id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341667-ayl71jpc	Van Reeth, Kristien	Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans?	1998-04-17		.txt	text/plain	1959	121	48	Biologically active interferon-a, tumor necrosis factor-a (TNF-a), and interleukin-1 (IL-1) were detected in bronchoalveolar lavage (BAL) fluids of 3-week-old cesarian-derived colostrum-deprived pigs inoculated with H1N1 influenza virus. Biologically active interferon-a, tumor necrosis factor-a (TNF-a), and interleukin-1 (IL-1) were detected in bronchoalveolar lavage (BAL) fluids of 3-week-old cesarian-derived colostrum-deprived pigs inoculated with H1N1 influenza virus. Levels of the three cytokines were significantly higher 18 -24 h after inoculation than at 48 -72 h after inoculation (P õ Clinical responses, influenza virus titers, BAL cell numbers, percentage of neutrophils, and cytokine titers of individual pigs .016 for all three cytokines). On histopathology, bronchi/bronchioli and, to a lesser degree, alveoli showed epithelial necrosis and To our knowledge, this is the first demonstration of influenza virus -induced TNF-a and IL-1 in BAL fluids of a natural virus massive neutrophil infiltration at 18 -24 h after inoculation.	./cache/cord-341667-ayl71jpc.txt	./txt/cord-341667-ayl71jpc.txt