id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347298-7kqrl3rv	Hedger, M.P.	Immunology of the Testis and Male Reproductive Tract	2010-07-12		.txt	text/plain	21168	1000	46	Thus, it appears unlikely that a lack of APCs is a contributing factor in testicular immune privilege, although differences in the number and distribution of MHC class II-expressing cells in the interstitial tissue of different species or strains may help to explain differences in susceptibility to autoimmune orchitis (Flickinger et al. Moreover, while inhibition of Leydig cell steroidogenesis during inflammation may involve indirect effects at the level of the pituitary, or the actions of inflammatory mediators produced by the testicular macrophages and Sertoli cells, there is evidence that these cells can also respond directly to TLR ligands (Bhushan et al. Activation of p38/Jnk is implicated in the stimulation of proliferation by immature Sertoli cells and the regulation of blood-testis barrier dynamics, steroidogenesis, and multiple inflammatory responses, including the production of IL6, iNOS, monocyte chemoattractant protein 1, and leukocyte adhesion molecules, in the mature Sertoli cell (De Cesaris et al.	./cache/cord-347298-7kqrl3rv.txt	./txt/cord-347298-7kqrl3rv.txt