id author title date pages extension mime words sentences flesch summary cache txt cord-300469-u6zjdqx6 Xu, Xiaojie New concepts and approaches for drug discovery based on traditional Chinese medicine 2006-11-09 .txt text/plain 3774 201 45 In this review, we report a new reverse approach (from finding bioactive molecules to separating target compounds in the related plant) by using virtual screening, immobilized enzyme and polyclonal antibody, molecularly imprinted polymers for finding, and separating the active compounds from TCM. In this review, we report a reverse approach (from finding bioactive molecules to separating target compounds in the related plant) by using virtual screening, immobilized enzymes, polyclonal antibodies and molecularly imprinted polymers (MIP) to find and separate the active compounds from TCM quickly and efficiently. So it is necessary for us to carry out drug discovery research by using available information and knowledge and developing new approaches for screening and separating the active compounds directly from TCM. MIP can be used to mimic the enzyme or receptor for direct screening, separation and online identification of active compounds from TCM, and can speed up drug discovery based on TCM. ./cache/cord-300469-u6zjdqx6.txt ./txt/cord-300469-u6zjdqx6.txt