id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-267270-r17z4d8x	Kipar, A.	Age-related dynamics of constitutive cytokine transcription levels of feline monocytes	2005-01-18		.txt	text/plain	2695	141	53	However, in order to characterize the effect of age, feline monocyte functions were examined for changes in cytokine transcription levels in early stages of immunosenescence. For this purpose, isolated, short-term cultured monocytes from barrier-maintained adult cats of different ages (15 mo to 10 yr) were examined for transcription of IL-1β, IL-6, IL-10, IL-12 p40 and TNF-α by real-time PCR. One previous study actually showed significantly increased constitutive production of IL-1b and IL-6 in circulating monocytes of older female compared to young adult female human individuals, whereas no changes in the constitutive TNF-a production were observed (Sadeghi et al., 1999) . It seems plausible that despite increased or similar constitutive cytokine transcription, monocytes of older cats might exhibit an impaired reactive activation after virus infection (Kipar et al., 2005) .	./cache/cord-267270-r17z4d8x.txt	./txt/cord-267270-r17z4d8x.txt