id author title date pages extension mime words sentences flesch summary cache txt cord-017309-pt27efu1 Gupta, G. S. Selectins and Associated Adhesion Proteins in Inflammatory disorders 2012-03-20 .txt text/plain 25423 1303 40 Activation of endothelial cells (EC) with different stimuli induces the expression of E-and P-selectins, and other adhesion molecules (ICAM-1, VCAM-1), involved in their interaction with circulating cells. Accordingly, population studies have explored the association of ischaemic heart disease with gene polymorphisms of the inflammatory molecules: tumor necrosis factors (TNF) a and b, transforming growth factors (TGF) b1 and 2, P and E selectins, and platelet endothelial cell adhesion molecule (PECAM) 1. Endothelial dysfunction in type 2 diabetic patients is associated with inflammation, increased levels of circulating soluble adhesion molecules (VCAM-1 and E-selectin), and inducing production of ROS, and urinary albumin excretion (Potenza et al. The A 561 C polymorphism of E-selectin gene may be associated with disease progression in patients with chronic HBV infection and control the expression of plasma soluble levels, while the G 98 T polymorphism may be related to fibrotic severity in Chinese population (Wu et al. ./cache/cord-017309-pt27efu1.txt ./txt/cord-017309-pt27efu1.txt