id author title date pages extension mime words sentences flesch summary cache txt cord-289389-xailjga5 Wang, Xiaoli Comparing early outbreak detection algorithms based on their optimized parameter values 2009-08-13 .txt text/plain 5152 297 56 BACKGROUND: Many researchers have evaluated the performance of outbreak detection algorithms with recommended parameter values. METHODS: Based on reported case counts of bacillary dysentery from 2005 to 2007 in Beijing, semi-synthetic datasets containing outbreak signals were simulated to evaluate the performance of five outbreak detection algorithms. We compared the performance of five outbreak detection algorithms, the exponential weighted moving average (EWMA), C1-MILD (C1), C2-MEDIUM (C2), C3-ULTRA (C3) and the spacetime permutation scan statistic model. The correlation coefficients between the three evaluation indices (sensitivity, specificity and time to detection) and parameter values were calculated. All algorithms showed strong relation between the evaluation indices and the parameter' values, except space-time permutation scan statistic. In our study we found that space-time permutation scan statistics and the EWMA outperformed other algorithms both in terms of timeliness and accuracy for detecting bacillary dysentery outbreaks. ./cache/cord-289389-xailjga5.txt ./txt/cord-289389-xailjga5.txt