id sid tid token lemma pos cord-022526-j9kg00qf 1 1 key key JJ cord-022526-j9kg00qf 1 2 : : : cord-022526-j9kg00qf 1 3 cord-022526-j9kg00qf cord-022526-j9kg00qf JJ cord-022526-j9kg00qf 1 4 authors author NNS cord-022526-j9kg00qf 1 5 : : : cord-022526-j9kg00qf 1 6 Jones Jones NNP cord-022526-j9kg00qf 1 7 , , , cord-022526-j9kg00qf 1 8 Samuel Samuel NNP cord-022526-j9kg00qf 1 9 L. L. NNP cord-022526-j9kg00qf 1 10 ; ; : cord-022526-j9kg00qf 1 11 Blikslager Blikslager NNP cord-022526-j9kg00qf 1 12 , , , cord-022526-j9kg00qf 1 13 Anthony Anthony NNP cord-022526-j9kg00qf 1 14 T. T. NNP cord-022526-j9kg00qf 2 1 title title NN cord-022526-j9kg00qf 2 2 : : : cord-022526-j9kg00qf 2 3 Disorders disorder NNS cord-022526-j9kg00qf 2 4 of of IN cord-022526-j9kg00qf 2 5 the the DT cord-022526-j9kg00qf 2 6 Gastrointestinal Gastrointestinal NNP cord-022526-j9kg00qf 2 7 System System NNP cord-022526-j9kg00qf 2 8 date date NN cord-022526-j9kg00qf 2 9 : : : cord-022526-j9kg00qf 2 10 2009 2009 CD cord-022526-j9kg00qf 2 11 - - SYM cord-022526-j9kg00qf 2 12 05 05 CD cord-022526-j9kg00qf 2 13 - - SYM cord-022526-j9kg00qf 2 14 18 18 CD cord-022526-j9kg00qf 2 15 journal journal NN cord-022526-j9kg00qf 2 16 : : : cord-022526-j9kg00qf 3 1 Equine Equine NNP cord-022526-j9kg00qf 3 2 Internal Internal NNP cord-022526-j9kg00qf 3 3 Medicine Medicine NNP cord-022526-j9kg00qf 3 4 DOI DOI NNP cord-022526-j9kg00qf 3 5 : : : cord-022526-j9kg00qf 3 6 10.1016 10.1016 CD cord-022526-j9kg00qf 3 7 / / SYM cord-022526-j9kg00qf 3 8 b0 b0 NN cord-022526-j9kg00qf 3 9 - - HYPH cord-022526-j9kg00qf 3 10 72 72 CD cord-022526-j9kg00qf 3 11 - - HYPH cord-022526-j9kg00qf 3 12 169777 169777 CD cord-022526-j9kg00qf 3 13 - - HYPH cord-022526-j9kg00qf 3 14 1/50015 1/50015 CD cord-022526-j9kg00qf 3 15 - - SYM cord-022526-j9kg00qf 3 16 9 9 CD cord-022526-j9kg00qf 3 17 sha sha NN cord-022526-j9kg00qf 3 18 : : : cord-022526-j9kg00qf 3 19 9d118e16908ed81fea07403ca6deef78623dd14d 9d118e16908ed81fea07403ca6deef78623dd14d CD cord-022526-j9kg00qf 3 20 doc_id doc_id CD cord-022526-j9kg00qf 3 21 : : : cord-022526-j9kg00qf 3 22 22526 22526 CD cord-022526-j9kg00qf 3 23 cord_uid cord_uid NNS cord-022526-j9kg00qf 3 24 : : : cord-022526-j9kg00qf 4 1 j9kg00qf j9kg00qf NNP cord-022526-j9kg00qf 4 2 nan nan NNP cord-022526-j9kg00qf 4 3 however however RB cord-022526-j9kg00qf 4 4 , , , cord-022526-j9kg00qf 4 5 the the DT cord-022526-j9kg00qf 4 6 abdominal abdominal JJ cord-022526-j9kg00qf 4 7 wall wall NN cord-022526-j9kg00qf 4 8 is be VBZ cord-022526-j9kg00qf 4 9 too too RB cord-022526-j9kg00qf 4 10 rigid rigid JJ cord-022526-j9kg00qf 4 11 to to TO cord-022526-j9kg00qf 4 12 allow allow VB cord-022526-j9kg00qf 4 13 effective effective JJ cord-022526-j9kg00qf 4 14 palpation palpation NN cord-022526-j9kg00qf 4 15 of of IN cord-022526-j9kg00qf 4 16 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 4 17 structures structure NNS cord-022526-j9kg00qf 4 18 . . . cord-022526-j9kg00qf 5 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5 2 auscultation auscultation NN cord-022526-j9kg00qf 5 3 is be VBZ cord-022526-j9kg00qf 5 4 particularly particularly RB cord-022526-j9kg00qf 5 5 useful useful JJ cord-022526-j9kg00qf 5 6 for for IN cord-022526-j9kg00qf 5 7 assessing assess VBG cord-022526-j9kg00qf 5 8 the the DT cord-022526-j9kg00qf 5 9 motility motility NN cord-022526-j9kg00qf 5 10 of of IN cord-022526-j9kg00qf 5 11 the the DT cord-022526-j9kg00qf 5 12 large large JJ cord-022526-j9kg00qf 5 13 intestine intestine NN cord-022526-j9kg00qf 5 14 . . . cord-022526-j9kg00qf 6 1 Progressive progressive JJ cord-022526-j9kg00qf 6 2 motility motility NN cord-022526-j9kg00qf 6 3 of of IN cord-022526-j9kg00qf 6 4 the the DT cord-022526-j9kg00qf 6 5 small small JJ cord-022526-j9kg00qf 6 6 intestine intestine NN cord-022526-j9kg00qf 6 7 , , , cord-022526-j9kg00qf 6 8 conversely conversely RB cord-022526-j9kg00qf 6 9 , , , cord-022526-j9kg00qf 6 10 is be VBZ cord-022526-j9kg00qf 6 11 difficult difficult JJ cord-022526-j9kg00qf 6 12 to to TO cord-022526-j9kg00qf 6 13 distinguish distinguish VB cord-022526-j9kg00qf 6 14 by by IN cord-022526-j9kg00qf 6 15 auscultation auscultation NN cord-022526-j9kg00qf 6 16 from from IN cord-022526-j9kg00qf 6 17 nonprogressive nonprogressive JJ cord-022526-j9kg00qf 6 18 motility motility NN cord-022526-j9kg00qf 6 19 . . . cord-022526-j9kg00qf 7 1 The the DT cord-022526-j9kg00qf 7 2 distinct distinct JJ cord-022526-j9kg00qf 7 3 character character NN cord-022526-j9kg00qf 7 4 of of IN cord-022526-j9kg00qf 7 5 the the DT cord-022526-j9kg00qf 7 6 borborygmi borborygmi NN cord-022526-j9kg00qf 7 7 produced produce VBN cord-022526-j9kg00qf 7 8 during during IN cord-022526-j9kg00qf 7 9 propulsive propulsive JJ cord-022526-j9kg00qf 7 10 contractions contraction NNS cord-022526-j9kg00qf 7 11 of of IN cord-022526-j9kg00qf 7 12 the the DT cord-022526-j9kg00qf 7 13 cecum cecum NN cord-022526-j9kg00qf 7 14 and and CC cord-022526-j9kg00qf 7 15 ascending ascend VBG cord-022526-j9kg00qf 7 16 colon colon NN cord-022526-j9kg00qf 7 17 allow allow VBP cord-022526-j9kg00qf 7 18 evaluation evaluation NN cord-022526-j9kg00qf 7 19 of of IN cord-022526-j9kg00qf 7 20 the the DT cord-022526-j9kg00qf 7 21 frequency frequency NN cord-022526-j9kg00qf 7 22 and and CC cord-022526-j9kg00qf 7 23 strength strength NN cord-022526-j9kg00qf 7 24 of of IN cord-022526-j9kg00qf 7 25 retropulsion retropulsion NN cord-022526-j9kg00qf 7 26 and and CC cord-022526-j9kg00qf 7 27 propulsion propulsion NN cord-022526-j9kg00qf 7 28 . . . cord-022526-j9kg00qf 8 1 Propulsive propulsive JJ cord-022526-j9kg00qf 8 2 contractions contraction NNS cord-022526-j9kg00qf 8 3 of of IN cord-022526-j9kg00qf 8 4 the the DT cord-022526-j9kg00qf 8 5 cecum cecum NN cord-022526-j9kg00qf 8 6 and and CC cord-022526-j9kg00qf 8 7 ventral ventral JJ cord-022526-j9kg00qf 8 8 colon colon NN cord-022526-j9kg00qf 8 9 occur occur VBP cord-022526-j9kg00qf 8 10 every every DT cord-022526-j9kg00qf 8 11 3 3 CD cord-022526-j9kg00qf 8 12 to to TO cord-022526-j9kg00qf 8 13 4 4 CD cord-022526-j9kg00qf 8 14 minutes minute NNS cord-022526-j9kg00qf 8 15 and and CC cord-022526-j9kg00qf 8 16 give give VB cord-022526-j9kg00qf 8 17 rise rise NN cord-022526-j9kg00qf 8 18 to to IN cord-022526-j9kg00qf 8 19 prolonged prolonged JJ cord-022526-j9kg00qf 8 20 rushing rushing NN cord-022526-j9kg00qf 8 21 sounds sound NNS cord-022526-j9kg00qf 8 22 heard hear VBN cord-022526-j9kg00qf 8 23 over over IN cord-022526-j9kg00qf 8 24 long long JJ cord-022526-j9kg00qf 8 25 segments segment NNS cord-022526-j9kg00qf 8 26 of of IN cord-022526-j9kg00qf 8 27 intestine intestine NN cord-022526-j9kg00qf 8 28 . . . cord-022526-j9kg00qf 9 1 Retropulsive Retropulsive NNP cord-022526-j9kg00qf 9 2 sounds sound NNS cord-022526-j9kg00qf 9 3 presumably presumably RB cord-022526-j9kg00qf 9 4 are be VBP cord-022526-j9kg00qf 9 5 similar similar JJ cord-022526-j9kg00qf 9 6 to to IN cord-022526-j9kg00qf 9 7 propulsive propulsive JJ cord-022526-j9kg00qf 9 8 sounds sound NNS cord-022526-j9kg00qf 9 9 , , , cord-022526-j9kg00qf 9 10 but but CC cord-022526-j9kg00qf 9 11 they -PRON- PRP cord-022526-j9kg00qf 9 12 occur occur VBP cord-022526-j9kg00qf 9 13 less less RBR cord-022526-j9kg00qf 9 14 frequently frequently RB cord-022526-j9kg00qf 9 15 . . . cord-022526-j9kg00qf 10 1 The the DT cord-022526-j9kg00qf 10 2 distinction distinction NN cord-022526-j9kg00qf 10 3 of of IN cord-022526-j9kg00qf 10 4 propulsion propulsion NN cord-022526-j9kg00qf 10 5 from from IN cord-022526-j9kg00qf 10 6 retropulsion retropulsion NN cord-022526-j9kg00qf 10 7 is be VBZ cord-022526-j9kg00qf 10 8 not not RB cord-022526-j9kg00qf 10 9 important important JJ cord-022526-j9kg00qf 10 10 clinically clinically RB cord-022526-j9kg00qf 10 11 because because IN cord-022526-j9kg00qf 10 12 both both DT cord-022526-j9kg00qf 10 13 types type NNS cord-022526-j9kg00qf 10 14 of of IN cord-022526-j9kg00qf 10 15 contractions contraction NNS cord-022526-j9kg00qf 10 16 signify signify VBP cord-022526-j9kg00qf 10 17 normal normal JJ cord-022526-j9kg00qf 10 18 motility motility NN cord-022526-j9kg00qf 10 19 . . . cord-022526-j9kg00qf 11 1 Inter Inter NNP cord-022526-j9kg00qf 11 2 - - : cord-022526-j9kg00qf 11 3 and and CC cord-022526-j9kg00qf 11 4 intrahaustral intrahaustral JJ cord-022526-j9kg00qf 11 5 mixing mix VBG cord-022526-j9kg00qf 11 6 contractions contraction NNS cord-022526-j9kg00qf 11 7 produce produce VBP cord-022526-j9kg00qf 11 8 nonspecific nonspecific JJ cord-022526-j9kg00qf 11 9 sounds sound NNS cord-022526-j9kg00qf 11 10 of of IN cord-022526-j9kg00qf 11 11 fluid fluid JJ cord-022526-j9kg00qf 11 12 and and CC cord-022526-j9kg00qf 11 13 ingesta ingesta JJ cord-022526-j9kg00qf 11 14 movement movement NN cord-022526-j9kg00qf 11 15 that that WDT cord-022526-j9kg00qf 11 16 are be VBP cord-022526-j9kg00qf 11 17 difficult difficult JJ cord-022526-j9kg00qf 11 18 to to TO cord-022526-j9kg00qf 11 19 distinguish distinguish VB cord-022526-j9kg00qf 11 20 from from IN cord-022526-j9kg00qf 11 21 other other JJ cord-022526-j9kg00qf 11 22 borborygmi borborygmi NN cord-022526-j9kg00qf 11 23 , , , cord-022526-j9kg00qf 11 24 such such JJ cord-022526-j9kg00qf 11 25 as as IN cord-022526-j9kg00qf 11 26 small small JJ cord-022526-j9kg00qf 11 27 intestinal intestinal JJ cord-022526-j9kg00qf 11 28 contractions contraction NNS cord-022526-j9kg00qf 11 29 or or CC cord-022526-j9kg00qf 11 30 spasmodic spasmodic JJ cord-022526-j9kg00qf 11 31 contractions contraction NNS cord-022526-j9kg00qf 11 32 . . . cord-022526-j9kg00qf 12 1 1 1 CD cord-022526-j9kg00qf 12 2 Auscultation auscultation NN cord-022526-j9kg00qf 12 3 over over IN cord-022526-j9kg00qf 12 4 the the DT cord-022526-j9kg00qf 12 5 right right JJ cord-022526-j9kg00qf 12 6 flank flank NN cord-022526-j9kg00qf 12 7 and and CC cord-022526-j9kg00qf 12 8 proceeding proceeding NN cord-022526-j9kg00qf 12 9 along along IN cord-022526-j9kg00qf 12 10 the the DT cord-022526-j9kg00qf 12 11 caudal caudal JJ cord-022526-j9kg00qf 12 12 edge edge NN cord-022526-j9kg00qf 12 13 of of IN cord-022526-j9kg00qf 12 14 the the DT cord-022526-j9kg00qf 12 15 costal costal JJ cord-022526-j9kg00qf 12 16 margin margin NN cord-022526-j9kg00qf 12 17 toward toward IN cord-022526-j9kg00qf 12 18 the the DT cord-022526-j9kg00qf 12 19 xiphoid xiphoid NN cord-022526-j9kg00qf 12 20 allows allow VBZ cord-022526-j9kg00qf 12 21 evaluation evaluation NN cord-022526-j9kg00qf 12 22 of of IN cord-022526-j9kg00qf 12 23 the the DT cord-022526-j9kg00qf 12 24 cecal cecal JJ cord-022526-j9kg00qf 12 25 borborygmi borborygmi NN cord-022526-j9kg00qf 12 26 . . . cord-022526-j9kg00qf 13 1 Auscultation auscultation NN cord-022526-j9kg00qf 13 2 over over IN cord-022526-j9kg00qf 13 3 a a DT cord-022526-j9kg00qf 13 4 similar similar JJ cord-022526-j9kg00qf 13 5 area area NN cord-022526-j9kg00qf 13 6 on on IN cord-022526-j9kg00qf 13 7 the the DT cord-022526-j9kg00qf 13 8 left left JJ cord-022526-j9kg00qf 13 9 side side NN cord-022526-j9kg00qf 13 10 allows allow VBZ cord-022526-j9kg00qf 13 11 evaluation evaluation NN cord-022526-j9kg00qf 13 12 of of IN cord-022526-j9kg00qf 13 13 the the DT cord-022526-j9kg00qf 13 14 pelvic pelvic JJ cord-022526-j9kg00qf 13 15 flexure flexure NN cord-022526-j9kg00qf 13 16 and and CC cord-022526-j9kg00qf 13 17 ascending ascend VBG cord-022526-j9kg00qf 13 18 colon colon NN cord-022526-j9kg00qf 13 19 . . . cord-022526-j9kg00qf 14 1 Typical typical JJ cord-022526-j9kg00qf 14 2 progressive progressive JJ cord-022526-j9kg00qf 14 3 borborygmi borborygmi NN cord-022526-j9kg00qf 14 4 heard hear VBD cord-022526-j9kg00qf 14 5 every every DT cord-022526-j9kg00qf 14 6 3 3 CD cord-022526-j9kg00qf 14 7 to to TO cord-022526-j9kg00qf 14 8 4 4 CD cord-022526-j9kg00qf 14 9 minutes minute NNS cord-022526-j9kg00qf 14 10 on on IN cord-022526-j9kg00qf 14 11 both both DT cord-022526-j9kg00qf 14 12 sides side NNS cord-022526-j9kg00qf 14 13 of of IN cord-022526-j9kg00qf 14 14 the the DT cord-022526-j9kg00qf 14 15 abdomen abdoman NNS cord-022526-j9kg00qf 14 16 indicate indicate VBP cord-022526-j9kg00qf 14 17 normal normal JJ cord-022526-j9kg00qf 14 18 motility motility NN cord-022526-j9kg00qf 14 19 of of IN cord-022526-j9kg00qf 14 20 the the DT cord-022526-j9kg00qf 14 21 cecum cecum NN cord-022526-j9kg00qf 14 22 and and CC cord-022526-j9kg00qf 14 23 ascending ascend VBG cord-022526-j9kg00qf 14 24 colon colon NN cord-022526-j9kg00qf 14 25 . . . cord-022526-j9kg00qf 15 1 Less less RBR cord-022526-j9kg00qf 15 2 frequent frequent JJ cord-022526-j9kg00qf 15 3 progressive progressive JJ cord-022526-j9kg00qf 15 4 sounds sound NNS cord-022526-j9kg00qf 15 5 may may MD cord-022526-j9kg00qf 15 6 indicate indicate VB cord-022526-j9kg00qf 15 7 a a DT cord-022526-j9kg00qf 15 8 pathologic pathologic JJ cord-022526-j9kg00qf 15 9 condition condition NN cord-022526-j9kg00qf 15 10 of of IN cord-022526-j9kg00qf 15 11 the the DT cord-022526-j9kg00qf 15 12 large large JJ cord-022526-j9kg00qf 15 13 intestine intestine NN cord-022526-j9kg00qf 15 14 or or CC cord-022526-j9kg00qf 15 15 may may MD cord-022526-j9kg00qf 15 16 result result VB cord-022526-j9kg00qf 15 17 from from IN cord-022526-j9kg00qf 15 18 anorexia anorexia NN cord-022526-j9kg00qf 15 19 , , , cord-022526-j9kg00qf 15 20 nervousness nervousness NN cord-022526-j9kg00qf 15 21 ( ( -LRB- cord-022526-j9kg00qf 15 22 sympathetic sympathetic JJ cord-022526-j9kg00qf 15 23 tone tone NN cord-022526-j9kg00qf 15 24 ) ) -RRB- cord-022526-j9kg00qf 15 25 , , , cord-022526-j9kg00qf 15 26 or or CC cord-022526-j9kg00qf 15 27 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 15 28 inhibition inhibition NN cord-022526-j9kg00qf 15 29 of of IN cord-022526-j9kg00qf 15 30 _SP cord-022526-j9kg00qf 15 31 Examination Examination NNP cord-022526-j9kg00qf 15 32 of of IN cord-022526-j9kg00qf 15 33 patients patient NNS cord-022526-j9kg00qf 15 34 with with IN cord-022526-j9kg00qf 15 35 disease disease NN cord-022526-j9kg00qf 15 36 of of IN cord-022526-j9kg00qf 15 37 the the DT cord-022526-j9kg00qf 15 38 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 15 39 tract tract NN cord-022526-j9kg00qf 15 40 must must MD cord-022526-j9kg00qf 15 41 include include VB cord-022526-j9kg00qf 15 42 evaluation evaluation NN cord-022526-j9kg00qf 15 43 of of IN cord-022526-j9kg00qf 15 44 the the DT cord-022526-j9kg00qf 15 45 metabolic metabolic JJ cord-022526-j9kg00qf 15 46 and and CC cord-022526-j9kg00qf 15 47 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 15 48 status status NN cord-022526-j9kg00qf 15 49 of of IN cord-022526-j9kg00qf 15 50 the the DT cord-022526-j9kg00qf 15 51 patient patient NN cord-022526-j9kg00qf 15 52 , , , cord-022526-j9kg00qf 15 53 because because IN cord-022526-j9kg00qf 15 54 acute acute JJ cord-022526-j9kg00qf 15 55 conditions condition NNS cord-022526-j9kg00qf 15 56 of of IN cord-022526-j9kg00qf 15 57 the the DT cord-022526-j9kg00qf 15 58 proximal proximal JJ cord-022526-j9kg00qf 15 59 or or CC cord-022526-j9kg00qf 15 60 distal distal JJ cord-022526-j9kg00qf 15 61 intestinal intestinal JJ cord-022526-j9kg00qf 15 62 tract tract NN cord-022526-j9kg00qf 15 63 have have VBP cord-022526-j9kg00qf 15 64 the the DT cord-022526-j9kg00qf 15 65 potential potential NN cord-022526-j9kg00qf 15 66 to to TO cord-022526-j9kg00qf 15 67 lead lead VB cord-022526-j9kg00qf 15 68 to to IN cord-022526-j9kg00qf 15 69 endotoxemia endotoxemia NN cord-022526-j9kg00qf 15 70 and and CC cord-022526-j9kg00qf 15 71 sepsis sepsis NN cord-022526-j9kg00qf 15 72 . . . cord-022526-j9kg00qf 16 1 Examination examination NN cord-022526-j9kg00qf 16 2 of of IN cord-022526-j9kg00qf 16 3 the the DT cord-022526-j9kg00qf 16 4 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 16 5 system system NN cord-022526-j9kg00qf 16 6 ( ( -LRB- cord-022526-j9kg00qf 16 7 heart heart NN cord-022526-j9kg00qf 16 8 , , , cord-022526-j9kg00qf 16 9 peripheral peripheral JJ cord-022526-j9kg00qf 16 10 pulse pulse NN cord-022526-j9kg00qf 16 11 , , , cord-022526-j9kg00qf 16 12 and and CC cord-022526-j9kg00qf 16 13 mucous mucous JJ cord-022526-j9kg00qf 16 14 membranes membrane NNS cord-022526-j9kg00qf 16 15 ) ) -RRB- cord-022526-j9kg00qf 16 16 , , , cord-022526-j9kg00qf 16 17 lungs lung NNS cord-022526-j9kg00qf 16 18 , , , cord-022526-j9kg00qf 16 19 and and CC cord-022526-j9kg00qf 16 20 abdomen abdomen NN cord-022526-j9kg00qf 16 21 is be VBZ cord-022526-j9kg00qf 16 22 essential essential JJ cord-022526-j9kg00qf 16 23 to to TO cord-022526-j9kg00qf 16 24 detect detect VB cord-022526-j9kg00qf 16 25 clinical clinical JJ cord-022526-j9kg00qf 16 26 signs sign NNS cord-022526-j9kg00qf 16 27 of of IN cord-022526-j9kg00qf 16 28 systemic systemic JJ cord-022526-j9kg00qf 16 29 inflammation inflammation NN cord-022526-j9kg00qf 16 30 from from IN cord-022526-j9kg00qf 16 31 endotoxemia endotoxemia NN cord-022526-j9kg00qf 16 32 , , , cord-022526-j9kg00qf 16 33 coagulation coagulation NN cord-022526-j9kg00qf 16 34 disorders disorder NNS cord-022526-j9kg00qf 16 35 , , , cord-022526-j9kg00qf 16 36 dehydration dehydration NN cord-022526-j9kg00qf 16 37 , , , cord-022526-j9kg00qf 16 38 ileus ileus NN cord-022526-j9kg00qf 16 39 , , , cord-022526-j9kg00qf 16 40 shock shock NN cord-022526-j9kg00qf 16 41 , , , cord-022526-j9kg00qf 16 42 and and CC cord-022526-j9kg00qf 16 43 other other JJ cord-022526-j9kg00qf 16 44 abnormalities abnormality NNS cord-022526-j9kg00qf 16 45 resulting result VBG cord-022526-j9kg00qf 16 46 from from IN cord-022526-j9kg00qf 16 47 injury injury NN cord-022526-j9kg00qf 16 48 to to IN cord-022526-j9kg00qf 16 49 the the DT cord-022526-j9kg00qf 16 50 small small JJ cord-022526-j9kg00qf 16 51 or or CC cord-022526-j9kg00qf 16 52 large large JJ cord-022526-j9kg00qf 16 53 intestine intestine NN cord-022526-j9kg00qf 16 54 . . . cord-022526-j9kg00qf 17 1 Chapter chapter NN cord-022526-j9kg00qf 17 2 13.7 13.7 CD cord-022526-j9kg00qf 17 3 covers cover VBZ cord-022526-j9kg00qf 17 4 clinical clinical JJ cord-022526-j9kg00qf 17 5 signs sign NNS cord-022526-j9kg00qf 17 6 of of IN cord-022526-j9kg00qf 17 7 systemic systemic JJ cord-022526-j9kg00qf 17 8 inflammation inflammation NN cord-022526-j9kg00qf 17 9 from from IN cord-022526-j9kg00qf 17 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 17 11 and and CC cord-022526-j9kg00qf 17 12 sepsis sepsis NN cord-022526-j9kg00qf 17 13 . . . cord-022526-j9kg00qf 18 1 One one PRP cord-022526-j9kg00qf 18 2 performs perform VBZ cord-022526-j9kg00qf 18 3 the the DT cord-022526-j9kg00qf 18 4 physical physical JJ cord-022526-j9kg00qf 18 5 examination examination NN cord-022526-j9kg00qf 18 6 of of IN cord-022526-j9kg00qf 18 7 the the DT cord-022526-j9kg00qf 18 8 abdomen abdomen NN cord-022526-j9kg00qf 18 9 primarily primarily RB cord-022526-j9kg00qf 18 10 by by IN cord-022526-j9kg00qf 18 11 auscultation auscultation NN cord-022526-j9kg00qf 18 12 , , , cord-022526-j9kg00qf 18 13 transabdominal transabdominal JJ cord-022526-j9kg00qf 18 14 ballottement ballottement NN cord-022526-j9kg00qf 18 15 , , , cord-022526-j9kg00qf 18 16 and and CC cord-022526-j9kg00qf 18 17 transrectal transrectal JJ cord-022526-j9kg00qf 18 18 palpation palpation NN cord-022526-j9kg00qf 18 19 . . . cord-022526-j9kg00qf 19 1 Abdominal abdominal JJ cord-022526-j9kg00qf 19 2 distention distention NN cord-022526-j9kg00qf 19 3 often often RB cord-022526-j9kg00qf 19 4 indicates indicate VBZ cord-022526-j9kg00qf 19 5 distention distention NN cord-022526-j9kg00qf 19 6 of of IN cord-022526-j9kg00qf 19 7 the the DT cord-022526-j9kg00qf 19 8 large large JJ cord-022526-j9kg00qf 19 9 intestine intestine NN cord-022526-j9kg00qf 19 10 ; ; : cord-022526-j9kg00qf 19 11 however however RB cord-022526-j9kg00qf 19 12 , , , cord-022526-j9kg00qf 19 13 small small JJ cord-022526-j9kg00qf 19 14 intestinal intestinal JJ cord-022526-j9kg00qf 19 15 distention distention NN cord-022526-j9kg00qf 19 16 also also RB cord-022526-j9kg00qf 19 17 can can MD cord-022526-j9kg00qf 19 18 cause cause VB cord-022526-j9kg00qf 19 19 visible visible JJ cord-022526-j9kg00qf 19 20 abdominal abdominal JJ cord-022526-j9kg00qf 19 21 distention distention NN cord-022526-j9kg00qf 19 22 if if IN cord-022526-j9kg00qf 19 23 a a DT cord-022526-j9kg00qf 19 24 large large JJ cord-022526-j9kg00qf 19 25 proportion proportion NN cord-022526-j9kg00qf 19 26 of of IN cord-022526-j9kg00qf 19 27 the the DT cord-022526-j9kg00qf 19 28 small small JJ cord-022526-j9kg00qf 19 29 intestine intestine NN cord-022526-j9kg00qf 19 30 is be VBZ cord-022526-j9kg00qf 19 31 involved involve VBN cord-022526-j9kg00qf 19 32 . . . cord-022526-j9kg00qf 20 1 One one PRP cord-022526-j9kg00qf 20 2 can can MD cord-022526-j9kg00qf 20 3 perform perform VB cord-022526-j9kg00qf 20 4 abdominal abdominal JJ cord-022526-j9kg00qf 20 5 palpation palpation NN cord-022526-j9kg00qf 20 6 in in IN cord-022526-j9kg00qf 20 7 neonatal neonatal JJ cord-022526-j9kg00qf 20 8 foals foal NNS cord-022526-j9kg00qf 20 9 ; ; : cord-022526-j9kg00qf 20 10 after after IN cord-022526-j9kg00qf 20 11 several several JJ cord-022526-j9kg00qf 20 12 weeks week NNS cord-022526-j9kg00qf 20 13 of of IN cord-022526-j9kg00qf 20 14 age age NN cord-022526-j9kg00qf 20 15 , , , cord-022526-j9kg00qf 20 16 motility motility NN cord-022526-j9kg00qf 20 17 ( ( -LRB- cord-022526-j9kg00qf 20 18 i.e. i.e. FW cord-022526-j9kg00qf 20 19 , , , cord-022526-j9kg00qf 20 20 α α NN cord-022526-j9kg00qf 20 21 2 2 CD cord-022526-j9kg00qf 20 22 -adrenergic -adrenergic JJ cord-022526-j9kg00qf 20 23 agonists agonist NNS cord-022526-j9kg00qf 20 24 such such JJ cord-022526-j9kg00qf 20 25 as as IN cord-022526-j9kg00qf 20 26 xylazine xylazine NN cord-022526-j9kg00qf 20 27 ) ) -RRB- cord-022526-j9kg00qf 20 28 . . . cord-022526-j9kg00qf 21 1 [ [ -LRB- cord-022526-j9kg00qf 21 2 2 2 LS cord-022526-j9kg00qf 21 3 ] ] -RRB- cord-022526-j9kg00qf 21 4 [ [ -LRB- cord-022526-j9kg00qf 21 5 3 3 CD cord-022526-j9kg00qf 21 6 ] ] -RRB- cord-022526-j9kg00qf 21 7 [ [ -LRB- cord-022526-j9kg00qf 21 8 4 4 CD cord-022526-j9kg00qf 21 9 ] ] -RRB- cord-022526-j9kg00qf 22 1 Absolute absolute JJ cord-022526-j9kg00qf 22 2 absence absence NN cord-022526-j9kg00qf 22 3 of of IN cord-022526-j9kg00qf 22 4 any any DT cord-022526-j9kg00qf 22 5 auscultable auscultable JJ cord-022526-j9kg00qf 22 6 borborygmi borborygmi NNP cord-022526-j9kg00qf 22 7 suggests suggest VBZ cord-022526-j9kg00qf 22 8 abnormal abnormal JJ cord-022526-j9kg00qf 22 9 motility motility NN cord-022526-j9kg00qf 22 10 and and CC cord-022526-j9kg00qf 22 11 indicates indicate VBZ cord-022526-j9kg00qf 22 12 ileus ileus NNP cord-022526-j9kg00qf 22 13 resulting result VBG cord-022526-j9kg00qf 22 14 from from IN cord-022526-j9kg00qf 22 15 a a DT cord-022526-j9kg00qf 22 16 serious serious JJ cord-022526-j9kg00qf 22 17 pathologic pathologic JJ cord-022526-j9kg00qf 22 18 condition condition NN cord-022526-j9kg00qf 22 19 but but CC cord-022526-j9kg00qf 22 20 is be VBZ cord-022526-j9kg00qf 22 21 not not RB cord-022526-j9kg00qf 22 22 specific specific JJ cord-022526-j9kg00qf 22 23 to to IN cord-022526-j9kg00qf 22 24 any any DT cord-022526-j9kg00qf 22 25 segment segment NN cord-022526-j9kg00qf 22 26 of of IN cord-022526-j9kg00qf 22 27 the the DT cord-022526-j9kg00qf 22 28 intestine intestine NN cord-022526-j9kg00qf 22 29 . . . cord-022526-j9kg00qf 23 1 3 3 CD cord-022526-j9kg00qf 23 2 , , , cord-022526-j9kg00qf 23 3 5 5 CD cord-022526-j9kg00qf 24 1 If if IN cord-022526-j9kg00qf 24 2 borborygmi borborygmi NNP cord-022526-j9kg00qf 24 3 are be VBP cord-022526-j9kg00qf 24 4 audible audible JJ cord-022526-j9kg00qf 24 5 but but CC cord-022526-j9kg00qf 24 6 progressive progressive JJ cord-022526-j9kg00qf 24 7 sounds sound NNS cord-022526-j9kg00qf 24 8 are be VBP cord-022526-j9kg00qf 24 9 not not RB cord-022526-j9kg00qf 24 10 detectable detectable JJ cord-022526-j9kg00qf 24 11 , , , cord-022526-j9kg00qf 24 12 determining determine VBG cord-022526-j9kg00qf 24 13 whether whether IN cord-022526-j9kg00qf 24 14 a a DT cord-022526-j9kg00qf 24 15 significant significant JJ cord-022526-j9kg00qf 24 16 abnormality abnormality NN cord-022526-j9kg00qf 24 17 exists exist VBZ cord-022526-j9kg00qf 24 18 is be VBZ cord-022526-j9kg00qf 24 19 difficult difficult JJ cord-022526-j9kg00qf 24 20 . . . cord-022526-j9kg00qf 25 1 5 5 CD cord-022526-j9kg00qf 25 2 Borborygmi Borborygmi NNP cord-022526-j9kg00qf 25 3 heard hear VBD cord-022526-j9kg00qf 25 4 more more RBR cord-022526-j9kg00qf 25 5 frequently frequently RB cord-022526-j9kg00qf 25 6 than than IN cord-022526-j9kg00qf 25 7 normal normal JJ cord-022526-j9kg00qf 25 8 may may MD cord-022526-j9kg00qf 25 9 result result VB cord-022526-j9kg00qf 25 10 from from IN cord-022526-j9kg00qf 25 11 increased increase VBN cord-022526-j9kg00qf 25 12 motility motility NN cord-022526-j9kg00qf 25 13 following follow VBG cord-022526-j9kg00qf 25 14 feeding feeding NN cord-022526-j9kg00qf 25 15 ; ; : cord-022526-j9kg00qf 25 16 from from IN cord-022526-j9kg00qf 25 17 excessive excessive JJ cord-022526-j9kg00qf 25 18 stimulation stimulation NN cord-022526-j9kg00qf 25 19 from from IN cord-022526-j9kg00qf 25 20 irritation irritation NN cord-022526-j9kg00qf 25 21 , , , cord-022526-j9kg00qf 25 22 distention distention NN cord-022526-j9kg00qf 25 23 , , , cord-022526-j9kg00qf 25 24 or or CC cord-022526-j9kg00qf 25 25 inflammation inflammation NN cord-022526-j9kg00qf 25 26 ; ; : cord-022526-j9kg00qf 25 27 or or CC cord-022526-j9kg00qf 25 28 after after IN cord-022526-j9kg00qf 25 29 administration administration NN cord-022526-j9kg00qf 25 30 of of IN cord-022526-j9kg00qf 25 31 parasympathomimetic parasympathomimetic JJ cord-022526-j9kg00qf 25 32 drugs drug NNS cord-022526-j9kg00qf 25 33 such such JJ cord-022526-j9kg00qf 25 34 as as IN cord-022526-j9kg00qf 25 35 neostigmine neostigmine NNP cord-022526-j9kg00qf 25 36 . . . cord-022526-j9kg00qf 26 1 Large large JJ cord-022526-j9kg00qf 26 2 intestinal intestinal JJ cord-022526-j9kg00qf 26 3 motility motility NN cord-022526-j9kg00qf 26 4 increases increase NNS cord-022526-j9kg00qf 26 5 in in IN cord-022526-j9kg00qf 26 6 the the DT cord-022526-j9kg00qf 26 7 early early JJ cord-022526-j9kg00qf 26 8 stages stage NNS cord-022526-j9kg00qf 26 9 of of IN cord-022526-j9kg00qf 26 10 intestinal intestinal JJ cord-022526-j9kg00qf 26 11 distention distention NN cord-022526-j9kg00qf 26 12 regardless regardless RB cord-022526-j9kg00qf 26 13 of of IN cord-022526-j9kg00qf 26 14 the the DT cord-022526-j9kg00qf 26 15 site site NN cord-022526-j9kg00qf 26 16 . . . cord-022526-j9kg00qf 27 1 6 6 CD cord-022526-j9kg00qf 28 1 Mild mild JJ cord-022526-j9kg00qf 28 2 inflammation inflammation NN cord-022526-j9kg00qf 28 3 or or CC cord-022526-j9kg00qf 28 4 irritation irritation NN cord-022526-j9kg00qf 28 5 of of IN cord-022526-j9kg00qf 28 6 the the DT cord-022526-j9kg00qf 28 7 large large JJ cord-022526-j9kg00qf 28 8 intestinal intestinal JJ cord-022526-j9kg00qf 28 9 mucosa mucosa NN cord-022526-j9kg00qf 28 10 also also RB cord-022526-j9kg00qf 28 11 can can MD cord-022526-j9kg00qf 28 12 stimulate stimulate VB cord-022526-j9kg00qf 28 13 motility motility NN cord-022526-j9kg00qf 28 14 . . . cord-022526-j9kg00qf 29 1 3 3 LS cord-022526-j9kg00qf 30 1 Parasympathomimetic parasympathomimetic JJ cord-022526-j9kg00qf 30 2 drugs drug NNS cord-022526-j9kg00qf 30 3 stimulate stimulate VBP cord-022526-j9kg00qf 30 4 contractions contraction NNS cord-022526-j9kg00qf 30 5 and and CC cord-022526-j9kg00qf 30 6 auscultable auscultable JJ cord-022526-j9kg00qf 30 7 borborygmi borborygmi NN cord-022526-j9kg00qf 30 8 in in IN cord-022526-j9kg00qf 30 9 the the DT cord-022526-j9kg00qf 30 10 large large JJ cord-022526-j9kg00qf 30 11 intestine intestine NN cord-022526-j9kg00qf 30 12 ; ; : cord-022526-j9kg00qf 30 13 however however RB cord-022526-j9kg00qf 30 14 , , , cord-022526-j9kg00qf 30 15 an an DT cord-022526-j9kg00qf 30 16 increase increase NN cord-022526-j9kg00qf 30 17 in in IN cord-022526-j9kg00qf 30 18 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 30 19 tone tone NN cord-022526-j9kg00qf 30 20 may may MD cord-022526-j9kg00qf 30 21 result result VB cord-022526-j9kg00qf 30 22 in in IN cord-022526-j9kg00qf 30 23 segmental segmental JJ cord-022526-j9kg00qf 30 24 contractions contraction NNS cord-022526-j9kg00qf 30 25 , , , cord-022526-j9kg00qf 30 26 which which WDT cord-022526-j9kg00qf 30 27 actually actually RB cord-022526-j9kg00qf 30 28 inhibit inhibit VBP cord-022526-j9kg00qf 30 29 progressive progressive JJ cord-022526-j9kg00qf 30 30 motility motility NN cord-022526-j9kg00qf 30 31 . . . cord-022526-j9kg00qf 31 1 2 2 LS cord-022526-j9kg00qf 32 1 One one PRP cord-022526-j9kg00qf 32 2 can can MD cord-022526-j9kg00qf 32 3 detect detect VB cord-022526-j9kg00qf 32 4 sand sand NN cord-022526-j9kg00qf 32 5 or or CC cord-022526-j9kg00qf 32 6 gravel gravel NN cord-022526-j9kg00qf 32 7 in in IN cord-022526-j9kg00qf 32 8 the the DT cord-022526-j9kg00qf 32 9 large large JJ cord-022526-j9kg00qf 32 10 intestinal intestinal JJ cord-022526-j9kg00qf 32 11 ingesta ingesta NNS cord-022526-j9kg00qf 32 12 by by IN cord-022526-j9kg00qf 32 13 auscultation auscultation NN cord-022526-j9kg00qf 32 14 behind behind IN cord-022526-j9kg00qf 32 15 the the DT cord-022526-j9kg00qf 32 16 xiphoid xiphoid NN cord-022526-j9kg00qf 32 17 process process NN cord-022526-j9kg00qf 32 18 . . . cord-022526-j9kg00qf 33 1 One one PRP cord-022526-j9kg00qf 33 2 can can MD cord-022526-j9kg00qf 33 3 hear hear VB cord-022526-j9kg00qf 33 4 sand sand NN cord-022526-j9kg00qf 33 5 or or CC cord-022526-j9kg00qf 33 6 gravel gravel NN cord-022526-j9kg00qf 33 7 particles particle NNS cord-022526-j9kg00qf 33 8 grinding grind VBG cord-022526-j9kg00qf 33 9 together together RB cord-022526-j9kg00qf 33 10 during during IN cord-022526-j9kg00qf 33 11 progressive progressive JJ cord-022526-j9kg00qf 33 12 contractions contraction NNS cord-022526-j9kg00qf 33 13 of of IN cord-022526-j9kg00qf 33 14 the the DT cord-022526-j9kg00qf 33 15 ascending ascend VBG cord-022526-j9kg00qf 33 16 colon colon NN cord-022526-j9kg00qf 33 17 . . . cord-022526-j9kg00qf 34 1 The the DT cord-022526-j9kg00qf 34 2 presence presence NN cord-022526-j9kg00qf 34 3 of of IN cord-022526-j9kg00qf 34 4 sand sand NN cord-022526-j9kg00qf 34 5 in in IN cord-022526-j9kg00qf 34 6 the the DT cord-022526-j9kg00qf 34 7 ingesta ingesta NNS cord-022526-j9kg00qf 34 8 becomes become VBZ cord-022526-j9kg00qf 34 9 clinically clinically RB cord-022526-j9kg00qf 34 10 detectable detectable JJ cord-022526-j9kg00qf 34 11 by by IN cord-022526-j9kg00qf 34 12 auscultation auscultation NN cord-022526-j9kg00qf 34 13 or or CC cord-022526-j9kg00qf 34 14 fecal fecal JJ cord-022526-j9kg00qf 34 15 sedimentation sedimentation NN cord-022526-j9kg00qf 34 16 before before IN cord-022526-j9kg00qf 34 17 the the DT cord-022526-j9kg00qf 34 18 amount amount NN cord-022526-j9kg00qf 34 19 of of IN cord-022526-j9kg00qf 34 20 sand sand NN cord-022526-j9kg00qf 34 21 is be VBZ cord-022526-j9kg00qf 34 22 enough enough JJ cord-022526-j9kg00qf 34 23 to to TO cord-022526-j9kg00qf 34 24 produce produce VB cord-022526-j9kg00qf 34 25 clinical clinical JJ cord-022526-j9kg00qf 34 26 signs sign NNS cord-022526-j9kg00qf 34 27 of of IN cord-022526-j9kg00qf 34 28 pain pain NN cord-022526-j9kg00qf 34 29 or or CC cord-022526-j9kg00qf 34 30 irritation irritation NN cord-022526-j9kg00qf 34 31 ( ( -LRB- cord-022526-j9kg00qf 34 32 diarrhea diarrhea NN cord-022526-j9kg00qf 34 33 ) ) -RRB- cord-022526-j9kg00qf 34 34 . . . cord-022526-j9kg00qf 35 1 7 7 CD cord-022526-j9kg00qf 36 1 If if IN cord-022526-j9kg00qf 36 2 progressive progressive JJ cord-022526-j9kg00qf 36 3 contractions contraction NNS cord-022526-j9kg00qf 36 4 are be VBP cord-022526-j9kg00qf 36 5 audible audible JJ cord-022526-j9kg00qf 36 6 without without IN cord-022526-j9kg00qf 36 7 hearing hear VBG cord-022526-j9kg00qf 36 8 sand sand NN cord-022526-j9kg00qf 36 9 sounds sound NNS cord-022526-j9kg00qf 36 10 , , , cord-022526-j9kg00qf 36 11 clinically clinically RB cord-022526-j9kg00qf 36 12 important important JJ cord-022526-j9kg00qf 36 13 quantities quantity NNS cord-022526-j9kg00qf 36 14 of of IN cord-022526-j9kg00qf 36 15 sand sand NN cord-022526-j9kg00qf 36 16 likely likely RB cord-022526-j9kg00qf 36 17 are be VBP cord-022526-j9kg00qf 36 18 not not RB cord-022526-j9kg00qf 36 19 present present JJ cord-022526-j9kg00qf 36 20 . . . cord-022526-j9kg00qf 37 1 If if IN cord-022526-j9kg00qf 37 2 the the DT cord-022526-j9kg00qf 37 3 frequency frequency NN cord-022526-j9kg00qf 37 4 of of IN cord-022526-j9kg00qf 37 5 progressive progressive JJ cord-022526-j9kg00qf 37 6 contractions contraction NNS cord-022526-j9kg00qf 37 7 is be VBZ cord-022526-j9kg00qf 37 8 low low JJ cord-022526-j9kg00qf 37 9 or or CC cord-022526-j9kg00qf 37 10 absent absent JJ cord-022526-j9kg00qf 37 11 , , , cord-022526-j9kg00qf 37 12 detecting detect VBG cord-022526-j9kg00qf 37 13 sand sand NN cord-022526-j9kg00qf 37 14 by by IN cord-022526-j9kg00qf 37 15 auscultation auscultation NN cord-022526-j9kg00qf 37 16 is be VBZ cord-022526-j9kg00qf 37 17 difficult difficult JJ cord-022526-j9kg00qf 37 18 . . . cord-022526-j9kg00qf 38 1 Percussion percussion NN cord-022526-j9kg00qf 38 2 of of IN cord-022526-j9kg00qf 38 3 the the DT cord-022526-j9kg00qf 38 4 abdomen abdomen NN cord-022526-j9kg00qf 38 5 during during IN cord-022526-j9kg00qf 38 6 auscultation auscultation NN cord-022526-j9kg00qf 38 7 can can MD cord-022526-j9kg00qf 38 8 reveal reveal VB cord-022526-j9kg00qf 38 9 gas gas NN cord-022526-j9kg00qf 38 10 in in IN cord-022526-j9kg00qf 38 11 the the DT cord-022526-j9kg00qf 38 12 large large JJ cord-022526-j9kg00qf 38 13 intestine intestine NN cord-022526-j9kg00qf 38 14 . . . cord-022526-j9kg00qf 39 1 The the DT cord-022526-j9kg00qf 39 2 characteristic characteristic JJ cord-022526-j9kg00qf 39 3 ping ping NN cord-022526-j9kg00qf 39 4 produced produce VBN cord-022526-j9kg00qf 39 5 by by IN cord-022526-j9kg00qf 39 6 simultaneous simultaneous JJ cord-022526-j9kg00qf 39 7 digital digital JJ cord-022526-j9kg00qf 39 8 percussion percussion NN cord-022526-j9kg00qf 39 9 and and CC cord-022526-j9kg00qf 39 10 auscultation auscultation NN cord-022526-j9kg00qf 39 11 over over IN cord-022526-j9kg00qf 39 12 a a DT cord-022526-j9kg00qf 39 13 gas gas NN cord-022526-j9kg00qf 39 14 - - HYPH cord-022526-j9kg00qf 39 15 filled fill VBN cord-022526-j9kg00qf 39 16 viscus viscus NN cord-022526-j9kg00qf 39 17 often often RB cord-022526-j9kg00qf 39 18 is be VBZ cord-022526-j9kg00qf 39 19 associated associate VBN cord-022526-j9kg00qf 39 20 with with IN cord-022526-j9kg00qf 39 21 abnormal abnormal JJ cord-022526-j9kg00qf 39 22 accumulation accumulation NN cord-022526-j9kg00qf 39 23 of of IN cord-022526-j9kg00qf 39 24 gas gas NN cord-022526-j9kg00qf 39 25 under under IN cord-022526-j9kg00qf 39 26 pressure pressure NN cord-022526-j9kg00qf 39 27 . . . cord-022526-j9kg00qf 40 1 This this DT cord-022526-j9kg00qf 40 2 technique technique NN cord-022526-j9kg00qf 40 3 is be VBZ cord-022526-j9kg00qf 40 4 particularly particularly RB cord-022526-j9kg00qf 40 5 useful useful JJ cord-022526-j9kg00qf 40 6 in in IN cord-022526-j9kg00qf 40 7 foals foal NNS cord-022526-j9kg00qf 40 8 , , , cord-022526-j9kg00qf 40 9 ponies pony NNS cord-022526-j9kg00qf 40 10 , , , cord-022526-j9kg00qf 40 11 and and CC cord-022526-j9kg00qf 40 12 Miniature miniature JJ cord-022526-j9kg00qf 40 13 horses horse NNS cord-022526-j9kg00qf 40 14 because because IN cord-022526-j9kg00qf 40 15 of of IN cord-022526-j9kg00qf 40 16 the the DT cord-022526-j9kg00qf 40 17 limitations limitation NNS cord-022526-j9kg00qf 40 18 of of IN cord-022526-j9kg00qf 40 19 palpation palpation NN cord-022526-j9kg00qf 40 20 per per IN cord-022526-j9kg00qf 40 21 rectum rectum NN cord-022526-j9kg00qf 40 22 . . . cord-022526-j9kg00qf 41 1 One one PRP cord-022526-j9kg00qf 41 2 can can MD cord-022526-j9kg00qf 41 3 use use VB cord-022526-j9kg00qf 41 4 transabdominal transabdominal JJ cord-022526-j9kg00qf 41 5 ballottement ballottement NN cord-022526-j9kg00qf 41 6 to to TO cord-022526-j9kg00qf 41 7 detect detect VB cord-022526-j9kg00qf 41 8 large large JJ cord-022526-j9kg00qf 41 9 , , , cord-022526-j9kg00qf 41 10 firm firm JJ cord-022526-j9kg00qf 41 11 masses masse NNS cord-022526-j9kg00qf 41 12 or or CC cord-022526-j9kg00qf 41 13 an an DT cord-022526-j9kg00qf 41 14 abnormal abnormal JJ cord-022526-j9kg00qf 41 15 volume volume NN cord-022526-j9kg00qf 41 16 of of IN cord-022526-j9kg00qf 41 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 41 18 fluid fluid NN cord-022526-j9kg00qf 41 19 . . . cord-022526-j9kg00qf 42 1 The the DT cord-022526-j9kg00qf 42 2 usefulness usefulness NN cord-022526-j9kg00qf 42 3 of of IN cord-022526-j9kg00qf 42 4 this this DT cord-022526-j9kg00qf 42 5 technique technique NN cord-022526-j9kg00qf 42 6 is be VBZ cord-022526-j9kg00qf 42 7 usually usually RB cord-022526-j9kg00qf 42 8 limited limit VBN cord-022526-j9kg00qf 42 9 to to IN cord-022526-j9kg00qf 42 10 animals animal NNS cord-022526-j9kg00qf 42 11 too too RB cord-022526-j9kg00qf 42 12 small small JJ cord-022526-j9kg00qf 42 13 to to TO cord-022526-j9kg00qf 42 14 palpate palpate VB cord-022526-j9kg00qf 42 15 per per IN cord-022526-j9kg00qf 42 16 rectum rectum NN cord-022526-j9kg00qf 42 17 . . . cord-022526-j9kg00qf 43 1 One one PRP cord-022526-j9kg00qf 43 2 can can MD cord-022526-j9kg00qf 43 3 detect detect VB cord-022526-j9kg00qf 43 4 soft soft JJ cord-022526-j9kg00qf 43 5 tissue tissue NN cord-022526-j9kg00qf 43 6 masses masse NNS cord-022526-j9kg00qf 43 7 or or CC cord-022526-j9kg00qf 43 8 fetuses fetus NNS cord-022526-j9kg00qf 43 9 by by IN cord-022526-j9kg00qf 43 10 bumping bump VBG cord-022526-j9kg00qf 43 11 the the DT cord-022526-j9kg00qf 43 12 structures structure NNS cord-022526-j9kg00qf 43 13 with with IN cord-022526-j9kg00qf 43 14 a a DT cord-022526-j9kg00qf 43 15 hand hand NN cord-022526-j9kg00qf 43 16 or or CC cord-022526-j9kg00qf 43 17 fist fist NN cord-022526-j9kg00qf 43 18 . . . cord-022526-j9kg00qf 44 1 If if IN cord-022526-j9kg00qf 44 2 excessive excessive JJ cord-022526-j9kg00qf 44 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 44 4 fluid fluid NN cord-022526-j9kg00qf 44 5 is be VBZ cord-022526-j9kg00qf 44 6 present present JJ cord-022526-j9kg00qf 44 7 , , , cord-022526-j9kg00qf 44 8 one one PRP cord-022526-j9kg00qf 44 9 can can MD cord-022526-j9kg00qf 44 10 generate generate VB cord-022526-j9kg00qf 44 11 a a DT cord-022526-j9kg00qf 44 12 fluid fluid JJ cord-022526-j9kg00qf 44 13 wave wave NN cord-022526-j9kg00qf 44 14 by by IN cord-022526-j9kg00qf 44 15 ballottement ballottement NNP cord-022526-j9kg00qf 44 16 ; ; : cord-022526-j9kg00qf 44 17 however however RB cord-022526-j9kg00qf 44 18 , , , cord-022526-j9kg00qf 44 19 this this DT cord-022526-j9kg00qf 44 20 technique technique NN cord-022526-j9kg00qf 44 21 is be VBZ cord-022526-j9kg00qf 44 22 not not RB cord-022526-j9kg00qf 44 23 as as RB cord-022526-j9kg00qf 44 24 useful useful JJ cord-022526-j9kg00qf 44 25 in in IN cord-022526-j9kg00qf 44 26 horses horse NNS cord-022526-j9kg00qf 44 27 older old JJR cord-022526-j9kg00qf 44 28 than than IN cord-022526-j9kg00qf 44 29 4 4 CD cord-022526-j9kg00qf 44 30 weeks week NNS cord-022526-j9kg00qf 44 31 because because IN cord-022526-j9kg00qf 44 32 the the DT cord-022526-j9kg00qf 44 33 abdominal abdominal JJ cord-022526-j9kg00qf 44 34 wall wall NN cord-022526-j9kg00qf 44 35 is be VBZ cord-022526-j9kg00qf 44 36 rigid rigid JJ cord-022526-j9kg00qf 44 37 . . . cord-022526-j9kg00qf 45 1 Transrectal transrectal JJ cord-022526-j9kg00qf 45 2 palpation palpation NN cord-022526-j9kg00qf 45 3 is be VBZ cord-022526-j9kg00qf 45 4 the the DT cord-022526-j9kg00qf 45 5 most most RBS cord-022526-j9kg00qf 45 6 specific specific JJ cord-022526-j9kg00qf 45 7 physical physical JJ cord-022526-j9kg00qf 45 8 examination examination NN cord-022526-j9kg00qf 45 9 technique technique NN cord-022526-j9kg00qf 45 10 for for IN cord-022526-j9kg00qf 45 11 investigation investigation NN cord-022526-j9kg00qf 45 12 of of IN cord-022526-j9kg00qf 45 13 intestinal intestinal JJ cord-022526-j9kg00qf 45 14 disease disease NN cord-022526-j9kg00qf 45 15 and and CC cord-022526-j9kg00qf 45 16 is be VBZ cord-022526-j9kg00qf 45 17 particularly particularly RB cord-022526-j9kg00qf 45 18 valuable valuable JJ cord-022526-j9kg00qf 45 19 when when WRB cord-022526-j9kg00qf 45 20 evaluating evaluate VBG cord-022526-j9kg00qf 45 21 obstructive obstructive JJ cord-022526-j9kg00qf 45 22 diseases disease NNS cord-022526-j9kg00qf 45 23 . . . cord-022526-j9kg00qf 46 1 8 8 CD cord-022526-j9kg00qf 46 2 , , , cord-022526-j9kg00qf 46 3 9 9 CD cord-022526-j9kg00qf 47 1 The the DT cord-022526-j9kg00qf 47 2 primary primary JJ cord-022526-j9kg00qf 47 3 objectives objective NNS cord-022526-j9kg00qf 47 4 of of IN cord-022526-j9kg00qf 47 5 transrectal transrectal JJ cord-022526-j9kg00qf 47 6 palpation palpation NN cord-022526-j9kg00qf 47 7 are be VBP cord-022526-j9kg00qf 47 8 to to TO cord-022526-j9kg00qf 47 9 assess assess VB cord-022526-j9kg00qf 47 10 the the DT cord-022526-j9kg00qf 47 11 size size NN cord-022526-j9kg00qf 47 12 , , , cord-022526-j9kg00qf 47 13 consistency consistency NN cord-022526-j9kg00qf 47 14 , , , cord-022526-j9kg00qf 47 15 and and CC cord-022526-j9kg00qf 47 16 position position NN cord-022526-j9kg00qf 47 17 of of IN cord-022526-j9kg00qf 47 18 the the DT cord-022526-j9kg00qf 47 19 segments segment NNS cord-022526-j9kg00qf 47 20 of of IN cord-022526-j9kg00qf 47 21 the the DT cord-022526-j9kg00qf 47 22 large large JJ cord-022526-j9kg00qf 47 23 intestine intestine NN cord-022526-j9kg00qf 47 24 ; ; : cord-022526-j9kg00qf 47 25 to to TO cord-022526-j9kg00qf 47 26 determine determine VB cord-022526-j9kg00qf 47 27 the the DT cord-022526-j9kg00qf 47 28 presence presence NN cord-022526-j9kg00qf 47 29 of of IN cord-022526-j9kg00qf 47 30 any any DT cord-022526-j9kg00qf 47 31 small small JJ cord-022526-j9kg00qf 47 32 intestinal intestinal JJ cord-022526-j9kg00qf 47 33 distention distention NN cord-022526-j9kg00qf 47 34 ; ; : cord-022526-j9kg00qf 47 35 and and CC cord-022526-j9kg00qf 47 36 to to TO cord-022526-j9kg00qf 47 37 detect detect VB cord-022526-j9kg00qf 47 38 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 47 39 masses masse NNS cord-022526-j9kg00qf 47 40 . . . cord-022526-j9kg00qf 48 1 Evaluation evaluation NN cord-022526-j9kg00qf 48 2 of of IN cord-022526-j9kg00qf 48 3 the the DT cord-022526-j9kg00qf 48 4 wall wall NN cord-022526-j9kg00qf 48 5 thickness thickness NN cord-022526-j9kg00qf 48 6 and and CC cord-022526-j9kg00qf 48 7 texture texture NN cord-022526-j9kg00qf 48 8 and and CC cord-022526-j9kg00qf 48 9 the the DT cord-022526-j9kg00qf 48 10 mesenteric mesenteric JJ cord-022526-j9kg00qf 48 11 structures structure NNS cord-022526-j9kg00qf 48 12 ( ( -LRB- cord-022526-j9kg00qf 48 13 blood blood NN cord-022526-j9kg00qf 48 14 and and CC cord-022526-j9kg00qf 48 15 lymphatic lymphatic JJ cord-022526-j9kg00qf 48 16 vessels vessel NNS cord-022526-j9kg00qf 48 17 and and CC cord-022526-j9kg00qf 48 18 lymph lymph NN cord-022526-j9kg00qf 48 19 nodes node NNS cord-022526-j9kg00qf 48 20 ) ) -RRB- cord-022526-j9kg00qf 48 21 also also RB cord-022526-j9kg00qf 48 22 may may MD cord-022526-j9kg00qf 48 23 aid aid VB cord-022526-j9kg00qf 48 24 in in IN cord-022526-j9kg00qf 48 25 diagnosis diagnosis NN cord-022526-j9kg00qf 48 26 of of IN cord-022526-j9kg00qf 48 27 large large JJ cord-022526-j9kg00qf 48 28 intestinal intestinal JJ cord-022526-j9kg00qf 48 29 disease disease NN cord-022526-j9kg00qf 48 30 . . . cord-022526-j9kg00qf 49 1 The the DT cord-022526-j9kg00qf 49 2 interpretation interpretation NN cord-022526-j9kg00qf 49 3 of of IN cord-022526-j9kg00qf 49 4 transrectal transrectal JJ cord-022526-j9kg00qf 49 5 palpation palpation NN cord-022526-j9kg00qf 49 6 findings finding NNS cord-022526-j9kg00qf 49 7 in in IN cord-022526-j9kg00qf 49 8 light light NN cord-022526-j9kg00qf 49 9 of of IN cord-022526-j9kg00qf 49 10 clinical clinical JJ cord-022526-j9kg00qf 49 11 signs sign NNS cord-022526-j9kg00qf 49 12 and and CC cord-022526-j9kg00qf 49 13 laboratory laboratory NN cord-022526-j9kg00qf 49 14 results result NNS cord-022526-j9kg00qf 49 15 is be VBZ cord-022526-j9kg00qf 49 16 an an DT cord-022526-j9kg00qf 49 17 important important JJ cord-022526-j9kg00qf 49 18 diagnostic diagnostic JJ cord-022526-j9kg00qf 49 19 aid aid NN cord-022526-j9kg00qf 49 20 for for IN cord-022526-j9kg00qf 49 21 developing develop VBG cord-022526-j9kg00qf 49 22 appropriate appropriate JJ cord-022526-j9kg00qf 49 23 treatment treatment NN cord-022526-j9kg00qf 49 24 strategies strategy NNS cord-022526-j9kg00qf 49 25 for for IN cord-022526-j9kg00qf 49 26 intestinal intestinal JJ cord-022526-j9kg00qf 49 27 diseases disease NNS cord-022526-j9kg00qf 49 28 manifested manifest VBN cord-022526-j9kg00qf 49 29 by by IN cord-022526-j9kg00qf 49 30 abdominal abdominal JJ cord-022526-j9kg00qf 49 31 pain pain NN cord-022526-j9kg00qf 49 32 . . . cord-022526-j9kg00qf 50 1 Enlargement enlargement NN cord-022526-j9kg00qf 50 2 of of IN cord-022526-j9kg00qf 50 3 one one CD cord-022526-j9kg00qf 50 4 or or CC cord-022526-j9kg00qf 50 5 more more JJR cord-022526-j9kg00qf 50 6 segments segment NNS cord-022526-j9kg00qf 50 7 of of IN cord-022526-j9kg00qf 50 8 large large JJ cord-022526-j9kg00qf 50 9 intestine intestine NN cord-022526-j9kg00qf 50 10 detected detect VBN cord-022526-j9kg00qf 50 11 by by IN cord-022526-j9kg00qf 50 12 transrectal transrectal JJ cord-022526-j9kg00qf 50 13 palpation palpation NN cord-022526-j9kg00qf 50 14 provides provide VBZ cord-022526-j9kg00qf 50 15 evidence evidence NN cord-022526-j9kg00qf 50 16 of of IN cord-022526-j9kg00qf 50 17 obstruction obstruction NN cord-022526-j9kg00qf 50 18 at at IN cord-022526-j9kg00qf 50 19 or or CC cord-022526-j9kg00qf 50 20 distal distal JJ cord-022526-j9kg00qf 50 21 to to IN cord-022526-j9kg00qf 50 22 the the DT cord-022526-j9kg00qf 50 23 enlarged enlarged JJ cord-022526-j9kg00qf 50 24 segment segment NN cord-022526-j9kg00qf 50 25 . . . cord-022526-j9kg00qf 51 1 By by IN cord-022526-j9kg00qf 51 2 systematically systematically RB cord-022526-j9kg00qf 51 3 evaluating evaluate VBG cord-022526-j9kg00qf 51 4 each each DT cord-022526-j9kg00qf 51 5 segment segment NN cord-022526-j9kg00qf 51 6 , , , cord-022526-j9kg00qf 51 7 one one PRP cord-022526-j9kg00qf 51 8 may may MD cord-022526-j9kg00qf 51 9 determine determine VB cord-022526-j9kg00qf 51 10 the the DT cord-022526-j9kg00qf 51 11 site site NN cord-022526-j9kg00qf 51 12 of of IN cord-022526-j9kg00qf 51 13 obstruction obstruction NN cord-022526-j9kg00qf 51 14 . . . cord-022526-j9kg00qf 52 1 Obstruction obstruction NN cord-022526-j9kg00qf 52 2 of of IN cord-022526-j9kg00qf 52 3 the the DT cord-022526-j9kg00qf 52 4 pelvic pelvic JJ cord-022526-j9kg00qf 52 5 flexure flexure NN cord-022526-j9kg00qf 52 6 , , , cord-022526-j9kg00qf 52 7 for for IN cord-022526-j9kg00qf 52 8 instance instance NN cord-022526-j9kg00qf 52 9 , , , cord-022526-j9kg00qf 52 10 results result NNS cord-022526-j9kg00qf 52 11 in in IN cord-022526-j9kg00qf 52 12 enlargement enlargement NN cord-022526-j9kg00qf 52 13 of of IN cord-022526-j9kg00qf 52 14 the the DT cord-022526-j9kg00qf 52 15 pelvic pelvic JJ cord-022526-j9kg00qf 52 16 flexure flexure NN cord-022526-j9kg00qf 52 17 and and CC cord-022526-j9kg00qf 52 18 ventral ventral JJ cord-022526-j9kg00qf 52 19 colon colon NN cord-022526-j9kg00qf 52 20 , , , cord-022526-j9kg00qf 52 21 but but CC cord-022526-j9kg00qf 52 22 the the DT cord-022526-j9kg00qf 52 23 dorsal dorsal NN cord-022526-j9kg00qf 52 24 and and CC cord-022526-j9kg00qf 52 25 descending descend VBG cord-022526-j9kg00qf 52 26 colons colon NNS cord-022526-j9kg00qf 52 27 are be VBP cord-022526-j9kg00qf 52 28 of of IN cord-022526-j9kg00qf 52 29 normal normal JJ cord-022526-j9kg00qf 52 30 size size NN cord-022526-j9kg00qf 52 31 . . . cord-022526-j9kg00qf 53 1 Enlargement enlargement NN cord-022526-j9kg00qf 53 2 of of IN cord-022526-j9kg00qf 53 3 a a DT cord-022526-j9kg00qf 53 4 segment segment NN cord-022526-j9kg00qf 53 5 of of IN cord-022526-j9kg00qf 53 6 the the DT cord-022526-j9kg00qf 53 7 large large JJ cord-022526-j9kg00qf 53 8 intestine intestine NN cord-022526-j9kg00qf 53 9 usually usually RB cord-022526-j9kg00qf 53 10 is be VBZ cord-022526-j9kg00qf 53 11 accompanied accompany VBN cord-022526-j9kg00qf 53 12 by by IN cord-022526-j9kg00qf 53 13 abnormal abnormal JJ cord-022526-j9kg00qf 53 14 consistency consistency NN cord-022526-j9kg00qf 53 15 of of IN cord-022526-j9kg00qf 53 16 the the DT cord-022526-j9kg00qf 53 17 contents content NNS cord-022526-j9kg00qf 53 18 . . . cord-022526-j9kg00qf 54 1 One one PRP cord-022526-j9kg00qf 54 2 may may MD cord-022526-j9kg00qf 54 3 distinguish distinguish VB cord-022526-j9kg00qf 54 4 accumulation accumulation NN cord-022526-j9kg00qf 54 5 of of IN cord-022526-j9kg00qf 54 6 gas gas NN cord-022526-j9kg00qf 54 7 , , , cord-022526-j9kg00qf 54 8 fluid fluid NN cord-022526-j9kg00qf 54 9 , , , cord-022526-j9kg00qf 54 10 or or CC cord-022526-j9kg00qf 54 11 ingesta ingesta JJ cord-022526-j9kg00qf 54 12 and and CC cord-022526-j9kg00qf 54 13 may may MD cord-022526-j9kg00qf 54 14 detect detect VB cord-022526-j9kg00qf 54 15 foreign foreign JJ cord-022526-j9kg00qf 54 16 bodies body NNS cord-022526-j9kg00qf 54 17 in in IN cord-022526-j9kg00qf 54 18 palpable palpable JJ cord-022526-j9kg00qf 54 19 segments segment NNS cord-022526-j9kg00qf 54 20 . . . cord-022526-j9kg00qf 55 1 Accumulation accumulation NN cord-022526-j9kg00qf 55 2 of of IN cord-022526-j9kg00qf 55 3 gas gas NN cord-022526-j9kg00qf 55 4 and and CC cord-022526-j9kg00qf 55 5 fluid fluid NN cord-022526-j9kg00qf 55 6 infers infer VBZ cord-022526-j9kg00qf 55 7 complete complete JJ cord-022526-j9kg00qf 55 8 and and CC cord-022526-j9kg00qf 55 9 acute acute JJ cord-022526-j9kg00qf 55 10 obstruction obstruction NN cord-022526-j9kg00qf 55 11 , , , cord-022526-j9kg00qf 55 12 whereas whereas IN cord-022526-j9kg00qf 55 13 accumulation accumulation NN cord-022526-j9kg00qf 55 14 of of IN cord-022526-j9kg00qf 55 15 ingesta ingesta NNP cord-022526-j9kg00qf 55 16 infers infer VBZ cord-022526-j9kg00qf 55 17 chronic chronic JJ cord-022526-j9kg00qf 55 18 and and CC cord-022526-j9kg00qf 55 19 incomplete incomplete JJ cord-022526-j9kg00qf 55 20 obstruction obstruction NN cord-022526-j9kg00qf 55 21 . . . cord-022526-j9kg00qf 56 1 Accumulation accumulation NN cord-022526-j9kg00qf 56 2 of of IN cord-022526-j9kg00qf 56 3 fluid fluid NN cord-022526-j9kg00qf 56 4 usually usually RB cord-022526-j9kg00qf 56 5 indicates indicate VBZ cord-022526-j9kg00qf 56 6 ileus ileus NN cord-022526-j9kg00qf 56 7 . . . cord-022526-j9kg00qf 57 1 One one PRP cord-022526-j9kg00qf 57 2 must must MD cord-022526-j9kg00qf 57 3 evaluate evaluate VB cord-022526-j9kg00qf 57 4 the the DT cord-022526-j9kg00qf 57 5 consistency consistency NN cord-022526-j9kg00qf 57 6 of of IN cord-022526-j9kg00qf 57 7 the the DT cord-022526-j9kg00qf 57 8 contents content NNS cord-022526-j9kg00qf 57 9 in in IN cord-022526-j9kg00qf 57 10 light light NN cord-022526-j9kg00qf 57 11 of of IN cord-022526-j9kg00qf 57 12 the the DT cord-022526-j9kg00qf 57 13 size size NN cord-022526-j9kg00qf 57 14 of of IN cord-022526-j9kg00qf 57 15 the the DT cord-022526-j9kg00qf 57 16 segment segment NN cord-022526-j9kg00qf 57 17 ; ; : cord-022526-j9kg00qf 57 18 ingesta ingesta NNP cord-022526-j9kg00qf 57 19 in in IN cord-022526-j9kg00qf 57 20 the the DT cord-022526-j9kg00qf 57 21 ventral ventral JJ cord-022526-j9kg00qf 57 22 colon colon NN cord-022526-j9kg00qf 57 23 of of IN cord-022526-j9kg00qf 57 24 a a DT cord-022526-j9kg00qf 57 25 dehydrated dehydrated JJ cord-022526-j9kg00qf 57 26 patient patient NN cord-022526-j9kg00qf 57 27 may may MD cord-022526-j9kg00qf 57 28 be be VB cord-022526-j9kg00qf 57 29 firm firm JJ cord-022526-j9kg00qf 57 30 , , , cord-022526-j9kg00qf 57 31 but but CC cord-022526-j9kg00qf 57 32 the the DT cord-022526-j9kg00qf 57 33 size size NN cord-022526-j9kg00qf 57 34 of of IN cord-022526-j9kg00qf 57 35 the the DT cord-022526-j9kg00qf 57 36 ventral ventral JJ cord-022526-j9kg00qf 57 37 colon colon NN cord-022526-j9kg00qf 57 38 will will MD cord-022526-j9kg00qf 57 39 be be VB cord-022526-j9kg00qf 57 40 normal normal JJ cord-022526-j9kg00qf 57 41 . . . cord-022526-j9kg00qf 58 1 Conversely conversely RB cord-022526-j9kg00qf 58 2 , , , cord-022526-j9kg00qf 58 3 if if IN cord-022526-j9kg00qf 58 4 the the DT cord-022526-j9kg00qf 58 5 ingesta ingesta NNP cord-022526-j9kg00qf 58 6 is be VBZ cord-022526-j9kg00qf 58 7 firm firm JJ cord-022526-j9kg00qf 58 8 because because IN cord-022526-j9kg00qf 58 9 of of IN cord-022526-j9kg00qf 58 10 a a DT cord-022526-j9kg00qf 58 11 distal distal JJ cord-022526-j9kg00qf 58 12 obstruction obstruction NN cord-022526-j9kg00qf 58 13 , , , cord-022526-j9kg00qf 58 14 the the DT cord-022526-j9kg00qf 58 15 ventral ventral JJ cord-022526-j9kg00qf 58 16 colon colon NN cord-022526-j9kg00qf 58 17 will will MD cord-022526-j9kg00qf 58 18 be be VB cord-022526-j9kg00qf 58 19 enlarged enlarge VBN cord-022526-j9kg00qf 58 20 . . . cord-022526-j9kg00qf 59 1 Displacement displacement NN cord-022526-j9kg00qf 59 2 of of IN cord-022526-j9kg00qf 59 3 a a DT cord-022526-j9kg00qf 59 4 segment segment NN cord-022526-j9kg00qf 59 5 of of IN cord-022526-j9kg00qf 59 6 the the DT cord-022526-j9kg00qf 59 7 large large JJ cord-022526-j9kg00qf 59 8 intestine intestine NN cord-022526-j9kg00qf 59 9 may may MD cord-022526-j9kg00qf 59 10 create create VB cord-022526-j9kg00qf 59 11 an an DT cord-022526-j9kg00qf 59 12 obstruction obstruction NN cord-022526-j9kg00qf 59 13 detectable detectable JJ cord-022526-j9kg00qf 59 14 by by IN cord-022526-j9kg00qf 59 15 enlargement enlargement NN cord-022526-j9kg00qf 59 16 of of IN cord-022526-j9kg00qf 59 17 the the DT cord-022526-j9kg00qf 59 18 segment segment NN cord-022526-j9kg00qf 59 19 and and CC cord-022526-j9kg00qf 59 20 accumulation accumulation NN cord-022526-j9kg00qf 59 21 of of IN cord-022526-j9kg00qf 59 22 gas gas NN cord-022526-j9kg00qf 59 23 and and CC cord-022526-j9kg00qf 59 24 fluid fluid NN cord-022526-j9kg00qf 59 25 , , , cord-022526-j9kg00qf 59 26 even even RB cord-022526-j9kg00qf 59 27 if if IN cord-022526-j9kg00qf 59 28 the the DT cord-022526-j9kg00qf 59 29 site site NN cord-022526-j9kg00qf 59 30 of of IN cord-022526-j9kg00qf 59 31 obstruction obstruction NN cord-022526-j9kg00qf 59 32 is be VBZ cord-022526-j9kg00qf 59 33 not not RB cord-022526-j9kg00qf 59 34 palpable palpable JJ cord-022526-j9kg00qf 59 35 . . . cord-022526-j9kg00qf 60 1 Torsion torsion NN cord-022526-j9kg00qf 60 2 of of IN cord-022526-j9kg00qf 60 3 the the DT cord-022526-j9kg00qf 60 4 ascending ascend VBG cord-022526-j9kg00qf 60 5 colon colon NN cord-022526-j9kg00qf 60 6 at at IN cord-022526-j9kg00qf 60 7 the the DT cord-022526-j9kg00qf 60 8 sternal sternal JJ cord-022526-j9kg00qf 60 9 and and CC cord-022526-j9kg00qf 60 10 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 60 11 flexures flexure NNS cord-022526-j9kg00qf 60 12 results result VBZ cord-022526-j9kg00qf 60 13 in in IN cord-022526-j9kg00qf 60 14 acute acute JJ cord-022526-j9kg00qf 60 15 accumulation accumulation NN cord-022526-j9kg00qf 60 16 of of IN cord-022526-j9kg00qf 60 17 gas gas NN cord-022526-j9kg00qf 60 18 and and CC cord-022526-j9kg00qf 60 19 fluid fluid NN cord-022526-j9kg00qf 60 20 proximal proximal NN cord-022526-j9kg00qf 60 21 to to IN cord-022526-j9kg00qf 60 22 the the DT cord-022526-j9kg00qf 60 23 torsion torsion NN cord-022526-j9kg00qf 60 24 , , , cord-022526-j9kg00qf 60 25 causing cause VBG cord-022526-j9kg00qf 60 26 distention distention NN cord-022526-j9kg00qf 60 27 of of IN cord-022526-j9kg00qf 60 28 the the DT cord-022526-j9kg00qf 60 29 left left JJ cord-022526-j9kg00qf 60 30 dorsal dorsal JJ cord-022526-j9kg00qf 60 31 and and CC cord-022526-j9kg00qf 60 32 ventral ventral JJ cord-022526-j9kg00qf 60 33 colons colon NNS cord-022526-j9kg00qf 60 34 . . . cord-022526-j9kg00qf 61 1 Depending depend VBG cord-022526-j9kg00qf 61 2 on on IN cord-022526-j9kg00qf 61 3 the the DT cord-022526-j9kg00qf 61 4 degree degree NN cord-022526-j9kg00qf 61 5 of of IN cord-022526-j9kg00qf 61 6 torsion torsion NN cord-022526-j9kg00qf 61 7 , , , cord-022526-j9kg00qf 61 8 the the DT cord-022526-j9kg00qf 61 9 position position NN cord-022526-j9kg00qf 61 10 of of IN cord-022526-j9kg00qf 61 11 the the DT cord-022526-j9kg00qf 61 12 ventral ventral JJ cord-022526-j9kg00qf 61 13 and and CC cord-022526-j9kg00qf 61 14 dorsal dorsal JJ cord-022526-j9kg00qf 61 15 colons colon NNS cord-022526-j9kg00qf 61 16 may may MD cord-022526-j9kg00qf 61 17 not not RB cord-022526-j9kg00qf 61 18 be be VB cord-022526-j9kg00qf 61 19 significantly significantly RB cord-022526-j9kg00qf 61 20 abnormal abnormal JJ cord-022526-j9kg00qf 61 21 . . . cord-022526-j9kg00qf 62 1 Displacement displacement NN cord-022526-j9kg00qf 62 2 of of IN cord-022526-j9kg00qf 62 3 a a DT cord-022526-j9kg00qf 62 4 segment segment NN cord-022526-j9kg00qf 62 5 of of IN cord-022526-j9kg00qf 62 6 large large JJ cord-022526-j9kg00qf 62 7 intestine intestine NN cord-022526-j9kg00qf 62 8 often often RB cord-022526-j9kg00qf 62 9 results result VBZ cord-022526-j9kg00qf 62 10 in in IN cord-022526-j9kg00qf 62 11 incomplete incomplete JJ cord-022526-j9kg00qf 62 12 obstruction obstruction NN cord-022526-j9kg00qf 62 13 , , , cord-022526-j9kg00qf 62 14 and and CC cord-022526-j9kg00qf 62 15 the the DT cord-022526-j9kg00qf 62 16 diagnosis diagnosis NN cord-022526-j9kg00qf 62 17 relies rely VBZ cord-022526-j9kg00qf 62 18 solely solely RB cord-022526-j9kg00qf 62 19 on on IN cord-022526-j9kg00qf 62 20 detection detection NN cord-022526-j9kg00qf 62 21 of of IN cord-022526-j9kg00qf 62 22 the the DT cord-022526-j9kg00qf 62 23 displaced displace VBN cord-022526-j9kg00qf 62 24 segment segment NN cord-022526-j9kg00qf 62 25 in in IN cord-022526-j9kg00qf 62 26 an an DT cord-022526-j9kg00qf 62 27 abnormal abnormal JJ cord-022526-j9kg00qf 62 28 position position NN cord-022526-j9kg00qf 62 29 . . . cord-022526-j9kg00qf 63 1 The the DT cord-022526-j9kg00qf 63 2 position position NN cord-022526-j9kg00qf 63 3 of of IN cord-022526-j9kg00qf 63 4 the the DT cord-022526-j9kg00qf 63 5 displaced displace VBN cord-022526-j9kg00qf 63 6 segment segment NN cord-022526-j9kg00qf 63 7 may may MD cord-022526-j9kg00qf 63 8 not not RB cord-022526-j9kg00qf 63 9 be be VB cord-022526-j9kg00qf 63 10 palpable palpable JJ cord-022526-j9kg00qf 63 11 , , , cord-022526-j9kg00qf 63 12 and and CC cord-022526-j9kg00qf 63 13 the the DT cord-022526-j9kg00qf 63 14 diagnosis diagnosis NN cord-022526-j9kg00qf 63 15 then then RB cord-022526-j9kg00qf 63 16 relies rely VBZ cord-022526-j9kg00qf 63 17 on on IN cord-022526-j9kg00qf 63 18 the the DT cord-022526-j9kg00qf 63 19 inability inability NN cord-022526-j9kg00qf 63 20 to to TO cord-022526-j9kg00qf 63 21 find find VB cord-022526-j9kg00qf 63 22 the the DT cord-022526-j9kg00qf 63 23 segment segment NN cord-022526-j9kg00qf 63 24 in in IN cord-022526-j9kg00qf 63 25 a a DT cord-022526-j9kg00qf 63 26 normal normal JJ cord-022526-j9kg00qf 63 27 position position NN cord-022526-j9kg00qf 63 28 . . . cord-022526-j9kg00qf 64 1 One one PRP cord-022526-j9kg00qf 64 2 must must MD cord-022526-j9kg00qf 64 3 take take VB cord-022526-j9kg00qf 64 4 care care NN cord-022526-j9kg00qf 64 5 to to TO cord-022526-j9kg00qf 64 6 ensure ensure VB cord-022526-j9kg00qf 64 7 that that IN cord-022526-j9kg00qf 64 8 the the DT cord-022526-j9kg00qf 64 9 segment segment NN cord-022526-j9kg00qf 64 10 that that WDT cord-022526-j9kg00qf 64 11 appears appear VBZ cord-022526-j9kg00qf 64 12 to to TO cord-022526-j9kg00qf 64 13 be be VB cord-022526-j9kg00qf 64 14 displaced displace VBN cord-022526-j9kg00qf 64 15 is be VBZ cord-022526-j9kg00qf 64 16 not not RB cord-022526-j9kg00qf 64 17 in in IN cord-022526-j9kg00qf 64 18 a a DT cord-022526-j9kg00qf 64 19 normal normal JJ cord-022526-j9kg00qf 64 20 position position NN cord-022526-j9kg00qf 64 21 but but CC cord-022526-j9kg00qf 64 22 has have VBZ cord-022526-j9kg00qf 64 23 become become VBN cord-022526-j9kg00qf 64 24 too too RB cord-022526-j9kg00qf 64 25 small small JJ cord-022526-j9kg00qf 64 26 to to TO cord-022526-j9kg00qf 64 27 palpate palpate VB cord-022526-j9kg00qf 64 28 from from IN cord-022526-j9kg00qf 64 29 a a DT cord-022526-j9kg00qf 64 30 decrease decrease NN cord-022526-j9kg00qf 64 31 in in IN cord-022526-j9kg00qf 64 32 the the DT cord-022526-j9kg00qf 64 33 volume volume NN cord-022526-j9kg00qf 64 34 of of IN cord-022526-j9kg00qf 64 35 ingesta ingesta NNP cord-022526-j9kg00qf 64 36 . . . cord-022526-j9kg00qf 65 1 The the DT cord-022526-j9kg00qf 65 2 cecum cecum NN cord-022526-j9kg00qf 65 3 , , , cord-022526-j9kg00qf 65 4 right right JJ cord-022526-j9kg00qf 65 5 dorsal dorsal JJ cord-022526-j9kg00qf 65 6 and and CC cord-022526-j9kg00qf 65 7 ventral ventral JJ cord-022526-j9kg00qf 65 8 colons colon NNS cord-022526-j9kg00qf 65 9 , , , cord-022526-j9kg00qf 65 10 pelvic pelvic JJ cord-022526-j9kg00qf 65 11 flexure flexure NN cord-022526-j9kg00qf 65 12 , , , cord-022526-j9kg00qf 65 13 and and CC cord-022526-j9kg00qf 65 14 descending descend VBG cord-022526-j9kg00qf 65 15 colon colon NN cord-022526-j9kg00qf 65 16 are be VBP cord-022526-j9kg00qf 65 17 palpable palpable JJ cord-022526-j9kg00qf 65 18 in in IN cord-022526-j9kg00qf 65 19 most most JJS cord-022526-j9kg00qf 65 20 horses horse NNS cord-022526-j9kg00qf 65 21 . . . cord-022526-j9kg00qf 66 1 One one PRP cord-022526-j9kg00qf 66 2 should should MD cord-022526-j9kg00qf 66 3 palpate palpate VB cord-022526-j9kg00qf 66 4 the the DT cord-022526-j9kg00qf 66 5 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 66 6 space space NN cord-022526-j9kg00qf 66 7 to to TO cord-022526-j9kg00qf 66 8 detect detect VB cord-022526-j9kg00qf 66 9 the the DT cord-022526-j9kg00qf 66 10 presence presence NN cord-022526-j9kg00qf 66 11 of of IN cord-022526-j9kg00qf 66 12 intestine intestine NN cord-022526-j9kg00qf 66 13 , , , cord-022526-j9kg00qf 66 14 usually usually RB cord-022526-j9kg00qf 66 15 pelvic pelvic JJ cord-022526-j9kg00qf 66 16 flexure flexure NN cord-022526-j9kg00qf 66 17 , , , cord-022526-j9kg00qf 66 18 entrapped entrap VBN cord-022526-j9kg00qf 66 19 within within IN cord-022526-j9kg00qf 66 20 the the DT cord-022526-j9kg00qf 66 21 ligament ligament NN cord-022526-j9kg00qf 66 22 . . . cord-022526-j9kg00qf 67 1 Small small JJ cord-022526-j9kg00qf 67 2 intestine intestine NN cord-022526-j9kg00qf 67 3 is be VBZ cord-022526-j9kg00qf 67 4 not not RB cord-022526-j9kg00qf 67 5 normally normally RB cord-022526-j9kg00qf 67 6 palpable palpable JJ cord-022526-j9kg00qf 67 7 in in IN cord-022526-j9kg00qf 67 8 the the DT cord-022526-j9kg00qf 67 9 horse horse NN cord-022526-j9kg00qf 67 10 . . . cord-022526-j9kg00qf 68 1 Distention Distention NNP cord-022526-j9kg00qf 68 2 is be VBZ cord-022526-j9kg00qf 68 3 an an DT cord-022526-j9kg00qf 68 4 indicator indicator NN cord-022526-j9kg00qf 68 5 of of IN cord-022526-j9kg00qf 68 6 ileus ileus NN cord-022526-j9kg00qf 68 7 with with IN cord-022526-j9kg00qf 68 8 gas gas NN cord-022526-j9kg00qf 68 9 or or CC cord-022526-j9kg00qf 68 10 fluid fluid JJ cord-022526-j9kg00qf 68 11 retention retention NN cord-022526-j9kg00qf 68 12 , , , cord-022526-j9kg00qf 68 13 usually usually RB cord-022526-j9kg00qf 68 14 following follow VBG cord-022526-j9kg00qf 68 15 a a DT cord-022526-j9kg00qf 68 16 strangulating strangulating JJ cord-022526-j9kg00qf 68 17 or or CC cord-022526-j9kg00qf 68 18 nonstrangulating nonstrangulating JJ cord-022526-j9kg00qf 68 19 obstruction obstruction NN cord-022526-j9kg00qf 68 20 . . . cord-022526-j9kg00qf 69 1 Strangulating strangulating JJ cord-022526-j9kg00qf 69 2 obstructions obstruction NNS cord-022526-j9kg00qf 69 3 result result VBP cord-022526-j9kg00qf 69 4 from from IN cord-022526-j9kg00qf 69 5 conditions condition NNS cord-022526-j9kg00qf 69 6 such such JJ cord-022526-j9kg00qf 69 7 as as IN cord-022526-j9kg00qf 69 8 volvulus volvulus NN cord-022526-j9kg00qf 69 9 or or CC cord-022526-j9kg00qf 69 10 torsion torsion NN cord-022526-j9kg00qf 69 11 , , , cord-022526-j9kg00qf 69 12 lipoma lipoma NN cord-022526-j9kg00qf 69 13 , , , cord-022526-j9kg00qf 69 14 or or CC cord-022526-j9kg00qf 69 15 entrapments entrapment NNS cord-022526-j9kg00qf 69 16 . . . cord-022526-j9kg00qf 70 1 Such such JJ cord-022526-j9kg00qf 70 2 conditions condition NNS cord-022526-j9kg00qf 70 3 often often RB cord-022526-j9kg00qf 70 4 are be VBP cord-022526-j9kg00qf 70 5 accompanied accompany VBN cord-022526-j9kg00qf 70 6 by by IN cord-022526-j9kg00qf 70 7 severe severe JJ cord-022526-j9kg00qf 70 8 pain pain NN cord-022526-j9kg00qf 70 9 , , , cord-022526-j9kg00qf 70 10 dehydration dehydration NN cord-022526-j9kg00qf 70 11 , , , cord-022526-j9kg00qf 70 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 70 13 fluid fluid NN cord-022526-j9kg00qf 70 14 changes change NNS cord-022526-j9kg00qf 70 15 , , , cord-022526-j9kg00qf 70 16 and and CC cord-022526-j9kg00qf 70 17 a a DT cord-022526-j9kg00qf 70 18 varying vary VBG cord-022526-j9kg00qf 70 19 degree degree NN cord-022526-j9kg00qf 70 20 of of IN cord-022526-j9kg00qf 70 21 gastric gastric JJ cord-022526-j9kg00qf 70 22 fluid fluid JJ cord-022526-j9kg00qf 70 23 accumulation accumulation NN cord-022526-j9kg00qf 70 24 . . . cord-022526-j9kg00qf 71 1 The the DT cord-022526-j9kg00qf 71 2 small small JJ cord-022526-j9kg00qf 71 3 intestine intestine NN cord-022526-j9kg00qf 71 4 in in IN cord-022526-j9kg00qf 71 5 these these DT cord-022526-j9kg00qf 71 6 cases case NNS cord-022526-j9kg00qf 71 7 is be VBZ cord-022526-j9kg00qf 71 8 turgid turgid JJ cord-022526-j9kg00qf 71 9 and and CC cord-022526-j9kg00qf 71 10 firm firm JJ cord-022526-j9kg00qf 71 11 on on IN cord-022526-j9kg00qf 71 12 palpation palpation NN cord-022526-j9kg00qf 71 13 . . . cord-022526-j9kg00qf 72 1 One one PRP cord-022526-j9kg00qf 72 2 should should MD cord-022526-j9kg00qf 72 3 assess assess VB cord-022526-j9kg00qf 72 4 the the DT cord-022526-j9kg00qf 72 5 mesentery mesentery NN cord-022526-j9kg00qf 72 6 and and CC cord-022526-j9kg00qf 72 7 wall wall NN cord-022526-j9kg00qf 72 8 thickness thickness NN cord-022526-j9kg00qf 72 9 as as IN cord-022526-j9kg00qf 72 10 for for IN cord-022526-j9kg00qf 72 11 large large JJ cord-022526-j9kg00qf 72 12 intestinal intestinal JJ cord-022526-j9kg00qf 72 13 disorders disorder NNS cord-022526-j9kg00qf 72 14 . . . cord-022526-j9kg00qf 73 1 Careful careful JJ cord-022526-j9kg00qf 73 2 palpation palpation NN cord-022526-j9kg00qf 73 3 of of IN cord-022526-j9kg00qf 73 4 the the DT cord-022526-j9kg00qf 73 5 inguinal inguinal JJ cord-022526-j9kg00qf 73 6 rings ring NNS cord-022526-j9kg00qf 73 7 in in IN cord-022526-j9kg00qf 73 8 stallions stallion NNS cord-022526-j9kg00qf 73 9 with with IN cord-022526-j9kg00qf 73 10 small small JJ cord-022526-j9kg00qf 73 11 intestinal intestinal JJ cord-022526-j9kg00qf 73 12 distention distention NN cord-022526-j9kg00qf 73 13 is be VBZ cord-022526-j9kg00qf 73 14 crucial crucial JJ cord-022526-j9kg00qf 73 15 for for IN cord-022526-j9kg00qf 73 16 determining determine VBG cord-022526-j9kg00qf 73 17 inguinal inguinal JJ cord-022526-j9kg00qf 73 18 herniation herniation NN cord-022526-j9kg00qf 73 19 . . . cord-022526-j9kg00qf 74 1 Evaluation evaluation NN cord-022526-j9kg00qf 74 2 of of IN cord-022526-j9kg00qf 74 3 the the DT cord-022526-j9kg00qf 74 4 wall wall NN cord-022526-j9kg00qf 74 5 thickness thickness NN cord-022526-j9kg00qf 74 6 and and CC cord-022526-j9kg00qf 74 7 mesenteric mesenteric JJ cord-022526-j9kg00qf 74 8 vessels vessel NNS cord-022526-j9kg00qf 74 9 can can MD cord-022526-j9kg00qf 74 10 reveal reveal VB cord-022526-j9kg00qf 74 11 venous venous JJ cord-022526-j9kg00qf 74 12 congestion congestion NN cord-022526-j9kg00qf 74 13 ( ( -LRB- cord-022526-j9kg00qf 74 14 mural mural NN cord-022526-j9kg00qf 74 15 edema edema NN cord-022526-j9kg00qf 74 16 and and CC cord-022526-j9kg00qf 74 17 enlarged enlarged JJ cord-022526-j9kg00qf 74 18 blood blood NN cord-022526-j9kg00qf 74 19 and and CC cord-022526-j9kg00qf 74 20 lymphatic lymphatic JJ cord-022526-j9kg00qf 74 21 vessels vessel NNS cord-022526-j9kg00qf 74 22 ) ) -RRB- cord-022526-j9kg00qf 74 23 or or CC cord-022526-j9kg00qf 74 24 inflammation inflammation NN cord-022526-j9kg00qf 74 25 ( ( -LRB- cord-022526-j9kg00qf 74 26 mural mural NN cord-022526-j9kg00qf 74 27 edema edema NN cord-022526-j9kg00qf 74 28 with with IN cord-022526-j9kg00qf 74 29 normal normal JJ cord-022526-j9kg00qf 74 30 vessels vessel NNS cord-022526-j9kg00qf 74 31 ) ) -RRB- cord-022526-j9kg00qf 74 32 . . . cord-022526-j9kg00qf 75 1 Disruption disruption NN cord-022526-j9kg00qf 75 2 of of IN cord-022526-j9kg00qf 75 3 arterial arterial JJ cord-022526-j9kg00qf 75 4 blood blood NN cord-022526-j9kg00qf 75 5 flow flow NN cord-022526-j9kg00qf 75 6 does do VBZ cord-022526-j9kg00qf 75 7 not not RB cord-022526-j9kg00qf 75 8 cause cause VB cord-022526-j9kg00qf 75 9 venous venous JJ cord-022526-j9kg00qf 75 10 congestion congestion NN cord-022526-j9kg00qf 75 11 , , , cord-022526-j9kg00qf 75 12 but but CC cord-022526-j9kg00qf 75 13 the the DT cord-022526-j9kg00qf 75 14 arterial arterial JJ cord-022526-j9kg00qf 75 15 pulse pulse NN cord-022526-j9kg00qf 75 16 is be VBZ cord-022526-j9kg00qf 75 17 not not RB cord-022526-j9kg00qf 75 18 detectable detectable JJ cord-022526-j9kg00qf 75 19 . . . cord-022526-j9kg00qf 76 1 Mesenteric mesenteric JJ cord-022526-j9kg00qf 76 2 tears tear NNS cord-022526-j9kg00qf 76 3 may may MD cord-022526-j9kg00qf 76 4 not not RB cord-022526-j9kg00qf 76 5 be be VB cord-022526-j9kg00qf 76 6 palpable palpable JJ cord-022526-j9kg00qf 76 7 , , , cord-022526-j9kg00qf 76 8 but but CC cord-022526-j9kg00qf 76 9 the the DT cord-022526-j9kg00qf 76 10 entrapped entrap VBN cord-022526-j9kg00qf 76 11 ischemic ischemic JJ cord-022526-j9kg00qf 76 12 intestinal intestinal JJ cord-022526-j9kg00qf 76 13 segment segment NN cord-022526-j9kg00qf 76 14 may may MD cord-022526-j9kg00qf 76 15 be be VB cord-022526-j9kg00qf 76 16 thickened thicken VBN cord-022526-j9kg00qf 76 17 with with IN cord-022526-j9kg00qf 76 18 edema edema NN cord-022526-j9kg00qf 76 19 . . . cord-022526-j9kg00qf 77 1 One one CD cord-022526-j9kg00qf 77 2 may may MD cord-022526-j9kg00qf 77 3 detect detect VB cord-022526-j9kg00qf 77 4 acute acute JJ cord-022526-j9kg00qf 77 5 or or CC cord-022526-j9kg00qf 77 6 chronic chronic JJ cord-022526-j9kg00qf 77 7 inflammation inflammation NN cord-022526-j9kg00qf 77 8 with with IN cord-022526-j9kg00qf 77 9 cellular cellular JJ cord-022526-j9kg00qf 77 10 infiltration infiltration NN cord-022526-j9kg00qf 77 11 of of IN cord-022526-j9kg00qf 77 12 the the DT cord-022526-j9kg00qf 77 13 intestinal intestinal JJ cord-022526-j9kg00qf 77 14 wall wall NN cord-022526-j9kg00qf 77 15 as as IN cord-022526-j9kg00qf 77 16 thickening thickening NN cord-022526-j9kg00qf 77 17 of of IN cord-022526-j9kg00qf 77 18 the the DT cord-022526-j9kg00qf 77 19 wall wall NN cord-022526-j9kg00qf 77 20 without without IN cord-022526-j9kg00qf 77 21 edema edema NN cord-022526-j9kg00qf 77 22 and and CC cord-022526-j9kg00qf 77 23 also also RB cord-022526-j9kg00qf 77 24 may may MD cord-022526-j9kg00qf 77 25 note note VB cord-022526-j9kg00qf 77 26 enlargement enlargement NN cord-022526-j9kg00qf 77 27 of of IN cord-022526-j9kg00qf 77 28 mesenteric mesenteric JJ cord-022526-j9kg00qf 77 29 lymph lymph NN cord-022526-j9kg00qf 77 30 nodes node NNS cord-022526-j9kg00qf 77 31 . . . cord-022526-j9kg00qf 78 1 One one PRP cord-022526-j9kg00qf 78 2 should should MD cord-022526-j9kg00qf 78 3 interpret interpret VB cord-022526-j9kg00qf 78 4 abnormalities abnormality NNS cord-022526-j9kg00qf 78 5 in in IN cord-022526-j9kg00qf 78 6 the the DT cord-022526-j9kg00qf 78 7 wall wall NN cord-022526-j9kg00qf 78 8 or or CC cord-022526-j9kg00qf 78 9 vessels vessel NNS cord-022526-j9kg00qf 78 10 in in IN cord-022526-j9kg00qf 78 11 light light NN cord-022526-j9kg00qf 78 12 of of IN cord-022526-j9kg00qf 78 13 the the DT cord-022526-j9kg00qf 78 14 size size NN cord-022526-j9kg00qf 78 15 , , , cord-022526-j9kg00qf 78 16 consistency consistency NN cord-022526-j9kg00qf 78 17 , , , cord-022526-j9kg00qf 78 18 and and CC cord-022526-j9kg00qf 78 19 position position NN cord-022526-j9kg00qf 78 20 of of IN cord-022526-j9kg00qf 78 21 the the DT cord-022526-j9kg00qf 78 22 segment segment NN cord-022526-j9kg00qf 78 23 of of IN cord-022526-j9kg00qf 78 24 intestine intestine NN cord-022526-j9kg00qf 78 25 and and CC cord-022526-j9kg00qf 78 26 the the DT cord-022526-j9kg00qf 78 27 clinical clinical JJ cord-022526-j9kg00qf 78 28 signs sign NNS cord-022526-j9kg00qf 78 29 . . . cord-022526-j9kg00qf 79 1 Several several JJ cord-022526-j9kg00qf 79 2 conditions condition NNS cord-022526-j9kg00qf 79 3 involving involve VBG cord-022526-j9kg00qf 79 4 small small JJ cord-022526-j9kg00qf 79 5 intestinal intestinal JJ cord-022526-j9kg00qf 79 6 strangulating strangulating JJ cord-022526-j9kg00qf 79 7 lesions lesion NNS cord-022526-j9kg00qf 79 8 do do VBP cord-022526-j9kg00qf 79 9 not not RB cord-022526-j9kg00qf 79 10 necessarily necessarily RB cord-022526-j9kg00qf 79 11 cause cause VB cord-022526-j9kg00qf 79 12 abnormal abnormal JJ cord-022526-j9kg00qf 79 13 rectal rectal JJ cord-022526-j9kg00qf 79 14 examination examination NN cord-022526-j9kg00qf 79 15 findings finding NNS cord-022526-j9kg00qf 79 16 until until IN cord-022526-j9kg00qf 79 17 the the DT cord-022526-j9kg00qf 79 18 disease disease NN cord-022526-j9kg00qf 79 19 has have VBZ cord-022526-j9kg00qf 79 20 been be VBN cord-022526-j9kg00qf 79 21 present present JJ cord-022526-j9kg00qf 79 22 for for IN cord-022526-j9kg00qf 79 23 an an DT cord-022526-j9kg00qf 79 24 extended extended JJ cord-022526-j9kg00qf 79 25 time time NN cord-022526-j9kg00qf 79 26 . . . cord-022526-j9kg00qf 80 1 These these DT cord-022526-j9kg00qf 80 2 conditions condition NNS cord-022526-j9kg00qf 80 3 include include VBP cord-022526-j9kg00qf 80 4 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 80 5 herniae herniae NN cord-022526-j9kg00qf 80 6 and and CC cord-022526-j9kg00qf 80 7 epiploic epiploic NNP cord-022526-j9kg00qf 80 8 foramen foramen NN cord-022526-j9kg00qf 80 9 entrapments entrapment NNS cord-022526-j9kg00qf 80 10 . . . cord-022526-j9kg00qf 81 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 81 2 fluid fluid JJ cord-022526-j9kg00qf 81 3 analysis analysis NN cord-022526-j9kg00qf 81 4 may may MD cord-022526-j9kg00qf 81 5 be be VB cord-022526-j9kg00qf 81 6 normal normal JJ cord-022526-j9kg00qf 81 7 in in IN cord-022526-j9kg00qf 81 8 these these DT cord-022526-j9kg00qf 81 9 cases case NNS cord-022526-j9kg00qf 81 10 as as RB cord-022526-j9kg00qf 81 11 well well RB cord-022526-j9kg00qf 81 12 because because IN cord-022526-j9kg00qf 81 13 the the DT cord-022526-j9kg00qf 81 14 fluid fluid NN cord-022526-j9kg00qf 81 15 is be VBZ cord-022526-j9kg00qf 81 16 trapped trap VBN cord-022526-j9kg00qf 81 17 in in IN cord-022526-j9kg00qf 81 18 the the DT cord-022526-j9kg00qf 81 19 thorax thorax NN cord-022526-j9kg00qf 81 20 or or CC cord-022526-j9kg00qf 81 21 in in IN cord-022526-j9kg00qf 81 22 the the DT cord-022526-j9kg00qf 81 23 cranial cranial JJ cord-022526-j9kg00qf 81 24 abdomen abdomen NN cord-022526-j9kg00qf 81 25 . . . cord-022526-j9kg00qf 82 1 Surgery surgery NN cord-022526-j9kg00qf 82 2 is be VBZ cord-022526-j9kg00qf 82 3 usually usually RB cord-022526-j9kg00qf 82 4 necessary necessary JJ cord-022526-j9kg00qf 82 5 for for IN cord-022526-j9kg00qf 82 6 diagnosis diagnosis NN cord-022526-j9kg00qf 82 7 . . . cord-022526-j9kg00qf 83 1 Nonstrangulating nonstrangulating NN cord-022526-j9kg00qf 83 2 causes cause NNS cord-022526-j9kg00qf 83 3 of of IN cord-022526-j9kg00qf 83 4 small small JJ cord-022526-j9kg00qf 83 5 intestinal intestinal JJ cord-022526-j9kg00qf 83 6 distention distention NN cord-022526-j9kg00qf 83 7 can can MD cord-022526-j9kg00qf 83 8 be be VB cord-022526-j9kg00qf 83 9 divided divide VBN cord-022526-j9kg00qf 83 10 further further RB cord-022526-j9kg00qf 83 11 into into IN cord-022526-j9kg00qf 83 12 intraluminal intraluminal JJ cord-022526-j9kg00qf 83 13 and and CC cord-022526-j9kg00qf 83 14 extraluminal extraluminal JJ cord-022526-j9kg00qf 83 15 obstructions obstruction NNS cord-022526-j9kg00qf 83 16 . . . cord-022526-j9kg00qf 84 1 Ileal ileal NN cord-022526-j9kg00qf 84 2 impactions impaction NNS cord-022526-j9kg00qf 84 3 are be VBP cord-022526-j9kg00qf 84 4 probably probably RB cord-022526-j9kg00qf 84 5 the the DT cord-022526-j9kg00qf 84 6 most most RBS cord-022526-j9kg00qf 84 7 common common JJ cord-022526-j9kg00qf 84 8 cause cause NN cord-022526-j9kg00qf 84 9 of of IN cord-022526-j9kg00qf 84 10 intraluminal intraluminal JJ cord-022526-j9kg00qf 84 11 obstructions obstruction NNS cord-022526-j9kg00qf 84 12 , , , cord-022526-j9kg00qf 84 13 and and CC cord-022526-j9kg00qf 84 14 on on IN cord-022526-j9kg00qf 84 15 rare rare JJ cord-022526-j9kg00qf 84 16 occasions occasion NNS cord-022526-j9kg00qf 84 17 one one PRP cord-022526-j9kg00qf 84 18 can can MD cord-022526-j9kg00qf 84 19 palpate palpate VB cord-022526-j9kg00qf 84 20 the the DT cord-022526-j9kg00qf 84 21 impaction impaction NN cord-022526-j9kg00qf 84 22 in in IN cord-022526-j9kg00qf 84 23 the the DT cord-022526-j9kg00qf 84 24 upper upper JJ cord-022526-j9kg00qf 84 25 right right JJ cord-022526-j9kg00qf 84 26 quadrant quadrant NN cord-022526-j9kg00qf 84 27 , , , cord-022526-j9kg00qf 84 28 near near IN cord-022526-j9kg00qf 84 29 the the DT cord-022526-j9kg00qf 84 30 ileocecal ileocecal JJ cord-022526-j9kg00qf 84 31 opening opening NN cord-022526-j9kg00qf 84 32 . . . cord-022526-j9kg00qf 85 1 Intraluminal intraluminal JJ cord-022526-j9kg00qf 85 2 masses masse NNS cord-022526-j9kg00qf 85 3 caused cause VBN cord-022526-j9kg00qf 85 4 by by IN cord-022526-j9kg00qf 85 5 lymphoma lymphoma NN cord-022526-j9kg00qf 85 6 , , , cord-022526-j9kg00qf 85 7 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 85 8 enteritis enteritis NN cord-022526-j9kg00qf 85 9 , , , cord-022526-j9kg00qf 85 10 foreign foreign JJ cord-022526-j9kg00qf 85 11 bodies body NNS cord-022526-j9kg00qf 85 12 or or CC cord-022526-j9kg00qf 85 13 ascarid ascarid NN cord-022526-j9kg00qf 85 14 impactions impaction NNS cord-022526-j9kg00qf 85 15 often often RB cord-022526-j9kg00qf 85 16 lead lead VBP cord-022526-j9kg00qf 85 17 to to IN cord-022526-j9kg00qf 85 18 small small JJ cord-022526-j9kg00qf 85 19 intestinal intestinal JJ cord-022526-j9kg00qf 85 20 distention distention NN cord-022526-j9kg00qf 85 21 and and CC cord-022526-j9kg00qf 85 22 are be VBP cord-022526-j9kg00qf 85 23 usually usually RB cord-022526-j9kg00qf 85 24 indistinguishable indistinguishable JJ cord-022526-j9kg00qf 85 25 from from IN cord-022526-j9kg00qf 85 26 one one CD cord-022526-j9kg00qf 85 27 another another DT cord-022526-j9kg00qf 85 28 based base VBN cord-022526-j9kg00qf 85 29 on on IN cord-022526-j9kg00qf 85 30 palpation palpation NN cord-022526-j9kg00qf 85 31 alone alone RB cord-022526-j9kg00qf 85 32 . . . cord-022526-j9kg00qf 86 1 Small small JJ cord-022526-j9kg00qf 86 2 intestine intestine NN cord-022526-j9kg00qf 86 3 in in IN cord-022526-j9kg00qf 86 4 these these DT cord-022526-j9kg00qf 86 5 cases case NNS cord-022526-j9kg00qf 86 6 can can MD cord-022526-j9kg00qf 86 7 be be VB cord-022526-j9kg00qf 86 8 moderately moderately RB cord-022526-j9kg00qf 86 9 to to IN cord-022526-j9kg00qf 86 10 severely severely RB cord-022526-j9kg00qf 86 11 distended distend VBN cord-022526-j9kg00qf 86 12 , , , cord-022526-j9kg00qf 86 13 depending depend VBG cord-022526-j9kg00qf 86 14 on on IN cord-022526-j9kg00qf 86 15 the the DT cord-022526-j9kg00qf 86 16 degree degree NN cord-022526-j9kg00qf 86 17 of of IN cord-022526-j9kg00qf 86 18 obstruction obstruction NN cord-022526-j9kg00qf 86 19 . . . cord-022526-j9kg00qf 87 1 Extraluminal extraluminal JJ cord-022526-j9kg00qf 87 2 obstructions obstruction NNS cord-022526-j9kg00qf 87 3 include include VBP cord-022526-j9kg00qf 87 4 abdominal abdominal JJ cord-022526-j9kg00qf 87 5 masses masse NNS cord-022526-j9kg00qf 87 6 , , , cord-022526-j9kg00qf 87 7 abscesses abscess NNS cord-022526-j9kg00qf 87 8 or or CC cord-022526-j9kg00qf 87 9 tumors tumor NNS cord-022526-j9kg00qf 87 10 , , , cord-022526-j9kg00qf 87 11 and and CC cord-022526-j9kg00qf 87 12 large large JJ cord-022526-j9kg00qf 87 13 colon colon NN cord-022526-j9kg00qf 87 14 displacement displacement NN cord-022526-j9kg00qf 87 15 . . . cord-022526-j9kg00qf 88 1 One one CD cord-022526-j9kg00qf 88 2 always always RB cord-022526-j9kg00qf 88 3 should should MD cord-022526-j9kg00qf 88 4 palpate palpate VB cord-022526-j9kg00qf 88 5 the the DT cord-022526-j9kg00qf 88 6 rest rest NN cord-022526-j9kg00qf 88 7 of of IN cord-022526-j9kg00qf 88 8 the the DT cord-022526-j9kg00qf 88 9 abdomen abdoman NNS cord-022526-j9kg00qf 88 10 carefully carefully RB cord-022526-j9kg00qf 88 11 to to TO cord-022526-j9kg00qf 88 12 help help VB cord-022526-j9kg00qf 88 13 rule rule VB cord-022526-j9kg00qf 88 14 out out RP cord-022526-j9kg00qf 88 15 these these DT cord-022526-j9kg00qf 88 16 causes cause NNS cord-022526-j9kg00qf 88 17 . . . cord-022526-j9kg00qf 89 1 Some some DT cord-022526-j9kg00qf 89 2 cases case NNS cord-022526-j9kg00qf 89 3 of of IN cord-022526-j9kg00qf 89 4 small small JJ cord-022526-j9kg00qf 89 5 intestinal intestinal JJ cord-022526-j9kg00qf 89 6 distention distention NN cord-022526-j9kg00qf 89 7 result result NN cord-022526-j9kg00qf 89 8 from from IN cord-022526-j9kg00qf 89 9 a a DT cord-022526-j9kg00qf 89 10 physiologic physiologic JJ cord-022526-j9kg00qf 89 11 rather rather RB cord-022526-j9kg00qf 89 12 than than IN cord-022526-j9kg00qf 89 13 a a DT cord-022526-j9kg00qf 89 14 mechanical mechanical JJ cord-022526-j9kg00qf 89 15 obstruction obstruction NN cord-022526-j9kg00qf 89 16 . . . cord-022526-j9kg00qf 90 1 Ileus Ileus NNP cord-022526-j9kg00qf 90 2 may may MD cord-022526-j9kg00qf 90 3 result result VB cord-022526-j9kg00qf 90 4 postoperatively postoperatively RB cord-022526-j9kg00qf 90 5 or or CC cord-022526-j9kg00qf 90 6 following follow VBG cord-022526-j9kg00qf 90 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 90 8 diseases disease NNS cord-022526-j9kg00qf 90 9 of of IN cord-022526-j9kg00qf 90 10 the the DT cord-022526-j9kg00qf 90 11 bowel bowel NN cord-022526-j9kg00qf 90 12 ( ( -LRB- cord-022526-j9kg00qf 90 13 proximal proximal JJ cord-022526-j9kg00qf 90 14 enteritis enteritis NN cord-022526-j9kg00qf 90 15 ) ) -RRB- cord-022526-j9kg00qf 90 16 or or CC cord-022526-j9kg00qf 90 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 90 18 cavity cavity NN cord-022526-j9kg00qf 90 19 ( ( -LRB- cord-022526-j9kg00qf 90 20 peritonitis peritonitis NN cord-022526-j9kg00qf 90 21 ) ) -RRB- cord-022526-j9kg00qf 90 22 . . . cord-022526-j9kg00qf 91 1 The the DT cord-022526-j9kg00qf 91 2 bowel bowel NN cord-022526-j9kg00qf 91 3 is be VBZ cord-022526-j9kg00qf 91 4 usually usually RB cord-022526-j9kg00qf 91 5 mildly mildly RB cord-022526-j9kg00qf 91 6 to to TO cord-022526-j9kg00qf 91 7 moderately moderately RB cord-022526-j9kg00qf 91 8 distended distended JJ cord-022526-j9kg00qf 91 9 and and CC cord-022526-j9kg00qf 91 10 almost almost RB cord-022526-j9kg00qf 91 11 always always RB cord-022526-j9kg00qf 91 12 is be VBZ cord-022526-j9kg00qf 91 13 accompanied accompany VBN cord-022526-j9kg00qf 91 14 by by IN cord-022526-j9kg00qf 91 15 significant significant JJ cord-022526-j9kg00qf 91 16 amounts amount NNS cord-022526-j9kg00qf 91 17 of of IN cord-022526-j9kg00qf 91 18 accumulated accumulate VBN cord-022526-j9kg00qf 91 19 gastric gastric JJ cord-022526-j9kg00qf 91 20 fluid fluid NN cord-022526-j9kg00qf 91 21 . . . cord-022526-j9kg00qf 92 1 The the DT cord-022526-j9kg00qf 92 2 small small JJ cord-022526-j9kg00qf 92 3 colon colon NN cord-022526-j9kg00qf 92 4 is be VBZ cord-022526-j9kg00qf 92 5 easily easily RB cord-022526-j9kg00qf 92 6 distinguishable distinguishable JJ cord-022526-j9kg00qf 92 7 by by IN cord-022526-j9kg00qf 92 8 the the DT cord-022526-j9kg00qf 92 9 presence presence NN cord-022526-j9kg00qf 92 10 of of IN cord-022526-j9kg00qf 92 11 normal normal JJ cord-022526-j9kg00qf 92 12 fecal fecal JJ cord-022526-j9kg00qf 92 13 balls ball NNS cord-022526-j9kg00qf 92 14 and and CC cord-022526-j9kg00qf 92 15 an an DT cord-022526-j9kg00qf 92 16 antimesenteric antimesenteric JJ cord-022526-j9kg00qf 92 17 band band NN cord-022526-j9kg00qf 92 18 . . . cord-022526-j9kg00qf 93 1 In in IN cord-022526-j9kg00qf 93 2 cases case NNS cord-022526-j9kg00qf 93 3 of of IN cord-022526-j9kg00qf 93 4 impaction impaction NN cord-022526-j9kg00qf 93 5 of of IN cord-022526-j9kg00qf 93 6 the the DT cord-022526-j9kg00qf 93 7 small small JJ cord-022526-j9kg00qf 93 8 colon colon NN cord-022526-j9kg00qf 93 9 , , , cord-022526-j9kg00qf 93 10 a a DT cord-022526-j9kg00qf 93 11 long long JJ cord-022526-j9kg00qf 93 12 , , , cord-022526-j9kg00qf 93 13 hard hard JJ cord-022526-j9kg00qf 93 14 , , , cord-022526-j9kg00qf 93 15 tubelike tubelike NN cord-022526-j9kg00qf 93 16 structure structure NN cord-022526-j9kg00qf 93 17 is be VBZ cord-022526-j9kg00qf 93 18 present present JJ cord-022526-j9kg00qf 93 19 in in IN cord-022526-j9kg00qf 93 20 the the DT cord-022526-j9kg00qf 93 21 caudal caudal JJ cord-022526-j9kg00qf 93 22 abdomen abdomen NN cord-022526-j9kg00qf 93 23 , , , cord-022526-j9kg00qf 93 24 and and CC cord-022526-j9kg00qf 93 25 the the DT cord-022526-j9kg00qf 93 26 band band NN cord-022526-j9kg00qf 93 27 is be VBZ cord-022526-j9kg00qf 93 28 palpable palpable JJ cord-022526-j9kg00qf 93 29 along along IN cord-022526-j9kg00qf 93 30 the the DT cord-022526-j9kg00qf 93 31 length length NN cord-022526-j9kg00qf 93 32 . . . cord-022526-j9kg00qf 94 1 Fluid fluid JJ cord-022526-j9kg00qf 94 2 stool stool NN cord-022526-j9kg00qf 94 3 is be VBZ cord-022526-j9kg00qf 94 4 often often RB cord-022526-j9kg00qf 94 5 present present JJ cord-022526-j9kg00qf 94 6 in in IN cord-022526-j9kg00qf 94 7 the the DT cord-022526-j9kg00qf 94 8 rectum rectum NN cord-022526-j9kg00qf 94 9 in in IN cord-022526-j9kg00qf 94 10 these these DT cord-022526-j9kg00qf 94 11 cases case NNS cord-022526-j9kg00qf 94 12 , , , cord-022526-j9kg00qf 94 13 as as IN cord-022526-j9kg00qf 94 14 is be VBZ cord-022526-j9kg00qf 94 15 tenesmus tenesmus NNP cord-022526-j9kg00qf 94 16 . . . cord-022526-j9kg00qf 95 1 One one PRP cord-022526-j9kg00qf 95 2 can can MD cord-022526-j9kg00qf 95 3 detect detect VB cord-022526-j9kg00qf 95 4 and and CC cord-022526-j9kg00qf 95 5 carefully carefully RB cord-022526-j9kg00qf 95 6 evaluate evaluate VB cord-022526-j9kg00qf 95 7 rectal rectal JJ cord-022526-j9kg00qf 95 8 tears tear NNS cord-022526-j9kg00qf 95 9 by by IN cord-022526-j9kg00qf 95 10 palpation palpation NN cord-022526-j9kg00qf 95 11 . . . cord-022526-j9kg00qf 96 1 One one PRP cord-022526-j9kg00qf 96 2 can can MD cord-022526-j9kg00qf 96 3 detect detect VB cord-022526-j9kg00qf 96 4 mural mural NN cord-022526-j9kg00qf 96 5 masses masse NNS cord-022526-j9kg00qf 96 6 in in IN cord-022526-j9kg00qf 96 7 palpable palpable JJ cord-022526-j9kg00qf 96 8 segments segment NNS cord-022526-j9kg00qf 96 9 of of IN cord-022526-j9kg00qf 96 10 intestine intestine NN cord-022526-j9kg00qf 96 11 or or CC cord-022526-j9kg00qf 96 12 mesentery mesentery NN cord-022526-j9kg00qf 96 13 ; ; : cord-022526-j9kg00qf 96 14 however however RB cord-022526-j9kg00qf 96 15 , , , cord-022526-j9kg00qf 96 16 if if IN cord-022526-j9kg00qf 96 17 a a DT cord-022526-j9kg00qf 96 18 mass mass NN cord-022526-j9kg00qf 96 19 causes cause VBZ cord-022526-j9kg00qf 96 20 obstruction obstruction NN cord-022526-j9kg00qf 96 21 , , , cord-022526-j9kg00qf 96 22 one one PRP cord-022526-j9kg00qf 96 23 can can MD cord-022526-j9kg00qf 96 24 detect detect VB cord-022526-j9kg00qf 96 25 the the DT cord-022526-j9kg00qf 96 26 result result NN cord-022526-j9kg00qf 96 27 of of IN cord-022526-j9kg00qf 96 28 the the DT cord-022526-j9kg00qf 96 29 obstruction obstruction NN cord-022526-j9kg00qf 96 30 in in IN cord-022526-j9kg00qf 96 31 proximal proximal JJ cord-022526-j9kg00qf 96 32 segments segment NNS cord-022526-j9kg00qf 96 33 of of IN cord-022526-j9kg00qf 96 34 intestine intestine NN cord-022526-j9kg00qf 96 35 even even RB cord-022526-j9kg00qf 96 36 if if IN cord-022526-j9kg00qf 96 37 the the DT cord-022526-j9kg00qf 96 38 mass mass NN cord-022526-j9kg00qf 96 39 is be VBZ cord-022526-j9kg00qf 96 40 unreachable unreachable JJ cord-022526-j9kg00qf 96 41 . . . cord-022526-j9kg00qf 97 1 Palpation palpation NN cord-022526-j9kg00qf 97 2 of of IN cord-022526-j9kg00qf 97 3 the the DT cord-022526-j9kg00qf 97 4 mesenteric mesenteric JJ cord-022526-j9kg00qf 97 5 vessels vessel NNS cord-022526-j9kg00qf 97 6 may may MD cord-022526-j9kg00qf 97 7 reveal reveal VB cord-022526-j9kg00qf 97 8 thickening thickening NN cord-022526-j9kg00qf 97 9 and and CC cord-022526-j9kg00qf 97 10 thrombosis thrombosis NN cord-022526-j9kg00qf 97 11 , , , cord-022526-j9kg00qf 97 12 which which WDT cord-022526-j9kg00qf 97 13 can can MD cord-022526-j9kg00qf 97 14 lead lead VB cord-022526-j9kg00qf 97 15 to to IN cord-022526-j9kg00qf 97 16 ischemia ischemia NN cord-022526-j9kg00qf 97 17 or or CC cord-022526-j9kg00qf 97 18 infarction infarction NN cord-022526-j9kg00qf 97 19 . . . cord-022526-j9kg00qf 98 1 One one PRP cord-022526-j9kg00qf 98 2 can can MD cord-022526-j9kg00qf 98 3 perform perform VB cord-022526-j9kg00qf 98 4 visual visual JJ cord-022526-j9kg00qf 98 5 inspection inspection NN cord-022526-j9kg00qf 98 6 of of IN cord-022526-j9kg00qf 98 7 the the DT cord-022526-j9kg00qf 98 8 mucosa mucosa NN cord-022526-j9kg00qf 98 9 of of IN cord-022526-j9kg00qf 98 10 the the DT cord-022526-j9kg00qf 98 11 rectum rectum NN cord-022526-j9kg00qf 98 12 and and CC cord-022526-j9kg00qf 98 13 descending descend VBG cord-022526-j9kg00qf 98 14 colon colon NN cord-022526-j9kg00qf 98 15 with with IN cord-022526-j9kg00qf 98 16 a a DT cord-022526-j9kg00qf 98 17 speculum speculum NN cord-022526-j9kg00qf 98 18 or or CC cord-022526-j9kg00qf 98 19 flexible flexible JJ cord-022526-j9kg00qf 98 20 endoscope endoscope NN cord-022526-j9kg00qf 98 21 and and CC cord-022526-j9kg00qf 98 22 also also RB cord-022526-j9kg00qf 98 23 can can MD cord-022526-j9kg00qf 98 24 evaluate evaluate VB cord-022526-j9kg00qf 98 25 rectal rectal JJ cord-022526-j9kg00qf 98 26 tears tear NNS cord-022526-j9kg00qf 98 27 or or CC cord-022526-j9kg00qf 98 28 perforations perforation NNS cord-022526-j9kg00qf 98 29 , , , cord-022526-j9kg00qf 98 30 mural mural NN cord-022526-j9kg00qf 98 31 masses masse NNS cord-022526-j9kg00qf 98 32 , , , cord-022526-j9kg00qf 98 33 strictures stricture NNS cord-022526-j9kg00qf 98 34 , , , cord-022526-j9kg00qf 98 35 or or CC cord-022526-j9kg00qf 98 36 mucosal mucosal JJ cord-022526-j9kg00qf 98 37 inflammation inflammation NN cord-022526-j9kg00qf 98 38 . . . cord-022526-j9kg00qf 99 1 One one CD cord-022526-j9kg00qf 99 2 also also RB cord-022526-j9kg00qf 99 3 can can MD cord-022526-j9kg00qf 99 4 perform perform VB cord-022526-j9kg00qf 99 5 guided guide VBN cord-022526-j9kg00qf 99 6 biopsy biopsy NN cord-022526-j9kg00qf 99 7 of of IN cord-022526-j9kg00qf 99 8 the the DT cord-022526-j9kg00qf 99 9 mucosa mucosa JJ cord-022526-j9kg00qf 99 10 or or CC cord-022526-j9kg00qf 99 11 masses masse NNS cord-022526-j9kg00qf 99 12 . . . cord-022526-j9kg00qf 100 1 The the DT cord-022526-j9kg00qf 100 2 obvious obvious JJ cord-022526-j9kg00qf 100 3 limitations limitation NNS cord-022526-j9kg00qf 100 4 are be VBP cord-022526-j9kg00qf 100 5 the the DT cord-022526-j9kg00qf 100 6 amount amount NN cord-022526-j9kg00qf 100 7 of of IN cord-022526-j9kg00qf 100 8 fecal fecal JJ cord-022526-j9kg00qf 100 9 material material NN cord-022526-j9kg00qf 100 10 interfering interfere VBG cord-022526-j9kg00qf 100 11 with with IN cord-022526-j9kg00qf 100 12 the the DT cord-022526-j9kg00qf 100 13 examination examination NN cord-022526-j9kg00qf 100 14 and and CC cord-022526-j9kg00qf 100 15 the the DT cord-022526-j9kg00qf 100 16 distance distance NN cord-022526-j9kg00qf 100 17 of of IN cord-022526-j9kg00qf 100 18 the the DT cord-022526-j9kg00qf 100 19 lesion lesion NN cord-022526-j9kg00qf 100 20 of of IN cord-022526-j9kg00qf 100 21 interest interest NN cord-022526-j9kg00qf 100 22 from from IN cord-022526-j9kg00qf 100 23 the the DT cord-022526-j9kg00qf 100 24 anus anus NN cord-022526-j9kg00qf 100 25 . . . cord-022526-j9kg00qf 101 1 These these DT cord-022526-j9kg00qf 101 2 techniques technique NNS cord-022526-j9kg00qf 101 3 offer offer VBP cord-022526-j9kg00qf 101 4 little little JJ cord-022526-j9kg00qf 101 5 advantage advantage NN cord-022526-j9kg00qf 101 6 over over IN cord-022526-j9kg00qf 101 7 palpation palpation NN cord-022526-j9kg00qf 101 8 in in IN cord-022526-j9kg00qf 101 9 many many JJ cord-022526-j9kg00qf 101 10 cases case NNS cord-022526-j9kg00qf 101 11 unless unless IN cord-022526-j9kg00qf 101 12 the the DT cord-022526-j9kg00qf 101 13 patient patient NN cord-022526-j9kg00qf 101 14 is be VBZ cord-022526-j9kg00qf 101 15 too too RB cord-022526-j9kg00qf 101 16 small small JJ cord-022526-j9kg00qf 101 17 to to TO cord-022526-j9kg00qf 101 18 palpate palpate VB cord-022526-j9kg00qf 101 19 . . . cord-022526-j9kg00qf 102 1 Examination examination NN cord-022526-j9kg00qf 102 2 of of IN cord-022526-j9kg00qf 102 3 the the DT cord-022526-j9kg00qf 102 4 oral oral JJ cord-022526-j9kg00qf 102 5 cavity cavity NN cord-022526-j9kg00qf 102 6 in in IN cord-022526-j9kg00qf 102 7 cases case NNS cord-022526-j9kg00qf 102 8 of of IN cord-022526-j9kg00qf 102 9 dysphagia dysphagia NN cord-022526-j9kg00qf 102 10 or or CC cord-022526-j9kg00qf 102 11 weight weight NN cord-022526-j9kg00qf 102 12 loss loss NN cord-022526-j9kg00qf 102 13 is be VBZ cord-022526-j9kg00qf 102 14 a a DT cord-022526-j9kg00qf 102 15 necessary necessary JJ cord-022526-j9kg00qf 102 16 part part NN cord-022526-j9kg00qf 102 17 of of IN cord-022526-j9kg00qf 102 18 the the DT cord-022526-j9kg00qf 102 19 physical physical JJ cord-022526-j9kg00qf 102 20 examination examination NN cord-022526-j9kg00qf 102 21 . . . cord-022526-j9kg00qf 103 1 One one PRP cord-022526-j9kg00qf 103 2 should should MD cord-022526-j9kg00qf 103 3 adequately adequately RB cord-022526-j9kg00qf 103 4 sedate sedate VB cord-022526-j9kg00qf 103 5 the the DT cord-022526-j9kg00qf 103 6 horse horse NN cord-022526-j9kg00qf 103 7 and and CC cord-022526-j9kg00qf 103 8 should should MD cord-022526-j9kg00qf 103 9 use use VB cord-022526-j9kg00qf 103 10 a a DT cord-022526-j9kg00qf 103 11 full full JJ cord-022526-j9kg00qf 103 12 - - HYPH cord-022526-j9kg00qf 103 13 mouth mouth NN cord-022526-j9kg00qf 103 14 speculum speculum NN cord-022526-j9kg00qf 103 15 to to TO cord-022526-j9kg00qf 103 16 allow allow VB cord-022526-j9kg00qf 103 17 palpation palpation NN cord-022526-j9kg00qf 103 18 and and CC cord-022526-j9kg00qf 103 19 visualization visualization NN cord-022526-j9kg00qf 103 20 of of IN cord-022526-j9kg00qf 103 21 all all DT cord-022526-j9kg00qf 103 22 parts part NNS cord-022526-j9kg00qf 103 23 of of IN cord-022526-j9kg00qf 103 24 the the DT cord-022526-j9kg00qf 103 25 oral oral JJ cord-022526-j9kg00qf 103 26 cavity cavity NN cord-022526-j9kg00qf 103 27 . . . cord-022526-j9kg00qf 104 1 One one PRP cord-022526-j9kg00qf 104 2 should should MD cord-022526-j9kg00qf 104 3 examine examine VB cord-022526-j9kg00qf 104 4 the the DT cord-022526-j9kg00qf 104 5 area area NN cord-022526-j9kg00qf 104 6 for for IN cord-022526-j9kg00qf 104 7 abnormal abnormal JJ cord-022526-j9kg00qf 104 8 dentition dentition NN cord-022526-j9kg00qf 104 9 , , , cord-022526-j9kg00qf 104 10 foreign foreign JJ cord-022526-j9kg00qf 104 11 bodies body NNS cord-022526-j9kg00qf 104 12 , , , cord-022526-j9kg00qf 104 13 fractures fracture NNS cord-022526-j9kg00qf 104 14 , , , cord-022526-j9kg00qf 104 15 abscesses abscess NNS cord-022526-j9kg00qf 104 16 , , , cord-022526-j9kg00qf 104 17 and and CC cord-022526-j9kg00qf 104 18 ulceration ulceration NN cord-022526-j9kg00qf 104 19 . . . cord-022526-j9kg00qf 105 1 The the DT cord-022526-j9kg00qf 105 2 presence presence NN cord-022526-j9kg00qf 105 3 of of IN cord-022526-j9kg00qf 105 4 fluid fluid JJ cord-022526-j9kg00qf 105 5 accumulation accumulation NN cord-022526-j9kg00qf 105 6 in in IN cord-022526-j9kg00qf 105 7 the the DT cord-022526-j9kg00qf 105 8 stomach stomach NN cord-022526-j9kg00qf 105 9 indicates indicate VBZ cord-022526-j9kg00qf 105 10 a a DT cord-022526-j9kg00qf 105 11 decrease decrease NN cord-022526-j9kg00qf 105 12 or or CC cord-022526-j9kg00qf 105 13 absence absence NN cord-022526-j9kg00qf 105 14 in in IN cord-022526-j9kg00qf 105 15 propulsive propulsive JJ cord-022526-j9kg00qf 105 16 motions motion NNS cord-022526-j9kg00qf 105 17 of of IN cord-022526-j9kg00qf 105 18 the the DT cord-022526-j9kg00qf 105 19 small small JJ cord-022526-j9kg00qf 105 20 intestine intestine NN cord-022526-j9kg00qf 105 21 or or CC cord-022526-j9kg00qf 105 22 obstruction obstruction NN cord-022526-j9kg00qf 105 23 of of IN cord-022526-j9kg00qf 105 24 gastric gastric JJ cord-022526-j9kg00qf 105 25 outflow outflow NN cord-022526-j9kg00qf 105 26 . . . cord-022526-j9kg00qf 106 1 Decreased decrease VBD cord-022526-j9kg00qf 106 2 small small JJ cord-022526-j9kg00qf 106 3 intestinal intestinal JJ cord-022526-j9kg00qf 106 4 motility motility NN cord-022526-j9kg00qf 106 5 may may MD cord-022526-j9kg00qf 106 6 result result VB cord-022526-j9kg00qf 106 7 from from IN cord-022526-j9kg00qf 106 8 a a DT cord-022526-j9kg00qf 106 9 functional functional JJ cord-022526-j9kg00qf 106 10 or or CC cord-022526-j9kg00qf 106 11 mechanical mechanical JJ cord-022526-j9kg00qf 106 12 blockage blockage NN cord-022526-j9kg00qf 106 13 . . . cord-022526-j9kg00qf 107 1 Masses masse NNS cord-022526-j9kg00qf 107 2 , , , cord-022526-j9kg00qf 107 3 feed feed NN cord-022526-j9kg00qf 107 4 impactions impaction NNS cord-022526-j9kg00qf 107 5 , , , cord-022526-j9kg00qf 107 6 or or CC cord-022526-j9kg00qf 107 7 strictures stricture NNS cord-022526-j9kg00qf 107 8 in in IN cord-022526-j9kg00qf 107 9 the the DT cord-022526-j9kg00qf 107 10 pylorus pylorus NN cord-022526-j9kg00qf 107 11 or or CC cord-022526-j9kg00qf 107 12 in in IN cord-022526-j9kg00qf 107 13 the the DT cord-022526-j9kg00qf 107 14 proximal proximal JJ cord-022526-j9kg00qf 107 15 duodenum duodenum NN cord-022526-j9kg00qf 107 16 may may MD cord-022526-j9kg00qf 107 17 obstruct obstruct VB cord-022526-j9kg00qf 107 18 gastric gastric JJ cord-022526-j9kg00qf 107 19 outflow outflow NN cord-022526-j9kg00qf 107 20 . . . cord-022526-j9kg00qf 108 1 One one PRP cord-022526-j9kg00qf 108 2 routinely routinely RB cord-022526-j9kg00qf 108 3 assesses assess VBZ cord-022526-j9kg00qf 108 4 fluid fluid JJ cord-022526-j9kg00qf 108 5 accumulation accumulation NN cord-022526-j9kg00qf 108 6 in in IN cord-022526-j9kg00qf 108 7 the the DT cord-022526-j9kg00qf 108 8 stomach stomach NN cord-022526-j9kg00qf 108 9 by by IN cord-022526-j9kg00qf 108 10 siphoning siphon VBG cord-022526-j9kg00qf 108 11 off off RP cord-022526-j9kg00qf 108 12 the the DT cord-022526-j9kg00qf 108 13 gastric gastric JJ cord-022526-j9kg00qf 108 14 contents content NNS cord-022526-j9kg00qf 108 15 with with IN cord-022526-j9kg00qf 108 16 a a DT cord-022526-j9kg00qf 108 17 nasogastric nasogastric NN cord-022526-j9kg00qf 108 18 tube tube NN cord-022526-j9kg00qf 108 19 and and CC cord-022526-j9kg00qf 108 20 examining examine VBG cord-022526-j9kg00qf 108 21 the the DT cord-022526-j9kg00qf 108 22 fluid fluid NN cord-022526-j9kg00qf 108 23 for for IN cord-022526-j9kg00qf 108 24 amount amount NN cord-022526-j9kg00qf 108 25 , , , cord-022526-j9kg00qf 108 26 color color NN cord-022526-j9kg00qf 108 27 , , , cord-022526-j9kg00qf 108 28 and and CC cord-022526-j9kg00qf 108 29 any any DT cord-022526-j9kg00qf 108 30 particular particular JJ cord-022526-j9kg00qf 108 31 odor odor NN cord-022526-j9kg00qf 108 32 . . . cord-022526-j9kg00qf 109 1 Normal normal JJ cord-022526-j9kg00qf 109 2 fluid fluid NN cord-022526-j9kg00qf 109 3 is be VBZ cord-022526-j9kg00qf 109 4 green green JJ cord-022526-j9kg00qf 109 5 and and CC cord-022526-j9kg00qf 109 6 may may MD cord-022526-j9kg00qf 109 7 contain contain VB cord-022526-j9kg00qf 109 8 foamy foamy JJ cord-022526-j9kg00qf 109 9 saliva saliva NN cord-022526-j9kg00qf 109 10 . . . cord-022526-j9kg00qf 110 1 The the DT cord-022526-j9kg00qf 110 2 volume volume NN cord-022526-j9kg00qf 110 3 obtained obtain VBN cord-022526-j9kg00qf 110 4 by by IN cord-022526-j9kg00qf 110 5 gastric gastric JJ cord-022526-j9kg00qf 110 6 lavage lavage NN cord-022526-j9kg00qf 110 7 is be VBZ cord-022526-j9kg00qf 110 8 usually usually RB cord-022526-j9kg00qf 110 9 less less JJR cord-022526-j9kg00qf 110 10 than than IN cord-022526-j9kg00qf 110 11 4 4 CD cord-022526-j9kg00qf 110 12 L. L. NNP cord-022526-j9kg00qf 110 13 Large large JJ cord-022526-j9kg00qf 110 14 volumes volume NNS cord-022526-j9kg00qf 110 15 of of IN cord-022526-j9kg00qf 110 16 fluid fluid NN cord-022526-j9kg00qf 110 17 ( ( -LRB- cord-022526-j9kg00qf 110 18 > > NFP cord-022526-j9kg00qf 110 19 8 8 CD cord-022526-j9kg00qf 110 20 to to TO cord-022526-j9kg00qf 110 21 10 10 CD cord-022526-j9kg00qf 110 22 L l NN cord-022526-j9kg00qf 110 23 ) ) -RRB- cord-022526-j9kg00qf 110 24 accumulate accumulate VBP cord-022526-j9kg00qf 110 25 in in IN cord-022526-j9kg00qf 110 26 the the DT cord-022526-j9kg00qf 110 27 stomach stomach NN cord-022526-j9kg00qf 110 28 of of IN cord-022526-j9kg00qf 110 29 horses horse NNS cord-022526-j9kg00qf 110 30 with with IN cord-022526-j9kg00qf 110 31 proximal proximal JJ cord-022526-j9kg00qf 110 32 enteritis enteritis NN cord-022526-j9kg00qf 110 33 , , , cord-022526-j9kg00qf 110 34 and and CC cord-022526-j9kg00qf 110 35 the the DT cord-022526-j9kg00qf 110 36 fluid fluid NN cord-022526-j9kg00qf 110 37 is be VBZ cord-022526-j9kg00qf 110 38 foul foul JJ cord-022526-j9kg00qf 110 39 smelling smell VBG cord-022526-j9kg00qf 110 40 and and CC cord-022526-j9kg00qf 110 41 often often RB cord-022526-j9kg00qf 110 42 has have VBZ cord-022526-j9kg00qf 110 43 an an DT cord-022526-j9kg00qf 110 44 orange orange NN cord-022526-j9kg00qf 110 45 to to IN cord-022526-j9kg00qf 110 46 yellow yellow JJ cord-022526-j9kg00qf 110 47 discoloration discoloration NN cord-022526-j9kg00qf 110 48 . . . cord-022526-j9kg00qf 111 1 If if IN cord-022526-j9kg00qf 111 2 one one CD cord-022526-j9kg00qf 111 3 suspects suspect NNS cord-022526-j9kg00qf 111 4 proximal proximal JJ cord-022526-j9kg00qf 111 5 enteritis enteritis NN cord-022526-j9kg00qf 111 6 , , , cord-022526-j9kg00qf 111 7 one one PRP cord-022526-j9kg00qf 111 8 can can MD cord-022526-j9kg00qf 111 9 submit submit VB cord-022526-j9kg00qf 111 10 the the DT cord-022526-j9kg00qf 111 11 fluid fluid NN cord-022526-j9kg00qf 111 12 for for IN cord-022526-j9kg00qf 111 13 culture culture NN cord-022526-j9kg00qf 111 14 and and CC cord-022526-j9kg00qf 111 15 Gram gram NN cord-022526-j9kg00qf 111 16 staining staining NN cord-022526-j9kg00qf 111 17 . . . cord-022526-j9kg00qf 112 1 Salmonella salmonella NN cord-022526-j9kg00qf 112 2 sp sp NN cord-022526-j9kg00qf 112 3 . . . cord-022526-j9kg00qf 113 1 and and CC cord-022526-j9kg00qf 113 2 Clostridium Clostridium NNP cord-022526-j9kg00qf 113 3 sp sp NNP cord-022526-j9kg00qf 113 4 . . . cord-022526-j9kg00qf 113 5 have have VBP cord-022526-j9kg00qf 113 6 been be VBN cord-022526-j9kg00qf 113 7 cultured culture VBN cord-022526-j9kg00qf 113 8 in in IN cord-022526-j9kg00qf 113 9 some some DT cord-022526-j9kg00qf 113 10 cases case NNS cord-022526-j9kg00qf 113 11 . . . cord-022526-j9kg00qf 114 1 Patients patient NNS cord-022526-j9kg00qf 114 2 with with IN cord-022526-j9kg00qf 114 3 postoperative postoperative JJ cord-022526-j9kg00qf 114 4 ileus ileus NN cord-022526-j9kg00qf 114 5 also also RB cord-022526-j9kg00qf 114 6 frequently frequently RB cord-022526-j9kg00qf 114 7 accumulate accumulate VBP cord-022526-j9kg00qf 114 8 large large JJ cord-022526-j9kg00qf 114 9 amounts amount NNS cord-022526-j9kg00qf 114 10 of of IN cord-022526-j9kg00qf 114 11 gastric gastric JJ cord-022526-j9kg00qf 114 12 fluid fluid NN cord-022526-j9kg00qf 114 13 . . . cord-022526-j9kg00qf 115 1 Horses horse NNS cord-022526-j9kg00qf 115 2 with with IN cord-022526-j9kg00qf 115 3 SECTION section NN cord-022526-j9kg00qf 115 4 13.1 13.1 CD cord-022526-j9kg00qf 115 5 Examination examination NN cord-022526-j9kg00qf 115 6 for for IN cord-022526-j9kg00qf 115 7 Disorders disorder NNS cord-022526-j9kg00qf 115 8 of of IN cord-022526-j9kg00qf 115 9 the the DT cord-022526-j9kg00qf 115 10 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 115 11 Tract Tract NNP cord-022526-j9kg00qf 115 12 strangulating strangulating JJ cord-022526-j9kg00qf 115 13 obstructions obstruction NNS cord-022526-j9kg00qf 115 14 or or CC cord-022526-j9kg00qf 115 15 luminal luminal JJ cord-022526-j9kg00qf 115 16 obstructions obstruction NNS cord-022526-j9kg00qf 115 17 often often RB cord-022526-j9kg00qf 115 18 accumulate accumulate VBP cord-022526-j9kg00qf 115 19 moderate moderate JJ cord-022526-j9kg00qf 115 20 amounts amount NNS cord-022526-j9kg00qf 115 21 of of IN cord-022526-j9kg00qf 115 22 gastric gastric JJ cord-022526-j9kg00qf 115 23 fluid fluid NN cord-022526-j9kg00qf 115 24 , , , cord-022526-j9kg00qf 115 25 but but CC cord-022526-j9kg00qf 115 26 the the DT cord-022526-j9kg00qf 115 27 amount amount NN cord-022526-j9kg00qf 115 28 is be VBZ cord-022526-j9kg00qf 115 29 generally generally RB cord-022526-j9kg00qf 115 30 less less JJR cord-022526-j9kg00qf 115 31 than than IN cord-022526-j9kg00qf 115 32 in in IN cord-022526-j9kg00qf 115 33 horses horse NNS cord-022526-j9kg00qf 115 34 with with IN cord-022526-j9kg00qf 115 35 proximal proximal JJ cord-022526-j9kg00qf 115 36 enteritis enteritis NN cord-022526-j9kg00qf 115 37 or or CC cord-022526-j9kg00qf 115 38 postoperative postoperative JJ cord-022526-j9kg00qf 115 39 ileus ileus NN cord-022526-j9kg00qf 115 40 . . . cord-022526-j9kg00qf 116 1 Hemorrhage hemorrhage NN cord-022526-j9kg00qf 116 2 in in IN cord-022526-j9kg00qf 116 3 the the DT cord-022526-j9kg00qf 116 4 gastric gastric JJ cord-022526-j9kg00qf 116 5 fluid fluid NN cord-022526-j9kg00qf 116 6 usually usually RB cord-022526-j9kg00qf 116 7 indicates indicate VBZ cord-022526-j9kg00qf 116 8 devitalized devitalize VBN cord-022526-j9kg00qf 116 9 small small JJ cord-022526-j9kg00qf 116 10 intestine intestine NN cord-022526-j9kg00qf 116 11 , , , cord-022526-j9kg00qf 116 12 stomach stomach NN cord-022526-j9kg00qf 116 13 wall wall NN cord-022526-j9kg00qf 116 14 , , , cord-022526-j9kg00qf 116 15 or or CC cord-022526-j9kg00qf 116 16 severe severe JJ cord-022526-j9kg00qf 116 17 gastric gastric JJ cord-022526-j9kg00qf 116 18 ulceration ulceration NN cord-022526-j9kg00qf 116 19 . . . cord-022526-j9kg00qf 117 1 Fluid fluid JJ cord-022526-j9kg00qf 117 2 with with IN cord-022526-j9kg00qf 117 3 large large JJ cord-022526-j9kg00qf 117 4 amounts amount NNS cord-022526-j9kg00qf 117 5 of of IN cord-022526-j9kg00qf 117 6 food food NN cord-022526-j9kg00qf 117 7 material material NN cord-022526-j9kg00qf 117 8 often often RB cord-022526-j9kg00qf 117 9 indicates indicate VBZ cord-022526-j9kg00qf 117 10 a a DT cord-022526-j9kg00qf 117 11 gastric gastric JJ cord-022526-j9kg00qf 117 12 impaction impaction NN cord-022526-j9kg00qf 117 13 , , , cord-022526-j9kg00qf 117 14 and and CC cord-022526-j9kg00qf 117 15 one one PRP cord-022526-j9kg00qf 117 16 should should MD cord-022526-j9kg00qf 117 17 lavage lavage VB cord-022526-j9kg00qf 117 18 the the DT cord-022526-j9kg00qf 117 19 stomach stomach NN cord-022526-j9kg00qf 117 20 until until IN cord-022526-j9kg00qf 117 21 obtaining obtain VBG cord-022526-j9kg00qf 117 22 no no DT cord-022526-j9kg00qf 117 23 more more RBR cord-022526-j9kg00qf 117 24 ingesta ingesta JJ cord-022526-j9kg00qf 117 25 . . . cord-022526-j9kg00qf 118 1 Horses horse NNS cord-022526-j9kg00qf 118 2 and and CC cord-022526-j9kg00qf 118 3 foals foal NNS cord-022526-j9kg00qf 118 4 with with IN cord-022526-j9kg00qf 118 5 chronic chronic JJ cord-022526-j9kg00qf 118 6 gastric gastric JJ cord-022526-j9kg00qf 118 7 ulceration ulceration NN cord-022526-j9kg00qf 118 8 in in IN cord-022526-j9kg00qf 118 9 the the DT cord-022526-j9kg00qf 118 10 glandular glandular JJ cord-022526-j9kg00qf 118 11 mucosa mucosa NN cord-022526-j9kg00qf 118 12 of of IN cord-022526-j9kg00qf 118 13 the the DT cord-022526-j9kg00qf 118 14 stomach stomach NN cord-022526-j9kg00qf 118 15 or or CC cord-022526-j9kg00qf 118 16 in in IN cord-022526-j9kg00qf 118 17 the the DT cord-022526-j9kg00qf 118 18 duodenum duodenum NN cord-022526-j9kg00qf 118 19 may may MD cord-022526-j9kg00qf 118 20 develop develop VB cord-022526-j9kg00qf 118 21 strictures stricture NNS cord-022526-j9kg00qf 118 22 and and CC cord-022526-j9kg00qf 118 23 have have VBP cord-022526-j9kg00qf 118 24 fluid fluid JJ cord-022526-j9kg00qf 118 25 accumulate accumulate NN cord-022526-j9kg00qf 118 26 in in IN cord-022526-j9kg00qf 118 27 the the DT cord-022526-j9kg00qf 118 28 stomach stomach NN cord-022526-j9kg00qf 118 29 . . . cord-022526-j9kg00qf 119 1 Endoscopy endoscopy NN cord-022526-j9kg00qf 119 2 or or CC cord-022526-j9kg00qf 119 3 contrast contrast NN cord-022526-j9kg00qf 119 4 radiography radiography NN cord-022526-j9kg00qf 119 5 aids aid NNS cord-022526-j9kg00qf 119 6 in in IN cord-022526-j9kg00qf 119 7 diagnosing diagnose VBG cord-022526-j9kg00qf 119 8 gastric gastric JJ cord-022526-j9kg00qf 119 9 outflow outflow JJ cord-022526-j9kg00qf 119 10 obstruction obstruction NN cord-022526-j9kg00qf 119 11 . . . cord-022526-j9kg00qf 120 1 Evaluation evaluation NN cord-022526-j9kg00qf 120 2 of of IN cord-022526-j9kg00qf 120 3 the the DT cord-022526-j9kg00qf 120 4 hemogram hemogram NN cord-022526-j9kg00qf 120 5 is be VBZ cord-022526-j9kg00qf 120 6 essential essential JJ cord-022526-j9kg00qf 120 7 when when WRB cord-022526-j9kg00qf 120 8 one one PRP cord-022526-j9kg00qf 120 9 assesses assess VBZ cord-022526-j9kg00qf 120 10 conditions condition NNS cord-022526-j9kg00qf 120 11 of of IN cord-022526-j9kg00qf 120 12 the the DT cord-022526-j9kg00qf 120 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 120 14 tract tract NN cord-022526-j9kg00qf 120 15 . . . cord-022526-j9kg00qf 121 1 However however RB cord-022526-j9kg00qf 121 2 , , , cord-022526-j9kg00qf 121 3 hematologic hematologic JJ cord-022526-j9kg00qf 121 4 alterations alteration NNS cord-022526-j9kg00qf 121 5 associated associate VBN cord-022526-j9kg00qf 121 6 with with IN cord-022526-j9kg00qf 121 7 diseases disease NNS cord-022526-j9kg00qf 121 8 of of IN cord-022526-j9kg00qf 121 9 the the DT cord-022526-j9kg00qf 121 10 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 121 11 tract tract NN cord-022526-j9kg00qf 121 12 are be VBP cord-022526-j9kg00qf 121 13 often often RB cord-022526-j9kg00qf 121 14 nonspecific nonspecific JJ cord-022526-j9kg00qf 121 15 , , , cord-022526-j9kg00qf 121 16 reflecting reflect VBG cord-022526-j9kg00qf 121 17 systemic systemic JJ cord-022526-j9kg00qf 121 18 response response NN cord-022526-j9kg00qf 121 19 to to IN cord-022526-j9kg00qf 121 20 inflammation inflammation NN cord-022526-j9kg00qf 121 21 , , , cord-022526-j9kg00qf 121 22 endotoxemia endotoxemia NN cord-022526-j9kg00qf 121 23 , , , cord-022526-j9kg00qf 121 24 or or CC cord-022526-j9kg00qf 121 25 sepsis sepsis NN cord-022526-j9kg00qf 121 26 . . . cord-022526-j9kg00qf 122 1 Neutrophilic Neutrophilic NNP cord-022526-j9kg00qf 122 2 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 122 3 and and CC cord-022526-j9kg00qf 122 4 normochromic normochromic NNP cord-022526-j9kg00qf 122 5 , , , cord-022526-j9kg00qf 122 6 normocytic normocytic JJ cord-022526-j9kg00qf 122 7 anemia anemia NN cord-022526-j9kg00qf 122 8 with with IN cord-022526-j9kg00qf 122 9 or or CC cord-022526-j9kg00qf 122 10 without without IN cord-022526-j9kg00qf 122 11 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 122 12 commonly commonly RB cord-022526-j9kg00qf 122 13 are be VBP cord-022526-j9kg00qf 122 14 associated associate VBN cord-022526-j9kg00qf 122 15 with with IN cord-022526-j9kg00qf 122 16 chronic chronic JJ cord-022526-j9kg00qf 122 17 inflammatory inflammatory JJ cord-022526-j9kg00qf 122 18 conditions condition NNS cord-022526-j9kg00qf 122 19 of of IN cord-022526-j9kg00qf 122 20 the the DT cord-022526-j9kg00qf 122 21 intestine intestine NN cord-022526-j9kg00qf 122 22 . . . cord-022526-j9kg00qf 123 1 Anemia anemia NN cord-022526-j9kg00qf 123 2 from from IN cord-022526-j9kg00qf 123 3 chronic chronic JJ cord-022526-j9kg00qf 123 4 blood blood NN cord-022526-j9kg00qf 123 5 loss loss NN cord-022526-j9kg00qf 123 6 occurs occur VBZ cord-022526-j9kg00qf 123 7 infrequently infrequently RB cord-022526-j9kg00qf 123 8 in in IN cord-022526-j9kg00qf 123 9 adult adult NN cord-022526-j9kg00qf 123 10 horses horse NNS cord-022526-j9kg00qf 123 11 because because IN cord-022526-j9kg00qf 123 12 of of IN cord-022526-j9kg00qf 123 13 the the DT cord-022526-j9kg00qf 123 14 large large JJ cord-022526-j9kg00qf 123 15 iron iron NN cord-022526-j9kg00qf 123 16 stores store NNS cord-022526-j9kg00qf 123 17 and and CC cord-022526-j9kg00qf 123 18 high high JJ cord-022526-j9kg00qf 123 19 concentrations concentration NNS cord-022526-j9kg00qf 123 20 of of IN cord-022526-j9kg00qf 123 21 iron iron NN cord-022526-j9kg00qf 123 22 in in IN cord-022526-j9kg00qf 123 23 their -PRON- PRP$ cord-022526-j9kg00qf 123 24 diet diet NN cord-022526-j9kg00qf 123 25 ; ; : cord-022526-j9kg00qf 123 26 usually usually RB cord-022526-j9kg00qf 123 27 anemia anemia NN cord-022526-j9kg00qf 123 28 follows follow VBZ cord-022526-j9kg00qf 123 29 chronic chronic JJ cord-022526-j9kg00qf 123 30 inflammation inflammation NN cord-022526-j9kg00qf 123 31 , , , cord-022526-j9kg00qf 123 32 as as IN cord-022526-j9kg00qf 123 33 do do VBP cord-022526-j9kg00qf 123 34 alterations alteration NNS cord-022526-j9kg00qf 123 35 in in IN cord-022526-j9kg00qf 123 36 the the DT cord-022526-j9kg00qf 123 37 leukon leukon NNP cord-022526-j9kg00qf 123 38 and and CC cord-022526-j9kg00qf 123 39 plasma plasma NN cord-022526-j9kg00qf 123 40 fibrinogen fibrinogen NN cord-022526-j9kg00qf 123 41 concentrations concentration NNS cord-022526-j9kg00qf 123 42 . . . cord-022526-j9kg00qf 124 1 Plasma plasma NN cord-022526-j9kg00qf 124 2 protein protein NN cord-022526-j9kg00qf 124 3 concentrations concentration NNS cord-022526-j9kg00qf 124 4 vary vary VBP cord-022526-j9kg00qf 124 5 depending depend VBG cord-022526-j9kg00qf 124 6 on on IN cord-022526-j9kg00qf 124 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 124 8 losses loss NNS cord-022526-j9kg00qf 124 9 of of IN cord-022526-j9kg00qf 124 10 albumin albumin NN cord-022526-j9kg00qf 124 11 and and CC cord-022526-j9kg00qf 124 12 globulin globulin NN cord-022526-j9kg00qf 124 13 and and CC cord-022526-j9kg00qf 124 14 elevation elevation NN cord-022526-j9kg00qf 124 15 of of IN cord-022526-j9kg00qf 124 16 globulin globulin NN cord-022526-j9kg00qf 124 17 concentration concentration NN cord-022526-j9kg00qf 124 18 from from IN cord-022526-j9kg00qf 124 19 antigenic antigenic JJ cord-022526-j9kg00qf 124 20 stimulation stimulation NN cord-022526-j9kg00qf 124 21 . . . cord-022526-j9kg00qf 125 1 Protein protein NN cord-022526-j9kg00qf 125 2 - - HYPH cord-022526-j9kg00qf 125 3 losing lose VBG cord-022526-j9kg00qf 125 4 enteropathies enteropathy NNS cord-022526-j9kg00qf 125 5 may may MD cord-022526-j9kg00qf 125 6 manifest manifest VB cord-022526-j9kg00qf 125 7 predominantly predominantly RB cord-022526-j9kg00qf 125 8 as as IN cord-022526-j9kg00qf 125 9 a a DT cord-022526-j9kg00qf 125 10 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 125 11 or or CC cord-022526-j9kg00qf 125 12 may may MD cord-022526-j9kg00qf 125 13 have have VB cord-022526-j9kg00qf 125 14 a a DT cord-022526-j9kg00qf 125 15 concurrent concurrent JJ cord-022526-j9kg00qf 125 16 hypoglobulinemia hypoglobulinemia NN cord-022526-j9kg00qf 125 17 . . . cord-022526-j9kg00qf 126 1 Immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 126 2 quantification quantification NN cord-022526-j9kg00qf 126 3 can can MD cord-022526-j9kg00qf 126 4 be be VB cord-022526-j9kg00qf 126 5 useful useful JJ cord-022526-j9kg00qf 126 6 in in IN cord-022526-j9kg00qf 126 7 selected select VBN cord-022526-j9kg00qf 126 8 cases case NNS cord-022526-j9kg00qf 126 9 ; ; : cord-022526-j9kg00qf 126 10 immunosuppression immunosuppression NN cord-022526-j9kg00qf 126 11 with with IN cord-022526-j9kg00qf 126 12 low low JJ cord-022526-j9kg00qf 126 13 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 126 14 M M NNP cord-022526-j9kg00qf 126 15 concentration concentration NN cord-022526-j9kg00qf 126 16 has have VBZ cord-022526-j9kg00qf 126 17 been be VBN cord-022526-j9kg00qf 126 18 shown show VBN cord-022526-j9kg00qf 126 19 to to TO cord-022526-j9kg00qf 126 20 occur occur VB cord-022526-j9kg00qf 126 21 in in IN cord-022526-j9kg00qf 126 22 some some DT cord-022526-j9kg00qf 126 23 cases case NNS cord-022526-j9kg00qf 126 24 of of IN cord-022526-j9kg00qf 126 25 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 126 26 . . . cord-022526-j9kg00qf 127 1 10 10 CD cord-022526-j9kg00qf 127 2 Parasitic parasitic JJ cord-022526-j9kg00qf 127 3 infections infection NNS cord-022526-j9kg00qf 127 4 , , , cord-022526-j9kg00qf 127 5 especially especially RB cord-022526-j9kg00qf 127 6 strongylosis strongylosis NNP cord-022526-j9kg00qf 127 7 , , , cord-022526-j9kg00qf 127 8 may may MD cord-022526-j9kg00qf 127 9 be be VB cord-022526-j9kg00qf 127 10 characterized characterize VBN cord-022526-j9kg00qf 127 11 by by IN cord-022526-j9kg00qf 127 12 elevated elevated JJ cord-022526-j9kg00qf 127 13 serum serum NN cord-022526-j9kg00qf 127 14 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 127 15 G(T G(T NNP cord-022526-j9kg00qf 127 16 ) ) -RRB- cord-022526-j9kg00qf 127 17 concentration concentration NN cord-022526-j9kg00qf 127 18 . . . cord-022526-j9kg00qf 128 1 11 11 CD cord-022526-j9kg00qf 129 1 Significant significant JJ cord-022526-j9kg00qf 129 2 alterations alteration NNS cord-022526-j9kg00qf 129 3 of of IN cord-022526-j9kg00qf 129 4 the the DT cord-022526-j9kg00qf 129 5 hemogram hemogram NN cord-022526-j9kg00qf 129 6 do do VBP cord-022526-j9kg00qf 129 7 not not RB cord-022526-j9kg00qf 129 8 accompany accompany VB cord-022526-j9kg00qf 129 9 acute acute JJ cord-022526-j9kg00qf 129 10 disease disease NN cord-022526-j9kg00qf 129 11 of of IN cord-022526-j9kg00qf 129 12 the the DT cord-022526-j9kg00qf 129 13 intestine intestine NN cord-022526-j9kg00qf 129 14 unless unless IN cord-022526-j9kg00qf 129 15 severe severe JJ cord-022526-j9kg00qf 129 16 inflammation inflammation NN cord-022526-j9kg00qf 129 17 , , , cord-022526-j9kg00qf 129 18 dehydration dehydration NN cord-022526-j9kg00qf 129 19 , , , cord-022526-j9kg00qf 129 20 endotoxemia endotoxemia NN cord-022526-j9kg00qf 129 21 , , , cord-022526-j9kg00qf 129 22 or or CC cord-022526-j9kg00qf 129 23 sepsis sepsis NN cord-022526-j9kg00qf 129 24 is be VBZ cord-022526-j9kg00qf 129 25 present present JJ cord-022526-j9kg00qf 129 26 . . . cord-022526-j9kg00qf 130 1 During during IN cord-022526-j9kg00qf 130 2 the the DT cord-022526-j9kg00qf 130 3 early early JJ cord-022526-j9kg00qf 130 4 stages stage NNS cord-022526-j9kg00qf 130 5 of of IN cord-022526-j9kg00qf 130 6 endotoxemia endotoxemia NN cord-022526-j9kg00qf 130 7 , , , cord-022526-j9kg00qf 130 8 elevations elevation NNS cord-022526-j9kg00qf 130 9 in in IN cord-022526-j9kg00qf 130 10 circulating circulate VBG cord-022526-j9kg00qf 130 11 concentrations concentration NNS cord-022526-j9kg00qf 130 12 of of IN cord-022526-j9kg00qf 130 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 130 14 mediators mediator NNS cord-022526-j9kg00qf 130 15 , , , cord-022526-j9kg00qf 130 16 epinephrine epinephrine NN cord-022526-j9kg00qf 130 17 , , , cord-022526-j9kg00qf 130 18 and and CC cord-022526-j9kg00qf 130 19 cortisol cortisol NN cord-022526-j9kg00qf 130 20 produce produce VBP cord-022526-j9kg00qf 130 21 characteristic characteristic JJ cord-022526-j9kg00qf 130 22 changes change NNS cord-022526-j9kg00qf 130 23 in in IN cord-022526-j9kg00qf 130 24 the the DT cord-022526-j9kg00qf 130 25 hemogram hemogram NN cord-022526-j9kg00qf 130 26 . . . cord-022526-j9kg00qf 131 1 Leukopenia leukopenia UH cord-022526-j9kg00qf 131 2 , , , cord-022526-j9kg00qf 131 3 with with IN cord-022526-j9kg00qf 131 4 neutropenia neutropenia NN cord-022526-j9kg00qf 131 5 and and CC cord-022526-j9kg00qf 131 6 a a DT cord-022526-j9kg00qf 131 7 left left JJ cord-022526-j9kg00qf 131 8 shift shift NN cord-022526-j9kg00qf 131 9 , , , cord-022526-j9kg00qf 131 10 toxic toxic JJ cord-022526-j9kg00qf 131 11 changes change NNS cord-022526-j9kg00qf 131 12 in in IN cord-022526-j9kg00qf 131 13 the the DT cord-022526-j9kg00qf 131 14 neutrophil neutrophil NN cord-022526-j9kg00qf 131 15 cytoplasm cytoplasm NN cord-022526-j9kg00qf 131 16 , , , cord-022526-j9kg00qf 131 17 and and CC cord-022526-j9kg00qf 131 18 lymphopenia lymphopenia NNP cord-022526-j9kg00qf 131 19 occur occur VBP cord-022526-j9kg00qf 131 20 commonly commonly RB cord-022526-j9kg00qf 131 21 . . . cord-022526-j9kg00qf 132 1 12 12 CD cord-022526-j9kg00qf 132 2 Hemoconcentration Hemoconcentration NNP cord-022526-j9kg00qf 132 3 and and CC cord-022526-j9kg00qf 132 4 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 132 5 are be VBP cord-022526-j9kg00qf 132 6 also also RB cord-022526-j9kg00qf 132 7 common common JJ cord-022526-j9kg00qf 132 8 . . . cord-022526-j9kg00qf 133 1 Thrombocytopenia Thrombocytopenia NNP cord-022526-j9kg00qf 133 2 and and CC cord-022526-j9kg00qf 133 3 other other JJ cord-022526-j9kg00qf 133 4 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 133 5 are be VBP cord-022526-j9kg00qf 133 6 also also RB cord-022526-j9kg00qf 133 7 features feature NNS cord-022526-j9kg00qf 133 8 of of IN cord-022526-j9kg00qf 133 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 133 10 . . . cord-022526-j9kg00qf 134 1 Indeed indeed RB cord-022526-j9kg00qf 134 2 , , , cord-022526-j9kg00qf 134 3 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 134 4 may may MD cord-022526-j9kg00qf 134 5 be be VB cord-022526-j9kg00qf 134 6 the the DT cord-022526-j9kg00qf 134 7 earliest early JJS cord-022526-j9kg00qf 134 8 indicator indicator NN cord-022526-j9kg00qf 134 9 of of IN cord-022526-j9kg00qf 134 10 sepsis sepsis NN cord-022526-j9kg00qf 134 11 . . . cord-022526-j9kg00qf 135 1 13 13 CD cord-022526-j9kg00qf 135 2 Endotoxemia Endotoxemia NNP cord-022526-j9kg00qf 135 3 and and CC cord-022526-j9kg00qf 135 4 circulating circulate VBG cord-022526-j9kg00qf 135 5 mediators mediator NNS cord-022526-j9kg00qf 135 6 of of IN cord-022526-j9kg00qf 135 7 inflammation inflammation NN cord-022526-j9kg00qf 135 8 activate activate VBP cord-022526-j9kg00qf 135 9 the the DT cord-022526-j9kg00qf 135 10 coagulation coagulation NN cord-022526-j9kg00qf 135 11 cascade cascade NN cord-022526-j9kg00qf 135 12 , , , cord-022526-j9kg00qf 135 13 causing cause VBG cord-022526-j9kg00qf 135 14 a a DT cord-022526-j9kg00qf 135 15 hypercoagulable hypercoagulable JJ cord-022526-j9kg00qf 135 16 state state NN cord-022526-j9kg00qf 135 17 that that WDT cord-022526-j9kg00qf 135 18 can can MD cord-022526-j9kg00qf 135 19 lead lead VB cord-022526-j9kg00qf 135 20 to to IN cord-022526-j9kg00qf 135 21 consumption consumption NN cord-022526-j9kg00qf 135 22 of of IN cord-022526-j9kg00qf 135 23 coagulation coagulation NN cord-022526-j9kg00qf 135 24 factors factor NNS cord-022526-j9kg00qf 135 25 and and CC cord-022526-j9kg00qf 135 26 coagulation coagulation NN cord-022526-j9kg00qf 135 27 defects defect NNS cord-022526-j9kg00qf 135 28 manifested manifest VBN cord-022526-j9kg00qf 135 29 as as IN cord-022526-j9kg00qf 135 30 elevated elevated JJ cord-022526-j9kg00qf 135 31 prothrombin prothrombin NN cord-022526-j9kg00qf 135 32 time time NN cord-022526-j9kg00qf 135 33 , , , cord-022526-j9kg00qf 135 34 partial partial JJ cord-022526-j9kg00qf 135 35 thromboplastin thromboplastin NNP cord-022526-j9kg00qf 135 36 time time NN cord-022526-j9kg00qf 135 37 , , , cord-022526-j9kg00qf 135 38 fibrin fibrin NN cord-022526-j9kg00qf 135 39 degradation degradation NN cord-022526-j9kg00qf 135 40 products product NNS cord-022526-j9kg00qf 135 41 , , , cord-022526-j9kg00qf 135 42 and and CC cord-022526-j9kg00qf 135 43 bleeding bleed VBG cord-022526-j9kg00qf 135 44 time time NN cord-022526-j9kg00qf 135 45 , , , cord-022526-j9kg00qf 135 46 and and CC cord-022526-j9kg00qf 135 47 reduced reduced JJ cord-022526-j9kg00qf 135 48 activity activity NN cord-022526-j9kg00qf 135 49 of of IN cord-022526-j9kg00qf 135 50 antithrombin antithrombin NN cord-022526-j9kg00qf 135 51 III III NNP cord-022526-j9kg00qf 135 52 . . . cord-022526-j9kg00qf 136 1 [ [ -LRB- cord-022526-j9kg00qf 136 2 14 14 CD cord-022526-j9kg00qf 136 3 ] ] -RRB- cord-022526-j9kg00qf 136 4 [ [ -LRB- cord-022526-j9kg00qf 136 5 15 15 CD cord-022526-j9kg00qf 136 6 ] ] -RRB- cord-022526-j9kg00qf 136 7 [ [ -LRB- cord-022526-j9kg00qf 136 8 16 16 CD cord-022526-j9kg00qf 136 9 ] ] -RRB- cord-022526-j9kg00qf 137 1 Neutrophilic Neutrophilic NNP cord-022526-j9kg00qf 137 2 leukocytosis leukocytosis NN cord-022526-j9kg00qf 137 3 occurs occur VBZ cord-022526-j9kg00qf 137 4 during during IN cord-022526-j9kg00qf 137 5 the the DT cord-022526-j9kg00qf 137 6 later later JJ cord-022526-j9kg00qf 137 7 stages stage NNS cord-022526-j9kg00qf 137 8 of of IN cord-022526-j9kg00qf 137 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 137 10 . . . cord-022526-j9kg00qf 138 1 14 14 CD cord-022526-j9kg00qf 139 1 The the DT cord-022526-j9kg00qf 139 2 most most RBS cord-022526-j9kg00qf 139 3 common common JJ cord-022526-j9kg00qf 139 4 serum serum NN cord-022526-j9kg00qf 139 5 biochemical biochemical JJ cord-022526-j9kg00qf 139 6 abnormalities abnormality NNS cord-022526-j9kg00qf 139 7 with with IN cord-022526-j9kg00qf 139 8 diseases disease NNS cord-022526-j9kg00qf 139 9 of of IN cord-022526-j9kg00qf 139 10 the the DT cord-022526-j9kg00qf 139 11 large large JJ cord-022526-j9kg00qf 139 12 or or CC cord-022526-j9kg00qf 139 13 small small JJ cord-022526-j9kg00qf 139 14 intestine intestine NN cord-022526-j9kg00qf 139 15 are be VBP cord-022526-j9kg00qf 139 16 electrolyte electrolyte JJ cord-022526-j9kg00qf 139 17 imbalances imbalance NNS cord-022526-j9kg00qf 139 18 . . . cord-022526-j9kg00qf 140 1 Serum serum NN cord-022526-j9kg00qf 140 2 calcium calcium NN cord-022526-j9kg00qf 140 3 concentrations concentration NNS cord-022526-j9kg00qf 140 4 are be VBP cord-022526-j9kg00qf 140 5 often often RB cord-022526-j9kg00qf 140 6 low low JJ cord-022526-j9kg00qf 140 7 with with IN cord-022526-j9kg00qf 140 8 strangulating strangulating JJ cord-022526-j9kg00qf 140 9 obstructions obstruction NNS cord-022526-j9kg00qf 140 10 and and CC cord-022526-j9kg00qf 140 11 acute acute JJ cord-022526-j9kg00qf 140 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 140 13 diseases disease NNS cord-022526-j9kg00qf 140 14 . . . cord-022526-j9kg00qf 141 1 17 17 CD cord-022526-j9kg00qf 141 2 Inflammation inflammation NN cord-022526-j9kg00qf 141 3 of of IN cord-022526-j9kg00qf 141 4 the the DT cord-022526-j9kg00qf 141 5 mucosa mucosa NN cord-022526-j9kg00qf 141 6 can can MD cord-022526-j9kg00qf 141 7 disrupt disrupt VB cord-022526-j9kg00qf 141 8 electrolyte electrolyte JJ cord-022526-j9kg00qf 141 9 fluxes flux NNS cord-022526-j9kg00qf 141 10 severely severely RB cord-022526-j9kg00qf 141 11 . . . cord-022526-j9kg00qf 142 1 Diarrhea diarrhea JJ cord-022526-j9kg00qf 142 2 or or CC cord-022526-j9kg00qf 142 3 gastric gastric JJ cord-022526-j9kg00qf 142 4 reflux reflux NN cord-022526-j9kg00qf 142 5 greatly greatly RB cord-022526-j9kg00qf 142 6 exacerbates exacerbate VBZ cord-022526-j9kg00qf 142 7 the the DT cord-022526-j9kg00qf 142 8 loss loss NN cord-022526-j9kg00qf 142 9 of of IN cord-022526-j9kg00qf 142 10 sodium sodium NN cord-022526-j9kg00qf 142 11 , , , cord-022526-j9kg00qf 142 12 potassium potassium NN cord-022526-j9kg00qf 142 13 , , , cord-022526-j9kg00qf 142 14 calcium calcium NN cord-022526-j9kg00qf 142 15 , , , cord-022526-j9kg00qf 142 16 magnesium magnesium NN cord-022526-j9kg00qf 142 17 and and CC cord-022526-j9kg00qf 142 18 bicarbonate bicarbonate NN cord-022526-j9kg00qf 142 19 . . . cord-022526-j9kg00qf 143 1 Ischemia ischemia NN cord-022526-j9kg00qf 143 2 of of IN cord-022526-j9kg00qf 143 3 the the DT cord-022526-j9kg00qf 143 4 intestine intestine NN cord-022526-j9kg00qf 143 5 causing cause VBG cord-022526-j9kg00qf 143 6 hypoxia hypoxia NN cord-022526-j9kg00qf 143 7 and and CC cord-022526-j9kg00qf 143 8 cellular cellular JJ cord-022526-j9kg00qf 143 9 damage damage NN cord-022526-j9kg00qf 143 10 may may MD cord-022526-j9kg00qf 143 11 be be VB cord-022526-j9kg00qf 143 12 reflected reflect VBN cord-022526-j9kg00qf 143 13 by by IN cord-022526-j9kg00qf 143 14 an an DT cord-022526-j9kg00qf 143 15 elevated elevated JJ cord-022526-j9kg00qf 143 16 serum serum NN cord-022526-j9kg00qf 143 17 phosphate phosphate NN cord-022526-j9kg00qf 143 18 concentration concentration NN cord-022526-j9kg00qf 143 19 resulting result VBG cord-022526-j9kg00qf 143 20 from from IN cord-022526-j9kg00qf 143 21 phosphate phosphate NN cord-022526-j9kg00qf 143 22 leakage leakage NN cord-022526-j9kg00qf 143 23 from from IN cord-022526-j9kg00qf 143 24 damaged damage VBN cord-022526-j9kg00qf 143 25 cells cell NNS cord-022526-j9kg00qf 143 26 . . . cord-022526-j9kg00qf 144 1 18 18 CD cord-022526-j9kg00qf 144 2 Ischemia ischemia NN cord-022526-j9kg00qf 144 3 and and CC cord-022526-j9kg00qf 144 4 cellular cellular JJ cord-022526-j9kg00qf 144 5 hypoxia hypoxia NN cord-022526-j9kg00qf 144 6 in in IN cord-022526-j9kg00qf 144 7 any any DT cord-022526-j9kg00qf 144 8 segment segment NN cord-022526-j9kg00qf 144 9 of of IN cord-022526-j9kg00qf 144 10 the the DT cord-022526-j9kg00qf 144 11 intestine intestine NN cord-022526-j9kg00qf 144 12 also also RB cord-022526-j9kg00qf 144 13 causes cause VBZ cord-022526-j9kg00qf 144 14 a a DT cord-022526-j9kg00qf 144 15 shift shift NN cord-022526-j9kg00qf 144 16 in in IN cord-022526-j9kg00qf 144 17 energy energy NN cord-022526-j9kg00qf 144 18 metabolism metabolism NN cord-022526-j9kg00qf 144 19 to to IN cord-022526-j9kg00qf 144 20 anaerobic anaerobic JJ cord-022526-j9kg00qf 144 21 glycolysis glycolysis NN cord-022526-j9kg00qf 144 22 , , , cord-022526-j9kg00qf 144 23 resulting result VBG cord-022526-j9kg00qf 144 24 in in IN cord-022526-j9kg00qf 144 25 increased increase VBN cord-022526-j9kg00qf 144 26 production production NN cord-022526-j9kg00qf 144 27 of of IN cord-022526-j9kg00qf 144 28 lactate lactate NN cord-022526-j9kg00qf 144 29 and and CC cord-022526-j9kg00qf 144 30 elevated elevated JJ cord-022526-j9kg00qf 144 31 serum serum NN cord-022526-j9kg00qf 144 32 lactate lactate NN cord-022526-j9kg00qf 144 33 concentration concentration NN cord-022526-j9kg00qf 144 34 . . . cord-022526-j9kg00qf 145 1 Reduced reduce VBN cord-022526-j9kg00qf 145 2 perfusion perfusion NN cord-022526-j9kg00qf 145 3 of of IN cord-022526-j9kg00qf 145 4 peripheral peripheral JJ cord-022526-j9kg00qf 145 5 tissues tissue NNS cord-022526-j9kg00qf 145 6 from from IN cord-022526-j9kg00qf 145 7 hypotensive hypotensive JJ cord-022526-j9kg00qf 145 8 shock shock NN cord-022526-j9kg00qf 145 9 and and CC cord-022526-j9kg00qf 145 10 intestinal intestinal JJ cord-022526-j9kg00qf 145 11 ischemia ischemia NN cord-022526-j9kg00qf 145 12 can can MD cord-022526-j9kg00qf 145 13 cause cause VB cord-022526-j9kg00qf 145 14 elevations elevation NNS cord-022526-j9kg00qf 145 15 in in IN cord-022526-j9kg00qf 145 16 serum serum NN cord-022526-j9kg00qf 145 17 lactate lactate NN cord-022526-j9kg00qf 145 18 . . . cord-022526-j9kg00qf 146 1 However however RB cord-022526-j9kg00qf 146 2 , , , cord-022526-j9kg00qf 146 3 obstruction obstruction NN cord-022526-j9kg00qf 146 4 of of IN cord-022526-j9kg00qf 146 5 the the DT cord-022526-j9kg00qf 146 6 intestine intestine NN cord-022526-j9kg00qf 146 7 during during IN cord-022526-j9kg00qf 146 8 ischemia ischemia NN cord-022526-j9kg00qf 146 9 may may MD cord-022526-j9kg00qf 146 10 result result VB cord-022526-j9kg00qf 146 11 in in IN cord-022526-j9kg00qf 146 12 absorption absorption NN cord-022526-j9kg00qf 146 13 of of IN cord-022526-j9kg00qf 146 14 lactate lactate NN cord-022526-j9kg00qf 146 15 from from IN cord-022526-j9kg00qf 146 16 the the DT cord-022526-j9kg00qf 146 17 lumen lumen NN cord-022526-j9kg00qf 146 18 . . . cord-022526-j9kg00qf 147 1 19 19 CD cord-022526-j9kg00qf 147 2 , , , cord-022526-j9kg00qf 147 3 20 20 CD cord-022526-j9kg00qf 147 4 Anion anion NN cord-022526-j9kg00qf 147 5 gap gap NN cord-022526-j9kg00qf 147 6 is be VBZ cord-022526-j9kg00qf 147 7 an an DT cord-022526-j9kg00qf 147 8 indirect indirect JJ cord-022526-j9kg00qf 147 9 measurement measurement NN cord-022526-j9kg00qf 147 10 of of IN cord-022526-j9kg00qf 147 11 organic organic JJ cord-022526-j9kg00qf 147 12 acid acid NN cord-022526-j9kg00qf 147 13 production production NN cord-022526-j9kg00qf 147 14 during during IN cord-022526-j9kg00qf 147 15 states state NNS cord-022526-j9kg00qf 147 16 of of IN cord-022526-j9kg00qf 147 17 tissue tissue NN cord-022526-j9kg00qf 147 18 hypoxia hypoxia NN cord-022526-j9kg00qf 147 19 and and CC cord-022526-j9kg00qf 147 20 is be VBZ cord-022526-j9kg00qf 147 21 a a DT cord-022526-j9kg00qf 147 22 reasonable reasonable JJ cord-022526-j9kg00qf 147 23 estimate estimate NN cord-022526-j9kg00qf 147 24 of of IN cord-022526-j9kg00qf 147 25 serum serum NN cord-022526-j9kg00qf 147 26 lactate lactate NN cord-022526-j9kg00qf 147 27 concentration concentration NN cord-022526-j9kg00qf 147 28 . . . cord-022526-j9kg00qf 148 1 20 20 CD cord-022526-j9kg00qf 148 2 Metabolic metabolic JJ cord-022526-j9kg00qf 148 3 acidosis acidosis NN cord-022526-j9kg00qf 148 4 may may MD cord-022526-j9kg00qf 148 5 accompany accompany VB cord-022526-j9kg00qf 148 6 lactic lactic JJ cord-022526-j9kg00qf 148 7 acidemia acidemia NN cord-022526-j9kg00qf 148 8 , , , cord-022526-j9kg00qf 148 9 but but CC cord-022526-j9kg00qf 148 10 an an DT cord-022526-j9kg00qf 148 11 inconsistent inconsistent JJ cord-022526-j9kg00qf 148 12 association association NN cord-022526-j9kg00qf 148 13 exists exist VBZ cord-022526-j9kg00qf 148 14 between between IN cord-022526-j9kg00qf 148 15 the the DT cord-022526-j9kg00qf 148 16 two two CD cord-022526-j9kg00qf 148 17 , , , cord-022526-j9kg00qf 148 18 especially especially RB cord-022526-j9kg00qf 148 19 when when WRB cord-022526-j9kg00qf 148 20 mixed mixed JJ cord-022526-j9kg00qf 148 21 acid acid NN cord-022526-j9kg00qf 148 22 - - HYPH cord-022526-j9kg00qf 148 23 base base NN cord-022526-j9kg00qf 148 24 imbalances imbalance NNS cord-022526-j9kg00qf 148 25 are be VBP cord-022526-j9kg00qf 148 26 present present JJ cord-022526-j9kg00qf 148 27 . . . cord-022526-j9kg00qf 149 1 20 20 CD cord-022526-j9kg00qf 149 2 , , , cord-022526-j9kg00qf 149 3 21 21 CD cord-022526-j9kg00qf 149 4 Elevations elevation NNS cord-022526-j9kg00qf 149 5 of of IN cord-022526-j9kg00qf 149 6 hepatic hepatic JJ cord-022526-j9kg00qf 149 7 enzymes enzyme NNS cord-022526-j9kg00qf 149 8 , , , cord-022526-j9kg00qf 149 9 specifically specifically RB cord-022526-j9kg00qf 149 10 γ γ NN cord-022526-j9kg00qf 149 11 - - HYPH cord-022526-j9kg00qf 149 12 glutamyltransferase glutamyltransferase NNP cord-022526-j9kg00qf 149 13 , , , cord-022526-j9kg00qf 149 14 may may MD cord-022526-j9kg00qf 149 15 occur occur VB cord-022526-j9kg00qf 149 16 with with IN cord-022526-j9kg00qf 149 17 large large JJ cord-022526-j9kg00qf 149 18 colon colon NN cord-022526-j9kg00qf 149 19 displacements displacement NNS cord-022526-j9kg00qf 149 20 , , , cord-022526-j9kg00qf 149 21 duodenal duodenal JJ cord-022526-j9kg00qf 149 22 strictures stricture NNS cord-022526-j9kg00qf 149 23 , , , cord-022526-j9kg00qf 149 24 or or CC cord-022526-j9kg00qf 149 25 anterior anterior JJ cord-022526-j9kg00qf 149 26 enteritis enteritis NN cord-022526-j9kg00qf 149 27 . . . cord-022526-j9kg00qf 150 1 Relative relative JJ cord-022526-j9kg00qf 150 2 polycythemia polycythemia NN cord-022526-j9kg00qf 150 3 from from IN cord-022526-j9kg00qf 150 4 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 150 5 or or CC cord-022526-j9kg00qf 150 6 splenic splenic JJ cord-022526-j9kg00qf 150 7 contraction contraction NN cord-022526-j9kg00qf 150 8 and and CC cord-022526-j9kg00qf 150 9 changes change NNS cord-022526-j9kg00qf 150 10 in in IN cord-022526-j9kg00qf 150 11 red red JJ cord-022526-j9kg00qf 150 12 blood blood NN cord-022526-j9kg00qf 150 13 cell cell NN cord-022526-j9kg00qf 150 14 deformability deformability NN cord-022526-j9kg00qf 150 15 from from IN cord-022526-j9kg00qf 150 16 hypoxia hypoxia NN cord-022526-j9kg00qf 150 17 or or CC cord-022526-j9kg00qf 150 18 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 150 19 may may MD cord-022526-j9kg00qf 150 20 increase increase VB cord-022526-j9kg00qf 150 21 blood blood NN cord-022526-j9kg00qf 150 22 viscosity viscosity NN cord-022526-j9kg00qf 150 23 . . . cord-022526-j9kg00qf 151 1 Blood blood NN cord-022526-j9kg00qf 151 2 viscosity viscosity NN cord-022526-j9kg00qf 151 3 increases increase NNS cord-022526-j9kg00qf 151 4 in in IN cord-022526-j9kg00qf 151 5 patients patient NNS cord-022526-j9kg00qf 151 6 with with IN cord-022526-j9kg00qf 151 7 