id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-021266-afs9eb40	El Gendy, Fady M.	The role of Tumor necrosis factor alpha −308 G>A promoter polymorphism in pediatric community acquired pneumonia	2020-02-10		.txt	text/plain	3756	222	50	Our objective was to evaluate the association of TNF-α gene −308 G>A polymorphism with susceptibility to, and severity of, community-acquired pneumonia (CAP). We found no significant association of alleles or genotypes with any indicators of CAP severity, including clinical severity scores, but we were not able to assess the influence of TNF-α polymorphism on mortality since none of our patients died. Consistent with our findings, genotyping of 77 children with respiratory syncytial virus infection revealed no association of TNF-α −308 G>A polymorphism with any of the clinical outcomes, including severity scores of lower respiratory illness, oxygen saturation, lengths of oxygen supplementation, intensive care unit (ICU) and hospital stays, and the presence or absence of pneumonia and otitis media [25] . However, another study of 277 Chinese adult patients with severe pneumonia-induced sepsis found that TNF-α "A" allele increased the risk of septic shock (OR = 4.28).	./cache/cord-021266-afs9eb40.txt	./txt/cord-021266-afs9eb40.txt