id author title date pages extension mime words sentences flesch summary cache txt cord-336330-5m0fhoki Wong, R.W.K. Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study 2010-04-24 .txt text/plain 3065 170 49 Fructus armeniaca mume had inhibitory effects against Streptococcus mitis, Streptococcus sanguis, Streptococcus mutans and Porphyromonas gingivalis in vitro. Oral bacteria provide a good starting point for investigating the antimicrobial activities of TCM because the oral cavity is a strategic place for the development of infective disease and in vivo and clinical studies are easy to carry out. In this study, the authors investigate the antimicrobial activity of some TCMs that have been used to treat symptoms related to infection (e.g. fever, inflammation, cough) on several bacteria found in the oral biofilm to identify potential agents to control oral infections and diseases. The TCMs, Rhizoma coptidis and Galla chinensis, which showed potent antimicrobial activity against the four tested bacteria in the agar diffusion assay screening test, were selected for minimum inhibitory concentration (MIC) determination using the standard broth microdilution assay 2,6,7 . The authors compared the antimicrobial activity of TCMs with one effective oral antiseptic, chlorhexidine. ./cache/cord-336330-5m0fhoki.txt ./txt/cord-336330-5m0fhoki.txt