id author title date pages extension mime words sentences flesch summary cache txt cord-294877-bbs8a8jz Liu, ChuanPeng A glimpse of enzymology within the idea of systems 2012-09-27 .txt text/plain 5619 292 35 Fortunately, applications of new techniques and, in particular, wide acceptance of the idea of systems have enabled enzymologists to begin studying enzymes in the context of dynamic, complicated biological systems in recent years. Although these enzymes had been extensively studied, the results presented in three recently published articles indicate that their biological functions are still to be clarified. [23] investigated the po-tential effect of all the known nonsynonymous single nucleotide polymorphisms (nsSNPs) of human phase II metabolizing enzyme on protein function, and identified many residues that are likely to be functionally critical, but have not yet been studied experimentally. While molecular level research on biological systems has evolved from investigating individual enzymes or pathways to studies on biological networks and even ecological networks, a new challenge for biologists is to add a dynamic property to the constructed networks. ./cache/cord-294877-bbs8a8jz.txt ./txt/cord-294877-bbs8a8jz.txt