id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-005664-n4xv247l	Plötz, Frans B.	Mechanical ventilation alters the immune response in children without lung pathology	2002-01-15		.txt	text/plain	3292	182	41	In the tracheal aspirates the immune balance was characterized by a proinflammatory response pattern, with a significant increase in TNF-α and IL-6 concentrations; concentrations of anti-inflammatory mediators remained very low. Conclusions: Two hours of servoflurane and mechanical ventilation using a tidal volume of 10 ml/kg is associated with remarkable changes in the immune response in infants without preexisting lung pathology undergoing cardiac catheterization. Conclusions: Two hours of servoflurane and mechanical ventilation using a tidal volume of 10 ml/kg is associated with remarkable changes in the immune response in infants without preexisting lung pathology undergoing cardiac catheterization. The major finding of the present study is that exposing infants with normal lung function to 2 h of volatile anesthetics, mechanical ventilation, and cardiac catheterization is associated with remarkable changes in immune responses. We observed a proinflammatory response in the lungs with a significant increase in TNF-α, while antiinflammatory cytokine concentrations in tracheal aspirates remained virtually unchanged, just above the detection level.	./cache/cord-005664-n4xv247l.txt	./txt/cord-005664-n4xv247l.txt