acute acute JJ cord-022526-j9kg00qf 151 8 obstructive obstructive JJ cord-022526-j9kg00qf 151 9 disease disease NN cord-022526-j9kg00qf 151 10 . . . cord-022526-j9kg00qf 152 1 Hyperviscosity hyperviscosity NN cord-022526-j9kg00qf 152 2 reduces reduce VBZ cord-022526-j9kg00qf 152 3 perfusion perfusion NN cord-022526-j9kg00qf 152 4 of of IN cord-022526-j9kg00qf 152 5 capillary capillary JJ cord-022526-j9kg00qf 152 6 beds bed NNS cord-022526-j9kg00qf 152 7 , , , cord-022526-j9kg00qf 152 8 thereby thereby RB cord-022526-j9kg00qf 152 9 exacerbating exacerbate VBG cord-022526-j9kg00qf 152 10 ischemia ischemia NN cord-022526-j9kg00qf 152 11 and and CC cord-022526-j9kg00qf 152 12 tissue tissue NN cord-022526-j9kg00qf 152 13 hypoxia hypoxia NN cord-022526-j9kg00qf 152 14 . . . cord-022526-j9kg00qf 153 1 22 22 CD cord-022526-j9kg00qf 153 2 Hyperviscosity Hyperviscosity NNP cord-022526-j9kg00qf 153 3 is be VBZ cord-022526-j9kg00qf 153 4 one one CD cord-022526-j9kg00qf 153 5 manifestation manifestation NN cord-022526-j9kg00qf 153 6 ( ( -LRB- cord-022526-j9kg00qf 153 7 along along IN cord-022526-j9kg00qf 153 8 with with IN cord-022526-j9kg00qf 153 9 lactic lactic JJ cord-022526-j9kg00qf 153 10 acidemia acidemia NN cord-022526-j9kg00qf 153 11 , , , cord-022526-j9kg00qf 153 12 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 153 13 , , , cord-022526-j9kg00qf 153 14 and and CC cord-022526-j9kg00qf 153 15 clinical clinical JJ cord-022526-j9kg00qf 153 16 signs sign NNS cord-022526-j9kg00qf 153 17 of of IN cord-022526-j9kg00qf 153 18 shock shock NN cord-022526-j9kg00qf 153 19 ) ) -RRB- cord-022526-j9kg00qf 153 20 of of IN cord-022526-j9kg00qf 153 21 the the DT cord-022526-j9kg00qf 153 22 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 153 23 events event NNS cord-022526-j9kg00qf 153 24 that that WDT cord-022526-j9kg00qf 153 25 take take VBP cord-022526-j9kg00qf 153 26 place place NN cord-022526-j9kg00qf 153 27 during during IN cord-022526-j9kg00qf 153 28 acute acute JJ cord-022526-j9kg00qf 153 29 inflammatory inflammatory JJ cord-022526-j9kg00qf 153 30 or or CC cord-022526-j9kg00qf 153 31 vascular vascular JJ cord-022526-j9kg00qf 153 32 injury injury NN cord-022526-j9kg00qf 153 33 to to IN cord-022526-j9kg00qf 153 34 the the DT cord-022526-j9kg00qf 153 35 large large JJ cord-022526-j9kg00qf 153 36 intestine intestine NN cord-022526-j9kg00qf 153 37 . . . cord-022526-j9kg00qf 154 1 Laboratory laboratory NN cord-022526-j9kg00qf 154 2 tests test NNS cord-022526-j9kg00qf 154 3 designed design VBN cord-022526-j9kg00qf 154 4 to to TO cord-022526-j9kg00qf 154 5 reflect reflect VB cord-022526-j9kg00qf 154 6 the the DT cord-022526-j9kg00qf 154 7 systemic systemic JJ cord-022526-j9kg00qf 154 8 effects effect NNS cord-022526-j9kg00qf 154 9 of of IN cord-022526-j9kg00qf 154 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 154 11 , , , cord-022526-j9kg00qf 154 12 ischemia ischemia NN cord-022526-j9kg00qf 154 13 , , , cord-022526-j9kg00qf 154 14 sepsis sepsis NN cord-022526-j9kg00qf 154 15 , , , cord-022526-j9kg00qf 154 16 and and CC cord-022526-j9kg00qf 154 17 shock shock NN cord-022526-j9kg00qf 154 18 are be VBP cord-022526-j9kg00qf 154 19 important important JJ cord-022526-j9kg00qf 154 20 to to TO cord-022526-j9kg00qf 154 21 design design VB cord-022526-j9kg00qf 154 22 therapeutic therapeutic JJ cord-022526-j9kg00qf 154 23 strategies strategy NNS cord-022526-j9kg00qf 154 24 , , , cord-022526-j9kg00qf 154 25 and and CC cord-022526-j9kg00qf 154 26 monitor monitor VB cord-022526-j9kg00qf 154 27 response response NN cord-022526-j9kg00qf 154 28 to to IN cord-022526-j9kg00qf 154 29 therapy therapy NN cord-022526-j9kg00qf 154 30 . . . cord-022526-j9kg00qf 155 1 Abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 155 2 and and CC cord-022526-j9kg00qf 155 3 analysis analysis NN cord-022526-j9kg00qf 155 4 of of IN cord-022526-j9kg00qf 155 5 peritoneal peritoneal JJ cord-022526-j9kg00qf 155 6 fluid fluid NN cord-022526-j9kg00qf 155 7 ( ( -LRB- cord-022526-j9kg00qf 155 8 PF PF NNP cord-022526-j9kg00qf 155 9 ) ) -RRB- cord-022526-j9kg00qf 155 10 is be VBZ cord-022526-j9kg00qf 155 11 a a DT cord-022526-j9kg00qf 155 12 diagnostic diagnostic JJ cord-022526-j9kg00qf 155 13 technique technique NN cord-022526-j9kg00qf 155 14 performed perform VBN cord-022526-j9kg00qf 155 15 on on IN cord-022526-j9kg00qf 155 16 many many JJ cord-022526-j9kg00qf 155 17 patients patient NNS cord-022526-j9kg00qf 155 18 with with IN cord-022526-j9kg00qf 155 19 disease disease NN cord-022526-j9kg00qf 155 20 of of IN cord-022526-j9kg00qf 155 21 the the DT cord-022526-j9kg00qf 155 22 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 155 23 tract tract NN cord-022526-j9kg00qf 155 24 . . . cord-022526-j9kg00qf 156 1 One one PRP cord-022526-j9kg00qf 156 2 can can MD cord-022526-j9kg00qf 156 3 quantitate quantitate VB cord-022526-j9kg00qf 156 4 cytologic cytologic JJ cord-022526-j9kg00qf 156 5 examination examination NN cord-022526-j9kg00qf 156 6 of of IN cord-022526-j9kg00qf 156 7 PF pf NN cord-022526-j9kg00qf 156 8 ; ; : cord-022526-j9kg00qf 156 9 white white JJ cord-022526-j9kg00qf 156 10 blood blood NN cord-022526-j9kg00qf 156 11 cell cell NN cord-022526-j9kg00qf 156 12 and and CC cord-022526-j9kg00qf 156 13 red red JJ cord-022526-j9kg00qf 156 14 blood blood NN cord-022526-j9kg00qf 156 15 cell cell NN cord-022526-j9kg00qf 156 16 counts count NNS cord-022526-j9kg00qf 156 17 ; ; : cord-022526-j9kg00qf 156 18 protein protein NN cord-022526-j9kg00qf 156 19 , , , cord-022526-j9kg00qf 156 20 fibrinogen fibrinogen NN cord-022526-j9kg00qf 156 21 , , , cord-022526-j9kg00qf 156 22 lactate lactate NN cord-022526-j9kg00qf 156 23 , , , cord-022526-j9kg00qf 156 24 phosphate phosphate NN cord-022526-j9kg00qf 156 25 , , , cord-022526-j9kg00qf 156 26 and and CC cord-022526-j9kg00qf 156 27 glucose glucose NN cord-022526-j9kg00qf 156 28 concentrations concentration NNS cord-022526-j9kg00qf 156 29 ; ; : cord-022526-j9kg00qf 156 30 lactate lactate NN cord-022526-j9kg00qf 156 31 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 156 32 , , , cord-022526-j9kg00qf 156 33 creatine creatine NN cord-022526-j9kg00qf 156 34 kinase kinase NN cord-022526-j9kg00qf 156 35 , , , cord-022526-j9kg00qf 156 36 and and CC cord-022526-j9kg00qf 156 37 alkaline alkaline JJ cord-022526-j9kg00qf 156 38 phosphatase phosphatase NN cord-022526-j9kg00qf 156 39 activity activity NN cord-022526-j9kg00qf 156 40 ; ; : cord-022526-j9kg00qf 156 41 and and CC cord-022526-j9kg00qf 157 1 pH. pH. NNP cord-022526-j9kg00qf 157 2 The the DT cord-022526-j9kg00qf 157 3 results result NNS cord-022526-j9kg00qf 157 4 of of IN cord-022526-j9kg00qf 157 5 PF PF NNP cord-022526-j9kg00qf 157 6 analysis analysis NN cord-022526-j9kg00qf 157 7 may may MD cord-022526-j9kg00qf 157 8 help help VB cord-022526-j9kg00qf 157 9 establish establish VB cord-022526-j9kg00qf 157 10 a a DT cord-022526-j9kg00qf 157 11 specific specific JJ cord-022526-j9kg00qf 157 12 diagnosis diagnosis NN cord-022526-j9kg00qf 157 13 but but CC cord-022526-j9kg00qf 157 14 more more RBR cord-022526-j9kg00qf 157 15 importantly importantly RB cord-022526-j9kg00qf 157 16 may may MD cord-022526-j9kg00qf 157 17 reflect reflect VB cord-022526-j9kg00qf 157 18 inflammatory inflammatory JJ cord-022526-j9kg00qf 157 19 , , , cord-022526-j9kg00qf 157 20 vascular vascular JJ cord-022526-j9kg00qf 157 21 , , , cord-022526-j9kg00qf 157 22 or or CC cord-022526-j9kg00qf 157 23 ischemic ischemic JJ cord-022526-j9kg00qf 157 24 injury injury NN cord-022526-j9kg00qf 157 25 to to IN cord-022526-j9kg00qf 157 26 the the DT cord-022526-j9kg00qf 157 27 intestine intestine NN cord-022526-j9kg00qf 157 28 requiring require VBG cord-022526-j9kg00qf 157 29 surgical surgical JJ cord-022526-j9kg00qf 157 30 intervention intervention NN cord-022526-j9kg00qf 157 31 . . . cord-022526-j9kg00qf 158 1 PF PF NNP cord-022526-j9kg00qf 158 2 reflects reflect VBZ cord-022526-j9kg00qf 158 3 a a DT cord-022526-j9kg00qf 158 4 sequence sequence NN cord-022526-j9kg00qf 158 5 of of IN cord-022526-j9kg00qf 158 6 events event NNS cord-022526-j9kg00qf 158 7 that that WDT cord-022526-j9kg00qf 158 8 takes take VBZ cord-022526-j9kg00qf 158 9 place place NN cord-022526-j9kg00qf 158 10 during during IN cord-022526-j9kg00qf 158 11 acute acute JJ cord-022526-j9kg00qf 158 12 vascular vascular JJ cord-022526-j9kg00qf 158 13 injury injury NN cord-022526-j9kg00qf 158 14 to to IN cord-022526-j9kg00qf 158 15 the the DT cord-022526-j9kg00qf 158 16 intestine intestine NN cord-022526-j9kg00qf 158 17 . . . cord-022526-j9kg00qf 159 1 The the DT cord-022526-j9kg00qf 159 2 PF PF NNP cord-022526-j9kg00qf 159 3 protein protein NN cord-022526-j9kg00qf 159 4 concentration concentration NN cord-022526-j9kg00qf 159 5 first first JJ cord-022526-j9kg00qf 159 6 increases increase NNS cord-022526-j9kg00qf 159 7 , , , cord-022526-j9kg00qf 159 8 followed follow VBN cord-022526-j9kg00qf 159 9 by by IN cord-022526-j9kg00qf 159 10 an an DT cord-022526-j9kg00qf 159 11 increase increase NN cord-022526-j9kg00qf 159 12 in in IN cord-022526-j9kg00qf 159 13 the the DT cord-022526-j9kg00qf 159 14 red red JJ cord-022526-j9kg00qf 159 15 blood blood NN cord-022526-j9kg00qf 159 16 cell cell NN cord-022526-j9kg00qf 159 17 count count NN cord-022526-j9kg00qf 159 18 and and CC cord-022526-j9kg00qf 159 19 fibrinogen fibrinogen NN cord-022526-j9kg00qf 159 20 concentration concentration NN cord-022526-j9kg00qf 159 21 . . . cord-022526-j9kg00qf 160 1 A a DT cord-022526-j9kg00qf 160 2 transudative transudative JJ cord-022526-j9kg00qf 160 3 process process NN cord-022526-j9kg00qf 160 4 resulting result VBG cord-022526-j9kg00qf 160 5 from from IN cord-022526-j9kg00qf 160 6 vascular vascular JJ cord-022526-j9kg00qf 160 7 congestion congestion NN cord-022526-j9kg00qf 160 8 and and CC cord-022526-j9kg00qf 160 9 increased increase VBN cord-022526-j9kg00qf 160 10 endothelial endothelial JJ cord-022526-j9kg00qf 160 11 permeability permeability NN cord-022526-j9kg00qf 160 12 allows allow VBZ cord-022526-j9kg00qf 160 13 small small JJ cord-022526-j9kg00qf 160 14 macromolecules macromolecule NNS cord-022526-j9kg00qf 160 15 ( ( -LRB- cord-022526-j9kg00qf 160 16 albumin albumin NN cord-022526-j9kg00qf 160 17 ) ) -RRB- cord-022526-j9kg00qf 160 18 to to TO cord-022526-j9kg00qf 160 19 escape escape VB cord-022526-j9kg00qf 160 20 into into IN cord-022526-j9kg00qf 160 21 the the DT cord-022526-j9kg00qf 160 22 PF pf NN cord-022526-j9kg00qf 160 23 , , , cord-022526-j9kg00qf 160 24 followed follow VBN cord-022526-j9kg00qf 160 25 by by IN cord-022526-j9kg00qf 160 26 larger large JJR cord-022526-j9kg00qf 160 27 macromolecules macromolecule NNS cord-022526-j9kg00qf 160 28 ( ( -LRB- cord-022526-j9kg00qf 160 29 globulin globulin NN cord-022526-j9kg00qf 160 30 and and CC cord-022526-j9kg00qf 160 31 fibrinogen fibrinogen NN cord-022526-j9kg00qf 160 32 ) ) -RRB- cord-022526-j9kg00qf 160 33 , , , cord-022526-j9kg00qf 160 34 and and CC cord-022526-j9kg00qf 160 35 finally finally RB cord-022526-j9kg00qf 160 36 diapedesis diapedesis NNP cord-022526-j9kg00qf 160 37 of of IN cord-022526-j9kg00qf 160 38 cells cell NNS cord-022526-j9kg00qf 160 39 ( ( -LRB- cord-022526-j9kg00qf 160 40 red red JJ cord-022526-j9kg00qf 160 41 blood blood NN cord-022526-j9kg00qf 160 42 cells cell NNS cord-022526-j9kg00qf 160 43 , , , cord-022526-j9kg00qf 160 44 then then RB cord-022526-j9kg00qf 160 45 white white JJ cord-022526-j9kg00qf 160 46 blood blood NN cord-022526-j9kg00qf 160 47 cells cell NNS cord-022526-j9kg00qf 160 48 ) ) -RRB- cord-022526-j9kg00qf 160 49 . . . cord-022526-j9kg00qf 161 1 23 23 CD cord-022526-j9kg00qf 161 2 , , , cord-022526-j9kg00qf 161 3 24 24 CD cord-022526-j9kg00qf 162 1 If if IN cord-022526-j9kg00qf 162 2 ischemic ischemic JJ cord-022526-j9kg00qf 162 3 inflammation inflammation NN cord-022526-j9kg00qf 162 4 of of IN cord-022526-j9kg00qf 162 5 the the DT cord-022526-j9kg00qf 162 6 intestine intestine NN cord-022526-j9kg00qf 162 7 and and CC cord-022526-j9kg00qf 162 8 visceral visceral JJ cord-022526-j9kg00qf 162 9 peritonitis peritonitis NN cord-022526-j9kg00qf 162 10 occur occur VBP cord-022526-j9kg00qf 162 11 , , , cord-022526-j9kg00qf 162 12 an an DT cord-022526-j9kg00qf 162 13 exudative exudative JJ cord-022526-j9kg00qf 162 14 process process NN cord-022526-j9kg00qf 162 15 ensues ensue VBZ cord-022526-j9kg00qf 162 16 . . . cord-022526-j9kg00qf 163 1 Severe severe JJ cord-022526-j9kg00qf 163 2 inflammation inflammation NN cord-022526-j9kg00qf 163 3 of of IN cord-022526-j9kg00qf 163 4 the the DT cord-022526-j9kg00qf 163 5 intestine intestine NN cord-022526-j9kg00qf 163 6 and and CC cord-022526-j9kg00qf 163 7 visceral visceral JJ cord-022526-j9kg00qf 163 8 peritoneum peritoneum NN cord-022526-j9kg00qf 163 9 causes cause VBZ cord-022526-j9kg00qf 163 10 large large JJ cord-022526-j9kg00qf 163 11 quantities quantity NNS cord-022526-j9kg00qf 163 12 of of IN cord-022526-j9kg00qf 163 13 protein protein NN cord-022526-j9kg00qf 163 14 and and CC cord-022526-j9kg00qf 163 15 white white JJ cord-022526-j9kg00qf 163 16 blood blood NN cord-022526-j9kg00qf 163 17 cells cell NNS cord-022526-j9kg00qf 163 18 , , , cord-022526-j9kg00qf 163 19 primarily primarily RB cord-022526-j9kg00qf 163 20 neutrophils neutrophil NNS cord-022526-j9kg00qf 163 21 , , , cord-022526-j9kg00qf 163 22 to to TO cord-022526-j9kg00qf 163 23 escape escape VB cord-022526-j9kg00qf 163 24 into into IN cord-022526-j9kg00qf 163 25 the the DT cord-022526-j9kg00qf 163 26 PF pf NN cord-022526-j9kg00qf 163 27 . . . cord-022526-j9kg00qf 164 1 24 24 CD cord-022526-j9kg00qf 165 1 As as IN cord-022526-j9kg00qf 165 2 damage damage NN cord-022526-j9kg00qf 165 3 to to IN cord-022526-j9kg00qf 165 4 the the DT cord-022526-j9kg00qf 165 5 bowel bowel NN cord-022526-j9kg00qf 165 6 progresses progress VBZ cord-022526-j9kg00qf 165 7 , , , cord-022526-j9kg00qf 165 8 the the DT cord-022526-j9kg00qf 165 9 protein protein NN cord-022526-j9kg00qf 165 10 concentration concentration NN cord-022526-j9kg00qf 165 11 and and CC cord-022526-j9kg00qf 165 12 red red JJ cord-022526-j9kg00qf 165 13 blood blood NN cord-022526-j9kg00qf 165 14 cell cell NN cord-022526-j9kg00qf 165 15 and and CC cord-022526-j9kg00qf 165 16 white white JJ cord-022526-j9kg00qf 165 17 blood blood NN cord-022526-j9kg00qf 165 18 cell cell NN cord-022526-j9kg00qf 165 19 counts count NNS cord-022526-j9kg00qf 165 20 continue continue VBP cord-022526-j9kg00qf 165 21 to to TO cord-022526-j9kg00qf 165 22 rise rise VB cord-022526-j9kg00qf 165 23 . . . cord-022526-j9kg00qf 166 1 As as IN cord-022526-j9kg00qf 166 2 the the DT cord-022526-j9kg00qf 166 3 degree degree NN cord-022526-j9kg00qf 166 4 of of IN cord-022526-j9kg00qf 166 5 irreversible irreversible JJ cord-022526-j9kg00qf 166 6 damage damage NN cord-022526-j9kg00qf 166 7 to to IN cord-022526-j9kg00qf 166 8 the the DT cord-022526-j9kg00qf 166 9 intestine intestine NN cord-022526-j9kg00qf 166 10 increases increase NNS cord-022526-j9kg00qf 166 11 , , , cord-022526-j9kg00qf 166 12 the the DT cord-022526-j9kg00qf 166 13 PF PF NNP cord-022526-j9kg00qf 166 14 characteristics characteristic NNS cord-022526-j9kg00qf 166 15 become become VBP cord-022526-j9kg00qf 166 16 more more RBR cord-022526-j9kg00qf 166 17 exudative exudative JJ cord-022526-j9kg00qf 166 18 . . . cord-022526-j9kg00qf 167 1 23 23 CD cord-022526-j9kg00qf 167 2 , , , cord-022526-j9kg00qf 167 3 24 24 CD cord-022526-j9kg00qf 167 4 Eventually eventually RB cord-022526-j9kg00qf 167 5 , , , cord-022526-j9kg00qf 167 6 bacteria bacteria NNS cord-022526-j9kg00qf 167 7 begin begin VBP cord-022526-j9kg00qf 167 8 to to TO cord-022526-j9kg00qf 167 9 translocate translocate VB cord-022526-j9kg00qf 167 10 across across IN cord-022526-j9kg00qf 167 11 the the DT cord-022526-j9kg00qf 167 12 intestinal intestinal JJ cord-022526-j9kg00qf 167 13 wall wall NN cord-022526-j9kg00qf 167 14 and and CC cord-022526-j9kg00qf 167 15 appear appear VB cord-022526-j9kg00qf 167 16 in in IN cord-022526-j9kg00qf 167 17 the the DT cord-022526-j9kg00qf 167 18 PF PF NNP cord-022526-j9kg00qf 167 19 as as IN cord-022526-j9kg00qf 167 20 the the DT cord-022526-j9kg00qf 167 21 mucosal mucosal JJ cord-022526-j9kg00qf 167 22 barrier barrier NN cord-022526-j9kg00qf 167 23 breaks break VBZ cord-022526-j9kg00qf 167 24 down down RP cord-022526-j9kg00qf 167 25 . . . cord-022526-j9kg00qf 168 1 Neutrophils neutrophils NN cord-022526-j9kg00qf 168 2 predominate predominate VBP cord-022526-j9kg00qf 168 3 , , , cord-022526-j9kg00qf 168 4 and and CC cord-022526-j9kg00qf 168 5 their -PRON- PRP$ cord-022526-j9kg00qf 168 6 cytoplasm cytoplasm NN cord-022526-j9kg00qf 168 7 becomes become VBZ cord-022526-j9kg00qf 168 8 granulated granulated JJ cord-022526-j9kg00qf 168 9 , , , cord-022526-j9kg00qf 168 10 and and CC cord-022526-j9kg00qf 168 11 Döhle Döhle NNP cord-022526-j9kg00qf 168 12 bodies body NNS cord-022526-j9kg00qf 168 13 often often RB cord-022526-j9kg00qf 168 14 are be VBP cord-022526-j9kg00qf 168 15 visible visible JJ cord-022526-j9kg00qf 168 16 . . . cord-022526-j9kg00qf 169 1 If if IN cord-022526-j9kg00qf 169 2 perforation perforation NN cord-022526-j9kg00qf 169 3 occurs occur VBZ cord-022526-j9kg00qf 169 4 , , , cord-022526-j9kg00qf 169 5 bacteria bacteria NNS cord-022526-j9kg00qf 169 6 and and CC cord-022526-j9kg00qf 169 7 particles particle NNS cord-022526-j9kg00qf 169 8 of of IN cord-022526-j9kg00qf 169 9 ingesta ingesta NNS cord-022526-j9kg00qf 169 10 appear appear VBP cord-022526-j9kg00qf 169 11 in in IN cord-022526-j9kg00qf 169 12 the the DT cord-022526-j9kg00qf 169 13 PF pf NN cord-022526-j9kg00qf 169 14 , , , cord-022526-j9kg00qf 169 15 and and CC cord-022526-j9kg00qf 169 16 the the DT cord-022526-j9kg00qf 169 17 neutrophils neutrophil NNS cord-022526-j9kg00qf 169 18 become become VBP cord-022526-j9kg00qf 169 19 degenerate degenerate JJ cord-022526-j9kg00qf 169 20 , , , cord-022526-j9kg00qf 169 21 that that RB cord-022526-j9kg00qf 169 22 is is RB cord-022526-j9kg00qf 169 23 , , , cord-022526-j9kg00qf 169 24 pyknotic pyknotic JJ cord-022526-j9kg00qf 169 25 , , , cord-022526-j9kg00qf 169 26 with with IN cord-022526-j9kg00qf 169 27 karyorrhexis karyorrhexis NNP cord-022526-j9kg00qf 169 28 , , , cord-022526-j9kg00qf 169 29 karyolysis karyolysis NNP cord-022526-j9kg00qf 169 30 , , , cord-022526-j9kg00qf 169 31 and and CC cord-022526-j9kg00qf 169 32 smudge smudge VB cord-022526-j9kg00qf 169 33 cells cell NNS cord-022526-j9kg00qf 169 34 . . . cord-022526-j9kg00qf 170 1 23 23 CD cord-022526-j9kg00qf 170 2 Elevated elevated JJ cord-022526-j9kg00qf 170 3 PF PF NNP cord-022526-j9kg00qf 170 4 protein protein NN cord-022526-j9kg00qf 170 5 concentration concentration NN cord-022526-j9kg00qf 170 6 is be VBZ cord-022526-j9kg00qf 170 7 a a DT cord-022526-j9kg00qf 170 8 sensitive sensitive JJ cord-022526-j9kg00qf 170 9 indicator indicator NN cord-022526-j9kg00qf 170 10 of of IN cord-022526-j9kg00qf 170 11 early early JJ cord-022526-j9kg00qf 170 12 inflammation inflammation NN cord-022526-j9kg00qf 170 13 , , , cord-022526-j9kg00qf 170 14 whereas whereas IN cord-022526-j9kg00qf 170 15 elevated elevated JJ cord-022526-j9kg00qf 170 16 red red JJ cord-022526-j9kg00qf 170 17 blood blood NN cord-022526-j9kg00qf 170 18 cell cell NN cord-022526-j9kg00qf 170 19 counts count VBZ cord-022526-j9kg00qf 170 20 in in IN cord-022526-j9kg00qf 170 21 the the DT cord-022526-j9kg00qf 170 22 presence presence NN cord-022526-j9kg00qf 170 23 of of IN cord-022526-j9kg00qf 170 24 normal normal JJ cord-022526-j9kg00qf 170 25 white white JJ cord-022526-j9kg00qf 170 26 blood blood NN cord-022526-j9kg00qf 170 27 cell cell NN cord-022526-j9kg00qf 170 28 counts count NNS cord-022526-j9kg00qf 170 29 suggest suggest VBP cord-022526-j9kg00qf 170 30 vascular vascular JJ cord-022526-j9kg00qf 170 31 damage damage NN cord-022526-j9kg00qf 170 32 without without IN cord-022526-j9kg00qf 170 33 significant significant JJ cord-022526-j9kg00qf 170 34 tissue tissue NN cord-022526-j9kg00qf 170 35 ischemia ischemia NN cord-022526-j9kg00qf 170 36 . . . cord-022526-j9kg00qf 171 1 24 24 CD cord-022526-j9kg00qf 171 2 Elevation elevation NN cord-022526-j9kg00qf 171 3 of of IN cord-022526-j9kg00qf 171 4 the the DT cord-022526-j9kg00qf 171 5 white white JJ cord-022526-j9kg00qf 171 6 blood blood NN cord-022526-j9kg00qf 171 7 cell cell NN cord-022526-j9kg00qf 171 8 count count NN cord-022526-j9kg00qf 171 9 usually usually RB cord-022526-j9kg00qf 171 10 indicates indicate VBZ cord-022526-j9kg00qf 171 11 severe severe JJ cord-022526-j9kg00qf 171 12 tissue tissue NN cord-022526-j9kg00qf 171 13 inflammation inflammation NN cord-022526-j9kg00qf 171 14 or or CC cord-022526-j9kg00qf 171 15 intestinal intestinal JJ cord-022526-j9kg00qf 171 16 injury injury NN cord-022526-j9kg00qf 171 17 . . . cord-022526-j9kg00qf 172 1 25 25 CD cord-022526-j9kg00qf 173 1 The the DT cord-022526-j9kg00qf 173 2 gross gross JJ cord-022526-j9kg00qf 173 3 color color NN cord-022526-j9kg00qf 173 4 of of IN cord-022526-j9kg00qf 173 5 the the DT cord-022526-j9kg00qf 173 6 PF pf NN cord-022526-j9kg00qf 173 7 can can MD cord-022526-j9kg00qf 173 8 be be VB cord-022526-j9kg00qf 173 9 helpful helpful JJ cord-022526-j9kg00qf 173 10 in in IN cord-022526-j9kg00qf 173 11 detecting detect VBG cord-022526-j9kg00qf 173 12 injury injury NN cord-022526-j9kg00qf 173 13 and and CC cord-022526-j9kg00qf 173 14 necrosis necrosis NN cord-022526-j9kg00qf 173 15 of of IN cord-022526-j9kg00qf 173 16 the the DT cord-022526-j9kg00qf 173 17 intestine intestine NN cord-022526-j9kg00qf 173 18 . . . cord-022526-j9kg00qf 174 1 A a DT cord-022526-j9kg00qf 174 2 serosanguinous serosanguinous JJ cord-022526-j9kg00qf 174 3 appearance appearance NN cord-022526-j9kg00qf 174 4 indicates indicate VBZ cord-022526-j9kg00qf 174 5 vascular vascular JJ cord-022526-j9kg00qf 174 6 injury injury NN cord-022526-j9kg00qf 174 7 , , , cord-022526-j9kg00qf 174 8 whereas whereas IN cord-022526-j9kg00qf 174 9 orange orange JJ cord-022526-j9kg00qf 174 10 or or CC cord-022526-j9kg00qf 174 11 brown brown JJ cord-022526-j9kg00qf 174 12 - - HYPH cord-022526-j9kg00qf 174 13 red red NN cord-022526-j9kg00qf 174 14 indicates indicate VBZ cord-022526-j9kg00qf 174 15 necrosis necrosis NN cord-022526-j9kg00qf 174 16 with with IN cord-022526-j9kg00qf 174 17 the the DT cord-022526-j9kg00qf 174 18 release release NN cord-022526-j9kg00qf 174 19 of of IN cord-022526-j9kg00qf 174 20 pigments pigment NNS cord-022526-j9kg00qf 174 21 such such JJ cord-022526-j9kg00qf 174 22 as as IN cord-022526-j9kg00qf 174 23 hemosiderin hemosiderin NNP cord-022526-j9kg00qf 174 24 . . . cord-022526-j9kg00qf 175 1 Serial serial JJ cord-022526-j9kg00qf 175 2 samples sample NNS cord-022526-j9kg00qf 175 3 of of IN cord-022526-j9kg00qf 175 4 PF pf NN cord-022526-j9kg00qf 175 5 are be VBP cord-022526-j9kg00qf 175 6 most most RBS cord-022526-j9kg00qf 175 7 useful useful JJ cord-022526-j9kg00qf 175 8 in in IN cord-022526-j9kg00qf 175 9 determining determine VBG cord-022526-j9kg00qf 175 10 the the DT cord-022526-j9kg00qf 175 11 nature nature NN cord-022526-j9kg00qf 175 12 and and CC cord-022526-j9kg00qf 175 13 extent extent NN cord-022526-j9kg00qf 175 14 of of IN cord-022526-j9kg00qf 175 15 damage damage NN cord-022526-j9kg00qf 175 16 to to IN cord-022526-j9kg00qf 175 17 the the DT cord-022526-j9kg00qf 175 18 intestine intestine NN cord-022526-j9kg00qf 175 19 , , , cord-022526-j9kg00qf 175 20 but but CC cord-022526-j9kg00qf 175 21 in in IN cord-022526-j9kg00qf 175 22 many many JJ cord-022526-j9kg00qf 175 23 cases case NNS cord-022526-j9kg00qf 175 24 of of IN cord-022526-j9kg00qf 175 25 ischemia ischemia NN cord-022526-j9kg00qf 175 26 , , , cord-022526-j9kg00qf 175 27 irreversible irreversible JJ cord-022526-j9kg00qf 175 28 tissue tissue NN cord-022526-j9kg00qf 175 29 damage damage NN cord-022526-j9kg00qf 175 30 has have VBZ cord-022526-j9kg00qf 175 31 occurred occur VBN cord-022526-j9kg00qf 175 32 by by IN cord-022526-j9kg00qf 175 33 the the DT cord-022526-j9kg00qf 175 34 time time NN cord-022526-j9kg00qf 175 35 PF PF NNP cord-022526-j9kg00qf 175 36 abnormalities abnormality NNS cord-022526-j9kg00qf 175 37 appear appear VBP cord-022526-j9kg00qf 175 38 . . . cord-022526-j9kg00qf 176 1 Tissue tissue NN cord-022526-j9kg00qf 176 2 hypoxia hypoxia NN cord-022526-j9kg00qf 176 3 and and CC cord-022526-j9kg00qf 176 4 ischemia ischemia NN cord-022526-j9kg00qf 176 5 cause cause VBP cord-022526-j9kg00qf 176 6 a a DT cord-022526-j9kg00qf 176 7 rapid rapid JJ cord-022526-j9kg00qf 176 8 elevation elevation NN cord-022526-j9kg00qf 176 9 of of IN cord-022526-j9kg00qf 176 10 PF pf NN cord-022526-j9kg00qf 176 11 lactate lactate NN cord-022526-j9kg00qf 176 12 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 176 13 , , , cord-022526-j9kg00qf 176 14 creatine creatine NN cord-022526-j9kg00qf 176 15 kinase kinase NN cord-022526-j9kg00qf 176 16 , , , cord-022526-j9kg00qf 176 17 and and CC cord-022526-j9kg00qf 176 18 alkaline alkaline JJ cord-022526-j9kg00qf 176 19 phosphatase phosphatase NN cord-022526-j9kg00qf 176 20 activity activity NN cord-022526-j9kg00qf 176 21 and and CC cord-022526-j9kg00qf 176 22 lactate lactate NN cord-022526-j9kg00qf 176 23 concentration concentration NN cord-022526-j9kg00qf 176 24 . . . cord-022526-j9kg00qf 177 1 19 19 CD cord-022526-j9kg00qf 177 2 , , , cord-022526-j9kg00qf 177 3 20 20 CD cord-022526-j9kg00qf 177 4 , , , cord-022526-j9kg00qf 177 5 26 26 CD cord-022526-j9kg00qf 177 6 Phosphate phosphate NN cord-022526-j9kg00qf 177 7 concentration concentration NN cord-022526-j9kg00qf 177 8 increases increase VBZ cord-022526-j9kg00qf 177 9 when when WRB cord-022526-j9kg00qf 177 10 cellular cellular JJ cord-022526-j9kg00qf 177 11 disruption disruption NN cord-022526-j9kg00qf 177 12 occurs occur VBZ cord-022526-j9kg00qf 177 13 . . . cord-022526-j9kg00qf 178 1 18 18 CD cord-022526-j9kg00qf 178 2 PF pf NN cord-022526-j9kg00qf 178 3 enzyme enzyme NN cord-022526-j9kg00qf 178 4 activities activity NNS cord-022526-j9kg00qf 178 5 , , , cord-022526-j9kg00qf 178 6 phosphate phosphate NN cord-022526-j9kg00qf 178 7 , , , cord-022526-j9kg00qf 178 8 and and CC cord-022526-j9kg00qf 178 9 lactate lactate NN cord-022526-j9kg00qf 178 10 concentration concentration NN cord-022526-j9kg00qf 178 11 increase increase VBP cord-022526-j9kg00qf 178 12 faster fast RBR cord-022526-j9kg00qf 178 13 and and CC cord-022526-j9kg00qf 178 14 higher high JJR cord-022526-j9kg00qf 178 15 than than IN cord-022526-j9kg00qf 178 16 serum serum NN cord-022526-j9kg00qf 178 17 activities activity NNS cord-022526-j9kg00qf 178 18 . . . cord-022526-j9kg00qf 179 1 [ [ -LRB- cord-022526-j9kg00qf 179 2 18 18 CD cord-022526-j9kg00qf 179 3 ] ] -RRB- cord-022526-j9kg00qf 179 4 [ [ -LRB- cord-022526-j9kg00qf 179 5 19 19 CD cord-022526-j9kg00qf 179 6 ] ] -RRB- cord-022526-j9kg00qf 179 7 [ [ -LRB- cord-022526-j9kg00qf 179 8 20 20 CD cord-022526-j9kg00qf 179 9 ] ] -RRB- cord-022526-j9kg00qf 179 10 26 26 CD cord-022526-j9kg00qf 179 11 PF pf NN cord-022526-j9kg00qf 179 12 pH ph NN cord-022526-j9kg00qf 179 13 and and CC cord-022526-j9kg00qf 179 14 glucose glucose NN cord-022526-j9kg00qf 179 15 concentration concentration NN cord-022526-j9kg00qf 179 16 tend tend VBP cord-022526-j9kg00qf 179 17 to to TO cord-022526-j9kg00qf 179 18 decrease decrease VB cord-022526-j9kg00qf 179 19 during during IN cord-022526-j9kg00qf 179 20 intestinal intestinal JJ cord-022526-j9kg00qf 179 21 ischemia ischemia NN cord-022526-j9kg00qf 179 22 , , , cord-022526-j9kg00qf 179 23 but but CC cord-022526-j9kg00qf 179 24 not not RB cord-022526-j9kg00qf 179 25 as as RB cord-022526-j9kg00qf 179 26 low low JJ cord-022526-j9kg00qf 179 27 as as IN cord-022526-j9kg00qf 179 28 in in IN cord-022526-j9kg00qf 179 29 septic septic JJ cord-022526-j9kg00qf 179 30 peritonitis peritonitis NN cord-022526-j9kg00qf 179 31 . . . cord-022526-j9kg00qf 180 1 27 27 CD cord-022526-j9kg00qf 181 1 Although although IN cord-022526-j9kg00qf 181 2 biochemical biochemical JJ cord-022526-j9kg00qf 181 3 alterations alteration NNS cord-022526-j9kg00qf 181 4 may may MD cord-022526-j9kg00qf 181 5 provide provide VB cord-022526-j9kg00qf 181 6 early early JJ cord-022526-j9kg00qf 181 7 indicators indicator NNS cord-022526-j9kg00qf 181 8 of of IN cord-022526-j9kg00qf 181 9 intestinal intestinal JJ cord-022526-j9kg00qf 181 10 ischemia ischemia NN cord-022526-j9kg00qf 181 11 and and CC cord-022526-j9kg00qf 181 12 necrosis necrosis NN cord-022526-j9kg00qf 181 13 , , , cord-022526-j9kg00qf 181 14 they -PRON- PRP cord-022526-j9kg00qf 181 15 are be VBP cord-022526-j9kg00qf 181 16 nonspecific nonspecific JJ cord-022526-j9kg00qf 181 17 and and CC cord-022526-j9kg00qf 181 18 offer offer VBP cord-022526-j9kg00qf 181 19 no no DT cord-022526-j9kg00qf 181 20 advantage advantage NN cord-022526-j9kg00qf 181 21 over over IN cord-022526-j9kg00qf 181 22 conventional conventional JJ cord-022526-j9kg00qf 181 23 methods method NNS cord-022526-j9kg00qf 181 24 of of IN cord-022526-j9kg00qf 181 25 PF pf NN cord-022526-j9kg00qf 181 26 analysis analysis NN cord-022526-j9kg00qf 181 27 in in IN cord-022526-j9kg00qf 181 28 many many JJ cord-022526-j9kg00qf 181 29 cases case NNS cord-022526-j9kg00qf 181 30 . . . cord-022526-j9kg00qf 182 1 PF PF NNP cord-022526-j9kg00qf 182 2 alkaline alkaline JJ cord-022526-j9kg00qf 182 3 phosphatase phosphatase NN cord-022526-j9kg00qf 182 4 has have VBZ cord-022526-j9kg00qf 182 5 been be VBN cord-022526-j9kg00qf 182 6 shown show VBN cord-022526-j9kg00qf 182 7 to to TO cord-022526-j9kg00qf 182 8 arise arise VB cord-022526-j9kg00qf 182 9 predominantly predominantly RB cord-022526-j9kg00qf 182 10 from from IN cord-022526-j9kg00qf 182 11 degenerating degenerate VBG cord-022526-j9kg00qf 182 12 white white JJ cord-022526-j9kg00qf 182 13 blood blood NN cord-022526-j9kg00qf 182 14 cells cell NNS cord-022526-j9kg00qf 182 15 , , , cord-022526-j9kg00qf 182 16 and and CC cord-022526-j9kg00qf 182 17 elevations elevation NNS cord-022526-j9kg00qf 182 18 of of IN cord-022526-j9kg00qf 182 19 other other JJ cord-022526-j9kg00qf 182 20 enzyme enzyme NN cord-022526-j9kg00qf 182 21 activities activity NNS cord-022526-j9kg00qf 182 22 may may MD cord-022526-j9kg00qf 182 23 occur occur VB cord-022526-j9kg00qf 182 24 with with IN cord-022526-j9kg00qf 182 25 many many JJ cord-022526-j9kg00qf 182 26 inflammatory inflammatory JJ cord-022526-j9kg00qf 182 27 diseases disease NNS cord-022526-j9kg00qf 182 28 . . . cord-022526-j9kg00qf 183 1 26 26 CD cord-022526-j9kg00qf 184 1 Thus thus RB cord-022526-j9kg00qf 184 2 the the DT cord-022526-j9kg00qf 184 3 specificity specificity NN cord-022526-j9kg00qf 184 4 of of IN cord-022526-j9kg00qf 184 5 many many JJ cord-022526-j9kg00qf 184 6 tests test NNS cord-022526-j9kg00qf 184 7 run run VBP cord-022526-j9kg00qf 184 8 on on IN cord-022526-j9kg00qf 184 9 PF PF NNP cord-022526-j9kg00qf 184 10 is be VBZ cord-022526-j9kg00qf 184 11 questionable questionable JJ cord-022526-j9kg00qf 184 12 . . . cord-022526-j9kg00qf 185 1 However however RB cord-022526-j9kg00qf 185 2 , , , cord-022526-j9kg00qf 185 3 in in IN cord-022526-j9kg00qf 185 4 selected select VBN cord-022526-j9kg00qf 185 5 cases case NNS cord-022526-j9kg00qf 185 6 in in IN cord-022526-j9kg00qf 185 7 which which WDT cord-022526-j9kg00qf 185 8 conventional conventional JJ cord-022526-j9kg00qf 185 9 PF pf NN cord-022526-j9kg00qf 185 10 analysis analysis NN cord-022526-j9kg00qf 185 11 and and CC cord-022526-j9kg00qf 185 12 physical physical JJ cord-022526-j9kg00qf 185 13 examination examination NN cord-022526-j9kg00qf 185 14 do do VBP cord-022526-j9kg00qf 185 15 not not RB cord-022526-j9kg00qf 185 16 provide provide VB cord-022526-j9kg00qf 185 17 sufficient sufficient JJ cord-022526-j9kg00qf 185 18 information information NN cord-022526-j9kg00qf 185 19 to to TO cord-022526-j9kg00qf 185 20 develop develop VB cord-022526-j9kg00qf 185 21 a a DT cord-022526-j9kg00qf 185 22 treatment treatment NN cord-022526-j9kg00qf 185 23 plan plan NN cord-022526-j9kg00qf 185 24 , , , cord-022526-j9kg00qf 185 25 biochemical biochemical JJ cord-022526-j9kg00qf 185 26 analysis analysis NN cord-022526-j9kg00qf 185 27 of of IN cord-022526-j9kg00qf 185 28 the the DT cord-022526-j9kg00qf 185 29 PF PF NNP cord-022526-j9kg00qf 185 30 may may MD cord-022526-j9kg00qf 185 31 be be VB cord-022526-j9kg00qf 185 32 useful useful JJ cord-022526-j9kg00qf 185 33 . . . cord-022526-j9kg00qf 186 1 Cytologically Cytologically NNP cord-022526-j9kg00qf 186 2 examined examine VBD cord-022526-j9kg00qf 186 3 cells cell NNS cord-022526-j9kg00qf 186 4 of of IN cord-022526-j9kg00qf 186 5 the the DT cord-022526-j9kg00qf 186 6 PF PF NNP cord-022526-j9kg00qf 186 7 may may MD cord-022526-j9kg00qf 186 8 reflect reflect VB cord-022526-j9kg00qf 186 9 chronic chronic JJ cord-022526-j9kg00qf 186 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 186 11 conditions condition NNS cord-022526-j9kg00qf 186 12 of of IN cord-022526-j9kg00qf 186 13 the the DT cord-022526-j9kg00qf 186 14 large large JJ cord-022526-j9kg00qf 186 15 intestine intestine NN cord-022526-j9kg00qf 186 16 , , , cord-022526-j9kg00qf 186 17 especially especially RB cord-022526-j9kg00qf 186 18 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 186 19 or or CC cord-022526-j9kg00qf 186 20 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 186 21 processes process NNS cord-022526-j9kg00qf 186 22 . . . cord-022526-j9kg00qf 187 1 28 28 CD cord-022526-j9kg00qf 187 2 Infectious infectious JJ cord-022526-j9kg00qf 187 3 and and CC cord-022526-j9kg00qf 187 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 187 5 conditions condition NNS cord-022526-j9kg00qf 187 6 often often RB cord-022526-j9kg00qf 187 7 cause cause VBP cord-022526-j9kg00qf 187 8 increases increase NNS cord-022526-j9kg00qf 187 9 in in IN cord-022526-j9kg00qf 187 10 the the DT cord-022526-j9kg00qf 187 11 neutrophil neutrophil NN cord-022526-j9kg00qf 187 12 count count NN cord-022526-j9kg00qf 187 13 and and CC cord-022526-j9kg00qf 187 14 may may MD cord-022526-j9kg00qf 187 15 be be VB cord-022526-j9kg00qf 187 16 indistinguishable indistinguishable JJ cord-022526-j9kg00qf 187 17 unless unless IN cord-022526-j9kg00qf 187 18 bacteria bacteria NNS cord-022526-j9kg00qf 187 19 are be VBP cord-022526-j9kg00qf 187 20 visible visible JJ cord-022526-j9kg00qf 187 21 . . . cord-022526-j9kg00qf 188 1 One one CD cord-022526-j9kg00qf 188 2 also also RB cord-022526-j9kg00qf 188 3 may may MD cord-022526-j9kg00qf 188 4 detect detect VB cord-022526-j9kg00qf 188 5 neoplastic neoplastic JJ cord-022526-j9kg00qf 188 6 diseases disease NNS cord-022526-j9kg00qf 188 7 by by IN cord-022526-j9kg00qf 188 8 PF pf NN cord-022526-j9kg00qf 188 9 examination examination NN cord-022526-j9kg00qf 188 10 . . . cord-022526-j9kg00qf 189 1 Chronic chronic JJ cord-022526-j9kg00qf 189 2 infection infection NN cord-022526-j9kg00qf 189 3 and and CC cord-022526-j9kg00qf 189 4 inflammation inflammation NN cord-022526-j9kg00qf 189 5 may may MD cord-022526-j9kg00qf 189 6 be be VB cord-022526-j9kg00qf 189 7 associated associate VBN cord-022526-j9kg00qf 189 8 with with IN cord-022526-j9kg00qf 189 9 elevated elevated JJ cord-022526-j9kg00qf 189 10 PF pf NN cord-022526-j9kg00qf 189 11 protein protein NN cord-022526-j9kg00qf 189 12 and and CC cord-022526-j9kg00qf 189 13 fibrinogen fibrinogen NN cord-022526-j9kg00qf 189 14 concentrations concentration NNS cord-022526-j9kg00qf 189 15 . . . cord-022526-j9kg00qf 190 1 Culture culture NN cord-022526-j9kg00qf 190 2 of of IN cord-022526-j9kg00qf 190 3 PF pf NN cord-022526-j9kg00qf 190 4 usually usually RB cord-022526-j9kg00qf 190 5 is be VBZ cord-022526-j9kg00qf 190 6 required require VBN cord-022526-j9kg00qf 190 7 to to TO cord-022526-j9kg00qf 190 8 distinguish distinguish VB cord-022526-j9kg00qf 190 9 bacterial bacterial JJ cord-022526-j9kg00qf 190 10 infections infection NNS cord-022526-j9kg00qf 190 11 from from IN cord-022526-j9kg00qf 190 12 noninfectious noninfectious JJ cord-022526-j9kg00qf 190 13 inflammation inflammation NN cord-022526-j9kg00qf 190 14 unless unless IN cord-022526-j9kg00qf 190 15 bacteria bacteria NNS cord-022526-j9kg00qf 190 16 are be VBP cord-022526-j9kg00qf 190 17 visible visible JJ cord-022526-j9kg00qf 190 18 on on IN cord-022526-j9kg00qf 190 19 cytologic cytologic JJ cord-022526-j9kg00qf 190 20 examination examination NN cord-022526-j9kg00qf 190 21 . . . cord-022526-j9kg00qf 191 1 However however RB cord-022526-j9kg00qf 191 2 , , , cord-022526-j9kg00qf 191 3 culture culture NN cord-022526-j9kg00qf 191 4 of of IN cord-022526-j9kg00qf 191 5 PF pf NN cord-022526-j9kg00qf 191 6 is be VBZ cord-022526-j9kg00qf 191 7 often often RB cord-022526-j9kg00qf 191 8 unrewarding unrewarding JJ cord-022526-j9kg00qf 191 9 because because IN cord-022526-j9kg00qf 191 10 factors factor NNS cord-022526-j9kg00qf 191 11 that that WDT cord-022526-j9kg00qf 191 12 are be VBP cord-022526-j9kg00qf 191 13 found find VBN cord-022526-j9kg00qf 191 14 in in IN cord-022526-j9kg00qf 191 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 191 16 PF pf NN cord-022526-j9kg00qf 191 17 inhibit inhibit VBP cord-022526-j9kg00qf 191 18 bacterial bacterial JJ cord-022526-j9kg00qf 191 19 growth growth NN cord-022526-j9kg00qf 191 20 , , , cord-022526-j9kg00qf 191 21 and and CC cord-022526-j9kg00qf 191 22 leukocytes leukocyte NNS cord-022526-j9kg00qf 191 23 phagocytose phagocytose VBD cord-022526-j9kg00qf 191 24 many many JJ cord-022526-j9kg00qf 191 25 bacteria bacteria NNS cord-022526-j9kg00qf 191 26 in in IN cord-022526-j9kg00qf 191 27 the the DT cord-022526-j9kg00qf 191 28 PF pf NN cord-022526-j9kg00qf 191 29 . . . cord-022526-j9kg00qf 192 1 29 29 CD cord-022526-j9kg00qf 192 2 Decreases decrease NNS cord-022526-j9kg00qf 192 3 in in IN cord-022526-j9kg00qf 192 4 PF pf NN cord-022526-j9kg00qf 192 5 glucose glucose NN cord-022526-j9kg00qf 192 6 concentrations concentration NNS cord-022526-j9kg00qf 192 7 ( ( -LRB- cord-022526-j9kg00qf 192 8 < < NNP cord-022526-j9kg00qf 192 9 30 30 CD cord-022526-j9kg00qf 192 10 mg mg NNP cord-022526-j9kg00qf 192 11 / / SYM cord-022526-j9kg00qf 192 12 dl dl NNP cord-022526-j9kg00qf 192 13 ) ) -RRB- cord-022526-j9kg00qf 192 14 and and CC cord-022526-j9kg00qf 192 15 pH pH NNP cord-022526-j9kg00qf 192 16 ( ( -LRB- cord-022526-j9kg00qf 192 17 < < NNP cord-022526-j9kg00qf 192 18 7.3 7.3 CD cord-022526-j9kg00qf 192 19 ) ) -RRB- cord-022526-j9kg00qf 192 20 are be VBP cord-022526-j9kg00qf 192 21 early early JJ cord-022526-j9kg00qf 192 22 indicators indicator NNS cord-022526-j9kg00qf 192 23 of of IN cord-022526-j9kg00qf 192 24 a a DT cord-022526-j9kg00qf 192 25 septic septic JJ cord-022526-j9kg00qf 192 26 process process NN cord-022526-j9kg00qf 192 27 . . . cord-022526-j9kg00qf 193 1 The the DT cord-022526-j9kg00qf 193 2 glucose glucose NN cord-022526-j9kg00qf 193 3 concentration concentration NN cord-022526-j9kg00qf 193 4 and and CC cord-022526-j9kg00qf 193 5 pH ph NN cord-022526-j9kg00qf 193 6 in in IN cord-022526-j9kg00qf 193 7 the the DT cord-022526-j9kg00qf 193 8 PF pf NN cord-022526-j9kg00qf 193 9 should should MD cord-022526-j9kg00qf 193 10 approximately approximately RB cord-022526-j9kg00qf 193 11 equal equal VB cord-022526-j9kg00qf 193 12 the the DT cord-022526-j9kg00qf 193 13 blood blood NN cord-022526-j9kg00qf 193 14 glucose glucose NN cord-022526-j9kg00qf 193 15 concentration concentration NN cord-022526-j9kg00qf 193 16 and and CC cord-022526-j9kg00qf 193 17 pH. ph. NN cord-022526-j9kg00qf 193 18 A a DT cord-022526-j9kg00qf 193 19 PF PF NNP cord-022526-j9kg00qf 193 20 fibrinogen fibrinogen NN cord-022526-j9kg00qf 193 21 concentration concentration NN cord-022526-j9kg00qf 193 22 greater great JJR cord-022526-j9kg00qf 193 23 than than IN cord-022526-j9kg00qf 193 24 200 200 CD cord-022526-j9kg00qf 193 25 mg mg NNP cord-022526-j9kg00qf 193 26 / / SYM cord-022526-j9kg00qf 193 27 dl dl NNP cord-022526-j9kg00qf 193 28 also also RB cord-022526-j9kg00qf 193 29 indicates indicate VBZ cord-022526-j9kg00qf 193 30 bacterial bacterial JJ cord-022526-j9kg00qf 193 31 infection infection NN cord-022526-j9kg00qf 193 32 . . . cord-022526-j9kg00qf 194 1 30 30 CD cord-022526-j9kg00qf 194 2 _SP cord-022526-j9kg00qf 195 1 Gross gross JJ cord-022526-j9kg00qf 195 2 examination examination NN cord-022526-j9kg00qf 195 3 of of IN cord-022526-j9kg00qf 195 4 the the DT cord-022526-j9kg00qf 195 5 feces fece NNS cord-022526-j9kg00qf 195 6 can can MD cord-022526-j9kg00qf 195 7 provide provide VB cord-022526-j9kg00qf 195 8 information information NN cord-022526-j9kg00qf 195 9 about about IN cord-022526-j9kg00qf 195 10 digestion digestion NN cord-022526-j9kg00qf 195 11 and and CC cord-022526-j9kg00qf 195 12 transit transit NN cord-022526-j9kg00qf 195 13 time time NN cord-022526-j9kg00qf 195 14 in in IN cord-022526-j9kg00qf 195 15 the the DT cord-022526-j9kg00qf 195 16 large large JJ cord-022526-j9kg00qf 195 17 intestine intestine NN cord-022526-j9kg00qf 195 18 . . . cord-022526-j9kg00qf 196 1 Large large JJ cord-022526-j9kg00qf 196 2 fiber fiber NN cord-022526-j9kg00qf 196 3 particles particle NNS cord-022526-j9kg00qf 196 4 in in IN cord-022526-j9kg00qf 196 5 the the DT cord-022526-j9kg00qf 196 6 feces fece NNS cord-022526-j9kg00qf 196 7 represent represent VBP cord-022526-j9kg00qf 196 8 poor poor JJ cord-022526-j9kg00qf 196 9 mastication mastication NN cord-022526-j9kg00qf 196 10 or or CC cord-022526-j9kg00qf 196 11 poor poor JJ cord-022526-j9kg00qf 196 12 digestion digestion NN cord-022526-j9kg00qf 196 13 in in IN cord-022526-j9kg00qf 196 14 the the DT cord-022526-j9kg00qf 196 15 large large JJ cord-022526-j9kg00qf 196 16 intestine intestine NN cord-022526-j9kg00qf 196 17 . . . cord-022526-j9kg00qf 197 1 Small small JJ cord-022526-j9kg00qf 197 2 , , , cord-022526-j9kg00qf 197 3 mucuscovered mucuscovered JJ cord-022526-j9kg00qf 197 4 , , , cord-022526-j9kg00qf 197 5 hard hard JJ cord-022526-j9kg00qf 197 6 fecal fecal JJ cord-022526-j9kg00qf 197 7 balls ball NNS cord-022526-j9kg00qf 197 8 indicate indicate VBP cord-022526-j9kg00qf 197 9 prolonged prolong VBN cord-022526-j9kg00qf 197 10 transit transit NN cord-022526-j9kg00qf 197 11 through through IN cord-022526-j9kg00qf 197 12 the the DT cord-022526-j9kg00qf 197 13 descending descend VBG cord-022526-j9kg00qf 197 14 colon colon NN cord-022526-j9kg00qf 197 15 , , , cord-022526-j9kg00qf 197 16 whereas whereas IN cord-022526-j9kg00qf 197 17 increased increase VBN cord-022526-j9kg00qf 197 18 fluidity fluidity NN cord-022526-j9kg00qf 197 19 implies imply VBZ cord-022526-j9kg00qf 197 20 decreased decrease VBD cord-022526-j9kg00qf 197 21 transit transit NN cord-022526-j9kg00qf 197 22 time time NN cord-022526-j9kg00qf 197 23 . . . cord-022526-j9kg00qf 198 1 Feces fece NNS cord-022526-j9kg00qf 198 2 containing contain VBG cord-022526-j9kg00qf 198 3 sand sand NN cord-022526-j9kg00qf 198 4 or or CC cord-022526-j9kg00qf 198 5 gravel gravel NN cord-022526-j9kg00qf 198 6 are be VBP cord-022526-j9kg00qf 198 7 not not RB cord-022526-j9kg00qf 198 8 necessarily necessarily RB cord-022526-j9kg00qf 198 9 abnormal abnormal JJ cord-022526-j9kg00qf 198 10 . . . cord-022526-j9kg00qf 199 1 However however RB cord-022526-j9kg00qf 199 2 , , , cord-022526-j9kg00qf 199 3 a a DT cord-022526-j9kg00qf 199 4 significant significant JJ cord-022526-j9kg00qf 199 5 amount amount NN cord-022526-j9kg00qf 199 6 of of IN cord-022526-j9kg00qf 199 7 sand sand NN cord-022526-j9kg00qf 199 8 implies imply VBZ cord-022526-j9kg00qf 199 9 that that IN cord-022526-j9kg00qf 199 10 large large JJ cord-022526-j9kg00qf 199 11 quantities quantity NNS cord-022526-j9kg00qf 199 12 are be VBP cord-022526-j9kg00qf 199 13 present present JJ cord-022526-j9kg00qf 199 14 in in IN cord-022526-j9kg00qf 199 15 the the DT cord-022526-j9kg00qf 199 16 colon colon NN cord-022526-j9kg00qf 199 17 . . . cord-022526-j9kg00qf 200 1 Frank frank JJ cord-022526-j9kg00qf 200 2 blood blood NN cord-022526-j9kg00qf 200 3 indicates indicate VBZ cord-022526-j9kg00qf 200 4 substantial substantial JJ cord-022526-j9kg00qf 200 5 bleeding bleeding NN cord-022526-j9kg00qf 200 6 into into IN cord-022526-j9kg00qf 200 7 the the DT cord-022526-j9kg00qf 200 8 distal distal JJ cord-022526-j9kg00qf 200 9 colon colon NN cord-022526-j9kg00qf 200 10 ( ( -LRB- cord-022526-j9kg00qf 200 11 right right JJ cord-022526-j9kg00qf 200 12 dorsal dorsal JJ cord-022526-j9kg00qf 200 13 colon colon NN cord-022526-j9kg00qf 200 14 and/or and/or CC cord-022526-j9kg00qf 200 15 small small JJ cord-022526-j9kg00qf 200 16 colon colon NN cord-022526-j9kg00qf 200 17 ) ) -RRB- cord-022526-j9kg00qf 200 18 from from IN cord-022526-j9kg00qf 200 19 mucosal mucosal JJ cord-022526-j9kg00qf 200 20 damage damage NN cord-022526-j9kg00qf 200 21 . . . cord-022526-j9kg00qf 201 1 Laboratory laboratory NN cord-022526-j9kg00qf 201 2 analysis analysis NN cord-022526-j9kg00qf 201 3 of of IN cord-022526-j9kg00qf 201 4 the the DT cord-022526-j9kg00qf 201 5 feces fece NNS cord-022526-j9kg00qf 201 6 is be VBZ cord-022526-j9kg00qf 201 7 performed perform VBN cord-022526-j9kg00qf 201 8 frequently frequently RB cord-022526-j9kg00qf 201 9 in in IN cord-022526-j9kg00qf 201 10 cases case NNS cord-022526-j9kg00qf 201 11 of of IN cord-022526-j9kg00qf 201 12 diarrhea diarrhea NN cord-022526-j9kg00qf 201 13 . . . cord-022526-j9kg00qf 202 1 Fecal fecal JJ cord-022526-j9kg00qf 202 2 cytologic cytologic JJ cord-022526-j9kg00qf 202 3 examination examination NN cord-022526-j9kg00qf 202 4 and and CC cord-022526-j9kg00qf 202 5 tests test NNS cord-022526-j9kg00qf 202 6 for for IN cord-022526-j9kg00qf 202 7 occult occult JJ cord-022526-j9kg00qf 202 8 blood blood NN cord-022526-j9kg00qf 202 9 detect detect VBP cord-022526-j9kg00qf 202 10 mucosal mucosal JJ cord-022526-j9kg00qf 202 11 inflammation inflammation NN cord-022526-j9kg00qf 202 12 , , , cord-022526-j9kg00qf 202 13 SECTION section NN cord-022526-j9kg00qf 202 14 13.1 13.1 CD cord-022526-j9kg00qf 202 15 Examination examination NN cord-022526-j9kg00qf 202 16 for for IN cord-022526-j9kg00qf 202 17 Disorders disorder NNS cord-022526-j9kg00qf 202 18 of of IN cord-022526-j9kg00qf 202 19 the the DT cord-022526-j9kg00qf 202 20 Gastrointestinal Gastrointestinal NNP cord-022526-j9kg00qf 202 21 Tract Tract NNP cord-022526-j9kg00qf 202 22 erosion erosion NN cord-022526-j9kg00qf 202 23 , , , cord-022526-j9kg00qf 202 24 or or CC cord-022526-j9kg00qf 202 25 ulceration ulceration NN cord-022526-j9kg00qf 202 26 . . . cord-022526-j9kg00qf 203 1 Severe severe JJ cord-022526-j9kg00qf 203 2 inflammatory inflammatory JJ cord-022526-j9kg00qf 203 3 diseases disease NNS cord-022526-j9kg00qf 203 4 in in IN cord-022526-j9kg00qf 203 5 human human JJ cord-022526-j9kg00qf 203 6 beings being NNS cord-022526-j9kg00qf 203 7 , , , cord-022526-j9kg00qf 203 8 invasive invasive JJ cord-022526-j9kg00qf 203 9 bacterial bacterial JJ cord-022526-j9kg00qf 203 10 infections infection NNS cord-022526-j9kg00qf 203 11 in in IN cord-022526-j9kg00qf 203 12 particular particular JJ cord-022526-j9kg00qf 203 13 , , , cord-022526-j9kg00qf 203 14 have have VBP cord-022526-j9kg00qf 203 15 been be VBN cord-022526-j9kg00qf 203 16 shown show VBN cord-022526-j9kg00qf 203 17 to to TO cord-022526-j9kg00qf 203 18 increase increase VB cord-022526-j9kg00qf 203 19 the the DT cord-022526-j9kg00qf 203 20 shedding shedding NN cord-022526-j9kg00qf 203 21 of of IN cord-022526-j9kg00qf 203 22 leukocytes leukocyte NNS cord-022526-j9kg00qf 203 23 in in IN cord-022526-j9kg00qf 203 24 the the DT cord-022526-j9kg00qf 203 25 feces fece NNS cord-022526-j9kg00qf 203 26 . . . cord-022526-j9kg00qf 204 1 A a DT cord-022526-j9kg00qf 204 2 higher high JJR cord-022526-j9kg00qf 204 3 percentage percentage NN cord-022526-j9kg00qf 204 4 of of IN cord-022526-j9kg00qf 204 5 horses horse NNS cord-022526-j9kg00qf 204 6 with with IN cord-022526-j9kg00qf 204 7 salmonellosis salmonellosis NN cord-022526-j9kg00qf 204 8 and and CC cord-022526-j9kg00qf 204 9 diarrhea diarrhea NN cord-022526-j9kg00qf 204 10 have have VBP cord-022526-j9kg00qf 204 11 fecal fecal JJ cord-022526-j9kg00qf 204 12 leukocyte leukocyte NN cord-022526-j9kg00qf 204 13 counts count VBZ cord-022526-j9kg00qf 204 14 greater great JJR cord-022526-j9kg00qf 204 15 than than IN cord-022526-j9kg00qf 204 16 10 10 CD cord-022526-j9kg00qf 204 17 cells cell NNS cord-022526-j9kg00qf 204 18 per per IN cord-022526-j9kg00qf 204 19 high high JJ cord-022526-j9kg00qf 204 20 power power NN cord-022526-j9kg00qf 204 21 field field NN cord-022526-j9kg00qf 204 22 than than IN cord-022526-j9kg00qf 204 23 horses horse NNS cord-022526-j9kg00qf 204 24 with with IN cord-022526-j9kg00qf 204 25 negative negative JJ cord-022526-j9kg00qf 204 26 fecal fecal JJ cord-022526-j9kg00qf 204 27 cultures culture NNS cord-022526-j9kg00qf 204 28 for for IN cord-022526-j9kg00qf 204 29 Salmonella Salmonella NNP cord-022526-j9kg00qf 204 30 . . . cord-022526-j9kg00qf 205 1 These these DT cord-022526-j9kg00qf 205 2 results result NNS cord-022526-j9kg00qf 205 3 suggest suggest VBP cord-022526-j9kg00qf 205 4 that that IN cord-022526-j9kg00qf 205 5 high high JJ cord-022526-j9kg00qf 205 6 fecal fecal JJ cord-022526-j9kg00qf 205 7 leukocyte leukocyte NN cord-022526-j9kg00qf 205 8 counts count NNS cord-022526-j9kg00qf 205 9 indicate indicate VBP cord-022526-j9kg00qf 205 10 salmonellosis salmonellosis NN cord-022526-j9kg00qf 205 11 in in IN cord-022526-j9kg00qf 205 12 horses horse NNS cord-022526-j9kg00qf 205 13 with with IN cord-022526-j9kg00qf 205 14 diarrhea diarrhea NN cord-022526-j9kg00qf 205 15 . . . cord-022526-j9kg00qf 206 1 However however RB cord-022526-j9kg00qf 206 2 , , , cord-022526-j9kg00qf 206 3 the the DT cord-022526-j9kg00qf 206 4 specificity specificity NN cord-022526-j9kg00qf 206 5 of of IN cord-022526-j9kg00qf 206 6 this this DT cord-022526-j9kg00qf 206 7 test test NN cord-022526-j9kg00qf 206 8 is be VBZ cord-022526-j9kg00qf 206 9 probably probably RB cord-022526-j9kg00qf 206 10 low low JJ cord-022526-j9kg00qf 206 11 . . . cord-022526-j9kg00qf 207 1 Low low JJ cord-022526-j9kg00qf 207 2 fecal fecal JJ cord-022526-j9kg00qf 207 3 leukocyte leukocyte NN cord-022526-j9kg00qf 207 4 counts count NNS cord-022526-j9kg00qf 207 5 do do VBP cord-022526-j9kg00qf 207 6 not not RB cord-022526-j9kg00qf 207 7 rule rule VB cord-022526-j9kg00qf 207 8 out out RP cord-022526-j9kg00qf 207 9 salmonellosis salmonellosis NN cord-022526-j9kg00qf 207 10 . . . cord-022526-j9kg00qf 208 1 31 31 CD cord-022526-j9kg00qf 208 2 Fecal fecal JJ cord-022526-j9kg00qf 208 3 occult occult JJ cord-022526-j9kg00qf 208 4 blood blood NN cord-022526-j9kg00qf 208 5 tests test NNS cord-022526-j9kg00qf 208 6 detect detect VBP cord-022526-j9kg00qf 208 7 blood blood NN cord-022526-j9kg00qf 208 8 in in IN cord-022526-j9kg00qf 208 9 the the DT cord-022526-j9kg00qf 208 10 feces fece NNS cord-022526-j9kg00qf 208 11 , , , cord-022526-j9kg00qf 208 12 presumably presumably RB cord-022526-j9kg00qf 208 13 from from IN cord-022526-j9kg00qf 208 14 erosion erosion NN cord-022526-j9kg00qf 208 15 or or CC cord-022526-j9kg00qf 208 16 ulceration ulceration NN cord-022526-j9kg00qf 208 17 of of IN cord-022526-j9kg00qf 208 18 the the DT cord-022526-j9kg00qf 208 19 mucosa mucosa NN cord-022526-j9kg00qf 208 20 , , , cord-022526-j9kg00qf 208 21 but but CC cord-022526-j9kg00qf 208 22 do do VBP cord-022526-j9kg00qf 208 23 not not RB cord-022526-j9kg00qf 208 24 distinguish distinguish VB cord-022526-j9kg00qf 208 25 the the DT cord-022526-j9kg00qf 208 26 source source NN cord-022526-j9kg00qf 208 27 of of IN cord-022526-j9kg00qf 208 28 the the DT cord-022526-j9kg00qf 208 29 blood blood NN cord-022526-j9kg00qf 208 30 . . . cord-022526-j9kg00qf 209 1 Large large JJ cord-022526-j9kg00qf 209 2 volumes volume NNS cord-022526-j9kg00qf 209 3 of of IN cord-022526-j9kg00qf 209 4 blood blood NN cord-022526-j9kg00qf 209 5 ( ( -LRB- cord-022526-j9kg00qf 209 6 1 1 CD cord-022526-j9kg00qf 209 7 to to IN cord-022526-j9kg00qf 209 8 2 2 CD cord-022526-j9kg00qf 209 9 L l NN cord-022526-j9kg00qf 209 10 ) ) -RRB- cord-022526-j9kg00qf 209 11 given give VBN cord-022526-j9kg00qf 209 12 by by IN cord-022526-j9kg00qf 209 13 nasogastric nasogastric NN cord-022526-j9kg00qf 209 14 tube tube NN cord-022526-j9kg00qf 209 15 were be VBD cord-022526-j9kg00qf 209 16 required require VBN cord-022526-j9kg00qf 209 17 to to TO cord-022526-j9kg00qf 209 18 produce produce VB cord-022526-j9kg00qf 209 19 a a DT cord-022526-j9kg00qf 209 20 positive positive JJ cord-022526-j9kg00qf 209 21 test test NN cord-022526-j9kg00qf 209 22 for for IN cord-022526-j9kg00qf 209 23 occult occult JJ cord-022526-j9kg00qf 209 24 blood blood NN cord-022526-j9kg00qf 209 25 in in IN cord-022526-j9kg00qf 209 26 the the DT cord-022526-j9kg00qf 209 27 feces fece NNS cord-022526-j9kg00qf 209 28 , , , cord-022526-j9kg00qf 209 29 but but CC cord-022526-j9kg00qf 209 30 the the DT cord-022526-j9kg00qf 209 31 amount amount NN cord-022526-j9kg00qf 209 32 of of IN cord-022526-j9kg00qf 209 33 blood blood NN cord-022526-j9kg00qf 209 34 originating originate VBG cord-022526-j9kg00qf 209 35 from from IN cord-022526-j9kg00qf 209 36 the the DT cord-022526-j9kg00qf 209 37 large large JJ cord-022526-j9kg00qf 209 38 intestine intestine NN cord-022526-j9kg00qf 209 39 required require VBN cord-022526-j9kg00qf 209 40 to to TO cord-022526-j9kg00qf 209 41 produce produce VB cord-022526-j9kg00qf 209 42 a a DT cord-022526-j9kg00qf 209 43 positive positive JJ cord-022526-j9kg00qf 209 44 test test NN cord-022526-j9kg00qf 209 45 is be VBZ cord-022526-j9kg00qf 209 46 unknown unknown JJ cord-022526-j9kg00qf 209 47 . . . cord-022526-j9kg00qf 210 1 A a DT cord-022526-j9kg00qf 210 2 positive positive JJ cord-022526-j9kg00qf 210 3 test test NN cord-022526-j9kg00qf 210 4 implies imply VBZ cord-022526-j9kg00qf 210 5 significant significant JJ cord-022526-j9kg00qf 210 6 hemorrhage hemorrhage NN cord-022526-j9kg00qf 210 7 into into IN cord-022526-j9kg00qf 210 8 the the DT cord-022526-j9kg00qf 210 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 210 10 tract tract NN cord-022526-j9kg00qf 210 11 . . . cord-022526-j9kg00qf 211 1 Newer new JJR cord-022526-j9kg00qf 211 2 , , , cord-022526-j9kg00qf 211 3 more more RBR cord-022526-j9kg00qf 211 4 sensitive sensitive JJ cord-022526-j9kg00qf 211 5 tests test NNS cord-022526-j9kg00qf 211 6 detect detect VBP cord-022526-j9kg00qf 211 7 not not RB cord-022526-j9kg00qf 211 8 only only RB cord-022526-j9kg00qf 211 9 occult occult JJ cord-022526-j9kg00qf 211 10 blood blood NN cord-022526-j9kg00qf 211 11 but but CC cord-022526-j9kg00qf 211 12 also also RB cord-022526-j9kg00qf 211 13 degraded degrade VBD cord-022526-j9kg00qf 211 14 blood blood NN cord-022526-j9kg00qf 211 15 and and CC cord-022526-j9kg00qf 211 16 may may MD cord-022526-j9kg00qf 211 17 be be VB cord-022526-j9kg00qf 211 18 useful useful JJ cord-022526-j9kg00qf 211 19 to to TO cord-022526-j9kg00qf 211 20 determine determine VB cord-022526-j9kg00qf 211 21 the the DT cord-022526-j9kg00qf 211 22 site site NN cord-022526-j9kg00qf 211 23 and and CC cord-022526-j9kg00qf 211 24 quantity quantity NN cord-022526-j9kg00qf 211 25 of of IN cord-022526-j9kg00qf 211 26 blood blood NN cord-022526-j9kg00qf 211 27 loss loss NN cord-022526-j9kg00qf 211 28 . . . cord-022526-j9kg00qf 212 1 32 32 CD cord-022526-j9kg00qf 213 1 A a DT cord-022526-j9kg00qf 213 2 positive positive JJ cord-022526-j9kg00qf 213 3 test test NN cord-022526-j9kg00qf 213 4 implies imply VBZ cord-022526-j9kg00qf 213 5 significant significant JJ cord-022526-j9kg00qf 213 6 hemorrhage hemorrhage NN cord-022526-j9kg00qf 213 7 into into IN cord-022526-j9kg00qf 213 8 the the DT cord-022526-j9kg00qf 213 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 213 10 tract tract NN cord-022526-j9kg00qf 213 11 . . . cord-022526-j9kg00qf 214 1 Bacteriologic Bacteriologic NNP cord-022526-j9kg00qf 214 2 examination examination NN cord-022526-j9kg00qf 214 3 of of IN cord-022526-j9kg00qf 214 4 the the DT cord-022526-j9kg00qf 214 5 fecal fecal JJ cord-022526-j9kg00qf 214 6 flora flora NNP cord-022526-j9kg00qf 214 7 has have VBZ cord-022526-j9kg00qf 214 8 been be VBN cord-022526-j9kg00qf 214 9 used use VBN cord-022526-j9kg00qf 214 10 to to TO cord-022526-j9kg00qf 214 11 quantitate quantitate VB cord-022526-j9kg00qf 214 12 specific specific JJ cord-022526-j9kg00qf 214 13 bacterial bacterial JJ cord-022526-j9kg00qf 214 14 species specie NNS cord-022526-j9kg00qf 214 15 in in IN cord-022526-j9kg00qf 214 16 the the DT cord-022526-j9kg00qf 214 17 feces fece NNS cord-022526-j9kg00qf 214 18 of of IN cord-022526-j9kg00qf 214 19 horses horse NNS cord-022526-j9kg00qf 214 20 with with IN cord-022526-j9kg00qf 214 21 diarrhea diarrhea NN cord-022526-j9kg00qf 214 22 . . . cord-022526-j9kg00qf 215 1 Quantitation quantitation NN cord-022526-j9kg00qf 215 2 of of IN cord-022526-j9kg00qf 215 3 clostridial clostridial JJ cord-022526-j9kg00qf 215 4 species specie NNS cord-022526-j9kg00qf 215 5 may may MD cord-022526-j9kg00qf 215 6 be be VB cord-022526-j9kg00qf 215 7 beneficial beneficial JJ cord-022526-j9kg00qf 215 8 in in IN cord-022526-j9kg00qf 215 9 diagnosing diagnose VBG cord-022526-j9kg00qf 215 10 clostridial clostridial JJ cord-022526-j9kg00qf 215 11 infection infection NN cord-022526-j9kg00qf 215 12 of of IN cord-022526-j9kg00qf 215 13 the the DT cord-022526-j9kg00qf 215 14 large large JJ cord-022526-j9kg00qf 215 15 intestine intestine NN cord-022526-j9kg00qf 215 16 . . . cord-022526-j9kg00qf 216 1 33 33 CD cord-022526-j9kg00qf 216 2 Tests test NNS cord-022526-j9kg00qf 216 3 to to TO cord-022526-j9kg00qf 216 4 detect detect VB cord-022526-j9kg00qf 216 5 clostridial clostridial JJ cord-022526-j9kg00qf 216 6 toxins toxin NNS cord-022526-j9kg00qf 216 7 in in IN cord-022526-j9kg00qf 216 8 intestinal intestinal JJ cord-022526-j9kg00qf 216 9 contents content NNS cord-022526-j9kg00qf 216 10 or or CC cord-022526-j9kg00qf 216 11 feces fece NNS cord-022526-j9kg00qf 216 12 are be VBP cord-022526-j9kg00qf 216 13 important important JJ cord-022526-j9kg00qf 216 14 to to TO cord-022526-j9kg00qf 216 15 determine determine VB cord-022526-j9kg00qf 216 16 whether whether IN cord-022526-j9kg00qf 216 17 clostridia clostridia NNP cord-022526-j9kg00qf 216 18 cultured culture VBN cord-022526-j9kg00qf 216 19 from from IN cord-022526-j9kg00qf 216 20 the the DT cord-022526-j9kg00qf 216 21 feces fece NNS cord-022526-j9kg00qf 216 22 are be VBP cord-022526-j9kg00qf 216 23 causing cause VBG cord-022526-j9kg00qf 216 24 disease disease NN cord-022526-j9kg00qf 216 25 . . . cord-022526-j9kg00qf 217 1 The the DT cord-022526-j9kg00qf 217 2 most most RBS cord-022526-j9kg00qf 217 3 common common JJ cord-022526-j9kg00qf 217 4 bacterial bacterial JJ cord-022526-j9kg00qf 217 5 pathogens pathogen NNS cord-022526-j9kg00qf 217 6 isolated isolate VBN cord-022526-j9kg00qf 217 7 from from IN cord-022526-j9kg00qf 217 8 the the DT cord-022526-j9kg00qf 217 9 feces fece NNS cord-022526-j9kg00qf 217 10 of of IN cord-022526-j9kg00qf 217 11 horses horse NNS cord-022526-j9kg00qf 217 12 are be VBP cord-022526-j9kg00qf 217 13 Salmonella salmonella NN cord-022526-j9kg00qf 217 14 and and CC cord-022526-j9kg00qf 217 15 Clostridium Clostridium NNP cord-022526-j9kg00qf 217 16 . . . cord-022526-j9kg00qf 218 1 The the DT cord-022526-j9kg00qf 218 2 number number NN cord-022526-j9kg00qf 218 3 of of IN cord-022526-j9kg00qf 218 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 218 5 organisms organism NNS cord-022526-j9kg00qf 218 6 isolated isolate VBN cord-022526-j9kg00qf 218 7 from from IN cord-022526-j9kg00qf 218 8 the the DT cord-022526-j9kg00qf 218 9 feces fece NNS cord-022526-j9kg00qf 218 10 of of IN cord-022526-j9kg00qf 218 11 horses horse NNS cord-022526-j9kg00qf 218 12 with with IN cord-022526-j9kg00qf 218 13 clinical clinical JJ cord-022526-j9kg00qf 218 14 salmonellosis salmonellosis NN cord-022526-j9kg00qf 218 15 is be VBZ cord-022526-j9kg00qf 218 16 usually usually RB cord-022526-j9kg00qf 218 17 higher high JJR cord-022526-j9kg00qf 218 18 than than IN cord-022526-j9kg00qf 218 19 from from IN cord-022526-j9kg00qf 218 20 horses horse NNS cord-022526-j9kg00qf 218 21 with with IN cord-022526-j9kg00qf 218 22 asymptomatic asymptomatic JJ cord-022526-j9kg00qf 218 23 infections infection NNS cord-022526-j9kg00qf 218 24 . . . cord-022526-j9kg00qf 219 1 However however RB cord-022526-j9kg00qf 219 2 , , , cord-022526-j9kg00qf 219 3 the the DT cord-022526-j9kg00qf 219 4 volume volume NN cord-022526-j9kg00qf 219 5 of of IN cord-022526-j9kg00qf 219 6 feces fece NNS cord-022526-j9kg00qf 219 7 in in IN cord-022526-j9kg00qf 219 8 many many JJ cord-022526-j9kg00qf 219 9 cases case NNS cord-022526-j9kg00qf 219 10 of of IN cord-022526-j9kg00qf 219 11 acute acute JJ cord-022526-j9kg00qf 219 12 diarrhea diarrhea NN cord-022526-j9kg00qf 219 13 is be VBZ cord-022526-j9kg00qf 219 14 high high JJ cord-022526-j9kg00qf 219 15 , , , cord-022526-j9kg00qf 219 16 and and CC cord-022526-j9kg00qf 219 17 the the DT cord-022526-j9kg00qf 219 18 concentration concentration NN cord-022526-j9kg00qf 219 19 of of IN cord-022526-j9kg00qf 219 20 Salmonella Salmonella NNP cord-022526-j9kg00qf 219 21 organisms organism NNS cord-022526-j9kg00qf 219 22 may may MD cord-022526-j9kg00qf 219 23 be be VB cord-022526-j9kg00qf 219 24 lower low JJR cord-022526-j9kg00qf 219 25 than than IN cord-022526-j9kg00qf 219 26 would would MD cord-022526-j9kg00qf 219 27 be be VB cord-022526-j9kg00qf 219 28 expected expect VBN cord-022526-j9kg00qf 219 29 , , , cord-022526-j9kg00qf 219 30 accounting account VBG cord-022526-j9kg00qf 219 31 for for IN cord-022526-j9kg00qf 219 32 many many JJ cord-022526-j9kg00qf 219 33 false false JJ cord-022526-j9kg00qf 219 34 - - HYPH cord-022526-j9kg00qf 219 35 negative negative JJ cord-022526-j9kg00qf 219 36 fecal fecal JJ cord-022526-j9kg00qf 219 37 cultures culture NNS cord-022526-j9kg00qf 219 38 . . . cord-022526-j9kg00qf 220 1 The the DT cord-022526-j9kg00qf 220 2 sensitivity sensitivity NN cord-022526-j9kg00qf 220 3 of of IN cord-022526-j9kg00qf 220 4 fecal fecal JJ cord-022526-j9kg00qf 220 5 cultures culture NNS cord-022526-j9kg00qf 220 6 for for IN cord-022526-j9kg00qf 220 7 detecting detect VBG cord-022526-j9kg00qf 220 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 220 9 infection infection NN cord-022526-j9kg00qf 220 10 may may MD cord-022526-j9kg00qf 220 11 be be VB cord-022526-j9kg00qf 220 12 as as RB cord-022526-j9kg00qf 220 13 low low JJ cord-022526-j9kg00qf 220 14 as as IN cord-022526-j9kg00qf 220 15 20 20 CD cord-022526-j9kg00qf 220 16 % % NN cord-022526-j9kg00qf 220 17 . . . cord-022526-j9kg00qf 221 1 Culture culture NN cord-022526-j9kg00qf 221 2 of of IN cord-022526-j9kg00qf 221 3 five five CD cord-022526-j9kg00qf 221 4 consecutive consecutive JJ cord-022526-j9kg00qf 221 5 daily daily JJ cord-022526-j9kg00qf 221 6 fecal fecal JJ cord-022526-j9kg00qf 221 7 samples sample NNS cord-022526-j9kg00qf 221 8 is be VBZ cord-022526-j9kg00qf 221 9 recommended recommend VBN cord-022526-j9kg00qf 221 10 to to TO cord-022526-j9kg00qf 221 11 increase increase VB cord-022526-j9kg00qf 221 12 the the DT cord-022526-j9kg00qf 221 13 sensitivity sensitivity NN cord-022526-j9kg00qf 221 14 of of IN cord-022526-j9kg00qf 221 15 the the DT cord-022526-j9kg00qf 221 16 test test NN cord-022526-j9kg00qf 221 17 . . . cord-022526-j9kg00qf 222 1 Because because IN cord-022526-j9kg00qf 222 2 salmonellae salmonella NNS cord-022526-j9kg00qf 222 3 are be VBP cord-022526-j9kg00qf 222 4 intracellular intracellular JJ cord-022526-j9kg00qf 222 5 organisms organism NNS cord-022526-j9kg00qf 222 6 , , , cord-022526-j9kg00qf 222 7 culture culture NN cord-022526-j9kg00qf 222 8 of of IN cord-022526-j9kg00qf 222 9 rectal rectal JJ cord-022526-j9kg00qf 222 10 scrapings scraping NNS cord-022526-j9kg00qf 222 11 or or CC cord-022526-j9kg00qf 222 12 a a DT cord-022526-j9kg00qf 222 13 rectal rectal JJ cord-022526-j9kg00qf 222 14 biopsy biopsy NN cord-022526-j9kg00qf 222 15 sample sample NN cord-022526-j9kg00qf 222 16 , , , cord-022526-j9kg00qf 222 17 along along IN cord-022526-j9kg00qf 222 18 with with IN cord-022526-j9kg00qf 222 19 fecal fecal JJ cord-022526-j9kg00qf 222 20 material material NN cord-022526-j9kg00qf 222 21 , , , cord-022526-j9kg00qf 222 22 may may MD cord-022526-j9kg00qf 222 23 increase increase VB cord-022526-j9kg00qf 222 24 the the DT cord-022526-j9kg00qf 222 25 sensitivity sensitivity NN cord-022526-j9kg00qf 222 26 of of IN cord-022526-j9kg00qf 222 27 culture culture NN cord-022526-j9kg00qf 222 28 for for IN cord-022526-j9kg00qf 222 29 detecting detect VBG cord-022526-j9kg00qf 222 30 Salmonella Salmonella NNP cord-022526-j9kg00qf 222 31 infection infection NN cord-022526-j9kg00qf 222 32 to to IN cord-022526-j9kg00qf 222 33 50 50 CD cord-022526-j9kg00qf 222 34 % % NN cord-022526-j9kg00qf 222 35 . . . cord-022526-j9kg00qf 223 1 34 34 CD cord-022526-j9kg00qf 223 2 One one PRP cord-022526-j9kg00qf 223 3 can can MD cord-022526-j9kg00qf 223 4 perform perform VB cord-022526-j9kg00qf 223 5 a a DT cord-022526-j9kg00qf 223 6 polymerase polymerase NN cord-022526-j9kg00qf 223 7 chain chain NN cord-022526-j9kg00qf 223 8 reaction reaction NN cord-022526-j9kg00qf 223 9 assay assay NN cord-022526-j9kg00qf 223 10 on on IN cord-022526-j9kg00qf 223 11 fecal fecal JJ cord-022526-j9kg00qf 223 12 samples sample NNS cord-022526-j9kg00qf 223 13 to to TO cord-022526-j9kg00qf 223 14 detect detect VB cord-022526-j9kg00qf 223 15 DNA DNA NNP cord-022526-j9kg00qf 223 16 from from IN cord-022526-j9kg00qf 223 17 Salmonella Salmonella NNP cord-022526-j9kg00qf 223 18 sp sp NNP cord-022526-j9kg00qf 223 19 . . . cord-022526-j9kg00qf 224 1 The the DT cord-022526-j9kg00qf 224 2 polymerase polymerase NN cord-022526-j9kg00qf 224 3 chain chain NN cord-022526-j9kg00qf 224 4 reaction reaction NN cord-022526-j9kg00qf 224 5 test test NN cord-022526-j9kg00qf 224 6 is be VBZ cord-022526-j9kg00qf 224 7 more more RBR cord-022526-j9kg00qf 224 8 sensitive sensitive JJ cord-022526-j9kg00qf 224 9 than than IN cord-022526-j9kg00qf 224 10 culture culture NN cord-022526-j9kg00qf 224 11 and and CC cord-022526-j9kg00qf 224 12 is be VBZ cord-022526-j9kg00qf 224 13 frequently frequently RB cord-022526-j9kg00qf 224 14 positive positive JJ cord-022526-j9kg00qf 224 15 in in IN cord-022526-j9kg00qf 224 16 clinically clinically RB cord-022526-j9kg00qf 224 17 normal normal JJ cord-022526-j9kg00qf 224 18 horses horse NNS cord-022526-j9kg00qf 224 19 that that WDT cord-022526-j9kg00qf 224 20 continuously continuously RB cord-022526-j9kg00qf 224 21 shed shed VBD cord-022526-j9kg00qf 224 22 small small JJ cord-022526-j9kg00qf 224 23 amounts amount NNS cord-022526-j9kg00qf 224 24 of of IN cord-022526-j9kg00qf 224 25 bacteria bacteria NNS cord-022526-j9kg00qf 224 26 . . . cord-022526-j9kg00qf 225 1 Polymerase polymerase NN cord-022526-j9kg00qf 225 2 chain chain NN cord-022526-j9kg00qf 225 3 reaction reaction NN cord-022526-j9kg00qf 225 4 or or CC cord-022526-j9kg00qf 225 5 immunologic immunologic JJ cord-022526-j9kg00qf 225 6 tests test NNS cord-022526-j9kg00qf 225 7 also also RB cord-022526-j9kg00qf 225 8 may may MD cord-022526-j9kg00qf 225 9 detect detect VB cord-022526-j9kg00qf 225 10 Clostridium clostridium NN cord-022526-j9kg00qf 225 11 perfringens perfringen NNS cord-022526-j9kg00qf 225 12 and and CC cord-022526-j9kg00qf 225 13 C. C. NNP cord-022526-j9kg00qf 225 14 difficile difficile NN cord-022526-j9kg00qf 225 15 exotoxins exotoxin VBZ cord-022526-j9kg00qf 225 16 in in IN cord-022526-j9kg00qf 225 17 the the DT cord-022526-j9kg00qf 225 18 feces fece NNS cord-022526-j9kg00qf 225 19 . . . cord-022526-j9kg00qf 226 1 Qualitative qualitative JJ cord-022526-j9kg00qf 226 2 fecal fecal JJ cord-022526-j9kg00qf 226 3 examination examination NN cord-022526-j9kg00qf 226 4 is be VBZ cord-022526-j9kg00qf 226 5 a a DT cord-022526-j9kg00qf 226 6 technique technique NN cord-022526-j9kg00qf 226 7 to to TO cord-022526-j9kg00qf 226 8 detect detect VB cord-022526-j9kg00qf 226 9 nematode nematode NN cord-022526-j9kg00qf 226 10 and and CC cord-022526-j9kg00qf 226 11 cestode cestode NNP cord-022526-j9kg00qf 226 12 ova ova NNP cord-022526-j9kg00qf 226 13 , , , cord-022526-j9kg00qf 226 14 protozoan protozoan NN cord-022526-j9kg00qf 226 15 oocysts oocyst NNS cord-022526-j9kg00qf 226 16 , , , cord-022526-j9kg00qf 226 17 parasitic parasitic JJ cord-022526-j9kg00qf 226 18 larvae larva NNS cord-022526-j9kg00qf 226 19 , , , cord-022526-j9kg00qf 226 20 and and CC cord-022526-j9kg00qf 226 21 protozoan protozoan NN cord-022526-j9kg00qf 226 22 trophozoites trophozoite NNS cord-022526-j9kg00qf 226 23 . . . cord-022526-j9kg00qf 227 1 A a DT cord-022526-j9kg00qf 227 2 direct direct JJ cord-022526-j9kg00qf 227 3 smear smear NN cord-022526-j9kg00qf 227 4 of of IN cord-022526-j9kg00qf 227 5 fecal fecal JJ cord-022526-j9kg00qf 227 6 material material NN cord-022526-j9kg00qf 227 7 is be VBZ cord-022526-j9kg00qf 227 8 a a DT cord-022526-j9kg00qf 227 9 rapid rapid JJ cord-022526-j9kg00qf 227 10 method method NN cord-022526-j9kg00qf 227 11 to to TO cord-022526-j9kg00qf 227 12 screen screen VB cord-022526-j9kg00qf 227 13 feces fece NNS cord-022526-j9kg00qf 227 14 for for IN cord-022526-j9kg00qf 227 15 ova ova NN cord-022526-j9kg00qf 227 16 and and CC cord-022526-j9kg00qf 227 17 oocysts oocyst NNS cord-022526-j9kg00qf 227 18 , , , cord-022526-j9kg00qf 227 19 to to TO cord-022526-j9kg00qf 227 20 detect detect VB cord-022526-j9kg00qf 227 21 parasite parasite NN cord-022526-j9kg00qf 227 22 larvae larva NNS cord-022526-j9kg00qf 227 23 and and CC cord-022526-j9kg00qf 227 24 trophozoites trophozoite NNS cord-022526-j9kg00qf 227 25 , , , cord-022526-j9kg00qf 227 26 and and CC cord-022526-j9kg00qf 227 27 to to TO cord-022526-j9kg00qf 227 28 observe observe VB cord-022526-j9kg00qf 227 29 motility motility NN cord-022526-j9kg00qf 227 30 of of IN cord-022526-j9kg00qf 227 31 ciliates ciliate NNS cord-022526-j9kg00qf 227 32 and and CC cord-022526-j9kg00qf 227 33 parasite parasite NN cord-022526-j9kg00qf 227 34 larvae larva NNS cord-022526-j9kg00qf 227 35 . . . cord-022526-j9kg00qf 228 1 Fecal fecal JJ cord-022526-j9kg00qf 228 2 flotation flotation NN cord-022526-j9kg00qf 228 3 is be VBZ cord-022526-j9kg00qf 228 4 a a DT cord-022526-j9kg00qf 228 5 more more RBR cord-022526-j9kg00qf 228 6 sensitive sensitive JJ cord-022526-j9kg00qf 228 7 technique technique NN cord-022526-j9kg00qf 228 8 for for IN cord-022526-j9kg00qf 228 9 isolating isolate VBG cord-022526-j9kg00qf 228 10 and and CC cord-022526-j9kg00qf 228 11 detecting detect VBG cord-022526-j9kg00qf 228 12 ova ova NN cord-022526-j9kg00qf 228 13 and and CC cord-022526-j9kg00qf 228 14 oocysts oocyst NNS cord-022526-j9kg00qf 228 15 because because IN cord-022526-j9kg00qf 228 16 the the DT cord-022526-j9kg00qf 228 17 eggs egg NNS cord-022526-j9kg00qf 228 18 are be VBP cord-022526-j9kg00qf 228 19 concentrated concentrate VBN cord-022526-j9kg00qf 228 20 from from IN cord-022526-j9kg00qf 228 21 the the DT cord-022526-j9kg00qf 228 22 sample sample NN cord-022526-j9kg00qf 228 23 . . . cord-022526-j9kg00qf 229 1 Zinc zinc NN cord-022526-j9kg00qf 229 2 sulfate sulfate NN cord-022526-j9kg00qf 229 3 and and CC cord-022526-j9kg00qf 229 4 sucrose sucrose NN cord-022526-j9kg00qf 229 5 solutions solution NNS cord-022526-j9kg00qf 229 6 are be VBP cord-022526-j9kg00qf 229 7 often often RB cord-022526-j9kg00qf 229 8 used use VBN cord-022526-j9kg00qf 229 9 to to TO cord-022526-j9kg00qf 229 10 concentrate concentrate VB cord-022526-j9kg00qf 229 11 less less RBR cord-022526-j9kg00qf 229 12 dense dense JJ cord-022526-j9kg00qf 229 13 ova ova NN cord-022526-j9kg00qf 229 14 and and CC cord-022526-j9kg00qf 229 15 oocysts oocyst NNS cord-022526-j9kg00qf 229 16 . . . cord-022526-j9kg00qf 230 1 Zinc zinc NN cord-022526-j9kg00qf 230 2 sulfate sulfate NN cord-022526-j9kg00qf 230 3 produces produce VBZ cord-022526-j9kg00qf 230 4 less less JJR cord-022526-j9kg00qf 230 5 distortion distortion NN cord-022526-j9kg00qf 230 6 of of IN cord-022526-j9kg00qf 230 7 trophozoites trophozoite NNS cord-022526-j9kg00qf 230 8 and and CC cord-022526-j9kg00qf 230 9 larvae larva NNS cord-022526-j9kg00qf 230 10 than than IN cord-022526-j9kg00qf 230 11 sucrose sucrose NN cord-022526-j9kg00qf 230 12 solutions solution NNS cord-022526-j9kg00qf 230 13 . . . cord-022526-j9kg00qf 231 1 Fecal fecal JJ cord-022526-j9kg00qf 231 2 sedimentation sedimentation NN cord-022526-j9kg00qf 231 3 is be VBZ cord-022526-j9kg00qf 231 4 particularly particularly RB cord-022526-j9kg00qf 231 5 appropriate appropriate JJ cord-022526-j9kg00qf 231 6 for for IN cord-022526-j9kg00qf 231 7 ciliates ciliate NNS cord-022526-j9kg00qf 231 8 , , , cord-022526-j9kg00qf 231 9 Giardia Giardia NNP cord-022526-j9kg00qf 231 10 , , , cord-022526-j9kg00qf 231 11 and and CC cord-022526-j9kg00qf 231 12 trichomonads trichomonad NNS cord-022526-j9kg00qf 231 13 . . . cord-022526-j9kg00qf 232 1 Quantitative quantitative JJ cord-022526-j9kg00qf 232 2 techniques technique NNS cord-022526-j9kg00qf 232 3 such such JJ cord-022526-j9kg00qf 232 4 as as IN cord-022526-j9kg00qf 232 5 the the DT cord-022526-j9kg00qf 232 6 Cornell Cornell NNP cord-022526-j9kg00qf 232 7 - - HYPH cord-022526-j9kg00qf 232 8 McMaster McMaster NNP cord-022526-j9kg00qf 232 9 method method NN cord-022526-j9kg00qf 232 10 allow allow VB cord-022526-j9kg00qf 232 11 one one CD cord-022526-j9kg00qf 232 12 to to TO cord-022526-j9kg00qf 232 13 estimate estimate VB cord-022526-j9kg00qf 232 14 the the DT cord-022526-j9kg00qf 232 15 number number NN cord-022526-j9kg00qf 232 16 of of IN cord-022526-j9kg00qf 232 17 eggs egg NNS cord-022526-j9kg00qf 232 18 per per IN cord-022526-j9kg00qf 232 19 gram gram NN cord-022526-j9kg00qf 232 20 of of IN cord-022526-j9kg00qf 232 21 feces fece NNS cord-022526-j9kg00qf 232 22 and and CC cord-022526-j9kg00qf 232 23 are be VBP cord-022526-j9kg00qf 232 24 most most RBS cord-022526-j9kg00qf 232 25 appropriate appropriate JJ cord-022526-j9kg00qf 232 26 in in IN cord-022526-j9kg00qf 232 27 monitoring monitor VBG cord-022526-j9kg00qf 232 28 parasite parasite NN cord-022526-j9kg00qf 232 29 control control NN cord-022526-j9kg00qf 232 30 programs program NNS cord-022526-j9kg00qf 232 31 . . . cord-022526-j9kg00qf 233 1 35 35 CD cord-022526-j9kg00qf 233 2 _SP cord-022526-j9kg00qf 233 3 Survey Survey NNP cord-022526-j9kg00qf 233 4 radiography radiography NN cord-022526-j9kg00qf 233 5 of of IN cord-022526-j9kg00qf 233 6 the the DT cord-022526-j9kg00qf 233 7 normal normal JJ cord-022526-j9kg00qf 233 8 esophagus esophagus NN cord-022526-j9kg00qf 233 9 is be VBZ cord-022526-j9kg00qf 233 10 usually usually RB cord-022526-j9kg00qf 233 11 unrewarding unrewarding JJ cord-022526-j9kg00qf 233 12 but but CC cord-022526-j9kg00qf 233 13 may may MD cord-022526-j9kg00qf 233 14 be be VB cord-022526-j9kg00qf 233 15 useful useful JJ cord-022526-j9kg00qf 233 16 in in IN cord-022526-j9kg00qf 233 17 horses horse NNS cord-022526-j9kg00qf 233 18 with with IN cord-022526-j9kg00qf 233 19 esophageal esophageal JJ cord-022526-j9kg00qf 233 20 obstructions obstruction NNS cord-022526-j9kg00qf 233 21 to to TO cord-022526-j9kg00qf 233 22 determine determine VB cord-022526-j9kg00qf 233 23 the the DT cord-022526-j9kg00qf 233 24 extent extent NN cord-022526-j9kg00qf 233 25 and and CC cord-022526-j9kg00qf 233 26 location location NN cord-022526-j9kg00qf 233 27 of of IN cord-022526-j9kg00qf 233 28 the the DT cord-022526-j9kg00qf 233 29 obstruction obstruction NN cord-022526-j9kg00qf 233 30 . . . cord-022526-j9kg00qf 234 1 One one CD cord-022526-j9kg00qf 234 2 may may MD cord-022526-j9kg00qf 234 3 detect detect VB cord-022526-j9kg00qf 234 4 foreign foreign JJ cord-022526-j9kg00qf 234 5 bodies body NNS cord-022526-j9kg00qf 234 6 or or CC cord-022526-j9kg00qf 234 7 soft soft JJ cord-022526-j9kg00qf 234 8 tissue tissue NN cord-022526-j9kg00qf 234 9 masses masse NNS cord-022526-j9kg00qf 234 10 , , , cord-022526-j9kg00qf 234 11 and and CC cord-022526-j9kg00qf 234 12 in in IN cord-022526-j9kg00qf 234 13 cases case NNS cord-022526-j9kg00qf 234 14 of of IN cord-022526-j9kg00qf 234 15 esophageal esophageal JJ cord-022526-j9kg00qf 234 16 rupture rupture NN cord-022526-j9kg00qf 234 17 , , , cord-022526-j9kg00qf 234 18 one one PRP cord-022526-j9kg00qf 234 19 may may MD cord-022526-j9kg00qf 234 20 see see VB cord-022526-j9kg00qf 234 21 free free JJ cord-022526-j9kg00qf 234 22 air air NN cord-022526-j9kg00qf 234 23 and and CC cord-022526-j9kg00qf 234 24 ingesta ingesta NNP cord-022526-j9kg00qf 234 25 in in IN cord-022526-j9kg00qf 234 26 the the DT cord-022526-j9kg00qf 234 27 tissues tissue NNS cord-022526-j9kg00qf 234 28 surrounding surround VBG cord-022526-j9kg00qf 234 29 the the DT cord-022526-j9kg00qf 234 30 esophagus esophagus NN cord-022526-j9kg00qf 234 31 and and CC cord-022526-j9kg00qf 234 32 may may MD cord-022526-j9kg00qf 234 33 observe observe VB cord-022526-j9kg00qf 234 34 pneumomediastinum pneumomediastinum NNP cord-022526-j9kg00qf 234 35 . . . cord-022526-j9kg00qf 235 1 36 36 CD cord-022526-j9kg00qf 235 2 Thoracic thoracic JJ cord-022526-j9kg00qf 235 3 radiographs radiograph NNS cord-022526-j9kg00qf 235 4 may may MD cord-022526-j9kg00qf 235 5 be be VB cord-022526-j9kg00qf 235 6 necessary necessary JJ cord-022526-j9kg00qf 235 7 to to TO cord-022526-j9kg00qf 235 8 detect detect VB cord-022526-j9kg00qf 235 9 intrathoracic intrathoracic JJ cord-022526-j9kg00qf 235 10 esophageal esophageal JJ cord-022526-j9kg00qf 235 11 obstructions obstruction NNS cord-022526-j9kg00qf 235 12 , , , cord-022526-j9kg00qf 235 13 megaesophagus megaesophagus JJ cord-022526-j9kg00qf 235 14 , , , cord-022526-j9kg00qf 235 15 or or CC cord-022526-j9kg00qf 235 16 cranial cranial JJ cord-022526-j9kg00qf 235 17 mediastinal mediastinal JJ cord-022526-j9kg00qf 235 18 masses masse NNS cord-022526-j9kg00qf 235 19 causing cause VBG cord-022526-j9kg00qf 235 20 extraluminal extraluminal JJ cord-022526-j9kg00qf 235 21 obstruction obstruction NN cord-022526-j9kg00qf 235 22 . . . cord-022526-j9kg00qf 236 1 One one CD cord-022526-j9kg00qf 236 2 may may MD cord-022526-j9kg00qf 236 3 use use VB cord-022526-j9kg00qf 236 4 barium barium NN cord-022526-j9kg00qf 236 5 swallows swallow NNS cord-022526-j9kg00qf 236 6 or or CC cord-022526-j9kg00qf 236 7 double double JJ cord-022526-j9kg00qf 236 8 - - HYPH cord-022526-j9kg00qf 236 9 contrast contrast NN cord-022526-j9kg00qf 236 10 esophagrams esophagram NNS cord-022526-j9kg00qf 236 11 after after IN cord-022526-j9kg00qf 236 12 resolution resolution NN cord-022526-j9kg00qf 236 13 of of IN cord-022526-j9kg00qf 236 14 the the DT cord-022526-j9kg00qf 236 15 obstruction obstruction NN cord-022526-j9kg00qf 236 16 to to TO cord-022526-j9kg00qf 236 17 determine determine VB cord-022526-j9kg00qf 236 18 whether whether IN cord-022526-j9kg00qf 236 19 a a DT cord-022526-j9kg00qf 236 20 stricture stricture NN cord-022526-j9kg00qf 236 21 or or CC cord-022526-j9kg00qf 236 22 diverticulum diverticulum NN cord-022526-j9kg00qf 236 23 or or CC cord-022526-j9kg00qf 236 24 other other JJ cord-022526-j9kg00qf 236 25 underlying underlying JJ cord-022526-j9kg00qf 236 26 disorder disorder NN cord-022526-j9kg00qf 236 27 is be VBZ cord-022526-j9kg00qf 236 28 present present JJ cord-022526-j9kg00qf 236 29 . . . cord-022526-j9kg00qf 237 1 37 37 CD cord-022526-j9kg00qf 237 2 Barium barium NN cord-022526-j9kg00qf 237 3 sulfate sulfate NN cord-022526-j9kg00qf 237 4 is be VBZ cord-022526-j9kg00qf 237 5 the the DT cord-022526-j9kg00qf 237 6 usual usual JJ cord-022526-j9kg00qf 237 7 contrast contrast NN cord-022526-j9kg00qf 237 8 medium medium NN cord-022526-j9kg00qf 237 9 and and CC cord-022526-j9kg00qf 237 10 can can MD cord-022526-j9kg00qf 237 11 be be VB cord-022526-j9kg00qf 237 12 administered administer VBN cord-022526-j9kg00qf 237 13 orally orally RB cord-022526-j9kg00qf 237 14 via via IN cord-022526-j9kg00qf 237 15 a a DT cord-022526-j9kg00qf 237 16 dose dose NN cord-022526-j9kg00qf 237 17 syringe syringe NN cord-022526-j9kg00qf 237 18 or or CC cord-022526-j9kg00qf 237 19 by by IN cord-022526-j9kg00qf 237 20 nasogastric nasogastric NN cord-022526-j9kg00qf 237 21 tube tube NN cord-022526-j9kg00qf 237 22 ( ( -LRB- cord-022526-j9kg00qf 237 23 50 50 CD cord-022526-j9kg00qf 237 24 to to TO cord-022526-j9kg00qf 237 25 100 100 CD cord-022526-j9kg00qf 237 26 ml ml NNS cord-022526-j9kg00qf 237 27 of of IN cord-022526-j9kg00qf 237 28 a a DT cord-022526-j9kg00qf 237 29 40 40 CD cord-022526-j9kg00qf 237 30 % % NN cord-022526-j9kg00qf 237 31 barium barium NN cord-022526-j9kg00qf 237 32 sulfate sulfate NN cord-022526-j9kg00qf 237 33 suspension suspension NN cord-022526-j9kg00qf 237 34 or or CC cord-022526-j9kg00qf 237 35 barium barium NN cord-022526-j9kg00qf 237 36 paste paste NN cord-022526-j9kg00qf 237 37 ) ) -RRB- cord-022526-j9kg00qf 237 38 . . . cord-022526-j9kg00qf 238 1 Oral oral JJ cord-022526-j9kg00qf 238 2 administration administration NN cord-022526-j9kg00qf 238 3 is be VBZ cord-022526-j9kg00qf 238 4 preferred prefer VBN cord-022526-j9kg00qf 238 5 for for IN cord-022526-j9kg00qf 238 6 evaluation evaluation NN cord-022526-j9kg00qf 238 7 of of IN cord-022526-j9kg00qf 238 8 swallowing swallowing NN cord-022526-j9kg00qf 238 9 and and CC cord-022526-j9kg00qf 238 10 lesions lesion NNS cord-022526-j9kg00qf 238 11 in in IN cord-022526-j9kg00qf 238 12 the the DT cord-022526-j9kg00qf 238 13 proximal proximal JJ cord-022526-j9kg00qf 238 14 esophagus esophagus NN cord-022526-j9kg00qf 238 15 . . . cord-022526-j9kg00qf 239 1 Administration administration NN cord-022526-j9kg00qf 239 2 of of IN cord-022526-j9kg00qf 239 3 contrast contrast NN cord-022526-j9kg00qf 239 4 using use VBG cord-022526-j9kg00qf 239 5 a a DT cord-022526-j9kg00qf 239 6 nasogastric nasogastric NN cord-022526-j9kg00qf 239 7 tube tube NN cord-022526-j9kg00qf 239 8 ( ( -LRB- cord-022526-j9kg00qf 239 9 preferably preferably RB cord-022526-j9kg00qf 239 10 cuffed cuff VBN cord-022526-j9kg00qf 239 11 ) ) -RRB- cord-022526-j9kg00qf 239 12 allows allow VBZ cord-022526-j9kg00qf 239 13 for for IN cord-022526-j9kg00qf 239 14 delivery delivery NN cord-022526-j9kg00qf 239 15 of of IN cord-022526-j9kg00qf 239 16 larger large JJR cord-022526-j9kg00qf 239 17 volumes volume NNS cord-022526-j9kg00qf 239 18 of of IN cord-022526-j9kg00qf 239 19 barium barium NN cord-022526-j9kg00qf 239 20 ( ( -LRB- cord-022526-j9kg00qf 239 21 up up IN cord-022526-j9kg00qf 239 22 to to TO cord-022526-j9kg00qf 239 23 500 500 CD cord-022526-j9kg00qf 239 24 ml ml NNS cord-022526-j9kg00qf 239 25 ) ) -RRB- cord-022526-j9kg00qf 239 26 but but CC cord-022526-j9kg00qf 239 27 should should MD cord-022526-j9kg00qf 239 28 be be VB cord-022526-j9kg00qf 239 29 performed perform VBN cord-022526-j9kg00qf 239 30 without without IN cord-022526-j9kg00qf 239 31 sedation sedation NN cord-022526-j9kg00qf 239 32 if if IN cord-022526-j9kg00qf 239 33 possible possible JJ cord-022526-j9kg00qf 239 34 . . . cord-022526-j9kg00qf 240 1 One one PRP cord-022526-j9kg00qf 240 2 can can MD cord-022526-j9kg00qf 240 3 follow follow VB cord-022526-j9kg00qf 240 4 administration administration NN cord-022526-j9kg00qf 240 5 of of IN cord-022526-j9kg00qf 240 6 contrast contrast NN cord-022526-j9kg00qf 240 7 material material NN cord-022526-j9kg00qf 240 8 with with IN cord-022526-j9kg00qf 240 9 air air NN cord-022526-j9kg00qf 240 10 insufflation insufflation NN cord-022526-j9kg00qf 240 11 to to TO cord-022526-j9kg00qf 240 12 create create VB cord-022526-j9kg00qf 240 13 a a DT cord-022526-j9kg00qf 240 14 double double JJ cord-022526-j9kg00qf 240 15 - - HYPH cord-022526-j9kg00qf 240 16 contrast contrast NN cord-022526-j9kg00qf 240 17 effect effect NN cord-022526-j9kg00qf 240 18 . . . cord-022526-j9kg00qf 241 1 If if IN cord-022526-j9kg00qf 241 2 one one CD cord-022526-j9kg00qf 241 3 suspects suspect VBZ cord-022526-j9kg00qf 241 4 a a DT cord-022526-j9kg00qf 241 5 rupture rupture NN cord-022526-j9kg00qf 241 6 of of IN cord-022526-j9kg00qf 241 7 the the DT cord-022526-j9kg00qf 241 8 esophagus esophagus NN cord-022526-j9kg00qf 241 9 or or CC cord-022526-j9kg00qf 241 10 if if IN cord-022526-j9kg00qf 241 11 the the DT cord-022526-j9kg00qf 241 12 likelihood likelihood NN cord-022526-j9kg00qf 241 13 of of IN cord-022526-j9kg00qf 241 14 aspiration aspiration NN cord-022526-j9kg00qf 241 15 of of IN cord-022526-j9kg00qf 241 16 the the DT cord-022526-j9kg00qf 241 17 contrast contrast NN cord-022526-j9kg00qf 241 18 material material NN cord-022526-j9kg00qf 241 19 is be VBZ cord-022526-j9kg00qf 241 20 high high JJ cord-022526-j9kg00qf 241 21 , , , cord-022526-j9kg00qf 241 22 one one PRP cord-022526-j9kg00qf 241 23 should should MD cord-022526-j9kg00qf 241 24 use use VB cord-022526-j9kg00qf 241 25 iodinated iodinated JJ cord-022526-j9kg00qf 241 26 organic organic JJ cord-022526-j9kg00qf 241 27 compounds compound NNS cord-022526-j9kg00qf 241 28 in in IN cord-022526-j9kg00qf 241 29 an an DT cord-022526-j9kg00qf 241 30 aqueous aqueous JJ cord-022526-j9kg00qf 241 31 solution solution NN cord-022526-j9kg00qf 241 32 as as IN cord-022526-j9kg00qf 241 33 contrast contrast NN cord-022526-j9kg00qf 241 34 material material NN cord-022526-j9kg00qf 241 35 . . . cord-022526-j9kg00qf 242 1 36 36 CD cord-022526-j9kg00qf 242 2 Contrast contrast NN cord-022526-j9kg00qf 242 3 radiography radiography NN cord-022526-j9kg00qf 242 4 may may MD cord-022526-j9kg00qf 242 5 be be VB cord-022526-j9kg00qf 242 6 the the DT cord-022526-j9kg00qf 242 7 most most RBS cord-022526-j9kg00qf 242 8 definitive definitive JJ cord-022526-j9kg00qf 242 9 method method NN cord-022526-j9kg00qf 242 10 for for IN cord-022526-j9kg00qf 242 11 the the DT cord-022526-j9kg00qf 242 12 diagnosis diagnosis NN cord-022526-j9kg00qf 242 13 of of IN cord-022526-j9kg00qf 242 14 primary primary JJ cord-022526-j9kg00qf 242 15 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 242 16 or or CC cord-022526-j9kg00qf 242 17 other other JJ cord-022526-j9kg00qf 242 18 functional functional JJ cord-022526-j9kg00qf 242 19 disorders disorder NNS cord-022526-j9kg00qf 242 20 such such JJ cord-022526-j9kg00qf 242 21 as as IN cord-022526-j9kg00qf 242 22 autonomic autonomic JJ cord-022526-j9kg00qf 242 23 dysautonomia dysautonomia NN cord-022526-j9kg00qf 242 24 ( ( -LRB- cord-022526-j9kg00qf 242 25 grass grass NN cord-022526-j9kg00qf 242 26 sickness sickness NN cord-022526-j9kg00qf 242 27 ) ) -RRB- cord-022526-j9kg00qf 242 28 affecting affect VBG cord-022526-j9kg00qf 242 29 the the DT cord-022526-j9kg00qf 242 30 esophagus esophagus NN cord-022526-j9kg00qf 242 31 . . . cord-022526-j9kg00qf 243 1 37 37 CD cord-022526-j9kg00qf 243 2 One one PRP cord-022526-j9kg00qf 243 3 should should MD cord-022526-j9kg00qf 243 4 take take VB cord-022526-j9kg00qf 243 5 care care NN cord-022526-j9kg00qf 243 6 when when WRB cord-022526-j9kg00qf 243 7 interpreting interpret VBG cord-022526-j9kg00qf 243 8 esophageal esophageal JJ cord-022526-j9kg00qf 243 9 radiographs radiograph NNS cord-022526-j9kg00qf 243 10 if if IN cord-022526-j9kg00qf 243 11 the the DT cord-022526-j9kg00qf 243 12 horse horse NN cord-022526-j9kg00qf 243 13 is be VBZ cord-022526-j9kg00qf 243 14 sedated sedate VBN cord-022526-j9kg00qf 243 15 . . . cord-022526-j9kg00qf 244 1 Acepromazine Acepromazine NNP cord-022526-j9kg00qf 244 2 or or CC cord-022526-j9kg00qf 244 3 detomidine detomidine NNP cord-022526-j9kg00qf 244 4 administration administration NN cord-022526-j9kg00qf 244 5 causes cause VBZ cord-022526-j9kg00qf 244 6 esophageal esophageal JJ cord-022526-j9kg00qf 244 7 dilation dilation NN cord-022526-j9kg00qf 244 8 in in IN cord-022526-j9kg00qf 244 9 normal normal JJ cord-022526-j9kg00qf 244 10 horses horse NNS cord-022526-j9kg00qf 244 11 , , , cord-022526-j9kg00qf 244 12 especially especially RB cord-022526-j9kg00qf 244 13 after after IN cord-022526-j9kg00qf 244 14 passage passage NN cord-022526-j9kg00qf 244 15 of of IN cord-022526-j9kg00qf 244 16 a a DT cord-022526-j9kg00qf 244 17 nasogastric nasogastric NN cord-022526-j9kg00qf 244 18 tube tube NN cord-022526-j9kg00qf 244 19 . . . cord-022526-j9kg00qf 245 1 38 38 CD cord-022526-j9kg00qf 245 2 Radiography radiography NN cord-022526-j9kg00qf 245 3 of of IN cord-022526-j9kg00qf 245 4 the the DT cord-022526-j9kg00qf 245 5 adult adult NN cord-022526-j9kg00qf 245 6 equine equine JJ cord-022526-j9kg00qf 245 7 abdomen abdomen NN cord-022526-j9kg00qf 245 8 is be VBZ cord-022526-j9kg00qf 245 9 an an DT cord-022526-j9kg00qf 245 10 effective effective JJ cord-022526-j9kg00qf 245 11 technique technique NN cord-022526-j9kg00qf 245 12 in in IN cord-022526-j9kg00qf 245 13 detecting detect VBG cord-022526-j9kg00qf 245 14 radiodense radiodense NN cord-022526-j9kg00qf 245 15 material material NN cord-022526-j9kg00qf 245 16 in in IN cord-022526-j9kg00qf 245 17 the the DT cord-022526-j9kg00qf 245 18 large large JJ cord-022526-j9kg00qf 245 19 intestine intestine NN cord-022526-j9kg00qf 245 20 , , , cord-022526-j9kg00qf 245 21 such such JJ cord-022526-j9kg00qf 245 22 as as IN cord-022526-j9kg00qf 245 23 enteroliths enterolith NNS cord-022526-j9kg00qf 245 24 , , , cord-022526-j9kg00qf 245 25 sand sand NN cord-022526-j9kg00qf 245 26 , , , cord-022526-j9kg00qf 245 27 and and CC cord-022526-j9kg00qf 245 28 metallic metallic JJ cord-022526-j9kg00qf 245 29 objects object NNS cord-022526-j9kg00qf 245 30 . . . cord-022526-j9kg00qf 246 1 39 39 CD cord-022526-j9kg00qf 246 2 , , , cord-022526-j9kg00qf 246 3 40 40 CD cord-022526-j9kg00qf 246 4 One one CD cord-022526-j9kg00qf 246 5 survey survey NN cord-022526-j9kg00qf 246 6 demonstrated demonstrate VBD cord-022526-j9kg00qf 246 7 that that IN cord-022526-j9kg00qf 246 8 radiography radiography NN cord-022526-j9kg00qf 246 9 has have VBZ cord-022526-j9kg00qf 246 10 76.9 76.9 CD cord-022526-j9kg00qf 246 11 % % NN cord-022526-j9kg00qf 246 12 sensitivity sensitivity NN cord-022526-j9kg00qf 246 13 and and CC cord-022526-j9kg00qf 246 14 94.4 94.4 CD cord-022526-j9kg00qf 246 15 % % NN cord-022526-j9kg00qf 246 16 specificity specificity NN cord-022526-j9kg00qf 246 17 for for IN cord-022526-j9kg00qf 246 18 diagnosing diagnose VBG cord-022526-j9kg00qf 246 19 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 246 20 . . . cord-022526-j9kg00qf 247 1 39 39 CD cord-022526-j9kg00qf 247 2 Radiography radiography NN cord-022526-j9kg00qf 247 3 also also RB cord-022526-j9kg00qf 247 4 can can MD cord-022526-j9kg00qf 247 5 be be VB cord-022526-j9kg00qf 247 6 a a DT cord-022526-j9kg00qf 247 7 useful useful JJ cord-022526-j9kg00qf 247 8 tool tool NN cord-022526-j9kg00qf 247 9 for for IN cord-022526-j9kg00qf 247 10 detecting detect VBG cord-022526-j9kg00qf 247 11 sand sand NN cord-022526-j9kg00qf 247 12 accumulation accumulation NN cord-022526-j9kg00qf 247 13 in in IN cord-022526-j9kg00qf 247 14 the the DT cord-022526-j9kg00qf 247 15 colon colon NN cord-022526-j9kg00qf 247 16 that that WDT cord-022526-j9kg00qf 247 17 causes cause VBZ cord-022526-j9kg00qf 247 18 diarrhea diarrhea NN cord-022526-j9kg00qf 247 19 or or CC cord-022526-j9kg00qf 247 20 impactions impaction NNS cord-022526-j9kg00qf 248 1 ( ( -LRB- cord-022526-j9kg00qf 248 2 Figure figure NN cord-022526-j9kg00qf 248 3 13 13 CD cord-022526-j9kg00qf 248 4 .1 .1 CD cord-022526-j9kg00qf 248 5 - - HYPH cord-022526-j9kg00qf 248 6 1 1 CD cord-022526-j9kg00qf 248 7 ) ) -RRB- cord-022526-j9kg00qf 249 1 and and CC cord-022526-j9kg00qf 249 2 for for IN cord-022526-j9kg00qf 249 3 monitoring monitor VBG cord-022526-j9kg00qf 249 4 resolution resolution NN cord-022526-j9kg00qf 249 5 in in IN cord-022526-j9kg00qf 249 6 medically medically RB cord-022526-j9kg00qf 249 7 treated treat VBN cord-022526-j9kg00qf 249 8 horses horse NNS cord-022526-j9kg00qf 249 9 . . . cord-022526-j9kg00qf 250 1 41 41 CD cord-022526-j9kg00qf 251 1 The the DT cord-022526-j9kg00qf 251 2 large large JJ cord-022526-j9kg00qf 251 3 size size NN cord-022526-j9kg00qf 251 4 and and CC cord-022526-j9kg00qf 251 5 density density NN cord-022526-j9kg00qf 251 6 of of IN cord-022526-j9kg00qf 251 7 the the DT cord-022526-j9kg00qf 251 8 adult adult NN cord-022526-j9kg00qf 251 9 abdomen abdomen NN cord-022526-j9kg00qf 251 10 precludes preclude VBZ cord-022526-j9kg00qf 251 11 evaluation evaluation NN cord-022526-j9kg00qf 251 12 of of IN cord-022526-j9kg00qf 251 13 soft soft JJ cord-022526-j9kg00qf 251 14 tissue tissue NN cord-022526-j9kg00qf 251 15 structures structure NNS cord-022526-j9kg00qf 251 16 because because IN cord-022526-j9kg00qf 251 17 the the DT cord-022526-j9kg00qf 251 18 detail detail NN cord-022526-j9kg00qf 251 19 and and CC cord-022526-j9kg00qf 251 20 contrast contrast NN cord-022526-j9kg00qf 251 21 of of IN cord-022526-j9kg00qf 251 22 the the DT cord-022526-j9kg00qf 251 23 radiographs radiograph NNS cord-022526-j9kg00qf 251 24 are be VBP cord-022526-j9kg00qf 251 25 usually usually RB cord-022526-j9kg00qf 251 26 poor poor JJ cord-022526-j9kg00qf 251 27 . . . cord-022526-j9kg00qf 252 1 One one CD cord-022526-j9kg00qf 252 2 is be VBZ cord-022526-j9kg00qf 252 3 more more RBR cord-022526-j9kg00qf 252 4 likely likely JJ cord-022526-j9kg00qf 252 5 to to TO cord-022526-j9kg00qf 252 6 obtain obtain VB cord-022526-j9kg00qf 252 7 diagnostically diagnostically RB cord-022526-j9kg00qf 252 8 useful useful JJ cord-022526-j9kg00qf 252 9 abdominal abdominal JJ cord-022526-j9kg00qf 252 10 radiographs radiograph NNS cord-022526-j9kg00qf 252 11 from from IN cord-022526-j9kg00qf 252 12 small small JJ cord-022526-j9kg00qf 252 13 ponies pony NNS cord-022526-j9kg00qf 252 14 and and CC cord-022526-j9kg00qf 252 15 miniature miniature JJ cord-022526-j9kg00qf 252 16 horses horse NNS cord-022526-j9kg00qf 252 17 than than IN cord-022526-j9kg00qf 252 18 from from IN cord-022526-j9kg00qf 252 19 full full JJ cord-022526-j9kg00qf 252 20 - - HYPH cord-022526-j9kg00qf 252 21 size size NN cord-022526-j9kg00qf 252 22 adult adult NN cord-022526-j9kg00qf 252 23 horses horse NNS cord-022526-j9kg00qf 252 24 . . . cord-022526-j9kg00qf 253 1 Accumulation accumulation NN cord-022526-j9kg00qf 253 2 of of IN cord-022526-j9kg00qf 253 3 gas gas NN cord-022526-j9kg00qf 253 4 is be VBZ cord-022526-j9kg00qf 253 5 visible visible JJ cord-022526-j9kg00qf 253 6 on on IN cord-022526-j9kg00qf 253 7 radiographs radiograph NNS cord-022526-j9kg00qf 253 8 of of IN cord-022526-j9kg00qf 253 9 adult adult NN cord-022526-j9kg00qf 253 10 horses horse NNS cord-022526-j9kg00qf 253 11 , , , cord-022526-j9kg00qf 253 12 but but CC cord-022526-j9kg00qf 253 13 distinguishing distinguish VBG cord-022526-j9kg00qf 253 14 normal normal JJ cord-022526-j9kg00qf 253 15 intestinal intestinal JJ cord-022526-j9kg00qf 253 16 gas gas NN cord-022526-j9kg00qf 253 17 from from IN cord-022526-j9kg00qf 253 18 obstruction obstruction NN cord-022526-j9kg00qf 253 19 is be VBZ cord-022526-j9kg00qf 253 20 often often RB cord-022526-j9kg00qf 253 21 difficult difficult JJ cord-022526-j9kg00qf 253 22 . . . cord-022526-j9kg00qf 254 1 Horses horse NNS cord-022526-j9kg00qf 254 2 should should MD cord-022526-j9kg00qf 254 3 be be VB cord-022526-j9kg00qf 254 4 fasted fast VBN cord-022526-j9kg00qf 254 5 for for IN cord-022526-j9kg00qf 254 6 24 24 CD cord-022526-j9kg00qf 254 7 to to TO cord-022526-j9kg00qf 254 8 48 48 CD cord-022526-j9kg00qf 254 9 hours hour NNS cord-022526-j9kg00qf 254 10 to to TO cord-022526-j9kg00qf 254 11 reduce reduce VB cord-022526-j9kg00qf 254 12 the the DT cord-022526-j9kg00qf 254 13 amount amount NN cord-022526-j9kg00qf 254 14 of of IN cord-022526-j9kg00qf 254 15 ingesta ingesta NNS cord-022526-j9kg00qf 254 16 in in IN cord-022526-j9kg00qf 254 17 the the DT cord-022526-j9kg00qf 254 18 large large JJ cord-022526-j9kg00qf 254 19 intestine intestine NN cord-022526-j9kg00qf 254 20 before before IN cord-022526-j9kg00qf 254 21 radiography radiography NN cord-022526-j9kg00qf 254 22 . . . cord-022526-j9kg00qf 255 1 Abdominal abdominal JJ cord-022526-j9kg00qf 255 2 radiography radiography NN cord-022526-j9kg00qf 255 3 is be VBZ cord-022526-j9kg00qf 255 4 more more RBR cord-022526-j9kg00qf 255 5 useful useful JJ cord-022526-j9kg00qf 255 6 in in IN cord-022526-j9kg00qf 255 7 foals foal NNS cord-022526-j9kg00qf 255 8 than than IN cord-022526-j9kg00qf 255 9 in in IN cord-022526-j9kg00qf 255 10 adult adult NN cord-022526-j9kg00qf 255 11 horses horse NNS cord-022526-j9kg00qf 255 12 . . . cord-022526-j9kg00qf 256 1 Radiographs radiograph NNS cord-022526-j9kg00qf 256 2 are be VBP cord-022526-j9kg00qf 256 3 more more RBR cord-022526-j9kg00qf 256 4 detailed detailed JJ cord-022526-j9kg00qf 256 5 and and CC cord-022526-j9kg00qf 256 6 contrast contrast NN cord-022526-j9kg00qf 256 7 can can MD cord-022526-j9kg00qf 256 8 be be VB cord-022526-j9kg00qf 256 9 good good JJ cord-022526-j9kg00qf 256 10 . . . cord-022526-j9kg00qf 257 1 Radiographic radiographic JJ cord-022526-j9kg00qf 257 2 evidence evidence NN cord-022526-j9kg00qf 257 3 of of IN cord-022526-j9kg00qf 257 4 gas gas NN cord-022526-j9kg00qf 257 5 distention distention NN cord-022526-j9kg00qf 257 6 in in IN cord-022526-j9kg00qf 257 7 the the DT cord-022526-j9kg00qf 257 8 large large JJ cord-022526-j9kg00qf 257 9 intestine intestine NN cord-022526-j9kg00qf 257 10 may may MD cord-022526-j9kg00qf 257 11 indicate indicate VB cord-022526-j9kg00qf 257 12 large large JJ cord-022526-j9kg00qf 257 13 intestinal intestinal JJ cord-022526-j9kg00qf 257 14 obstruction obstruction NN cord-022526-j9kg00qf 257 15 , , , cord-022526-j9kg00qf 257 16 and and CC cord-022526-j9kg00qf 257 17 radiographic radiographic JJ cord-022526-j9kg00qf 257 18 signs sign NNS cord-022526-j9kg00qf 257 19 of of IN cord-022526-j9kg00qf 257 20 displacement displacement NN cord-022526-j9kg00qf 257 21 are be VBP cord-022526-j9kg00qf 257 22 often often RB cord-022526-j9kg00qf 257 23 diagnostic diagnostic JJ cord-022526-j9kg00qf 257 24 . . . cord-022526-j9kg00qf 258 1 One one CD cord-022526-j9kg00qf 258 2 may may MD cord-022526-j9kg00qf 258 3 diagnose diagnose VB cord-022526-j9kg00qf 258 4 impactions impaction NNS cord-022526-j9kg00qf 258 5 , , , cord-022526-j9kg00qf 258 6 intussusceptions intussusception NNS cord-022526-j9kg00qf 258 7 , , , cord-022526-j9kg00qf 258 8 foreign foreign JJ cord-022526-j9kg00qf 258 9 bodies body NNS cord-022526-j9kg00qf 258 10 , , , cord-022526-j9kg00qf 258 11 and and CC cord-022526-j9kg00qf 258 12 other other JJ cord-022526-j9kg00qf 258 13 disorders disorder NNS cord-022526-j9kg00qf 258 14 with with IN cord-022526-j9kg00qf 258 15 the the DT cord-022526-j9kg00qf 258 16 aid aid NN cord-022526-j9kg00qf 258 17 of of IN cord-022526-j9kg00qf 258 18 radiography radiography NN cord-022526-j9kg00qf 258 19 . . . cord-022526-j9kg00qf 259 1 Functional functional JJ cord-022526-j9kg00qf 259 2 ileus ileus NN cord-022526-j9kg00qf 259 3 may may MD cord-022526-j9kg00qf 259 4 be be VB cord-022526-j9kg00qf 259 5 difficult difficult JJ cord-022526-j9kg00qf 259 6 to to TO cord-022526-j9kg00qf 259 7 distinguish distinguish VB cord-022526-j9kg00qf 259 8 from from IN cord-022526-j9kg00qf 259 9 mechanical mechanical JJ cord-022526-j9kg00qf 259 10 obstruction obstruction NN cord-022526-j9kg00qf 259 11 . . . cord-022526-j9kg00qf 260 1 42 42 CD cord-022526-j9kg00qf 260 2 , , , cord-022526-j9kg00qf 260 3 43 43 CD cord-022526-j9kg00qf 260 4 Administration Administration NNP cord-022526-j9kg00qf 260 5 of of IN cord-022526-j9kg00qf 260 6 contrast contrast NN cord-022526-j9kg00qf 260 7 ( ( -LRB- cord-022526-j9kg00qf 260 8 barium barium NN cord-022526-j9kg00qf 260 9 sulfate sulfate NN cord-022526-j9kg00qf 260 10 30 30 CD cord-022526-j9kg00qf 260 11 % % NN cord-022526-j9kg00qf 260 12 at at IN cord-022526-j9kg00qf 260 13 5 5 CD cord-022526-j9kg00qf 260 14 ml ml NN cord-022526-j9kg00qf 260 15 / / SYM cord-022526-j9kg00qf 260 16 kg kg NN cord-022526-j9kg00qf 260 17 ) ) -RRB- cord-022526-j9kg00qf 260 18 via via IN cord-022526-j9kg00qf 260 19 nasogastric nasogastric NN cord-022526-j9kg00qf 260 20 tube tube NN cord-022526-j9kg00qf 260 21 increases increase VBZ cord-022526-j9kg00qf 260 22 the the DT cord-022526-j9kg00qf 260 23 diagnostic diagnostic JJ cord-022526-j9kg00qf 260 24 capabilities capability NNS cord-022526-j9kg00qf 260 25 of of IN cord-022526-j9kg00qf 260 26 radiography radiography NN cord-022526-j9kg00qf 260 27 . . . cord-022526-j9kg00qf 261 1 44 44 CD cord-022526-j9kg00qf 261 2 Gastric gastric JJ cord-022526-j9kg00qf 261 3 ulceration ulceration NN cord-022526-j9kg00qf 261 4 also also RB cord-022526-j9kg00qf 261 5 is be VBZ cord-022526-j9kg00qf 261 6 recognizable recognizable JJ cord-022526-j9kg00qf 261 7 with with IN cord-022526-j9kg00qf 261 8 contrast contrast NN cord-022526-j9kg00qf 261 9 radiography radiography NN cord-022526-j9kg00qf 261 10 in in IN cord-022526-j9kg00qf 261 11 the the DT cord-022526-j9kg00qf 261 12 foal foal NN cord-022526-j9kg00qf 261 13 , , , cord-022526-j9kg00qf 261 14 although although IN cord-022526-j9kg00qf 261 15 this this DT cord-022526-j9kg00qf 261 16 is be VBZ cord-022526-j9kg00qf 261 17 not not RB cord-022526-j9kg00qf 261 18 as as RB cord-022526-j9kg00qf 261 19 accurate accurate JJ cord-022526-j9kg00qf 261 20 a a DT cord-022526-j9kg00qf 261 21 method method NN cord-022526-j9kg00qf 261 22 as as IN cord-022526-j9kg00qf 261 23 endoscopy endoscopy NN cord-022526-j9kg00qf 261 24 . . . cord-022526-j9kg00qf 262 1 45 45 CD cord-022526-j9kg00qf 263 1 Contrast contrast NN cord-022526-j9kg00qf 263 2 administered administer VBN cord-022526-j9kg00qf 263 3 retrograde retrograde JJ cord-022526-j9kg00qf 263 4 via via IN cord-022526-j9kg00qf 263 5 a a DT cord-022526-j9kg00qf 263 6 24-F 24-f JJ cord-022526-j9kg00qf 263 7 Foley Foley NNP cord-022526-j9kg00qf 263 8 catheter catheter NN cord-022526-j9kg00qf 263 9 inserted insert VBN cord-022526-j9kg00qf 263 10 into into IN cord-022526-j9kg00qf 263 11 the the DT cord-022526-j9kg00qf 263 12 rectum rectum NN cord-022526-j9kg00qf 263 13 at at IN cord-022526-j9kg00qf 263 14 a a DT cord-022526-j9kg00qf 263 15 dose dose NN cord-022526-j9kg00qf 263 16 of of IN cord-022526-j9kg00qf 263 17 up up IN cord-022526-j9kg00qf 263 18 to to TO cord-022526-j9kg00qf 263 19 20 20 CD cord-022526-j9kg00qf 263 20 ml ml NNS cord-022526-j9kg00qf 263 21 / / SYM cord-022526-j9kg00qf 263 22 kg kg NN cord-022526-j9kg00qf 264 1 has have VBZ cord-022526-j9kg00qf 264 2 excellent excellent JJ cord-022526-j9kg00qf 264 3 potential potential NN cord-022526-j9kg00qf 264 4 for for IN cord-022526-j9kg00qf 264 5 diagnosing diagnose VBG cord-022526-j9kg00qf 264 6 disorders disorder NNS cord-022526-j9kg00qf 264 7 of of IN cord-022526-j9kg00qf 264 8 the the DT cord-022526-j9kg00qf 264 9 small small JJ cord-022526-j9kg00qf 264 10 colon colon NN cord-022526-j9kg00qf 264 11 , , , cord-022526-j9kg00qf 264 12 transverse transverse JJ cord-022526-j9kg00qf 264 13 colon colon NN cord-022526-j9kg00qf 264 14 , , , cord-022526-j9kg00qf 264 15 and and CC cord-022526-j9kg00qf 264 16 large large JJ cord-022526-j9kg00qf 264 17 colon colon NN cord-022526-j9kg00qf 264 18 in in IN cord-022526-j9kg00qf 264 19 foals foal NNS cord-022526-j9kg00qf 264 20 . . . cord-022526-j9kg00qf 265 1 46 46 CD cord-022526-j9kg00qf 265 2 _SP cord-022526-j9kg00qf 266 1 Ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 266 2 evaluation evaluation NN cord-022526-j9kg00qf 266 3 of of IN cord-022526-j9kg00qf 266 4 the the DT cord-022526-j9kg00qf 266 5 abdomen abdomen NN cord-022526-j9kg00qf 266 6 can can MD cord-022526-j9kg00qf 266 7 add add VB cord-022526-j9kg00qf 266 8 valuable valuable JJ cord-022526-j9kg00qf 266 9 information information NN cord-022526-j9kg00qf 266 10 in in IN cord-022526-j9kg00qf 266 11 cases case NNS cord-022526-j9kg00qf 266 12 of of IN cord-022526-j9kg00qf 266 13 acute acute JJ cord-022526-j9kg00qf 266 14 or or CC cord-022526-j9kg00qf 266 15 chronic chronic JJ cord-022526-j9kg00qf 266 16 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 266 17 disease disease NN cord-022526-j9kg00qf 266 18 . . . cord-022526-j9kg00qf 267 1 Examination examination NN cord-022526-j9kg00qf 267 2 of of IN cord-022526-j9kg00qf 267 3 the the DT cord-022526-j9kg00qf 267 4 adult adult NN cord-022526-j9kg00qf 267 5 horse horse NN cord-022526-j9kg00qf 267 6 requires require VBZ cord-022526-j9kg00qf 267 7 a a DT cord-022526-j9kg00qf 267 8 2.5-to 2.5-to CD cord-022526-j9kg00qf 267 9 5.0-MHz 5.0-mhz CD cord-022526-j9kg00qf 267 10 transducer transducer NN cord-022526-j9kg00qf 267 11 at at IN cord-022526-j9kg00qf 267 12 minimum minimum NN cord-022526-j9kg00qf 267 13 . . . cord-022526-j9kg00qf 268 1 One one CD cord-022526-j9kg00qf 268 2 may may MD cord-022526-j9kg00qf 268 3 use use VB cord-022526-j9kg00qf 268 4 sector sector NN cord-022526-j9kg00qf 268 5 , , , cord-022526-j9kg00qf 268 6 linear linear NNP cord-022526-j9kg00qf 268 7 , , , cord-022526-j9kg00qf 268 8 or or CC cord-022526-j9kg00qf 268 9 curved curved JJ cord-022526-j9kg00qf 268 10 linear linear JJ cord-022526-j9kg00qf 268 11 transducers transducer NNS cord-022526-j9kg00qf 268 12 . . . cord-022526-j9kg00qf 269 1 Clipping clip VBG cord-022526-j9kg00qf 269 2 of of IN cord-022526-j9kg00qf 269 3 the the DT cord-022526-j9kg00qf 269 4 hair hair NN cord-022526-j9kg00qf 269 5 over over IN cord-022526-j9kg00qf 269 6 the the DT cord-022526-j9kg00qf 269 7 area area NN cord-022526-j9kg00qf 269 8 to to TO cord-022526-j9kg00qf 269 9 be be VB cord-022526-j9kg00qf 269 10 examined examine VBN cord-022526-j9kg00qf 269 11 , , , cord-022526-j9kg00qf 269 12 along along IN cord-022526-j9kg00qf 269 13 with with IN cord-022526-j9kg00qf 269 14 the the DT cord-022526-j9kg00qf 269 15 application application NN cord-022526-j9kg00qf 269 16 of of IN cord-022526-j9kg00qf 269 17 isopropyl isopropyl NN cord-022526-j9kg00qf 269 18 alcohol alcohol NN cord-022526-j9kg00qf 269 19 and and CC cord-022526-j9kg00qf 269 20 ultrasound ultrasound NN cord-022526-j9kg00qf 269 21 coupling coupling NN cord-022526-j9kg00qf 269 22 gel gel NN cord-022526-j9kg00qf 269 23 , , , cord-022526-j9kg00qf 269 24 enhances enhance VBZ cord-022526-j9kg00qf 269 25 evaluation evaluation NN cord-022526-j9kg00qf 269 26 . . . cord-022526-j9kg00qf 270 1 To to TO cord-022526-j9kg00qf 270 2 evaluate evaluate VB cord-022526-j9kg00qf 270 3 the the DT cord-022526-j9kg00qf 270 4 abdomen abdomen NN cord-022526-j9kg00qf 270 5 adequately adequately RB cord-022526-j9kg00qf 270 6 , , , cord-022526-j9kg00qf 270 7 one one PRP cord-022526-j9kg00qf 270 8 must must MD cord-022526-j9kg00qf 270 9 know know VB cord-022526-j9kg00qf 270 10 the the DT cord-022526-j9kg00qf 270 11 anatomic anatomic JJ cord-022526-j9kg00qf 270 12 location location NN cord-022526-j9kg00qf 270 13 and and CC cord-022526-j9kg00qf 270 14 normal normal JJ cord-022526-j9kg00qf 270 15 appearance appearance NN cord-022526-j9kg00qf 270 16 of of IN cord-022526-j9kg00qf 270 17 the the DT cord-022526-j9kg00qf 270 18 individual individual JJ cord-022526-j9kg00qf 270 19 organs organ NNS cord-022526-j9kg00qf 270 20 . . . cord-022526-j9kg00qf 271 1 In in IN cord-022526-j9kg00qf 271 2 the the DT cord-022526-j9kg00qf 271 3 left left JJ cord-022526-j9kg00qf 271 4 cranial cranial JJ cord-022526-j9kg00qf 271 5 abdomen abdomen NN cord-022526-j9kg00qf 271 6 , , , cord-022526-j9kg00qf 271 7 one one PRP cord-022526-j9kg00qf 271 8 can can MD cord-022526-j9kg00qf 271 9 assess assess VB cord-022526-j9kg00qf 271 10 the the DT cord-022526-j9kg00qf 271 11 greater great JJR cord-022526-j9kg00qf 271 12 curvature curvature NN cord-022526-j9kg00qf 271 13 of of IN cord-022526-j9kg00qf 271 14 the the DT cord-022526-j9kg00qf 271 15 stomach stomach NN cord-022526-j9kg00qf 271 16 between between IN cord-022526-j9kg00qf 271 17 the the DT cord-022526-j9kg00qf 271 18 eleventh eleventh JJ cord-022526-j9kg00qf 271 19 and and CC cord-022526-j9kg00qf 271 20 thirteenth thirteenth JJ cord-022526-j9kg00qf 271 21 intercostal intercostal JJ cord-022526-j9kg00qf 271 22 space space NN cord-022526-j9kg00qf 271 23 , , , cord-022526-j9kg00qf 271 24 and and CC cord-022526-j9kg00qf 271 25 one one PRP cord-022526-j9kg00qf 271 26 can can MD cord-022526-j9kg00qf 271 27 use use VB cord-022526-j9kg00qf 271 28 the the DT cord-022526-j9kg00qf 271 29 spleen spleen NN cord-022526-j9kg00qf 271 30 and and CC cord-022526-j9kg00qf 271 31 the the DT cord-022526-j9kg00qf 271 32 large large JJ cord-022526-j9kg00qf 271 33 splenic splenic JJ cord-022526-j9kg00qf 271 34 vein vein NN cord-022526-j9kg00qf 271 35 as as IN cord-022526-j9kg00qf 271 36 landmarks landmark NNS cord-022526-j9kg00qf 271 37 . . . cord-022526-j9kg00qf 272 1 Cases case NNS cord-022526-j9kg00qf 272 2 of of IN cord-022526-j9kg00qf 272 3 gastric gastric JJ cord-022526-j9kg00qf 272 4 dilation dilation NN cord-022526-j9kg00qf 272 5 from from IN cord-022526-j9kg00qf 272 6 gas gas NN cord-022526-j9kg00qf 272 7 or or CC cord-022526-j9kg00qf 272 8 impaction impaction NN cord-022526-j9kg00qf 272 9 appear appear VB cord-022526-j9kg00qf 272 10 as as IN cord-022526-j9kg00qf 272 11 an an DT cord-022526-j9kg00qf 272 12 enlargement enlargement NN cord-022526-j9kg00qf 272 13 of of IN cord-022526-j9kg00qf 272 14 the the DT cord-022526-j9kg00qf 272 15 viewing viewing NN cord-022526-j9kg00qf 272 16 area area NN cord-022526-j9kg00qf 272 17 to to TO cord-022526-j9kg00qf 272 18 cover cover VB cord-022526-j9kg00qf 272 19 greater great JJR cord-022526-j9kg00qf 272 20 than than IN cord-022526-j9kg00qf 272 21 five five CD cord-022526-j9kg00qf 272 22 rib rib NN cord-022526-j9kg00qf 272 23 spaces space NNS cord-022526-j9kg00qf 272 24 . . . cord-022526-j9kg00qf 273 1 47 47 CD cord-022526-j9kg00qf 274 1 One one CD cord-022526-j9kg00qf 274 2 also also RB cord-022526-j9kg00qf 274 3 can can MD cord-022526-j9kg00qf 274 4 evaluate evaluate VB cord-022526-j9kg00qf 274 5 the the DT cord-022526-j9kg00qf 274 6 stomach stomach NN cord-022526-j9kg00qf 274 7 for for IN cord-022526-j9kg00qf 274 8 intramural intramural JJ cord-022526-j9kg00qf 274 9 or or CC cord-022526-j9kg00qf 274 10 extramural extramural JJ cord-022526-j9kg00qf 274 11 masses masse NNS cord-022526-j9kg00qf 274 12 such such JJ cord-022526-j9kg00qf 274 13 as as IN cord-022526-j9kg00qf 274 14 abscesses abscess NNS cord-022526-j9kg00qf 274 15 or or CC cord-022526-j9kg00qf 274 16 for for IN cord-022526-j9kg00qf 274 17 squamous squamous JJ cord-022526-j9kg00qf 274 18 cell cell NN cord-022526-j9kg00qf 274 19 carcinoma carcinoma NN cord-022526-j9kg00qf 274 20 . . . cord-022526-j9kg00qf 275 1 48 48 CD cord-022526-j9kg00qf 276 1 The the DT cord-022526-j9kg00qf 276 2 lesser less JJR cord-022526-j9kg00qf 276 3 curvature curvature NN cord-022526-j9kg00qf 276 4 is be VBZ cord-022526-j9kg00qf 276 5 not not RB cord-022526-j9kg00qf 276 6 routinely routinely RB cord-022526-j9kg00qf 276 7 visible visible JJ cord-022526-j9kg00qf 276 8 . . . cord-022526-j9kg00qf 277 1 Assessment assessment NN cord-022526-j9kg00qf 277 2 of of IN cord-022526-j9kg00qf 277 3 the the DT cord-022526-j9kg00qf 277 4 small small JJ cord-022526-j9kg00qf 277 5 intestine intestine NN cord-022526-j9kg00qf 277 6 should should MD cord-022526-j9kg00qf 277 7 include include VB cord-022526-j9kg00qf 277 8 evaluation evaluation NN cord-022526-j9kg00qf 277 9 for for IN cord-022526-j9kg00qf 277 10 changes change NNS cord-022526-j9kg00qf 277 11 in in IN cord-022526-j9kg00qf 277 12 thickness thickness NN cord-022526-j9kg00qf 277 13 , , , cord-022526-j9kg00qf 277 14 motility motility NN cord-022526-j9kg00qf 277 15 , , , cord-022526-j9kg00qf 277 16 location location NN cord-022526-j9kg00qf 277 17 , , , cord-022526-j9kg00qf 277 18 and and CC cord-022526-j9kg00qf 277 19 visibility visibility NN cord-022526-j9kg00qf 277 20 . . . cord-022526-j9kg00qf 278 1 One one PRP cord-022526-j9kg00qf 278 2 may may MD cord-022526-j9kg00qf 278 3 find find VB cord-022526-j9kg00qf 278 4 small small JJ cord-022526-j9kg00qf 278 5 intestinal intestinal JJ cord-022526-j9kg00qf 278 6 loops loop NNS cord-022526-j9kg00qf 278 7 easily easily RB cord-022526-j9kg00qf 278 8 in in IN cord-022526-j9kg00qf 278 9 the the DT cord-022526-j9kg00qf 278 10 left left JJ cord-022526-j9kg00qf 278 11 lower low JJR cord-022526-j9kg00qf 278 12 quadrant quadrant NN cord-022526-j9kg00qf 278 13 of of IN cord-022526-j9kg00qf 278 14 the the DT cord-022526-j9kg00qf 278 15 abdomen abdomen NN cord-022526-j9kg00qf 278 16 , , , cord-022526-j9kg00qf 278 17 but but CC cord-022526-j9kg00qf 278 18 these these DT cord-022526-j9kg00qf 278 19 normally normally RB cord-022526-j9kg00qf 278 20 are be VBP cord-022526-j9kg00qf 278 21 visible visible JJ cord-022526-j9kg00qf 278 22 in in IN cord-022526-j9kg00qf 278 23 other other JJ cord-022526-j9kg00qf 278 24 locations location NNS cord-022526-j9kg00qf 278 25 . . . cord-022526-j9kg00qf 279 1 One one PRP cord-022526-j9kg00qf 279 2 can can MD cord-022526-j9kg00qf 279 3 visualize visualize VB cord-022526-j9kg00qf 279 4 the the DT cord-022526-j9kg00qf 279 5 duodenum duodenum NN cord-022526-j9kg00qf 279 6 consistently consistently RB cord-022526-j9kg00qf 279 7 on on IN cord-022526-j9kg00qf 279 8 the the DT cord-022526-j9kg00qf 279 9 right right JJ cord-022526-j9kg00qf 279 10 side side NN cord-022526-j9kg00qf 279 11 of of IN cord-022526-j9kg00qf 279 12 the the DT cord-022526-j9kg00qf 279 13 abdomen abdomen NN cord-022526-j9kg00qf 279 14 deep deep RB cord-022526-j9kg00qf 279 15 to to IN cord-022526-j9kg00qf 279 16 the the DT cord-022526-j9kg00qf 279 17 liver liver NN cord-022526-j9kg00qf 279 18 in in IN cord-022526-j9kg00qf 279 19 the the DT cord-022526-j9kg00qf 279 20 tenth tenth JJ cord-022526-j9kg00qf 279 21 to to IN cord-022526-j9kg00qf 279 22 twelfth twelfth JJ cord-022526-j9kg00qf 279 23 intercostal intercostal JJ cord-022526-j9kg00qf 279 24 space space NN cord-022526-j9kg00qf 279 25 or or CC cord-022526-j9kg00qf 279 26 deep deep JJ cord-022526-j9kg00qf 279 27 to to IN cord-022526-j9kg00qf 279 28 the the DT cord-022526-j9kg00qf 279 29 right right JJ cord-022526-j9kg00qf 279 30 kidney kidney NN cord-022526-j9kg00qf 279 31 at at IN cord-022526-j9kg00qf 279 32 the the DT cord-022526-j9kg00qf 279 33 fifteenth fifteenth NN cord-022526-j9kg00qf 279 34 to to IN cord-022526-j9kg00qf 279 35 sixteenth sixteenth JJ cord-022526-j9kg00qf 279 36 intercostal intercostal JJ cord-022526-j9kg00qf 279 37 space space NN cord-022526-j9kg00qf 279 38 . . . cord-022526-j9kg00qf 280 1 Mural mural NN cord-022526-j9kg00qf 280 2 thickening thickening NN cord-022526-j9kg00qf 280 3 ( ( -LRB- cord-022526-j9kg00qf 280 4 > > NFP cord-022526-j9kg00qf 280 5 4 4 CD cord-022526-j9kg00qf 280 6 mm mm NNP cord-022526-j9kg00qf 280 7 ) ) -RRB- cord-022526-j9kg00qf 280 8 may may MD cord-022526-j9kg00qf 280 9 occur occur VB cord-022526-j9kg00qf 280 10 in in IN cord-022526-j9kg00qf 280 11 cases case NNS cord-022526-j9kg00qf 280 12 of of IN cord-022526-j9kg00qf 280 13 infiltrative infiltrative JJ cord-022526-j9kg00qf 280 14 or or CC cord-022526-j9kg00qf 280 15 proliferative proliferative JJ cord-022526-j9kg00qf 280 16 diseases disease NNS cord-022526-j9kg00qf 280 17 , , , cord-022526-j9kg00qf 280 18 postoperative postoperative JJ cord-022526-j9kg00qf 280 19 cases case NNS cord-022526-j9kg00qf 280 20 , , , cord-022526-j9kg00qf 280 21 enteritis enteritis NN cord-022526-j9kg00qf 280 22 , , , cord-022526-j9kg00qf 280 23 and and CC cord-022526-j9kg00qf 280 24 paralytic paralytic JJ cord-022526-j9kg00qf 280 25 or or CC cord-022526-j9kg00qf 280 26 mechanical mechanical JJ cord-022526-j9kg00qf 280 27 ileus ileus NN cord-022526-j9kg00qf 280 28 . . . cord-022526-j9kg00qf 281 1 Thickening thickening NN cord-022526-j9kg00qf 281 2 of of IN cord-022526-j9kg00qf 281 3 the the DT cord-022526-j9kg00qf 281 4 small small JJ cord-022526-j9kg00qf 281 5 intestinal intestinal JJ cord-022526-j9kg00qf 281 6 wall wall NN cord-022526-j9kg00qf 281 7 in in IN cord-022526-j9kg00qf 281 8 foals foal NNS cord-022526-j9kg00qf 281 9 , , , cord-022526-j9kg00qf 281 10 with with IN cord-022526-j9kg00qf 281 11 or or CC cord-022526-j9kg00qf 281 12 without without IN cord-022526-j9kg00qf 281 13 the the DT cord-022526-j9kg00qf 281 14 presence presence NN cord-022526-j9kg00qf 281 15 of of IN cord-022526-j9kg00qf 281 16 gas gas NN cord-022526-j9kg00qf 281 17 shadows shadow NNS cord-022526-j9kg00qf 281 18 within within IN cord-022526-j9kg00qf 281 19 the the DT cord-022526-j9kg00qf 281 20 wall wall NN cord-022526-j9kg00qf 281 21 , , , cord-022526-j9kg00qf 281 22 should should MD cord-022526-j9kg00qf 281 23 raise raise VB cord-022526-j9kg00qf 281 24 suspicions suspicion NNS cord-022526-j9kg00qf 281 25 of of IN cord-022526-j9kg00qf 281 26 clostridial clostridial JJ cord-022526-j9kg00qf 281 27 enteritis enteritis NN cord-022526-j9kg00qf 281 28 . . . cord-022526-j9kg00qf 282 1 One one PRP cord-022526-j9kg00qf 282 2 can can MD cord-022526-j9kg00qf 282 3 assess assess VB cord-022526-j9kg00qf 282 4 motility motility NN cord-022526-j9kg00qf 282 5 by by IN cord-022526-j9kg00qf 282 6 monitoring monitor VBG cord-022526-j9kg00qf 282 7 a a DT cord-022526-j9kg00qf 282 8 specific specific JJ cord-022526-j9kg00qf 282 9 area area NN cord-022526-j9kg00qf 282 10 for for IN cord-022526-j9kg00qf 282 11 contractions contraction NNS cord-022526-j9kg00qf 282 12 over over IN cord-022526-j9kg00qf 282 13 time time NN cord-022526-j9kg00qf 282 14 . . . cord-022526-j9kg00qf 283 1 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 283 2 is be VBZ cord-022526-j9kg00qf 283 3 an an DT cord-022526-j9kg00qf 283 4 accurate accurate JJ cord-022526-j9kg00qf 283 5 method method NN cord-022526-j9kg00qf 283 6 of of IN cord-022526-j9kg00qf 283 7 distinguishing distinguish VBG cord-022526-j9kg00qf 283 8 strangulating strangulating JJ cord-022526-j9kg00qf 283 9 versus versus IN cord-022526-j9kg00qf 283 10 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 283 11 disorders disorder NNS cord-022526-j9kg00qf 283 12 of of IN cord-022526-j9kg00qf 283 13 the the DT cord-022526-j9kg00qf 283 14 small small JJ cord-022526-j9kg00qf 283 15 intestine intestine NN cord-022526-j9kg00qf 283 16 . . . cord-022526-j9kg00qf 284 1 Strangulated strangulated JJ cord-022526-j9kg00qf 284 2 small small JJ cord-022526-j9kg00qf 284 3 intestine intestine NN cord-022526-j9kg00qf 284 4 has have VBZ cord-022526-j9kg00qf 284 5 thicker thick JJR cord-022526-j9kg00qf 284 6 small small JJ cord-022526-j9kg00qf 284 7 intestinal intestinal JJ cord-022526-j9kg00qf 284 8 walls wall NNS cord-022526-j9kg00qf 284 9 and and CC cord-022526-j9kg00qf 284 10 larger large JJR cord-022526-j9kg00qf 284 11 intestinal intestinal JJ cord-022526-j9kg00qf 284 12 diameter diameter NN cord-022526-j9kg00qf 284 13 than than IN cord-022526-j9kg00qf 284 14 in in IN cord-022526-j9kg00qf 284 15 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 284 16 disorders disorder NNS cord-022526-j9kg00qf 284 17 . . . cord-022526-j9kg00qf 285 1 Strangulating strangulating JJ cord-022526-j9kg00qf 285 2 lesions lesion NNS cord-022526-j9kg00qf 285 3 have have VBP cord-022526-j9kg00qf 285 4 decreased decrease VBN cord-022526-j9kg00qf 285 5 motility motility NN cord-022526-j9kg00qf 285 6 in in IN cord-022526-j9kg00qf 285 7 the the DT cord-022526-j9kg00qf 285 8 incarcerated incarcerate VBN cord-022526-j9kg00qf 285 9 segments segment NNS cord-022526-j9kg00qf 285 10 with with IN cord-022526-j9kg00qf 285 11 normal normal JJ cord-022526-j9kg00qf 285 12 motility motility NN cord-022526-j9kg00qf 285 13 elsewhere elsewhere RB cord-022526-j9kg00qf 285 14 . . . cord-022526-j9kg00qf 286 1 49 49 CD cord-022526-j9kg00qf 286 2 Cases case NNS cord-022526-j9kg00qf 286 3 of of IN cord-022526-j9kg00qf 286 4 paralytic paralytic JJ cord-022526-j9kg00qf 286 5 ileus ileus NN cord-022526-j9kg00qf 286 6 or or CC cord-022526-j9kg00qf 286 7 nonstrangulating nonstrangulating NN cord-022526-j9kg00qf 286 8 obstruction obstruction NN cord-022526-j9kg00qf 286 9 have have VBP cord-022526-j9kg00qf 286 10 a a DT cord-022526-j9kg00qf 286 11 diffusely diffusely RB cord-022526-j9kg00qf 286 12 decreased decrease VBN cord-022526-j9kg00qf 286 13 peristalsis peristalsis NN cord-022526-j9kg00qf 286 14 , , , cord-022526-j9kg00qf 286 15 but but CC cord-022526-j9kg00qf 286 16 not not RB cord-022526-j9kg00qf 286 17 to to IN cord-022526-j9kg00qf 286 18 the the DT cord-022526-j9kg00qf 286 19 degree degree NN cord-022526-j9kg00qf 286 20 observed observe VBN cord-022526-j9kg00qf 286 21 with with IN cord-022526-j9kg00qf 286 22 strangulating strangulating JJ cord-022526-j9kg00qf 286 23 lesions lesion NNS cord-022526-j9kg00qf 286 24 . . . cord-022526-j9kg00qf 287 1 47 47 CD cord-022526-j9kg00qf 287 2 , , , cord-022526-j9kg00qf 287 3 49 49 CD cord-022526-j9kg00qf 287 4 One one CD cord-022526-j9kg00qf 287 5 may may MD cord-022526-j9kg00qf 287 6 diagnose diagnose VB cord-022526-j9kg00qf 287 7 some some DT cord-022526-j9kg00qf 287 8 specific specific JJ cord-022526-j9kg00qf 287 9 lesions lesion NNS cord-022526-j9kg00qf 287 10 of of IN cord-022526-j9kg00qf 287 11 the the DT cord-022526-j9kg00qf 287 12 small small JJ cord-022526-j9kg00qf 287 13 intestinal intestinal JJ cord-022526-j9kg00qf 287 14 tract tract NN cord-022526-j9kg00qf 287 15 using use VBG cord-022526-j9kg00qf 287 16 ultrasonography ultrasonography NN cord-022526-j9kg00qf 287 17 . . . cord-022526-j9kg00qf 288 1 One one CD cord-022526-j9kg00qf 288 2 may may MD cord-022526-j9kg00qf 288 3 see see VB cord-022526-j9kg00qf 288 4 ascarids ascarid NNS cord-022526-j9kg00qf 288 5 in in IN cord-022526-j9kg00qf 288 6 foals foal NNS cord-022526-j9kg00qf 288 7 in in IN cord-022526-j9kg00qf 288 8 cases case NNS cord-022526-j9kg00qf 288 9 of of IN cord-022526-j9kg00qf 288 10 ascarid ascarid JJ cord-022526-j9kg00qf 288 11 impaction impaction NN cord-022526-j9kg00qf 288 12 47 47 CD cord-022526-j9kg00qf 288 13 and and CC cord-022526-j9kg00qf 288 14 epiploic epiploic JJ cord-022526-j9kg00qf 288 15 foramen foramen NN cord-022526-j9kg00qf 288 16 entrapments entrapment NNS cord-022526-j9kg00qf 288 17 as as IN cord-022526-j9kg00qf 288 18 edematous edematous JJ cord-022526-j9kg00qf 288 19 loops loop NNS cord-022526-j9kg00qf 288 20 of of IN cord-022526-j9kg00qf 288 21 small small JJ cord-022526-j9kg00qf 288 22 intestine intestine NN cord-022526-j9kg00qf 288 23 found find VBN cord-022526-j9kg00qf 288 24 in in IN cord-022526-j9kg00qf 288 25 the the DT cord-022526-j9kg00qf 288 26 right right JJ cord-022526-j9kg00qf 288 27 cranial cranial JJ cord-022526-j9kg00qf 288 28 abdomen abdomen NN cord-022526-j9kg00qf 288 29 . . . cord-022526-j9kg00qf 289 1 50 50 CD cord-022526-j9kg00qf 290 1 One one CD cord-022526-j9kg00qf 290 2 may may MD cord-022526-j9kg00qf 290 3 note note VB cord-022526-j9kg00qf 290 4 small small JJ cord-022526-j9kg00qf 290 5 intestinal intestinal JJ cord-022526-j9kg00qf 290 6 intussusceptions intussusception NNS cord-022526-j9kg00qf 290 7 as as IN cord-022526-j9kg00qf 290 8 targetlike targetlike NN cord-022526-j9kg00qf 290 9 lesions lesion NNS cord-022526-j9kg00qf 290 10 when when WRB cord-022526-j9kg00qf 290 11 viewed view VBN cord-022526-j9kg00qf 290 12 in in IN cord-022526-j9kg00qf 290 13 cross cross NN cord-022526-j9kg00qf 290 14 sections section NNS cord-022526-j9kg00qf 290 15 . . . cord-022526-j9kg00qf 291 1 51 51 CD cord-022526-j9kg00qf 292 1 The the DT cord-022526-j9kg00qf 292 2 presence presence NN cord-022526-j9kg00qf 292 3 of of IN cord-022526-j9kg00qf 292 4 bowel bowel NN cord-022526-j9kg00qf 292 5 loops loop NNS cord-022526-j9kg00qf 292 6 , , , cord-022526-j9kg00qf 292 7 stomach stomach NN cord-022526-j9kg00qf 292 8 , , , cord-022526-j9kg00qf 292 9 or or CC cord-022526-j9kg00qf 292 10 liver liver NN cord-022526-j9kg00qf 292 11 in in IN cord-022526-j9kg00qf 292 12 the the DT cord-022526-j9kg00qf 292 13 thoracic thoracic JJ cord-022526-j9kg00qf 292 14 cavity cavity NN cord-022526-j9kg00qf 292 15 indicates indicate VBZ cord-022526-j9kg00qf 292 16 the the DT cord-022526-j9kg00qf 292 17 presence presence NN cord-022526-j9kg00qf 292 18 of of IN cord-022526-j9kg00qf 292 19 herniation herniation NN cord-022526-j9kg00qf 292 20 through through IN cord-022526-j9kg00qf 292 21 the the DT cord-022526-j9kg00qf 292 22 diaphragm diaphragm NN cord-022526-j9kg00qf 292 23 and and CC cord-022526-j9kg00qf 292 24 should should MD cord-022526-j9kg00qf 292 25 be be VB cord-022526-j9kg00qf 292 26 confirmed confirm VBN cord-022526-j9kg00qf 292 27 using use VBG cord-022526-j9kg00qf 292 28 radiography radiography NN cord-022526-j9kg00qf 292 29 or or CC cord-022526-j9kg00qf 292 30 surgical surgical JJ cord-022526-j9kg00qf 292 31 exploration exploration NN cord-022526-j9kg00qf 292 32 . . . cord-022526-j9kg00qf 293 1 Evaluation evaluation NN cord-022526-j9kg00qf 293 2 of of IN cord-022526-j9kg00qf 293 3 the the DT cord-022526-j9kg00qf 293 4 large large JJ cord-022526-j9kg00qf 293 5 intestine intestine NN cord-022526-j9kg00qf 293 6 may may MD cord-022526-j9kg00qf 293 7 be be VB cord-022526-j9kg00qf 293 8 difficult difficult JJ cord-022526-j9kg00qf 293 9 because because IN cord-022526-j9kg00qf 293 10 of of IN cord-022526-j9kg00qf 293 11 the the DT cord-022526-j9kg00qf 293 12 large large JJ cord-022526-j9kg00qf 293 13 amounts amount NNS cord-022526-j9kg00qf 293 14 of of IN cord-022526-j9kg00qf 293 15 gas gas NN cord-022526-j9kg00qf 293 16 within within IN cord-022526-j9kg00qf 293 17 the the DT cord-022526-j9kg00qf 293 18 lumen lumen NN cord-022526-j9kg00qf 293 19 . . . cord-022526-j9kg00qf 294 1 However however RB cord-022526-j9kg00qf 294 2 , , , cord-022526-j9kg00qf 294 3 certain certain JJ cord-022526-j9kg00qf 294 4 disorders disorder NNS cord-022526-j9kg00qf 294 5 are be VBP cord-022526-j9kg00qf 294 6 readily readily RB cord-022526-j9kg00qf 294 7 identifiable identifiable JJ cord-022526-j9kg00qf 294 8 via via IN cord-022526-j9kg00qf 294 9 ultrasonography ultrasonography NN cord-022526-j9kg00qf 294 10 . . . cord-022526-j9kg00qf 295 1 One one PRP cord-022526-j9kg00qf 295 2 can can MD cord-022526-j9kg00qf 295 3 assess assess VB cord-022526-j9kg00qf 295 4 the the DT cord-022526-j9kg00qf 295 5 nephrosplenic nephrosplenic NNP cord-022526-j9kg00qf 295 6 ligament ligament NN cord-022526-j9kg00qf 295 7 area area NN cord-022526-j9kg00qf 295 8 for for IN cord-022526-j9kg00qf 295 9 bowel bowel NN cord-022526-j9kg00qf 295 10 entrapment entrapment NN cord-022526-j9kg00qf 295 11 in in IN cord-022526-j9kg00qf 295 12 the the DT cord-022526-j9kg00qf 295 13 left left JJ cord-022526-j9kg00qf 295 14 paralumbar paralumbar NN cord-022526-j9kg00qf 295 15 fossa fossa NN cord-022526-j9kg00qf 295 16 . . . cord-022526-j9kg00qf 296 1 In in IN cord-022526-j9kg00qf 296 2 cases case NNS cord-022526-j9kg00qf 296 3 of of IN cord-022526-j9kg00qf 296 4 entrapment entrapment NN cord-022526-j9kg00qf 296 5 , , , cord-022526-j9kg00qf 296 6 the the DT cord-022526-j9kg00qf 296 7 spleen spleen NN cord-022526-j9kg00qf 296 8 will will MD cord-022526-j9kg00qf 296 9 be be VB cord-022526-j9kg00qf 296 10 pulled pull VBN cord-022526-j9kg00qf 296 11 away away RB cord-022526-j9kg00qf 296 12 from from IN cord-022526-j9kg00qf 296 13 the the DT cord-022526-j9kg00qf 296 14 body body NN cord-022526-j9kg00qf 296 15 wall wall NN cord-022526-j9kg00qf 296 16 and and CC cord-022526-j9kg00qf 296 17 fluid fluid NN cord-022526-j9kg00qf 296 18 or or CC cord-022526-j9kg00qf 296 19 gas gas NN cord-022526-j9kg00qf 296 20 shadows shadow NNS cord-022526-j9kg00qf 296 21 will will MD cord-022526-j9kg00qf 296 22 be be VB cord-022526-j9kg00qf 296 23 observable observable JJ cord-022526-j9kg00qf 296 24 dorsal dorsal NN cord-022526-j9kg00qf 296 25 to to IN cord-022526-j9kg00qf 296 26 the the DT cord-022526-j9kg00qf 296 27 spleen spleen NN cord-022526-j9kg00qf 296 28 , , , cord-022526-j9kg00qf 296 29 52 52 CD cord-022526-j9kg00qf 296 30 obscuring obscure VBG cord-022526-j9kg00qf 296 31 the the DT cord-022526-j9kg00qf 296 32 kidney kidney NN cord-022526-j9kg00qf 296 33 , , , cord-022526-j9kg00qf 296 34 which which WDT cord-022526-j9kg00qf 296 35 is be VBZ cord-022526-j9kg00qf 296 36 normally normally RB cord-022526-j9kg00qf 296 37 adjacent adjacent JJ cord-022526-j9kg00qf 296 38 and and CC cord-022526-j9kg00qf 296 39 abaxial abaxial NN cord-022526-j9kg00qf 296 40 to to IN cord-022526-j9kg00qf 296 41 the the DT cord-022526-j9kg00qf 296 42 spleen spleen NN cord-022526-j9kg00qf 296 43 . . . cord-022526-j9kg00qf 297 1 Small small JJ cord-022526-j9kg00qf 297 2 colon colon NN cord-022526-j9kg00qf 297 3 , , , cord-022526-j9kg00qf 297 4 small small JJ cord-022526-j9kg00qf 297 5 intestine intestine NN cord-022526-j9kg00qf 297 6 , , , cord-022526-j9kg00qf 297 7 or or CC cord-022526-j9kg00qf 297 8 pneumoperitoneum pneumoperitoneum NNP cord-022526-j9kg00qf 297 9 also also RB cord-022526-j9kg00qf 297 10 may may MD cord-022526-j9kg00qf 297 11 produce produce VB cord-022526-j9kg00qf 297 12 a a DT cord-022526-j9kg00qf 297 13 gas gas NN cord-022526-j9kg00qf 297 14 shadow shadow NN cord-022526-j9kg00qf 297 15 and and CC cord-022526-j9kg00qf 297 16 obscure obscure VB cord-022526-j9kg00qf 297 17 the the DT cord-022526-j9kg00qf 297 18 kidney kidney NN cord-022526-j9kg00qf 297 19 from from IN cord-022526-j9kg00qf 297 20 view view NN cord-022526-j9kg00qf 297 21 . . . cord-022526-j9kg00qf 298 1 47 47 CD cord-022526-j9kg00qf 298 2 Sand sand NN cord-022526-j9kg00qf 298 3 impactions impaction NNS cord-022526-j9kg00qf 298 4 may may MD cord-022526-j9kg00qf 298 5 appear appear VB cord-022526-j9kg00qf 298 6 as as IN cord-022526-j9kg00qf 298 7 hyperechoic hyperechoic NNP cord-022526-j9kg00qf 298 8 bands band NNS cord-022526-j9kg00qf 298 9 on on IN cord-022526-j9kg00qf 298 10 the the DT cord-022526-j9kg00qf 298 11 ventral ventral JJ cord-022526-j9kg00qf 298 12 abdominal abdominal JJ cord-022526-j9kg00qf 298 13 wall wall NN cord-022526-j9kg00qf 298 14 . . . cord-022526-j9kg00qf 299 1 47 47 CD cord-022526-j9kg00qf 300 1 One one CD cord-022526-j9kg00qf 300 2 may may MD cord-022526-j9kg00qf 300 3 see see VB cord-022526-j9kg00qf 300 4 ileocecal ileocecal JJ cord-022526-j9kg00qf 300 5 and and CC cord-022526-j9kg00qf 300 6 cecocolic cecocolic NNP cord-022526-j9kg00qf 300 7 intussusceptions intussusception NNS cord-022526-j9kg00qf 300 8 in in IN cord-022526-j9kg00qf 300 9 the the DT cord-022526-j9kg00qf 300 10 upper upper JJ cord-022526-j9kg00qf 300 11 right right JJ cord-022526-j9kg00qf 300 12 paralumbar paralumbar NN cord-022526-j9kg00qf 300 13 fossa fossa NN cord-022526-j9kg00qf 300 14 . . . cord-022526-j9kg00qf 301 1 53 53 CD cord-022526-j9kg00qf 302 1 In in IN cord-022526-j9kg00qf 302 2 cases case NNS cord-022526-j9kg00qf 302 3 of of IN cord-022526-j9kg00qf 302 4 colitis colitis NN cord-022526-j9kg00qf 302 5 , , , cord-022526-j9kg00qf 302 6 large large JJ cord-022526-j9kg00qf 302 7 , , , cord-022526-j9kg00qf 302 8 fluid fluid NN cord-022526-j9kg00qf 302 9 - - HYPH cord-022526-j9kg00qf 302 10 filled fill VBN cord-022526-j9kg00qf 302 11 colons colon NNS cord-022526-j9kg00qf 302 12 may may MD cord-022526-j9kg00qf 302 13 be be VB cord-022526-j9kg00qf 302 14 visible visible JJ cord-022526-j9kg00qf 302 15 with with IN cord-022526-j9kg00qf 302 16 or or CC cord-022526-j9kg00qf 302 17 without without IN cord-022526-j9kg00qf 302 18 intramural intramural JJ cord-022526-j9kg00qf 302 19 edema edema NN cord-022526-j9kg00qf 302 20 . . . cord-022526-j9kg00qf 303 1 One one PRP cord-022526-j9kg00qf 303 2 can can MD cord-022526-j9kg00qf 303 3 find find VB cord-022526-j9kg00qf 303 4 the the DT cord-022526-j9kg00qf 303 5 right right JJ cord-022526-j9kg00qf 303 6 dorsal dorsal JJ cord-022526-j9kg00qf 303 7 colon colon NN cord-022526-j9kg00qf 303 8 consistently consistently RB cord-022526-j9kg00qf 303 9 abaxial abaxial VBZ cord-022526-j9kg00qf 303 10 to to IN cord-022526-j9kg00qf 303 11 the the DT cord-022526-j9kg00qf 303 12 liver liver NN cord-022526-j9kg00qf 303 13 , , , cord-022526-j9kg00qf 303 14 within within IN cord-022526-j9kg00qf 303 15 the the DT cord-022526-j9kg00qf 303 16 right right JJ cord-022526-j9kg00qf 303 17 thirteenth thirteenth NN cord-022526-j9kg00qf 303 18 to to IN cord-022526-j9kg00qf 303 19 fifteenth fifteenth JJ cord-022526-j9kg00qf 303 20 intercostal intercostal JJ cord-022526-j9kg00qf 303 21 space space NN cord-022526-j9kg00qf 303 22 and and CC cord-022526-j9kg00qf 303 23 may may MD cord-022526-j9kg00qf 303 24 be be VB cord-022526-j9kg00qf 303 25 thickened thicken VBN cord-022526-j9kg00qf 303 26 ( ( -LRB- cord-022526-j9kg00qf 303 27 > > NFP cord-022526-j9kg00qf 303 28 5 5 CD cord-022526-j9kg00qf 303 29 mm mm NNP cord-022526-j9kg00qf 303 30 ) ) -RRB- cord-022526-j9kg00qf 303 31 in in IN cord-022526-j9kg00qf 303 32 cases case NNS cord-022526-j9kg00qf 303 33 of of IN cord-022526-j9kg00qf 303 34 right right JJ cord-022526-j9kg00qf 303 35 dorsal dorsal JJ cord-022526-j9kg00qf 303 36 colitis colitis NN cord-022526-j9kg00qf 303 37 . . . cord-022526-j9kg00qf 304 1 Evaluation evaluation NN cord-022526-j9kg00qf 304 2 of of IN cord-022526-j9kg00qf 304 3 the the DT cord-022526-j9kg00qf 304 4 abdomen abdomen NN cord-022526-j9kg00qf 304 5 always always RB cord-022526-j9kg00qf 304 6 should should MD cord-022526-j9kg00qf 304 7 include include VB cord-022526-j9kg00qf 304 8 assessment assessment NN cord-022526-j9kg00qf 304 9 of of IN cord-022526-j9kg00qf 304 10 the the DT cord-022526-j9kg00qf 304 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 304 12 space space NN cord-022526-j9kg00qf 304 13 for for IN cord-022526-j9kg00qf 304 14 any any DT cord-022526-j9kg00qf 304 15 evidence evidence NN cord-022526-j9kg00qf 304 16 of of IN cord-022526-j9kg00qf 304 17 an an DT cord-022526-j9kg00qf 304 18 increased increase VBN cord-022526-j9kg00qf 304 19 amount amount NN cord-022526-j9kg00qf 304 20 of of IN cord-022526-j9kg00qf 304 21 PF pf NN cord-022526-j9kg00qf 304 22 or or CC cord-022526-j9kg00qf 304 23 increased increase VBN cord-022526-j9kg00qf 304 24 cellularity cellularity NN cord-022526-j9kg00qf 304 25 of of IN cord-022526-j9kg00qf 304 26 the the DT cord-022526-j9kg00qf 304 27 fluid fluid NN cord-022526-j9kg00qf 304 28 as as IN cord-022526-j9kg00qf 304 29 indicated indicate VBN cord-022526-j9kg00qf 304 30 by by IN cord-022526-j9kg00qf 304 31 an an DT cord-022526-j9kg00qf 304 32 increase increase NN cord-022526-j9kg00qf 304 33 in in IN cord-022526-j9kg00qf 304 34 echogenicity echogenicity NN cord-022526-j9kg00qf 304 35 . . . cord-022526-j9kg00qf 305 1 Ultrasonography Ultrasonography NNP cord-022526-j9kg00qf 305 2 also also RB cord-022526-j9kg00qf 305 3 can can MD cord-022526-j9kg00qf 305 4 be be VB cord-022526-j9kg00qf 305 5 useful useful JJ cord-022526-j9kg00qf 305 6 in in IN cord-022526-j9kg00qf 305 7 determining determine VBG cord-022526-j9kg00qf 305 8 the the DT cord-022526-j9kg00qf 305 9 ideal ideal JJ cord-022526-j9kg00qf 305 10 location location NN cord-022526-j9kg00qf 305 11 for for IN cord-022526-j9kg00qf 305 12 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 305 13 . . . cord-022526-j9kg00qf 306 1 One one CD cord-022526-j9kg00qf 306 2 also also RB cord-022526-j9kg00qf 306 3 should should MD cord-022526-j9kg00qf 306 4 evaluate evaluate VB cord-022526-j9kg00qf 306 5 the the DT cord-022526-j9kg00qf 306 6 liver liver NN cord-022526-j9kg00qf 306 7 , , , cord-022526-j9kg00qf 306 8 kidneys kidney NNS cord-022526-j9kg00qf 306 9 , , , cord-022526-j9kg00qf 306 10 and and CC cord-022526-j9kg00qf 306 11 spleen spleen NNS cord-022526-j9kg00qf 306 12 . . . cord-022526-j9kg00qf 307 1 One one CD cord-022526-j9kg00qf 307 2 may may MD cord-022526-j9kg00qf 307 3 detect detect VB cord-022526-j9kg00qf 307 4 choleliths choleliths NNP cord-022526-j9kg00qf 307 5 , , , cord-022526-j9kg00qf 307 6 nephroliths nephrolith NNS cord-022526-j9kg00qf 307 7 , , , cord-022526-j9kg00qf 307 8 masses masse NNS cord-022526-j9kg00qf 307 9 , , , cord-022526-j9kg00qf 307 10 abscesses abscess NNS cord-022526-j9kg00qf 307 11 , , , cord-022526-j9kg00qf 307 12 or or CC cord-022526-j9kg00qf 307 13 enlargement enlargement NN cord-022526-j9kg00qf 307 14 of of IN cord-022526-j9kg00qf 307 15 any any DT cord-022526-j9kg00qf 307 16 of of IN cord-022526-j9kg00qf 307 17 these these DT cord-022526-j9kg00qf 307 18 organs organ NNS cord-022526-j9kg00qf 307 19 . . . cord-022526-j9kg00qf 308 1 Abscesses abscess NNS cord-022526-j9kg00qf 308 2 or or CC cord-022526-j9kg00qf 308 3 tumors tumor NNS cord-022526-j9kg00qf 308 4 not not RB cord-022526-j9kg00qf 308 5 associated associate VBN cord-022526-j9kg00qf 308 6 with with IN cord-022526-j9kg00qf 308 7 visceral visceral JJ cord-022526-j9kg00qf 308 8 organs organ NNS cord-022526-j9kg00qf 308 9 may may MD cord-022526-j9kg00qf 308 10 be be VB cord-022526-j9kg00qf 308 11 difficult difficult JJ cord-022526-j9kg00qf 308 12 to to TO cord-022526-j9kg00qf 308 13 visualize visualize VB cord-022526-j9kg00qf 308 14 and and CC cord-022526-j9kg00qf 308 15 interpret interpret VB cord-022526-j9kg00qf 308 16 via via IN cord-022526-j9kg00qf 308 17 ultrasonography ultrasonography NN cord-022526-j9kg00qf 308 18 . . . cord-022526-j9kg00qf 309 1 Although although IN cord-022526-j9kg00qf 309 2 more more RBR cord-022526-j9kg00qf 309 3 commonly commonly RB cord-022526-j9kg00qf 309 4 used use VBN cord-022526-j9kg00qf 309 5 to to TO cord-022526-j9kg00qf 309 6 diagnose diagnose VB cord-022526-j9kg00qf 309 7 lameness lameness NN cord-022526-j9kg00qf 309 8 and and CC cord-022526-j9kg00qf 309 9 musculoskeletal musculoskeletal JJ cord-022526-j9kg00qf 309 10 problems problem NNS cord-022526-j9kg00qf 309 11 , , , cord-022526-j9kg00qf 309 12 nuclear nuclear JJ cord-022526-j9kg00qf 309 13 scintigraphy scintigraphy NN cord-022526-j9kg00qf 309 14 has have VBZ cord-022526-j9kg00qf 309 15 several several JJ cord-022526-j9kg00qf 309 16 uses use NNS cord-022526-j9kg00qf 309 17 for for IN cord-022526-j9kg00qf 309 18 evaluation evaluation NN cord-022526-j9kg00qf 309 19 of of IN cord-022526-j9kg00qf 309 20 the the DT cord-022526-j9kg00qf 309 21 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 309 22 tract tract NN cord-022526-j9kg00qf 309 23 . . . cord-022526-j9kg00qf 310 1 Scintigraphy Scintigraphy NNP cord-022526-j9kg00qf 310 2 is be VBZ cord-022526-j9kg00qf 310 3 now now RB cord-022526-j9kg00qf 310 4 available available JJ cord-022526-j9kg00qf 310 5 at at IN cord-022526-j9kg00qf 310 6 most most JJS cord-022526-j9kg00qf 310 7 universities university NNS cord-022526-j9kg00qf 310 8 and and CC cord-022526-j9kg00qf 310 9 many many JJ cord-022526-j9kg00qf 310 10 private private JJ cord-022526-j9kg00qf 310 11 referral referral NN cord-022526-j9kg00qf 310 12 hospitals hospital NNS cord-022526-j9kg00qf 310 13 . . . cord-022526-j9kg00qf 311 1 One one PRP cord-022526-j9kg00qf 311 2 must must MD cord-022526-j9kg00qf 311 3 use use VB cord-022526-j9kg00qf 311 4 proper proper JJ cord-022526-j9kg00qf 311 5 isolation isolation NN cord-022526-j9kg00qf 311 6 protocols protocol NNS cord-022526-j9kg00qf 311 7 and and CC cord-022526-j9kg00qf 311 8 waste waste NN cord-022526-j9kg00qf 311 9 disposal disposal NN cord-022526-j9kg00qf 311 10 techniques technique NNS cord-022526-j9kg00qf 311 11 strictly strictly RB cord-022526-j9kg00qf 311 12 . . . cord-022526-j9kg00qf 312 1 The the DT cord-022526-j9kg00qf 312 2 procedure procedure NN cord-022526-j9kg00qf 312 3 requires require VBZ cord-022526-j9kg00qf 312 4 special special JJ cord-022526-j9kg00qf 312 5 gamma gamma NN cord-022526-j9kg00qf 312 6 cameras camera NNS cord-022526-j9kg00qf 312 7 and and CC cord-022526-j9kg00qf 312 8 the the DT cord-022526-j9kg00qf 312 9 injection injection NN cord-022526-j9kg00qf 312 10 of of IN cord-022526-j9kg00qf 312 11 radioactive radioactive JJ cord-022526-j9kg00qf 312 12 materials material NNS cord-022526-j9kg00qf 312 13 into into IN cord-022526-j9kg00qf 312 14 the the DT cord-022526-j9kg00qf 312 15 bloodstream bloodstream NN cord-022526-j9kg00qf 312 16 . . . cord-022526-j9kg00qf 313 1 One one PRP cord-022526-j9kg00qf 313 2 can can MD cord-022526-j9kg00qf 313 3 use use VB cord-022526-j9kg00qf 313 4 one one CD cord-022526-j9kg00qf 313 5 of of IN cord-022526-j9kg00qf 313 6 two two CD cord-022526-j9kg00qf 313 7 methods method NNS cord-022526-j9kg00qf 313 8 : : : cord-022526-j9kg00qf 313 9 injection injection NN cord-022526-j9kg00qf 313 10 of of IN cord-022526-j9kg00qf 313 11 technetium-99 technetium-99 CD cord-022526-j9kg00qf 313 12 m m NN cord-022526-j9kg00qf 313 13 methylene methylene NN cord-022526-j9kg00qf 313 14 diphosphonate diphosphonate NN cord-022526-j9kg00qf 313 15 ( ( -LRB- cord-022526-j9kg00qf 313 16 99 99 CD cord-022526-j9kg00qf 313 17 m m NNP cord-022526-j9kg00qf 313 18 Tc Tc NNP cord-022526-j9kg00qf 313 19 - - HYPH cord-022526-j9kg00qf 313 20 MDP MDP NNP cord-022526-j9kg00qf 313 21 ) ) -RRB- cord-022526-j9kg00qf 313 22 directly directly RB cord-022526-j9kg00qf 313 23 into into IN cord-022526-j9kg00qf 313 24 the the DT cord-022526-j9kg00qf 313 25 blood blood NN cord-022526-j9kg00qf 313 26 or or CC cord-022526-j9kg00qf 313 27 injection injection NN cord-022526-j9kg00qf 313 28 of of IN cord-022526-j9kg00qf 313 29 99 99 CD cord-022526-j9kg00qf 313 30 m m NN cord-022526-j9kg00qf 313 31 Tc Tc NNP cord-022526-j9kg00qf 313 32 - - HYPH cord-022526-j9kg00qf 313 33 labeled label VBN cord-022526-j9kg00qf 313 34 leukocytes leukocyte NNS cord-022526-j9kg00qf 313 35 . . . cord-022526-j9kg00qf 314 1 Labeling labeling NN cord-022526-j9kg00qf 314 2 of of IN cord-022526-j9kg00qf 314 3 leukocytes leukocyte NNS cord-022526-j9kg00qf 314 4 involves involve VBZ cord-022526-j9kg00qf 314 5 aseptically aseptically RB cord-022526-j9kg00qf 314 6 collecting collect VBG cord-022526-j9kg00qf 314 7 heparinized heparinize VBN cord-022526-j9kg00qf 314 8 blood blood NN cord-022526-j9kg00qf 314 9 samples sample NNS cord-022526-j9kg00qf 314 10 , , , cord-022526-j9kg00qf 314 11 isolating isolate VBG cord-022526-j9kg00qf 314 12 the the DT cord-022526-j9kg00qf 314 13 buffy buffy NNP cord-022526-j9kg00qf 314 14 coat coat NN cord-022526-j9kg00qf 314 15 , , , cord-022526-j9kg00qf 314 16 and and CC cord-022526-j9kg00qf 314 17 mixing mix VBG cord-022526-j9kg00qf 314 18 those those DT cord-022526-j9kg00qf 314 19 leukocytes leukocyte NNS cord-022526-j9kg00qf 314 20 with with IN cord-022526-j9kg00qf 314 21 a a DT cord-022526-j9kg00qf 314 22 radioactive radioactive JJ cord-022526-j9kg00qf 314 23 dye dye NN cord-022526-j9kg00qf 314 24 ( ( -LRB- cord-022526-j9kg00qf 314 25 99 99 CD cord-022526-j9kg00qf 314 26 m m NN cord-022526-j9kg00qf 314 27 Tc Tc NNP cord-022526-j9kg00qf 314 28 hexamethylpropyleneamine hexamethylpropyleneamine NN cord-022526-j9kg00qf 314 29 oxime oxime NN cord-022526-j9kg00qf 314 30 , , , cord-022526-j9kg00qf 314 31 or or CC cord-022526-j9kg00qf 314 32 99 99 CD cord-022526-j9kg00qf 314 33 m m NN cord-022526-j9kg00qf 314 34 Tc Tc NNP cord-022526-j9kg00qf 314 35 - - HYPH cord-022526-j9kg00qf 314 36 HMPAO HMPAO NNP cord-022526-j9kg00qf 314 37 ) ) -RRB- cord-022526-j9kg00qf 314 38 in in IN cord-022526-j9kg00qf 314 39 vitro vitro FW cord-022526-j9kg00qf 314 40 . . . cord-022526-j9kg00qf 315 1 54 54 CD cord-022526-j9kg00qf 316 1 One one CD cord-022526-j9kg00qf 316 2 then then RB cord-022526-j9kg00qf 316 3 reinjects reinject VBZ cord-022526-j9kg00qf 316 4 the the DT cord-022526-j9kg00qf 316 5 labeled labeled JJ cord-022526-j9kg00qf 316 6 leukocytes leukocyte NNS cord-022526-j9kg00qf 316 7 and and CC cord-022526-j9kg00qf 316 8 obtains obtain VBZ cord-022526-j9kg00qf 316 9 images image NNS cord-022526-j9kg00qf 316 10 . . . cord-022526-j9kg00qf 317 1 The the DT cord-022526-j9kg00qf 317 2 principle principle NN cord-022526-j9kg00qf 317 3 of of IN cord-022526-j9kg00qf 317 4 nuclear nuclear JJ cord-022526-j9kg00qf 317 5 scintigraphy scintigraphy NN cord-022526-j9kg00qf 317 6 then then RB cord-022526-j9kg00qf 317 7 lies lie VBZ cord-022526-j9kg00qf 317 8 in in IN cord-022526-j9kg00qf 317 9 increased increase VBN cord-022526-j9kg00qf 317 10 uptake uptake NN cord-022526-j9kg00qf 317 11 of of IN cord-022526-j9kg00qf 317 12 the the DT cord-022526-j9kg00qf 317 13 dye dye NN cord-022526-j9kg00qf 317 14 or or CC cord-022526-j9kg00qf 317 15 the the DT cord-022526-j9kg00qf 317 16 white white JJ cord-022526-j9kg00qf 317 17 blood blood NN cord-022526-j9kg00qf 317 18 cells cell NNS cord-022526-j9kg00qf 317 19 into into IN cord-022526-j9kg00qf 317 20 areas area NNS cord-022526-j9kg00qf 317 21 of of IN cord-022526-j9kg00qf 317 22 inflammation inflammation NN cord-022526-j9kg00qf 317 23 . . . cord-022526-j9kg00qf 318 1 One one CD cord-022526-j9kg00qf 318 2 of of IN cord-022526-j9kg00qf 318 3 the the DT cord-022526-j9kg00qf 318 4 most most RBS cord-022526-j9kg00qf 318 5 common common JJ cord-022526-j9kg00qf 318 6 uses use NNS cord-022526-j9kg00qf 318 7 of of IN cord-022526-j9kg00qf 318 8 nuclear nuclear JJ cord-022526-j9kg00qf 318 9 scintigraphy scintigraphy NN cord-022526-j9kg00qf 318 10 in in IN cord-022526-j9kg00qf 318 11 evaluating evaluate VBG cord-022526-j9kg00qf 318 12 the the DT cord-022526-j9kg00qf 318 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 318 14 tract tract NN cord-022526-j9kg00qf 318 15 is be VBZ cord-022526-j9kg00qf 318 16 diagnosis diagnosis NN cord-022526-j9kg00qf 318 17 of of IN cord-022526-j9kg00qf 318 18 dental dental JJ cord-022526-j9kg00qf 318 19 disease disease NN cord-022526-j9kg00qf 318 20 . . . cord-022526-j9kg00qf 319 1 Scintigraphy Scintigraphy NNP cord-022526-j9kg00qf 319 2 using use VBG cord-022526-j9kg00qf 319 3 99 99 CD cord-022526-j9kg00qf 319 4 m m NNP cord-022526-j9kg00qf 319 5 Tc Tc NNP cord-022526-j9kg00qf 319 6 - - HYPH cord-022526-j9kg00qf 319 7 MDP MDP NNP cord-022526-j9kg00qf 319 8 proved prove VBD cord-022526-j9kg00qf 319 9 to to TO cord-022526-j9kg00qf 319 10 be be VB cord-022526-j9kg00qf 319 11 more more RBR cord-022526-j9kg00qf 319 12 sensitive sensitive JJ cord-022526-j9kg00qf 319 13 in in IN cord-022526-j9kg00qf 319 14 cases case NNS cord-022526-j9kg00qf 319 15 of of IN cord-022526-j9kg00qf 319 16 dental dental JJ cord-022526-j9kg00qf 319 17 disease disease NN cord-022526-j9kg00qf 319 18 than than IN cord-022526-j9kg00qf 319 19 was be VBD cord-022526-j9kg00qf 319 20 radiography radiography NN cord-022526-j9kg00qf 319 21 . . . cord-022526-j9kg00qf 320 1 Scintigraphy Scintigraphy NNP cord-022526-j9kg00qf 320 2 was be VBD cord-022526-j9kg00qf 320 3 slightly slightly RB cord-022526-j9kg00qf 320 4 less less RBR cord-022526-j9kg00qf 320 5 specific specific JJ cord-022526-j9kg00qf 320 6 , , , cord-022526-j9kg00qf 320 7 however however RB cord-022526-j9kg00qf 320 8 , , , cord-022526-j9kg00qf 320 9 and and CC cord-022526-j9kg00qf 320 10 therefore therefore RB cord-022526-j9kg00qf 320 11 should should MD cord-022526-j9kg00qf 320 12 be be VB cord-022526-j9kg00qf 320 13 used use VBN cord-022526-j9kg00qf 320 14 with with IN cord-022526-j9kg00qf 320 15 radiography radiography NN cord-022526-j9kg00qf 320 16 or or CC cord-022526-j9kg00qf 320 17 computed compute VBN cord-022526-j9kg00qf 320 18 tomography tomography NN cord-022526-j9kg00qf 320 19 for for IN cord-022526-j9kg00qf 320 20 ultimate ultimate JJ cord-022526-j9kg00qf 320 21 accuracy accuracy NN cord-022526-j9kg00qf 320 22 . . . cord-022526-j9kg00qf 321 1 55 55 CD cord-022526-j9kg00qf 321 2 Scintigraphy Scintigraphy NNP cord-022526-j9kg00qf 321 3 using use VBG cord-022526-j9kg00qf 321 4 radiolabeled radiolabele VBN cord-022526-j9kg00qf 321 5 white white JJ cord-022526-j9kg00qf 321 6 blood blood NN cord-022526-j9kg00qf 321 7 cells cell NNS cord-022526-j9kg00qf 321 8 can can MD cord-022526-j9kg00qf 321 9 support support VB cord-022526-j9kg00qf 321 10 a a DT cord-022526-j9kg00qf 321 11 diagnosis diagnosis NN cord-022526-j9kg00qf 321 12 of of IN cord-022526-j9kg00qf 321 13 right right JJ cord-022526-j9kg00qf 321 14 dorsal dorsal JJ cord-022526-j9kg00qf 321 15 colitis colitis NN cord-022526-j9kg00qf 321 16 in in IN cord-022526-j9kg00qf 321 17 the the DT cord-022526-j9kg00qf 321 18 horse horse NN cord-022526-j9kg00qf 321 19 . . . cord-022526-j9kg00qf 322 1 40 40 CD cord-022526-j9kg00qf 322 2 Images image NNS cord-022526-j9kg00qf 322 3 taken take VBN cord-022526-j9kg00qf 322 4 of of IN cord-022526-j9kg00qf 322 5 the the DT cord-022526-j9kg00qf 322 6 abdomen abdomen JJ cord-022526-j9kg00qf 322 7 20 20 CD cord-022526-j9kg00qf 322 8 hours hour NNS cord-022526-j9kg00qf 322 9 after after IN cord-022526-j9kg00qf 322 10 injection injection NN cord-022526-j9kg00qf 322 11 showed show VBD cord-022526-j9kg00qf 322 12 an an DT cord-022526-j9kg00qf 322 13 increased increase VBN cord-022526-j9kg00qf 322 14 linear linear JJ cord-022526-j9kg00qf 322 15 uptake uptake NN cord-022526-j9kg00qf 322 16 of of IN cord-022526-j9kg00qf 322 17 leukocytes leukocyte NNS cord-022526-j9kg00qf 322 18 in in IN cord-022526-j9kg00qf 322 19 the the DT cord-022526-j9kg00qf 322 20 region region NN cord-022526-j9kg00qf 322 21 of of IN cord-022526-j9kg00qf 322 22 the the DT cord-022526-j9kg00qf 322 23 right right JJ cord-022526-j9kg00qf 322 24 dorsal dorsal JJ cord-022526-j9kg00qf 322 25 colon colon NN cord-022526-j9kg00qf 322 26 in in IN cord-022526-j9kg00qf 322 27 horses horse NNS cord-022526-j9kg00qf 322 28 with with IN cord-022526-j9kg00qf 322 29 right right JJ cord-022526-j9kg00qf 322 30 dorsal dorsal JJ cord-022526-j9kg00qf 322 31 colitis colitis NN cord-022526-j9kg00qf 322 32 compared compare VBN cord-022526-j9kg00qf 322 33 with with IN cord-022526-j9kg00qf 322 34 normal normal JJ cord-022526-j9kg00qf 322 35 horses horse NNS cord-022526-j9kg00qf 322 36 . . . cord-022526-j9kg00qf 323 1 This this DT cord-022526-j9kg00qf 323 2 technique technique NN cord-022526-j9kg00qf 323 3 also also RB cord-022526-j9kg00qf 323 4 may may MD cord-022526-j9kg00qf 323 5 prove prove VB cord-022526-j9kg00qf 323 6 useful useful JJ cord-022526-j9kg00qf 323 7 for for IN cord-022526-j9kg00qf 323 8 diagnosing diagnose VBG cord-022526-j9kg00qf 323 9 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 323 10 abscesses abscess NNS cord-022526-j9kg00qf 323 11 in in IN cord-022526-j9kg00qf 323 12 the the DT cord-022526-j9kg00qf 323 13 horse horse NN cord-022526-j9kg00qf 323 14 . . . cord-022526-j9kg00qf 324 1 Other other JJ cord-022526-j9kg00qf 324 2 uses use NNS cord-022526-j9kg00qf 324 3 of of IN cord-022526-j9kg00qf 324 4 nuclear nuclear JJ cord-022526-j9kg00qf 324 5 scintigraphy scintigraphy NN cord-022526-j9kg00qf 324 6 include include VBP cord-022526-j9kg00qf 324 7 evaluation evaluation NN cord-022526-j9kg00qf 324 8 of of IN cord-022526-j9kg00qf 324 9 metastasis metastasis NN cord-022526-j9kg00qf 324 10 of of IN cord-022526-j9kg00qf 324 11 abdominal abdominal JJ cord-022526-j9kg00qf 324 12 tumors tumor NNS cord-022526-j9kg00qf 324 13 to to IN cord-022526-j9kg00qf 324 14 bony bony JJ cord-022526-j9kg00qf 324 15 areas area NNS cord-022526-j9kg00qf 324 16 , , , cord-022526-j9kg00qf 324 17 assessment assessment NN cord-022526-j9kg00qf 324 18 of of IN cord-022526-j9kg00qf 324 19 biliary biliary JJ cord-022526-j9kg00qf 324 20 kinetics kinetic NNS cord-022526-j9kg00qf 324 21 , , , cord-022526-j9kg00qf 324 22 and and CC cord-022526-j9kg00qf 324 23 determination determination NN cord-022526-j9kg00qf 324 24 of of IN cord-022526-j9kg00qf 324 25 gastric gastric JJ cord-022526-j9kg00qf 324 26 emptying emptying NN cord-022526-j9kg00qf 324 27 times time NNS cord-022526-j9kg00qf 324 28 . . . cord-022526-j9kg00qf 325 1 [ [ -LRB- cord-022526-j9kg00qf 325 2 56 56 CD cord-022526-j9kg00qf 325 3 ] ] -RRB- cord-022526-j9kg00qf 325 4 [ [ -LRB- cord-022526-j9kg00qf 325 5 57 57 CD cord-022526-j9kg00qf 325 6 ] ] -RRB- cord-022526-j9kg00qf 325 7 [ [ -LRB- cord-022526-j9kg00qf 325 8 58 58 CD cord-022526-j9kg00qf 325 9 ] ] -RRB- cord-022526-j9kg00qf 326 1 Endoscopy Endoscopy NNP cord-022526-j9kg00qf 326 2 Endoscopic endoscopic JJ cord-022526-j9kg00qf 326 3 examination examination NN cord-022526-j9kg00qf 326 4 of of IN cord-022526-j9kg00qf 326 5 the the DT cord-022526-j9kg00qf 326 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 326 7 tract tract NN cord-022526-j9kg00qf 326 8 begins begin VBZ cord-022526-j9kg00qf 326 9 with with IN cord-022526-j9kg00qf 326 10 evaluation evaluation NN cord-022526-j9kg00qf 326 11 of of IN cord-022526-j9kg00qf 326 12 the the DT cord-022526-j9kg00qf 326 13 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 326 14 area area NN cord-022526-j9kg00qf 326 15 by by IN cord-022526-j9kg00qf 326 16 examination examination NN cord-022526-j9kg00qf 326 17 for for IN cord-022526-j9kg00qf 326 18 any any DT cord-022526-j9kg00qf 326 19 signs sign NNS cord-022526-j9kg00qf 326 20 of of IN cord-022526-j9kg00qf 326 21 collapse collapse NN cord-022526-j9kg00qf 326 22 or or CC cord-022526-j9kg00qf 326 23 dysfunction dysfunction NN cord-022526-j9kg00qf 326 24 . . . cord-022526-j9kg00qf 327 1 One one PRP cord-022526-j9kg00qf 327 2 should should MD cord-022526-j9kg00qf 327 3 evaluate evaluate VB cord-022526-j9kg00qf 327 4 the the DT cord-022526-j9kg00qf 327 5 ability ability NN cord-022526-j9kg00qf 327 6 of of IN cord-022526-j9kg00qf 327 7 the the DT cord-022526-j9kg00qf 327 8 horse horse NN cord-022526-j9kg00qf 327 9 to to TO cord-022526-j9kg00qf 327 10 swallow swallow VB cord-022526-j9kg00qf 327 11 . . . cord-022526-j9kg00qf 328 1 The the DT cord-022526-j9kg00qf 328 2 floor floor NN cord-022526-j9kg00qf 328 3 of of IN cord-022526-j9kg00qf 328 4 the the DT cord-022526-j9kg00qf 328 5 pharynx pharynx NN cord-022526-j9kg00qf 328 6 should should MD cord-022526-j9kg00qf 328 7 be be VB cord-022526-j9kg00qf 328 8 clean clean JJ cord-022526-j9kg00qf 328 9 and and CC cord-022526-j9kg00qf 328 10 free free JJ cord-022526-j9kg00qf 328 11 of of IN cord-022526-j9kg00qf 328 12 feed feed NN cord-022526-j9kg00qf 328 13 material material NN cord-022526-j9kg00qf 328 14 and and CC cord-022526-j9kg00qf 328 15 foreign foreign JJ cord-022526-j9kg00qf 328 16 bodies body NNS cord-022526-j9kg00qf 328 17 . . . cord-022526-j9kg00qf 329 1 One one PRP cord-022526-j9kg00qf 329 2 can can MD cord-022526-j9kg00qf 329 3 examine examine VB cord-022526-j9kg00qf 329 4 the the DT cord-022526-j9kg00qf 329 5 oral oral JJ cord-022526-j9kg00qf 329 6 cavity cavity NN cord-022526-j9kg00qf 329 7 with with IN cord-022526-j9kg00qf 329 8 the the DT cord-022526-j9kg00qf 329 9 horse horse NN cord-022526-j9kg00qf 329 10 under under IN cord-022526-j9kg00qf 329 11 heavy heavy JJ cord-022526-j9kg00qf 329 12 sedation sedation NN cord-022526-j9kg00qf 329 13 or or CC cord-022526-j9kg00qf 329 14 anesthesia anesthesia NN cord-022526-j9kg00qf 329 15 and and CC cord-022526-j9kg00qf 329 16 with with IN cord-022526-j9kg00qf 329 17 the the DT cord-022526-j9kg00qf 329 18 help help NN cord-022526-j9kg00qf 329 19 of of IN cord-022526-j9kg00qf 329 20 a a DT cord-022526-j9kg00qf 329 21 full full JJ cord-022526-j9kg00qf 329 22 - - HYPH cord-022526-j9kg00qf 329 23 mouth mouth NN cord-022526-j9kg00qf 329 24 speculum speculum NN cord-022526-j9kg00qf 329 25 . . . cord-022526-j9kg00qf 330 1 One one PRP cord-022526-j9kg00qf 330 2 can can MD cord-022526-j9kg00qf 330 3 examine examine VB cord-022526-j9kg00qf 330 4 the the DT cord-022526-j9kg00qf 330 5 teeth tooth NNS cord-022526-j9kg00qf 330 6 for for IN cord-022526-j9kg00qf 330 7 any any DT cord-022526-j9kg00qf 330 8 irregularities irregularity NNS cord-022526-j9kg00qf 330 9 , , , cord-022526-j9kg00qf 330 10 obvious obvious JJ cord-022526-j9kg00qf 330 11 cavities cavity NNS cord-022526-j9kg00qf 330 12 , , , cord-022526-j9kg00qf 330 13 sharp sharp JJ cord-022526-j9kg00qf 330 14 points point NNS cord-022526-j9kg00qf 330 15 , , , cord-022526-j9kg00qf 330 16 or or CC cord-022526-j9kg00qf 330 17 hooks hook NNS cord-022526-j9kg00qf 330 18 and and CC cord-022526-j9kg00qf 330 19 the the DT cord-022526-j9kg00qf 330 20 hard hard JJ cord-022526-j9kg00qf 330 21 and and CC cord-022526-j9kg00qf 330 22 soft soft JJ cord-022526-j9kg00qf 330 23 palpate palpate NN cord-022526-j9kg00qf 330 24 for for IN cord-022526-j9kg00qf 330 25 completeness completeness NN cord-022526-j9kg00qf 330 26 and and CC cord-022526-j9kg00qf 330 27 any any DT cord-022526-j9kg00qf 330 28 evidence evidence NN cord-022526-j9kg00qf 330 29 of of IN cord-022526-j9kg00qf 330 30 ulceration ulceration NN cord-022526-j9kg00qf 330 31 , , , cord-022526-j9kg00qf 330 32 masses masse NNS cord-022526-j9kg00qf 330 33 , , , cord-022526-j9kg00qf 330 34 or or CC cord-022526-j9kg00qf 330 35 foreign foreign JJ cord-022526-j9kg00qf 330 36 bodies body NNS cord-022526-j9kg00qf 330 37 . . . cord-022526-j9kg00qf 331 1 One one PRP cord-022526-j9kg00qf 331 2 should should MD cord-022526-j9kg00qf 331 3 use use VB cord-022526-j9kg00qf 331 4 a a DT cord-022526-j9kg00qf 331 5 3-m 3-m CD cord-022526-j9kg00qf 331 6 flexible flexible JJ cord-022526-j9kg00qf 331 7 fiberoptic fiberoptic JJ cord-022526-j9kg00qf 331 8 endoscope endoscope NN cord-022526-j9kg00qf 331 9 to to TO cord-022526-j9kg00qf 331 10 examine examine VB cord-022526-j9kg00qf 331 11 the the DT cord-022526-j9kg00qf 331 12 esophagus esophagus NN cord-022526-j9kg00qf 331 13 , , , cord-022526-j9kg00qf 331 14 which which WDT cord-022526-j9kg00qf 331 15 is be VBZ cord-022526-j9kg00qf 331 16 accomplished accomplish VBN cord-022526-j9kg00qf 331 17 best well RBS cord-022526-j9kg00qf 331 18 by by IN cord-022526-j9kg00qf 331 19 passing pass VBG cord-022526-j9kg00qf 331 20 the the DT cord-022526-j9kg00qf 331 21 endoscope endoscope NN cord-022526-j9kg00qf 331 22 into into IN cord-022526-j9kg00qf 331 23 the the DT cord-022526-j9kg00qf 331 24 stomach stomach NN cord-022526-j9kg00qf 331 25 and and CC cord-022526-j9kg00qf 331 26 viewing view VBG cord-022526-j9kg00qf 331 27 the the DT cord-022526-j9kg00qf 331 28 esophagus esophagus NN cord-022526-j9kg00qf 331 29 as as IN cord-022526-j9kg00qf 331 30 one one CD cord-022526-j9kg00qf 331 31 withdraws withdraw VBZ cord-022526-j9kg00qf 331 32 the the DT cord-022526-j9kg00qf 331 33 endoscope endoscope NN cord-022526-j9kg00qf 331 34 while while IN cord-022526-j9kg00qf 331 35 dilating dilate VBG cord-022526-j9kg00qf 331 36 the the DT cord-022526-j9kg00qf 331 37 lumen lumen NN cord-022526-j9kg00qf 331 38 with with IN cord-022526-j9kg00qf 331 39 air air NN cord-022526-j9kg00qf 331 40 . . . cord-022526-j9kg00qf 332 1 The the DT cord-022526-j9kg00qf 332 2 esophageal esophageal JJ cord-022526-j9kg00qf 332 3 mucosa mucosa NN cord-022526-j9kg00qf 332 4 normally normally RB cord-022526-j9kg00qf 332 5 should should MD cord-022526-j9kg00qf 332 6 be be VB cord-022526-j9kg00qf 332 7 a a DT cord-022526-j9kg00qf 332 8 glistening glisten VBG cord-022526-j9kg00qf 332 9 , , , cord-022526-j9kg00qf 332 10 light light JJ cord-022526-j9kg00qf 332 11 pink pink JJ cord-022526-j9kg00qf 332 12 color color NN cord-022526-j9kg00qf 332 13 . . . cord-022526-j9kg00qf 333 1 Ulceration ulceration NN cord-022526-j9kg00qf 333 2 can can MD cord-022526-j9kg00qf 333 3 occur occur VB cord-022526-j9kg00qf 333 4 with with IN cord-022526-j9kg00qf 333 5 cases case NNS cord-022526-j9kg00qf 333 6 of of IN cord-022526-j9kg00qf 333 7 choke choke NN cord-022526-j9kg00qf 333 8 , , , cord-022526-j9kg00qf 333 9 reflux reflux NN cord-022526-j9kg00qf 333 10 esophagitis esophagitis NN cord-022526-j9kg00qf 333 11 or or CC cord-022526-j9kg00qf 333 12 in in IN cord-022526-j9kg00qf 333 13 horses horse NNS cord-022526-j9kg00qf 333 14 that that WDT cord-022526-j9kg00qf 333 15 have have VBP cord-022526-j9kg00qf 333 16 had have VBN cord-022526-j9kg00qf 333 17 an an DT cord-022526-j9kg00qf 333 18 indwelling indwell VBG cord-022526-j9kg00qf 333 19 nasogastric nasogastric NN cord-022526-j9kg00qf 333 20 tube tube NN cord-022526-j9kg00qf 333 21 . . . cord-022526-j9kg00qf 334 1 Erosions erosion NNS cord-022526-j9kg00qf 334 2 may may MD cord-022526-j9kg00qf 334 3 be be VB cord-022526-j9kg00qf 334 4 punctate punctate NNP cord-022526-j9kg00qf 334 5 , , , cord-022526-j9kg00qf 334 6 linear linear NNP cord-022526-j9kg00qf 334 7 , , , cord-022526-j9kg00qf 334 8 or or CC cord-022526-j9kg00qf 334 9 circumferential circumferential NN cord-022526-j9kg00qf 334 10 . . . cord-022526-j9kg00qf 335 1 One one PRP cord-022526-j9kg00qf 335 2 should should MD cord-022526-j9kg00qf 335 3 evaluate evaluate VB cord-022526-j9kg00qf 335 4 carefully carefully RB cord-022526-j9kg00qf 335 5 for for IN cord-022526-j9kg00qf 335 6 any any DT cord-022526-j9kg00qf 335 7 ulcers ulcer NNS cord-022526-j9kg00qf 335 8 to to TO cord-022526-j9kg00qf 335 9 ensure ensure VB cord-022526-j9kg00qf 335 10 that that IN cord-022526-j9kg00qf 335 11 no no DT cord-022526-j9kg00qf 335 12 areas area NNS cord-022526-j9kg00qf 335 13 of of IN cord-022526-j9kg00qf 335 14 perforation perforation NN cord-022526-j9kg00qf 335 15 through through IN cord-022526-j9kg00qf 335 16 the the DT cord-022526-j9kg00qf 335 17 entire entire JJ cord-022526-j9kg00qf 335 18 thickness thickness NN cord-022526-j9kg00qf 335 19 of of IN cord-022526-j9kg00qf 335 20 the the DT cord-022526-j9kg00qf 335 21 esophageal esophageal JJ cord-022526-j9kg00qf 335 22 wall wall NN cord-022526-j9kg00qf 335 23 exist exist VBP cord-022526-j9kg00qf 335 24 . . . cord-022526-j9kg00qf 336 1 Distinguishing distinguish VBG cord-022526-j9kg00qf 336 2 normal normal JJ cord-022526-j9kg00qf 336 3 peristaltic peristaltic JJ cord-022526-j9kg00qf 336 4 contractions contraction NNS cord-022526-j9kg00qf 336 5 from from IN cord-022526-j9kg00qf 336 6 areas area NNS cord-022526-j9kg00qf 336 7 of of IN cord-022526-j9kg00qf 336 8 stricture stricture NN cord-022526-j9kg00qf 336 9 requires require VBZ cord-022526-j9kg00qf 336 10 observation observation NN cord-022526-j9kg00qf 336 11 of of IN cord-022526-j9kg00qf 336 12 the the DT cord-022526-j9kg00qf 336 13 area area NN cord-022526-j9kg00qf 336 14 and and CC cord-022526-j9kg00qf 336 15 its -PRON- PRP$ cord-022526-j9kg00qf 336 16 motility motility NN cord-022526-j9kg00qf 336 17 over over IN cord-022526-j9kg00qf 336 18 time time NN cord-022526-j9kg00qf 336 19 . . . cord-022526-j9kg00qf 337 1 One one CD cord-022526-j9kg00qf 337 2 also also RB cord-022526-j9kg00qf 337 3 may may MD cord-022526-j9kg00qf 337 4 note note VB cord-022526-j9kg00qf 337 5 diverticula diverticula NN cord-022526-j9kg00qf 337 6 as as IN cord-022526-j9kg00qf 337 7 outpouchings outpouching NNS cord-022526-j9kg00qf 337 8 of of IN cord-022526-j9kg00qf 337 9 the the DT cord-022526-j9kg00qf 337 10 mucosa mucosa NN cord-022526-j9kg00qf 337 11 , , , cord-022526-j9kg00qf 337 12 sometimes sometimes RB cord-022526-j9kg00qf 337 13 associated associate VBN cord-022526-j9kg00qf 337 14 with with IN cord-022526-j9kg00qf 337 15 a a DT cord-022526-j9kg00qf 337 16 stricture stricture NN cord-022526-j9kg00qf 337 17 distally distally RB cord-022526-j9kg00qf 337 18 . . . cord-022526-j9kg00qf 338 1 Megaesophagus Megaesophagus NNP cord-022526-j9kg00qf 338 2 , , , cord-022526-j9kg00qf 338 3 although although IN cord-022526-j9kg00qf 338 4 rare rare JJ cord-022526-j9kg00qf 338 5 , , , cord-022526-j9kg00qf 338 6 appears appear VBZ cord-022526-j9kg00qf 338 7 as as IN cord-022526-j9kg00qf 338 8 a a DT cord-022526-j9kg00qf 338 9 generalized generalized JJ cord-022526-j9kg00qf 338 10 dilation dilation NN cord-022526-j9kg00qf 338 11 of of IN cord-022526-j9kg00qf 338 12 the the DT cord-022526-j9kg00qf 338 13 esophagus esophagus NN cord-022526-j9kg00qf 338 14 . . . cord-022526-j9kg00qf 339 1 One one CD cord-022526-j9kg00qf 339 2 may may MD cord-022526-j9kg00qf 339 3 detect detect VB cord-022526-j9kg00qf 339 4 food food NN cord-022526-j9kg00qf 339 5 or or CC cord-022526-j9kg00qf 339 6 foreign foreign JJ cord-022526-j9kg00qf 339 7 body body NN cord-022526-j9kg00qf 339 8 impactions impaction NNS cord-022526-j9kg00qf 339 9 of of IN cord-022526-j9kg00qf 339 10 the the DT cord-022526-j9kg00qf 339 11 esophagus esophagus NN cord-022526-j9kg00qf 339 12 via via IN cord-022526-j9kg00qf 339 13 endoscopy endoscopy NN cord-022526-j9kg00qf 339 14 . . . cord-022526-j9kg00qf 340 1 One one CD cord-022526-j9kg00qf 340 2 always always RB cord-022526-j9kg00qf 340 3 should should MD cord-022526-j9kg00qf 340 4 reevaluate reevaluate VB cord-022526-j9kg00qf 340 5 the the DT cord-022526-j9kg00qf 340 6 esophagus esophagus NN cord-022526-j9kg00qf 340 7 after after IN cord-022526-j9kg00qf 340 8 removing remove VBG cord-022526-j9kg00qf 340 9 any any DT cord-022526-j9kg00qf 340 10 obstruction obstruction NN cord-022526-j9kg00qf 340 11 to to TO cord-022526-j9kg00qf 340 12 detect detect VB cord-022526-j9kg00qf 340 13 the the DT cord-022526-j9kg00qf 340 14 presence presence NN cord-022526-j9kg00qf 340 15 of of IN cord-022526-j9kg00qf 340 16 complications complication NNS cord-022526-j9kg00qf 340 17 ( ( -LRB- cord-022526-j9kg00qf 340 18 ulceration ulceration NN cord-022526-j9kg00qf 340 19 , , , cord-022526-j9kg00qf 340 20 rupture rupture NN cord-022526-j9kg00qf 340 21 ) ) -RRB- cord-022526-j9kg00qf 340 22 or or CC cord-022526-j9kg00qf 340 23 initiating initiate VBG cord-022526-j9kg00qf 340 24 causes cause NNS cord-022526-j9kg00qf 340 25 ( ( -LRB- cord-022526-j9kg00qf 340 26 strictures stricture NNS cord-022526-j9kg00qf 340 27 , , , cord-022526-j9kg00qf 340 28 diverticula diverticula NN cord-022526-j9kg00qf 340 29 , , , cord-022526-j9kg00qf 340 30 and and CC cord-022526-j9kg00qf 340 31 masses masse NNS cord-022526-j9kg00qf 340 32 ) ) -RRB- cord-022526-j9kg00qf 340 33 . . . cord-022526-j9kg00qf 341 1 A a DT cord-022526-j9kg00qf 341 2 3-m 3-m CD cord-022526-j9kg00qf 341 3 flexible flexible JJ cord-022526-j9kg00qf 341 4 endoscope endoscope NN cord-022526-j9kg00qf 341 5 also also RB cord-022526-j9kg00qf 341 6 allows allow VBZ cord-022526-j9kg00qf 341 7 examination examination NN cord-022526-j9kg00qf 341 8 of of IN cord-022526-j9kg00qf 341 9 the the DT cord-022526-j9kg00qf 341 10 stomach stomach NN cord-022526-j9kg00qf 341 11 . . . cord-022526-j9kg00qf 342 1 The the DT cord-022526-j9kg00qf 342 2 horse horse NN cord-022526-j9kg00qf 342 3 should should MD cord-022526-j9kg00qf 342 4 be be VB cord-022526-j9kg00qf 342 5 fasted fast VBN cord-022526-j9kg00qf 342 6 for for IN cord-022526-j9kg00qf 342 7 at at RB cord-022526-j9kg00qf 342 8 least least RBS cord-022526-j9kg00qf 342 9 12 12 CD cord-022526-j9kg00qf 342 10 hours hour NNS cord-022526-j9kg00qf 342 11 before before IN cord-022526-j9kg00qf 342 12 endoscopy endoscopy NN cord-022526-j9kg00qf 342 13 . . . cord-022526-j9kg00qf 343 1 One one PRP cord-022526-j9kg00qf 343 2 can can MD cord-022526-j9kg00qf 343 3 examine examine VB cord-022526-j9kg00qf 343 4 the the DT cord-022526-j9kg00qf 343 5 cardia cardia NN cord-022526-j9kg00qf 343 6 and and CC cord-022526-j9kg00qf 343 7 fundus fundus NN cord-022526-j9kg00qf 343 8 easily easily RB cord-022526-j9kg00qf 343 9 , , , cord-022526-j9kg00qf 343 10 as as RB cord-022526-j9kg00qf 343 11 well well RB cord-022526-j9kg00qf 343 12 as as IN cord-022526-j9kg00qf 343 13 the the DT cord-022526-j9kg00qf 343 14 margo margo NNP cord-022526-j9kg00qf 343 15 plicatus plicatus NNP cord-022526-j9kg00qf 343 16 . . . cord-022526-j9kg00qf 344 1 The the DT cord-022526-j9kg00qf 344 2 squamous squamous JJ cord-022526-j9kg00qf 344 3 mucosa mucosa NN cord-022526-j9kg00qf 344 4 should should MD cord-022526-j9kg00qf 344 5 resemble resemble VB cord-022526-j9kg00qf 344 6 the the DT cord-022526-j9kg00qf 344 7 esophageal esophageal JJ cord-022526-j9kg00qf 344 8 mucosa mucosa NN cord-022526-j9kg00qf 344 9 . . . cord-022526-j9kg00qf 345 1 The the DT cord-022526-j9kg00qf 345 2 glandular glandular JJ cord-022526-j9kg00qf 345 3 mucosa mucosa NN cord-022526-j9kg00qf 345 4 should should MD cord-022526-j9kg00qf 345 5 be be VB cord-022526-j9kg00qf 345 6 glistening glisten VBG cord-022526-j9kg00qf 345 7 red red JJ cord-022526-j9kg00qf 345 8 and and CC cord-022526-j9kg00qf 345 9 may may MD cord-022526-j9kg00qf 345 10 have have VB cord-022526-j9kg00qf 345 11 a a DT cord-022526-j9kg00qf 345 12 reticulated reticulated JJ cord-022526-j9kg00qf 345 13 pattern pattern NN cord-022526-j9kg00qf 345 14 . . . cord-022526-j9kg00qf 346 1 One one PRP cord-022526-j9kg00qf 346 2 should should MD cord-022526-j9kg00qf 346 3 carefully carefully RB cord-022526-j9kg00qf 346 4 examine examine VB cord-022526-j9kg00qf 346 5 for for IN cord-022526-j9kg00qf 346 6 evidence evidence NN cord-022526-j9kg00qf 346 7 of of IN cord-022526-j9kg00qf 346 8 ulceration ulceration NN cord-022526-j9kg00qf 346 9 or or CC cord-022526-j9kg00qf 346 10 masses masse NNS cord-022526-j9kg00qf 346 11 . . . cord-022526-j9kg00qf 347 1 One one PRP cord-022526-j9kg00qf 347 2 can can MD cord-022526-j9kg00qf 347 3 obtain obtain VB cord-022526-j9kg00qf 347 4 transendoscopic transendoscopic NNP cord-022526-j9kg00qf 347 5 biopsy biopsy NNP cord-022526-j9kg00qf 347 6 material material NN cord-022526-j9kg00qf 347 7 easily easily RB cord-022526-j9kg00qf 347 8 from from IN cord-022526-j9kg00qf 347 9 esophageal esophageal JJ cord-022526-j9kg00qf 347 10 , , , cord-022526-j9kg00qf 347 11 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 347 12 , , , cord-022526-j9kg00qf 347 13 or or CC cord-022526-j9kg00qf 347 14 gastric gastric JJ cord-022526-j9kg00qf 347 15 masses masse NNS cord-022526-j9kg00qf 347 16 , , , cord-022526-j9kg00qf 347 17 and and CC cord-022526-j9kg00qf 347 18 because because IN cord-022526-j9kg00qf 347 19 the the DT cord-022526-j9kg00qf 347 20 biopsy biopsy NN cord-022526-j9kg00qf 347 21 size size NN cord-022526-j9kg00qf 347 22 will will MD cord-022526-j9kg00qf 347 23 be be VB cord-022526-j9kg00qf 347 24 small small JJ cord-022526-j9kg00qf 347 25 , , , cord-022526-j9kg00qf 347 26 one one PRP cord-022526-j9kg00qf 347 27 should should MD cord-022526-j9kg00qf 347 28 take take VB cord-022526-j9kg00qf 347 29 several several JJ cord-022526-j9kg00qf 347 30 samples sample NNS cord-022526-j9kg00qf 347 31 for for IN cord-022526-j9kg00qf 347 32 histopathologic histopathologic JJ cord-022526-j9kg00qf 347 33 examination examination NN cord-022526-j9kg00qf 347 34 . . . cord-022526-j9kg00qf 348 1 Pharmacologic Pharmacologic NNP cord-022526-j9kg00qf 348 2 agents agent NNS cord-022526-j9kg00qf 348 3 ( ( -LRB- cord-022526-j9kg00qf 348 4 bethanechol bethanechol NNP cord-022526-j9kg00qf 348 5 ) ) -RRB- cord-022526-j9kg00qf 348 6 to to TO cord-022526-j9kg00qf 348 7 empty empty VB cord-022526-j9kg00qf 348 8 the the DT cord-022526-j9kg00qf 348 9 stomach stomach NN cord-022526-j9kg00qf 348 10 and and CC cord-022526-j9kg00qf 348 11 provide provide VB cord-022526-j9kg00qf 348 12 complete complete JJ cord-022526-j9kg00qf 348 13 visualization visualization NN cord-022526-j9kg00qf 348 14 of of IN cord-022526-j9kg00qf 348 15 the the DT cord-022526-j9kg00qf 348 16 entire entire JJ cord-022526-j9kg00qf 348 17 fundic fundic NNP cord-022526-j9kg00qf 348 18 region region NN cord-022526-j9kg00qf 348 19 , , , cord-022526-j9kg00qf 348 20 the the DT cord-022526-j9kg00qf 348 21 pylorus pylorus NN cord-022526-j9kg00qf 348 22 , , , cord-022526-j9kg00qf 348 23 and and CC cord-022526-j9kg00qf 348 24 the the DT cord-022526-j9kg00qf 348 25 duodenum duodenum NN cord-022526-j9kg00qf 348 26 may may MD cord-022526-j9kg00qf 348 27 be be VB cord-022526-j9kg00qf 348 28 useful useful JJ cord-022526-j9kg00qf 348 29 . . . cord-022526-j9kg00qf 349 1 For for IN cord-022526-j9kg00qf 349 2 a a DT cord-022526-j9kg00qf 349 3 complete complete JJ cord-022526-j9kg00qf 349 4 description description NN cord-022526-j9kg00qf 349 5 of of IN cord-022526-j9kg00qf 349 6 gastroscopy gastroscopy NN cord-022526-j9kg00qf 349 7 and and CC cord-022526-j9kg00qf 349 8 evaluation evaluation NN cord-022526-j9kg00qf 349 9 of of IN cord-022526-j9kg00qf 349 10 gastric gastric JJ cord-022526-j9kg00qf 349 11 and and CC cord-022526-j9kg00qf 349 12 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 349 13 ulceration ulceration NN cord-022526-j9kg00qf 349 14 , , , cord-022526-j9kg00qf 349 15 please please UH cord-022526-j9kg00qf 349 16 refer refer VB cord-022526-j9kg00qf 349 17 to to IN cord-022526-j9kg00qf 349 18 Chapter chapter NN cord-022526-j9kg00qf 349 19 13.10 13.10 CD cord-022526-j9kg00qf 349 20 . . . cord-022526-j9kg00qf 350 1 D D NNP cord-022526-j9kg00qf 350 2 - - HYPH cord-022526-j9kg00qf 350 3 Glucose glucose NN cord-022526-j9kg00qf 350 4 or or CC cord-022526-j9kg00qf 350 5 D d NN cord-022526-j9kg00qf 350 6 - - HYPH cord-022526-j9kg00qf 350 7 xylose xylose NN cord-022526-j9kg00qf 350 8 absorption absorption NN cord-022526-j9kg00qf 350 9 tests test NNS cord-022526-j9kg00qf 350 10 are be VBP cord-022526-j9kg00qf 350 11 useful useful JJ cord-022526-j9kg00qf 350 12 in in IN cord-022526-j9kg00qf 350 13 determining determine VBG cord-022526-j9kg00qf 350 14 malabsorption malabsorption NN cord-022526-j9kg00qf 350 15 of of IN cord-022526-j9kg00qf 350 16 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 350 17 from from IN cord-022526-j9kg00qf 350 18 the the DT cord-022526-j9kg00qf 350 19 small small JJ cord-022526-j9kg00qf 350 20 intestine intestine NN cord-022526-j9kg00qf 350 21 in in IN cord-022526-j9kg00qf 350 22 horses horse NNS cord-022526-j9kg00qf 350 23 . . . cord-022526-j9kg00qf 351 1 The the DT cord-022526-j9kg00qf 351 2 protocol protocol NN cord-022526-j9kg00qf 351 3 for for IN cord-022526-j9kg00qf 351 4 absorption absorption NN cord-022526-j9kg00qf 351 5 tests test NNS cord-022526-j9kg00qf 351 6 using use VBG cord-022526-j9kg00qf 351 7 either either CC cord-022526-j9kg00qf 351 8 carbohydrate carbohydrate NN cord-022526-j9kg00qf 351 9 is be VBZ cord-022526-j9kg00qf 351 10 similar similar JJ cord-022526-j9kg00qf 351 11 . . . cord-022526-j9kg00qf 352 1 The the DT cord-022526-j9kg00qf 352 2 horse horse NN cord-022526-j9kg00qf 352 3 should should MD cord-022526-j9kg00qf 352 4 be be VB cord-022526-j9kg00qf 352 5 fasted fast VBN cord-022526-j9kg00qf 352 6 for for IN cord-022526-j9kg00qf 352 7 18 18 CD cord-022526-j9kg00qf 352 8 to to TO cord-022526-j9kg00qf 352 9 24 24 CD cord-022526-j9kg00qf 352 10 hours hour NNS cord-022526-j9kg00qf 352 11 before before IN cord-022526-j9kg00qf 352 12 testing testing NN cord-022526-j9kg00qf 352 13 . . . cord-022526-j9kg00qf 353 1 Increased increase VBN cord-022526-j9kg00qf 353 2 periods period NNS cord-022526-j9kg00qf 353 3 of of IN cord-022526-j9kg00qf 353 4 fasting fasting NN cord-022526-j9kg00qf 353 5 actually actually RB cord-022526-j9kg00qf 353 6 have have VBP cord-022526-j9kg00qf 353 7 been be VBN cord-022526-j9kg00qf 353 8 shown show VBN cord-022526-j9kg00qf 353 9 to to TO cord-022526-j9kg00qf 353 10 decrease decrease VB cord-022526-j9kg00qf 353 11 absorption absorption NN cord-022526-j9kg00qf 353 12 of of IN cord-022526-j9kg00qf 353 13 D d NN cord-022526-j9kg00qf 353 14 - - HYPH cord-022526-j9kg00qf 353 15 xylose xylose NN cord-022526-j9kg00qf 353 16 and and CC cord-022526-j9kg00qf 353 17 interfere interfere VB cord-022526-j9kg00qf 353 18 with with IN cord-022526-j9kg00qf 353 19 results result NNS cord-022526-j9kg00qf 353 20 . . . cord-022526-j9kg00qf 354 1 59 59 CD cord-022526-j9kg00qf 354 2 One one CD cord-022526-j9kg00qf 354 3 administers administer VBZ cord-022526-j9kg00qf 354 4 a a DT cord-022526-j9kg00qf 354 5 dosage dosage NN cord-022526-j9kg00qf 354 6 of of IN cord-022526-j9kg00qf 354 7 0.5 0.5 CD cord-022526-j9kg00qf 354 8 to to TO cord-022526-j9kg00qf 354 9 1 1 CD cord-022526-j9kg00qf 354 10 g g NN cord-022526-j9kg00qf 354 11 / / SYM cord-022526-j9kg00qf 354 12 kg kg NN cord-022526-j9kg00qf 354 13 of of IN cord-022526-j9kg00qf 354 14 D d NN cord-022526-j9kg00qf 354 15 - - HYPH cord-022526-j9kg00qf 354 16 glucose glucose NN cord-022526-j9kg00qf 354 17 or or CC cord-022526-j9kg00qf 354 18 D d NN cord-022526-j9kg00qf 354 19 - - HYPH cord-022526-j9kg00qf 354 20 xylose xylose NN cord-022526-j9kg00qf 354 21 via via IN cord-022526-j9kg00qf 354 22 a a DT cord-022526-j9kg00qf 354 23 nasogastric nasogastric NN cord-022526-j9kg00qf 354 24 tube tube NN cord-022526-j9kg00qf 354 25 . . . cord-022526-j9kg00qf 355 1 Administration administration NN cord-022526-j9kg00qf 355 2 of of IN cord-022526-j9kg00qf 355 3 sedatives sedative NNS cord-022526-j9kg00qf 355 4 may may MD cord-022526-j9kg00qf 355 5 increase increase VB cord-022526-j9kg00qf 355 6 the the DT cord-022526-j9kg00qf 355 7 blood blood NN cord-022526-j9kg00qf 355 8 glucose glucose NN cord-022526-j9kg00qf 355 9 levels level NNS cord-022526-j9kg00qf 355 10 falsely falsely RB cord-022526-j9kg00qf 355 11 and and CC cord-022526-j9kg00qf 355 12 interfere interfere VB cord-022526-j9kg00qf 355 13 with with IN cord-022526-j9kg00qf 355 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 355 15 transit transit NN cord-022526-j9kg00qf 355 16 times time NNS cord-022526-j9kg00qf 355 17 . . . cord-022526-j9kg00qf 356 1 One one CD cord-022526-j9kg00qf 356 2 then then RB cord-022526-j9kg00qf 356 3 collects collect VBZ cord-022526-j9kg00qf 356 4 blood blood NN cord-022526-j9kg00qf 356 5 samples sample NNS cord-022526-j9kg00qf 356 6 to to TO cord-022526-j9kg00qf 356 7 measure measure VB cord-022526-j9kg00qf 356 8 glucose glucose NN cord-022526-j9kg00qf 356 9 or or CC cord-022526-j9kg00qf 356 10 xylose xylose NN cord-022526-j9kg00qf 356 11 concentrations concentration NNS cord-022526-j9kg00qf 356 12 at at IN cord-022526-j9kg00qf 356 13 0 0 CD cord-022526-j9kg00qf 356 14 , , , cord-022526-j9kg00qf 356 15 30 30 CD cord-022526-j9kg00qf 356 16 , , , cord-022526-j9kg00qf 356 17 60 60 CD cord-022526-j9kg00qf 356 18 , , , cord-022526-j9kg00qf 356 19 90 90 CD cord-022526-j9kg00qf 356 20 , , , cord-022526-j9kg00qf 356 21 120 120 CD cord-022526-j9kg00qf 356 22 , , , cord-022526-j9kg00qf 356 23 150 150 CD cord-022526-j9kg00qf 356 24 , , , cord-022526-j9kg00qf 356 25 180 180 CD cord-022526-j9kg00qf 356 26 , , , cord-022526-j9kg00qf 356 27 210 210 CD cord-022526-j9kg00qf 356 28 , , , cord-022526-j9kg00qf 356 29 and and CC cord-022526-j9kg00qf 356 30 240 240 CD cord-022526-j9kg00qf 356 31 minutes minute NNS cord-022526-j9kg00qf 356 32 after after IN cord-022526-j9kg00qf 356 33 administration administration NN cord-022526-j9kg00qf 356 34 . . . cord-022526-j9kg00qf 357 1 One one CD cord-022526-j9kg00qf 357 2 may may MD cord-022526-j9kg00qf 357 3 take take VB cord-022526-j9kg00qf 357 4 additional additional JJ cord-022526-j9kg00qf 357 5 samples sample NNS cord-022526-j9kg00qf 357 6 up up IN cord-022526-j9kg00qf 357 7 to to TO cord-022526-j9kg00qf 357 8 6 6 CD cord-022526-j9kg00qf 357 9 hours hour NNS cord-022526-j9kg00qf 357 10 after after IN cord-022526-j9kg00qf 357 11 dosing dose VBG cord-022526-j9kg00qf 357 12 if if IN cord-022526-j9kg00qf 357 13 the the DT cord-022526-j9kg00qf 357 14 results result NNS cord-022526-j9kg00qf 357 15 are be VBP cord-022526-j9kg00qf 357 16 questionable questionable JJ cord-022526-j9kg00qf 357 17 . . . cord-022526-j9kg00qf 358 1 One one PRP cord-022526-j9kg00qf 358 2 should should MD cord-022526-j9kg00qf 358 3 measure measure VB cord-022526-j9kg00qf 358 4 glucose glucose NN cord-022526-j9kg00qf 358 5 in in IN cord-022526-j9kg00qf 358 6 blood blood NN cord-022526-j9kg00qf 358 7 samples sample NNS cord-022526-j9kg00qf 358 8 collected collect VBN cord-022526-j9kg00qf 358 9 with with IN cord-022526-j9kg00qf 358 10 sodium sodium NN cord-022526-j9kg00qf 358 11 fluoride fluoride NN cord-022526-j9kg00qf 358 12 as as IN cord-022526-j9kg00qf 358 13 an an DT cord-022526-j9kg00qf 358 14 anticoagulant anticoagulant NN cord-022526-j9kg00qf 358 15 and and CC cord-022526-j9kg00qf 358 16 measure measure NN cord-022526-j9kg00qf 358 17 xylose xylose NN cord-022526-j9kg00qf 358 18 in in IN cord-022526-j9kg00qf 358 19 samples sample NNS cord-022526-j9kg00qf 358 20 collected collect VBN cord-022526-j9kg00qf 358 21 in in IN cord-022526-j9kg00qf 358 22 heparinized heparinized JJ cord-022526-j9kg00qf 358 23 plasma plasma NN cord-022526-j9kg00qf 358 24 . . . cord-022526-j9kg00qf 359 1 A a DT cord-022526-j9kg00qf 359 2 normal normal JJ cord-022526-j9kg00qf 359 3 D d NN cord-022526-j9kg00qf 359 4 - - HYPH cord-022526-j9kg00qf 359 5 glucose glucose NN cord-022526-j9kg00qf 359 6 absorption absorption NN cord-022526-j9kg00qf 359 7 test test NN cord-022526-j9kg00qf 359 8 , , , cord-022526-j9kg00qf 359 9 also also RB cord-022526-j9kg00qf 359 10 known know VBN cord-022526-j9kg00qf 359 11 as as IN cord-022526-j9kg00qf 359 12 an an DT cord-022526-j9kg00qf 359 13 oral oral JJ cord-022526-j9kg00qf 359 14 glucose glucose NN cord-022526-j9kg00qf 359 15 tolerance tolerance NN cord-022526-j9kg00qf 359 16 test test NN cord-022526-j9kg00qf 359 17 , , , cord-022526-j9kg00qf 359 18 should should MD cord-022526-j9kg00qf 359 19 have have VB cord-022526-j9kg00qf 359 20 a a DT cord-022526-j9kg00qf 359 21 peak peak NN cord-022526-j9kg00qf 359 22 between between IN cord-022526-j9kg00qf 359 23 90 90 CD cord-022526-j9kg00qf 359 24 and and CC cord-022526-j9kg00qf 359 25 120 120 CD cord-022526-j9kg00qf 359 26 minutes minute NNS cord-022526-j9kg00qf 359 27 , , , cord-022526-j9kg00qf 359 28 and and CC cord-022526-j9kg00qf 359 29 this this DT cord-022526-j9kg00qf 359 30 peak peak NN cord-022526-j9kg00qf 359 31 should should MD cord-022526-j9kg00qf 359 32 be be VB cord-022526-j9kg00qf 359 33 greater great JJR cord-022526-j9kg00qf 359 34 than than IN cord-022526-j9kg00qf 359 35 85 85 CD cord-022526-j9kg00qf 359 36 % % NN cord-022526-j9kg00qf 359 37 above above IN cord-022526-j9kg00qf 359 38 the the DT cord-022526-j9kg00qf 359 39 resting rest VBG cord-022526-j9kg00qf 359 40 glucose glucose NN cord-022526-j9kg00qf 359 41 value value NN cord-022526-j9kg00qf 359 42 . . . cord-022526-j9kg00qf 360 1 60 60 CD cord-022526-j9kg00qf 360 2 Complete complete JJ cord-022526-j9kg00qf 360 3 malabsorption malabsorption NN cord-022526-j9kg00qf 360 4 is be VBZ cord-022526-j9kg00qf 360 5 defined define VBN cord-022526-j9kg00qf 360 6 as as IN cord-022526-j9kg00qf 360 7 a a DT cord-022526-j9kg00qf 360 8 peak peak NN cord-022526-j9kg00qf 360 9 less less JJR cord-022526-j9kg00qf 360 10 than than IN cord-022526-j9kg00qf 360 11 15 15 CD cord-022526-j9kg00qf 360 12 % % NN cord-022526-j9kg00qf 360 13 above above IN cord-022526-j9kg00qf 360 14 the the DT cord-022526-j9kg00qf 360 15 resting rest VBG cord-022526-j9kg00qf 360 16 levels level NNS cord-022526-j9kg00qf 360 17 , , , cord-022526-j9kg00qf 360 18 and and CC cord-022526-j9kg00qf 360 19 partial partial JJ cord-022526-j9kg00qf 360 20 malabsorption malabsorption NN cord-022526-j9kg00qf 360 21 is be VBZ cord-022526-j9kg00qf 360 22 defined define VBN cord-022526-j9kg00qf 360 23 as as IN cord-022526-j9kg00qf 360 24 a a DT cord-022526-j9kg00qf 360 25 peak peak NN cord-022526-j9kg00qf 360 26 between between IN cord-022526-j9kg00qf 360 27 15 15 CD cord-022526-j9kg00qf 360 28 % % NN cord-022526-j9kg00qf 360 29 and and CC cord-022526-j9kg00qf 360 30 85 85 CD cord-022526-j9kg00qf 360 31 % % NN cord-022526-j9kg00qf 360 32 above above IN cord-022526-j9kg00qf 360 33 the the DT cord-022526-j9kg00qf 360 34 resting rest VBG cord-022526-j9kg00qf 360 35 level level NN cord-022526-j9kg00qf 360 36 . . . cord-022526-j9kg00qf 361 1 One one PRP cord-022526-j9kg00qf 361 2 must must MD cord-022526-j9kg00qf 361 3 keep keep VB cord-022526-j9kg00qf 361 4 in in IN cord-022526-j9kg00qf 361 5 mind mind NN cord-022526-j9kg00qf 361 6 that that IN cord-022526-j9kg00qf 361 7 gastric gastric JJ cord-022526-j9kg00qf 361 8 emptying emptying NN cord-022526-j9kg00qf 361 9 , , , cord-022526-j9kg00qf 361 10 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 361 11 transit transit NN cord-022526-j9kg00qf 361 12 time time NN cord-022526-j9kg00qf 361 13 , , , cord-022526-j9kg00qf 361 14 length length NN cord-022526-j9kg00qf 361 15 of of IN cord-022526-j9kg00qf 361 16 fasting fast VBG cord-022526-j9kg00qf 361 17 , , , cord-022526-j9kg00qf 361 18 cellular cellular JJ cord-022526-j9kg00qf 361 19 uptake uptake NN cord-022526-j9kg00qf 361 20 and and CC cord-022526-j9kg00qf 361 21 metabolism metabolism NN cord-022526-j9kg00qf 361 22 , , , cord-022526-j9kg00qf 361 23 and and CC cord-022526-j9kg00qf 361 24 endocrine endocrine JJ cord-022526-j9kg00qf 361 25 function function NN cord-022526-j9kg00qf 361 26 influence influence VBP cord-022526-j9kg00qf 361 27 glucose glucose NN cord-022526-j9kg00qf 361 28 absorption absorption NN cord-022526-j9kg00qf 361 29 curves curve NNS cord-022526-j9kg00qf 361 30 . . . cord-022526-j9kg00qf 362 1 Malabsorption malabsorption NN cord-022526-j9kg00qf 362 2 demonstrated demonstrate VBN cord-022526-j9kg00qf 362 3 by by IN cord-022526-j9kg00qf 362 4 the the DT cord-022526-j9kg00qf 362 5 oral oral JJ cord-022526-j9kg00qf 362 6 glucose glucose NN cord-022526-j9kg00qf 362 7 tolerance tolerance NN cord-022526-j9kg00qf 362 8 test test NN cord-022526-j9kg00qf 362 9 is be VBZ cord-022526-j9kg00qf 362 10 sensitive sensitive JJ cord-022526-j9kg00qf 362 11 but but CC cord-022526-j9kg00qf 362 12 not not RB cord-022526-j9kg00qf 362 13 specific specific JJ cord-022526-j9kg00qf 362 14 . . . cord-022526-j9kg00qf 363 1 Diseases disease NNS cord-022526-j9kg00qf 363 2 that that WDT cord-022526-j9kg00qf 363 3 may may MD cord-022526-j9kg00qf 363 4 cause cause VB cord-022526-j9kg00qf 363 5 a a DT cord-022526-j9kg00qf 363 6 lowered lower VBN cord-022526-j9kg00qf 363 7 or or CC cord-022526-j9kg00qf 363 8 delayed delay VBN cord-022526-j9kg00qf 363 9 peak peak NN cord-022526-j9kg00qf 363 10 include include VBP cord-022526-j9kg00qf 363 11 infiltrative infiltrative JJ cord-022526-j9kg00qf 363 12 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 363 13 , , , cord-022526-j9kg00qf 363 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 363 15 bowel bowel NN cord-022526-j9kg00qf 363 16 disease disease NN cord-022526-j9kg00qf 363 17 ( ( -LRB- cord-022526-j9kg00qf 363 18 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 363 19 - - HYPH cord-022526-j9kg00qf 363 20 plasmacytic plasmacytic JJ cord-022526-j9kg00qf 363 21 or or CC cord-022526-j9kg00qf 363 22 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 363 23 ) ) -RRB- cord-022526-j9kg00qf 363 24 , , , cord-022526-j9kg00qf 363 25 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 363 26 , , , cord-022526-j9kg00qf 363 27 chronic chronic JJ cord-022526-j9kg00qf 363 28 colitis colitis NN cord-022526-j9kg00qf 363 29 ( ( -LRB- cord-022526-j9kg00qf 363 30 Salmonella Salmonella NNP cord-022526-j9kg00qf 363 31 sp sp NN cord-022526-j9kg00qf 363 32 . . . cord-022526-j9kg00qf 363 33 ) ) -RRB- cord-022526-j9kg00qf 363 34 , , , cord-022526-j9kg00qf 363 35 multisystemic multisystemic NNP cord-022526-j9kg00qf 363 36 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 363 37 epitheliotropic epitheliotropic NNP cord-022526-j9kg00qf 363 38 disease disease NN cord-022526-j9kg00qf 363 39 , , , cord-022526-j9kg00qf 363 40 food food NN cord-022526-j9kg00qf 363 41 allergies allergy NNS cord-022526-j9kg00qf 363 42 , , , cord-022526-j9kg00qf 363 43 and and CC cord-022526-j9kg00qf 363 44 small small JJ cord-022526-j9kg00qf 363 45 intestinal intestinal JJ cord-022526-j9kg00qf 363 46 bacterial bacterial JJ cord-022526-j9kg00qf 363 47 overgrowth overgrowth NN cord-022526-j9kg00qf 363 48 . . . cord-022526-j9kg00qf 364 1 61 61 CD cord-022526-j9kg00qf 364 2 D d NN cord-022526-j9kg00qf 364 3 - - HYPH cord-022526-j9kg00qf 364 4 Xylose Xylose NNP cord-022526-j9kg00qf 364 5 absorption absorption NN cord-022526-j9kg00qf 364 6 tests test NNS cord-022526-j9kg00qf 364 7 have have VBP cord-022526-j9kg00qf 364 8 some some DT cord-022526-j9kg00qf 364 9 advantages advantage NNS cord-022526-j9kg00qf 364 10 over over IN cord-022526-j9kg00qf 364 11 the the DT cord-022526-j9kg00qf 364 12 oral oral JJ cord-022526-j9kg00qf 364 13 glucose glucose NN cord-022526-j9kg00qf 364 14 tolerance tolerance NN cord-022526-j9kg00qf 364 15 test test NN cord-022526-j9kg00qf 364 16 because because IN cord-022526-j9kg00qf 364 17 xylose xylose NNP cord-022526-j9kg00qf 364 18 is be VBZ cord-022526-j9kg00qf 364 19 not not RB cord-022526-j9kg00qf 364 20 metabolized metabolize VBN cord-022526-j9kg00qf 364 21 in in IN cord-022526-j9kg00qf 364 22 the the DT cord-022526-j9kg00qf 364 23 small small JJ cord-022526-j9kg00qf 364 24 intestinal intestinal JJ cord-022526-j9kg00qf 364 25 mucosa mucosa NN cord-022526-j9kg00qf 364 26 and and CC cord-022526-j9kg00qf 364 27 insulin insulin NN cord-022526-j9kg00qf 364 28 does do VBZ cord-022526-j9kg00qf 364 29 not not RB cord-022526-j9kg00qf 364 30 influence influence VB cord-022526-j9kg00qf 364 31 its -PRON- PRP$ cord-022526-j9kg00qf 364 32 absorption absorption NN cord-022526-j9kg00qf 364 33 . . . cord-022526-j9kg00qf 365 1 Gastric gastric JJ cord-022526-j9kg00qf 365 2 and and CC cord-022526-j9kg00qf 365 3 intestinal intestinal JJ cord-022526-j9kg00qf 365 4 motility motility NN cord-022526-j9kg00qf 365 5 , , , cord-022526-j9kg00qf 365 6 intraluminal intraluminal JJ cord-022526-j9kg00qf 365 7 bacterial bacterial JJ cord-022526-j9kg00qf 365 8 overgrowth overgrowth NN cord-022526-j9kg00qf 365 9 , , , cord-022526-j9kg00qf 365 10 and and CC cord-022526-j9kg00qf 365 11 renal renal JJ cord-022526-j9kg00qf 365 12 function function NN cord-022526-j9kg00qf 365 13 still still RB cord-022526-j9kg00qf 365 14 influence influence VBP cord-022526-j9kg00qf 365 15 xylose xylose NN cord-022526-j9kg00qf 365 16 absorption absorption NN cord-022526-j9kg00qf 365 17 , , , cord-022526-j9kg00qf 365 18 because because IN cord-022526-j9kg00qf 365 19 the the DT cord-022526-j9kg00qf 365 20 kidneys kidney NNS cord-022526-j9kg00qf 365 21 clear clear JJ cord-022526-j9kg00qf 365 22 xylose xylose NN cord-022526-j9kg00qf 365 23 . . . cord-022526-j9kg00qf 366 1 61 61 CD cord-022526-j9kg00qf 367 1 The the DT cord-022526-j9kg00qf 367 2 other other JJ cord-022526-j9kg00qf 367 3 main main JJ cord-022526-j9kg00qf 367 4 drawback drawback NN cord-022526-j9kg00qf 367 5 to to IN cord-022526-j9kg00qf 367 6 D d NN cord-022526-j9kg00qf 367 7 - - HYPH cord-022526-j9kg00qf 367 8 xylose xylose NNP cord-022526-j9kg00qf 367 9 is be VBZ cord-022526-j9kg00qf 367 10 that that IN cord-022526-j9kg00qf 367 11 it -PRON- PRP cord-022526-j9kg00qf 367 12 is be VBZ cord-022526-j9kg00qf 367 13 generally generally RB cord-022526-j9kg00qf 367 14 available available JJ cord-022526-j9kg00qf 367 15 only only RB cord-022526-j9kg00qf 367 16 in in IN cord-022526-j9kg00qf 367 17 research research NN cord-022526-j9kg00qf 367 18 settings setting NNS cord-022526-j9kg00qf 367 19 . . . cord-022526-j9kg00qf 368 1 However however RB cord-022526-j9kg00qf 368 2 , , , cord-022526-j9kg00qf 368 3 xylose xylose NN cord-022526-j9kg00qf 368 4 measurements measurement NNS cord-022526-j9kg00qf 368 5 are be VBP cord-022526-j9kg00qf 368 6 available available JJ cord-022526-j9kg00qf 368 7 at at IN cord-022526-j9kg00qf 368 8 most most JJS cord-022526-j9kg00qf 368 9 major major JJ cord-022526-j9kg00qf 368 10 universities university NNS cord-022526-j9kg00qf 368 11 . . . cord-022526-j9kg00qf 369 1 A a DT cord-022526-j9kg00qf 369 2 normal normal JJ cord-022526-j9kg00qf 369 3 D d NN cord-022526-j9kg00qf 369 4 - - HYPH cord-022526-j9kg00qf 369 5 xylose xylose NN cord-022526-j9kg00qf 369 6 absorption absorption NN cord-022526-j9kg00qf 369 7 curve curve NN cord-022526-j9kg00qf 369 8 should should MD cord-022526-j9kg00qf 369 9 peak peak VB cord-022526-j9kg00qf 369 10 between between IN cord-022526-j9kg00qf 369 11 20 20 CD cord-022526-j9kg00qf 369 12 and and CC cord-022526-j9kg00qf 369 13 25 25 CD cord-022526-j9kg00qf 369 14 mg mg NNP cord-022526-j9kg00qf 369 15 / / SYM cord-022526-j9kg00qf 369 16 dl dl NN cord-022526-j9kg00qf 369 17 at at IN cord-022526-j9kg00qf 369 18 60 60 CD cord-022526-j9kg00qf 369 19 to to TO cord-022526-j9kg00qf 369 20 120 120 CD cord-022526-j9kg00qf 369 21 minutes minute NNS cord-022526-j9kg00qf 369 22 after after IN cord-022526-j9kg00qf 369 23 dosing dose VBG cord-022526-j9kg00qf 369 24 . . . cord-022526-j9kg00qf 370 1 62 62 CD cord-022526-j9kg00qf 371 1 Decreased decrease VBD cord-022526-j9kg00qf 371 2 xylose xylose NN cord-022526-j9kg00qf 371 3 absorption absorption NN cord-022526-j9kg00qf 371 4 can can MD cord-022526-j9kg00qf 371 5 occur occur VB cord-022526-j9kg00qf 371 6 in in IN cord-022526-j9kg00qf 371 7 horses horse NNS cord-022526-j9kg00qf 371 8 with with IN cord-022526-j9kg00qf 371 9 inflammatory inflammatory JJ cord-022526-j9kg00qf 371 10 bowel bowel NN cord-022526-j9kg00qf 371 11 disease disease NN cord-022526-j9kg00qf 371 12 , , , cord-022526-j9kg00qf 371 13 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 371 14 , , , cord-022526-j9kg00qf 371 15 multisystemic multisystemic NNP cord-022526-j9kg00qf 371 16 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 371 17 epitheliotropic epitheliotropic NNP cord-022526-j9kg00qf 371 18 disease disease NN cord-022526-j9kg00qf 371 19 , , , cord-022526-j9kg00qf 371 20 cyathostomiasis cyathostomiasis NNP cord-022526-j9kg00qf 371 21 , , , cord-022526-j9kg00qf 371 22 extensive extensive JJ cord-022526-j9kg00qf 371 23 small small JJ cord-022526-j9kg00qf 371 24 intestinal intestinal JJ cord-022526-j9kg00qf 371 25 resections resection NNS cord-022526-j9kg00qf 371 26 , , , cord-022526-j9kg00qf 371 27 and and CC cord-022526-j9kg00qf 371 28 any any DT cord-022526-j9kg00qf 371 29 cause cause NN cord-022526-j9kg00qf 371 30 of of IN cord-022526-j9kg00qf 371 31 villous villous JJ cord-022526-j9kg00qf 371 32 atrophy atrophy NN cord-022526-j9kg00qf 371 33 . . . cord-022526-j9kg00qf 372 1 61 61 CD cord-022526-j9kg00qf 372 2 Maldigestion Maldigestion NNP cord-022526-j9kg00qf 372 3 is be VBZ cord-022526-j9kg00qf 372 4 a a DT cord-022526-j9kg00qf 372 5 common common JJ cord-022526-j9kg00qf 372 6 occurrence occurrence NN cord-022526-j9kg00qf 372 7 in in IN cord-022526-j9kg00qf 372 8 foals foal NNS cord-022526-j9kg00qf 372 9 with with IN cord-022526-j9kg00qf 372 10 diarrhea diarrhea NN cord-022526-j9kg00qf 372 11 . . . cord-022526-j9kg00qf 373 1 Bacteria Bacteria NNS cord-022526-j9kg00qf 373 2 ( ( -LRB- cord-022526-j9kg00qf 373 3 especially especially RB cord-022526-j9kg00qf 373 4 Clostridium Clostridium NNP cord-022526-j9kg00qf 373 5 sp sp NN cord-022526-j9kg00qf 373 6 . . . cord-022526-j9kg00qf 373 7 ) ) -RRB- cord-022526-j9kg00qf 373 8 and and CC cord-022526-j9kg00qf 373 9 viruses virus NNS cord-022526-j9kg00qf 373 10 ( ( -LRB- cord-022526-j9kg00qf 373 11 especially especially RB cord-022526-j9kg00qf 373 12 rotavirus rotavirus JJ cord-022526-j9kg00qf 373 13 or or CC cord-022526-j9kg00qf 373 14 coronavirus coronavirus NN cord-022526-j9kg00qf 373 15 ) ) -RRB- cord-022526-j9kg00qf 373 16 may may MD cord-022526-j9kg00qf 373 17 invade invade VB cord-022526-j9kg00qf 373 18 and and CC cord-022526-j9kg00qf 373 19 destroy destroy VB cord-022526-j9kg00qf 373 20 the the DT cord-022526-j9kg00qf 373 21 villous villous JJ cord-022526-j9kg00qf 373 22 epithelial epithelial JJ cord-022526-j9kg00qf 373 23 cells cell NNS cord-022526-j9kg00qf 373 24 that that WDT cord-022526-j9kg00qf 373 25 manufacture manufacture VBP cord-022526-j9kg00qf 373 26 lactase lactase NN cord-022526-j9kg00qf 373 27 and and CC cord-022526-j9kg00qf 373 28 other other JJ cord-022526-j9kg00qf 373 29 disaccharidases disaccharidase NNS cord-022526-j9kg00qf 373 30 , , , cord-022526-j9kg00qf 373 31 resulting result VBG cord-022526-j9kg00qf 373 32 in in IN cord-022526-j9kg00qf 373 33 an an DT cord-022526-j9kg00qf 373 34 inability inability NN cord-022526-j9kg00qf 373 35 to to TO cord-022526-j9kg00qf 373 36 digest digest VB cord-022526-j9kg00qf 373 37 lactose lactose NN cord-022526-j9kg00qf 373 38 . . . cord-022526-j9kg00qf 374 1 In in IN cord-022526-j9kg00qf 374 2 this this DT cord-022526-j9kg00qf 374 3 case case NN cord-022526-j9kg00qf 374 4 , , , cord-022526-j9kg00qf 374 5 continued continue VBD cord-022526-j9kg00qf 374 6 ingestion ingestion NN cord-022526-j9kg00qf 374 7 of of IN cord-022526-j9kg00qf 374 8 the the DT cord-022526-j9kg00qf 374 9 mare mare NN cord-022526-j9kg00qf 374 10 's 's POS cord-022526-j9kg00qf 374 11 milk milk NN cord-022526-j9kg00qf 374 12 may may MD cord-022526-j9kg00qf 374 13 cause cause VB cord-022526-j9kg00qf 374 14 an an DT cord-022526-j9kg00qf 374 15 osmotic osmotic JJ cord-022526-j9kg00qf 374 16 diarrhea diarrhea NN cord-022526-j9kg00qf 374 17 , , , cord-022526-j9kg00qf 374 18 which which WDT cord-022526-j9kg00qf 374 19 may may MD cord-022526-j9kg00qf 374 20 exacerbate exacerbate VB cord-022526-j9kg00qf 374 21 the the DT cord-022526-j9kg00qf 374 22 underlying underlie VBG cord-022526-j9kg00qf 374 23 enterocolitis enterocolitis NN cord-022526-j9kg00qf 374 24 . . . cord-022526-j9kg00qf 375 1 One one PRP cord-022526-j9kg00qf 375 2 can can MD cord-022526-j9kg00qf 375 3 perform perform VB cord-022526-j9kg00qf 375 4 lactose lactose JJ cord-022526-j9kg00qf 375 5 tolerance tolerance NN cord-022526-j9kg00qf 375 6 testing testing NN cord-022526-j9kg00qf 375 7 to to TO cord-022526-j9kg00qf 375 8 assess assess VB cord-022526-j9kg00qf 375 9 the the DT cord-022526-j9kg00qf 375 10 degree degree NN cord-022526-j9kg00qf 375 11 of of IN cord-022526-j9kg00qf 375 12 maldigestion maldigestion NN cord-022526-j9kg00qf 375 13 . . . cord-022526-j9kg00qf 376 1 One one PRP cord-022526-j9kg00qf 376 2 administers administer VBZ cord-022526-j9kg00qf 376 3 D d NN cord-022526-j9kg00qf 376 4 - - HYPH cord-022526-j9kg00qf 376 5 lactose lactose NN cord-022526-j9kg00qf 376 6 at at IN cord-022526-j9kg00qf 376 7 1 1 CD cord-022526-j9kg00qf 376 8 g g NN cord-022526-j9kg00qf 376 9 / / SYM cord-022526-j9kg00qf 376 10 kg kg NN cord-022526-j9kg00qf 376 11 as as IN cord-022526-j9kg00qf 376 12 a a DT cord-022526-j9kg00qf 376 13 20 20 CD cord-022526-j9kg00qf 376 14 % % NN cord-022526-j9kg00qf 376 15 solution solution NN cord-022526-j9kg00qf 376 16 via via IN cord-022526-j9kg00qf 376 17 nasogastric nasogastric NN cord-022526-j9kg00qf 376 18 tube tube NN cord-022526-j9kg00qf 376 19 and and CC cord-022526-j9kg00qf 376 20 measures measure NNS cord-022526-j9kg00qf 376 21 glucose glucose NN cord-022526-j9kg00qf 376 22 concentrations concentration NNS cord-022526-j9kg00qf 376 23 in in IN cord-022526-j9kg00qf 376 24 the the DT cord-022526-j9kg00qf 376 25 blood blood NN cord-022526-j9kg00qf 376 26 at at IN cord-022526-j9kg00qf 376 27 0 0 CD cord-022526-j9kg00qf 376 28 , , , cord-022526-j9kg00qf 376 29 30 30 CD cord-022526-j9kg00qf 376 30 , , , cord-022526-j9kg00qf 376 31 60 60 CD cord-022526-j9kg00qf 376 32 , , , cord-022526-j9kg00qf 376 33 90 90 CD cord-022526-j9kg00qf 376 34 , , , cord-022526-j9kg00qf 376 35 120 120 CD cord-022526-j9kg00qf 376 36 , , , cord-022526-j9kg00qf 376 37 150 150 CD cord-022526-j9kg00qf 376 38 , , , cord-022526-j9kg00qf 376 39 180 180 CD cord-022526-j9kg00qf 376 40 , , , cord-022526-j9kg00qf 376 41 210 210 CD cord-022526-j9kg00qf 376 42 , , , cord-022526-j9kg00qf 376 43 and and CC cord-022526-j9kg00qf 376 44 240 240 CD cord-022526-j9kg00qf 376 45 minutes minute NNS cord-022526-j9kg00qf 376 46 . . . cord-022526-j9kg00qf 377 1 A a DT cord-022526-j9kg00qf 377 2 normal normal JJ cord-022526-j9kg00qf 377 3 curve curve NN cord-022526-j9kg00qf 377 4 shows show VBZ cord-022526-j9kg00qf 377 5 doubling double VBG cord-022526-j9kg00qf 377 6 of of IN cord-022526-j9kg00qf 377 7 glucose glucose NN cord-022526-j9kg00qf 377 8 levels level NNS cord-022526-j9kg00qf 377 9 compared compare VBN cord-022526-j9kg00qf 377 10 with with IN cord-022526-j9kg00qf 377 11 baseline baseline NN cord-022526-j9kg00qf 377 12 by by IN cord-022526-j9kg00qf 377 13 60 60 CD cord-022526-j9kg00qf 377 14 minutes minute NNS cord-022526-j9kg00qf 377 15 after after IN cord-022526-j9kg00qf 377 16 administration administration NN cord-022526-j9kg00qf 377 17 . . . cord-022526-j9kg00qf 378 1 63 63 CD cord-022526-j9kg00qf 378 2 accurate accurate JJ cord-022526-j9kg00qf 378 3 measurement measurement NN cord-022526-j9kg00qf 378 4 of of IN cord-022526-j9kg00qf 378 5 gastric gastric JJ cord-022526-j9kg00qf 378 6 emptying emptying NN cord-022526-j9kg00qf 378 7 can can MD cord-022526-j9kg00qf 378 8 be be VB cord-022526-j9kg00qf 378 9 difficult difficult JJ cord-022526-j9kg00qf 378 10 to to TO cord-022526-j9kg00qf 378 11 assess assess VB cord-022526-j9kg00qf 378 12 . . . cord-022526-j9kg00qf 379 1 Several several JJ cord-022526-j9kg00qf 379 2 methods method NNS cord-022526-j9kg00qf 379 3 are be VBP cord-022526-j9kg00qf 379 4 currently currently RB cord-022526-j9kg00qf 379 5 available available JJ cord-022526-j9kg00qf 379 6 . . . cord-022526-j9kg00qf 380 1 Multiple multiple JJ cord-022526-j9kg00qf 380 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 380 3 imaging imaging NN cord-022526-j9kg00qf 380 4 techniques technique NNS cord-022526-j9kg00qf 380 5 have have VBP cord-022526-j9kg00qf 380 6 been be VBN cord-022526-j9kg00qf 380 7 used use VBN cord-022526-j9kg00qf 380 8 to to TO cord-022526-j9kg00qf 380 9 study study VB cord-022526-j9kg00qf 380 10 gastric gastric JJ cord-022526-j9kg00qf 380 11 emptying emptying NN cord-022526-j9kg00qf 380 12 times time NNS cord-022526-j9kg00qf 380 13 . . . cord-022526-j9kg00qf 381 1 One one PRP cord-022526-j9kg00qf 381 2 can can MD cord-022526-j9kg00qf 381 3 use use VB cord-022526-j9kg00qf 381 4 contrast contrast NN cord-022526-j9kg00qf 381 5 radiography radiography NN cord-022526-j9kg00qf 381 6 to to TO cord-022526-j9kg00qf 381 7 assess assess VB cord-022526-j9kg00qf 381 8 gastric gastric JJ cord-022526-j9kg00qf 381 9 emptying emptying NN cord-022526-j9kg00qf 381 10 in in IN cord-022526-j9kg00qf 381 11 foals foal NNS cord-022526-j9kg00qf 381 12 . . . cord-022526-j9kg00qf 382 1 In in IN cord-022526-j9kg00qf 382 2 the the DT cord-022526-j9kg00qf 382 3 normal normal JJ cord-022526-j9kg00qf 382 4 foal foal NN cord-022526-j9kg00qf 382 5 , , , cord-022526-j9kg00qf 382 6 barium barium NN cord-022526-j9kg00qf 382 7 remains remain VBZ cord-022526-j9kg00qf 382 8 in in IN cord-022526-j9kg00qf 382 9 the the DT cord-022526-j9kg00qf 382 10 stomach stomach NN cord-022526-j9kg00qf 382 11 for for IN cord-022526-j9kg00qf 382 12 varying vary VBG cord-022526-j9kg00qf 382 13 amounts amount NNS cord-022526-j9kg00qf 382 14 of of IN cord-022526-j9kg00qf 382 15 time time NN cord-022526-j9kg00qf 382 16 , , , cord-022526-j9kg00qf 382 17 but but CC cord-022526-j9kg00qf 382 18 a a DT cord-022526-j9kg00qf 382 19 significant significant JJ cord-022526-j9kg00qf 382 20 amount amount NN cord-022526-j9kg00qf 382 21 should should MD cord-022526-j9kg00qf 382 22 be be VB cord-022526-j9kg00qf 382 23 gone go VBN cord-022526-j9kg00qf 382 24 within within IN cord-022526-j9kg00qf 382 25 2 2 CD cord-022526-j9kg00qf 382 26 hours hour NNS cord-022526-j9kg00qf 382 27 . . . cord-022526-j9kg00qf 383 1 44 44 CD cord-022526-j9kg00qf 383 2 Gastric gastric JJ cord-022526-j9kg00qf 383 3 emptying emptying NN cord-022526-j9kg00qf 383 4 of of IN cord-022526-j9kg00qf 383 5 solid solid JJ cord-022526-j9kg00qf 383 6 , , , cord-022526-j9kg00qf 383 7 nondigestible nondigestible JJ cord-022526-j9kg00qf 383 8 , , , cord-022526-j9kg00qf 383 9 radiopaque radiopaque JJ cord-022526-j9kg00qf 383 10 markers marker NNS cord-022526-j9kg00qf 383 11 also also RB cord-022526-j9kg00qf 383 12 has have VBZ cord-022526-j9kg00qf 383 13 been be VBN cord-022526-j9kg00qf 383 14 used use VBN cord-022526-j9kg00qf 383 15 in in IN cord-022526-j9kg00qf 383 16 adult adult NN cord-022526-j9kg00qf 383 17 horses horse NNS cord-022526-j9kg00qf 383 18 and and CC cord-022526-j9kg00qf 383 19 ponies pony NNS cord-022526-j9kg00qf 383 20 , , , cord-022526-j9kg00qf 383 21 but but CC cord-022526-j9kg00qf 383 22 the the DT cord-022526-j9kg00qf 383 23 results result NNS cord-022526-j9kg00qf 383 24 were be VBD cord-022526-j9kg00qf 383 25 variable variable JJ cord-022526-j9kg00qf 383 26 and and CC cord-022526-j9kg00qf 383 27 unpredictable unpredictable JJ cord-022526-j9kg00qf 383 28 even even RB cord-022526-j9kg00qf 383 29 in in IN cord-022526-j9kg00qf 383 30 the the DT cord-022526-j9kg00qf 383 31 normal normal JJ cord-022526-j9kg00qf 383 32 horse horse NN cord-022526-j9kg00qf 383 33 . . . cord-022526-j9kg00qf 384 1 64 64 CD cord-022526-j9kg00qf 384 2 Nuclear nuclear JJ cord-022526-j9kg00qf 384 3 scintigraphy scintigraphy NN cord-022526-j9kg00qf 384 4 is be VBZ cord-022526-j9kg00qf 384 5 used use VBN cord-022526-j9kg00qf 384 6 commonly commonly RB cord-022526-j9kg00qf 384 7 in in IN cord-022526-j9kg00qf 384 8 human human JJ cord-022526-j9kg00qf 384 9 beings being NNS cord-022526-j9kg00qf 384 10 to to TO cord-022526-j9kg00qf 384 11 measure measure VB cord-022526-j9kg00qf 384 12 gastric gastric JJ cord-022526-j9kg00qf 384 13 emptying emptying NN cord-022526-j9kg00qf 384 14 and and CC cord-022526-j9kg00qf 384 15 can can MD cord-022526-j9kg00qf 384 16 be be VB cord-022526-j9kg00qf 384 17 used use VBN cord-022526-j9kg00qf 384 18 in in IN cord-022526-j9kg00qf 384 19 horses horse NNS cord-022526-j9kg00qf 384 20 where where WRB cord-022526-j9kg00qf 384 21 available available JJ cord-022526-j9kg00qf 384 22 . . . cord-022526-j9kg00qf 385 1 This this DT cord-022526-j9kg00qf 385 2 technique technique NN cord-022526-j9kg00qf 385 3 requires require VBZ cord-022526-j9kg00qf 385 4 oral oral JJ cord-022526-j9kg00qf 385 5 administration administration NN cord-022526-j9kg00qf 385 6 of of IN cord-022526-j9kg00qf 385 7 99 99 CD cord-022526-j9kg00qf 385 8 m m NNP cord-022526-j9kg00qf 385 9 Tc Tc NNP cord-022526-j9kg00qf 385 10 pentenate pentenate NNP cord-022526-j9kg00qf 385 11 ( ( -LRB- cord-022526-j9kg00qf 385 12 10 10 CD cord-022526-j9kg00qf 385 13 mCi mCi NNS cord-022526-j9kg00qf 385 14 ) ) -RRB- cord-022526-j9kg00qf 385 15 , , , cord-022526-j9kg00qf 385 16 and and CC cord-022526-j9kg00qf 385 17 serial serial JJ cord-022526-j9kg00qf 385 18 images image NNS cord-022526-j9kg00qf 385 19 taken take VBN cord-022526-j9kg00qf 385 20 of of IN cord-022526-j9kg00qf 385 21 the the DT cord-022526-j9kg00qf 385 22 cranial cranial JJ cord-022526-j9kg00qf 385 23 abdomen abdomen NN cord-022526-j9kg00qf 385 24 . . . cord-022526-j9kg00qf 386 1 The the DT cord-022526-j9kg00qf 386 2 tracer tracer NN cord-022526-j9kg00qf 386 3 is be VBZ cord-022526-j9kg00qf 386 4 usually usually RB cord-022526-j9kg00qf 386 5 not not RB cord-022526-j9kg00qf 386 6 visible visible JJ cord-022526-j9kg00qf 386 7 60 60 CD cord-022526-j9kg00qf 386 8 minutes minute NNS cord-022526-j9kg00qf 386 9 after after IN cord-022526-j9kg00qf 386 10 administration administration NN cord-022526-j9kg00qf 386 11 in in IN cord-022526-j9kg00qf 386 12 normal normal JJ cord-022526-j9kg00qf 386 13 horses horse NNS cord-022526-j9kg00qf 386 14 . . . cord-022526-j9kg00qf 387 1 58 58 CD cord-022526-j9kg00qf 388 1 Alternatively alternatively RB cord-022526-j9kg00qf 388 2 , , , cord-022526-j9kg00qf 388 3 if if IN cord-022526-j9kg00qf 388 4 nuclear nuclear JJ cord-022526-j9kg00qf 388 5 scintigraphy scintigraphy NN cord-022526-j9kg00qf 388 6 is be VBZ cord-022526-j9kg00qf 388 7 not not RB cord-022526-j9kg00qf 388 8 available available JJ cord-022526-j9kg00qf 388 9 , , , cord-022526-j9kg00qf 388 10 one one PRP cord-022526-j9kg00qf 388 11 can can MD cord-022526-j9kg00qf 388 12 use use VB cord-022526-j9kg00qf 388 13 acetaminophen acetaminophen NN cord-022526-j9kg00qf 388 14 absorption absorption NN cord-022526-j9kg00qf 388 15 testing testing NN cord-022526-j9kg00qf 388 16 as as IN cord-022526-j9kg00qf 388 17 an an DT cord-022526-j9kg00qf 388 18 indirect indirect JJ cord-022526-j9kg00qf 388 19 determination determination NN cord-022526-j9kg00qf 388 20 of of IN cord-022526-j9kg00qf 388 21 gastric gastric JJ cord-022526-j9kg00qf 388 22 emptying emptying NN cord-022526-j9kg00qf 388 23 . . . cord-022526-j9kg00qf 389 1 58 58 CD cord-022526-j9kg00qf 389 2 , , , cord-022526-j9kg00qf 389 3 65 65 CD cord-022526-j9kg00qf 389 4 One one CD cord-022526-j9kg00qf 389 5 performs perform VBZ cord-022526-j9kg00qf 389 6 this this DT cord-022526-j9kg00qf 389 7 test test NN cord-022526-j9kg00qf 389 8 by by IN cord-022526-j9kg00qf 389 9 administering administer VBG cord-022526-j9kg00qf 389 10 20 20 CD cord-022526-j9kg00qf 389 11 mg mg NNP cord-022526-j9kg00qf 389 12 / / SYM cord-022526-j9kg00qf 389 13 kg kg NNS cord-022526-j9kg00qf 389 14 of of IN cord-022526-j9kg00qf 389 15 acetaminophen acetaminophen NN cord-022526-j9kg00qf 389 16 orally orally RB cord-022526-j9kg00qf 389 17 and and CC cord-022526-j9kg00qf 389 18 measuring measure VBG cord-022526-j9kg00qf 389 19 subsequent subsequent JJ cord-022526-j9kg00qf 389 20 blood blood NN cord-022526-j9kg00qf 389 21 values value NNS cord-022526-j9kg00qf 389 22 and and CC cord-022526-j9kg00qf 389 23 calculating calculate VBG cord-022526-j9kg00qf 389 24 the the DT cord-022526-j9kg00qf 389 25 time time NN cord-022526-j9kg00qf 389 26 to to TO cord-022526-j9kg00qf 389 27 reach reach VB cord-022526-j9kg00qf 389 28 maximum maximum JJ cord-022526-j9kg00qf 389 29 serum serum NN cord-022526-j9kg00qf 389 30 concentrations concentration NNS cord-022526-j9kg00qf 389 31 and and CC cord-022526-j9kg00qf 389 32 the the DT cord-022526-j9kg00qf 389 33 absorption absorption NN cord-022526-j9kg00qf 389 34 constant constant JJ cord-022526-j9kg00qf 389 35 . . . cord-022526-j9kg00qf 390 1 In in IN cord-022526-j9kg00qf 390 2 human human JJ cord-022526-j9kg00qf 390 3 beings being NNS cord-022526-j9kg00qf 390 4 , , , cord-022526-j9kg00qf 390 5 the the DT cord-022526-j9kg00qf 390 6 proximal proximal JJ cord-022526-j9kg00qf 390 7 small small JJ cord-022526-j9kg00qf 390 8 intestine intestine NN cord-022526-j9kg00qf 390 9 absorbs absorb VBZ cord-022526-j9kg00qf 390 10 almost almost RB cord-022526-j9kg00qf 390 11 all all DT cord-022526-j9kg00qf 390 12 of of IN cord-022526-j9kg00qf 390 13 the the DT cord-022526-j9kg00qf 390 14 acetaminophen acetaminophen NN cord-022526-j9kg00qf 390 15 . . . cord-022526-j9kg00qf 391 1 66 66 CD cord-022526-j9kg00qf 392 1 The the DT cord-022526-j9kg00qf 392 2 median median JJ cord-022526-j9kg00qf 392 3 time time NN cord-022526-j9kg00qf 392 4 to to TO cord-022526-j9kg00qf 392 5 reach reach VB cord-022526-j9kg00qf 392 6 peak peak NN cord-022526-j9kg00qf 392 7 plasma plasma NN cord-022526-j9kg00qf 392 8 levels level NNS cord-022526-j9kg00qf 392 9 using use VBG cord-022526-j9kg00qf 392 10 acetaminophen acetaminophen JJ cord-022526-j9kg00qf 392 11 absorption absorption NN cord-022526-j9kg00qf 392 12 in in IN cord-022526-j9kg00qf 392 13 horses horse NNS cord-022526-j9kg00qf 392 14 was be VBD cord-022526-j9kg00qf 392 15 47.7 47.7 CD cord-022526-j9kg00qf 392 16 minutes minute NNS cord-022526-j9kg00qf 392 17 . . . cord-022526-j9kg00qf 393 1 58 58 CD cord-022526-j9kg00qf 393 2 One one CD cord-022526-j9kg00qf 393 3 often often RB cord-022526-j9kg00qf 393 4 requires require VBZ cord-022526-j9kg00qf 393 5 histopathologic histopathologic JJ cord-022526-j9kg00qf 393 6 examination examination NN cord-022526-j9kg00qf 393 7 of of IN cord-022526-j9kg00qf 393 8 tissues tissue NNS cord-022526-j9kg00qf 393 9 from from IN cord-022526-j9kg00qf 393 10 the the DT cord-022526-j9kg00qf 393 11 intestine intestine NN cord-022526-j9kg00qf 393 12 to to TO cord-022526-j9kg00qf 393 13 diagnose diagnose VB cord-022526-j9kg00qf 393 14 chronic chronic JJ cord-022526-j9kg00qf 393 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 393 16 , , , cord-022526-j9kg00qf 393 17 infiltrative infiltrative JJ cord-022526-j9kg00qf 393 18 , , , cord-022526-j9kg00qf 393 19 or or CC cord-022526-j9kg00qf 393 20 neoplastic neoplastic JJ cord-022526-j9kg00qf 393 21 conditions condition NNS cord-022526-j9kg00qf 393 22 , , , cord-022526-j9kg00qf 393 23 and and CC cord-022526-j9kg00qf 393 24 such such JJ cord-022526-j9kg00qf 393 25 examination examination NN cord-022526-j9kg00qf 393 26 can can MD cord-022526-j9kg00qf 393 27 be be VB cord-022526-j9kg00qf 393 28 useful useful JJ cord-022526-j9kg00qf 393 29 in in IN cord-022526-j9kg00qf 393 30 evaluating evaluate VBG cord-022526-j9kg00qf 393 31 the the DT cord-022526-j9kg00qf 393 32 extent extent NN cord-022526-j9kg00qf 393 33 of of IN cord-022526-j9kg00qf 393 34 injury injury NN cord-022526-j9kg00qf 393 35 after after IN cord-022526-j9kg00qf 393 36 obstruction obstruction NN cord-022526-j9kg00qf 393 37 or or CC cord-022526-j9kg00qf 393 38 ischemia ischemia NN cord-022526-j9kg00qf 393 39 . . . cord-022526-j9kg00qf 394 1 Rectal rectal JJ cord-022526-j9kg00qf 394 2 mucosal mucosal JJ cord-022526-j9kg00qf 394 3 biopsies biopsy NNS cord-022526-j9kg00qf 394 4 are be VBP cord-022526-j9kg00qf 394 5 easy easy JJ cord-022526-j9kg00qf 394 6 to to TO cord-022526-j9kg00qf 394 7 collect collect VB cord-022526-j9kg00qf 394 8 with with IN cord-022526-j9kg00qf 394 9 few few JJ cord-022526-j9kg00qf 394 10 complications complication NNS cord-022526-j9kg00qf 394 11 . . . cord-022526-j9kg00qf 395 1 However however RB cord-022526-j9kg00qf 395 2 , , , cord-022526-j9kg00qf 395 3 to to TO cord-022526-j9kg00qf 395 4 collect collect VB cord-022526-j9kg00qf 395 5 a a DT cord-022526-j9kg00qf 395 6 full full JJ cord-022526-j9kg00qf 395 7 - - HYPH cord-022526-j9kg00qf 395 8 thickness thickness NN cord-022526-j9kg00qf 395 9 biopsy biopsy NN cord-022526-j9kg00qf 395 10 of of IN cord-022526-j9kg00qf 395 11 the the DT cord-022526-j9kg00qf 395 12 intestine intestine NN cord-022526-j9kg00qf 395 13 requires require VBZ cord-022526-j9kg00qf 395 14 a a DT cord-022526-j9kg00qf 395 15 surgical surgical JJ cord-022526-j9kg00qf 395 16 approach approach NN cord-022526-j9kg00qf 395 17 ( ( -LRB- cord-022526-j9kg00qf 395 18 flank flank NN cord-022526-j9kg00qf 395 19 or or CC cord-022526-j9kg00qf 395 20 ventral ventral JJ cord-022526-j9kg00qf 395 21 midline midline JJ cord-022526-j9kg00qf 395 22 approach approach NN cord-022526-j9kg00qf 395 23 ) ) -RRB- cord-022526-j9kg00qf 395 24 . . . cord-022526-j9kg00qf 396 1 Laparoscopy Laparoscopy NNP cord-022526-j9kg00qf 396 2 offers offer VBZ cord-022526-j9kg00qf 396 3 a a DT cord-022526-j9kg00qf 396 4 safer safe JJR cord-022526-j9kg00qf 396 5 technique technique NN cord-022526-j9kg00qf 396 6 to to TO cord-022526-j9kg00qf 396 7 observe observe VB cord-022526-j9kg00qf 396 8 the the DT cord-022526-j9kg00qf 396 9 large large JJ cord-022526-j9kg00qf 396 10 intestine intestine NN cord-022526-j9kg00qf 396 11 and and CC cord-022526-j9kg00qf 396 12 other other JJ cord-022526-j9kg00qf 396 13 abdominal abdominal JJ cord-022526-j9kg00qf 396 14 structures structure NNS cord-022526-j9kg00qf 396 15 . . . cord-022526-j9kg00qf 397 1 67 67 CD cord-022526-j9kg00qf 398 1 One one PRP cord-022526-j9kg00qf 398 2 can can MD cord-022526-j9kg00qf 398 3 obtain obtain VB cord-022526-j9kg00qf 398 4 biopsies biopsy NNS cord-022526-j9kg00qf 398 5 of of IN cord-022526-j9kg00qf 398 6 masses masse NNS cord-022526-j9kg00qf 398 7 , , , cord-022526-j9kg00qf 398 8 lymph lymph NN cord-022526-j9kg00qf 398 9 nodes node NNS cord-022526-j9kg00qf 398 10 , , , cord-022526-j9kg00qf 398 11 mesentery mesentery NN cord-022526-j9kg00qf 398 12 , , , cord-022526-j9kg00qf 398 13 or or CC cord-022526-j9kg00qf 398 14 intestinal intestinal JJ cord-022526-j9kg00qf 398 15 serosa serosa NN cord-022526-j9kg00qf 398 16 via via IN cord-022526-j9kg00qf 398 17 laparoscopy laparoscopy NN cord-022526-j9kg00qf 398 18 and and CC cord-022526-j9kg00qf 398 19 mucosal mucosal JJ cord-022526-j9kg00qf 398 20 biopsies biopsy NNS cord-022526-j9kg00qf 398 21 of of IN cord-022526-j9kg00qf 398 22 the the DT cord-022526-j9kg00qf 398 23 upper upper JJ cord-022526-j9kg00qf 398 24 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 398 25 tract tract NN cord-022526-j9kg00qf 398 26 via via IN cord-022526-j9kg00qf 398 27 endoscopy endoscopy NN cord-022526-j9kg00qf 398 28 . . . cord-022526-j9kg00qf 399 1 Other other JJ cord-022526-j9kg00qf 399 2 diagnostics diagnostic NNS cord-022526-j9kg00qf 399 3 , , , cord-022526-j9kg00qf 399 4 specifically specifically RB cord-022526-j9kg00qf 399 5 laparoscopy laparoscopy RB cord-022526-j9kg00qf 399 6 and and CC cord-022526-j9kg00qf 399 7 computed compute VBD cord-022526-j9kg00qf 399 8 tomography tomography NN cord-022526-j9kg00qf 399 9 , , , cord-022526-j9kg00qf 399 10 are be VBP cord-022526-j9kg00qf 399 11 available available JJ cord-022526-j9kg00qf 399 12 but but CC cord-022526-j9kg00qf 399 13 require require VB cord-022526-j9kg00qf 399 14 specialized specialized JJ cord-022526-j9kg00qf 399 15 equipment equipment NN cord-022526-j9kg00qf 399 16 and and CC cord-022526-j9kg00qf 399 17 personnel personnel NNS cord-022526-j9kg00qf 399 18 with with IN cord-022526-j9kg00qf 399 19 specific specific JJ cord-022526-j9kg00qf 399 20 training training NN cord-022526-j9kg00qf 399 21 . . . cord-022526-j9kg00qf 400 1 Flexible flexible JJ cord-022526-j9kg00qf 400 2 or or CC cord-022526-j9kg00qf 400 3 rigid rigid JJ cord-022526-j9kg00qf 400 4 endoscopes endoscope NNS cord-022526-j9kg00qf 400 5 used use VBN cord-022526-j9kg00qf 400 6 for for IN cord-022526-j9kg00qf 400 7 laparoscopic laparoscopic JJ cord-022526-j9kg00qf 400 8 evaluation evaluation NN cord-022526-j9kg00qf 400 9 of of IN cord-022526-j9kg00qf 400 10 the the DT cord-022526-j9kg00qf 400 11 abdomen abdoman NNS cord-022526-j9kg00qf 400 12 allow allow VB cord-022526-j9kg00qf 400 13 for for IN cord-022526-j9kg00qf 400 14 visualization visualization NN cord-022526-j9kg00qf 400 15 of of IN cord-022526-j9kg00qf 400 16 visceral visceral JJ cord-022526-j9kg00qf 400 17 organs organ NNS cord-022526-j9kg00qf 400 18 and and CC cord-022526-j9kg00qf 400 19 potentially potentially RB cord-022526-j9kg00qf 400 20 for for IN cord-022526-j9kg00qf 400 21 collection collection NN cord-022526-j9kg00qf 400 22 of of IN cord-022526-j9kg00qf 400 23 biopsy biopsy NN cord-022526-j9kg00qf 400 24 material material NN cord-022526-j9kg00qf 400 25 from from IN cord-022526-j9kg00qf 400 26 masses masse NNS cord-022526-j9kg00qf 400 27 or or CC cord-022526-j9kg00qf 400 28 organs organ NNS cord-022526-j9kg00qf 400 29 . . . cord-022526-j9kg00qf 401 1 Full full JJ cord-022526-j9kg00qf 401 2 - - HYPH cord-022526-j9kg00qf 401 3 thickness thickness NN cord-022526-j9kg00qf 401 4 biopsies biopsy NNS cord-022526-j9kg00qf 401 5 of of IN cord-022526-j9kg00qf 401 6 the the DT cord-022526-j9kg00qf 401 7 intestines intestine NNS cord-022526-j9kg00qf 401 8 are be VBP cord-022526-j9kg00qf 401 9 not not RB cord-022526-j9kg00qf 401 10 routinely routinely RB cord-022526-j9kg00qf 401 11 possible possible JJ cord-022526-j9kg00qf 401 12 through through IN cord-022526-j9kg00qf 401 13 the the DT cord-022526-j9kg00qf 401 14 laparoscope laparoscope NN cord-022526-j9kg00qf 401 15 and and CC cord-022526-j9kg00qf 401 16 usually usually RB cord-022526-j9kg00qf 401 17 require require VBP cord-022526-j9kg00qf 401 18 flank flank NN cord-022526-j9kg00qf 401 19 or or CC cord-022526-j9kg00qf 401 20 ventral ventral JJ cord-022526-j9kg00qf 401 21 midline midline JJ cord-022526-j9kg00qf 401 22 laparotomy laparotomy NN cord-022526-j9kg00qf 401 23 . . . cord-022526-j9kg00qf 402 1 The the DT cord-022526-j9kg00qf 402 2 laparoscopic laparoscopic JJ cord-022526-j9kg00qf 402 3 procedure procedure NN cord-022526-j9kg00qf 402 4 can can MD cord-022526-j9kg00qf 402 5 be be VB cord-022526-j9kg00qf 402 6 done do VBN cord-022526-j9kg00qf 402 7 in in IN cord-022526-j9kg00qf 402 8 the the DT cord-022526-j9kg00qf 402 9 standing standing NN cord-022526-j9kg00qf 402 10 or or CC cord-022526-j9kg00qf 402 11 recumbent recumbent JJ cord-022526-j9kg00qf 402 12 horse horse NN cord-022526-j9kg00qf 402 13 . . . cord-022526-j9kg00qf 403 1 Advantages advantage NNS cord-022526-j9kg00qf 403 2 of of IN cord-022526-j9kg00qf 403 3 this this DT cord-022526-j9kg00qf 403 4 technique technique NN cord-022526-j9kg00qf 403 5 over over IN cord-022526-j9kg00qf 403 6 a a DT cord-022526-j9kg00qf 403 7 flank flank NN cord-022526-j9kg00qf 403 8 or or CC cord-022526-j9kg00qf 403 9 ventral ventral JJ cord-022526-j9kg00qf 403 10 midline midline JJ cord-022526-j9kg00qf 403 11 celiotomy celiotomy NN cord-022526-j9kg00qf 403 12 include include VBP cord-022526-j9kg00qf 403 13 smaller small JJR cord-022526-j9kg00qf 403 14 incisions incision NNS cord-022526-j9kg00qf 403 15 , , , cord-022526-j9kg00qf 403 16 less less RBR cord-022526-j9kg00qf 403 17 healing healing NN cord-022526-j9kg00qf 403 18 time time NN cord-022526-j9kg00qf 403 19 , , , cord-022526-j9kg00qf 403 20 and and CC cord-022526-j9kg00qf 403 21 less less JJR cord-022526-j9kg00qf 403 22 procedure procedure NN cord-022526-j9kg00qf 403 23 time time NN cord-022526-j9kg00qf 403 24 . . . cord-022526-j9kg00qf 404 1 Disadvantages disadvantage NNS cord-022526-j9kg00qf 404 2 include include VBP cord-022526-j9kg00qf 404 3 the the DT cord-022526-j9kg00qf 404 4 large large JJ cord-022526-j9kg00qf 404 5 amount amount NN cord-022526-j9kg00qf 404 6 of of IN cord-022526-j9kg00qf 404 7 equipment equipment NN cord-022526-j9kg00qf 404 8 needed need VBN cord-022526-j9kg00qf 404 9 , , , cord-022526-j9kg00qf 404 10 skill skill NN cord-022526-j9kg00qf 404 11 involved involve VBN cord-022526-j9kg00qf 404 12 , , , cord-022526-j9kg00qf 404 13 and and CC cord-022526-j9kg00qf 404 14 the the DT cord-022526-j9kg00qf 404 15 limitation limitation NN cord-022526-j9kg00qf 404 16 as as IN cord-022526-j9kg00qf 404 17 a a DT cord-022526-j9kg00qf 404 18 diagnostic diagnostic JJ cord-022526-j9kg00qf 404 19 modality modality NN cord-022526-j9kg00qf 404 20 , , , cord-022526-j9kg00qf 404 21 rather rather RB cord-022526-j9kg00qf 404 22 than than IN cord-022526-j9kg00qf 404 23 a a DT cord-022526-j9kg00qf 404 24 treatment treatment NN cord-022526-j9kg00qf 404 25 . . . cord-022526-j9kg00qf 405 1 68 68 CD cord-022526-j9kg00qf 405 2 Clinical clinical JJ cord-022526-j9kg00qf 405 3 applications application NNS cord-022526-j9kg00qf 405 4 of of IN cord-022526-j9kg00qf 405 5 diagnostic diagnostic JJ cord-022526-j9kg00qf 405 6 laparoscopy laparoscopy NNS cord-022526-j9kg00qf 405 7 include include VBP cord-022526-j9kg00qf 405 8 rectal rectal JJ cord-022526-j9kg00qf 405 9 tears tear NNS cord-022526-j9kg00qf 405 10 , , , cord-022526-j9kg00qf 405 11 percutaneous percutaneous JJ cord-022526-j9kg00qf 405 12 abscess abscess NN cord-022526-j9kg00qf 405 13 drainage drainage NN cord-022526-j9kg00qf 405 14 , , , cord-022526-j9kg00qf 405 15 assessment assessment NN cord-022526-j9kg00qf 405 16 of of IN cord-022526-j9kg00qf 405 17 adhesions adhesion NNS cord-022526-j9kg00qf 405 18 , , , cord-022526-j9kg00qf 405 19 displacements displacement NNS cord-022526-j9kg00qf 405 20 , , , cord-022526-j9kg00qf 405 21 and and CC cord-022526-j9kg00qf 405 22 integrity integrity NN cord-022526-j9kg00qf 405 23 of of IN cord-022526-j9kg00qf 405 24 the the DT cord-022526-j9kg00qf 405 25 serosa serosa NNP cord-022526-j9kg00qf 405 26 of of IN cord-022526-j9kg00qf 405 27 various various JJ cord-022526-j9kg00qf 405 28 bowel bowel NN cord-022526-j9kg00qf 405 29 segments segment NNS cord-022526-j9kg00qf 405 30 , , , cord-022526-j9kg00qf 405 31 and and CC cord-022526-j9kg00qf 405 32 biopsy biopsy NN cord-022526-j9kg00qf 405 33 of of IN cord-022526-j9kg00qf 405 34 abdominal abdominal JJ cord-022526-j9kg00qf 405 35 masses masse NNS cord-022526-j9kg00qf 405 36 . . . cord-022526-j9kg00qf 406 1 67 67 CD cord-022526-j9kg00qf 406 2 Computed compute VBN cord-022526-j9kg00qf 406 3 tomography tomography NN cord-022526-j9kg00qf 406 4 scans scan NNS cord-022526-j9kg00qf 406 5 are be VBP cord-022526-j9kg00qf 406 6 available available JJ cord-022526-j9kg00qf 406 7 at at IN cord-022526-j9kg00qf 406 8 several several JJ cord-022526-j9kg00qf 406 9 universities university NNS cord-022526-j9kg00qf 406 10 across across IN cord-022526-j9kg00qf 406 11 the the DT cord-022526-j9kg00qf 406 12 country country NN cord-022526-j9kg00qf 406 13 . . . cord-022526-j9kg00qf 407 1 They -PRON- PRP cord-022526-j9kg00qf 407 2 have have VBP cord-022526-j9kg00qf 407 3 been be VBN cord-022526-j9kg00qf 407 4 used use VBN cord-022526-j9kg00qf 407 5 frequently frequently RB cord-022526-j9kg00qf 407 6 to to TO cord-022526-j9kg00qf 407 7 evaluate evaluate VB cord-022526-j9kg00qf 407 8 dental dental JJ cord-022526-j9kg00qf 407 9 disease disease NN cord-022526-j9kg00qf 407 10 and and CC cord-022526-j9kg00qf 407 11 may may MD cord-022526-j9kg00qf 407 12 be be VB cord-022526-j9kg00qf 407 13 useful useful JJ cord-022526-j9kg00qf 407 14 in in IN cord-022526-j9kg00qf 407 15 evaluating evaluate VBG cord-022526-j9kg00qf 407 16 tumors tumor NNS cord-022526-j9kg00qf 407 17 and and CC cord-022526-j9kg00qf 407 18 masses masse NNS cord-022526-j9kg00qf 407 19 of of IN cord-022526-j9kg00qf 407 20 the the DT cord-022526-j9kg00qf 407 21 head head NN cord-022526-j9kg00qf 407 22 , , , cord-022526-j9kg00qf 407 23 larynx larynx NN cord-022526-j9kg00qf 407 24 , , , cord-022526-j9kg00qf 407 25 pharynx pharynx NN cord-022526-j9kg00qf 407 26 , , , cord-022526-j9kg00qf 407 27 and and CC cord-022526-j9kg00qf 407 28 proximal proximal JJ cord-022526-j9kg00qf 407 29 esophagus esophagus NN cord-022526-j9kg00qf 407 30 . . . cord-022526-j9kg00qf 408 1 69 69 CD cord-022526-j9kg00qf 408 2 Computed compute VBN cord-022526-j9kg00qf 408 3 tomography tomography NN cord-022526-j9kg00qf 408 4 also also RB cord-022526-j9kg00qf 408 5 has have VBZ cord-022526-j9kg00qf 408 6 promise promise NN cord-022526-j9kg00qf 408 7 for for IN cord-022526-j9kg00qf 408 8 evaluating evaluate VBG cord-022526-j9kg00qf 408 9 abdominal abdominal JJ cord-022526-j9kg00qf 408 10 disorders disorder NNS cord-022526-j9kg00qf 408 11 in in IN cord-022526-j9kg00qf 408 12 foals foal NNS cord-022526-j9kg00qf 408 13 . . . cord-022526-j9kg00qf 409 1 Most Most JJS cord-022526-j9kg00qf 409 2 equipment equipment NN cord-022526-j9kg00qf 409 3 can can MD cord-022526-j9kg00qf 409 4 accommodate accommodate VB cord-022526-j9kg00qf 409 5 up up RP cord-022526-j9kg00qf 409 6 to to TO cord-022526-j9kg00qf 409 7 400 400 CD cord-022526-j9kg00qf 409 8 lb lb CD cord-022526-j9kg00qf 409 9 . . . cord-022526-j9kg00qf 410 1 Restrictions restriction NNS cord-022526-j9kg00qf 410 2 to to IN cord-022526-j9kg00qf 410 3 computed compute VBN cord-022526-j9kg00qf 410 4 tomography tomography NN cord-022526-j9kg00qf 410 5 as as IN cord-022526-j9kg00qf 410 6 a a DT cord-022526-j9kg00qf 410 7 diagnostic diagnostic JJ cord-022526-j9kg00qf 410 8 aid aid NN cord-022526-j9kg00qf 410 9 include include VBP cord-022526-j9kg00qf 410 10 expense expense NN cord-022526-j9kg00qf 410 11 , , , cord-022526-j9kg00qf 410 12 availability availability NN cord-022526-j9kg00qf 410 13 , , , cord-022526-j9kg00qf 410 14 expertise expertise NN cord-022526-j9kg00qf 410 15 , , , cord-022526-j9kg00qf 410 16 and and CC cord-022526-j9kg00qf 410 17 weight weight NN cord-022526-j9kg00qf 410 18 and and CC cord-022526-j9kg00qf 410 19 size size NN cord-022526-j9kg00qf 410 20 limitation limitation NN cord-022526-j9kg00qf 410 21 . . . cord-022526-j9kg00qf 411 1 12 12 CD cord-022526-j9kg00qf 411 2 permeability permeability NN cord-022526-j9kg00qf 411 3 increases increase NNS cord-022526-j9kg00qf 411 4 , , , cord-022526-j9kg00qf 411 5 cells cell NNS cord-022526-j9kg00qf 411 6 are be VBP cord-022526-j9kg00qf 411 7 recruited recruit VBN cord-022526-j9kg00qf 411 8 rapidly rapidly RB cord-022526-j9kg00qf 411 9 into into IN cord-022526-j9kg00qf 411 10 the the DT cord-022526-j9kg00qf 411 11 tissue tissue NN cord-022526-j9kg00qf 411 12 , , , cord-022526-j9kg00qf 411 13 plasma plasma NN cord-022526-j9kg00qf 411 14 protein protein NN cord-022526-j9kg00qf 411 15 cascades cascade NNS cord-022526-j9kg00qf 411 16 are be VBP cord-022526-j9kg00qf 411 17 activated activate VBN cord-022526-j9kg00qf 411 18 , , , cord-022526-j9kg00qf 411 19 and and CC cord-022526-j9kg00qf 411 20 a a DT cord-022526-j9kg00qf 411 21 myriad myriad NN cord-022526-j9kg00qf 411 22 of of IN cord-022526-j9kg00qf 411 23 soluble soluble JJ cord-022526-j9kg00qf 411 24 products product NNS cord-022526-j9kg00qf 411 25 are be VBP cord-022526-j9kg00qf 411 26 released release VBN cord-022526-j9kg00qf 411 27 that that WDT cord-022526-j9kg00qf 411 28 coordinate coordinate VBP cord-022526-j9kg00qf 411 29 the the DT cord-022526-j9kg00qf 411 30 response response NN cord-022526-j9kg00qf 411 31 , , , cord-022526-j9kg00qf 411 32 trigger trigger NN cord-022526-j9kg00qf 411 33 innate innate JJ cord-022526-j9kg00qf 411 34 and and CC cord-022526-j9kg00qf 411 35 adaptive adaptive JJ cord-022526-j9kg00qf 411 36 immunity immunity NN cord-022526-j9kg00qf 411 37 , , , cord-022526-j9kg00qf 411 38 and and CC cord-022526-j9kg00qf 411 39 mobilize mobilize VB cord-022526-j9kg00qf 411 40 reparative reparative JJ cord-022526-j9kg00qf 411 41 elements element NNS cord-022526-j9kg00qf 411 42 . . . cord-022526-j9kg00qf 412 1 Although although IN cord-022526-j9kg00qf 412 2 the the DT cord-022526-j9kg00qf 412 3 cellular cellular JJ cord-022526-j9kg00qf 412 4 and and CC cord-022526-j9kg00qf 412 5 vascular vascular JJ cord-022526-j9kg00qf 412 6 response response NN cord-022526-j9kg00qf 412 7 and and CC cord-022526-j9kg00qf 412 8 the the DT cord-022526-j9kg00qf 412 9 secreted secrete VBN cord-022526-j9kg00qf 412 10 mediators mediator NNS cord-022526-j9kg00qf 412 11 of of IN cord-022526-j9kg00qf 412 12 inflammation inflammation NN cord-022526-j9kg00qf 412 13 are be VBP cord-022526-j9kg00qf 412 14 important important JJ cord-022526-j9kg00qf 412 15 for for IN cord-022526-j9kg00qf 412 16 killing kill VBG cord-022526-j9kg00qf 412 17 pathogens pathogen NNS cord-022526-j9kg00qf 412 18 and and CC cord-022526-j9kg00qf 412 19 limiting limit VBG cord-022526-j9kg00qf 412 20 invasion invasion NN cord-022526-j9kg00qf 412 21 of of IN cord-022526-j9kg00qf 412 22 injured injured JJ cord-022526-j9kg00qf 412 23 tissues tissue NNS cord-022526-j9kg00qf 412 24 by by IN cord-022526-j9kg00qf 412 25 commensal commensal JJ cord-022526-j9kg00qf 412 26 organisms organism NNS cord-022526-j9kg00qf 412 27 , , , cord-022526-j9kg00qf 412 28 they -PRON- PRP cord-022526-j9kg00qf 412 29 can can MD cord-022526-j9kg00qf 412 30 be be VB cord-022526-j9kg00qf 412 31 damaging damaging JJ cord-022526-j9kg00qf 412 32 to to IN cord-022526-j9kg00qf 412 33 host host NN cord-022526-j9kg00qf 412 34 cells cell NNS cord-022526-j9kg00qf 412 35 and and CC cord-022526-j9kg00qf 412 36 proteins protein NNS cord-022526-j9kg00qf 412 37 if if IN cord-022526-j9kg00qf 412 38 not not RB cord-022526-j9kg00qf 412 39 tightly tightly RB cord-022526-j9kg00qf 412 40 regulated regulate VBN cord-022526-j9kg00qf 412 41 . . . cord-022526-j9kg00qf 413 1 Thus thus RB cord-022526-j9kg00qf 413 2 if if IN cord-022526-j9kg00qf 413 3 the the DT cord-022526-j9kg00qf 413 4 inciting incite VBG cord-022526-j9kg00qf 413 5 stimulus stimulus NN cord-022526-j9kg00qf 413 6 is be VBZ cord-022526-j9kg00qf 413 7 not not RB cord-022526-j9kg00qf 413 8 eliminated eliminate VBN cord-022526-j9kg00qf 413 9 quickly quickly RB cord-022526-j9kg00qf 413 10 , , , cord-022526-j9kg00qf 413 11 the the DT cord-022526-j9kg00qf 413 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 413 13 response response NN cord-022526-j9kg00qf 413 14 itself -PRON- PRP cord-022526-j9kg00qf 413 15 causes cause VBZ cord-022526-j9kg00qf 413 16 significant significant JJ cord-022526-j9kg00qf 413 17 tissue tissue NN cord-022526-j9kg00qf 413 18 injury injury NN cord-022526-j9kg00qf 413 19 . . . cord-022526-j9kg00qf 414 1 The the DT cord-022526-j9kg00qf 414 2 mechanism mechanism NN cord-022526-j9kg00qf 414 3 regulating regulate VBG cord-022526-j9kg00qf 414 4 inflammation inflammation NN cord-022526-j9kg00qf 414 5 has have VBZ cord-022526-j9kg00qf 414 6 been be VBN cord-022526-j9kg00qf 414 7 the the DT cord-022526-j9kg00qf 414 8 focus focus NN cord-022526-j9kg00qf 414 9 of of IN cord-022526-j9kg00qf 414 10 much much JJ cord-022526-j9kg00qf 414 11 research research NN cord-022526-j9kg00qf 414 12 to to TO cord-022526-j9kg00qf 414 13 identify identify VB cord-022526-j9kg00qf 414 14 therapeutic therapeutic JJ cord-022526-j9kg00qf 414 15 targets target NNS cord-022526-j9kg00qf 414 16 to to TO cord-022526-j9kg00qf 414 17 modulate modulate VB cord-022526-j9kg00qf 414 18 the the DT cord-022526-j9kg00qf 414 19 damage damage NN cord-022526-j9kg00qf 414 20 to to TO cord-022526-j9kg00qf 414 21 host host VB cord-022526-j9kg00qf 414 22 tissues tissue NNS cord-022526-j9kg00qf 414 23 during during IN cord-022526-j9kg00qf 414 24 many many JJ cord-022526-j9kg00qf 414 25 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 414 26 diseases disease NNS cord-022526-j9kg00qf 414 27 . . . cord-022526-j9kg00qf 415 1 Recent recent JJ cord-022526-j9kg00qf 415 2 work work NN cord-022526-j9kg00qf 415 3 has have VBZ cord-022526-j9kg00qf 415 4 provided provide VBN cord-022526-j9kg00qf 415 5 some some DT cord-022526-j9kg00qf 415 6 of of IN cord-022526-j9kg00qf 415 7 the the DT cord-022526-j9kg00qf 415 8 molecular molecular JJ cord-022526-j9kg00qf 415 9 and and CC cord-022526-j9kg00qf 415 10 cellular cellular JJ cord-022526-j9kg00qf 415 11 details detail NNS cord-022526-j9kg00qf 415 12 of of IN cord-022526-j9kg00qf 415 13 this this DT cord-022526-j9kg00qf 415 14 complex complex JJ cord-022526-j9kg00qf 415 15 physiology physiology NN cord-022526-j9kg00qf 415 16 and and CC cord-022526-j9kg00qf 415 17 has have VBZ cord-022526-j9kg00qf 415 18 led lead VBN cord-022526-j9kg00qf 415 19 to to IN cord-022526-j9kg00qf 415 20 novel novel JJ cord-022526-j9kg00qf 415 21 therapeutic therapeutic JJ cord-022526-j9kg00qf 415 22 strategies strategy NNS cord-022526-j9kg00qf 415 23 for for IN cord-022526-j9kg00qf 415 24 treating treat VBG cord-022526-j9kg00qf 415 25 inflammation inflammation NN cord-022526-j9kg00qf 415 26 . . . cord-022526-j9kg00qf 416 1 The the DT cord-022526-j9kg00qf 416 2 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 416 3 epithelium epithelium NN cord-022526-j9kg00qf 416 4 interfaces interface NNS cord-022526-j9kg00qf 416 5 with with IN cord-022526-j9kg00qf 416 6 a a DT cord-022526-j9kg00qf 416 7 luminal luminal JJ cord-022526-j9kg00qf 416 8 environment environment NN cord-022526-j9kg00qf 416 9 inhabited inhabit VBN cord-022526-j9kg00qf 416 10 by by IN cord-022526-j9kg00qf 416 11 potentially potentially RB cord-022526-j9kg00qf 416 12 hostile hostile JJ cord-022526-j9kg00qf 416 13 microbial microbial JJ cord-022526-j9kg00qf 416 14 organisms organism NNS cord-022526-j9kg00qf 416 15 . . . cord-022526-j9kg00qf 417 1 The the DT cord-022526-j9kg00qf 417 2 epithelium epithelium NN cord-022526-j9kg00qf 417 3 presents present VBZ cord-022526-j9kg00qf 417 4 a a DT cord-022526-j9kg00qf 417 5 physical physical JJ cord-022526-j9kg00qf 417 6 barrier barrier NN cord-022526-j9kg00qf 417 7 to to IN cord-022526-j9kg00qf 417 8 invasion invasion NN cord-022526-j9kg00qf 417 9 by by IN cord-022526-j9kg00qf 417 10 the the DT cord-022526-j9kg00qf 417 11 flora flora NNS cord-022526-j9kg00qf 417 12 of of IN cord-022526-j9kg00qf 417 13 the the DT cord-022526-j9kg00qf 417 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 417 15 tract tract NN cord-022526-j9kg00qf 417 16 , , , cord-022526-j9kg00qf 417 17 consisting consist VBG cord-022526-j9kg00qf 417 18 of of IN cord-022526-j9kg00qf 417 19 the the DT cord-022526-j9kg00qf 417 20 apical apical JJ cord-022526-j9kg00qf 417 21 cellular cellular JJ cord-022526-j9kg00qf 417 22 membrane membrane NN cord-022526-j9kg00qf 417 23 , , , cord-022526-j9kg00qf 417 24 intercellular intercellular JJ cord-022526-j9kg00qf 417 25 tight tight JJ cord-022526-j9kg00qf 417 26 junctions junction NNS cord-022526-j9kg00qf 417 27 the the DT cord-022526-j9kg00qf 417 28 permeability permeability NN cord-022526-j9kg00qf 417 29 of of IN cord-022526-j9kg00qf 417 30 which which WDT cord-022526-j9kg00qf 417 31 is be VBZ cord-022526-j9kg00qf 417 32 highly highly RB cord-022526-j9kg00qf 417 33 regulated regulate VBN cord-022526-j9kg00qf 417 34 , , , cord-022526-j9kg00qf 417 35 and and CC cord-022526-j9kg00qf 417 36 a a DT cord-022526-j9kg00qf 417 37 secreted secrete VBN cord-022526-j9kg00qf 417 38 layer layer NN cord-022526-j9kg00qf 417 39 of of IN cord-022526-j9kg00qf 417 40 mucus mucus NN cord-022526-j9kg00qf 417 41 . . . cord-022526-j9kg00qf 418 1 Breaching breach VBG cord-022526-j9kg00qf 418 2 of of IN cord-022526-j9kg00qf 418 3 the the DT cord-022526-j9kg00qf 418 4 mucosal mucosal JJ cord-022526-j9kg00qf 418 5 barrier barrier NN cord-022526-j9kg00qf 418 6 by by IN cord-022526-j9kg00qf 418 7 invading invade VBG cord-022526-j9kg00qf 418 8 pathogens pathogen NNS cord-022526-j9kg00qf 418 9 generates generate VBZ cord-022526-j9kg00qf 418 10 potent potent JJ cord-022526-j9kg00qf 418 11 soluble soluble JJ cord-022526-j9kg00qf 418 12 and and CC cord-022526-j9kg00qf 418 13 neural neural JJ cord-022526-j9kg00qf 418 14 signals signal NNS cord-022526-j9kg00qf 418 15 that that WDT cord-022526-j9kg00qf 418 16 initiate initiate VBP cord-022526-j9kg00qf 418 17 an an DT cord-022526-j9kg00qf 418 18 inflammatory inflammatory JJ cord-022526-j9kg00qf 418 19 response response NN cord-022526-j9kg00qf 418 20 . . . cord-022526-j9kg00qf 419 1 1 1 LS cord-022526-j9kg00qf 420 1 Conceptually conceptually RB cord-022526-j9kg00qf 420 2 , , , cord-022526-j9kg00qf 420 3 the the DT cord-022526-j9kg00qf 420 4 epithelium epithelium NN cord-022526-j9kg00qf 420 5 can can MD cord-022526-j9kg00qf 420 6 be be VB cord-022526-j9kg00qf 420 7 thought think VBN cord-022526-j9kg00qf 420 8 of of IN cord-022526-j9kg00qf 420 9 as as IN cord-022526-j9kg00qf 420 10 a a DT cord-022526-j9kg00qf 420 11 sensory sensory JJ cord-022526-j9kg00qf 420 12 organ organ NN cord-022526-j9kg00qf 420 13 detecting detect VBG cord-022526-j9kg00qf 420 14 pathogen pathogen NN cord-022526-j9kg00qf 420 15 invasion invasion NN cord-022526-j9kg00qf 420 16 to to TO cord-022526-j9kg00qf 420 17 trigger trigger VB cord-022526-j9kg00qf 420 18 an an DT cord-022526-j9kg00qf 420 19 appropriate appropriate JJ cord-022526-j9kg00qf 420 20 host host NN cord-022526-j9kg00qf 420 21 defense defense NN cord-022526-j9kg00qf 420 22 and and CC cord-022526-j9kg00qf 420 23 reparative reparative JJ cord-022526-j9kg00qf 420 24 response response NN cord-022526-j9kg00qf 420 25 . . . cord-022526-j9kg00qf 421 1 Noninfectious noninfectious JJ cord-022526-j9kg00qf 421 2 mucosal mucosal JJ cord-022526-j9kg00qf 421 3 injury injury NN cord-022526-j9kg00qf 421 4 or or CC cord-022526-j9kg00qf 421 5 invasion invasion NN cord-022526-j9kg00qf 421 6 of of IN cord-022526-j9kg00qf 421 7 epithelial epithelial JJ cord-022526-j9kg00qf 421 8 cells cell NNS cord-022526-j9kg00qf 421 9 by by IN cord-022526-j9kg00qf 421 10 pathogenic pathogenic JJ cord-022526-j9kg00qf 421 11 organisms organism NNS cord-022526-j9kg00qf 421 12 such such JJ cord-022526-j9kg00qf 421 13 as as IN cord-022526-j9kg00qf 421 14 Salmonella Salmonella NNP cord-022526-j9kg00qf 421 15 activates activate VBZ cord-022526-j9kg00qf 421 16 synthesis synthesis NN cord-022526-j9kg00qf 421 17 of of IN cord-022526-j9kg00qf 421 18 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 421 19 chemokines chemokine NNS cord-022526-j9kg00qf 421 20 ( ( -LRB- cord-022526-j9kg00qf 421 21 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 421 22 ) ) -RRB- cord-022526-j9kg00qf 421 23 by by IN cord-022526-j9kg00qf 421 24 epithelial epithelial JJ cord-022526-j9kg00qf 421 25 cells cell NNS cord-022526-j9kg00qf 421 26 and and CC cord-022526-j9kg00qf 421 27 triggers trigger VBZ cord-022526-j9kg00qf 421 28 a a DT cord-022526-j9kg00qf 421 29 robust robust JJ cord-022526-j9kg00qf 421 30 influx influx NN cord-022526-j9kg00qf 421 31 of of IN cord-022526-j9kg00qf 421 32 neutrophils neutrophil NNS cord-022526-j9kg00qf 421 33 into into IN cord-022526-j9kg00qf 421 34 the the DT cord-022526-j9kg00qf 421 35 tissue tissue NN cord-022526-j9kg00qf 421 36 within within IN cord-022526-j9kg00qf 421 37 hours hour NNS cord-022526-j9kg00qf 421 38 of of IN cord-022526-j9kg00qf 421 39 the the DT cord-022526-j9kg00qf 421 40 damage damage NN cord-022526-j9kg00qf 421 41 . . . cord-022526-j9kg00qf 422 1 1 1 CD cord-022526-j9kg00qf 422 2 Of of IN cord-022526-j9kg00qf 422 3 the the DT cord-022526-j9kg00qf 422 4 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 422 5 produced produce VBN cord-022526-j9kg00qf 422 6 by by IN cord-022526-j9kg00qf 422 7 epithelium epithelium NN cord-022526-j9kg00qf 422 8 , , , cord-022526-j9kg00qf 422 9 interleukin-8 interleukin-8 NNP cord-022526-j9kg00qf 422 10 ( ( -LRB- cord-022526-j9kg00qf 422 11 IL-8 il-8 NN cord-022526-j9kg00qf 422 12 ) ) -RRB- cord-022526-j9kg00qf 422 13 has have VBZ cord-022526-j9kg00qf 422 14 a a DT cord-022526-j9kg00qf 422 15 particularly particularly RB cord-022526-j9kg00qf 422 16 important important JJ cord-022526-j9kg00qf 422 17 role role NN cord-022526-j9kg00qf 422 18 in in IN cord-022526-j9kg00qf 422 19 initiating initiate VBG cord-022526-j9kg00qf 422 20 inflammation inflammation NN cord-022526-j9kg00qf 422 21 by by IN cord-022526-j9kg00qf 422 22 recruiting recruit VBG cord-022526-j9kg00qf 422 23 neutrophils neutrophil NNS cord-022526-j9kg00qf 422 24 from from IN cord-022526-j9kg00qf 422 25 blood blood NN cord-022526-j9kg00qf 422 26 [ [ -LRB- cord-022526-j9kg00qf 422 27 2 2 CD cord-022526-j9kg00qf 422 28 ] ] -RRB- cord-022526-j9kg00qf 422 29 [ [ -LRB- cord-022526-j9kg00qf 422 30 3 3 CD cord-022526-j9kg00qf 422 31 ] ] -RRB- cord-022526-j9kg00qf 422 32 [ [ -LRB- cord-022526-j9kg00qf 422 33 4 4 CD cord-022526-j9kg00qf 422 34 ] ] -RRB- cord-022526-j9kg00qf 422 35 and and CC cord-022526-j9kg00qf 422 36 regulating regulate VBG cord-022526-j9kg00qf 422 37 neutrophil neutrophil NN cord-022526-j9kg00qf 422 38 migration migration NN cord-022526-j9kg00qf 422 39 through through IN cord-022526-j9kg00qf 422 40 tissue tissue NN cord-022526-j9kg00qf 422 41 matrix matrix NN cord-022526-j9kg00qf 422 42 adjacent adjacent JJ cord-022526-j9kg00qf 422 43 to to IN cord-022526-j9kg00qf 422 44 epithelium epithelium NN cord-022526-j9kg00qf 422 45 . . . cord-022526-j9kg00qf 423 1 5 5 CD cord-022526-j9kg00qf 423 2 , , , cord-022526-j9kg00qf 423 3 6 6 CD cord-022526-j9kg00qf 423 4 Bacteriaderived Bacteriaderived NNP cord-022526-j9kg00qf 423 5 formylated formylated JJ cord-022526-j9kg00qf 423 6 chemotactic chemotactic JJ cord-022526-j9kg00qf 423 7 peptides peptide NNS cord-022526-j9kg00qf 423 8 also also RB cord-022526-j9kg00qf 423 9 act act VBP cord-022526-j9kg00qf 423 10 as as IN cord-022526-j9kg00qf 423 11 potent potent JJ cord-022526-j9kg00qf 423 12 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 423 13 that that WDT cord-022526-j9kg00qf 423 14 are be VBP cord-022526-j9kg00qf 423 15 fully fully RB cord-022526-j9kg00qf 423 16 capable capable JJ cord-022526-j9kg00qf 423 17 of of IN cord-022526-j9kg00qf 423 18 stimulating stimulate VBG cord-022526-j9kg00qf 423 19 a a DT cord-022526-j9kg00qf 423 20 robust robust JJ cord-022526-j9kg00qf 423 21 inflammatory inflammatory JJ cord-022526-j9kg00qf 423 22 response response NN cord-022526-j9kg00qf 423 23 in in IN cord-022526-j9kg00qf 423 24 the the DT cord-022526-j9kg00qf 423 25 intestine intestine NN cord-022526-j9kg00qf 423 26 if if IN cord-022526-j9kg00qf 423 27 the the DT cord-022526-j9kg00qf 423 28 epithelial epithelial JJ cord-022526-j9kg00qf 423 29 barrier barrier NN cord-022526-j9kg00qf 423 30 permits permit VBZ cord-022526-j9kg00qf 423 31 the the DT cord-022526-j9kg00qf 423 32 diffusion diffusion NN cord-022526-j9kg00qf 423 33 of of IN cord-022526-j9kg00qf 423 34 the the DT cord-022526-j9kg00qf 423 35 peptides peptide NNS cord-022526-j9kg00qf 423 36 across across IN cord-022526-j9kg00qf 423 37 the the DT cord-022526-j9kg00qf 423 38 mucosa mucosa NN cord-022526-j9kg00qf 423 39 . . . cord-022526-j9kg00qf 424 1 Epithelial epithelial JJ cord-022526-j9kg00qf 424 2 cells cell NNS cord-022526-j9kg00qf 424 3 activated activate VBN cord-022526-j9kg00qf 424 4 during during IN cord-022526-j9kg00qf 424 5 infection infection NN cord-022526-j9kg00qf 424 6 produce produce VBP cord-022526-j9kg00qf 424 7 cytokines cytokine NNS cord-022526-j9kg00qf 424 8 such such JJ cord-022526-j9kg00qf 424 9 as as IN cord-022526-j9kg00qf 424 10 tumor tumor NN cord-022526-j9kg00qf 424 11 necrosis necrosis NN cord-022526-j9kg00qf 424 12 factor factor NN cord-022526-j9kg00qf 424 13 α α NNP cord-022526-j9kg00qf 424 14 ( ( -LRB- cord-022526-j9kg00qf 424 15 TNF TNF NNP cord-022526-j9kg00qf 424 16 - - HYPH cord-022526-j9kg00qf 424 17 α α NNP cord-022526-j9kg00qf 424 18 ) ) -RRB- cord-022526-j9kg00qf 424 19 , , , cord-022526-j9kg00qf 424 20 arachidonic arachidonic JJ cord-022526-j9kg00qf 424 21 acid acid NN cord-022526-j9kg00qf 424 22 metabolites metabolite NNS cord-022526-j9kg00qf 424 23 , , , cord-022526-j9kg00qf 424 24 and and CC cord-022526-j9kg00qf 424 25 other other JJ cord-022526-j9kg00qf 424 26 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 424 27 mediators mediator NNS cord-022526-j9kg00qf 424 28 that that WDT cord-022526-j9kg00qf 424 29 activate activate VBP cord-022526-j9kg00qf 424 30 recruited recruit VBN cord-022526-j9kg00qf 424 31 leukocytes leukocyte NNS cord-022526-j9kg00qf 424 32 . . . cord-022526-j9kg00qf 425 1 7 7 CD cord-022526-j9kg00qf 425 2 Bacterial bacterial JJ cord-022526-j9kg00qf 425 3 products product NNS cord-022526-j9kg00qf 425 4 , , , cord-022526-j9kg00qf 425 5 particularly particularly RB cord-022526-j9kg00qf 425 6 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 425 7 and and CC cord-022526-j9kg00qf 425 8 other other JJ cord-022526-j9kg00qf 425 9 cell cell NN cord-022526-j9kg00qf 425 10 wall wall NN cord-022526-j9kg00qf 425 11 components component NNS cord-022526-j9kg00qf 425 12 , , , cord-022526-j9kg00qf 425 13 are be VBP cord-022526-j9kg00qf 425 14 potent potent JJ cord-022526-j9kg00qf 425 15 activators activator NNS cord-022526-j9kg00qf 425 16 of of IN cord-022526-j9kg00qf 425 17 leukocytes leukocyte NNS cord-022526-j9kg00qf 425 18 recruited recruit VBN cord-022526-j9kg00qf 425 19 into into IN cord-022526-j9kg00qf 425 20 the the DT cord-022526-j9kg00qf 425 21 tissue tissue NN cord-022526-j9kg00qf 425 22 . . . cord-022526-j9kg00qf 426 1 Once once IN cord-022526-j9kg00qf 426 2 the the DT cord-022526-j9kg00qf 426 3 inflammatory inflammatory JJ cord-022526-j9kg00qf 426 4 response response NN cord-022526-j9kg00qf 426 5 has have VBZ cord-022526-j9kg00qf 426 6 been be VBN cord-022526-j9kg00qf 426 7 initiated initiate VBN cord-022526-j9kg00qf 426 8 , , , cord-022526-j9kg00qf 426 9 TNF TNF NNP cord-022526-j9kg00qf 426 10 - - HYPH cord-022526-j9kg00qf 426 11 α α NNP cord-022526-j9kg00qf 426 12 , , , cord-022526-j9kg00qf 426 13 IL-1β IL-1β NNP cord-022526-j9kg00qf 426 14 , , , cord-022526-j9kg00qf 426 15 and and CC cord-022526-j9kg00qf 426 16 other other JJ cord-022526-j9kg00qf 426 17 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 426 18 products product NNS cord-022526-j9kg00qf 426 19 of of IN cord-022526-j9kg00qf 426 20 neutrophils neutrophil NNS cord-022526-j9kg00qf 426 21 , , , cord-022526-j9kg00qf 426 22 monocytes monocyte NNS cord-022526-j9kg00qf 426 23 , , , cord-022526-j9kg00qf 426 24 mast mast NN cord-022526-j9kg00qf 426 25 cells cell NNS cord-022526-j9kg00qf 426 26 , , , cord-022526-j9kg00qf 426 27 and and CC cord-022526-j9kg00qf 426 28 epithelial epithelial JJ cord-022526-j9kg00qf 426 29 cells cell NNS cord-022526-j9kg00qf 426 30 amplify amplify VBP cord-022526-j9kg00qf 426 31 the the DT cord-022526-j9kg00qf 426 32 inflammatory inflammatory JJ cord-022526-j9kg00qf 426 33 response response NN cord-022526-j9kg00qf 426 34 . . . cord-022526-j9kg00qf 427 1 The the DT cord-022526-j9kg00qf 427 2 enteric enteric JJ cord-022526-j9kg00qf 427 3 nervous nervous JJ cord-022526-j9kg00qf 427 4 system system NN cord-022526-j9kg00qf 427 5 has have VBZ cord-022526-j9kg00qf 427 6 a a DT cord-022526-j9kg00qf 427 7 key key JJ cord-022526-j9kg00qf 427 8 role role NN cord-022526-j9kg00qf 427 9 in in IN cord-022526-j9kg00qf 427 10 sensing sensing NN cord-022526-j9kg00qf 427 11 and and CC cord-022526-j9kg00qf 427 12 regulating regulate VBG cord-022526-j9kg00qf 427 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 427 14 responses response NNS cord-022526-j9kg00qf 427 15 in in IN cord-022526-j9kg00qf 427 16 the the DT cord-022526-j9kg00qf 427 17 intestine intestine NN cord-022526-j9kg00qf 427 18 . . . cord-022526-j9kg00qf 428 1 For for IN cord-022526-j9kg00qf 428 2 example example NN cord-022526-j9kg00qf 428 3 , , , cord-022526-j9kg00qf 428 4 Clostridium clostridium NN cord-022526-j9kg00qf 428 5 difficile difficile NN cord-022526-j9kg00qf 428 6 toxin toxin NN cord-022526-j9kg00qf 428 7 A a NN cord-022526-j9kg00qf 428 8 activates activate VBZ cord-022526-j9kg00qf 428 9 a a DT cord-022526-j9kg00qf 428 10 neural neural JJ cord-022526-j9kg00qf 428 11 pathway pathway NN cord-022526-j9kg00qf 428 12 that that WDT cord-022526-j9kg00qf 428 13 triggers trigger VBZ cord-022526-j9kg00qf 428 14 mast mast JJ cord-022526-j9kg00qf 428 15 cell cell NN cord-022526-j9kg00qf 428 16 degranulation degranulation NN cord-022526-j9kg00qf 428 17 and and CC cord-022526-j9kg00qf 428 18 neutrophil neutrophil NN cord-022526-j9kg00qf 428 19 influx influx NN cord-022526-j9kg00qf 428 20 into into IN cord-022526-j9kg00qf 428 21 the the DT cord-022526-j9kg00qf 428 22 tissue tissue NN cord-022526-j9kg00qf 428 23 . . . cord-022526-j9kg00qf 429 1 8 8 CD cord-022526-j9kg00qf 429 2 , , , cord-022526-j9kg00qf 429 3 9 9 CD cord-022526-j9kg00qf 429 4 Blockade blockade NN cord-022526-j9kg00qf 429 5 of of IN cord-022526-j9kg00qf 429 6 this this DT cord-022526-j9kg00qf 429 7 neural neural JJ cord-022526-j9kg00qf 429 8 pathway pathway NN cord-022526-j9kg00qf 429 9 is be VBZ cord-022526-j9kg00qf 429 10 sufficient sufficient JJ cord-022526-j9kg00qf 429 11 to to TO cord-022526-j9kg00qf 429 12 abolish abolish VB cord-022526-j9kg00qf 429 13 the the DT cord-022526-j9kg00qf 429 14 profound profound JJ cord-022526-j9kg00qf 429 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 429 16 response response NN cord-022526-j9kg00qf 429 17 induced induce VBN cord-022526-j9kg00qf 429 18 by by IN cord-022526-j9kg00qf 429 19 toxin toxin NN cord-022526-j9kg00qf 429 20 A a NN cord-022526-j9kg00qf 429 21 and and CC cord-022526-j9kg00qf 429 22 many many JJ cord-022526-j9kg00qf 429 23 of of IN cord-022526-j9kg00qf 429 24 the the DT cord-022526-j9kg00qf 429 25 effects effect NNS cord-022526-j9kg00qf 429 26 of of IN cord-022526-j9kg00qf 429 27 toxin toxin NN cord-022526-j9kg00qf 429 28 A a NN cord-022526-j9kg00qf 429 29 on on IN cord-022526-j9kg00qf 429 30 enterocyte enterocyte JJ cord-022526-j9kg00qf 429 31 secretion secretion NN cord-022526-j9kg00qf 429 32 . . . cord-022526-j9kg00qf 430 1 Other other JJ cord-022526-j9kg00qf 430 2 pathogens pathogen NNS cord-022526-j9kg00qf 430 3 and and CC cord-022526-j9kg00qf 430 4 immune immune NN cord-022526-j9kg00qf 430 5 - - HYPH cord-022526-j9kg00qf 430 6 mediated mediate VBN cord-022526-j9kg00qf 430 7 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 430 8 reactions reaction NNS cord-022526-j9kg00qf 430 9 similarly similarly RB cord-022526-j9kg00qf 430 10 stimulate stimulate VBP cord-022526-j9kg00qf 430 11 inflammation inflammation NN cord-022526-j9kg00qf 430 12 by by IN cord-022526-j9kg00qf 430 13 mechanisms mechanism NNS cord-022526-j9kg00qf 430 14 that that WDT cord-022526-j9kg00qf 430 15 involve involve VBP cord-022526-j9kg00qf 430 16 the the DT cord-022526-j9kg00qf 430 17 enteric enteric JJ cord-022526-j9kg00qf 430 18 nervous nervous JJ cord-022526-j9kg00qf 430 19 system system NN cord-022526-j9kg00qf 430 20 . . . cord-022526-j9kg00qf 431 1 Thus thus RB cord-022526-j9kg00qf 431 2 the the DT cord-022526-j9kg00qf 431 3 epithelium epithelium NN cord-022526-j9kg00qf 431 4 interacts interact VBZ cord-022526-j9kg00qf 431 5 in in IN cord-022526-j9kg00qf 431 6 a a DT cord-022526-j9kg00qf 431 7 highly highly RB cord-022526-j9kg00qf 431 8 complex complex JJ cord-022526-j9kg00qf 431 9 manner manner NN cord-022526-j9kg00qf 431 10 with with IN cord-022526-j9kg00qf 431 11 the the DT cord-022526-j9kg00qf 431 12 intestinal intestinal JJ cord-022526-j9kg00qf 431 13 milieu milieu NN cord-022526-j9kg00qf 431 14 , , , cord-022526-j9kg00qf 431 15 the the DT cord-022526-j9kg00qf 431 16 enteric enteric JJ cord-022526-j9kg00qf 431 17 nervous nervous JJ cord-022526-j9kg00qf 431 18 system system NN cord-022526-j9kg00qf 431 19 , , , cord-022526-j9kg00qf 431 20 and and CC cord-022526-j9kg00qf 431 21 inflammatory inflammatory JJ cord-022526-j9kg00qf 431 22 cells cell NNS cord-022526-j9kg00qf 431 23 to to TO cord-022526-j9kg00qf 431 24 regulate regulate VB cord-022526-j9kg00qf 431 25 the the DT cord-022526-j9kg00qf 431 26 tissue tissue NN cord-022526-j9kg00qf 431 27 response response NN cord-022526-j9kg00qf 431 28 to to IN cord-022526-j9kg00qf 431 29 injury injury NN cord-022526-j9kg00qf 431 30 and and CC cord-022526-j9kg00qf 431 31 infection infection NN cord-022526-j9kg00qf 431 32 . . . cord-022526-j9kg00qf 432 1 Resident resident JJ cord-022526-j9kg00qf 432 2 macrophages macrophage NNS cord-022526-j9kg00qf 432 3 located locate VBN cord-022526-j9kg00qf 432 4 in in IN cord-022526-j9kg00qf 432 5 the the DT cord-022526-j9kg00qf 432 6 lamina lamina JJ cord-022526-j9kg00qf 432 7 propria propria NNP cord-022526-j9kg00qf 432 8 , , , cord-022526-j9kg00qf 432 9 submucosa submucosa NNP cord-022526-j9kg00qf 432 10 , , , cord-022526-j9kg00qf 432 11 and and CC cord-022526-j9kg00qf 432 12 intestinal intestinal JJ cord-022526-j9kg00qf 432 13 lymphoid lymphoid JJ cord-022526-j9kg00qf 432 14 organs organ NNS cord-022526-j9kg00qf 432 15 are be VBP cord-022526-j9kg00qf 432 16 among among IN cord-022526-j9kg00qf 432 17 the the DT cord-022526-j9kg00qf 432 18 first first JJ cord-022526-j9kg00qf 432 19 cells cell NNS cord-022526-j9kg00qf 432 20 beyond beyond IN cord-022526-j9kg00qf 432 21 the the DT cord-022526-j9kg00qf 432 22 epithelium epithelium NN cord-022526-j9kg00qf 432 23 to to TO cord-022526-j9kg00qf 432 24 respond respond VB cord-022526-j9kg00qf 432 25 to to IN cord-022526-j9kg00qf 432 26 infection infection NN cord-022526-j9kg00qf 432 27 or or CC cord-022526-j9kg00qf 432 28 injury injury NN cord-022526-j9kg00qf 432 29 . . . cord-022526-j9kg00qf 433 1 Macrophages macrophage NNS cord-022526-j9kg00qf 433 2 are be VBP cord-022526-j9kg00qf 433 3 activated activate VBN cord-022526-j9kg00qf 433 4 by by IN cord-022526-j9kg00qf 433 5 bacterial bacterial JJ cord-022526-j9kg00qf 433 6 products product NNS cord-022526-j9kg00qf 433 7 via via IN cord-022526-j9kg00qf 433 8 pattern pattern NN cord-022526-j9kg00qf 433 9 recognition recognition NN cord-022526-j9kg00qf 433 10 receptors receptor NNS cord-022526-j9kg00qf 433 11 and and CC cord-022526-j9kg00qf 433 12 begin begin VBP cord-022526-j9kg00qf 433 13 to to TO cord-022526-j9kg00qf 433 14 produce produce VB cord-022526-j9kg00qf 433 15 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 433 16 molecules molecule NNS cord-022526-j9kg00qf 433 17 important important JJ cord-022526-j9kg00qf 433 18 for for IN cord-022526-j9kg00qf 433 19 recruiting recruit VBG cord-022526-j9kg00qf 433 20 and and CC cord-022526-j9kg00qf 433 21 activating activate VBG cord-022526-j9kg00qf 433 22 neutrophils neutrophil NNS cord-022526-j9kg00qf 433 23 and and CC cord-022526-j9kg00qf 433 24 monocytes monocyte NNS cord-022526-j9kg00qf 433 25 . . . cord-022526-j9kg00qf 434 1 Pattern pattern NN cord-022526-j9kg00qf 434 2 recognition recognition NN cord-022526-j9kg00qf 434 3 receptors receptor NNS cord-022526-j9kg00qf 434 4 recognize recognize VBP cord-022526-j9kg00qf 434 5 microbial microbial JJ cord-022526-j9kg00qf 434 6 products product NNS cord-022526-j9kg00qf 434 7 ranging range VBG cord-022526-j9kg00qf 434 8 from from IN cord-022526-j9kg00qf 434 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 434 10 to to IN cord-022526-j9kg00qf 434 11 peptidoglycan peptidoglycan NN cord-022526-j9kg00qf 434 12 and and CC cord-022526-j9kg00qf 434 13 even even RB cord-022526-j9kg00qf 434 14 CpG CpG NNP cord-022526-j9kg00qf 434 15 - - HYPH cord-022526-j9kg00qf 434 16 containing contain VBG cord-022526-j9kg00qf 434 17 bacterial bacterial JJ cord-022526-j9kg00qf 434 18 DNA dna NN cord-022526-j9kg00qf 434 19 and and CC cord-022526-j9kg00qf 434 20 signal signal VB cord-022526-j9kg00qf 434 21 the the DT cord-022526-j9kg00qf 434 22 invasion invasion NN cord-022526-j9kg00qf 434 23 by by IN cord-022526-j9kg00qf 434 24 pathogens pathogen NNS cord-022526-j9kg00qf 434 25 . . . cord-022526-j9kg00qf 435 1 Of of IN cord-022526-j9kg00qf 435 2 the the DT cord-022526-j9kg00qf 435 3 pattern pattern NN cord-022526-j9kg00qf 435 4 recognition recognition NN cord-022526-j9kg00qf 435 5 receptors receptor NNS cord-022526-j9kg00qf 435 6 , , , cord-022526-j9kg00qf 435 7 the the DT cord-022526-j9kg00qf 435 8 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 435 9 receptor receptor NN cord-022526-j9kg00qf 435 10 complex complex NN cord-022526-j9kg00qf 435 11 is be VBZ cord-022526-j9kg00qf 435 12 perhaps perhaps RB cord-022526-j9kg00qf 435 13 the the DT cord-022526-j9kg00qf 435 14 best good JJS cord-022526-j9kg00qf 435 15 defined define VBN cord-022526-j9kg00qf 435 16 . . . cord-022526-j9kg00qf 436 1 Lipopolysaccharide Lipopolysaccharide NNP cord-022526-j9kg00qf 436 2 activates activate VBZ cord-022526-j9kg00qf 436 3 macrophages macrophage NNS cord-022526-j9kg00qf 436 4 via via IN cord-022526-j9kg00qf 436 5 the the DT cord-022526-j9kg00qf 436 6 CD14-Toll CD14-Toll NNP cord-022526-j9kg00qf 436 7 - - HYPH cord-022526-j9kg00qf 436 8 like like JJ cord-022526-j9kg00qf 436 9 receptor receptor NN cord-022526-j9kg00qf 436 10 complex complex NN cord-022526-j9kg00qf 436 11 to to TO cord-022526-j9kg00qf 436 12 initiate initiate VB cord-022526-j9kg00qf 436 13 transcription transcription NN cord-022526-j9kg00qf 436 14 of of IN cord-022526-j9kg00qf 436 15 the the DT cord-022526-j9kg00qf 436 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 436 17 cytokines cytokine NNS cord-022526-j9kg00qf 436 18 TNF TNF NNP cord-022526-j9kg00qf 436 19 - - HYPH cord-022526-j9kg00qf 436 20 α α NNP cord-022526-j9kg00qf 436 21 and and CC cord-022526-j9kg00qf 436 22 IL-1β IL-1β NNP cord-022526-j9kg00qf 436 23 , , , cord-022526-j9kg00qf 436 24 which which WDT cord-022526-j9kg00qf 436 25 synergize synergize VBP cord-022526-j9kg00qf 436 26 with with IN cord-022526-j9kg00qf 436 27 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 436 28 to to TO cord-022526-j9kg00qf 436 29 amplify amplify VB cord-022526-j9kg00qf 436 30 the the DT cord-022526-j9kg00qf 436 31 macrophage macrophage NN cord-022526-j9kg00qf 436 32 response response NN cord-022526-j9kg00qf 436 33 . . . cord-022526-j9kg00qf 437 1 10 10 CD cord-022526-j9kg00qf 437 2 Lipopolysaccharide Lipopolysaccharide NNP cord-022526-j9kg00qf 437 3 , , , cord-022526-j9kg00qf 437 4 particularly particularly RB cord-022526-j9kg00qf 437 5 in in IN cord-022526-j9kg00qf 437 6 concert concert NN cord-022526-j9kg00qf 437 7 with with IN cord-022526-j9kg00qf 437 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 437 9 cytokines cytokine NNS cord-022526-j9kg00qf 437 10 , , , cord-022526-j9kg00qf 437 11 stimulates stimulate VBZ cord-022526-j9kg00qf 437 12 macrophages macrophage NNS cord-022526-j9kg00qf 437 13 to to TO cord-022526-j9kg00qf 437 14 produce produce VB cord-022526-j9kg00qf 437 15 copious copious JJ cord-022526-j9kg00qf 437 16 amounts amount NNS cord-022526-j9kg00qf 437 17 of of IN cord-022526-j9kg00qf 437 18 nitric nitric NN cord-022526-j9kg00qf 437 19 oxide oxide NN cord-022526-j9kg00qf 437 20 , , , cord-022526-j9kg00qf 437 21 which which WDT cord-022526-j9kg00qf 437 22 is be VBZ cord-022526-j9kg00qf 437 23 microbicidal microbicidal JJ cord-022526-j9kg00qf 437 24 and and CC cord-022526-j9kg00qf 437 25 vasoactive vasoactive JJ cord-022526-j9kg00qf 437 26 . . . cord-022526-j9kg00qf 438 1 Nitric nitric NN cord-022526-j9kg00qf 438 2 oxide oxide NN cord-022526-j9kg00qf 438 3 and and CC cord-022526-j9kg00qf 438 4 other other JJ cord-022526-j9kg00qf 438 5 nitrogen nitrogen NN cord-022526-j9kg00qf 438 6 radicals radical NNS cord-022526-j9kg00qf 438 7 react react VBP cord-022526-j9kg00qf 438 8 with with IN cord-022526-j9kg00qf 438 9 reactive reactive JJ cord-022526-j9kg00qf 438 10 oxygen oxygen NN cord-022526-j9kg00qf 438 11 intermediates intermediate NNS cord-022526-j9kg00qf 438 12 ( ( -LRB- cord-022526-j9kg00qf 438 13 ROIs roi NNS cord-022526-j9kg00qf 438 14 ) ) -RRB- cord-022526-j9kg00qf 438 15 to to TO cord-022526-j9kg00qf 438 16 produce produce VB cord-022526-j9kg00qf 438 17 some some DT cord-022526-j9kg00qf 438 18 of of IN cord-022526-j9kg00qf 438 19 the the DT cord-022526-j9kg00qf 438 20 most most RBS cord-022526-j9kg00qf 438 21 toxic toxic JJ cord-022526-j9kg00qf 438 22 molecules molecule NNS cord-022526-j9kg00qf 438 23 of of IN cord-022526-j9kg00qf 438 24 the the DT cord-022526-j9kg00qf 438 25 host host NN cord-022526-j9kg00qf 438 26 defense defense NN cord-022526-j9kg00qf 438 27 system system NN cord-022526-j9kg00qf 438 28 : : : cord-022526-j9kg00qf 438 29 the the DT cord-022526-j9kg00qf 438 30 peroxynitrites peroxynitrites NNPS cord-022526-j9kg00qf 438 31 . . . cord-022526-j9kg00qf 439 1 11 11 CD cord-022526-j9kg00qf 440 1 IL-8 IL-8 NNP cord-022526-j9kg00qf 440 2 is be VBZ cord-022526-j9kg00qf 440 3 produced produce VBN cord-022526-j9kg00qf 440 4 as as RB cord-022526-j9kg00qf 440 5 well well RB cord-022526-j9kg00qf 440 6 to to TO cord-022526-j9kg00qf 440 7 recruit recruit VB cord-022526-j9kg00qf 440 8 neutrophils neutrophil NNS cord-022526-j9kg00qf 440 9 . . . cord-022526-j9kg00qf 441 1 As as IN cord-022526-j9kg00qf 441 2 the the DT cord-022526-j9kg00qf 441 3 response response NN cord-022526-j9kg00qf 441 4 progresses progress VBZ cord-022526-j9kg00qf 441 5 , , , cord-022526-j9kg00qf 441 6 other other JJ cord-022526-j9kg00qf 441 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 441 8 mediators mediator NNS cord-022526-j9kg00qf 441 9 , , , cord-022526-j9kg00qf 441 10 particularly particularly RB cord-022526-j9kg00qf 441 11 the the DT cord-022526-j9kg00qf 441 12 arachidonic arachidonic JJ cord-022526-j9kg00qf 441 13 acid acid NN cord-022526-j9kg00qf 441 14 - - HYPH cord-022526-j9kg00qf 441 15 derived derive VBN cord-022526-j9kg00qf 441 16 lipids lipid NNS cord-022526-j9kg00qf 441 17 , , , cord-022526-j9kg00qf 441 18 are be VBP cord-022526-j9kg00qf 441 19 produced produce VBN cord-022526-j9kg00qf 441 20 . . . cord-022526-j9kg00qf 442 1 These these DT cord-022526-j9kg00qf 442 2 lipids lipid NNS cord-022526-j9kg00qf 442 3 have have VBP cord-022526-j9kg00qf 442 4 potent potent JJ cord-022526-j9kg00qf 442 5 vasoactive vasoactive JJ cord-022526-j9kg00qf 442 6 effects effect NNS cord-022526-j9kg00qf 442 7 and and CC cord-022526-j9kg00qf 442 8 are be VBP cord-022526-j9kg00qf 442 9 important important JJ cord-022526-j9kg00qf 442 10 stimuli stimulus NNS cord-022526-j9kg00qf 442 11 of of IN cord-022526-j9kg00qf 442 12 endothelial endothelial JJ cord-022526-j9kg00qf 442 13 cells cell NNS cord-022526-j9kg00qf 442 14 , , , cord-022526-j9kg00qf 442 15 neutrophils neutrophil NNS cord-022526-j9kg00qf 442 16 , , , cord-022526-j9kg00qf 442 17 and and CC cord-022526-j9kg00qf 442 18 platelets platelet NNS cord-022526-j9kg00qf 442 19 . . . cord-022526-j9kg00qf 443 1 Four four CD cord-022526-j9kg00qf 443 2 important important JJ cord-022526-j9kg00qf 443 3 changes change NNS cord-022526-j9kg00qf 443 4 occur occur VBP cord-022526-j9kg00qf 443 5 in in IN cord-022526-j9kg00qf 443 6 the the DT cord-022526-j9kg00qf 443 7 intestinal intestinal JJ cord-022526-j9kg00qf 443 8 vasculature vasculature NN cord-022526-j9kg00qf 443 9 during during IN cord-022526-j9kg00qf 443 10 inflammation inflammation NN cord-022526-j9kg00qf 443 11 : : : cord-022526-j9kg00qf 443 12 1 1 CD cord-022526-j9kg00qf 443 13 . . . cord-022526-j9kg00qf 444 1 Alteration alteration NN cord-022526-j9kg00qf 444 2 of of IN cord-022526-j9kg00qf 444 3 blood blood NN cord-022526-j9kg00qf 444 4 flow flow NN cord-022526-j9kg00qf 444 5 2 2 CD cord-022526-j9kg00qf 444 6 . . . cord-022526-j9kg00qf 445 1 Increased increase VBN cord-022526-j9kg00qf 445 2 vascular vascular JJ cord-022526-j9kg00qf 445 3 permeability permeability NN cord-022526-j9kg00qf 445 4 3 3 CD cord-022526-j9kg00qf 445 5 . . . cord-022526-j9kg00qf 446 1 Increased increase VBN cord-022526-j9kg00qf 446 2 adhesiveness adhesiveness NN cord-022526-j9kg00qf 446 3 of of IN cord-022526-j9kg00qf 446 4 endothelial endothelial JJ cord-022526-j9kg00qf 446 5 cells cell NNS cord-022526-j9kg00qf 446 6 , , , cord-022526-j9kg00qf 446 7 leukocytes leukocyte NNS cord-022526-j9kg00qf 446 8 , , , cord-022526-j9kg00qf 446 9 and and CC cord-022526-j9kg00qf 446 10 platelets platelet NNS cord-022526-j9kg00qf 446 11 4 4 CD cord-022526-j9kg00qf 446 12 . . . cord-022526-j9kg00qf 447 1 Exposure exposure NN cord-022526-j9kg00qf 447 2 of of IN cord-022526-j9kg00qf 447 3 the the DT cord-022526-j9kg00qf 447 4 basement basement NN cord-022526-j9kg00qf 447 5 membrane membrane NN cord-022526-j9kg00qf 447 6 and and CC cord-022526-j9kg00qf 447 7 activation activation NN cord-022526-j9kg00qf 447 8 of of IN cord-022526-j9kg00qf 447 9 the the DT cord-022526-j9kg00qf 447 10 complement complement NN cord-022526-j9kg00qf 447 11 , , , cord-022526-j9kg00qf 447 12 contact contact NN cord-022526-j9kg00qf 447 13 , , , cord-022526-j9kg00qf 447 14 and and CC cord-022526-j9kg00qf 447 15 coagulation coagulation NN cord-022526-j9kg00qf 447 16 cascades cascade NNS cord-022526-j9kg00qf 448 1 A a DT cord-022526-j9kg00qf 448 2 wide wide JJ cord-022526-j9kg00qf 448 3 range range NN cord-022526-j9kg00qf 448 4 of of IN cord-022526-j9kg00qf 448 5 mediators mediator NNS cord-022526-j9kg00qf 448 6 alters alter VBZ cord-022526-j9kg00qf 448 7 blood blood NN cord-022526-j9kg00qf 448 8 flow flow NN cord-022526-j9kg00qf 448 9 during during IN cord-022526-j9kg00qf 448 10 intestinal intestinal JJ cord-022526-j9kg00qf 448 11 tract tract NN cord-022526-j9kg00qf 448 12 inflammation inflammation NN cord-022526-j9kg00qf 448 13 , , , cord-022526-j9kg00qf 448 14 from from IN cord-022526-j9kg00qf 448 15 gasses gas NNS cord-022526-j9kg00qf 448 16 such such JJ cord-022526-j9kg00qf 448 17 as as IN cord-022526-j9kg00qf 448 18 nitric nitric JJ cord-022526-j9kg00qf 448 19 oxide oxide NN cord-022526-j9kg00qf 448 20 ( ( -LRB- cord-022526-j9kg00qf 448 21 a a DT cord-022526-j9kg00qf 448 22 major major JJ cord-022526-j9kg00qf 448 23 vasodilator vasodilator NN cord-022526-j9kg00qf 448 24 of of IN cord-022526-j9kg00qf 448 25 the the DT cord-022526-j9kg00qf 448 26 intestinal intestinal JJ cord-022526-j9kg00qf 448 27 vasculature vasculature NN cord-022526-j9kg00qf 448 28 ) ) -RRB- cord-022526-j9kg00qf 448 29 to to IN cord-022526-j9kg00qf 448 30 lipids lipid NNS cord-022526-j9kg00qf 448 31 ( ( -LRB- cord-022526-j9kg00qf 448 32 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 448 33 , , , cord-022526-j9kg00qf 448 34 leukotrienes leukotriene NNS cord-022526-j9kg00qf 448 35 , , , cord-022526-j9kg00qf 448 36 thromboxanes thromboxane NNS cord-022526-j9kg00qf 448 37 , , , cord-022526-j9kg00qf 448 38 and and CC cord-022526-j9kg00qf 448 39 platelet platelet NN cord-022526-j9kg00qf 448 40 - - HYPH cord-022526-j9kg00qf 448 41 activating activate VBG cord-022526-j9kg00qf 448 42 factor factor NN cord-022526-j9kg00qf 448 43 ) ) -RRB- cord-022526-j9kg00qf 448 44 , , , cord-022526-j9kg00qf 448 45 cytokines cytokine NNS cord-022526-j9kg00qf 448 46 , , , cord-022526-j9kg00qf 448 47 bradykinin bradykinin NN cord-022526-j9kg00qf 448 48 , , , cord-022526-j9kg00qf 448 49 histamine histamine NN cord-022526-j9kg00qf 448 50 , , , cord-022526-j9kg00qf 448 51 and and CC cord-022526-j9kg00qf 448 52 others other NNS cord-022526-j9kg00qf 448 53 . . . cord-022526-j9kg00qf 449 1 The the DT cord-022526-j9kg00qf 449 2 major major JJ cord-022526-j9kg00qf 449 3 sources source NNS cord-022526-j9kg00qf 449 4 for for IN cord-022526-j9kg00qf 449 5 these these DT cord-022526-j9kg00qf 449 6 mediators mediator NNS cord-022526-j9kg00qf 449 7 include include VBP cord-022526-j9kg00qf 449 8 activated activate VBN cord-022526-j9kg00qf 449 9 leukocytes leukocyte NNS cord-022526-j9kg00qf 449 10 , , , cord-022526-j9kg00qf 449 11 endothelial endothelial JJ cord-022526-j9kg00qf 449 12 cells cell NNS cord-022526-j9kg00qf 449 13 , , , cord-022526-j9kg00qf 449 14 epithelial epithelial JJ cord-022526-j9kg00qf 449 15 cells cell NNS cord-022526-j9kg00qf 449 16 , , , cord-022526-j9kg00qf 449 17 and and CC cord-022526-j9kg00qf 449 18 fibroblasts fibroblast NNS cord-022526-j9kg00qf 449 19 . . . cord-022526-j9kg00qf 450 1 The the DT cord-022526-j9kg00qf 450 2 primary primary JJ cord-022526-j9kg00qf 450 3 determinant determinant NN cord-022526-j9kg00qf 450 4 of of IN cord-022526-j9kg00qf 450 5 blood blood NN cord-022526-j9kg00qf 450 6 flow flow NN cord-022526-j9kg00qf 450 7 early early RB cord-022526-j9kg00qf 450 8 in in IN cord-022526-j9kg00qf 450 9 inflammation inflammation NN cord-022526-j9kg00qf 450 10 is be VBZ cord-022526-j9kg00qf 450 11 vascular vascular JJ cord-022526-j9kg00qf 450 12 caliber caliber NN cord-022526-j9kg00qf 450 13 , , , cord-022526-j9kg00qf 450 14 which which WDT cord-022526-j9kg00qf 450 15 initially initially RB cord-022526-j9kg00qf 450 16 decreases decrease VBZ cord-022526-j9kg00qf 450 17 in in IN cord-022526-j9kg00qf 450 18 arterioles arteriole NNS cord-022526-j9kg00qf 450 19 , , , cord-022526-j9kg00qf 450 20 but but CC cord-022526-j9kg00qf 450 21 then then RB cord-022526-j9kg00qf 450 22 quickly quickly RB cord-022526-j9kg00qf 450 23 changes change VBZ cord-022526-j9kg00qf 450 24 to to IN cord-022526-j9kg00qf 450 25 vasodilation vasodilation NN cord-022526-j9kg00qf 450 26 coincident coincident JJ cord-022526-j9kg00qf 450 27 with with IN cord-022526-j9kg00qf 450 28 opening opening NN cord-022526-j9kg00qf 450 29 of of IN cord-022526-j9kg00qf 450 30 new new JJ cord-022526-j9kg00qf 450 31 capillary capillary JJ cord-022526-j9kg00qf 450 32 beds bed NNS cord-022526-j9kg00qf 450 33 , , , cord-022526-j9kg00qf 450 34 increasing increase VBG cord-022526-j9kg00qf 450 35 net net JJ cord-022526-j9kg00qf 450 36 blood blood NN cord-022526-j9kg00qf 450 37 flow flow NN cord-022526-j9kg00qf 450 38 . . . cord-022526-j9kg00qf 451 1 The the DT cord-022526-j9kg00qf 451 2 increase increase NN cord-022526-j9kg00qf 451 3 in in IN cord-022526-j9kg00qf 451 4 blood blood NN cord-022526-j9kg00qf 451 5 flow flow NN cord-022526-j9kg00qf 451 6 is be VBZ cord-022526-j9kg00qf 451 7 short short RB cord-022526-j9kg00qf 451 8 lived live VBN cord-022526-j9kg00qf 451 9 , , , cord-022526-j9kg00qf 451 10 for for IN cord-022526-j9kg00qf 451 11 the the DT cord-022526-j9kg00qf 451 12 viscosity viscosity NN cord-022526-j9kg00qf 451 13 of of IN cord-022526-j9kg00qf 451 14 the the DT cord-022526-j9kg00qf 451 15 blood blood NN cord-022526-j9kg00qf 451 16 increases increase NNS cord-022526-j9kg00qf 451 17 because because IN cord-022526-j9kg00qf 451 18 of of IN cord-022526-j9kg00qf 451 19 fluid fluid JJ cord-022526-j9kg00qf 451 20 loss loss NN cord-022526-j9kg00qf 451 21 and and CC cord-022526-j9kg00qf 451 22 tissue tissue NN cord-022526-j9kg00qf 451 23 edema edema NN cord-022526-j9kg00qf 451 24 through through IN cord-022526-j9kg00qf 451 25 leaky leaky JJ cord-022526-j9kg00qf 451 26 capillaries capillary NNS cord-022526-j9kg00qf 451 27 . . . cord-022526-j9kg00qf 452 1 Leukocyte Leukocyte NNP cord-022526-j9kg00qf 452 2 margination margination NN cord-022526-j9kg00qf 452 3 , , , cord-022526-j9kg00qf 452 4 platelet platelet NN cord-022526-j9kg00qf 452 5 adhesion adhesion NN cord-022526-j9kg00qf 452 6 to to IN cord-022526-j9kg00qf 452 7 endothelial endothelial JJ cord-022526-j9kg00qf 452 8 cells cell NNS cord-022526-j9kg00qf 452 9 and and CC cord-022526-j9kg00qf 452 10 exposed expose VBN cord-022526-j9kg00qf 452 11 matrix matrix NN cord-022526-j9kg00qf 452 12 , , , cord-022526-j9kg00qf 452 13 and and CC cord-022526-j9kg00qf 452 14 areas area NNS cord-022526-j9kg00qf 452 15 of of IN cord-022526-j9kg00qf 452 16 coagulation coagulation NN cord-022526-j9kg00qf 452 17 protein protein NN cord-022526-j9kg00qf 452 18 accumulation accumulation NN cord-022526-j9kg00qf 452 19 further far RBR cord-022526-j9kg00qf 452 20 decrease decrease VB cord-022526-j9kg00qf 452 21 local local JJ cord-022526-j9kg00qf 452 22 circulation circulation NN cord-022526-j9kg00qf 452 23 . . . cord-022526-j9kg00qf 453 1 Inflammatory inflammatory JJ cord-022526-j9kg00qf 453 2 mediator mediator NN cord-022526-j9kg00qf 453 3 actions action NNS cord-022526-j9kg00qf 453 4 on on IN cord-022526-j9kg00qf 453 5 the the DT cord-022526-j9kg00qf 453 6 endothelial endothelial JJ cord-022526-j9kg00qf 453 7 cells cell NNS cord-022526-j9kg00qf 453 8 initially initially RB cord-022526-j9kg00qf 453 9 increase increase VBP cord-022526-j9kg00qf 453 10 vascular vascular JJ cord-022526-j9kg00qf 453 11 permeability permeability NN cord-022526-j9kg00qf 453 12 . . . cord-022526-j9kg00qf 454 1 Histamine histamine NN cord-022526-j9kg00qf 454 2 , , , cord-022526-j9kg00qf 454 3 leukotrienes leukotriene NNS cord-022526-j9kg00qf 454 4 , , , cord-022526-j9kg00qf 454 5 platelet platelet NN cord-022526-j9kg00qf 454 6 - - HYPH cord-022526-j9kg00qf 454 7 activating activate VBG cord-022526-j9kg00qf 454 8 factor factor NN cord-022526-j9kg00qf 454 9 , , , cord-022526-j9kg00qf 454 10 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 454 11 , , , cord-022526-j9kg00qf 454 12 bradykinin bradykinin NN cord-022526-j9kg00qf 454 13 , , , cord-022526-j9kg00qf 454 14 and and CC cord-022526-j9kg00qf 454 15 other other JJ cord-022526-j9kg00qf 454 16 mediators mediator NNS cord-022526-j9kg00qf 454 17 stimulate stimulate VBP cord-022526-j9kg00qf 454 18 endothelial endothelial JJ cord-022526-j9kg00qf 454 19 cell cell NN cord-022526-j9kg00qf 454 20 contraction contraction NN cord-022526-j9kg00qf 454 21 , , , cord-022526-j9kg00qf 454 22 and and CC cord-022526-j9kg00qf 454 23 interendothelial interendothelial JJ cord-022526-j9kg00qf 454 24 gaps gap NNS cord-022526-j9kg00qf 454 25 form form VB cord-022526-j9kg00qf 454 26 . . . cord-022526-j9kg00qf 455 1 12 12 CD cord-022526-j9kg00qf 455 2 , , , cord-022526-j9kg00qf 455 3 13 13 CD cord-022526-j9kg00qf 455 4 This this DT cord-022526-j9kg00qf 455 5 stage stage NN cord-022526-j9kg00qf 455 6 of of IN cord-022526-j9kg00qf 455 7 increased increase VBN cord-022526-j9kg00qf 455 8 vascular vascular JJ cord-022526-j9kg00qf 455 9 permeability permeability NN cord-022526-j9kg00qf 455 10 is be VBZ cord-022526-j9kg00qf 455 11 readily readily RB cord-022526-j9kg00qf 455 12 reversible reversible JJ cord-022526-j9kg00qf 455 13 . . . cord-022526-j9kg00qf 456 1 Concurrently concurrently RB cord-022526-j9kg00qf 456 2 , , , cord-022526-j9kg00qf 456 3 mediators mediator NNS cord-022526-j9kg00qf 456 4 such such JJ cord-022526-j9kg00qf 456 5 as as IN cord-022526-j9kg00qf 456 6 the the DT cord-022526-j9kg00qf 456 7 cytokines cytokine NNS cord-022526-j9kg00qf 456 8 TNF TNF NNP cord-022526-j9kg00qf 456 9 - - HYPH cord-022526-j9kg00qf 456 10 α α NNP cord-022526-j9kg00qf 456 11 and and CC cord-022526-j9kg00qf 456 12 IL-1β IL-1β NNP cord-022526-j9kg00qf 456 13 induce induce VB cord-022526-j9kg00qf 456 14 a a DT cord-022526-j9kg00qf 456 15 structural structural JJ cord-022526-j9kg00qf 456 16 reorganization reorganization NN cord-022526-j9kg00qf 456 17 of of IN cord-022526-j9kg00qf 456 18 the the DT cord-022526-j9kg00qf 456 19 interendothelial interendothelial JJ cord-022526-j9kg00qf 456 20 junctions junction NNS cord-022526-j9kg00qf 456 21 , , , cord-022526-j9kg00qf 456 22 resulting result VBG cord-022526-j9kg00qf 456 23 in in IN cord-022526-j9kg00qf 456 24 frank frank JJ cord-022526-j9kg00qf 