id author title date pages extension mime words sentences flesch summary cache txt cord-304869-l6a68tqn Bielińska-Wąż, Dorota Graphical and numerical representations of DNA sequences: statistical aspects of similarity 2011-08-28 .txt text/plain 15408 940 60 As a consequence, different aspects of similarity, as for example asymmetry of the gene structure, may be studied either using new similarity measures associated with four-component spectral representation of the DNA sequences or using alignment methods with corrections introduced in this paper. The corrections to the alignment methods and the statistical distribution moment-based descriptors derived from the four-component spectral representation of the DNA sequences are applied to similarity/dissimilarity studies of β-globin gene across species. How to restrict the graphs representing the sequences to two-dimensional plots and how to avoid degeneracies has been the subject of numerous studies which resulted in many graphical representations (see subsequent chapters). It is shown in the last chapter of this work that by using the four-component spectral representation one can recognize the difference in one base between a pair of sequences so it can be used for single nucleotide polymorfism (SNP) analyses which is subject of many investigation, as for example, in a recent work by Bhasi et al. ./cache/cord-304869-l6a68tqn.txt ./txt/cord-304869-l6a68tqn.txt