id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322250-7kjakuyw	He, Jia	Anemoside B4 protects against Klebsiella pneumoniae- and influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice	2020-07-02		.txt	text/plain	4895	285	46	title: Anemoside B4 protects against Klebsiella pneumoniaeand influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice This study aims to investigate that anemoside B4 attenuates the inflammatory responses in Klebsiella pneumonia (KP)and influenza virus FM1 (FM1)-induced pneumonia mice model. The counts of neutrophil (NEU) and white blood cell (WBC), the level of myeloperoxidase (MPO), and the release of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 increased by KP or FM1 infection, which were reversed by anemoside B4. In addition, significant increase was observed in the TNF-α (Fig. 3d, g) , IL-6 ( Fig. 3e, h) , IL-1β (Fig. 3f ) , and MPO (Fig. 3i) in the BALF and lung tissue samples collected from the KP-infected pneumonia mice, which were reversed by anemoside B4. Influenza virus FM1-infected pneumonia leads to an inflammatory storm, suggesting that many pro-inflammatory cytokines like TNF-α and IL-6 released into blood and lung tissue [28] [29] [30] .	./cache/cord-322250-7kjakuyw.txt	./txt/cord-322250-7kjakuyw.txt