id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-030026-4jew57ce	Vasala, Antti	Modern Tools for Rapid Diagnostics of Antimicrobial Resistance	2020-07-15		.txt	text/plain	14184	769	36	The CE-marked Alfed 60 AST TM system (Alifax, Italy) uses sensitive laser-light scattering technology to detect bacterial growth in a liquid culture broth and provides antimicrobial susceptibility results directly from positive blood culture bottles within 4-6 h. With 232 positive blood cultures tested, the overall essential agreement with routine methods was 95.1%, and the time needed for AST was decreased by 42 h in comparison to standard growth-based analysis. Regarding the speed and the need to handle clinical polybacterial samples, the immunodiagnostic TPX-technology (ArcDia Ltd), growth-based FISH (Accelerate Pheno), the Multipath digital imaging technology based on nanoparticles for labeling and magnetic beads for capturing (First Light Diagnostics Inc.) , and the NAAT-based dAST (Talis Inc.) seem promising options for rapid point-of-care testing of antimicrobial susceptibility. A novel microfluidic assay for rapid phenotypic antibiotic susceptibility testing of bacteria detected in clinical blood cultures	./cache/cord-030026-4jew57ce.txt	./txt/cord-030026-4jew57ce.txt