id author title date pages extension mime words sentences flesch summary cache txt cord-001169-6sfleb1b Chan, Ta-Chien Spatio-temporal analysis on enterovirus cases through integrated surveillance in Taiwan 2014-01-08 .txt text/plain 3807 193 54 CONCLUSIONS: Local public health professionals can monitor the temporal and spatial trends plus spatio-temporal clusters and isolation rate of EV-71 in mild and severe EV cases in a community when virus transmission is high, to provide early warning signals and to prevent subsequent severe epidemics. The specific aims of this study were: (1) to elucidate the spatio-temporal correlations between the mild and severe enterovirus cases through integrating the data of the three enterovirusrelated surveillance systems, including the sentinel physician, national notifiable diseases and laboratory surveillance systems in Taiwan, (2) to find out the feasibility of establishing an early warning signal using the increasing numbers of mild EV-71 cases and their lag time periods to appearance of severe EV-71 cases, and (3) to evaluate the trends of severe EV-71 cases over a 9.5-year period for providing better recommendations on public health efforts in the future. ./cache/cord-001169-6sfleb1b.txt ./txt/cord-001169-6sfleb1b.txt