456 25 discontinuities discontinuity NNS cord-022526-j9kg00qf 456 26 in in IN cord-022526-j9kg00qf 456 27 the the DT cord-022526-j9kg00qf 456 28 endothelial endothelial JJ cord-022526-j9kg00qf 456 29 monolayer monolayer NN cord-022526-j9kg00qf 456 30 . . . cord-022526-j9kg00qf 457 1 14 14 CD cord-022526-j9kg00qf 458 1 Cytokines cytokine NNS cord-022526-j9kg00qf 458 2 also also RB cord-022526-j9kg00qf 458 3 stimulate stimulate VBP cord-022526-j9kg00qf 458 4 endothelial endothelial JJ cord-022526-j9kg00qf 458 5 cells cell NNS cord-022526-j9kg00qf 458 6 to to TO cord-022526-j9kg00qf 458 7 express express VB cord-022526-j9kg00qf 458 8 adhesion adhesion NN cord-022526-j9kg00qf 458 9 molecules molecule NNS cord-022526-j9kg00qf 458 10 that that WDT cord-022526-j9kg00qf 458 11 support support VBP cord-022526-j9kg00qf 458 12 adhesion adhesion NN cord-022526-j9kg00qf 458 13 of of IN cord-022526-j9kg00qf 458 14 leukocytes leukocyte NNS cord-022526-j9kg00qf 458 15 and and CC cord-022526-j9kg00qf 458 16 platelets platelet NNS cord-022526-j9kg00qf 458 17 , , , cord-022526-j9kg00qf 458 18 15 15 CD cord-022526-j9kg00qf 458 19 leading lead VBG cord-022526-j9kg00qf 458 20 to to IN cord-022526-j9kg00qf 458 21 the the DT cord-022526-j9kg00qf 458 22 next next JJ cord-022526-j9kg00qf 458 23 and and CC cord-022526-j9kg00qf 458 24 perhaps perhaps RB cord-022526-j9kg00qf 458 25 most most RBS cord-022526-j9kg00qf 458 26 devastating devastating JJ cord-022526-j9kg00qf 458 27 event event NN cord-022526-j9kg00qf 458 28 . . . cord-022526-j9kg00qf 459 1 Leukocytes Leukocytes NNP cord-022526-j9kg00qf 459 2 ( ( -LRB- cord-022526-j9kg00qf 459 3 primarily primarily RB cord-022526-j9kg00qf 459 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 459 5 ) ) -RRB- cord-022526-j9kg00qf 459 6 and and CC cord-022526-j9kg00qf 459 7 platelets platelet NNS cord-022526-j9kg00qf 459 8 adhere adhere VBP cord-022526-j9kg00qf 459 9 to to IN cord-022526-j9kg00qf 459 10 exposed expose VBN cord-022526-j9kg00qf 459 11 basement basement NN cord-022526-j9kg00qf 459 12 membranes membrane NNS cord-022526-j9kg00qf 459 13 and and CC cord-022526-j9kg00qf 459 14 activated activate VBD cord-022526-j9kg00qf 459 15 endothelial endothelial JJ cord-022526-j9kg00qf 459 16 cells cell NNS cord-022526-j9kg00qf 459 17 . . . cord-022526-j9kg00qf 460 1 Adherent adherent JJ cord-022526-j9kg00qf 460 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 460 3 and and CC cord-022526-j9kg00qf 460 4 platelets platelet NNS cord-022526-j9kg00qf 460 5 then then RB cord-022526-j9kg00qf 460 6 are be VBP cord-022526-j9kg00qf 460 7 exposed expose VBN cord-022526-j9kg00qf 460 8 to to IN cord-022526-j9kg00qf 460 9 the the DT cord-022526-j9kg00qf 460 10 mediators mediator NNS cord-022526-j9kg00qf 460 11 of of IN cord-022526-j9kg00qf 460 12 inflammation inflammation NN cord-022526-j9kg00qf 460 13 present present JJ cord-022526-j9kg00qf 460 14 in in IN cord-022526-j9kg00qf 460 15 the the DT cord-022526-j9kg00qf 460 16 surrounding surround VBG cord-022526-j9kg00qf 460 17 milieu milieu NN cord-022526-j9kg00qf 460 18 , , , cord-022526-j9kg00qf 460 19 which which WDT cord-022526-j9kg00qf 460 20 activates activate VBZ cord-022526-j9kg00qf 460 21 the the DT cord-022526-j9kg00qf 460 22 cells cell NNS cord-022526-j9kg00qf 460 23 to to TO cord-022526-j9kg00qf 460 24 release release VB cord-022526-j9kg00qf 460 25 oxidants oxidant NNS cord-022526-j9kg00qf 460 26 and and CC cord-022526-j9kg00qf 460 27 proteases protease NNS cord-022526-j9kg00qf 460 28 ( ( -LRB- cord-022526-j9kg00qf 460 29 particularly particularly RB cord-022526-j9kg00qf 460 30 elastase elastase NN cord-022526-j9kg00qf 460 31 ) ) -RRB- cord-022526-j9kg00qf 460 32 that that WDT cord-022526-j9kg00qf 460 33 injure injure VBP cord-022526-j9kg00qf 460 34 the the DT cord-022526-j9kg00qf 460 35 endothelium endothelium NN cord-022526-j9kg00qf 460 36 and and CC cord-022526-j9kg00qf 460 37 have have VB cord-022526-j9kg00qf 460 38 the the DT cord-022526-j9kg00qf 460 39 potential potential NN cord-022526-j9kg00qf 460 40 to to TO cord-022526-j9kg00qf 460 41 cause cause VB cord-022526-j9kg00qf 460 42 irreparable irreparable JJ cord-022526-j9kg00qf 460 43 harm harm NN cord-022526-j9kg00qf 460 44 to to IN cord-022526-j9kg00qf 460 45 the the DT cord-022526-j9kg00qf 460 46 microvasculature microvasculature NN cord-022526-j9kg00qf 460 47 . . . cord-022526-j9kg00qf 461 1 [ [ -LRB- cord-022526-j9kg00qf 461 2 16 16 CD cord-022526-j9kg00qf 461 3 ] ] -RRB- cord-022526-j9kg00qf 461 4 [ [ -LRB- cord-022526-j9kg00qf 461 5 17 17 CD cord-022526-j9kg00qf 461 6 ] ] -RRB- cord-022526-j9kg00qf 461 7 [ [ -LRB- cord-022526-j9kg00qf 461 8 18 18 CD cord-022526-j9kg00qf 461 9 ] ] -RRB- cord-022526-j9kg00qf 461 10 Marginated marginated JJ cord-022526-j9kg00qf 461 11 neutrophils neutrophil NNS cord-022526-j9kg00qf 461 12 begin begin VBP cord-022526-j9kg00qf 461 13 to to TO cord-022526-j9kg00qf 461 14 transmigrate transmigrate VB cord-022526-j9kg00qf 461 15 between between IN cord-022526-j9kg00qf 461 16 endothelial endothelial JJ cord-022526-j9kg00qf 461 17 cells cell NNS cord-022526-j9kg00qf 461 18 ( ( -LRB- cord-022526-j9kg00qf 461 19 as as IN cord-022526-j9kg00qf 461 20 described describe VBN cord-022526-j9kg00qf 461 21 in in IN cord-022526-j9kg00qf 461 22 later later JJ cord-022526-j9kg00qf 461 23 sections section NNS cord-022526-j9kg00qf 461 24 ) ) -RRB- cord-022526-j9kg00qf 461 25 , , , cord-022526-j9kg00qf 461 26 and and CC cord-022526-j9kg00qf 461 27 if if IN cord-022526-j9kg00qf 461 28 their -PRON- PRP$ cord-022526-j9kg00qf 461 29 numbers number NNS cord-022526-j9kg00qf 461 30 SECTION section NN cord-022526-j9kg00qf 461 31 13.2 13.2 CD cord-022526-j9kg00qf 461 32 Pathophysiology pathophysiology NN cord-022526-j9kg00qf 461 33 of of IN cord-022526-j9kg00qf 461 34 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 461 35 Inflammation inflammation NN cord-022526-j9kg00qf 461 36 are be VBP cord-022526-j9kg00qf 461 37 large large JJ cord-022526-j9kg00qf 461 38 enough enough RB cord-022526-j9kg00qf 461 39 , , , cord-022526-j9kg00qf 461 40 they -PRON- PRP cord-022526-j9kg00qf 461 41 disrupt disrupt VBP cord-022526-j9kg00qf 461 42 the the DT cord-022526-j9kg00qf 461 43 integrity integrity NN cord-022526-j9kg00qf 461 44 of of IN cord-022526-j9kg00qf 461 45 the the DT cord-022526-j9kg00qf 461 46 interendothelial interendothelial JJ cord-022526-j9kg00qf 461 47 junctions junction NNS cord-022526-j9kg00qf 461 48 , , , cord-022526-j9kg00qf 461 49 worsening worsen VBG cord-022526-j9kg00qf 461 50 the the DT cord-022526-j9kg00qf 461 51 vascular vascular JJ cord-022526-j9kg00qf 461 52 leakage leakage NN cord-022526-j9kg00qf 461 53 . . . cord-022526-j9kg00qf 462 1 17 17 CD cord-022526-j9kg00qf 462 2 Conceptually conceptually RB cord-022526-j9kg00qf 462 3 , , , cord-022526-j9kg00qf 462 4 these these DT cord-022526-j9kg00qf 462 5 stages stage NNS cord-022526-j9kg00qf 462 6 of of IN cord-022526-j9kg00qf 462 7 enhanced enhance VBN cord-022526-j9kg00qf 462 8 vascular vascular JJ cord-022526-j9kg00qf 462 9 permeability permeability NN cord-022526-j9kg00qf 462 10 can can MD cord-022526-j9kg00qf 462 11 be be VB cord-022526-j9kg00qf 462 12 thought think VBN cord-022526-j9kg00qf 462 13 of of IN cord-022526-j9kg00qf 462 14 as as IN cord-022526-j9kg00qf 462 15 a a DT cord-022526-j9kg00qf 462 16 mechanism mechanism NN cord-022526-j9kg00qf 462 17 to to TO cord-022526-j9kg00qf 462 18 allow allow VB cord-022526-j9kg00qf 462 19 plasma plasma NN cord-022526-j9kg00qf 462 20 proteins protein NNS cord-022526-j9kg00qf 462 21 to to TO cord-022526-j9kg00qf 462 22 enter enter VB cord-022526-j9kg00qf 462 23 the the DT cord-022526-j9kg00qf 462 24 tissues tissue NNS cord-022526-j9kg00qf 462 25 and and CC cord-022526-j9kg00qf 462 26 to to TO cord-022526-j9kg00qf 462 27 potentiate potentiate VB cord-022526-j9kg00qf 462 28 the the DT cord-022526-j9kg00qf 462 29 critical critical JJ cord-022526-j9kg00qf 462 30 influx influx NN cord-022526-j9kg00qf 462 31 of of IN cord-022526-j9kg00qf 462 32 leukocytes leukocyte NNS cord-022526-j9kg00qf 462 33 into into IN cord-022526-j9kg00qf 462 34 tissues tissue NNS cord-022526-j9kg00qf 462 35 . . . cord-022526-j9kg00qf 463 1 However however RB cord-022526-j9kg00qf 463 2 , , , cord-022526-j9kg00qf 463 3 if if IN cord-022526-j9kg00qf 463 4 not not RB cord-022526-j9kg00qf 463 5 regulated regulate VBN cord-022526-j9kg00qf 463 6 precisely precisely RB cord-022526-j9kg00qf 463 7 , , , cord-022526-j9kg00qf 463 8 alterations alteration NNS cord-022526-j9kg00qf 463 9 in in IN cord-022526-j9kg00qf 463 10 hydrostatic hydrostatic JJ cord-022526-j9kg00qf 463 11 and and CC cord-022526-j9kg00qf 463 12 oncotic oncotic JJ cord-022526-j9kg00qf 463 13 forces force NNS cord-022526-j9kg00qf 463 14 and and CC cord-022526-j9kg00qf 463 15 irreversible irreversible JJ cord-022526-j9kg00qf 463 16 damage damage NN cord-022526-j9kg00qf 463 17 to to IN cord-022526-j9kg00qf 463 18 the the DT cord-022526-j9kg00qf 463 19 vascular vascular JJ cord-022526-j9kg00qf 463 20 bed bed NN cord-022526-j9kg00qf 463 21 may may MD cord-022526-j9kg00qf 463 22 have have VB cord-022526-j9kg00qf 463 23 devastating devastating JJ cord-022526-j9kg00qf 463 24 consequences consequence NNS cord-022526-j9kg00qf 463 25 . . . cord-022526-j9kg00qf 464 1 Moreover moreover RB cord-022526-j9kg00qf 464 2 , , , cord-022526-j9kg00qf 464 3 inappropriate inappropriate JJ cord-022526-j9kg00qf 464 4 activation activation NN cord-022526-j9kg00qf 464 5 of of IN cord-022526-j9kg00qf 464 6 plasma plasma NN cord-022526-j9kg00qf 464 7 protein protein NN cord-022526-j9kg00qf 464 8 cascades cascade NNS cord-022526-j9kg00qf 464 9 and and CC cord-022526-j9kg00qf 464 10 leukocytes leukocyte NNS cord-022526-j9kg00qf 464 11 by by IN cord-022526-j9kg00qf 464 12 activated activate VBN cord-022526-j9kg00qf 464 13 endothelium endothelium NN cord-022526-j9kg00qf 464 14 and and CC cord-022526-j9kg00qf 464 15 exposed expose VBN cord-022526-j9kg00qf 464 16 matrix matrix NN cord-022526-j9kg00qf 464 17 proteins protein NNS cord-022526-j9kg00qf 464 18 can can MD cord-022526-j9kg00qf 464 19 contribute contribute VB cord-022526-j9kg00qf 464 20 to to IN cord-022526-j9kg00qf 464 21 systemic systemic JJ cord-022526-j9kg00qf 464 22 inflammation inflammation NN cord-022526-j9kg00qf 464 23 ( ( -LRB- cord-022526-j9kg00qf 464 24 systemic systemic JJ cord-022526-j9kg00qf 464 25 inflammatory inflammatory JJ cord-022526-j9kg00qf 464 26 response response NN cord-022526-j9kg00qf 464 27 syndrome syndrome NN cord-022526-j9kg00qf 464 28 ; ; : cord-022526-j9kg00qf 464 29 see see VB cord-022526-j9kg00qf 464 30 Chapter chapter NN cord-022526-j9kg00qf 464 31 13.7 13.7 CD cord-022526-j9kg00qf 464 32 for for IN cord-022526-j9kg00qf 464 33 more more JJR cord-022526-j9kg00qf 464 34 information information NN cord-022526-j9kg00qf 464 35 ) ) -RRB- cord-022526-j9kg00qf 464 36 characterized characterize VBN cord-022526-j9kg00qf 464 37 by by IN cord-022526-j9kg00qf 464 38 hypotension hypotension NN cord-022526-j9kg00qf 464 39 , , , cord-022526-j9kg00qf 464 40 generalized generalize VBN cord-022526-j9kg00qf 464 41 vascular vascular JJ cord-022526-j9kg00qf 464 42 leak leak NN cord-022526-j9kg00qf 464 43 syndrome syndrome NN cord-022526-j9kg00qf 464 44 , , , cord-022526-j9kg00qf 464 45 and and CC cord-022526-j9kg00qf 464 46 multiorgan multiorgan NNP cord-022526-j9kg00qf 464 47 dysfunction dysfunction NN cord-022526-j9kg00qf 464 48 , , , cord-022526-j9kg00qf 464 49 which which WDT cord-022526-j9kg00qf 464 50 may may MD cord-022526-j9kg00qf 464 51 be be VB cord-022526-j9kg00qf 464 52 fatal fatal JJ cord-022526-j9kg00qf 464 53 . . . cord-022526-j9kg00qf 465 1 Phosphodiesterase Phosphodiesterase NNP cord-022526-j9kg00qf 465 2 inhibitors inhibitor NNS cord-022526-j9kg00qf 465 3 reduce reduce VBP cord-022526-j9kg00qf 465 4 endothelial endothelial JJ cord-022526-j9kg00qf 465 5 permeability permeability NN cord-022526-j9kg00qf 465 6 in in IN cord-022526-j9kg00qf 465 7 ischemia ischemia NN cord-022526-j9kg00qf 465 8 - - HYPH cord-022526-j9kg00qf 465 9 reperfusion reperfusion NN cord-022526-j9kg00qf 465 10 injury injury NN cord-022526-j9kg00qf 465 11 and and CC cord-022526-j9kg00qf 465 12 other other JJ cord-022526-j9kg00qf 465 13 models model NNS cord-022526-j9kg00qf 465 14 of of IN cord-022526-j9kg00qf 465 15 inflammation inflammation NN cord-022526-j9kg00qf 465 16 - - HYPH cord-022526-j9kg00qf 465 17 induced induce VBN cord-022526-j9kg00qf 465 18 vascular vascular JJ cord-022526-j9kg00qf 465 19 leakage leakage NN cord-022526-j9kg00qf 465 20 19 19 CD cord-022526-j9kg00qf 465 21 , , , cord-022526-j9kg00qf 465 22 20 20 CD cord-022526-j9kg00qf 465 23 by by IN cord-022526-j9kg00qf 465 24 increasing increase VBG cord-022526-j9kg00qf 465 25 endothelial endothelial JJ cord-022526-j9kg00qf 465 26 tight tight JJ cord-022526-j9kg00qf 465 27 junction junction NN cord-022526-j9kg00qf 465 28 integrity integrity NN cord-022526-j9kg00qf 465 29 and and CC cord-022526-j9kg00qf 465 30 thus thus RB cord-022526-j9kg00qf 465 31 may may MD cord-022526-j9kg00qf 465 32 be be VB cord-022526-j9kg00qf 465 33 a a DT cord-022526-j9kg00qf 465 34 viable viable JJ cord-022526-j9kg00qf 465 35 therapeutic therapeutic JJ cord-022526-j9kg00qf 465 36 strategy strategy NN cord-022526-j9kg00qf 465 37 to to TO cord-022526-j9kg00qf 465 38 prevent prevent VB cord-022526-j9kg00qf 465 39 or or CC cord-022526-j9kg00qf 465 40 reduce reduce VB cord-022526-j9kg00qf 465 41 the the DT cord-022526-j9kg00qf 465 42 permeability permeability NN cord-022526-j9kg00qf 465 43 alterations alteration NNS cord-022526-j9kg00qf 465 44 associated associate VBN cord-022526-j9kg00qf 465 45 with with IN cord-022526-j9kg00qf 465 46 inflammation inflammation NN cord-022526-j9kg00qf 465 47 . . . cord-022526-j9kg00qf 466 1 Endothelial endothelial NN cord-022526-j9kg00qf 466 2 cells cell NNS cord-022526-j9kg00qf 466 3 respond respond VBP cord-022526-j9kg00qf 466 4 to to IN cord-022526-j9kg00qf 466 5 products product NNS cord-022526-j9kg00qf 466 6 of of IN cord-022526-j9kg00qf 466 7 activated activate VBN cord-022526-j9kg00qf 466 8 epithelial epithelial JJ cord-022526-j9kg00qf 466 9 cells cell NNS cord-022526-j9kg00qf 466 10 and and CC cord-022526-j9kg00qf 466 11 macrophages macrophage NNS cord-022526-j9kg00qf 466 12 in in IN cord-022526-j9kg00qf 466 13 the the DT cord-022526-j9kg00qf 466 14 intestinal intestinal JJ cord-022526-j9kg00qf 466 15 tissue tissue NN cord-022526-j9kg00qf 466 16 to to TO cord-022526-j9kg00qf 466 17 recruit recruit VB cord-022526-j9kg00qf 466 18 cells cell NNS cord-022526-j9kg00qf 466 19 and and CC cord-022526-j9kg00qf 466 20 humoral humoral JJ cord-022526-j9kg00qf 466 21 mediators mediator NNS cord-022526-j9kg00qf 466 22 of of IN cord-022526-j9kg00qf 466 23 inflammation inflammation NN cord-022526-j9kg00qf 466 24 into into IN cord-022526-j9kg00qf 466 25 the the DT cord-022526-j9kg00qf 466 26 tissue tissue NN cord-022526-j9kg00qf 466 27 . . . cord-022526-j9kg00qf 467 1 Activated activate VBN cord-022526-j9kg00qf 467 2 endothelial endothelial JJ cord-022526-j9kg00qf 467 3 cells cell NNS cord-022526-j9kg00qf 467 4 display display VBP cord-022526-j9kg00qf 467 5 a a DT cord-022526-j9kg00qf 467 6 range range NN cord-022526-j9kg00qf 467 7 of of IN cord-022526-j9kg00qf 467 8 molecules molecule NNS cord-022526-j9kg00qf 467 9 critical critical JJ cord-022526-j9kg00qf 467 10 for for IN cord-022526-j9kg00qf 467 11 neutrophil neutrophil NN cord-022526-j9kg00qf 467 12 and and CC cord-022526-j9kg00qf 467 13 platelet platelet NN cord-022526-j9kg00qf 467 14 adhesion adhesion NN cord-022526-j9kg00qf 467 15 . . . cord-022526-j9kg00qf 468 1 Intercellular intercellular JJ cord-022526-j9kg00qf 468 2 permeability permeability NN cord-022526-j9kg00qf 468 3 increases increase VBZ cord-022526-j9kg00qf 468 4 to to TO cord-022526-j9kg00qf 468 5 expose expose VB cord-022526-j9kg00qf 468 6 basement basement NN cord-022526-j9kg00qf 468 7 membrane membrane NN cord-022526-j9kg00qf 468 8 proteins protein NNS cord-022526-j9kg00qf 468 9 that that WDT cord-022526-j9kg00qf 468 10 trigger trigger VBP cord-022526-j9kg00qf 468 11 humoral humoral JJ cord-022526-j9kg00qf 468 12 defense defense NN cord-022526-j9kg00qf 468 13 systems system NNS cord-022526-j9kg00qf 468 14 ( ( -LRB- cord-022526-j9kg00qf 468 15 complement complement NN cord-022526-j9kg00qf 468 16 , , , cord-022526-j9kg00qf 468 17 coagulation coagulation NN cord-022526-j9kg00qf 468 18 , , , cord-022526-j9kg00qf 468 19 and and CC cord-022526-j9kg00qf 468 20 contact contact NN cord-022526-j9kg00qf 468 21 system system NN cord-022526-j9kg00qf 468 22 cascades cascade NNS cord-022526-j9kg00qf 468 23 ) ) -RRB- cord-022526-j9kg00qf 468 24 and and CC cord-022526-j9kg00qf 468 25 to to TO cord-022526-j9kg00qf 468 26 provide provide VB cord-022526-j9kg00qf 468 27 access access NN cord-022526-j9kg00qf 468 28 for for IN cord-022526-j9kg00qf 468 29 these these DT cord-022526-j9kg00qf 468 30 macromolecules macromolecule NNS cord-022526-j9kg00qf 468 31 to to IN cord-022526-j9kg00qf 468 32 the the DT cord-022526-j9kg00qf 468 33 tissue tissue NN cord-022526-j9kg00qf 468 34 . . . cord-022526-j9kg00qf 469 1 Endothelial endothelial JJ cord-022526-j9kg00qf 469 2 cells cell NNS cord-022526-j9kg00qf 469 3 are be VBP cord-022526-j9kg00qf 469 4 an an DT cord-022526-j9kg00qf 469 5 important important JJ cord-022526-j9kg00qf 469 6 source source NN cord-022526-j9kg00qf 469 7 of of IN cord-022526-j9kg00qf 469 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 469 9 mediators mediator NNS cord-022526-j9kg00qf 469 10 that that WDT cord-022526-j9kg00qf 469 11 amplify amplify VBP cord-022526-j9kg00qf 469 12 the the DT cord-022526-j9kg00qf 469 13 response response NN cord-022526-j9kg00qf 469 14 and and CC cord-022526-j9kg00qf 469 15 vasoactive vasoactive JJ cord-022526-j9kg00qf 469 16 substances substance NNS cord-022526-j9kg00qf 469 17 ( ( -LRB- cord-022526-j9kg00qf 469 18 particularly particularly RB cord-022526-j9kg00qf 469 19 nitric nitric JJ cord-022526-j9kg00qf 469 20 oxide oxide NN cord-022526-j9kg00qf 469 21 ) ) -RRB- cord-022526-j9kg00qf 469 22 that that WDT cord-022526-j9kg00qf 469 23 alter alter VBP cord-022526-j9kg00qf 469 24 blood blood NN cord-022526-j9kg00qf 469 25 flow flow NN cord-022526-j9kg00qf 469 26 . . . cord-022526-j9kg00qf 470 1 Infection infection NN cord-022526-j9kg00qf 470 2 or or CC cord-022526-j9kg00qf 470 3 injury injury NN cord-022526-j9kg00qf 470 4 to to IN cord-022526-j9kg00qf 470 5 the the DT cord-022526-j9kg00qf 470 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 470 7 mucosa mucosa NN cord-022526-j9kg00qf 470 8 causes cause VBZ cord-022526-j9kg00qf 470 9 an an DT cord-022526-j9kg00qf 470 10 influx influx NN cord-022526-j9kg00qf 470 11 of of IN cord-022526-j9kg00qf 470 12 leukocytes leukocyte NNS cord-022526-j9kg00qf 470 13 from from IN cord-022526-j9kg00qf 470 14 the the DT cord-022526-j9kg00qf 470 15 blood blood NN cord-022526-j9kg00qf 470 16 that that WDT cord-022526-j9kg00qf 470 17 lay lie VBD cord-022526-j9kg00qf 470 18 the the DT cord-022526-j9kg00qf 470 19 foundation foundation NN cord-022526-j9kg00qf 470 20 of of IN cord-022526-j9kg00qf 470 21 the the DT cord-022526-j9kg00qf 470 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 470 23 response response NN cord-022526-j9kg00qf 470 24 . . . cord-022526-j9kg00qf 471 1 Neutrophils neutrophils NN cord-022526-j9kg00qf 471 2 , , , cord-022526-j9kg00qf 471 3 being be VBG cord-022526-j9kg00qf 471 4 the the DT cord-022526-j9kg00qf 471 5 first first JJ cord-022526-j9kg00qf 471 6 to to TO cord-022526-j9kg00qf 471 7 arrive arrive VB cord-022526-j9kg00qf 471 8 during during IN cord-022526-j9kg00qf 471 9 inflammation inflammation NN cord-022526-j9kg00qf 471 10 , , , cord-022526-j9kg00qf 471 11 have have VBP cord-022526-j9kg00qf 471 12 a a DT cord-022526-j9kg00qf 471 13 dominant dominant JJ cord-022526-j9kg00qf 471 14 role role NN cord-022526-j9kg00qf 471 15 in in IN cord-022526-j9kg00qf 471 16 the the DT cord-022526-j9kg00qf 471 17 acute acute JJ cord-022526-j9kg00qf 471 18 response response NN cord-022526-j9kg00qf 471 19 . . . cord-022526-j9kg00qf 472 1 Within within IN cord-022526-j9kg00qf 472 2 minutes minute NNS cord-022526-j9kg00qf 472 3 , , , cord-022526-j9kg00qf 472 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 472 5 are be VBP cord-022526-j9kg00qf 472 6 recruited recruit VBN cord-022526-j9kg00qf 472 7 into into IN cord-022526-j9kg00qf 472 8 the the DT cord-022526-j9kg00qf 472 9 tissue tissue NN cord-022526-j9kg00qf 472 10 where where WRB cord-022526-j9kg00qf 472 11 they -PRON- PRP cord-022526-j9kg00qf 472 12 are be VBP cord-022526-j9kg00qf 472 13 activated activate VBN cord-022526-j9kg00qf 472 14 to to TO cord-022526-j9kg00qf 472 15 release release VB cord-022526-j9kg00qf 472 16 products product NNS cord-022526-j9kg00qf 472 17 that that IN cord-022526-j9kg00qf 472 18 not not RB cord-022526-j9kg00qf 472 19 only only RB cord-022526-j9kg00qf 472 20 are be VBP cord-022526-j9kg00qf 472 21 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 472 22 and and CC cord-022526-j9kg00qf 472 23 lethal lethal JJ cord-022526-j9kg00qf 472 24 to to IN cord-022526-j9kg00qf 472 25 pathogens pathogen NNS cord-022526-j9kg00qf 472 26 but but CC cord-022526-j9kg00qf 472 27 also also RB cord-022526-j9kg00qf 472 28 may may MD cord-022526-j9kg00qf 472 29 damage damage VB cord-022526-j9kg00qf 472 30 host host NN cord-022526-j9kg00qf 472 31 cells cell NNS cord-022526-j9kg00qf 472 32 and and CC cord-022526-j9kg00qf 472 33 tissues tissue NNS cord-022526-j9kg00qf 472 34 . . . cord-022526-j9kg00qf 473 1 Not not RB cord-022526-j9kg00qf 473 2 surprisingly surprisingly RB cord-022526-j9kg00qf 473 3 , , , cord-022526-j9kg00qf 473 4 much much JJ cord-022526-j9kg00qf 473 5 attention attention NN cord-022526-j9kg00qf 473 6 has have VBZ cord-022526-j9kg00qf 473 7 been be VBN cord-022526-j9kg00qf 473 8 paid pay VBN cord-022526-j9kg00qf 473 9 to to IN cord-022526-j9kg00qf 473 10 the the DT cord-022526-j9kg00qf 473 11 role role NN cord-022526-j9kg00qf 473 12 of of IN cord-022526-j9kg00qf 473 13 neutrophils neutrophil NNS cord-022526-j9kg00qf 473 14 in in IN cord-022526-j9kg00qf 473 15 the the DT cord-022526-j9kg00qf 473 16 pathophysiology pathophysiology NN cord-022526-j9kg00qf 473 17 of of IN cord-022526-j9kg00qf 473 18 many many JJ cord-022526-j9kg00qf 473 19 inflammatory inflammatory JJ cord-022526-j9kg00qf 473 20 conditions condition NNS cord-022526-j9kg00qf 473 21 . . . cord-022526-j9kg00qf 474 1 21 21 CD cord-022526-j9kg00qf 475 1 Neutrophil Neutrophil NNP cord-022526-j9kg00qf 475 2 depletion depletion NN cord-022526-j9kg00qf 475 3 is be VBZ cord-022526-j9kg00qf 475 4 protective protective JJ cord-022526-j9kg00qf 475 5 in in IN cord-022526-j9kg00qf 475 6 many many JJ cord-022526-j9kg00qf 475 7 models model NNS cord-022526-j9kg00qf 475 8 of of IN cord-022526-j9kg00qf 475 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 475 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 475 11 disease disease NN cord-022526-j9kg00qf 475 12 . . . cord-022526-j9kg00qf 476 1 Of of IN cord-022526-j9kg00qf 476 2 interest interest NN cord-022526-j9kg00qf 476 3 to to IN cord-022526-j9kg00qf 476 4 clinicians clinician NNS cord-022526-j9kg00qf 476 5 , , , cord-022526-j9kg00qf 476 6 blockade blockade NN cord-022526-j9kg00qf 476 7 of of IN cord-022526-j9kg00qf 476 8 neutrophil neutrophil NN cord-022526-j9kg00qf 476 9 migration migration NN cord-022526-j9kg00qf 476 10 into into IN cord-022526-j9kg00qf 476 11 inflamed inflamed JJ cord-022526-j9kg00qf 476 12 tissues tissue NNS cord-022526-j9kg00qf 476 13 prevents prevent VBZ cord-022526-j9kg00qf 476 14 many many JJ cord-022526-j9kg00qf 476 15 of of IN cord-022526-j9kg00qf 476 16 the the DT cord-022526-j9kg00qf 476 17 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 476 18 events event NNS cord-022526-j9kg00qf 476 19 associated associate VBN cord-022526-j9kg00qf 476 20 with with IN cord-022526-j9kg00qf 476 21 infectious infectious JJ cord-022526-j9kg00qf 476 22 enteritis enteritis NN cord-022526-j9kg00qf 476 23 , , , cord-022526-j9kg00qf 476 24 ischemia ischemia NN cord-022526-j9kg00qf 476 25 - - HYPH cord-022526-j9kg00qf 476 26 reperfusion reperfusion NN cord-022526-j9kg00qf 476 27 injury injury NN cord-022526-j9kg00qf 476 28 , , , cord-022526-j9kg00qf 476 29 and and CC cord-022526-j9kg00qf 476 30 other other JJ cord-022526-j9kg00qf 476 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 476 32 diseases disease NNS cord-022526-j9kg00qf 476 33 . . . cord-022526-j9kg00qf 477 1 16 16 CD cord-022526-j9kg00qf 477 2 , , , cord-022526-j9kg00qf 477 3 [ [ -LRB- cord-022526-j9kg00qf 477 4 22 22 CD cord-022526-j9kg00qf 477 5 ] ] -RRB- cord-022526-j9kg00qf 477 6 [ [ -LRB- cord-022526-j9kg00qf 477 7 23 23 CD cord-022526-j9kg00qf 477 8 ] ] -RRB- cord-022526-j9kg00qf 478 1 [ [ -LRB- cord-022526-j9kg00qf 478 2 24 24 CD cord-022526-j9kg00qf 478 3 ] ] -RRB- cord-022526-j9kg00qf 478 4 [ [ -LRB- cord-022526-j9kg00qf 478 5 25 25 CD cord-022526-j9kg00qf 478 6 ] ] -RRB- cord-022526-j9kg00qf 478 7 [ [ -LRB- cord-022526-j9kg00qf 478 8 26 26 CD cord-022526-j9kg00qf 478 9 ] ] -RRB- cord-022526-j9kg00qf 479 1 Neutrophil Neutrophil NNP cord-022526-j9kg00qf 479 2 transendothelial transendothelial JJ cord-022526-j9kg00qf 479 3 migration migration NN cord-022526-j9kg00qf 479 4 is be VBZ cord-022526-j9kg00qf 479 5 a a DT cord-022526-j9kg00qf 479 6 multistep multistep JJ cord-022526-j9kg00qf 479 7 process process NN cord-022526-j9kg00qf 479 8 that that WDT cord-022526-j9kg00qf 479 9 is be VBZ cord-022526-j9kg00qf 479 10 temporally temporally RB cord-022526-j9kg00qf 479 11 and and CC cord-022526-j9kg00qf 479 12 spatially spatially RB cord-022526-j9kg00qf 479 13 regulated regulated JJ cord-022526-j9kg00qf 479 14 and and CC cord-022526-j9kg00qf 479 15 has have VBZ cord-022526-j9kg00qf 479 16 a a DT cord-022526-j9kg00qf 479 17 degree degree NN cord-022526-j9kg00qf 479 18 of of IN cord-022526-j9kg00qf 479 19 cell cell NN cord-022526-j9kg00qf 479 20 type type NN cord-022526-j9kg00qf 479 21 specificity specificity NN cord-022526-j9kg00qf 479 22 ( ( -LRB- cord-022526-j9kg00qf 479 23 Figure figure NN cord-022526-j9kg00qf 479 24 13.2 13.2 CD cord-022526-j9kg00qf 479 25 - - HYPH cord-022526-j9kg00qf 479 26 1 1 CD cord-022526-j9kg00qf 479 27 ) ) -RRB- cord-022526-j9kg00qf 479 28 . . . cord-022526-j9kg00qf 480 1 The the DT cord-022526-j9kg00qf 480 2 predominant predominant JJ cord-022526-j9kg00qf 480 3 sites site NNS cord-022526-j9kg00qf 480 4 of of IN cord-022526-j9kg00qf 480 5 neutrophil neutrophil NN cord-022526-j9kg00qf 480 6 transendothelial transendothelial JJ cord-022526-j9kg00qf 480 7 migration migration NN cord-022526-j9kg00qf 480 8 are be VBP cord-022526-j9kg00qf 480 9 in in IN cord-022526-j9kg00qf 480 10 the the DT cord-022526-j9kg00qf 480 11 postcapillary postcapillary JJ cord-022526-j9kg00qf 480 12 venules venule NNS cord-022526-j9kg00qf 480 13 and and CC cord-022526-j9kg00qf 480 14 , , , cord-022526-j9kg00qf 480 15 in in IN cord-022526-j9kg00qf 480 16 some some DT cord-022526-j9kg00qf 480 17 tissues tissue NNS cord-022526-j9kg00qf 480 18 , , , cord-022526-j9kg00qf 480 19 the the DT cord-022526-j9kg00qf 480 20 capillaries capillary NNS cord-022526-j9kg00qf 480 21 . . . cord-022526-j9kg00qf 481 1 Endothelial endothelial JJ cord-022526-j9kg00qf 481 2 cells cell NNS cord-022526-j9kg00qf 481 3 in in IN cord-022526-j9kg00qf 481 4 these these DT cord-022526-j9kg00qf 481 5 vessels vessel NNS cord-022526-j9kg00qf 481 6 respond respond VBP cord-022526-j9kg00qf 481 7 to to IN cord-022526-j9kg00qf 481 8 cytokines cytokine NNS cord-022526-j9kg00qf 481 9 and and CC cord-022526-j9kg00qf 481 10 other other JJ cord-022526-j9kg00qf 481 11 soluble soluble JJ cord-022526-j9kg00qf 481 12 signals signal NNS cord-022526-j9kg00qf 481 13 by by IN cord-022526-j9kg00qf 481 14 expressing express VBG cord-022526-j9kg00qf 481 15 molecules molecule NNS cord-022526-j9kg00qf 481 16 that that WDT cord-022526-j9kg00qf 481 17 promote promote VBP cord-022526-j9kg00qf 481 18 neutrophil neutrophil NN cord-022526-j9kg00qf 481 19 adhesion adhesion NN cord-022526-j9kg00qf 481 20 and and CC cord-022526-j9kg00qf 481 21 transmigration transmigration NN cord-022526-j9kg00qf 481 22 , , , cord-022526-j9kg00qf 481 23 including include VBG cord-022526-j9kg00qf 481 24 selectins selectin NNS cord-022526-j9kg00qf 481 25 and and CC cord-022526-j9kg00qf 481 26 counterreceptors counterreceptor NNS cord-022526-j9kg00qf 481 27 for for IN cord-022526-j9kg00qf 481 28 integrins integrin NNS cord-022526-j9kg00qf 481 29 . . . cord-022526-j9kg00qf 482 1 As as IN cord-022526-j9kg00qf 482 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 482 3 flow flow VBP cord-022526-j9kg00qf 482 4 through through IN cord-022526-j9kg00qf 482 5 these these DT cord-022526-j9kg00qf 482 6 vessels vessel NNS cord-022526-j9kg00qf 482 7 , , , cord-022526-j9kg00qf 482 8 they -PRON- PRP cord-022526-j9kg00qf 482 9 are be VBP cord-022526-j9kg00qf 482 10 first first RB cord-022526-j9kg00qf 482 11 tethered tethered JJ cord-022526-j9kg00qf 482 12 to to IN cord-022526-j9kg00qf 482 13 activated activate VBN cord-022526-j9kg00qf 482 14 endothelium endothelium NN cord-022526-j9kg00qf 482 15 . . . cord-022526-j9kg00qf 483 1 Tethering tethering NN cord-022526-j9kg00qf 483 2 is be VBZ cord-022526-j9kg00qf 483 3 mediated mediate VBN cord-022526-j9kg00qf 483 4 by by IN cord-022526-j9kg00qf 483 5 selectin selectin NNP cord-022526-j9kg00qf 483 6 molecules molecule NNS cord-022526-j9kg00qf 483 7 expressed express VBD cord-022526-j9kg00qf 483 8 on on IN cord-022526-j9kg00qf 483 9 neutrophils neutrophil NNS cord-022526-j9kg00qf 483 10 ( ( -LRB- cord-022526-j9kg00qf 483 11 L L NNP cord-022526-j9kg00qf 483 12 - - HYPH cord-022526-j9kg00qf 483 13 selectin selectin NNP cord-022526-j9kg00qf 483 14 ) ) -RRB- cord-022526-j9kg00qf 483 15 and and CC cord-022526-j9kg00qf 483 16 on on IN cord-022526-j9kg00qf 483 17 activated activate VBN cord-022526-j9kg00qf 483 18 endothelial endothelial JJ cord-022526-j9kg00qf 483 19 cells cell NNS cord-022526-j9kg00qf 483 20 ( ( -LRB- cord-022526-j9kg00qf 483 21 P p NN cord-022526-j9kg00qf 483 22 - - , cord-022526-j9kg00qf 483 23 and and CC cord-022526-j9kg00qf 483 24 E E NNS cord-022526-j9kg00qf 483 25 - - NN cord-022526-j9kg00qf 483 26 selectins selectin NNS cord-022526-j9kg00qf 483 27 ) ) -RRB- cord-022526-j9kg00qf 483 28 that that WDT cord-022526-j9kg00qf 483 29 bind bind VBP cord-022526-j9kg00qf 483 30 to to IN cord-022526-j9kg00qf 483 31 P p NN cord-022526-j9kg00qf 483 32 - - HYPH cord-022526-j9kg00qf 483 33 selectin selectin NN cord-022526-j9kg00qf 483 34 glycoprotein glycoprotein NN cord-022526-j9kg00qf 483 35 ligand-1 ligand-1 NNP cord-022526-j9kg00qf 483 36 ( ( -LRB- cord-022526-j9kg00qf 483 37 PSGL-1 PSGL-1 NNP cord-022526-j9kg00qf 483 38 ) ) -RRB- cord-022526-j9kg00qf 483 39 , , . cord-022526-j9kg00qf 484 1 E E NNP cord-022526-j9kg00qf 484 2 - - NN cord-022526-j9kg00qf 484 3 selectin selectin JJ cord-022526-j9kg00qf 484 4 ligand-1 ligand-1 NNP cord-022526-j9kg00qf 484 5 ( ( -LRB- cord-022526-j9kg00qf 484 6 ESL-1 ESL-1 NNP cord-022526-j9kg00qf 484 7 ) ) -RRB- cord-022526-j9kg00qf 484 8 , , , cord-022526-j9kg00qf 484 9 and and CC cord-022526-j9kg00qf 484 10 other other JJ cord-022526-j9kg00qf 484 11 mucin mucin NN cord-022526-j9kg00qf 484 12 counterreceptors counterreceptors NN cord-022526-j9kg00qf 484 13 . . . cord-022526-j9kg00qf 485 1 27 27 CD cord-022526-j9kg00qf 486 1 , , , cord-022526-j9kg00qf 486 2 28 28 CD cord-022526-j9kg00qf 486 3 Tethering tethering NN cord-022526-j9kg00qf 486 4 functions function NNS cord-022526-j9kg00qf 486 5 to to TO cord-022526-j9kg00qf 486 6 increase increase VB cord-022526-j9kg00qf 486 7 the the DT cord-022526-j9kg00qf 486 8 exposure exposure NN cord-022526-j9kg00qf 486 9 of of IN cord-022526-j9kg00qf 486 10 the the DT cord-022526-j9kg00qf 486 11 neutrophil neutrophil NN cord-022526-j9kg00qf 486 12 to to IN cord-022526-j9kg00qf 486 13 activating activate VBG cord-022526-j9kg00qf 486 14 chemokines chemokine NNS cord-022526-j9kg00qf 486 15 presented present VBN cord-022526-j9kg00qf 486 16 on on IN cord-022526-j9kg00qf 486 17 the the DT cord-022526-j9kg00qf 486 18 surface surface NN cord-022526-j9kg00qf 486 19 of of IN cord-022526-j9kg00qf 486 20 the the DT cord-022526-j9kg00qf 486 21 endothelial endothelial JJ cord-022526-j9kg00qf 486 22 cells cell NNS cord-022526-j9kg00qf 486 23 . . . cord-022526-j9kg00qf 487 1 Stimulation stimulation NN cord-022526-j9kg00qf 487 2 of of IN cord-022526-j9kg00qf 487 3 neutrophils neutrophil NNS cord-022526-j9kg00qf 487 4 by by IN cord-022526-j9kg00qf 487 5 IL-8 IL-8 NNP cord-022526-j9kg00qf 487 6 and and CC cord-022526-j9kg00qf 487 7 other other JJ cord-022526-j9kg00qf 487 8 chemokines chemokine NNS cord-022526-j9kg00qf 487 9 activates activate VBZ cord-022526-j9kg00qf 487 10 the the DT cord-022526-j9kg00qf 487 11 second second JJ cord-022526-j9kg00qf 487 12 step step NN cord-022526-j9kg00qf 487 13 of of IN cord-022526-j9kg00qf 487 14 transendothelial transendothelial JJ cord-022526-j9kg00qf 487 15 migration migration NN cord-022526-j9kg00qf 487 16 . . . cord-022526-j9kg00qf 488 1 Chemokine chemokine JJ cord-022526-j9kg00qf 488 2 binding bind VBG cord-022526-j9kg00qf 488 3 to to IN cord-022526-j9kg00qf 488 4 their -PRON- PRP$ cord-022526-j9kg00qf 488 5 receptors receptor NNS cord-022526-j9kg00qf 488 6 on on IN cord-022526-j9kg00qf 488 7 the the DT cord-022526-j9kg00qf 488 8 neutrophil neutrophil NN cord-022526-j9kg00qf 488 9 generates generate VBZ cord-022526-j9kg00qf 488 10 signals signal NNS cord-022526-j9kg00qf 488 11 that that WDT cord-022526-j9kg00qf 488 12 activate activate VBP cord-022526-j9kg00qf 488 13 the the DT cord-022526-j9kg00qf 488 14 binding binding NN cord-022526-j9kg00qf 488 15 of of IN cord-022526-j9kg00qf 488 16 integrin integrin JJ cord-022526-j9kg00qf 488 17 adhesion adhesion NN cord-022526-j9kg00qf 488 18 receptors receptor NNS cord-022526-j9kg00qf 488 19 to to IN cord-022526-j9kg00qf 488 20 their -PRON- PRP$ cord-022526-j9kg00qf 488 21 ligands ligand NNS cord-022526-j9kg00qf 488 22 , , , cord-022526-j9kg00qf 488 23 called call VBN cord-022526-j9kg00qf 488 24 intracellular intracellular JJ cord-022526-j9kg00qf 488 25 adhesion adhesion NN cord-022526-j9kg00qf 488 26 molecules molecule NNS cord-022526-j9kg00qf 488 27 or or CC cord-022526-j9kg00qf 488 28 vascular vascular JJ cord-022526-j9kg00qf 488 29 cell cell NN cord-022526-j9kg00qf 488 30 adhesion adhesion NN cord-022526-j9kg00qf 488 31 molecules molecule NNS cord-022526-j9kg00qf 488 32 expressed express VBN cord-022526-j9kg00qf 488 33 on on IN cord-022526-j9kg00qf 488 34 endothelial endothelial JJ cord-022526-j9kg00qf 488 35 cells cell NNS cord-022526-j9kg00qf 488 36 in in IN cord-022526-j9kg00qf 488 37 inflamed inflamed JJ cord-022526-j9kg00qf 488 38 mucosa mucosa NN cord-022526-j9kg00qf 488 39 . . . cord-022526-j9kg00qf 489 1 Integrin Integrin NNP cord-022526-j9kg00qf 489 2 ligation ligation NN cord-022526-j9kg00qf 489 3 to to IN cord-022526-j9kg00qf 489 4 cellular cellular JJ cord-022526-j9kg00qf 489 5 adhesion adhesion NN cord-022526-j9kg00qf 489 6 molecules molecule NNS cord-022526-j9kg00qf 489 7 arrests arrest VBZ cord-022526-j9kg00qf 489 8 the the DT cord-022526-j9kg00qf 489 9 tethered tethered JJ cord-022526-j9kg00qf 489 10 neutrophils neutrophil NNS cord-022526-j9kg00qf 489 11 , , , cord-022526-j9kg00qf 489 12 resulting result VBG cord-022526-j9kg00qf 489 13 in in IN cord-022526-j9kg00qf 489 14 firm firm JJ cord-022526-j9kg00qf 489 15 adhesion adhesion NN cord-022526-j9kg00qf 489 16 to to IN cord-022526-j9kg00qf 489 17 the the DT cord-022526-j9kg00qf 489 18 endothelium endothelium NN cord-022526-j9kg00qf 489 19 . . . cord-022526-j9kg00qf 490 1 Of of IN cord-022526-j9kg00qf 490 2 the the DT cord-022526-j9kg00qf 490 3 integrins integrin NNS cord-022526-j9kg00qf 490 4 expressed express VBN cord-022526-j9kg00qf 490 5 on on IN cord-022526-j9kg00qf 490 6 neutrophils neutrophil NNS cord-022526-j9kg00qf 490 7 , , , cord-022526-j9kg00qf 490 8 the the DT cord-022526-j9kg00qf 490 9 β β NN cord-022526-j9kg00qf 490 10 2 2 CD cord-022526-j9kg00qf 490 11 integrins integrin NNS cord-022526-j9kg00qf 490 12 have have VBP cord-022526-j9kg00qf 490 13 a a DT cord-022526-j9kg00qf 490 14 particularly particularly RB cord-022526-j9kg00qf 490 15 important important JJ cord-022526-j9kg00qf 490 16 role role NN cord-022526-j9kg00qf 490 17 in in IN cord-022526-j9kg00qf 490 18 transendothelial transendothelial JJ cord-022526-j9kg00qf 490 19 migration migration NN cord-022526-j9kg00qf 490 20 . . . cord-022526-j9kg00qf 491 1 Calves calf NNS cord-022526-j9kg00qf 491 2 and and CC cord-022526-j9kg00qf 491 3 human human JJ cord-022526-j9kg00qf 491 4 beings being NNS cord-022526-j9kg00qf 491 5 with with IN cord-022526-j9kg00qf 491 6 a a DT cord-022526-j9kg00qf 491 7 disorder disorder NN cord-022526-j9kg00qf 491 8 known know VBN cord-022526-j9kg00qf 491 9 as as IN cord-022526-j9kg00qf 491 10 leukocyte leukocyte NN cord-022526-j9kg00qf 491 11 adhesion adhesion NN cord-022526-j9kg00qf 491 12 deficiency deficiency NN cord-022526-j9kg00qf 491 13 illustrate illustrate VBP cord-022526-j9kg00qf 491 14 the the DT cord-022526-j9kg00qf 491 15 requirement requirement NN cord-022526-j9kg00qf 491 16 for for IN cord-022526-j9kg00qf 491 17 β β NN cord-022526-j9kg00qf 491 18 2 2 CD cord-022526-j9kg00qf 491 19 integrinmediated integrinmediate VBN cord-022526-j9kg00qf 491 20 adhesion adhesion NN cord-022526-j9kg00qf 491 21 in in IN cord-022526-j9kg00qf 491 22 neutrophil neutrophil NN cord-022526-j9kg00qf 491 23 function function NN cord-022526-j9kg00qf 491 24 . . . cord-022526-j9kg00qf 492 1 Leukocyte Leukocyte NNP cord-022526-j9kg00qf 492 2 adhesion adhesion NN cord-022526-j9kg00qf 492 3 deficiency deficiency NN cord-022526-j9kg00qf 492 4 results result VBZ cord-022526-j9kg00qf 492 5 from from IN cord-022526-j9kg00qf 492 6 an an DT cord-022526-j9kg00qf 492 7 autosomal autosomal JJ cord-022526-j9kg00qf 492 8 recessive recessive JJ cord-022526-j9kg00qf 492 9 trait trait NN cord-022526-j9kg00qf 492 10 causing cause VBG cord-022526-j9kg00qf 492 11 the the DT cord-022526-j9kg00qf 492 12 lack lack NN cord-022526-j9kg00qf 492 13 of of IN cord-022526-j9kg00qf 492 14 the the DT cord-022526-j9kg00qf 492 15 β β NN cord-022526-j9kg00qf 492 16 2 2 CD cord-022526-j9kg00qf 492 17 integrin integrin JJ cord-022526-j9kg00qf 492 18 expression expression NN cord-022526-j9kg00qf 492 19 . . . cord-022526-j9kg00qf 493 1 The the DT cord-022526-j9kg00qf 493 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 493 3 from from IN cord-022526-j9kg00qf 493 4 these these DT cord-022526-j9kg00qf 493 5 individuals individual NNS cord-022526-j9kg00qf 493 6 can can MD cord-022526-j9kg00qf 493 7 not not RB cord-022526-j9kg00qf 493 8 migrate migrate VB cord-022526-j9kg00qf 493 9 into into IN cord-022526-j9kg00qf 493 10 most most JJS cord-022526-j9kg00qf 493 11 tissues tissue NNS cord-022526-j9kg00qf 493 12 and and CC cord-022526-j9kg00qf 493 13 do do VBP cord-022526-j9kg00qf 493 14 not not RB cord-022526-j9kg00qf 493 15 function function VB cord-022526-j9kg00qf 493 16 normally normally RB cord-022526-j9kg00qf 493 17 , , , cord-022526-j9kg00qf 493 18 resulting result VBG cord-022526-j9kg00qf 493 19 in in IN cord-022526-j9kg00qf 493 20 poor poor JJ cord-022526-j9kg00qf 493 21 tissue tissue NN cord-022526-j9kg00qf 493 22 healing healing NN cord-022526-j9kg00qf 493 23 and and CC cord-022526-j9kg00qf 493 24 profound profound JJ cord-022526-j9kg00qf 493 25 susceptibility susceptibility NN cord-022526-j9kg00qf 493 26 to to IN cord-022526-j9kg00qf 493 27 infection infection NN cord-022526-j9kg00qf 493 28 , , , cord-022526-j9kg00qf 493 29 especially especially RB cord-022526-j9kg00qf 493 30 at at IN cord-022526-j9kg00qf 493 31 epithelial epithelial JJ cord-022526-j9kg00qf 493 32 barriers barrier NNS cord-022526-j9kg00qf 493 33 . . . cord-022526-j9kg00qf 494 1 29 29 CD cord-022526-j9kg00qf 494 2 , , , cord-022526-j9kg00qf 494 3 30 30 CD cord-022526-j9kg00qf 494 4 Other other JJ cord-022526-j9kg00qf 494 5 integrins integrin NNS cord-022526-j9kg00qf 494 6 also also RB cord-022526-j9kg00qf 494 7 have have VBP cord-022526-j9kg00qf 494 8 a a DT cord-022526-j9kg00qf 494 9 role role NN cord-022526-j9kg00qf 494 10 in in IN cord-022526-j9kg00qf 494 11 transendothelial transendothelial JJ cord-022526-j9kg00qf 494 12 migration migration NN cord-022526-j9kg00qf 494 13 . . . cord-022526-j9kg00qf 495 1 β β NN cord-022526-j9kg00qf 495 2 1 1 CD cord-022526-j9kg00qf 495 3 Integrins Integrins NNPS cord-022526-j9kg00qf 495 4 mediate mediate VBP cord-022526-j9kg00qf 495 5 transendothelial transendothelial JJ cord-022526-j9kg00qf 495 6 migration migration NN cord-022526-j9kg00qf 495 7 in in IN cord-022526-j9kg00qf 495 8 some some DT cord-022526-j9kg00qf 495 9 cells cell NNS cord-022526-j9kg00qf 495 10 and and CC cord-022526-j9kg00qf 495 11 seem seem VBP cord-022526-j9kg00qf 495 12 to to TO cord-022526-j9kg00qf 495 13 be be VB cord-022526-j9kg00qf 495 14 particularly particularly RB cord-022526-j9kg00qf 495 15 important important JJ cord-022526-j9kg00qf 495 16 for for IN cord-022526-j9kg00qf 495 17 mediating mediate VBG cord-022526-j9kg00qf 495 18 emigration emigration NN cord-022526-j9kg00qf 495 19 of of IN cord-022526-j9kg00qf 495 20 monocytes monocyte NNS cord-022526-j9kg00qf 495 21 into into IN cord-022526-j9kg00qf 495 22 many many JJ cord-022526-j9kg00qf 495 23 tissues tissue NNS cord-022526-j9kg00qf 495 24 . . . cord-022526-j9kg00qf 496 1 31 31 CD cord-022526-j9kg00qf 497 1 Following follow VBG cord-022526-j9kg00qf 497 2 this this DT cord-022526-j9kg00qf 497 3 firm firm JJ cord-022526-j9kg00qf 497 4 adhesion adhesion NN cord-022526-j9kg00qf 497 5 step step NN cord-022526-j9kg00qf 497 6 , , , cord-022526-j9kg00qf 497 7 neutrophils neutrophil NNS cord-022526-j9kg00qf 497 8 migrate migrate VBP cord-022526-j9kg00qf 497 9 through through IN cord-022526-j9kg00qf 497 10 the the DT cord-022526-j9kg00qf 497 11 endothelium endothelium NN cord-022526-j9kg00qf 497 12 along along IN cord-022526-j9kg00qf 497 13 a a DT cord-022526-j9kg00qf 497 14 chemotactic chemotactic JJ cord-022526-j9kg00qf 497 15 gradient gradient NN cord-022526-j9kg00qf 497 16 of of IN cord-022526-j9kg00qf 497 17 IL-8 IL-8 NNP cord-022526-j9kg00qf 497 18 and and CC cord-022526-j9kg00qf 497 19 other other JJ cord-022526-j9kg00qf 497 20 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 497 21 such such JJ cord-022526-j9kg00qf 497 22 as as IN cord-022526-j9kg00qf 497 23 leukotriene leukotriene NN cord-022526-j9kg00qf 497 24 B B NNP cord-022526-j9kg00qf 497 25 4 4 CD cord-022526-j9kg00qf 497 26 . . . cord-022526-j9kg00qf 498 1 3 3 CD cord-022526-j9kg00qf 498 2 , , , cord-022526-j9kg00qf 498 3 17 17 CD cord-022526-j9kg00qf 498 4 , , , cord-022526-j9kg00qf 498 5 32 32 CD cord-022526-j9kg00qf 498 6 Neutrophils neutrophil NNS cord-022526-j9kg00qf 498 7 migrate migrate VBP cord-022526-j9kg00qf 498 8 across across IN cord-022526-j9kg00qf 498 9 the the DT cord-022526-j9kg00qf 498 10 endothelial endothelial JJ cord-022526-j9kg00qf 498 11 monolayer monolayer NN cord-022526-j9kg00qf 498 12 at at IN cord-022526-j9kg00qf 498 13 intercellular intercellular JJ cord-022526-j9kg00qf 498 14 junctions junction NNS cord-022526-j9kg00qf 498 15 via via IN cord-022526-j9kg00qf 498 16 a a DT cord-022526-j9kg00qf 498 17 mechanism mechanism NN cord-022526-j9kg00qf 498 18 involving involve VBG cord-022526-j9kg00qf 498 19 a a DT cord-022526-j9kg00qf 498 20 series series NN cord-022526-j9kg00qf 498 21 of of IN cord-022526-j9kg00qf 498 22 integrin integrin NN cord-022526-j9kg00qf 498 23 - - HYPH cord-022526-j9kg00qf 498 24 ligand ligand NN cord-022526-j9kg00qf 498 25 interactions interaction NNS cord-022526-j9kg00qf 498 26 mediated mediate VBN cord-022526-j9kg00qf 498 27 by by IN cord-022526-j9kg00qf 498 28 β β NN cord-022526-j9kg00qf 498 29 2 2 CD cord-022526-j9kg00qf 498 30 and and CC cord-022526-j9kg00qf 498 31 β β NN cord-022526-j9kg00qf 498 32 1 1 CD cord-022526-j9kg00qf 498 33 integrins integrin NNS cord-022526-j9kg00qf 498 34 and and CC cord-022526-j9kg00qf 498 35 other other JJ cord-022526-j9kg00qf 498 36 adhesion adhesion NN cord-022526-j9kg00qf 498 37 molecules molecule NNS cord-022526-j9kg00qf 498 38 28 28 CD cord-022526-j9kg00qf 498 39 that that WDT cord-022526-j9kg00qf 498 40 is be VBZ cord-022526-j9kg00qf 498 41 generally generally RB cord-022526-j9kg00qf 498 42 capable capable JJ cord-022526-j9kg00qf 498 43 of of IN cord-022526-j9kg00qf 498 44 maintaining maintain VBG cord-022526-j9kg00qf 498 45 the the DT cord-022526-j9kg00qf 498 46 integrity integrity NN cord-022526-j9kg00qf 498 47 of of IN cord-022526-j9kg00qf 498 48 the the DT cord-022526-j9kg00qf 498 49 endothelial endothelial JJ cord-022526-j9kg00qf 498 50 barrier barrier NN cord-022526-j9kg00qf 498 51 . . . cord-022526-j9kg00qf 499 1 33 33 CD cord-022526-j9kg00qf 500 1 However however RB cord-022526-j9kg00qf 500 2 , , , cord-022526-j9kg00qf 500 3 massive massive JJ cord-022526-j9kg00qf 500 4 flux flux NN cord-022526-j9kg00qf 500 5 of of IN cord-022526-j9kg00qf 500 6 neutrophils neutrophil NNS cord-022526-j9kg00qf 500 7 through through IN cord-022526-j9kg00qf 500 8 the the DT cord-022526-j9kg00qf 500 9 endothelium endothelium NN cord-022526-j9kg00qf 500 10 alters alter VBZ cord-022526-j9kg00qf 500 11 endothelial endothelial JJ cord-022526-j9kg00qf 500 12 tight tight JJ cord-022526-j9kg00qf 500 13 junctions junction NNS cord-022526-j9kg00qf 500 14 and and CC cord-022526-j9kg00qf 500 15 injures injure VBZ cord-022526-j9kg00qf 500 16 the the DT cord-022526-j9kg00qf 500 17 basement basement NN cord-022526-j9kg00qf 500 18 membrane membrane NN cord-022526-j9kg00qf 500 19 , , , cord-022526-j9kg00qf 500 20 resulting result VBG cord-022526-j9kg00qf 500 21 in in IN cord-022526-j9kg00qf 500 22 increased increase VBN cord-022526-j9kg00qf 500 23 endothelial endothelial JJ cord-022526-j9kg00qf 500 24 permeability permeability NN cord-022526-j9kg00qf 500 25 to to IN cord-022526-j9kg00qf 500 26 molecules molecule NNS cord-022526-j9kg00qf 500 27 as as RB cord-022526-j9kg00qf 500 28 large large JJ cord-022526-j9kg00qf 500 29 as as IN cord-022526-j9kg00qf 500 30 plasma plasma NN cord-022526-j9kg00qf 500 31 proteins protein NNS cord-022526-j9kg00qf 500 32 and and CC cord-022526-j9kg00qf 500 33 even even RB cord-022526-j9kg00qf 500 34 endothelial endothelial JJ cord-022526-j9kg00qf 500 35 cell cell NN cord-022526-j9kg00qf 500 36 detachment detachment NN cord-022526-j9kg00qf 500 37 from from IN cord-022526-j9kg00qf 500 38 the the DT cord-022526-j9kg00qf 500 39 basement basement NN cord-022526-j9kg00qf 500 40 membrane membrane NN cord-022526-j9kg00qf 500 41 . . . cord-022526-j9kg00qf 501 1 17 17 CD cord-022526-j9kg00qf 501 2 , , , cord-022526-j9kg00qf 501 3 18 18 CD cord-022526-j9kg00qf 501 4 Nonintegrin Nonintegrin NNP cord-022526-j9kg00qf 501 5 molecules molecule NNS cord-022526-j9kg00qf 501 6 such such JJ cord-022526-j9kg00qf 501 7 as as IN cord-022526-j9kg00qf 501 8 platelet platelet NN cord-022526-j9kg00qf 501 9 / / SYM cord-022526-j9kg00qf 501 10 endothelial endothelial JJ cord-022526-j9kg00qf 501 11 cell cell NN cord-022526-j9kg00qf 501 12 adhesion adhesion NN cord-022526-j9kg00qf 501 13 molecules molecule NNS cord-022526-j9kg00qf 501 14 ( ( -LRB- cord-022526-j9kg00qf 501 15 PECAMs pecam NNS cord-022526-j9kg00qf 501 16 ) ) -RRB- cord-022526-j9kg00qf 501 17 also also RB cord-022526-j9kg00qf 501 18 are be VBP cord-022526-j9kg00qf 501 19 involved involve VBN cord-022526-j9kg00qf 501 20 in in IN cord-022526-j9kg00qf 501 21 transendothelial transendothelial JJ cord-022526-j9kg00qf 501 22 migration migration NN cord-022526-j9kg00qf 501 23 of of IN cord-022526-j9kg00qf 501 24 neutrophils neutrophil NNS cord-022526-j9kg00qf 501 25 . . . cord-022526-j9kg00qf 502 1 28 28 CD cord-022526-j9kg00qf 503 1 Homotypic Homotypic NNP cord-022526-j9kg00qf 503 2 binding binding NN cord-022526-j9kg00qf 503 3 of of IN cord-022526-j9kg00qf 503 4 PECAMs pecam NNS cord-022526-j9kg00qf 503 5 on on IN cord-022526-j9kg00qf 503 6 adjacent adjacent JJ cord-022526-j9kg00qf 503 7 endothelial endothelial JJ cord-022526-j9kg00qf 503 8 cells cell NNS cord-022526-j9kg00qf 503 9 form form VBP cord-022526-j9kg00qf 503 10 part part NN cord-022526-j9kg00qf 503 11 of of IN cord-022526-j9kg00qf 503 12 the the DT cord-022526-j9kg00qf 503 13 intercellular intercellular JJ cord-022526-j9kg00qf 503 14 junction junction NN cord-022526-j9kg00qf 503 15 . . . cord-022526-j9kg00qf 504 1 Neutrophils neutrophil NNS cord-022526-j9kg00qf 504 2 express express VBP cord-022526-j9kg00qf 504 3 an an DT cord-022526-j9kg00qf 504 4 integrin integrin NN cord-022526-j9kg00qf 504 5 of of IN cord-022526-j9kg00qf 504 6 the the DT cord-022526-j9kg00qf 504 7 β β NN cord-022526-j9kg00qf 504 8 3 3 CD cord-022526-j9kg00qf 504 9 family family NN cord-022526-j9kg00qf 504 10 that that WDT cord-022526-j9kg00qf 504 11 can can MD cord-022526-j9kg00qf 504 12 bind bind VB cord-022526-j9kg00qf 504 13 PECAM PECAM NNP cord-022526-j9kg00qf 504 14 , , , cord-022526-j9kg00qf 504 15 and and CC cord-022526-j9kg00qf 504 16 via via IN cord-022526-j9kg00qf 504 17 sequential sequential JJ cord-022526-j9kg00qf 504 18 binding binding NN cord-022526-j9kg00qf 504 19 of of IN cord-022526-j9kg00qf 504 20 β β NN cord-022526-j9kg00qf 504 21 3 3 CD cord-022526-j9kg00qf 504 22 integrins integrin NNS cord-022526-j9kg00qf 504 23 to to IN cord-022526-j9kg00qf 504 24 PECAM PECAM NNP cord-022526-j9kg00qf 504 25 , , , cord-022526-j9kg00qf 504 26 the the DT cord-022526-j9kg00qf 504 27 neutrophil neutrophil NN cord-022526-j9kg00qf 504 28 can can MD cord-022526-j9kg00qf 504 29 , , , cord-022526-j9kg00qf 504 30 and and CC cord-022526-j9kg00qf 504 31 other other JJ cord-022526-j9kg00qf 504 32 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 504 33 mediators mediator NNS cord-022526-j9kg00qf 504 34 . . . cord-022526-j9kg00qf 505 1 Endothelial endothelial JJ cord-022526-j9kg00qf 505 2 cells cell NNS cord-022526-j9kg00qf 505 3 stimulated stimulate VBN cord-022526-j9kg00qf 505 4 by by IN cord-022526-j9kg00qf 505 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 505 6 mediators mediator NNS cord-022526-j9kg00qf 505 7 produce produce VBP cord-022526-j9kg00qf 505 8 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 505 9 ( ( -LRB- cord-022526-j9kg00qf 505 10 such such JJ cord-022526-j9kg00qf 505 11 as as IN cord-022526-j9kg00qf 505 12 IL-8 IL-8 NNP cord-022526-j9kg00qf 505 13 ) ) -RRB- cord-022526-j9kg00qf 505 14 and and CC cord-022526-j9kg00qf 505 15 display display NN cord-022526-j9kg00qf 505 16 adhesion adhesion NN cord-022526-j9kg00qf 505 17 molecules molecule NNS cord-022526-j9kg00qf 505 18 that that WDT cord-022526-j9kg00qf 505 19 promote promote VBP cord-022526-j9kg00qf 505 20 neutrophil neutrophil NN cord-022526-j9kg00qf 505 21 emigration emigration NN cord-022526-j9kg00qf 505 22 . . . cord-022526-j9kg00qf 506 1 The the DT cord-022526-j9kg00qf 506 2 three three CD cord-022526-j9kg00qf 506 3 steps step NNS cord-022526-j9kg00qf 506 4 of of IN cord-022526-j9kg00qf 506 5 neutrophil neutrophil NN cord-022526-j9kg00qf 506 6 ( ( -LRB- cord-022526-j9kg00qf 506 7 polymorphonuclear polymorphonuclear NNP cord-022526-j9kg00qf 506 8 [ [ -LRB- cord-022526-j9kg00qf 506 9 PMN PMN NNP cord-022526-j9kg00qf 506 10 ] ] -RRB- cord-022526-j9kg00qf 506 11 ) ) -RRB- cord-022526-j9kg00qf 507 1 emigrationcapture emigrationcapture NNP cord-022526-j9kg00qf 507 2 / / SYM cord-022526-j9kg00qf 507 3 rolling rolling NN cord-022526-j9kg00qf 507 4 ( ( -LRB- cord-022526-j9kg00qf 507 5 mediated mediate VBN cord-022526-j9kg00qf 507 6 by by IN cord-022526-j9kg00qf 507 7 selectins selectin NNS cord-022526-j9kg00qf 507 8 ) ) -RRB- cord-022526-j9kg00qf 507 9 , , , cord-022526-j9kg00qf 507 10 adhesion adhesion NN cord-022526-j9kg00qf 507 11 ( ( -LRB- cord-022526-j9kg00qf 507 12 mediated mediate VBN cord-022526-j9kg00qf 507 13 by by IN cord-022526-j9kg00qf 507 14 β β NN cord-022526-j9kg00qf 507 15 2 2 CD cord-022526-j9kg00qf 507 16 integrins integrin NNS cord-022526-j9kg00qf 507 17 ) ) -RRB- cord-022526-j9kg00qf 507 18 , , , cord-022526-j9kg00qf 507 19 and and CC cord-022526-j9kg00qf 507 20 transendothelial transendothelial JJ cord-022526-j9kg00qf 507 21 migration migration NN cord-022526-j9kg00qf 507 22 ( ( -LRB- cord-022526-j9kg00qf 507 23 mediated mediate VBN cord-022526-j9kg00qf 507 24 by by IN cord-022526-j9kg00qf 507 25 integrins integrin NNS cord-022526-j9kg00qf 507 26 and and CC cord-022526-j9kg00qf 507 27 platelet platelet NN cord-022526-j9kg00qf 507 28 / / SYM cord-022526-j9kg00qf 507 29 endothelial endothelial JJ cord-022526-j9kg00qf 507 30 cellular cellular JJ cord-022526-j9kg00qf 507 31 adhesion adhesion NN cord-022526-j9kg00qf 507 32 molecule molecule NN cord-022526-j9kg00qf 507 33 [ [ -LRB- cord-022526-j9kg00qf 508 1 PECAM])-occur pecam])-occur RB cord-022526-j9kg00qf 508 2 on on IN cord-022526-j9kg00qf 508 3 activated activate VBN cord-022526-j9kg00qf 508 4 endothelium endothelium NN cord-022526-j9kg00qf 508 5 . . . cord-022526-j9kg00qf 509 1 Chemoattractant chemoattractant JJ cord-022526-j9kg00qf 509 2 molecules molecule NNS cord-022526-j9kg00qf 509 3 , , , cord-022526-j9kg00qf 509 4 such such JJ cord-022526-j9kg00qf 509 5 as as IN cord-022526-j9kg00qf 509 6 IL-8 il-8 NN cord-022526-j9kg00qf 509 7 trigger trigger NN cord-022526-j9kg00qf 509 8 neutrophil neutrophil NN cord-022526-j9kg00qf 509 9 emigration emigration NN cord-022526-j9kg00qf 509 10 . . . cord-022526-j9kg00qf 510 1 In in IN cord-022526-j9kg00qf 510 2 inflamed inflamed JJ cord-022526-j9kg00qf 510 3 tissues tissue NNS cord-022526-j9kg00qf 510 4 , , , cord-022526-j9kg00qf 510 5 cytokines cytokine NNS cord-022526-j9kg00qf 510 6 ( ( -LRB- cord-022526-j9kg00qf 510 7 IL-1β IL-1β NNP cord-022526-j9kg00qf 510 8 and and CC cord-022526-j9kg00qf 510 9 TNF TNF NNP cord-022526-j9kg00qf 510 10 - - HYPH cord-022526-j9kg00qf 510 11 α α NNP cord-022526-j9kg00qf 510 12 ) ) -RRB- cord-022526-j9kg00qf 510 13 and and CC cord-022526-j9kg00qf 510 14 a a DT cord-022526-j9kg00qf 510 15 variety variety NN cord-022526-j9kg00qf 510 16 of of IN cord-022526-j9kg00qf 510 17 other other JJ cord-022526-j9kg00qf 510 18 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 510 19 mediators mediator NNS cord-022526-j9kg00qf 510 20 stimulate stimulate VBP cord-022526-j9kg00qf 510 21 the the DT cord-022526-j9kg00qf 510 22 neutrophil neutrophil NN cord-022526-j9kg00qf 510 23 oxidase oxidase NN cord-022526-j9kg00qf 510 24 complex complex NN cord-022526-j9kg00qf 510 25 to to TO cord-022526-j9kg00qf 510 26 produce produce VB cord-022526-j9kg00qf 510 27 reactive reactive JJ cord-022526-j9kg00qf 510 28 oxygen oxygen NN cord-022526-j9kg00qf 510 29 intermediates intermediate NNS cord-022526-j9kg00qf 510 30 ( ( -LRB- cord-022526-j9kg00qf 510 31 ROIs roi NNS cord-022526-j9kg00qf 510 32 ; ; : cord-022526-j9kg00qf 510 33 O o UH cord-022526-j9kg00qf 510 34 2 2 CD cord-022526-j9kg00qf 510 35 and and CC cord-022526-j9kg00qf 510 36 H h NN cord-022526-j9kg00qf 510 37 2 2 CD cord-022526-j9kg00qf 510 38 O o NN cord-022526-j9kg00qf 510 39 2 2 CD cord-022526-j9kg00qf 510 40 and and CC cord-022526-j9kg00qf 510 41 their -PRON- PRP$ cord-022526-j9kg00qf 510 42 derivatives derivative NNS cord-022526-j9kg00qf 510 43 ) ) -RRB- cord-022526-j9kg00qf 510 44 . . . cord-022526-j9kg00qf 511 1 Activated Activated NNP cord-022526-j9kg00qf 511 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 511 3 degranulate degranulate NNP cord-022526-j9kg00qf 511 4 to to TO cord-022526-j9kg00qf 511 5 release release VB cord-022526-j9kg00qf 511 6 proteases protease NNS cord-022526-j9kg00qf 511 7 and and CC cord-022526-j9kg00qf 511 8 other other JJ cord-022526-j9kg00qf 511 9 hydrolases hydrolase NNS cord-022526-j9kg00qf 511 10 , , , cord-022526-j9kg00qf 511 11 cationic cationic JJ cord-022526-j9kg00qf 511 12 peptides peptide NNS cord-022526-j9kg00qf 511 13 ( ( -LRB- cord-022526-j9kg00qf 511 14 defensins defensins NNP cord-022526-j9kg00qf 511 15 ) ) -RRB- cord-022526-j9kg00qf 511 16 , , , cord-022526-j9kg00qf 511 17 myeloperoxidase myeloperoxidase NNP cord-022526-j9kg00qf 511 18 , , , cord-022526-j9kg00qf 511 19 and and CC cord-022526-j9kg00qf 511 20 other other JJ cord-022526-j9kg00qf 511 21 products product NNS cord-022526-j9kg00qf 511 22 into into IN cord-022526-j9kg00qf 511 23 the the DT cord-022526-j9kg00qf 511 24 tissue tissue NN cord-022526-j9kg00qf 511 25 . . . cord-022526-j9kg00qf 512 1 Activated activate VBN cord-022526-j9kg00qf 512 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 512 3 synthesize synthesize VBP cord-022526-j9kg00qf 512 4 a a DT cord-022526-j9kg00qf 512 5 variety variety NN cord-022526-j9kg00qf 512 6 of of IN cord-022526-j9kg00qf 512 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 512 8 mediators mediator NNS cord-022526-j9kg00qf 512 9 , , , cord-022526-j9kg00qf 512 10 including include VBG cord-022526-j9kg00qf 512 11 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 512 12 ( ( -LRB- cord-022526-j9kg00qf 512 13 PGE PGE NNP cord-022526-j9kg00qf 512 14 2 2 CD cord-022526-j9kg00qf 512 15 ) ) -RRB- cord-022526-j9kg00qf 512 16 that that WDT cord-022526-j9kg00qf 512 17 modulate modulate VBP cord-022526-j9kg00qf 512 18 the the DT cord-022526-j9kg00qf 512 19 inflammatory inflammatory JJ cord-022526-j9kg00qf 512 20 response response NN cord-022526-j9kg00qf 512 21 . . . cord-022526-j9kg00qf 513 1 The the DT cord-022526-j9kg00qf 513 2 products product NNS cord-022526-j9kg00qf 513 3 of of IN cord-022526-j9kg00qf 513 4 activated activate VBN cord-022526-j9kg00qf 513 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 513 6 ( ( -LRB- cord-022526-j9kg00qf 513 7 ROIs roi NNS cord-022526-j9kg00qf 513 8 , , , cord-022526-j9kg00qf 513 9 proteases protease NNS cord-022526-j9kg00qf 513 10 , , , cord-022526-j9kg00qf 513 11 and and CC cord-022526-j9kg00qf 513 12 mediators mediator NNS cord-022526-j9kg00qf 513 13 ) ) -RRB- cord-022526-j9kg00qf 513 14 stimulate stimulate VBP cord-022526-j9kg00qf 513 15 epithelial epithelial JJ cord-022526-j9kg00qf 513 16 secretion secretion NN cord-022526-j9kg00qf 513 17 and and CC cord-022526-j9kg00qf 513 18 alter alter VB cord-022526-j9kg00qf 513 19 tight tight JJ cord-022526-j9kg00qf 513 20 junction junction NN cord-022526-j9kg00qf 513 21 permeability permeability NN cord-022526-j9kg00qf 513 22 , , , cord-022526-j9kg00qf 513 23 promoting promote VBG cord-022526-j9kg00qf 513 24 diarrhea diarrhea NN cord-022526-j9kg00qf 513 25 . . . cord-022526-j9kg00qf 514 1 Neutrophils neutrophils NN cord-022526-j9kg00qf 514 2 eventually eventually RB cord-022526-j9kg00qf 514 3 migrate migrate VBP cord-022526-j9kg00qf 514 4 across across IN cord-022526-j9kg00qf 514 5 the the DT cord-022526-j9kg00qf 514 6 infected infected JJ cord-022526-j9kg00qf 514 7 epithelium epithelium NN cord-022526-j9kg00qf 514 8 by by IN cord-022526-j9kg00qf 514 9 a a DT cord-022526-j9kg00qf 514 10 mechanism mechanism NN cord-022526-j9kg00qf 514 11 that that WDT cord-022526-j9kg00qf 514 12 involves involve VBZ cord-022526-j9kg00qf 514 13 integrins integrin NNS cord-022526-j9kg00qf 514 14 , , , cord-022526-j9kg00qf 514 15 disrupting disrupt VBG cord-022526-j9kg00qf 514 16 tight tight JJ cord-022526-j9kg00qf 514 17 junction junction NN cord-022526-j9kg00qf 514 18 integrity integrity NN cord-022526-j9kg00qf 514 19 and and CC cord-022526-j9kg00qf 514 20 increasing increase VBG cord-022526-j9kg00qf 514 21 permeability permeability NN cord-022526-j9kg00qf 514 22 to to IN cord-022526-j9kg00qf 514 23 bacterial bacterial JJ cord-022526-j9kg00qf 514 24 products product NNS cord-022526-j9kg00qf 514 25 , , , cord-022526-j9kg00qf 514 26 thus thus RB cord-022526-j9kg00qf 514 27 exacerbating exacerbate VBG cord-022526-j9kg00qf 514 28 the the DT cord-022526-j9kg00qf 514 29 inflammatory inflammatory JJ cord-022526-j9kg00qf 514 30 response response NN cord-022526-j9kg00qf 514 31 . . . cord-022526-j9kg00qf 515 1 " " `` cord-022526-j9kg00qf 515 2 unzip unzip VB cord-022526-j9kg00qf 515 3 " " '' cord-022526-j9kg00qf 515 4 the the DT cord-022526-j9kg00qf 515 5 intercellular intercellular JJ cord-022526-j9kg00qf 515 6 junction junction NN cord-022526-j9kg00qf 515 7 and and CC cord-022526-j9kg00qf 515 8 migrate migrate VB cord-022526-j9kg00qf 515 9 through through RB cord-022526-j9kg00qf 515 10 , , , cord-022526-j9kg00qf 515 11 closing close VBG cord-022526-j9kg00qf 515 12 it -PRON- PRP cord-022526-j9kg00qf 515 13 behind behind IN cord-022526-j9kg00qf 515 14 itself -PRON- PRP cord-022526-j9kg00qf 515 15 . . . cord-022526-j9kg00qf 516 1 A a DT cord-022526-j9kg00qf 516 2 key key JJ cord-022526-j9kg00qf 516 3 feature feature NN cord-022526-j9kg00qf 516 4 of of IN cord-022526-j9kg00qf 516 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 516 6 and and CC cord-022526-j9kg00qf 516 7 other other JJ cord-022526-j9kg00qf 516 8 leukocytes leukocyte NNS cord-022526-j9kg00qf 516 9 is be VBZ cord-022526-j9kg00qf 516 10 the the DT cord-022526-j9kg00qf 516 11 requirement requirement NN cord-022526-j9kg00qf 516 12 for for IN cord-022526-j9kg00qf 516 13 integrin integrin NN cord-022526-j9kg00qf 516 14 - - HYPH cord-022526-j9kg00qf 516 15 mediated mediate VBN cord-022526-j9kg00qf 516 16 adhesion adhesion NN cord-022526-j9kg00qf 516 17 to to IN cord-022526-j9kg00qf 516 18 extracellular extracellular JJ cord-022526-j9kg00qf 516 19 matrix matrix NN cord-022526-j9kg00qf 516 20 proteins protein NNS cord-022526-j9kg00qf 516 21 ( ( -LRB- cord-022526-j9kg00qf 516 22 ECMs ECMs NNP cord-022526-j9kg00qf 516 23 ) ) -RRB- cord-022526-j9kg00qf 516 24 or or CC cord-022526-j9kg00qf 516 25 other other JJ cord-022526-j9kg00qf 516 26 cells cell NNS cord-022526-j9kg00qf 516 27 to to TO cord-022526-j9kg00qf 516 28 achieve achieve VB cord-022526-j9kg00qf 516 29 an an DT cord-022526-j9kg00qf 516 30 optimal optimal JJ cord-022526-j9kg00qf 516 31 effector effector NN cord-022526-j9kg00qf 516 32 phenotype phenotype NN cord-022526-j9kg00qf 516 33 . . . cord-022526-j9kg00qf 517 1 34 34 CD cord-022526-j9kg00qf 517 2 Critical critical JJ cord-022526-j9kg00qf 517 3 components component NNS cord-022526-j9kg00qf 517 4 of of IN cord-022526-j9kg00qf 517 5 the the DT cord-022526-j9kg00qf 517 6 ECMs ECMs NNP cord-022526-j9kg00qf 517 7 in in IN cord-022526-j9kg00qf 517 8 inflamed inflamed JJ cord-022526-j9kg00qf 517 9 tissues tissue NNS cord-022526-j9kg00qf 517 10 include include VBP cord-022526-j9kg00qf 517 11 fibronectin fibronectin NN cord-022526-j9kg00qf 517 12 , , , cord-022526-j9kg00qf 517 13 fibrinogen fibrinogen NN cord-022526-j9kg00qf 517 14 , , , cord-022526-j9kg00qf 517 15 and and CC cord-022526-j9kg00qf 517 16 vitronectin vitronectin NNP cord-022526-j9kg00qf 517 17 , , , cord-022526-j9kg00qf 517 18 deposited deposit VBN cord-022526-j9kg00qf 517 19 in in IN cord-022526-j9kg00qf 517 20 tissues tissue NNS cord-022526-j9kg00qf 517 21 as as IN cord-022526-j9kg00qf 517 22 a a DT cord-022526-j9kg00qf 517 23 result result NN cord-022526-j9kg00qf 517 24 of of IN cord-022526-j9kg00qf 517 25 plasma plasma NN cord-022526-j9kg00qf 517 26 leakage leakage NN cord-022526-j9kg00qf 517 27 and and CC cord-022526-j9kg00qf 517 28 by by IN cord-022526-j9kg00qf 517 29 synthesis synthesis NN cord-022526-j9kg00qf 517 30 of of IN cord-022526-j9kg00qf 517 31 new new JJ cord-022526-j9kg00qf 517 32 proteins protein NNS cord-022526-j9kg00qf 517 33 by by IN cord-022526-j9kg00qf 517 34 stromal stromal JJ cord-022526-j9kg00qf 517 35 cells cell NNS cord-022526-j9kg00qf 517 36 and and CC cord-022526-j9kg00qf 517 37 resident resident JJ cord-022526-j9kg00qf 517 38 macrophages macrophage NNS cord-022526-j9kg00qf 517 39 in in IN cord-022526-j9kg00qf 517 40 response response NN cord-022526-j9kg00qf 517 41 to to IN cord-022526-j9kg00qf 517 42 inflammatory inflammatory JJ cord-022526-j9kg00qf 517 43 mediator mediator NN cord-022526-j9kg00qf 517 44 activation activation NN cord-022526-j9kg00qf 517 45 . . . cord-022526-j9kg00qf 518 1 The the DT cord-022526-j9kg00qf 518 2 changing change VBG cord-022526-j9kg00qf 518 3 composition composition NN cord-022526-j9kg00qf 518 4 of of IN cord-022526-j9kg00qf 518 5 the the DT cord-022526-j9kg00qf 518 6 matrix matrix NN cord-022526-j9kg00qf 518 7 proteins protein NNS cord-022526-j9kg00qf 518 8 deposited deposit VBN cord-022526-j9kg00qf 518 9 in in IN cord-022526-j9kg00qf 518 10 tissues tissue NNS cord-022526-j9kg00qf 518 11 during during IN cord-022526-j9kg00qf 518 12 inflammation inflammation NN cord-022526-j9kg00qf 518 13 serves serve VBZ cord-022526-j9kg00qf 518 14 as as IN cord-022526-j9kg00qf 518 15 a a DT cord-022526-j9kg00qf 518 16 clue clue NN cord-022526-j9kg00qf 518 17 as as IN cord-022526-j9kg00qf 518 18 to to IN cord-022526-j9kg00qf 518 19 the the DT cord-022526-j9kg00qf 518 20 nature nature NN cord-022526-j9kg00qf 518 21 of of IN cord-022526-j9kg00qf 518 22 the the DT cord-022526-j9kg00qf 518 23 tissue tissue NN cord-022526-j9kg00qf 518 24 environment environment NN cord-022526-j9kg00qf 518 25 for for IN cord-022526-j9kg00qf 518 26 recruited recruit VBN cord-022526-j9kg00qf 518 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 518 28 cells cell NNS cord-022526-j9kg00qf 518 29 as as IN cord-022526-j9kg00qf 518 30 they -PRON- PRP cord-022526-j9kg00qf 518 31 become become VBP cord-022526-j9kg00qf 518 32 activated activate VBN cord-022526-j9kg00qf 518 33 . . . cord-022526-j9kg00qf 519 1 Individual individual JJ cord-022526-j9kg00qf 519 2 gene gene NN cord-022526-j9kg00qf 519 3 expression expression NN cord-022526-j9kg00qf 519 4 studies study NNS cord-022526-j9kg00qf 519 5 have have VBP cord-022526-j9kg00qf 519 6 demonstrated demonstrate VBN cord-022526-j9kg00qf 519 7 that that DT cord-022526-j9kg00qf 519 8 adhesion adhesion NN cord-022526-j9kg00qf 519 9 to to IN cord-022526-j9kg00qf 519 10 matrix matrix NN cord-022526-j9kg00qf 519 11 proteins protein NNS cord-022526-j9kg00qf 519 12 induces induce VBZ cord-022526-j9kg00qf 519 13 the the DT cord-022526-j9kg00qf 519 14 expression expression NN cord-022526-j9kg00qf 519 15 of of IN cord-022526-j9kg00qf 519 16 cytokines cytokine NNS cord-022526-j9kg00qf 519 17 and and CC cord-022526-j9kg00qf 519 18 chemokines chemokine NNS cord-022526-j9kg00qf 519 19 and and CC cord-022526-j9kg00qf 519 20 their -PRON- PRP$ cord-022526-j9kg00qf 519 21 receptors receptor NNS cord-022526-j9kg00qf 519 22 , , , cord-022526-j9kg00qf 519 23 arachidonic arachidonic JJ cord-022526-j9kg00qf 519 24 acid acid NN cord-022526-j9kg00qf 519 25 - - HYPH cord-022526-j9kg00qf 519 26 derived derive VBN cord-022526-j9kg00qf 519 27 lipid lipid NN cord-022526-j9kg00qf 519 28 mediator mediator NN cord-022526-j9kg00qf 519 29 synthases synthase NNS cord-022526-j9kg00qf 519 30 , , , cord-022526-j9kg00qf 519 31 metalloproteinases metalloproteinase NNS cord-022526-j9kg00qf 519 32 , , , cord-022526-j9kg00qf 519 33 growth growth NN cord-022526-j9kg00qf 519 34 factors factor NNS cord-022526-j9kg00qf 519 35 , , , cord-022526-j9kg00qf 519 36 transcription transcription NN cord-022526-j9kg00qf 519 37 factors factor NNS cord-022526-j9kg00qf 519 38 , , , cord-022526-j9kg00qf 519 39 and and CC cord-022526-j9kg00qf 519 40 other other JJ cord-022526-j9kg00qf 519 41 genes gene NNS cord-022526-j9kg00qf 519 42 that that WDT cord-022526-j9kg00qf 519 43 influence influence VBP cord-022526-j9kg00qf 519 44 the the DT cord-022526-j9kg00qf 519 45 differentiation differentiation NN cord-022526-j9kg00qf 519 46 and and CC cord-022526-j9kg00qf 519 47 activation activation NN cord-022526-j9kg00qf 519 48 of of IN cord-022526-j9kg00qf 519 49 inflammatory inflammatory JJ cord-022526-j9kg00qf 519 50 cells cell NNS cord-022526-j9kg00qf 519 51 . . . cord-022526-j9kg00qf 520 1 35 35 CD cord-022526-j9kg00qf 520 2 ROI ROI NNP cord-022526-j9kg00qf 520 3 production production NN cord-022526-j9kg00qf 520 4 , , , cord-022526-j9kg00qf 520 5 phagocytosis phagocytosis NN cord-022526-j9kg00qf 520 6 , , , cord-022526-j9kg00qf 520 7 degranulation degranulation NN cord-022526-j9kg00qf 520 8 , , , cord-022526-j9kg00qf 520 9 and and CC cord-022526-j9kg00qf 520 10 other other JJ cord-022526-j9kg00qf 520 11 effector effector NN cord-022526-j9kg00qf 520 12 functions function NNS cord-022526-j9kg00qf 520 13 stimulated stimulate VBN cord-022526-j9kg00qf 520 14 by by IN cord-022526-j9kg00qf 520 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 520 16 mediators mediator NNS cord-022526-j9kg00qf 520 17 and and CC cord-022526-j9kg00qf 520 18 bacterial bacterial JJ cord-022526-j9kg00qf 520 19 products product NNS cord-022526-j9kg00qf 520 20 are be VBP cord-022526-j9kg00qf 520 21 optimal optimal JJ cord-022526-j9kg00qf 520 22 only only RB cord-022526-j9kg00qf 520 23 when when WRB cord-022526-j9kg00qf 520 24 neutrophils neutrophil NNS cord-022526-j9kg00qf 520 25 adhere adhere VBP cord-022526-j9kg00qf 520 26 to to IN cord-022526-j9kg00qf 520 27 the the DT cord-022526-j9kg00qf 520 28 ECMs ECMs NNP cord-022526-j9kg00qf 520 29 . . . cord-022526-j9kg00qf 521 1 34 34 CD cord-022526-j9kg00qf 521 2 Adhesion adhesion NN cord-022526-j9kg00qf 521 3 to to IN cord-022526-j9kg00qf 521 4 distinct distinct JJ cord-022526-j9kg00qf 521 5 ECM ECM NNP cord-022526-j9kg00qf 521 6 proteins protein NNS cord-022526-j9kg00qf 521 7 selectively selectively RB cord-022526-j9kg00qf 521 8 activates activate VBZ cord-022526-j9kg00qf 521 9 signaling signal VBG cord-022526-j9kg00qf 521 10 pathways pathway NNS cord-022526-j9kg00qf 521 11 and and CC cord-022526-j9kg00qf 521 12 gene gene NN cord-022526-j9kg00qf 521 13 expression expression NN cord-022526-j9kg00qf 521 14 of of IN cord-022526-j9kg00qf 521 15 neutrophils neutrophil NNS cord-022526-j9kg00qf 521 16 , , , cord-022526-j9kg00qf 521 17 monocytes monocyte NNS cord-022526-j9kg00qf 521 18 , , , cord-022526-j9kg00qf 521 19 and and CC cord-022526-j9kg00qf 521 20 other other JJ cord-022526-j9kg00qf 521 21 leukocytes leukocyte NNS cord-022526-j9kg00qf 521 22 with with IN cord-022526-j9kg00qf 521 23 differing differ VBG cord-022526-j9kg00qf 521 24 abilities ability NNS cord-022526-j9kg00qf 521 25 to to TO cord-022526-j9kg00qf 521 26 promote promote VB cord-022526-j9kg00qf 521 27 certain certain JJ cord-022526-j9kg00qf 521 28 functions function NNS cord-022526-j9kg00qf 521 29 such such JJ cord-022526-j9kg00qf 521 30 that that IN cord-022526-j9kg00qf 521 31 the the DT cord-022526-j9kg00qf 521 32 composition composition NN cord-022526-j9kg00qf 521 33 of of IN cord-022526-j9kg00qf 521 34 ECMs ECMs NNP cord-022526-j9kg00qf 521 35 in in IN cord-022526-j9kg00qf 521 36 many many JJ cord-022526-j9kg00qf 521 37 ways way NNS cord-022526-j9kg00qf 521 38 controls control VBZ cord-022526-j9kg00qf 521 39 the the DT cord-022526-j9kg00qf 521 40 development development NN cord-022526-j9kg00qf 521 41 of of IN cord-022526-j9kg00qf 521 42 the the DT cord-022526-j9kg00qf 521 43 ultimate ultimate JJ cord-022526-j9kg00qf 521 44 effector effector NN cord-022526-j9kg00qf 521 45 phenotype phenotype NN cord-022526-j9kg00qf 521 46 . . . cord-022526-j9kg00qf 522 1 Thus thus RB cord-022526-j9kg00qf 522 2 integrin integrin NN cord-022526-j9kg00qf 522 3 - - HYPH cord-022526-j9kg00qf 522 4 mediated mediate VBN cord-022526-j9kg00qf 522 5 adhesion adhesion NN cord-022526-j9kg00qf 522 6 provides provide VBZ cord-022526-j9kg00qf 522 7 a a DT cord-022526-j9kg00qf 522 8 mechanism mechanism NN cord-022526-j9kg00qf 522 9 by by IN cord-022526-j9kg00qf 522 10 which which WDT cord-022526-j9kg00qf 522 11 neutrophils neutrophil NNS cord-022526-j9kg00qf 522 12 and and CC cord-022526-j9kg00qf 522 13 other other JJ cord-022526-j9kg00qf 522 14 leukocytes leukocyte NNS cord-022526-j9kg00qf 522 15 can can MD cord-022526-j9kg00qf 522 16 sense sense VB cord-022526-j9kg00qf 522 17 the the DT cord-022526-j9kg00qf 522 18 complex complex JJ cord-022526-j9kg00qf 522 19 tissue tissue NN cord-022526-j9kg00qf 522 20 environment environment NN cord-022526-j9kg00qf 522 21 and and CC cord-022526-j9kg00qf 522 22 respond respond VB cord-022526-j9kg00qf 522 23 appropriately appropriately RB cord-022526-j9kg00qf 522 24 . . . cord-022526-j9kg00qf 523 1 Of of IN cord-022526-j9kg00qf 523 2 the the DT cord-022526-j9kg00qf 523 3 activators activator NNS cord-022526-j9kg00qf 523 4 of of IN cord-022526-j9kg00qf 523 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 523 6 at at IN cord-022526-j9kg00qf 523 7 sites site NNS cord-022526-j9kg00qf 523 8 of of IN cord-022526-j9kg00qf 523 9 inflammation inflammation NN cord-022526-j9kg00qf 523 10 , , , cord-022526-j9kg00qf 523 11 complement complement NN cord-022526-j9kg00qf 523 12 ( ( -LRB- cord-022526-j9kg00qf 523 13 C3-opsonized c3-opsonize VBN cord-022526-j9kg00qf 523 14 particles particle NNS cord-022526-j9kg00qf 523 15 ) ) -RRB- cord-022526-j9kg00qf 523 16 , , , cord-022526-j9kg00qf 523 17 cytokines cytokine NNS cord-022526-j9kg00qf 523 18 ( ( -LRB- cord-022526-j9kg00qf 523 19 TNF TNF NNP cord-022526-j9kg00qf 523 20 - - HYPH cord-022526-j9kg00qf 523 21 α α NNP cord-022526-j9kg00qf 523 22 and and CC cord-022526-j9kg00qf 523 23 IL-1β IL-1β NNP cord-022526-j9kg00qf 523 24 ) ) -RRB- cord-022526-j9kg00qf 523 25 , , , cord-022526-j9kg00qf 523 26 platelet platelet NN cord-022526-j9kg00qf 523 27 - - HYPH cord-022526-j9kg00qf 523 28 activating activate VBG cord-022526-j9kg00qf 523 29 factor factor NN cord-022526-j9kg00qf 523 30 , , , cord-022526-j9kg00qf 523 31 immune immune JJ cord-022526-j9kg00qf 523 32 complexes complex NNS cord-022526-j9kg00qf 523 33 , , , cord-022526-j9kg00qf 523 34 and and CC cord-022526-j9kg00qf 523 35 bacterial bacterial JJ cord-022526-j9kg00qf 523 36 products product NNS cord-022526-j9kg00qf 523 37 are be VBP cord-022526-j9kg00qf 523 38 among among IN cord-022526-j9kg00qf 523 39 the the DT cord-022526-j9kg00qf 523 40 most most RBS cord-022526-j9kg00qf 523 41 potent potent JJ cord-022526-j9kg00qf 523 42 stimuli stimulus NNS cord-022526-j9kg00qf 523 43 . . . cord-022526-j9kg00qf 524 1 Other other JJ cord-022526-j9kg00qf 524 2 mediators mediator NNS cord-022526-j9kg00qf 524 3 produced produce VBD cord-022526-j9kg00qf 524 4 during during IN cord-022526-j9kg00qf 524 5 inflammation inflammation NN cord-022526-j9kg00qf 524 6 may may MD cord-022526-j9kg00qf 524 7 modify modify VB cord-022526-j9kg00qf 524 8 neutrophil neutrophil NN cord-022526-j9kg00qf 524 9 activity activity NN cord-022526-j9kg00qf 524 10 , , , cord-022526-j9kg00qf 524 11 particularly particularly RB cord-022526-j9kg00qf 524 12 formylated formylate VBN cord-022526-j9kg00qf 524 13 bacterial bacterial JJ cord-022526-j9kg00qf 524 14 peptides peptide NNS cord-022526-j9kg00qf 524 15 , , , cord-022526-j9kg00qf 524 16 chemokines chemokine NNS cord-022526-j9kg00qf 524 17 , , , cord-022526-j9kg00qf 524 18 complement complement NN cord-022526-j9kg00qf 524 19 fragments fragment NNS cord-022526-j9kg00qf 524 20 ( ( -LRB- cord-022526-j9kg00qf 524 21 C5a C5a NNS cord-022526-j9kg00qf 524 22 ) ) -RRB- cord-022526-j9kg00qf 524 23 , , , cord-022526-j9kg00qf 524 24 leukotriene leukotriene NN cord-022526-j9kg00qf 524 25 B B NNP cord-022526-j9kg00qf 524 26 4 4 CD cord-022526-j9kg00qf 524 27 , , , cord-022526-j9kg00qf 524 28 and and CC cord-022526-j9kg00qf 524 29 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 524 30 . . . cord-022526-j9kg00qf 525 1 Activated activate VBN cord-022526-j9kg00qf 525 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 525 3 are be VBP cord-022526-j9kg00qf 525 4 highly highly RB cord-022526-j9kg00qf 525 5 phagocytic phagocytic JJ cord-022526-j9kg00qf 525 6 ; ; : cord-022526-j9kg00qf 525 7 produce produce VB cord-022526-j9kg00qf 525 8 large large JJ cord-022526-j9kg00qf 525 9 amounts amount NNS cord-022526-j9kg00qf 525 10 of of IN cord-022526-j9kg00qf 525 11 ROIs roi NNS cord-022526-j9kg00qf 525 12 ; ; , cord-022526-j9kg00qf 525 13 degranulate degranulate NNP cord-022526-j9kg00qf 525 14 to to TO cord-022526-j9kg00qf 525 15 release release VB cord-022526-j9kg00qf 525 16 myeloperoxidase myeloperoxidase NN cord-022526-j9kg00qf 525 17 , , , cord-022526-j9kg00qf 525 18 cationic cationic JJ cord-022526-j9kg00qf 525 19 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 525 20 peptides peptide NNS cord-022526-j9kg00qf 525 21 ( ( -LRB- cord-022526-j9kg00qf 525 22 defensins defensins NNP cord-022526-j9kg00qf 525 23 ) ) -RRB- cord-022526-j9kg00qf 525 24 , , , cord-022526-j9kg00qf 525 25 serine serine NN cord-022526-j9kg00qf 525 26 proteases protease NNS cord-022526-j9kg00qf 525 27 ( ( -LRB- cord-022526-j9kg00qf 525 28 mainly mainly RB cord-022526-j9kg00qf 525 29 elastase elastase NN cord-022526-j9kg00qf 525 30 ) ) -RRB- cord-022526-j9kg00qf 525 31 , , , cord-022526-j9kg00qf 525 32 and and CC cord-022526-j9kg00qf 525 33 metalloproteinases metalloproteinase NNS cord-022526-j9kg00qf 525 34 ; ; : cord-022526-j9kg00qf 525 35 and and CC cord-022526-j9kg00qf 525 36 secrete secrete VB cord-022526-j9kg00qf 525 37 inflammatory inflammatory JJ cord-022526-j9kg00qf 525 38 mediators mediator NNS cord-022526-j9kg00qf 525 39 ( ( -LRB- cord-022526-j9kg00qf 525 40 TNF TNF NNP cord-022526-j9kg00qf 525 41 - - HYPH cord-022526-j9kg00qf 525 42 α α NNP cord-022526-j9kg00qf 525 43 , , , cord-022526-j9kg00qf 525 44 IL-1β il-1β NN cord-022526-j9kg00qf 525 45 , , , cord-022526-j9kg00qf 525 46 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 525 47 , , , cord-022526-j9kg00qf 525 48 leukotrienes leukotriene NNS cord-022526-j9kg00qf 525 49 , , , cord-022526-j9kg00qf 525 50 and and CC cord-022526-j9kg00qf 525 51 others other NNS cord-022526-j9kg00qf 525 52 ) ) -RRB- cord-022526-j9kg00qf 525 53 ( ( -LRB- cord-022526-j9kg00qf 525 54 see see VB cord-022526-j9kg00qf 525 55 Figure Figure NNP cord-022526-j9kg00qf 525 56 13 13 CD cord-022526-j9kg00qf 525 57 .2 .2 CD cord-022526-j9kg00qf 525 58 - - SYM cord-022526-j9kg00qf 525 59 1 1 CD cord-022526-j9kg00qf 525 60 ) ) -RRB- cord-022526-j9kg00qf 525 61 . . . cord-022526-j9kg00qf 526 1 Mast mast NN cord-022526-j9kg00qf 526 2 cells cell NNS cord-022526-j9kg00qf 526 3 strategically strategically RB cord-022526-j9kg00qf 526 4 reside reside VBP cord-022526-j9kg00qf 526 5 in in IN cord-022526-j9kg00qf 526 6 mucosal mucosal JJ cord-022526-j9kg00qf 526 7 tissues tissue NNS cord-022526-j9kg00qf 526 8 , , , cord-022526-j9kg00qf 526 9 including include VBG cord-022526-j9kg00qf 526 10 the the DT cord-022526-j9kg00qf 526 11 submucosa submucosa JJ cord-022526-j9kg00qf 526 12 and and CC cord-022526-j9kg00qf 526 13 lamina lamina JJ cord-022526-j9kg00qf 526 14 propria propria FW cord-022526-j9kg00qf 526 15 of of IN cord-022526-j9kg00qf 526 16 the the DT cord-022526-j9kg00qf 526 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 526 18 tract tract NN cord-022526-j9kg00qf 526 19 , , , cord-022526-j9kg00qf 526 20 and and CC cord-022526-j9kg00qf 526 21 constitute constitute VBP cord-022526-j9kg00qf 526 22 a a DT cord-022526-j9kg00qf 526 23 crucial crucial JJ cord-022526-j9kg00qf 526 24 first first JJ cord-022526-j9kg00qf 526 25 line line NN cord-022526-j9kg00qf 526 26 of of IN cord-022526-j9kg00qf 526 27 defense defense NN cord-022526-j9kg00qf 526 28 at at IN cord-022526-j9kg00qf 526 29 epithelial epithelial JJ cord-022526-j9kg00qf 526 30 barriers barrier NNS cord-022526-j9kg00qf 526 31 . . . cord-022526-j9kg00qf 527 1 However however RB cord-022526-j9kg00qf 527 2 , , , cord-022526-j9kg00qf 527 3 they -PRON- PRP cord-022526-j9kg00qf 527 4 are be VBP cord-022526-j9kg00qf 527 5 also also RB cord-022526-j9kg00qf 527 6 important important JJ cord-022526-j9kg00qf 527 7 effector effector NN cord-022526-j9kg00qf 527 8 cells cell NNS cord-022526-j9kg00qf 527 9 of of IN cord-022526-j9kg00qf 527 10 the the DT cord-022526-j9kg00qf 527 11 pathophysiology pathophysiology NN cord-022526-j9kg00qf 527 12 of of IN cord-022526-j9kg00qf 527 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 527 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 527 15 diseases disease NNS cord-022526-j9kg00qf 527 16 . . . cord-022526-j9kg00qf 528 1 36 36 CD cord-022526-j9kg00qf 528 2 Experimental experimental JJ cord-022526-j9kg00qf 528 3 depletion depletion NN cord-022526-j9kg00qf 528 4 of of IN cord-022526-j9kg00qf 528 5 mast mast NN cord-022526-j9kg00qf 528 6 cells cell NNS cord-022526-j9kg00qf 528 7 , , , cord-022526-j9kg00qf 528 8 genetic genetic JJ cord-022526-j9kg00qf 528 9 deficiency deficiency NN cord-022526-j9kg00qf 528 10 in in IN cord-022526-j9kg00qf 528 11 the the DT cord-022526-j9kg00qf 528 12 development development NN cord-022526-j9kg00qf 528 13 of of IN cord-022526-j9kg00qf 528 14 mast mast NN cord-022526-j9kg00qf 528 15 cells cell NNS cord-022526-j9kg00qf 528 16 , , , cord-022526-j9kg00qf 528 17 or or CC cord-022526-j9kg00qf 528 18 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 528 19 stabilization stabilization NN cord-022526-j9kg00qf 528 20 of of IN cord-022526-j9kg00qf 528 21 mast mast NN cord-022526-j9kg00qf 528 22 cells cell NNS cord-022526-j9kg00qf 528 23 to to TO cord-022526-j9kg00qf 528 24 prevent prevent VB cord-022526-j9kg00qf 528 25 degranulation degranulation NN cord-022526-j9kg00qf 528 26 have have VB cord-022526-j9kg00qf 528 27 a a DT cord-022526-j9kg00qf 528 28 protective protective JJ cord-022526-j9kg00qf 528 29 effect effect NN cord-022526-j9kg00qf 528 30 in in IN cord-022526-j9kg00qf 528 31 a a DT cord-022526-j9kg00qf 528 32 variety variety NN cord-022526-j9kg00qf 528 33 of of IN cord-022526-j9kg00qf 528 34 models model NNS cord-022526-j9kg00qf 528 35 of of IN cord-022526-j9kg00qf 528 36 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 528 37 inflammatory inflammatory JJ cord-022526-j9kg00qf 528 38 disease disease NN cord-022526-j9kg00qf 528 39 , , , cord-022526-j9kg00qf 528 40 including include VBG cord-022526-j9kg00qf 528 41 dextran dextran NN cord-022526-j9kg00qf 528 42 - - : cord-022526-j9kg00qf 528 43 or or CC cord-022526-j9kg00qf 528 44 trinitrobenzenesulfonic trinitrobenzenesulfonic JJ cord-022526-j9kg00qf 528 45 acid acid NN cord-022526-j9kg00qf 528 46 - - HYPH cord-022526-j9kg00qf 528 47 induced induce VBN cord-022526-j9kg00qf 528 48 colitis colitis NN cord-022526-j9kg00qf 528 49 , , , cord-022526-j9kg00qf 528 50 37 37 CD cord-022526-j9kg00qf 528 51 , , , cord-022526-j9kg00qf 528 52 38 38 CD cord-022526-j9kg00qf 528 53 ischemia ischemia NN cord-022526-j9kg00qf 528 54 - - HYPH cord-022526-j9kg00qf 528 55 reperfusion reperfusion NN cord-022526-j9kg00qf 528 56 injury injury NN cord-022526-j9kg00qf 528 57 , , , cord-022526-j9kg00qf 528 58 39 39 CD cord-022526-j9kg00qf 528 59 , , , cord-022526-j9kg00qf 528 60 40 40 CD cord-022526-j9kg00qf 528 61 and and CC cord-022526-j9kg00qf 528 62 immediate immediate JJ cord-022526-j9kg00qf 528 63 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 528 64 responses response NNS cord-022526-j9kg00qf 528 65 . . . cord-022526-j9kg00qf 529 1 41 41 CD cord-022526-j9kg00qf 529 2 Mast Mast NNP cord-022526-j9kg00qf 529 3 cells cell NNS cord-022526-j9kg00qf 529 4 are be VBP cord-022526-j9kg00qf 529 5 activated activate VBN cord-022526-j9kg00qf 529 6 by by IN cord-022526-j9kg00qf 529 7 a a DT cord-022526-j9kg00qf 529 8 wide wide JJ cord-022526-j9kg00qf 529 9 variety variety NN cord-022526-j9kg00qf 529 10 of of IN cord-022526-j9kg00qf 529 11 microbial microbial JJ cord-022526-j9kg00qf 529 12 products product NNS cord-022526-j9kg00qf 529 13 and and CC cord-022526-j9kg00qf 529 14 host host NN cord-022526-j9kg00qf 529 15 - - HYPH cord-022526-j9kg00qf 529 16 derived derive VBN cord-022526-j9kg00qf 529 17 mediators mediator NNS cord-022526-j9kg00qf 529 18 . . . cord-022526-j9kg00qf 530 1 42 42 CD cord-022526-j9kg00qf 531 1 Among among IN cord-022526-j9kg00qf 531 2 the the DT cord-022526-j9kg00qf 531 3 activators activator NNS cord-022526-j9kg00qf 531 4 of of IN cord-022526-j9kg00qf 531 5 mast mast NN cord-022526-j9kg00qf 531 6 cells cell NNS cord-022526-j9kg00qf 531 7 the the DT cord-022526-j9kg00qf 531 8 so so RB cord-022526-j9kg00qf 531 9 - - HYPH cord-022526-j9kg00qf 531 10 called call VBN cord-022526-j9kg00qf 531 11 anaphylatoxins anaphylatoxin NNS cord-022526-j9kg00qf 531 12 ( ( -LRB- cord-022526-j9kg00qf 531 13 complement complement NN cord-022526-j9kg00qf 531 14 fragments fragment NNS cord-022526-j9kg00qf 531 15 C3a C3a NNP cord-022526-j9kg00qf 531 16 , , , cord-022526-j9kg00qf 531 17 C5a C5a NNS cord-022526-j9kg00qf 531 18 , , , cord-022526-j9kg00qf 531 19 and and CC cord-022526-j9kg00qf 531 20 C4a C4a NNP cord-022526-j9kg00qf 531 21 ) ) -RRB- cord-022526-j9kg00qf 531 22 , , , cord-022526-j9kg00qf 531 23 are be VBP cord-022526-j9kg00qf 531 24 potent potent JJ cord-022526-j9kg00qf 531 25 stimuli stimulus NNS cord-022526-j9kg00qf 531 26 causing cause VBG cord-022526-j9kg00qf 531 27 release release NN cord-022526-j9kg00qf 531 28 of of IN cord-022526-j9kg00qf 531 29 mediators mediator NNS cord-022526-j9kg00qf 531 30 of of IN cord-022526-j9kg00qf 531 31 inflammation inflammation NN cord-022526-j9kg00qf 531 32 . . . cord-022526-j9kg00qf 532 1 In in IN cord-022526-j9kg00qf 532 2 addition addition NN cord-022526-j9kg00qf 532 3 , , , cord-022526-j9kg00qf 532 4 mast mast NN cord-022526-j9kg00qf 532 5 cells cell NNS cord-022526-j9kg00qf 532 6 are be VBP cord-022526-j9kg00qf 532 7 the the DT cord-022526-j9kg00qf 532 8 primary primary JJ cord-022526-j9kg00qf 532 9 effector effector NN cord-022526-j9kg00qf 532 10 cells cell NNS cord-022526-j9kg00qf 532 11 of of IN cord-022526-j9kg00qf 532 12 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 532 13 E e NN cord-022526-j9kg00qf 532 14 - - HYPH cord-022526-j9kg00qf 532 15 mediated mediate VBN cord-022526-j9kg00qf 532 16 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 532 17 ( ( -LRB- cord-022526-j9kg00qf 532 18 type type NN cord-022526-j9kg00qf 532 19 I -PRON- PRP cord-022526-j9kg00qf 532 20 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 532 21 reactions reaction NNS cord-022526-j9kg00qf 532 22 ) ) -RRB- cord-022526-j9kg00qf 532 23 by by IN cord-022526-j9kg00qf 532 24 virtue virtue NN cord-022526-j9kg00qf 532 25 of of IN cord-022526-j9kg00qf 532 26 their -PRON- PRP$ cord-022526-j9kg00qf 532 27 high high JJ cord-022526-j9kg00qf 532 28 affinity affinity NN cord-022526-j9kg00qf 532 29 receptors receptor NNS cord-022526-j9kg00qf 532 30 for for IN cord-022526-j9kg00qf 532 31 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 532 32 E. E. NNP cord-022526-j9kg00qf 532 33 Cross Cross NNP cord-022526-j9kg00qf 532 34 - - HYPH cord-022526-j9kg00qf 532 35 linking linking NN cord-022526-j9kg00qf 532 36 of of IN cord-022526-j9kg00qf 532 37 receptor receptor NN cord-022526-j9kg00qf 532 38 - - HYPH cord-022526-j9kg00qf 532 39 bound bind VBN cord-022526-j9kg00qf 532 40 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 532 41 E e NN cord-022526-j9kg00qf 532 42 on on IN cord-022526-j9kg00qf 532 43 mast mast JJ cord-022526-j9kg00qf 532 44 cell cell NN cord-022526-j9kg00qf 532 45 surface surface NN cord-022526-j9kg00qf 532 46 by by IN cord-022526-j9kg00qf 532 47 antigens antigen NNS cord-022526-j9kg00qf 532 48 ( ( -LRB- cord-022526-j9kg00qf 532 49 i.e. i.e. FW cord-022526-j9kg00qf 532 50 , , , cord-022526-j9kg00qf 532 51 food food NN cord-022526-j9kg00qf 532 52 antigens antigen NNS cord-022526-j9kg00qf 532 53 ) ) -RRB- cord-022526-j9kg00qf 532 54 causes cause VBZ cord-022526-j9kg00qf 532 55 rapid rapid JJ cord-022526-j9kg00qf 532 56 degranulation degranulation NN cord-022526-j9kg00qf 532 57 , , , cord-022526-j9kg00qf 532 58 resulting result VBG cord-022526-j9kg00qf 532 59 in in IN cord-022526-j9kg00qf 532 60 the the DT cord-022526-j9kg00qf 532 61 explosive explosive JJ cord-022526-j9kg00qf 532 62 release release NN cord-022526-j9kg00qf 532 63 of of IN cord-022526-j9kg00qf 532 64 granule granule NN cord-022526-j9kg00qf 532 65 contents content NNS cord-022526-j9kg00qf 532 66 . . . cord-022526-j9kg00qf 533 1 43 43 CD cord-022526-j9kg00qf 533 2 Neural neural JJ cord-022526-j9kg00qf 533 3 pathways pathway NNS cord-022526-j9kg00qf 533 4 in in IN cord-022526-j9kg00qf 533 5 the the DT cord-022526-j9kg00qf 533 6 intestine intestine NN cord-022526-j9kg00qf 533 7 also also RB cord-022526-j9kg00qf 533 8 regulate regulate VBP cord-022526-j9kg00qf 533 9 mast mast NN cord-022526-j9kg00qf 533 10 cells cell NNS cord-022526-j9kg00qf 533 11 . . . cord-022526-j9kg00qf 534 1 Mast mast NN cord-022526-j9kg00qf 534 2 cells cell NNS cord-022526-j9kg00qf 534 3 respond respond VBP cord-022526-j9kg00qf 534 4 to to IN cord-022526-j9kg00qf 534 5 enteric enteric JJ cord-022526-j9kg00qf 534 6 pathogen pathogen NN cord-022526-j9kg00qf 534 7 invasion invasion NN cord-022526-j9kg00qf 534 8 via via IN cord-022526-j9kg00qf 534 9 neural neural JJ cord-022526-j9kg00qf 534 10 reflexes reflex NNS cord-022526-j9kg00qf 534 11 that that WDT cord-022526-j9kg00qf 534 12 stimulate stimulate VBP cord-022526-j9kg00qf 534 13 the the DT cord-022526-j9kg00qf 534 14 release release NN cord-022526-j9kg00qf 534 15 of of IN cord-022526-j9kg00qf 534 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 534 17 mediators mediator NNS cord-022526-j9kg00qf 534 18 . . . cord-022526-j9kg00qf 535 1 Activated activate VBN cord-022526-j9kg00qf 535 2 mast mast NN cord-022526-j9kg00qf 535 3 cells cell NNS cord-022526-j9kg00qf 535 4 release release VBP cord-022526-j9kg00qf 535 5 preformed preformed JJ cord-022526-j9kg00qf 535 6 histamine histamine NN cord-022526-j9kg00qf 535 7 , , , cord-022526-j9kg00qf 535 8 5-hydroxytryptamine 5-hydroxytryptamine CD cord-022526-j9kg00qf 535 9 , , , cord-022526-j9kg00qf 535 10 proteases protease NNS cord-022526-j9kg00qf 535 11 , , , cord-022526-j9kg00qf 535 12 heparin heparin NN cord-022526-j9kg00qf 535 13 , , , cord-022526-j9kg00qf 535 14 and and CC cord-022526-j9kg00qf 535 15 cytokines cytokine NNS cord-022526-j9kg00qf 535 16 from from IN cord-022526-j9kg00qf 535 17 granules granule NNS cord-022526-j9kg00qf 535 18 . . . cord-022526-j9kg00qf 536 1 Activation activation NN cord-022526-j9kg00qf 536 2 also also RB cord-022526-j9kg00qf 536 3 stimulates stimulate VBZ cord-022526-j9kg00qf 536 4 de de FW cord-022526-j9kg00qf 536 5 novo novo NNP cord-022526-j9kg00qf 536 6 synthesis synthesis NN cord-022526-j9kg00qf 536 7 of of IN cord-022526-j9kg00qf 536 8 a a DT cord-022526-j9kg00qf 536 9 range range NN cord-022526-j9kg00qf 536 10 of of IN cord-022526-j9kg00qf 536 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 536 12 mediators mediator NNS cord-022526-j9kg00qf 536 13 , , , cord-022526-j9kg00qf 536 14 including include VBG cord-022526-j9kg00qf 536 15 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 536 16 , , , cord-022526-j9kg00qf 536 17 platelet platelet NN cord-022526-j9kg00qf 536 18 - - HYPH cord-022526-j9kg00qf 536 19 activating activate VBG cord-022526-j9kg00qf 536 20 factor factor NN cord-022526-j9kg00qf 536 21 , , , cord-022526-j9kg00qf 536 22 and and CC cord-022526-j9kg00qf 536 23 leukotrienes leukotriene NNS cord-022526-j9kg00qf 536 24 . . . cord-022526-j9kg00qf 537 1 Transcription transcription NN cord-022526-j9kg00qf 537 2 of of IN cord-022526-j9kg00qf 537 3 a a DT cord-022526-j9kg00qf 537 4 number number NN cord-022526-j9kg00qf 537 5 of of IN cord-022526-j9kg00qf 537 6 peptide peptide NN cord-022526-j9kg00qf 537 7 mediators mediator NNS cord-022526-j9kg00qf 537 8 , , , cord-022526-j9kg00qf 537 9 such such JJ cord-022526-j9kg00qf 537 10 as as IN cord-022526-j9kg00qf 537 11 the the DT cord-022526-j9kg00qf 537 12 cytokines cytokine NNS cord-022526-j9kg00qf 537 13 TNF TNF NNP cord-022526-j9kg00qf 537 14 - - HYPH cord-022526-j9kg00qf 537 15 α α NNP cord-022526-j9kg00qf 537 16 and and CC cord-022526-j9kg00qf 537 17 IL-1β il-1β NN cord-022526-j9kg00qf 537 18 among among IN cord-022526-j9kg00qf 537 19 many many JJ cord-022526-j9kg00qf 537 20 others other NNS cord-022526-j9kg00qf 537 21 , , , cord-022526-j9kg00qf 537 22 also also RB cord-022526-j9kg00qf 537 23 increases increase VBZ cord-022526-j9kg00qf 537 24 on on IN cord-022526-j9kg00qf 537 25 stimulation stimulation NN cord-022526-j9kg00qf 537 26 of of IN cord-022526-j9kg00qf 537 27 mast mast NN cord-022526-j9kg00qf 537 28 cells cell NNS cord-022526-j9kg00qf 537 29 . . . cord-022526-j9kg00qf 538 1 Mast mast JJ cord-022526-j9kg00qf 538 2 cell cell NN cord-022526-j9kg00qf 538 3 products product NNS cord-022526-j9kg00qf 538 4 have have VBP cord-022526-j9kg00qf 538 5 profound profound JJ cord-022526-j9kg00qf 538 6 effects effect NNS cord-022526-j9kg00qf 538 7 on on IN cord-022526-j9kg00qf 538 8 the the DT cord-022526-j9kg00qf 538 9 vasculature vasculature NN cord-022526-j9kg00qf 538 10 , , , cord-022526-j9kg00qf 538 11 increasing increase VBG cord-022526-j9kg00qf 538 12 endothelial endothelial JJ cord-022526-j9kg00qf 538 13 permeability permeability NN cord-022526-j9kg00qf 538 14 and and CC cord-022526-j9kg00qf 538 15 causing cause VBG cord-022526-j9kg00qf 538 16 vasodilation vasodilation NN cord-022526-j9kg00qf 538 17 . . . cord-022526-j9kg00qf 539 1 44 44 CD cord-022526-j9kg00qf 540 1 Moreover moreover RB cord-022526-j9kg00qf 540 2 , , , cord-022526-j9kg00qf 540 3 mast mast JJ cord-022526-j9kg00qf 540 4 cell cell NN cord-022526-j9kg00qf 540 5 - - HYPH cord-022526-j9kg00qf 540 6 derived derive VBN cord-022526-j9kg00qf 540 7 mediators mediator NNS cord-022526-j9kg00qf 540 8 greatly greatly RB cord-022526-j9kg00qf 540 9 enhance enhance VBP cord-022526-j9kg00qf 540 10 epithelial epithelial JJ cord-022526-j9kg00qf 540 11 secretion secretion NN cord-022526-j9kg00qf 540 12 by by IN cord-022526-j9kg00qf 540 13 a a DT cord-022526-j9kg00qf 540 14 mechanism mechanism NN cord-022526-j9kg00qf 540 15 that that WDT cord-022526-j9kg00qf 540 16 activates activate VBZ cord-022526-j9kg00qf 540 17 neural neural JJ cord-022526-j9kg00qf 540 18 pathways pathway NNS cord-022526-j9kg00qf 540 19 of of IN cord-022526-j9kg00qf 540 20 epithelial epithelial JJ cord-022526-j9kg00qf 540 21 secretion secretion NN cord-022526-j9kg00qf 540 22 and and CC cord-022526-j9kg00qf 540 23 directly directly RB cord-022526-j9kg00qf 540 24 stimulates stimulate VBZ cord-022526-j9kg00qf 540 25 epithelial epithelial JJ cord-022526-j9kg00qf 540 26 cells cell NNS cord-022526-j9kg00qf 540 27 . . . cord-022526-j9kg00qf 541 1 43 43 CD cord-022526-j9kg00qf 541 2 Mast mast JJ cord-022526-j9kg00qf 541 3 cell cell NN cord-022526-j9kg00qf 541 4 products product NNS cord-022526-j9kg00qf 541 5 significantly significantly RB cord-022526-j9kg00qf 541 6 alter alter VBP cord-022526-j9kg00qf 541 7 intestinal intestinal JJ cord-022526-j9kg00qf 541 8 motility motility NN cord-022526-j9kg00qf 541 9 , , , cord-022526-j9kg00qf 541 10 generally generally RB cord-022526-j9kg00qf 541 11 increasing increase VBG cord-022526-j9kg00qf 541 12 transit transit NN cord-022526-j9kg00qf 541 13 and and CC cord-022526-j9kg00qf 541 14 expulsion expulsion NN cord-022526-j9kg00qf 541 15 of of IN cord-022526-j9kg00qf 541 16 intestinal intestinal JJ cord-022526-j9kg00qf 541 17 contents content NNS cord-022526-j9kg00qf 541 18 . . . cord-022526-j9kg00qf 542 1 Mast mast JJ cord-022526-j9kg00qf 542 2 cell cell NN cord-022526-j9kg00qf 542 3 - - HYPH cord-022526-j9kg00qf 542 4 derived derive VBN cord-022526-j9kg00qf 542 5 leukotrienes leukotriene NNS cord-022526-j9kg00qf 542 6 and and CC cord-022526-j9kg00qf 542 7 TNF TNF NNP cord-022526-j9kg00qf 542 8 - - HYPH cord-022526-j9kg00qf 542 9 α α NNP cord-022526-j9kg00qf 542 10 also also RB cord-022526-j9kg00qf 542 11 have have VBP cord-022526-j9kg00qf 542 12 a a DT cord-022526-j9kg00qf 542 13 crucial crucial JJ cord-022526-j9kg00qf 542 14 role role NN cord-022526-j9kg00qf 542 15 in in IN cord-022526-j9kg00qf 542 16 host host NN cord-022526-j9kg00qf 542 17 defense defense NN cord-022526-j9kg00qf 542 18 against against IN cord-022526-j9kg00qf 542 19 bacterial bacterial JJ cord-022526-j9kg00qf 542 20 pathogens pathogen NNS cord-022526-j9kg00qf 542 21 , , , cord-022526-j9kg00qf 542 22 acting act VBG cord-022526-j9kg00qf 542 23 to to TO cord-022526-j9kg00qf 542 24 recruit recruit VB cord-022526-j9kg00qf 542 25 and and CC cord-022526-j9kg00qf 542 26 activate activate VB cord-022526-j9kg00qf 542 27 neutrophils neutrophil NNS cord-022526-j9kg00qf 542 28 . . . cord-022526-j9kg00qf 543 1 45 45 CD cord-022526-j9kg00qf 543 2 , , , cord-022526-j9kg00qf 543 3 46 46 CD cord-022526-j9kg00qf 543 4 Mast Mast NNP cord-022526-j9kg00qf 543 5 cells cell NNS cord-022526-j9kg00qf 543 6 have have VBP cord-022526-j9kg00qf 543 7 a a DT cord-022526-j9kg00qf 543 8 newly newly RB cord-022526-j9kg00qf 543 9 identified identify VBN cord-022526-j9kg00qf 543 10 role role NN cord-022526-j9kg00qf 543 11 in in IN cord-022526-j9kg00qf 543 12 host host NN cord-022526-j9kg00qf 543 13 defense defense NN cord-022526-j9kg00qf 543 14 and and CC cord-022526-j9kg00qf 543 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 543 16 responses response NNS cord-022526-j9kg00qf 543 17 to to IN cord-022526-j9kg00qf 543 18 bacterial bacterial JJ cord-022526-j9kg00qf 543 19 pathogens pathogen NNS cord-022526-j9kg00qf 543 20 , , , cord-022526-j9kg00qf 543 21 which which WDT cord-022526-j9kg00qf 543 22 in in IN cord-022526-j9kg00qf 543 23 part part NN cord-022526-j9kg00qf 543 24 is be VBZ cord-022526-j9kg00qf 543 25 caused cause VBN cord-022526-j9kg00qf 543 26 by by IN cord-022526-j9kg00qf 543 27 the the DT cord-022526-j9kg00qf 543 28 release release NN cord-022526-j9kg00qf 543 29 of of IN cord-022526-j9kg00qf 543 30 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 543 31 mediators mediator NNS cord-022526-j9kg00qf 543 32 during during IN cord-022526-j9kg00qf 543 33 bacterial bacterial JJ cord-022526-j9kg00qf 543 34 infection infection NN cord-022526-j9kg00qf 543 35 , , , cord-022526-j9kg00qf 543 36 which which WDT cord-022526-j9kg00qf 543 37 is be VBZ cord-022526-j9kg00qf 543 38 critical critical JJ cord-022526-j9kg00qf 543 39 for for IN cord-022526-j9kg00qf 543 40 recruiting recruit VBG cord-022526-j9kg00qf 543 41 and and CC cord-022526-j9kg00qf 543 42 activating activate VBG cord-022526-j9kg00qf 543 43 other other JJ cord-022526-j9kg00qf 543 44 innate innate JJ cord-022526-j9kg00qf 543 45 host host NN cord-022526-j9kg00qf 543 46 defense defense NN cord-022526-j9kg00qf 543 47 cells cell NNS cord-022526-j9kg00qf 543 48 such such JJ cord-022526-j9kg00qf 543 49 as as IN cord-022526-j9kg00qf 543 50 neutrophils neutrophil NNS cord-022526-j9kg00qf 543 51 . . . cord-022526-j9kg00qf 544 1 However however RB cord-022526-j9kg00qf 544 2 , , , cord-022526-j9kg00qf 544 3 mast mast NN cord-022526-j9kg00qf 544 4 cells cell NNS cord-022526-j9kg00qf 544 5 are be VBP cord-022526-j9kg00qf 544 6 also also RB cord-022526-j9kg00qf 544 7 phagocytic phagocytic JJ cord-022526-j9kg00qf 544 8 , , , cord-022526-j9kg00qf 544 9 have have VBP cord-022526-j9kg00qf 544 10 microbicidal microbicidal NN cord-022526-j9kg00qf 544 11 properties property NNS cord-022526-j9kg00qf 544 12 , , , cord-022526-j9kg00qf 544 13 and and CC cord-022526-j9kg00qf 544 14 can can MD cord-022526-j9kg00qf 544 15 act act VB cord-022526-j9kg00qf 544 16 as as IN cord-022526-j9kg00qf 544 17 antigen antigen NN cord-022526-j9kg00qf 544 18 - - HYPH cord-022526-j9kg00qf 544 19 presenting present VBG cord-022526-j9kg00qf 544 20 cells cell NNS cord-022526-j9kg00qf 544 21 to to IN cord-022526-j9kg00qf 544 22 the the DT cord-022526-j9kg00qf 544 23 adaptive adaptive JJ cord-022526-j9kg00qf 544 24 immune immune JJ cord-022526-j9kg00qf 544 25 system system NN cord-022526-j9kg00qf 544 26 . . . cord-022526-j9kg00qf 545 1 47 47 CD cord-022526-j9kg00qf 546 1 Although although IN cord-022526-j9kg00qf 546 2 accumulating accumulate VBG cord-022526-j9kg00qf 546 3 evidence evidence NN cord-022526-j9kg00qf 546 4 was be VBD cord-022526-j9kg00qf 546 5 establishing establish VBG cord-022526-j9kg00qf 546 6 the the DT cord-022526-j9kg00qf 546 7 role role NN cord-022526-j9kg00qf 546 8 of of IN cord-022526-j9kg00qf 546 9 mast mast NN cord-022526-j9kg00qf 546 10 cells cell NNS cord-022526-j9kg00qf 546 11 in in IN cord-022526-j9kg00qf 546 12 innate innate JJ cord-022526-j9kg00qf 546 13 immunity immunity NN cord-022526-j9kg00qf 546 14 , , , cord-022526-j9kg00qf 546 15 a a DT cord-022526-j9kg00qf 546 16 seminal seminal JJ cord-022526-j9kg00qf 546 17 study study NN cord-022526-j9kg00qf 546 18 that that IN cord-022526-j9kg00qf 546 19 unconditionally unconditionally RB cord-022526-j9kg00qf 546 20 identified identify VBD cord-022526-j9kg00qf 546 21 the the DT cord-022526-j9kg00qf 546 22 importance importance NN cord-022526-j9kg00qf 546 23 of of IN cord-022526-j9kg00qf 546 24 mast mast NN cord-022526-j9kg00qf 546 25 cells cell NNS cord-022526-j9kg00qf 546 26 in in IN cord-022526-j9kg00qf 546 27 host host NN cord-022526-j9kg00qf 546 28 defense defense NN cord-022526-j9kg00qf 546 29 demonstrated demonstrate VBD cord-022526-j9kg00qf 546 30 that that IN cord-022526-j9kg00qf 546 31 mast mast JJ cord-022526-j9kg00qf 546 32 cell cell NN cord-022526-j9kg00qf 546 33 - - HYPH cord-022526-j9kg00qf 546 34 deficient deficient JJ cord-022526-j9kg00qf 546 35 W/ W/ NNP cord-022526-j9kg00qf 546 36 W W NNP cord-022526-j9kg00qf 546 37 v v NN cord-022526-j9kg00qf 546 38 mice mouse NNS cord-022526-j9kg00qf 546 39 have have VBP cord-022526-j9kg00qf 546 40 impaired impair VBN cord-022526-j9kg00qf 546 41 responses response NNS cord-022526-j9kg00qf 546 42 to to IN cord-022526-j9kg00qf 546 43 gram gram NN cord-022526-j9kg00qf 546 44 - - HYPH cord-022526-j9kg00qf 546 45 negative negative JJ cord-022526-j9kg00qf 546 46 bacterial bacterial JJ cord-022526-j9kg00qf 546 47 peritonitis peritonitis NN cord-022526-j9kg00qf 546 48 , , , cord-022526-j9kg00qf 546 49 resulting result VBG cord-022526-j9kg00qf 546 50 in in IN cord-022526-j9kg00qf 546 51 a a DT cord-022526-j9kg00qf 546 52 significant significant JJ cord-022526-j9kg00qf 546 53 increase increase NN cord-022526-j9kg00qf 546 54 in in IN cord-022526-j9kg00qf 546 55 mortality mortality NN cord-022526-j9kg00qf 546 56 . . . cord-022526-j9kg00qf 547 1 The the DT cord-022526-j9kg00qf 547 2 role role NN cord-022526-j9kg00qf 547 3 for for IN cord-022526-j9kg00qf 547 4 mast mast NN cord-022526-j9kg00qf 547 5 cells cell NNS cord-022526-j9kg00qf 547 6 in in IN cord-022526-j9kg00qf 547 7 host host NN cord-022526-j9kg00qf 547 8 protective protective JJ cord-022526-j9kg00qf 547 9 responses response NNS cord-022526-j9kg00qf 547 10 appears appear VBZ cord-022526-j9kg00qf 547 11 to to TO cord-022526-j9kg00qf 547 12 be be VB cord-022526-j9kg00qf 547 13 as as IN cord-022526-j9kg00qf 547 14 a a DT cord-022526-j9kg00qf 547 15 sensor sensor NN cord-022526-j9kg00qf 547 16 of of IN cord-022526-j9kg00qf 547 17 bacterial bacterial JJ cord-022526-j9kg00qf 547 18 invasion invasion NN cord-022526-j9kg00qf 547 19 . . . cord-022526-j9kg00qf 548 1 Unlike unlike IN cord-022526-j9kg00qf 548 2 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 548 3 E e NN cord-022526-j9kg00qf 548 4 - - HYPH cord-022526-j9kg00qf 548 5 mediated mediate VBN cord-022526-j9kg00qf 548 6 responses response NNS cord-022526-j9kg00qf 548 7 , , , cord-022526-j9kg00qf 548 8 bacterial bacterial JJ cord-022526-j9kg00qf 548 9 products product NNS cord-022526-j9kg00qf 548 10 seem seem VBP cord-022526-j9kg00qf 548 11 to to TO cord-022526-j9kg00qf 548 12 elicit elicit VB cord-022526-j9kg00qf 548 13 a a DT cord-022526-j9kg00qf 548 14 highly highly RB cord-022526-j9kg00qf 548 15 regulated regulated JJ cord-022526-j9kg00qf 548 16 and and CC cord-022526-j9kg00qf 548 17 selective selective JJ cord-022526-j9kg00qf 548 18 response response NN cord-022526-j9kg00qf 548 19 from from IN cord-022526-j9kg00qf 548 20 mast mast NN cord-022526-j9kg00qf 548 21 cells cell NNS cord-022526-j9kg00qf 548 22 . . . cord-022526-j9kg00qf 549 1 The the DT cord-022526-j9kg00qf 549 2 complement complement NN cord-022526-j9kg00qf 549 3 cascade cascade NN cord-022526-j9kg00qf 549 4 is be VBZ cord-022526-j9kg00qf 549 5 a a DT cord-022526-j9kg00qf 549 6 fundamental fundamental JJ cord-022526-j9kg00qf 549 7 part part NN cord-022526-j9kg00qf 549 8 of of IN cord-022526-j9kg00qf 549 9 the the DT cord-022526-j9kg00qf 549 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 549 11 response response NN cord-022526-j9kg00qf 549 12 . . . cord-022526-j9kg00qf 550 1 Activation activation NN cord-022526-j9kg00qf 550 2 of of IN cord-022526-j9kg00qf 550 3 the the DT cord-022526-j9kg00qf 550 4 complement complement NN cord-022526-j9kg00qf 550 5 cascade cascade NN cord-022526-j9kg00qf 550 6 by by IN cord-022526-j9kg00qf 550 7 immune immune JJ cord-022526-j9kg00qf 550 8 complexes complex NNS cord-022526-j9kg00qf 550 9 ( ( -LRB- cord-022526-j9kg00qf 550 10 classical classical JJ cord-022526-j9kg00qf 550 11 pathway pathway NN cord-022526-j9kg00qf 550 12 ) ) -RRB- cord-022526-j9kg00qf 550 13 or or CC cord-022526-j9kg00qf 550 14 by by IN cord-022526-j9kg00qf 550 15 bacteria bacteria NNS cord-022526-j9kg00qf 550 16 or or CC cord-022526-j9kg00qf 550 17 bacterial bacterial JJ cord-022526-j9kg00qf 550 18 products product NNS cord-022526-j9kg00qf 550 19 , , , cord-022526-j9kg00qf 550 20 polysaccharides polysaccharide NNS cord-022526-j9kg00qf 550 21 , , , cord-022526-j9kg00qf 550 22 viruses virus NNS cord-022526-j9kg00qf 550 23 , , , cord-022526-j9kg00qf 550 24 fungi fungus NNS cord-022526-j9kg00qf 550 25 , , , cord-022526-j9kg00qf 550 26 or or CC cord-022526-j9kg00qf 550 27 host host NN cord-022526-j9kg00qf 550 28 cells cell NNS cord-022526-j9kg00qf 550 29 ( ( -LRB- cord-022526-j9kg00qf 550 30 alternative alternative JJ cord-022526-j9kg00qf 550 31 pathway pathway NN cord-022526-j9kg00qf 550 32 ) ) -RRB- cord-022526-j9kg00qf 550 33 results result VBZ cord-022526-j9kg00qf 550 34 in in IN cord-022526-j9kg00qf 550 35 the the DT cord-022526-j9kg00qf 550 36 deposition deposition NN cord-022526-j9kg00qf 550 37 of of IN cord-022526-j9kg00qf 550 38 complement complement JJ cord-022526-j9kg00qf 550 39 proteins protein NNS cord-022526-j9kg00qf 550 40 on on IN cord-022526-j9kg00qf 550 41 the the DT cord-022526-j9kg00qf 550 42 activating activate VBG cord-022526-j9kg00qf 550 43 surface surface NN cord-022526-j9kg00qf 550 44 and and CC cord-022526-j9kg00qf 550 45 the the DT cord-022526-j9kg00qf 550 46 release release NN cord-022526-j9kg00qf 550 47 of of IN cord-022526-j9kg00qf 550 48 soluble soluble JJ cord-022526-j9kg00qf 550 49 proteolytic proteolytic JJ cord-022526-j9kg00qf 550 50 fragments fragment NNS cord-022526-j9kg00qf 550 51 of of IN cord-022526-j9kg00qf 550 52 several several JJ cord-022526-j9kg00qf 550 53 complement complement NN cord-022526-j9kg00qf 550 54 components component NNS cord-022526-j9kg00qf 550 55 . . . cord-022526-j9kg00qf 551 1 In in IN cord-022526-j9kg00qf 551 2 particular particular JJ cord-022526-j9kg00qf 551 3 , , , cord-022526-j9kg00qf 551 4 activation activation NN cord-022526-j9kg00qf 551 5 of of IN cord-022526-j9kg00qf 551 6 either either DT cord-022526-j9kg00qf 551 7 pathway pathway NN cord-022526-j9kg00qf 551 8 results result NNS cord-022526-j9kg00qf 551 9 in in IN cord-022526-j9kg00qf 551 10 the the DT cord-022526-j9kg00qf 551 11 deposition deposition NN cord-022526-j9kg00qf 551 12 of of IN cord-022526-j9kg00qf 551 13 various various JJ cord-022526-j9kg00qf 551 14 fragments fragment NNS cord-022526-j9kg00qf 551 15 of of IN cord-022526-j9kg00qf 551 16 the the DT cord-022526-j9kg00qf 551 17 complement complement JJ cord-022526-j9kg00qf 551 18 protein protein NN cord-022526-j9kg00qf 551 19 C3 C3 NNP cord-022526-j9kg00qf 551 20 , , , cord-022526-j9kg00qf 551 21 which which WDT cord-022526-j9kg00qf 551 22 are be VBP cord-022526-j9kg00qf 551 23 potent potent JJ cord-022526-j9kg00qf 551 24 activators activator NNS cord-022526-j9kg00qf 551 25 of of IN cord-022526-j9kg00qf 551 26 neutrophils neutrophil NNS cord-022526-j9kg00qf 551 27 and and CC cord-022526-j9kg00qf 551 28 monocytes monocyte NNS cord-022526-j9kg00qf 551 29 . . . cord-022526-j9kg00qf 552 1 48 48 CD cord-022526-j9kg00qf 552 2 Opsonization opsonization NN cord-022526-j9kg00qf 552 3 of of IN cord-022526-j9kg00qf 552 4 particles particle NNS cord-022526-j9kg00qf 552 5 with with IN cord-022526-j9kg00qf 552 6 C3 c3 NN cord-022526-j9kg00qf 552 7 fragments fragment NNS cord-022526-j9kg00qf 552 8 constitutes constitute VBZ cord-022526-j9kg00qf 552 9 a a DT cord-022526-j9kg00qf 552 10 major major JJ cord-022526-j9kg00qf 552 11 mechanism mechanism NN cord-022526-j9kg00qf 552 12 of of IN cord-022526-j9kg00qf 552 13 target target NN cord-022526-j9kg00qf 552 14 recognition recognition NN cord-022526-j9kg00qf 552 15 and and CC cord-022526-j9kg00qf 552 16 phagocyte phagocyte NNP cord-022526-j9kg00qf 552 17 activation activation NN cord-022526-j9kg00qf 552 18 . . . cord-022526-j9kg00qf 553 1 49 49 CD cord-022526-j9kg00qf 554 1 During during IN cord-022526-j9kg00qf 554 2 the the DT cord-022526-j9kg00qf 554 3 activation activation NN cord-022526-j9kg00qf 554 4 of of IN cord-022526-j9kg00qf 554 5 the the DT cord-022526-j9kg00qf 554 6 complement complement NN cord-022526-j9kg00qf 554 7 cascade cascade NN cord-022526-j9kg00qf 554 8 culminating culminate VBG cord-022526-j9kg00qf 554 9 in in IN cord-022526-j9kg00qf 554 10 deposition deposition NN cord-022526-j9kg00qf 554 11 of of IN cord-022526-j9kg00qf 554 12 C3 c3 NN cord-022526-j9kg00qf 554 13 , , , cord-022526-j9kg00qf 554 14 soluble soluble JJ cord-022526-j9kg00qf 554 15 fragments fragment NNS cord-022526-j9kg00qf 554 16 of of IN cord-022526-j9kg00qf 554 17 C3 c3 NN cord-022526-j9kg00qf 554 18 ( ( -LRB- cord-022526-j9kg00qf 554 19 C3a C3a NNP cord-022526-j9kg00qf 554 20 ) ) -RRB- cord-022526-j9kg00qf 554 21 , , , cord-022526-j9kg00qf 554 22 C5 C5 NNP cord-022526-j9kg00qf 554 23 ( ( -LRB- cord-022526-j9kg00qf 554 24 C5a C5a NNP cord-022526-j9kg00qf 554 25 ) ) -RRB- cord-022526-j9kg00qf 554 26 , , , cord-022526-j9kg00qf 554 27 and and CC cord-022526-j9kg00qf 554 28 C4 C4 NNP cord-022526-j9kg00qf 554 29 ( ( -LRB- cord-022526-j9kg00qf 554 30 C4a c4a NN cord-022526-j9kg00qf 554 31 ) ) -RRB- cord-022526-j9kg00qf 554 32 are be VBP cord-022526-j9kg00qf 554 33 liberated liberate VBN cord-022526-j9kg00qf 554 34 . . . cord-022526-j9kg00qf 555 1 These these DT cord-022526-j9kg00qf 555 2 fragments fragment NNS cord-022526-j9kg00qf 555 3 , , , cord-022526-j9kg00qf 555 4 termed term VBD cord-022526-j9kg00qf 555 5 anaphylatoxins anaphylatoxin NNS cord-022526-j9kg00qf 555 6 , , , cord-022526-j9kg00qf 555 7 have have VBP cord-022526-j9kg00qf 555 8 potent potent JJ cord-022526-j9kg00qf 555 9 effects effect NNS cord-022526-j9kg00qf 555 10 on on IN cord-022526-j9kg00qf 555 11 tissues tissue NNS cord-022526-j9kg00qf 555 12 and and CC cord-022526-j9kg00qf 555 13 cells cell NNS cord-022526-j9kg00qf 555 14 during during IN cord-022526-j9kg00qf 555 15 inflammation inflammation NN cord-022526-j9kg00qf 555 16 . . . cord-022526-j9kg00qf 556 1 Perhaps perhaps RB cord-022526-j9kg00qf 556 2 most most RBS cord-022526-j9kg00qf 556 3 notably notably RB cord-022526-j9kg00qf 556 4 , , , cord-022526-j9kg00qf 556 5 anaphylatoxins anaphylatoxin NNS cord-022526-j9kg00qf 556 6 are be VBP cord-022526-j9kg00qf 556 7 chemotactic chemotactic VBN cord-022526-j9kg00qf 556 8 for for IN cord-022526-j9kg00qf 556 9 neutrophils neutrophil NNS cord-022526-j9kg00qf 556 10 ( ( -LRB- cord-022526-j9kg00qf 556 11 particularly particularly RB cord-022526-j9kg00qf 556 12 C5a C5a NNS cord-022526-j9kg00qf 556 13 ) ) -RRB- cord-022526-j9kg00qf 556 14 , , , cord-022526-j9kg00qf 556 15 activate activate VBP cord-022526-j9kg00qf 556 16 neutrophil neutrophil NN cord-022526-j9kg00qf 556 17 and and CC cord-022526-j9kg00qf 556 18 mast mast NN cord-022526-j9kg00qf 556 19 cell cell NN cord-022526-j9kg00qf 556 20 degranulation degranulation NN cord-022526-j9kg00qf 556 21 , , , cord-022526-j9kg00qf 556 22 and and CC cord-022526-j9kg00qf 556 23 stimulate stimulate VB cord-022526-j9kg00qf 556 24 ROI ROI NNP cord-022526-j9kg00qf 556 25 release release NN cord-022526-j9kg00qf 556 26 from from IN cord-022526-j9kg00qf 556 27 neutrophils neutrophil NNS cord-022526-j9kg00qf 556 28 . . . cord-022526-j9kg00qf 557 1 48 48 CD cord-022526-j9kg00qf 558 1 The the DT cord-022526-j9kg00qf 558 2 termination termination NN cord-022526-j9kg00qf 558 3 of of IN cord-022526-j9kg00qf 558 4 the the DT cord-022526-j9kg00qf 558 5 complement complement NN cord-022526-j9kg00qf 558 6 cascade cascade NN cord-022526-j9kg00qf 558 7 results result NNS cord-022526-j9kg00qf 558 8 in in IN cord-022526-j9kg00qf 558 9 the the DT cord-022526-j9kg00qf 558 10 formation formation NN cord-022526-j9kg00qf 558 11 of of IN cord-022526-j9kg00qf 558 12 a a DT cord-022526-j9kg00qf 558 13 membrane membrane NN cord-022526-j9kg00qf 558 14 attack attack NN cord-022526-j9kg00qf 558 15 complex complex NN cord-022526-j9kg00qf 558 16 in in IN cord-022526-j9kg00qf 558 17 membranes membrane NNS cord-022526-j9kg00qf 558 18 at at IN cord-022526-j9kg00qf 558 19 the the DT cord-022526-j9kg00qf 558 20 site site NN cord-022526-j9kg00qf 558 21 of of IN cord-022526-j9kg00qf 558 22 complement complement JJ cord-022526-j9kg00qf 558 23 activation activation NN cord-022526-j9kg00qf 558 24 , , , cord-022526-j9kg00qf 558 25 and and CC cord-022526-j9kg00qf 558 26 if if IN cord-022526-j9kg00qf 558 27 this this DT cord-022526-j9kg00qf 558 28 occurs occur VBZ cord-022526-j9kg00qf 558 29 on on IN cord-022526-j9kg00qf 558 30 host host NN cord-022526-j9kg00qf 558 31 cells cell NNS cord-022526-j9kg00qf 558 32 such such JJ cord-022526-j9kg00qf 558 33 as as IN cord-022526-j9kg00qf 558 34 endothelium endothelium NN cord-022526-j9kg00qf 558 35 , , , cord-022526-j9kg00qf 558 36 it -PRON- PRP cord-022526-j9kg00qf 558 37 may may MD cord-022526-j9kg00qf 558 38 cause cause VB cord-022526-j9kg00qf 558 39 irreversible irreversible JJ cord-022526-j9kg00qf 558 40 cell cell NN cord-022526-j9kg00qf 558 41 injury injury NN cord-022526-j9kg00qf 558 42 . . . cord-022526-j9kg00qf 559 1 Although although IN cord-022526-j9kg00qf 559 2 the the DT cord-022526-j9kg00qf 559 3 primary primary JJ cord-022526-j9kg00qf 559 4 source source NN cord-022526-j9kg00qf 559 5 of of IN cord-022526-j9kg00qf 559 6 complement complement NN cord-022526-j9kg00qf 559 7 is be VBZ cord-022526-j9kg00qf 559 8 plasma plasma NN cord-022526-j9kg00qf 559 9 , , , cord-022526-j9kg00qf 559 10 epithelial epithelial JJ cord-022526-j9kg00qf 559 11 cells cell NNS cord-022526-j9kg00qf 559 12 of of IN cord-022526-j9kg00qf 559 13 the the DT cord-022526-j9kg00qf 559 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 559 15 tract tract NN cord-022526-j9kg00qf 559 16 also also RB cord-022526-j9kg00qf 559 17 produce produce VBP cord-022526-j9kg00qf 559 18 C3 C3 NNP cord-022526-j9kg00qf 559 19 , , , cord-022526-j9kg00qf 559 20 suggesting suggest VBG cord-022526-j9kg00qf 559 21 that that IN cord-022526-j9kg00qf 559 22 local local JJ cord-022526-j9kg00qf 559 23 production production NN cord-022526-j9kg00qf 559 24 and and CC cord-022526-j9kg00qf 559 25 activation activation NN cord-022526-j9kg00qf 559 26 of of IN cord-022526-j9kg00qf 559 27 the the DT cord-022526-j9kg00qf 559 28 complement complement NN cord-022526-j9kg00qf 559 29 cascade cascade NN cord-022526-j9kg00qf 559 30 during during IN cord-022526-j9kg00qf 559 31 inflammation inflammation NN cord-022526-j9kg00qf 559 32 occurs occur VBZ cord-022526-j9kg00qf 559 33 in in IN cord-022526-j9kg00qf 559 34 intestinal intestinal JJ cord-022526-j9kg00qf 559 35 tissues tissue NNS cord-022526-j9kg00qf 559 36 . . . cord-022526-j9kg00qf 560 1 Clearly clearly RB cord-022526-j9kg00qf 560 2 , , , cord-022526-j9kg00qf 560 3 if if IN cord-022526-j9kg00qf 560 4 the the DT cord-022526-j9kg00qf 560 5 regulatory regulatory JJ cord-022526-j9kg00qf 560 6 mechanisms mechanism NNS cord-022526-j9kg00qf 560 7 of of IN cord-022526-j9kg00qf 560 8 the the DT cord-022526-j9kg00qf 560 9 complement complement NN cord-022526-j9kg00qf 560 10 cascade cascade NN cord-022526-j9kg00qf 560 11 fail fail VBP cord-022526-j9kg00qf 560 12 , , , cord-022526-j9kg00qf 560 13 then then RB cord-022526-j9kg00qf 560 14 the the DT cord-022526-j9kg00qf 560 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 560 16 response response NN cord-022526-j9kg00qf 560 17 may may MD cord-022526-j9kg00qf 560 18 be be VB cord-022526-j9kg00qf 560 19 inappropriate inappropriate JJ cord-022526-j9kg00qf 560 20 and and CC cord-022526-j9kg00qf 560 21 tissue tissue NN cord-022526-j9kg00qf 560 22 injury injury NN cord-022526-j9kg00qf 560 23 can can MD cord-022526-j9kg00qf 560 24 occur occur VB cord-022526-j9kg00qf 560 25 . . . cord-022526-j9kg00qf 561 1 The the DT cord-022526-j9kg00qf 561 2 role role NN cord-022526-j9kg00qf 561 3 of of IN cord-022526-j9kg00qf 561 4 complement complement NN cord-022526-j9kg00qf 561 5 in in IN cord-022526-j9kg00qf 561 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 561 7 inflammation inflammation NN cord-022526-j9kg00qf 561 8 has have VBZ cord-022526-j9kg00qf 561 9 been be VBN cord-022526-j9kg00qf 561 10 most most RBS cord-022526-j9kg00qf 561 11 studied study VBN cord-022526-j9kg00qf 561 12 extensively extensively RB cord-022526-j9kg00qf 561 13 in in IN cord-022526-j9kg00qf 561 14 models model NNS cord-022526-j9kg00qf 561 15 of of IN cord-022526-j9kg00qf 561 16 ischemia ischemia NN cord-022526-j9kg00qf 561 17 - - HYPH cord-022526-j9kg00qf 561 18 reperfusion reperfusion NN cord-022526-j9kg00qf 561 19 injury injury NN cord-022526-j9kg00qf 561 20 . . . cord-022526-j9kg00qf 562 1 Activation activation NN cord-022526-j9kg00qf 562 2 of of IN cord-022526-j9kg00qf 562 3 the the DT cord-022526-j9kg00qf 562 4 complement complement NN cord-022526-j9kg00qf 562 5 cascades cascade NNS cord-022526-j9kg00qf 562 6 has have VBZ cord-022526-j9kg00qf 562 7 a a DT cord-022526-j9kg00qf 562 8 major major JJ cord-022526-j9kg00qf 562 9 role role NN cord-022526-j9kg00qf 562 10 in in IN cord-022526-j9kg00qf 562 11 altered alter VBN cord-022526-j9kg00qf 562 12 endothelial endothelial JJ cord-022526-j9kg00qf 562 13 and and CC cord-022526-j9kg00qf 562 14 epithelial epithelial JJ cord-022526-j9kg00qf 562 15 permeability permeability NN cord-022526-j9kg00qf 562 16 in in IN cord-022526-j9kg00qf 562 17 these these DT cord-022526-j9kg00qf 562 18 models model NNS cord-022526-j9kg00qf 562 19 . . . cord-022526-j9kg00qf 563 1 Several several JJ cord-022526-j9kg00qf 563 2 lines line NNS cord-022526-j9kg00qf 563 3 of of IN cord-022526-j9kg00qf 563 4 evidence evidence NN cord-022526-j9kg00qf 563 5 support support VBP cord-022526-j9kg00qf 563 6 the the DT cord-022526-j9kg00qf 563 7 importance importance NN cord-022526-j9kg00qf 563 8 of of IN cord-022526-j9kg00qf 563 9 complement complement NN cord-022526-j9kg00qf 563 10 in in IN cord-022526-j9kg00qf 563 11 intestinal intestinal JJ cord-022526-j9kg00qf 563 12 injury injury NN cord-022526-j9kg00qf 563 13 . . . cord-022526-j9kg00qf 564 1 Mice mouse NNS cord-022526-j9kg00qf 564 2 deficient deficient JJ cord-022526-j9kg00qf 564 3 in in IN cord-022526-j9kg00qf 564 4 C3 C3 NNP cord-022526-j9kg00qf 564 5 or or CC cord-022526-j9kg00qf 564 6 C4 C4 NNP cord-022526-j9kg00qf 564 7 are be VBP cord-022526-j9kg00qf 564 8 protected protect VBN cord-022526-j9kg00qf 564 9 against against IN cord-022526-j9kg00qf 564 10 ischemia ischemia NN cord-022526-j9kg00qf 564 11 - - HYPH cord-022526-j9kg00qf 564 12 reperfusion reperfusion NN cord-022526-j9kg00qf 564 13 injury injury NN cord-022526-j9kg00qf 564 14 . . . cord-022526-j9kg00qf 565 1 50 50 CD cord-022526-j9kg00qf 566 1 Moreover moreover RB cord-022526-j9kg00qf 566 2 , , , cord-022526-j9kg00qf 566 3 administration administration NN cord-022526-j9kg00qf 566 4 of of IN cord-022526-j9kg00qf 566 5 monoclonal monoclonal JJ cord-022526-j9kg00qf 566 6 antibodies antibody NNS cord-022526-j9kg00qf 566 7 against against IN cord-022526-j9kg00qf 566 8 C5 C5 NNP cord-022526-j9kg00qf 566 9 reduced reduce VBN cord-022526-j9kg00qf 566 10 local local JJ cord-022526-j9kg00qf 566 11 and and CC cord-022526-j9kg00qf 566 12 remote remote JJ cord-022526-j9kg00qf 566 13 injury injury NN cord-022526-j9kg00qf 566 14 and and CC cord-022526-j9kg00qf 566 15 inflammation inflammation NN cord-022526-j9kg00qf 566 16 during during IN cord-022526-j9kg00qf 566 17 intestinal intestinal JJ cord-022526-j9kg00qf 566 18 reperfusion reperfusion NN cord-022526-j9kg00qf 566 19 injury injury NN cord-022526-j9kg00qf 566 20 in in IN cord-022526-j9kg00qf 566 21 a a DT cord-022526-j9kg00qf 566 22 rat rat NN cord-022526-j9kg00qf 566 23 model model NN cord-022526-j9kg00qf 566 24 . . . cord-022526-j9kg00qf 567 1 51 51 CD cord-022526-j9kg00qf 567 2 Administration Administration NNP cord-022526-j9kg00qf 567 3 of of IN cord-022526-j9kg00qf 567 4 a a DT cord-022526-j9kg00qf 567 5 soluble soluble JJ cord-022526-j9kg00qf 567 6 form form NN cord-022526-j9kg00qf 567 7 of of IN cord-022526-j9kg00qf 567 8 complement complement JJ cord-022526-j9kg00qf 567 9 receptor receptor NN cord-022526-j9kg00qf 567 10 1 1 CD cord-022526-j9kg00qf 567 11 , , , cord-022526-j9kg00qf 567 12 a a DT cord-022526-j9kg00qf 567 13 regulatory regulatory JJ cord-022526-j9kg00qf 567 14 protein protein NN cord-022526-j9kg00qf 567 15 that that WDT cord-022526-j9kg00qf 567 16 halts halt VBZ cord-022526-j9kg00qf 567 17 the the DT cord-022526-j9kg00qf 567 18 complement complement NN cord-022526-j9kg00qf 567 19 cascade cascade NN cord-022526-j9kg00qf 567 20 by by IN cord-022526-j9kg00qf 567 21 dissociating dissociate VBG cord-022526-j9kg00qf 567 22 C3 C3 NNP cord-022526-j9kg00qf 567 23 and and CC cord-022526-j9kg00qf 567 24 C5 C5 NNP cord-022526-j9kg00qf 567 25 on on IN cord-022526-j9kg00qf 567 26 host host NN cord-022526-j9kg00qf 567 27 cell cell NN cord-022526-j9kg00qf 567 28 membranes membrane NNS cord-022526-j9kg00qf 567 29 , , , cord-022526-j9kg00qf 567 30 reduced reduce VBN cord-022526-j9kg00qf 567 31 mucosal mucosal JJ cord-022526-j9kg00qf 567 32 permeability permeability NN cord-022526-j9kg00qf 567 33 , , , cord-022526-j9kg00qf 567 34 neutrophil neutrophil NN cord-022526-j9kg00qf 567 35 influx influx NN cord-022526-j9kg00qf 567 36 , , , cord-022526-j9kg00qf 567 37 and and CC cord-022526-j9kg00qf 567 38 leukotriene leukotriene NN cord-022526-j9kg00qf 567 39 B b NN cord-022526-j9kg00qf 567 40 4 4 CD cord-022526-j9kg00qf 567 41 production production NN cord-022526-j9kg00qf 567 42 during during IN cord-022526-j9kg00qf 567 43 ischemia ischemia NN cord-022526-j9kg00qf 567 44 - - HYPH cord-022526-j9kg00qf 567 45 reperfusion reperfusion NN cord-022526-j9kg00qf 567 46 injury injury NN cord-022526-j9kg00qf 567 47 in in IN cord-022526-j9kg00qf 567 48 rats rat NNS cord-022526-j9kg00qf 567 49 and and CC cord-022526-j9kg00qf 567 50 mice mouse NNS cord-022526-j9kg00qf 567 51 . . . cord-022526-j9kg00qf 568 1 50 50 CD cord-022526-j9kg00qf 568 2 , , , cord-022526-j9kg00qf 568 3 52 52 CD cord-022526-j9kg00qf 569 1 Although although IN cord-022526-j9kg00qf 569 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 569 3 and and CC cord-022526-j9kg00qf 569 4 mast mast NN cord-022526-j9kg00qf 569 5 cells cell NNS cord-022526-j9kg00qf 569 6 mediate mediate VBP cord-022526-j9kg00qf 569 7 many many JJ cord-022526-j9kg00qf 569 8 of of IN cord-022526-j9kg00qf 569 9 the the DT cord-022526-j9kg00qf 569 10 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 569 11 effects effect NNS cord-022526-j9kg00qf 569 12 of of IN cord-022526-j9kg00qf 569 13 the the DT cord-022526-j9kg00qf 569 14 complement complement NN cord-022526-j9kg00qf 569 15 cascade cascade NN cord-022526-j9kg00qf 569 16 , , , cord-022526-j9kg00qf 569 17 the the DT cord-022526-j9kg00qf 569 18 membrane membrane NN cord-022526-j9kg00qf 569 19 attack attack NN cord-022526-j9kg00qf 569 20 complex complex NN cord-022526-j9kg00qf 569 21 may may MD cord-022526-j9kg00qf 569 22 have have VB cord-022526-j9kg00qf 569 23 a a DT cord-022526-j9kg00qf 569 24 primary primary JJ cord-022526-j9kg00qf 569 25 role role NN cord-022526-j9kg00qf 569 26 in in IN cord-022526-j9kg00qf 569 27 altered alter VBN cord-022526-j9kg00qf 569 28 vascular vascular JJ cord-022526-j9kg00qf 569 29 permeability permeability NN cord-022526-j9kg00qf 569 30 during during IN cord-022526-j9kg00qf 569 31 ischemia ischemia NN cord-022526-j9kg00qf 569 32 - - HYPH cord-022526-j9kg00qf 569 33 reperfusion reperfusion NN cord-022526-j9kg00qf 569 34 injury injury NN cord-022526-j9kg00qf 569 35 . . . cord-022526-j9kg00qf 570 1 53 53 CD cord-022526-j9kg00qf 570 2 Four four CD cord-022526-j9kg00qf 570 3 components component NNS cord-022526-j9kg00qf 570 4 initiate initiate VBP cord-022526-j9kg00qf 570 5 the the DT cord-022526-j9kg00qf 570 6 contact contact NN cord-022526-j9kg00qf 570 7 system system NN cord-022526-j9kg00qf 570 8 of of IN cord-022526-j9kg00qf 570 9 coagulation coagulation NN cord-022526-j9kg00qf 570 10 : : : cord-022526-j9kg00qf 571 1 Hageman Hageman NNP cord-022526-j9kg00qf 571 2 factor factor NN cord-022526-j9kg00qf 571 3 ( ( -LRB- cord-022526-j9kg00qf 571 4 HF HF NNP cord-022526-j9kg00qf 571 5 ) ) -RRB- cord-022526-j9kg00qf 571 6 , , , cord-022526-j9kg00qf 571 7 prekallikrein prekallikrein NNP cord-022526-j9kg00qf 571 8 , , , cord-022526-j9kg00qf 571 9 factor factor NN cord-022526-j9kg00qf 571 10 XI XI NNP cord-022526-j9kg00qf 571 11 , , , cord-022526-j9kg00qf 571 12 and and CC cord-022526-j9kg00qf 571 13 high high JJ cord-022526-j9kg00qf 571 14 - - HYPH cord-022526-j9kg00qf 571 15 molecular molecular JJ cord-022526-j9kg00qf 571 16 - - HYPH cord-022526-j9kg00qf 571 17 weight weight NN cord-022526-j9kg00qf 571 18 kininogen kininogen NN cord-022526-j9kg00qf 571 19 . . . cord-022526-j9kg00qf 572 1 HF HF NNP cord-022526-j9kg00qf 572 2 is be VBZ cord-022526-j9kg00qf 572 3 a a DT cord-022526-j9kg00qf 572 4 large large JJ cord-022526-j9kg00qf 572 5 plasma plasma NN cord-022526-j9kg00qf 572 6 glycoprotein glycoprotein NN cord-022526-j9kg00qf 572 7 that that WDT cord-022526-j9kg00qf 572 8 binds bind VBZ cord-022526-j9kg00qf 572 9 avidly avidly RB cord-022526-j9kg00qf 572 10 to to TO cord-022526-j9kg00qf 572 11 negatively negatively RB cord-022526-j9kg00qf 572 12 charged charge VBN cord-022526-j9kg00qf 572 13 surfaces surface NNS cord-022526-j9kg00qf 572 14 . . . cord-022526-j9kg00qf 573 1 54 54 CD cord-022526-j9kg00qf 573 2 Bacterial bacterial JJ cord-022526-j9kg00qf 573 3 cell cell NN cord-022526-j9kg00qf 573 4 walls wall NNS cord-022526-j9kg00qf 573 5 , , , cord-022526-j9kg00qf 573 6 vascular vascular JJ cord-022526-j9kg00qf 573 7 basement basement NN cord-022526-j9kg00qf 573 8 membranes membrane NNS cord-022526-j9kg00qf 573 9 , , , cord-022526-j9kg00qf 573 10 heparin heparin NN cord-022526-j9kg00qf 573 11 , , , cord-022526-j9kg00qf 573 12 glycosaminoglycans glycosaminoglycan NNS cord-022526-j9kg00qf 573 13 , , , cord-022526-j9kg00qf 573 14 and and CC cord-022526-j9kg00qf 573 15 other other JJ cord-022526-j9kg00qf 573 16 negatively negatively RB cord-022526-j9kg00qf 573 17 charged charge VBN cord-022526-j9kg00qf 573 18 surfaces surface NNS cord-022526-j9kg00qf 573 19 in in IN cord-022526-j9kg00qf 573 20 the the DT cord-022526-j9kg00qf 573 21 intestine intestine NN cord-022526-j9kg00qf 573 22 capture capture NN cord-022526-j9kg00qf 573 23 HF HF NNP cord-022526-j9kg00qf 573 24 and and CC cord-022526-j9kg00qf 573 25 the the DT cord-022526-j9kg00qf 573 26 other other JJ cord-022526-j9kg00qf 573 27 three three CD cord-022526-j9kg00qf 573 28 important important JJ cord-022526-j9kg00qf 573 29 initiators initiator NNS cord-022526-j9kg00qf 573 30 of of IN cord-022526-j9kg00qf 573 31 the the DT cord-022526-j9kg00qf 573 32 contact contact NN cord-022526-j9kg00qf 573 33 system system NN cord-022526-j9kg00qf 573 34 in in IN cord-022526-j9kg00qf 573 35 a a DT cord-022526-j9kg00qf 573 36 large large JJ cord-022526-j9kg00qf 573 37 multimolecular multimolecular JJ cord-022526-j9kg00qf 573 38 complex complex NN cord-022526-j9kg00qf 573 39 . . . cord-022526-j9kg00qf 574 1 Of of IN cord-022526-j9kg00qf 574 2 the the DT cord-022526-j9kg00qf 574 3 surfaces surface NNS cord-022526-j9kg00qf 574 4 that that WDT cord-022526-j9kg00qf 574 5 bind bind VBP cord-022526-j9kg00qf 574 6 HF HF NNP cord-022526-j9kg00qf 574 7 , , , cord-022526-j9kg00qf 574 8 the the DT cord-022526-j9kg00qf 574 9 extracellular extracellular JJ cord-022526-j9kg00qf 574 10 matrix matrix NN cord-022526-j9kg00qf 574 11 is be VBZ cord-022526-j9kg00qf 574 12 a a DT cord-022526-j9kg00qf 574 13 potent potent JJ cord-022526-j9kg00qf 574 14 activator activator NN cord-022526-j9kg00qf 574 15 of of IN cord-022526-j9kg00qf 574 16 the the DT cord-022526-j9kg00qf 574 17 contact contact NN cord-022526-j9kg00qf 574 18 system system NN cord-022526-j9kg00qf 574 19 . . . cord-022526-j9kg00qf 575 1 Once once RB cord-022526-j9kg00qf 575 2 bound bind VBN cord-022526-j9kg00qf 575 3 , , , cord-022526-j9kg00qf 575 4 HF HF NNP cord-022526-j9kg00qf 575 5 is be VBZ cord-022526-j9kg00qf 575 6 converted convert VBN cord-022526-j9kg00qf 575 7 to to IN cord-022526-j9kg00qf 575 8 HF HF NNP cord-022526-j9kg00qf 575 9 - - HYPH cord-022526-j9kg00qf 575 10 α α NNP cord-022526-j9kg00qf 575 11 , , , cord-022526-j9kg00qf 575 12 which which WDT cord-022526-j9kg00qf 575 13 cleaves cleave VBZ cord-022526-j9kg00qf 575 14 prekallikrein prekallikrein NNP cord-022526-j9kg00qf 575 15 to to IN cord-022526-j9kg00qf 575 16 kallikrein kallikrein NNP cord-022526-j9kg00qf 575 17 and and CC cord-022526-j9kg00qf 575 18 factor factor NN cord-022526-j9kg00qf 575 19 XI XI NNP cord-022526-j9kg00qf 575 20 to to TO cord-022526-j9kg00qf 575 21 factor factor NN cord-022526-j9kg00qf 575 22 XIa XIa NNS cord-022526-j9kg00qf 575 23 . . . cord-022526-j9kg00qf 576 1 The the DT cord-022526-j9kg00qf 576 2 ultimate ultimate JJ cord-022526-j9kg00qf 576 3 result result NN cord-022526-j9kg00qf 576 4 is be VBZ cord-022526-j9kg00qf 576 5 further further JJ cord-022526-j9kg00qf 576 6 cleavage cleavage NN cord-022526-j9kg00qf 576 7 of of IN cord-022526-j9kg00qf 576 8 HF HF NNP cord-022526-j9kg00qf 576 9 by by IN cord-022526-j9kg00qf 576 10 kallikrein kallikrein NNP cord-022526-j9kg00qf 576 11 and and CC cord-022526-j9kg00qf 576 12 triggering trigger VBG cord-022526-j9kg00qf 576 13 of of IN cord-022526-j9kg00qf 576 14 the the DT cord-022526-j9kg00qf 576 15 contact contact NN cord-022526-j9kg00qf 576 16 system system NN cord-022526-j9kg00qf 576 17 cascade cascade NN cord-022526-j9kg00qf 576 18 , , , cord-022526-j9kg00qf 576 19 activation activation NN cord-022526-j9kg00qf 576 20 of of IN cord-022526-j9kg00qf 576 21 intrinsic intrinsic JJ cord-022526-j9kg00qf 576 22 coagulation coagulation NN cord-022526-j9kg00qf 576 23 by by IN cord-022526-j9kg00qf 576 24 factor factor NN cord-022526-j9kg00qf 576 25 XIa XIa NNS cord-022526-j9kg00qf 576 26 , , , cord-022526-j9kg00qf 576 27 activation activation NN cord-022526-j9kg00qf 576 28 of of IN cord-022526-j9kg00qf 576 29 the the DT cord-022526-j9kg00qf 576 30 alternative alternative JJ cord-022526-j9kg00qf 576 31 pathway pathway NN cord-022526-j9kg00qf 576 32 by by IN cord-022526-j9kg00qf 576 33 HF HF NNP cord-022526-j9kg00qf 576 34 , , , cord-022526-j9kg00qf 576 35 and and CC cord-022526-j9kg00qf 576 36 proteolytic proteolytic JJ cord-022526-j9kg00qf 576 37 cleavage cleavage NN cord-022526-j9kg00qf 576 38 of of IN cord-022526-j9kg00qf 576 39 high high JJ cord-022526-j9kg00qf 576 40 - - HYPH cord-022526-j9kg00qf 576 41 molecular molecular JJ cord-022526-j9kg00qf 576 42 - - HYPH cord-022526-j9kg00qf 576 43 weight weight NN cord-022526-j9kg00qf 576 44 kininogen kininogen NNP cord-022526-j9kg00qf 576 45 by by IN cord-022526-j9kg00qf 576 46 kallikrein kallikrein NNP cord-022526-j9kg00qf 576 47 , , , cord-022526-j9kg00qf 576 48 releasing release VBG cord-022526-j9kg00qf 576 49 biologically biologically RB cord-022526-j9kg00qf 576 50 active active JJ cord-022526-j9kg00qf 576 51 kinins kinin NNS cord-022526-j9kg00qf 576 52 . . . cord-022526-j9kg00qf 577 1 The the DT cord-022526-j9kg00qf 577 2 products product NNS cord-022526-j9kg00qf 577 3 of of IN cord-022526-j9kg00qf 577 4 the the DT cord-022526-j9kg00qf 577 5 contact contact NN cord-022526-j9kg00qf 577 6 system system NN cord-022526-j9kg00qf 577 7 , , , cord-022526-j9kg00qf 577 8 particularly particularly RB cord-022526-j9kg00qf 577 9 bradykinin bradykinin NN cord-022526-j9kg00qf 577 10 , , , cord-022526-j9kg00qf 577 11 have have VBP cord-022526-j9kg00qf 577 12 several several JJ cord-022526-j9kg00qf 577 13 important important JJ cord-022526-j9kg00qf 577 14 biologic biologic JJ cord-022526-j9kg00qf 577 15 properties property NNS cord-022526-j9kg00qf 577 16 that that WDT cord-022526-j9kg00qf 577 17 drive drive VBP cord-022526-j9kg00qf 577 18 many many JJ cord-022526-j9kg00qf 577 19 of of IN cord-022526-j9kg00qf 577 20 the the DT cord-022526-j9kg00qf 577 21 vascular vascular JJ cord-022526-j9kg00qf 577 22 and and CC cord-022526-j9kg00qf 577 23 leukocytic leukocytic JJ cord-022526-j9kg00qf 577 24 responses response NNS cord-022526-j9kg00qf 577 25 during during IN cord-022526-j9kg00qf 577 26 inflammation inflammation NN cord-022526-j9kg00qf 577 27 . . . cord-022526-j9kg00qf 578 1 54 54 CD cord-022526-j9kg00qf 579 1 Bradykinin bradykinin NN cord-022526-j9kg00qf 579 2 induces induce VBZ cord-022526-j9kg00qf 579 3 endothelial endothelial JJ cord-022526-j9kg00qf 579 4 cell cell NN cord-022526-j9kg00qf 579 5 contracture contracture NN cord-022526-j9kg00qf 579 6 and and CC cord-022526-j9kg00qf 579 7 intracellular intracellular JJ cord-022526-j9kg00qf 579 8 tight tight JJ cord-022526-j9kg00qf 579 9 junction junction NN cord-022526-j9kg00qf 579 10 alterations alteration NNS cord-022526-j9kg00qf 579 11 that that WDT cord-022526-j9kg00qf 579 12 increase increase VBP cord-022526-j9kg00qf 579 13 vascular vascular JJ cord-022526-j9kg00qf 579 14 permeability permeability NN cord-022526-j9kg00qf 579 15 to to TO cord-022526-j9kg00qf 579 16 fluid fluid VB cord-022526-j9kg00qf 579 17 and and CC cord-022526-j9kg00qf 579 18 macromolecules macromolecule NNS cord-022526-j9kg00qf 579 19 . . . cord-022526-j9kg00qf 580 1 Bradykinin bradykinin NN cord-022526-j9kg00qf 580 2 also also RB cord-022526-j9kg00qf 580 3 affects affect VBZ cord-022526-j9kg00qf 580 4 vascular vascular JJ cord-022526-j9kg00qf 580 5 smooth smooth JJ cord-022526-j9kg00qf 580 6 muscle muscle NN cord-022526-j9kg00qf 580 7 contracture contracture NN cord-022526-j9kg00qf 580 8 , , , cord-022526-j9kg00qf 580 9 resulting result VBG cord-022526-j9kg00qf 580 10 in in IN cord-022526-j9kg00qf 580 11 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 580 12 or or CC cord-022526-j9kg00qf 580 13 vasodilation vasodilation NN cord-022526-j9kg00qf 580 14 depending depend VBG cord-022526-j9kg00qf 580 15 on on IN cord-022526-j9kg00qf 580 16 the the DT cord-022526-j9kg00qf 580 17 location location NN cord-022526-j9kg00qf 580 18 . . . cord-022526-j9kg00qf 581 1 Bradykinin bradykinin NN cord-022526-j9kg00qf 581 2 also also RB cord-022526-j9kg00qf 581 3 increases increase VBZ cord-022526-j9kg00qf 581 4 intestinal intestinal JJ cord-022526-j9kg00qf 581 5 motility motility NN cord-022526-j9kg00qf 581 6 , , , cord-022526-j9kg00qf 581 7 enhances enhance VBZ cord-022526-j9kg00qf 581 8 chloride chloride NN cord-022526-j9kg00qf 581 9 secretion secretion NN cord-022526-j9kg00qf 581 10 by by IN cord-022526-j9kg00qf 581 11 the the DT cord-022526-j9kg00qf 581 12 intestinal intestinal JJ cord-022526-j9kg00qf 581 13 mucosa mucosa NN cord-022526-j9kg00qf 581 14 , , , cord-022526-j9kg00qf 581 15 and and CC cord-022526-j9kg00qf 581 16 intensifies intensify VBZ cord-022526-j9kg00qf 581 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 581 18 pain pain NN cord-022526-j9kg00qf 581 19 . . . cord-022526-j9kg00qf 582 1 In in IN cord-022526-j9kg00qf 582 2 neutrophils neutrophil NNS cord-022526-j9kg00qf 582 3 , , , cord-022526-j9kg00qf 582 4 kinins kinin NNS cord-022526-j9kg00qf 582 5 stimulate stimulate VBP cord-022526-j9kg00qf 582 6 the the DT cord-022526-j9kg00qf 582 7 release release NN cord-022526-j9kg00qf 582 8 of of IN cord-022526-j9kg00qf 582 9 many many JJ cord-022526-j9kg00qf 582 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 582 11 mediators mediator NNS cord-022526-j9kg00qf 582 12 , , , cord-022526-j9kg00qf 582 13 including include VBG cord-022526-j9kg00qf 582 14 cytokines cytokine NNS cord-022526-j9kg00qf 582 15 , , , cord-022526-j9kg00qf 582 16 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 582 17 , , , cord-022526-j9kg00qf 582 18 leukotrienes leukotriene NNS cord-022526-j9kg00qf 582 19 , , , cord-022526-j9kg00qf 582 20 and and CC cord-022526-j9kg00qf 582 21 ROIs roi NNS cord-022526-j9kg00qf 582 22 . . . cord-022526-j9kg00qf 583 1 55 55 CD cord-022526-j9kg00qf 583 2 Kallikrein Kallikrein NNP cord-022526-j9kg00qf 583 3 cleaves cleave VBZ cord-022526-j9kg00qf 583 4 C5 C5 NNP cord-022526-j9kg00qf 583 5 to to TO cord-022526-j9kg00qf 583 6 release release VB cord-022526-j9kg00qf 583 7 C5a C5a NNS cord-022526-j9kg00qf 583 8 , , , cord-022526-j9kg00qf 583 9 a a DT cord-022526-j9kg00qf 583 10 potent potent JJ cord-022526-j9kg00qf 583 11 chemotactic chemotactic JJ cord-022526-j9kg00qf 583 12 factor factor NN cord-022526-j9kg00qf 583 13 for for IN cord-022526-j9kg00qf 583 14 neutrophils neutrophil NNS cord-022526-j9kg00qf 583 15 , , , cord-022526-j9kg00qf 583 16 and and CC cord-022526-j9kg00qf 583 17 thus thus RB cord-022526-j9kg00qf 583 18 has have VBZ cord-022526-j9kg00qf 583 19 a a DT cord-022526-j9kg00qf 583 20 role role NN cord-022526-j9kg00qf 583 21 in in IN cord-022526-j9kg00qf 583 22 recruiting recruit VBG cord-022526-j9kg00qf 583 23 and and CC cord-022526-j9kg00qf 583 24 activating activate VBG cord-022526-j9kg00qf 583 25 inflammatory inflammatory JJ cord-022526-j9kg00qf 583 26 leukocytes leukocyte NNS cord-022526-j9kg00qf 583 27 . . . cord-022526-j9kg00qf 584 1 The the DT cord-022526-j9kg00qf 584 2 plasma plasma NN cord-022526-j9kg00qf 584 3 kallikrein kallikrein NN cord-022526-j9kg00qf 584 4 - - HYPH cord-022526-j9kg00qf 584 5 bradykinin bradykinin NN cord-022526-j9kg00qf 584 6 system system NN cord-022526-j9kg00qf 584 7 is be VBZ cord-022526-j9kg00qf 584 8 activated activate VBN cord-022526-j9kg00qf 584 9 in in IN cord-022526-j9kg00qf 584 10 a a DT cord-022526-j9kg00qf 584 11 variety variety NN cord-022526-j9kg00qf 584 12 of of IN cord-022526-j9kg00qf 584 13 acute acute JJ cord-022526-j9kg00qf 584 14 and and CC cord-022526-j9kg00qf 584 15 chronic chronic JJ cord-022526-j9kg00qf 584 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 584 17 diseases disease NNS cord-022526-j9kg00qf 584 18 of of IN cord-022526-j9kg00qf 584 19 the the DT cord-022526-j9kg00qf 584 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 584 21 tract tract NN cord-022526-j9kg00qf 584 22 . . . cord-022526-j9kg00qf 585 1 56 56 CD cord-022526-j9kg00qf 585 2 , , , cord-022526-j9kg00qf 585 3 57 57 CD cord-022526-j9kg00qf 586 1 Recent recent JJ cord-022526-j9kg00qf 586 2 evidence evidence NN cord-022526-j9kg00qf 586 3 has have VBZ cord-022526-j9kg00qf 586 4 demonstrated demonstrate VBN cord-022526-j9kg00qf 586 5 that that IN cord-022526-j9kg00qf 586 6 blockade blockade NN cord-022526-j9kg00qf 586 7 of of IN cord-022526-j9kg00qf 586 8 the the DT cord-022526-j9kg00qf 586 9 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 586 10 effects effect NNS cord-022526-j9kg00qf 586 11 of of IN cord-022526-j9kg00qf 586 12 bradykinin bradykinin NN cord-022526-j9kg00qf 586 13 has have VBZ cord-022526-j9kg00qf 586 14 clinical clinical JJ cord-022526-j9kg00qf 586 15 applications application NNS cord-022526-j9kg00qf 586 16 . . . cord-022526-j9kg00qf 587 1 Oral oral JJ cord-022526-j9kg00qf 587 2 or or CC cord-022526-j9kg00qf 587 3 intravenous intravenous JJ cord-022526-j9kg00qf 587 4 administration administration NN cord-022526-j9kg00qf 587 5 of of IN cord-022526-j9kg00qf 587 6 the the DT cord-022526-j9kg00qf 587 7 bradykinin bradykinin NN cord-022526-j9kg00qf 587 8 receptor receptor NN cord-022526-j9kg00qf 587 9 antagonist antagonist NN cord-022526-j9kg00qf 587 10 icatibant icatibant XX cord-022526-j9kg00qf 587 11 reduces reduce VBZ cord-022526-j9kg00qf 587 12 the the DT cord-022526-j9kg00qf 587 13 clinical clinical JJ cord-022526-j9kg00qf 587 14 signs sign NNS cord-022526-j9kg00qf 587 15 , , , cord-022526-j9kg00qf 587 16 onset onset NN cord-022526-j9kg00qf 587 17 of of IN cord-022526-j9kg00qf 587 18 diarrhea diarrhea NN cord-022526-j9kg00qf 587 19 , , , cord-022526-j9kg00qf 587 20 and and CC cord-022526-j9kg00qf 587 21 many many JJ cord-022526-j9kg00qf 587 22 of of IN cord-022526-j9kg00qf 587 23 the the DT cord-022526-j9kg00qf 587 24 histopathologic histopathologic JJ cord-022526-j9kg00qf 587 25 changes change NNS cord-022526-j9kg00qf 587 26 in in IN cord-022526-j9kg00qf 587 27 experimental experimental JJ cord-022526-j9kg00qf 587 28 models model NNS cord-022526-j9kg00qf 587 29 of of IN cord-022526-j9kg00qf 587 30 colitis colitis NN cord-022526-j9kg00qf 587 31 in in IN cord-022526-j9kg00qf 587 32 mice mouse NNS cord-022526-j9kg00qf 587 33 . . . cord-022526-j9kg00qf 588 1 58 58 CD cord-022526-j9kg00qf 588 2 Inhibition inhibition NN cord-022526-j9kg00qf 588 3 of of IN cord-022526-j9kg00qf 588 4 kallikrein kallikrein NNP cord-022526-j9kg00qf 588 5 by by IN cord-022526-j9kg00qf 588 6 oral oral JJ cord-022526-j9kg00qf 588 7 administration administration NN cord-022526-j9kg00qf 588 8 of of IN cord-022526-j9kg00qf 588 9 P8720 P8720 NNP cord-022526-j9kg00qf 588 10 attenuated attenuate VBD cord-022526-j9kg00qf 588 11 the the DT cord-022526-j9kg00qf 588 12 intestinal intestinal JJ cord-022526-j9kg00qf 588 13 inflammation inflammation NN cord-022526-j9kg00qf 588 14 , , , cord-022526-j9kg00qf 588 15 clinical clinical JJ cord-022526-j9kg00qf 588 16 score score NN cord-022526-j9kg00qf 588 17 , , , cord-022526-j9kg00qf 588 18 and and CC cord-022526-j9kg00qf 588 19 systemic systemic JJ cord-022526-j9kg00qf 588 20 manifestations manifestation NNS cord-022526-j9kg00qf 588 21 in in IN cord-022526-j9kg00qf 588 22 a a DT cord-022526-j9kg00qf 588 23 model model NN cord-022526-j9kg00qf 588 24 of of IN cord-022526-j9kg00qf 588 25 chronic chronic JJ cord-022526-j9kg00qf 588 26 granulomatous granulomatous JJ cord-022526-j9kg00qf 588 27 enterocolitis enterocolitis NN cord-022526-j9kg00qf 588 28 . . . cord-022526-j9kg00qf 588 29 57 57 CD cord-022526-j9kg00qf 589 1 Thus thus RB cord-022526-j9kg00qf 589 2 the the DT cord-022526-j9kg00qf 589 3 contact contact NN cord-022526-j9kg00qf 589 4 system system NN cord-022526-j9kg00qf 589 5 is be VBZ cord-022526-j9kg00qf 589 6 a a DT cord-022526-j9kg00qf 589 7 viable viable JJ cord-022526-j9kg00qf 589 8 therapeutic therapeutic JJ cord-022526-j9kg00qf 589 9 target target NN cord-022526-j9kg00qf 589 10 for for IN cord-022526-j9kg00qf 589 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 589 12 diseases disease NNS cord-022526-j9kg00qf 589 13 of of IN cord-022526-j9kg00qf 589 14 the the DT cord-022526-j9kg00qf 589 15 intestine intestine NN cord-022526-j9kg00qf 589 16 . . . cord-022526-j9kg00qf 590 1 Changes change NNS cord-022526-j9kg00qf 590 2 in in IN cord-022526-j9kg00qf 590 3 blood blood NN cord-022526-j9kg00qf 590 4 flow flow NN cord-022526-j9kg00qf 590 5 to to IN cord-022526-j9kg00qf 590 6 the the DT cord-022526-j9kg00qf 590 7 mucosa mucosa JJ cord-022526-j9kg00qf 590 8 and and CC cord-022526-j9kg00qf 590 9 other other JJ cord-022526-j9kg00qf 590 10 regions region NNS cord-022526-j9kg00qf 590 11 of of IN cord-022526-j9kg00qf 590 12 the the DT cord-022526-j9kg00qf 590 13 intestine intestine NN cord-022526-j9kg00qf 590 14 that that WDT cord-022526-j9kg00qf 590 15 reduce reduce VBP cord-022526-j9kg00qf 590 16 perfusion perfusion NN cord-022526-j9kg00qf 590 17 of of IN cord-022526-j9kg00qf 590 18 the the DT cord-022526-j9kg00qf 590 19 tissues tissue NNS cord-022526-j9kg00qf 590 20 can can MD cord-022526-j9kg00qf 590 21 potentiate potentiate VB cord-022526-j9kg00qf 590 22 the the DT cord-022526-j9kg00qf 590 23 initial initial JJ cord-022526-j9kg00qf 590 24 damage damage NN cord-022526-j9kg00qf 590 25 caused cause VBN cord-022526-j9kg00qf 590 26 by by IN cord-022526-j9kg00qf 590 27 infection infection NN cord-022526-j9kg00qf 590 28 or or CC cord-022526-j9kg00qf 590 29 injury injury NN cord-022526-j9kg00qf 590 30 . . . cord-022526-j9kg00qf 591 1 For for IN cord-022526-j9kg00qf 591 2 example example NN cord-022526-j9kg00qf 591 3 , , , cord-022526-j9kg00qf 591 4 reperfusion reperfusion NN cord-022526-j9kg00qf 591 5 of of IN cord-022526-j9kg00qf 591 6 ischemic ischemic JJ cord-022526-j9kg00qf 591 7 tissues tissue NNS cord-022526-j9kg00qf 591 8 is be VBZ cord-022526-j9kg00qf 591 9 associated associate VBN cord-022526-j9kg00qf 591 10 with with IN cord-022526-j9kg00qf 591 11 platelet platelet NN cord-022526-j9kg00qf 591 12 and and CC cord-022526-j9kg00qf 591 13 neutrophil neutrophil NN cord-022526-j9kg00qf 591 14 clumping clumping NN cord-022526-j9kg00qf 591 15 in in IN cord-022526-j9kg00qf 591 16 the the DT cord-022526-j9kg00qf 591 17 small small JJ cord-022526-j9kg00qf 591 18 vessels vessel NNS cord-022526-j9kg00qf 591 19 of of IN cord-022526-j9kg00qf 591 20 the the DT cord-022526-j9kg00qf 591 21 mucosa mucosa NN cord-022526-j9kg00qf 591 22 , , , cord-022526-j9kg00qf 591 23 which which WDT cord-022526-j9kg00qf 591 24 can can MD cord-022526-j9kg00qf 591 25 impede impede VB cord-022526-j9kg00qf 591 26 blood blood NN cord-022526-j9kg00qf 591 27 flow flow NN cord-022526-j9kg00qf 591 28 . . . cord-022526-j9kg00qf 592 1 59 59 CD cord-022526-j9kg00qf 592 2 Platelets platelet NNS cord-022526-j9kg00qf 592 3 are be VBP cord-022526-j9kg00qf 592 4 activated activate VBN cord-022526-j9kg00qf 592 5 and and CC cord-022526-j9kg00qf 592 6 adhere adhere VB cord-022526-j9kg00qf 592 7 to to IN cord-022526-j9kg00qf 592 8 exposed expose VBN cord-022526-j9kg00qf 592 9 basement basement NN cord-022526-j9kg00qf 592 10 membrane membrane NN cord-022526-j9kg00qf 592 11 and and CC cord-022526-j9kg00qf 592 12 activated activate VBN cord-022526-j9kg00qf 592 13 endothelial endothelial JJ cord-022526-j9kg00qf 592 14 cells cell NNS cord-022526-j9kg00qf 592 15 and and CC cord-022526-j9kg00qf 592 16 provide provide VB cord-022526-j9kg00qf 592 17 a a DT cord-022526-j9kg00qf 592 18 surface surface NN cord-022526-j9kg00qf 592 19 for for IN cord-022526-j9kg00qf 592 20 leukocyte leukocyte NN cord-022526-j9kg00qf 592 21 adhesion adhesion NN cord-022526-j9kg00qf 592 22 . . . cord-022526-j9kg00qf 593 1 The the DT cord-022526-j9kg00qf 593 2 accumulation accumulation NN cord-022526-j9kg00qf 593 3 of of IN cord-022526-j9kg00qf 593 4 platelets platelet NNS cord-022526-j9kg00qf 593 5 and and CC cord-022526-j9kg00qf 593 6 leukocytes leukocyte NNS cord-022526-j9kg00qf 593 7 can can MD cord-022526-j9kg00qf 593 8 reduce reduce VB cord-022526-j9kg00qf 593 9 vessel vessel NN cord-022526-j9kg00qf 593 10 diameter diameter NN cord-022526-j9kg00qf 593 11 and and CC cord-022526-j9kg00qf 593 12 blood blood NN cord-022526-j9kg00qf 593 13 flow flow NN cord-022526-j9kg00qf 593 14 significantly significantly RB cord-022526-j9kg00qf 593 15 while while IN cord-022526-j9kg00qf 593 16 potentiating potentiate VBG cord-022526-j9kg00qf 593 17 local local JJ cord-022526-j9kg00qf 593 18 coagulation coagulation NN cord-022526-j9kg00qf 593 19 and and CC cord-022526-j9kg00qf 593 20 thrombus thrombus NN cord-022526-j9kg00qf 593 21 formation formation NN cord-022526-j9kg00qf 593 22 . . . cord-022526-j9kg00qf 594 1 Soluble soluble JJ cord-022526-j9kg00qf 594 2 mediators mediator NNS cord-022526-j9kg00qf 594 3 released release VBN cord-022526-j9kg00qf 594 4 by by IN cord-022526-j9kg00qf 594 5 activated activate VBN cord-022526-j9kg00qf 594 6 leukocytes leukocyte NNS cord-022526-j9kg00qf 594 7 and and CC cord-022526-j9kg00qf 594 8 endothelial endothelial JJ cord-022526-j9kg00qf 594 9 cells cell NNS cord-022526-j9kg00qf 594 10 also also RB cord-022526-j9kg00qf 594 11 affect affect VBP cord-022526-j9kg00qf 594 12 blood blood NN cord-022526-j9kg00qf 594 13 flow flow NN cord-022526-j9kg00qf 594 14 . . . cord-022526-j9kg00qf 595 1 Histamine histamine NN cord-022526-j9kg00qf 595 2 and and CC cord-022526-j9kg00qf 595 3 the the DT cord-022526-j9kg00qf 595 4 vasoactive vasoactive JJ cord-022526-j9kg00qf 595 5 lipids lipid NNS cord-022526-j9kg00qf 595 6 derived derive VBN cord-022526-j9kg00qf 595 7 from from IN cord-022526-j9kg00qf 595 8 arachidonic arachidonic JJ cord-022526-j9kg00qf 595 9 acid acid NN cord-022526-j9kg00qf 595 10 ( ( -LRB- cord-022526-j9kg00qf 595 11 leukotrienes leukotriene NNS cord-022526-j9kg00qf 595 12 , , , cord-022526-j9kg00qf 595 13 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 595 14 , , , cord-022526-j9kg00qf 595 15 thromboxane thromboxane NN cord-022526-j9kg00qf 595 16 , , , cord-022526-j9kg00qf 595 17 prostacycline prostacycline NNP cord-022526-j9kg00qf 595 18 , , , cord-022526-j9kg00qf 595 19 and and CC cord-022526-j9kg00qf 595 20 platelet platelet NN cord-022526-j9kg00qf 595 21 - - HYPH cord-022526-j9kg00qf 595 22 activating activate VBG cord-022526-j9kg00qf 595 23 factor factor NN cord-022526-j9kg00qf 595 24 ) ) -RRB- cord-022526-j9kg00qf 595 25 have have VB cord-022526-j9kg00qf 595 26 a a DT cord-022526-j9kg00qf 595 27 prominent prominent JJ cord-022526-j9kg00qf 595 28 role role NN cord-022526-j9kg00qf 595 29 in in IN cord-022526-j9kg00qf 595 30 regulating regulate VBG cord-022526-j9kg00qf 595 31 local local JJ cord-022526-j9kg00qf 595 32 perfusion perfusion NN cord-022526-j9kg00qf 595 33 during during IN cord-022526-j9kg00qf 595 34 inflammation inflammation NN cord-022526-j9kg00qf 595 35 and and CC cord-022526-j9kg00qf 595 36 also also RB cord-022526-j9kg00qf 595 37 may may MD cord-022526-j9kg00qf 595 38 have have VB cord-022526-j9kg00qf 595 39 systemic systemic JJ cord-022526-j9kg00qf 595 40 effects effect NNS cord-022526-j9kg00qf 595 41 on on IN cord-022526-j9kg00qf 595 42 blood blood NN cord-022526-j9kg00qf 595 43 flow flow NN cord-022526-j9kg00qf 595 44 . . . cord-022526-j9kg00qf 596 1 Procoagulant procoagulant JJ cord-022526-j9kg00qf 596 2 mediators mediator NNS cord-022526-j9kg00qf 596 3 released release VBN cord-022526-j9kg00qf 596 4 by by IN cord-022526-j9kg00qf 596 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 596 6 cells cell NNS cord-022526-j9kg00qf 596 7 in in IN cord-022526-j9kg00qf 596 8 response response NN cord-022526-j9kg00qf 596 9 to to IN cord-022526-j9kg00qf 596 10 the the DT cord-022526-j9kg00qf 596 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 596 12 process process NN cord-022526-j9kg00qf 596 13 ( ( -LRB- cord-022526-j9kg00qf 596 14 i.e. i.e. FW cord-022526-j9kg00qf 596 15 , , , cord-022526-j9kg00qf 596 16 tissue tissue NN cord-022526-j9kg00qf 596 17 factor factor NN cord-022526-j9kg00qf 596 18 produced produce VBN cord-022526-j9kg00qf 596 19 by by IN cord-022526-j9kg00qf 596 20 macrophages macrophage NNS cord-022526-j9kg00qf 596 21 or or CC cord-022526-j9kg00qf 596 22 endothelial endothelial JJ cord-022526-j9kg00qf 596 23 cells cell NNS cord-022526-j9kg00qf 596 24 ) ) -RRB- cord-022526-j9kg00qf 596 25 , , , cord-022526-j9kg00qf 596 26 exposed expose VBN cord-022526-j9kg00qf 596 27 basement basement NN cord-022526-j9kg00qf 596 28 membrane membrane NN cord-022526-j9kg00qf 596 29 proteins protein NNS cord-022526-j9kg00qf 596 30 , , , cord-022526-j9kg00qf 596 31 and and CC cord-022526-j9kg00qf 596 32 bacterial bacterial JJ cord-022526-j9kg00qf 596 33 components component NNS cord-022526-j9kg00qf 596 34 can can MD cord-022526-j9kg00qf 596 35 trigger trigger VB cord-022526-j9kg00qf 596 36 the the DT cord-022526-j9kg00qf 596 37 contact contact NN cord-022526-j9kg00qf 596 38 system system NN cord-022526-j9kg00qf 596 39 and and CC cord-022526-j9kg00qf 596 40 the the DT cord-022526-j9kg00qf 596 41 coagulation coagulation NN cord-022526-j9kg00qf 596 42 and and CC cord-022526-j9kg00qf 596 43 complement complement NN cord-022526-j9kg00qf 596 44 cascades cascade NNS cord-022526-j9kg00qf 596 45 , , , cord-022526-j9kg00qf 596 46 the the DT cord-022526-j9kg00qf 596 47 products product NNS cord-022526-j9kg00qf 596 48 of of IN cord-022526-j9kg00qf 596 49 which which WDT cord-022526-j9kg00qf 596 50 affect affect VBP cord-022526-j9kg00qf 596 51 blood blood NN cord-022526-j9kg00qf 596 52 flow flow NN cord-022526-j9kg00qf 596 53 . . . cord-022526-j9kg00qf 597 1 Nitric nitric NN cord-022526-j9kg00qf 597 2 oxide oxide NN cord-022526-j9kg00qf 597 3 , , , cord-022526-j9kg00qf 597 4 whether whether IN cord-022526-j9kg00qf 597 5 produced produce VBN cord-022526-j9kg00qf 597 6 by by IN cord-022526-j9kg00qf 597 7 endothelial endothelial JJ cord-022526-j9kg00qf 597 8 cells cell NNS cord-022526-j9kg00qf 597 9 or or CC cord-022526-j9kg00qf 597 10 leukocytes leukocyte NNS cord-022526-j9kg00qf 597 11 ( ( -LRB- cord-022526-j9kg00qf 597 12 macrophages macrophage NNS cord-022526-j9kg00qf 597 13 ) ) -RRB- cord-022526-j9kg00qf 597 14 , , , cord-022526-j9kg00qf 597 15 is be VBZ cord-022526-j9kg00qf 597 16 a a DT cord-022526-j9kg00qf 597 17 potent potent JJ cord-022526-j9kg00qf 597 18 regulator regulator NN cord-022526-j9kg00qf 597 19 of of IN cord-022526-j9kg00qf 597 20 blood blood NN cord-022526-j9kg00qf 597 21 flow flow NN cord-022526-j9kg00qf 597 22 and and CC cord-022526-j9kg00qf 597 23 has have VBZ cord-022526-j9kg00qf 597 24 a a DT cord-022526-j9kg00qf 597 25 significant significant JJ cord-022526-j9kg00qf 597 26 role role NN cord-022526-j9kg00qf 597 27 in in IN cord-022526-j9kg00qf 597 28 the the DT cord-022526-j9kg00qf 597 29 control control NN cord-022526-j9kg00qf 597 30 of of IN cord-022526-j9kg00qf 597 31 perfusion perfusion NN cord-022526-j9kg00qf 597 32 during during IN cord-022526-j9kg00qf 597 33 inflammation inflammation NN cord-022526-j9kg00qf 597 34 . . . cord-022526-j9kg00qf 598 1 60 60 CD cord-022526-j9kg00qf 598 2 Many many JJ cord-022526-j9kg00qf 598 3 of of IN cord-022526-j9kg00qf 598 4 the the DT cord-022526-j9kg00qf 598 5 mediators mediator NNS cord-022526-j9kg00qf 598 6 that that WDT cord-022526-j9kg00qf 598 7 affect affect VBP cord-022526-j9kg00qf 598 8 perfusion perfusion NN cord-022526-j9kg00qf 598 9 also also RB cord-022526-j9kg00qf 598 10 affect affect VBP cord-022526-j9kg00qf 598 11 endothelial endothelial JJ cord-022526-j9kg00qf 598 12 permeability permeability NN cord-022526-j9kg00qf 598 13 , , , cord-022526-j9kg00qf 598 14 altering alter VBG cord-022526-j9kg00qf 598 15 osmotic osmotic JJ cord-022526-j9kg00qf 598 16 and and CC cord-022526-j9kg00qf 598 17 hydrostatic hydrostatic JJ cord-022526-j9kg00qf 598 18 balance balance NN cord-022526-j9kg00qf 598 19 and and CC cord-022526-j9kg00qf 598 20 tissue tissue NN cord-022526-j9kg00qf 598 21 edema edema NN cord-022526-j9kg00qf 598 22 . . . cord-022526-j9kg00qf 599 1 In in IN cord-022526-j9kg00qf 599 2 extreme extreme JJ cord-022526-j9kg00qf 599 3 cases case NNS cord-022526-j9kg00qf 599 4 , , , cord-022526-j9kg00qf 599 5 local local JJ cord-022526-j9kg00qf 599 6 and and CC cord-022526-j9kg00qf 599 7 systemic systemic JJ cord-022526-j9kg00qf 599 8 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 599 9 initiated initiate VBN cord-022526-j9kg00qf 599 10 by by IN cord-022526-j9kg00qf 599 11 vascular vascular JJ cord-022526-j9kg00qf 599 12 injury injury NN cord-022526-j9kg00qf 599 13 and and CC cord-022526-j9kg00qf 599 14 absorption absorption NN cord-022526-j9kg00qf 599 15 of of IN cord-022526-j9kg00qf 599 16 microbial microbial JJ cord-022526-j9kg00qf 599 17 products product NNS cord-022526-j9kg00qf 599 18 and and CC cord-022526-j9kg00qf 599 19 inflammatory inflammatory JJ cord-022526-j9kg00qf 599 20 mediators mediator NNS cord-022526-j9kg00qf 599 21 induce induce VBP cord-022526-j9kg00qf 599 22 a a DT cord-022526-j9kg00qf 599 23 hypercoagulable hypercoagulable JJ cord-022526-j9kg00qf 599 24 state state NN cord-022526-j9kg00qf 599 25 , , , cord-022526-j9kg00qf 599 26 leading lead VBG cord-022526-j9kg00qf 599 27 to to IN cord-022526-j9kg00qf 599 28 microthrombus microthrombus NNP cord-022526-j9kg00qf 599 29 formation formation NN cord-022526-j9kg00qf 599 30 , , , cord-022526-j9kg00qf 599 31 which which WDT cord-022526-j9kg00qf 599 32 can can MD cord-022526-j9kg00qf 599 33 reduce reduce VB cord-022526-j9kg00qf 599 34 blood blood NN cord-022526-j9kg00qf 599 35 flow flow NN cord-022526-j9kg00qf 599 36 , , , cord-022526-j9kg00qf 599 37 or or CC cord-022526-j9kg00qf 599 38 macrothrombus macrothrombus NNP cord-022526-j9kg00qf 599 39 formation formation NN cord-022526-j9kg00qf 599 40 , , , cord-022526-j9kg00qf 599 41 which which WDT cord-022526-j9kg00qf 599 42 causes cause VBZ cord-022526-j9kg00qf 599 43 tissue tissue NN cord-022526-j9kg00qf 599 44 infarction infarction NN cord-022526-j9kg00qf 599 45 . . . cord-022526-j9kg00qf 600 1 The the DT cord-022526-j9kg00qf 600 2 cellular cellular JJ cord-022526-j9kg00qf 600 3 mediators mediator NNS cord-022526-j9kg00qf 600 4 of of IN cord-022526-j9kg00qf 600 5 inflammation inflammation NN cord-022526-j9kg00qf 600 6 have have VBP cord-022526-j9kg00qf 600 7 the the DT cord-022526-j9kg00qf 600 8 potential potential NN cord-022526-j9kg00qf 600 9 to to TO cord-022526-j9kg00qf 600 10 inflict inflict VB cord-022526-j9kg00qf 600 11 severe severe JJ cord-022526-j9kg00qf 600 12 injury injury NN cord-022526-j9kg00qf 600 13 to to IN cord-022526-j9kg00qf 600 14 intestinal intestinal JJ cord-022526-j9kg00qf 600 15 tissues tissue NNS cord-022526-j9kg00qf 600 16 . . . cord-022526-j9kg00qf 601 1 Neutrophils neutrophil NNS cord-022526-j9kg00qf 601 2 have have VBP cord-022526-j9kg00qf 601 3 an an DT cord-022526-j9kg00qf 601 4 important important JJ cord-022526-j9kg00qf 601 5 role role NN cord-022526-j9kg00qf 601 6 in in IN cord-022526-j9kg00qf 601 7 the the DT cord-022526-j9kg00qf 601 8 pathophysiology pathophysiology NN cord-022526-j9kg00qf 601 9 of of IN cord-022526-j9kg00qf 601 10 many many JJ cord-022526-j9kg00qf 601 11 intestinal intestinal JJ cord-022526-j9kg00qf 601 12 diseases disease NNS cord-022526-j9kg00qf 601 13 , , , cord-022526-j9kg00qf 601 14 including include VBG cord-022526-j9kg00qf 601 15 ischemia ischemia NN cord-022526-j9kg00qf 601 16 - - HYPH cord-022526-j9kg00qf 601 17 reperfusion reperfusion NN cord-022526-j9kg00qf 601 18 injury injury NN cord-022526-j9kg00qf 601 19 , , , cord-022526-j9kg00qf 601 20 16 16 CD cord-022526-j9kg00qf 601 21 , , , cord-022526-j9kg00qf 601 22 22 22 CD cord-022526-j9kg00qf 601 23 infectious infectious JJ cord-022526-j9kg00qf 601 24 enterocolitis enterocolitis NN cord-022526-j9kg00qf 601 25 , , , cord-022526-j9kg00qf 601 26 [ [ -LRB- cord-022526-j9kg00qf 601 27 23 23 CD cord-022526-j9kg00qf 601 28 ] ] -RRB- cord-022526-j9kg00qf 601 29 [ [ -LRB- cord-022526-j9kg00qf 601 30 24 24 CD cord-022526-j9kg00qf 601 31 ] ] -RRB- cord-022526-j9kg00qf 601 32 [ [ -LRB- cord-022526-j9kg00qf 601 33 25 25 CD cord-022526-j9kg00qf 601 34 ] ] -RRB- cord-022526-j9kg00qf 601 35 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 601 36 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 601 37 drug drug NN cord-022526-j9kg00qf 601 38 - - HYPH cord-022526-j9kg00qf 601 39 induced induce VBN cord-022526-j9kg00qf 601 40 mucosal mucosal JJ cord-022526-j9kg00qf 601 41 ulceration ulceration NN cord-022526-j9kg00qf 601 42 , , , cord-022526-j9kg00qf 601 43 26 26 CD cord-022526-j9kg00qf 601 44 and and CC cord-022526-j9kg00qf 601 45 others other NNS cord-022526-j9kg00qf 601 46 . . . cord-022526-j9kg00qf 602 1 Depletion depletion NN cord-022526-j9kg00qf 602 2 of of IN cord-022526-j9kg00qf 602 3 neutrophils neutrophil NNS cord-022526-j9kg00qf 602 4 , , , cord-022526-j9kg00qf 602 5 blockade blockade NN cord-022526-j9kg00qf 602 6 of of IN cord-022526-j9kg00qf 602 7 their -PRON- PRP$ cord-022526-j9kg00qf 602 8 emigration emigration NN cord-022526-j9kg00qf 602 9 into into IN cord-022526-j9kg00qf 602 10 tissues tissue NNS cord-022526-j9kg00qf 602 11 , , , cord-022526-j9kg00qf 602 12 or or CC cord-022526-j9kg00qf 602 13 inhibition inhibition NN cord-022526-j9kg00qf 602 14 of of IN cord-022526-j9kg00qf 602 15 neutrophil neutrophil NN cord-022526-j9kg00qf 602 16 activation activation NN cord-022526-j9kg00qf 602 17 reduce reduce VBP cord-022526-j9kg00qf 602 18 the the DT cord-022526-j9kg00qf 602 19 severity severity NN cord-022526-j9kg00qf 602 20 of of IN cord-022526-j9kg00qf 602 21 these these DT cord-022526-j9kg00qf 602 22 and and CC cord-022526-j9kg00qf 602 23 other other JJ cord-022526-j9kg00qf 602 24 inflammatory inflammatory JJ cord-022526-j9kg00qf 602 25 diseases disease NNS cord-022526-j9kg00qf 602 26 . . . cord-022526-j9kg00qf 603 1 61 61 CD cord-022526-j9kg00qf 604 1 Thus thus RB cord-022526-j9kg00qf 604 2 many many JJ cord-022526-j9kg00qf 604 3 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 604 4 therapies therapy NNS cord-022526-j9kg00qf 604 5 are be VBP cord-022526-j9kg00qf 604 6 emerging emerge VBG cord-022526-j9kg00qf 604 7 that that IN cord-022526-j9kg00qf 604 8 specifically specifically RB cord-022526-j9kg00qf 604 9 target target VB cord-022526-j9kg00qf 604 10 neutrophil neutrophil NN cord-022526-j9kg00qf 604 11 adhesion adhesion NN cord-022526-j9kg00qf 604 12 , , , cord-022526-j9kg00qf 604 13 migration migration NN cord-022526-j9kg00qf 604 14 , , , cord-022526-j9kg00qf 604 15 and and CC cord-022526-j9kg00qf 604 16 activation activation NN cord-022526-j9kg00qf 604 17 . . . cord-022526-j9kg00qf 605 1 Migration migration NN cord-022526-j9kg00qf 605 2 of of IN cord-022526-j9kg00qf 605 3 neutrophils neutrophil NNS cord-022526-j9kg00qf 605 4 through through IN cord-022526-j9kg00qf 605 5 endothelium endothelium NN cord-022526-j9kg00qf 605 6 during during IN cord-022526-j9kg00qf 605 7 emigration emigration NN cord-022526-j9kg00qf 605 8 into into IN cord-022526-j9kg00qf 605 9 inflamed inflamed JJ cord-022526-j9kg00qf 605 10 tissues tissue NNS cord-022526-j9kg00qf 605 11 is be VBZ cord-022526-j9kg00qf 605 12 remarkable remarkable JJ cord-022526-j9kg00qf 605 13 in in IN cord-022526-j9kg00qf 605 14 that that IN cord-022526-j9kg00qf 605 15 the the DT cord-022526-j9kg00qf 605 16 permeability permeability NN cord-022526-j9kg00qf 605 17 of of IN cord-022526-j9kg00qf 605 18 the the DT cord-022526-j9kg00qf 605 19 endothelial endothelial JJ cord-022526-j9kg00qf 605 20 monolayer monolayer NN cord-022526-j9kg00qf 605 21 is be VBZ cord-022526-j9kg00qf 605 22 preserved preserve VBN cord-022526-j9kg00qf 605 23 under under IN cord-022526-j9kg00qf 605 24 most most JJS cord-022526-j9kg00qf 605 25 circumstances circumstance NNS cord-022526-j9kg00qf 605 26 . . . cord-022526-j9kg00qf 606 1 However however RB cord-022526-j9kg00qf 606 2 , , , cord-022526-j9kg00qf 606 3 a a DT cord-022526-j9kg00qf 606 4 limit limit NN cord-022526-j9kg00qf 606 5 exists exist VBZ cord-022526-j9kg00qf 606 6 above above IN cord-022526-j9kg00qf 606 7 which which WDT cord-022526-j9kg00qf 606 8 neutrophil neutrophil NN cord-022526-j9kg00qf 606 9 migration migration NN cord-022526-j9kg00qf 606 10 alters alter VBZ cord-022526-j9kg00qf 606 11 the the DT cord-022526-j9kg00qf 606 12 permeability permeability NN cord-022526-j9kg00qf 606 13 characteristics characteristic NNS cord-022526-j9kg00qf 606 14 of of IN cord-022526-j9kg00qf 606 15 the the DT cord-022526-j9kg00qf 606 16 endothelium endothelium NN cord-022526-j9kg00qf 606 17 . . . cord-022526-j9kg00qf 607 1 The the DT cord-022526-j9kg00qf 607 2 effect effect NN cord-022526-j9kg00qf 607 3 is be VBZ cord-022526-j9kg00qf 607 4 in in IN cord-022526-j9kg00qf 607 5 part part NN cord-022526-j9kg00qf 607 6 physical physical JJ cord-022526-j9kg00qf 607 7 in in IN cord-022526-j9kg00qf 607 8 that that DT cord-022526-j9kg00qf 607 9 mere mere JJ cord-022526-j9kg00qf 607 10 movement movement NN cord-022526-j9kg00qf 607 11 of of IN cord-022526-j9kg00qf 607 12 large large JJ cord-022526-j9kg00qf 607 13 numbers number NNS cord-022526-j9kg00qf 607 14 of of IN cord-022526-j9kg00qf 607 15 neutrophils neutrophil NNS cord-022526-j9kg00qf 607 16 through through IN cord-022526-j9kg00qf 607 17 the the DT cord-022526-j9kg00qf 607 18 endothelium endothelium NN cord-022526-j9kg00qf 607 19 is be VBZ cord-022526-j9kg00qf 607 20 sufficient sufficient JJ cord-022526-j9kg00qf 607 21 to to TO cord-022526-j9kg00qf 607 22 disrupt disrupt VB cord-022526-j9kg00qf 607 23 the the DT cord-022526-j9kg00qf 607 24 tight tight JJ cord-022526-j9kg00qf 607 25 junctions junction NNS cord-022526-j9kg00qf 607 26 mechanically mechanically RB cord-022526-j9kg00qf 607 27 and and CC cord-022526-j9kg00qf 607 28 is be VBZ cord-022526-j9kg00qf 607 29 caused cause VBN cord-022526-j9kg00qf 607 30 in in IN cord-022526-j9kg00qf 607 31 part part NN cord-022526-j9kg00qf 607 32 by by IN cord-022526-j9kg00qf 607 33 toxic toxic JJ cord-022526-j9kg00qf 607 34 products product NNS cord-022526-j9kg00qf 607 35 of of IN cord-022526-j9kg00qf 607 36 neutrophils neutrophil NNS cord-022526-j9kg00qf 607 37 that that WDT cord-022526-j9kg00qf 607 38 damage damage VBP cord-022526-j9kg00qf 607 39 endothelial endothelial JJ cord-022526-j9kg00qf 607 40 cells cell NNS cord-022526-j9kg00qf 607 41 and and CC cord-022526-j9kg00qf 607 42 basement basement NN cord-022526-j9kg00qf 607 43 membranes membrane NNS cord-022526-j9kg00qf 607 44 . . . cord-022526-j9kg00qf 608 1 59 59 CD cord-022526-j9kg00qf 608 2 , , , cord-022526-j9kg00qf 608 3 62 62 CD cord-022526-j9kg00qf 608 4 Serine serine NN cord-022526-j9kg00qf 608 5 proteases protease NNS cord-022526-j9kg00qf 608 6 ( ( -LRB- cord-022526-j9kg00qf 608 7 particularly particularly RB cord-022526-j9kg00qf 608 8 elastase elastase NN cord-022526-j9kg00qf 608 9 ) ) -RRB- cord-022526-j9kg00qf 608 10 and and CC cord-022526-j9kg00qf 608 11 metalloproteinases metalloproteinase NNS cord-022526-j9kg00qf 608 12 released release VBN cord-022526-j9kg00qf 608 13 by by IN cord-022526-j9kg00qf 608 14 degranulating degranulate VBG cord-022526-j9kg00qf 608 15 neutrophils neutrophil NNS cord-022526-j9kg00qf 608 16 destroy destroy VBP cord-022526-j9kg00qf 608 17 tissue tissue NN cord-022526-j9kg00qf 608 18 matrix matrix NN cord-022526-j9kg00qf 608 19 proteins protein NNS cord-022526-j9kg00qf 608 20 and and CC cord-022526-j9kg00qf 608 21 cell cell NN cord-022526-j9kg00qf 608 22 - - HYPH cord-022526-j9kg00qf 608 23 surface surface NN cord-022526-j9kg00qf 608 24 proteins protein NNS cord-022526-j9kg00qf 608 25 that that WDT cord-022526-j9kg00qf 608 26 make make VBP cord-022526-j9kg00qf 608 27 up up RP cord-022526-j9kg00qf 608 28 endothelial endothelial JJ cord-022526-j9kg00qf 608 29 intercellular intercellular JJ cord-022526-j9kg00qf 608 30 junctions junction NNS cord-022526-j9kg00qf 608 31 . . . cord-022526-j9kg00qf 609 1 These these DT cord-022526-j9kg00qf 609 2 degradative degradative JJ cord-022526-j9kg00qf 609 3 enzymes enzyme NNS cord-022526-j9kg00qf 609 4 are be VBP cord-022526-j9kg00qf 609 5 particularly particularly RB cord-022526-j9kg00qf 609 6 damaging damaging JJ cord-022526-j9kg00qf 609 7 to to IN cord-022526-j9kg00qf 609 8 basement basement NN cord-022526-j9kg00qf 609 9 membranes membrane NNS cord-022526-j9kg00qf 609 10 and and CC cord-022526-j9kg00qf 609 11 the the DT cord-022526-j9kg00qf 609 12 cellular cellular JJ cord-022526-j9kg00qf 609 13 barriers barrier NNS cord-022526-j9kg00qf 609 14 of of IN cord-022526-j9kg00qf 609 15 the the DT cord-022526-j9kg00qf 609 16 endothelium endothelium NN cord-022526-j9kg00qf 609 17 , , , cord-022526-j9kg00qf 609 18 thus thus RB cord-022526-j9kg00qf 609 19 contributing contribute VBG cord-022526-j9kg00qf 609 20 to to IN cord-022526-j9kg00qf 609 21 vascular vascular JJ cord-022526-j9kg00qf 609 22 permeability permeability NN cord-022526-j9kg00qf 609 23 ( ( -LRB- cord-022526-j9kg00qf 609 24 and and CC cord-022526-j9kg00qf 609 25 local local JJ cord-022526-j9kg00qf 609 26 tissue tissue NN cord-022526-j9kg00qf 609 27 edema edema NN cord-022526-j9kg00qf 609 28 ) ) -RRB- cord-022526-j9kg00qf 609 29 and and CC cord-022526-j9kg00qf 609 30 thrombosis thrombosis NN cord-022526-j9kg00qf 609 31 . . . cord-022526-j9kg00qf 610 1 The the DT cord-022526-j9kg00qf 610 2 permeability permeability NN cord-022526-j9kg00qf 610 3 may may MD cord-022526-j9kg00qf 610 4 be be VB cord-022526-j9kg00qf 610 5 affected affect VBN cord-022526-j9kg00qf 610 6 to to IN cord-022526-j9kg00qf 610 7 the the DT cord-022526-j9kg00qf 610 8 extent extent NN cord-022526-j9kg00qf 610 9 that that IN cord-022526-j9kg00qf 610 10 not not RB cord-022526-j9kg00qf 610 11 only only RB cord-022526-j9kg00qf 610 12 water water NN cord-022526-j9kg00qf 610 13 but but CC cord-022526-j9kg00qf 610 14 macromolecules macromolecule NNS cord-022526-j9kg00qf 610 15 ( ( -LRB- cord-022526-j9kg00qf 610 16 albumin albumin NN cord-022526-j9kg00qf 610 17 , , , cord-022526-j9kg00qf 610 18 matrix matrix NN cord-022526-j9kg00qf 610 19 proteins protein NNS cord-022526-j9kg00qf 610 20 , , , cord-022526-j9kg00qf 610 21 complement complement NN cord-022526-j9kg00qf 610 22 , , , cord-022526-j9kg00qf 610 23 etc etc FW cord-022526-j9kg00qf 610 24 . . . cord-022526-j9kg00qf 610 25 ) ) -RRB- cord-022526-j9kg00qf 611 1 leak leak VB cord-022526-j9kg00qf 611 2 into into IN cord-022526-j9kg00qf 611 3 the the DT cord-022526-j9kg00qf 611 4 interstitium interstitium NN cord-022526-j9kg00qf 611 5 . . . cord-022526-j9kg00qf 612 1 Blockade blockade NN cord-022526-j9kg00qf 612 2 of of IN cord-022526-j9kg00qf 612 3 neutrophil neutrophil NN cord-022526-j9kg00qf 612 4 adhesion adhesion NN cord-022526-j9kg00qf 612 5 to to IN cord-022526-j9kg00qf 612 6 endothelium endothelium NN cord-022526-j9kg00qf 612 7 with with IN cord-022526-j9kg00qf 612 8 anti anti JJ cord-022526-j9kg00qf 612 9 - - JJ cord-022526-j9kg00qf 612 10 β β JJ cord-022526-j9kg00qf 612 11 2 2 CD cord-022526-j9kg00qf 612 12 integrin integrin NN cord-022526-j9kg00qf 612 13 antibodies antibody NNS cord-022526-j9kg00qf 612 14 has have VBZ cord-022526-j9kg00qf 612 15 a a DT cord-022526-j9kg00qf 612 16 sparing sparing JJ cord-022526-j9kg00qf 612 17 effect effect NN cord-022526-j9kg00qf 612 18 on on IN cord-022526-j9kg00qf 612 19 the the DT cord-022526-j9kg00qf 612 20 microvasculature microvasculature NN cord-022526-j9kg00qf 612 21 in in IN cord-022526-j9kg00qf 612 22 experimental experimental JJ cord-022526-j9kg00qf 612 23 intestinal intestinal JJ cord-022526-j9kg00qf 612 24 ischemiareperfusion ischemiareperfusion NN cord-022526-j9kg00qf 612 25 injury injury NN cord-022526-j9kg00qf 612 26 , , , cord-022526-j9kg00qf 612 27 reducing reduce VBG cord-022526-j9kg00qf 612 28 the the DT cord-022526-j9kg00qf 612 29 alterations alteration NNS cord-022526-j9kg00qf 612 30 in in IN cord-022526-j9kg00qf 612 31 vascular vascular JJ cord-022526-j9kg00qf 612 32 permeability permeability NN cord-022526-j9kg00qf 612 33 and and CC cord-022526-j9kg00qf 612 34 histopathologic histopathologic JJ cord-022526-j9kg00qf 612 35 evidence evidence NN cord-022526-j9kg00qf 612 36 of of IN cord-022526-j9kg00qf 612 37 microvascular microvascular JJ cord-022526-j9kg00qf 612 38 damage damage NN cord-022526-j9kg00qf 612 39 . . . cord-022526-j9kg00qf 613 1 59 59 CD cord-022526-j9kg00qf 614 1 Similar similar JJ cord-022526-j9kg00qf 614 2 to to IN cord-022526-j9kg00qf 614 3 the the DT cord-022526-j9kg00qf 614 4 endothelium endothelium NN cord-022526-j9kg00qf 614 5 of of IN cord-022526-j9kg00qf 614 6 inflamed inflamed JJ cord-022526-j9kg00qf 614 7 tissues tissue NNS cord-022526-j9kg00qf 614 8 , , , cord-022526-j9kg00qf 614 9 massive massive JJ cord-022526-j9kg00qf 614 10 neutrophil neutrophil NN cord-022526-j9kg00qf 614 11 transmigration transmigration NN cord-022526-j9kg00qf 614 12 occurs occur VBZ cord-022526-j9kg00qf 614 13 across across IN cord-022526-j9kg00qf 614 14 the the DT cord-022526-j9kg00qf 614 15 epithelium epithelium NN cord-022526-j9kg00qf 614 16 in in IN cord-022526-j9kg00qf 614 17 response response NN cord-022526-j9kg00qf 614 18 to to IN cord-022526-j9kg00qf 614 19 infection infection NN cord-022526-j9kg00qf 614 20 or or CC cord-022526-j9kg00qf 614 21 injury injury NN cord-022526-j9kg00qf 614 22 . . . cord-022526-j9kg00qf 615 1 Neutrophil Neutrophil NNP cord-022526-j9kg00qf 615 2 transepithelial transepithelial JJ cord-022526-j9kg00qf 615 3 migration migration NN cord-022526-j9kg00qf 615 4 increases increase VBZ cord-022526-j9kg00qf 615 5 epithelial epithelial JJ cord-022526-j9kg00qf 615 6 permeability permeability NN cord-022526-j9kg00qf 615 7 by by IN cord-022526-j9kg00qf 615 8 disrupting disrupt VBG cord-022526-j9kg00qf 615 9 tight tight JJ cord-022526-j9kg00qf 615 10 junctions junction NNS cord-022526-j9kg00qf 615 11 . . . cord-022526-j9kg00qf 616 1 62 62 CD cord-022526-j9kg00qf 617 1 Like like IN cord-022526-j9kg00qf 617 2 the the DT cord-022526-j9kg00qf 617 3 endothelium endothelium NN cord-022526-j9kg00qf 617 4 , , , cord-022526-j9kg00qf 617 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 617 6 disrupt disrupt VBP cord-022526-j9kg00qf 617 7 the the DT cord-022526-j9kg00qf 617 8 epithelial epithelial JJ cord-022526-j9kg00qf 617 9 barrier barrier NN cord-022526-j9kg00qf 617 10 mechanically mechanically RB cord-022526-j9kg00qf 617 11 as as IN cord-022526-j9kg00qf 617 12 they -PRON- PRP cord-022526-j9kg00qf 617 13 migrate migrate VBP cord-022526-j9kg00qf 617 14 through through IN cord-022526-j9kg00qf 617 15 ( ( -LRB- cord-022526-j9kg00qf 617 16 see see VB cord-022526-j9kg00qf 617 17 Figure Figure NNP cord-022526-j9kg00qf 617 18 13 13 CD cord-022526-j9kg00qf 617 19 .2 .2 CD cord-022526-j9kg00qf 617 20 - - SYM cord-022526-j9kg00qf 617 21 1 1 CD cord-022526-j9kg00qf 617 22 ) ) -RRB- cord-022526-j9kg00qf 617 23 . . . cord-022526-j9kg00qf 618 1 Proteases protease NNS cord-022526-j9kg00qf 618 2 , , , cord-022526-j9kg00qf 618 3 particularly particularly RB cord-022526-j9kg00qf 618 4 elastase elastase NN cord-022526-j9kg00qf 618 5 , , , cord-022526-j9kg00qf 618 6 degrade degrade VBP cord-022526-j9kg00qf 618 7 basement basement NN cord-022526-j9kg00qf 618 8 membrane membrane NN cord-022526-j9kg00qf 618 9 components component NNS cord-022526-j9kg00qf 618 10 and and CC cord-022526-j9kg00qf 618 11 tight tight JJ cord-022526-j9kg00qf 618 12 junction junction NN cord-022526-j9kg00qf 618 13 proteins protein NNS cord-022526-j9kg00qf 618 14 . . . cord-022526-j9kg00qf 619 1 Products product NNS cord-022526-j9kg00qf 619 2 of of IN cord-022526-j9kg00qf 619 3 activated activate VBN cord-022526-j9kg00qf 619 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 619 5 ( ( -LRB- cord-022526-j9kg00qf 619 6 TNF TNF NNP cord-022526-j9kg00qf 619 7 - - HYPH cord-022526-j9kg00qf 619 8 α α NNP cord-022526-j9kg00qf 619 9 and and CC cord-022526-j9kg00qf 619 10 interferon interferon NN cord-022526-j9kg00qf 619 11 - - HYPH cord-022526-j9kg00qf 619 12 γ γ NN cord-022526-j9kg00qf 619 13 ) ) -RRB- cord-022526-j9kg00qf 619 14 increase increase VB cord-022526-j9kg00qf 619 15 tight tight JJ cord-022526-j9kg00qf 619 16 junction junction NN cord-022526-j9kg00qf 619 17 permeability permeability NN cord-022526-j9kg00qf 619 18 by by IN cord-022526-j9kg00qf 619 19 direct direct JJ cord-022526-j9kg00qf 619 20 effects effect NNS cord-022526-j9kg00qf 619 21 on on IN cord-022526-j9kg00qf 619 22 the the DT cord-022526-j9kg00qf 619 23 enterocytes enterocyte NNS cord-022526-j9kg00qf 619 24 . . . cord-022526-j9kg00qf 620 1 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 620 2 released release VBN cord-022526-j9kg00qf 620 3 by by IN cord-022526-j9kg00qf 620 4 activated activate VBN cord-022526-j9kg00qf 620 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 620 6 stimulate stimulate VBP cord-022526-j9kg00qf 620 7 epithelial epithelial JJ cord-022526-j9kg00qf 620 8 secretion secretion NN cord-022526-j9kg00qf 620 9 , , , cord-022526-j9kg00qf 620 10 thus thus RB cord-022526-j9kg00qf 620 11 contributing contribute VBG cord-022526-j9kg00qf 620 12 to to IN cord-022526-j9kg00qf 620 13 diarrhea diarrhea NN cord-022526-j9kg00qf 620 14 . . . cord-022526-j9kg00qf 621 1 Subepithelial subepithelial JJ cord-022526-j9kg00qf 621 2 accumulation accumulation NN cord-022526-j9kg00qf 621 3 of of IN cord-022526-j9kg00qf 621 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 621 5 can can MD cord-022526-j9kg00qf 621 6 lead lead VB cord-022526-j9kg00qf 621 7 to to IN cord-022526-j9kg00qf 621 8 deadhesion deadhesion NN cord-022526-j9kg00qf 621 9 of of IN cord-022526-j9kg00qf 621 10 the the DT cord-022526-j9kg00qf 621 11 epithelial epithelial JJ cord-022526-j9kg00qf 621 12 cells cell NNS cord-022526-j9kg00qf 621 13 from from IN cord-022526-j9kg00qf 621 14 the the DT cord-022526-j9kg00qf 621 15 basement basement NN cord-022526-j9kg00qf 621 16 membrane membrane NN cord-022526-j9kg00qf 621 17 and and CC cord-022526-j9kg00qf 621 18 mild mild JJ cord-022526-j9kg00qf 621 19 to to IN cord-022526-j9kg00qf 621 20 severe severe JJ cord-022526-j9kg00qf 621 21 ulceration ulceration NN cord-022526-j9kg00qf 621 22 . . . cord-022526-j9kg00qf 622 1 The the DT cord-022526-j9kg00qf 622 2 physiologic physiologic JJ cord-022526-j9kg00qf 622 3 results result NNS cord-022526-j9kg00qf 622 4 of of IN cord-022526-j9kg00qf 622 5 the the DT cord-022526-j9kg00qf 622 6 effects effect NNS cord-022526-j9kg00qf 622 7 of of IN cord-022526-j9kg00qf 622 8 neutrophils neutrophil NNS cord-022526-j9kg00qf 622 9 and and CC cord-022526-j9kg00qf 622 10 their -PRON- PRP$ cord-022526-j9kg00qf 622 11 products product NNS cord-022526-j9kg00qf 622 12 on on IN cord-022526-j9kg00qf 622 13 the the DT cord-022526-j9kg00qf 622 14 epithelial epithelial JJ cord-022526-j9kg00qf 622 15 barrier barrier NN cord-022526-j9kg00qf 622 16 include include VBP cord-022526-j9kg00qf 622 17 protein protein NN cord-022526-j9kg00qf 622 18 - - HYPH cord-022526-j9kg00qf 622 19 losing lose VBG cord-022526-j9kg00qf 622 20 enteropathy enteropathy NN cord-022526-j9kg00qf 622 21 and and CC cord-022526-j9kg00qf 622 22 absorption absorption NN cord-022526-j9kg00qf 622 23 of of IN cord-022526-j9kg00qf 622 24 bacterial bacterial JJ cord-022526-j9kg00qf 622 25 cell cell NN cord-022526-j9kg00qf 622 26 wall wall NN cord-022526-j9kg00qf 622 27 constituents constituent NNS cord-022526-j9kg00qf 622 28 , , , cord-022526-j9kg00qf 622 29 which which WDT cord-022526-j9kg00qf 622 30 potentiates potentiate VBZ cord-022526-j9kg00qf 622 31 the the DT cord-022526-j9kg00qf 622 32 local local JJ cord-022526-j9kg00qf 622 33 and and CC cord-022526-j9kg00qf 622 34 systemic systemic JJ cord-022526-j9kg00qf 622 35 inflammatory inflammatory JJ cord-022526-j9kg00qf 622 36 responses response NNS cord-022526-j9kg00qf 622 37 . . . cord-022526-j9kg00qf 623 1 Neutrophils neutrophils NN cord-022526-j9kg00qf 623 2 in in IN cord-022526-j9kg00qf 623 3 inflamed inflamed JJ cord-022526-j9kg00qf 623 4 tissues tissue NNS cord-022526-j9kg00qf 623 5 stimulated stimulate VBN cord-022526-j9kg00qf 623 6 by by IN cord-022526-j9kg00qf 623 7 potent potent JJ cord-022526-j9kg00qf 623 8 host host NN cord-022526-j9kg00qf 623 9 - - HYPH cord-022526-j9kg00qf 623 10 derived derive VBN cord-022526-j9kg00qf 623 11 activators activator NNS cord-022526-j9kg00qf 623 12 ( ( -LRB- cord-022526-j9kg00qf 623 13 such such JJ cord-022526-j9kg00qf 623 14 as as IN cord-022526-j9kg00qf 623 15 IL-1β IL-1β NNP cord-022526-j9kg00qf 623 16 and and CC cord-022526-j9kg00qf 623 17 TNF TNF NNP cord-022526-j9kg00qf 623 18 - - HYPH cord-022526-j9kg00qf 623 19 α α NNP cord-022526-j9kg00qf 623 20 ) ) -RRB- cord-022526-j9kg00qf 623 21 and and CC cord-022526-j9kg00qf 623 22 bacterial bacterial JJ cord-022526-j9kg00qf 623 23 products product NNS cord-022526-j9kg00qf 623 24 ( ( -LRB- cord-022526-j9kg00qf 623 25 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 623 26 ) ) -RRB- cord-022526-j9kg00qf 623 27 release release VBP cord-022526-j9kg00qf 623 28 copious copious JJ cord-022526-j9kg00qf 623 29 amounts amount NNS cord-022526-j9kg00qf 623 30 of of IN cord-022526-j9kg00qf 623 31 ROIs roi NNS cord-022526-j9kg00qf 623 32 ( ( -LRB- cord-022526-j9kg00qf 623 33 see see VB cord-022526-j9kg00qf 623 34 Figure Figure NNP cord-022526-j9kg00qf 623 35 13 13 CD cord-022526-j9kg00qf 623 36 .2 .2 CD cord-022526-j9kg00qf 623 37 - - SYM cord-022526-j9kg00qf 623 38 1 1 CD cord-022526-j9kg00qf 623 39 ) ) -RRB- cord-022526-j9kg00qf 623 40 . . . cord-022526-j9kg00qf 624 1 Although although IN cord-022526-j9kg00qf 624 2 these these DT cord-022526-j9kg00qf 624 3 oxygen oxygen NN cord-022526-j9kg00qf 624 4 and and CC cord-022526-j9kg00qf 624 5 oxyhalide oxyhalide JJ cord-022526-j9kg00qf 624 6 radicals radical NNS cord-022526-j9kg00qf 624 7 are be VBP cord-022526-j9kg00qf 624 8 important important JJ cord-022526-j9kg00qf 624 9 for for IN cord-022526-j9kg00qf 624 10 killing kill VBG cord-022526-j9kg00qf 624 11 pathogens pathogen NNS cord-022526-j9kg00qf 624 12 , , , cord-022526-j9kg00qf 624 13 they -PRON- PRP cord-022526-j9kg00qf 624 14 are be VBP cord-022526-j9kg00qf 624 15 also also RB cord-022526-j9kg00qf 624 16 potentially potentially RB cord-022526-j9kg00qf 624 17 toxic toxic JJ cord-022526-j9kg00qf 624 18 to to TO cord-022526-j9kg00qf 624 19 epithelial epithelial JJ cord-022526-j9kg00qf 624 20 and and CC cord-022526-j9kg00qf 624 21 endothelial endothelial JJ cord-022526-j9kg00qf 624 22 cells cell NNS cord-022526-j9kg00qf 624 23 and and CC cord-022526-j9kg00qf 624 24 matrix matrix NN cord-022526-j9kg00qf 624 25 proteins protein NNS cord-022526-j9kg00qf 624 26 . . . cord-022526-j9kg00qf 625 1 Reactive reactive JJ cord-022526-j9kg00qf 625 2 nitrogen nitrogen NN cord-022526-j9kg00qf 625 3 intermediates intermediate NNS cord-022526-j9kg00qf 625 4 produced produce VBN cord-022526-j9kg00qf 625 5 primarily primarily RB cord-022526-j9kg00qf 625 6 by by IN cord-022526-j9kg00qf 625 7 macrophages macrophage NNS cord-022526-j9kg00qf 625 8 during during IN cord-022526-j9kg00qf 625 9 inflammation inflammation NN cord-022526-j9kg00qf 625 10 combine combine VBP cord-022526-j9kg00qf 625 11 with with IN cord-022526-j9kg00qf 625 12 ROIs roi NNS cord-022526-j9kg00qf 625 13 to to TO cord-022526-j9kg00qf 625 14 form form VB cord-022526-j9kg00qf 625 15 peroxynitrites peroxynitrite NNS cord-022526-j9kg00qf 625 16 , , , cord-022526-j9kg00qf 625 17 which which WDT cord-022526-j9kg00qf 625 18 are be VBP cord-022526-j9kg00qf 625 19 particularly particularly RB cord-022526-j9kg00qf 625 20 toxic toxic JJ cord-022526-j9kg00qf 625 21 . . . cord-022526-j9kg00qf 626 1 11 11 CD cord-022526-j9kg00qf 627 1 In in IN cord-022526-j9kg00qf 627 2 addition addition NN cord-022526-j9kg00qf 627 3 to to IN cord-022526-j9kg00qf 627 4 injury injury NN cord-022526-j9kg00qf 627 5 to to IN cord-022526-j9kg00qf 627 6 mucosal mucosal JJ cord-022526-j9kg00qf 627 7 tissues tissue NNS cord-022526-j9kg00qf 627 8 , , , cord-022526-j9kg00qf 627 9 ROIs roi NNS cord-022526-j9kg00qf 627 10 also also RB cord-022526-j9kg00qf 627 11 have have VBP cord-022526-j9kg00qf 627 12 an an DT cord-022526-j9kg00qf 627 13 as as IN cord-022526-j9kg00qf 627 14 yet yet RB cord-022526-j9kg00qf 627 15 ill ill RB cord-022526-j9kg00qf 627 16 - - HYPH cord-022526-j9kg00qf 627 17 defined define VBN cord-022526-j9kg00qf 627 18 role role NN cord-022526-j9kg00qf 627 19 in in IN cord-022526-j9kg00qf 627 20 recruiting recruit VBG cord-022526-j9kg00qf 627 21 and and CC cord-022526-j9kg00qf 627 22 activating activate VBG cord-022526-j9kg00qf 627 23 neutrophils neutrophil NNS cord-022526-j9kg00qf 627 24 , , , cord-022526-j9kg00qf 627 25 thereby thereby RB cord-022526-j9kg00qf 627 26 potentiating potentiate VBG cord-022526-j9kg00qf 627 27 the the DT cord-022526-j9kg00qf 627 28 inflammatory inflammatory JJ cord-022526-j9kg00qf 627 29 response response NN cord-022526-j9kg00qf 627 30 . . . cord-022526-j9kg00qf 628 1 63 63 CD cord-022526-j9kg00qf 629 1 In in IN cord-022526-j9kg00qf 629 2 support support NN cord-022526-j9kg00qf 629 3 of of IN cord-022526-j9kg00qf 629 4 the the DT cord-022526-j9kg00qf 629 5 role role NN cord-022526-j9kg00qf 629 6 of of IN cord-022526-j9kg00qf 629 7 ROIs roi NNS cord-022526-j9kg00qf 629 8 in in IN cord-022526-j9kg00qf 629 9 inflammatory inflammatory JJ cord-022526-j9kg00qf 629 10 diseases disease NNS cord-022526-j9kg00qf 629 11 of of IN cord-022526-j9kg00qf 629 12 the the DT cord-022526-j9kg00qf 629 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 629 14 tract tract NN cord-022526-j9kg00qf 629 15 , , , cord-022526-j9kg00qf 629 16 administration administration NN cord-022526-j9kg00qf 629 17 of of IN cord-022526-j9kg00qf 629 18 inhibitors inhibitor NNS cord-022526-j9kg00qf 629 19 of of IN cord-022526-j9kg00qf 629 20 ROI ROI NNP cord-022526-j9kg00qf 629 21 production production NN cord-022526-j9kg00qf 629 22 or or CC cord-022526-j9kg00qf 629 23 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 629 24 ROI ROI NNP cord-022526-j9kg00qf 629 25 scavengers scavenger NNS cord-022526-j9kg00qf 629 26 can can MD cord-022526-j9kg00qf 629 27 be be VB cord-022526-j9kg00qf 629 28 protective protective JJ cord-022526-j9kg00qf 629 29 in in IN cord-022526-j9kg00qf 629 30 many many JJ cord-022526-j9kg00qf 629 31 models model NNS cord-022526-j9kg00qf 629 32 of of IN cord-022526-j9kg00qf 629 33 reperfusion reperfusion NN cord-022526-j9kg00qf 629 34 injury injury NN cord-022526-j9kg00qf 629 35 or or CC cord-022526-j9kg00qf 629 36 enterocolitis enterocolitis NN cord-022526-j9kg00qf 629 37 . . . cord-022526-j9kg00qf 630 1 Many many JJ cord-022526-j9kg00qf 630 2 therapies therapy NNS cord-022526-j9kg00qf 630 3 are be VBP cord-022526-j9kg00qf 630 4 aimed aim VBN cord-022526-j9kg00qf 630 5 at at IN cord-022526-j9kg00qf 630 6 inhibiting inhibit VBG cord-022526-j9kg00qf 630 7 neutrophil neutrophil NN cord-022526-j9kg00qf 630 8 activation activation NN cord-022526-j9kg00qf 630 9 and and CC cord-022526-j9kg00qf 630 10 effector effector NN cord-022526-j9kg00qf 630 11 functions function NNS cord-022526-j9kg00qf 630 12 in in IN cord-022526-j9kg00qf 630 13 tissues tissue NNS cord-022526-j9kg00qf 630 14 have have VBP cord-022526-j9kg00qf 630 15 been be VBN cord-022526-j9kg00qf 630 16 evaluated evaluate VBN cord-022526-j9kg00qf 630 17 for for IN cord-022526-j9kg00qf 630 18 use use NN cord-022526-j9kg00qf 630 19 in in IN cord-022526-j9kg00qf 630 20 intestinal intestinal JJ cord-022526-j9kg00qf 630 21 diseases disease NNS cord-022526-j9kg00qf 630 22 . . . cord-022526-j9kg00qf 631 1 Phosphodiesterase Phosphodiesterase NNP cord-022526-j9kg00qf 631 2 inhibitors inhibitor NNS cord-022526-j9kg00qf 631 3 , , , cord-022526-j9kg00qf 631 4 by by IN cord-022526-j9kg00qf 631 5 causing cause VBG cord-022526-j9kg00qf 631 6 cyclic cyclic JJ cord-022526-j9kg00qf 631 7 adenosine adenosine NN cord-022526-j9kg00qf 631 8 monophosphate monophosphate NN cord-022526-j9kg00qf 631 9 accumulation accumulation NN cord-022526-j9kg00qf 631 10 in in IN cord-022526-j9kg00qf 631 11 neutrophils neutrophil NNS cord-022526-j9kg00qf 631 12 , , , cord-022526-j9kg00qf 631 13 are be VBP cord-022526-j9kg00qf 631 14 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 631 15 by by IN cord-022526-j9kg00qf 631 16 virtue virtue NN cord-022526-j9kg00qf 631 17 of of IN cord-022526-j9kg00qf 631 18 their -PRON- PRP$ cord-022526-j9kg00qf 631 19 ability ability NN cord-022526-j9kg00qf 631 20 to to TO cord-022526-j9kg00qf 631 21 suppress suppress VB cord-022526-j9kg00qf 631 22 neutrophil neutrophil NN cord-022526-j9kg00qf 631 23 activation activation NN cord-022526-j9kg00qf 631 24 and and CC cord-022526-j9kg00qf 631 25 ROI ROI NNP cord-022526-j9kg00qf 631 26 production production NN cord-022526-j9kg00qf 631 27 . . . cord-022526-j9kg00qf 632 1 New new JJ cord-022526-j9kg00qf 632 2 phosphodiesterase phosphodiesterase NN cord-022526-j9kg00qf 632 3 inhibitors inhibitor NNS cord-022526-j9kg00qf 632 4 selective selective JJ cord-022526-j9kg00qf 632 5 for for IN cord-022526-j9kg00qf 632 6 the the DT cord-022526-j9kg00qf 632 7 predominant predominant JJ cord-022526-j9kg00qf 632 8 neutrophil neutrophil NN cord-022526-j9kg00qf 632 9 isoform isoform NN cord-022526-j9kg00qf 632 10 of of IN cord-022526-j9kg00qf 632 11 phosphodiesterase phosphodiesterase NN cord-022526-j9kg00qf 632 12 hold hold VBP cord-022526-j9kg00qf 632 13 promise promise NN cord-022526-j9kg00qf 632 14 for for IN cord-022526-j9kg00qf 632 15 use use NN cord-022526-j9kg00qf 632 16 in in IN cord-022526-j9kg00qf 632 17 many many JJ cord-022526-j9kg00qf 632 18 inflammatory inflammatory JJ cord-022526-j9kg00qf 632 19 diseases disease NNS cord-022526-j9kg00qf 632 20 . . . cord-022526-j9kg00qf 633 1 Subepithelial subepithelial JJ cord-022526-j9kg00qf 633 2 mast mast NN cord-022526-j9kg00qf 633 3 cells cell NNS cord-022526-j9kg00qf 633 4 also also RB cord-022526-j9kg00qf 633 5 have have VBP cord-022526-j9kg00qf 633 6 an an DT cord-022526-j9kg00qf 633 7 important important JJ cord-022526-j9kg00qf 633 8 role role NN cord-022526-j9kg00qf 633 9 in in IN cord-022526-j9kg00qf 633 10 altering alter VBG cord-022526-j9kg00qf 633 11 epithelial epithelial JJ cord-022526-j9kg00qf 633 12 permeability permeability NN cord-022526-j9kg00qf 633 13 in in IN cord-022526-j9kg00qf 633 14 inflamed inflamed JJ cord-022526-j9kg00qf 633 15 intestine intestine NN cord-022526-j9kg00qf 633 16 . . . cord-022526-j9kg00qf 634 1 During during IN cord-022526-j9kg00qf 634 2 the the DT cord-022526-j9kg00qf 634 3 intestinal intestinal JJ cord-022526-j9kg00qf 634 4 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 634 5 response response NN cord-022526-j9kg00qf 634 6 , , , cord-022526-j9kg00qf 634 7 subepithelial subepithelial JJ cord-022526-j9kg00qf 634 8 mast mast NN cord-022526-j9kg00qf 634 9 cell cell NN cord-022526-j9kg00qf 634 10 release release NN cord-022526-j9kg00qf 634 11 of of IN cord-022526-j9kg00qf 634 12 mast mast JJ cord-022526-j9kg00qf 634 13 cell cell NN cord-022526-j9kg00qf 634 14 protease protease NN cord-022526-j9kg00qf 634 15 II II NNP cord-022526-j9kg00qf 634 16 by by IN cord-022526-j9kg00qf 634 17 degranulation degranulation NN cord-022526-j9kg00qf 634 18 increases increase VBZ cord-022526-j9kg00qf 634 19 epithelial epithelial JJ cord-022526-j9kg00qf 634 20 permeability permeability NN cord-022526-j9kg00qf 634 21 via via IN cord-022526-j9kg00qf 634 22 an an DT cord-022526-j9kg00qf 634 23 effect effect NN cord-022526-j9kg00qf 634 24 on on IN cord-022526-j9kg00qf 634 25 tight tight JJ cord-022526-j9kg00qf 634 26 junctions junction NNS cord-022526-j9kg00qf 634 27 . . . cord-022526-j9kg00qf 635 1 41 41 CD cord-022526-j9kg00qf 635 2 , , , cord-022526-j9kg00qf 635 3 64 64 CD cord-022526-j9kg00qf 635 4 , , , cord-022526-j9kg00qf 635 5 65 65 CD cord-022526-j9kg00qf 636 1 This this DT cord-022526-j9kg00qf 636 2 alteration alteration NN cord-022526-j9kg00qf 636 3 in in IN cord-022526-j9kg00qf 636 4 tight tight JJ cord-022526-j9kg00qf 636 5 junction junction NN cord-022526-j9kg00qf 636 6 permeability permeability NN cord-022526-j9kg00qf 636 7 results result VBZ cord-022526-j9kg00qf 636 8 in in IN cord-022526-j9kg00qf 636 9 enhanced enhance VBN cord-022526-j9kg00qf 636 10 transepithelial transepithelial JJ cord-022526-j9kg00qf 636 11 flux flux NN cord-022526-j9kg00qf 636 12 of of IN cord-022526-j9kg00qf 636 13 macromolecules macromolecule NNS cord-022526-j9kg00qf 636 14 , , , cord-022526-j9kg00qf 636 15 including include VBG cord-022526-j9kg00qf 636 16 proteins protein NNS cord-022526-j9kg00qf 636 17 and and CC cord-022526-j9kg00qf 636 18 bacterial bacterial JJ cord-022526-j9kg00qf 636 19 products product NNS cord-022526-j9kg00qf 636 20 . . . cord-022526-j9kg00qf 637 1 Cytokines cytokine NNS cord-022526-j9kg00qf 637 2 released release VBN cord-022526-j9kg00qf 637 3 by by IN cord-022526-j9kg00qf 637 4 mast mast NN cord-022526-j9kg00qf 637 5 cells cell NNS cord-022526-j9kg00qf 637 6 and and CC cord-022526-j9kg00qf 637 7 phagocytes phagocyte NNS cord-022526-j9kg00qf 637 8 also also RB cord-022526-j9kg00qf 637 9 regulate regulate VBP cord-022526-j9kg00qf 637 10 tight tight JJ cord-022526-j9kg00qf 637 11 junction junction NN cord-022526-j9kg00qf 637 12 permeability permeability NN cord-022526-j9kg00qf 637 13 . . . cord-022526-j9kg00qf 638 1 Interleukin-4 Interleukin-4 NNP cord-022526-j9kg00qf 638 2 , , , cord-022526-j9kg00qf 638 3 a a DT cord-022526-j9kg00qf 638 4 product product NN cord-022526-j9kg00qf 638 5 of of IN cord-022526-j9kg00qf 638 6 mast mast NN cord-022526-j9kg00qf 638 7 cells cell NNS cord-022526-j9kg00qf 638 8 and and CC cord-022526-j9kg00qf 638 9 macrophages macrophage NNS cord-022526-j9kg00qf 638 10 , , , cord-022526-j9kg00qf 638 11 increases increase VBZ cord-022526-j9kg00qf 638 12 epithelial epithelial JJ cord-022526-j9kg00qf 638 13 permeability permeability NN cord-022526-j9kg00qf 638 14 . . . cord-022526-j9kg00qf 639 1 66 66 CD cord-022526-j9kg00qf 640 1 Moreover moreover RB cord-022526-j9kg00qf 640 2 , , , cord-022526-j9kg00qf 640 3 TNF TNF NNP cord-022526-j9kg00qf 640 4 - - HYPH cord-022526-j9kg00qf 640 5 α α NNP cord-022526-j9kg00qf 640 6 and and CC cord-022526-j9kg00qf 640 7 interferon interferon NN cord-022526-j9kg00qf 640 8 - - HYPH cord-022526-j9kg00qf 640 9 γ γ NN cord-022526-j9kg00qf 640 10 , , , cord-022526-j9kg00qf 640 11 products product NNS cord-022526-j9kg00qf 640 12 of of IN cord-022526-j9kg00qf 640 13 many many JJ cord-022526-j9kg00qf 640 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 640 15 cells cell NNS cord-022526-j9kg00qf 640 16 , , , cord-022526-j9kg00qf 640 17 synergistically synergistically RB cord-022526-j9kg00qf 640 18 increase increase VB cord-022526-j9kg00qf 640 19 tight tight JJ cord-022526-j9kg00qf 640 20 junction junction NN cord-022526-j9kg00qf 640 21 permeability permeability NN cord-022526-j9kg00qf 640 22 . . . cord-022526-j9kg00qf 641 1 67 67 CD cord-022526-j9kg00qf 641 2 _SP cord-022526-j9kg00qf 642 1 Acute acute JJ cord-022526-j9kg00qf 642 2 equine equine JJ cord-022526-j9kg00qf 642 3 colitis colitis NN cord-022526-j9kg00qf 642 4 causes cause VBZ cord-022526-j9kg00qf 642 5 rapid rapid JJ cord-022526-j9kg00qf 642 6 , , , cord-022526-j9kg00qf 642 7 severe severe JJ cord-022526-j9kg00qf 642 8 debilitation debilitation NN cord-022526-j9kg00qf 642 9 and and CC cord-022526-j9kg00qf 642 10 death death NN cord-022526-j9kg00qf 642 11 in in IN cord-022526-j9kg00qf 642 12 horses horse NNS cord-022526-j9kg00qf 642 13 ( ( -LRB- cord-022526-j9kg00qf 642 14 more more JJR cord-022526-j9kg00qf 642 15 than than IN cord-022526-j9kg00qf 642 16 90 90 CD cord-022526-j9kg00qf 642 17 % % NN cord-022526-j9kg00qf 642 18 of of IN cord-022526-j9kg00qf 642 19 untreated untreated JJ cord-022526-j9kg00qf 642 20 horses horse NNS cord-022526-j9kg00qf 642 21 die die VBP cord-022526-j9kg00qf 642 22 or or CC cord-022526-j9kg00qf 642 23 require require VBP cord-022526-j9kg00qf 642 24 euthanasia euthanasia NN cord-022526-j9kg00qf 642 25 ) ) -RRB- cord-022526-j9kg00qf 642 26 . . . cord-022526-j9kg00qf 643 1 1 1 LS cord-022526-j9kg00qf 644 1 Since since IN cord-022526-j9kg00qf 644 2 1919 1919 CD cord-022526-j9kg00qf 644 3 , , , cord-022526-j9kg00qf 644 4 several several JJ cord-022526-j9kg00qf 644 5 reports report NNS cord-022526-j9kg00qf 644 6 have have VBP cord-022526-j9kg00qf 644 7 described describe VBN cord-022526-j9kg00qf 644 8 a a DT cord-022526-j9kg00qf 644 9 number number NN cord-022526-j9kg00qf 644 10 of of IN cord-022526-j9kg00qf 644 11 different different JJ cord-022526-j9kg00qf 644 12 acute acute JJ cord-022526-j9kg00qf 644 13 diarrheal diarrheal JJ cord-022526-j9kg00qf 644 14 conditions condition NNS cord-022526-j9kg00qf 644 15 in in IN cord-022526-j9kg00qf 644 16 the the DT cord-022526-j9kg00qf 644 17 horse horse NN cord-022526-j9kg00qf 644 18 that that WDT cord-022526-j9kg00qf 644 19 appear appear VBP cord-022526-j9kg00qf 644 20 to to TO cord-022526-j9kg00qf 644 21 share share VB cord-022526-j9kg00qf 644 22 a a DT cord-022526-j9kg00qf 644 23 common common JJ cord-022526-j9kg00qf 644 24 characteristic characteristic JJ cord-022526-j9kg00qf 644 25 clinical clinical JJ cord-022526-j9kg00qf 644 26 presentation presentation NN cord-022526-j9kg00qf 644 27 . . . cord-022526-j9kg00qf 645 1 2 2 LS cord-022526-j9kg00qf 645 2 - - SYM cord-022526-j9kg00qf 645 3 10 10 CD cord-022526-j9kg00qf 645 4 Diarrhea diarrhea NN cord-022526-j9kg00qf 645 5 associated associate VBN cord-022526-j9kg00qf 645 6 with with IN cord-022526-j9kg00qf 645 7 acute acute JJ cord-022526-j9kg00qf 645 8 equine equine JJ cord-022526-j9kg00qf 645 9 colitis colitis NN cord-022526-j9kg00qf 645 10 occurs occur VBZ cord-022526-j9kg00qf 645 11 sporadically sporadically RB cord-022526-j9kg00qf 645 12 , , , cord-022526-j9kg00qf 645 13 is be VBZ cord-022526-j9kg00qf 645 14 highly highly RB cord-022526-j9kg00qf 645 15 fatal fatal JJ cord-022526-j9kg00qf 645 16 , , , cord-022526-j9kg00qf 645 17 and and CC cord-022526-j9kg00qf 645 18 is be VBZ cord-022526-j9kg00qf 645 19 characterized characterize VBN cord-022526-j9kg00qf 645 20 by by IN cord-022526-j9kg00qf 645 21 intraluminal intraluminal JJ cord-022526-j9kg00qf 645 22 sequestration sequestration NN cord-022526-j9kg00qf 645 23 of of IN cord-022526-j9kg00qf 645 24 fluid fluid NN cord-022526-j9kg00qf 645 25 , , , cord-022526-j9kg00qf 645 26 moderate moderate JJ cord-022526-j9kg00qf 645 27 to to IN cord-022526-j9kg00qf 645 28 severe severe JJ cord-022526-j9kg00qf 645 29 colic colic NN cord-022526-j9kg00qf 645 30 ( ( -LRB- cord-022526-j9kg00qf 645 31 abdominal abdominal JJ cord-022526-j9kg00qf 645 32 pain pain NN cord-022526-j9kg00qf 645 33 ) ) -RRB- cord-022526-j9kg00qf 645 34 , , , cord-022526-j9kg00qf 645 35 and and CC cord-022526-j9kg00qf 645 36 profuse profuse JJ cord-022526-j9kg00qf 645 37 watery watery JJ cord-022526-j9kg00qf 645 38 diarrhea diarrhea NN cord-022526-j9kg00qf 645 39 with with IN cord-022526-j9kg00qf 645 40 resultant resultant JJ cord-022526-j9kg00qf 645 41 endotoxemia endotoxemia NN cord-022526-j9kg00qf 645 42 , , , cord-022526-j9kg00qf 645 43 leukopenia leukopenia NN cord-022526-j9kg00qf 645 44 , , , cord-022526-j9kg00qf 645 45 and and CC cord-022526-j9kg00qf 645 46 hypovolemia hypovolemia NN cord-022526-j9kg00qf 645 47 . . . cord-022526-j9kg00qf 646 1 7 7 CD cord-022526-j9kg00qf 646 2 , , , cord-022526-j9kg00qf 646 3 10 10 CD cord-022526-j9kg00qf 646 4 , , , cord-022526-j9kg00qf 646 5 11 11 CD cord-022526-j9kg00qf 646 6 The the DT cord-022526-j9kg00qf 646 7 condition condition NN cord-022526-j9kg00qf 646 8 can can MD cord-022526-j9kg00qf 646 9 affect affect VB cord-022526-j9kg00qf 646 10 adult adult NN cord-022526-j9kg00qf 646 11 horses horse NNS cord-022526-j9kg00qf 646 12 of of IN cord-022526-j9kg00qf 646 13 all all DT cord-022526-j9kg00qf 646 14 ages age NNS cord-022526-j9kg00qf 646 15 but but CC cord-022526-j9kg00qf 646 16 usually usually RB cord-022526-j9kg00qf 646 17 occurs occur VBZ cord-022526-j9kg00qf 646 18 in in IN cord-022526-j9kg00qf 646 19 horses horse NNS cord-022526-j9kg00qf 646 20 between between IN cord-022526-j9kg00qf 646 21 2 2 CD cord-022526-j9kg00qf 646 22 and and CC cord-022526-j9kg00qf 646 23 10 10 CD cord-022526-j9kg00qf 646 24 years year NNS cord-022526-j9kg00qf 646 25 of of IN cord-022526-j9kg00qf 646 26 age age NN cord-022526-j9kg00qf 646 27 . . . cord-022526-j9kg00qf 647 1 Disease Disease NNP cord-022526-j9kg00qf 647 2 onset onset NN cord-022526-j9kg00qf 647 3 is be VBZ cord-022526-j9kg00qf 647 4 sudden sudden JJ cord-022526-j9kg00qf 647 5 with with IN cord-022526-j9kg00qf 647 6 a a DT cord-022526-j9kg00qf 647 7 rapid rapid JJ cord-022526-j9kg00qf 647 8 progression progression NN cord-022526-j9kg00qf 647 9 and and CC cord-022526-j9kg00qf 647 10 often often RB cord-022526-j9kg00qf 647 11 is be VBZ cord-022526-j9kg00qf 647 12 preceded precede VBN cord-022526-j9kg00qf 647 13 by by IN cord-022526-j9kg00qf 647 14 a a DT cord-022526-j9kg00qf 647 15 stressful stressful JJ cord-022526-j9kg00qf 647 16 event event NN cord-022526-j9kg00qf 647 17 . . . cord-022526-j9kg00qf 648 1 A a DT cord-022526-j9kg00qf 648 2 definitive definitive JJ cord-022526-j9kg00qf 648 3 diagnosis diagnosis NN cord-022526-j9kg00qf 648 4 is be VBZ cord-022526-j9kg00qf 648 5 made make VBN cord-022526-j9kg00qf 648 6 in in IN cord-022526-j9kg00qf 648 7 only only RB cord-022526-j9kg00qf 648 8 about about RB cord-022526-j9kg00qf 648 9 20 20 CD cord-022526-j9kg00qf 648 10 % % NN cord-022526-j9kg00qf 648 11 to to TO cord-022526-j9kg00qf 648 12 30 30 CD cord-022526-j9kg00qf 648 13 % % NN cord-022526-j9kg00qf 648 14 of of IN cord-022526-j9kg00qf 648 15 cases case NNS cord-022526-j9kg00qf 648 16 . . . cord-022526-j9kg00qf 649 1 7 7 CD cord-022526-j9kg00qf 649 2 , , , cord-022526-j9kg00qf 649 3 11 11 CD cord-022526-j9kg00qf 649 4 Most most RBS cord-022526-j9kg00qf 649 5 ante ante NN cord-022526-j9kg00qf 649 6 - - HYPH cord-022526-j9kg00qf 649 7 and and CC cord-022526-j9kg00qf 649 8 postmortem postmortem JJ cord-022526-j9kg00qf 649 9 diagnostic diagnostic JJ cord-022526-j9kg00qf 649 10 tests test NNS cord-022526-j9kg00qf 649 11 remain remain VBP cord-022526-j9kg00qf 649 12 speculative speculative JJ cord-022526-j9kg00qf 649 13 . . . cord-022526-j9kg00qf 650 1 Treatment treatment NN cord-022526-j9kg00qf 650 2 of of IN cord-022526-j9kg00qf 650 3 the the DT cord-022526-j9kg00qf 650 4 condition condition NN cord-022526-j9kg00qf 650 5 in in IN cord-022526-j9kg00qf 650 6 horses horse NNS cord-022526-j9kg00qf 650 7 is be VBZ cord-022526-j9kg00qf 650 8 costly costly JJ cord-022526-j9kg00qf 650 9 because because IN cord-022526-j9kg00qf 650 10 of of IN cord-022526-j9kg00qf 650 11 the the DT cord-022526-j9kg00qf 650 12 massive massive JJ cord-022526-j9kg00qf 650 13 fluid fluid JJ cord-022526-j9kg00qf 650 14 therapy therapy NN cord-022526-j9kg00qf 650 15 required require VBN cord-022526-j9kg00qf 650 16 . . . cord-022526-j9kg00qf 651 1 Currently currently RB cord-022526-j9kg00qf 651 2 , , , cord-022526-j9kg00qf 651 3 no no DT cord-022526-j9kg00qf 651 4 curative curative JJ cord-022526-j9kg00qf 651 5 treatment treatment NN cord-022526-j9kg00qf 651 6 is be VBZ cord-022526-j9kg00qf 651 7 available available JJ cord-022526-j9kg00qf 651 8 for for IN cord-022526-j9kg00qf 651 9 acute acute JJ cord-022526-j9kg00qf 651 10 colitis colitis NN cord-022526-j9kg00qf 651 11 in in IN cord-022526-j9kg00qf 651 12 horses horse NNS cord-022526-j9kg00qf 651 13 , , , cord-022526-j9kg00qf 651 14 human human JJ cord-022526-j9kg00qf 651 15 beings being NNS cord-022526-j9kg00qf 651 16 , , , cord-022526-j9kg00qf 651 17 or or CC cord-022526-j9kg00qf 651 18 other other JJ cord-022526-j9kg00qf 651 19 mammals mammal NNS cord-022526-j9kg00qf 651 20 . . . cord-022526-j9kg00qf 652 1 Treatment treatment NN cord-022526-j9kg00qf 652 2 regimens regimen NNS cord-022526-j9kg00qf 652 3 provide provide VBP cord-022526-j9kg00qf 652 4 rehydration rehydration NN cord-022526-j9kg00qf 652 5 , , , cord-022526-j9kg00qf 652 6 electrolyte electrolyte NN cord-022526-j9kg00qf 652 7 and and CC cord-022526-j9kg00qf 652 8 plasma plasma NN cord-022526-j9kg00qf 652 9 protein protein NN cord-022526-j9kg00qf 652 10 replacement replacement NN cord-022526-j9kg00qf 652 11 , , , cord-022526-j9kg00qf 652 12 mitigation mitigation NN cord-022526-j9kg00qf 652 13 of of IN cord-022526-j9kg00qf 652 14 the the DT cord-022526-j9kg00qf 652 15 effects effect NNS cord-022526-j9kg00qf 652 16 of of IN cord-022526-j9kg00qf 652 17 circulating circulate VBG cord-022526-j9kg00qf 652 18 endotoxin endotoxin NN cord-022526-j9kg00qf 652 19 , , , cord-022526-j9kg00qf 652 20 and and CC cord-022526-j9kg00qf 652 21 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 652 22 therapy therapy NN cord-022526-j9kg00qf 652 23 when when WRB cord-022526-j9kg00qf 652 24 indicated indicate VBN cord-022526-j9kg00qf 652 25 . . . cord-022526-j9kg00qf 653 1 Attempts attempt NNS cord-022526-j9kg00qf 653 2 during during IN cord-022526-j9kg00qf 653 3 the the DT cord-022526-j9kg00qf 653 4 past past JJ cord-022526-j9kg00qf 653 5 40 40 CD cord-022526-j9kg00qf 653 6 years year NNS cord-022526-j9kg00qf 653 7 to to TO cord-022526-j9kg00qf 653 8 develop develop VB cord-022526-j9kg00qf 653 9 appropriate appropriate JJ cord-022526-j9kg00qf 653 10 treatments treatment NNS cord-022526-j9kg00qf 653 11 ( ( -LRB- cord-022526-j9kg00qf 653 12 i.e. i.e. FW cord-022526-j9kg00qf 653 13 , , , cord-022526-j9kg00qf 653 14 vaccines vaccine NNS cord-022526-j9kg00qf 653 15 or or CC cord-022526-j9kg00qf 653 16 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 653 17 agents agent NNS cord-022526-j9kg00qf 653 18 ) ) -RRB- cord-022526-j9kg00qf 653 19 have have VBP cord-022526-j9kg00qf 653 20 been be VBN cord-022526-j9kg00qf 653 21 hampered hamper VBN cord-022526-j9kg00qf 653 22 by by IN cord-022526-j9kg00qf 653 23 the the DT cord-022526-j9kg00qf 653 24 unavailability unavailability NN cord-022526-j9kg00qf 653 25 of of IN cord-022526-j9kg00qf 653 26 acceptable acceptable JJ cord-022526-j9kg00qf 653 27 equine equine JJ cord-022526-j9kg00qf 653 28 models model NNS cord-022526-j9kg00qf 653 29 and and CC cord-022526-j9kg00qf 653 30 have have VBP cord-022526-j9kg00qf 653 31 been be VBN cord-022526-j9kg00qf 653 32 unsuccessful unsuccessful JJ cord-022526-j9kg00qf 653 33 because because IN cord-022526-j9kg00qf 653 34 of of IN cord-022526-j9kg00qf 653 35 the the DT cord-022526-j9kg00qf 653 36 complex complex JJ cord-022526-j9kg00qf 653 37 pathophysiology pathophysiology NN cord-022526-j9kg00qf 653 38 of of IN cord-022526-j9kg00qf 653 39 the the DT cord-022526-j9kg00qf 653 40 intestinal intestinal JJ cord-022526-j9kg00qf 653 41 epithelium epithelium NN cord-022526-j9kg00qf 653 42 . . . cord-022526-j9kg00qf 654 1 Although although IN cord-022526-j9kg00qf 654 2 the the DT cord-022526-j9kg00qf 654 3 mechanisms mechanism NNS cord-022526-j9kg00qf 654 4 responsible responsible JJ cord-022526-j9kg00qf 654 5 for for IN cord-022526-j9kg00qf 654 6 the the DT cord-022526-j9kg00qf 654 7 fluid fluid JJ cord-022526-j9kg00qf 654 8 losses loss NNS cord-022526-j9kg00qf 654 9 are be VBP cord-022526-j9kg00qf 654 10 not not RB cord-022526-j9kg00qf 654 11 known know VBN cord-022526-j9kg00qf 654 12 , , , cord-022526-j9kg00qf 654 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 654 14 cells cell NNS cord-022526-j9kg00qf 654 15 may may MD cord-022526-j9kg00qf 654 16 play play VB cord-022526-j9kg00qf 654 17 an an DT cord-022526-j9kg00qf 654 18 integral integral JJ cord-022526-j9kg00qf 654 19 role role NN cord-022526-j9kg00qf 654 20 because because IN cord-022526-j9kg00qf 654 21 this this DT cord-022526-j9kg00qf 654 22 condition condition NN cord-022526-j9kg00qf 654 23 is be VBZ cord-022526-j9kg00qf 654 24 characterized characterize VBN cord-022526-j9kg00qf 654 25 by by IN cord-022526-j9kg00qf 654 26 large large JJ cord-022526-j9kg00qf 654 27 numbers number NNS cord-022526-j9kg00qf 654 28 of of IN cord-022526-j9kg00qf 654 29 granulocytes granulocyte NNS cord-022526-j9kg00qf 654 30 infiltrating infiltrate VBG cord-022526-j9kg00qf 654 31 the the DT cord-022526-j9kg00qf 654 32 large large JJ cord-022526-j9kg00qf 654 33 intestinal intestinal JJ cord-022526-j9kg00qf 654 34 mucosa mucosa NN cord-022526-j9kg00qf 654 35 . . . cord-022526-j9kg00qf 655 1 [ [ -LRB- cord-022526-j9kg00qf 655 2 12 12 CD cord-022526-j9kg00qf 655 3 ] ] -RRB- cord-022526-j9kg00qf 655 4 [ [ -LRB- cord-022526-j9kg00qf 655 5 13 13 CD cord-022526-j9kg00qf 655 6 ] ] -RRB- cord-022526-j9kg00qf 655 7 [ [ -LRB- cord-022526-j9kg00qf 655 8 14 14 CD cord-022526-j9kg00qf 655 9 ] ] -RRB- cord-022526-j9kg00qf 656 1 [ [ -LRB- cord-022526-j9kg00qf 656 2 15 15 CD cord-022526-j9kg00qf 656 3 ] ] -RRB- cord-022526-j9kg00qf 656 4 [ [ -LRB- cord-022526-j9kg00qf 656 5 16 16 CD cord-022526-j9kg00qf 656 6 ] ] -RRB- cord-022526-j9kg00qf 656 7 Equine equine JJ cord-022526-j9kg00qf 656 8 cecal cecal NN cord-022526-j9kg00qf 656 9 and and CC cord-022526-j9kg00qf 656 10 colonic colonic JJ cord-022526-j9kg00qf 656 11 tissues tissue NNS cord-022526-j9kg00qf 656 12 collected collect VBN cord-022526-j9kg00qf 656 13 during during IN cord-022526-j9kg00qf 656 14 the the DT cord-022526-j9kg00qf 656 15 acute acute JJ cord-022526-j9kg00qf 656 16 stages stage NNS cord-022526-j9kg00qf 656 17 of of IN cord-022526-j9kg00qf 656 18 experimentally experimentally RB cord-022526-j9kg00qf 656 19 induced induce VBN cord-022526-j9kg00qf 656 20 acute acute JJ cord-022526-j9kg00qf 656 21 equine equine JJ cord-022526-j9kg00qf 656 22 colitis colitis NN cord-022526-j9kg00qf 656 23 ( ( -LRB- cord-022526-j9kg00qf 656 24 equine equine JJ cord-022526-j9kg00qf 656 25 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 656 26 colitis colitis NN cord-022526-j9kg00qf 656 27 , , , cord-022526-j9kg00qf 656 28 lincomycin lincomycin NNS cord-022526-j9kg00qf 656 29 with with IN cord-022526-j9kg00qf 656 30 and and CC cord-022526-j9kg00qf 656 31 without without IN cord-022526-j9kg00qf 656 32 Clostridium clostridium NN cord-022526-j9kg00qf 656 33 spp spp NNS cord-022526-j9kg00qf 656 34 . . . cord-022526-j9kg00qf 657 1 inoculation inoculation NN cord-022526-j9kg00qf 657 2 , , , cord-022526-j9kg00qf 657 3 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 657 4 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 657 5 drug drug NN cord-022526-j9kg00qf 657 6 administration administration NNP cord-022526-j9kg00qf 657 7 ) ) -RRB- cord-022526-j9kg00qf 657 8 reveal reveal VB cord-022526-j9kg00qf 657 9 the the DT cord-022526-j9kg00qf 657 10 presence presence NN cord-022526-j9kg00qf 657 11 of of IN cord-022526-j9kg00qf 657 12 numerous numerous JJ cord-022526-j9kg00qf 657 13 neutrophils neutrophil NNS cord-022526-j9kg00qf 657 14 and and CC cord-022526-j9kg00qf 657 15 eosinophils eosinophil NNS cord-022526-j9kg00qf 657 16 in in IN cord-022526-j9kg00qf 657 17 the the DT cord-022526-j9kg00qf 657 18 lamina lamina JJ cord-022526-j9kg00qf 657 19 propria propria NNP cord-022526-j9kg00qf 657 20 and and CC cord-022526-j9kg00qf 657 21 submucosa submucosa NNP cord-022526-j9kg00qf 657 22 . . . cord-022526-j9kg00qf 658 1 12 12 CD cord-022526-j9kg00qf 658 2 , , , cord-022526-j9kg00qf 658 3 15 15 CD cord-022526-j9kg00qf 658 4 , , , cord-022526-j9kg00qf 658 5 17 17 CD cord-022526-j9kg00qf 658 6 , , , cord-022526-j9kg00qf 658 7 18 18 CD cord-022526-j9kg00qf 658 8 Granulocytederived Granulocytederived NNP cord-022526-j9kg00qf 658 9 reactive reactive JJ cord-022526-j9kg00qf 658 10 oxygen oxygen NN cord-022526-j9kg00qf 658 11 intermediates intermediate NNS cord-022526-j9kg00qf 658 12 are be VBP cord-022526-j9kg00qf 658 13 crucial crucial JJ cord-022526-j9kg00qf 658 14 to to IN cord-022526-j9kg00qf 658 15 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 658 16 defenses defense NNS cord-022526-j9kg00qf 658 17 in in IN cord-022526-j9kg00qf 658 18 the the DT cord-022526-j9kg00qf 658 19 gut gut NN cord-022526-j9kg00qf 658 20 and and CC cord-022526-j9kg00qf 658 21 stimulate stimulate VBP cord-022526-j9kg00qf 658 22 chloride chloride NN cord-022526-j9kg00qf 658 23 and and CC cord-022526-j9kg00qf 658 24 water water NN cord-022526-j9kg00qf 658 25 secretion secretion NN cord-022526-j9kg00qf 658 26 by by IN cord-022526-j9kg00qf 658 27 interactions interaction NNS cord-022526-j9kg00qf 658 28 with with IN cord-022526-j9kg00qf 658 29 enterocytes enterocyte NNS cord-022526-j9kg00qf 658 30 . . . cord-022526-j9kg00qf 659 1 19 19 CD cord-022526-j9kg00qf 659 2 , , , cord-022526-j9kg00qf 659 3 20 20 CD cord-022526-j9kg00qf 659 4 Normal normal JJ cord-022526-j9kg00qf 659 5 equine equine JJ cord-022526-j9kg00qf 659 6 intestinal intestinal JJ cord-022526-j9kg00qf 659 7 tissue tissue NN cord-022526-j9kg00qf 659 8 is be VBZ cord-022526-j9kg00qf 659 9 unique unique JJ cord-022526-j9kg00qf 659 10 compared compare VBN cord-022526-j9kg00qf 659 11 with with IN cord-022526-j9kg00qf 659 12 that that DT cord-022526-j9kg00qf 659 13 in in IN cord-022526-j9kg00qf 659 14 most most JJS cord-022526-j9kg00qf 659 15 other other JJ cord-022526-j9kg00qf 659 16 mammalian mammalian JJ cord-022526-j9kg00qf 659 17 species specie NNS cord-022526-j9kg00qf 659 18 for for IN cord-022526-j9kg00qf 659 19 a a DT cord-022526-j9kg00qf 659 20 preponderance preponderance NN cord-022526-j9kg00qf 659 21 of of IN cord-022526-j9kg00qf 659 22 eosinophils eosinophil NNS cord-022526-j9kg00qf 659 23 located locate VBN cord-022526-j9kg00qf 659 24 in in IN cord-022526-j9kg00qf 659 25 the the DT cord-022526-j9kg00qf 659 26 intestinal intestinal JJ cord-022526-j9kg00qf 659 27 mucosa mucosa NN cord-022526-j9kg00qf 659 28 and and CC cord-022526-j9kg00qf 659 29 submucosa submucosa NNP cord-022526-j9kg00qf 659 30 . . . cord-022526-j9kg00qf 660 1 6 6 CD cord-022526-j9kg00qf 660 2 , , , cord-022526-j9kg00qf 660 3 21 21 CD cord-022526-j9kg00qf 660 4 Production production NN cord-022526-j9kg00qf 660 5 of of IN cord-022526-j9kg00qf 660 6 reactive reactive JJ cord-022526-j9kg00qf 660 7 oxygen oxygen NN cord-022526-j9kg00qf 660 8 intermediates intermediate NNS cord-022526-j9kg00qf 660 9 by by IN cord-022526-j9kg00qf 660 10 stimulated stimulate VBN cord-022526-j9kg00qf 660 11 phagocytic phagocytic JJ cord-022526-j9kg00qf 660 12 granulocytes granulocyte NNS cord-022526-j9kg00qf 660 13 following follow VBG cord-022526-j9kg00qf 660 14 mucosal mucosal JJ cord-022526-j9kg00qf 660 15 barrier barrier NN cord-022526-j9kg00qf 660 16 disruption disruption NN cord-022526-j9kg00qf 660 17 may may MD cord-022526-j9kg00qf 660 18 be be VB cord-022526-j9kg00qf 660 19 responsible responsible JJ cord-022526-j9kg00qf 660 20 for for IN cord-022526-j9kg00qf 660 21 the the DT cord-022526-j9kg00qf 660 22 massive massive JJ cord-022526-j9kg00qf 660 23 fluid fluid JJ cord-022526-j9kg00qf 660 24 secretory secretory NN cord-022526-j9kg00qf 660 25 response response NN cord-022526-j9kg00qf 660 26 that that WDT cord-022526-j9kg00qf 660 27 occurs occur VBZ cord-022526-j9kg00qf 660 28 during during IN cord-022526-j9kg00qf 660 29 the the DT cord-022526-j9kg00qf 660 30 early early JJ cord-022526-j9kg00qf 660 31 stages stage NNS cord-022526-j9kg00qf 660 32 of of IN cord-022526-j9kg00qf 660 33 acute acute JJ cord-022526-j9kg00qf 660 34 equine equine JJ cord-022526-j9kg00qf 660 35 colitis colitis NN cord-022526-j9kg00qf 660 36 . . . cord-022526-j9kg00qf 661 1 Colitis colitis NN cord-022526-j9kg00qf 661 2 refers refer VBZ cord-022526-j9kg00qf 661 3 to to IN cord-022526-j9kg00qf 661 4 inflammation inflammation NN cord-022526-j9kg00qf 661 5 and and CC cord-022526-j9kg00qf 661 6 mucosal mucosal JJ cord-022526-j9kg00qf 661 7 injury injury NN cord-022526-j9kg00qf 661 8 of of IN cord-022526-j9kg00qf 661 9 the the DT cord-022526-j9kg00qf 661 10 colon colon NN cord-022526-j9kg00qf 661 11 and and CC cord-022526-j9kg00qf 661 12 cecum cecum NN cord-022526-j9kg00qf 661 13 ( ( -LRB- cord-022526-j9kg00qf 661 14 typhlocolitis typhlocolitis NNP cord-022526-j9kg00qf 661 15 ) ) -RRB- cord-022526-j9kg00qf 661 16 that that WDT cord-022526-j9kg00qf 661 17 may may MD cord-022526-j9kg00qf 661 18 occur occur VB cord-022526-j9kg00qf 661 19 in in IN cord-022526-j9kg00qf 661 20 response response NN cord-022526-j9kg00qf 661 21 to to IN cord-022526-j9kg00qf 661 22 a a DT cord-022526-j9kg00qf 661 23 number number NN cord-022526-j9kg00qf 661 24 of of IN cord-022526-j9kg00qf 661 25 causes cause NNS cord-022526-j9kg00qf 661 26 . . . cord-022526-j9kg00qf 662 1 22 22 CD cord-022526-j9kg00qf 662 2 , , , cord-022526-j9kg00qf 662 3 23 23 CD cord-022526-j9kg00qf 663 1 The the DT cord-022526-j9kg00qf 663 2 cause cause NN cord-022526-j9kg00qf 663 3 of of IN cord-022526-j9kg00qf 663 4 the the DT cord-022526-j9kg00qf 663 5 colonic colonic JJ cord-022526-j9kg00qf 663 6 injury injury NN cord-022526-j9kg00qf 663 7 may may MD cord-022526-j9kg00qf 663 8 be be VB cord-022526-j9kg00qf 663 9 well well RB cord-022526-j9kg00qf 663 10 - - HYPH cord-022526-j9kg00qf 663 11 defined define VBN cord-022526-j9kg00qf 663 12 such such JJ cord-022526-j9kg00qf 663 13 as as IN cord-022526-j9kg00qf 663 14 in in IN cord-022526-j9kg00qf 663 15 naturally naturally RB cord-022526-j9kg00qf 663 16 occurring occur VBG cord-022526-j9kg00qf 663 17 infectious infectious JJ cord-022526-j9kg00qf 663 18 or or CC cord-022526-j9kg00qf 663 19 experimentally experimentally RB cord-022526-j9kg00qf 663 20 induced induce VBN cord-022526-j9kg00qf 663 21 colitis colitis NN cord-022526-j9kg00qf 663 22 . . . cord-022526-j9kg00qf 664 1 However however RB cord-022526-j9kg00qf 664 2 , , , cord-022526-j9kg00qf 664 3 many many JJ cord-022526-j9kg00qf 664 4 cases case NNS cord-022526-j9kg00qf 664 5 of of IN cord-022526-j9kg00qf 664 6 human human JJ cord-022526-j9kg00qf 664 7 and and CC cord-022526-j9kg00qf 664 8 animal animal NN cord-022526-j9kg00qf 664 9 diarrhea diarrhea NN cord-022526-j9kg00qf 664 10 have have VBP cord-022526-j9kg00qf 664 11 a a DT cord-022526-j9kg00qf 664 12 speculative speculative JJ cord-022526-j9kg00qf 664 13 or or CC cord-022526-j9kg00qf 664 14 unknown unknown JJ cord-022526-j9kg00qf 664 15 diagnosis diagnosis NN cord-022526-j9kg00qf 664 16 or or CC cord-022526-j9kg00qf 664 17 no no DT cord-022526-j9kg00qf 664 18 diagnosis diagnosis NN cord-022526-j9kg00qf 664 19 . . . cord-022526-j9kg00qf 665 1 11 11 CD cord-022526-j9kg00qf 665 2 , , , cord-022526-j9kg00qf 665 3 24 24 CD cord-022526-j9kg00qf 666 1 , , , cord-022526-j9kg00qf 666 2 25 25 CD cord-022526-j9kg00qf 666 3 Irrespective Irrespective NNP cord-022526-j9kg00qf 666 4 of of IN cord-022526-j9kg00qf 666 5 the the DT cord-022526-j9kg00qf 666 6 underlying underlie VBG cord-022526-j9kg00qf 666 7 or or CC cord-022526-j9kg00qf 666 8 initiating initiate VBG cord-022526-j9kg00qf 666 9 cause cause NN cord-022526-j9kg00qf 666 10 of of IN cord-022526-j9kg00qf 666 11 colonic colonic JJ cord-022526-j9kg00qf 666 12 injury injury NN cord-022526-j9kg00qf 666 13 , , , cord-022526-j9kg00qf 666 14 the the DT cord-022526-j9kg00qf 666 15 colon colon NN cord-022526-j9kg00qf 666 16 apparently apparently RB cord-022526-j9kg00qf 666 17 has have VBZ cord-022526-j9kg00qf 666 18 a a DT cord-022526-j9kg00qf 666 19 limited limited JJ cord-022526-j9kg00qf 666 20 repertoire repertoire NN cord-022526-j9kg00qf 666 21 of of IN cord-022526-j9kg00qf 666 22 responses response NNS cord-022526-j9kg00qf 666 23 to to TO cord-022526-j9kg00qf 666 24 damage damage VB cord-022526-j9kg00qf 666 25 because because IN cord-022526-j9kg00qf 666 26 most most JJS cord-022526-j9kg00qf 666 27 forms form NNS cord-022526-j9kg00qf 666 28 of of IN cord-022526-j9kg00qf 666 29 colitis colitis NN cord-022526-j9kg00qf 666 30 demonstrate demonstrate VBP cord-022526-j9kg00qf 666 31 similarities similarity NNS cord-022526-j9kg00qf 666 32 in in IN cord-022526-j9kg00qf 666 33 histopathologic histopathologic JJ cord-022526-j9kg00qf 666 34 appearance appearance NN cord-022526-j9kg00qf 666 35 and and CC cord-022526-j9kg00qf 666 36 clinical clinical JJ cord-022526-j9kg00qf 666 37 presentation presentation NN cord-022526-j9kg00qf 666 38 . . . cord-022526-j9kg00qf 667 1 Various various JJ cord-022526-j9kg00qf 667 2 degrees degree NNS cord-022526-j9kg00qf 667 3 of of IN cord-022526-j9kg00qf 667 4 mucosal mucosal JJ cord-022526-j9kg00qf 667 5 erosion erosion NN cord-022526-j9kg00qf 667 6 and and CC cord-022526-j9kg00qf 667 7 ulceration ulceration NN cord-022526-j9kg00qf 667 8 , , , cord-022526-j9kg00qf 667 9 submucosal submucosal NN cord-022526-j9kg00qf 667 10 / / SYM cord-022526-j9kg00qf 667 11 mucosal mucosal JJ cord-022526-j9kg00qf 667 12 edema edema NN cord-022526-j9kg00qf 667 13 , , , cord-022526-j9kg00qf 667 14 goblet goblet NN cord-022526-j9kg00qf 667 15 cell cell NN cord-022526-j9kg00qf 667 16 depletion depletion NN cord-022526-j9kg00qf 667 17 , , , cord-022526-j9kg00qf 667 18 and and CC cord-022526-j9kg00qf 667 19 presence presence NN cord-022526-j9kg00qf 667 20 of of IN cord-022526-j9kg00qf 667 21 an an DT cord-022526-j9kg00qf 667 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 667 23 cellular cellular JJ cord-022526-j9kg00qf 667 24 infiltrate infiltrate NN cord-022526-j9kg00qf 667 25 within within IN cord-022526-j9kg00qf 667 26 the the DT cord-022526-j9kg00qf 667 27 mucosa mucosa JJ cord-022526-j9kg00qf 667 28 and and CC cord-022526-j9kg00qf 667 29 submucosa submucosa NNP cord-022526-j9kg00qf 667 30 are be VBP cord-022526-j9kg00qf 667 31 common common JJ cord-022526-j9kg00qf 667 32 to to IN cord-022526-j9kg00qf 667 33 many many JJ cord-022526-j9kg00qf 667 34 types type NNS cord-022526-j9kg00qf 667 35 of of IN cord-022526-j9kg00qf 667 36 human human JJ cord-022526-j9kg00qf 667 37 and and CC cord-022526-j9kg00qf 667 38 animal animal NN cord-022526-j9kg00qf 667 39 colitis colitis NN cord-022526-j9kg00qf 667 40 . . . cord-022526-j9kg00qf 668 1 21 21 CD cord-022526-j9kg00qf 668 2 , , , cord-022526-j9kg00qf 668 3 [ [ -LRB- cord-022526-j9kg00qf 668 4 23 23 CD cord-022526-j9kg00qf 668 5 ] ] -RRB- cord-022526-j9kg00qf 668 6 [ [ -LRB- cord-022526-j9kg00qf 668 7 24 24 CD cord-022526-j9kg00qf 668 8 ] ] -RRB- cord-022526-j9kg00qf 668 9 [ [ -LRB- cord-022526-j9kg00qf 668 10 25 25 CD cord-022526-j9kg00qf 668 11 ] ] -RRB- cord-022526-j9kg00qf 669 1 Characteristic characteristic JJ cord-022526-j9kg00qf 669 2 clinical clinical JJ cord-022526-j9kg00qf 669 3 manifestations manifestation NNS cord-022526-j9kg00qf 669 4 include include VBP cord-022526-j9kg00qf 669 5 intraluminal intraluminal JJ cord-022526-j9kg00qf 669 6 fluid fluid JJ cord-022526-j9kg00qf 669 7 sequestration sequestration NN cord-022526-j9kg00qf 669 8 , , , cord-022526-j9kg00qf 669 9 abdominal abdominal JJ cord-022526-j9kg00qf 669 10 discomfort discomfort NN cord-022526-j9kg00qf 669 11 , , , cord-022526-j9kg00qf 669 12 hypovolemia hypovolemia NN cord-022526-j9kg00qf 669 13 , , , cord-022526-j9kg00qf 669 14 and and CC cord-022526-j9kg00qf 669 15 most most RBS cord-022526-j9kg00qf 669 16 often often RB cord-022526-j9kg00qf 669 17 profuse profuse JJ cord-022526-j9kg00qf 669 18 , , , cord-022526-j9kg00qf 669 19 watery watery JJ cord-022526-j9kg00qf 669 20 diarrhea diarrhea NN cord-022526-j9kg00qf 669 21 . . . cord-022526-j9kg00qf 670 1 Large large JJ cord-022526-j9kg00qf 670 2 bowel bowel NN cord-022526-j9kg00qf 670 3 diarrhea diarrhea NN cord-022526-j9kg00qf 670 4 results result NNS cord-022526-j9kg00qf 670 5 from from IN cord-022526-j9kg00qf 670 6 abnormal abnormal JJ cord-022526-j9kg00qf 670 7 fluid fluid NN cord-022526-j9kg00qf 670 8 and and CC cord-022526-j9kg00qf 670 9 ion ion NN cord-022526-j9kg00qf 670 10 transport transport NN cord-022526-j9kg00qf 670 11 by by IN cord-022526-j9kg00qf 670 12 cecal cecal JJ cord-022526-j9kg00qf 670 13 and and CC cord-022526-j9kg00qf 670 14 colonic colonic JJ cord-022526-j9kg00qf 670 15 mucosa mucosa NN cord-022526-j9kg00qf 670 16 . . . cord-022526-j9kg00qf 671 1 Loss loss NN cord-022526-j9kg00qf 671 2 of of IN cord-022526-j9kg00qf 671 3 fluid fluid NN cord-022526-j9kg00qf 671 4 by by IN cord-022526-j9kg00qf 671 5 the the DT cord-022526-j9kg00qf 671 6 large large JJ cord-022526-j9kg00qf 671 7 intestine intestine NN cord-022526-j9kg00qf 671 8 can can MD cord-022526-j9kg00qf 671 9 result result VB cord-022526-j9kg00qf 671 10 from from IN cord-022526-j9kg00qf 671 11 malabsorptive malabsorptive NNP cord-022526-j9kg00qf 671 12 or or CC cord-022526-j9kg00qf 671 13 hypersecretory hypersecretory NNP cord-022526-j9kg00qf 671 14 processes process NNS cord-022526-j9kg00qf 671 15 and and CC cord-022526-j9kg00qf 671 16 is be VBZ cord-022526-j9kg00qf 671 17 often often RB cord-022526-j9kg00qf 671 18 a a DT cord-022526-j9kg00qf 671 19 combination combination NN cord-022526-j9kg00qf 671 20 of of IN cord-022526-j9kg00qf 671 21 the the DT cord-022526-j9kg00qf 671 22 two two CD cord-022526-j9kg00qf 671 23 . . . cord-022526-j9kg00qf 672 1 26 26 CD cord-022526-j9kg00qf 672 2 Colonic colonic JJ cord-022526-j9kg00qf 672 3 secretory secretory JJ cord-022526-j9kg00qf 672 4 processes process NNS cord-022526-j9kg00qf 672 5 are be VBP cord-022526-j9kg00qf 672 6 a a DT cord-022526-j9kg00qf 672 7 function function NN cord-022526-j9kg00qf 672 8 of of IN cord-022526-j9kg00qf 672 9 the the DT cord-022526-j9kg00qf 672 10 crypt crypt JJ cord-022526-j9kg00qf 672 11 epithelium epithelium NN cord-022526-j9kg00qf 672 12 , , , cord-022526-j9kg00qf 672 13 whereas whereas IN cord-022526-j9kg00qf 672 14 absorptive absorptive JJ cord-022526-j9kg00qf 672 15 processes process NNS cord-022526-j9kg00qf 672 16 are be VBP cord-022526-j9kg00qf 672 17 limited limit VBN cord-022526-j9kg00qf 672 18 to to TO cord-022526-j9kg00qf 672 19 surface surface VB cord-022526-j9kg00qf 672 20 epithelial epithelial JJ cord-022526-j9kg00qf 672 21 cells cell NNS cord-022526-j9kg00qf 672 22 . . . cord-022526-j9kg00qf 673 1 27 27 CD cord-022526-j9kg00qf 674 1 Under under IN cord-022526-j9kg00qf 674 2 normal normal JJ cord-022526-j9kg00qf 674 3 baseline baseline JJ cord-022526-j9kg00qf 674 4 conditions condition NNS cord-022526-j9kg00qf 674 5 , , , cord-022526-j9kg00qf 674 6 an an DT cord-022526-j9kg00qf 674 7 underlying underlie VBG cord-022526-j9kg00qf 674 8 secretion secretion NN cord-022526-j9kg00qf 674 9 by by IN cord-022526-j9kg00qf 674 10 crypt crypt JJ cord-022526-j9kg00qf 674 11 epithelium epithelium NN cord-022526-j9kg00qf 674 12 is be VBZ cord-022526-j9kg00qf 674 13 masked mask VBN cord-022526-j9kg00qf 674 14 by by IN cord-022526-j9kg00qf 674 15 a a DT cord-022526-j9kg00qf 674 16 greater great JJR cord-022526-j9kg00qf 674 17 rate rate NN cord-022526-j9kg00qf 674 18 of of IN cord-022526-j9kg00qf 674 19 surface surface NN cord-022526-j9kg00qf 674 20 epithelial epithelial JJ cord-022526-j9kg00qf 674 21 cell cell NN cord-022526-j9kg00qf 674 22 absorption absorption NN cord-022526-j9kg00qf 674 23 . . . cord-022526-j9kg00qf 675 1 Abnormal abnormal JJ cord-022526-j9kg00qf 675 2 forces force NNS cord-022526-j9kg00qf 675 3 influencing influence VBG cord-022526-j9kg00qf 675 4 the the DT cord-022526-j9kg00qf 675 5 rates rate NNS cord-022526-j9kg00qf 675 6 of of IN cord-022526-j9kg00qf 675 7 secretion secretion NN cord-022526-j9kg00qf 675 8 and and CC cord-022526-j9kg00qf 675 9 absorption absorption NN cord-022526-j9kg00qf 675 10 can can MD cord-022526-j9kg00qf 675 11 result result VB cord-022526-j9kg00qf 675 12 in in IN cord-022526-j9kg00qf 675 13 massive massive JJ cord-022526-j9kg00qf 675 14 , , , cord-022526-j9kg00qf 675 15 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 675 16 secretion secretion NN cord-022526-j9kg00qf 675 17 and and CC cord-022526-j9kg00qf 675 18 malabsorption malabsorption NN cord-022526-j9kg00qf 675 19 by by IN cord-022526-j9kg00qf 675 20 large large JJ cord-022526-j9kg00qf 675 21 intestinal intestinal JJ cord-022526-j9kg00qf 675 22 mucosal mucosal JJ cord-022526-j9kg00qf 675 23 epithelial epithelial JJ cord-022526-j9kg00qf 675 24 cells cell NNS cord-022526-j9kg00qf 675 25 , , , cord-022526-j9kg00qf 675 26 leading lead VBG cord-022526-j9kg00qf 675 27 to to IN cord-022526-j9kg00qf 675 28 rapid rapid JJ cord-022526-j9kg00qf 675 29 dehydration dehydration NN cord-022526-j9kg00qf 675 30 and and CC cord-022526-j9kg00qf 675 31 death death NN cord-022526-j9kg00qf 675 32 . . . cord-022526-j9kg00qf 676 1 26 26 CD cord-022526-j9kg00qf 676 2 , , , cord-022526-j9kg00qf 676 3 27 27 CD cord-022526-j9kg00qf 676 4 Two two CD cord-022526-j9kg00qf 676 5 intracellular intracellular JJ cord-022526-j9kg00qf 676 6 processes process NNS cord-022526-j9kg00qf 676 7 control control VBP cord-022526-j9kg00qf 676 8 colonic colonic JJ cord-022526-j9kg00qf 676 9 secretion secretion NN cord-022526-j9kg00qf 676 10 : : : cord-022526-j9kg00qf 676 11 the the DT cord-022526-j9kg00qf 676 12 cyclic cyclic JJ cord-022526-j9kg00qf 676 13 nucleotide nucleotide NN cord-022526-j9kg00qf 676 14 ( ( -LRB- cord-022526-j9kg00qf 676 15 cyclic cyclic JJ cord-022526-j9kg00qf 676 16 adenosine adenosine NN cord-022526-j9kg00qf 676 17 monophosphate monophosphate NN cord-022526-j9kg00qf 676 18 [ [ -LRB- cord-022526-j9kg00qf 676 19 cAMP camp NN cord-022526-j9kg00qf 676 20 ] ] -RRB- cord-022526-j9kg00qf 676 21 and and CC cord-022526-j9kg00qf 676 22 cyclic cyclic JJ cord-022526-j9kg00qf 676 23 guanosine guanosine NN cord-022526-j9kg00qf 676 24 monophosphate monophosphate NN cord-022526-j9kg00qf 676 25 [ [ -LRB- cord-022526-j9kg00qf 676 26 cGMP cGMP NNP cord-022526-j9kg00qf 676 27 ] ] -RRB- cord-022526-j9kg00qf 676 28 ) ) -RRB- cord-022526-j9kg00qf 676 29 and and CC cord-022526-j9kg00qf 676 30 the the DT cord-022526-j9kg00qf 676 31 calcium calcium NN cord-022526-j9kg00qf 676 32 system system NN cord-022526-j9kg00qf 676 33 . . . cord-022526-j9kg00qf 677 1 28 28 CD cord-022526-j9kg00qf 677 2 , , , cord-022526-j9kg00qf 677 3 29 29 CD cord-022526-j9kg00qf 677 4 Agents agent NNS cord-022526-j9kg00qf 677 5 may may MD cord-022526-j9kg00qf 677 6 activate activate VB cord-022526-j9kg00qf 677 7 adenyl adenyl NNP cord-022526-j9kg00qf 677 8 cyclase cyclase NN cord-022526-j9kg00qf 677 9 ( ( -LRB- cord-022526-j9kg00qf 677 10 vasoactive vasoactive JJ cord-022526-j9kg00qf 677 11 intestinal intestinal JJ cord-022526-j9kg00qf 677 12 peptide peptide NN cord-022526-j9kg00qf 677 13 , , , cord-022526-j9kg00qf 677 14 prostaglandin prostaglandin NN cord-022526-j9kg00qf 677 15 E e NN cord-022526-j9kg00qf 677 16 2 2 CD cord-022526-j9kg00qf 678 1 [ [ -LRB- cord-022526-j9kg00qf 678 2 PGE PGE NNP cord-022526-j9kg00qf 678 3 2 2 CD cord-022526-j9kg00qf 678 4 ] ] -RRB- cord-022526-j9kg00qf 678 5 ) ) -RRB- cord-022526-j9kg00qf 678 6 or or CC cord-022526-j9kg00qf 678 7 guanyl guanyl NNP cord-022526-j9kg00qf 678 8 cyclase cyclase NN cord-022526-j9kg00qf 678 9 ( ( -LRB- cord-022526-j9kg00qf 678 10 bacterial bacterial JJ cord-022526-j9kg00qf 678 11 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 678 12 ) ) -RRB- cord-022526-j9kg00qf 678 13 and and CC cord-022526-j9kg00qf 678 14 induce induce VB cord-022526-j9kg00qf 678 15 increases increase NNS cord-022526-j9kg00qf 678 16 in in IN cord-022526-j9kg00qf 678 17 cAMP camp NN cord-022526-j9kg00qf 678 18 or or CC cord-022526-j9kg00qf 678 19 cGMP cGMP NNP cord-022526-j9kg00qf 678 20 , , , cord-022526-j9kg00qf 678 21 respectively respectively RB cord-022526-j9kg00qf 678 22 . . . cord-022526-j9kg00qf 679 1 This this DT cord-022526-j9kg00qf 679 2 reaction reaction NN cord-022526-j9kg00qf 679 3 causes cause VBZ cord-022526-j9kg00qf 679 4 phosphorylation phosphorylation NN cord-022526-j9kg00qf 679 5 of of IN cord-022526-j9kg00qf 679 6 specific specific JJ cord-022526-j9kg00qf 679 7 protein protein NN cord-022526-j9kg00qf 679 8 kinases kinase NNS cord-022526-j9kg00qf 679 9 that that WDT cord-022526-j9kg00qf 679 10 induce induce VBP cord-022526-j9kg00qf 679 11 the the DT cord-022526-j9kg00qf 679 12 actual actual JJ cord-022526-j9kg00qf 679 13 apical apical JJ cord-022526-j9kg00qf 679 14 and and CC cord-022526-j9kg00qf 679 15 basolateral basolateral JJ cord-022526-j9kg00qf 679 16 membrane membrane NN cord-022526-j9kg00qf 679 17 transport transport NN cord-022526-j9kg00qf 679 18 events event NNS cord-022526-j9kg00qf 679 19 . . . cord-022526-j9kg00qf 680 1 Increases increase NNS cord-022526-j9kg00qf 680 2 in in IN cord-022526-j9kg00qf 680 3 intracellular intracellular JJ cord-022526-j9kg00qf 680 4 free free JJ cord-022526-j9kg00qf 680 5 calcium calcium NN cord-022526-j9kg00qf 680 6 may may MD cord-022526-j9kg00qf 680 7 arise arise VB cord-022526-j9kg00qf 680 8 from from IN cord-022526-j9kg00qf 680 9 cyclic cyclic JJ cord-022526-j9kg00qf 680 10 nucleotide nucleotide JJ cord-022526-j9kg00qf 680 11 - - HYPH cord-022526-j9kg00qf 680 12 dependent dependent JJ cord-022526-j9kg00qf 680 13 release release NN cord-022526-j9kg00qf 680 14 of of IN cord-022526-j9kg00qf 680 15 stored store VBN cord-022526-j9kg00qf 680 16 calcium calcium NN cord-022526-j9kg00qf 680 17 within within IN cord-022526-j9kg00qf 680 18 the the DT cord-022526-j9kg00qf 680 19 cell cell NN cord-022526-j9kg00qf 680 20 or or CC cord-022526-j9kg00qf 680 21 from from IN cord-022526-j9kg00qf 680 22 increased increase VBN cord-022526-j9kg00qf 680 23 calcium calcium NN cord-022526-j9kg00qf 680 24 entry entry NN cord-022526-j9kg00qf 680 25 across across IN cord-022526-j9kg00qf 680 26 the the DT cord-022526-j9kg00qf 680 27 cell cell NN cord-022526-j9kg00qf 680 28 membrane membrane NN cord-022526-j9kg00qf 680 29 . . . cord-022526-j9kg00qf 681 1 26 26 CD cord-022526-j9kg00qf 681 2 , , , cord-022526-j9kg00qf 681 3 27 27 CD cord-022526-j9kg00qf 681 4 Calcium Calcium NNP cord-022526-j9kg00qf 681 5 may may MD cord-022526-j9kg00qf 681 6 act act VB cord-022526-j9kg00qf 681 7 through through IN cord-022526-j9kg00qf 681 8 calmodulin calmodulin NNP cord-022526-j9kg00qf 681 9 , , , cord-022526-j9kg00qf 681 10 which which WDT cord-022526-j9kg00qf 681 11 then then RB cord-022526-j9kg00qf 681 12 can can MD cord-022526-j9kg00qf 681 13 activate activate VB cord-022526-j9kg00qf 681 14 membranephosphorylating membranephosphorylate VBG cord-022526-j9kg00qf 681 15 protein protein NN cord-022526-j9kg00qf 681 16 kinases kinase NNS cord-022526-j9kg00qf 681 17 . . . cord-022526-j9kg00qf 682 1 At at RB cord-022526-j9kg00qf 682 2 least least JJS cord-022526-j9kg00qf 682 3 four four CD cord-022526-j9kg00qf 682 4 central central JJ cord-022526-j9kg00qf 682 5 systems system NNS cord-022526-j9kg00qf 682 6 control control VBP cord-022526-j9kg00qf 682 7 intestinal intestinal JJ cord-022526-j9kg00qf 682 8 secretion secretion NN cord-022526-j9kg00qf 682 9 : : : cord-022526-j9kg00qf 682 10 ( ( -LRB- cord-022526-j9kg00qf 682 11 1 1 LS cord-022526-j9kg00qf 682 12 ) ) -RRB- cord-022526-j9kg00qf 682 13 the the DT cord-022526-j9kg00qf 682 14 hormonal hormonal JJ cord-022526-j9kg00qf 682 15 system system NN cord-022526-j9kg00qf 682 16 , , , cord-022526-j9kg00qf 682 17 ( ( -LRB- cord-022526-j9kg00qf 682 18 2 2 LS cord-022526-j9kg00qf 682 19 ) ) -RRB- cord-022526-j9kg00qf 682 20 the the DT cord-022526-j9kg00qf 682 21 enteric enteric JJ cord-022526-j9kg00qf 682 22 nervous nervous JJ cord-022526-j9kg00qf 682 23 system system NN cord-022526-j9kg00qf 682 24 , , , cord-022526-j9kg00qf 682 25 ( ( -LRB- cord-022526-j9kg00qf 682 26 3 3 LS cord-022526-j9kg00qf 682 27 ) ) -RRB- cord-022526-j9kg00qf 682 28 bacterial bacterial JJ cord-022526-j9kg00qf 682 29 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 682 30 , , , cord-022526-j9kg00qf 682 31 and and CC cord-022526-j9kg00qf 682 32 ( ( -LRB- cord-022526-j9kg00qf 682 33 4 4 LS cord-022526-j9kg00qf 682 34 ) ) -RRB- cord-022526-j9kg00qf 682 35 the the DT cord-022526-j9kg00qf 682 36 immune immune JJ cord-022526-j9kg00qf 682 37 system system NN cord-022526-j9kg00qf 682 38 . . . cord-022526-j9kg00qf 683 1 29 29 CD cord-022526-j9kg00qf 683 2 , , , cord-022526-j9kg00qf 683 3 30 30 CD cord-022526-j9kg00qf 683 4 Hormonal hormonal JJ cord-022526-j9kg00qf 683 5 control control NN cord-022526-j9kg00qf 683 6 of of IN cord-022526-j9kg00qf 683 7 colonic colonic JJ cord-022526-j9kg00qf 683 8 electrolyte electrolyte JJ cord-022526-j9kg00qf 683 9 transport transport NN cord-022526-j9kg00qf 683 10 is be VBZ cord-022526-j9kg00qf 683 11 exerted exert VBN cord-022526-j9kg00qf 683 12 primarily primarily RB cord-022526-j9kg00qf 683 13 through through IN cord-022526-j9kg00qf 683 14 the the DT cord-022526-j9kg00qf 683 15 renin renin NN cord-022526-j9kg00qf 683 16 - - HYPH cord-022526-j9kg00qf 683 17 angiotensinaldosterone angiotensinaldosterone NN cord-022526-j9kg00qf 683 18 axis axis NN cord-022526-j9kg00qf 683 19 . . . cord-022526-j9kg00qf 684 1 31 31 CD cord-022526-j9kg00qf 684 2 , , , cord-022526-j9kg00qf 684 3 32 32 CD cord-022526-j9kg00qf 684 4 The the DT cord-022526-j9kg00qf 684 5 enteric enteric JJ cord-022526-j9kg00qf 684 6 nervous nervous JJ cord-022526-j9kg00qf 684 7 system system NN cord-022526-j9kg00qf 684 8 controls control VBZ cord-022526-j9kg00qf 684 9 transport transport NN cord-022526-j9kg00qf 684 10 through through IN cord-022526-j9kg00qf 684 11 three three CD cord-022526-j9kg00qf 684 12 separate separate JJ cord-022526-j9kg00qf 684 13 components component NNS cord-022526-j9kg00qf 684 14 : : : cord-022526-j9kg00qf 684 15 ( ( -LRB- cord-022526-j9kg00qf 684 16 1 1 LS cord-022526-j9kg00qf 684 17 ) ) -RRB- cord-022526-j9kg00qf 684 18 extrinsic extrinsic JJ cord-022526-j9kg00qf 684 19 nerves nerve NNS cord-022526-j9kg00qf 684 20 of of IN cord-022526-j9kg00qf 684 21 the the DT cord-022526-j9kg00qf 684 22 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 684 23 and and CC cord-022526-j9kg00qf 684 24 sympathetic sympathetic JJ cord-022526-j9kg00qf 684 25 pathways pathway NNS cord-022526-j9kg00qf 684 26 ; ; , cord-022526-j9kg00qf 684 27 ( ( -LRB- cord-022526-j9kg00qf 684 28 2 2 LS cord-022526-j9kg00qf 684 29 ) ) -RRB- cord-022526-j9kg00qf 684 30 intrinsic intrinsic JJ cord-022526-j9kg00qf 684 31 ganglia ganglion NNS cord-022526-j9kg00qf 684 32 and and CC cord-022526-j9kg00qf 684 33 nerves nerve NNS cord-022526-j9kg00qf 684 34 , , , cord-022526-j9kg00qf 684 35 secreting secrete VBG cord-022526-j9kg00qf 684 36 a a DT cord-022526-j9kg00qf 684 37 variety variety NN cord-022526-j9kg00qf 684 38 of of IN cord-022526-j9kg00qf 684 39 neurotransmitters neurotransmitter NNS cord-022526-j9kg00qf 684 40 including include VBG cord-022526-j9kg00qf 684 41 peptides peptide NNS cord-022526-j9kg00qf 684 42 ; ; : cord-022526-j9kg00qf 684 43 and and CC cord-022526-j9kg00qf 684 44 ( ( -LRB- cord-022526-j9kg00qf 684 45 3 3 LS cord-022526-j9kg00qf 684 46 ) ) -RRB- cord-022526-j9kg00qf 684 47 neuroendocrine neuroendocrine JJ cord-022526-j9kg00qf 684 48 cells cell NNS cord-022526-j9kg00qf 684 49 ( ( -LRB- cord-022526-j9kg00qf 684 50 intraepithelial intraepithelial JJ cord-022526-j9kg00qf 684 51 lymphocytes lymphocyte NNS cord-022526-j9kg00qf 684 52 ) ) -RRB- cord-022526-j9kg00qf 684 53 that that WDT cord-022526-j9kg00qf 684 54 reside reside VBP cord-022526-j9kg00qf 684 55 in in IN cord-022526-j9kg00qf 684 56 the the DT cord-022526-j9kg00qf 684 57 epithelium epithelium NN cord-022526-j9kg00qf 684 58 and and CC cord-022526-j9kg00qf 684 59 release release NN cord-022526-j9kg00qf 684 60 messengers messenger NNS cord-022526-j9kg00qf 684 61 onto onto IN cord-022526-j9kg00qf 684 62 the the DT cord-022526-j9kg00qf 684 63 epithelial epithelial JJ cord-022526-j9kg00qf 684 64 cells cell NNS cord-022526-j9kg00qf 684 65 in in IN cord-022526-j9kg00qf 684 66 a a DT cord-022526-j9kg00qf 684 67 paracrine paracrine JJ cord-022526-j9kg00qf 684 68 manner manner NN cord-022526-j9kg00qf 684 69 . . . cord-022526-j9kg00qf 685 1 26 26 CD cord-022526-j9kg00qf 685 2 , , , cord-022526-j9kg00qf 685 3 [ [ -LRB- cord-022526-j9kg00qf 685 4 29 29 CD cord-022526-j9kg00qf 685 5 ] ] -RRB- cord-022526-j9kg00qf 685 6 [ [ -LRB- cord-022526-j9kg00qf 685 7 30 30 CD cord-022526-j9kg00qf 685 8 ] ] -RRB- cord-022526-j9kg00qf 685 9 [ [ -LRB- cord-022526-j9kg00qf 685 10 31 31 CD cord-022526-j9kg00qf 685 11 ] ] -RRB- cord-022526-j9kg00qf 685 12 [ [ -LRB- cord-022526-j9kg00qf 685 13 32 32 CD cord-022526-j9kg00qf 685 14 ] ] -RRB- cord-022526-j9kg00qf 686 1 Many many JJ cord-022526-j9kg00qf 686 2 bacterial bacterial JJ cord-022526-j9kg00qf 686 3 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 686 4 can can MD cord-022526-j9kg00qf 686 5 induce induce VB cord-022526-j9kg00qf 686 6 intestinal intestinal JJ cord-022526-j9kg00qf 686 7 secretion secretion NN cord-022526-j9kg00qf 686 8 by by IN cord-022526-j9kg00qf 686 9 cAMP camp NN cord-022526-j9kg00qf 686 10 or or CC cord-022526-j9kg00qf 686 11 cGMP cGMP NNP cord-022526-j9kg00qf 686 12 signal signal NN cord-022526-j9kg00qf 686 13 transduction transduction NN cord-022526-j9kg00qf 686 14 . . . cord-022526-j9kg00qf 687 1 33 33 CD cord-022526-j9kg00qf 687 2 Bacterial bacterial JJ cord-022526-j9kg00qf 687 3 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 687 4 can can MD cord-022526-j9kg00qf 687 5 stimulate stimulate VB cord-022526-j9kg00qf 687 6 enteric enteric JJ cord-022526-j9kg00qf 687 7 neurons neuron NNS cord-022526-j9kg00qf 687 8 , , , cord-022526-j9kg00qf 687 9 providing provide VBG cord-022526-j9kg00qf 687 10 evidence evidence NN cord-022526-j9kg00qf 687 11 for for IN cord-022526-j9kg00qf 687 12 interaction interaction NN cord-022526-j9kg00qf 687 13 between between IN cord-022526-j9kg00qf 687 14 two two CD cord-022526-j9kg00qf 687 15 controlling control VBG cord-022526-j9kg00qf 687 16 systems system NNS cord-022526-j9kg00qf 687 17 . . . cord-022526-j9kg00qf 688 1 34 34 CD cord-022526-j9kg00qf 689 1 Preformed preformed JJ cord-022526-j9kg00qf 689 2 inflammatory inflammatory JJ cord-022526-j9kg00qf 689 3 mediators mediator NNS cord-022526-j9kg00qf 689 4 such such JJ cord-022526-j9kg00qf 689 5 as as IN cord-022526-j9kg00qf 689 6 histamine histamine NN cord-022526-j9kg00qf 689 7 , , , cord-022526-j9kg00qf 689 8 serotonin serotonin NN cord-022526-j9kg00qf 689 9 , , , cord-022526-j9kg00qf 689 10 or or CC cord-022526-j9kg00qf 689 11 adenosine adenosine NN cord-022526-j9kg00qf 689 12 and and CC cord-022526-j9kg00qf 689 13 newly newly RB cord-022526-j9kg00qf 689 14 synthesized synthesize VBN cord-022526-j9kg00qf 689 15 mediators mediator NNS cord-022526-j9kg00qf 689 16 such such JJ cord-022526-j9kg00qf 689 17 as as IN cord-022526-j9kg00qf 689 18 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 689 19 , , , cord-022526-j9kg00qf 689 20 leukotrienes leukotriene NNS cord-022526-j9kg00qf 689 21 , , , cord-022526-j9kg00qf 689 22 platelet platelet NN cord-022526-j9kg00qf 689 23 - - HYPH cord-022526-j9kg00qf 689 24 activating activate VBG cord-022526-j9kg00qf 689 25 factor factor NN cord-022526-j9kg00qf 689 26 , , , cord-022526-j9kg00qf 689 27 various various JJ cord-022526-j9kg00qf 689 28 cytokines cytokine NNS cord-022526-j9kg00qf 689 29 , , , cord-022526-j9kg00qf 689 30 the the DT cord-022526-j9kg00qf 689 31 inducible inducible JJ cord-022526-j9kg00qf 689 32 form form NN cord-022526-j9kg00qf 689 33 of of IN cord-022526-j9kg00qf 689 34 nitric nitric NN cord-022526-j9kg00qf 689 35 oxide oxide NN cord-022526-j9kg00qf 689 36 , , , cord-022526-j9kg00qf 689 37 and and CC cord-022526-j9kg00qf 689 38 reactive reactive JJ cord-022526-j9kg00qf 689 39 oxygen oxygen NN cord-022526-j9kg00qf 689 40 metabolites metabolite NNS cord-022526-j9kg00qf 689 41 can can MD cord-022526-j9kg00qf 689 42 initiate initiate VB cord-022526-j9kg00qf 689 43 intestinal intestinal JJ cord-022526-j9kg00qf 689 44 secretion secretion NN cord-022526-j9kg00qf 689 45 by by IN cord-022526-j9kg00qf 689 46 directly directly RB cord-022526-j9kg00qf 689 47 stimulating stimulate VBG cord-022526-j9kg00qf 689 48 the the DT cord-022526-j9kg00qf 689 49 enterocyte enterocyte NN cord-022526-j9kg00qf 689 50 and and CC cord-022526-j9kg00qf 689 51 by by IN cord-022526-j9kg00qf 689 52 acting act VBG cord-022526-j9kg00qf 689 53 on on IN cord-022526-j9kg00qf 689 54 enteric enteric JJ cord-022526-j9kg00qf 689 55 nerves nerve NNS cord-022526-j9kg00qf 689 56 indirectly indirectly RB cord-022526-j9kg00qf 689 57 to to TO cord-022526-j9kg00qf 689 58 induce induce VB cord-022526-j9kg00qf 689 59 neurotransmitter neurotransmitter NN cord-022526-j9kg00qf 689 60 - - HYPH cord-022526-j9kg00qf 689 61 mediator mediator NN cord-022526-j9kg00qf 689 62 intestinal intestinal JJ cord-022526-j9kg00qf 689 63 secretion secretion NN cord-022526-j9kg00qf 689 64 . . . cord-022526-j9kg00qf 690 1 30 30 CD cord-022526-j9kg00qf 691 1 For for IN cord-022526-j9kg00qf 691 2 instance instance NN cord-022526-j9kg00qf 691 3 , , , cord-022526-j9kg00qf 691 4 when when WRB cord-022526-j9kg00qf 691 5 added add VBN cord-022526-j9kg00qf 691 6 to to IN cord-022526-j9kg00qf 691 7 the the DT cord-022526-j9kg00qf 691 8 T84 T84 NNP cord-022526-j9kg00qf 691 9 colonic colonic JJ cord-022526-j9kg00qf 691 10 cell cell NN cord-022526-j9kg00qf 691 11 line line NN cord-022526-j9kg00qf 691 12 , , , cord-022526-j9kg00qf 691 13 the the DT cord-022526-j9kg00qf 691 14 known know VBN cord-022526-j9kg00qf 691 15 mast mast NN cord-022526-j9kg00qf 691 16 cell cell NN cord-022526-j9kg00qf 691 17 mediators mediator NNS cord-022526-j9kg00qf 691 18 histamine histamine NN cord-022526-j9kg00qf 691 19 , , , cord-022526-j9kg00qf 691 20 adenosine adenosine NN cord-022526-j9kg00qf 691 21 , , , cord-022526-j9kg00qf 691 22 and and CC cord-022526-j9kg00qf 691 23 PGD PGD NNP cord-022526-j9kg00qf 691 24 2 2 CD cord-022526-j9kg00qf 691 25 induce induce VBP cord-022526-j9kg00qf 691 26 chloride chloride NN cord-022526-j9kg00qf 691 27 secretion secretion NN cord-022526-j9kg00qf 691 28 . . . cord-022526-j9kg00qf 692 1 [ [ -LRB- cord-022526-j9kg00qf 692 2 35 35 CD cord-022526-j9kg00qf 692 3 ] ] -RRB- cord-022526-j9kg00qf 692 4 [ [ -LRB- cord-022526-j9kg00qf 692 5 36 36 CD cord-022526-j9kg00qf 692 6 ] ] -RRB- cord-022526-j9kg00qf 693 1 [ [ -LRB- cord-022526-j9kg00qf 693 2 37 37 CD cord-022526-j9kg00qf 693 3 ] ] -RRB- cord-022526-j9kg00qf 693 4 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 693 5 of of IN cord-022526-j9kg00qf 693 6 the the DT cord-022526-j9kg00qf 693 7 E e NN cord-022526-j9kg00qf 693 8 and and CC cord-022526-j9kg00qf 693 9 F F NNP cord-022526-j9kg00qf 693 10 series series NN cord-022526-j9kg00qf 693 11 can can MD cord-022526-j9kg00qf 693 12 cause cause VB cord-022526-j9kg00qf 693 13 an an DT cord-022526-j9kg00qf 693 14 increase increase NN cord-022526-j9kg00qf 693 15 in in IN cord-022526-j9kg00qf 693 16 chloride chloride NN cord-022526-j9kg00qf 693 17 secretion secretion NN cord-022526-j9kg00qf 693 18 in in IN cord-022526-j9kg00qf 693 19 intact intact JJ cord-022526-j9kg00qf 693 20 tissue tissue NN cord-022526-j9kg00qf 693 21 and and CC cord-022526-j9kg00qf 693 22 isolated isolated JJ cord-022526-j9kg00qf 693 23 colonic colonic JJ cord-022526-j9kg00qf 693 24 cells cell NNS cord-022526-j9kg00qf 693 25 . . . cord-022526-j9kg00qf 694 1 [ [ -LRB- cord-022526-j9kg00qf 694 2 38 38 CD cord-022526-j9kg00qf 694 3 ] ] -RRB- cord-022526-j9kg00qf 694 4 [ [ -LRB- cord-022526-j9kg00qf 694 5 39 39 CD cord-022526-j9kg00qf 694 6 ] ] -RRB- cord-022526-j9kg00qf 695 1 [ [ -LRB- cord-022526-j9kg00qf 695 2 40 40 CD cord-022526-j9kg00qf 695 3 ] ] -RRB- cord-022526-j9kg00qf 695 4 Leukotrienes leukotriene NNS cord-022526-j9kg00qf 695 5 , , , cord-022526-j9kg00qf 695 6 platelet platelet NN cord-022526-j9kg00qf 695 7 - - HYPH cord-022526-j9kg00qf 695 8 activating activate VBG cord-022526-j9kg00qf 695 9 factor factor NN cord-022526-j9kg00qf 695 10 , , , cord-022526-j9kg00qf 695 11 and and CC cord-022526-j9kg00qf 695 12 a a DT cord-022526-j9kg00qf 695 13 number number NN cord-022526-j9kg00qf 695 14 of of IN cord-022526-j9kg00qf 695 15 cytokines cytokine NNS cord-022526-j9kg00qf 695 16 have have VBP cord-022526-j9kg00qf 695 17 been be VBN cord-022526-j9kg00qf 695 18 shown show VBN cord-022526-j9kg00qf 695 19 to to TO cord-022526-j9kg00qf 695 20 have have VB cord-022526-j9kg00qf 695 21 no no DT cord-022526-j9kg00qf 695 22 effect effect NN cord-022526-j9kg00qf 695 23 on on IN cord-022526-j9kg00qf 695 24 T84 T84 NNP cord-022526-j9kg00qf 695 25 cell cell NN cord-022526-j9kg00qf 695 26 secretion secretion NN cord-022526-j9kg00qf 695 27 but but CC cord-022526-j9kg00qf 695 28 have have VBP cord-022526-j9kg00qf 695 29 a a DT cord-022526-j9kg00qf 695 30 significant significant JJ cord-022526-j9kg00qf 695 31 effect effect NN cord-022526-j9kg00qf 695 32 on on IN cord-022526-j9kg00qf 695 33 electrolyte electrolyte JJ cord-022526-j9kg00qf 695 34 transport transport NN cord-022526-j9kg00qf 695 35 in in IN cord-022526-j9kg00qf 695 36 intact intact JJ cord-022526-j9kg00qf 695 37 tissue tissue NN cord-022526-j9kg00qf 695 38 , , , cord-022526-j9kg00qf 695 39 suggesting suggest VBG cord-022526-j9kg00qf 695 40 that that IN cord-022526-j9kg00qf 695 41 intermediate intermediate JJ cord-022526-j9kg00qf 695 42 cell cell NN cord-022526-j9kg00qf 695 43 types type NNS cord-022526-j9kg00qf 695 44 may may MD cord-022526-j9kg00qf 695 45 be be VB cord-022526-j9kg00qf 695 46 involved involve VBN cord-022526-j9kg00qf 695 47 in in IN cord-022526-j9kg00qf 695 48 these these DT cord-022526-j9kg00qf 695 49 secretory secretory JJ cord-022526-j9kg00qf 695 50 responses response NNS cord-022526-j9kg00qf 695 51 . . . cord-022526-j9kg00qf 696 1 [ [ -LRB- cord-022526-j9kg00qf 696 2 41 41 CD cord-022526-j9kg00qf 696 3 ] ] -RRB- cord-022526-j9kg00qf 696 4 [ [ -LRB- cord-022526-j9kg00qf 696 5 42 42 CD cord-022526-j9kg00qf 696 6 ] ] -RRB- cord-022526-j9kg00qf 696 7 [ [ -LRB- cord-022526-j9kg00qf 696 8 43 43 CD cord-022526-j9kg00qf 696 9 ] ] -RRB- cord-022526-j9kg00qf 697 1 The the DT cord-022526-j9kg00qf 697 2 epithelial epithelial JJ cord-022526-j9kg00qf 697 3 cell cell NN cord-022526-j9kg00qf 697 4 chloride chloride NN cord-022526-j9kg00qf 697 5 secretory secretory JJ cord-022526-j9kg00qf 697 6 response response NN cord-022526-j9kg00qf 697 7 occurs occur VBZ cord-022526-j9kg00qf 697 8 via via IN cord-022526-j9kg00qf 697 9 prostaglandin prostaglandin NN cord-022526-j9kg00qf 697 10 - - HYPH cord-022526-j9kg00qf 697 11 and and CC cord-022526-j9kg00qf 697 12 adenosine adenosine NN cord-022526-j9kg00qf 697 13 - - HYPH cord-022526-j9kg00qf 697 14 mediated mediate VBN cord-022526-j9kg00qf 697 15 increases increase NNS cord-022526-j9kg00qf 697 16 in in IN cord-022526-j9kg00qf 697 17 cellular cellular JJ cord-022526-j9kg00qf 697 18 cAMP camp NN cord-022526-j9kg00qf 697 19 , , , cord-022526-j9kg00qf 697 20 whereas whereas IN cord-022526-j9kg00qf 697 21 histamine histamine NN cord-022526-j9kg00qf 697 22 acts act NNS cord-022526-j9kg00qf 697 23 by by IN cord-022526-j9kg00qf 697 24 H H NNP cord-022526-j9kg00qf 697 25 1 1 CD cord-022526-j9kg00qf 697 26 receptor receptor NN cord-022526-j9kg00qf 697 27 induction induction NN cord-022526-j9kg00qf 697 28 of of IN cord-022526-j9kg00qf 697 29 phosphatidylinositol phosphatidylinositol JJ cord-022526-j9kg00qf 697 30 turnover turnover NN cord-022526-j9kg00qf 697 31 , , , cord-022526-j9kg00qf 697 32 production production NN cord-022526-j9kg00qf 697 33 of of IN cord-022526-j9kg00qf 697 34 inositol inositol NN cord-022526-j9kg00qf 697 35 triphosphate triphosphate NN cord-022526-j9kg00qf 697 36 , , , cord-022526-j9kg00qf 697 37 and and CC cord-022526-j9kg00qf 697 38 mobilization mobilization NN cord-022526-j9kg00qf 697 39 of of IN cord-022526-j9kg00qf 697 40 intracellular intracellular JJ cord-022526-j9kg00qf 697 41 calcium calcium NN cord-022526-j9kg00qf 697 42 stores store NNS cord-022526-j9kg00qf 697 43 . . . cord-022526-j9kg00qf 698 1 30 30 CD cord-022526-j9kg00qf 698 2 , , , cord-022526-j9kg00qf 698 3 33 33 CD cord-022526-j9kg00qf 698 4 Lipoxygenase Lipoxygenase NNP cord-022526-j9kg00qf 698 5 products product NNS cord-022526-j9kg00qf 698 6 ( ( -LRB- cord-022526-j9kg00qf 698 7 leukotrienes leukotriene NNS cord-022526-j9kg00qf 698 8 ) ) -RRB- cord-022526-j9kg00qf 698 9 are be VBP cord-022526-j9kg00qf 698 10 capable capable JJ cord-022526-j9kg00qf 698 11 of of IN cord-022526-j9kg00qf 698 12 activating activate VBG cord-022526-j9kg00qf 698 13 a a DT cord-022526-j9kg00qf 698 14 colonic colonic JJ cord-022526-j9kg00qf 698 15 secretory secretory JJ cord-022526-j9kg00qf 698 16 response response NN cord-022526-j9kg00qf 698 17 and and CC cord-022526-j9kg00qf 698 18 do do VBP cord-022526-j9kg00qf 698 19 not not RB cord-022526-j9kg00qf 698 20 appear appear VB cord-022526-j9kg00qf 698 21 to to TO cord-022526-j9kg00qf 698 22 involve involve VB cord-022526-j9kg00qf 698 23 the the DT cord-022526-j9kg00qf 698 24 cyclic cyclic JJ cord-022526-j9kg00qf 698 25 nucleotides nucleotide NNS cord-022526-j9kg00qf 698 26 or or CC cord-022526-j9kg00qf 698 27 calcium calcium NN cord-022526-j9kg00qf 698 28 ions ion NNS cord-022526-j9kg00qf 698 29 . . . cord-022526-j9kg00qf 699 1 41 41 CD cord-022526-j9kg00qf 699 2 Phagocyte Phagocyte NNP cord-022526-j9kg00qf 699 3 - - HYPH cord-022526-j9kg00qf 699 4 derived derive VBN cord-022526-j9kg00qf 699 5 reactive reactive JJ cord-022526-j9kg00qf 699 6 oxygen oxygen NN cord-022526-j9kg00qf 699 7 mediators mediator NNS cord-022526-j9kg00qf 699 8 ( ( -LRB- cord-022526-j9kg00qf 699 9 ROMs rom NNS cord-022526-j9kg00qf 699 10 ) ) -RRB- cord-022526-j9kg00qf 699 11 can can MD cord-022526-j9kg00qf 699 12 induce induce VB cord-022526-j9kg00qf 699 13 colonic colonic JJ cord-022526-j9kg00qf 699 14 electrolyte electrolyte JJ cord-022526-j9kg00qf 699 15 secretion secretion NN cord-022526-j9kg00qf 699 16 in in IN cord-022526-j9kg00qf 699 17 vitro vitro FW cord-022526-j9kg00qf 699 18 , , , cord-022526-j9kg00qf 699 19 suggesting suggest VBG cord-022526-j9kg00qf 699 20 that that IN cord-022526-j9kg00qf 699 21 oxidants oxidant NNS cord-022526-j9kg00qf 699 22 may may MD cord-022526-j9kg00qf 699 23 contribute contribute VB cord-022526-j9kg00qf 699 24 directly directly RB cord-022526-j9kg00qf 699 25 to to IN cord-022526-j9kg00qf 699 26 the the DT cord-022526-j9kg00qf 699 27 diarrhea diarrhea NN cord-022526-j9kg00qf 699 28 associated associate VBN cord-022526-j9kg00qf 699 29 with with IN cord-022526-j9kg00qf 699 30 colitis colitis NN cord-022526-j9kg00qf 699 31 . . . cord-022526-j9kg00qf 700 1 [ [ -LRB- cord-022526-j9kg00qf 700 2 44 44 CD cord-022526-j9kg00qf 700 3 ] ] -RRB- cord-022526-j9kg00qf 700 4 [ [ -LRB- cord-022526-j9kg00qf 700 5 45 45 CD cord-022526-j9kg00qf 700 6 ] ] -RRB- cord-022526-j9kg00qf 701 1 [ [ -LRB- cord-022526-j9kg00qf 701 2 46 46 CD cord-022526-j9kg00qf 701 3 ] ] -RRB- cord-022526-j9kg00qf 702 1 [ [ -LRB- cord-022526-j9kg00qf 702 2 47 47 CD cord-022526-j9kg00qf 702 3 ] ] -RRB- cord-022526-j9kg00qf 702 4 [ [ -LRB- cord-022526-j9kg00qf 702 5 48 48 CD cord-022526-j9kg00qf 702 6 ] ] -RRB- cord-022526-j9kg00qf 703 1 Reactive reactive JJ cord-022526-j9kg00qf 703 2 oxygen oxygen NN cord-022526-j9kg00qf 703 3 species specie NNS cord-022526-j9kg00qf 703 4 initiate initiate VBP cord-022526-j9kg00qf 703 5 the the DT cord-022526-j9kg00qf 703 6 secretory secretory JJ cord-022526-j9kg00qf 703 7 response response NN cord-022526-j9kg00qf 703 8 by by IN cord-022526-j9kg00qf 703 9 increasing increase VBG cord-022526-j9kg00qf 703 10 cellular cellular JJ cord-022526-j9kg00qf 703 11 cAMP camp NN cord-022526-j9kg00qf 703 12 or or CC cord-022526-j9kg00qf 703 13 stimulating stimulate VBG cord-022526-j9kg00qf 703 14 mesenchymal mesenchymal JJ cord-022526-j9kg00qf 703 15 release release NN cord-022526-j9kg00qf 703 16 of of IN cord-022526-j9kg00qf 703 17 PGE PGE NNP cord-022526-j9kg00qf 703 18 2 2 CD cord-022526-j9kg00qf 703 19 or or CC cord-022526-j9kg00qf 703 20 prostacyclin prostacyclin NNP cord-022526-j9kg00qf 703 21 , , , cord-022526-j9kg00qf 703 22 which which WDT cord-022526-j9kg00qf 703 23 in in IN cord-022526-j9kg00qf 703 24 turn turn NN cord-022526-j9kg00qf 703 25 stimulates stimulate VBZ cord-022526-j9kg00qf 703 26 the the DT cord-022526-j9kg00qf 703 27 epithelial epithelial JJ cord-022526-j9kg00qf 703 28 cell cell NN cord-022526-j9kg00qf 703 29 or or CC cord-022526-j9kg00qf 703 30 enteric enteric JJ cord-022526-j9kg00qf 703 31 neuron neuron NN cord-022526-j9kg00qf 703 32 , , , cord-022526-j9kg00qf 703 33 respectively respectively RB cord-022526-j9kg00qf 703 34 . . . cord-022526-j9kg00qf 704 1 [ [ -LRB- cord-022526-j9kg00qf 704 2 44 44 CD cord-022526-j9kg00qf 704 3 ] ] -RRB- cord-022526-j9kg00qf 704 4 [ [ -LRB- cord-022526-j9kg00qf 704 5 45 45 CD cord-022526-j9kg00qf 704 6 ] ] -RRB- cord-022526-j9kg00qf 705 1 [ [ -LRB- cord-022526-j9kg00qf 705 2 46 46 CD cord-022526-j9kg00qf 705 3 ] ] -RRB- cord-022526-j9kg00qf 706 1 [ [ -LRB- cord-022526-j9kg00qf 706 2 47 47 CD cord-022526-j9kg00qf 706 3 ] ] -RRB- cord-022526-j9kg00qf 707 1 [ [ -LRB- cord-022526-j9kg00qf 707 2 48 48 CD cord-022526-j9kg00qf 707 3 ] ] -RRB- cord-022526-j9kg00qf 707 4 [ [ -LRB- cord-022526-j9kg00qf 707 5 49 49 CD cord-022526-j9kg00qf 707 6 ] ] -RRB- cord-022526-j9kg00qf 708 1 Sodium sodium NN cord-022526-j9kg00qf 708 2 nitroprusside nitroprusside RB cord-022526-j9kg00qf 708 3 , , , cord-022526-j9kg00qf 708 4 an an DT cord-022526-j9kg00qf 708 5 exogenous exogenous JJ cord-022526-j9kg00qf 708 6 source source NN cord-022526-j9kg00qf 708 7 of of IN cord-022526-j9kg00qf 708 8 nitric nitric NN cord-022526-j9kg00qf 708 9 oxide oxide NN cord-022526-j9kg00qf 708 10 , , , cord-022526-j9kg00qf 708 11 stimulated stimulate VBD cord-022526-j9kg00qf 708 12 an an DT cord-022526-j9kg00qf 708 13 increase increase NN cord-022526-j9kg00qf 708 14 in in IN cord-022526-j9kg00qf 708 15 chloride chloride NN cord-022526-j9kg00qf 708 16 secretion secretion NN cord-022526-j9kg00qf 708 17 in in IN cord-022526-j9kg00qf 708 18 rat rat NN cord-022526-j9kg00qf 708 19 colon colon NN cord-022526-j9kg00qf 708 20 that that WDT cord-022526-j9kg00qf 708 21 was be VBD cord-022526-j9kg00qf 708 22 mediated mediate VBN cord-022526-j9kg00qf 708 23 by by IN cord-022526-j9kg00qf 708 24 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 708 25 products product NNS cord-022526-j9kg00qf 708 26 and and CC cord-022526-j9kg00qf 708 27 enteric enteric JJ cord-022526-j9kg00qf 708 28 neurons neuron NNS cord-022526-j9kg00qf 708 29 . . . cord-022526-j9kg00qf 709 1 50 50 CD cord-022526-j9kg00qf 709 2 Table table NN cord-022526-j9kg00qf 709 3 13 13 CD cord-022526-j9kg00qf 709 4 .3 .3 CD cord-022526-j9kg00qf 709 5 - - SYM cord-022526-j9kg00qf 709 6 1 1 CD cord-022526-j9kg00qf 709 7 summarizes summarize VBZ cord-022526-j9kg00qf 709 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 709 9 mediator mediator NN cord-022526-j9kg00qf 709 10 - - HYPH cord-022526-j9kg00qf 709 11 induced induce VBN cord-022526-j9kg00qf 709 12 epithelial epithelial JJ cord-022526-j9kg00qf 709 13 cell cell NN cord-022526-j9kg00qf 709 14 chloride chloride NN cord-022526-j9kg00qf 709 15 secretion secretion NN cord-022526-j9kg00qf 709 16 . . . cord-022526-j9kg00qf 710 1 Acute acute JJ cord-022526-j9kg00qf 710 2 colitis colitis NN cord-022526-j9kg00qf 710 3 rarely rarely RB cord-022526-j9kg00qf 710 4 develops develop VBZ cord-022526-j9kg00qf 710 5 by by IN cord-022526-j9kg00qf 710 6 a a DT cord-022526-j9kg00qf 710 7 simple simple JJ cord-022526-j9kg00qf 710 8 cause cause NN cord-022526-j9kg00qf 710 9 or or CC cord-022526-j9kg00qf 710 10 effect effect NN cord-022526-j9kg00qf 710 11 phenomenon phenomenon NN cord-022526-j9kg00qf 710 12 but but CC cord-022526-j9kg00qf 710 13 is be VBZ cord-022526-j9kg00qf 710 14 influenced influence VBN cord-022526-j9kg00qf 710 15 by by IN cord-022526-j9kg00qf 710 16 many many JJ cord-022526-j9kg00qf 710 17 extrinsic extrinsic JJ cord-022526-j9kg00qf 710 18 and and CC cord-022526-j9kg00qf 710 19 intrinsic intrinsic JJ cord-022526-j9kg00qf 710 20 host host NN cord-022526-j9kg00qf 710 21 and and CC cord-022526-j9kg00qf 710 22 microorganism microorganism NN cord-022526-j9kg00qf 710 23 factors factor NNS cord-022526-j9kg00qf 710 24 . . . cord-022526-j9kg00qf 711 1 Inflammatory inflammatory JJ cord-022526-j9kg00qf 711 2 mediators mediator NNS cord-022526-j9kg00qf 711 3 released release VBN cord-022526-j9kg00qf 711 4 from from IN cord-022526-j9kg00qf 711 5 mast mast NN cord-022526-j9kg00qf 711 6 cells cell NNS cord-022526-j9kg00qf 711 7 and and CC cord-022526-j9kg00qf 711 8 monocytic monocytic JJ cord-022526-j9kg00qf 711 9 or or CC cord-022526-j9kg00qf 711 10 granulocytic granulocytic JJ cord-022526-j9kg00qf 711 11 phagocytes phagocyte NNS cord-022526-j9kg00qf 711 12 cause cause VBP cord-022526-j9kg00qf 711 13 intestinal intestinal JJ cord-022526-j9kg00qf 711 14 chloride chloride NN cord-022526-j9kg00qf 711 15 and and CC cord-022526-j9kg00qf 711 16 water water NN cord-022526-j9kg00qf 711 17 secretion secretion NN cord-022526-j9kg00qf 711 18 and and CC cord-022526-j9kg00qf 711 19 inhibit inhibit VB cord-022526-j9kg00qf 711 20 neutral neutral JJ cord-022526-j9kg00qf 711 21 sodium sodium NN cord-022526-j9kg00qf 711 22 and and CC cord-022526-j9kg00qf 711 23 chloride chloride NN cord-022526-j9kg00qf 711 24 absorption absorption NN cord-022526-j9kg00qf 711 25 . . . cord-022526-j9kg00qf 712 1 29 29 CD cord-022526-j9kg00qf 712 2 , , , cord-022526-j9kg00qf 712 3 30 30 CD cord-022526-j9kg00qf 712 4 , , , cord-022526-j9kg00qf 712 5 67 67 CD cord-022526-j9kg00qf 712 6 Inflammatory inflammatory JJ cord-022526-j9kg00qf 712 7 cells cell NNS cord-022526-j9kg00qf 712 8 , , , cord-022526-j9kg00qf 712 9 particularly particularly RB cord-022526-j9kg00qf 712 10 the the DT cord-022526-j9kg00qf 712 11 phagocytic phagocytic JJ cord-022526-j9kg00qf 712 12 granulocytes granulocyte NNS cord-022526-j9kg00qf 712 13 , , , cord-022526-j9kg00qf 712 14 play play VBP cord-022526-j9kg00qf 712 15 an an DT cord-022526-j9kg00qf 712 16 important important JJ cord-022526-j9kg00qf 712 17 role role NN cord-022526-j9kg00qf 712 18 in in IN cord-022526-j9kg00qf 712 19 mucosal mucosal JJ cord-022526-j9kg00qf 712 20 pathophysiology pathophysiology NN cord-022526-j9kg00qf 712 21 in in IN cord-022526-j9kg00qf 712 22 cases case NNS cord-022526-j9kg00qf 712 23 of of IN cord-022526-j9kg00qf 712 24 colitis colitis NN cord-022526-j9kg00qf 712 25 . . . cord-022526-j9kg00qf 713 1 20 20 CD cord-022526-j9kg00qf 713 2 , , , cord-022526-j9kg00qf 713 3 68 68 CD cord-022526-j9kg00qf 713 4 Large large JJ cord-022526-j9kg00qf 713 5 numbers number NNS cord-022526-j9kg00qf 713 6 of of IN cord-022526-j9kg00qf 713 7 these these DT cord-022526-j9kg00qf 713 8 cells cell NNS cord-022526-j9kg00qf 713 9 are be VBP cord-022526-j9kg00qf 713 10 observed observe VBN cord-022526-j9kg00qf 713 11 on on IN cord-022526-j9kg00qf 713 12 histopathologic histopathologic JJ cord-022526-j9kg00qf 713 13 examination examination NN cord-022526-j9kg00qf 713 14 of of IN cord-022526-j9kg00qf 713 15 tissues tissue NNS cord-022526-j9kg00qf 713 16 from from IN cord-022526-j9kg00qf 713 17 human human JJ cord-022526-j9kg00qf 713 18 and and CC cord-022526-j9kg00qf 713 19 animal animal NN cord-022526-j9kg00qf 713 20 cases case NNS cord-022526-j9kg00qf 713 21 of of IN cord-022526-j9kg00qf 713 22 colitis colitis NN cord-022526-j9kg00qf 713 23 . . . cord-022526-j9kg00qf 714 1 Products product NNS cord-022526-j9kg00qf 714 2 of of IN cord-022526-j9kg00qf 714 3 cell cell NN cord-022526-j9kg00qf 714 4 activation activation NN cord-022526-j9kg00qf 714 5 stimulate stimulate VBP cord-022526-j9kg00qf 714 6 direct direct JJ cord-022526-j9kg00qf 714 7 and and CC cord-022526-j9kg00qf 714 8 indirect indirect JJ cord-022526-j9kg00qf 714 9 secretory secretory JJ cord-022526-j9kg00qf 714 10 responses response NNS cord-022526-j9kg00qf 714 11 in in IN cord-022526-j9kg00qf 714 12 intestinal intestinal JJ cord-022526-j9kg00qf 714 13 cells cell NNS cord-022526-j9kg00qf 714 14 and and CC cord-022526-j9kg00qf 714 15 tissues tissue NNS cord-022526-j9kg00qf 714 16 . . . cord-022526-j9kg00qf 715 1 [ [ -LRB- cord-022526-j9kg00qf 715 2 28 28 CD cord-022526-j9kg00qf 715 3 ] ] -RRB- cord-022526-j9kg00qf 715 4 [ [ -LRB- cord-022526-j9kg00qf 715 5 29 29 CD cord-022526-j9kg00qf 715 6 ] ] -RRB- cord-022526-j9kg00qf 716 1 [ [ -LRB- cord-022526-j9kg00qf 716 2 30 30 CD cord-022526-j9kg00qf 716 3 ] ] -RRB- cord-022526-j9kg00qf 716 4 [ [ -LRB- cord-022526-j9kg00qf 716 5 45 45 CD cord-022526-j9kg00qf 716 6 ] ] -RRB- cord-022526-j9kg00qf 717 1 [ [ -LRB- cord-022526-j9kg00qf 717 2 46 46 CD cord-022526-j9kg00qf 717 3 ] ] -RRB- cord-022526-j9kg00qf 718 1 [ [ -LRB- cord-022526-j9kg00qf 718 2 47 47 CD cord-022526-j9kg00qf 718 3 ] ] -RRB- cord-022526-j9kg00qf 719 1 [ [ -LRB- cord-022526-j9kg00qf 719 2 48 48 CD cord-022526-j9kg00qf 719 3 ] ] -RRB- cord-022526-j9kg00qf 720 1 [ [ -LRB- cord-022526-j9kg00qf 720 2 49 49 CD cord-022526-j9kg00qf 720 3 ] ] -RRB- cord-022526-j9kg00qf 720 4 Products Products NNPS cord-022526-j9kg00qf 720 5 of of IN cord-022526-j9kg00qf 720 6 phagocyte phagocyte NNP cord-022526-j9kg00qf 720 7 secretion secretion NN cord-022526-j9kg00qf 720 8 may may MD cord-022526-j9kg00qf 720 9 amplify amplify VB cord-022526-j9kg00qf 720 10 the the DT cord-022526-j9kg00qf 720 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 720 12 signal signal NN cord-022526-j9kg00qf 720 13 or or CC cord-022526-j9kg00qf 720 14 have have VBP cord-022526-j9kg00qf 720 15 effects effect NNS cord-022526-j9kg00qf 720 16 on on IN cord-022526-j9kg00qf 720 17 other other JJ cord-022526-j9kg00qf 720 18 target target NN cord-022526-j9kg00qf 720 19 cells cell NNS cord-022526-j9kg00qf 720 20 in in IN cord-022526-j9kg00qf 720 21 intestine intestine NN cord-022526-j9kg00qf 720 22 such such JJ cord-022526-j9kg00qf 720 23 as as IN cord-022526-j9kg00qf 720 24 enterocytes enterocyte NNS cord-022526-j9kg00qf 720 25 and and CC cord-022526-j9kg00qf 720 26 smooth smooth JJ cord-022526-j9kg00qf 720 27 muscle muscle NN cord-022526-j9kg00qf 720 28 cells cell NNS cord-022526-j9kg00qf 720 29 ( ( -LRB- cord-022526-j9kg00qf 720 30 Table table NN cord-022526-j9kg00qf 720 31 13 13 CD cord-022526-j9kg00qf 720 32 .3 .3 CD cord-022526-j9kg00qf 720 33 - - SYM cord-022526-j9kg00qf 720 34 2 2 CD cord-022526-j9kg00qf 720 35 ) ) -RRB- cord-022526-j9kg00qf 720 36 . . . cord-022526-j9kg00qf 721 1 The the DT cord-022526-j9kg00qf 721 2 NADPH nadph NN cord-022526-j9kg00qf 721 3 - - HYPH cord-022526-j9kg00qf 721 4 oxidase oxidase NN cord-022526-j9kg00qf 721 5 system system NN cord-022526-j9kg00qf 721 6 of of IN cord-022526-j9kg00qf 721 7 phagocytes phagocyte NNS cord-022526-j9kg00qf 721 8 ( ( -LRB- cord-022526-j9kg00qf 721 9 neutrophils neutrophil NNS cord-022526-j9kg00qf 721 10 , , , cord-022526-j9kg00qf 721 11 eosinophils eosinophil NNS cord-022526-j9kg00qf 721 12 , , , cord-022526-j9kg00qf 721 13 monocytes monocyte NNS cord-022526-j9kg00qf 721 14 / / SYM cord-022526-j9kg00qf 721 15 macrophages macrophage NNS cord-022526-j9kg00qf 721 16 ) ) -RRB- cord-022526-j9kg00qf 721 17 is be VBZ cord-022526-j9kg00qf 721 18 a a DT cord-022526-j9kg00qf 721 19 potent potent JJ cord-022526-j9kg00qf 721 20 inducer inducer NN cord-022526-j9kg00qf 721 21 of of IN cord-022526-j9kg00qf 721 22 superoxide superoxide NN cord-022526-j9kg00qf 721 23 radicals radical NNS cord-022526-j9kg00qf 721 24 used use VBN cord-022526-j9kg00qf 721 25 as as IN cord-022526-j9kg00qf 721 26 a a DT cord-022526-j9kg00qf 721 27 host host NN cord-022526-j9kg00qf 721 28 defense defense NN cord-022526-j9kg00qf 721 29 mechanism mechanism NN cord-022526-j9kg00qf 721 30 to to TO cord-022526-j9kg00qf 721 31 kill kill VB cord-022526-j9kg00qf 721 32 invading invade VBG cord-022526-j9kg00qf 721 33 microorganisms microorganism NNS cord-022526-j9kg00qf 721 34 . . . cord-022526-j9kg00qf 722 1 20 20 CD cord-022526-j9kg00qf 722 2 , , , cord-022526-j9kg00qf 722 3 69 69 CD cord-022526-j9kg00qf 723 1 During during IN cord-022526-j9kg00qf 723 2 inappropriate inappropriate JJ cord-022526-j9kg00qf 723 3 stimulation stimulation NN cord-022526-j9kg00qf 723 4 such such JJ cord-022526-j9kg00qf 723 5 as as IN cord-022526-j9kg00qf 723 6 inflammation inflammation NN cord-022526-j9kg00qf 723 7 , , , cord-022526-j9kg00qf 723 8 trauma trauma NN cord-022526-j9kg00qf 723 9 , , , cord-022526-j9kg00qf 723 10 or or CC cord-022526-j9kg00qf 723 11 ischemia ischemia NN cord-022526-j9kg00qf 723 12 followed follow VBN cord-022526-j9kg00qf 723 13 by by IN cord-022526-j9kg00qf 723 14 reperfusion reperfusion NN cord-022526-j9kg00qf 723 15 , , , cord-022526-j9kg00qf 723 16 increased increase VBN cord-022526-j9kg00qf 723 17 levels level NNS cord-022526-j9kg00qf 723 18 of of IN cord-022526-j9kg00qf 723 19 toxic toxic JJ cord-022526-j9kg00qf 723 20 oxygen oxygen NN cord-022526-j9kg00qf 723 21 species specie NNS cord-022526-j9kg00qf 723 22 are be VBP cord-022526-j9kg00qf 723 23 produced produce VBN cord-022526-j9kg00qf 723 24 , , , cord-022526-j9kg00qf 723 25 causing cause VBG cord-022526-j9kg00qf 723 26 damage damage NN cord-022526-j9kg00qf 723 27 to to IN cord-022526-j9kg00qf 723 28 host host NN cord-022526-j9kg00qf 723 29 tissues tissue NNS cord-022526-j9kg00qf 723 30 . . . cord-022526-j9kg00qf 724 1 Engagement engagement NN cord-022526-j9kg00qf 724 2 of of IN cord-022526-j9kg00qf 724 3 any any DT cord-022526-j9kg00qf 724 4 of of IN cord-022526-j9kg00qf 724 5 several several JJ cord-022526-j9kg00qf 724 6 receptor receptor NN cord-022526-j9kg00qf 724 7 and and CC cord-022526-j9kg00qf 724 8 nonreceptor nonreceptor NN cord-022526-j9kg00qf 724 9 types type NNS cord-022526-j9kg00qf 724 10 including include VBG cord-022526-j9kg00qf 724 11 phagocytosis phagocytosis NN cord-022526-j9kg00qf 724 12 mediators mediator NNS cord-022526-j9kg00qf 724 13 , , , cord-022526-j9kg00qf 724 14 chemotactic chemotactic JJ cord-022526-j9kg00qf 724 15 agents agent NNS cord-022526-j9kg00qf 724 16 , , , cord-022526-j9kg00qf 724 17 various various JJ cord-022526-j9kg00qf 724 18 cytokines cytokine NNS cord-022526-j9kg00qf 724 19 , , , cord-022526-j9kg00qf 724 20 and and CC cord-022526-j9kg00qf 724 21 microbial microbial JJ cord-022526-j9kg00qf 724 22 products product NNS cord-022526-j9kg00qf 724 23 can can MD cord-022526-j9kg00qf 724 24 stimulate stimulate VB cord-022526-j9kg00qf 724 25 phagocytes phagocyte NNS cord-022526-j9kg00qf 724 26 . . . cord-022526-j9kg00qf 725 1 20 20 CD cord-022526-j9kg00qf 725 2 Resident resident JJ cord-022526-j9kg00qf 725 3 phagocytes phagocyte NNS cord-022526-j9kg00qf 725 4 or or CC cord-022526-j9kg00qf 725 5 those those DT cord-022526-j9kg00qf 725 6 recruited recruit VBN cord-022526-j9kg00qf 725 7 to to IN cord-022526-j9kg00qf 725 8 colonic colonic JJ cord-022526-j9kg00qf 725 9 mucosa mucosa NNS cord-022526-j9kg00qf 725 10 early early RB cord-022526-j9kg00qf 725 11 in in IN cord-022526-j9kg00qf 725 12 the the DT cord-022526-j9kg00qf 725 13 disease disease NN cord-022526-j9kg00qf 725 14 process process NN cord-022526-j9kg00qf 725 15 are be VBP cord-022526-j9kg00qf 725 16 considered consider VBN cord-022526-j9kg00qf 725 17 to to TO cord-022526-j9kg00qf 725 18 augment augment VB cord-022526-j9kg00qf 725 19 mechanisms mechanism NNS cord-022526-j9kg00qf 725 20 causing cause VBG cord-022526-j9kg00qf 725 21 fluid fluid NN cord-022526-j9kg00qf 725 22 and and CC cord-022526-j9kg00qf 725 23 electrolyte electrolyte JJ cord-022526-j9kg00qf 725 24 secretory secretory NN cord-022526-j9kg00qf 725 25 processes process NNS cord-022526-j9kg00qf 725 26 , , , cord-022526-j9kg00qf 725 27 a a DT cord-022526-j9kg00qf 725 28 so so RB cord-022526-j9kg00qf 725 29 - - HYPH cord-022526-j9kg00qf 725 30 called call VBN cord-022526-j9kg00qf 725 31 amplification amplification NN cord-022526-j9kg00qf 725 32 process process NN cord-022526-j9kg00qf 725 33 . . . cord-022526-j9kg00qf 726 1 70 70 CD cord-022526-j9kg00qf 726 2 , , , cord-022526-j9kg00qf 726 3 71 71 CD cord-022526-j9kg00qf 726 4 Activation activation NN cord-022526-j9kg00qf 726 5 of of IN cord-022526-j9kg00qf 726 6 the the DT cord-022526-j9kg00qf 726 7 respiratory respiratory JJ cord-022526-j9kg00qf 726 8 burst burst NN cord-022526-j9kg00qf 726 9 results result NNS cord-022526-j9kg00qf 726 10 in in IN cord-022526-j9kg00qf 726 11 the the DT cord-022526-j9kg00qf 726 12 production production NN cord-022526-j9kg00qf 726 13 and and CC cord-022526-j9kg00qf 726 14 release release NN cord-022526-j9kg00qf 726 15 of of IN cord-022526-j9kg00qf 726 16 large large JJ cord-022526-j9kg00qf 726 17 amounts amount NNS cord-022526-j9kg00qf 726 18 of of IN cord-022526-j9kg00qf 726 19 superoxide superoxide NN cord-022526-j9kg00qf 726 20 anion anion NN cord-022526-j9kg00qf 726 21 ( ( -LRB- cord-022526-j9kg00qf 726 22 O o UH cord-022526-j9kg00qf 726 23 2 2 CD cord-022526-j9kg00qf 726 24 − − NNP cord-022526-j9kg00qf 726 25 ) ) -RRB- cord-022526-j9kg00qf 726 26 and and CC cord-022526-j9kg00qf 726 27 H H NNP cord-022526-j9kg00qf 726 28 2 2 CD cord-022526-j9kg00qf 726 29 O o NN cord-022526-j9kg00qf 726 30 2 2 CD cord-022526-j9kg00qf 726 31 . . . cord-022526-j9kg00qf 726 32 69 69 CD cord-022526-j9kg00qf 726 33 , , , cord-022526-j9kg00qf 726 34 72 72 CD cord-022526-j9kg00qf 727 1 In in IN cord-022526-j9kg00qf 727 2 addition addition NN cord-022526-j9kg00qf 727 3 to to IN cord-022526-j9kg00qf 727 4 these these DT cord-022526-j9kg00qf 727 5 ROMs rom NNS cord-022526-j9kg00qf 727 6 , , , cord-022526-j9kg00qf 727 7 activated activate VBN cord-022526-j9kg00qf 727 8 phagocytes phagocyte NNS cord-022526-j9kg00qf 727 9 secrete secrete VBP cord-022526-j9kg00qf 727 10 peroxidase peroxidase NN cord-022526-j9kg00qf 727 11 enzyme enzyme NN cord-022526-j9kg00qf 727 12 ( ( -LRB- cord-022526-j9kg00qf 727 13 myeloperoxidase myeloperoxidase NN cord-022526-j9kg00qf 727 14 from from IN cord-022526-j9kg00qf 727 15 neutrophils neutrophil NNS cord-022526-j9kg00qf 727 16 and and CC cord-022526-j9kg00qf 727 17 eosinophil eosinophil JJ cord-022526-j9kg00qf 727 18 peroxidase peroxidase NN cord-022526-j9kg00qf 727 19 from from IN cord-022526-j9kg00qf 727 20 eosinophils eosinophils NN cord-022526-j9kg00qf 727 21 ) ) -RRB- cord-022526-j9kg00qf 727 22 into into IN cord-022526-j9kg00qf 727 23 the the DT cord-022526-j9kg00qf 727 24 extracellular extracellular JJ cord-022526-j9kg00qf 727 25 space space NN cord-022526-j9kg00qf 727 26 . . . cord-022526-j9kg00qf 728 1 The the DT cord-022526-j9kg00qf 728 2 peroxidases peroxidase NNS cord-022526-j9kg00qf 728 3 catalyze catalyze VBP cord-022526-j9kg00qf 728 4 the the DT cord-022526-j9kg00qf 728 5 oxidation oxidation NN cord-022526-j9kg00qf 728 6 of of IN cord-022526-j9kg00qf 728 7 Clby Clby NNP cord-022526-j9kg00qf 728 8 H H NNP cord-022526-j9kg00qf 728 9 2 2 CD cord-022526-j9kg00qf 728 10 O o NN cord-022526-j9kg00qf 728 11 2 2 CD cord-022526-j9kg00qf 728 12 to to TO cord-022526-j9kg00qf 728 13 yield yield VB cord-022526-j9kg00qf 728 14 HOCl HOCl NNS cord-022526-j9kg00qf 728 15 , , , cord-022526-j9kg00qf 728 16 the the DT cord-022526-j9kg00qf 728 17 active active JJ cord-022526-j9kg00qf 728 18 ingredient ingredient NN cord-022526-j9kg00qf 728 19 in in IN cord-022526-j9kg00qf 728 20 household household NN cord-022526-j9kg00qf 728 21 bleach bleach NN cord-022526-j9kg00qf 728 22 products product NNS cord-022526-j9kg00qf 728 23 . . . cord-022526-j9kg00qf 729 1 The the DT cord-022526-j9kg00qf 729 2 peroxidase peroxidase NN cord-022526-j9kg00qf 729 3 - - HYPH cord-022526-j9kg00qf 729 4 H h NN cord-022526-j9kg00qf 729 5 2 2 CD cord-022526-j9kg00qf 730 1 O o UH cord-022526-j9kg00qf 730 2 2 2 CD cord-022526-j9kg00qf 730 3 -halide -halide JJ cord-022526-j9kg00qf 730 4 system system NN cord-022526-j9kg00qf 730 5 is be VBZ cord-022526-j9kg00qf 730 6 the the DT cord-022526-j9kg00qf 730 7 most most RBS cord-022526-j9kg00qf 730 8 cytotoxic cytotoxic JJ cord-022526-j9kg00qf 730 9 system system NN cord-022526-j9kg00qf 730 10 of of IN cord-022526-j9kg00qf 730 11 the the DT cord-022526-j9kg00qf 730 12 phagocytes phagocyte NNS cord-022526-j9kg00qf 730 13 ; ; : cord-022526-j9kg00qf 730 14 HOCl HOCl NNP cord-022526-j9kg00qf 730 15 is be VBZ cord-022526-j9kg00qf 730 16 100 100 CD cord-022526-j9kg00qf 730 17 to to TO cord-022526-j9kg00qf 730 18 1000 1000 CD cord-022526-j9kg00qf 730 19 times time NNS cord-022526-j9kg00qf 730 20 more more RBR cord-022526-j9kg00qf 730 21 toxic toxic JJ cord-022526-j9kg00qf 730 22 than than IN cord-022526-j9kg00qf 730 23 O o NN cord-022526-j9kg00qf 730 24 2 2 CD cord-022526-j9kg00qf 730 25 or or CC cord-022526-j9kg00qf 730 26 H h NN cord-022526-j9kg00qf 730 27 2 2 CD cord-022526-j9kg00qf 730 28 O o NN