id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-351222-9bfchw4u	Rollinger, Judith M.	Virtual screening for the discovery of bioactive natural products	2008		.txt	text/plain	10016	451	37	Some examples using high throughput docking as a structure-based virtual screening tool will be given here: Liu and Zhou applied a theoretical approach to find natural ligands as potential inhibitors of the SARS-CoV protease, a virus target of the severe acute respiratory syndrome [35] . Barreca and co-authors developed a 3D structure-based pharmacophore model with LIGANDSCOUT for the discovery of new scaffolds acting as HIV-1 non-nucleoside reverse transcriptase inhibitors by virtual screening of large chemical databases. Based on the co-crystal structure of AChE with its ligand galanthamine, a structure-based pharmacophore model was generated and used for an in silico screening of a multi-conformational database consisting of more than 110,000 NPs. From the obtained hit list, promising, virtually active candidates were selected, namely scopoletin (7) and its glucoside scopolin (8) .	./cache/cord-351222-9bfchw4u.txt	./txt/cord-351222-9bfchw4u.txt