id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-016178-2ix6c0he	Rajan, V.	An Oral Vaccine for TGEV Immunization of Pigs	2014-05-28		.txt	text/plain	6053	291	47	These efforts towards the expression of the S-antigen of TGEV in maize seed, its effectiveness at inducing neutralizing antibody production in the colostrum of gilts, and its efficacy in protecting piglets against challenge by virulent TGEV are summarized here. Potentially, the methods to protect naïve piglets at highest risk from TGEV infection are to provide immune colostrum by vaccinating sows and an oral/nasal vaccine to boost secretory neutralizing antibody levels. The induction of neutralizing antibodies in both serum and colostrum was examined in gilts following the administration of oral TGEV vaccine in maize comprising a subunit vaccine of the S-protein expressed in corn (Lamphear et al. Administration of antigen over a 4-day period gave the highest levels of protection against live challengeeven higher than oral vaccination with a modified live virus (Fig. 8.4 ; see Sect. Protection with a subunit antigen expressed in corn, exclusively by the oral route, is shown for the first time to be effective in piglets, the target species for immunization.	./cache/cord-016178-2ix6c0he.txt	./txt/cord-016178-2ix6c0he.txt