id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023935-o2ffxgnn	Lorts, Angela	Sepsis	2011-12-16		.txt	text/plain	11110	510	38	SIRS i s a state of infl ammatory/ immune activation and is based on the presence of at least two of the four following clinical criteria: Temperature >38°C or <36°C, heart rate >90th percentile for age, respiratory rate >90th percentile for age, or hyperventilation to PaCO 2 < 32 mm Hg. The defi nition attempts to "capture" all patients at risk for the subsequent development of severe sepsis or septic shock. Among these, the nuclear factor-k B (NF-k b ) and the mitogen activated protein kinase (MAPK) pathways play a prominent role in regulating the expression of a number of infl ammatory gene products key to propagating the sepsis response. Nuclear factork B (NFk b ) and the mitogen activated protein kinase (MAPK) pathways play a prominent role in regulating the expression of a number of infl ammatory gene products key to propagating the sepsis response.	./cache/cord-023935-o2ffxgnn.txt	./txt/cord-023935-o2ffxgnn.txt