cord-022526-j9kg00qf 730 29 2 2 CD cord-022526-j9kg00qf 730 30 . . . cord-022526-j9kg00qf 731 1 69 69 CD cord-022526-j9kg00qf 731 2 HOCl HOCl NNS cord-022526-j9kg00qf 731 3 is be VBZ cord-022526-j9kg00qf 731 4 a a DT cord-022526-j9kg00qf 731 5 nonspecific nonspecific JJ cord-022526-j9kg00qf 731 6 oxidizing oxidizing NN cord-022526-j9kg00qf 731 7 and and CC cord-022526-j9kg00qf 731 8 chlorinating chlorinate VBG cord-022526-j9kg00qf 731 9 agent agent NN cord-022526-j9kg00qf 731 10 that that WDT cord-022526-j9kg00qf 731 11 reacts react VBZ cord-022526-j9kg00qf 731 12 rapidly rapidly RB cord-022526-j9kg00qf 731 13 with with IN cord-022526-j9kg00qf 731 14 a a DT cord-022526-j9kg00qf 731 15 variety variety NN cord-022526-j9kg00qf 731 16 of of IN cord-022526-j9kg00qf 731 17 biologic biologic JJ cord-022526-j9kg00qf 731 18 compounds compound NNS cord-022526-j9kg00qf 731 19 including include VBG cord-022526-j9kg00qf 731 20 DNA dna NN cord-022526-j9kg00qf 731 21 , , , cord-022526-j9kg00qf 731 22 sulfhydryls sulfhydryls NN cord-022526-j9kg00qf 731 23 , , , cord-022526-j9kg00qf 731 24 nucleotides nucleotide NNS cord-022526-j9kg00qf 731 25 , , , cord-022526-j9kg00qf 731 26 amino amino JJ cord-022526-j9kg00qf 731 27 acids acid NNS cord-022526-j9kg00qf 731 28 , , , cord-022526-j9kg00qf 731 29 and and CC cord-022526-j9kg00qf 731 30 other other JJ cord-022526-j9kg00qf 731 31 nitrogen nitrogen NN cord-022526-j9kg00qf 731 32 - - HYPH cord-022526-j9kg00qf 731 33 containing contain VBG cord-022526-j9kg00qf 731 34 compounds compound NNS cord-022526-j9kg00qf 731 35 . . . cord-022526-j9kg00qf 732 1 HOCl HOCl NNP cord-022526-j9kg00qf 732 2 reacts react VBZ cord-022526-j9kg00qf 732 3 rapidly rapidly RB cord-022526-j9kg00qf 732 4 with with IN cord-022526-j9kg00qf 732 5 primary primary JJ cord-022526-j9kg00qf 732 6 amines amine NNS cord-022526-j9kg00qf 732 7 ( ( -LRB- cord-022526-j9kg00qf 732 8 RNH RNH NNP cord-022526-j9kg00qf 732 9 2 2 CD cord-022526-j9kg00qf 732 10 ) ) -RRB- cord-022526-j9kg00qf 732 11 to to TO cord-022526-j9kg00qf 732 12 produce produce VB cord-022526-j9kg00qf 732 13 the the DT cord-022526-j9kg00qf 732 14 cytotoxic cytotoxic JJ cord-022526-j9kg00qf 732 15 N N NNP cord-022526-j9kg00qf 732 16 - - HYPH cord-022526-j9kg00qf 732 17 chloramines chloramine NNS cord-022526-j9kg00qf 732 18 ( ( -LRB- cord-022526-j9kg00qf 732 19 RNHCl RNHCl NNP cord-022526-j9kg00qf 732 20 ) ) -RRB- cord-022526-j9kg00qf 732 21 . . . cord-022526-j9kg00qf 733 1 The the DT cord-022526-j9kg00qf 733 2 mechanisms mechanism NNS cord-022526-j9kg00qf 733 3 by by IN cord-022526-j9kg00qf 733 4 which which WDT cord-022526-j9kg00qf 733 5 HOCl HOCl NNP cord-022526-j9kg00qf 733 6 and and CC cord-022526-j9kg00qf 733 7 RNHCl RNHCl NNP cord-022526-j9kg00qf 733 8 damage damage NN cord-022526-j9kg00qf 733 9 cells cell NNS cord-022526-j9kg00qf 733 10 and and CC cord-022526-j9kg00qf 733 11 tissue tissue NN cord-022526-j9kg00qf 733 12 remain remain VBP cord-022526-j9kg00qf 733 13 speculative speculative JJ cord-022526-j9kg00qf 733 14 , , , cord-022526-j9kg00qf 733 15 but but CC cord-022526-j9kg00qf 733 16 possibilities possibility NNS cord-022526-j9kg00qf 733 17 include include VBP cord-022526-j9kg00qf 733 18 direct direct JJ cord-022526-j9kg00qf 733 19 sulfhydryl sulfhydryl NN cord-022526-j9kg00qf 733 20 oxidation oxidation NN cord-022526-j9kg00qf 733 21 , , , cord-022526-j9kg00qf 733 22 hemoprotein hemoprotein NNP cord-022526-j9kg00qf 733 23 inactivation inactivation NN cord-022526-j9kg00qf 733 24 , , , cord-022526-j9kg00qf 733 25 protein protein NN cord-022526-j9kg00qf 733 26 and and CC cord-022526-j9kg00qf 733 27 amino amino NN cord-022526-j9kg00qf 733 28 acid acid NN cord-022526-j9kg00qf 733 29 degradation degradation NN cord-022526-j9kg00qf 733 30 , , , cord-022526-j9kg00qf 733 31 and and CC cord-022526-j9kg00qf 733 32 inactivation inactivation NN cord-022526-j9kg00qf 733 33 of of IN cord-022526-j9kg00qf 733 34 metabolic metabolic JJ cord-022526-j9kg00qf 733 35 cofactors cofactor NNS cord-022526-j9kg00qf 733 36 of of IN cord-022526-j9kg00qf 733 37 DNA dna NN cord-022526-j9kg00qf 733 38 . . . cord-022526-j9kg00qf 734 1 73 73 CD cord-022526-j9kg00qf 734 2 Peroxidase peroxidase NN cord-022526-j9kg00qf 734 3 - - HYPH cord-022526-j9kg00qf 734 4 derived derive VBN cord-022526-j9kg00qf 734 5 oxidants oxidant NNS cord-022526-j9kg00qf 734 6 have have VBP cord-022526-j9kg00qf 734 7 been be VBN cord-022526-j9kg00qf 734 8 shown show VBN cord-022526-j9kg00qf 734 9 to to TO cord-022526-j9kg00qf 734 10 degrade degrade VB cord-022526-j9kg00qf 734 11 hyaluronic hyaluronic NN cord-022526-j9kg00qf 734 12 acid acid NN cord-022526-j9kg00qf 734 13 and and CC cord-022526-j9kg00qf 734 14 collagen collagen NN cord-022526-j9kg00qf 734 15 . . . cord-022526-j9kg00qf 735 1 74 74 CD cord-022526-j9kg00qf 736 1 In in IN cord-022526-j9kg00qf 736 2 addition addition NN cord-022526-j9kg00qf 736 3 , , , cord-022526-j9kg00qf 736 4 luminal luminal JJ cord-022526-j9kg00qf 736 5 perfusion perfusion NN cord-022526-j9kg00qf 736 6 of of IN cord-022526-j9kg00qf 736 7 specific specific JJ cord-022526-j9kg00qf 736 8 ROMs rom NNS cord-022526-j9kg00qf 736 9 increased increase VBD cord-022526-j9kg00qf 736 10 mucosal mucosal JJ cord-022526-j9kg00qf 736 11 permeability permeability NN cord-022526-j9kg00qf 736 12 and and CC cord-022526-j9kg00qf 736 13 serosal serosal NN cord-022526-j9kg00qf 736 14 application application NN cord-022526-j9kg00qf 736 15 caused cause VBD cord-022526-j9kg00qf 736 16 increases increase NNS cord-022526-j9kg00qf 736 17 in in IN cord-022526-j9kg00qf 736 18 Clsecretion Clsecretion NNP cord-022526-j9kg00qf 736 19 in in IN cord-022526-j9kg00qf 736 20 vitro vitro FW cord-022526-j9kg00qf 736 21 . . . cord-022526-j9kg00qf 737 1 75 75 CD cord-022526-j9kg00qf 737 2 Tissue tissue NN cord-022526-j9kg00qf 737 3 myeloperoxidase myeloperoxidase NN cord-022526-j9kg00qf 737 4 activity activity NN cord-022526-j9kg00qf 737 5 , , , cord-022526-j9kg00qf 737 6 an an DT cord-022526-j9kg00qf 737 7 index index NN cord-022526-j9kg00qf 737 8 of of IN cord-022526-j9kg00qf 737 9 tissue tissue NN cord-022526-j9kg00qf 737 10 granulocyte granulocyte NN cord-022526-j9kg00qf 737 11 infiltration infiltration NN cord-022526-j9kg00qf 737 12 , , , cord-022526-j9kg00qf 737 13 is be VBZ cord-022526-j9kg00qf 737 14 used use VBN cord-022526-j9kg00qf 737 15 clinically clinically RB cord-022526-j9kg00qf 737 16 and and CC cord-022526-j9kg00qf 737 17 experimentally experimentally RB cord-022526-j9kg00qf 737 18 to to TO cord-022526-j9kg00qf 737 19 assess assess VB cord-022526-j9kg00qf 737 20 degree degree NN cord-022526-j9kg00qf 737 21 of of IN cord-022526-j9kg00qf 737 22 intestinal intestinal JJ cord-022526-j9kg00qf 737 23 inflammation inflammation NN cord-022526-j9kg00qf 737 24 . . . cord-022526-j9kg00qf 738 1 76 76 CD cord-022526-j9kg00qf 738 2 , , , cord-022526-j9kg00qf 738 3 77 77 CD cord-022526-j9kg00qf 738 4 Myeloperoxidase Myeloperoxidase NNP cord-022526-j9kg00qf 738 5 activity activity NN cord-022526-j9kg00qf 738 6 is be VBZ cord-022526-j9kg00qf 738 7 elevated elevate VBN cord-022526-j9kg00qf 738 8 in in IN cord-022526-j9kg00qf 738 9 acute acute JJ cord-022526-j9kg00qf 738 10 flare flare NN cord-022526-j9kg00qf 738 11 - - HYPH cord-022526-j9kg00qf 738 12 ups up NNS cord-022526-j9kg00qf 738 13 of of IN cord-022526-j9kg00qf 738 14 human human JJ cord-022526-j9kg00qf 738 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 738 16 bowel bowel NN cord-022526-j9kg00qf 738 17 disease disease NN cord-022526-j9kg00qf 738 18 and and CC cord-022526-j9kg00qf 738 19 various various JJ cord-022526-j9kg00qf 738 20 animal animal NN cord-022526-j9kg00qf 738 21 models model NNS cord-022526-j9kg00qf 738 22 of of IN cord-022526-j9kg00qf 738 23 acute acute JJ cord-022526-j9kg00qf 738 24 colitis colitis NN cord-022526-j9kg00qf 738 25 . . . cord-022526-j9kg00qf 739 1 [ [ -LRB- cord-022526-j9kg00qf 739 2 76 76 CD cord-022526-j9kg00qf 739 3 ] ] -RRB- cord-022526-j9kg00qf 739 4 [ [ -LRB- cord-022526-j9kg00qf 739 5 77 77 CD cord-022526-j9kg00qf 739 6 ] ] -RRB- cord-022526-j9kg00qf 740 1 [ [ -LRB- cord-022526-j9kg00qf 740 2 78 78 CD cord-022526-j9kg00qf 740 3 ] ] -RRB- cord-022526-j9kg00qf 740 4 [ [ -LRB- cord-022526-j9kg00qf 740 5 79 79 CD cord-022526-j9kg00qf 740 6 ] ] -RRB- cord-022526-j9kg00qf 741 1 [ [ -LRB- cord-022526-j9kg00qf 741 2 80 80 CD cord-022526-j9kg00qf 741 3 ] ] -RRB- cord-022526-j9kg00qf 742 1 The the DT cord-022526-j9kg00qf 742 2 acute acute JJ cord-022526-j9kg00qf 742 3 inflammatory inflammatory JJ cord-022526-j9kg00qf 742 4 response response NN cord-022526-j9kg00qf 742 5 in in IN cord-022526-j9kg00qf 742 6 these these DT cord-022526-j9kg00qf 742 7 conditions condition NNS cord-022526-j9kg00qf 742 8 is be VBZ cord-022526-j9kg00qf 742 9 characterized characterize VBN cord-022526-j9kg00qf 742 10 predominantly predominantly RB cord-022526-j9kg00qf 742 11 by by IN cord-022526-j9kg00qf 742 12 neutrophils neutrophil NNS cord-022526-j9kg00qf 742 13 , , , cord-022526-j9kg00qf 742 14 the the DT cord-022526-j9kg00qf 742 15 predominant predominant JJ cord-022526-j9kg00qf 742 16 source source NN cord-022526-j9kg00qf 742 17 of of IN cord-022526-j9kg00qf 742 18 myeloperoxidase myeloperoxidase NN cord-022526-j9kg00qf 742 19 activity activity NN cord-022526-j9kg00qf 742 20 . . . cord-022526-j9kg00qf 743 1 However however RB cord-022526-j9kg00qf 743 2 , , , cord-022526-j9kg00qf 743 3 this this DT cord-022526-j9kg00qf 743 4 assay assay NN cord-022526-j9kg00qf 743 5 measures measure VBZ cord-022526-j9kg00qf 743 6 total total JJ cord-022526-j9kg00qf 743 7 hemoprotein hemoprotein NNP cord-022526-j9kg00qf 743 8 peroxidase peroxidase NN cord-022526-j9kg00qf 743 9 , , , cord-022526-j9kg00qf 743 10 which which WDT cord-022526-j9kg00qf 743 11 includes include VBZ cord-022526-j9kg00qf 743 12 monocyte monocyte NNP cord-022526-j9kg00qf 743 13 and and CC cord-022526-j9kg00qf 743 14 eosinophil eosinophil JJ cord-022526-j9kg00qf 743 15 peroxidase peroxidase NN cord-022526-j9kg00qf 743 16 in in IN cord-022526-j9kg00qf 743 17 addition addition NN cord-022526-j9kg00qf 743 18 to to IN cord-022526-j9kg00qf 743 19 neutrophils neutrophil NNS cord-022526-j9kg00qf 743 20 . . . cord-022526-j9kg00qf 744 1 77 77 CD cord-022526-j9kg00qf 745 1 Moreover moreover RB cord-022526-j9kg00qf 745 2 , , , cord-022526-j9kg00qf 745 3 levels level NNS cord-022526-j9kg00qf 745 4 of of IN cord-022526-j9kg00qf 745 5 peroxidase peroxidase NN cord-022526-j9kg00qf 745 6 activity activity NN cord-022526-j9kg00qf 745 7 in in IN cord-022526-j9kg00qf 745 8 equine equine JJ cord-022526-j9kg00qf 745 9 circulating circulate VBG cord-022526-j9kg00qf 745 10 eosinophils eosinophil NNS cord-022526-j9kg00qf 745 11 are be VBP cord-022526-j9kg00qf 745 12 greater great JJR cord-022526-j9kg00qf 745 13 than than IN cord-022526-j9kg00qf 745 14 in in IN cord-022526-j9kg00qf 745 15 circulating circulate VBG cord-022526-j9kg00qf 745 16 neutrophils neutrophil NNS cord-022526-j9kg00qf 745 17 , , , cord-022526-j9kg00qf 745 18 81 81 CD cord-022526-j9kg00qf 745 19 and and CC cord-022526-j9kg00qf 745 20 this this DT cord-022526-j9kg00qf 745 21 may may MD cord-022526-j9kg00qf 745 22 apply apply VB cord-022526-j9kg00qf 745 23 to to IN cord-022526-j9kg00qf 745 24 resident resident JJ cord-022526-j9kg00qf 745 25 tissue tissue NN cord-022526-j9kg00qf 745 26 eosinophils eosinophil NNS cord-022526-j9kg00qf 745 27 as as RB cord-022526-j9kg00qf 745 28 well well RB cord-022526-j9kg00qf 745 29 . . . cord-022526-j9kg00qf 746 1 Arachidonic arachidonic JJ cord-022526-j9kg00qf 746 2 acid acid NN cord-022526-j9kg00qf 746 3 metabolites metabolite NNS cord-022526-j9kg00qf 746 4 are be VBP cord-022526-j9kg00qf 746 5 thought think VBN cord-022526-j9kg00qf 746 6 to to TO cord-022526-j9kg00qf 746 7 play play VB cord-022526-j9kg00qf 746 8 a a DT cord-022526-j9kg00qf 746 9 role role NN cord-022526-j9kg00qf 746 10 in in IN cord-022526-j9kg00qf 746 11 intestinal intestinal JJ cord-022526-j9kg00qf 746 12 inflammation inflammation NN cord-022526-j9kg00qf 746 13 in in IN cord-022526-j9kg00qf 746 14 diarrheal diarrheal JJ cord-022526-j9kg00qf 746 15 disease disease NN cord-022526-j9kg00qf 746 16 . . . cord-022526-j9kg00qf 747 1 30 30 CD cord-022526-j9kg00qf 747 2 , , , cord-022526-j9kg00qf 747 3 45 45 CD cord-022526-j9kg00qf 747 4 , , , cord-022526-j9kg00qf 747 5 82 82 CD cord-022526-j9kg00qf 747 6 Elevated elevated JJ cord-022526-j9kg00qf 747 7 levels level NNS cord-022526-j9kg00qf 747 8 of of IN cord-022526-j9kg00qf 747 9 these these DT cord-022526-j9kg00qf 747 10 intermediate intermediate JJ cord-022526-j9kg00qf 747 11 metabolites metabolite NNS cord-022526-j9kg00qf 747 12 have have VBP cord-022526-j9kg00qf 747 13 been be VBN cord-022526-j9kg00qf 747 14 demonstrated demonstrate VBN cord-022526-j9kg00qf 747 15 in in IN cord-022526-j9kg00qf 747 16 natural natural JJ cord-022526-j9kg00qf 747 17 disease disease NN cord-022526-j9kg00qf 747 18 and and CC cord-022526-j9kg00qf 747 19 experimental experimental JJ cord-022526-j9kg00qf 747 20 models model NNS cord-022526-j9kg00qf 747 21 of of IN cord-022526-j9kg00qf 747 22 colitis colitis NN cord-022526-j9kg00qf 747 23 and and CC cord-022526-j9kg00qf 747 24 appear appear VBP cord-022526-j9kg00qf 747 25 to to IN cord-022526-j9kg00qf 747 26 parallel parallel JJ cord-022526-j9kg00qf 747 27 increases increase NNS cord-022526-j9kg00qf 747 28 in in IN cord-022526-j9kg00qf 747 29 ROMs rom NNS cord-022526-j9kg00qf 747 30 in in IN cord-022526-j9kg00qf 747 31 inflamed inflamed JJ cord-022526-j9kg00qf 747 32 intestine intestine NN cord-022526-j9kg00qf 747 33 . . . cord-022526-j9kg00qf 748 1 82 82 CD cord-022526-j9kg00qf 749 1 Addition addition NN cord-022526-j9kg00qf 749 2 of of IN cord-022526-j9kg00qf 749 3 H H NNP cord-022526-j9kg00qf 749 4 2 2 CD cord-022526-j9kg00qf 749 5 O o NN cord-022526-j9kg00qf 749 6 2 2 CD cord-022526-j9kg00qf 749 7 or or CC cord-022526-j9kg00qf 749 8 HOCl HOCl NNS cord-022526-j9kg00qf 749 9 to to IN cord-022526-j9kg00qf 749 10 rat rat NN cord-022526-j9kg00qf 749 11 colonic colonic JJ cord-022526-j9kg00qf 749 12 tissue tissue NN cord-022526-j9kg00qf 749 13 in in IN cord-022526-j9kg00qf 749 14 Ussing Ussing NNP cord-022526-j9kg00qf 749 15 chambers chamber NNS cord-022526-j9kg00qf 749 16 has have VBZ cord-022526-j9kg00qf 749 17 been be VBN cord-022526-j9kg00qf 749 18 shown show VBN cord-022526-j9kg00qf 749 19 to to TO cord-022526-j9kg00qf 749 20 induce induce VB cord-022526-j9kg00qf 749 21 PGE PGE NNP cord-022526-j9kg00qf 749 22 2 2 CD cord-022526-j9kg00qf 749 23 release release NN cord-022526-j9kg00qf 749 24 and and CC cord-022526-j9kg00qf 749 25 active active JJ cord-022526-j9kg00qf 749 26 Clsecretion Clsecretion NNP cord-022526-j9kg00qf 749 27 . . . cord-022526-j9kg00qf 750 1 47 47 CD cord-022526-j9kg00qf 750 2 , , , cord-022526-j9kg00qf 750 3 48 48 CD cord-022526-j9kg00qf 750 4 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 750 5 can can MD cord-022526-j9kg00qf 750 6 stimulate stimulate VB cord-022526-j9kg00qf 750 7 increases increase NNS cord-022526-j9kg00qf 750 8 in in IN cord-022526-j9kg00qf 750 9 Clsecretion Clsecretion NNP cord-022526-j9kg00qf 750 10 in in IN cord-022526-j9kg00qf 750 11 intact intact JJ cord-022526-j9kg00qf 750 12 intestinal intestinal JJ cord-022526-j9kg00qf 750 13 tissue tissue NN cord-022526-j9kg00qf 750 14 45 45 CD cord-022526-j9kg00qf 750 15 , , , cord-022526-j9kg00qf 750 16 46 46 CD cord-022526-j9kg00qf 750 17 , , , cord-022526-j9kg00qf 750 18 48 48 CD cord-022526-j9kg00qf 750 19 and and CC cord-022526-j9kg00qf 750 20 in in IN cord-022526-j9kg00qf 750 21 isolated isolate VBN cord-022526-j9kg00qf 750 22 colonic colonic JJ cord-022526-j9kg00qf 750 23 T84 T84 NNP cord-022526-j9kg00qf 750 24 cells cell NNS cord-022526-j9kg00qf 750 25 . . . cord-022526-j9kg00qf 751 1 47 47 CD cord-022526-j9kg00qf 751 2 , , , cord-022526-j9kg00qf 751 3 49 49 CD cord-022526-j9kg00qf 751 4 Interactions interaction NNS cord-022526-j9kg00qf 751 5 between between IN cord-022526-j9kg00qf 751 6 ROMs rom NNS cord-022526-j9kg00qf 751 7 and and CC cord-022526-j9kg00qf 751 8 mesenchymal mesenchymal JJ cord-022526-j9kg00qf 751 9 release release NN cord-022526-j9kg00qf 751 10 of of IN cord-022526-j9kg00qf 751 11 PGE PGE NNP cord-022526-j9kg00qf 751 12 2 2 CD cord-022526-j9kg00qf 751 13 /PGI /PGI . cord-022526-j9kg00qf 752 1 2 2 LS cord-022526-j9kg00qf 752 2 may may MD cord-022526-j9kg00qf 752 3 be be VB cord-022526-j9kg00qf 752 4 relevant relevant JJ cord-022526-j9kg00qf 752 5 to to IN cord-022526-j9kg00qf 752 6 the the DT cord-022526-j9kg00qf 752 7 mechanisms mechanism NNS cord-022526-j9kg00qf 752 8 producing produce VBG cord-022526-j9kg00qf 752 9 the the DT cord-022526-j9kg00qf 752 10 diarrheic diarrheic NNS cord-022526-j9kg00qf 752 11 condition condition NN cord-022526-j9kg00qf 752 12 . . . cord-022526-j9kg00qf 753 1 Fibroblasts fibroblast NNS cord-022526-j9kg00qf 753 2 co co VBD cord-022526-j9kg00qf 753 3 - - JJ cord-022526-j9kg00qf 753 4 cultured cultured JJ cord-022526-j9kg00qf 754 1 or or CC cord-022526-j9kg00qf 754 2 juxtaposed juxtapose VBN cord-022526-j9kg00qf 754 3 to to IN cord-022526-j9kg00qf 754 4 colonic colonic JJ cord-022526-j9kg00qf 754 5 T84 T84 NNP cord-022526-j9kg00qf 754 6 cells cell NNS cord-022526-j9kg00qf 754 7 greatly greatly RB cord-022526-j9kg00qf 754 8 increased increase VBD cord-022526-j9kg00qf 754 9 the the DT cord-022526-j9kg00qf 754 10 Clsecretory Clsecretory NNP cord-022526-j9kg00qf 754 11 response response NN cord-022526-j9kg00qf 754 12 to to IN cord-022526-j9kg00qf 754 13 H h NN cord-022526-j9kg00qf 754 14 2 2 CD cord-022526-j9kg00qf 754 15 O o NN cord-022526-j9kg00qf 754 16 2 2 CD cord-022526-j9kg00qf 754 17 in in IN cord-022526-j9kg00qf 754 18 vitro vitro FW cord-022526-j9kg00qf 754 19 through through IN cord-022526-j9kg00qf 754 20 the the DT cord-022526-j9kg00qf 754 21 release release NN cord-022526-j9kg00qf 754 22 of of IN cord-022526-j9kg00qf 754 23 PGE PGE NNP cord-022526-j9kg00qf 754 24 2 2 CD cord-022526-j9kg00qf 754 25 . . . cord-022526-j9kg00qf 754 26 49 49 CD cord-022526-j9kg00qf 755 1 In in IN cord-022526-j9kg00qf 755 2 addition addition NN cord-022526-j9kg00qf 755 3 , , , cord-022526-j9kg00qf 755 4 equine equine JJ cord-022526-j9kg00qf 755 5 colonic colonic JJ cord-022526-j9kg00qf 755 6 mucosa mucosa NN cord-022526-j9kg00qf 755 7 has have VBZ cord-022526-j9kg00qf 755 8 an an DT cord-022526-j9kg00qf 755 9 increased increase VBN cord-022526-j9kg00qf 755 10 sensitivity sensitivity NN cord-022526-j9kg00qf 755 11 to to IN cord-022526-j9kg00qf 755 12 endogenously endogenously RB cord-022526-j9kg00qf 755 13 released release VBN cord-022526-j9kg00qf 755 14 prostaglandin prostaglandin NN cord-022526-j9kg00qf 755 15 by by IN cord-022526-j9kg00qf 755 16 exhibiting exhibit VBG cord-022526-j9kg00qf 755 17 a a DT cord-022526-j9kg00qf 755 18 significant significant JJ cord-022526-j9kg00qf 755 19 secretory secretory JJ cord-022526-j9kg00qf 755 20 response response NN cord-022526-j9kg00qf 755 21 under under IN cord-022526-j9kg00qf 755 22 in in IN cord-022526-j9kg00qf 755 23 vitro vitro FW cord-022526-j9kg00qf 755 24 conditions condition NNS cord-022526-j9kg00qf 755 25 . . . cord-022526-j9kg00qf 756 1 83 83 CD cord-022526-j9kg00qf 756 2 Endotoxin endotoxin NN cord-022526-j9kg00qf 756 3 , , , cord-022526-j9kg00qf 756 4 the the DT cord-022526-j9kg00qf 756 5 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 756 6 component component NN cord-022526-j9kg00qf 756 7 of of IN cord-022526-j9kg00qf 756 8 the the DT cord-022526-j9kg00qf 756 9 outer outer JJ cord-022526-j9kg00qf 756 10 cell cell NN cord-022526-j9kg00qf 756 11 wall wall NN cord-022526-j9kg00qf 756 12 of of IN cord-022526-j9kg00qf 756 13 gram gram NN cord-022526-j9kg00qf 756 14 - - HYPH cord-022526-j9kg00qf 756 15 negative negative JJ cord-022526-j9kg00qf 756 16 bacteria bacteria NNS cord-022526-j9kg00qf 756 17 , , , cord-022526-j9kg00qf 756 18 is be VBZ cord-022526-j9kg00qf 756 19 present present JJ cord-022526-j9kg00qf 756 20 in in IN cord-022526-j9kg00qf 756 21 large large JJ cord-022526-j9kg00qf 756 22 quantities quantity NNS cord-022526-j9kg00qf 756 23 in in IN cord-022526-j9kg00qf 756 24 the the DT cord-022526-j9kg00qf 756 25 large large JJ cord-022526-j9kg00qf 756 26 intestine intestine NN cord-022526-j9kg00qf 756 27 of of IN cord-022526-j9kg00qf 756 28 healthy healthy JJ cord-022526-j9kg00qf 756 29 horses horse NNS cord-022526-j9kg00qf 756 30 . . . cord-022526-j9kg00qf 757 1 81 81 CD cord-022526-j9kg00qf 757 2 , , , cord-022526-j9kg00qf 757 3 83 83 CD cord-022526-j9kg00qf 757 4 Endotoxins endotoxin NNS cord-022526-j9kg00qf 757 5 are be VBP cord-022526-j9kg00qf 757 6 released release VBN cord-022526-j9kg00qf 757 7 into into IN cord-022526-j9kg00qf 757 8 the the DT cord-022526-j9kg00qf 757 9 immediate immediate JJ cord-022526-j9kg00qf 757 10 surroundings surrounding NNS cord-022526-j9kg00qf 757 11 when when WRB cord-022526-j9kg00qf 757 12 gram gram NN cord-022526-j9kg00qf 757 13 - - HYPH cord-022526-j9kg00qf 757 14 negative negative JJ cord-022526-j9kg00qf 757 15 bacteria bacteria NNS cord-022526-j9kg00qf 757 16 undergo undergo VBP cord-022526-j9kg00qf 757 17 rapid rapid JJ cord-022526-j9kg00qf 757 18 proliferation proliferation NN cord-022526-j9kg00qf 757 19 or or CC cord-022526-j9kg00qf 757 20 die die VB cord-022526-j9kg00qf 757 21 . . . cord-022526-j9kg00qf 758 1 84 84 CD cord-022526-j9kg00qf 758 2 , , , cord-022526-j9kg00qf 758 3 85 85 CD cord-022526-j9kg00qf 759 1 The the DT cord-022526-j9kg00qf 759 2 intact intact JJ cord-022526-j9kg00qf 759 3 bowel bowel NN cord-022526-j9kg00qf 759 4 forms form NNS cord-022526-j9kg00qf 759 5 an an DT cord-022526-j9kg00qf 759 6 effective effective JJ cord-022526-j9kg00qf 759 7 barrier barrier NN cord-022526-j9kg00qf 759 8 to to IN cord-022526-j9kg00qf 759 9 the the DT cord-022526-j9kg00qf 759 10 transport transport NN cord-022526-j9kg00qf 759 11 of of IN cord-022526-j9kg00qf 759 12 significant significant JJ cord-022526-j9kg00qf 759 13 amounts amount NNS cord-022526-j9kg00qf 759 14 of of IN cord-022526-j9kg00qf 759 15 these these DT cord-022526-j9kg00qf 759 16 highly highly RB cord-022526-j9kg00qf 759 17 antigenic antigenic JJ cord-022526-j9kg00qf 759 18 toxins toxin NNS cord-022526-j9kg00qf 759 19 , , , cord-022526-j9kg00qf 759 20 but but CC cord-022526-j9kg00qf 759 21 the the DT cord-022526-j9kg00qf 759 22 diseased diseased JJ cord-022526-j9kg00qf 759 23 gut gut NN cord-022526-j9kg00qf 759 24 absorbs absorb VBZ cord-022526-j9kg00qf 759 25 these these DT cord-022526-j9kg00qf 759 26 macromolecules macromolecule NNS cord-022526-j9kg00qf 759 27 in in IN cord-022526-j9kg00qf 759 28 large large JJ cord-022526-j9kg00qf 759 29 amounts amount NNS cord-022526-j9kg00qf 759 30 , , , cord-022526-j9kg00qf 759 31 causing cause VBG cord-022526-j9kg00qf 759 32 the the DT cord-022526-j9kg00qf 759 33 subsequent subsequent JJ cord-022526-j9kg00qf 759 34 adverse adverse JJ cord-022526-j9kg00qf 759 35 systemic systemic JJ cord-022526-j9kg00qf 759 36 effects effect NNS cord-022526-j9kg00qf 759 37 that that WDT cord-022526-j9kg00qf 759 38 are be VBP cord-022526-j9kg00qf 759 39 often often RB cord-022526-j9kg00qf 759 40 life life NN cord-022526-j9kg00qf 759 41 threatening threaten VBG cord-022526-j9kg00qf 759 42 . . . cord-022526-j9kg00qf 760 1 86 86 CD cord-022526-j9kg00qf 760 2 Disruption disruption NN cord-022526-j9kg00qf 760 3 of of IN cord-022526-j9kg00qf 760 4 the the DT cord-022526-j9kg00qf 760 5 intestinal intestinal JJ cord-022526-j9kg00qf 760 6 barrier barrier NN cord-022526-j9kg00qf 760 7 ( ( -LRB- cord-022526-j9kg00qf 760 8 i.e. i.e. FW cord-022526-j9kg00qf 760 9 , , , cord-022526-j9kg00qf 760 10 ischemia ischemia NN cord-022526-j9kg00qf 760 11 , , , cord-022526-j9kg00qf 760 12 trauma trauma NN cord-022526-j9kg00qf 760 13 , , , cord-022526-j9kg00qf 760 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 760 15 conditions condition NNS cord-022526-j9kg00qf 760 16 ) ) -RRB- cord-022526-j9kg00qf 760 17 overwhelms overwhelm VBZ cord-022526-j9kg00qf 760 18 the the DT cord-022526-j9kg00qf 760 19 capacity capacity NN cord-022526-j9kg00qf 760 20 of of IN cord-022526-j9kg00qf 760 21 the the DT cord-022526-j9kg00qf 760 22 liver liver NN cord-022526-j9kg00qf 760 23 to to IN cord-022526-j9kg00qf 760 24 clear clear JJ cord-022526-j9kg00qf 760 25 endotoxins endotoxin NNS cord-022526-j9kg00qf 760 26 , , , cord-022526-j9kg00qf 760 27 and and CC cord-022526-j9kg00qf 760 28 systemic systemic JJ cord-022526-j9kg00qf 760 29 endotoxemia endotoxemia NN cord-022526-j9kg00qf 760 30 ensues ensue VBZ cord-022526-j9kg00qf 760 31 . . . cord-022526-j9kg00qf 761 1 Endotoxins endotoxin NNS cord-022526-j9kg00qf 761 2 have have VBP cord-022526-j9kg00qf 761 3 been be VBN cord-022526-j9kg00qf 761 4 shown show VBN cord-022526-j9kg00qf 761 5 to to TO cord-022526-j9kg00qf 761 6 be be VB cord-022526-j9kg00qf 761 7 potent potent JJ cord-022526-j9kg00qf 761 8 activators activator NNS cord-022526-j9kg00qf 761 9 of of IN cord-022526-j9kg00qf 761 10 the the DT cord-022526-j9kg00qf 761 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 761 12 process process NN cord-022526-j9kg00qf 761 13 , , , cord-022526-j9kg00qf 761 14 stimulating stimulate VBG cord-022526-j9kg00qf 761 15 the the DT cord-022526-j9kg00qf 761 16 production production NN cord-022526-j9kg00qf 761 17 and and CC cord-022526-j9kg00qf 761 18 release release NN cord-022526-j9kg00qf 761 19 of of IN cord-022526-j9kg00qf 761 20 numerous numerous JJ cord-022526-j9kg00qf 761 21 cytokines cytokine NNS cord-022526-j9kg00qf 761 22 by by IN cord-022526-j9kg00qf 761 23 activated activate VBN cord-022526-j9kg00qf 761 24 macrophages macrophage NNS cord-022526-j9kg00qf 761 25 and and CC cord-022526-j9kg00qf 761 26 other other JJ cord-022526-j9kg00qf 761 27 immunocytes immunocyte NNS cord-022526-j9kg00qf 761 28 . . . cord-022526-j9kg00qf 762 1 87 87 CD cord-022526-j9kg00qf 763 1 In in IN cord-022526-j9kg00qf 763 2 vitro vitro FW cord-022526-j9kg00qf 763 3 studies study NNS cord-022526-j9kg00qf 763 4 suggest suggest VBP cord-022526-j9kg00qf 763 5 that that IN cord-022526-j9kg00qf 763 6 endotoxin endotoxin NN cord-022526-j9kg00qf 763 7 activates activate VBZ cord-022526-j9kg00qf 763 8 phagocytic phagocytic JJ cord-022526-j9kg00qf 763 9 granulocytes granulocyte NNS cord-022526-j9kg00qf 763 10 to to TO cord-022526-j9kg00qf 763 11 secrete secrete VB cord-022526-j9kg00qf 763 12 ROMs rom NNS cord-022526-j9kg00qf 763 13 , , , cord-022526-j9kg00qf 763 14 increase increase NN cord-022526-j9kg00qf 763 15 release release NN cord-022526-j9kg00qf 763 16 of of IN cord-022526-j9kg00qf 763 17 lysozymes lysozyme NNS cord-022526-j9kg00qf 763 18 , , , cord-022526-j9kg00qf 763 19 and and CC cord-022526-j9kg00qf 763 20 enhance enhance VB cord-022526-j9kg00qf 763 21 the the DT cord-022526-j9kg00qf 763 22 migratory migratory JJ cord-022526-j9kg00qf 763 23 response response NN cord-022526-j9kg00qf 763 24 to to IN cord-022526-j9kg00qf 763 25 chemotactic chemotactic JJ cord-022526-j9kg00qf 763 26 stimuli stimulus NNS cord-022526-j9kg00qf 763 27 . . . cord-022526-j9kg00qf 764 1 88 88 CD cord-022526-j9kg00qf 764 2 Prostacyclin Prostacyclin NNP cord-022526-j9kg00qf 764 3 and and CC cord-022526-j9kg00qf 764 4 thromboxane thromboxane NN cord-022526-j9kg00qf 764 5 A a DT cord-022526-j9kg00qf 764 6 2 2 CD cord-022526-j9kg00qf 764 7 mediate mediate VBP cord-022526-j9kg00qf 764 8 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 764 9 dysfunction dysfunction NN cord-022526-j9kg00qf 764 10 , , , cord-022526-j9kg00qf 764 11 and and CC cord-022526-j9kg00qf 764 12 lipoxygenase lipoxygenase NN cord-022526-j9kg00qf 764 13 products product NNS cord-022526-j9kg00qf 764 14 may may MD cord-022526-j9kg00qf 764 15 induce induce VB cord-022526-j9kg00qf 764 16 tissue tissue NN cord-022526-j9kg00qf 764 17 ischemia ischemia NN cord-022526-j9kg00qf 764 18 . . . cord-022526-j9kg00qf 765 1 89 89 CD cord-022526-j9kg00qf 766 1 The the DT cord-022526-j9kg00qf 766 2 cytokine cytokine NN cord-022526-j9kg00qf 766 3 interleukin-1 interleukin-1 NN cord-022526-j9kg00qf 766 4 causes cause VBZ cord-022526-j9kg00qf 766 5 a a DT cord-022526-j9kg00qf 766 6 febrile febrile JJ cord-022526-j9kg00qf 766 7 response response NN cord-022526-j9kg00qf 766 8 and and CC cord-022526-j9kg00qf 766 9 initiates initiate VBZ cord-022526-j9kg00qf 766 10 the the DT cord-022526-j9kg00qf 766 11 acute acute JJ cord-022526-j9kg00qf 766 12 phase phase NN cord-022526-j9kg00qf 766 13 response response NN cord-022526-j9kg00qf 766 14 . . . cord-022526-j9kg00qf 767 1 90 90 CD cord-022526-j9kg00qf 767 2 Tumor tumor NN cord-022526-j9kg00qf 767 3 necrosis necrosis NN cord-022526-j9kg00qf 767 4 factor factor NN cord-022526-j9kg00qf 767 5 contributes contribute VBZ cord-022526-j9kg00qf 767 6 to to IN cord-022526-j9kg00qf 767 7 many many JJ cord-022526-j9kg00qf 767 8 of of IN cord-022526-j9kg00qf 767 9 the the DT cord-022526-j9kg00qf 767 10 abnormal abnormal JJ cord-022526-j9kg00qf 767 11 physiologic physiologic JJ cord-022526-j9kg00qf 767 12 responses response NNS cord-022526-j9kg00qf 767 13 , , , cord-022526-j9kg00qf 767 14 particularly particularly RB cord-022526-j9kg00qf 767 15 hemostatic hemostatic JJ cord-022526-j9kg00qf 767 16 functions function NNS cord-022526-j9kg00qf 767 17 that that WDT cord-022526-j9kg00qf 767 18 potentiate potentiate VBP cord-022526-j9kg00qf 767 19 coagulopathy coagulopathy NN cord-022526-j9kg00qf 767 20 . . . cord-022526-j9kg00qf 768 1 91 91 CD cord-022526-j9kg00qf 768 2 Additional additional JJ cord-022526-j9kg00qf 768 3 mediators mediator NNS cord-022526-j9kg00qf 768 4 include include VBP cord-022526-j9kg00qf 768 5 interleukin-6 interleukin-6 NNP cord-022526-j9kg00qf 768 6 , , , cord-022526-j9kg00qf 768 7 platelet platelet NN cord-022526-j9kg00qf 768 8 - - HYPH cord-022526-j9kg00qf 768 9 activating activate VBG cord-022526-j9kg00qf 768 10 factor factor NN cord-022526-j9kg00qf 768 11 , , , cord-022526-j9kg00qf 768 12 procoagulant procoagulant NN cord-022526-j9kg00qf 768 13 mediators mediator NNS cord-022526-j9kg00qf 768 14 , , , cord-022526-j9kg00qf 768 15 and and CC cord-022526-j9kg00qf 768 16 various various JJ cord-022526-j9kg00qf 768 17 other other JJ cord-022526-j9kg00qf 768 18 speculated speculate VBN cord-022526-j9kg00qf 768 19 substances substance NNS cord-022526-j9kg00qf 768 20 . . . cord-022526-j9kg00qf 769 1 84 84 CD cord-022526-j9kg00qf 769 2 Endotoxins endotoxin NNS cord-022526-j9kg00qf 769 3 trigger trigger VBP cord-022526-j9kg00qf 769 4 mucosal mucosal JJ cord-022526-j9kg00qf 769 5 immune immune JJ cord-022526-j9kg00qf 769 6 cells cell NNS cord-022526-j9kg00qf 769 7 and and CC cord-022526-j9kg00qf 769 8 subsequent subsequent JJ cord-022526-j9kg00qf 769 9 release release NN cord-022526-j9kg00qf 769 10 of of IN cord-022526-j9kg00qf 769 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 769 12 mediators mediator NNS cord-022526-j9kg00qf 769 13 in in IN cord-022526-j9kg00qf 769 14 cases case NNS cord-022526-j9kg00qf 769 15 of of IN cord-022526-j9kg00qf 769 16 colitis colitis NN cord-022526-j9kg00qf 769 17 . . . cord-022526-j9kg00qf 770 1 The the DT cord-022526-j9kg00qf 770 2 first first JJ cord-022526-j9kg00qf 770 3 report report NN cord-022526-j9kg00qf 770 4 of of IN cord-022526-j9kg00qf 770 5 experimentally experimentally RB cord-022526-j9kg00qf 770 6 induced induce VBN cord-022526-j9kg00qf 770 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 770 8 described describe VBD cord-022526-j9kg00qf 770 9 clinical clinical JJ cord-022526-j9kg00qf 770 10 signs sign NNS cord-022526-j9kg00qf 770 11 and and CC cord-022526-j9kg00qf 770 12 hematologic hematologic JJ cord-022526-j9kg00qf 770 13 findings finding NNS cord-022526-j9kg00qf 770 14 that that WDT cord-022526-j9kg00qf 770 15 closely closely RB cord-022526-j9kg00qf 770 16 paralleled parallel VBD cord-022526-j9kg00qf 770 17 those those DT cord-022526-j9kg00qf 770 18 reported report VBN cord-022526-j9kg00qf 770 19 for for IN cord-022526-j9kg00qf 770 20 severe severe JJ cord-022526-j9kg00qf 770 21 colitis colitis NN cord-022526-j9kg00qf 770 22 in in IN cord-022526-j9kg00qf 770 23 horses horse NNS cord-022526-j9kg00qf 770 24 . . . cord-022526-j9kg00qf 771 1 92 92 CD cord-022526-j9kg00qf 771 2 Studies study NNS cord-022526-j9kg00qf 771 3 in in IN cord-022526-j9kg00qf 771 4 which which WDT cord-022526-j9kg00qf 771 5 endotoxin endotoxin NN cord-022526-j9kg00qf 771 6 was be VBD cord-022526-j9kg00qf 771 7 administered administer VBN cord-022526-j9kg00qf 771 8 intravenously intravenously RB cord-022526-j9kg00qf 771 9 in in IN cord-022526-j9kg00qf 771 10 human human JJ cord-022526-j9kg00qf 771 11 beings being NNS cord-022526-j9kg00qf 771 12 and and CC cord-022526-j9kg00qf 771 13 laboratory laboratory NN cord-022526-j9kg00qf 771 14 animals animal NNS cord-022526-j9kg00qf 771 15 caused cause VBD cord-022526-j9kg00qf 771 16 significant significant JJ cord-022526-j9kg00qf 771 17 dose dose NN cord-022526-j9kg00qf 771 18 - - HYPH cord-022526-j9kg00qf 771 19 related relate VBN cord-022526-j9kg00qf 771 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 771 21 changes change NNS cord-022526-j9kg00qf 771 22 , , , cord-022526-j9kg00qf 771 23 ranging range VBG cord-022526-j9kg00qf 771 24 from from IN cord-022526-j9kg00qf 771 25 mild mild JJ cord-022526-j9kg00qf 771 26 diarrhea diarrhea NN cord-022526-j9kg00qf 771 27 to to IN cord-022526-j9kg00qf 771 28 bloody bloody JJ cord-022526-j9kg00qf 771 29 , , , cord-022526-j9kg00qf 771 30 watery watery JJ cord-022526-j9kg00qf 771 31 diarrhea diarrhea NN cord-022526-j9kg00qf 771 32 . . . cord-022526-j9kg00qf 772 1 93 93 CD cord-022526-j9kg00qf 773 1 , , , cord-022526-j9kg00qf 773 2 94 94 CD cord-022526-j9kg00qf 774 1 In in IN cord-022526-j9kg00qf 774 2 vitro vitro FW cord-022526-j9kg00qf 774 3 studies study NNS cord-022526-j9kg00qf 774 4 on on IN cord-022526-j9kg00qf 774 5 the the DT cord-022526-j9kg00qf 774 6 effects effect NNS cord-022526-j9kg00qf 774 7 of of IN cord-022526-j9kg00qf 774 8 endotoxin endotoxin NN cord-022526-j9kg00qf 774 9 on on IN cord-022526-j9kg00qf 774 10 intestinal intestinal JJ cord-022526-j9kg00qf 774 11 water water NN cord-022526-j9kg00qf 774 12 and and CC cord-022526-j9kg00qf 774 13 electrolyte electrolyte JJ cord-022526-j9kg00qf 774 14 transport transport NN cord-022526-j9kg00qf 774 15 in in IN cord-022526-j9kg00qf 774 16 adult adult NN cord-022526-j9kg00qf 774 17 male male JJ cord-022526-j9kg00qf 774 18 rats rat NNS cord-022526-j9kg00qf 774 19 showed show VBD cord-022526-j9kg00qf 774 20 a a DT cord-022526-j9kg00qf 774 21 significant significant JJ cord-022526-j9kg00qf 774 22 decrease decrease NN cord-022526-j9kg00qf 774 23 in in IN cord-022526-j9kg00qf 774 24 net net JJ cord-022526-j9kg00qf 774 25 colonic colonic JJ cord-022526-j9kg00qf 774 26 sodium sodium NN cord-022526-j9kg00qf 774 27 absorption absorption NN cord-022526-j9kg00qf 774 28 and and CC cord-022526-j9kg00qf 774 29 increased increase VBN cord-022526-j9kg00qf 774 30 colonic colonic JJ cord-022526-j9kg00qf 774 31 permeability permeability NN cord-022526-j9kg00qf 774 32 . . . cord-022526-j9kg00qf 775 1 55 55 CD cord-022526-j9kg00qf 776 1 In in IN cord-022526-j9kg00qf 776 2 animal animal NN cord-022526-j9kg00qf 776 3 models model NNS cord-022526-j9kg00qf 776 4 of of IN cord-022526-j9kg00qf 776 5 protein protein NN cord-022526-j9kg00qf 776 6 energy energy NN cord-022526-j9kg00qf 776 7 deficiency deficiency NN cord-022526-j9kg00qf 776 8 , , , cord-022526-j9kg00qf 776 9 endotoxin endotoxin NN cord-022526-j9kg00qf 776 10 - - HYPH cord-022526-j9kg00qf 776 11 induced induce VBN cord-022526-j9kg00qf 776 12 mortality mortality NN cord-022526-j9kg00qf 776 13 increased increase VBD cord-022526-j9kg00qf 776 14 compared compare VBN cord-022526-j9kg00qf 776 15 with with IN cord-022526-j9kg00qf 776 16 that that DT cord-022526-j9kg00qf 776 17 of of IN cord-022526-j9kg00qf 776 18 well well RB cord-022526-j9kg00qf 776 19 - - HYPH cord-022526-j9kg00qf 776 20 nourished nourish VBN cord-022526-j9kg00qf 776 21 control control NN cord-022526-j9kg00qf 776 22 animals animal NNS cord-022526-j9kg00qf 776 23 . . . cord-022526-j9kg00qf 777 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 777 2 depresses depress VBZ cord-022526-j9kg00qf 777 3 lymphocyte lymphocyte NN cord-022526-j9kg00qf 777 4 responses response NNS cord-022526-j9kg00qf 777 5 to to IN cord-022526-j9kg00qf 777 6 specific specific JJ cord-022526-j9kg00qf 777 7 mitogens mitogen NNS cord-022526-j9kg00qf 777 8 . . . cord-022526-j9kg00qf 778 1 95 95 CD cord-022526-j9kg00qf 779 1 Thus thus RB cord-022526-j9kg00qf 779 2 the the DT cord-022526-j9kg00qf 779 3 adverse adverse JJ cord-022526-j9kg00qf 779 4 effects effect NNS cord-022526-j9kg00qf 779 5 of of IN cord-022526-j9kg00qf 779 6 malnutrition malnutrition NN cord-022526-j9kg00qf 779 7 and and CC cord-022526-j9kg00qf 779 8 endotoxin endotoxin NN cord-022526-j9kg00qf 779 9 are be VBP cord-022526-j9kg00qf 779 10 mutually mutually RB cord-022526-j9kg00qf 779 11 aggravating aggravating JJ cord-022526-j9kg00qf 779 12 . . . cord-022526-j9kg00qf 780 1 The the DT cord-022526-j9kg00qf 780 2 importance importance NN cord-022526-j9kg00qf 780 3 of of IN cord-022526-j9kg00qf 780 4 a a DT cord-022526-j9kg00qf 780 5 normal normal JJ cord-022526-j9kg00qf 780 6 immune immune JJ cord-022526-j9kg00qf 780 7 system system NN cord-022526-j9kg00qf 780 8 to to IN cord-022526-j9kg00qf 780 9 the the DT cord-022526-j9kg00qf 780 10 defense defense NN cord-022526-j9kg00qf 780 11 of of IN cord-022526-j9kg00qf 780 12 the the DT cord-022526-j9kg00qf 780 13 mucosal mucosal JJ cord-022526-j9kg00qf 780 14 surface surface NN cord-022526-j9kg00qf 780 15 of of IN cord-022526-j9kg00qf 780 16 the the DT cord-022526-j9kg00qf 780 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 780 18 tract tract NN cord-022526-j9kg00qf 780 19 is be VBZ cord-022526-j9kg00qf 780 20 evident evident JJ cord-022526-j9kg00qf 780 21 in in IN cord-022526-j9kg00qf 780 22 the the DT cord-022526-j9kg00qf 780 23 immunosuppressed immunosuppressed JJ cord-022526-j9kg00qf 780 24 state state NN cord-022526-j9kg00qf 780 25 . . . cord-022526-j9kg00qf 781 1 Primary primary JJ cord-022526-j9kg00qf 781 2 immunodeficiencies immunodeficiency NNS cord-022526-j9kg00qf 781 3 affecting affect VBG cord-022526-j9kg00qf 781 4 the the DT cord-022526-j9kg00qf 781 5 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 781 6 tract tract NN cord-022526-j9kg00qf 781 7 are be VBP cord-022526-j9kg00qf 781 8 well well RB cord-022526-j9kg00qf 781 9 documented document VBN cord-022526-j9kg00qf 781 10 . . . cord-022526-j9kg00qf 782 1 [ [ -LRB- cord-022526-j9kg00qf 782 2 96 96 CD cord-022526-j9kg00qf 782 3 ] ] -RRB- cord-022526-j9kg00qf 782 4 [ [ -LRB- cord-022526-j9kg00qf 782 5 97 97 CD cord-022526-j9kg00qf 782 6 ] ] -RRB- cord-022526-j9kg00qf 782 7 [ [ -LRB- cord-022526-j9kg00qf 782 8 98 98 CD cord-022526-j9kg00qf 782 9 ] ] -RRB- cord-022526-j9kg00qf 783 1 Common common JJ cord-022526-j9kg00qf 783 2 agammaglobulinemia agammaglobulinemia NN cord-022526-j9kg00qf 783 3 is be VBZ cord-022526-j9kg00qf 783 4 the the DT cord-022526-j9kg00qf 783 5 most most RBS cord-022526-j9kg00qf 783 6 frequently frequently RB cord-022526-j9kg00qf 783 7 reported report VBN cord-022526-j9kg00qf 783 8 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 783 9 disease disease NN cord-022526-j9kg00qf 783 10 and and CC cord-022526-j9kg00qf 783 11 causes cause VBZ cord-022526-j9kg00qf 783 12 B b NN cord-022526-j9kg00qf 783 13 cell cell NN cord-022526-j9kg00qf 783 14 deficiency deficiency NN cord-022526-j9kg00qf 783 15 - - HYPH cord-022526-j9kg00qf 783 16 associated associate VBN cord-022526-j9kg00qf 783 17 giardiasis giardiasis NN cord-022526-j9kg00qf 783 18 . . . cord-022526-j9kg00qf 784 1 99 99 CD cord-022526-j9kg00qf 785 1 Interestingly interestingly RB cord-022526-j9kg00qf 785 2 , , , cord-022526-j9kg00qf 785 3 selective selective JJ cord-022526-j9kg00qf 785 4 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 785 5 A a NN cord-022526-j9kg00qf 785 6 ( ( -LRB- cord-022526-j9kg00qf 785 7 IgA IgA NNP cord-022526-j9kg00qf 785 8 ) ) -RRB- cord-022526-j9kg00qf 785 9 deficiency deficiency NN cord-022526-j9kg00qf 785 10 rarely rarely RB cord-022526-j9kg00qf 785 11 results result VBZ cord-022526-j9kg00qf 785 12 in in IN cord-022526-j9kg00qf 785 13 intestinal intestinal JJ cord-022526-j9kg00qf 785 14 disease disease NN cord-022526-j9kg00qf 785 15 because because IN cord-022526-j9kg00qf 785 16 of of IN cord-022526-j9kg00qf 785 17 a a DT cord-022526-j9kg00qf 785 18 speculated speculate VBN cord-022526-j9kg00qf 785 19 increase increase NN cord-022526-j9kg00qf 785 20 in in IN cord-022526-j9kg00qf 785 21 mucosal mucosal JJ cord-022526-j9kg00qf 785 22 IgM IgM NNP cord-022526-j9kg00qf 785 23 response response NN cord-022526-j9kg00qf 785 24 . . . cord-022526-j9kg00qf 786 1 However however RB cord-022526-j9kg00qf 786 2 , , , cord-022526-j9kg00qf 786 3 combined combine VBN cord-022526-j9kg00qf 786 4 IgA IgA NNP cord-022526-j9kg00qf 786 5 and and CC cord-022526-j9kg00qf 786 6 IgM IgM NNP cord-022526-j9kg00qf 786 7 deficiencies deficiency NNS cord-022526-j9kg00qf 786 8 with with IN cord-022526-j9kg00qf 786 9 a a DT cord-022526-j9kg00qf 786 10 higher high JJR cord-022526-j9kg00qf 786 11 incidence incidence NN cord-022526-j9kg00qf 786 12 of of IN cord-022526-j9kg00qf 786 13 intestinal intestinal JJ cord-022526-j9kg00qf 786 14 disease disease NN cord-022526-j9kg00qf 786 15 occur occur VBP cord-022526-j9kg00qf 786 16 . . . cord-022526-j9kg00qf 787 1 A a DT cord-022526-j9kg00qf 787 2 selective selective JJ cord-022526-j9kg00qf 787 3 deficiency deficiency NN cord-022526-j9kg00qf 787 4 of of IN cord-022526-j9kg00qf 787 5 secretory secretory JJ cord-022526-j9kg00qf 787 6 IgA IgA NNP cord-022526-j9kg00qf 787 7 has have VBZ cord-022526-j9kg00qf 787 8 been be VBN cord-022526-j9kg00qf 787 9 associated associate VBN cord-022526-j9kg00qf 787 10 with with IN cord-022526-j9kg00qf 787 11 intestinal intestinal JJ cord-022526-j9kg00qf 787 12 candidiasis candidiasi NNS cord-022526-j9kg00qf 787 13 . . . cord-022526-j9kg00qf 788 1 Certain certain JJ cord-022526-j9kg00qf 788 2 mucosal mucosal JJ cord-022526-j9kg00qf 788 3 pathogens pathogen NNS cord-022526-j9kg00qf 788 4 may may MD cord-022526-j9kg00qf 788 5 enhance enhance VB cord-022526-j9kg00qf 788 6 their -PRON- PRP$ cord-022526-j9kg00qf 788 7 pathogenicity pathogenicity NN cord-022526-j9kg00qf 788 8 by by IN cord-022526-j9kg00qf 788 9 producing produce VBG cord-022526-j9kg00qf 788 10 IgA IgA NNP cord-022526-j9kg00qf 788 11 proteases protease NNS cord-022526-j9kg00qf 788 12 . . . cord-022526-j9kg00qf 789 1 99 99 CD cord-022526-j9kg00qf 789 2 Defects defect NNS cord-022526-j9kg00qf 789 3 in in IN cord-022526-j9kg00qf 789 4 cell cell NN cord-022526-j9kg00qf 789 5 - - HYPH cord-022526-j9kg00qf 789 6 mediated mediate VBN cord-022526-j9kg00qf 789 7 immunity immunity NN cord-022526-j9kg00qf 789 8 are be VBP cord-022526-j9kg00qf 789 9 associated associate VBN cord-022526-j9kg00qf 789 10 most most RBS cord-022526-j9kg00qf 789 11 commonly commonly RB cord-022526-j9kg00qf 789 12 with with IN cord-022526-j9kg00qf 789 13 intractable intractable JJ cord-022526-j9kg00qf 789 14 diarrhea diarrhea NN cord-022526-j9kg00qf 789 15 , , , cord-022526-j9kg00qf 789 16 and and CC cord-022526-j9kg00qf 789 17 organisms organism NNS cord-022526-j9kg00qf 789 18 frequently frequently RB cord-022526-j9kg00qf 789 19 involved involve VBN cord-022526-j9kg00qf 789 20 include include VBP cord-022526-j9kg00qf 789 21 Salmonella Salmonella NNP cord-022526-j9kg00qf 789 22 spp spp NNS cord-022526-j9kg00qf 789 23 . . . cord-022526-j9kg00qf 790 1 , , , cord-022526-j9kg00qf 790 2 Escherichia Escherichia NNP cord-022526-j9kg00qf 790 3 coli coli NNS cord-022526-j9kg00qf 790 4 , , , cord-022526-j9kg00qf 790 5 and and CC cord-022526-j9kg00qf 790 6 Shigella Shigella NNP cord-022526-j9kg00qf 790 7 spp spp NNS cord-022526-j9kg00qf 790 8 . . . cord-022526-j9kg00qf 791 1 100 100 CD cord-022526-j9kg00qf 791 2 Acquired acquire VBN cord-022526-j9kg00qf 791 3 immunodeficiency immunodeficiency NN cord-022526-j9kg00qf 791 4 or or CC cord-022526-j9kg00qf 791 5 immunosuppression immunosuppression NN cord-022526-j9kg00qf 791 6 in in IN cord-022526-j9kg00qf 791 7 adults adult NNS cord-022526-j9kg00qf 791 8 can can MD cord-022526-j9kg00qf 791 9 result result VB cord-022526-j9kg00qf 791 10 from from IN cord-022526-j9kg00qf 791 11 infectious infectious JJ cord-022526-j9kg00qf 791 12 diseases disease NNS cord-022526-j9kg00qf 791 13 ( ( -LRB- cord-022526-j9kg00qf 791 14 particularly particularly RB cord-022526-j9kg00qf 791 15 viral viral JJ cord-022526-j9kg00qf 791 16 ) ) -RRB- cord-022526-j9kg00qf 791 17 , , , cord-022526-j9kg00qf 791 18 nutritional nutritional JJ cord-022526-j9kg00qf 791 19 deficiencies deficiency NNS cord-022526-j9kg00qf 791 20 , , , cord-022526-j9kg00qf 791 21 aging age VBG cord-022526-j9kg00qf 791 22 phenomenon phenomenon NN cord-022526-j9kg00qf 791 23 , , , cord-022526-j9kg00qf 791 24 and and CC cord-022526-j9kg00qf 791 25 drugs drug NNS cord-022526-j9kg00qf 791 26 ( ( -LRB- cord-022526-j9kg00qf 791 27 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 791 28 , , , cord-022526-j9kg00qf 791 29 azathioprine azathioprine NN cord-022526-j9kg00qf 791 30 , , , cord-022526-j9kg00qf 791 31 cyclophosphamide cyclophosphamide RB cord-022526-j9kg00qf 791 32 ) ) -RRB- cord-022526-j9kg00qf 791 33 . . . cord-022526-j9kg00qf 792 1 Nutrition nutrition NN cord-022526-j9kg00qf 792 2 is be VBZ cord-022526-j9kg00qf 792 3 a a DT cord-022526-j9kg00qf 792 4 critical critical JJ cord-022526-j9kg00qf 792 5 determinant determinant NN cord-022526-j9kg00qf 792 6 of of IN cord-022526-j9kg00qf 792 7 immunocompetence immunocompetence NN cord-022526-j9kg00qf 792 8 and and CC cord-022526-j9kg00qf 792 9 risk risk NN cord-022526-j9kg00qf 792 10 of of IN cord-022526-j9kg00qf 792 11 illness illness NN cord-022526-j9kg00qf 792 12 . . . cord-022526-j9kg00qf 793 1 101 101 CD cord-022526-j9kg00qf 793 2 , , , cord-022526-j9kg00qf 793 3 102 102 CD cord-022526-j9kg00qf 793 4 Impaired impaired JJ cord-022526-j9kg00qf 793 5 systemic systemic JJ cord-022526-j9kg00qf 793 6 and and CC cord-022526-j9kg00qf 793 7 mucosal mucosal JJ cord-022526-j9kg00qf 793 8 immunity immunity NN cord-022526-j9kg00qf 793 9 contribute contribute VBP cord-022526-j9kg00qf 793 10 to to IN cord-022526-j9kg00qf 793 11 an an DT cord-022526-j9kg00qf 793 12 increased increase VBN cord-022526-j9kg00qf 793 13 frequency frequency NN cord-022526-j9kg00qf 793 14 and and CC cord-022526-j9kg00qf 793 15 severity severity NN cord-022526-j9kg00qf 793 16 of of IN cord-022526-j9kg00qf 793 17 intestinal intestinal JJ cord-022526-j9kg00qf 793 18 infections infection NNS cord-022526-j9kg00qf 793 19 observed observe VBN cord-022526-j9kg00qf 793 20 in in IN cord-022526-j9kg00qf 793 21 cases case NNS cord-022526-j9kg00qf 793 22 of of IN cord-022526-j9kg00qf 793 23 undernourishment undernourishment NN cord-022526-j9kg00qf 793 24 . . . cord-022526-j9kg00qf 794 1 Abnormalities abnormality NNS cord-022526-j9kg00qf 794 2 occur occur VBP cord-022526-j9kg00qf 794 3 in in IN cord-022526-j9kg00qf 794 4 cell cell NN cord-022526-j9kg00qf 794 5 - - HYPH cord-022526-j9kg00qf 794 6 mediated mediate VBN cord-022526-j9kg00qf 794 7 immunity immunity NN cord-022526-j9kg00qf 794 8 , , , cord-022526-j9kg00qf 794 9 complement complement NN cord-022526-j9kg00qf 794 10 system system NN cord-022526-j9kg00qf 794 11 , , , cord-022526-j9kg00qf 794 12 phagocytic phagocytic JJ cord-022526-j9kg00qf 794 13 function function NN cord-022526-j9kg00qf 794 14 , , , cord-022526-j9kg00qf 794 15 mucosal mucosal JJ cord-022526-j9kg00qf 794 16 secretory secretory JJ cord-022526-j9kg00qf 794 17 antibody antibody NN cord-022526-j9kg00qf 794 18 response response NN cord-022526-j9kg00qf 794 19 , , , cord-022526-j9kg00qf 794 20 and and CC cord-022526-j9kg00qf 794 21 antibody antibody NN cord-022526-j9kg00qf 794 22 affinity affinity NN cord-022526-j9kg00qf 794 23 . . . cord-022526-j9kg00qf 795 1 Morbidity morbidity NN cord-022526-j9kg00qf 795 2 caused cause VBN cord-022526-j9kg00qf 795 3 by by IN cord-022526-j9kg00qf 795 4 diarrheal diarrheal JJ cord-022526-j9kg00qf 795 5 disease disease NN cord-022526-j9kg00qf 795 6 is be VBZ cord-022526-j9kg00qf 795 7 increased increase VBN cord-022526-j9kg00qf 795 8 particularly particularly RB cord-022526-j9kg00qf 795 9 among among IN cord-022526-j9kg00qf 795 10 individuals individual NNS cord-022526-j9kg00qf 795 11 with with IN cord-022526-j9kg00qf 795 12 stunted stunted JJ cord-022526-j9kg00qf 795 13 growth growth NN cord-022526-j9kg00qf 795 14 rate rate NN cord-022526-j9kg00qf 795 15 because because IN cord-022526-j9kg00qf 795 16 of of IN cord-022526-j9kg00qf 795 17 malnourishment malnourishment NN cord-022526-j9kg00qf 795 18 . . . cord-022526-j9kg00qf 796 1 102 102 CD cord-022526-j9kg00qf 797 1 The the DT cord-022526-j9kg00qf 797 2 critical critical JJ cord-022526-j9kg00qf 797 3 role role NN cord-022526-j9kg00qf 797 4 of of IN cord-022526-j9kg00qf 797 5 several several JJ cord-022526-j9kg00qf 797 6 vitamins vitamin NNS cord-022526-j9kg00qf 797 7 and and CC cord-022526-j9kg00qf 797 8 minerals mineral NNS cord-022526-j9kg00qf 797 9 in in IN cord-022526-j9kg00qf 797 10 immunocompetence immunocompetence NN cord-022526-j9kg00qf 797 11 has have VBZ cord-022526-j9kg00qf 797 12 been be VBN cord-022526-j9kg00qf 797 13 substantiated substantiate VBN cord-022526-j9kg00qf 797 14 in in IN cord-022526-j9kg00qf 797 15 animals animal NNS cord-022526-j9kg00qf 797 16 deprived deprive VBN cord-022526-j9kg00qf 797 17 of of IN cord-022526-j9kg00qf 797 18 one one CD cord-022526-j9kg00qf 797 19 dietary dietary JJ cord-022526-j9kg00qf 797 20 element element NN cord-022526-j9kg00qf 797 21 and and CC cord-022526-j9kg00qf 797 22 findings finding NNS cord-022526-j9kg00qf 797 23 in in IN cord-022526-j9kg00qf 797 24 human human JJ cord-022526-j9kg00qf 797 25 patients patient NNS cord-022526-j9kg00qf 797 26 with with IN cord-022526-j9kg00qf 797 27 single single JJ cord-022526-j9kg00qf 797 28 - - HYPH cord-022526-j9kg00qf 797 29 nutrient nutrient NN cord-022526-j9kg00qf 797 30 deficiency deficiency NN cord-022526-j9kg00qf 797 31 . . . cord-022526-j9kg00qf 798 1 Tables table NNS cord-022526-j9kg00qf 798 2 13.3 13.3 CD cord-022526-j9kg00qf 798 3 - - SYM cord-022526-j9kg00qf 798 4 3 3 CD cord-022526-j9kg00qf 798 5 _SP cord-022526-j9kg00qf 798 6 and and CC cord-022526-j9kg00qf 798 7 13 13 CD cord-022526-j9kg00qf 798 8 .3 .3 CD cord-022526-j9kg00qf 798 9 - - SYM cord-022526-j9kg00qf 798 10 4 4 CD cord-022526-j9kg00qf 798 11 summarize summarize VB cord-022526-j9kg00qf 798 12 nutritional nutritional JJ cord-022526-j9kg00qf 798 13 - - HYPH cord-022526-j9kg00qf 798 14 related relate VBN cord-022526-j9kg00qf 798 15 immune immune JJ cord-022526-j9kg00qf 798 16 system system NN cord-022526-j9kg00qf 798 17 abnormalities abnormality NNS cord-022526-j9kg00qf 798 18 . . . cord-022526-j9kg00qf 799 1 In in IN cord-022526-j9kg00qf 799 2 summary summary NN cord-022526-j9kg00qf 799 3 , , , cord-022526-j9kg00qf 799 4 nutritional nutritional JJ cord-022526-j9kg00qf 799 5 deficiency deficiency NN cord-022526-j9kg00qf 799 6 can can MD cord-022526-j9kg00qf 799 7 cause cause VB cord-022526-j9kg00qf 799 8 increased increase VBN cord-022526-j9kg00qf 799 9 colonization colonization NN cord-022526-j9kg00qf 799 10 of of IN cord-022526-j9kg00qf 799 11 the the DT cord-022526-j9kg00qf 799 12 intestine intestine NN cord-022526-j9kg00qf 799 13 with with IN cord-022526-j9kg00qf 799 14 microorganisms microorganism NNS cord-022526-j9kg00qf 799 15 , , , cord-022526-j9kg00qf 799 16 alter alter VB cord-022526-j9kg00qf 799 17 the the DT cord-022526-j9kg00qf 799 18 symbiotic symbiotic JJ cord-022526-j9kg00qf 799 19 characteristics characteristic NNS cord-022526-j9kg00qf 799 20 of of IN cord-022526-j9kg00qf 799 21 resident resident JJ cord-022526-j9kg00qf 799 22 intestinal intestinal JJ cord-022526-j9kg00qf 799 23 bacterial bacterial JJ cord-022526-j9kg00qf 799 24 populations population NNS cord-022526-j9kg00qf 799 25 , , , cord-022526-j9kg00qf 799 26 and and CC cord-022526-j9kg00qf 799 27 impair impair VB cord-022526-j9kg00qf 799 28 defenses defense NNS cord-022526-j9kg00qf 799 29 of of IN cord-022526-j9kg00qf 799 30 the the DT cord-022526-j9kg00qf 799 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 799 32 tract tract NN cord-022526-j9kg00qf 799 33 , , , cord-022526-j9kg00qf 799 34 allowing allow VBG cord-022526-j9kg00qf 799 35 increased increase VBN cord-022526-j9kg00qf 799 36 risk risk NN cord-022526-j9kg00qf 799 37 of of IN cord-022526-j9kg00qf 799 38 systemic systemic JJ cord-022526-j9kg00qf 799 39 spread spread NN cord-022526-j9kg00qf 799 40 of of IN cord-022526-j9kg00qf 799 41 infection infection NN cord-022526-j9kg00qf 799 42 and and CC cord-022526-j9kg00qf 799 43 absorption absorption NN cord-022526-j9kg00qf 799 44 of of IN cord-022526-j9kg00qf 799 45 macromolecules macromolecule NNS cord-022526-j9kg00qf 799 46 ( ( -LRB- cord-022526-j9kg00qf 799 47 in in IN cord-022526-j9kg00qf 799 48 particular particular JJ cord-022526-j9kg00qf 799 49 , , , cord-022526-j9kg00qf 799 50 endotoxin endotoxin NN cord-022526-j9kg00qf 799 51 ) ) -RRB- cord-022526-j9kg00qf 799 52 . . . cord-022526-j9kg00qf 800 1 Indigenous indigenous JJ cord-022526-j9kg00qf 800 2 microflora microflora NN cord-022526-j9kg00qf 800 3 greatly greatly RB cord-022526-j9kg00qf 800 4 impede impede VBP cord-022526-j9kg00qf 800 5 colonization colonization NN cord-022526-j9kg00qf 800 6 of of IN cord-022526-j9kg00qf 800 7 the the DT cord-022526-j9kg00qf 800 8 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 800 9 mucosa mucosa NN cord-022526-j9kg00qf 800 10 by by IN cord-022526-j9kg00qf 800 11 pathogenic pathogenic JJ cord-022526-j9kg00qf 800 12 organisms organism NNS cord-022526-j9kg00qf 800 13 . . . cord-022526-j9kg00qf 801 1 The the DT cord-022526-j9kg00qf 801 2 ability ability NN cord-022526-j9kg00qf 801 3 of of IN cord-022526-j9kg00qf 801 4 a a DT cord-022526-j9kg00qf 801 5 potential potential JJ cord-022526-j9kg00qf 801 6 pathogen pathogen NN cord-022526-j9kg00qf 801 7 to to TO cord-022526-j9kg00qf 801 8 initiate initiate VB cord-022526-j9kg00qf 801 9 an an DT cord-022526-j9kg00qf 801 10 infection infection NN cord-022526-j9kg00qf 801 11 depends depend VBZ cord-022526-j9kg00qf 801 12 on on IN cord-022526-j9kg00qf 801 13 its -PRON- PRP$ cord-022526-j9kg00qf 801 14 ability ability NN cord-022526-j9kg00qf 801 15 to to TO cord-022526-j9kg00qf 801 16 breach breach VB cord-022526-j9kg00qf 801 17 the the DT cord-022526-j9kg00qf 801 18 mucosal mucosal JJ cord-022526-j9kg00qf 801 19 epithelial epithelial JJ cord-022526-j9kg00qf 801 20 barrier barrier NN cord-022526-j9kg00qf 801 21 . . . cord-022526-j9kg00qf 802 1 One one CD cord-022526-j9kg00qf 802 2 mechanism mechanism NN cord-022526-j9kg00qf 802 3 by by IN cord-022526-j9kg00qf 802 4 which which WDT cord-022526-j9kg00qf 802 5 the the DT cord-022526-j9kg00qf 802 6 normal normal JJ cord-022526-j9kg00qf 802 7 flora flora NNS cord-022526-j9kg00qf 802 8 inhibit inhibit VBP cord-022526-j9kg00qf 802 9 establishment establishment NN cord-022526-j9kg00qf 802 10 of of IN cord-022526-j9kg00qf 802 11 pathogens pathogen NNS cord-022526-j9kg00qf 802 12 is be VBZ cord-022526-j9kg00qf 802 13 by by IN cord-022526-j9kg00qf 802 14 preventing prevent VBG cord-022526-j9kg00qf 802 15 adherence adherence NN cord-022526-j9kg00qf 802 16 of of IN cord-022526-j9kg00qf 802 17 the the DT cord-022526-j9kg00qf 802 18 pathogen pathogen NN cord-022526-j9kg00qf 802 19 to to IN cord-022526-j9kg00qf 802 20 mucosal mucosal JJ cord-022526-j9kg00qf 802 21 cells cell NNS cord-022526-j9kg00qf 802 22 by by IN cord-022526-j9kg00qf 802 23 occupying occupy VBG cord-022526-j9kg00qf 802 24 the the DT cord-022526-j9kg00qf 802 25 site site NN cord-022526-j9kg00qf 802 26 or or CC cord-022526-j9kg00qf 802 27 by by IN cord-022526-j9kg00qf 802 28 stearic stearic JJ cord-022526-j9kg00qf 802 29 hindrance hindrance NN cord-022526-j9kg00qf 802 30 . . . cord-022526-j9kg00qf 803 1 [ [ -LRB- cord-022526-j9kg00qf 803 2 102 102 CD cord-022526-j9kg00qf 803 3 ] ] -RRB- cord-022526-j9kg00qf 803 4 [ [ -LRB- cord-022526-j9kg00qf 803 5 103 103 CD cord-022526-j9kg00qf 803 6 ] ] -RRB- cord-022526-j9kg00qf 803 7 [ [ -LRB- cord-022526-j9kg00qf 803 8 104 104 CD cord-022526-j9kg00qf 803 9 ] ] -RRB- cord-022526-j9kg00qf 803 10 [ [ -LRB- cord-022526-j9kg00qf 803 11 105 105 CD cord-022526-j9kg00qf 803 12 ] ] -RRB- cord-022526-j9kg00qf 803 13 Resident resident JJ cord-022526-j9kg00qf 803 14 microbes microbe NNS cord-022526-j9kg00qf 803 15 also also RB cord-022526-j9kg00qf 803 16 produce produce VBP cord-022526-j9kg00qf 803 17 byproducts byproduct NNS cord-022526-j9kg00qf 803 18 such such JJ cord-022526-j9kg00qf 803 19 as as IN cord-022526-j9kg00qf 803 20 antibacterial antibacterial JJ cord-022526-j9kg00qf 803 21 factors factor NNS cord-022526-j9kg00qf 803 22 that that WDT cord-022526-j9kg00qf 803 23 allow allow VBP cord-022526-j9kg00qf 803 24 symbiosis symbiosis NN cord-022526-j9kg00qf 803 25 rather rather RB cord-022526-j9kg00qf 803 26 than than IN cord-022526-j9kg00qf 803 27 competition competition NN cord-022526-j9kg00qf 803 28 between between IN cord-022526-j9kg00qf 803 29 them -PRON- PRP cord-022526-j9kg00qf 803 30 . . . cord-022526-j9kg00qf 804 1 Another another DT cord-022526-j9kg00qf 804 2 hindrance hindrance NN cord-022526-j9kg00qf 804 3 mechanism mechanism NN cord-022526-j9kg00qf 804 4 is be VBZ cord-022526-j9kg00qf 804 5 production production NN cord-022526-j9kg00qf 804 6 of of IN cord-022526-j9kg00qf 804 7 volatile volatile JJ cord-022526-j9kg00qf 804 8 fatty fatty JJ cord-022526-j9kg00qf 804 9 acids acid NNS cord-022526-j9kg00qf 804 10 by by IN cord-022526-j9kg00qf 804 11 normal normal JJ cord-022526-j9kg00qf 804 12 microbial microbial JJ cord-022526-j9kg00qf 804 13 digestive digestive JJ cord-022526-j9kg00qf 804 14 processes process NNS cord-022526-j9kg00qf 804 15 to to TO cord-022526-j9kg00qf 804 16 create create VB cord-022526-j9kg00qf 804 17 an an DT cord-022526-j9kg00qf 804 18 environment environment NN cord-022526-j9kg00qf 804 19 that that WDT cord-022526-j9kg00qf 804 20 is be VBZ cord-022526-j9kg00qf 804 21 toxic toxic JJ cord-022526-j9kg00qf 804 22 to to IN cord-022526-j9kg00qf 804 23 many many JJ cord-022526-j9kg00qf 804 24 bacterial bacterial JJ cord-022526-j9kg00qf 804 25 populations population NNS cord-022526-j9kg00qf 804 26 , , , cord-022526-j9kg00qf 804 27 particularly particularly RB cord-022526-j9kg00qf 804 28 the the DT cord-022526-j9kg00qf 804 29 Enterobacteriaceae Enterobacteriaceae NNP cord-022526-j9kg00qf 804 30 . . . cord-022526-j9kg00qf 805 1 106 106 CD cord-022526-j9kg00qf 805 2 Disturbances disturbance NNS cord-022526-j9kg00qf 805 3 in in IN cord-022526-j9kg00qf 805 4 motility motility NN cord-022526-j9kg00qf 805 5 patterns pattern NNS cord-022526-j9kg00qf 805 6 occur occur VBP cord-022526-j9kg00qf 805 7 during during IN cord-022526-j9kg00qf 805 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 805 9 diseases disease NNS cord-022526-j9kg00qf 805 10 of of IN cord-022526-j9kg00qf 805 11 the the DT cord-022526-j9kg00qf 805 12 colon colon NN cord-022526-j9kg00qf 805 13 , , , cord-022526-j9kg00qf 805 14 but but CC cord-022526-j9kg00qf 805 15 the the DT cord-022526-j9kg00qf 805 16 role role NN cord-022526-j9kg00qf 805 17 of of IN cord-022526-j9kg00qf 805 18 motility motility NN cord-022526-j9kg00qf 805 19 alterations alteration NNS cord-022526-j9kg00qf 805 20 in in IN cord-022526-j9kg00qf 805 21 the the DT cord-022526-j9kg00qf 805 22 pathogenesis pathogenesis NN cord-022526-j9kg00qf 805 23 of of IN cord-022526-j9kg00qf 805 24 diarrhea diarrhea NN cord-022526-j9kg00qf 805 25 remains remain VBZ cord-022526-j9kg00qf 805 26 unclear unclear JJ cord-022526-j9kg00qf 805 27 . . . cord-022526-j9kg00qf 806 1 Invasive invasive JJ cord-022526-j9kg00qf 806 2 bacteria bacteria NNS cord-022526-j9kg00qf 806 3 cause cause VBP cord-022526-j9kg00qf 806 4 characteristic characteristic JJ cord-022526-j9kg00qf 806 5 motor motor NN cord-022526-j9kg00qf 806 6 patterns pattern NNS cord-022526-j9kg00qf 806 7 in in IN cord-022526-j9kg00qf 806 8 the the DT cord-022526-j9kg00qf 806 9 colon colon NN cord-022526-j9kg00qf 806 10 consisting consist VBG cord-022526-j9kg00qf 806 11 of of IN cord-022526-j9kg00qf 806 12 rapid rapid JJ cord-022526-j9kg00qf 806 13 bursts burst NNS cord-022526-j9kg00qf 806 14 of of IN cord-022526-j9kg00qf 806 15 motor motor NN cord-022526-j9kg00qf 806 16 activity activity NN cord-022526-j9kg00qf 806 17 that that WDT cord-022526-j9kg00qf 806 18 appear appear VBP cord-022526-j9kg00qf 806 19 to to TO cord-022526-j9kg00qf 806 20 decrease decrease VB cord-022526-j9kg00qf 806 21 transit transit NN cord-022526-j9kg00qf 806 22 time time NN cord-022526-j9kg00qf 806 23 through through IN cord-022526-j9kg00qf 806 24 the the DT cord-022526-j9kg00qf 806 25 large large JJ cord-022526-j9kg00qf 806 26 intestine intestine NN cord-022526-j9kg00qf 806 27 . . . cord-022526-j9kg00qf 807 1 The the DT cord-022526-j9kg00qf 807 2 result result NN cord-022526-j9kg00qf 807 3 is be VBZ cord-022526-j9kg00qf 807 4 reduced reduce VBN cord-022526-j9kg00qf 807 5 clearance clearance NN cord-022526-j9kg00qf 807 6 of of IN cord-022526-j9kg00qf 807 7 bacteria bacteria NNS cord-022526-j9kg00qf 807 8 from from IN cord-022526-j9kg00qf 807 9 the the DT cord-022526-j9kg00qf 807 10 large large JJ cord-022526-j9kg00qf 807 11 intestine intestine NN cord-022526-j9kg00qf 807 12 , , , cord-022526-j9kg00qf 807 13 which which WDT cord-022526-j9kg00qf 807 14 may may MD cord-022526-j9kg00qf 807 15 contribute contribute VB cord-022526-j9kg00qf 807 16 to to IN cord-022526-j9kg00qf 807 17 the the DT cord-022526-j9kg00qf 807 18 virulence virulence NN cord-022526-j9kg00qf 807 19 of of IN cord-022526-j9kg00qf 807 20 the the DT cord-022526-j9kg00qf 807 21 organism organism NN cord-022526-j9kg00qf 807 22 . . . cord-022526-j9kg00qf 808 1 107 107 CD cord-022526-j9kg00qf 808 2 Absorption absorption NN cord-022526-j9kg00qf 808 3 of of IN cord-022526-j9kg00qf 808 4 endotoxin endotoxin NN cord-022526-j9kg00qf 808 5 and and CC cord-022526-j9kg00qf 808 6 the the DT cord-022526-j9kg00qf 808 7 release release NN cord-022526-j9kg00qf 808 8 of of IN cord-022526-j9kg00qf 808 9 inflammatory inflammatory JJ cord-022526-j9kg00qf 808 10 mediators mediator NNS cord-022526-j9kg00qf 808 11 such such JJ cord-022526-j9kg00qf 808 12 as as IN cord-022526-j9kg00qf 808 13 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 808 14 disrupts disrupt VBZ cord-022526-j9kg00qf 808 15 the the DT cord-022526-j9kg00qf 808 16 motility motility NN cord-022526-j9kg00qf 808 17 patterns pattern NNS cord-022526-j9kg00qf 808 18 of of IN cord-022526-j9kg00qf 808 19 the the DT cord-022526-j9kg00qf 808 20 large large JJ cord-022526-j9kg00qf 808 21 intestine intestine NN cord-022526-j9kg00qf 808 22 , , , cord-022526-j9kg00qf 808 23 resulting result VBG cord-022526-j9kg00qf 808 24 in in IN cord-022526-j9kg00qf 808 25 less less RBR cord-022526-j9kg00qf 808 26 coordinated coordinated JJ cord-022526-j9kg00qf 808 27 contractions contraction NNS cord-022526-j9kg00qf 808 28 , , , cord-022526-j9kg00qf 808 29 and and CC cord-022526-j9kg00qf 808 30 may may MD cord-022526-j9kg00qf 808 31 contribute contribute VB cord-022526-j9kg00qf 808 32 to to IN cord-022526-j9kg00qf 808 33 the the DT cord-022526-j9kg00qf 808 34 alterations alteration NNS cord-022526-j9kg00qf 808 35 in in IN cord-022526-j9kg00qf 808 36 motility motility NN cord-022526-j9kg00qf 808 37 seen see VBN cord-022526-j9kg00qf 808 38 with with IN cord-022526-j9kg00qf 808 39 invasive invasive JJ cord-022526-j9kg00qf 808 40 bacteria bacteria NNS cord-022526-j9kg00qf 808 41 . . . cord-022526-j9kg00qf 809 1 Although although IN cord-022526-j9kg00qf 809 2 the the DT cord-022526-j9kg00qf 809 3 effect effect NN cord-022526-j9kg00qf 809 4 of of IN cord-022526-j9kg00qf 809 5 endotoxin endotoxin NN cord-022526-j9kg00qf 809 6 and and CC cord-022526-j9kg00qf 809 7 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 809 8 on on IN cord-022526-j9kg00qf 809 9 transit transit NN cord-022526-j9kg00qf 809 10 time time NN cord-022526-j9kg00qf 809 11 is be VBZ cord-022526-j9kg00qf 809 12 not not RB cord-022526-j9kg00qf 809 13 profound profound JJ cord-022526-j9kg00qf 809 14 , , , cord-022526-j9kg00qf 809 15 the the DT cord-022526-j9kg00qf 809 16 disruption disruption NN cord-022526-j9kg00qf 809 17 of of IN cord-022526-j9kg00qf 809 18 coordinated coordinated JJ cord-022526-j9kg00qf 809 19 activity activity NN cord-022526-j9kg00qf 809 20 may may MD cord-022526-j9kg00qf 809 21 play play VB cord-022526-j9kg00qf 809 22 a a DT cord-022526-j9kg00qf 809 23 role role NN cord-022526-j9kg00qf 809 24 in in IN cord-022526-j9kg00qf 809 25 causing cause VBG cord-022526-j9kg00qf 809 26 diarrhea diarrhea NN cord-022526-j9kg00qf 809 27 . . . cord-022526-j9kg00qf 810 1 108 108 CD cord-022526-j9kg00qf 811 1 Thorough thorough JJ cord-022526-j9kg00qf 811 2 mixing mixing NN cord-022526-j9kg00qf 811 3 and and CC cord-022526-j9kg00qf 811 4 prolonged prolonged JJ cord-022526-j9kg00qf 811 5 retention retention NN cord-022526-j9kg00qf 811 6 time time NN cord-022526-j9kg00qf 811 7 of of IN cord-022526-j9kg00qf 811 8 ingesta ingesta NNS cord-022526-j9kg00qf 811 9 are be VBP cord-022526-j9kg00qf 811 10 important important JJ cord-022526-j9kg00qf 811 11 not not RB cord-022526-j9kg00qf 811 12 only only RB cord-022526-j9kg00qf 811 13 in in IN cord-022526-j9kg00qf 811 14 microbial microbial JJ cord-022526-j9kg00qf 811 15 digestion digestion NN cord-022526-j9kg00qf 811 16 of of IN cord-022526-j9kg00qf 811 17 nutrients nutrient NNS cord-022526-j9kg00qf 811 18 but but CC cord-022526-j9kg00qf 811 19 also also RB cord-022526-j9kg00qf 811 20 in in IN cord-022526-j9kg00qf 811 21 absorption absorption NN cord-022526-j9kg00qf 811 22 of of IN cord-022526-j9kg00qf 811 23 microbial microbial JJ cord-022526-j9kg00qf 811 24 byproducts byproduct NNS cord-022526-j9kg00qf 811 25 and and CC cord-022526-j9kg00qf 811 26 fluid fluid NN cord-022526-j9kg00qf 811 27 . . . cord-022526-j9kg00qf 812 1 32 32 CD cord-022526-j9kg00qf 812 2 , , , cord-022526-j9kg00qf 812 3 109 109 CD cord-022526-j9kg00qf 813 1 The the DT cord-022526-j9kg00qf 813 2 ingesta ingesta NNS cord-022526-j9kg00qf 813 3 is be VBZ cord-022526-j9kg00qf 813 4 viscous viscous JJ cord-022526-j9kg00qf 813 5 and and CC cord-022526-j9kg00qf 813 6 therefore therefore RB cord-022526-j9kg00qf 813 7 must must MD cord-022526-j9kg00qf 813 8 be be VB cord-022526-j9kg00qf 813 9 mixed mix VBN cord-022526-j9kg00qf 813 10 to to TO cord-022526-j9kg00qf 813 11 bring bring VB cord-022526-j9kg00qf 813 12 luminal luminal JJ cord-022526-j9kg00qf 813 13 ingesta ingesta NNS cord-022526-j9kg00qf 813 14 in in IN cord-022526-j9kg00qf 813 15 contact contact NN cord-022526-j9kg00qf 813 16 with with IN cord-022526-j9kg00qf 813 17 the the DT cord-022526-j9kg00qf 813 18 mucosa mucosa NN cord-022526-j9kg00qf 813 19 for for IN cord-022526-j9kg00qf 813 20 absorption absorption NN cord-022526-j9kg00qf 813 21 . . . cord-022526-j9kg00qf 814 1 109 109 CD cord-022526-j9kg00qf 815 1 In in IN cord-022526-j9kg00qf 815 2 addition addition NN cord-022526-j9kg00qf 815 3 , , , cord-022526-j9kg00qf 815 4 poor poor JJ cord-022526-j9kg00qf 815 5 mixing mixing NN cord-022526-j9kg00qf 815 6 increases increase VBZ cord-022526-j9kg00qf 815 7 the the DT cord-022526-j9kg00qf 815 8 thickness thickness NN cord-022526-j9kg00qf 815 9 of of IN cord-022526-j9kg00qf 815 10 the the DT cord-022526-j9kg00qf 815 11 unstirred unstirred JJ cord-022526-j9kg00qf 815 12 layer layer NN cord-022526-j9kg00qf 815 13 , , , cord-022526-j9kg00qf 815 14 decreasing decrease VBG cord-022526-j9kg00qf 815 15 contact contact NN cord-022526-j9kg00qf 815 16 of of IN cord-022526-j9kg00qf 815 17 ingesta ingesta NNS cord-022526-j9kg00qf 815 18 with with IN cord-022526-j9kg00qf 815 19 the the DT cord-022526-j9kg00qf 815 20 mucosa mucosa NN cord-022526-j9kg00qf 815 21 and and CC cord-022526-j9kg00qf 815 22 decreasing decrease VBG cord-022526-j9kg00qf 815 23 absorption absorption NN cord-022526-j9kg00qf 815 24 . . . cord-022526-j9kg00qf 816 1 32 32 CD cord-022526-j9kg00qf 816 2 , , , cord-022526-j9kg00qf 816 3 109 109 CD cord-022526-j9kg00qf 816 4 Progressive progressive JJ cord-022526-j9kg00qf 816 5 motility motility NN cord-022526-j9kg00qf 816 6 must must MD cord-022526-j9kg00qf 816 7 be be VB cord-022526-j9kg00qf 816 8 present present JJ cord-022526-j9kg00qf 816 9 , , , cord-022526-j9kg00qf 816 10 however however RB cord-022526-j9kg00qf 816 11 , , , cord-022526-j9kg00qf 816 12 if if IN cord-022526-j9kg00qf 816 13 a a DT cord-022526-j9kg00qf 816 14 diarrheal diarrheal JJ cord-022526-j9kg00qf 816 15 state state NN cord-022526-j9kg00qf 816 16 is be VBZ cord-022526-j9kg00qf 816 17 to to TO cord-022526-j9kg00qf 816 18 occur occur VB cord-022526-j9kg00qf 816 19 . . . cord-022526-j9kg00qf 817 1 32 32 CD cord-022526-j9kg00qf 817 2 , , , cord-022526-j9kg00qf 817 3 109 109 CD cord-022526-j9kg00qf 817 4 Ileus Ileus NNP cord-022526-j9kg00qf 817 5 may may MD cord-022526-j9kg00qf 817 6 be be VB cord-022526-j9kg00qf 817 7 accompanied accompany VBN cord-022526-j9kg00qf 817 8 by by IN cord-022526-j9kg00qf 817 9 increased increase VBN cord-022526-j9kg00qf 817 10 fluid fluid NN cord-022526-j9kg00qf 817 11 in in IN cord-022526-j9kg00qf 817 12 the the DT cord-022526-j9kg00qf 817 13 lumen lumen NN cord-022526-j9kg00qf 817 14 of of IN cord-022526-j9kg00qf 817 15 the the DT cord-022526-j9kg00qf 817 16 large large JJ cord-022526-j9kg00qf 817 17 intestine intestine NN cord-022526-j9kg00qf 817 18 , , , cord-022526-j9kg00qf 817 19 _SP cord-022526-j9kg00qf 817 20 Pyridoxine Pyridoxine NNP cord-022526-j9kg00qf 817 21 , , , cord-022526-j9kg00qf 817 22 folic folic JJ cord-022526-j9kg00qf 817 23 acid acid NN cord-022526-j9kg00qf 817 24 , , , cord-022526-j9kg00qf 817 25 Impairs Impairs NNP cord-022526-j9kg00qf 817 26 cell cell NN cord-022526-j9kg00qf 817 27 - - HYPH cord-022526-j9kg00qf 817 28 mediated mediate VBN cord-022526-j9kg00qf 817 29 immunity immunity NN cord-022526-j9kg00qf 817 30 and and CC cord-022526-j9kg00qf 817 31 vitamin vitamin NN cord-022526-j9kg00qf 817 32 C c NN cord-022526-j9kg00qf 817 33 , , , cord-022526-j9kg00qf 817 34 vitamin vitamin NN cord-022526-j9kg00qf 817 35 E e NN cord-022526-j9kg00qf 817 36 reduces reduce VBZ cord-022526-j9kg00qf 817 37 antibody antibody NN cord-022526-j9kg00qf 817 38 response response NN cord-022526-j9kg00qf 817 39 . . . cord-022526-j9kg00qf 818 1 Vitamin vitamin NN cord-022526-j9kg00qf 818 2 B B NNP cord-022526-j9kg00qf 818 3 6 6 CD cord-022526-j9kg00qf 818 4 Decreases decreases NN cord-022526-j9kg00qf 818 5 lymphocyte lymphocyte NN cord-022526-j9kg00qf 818 6 stimulation stimulation NN cord-022526-j9kg00qf 818 7 response response NN cord-022526-j9kg00qf 818 8 to to IN cord-022526-j9kg00qf 818 9 specific specific JJ cord-022526-j9kg00qf 818 10 mitogens mitogen NNS cord-022526-j9kg00qf 818 11 . . . cord-022526-j9kg00qf 819 1 Zinc Zinc NNP cord-022526-j9kg00qf 819 2 Deficiency deficiency NN cord-022526-j9kg00qf 819 3 affects affect VBZ cord-022526-j9kg00qf 819 4 humoral humoral JJ cord-022526-j9kg00qf 819 5 and and CC cord-022526-j9kg00qf 819 6 cell cell NN cord-022526-j9kg00qf 819 7 - - HYPH cord-022526-j9kg00qf 819 8 mediated mediate VBN cord-022526-j9kg00qf 819 9 immunity immunity NN cord-022526-j9kg00qf 819 10 . . . cord-022526-j9kg00qf 820 1 Iron iron NN cord-022526-j9kg00qf 820 2 Inhibits inhibit VBZ cord-022526-j9kg00qf 820 3 bacterial bacterial JJ cord-022526-j9kg00qf 820 4 multiplication multiplication NN cord-022526-j9kg00qf 820 5 . . . cord-022526-j9kg00qf 821 1 Copper copper NN cord-022526-j9kg00qf 821 2 Depresses depress VBZ cord-022526-j9kg00qf 821 3 antibody antibody NN cord-022526-j9kg00qf 821 4 response response NN cord-022526-j9kg00qf 821 5 . . . cord-022526-j9kg00qf 822 1 Needed need VBN cord-022526-j9kg00qf 822 2 by by IN cord-022526-j9kg00qf 822 3 neutrophils neutrophil NNS cord-022526-j9kg00qf 822 4 and and CC cord-022526-j9kg00qf 822 5 lymphocytes lymphocyte NNS cord-022526-j9kg00qf 822 6 for for IN cord-022526-j9kg00qf 822 7 optimal optimal JJ cord-022526-j9kg00qf 822 8 function function NN cord-022526-j9kg00qf 822 9 , , , cord-022526-j9kg00qf 822 10 which which WDT cord-022526-j9kg00qf 822 11 may may MD cord-022526-j9kg00qf 822 12 be be VB cord-022526-j9kg00qf 822 13 related relate VBN cord-022526-j9kg00qf 822 14 to to IN cord-022526-j9kg00qf 822 15 myeloperoxidase myeloperoxidase NN cord-022526-j9kg00qf 822 16 and and CC cord-022526-j9kg00qf 822 17 ribonucleotidyl ribonucleotidyl NNP cord-022526-j9kg00qf 822 18 reductase reductase NN cord-022526-j9kg00qf 822 19 deficiencies deficiency NNS cord-022526-j9kg00qf 822 20 . . . cord-022526-j9kg00qf 823 1 but but CC cord-022526-j9kg00qf 823 2 without without IN cord-022526-j9kg00qf 823 3 progressive progressive JJ cord-022526-j9kg00qf 823 4 motility motility NN cord-022526-j9kg00qf 823 5 the the DT cord-022526-j9kg00qf 823 6 fluid fluid NN cord-022526-j9kg00qf 823 7 is be VBZ cord-022526-j9kg00qf 823 8 not not RB cord-022526-j9kg00qf 823 9 passed pass VBN cord-022526-j9kg00qf 823 10 . . . cord-022526-j9kg00qf 824 1 Frequently frequently RB cord-022526-j9kg00qf 824 2 , , , cord-022526-j9kg00qf 824 3 acute acute JJ cord-022526-j9kg00qf 824 4 colitis colitis NN cord-022526-j9kg00qf 824 5 causes cause VBZ cord-022526-j9kg00qf 824 6 a a DT cord-022526-j9kg00qf 824 7 period period NN cord-022526-j9kg00qf 824 8 of of IN cord-022526-j9kg00qf 824 9 ileus ileus NN cord-022526-j9kg00qf 824 10 characterized characterize VBN cord-022526-j9kg00qf 824 11 by by IN cord-022526-j9kg00qf 824 12 scant scant JJ cord-022526-j9kg00qf 824 13 stool stool NN cord-022526-j9kg00qf 824 14 . . . cord-022526-j9kg00qf 825 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 825 2 is be VBZ cord-022526-j9kg00qf 825 3 apparent apparent JJ cord-022526-j9kg00qf 825 4 only only RB cord-022526-j9kg00qf 825 5 when when WRB cord-022526-j9kg00qf 825 6 motility motility NN cord-022526-j9kg00qf 825 7 returns return NNS cord-022526-j9kg00qf 825 8 and and CC cord-022526-j9kg00qf 825 9 the the DT cord-022526-j9kg00qf 825 10 ingesta ingesta NNP cord-022526-j9kg00qf 825 11 is be VBZ cord-022526-j9kg00qf 825 12 passed pass VBN cord-022526-j9kg00qf 825 13 . . . cord-022526-j9kg00qf 826 1 Increased increase VBN cord-022526-j9kg00qf 826 2 progressive progressive JJ cord-022526-j9kg00qf 826 3 motility motility NN cord-022526-j9kg00qf 826 4 has have VBZ cord-022526-j9kg00qf 826 5 been be VBN cord-022526-j9kg00qf 826 6 suggested suggest VBN cord-022526-j9kg00qf 826 7 to to TO cord-022526-j9kg00qf 826 8 cause cause VB cord-022526-j9kg00qf 826 9 diarrhea diarrhea NN cord-022526-j9kg00qf 826 10 by by IN cord-022526-j9kg00qf 826 11 decreasing decrease VBG cord-022526-j9kg00qf 826 12 transit transit NN cord-022526-j9kg00qf 826 13 time time NN cord-022526-j9kg00qf 826 14 and and CC cord-022526-j9kg00qf 826 15 is be VBZ cord-022526-j9kg00qf 826 16 thought think VBN cord-022526-j9kg00qf 826 17 to to TO cord-022526-j9kg00qf 826 18 play play VB cord-022526-j9kg00qf 826 19 a a DT cord-022526-j9kg00qf 826 20 role role NN cord-022526-j9kg00qf 826 21 in in IN cord-022526-j9kg00qf 826 22 irritant irritant JJ cord-022526-j9kg00qf 826 23 catharsis catharsis NN cord-022526-j9kg00qf 826 24 and and CC cord-022526-j9kg00qf 826 25 in in IN cord-022526-j9kg00qf 826 26 the the DT cord-022526-j9kg00qf 826 27 mechanism mechanism NN cord-022526-j9kg00qf 826 28 of of IN cord-022526-j9kg00qf 826 29 action action NN cord-022526-j9kg00qf 826 30 of of IN cord-022526-j9kg00qf 826 31 some some DT cord-022526-j9kg00qf 826 32 laxatives laxative NNS cord-022526-j9kg00qf 826 33 . . . cord-022526-j9kg00qf 827 1 110 110 CD cord-022526-j9kg00qf 828 1 Irritation irritation NN cord-022526-j9kg00qf 828 2 and and CC cord-022526-j9kg00qf 828 3 distention distention NN cord-022526-j9kg00qf 828 4 increase increase NN cord-022526-j9kg00qf 828 5 motility motility NN cord-022526-j9kg00qf 828 6 and and CC cord-022526-j9kg00qf 828 7 may may MD cord-022526-j9kg00qf 828 8 well well RB cord-022526-j9kg00qf 828 9 decrease decrease VB cord-022526-j9kg00qf 828 10 transit transit NN cord-022526-j9kg00qf 828 11 time time NN cord-022526-j9kg00qf 828 12 , , , cord-022526-j9kg00qf 828 13 but but CC cord-022526-j9kg00qf 828 14 increased increase VBN cord-022526-j9kg00qf 828 15 secretion secretion NN cord-022526-j9kg00qf 828 16 also also RB cord-022526-j9kg00qf 828 17 is be VBZ cord-022526-j9kg00qf 828 18 thought think VBN cord-022526-j9kg00qf 828 19 to to TO cord-022526-j9kg00qf 828 20 contribute contribute VB cord-022526-j9kg00qf 828 21 to to IN cord-022526-j9kg00qf 828 22 diarrhea diarrhea NN cord-022526-j9kg00qf 828 23 caused cause VBN cord-022526-j9kg00qf 828 24 by by IN cord-022526-j9kg00qf 828 25 these these DT cord-022526-j9kg00qf 828 26 substances substance NNS cord-022526-j9kg00qf 828 27 . . . cord-022526-j9kg00qf 829 1 111 111 CD cord-022526-j9kg00qf 830 1 One one PRP cord-022526-j9kg00qf 830 2 should should MD cord-022526-j9kg00qf 830 3 direct direct VB cord-022526-j9kg00qf 830 4 the the DT cord-022526-j9kg00qf 830 5 clinical clinical JJ cord-022526-j9kg00qf 830 6 investigation investigation NN cord-022526-j9kg00qf 830 7 of of IN cord-022526-j9kg00qf 830 8 malabsorption malabsorption NN cord-022526-j9kg00qf 830 9 at at IN cord-022526-j9kg00qf 830 10 ascertaining ascertain VBG cord-022526-j9kg00qf 830 11 and and CC cord-022526-j9kg00qf 830 12 trying try VBG cord-022526-j9kg00qf 830 13 to to TO cord-022526-j9kg00qf 830 14 localize localize VB cord-022526-j9kg00qf 830 15 the the DT cord-022526-j9kg00qf 830 16 source source NN cord-022526-j9kg00qf 830 17 of of IN cord-022526-j9kg00qf 830 18 the the DT cord-022526-j9kg00qf 830 19 abnormality abnormality NN cord-022526-j9kg00qf 830 20 . . . cord-022526-j9kg00qf 831 1 In in IN cord-022526-j9kg00qf 831 2 medical medical JJ cord-022526-j9kg00qf 831 3 practice practice NN cord-022526-j9kg00qf 831 4 , , , cord-022526-j9kg00qf 831 5 impairment impairment NN cord-022526-j9kg00qf 831 6 of of IN cord-022526-j9kg00qf 831 7 one one CD cord-022526-j9kg00qf 831 8 or or CC cord-022526-j9kg00qf 831 9 more more JJR cord-022526-j9kg00qf 831 10 phases phase NNS cord-022526-j9kg00qf 831 11 of of IN cord-022526-j9kg00qf 831 12 the the DT cord-022526-j9kg00qf 831 13 digestion digestion NN cord-022526-j9kg00qf 831 14 and and CC cord-022526-j9kg00qf 831 15 absorption absorption NN cord-022526-j9kg00qf 831 16 of of IN cord-022526-j9kg00qf 831 17 dietary dietary JJ cord-022526-j9kg00qf 831 18 constituents constituent NNS cord-022526-j9kg00qf 831 19 may may MD cord-022526-j9kg00qf 831 20 precipitate precipitate VB cord-022526-j9kg00qf 831 21 clinical clinical JJ cord-022526-j9kg00qf 831 22 signs sign NNS cord-022526-j9kg00qf 831 23 that that WDT cord-022526-j9kg00qf 831 24 are be VBP cord-022526-j9kg00qf 831 25 associated associate VBN cord-022526-j9kg00qf 831 26 primarily primarily RB cord-022526-j9kg00qf 831 27 with with IN cord-022526-j9kg00qf 831 28 carbohydrate carbohydrate NN cord-022526-j9kg00qf 831 29 , , , cord-022526-j9kg00qf 831 30 protein protein NN cord-022526-j9kg00qf 831 31 , , , cord-022526-j9kg00qf 831 32 or or CC cord-022526-j9kg00qf 831 33 fat fat JJ cord-022526-j9kg00qf 831 34 malabsorption malabsorption NN cord-022526-j9kg00qf 831 35 . . . cord-022526-j9kg00qf 832 1 This this DT cord-022526-j9kg00qf 832 2 level level NN cord-022526-j9kg00qf 832 3 of of IN cord-022526-j9kg00qf 832 4 differentiation differentiation NN cord-022526-j9kg00qf 832 5 is be VBZ cord-022526-j9kg00qf 832 6 not not RB cord-022526-j9kg00qf 832 7 possible possible JJ cord-022526-j9kg00qf 832 8 in in IN cord-022526-j9kg00qf 832 9 the the DT cord-022526-j9kg00qf 832 10 horse horse NN cord-022526-j9kg00qf 832 11 because because IN cord-022526-j9kg00qf 832 12 of of IN cord-022526-j9kg00qf 832 13 the the DT cord-022526-j9kg00qf 832 14 herbivorous herbivorous JJ cord-022526-j9kg00qf 832 15 diet diet NN cord-022526-j9kg00qf 832 16 and and CC cord-022526-j9kg00qf 832 17 the the DT cord-022526-j9kg00qf 832 18 contribution contribution NN cord-022526-j9kg00qf 832 19 of of IN cord-022526-j9kg00qf 832 20 large large JJ cord-022526-j9kg00qf 832 21 intestinal intestinal JJ cord-022526-j9kg00qf 832 22 functions function NNS cord-022526-j9kg00qf 832 23 . . . cord-022526-j9kg00qf 833 1 In in IN cord-022526-j9kg00qf 833 2 human human JJ cord-022526-j9kg00qf 833 3 and and CC cord-022526-j9kg00qf 833 4 small small JJ cord-022526-j9kg00qf 833 5 animal animal NN cord-022526-j9kg00qf 833 6 medicine medicine NN cord-022526-j9kg00qf 833 7 , , , cord-022526-j9kg00qf 833 8 disturbances disturbance NNS cord-022526-j9kg00qf 833 9 in in IN cord-022526-j9kg00qf 833 10 digestive digestive JJ cord-022526-j9kg00qf 833 11 processes process NNS cord-022526-j9kg00qf 833 12 especially especially RB cord-022526-j9kg00qf 833 13 from from IN cord-022526-j9kg00qf 833 14 exocrine exocrine JJ cord-022526-j9kg00qf 833 15 pancreatic pancreatic JJ cord-022526-j9kg00qf 833 16 insufficiency insufficiency NN cord-022526-j9kg00qf 833 17 or or CC cord-022526-j9kg00qf 833 18 reduced reduce VBN cord-022526-j9kg00qf 833 19 intestinal intestinal JJ cord-022526-j9kg00qf 833 20 bile bile NN cord-022526-j9kg00qf 833 21 salt salt NN cord-022526-j9kg00qf 833 22 concentration concentration NN cord-022526-j9kg00qf 833 23 are be VBP cord-022526-j9kg00qf 833 24 principal principal JJ cord-022526-j9kg00qf 833 25 determinants determinant NNS cord-022526-j9kg00qf 833 26 of of IN cord-022526-j9kg00qf 833 27 many many JJ cord-022526-j9kg00qf 833 28 clinical clinical JJ cord-022526-j9kg00qf 833 29 malabsorption malabsorption NN cord-022526-j9kg00qf 833 30 syndromes syndrome NNS cord-022526-j9kg00qf 833 31 . . . cord-022526-j9kg00qf 834 1 The the DT cord-022526-j9kg00qf 834 2 rarity rarity NN cord-022526-j9kg00qf 834 3 of of IN cord-022526-j9kg00qf 834 4 pancreatic pancreatic JJ cord-022526-j9kg00qf 834 5 problems problem NNS cord-022526-j9kg00qf 834 6 in in IN cord-022526-j9kg00qf 834 7 horses horse NNS cord-022526-j9kg00qf 834 8 and and CC cord-022526-j9kg00qf 834 9 the the DT cord-022526-j9kg00qf 834 10 herbivorous herbivorous JJ cord-022526-j9kg00qf 834 11 diet diet NN cord-022526-j9kg00qf 834 12 makes make VBZ cord-022526-j9kg00qf 834 13 maldigestion maldigestion NN cord-022526-j9kg00qf 834 14 less less JJR cord-022526-j9kg00qf 834 15 of of IN cord-022526-j9kg00qf 834 16 a a DT cord-022526-j9kg00qf 834 17 concern concern NN cord-022526-j9kg00qf 834 18 and and CC cord-022526-j9kg00qf 834 19 difficult difficult JJ cord-022526-j9kg00qf 834 20 to to TO cord-022526-j9kg00qf 834 21 pursue pursue VB cord-022526-j9kg00qf 834 22 diagnostically diagnostically RB cord-022526-j9kg00qf 834 23 . . . cord-022526-j9kg00qf 835 1 Nevertheless nevertheless RB cord-022526-j9kg00qf 835 2 , , , cord-022526-j9kg00qf 835 3 maldigestion maldigestion NN cord-022526-j9kg00qf 835 4 undoubtedly undoubtedly RB cord-022526-j9kg00qf 835 5 contributes contribute VBZ cord-022526-j9kg00qf 835 6 to to IN cord-022526-j9kg00qf 835 7 chronic chronic JJ cord-022526-j9kg00qf 835 8 weight weight NN cord-022526-j9kg00qf 835 9 loss loss NN cord-022526-j9kg00qf 835 10 conditions condition NNS cord-022526-j9kg00qf 835 11 in in IN cord-022526-j9kg00qf 835 12 horses horse NNS cord-022526-j9kg00qf 835 13 , , , cord-022526-j9kg00qf 835 14 which which WDT cord-022526-j9kg00qf 835 15 may may MD cord-022526-j9kg00qf 835 16 be be VB cord-022526-j9kg00qf 835 17 significant significant JJ cord-022526-j9kg00qf 835 18 with with IN cord-022526-j9kg00qf 835 19 severe severe JJ cord-022526-j9kg00qf 835 20 infiltrative infiltrative JJ cord-022526-j9kg00qf 835 21 disease disease NN cord-022526-j9kg00qf 835 22 of of IN cord-022526-j9kg00qf 835 23 the the DT cord-022526-j9kg00qf 835 24 small small JJ cord-022526-j9kg00qf 835 25 intestine intestine NN cord-022526-j9kg00qf 835 26 with with IN cord-022526-j9kg00qf 835 27 partial partial JJ cord-022526-j9kg00qf 835 28 to to IN cord-022526-j9kg00qf 835 29 total total JJ cord-022526-j9kg00qf 835 30 villous villous JJ cord-022526-j9kg00qf 835 31 atrophy atrophy NN cord-022526-j9kg00qf 835 32 and and CC cord-022526-j9kg00qf 835 33 flattened flatten VBN cord-022526-j9kg00qf 835 34 mucosa mucosa JJ cord-022526-j9kg00qf 835 35 . . . cord-022526-j9kg00qf 836 1 Impairment impairment NN cord-022526-j9kg00qf 836 2 of of IN cord-022526-j9kg00qf 836 3 digestive digestive JJ cord-022526-j9kg00qf 836 4 processes process NNS cord-022526-j9kg00qf 836 5 may may MD cord-022526-j9kg00qf 836 6 exacerbate exacerbate VB cord-022526-j9kg00qf 836 7 diarrhea diarrhea NN cord-022526-j9kg00qf 836 8 in in IN cord-022526-j9kg00qf 836 9 the the DT cord-022526-j9kg00qf 836 10 suckling suckle VBG cord-022526-j9kg00qf 836 11 foal foal NN cord-022526-j9kg00qf 836 12 through through IN cord-022526-j9kg00qf 836 13 reduced reduce VBN cord-022526-j9kg00qf 836 14 intestinal intestinal JJ cord-022526-j9kg00qf 836 15 bile bile NN cord-022526-j9kg00qf 836 16 salt salt NN cord-022526-j9kg00qf 836 17 concentrations concentration NNS cord-022526-j9kg00qf 836 18 from from IN cord-022526-j9kg00qf 836 19 hepatic hepatic JJ cord-022526-j9kg00qf 836 20 or or CC cord-022526-j9kg00qf 836 21 ileal ileal JJ cord-022526-j9kg00qf 836 22 dysfunction dysfunction NN cord-022526-j9kg00qf 836 23 . . . cord-022526-j9kg00qf 837 1 Malabsorption malabsorption NN cord-022526-j9kg00qf 837 2 is be VBZ cord-022526-j9kg00qf 837 3 not not RB cord-022526-j9kg00qf 837 4 synonymous synonymous JJ cord-022526-j9kg00qf 837 5 with with IN cord-022526-j9kg00qf 837 6 diarrhea diarrhea NN cord-022526-j9kg00qf 837 7 , , , cord-022526-j9kg00qf 837 8 although although IN cord-022526-j9kg00qf 837 9 diarrhea diarrhea NN cord-022526-j9kg00qf 837 10 may may MD cord-022526-j9kg00qf 837 11 be be VB cord-022526-j9kg00qf 837 12 a a DT cord-022526-j9kg00qf 837 13 feature feature NN cord-022526-j9kg00qf 837 14 . . . cord-022526-j9kg00qf 838 1 Adult adult NN cord-022526-j9kg00qf 838 2 horses horse NNS cord-022526-j9kg00qf 838 3 rarely rarely RB cord-022526-j9kg00qf 838 4 exhibit exhibit VBP cord-022526-j9kg00qf 838 5 diarrhea diarrhea NN cord-022526-j9kg00qf 838 6 with with IN cord-022526-j9kg00qf 838 7 small small JJ cord-022526-j9kg00qf 838 8 intestinal intestinal JJ cord-022526-j9kg00qf 838 9 problems problem NNS cord-022526-j9kg00qf 838 10 unless unless IN cord-022526-j9kg00qf 838 11 large large JJ cord-022526-j9kg00qf 838 12 intestinal intestinal JJ cord-022526-j9kg00qf 838 13 involvement involvement NN cord-022526-j9kg00qf 838 14 is be VBZ cord-022526-j9kg00qf 838 15 concomitant concomitant JJ cord-022526-j9kg00qf 838 16 . . . cord-022526-j9kg00qf 839 1 Chronic chronic JJ cord-022526-j9kg00qf 839 2 diarrhea diarrhea NN cord-022526-j9kg00qf 839 3 is be VBZ cord-022526-j9kg00qf 839 4 predominantly predominantly RB cord-022526-j9kg00qf 839 5 a a DT cord-022526-j9kg00qf 839 6 large large JJ cord-022526-j9kg00qf 839 7 intestinal intestinal JJ cord-022526-j9kg00qf 839 8 disorder disorder NN cord-022526-j9kg00qf 839 9 that that WDT cord-022526-j9kg00qf 839 10 reflects reflect VBZ cord-022526-j9kg00qf 839 11 an an DT cord-022526-j9kg00qf 839 12 overload overload NN cord-022526-j9kg00qf 839 13 of of IN cord-022526-j9kg00qf 839 14 water water NN cord-022526-j9kg00qf 839 15 and and CC cord-022526-j9kg00qf 839 16 electrolytes electrolyte NNS cord-022526-j9kg00qf 839 17 and and CC cord-022526-j9kg00qf 839 18 thus thus RB cord-022526-j9kg00qf 839 19 may may MD cord-022526-j9kg00qf 839 20 be be VB cord-022526-j9kg00qf 839 21 considered consider VBN cord-022526-j9kg00qf 839 22 a a DT cord-022526-j9kg00qf 839 23 state state NN cord-022526-j9kg00qf 839 24 of of IN cord-022526-j9kg00qf 839 25 impaired impaired JJ cord-022526-j9kg00qf 839 26 absorption absorption NN cord-022526-j9kg00qf 839 27 . . . cord-022526-j9kg00qf 840 1 Primary primary JJ cord-022526-j9kg00qf 840 2 small small JJ cord-022526-j9kg00qf 840 3 intestinal intestinal JJ cord-022526-j9kg00qf 840 4 disease disease NN cord-022526-j9kg00qf 840 5 is be VBZ cord-022526-j9kg00qf 840 6 more more RBR cord-022526-j9kg00qf 840 7 likely likely JJ cord-022526-j9kg00qf 840 8 to to TO cord-022526-j9kg00qf 840 9 occur occur VB cord-022526-j9kg00qf 840 10 in in IN cord-022526-j9kg00qf 840 11 neonates neonate NNS cord-022526-j9kg00qf 840 12 and and CC cord-022526-j9kg00qf 840 13 young young JJ cord-022526-j9kg00qf 840 14 foals foal NNS cord-022526-j9kg00qf 840 15 . . . cord-022526-j9kg00qf 841 1 For for IN cord-022526-j9kg00qf 841 2 example example NN cord-022526-j9kg00qf 841 3 , , , cord-022526-j9kg00qf 841 4 acquired acquire VBD cord-022526-j9kg00qf 841 5 small small JJ cord-022526-j9kg00qf 841 6 intestinal intestinal JJ cord-022526-j9kg00qf 841 7 brush brush NN cord-022526-j9kg00qf 841 8 border border NN cord-022526-j9kg00qf 841 9 lactase lactase NN cord-022526-j9kg00qf 841 10 deficiency deficiency NN cord-022526-j9kg00qf 841 11 may may MD cord-022526-j9kg00qf 841 12 result result VB cord-022526-j9kg00qf 841 13 in in IN cord-022526-j9kg00qf 841 14 increased increase VBN cord-022526-j9kg00qf 841 15 lactose lactose JJ cord-022526-j9kg00qf 841 16 fermentation fermentation NN cord-022526-j9kg00qf 841 17 in in IN cord-022526-j9kg00qf 841 18 the the DT cord-022526-j9kg00qf 841 19 large large JJ cord-022526-j9kg00qf 841 20 intestine intestine NN cord-022526-j9kg00qf 841 21 and and CC cord-022526-j9kg00qf 841 22 induction induction NN cord-022526-j9kg00qf 841 23 of of IN cord-022526-j9kg00qf 841 24 osmotic osmotic JJ cord-022526-j9kg00qf 841 25 diarrhea diarrhea NN cord-022526-j9kg00qf 841 26 . . . cord-022526-j9kg00qf 842 1 1 1 CD cord-022526-j9kg00qf 842 2 Box Box NNP cord-022526-j9kg00qf 842 3 13.4 13.4 CD cord-022526-j9kg00qf 842 4 - - SYM cord-022526-j9kg00qf 842 5 1 1 CD cord-022526-j9kg00qf 842 6 lists list NNS cord-022526-j9kg00qf 842 7 conditions condition NNS cord-022526-j9kg00qf 842 8 that that WDT cord-022526-j9kg00qf 842 9 have have VBP cord-022526-j9kg00qf 842 10 been be VBN cord-022526-j9kg00qf 842 11 or or CC cord-022526-j9kg00qf 842 12 potentially potentially RB cord-022526-j9kg00qf 842 13 could could MD cord-022526-j9kg00qf 842 14 be be VB cord-022526-j9kg00qf 842 15 associated associate VBN cord-022526-j9kg00qf 842 16 with with IN cord-022526-j9kg00qf 842 17 malabsorption malabsorption NN cord-022526-j9kg00qf 842 18 syndromes syndrome NNS cord-022526-j9kg00qf 842 19 and and CC cord-022526-j9kg00qf 842 20 maldigestion maldigestion NN cord-022526-j9kg00qf 842 21 in in IN cord-022526-j9kg00qf 842 22 the the DT cord-022526-j9kg00qf 842 23 horse horse NN cord-022526-j9kg00qf 842 24 . . . cord-022526-j9kg00qf 843 1 Malabsorption malabsorption NN cord-022526-j9kg00qf 843 2 in in IN cord-022526-j9kg00qf 843 3 horses horse NNS cord-022526-j9kg00qf 843 4 has have VBZ cord-022526-j9kg00qf 843 5 no no DT cord-022526-j9kg00qf 843 6 pathognomonic pathognomonic JJ cord-022526-j9kg00qf 843 7 clinical clinical JJ cord-022526-j9kg00qf 843 8 syndrome syndrome NN cord-022526-j9kg00qf 843 9 . . . cord-022526-j9kg00qf 844 1 Case case NN cord-022526-j9kg00qf 844 2 recognition recognition NN cord-022526-j9kg00qf 844 3 derives derive VBZ cord-022526-j9kg00qf 844 4 from from IN cord-022526-j9kg00qf 844 5 the the DT cord-022526-j9kg00qf 844 6 robust robust JJ cord-022526-j9kg00qf 844 7 investigation investigation NN cord-022526-j9kg00qf 844 8 of of IN cord-022526-j9kg00qf 844 9 horses horse NNS cord-022526-j9kg00qf 844 10 with with IN cord-022526-j9kg00qf 844 11 chronic chronic JJ cord-022526-j9kg00qf 844 12 wasting wasting NN cord-022526-j9kg00qf 844 13 . . . cord-022526-j9kg00qf 845 1 Prevalence prevalence NN cord-022526-j9kg00qf 845 2 is be VBZ cord-022526-j9kg00qf 845 3 unknown unknown JJ cord-022526-j9kg00qf 845 4 . . . cord-022526-j9kg00qf 846 1 No no DT cord-022526-j9kg00qf 846 2 strict strict JJ cord-022526-j9kg00qf 846 3 case case NN cord-022526-j9kg00qf 846 4 definition definition NN cord-022526-j9kg00qf 846 5 exists exist VBZ cord-022526-j9kg00qf 846 6 , , , cord-022526-j9kg00qf 846 7 even even RB cord-022526-j9kg00qf 846 8 for for IN cord-022526-j9kg00qf 846 9 chronic chronic JJ cord-022526-j9kg00qf 846 10 wasting wasting NN cord-022526-j9kg00qf 846 11 . . . cord-022526-j9kg00qf 847 1 Interest interest NN cord-022526-j9kg00qf 847 2 generated generate VBN cord-022526-j9kg00qf 847 3 by by IN cord-022526-j9kg00qf 847 4 unusual unusual JJ cord-022526-j9kg00qf 847 5 clinical clinical JJ cord-022526-j9kg00qf 847 6 test test NN cord-022526-j9kg00qf 847 7 results result NNS cord-022526-j9kg00qf 847 8 and and CC cord-022526-j9kg00qf 847 9 their -PRON- PRP$ cord-022526-j9kg00qf 847 10 related related JJ cord-022526-j9kg00qf 847 11 pathologic pathologic JJ cord-022526-j9kg00qf 847 12 findings finding NNS cord-022526-j9kg00qf 847 13 has have VBZ cord-022526-j9kg00qf 847 14 stimulated stimulate VBN cord-022526-j9kg00qf 847 15 publication publication NN cord-022526-j9kg00qf 847 16 of of IN cord-022526-j9kg00qf 847 17 reports report NNS cord-022526-j9kg00qf 847 18 of of IN cord-022526-j9kg00qf 847 19 cases case NNS cord-022526-j9kg00qf 847 20 considered consider VBN cord-022526-j9kg00qf 847 21 as as IN cord-022526-j9kg00qf 847 22 malabsorption malabsorption NN cord-022526-j9kg00qf 847 23 in in IN cord-022526-j9kg00qf 847 24 horses horse NNS cord-022526-j9kg00qf 847 25 . . . cord-022526-j9kg00qf 848 1 Pathologic pathologic JJ cord-022526-j9kg00qf 848 2 description description NN cord-022526-j9kg00qf 848 3 of of IN cord-022526-j9kg00qf 848 4 the the DT cord-022526-j9kg00qf 848 5 predominant predominant JJ cord-022526-j9kg00qf 848 6 cellular cellular JJ cord-022526-j9kg00qf 848 7 infiltrate infiltrate NN cord-022526-j9kg00qf 848 8 and and CC cord-022526-j9kg00qf 848 9 the the DT cord-022526-j9kg00qf 848 10 pattern pattern NN cord-022526-j9kg00qf 848 11 of of IN cord-022526-j9kg00qf 848 12 intestinal intestinal JJ cord-022526-j9kg00qf 848 13 distribution distribution NN cord-022526-j9kg00qf 848 14 have have VBP cord-022526-j9kg00qf 848 15 resulted result VBN cord-022526-j9kg00qf 848 16 in in IN cord-022526-j9kg00qf 848 17 the the DT cord-022526-j9kg00qf 848 18 classification classification NN cord-022526-j9kg00qf 848 19 of of IN cord-022526-j9kg00qf 848 20 many many JJ cord-022526-j9kg00qf 848 21 conditions condition NNS cord-022526-j9kg00qf 848 22 as as IN cord-022526-j9kg00qf 848 23 representing represent VBG cord-022526-j9kg00qf 848 24 examples example NNS cord-022526-j9kg00qf 848 25 of of IN cord-022526-j9kg00qf 848 26 chronic chronic JJ cord-022526-j9kg00qf 848 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 848 28 bowel bowel NN cord-022526-j9kg00qf 848 29 disease disease NN cord-022526-j9kg00qf 848 30 ( ( -LRB- cord-022526-j9kg00qf 848 31 CIBD CIBD NNP cord-022526-j9kg00qf 848 32 ) ) -RRB- cord-022526-j9kg00qf 848 33 ( ( -LRB- cord-022526-j9kg00qf 848 34 see see VB cord-022526-j9kg00qf 848 35 Box Box NNP cord-022526-j9kg00qf 848 36 13.4 13.4 CD cord-022526-j9kg00qf 848 37 - - HYPH cord-022526-j9kg00qf 848 38 1 1 CD cord-022526-j9kg00qf 848 39 ) ) -RRB- cord-022526-j9kg00qf 848 40 , , , cord-022526-j9kg00qf 848 41 drawing draw VBG cord-022526-j9kg00qf 848 42 analogies analogy NNS cord-022526-j9kg00qf 848 43 from from IN cord-022526-j9kg00qf 848 44 human human JJ cord-022526-j9kg00qf 848 45 medicine medicine NN cord-022526-j9kg00qf 848 46 . . . cord-022526-j9kg00qf 849 1 In in IN cord-022526-j9kg00qf 849 2 the the DT cord-022526-j9kg00qf 849 3 affected affect VBN cord-022526-j9kg00qf 849 4 animal animal NN cord-022526-j9kg00qf 849 5 , , , cord-022526-j9kg00qf 849 6 coexistent coexistent JJ cord-022526-j9kg00qf 849 7 enteric enteric JJ cord-022526-j9kg00qf 849 8 protein protein NN cord-022526-j9kg00qf 849 9 loss loss NN cord-022526-j9kg00qf 849 10 reflecting reflect VBG cord-022526-j9kg00qf 849 11 changes change NNS cord-022526-j9kg00qf 849 12 in in IN cord-022526-j9kg00qf 849 13 mucosal mucosal JJ cord-022526-j9kg00qf 849 14 integrity integrity NN cord-022526-j9kg00qf 849 15 from from IN cord-022526-j9kg00qf 849 16 extensive extensive JJ cord-022526-j9kg00qf 849 17 infiltration infiltration NN cord-022526-j9kg00qf 849 18 and and CC cord-022526-j9kg00qf 849 19 inflammation inflammation NN cord-022526-j9kg00qf 849 20 in in IN cord-022526-j9kg00qf 849 21 the the DT cord-022526-j9kg00qf 849 22 intestinal intestinal JJ cord-022526-j9kg00qf 849 23 tract tract NN cord-022526-j9kg00qf 849 24 is be VBZ cord-022526-j9kg00qf 849 25 likely likely JJ cord-022526-j9kg00qf 849 26 to to TO cord-022526-j9kg00qf 849 27 be be VB cord-022526-j9kg00qf 849 28 more more RBR cord-022526-j9kg00qf 849 29 debilitating debilitating JJ cord-022526-j9kg00qf 849 30 than than IN cord-022526-j9kg00qf 849 31 the the DT cord-022526-j9kg00qf 849 32 malabsorption malabsorption NN cord-022526-j9kg00qf 849 33 . . . cord-022526-j9kg00qf 850 1 The the DT cord-022526-j9kg00qf 850 2 principal principal JJ cord-022526-j9kg00qf 850 3 concern concern NN cord-022526-j9kg00qf 850 4 of of IN cord-022526-j9kg00qf 850 5 the the DT cord-022526-j9kg00qf 850 6 owner owner NN cord-022526-j9kg00qf 850 7 is be VBZ cord-022526-j9kg00qf 850 8 the the DT cord-022526-j9kg00qf 850 9 weight weight NN cord-022526-j9kg00qf 850 10 loss loss NN cord-022526-j9kg00qf 850 11 and and CC cord-022526-j9kg00qf 850 12 poor poor JJ cord-022526-j9kg00qf 850 13 condition condition NN cord-022526-j9kg00qf 850 14 of of IN cord-022526-j9kg00qf 850 15 the the DT cord-022526-j9kg00qf 850 16 horse horse NN cord-022526-j9kg00qf 850 17 . . . cord-022526-j9kg00qf 851 1 Many many JJ cord-022526-j9kg00qf 851 2 clinical clinical JJ cord-022526-j9kg00qf 851 3 examination examination NN cord-022526-j9kg00qf 851 4 findings finding NNS cord-022526-j9kg00qf 851 5 , , , cord-022526-j9kg00qf 851 6 except except IN cord-022526-j9kg00qf 851 7 for for IN cord-022526-j9kg00qf 851 8 body body NN cord-022526-j9kg00qf 851 9 condition condition NN cord-022526-j9kg00qf 851 10 , , , cord-022526-j9kg00qf 851 11 may may MD cord-022526-j9kg00qf 851 12 appear appear VB cord-022526-j9kg00qf 851 13 within within IN cord-022526-j9kg00qf 851 14 normal normal JJ cord-022526-j9kg00qf 851 15 limits limit NNS cord-022526-j9kg00qf 851 16 . . . cord-022526-j9kg00qf 852 1 Investigation investigation NN cord-022526-j9kg00qf 852 2 of of IN cord-022526-j9kg00qf 852 3 the the DT cord-022526-j9kg00qf 852 4 weight weight NN cord-022526-j9kg00qf 852 5 loss loss NN cord-022526-j9kg00qf 852 6 , , , cord-022526-j9kg00qf 852 7 together together RB cord-022526-j9kg00qf 852 8 with with IN cord-022526-j9kg00qf 852 9 the the DT cord-022526-j9kg00qf 852 10 clinical clinical JJ cord-022526-j9kg00qf 852 11 pathologic pathologic JJ cord-022526-j9kg00qf 852 12 findings finding NNS cord-022526-j9kg00qf 852 13 , , , cord-022526-j9kg00qf 852 14 helps help VBZ cord-022526-j9kg00qf 852 15 to to TO cord-022526-j9kg00qf 852 16 eliminate eliminate VB cord-022526-j9kg00qf 852 17 other other JJ cord-022526-j9kg00qf 852 18 more more RBR cord-022526-j9kg00qf 852 19 commonly commonly RB cord-022526-j9kg00qf 852 20 encountered encounter VBN cord-022526-j9kg00qf 852 21 causes cause NNS cord-022526-j9kg00qf 852 22 of of IN cord-022526-j9kg00qf 852 23 wasting wasting NN cord-022526-j9kg00qf 852 24 . . . cord-022526-j9kg00qf 853 1 Box Box NNP cord-022526-j9kg00qf 853 2 13.4 13.4 CD cord-022526-j9kg00qf 853 3 - - SYM cord-022526-j9kg00qf 853 4 2 2 CD cord-022526-j9kg00qf 853 5 lists list NNS cord-022526-j9kg00qf 853 6 clinical clinical JJ cord-022526-j9kg00qf 853 7 signs sign NNS cord-022526-j9kg00qf 853 8 that that WDT cord-022526-j9kg00qf 853 9 may may MD cord-022526-j9kg00qf 853 10 be be VB cord-022526-j9kg00qf 853 11 associated associate VBN cord-022526-j9kg00qf 853 12 with with IN cord-022526-j9kg00qf 853 13 malabsorption malabsorption NN cord-022526-j9kg00qf 853 14 syndromes syndrome NNS cord-022526-j9kg00qf 853 15 . . . cord-022526-j9kg00qf 854 1 No no DT cord-022526-j9kg00qf 854 2 characteristic characteristic JJ cord-022526-j9kg00qf 854 3 clinical clinical JJ cord-022526-j9kg00qf 854 4 pathologic pathologic JJ cord-022526-j9kg00qf 854 5 profile profile NN cord-022526-j9kg00qf 854 6 of of IN cord-022526-j9kg00qf 854 7 malabsorption malabsorption NN cord-022526-j9kg00qf 854 8 exists exist VBZ cord-022526-j9kg00qf 854 9 . . . cord-022526-j9kg00qf 855 1 Findings finding NNS cord-022526-j9kg00qf 855 2 relate relate VBP cord-022526-j9kg00qf 855 3 to to IN cord-022526-j9kg00qf 855 4 the the DT cord-022526-j9kg00qf 855 5 stage stage NN cord-022526-j9kg00qf 855 6 of of IN cord-022526-j9kg00qf 855 7 the the DT cord-022526-j9kg00qf 855 8 underlying underlie VBG cord-022526-j9kg00qf 855 9 disease disease NN cord-022526-j9kg00qf 855 10 process process NN cord-022526-j9kg00qf 855 11 and and CC cord-022526-j9kg00qf 855 12 intercurrent intercurrent NN cord-022526-j9kg00qf 855 13 problems problem NNS cord-022526-j9kg00qf 855 14 . . . cord-022526-j9kg00qf 856 1 The the DT cord-022526-j9kg00qf 856 2 syndrome syndrome NN cord-022526-j9kg00qf 856 3 tends tend VBZ cord-022526-j9kg00qf 856 4 to to TO cord-022526-j9kg00qf 856 5 cause cause VB cord-022526-j9kg00qf 856 6 anemia anemia NN cord-022526-j9kg00qf 856 7 ( ( -LRB- cord-022526-j9kg00qf 856 8 normocytic normocytic JJ cord-022526-j9kg00qf 856 9 , , , cord-022526-j9kg00qf 856 10 normochromic normochromic NNP cord-022526-j9kg00qf 856 11 ) ) -RRB- cord-022526-j9kg00qf 856 12 and and CC cord-022526-j9kg00qf 856 13 neutrophilia neutrophilia NNP cord-022526-j9kg00qf 856 14 . . . cord-022526-j9kg00qf 857 1 Hemolytic hemolytic JJ cord-022526-j9kg00qf 857 2 or or CC cord-022526-j9kg00qf 857 3 macrocytic macrocytic JJ cord-022526-j9kg00qf 857 4 anemia anemia NN cord-022526-j9kg00qf 857 5 and and CC cord-022526-j9kg00qf 857 6 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 857 7 have have VBP cord-022526-j9kg00qf 857 8 been be VBN cord-022526-j9kg00qf 857 9 observed observe VBN cord-022526-j9kg00qf 857 10 in in IN cord-022526-j9kg00qf 857 11 alimentary alimentary JJ cord-022526-j9kg00qf 857 12 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 857 13 . . . cord-022526-j9kg00qf 858 1 Lymphocytosis Lymphocytosis NNP cord-022526-j9kg00qf 858 2 ( ( -LRB- cord-022526-j9kg00qf 858 3 leukemia leukemia NN cord-022526-j9kg00qf 858 4 ) ) -RRB- cord-022526-j9kg00qf 858 5 rarely rarely RB cord-022526-j9kg00qf 858 6 is be VBZ cord-022526-j9kg00qf 858 7 encountered encounter VBN cord-022526-j9kg00qf 858 8 . . . cord-022526-j9kg00qf 859 1 Eosinophilia Eosinophilia NNP cord-022526-j9kg00qf 859 2 is be VBZ cord-022526-j9kg00qf 859 3 uncommon uncommon JJ cord-022526-j9kg00qf 859 4 even even RB cord-022526-j9kg00qf 859 5 with with IN cord-022526-j9kg00qf 859 6 suspected suspect VBN cord-022526-j9kg00qf 859 7 immune immune NN cord-022526-j9kg00qf 859 8 - - HYPH cord-022526-j9kg00qf 859 9 mediated mediate VBN cord-022526-j9kg00qf 859 10 conditions condition NNS cord-022526-j9kg00qf 859 11 and and CC cord-022526-j9kg00qf 859 12 widespread widespread JJ cord-022526-j9kg00qf 859 13 tissue tissue NN cord-022526-j9kg00qf 859 14 eosinophilia eosinophilia NN cord-022526-j9kg00qf 859 15 . . . cord-022526-j9kg00qf 860 1 Many many JJ cord-022526-j9kg00qf 860 2 animals animal NNS cord-022526-j9kg00qf 860 3 are be VBP cord-022526-j9kg00qf 860 4 hypoalbuminemic hypoalbuminemic NNP cord-022526-j9kg00qf 860 5 and and CC cord-022526-j9kg00qf 860 6 hypoproteinemic hypoproteinemic NNP cord-022526-j9kg00qf 860 7 ; ; : cord-022526-j9kg00qf 860 8 horses horse NNS cord-022526-j9kg00qf 860 9 with with IN cord-022526-j9kg00qf 860 10 alimentary alimentary JJ cord-022526-j9kg00qf 860 11 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 860 12 may may MD cord-022526-j9kg00qf 860 13 exhibit exhibit VB cord-022526-j9kg00qf 860 14 hyperproteinemia hyperproteinemia NN cord-022526-j9kg00qf 860 15 and and CC cord-022526-j9kg00qf 860 16 hypergammaglobulinemia hypergammaglobulinemia NNP cord-022526-j9kg00qf 860 17 . . . cord-022526-j9kg00qf 861 1 Serum serum NN cord-022526-j9kg00qf 861 2 or or CC cord-022526-j9kg00qf 861 3 plasma plasma NN cord-022526-j9kg00qf 861 4 may may MD cord-022526-j9kg00qf 861 5 be be VB cord-022526-j9kg00qf 861 6 lipemic lipemic JJ cord-022526-j9kg00qf 861 7 . . . cord-022526-j9kg00qf 862 1 The the DT cord-022526-j9kg00qf 862 2 clinician clinician NN cord-022526-j9kg00qf 862 3 may may MD cord-022526-j9kg00qf 862 4 find find VB cord-022526-j9kg00qf 862 5 elevated elevated JJ cord-022526-j9kg00qf 862 6 hepatic hepatic JJ cord-022526-j9kg00qf 862 7 and and CC cord-022526-j9kg00qf 862 8 biliary biliary JJ cord-022526-j9kg00qf 862 9 tract tract NN cord-022526-j9kg00qf 862 10 enzymes enzyme NNS cord-022526-j9kg00qf 862 11 ( ( -LRB- cord-022526-j9kg00qf 862 12 γ γ NN cord-022526-j9kg00qf 862 13 - - HYPH cord-022526-j9kg00qf 862 14 glutamyltransferase glutamyltransferase NN cord-022526-j9kg00qf 862 15 and and CC cord-022526-j9kg00qf 862 16 alkaline alkaline JJ cord-022526-j9kg00qf 862 17 phosphatase phosphatase NN cord-022526-j9kg00qf 862 18 ) ) -RRB- cord-022526-j9kg00qf 862 19 in in IN cord-022526-j9kg00qf 862 20 multisystemic multisystemic JJ cord-022526-j9kg00qf 862 21 conditions condition NNS cord-022526-j9kg00qf 862 22 ; ; : cord-022526-j9kg00qf 862 23 for for IN cord-022526-j9kg00qf 862 24 example example NN cord-022526-j9kg00qf 862 25 , , , cord-022526-j9kg00qf 862 26 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 862 27 granulomatosis granulomatosis NNP cord-022526-j9kg00qf 862 28 ( ( -LRB- cord-022526-j9kg00qf 862 29 multisystemic multisystemic NNP cord-022526-j9kg00qf 862 30 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 862 31 epitheliotropic epitheliotropic NNP cord-022526-j9kg00qf 862 32 disease disease NN cord-022526-j9kg00qf 862 33 ; ; : cord-022526-j9kg00qf 862 34 EG EG NNP cord-022526-j9kg00qf 862 35 [ [ -LRB- cord-022526-j9kg00qf 862 36 MEED MEED NNP cord-022526-j9kg00qf 862 37 ] ] -RRB- cord-022526-j9kg00qf 862 38 ) ) -RRB- cord-022526-j9kg00qf 862 39 . . . cord-022526-j9kg00qf 863 1 Abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 863 2 has have VBZ cord-022526-j9kg00qf 863 3 been be VBN cord-022526-j9kg00qf 863 4 of of IN cord-022526-j9kg00qf 863 5 diagnostic diagnostic JJ cord-022526-j9kg00qf 863 6 value value NN cord-022526-j9kg00qf 863 7 in in IN cord-022526-j9kg00qf 863 8 several several JJ cord-022526-j9kg00qf 863 9 alimentary alimentary JJ cord-022526-j9kg00qf 863 10 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 863 11 cases case NNS cord-022526-j9kg00qf 863 12 , , , cord-022526-j9kg00qf 863 13 but but CC cord-022526-j9kg00qf 863 14 rarely rarely RB cord-022526-j9kg00qf 863 15 in in IN cord-022526-j9kg00qf 863 16 the the DT cord-022526-j9kg00qf 863 17 granulomatous granulomatous JJ cord-022526-j9kg00qf 863 18 conditions condition NNS cord-022526-j9kg00qf 863 19 . . . cord-022526-j9kg00qf 864 1 Ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 864 2 examination examination NN cord-022526-j9kg00qf 864 3 of of IN cord-022526-j9kg00qf 864 4 the the DT cord-022526-j9kg00qf 864 5 abdomen abdomen NN cord-022526-j9kg00qf 864 6 can can MD cord-022526-j9kg00qf 864 7 yield yield VB cord-022526-j9kg00qf 864 8 infomation infomation NN cord-022526-j9kg00qf 864 9 on on IN cord-022526-j9kg00qf 864 10 intestinal intestinal JJ cord-022526-j9kg00qf 864 11 distention distention NN cord-022526-j9kg00qf 864 12 , , , cord-022526-j9kg00qf 864 13 wall wall NN cord-022526-j9kg00qf 864 14 thickness thickness NN cord-022526-j9kg00qf 864 15 , , , cord-022526-j9kg00qf 864 16 and and CC cord-022526-j9kg00qf 864 17 unexplained unexplained JJ cord-022526-j9kg00qf 864 18 masses masse NNS cord-022526-j9kg00qf 864 19 detected detect VBN cord-022526-j9kg00qf 864 20 on on IN cord-022526-j9kg00qf 864 21 rectal rectal JJ cord-022526-j9kg00qf 864 22 palpation palpation NN cord-022526-j9kg00qf 864 23 . . . cord-022526-j9kg00qf 865 1 Rectal rectal JJ cord-022526-j9kg00qf 865 2 biopsy biopsy NN cord-022526-j9kg00qf 865 3 is be VBZ cord-022526-j9kg00qf 865 4 easy easy JJ cord-022526-j9kg00qf 865 5 to to TO cord-022526-j9kg00qf 865 6 perform perform VB cord-022526-j9kg00qf 865 7 and and CC cord-022526-j9kg00qf 865 8 may may MD cord-022526-j9kg00qf 865 9 provide provide VB cord-022526-j9kg00qf 865 10 an an DT cord-022526-j9kg00qf 865 11 indication indication NN cord-022526-j9kg00qf 865 12 of of IN cord-022526-j9kg00qf 865 13 cellular cellular JJ cord-022526-j9kg00qf 865 14 infiltration infiltration NN cord-022526-j9kg00qf 865 15 that that WDT cord-022526-j9kg00qf 865 16 could could MD cord-022526-j9kg00qf 865 17 be be VB cord-022526-j9kg00qf 865 18 present present JJ cord-022526-j9kg00qf 865 19 at at IN cord-022526-j9kg00qf 865 20 more more RBR cord-022526-j9kg00qf 865 21 proximal proximal JJ cord-022526-j9kg00qf 865 22 locations location NNS cord-022526-j9kg00qf 865 23 . . . cord-022526-j9kg00qf 866 1 However however RB cord-022526-j9kg00qf 866 2 , , , cord-022526-j9kg00qf 866 3 pathologists pathologist NNS cord-022526-j9kg00qf 866 4 examine examine VBP cord-022526-j9kg00qf 866 5 few few JJ cord-022526-j9kg00qf 866 6 equine equine JJ cord-022526-j9kg00qf 866 7 rectal rectal JJ cord-022526-j9kg00qf 866 8 samples sample NNS cord-022526-j9kg00qf 866 9 , , , cord-022526-j9kg00qf 866 10 and and CC cord-022526-j9kg00qf 866 11 the the DT cord-022526-j9kg00qf 866 12 interpretation interpretation NN cord-022526-j9kg00qf 866 13 is be VBZ cord-022526-j9kg00qf 866 14 frequently frequently RB cord-022526-j9kg00qf 866 15 equivocal equivocal JJ cord-022526-j9kg00qf 866 16 . . . cord-022526-j9kg00qf 867 1 Adoption adoption NN cord-022526-j9kg00qf 867 2 of of IN cord-022526-j9kg00qf 867 3 standardized standardized JJ cord-022526-j9kg00qf 867 4 grading grading NN cord-022526-j9kg00qf 867 5 or or CC cord-022526-j9kg00qf 867 6 classification classification NN cord-022526-j9kg00qf 867 7 would would MD cord-022526-j9kg00qf 867 8 improve improve VB cord-022526-j9kg00qf 867 9 the the DT cord-022526-j9kg00qf 867 10 diagnostic diagnostic JJ cord-022526-j9kg00qf 867 11 value value NN cord-022526-j9kg00qf 867 12 . . . cord-022526-j9kg00qf 868 1 A a DT cord-022526-j9kg00qf 868 2 proposed propose VBN cord-022526-j9kg00qf 868 3 classification classification NN cord-022526-j9kg00qf 868 4 system system NN cord-022526-j9kg00qf 868 5 was be VBD cord-022526-j9kg00qf 868 6 based base VBN cord-022526-j9kg00qf 868 7 on on IN cord-022526-j9kg00qf 868 8 a a DT cord-022526-j9kg00qf 868 9 retrospective retrospective JJ cord-022526-j9kg00qf 868 10 study study NN cord-022526-j9kg00qf 868 11 of of IN cord-022526-j9kg00qf 868 12 130 130 CD cord-022526-j9kg00qf 868 13 rectal rectal JJ cord-022526-j9kg00qf 868 14 biopsies biopsy NNS cord-022526-j9kg00qf 868 15 from from IN cord-022526-j9kg00qf 868 16 116 116 CD cord-022526-j9kg00qf 868 17 horses horse NNS cord-022526-j9kg00qf 868 18 ages age NNS cord-022526-j9kg00qf 868 19 1 1 CD cord-022526-j9kg00qf 868 20 to to IN cord-022526-j9kg00qf 868 21 18 18 CD cord-022526-j9kg00qf 868 22 years year NNS cord-022526-j9kg00qf 868 23 with with IN cord-022526-j9kg00qf 868 24 clinical clinical JJ cord-022526-j9kg00qf 868 25 signs sign NNS cord-022526-j9kg00qf 868 26 of of IN cord-022526-j9kg00qf 868 27 intestinal intestinal JJ cord-022526-j9kg00qf 868 28 disease disease NN cord-022526-j9kg00qf 868 29 . . . cord-022526-j9kg00qf 869 1 Necropsy necropsy JJ cord-022526-j9kg00qf 869 2 results result NNS cord-022526-j9kg00qf 869 3 were be VBD cord-022526-j9kg00qf 869 4 studied study VBN cord-022526-j9kg00qf 869 5 from from IN cord-022526-j9kg00qf 869 6 40 40 CD cord-022526-j9kg00qf 869 7 horses horse NNS cord-022526-j9kg00qf 869 8 . . . cord-022526-j9kg00qf 870 1 Biopsy biopsy NN cord-022526-j9kg00qf 870 2 specimens specimen NNS cord-022526-j9kg00qf 870 3 ( ( -LRB- cord-022526-j9kg00qf 870 4 21 21 CD cord-022526-j9kg00qf 870 5 horses horse NNS cord-022526-j9kg00qf 870 6 ) ) -RRB- cord-022526-j9kg00qf 870 7 and and CC cord-022526-j9kg00qf 870 8 necropsy necropsy JJ cord-022526-j9kg00qf 870 9 rectal rectal JJ cord-022526-j9kg00qf 870 10 tissue tissue NN cord-022526-j9kg00qf 870 11 ( ( -LRB- cord-022526-j9kg00qf 870 12 9 9 CD cord-022526-j9kg00qf 870 13 horses horse NNS cord-022526-j9kg00qf 870 14 ) ) -RRB- cord-022526-j9kg00qf 870 15 from from IN cord-022526-j9kg00qf 870 16 30 30 CD cord-022526-j9kg00qf 870 17 horses horse NNS cord-022526-j9kg00qf 870 18 ages age NNS cord-022526-j9kg00qf 870 19 4 4 CD cord-022526-j9kg00qf 870 20 to to TO cord-022526-j9kg00qf 870 21 22 22 CD cord-022526-j9kg00qf 870 22 years year NNS cord-022526-j9kg00qf 870 23 served serve VBN cord-022526-j9kg00qf 870 24 as as IN cord-022526-j9kg00qf 870 25 controls control NNS cord-022526-j9kg00qf 870 26 . . . cord-022526-j9kg00qf 871 1 Simple simple JJ cord-022526-j9kg00qf 871 2 proctitis proctitis NN cord-022526-j9kg00qf 871 3 , , , cord-022526-j9kg00qf 871 4 the the DT cord-022526-j9kg00qf 871 5 presence presence NN cord-022526-j9kg00qf 871 6 of of IN cord-022526-j9kg00qf 871 7 neutrophils neutrophil NNS cord-022526-j9kg00qf 871 8 in in IN cord-022526-j9kg00qf 871 9 the the DT cord-022526-j9kg00qf 871 10 crypt crypt NN cord-022526-j9kg00qf 871 11 or or CC cord-022526-j9kg00qf 871 12 surface surface NN cord-022526-j9kg00qf 871 13 epithelium epithelium NN cord-022526-j9kg00qf 871 14 , , , cord-022526-j9kg00qf 871 15 was be VBD cord-022526-j9kg00qf 871 16 an an DT cord-022526-j9kg00qf 871 17 abnormal abnormal JJ cord-022526-j9kg00qf 871 18 finding finding NN cord-022526-j9kg00qf 871 19 compared compare VBN cord-022526-j9kg00qf 871 20 with with IN cord-022526-j9kg00qf 871 21 mild mild JJ cord-022526-j9kg00qf 871 22 scattered scatter VBN cord-022526-j9kg00qf 871 23 neutrophil neutrophil NN cord-022526-j9kg00qf 871 24 infiltration infiltration NN cord-022526-j9kg00qf 871 25 in in IN cord-022526-j9kg00qf 871 26 controls control NNS cord-022526-j9kg00qf 871 27 . . . cord-022526-j9kg00qf 872 1 Simple simple JJ cord-022526-j9kg00qf 872 2 proctitis proctitis NN cord-022526-j9kg00qf 872 3 was be VBD cord-022526-j9kg00qf 872 4 found find VBN cord-022526-j9kg00qf 872 5 in in IN cord-022526-j9kg00qf 872 6 association association NN cord-022526-j9kg00qf 872 7 with with IN cord-022526-j9kg00qf 872 8 malignant malignant JJ cord-022526-j9kg00qf 872 9 lymphoma lymphoma NN cord-022526-j9kg00qf 872 10 and and CC cord-022526-j9kg00qf 872 11 other other JJ cord-022526-j9kg00qf 872 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 872 13 disorders disorder NNS cord-022526-j9kg00qf 872 14 . . . cord-022526-j9kg00qf 873 1 Inflammatory inflammatory JJ cord-022526-j9kg00qf 873 2 bowel bowel NN cord-022526-j9kg00qf 873 3 disease disease NN cord-022526-j9kg00qf 873 4 was be VBD cord-022526-j9kg00qf 873 5 diagnosed diagnose VBN cord-022526-j9kg00qf 873 6 from from IN cord-022526-j9kg00qf 873 7 rectal rectal JJ cord-022526-j9kg00qf 873 8 biopsy biopsy NN cord-022526-j9kg00qf 873 9 specimens specimen NNS cord-022526-j9kg00qf 873 10 in in IN cord-022526-j9kg00qf 873 11 6 6 CD cord-022526-j9kg00qf 873 12 of of IN cord-022526-j9kg00qf 873 13 12 12 CD cord-022526-j9kg00qf 873 14 EG EG NNS cord-022526-j9kg00qf 873 15 ( ( -LRB- cord-022526-j9kg00qf 873 16 MEED MEED NNP cord-022526-j9kg00qf 873 17 ) ) -RRB- cord-022526-j9kg00qf 873 18 cases case NNS cord-022526-j9kg00qf 873 19 and and CC cord-022526-j9kg00qf 873 20 4 4 CD cord-022526-j9kg00qf 873 21 of of IN cord-022526-j9kg00qf 873 22 9 9 CD cord-022526-j9kg00qf 873 23 granulomatous granulomatous JJ cord-022526-j9kg00qf 873 24 enteritis enteritis NN cord-022526-j9kg00qf 873 25 cases case NNS cord-022526-j9kg00qf 873 26 confirmed confirm VBN cord-022526-j9kg00qf 873 27 at at IN cord-022526-j9kg00qf 873 28 necropsy necropsy JJ cord-022526-j9kg00qf 873 29 . . . cord-022526-j9kg00qf 874 1 2 2 CD cord-022526-j9kg00qf 874 2 Rectal rectal JJ cord-022526-j9kg00qf 874 3 biopsy biopsy NN cord-022526-j9kg00qf 874 4 aided aid VBD cord-022526-j9kg00qf 874 5 diagnosis diagnosis NN cord-022526-j9kg00qf 874 6 for for IN cord-022526-j9kg00qf 874 7 3 3 CD cord-022526-j9kg00qf 874 8 of of IN cord-022526-j9kg00qf 874 9 7 7 CD cord-022526-j9kg00qf 874 10 horses horse NNS cord-022526-j9kg00qf 874 11 in in IN cord-022526-j9kg00qf 874 12 a a DT cord-022526-j9kg00qf 874 13 series series NN cord-022526-j9kg00qf 874 14 of of IN cord-022526-j9kg00qf 874 15 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 874 16 - - HYPH cord-022526-j9kg00qf 874 17 plasmacytic plasmacytic JJ cord-022526-j9kg00qf 874 18 enterocolitis enterocolitis NN cord-022526-j9kg00qf 874 19 cases case NNS cord-022526-j9kg00qf 874 20 . . . cord-022526-j9kg00qf 875 1 3 3 LS cord-022526-j9kg00qf 875 2 Eosinophils Eosinophils NNP cord-022526-j9kg00qf 875 3 were be VBD cord-022526-j9kg00qf 875 4 demonstrated demonstrate VBN cord-022526-j9kg00qf 875 5 on on IN cord-022526-j9kg00qf 875 6 impression impression NN cord-022526-j9kg00qf 875 7 smears smear NNS cord-022526-j9kg00qf 875 8 of of IN cord-022526-j9kg00qf 875 9 rectal rectal JJ cord-022526-j9kg00qf 875 10 mucosal mucosal JJ cord-022526-j9kg00qf 875 11 biopsies biopsy NNS cord-022526-j9kg00qf 875 12 from from IN cord-022526-j9kg00qf 875 13 1 1 CD cord-022526-j9kg00qf 875 14 of of IN cord-022526-j9kg00qf 875 15 2 2 CD cord-022526-j9kg00qf 875 16 horses horse NNS cord-022526-j9kg00qf 875 17 with with IN cord-022526-j9kg00qf 875 18 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 875 19 enterocolitis enterocolitis NN cord-022526-j9kg00qf 875 20 . . . cord-022526-j9kg00qf 876 1 4 4 LS cord-022526-j9kg00qf 876 2 Skin skin NN cord-022526-j9kg00qf 876 3 biopsies biopsy NNS cord-022526-j9kg00qf 876 4 or or CC cord-022526-j9kg00qf 876 5 ultrasound ultrasound NN cord-022526-j9kg00qf 876 6 - - HYPH cord-022526-j9kg00qf 876 7 guided guide VBN cord-022526-j9kg00qf 876 8 biopsies biopsy NNS cord-022526-j9kg00qf 876 9 of of IN cord-022526-j9kg00qf 876 10 liver liver NN cord-022526-j9kg00qf 876 11 , , , cord-022526-j9kg00qf 876 12 lymph lymph NN cord-022526-j9kg00qf 876 13 node node NN cord-022526-j9kg00qf 876 14 , , , cord-022526-j9kg00qf 876 15 or or CC cord-022526-j9kg00qf 876 16 lung lung NN cord-022526-j9kg00qf 876 17 may may MD cord-022526-j9kg00qf 876 18 reveal reveal VB cord-022526-j9kg00qf 876 19 evidence evidence NN cord-022526-j9kg00qf 876 20 of of IN cord-022526-j9kg00qf 876 21 multisystemic multisystemic JJ cord-022526-j9kg00qf 876 22 disease disease NN cord-022526-j9kg00qf 876 23 . . . cord-022526-j9kg00qf 877 1 One one PRP cord-022526-j9kg00qf 877 2 can can MD cord-022526-j9kg00qf 877 3 obtain obtain VB cord-022526-j9kg00qf 877 4 intestinal intestinal JJ cord-022526-j9kg00qf 877 5 and and CC cord-022526-j9kg00qf 877 6 lymph lymph NN cord-022526-j9kg00qf 877 7 node node NN cord-022526-j9kg00qf 877 8 biopsies biopsy NNS cord-022526-j9kg00qf 877 9 via via IN cord-022526-j9kg00qf 877 10 a a DT cord-022526-j9kg00qf 877 11 standing stand VBG cord-022526-j9kg00qf 877 12 laparotomy laparotomy NN cord-022526-j9kg00qf 877 13 . . . cord-022526-j9kg00qf 878 1 Exploratory exploratory JJ cord-022526-j9kg00qf 878 2 laparotomy laparotomy NN cord-022526-j9kg00qf 878 3 facilitates facilitate VBZ cord-022526-j9kg00qf 878 4 rigorous rigorous JJ cord-022526-j9kg00qf 878 5 inspection inspection NN cord-022526-j9kg00qf 878 6 of of IN cord-022526-j9kg00qf 878 7 the the DT cord-022526-j9kg00qf 878 8 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 878 9 tract tract NN cord-022526-j9kg00qf 878 10 and and CC cord-022526-j9kg00qf 878 11 associated associated JJ cord-022526-j9kg00qf 878 12 organs organ NNS cord-022526-j9kg00qf 878 13 to to TO cord-022526-j9kg00qf 878 14 obtain obtain VB cord-022526-j9kg00qf 878 15 multiple multiple JJ cord-022526-j9kg00qf 878 16 biopsies biopsy NNS cord-022526-j9kg00qf 878 17 from from IN cord-022526-j9kg00qf 878 18 intestinal intestinal JJ cord-022526-j9kg00qf 878 19 sites site NNS cord-022526-j9kg00qf 878 20 and and CC cord-022526-j9kg00qf 878 21 lymph lymph NN cord-022526-j9kg00qf 878 22 nodes node NNS cord-022526-j9kg00qf 878 23 . . . cord-022526-j9kg00qf 879 1 The the DT cord-022526-j9kg00qf 879 2 procedure procedure NN cord-022526-j9kg00qf 879 3 may may MD cord-022526-j9kg00qf 879 4 provide provide VB cord-022526-j9kg00qf 879 5 a a DT cord-022526-j9kg00qf 879 6 diagnosis diagnosis NN cord-022526-j9kg00qf 879 7 , , , cord-022526-j9kg00qf 879 8 enabling enable VBG cord-022526-j9kg00qf 879 9 one one CD cord-022526-j9kg00qf 879 10 to to TO cord-022526-j9kg00qf 879 11 make make VB cord-022526-j9kg00qf 879 12 decisions decision NNS cord-022526-j9kg00qf 879 13 on on IN cord-022526-j9kg00qf 879 14 potential potential JJ cord-022526-j9kg00qf 879 15 treatment treatment NN cord-022526-j9kg00qf 879 16 and and CC cord-022526-j9kg00qf 879 17 management management NN cord-022526-j9kg00qf 879 18 options option NNS cord-022526-j9kg00qf 879 19 . . . cord-022526-j9kg00qf 880 1 Cost cost NN cord-022526-j9kg00qf 880 2 and and CC cord-022526-j9kg00qf 880 3 potential potential JJ cord-022526-j9kg00qf 880 4 postoperative postoperative JJ cord-022526-j9kg00qf 880 5 complications complication NNS cord-022526-j9kg00qf 880 6 may may MD cord-022526-j9kg00qf 880 7 limit limit VB cord-022526-j9kg00qf 880 8 surgical surgical JJ cord-022526-j9kg00qf 880 9 procedures procedure NNS cord-022526-j9kg00qf 880 10 for for IN cord-022526-j9kg00qf 880 11 diagnosis diagnosis NN cord-022526-j9kg00qf 880 12 . . . cord-022526-j9kg00qf 881 1 Laparoscopy Laparoscopy NNP cord-022526-j9kg00qf 881 2 may may MD cord-022526-j9kg00qf 881 3 provide provide VB cord-022526-j9kg00qf 881 4 an an DT cord-022526-j9kg00qf 881 5 alternative alternative NN cord-022526-j9kg00qf 881 6 means mean NNS cord-022526-j9kg00qf 881 7 to to TO cord-022526-j9kg00qf 881 8 facilitate facilitate VB cord-022526-j9kg00qf 881 9 biopsy biopsy NN cord-022526-j9kg00qf 881 10 of of IN cord-022526-j9kg00qf 881 11 certain certain JJ cord-022526-j9kg00qf 881 12 tissues tissue NNS cord-022526-j9kg00qf 881 13 . . . cord-022526-j9kg00qf 882 1 However however RB cord-022526-j9kg00qf 882 2 , , , cord-022526-j9kg00qf 882 3 one one PRP cord-022526-j9kg00qf 882 4 should should MD cord-022526-j9kg00qf 882 5 consider consider VB cord-022526-j9kg00qf 882 6 surgical surgical JJ cord-022526-j9kg00qf 882 7 exploration exploration NN cord-022526-j9kg00qf 882 8 as as IN cord-022526-j9kg00qf 882 9 an an DT cord-022526-j9kg00qf 882 10 option option NN cord-022526-j9kg00qf 882 11 early early RB cord-022526-j9kg00qf 882 12 in in IN cord-022526-j9kg00qf 882 13 the the DT cord-022526-j9kg00qf 882 14 process process NN cord-022526-j9kg00qf 882 15 rather rather RB cord-022526-j9kg00qf 882 16 than than IN cord-022526-j9kg00qf 882 17 as as IN cord-022526-j9kg00qf 882 18 a a DT cord-022526-j9kg00qf 882 19 last last JJ cord-022526-j9kg00qf 882 20 resort resort NN cord-022526-j9kg00qf 882 21 . . . cord-022526-j9kg00qf 883 1 The the DT cord-022526-j9kg00qf 883 2 noninvasive noninvasive JJ cord-022526-j9kg00qf 883 3 breath breath NN cord-022526-j9kg00qf 883 4 hydrogen hydrogen NN cord-022526-j9kg00qf 883 5 test test NN cord-022526-j9kg00qf 883 6 used use VBN cord-022526-j9kg00qf 883 7 to to TO cord-022526-j9kg00qf 883 8 assess assess VB cord-022526-j9kg00qf 883 9 carbohydrate carbohydrate NN cord-022526-j9kg00qf 883 10 malabsorption malabsorption NN cord-022526-j9kg00qf 883 11 in in IN cord-022526-j9kg00qf 883 12 human human JJ cord-022526-j9kg00qf 883 13 beings being NNS cord-022526-j9kg00qf 883 14 has have VBZ cord-022526-j9kg00qf 883 15 not not RB cord-022526-j9kg00qf 883 16 proved prove VBN cord-022526-j9kg00qf 883 17 reliable reliable JJ cord-022526-j9kg00qf 883 18 in in IN cord-022526-j9kg00qf 883 19 equine equine JJ cord-022526-j9kg00qf 883 20 studies study NNS cord-022526-j9kg00qf 883 21 . . . cord-022526-j9kg00qf 884 1 5 5 CD cord-022526-j9kg00qf 884 2 Intestinal intestinal JJ cord-022526-j9kg00qf 884 3 function function NN cord-022526-j9kg00qf 884 4 tests test NNS cord-022526-j9kg00qf 884 5 can can MD cord-022526-j9kg00qf 884 6 provide provide VB cord-022526-j9kg00qf 884 7 a a DT cord-022526-j9kg00qf 884 8 practical practical JJ cord-022526-j9kg00qf 884 9 and and CC cord-022526-j9kg00qf 884 10 inexpensive inexpensive JJ cord-022526-j9kg00qf 884 11 means mean NNS cord-022526-j9kg00qf 884 12 to to TO cord-022526-j9kg00qf 884 13 assess assess VB cord-022526-j9kg00qf 884 14 the the DT cord-022526-j9kg00qf 884 15 absorptive absorptive JJ cord-022526-j9kg00qf 884 16 capability capability NN cord-022526-j9kg00qf 884 17 of of IN cord-022526-j9kg00qf 884 18 the the DT cord-022526-j9kg00qf 884 19 small small JJ cord-022526-j9kg00qf 884 20 intestine intestine NN cord-022526-j9kg00qf 884 21 . . . cord-022526-j9kg00qf 885 1 For for IN cord-022526-j9kg00qf 885 2 clinical clinical JJ cord-022526-j9kg00qf 885 3 practice practice NN cord-022526-j9kg00qf 885 4 purposes purpose NNS cord-022526-j9kg00qf 885 5 this this DT cord-022526-j9kg00qf 885 6 is be VBZ cord-022526-j9kg00qf 885 7 limited limit VBN cord-022526-j9kg00qf 885 8 to to IN cord-022526-j9kg00qf 885 9 carbohydrate carbohydrate NN cord-022526-j9kg00qf 885 10 absorption absorption NN cord-022526-j9kg00qf 885 11 . . . cord-022526-j9kg00qf 886 1 Abnormality abnormality NN cord-022526-j9kg00qf 886 2 of of IN cord-022526-j9kg00qf 886 3 carbohydrate carbohydrate NN cord-022526-j9kg00qf 886 4 absorption absorption NN cord-022526-j9kg00qf 886 5 has have VBZ cord-022526-j9kg00qf 886 6 become become VBN cord-022526-j9kg00qf 886 7 an an DT cord-022526-j9kg00qf 886 8 important important JJ cord-022526-j9kg00qf 886 9 precept precept NN cord-022526-j9kg00qf 886 10 on on IN cord-022526-j9kg00qf 886 11 which which WDT cord-022526-j9kg00qf 886 12 to to TO cord-022526-j9kg00qf 886 13 base base VB cord-022526-j9kg00qf 886 14 a a DT cord-022526-j9kg00qf 886 15 diagnosis diagnosis NN cord-022526-j9kg00qf 886 16 of of IN cord-022526-j9kg00qf 886 17 malabsorption malabsorption NN cord-022526-j9kg00qf 886 18 in in IN cord-022526-j9kg00qf 886 19 the the DT cord-022526-j9kg00qf 886 20 horse horse NN cord-022526-j9kg00qf 886 21 . . . cord-022526-j9kg00qf 887 1 However however RB cord-022526-j9kg00qf 887 2 , , , cord-022526-j9kg00qf 887 3 results result NNS cord-022526-j9kg00qf 887 4 of of IN cord-022526-j9kg00qf 887 5 the the DT cord-022526-j9kg00qf 887 6 oral oral JJ cord-022526-j9kg00qf 887 7 glucose glucose NN cord-022526-j9kg00qf 887 8 tolerance tolerance NN cord-022526-j9kg00qf 887 9 test test NN cord-022526-j9kg00qf 887 10 ( ( -LRB- cord-022526-j9kg00qf 887 11 OGTT OGTT NNP cord-022526-j9kg00qf 887 12 ) ) -RRB- cord-022526-j9kg00qf 887 13 or or CC cord-022526-j9kg00qf 887 14 D d NN cord-022526-j9kg00qf 887 15 - - HYPH cord-022526-j9kg00qf 887 16 xylose xylose NN cord-022526-j9kg00qf 887 17 absorption absorption NN cord-022526-j9kg00qf 887 18 test test NN cord-022526-j9kg00qf 887 19 require require VBP cord-022526-j9kg00qf 887 20 cautious cautious JJ cord-022526-j9kg00qf 887 21 interpretation interpretation NN cord-022526-j9kg00qf 887 22 . . . cord-022526-j9kg00qf 888 1 Pathologic pathologic JJ cord-022526-j9kg00qf 888 2 changes change NNS cord-022526-j9kg00qf 888 3 in in IN cord-022526-j9kg00qf 888 4 the the DT cord-022526-j9kg00qf 888 5 mucosa mucosa JJ cord-022526-j9kg00qf 888 6 and and CC cord-022526-j9kg00qf 888 7 submucosa submucosa NNP cord-022526-j9kg00qf 888 8 must must MD cord-022526-j9kg00qf 888 9 be be VB cord-022526-j9kg00qf 888 10 extensive extensive JJ cord-022526-j9kg00qf 888 11 and and CC cord-022526-j9kg00qf 888 12 widely widely RB cord-022526-j9kg00qf 888 13 distributed distribute VBN cord-022526-j9kg00qf 888 14 to to TO cord-022526-j9kg00qf 888 15 greatly greatly RB cord-022526-j9kg00qf 888 16 affect affect VB cord-022526-j9kg00qf 888 17 the the DT cord-022526-j9kg00qf 888 18 peak peak NN cord-022526-j9kg00qf 888 19 plasma plasma NN cord-022526-j9kg00qf 888 20 concentration concentration NN cord-022526-j9kg00qf 888 21 and and CC cord-022526-j9kg00qf 888 22 shape shape NN cord-022526-j9kg00qf 888 23 of of IN cord-022526-j9kg00qf 888 24 the the DT cord-022526-j9kg00qf 888 25 curve curve NN cord-022526-j9kg00qf 888 26 . . . cord-022526-j9kg00qf 889 1 The the DT cord-022526-j9kg00qf 889 2 tests test NNS cord-022526-j9kg00qf 889 3 are be VBP cord-022526-j9kg00qf 889 4 easy easy JJ cord-022526-j9kg00qf 889 5 to to TO cord-022526-j9kg00qf 889 6 perform perform VB cord-022526-j9kg00qf 889 7 in in IN cord-022526-j9kg00qf 889 8 practice practice NN cord-022526-j9kg00qf 889 9 and and CC cord-022526-j9kg00qf 889 10 require require VB cord-022526-j9kg00qf 889 11 a a DT cord-022526-j9kg00qf 889 12 baseline baseline JJ cord-022526-j9kg00qf 889 13 blood blood NN cord-022526-j9kg00qf 889 14 sample sample NN cord-022526-j9kg00qf 889 15 predosing predosing NN cord-022526-j9kg00qf 889 16 and and CC cord-022526-j9kg00qf 889 17 further further JJ cord-022526-j9kg00qf 889 18 samples sample NNS cord-022526-j9kg00qf 889 19 for for IN cord-022526-j9kg00qf 889 20 up up IN cord-022526-j9kg00qf 889 21 to to TO cord-022526-j9kg00qf 889 22 6 6 CD cord-022526-j9kg00qf 889 23 hours hour NNS cord-022526-j9kg00qf 889 24 after after IN cord-022526-j9kg00qf 889 25 administration administration NN cord-022526-j9kg00qf 889 26 of of IN cord-022526-j9kg00qf 889 27 the the DT cord-022526-j9kg00qf 889 28 solution solution NN cord-022526-j9kg00qf 889 29 . . . cord-022526-j9kg00qf 890 1 Many many JJ cord-022526-j9kg00qf 890 2 commercial commercial JJ cord-022526-j9kg00qf 890 3 laboratories laboratory NNS cord-022526-j9kg00qf 890 4 conduct conduct VBP cord-022526-j9kg00qf 890 5 glucose glucose NN cord-022526-j9kg00qf 890 6 and and CC cord-022526-j9kg00qf 890 7 xylose xylose NN cord-022526-j9kg00qf 890 8 assays assay NNS cord-022526-j9kg00qf 890 9 . . . cord-022526-j9kg00qf 891 1 The the DT cord-022526-j9kg00qf 891 2 immediate immediate JJ cord-022526-j9kg00qf 891 3 dietary dietary JJ cord-022526-j9kg00qf 891 4 history history NN cord-022526-j9kg00qf 891 5 , , , cord-022526-j9kg00qf 891 6 gastric gastric JJ cord-022526-j9kg00qf 891 7 emptying emptying NN cord-022526-j9kg00qf 891 8 rate rate NN cord-022526-j9kg00qf 891 9 , , , cord-022526-j9kg00qf 891 10 intestinal intestinal JJ cord-022526-j9kg00qf 891 11 transit transit NN cord-022526-j9kg00qf 891 12 , , , cord-022526-j9kg00qf 891 13 age age NN cord-022526-j9kg00qf 891 14 , , , cord-022526-j9kg00qf 891 15 and and CC cord-022526-j9kg00qf 891 16 hormonal hormonal JJ cord-022526-j9kg00qf 891 17 effects effect NNS cord-022526-j9kg00qf 891 18 of of IN cord-022526-j9kg00qf 891 19 the the DT cord-022526-j9kg00qf 891 20 horse horse NN cord-022526-j9kg00qf 891 21 influence influence NN cord-022526-j9kg00qf 891 22 glucose glucose NN cord-022526-j9kg00qf 891 23 peak peak NN cord-022526-j9kg00qf 891 24 and and CC cord-022526-j9kg00qf 891 25 curve curve NN cord-022526-j9kg00qf 891 26 shape shape NN cord-022526-j9kg00qf 891 27 . . . cord-022526-j9kg00qf 892 1 Higher high JJR cord-022526-j9kg00qf 892 2 glucose glucose NN cord-022526-j9kg00qf 892 3 peaks peak NNS cord-022526-j9kg00qf 892 4 are be VBP cord-022526-j9kg00qf 892 5 recorded record VBN cord-022526-j9kg00qf 892 6 from from IN cord-022526-j9kg00qf 892 7 healthy healthy JJ cord-022526-j9kg00qf 892 8 animals animal NNS cord-022526-j9kg00qf 892 9 eating eat VBG cord-022526-j9kg00qf 892 10 grass grass NN cord-022526-j9kg00qf 892 11 or or CC cord-022526-j9kg00qf 892 12 hay hay NN cord-022526-j9kg00qf 892 13 than than IN cord-022526-j9kg00qf 892 14 from from IN cord-022526-j9kg00qf 892 15 those those DT cord-022526-j9kg00qf 892 16 eating eat VBG cord-022526-j9kg00qf 892 17 concentrates concentrate NNS cord-022526-j9kg00qf 892 18 . . . cord-022526-j9kg00qf 893 1 Recent recent JJ cord-022526-j9kg00qf 893 2 appetite appetite NN cord-022526-j9kg00qf 893 3 or or CC cord-022526-j9kg00qf 893 4 the the DT cord-022526-j9kg00qf 893 5 level level NN cord-022526-j9kg00qf 893 6 of of IN cord-022526-j9kg00qf 893 7 cachexia cachexia NN cord-022526-j9kg00qf 893 8 may may MD cord-022526-j9kg00qf 893 9 affect affect VB cord-022526-j9kg00qf 893 10 test test NN cord-022526-j9kg00qf 893 11 results result NNS cord-022526-j9kg00qf 893 12 . . . cord-022526-j9kg00qf 894 1 Maximum maximum JJ cord-022526-j9kg00qf 894 2 plasma plasma NN cord-022526-j9kg00qf 894 3 glucose glucose NN cord-022526-j9kg00qf 894 4 level level NN cord-022526-j9kg00qf 894 5 ( ( -LRB- cord-022526-j9kg00qf 894 6 > > NFP cord-022526-j9kg00qf 894 7 85 85 CD cord-022526-j9kg00qf 894 8 % % NN cord-022526-j9kg00qf 894 9 baseline baseline NN cord-022526-j9kg00qf 894 10 ) ) -RRB- cord-022526-j9kg00qf 894 11 is be VBZ cord-022526-j9kg00qf 894 12 reached reach VBN cord-022526-j9kg00qf 894 13 by by IN cord-022526-j9kg00qf 894 14 120 120 CD cord-022526-j9kg00qf 894 15 minutes minute NNS cord-022526-j9kg00qf 894 16 in in IN cord-022526-j9kg00qf 894 17 healthy healthy JJ cord-022526-j9kg00qf 894 18 animals animal NNS cord-022526-j9kg00qf 894 19 given give VBN cord-022526-j9kg00qf 894 20 1 1 CD cord-022526-j9kg00qf 894 21 g g NN cord-022526-j9kg00qf 894 22 glucose glucose NN cord-022526-j9kg00qf 894 23 per per IN cord-022526-j9kg00qf 894 24 kilogram kilogram NN cord-022526-j9kg00qf 894 25 body body NN cord-022526-j9kg00qf 894 26 mass mass NN cord-022526-j9kg00qf 894 27 as as IN cord-022526-j9kg00qf 894 28 a a DT cord-022526-j9kg00qf 894 29 20 20 CD cord-022526-j9kg00qf 894 30 % % NN cord-022526-j9kg00qf 894 31 solution solution NN cord-022526-j9kg00qf 894 32 . . . cord-022526-j9kg00qf 895 1 6 6 CD cord-022526-j9kg00qf 895 2 , , , cord-022526-j9kg00qf 895 3 7 7 CD cord-022526-j9kg00qf 895 4 Break Break NNP cord-022526-j9kg00qf 895 5 points point NNS cord-022526-j9kg00qf 895 6 below below IN cord-022526-j9kg00qf 895 7 which which WDT cord-022526-j9kg00qf 895 8 the the DT cord-022526-j9kg00qf 895 9 probability probability NN cord-022526-j9kg00qf 895 10 increases increase NNS cord-022526-j9kg00qf 895 11 of of IN cord-022526-j9kg00qf 895 12 carbohydrate carbohydrate NN cord-022526-j9kg00qf 895 13 malabsorption malabsorption NN cord-022526-j9kg00qf 895 14 associated associate VBN cord-022526-j9kg00qf 895 15 with with IN cord-022526-j9kg00qf 895 16 intestinal intestinal JJ cord-022526-j9kg00qf 895 17 morphology morphology NN cord-022526-j9kg00qf 895 18 changes change NNS cord-022526-j9kg00qf 895 19 have have VBP cord-022526-j9kg00qf 895 20 been be VBN cord-022526-j9kg00qf 895 21 proposed propose VBN cord-022526-j9kg00qf 895 22 . . . cord-022526-j9kg00qf 896 1 7 7 CD cord-022526-j9kg00qf 897 1 A a DT cord-022526-j9kg00qf 897 2 referral referral JJ cord-022526-j9kg00qf 897 3 population population NN cord-022526-j9kg00qf 897 4 of of IN cord-022526-j9kg00qf 897 5 42 42 CD cord-022526-j9kg00qf 897 6 mature mature JJ cord-022526-j9kg00qf 897 7 horses horse NNS cord-022526-j9kg00qf 897 8 with with IN cord-022526-j9kg00qf 897 9 chronic chronic JJ cord-022526-j9kg00qf 897 10 weight weight NN cord-022526-j9kg00qf 897 11 loss loss NN cord-022526-j9kg00qf 897 12 was be VBD cord-022526-j9kg00qf 897 13 divided divide VBN cord-022526-j9kg00qf 897 14 into into IN cord-022526-j9kg00qf 897 15 three three CD cord-022526-j9kg00qf 897 16 groups group NNS cord-022526-j9kg00qf 897 17 based base VBN cord-022526-j9kg00qf 897 18 on on IN cord-022526-j9kg00qf 897 19 OGTT OGTT NNP cord-022526-j9kg00qf 897 20 results result NNS cord-022526-j9kg00qf 897 21 to to TO cord-022526-j9kg00qf 897 22 determine determine VB cord-022526-j9kg00qf 897 23 if if IN cord-022526-j9kg00qf 897 24 any any DT cord-022526-j9kg00qf 897 25 concurrence concurrence NN cord-022526-j9kg00qf 897 26 with with IN cord-022526-j9kg00qf 897 27 the the DT cord-022526-j9kg00qf 897 28 morphologic morphologic JJ cord-022526-j9kg00qf 897 29 diagnoses diagnosis NNS cord-022526-j9kg00qf 897 30 existed exist VBD cord-022526-j9kg00qf 897 31 . . . cord-022526-j9kg00qf 898 1 Group group NN cord-022526-j9kg00qf 898 2 1 1 CD cord-022526-j9kg00qf 899 1 ( ( -LRB- cord-022526-j9kg00qf 899 2 n n NN cord-022526-j9kg00qf 899 3 = = SYM cord-022526-j9kg00qf 899 4 5 5 CD cord-022526-j9kg00qf 899 5 ) ) -RRB- cord-022526-j9kg00qf 899 6 had have VBD cord-022526-j9kg00qf 899 7 a a DT cord-022526-j9kg00qf 899 8 normal normal JJ cord-022526-j9kg00qf 899 9 OGTT OGTT NNP cord-022526-j9kg00qf 899 10 ( ( -LRB- cord-022526-j9kg00qf 899 11 peak peak NN cord-022526-j9kg00qf 899 12 glucose glucose NN cord-022526-j9kg00qf 899 13 concentration concentration NN cord-022526-j9kg00qf 899 14 at at IN cord-022526-j9kg00qf 899 15 120 120 CD cord-022526-j9kg00qf 899 16 minutes minute NNS cord-022526-j9kg00qf 899 17 > > XX cord-022526-j9kg00qf 899 18 85 85 CD cord-022526-j9kg00qf 899 19 % % NN cord-022526-j9kg00qf 899 20 baseline baseline NN cord-022526-j9kg00qf 899 21 ) ) -RRB- cord-022526-j9kg00qf 899 22 and and CC cord-022526-j9kg00qf 899 23 contained contain VBD cord-022526-j9kg00qf 899 24 animals animal NNS cord-022526-j9kg00qf 899 25 that that WDT cord-022526-j9kg00qf 899 26 had have VBD cord-022526-j9kg00qf 899 27 normal normal JJ cord-022526-j9kg00qf 899 28 small small JJ cord-022526-j9kg00qf 899 29 intestinal intestinal JJ cord-022526-j9kg00qf 899 30 morphology morphology NN