id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-030679-27qrlapp	Yamamoto, Ryo	Oxygen administration in patients recovering from cardiac arrest: a narrative review	2020-08-12		.txt	text/plain	4288	239	37	In this review, we described the concept of brain injury following CA, the pathophysiology of hyperoxia, clinical studies of hyperoxia, the practical adjustment of oxygen administration, and ventilatory strategies for resuscitated patients. Although extensive research on improvement of clinical outcomes of patients recovering from CA has been conducted, the literature regarding post-cardiac arrest care practices to prevent neuronal cell dysfunction is limited [20] [21] [22] [23] . [8] conducted a systematic review and meta-analysis of eight retrospective studies, including those we mentioned above, and revealed that hyperoxia, defined as PaO 2 > 300 mmHg, correlated with increased in-hospital mortality (OR: 1.40 [1.02-1.93]), compared with normoxia. Several retrospective studies, a prospective observational study, and two systematic reviews demonstrated that exposure to PaO 2 > 300 mmHg during post-CA care is associated with unfavorable clinical outcomes, although the results are inconsistent. Study of Oxygen in Critical Care (SOCC) Group Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest	./cache/cord-030679-27qrlapp.txt	./txt/cord-030679-27qrlapp.txt