id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349548-loi1vs5y	Mueller, Markus	Using random testing in a feedback-control loop to manage a safe exit from the COVID-19 lockdown	2020-04-14		.txt	text/plain	11227	815	68	We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by restrictive measures, and anticipates the load on the healthcare system due to progression of the disease. Here we suggest, irrespective of the size of a suitably homogeneous population, a conservative estimate of 15000 for the number of randomly tested people per day which will suffice to obtain reliable data about the current fraction of infections and its evolution in time, thus enabling close to real-time assessment of the quantitative effect of restrictive measures. In the absence of a substantial influx of infected people from outside the country, and provided infection numbers are below a critical value, the optimal target of the growth rate is k = 0, corresponding to a marginally stable state, where infections neither grow nor decrease exponentially with time.	./cache/cord-349548-loi1vs5y.txt	./txt/cord-349548-loi1vs5y.txt