cord-022526-j9kg00qf 899 31 , , , cord-022526-j9kg00qf 899 32 and and CC cord-022526-j9kg00qf 899 33 a a DT cord-022526-j9kg00qf 899 34 few few JJ cord-022526-j9kg00qf 899 35 with with IN cord-022526-j9kg00qf 899 36 large large JJ cord-022526-j9kg00qf 899 37 intestinal intestinal JJ cord-022526-j9kg00qf 899 38 lesions lesion NNS cord-022526-j9kg00qf 899 39 . . . cord-022526-j9kg00qf 900 1 Group group NN cord-022526-j9kg00qf 900 2 2 2 CD cord-022526-j9kg00qf 901 1 ( ( -LRB- cord-022526-j9kg00qf 901 2 n n NN cord-022526-j9kg00qf 901 3 = = SYM cord-022526-j9kg00qf 901 4 25 25 CD cord-022526-j9kg00qf 901 5 ) ) -RRB- cord-022526-j9kg00qf 901 6 had have VBD cord-022526-j9kg00qf 901 7 partial partial JJ cord-022526-j9kg00qf 901 8 malabsorption malabsorption NN cord-022526-j9kg00qf 901 9 and and CC cord-022526-j9kg00qf 901 10 included include VBD cord-022526-j9kg00qf 901 11 18 18 CD cord-022526-j9kg00qf 901 12 horses horse NNS cord-022526-j9kg00qf 901 13 with with IN cord-022526-j9kg00qf 901 14 small small JJ cord-022526-j9kg00qf 901 15 intestinal intestinal JJ cord-022526-j9kg00qf 901 16 infiltrative infiltrative JJ cord-022526-j9kg00qf 901 17 disease disease NN cord-022526-j9kg00qf 901 18 that that WDT cord-022526-j9kg00qf 901 19 allowed allow VBD cord-022526-j9kg00qf 901 20 some some DT cord-022526-j9kg00qf 901 21 glucose glucose NN cord-022526-j9kg00qf 901 22 uptake uptake NN cord-022526-j9kg00qf 901 23 . . . cord-022526-j9kg00qf 902 1 Diagnoses diagnosis NNS cord-022526-j9kg00qf 902 2 included include VBD cord-022526-j9kg00qf 902 3 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 902 4 , , , cord-022526-j9kg00qf 902 5 villous villous NNP cord-022526-j9kg00qf 902 6 atrophy atrophy NN cord-022526-j9kg00qf 902 7 , , , cord-022526-j9kg00qf 902 8 granulomatous granulomatous JJ cord-022526-j9kg00qf 902 9 enteritis enteritis NN cord-022526-j9kg00qf 902 10 and and CC cord-022526-j9kg00qf 902 11 EG EG NNP cord-022526-j9kg00qf 902 12 ( ( -LRB- cord-022526-j9kg00qf 902 13 MEED MEED NNP cord-022526-j9kg00qf 902 14 ) ) -RRB- cord-022526-j9kg00qf 902 15 . . . cord-022526-j9kg00qf 903 1 Seven seven CD cord-022526-j9kg00qf 903 2 horses horse NNS cord-022526-j9kg00qf 903 3 had have VBD cord-022526-j9kg00qf 903 4 normal normal JJ cord-022526-j9kg00qf 903 5 small small JJ cord-022526-j9kg00qf 903 6 intestinal intestinal JJ cord-022526-j9kg00qf 903 7 histologic histologic JJ cord-022526-j9kg00qf 903 8 findings finding NNS cord-022526-j9kg00qf 903 9 . . . cord-022526-j9kg00qf 904 1 Peak peak JJ cord-022526-j9kg00qf 904 2 glucose glucose NN cord-022526-j9kg00qf 904 3 concentrations concentration NNS cord-022526-j9kg00qf 904 4 were be VBD cord-022526-j9kg00qf 904 5 less less JJR cord-022526-j9kg00qf 904 6 than than IN cord-022526-j9kg00qf 904 7 85 85 CD cord-022526-j9kg00qf 904 8 % % NN cord-022526-j9kg00qf 904 9 and and CC cord-022526-j9kg00qf 904 10 greater great JJR cord-022526-j9kg00qf 904 11 than than IN cord-022526-j9kg00qf 904 12 15 15 CD cord-022526-j9kg00qf 904 13 % % NN cord-022526-j9kg00qf 904 14 of of IN cord-022526-j9kg00qf 904 15 baseline baseline NN cord-022526-j9kg00qf 904 16 at at IN cord-022526-j9kg00qf 904 17 120 120 CD cord-022526-j9kg00qf 904 18 minutes minute NNS cord-022526-j9kg00qf 904 19 . . . cord-022526-j9kg00qf 905 1 Seventeen seventeen CD cord-022526-j9kg00qf 905 2 horses horse NNS cord-022526-j9kg00qf 905 3 in in IN cord-022526-j9kg00qf 905 4 the the DT cord-022526-j9kg00qf 905 5 group group NN cord-022526-j9kg00qf 905 6 had have VBD cord-022526-j9kg00qf 905 7 large large JJ cord-022526-j9kg00qf 905 8 intestinal intestinal JJ cord-022526-j9kg00qf 905 9 pathologic pathologic JJ cord-022526-j9kg00qf 905 10 conditions condition NNS cord-022526-j9kg00qf 905 11 . . . cord-022526-j9kg00qf 906 1 Group group NN cord-022526-j9kg00qf 906 2 3 3 CD cord-022526-j9kg00qf 906 3 horses horse NNS cord-022526-j9kg00qf 906 4 ( ( -LRB- cord-022526-j9kg00qf 906 5 n n NN cord-022526-j9kg00qf 906 6 = = SYM cord-022526-j9kg00qf 906 7 12 12 CD cord-022526-j9kg00qf 906 8 ) ) -RRB- cord-022526-j9kg00qf 906 9 had have VBD cord-022526-j9kg00qf 906 10 total total JJ cord-022526-j9kg00qf 906 11 malabsorption malabsorption NN cord-022526-j9kg00qf 906 12 ; ; : cord-022526-j9kg00qf 906 13 the the DT cord-022526-j9kg00qf 906 14 peak peak NN cord-022526-j9kg00qf 906 15 concentration concentration NN cord-022526-j9kg00qf 906 16 at at IN cord-022526-j9kg00qf 906 17 120 120 CD cord-022526-j9kg00qf 906 18 minutes minute NNS cord-022526-j9kg00qf 906 19 was be VBD cord-022526-j9kg00qf 906 20 less less JJR cord-022526-j9kg00qf 906 21 than than IN cord-022526-j9kg00qf 906 22 15 15 CD cord-022526-j9kg00qf 906 23 % % NN cord-022526-j9kg00qf 906 24 above above IN cord-022526-j9kg00qf 906 25 baseline baseline NN cord-022526-j9kg00qf 906 26 . . . cord-022526-j9kg00qf 907 1 These these DT cord-022526-j9kg00qf 907 2 horses horse NNS cord-022526-j9kg00qf 907 3 had have VBD cord-022526-j9kg00qf 907 4 severe severe JJ cord-022526-j9kg00qf 907 5 infiltration infiltration NN cord-022526-j9kg00qf 907 6 throughout throughout IN cord-022526-j9kg00qf 907 7 most most JJS cord-022526-j9kg00qf 907 8 of of IN cord-022526-j9kg00qf 907 9 the the DT cord-022526-j9kg00qf 907 10 small small JJ cord-022526-j9kg00qf 907 11 intestine intestine NN cord-022526-j9kg00qf 907 12 that that WDT cord-022526-j9kg00qf 907 13 was be VBD cord-022526-j9kg00qf 907 14 attributed attribute VBN cord-022526-j9kg00qf 907 15 predominantly predominantly RB cord-022526-j9kg00qf 907 16 to to IN cord-022526-j9kg00qf 907 17 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 907 18 or or CC cord-022526-j9kg00qf 907 19 granulomatous granulomatous JJ cord-022526-j9kg00qf 907 20 enteritis enteritis NN cord-022526-j9kg00qf 907 21 . . . cord-022526-j9kg00qf 908 1 However however RB cord-022526-j9kg00qf 908 2 , , , cord-022526-j9kg00qf 908 3 the the DT cord-022526-j9kg00qf 908 4 test test NN cord-022526-j9kg00qf 908 5 is be VBZ cord-022526-j9kg00qf 908 6 far far RB cord-022526-j9kg00qf 908 7 from from IN cord-022526-j9kg00qf 908 8 definitive definitive JJ cord-022526-j9kg00qf 908 9 ; ; : cord-022526-j9kg00qf 908 10 one one PRP cord-022526-j9kg00qf 908 11 can can MD cord-022526-j9kg00qf 908 12 not not RB cord-022526-j9kg00qf 908 13 assume assume VB cord-022526-j9kg00qf 908 14 a a DT cord-022526-j9kg00qf 908 15 flat flat JJ cord-022526-j9kg00qf 908 16 curve curve NN cord-022526-j9kg00qf 908 17 indicates indicate VBZ cord-022526-j9kg00qf 908 18 malabsorption malabsorption NN cord-022526-j9kg00qf 908 19 and and CC cord-022526-j9kg00qf 908 20 a a DT cord-022526-j9kg00qf 908 21 poor poor JJ cord-022526-j9kg00qf 908 22 prognosis prognosis NN cord-022526-j9kg00qf 908 23 . . . cord-022526-j9kg00qf 909 1 Two two CD cord-022526-j9kg00qf 909 2 horses horse NNS cord-022526-j9kg00qf 909 3 with with IN cord-022526-j9kg00qf 909 4 chronic chronic JJ cord-022526-j9kg00qf 909 5 weight weight NN cord-022526-j9kg00qf 909 6 loss loss NN cord-022526-j9kg00qf 909 7 initially initially RB cord-022526-j9kg00qf 909 8 diagnosed diagnose VBN cord-022526-j9kg00qf 909 9 with with IN cord-022526-j9kg00qf 909 10 malabsorption malabsorption NN cord-022526-j9kg00qf 909 11 based base VBN cord-022526-j9kg00qf 909 12 on on IN cord-022526-j9kg00qf 909 13 flat flat JJ cord-022526-j9kg00qf 909 14 OGTT OGTT NNP cord-022526-j9kg00qf 909 15 curves curve NNS cord-022526-j9kg00qf 909 16 subsequently subsequently RB cord-022526-j9kg00qf 909 17 showed show VBD cord-022526-j9kg00qf 909 18 more more RBR cord-022526-j9kg00qf 909 19 normal normal JJ cord-022526-j9kg00qf 909 20 OGTT ogtt JJ cord-022526-j9kg00qf 909 21 responses response NNS cord-022526-j9kg00qf 909 22 . . . cord-022526-j9kg00qf 910 1 8 8 CD cord-022526-j9kg00qf 910 2 Full full JJ cord-022526-j9kg00qf 910 3 - - HYPH cord-022526-j9kg00qf 910 4 thickness thickness NN cord-022526-j9kg00qf 910 5 intestinal intestinal JJ cord-022526-j9kg00qf 910 6 biopsies biopsy NNS cord-022526-j9kg00qf 910 7 were be VBD cord-022526-j9kg00qf 910 8 unremarkable unremarkable JJ cord-022526-j9kg00qf 910 9 . . . cord-022526-j9kg00qf 911 1 One one CD cord-022526-j9kg00qf 911 2 horse horse NN cord-022526-j9kg00qf 911 3 had have VBD cord-022526-j9kg00qf 911 4 an an DT cord-022526-j9kg00qf 911 5 elevated elevated JJ cord-022526-j9kg00qf 911 6 serum serum NN cord-022526-j9kg00qf 911 7 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 911 8 E e NN cord-022526-j9kg00qf 911 9 to to IN cord-022526-j9kg00qf 911 10 oat oat NN cord-022526-j9kg00qf 911 11 allergen allergen NN cord-022526-j9kg00qf 911 12 . . . cord-022526-j9kg00qf 912 1 Oats oats NN cord-022526-j9kg00qf 912 2 and and CC cord-022526-j9kg00qf 912 3 oat oat NN cord-022526-j9kg00qf 912 4 straw straw NN cord-022526-j9kg00qf 912 5 were be VBD cord-022526-j9kg00qf 912 6 removed remove VBN cord-022526-j9kg00qf 912 7 from from IN cord-022526-j9kg00qf 912 8 access access NN cord-022526-j9kg00qf 912 9 . . . cord-022526-j9kg00qf 913 1 Dexamethasone Dexamethasone NNP cord-022526-j9kg00qf 913 2 was be VBD cord-022526-j9kg00qf 913 3 given give VBN cord-022526-j9kg00qf 913 4 on on IN cord-022526-j9kg00qf 913 5 a a DT cord-022526-j9kg00qf 913 6 tapered tapered JJ cord-022526-j9kg00qf 913 7 protocol protocol NN cord-022526-j9kg00qf 913 8 , , , cord-022526-j9kg00qf 913 9 and and CC cord-022526-j9kg00qf 913 10 a a DT cord-022526-j9kg00qf 913 11 repeat repeat NN cord-022526-j9kg00qf 913 12 OGTT OGTT NNP cord-022526-j9kg00qf 913 13 was be VBD cord-022526-j9kg00qf 913 14 normal normal JJ cord-022526-j9kg00qf 913 15 at at IN cord-022526-j9kg00qf 913 16 18 18 CD cord-022526-j9kg00qf 913 17 months month NNS cord-022526-j9kg00qf 913 18 . . . cord-022526-j9kg00qf 914 1 The the DT cord-022526-j9kg00qf 914 2 other other JJ cord-022526-j9kg00qf 914 3 horse horse NN cord-022526-j9kg00qf 914 4 received receive VBD cord-022526-j9kg00qf 914 5 oral oral JJ cord-022526-j9kg00qf 914 6 probiotics probiotic NNS cord-022526-j9kg00qf 914 7 to to TO cord-022526-j9kg00qf 914 8 counter counter VB cord-022526-j9kg00qf 914 9 suspected suspect VBN cord-022526-j9kg00qf 914 10 small small JJ cord-022526-j9kg00qf 914 11 intestinal intestinal JJ cord-022526-j9kg00qf 914 12 bacterial bacterial JJ cord-022526-j9kg00qf 914 13 overgrowth overgrowth NN cord-022526-j9kg00qf 914 14 , , , cord-022526-j9kg00qf 914 15 was be VBD cord-022526-j9kg00qf 914 16 clinically clinically RB cord-022526-j9kg00qf 914 17 normal normal JJ cord-022526-j9kg00qf 914 18 in in IN cord-022526-j9kg00qf 914 19 2 2 CD cord-022526-j9kg00qf 914 20 months month NNS cord-022526-j9kg00qf 914 21 , , , cord-022526-j9kg00qf 914 22 and and CC cord-022526-j9kg00qf 914 23 had have VBD cord-022526-j9kg00qf 914 24 an an DT cord-022526-j9kg00qf 914 25 improved improve VBN cord-022526-j9kg00qf 914 26 OGTT OGTT NNP cord-022526-j9kg00qf 914 27 with with IN cord-022526-j9kg00qf 914 28 a a DT cord-022526-j9kg00qf 914 29 60 60 CD cord-022526-j9kg00qf 914 30 minute minute NN cord-022526-j9kg00qf 914 31 peak peak NN cord-022526-j9kg00qf 914 32 . . . cord-022526-j9kg00qf 915 1 Therefore therefore RB cord-022526-j9kg00qf 915 2 malabsorption malabsorption NN cord-022526-j9kg00qf 915 3 , , , cord-022526-j9kg00qf 915 4 as as IN cord-022526-j9kg00qf 915 5 defined define VBN cord-022526-j9kg00qf 915 6 by by IN cord-022526-j9kg00qf 915 7 an an DT cord-022526-j9kg00qf 915 8 absorption absorption NN cord-022526-j9kg00qf 915 9 test test NN cord-022526-j9kg00qf 915 10 and and CC cord-022526-j9kg00qf 915 11 weight weight NN cord-022526-j9kg00qf 915 12 loss loss NN cord-022526-j9kg00qf 915 13 , , , cord-022526-j9kg00qf 915 14 may may MD cord-022526-j9kg00qf 915 15 occur occur VB cord-022526-j9kg00qf 915 16 in in IN cord-022526-j9kg00qf 915 17 the the DT cord-022526-j9kg00qf 915 18 horse horse NN cord-022526-j9kg00qf 915 19 without without IN cord-022526-j9kg00qf 915 20 significant significant JJ cord-022526-j9kg00qf 915 21 morphologic morphologic JJ cord-022526-j9kg00qf 915 22 changes change NNS cord-022526-j9kg00qf 915 23 in in IN cord-022526-j9kg00qf 915 24 the the DT cord-022526-j9kg00qf 915 25 intestine intestine NN cord-022526-j9kg00qf 915 26 , , , cord-022526-j9kg00qf 915 27 and and CC cord-022526-j9kg00qf 915 28 the the DT cord-022526-j9kg00qf 915 29 condition condition NN cord-022526-j9kg00qf 915 30 may may MD cord-022526-j9kg00qf 915 31 be be VB cord-022526-j9kg00qf 915 32 transient transient JJ cord-022526-j9kg00qf 915 33 . . . cord-022526-j9kg00qf 916 1 Demonstration demonstration NN cord-022526-j9kg00qf 916 2 of of IN cord-022526-j9kg00qf 916 3 carbohydrate carbohydrate NN cord-022526-j9kg00qf 916 4 malabsorption malabsorption NN cord-022526-j9kg00qf 916 5 in in IN cord-022526-j9kg00qf 916 6 16 16 CD cord-022526-j9kg00qf 916 7 of of IN cord-022526-j9kg00qf 916 8 24 24 CD cord-022526-j9kg00qf 916 9 horses horse NNS cord-022526-j9kg00qf 916 10 with with IN cord-022526-j9kg00qf 916 11 chronic chronic JJ cord-022526-j9kg00qf 916 12 diarrhea diarrhea NN cord-022526-j9kg00qf 916 13 showed show VBD cord-022526-j9kg00qf 916 14 poor poor JJ cord-022526-j9kg00qf 916 15 diagnostic diagnostic JJ cord-022526-j9kg00qf 916 16 sensitivity sensitivity NN cord-022526-j9kg00qf 916 17 for for IN cord-022526-j9kg00qf 916 18 small small JJ cord-022526-j9kg00qf 916 19 intestinal intestinal JJ cord-022526-j9kg00qf 916 20 involvement involvement NN cord-022526-j9kg00qf 916 21 . . . cord-022526-j9kg00qf 917 1 Impaired impaired JJ cord-022526-j9kg00qf 917 2 glucose glucose NN cord-022526-j9kg00qf 917 3 absorption absorption NN cord-022526-j9kg00qf 917 4 was be VBD cord-022526-j9kg00qf 917 5 recorded record VBN cord-022526-j9kg00qf 917 6 in in IN cord-022526-j9kg00qf 917 7 horses horse NNS cord-022526-j9kg00qf 917 8 with with IN cord-022526-j9kg00qf 917 9 predominantly predominantly RB cord-022526-j9kg00qf 917 10 large large JJ cord-022526-j9kg00qf 917 11 intestinal intestinal JJ cord-022526-j9kg00qf 917 12 problems problem NNS cord-022526-j9kg00qf 917 13 , , , cord-022526-j9kg00qf 917 14 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 917 15 , , , cord-022526-j9kg00qf 917 16 chronic chronic JJ cord-022526-j9kg00qf 917 17 colitis colitis NN cord-022526-j9kg00qf 917 18 , , , cord-022526-j9kg00qf 917 19 alimentary alimentary JJ cord-022526-j9kg00qf 917 20 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 917 21 , , , cord-022526-j9kg00qf 917 22 and and CC cord-022526-j9kg00qf 917 23 MEED MEED NNP cord-022526-j9kg00qf 917 24 . . . cord-022526-j9kg00qf 918 1 9 9 CD cord-022526-j9kg00qf 919 1 Although although IN cord-022526-j9kg00qf 919 2 prior prior JJ cord-022526-j9kg00qf 919 3 dietary dietary JJ cord-022526-j9kg00qf 919 4 history history NN cord-022526-j9kg00qf 919 5 influences influence NNS cord-022526-j9kg00qf 919 6 peak peak NN cord-022526-j9kg00qf 919 7 plasma plasma NN cord-022526-j9kg00qf 919 8 xylose xylose NN cord-022526-j9kg00qf 919 9 concentration concentration NN cord-022526-j9kg00qf 919 10 , , , cord-022526-j9kg00qf 919 11 xylose xylose NNP cord-022526-j9kg00qf 919 12 is be VBZ cord-022526-j9kg00qf 919 13 not not RB cord-022526-j9kg00qf 919 14 confounded confound VBN cord-022526-j9kg00qf 919 15 by by IN cord-022526-j9kg00qf 919 16 hormonal hormonal JJ cord-022526-j9kg00qf 919 17 effects effect NNS cord-022526-j9kg00qf 919 18 or or CC cord-022526-j9kg00qf 919 19 mucosal mucosal JJ cord-022526-j9kg00qf 919 20 metabolism metabolism NN cord-022526-j9kg00qf 919 21 . . . cord-022526-j9kg00qf 920 1 Gastric gastric JJ cord-022526-j9kg00qf 920 2 emptying emptying NN cord-022526-j9kg00qf 920 3 rate rate NN cord-022526-j9kg00qf 920 4 , , , cord-022526-j9kg00qf 920 5 intestinal intestinal JJ cord-022526-j9kg00qf 920 6 motility motility NN cord-022526-j9kg00qf 920 7 , , , cord-022526-j9kg00qf 920 8 intraluminal intraluminal JJ cord-022526-j9kg00qf 920 9 bacterial bacterial JJ cord-022526-j9kg00qf 920 10 overgrowth overgrowth NN cord-022526-j9kg00qf 920 11 , , , cord-022526-j9kg00qf 920 12 and and CC cord-022526-j9kg00qf 920 13 renal renal JJ cord-022526-j9kg00qf 920 14 clearance clearance NN cord-022526-j9kg00qf 920 15 do do VBP cord-022526-j9kg00qf 920 16 affect affect VB cord-022526-j9kg00qf 920 17 curve curve NN cord-022526-j9kg00qf 920 18 shape shape NN cord-022526-j9kg00qf 920 19 . . . cord-022526-j9kg00qf 921 1 Healthy healthy JJ cord-022526-j9kg00qf 921 2 mares mare NNS cord-022526-j9kg00qf 921 3 not not RB cord-022526-j9kg00qf 921 4 fed feed VBN cord-022526-j9kg00qf 921 5 for for IN cord-022526-j9kg00qf 921 6 up up IN cord-022526-j9kg00qf 921 7 to to TO cord-022526-j9kg00qf 921 8 96 96 CD cord-022526-j9kg00qf 921 9 hours hour NNS cord-022526-j9kg00qf 921 10 had have VBD cord-022526-j9kg00qf 921 11 flatter flat JJR cord-022526-j9kg00qf 921 12 curves curve NNS cord-022526-j9kg00qf 921 13 and and CC cord-022526-j9kg00qf 921 14 a a DT cord-022526-j9kg00qf 921 15 slower slow JJR cord-022526-j9kg00qf 921 16 decrease decrease NN cord-022526-j9kg00qf 921 17 in in IN cord-022526-j9kg00qf 921 18 plasma plasma NN cord-022526-j9kg00qf 921 19 xylose xylose NN cord-022526-j9kg00qf 921 20 than than IN cord-022526-j9kg00qf 921 21 when when WRB cord-022526-j9kg00qf 921 22 deprived deprive VBN cord-022526-j9kg00qf 921 23 for for IN cord-022526-j9kg00qf 921 24 12 12 CD cord-022526-j9kg00qf 921 25 to to TO cord-022526-j9kg00qf 921 26 36 36 CD cord-022526-j9kg00qf 921 27 hours hour NNS cord-022526-j9kg00qf 921 28 . . . cord-022526-j9kg00qf 922 1 10 10 CD cord-022526-j9kg00qf 923 1 Hence hence RB cord-022526-j9kg00qf 923 2 recent recent JJ cord-022526-j9kg00qf 923 3 appetite appetite NN cord-022526-j9kg00qf 923 4 or or CC cord-022526-j9kg00qf 923 5 the the DT cord-022526-j9kg00qf 923 6 level level NN cord-022526-j9kg00qf 923 7 of of IN cord-022526-j9kg00qf 923 8 cachexia cachexia NN cord-022526-j9kg00qf 923 9 may may MD cord-022526-j9kg00qf 923 10 influence influence VB cord-022526-j9kg00qf 923 11 test test NN cord-022526-j9kg00qf 923 12 results result NNS cord-022526-j9kg00qf 923 13 . . . cord-022526-j9kg00qf 924 1 Abnormal abnormal JJ cord-022526-j9kg00qf 924 2 D d NN cord-022526-j9kg00qf 924 3 - - HYPH cord-022526-j9kg00qf 924 4 xylose xylose NN cord-022526-j9kg00qf 924 5 absorption absorption NN cord-022526-j9kg00qf 924 6 represented represent VBN cord-022526-j9kg00qf 924 7 by by IN cord-022526-j9kg00qf 924 8 a a DT cord-022526-j9kg00qf 924 9 flat flat JJ cord-022526-j9kg00qf 924 10 curve curve NN cord-022526-j9kg00qf 924 11 or or CC cord-022526-j9kg00qf 924 12 delayed delay VBN cord-022526-j9kg00qf 924 13 absorption absorption NN cord-022526-j9kg00qf 924 14 is be VBZ cord-022526-j9kg00qf 924 15 considered consider VBN cord-022526-j9kg00qf 924 16 indicative indicative JJ cord-022526-j9kg00qf 924 17 of of IN cord-022526-j9kg00qf 924 18 significant significant JJ cord-022526-j9kg00qf 924 19 jejunal jejunal JJ cord-022526-j9kg00qf 924 20 disease disease NN cord-022526-j9kg00qf 924 21 and and CC cord-022526-j9kg00qf 924 22 has have VBZ cord-022526-j9kg00qf 924 23 been be VBN cord-022526-j9kg00qf 924 24 observed observe VBN cord-022526-j9kg00qf 924 25 with with IN cord-022526-j9kg00qf 924 26 most most JJS cord-022526-j9kg00qf 924 27 examples example NNS cord-022526-j9kg00qf 924 28 of of IN cord-022526-j9kg00qf 924 29 CIBD CIBD NNP cord-022526-j9kg00qf 924 30 , , , cord-022526-j9kg00qf 924 31 parasitism parasitism NN cord-022526-j9kg00qf 924 32 , , , cord-022526-j9kg00qf 924 33 and and CC cord-022526-j9kg00qf 924 34 idiopathic idiopathic JJ cord-022526-j9kg00qf 924 35 villous villous JJ cord-022526-j9kg00qf 924 36 atrophy atrophy NN cord-022526-j9kg00qf 924 37 . . . cord-022526-j9kg00qf 925 1 11 11 CD cord-022526-j9kg00qf 925 2 , , , cord-022526-j9kg00qf 925 3 12 12 CD cord-022526-j9kg00qf 925 4 Ponies pony NNS cord-022526-j9kg00qf 925 5 may may MD cord-022526-j9kg00qf 925 6 have have VB cord-022526-j9kg00qf 925 7 lower low JJR cord-022526-j9kg00qf 925 8 peak peak NN cord-022526-j9kg00qf 925 9 D d NN cord-022526-j9kg00qf 925 10 - - HYPH cord-022526-j9kg00qf 925 11 xylose xylose NN cord-022526-j9kg00qf 925 12 concentrations concentration NNS cord-022526-j9kg00qf 925 13 at at IN cord-022526-j9kg00qf 925 14 60 60 CD cord-022526-j9kg00qf 925 15 and and CC cord-022526-j9kg00qf 925 16 90 90 CD cord-022526-j9kg00qf 925 17 minutes minute NNS cord-022526-j9kg00qf 925 18 than than IN cord-022526-j9kg00qf 925 19 horses horse NNS cord-022526-j9kg00qf 925 20 , , , cord-022526-j9kg00qf 925 21 although although IN cord-022526-j9kg00qf 925 22 the the DT cord-022526-j9kg00qf 925 23 range range NN cord-022526-j9kg00qf 925 24 of of IN cord-022526-j9kg00qf 925 25 peak peak NN cord-022526-j9kg00qf 925 26 values value NNS cord-022526-j9kg00qf 925 27 at at IN cord-022526-j9kg00qf 925 28 the the DT cord-022526-j9kg00qf 925 29 test test NN cord-022526-j9kg00qf 925 30 dosage dosage NN cord-022526-j9kg00qf 925 31 ( ( -LRB- cord-022526-j9kg00qf 925 32 0.5 0.5 CD cord-022526-j9kg00qf 925 33 g g NN cord-022526-j9kg00qf 925 34 D d NN cord-022526-j9kg00qf 925 35 - - HYPH cord-022526-j9kg00qf 925 36 xylose xylose NN cord-022526-j9kg00qf 925 37 per per IN cord-022526-j9kg00qf 925 38 kilogram kilogram NN cord-022526-j9kg00qf 925 39 body body NN cord-022526-j9kg00qf 925 40 mass mass NN cord-022526-j9kg00qf 925 41 in in IN cord-022526-j9kg00qf 925 42 a a DT cord-022526-j9kg00qf 925 43 10 10 CD cord-022526-j9kg00qf 925 44 % % NN cord-022526-j9kg00qf 925 45 solution solution NN cord-022526-j9kg00qf 925 46 ) ) -RRB- cord-022526-j9kg00qf 925 47 is be VBZ cord-022526-j9kg00qf 925 48 wide wide JJ cord-022526-j9kg00qf 925 49 . . . cord-022526-j9kg00qf 926 1 Potentially potentially RB cord-022526-j9kg00qf 926 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 926 3 discriminatory discriminatory JJ cord-022526-j9kg00qf 926 4 cut cut NN cord-022526-j9kg00qf 926 5 off off RP cord-022526-j9kg00qf 926 6 points point NNS cord-022526-j9kg00qf 926 7 for for IN cord-022526-j9kg00qf 926 8 peak peak NN cord-022526-j9kg00qf 926 9 plasma plasma NN cord-022526-j9kg00qf 926 10 xylose xylose NN cord-022526-j9kg00qf 926 11 concentrations concentration NNS cord-022526-j9kg00qf 926 12 have have VBP cord-022526-j9kg00qf 926 13 not not RB cord-022526-j9kg00qf 926 14 been be VBN cord-022526-j9kg00qf 926 15 determined determine VBN cord-022526-j9kg00qf 926 16 . . . cord-022526-j9kg00qf 927 1 Abnormal abnormal JJ cord-022526-j9kg00qf 927 2 absorption absorption NN cord-022526-j9kg00qf 927 3 curves curve NNS cord-022526-j9kg00qf 927 4 have have VBP cord-022526-j9kg00qf 927 5 been be VBN cord-022526-j9kg00qf 927 6 detected detect VBN cord-022526-j9kg00qf 927 7 in in IN cord-022526-j9kg00qf 927 8 the the DT cord-022526-j9kg00qf 927 9 absence absence NN cord-022526-j9kg00qf 927 10 of of IN cord-022526-j9kg00qf 927 11 small small JJ cord-022526-j9kg00qf 927 12 intestinal intestinal JJ cord-022526-j9kg00qf 927 13 histologic histologic JJ cord-022526-j9kg00qf 927 14 changes change NNS cord-022526-j9kg00qf 927 15 , , , cord-022526-j9kg00qf 927 16 13 13 CD cord-022526-j9kg00qf 927 17 and and CC cord-022526-j9kg00qf 927 18 interpretation interpretation NN cord-022526-j9kg00qf 927 19 is be VBZ cord-022526-j9kg00qf 927 20 clouded cloud VBN cord-022526-j9kg00qf 927 21 further far RBR cord-022526-j9kg00qf 927 22 by by IN cord-022526-j9kg00qf 927 23 findings finding NNS cord-022526-j9kg00qf 927 24 from from IN cord-022526-j9kg00qf 927 25 small small JJ cord-022526-j9kg00qf 927 26 intestinal intestinal JJ cord-022526-j9kg00qf 927 27 resection resection NN cord-022526-j9kg00qf 927 28 studies study NNS cord-022526-j9kg00qf 927 29 in in IN cord-022526-j9kg00qf 927 30 healthy healthy JJ cord-022526-j9kg00qf 927 31 ponies pony NNS cord-022526-j9kg00qf 927 32 . . . cord-022526-j9kg00qf 928 1 Nine nine CD cord-022526-j9kg00qf 928 2 ponies pony NNS cord-022526-j9kg00qf 928 3 with with IN cord-022526-j9kg00qf 928 4 70 70 CD cord-022526-j9kg00qf 928 5 % % NN cord-022526-j9kg00qf 928 6 distal distal JJ cord-022526-j9kg00qf 928 7 small small JJ cord-022526-j9kg00qf 928 8 intestinal intestinal JJ cord-022526-j9kg00qf 928 9 resection resection NN cord-022526-j9kg00qf 928 10 and and CC cord-022526-j9kg00qf 928 11 four four CD cord-022526-j9kg00qf 928 12 shamoperated shamoperated JJ cord-022526-j9kg00qf 928 13 controls control NNS cord-022526-j9kg00qf 928 14 were be VBD cord-022526-j9kg00qf 928 15 placed place VBN cord-022526-j9kg00qf 928 16 on on IN cord-022526-j9kg00qf 928 17 interval interval NN cord-022526-j9kg00qf 928 18 feeding feed VBG cord-022526-j9kg00qf 928 19 for for IN cord-022526-j9kg00qf 928 20 5 5 CD cord-022526-j9kg00qf 928 21 weeks week NNS cord-022526-j9kg00qf 928 22 and and CC cord-022526-j9kg00qf 928 23 then then RB cord-022526-j9kg00qf 928 24 turned turn VBD cord-022526-j9kg00qf 928 25 out out RP cord-022526-j9kg00qf 928 26 to to IN cord-022526-j9kg00qf 928 27 pasture pasture VB cord-022526-j9kg00qf 928 28 until until IN cord-022526-j9kg00qf 928 29 6 6 CD cord-022526-j9kg00qf 928 30 months month NNS cord-022526-j9kg00qf 928 31 after after IN cord-022526-j9kg00qf 928 32 surgery surgery NN cord-022526-j9kg00qf 928 33 . . . cord-022526-j9kg00qf 929 1 Grazing grazing NN cord-022526-j9kg00qf 929 2 was be VBD cord-022526-j9kg00qf 929 3 supplemented supplement VBN cord-022526-j9kg00qf 929 4 by by IN cord-022526-j9kg00qf 929 5 twice twice RB cord-022526-j9kg00qf 929 6 daily daily JJ cord-022526-j9kg00qf 929 7 ( ( -LRB- cord-022526-j9kg00qf 929 8 meal meal NN cord-022526-j9kg00qf 929 9 feeding feeding NN cord-022526-j9kg00qf 929 10 ) ) -RRB- cord-022526-j9kg00qf 929 11 concentrate concentrate NN cord-022526-j9kg00qf 929 12 rations ration NNS cord-022526-j9kg00qf 929 13 . . . cord-022526-j9kg00qf 930 1 All all DT cord-022526-j9kg00qf 930 2 ponies pony NNS cord-022526-j9kg00qf 930 3 gained gain VBD cord-022526-j9kg00qf 930 4 weight weight NN cord-022526-j9kg00qf 930 5 and and CC cord-022526-j9kg00qf 930 6 were be VBD cord-022526-j9kg00qf 930 7 clinically clinically RB cord-022526-j9kg00qf 930 8 normal normal JJ cord-022526-j9kg00qf 930 9 , , , cord-022526-j9kg00qf 930 10 and and CC cord-022526-j9kg00qf 930 11 none none NN cord-022526-j9kg00qf 930 12 developed develop VBD cord-022526-j9kg00qf 930 13 diarrhea diarrhea NN cord-022526-j9kg00qf 930 14 . . . cord-022526-j9kg00qf 931 1 However however RB cord-022526-j9kg00qf 931 2 , , , cord-022526-j9kg00qf 931 3 the the DT cord-022526-j9kg00qf 931 4 mean mean JJ cord-022526-j9kg00qf 931 5 peak peak JJ cord-022526-j9kg00qf 931 6 xylose xylose NN cord-022526-j9kg00qf 931 7 concentration concentration NN cord-022526-j9kg00qf 931 8 at at IN cord-022526-j9kg00qf 931 9 60 60 CD cord-022526-j9kg00qf 931 10 minutes minute NNS cord-022526-j9kg00qf 931 11 declined decline VBD cord-022526-j9kg00qf 931 12 progressively progressively RB cord-022526-j9kg00qf 931 13 ( ( -LRB- cord-022526-j9kg00qf 931 14 at at IN cord-022526-j9kg00qf 931 15 monthly monthly JJ cord-022526-j9kg00qf 931 16 intervals interval NNS cord-022526-j9kg00qf 931 17 ) ) -RRB- cord-022526-j9kg00qf 931 18 over over IN cord-022526-j9kg00qf 931 19 the the DT cord-022526-j9kg00qf 931 20 study study NN cord-022526-j9kg00qf 931 21 period period NN cord-022526-j9kg00qf 931 22 in in IN cord-022526-j9kg00qf 931 23 the the DT cord-022526-j9kg00qf 931 24 resection resection NN cord-022526-j9kg00qf 931 25 group group NN cord-022526-j9kg00qf 931 26 to to IN cord-022526-j9kg00qf 931 27 15 15 CD cord-022526-j9kg00qf 931 28 % % NN cord-022526-j9kg00qf 931 29 of of IN cord-022526-j9kg00qf 931 30 that that DT cord-022526-j9kg00qf 931 31 of of IN cord-022526-j9kg00qf 931 32 controls control NNS cord-022526-j9kg00qf 931 33 . . . cord-022526-j9kg00qf 932 1 Lack lack NN cord-022526-j9kg00qf 932 2 of of IN cord-022526-j9kg00qf 932 3 clinical clinical JJ cord-022526-j9kg00qf 932 4 malabsorption malabsorption NN cord-022526-j9kg00qf 932 5 was be VBD cord-022526-j9kg00qf 932 6 attributed attribute VBN cord-022526-j9kg00qf 932 7 to to IN cord-022526-j9kg00qf 932 8 adaptation adaptation NN cord-022526-j9kg00qf 932 9 of of IN cord-022526-j9kg00qf 932 10 the the DT cord-022526-j9kg00qf 932 11 residual residual JJ cord-022526-j9kg00qf 932 12 30 30 CD cord-022526-j9kg00qf 932 13 % % NN cord-022526-j9kg00qf 932 14 of of IN cord-022526-j9kg00qf 932 15 healthy healthy JJ cord-022526-j9kg00qf 932 16 small small JJ cord-022526-j9kg00qf 932 17 intestine intestine NN cord-022526-j9kg00qf 932 18 and and CC cord-022526-j9kg00qf 932 19 of of IN cord-022526-j9kg00qf 932 20 large large JJ cord-022526-j9kg00qf 932 21 intestinal intestinal JJ cord-022526-j9kg00qf 932 22 function function NN cord-022526-j9kg00qf 932 23 . . . cord-022526-j9kg00qf 933 1 14 14 CD cord-022526-j9kg00qf 933 2 Bacterial bacterial JJ cord-022526-j9kg00qf 933 3 overgrowth overgrowth NN cord-022526-j9kg00qf 933 4 in in IN cord-022526-j9kg00qf 933 5 the the DT cord-022526-j9kg00qf 933 6 small small JJ cord-022526-j9kg00qf 933 7 bowel bowel NN cord-022526-j9kg00qf 933 8 remnant remnant NN cord-022526-j9kg00qf 933 9 from from IN cord-022526-j9kg00qf 933 10 refluxed refluxed JJ cord-022526-j9kg00qf 933 11 cecal cecal JJ cord-022526-j9kg00qf 933 12 contents content NNS cord-022526-j9kg00qf 933 13 ( ( -LRB- cord-022526-j9kg00qf 933 14 resected resected JJ cord-022526-j9kg00qf 933 15 ponies pony NNS cord-022526-j9kg00qf 933 16 had have VBD cord-022526-j9kg00qf 933 17 ileocecal ileocecal JJ cord-022526-j9kg00qf 933 18 valve valve NN cord-022526-j9kg00qf 933 19 bypass bypass NN cord-022526-j9kg00qf 933 20 ) ) -RRB- cord-022526-j9kg00qf 933 21 may may MD cord-022526-j9kg00qf 933 22 have have VB cord-022526-j9kg00qf 933 23 contributed contribute VBN cord-022526-j9kg00qf 933 24 to to IN cord-022526-j9kg00qf 933 25 the the DT cord-022526-j9kg00qf 933 26 abnormal abnormal JJ cord-022526-j9kg00qf 933 27 xylose xylose NN cord-022526-j9kg00qf 933 28 assimilation assimilation NN cord-022526-j9kg00qf 933 29 . . . cord-022526-j9kg00qf 934 1 By by IN cord-022526-j9kg00qf 934 2 contrast contrast NN cord-022526-j9kg00qf 934 3 , , , cord-022526-j9kg00qf 934 4 xylose xylose NN cord-022526-j9kg00qf 934 5 absorption absorption NN cord-022526-j9kg00qf 934 6 decreased decrease VBD cord-022526-j9kg00qf 934 7 over over IN cord-022526-j9kg00qf 934 8 6 6 CD cord-022526-j9kg00qf 934 9 months month NNS cord-022526-j9kg00qf 934 10 , , , cord-022526-j9kg00qf 934 11 associated associate VBN cord-022526-j9kg00qf 934 12 with with IN cord-022526-j9kg00qf 934 13 substantial substantial JJ cord-022526-j9kg00qf 934 14 weight weight NN cord-022526-j9kg00qf 934 15 loss loss NN cord-022526-j9kg00qf 934 16 , , , cord-022526-j9kg00qf 934 17 lethargy lethargy NN cord-022526-j9kg00qf 934 18 , , , cord-022526-j9kg00qf 934 19 and and CC cord-022526-j9kg00qf 934 20 diarrhea diarrhea NN cord-022526-j9kg00qf 934 21 , , , cord-022526-j9kg00qf 934 22 in in IN cord-022526-j9kg00qf 934 23 an an DT cord-022526-j9kg00qf 934 24 earlier early JJR cord-022526-j9kg00qf 934 25 study study NN cord-022526-j9kg00qf 934 26 of of IN cord-022526-j9kg00qf 934 27 extensive extensive JJ cord-022526-j9kg00qf 934 28 ( ( -LRB- cord-022526-j9kg00qf 934 29 ≥60 ≥60 JJ cord-022526-j9kg00qf 934 30 % % NN cord-022526-j9kg00qf 934 31 ) ) -RRB- cord-022526-j9kg00qf 934 32 small small JJ cord-022526-j9kg00qf 934 33 intestinal intestinal JJ cord-022526-j9kg00qf 934 34 resection resection NN cord-022526-j9kg00qf 934 35 in in IN cord-022526-j9kg00qf 934 36 ponies pony NNS cord-022526-j9kg00qf 934 37 . . . cord-022526-j9kg00qf 935 1 15 15 CD cord-022526-j9kg00qf 936 1 An an DT cord-022526-j9kg00qf 936 2 important important JJ cord-022526-j9kg00qf 936 3 difference difference NN cord-022526-j9kg00qf 936 4 was be VBD cord-022526-j9kg00qf 936 5 the the DT cord-022526-j9kg00qf 936 6 feeding feeding NN cord-022526-j9kg00qf 936 7 pattern pattern NN cord-022526-j9kg00qf 936 8 ; ; : cord-022526-j9kg00qf 936 9 those those DT cord-022526-j9kg00qf 936 10 ponies pony NNS cord-022526-j9kg00qf 936 11 received receive VBD cord-022526-j9kg00qf 936 12 pelleted pellete VBN cord-022526-j9kg00qf 936 13 feed feed NN cord-022526-j9kg00qf 936 14 twice twice RB cord-022526-j9kg00qf 936 15 daily daily RB cord-022526-j9kg00qf 936 16 for for IN cord-022526-j9kg00qf 936 17 the the DT cord-022526-j9kg00qf 936 18 entire entire JJ cord-022526-j9kg00qf 936 19 6 6 CD cord-022526-j9kg00qf 936 20 month month NN cord-022526-j9kg00qf 936 21 follow follow NN cord-022526-j9kg00qf 936 22 - - HYPH cord-022526-j9kg00qf 936 23 up up NN cord-022526-j9kg00qf 936 24 period period NN cord-022526-j9kg00qf 936 25 . . . cord-022526-j9kg00qf 937 1 Consequently consequently RB cord-022526-j9kg00qf 937 2 , , , cord-022526-j9kg00qf 937 3 horses horse NNS cord-022526-j9kg00qf 937 4 with with IN cord-022526-j9kg00qf 937 5 suspected suspect VBN cord-022526-j9kg00qf 937 6 malabsorption malabsorption NN cord-022526-j9kg00qf 937 7 may may MD cord-022526-j9kg00qf 937 8 adapt adapt VB cord-022526-j9kg00qf 937 9 to to IN cord-022526-j9kg00qf 937 10 an an DT cord-022526-j9kg00qf 937 11 interval interval NN cord-022526-j9kg00qf 937 12 feeding feed VBG cord-022526-j9kg00qf 937 13 regimen regimen NN cord-022526-j9kg00qf 937 14 . . . cord-022526-j9kg00qf 938 1 The the DT cord-022526-j9kg00qf 938 2 critical critical JJ cord-022526-j9kg00qf 938 3 factor factor NN cord-022526-j9kg00qf 938 4 could could MD cord-022526-j9kg00qf 938 5 be be VB cord-022526-j9kg00qf 938 6 the the DT cord-022526-j9kg00qf 938 7 availability availability NN cord-022526-j9kg00qf 938 8 of of IN cord-022526-j9kg00qf 938 9 sufficient sufficient JJ cord-022526-j9kg00qf 938 10 unaffected unaffected JJ cord-022526-j9kg00qf 938 11 or or CC cord-022526-j9kg00qf 938 12 minimally minimally RB cord-022526-j9kg00qf 938 13 affected affected JJ cord-022526-j9kg00qf 938 14 small small JJ cord-022526-j9kg00qf 938 15 intestine intestine NN cord-022526-j9kg00qf 938 16 and and CC cord-022526-j9kg00qf 938 17 large large JJ cord-022526-j9kg00qf 938 18 intestinal intestinal JJ cord-022526-j9kg00qf 938 19 functional functional JJ cord-022526-j9kg00qf 938 20 capacity capacity NN cord-022526-j9kg00qf 938 21 . . . cord-022526-j9kg00qf 939 1 The the DT cord-022526-j9kg00qf 939 2 outcome outcome NN cord-022526-j9kg00qf 939 3 for for IN cord-022526-j9kg00qf 939 4 animals animal NNS cord-022526-j9kg00qf 939 5 with with IN cord-022526-j9kg00qf 939 6 small small JJ cord-022526-j9kg00qf 939 7 intestinal intestinal JJ cord-022526-j9kg00qf 939 8 disease disease NN cord-022526-j9kg00qf 939 9 and and CC cord-022526-j9kg00qf 939 10 some some DT cord-022526-j9kg00qf 939 11 unknown unknown JJ cord-022526-j9kg00qf 939 12 degree degree NN cord-022526-j9kg00qf 939 13 of of IN cord-022526-j9kg00qf 939 14 large large JJ cord-022526-j9kg00qf 939 15 intestinal intestinal JJ cord-022526-j9kg00qf 939 16 pathologic pathologic JJ cord-022526-j9kg00qf 939 17 dysfunction dysfunction NN cord-022526-j9kg00qf 939 18 may may MD cord-022526-j9kg00qf 939 19 be be VB cord-022526-j9kg00qf 939 20 less less RBR cord-022526-j9kg00qf 939 21 successful successful JJ cord-022526-j9kg00qf 939 22 than than IN cord-022526-j9kg00qf 939 23 shown show VBN cord-022526-j9kg00qf 939 24 in in IN cord-022526-j9kg00qf 939 25 the the DT cord-022526-j9kg00qf 939 26 experimental experimental JJ cord-022526-j9kg00qf 939 27 study study NN cord-022526-j9kg00qf 939 28 . . . cord-022526-j9kg00qf 940 1 Abnormal abnormal JJ cord-022526-j9kg00qf 940 2 xylose xylose NN cord-022526-j9kg00qf 940 3 absorption absorption NN cord-022526-j9kg00qf 940 4 reverted revert VBN cord-022526-j9kg00qf 940 5 to to IN cord-022526-j9kg00qf 940 6 normal normal JJ cord-022526-j9kg00qf 940 7 following follow VBG cord-022526-j9kg00qf 940 8 35 35 CD cord-022526-j9kg00qf 940 9 days day NNS cord-022526-j9kg00qf 940 10 of of IN cord-022526-j9kg00qf 940 11 corticosteroid corticosteroid NN cord-022526-j9kg00qf 940 12 therapy therapy NN cord-022526-j9kg00qf 940 13 in in IN cord-022526-j9kg00qf 940 14 an an DT cord-022526-j9kg00qf 940 15 adult adult NN cord-022526-j9kg00qf 940 16 Thoroughbred Thoroughbred NNP cord-022526-j9kg00qf 940 17 gelding gelding NN cord-022526-j9kg00qf 940 18 with with IN cord-022526-j9kg00qf 940 19 a a DT cord-022526-j9kg00qf 940 20 6-week 6-week CD cord-022526-j9kg00qf 940 21 history history NN cord-022526-j9kg00qf 940 22 of of IN cord-022526-j9kg00qf 940 23 weight weight NN cord-022526-j9kg00qf 940 24 loss loss NN cord-022526-j9kg00qf 940 25 and and CC cord-022526-j9kg00qf 940 26 diarrhea diarrhea NN cord-022526-j9kg00qf 940 27 for for IN cord-022526-j9kg00qf 940 28 3 3 CD cord-022526-j9kg00qf 940 29 weeks week NNS cord-022526-j9kg00qf 940 30 ; ; : cord-022526-j9kg00qf 940 31 peak peak JJ cord-022526-j9kg00qf 940 32 xylose xylose NN cord-022526-j9kg00qf 940 33 concentration concentration NN cord-022526-j9kg00qf 940 34 at at IN cord-022526-j9kg00qf 940 35 60 60 CD cord-022526-j9kg00qf 940 36 minutes minute NNS cord-022526-j9kg00qf 940 37 was be VBD cord-022526-j9kg00qf 940 38 within within IN cord-022526-j9kg00qf 940 39 normal normal JJ cord-022526-j9kg00qf 940 40 limits limit NNS cord-022526-j9kg00qf 940 41 and and CC cord-022526-j9kg00qf 940 42 the the DT cord-022526-j9kg00qf 940 43 horse horse NN cord-022526-j9kg00qf 940 44 had have VBD cord-022526-j9kg00qf 940 45 gained gain VBN cord-022526-j9kg00qf 940 46 weight weight NN cord-022526-j9kg00qf 940 47 . . . cord-022526-j9kg00qf 941 1 4 4 LS cord-022526-j9kg00qf 942 1 D d JJ cord-022526-j9kg00qf 942 2 - - HYPH cord-022526-j9kg00qf 942 3 xylose xylose NN cord-022526-j9kg00qf 942 4 absorption absorption NN cord-022526-j9kg00qf 942 5 was be VBD cord-022526-j9kg00qf 942 6 abnormal abnormal JJ cord-022526-j9kg00qf 942 7 in in IN cord-022526-j9kg00qf 942 8 an an DT cord-022526-j9kg00qf 942 9 adult adult NN cord-022526-j9kg00qf 942 10 Standardbred Standardbred NNP cord-022526-j9kg00qf 942 11 gelding gelding NN cord-022526-j9kg00qf 942 12 with with IN cord-022526-j9kg00qf 942 13 a a DT cord-022526-j9kg00qf 942 14 2-month 2-month JJ cord-022526-j9kg00qf 942 15 history history NN cord-022526-j9kg00qf 942 16 of of IN cord-022526-j9kg00qf 942 17 poor poor JJ cord-022526-j9kg00qf 942 18 performance performance NN cord-022526-j9kg00qf 942 19 , , , cord-022526-j9kg00qf 942 20 weight weight NN cord-022526-j9kg00qf 942 21 loss loss NN cord-022526-j9kg00qf 942 22 , , , cord-022526-j9kg00qf 942 23 intermittent intermittent JJ cord-022526-j9kg00qf 942 24 fever fever NN cord-022526-j9kg00qf 942 25 , , , cord-022526-j9kg00qf 942 26 mesenteric mesenteric JJ cord-022526-j9kg00qf 942 27 lymphadenopathy lymphadenopathy JJ cord-022526-j9kg00qf 942 28 , , , cord-022526-j9kg00qf 942 29 elevated elevated JJ cord-022526-j9kg00qf 942 30 fibrinogen fibrinogen NN cord-022526-j9kg00qf 942 31 , , , cord-022526-j9kg00qf 942 32 and and CC cord-022526-j9kg00qf 942 33 decreased decrease VBD cord-022526-j9kg00qf 942 34 albumin albumin NN cord-022526-j9kg00qf 942 35 and and CC cord-022526-j9kg00qf 942 36 globulin globulin NN cord-022526-j9kg00qf 942 37 levels level NNS cord-022526-j9kg00qf 942 38 . . . cord-022526-j9kg00qf 943 1 Multiple multiple JJ cord-022526-j9kg00qf 943 2 fullthickness fullthickness VBP cord-022526-j9kg00qf 943 3 small small JJ cord-022526-j9kg00qf 943 4 intestinal intestinal JJ cord-022526-j9kg00qf 943 5 biopsies biopsy NNS cord-022526-j9kg00qf 943 6 revealed reveal VBD cord-022526-j9kg00qf 943 7 evidence evidence NN cord-022526-j9kg00qf 943 8 of of IN cord-022526-j9kg00qf 943 9 granulomatous granulomatous JJ cord-022526-j9kg00qf 943 10 enteritis enteritis NN cord-022526-j9kg00qf 943 11 . . . cord-022526-j9kg00qf 944 1 The the DT cord-022526-j9kg00qf 944 2 horse horse NN cord-022526-j9kg00qf 944 3 received receive VBD cord-022526-j9kg00qf 944 4 antibiotics antibiotic NNS cord-022526-j9kg00qf 944 5 postoperatively postoperatively RB cord-022526-j9kg00qf 944 6 and and CC cord-022526-j9kg00qf 944 7 then then RB cord-022526-j9kg00qf 944 8 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 944 9 parenterally parenterally RB cord-022526-j9kg00qf 944 10 for for IN cord-022526-j9kg00qf 944 11 4 4 CD cord-022526-j9kg00qf 944 12 to to TO cord-022526-j9kg00qf 944 13 5 5 CD cord-022526-j9kg00qf 944 14 months month NNS cord-022526-j9kg00qf 944 15 . . . cord-022526-j9kg00qf 945 1 After after IN cord-022526-j9kg00qf 945 2 3 3 CD cord-022526-j9kg00qf 945 3 weeks week NNS cord-022526-j9kg00qf 945 4 , , , cord-022526-j9kg00qf 945 5 peak peak NN cord-022526-j9kg00qf 945 6 plasma plasma NN cord-022526-j9kg00qf 945 7 xylose xylose NN cord-022526-j9kg00qf 945 8 had have VBD cord-022526-j9kg00qf 945 9 increased increase VBN cord-022526-j9kg00qf 945 10 , , , cord-022526-j9kg00qf 945 11 although although IN cord-022526-j9kg00qf 945 12 absorption absorption NN cord-022526-j9kg00qf 945 13 was be VBD cord-022526-j9kg00qf 945 14 delayed delay VBN cord-022526-j9kg00qf 945 15 . . . cord-022526-j9kg00qf 946 1 Five five CD cord-022526-j9kg00qf 946 2 months month NNS cord-022526-j9kg00qf 946 3 after after IN cord-022526-j9kg00qf 946 4 cessation cessation NN cord-022526-j9kg00qf 946 5 of of IN cord-022526-j9kg00qf 946 6 corticosteroid corticosteroid NN cord-022526-j9kg00qf 946 7 therapy therapy NN cord-022526-j9kg00qf 946 8 , , , cord-022526-j9kg00qf 946 9 the the DT cord-022526-j9kg00qf 946 10 horse horse NN cord-022526-j9kg00qf 946 11 had have VBD cord-022526-j9kg00qf 946 12 regained regain VBN cord-022526-j9kg00qf 946 13 weight weight NN cord-022526-j9kg00qf 946 14 and and CC cord-022526-j9kg00qf 946 15 was be VBD cord-022526-j9kg00qf 946 16 bright bright JJ cord-022526-j9kg00qf 946 17 and and CC cord-022526-j9kg00qf 946 18 alert alert JJ cord-022526-j9kg00qf 946 19 , , , cord-022526-j9kg00qf 946 20 and and CC cord-022526-j9kg00qf 946 21 D d NN cord-022526-j9kg00qf 946 22 - - HYPH cord-022526-j9kg00qf 946 23 xylose xylose NN cord-022526-j9kg00qf 946 24 absorption absorption NN cord-022526-j9kg00qf 946 25 was be VBD cord-022526-j9kg00qf 946 26 normal normal JJ cord-022526-j9kg00qf 946 27 . . . cord-022526-j9kg00qf 947 1 16 16 CD cord-022526-j9kg00qf 948 1 Diagnostic diagnostic JJ cord-022526-j9kg00qf 948 2 predictions prediction NNS cord-022526-j9kg00qf 948 3 were be VBD cord-022526-j9kg00qf 948 4 made make VBN cord-022526-j9kg00qf 948 5 retrospectively retrospectively RB cord-022526-j9kg00qf 948 6 by by IN cord-022526-j9kg00qf 948 7 examining examine VBG cord-022526-j9kg00qf 948 8 D d NN cord-022526-j9kg00qf 948 9 - - HYPH cord-022526-j9kg00qf 948 10 xylose xylose NN cord-022526-j9kg00qf 948 11 absorption absorption NN cord-022526-j9kg00qf 948 12 in in IN cord-022526-j9kg00qf 948 13 horses horse NNS cord-022526-j9kg00qf 948 14 with with IN cord-022526-j9kg00qf 948 15 granulomatous granulomatous JJ cord-022526-j9kg00qf 948 16 enteritis enteritis NN cord-022526-j9kg00qf 948 17 compared compare VBN cord-022526-j9kg00qf 948 18 with with IN cord-022526-j9kg00qf 948 19 those those DT cord-022526-j9kg00qf 948 20 with with IN cord-022526-j9kg00qf 948 21 EG EG NNS cord-022526-j9kg00qf 948 22 . . . cord-022526-j9kg00qf 949 1 17 17 CD cord-022526-j9kg00qf 949 2 Peak Peak NNP cord-022526-j9kg00qf 949 3 xylose xylose NN cord-022526-j9kg00qf 949 4 concentrations concentration NNS cord-022526-j9kg00qf 949 5 were be VBD cord-022526-j9kg00qf 949 6 much much RB cord-022526-j9kg00qf 949 7 lower low JJR cord-022526-j9kg00qf 949 8 in in IN cord-022526-j9kg00qf 949 9 horses horse NNS cord-022526-j9kg00qf 949 10 with with IN cord-022526-j9kg00qf 949 11 granulomatous granulomatous JJ cord-022526-j9kg00qf 949 12 enteritis enteritis NN cord-022526-j9kg00qf 949 13 than than IN cord-022526-j9kg00qf 949 14 those those DT cord-022526-j9kg00qf 949 15 with with IN cord-022526-j9kg00qf 949 16 EG EG NNP cord-022526-j9kg00qf 949 17 , , , cord-022526-j9kg00qf 949 18 whereas whereas IN cord-022526-j9kg00qf 949 19 in in IN cord-022526-j9kg00qf 949 20 EG EG NNP cord-022526-j9kg00qf 949 21 the the DT cord-022526-j9kg00qf 949 22 absorption absorption NN cord-022526-j9kg00qf 949 23 curve curve NN cord-022526-j9kg00qf 949 24 shifted shift VBD cord-022526-j9kg00qf 949 25 to to IN cord-022526-j9kg00qf 949 26 the the DT cord-022526-j9kg00qf 949 27 right right NN cord-022526-j9kg00qf 949 28 with with IN cord-022526-j9kg00qf 949 29 the the DT cord-022526-j9kg00qf 949 30 peak peak NN cord-022526-j9kg00qf 949 31 occurring occur VBG cord-022526-j9kg00qf 949 32 at at IN cord-022526-j9kg00qf 949 33 240 240 CD cord-022526-j9kg00qf 949 34 minutes minute NNS cord-022526-j9kg00qf 949 35 . . . cord-022526-j9kg00qf 950 1 The the DT cord-022526-j9kg00qf 950 2 small small JJ cord-022526-j9kg00qf 950 3 intestine intestine NN cord-022526-j9kg00qf 950 4 is be VBZ cord-022526-j9kg00qf 950 5 affected affect VBN cord-022526-j9kg00qf 950 6 predominantly predominantly RB cord-022526-j9kg00qf 950 7 in in IN cord-022526-j9kg00qf 950 8 granulomatous granulomatous JJ cord-022526-j9kg00qf 950 9 enteritis enteritis NN cord-022526-j9kg00qf 950 10 with with IN cord-022526-j9kg00qf 950 11 extensive extensive JJ cord-022526-j9kg00qf 950 12 villous villous JJ cord-022526-j9kg00qf 950 13 atrophy atrophy NN cord-022526-j9kg00qf 950 14 and and CC cord-022526-j9kg00qf 950 15 more more RBR cord-022526-j9kg00qf 950 16 diffuse diffuse JJ cord-022526-j9kg00qf 950 17 lesions lesion NNS cord-022526-j9kg00qf 950 18 in in IN cord-022526-j9kg00qf 950 19 the the DT cord-022526-j9kg00qf 950 20 large large JJ cord-022526-j9kg00qf 950 21 intestine intestine NN cord-022526-j9kg00qf 950 22 , , , cord-022526-j9kg00qf 950 23 whereas whereas IN cord-022526-j9kg00qf 950 24 in in IN cord-022526-j9kg00qf 950 25 EG EG NNP cord-022526-j9kg00qf 950 26 ( ( -LRB- cord-022526-j9kg00qf 950 27 MEED MEED NNP cord-022526-j9kg00qf 950 28 ) ) -RRB- cord-022526-j9kg00qf 950 29 the the DT cord-022526-j9kg00qf 950 30 large large JJ cord-022526-j9kg00qf 950 31 intestine intestine NN cord-022526-j9kg00qf 950 32 is be VBZ cord-022526-j9kg00qf 950 33 more more RBR cord-022526-j9kg00qf 950 34 involved involved JJ cord-022526-j9kg00qf 950 35 . . . cord-022526-j9kg00qf 951 1 Hence hence RB cord-022526-j9kg00qf 951 2 , , , cord-022526-j9kg00qf 951 3 the the DT cord-022526-j9kg00qf 951 4 extent extent NN cord-022526-j9kg00qf 951 5 and and CC cord-022526-j9kg00qf 951 6 distribution distribution NN cord-022526-j9kg00qf 951 7 of of IN cord-022526-j9kg00qf 951 8 pathologic pathologic JJ cord-022526-j9kg00qf 951 9 changes change NNS cord-022526-j9kg00qf 951 10 in in IN cord-022526-j9kg00qf 951 11 the the DT cord-022526-j9kg00qf 951 12 small small JJ cord-022526-j9kg00qf 951 13 and and CC cord-022526-j9kg00qf 951 14 large large JJ cord-022526-j9kg00qf 951 15 intestines intestine NNS cord-022526-j9kg00qf 951 16 may may MD cord-022526-j9kg00qf 951 17 influence influence VB cord-022526-j9kg00qf 951 18 xylose xylose NN cord-022526-j9kg00qf 951 19 absorption absorption NN cord-022526-j9kg00qf 951 20 test test NN cord-022526-j9kg00qf 951 21 results result NNS cord-022526-j9kg00qf 951 22 . . . cord-022526-j9kg00qf 952 1 The the DT cord-022526-j9kg00qf 952 2 chronic chronic JJ cord-022526-j9kg00qf 952 3 wasting waste VBG cord-022526-j9kg00qf 952 4 horse horse NN cord-022526-j9kg00qf 952 5 with with IN cord-022526-j9kg00qf 952 6 suspected suspect VBN cord-022526-j9kg00qf 952 7 malabsorption malabsorption NN cord-022526-j9kg00qf 952 8 and and CC cord-022526-j9kg00qf 952 9 probable probable JJ cord-022526-j9kg00qf 952 10 enteric enteric JJ cord-022526-j9kg00qf 952 11 protein protein NN cord-022526-j9kg00qf 952 12 loss loss NN cord-022526-j9kg00qf 952 13 has have VBZ cord-022526-j9kg00qf 952 14 at at IN cord-022526-j9kg00qf 952 15 best well RBS cord-022526-j9kg00qf 952 16 a a DT cord-022526-j9kg00qf 952 17 guarded guard VBN cord-022526-j9kg00qf 952 18 to to IN cord-022526-j9kg00qf 952 19 poor poor JJ cord-022526-j9kg00qf 952 20 prognosis prognosis NN cord-022526-j9kg00qf 952 21 . . . cord-022526-j9kg00qf 953 1 Prognosis prognosis NN cord-022526-j9kg00qf 953 2 may may MD cord-022526-j9kg00qf 953 3 be be VB cord-022526-j9kg00qf 953 4 improved improve VBN cord-022526-j9kg00qf 953 5 through through IN cord-022526-j9kg00qf 953 6 early early JJ cord-022526-j9kg00qf 953 7 and and CC cord-022526-j9kg00qf 953 8 aggressive aggressive JJ cord-022526-j9kg00qf 953 9 investigation investigation NN cord-022526-j9kg00qf 953 10 to to TO cord-022526-j9kg00qf 953 11 achieve achieve VB cord-022526-j9kg00qf 953 12 a a DT cord-022526-j9kg00qf 953 13 diagnosis diagnosis NN cord-022526-j9kg00qf 953 14 , , , cord-022526-j9kg00qf 953 15 and and CC cord-022526-j9kg00qf 953 16 perhaps perhaps RB cord-022526-j9kg00qf 953 17 assess assess VB cord-022526-j9kg00qf 953 18 the the DT cord-022526-j9kg00qf 953 19 stage stage NN cord-022526-j9kg00qf 953 20 in in IN cord-022526-j9kg00qf 953 21 the the DT cord-022526-j9kg00qf 953 22 natural natural JJ cord-022526-j9kg00qf 953 23 progression progression NN cord-022526-j9kg00qf 953 24 of of IN cord-022526-j9kg00qf 953 25 the the DT cord-022526-j9kg00qf 953 26 disorder disorder NN cord-022526-j9kg00qf 953 27 . . . cord-022526-j9kg00qf 954 1 The the DT cord-022526-j9kg00qf 954 2 owner owner NN cord-022526-j9kg00qf 954 3 may may MD cord-022526-j9kg00qf 954 4 elect elect VB cord-022526-j9kg00qf 954 5 euthanasia euthanasia NN cord-022526-j9kg00qf 954 6 of of IN cord-022526-j9kg00qf 954 7 the the DT cord-022526-j9kg00qf 954 8 animal animal NN cord-022526-j9kg00qf 954 9 or or CC cord-022526-j9kg00qf 954 10 may may MD cord-022526-j9kg00qf 954 11 be be VB cord-022526-j9kg00qf 954 12 willing willing JJ cord-022526-j9kg00qf 954 13 to to TO cord-022526-j9kg00qf 954 14 determine determine VB cord-022526-j9kg00qf 954 15 whether whether IN cord-022526-j9kg00qf 954 16 the the DT cord-022526-j9kg00qf 954 17 condition condition NN cord-022526-j9kg00qf 954 18 can can MD cord-022526-j9kg00qf 954 19 be be VB cord-022526-j9kg00qf 954 20 improved improve VBN cord-022526-j9kg00qf 954 21 . . . cord-022526-j9kg00qf 955 1 In in IN cord-022526-j9kg00qf 955 2 the the DT cord-022526-j9kg00qf 955 3 short short JJ cord-022526-j9kg00qf 955 4 term term NN cord-022526-j9kg00qf 955 5 , , , cord-022526-j9kg00qf 955 6 intravenous intravenous JJ cord-022526-j9kg00qf 955 7 infusion infusion NN cord-022526-j9kg00qf 955 8 of of IN cord-022526-j9kg00qf 955 9 plasma plasma NN cord-022526-j9kg00qf 955 10 or or CC cord-022526-j9kg00qf 955 11 colloids colloid NNS cord-022526-j9kg00qf 955 12 , , , cord-022526-j9kg00qf 955 13 with with IN cord-022526-j9kg00qf 955 14 or or CC cord-022526-j9kg00qf 955 15 without without IN cord-022526-j9kg00qf 955 16 fluids fluid NNS cord-022526-j9kg00qf 955 17 and and CC cord-022526-j9kg00qf 955 18 electrolytes electrolyte NNS cord-022526-j9kg00qf 955 19 , , , cord-022526-j9kg00qf 955 20 may may MD cord-022526-j9kg00qf 955 21 be be VB cord-022526-j9kg00qf 955 22 necessary necessary JJ cord-022526-j9kg00qf 955 23 to to TO cord-022526-j9kg00qf 955 24 stabilize stabilize VB cord-022526-j9kg00qf 955 25 the the DT cord-022526-j9kg00qf 955 26 condition condition NN cord-022526-j9kg00qf 955 27 . . . cord-022526-j9kg00qf 956 1 Prognosis prognosis NN cord-022526-j9kg00qf 956 2 is be VBZ cord-022526-j9kg00qf 956 3 much much RB cord-022526-j9kg00qf 956 4 worse bad JJR cord-022526-j9kg00qf 956 5 for for IN cord-022526-j9kg00qf 956 6 the the DT cord-022526-j9kg00qf 956 7 horse horse NN cord-022526-j9kg00qf 956 8 that that WDT cord-022526-j9kg00qf 956 9 is be VBZ cord-022526-j9kg00qf 956 10 inappetent inappetent JJ cord-022526-j9kg00qf 956 11 . . . cord-022526-j9kg00qf 957 1 Prolonged prolonged JJ cord-022526-j9kg00qf 957 2 intensive intensive JJ cord-022526-j9kg00qf 957 3 total total JJ cord-022526-j9kg00qf 957 4 parenteral parenteral JJ cord-022526-j9kg00qf 957 5 nutrition nutrition NN cord-022526-j9kg00qf 957 6 and/or and/or CC cord-022526-j9kg00qf 957 7 oral oral JJ cord-022526-j9kg00qf 957 8 alimentation alimentation NN cord-022526-j9kg00qf 957 9 may may MD cord-022526-j9kg00qf 957 10 not not RB cord-022526-j9kg00qf 957 11 be be VB cord-022526-j9kg00qf 957 12 a a DT cord-022526-j9kg00qf 957 13 realistic realistic JJ cord-022526-j9kg00qf 957 14 course course NN cord-022526-j9kg00qf 957 15 of of IN cord-022526-j9kg00qf 957 16 action action NN cord-022526-j9kg00qf 957 17 . . . cord-022526-j9kg00qf 958 1 The the DT cord-022526-j9kg00qf 958 2 overall overall JJ cord-022526-j9kg00qf 958 3 therapeutic therapeutic JJ cord-022526-j9kg00qf 958 4 and and CC cord-022526-j9kg00qf 958 5 management management NN cord-022526-j9kg00qf 958 6 plan plan NN cord-022526-j9kg00qf 958 7 can can MD cord-022526-j9kg00qf 958 8 prove prove VB cord-022526-j9kg00qf 958 9 to to TO cord-022526-j9kg00qf 958 10 be be VB cord-022526-j9kg00qf 958 11 expensive expensive JJ cord-022526-j9kg00qf 958 12 . . . cord-022526-j9kg00qf 959 1 The the DT cord-022526-j9kg00qf 959 2 owner owner NN cord-022526-j9kg00qf 959 3 must must MD cord-022526-j9kg00qf 959 4 be be VB cord-022526-j9kg00qf 959 5 cognizant cognizant JJ cord-022526-j9kg00qf 959 6 from from IN cord-022526-j9kg00qf 959 7 the the DT cord-022526-j9kg00qf 959 8 start start NN cord-022526-j9kg00qf 959 9 that that IN cord-022526-j9kg00qf 959 10 the the DT cord-022526-j9kg00qf 959 11 outcome outcome NN cord-022526-j9kg00qf 959 12 may may MD cord-022526-j9kg00qf 959 13 not not RB cord-022526-j9kg00qf 959 14 be be VB cord-022526-j9kg00qf 959 15 altered alter VBN cord-022526-j9kg00qf 959 16 , , , cord-022526-j9kg00qf 959 17 even even RB cord-022526-j9kg00qf 959 18 after after IN cord-022526-j9kg00qf 959 19 protracted protract VBN cord-022526-j9kg00qf 959 20 therapy therapy NN cord-022526-j9kg00qf 959 21 . . . cord-022526-j9kg00qf 960 1 One one PRP cord-022526-j9kg00qf 960 2 can can MD cord-022526-j9kg00qf 960 3 not not RB cord-022526-j9kg00qf 960 4 make make VB cord-022526-j9kg00qf 960 5 predictions prediction NNS cord-022526-j9kg00qf 960 6 for for IN cord-022526-j9kg00qf 960 7 outcome outcome NN cord-022526-j9kg00qf 960 8 of of IN cord-022526-j9kg00qf 960 9 therapy therapy NN cord-022526-j9kg00qf 960 10 without without IN cord-022526-j9kg00qf 960 11 meaningful meaningful JJ cord-022526-j9kg00qf 960 12 data datum NNS cord-022526-j9kg00qf 960 13 because because IN cord-022526-j9kg00qf 960 14 only only RB cord-022526-j9kg00qf 960 15 a a DT cord-022526-j9kg00qf 960 16 few few JJ cord-022526-j9kg00qf 960 17 case case NN cord-022526-j9kg00qf 960 18 reports report NNS cord-022526-j9kg00qf 960 19 of of IN cord-022526-j9kg00qf 960 20 successful successful JJ cord-022526-j9kg00qf 960 21 responses response NNS cord-022526-j9kg00qf 960 22 with with IN cord-022526-j9kg00qf 960 23 long long JJ cord-022526-j9kg00qf 960 24 - - HYPH cord-022526-j9kg00qf 960 25 term term NN cord-022526-j9kg00qf 960 26 follow follow VB cord-022526-j9kg00qf 960 27 up up RP cord-022526-j9kg00qf 960 28 exist exist VBP cord-022526-j9kg00qf 960 29 . . . cord-022526-j9kg00qf 961 1 Some some DT cord-022526-j9kg00qf 961 2 level level NN cord-022526-j9kg00qf 961 3 of of IN cord-022526-j9kg00qf 961 4 digestive digestive JJ cord-022526-j9kg00qf 961 5 and and CC cord-022526-j9kg00qf 961 6 absorptive absorptive JJ cord-022526-j9kg00qf 961 7 capability capability NN cord-022526-j9kg00qf 961 8 remains remain VBZ cord-022526-j9kg00qf 961 9 in in IN cord-022526-j9kg00qf 961 10 the the DT cord-022526-j9kg00qf 961 11 diseased diseased JJ cord-022526-j9kg00qf 961 12 small small JJ cord-022526-j9kg00qf 961 13 intestine intestine NN cord-022526-j9kg00qf 961 14 . . . cord-022526-j9kg00qf 962 1 Interval interval NN cord-022526-j9kg00qf 962 2 feeding feeding NN cord-022526-j9kg00qf 962 3 of of IN cord-022526-j9kg00qf 962 4 small small JJ cord-022526-j9kg00qf 962 5 quantities quantity NNS cord-022526-j9kg00qf 962 6 of of IN cord-022526-j9kg00qf 962 7 food food NN cord-022526-j9kg00qf 962 8 may may MD cord-022526-j9kg00qf 962 9 be be VB cord-022526-j9kg00qf 962 10 beneficial beneficial JJ cord-022526-j9kg00qf 962 11 if if IN cord-022526-j9kg00qf 962 12 the the DT cord-022526-j9kg00qf 962 13 horse horse NN cord-022526-j9kg00qf 962 14 continues continue VBZ cord-022526-j9kg00qf 962 15 to to TO cord-022526-j9kg00qf 962 16 eat eat VB cord-022526-j9kg00qf 962 17 , , , cord-022526-j9kg00qf 962 18 and and CC cord-022526-j9kg00qf 962 19 particularly particularly RB cord-022526-j9kg00qf 962 20 for for IN cord-022526-j9kg00qf 962 21 animals animal NNS cord-022526-j9kg00qf 962 22 with with IN cord-022526-j9kg00qf 962 23 ravenous ravenous JJ cord-022526-j9kg00qf 962 24 appetites appetite NNS cord-022526-j9kg00qf 962 25 that that WDT cord-022526-j9kg00qf 962 26 seem seem VBP cord-022526-j9kg00qf 962 27 able able JJ cord-022526-j9kg00qf 962 28 to to TO cord-022526-j9kg00qf 962 29 maintain maintain VB cord-022526-j9kg00qf 962 30 their -PRON- PRP$ cord-022526-j9kg00qf 962 31 reduced reduce VBN cord-022526-j9kg00qf 962 32 state state NN cord-022526-j9kg00qf 962 33 of of IN cord-022526-j9kg00qf 962 34 body body NN cord-022526-j9kg00qf 962 35 condition condition NN cord-022526-j9kg00qf 962 36 without without IN cord-022526-j9kg00qf 962 37 further further JJ cord-022526-j9kg00qf 962 38 losses loss NNS cord-022526-j9kg00qf 962 39 . . . cord-022526-j9kg00qf 963 1 Diet Diet NNP cord-022526-j9kg00qf 963 2 should should MD cord-022526-j9kg00qf 963 3 include include VB cord-022526-j9kg00qf 963 4 feeds feed NNS cord-022526-j9kg00qf 963 5 with with IN cord-022526-j9kg00qf 963 6 a a DT cord-022526-j9kg00qf 963 7 high high JJ cord-022526-j9kg00qf 963 8 fiber fiber NN cord-022526-j9kg00qf 963 9 content content NN cord-022526-j9kg00qf 963 10 to to TO cord-022526-j9kg00qf 963 11 favor favor VB cord-022526-j9kg00qf 963 12 large large JJ cord-022526-j9kg00qf 963 13 intestinal intestinal JJ cord-022526-j9kg00qf 963 14 fermentation fermentation NN cord-022526-j9kg00qf 963 15 , , , cord-022526-j9kg00qf 963 16 including include VBG cord-022526-j9kg00qf 963 17 grass grass NN cord-022526-j9kg00qf 963 18 hay hay NN cord-022526-j9kg00qf 963 19 and and CC cord-022526-j9kg00qf 963 20 access access NN cord-022526-j9kg00qf 963 21 to to IN cord-022526-j9kg00qf 963 22 pasture pasture NN cord-022526-j9kg00qf 963 23 complemented complement VBN cord-022526-j9kg00qf 963 24 by by IN cord-022526-j9kg00qf 963 25 commercial commercial JJ cord-022526-j9kg00qf 963 26 high high JJ cord-022526-j9kg00qf 963 27 - - HYPH cord-022526-j9kg00qf 963 28 fiber fiber NN cord-022526-j9kg00qf 963 29 rations ration NNS cord-022526-j9kg00qf 963 30 based base VBN cord-022526-j9kg00qf 963 31 on on IN cord-022526-j9kg00qf 963 32 beet beet NN cord-022526-j9kg00qf 963 33 pulp pulp NN cord-022526-j9kg00qf 963 34 and and CC cord-022526-j9kg00qf 963 35 soybean soybean NN cord-022526-j9kg00qf 963 36 hulls hull NNS cord-022526-j9kg00qf 963 37 . . . cord-022526-j9kg00qf 964 1 Energy energy NN cord-022526-j9kg00qf 964 2 intake intake NN cord-022526-j9kg00qf 964 3 can can MD cord-022526-j9kg00qf 964 4 be be VB cord-022526-j9kg00qf 964 5 increased increase VBN cord-022526-j9kg00qf 964 6 through through IN cord-022526-j9kg00qf 964 7 feeding feed VBG cord-022526-j9kg00qf 964 8 high high JJ cord-022526-j9kg00qf 964 9 - - HYPH cord-022526-j9kg00qf 964 10 energy energy NN cord-022526-j9kg00qf 964 11 dense dense JJ cord-022526-j9kg00qf 964 12 fats fat NNS cord-022526-j9kg00qf 964 13 that that WDT cord-022526-j9kg00qf 964 14 provide provide VBP cord-022526-j9kg00qf 964 15 2.25 2.25 CD cord-022526-j9kg00qf 964 16 times time NNS cord-022526-j9kg00qf 964 17 more more JJR cord-022526-j9kg00qf 964 18 calories calorie NNS cord-022526-j9kg00qf 964 19 than than IN cord-022526-j9kg00qf 964 20 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 964 21 . . . cord-022526-j9kg00qf 965 1 Most most RBS cord-022526-j9kg00qf 965 2 affected affected JJ cord-022526-j9kg00qf 965 3 horses horse NNS cord-022526-j9kg00qf 965 4 should should MD cord-022526-j9kg00qf 965 5 tolerate tolerate VB cord-022526-j9kg00qf 965 6 high high JJ cord-022526-j9kg00qf 965 7 fat fat NN cord-022526-j9kg00qf 965 8 ( ( -LRB- cord-022526-j9kg00qf 965 9 5 5 CD cord-022526-j9kg00qf 965 10 % % NN cord-022526-j9kg00qf 965 11 to to TO cord-022526-j9kg00qf 965 12 10 10 CD cord-022526-j9kg00qf 965 13 % % NN cord-022526-j9kg00qf 965 14 ) ) -RRB- cord-022526-j9kg00qf 965 15 processed process VBN cord-022526-j9kg00qf 965 16 feeds feed NNS cord-022526-j9kg00qf 965 17 containing contain VBG cord-022526-j9kg00qf 965 18 vegetable vegetable NN cord-022526-j9kg00qf 965 19 oils oil NNS cord-022526-j9kg00qf 965 20 or or CC cord-022526-j9kg00qf 965 21 rice rice NN cord-022526-j9kg00qf 965 22 bran bran NN cord-022526-j9kg00qf 965 23 ( ( -LRB- cord-022526-j9kg00qf 965 24 up up IN cord-022526-j9kg00qf 965 25 to to TO cord-022526-j9kg00qf 965 26 20 20 CD cord-022526-j9kg00qf 965 27 % % NN cord-022526-j9kg00qf 965 28 of of IN cord-022526-j9kg00qf 965 29 the the DT cord-022526-j9kg00qf 965 30 concentrate concentrate NN cord-022526-j9kg00qf 965 31 mix mix NN cord-022526-j9kg00qf 965 32 , , , cord-022526-j9kg00qf 965 33 equivalent equivalent JJ cord-022526-j9kg00qf 965 34 to to IN cord-022526-j9kg00qf 965 35 8 8 CD cord-022526-j9kg00qf 965 36 % % NN cord-022526-j9kg00qf 965 37 vegetable vegetable NN cord-022526-j9kg00qf 965 38 oil oil NN cord-022526-j9kg00qf 965 39 ) ) -RRB- cord-022526-j9kg00qf 965 40 to to TO cord-022526-j9kg00qf 965 41 achieve achieve VB cord-022526-j9kg00qf 965 42 the the DT cord-022526-j9kg00qf 965 43 higher high JJR cord-022526-j9kg00qf 965 44 - - HYPH cord-022526-j9kg00qf 965 45 fat fat NN cord-022526-j9kg00qf 965 46 composition composition NN cord-022526-j9kg00qf 965 47 . . . cord-022526-j9kg00qf 966 1 Changeover changeover NN cord-022526-j9kg00qf 966 2 to to IN cord-022526-j9kg00qf 966 3 a a DT cord-022526-j9kg00qf 966 4 higher high JJR cord-022526-j9kg00qf 966 5 - - HYPH cord-022526-j9kg00qf 966 6 fat fat NN cord-022526-j9kg00qf 966 7 concentrate concentrate NN cord-022526-j9kg00qf 966 8 should should MD cord-022526-j9kg00qf 966 9 be be VB cord-022526-j9kg00qf 966 10 gradual gradual JJ cord-022526-j9kg00qf 966 11 . . . cord-022526-j9kg00qf 967 1 Even even RB cord-022526-j9kg00qf 967 2 in in IN cord-022526-j9kg00qf 967 3 healthy healthy JJ cord-022526-j9kg00qf 967 4 animals animal NNS cord-022526-j9kg00qf 967 5 that that WDT cord-022526-j9kg00qf 967 6 can can MD cord-022526-j9kg00qf 967 7 eat eat VB cord-022526-j9kg00qf 967 8 up up IN cord-022526-j9kg00qf 967 9 to to TO cord-022526-j9kg00qf 967 10 20 20 CD cord-022526-j9kg00qf 967 11 % % NN cord-022526-j9kg00qf 967 12 added add VBN cord-022526-j9kg00qf 967 13 fat fat JJ cord-022526-j9kg00qf 967 14 , , , cord-022526-j9kg00qf 967 15 appetite appetite NN cord-022526-j9kg00qf 967 16 may may MD cord-022526-j9kg00qf 967 17 decrease decrease VB cord-022526-j9kg00qf 967 18 as as IN cord-022526-j9kg00qf 967 19 the the DT cord-022526-j9kg00qf 967 20 percentage percentage NN cord-022526-j9kg00qf 967 21 increases increase NNS cord-022526-j9kg00qf 967 22 , , , cord-022526-j9kg00qf 967 23 and and CC cord-022526-j9kg00qf 967 24 fecal fecal JJ cord-022526-j9kg00qf 967 25 consistency consistency NN cord-022526-j9kg00qf 967 26 may may MD cord-022526-j9kg00qf 967 27 change change VB cord-022526-j9kg00qf 967 28 . . . cord-022526-j9kg00qf 968 1 Clearly clearly RB cord-022526-j9kg00qf 968 2 , , , cord-022526-j9kg00qf 968 3 the the DT cord-022526-j9kg00qf 968 4 objective objective NN cord-022526-j9kg00qf 968 5 for for IN cord-022526-j9kg00qf 968 6 the the DT cord-022526-j9kg00qf 968 7 horse horse NN cord-022526-j9kg00qf 968 8 with with IN cord-022526-j9kg00qf 968 9 suspected suspect VBN cord-022526-j9kg00qf 968 10 malabsorption malabsorption NN cord-022526-j9kg00qf 968 11 is be VBZ cord-022526-j9kg00qf 968 12 to to TO cord-022526-j9kg00qf 968 13 sustain sustain VB cord-022526-j9kg00qf 968 14 , , , cord-022526-j9kg00qf 968 15 and and CC cord-022526-j9kg00qf 968 16 preferably preferably RB cord-022526-j9kg00qf 968 17 increase increase VB cord-022526-j9kg00qf 968 18 , , , cord-022526-j9kg00qf 968 19 dietary dietary JJ cord-022526-j9kg00qf 968 20 intake intake NN cord-022526-j9kg00qf 968 21 , , , cord-022526-j9kg00qf 968 22 value value NN cord-022526-j9kg00qf 968 23 , , , cord-022526-j9kg00qf 968 24 and and CC cord-022526-j9kg00qf 968 25 efficiency efficiency NN cord-022526-j9kg00qf 968 26 . . . cord-022526-j9kg00qf 969 1 The the DT cord-022526-j9kg00qf 969 2 owner owner NN cord-022526-j9kg00qf 969 3 of of IN cord-022526-j9kg00qf 969 4 an an DT cord-022526-j9kg00qf 969 5 affected affected JJ cord-022526-j9kg00qf 969 6 horse horse NN cord-022526-j9kg00qf 969 7 must must MD cord-022526-j9kg00qf 969 8 be be VB cord-022526-j9kg00qf 969 9 prepared prepared JJ cord-022526-j9kg00qf 969 10 to to TO cord-022526-j9kg00qf 969 11 experiment experiment VB cord-022526-j9kg00qf 969 12 with with IN cord-022526-j9kg00qf 969 13 feeds feed NNS cord-022526-j9kg00qf 969 14 , , , cord-022526-j9kg00qf 969 15 must must MD cord-022526-j9kg00qf 969 16 be be VB cord-022526-j9kg00qf 969 17 patient patient JJ cord-022526-j9kg00qf 969 18 , , , cord-022526-j9kg00qf 969 19 and and CC cord-022526-j9kg00qf 969 20 must must MD cord-022526-j9kg00qf 969 21 keep keep VB cord-022526-j9kg00qf 969 22 records record NNS cord-022526-j9kg00qf 969 23 . . . cord-022526-j9kg00qf 970 1 No no DT cord-022526-j9kg00qf 970 2 standard standard JJ cord-022526-j9kg00qf 970 3 procedure procedure NN cord-022526-j9kg00qf 970 4 exists exist VBZ cord-022526-j9kg00qf 970 5 . . . cord-022526-j9kg00qf 971 1 Exposure exposure NN cord-022526-j9kg00qf 971 2 to to IN cord-022526-j9kg00qf 971 3 a a DT cord-022526-j9kg00qf 971 4 feed feed NN cord-022526-j9kg00qf 971 5 component component NN cord-022526-j9kg00qf 971 6 may may MD cord-022526-j9kg00qf 971 7 contribute contribute VB cord-022526-j9kg00qf 971 8 to to IN cord-022526-j9kg00qf 971 9 the the DT cord-022526-j9kg00qf 971 10 problem problem NN cord-022526-j9kg00qf 971 11 as as IN cord-022526-j9kg00qf 971 12 an an DT cord-022526-j9kg00qf 971 13 allergen allergen NN cord-022526-j9kg00qf 971 14 eliciting elicit VBG cord-022526-j9kg00qf 971 15 a a DT cord-022526-j9kg00qf 971 16 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 971 17 reaction reaction NN cord-022526-j9kg00qf 971 18 . . . cord-022526-j9kg00qf 972 1 Identifying identify VBG cord-022526-j9kg00qf 972 2 the the DT cord-022526-j9kg00qf 972 3 potential potential JJ cord-022526-j9kg00qf 972 4 allergen allergen NN cord-022526-j9kg00qf 972 5 through through IN cord-022526-j9kg00qf 972 6 immunologic immunologic JJ cord-022526-j9kg00qf 972 7 testing testing NN cord-022526-j9kg00qf 972 8 or or CC cord-022526-j9kg00qf 972 9 by by IN cord-022526-j9kg00qf 972 10 stepwise stepwise JJ cord-022526-j9kg00qf 972 11 removal removal NN cord-022526-j9kg00qf 972 12 and and CC cord-022526-j9kg00qf 972 13 outcome outcome NN cord-022526-j9kg00qf 972 14 assessment assessment NN cord-022526-j9kg00qf 972 15 over over IN cord-022526-j9kg00qf 972 16 a a DT cord-022526-j9kg00qf 972 17 longer long JJR cord-022526-j9kg00qf 972 18 period period NN cord-022526-j9kg00qf 972 19 may may MD cord-022526-j9kg00qf 972 20 be be VB cord-022526-j9kg00qf 972 21 difficult difficult JJ cord-022526-j9kg00qf 972 22 . . . cord-022526-j9kg00qf 973 1 The the DT cord-022526-j9kg00qf 973 2 clinician clinician NN cord-022526-j9kg00qf 973 3 should should MD cord-022526-j9kg00qf 973 4 give give VB cord-022526-j9kg00qf 973 5 immunosuppressive immunosuppressive JJ cord-022526-j9kg00qf 973 6 drugs drug NNS cord-022526-j9kg00qf 973 7 early early RB cord-022526-j9kg00qf 973 8 in in IN cord-022526-j9kg00qf 973 9 the the DT cord-022526-j9kg00qf 973 10 process process NN cord-022526-j9kg00qf 973 11 . . . cord-022526-j9kg00qf 974 1 Immunosuppressive immunosuppressive JJ cord-022526-j9kg00qf 974 2 agents agent NNS cord-022526-j9kg00qf 974 3 have have VBP cord-022526-j9kg00qf 974 4 produced produce VBN cord-022526-j9kg00qf 974 5 the the DT cord-022526-j9kg00qf 974 6 most most RBS cord-022526-j9kg00qf 974 7 promising promising JJ cord-022526-j9kg00qf 974 8 responses response NNS cord-022526-j9kg00qf 974 9 to to TO cord-022526-j9kg00qf 974 10 ameliorate ameliorate VB cord-022526-j9kg00qf 974 11 the the DT cord-022526-j9kg00qf 974 12 effects effect NNS cord-022526-j9kg00qf 974 13 of of IN cord-022526-j9kg00qf 974 14 conditions condition NNS cord-022526-j9kg00qf 974 15 associated associate VBN cord-022526-j9kg00qf 974 16 with with IN cord-022526-j9kg00qf 974 17 malabsorption malabsorption NN cord-022526-j9kg00qf 974 18 , , , cord-022526-j9kg00qf 974 19 particularly particularly RB cord-022526-j9kg00qf 974 20 CIBD CIBD NNP cord-022526-j9kg00qf 974 21 . . . cord-022526-j9kg00qf 975 1 Short short JJ cord-022526-j9kg00qf 975 2 - - HYPH cord-022526-j9kg00qf 975 3 duration duration NN cord-022526-j9kg00qf 975 4 , , , cord-022526-j9kg00qf 975 5 and and CC cord-022526-j9kg00qf 975 6 in in IN cord-022526-j9kg00qf 975 7 some some DT cord-022526-j9kg00qf 975 8 cases case NNS cord-022526-j9kg00qf 975 9 more more RBR cord-022526-j9kg00qf 975 10 prolonged prolonged JJ cord-022526-j9kg00qf 975 11 and and CC cord-022526-j9kg00qf 975 12 sustained sustain VBN cord-022526-j9kg00qf 975 13 , , , cord-022526-j9kg00qf 975 14 improvements improvement NNS cord-022526-j9kg00qf 975 15 in in IN cord-022526-j9kg00qf 975 16 body body NN cord-022526-j9kg00qf 975 17 condition condition NN cord-022526-j9kg00qf 975 18 , , , cord-022526-j9kg00qf 975 19 weight weight NN cord-022526-j9kg00qf 975 20 gain gain NN cord-022526-j9kg00qf 975 21 , , , cord-022526-j9kg00qf 975 22 demeanor demeanor NN cord-022526-j9kg00qf 975 23 , , , cord-022526-j9kg00qf 975 24 energy energy NN cord-022526-j9kg00qf 975 25 and and CC cord-022526-j9kg00qf 975 26 activity activity NN cord-022526-j9kg00qf 975 27 levels level NNS cord-022526-j9kg00qf 975 28 have have VBP cord-022526-j9kg00qf 975 29 occurred occur VBN cord-022526-j9kg00qf 975 30 following follow VBG cord-022526-j9kg00qf 975 31 corticosteroid corticosteroid NNP cord-022526-j9kg00qf 975 32 administration administration NN cord-022526-j9kg00qf 975 33 . . . cord-022526-j9kg00qf 976 1 One one PRP cord-022526-j9kg00qf 976 2 should should MD cord-022526-j9kg00qf 976 3 start start VB cord-022526-j9kg00qf 976 4 treatment treatment NN cord-022526-j9kg00qf 976 5 as as RB cord-022526-j9kg00qf 976 6 early early RB cord-022526-j9kg00qf 976 7 as as IN cord-022526-j9kg00qf 976 8 possible possible JJ cord-022526-j9kg00qf 976 9 . . . cord-022526-j9kg00qf 977 1 One one PRP cord-022526-j9kg00qf 977 2 should should MD cord-022526-j9kg00qf 977 3 follow follow VB cord-022526-j9kg00qf 977 4 initial initial JJ cord-022526-j9kg00qf 977 5 parenteral parenteral JJ cord-022526-j9kg00qf 977 6 ( ( -LRB- cord-022526-j9kg00qf 977 7 intramuscular intramuscular JJ cord-022526-j9kg00qf 977 8 or or CC cord-022526-j9kg00qf 977 9 intravenous intravenous JJ cord-022526-j9kg00qf 977 10 ) ) -RRB- cord-022526-j9kg00qf 977 11 loading load VBG cord-022526-j9kg00qf 977 12 doses dose NNS cord-022526-j9kg00qf 977 13 of of IN cord-022526-j9kg00qf 977 14 dexamethasone dexamethasone NN cord-022526-j9kg00qf 977 15 ( ( -LRB- cord-022526-j9kg00qf 977 16 sodium sodium NN cord-022526-j9kg00qf 977 17 phosphate phosphate NN cord-022526-j9kg00qf 977 18 ) ) -RRB- cord-022526-j9kg00qf 977 19 with with IN cord-022526-j9kg00qf 977 20 a a DT cord-022526-j9kg00qf 977 21 series series NN cord-022526-j9kg00qf 977 22 of of IN cord-022526-j9kg00qf 977 23 depot depot NN cord-022526-j9kg00qf 977 24 injections injection NNS cord-022526-j9kg00qf 977 25 , , , cord-022526-j9kg00qf 977 26 or or CC cord-022526-j9kg00qf 977 27 orally orally RB cord-022526-j9kg00qf 977 28 administered administer VBD cord-022526-j9kg00qf 977 29 prednisolone prednisolone NN cord-022526-j9kg00qf 977 30 or or CC cord-022526-j9kg00qf 977 31 prednisone prednisone NNP cord-022526-j9kg00qf 977 32 , , , cord-022526-j9kg00qf 977 33 on on IN cord-022526-j9kg00qf 977 34 a a DT cord-022526-j9kg00qf 977 35 tapered tapered JJ cord-022526-j9kg00qf 977 36 dose dose NN cord-022526-j9kg00qf 977 37 protocol protocol NN cord-022526-j9kg00qf 977 38 over over IN cord-022526-j9kg00qf 977 39 a a DT cord-022526-j9kg00qf 977 40 period period NN cord-022526-j9kg00qf 977 41 of of IN cord-022526-j9kg00qf 977 42 months month NNS cord-022526-j9kg00qf 977 43 . . . cord-022526-j9kg00qf 978 1 Interval interval NN cord-022526-j9kg00qf 978 2 low low JJ cord-022526-j9kg00qf 978 3 - - HYPH cord-022526-j9kg00qf 978 4 dose dose NN cord-022526-j9kg00qf 978 5 therapy therapy NN cord-022526-j9kg00qf 978 6 may may MD cord-022526-j9kg00qf 978 7 be be VB cord-022526-j9kg00qf 978 8 necessary necessary JJ cord-022526-j9kg00qf 978 9 if if IN cord-022526-j9kg00qf 978 10 clinical clinical JJ cord-022526-j9kg00qf 978 11 signs sign NNS cord-022526-j9kg00qf 978 12 return return VBP cord-022526-j9kg00qf 978 13 after after IN cord-022526-j9kg00qf 978 14 treatment treatment NN cord-022526-j9kg00qf 978 15 ends end NNS cord-022526-j9kg00qf 978 16 . . . cord-022526-j9kg00qf 979 1 One one CD cord-022526-j9kg00qf 979 2 uses use VBZ cord-022526-j9kg00qf 979 3 the the DT cord-022526-j9kg00qf 979 4 lowest low JJS cord-022526-j9kg00qf 979 5 dose dose NN cord-022526-j9kg00qf 979 6 to to TO cord-022526-j9kg00qf 979 7 control control VB cord-022526-j9kg00qf 979 8 the the DT cord-022526-j9kg00qf 979 9 clinical clinical JJ cord-022526-j9kg00qf 979 10 signs sign NNS cord-022526-j9kg00qf 979 11 for for IN cord-022526-j9kg00qf 979 12 alternate alternate JJ cord-022526-j9kg00qf 979 13 - - HYPH cord-022526-j9kg00qf 979 14 day day NN cord-022526-j9kg00qf 979 15 therapy therapy NN cord-022526-j9kg00qf 979 16 . . . cord-022526-j9kg00qf 980 1 Clinical clinical JJ cord-022526-j9kg00qf 980 2 benefits benefit NNS cord-022526-j9kg00qf 980 3 far far RB cord-022526-j9kg00qf 980 4 outweigh outweigh VBP cord-022526-j9kg00qf 980 5 concerns concern NNS cord-022526-j9kg00qf 980 6 over over IN cord-022526-j9kg00qf 980 7 potential potential JJ cord-022526-j9kg00qf 980 8 adverse adverse JJ cord-022526-j9kg00qf 980 9 effects effect NNS cord-022526-j9kg00qf 980 10 . . . cord-022526-j9kg00qf 981 1 Chemotherapeutic chemotherapeutic JJ cord-022526-j9kg00qf 981 2 agents agent NNS cord-022526-j9kg00qf 981 3 such such JJ cord-022526-j9kg00qf 981 4 as as IN cord-022526-j9kg00qf 981 5 vincristine vincristine NN cord-022526-j9kg00qf 981 6 , , , cord-022526-j9kg00qf 981 7 cytosine cytosine NN cord-022526-j9kg00qf 981 8 , , , cord-022526-j9kg00qf 981 9 cyclophosphamide cyclophosphamide RB cord-022526-j9kg00qf 981 10 , , , cord-022526-j9kg00qf 981 11 and and CC cord-022526-j9kg00qf 981 12 hydroxyurea hydroxyurea NNP cord-022526-j9kg00qf 981 13 have have VBP cord-022526-j9kg00qf 981 14 been be VBN cord-022526-j9kg00qf 981 15 tried try VBN cord-022526-j9kg00qf 981 16 in in IN cord-022526-j9kg00qf 981 17 a a DT cord-022526-j9kg00qf 981 18 few few JJ cord-022526-j9kg00qf 981 19 cases case NNS cord-022526-j9kg00qf 981 20 of of IN cord-022526-j9kg00qf 981 21 CIBD CIBD NNP cord-022526-j9kg00qf 981 22 or or CC cord-022526-j9kg00qf 981 23 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 981 24 with with IN cord-022526-j9kg00qf 981 25 no no DT cord-022526-j9kg00qf 981 26 apparent apparent JJ cord-022526-j9kg00qf 981 27 success success NN cord-022526-j9kg00qf 981 28 , , , cord-022526-j9kg00qf 981 29 probably probably RB cord-022526-j9kg00qf 981 30 related relate VBN cord-022526-j9kg00qf 981 31 to to IN cord-022526-j9kg00qf 981 32 the the DT cord-022526-j9kg00qf 981 33 advanced advanced JJ cord-022526-j9kg00qf 981 34 stage stage NN cord-022526-j9kg00qf 981 35 of of IN cord-022526-j9kg00qf 981 36 the the DT cord-022526-j9kg00qf 981 37 disease disease NN cord-022526-j9kg00qf 981 38 when when WRB cord-022526-j9kg00qf 981 39 treatment treatment NN cord-022526-j9kg00qf 981 40 was be VBD cord-022526-j9kg00qf 981 41 initiated initiate VBN cord-022526-j9kg00qf 981 42 and and CC cord-022526-j9kg00qf 981 43 the the DT cord-022526-j9kg00qf 981 44 dose dose NN cord-022526-j9kg00qf 981 45 selected select VBN cord-022526-j9kg00qf 981 46 . . . cord-022526-j9kg00qf 982 1 Resection resection NN cord-022526-j9kg00qf 982 2 of of IN cord-022526-j9kg00qf 982 3 a a DT cord-022526-j9kg00qf 982 4 segment segment NN cord-022526-j9kg00qf 982 5 of of IN cord-022526-j9kg00qf 982 6 intestine intestine NN cord-022526-j9kg00qf 982 7 that that WDT cord-022526-j9kg00qf 982 8 is be VBZ cord-022526-j9kg00qf 982 9 edematous edematous JJ cord-022526-j9kg00qf 982 10 , , , cord-022526-j9kg00qf 982 11 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 982 12 , , , cord-022526-j9kg00qf 982 13 or or CC cord-022526-j9kg00qf 982 14 constricted constricted JJ cord-022526-j9kg00qf 982 15 is be VBZ cord-022526-j9kg00qf 982 16 an an DT cord-022526-j9kg00qf 982 17 option option NN cord-022526-j9kg00qf 982 18 in in IN cord-022526-j9kg00qf 982 19 localized localized JJ cord-022526-j9kg00qf 982 20 forms form NNS cord-022526-j9kg00qf 982 21 of of IN cord-022526-j9kg00qf 982 22 CIBD CIBD NNP cord-022526-j9kg00qf 982 23 , , , cord-022526-j9kg00qf 982 24 18 18 CD cord-022526-j9kg00qf 982 25 , , , cord-022526-j9kg00qf 982 26 19 19 CD cord-022526-j9kg00qf 982 27 particularly particularly RB cord-022526-j9kg00qf 982 28 if if IN cord-022526-j9kg00qf 982 29 gross gross JJ cord-022526-j9kg00qf 982 30 changes change NNS cord-022526-j9kg00qf 982 31 are be VBP cord-022526-j9kg00qf 982 32 not not RB cord-022526-j9kg00qf 982 33 discernible discernible JJ cord-022526-j9kg00qf 982 34 in in IN cord-022526-j9kg00qf 982 35 adjacent adjacent JJ cord-022526-j9kg00qf 982 36 or or CC cord-022526-j9kg00qf 982 37 distant distant JJ cord-022526-j9kg00qf 982 38 parts part NNS cord-022526-j9kg00qf 982 39 of of IN cord-022526-j9kg00qf 982 40 the the DT cord-022526-j9kg00qf 982 41 intestinal intestinal JJ cord-022526-j9kg00qf 982 42 tract tract NN cord-022526-j9kg00qf 982 43 , , , cord-022526-j9kg00qf 982 44 that that RB cord-022526-j9kg00qf 982 45 is is RB cord-022526-j9kg00qf 982 46 , , , cord-022526-j9kg00qf 982 47 malabsorption malabsorption NN cord-022526-j9kg00qf 982 48 is be VBZ cord-022526-j9kg00qf 982 49 not not RB cord-022526-j9kg00qf 982 50 a a DT cord-022526-j9kg00qf 982 51 feature feature NN cord-022526-j9kg00qf 982 52 . . . cord-022526-j9kg00qf 983 1 Long long JJ cord-022526-j9kg00qf 983 2 - - HYPH cord-022526-j9kg00qf 983 3 term term NN cord-022526-j9kg00qf 983 4 outcome outcome NN cord-022526-j9kg00qf 983 5 has have VBZ cord-022526-j9kg00qf 983 6 been be VBN cord-022526-j9kg00qf 983 7 favorable favorable JJ cord-022526-j9kg00qf 983 8 . . . cord-022526-j9kg00qf 984 1 Removal removal NN cord-022526-j9kg00qf 984 2 of of IN cord-022526-j9kg00qf 984 3 a a DT cord-022526-j9kg00qf 984 4 substantial substantial JJ cord-022526-j9kg00qf 984 5 proportion proportion NN cord-022526-j9kg00qf 984 6 of of IN cord-022526-j9kg00qf 984 7 the the DT cord-022526-j9kg00qf 984 8 diseased diseased JJ cord-022526-j9kg00qf 984 9 small small JJ cord-022526-j9kg00qf 984 10 intestine intestine NN cord-022526-j9kg00qf 984 11 may may MD cord-022526-j9kg00qf 984 12 be be VB cord-022526-j9kg00qf 984 13 indicated indicate VBN cord-022526-j9kg00qf 984 14 in in IN cord-022526-j9kg00qf 984 15 a a DT cord-022526-j9kg00qf 984 16 horse horse NN cord-022526-j9kg00qf 984 17 with with IN cord-022526-j9kg00qf 984 18 malabsorption malabsorption NN cord-022526-j9kg00qf 984 19 , , , cord-022526-j9kg00qf 984 20 considering consider VBG cord-022526-j9kg00qf 984 21 that that IN cord-022526-j9kg00qf 984 22 resection resection NN cord-022526-j9kg00qf 984 23 of of IN cord-022526-j9kg00qf 984 24 70 70 CD cord-022526-j9kg00qf 984 25 % % NN cord-022526-j9kg00qf 984 26 distal distal JJ cord-022526-j9kg00qf 984 27 small small JJ cord-022526-j9kg00qf 984 28 intestine intestine NN cord-022526-j9kg00qf 984 29 was be VBD cord-022526-j9kg00qf 984 30 performed perform VBN cord-022526-j9kg00qf 984 31 in in IN cord-022526-j9kg00qf 984 32 healthy healthy JJ cord-022526-j9kg00qf 984 33 animals animal NNS cord-022526-j9kg00qf 984 34 without without IN cord-022526-j9kg00qf 984 35 inducing induce VBG cord-022526-j9kg00qf 984 36 adverse adverse JJ cord-022526-j9kg00qf 984 37 effects effect NNS cord-022526-j9kg00qf 984 38 . . . cord-022526-j9kg00qf 985 1 However however RB cord-022526-j9kg00qf 985 2 , , , cord-022526-j9kg00qf 985 3 because because IN cord-022526-j9kg00qf 985 4 pathologic pathologic JJ cord-022526-j9kg00qf 985 5 changes change NNS cord-022526-j9kg00qf 985 6 may may MD cord-022526-j9kg00qf 985 7 exist exist VB cord-022526-j9kg00qf 985 8 in in IN cord-022526-j9kg00qf 985 9 normalappearing normalappeare VBG cord-022526-j9kg00qf 985 10 small small JJ cord-022526-j9kg00qf 985 11 or or CC cord-022526-j9kg00qf 985 12 large large JJ cord-022526-j9kg00qf 985 13 intestine intestine NN cord-022526-j9kg00qf 985 14 that that WDT cord-022526-j9kg00qf 985 15 is be VBZ cord-022526-j9kg00qf 985 16 not not RB cord-022526-j9kg00qf 985 17 resected resect VBN cord-022526-j9kg00qf 985 18 or or CC cord-022526-j9kg00qf 985 19 biopsied biopsie VBN cord-022526-j9kg00qf 985 20 , , , cord-022526-j9kg00qf 985 21 the the DT cord-022526-j9kg00qf 985 22 prognosis prognosis NN cord-022526-j9kg00qf 985 23 remains remain VBZ cord-022526-j9kg00qf 985 24 guarded guard VBN cord-022526-j9kg00qf 985 25 . . . cord-022526-j9kg00qf 986 1 Two two CD cord-022526-j9kg00qf 986 2 young young JJ cord-022526-j9kg00qf 986 3 horses horse NNS cord-022526-j9kg00qf 986 4 with with IN cord-022526-j9kg00qf 986 5 granulomatous granulomatous JJ cord-022526-j9kg00qf 986 6 enteritis enteritis NN cord-022526-j9kg00qf 986 7 had have VBD cord-022526-j9kg00qf 986 8 the the DT cord-022526-j9kg00qf 986 9 thickened thickened JJ cord-022526-j9kg00qf 986 10 terminal terminal JJ cord-022526-j9kg00qf 986 11 small small JJ cord-022526-j9kg00qf 986 12 intestine intestine NN cord-022526-j9kg00qf 986 13 resected resect VBN cord-022526-j9kg00qf 986 14 with with IN cord-022526-j9kg00qf 986 15 positive positive JJ cord-022526-j9kg00qf 986 16 outcomes outcome NNS cord-022526-j9kg00qf 986 17 ; ; : cord-022526-j9kg00qf 986 18 one one CD cord-022526-j9kg00qf 986 19 survived survive VBD cord-022526-j9kg00qf 986 20 4 4 CD cord-022526-j9kg00qf 986 21 months month NNS cord-022526-j9kg00qf 986 22 , , , cord-022526-j9kg00qf 986 23 the the DT cord-022526-j9kg00qf 986 24 other other JJ cord-022526-j9kg00qf 986 25 has have VBZ cord-022526-j9kg00qf 986 26 a a DT cord-022526-j9kg00qf 986 27 follow follow NN cord-022526-j9kg00qf 986 28 up up RP cord-022526-j9kg00qf 986 29 extending extend VBG cord-022526-j9kg00qf 986 30 more more JJR cord-022526-j9kg00qf 986 31 than than IN cord-022526-j9kg00qf 986 32 10 10 CD cord-022526-j9kg00qf 986 33 years year NNS cord-022526-j9kg00qf 986 34 . . . cord-022526-j9kg00qf 987 1 20 20 CD cord-022526-j9kg00qf 987 2 _SP cord-022526-j9kg00qf 987 3 Anthony Anthony NNP cord-022526-j9kg00qf 987 4 T. T. NNP cord-022526-j9kg00qf 987 5 Blikslager Blikslager NNP cord-022526-j9kg00qf 988 1 To to TO cord-022526-j9kg00qf 988 2 gain gain VB cord-022526-j9kg00qf 988 3 an an DT cord-022526-j9kg00qf 988 4 appreciation appreciation NN cord-022526-j9kg00qf 988 5 of of IN cord-022526-j9kg00qf 988 6 the the DT cord-022526-j9kg00qf 988 7 mechanisms mechanism NNS cord-022526-j9kg00qf 988 8 whereby whereby WRB cord-022526-j9kg00qf 988 9 the the DT cord-022526-j9kg00qf 988 10 mucosa mucosa NN cord-022526-j9kg00qf 988 11 is be VBZ cord-022526-j9kg00qf 988 12 injured injure VBN cord-022526-j9kg00qf 988 13 and and CC cord-022526-j9kg00qf 988 14 subsequently subsequently RB cord-022526-j9kg00qf 988 15 repaired repair VBN cord-022526-j9kg00qf 988 16 , , , cord-022526-j9kg00qf 988 17 one one PRP cord-022526-j9kg00qf 988 18 must must MD cord-022526-j9kg00qf 988 19 understand understand VB cord-022526-j9kg00qf 988 20 how how WRB cord-022526-j9kg00qf 988 21 the the DT cord-022526-j9kg00qf 988 22 integrity integrity NN cord-022526-j9kg00qf 988 23 of of IN cord-022526-j9kg00qf 988 24 the the DT cord-022526-j9kg00qf 988 25 mucosa mucosa NN cord-022526-j9kg00qf 988 26 is be VBZ cord-022526-j9kg00qf 988 27 regulated regulate VBN cord-022526-j9kg00qf 988 28 physiologically physiologically RB cord-022526-j9kg00qf 988 29 . . . cord-022526-j9kg00qf 989 1 Regulation regulation NN cord-022526-j9kg00qf 989 2 of of IN cord-022526-j9kg00qf 989 3 mucosal mucosal JJ cord-022526-j9kg00qf 989 4 integrity integrity NN cord-022526-j9kg00qf 989 5 is be VBZ cord-022526-j9kg00qf 989 6 referred refer VBN cord-022526-j9kg00qf 989 7 to to IN cord-022526-j9kg00qf 989 8 as as RB cord-022526-j9kg00qf 989 9 mucosal mucosal JJ cord-022526-j9kg00qf 989 10 barrier barrier NN cord-022526-j9kg00qf 989 11 function function NN cord-022526-j9kg00qf 989 12 , , , cord-022526-j9kg00qf 989 13 which which WDT cord-022526-j9kg00qf 989 14 is be VBZ cord-022526-j9kg00qf 989 15 vital vital JJ cord-022526-j9kg00qf 989 16 because because IN cord-022526-j9kg00qf 989 17 it -PRON- PRP cord-022526-j9kg00qf 989 18 prevents prevent VBZ cord-022526-j9kg00qf 989 19 bacteria bacteria NNS cord-022526-j9kg00qf 989 20 and and CC cord-022526-j9kg00qf 989 21 associated associate VBD cord-022526-j9kg00qf 989 22 toxins toxin NNS cord-022526-j9kg00qf 989 23 from from IN cord-022526-j9kg00qf 989 24 gaining gain VBG cord-022526-j9kg00qf 989 25 access access NN cord-022526-j9kg00qf 989 26 to to IN cord-022526-j9kg00qf 989 27 subepithelial subepithelial JJ cord-022526-j9kg00qf 989 28 tissues tissue NNS cord-022526-j9kg00qf 989 29 and and CC cord-022526-j9kg00qf 989 30 the the DT cord-022526-j9kg00qf 989 31 circulation circulation NN cord-022526-j9kg00qf 989 32 . . . cord-022526-j9kg00qf 990 1 However however RB cord-022526-j9kg00qf 990 2 , , , cord-022526-j9kg00qf 990 3 the the DT cord-022526-j9kg00qf 990 4 mucosa mucosa NN cord-022526-j9kg00qf 990 5 has have VBZ cord-022526-j9kg00qf 990 6 two two CD cord-022526-j9kg00qf 990 7 conflicting conflict VBG cord-022526-j9kg00qf 990 8 functions function NNS cord-022526-j9kg00qf 990 9 : : : cord-022526-j9kg00qf 990 10 it -PRON- PRP cord-022526-j9kg00qf 990 11 must must MD cord-022526-j9kg00qf 990 12 serve serve VB cord-022526-j9kg00qf 990 13 as as IN cord-022526-j9kg00qf 990 14 a a DT cord-022526-j9kg00qf 990 15 protective protective JJ cord-022526-j9kg00qf 990 16 barrier barrier NN cord-022526-j9kg00qf 990 17 and and CC cord-022526-j9kg00qf 990 18 continue continue VBP cord-022526-j9kg00qf 990 19 to to TO cord-022526-j9kg00qf 990 20 absorb absorb VB cord-022526-j9kg00qf 990 21 solutes solute NNS cord-022526-j9kg00qf 990 22 necessary necessary JJ cord-022526-j9kg00qf 990 23 to to TO cord-022526-j9kg00qf 990 24 maintain maintain VB cord-022526-j9kg00qf 990 25 well well RB cord-022526-j9kg00qf 990 26 - - HYPH cord-022526-j9kg00qf 990 27 being being NN cord-022526-j9kg00qf 990 28 of of IN cord-022526-j9kg00qf 990 29 the the DT cord-022526-j9kg00qf 990 30 host host NN cord-022526-j9kg00qf 990 31 . . . cord-022526-j9kg00qf 991 1 This this DT cord-022526-j9kg00qf 991 2 conflict conflict NN cord-022526-j9kg00qf 991 3 is be VBZ cord-022526-j9kg00qf 991 4 most most RBS cord-022526-j9kg00qf 991 5 notable notable JJ cord-022526-j9kg00qf 991 6 at at IN cord-022526-j9kg00qf 991 7 the the DT cord-022526-j9kg00qf 991 8 intercellular intercellular JJ cord-022526-j9kg00qf 991 9 ( ( -LRB- cord-022526-j9kg00qf 991 10 paracellular paracellular NNP cord-022526-j9kg00qf 991 11 ) ) -RRB- cord-022526-j9kg00qf 991 12 space space NN cord-022526-j9kg00qf 991 13 , , , cord-022526-j9kg00qf 991 14 which which WDT cord-022526-j9kg00qf 991 15 allows allow VBZ cord-022526-j9kg00qf 991 16 passage passage NN cord-022526-j9kg00qf 991 17 of of IN cord-022526-j9kg00qf 991 18 select select JJ cord-022526-j9kg00qf 991 19 solutes solute NNS cord-022526-j9kg00qf 991 20 and and CC cord-022526-j9kg00qf 991 21 water water NN cord-022526-j9kg00qf 991 22 , , , cord-022526-j9kg00qf 991 23 1 1 CD cord-022526-j9kg00qf 991 24 - - SYM cord-022526-j9kg00qf 991 25 4 4 CD cord-022526-j9kg00qf 992 1 but but CC cord-022526-j9kg00qf 992 2 which which WDT cord-022526-j9kg00qf 992 3 does do VBZ cord-022526-j9kg00qf 992 4 not not RB cord-022526-j9kg00qf 992 5 admit admit VB cord-022526-j9kg00qf 992 6 large large JJ cord-022526-j9kg00qf 992 7 molecules molecule NNS cord-022526-j9kg00qf 992 8 , , , cord-022526-j9kg00qf 992 9 including include VBG cord-022526-j9kg00qf 992 10 bacterial bacterial JJ cord-022526-j9kg00qf 992 11 toxins toxin NNS cord-022526-j9kg00qf 992 12 . . . cord-022526-j9kg00qf 993 1 5 5 LS cord-022526-j9kg00qf 994 1 The the DT cord-022526-j9kg00qf 994 2 paracellular paracellular JJ cord-022526-j9kg00qf 994 3 space space NN cord-022526-j9kg00qf 994 4 is be VBZ cord-022526-j9kg00qf 994 5 regulated regulate VBN cord-022526-j9kg00qf 994 6 almost almost RB cord-022526-j9kg00qf 994 7 exclusively exclusively RB cord-022526-j9kg00qf 994 8 by by IN cord-022526-j9kg00qf 994 9 the the DT cord-022526-j9kg00qf 994 10 tight tight JJ cord-022526-j9kg00qf 994 11 junction junction NN cord-022526-j9kg00qf 994 12 , , , cord-022526-j9kg00qf 994 13 6 6 CD cord-022526-j9kg00qf 994 14 which which WDT cord-022526-j9kg00qf 994 15 is be VBZ cord-022526-j9kg00qf 994 16 the the DT cord-022526-j9kg00qf 994 17 interepithelial interepithelial JJ cord-022526-j9kg00qf 994 18 junction junction NN cord-022526-j9kg00qf 994 19 at at IN cord-022526-j9kg00qf 994 20 the the DT cord-022526-j9kg00qf 994 21 apical apical RB cord-022526-j9kg00qf 994 22 - - HYPH cord-022526-j9kg00qf 994 23 most most JJS cord-022526-j9kg00qf 994 24 aspect aspect NN cord-022526-j9kg00qf 994 25 of of IN cord-022526-j9kg00qf 994 26 the the DT cord-022526-j9kg00qf 994 27 paracellular paracellular JJ cord-022526-j9kg00qf 994 28 space space NN cord-022526-j9kg00qf 994 29 . . . cord-022526-j9kg00qf 995 1 Although although IN cord-022526-j9kg00qf 995 2 these these DT cord-022526-j9kg00qf 995 3 tight tight JJ cord-022526-j9kg00qf 995 4 junctions junction NNS cord-022526-j9kg00qf 995 5 originally originally RB cord-022526-j9kg00qf 995 6 were be VBD cord-022526-j9kg00qf 995 7 viewed view VBN cord-022526-j9kg00qf 995 8 as as IN cord-022526-j9kg00qf 995 9 inert inert JJ cord-022526-j9kg00qf 995 10 cellular cellular JJ cord-022526-j9kg00qf 995 11 adhesion adhesion NN cord-022526-j9kg00qf 995 12 sites site NNS cord-022526-j9kg00qf 995 13 , , , cord-022526-j9kg00qf 995 14 what what WP cord-022526-j9kg00qf 995 15 has have VBZ cord-022526-j9kg00qf 995 16 become become VBN cord-022526-j9kg00qf 995 17 clear clear JJ cord-022526-j9kg00qf 995 18 in in IN cord-022526-j9kg00qf 995 19 recent recent JJ cord-022526-j9kg00qf 995 20 years year NNS cord-022526-j9kg00qf 995 21 is be VBZ cord-022526-j9kg00qf 995 22 that that IN cord-022526-j9kg00qf 995 23 tight tight JJ cord-022526-j9kg00qf 995 24 junction junction NN cord-022526-j9kg00qf 995 25 permeability permeability NN cord-022526-j9kg00qf 995 26 depends depend VBZ cord-022526-j9kg00qf 995 27 on on IN cord-022526-j9kg00qf 995 28 tissue tissue NN cord-022526-j9kg00qf 995 29 - - HYPH cord-022526-j9kg00qf 995 30 specific specific JJ cord-022526-j9kg00qf 995 31 molecular molecular JJ cord-022526-j9kg00qf 995 32 structure structure NN cord-022526-j9kg00qf 995 33 and and CC cord-022526-j9kg00qf 995 34 is be VBZ cord-022526-j9kg00qf 995 35 regulated regulate VBN cord-022526-j9kg00qf 995 36 by by IN cord-022526-j9kg00qf 995 37 a a DT cord-022526-j9kg00qf 995 38 complex complex JJ cord-022526-j9kg00qf 995 39 array array NN cord-022526-j9kg00qf 995 40 of of IN cord-022526-j9kg00qf 995 41 intracellular intracellular JJ cord-022526-j9kg00qf 995 42 proteins protein NNS cord-022526-j9kg00qf 995 43 and and CC cord-022526-j9kg00qf 995 44 the the DT cord-022526-j9kg00qf 995 45 cytoskeleton cytoskeleton NN cord-022526-j9kg00qf 995 46 . . . cord-022526-j9kg00qf 996 1 Tight tight JJ cord-022526-j9kg00qf 996 2 junctions junction NNS cord-022526-j9kg00qf 996 3 consist consist VBP cord-022526-j9kg00qf 996 4 of of IN cord-022526-j9kg00qf 996 5 a a DT cord-022526-j9kg00qf 996 6 group group NN cord-022526-j9kg00qf 996 7 of of IN cord-022526-j9kg00qf 996 8 transmembrane transmembrane NN cord-022526-j9kg00qf 996 9 proteins protein NNS cord-022526-j9kg00qf 996 10 that that WDT cord-022526-j9kg00qf 996 11 interdigitate interdigitate VBP cord-022526-j9kg00qf 996 12 from from IN cord-022526-j9kg00qf 996 13 adjacent adjacent JJ cord-022526-j9kg00qf 996 14 cells cell NNS cord-022526-j9kg00qf 996 15 . . . cord-022526-j9kg00qf 997 1 Although although IN cord-022526-j9kg00qf 997 2 occludin occludin NNP cord-022526-j9kg00qf 997 3 originally originally RB cord-022526-j9kg00qf 997 4 was be VBD cord-022526-j9kg00qf 997 5 thought think VBN cord-022526-j9kg00qf 997 6 to to TO cord-022526-j9kg00qf 997 7 be be VB cord-022526-j9kg00qf 997 8 the the DT cord-022526-j9kg00qf 997 9 predominant predominant JJ cord-022526-j9kg00qf 997 10 tight tight JJ cord-022526-j9kg00qf 997 11 junction junction NN cord-022526-j9kg00qf 997 12 transmembrane transmembrane NN cord-022526-j9kg00qf 997 13 protein protein NN cord-022526-j9kg00qf 997 14 , , , cord-022526-j9kg00qf 997 15 a a DT cord-022526-j9kg00qf 997 16 group group NN cord-022526-j9kg00qf 997 17 of of IN cord-022526-j9kg00qf 997 18 proteins protein NNS cord-022526-j9kg00qf 997 19 termed term VBD cord-022526-j9kg00qf 997 20 claudins claudin NNS cord-022526-j9kg00qf 997 21 appear appear VBP cord-022526-j9kg00qf 997 22 to to TO cord-022526-j9kg00qf 997 23 be be VB cord-022526-j9kg00qf 997 24 more more RBR cord-022526-j9kg00qf 997 25 critical critical JJ cord-022526-j9kg00qf 997 26 . . . cord-022526-j9kg00qf 998 1 7 7 CD cord-022526-j9kg00qf 999 1 These these DT cord-022526-j9kg00qf 999 2 transmembrane transmembrane NN cord-022526-j9kg00qf 999 3 proteins protein NNS cord-022526-j9kg00qf 999 4 interact interact VBP cord-022526-j9kg00qf 999 5 with with IN cord-022526-j9kg00qf 999 6 the the DT cord-022526-j9kg00qf 999 7 cytoskeleton cytoskeleton NN cord-022526-j9kg00qf 999 8 via via IN cord-022526-j9kg00qf 999 9 a a DT cord-022526-j9kg00qf 999 10 series series NN cord-022526-j9kg00qf 999 11 of of IN cord-022526-j9kg00qf 999 12 intracellular intracellular JJ cord-022526-j9kg00qf 999 13 proteins protein NNS cord-022526-j9kg00qf 999 14 , , , cord-022526-j9kg00qf 999 15 including include VBG cord-022526-j9kg00qf 999 16 zonula zonula NNP cord-022526-j9kg00qf 999 17 occludens occludens NNP cord-022526-j9kg00qf 999 18 1 1 CD cord-022526-j9kg00qf 999 19 , , , cord-022526-j9kg00qf 999 20 2 2 CD cord-022526-j9kg00qf 999 21 , , , cord-022526-j9kg00qf 999 22 and and CC cord-022526-j9kg00qf 999 23 3 3 CD cord-022526-j9kg00qf 999 24 ; ; : cord-022526-j9kg00qf 999 25 cingulin cingulin NNP cord-022526-j9kg00qf 999 26 ; ; : cord-022526-j9kg00qf 999 27 and and CC cord-022526-j9kg00qf 999 28 others other NNS cord-022526-j9kg00qf 999 29 . . . cord-022526-j9kg00qf 1000 1 8 8 CD cord-022526-j9kg00qf 1001 1 In in IN cord-022526-j9kg00qf 1001 2 addition addition NN cord-022526-j9kg00qf 1001 3 , , , cord-022526-j9kg00qf 1001 4 local local JJ cord-022526-j9kg00qf 1001 5 regulatory regulatory JJ cord-022526-j9kg00qf 1001 6 proteins protein NNS cord-022526-j9kg00qf 1001 7 such such JJ cord-022526-j9kg00qf 1001 8 as as IN cord-022526-j9kg00qf 1001 9 the the DT cord-022526-j9kg00qf 1001 10 small small JJ cord-022526-j9kg00qf 1001 11 guanosine guanosine NN cord-022526-j9kg00qf 1001 12 triphosphatase triphosphatase NN cord-022526-j9kg00qf 1001 13 - - HYPH cord-022526-j9kg00qf 1001 14 Rho rho NN cord-022526-j9kg00qf 1001 15 are be VBP cord-022526-j9kg00qf 1001 16 also also RB cord-022526-j9kg00qf 1001 17 critical critical JJ cord-022526-j9kg00qf 1001 18 to to IN cord-022526-j9kg00qf 1001 19 tight tight JJ cord-022526-j9kg00qf 1001 20 junction junction NN cord-022526-j9kg00qf 1001 21 function function NN cord-022526-j9kg00qf 1001 22 . . . cord-022526-j9kg00qf 1002 1 In in IN cord-022526-j9kg00qf 1002 2 general general JJ cord-022526-j9kg00qf 1002 3 the the DT cord-022526-j9kg00qf 1002 4 relative relative JJ cord-022526-j9kg00qf 1002 5 contractile contractile JJ cord-022526-j9kg00qf 1002 6 state state NN cord-022526-j9kg00qf 1002 7 of of IN cord-022526-j9kg00qf 1002 8 the the DT cord-022526-j9kg00qf 1002 9 actin actin NN cord-022526-j9kg00qf 1002 10 cytoskeleton cytoskeleton NN cord-022526-j9kg00qf 1002 11 determines determine VBZ cord-022526-j9kg00qf 1002 12 the the DT cord-022526-j9kg00qf 1002 13 degree degree NN cord-022526-j9kg00qf 1002 14 to to TO cord-022526-j9kg00qf 1002 15 which which WDT cord-022526-j9kg00qf 1002 16 tight tight JJ cord-022526-j9kg00qf 1002 17 junctions junction NNS cord-022526-j9kg00qf 1002 18 are be VBP cord-022526-j9kg00qf 1002 19 open open JJ cord-022526-j9kg00qf 1002 20 or or CC cord-022526-j9kg00qf 1002 21 closed closed JJ cord-022526-j9kg00qf 1002 22 , , , cord-022526-j9kg00qf 1002 23 but but CC cord-022526-j9kg00qf 1002 24 the the DT cord-022526-j9kg00qf 1002 25 complexities complexity NNS cord-022526-j9kg00qf 1002 26 of of IN cord-022526-j9kg00qf 1002 27 regulation regulation NN cord-022526-j9kg00qf 1002 28 of of IN cord-022526-j9kg00qf 1002 29 this this DT cord-022526-j9kg00qf 1002 30 process process NN cord-022526-j9kg00qf 1002 31 are be VBP cord-022526-j9kg00qf 1002 32 understood understand VBN cord-022526-j9kg00qf 1002 33 poorly poorly RB cord-022526-j9kg00qf 1002 34 . . . cord-022526-j9kg00qf 1003 1 9 9 CD cord-022526-j9kg00qf 1003 2 , , , cord-022526-j9kg00qf 1003 3 10 10 CD cord-022526-j9kg00qf 1003 4 The the DT cord-022526-j9kg00qf 1003 5 most most RBS cord-022526-j9kg00qf 1003 6 sensitive sensitive JJ cord-022526-j9kg00qf 1003 7 measure measure NN cord-022526-j9kg00qf 1003 8 of of IN cord-022526-j9kg00qf 1003 9 mucosal mucosal JJ cord-022526-j9kg00qf 1003 10 barrier barrier NN cord-022526-j9kg00qf 1003 11 function function NN cord-022526-j9kg00qf 1003 12 is be VBZ cord-022526-j9kg00qf 1003 13 transepithelial transepithelial JJ cord-022526-j9kg00qf 1003 14 electric electric JJ cord-022526-j9kg00qf 1003 15 resistance resistance NN cord-022526-j9kg00qf 1003 16 , , , cord-022526-j9kg00qf 1003 17 which which WDT cord-022526-j9kg00qf 1003 18 is be VBZ cord-022526-j9kg00qf 1003 19 measured measure VBN cord-022526-j9kg00qf 1003 20 by by IN cord-022526-j9kg00qf 1003 21 mounting mount VBG cord-022526-j9kg00qf 1003 22 mucosa mucosa NN cord-022526-j9kg00qf 1003 23 in in IN cord-022526-j9kg00qf 1003 24 an an DT cord-022526-j9kg00qf 1003 25 ex ex FW cord-022526-j9kg00qf 1003 26 vivo vivo NN cord-022526-j9kg00qf 1003 27 system system NN cord-022526-j9kg00qf 1003 28 called call VBD cord-022526-j9kg00qf 1003 29 an an DT cord-022526-j9kg00qf 1003 30 Ussing Ussing NNP cord-022526-j9kg00qf 1003 31 chamber chamber NN cord-022526-j9kg00qf 1003 32 , , , cord-022526-j9kg00qf 1003 33 because because IN cord-022526-j9kg00qf 1003 34 this this DT cord-022526-j9kg00qf 1003 35 measurement measurement NN cord-022526-j9kg00qf 1003 36 is be VBZ cord-022526-j9kg00qf 1003 37 largely largely RB cord-022526-j9kg00qf 1003 38 a a DT cord-022526-j9kg00qf 1003 39 reflection reflection NN cord-022526-j9kg00qf 1003 40 of of IN cord-022526-j9kg00qf 1003 41 the the DT cord-022526-j9kg00qf 1003 42 permeability permeability NN cord-022526-j9kg00qf 1003 43 of of IN cord-022526-j9kg00qf 1003 44 mucosa mucosa NN cord-022526-j9kg00qf 1003 45 to to IN cord-022526-j9kg00qf 1003 46 ions ion NNS cord-022526-j9kg00qf 1003 47 . . . cord-022526-j9kg00qf 1004 1 11 11 CD cord-022526-j9kg00qf 1004 2 , , , cord-022526-j9kg00qf 1004 3 12 12 CD cord-022526-j9kg00qf 1004 4 Ions ion NNS cord-022526-j9kg00qf 1004 5 may may MD cord-022526-j9kg00qf 1004 6 follow follow VB cord-022526-j9kg00qf 1004 7 one one CD cord-022526-j9kg00qf 1004 8 of of IN cord-022526-j9kg00qf 1004 9 two two CD cord-022526-j9kg00qf 1004 10 routes route NNS cord-022526-j9kg00qf 1004 11 when when WRB cord-022526-j9kg00qf 1004 12 traversing traverse VBG cord-022526-j9kg00qf 1004 13 epithelium epithelium NN cord-022526-j9kg00qf 1004 14 : : : cord-022526-j9kg00qf 1004 15 transcellular transcellular NNP cord-022526-j9kg00qf 1004 16 and and CC cord-022526-j9kg00qf 1004 17 paracellular paracellular NNP cord-022526-j9kg00qf 1004 18 . . . cord-022526-j9kg00qf 1005 1 5 5 LS cord-022526-j9kg00qf 1006 1 Because because IN cord-022526-j9kg00qf 1006 2 cell cell NN cord-022526-j9kg00qf 1006 3 membranes membrane NNS cord-022526-j9kg00qf 1006 4 have have VBP cord-022526-j9kg00qf 1006 5 a a DT cord-022526-j9kg00qf 1006 6 resistance resistance NN cord-022526-j9kg00qf 1006 7 to to IN cord-022526-j9kg00qf 1006 8 passive passive JJ cord-022526-j9kg00qf 1006 9 flow flow NN cord-022526-j9kg00qf 1006 10 of of IN cord-022526-j9kg00qf 1006 11 ions ion NNS cord-022526-j9kg00qf 1006 12 1.5 1.5 CD cord-022526-j9kg00qf 1006 13 to to TO cord-022526-j9kg00qf 1006 14 3 3 CD cord-022526-j9kg00qf 1006 15 log log NN cord-022526-j9kg00qf 1006 16 units unit NNS cord-022526-j9kg00qf 1006 17 greater great JJR cord-022526-j9kg00qf 1006 18 than than IN cord-022526-j9kg00qf 1006 19 that that DT cord-022526-j9kg00qf 1006 20 of of IN cord-022526-j9kg00qf 1006 21 the the DT cord-022526-j9kg00qf 1006 22 epithelium epithelium NN cord-022526-j9kg00qf 1006 23 as as IN cord-022526-j9kg00qf 1006 24 a a DT cord-022526-j9kg00qf 1006 25 whole whole NN cord-022526-j9kg00qf 1006 26 , , , cord-022526-j9kg00qf 1006 27 measurements measurement NNS cord-022526-j9kg00qf 1006 28 of of IN cord-022526-j9kg00qf 1006 29 transepithelial transepithelial JJ cord-022526-j9kg00qf 1006 30 resistance resistance NN cord-022526-j9kg00qf 1006 31 largely largely RB cord-022526-j9kg00qf 1006 32 reflect reflect VBP cord-022526-j9kg00qf 1006 33 the the DT cord-022526-j9kg00qf 1006 34 resistance resistance NN cord-022526-j9kg00qf 1006 35 of of IN cord-022526-j9kg00qf 1006 36 the the DT cord-022526-j9kg00qf 1006 37 paracellular paracellular JJ cord-022526-j9kg00qf 1006 38 space space NN cord-022526-j9kg00qf 1006 39 , , , cord-022526-j9kg00qf 1006 40 and and CC cord-022526-j9kg00qf 1006 41 in in IN cord-022526-j9kg00qf 1006 42 particular particular JJ cord-022526-j9kg00qf 1006 43 the the DT cord-022526-j9kg00qf 1006 44 tight tight JJ cord-022526-j9kg00qf 1006 45 junctions junction NNS cord-022526-j9kg00qf 1006 46 that that WDT cord-022526-j9kg00qf 1006 47 regulate regulate VBP cord-022526-j9kg00qf 1006 48 paracellular paracellular JJ cord-022526-j9kg00qf 1006 49 flow flow NN cord-022526-j9kg00qf 1006 50 of of IN cord-022526-j9kg00qf 1006 51 ions ion NNS cord-022526-j9kg00qf 1006 52 . . . cord-022526-j9kg00qf 1007 1 12 12 CD cord-022526-j9kg00qf 1008 1 Because because IN cord-022526-j9kg00qf 1008 2 tight tight JJ cord-022526-j9kg00qf 1008 3 junctions junction NNS cord-022526-j9kg00qf 1008 4 differ differ VBP cord-022526-j9kg00qf 1008 5 in in IN cord-022526-j9kg00qf 1008 6 structure structure NN cord-022526-j9kg00qf 1008 7 from from IN cord-022526-j9kg00qf 1008 8 different different JJ cord-022526-j9kg00qf 1008 9 portions portion NNS cord-022526-j9kg00qf 1008 10 of of IN cord-022526-j9kg00qf 1008 11 the the DT cord-022526-j9kg00qf 1008 12 mucosa mucosa NN cord-022526-j9kg00qf 1008 13 , , , cord-022526-j9kg00qf 1008 14 13 13 CD cord-022526-j9kg00qf 1008 15 measurements measurement NNS cord-022526-j9kg00qf 1008 16 of of IN cord-022526-j9kg00qf 1008 17 transepithelial transepithelial JJ cord-022526-j9kg00qf 1008 18 resistance resistance NN cord-022526-j9kg00qf 1008 19 reflect reflect VBP cord-022526-j9kg00qf 1008 20 the the DT cord-022526-j9kg00qf 1008 21 net net JJ cord-022526-j9kg00qf 1008 22 resistance resistance NN cord-022526-j9kg00qf 1008 23 of of IN cord-022526-j9kg00qf 1008 24 epithelium epithelium NN cord-022526-j9kg00qf 1008 25 of of IN cord-022526-j9kg00qf 1008 26 variable variable JJ cord-022526-j9kg00qf 1008 27 permeability permeability NN cord-022526-j9kg00qf 1008 28 within within IN cord-022526-j9kg00qf 1008 29 a a DT cord-022526-j9kg00qf 1008 30 given give VBN cord-022526-j9kg00qf 1008 31 tissue tissue NN cord-022526-j9kg00qf 1008 32 . . . cord-022526-j9kg00qf 1009 1 For for IN cord-022526-j9kg00qf 1009 2 example example NN cord-022526-j9kg00qf 1009 3 , , , cord-022526-j9kg00qf 1009 4 tight tight JJ cord-022526-j9kg00qf 1009 5 junctions junction NNS cord-022526-j9kg00qf 1009 6 in in IN cord-022526-j9kg00qf 1009 7 the the DT cord-022526-j9kg00qf 1009 8 intestinal intestinal JJ cord-022526-j9kg00qf 1009 9 glandular glandular JJ cord-022526-j9kg00qf 1009 10 structures structure NNS cord-022526-j9kg00qf 1009 11 called call VBD cord-022526-j9kg00qf 1009 12 crypts crypt NNS cord-022526-j9kg00qf 1009 13 are be VBP cord-022526-j9kg00qf 1009 14 leakier leaky JJR cord-022526-j9kg00qf 1009 15 than than IN cord-022526-j9kg00qf 1009 16 those those DT cord-022526-j9kg00qf 1009 17 in in IN cord-022526-j9kg00qf 1009 18 the the DT cord-022526-j9kg00qf 1009 19 surface surface NN cord-022526-j9kg00qf 1009 20 epithelium epithelium NN cord-022526-j9kg00qf 1009 21 because because IN cord-022526-j9kg00qf 1009 22 of of IN cord-022526-j9kg00qf 1009 23 fewer few JJR cord-022526-j9kg00qf 1009 24 and and CC cord-022526-j9kg00qf 1009 25 less less RBR cord-022526-j9kg00qf 1009 26 organized organized JJ cord-022526-j9kg00qf 1009 27 tight tight JJ cord-022526-j9kg00qf 1009 28 junction junction NN cord-022526-j9kg00qf 1009 29 strands strand NNS cord-022526-j9kg00qf 1009 30 . . . cord-022526-j9kg00qf 1010 1 11 11 CD cord-022526-j9kg00qf 1010 2 , , , cord-022526-j9kg00qf 1010 3 14 14 CD cord-022526-j9kg00qf 1010 4 Conversely conversely RB cord-022526-j9kg00qf 1010 5 , , , cord-022526-j9kg00qf 1010 6 surface surface NN cord-022526-j9kg00qf 1010 7 epithelium epithelium NN cord-022526-j9kg00qf 1010 8 has have VBZ cord-022526-j9kg00qf 1010 9 a a DT cord-022526-j9kg00qf 1010 10 greater great JJR cord-022526-j9kg00qf 1010 11 number number NN cord-022526-j9kg00qf 1010 12 of of IN cord-022526-j9kg00qf 1010 13 well well RB cord-022526-j9kg00qf 1010 14 - - HYPH cord-022526-j9kg00qf 1010 15 organized organize VBN cord-022526-j9kg00qf 1010 16 tight tight JJ cord-022526-j9kg00qf 1010 17 junction junction NN cord-022526-j9kg00qf 1010 18 strands strand NNS cord-022526-j9kg00qf 1010 19 that that WDT cord-022526-j9kg00qf 1010 20 result result VBP cord-022526-j9kg00qf 1010 21 in in IN cord-022526-j9kg00qf 1010 22 epithelium epithelium NN cord-022526-j9kg00qf 1010 23 with with IN cord-022526-j9kg00qf 1010 24 a a DT cord-022526-j9kg00qf 1010 25 high high JJ cord-022526-j9kg00qf 1010 26 resistance resistance NN cord-022526-j9kg00qf 1010 27 . . . cord-022526-j9kg00qf 1011 1 11 11 CD cord-022526-j9kg00qf 1012 1 This this DT cord-022526-j9kg00qf 1012 2 correlates correlate VBZ cord-022526-j9kg00qf 1012 3 well well RB cord-022526-j9kg00qf 1012 4 with with IN cord-022526-j9kg00qf 1012 5 the the DT cord-022526-j9kg00qf 1012 6 absorptive absorptive JJ cord-022526-j9kg00qf 1012 7 function function NN cord-022526-j9kg00qf 1012 8 of of IN cord-022526-j9kg00qf 1012 9 epithelium epithelium NN cord-022526-j9kg00qf 1012 10 located locate VBN cord-022526-j9kg00qf 1012 11 on on IN cord-022526-j9kg00qf 1012 12 the the DT cord-022526-j9kg00qf 1012 13 mucosal mucosal JJ cord-022526-j9kg00qf 1012 14 surface surface NN cord-022526-j9kg00qf 1012 15 and and CC cord-022526-j9kg00qf 1012 16 the the DT cord-022526-j9kg00qf 1012 17 secretory secretory JJ cord-022526-j9kg00qf 1012 18 function function NN cord-022526-j9kg00qf 1012 19 of of IN cord-022526-j9kg00qf 1012 20 crypt crypt JJ cord-022526-j9kg00qf 1012 21 epithelium epithelium NN cord-022526-j9kg00qf 1012 22 . . . cord-022526-j9kg00qf 1013 1 Structure structure NN cord-022526-j9kg00qf 1013 2 of of IN cord-022526-j9kg00qf 1013 3 tight tight JJ cord-022526-j9kg00qf 1013 4 junctions junction NNS cord-022526-j9kg00qf 1013 5 also also RB cord-022526-j9kg00qf 1013 6 varies vary VBZ cord-022526-j9kg00qf 1013 7 with with IN cord-022526-j9kg00qf 1013 8 the the DT cord-022526-j9kg00qf 1013 9 segment segment NN cord-022526-j9kg00qf 1013 10 of of IN cord-022526-j9kg00qf 1013 11 intestine intestine NN cord-022526-j9kg00qf 1013 12 . . . cord-022526-j9kg00qf 1014 1 For for IN cord-022526-j9kg00qf 1014 2 example example NN cord-022526-j9kg00qf 1014 3 , , , cord-022526-j9kg00qf 1014 4 tight tight JJ cord-022526-j9kg00qf 1014 5 junctions junction NNS cord-022526-j9kg00qf 1014 6 have have VBP cord-022526-j9kg00qf 1014 7 more more JJR cord-022526-j9kg00qf 1014 8 strands strand NNS cord-022526-j9kg00qf 1014 9 in in IN cord-022526-j9kg00qf 1014 10 the the DT cord-022526-j9kg00qf 1014 11 ileum ileum NN cord-022526-j9kg00qf 1014 12 than than IN cord-022526-j9kg00qf 1014 13 in in IN cord-022526-j9kg00qf 1014 14 the the DT cord-022526-j9kg00qf 1014 15 jejunum jejunum NNS cord-022526-j9kg00qf 1014 16 , , , cord-022526-j9kg00qf 1014 17 which which WDT cord-022526-j9kg00qf 1014 18 is be VBZ cord-022526-j9kg00qf 1014 19 reflected reflect VBN cord-022526-j9kg00qf 1014 20 by by IN cord-022526-j9kg00qf 1014 21 a a DT cord-022526-j9kg00qf 1014 22 higher high JJR cord-022526-j9kg00qf 1014 23 transepithelial transepithelial JJ cord-022526-j9kg00qf 1014 24 resistance resistance NN cord-022526-j9kg00qf 1014 25 in in IN cord-022526-j9kg00qf 1014 26 the the DT cord-022526-j9kg00qf 1014 27 ileum ileum NN cord-022526-j9kg00qf 1014 28 . . . cord-022526-j9kg00qf 1015 1 15 15 CD cord-022526-j9kg00qf 1015 2 _SP cord-022526-j9kg00qf 1016 1 The the DT cord-022526-j9kg00qf 1016 2 stomach stomach NN cord-022526-j9kg00qf 1016 3 has have VBZ cord-022526-j9kg00qf 1016 4 four four CD cord-022526-j9kg00qf 1016 5 regions region NNS cord-022526-j9kg00qf 1016 6 based base VBN cord-022526-j9kg00qf 1016 7 on on IN cord-022526-j9kg00qf 1016 8 the the DT cord-022526-j9kg00qf 1016 9 type type NN cord-022526-j9kg00qf 1016 10 of of IN cord-022526-j9kg00qf 1016 11 mucosal mucosal JJ cord-022526-j9kg00qf 1016 12 lining lining NN cord-022526-j9kg00qf 1016 13 ( ( -LRB- cord-022526-j9kg00qf 1016 14 in in IN cord-022526-j9kg00qf 1016 15 an an DT cord-022526-j9kg00qf 1016 16 orad orad NN cord-022526-j9kg00qf 1016 17 to to IN cord-022526-j9kg00qf 1016 18 aborad aborad NNP cord-022526-j9kg00qf 1016 19 order order NN cord-022526-j9kg00qf 1016 20 ) ) -RRB- cord-022526-j9kg00qf 1016 21 : : : cord-022526-j9kg00qf 1016 22 nonglandular nonglandular JJ cord-022526-j9kg00qf 1016 23 stratified stratified JJ cord-022526-j9kg00qf 1016 24 squamous squamous JJ cord-022526-j9kg00qf 1016 25 epithelium epithelium NN cord-022526-j9kg00qf 1016 26 , , , cord-022526-j9kg00qf 1016 27 cardiac cardiac JJ cord-022526-j9kg00qf 1016 28 epithelium epithelium NN cord-022526-j9kg00qf 1016 29 , , , cord-022526-j9kg00qf 1016 30 proper proper JJ cord-022526-j9kg00qf 1016 31 gastric gastric JJ cord-022526-j9kg00qf 1016 32 mucosa mucosa NN cord-022526-j9kg00qf 1016 33 , , , cord-022526-j9kg00qf 1016 34 and and CC cord-022526-j9kg00qf 1016 35 pyloric pyloric JJ cord-022526-j9kg00qf 1016 36 mucosa mucosa NN cord-022526-j9kg00qf 1016 37 . . . cord-022526-j9kg00qf 1017 1 16 16 CD cord-022526-j9kg00qf 1017 2 Stratified stratified JJ cord-022526-j9kg00qf 1017 3 squamous squamous JJ cord-022526-j9kg00qf 1017 4 epithelium epithelium NN cord-022526-j9kg00qf 1017 5 has have VBZ cord-022526-j9kg00qf 1017 6 distinct distinct JJ cord-022526-j9kg00qf 1017 7 differences difference NNS cord-022526-j9kg00qf 1017 8 in in IN cord-022526-j9kg00qf 1017 9 terms term NNS cord-022526-j9kg00qf 1017 10 of of IN cord-022526-j9kg00qf 1017 11 barrier barrier NN cord-022526-j9kg00qf 1017 12 function function NN cord-022526-j9kg00qf 1017 13 compared compare VBN cord-022526-j9kg00qf 1017 14 with with IN cord-022526-j9kg00qf 1017 15 the the DT cord-022526-j9kg00qf 1017 16 remainder remainder NN cord-022526-j9kg00qf 1017 17 of of IN cord-022526-j9kg00qf 1017 18 the the DT cord-022526-j9kg00qf 1017 19 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1017 20 tract tract NN cord-022526-j9kg00qf 1017 21 . . . cord-022526-j9kg00qf 1018 1 This this DT cord-022526-j9kg00qf 1018 2 epithelium epithelium NN cord-022526-j9kg00qf 1018 3 has have VBZ cord-022526-j9kg00qf 1018 4 baseline baseline JJ cord-022526-j9kg00qf 1018 5 transepithelial transepithelial JJ cord-022526-j9kg00qf 1018 6 resistance resistance NN cord-022526-j9kg00qf 1018 7 measurements measurement NNS cord-022526-j9kg00qf 1018 8 of of IN cord-022526-j9kg00qf 1018 9 approximately approximately RB cord-022526-j9kg00qf 1018 10 2000 2000 CD cord-022526-j9kg00qf 1018 11 to to IN cord-022526-j9kg00qf 1018 12 3000 3000 CD cord-022526-j9kg00qf 1018 13 Ω/cm Ω/cm NNP cord-022526-j9kg00qf 1018 14 2 2 CD cord-022526-j9kg00qf 1018 15 , , , cord-022526-j9kg00qf 1018 16 which which WDT cord-022526-j9kg00qf 1018 17 is be VBZ cord-022526-j9kg00qf 1018 18 an an DT cord-022526-j9kg00qf 1018 19 order order NN cord-022526-j9kg00qf 1018 20 of of IN cord-022526-j9kg00qf 1018 21 magnitude magnitude NN cord-022526-j9kg00qf 1018 22 higher high JJR cord-022526-j9kg00qf 1018 23 than than IN cord-022526-j9kg00qf 1018 24 the the DT cord-022526-j9kg00qf 1018 25 adjacent adjacent JJ cord-022526-j9kg00qf 1018 26 cardiac cardiac JJ cord-022526-j9kg00qf 1018 27 mucosa mucosa NN cord-022526-j9kg00qf 1018 28 . . . cord-022526-j9kg00qf 1019 1 17 17 CD cord-022526-j9kg00qf 1019 2 , , , cord-022526-j9kg00qf 1019 3 18 18 CD cord-022526-j9kg00qf 1020 1 Thus thus RB cord-022526-j9kg00qf 1020 2 the the DT cord-022526-j9kg00qf 1020 3 stratified stratified JJ cord-022526-j9kg00qf 1020 4 squamous squamous JJ cord-022526-j9kg00qf 1020 5 mucosa mucosa NN cord-022526-j9kg00qf 1020 6 is be VBZ cord-022526-j9kg00qf 1020 7 exceptionally exceptionally RB cord-022526-j9kg00qf 1020 8 impermeable impermeable JJ cord-022526-j9kg00qf 1020 9 . . . cord-022526-j9kg00qf 1021 1 This this DT cord-022526-j9kg00qf 1021 2 in in IN cord-022526-j9kg00qf 1021 3 effect effect NN cord-022526-j9kg00qf 1021 4 is be VBZ cord-022526-j9kg00qf 1021 5 the the DT cord-022526-j9kg00qf 1021 6 only only JJ cord-022526-j9kg00qf 1021 7 mechanism mechanism NN cord-022526-j9kg00qf 1021 8 this this DT cord-022526-j9kg00qf 1021 9 mucosa mucosa NN cord-022526-j9kg00qf 1021 10 has have VBZ cord-022526-j9kg00qf 1021 11 to to TO cord-022526-j9kg00qf 1021 12 defend defend VB cord-022526-j9kg00qf 1021 13 itself -PRON- PRP cord-022526-j9kg00qf 1021 14 against against IN cord-022526-j9kg00qf 1021 15 injury injury NN cord-022526-j9kg00qf 1021 16 . . . cord-022526-j9kg00qf 1022 1 The the DT cord-022526-j9kg00qf 1022 2 stratified stratified JJ cord-022526-j9kg00qf 1022 3 squamous squamous JJ cord-022526-j9kg00qf 1022 4 epithelium epithelium NN cord-022526-j9kg00qf 1022 5 consists consist VBZ cord-022526-j9kg00qf 1022 6 of of IN cord-022526-j9kg00qf 1022 7 four four CD cord-022526-j9kg00qf 1022 8 layers layer NNS cord-022526-j9kg00qf 1022 9 : : : cord-022526-j9kg00qf 1022 10 the the DT cord-022526-j9kg00qf 1022 11 outer outer JJ cord-022526-j9kg00qf 1022 12 stratum stratum NN cord-022526-j9kg00qf 1022 13 corneum corneum NN cord-022526-j9kg00qf 1022 14 , , , cord-022526-j9kg00qf 1022 15 stratum stratum JJ cord-022526-j9kg00qf 1022 16 transitionale transitionale NNP cord-022526-j9kg00qf 1022 17 , , , cord-022526-j9kg00qf 1022 18 stratum stratum NN cord-022526-j9kg00qf 1022 19 spinosum spinosum NNP cord-022526-j9kg00qf 1022 20 , , , cord-022526-j9kg00qf 1022 21 and and CC cord-022526-j9kg00qf 1022 22 the the DT cord-022526-j9kg00qf 1022 23 basal basal NN cord-022526-j9kg00qf 1022 24 stratum stratum NN cord-022526-j9kg00qf 1022 25 germinativum germinativum NNP cord-022526-j9kg00qf 1022 26 . . . cord-022526-j9kg00qf 1023 1 However however RB cord-022526-j9kg00qf 1023 2 , , , cord-022526-j9kg00qf 1023 3 not not RB cord-022526-j9kg00qf 1023 4 all all DT cord-022526-j9kg00qf 1023 5 layers layer NNS cord-022526-j9kg00qf 1023 6 contribute contribute VBP cord-022526-j9kg00qf 1023 7 equally equally RB cord-022526-j9kg00qf 1023 8 to to IN cord-022526-j9kg00qf 1023 9 barrier barrier NN cord-022526-j9kg00qf 1023 10 function function NN cord-022526-j9kg00qf 1023 11 , , , cord-022526-j9kg00qf 1023 12 the the DT cord-022526-j9kg00qf 1023 13 barrier barrier NN cord-022526-j9kg00qf 1023 14 being be VBG cord-022526-j9kg00qf 1023 15 composed compose VBN cord-022526-j9kg00qf 1023 16 mostly mostly RB cord-022526-j9kg00qf 1023 17 of of IN cord-022526-j9kg00qf 1023 18 interepithelial interepithelial JJ cord-022526-j9kg00qf 1023 19 tight tight JJ cord-022526-j9kg00qf 1023 20 junctions junction NNS cord-022526-j9kg00qf 1023 21 in in IN cord-022526-j9kg00qf 1023 22 the the DT cord-022526-j9kg00qf 1023 23 stratum stratum NN cord-022526-j9kg00qf 1023 24 corneum corneum NN cord-022526-j9kg00qf 1023 25 and and CC cord-022526-j9kg00qf 1023 26 mucosubstances mucosubstance NNS cord-022526-j9kg00qf 1023 27 secreted secrete VBN cord-022526-j9kg00qf 1023 28 by by IN cord-022526-j9kg00qf 1023 29 the the DT cord-022526-j9kg00qf 1023 30 stratum stratum NN cord-022526-j9kg00qf 1023 31 spinosum spinosum NN cord-022526-j9kg00qf 1023 32 . . . cord-022526-j9kg00qf 1024 1 17 17 CD cord-022526-j9kg00qf 1024 2 , , , cord-022526-j9kg00qf 1024 3 19 19 CD cord-022526-j9kg00qf 1025 1 The the DT cord-022526-j9kg00qf 1025 2 relative relative JJ cord-022526-j9kg00qf 1025 3 impermeability impermeability NN cord-022526-j9kg00qf 1025 4 of of IN cord-022526-j9kg00qf 1025 5 stratified stratified JJ cord-022526-j9kg00qf 1025 6 squamous squamous JJ cord-022526-j9kg00qf 1025 7 mucosa mucosa NN cord-022526-j9kg00qf 1025 8 can can MD cord-022526-j9kg00qf 1025 9 be be VB cord-022526-j9kg00qf 1025 10 demonstrated demonstrate VBN cord-022526-j9kg00qf 1025 11 by by IN cord-022526-j9kg00qf 1025 12 the the DT cord-022526-j9kg00qf 1025 13 effects effect NNS cord-022526-j9kg00qf 1025 14 of of IN cord-022526-j9kg00qf 1025 15 HCl hcl NN cord-022526-j9kg00qf 1025 16 on on IN cord-022526-j9kg00qf 1025 17 this this DT cord-022526-j9kg00qf 1025 18 type type NN cord-022526-j9kg00qf 1025 19 of of IN cord-022526-j9kg00qf 1025 20 epithelium epithelium NN cord-022526-j9kg00qf 1025 21 in in IN cord-022526-j9kg00qf 1025 22 vitro vitro FW cord-022526-j9kg00qf 1025 23 , , , cord-022526-j9kg00qf 1025 24 which which WDT cord-022526-j9kg00qf 1025 25 has have VBZ cord-022526-j9kg00qf 1025 26 little little JJ cord-022526-j9kg00qf 1025 27 effect effect NN cord-022526-j9kg00qf 1025 28 until until IN cord-022526-j9kg00qf 1025 29 it -PRON- PRP cord-022526-j9kg00qf 1025 30 reaches reach VBZ cord-022526-j9kg00qf 1025 31 a a DT cord-022526-j9kg00qf 1025 32 pH ph NN cord-022526-j9kg00qf 1025 33 of of IN cord-022526-j9kg00qf 1025 34 2.5 2.5 CD cord-022526-j9kg00qf 1025 35 or or CC cord-022526-j9kg00qf 1025 36 lower low JJR cord-022526-j9kg00qf 1025 37 . . . cord-022526-j9kg00qf 1026 1 18 18 CD cord-022526-j9kg00qf 1027 1 Thus thus RB cord-022526-j9kg00qf 1027 2 although although IN cord-022526-j9kg00qf 1027 3 most most JJS cord-022526-j9kg00qf 1027 4 of of IN cord-022526-j9kg00qf 1027 5 the the DT cord-022526-j9kg00qf 1027 6 literature literature NN cord-022526-j9kg00qf 1027 7 on on IN cord-022526-j9kg00qf 1027 8 equine equine JJ cord-022526-j9kg00qf 1027 9 ulceration ulceration NN cord-022526-j9kg00qf 1027 10 pertains pertain VBZ cord-022526-j9kg00qf 1027 11 to to IN cord-022526-j9kg00qf 1027 12 the the DT cord-022526-j9kg00qf 1027 13 effects effect NNS cord-022526-j9kg00qf 1027 14 of of IN cord-022526-j9kg00qf 1027 15 HCl hcl NN cord-022526-j9kg00qf 1027 16 and and CC cord-022526-j9kg00qf 1027 17 inhibitors inhibitor NNS cord-022526-j9kg00qf 1027 18 of of IN cord-022526-j9kg00qf 1027 19 HCl HCl NNP cord-022526-j9kg00qf 1027 20 secretion secretion NN cord-022526-j9kg00qf 1027 21 , , , cord-022526-j9kg00qf 1027 22 [ [ -LRB- cord-022526-j9kg00qf 1027 23 20 20 CD cord-022526-j9kg00qf 1027 24 ] ] -RRB- cord-022526-j9kg00qf 1027 25 [ [ -LRB- cord-022526-j9kg00qf 1027 26 21 21 CD cord-022526-j9kg00qf 1027 27 ] ] -RRB- cord-022526-j9kg00qf 1027 28 [ [ -LRB- cord-022526-j9kg00qf 1027 29 22 22 CD cord-022526-j9kg00qf 1027 30 ] ] -RRB- cord-022526-j9kg00qf 1027 31 [ [ -LRB- cord-022526-j9kg00qf 1027 32 23 23 CD cord-022526-j9kg00qf 1027 33 ] ] -RRB- cord-022526-j9kg00qf 1028 1 other other JJ cord-022526-j9kg00qf 1028 2 factors factor NNS cord-022526-j9kg00qf 1028 3 may may MD cord-022526-j9kg00qf 1028 4 be be VB cord-022526-j9kg00qf 1028 5 critical critical JJ cord-022526-j9kg00qf 1028 6 to to IN cord-022526-j9kg00qf 1028 7 the the DT cord-022526-j9kg00qf 1028 8 development development NN cord-022526-j9kg00qf 1028 9 of of IN cord-022526-j9kg00qf 1028 10 gastric gastric JJ cord-022526-j9kg00qf 1028 11 ulcer ulcer NN cord-022526-j9kg00qf 1028 12 disease disease NN cord-022526-j9kg00qf 1028 13 . . . cord-022526-j9kg00qf 1029 1 The the DT cord-022526-j9kg00qf 1029 2 site site NN cord-022526-j9kg00qf 1029 3 of of IN cord-022526-j9kg00qf 1029 4 HCl HCl NNP cord-022526-j9kg00qf 1029 5 secretion secretion NN cord-022526-j9kg00qf 1029 6 ( ( -LRB- cord-022526-j9kg00qf 1029 7 proper proper JJ cord-022526-j9kg00qf 1029 8 gastric gastric JJ cord-022526-j9kg00qf 1029 9 mucosa mucosa NN cord-022526-j9kg00qf 1029 10 ) ) -RRB- cord-022526-j9kg00qf 1029 11 also also RB cord-022526-j9kg00qf 1029 12 is be VBZ cord-022526-j9kg00qf 1029 13 protected protect VBN cord-022526-j9kg00qf 1029 14 from from IN cord-022526-j9kg00qf 1029 15 so so RB cord-022526-j9kg00qf 1029 16 - - HYPH cord-022526-j9kg00qf 1029 17 called call VBN cord-022526-j9kg00qf 1029 18 back back NN cord-022526-j9kg00qf 1029 19 - - HYPH cord-022526-j9kg00qf 1029 20 diffusion diffusion NN cord-022526-j9kg00qf 1029 21 of of IN cord-022526-j9kg00qf 1029 22 H H NNP cord-022526-j9kg00qf 1029 23 + + SYM cord-022526-j9kg00qf 1029 24 by by IN cord-022526-j9kg00qf 1029 25 a a DT cord-022526-j9kg00qf 1029 26 high high JJ cord-022526-j9kg00qf 1029 27 transepithelial transepithelial JJ cord-022526-j9kg00qf 1029 28 electric electric JJ cord-022526-j9kg00qf 1029 29 resistance resistance NN cord-022526-j9kg00qf 1029 30 ( ( -LRB- cord-022526-j9kg00qf 1029 31 compared compare VBN cord-022526-j9kg00qf 1029 32 with with IN cord-022526-j9kg00qf 1029 33 cardiac cardiac JJ cord-022526-j9kg00qf 1029 34 mucosa mucosa NN cord-022526-j9kg00qf 1029 35 ) ) -RRB- cord-022526-j9kg00qf 1029 36 , , , cord-022526-j9kg00qf 1029 37 but but CC cord-022526-j9kg00qf 1029 38 a a DT cord-022526-j9kg00qf 1029 39 number number NN cord-022526-j9kg00qf 1029 40 of of IN cord-022526-j9kg00qf 1029 41 other other JJ cord-022526-j9kg00qf 1029 42 critical critical JJ cord-022526-j9kg00qf 1029 43 mechanisms mechanism NNS cord-022526-j9kg00qf 1029 44 also also RB cord-022526-j9kg00qf 1029 45 exist exist VBP cord-022526-j9kg00qf 1029 46 to to TO cord-022526-j9kg00qf 1029 47 prevent prevent VB cord-022526-j9kg00qf 1029 48 acid acid NN cord-022526-j9kg00qf 1029 49 injury injury NN cord-022526-j9kg00qf 1029 50 . . . cord-022526-j9kg00qf 1030 1 The the DT cord-022526-j9kg00qf 1030 2 gastric gastric JJ cord-022526-j9kg00qf 1030 3 mucosa mucosa NN cord-022526-j9kg00qf 1030 4 secretes secrete VBZ cord-022526-j9kg00qf 1030 5 mucus mucus NN cord-022526-j9kg00qf 1030 6 and and CC cord-022526-j9kg00qf 1030 7 bicarbonate bicarbonate NN cord-022526-j9kg00qf 1030 8 , , , cord-022526-j9kg00qf 1030 9 which which WDT cord-022526-j9kg00qf 1030 10 together together RB cord-022526-j9kg00qf 1030 11 form form VBP cord-022526-j9kg00qf 1030 12 a a DT cord-022526-j9kg00qf 1030 13 HCO HCO NNP cord-022526-j9kg00qf 1030 14 3 3 CD cord-022526-j9kg00qf 1030 15 --containing --containing NN cord-022526-j9kg00qf 1030 16 gel gel NN cord-022526-j9kg00qf 1030 17 that that WDT cord-022526-j9kg00qf 1030 18 titrates titrate VBZ cord-022526-j9kg00qf 1030 19 acid acid NN cord-022526-j9kg00qf 1030 20 before before IN cord-022526-j9kg00qf 1030 21 it -PRON- PRP cord-022526-j9kg00qf 1030 22 reaches reach VBZ cord-022526-j9kg00qf 1030 23 the the DT cord-022526-j9kg00qf 1030 24 lumen lumen NN cord-022526-j9kg00qf 1030 25 . . . cord-022526-j9kg00qf 1031 1 24 24 CD cord-022526-j9kg00qf 1031 2 , , , cord-022526-j9kg00qf 1031 3 25 25 CD cord-022526-j9kg00qf 1031 4 The the DT cord-022526-j9kg00qf 1031 5 mucus mucus NN cord-022526-j9kg00qf 1031 6 layer layer NN cord-022526-j9kg00qf 1031 7 is be VBZ cord-022526-j9kg00qf 1031 8 formed form VBN cord-022526-j9kg00qf 1031 9 principally principally RB cord-022526-j9kg00qf 1031 10 by by IN cord-022526-j9kg00qf 1031 11 glycoproteins glycoprotein NNS cord-022526-j9kg00qf 1031 12 ( ( -LRB- cord-022526-j9kg00qf 1031 13 mucins mucins NNP cord-022526-j9kg00qf 1031 14 ) ) -RRB- cord-022526-j9kg00qf 1031 15 secreted secrete VBN cord-022526-j9kg00qf 1031 16 by by IN cord-022526-j9kg00qf 1031 17 goblet goblet NN cord-022526-j9kg00qf 1031 18 cells cell NNS cord-022526-j9kg00qf 1031 19 but but CC cord-022526-j9kg00qf 1031 20 also also RB cord-022526-j9kg00qf 1031 21 includes include VBZ cord-022526-j9kg00qf 1031 22 other other JJ cord-022526-j9kg00qf 1031 23 gastric gastric JJ cord-022526-j9kg00qf 1031 24 secretions secretion NNS cord-022526-j9kg00qf 1031 25 and and CC cord-022526-j9kg00qf 1031 26 sloughed slough VBD cord-022526-j9kg00qf 1031 27 epithelial epithelial JJ cord-022526-j9kg00qf 1031 28 cells cell NNS cord-022526-j9kg00qf 1031 29 . . . cord-022526-j9kg00qf 1032 1 Mucins mucin NNS cord-022526-j9kg00qf 1032 2 consist consist VBP cord-022526-j9kg00qf 1032 3 of of IN cord-022526-j9kg00qf 1032 4 core core NN cord-022526-j9kg00qf 1032 5 peptides peptide NNS cord-022526-j9kg00qf 1032 6 with with IN cord-022526-j9kg00qf 1032 7 a a DT cord-022526-j9kg00qf 1032 8 series series NN cord-022526-j9kg00qf 1032 9 of of IN cord-022526-j9kg00qf 1032 10 densely densely RB cord-022526-j9kg00qf 1032 11 packed pack VBN cord-022526-j9kg00qf 1032 12 O o NN cord-022526-j9kg00qf 1032 13 - - HYPH cord-022526-j9kg00qf 1032 14 linked link VBN cord-022526-j9kg00qf 1032 15 polysaccharide polysaccharide NN cord-022526-j9kg00qf 1032 16 side side NN cord-022526-j9kg00qf 1032 17 chains chain NNS cord-022526-j9kg00qf 1032 18 that that WDT cord-022526-j9kg00qf 1032 19 , , , cord-022526-j9kg00qf 1032 20 once once RB cord-022526-j9kg00qf 1032 21 secreted secrete VBN cord-022526-j9kg00qf 1032 22 , , , cord-022526-j9kg00qf 1032 23 become become VBP cord-022526-j9kg00qf 1032 24 hydrated hydrated JJ cord-022526-j9kg00qf 1032 25 and and CC cord-022526-j9kg00qf 1032 26 form form VB cord-022526-j9kg00qf 1032 27 a a DT cord-022526-j9kg00qf 1032 28 viscoelastic viscoelastic JJ cord-022526-j9kg00qf 1032 29 gel gel NN cord-022526-j9kg00qf 1032 30 . . . cord-022526-j9kg00qf 1033 1 However however RB cord-022526-j9kg00qf 1033 2 , , , cord-022526-j9kg00qf 1033 3 the the DT cord-022526-j9kg00qf 1033 4 mucus mucus NN cord-022526-j9kg00qf 1033 5 layer layer NN cord-022526-j9kg00qf 1033 6 does do VBZ cord-022526-j9kg00qf 1033 7 not not RB cord-022526-j9kg00qf 1033 8 form form VB cord-022526-j9kg00qf 1033 9 an an DT cord-022526-j9kg00qf 1033 10 absolute absolute JJ cord-022526-j9kg00qf 1033 11 barrier barrier NN cord-022526-j9kg00qf 1033 12 to to IN cord-022526-j9kg00qf 1033 13 back back NN cord-022526-j9kg00qf 1033 14 - - HYPH cord-022526-j9kg00qf 1033 15 diffusion diffusion NN cord-022526-j9kg00qf 1033 16 of of IN cord-022526-j9kg00qf 1033 17 acid acid NN cord-022526-j9kg00qf 1033 18 . . . cord-022526-j9kg00qf 1034 1 Thus thus RB cord-022526-j9kg00qf 1034 2 for for IN cord-022526-j9kg00qf 1034 3 acid acid NN cord-022526-j9kg00qf 1034 4 that that WDT cord-022526-j9kg00qf 1034 5 does do VBZ cord-022526-j9kg00qf 1034 6 back back RB cord-022526-j9kg00qf 1034 7 - - HYPH cord-022526-j9kg00qf 1034 8 diffuse diffuse NN cord-022526-j9kg00qf 1034 9 into into IN cord-022526-j9kg00qf 1034 10 the the DT cord-022526-j9kg00qf 1034 11 gastric gastric JJ cord-022526-j9kg00qf 1034 12 mucosa mucosa NN cord-022526-j9kg00qf 1034 13 , , . cord-022526-j9kg00qf 1035 1 epithelial epithelial JJ cord-022526-j9kg00qf 1035 2 Na Na NNP cord-022526-j9kg00qf 1035 3 + + CC cord-022526-j9kg00qf 1036 1 /H /H NNP cord-022526-j9kg00qf 1036 2 + + CC cord-022526-j9kg00qf 1036 3 exchangers exchanger NNS cord-022526-j9kg00qf 1036 4 are be VBP cord-022526-j9kg00qf 1036 5 capable capable JJ cord-022526-j9kg00qf 1036 6 of of IN cord-022526-j9kg00qf 1036 7 expelling expel VBG cord-022526-j9kg00qf 1036 8 H h NN cord-022526-j9kg00qf 1036 9 + + CC cord-022526-j9kg00qf 1036 10 once once IN cord-022526-j9kg00qf 1036 11 the the DT cord-022526-j9kg00qf 1036 12 cell cell NN cord-022526-j9kg00qf 1036 13 reaches reach VBZ cord-022526-j9kg00qf 1036 14 a a DT cord-022526-j9kg00qf 1036 15 critical critical JJ cord-022526-j9kg00qf 1036 16 pH. ph. NN cord-022526-j9kg00qf 1036 17 25 25 CD cord-022526-j9kg00qf 1036 18 Recent recent JJ cord-022526-j9kg00qf 1036 19 studies study NNS cord-022526-j9kg00qf 1036 20 have have VBP cord-022526-j9kg00qf 1036 21 renewed renew VBN cord-022526-j9kg00qf 1036 22 interest interest NN cord-022526-j9kg00qf 1036 23 in in IN cord-022526-j9kg00qf 1036 24 the the DT cord-022526-j9kg00qf 1036 25 protective protective JJ cord-022526-j9kg00qf 1036 26 mechanisms mechanism NNS cord-022526-j9kg00qf 1036 27 of of IN cord-022526-j9kg00qf 1036 28 mucus mucus NN cord-022526-j9kg00qf 1036 29 because because IN cord-022526-j9kg00qf 1036 30 of of IN cord-022526-j9kg00qf 1036 31 the the DT cord-022526-j9kg00qf 1036 32 discovery discovery NN cord-022526-j9kg00qf 1036 33 of of IN cord-022526-j9kg00qf 1036 34 a a DT cord-022526-j9kg00qf 1036 35 group group NN cord-022526-j9kg00qf 1036 36 of of IN cord-022526-j9kg00qf 1036 37 compounds compound NNS cord-022526-j9kg00qf 1036 38 secreted secrete VBN cord-022526-j9kg00qf 1036 39 by by IN cord-022526-j9kg00qf 1036 40 goblet goblet NN cord-022526-j9kg00qf 1036 41 cells cell NNS cord-022526-j9kg00qf 1036 42 called call VBN cord-022526-j9kg00qf 1036 43 trefoil trefoil NN cord-022526-j9kg00qf 1036 44 peptides peptide NNS cord-022526-j9kg00qf 1036 45 . . . cord-022526-j9kg00qf 1037 1 The the DT cord-022526-j9kg00qf 1037 2 name name NN cord-022526-j9kg00qf 1037 3 of of IN cord-022526-j9kg00qf 1037 4 these these DT cord-022526-j9kg00qf 1037 5 peptides peptide NNS cord-022526-j9kg00qf 1037 6 is be VBZ cord-022526-j9kg00qf 1037 7 derived derive VBN cord-022526-j9kg00qf 1037 8 from from IN cord-022526-j9kg00qf 1037 9 a a DT cord-022526-j9kg00qf 1037 10 highly highly RB cord-022526-j9kg00qf 1037 11 conserved conserve VBN cord-022526-j9kg00qf 1037 12 cloverleaf cloverleaf JJ cord-022526-j9kg00qf 1037 13 structural structural JJ cord-022526-j9kg00qf 1037 14 motif motif NN cord-022526-j9kg00qf 1037 15 , , , cord-022526-j9kg00qf 1037 16 which which WDT cord-022526-j9kg00qf 1037 17 confers confer VBZ cord-022526-j9kg00qf 1037 18 substantial substantial JJ cord-022526-j9kg00qf 1037 19 resistance resistance NN cord-022526-j9kg00qf 1037 20 to to IN cord-022526-j9kg00qf 1037 21 degradation degradation NN cord-022526-j9kg00qf 1037 22 by by IN cord-022526-j9kg00qf 1037 23 proteases protease NNS cord-022526-j9kg00qf 1037 24 including include VBG cord-022526-j9kg00qf 1037 25 pepsin pepsin NN cord-022526-j9kg00qf 1037 26 . . . cord-022526-j9kg00qf 1038 1 Three three CD cord-022526-j9kg00qf 1038 2 members member NNS cord-022526-j9kg00qf 1038 3 of of IN cord-022526-j9kg00qf 1038 4 this this DT cord-022526-j9kg00qf 1038 5 group group NN cord-022526-j9kg00qf 1038 6 are be VBP cord-022526-j9kg00qf 1038 7 known know VBN cord-022526-j9kg00qf 1038 8 , , , cord-022526-j9kg00qf 1038 9 pS2 ps2 JJ cord-022526-j9kg00qf 1038 10 , , , cord-022526-j9kg00qf 1038 11 SP SP NNP cord-022526-j9kg00qf 1038 12 , , , cord-022526-j9kg00qf 1038 13 and and CC cord-022526-j9kg00qf 1038 14 intestinal intestinal JJ cord-022526-j9kg00qf 1038 15 trefoil trefoil NN cord-022526-j9kg00qf 1038 16 factor factor NN cord-022526-j9kg00qf 1038 17 , , , cord-022526-j9kg00qf 1038 18 the the DT cord-022526-j9kg00qf 1038 19 latter latter JJ cord-022526-j9kg00qf 1038 20 of of IN cord-022526-j9kg00qf 1038 21 which which WDT cord-022526-j9kg00qf 1038 22 is be VBZ cord-022526-j9kg00qf 1038 23 secreted secrete VBN cord-022526-j9kg00qf 1038 24 solely solely RB cord-022526-j9kg00qf 1038 25 by by IN cord-022526-j9kg00qf 1038 26 goblet goblet NN cord-022526-j9kg00qf 1038 27 cells cell NNS cord-022526-j9kg00qf 1038 28 in in IN cord-022526-j9kg00qf 1038 29 the the DT cord-022526-j9kg00qf 1038 30 small small JJ cord-022526-j9kg00qf 1038 31 and and CC cord-022526-j9kg00qf 1038 32 large large JJ cord-022526-j9kg00qf 1038 33 intestine intestine NN cord-022526-j9kg00qf 1038 34 . . . cord-022526-j9kg00qf 1039 1 pS2 pS2 NNP cord-022526-j9kg00qf 1039 2 and and CC cord-022526-j9kg00qf 1039 3 SP SP NNP cord-022526-j9kg00qf 1039 4 are be VBP cord-022526-j9kg00qf 1039 5 secreted secrete VBN cord-022526-j9kg00qf 1039 6 by by IN cord-022526-j9kg00qf 1039 7 goblet goblet NN cord-022526-j9kg00qf 1039 8 cells cell NNS cord-022526-j9kg00qf 1039 9 within within IN cord-022526-j9kg00qf 1039 10 the the DT cord-022526-j9kg00qf 1039 11 stomach stomach NN cord-022526-j9kg00qf 1039 12 and and CC cord-022526-j9kg00qf 1039 13 are be VBP cord-022526-j9kg00qf 1039 14 believed believe VBN cord-022526-j9kg00qf 1039 15 to to TO cord-022526-j9kg00qf 1039 16 intercalate intercalate VB cord-022526-j9kg00qf 1039 17 with with IN cord-022526-j9kg00qf 1039 18 mucus mucus NN cord-022526-j9kg00qf 1039 19 glycoproteins glycoprotein NNS cord-022526-j9kg00qf 1039 20 , , , cord-022526-j9kg00qf 1039 21 possibly possibly RB cord-022526-j9kg00qf 1039 22 contributing contribute VBG cord-022526-j9kg00qf 1039 23 to to IN cord-022526-j9kg00qf 1039 24 the the DT cord-022526-j9kg00qf 1039 25 barrier barrier NN cord-022526-j9kg00qf 1039 26 properties property NNS cord-022526-j9kg00qf 1039 27 of of IN cord-022526-j9kg00qf 1039 28 mucus mucus NN cord-022526-j9kg00qf 1039 29 . . . cord-022526-j9kg00qf 1040 1 26 26 CD cord-022526-j9kg00qf 1041 1 These these DT cord-022526-j9kg00qf 1041 2 peptides peptide NNS cord-022526-j9kg00qf 1041 3 also also RB cord-022526-j9kg00qf 1041 4 play play VBP cord-022526-j9kg00qf 1041 5 a a DT cord-022526-j9kg00qf 1041 6 critical critical JJ cord-022526-j9kg00qf 1041 7 role role NN cord-022526-j9kg00qf 1041 8 in in IN cord-022526-j9kg00qf 1041 9 repair repair NN cord-022526-j9kg00qf 1041 10 of of IN cord-022526-j9kg00qf 1041 11 injured injured JJ cord-022526-j9kg00qf 1041 12 mucosa mucosa NN cord-022526-j9kg00qf 1041 13 . . . cord-022526-j9kg00qf 1042 1 An an DT cord-022526-j9kg00qf 1042 2 additional additional JJ cord-022526-j9kg00qf 1042 3 mucosal mucosal JJ cord-022526-j9kg00qf 1042 4 function function NN cord-022526-j9kg00qf 1042 5 that that WDT cord-022526-j9kg00qf 1042 6 serves serve VBZ cord-022526-j9kg00qf 1042 7 to to TO cord-022526-j9kg00qf 1042 8 reduce reduce VB cord-022526-j9kg00qf 1042 9 the the DT cord-022526-j9kg00qf 1042 10 level level NN cord-022526-j9kg00qf 1042 11 of of IN cord-022526-j9kg00qf 1042 12 injury injury NN cord-022526-j9kg00qf 1042 13 is be VBZ cord-022526-j9kg00qf 1042 14 adaptive adaptive JJ cord-022526-j9kg00qf 1042 15 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1042 16 , , , cord-022526-j9kg00qf 1042 17 wherein wherein WRB cord-022526-j9kg00qf 1042 18 application application NN cord-022526-j9kg00qf 1042 19 of of IN cord-022526-j9kg00qf 1042 20 topical topical JJ cord-022526-j9kg00qf 1042 21 irritants irritant NNS cord-022526-j9kg00qf 1042 22 to to IN cord-022526-j9kg00qf 1042 23 gastric gastric JJ cord-022526-j9kg00qf 1042 24 mucosa mucosa JJ cord-022526-j9kg00qf 1042 25 results result NNS cord-022526-j9kg00qf 1042 26 in in IN cord-022526-j9kg00qf 1042 27 subsequent subsequent JJ cord-022526-j9kg00qf 1042 28 protection protection NN cord-022526-j9kg00qf 1042 29 of of IN cord-022526-j9kg00qf 1042 30 mucosa mucosa NN cord-022526-j9kg00qf 1042 31 in in IN cord-022526-j9kg00qf 1042 32 response response NN cord-022526-j9kg00qf 1042 33 to to IN cord-022526-j9kg00qf 1042 34 repeated repeat VBN cord-022526-j9kg00qf 1042 35 exposure exposure NN cord-022526-j9kg00qf 1042 36 to to IN cord-022526-j9kg00qf 1042 37 damaging damaging JJ cord-022526-j9kg00qf 1042 38 agents agent NNS cord-022526-j9kg00qf 1042 39 . . . cord-022526-j9kg00qf 1043 1 For for IN cord-022526-j9kg00qf 1043 2 example example NN cord-022526-j9kg00qf 1043 3 , , , cord-022526-j9kg00qf 1043 4 pretreatment pretreatment NN cord-022526-j9kg00qf 1043 5 with with IN cord-022526-j9kg00qf 1043 6 10 10 CD cord-022526-j9kg00qf 1043 7 % % NN cord-022526-j9kg00qf 1043 8 ethanol ethanol NN cord-022526-j9kg00qf 1043 9 protected protect VBN cord-022526-j9kg00qf 1043 10 against against IN cord-022526-j9kg00qf 1043 11 mucosal mucosal JJ cord-022526-j9kg00qf 1043 12 damage damage NN cord-022526-j9kg00qf 1043 13 in in IN cord-022526-j9kg00qf 1043 14 response response NN cord-022526-j9kg00qf 1043 15 to to IN cord-022526-j9kg00qf 1043 16 subsequent subsequent JJ cord-022526-j9kg00qf 1043 17 application application NN cord-022526-j9kg00qf 1043 18 of of IN cord-022526-j9kg00qf 1043 19 absolute absolute JJ cord-022526-j9kg00qf 1043 20 ethanol ethanol NN cord-022526-j9kg00qf 1043 21 , , , cord-022526-j9kg00qf 1043 22 and and CC cord-022526-j9kg00qf 1043 23 this this DT cord-022526-j9kg00qf 1043 24 effect effect NN cord-022526-j9kg00qf 1043 25 was be VBD cord-022526-j9kg00qf 1043 26 abolished abolish VBN cord-022526-j9kg00qf 1043 27 by by IN cord-022526-j9kg00qf 1043 28 treatment treatment NN cord-022526-j9kg00qf 1043 29 with with IN cord-022526-j9kg00qf 1043 30 the the DT cord-022526-j9kg00qf 1043 31 cyclooxygenase cyclooxygenase JJ cord-022526-j9kg00qf 1043 32 inhibitor inhibitor NN cord-022526-j9kg00qf 1043 33 indomethacin indomethacin NN cord-022526-j9kg00qf 1043 34 . . . cord-022526-j9kg00qf 1044 1 27 27 CD cord-022526-j9kg00qf 1045 1 The the DT cord-022526-j9kg00qf 1045 2 