id author title date pages extension mime words sentences flesch summary cache txt cord-328056-y5x80tuw Popescu, Corneliu P. Hydroxychloroquine-azithromycin for COVID-19 – Warranted or dangerous? 2020-05-30 .txt text/plain 1123 68 52 (4) The seeming safety and effectiveness of hydroxychloroquine-azithromycin is in contradiction to data in a study published just a week earlier that showed dangerously increased death rates in hydroxychloroquine, chloroquine, and macrolide-treated patients.(5) That multi-nation registry of 96,032 hospitalized SARS-CoV-2 patients in 671 centers on six continents included 14,888 who were treated with chloroquine or hydroxychloroquine, with or without a macrolide.(5) Confounding factors were considered, and patients receiving remdesivir were excluded from the study. Widespread use of incompletely tested medications could potentially have dangerous side effects, and Million's group wisely did not include patients with identified risk for arrhythmia in their study. While some readers will be encouraged enough by the results of Million's study to "just do something" in giving hydroxychloroquine-azithromycin combined treatment to COVID-19 patients, others will opt to await more "proof" of safety and efficacy from randomized blinded controlled clinical trials. ./cache/cord-328056-y5x80tuw.txt ./txt/cord-328056-y5x80tuw.txt