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1045 3 effect effect NN cord-022526-j9kg00qf 1045 4 of of IN cord-022526-j9kg00qf 1045 5 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1045 6 has have VBZ cord-022526-j9kg00qf 1045 7 been be VBN cord-022526-j9kg00qf 1045 8 demonstrated demonstrate VBN cord-022526-j9kg00qf 1045 9 directly directly RB cord-022526-j9kg00qf 1045 10 in in IN cord-022526-j9kg00qf 1045 11 studies study NNS cord-022526-j9kg00qf 1045 12 in in IN cord-022526-j9kg00qf 1045 13 which which WDT cord-022526-j9kg00qf 1045 14 preadministration preadministration NN cord-022526-j9kg00qf 1045 15 of of IN cord-022526-j9kg00qf 1045 16 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1045 17 protected protect VBD cord-022526-j9kg00qf 1045 18 gastric gastric JJ cord-022526-j9kg00qf 1045 19 mucosa mucosa NN cord-022526-j9kg00qf 1045 20 from from IN cord-022526-j9kg00qf 1045 21 damage damage NN cord-022526-j9kg00qf 1045 22 by by IN cord-022526-j9kg00qf 1045 23 agents agent NNS cord-022526-j9kg00qf 1045 24 such such JJ cord-022526-j9kg00qf 1045 25 as as IN cord-022526-j9kg00qf 1045 26 concentrated concentrated JJ cord-022526-j9kg00qf 1045 27 HCl hcl NN cord-022526-j9kg00qf 1045 28 and and CC cord-022526-j9kg00qf 1045 29 hypertonic hypertonic JJ cord-022526-j9kg00qf 1045 30 saline saline NN cord-022526-j9kg00qf 1045 31 . . . cord-022526-j9kg00qf 1046 1 28 28 CD cord-022526-j9kg00qf 1046 2 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1046 3 appear appear VBP cord-022526-j9kg00qf 1046 4 to to TO cord-022526-j9kg00qf 1046 5 be be VB cord-022526-j9kg00qf 1046 6 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1046 7 in in IN cord-022526-j9kg00qf 1046 8 the the DT cord-022526-j9kg00qf 1046 9 stomach stomach NN cord-022526-j9kg00qf 1046 10 at at IN cord-022526-j9kg00qf 1046 11 doses dose NNS cord-022526-j9kg00qf 1046 12 less less JJR cord-022526-j9kg00qf 1046 13 than than IN cord-022526-j9kg00qf 1046 14 those those DT cord-022526-j9kg00qf 1046 15 used use VBN cord-022526-j9kg00qf 1046 16 to to TO cord-022526-j9kg00qf 1046 17 inhibit inhibit VB cord-022526-j9kg00qf 1046 18 gastric gastric JJ cord-022526-j9kg00qf 1046 19 acid acid NN cord-022526-j9kg00qf 1046 20 secretion secretion NN cord-022526-j9kg00qf 1046 21 , , , cord-022526-j9kg00qf 1046 22 ruling rule VBG cord-022526-j9kg00qf 1046 23 out out RP cord-022526-j9kg00qf 1046 24 a a DT cord-022526-j9kg00qf 1046 25 simple simple JJ cord-022526-j9kg00qf 1046 26 antacid antacid NN cord-022526-j9kg00qf 1046 27 mechanism mechanism NN cord-022526-j9kg00qf 1046 28 . . . cord-022526-j9kg00qf 1047 1 29 29 CD cord-022526-j9kg00qf 1048 1 Although although IN cord-022526-j9kg00qf 1048 2 not not RB cord-022526-j9kg00qf 1048 3 fully fully RB cord-022526-j9kg00qf 1048 4 characterized characterize VBN cord-022526-j9kg00qf 1048 5 , , , cord-022526-j9kg00qf 1048 6 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1048 7 has have VBZ cord-022526-j9kg00qf 1048 8 been be VBN cord-022526-j9kg00qf 1048 9 attributed attribute VBN cord-022526-j9kg00qf 1048 10 in in IN cord-022526-j9kg00qf 1048 11 part part NN cord-022526-j9kg00qf 1048 12 to to IN cord-022526-j9kg00qf 1048 13 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1048 14 - - HYPH cord-022526-j9kg00qf 1048 15 stimulated stimulate VBN cord-022526-j9kg00qf 1048 16 mucus mucus NN cord-022526-j9kg00qf 1048 17 production production NN cord-022526-j9kg00qf 1048 18 . . . cord-022526-j9kg00qf 1049 1 30 30 CD cord-022526-j9kg00qf 1050 1 An an DT cord-022526-j9kg00qf 1050 2 associated associated JJ cord-022526-j9kg00qf 1050 3 beneficial beneficial JJ cord-022526-j9kg00qf 1050 4 effect effect NN cord-022526-j9kg00qf 1050 5 of of IN cord-022526-j9kg00qf 1050 6 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1050 7 is be VBZ cord-022526-j9kg00qf 1050 8 the the DT cord-022526-j9kg00qf 1050 9 increased increase VBN cord-022526-j9kg00qf 1050 10 production production NN cord-022526-j9kg00qf 1050 11 of of IN cord-022526-j9kg00qf 1050 12 bicarbonate bicarbonate NN cord-022526-j9kg00qf 1050 13 , , , cord-022526-j9kg00qf 1050 14 which which WDT cord-022526-j9kg00qf 1050 15 is be VBZ cord-022526-j9kg00qf 1050 16 trapped trap VBN cord-022526-j9kg00qf 1050 17 within within IN cord-022526-j9kg00qf 1050 18 mucus mucus NN cord-022526-j9kg00qf 1050 19 on on IN cord-022526-j9kg00qf 1050 20 the the DT cord-022526-j9kg00qf 1050 21 surface surface NN cord-022526-j9kg00qf 1050 22 of of IN cord-022526-j9kg00qf 1050 23 the the DT cord-022526-j9kg00qf 1050 24 mucosa mucosa NN cord-022526-j9kg00qf 1050 25 . . . cord-022526-j9kg00qf 1051 1 31 31 CD cord-022526-j9kg00qf 1051 2 , , , cord-022526-j9kg00qf 1051 3 32 32 CD cord-022526-j9kg00qf 1052 1 Interestingly interestingly RB cord-022526-j9kg00qf 1052 2 , , , cord-022526-j9kg00qf 1052 3 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1052 4 E e NN cord-022526-j9kg00qf 1052 5 2 2 CD cord-022526-j9kg00qf 1052 6 ( ( -LRB- cord-022526-j9kg00qf 1052 7 PGE PGE NNP cord-022526-j9kg00qf 1052 8 2 2 CD cord-022526-j9kg00qf 1052 9 ) ) -RRB- cord-022526-j9kg00qf 1052 10 appears appear VBZ cord-022526-j9kg00qf 1052 11 to to TO cord-022526-j9kg00qf 1052 12 lose lose VB cord-022526-j9kg00qf 1052 13 its -PRON- PRP$ cord-022526-j9kg00qf 1052 14 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1052 15 activity activity NN cord-022526-j9kg00qf 1052 16 in in IN cord-022526-j9kg00qf 1052 17 the the DT cord-022526-j9kg00qf 1052 18 presence presence NN cord-022526-j9kg00qf 1052 19 of of IN cord-022526-j9kg00qf 1052 20 the the DT cord-022526-j9kg00qf 1052 21 mucolytic mucolytic JJ cord-022526-j9kg00qf 1052 22 agent agent NN cord-022526-j9kg00qf 1052 23 N N NNP cord-022526-j9kg00qf 1052 24 - - HYPH cord-022526-j9kg00qf 1052 25 acetylcysteine acetylcysteine NN cord-022526-j9kg00qf 1052 26 . . . cord-022526-j9kg00qf 1053 1 Attention attention NN cord-022526-j9kg00qf 1053 2 also also RB cord-022526-j9kg00qf 1053 3 has have VBZ cord-022526-j9kg00qf 1053 4 been be VBN cord-022526-j9kg00qf 1053 5 directed direct VBN cord-022526-j9kg00qf 1053 6 at at IN cord-022526-j9kg00qf 1053 7 enhanced enhance VBN cord-022526-j9kg00qf 1053 8 mucosal mucosal JJ cord-022526-j9kg00qf 1053 9 blood blood NN cord-022526-j9kg00qf 1053 10 flow flow NN cord-022526-j9kg00qf 1053 11 as as IN cord-022526-j9kg00qf 1053 12 a a DT cord-022526-j9kg00qf 1053 13 potential potential JJ cord-022526-j9kg00qf 1053 14 mechanism mechanism NN cord-022526-j9kg00qf 1053 15 for for IN cord-022526-j9kg00qf 1053 16 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1053 17 - - HYPH cord-022526-j9kg00qf 1053 18 mediated mediate VBN cord-022526-j9kg00qf 1053 19 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1053 20 . . . cord-022526-j9kg00qf 1054 1 For for IN cord-022526-j9kg00qf 1054 2 example example NN cord-022526-j9kg00qf 1054 3 , , , cord-022526-j9kg00qf 1054 4 pretreatment pretreatment NN cord-022526-j9kg00qf 1054 5 with with IN cord-022526-j9kg00qf 1054 6 PGI PGI NNP cord-022526-j9kg00qf 1054 7 2 2 CD cord-022526-j9kg00qf 1054 8 protected protect VBN cord-022526-j9kg00qf 1054 9 against against IN cord-022526-j9kg00qf 1054 10 ethanol ethanol NN cord-022526-j9kg00qf 1054 11 - - HYPH cord-022526-j9kg00qf 1054 12 induced induce VBN cord-022526-j9kg00qf 1054 13 mucosal mucosal JJ cord-022526-j9kg00qf 1054 14 damage damage NN cord-022526-j9kg00qf 1054 15 as as IN cord-022526-j9kg00qf 1054 16 a a DT cord-022526-j9kg00qf 1054 17 result result NN cord-022526-j9kg00qf 1054 18 of of IN cord-022526-j9kg00qf 1054 19 increased increase VBN cord-022526-j9kg00qf 1054 20 mucosal mucosal JJ cord-022526-j9kg00qf 1054 21 blood blood NN cord-022526-j9kg00qf 1054 22 flow flow NN cord-022526-j9kg00qf 1054 23 . . . cord-022526-j9kg00qf 1055 1 33 33 CD cord-022526-j9kg00qf 1056 1 Although although IN cord-022526-j9kg00qf 1056 2 PGE PGE NNP cord-022526-j9kg00qf 1056 3 2 2 CD cord-022526-j9kg00qf 1056 4 , , , cord-022526-j9kg00qf 1056 5 which which WDT cord-022526-j9kg00qf 1056 6 is be VBZ cord-022526-j9kg00qf 1056 7 also also RB cord-022526-j9kg00qf 1056 8 cytoprotective cytoprotective NNP cord-022526-j9kg00qf 1056 9 , , , cord-022526-j9kg00qf 1056 10 does do VBZ cord-022526-j9kg00qf 1056 11 not not RB cord-022526-j9kg00qf 1056 12 increase increase VB cord-022526-j9kg00qf 1056 13 blood blood NN cord-022526-j9kg00qf 1056 14 flow flow NN cord-022526-j9kg00qf 1056 15 , , , cord-022526-j9kg00qf 1056 16 34 34 CD cord-022526-j9kg00qf 1056 17 it -PRON- PRP cord-022526-j9kg00qf 1056 18 may may MD cord-022526-j9kg00qf 1056 19 prevent prevent VB cord-022526-j9kg00qf 1056 20 vascular vascular JJ cord-022526-j9kg00qf 1056 21 stasis stasis NN cord-022526-j9kg00qf 1056 22 associated associate VBN cord-022526-j9kg00qf 1056 23 with with IN cord-022526-j9kg00qf 1056 24 irritant irritant NN cord-022526-j9kg00qf 1056 25 - - HYPH cord-022526-j9kg00qf 1056 26 induced induce VBN cord-022526-j9kg00qf 1056 27 vascular vascular JJ cord-022526-j9kg00qf 1056 28 damage damage NN cord-022526-j9kg00qf 1056 29 resulting result VBG cord-022526-j9kg00qf 1056 30 from from IN cord-022526-j9kg00qf 1056 31 inhibition inhibition NN cord-022526-j9kg00qf 1056 32 of of IN cord-022526-j9kg00qf 1056 33 neutrophil neutrophil NN cord-022526-j9kg00qf 1056 34 adherence adherence NN cord-022526-j9kg00qf 1056 35 to to IN cord-022526-j9kg00qf 1056 36 damaged damage VBN cord-022526-j9kg00qf 1056 37 endothelium endothelium NN cord-022526-j9kg00qf 1056 38 . . . cord-022526-j9kg00qf 1057 1 35 35 CD cord-022526-j9kg00qf 1057 2 Sensory sensory JJ cord-022526-j9kg00qf 1057 3 nerves nerve NNS cord-022526-j9kg00qf 1057 4 also also RB cord-022526-j9kg00qf 1057 5 have have VBP cord-022526-j9kg00qf 1057 6 been be VBN cord-022526-j9kg00qf 1057 7 implicated implicate VBN cord-022526-j9kg00qf 1057 8 in in IN cord-022526-j9kg00qf 1057 9 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1057 10 mechanisms mechanism NNS cord-022526-j9kg00qf 1057 11 . . . cord-022526-j9kg00qf 1058 1 These these DT cord-022526-j9kg00qf 1058 2 nerves nerve NNS cord-022526-j9kg00qf 1058 3 are be VBP cord-022526-j9kg00qf 1058 4 distributed distribute VBN cord-022526-j9kg00qf 1058 5 throughout throughout IN cord-022526-j9kg00qf 1058 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1058 7 mucosa mucosa NN cord-022526-j9kg00qf 1058 8 . . . cord-022526-j9kg00qf 1059 1 As as IN cord-022526-j9kg00qf 1059 2 an an DT cord-022526-j9kg00qf 1059 3 example example NN cord-022526-j9kg00qf 1059 4 of of IN cord-022526-j9kg00qf 1059 5 their -PRON- PRP$ cord-022526-j9kg00qf 1059 6 importance importance NN cord-022526-j9kg00qf 1059 7 in in IN cord-022526-j9kg00qf 1059 8 mucosal mucosal JJ cord-022526-j9kg00qf 1059 9 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1059 10 , , , cord-022526-j9kg00qf 1059 11 pretreatment pretreatment NN cord-022526-j9kg00qf 1059 12 of of IN cord-022526-j9kg00qf 1059 13 newborn newborn JJ cord-022526-j9kg00qf 1059 14 rats rat NNS cord-022526-j9kg00qf 1059 15 with with IN cord-022526-j9kg00qf 1059 16 capsaicin capsaicin NN cord-022526-j9kg00qf 1059 17 ( ( -LRB- cord-022526-j9kg00qf 1059 18 to to IN cord-022526-j9kg00qf 1059 19 which which WDT cord-022526-j9kg00qf 1059 20 sensory sensory JJ cord-022526-j9kg00qf 1059 21 nerves nerve NNS cord-022526-j9kg00qf 1059 22 are be VBP cord-022526-j9kg00qf 1059 23 sensitive sensitive JJ cord-022526-j9kg00qf 1059 24 ) ) -RRB- cord-022526-j9kg00qf 1059 25 renders render VBZ cord-022526-j9kg00qf 1059 26 the the DT cord-022526-j9kg00qf 1059 27 mature mature JJ cord-022526-j9kg00qf 1059 28 rats rat NNS cord-022526-j9kg00qf 1059 29 more more RBR cord-022526-j9kg00qf 1059 30 susceptible susceptible JJ cord-022526-j9kg00qf 1059 31 to to IN cord-022526-j9kg00qf 1059 32 gastric gastric JJ cord-022526-j9kg00qf 1059 33 injury injury NN cord-022526-j9kg00qf 1059 34 . . . cord-022526-j9kg00qf 1060 1 36 36 CD cord-022526-j9kg00qf 1061 1 Alternatively alternatively RB cord-022526-j9kg00qf 1061 2 , , , cord-022526-j9kg00qf 1061 3 use use NN cord-022526-j9kg00qf 1061 4 of of IN cord-022526-j9kg00qf 1061 5 a a DT cord-022526-j9kg00qf 1061 6 low low JJ cord-022526-j9kg00qf 1061 7 dose dose NN cord-022526-j9kg00qf 1061 8 of of IN cord-022526-j9kg00qf 1061 9 capsaicin capsaicin NN cord-022526-j9kg00qf 1061 10 , , , cord-022526-j9kg00qf 1061 11 which which WDT cord-022526-j9kg00qf 1061 12 stimulates stimulate VBZ cord-022526-j9kg00qf 1061 13 rather rather RB cord-022526-j9kg00qf 1061 14 than than IN cord-022526-j9kg00qf 1061 15 destroys destroy VBZ cord-022526-j9kg00qf 1061 16 sensory sensory JJ cord-022526-j9kg00qf 1061 17 nerves nerve NNS cord-022526-j9kg00qf 1061 18 , , , cord-022526-j9kg00qf 1061 19 protects protect VBZ cord-022526-j9kg00qf 1061 20 gastric gastric JJ cord-022526-j9kg00qf 1061 21 mucosa mucosa NN cord-022526-j9kg00qf 1061 22 against against IN cord-022526-j9kg00qf 1061 23 injurious injurious JJ cord-022526-j9kg00qf 1061 24 agents agent NNS cord-022526-j9kg00qf 1061 25 . . . cord-022526-j9kg00qf 1062 1 37,38 37,38 CD cord-022526-j9kg00qf 1062 2 Sensory sensory JJ cord-022526-j9kg00qf 1062 3 nerves nerve NNS cord-022526-j9kg00qf 1062 4 contain contain VBP cord-022526-j9kg00qf 1062 5 neuropeptides neuropeptide NNS cord-022526-j9kg00qf 1062 6 such such JJ cord-022526-j9kg00qf 1062 7 as as IN cord-022526-j9kg00qf 1062 8 calcitonin calcitonin NN cord-022526-j9kg00qf 1062 9 - - HYPH cord-022526-j9kg00qf 1062 10 gene gene NN cord-022526-j9kg00qf 1062 11 - - HYPH cord-022526-j9kg00qf 1062 12 related relate VBN cord-022526-j9kg00qf 1062 13 peptide peptide NN cord-022526-j9kg00qf 1062 14 ( ( -LRB- cord-022526-j9kg00qf 1062 15 CGRP CGRP NNP cord-022526-j9kg00qf 1062 16 ) ) -RRB- cord-022526-j9kg00qf 1062 17 and and CC cord-022526-j9kg00qf 1062 18 substance substance NN cord-022526-j9kg00qf 1062 19 P p NN cord-022526-j9kg00qf 1062 20 , , , cord-022526-j9kg00qf 1062 21 which which WDT cord-022526-j9kg00qf 1062 22 may may MD cord-022526-j9kg00qf 1062 23 play play VB cord-022526-j9kg00qf 1062 24 a a DT cord-022526-j9kg00qf 1062 25 protective protective JJ cord-022526-j9kg00qf 1062 26 role role NN cord-022526-j9kg00qf 1062 27 via via IN cord-022526-j9kg00qf 1062 28 vascular vascular JJ cord-022526-j9kg00qf 1062 29 mechanisms mechanism NNS cord-022526-j9kg00qf 1062 30 . . . cord-022526-j9kg00qf 1063 1 For for IN cord-022526-j9kg00qf 1063 2 instance instance NN cord-022526-j9kg00qf 1063 3 , , , cord-022526-j9kg00qf 1063 4 CGRP CGRP NNP cord-022526-j9kg00qf 1063 5 stimulates stimulate VBZ cord-022526-j9kg00qf 1063 6 increased increase VBD cord-022526-j9kg00qf 1063 7 gastric gastric JJ cord-022526-j9kg00qf 1063 8 blood blood NN cord-022526-j9kg00qf 1063 9 flow flow NN cord-022526-j9kg00qf 1063 10 , , , cord-022526-j9kg00qf 1063 11 which which WDT cord-022526-j9kg00qf 1063 12 is be VBZ cord-022526-j9kg00qf 1063 13 theorized theorize VBN cord-022526-j9kg00qf 1063 14 to to TO cord-022526-j9kg00qf 1063 15 reduce reduce VB cord-022526-j9kg00qf 1063 16 injury injury NN cord-022526-j9kg00qf 1063 17 in in IN cord-022526-j9kg00qf 1063 18 much much RB cord-022526-j9kg00qf 1063 19 the the DT cord-022526-j9kg00qf 1063 20 same same JJ cord-022526-j9kg00qf 1063 21 way way NN cord-022526-j9kg00qf 1063 22 as as IN cord-022526-j9kg00qf 1063 23 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1063 24 do do VBP cord-022526-j9kg00qf 1063 25 . . . cord-022526-j9kg00qf 1064 1 In in IN cord-022526-j9kg00qf 1064 2 fact fact NN cord-022526-j9kg00qf 1064 3 , , , cord-022526-j9kg00qf 1064 4 recent recent JJ cord-022526-j9kg00qf 1064 5 studies study NNS cord-022526-j9kg00qf 1064 6 suggest suggest VBP cord-022526-j9kg00qf 1064 7 that that IN cord-022526-j9kg00qf 1064 8 the the DT cord-022526-j9kg00qf 1064 9 roles role NNS cord-022526-j9kg00qf 1064 10 of of IN cord-022526-j9kg00qf 1064 11 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1064 12 and and CC cord-022526-j9kg00qf 1064 13 CGRP CGRP NNP cord-022526-j9kg00qf 1064 14 in in IN cord-022526-j9kg00qf 1064 15 gastric gastric JJ cord-022526-j9kg00qf 1064 16 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1064 17 are be VBP cord-022526-j9kg00qf 1064 18 intertwined intertwine VBN cord-022526-j9kg00qf 1064 19 intimately intimately RB cord-022526-j9kg00qf 1064 20 . . . cord-022526-j9kg00qf 1065 1 In in IN cord-022526-j9kg00qf 1065 2 particular particular JJ cord-022526-j9kg00qf 1065 3 , , , cord-022526-j9kg00qf 1065 4 PGI PGI NNP cord-022526-j9kg00qf 1065 5 2 2 CD cord-022526-j9kg00qf 1065 6 is be VBZ cord-022526-j9kg00qf 1065 7 believed believe VBN cord-022526-j9kg00qf 1065 8 to to TO cord-022526-j9kg00qf 1065 9 sensitize sensitize VB cord-022526-j9kg00qf 1065 10 sensory sensory JJ cord-022526-j9kg00qf 1065 11 nerves nerve NNS cord-022526-j9kg00qf 1065 12 following follow VBG cord-022526-j9kg00qf 1065 13 treatment treatment NN cord-022526-j9kg00qf 1065 14 with with IN cord-022526-j9kg00qf 1065 15 a a DT cord-022526-j9kg00qf 1065 16 mild mild JJ cord-022526-j9kg00qf 1065 17 irritant irritant NN cord-022526-j9kg00qf 1065 18 , , , cord-022526-j9kg00qf 1065 19 with with IN cord-022526-j9kg00qf 1065 20 resultant resultant JJ cord-022526-j9kg00qf 1065 21 increases increase NNS cord-022526-j9kg00qf 1065 22 in in IN cord-022526-j9kg00qf 1065 23 CGRP cgrp NN cord-022526-j9kg00qf 1065 24 release release NN cord-022526-j9kg00qf 1065 25 and and CC cord-022526-j9kg00qf 1065 26 mucosal mucosal JJ cord-022526-j9kg00qf 1065 27 flow flow NN cord-022526-j9kg00qf 1065 28 . . . cord-022526-j9kg00qf 1066 1 Similar similar JJ cord-022526-j9kg00qf 1066 2 studies study NNS cord-022526-j9kg00qf 1066 3 have have VBP cord-022526-j9kg00qf 1066 4 shown show VBN cord-022526-j9kg00qf 1066 5 that that IN cord-022526-j9kg00qf 1066 6 antagonists antagonist NNS cord-022526-j9kg00qf 1066 7 of of IN cord-022526-j9kg00qf 1066 8 CGRP CGRP NNP cord-022526-j9kg00qf 1066 9 inhibit inhibit VB cord-022526-j9kg00qf 1066 10 the the DT cord-022526-j9kg00qf 1066 11 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1066 12 action action NN cord-022526-j9kg00qf 1066 13 of of IN cord-022526-j9kg00qf 1066 14 PGE PGE NNP cord-022526-j9kg00qf 1066 15 2 2 CD cord-022526-j9kg00qf 1066 16 . . . cord-022526-j9kg00qf 1067 1 39 39 CD cord-022526-j9kg00qf 1068 1 Another another DT cord-022526-j9kg00qf 1068 2 neural neural JJ cord-022526-j9kg00qf 1068 3 mediator mediator NN cord-022526-j9kg00qf 1068 4 , , , cord-022526-j9kg00qf 1068 5 nitric nitric JJ cord-022526-j9kg00qf 1068 6 oxide oxide NN cord-022526-j9kg00qf 1068 7 , , , cord-022526-j9kg00qf 1068 8 also also RB cord-022526-j9kg00qf 1068 9 has have VBZ cord-022526-j9kg00qf 1068 10 been be VBN cord-022526-j9kg00qf 1068 11 implicated implicate VBN cord-022526-j9kg00qf 1068 12 in in IN cord-022526-j9kg00qf 1068 13 adaptive adaptive JJ cord-022526-j9kg00qf 1068 14 cytoprotection cytoprotection NN cord-022526-j9kg00qf 1068 15 . . . cord-022526-j9kg00qf 1069 1 Interestingly interestingly RB cord-022526-j9kg00qf 1069 2 , , , cord-022526-j9kg00qf 1069 3 nitric nitric JJ cord-022526-j9kg00qf 1069 4 oxide oxide NN cord-022526-j9kg00qf 1069 5 has have VBZ cord-022526-j9kg00qf 1069 6 a a DT cord-022526-j9kg00qf 1069 7 number number NN cord-022526-j9kg00qf 1069 8 of of IN cord-022526-j9kg00qf 1069 9 actions action NNS cord-022526-j9kg00qf 1069 10 that that WDT cord-022526-j9kg00qf 1069 11 are be VBP cord-022526-j9kg00qf 1069 12 similar similar JJ cord-022526-j9kg00qf 1069 13 to to IN cord-022526-j9kg00qf 1069 14 those those DT cord-022526-j9kg00qf 1069 15 of of IN cord-022526-j9kg00qf 1069 16 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1069 17 , , , cord-022526-j9kg00qf 1069 18 including include VBG cord-022526-j9kg00qf 1069 19 maintenance maintenance NN cord-022526-j9kg00qf 1069 20 of of IN cord-022526-j9kg00qf 1069 21 mucosal mucosal JJ cord-022526-j9kg00qf 1069 22 blood blood NN cord-022526-j9kg00qf 1069 23 flow flow NN cord-022526-j9kg00qf 1069 24 . . . cord-022526-j9kg00qf 1070 1 40 40 CD cord-022526-j9kg00qf 1070 2 Regulation regulation NN cord-022526-j9kg00qf 1070 3 of of IN cord-022526-j9kg00qf 1070 4 barrier barrier NN cord-022526-j9kg00qf 1070 5 function function NN cord-022526-j9kg00qf 1070 6 in in IN cord-022526-j9kg00qf 1070 7 the the DT cord-022526-j9kg00qf 1070 8 intestine intestine NN cord-022526-j9kg00qf 1070 9 is be VBZ cord-022526-j9kg00qf 1070 10 not not RB cord-022526-j9kg00qf 1070 11 as as RB cord-022526-j9kg00qf 1070 12 well well RB cord-022526-j9kg00qf 1070 13 characterized characterize VBN cord-022526-j9kg00qf 1070 14 as as IN cord-022526-j9kg00qf 1070 15 that that DT cord-022526-j9kg00qf 1070 16 of of IN cord-022526-j9kg00qf 1070 17 the the DT cord-022526-j9kg00qf 1070 18 stomach stomach NN cord-022526-j9kg00qf 1070 19 , , , cord-022526-j9kg00qf 1070 20 although although IN cord-022526-j9kg00qf 1070 21 mechanisms mechanism NNS cord-022526-j9kg00qf 1070 22 of of IN cord-022526-j9kg00qf 1070 23 barrier barrier NN cord-022526-j9kg00qf 1070 24 function function NN cord-022526-j9kg00qf 1070 25 , , , cord-022526-j9kg00qf 1070 26 including include VBG cord-022526-j9kg00qf 1070 27 secretion secretion NN cord-022526-j9kg00qf 1070 28 of of IN cord-022526-j9kg00qf 1070 29 mucus mucus NN cord-022526-j9kg00qf 1070 30 and and CC cord-022526-j9kg00qf 1070 31 regulation regulation NN cord-022526-j9kg00qf 1070 32 of of IN cord-022526-j9kg00qf 1070 33 mucosal mucosal JJ cord-022526-j9kg00qf 1070 34 blood blood NN cord-022526-j9kg00qf 1070 35 flow flow NN cord-022526-j9kg00qf 1070 36 , , , cord-022526-j9kg00qf 1070 37 are be VBP cord-022526-j9kg00qf 1070 38 presumed presume VBN cord-022526-j9kg00qf 1070 39 to to TO cord-022526-j9kg00qf 1070 40 be be VB cord-022526-j9kg00qf 1070 41 similar similar JJ cord-022526-j9kg00qf 1070 42 . . . cord-022526-j9kg00qf 1071 1 The the DT cord-022526-j9kg00qf 1071 2 proximal proximal JJ cord-022526-j9kg00qf 1071 3 duodenum duodenum NN cord-022526-j9kg00qf 1071 4 also also RB cord-022526-j9kg00qf 1071 5 has have VBZ cord-022526-j9kg00qf 1071 6 to to TO cord-022526-j9kg00qf 1071 7 protect protect VB cord-022526-j9kg00qf 1071 8 itself -PRON- PRP cord-022526-j9kg00qf 1071 9 from from IN cord-022526-j9kg00qf 1071 10 acid acid JJ cord-022526-j9kg00qf 1071 11 damage damage NN cord-022526-j9kg00qf 1071 12 as as IN cord-022526-j9kg00qf 1071 13 it -PRON- PRP cord-022526-j9kg00qf 1071 14 receives receive VBZ cord-022526-j9kg00qf 1071 15 gastric gastric JJ cord-022526-j9kg00qf 1071 16 contents content NNS cord-022526-j9kg00qf 1071 17 , , , cord-022526-j9kg00qf 1071 18 and and CC cord-022526-j9kg00qf 1071 19 this this DT cord-022526-j9kg00qf 1071 20 involves involve VBZ cord-022526-j9kg00qf 1071 21 secretion secretion NN cord-022526-j9kg00qf 1071 22 of of IN cord-022526-j9kg00qf 1071 23 mucus mucus NN cord-022526-j9kg00qf 1071 24 and and CC cord-022526-j9kg00qf 1071 25 bicarbonate bicarbonate NN cord-022526-j9kg00qf 1071 26 in in IN cord-022526-j9kg00qf 1071 27 much much RB cord-022526-j9kg00qf 1071 28 the the DT cord-022526-j9kg00qf 1071 29 same same JJ cord-022526-j9kg00qf 1071 30 way way NN cord-022526-j9kg00qf 1071 31 as as IN cord-022526-j9kg00qf 1071 32 the the DT cord-022526-j9kg00qf 1071 33 stomach stomach NN cord-022526-j9kg00qf 1071 34 . . . cord-022526-j9kg00qf 1072 1 One one CD cord-022526-j9kg00qf 1072 2 other other JJ cord-022526-j9kg00qf 1072 3 mechanism mechanism NN cord-022526-j9kg00qf 1072 4 that that WDT cord-022526-j9kg00qf 1072 5 helps help VBZ cord-022526-j9kg00qf 1072 6 the the DT cord-022526-j9kg00qf 1072 7 stomach stomach NN cord-022526-j9kg00qf 1072 8 and and CC cord-022526-j9kg00qf 1072 9 the the DT cord-022526-j9kg00qf 1072 10 intestine intestine NN cord-022526-j9kg00qf 1072 11 to to TO cord-022526-j9kg00qf 1072 12 maintain maintain VB cord-022526-j9kg00qf 1072 13 mucosal mucosal JJ cord-022526-j9kg00qf 1072 14 barrier barrier NN cord-022526-j9kg00qf 1072 15 function function NN cord-022526-j9kg00qf 1072 16 is be VBZ cord-022526-j9kg00qf 1072 17 the the DT cord-022526-j9kg00qf 1072 18 speed speed NN cord-022526-j9kg00qf 1072 19 with with IN cord-022526-j9kg00qf 1072 20 which which WDT cord-022526-j9kg00qf 1072 21 the the DT cord-022526-j9kg00qf 1072 22 mucosa mucosa JJ cord-022526-j9kg00qf 1072 23 repairs repair NNS cord-022526-j9kg00qf 1072 24 . . . cord-022526-j9kg00qf 1073 1 Thus thus RB cord-022526-j9kg00qf 1073 2 for for IN cord-022526-j9kg00qf 1073 3 a a DT cord-022526-j9kg00qf 1073 4 defect defect NN cord-022526-j9kg00qf 1073 5 to to TO cord-022526-j9kg00qf 1073 6 develop develop VB cord-022526-j9kg00qf 1073 7 in in IN cord-022526-j9kg00qf 1073 8 the the DT cord-022526-j9kg00qf 1073 9 mucosal mucosal JJ cord-022526-j9kg00qf 1073 10 barrier barrier NN cord-022526-j9kg00qf 1073 11 , , , cord-022526-j9kg00qf 1073 12 injurious injurious JJ cord-022526-j9kg00qf 1073 13 factors factor NNS cord-022526-j9kg00qf 1073 14 have have VBP cord-022526-j9kg00qf 1073 15 to to TO cord-022526-j9kg00qf 1073 16 outpace outpace VB cord-022526-j9kg00qf 1073 17 mucosal mucosal JJ cord-022526-j9kg00qf 1073 18 recovery recovery NN cord-022526-j9kg00qf 1073 19 . . . cord-022526-j9kg00qf 1074 1 Such such JJ cord-022526-j9kg00qf 1074 2 recovery recovery NN cord-022526-j9kg00qf 1074 3 initially initially RB cord-022526-j9kg00qf 1074 4 involves involve VBZ cord-022526-j9kg00qf 1074 5 epithelial epithelial JJ cord-022526-j9kg00qf 1074 6 migration migration NN cord-022526-j9kg00qf 1074 7 across across IN cord-022526-j9kg00qf 1074 8 denuded denude VBN cord-022526-j9kg00qf 1074 9 regions region NNS cord-022526-j9kg00qf 1074 10 of of IN cord-022526-j9kg00qf 1074 11 basement basement NN cord-022526-j9kg00qf 1074 12 membrane membrane NN cord-022526-j9kg00qf 1074 13 ( ( -LRB- cord-022526-j9kg00qf 1074 14 restitution restitution NN cord-022526-j9kg00qf 1074 15 ) ) -RRB- cord-022526-j9kg00qf 1074 16 , , , cord-022526-j9kg00qf 1074 17 26 26 CD cord-022526-j9kg00qf 1074 18 a a DT cord-022526-j9kg00qf 1074 19 process process NN cord-022526-j9kg00qf 1074 20 so so RB cord-022526-j9kg00qf 1074 21 rapid rapid JJ cord-022526-j9kg00qf 1074 22 that that IN cord-022526-j9kg00qf 1074 23 epithelial epithelial JJ cord-022526-j9kg00qf 1074 24 defects defect NNS cord-022526-j9kg00qf 1074 25 may may MD cord-022526-j9kg00qf 1074 26 be be VB cord-022526-j9kg00qf 1074 27 resurfaced resurface VBN cord-022526-j9kg00qf 1074 28 within within IN cord-022526-j9kg00qf 1074 29 minutes minute NNS cord-022526-j9kg00qf 1074 30 . . . cord-022526-j9kg00qf 1075 1 For for IN cord-022526-j9kg00qf 1075 2 example example NN cord-022526-j9kg00qf 1075 3 , , , cord-022526-j9kg00qf 1075 4 in in IN cord-022526-j9kg00qf 1075 5 bile bile NN cord-022526-j9kg00qf 1075 6 salt salt NN cord-022526-j9kg00qf 1075 7 - - HYPH cord-022526-j9kg00qf 1075 8 injured injure VBN cord-022526-j9kg00qf 1075 9 colon colon NN cord-022526-j9kg00qf 1075 10 , , , cord-022526-j9kg00qf 1075 11 denuded denude VBN cord-022526-j9kg00qf 1075 12 surface surface NN cord-022526-j9kg00qf 1075 13 mucosa mucosa NN cord-022526-j9kg00qf 1075 14 was be VBD cord-022526-j9kg00qf 1075 15 covered cover VBN cord-022526-j9kg00qf 1075 16 completely completely RB cord-022526-j9kg00qf 1075 17 by by IN cord-022526-j9kg00qf 1075 18 restitution restitution NN cord-022526-j9kg00qf 1075 19 . . . cord-022526-j9kg00qf 1076 1 41 41 CD cord-022526-j9kg00qf 1077 1 In in IN cord-022526-j9kg00qf 1077 2 the the DT cord-022526-j9kg00qf 1077 3 small small JJ cord-022526-j9kg00qf 1077 4 intestine intestine NN cord-022526-j9kg00qf 1077 5 , , , cord-022526-j9kg00qf 1077 6 villi villi NNP cord-022526-j9kg00qf 1077 7 greatly greatly RB cord-022526-j9kg00qf 1077 8 amplify amplify VBP cord-022526-j9kg00qf 1077 9 the the DT cord-022526-j9kg00qf 1077 10 surface surface NN cord-022526-j9kg00qf 1077 11 area area NN cord-022526-j9kg00qf 1077 12 of of IN cord-022526-j9kg00qf 1077 13 the the DT cord-022526-j9kg00qf 1077 14 mucosal mucosal JJ cord-022526-j9kg00qf 1077 15 luminal luminal JJ cord-022526-j9kg00qf 1077 16 surface surface NN cord-022526-j9kg00qf 1077 17 , , , cord-022526-j9kg00qf 1077 18 which which WDT cord-022526-j9kg00qf 1077 19 in in IN cord-022526-j9kg00qf 1077 20 turn turn NN cord-022526-j9kg00qf 1077 21 takes take VBZ cord-022526-j9kg00qf 1077 22 far far RB cord-022526-j9kg00qf 1077 23 longer long RBR cord-022526-j9kg00qf 1077 24 to to TO cord-022526-j9kg00qf 1077 25 resurface resurface VB cord-022526-j9kg00qf 1077 26 with with IN cord-022526-j9kg00qf 1077 27 restituting restitute VBG cord-022526-j9kg00qf 1077 28 epithelium epithelium NN cord-022526-j9kg00qf 1077 29 once once IN cord-022526-j9kg00qf 1077 30 it -PRON- PRP cord-022526-j9kg00qf 1077 31 has have VBZ cord-022526-j9kg00qf 1077 32 become become VBN cord-022526-j9kg00qf 1077 33 denuded denude VBN cord-022526-j9kg00qf 1077 34 . . . cord-022526-j9kg00qf 1078 1 42 42 CD cord-022526-j9kg00qf 1079 1 However however RB cord-022526-j9kg00qf 1079 2 , , , cord-022526-j9kg00qf 1079 3 intestinal intestinal JJ cord-022526-j9kg00qf 1079 4 villi villus NNS cord-022526-j9kg00qf 1079 5 are be VBP cord-022526-j9kg00qf 1079 6 able able JJ cord-022526-j9kg00qf 1079 7 to to TO cord-022526-j9kg00qf 1079 8 reduce reduce VB cord-022526-j9kg00qf 1079 9 the the DT cord-022526-j9kg00qf 1079 10 denuded denude VBN cord-022526-j9kg00qf 1079 11 surface surface NN cord-022526-j9kg00qf 1079 12 area area NN cord-022526-j9kg00qf 1079 13 considerably considerably RB cord-022526-j9kg00qf 1079 14 by by IN cord-022526-j9kg00qf 1079 15 extensively extensively RB cord-022526-j9kg00qf 1079 16 contracting contract VBG cord-022526-j9kg00qf 1079 17 . . . cord-022526-j9kg00qf 1080 1 43 43 CD cord-022526-j9kg00qf 1081 1 These these DT cord-022526-j9kg00qf 1081 2 mechanisms mechanism NNS cord-022526-j9kg00qf 1081 3 are be VBP cord-022526-j9kg00qf 1081 4 described describe VBN cord-022526-j9kg00qf 1081 5 in in IN cord-022526-j9kg00qf 1081 6 detail detail NN cord-022526-j9kg00qf 1081 7 under under IN cord-022526-j9kg00qf 1081 8 Mechanisms Mechanisms NNPS cord-022526-j9kg00qf 1081 9 of of IN cord-022526-j9kg00qf 1081 10 Gastrointestinal Gastrointestinal NNP cord-022526-j9kg00qf 1081 11 Mucosal Mucosal NNP cord-022526-j9kg00qf 1081 12 Repair Repair NNP cord-022526-j9kg00qf 1081 13 . . . cord-022526-j9kg00qf 1082 1 Although although IN cord-022526-j9kg00qf 1082 2 the the DT cord-022526-j9kg00qf 1082 3 stratified stratified JJ cord-022526-j9kg00qf 1082 4 squamous squamous JJ cord-022526-j9kg00qf 1082 5 epithelium epithelium NN cord-022526-j9kg00qf 1082 6 is be VBZ cord-022526-j9kg00qf 1082 7 relatively relatively RB cord-022526-j9kg00qf 1082 8 impermeable impermeable JJ cord-022526-j9kg00qf 1082 9 to to IN cord-022526-j9kg00qf 1082 10 HCl HCl NNP cord-022526-j9kg00qf 1082 11 , , , cord-022526-j9kg00qf 1082 12 a a DT cord-022526-j9kg00qf 1082 13 number number NN cord-022526-j9kg00qf 1082 14 of of IN cord-022526-j9kg00qf 1082 15 factors factor NNS cord-022526-j9kg00qf 1082 16 can can MD cord-022526-j9kg00qf 1082 17 enhance enhance VB cord-022526-j9kg00qf 1082 18 the the DT cord-022526-j9kg00qf 1082 19 damaging damaging JJ cord-022526-j9kg00qf 1082 20 effects effect NNS cord-022526-j9kg00qf 1082 21 of of IN cord-022526-j9kg00qf 1082 22 HCl hcl NN cord-022526-j9kg00qf 1082 23 in in IN cord-022526-j9kg00qf 1082 24 this this DT cord-022526-j9kg00qf 1082 25 epithelium epithelium NN cord-022526-j9kg00qf 1082 26 . . . cord-022526-j9kg00qf 1083 1 In in IN cord-022526-j9kg00qf 1083 2 particular particular JJ cord-022526-j9kg00qf 1083 3 , , , cord-022526-j9kg00qf 1083 4 bile bile NN cord-022526-j9kg00qf 1083 5 salts salt NNS cord-022526-j9kg00qf 1083 6 and and CC cord-022526-j9kg00qf 1083 7 short short JJ cord-022526-j9kg00qf 1083 8 - - HYPH cord-022526-j9kg00qf 1083 9 chain chain NN cord-022526-j9kg00qf 1083 10 fatty fatty JJ cord-022526-j9kg00qf 1083 11 acids acid NNS cord-022526-j9kg00qf 1083 12 are be VBP cord-022526-j9kg00qf 1083 13 capable capable JJ cord-022526-j9kg00qf 1083 14 of of IN cord-022526-j9kg00qf 1083 15 breaking break VBG cord-022526-j9kg00qf 1083 16 down down RP cord-022526-j9kg00qf 1083 17 the the DT cord-022526-j9kg00qf 1083 18 squamous squamous JJ cord-022526-j9kg00qf 1083 19 epithelial epithelial JJ cord-022526-j9kg00qf 1083 20 barrier barrier NN cord-022526-j9kg00qf 1083 21 at at IN cord-022526-j9kg00qf 1083 22 an an DT cord-022526-j9kg00qf 1083 23 acid acid NN cord-022526-j9kg00qf 1083 24 pH ph NN cord-022526-j9kg00qf 1083 25 , , , cord-022526-j9kg00qf 1083 26 thereby thereby RB cord-022526-j9kg00qf 1083 27 exposing expose VBG cord-022526-j9kg00qf 1083 28 deep deep JJ cord-022526-j9kg00qf 1083 29 layers layer NNS cord-022526-j9kg00qf 1083 30 to to IN cord-022526-j9kg00qf 1083 31 HCl HCl NNP cord-022526-j9kg00qf 1083 32 , , , cord-022526-j9kg00qf 1083 33 with with IN cord-022526-j9kg00qf 1083 34 subsequent subsequent JJ cord-022526-j9kg00qf 1083 35 development development NN cord-022526-j9kg00qf 1083 36 of of IN cord-022526-j9kg00qf 1083 37 ulceration ulceration NN cord-022526-j9kg00qf 1083 38 . . . cord-022526-j9kg00qf 1084 1 18 18 CD cord-022526-j9kg00qf 1084 2 , , , cord-022526-j9kg00qf 1084 3 44 44 CD cord-022526-j9kg00qf 1084 4 High high JJ cord-022526-j9kg00qf 1084 5 concentrations concentration NNS cord-022526-j9kg00qf 1084 6 of of IN cord-022526-j9kg00qf 1084 7 short short JJ cord-022526-j9kg00qf 1084 8 - - HYPH cord-022526-j9kg00qf 1084 9 chain chain NN cord-022526-j9kg00qf 1084 10 fatty fatty JJ cord-022526-j9kg00qf 1084 11 acids acid NNS cord-022526-j9kg00qf 1084 12 normally normally RB cord-022526-j9kg00qf 1084 13 exist exist VBP cord-022526-j9kg00qf 1084 14 within within IN cord-022526-j9kg00qf 1084 15 the the DT cord-022526-j9kg00qf 1084 16 equine equine JJ cord-022526-j9kg00qf 1084 17 stomach stomach NN cord-022526-j9kg00qf 1084 18 because because IN cord-022526-j9kg00qf 1084 19 of of IN cord-022526-j9kg00qf 1084 20 microbial microbial JJ cord-022526-j9kg00qf 1084 21 fermentation fermentation NN cord-022526-j9kg00qf 1084 22 . . . cord-022526-j9kg00qf 1085 1 17 17 CD cord-022526-j9kg00qf 1086 1 These these DT cord-022526-j9kg00qf 1086 2 weak weak JJ cord-022526-j9kg00qf 1086 3 acids acid NNS cord-022526-j9kg00qf 1086 4 penetrate penetrate VBP cord-022526-j9kg00qf 1086 5 squamous squamous JJ cord-022526-j9kg00qf 1086 6 mucosa mucosa NN cord-022526-j9kg00qf 1086 7 and and CC cord-022526-j9kg00qf 1086 8 appear appear VBP cord-022526-j9kg00qf 1086 9 to to TO cord-022526-j9kg00qf 1086 10 damage damage VB cord-022526-j9kg00qf 1086 11 Na Na NNP cord-022526-j9kg00qf 1086 12 + + CC cord-022526-j9kg00qf 1086 13 transport transport NN cord-022526-j9kg00qf 1086 14 activity activity NN cord-022526-j9kg00qf 1086 15 principally principally RB cord-022526-j9kg00qf 1086 16 located locate VBN cord-022526-j9kg00qf 1086 17 in in IN cord-022526-j9kg00qf 1086 18 the the DT cord-022526-j9kg00qf 1086 19 stratum stratum NN cord-022526-j9kg00qf 1086 20 germinativum germinativum NN cord-022526-j9kg00qf 1086 21 . . . cord-022526-j9kg00qf 1087 1 Bile bile NN cord-022526-j9kg00qf 1087 2 salts salt NNS cord-022526-j9kg00qf 1087 3 also also RB cord-022526-j9kg00qf 1087 4 may may MD cord-022526-j9kg00qf 1087 5 be be VB cord-022526-j9kg00qf 1087 6 present present JJ cord-022526-j9kg00qf 1087 7 in in IN cord-022526-j9kg00qf 1087 8 the the DT cord-022526-j9kg00qf 1087 9 proximal proximal JJ cord-022526-j9kg00qf 1087 10 stomach stomach NN cord-022526-j9kg00qf 1087 11 because because IN cord-022526-j9kg00qf 1087 12 of of IN cord-022526-j9kg00qf 1087 13 reflux reflux NN cord-022526-j9kg00qf 1087 14 from from IN cord-022526-j9kg00qf 1087 15 the the DT cord-022526-j9kg00qf 1087 16 duodenum duodenum NN cord-022526-j9kg00qf 1087 17 . . . cord-022526-j9kg00qf 1088 1 Although although IN cord-022526-j9kg00qf 1088 2 such such JJ cord-022526-j9kg00qf 1088 3 reflux reflux NN cord-022526-j9kg00qf 1088 4 has have VBZ cord-022526-j9kg00qf 1088 5 a a DT cord-022526-j9kg00qf 1088 6 high high JJ cord-022526-j9kg00qf 1088 7 pH ph NN cord-022526-j9kg00qf 1088 8 , , , cord-022526-j9kg00qf 1088 9 bile bile NN cord-022526-j9kg00qf 1088 10 salts salt NNS cord-022526-j9kg00qf 1088 11 appear appear VBP cord-022526-j9kg00qf 1088 12 to to TO cord-022526-j9kg00qf 1088 13 adhere adhere VB cord-022526-j9kg00qf 1088 14 to to IN cord-022526-j9kg00qf 1088 15 stratified stratified JJ cord-022526-j9kg00qf 1088 16 squamous squamous JJ cord-022526-j9kg00qf 1088 17 epithelium epithelium NN cord-022526-j9kg00qf 1088 18 , , , cord-022526-j9kg00qf 1088 19 becoming become VBG cord-022526-j9kg00qf 1088 20 lipid lipid NN cord-022526-j9kg00qf 1088 21 soluble soluble JJ cord-022526-j9kg00qf 1088 22 and and CC cord-022526-j9kg00qf 1088 23 triggering trigger VBG cord-022526-j9kg00qf 1088 24 damage damage NN cord-022526-j9kg00qf 1088 25 once once IN cord-022526-j9kg00qf 1088 26 the the DT cord-022526-j9kg00qf 1088 27 pH pH NNP cord-022526-j9kg00qf 1088 28 falls fall VBZ cord-022526-j9kg00qf 1088 29 below below IN cord-022526-j9kg00qf 1088 30 4 4 CD cord-022526-j9kg00qf 1088 31 . . . cord-022526-j9kg00qf 1089 1 45 45 CD cord-022526-j9kg00qf 1089 2 Diet diet NN cord-022526-j9kg00qf 1089 3 and and CC cord-022526-j9kg00qf 1089 4 management management NN cord-022526-j9kg00qf 1089 5 ( ( -LRB- cord-022526-j9kg00qf 1089 6 e.g. e.g. RB cord-022526-j9kg00qf 1089 7 , , , cord-022526-j9kg00qf 1089 8 periods period NNS cord-022526-j9kg00qf 1089 9 of of IN cord-022526-j9kg00qf 1089 10 fasting fast VBG cord-022526-j9kg00qf 1089 11 ) ) -RRB- cord-022526-j9kg00qf 1089 12 also also RB cord-022526-j9kg00qf 1089 13 play play VB cord-022526-j9kg00qf 1089 14 crucial crucial JJ cord-022526-j9kg00qf 1089 15 roles role NNS cord-022526-j9kg00qf 1089 16 in in IN cord-022526-j9kg00qf 1089 17 the the DT cord-022526-j9kg00qf 1089 18 development development NN cord-022526-j9kg00qf 1089 19 of of IN cord-022526-j9kg00qf 1089 20 conditions condition NNS cord-022526-j9kg00qf 1089 21 conducive conducive JJ cord-022526-j9kg00qf 1089 22 to to IN cord-022526-j9kg00qf 1089 23 gastric gastric JJ cord-022526-j9kg00qf 1089 24 ulceration ulceration NN cord-022526-j9kg00qf 1089 25 . . . cord-022526-j9kg00qf 1090 1 Typically typically RB cord-022526-j9kg00qf 1090 2 , , , cord-022526-j9kg00qf 1090 3 a a DT cord-022526-j9kg00qf 1090 4 pH ph NN cord-022526-j9kg00qf 1090 5 gradation gradation NN cord-022526-j9kg00qf 1090 6 in in IN cord-022526-j9kg00qf 1090 7 horses horse NNS cord-022526-j9kg00qf 1090 8 exists exist VBZ cord-022526-j9kg00qf 1090 9 from from IN cord-022526-j9kg00qf 1090 10 proximal proximal JJ cord-022526-j9kg00qf 1090 11 to to IN cord-022526-j9kg00qf 1090 12 distal distal JJ cord-022526-j9kg00qf 1090 13 compartments compartment NNS cord-022526-j9kg00qf 1090 14 of of IN cord-022526-j9kg00qf 1090 15 the the DT cord-022526-j9kg00qf 1090 16 stomach stomach NN cord-022526-j9kg00qf 1090 17 , , , cord-022526-j9kg00qf 1090 18 with with IN cord-022526-j9kg00qf 1090 19 the the DT cord-022526-j9kg00qf 1090 20 lowest low JJS cord-022526-j9kg00qf 1090 21 pH pH NNP cord-022526-j9kg00qf 1090 22 values value NNS cord-022526-j9kg00qf 1090 23 in in IN cord-022526-j9kg00qf 1090 24 the the DT cord-022526-j9kg00qf 1090 25 distal distal JJ cord-022526-j9kg00qf 1090 26 stomach stomach NN cord-022526-j9kg00qf 1090 27 . . . cord-022526-j9kg00qf 1091 1 46 46 CD cord-022526-j9kg00qf 1092 1 However however RB cord-022526-j9kg00qf 1092 2 , , , cord-022526-j9kg00qf 1092 3 fasting fast VBG cord-022526-j9kg00qf 1092 4 disrupts disrupt VBZ cord-022526-j9kg00qf 1092 5 this this DT cord-022526-j9kg00qf 1092 6 stratification stratification NN cord-022526-j9kg00qf 1092 7 such such JJ cord-022526-j9kg00qf 1092 8 that that IN cord-022526-j9kg00qf 1092 9 low low JJ cord-022526-j9kg00qf 1092 10 pH ph NN cord-022526-j9kg00qf 1092 11 values value NNS cord-022526-j9kg00qf 1092 12 may may MD cord-022526-j9kg00qf 1092 13 be be VB cord-022526-j9kg00qf 1092 14 recorded record VBN cord-022526-j9kg00qf 1092 15 in in IN cord-022526-j9kg00qf 1092 16 the the DT cord-022526-j9kg00qf 1092 17 proximal proximal JJ cord-022526-j9kg00qf 1092 18 stomach stomach NN cord-022526-j9kg00qf 1092 19 . . . cord-022526-j9kg00qf 1093 1 47 47 CD cord-022526-j9kg00qf 1094 1 Fasting fasting NN cord-022526-j9kg00qf 1094 2 conditions condition NNS cord-022526-j9kg00qf 1094 3 also also RB cord-022526-j9kg00qf 1094 4 increase increase VBP cord-022526-j9kg00qf 1094 5 the the DT cord-022526-j9kg00qf 1094 6 concentration concentration NN cord-022526-j9kg00qf 1094 7 of of IN cord-022526-j9kg00qf 1094 8 duodenal duodenal JJ cord-022526-j9kg00qf 1094 9 contents content NNS cord-022526-j9kg00qf 1094 10 within within IN cord-022526-j9kg00qf 1094 11 the the DT cord-022526-j9kg00qf 1094 12 proximal proximal JJ cord-022526-j9kg00qf 1094 13 stomach stomach NN cord-022526-j9kg00qf 1094 14 , , , cord-022526-j9kg00qf 1094 15 particularly particularly RB cord-022526-j9kg00qf 1094 16 bile bile NN cord-022526-j9kg00qf 1094 17 . . . cord-022526-j9kg00qf 1095 1 45 45 CD cord-022526-j9kg00qf 1095 2 _SP cord-022526-j9kg00qf 1096 1 Proper proper JJ cord-022526-j9kg00qf 1096 2 gastric gastric JJ cord-022526-j9kg00qf 1096 3 mucosa mucosa NN cord-022526-j9kg00qf 1096 4 is be VBZ cord-022526-j9kg00qf 1096 5 exposed expose VBN cord-022526-j9kg00qf 1096 6 to to IN cord-022526-j9kg00qf 1096 7 injurious injurious JJ cord-022526-j9kg00qf 1096 8 agents agent NNS cord-022526-j9kg00qf 1096 9 , , , cord-022526-j9kg00qf 1096 10 including include VBG cord-022526-j9kg00qf 1096 11 pepsin pepsin NN cord-022526-j9kg00qf 1096 12 , , , cord-022526-j9kg00qf 1096 13 bile bile NN cord-022526-j9kg00qf 1096 14 , , , cord-022526-j9kg00qf 1096 15 and and CC cord-022526-j9kg00qf 1096 16 acid acid NN cord-022526-j9kg00qf 1096 17 . . . cord-022526-j9kg00qf 1097 1 Parietal parietal JJ cord-022526-j9kg00qf 1097 2 cells cell NNS cord-022526-j9kg00qf 1097 3 in in IN cord-022526-j9kg00qf 1097 4 the the DT cord-022526-j9kg00qf 1097 5 horse horse NN cord-022526-j9kg00qf 1097 6 secrete secrete NN cord-022526-j9kg00qf 1097 7 acid acid NN cord-022526-j9kg00qf 1097 8 constantly constantly RB cord-022526-j9kg00qf 1097 9 as as IN cord-022526-j9kg00qf 1097 10 an an DT cord-022526-j9kg00qf 1097 11 adaptation adaptation NN cord-022526-j9kg00qf 1097 12 to to IN cord-022526-j9kg00qf 1097 13 near near JJ cord-022526-j9kg00qf 1097 14 - - HYPH cord-022526-j9kg00qf 1097 15 continuous continuous JJ cord-022526-j9kg00qf 1097 16 intake intake NN cord-022526-j9kg00qf 1097 17 of of IN cord-022526-j9kg00qf 1097 18 roughage roughage NN cord-022526-j9kg00qf 1097 19 , , , cord-022526-j9kg00qf 1097 20 16 16 CD cord-022526-j9kg00qf 1097 21 but but CC cord-022526-j9kg00qf 1097 22 the the DT cord-022526-j9kg00qf 1097 23 enterochromaffin enterochromaffin NN cord-022526-j9kg00qf 1097 24 - - HYPH cord-022526-j9kg00qf 1097 25 like like JJ cord-022526-j9kg00qf 1097 26 cells cell NNS cord-022526-j9kg00qf 1097 27 within within IN cord-022526-j9kg00qf 1097 28 the the DT cord-022526-j9kg00qf 1097 29 proper proper JJ cord-022526-j9kg00qf 1097 30 gastric gastric JJ cord-022526-j9kg00qf 1097 31 mucosa mucosa NN cord-022526-j9kg00qf 1097 32 and and CC cord-022526-j9kg00qf 1098 1 G g NN cord-022526-j9kg00qf 1098 2 and and CC cord-022526-j9kg00qf 1098 3 D d NN cord-022526-j9kg00qf 1098 4 cells cell NNS cord-022526-j9kg00qf 1098 5 within within IN cord-022526-j9kg00qf 1098 6 the the DT cord-022526-j9kg00qf 1098 7 pyloric pyloric JJ cord-022526-j9kg00qf 1098 8 mucosa mucosa NN cord-022526-j9kg00qf 1098 9 tightly tightly RB cord-022526-j9kg00qf 1098 10 regulate regulate VBP cord-022526-j9kg00qf 1098 11 acid acid JJ cord-022526-j9kg00qf 1098 12 secretion secretion NN cord-022526-j9kg00qf 1098 13 . . . cord-022526-j9kg00qf 1099 1 Histamine histamine NN cord-022526-j9kg00qf 1099 2 released release VBN cord-022526-j9kg00qf 1099 3 by by IN cord-022526-j9kg00qf 1099 4 enterochromaffin enterochromaffin NN cord-022526-j9kg00qf 1099 5 - - HYPH cord-022526-j9kg00qf 1099 6 like like JJ cord-022526-j9kg00qf 1099 7 cells cell NNS cord-022526-j9kg00qf 1099 8 amplifies amplify VBZ cord-022526-j9kg00qf 1099 9 acid acid JJ cord-022526-j9kg00qf 1099 10 secretion secretion NN cord-022526-j9kg00qf 1099 11 and and CC cord-022526-j9kg00qf 1099 12 interacts interact VBZ cord-022526-j9kg00qf 1099 13 with with IN cord-022526-j9kg00qf 1099 14 H H NNP cord-022526-j9kg00qf 1099 15 2 2 CD cord-022526-j9kg00qf 1099 16 receptors receptor NNS cord-022526-j9kg00qf 1099 17 on on IN cord-022526-j9kg00qf 1099 18 parietal parietal JJ cord-022526-j9kg00qf 1099 19 cells cell NNS cord-022526-j9kg00qf 1099 20 and and CC cord-022526-j9kg00qf 1099 21 G g NN cord-022526-j9kg00qf 1099 22 cells cell NNS cord-022526-j9kg00qf 1099 23 , , , cord-022526-j9kg00qf 1099 24 which which WDT cord-022526-j9kg00qf 1099 25 release release VBP cord-022526-j9kg00qf 1099 26 the the DT cord-022526-j9kg00qf 1099 27 prosecretory prosecretory NNP cord-022526-j9kg00qf 1099 28 hormone hormone NN cord-022526-j9kg00qf 1099 29 gastrin gastrin NN cord-022526-j9kg00qf 1099 30 . . . cord-022526-j9kg00qf 1100 1 A a DT cord-022526-j9kg00qf 1100 2 combination combination NN cord-022526-j9kg00qf 1100 3 of of IN cord-022526-j9kg00qf 1100 4 histamine histamine NN cord-022526-j9kg00qf 1100 5 and and CC cord-022526-j9kg00qf 1100 6 gastrin gastrin NN cord-022526-j9kg00qf 1100 7 can can MD cord-022526-j9kg00qf 1100 8 have have VB cord-022526-j9kg00qf 1100 9 a a DT cord-022526-j9kg00qf 1100 10 synergistic synergistic JJ cord-022526-j9kg00qf 1100 11 effect effect NN cord-022526-j9kg00qf 1100 12 on on IN cord-022526-j9kg00qf 1100 13 parietal parietal JJ cord-022526-j9kg00qf 1100 14 cell cell NN cord-022526-j9kg00qf 1100 15 gastric gastric JJ cord-022526-j9kg00qf 1100 16 secretion secretion NN cord-022526-j9kg00qf 1100 17 , , , cord-022526-j9kg00qf 1100 18 because because IN cord-022526-j9kg00qf 1100 19 these these DT cord-022526-j9kg00qf 1100 20 mediators mediator NNS cord-022526-j9kg00qf 1100 21 have have VBP cord-022526-j9kg00qf 1100 22 distinct distinct JJ cord-022526-j9kg00qf 1100 23 receptors receptor NNS cord-022526-j9kg00qf 1100 24 and and CC cord-022526-j9kg00qf 1100 25 second second JJ cord-022526-j9kg00qf 1100 26 messengers messenger NNS cord-022526-j9kg00qf 1100 27 . . . cord-022526-j9kg00qf 1101 1 However however RB cord-022526-j9kg00qf 1101 2 , , , cord-022526-j9kg00qf 1101 3 D d NN cord-022526-j9kg00qf 1101 4 cells cell NNS cord-022526-j9kg00qf 1101 5 are be VBP cord-022526-j9kg00qf 1101 6 sensitive sensitive JJ cord-022526-j9kg00qf 1101 7 to to IN cord-022526-j9kg00qf 1101 8 an an DT cord-022526-j9kg00qf 1101 9 acidic acidic JJ cord-022526-j9kg00qf 1101 10 environment environment NN cord-022526-j9kg00qf 1101 11 and and CC cord-022526-j9kg00qf 1101 12 release release VB cord-022526-j9kg00qf 1101 13 somatostatin somatostatin NN cord-022526-j9kg00qf 1101 14 , , , cord-022526-j9kg00qf 1101 15 which which WDT cord-022526-j9kg00qf 1101 16 inhibits inhibit VBZ cord-022526-j9kg00qf 1101 17 acid acid JJ cord-022526-j9kg00qf 1101 18 secretion secretion NN cord-022526-j9kg00qf 1101 19 . . . cord-022526-j9kg00qf 1102 1 48 48 CD cord-022526-j9kg00qf 1103 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 1103 2 , , , cord-022526-j9kg00qf 1103 3 gastric gastric JJ cord-022526-j9kg00qf 1103 4 mucosa mucosa NN cord-022526-j9kg00qf 1103 5 may may MD cord-022526-j9kg00qf 1103 6 be be VB cord-022526-j9kg00qf 1103 7 exposed expose VBN cord-022526-j9kg00qf 1103 8 to to IN cord-022526-j9kg00qf 1103 9 acid acid NN cord-022526-j9kg00qf 1103 10 for for IN cord-022526-j9kg00qf 1103 11 prolonged prolonged JJ cord-022526-j9kg00qf 1103 12 periods period NNS cord-022526-j9kg00qf 1103 13 of of IN cord-022526-j9kg00qf 1103 14 time time NN cord-022526-j9kg00qf 1103 15 , , , cord-022526-j9kg00qf 1103 16 particularly particularly RB cord-022526-j9kg00qf 1103 17 in in IN cord-022526-j9kg00qf 1103 18 horses horse NNS cord-022526-j9kg00qf 1103 19 that that WDT cord-022526-j9kg00qf 1103 20 are be VBP cord-022526-j9kg00qf 1103 21 extensively extensively RB cord-022526-j9kg00qf 1103 22 meal meal NN cord-022526-j9kg00qf 1103 23 fed feed VBN cord-022526-j9kg00qf 1103 24 and and CC cord-022526-j9kg00qf 1103 25 that that WDT cord-022526-j9kg00qf 1103 26 do do VBP cord-022526-j9kg00qf 1103 27 not not RB cord-022526-j9kg00qf 1103 28 have have VB cord-022526-j9kg00qf 1103 29 the the DT cord-022526-j9kg00qf 1103 30 benefit benefit NN cord-022526-j9kg00qf 1103 31 of of IN cord-022526-j9kg00qf 1103 32 roughage roughage NN cord-022526-j9kg00qf 1103 33 , , , cord-022526-j9kg00qf 1103 34 which which WDT cord-022526-j9kg00qf 1103 35 tends tend VBZ cord-022526-j9kg00qf 1103 36 to to TO cord-022526-j9kg00qf 1103 37 buffer buffer VB cord-022526-j9kg00qf 1103 38 stomach stomach NN cord-022526-j9kg00qf 1103 39 contents content NNS cord-022526-j9kg00qf 1103 40 . . . cord-022526-j9kg00qf 1104 1 45 45 CD cord-022526-j9kg00qf 1104 2 , , , cord-022526-j9kg00qf 1104 3 48 48 CD cord-022526-j9kg00qf 1104 4 Aside aside RB cord-022526-j9kg00qf 1104 5 from from IN cord-022526-j9kg00qf 1104 6 peptic peptic JJ cord-022526-j9kg00qf 1104 7 ulceration ulceration NN cord-022526-j9kg00qf 1104 8 induced induce VBN cord-022526-j9kg00qf 1104 9 by by IN cord-022526-j9kg00qf 1104 10 combinations combination NNS cord-022526-j9kg00qf 1104 11 of of IN cord-022526-j9kg00qf 1104 12 acid acid NN cord-022526-j9kg00qf 1104 13 and and CC cord-022526-j9kg00qf 1104 14 pepsin pepsin NN cord-022526-j9kg00qf 1104 15 , , , cord-022526-j9kg00qf 1104 16 research research NN cord-022526-j9kg00qf 1104 17 in in IN cord-022526-j9kg00qf 1104 18 human human JJ cord-022526-j9kg00qf 1104 19 medicine medicine NN cord-022526-j9kg00qf 1104 20 has have VBZ cord-022526-j9kg00qf 1104 21 revealed reveal VBN cord-022526-j9kg00qf 1104 22 the the DT cord-022526-j9kg00qf 1104 23 tremendous tremendous JJ cord-022526-j9kg00qf 1104 24 importance importance NN cord-022526-j9kg00qf 1104 25 of of IN cord-022526-j9kg00qf 1104 26 Helicobacter Helicobacter NNP cord-022526-j9kg00qf 1104 27 pylori pylori NN cord-022526-j9kg00qf 1104 28 in in IN cord-022526-j9kg00qf 1104 29 inducing induce VBG cord-022526-j9kg00qf 1104 30 ulceration ulceration NN cord-022526-j9kg00qf 1104 31 . . . cord-022526-j9kg00qf 1105 1 Infection infection NN cord-022526-j9kg00qf 1105 2 with with IN cord-022526-j9kg00qf 1105 3 this this DT cord-022526-j9kg00qf 1105 4 organism organism NN cord-022526-j9kg00qf 1105 5 has have VBZ cord-022526-j9kg00qf 1105 6 the the DT cord-022526-j9kg00qf 1105 7 effect effect NN cord-022526-j9kg00qf 1105 8 of of IN cord-022526-j9kg00qf 1105 9 raising raise VBG cord-022526-j9kg00qf 1105 10 gastric gastric JJ cord-022526-j9kg00qf 1105 11 pH ph NN cord-022526-j9kg00qf 1105 12 because because IN cord-022526-j9kg00qf 1105 13 of of IN cord-022526-j9kg00qf 1105 14 disruption disruption NN cord-022526-j9kg00qf 1105 15 of of IN cord-022526-j9kg00qf 1105 16 gastric gastric JJ cord-022526-j9kg00qf 1105 17 glands gland NNS cord-022526-j9kg00qf 1105 18 and and CC cord-022526-j9kg00qf 1105 19 also also RB cord-022526-j9kg00qf 1105 20 induces induce VBZ cord-022526-j9kg00qf 1105 21 an an DT cord-022526-j9kg00qf 1105 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 1105 23 reaction reaction NN cord-022526-j9kg00qf 1105 24 that that WDT cord-022526-j9kg00qf 1105 25 causes cause VBZ cord-022526-j9kg00qf 1105 26 damage damage NN cord-022526-j9kg00qf 1105 27 . . . cord-022526-j9kg00qf 1106 1 49 49 CD cord-022526-j9kg00qf 1107 1 However however RB cord-022526-j9kg00qf 1107 2 , , , cord-022526-j9kg00qf 1107 3 little little JJ cord-022526-j9kg00qf 1107 4 evidence evidence NN cord-022526-j9kg00qf 1107 5 to to IN cord-022526-j9kg00qf 1107 6 date date NN cord-022526-j9kg00qf 1107 7 indicates indicate VBZ cord-022526-j9kg00qf 1107 8 that that IN cord-022526-j9kg00qf 1107 9 this this DT cord-022526-j9kg00qf 1107 10 organism organism NN cord-022526-j9kg00qf 1107 11 is be VBZ cord-022526-j9kg00qf 1107 12 involved involve VBN cord-022526-j9kg00qf 1107 13 in in IN cord-022526-j9kg00qf 1107 14 gastric gastric JJ cord-022526-j9kg00qf 1107 15 ulcers ulcer NNS cord-022526-j9kg00qf 1107 16 in in IN cord-022526-j9kg00qf 1107 17 horses horse NNS cord-022526-j9kg00qf 1107 18 . . . cord-022526-j9kg00qf 1108 1 In in IN cord-022526-j9kg00qf 1108 2 the the DT cord-022526-j9kg00qf 1108 3 absence absence NN cord-022526-j9kg00qf 1108 4 of of IN cord-022526-j9kg00qf 1108 5 a a DT cord-022526-j9kg00qf 1108 6 known know VBN cord-022526-j9kg00qf 1108 7 role role NN cord-022526-j9kg00qf 1108 8 for for IN cord-022526-j9kg00qf 1108 9 infectious infectious JJ cord-022526-j9kg00qf 1108 10 agents agent NNS cord-022526-j9kg00qf 1108 11 in in IN cord-022526-j9kg00qf 1108 12 gastric gastric JJ cord-022526-j9kg00qf 1108 13 ulceration ulceration NN cord-022526-j9kg00qf 1108 14 in in IN cord-022526-j9kg00qf 1108 15 animals animal NNS cord-022526-j9kg00qf 1108 16 , , , cord-022526-j9kg00qf 1108 17 ulceration ulceration NN cord-022526-j9kg00qf 1108 18 likely likely RB cord-022526-j9kg00qf 1108 19 develops develop VBZ cord-022526-j9kg00qf 1108 20 from from IN cord-022526-j9kg00qf 1108 21 injurious injurious JJ cord-022526-j9kg00qf 1108 22 factors factor NNS cord-022526-j9kg00qf 1108 23 similar similar JJ cord-022526-j9kg00qf 1108 24 to to IN cord-022526-j9kg00qf 1108 25 those those DT cord-022526-j9kg00qf 1108 26 found find VBN cord-022526-j9kg00qf 1108 27 in in IN cord-022526-j9kg00qf 1108 28 the the DT cord-022526-j9kg00qf 1108 29 proximal proximal JJ cord-022526-j9kg00qf 1108 30 stomach stomach NN cord-022526-j9kg00qf 1108 31 , , , cord-022526-j9kg00qf 1108 32 including include VBG cord-022526-j9kg00qf 1108 33 gastric gastric JJ cord-022526-j9kg00qf 1108 34 acid acid NN cord-022526-j9kg00qf 1108 35 and and CC cord-022526-j9kg00qf 1108 36 bile bile NN cord-022526-j9kg00qf 1108 37 . . . cord-022526-j9kg00qf 1109 1 However however RB cord-022526-j9kg00qf 1109 2 , , , cord-022526-j9kg00qf 1109 3 some some DT cord-022526-j9kg00qf 1109 4 factors factor NNS cord-022526-j9kg00qf 1109 5 that that WDT cord-022526-j9kg00qf 1109 6 are be VBP cord-022526-j9kg00qf 1109 7 important important JJ cord-022526-j9kg00qf 1109 8 to to IN cord-022526-j9kg00qf 1109 9 induction induction NN cord-022526-j9kg00qf 1109 10 of of IN cord-022526-j9kg00qf 1109 11 squamous squamous JJ cord-022526-j9kg00qf 1109 12 epithelial epithelial JJ cord-022526-j9kg00qf 1109 13 ulceration ulceration NN cord-022526-j9kg00qf 1109 14 may may MD cord-022526-j9kg00qf 1109 15 not not RB cord-022526-j9kg00qf 1109 16 be be VB cord-022526-j9kg00qf 1109 17 important important JJ cord-022526-j9kg00qf 1109 18 in in IN cord-022526-j9kg00qf 1109 19 development development NN cord-022526-j9kg00qf 1109 20 of of IN cord-022526-j9kg00qf 1109 21 proper proper JJ cord-022526-j9kg00qf 1109 22 gastric gastric JJ cord-022526-j9kg00qf 1109 23 mucosal mucosal JJ cord-022526-j9kg00qf 1109 24 ulceration ulceration NN cord-022526-j9kg00qf 1109 25 . . . cord-022526-j9kg00qf 1110 1 For for IN cord-022526-j9kg00qf 1110 2 example example NN cord-022526-j9kg00qf 1110 3 , , , cord-022526-j9kg00qf 1110 4 feed feed VB cord-022526-j9kg00qf 1110 5 deprivation deprivation NN cord-022526-j9kg00qf 1110 6 and and CC cord-022526-j9kg00qf 1110 7 intensive intensive JJ cord-022526-j9kg00qf 1110 8 training training NN cord-022526-j9kg00qf 1110 9 reproducibly reproducibly RB cord-022526-j9kg00qf 1110 10 induce induce VBP cord-022526-j9kg00qf 1110 11 squamous squamous JJ cord-022526-j9kg00qf 1110 12 epithelial epithelial JJ cord-022526-j9kg00qf 1110 13 ulceration ulceration NN cord-022526-j9kg00qf 1110 14 in in IN cord-022526-j9kg00qf 1110 15 horses horse NNS cord-022526-j9kg00qf 1110 16 but but CC cord-022526-j9kg00qf 1110 17 have have VBP cord-022526-j9kg00qf 1110 18 little little JJ cord-022526-j9kg00qf 1110 19 effect effect NN cord-022526-j9kg00qf 1110 20 on on IN cord-022526-j9kg00qf 1110 21 proper proper JJ cord-022526-j9kg00qf 1110 22 gastric gastric JJ cord-022526-j9kg00qf 1110 23 mucosa mucosa NN cord-022526-j9kg00qf 1110 24 in in IN cord-022526-j9kg00qf 1110 25 horses horse NNS cord-022526-j9kg00qf 1110 26 . . . cord-022526-j9kg00qf 1111 1 50 50 CD cord-022526-j9kg00qf 1111 2 Gastric gastric JJ cord-022526-j9kg00qf 1111 3 acid acid NN cord-022526-j9kg00qf 1111 4 likely likely RB cord-022526-j9kg00qf 1111 5 plays play VBZ cord-022526-j9kg00qf 1111 6 a a DT cord-022526-j9kg00qf 1111 7 key key JJ cord-022526-j9kg00qf 1111 8 role role NN cord-022526-j9kg00qf 1111 9 , , , cord-022526-j9kg00qf 1111 10 whereas whereas IN cord-022526-j9kg00qf 1111 11 other other JJ cord-022526-j9kg00qf 1111 12 factors factor NNS cord-022526-j9kg00qf 1111 13 such such JJ cord-022526-j9kg00qf 1111 14 as as IN cord-022526-j9kg00qf 1111 15 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 1111 16 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1111 17 drugs drug NNS cord-022526-j9kg00qf 1111 18 ( ( -LRB- cord-022526-j9kg00qf 1111 19 NSAIDs nsaid NNS cord-022526-j9kg00qf 1111 20 ) ) -RRB- cord-022526-j9kg00qf 1111 21 serve serve VBP cord-022526-j9kg00qf 1111 22 to to TO cord-022526-j9kg00qf 1111 23 reduce reduce VB cord-022526-j9kg00qf 1111 24 gastric gastric JJ cord-022526-j9kg00qf 1111 25 defense defense NN cord-022526-j9kg00qf 1111 26 mechanisms mechanism NNS cord-022526-j9kg00qf 1111 27 . . . cord-022526-j9kg00qf 1112 1 In in IN cord-022526-j9kg00qf 1112 2 particular particular JJ cord-022526-j9kg00qf 1112 3 , , , cord-022526-j9kg00qf 1112 4 inhibition inhibition NN cord-022526-j9kg00qf 1112 5 of of IN cord-022526-j9kg00qf 1112 6 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1112 7 production production NN cord-022526-j9kg00qf 1112 8 reduces reduce VBZ cord-022526-j9kg00qf 1112 9 mucus mucus NN cord-022526-j9kg00qf 1112 10 and and CC cord-022526-j9kg00qf 1112 11 bicarbonate bicarbonate NN cord-022526-j9kg00qf 1112 12 secretion secretion NN cord-022526-j9kg00qf 1112 13 while while IN cord-022526-j9kg00qf 1112 14 also also RB cord-022526-j9kg00qf 1112 15 reducing reduce VBG cord-022526-j9kg00qf 1112 16 gastric gastric JJ cord-022526-j9kg00qf 1112 17 mucosal mucosal JJ cord-022526-j9kg00qf 1112 18 blood blood NN cord-022526-j9kg00qf 1112 19 flow flow NN cord-022526-j9kg00qf 1112 20 . . . cord-022526-j9kg00qf 1113 1 51 51 CD cord-022526-j9kg00qf 1114 1 Some some DT cord-022526-j9kg00qf 1114 2 of of IN cord-022526-j9kg00qf 1114 3 the the DT cord-022526-j9kg00qf 1114 4 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 1114 5 also also RB cord-022526-j9kg00qf 1114 6 have have VBP cord-022526-j9kg00qf 1114 7 a a DT cord-022526-j9kg00qf 1114 8 topical topical JJ cord-022526-j9kg00qf 1114 9 irritant irritant JJ cord-022526-j9kg00qf 1114 10 effect effect NN cord-022526-j9kg00qf 1114 11 , , , cord-022526-j9kg00qf 1114 12 although although IN cord-022526-j9kg00qf 1114 13 this this DT cord-022526-j9kg00qf 1114 14 appears appear VBZ cord-022526-j9kg00qf 1114 15 to to TO cord-022526-j9kg00qf 1114 16 be be VB cord-022526-j9kg00qf 1114 17 of of IN cord-022526-j9kg00qf 1114 18 minor minor JJ cord-022526-j9kg00qf 1114 19 significance significance NN cord-022526-j9kg00qf 1114 20 because because IN cord-022526-j9kg00qf 1114 21 the the DT cord-022526-j9kg00qf 1114 22 route route NN cord-022526-j9kg00qf 1114 23 of of IN cord-022526-j9kg00qf 1114 24 administration administration NN cord-022526-j9kg00qf 1114 25 ( ( -LRB- cord-022526-j9kg00qf 1114 26 oral oral JJ cord-022526-j9kg00qf 1114 27 or or CC cord-022526-j9kg00qf 1114 28 parenteral parenteral JJ cord-022526-j9kg00qf 1114 29 ) ) -RRB- cord-022526-j9kg00qf 1114 30 seems seem VBZ cord-022526-j9kg00qf 1114 31 to to TO cord-022526-j9kg00qf 1114 32 have have VB cord-022526-j9kg00qf 1114 33 little little JJ cord-022526-j9kg00qf 1114 34 influence influence NN cord-022526-j9kg00qf 1114 35 on on IN cord-022526-j9kg00qf 1114 36 development development NN cord-022526-j9kg00qf 1114 37 of of IN cord-022526-j9kg00qf 1114 38 ulceration ulceration NN cord-022526-j9kg00qf 1114 39 . . . cord-022526-j9kg00qf 1115 1 52 52 CD cord-022526-j9kg00qf 1116 1 The the DT cord-022526-j9kg00qf 1116 2 source source NN cord-022526-j9kg00qf 1116 3 of of IN cord-022526-j9kg00qf 1116 4 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1116 5 responsible responsible JJ cord-022526-j9kg00qf 1116 6 for for IN cord-022526-j9kg00qf 1116 7 gastric gastric JJ cord-022526-j9kg00qf 1116 8 protection protection NN cord-022526-j9kg00qf 1116 9 originally originally RB cord-022526-j9kg00qf 1116 10 was be VBD cord-022526-j9kg00qf 1116 11 assumed assume VBN cord-022526-j9kg00qf 1116 12 to to TO cord-022526-j9kg00qf 1116 13 be be VB cord-022526-j9kg00qf 1116 14 cyclooxygenase cyclooxygenase JJ cord-022526-j9kg00qf 1116 15 1 1 CD cord-022526-j9kg00qf 1116 16 ( ( -LRB- cord-022526-j9kg00qf 1116 17 COX-1 COX-1 NNP cord-022526-j9kg00qf 1116 18 ) ) -RRB- cord-022526-j9kg00qf 1116 19 , , , cord-022526-j9kg00qf 1116 20 because because IN cord-022526-j9kg00qf 1116 21 this this DT cord-022526-j9kg00qf 1116 22 isoform isoform NN cord-022526-j9kg00qf 1116 23 is be VBZ cord-022526-j9kg00qf 1116 24 expressed express VBN cord-022526-j9kg00qf 1116 25 constitutively constitutively RB cord-022526-j9kg00qf 1116 26 in in IN cord-022526-j9kg00qf 1116 27 gastric gastric JJ cord-022526-j9kg00qf 1116 28 mucosa mucosa NN cord-022526-j9kg00qf 1116 29 , , , cord-022526-j9kg00qf 1116 30 whereas whereas IN cord-022526-j9kg00qf 1116 31 COX-2 COX-2 NNP cord-022526-j9kg00qf 1116 32 is be VBZ cord-022526-j9kg00qf 1116 33 not not RB cord-022526-j9kg00qf 1116 34 expressed express VBN cord-022526-j9kg00qf 1116 35 in in IN cord-022526-j9kg00qf 1116 36 the the DT cord-022526-j9kg00qf 1116 37 stomach stomach NN cord-022526-j9kg00qf 1116 38 unless unless IN cord-022526-j9kg00qf 1116 39 induced induce VBN cord-022526-j9kg00qf 1116 40 by by IN cord-022526-j9kg00qf 1116 41 inflammatory inflammatory JJ cord-022526-j9kg00qf 1116 42 mediators mediator NNS cord-022526-j9kg00qf 1116 43 . . . cord-022526-j9kg00qf 1117 1 However however RB cord-022526-j9kg00qf 1117 2 , , , cord-022526-j9kg00qf 1117 3 mice mouse NNS cord-022526-j9kg00qf 1117 4 in in IN cord-022526-j9kg00qf 1117 5 which which WDT cord-022526-j9kg00qf 1117 6 the the DT cord-022526-j9kg00qf 1117 7 COX-1 cox-1 JJ cord-022526-j9kg00qf 1117 8 gene gene NN cord-022526-j9kg00qf 1117 9 has have VBZ cord-022526-j9kg00qf 1117 10 been be VBN cord-022526-j9kg00qf 1117 11 knocked knock VBN cord-022526-j9kg00qf 1117 12 out out RP cord-022526-j9kg00qf 1117 13 fail fail VB cord-022526-j9kg00qf 1117 14 to to TO cord-022526-j9kg00qf 1117 15 develop develop VB cord-022526-j9kg00qf 1117 16 spontaneous spontaneous JJ cord-022526-j9kg00qf 1117 17 gastric gastric JJ cord-022526-j9kg00qf 1117 18 lesions lesion NNS cord-022526-j9kg00qf 1117 19 , , , cord-022526-j9kg00qf 1117 20 53 53 CD cord-022526-j9kg00qf 1117 21 possibly possibly RB cord-022526-j9kg00qf 1117 22 because because IN cord-022526-j9kg00qf 1117 23 of of IN cord-022526-j9kg00qf 1117 24 compensatory compensatory JJ cord-022526-j9kg00qf 1117 25 increases increase NNS cord-022526-j9kg00qf 1117 26 in in IN cord-022526-j9kg00qf 1117 27 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1117 28 production production NN cord-022526-j9kg00qf 1117 29 by by IN cord-022526-j9kg00qf 1117 30 COX-2 COX-2 NNP cord-022526-j9kg00qf 1117 31 . . . cord-022526-j9kg00qf 1117 32 54 54 CD cord-022526-j9kg00qf 1118 1 This this DT cord-022526-j9kg00qf 1118 2 concept concept NN cord-022526-j9kg00qf 1118 3 agrees agree VBZ cord-022526-j9kg00qf 1118 4 with with IN cord-022526-j9kg00qf 1118 5 recent recent JJ cord-022526-j9kg00qf 1118 6 data datum NNS cord-022526-j9kg00qf 1118 7 indicating indicate VBG cord-022526-j9kg00qf 1118 8 that that IN cord-022526-j9kg00qf 1118 9 inhibition inhibition NN cord-022526-j9kg00qf 1118 10 of of IN cord-022526-j9kg00qf 1118 11 both both CC cord-022526-j9kg00qf 1118 12 COX COX NNP cord-022526-j9kg00qf 1118 13 isoforms isoform NNS cord-022526-j9kg00qf 1118 14 is be VBZ cord-022526-j9kg00qf 1118 15 required require VBN cord-022526-j9kg00qf 1118 16 to to TO cord-022526-j9kg00qf 1118 17 induce induce VB cord-022526-j9kg00qf 1118 18 gastric gastric JJ cord-022526-j9kg00qf 1118 19 ulceration ulceration NN cord-022526-j9kg00qf 1118 20 . . . cord-022526-j9kg00qf 1119 1 55 55 CD cord-022526-j9kg00qf 1120 1 From from IN cord-022526-j9kg00qf 1120 2 a a DT cord-022526-j9kg00qf 1120 3 clinical clinical JJ cord-022526-j9kg00qf 1120 4 perspective perspective NN cord-022526-j9kg00qf 1120 5 this this DT cord-022526-j9kg00qf 1120 6 data datum NNS cord-022526-j9kg00qf 1120 7 indicate indicate VBP cord-022526-j9kg00qf 1120 8 that that IN cord-022526-j9kg00qf 1120 9 drugs drug NNS cord-022526-j9kg00qf 1120 10 selective selective JJ cord-022526-j9kg00qf 1120 11 for for IN cord-022526-j9kg00qf 1120 12 COX-1 cox-1 JJ cord-022526-j9kg00qf 1120 13 or or CC cord-022526-j9kg00qf 1120 14 COX-2 COX-2 NNP cord-022526-j9kg00qf 1120 15 may may MD cord-022526-j9kg00qf 1120 16 be be VB cord-022526-j9kg00qf 1120 17 less less RBR cord-022526-j9kg00qf 1120 18 ulcerogenic ulcerogenic JJ cord-022526-j9kg00qf 1120 19 in in IN cord-022526-j9kg00qf 1120 20 the the DT cord-022526-j9kg00qf 1120 21 horse horse NN cord-022526-j9kg00qf 1120 22 . . . cord-022526-j9kg00qf 1121 1 Because because IN cord-022526-j9kg00qf 1121 2 COX-2 COX-2 NNP cord-022526-j9kg00qf 1121 3 elaborates elaborate VBZ cord-022526-j9kg00qf 1121 4 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1121 5 induced induce VBN cord-022526-j9kg00qf 1121 6 by by IN cord-022526-j9kg00qf 1121 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 1121 8 stimuli stimulus NNS cord-022526-j9kg00qf 1121 9 , , , cord-022526-j9kg00qf 1121 10 selective selective JJ cord-022526-j9kg00qf 1121 11 inhibitors inhibitor NNS cord-022526-j9kg00qf 1121 12 of of IN cord-022526-j9kg00qf 1121 13 COX-2 COX-2 NNP cord-022526-j9kg00qf 1121 14 may may MD cord-022526-j9kg00qf 1121 15 be be VB cord-022526-j9kg00qf 1121 16 particularly particularly RB cord-022526-j9kg00qf 1121 17 useful useful JJ cord-022526-j9kg00qf 1121 18 because because IN cord-022526-j9kg00qf 1121 19 of of IN cord-022526-j9kg00qf 1121 20 their -PRON- PRP$ cord-022526-j9kg00qf 1121 21 ability ability NN cord-022526-j9kg00qf 1121 22 to to TO cord-022526-j9kg00qf 1121 23 serve serve VB cord-022526-j9kg00qf 1121 24 as as IN cord-022526-j9kg00qf 1121 25 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1121 26 agents agent NNS cord-022526-j9kg00qf 1121 27 that that WDT cord-022526-j9kg00qf 1121 28 are be VBP cord-022526-j9kg00qf 1121 29 less less RBR cord-022526-j9kg00qf 1121 30 ulcerogenic ulcerogenic JJ cord-022526-j9kg00qf 1121 31 . . . cord-022526-j9kg00qf 1122 1 56 56 CD cord-022526-j9kg00qf 1123 1 The the DT cord-022526-j9kg00qf 1123 2 most most RBS cord-022526-j9kg00qf 1123 3 notable notable JJ cord-022526-j9kg00qf 1123 4 cause cause NN cord-022526-j9kg00qf 1123 5 of of IN cord-022526-j9kg00qf 1123 6 intestinal intestinal JJ cord-022526-j9kg00qf 1123 7 mucosal mucosal JJ cord-022526-j9kg00qf 1123 8 injury injury NN cord-022526-j9kg00qf 1123 9 in in IN cord-022526-j9kg00qf 1123 10 horses horse NNS cord-022526-j9kg00qf 1123 11 , , , cord-022526-j9kg00qf 1123 12 particularly particularly RB cord-022526-j9kg00qf 1123 13 those those DT cord-022526-j9kg00qf 1123 14 suffering suffer VBG cord-022526-j9kg00qf 1123 15 from from IN cord-022526-j9kg00qf 1123 16 colic colic NN cord-022526-j9kg00qf 1123 17 , , , cord-022526-j9kg00qf 1123 18 is be VBZ cord-022526-j9kg00qf 1123 19 ischemia ischemia NN cord-022526-j9kg00qf 1123 20 . . . cord-022526-j9kg00qf 1124 1 Initially initially RB cord-022526-j9kg00qf 1124 2 , , , cord-022526-j9kg00qf 1124 3 that that IN cord-022526-j9kg00qf 1124 4 a a DT cord-022526-j9kg00qf 1124 5 reduction reduction NN cord-022526-j9kg00qf 1124 6 in in IN cord-022526-j9kg00qf 1124 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1124 8 blood blood NN cord-022526-j9kg00qf 1124 9 supply supply NN cord-022526-j9kg00qf 1124 10 leads lead VBZ cord-022526-j9kg00qf 1124 11 to to IN cord-022526-j9kg00qf 1124 12 mucosal mucosal JJ cord-022526-j9kg00qf 1124 13 injury injury NN cord-022526-j9kg00qf 1124 14 seems seem VBZ cord-022526-j9kg00qf 1124 15 intuitive intuitive JJ cord-022526-j9kg00qf 1124 16 . . . cord-022526-j9kg00qf 1125 1 However however RB cord-022526-j9kg00qf 1125 2 , , , cord-022526-j9kg00qf 1125 3 the the DT cord-022526-j9kg00qf 1125 4 anatomy anatomy NN cord-022526-j9kg00qf 1125 5 of of IN cord-022526-j9kg00qf 1125 6 the the DT cord-022526-j9kg00qf 1125 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1125 8 tract tract NN cord-022526-j9kg00qf 1125 9 and and CC cord-022526-j9kg00qf 1125 10 the the DT cord-022526-j9kg00qf 1125 11 differing differ VBG cord-022526-j9kg00qf 1125 12 structure structure NN cord-022526-j9kg00qf 1125 13 of of IN cord-022526-j9kg00qf 1125 14 the the DT cord-022526-j9kg00qf 1125 15 intestinal intestinal JJ cord-022526-j9kg00qf 1125 16 mucosa mucosa NN cord-022526-j9kg00qf 1125 17 at at IN cord-022526-j9kg00qf 1125 18 various various JJ cord-022526-j9kg00qf 1125 19 anatomic anatomic JJ cord-022526-j9kg00qf 1125 20 locations location NNS cord-022526-j9kg00qf 1125 21 have have VBP cord-022526-j9kg00qf 1125 22 a a DT cord-022526-j9kg00qf 1125 23 significant significant JJ cord-022526-j9kg00qf 1125 24 influence influence NN cord-022526-j9kg00qf 1125 25 on on IN cord-022526-j9kg00qf 1125 26 the the DT cord-022526-j9kg00qf 1125 27 extent extent NN cord-022526-j9kg00qf 1125 28 of of IN cord-022526-j9kg00qf 1125 29 mucosal mucosal JJ cord-022526-j9kg00qf 1125 30 injury injury NN cord-022526-j9kg00qf 1125 31 . . . cord-022526-j9kg00qf 1126 1 Furthermore furthermore RB cord-022526-j9kg00qf 1126 2 , , , cord-022526-j9kg00qf 1126 3 ischemic ischemic JJ cord-022526-j9kg00qf 1126 4 injury injury NN cord-022526-j9kg00qf 1126 5 may may MD cord-022526-j9kg00qf 1126 6 be be VB cord-022526-j9kg00qf 1126 7 induced induce VBN cord-022526-j9kg00qf 1126 8 by by IN cord-022526-j9kg00qf 1126 9 several several JJ cord-022526-j9kg00qf 1126 10 different different JJ cord-022526-j9kg00qf 1126 11 mechanisms mechanism NNS cord-022526-j9kg00qf 1126 12 , , , cord-022526-j9kg00qf 1126 13 including include VBG cord-022526-j9kg00qf 1126 14 occlusion occlusion NN cord-022526-j9kg00qf 1126 15 of of IN cord-022526-j9kg00qf 1126 16 arterial arterial JJ cord-022526-j9kg00qf 1126 17 supply supply NN cord-022526-j9kg00qf 1126 18 by by IN cord-022526-j9kg00qf 1126 19 a a DT cord-022526-j9kg00qf 1126 20 thrombus thrombus NN cord-022526-j9kg00qf 1126 21 , , , cord-022526-j9kg00qf 1126 22 strangulation strangulation NN cord-022526-j9kg00qf 1126 23 of of IN cord-022526-j9kg00qf 1126 24 intestinal intestinal JJ cord-022526-j9kg00qf 1126 25 vasculature vasculature NN cord-022526-j9kg00qf 1126 26 , , , cord-022526-j9kg00qf 1126 27 and and CC cord-022526-j9kg00qf 1126 28 generalized generalized JJ cord-022526-j9kg00qf 1126 29 reduction reduction NN cord-022526-j9kg00qf 1126 30 in in IN cord-022526-j9kg00qf 1126 31 blood blood NN cord-022526-j9kg00qf 1126 32 flow flow NN cord-022526-j9kg00qf 1126 33 associated associate VBN cord-022526-j9kg00qf 1126 34 with with IN cord-022526-j9kg00qf 1126 35 various various JJ cord-022526-j9kg00qf 1126 36 shock shock NN cord-022526-j9kg00qf 1126 37 states state NNS cord-022526-j9kg00qf 1126 38 . . . cord-022526-j9kg00qf 1127 1 In in IN cord-022526-j9kg00qf 1127 2 addition addition NN cord-022526-j9kg00qf 1127 3 , , , cord-022526-j9kg00qf 1127 4 a a DT cord-022526-j9kg00qf 1127 5 number number NN cord-022526-j9kg00qf 1127 6 of of IN cord-022526-j9kg00qf 1127 7 seemingly seemingly RB cord-022526-j9kg00qf 1127 8 distinct distinct JJ cord-022526-j9kg00qf 1127 9 mechanisms mechanism NNS cord-022526-j9kg00qf 1127 10 of of IN cord-022526-j9kg00qf 1127 11 intestinal intestinal JJ cord-022526-j9kg00qf 1127 12 injury injury NN cord-022526-j9kg00qf 1127 13 , , , cord-022526-j9kg00qf 1127 14 such such JJ cord-022526-j9kg00qf 1127 15 as as IN cord-022526-j9kg00qf 1127 16 intestinal intestinal JJ cord-022526-j9kg00qf 1127 17 distention distention NN cord-022526-j9kg00qf 1127 18 , , , cord-022526-j9kg00qf 1127 19 also also RB cord-022526-j9kg00qf 1127 20 trigger trigger VB cord-022526-j9kg00qf 1127 21 mucosal mucosal JJ cord-022526-j9kg00qf 1127 22 injury injury NN cord-022526-j9kg00qf 1127 23 via via IN cord-022526-j9kg00qf 1127 24 an an DT cord-022526-j9kg00qf 1127 25 ischemic ischemic JJ cord-022526-j9kg00qf 1127 26 mechanism mechanism NN cord-022526-j9kg00qf 1127 27 . . . cord-022526-j9kg00qf 1128 1 Finally finally RB cord-022526-j9kg00qf 1128 2 , , , cord-022526-j9kg00qf 1128 3 reperfusion reperfusion NN cord-022526-j9kg00qf 1128 4 injury injury NN cord-022526-j9kg00qf 1128 5 also also RB cord-022526-j9kg00qf 1128 6 may may MD cord-022526-j9kg00qf 1128 7 influence influence VB cord-022526-j9kg00qf 1128 8 the the DT cord-022526-j9kg00qf 1128 9 extent extent NN cord-022526-j9kg00qf 1128 10 of of IN cord-022526-j9kg00qf 1128 11 mucosal mucosal JJ cord-022526-j9kg00qf 1128 12 injury injury NN cord-022526-j9kg00qf 1128 13 following follow VBG cord-022526-j9kg00qf 1128 14 an an DT cord-022526-j9kg00qf 1128 15 ischemic ischemic JJ cord-022526-j9kg00qf 1128 16 episode episode NN cord-022526-j9kg00qf 1128 17 and and CC cord-022526-j9kg00qf 1128 18 has have VBZ cord-022526-j9kg00qf 1128 19 been be VBN cord-022526-j9kg00qf 1128 20 proposed propose VBN cord-022526-j9kg00qf 1128 21 as as IN cord-022526-j9kg00qf 1128 22 a a DT cord-022526-j9kg00qf 1128 23 potential potential JJ cord-022526-j9kg00qf 1128 24 site site NN cord-022526-j9kg00qf 1128 25 of of IN cord-022526-j9kg00qf 1128 26 therapeutic therapeutic JJ cord-022526-j9kg00qf 1128 27 intervention intervention NN cord-022526-j9kg00qf 1128 28 . . . cord-022526-j9kg00qf 1129 1 57 57 CD cord-022526-j9kg00qf 1129 2 , , , cord-022526-j9kg00qf 1129 3 58 58 CD cord-022526-j9kg00qf 1130 1 Thus thus RB cord-022526-j9kg00qf 1130 2 understanding understand VBG cord-022526-j9kg00qf 1130 3 the the DT cord-022526-j9kg00qf 1130 4 mechanisms mechanism NNS cord-022526-j9kg00qf 1130 5 of of IN cord-022526-j9kg00qf 1130 6 ischemia ischemia NN cord-022526-j9kg00qf 1130 7 - - HYPH cord-022526-j9kg00qf 1130 8 reperfusion reperfusion NN cord-022526-j9kg00qf 1130 9 injury injury NN cord-022526-j9kg00qf 1130 10 is be VBZ cord-022526-j9kg00qf 1130 11 critical critical JJ cord-022526-j9kg00qf 1130 12 to to IN cord-022526-j9kg00qf 1130 13 developing develop VBG cord-022526-j9kg00qf 1130 14 an an DT cord-022526-j9kg00qf 1130 15 understanding understanding NN cord-022526-j9kg00qf 1130 16 of of IN cord-022526-j9kg00qf 1130 17 the the DT cord-022526-j9kg00qf 1130 18 severity severity NN cord-022526-j9kg00qf 1130 19 of of IN cord-022526-j9kg00qf 1130 20 various various JJ cord-022526-j9kg00qf 1130 21 clinical clinical JJ cord-022526-j9kg00qf 1130 22 conditions condition NNS cord-022526-j9kg00qf 1130 23 and and CC cord-022526-j9kg00qf 1130 24 beginning begin VBG cord-022526-j9kg00qf 1130 25 to to TO cord-022526-j9kg00qf 1130 26 formulate formulate VB cord-022526-j9kg00qf 1130 27 a a DT cord-022526-j9kg00qf 1130 28 therapeutic therapeutic JJ cord-022526-j9kg00qf 1130 29 approach approach NN cord-022526-j9kg00qf 1130 30 to to IN cord-022526-j9kg00qf 1130 31 diseases disease NNS cord-022526-j9kg00qf 1130 32 characterized characterize VBN cord-022526-j9kg00qf 1130 33 by by IN cord-022526-j9kg00qf 1130 34 this this DT cord-022526-j9kg00qf 1130 35 devastating devastating JJ cord-022526-j9kg00qf 1130 36 form form NN cord-022526-j9kg00qf 1130 37 of of IN cord-022526-j9kg00qf 1130 38 injury injury NN cord-022526-j9kg00qf 1130 39 . . . cord-022526-j9kg00qf 1131 1 The the DT cord-022526-j9kg00qf 1131 2 intestinal intestinal JJ cord-022526-j9kg00qf 1131 3 circulation circulation NN cord-022526-j9kg00qf 1131 4 is be VBZ cord-022526-j9kg00qf 1131 5 capable capable JJ cord-022526-j9kg00qf 1131 6 of of IN cord-022526-j9kg00qf 1131 7 closely closely RB cord-022526-j9kg00qf 1131 8 regulating regulate VBG cord-022526-j9kg00qf 1131 9 blood blood NN cord-022526-j9kg00qf 1131 10 flow flow NN cord-022526-j9kg00qf 1131 11 during during IN cord-022526-j9kg00qf 1131 12 periods period NNS cord-022526-j9kg00qf 1131 13 of of IN cord-022526-j9kg00qf 1131 14 low low JJ cord-022526-j9kg00qf 1131 15 systemic systemic JJ cord-022526-j9kg00qf 1131 16 perfusion perfusion NN cord-022526-j9kg00qf 1131 17 pressure pressure NN cord-022526-j9kg00qf 1131 18 . . . cord-022526-j9kg00qf 1132 1 59 59 CD cord-022526-j9kg00qf 1132 2 , , , cord-022526-j9kg00qf 1132 3 60 60 CD cord-022526-j9kg00qf 1132 4 In in IN cord-022526-j9kg00qf 1132 5 particular particular JJ cord-022526-j9kg00qf 1132 6 , , , cord-022526-j9kg00qf 1132 7 local local JJ cord-022526-j9kg00qf 1132 8 regulation regulation NN cord-022526-j9kg00qf 1132 9 of of IN cord-022526-j9kg00qf 1132 10 resistance resistance NN cord-022526-j9kg00qf 1132 11 vessels vessel NNS cord-022526-j9kg00qf 1132 12 within within IN cord-022526-j9kg00qf 1132 13 the the DT cord-022526-j9kg00qf 1132 14 microvasculature microvasculature NN cord-022526-j9kg00qf 1132 15 is be VBZ cord-022526-j9kg00qf 1132 16 particularly particularly RB cord-022526-j9kg00qf 1132 17 prominent prominent JJ cord-022526-j9kg00qf 1132 18 , , , cord-022526-j9kg00qf 1132 19 whereby whereby WRB cord-022526-j9kg00qf 1132 20 metabolic metabolic JJ cord-022526-j9kg00qf 1132 21 end end NN cord-022526-j9kg00qf 1132 22 products product NNS cord-022526-j9kg00qf 1132 23 of of IN cord-022526-j9kg00qf 1132 24 adenosine adenosine NN cord-022526-j9kg00qf 1132 25 triphosphate triphosphate NN cord-022526-j9kg00qf 1132 26 ( ( -LRB- cord-022526-j9kg00qf 1132 27 ATP ATP NNP cord-022526-j9kg00qf 1132 28 ) ) -RRB- cord-022526-j9kg00qf 1132 29 result result VBP cord-022526-j9kg00qf 1132 30 in in IN cord-022526-j9kg00qf 1132 31 continued continued JJ cord-022526-j9kg00qf 1132 32 dilation dilation NN cord-022526-j9kg00qf 1132 33 of of IN cord-022526-j9kg00qf 1132 34 resistance resistance NN cord-022526-j9kg00qf 1132 35 vessels vessel NNS cord-022526-j9kg00qf 1132 36 despite despite IN cord-022526-j9kg00qf 1132 37 reductions reduction NNS cord-022526-j9kg00qf 1132 38 in in IN cord-022526-j9kg00qf 1132 39 systemic systemic JJ cord-022526-j9kg00qf 1132 40 arterial arterial JJ cord-022526-j9kg00qf 1132 41 pressure pressure NN cord-022526-j9kg00qf 1132 42 . . . cord-022526-j9kg00qf 1133 1 Dilation dilation NN cord-022526-j9kg00qf 1133 2 results result NNS cord-022526-j9kg00qf 1133 3 in in IN cord-022526-j9kg00qf 1133 4 continued continued JJ cord-022526-j9kg00qf 1133 5 perfusion perfusion NN cord-022526-j9kg00qf 1133 6 of of IN cord-022526-j9kg00qf 1133 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1133 8 tissues tissue NNS cord-022526-j9kg00qf 1133 9 during during IN cord-022526-j9kg00qf 1133 10 the the DT cord-022526-j9kg00qf 1133 11 early early JJ cord-022526-j9kg00qf 1133 12 stages stage NNS cord-022526-j9kg00qf 1133 13 of of IN cord-022526-j9kg00qf 1133 14 shock shock NN cord-022526-j9kg00qf 1133 15 , , , cord-022526-j9kg00qf 1133 16 while while IN cord-022526-j9kg00qf 1133 17 other other JJ cord-022526-j9kg00qf 1133 18 organs organ NNS cord-022526-j9kg00qf 1133 19 such such JJ cord-022526-j9kg00qf 1133 20 as as IN cord-022526-j9kg00qf 1133 21 skeletal skeletal JJ cord-022526-j9kg00qf 1133 22 muscle muscle NN cord-022526-j9kg00qf 1133 23 undergo undergo VBP cord-022526-j9kg00qf 1133 24 massive massive JJ cord-022526-j9kg00qf 1133 25 shunting shunting NN cord-022526-j9kg00qf 1133 26 of of IN cord-022526-j9kg00qf 1133 27 blood blood NN cord-022526-j9kg00qf 1133 28 resulting result VBG cord-022526-j9kg00qf 1133 29 from from IN cord-022526-j9kg00qf 1133 30 increased increase VBN cord-022526-j9kg00qf 1133 31 constriction constriction NN cord-022526-j9kg00qf 1133 32 of of IN cord-022526-j9kg00qf 1133 33 resistance resistance NN cord-022526-j9kg00qf 1133 34 vessels vessel NNS cord-022526-j9kg00qf 1133 35 . . . cord-022526-j9kg00qf 1134 1 The the DT cord-022526-j9kg00qf 1134 2 reasons reason NNS cord-022526-j9kg00qf 1134 3 for for IN cord-022526-j9kg00qf 1134 4 these these DT cord-022526-j9kg00qf 1134 5 differences difference NNS cord-022526-j9kg00qf 1134 6 in in IN cord-022526-j9kg00qf 1134 7 regulation regulation NN cord-022526-j9kg00qf 1134 8 are be VBP cord-022526-j9kg00qf 1134 9 not not RB cord-022526-j9kg00qf 1134 10 entirely entirely RB cord-022526-j9kg00qf 1134 11 clear clear JJ cord-022526-j9kg00qf 1134 12 but but CC cord-022526-j9kg00qf 1134 13 may may MD cord-022526-j9kg00qf 1134 14 relate relate VB cord-022526-j9kg00qf 1134 15 to to IN cord-022526-j9kg00qf 1134 16 the the DT cord-022526-j9kg00qf 1134 17 high high JJ cord-022526-j9kg00qf 1134 18 level level NN cord-022526-j9kg00qf 1134 19 of of IN cord-022526-j9kg00qf 1134 20 energy energy NN cord-022526-j9kg00qf 1134 21 required require VBN cord-022526-j9kg00qf 1134 22 to to TO cord-022526-j9kg00qf 1134 23 fuel fuel VB cord-022526-j9kg00qf 1134 24 the the DT cord-022526-j9kg00qf 1134 25 intestinal intestinal JJ cord-022526-j9kg00qf 1134 26 mucosa mucosa NN cord-022526-j9kg00qf 1134 27 and and CC cord-022526-j9kg00qf 1134 28 the the DT cord-022526-j9kg00qf 1134 29 serious serious JJ cord-022526-j9kg00qf 1134 30 systemic systemic JJ cord-022526-j9kg00qf 1134 31 effects effect NNS cord-022526-j9kg00qf 1134 32 of of IN cord-022526-j9kg00qf 1134 33 breaches breach NNS cord-022526-j9kg00qf 1134 34 in in IN cord-022526-j9kg00qf 1134 35 the the DT cord-022526-j9kg00qf 1134 36 mucosal mucosal JJ cord-022526-j9kg00qf 1134 37 barrier barrier NN cord-022526-j9kg00qf 1134 38 . . . cord-022526-j9kg00qf 1135 1 However however RB cord-022526-j9kg00qf 1135 2 , , , cord-022526-j9kg00qf 1135 3 as as IN cord-022526-j9kg00qf 1135 4 blood blood NN cord-022526-j9kg00qf 1135 5 flow flow NN cord-022526-j9kg00qf 1135 6 falls fall VBZ cord-022526-j9kg00qf 1135 7 below below IN cord-022526-j9kg00qf 1135 8 a a DT cord-022526-j9kg00qf 1135 9 critical critical JJ cord-022526-j9kg00qf 1135 10 level level NN cord-022526-j9kg00qf 1135 11 , , , cord-022526-j9kg00qf 1135 12 regulatory regulatory JJ cord-022526-j9kg00qf 1135 13 systems system NNS cord-022526-j9kg00qf 1135 14 are be VBP cord-022526-j9kg00qf 1135 15 no no RB cord-022526-j9kg00qf 1135 16 longer long RBR cord-022526-j9kg00qf 1135 17 effective effective JJ cord-022526-j9kg00qf 1135 18 and and CC cord-022526-j9kg00qf 1135 19 oxygen oxygen NN cord-022526-j9kg00qf 1135 20 uptake uptake NN cord-022526-j9kg00qf 1135 21 by by IN cord-022526-j9kg00qf 1135 22 the the DT cord-022526-j9kg00qf 1135 23 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1135 24 tissue tissue NN cord-022526-j9kg00qf 1135 25 decreases decrease NNS cord-022526-j9kg00qf 1135 26 , , , cord-022526-j9kg00qf 1135 27 culminating culminate VBG cord-022526-j9kg00qf 1135 28 in in IN cord-022526-j9kg00qf 1135 29 tissue tissue NN cord-022526-j9kg00qf 1135 30 damage damage NN cord-022526-j9kg00qf 1135 31 . . . cord-022526-j9kg00qf 1136 1 59 59 CD cord-022526-j9kg00qf 1137 1 The the DT cord-022526-j9kg00qf 1137 2 tip tip NN cord-022526-j9kg00qf 1137 3 of of IN cord-022526-j9kg00qf 1137 4 the the DT cord-022526-j9kg00qf 1137 5 villus villus NN cord-022526-j9kg00qf 1137 6 is be VBZ cord-022526-j9kg00qf 1137 7 the the DT cord-022526-j9kg00qf 1137 8 most most RBS cord-022526-j9kg00qf 1137 9 susceptible susceptible JJ cord-022526-j9kg00qf 1137 10 region region NN cord-022526-j9kg00qf 1137 11 affected affect VBN cord-022526-j9kg00qf 1137 12 by by IN cord-022526-j9kg00qf 1137 13 hypoxia hypoxia NN cord-022526-j9kg00qf 1137 14 in in IN cord-022526-j9kg00qf 1137 15 the the DT cord-022526-j9kg00qf 1137 16 equine equine JJ cord-022526-j9kg00qf 1137 17 small small JJ cord-022526-j9kg00qf 1137 18 intestine intestine NN cord-022526-j9kg00qf 1137 19 , , , cord-022526-j9kg00qf 1137 20 largely largely RB cord-022526-j9kg00qf 1137 21 because because IN cord-022526-j9kg00qf 1137 22 of of IN cord-022526-j9kg00qf 1137 23 the the DT cord-022526-j9kg00qf 1137 24 countercurrent countercurrent JJ cord-022526-j9kg00qf 1137 25 exchange exchange NN cord-022526-j9kg00qf 1137 26 mechanism mechanism NN cord-022526-j9kg00qf 1137 27 of of IN cord-022526-j9kg00qf 1137 28 blood blood NN cord-022526-j9kg00qf 1137 29 flow flow NN cord-022526-j9kg00qf 1137 30 in in IN cord-022526-j9kg00qf 1137 31 the the DT cord-022526-j9kg00qf 1137 32 small small JJ cord-022526-j9kg00qf 1137 33 intestinal intestinal JJ cord-022526-j9kg00qf 1137 34 villus villus NN cord-022526-j9kg00qf 1137 35 . . . cord-022526-j9kg00qf 1138 1 59 59 CD cord-022526-j9kg00qf 1139 1 This this DT cord-022526-j9kg00qf 1139 2 countercurrent countercurrent NN cord-022526-j9kg00qf 1139 3 exchange exchange NN cord-022526-j9kg00qf 1139 4 mechanism mechanism NN cord-022526-j9kg00qf 1139 5 is be VBZ cord-022526-j9kg00qf 1139 6 attributable attributable JJ cord-022526-j9kg00qf 1139 7 to to IN cord-022526-j9kg00qf 1139 8 the the DT cord-022526-j9kg00qf 1139 9 vascular vascular JJ cord-022526-j9kg00qf 1139 10 architecture architecture NN cord-022526-j9kg00qf 1139 11 , , , cord-022526-j9kg00qf 1139 12 which which WDT cord-022526-j9kg00qf 1139 13 consists consist VBZ cord-022526-j9kg00qf 1139 14 of of IN cord-022526-j9kg00qf 1139 15 a a DT cord-022526-j9kg00qf 1139 16 central central JJ cord-022526-j9kg00qf 1139 17 arteriole arteriole NN cord-022526-j9kg00qf 1139 18 that that IN cord-022526-j9kg00qf 1139 19 courses course VBZ cord-022526-j9kg00qf 1139 20 up up RP cord-022526-j9kg00qf 1139 21 the the DT cord-022526-j9kg00qf 1139 22 core core NN cord-022526-j9kg00qf 1139 23 of of IN cord-022526-j9kg00qf 1139 24 the the DT cord-022526-j9kg00qf 1139 25 villus villus NN cord-022526-j9kg00qf 1139 26 , , , cord-022526-j9kg00qf 1139 27 arborizes arborize NNS cord-022526-j9kg00qf 1139 28 at at IN cord-022526-j9kg00qf 1139 29 the the DT cord-022526-j9kg00qf 1139 30 tip tip NN cord-022526-j9kg00qf 1139 31 , , , cord-022526-j9kg00qf 1139 32 and and CC cord-022526-j9kg00qf 1139 33 is be VBZ cord-022526-j9kg00qf 1139 34 drained drain VBN cord-022526-j9kg00qf 1139 35 by by IN cord-022526-j9kg00qf 1139 36 venules venule NNS cord-022526-j9kg00qf 1139 37 coursing course VBG cord-022526-j9kg00qf 1139 38 down down IN cord-022526-j9kg00qf 1139 39 the the DT cord-022526-j9kg00qf 1139 40 periphery periphery NN cord-022526-j9kg00qf 1139 41 of of IN cord-022526-j9kg00qf 1139 42 the the DT cord-022526-j9kg00qf 1139 43 villus villus NN cord-022526-j9kg00qf 1139 44 . . . cord-022526-j9kg00qf 1140 1 61 61 CD cord-022526-j9kg00qf 1141 1 As as IN cord-022526-j9kg00qf 1141 2 oxygenated oxygenated JJ cord-022526-j9kg00qf 1141 3 blood blood NN cord-022526-j9kg00qf 1141 4 flows flow VBZ cord-022526-j9kg00qf 1141 5 into into IN cord-022526-j9kg00qf 1141 6 the the DT cord-022526-j9kg00qf 1141 7 central central JJ cord-022526-j9kg00qf 1141 8 arteriole arteriole NN cord-022526-j9kg00qf 1141 9 , , , cord-022526-j9kg00qf 1141 10 oxygen oxygen NN cord-022526-j9kg00qf 1141 11 tends tend VBZ cord-022526-j9kg00qf 1141 12 to to TO cord-022526-j9kg00qf 1141 13 diffuse diffuse VB cord-022526-j9kg00qf 1141 14 across across IN cord-022526-j9kg00qf 1141 15 to to IN cord-022526-j9kg00qf 1141 16 the the DT cord-022526-j9kg00qf 1141 17 adjacent adjacent JJ cord-022526-j9kg00qf 1141 18 venules venule NNS cord-022526-j9kg00qf 1141 19 , , , cord-022526-j9kg00qf 1141 20 which which WDT cord-022526-j9kg00qf 1141 21 flow flow VBP cord-022526-j9kg00qf 1141 22 in in IN cord-022526-j9kg00qf 1141 23 the the DT cord-022526-j9kg00qf 1141 24 opposite opposite JJ cord-022526-j9kg00qf 1141 25 direction direction NN cord-022526-j9kg00qf 1141 26 . . . cord-022526-j9kg00qf 1142 1 This this DT cord-022526-j9kg00qf 1142 2 series series NN cord-022526-j9kg00qf 1142 3 of of IN cord-022526-j9kg00qf 1142 4 events event NNS cord-022526-j9kg00qf 1142 5 takes take VBZ cord-022526-j9kg00qf 1142 6 place place NN cord-022526-j9kg00qf 1142 7 along along IN cord-022526-j9kg00qf 1142 8 the the DT cord-022526-j9kg00qf 1142 9 length length NN cord-022526-j9kg00qf 1142 10 of of IN cord-022526-j9kg00qf 1142 11 the the DT cord-022526-j9kg00qf 1142 12 villus villus NN cord-022526-j9kg00qf 1142 13 , , , cord-022526-j9kg00qf 1142 14 resulting result VBG cord-022526-j9kg00qf 1142 15 in in IN cord-022526-j9kg00qf 1142 16 a a DT cord-022526-j9kg00qf 1142 17 tip tip NN cord-022526-j9kg00qf 1142 18 of of IN cord-022526-j9kg00qf 1142 19 the the DT cord-022526-j9kg00qf 1142 20 villus villus NN cord-022526-j9kg00qf 1142 21 that that WDT cord-022526-j9kg00qf 1142 22 is be VBZ cord-022526-j9kg00qf 1142 23 hypoxic hypoxic JJ cord-022526-j9kg00qf 1142 24 even even RB cord-022526-j9kg00qf 1142 25 under under IN cord-022526-j9kg00qf 1142 26 normal normal JJ cord-022526-j9kg00qf 1142 27 conditions condition NNS cord-022526-j9kg00qf 1142 28 . . . cord-022526-j9kg00qf 1143 1 Furthermore furthermore RB cord-022526-j9kg00qf 1143 2 , , , cord-022526-j9kg00qf 1143 3 reduced reduce VBN cord-022526-j9kg00qf 1143 4 blood blood NN cord-022526-j9kg00qf 1143 5 flow flow NN cord-022526-j9kg00qf 1143 6 as as IN cord-022526-j9kg00qf 1143 7 occurs occur VBZ cord-022526-j9kg00qf 1143 8 in in IN cord-022526-j9kg00qf 1143 9 shock shock NN cord-022526-j9kg00qf 1143 10 exacerbates exacerbate VBZ cord-022526-j9kg00qf 1143 11 the the DT cord-022526-j9kg00qf 1143 12 countercurrent countercurrent JJ cord-022526-j9kg00qf 1143 13 exchange exchange NN cord-022526-j9kg00qf 1143 14 of of IN cord-022526-j9kg00qf 1143 15 oxygen oxygen NN cord-022526-j9kg00qf 1143 16 , , , cord-022526-j9kg00qf 1143 17 and and CC cord-022526-j9kg00qf 1143 18 the the DT cord-022526-j9kg00qf 1143 19 tip tip NN cord-022526-j9kg00qf 1143 20 becomes become VBZ cord-022526-j9kg00qf 1143 21 absolutely absolutely RB cord-022526-j9kg00qf 1143 22 hypoxic hypoxic JJ cord-022526-j9kg00qf 1143 23 . . . cord-022526-j9kg00qf 1144 1 59 59 CD cord-022526-j9kg00qf 1145 1 This this DT cord-022526-j9kg00qf 1145 2 mechanism mechanism NN cord-022526-j9kg00qf 1145 3 might may MD cord-022526-j9kg00qf 1145 4 explain explain VB cord-022526-j9kg00qf 1145 5 why why WRB cord-022526-j9kg00qf 1145 6 the the DT cord-022526-j9kg00qf 1145 7 small small JJ cord-022526-j9kg00qf 1145 8 intestinal intestinal JJ cord-022526-j9kg00qf 1145 9 mucosa mucosa NN cord-022526-j9kg00qf 1145 10 is be VBZ cord-022526-j9kg00qf 1145 11 more more RBR cord-022526-j9kg00qf 1145 12 susceptible susceptible JJ cord-022526-j9kg00qf 1145 13 to to IN cord-022526-j9kg00qf 1145 14 ischemic ischemic JJ cord-022526-j9kg00qf 1145 15 injury injury NN cord-022526-j9kg00qf 1145 16 , , , cord-022526-j9kg00qf 1145 17 compared compare VBN cord-022526-j9kg00qf 1145 18 with with IN cord-022526-j9kg00qf 1145 19 the the DT cord-022526-j9kg00qf 1145 20 colon colon NN cord-022526-j9kg00qf 1145 21 , , , cord-022526-j9kg00qf 1145 22 which which WDT cord-022526-j9kg00qf 1145 23 has have VBZ cord-022526-j9kg00qf 1145 24 no no DT cord-022526-j9kg00qf 1145 25 villi villi NN cord-022526-j9kg00qf 1145 26 . . . cord-022526-j9kg00qf 1146 1 For for IN cord-022526-j9kg00qf 1146 2 example example NN cord-022526-j9kg00qf 1146 3 , , , cord-022526-j9kg00qf 1146 4 the the DT cord-022526-j9kg00qf 1146 5 duration duration NN cord-022526-j9kg00qf 1146 6 required require VBN cord-022526-j9kg00qf 1146 7 to to TO cord-022526-j9kg00qf 1146 8 produce produce VB cord-022526-j9kg00qf 1146 9 severe severe JJ cord-022526-j9kg00qf 1146 10 morphologic morphologic JJ cord-022526-j9kg00qf 1146 11 damage damage NN cord-022526-j9kg00qf 1146 12 to to IN cord-022526-j9kg00qf 1146 13 the the DT cord-022526-j9kg00qf 1146 14 equine equine JJ cord-022526-j9kg00qf 1146 15 colon colon NN cord-022526-j9kg00qf 1146 16 is be VBZ cord-022526-j9kg00qf 1146 17 approximately approximately RB cord-022526-j9kg00qf 1146 18 25 25 CD cord-022526-j9kg00qf 1146 19 % % NN cord-022526-j9kg00qf 1146 20 longer long JJR cord-022526-j9kg00qf 1146 21 than than IN cord-022526-j9kg00qf 1146 22 in in IN cord-022526-j9kg00qf 1146 23 the the DT cord-022526-j9kg00qf 1146 24 small small JJ cord-022526-j9kg00qf 1146 25 intestine intestine NN cord-022526-j9kg00qf 1146 26 . . . cord-022526-j9kg00qf 1147 1 62 62 CD cord-022526-j9kg00qf 1147 2 Intestinal intestinal JJ cord-022526-j9kg00qf 1147 3 mucosal mucosal JJ cord-022526-j9kg00qf 1147 4 epithelium epithelium NN cord-022526-j9kg00qf 1147 5 is be VBZ cord-022526-j9kg00qf 1147 6 susceptible susceptible JJ cord-022526-j9kg00qf 1147 7 to to IN cord-022526-j9kg00qf 1147 8 hypoxia hypoxia NN cord-022526-j9kg00qf 1147 9 because because IN cord-022526-j9kg00qf 1147 10 of of IN cord-022526-j9kg00qf 1147 11 the the DT cord-022526-j9kg00qf 1147 12 high high JJ cord-022526-j9kg00qf 1147 13 level level NN cord-022526-j9kg00qf 1147 14 of of IN cord-022526-j9kg00qf 1147 15 energy energy NN cord-022526-j9kg00qf 1147 16 required require VBN cord-022526-j9kg00qf 1147 17 to to TO cord-022526-j9kg00qf 1147 18 fuel fuel VB cord-022526-j9kg00qf 1147 19 the the DT cord-022526-j9kg00qf 1147 20 Na Na NNP cord-022526-j9kg00qf 1148 1 + + CC cord-022526-j9kg00qf 1149 1 /K /K NNP cord-022526-j9kg00qf 1150 1 + + CC cord-022526-j9kg00qf 1151 1 -ATPase -atpase IN cord-022526-j9kg00qf 1151 2 that that DT cord-022526-j9kg00qf 1151 3 directly directly RB cord-022526-j9kg00qf 1151 4 or or CC cord-022526-j9kg00qf 1151 5 indirectly indirectly RB cord-022526-j9kg00qf 1151 6 regulates regulate VBZ cord-022526-j9kg00qf 1151 7 ion ion NN cord-022526-j9kg00qf 1151 8 and and CC cord-022526-j9kg00qf 1151 9 nutrient nutrient NN cord-022526-j9kg00qf 1151 10 flux flux NN cord-022526-j9kg00qf 1151 11 . . . cord-022526-j9kg00qf 1152 1 The the DT cord-022526-j9kg00qf 1152 2 first first JJ cord-022526-j9kg00qf 1152 3 biochemical biochemical JJ cord-022526-j9kg00qf 1152 4 event event NN cord-022526-j9kg00qf 1152 5 to to TO cord-022526-j9kg00qf 1152 6 occur occur VB cord-022526-j9kg00qf 1152 7 during during IN cord-022526-j9kg00qf 1152 8 hypoxia hypoxia NN cord-022526-j9kg00qf 1152 9 is be VBZ cord-022526-j9kg00qf 1152 10 a a DT cord-022526-j9kg00qf 1152 11 loss loss NN cord-022526-j9kg00qf 1152 12 of of IN cord-022526-j9kg00qf 1152 13 oxidative oxidative JJ cord-022526-j9kg00qf 1152 14 phosphorylation phosphorylation NN cord-022526-j9kg00qf 1152 15 . . . cord-022526-j9kg00qf 1153 1 The the DT cord-022526-j9kg00qf 1153 2 resulting result VBG cord-022526-j9kg00qf 1153 3 diminished diminish VBN cord-022526-j9kg00qf 1153 4 ATP ATP NNP cord-022526-j9kg00qf 1153 5 concentration concentration NN cord-022526-j9kg00qf 1153 6 causes cause VBZ cord-022526-j9kg00qf 1153 7 failure failure NN cord-022526-j9kg00qf 1153 8 of of IN cord-022526-j9kg00qf 1153 9 the the DT cord-022526-j9kg00qf 1153 10 energy energy NN cord-022526-j9kg00qf 1153 11 - - HYPH cord-022526-j9kg00qf 1153 12 dependent dependent JJ cord-022526-j9kg00qf 1153 13 Na Na NNP cord-022526-j9kg00qf 1153 14 + + CC cord-022526-j9kg00qf 1153 15 /K /K . cord-022526-j9kg00qf 1154 1 + + CC cord-022526-j9kg00qf 1155 1 -ATPase -atpase IN cord-022526-j9kg00qf 1155 2 resulting result VBG cord-022526-j9kg00qf 1155 3 in in IN cord-022526-j9kg00qf 1155 4 accumulation accumulation NN cord-022526-j9kg00qf 1155 5 of of IN cord-022526-j9kg00qf 1155 6 sodium sodium NN cord-022526-j9kg00qf 1155 7 , , , cord-022526-j9kg00qf 1155 8 and and CC cord-022526-j9kg00qf 1155 9 subsequently subsequently RB cord-022526-j9kg00qf 1155 10 intracellular intracellular JJ cord-022526-j9kg00qf 1155 11 water water NN cord-022526-j9kg00qf 1155 12 . . . cord-022526-j9kg00qf 1156 1 The the DT cord-022526-j9kg00qf 1156 2 pH ph NN cord-022526-j9kg00qf 1156 3 of of IN cord-022526-j9kg00qf 1156 4 the the DT cord-022526-j9kg00qf 1156 5 cytosol cytosol NN cord-022526-j9kg00qf 1156 6 drops drop VBZ cord-022526-j9kg00qf 1156 7 as as IN cord-022526-j9kg00qf 1156 8 lactic lactic JJ cord-022526-j9kg00qf 1156 9 acid acid NN cord-022526-j9kg00qf 1156 10 and and CC cord-022526-j9kg00qf 1156 11 inorganic inorganic JJ cord-022526-j9kg00qf 1156 12 phosphates phosphate NNS cord-022526-j9kg00qf 1156 13 accumulate accumulate VBP cord-022526-j9kg00qf 1156 14 from from IN cord-022526-j9kg00qf 1156 15 anaerobic anaerobic JJ cord-022526-j9kg00qf 1156 16 glycolysis glycolysis NN cord-022526-j9kg00qf 1156 17 . . . cord-022526-j9kg00qf 1157 1 The the DT cord-022526-j9kg00qf 1157 2 falling fall VBG cord-022526-j9kg00qf 1157 3 pH pH NNP cord-022526-j9kg00qf 1157 4 damages damage NNS cord-022526-j9kg00qf 1157 5 cell cell NN cord-022526-j9kg00qf 1157 6 membranes membrane NNS cord-022526-j9kg00qf 1157 7 , , , cord-022526-j9kg00qf 1157 8 including include VBG cord-022526-j9kg00qf 1157 9 lysosomal lysosomal JJ cord-022526-j9kg00qf 1157 10 membranes membrane NNS cord-022526-j9kg00qf 1157 11 , , , cord-022526-j9kg00qf 1157 12 resulting result VBG cord-022526-j9kg00qf 1157 13 in in IN cord-022526-j9kg00qf 1157 14 the the DT cord-022526-j9kg00qf 1157 15 release release NN cord-022526-j9kg00qf 1157 16 and and CC cord-022526-j9kg00qf 1157 17 activation activation NN cord-022526-j9kg00qf 1157 18 of of IN cord-022526-j9kg00qf 1157 19 lysosomal lysosomal JJ cord-022526-j9kg00qf 1157 20 enzymes enzyme NNS cord-022526-j9kg00qf 1157 21 into into IN cord-022526-j9kg00qf 1157 22 the the DT cord-022526-j9kg00qf 1157 23 cytosol cytosol NN cord-022526-j9kg00qf 1157 24 , , , cord-022526-j9kg00qf 1157 25 further further RB cord-022526-j9kg00qf 1157 26 damaging damaging JJ cord-022526-j9kg00qf 1157 27 cellular cellular JJ cord-022526-j9kg00qf 1157 28 membranes membrane NNS cord-022526-j9kg00qf 1157 29 . . . cord-022526-j9kg00qf 1158 1 Damage damage NN cord-022526-j9kg00qf 1158 2 to to IN cord-022526-j9kg00qf 1158 3 the the DT cord-022526-j9kg00qf 1158 4 cell cell NN cord-022526-j9kg00qf 1158 5 membrane membrane NN cord-022526-j9kg00qf 1158 6 allows allow VBZ cord-022526-j9kg00qf 1158 7 the the DT cord-022526-j9kg00qf 1158 8 accumulation accumulation NN cord-022526-j9kg00qf 1158 9 of of IN cord-022526-j9kg00qf 1158 10 high high JJ cord-022526-j9kg00qf 1158 11 concentrations concentration NNS cord-022526-j9kg00qf 1158 12 of of IN cord-022526-j9kg00qf 1158 13 calcium calcium NN cord-022526-j9kg00qf 1158 14 in in IN cord-022526-j9kg00qf 1158 15 the the DT cord-022526-j9kg00qf 1158 16 cytosol cytosol NN cord-022526-j9kg00qf 1158 17 , , , cord-022526-j9kg00qf 1158 18 which which WDT cord-022526-j9kg00qf 1158 19 activates activate VBZ cord-022526-j9kg00qf 1158 20 calciumdependent calciumdependent NN cord-022526-j9kg00qf 1158 21 degradative degradative NNS cord-022526-j9kg00qf 1158 22 enzymes enzyme NNS cord-022526-j9kg00qf 1158 23 . . . cord-022526-j9kg00qf 1159 1 63 63 CD cord-022526-j9kg00qf 1160 1 These these DT cord-022526-j9kg00qf 1160 2 events event NNS cord-022526-j9kg00qf 1160 3 result result VBP cord-022526-j9kg00qf 1160 4 in in IN cord-022526-j9kg00qf 1160 5 cytoplasmic cytoplasmic JJ cord-022526-j9kg00qf 1160 6 blebbing blebbing NN cord-022526-j9kg00qf 1160 7 of of IN cord-022526-j9kg00qf 1160 8 the the DT cord-022526-j9kg00qf 1160 9 basal basal NN cord-022526-j9kg00qf 1160 10 membrane membrane NN cord-022526-j9kg00qf 1160 11 with with IN cord-022526-j9kg00qf 1160 12 subsequent subsequent JJ cord-022526-j9kg00qf 1160 13 detachment detachment NN cord-022526-j9kg00qf 1160 14 of of IN cord-022526-j9kg00qf 1160 15 cells cell NNS cord-022526-j9kg00qf 1160 16 from from IN cord-022526-j9kg00qf 1160 17 the the DT cord-022526-j9kg00qf 1160 18 underlying underlying JJ cord-022526-j9kg00qf 1160 19 basement basement NN cord-022526-j9kg00qf 1160 20 membrane membrane NN cord-022526-j9kg00qf 1160 21 . . . cord-022526-j9kg00qf 1161 1 Recent recent JJ cord-022526-j9kg00qf 1161 2 studies study NNS cord-022526-j9kg00qf 1161 3 on on IN cord-022526-j9kg00qf 1161 4 epithelial epithelial JJ cord-022526-j9kg00qf 1161 5 injury injury NN cord-022526-j9kg00qf 1161 6 during during IN cord-022526-j9kg00qf 1161 7 ischemia ischemia NN cord-022526-j9kg00qf 1161 8 suggest suggest VBP cord-022526-j9kg00qf 1161 9 that that IN cord-022526-j9kg00qf 1161 10 most most JJS cord-022526-j9kg00qf 1161 11 epithelial epithelial JJ cord-022526-j9kg00qf 1161 12 cells cell NNS cord-022526-j9kg00qf 1161 13 undergo undergo VBP cord-022526-j9kg00qf 1161 14 programmed program VBN cord-022526-j9kg00qf 1161 15 cell cell NN cord-022526-j9kg00qf 1161 16 death death NN cord-022526-j9kg00qf 1161 17 ( ( -LRB- cord-022526-j9kg00qf 1161 18 apoptosis apoptosis NN cord-022526-j9kg00qf 1161 19 ) ) -RRB- cord-022526-j9kg00qf 1161 20 during during IN cord-022526-j9kg00qf 1161 21 ischemia ischemia NN cord-022526-j9kg00qf 1161 22 and and CC cord-022526-j9kg00qf 1161 23 reperfusion reperfusion NN cord-022526-j9kg00qf 1161 24 rather rather RB cord-022526-j9kg00qf 1161 25 than than IN cord-022526-j9kg00qf 1161 26 necrosis necrosis NN cord-022526-j9kg00qf 1161 27 , , , cord-022526-j9kg00qf 1161 28 allowing allow VBG cord-022526-j9kg00qf 1161 29 retention retention NN cord-022526-j9kg00qf 1161 30 of of IN cord-022526-j9kg00qf 1161 31 reusable reusable JJ cord-022526-j9kg00qf 1161 32 components component NNS cord-022526-j9kg00qf 1161 33 of of IN cord-022526-j9kg00qf 1161 34 irreversibly irreversibly RB cord-022526-j9kg00qf 1161 35 injured injure VBN cord-022526-j9kg00qf 1161 36 cells cell NNS cord-022526-j9kg00qf 1161 37 . . . cord-022526-j9kg00qf 1162 1 64 64 CD cord-022526-j9kg00qf 1163 1 In in IN cord-022526-j9kg00qf 1163 2 one one CD cord-022526-j9kg00qf 1163 3 study study NN cord-022526-j9kg00qf 1163 4 , , , cord-022526-j9kg00qf 1163 5 80 80 CD cord-022526-j9kg00qf 1163 6 % % NN cord-022526-j9kg00qf 1163 7 of of IN cord-022526-j9kg00qf 1163 8 detached detached JJ cord-022526-j9kg00qf 1163 9 epithelium epithelium NN cord-022526-j9kg00qf 1163 10 during during IN cord-022526-j9kg00qf 1163 11 small small JJ cord-022526-j9kg00qf 1163 12 intestinal intestinal JJ cord-022526-j9kg00qf 1163 13 ischemia ischemia NN cord-022526-j9kg00qf 1163 14 and and CC cord-022526-j9kg00qf 1163 15 reperfusion reperfusion NN cord-022526-j9kg00qf 1163 16 underwent undergo VBD cord-022526-j9kg00qf 1163 17 apoptosis apoptosis NN cord-022526-j9kg00qf 1163 18 . . . cord-022526-j9kg00qf 1164 1 65 65 CD cord-022526-j9kg00qf 1165 1 Although although IN cord-022526-j9kg00qf 1165 2 the the DT cord-022526-j9kg00qf 1165 3 most most RBS cord-022526-j9kg00qf 1165 4 obvious obvious JJ cord-022526-j9kg00qf 1165 5 result result NN cord-022526-j9kg00qf 1165 6 of of IN cord-022526-j9kg00qf 1165 7 apoptosis apoptosis NN cord-022526-j9kg00qf 1165 8 is be VBZ cord-022526-j9kg00qf 1165 9 loss loss NN cord-022526-j9kg00qf 1165 10 of of IN cord-022526-j9kg00qf 1165 11 surface surface NN cord-022526-j9kg00qf 1165 12 epithelium epithelium NN cord-022526-j9kg00qf 1165 13 , , , cord-022526-j9kg00qf 1165 14 a a DT cord-022526-j9kg00qf 1165 15 number number NN cord-022526-j9kg00qf 1165 16 of of IN cord-022526-j9kg00qf 1165 17 cells cell NNS cord-022526-j9kg00qf 1165 18 on on IN cord-022526-j9kg00qf 1165 19 the the DT cord-022526-j9kg00qf 1165 20 lower low JJR cord-022526-j9kg00qf 1165 21 portion portion NN cord-022526-j9kg00qf 1165 22 of of IN cord-022526-j9kg00qf 1165 23 the the DT cord-022526-j9kg00qf 1165 24 villus villus NN cord-022526-j9kg00qf 1165 25 ( ( -LRB- cord-022526-j9kg00qf 1165 26 in in IN cord-022526-j9kg00qf 1165 27 the the DT cord-022526-j9kg00qf 1165 28 small small JJ cord-022526-j9kg00qf 1165 29 intestine intestine NN cord-022526-j9kg00qf 1165 30 ) ) -RRB- cord-022526-j9kg00qf 1165 31 and and CC cord-022526-j9kg00qf 1165 32 cells cell NNS cord-022526-j9kg00qf 1165 33 within within IN cord-022526-j9kg00qf 1165 34 the the DT cord-022526-j9kg00qf 1165 35 crypts crypt NNS cord-022526-j9kg00qf 1165 36 also also RB cord-022526-j9kg00qf 1165 37 may may MD cord-022526-j9kg00qf 1165 38 undergo undergo VB cord-022526-j9kg00qf 1165 39 apoptosis apoptosis NN cord-022526-j9kg00qf 1165 40 that that IN cord-022526-j9kg00qf 1165 41 only only RB cord-022526-j9kg00qf 1165 42 may may MD cord-022526-j9kg00qf 1165 43 become become VB cord-022526-j9kg00qf 1165 44 evident evident JJ cord-022526-j9kg00qf 1165 45 up up IN cord-022526-j9kg00qf 1165 46 to to TO cord-022526-j9kg00qf 1165 47 24 24 CD cord-022526-j9kg00qf 1165 48 hours hour NNS cord-022526-j9kg00qf 1165 49 following follow VBG cord-022526-j9kg00qf 1165 50 reperfusion reperfusion NN cord-022526-j9kg00qf 1165 51 of of IN cord-022526-j9kg00qf 1165 52 ischemic ischemic JJ cord-022526-j9kg00qf 1165 53 tissue tissue NN cord-022526-j9kg00qf 1165 54 . . . cord-022526-j9kg00qf 1166 1 66 66 CD cord-022526-j9kg00qf 1167 1 Morphologic morphologic JJ cord-022526-j9kg00qf 1167 2 changes change NNS cord-022526-j9kg00qf 1167 3 observed observe VBN cord-022526-j9kg00qf 1167 4 in in IN cord-022526-j9kg00qf 1167 5 ischemic ischemic JJ cord-022526-j9kg00qf 1167 6 - - HYPH cord-022526-j9kg00qf 1167 7 injured injure VBN cord-022526-j9kg00qf 1167 8 small small JJ cord-022526-j9kg00qf 1167 9 intestinal intestinal JJ cord-022526-j9kg00qf 1167 10 mucosa mucosa RB cord-022526-j9kg00qf 1167 11 follow follow VBP cord-022526-j9kg00qf 1167 12 a a DT cord-022526-j9kg00qf 1167 13 similar similar JJ cord-022526-j9kg00qf 1167 14 sequence sequence NN cord-022526-j9kg00qf 1167 15 regardless regardless RB cord-022526-j9kg00qf 1167 16 of of IN cord-022526-j9kg00qf 1167 17 whether whether IN cord-022526-j9kg00qf 1167 18 ischemia ischemia NN cord-022526-j9kg00qf 1167 19 alone alone RB cord-022526-j9kg00qf 1167 20 or or CC cord-022526-j9kg00qf 1167 21 ischemia ischemia NN cord-022526-j9kg00qf 1167 22 and and CC cord-022526-j9kg00qf 1167 23 reperfusion reperfusion NN cord-022526-j9kg00qf 1167 24 induce induce VBP cord-022526-j9kg00qf 1167 25 injury injury NN cord-022526-j9kg00qf 1167 26 ( ( -LRB- cord-022526-j9kg00qf 1167 27 Table table NN cord-022526-j9kg00qf 1167 28 13 13 CD cord-022526-j9kg00qf 1167 29 .5 .5 CD cord-022526-j9kg00qf 1167 30 - - SYM cord-022526-j9kg00qf 1167 31 1 1 CD cord-022526-j9kg00qf 1167 32 ) ) -RRB- cord-022526-j9kg00qf 1167 33 . . . cord-022526-j9kg00qf 1168 1 67 67 CD cord-022526-j9kg00qf 1169 1 Initially initially RB cord-022526-j9kg00qf 1169 2 , , , cord-022526-j9kg00qf 1169 3 epithelium epithelium NN cord-022526-j9kg00qf 1169 4 separates separate VBZ cord-022526-j9kg00qf 1169 5 from from IN cord-022526-j9kg00qf 1169 6 the the DT cord-022526-j9kg00qf 1169 7 underlying underlying JJ cord-022526-j9kg00qf 1169 8 basement basement NN cord-022526-j9kg00qf 1169 9 membrane membrane NN cord-022526-j9kg00qf 1169 10 , , , cord-022526-j9kg00qf 1169 11 forming form VBG cord-022526-j9kg00qf 1169 12 a a DT cord-022526-j9kg00qf 1169 13 fluid fluid NN cord-022526-j9kg00qf 1169 14 - - HYPH cord-022526-j9kg00qf 1169 15 filled fill VBN cord-022526-j9kg00qf 1169 16 space space NN cord-022526-j9kg00qf 1169 17 termed term VBN cord-022526-j9kg00qf 1169 18 Grüenhagen Grüenhagen NNP cord-022526-j9kg00qf 1169 19 's 's POS cord-022526-j9kg00qf 1169 20 space space NN cord-022526-j9kg00qf 1169 21 ( ( -LRB- cord-022526-j9kg00qf 1169 22 Figure figure NN cord-022526-j9kg00qf 1169 23 13 13 CD cord-022526-j9kg00qf 1169 24 .5 .5 CD cord-022526-j9kg00qf 1169 25 - - HYPH cord-022526-j9kg00qf 1169 26 1 1 CD cord-022526-j9kg00qf 1169 27 ) ) -RRB- cord-022526-j9kg00qf 1169 28 . . . cord-022526-j9kg00qf 1170 1 The the DT cord-022526-j9kg00qf 1170 2 mechanism mechanism NN cord-022526-j9kg00qf 1170 3 of of IN cord-022526-j9kg00qf 1170 4 fluid fluid JJ cord-022526-j9kg00qf 1170 5 accumulation accumulation NN cord-022526-j9kg00qf 1170 6 in in IN cord-022526-j9kg00qf 1170 7 this this DT cord-022526-j9kg00qf 1170 8 space space NN cord-022526-j9kg00qf 1170 9 is be VBZ cord-022526-j9kg00qf 1170 10 not not RB cord-022526-j9kg00qf 1170 11 understood understand VBN cord-022526-j9kg00qf 1170 12 entirely entirely RB cord-022526-j9kg00qf 1170 13 but but CC cord-022526-j9kg00qf 1170 14 may may MD cord-022526-j9kg00qf 1170 15 result result VB cord-022526-j9kg00qf 1170 16 from from IN cord-022526-j9kg00qf 1170 17 continued continued JJ cord-022526-j9kg00qf 1170 18 epithelial epithelial JJ cord-022526-j9kg00qf 1170 19 absorption absorption NN cord-022526-j9kg00qf 1170 20 of of IN cord-022526-j9kg00qf 1170 21 NaCl nacl NN cord-022526-j9kg00qf 1170 22 and and CC cord-022526-j9kg00qf 1170 23 water water NN cord-022526-j9kg00qf 1170 24 before before IN cord-022526-j9kg00qf 1170 25 it -PRON- PRP cord-022526-j9kg00qf 1170 26 has have VBZ cord-022526-j9kg00qf 1170 27 detached detach VBN cord-022526-j9kg00qf 1170 28 fully fully RB cord-022526-j9kg00qf 1170 29 from from IN cord-022526-j9kg00qf 1170 30 neighboring neighbor VBG cord-022526-j9kg00qf 1170 31 epithelial epithelial JJ cord-022526-j9kg00qf 1170 32 cells cell NNS cord-022526-j9kg00qf 1170 33 . . . cord-022526-j9kg00qf 1171 1 This this DT cord-022526-j9kg00qf 1171 2 fluid fluid JJ cord-022526-j9kg00qf 1171 3 accumulation accumulation NN cord-022526-j9kg00qf 1171 4 likely likely RB cord-022526-j9kg00qf 1171 5 exacerbates exacerbate VBZ cord-022526-j9kg00qf 1171 6 epithelial epithelial JJ cord-022526-j9kg00qf 1171 7 separation separation NN cord-022526-j9kg00qf 1171 8 from from IN cord-022526-j9kg00qf 1171 9 the the DT cord-022526-j9kg00qf 1171 10 basement basement NN cord-022526-j9kg00qf 1171 11 membrane membrane NN cord-022526-j9kg00qf 1171 12 . . . cord-022526-j9kg00qf 1172 1 Subsequently subsequently RB cord-022526-j9kg00qf 1172 2 , , , cord-022526-j9kg00qf 1172 3 epithelium epithelium NN cord-022526-j9kg00qf 1172 4 progressively progressively RB cord-022526-j9kg00qf 1172 5 sloughs slough VBZ cord-022526-j9kg00qf 1172 6 from from IN cord-022526-j9kg00qf 1172 7 the the DT cord-022526-j9kg00qf 1172 8 tip tip NN cord-022526-j9kg00qf 1172 9 of of IN cord-022526-j9kg00qf 1172 10 the the DT cord-022526-j9kg00qf 1172 11 villus villus NN cord-022526-j9kg00qf 1172 12 toward toward IN cord-022526-j9kg00qf 1172 13 the the DT cord-022526-j9kg00qf 1172 14 crypts crypt NNS cord-022526-j9kg00qf 1172 15 , , , cord-022526-j9kg00qf 1172 16 which which WDT cord-022526-j9kg00qf 1172 17 are be VBP cord-022526-j9kg00qf 1172 18 the the DT cord-022526-j9kg00qf 1172 19 last last JJ cord-022526-j9kg00qf 1172 20 component component NN cord-022526-j9kg00qf 1172 21 of of IN cord-022526-j9kg00qf 1172 22 the the DT cord-022526-j9kg00qf 1172 23 intestinal intestinal JJ cord-022526-j9kg00qf 1172 24 mucosa mucosa NN cord-022526-j9kg00qf 1172 25 to to TO cord-022526-j9kg00qf 1172 26 become become VB cord-022526-j9kg00qf 1172 27 injured injure VBN cord-022526-j9kg00qf 1172 28 . . . cord-022526-j9kg00qf 1173 1 [ [ -LRB- cord-022526-j9kg00qf 1173 2 68 68 CD cord-022526-j9kg00qf 1173 3 ] ] -RRB- cord-022526-j9kg00qf 1173 4 [ [ -LRB- cord-022526-j9kg00qf 1173 5 69 69 CD cord-022526-j9kg00qf 1173 6 ] ] -RRB- cord-022526-j9kg00qf 1173 7 [ [ -LRB- cord-022526-j9kg00qf 1173 8 70 70 CD cord-022526-j9kg00qf 1173 9 ] ] -RRB- cord-022526-j9kg00qf 1173 10 Injury injury NN cord-022526-j9kg00qf 1173 11 of of IN cord-022526-j9kg00qf 1173 12 crypts crypt NNS cord-022526-j9kg00qf 1173 13 likely likely RB cord-022526-j9kg00qf 1173 14 relates relate VBZ cord-022526-j9kg00qf 1173 15 to to IN cord-022526-j9kg00qf 1173 16 the the DT cord-022526-j9kg00qf 1173 17 vascular vascular JJ cord-022526-j9kg00qf 1173 18 architecture architecture NN cord-022526-j9kg00qf 1173 19 , , , cord-022526-j9kg00qf 1173 20 because because IN cord-022526-j9kg00qf 1173 21 crypts crypt NNS cord-022526-j9kg00qf 1173 22 receive receive VBP cord-022526-j9kg00qf 1173 23 a a DT cord-022526-j9kg00qf 1173 24 blood blood NN cord-022526-j9kg00qf 1173 25 supply supply NN cord-022526-j9kg00qf 1173 26 separate separate JJ cord-022526-j9kg00qf 1173 27 from from IN cord-022526-j9kg00qf 1173 28 the the DT cord-022526-j9kg00qf 1173 29 vasculature vasculature NN cord-022526-j9kg00qf 1173 30 involved involve VBN cord-022526-j9kg00qf 1173 31 in in IN cord-022526-j9kg00qf 1173 32 the the DT cord-022526-j9kg00qf 1173 33 villous villous NNP cord-022526-j9kg00qf 1173 34 countercurrent countercurrent NNP cord-022526-j9kg00qf 1173 35 exchange exchange NN cord-022526-j9kg00qf 1173 36 mechanism mechanism NN cord-022526-j9kg00qf 1173 37 . . . cord-022526-j9kg00qf 1174 1 The the DT cord-022526-j9kg00qf 1174 2 early early JJ cord-022526-j9kg00qf 1174 3 morphologic morphologic JJ cord-022526-j9kg00qf 1174 4 changes change NNS cord-022526-j9kg00qf 1174 5 observed observe VBN cord-022526-j9kg00qf 1174 6 in in IN cord-022526-j9kg00qf 1174 7 the the DT cord-022526-j9kg00qf 1174 8 equine equine JJ cord-022526-j9kg00qf 1174 9 large large JJ cord-022526-j9kg00qf 1174 10 colon colon NN cord-022526-j9kg00qf 1174 11 during during IN cord-022526-j9kg00qf 1174 12 ischemia ischemia NN cord-022526-j9kg00qf 1174 13 are be VBP cord-022526-j9kg00qf 1174 14 different different JJ cord-022526-j9kg00qf 1174 15 from from IN cord-022526-j9kg00qf 1174 16 those those DT cord-022526-j9kg00qf 1174 17 described describe VBN cord-022526-j9kg00qf 1174 18 in in IN cord-022526-j9kg00qf 1174 19 the the DT cord-022526-j9kg00qf 1174 20 equine equine JJ cord-022526-j9kg00qf 1174 21 small small JJ cord-022526-j9kg00qf 1174 22 intestine intestine NN cord-022526-j9kg00qf 1174 23 because because IN cord-022526-j9kg00qf 1174 24 of of IN cord-022526-j9kg00qf 1174 25 the the DT cord-022526-j9kg00qf 1174 26 lack lack NN cord-022526-j9kg00qf 1174 27 of of IN cord-022526-j9kg00qf 1174 28 intestinal intestinal JJ cord-022526-j9kg00qf 1174 29 villi villi NN cord-022526-j9kg00qf 1174 30 . . . cord-022526-j9kg00qf 1175 1 However however RB cord-022526-j9kg00qf 1175 2 , , , cord-022526-j9kg00qf 1175 3 as as IN cord-022526-j9kg00qf 1175 4 might may MD cord-022526-j9kg00qf 1175 5 be be VB cord-022526-j9kg00qf 1175 6 expected expect VBN cord-022526-j9kg00qf 1175 7 , , , cord-022526-j9kg00qf 1175 8 the the DT cord-022526-j9kg00qf 1175 9 more more RBR cord-022526-j9kg00qf 1175 10 superficially superficially RB cord-022526-j9kg00qf 1175 11 located locate VBN cord-022526-j9kg00qf 1175 12 surface surface NN cord-022526-j9kg00qf 1175 13 cells cell NNS cord-022526-j9kg00qf 1175 14 are be VBP cord-022526-j9kg00qf 1175 15 sloughed slough VBN cord-022526-j9kg00qf 1175 16 before before IN cord-022526-j9kg00qf 1175 17 those those DT cord-022526-j9kg00qf 1175 18 in in IN cord-022526-j9kg00qf 1175 19 crypts crypt NNS cord-022526-j9kg00qf 1175 20 . . . cord-022526-j9kg00qf 1176 1 62 62 CD cord-022526-j9kg00qf 1176 2 , , , cord-022526-j9kg00qf 1176 3 71 71 CD cord-022526-j9kg00qf 1177 1 The the DT cord-022526-j9kg00qf 1177 2 orderly orderly JJ cord-022526-j9kg00qf 1177 3 progression progression NN cord-022526-j9kg00qf 1177 4 of of IN cord-022526-j9kg00qf 1177 5 tissue tissue NN cord-022526-j9kg00qf 1177 6 injury injury NN cord-022526-j9kg00qf 1177 7 has have VBZ cord-022526-j9kg00qf 1177 8 been be VBN cord-022526-j9kg00qf 1177 9 used use VBN cord-022526-j9kg00qf 1177 10 by by IN cord-022526-j9kg00qf 1177 11 one one CD cord-022526-j9kg00qf 1177 12 group group NN cord-022526-j9kg00qf 1177 13 of of IN cord-022526-j9kg00qf 1177 14 investigators investigator NNS cord-022526-j9kg00qf 1177 15 to to TO cord-022526-j9kg00qf 1177 16 predict predict VB cord-022526-j9kg00qf 1177 17 accurately accurately RB cord-022526-j9kg00qf 1177 18 the the DT cord-022526-j9kg00qf 1177 19 survival survival NN cord-022526-j9kg00qf 1177 20 of of IN cord-022526-j9kg00qf 1177 21 horses horse NNS cord-022526-j9kg00qf 1177 22 with with IN cord-022526-j9kg00qf 1177 23 large large JJ cord-022526-j9kg00qf 1177 24 colon colon NN cord-022526-j9kg00qf 1177 25 volvulus volvulus NN cord-022526-j9kg00qf 1177 26 . . . cord-022526-j9kg00qf 1178 1 The the DT cord-022526-j9kg00qf 1178 2 researchers researcher NNS cord-022526-j9kg00qf 1178 3 took take VBD cord-022526-j9kg00qf 1178 4 biopsies biopsy NNS cord-022526-j9kg00qf 1178 5 from from IN cord-022526-j9kg00qf 1178 6 the the DT cord-022526-j9kg00qf 1178 7 pelvic pelvic JJ cord-022526-j9kg00qf 1178 8 flexure flexure NN cord-022526-j9kg00qf 1178 9 , , , cord-022526-j9kg00qf 1178 10 which which WDT cord-022526-j9kg00qf 1178 11 has have VBZ cord-022526-j9kg00qf 1178 12 been be VBN cord-022526-j9kg00qf 1178 13 shown show VBN cord-022526-j9kg00qf 1178 14 previously previously RB cord-022526-j9kg00qf 1178 15 to to TO cord-022526-j9kg00qf 1178 16 reflect reflect VB cord-022526-j9kg00qf 1178 17 mucosal mucosal JJ cord-022526-j9kg00qf 1178 18 changes change NNS cord-022526-j9kg00qf 1178 19 along along IN cord-022526-j9kg00qf 1178 20 the the DT cord-022526-j9kg00qf 1178 21 length length NN cord-022526-j9kg00qf 1178 22 of of IN cord-022526-j9kg00qf 1178 23 the the DT cord-022526-j9kg00qf 1178 24 colon colon NN cord-022526-j9kg00qf 1178 25 accurately accurately RB cord-022526-j9kg00qf 1178 26 , , , cord-022526-j9kg00qf 1178 27 72 72 CD cord-022526-j9kg00qf 1178 28 and and CC cord-022526-j9kg00qf 1178 29 examined examine VBD cord-022526-j9kg00qf 1178 30 them -PRON- PRP cord-022526-j9kg00qf 1178 31 histologically histologically RB cord-022526-j9kg00qf 1178 32 for for IN cord-022526-j9kg00qf 1178 33 the the DT cord-022526-j9kg00qf 1178 34 width width NN cord-022526-j9kg00qf 1178 35 of of IN cord-022526-j9kg00qf 1178 36 the the DT cord-022526-j9kg00qf 1178 37 crypts crypt NNS cord-022526-j9kg00qf 1178 38 and and CC cord-022526-j9kg00qf 1178 39 intercrypt intercrypt JJ cord-022526-j9kg00qf 1178 40 interstitial interstitial JJ cord-022526-j9kg00qf 1178 41 space space NN cord-022526-j9kg00qf 1178 42 . . . cord-022526-j9kg00qf 1179 1 They -PRON- PRP cord-022526-j9kg00qf 1179 2 expressed express VBD cord-022526-j9kg00qf 1179 3 the the DT cord-022526-j9kg00qf 1179 4 latter latter JJ cord-022526-j9kg00qf 1179 5 measurements measurement NNS cord-022526-j9kg00qf 1179 6 as as IN cord-022526-j9kg00qf 1179 7 a a DT cord-022526-j9kg00qf 1179 8 ratio ratio NN cord-022526-j9kg00qf 1179 9 of of IN cord-022526-j9kg00qf 1179 10 interstitium interstitium NN cord-022526-j9kg00qf 1179 11 to to IN cord-022526-j9kg00qf 1179 12 crypt crypt NN cord-022526-j9kg00qf 1179 13 width width NNP cord-022526-j9kg00qf 1179 14 ( ( -LRB- cord-022526-j9kg00qf 1179 15 I i NN cord-022526-j9kg00qf 1179 16 : : : cord-022526-j9kg00qf 1179 17 C C NNP cord-022526-j9kg00qf 1179 18 ) ) -RRB- cord-022526-j9kg00qf 1179 19 and and CC cord-022526-j9kg00qf 1179 20 defined define VBD cord-022526-j9kg00qf 1179 21 nonviable nonviable JJ cord-022526-j9kg00qf 1179 22 colon colon NN cord-022526-j9kg00qf 1179 23 as as IN cord-022526-j9kg00qf 1179 24 that that DT cord-022526-j9kg00qf 1179 25 which which WDT cord-022526-j9kg00qf 1179 26 has have VBZ cord-022526-j9kg00qf 1179 27 greater great JJR cord-022526-j9kg00qf 1179 28 than than IN cord-022526-j9kg00qf 1179 29 60 60 CD cord-022526-j9kg00qf 1179 30 % % NN cord-022526-j9kg00qf 1179 31 loss loss NN cord-022526-j9kg00qf 1179 32 of of IN cord-022526-j9kg00qf 1179 33 crypt crypt NN cord-022526-j9kg00qf 1179 34 and and CC cord-022526-j9kg00qf 1179 35 an an DT cord-022526-j9kg00qf 1179 36 I i NN cord-022526-j9kg00qf 1179 37 : : : cord-022526-j9kg00qf 1179 38 C c NN cord-022526-j9kg00qf 1179 39 ratio ratio NN cord-022526-j9kg00qf 1179 40 greater great JJR cord-022526-j9kg00qf 1179 41 than than IN cord-022526-j9kg00qf 1179 42 3 3 CD cord-022526-j9kg00qf 1179 43 . . . cord-022526-j9kg00qf 1180 1 Using use VBG cord-022526-j9kg00qf 1180 2 this this DT cord-022526-j9kg00qf 1180 3 methodology methodology NN cord-022526-j9kg00qf 1180 4 , , , cord-022526-j9kg00qf 1180 5 researchers researcher NNS cord-022526-j9kg00qf 1180 6 correctly correctly RB cord-022526-j9kg00qf 1180 7 predicted predict VBD cord-022526-j9kg00qf 1180 8 survival survival NN cord-022526-j9kg00qf 1180 9 in in IN cord-022526-j9kg00qf 1180 10 94 94 CD cord-022526-j9kg00qf 1180 11 % % NN cord-022526-j9kg00qf 1180 12 of of IN cord-022526-j9kg00qf 1180 13 horses horse NNS cord-022526-j9kg00qf 1180 14 . . . cord-022526-j9kg00qf 1181 1 73 73 CD cord-022526-j9kg00qf 1181 2 _SP cord-022526-j9kg00qf 1182 1 Because because IN cord-022526-j9kg00qf 1182 2 of of IN cord-022526-j9kg00qf 1182 3 the the DT cord-022526-j9kg00qf 1182 4 dramatic dramatic JJ cord-022526-j9kg00qf 1182 5 decline decline NN cord-022526-j9kg00qf 1182 6 in in IN cord-022526-j9kg00qf 1182 7 Strongylus Strongylus NNP cord-022526-j9kg00qf 1182 8 vulgarisinduced vulgarisinduced JJ cord-022526-j9kg00qf 1182 9 colic colic NN cord-022526-j9kg00qf 1182 10 , , , cord-022526-j9kg00qf 1182 11 which which WDT cord-022526-j9kg00qf 1182 12 was be VBD cord-022526-j9kg00qf 1182 13 associated associate VBN cord-022526-j9kg00qf 1182 14 frequently frequently RB cord-022526-j9kg00qf 1182 15 with with IN cord-022526-j9kg00qf 1182 16 infarction infarction NN cord-022526-j9kg00qf 1182 17 of of IN cord-022526-j9kg00qf 1182 18 intestinal intestinal JJ cord-022526-j9kg00qf 1182 19 arterial arterial JJ cord-022526-j9kg00qf 1182 20 blood blood NN cord-022526-j9kg00qf 1182 21 supply supply NN cord-022526-j9kg00qf 1182 22 , , , cord-022526-j9kg00qf 1182 23 74 74 CD cord-022526-j9kg00qf 1182 24 most most JJS cord-022526-j9kg00qf 1182 25 ischemic ischemic JJ cord-022526-j9kg00qf 1182 26 lesions lesion NNS cord-022526-j9kg00qf 1182 27 are be VBP cord-022526-j9kg00qf 1182 28 associated associate VBN cord-022526-j9kg00qf 1182 29 with with IN cord-022526-j9kg00qf 1182 30 strangulating strangulating JJ cord-022526-j9kg00qf 1182 31 obstruction obstruction NN cord-022526-j9kg00qf 1182 32 . . . cord-022526-j9kg00qf 1183 1 Therefore therefore RB cord-022526-j9kg00qf 1183 2 considering consider VBG cord-022526-j9kg00qf 1183 3 mechanisms mechanism NNS cord-022526-j9kg00qf 1183 4 of of IN cord-022526-j9kg00qf 1183 5 ischemic ischemic JJ cord-022526-j9kg00qf 1183 6 injury injury NN cord-022526-j9kg00qf 1183 7 in in IN cord-022526-j9kg00qf 1183 8 horses horse NNS cord-022526-j9kg00qf 1183 9 with with IN cord-022526-j9kg00qf 1183 10 naturally naturally RB cord-022526-j9kg00qf 1183 11 occurring occur VBG cord-022526-j9kg00qf 1183 12 strangulating strangulate VBG cord-022526-j9kg00qf 1183 13 lesions lesion NNS cord-022526-j9kg00qf 1183 14 is be VBZ cord-022526-j9kg00qf 1183 15 important important JJ cord-022526-j9kg00qf 1183 16 . . . cord-022526-j9kg00qf 1184 1 The the DT cord-022526-j9kg00qf 1184 2 majority majority NN cord-022526-j9kg00qf 1184 3 of of IN cord-022526-j9kg00qf 1184 4 experimental experimental JJ cord-022526-j9kg00qf 1184 5 work work NN cord-022526-j9kg00qf 1184 6 has have VBZ cord-022526-j9kg00qf 1184 7 assessed assess VBN cord-022526-j9kg00qf 1184 8 complete complete JJ cord-022526-j9kg00qf 1184 9 ischemia ischemia NN cord-022526-j9kg00qf 1184 10 ( ( -LRB- cord-022526-j9kg00qf 1184 11 complete complete JJ cord-022526-j9kg00qf 1184 12 occlusion occlusion NN cord-022526-j9kg00qf 1184 13 of of IN cord-022526-j9kg00qf 1184 14 the the DT cord-022526-j9kg00qf 1184 15 arterial arterial JJ cord-022526-j9kg00qf 1184 16 blood blood NN cord-022526-j9kg00qf 1184 17 supply supply NN cord-022526-j9kg00qf 1184 18 ) ) -RRB- cord-022526-j9kg00qf 1185 1 62 62 CD cord-022526-j9kg00qf 1185 2 or or CC cord-022526-j9kg00qf 1185 3 low low JJ cord-022526-j9kg00qf 1185 4 - - HYPH cord-022526-j9kg00qf 1185 5 flow flow NN cord-022526-j9kg00qf 1185 6 ischemia ischemia NN cord-022526-j9kg00qf 1185 7 ( ( -LRB- cord-022526-j9kg00qf 1185 8 during during IN cord-022526-j9kg00qf 1185 9 which which WDT cord-022526-j9kg00qf 1185 10 arterial arterial JJ cord-022526-j9kg00qf 1185 11 blood blood NN cord-022526-j9kg00qf 1185 12 flow flow NN cord-022526-j9kg00qf 1185 13 is be VBZ cord-022526-j9kg00qf 1185 14 reduced reduce VBN cord-022526-j9kg00qf 1185 15 ) ) -RRB- cord-022526-j9kg00qf 1185 16 . . . cord-022526-j9kg00qf 1186 1 75 75 CD cord-022526-j9kg00qf 1186 2 , , , cord-022526-j9kg00qf 1186 3 76 76 CD cord-022526-j9kg00qf 1186 4 However however RB cord-022526-j9kg00qf 1186 5 , , , cord-022526-j9kg00qf 1186 6 during during IN cord-022526-j9kg00qf 1186 7 intestinal intestinal JJ cord-022526-j9kg00qf 1186 8 strangulation strangulation NN cord-022526-j9kg00qf 1186 9 , , , cord-022526-j9kg00qf 1186 10 a a DT cord-022526-j9kg00qf 1186 11 disparity disparity NN cord-022526-j9kg00qf 1186 12 between between IN cord-022526-j9kg00qf 1186 13 the the DT cord-022526-j9kg00qf 1186 14 degree degree NN cord-022526-j9kg00qf 1186 15 of of IN cord-022526-j9kg00qf 1186 16 occlusion occlusion NN cord-022526-j9kg00qf 1186 17 of of IN cord-022526-j9kg00qf 1186 18 the the DT cord-022526-j9kg00qf 1186 19 veins vein NNS cord-022526-j9kg00qf 1186 20 and and CC cord-022526-j9kg00qf 1186 21 arteries artery NNS cord-022526-j9kg00qf 1186 22 occurs occur VBZ cord-022526-j9kg00qf 1186 23 whereby whereby WRB cord-022526-j9kg00qf 1186 24 veins vein NNS cord-022526-j9kg00qf 1186 25 are be VBP cord-022526-j9kg00qf 1186 26 occluded occlude VBN cord-022526-j9kg00qf 1186 27 before before IN cord-022526-j9kg00qf 1186 28 arteries artery NNS cord-022526-j9kg00qf 1186 29 because because IN cord-022526-j9kg00qf 1186 30 of of IN cord-022526-j9kg00qf 1186 31 differences difference NNS cord-022526-j9kg00qf 1186 32 in in IN cord-022526-j9kg00qf 1186 33 compliance compliance NN cord-022526-j9kg00qf 1186 34 of of IN cord-022526-j9kg00qf 1186 35 vascular vascular JJ cord-022526-j9kg00qf 1186 36 walls wall NNS cord-022526-j9kg00qf 1186 37 . . . cord-022526-j9kg00qf 1187 1 Thus thus RB cord-022526-j9kg00qf 1187 2 strangulating strangulating JJ cord-022526-j9kg00qf 1187 3 lesions lesion NNS cord-022526-j9kg00qf 1187 4 are be VBP cord-022526-j9kg00qf 1187 5 typically typically RB cord-022526-j9kg00qf 1187 6 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 1187 7 ( ( -LRB- cord-022526-j9kg00qf 1187 8 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 1187 9 strangulating strangulating JJ cord-022526-j9kg00qf 1187 10 obstruction obstruction NN cord-022526-j9kg00qf 1187 11 ) ) -RRB- cord-022526-j9kg00qf 1187 12 as as IN cord-022526-j9kg00qf 1187 13 the the DT cord-022526-j9kg00qf 1187 14 arteries artery NNS cord-022526-j9kg00qf 1187 15 continue continue VBP cord-022526-j9kg00qf 1187 16 to to TO cord-022526-j9kg00qf 1187 17 supply supply VB cord-022526-j9kg00qf 1187 18 blood blood NN cord-022526-j9kg00qf 1187 19 to to IN cord-022526-j9kg00qf 1187 20 tissues tissue NNS cord-022526-j9kg00qf 1187 21 that that WDT cord-022526-j9kg00qf 1187 22 have have VBP cord-022526-j9kg00qf 1187 23 little little JJ cord-022526-j9kg00qf 1187 24 or or CC cord-022526-j9kg00qf 1187 25 no no DT cord-022526-j9kg00qf 1187 26 venous venous JJ cord-022526-j9kg00qf 1187 27 drainage drainage NN cord-022526-j9kg00qf 1187 28 . . . cord-022526-j9kg00qf 1188 1 The the DT cord-022526-j9kg00qf 1188 2 result result NN cord-022526-j9kg00qf 1188 3 is be VBZ cord-022526-j9kg00qf 1188 4 ischemic ischemic JJ cord-022526-j9kg00qf 1188 5 injury injury NN cord-022526-j9kg00qf 1188 6 , , , cord-022526-j9kg00qf 1188 7 as as IN cord-022526-j9kg00qf 1188 8 previously previously RB cord-022526-j9kg00qf 1188 9 outlined outline VBN cord-022526-j9kg00qf 1188 10 , , , cord-022526-j9kg00qf 1188 11 but but CC cord-022526-j9kg00qf 1188 12 also also RB cord-022526-j9kg00qf 1188 13 a a DT cord-022526-j9kg00qf 1188 14 tremendous tremendous JJ cord-022526-j9kg00qf 1188 15 congestion congestion NN cord-022526-j9kg00qf 1188 16 of of IN cord-022526-j9kg00qf 1188 17 the the DT cord-022526-j9kg00qf 1188 18 tissues tissue NNS cord-022526-j9kg00qf 1188 19 . . . cord-022526-j9kg00qf 1189 1 Such such JJ cord-022526-j9kg00qf 1189 2 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 1189 3 congestion congestion NN cord-022526-j9kg00qf 1189 4 has have VBZ cord-022526-j9kg00qf 1189 5 two two CD cord-022526-j9kg00qf 1189 6 opposing oppose VBG cord-022526-j9kg00qf 1189 7 effects effect NNS cord-022526-j9kg00qf 1189 8 : : : cord-022526-j9kg00qf 1189 9 it -PRON- PRP cord-022526-j9kg00qf 1189 10 disrupts disrupt VBZ cord-022526-j9kg00qf 1189 11 tissue tissue NN cord-022526-j9kg00qf 1189 12 architecture architecture NN cord-022526-j9kg00qf 1189 13 , , , cord-022526-j9kg00qf 1189 14 including include VBG cord-022526-j9kg00qf 1189 15 the the DT cord-022526-j9kg00qf 1189 16 mucosa mucosa NN cord-022526-j9kg00qf 1189 17 and and CC cord-022526-j9kg00qf 1189 18 its -PRON- PRP$ cord-022526-j9kg00qf 1189 19 epithelium epithelium NN cord-022526-j9kg00qf 1189 20 , , , cord-022526-j9kg00qf 1189 21 and and CC cord-022526-j9kg00qf 1189 22 continues continue VBZ cord-022526-j9kg00qf 1189 23 to to TO cord-022526-j9kg00qf 1189 24 provide provide VB cord-022526-j9kg00qf 1189 25 oxygenated oxygenated JJ cord-022526-j9kg00qf 1189 26 blood blood NN cord-022526-j9kg00qf 1189 27 to to IN cord-022526-j9kg00qf 1189 28 the the DT cord-022526-j9kg00qf 1189 29 tissues tissue NNS cord-022526-j9kg00qf 1189 30 during during IN cord-022526-j9kg00qf 1189 31 much much JJ cord-022526-j9kg00qf 1189 32 of of IN cord-022526-j9kg00qf 1189 33 the the DT cord-022526-j9kg00qf 1189 34 ischemic ischemic JJ cord-022526-j9kg00qf 1189 35 episode episode NN cord-022526-j9kg00qf 1189 36 . . . cord-022526-j9kg00qf 1190 1 In in IN cord-022526-j9kg00qf 1190 2 contrast contrast NN cord-022526-j9kg00qf 1190 3 , , , cord-022526-j9kg00qf 1190 4 when when WRB cord-022526-j9kg00qf 1190 5 strangulation strangulation NN cord-022526-j9kg00qf 1190 6 results result VBZ cord-022526-j9kg00qf 1190 7 in in IN cord-022526-j9kg00qf 1190 8 sudden sudden JJ cord-022526-j9kg00qf 1190 9 cessation cessation NN cord-022526-j9kg00qf 1190 10 of of IN cord-022526-j9kg00qf 1190 11 arterial arterial JJ cord-022526-j9kg00qf 1190 12 blood blood NN cord-022526-j9kg00qf 1190 13 flow flow NN cord-022526-j9kg00qf 1190 14 ( ( -LRB- cord-022526-j9kg00qf 1190 15 ischemic ischemic JJ cord-022526-j9kg00qf 1190 16 strangulating strangulating JJ cord-022526-j9kg00qf 1190 17 obstruction obstruction NN cord-022526-j9kg00qf 1190 18 ) ) -RRB- cord-022526-j9kg00qf 1190 19 , , , cord-022526-j9kg00qf 1190 20 tissues tissue NNS cord-022526-j9kg00qf 1190 21 appear appear VBP cord-022526-j9kg00qf 1190 22 pale pale JJ cord-022526-j9kg00qf 1190 23 , , , cord-022526-j9kg00qf 1190 24 and and CC cord-022526-j9kg00qf 1190 25 the the DT cord-022526-j9kg00qf 1190 26 mucosa mucosa NN cord-022526-j9kg00qf 1190 27 rapidly rapidly RB cord-022526-j9kg00qf 1190 28 degenerates degenerate VBZ cord-022526-j9kg00qf 1190 29 because because IN cord-022526-j9kg00qf 1190 30 of of IN cord-022526-j9kg00qf 1190 31 a a DT cord-022526-j9kg00qf 1190 32 complete complete JJ cord-022526-j9kg00qf 1190 33 lack lack NN cord-022526-j9kg00qf 1190 34 of of IN cord-022526-j9kg00qf 1190 35 oxygenated oxygenated JJ cord-022526-j9kg00qf 1190 36 blood blood NN cord-022526-j9kg00qf 1190 37 . . . cord-022526-j9kg00qf 1191 1 70 70 CD cord-022526-j9kg00qf 1192 1 because because IN cord-022526-j9kg00qf 1192 2 intestine intestine NN cord-022526-j9kg00qf 1192 3 that that WDT cord-022526-j9kg00qf 1192 4 may may MD cord-022526-j9kg00qf 1192 5 look look VB cord-022526-j9kg00qf 1192 6 nonviable nonviable JJ cord-022526-j9kg00qf 1192 7 ( ( -LRB- cord-022526-j9kg00qf 1192 8 dark dark JJ cord-022526-j9kg00qf 1192 9 red red JJ cord-022526-j9kg00qf 1192 10 ) ) -RRB- cord-022526-j9kg00qf 1192 11 may may MD cord-022526-j9kg00qf 1192 12 in in IN cord-022526-j9kg00qf 1192 13 fact fact NN cord-022526-j9kg00qf 1192 14 have have VB cord-022526-j9kg00qf 1192 15 less less RBR cord-022526-j9kg00qf 1192 16 mucosal mucosal JJ cord-022526-j9kg00qf 1192 17 injury injury NN cord-022526-j9kg00qf 1192 18 than than IN cord-022526-j9kg00qf 1192 19 that that DT cord-022526-j9kg00qf 1192 20 of of IN cord-022526-j9kg00qf 1192 21 ischemic ischemic JJ cord-022526-j9kg00qf 1192 22 strangulated strangulated JJ cord-022526-j9kg00qf 1192 23 intestine intestine NN cord-022526-j9kg00qf 1192 24 . . . cord-022526-j9kg00qf 1193 1 77 77 CD cord-022526-j9kg00qf 1194 1 An an DT cord-022526-j9kg00qf 1194 2 additional additional JJ cord-022526-j9kg00qf 1194 3 consideration consideration NN cord-022526-j9kg00qf 1194 4 in in IN cord-022526-j9kg00qf 1194 5 clinical clinical JJ cord-022526-j9kg00qf 1194 6 strangulating strangulating JJ cord-022526-j9kg00qf 1194 7 obstruction obstruction NN cord-022526-j9kg00qf 1194 8 is be VBZ cord-022526-j9kg00qf 1194 9 the the DT cord-022526-j9kg00qf 1194 10 degree degree NN cord-022526-j9kg00qf 1194 11 of of IN cord-022526-j9kg00qf 1194 12 ischemia ischemia NN cord-022526-j9kg00qf 1194 13 that that IN cord-022526-j9kg00qf 1194 14 intestinal intestinal JJ cord-022526-j9kg00qf 1194 15 distention distention NN cord-022526-j9kg00qf 1194 16 may may MD cord-022526-j9kg00qf 1194 17 induce induce VB cord-022526-j9kg00qf 1194 18 . . . cord-022526-j9kg00qf 1195 1 For for IN cord-022526-j9kg00qf 1195 2 example example NN cord-022526-j9kg00qf 1195 3 , , , cord-022526-j9kg00qf 1195 4 experimental experimental JJ cord-022526-j9kg00qf 1195 5 distention distention NN cord-022526-j9kg00qf 1195 6 ( ( -LRB- cord-022526-j9kg00qf 1195 7 18 18 CD cord-022526-j9kg00qf 1195 8 cm cm NNS cord-022526-j9kg00qf 1195 9 of of IN cord-022526-j9kg00qf 1195 10 H h NN cord-022526-j9kg00qf 1195 11 2 2 CD cord-022526-j9kg00qf 1195 12 O o NN cord-022526-j9kg00qf 1195 13 for for IN cord-022526-j9kg00qf 1195 14 2 2 CD cord-022526-j9kg00qf 1195 15 hours hour NNS cord-022526-j9kg00qf 1195 16 ) ) -RRB- cord-022526-j9kg00qf 1195 17 and and CC cord-022526-j9kg00qf 1195 18 decompression decompression NN cord-022526-j9kg00qf 1195 19 ( ( -LRB- cord-022526-j9kg00qf 1195 20 2 2 CD cord-022526-j9kg00qf 1195 21 hours hour NNS cord-022526-j9kg00qf 1195 22 ) ) -RRB- cord-022526-j9kg00qf 1195 23 of of IN cord-022526-j9kg00qf 1195 24 jejunum jejunum NNS cord-022526-j9kg00qf 1195 25 resulted result VBD cord-022526-j9kg00qf 1195 26 in in IN cord-022526-j9kg00qf 1195 27 a a DT cord-022526-j9kg00qf 1195 28 significant significant JJ cord-022526-j9kg00qf 1195 29 increase increase NN cord-022526-j9kg00qf 1195 30 in in IN cord-022526-j9kg00qf 1195 31 microvascular microvascular JJ cord-022526-j9kg00qf 1195 32 permeability permeability NN cord-022526-j9kg00qf 1195 33 and and CC cord-022526-j9kg00qf 1195 34 a a DT cord-022526-j9kg00qf 1195 35 significant significant JJ cord-022526-j9kg00qf 1195 36 decrease decrease NN cord-022526-j9kg00qf 1195 37 in in IN cord-022526-j9kg00qf 1195 38 tissue tissue NN cord-022526-j9kg00qf 1195 39 oxygenation oxygenation NN cord-022526-j9kg00qf 1195 40 similar similar JJ cord-022526-j9kg00qf 1195 41 to to IN cord-022526-j9kg00qf 1195 42 that that DT cord-022526-j9kg00qf 1195 43 which which WDT cord-022526-j9kg00qf 1195 44 would would MD cord-022526-j9kg00qf 1195 45 be be VB cord-022526-j9kg00qf 1195 46 expected expect VBN cord-022526-j9kg00qf 1195 47 with with IN cord-022526-j9kg00qf 1195 48 low low JJ cord-022526-j9kg00qf 1195 49 - - HYPH cord-022526-j9kg00qf 1195 50 flow flow NN cord-022526-j9kg00qf 1195 51 ischemia ischemia NN cord-022526-j9kg00qf 1195 52 . . . cord-022526-j9kg00qf 1196 1 78 78 CD cord-022526-j9kg00qf 1196 2 , , , cord-022526-j9kg00qf 1196 3 79 79 CD cord-022526-j9kg00qf 1197 1 In in IN cord-022526-j9kg00qf 1197 2 particular particular JJ cord-022526-j9kg00qf 1197 3 , , , cord-022526-j9kg00qf 1197 4 microscopic microscopic JJ cord-022526-j9kg00qf 1197 5 evaluation evaluation NN cord-022526-j9kg00qf 1197 6 of of IN cord-022526-j9kg00qf 1197 7 vasculature vasculature NN cord-022526-j9kg00qf 1197 8 revealed reveal VBN cord-022526-j9kg00qf 1197 9 capillary capillary JJ cord-022526-j9kg00qf 1197 10 endothelial endothelial JJ cord-022526-j9kg00qf 1197 11 cell cell NN cord-022526-j9kg00qf 1197 12 damage damage NN cord-022526-j9kg00qf 1197 13 and and CC cord-022526-j9kg00qf 1197 14 local local JJ cord-022526-j9kg00qf 1197 15 edema edema NN cord-022526-j9kg00qf 1197 16 formation formation NN cord-022526-j9kg00qf 1197 17 . . . cord-022526-j9kg00qf 1198 1 80 80 CD cord-022526-j9kg00qf 1199 1 This this DT cord-022526-j9kg00qf 1199 2 data datum NNS cord-022526-j9kg00qf 1199 3 suggest suggest VBP cord-022526-j9kg00qf 1199 4 that that IN cord-022526-j9kg00qf 1199 5 distended distend VBN cord-022526-j9kg00qf 1199 6 intestine intestine NN cord-022526-j9kg00qf 1199 7 proximal proximal JJ cord-022526-j9kg00qf 1199 8 to to IN cord-022526-j9kg00qf 1199 9 an an DT cord-022526-j9kg00qf 1199 10 obstruction obstruction NN cord-022526-j9kg00qf 1199 11 may may MD cord-022526-j9kg00qf 1199 12 undergo undergo VB cord-022526-j9kg00qf 1199 13 mucosal mucosal JJ cord-022526-j9kg00qf 1199 14 injury injury NN cord-022526-j9kg00qf 1199 15 despite despite IN cord-022526-j9kg00qf 1199 16 its -PRON- PRP$ cord-022526-j9kg00qf 1199 17 normal normal JJ cord-022526-j9kg00qf 1199 18 appearance appearance NN cord-022526-j9kg00qf 1199 19 . . . cord-022526-j9kg00qf 1200 1 Indeed indeed RB cord-022526-j9kg00qf 1200 2 , , , cord-022526-j9kg00qf 1200 3 in in IN cord-022526-j9kg00qf 1200 4 one one CD cord-022526-j9kg00qf 1200 5 study study NN cord-022526-j9kg00qf 1200 6 , , , cord-022526-j9kg00qf 1200 7 intraluminal intraluminal JJ cord-022526-j9kg00qf 1200 8 pressures pressure NNS cord-022526-j9kg00qf 1200 9 greater great JJR cord-022526-j9kg00qf 1200 10 than than IN cord-022526-j9kg00qf 1200 11 15 15 CD cord-022526-j9kg00qf 1200 12 cm cm NN cord-022526-j9kg00qf 1200 13 H h NN cord-022526-j9kg00qf 1200 14 2 2 CD cord-022526-j9kg00qf 1200 15 O o NN cord-022526-j9kg00qf 1200 16 in in IN cord-022526-j9kg00qf 1200 17 naturally naturally RB cord-022526-j9kg00qf 1200 18 occurring occur VBG cord-022526-j9kg00qf 1200 19 cases case NNS cord-022526-j9kg00qf 1200 20 of of IN cord-022526-j9kg00qf 1200 21 colic colic NN cord-022526-j9kg00qf 1200 22 correlated correlate VBN cord-022526-j9kg00qf 1200 23 with with IN cord-022526-j9kg00qf 1200 24 a a DT cord-022526-j9kg00qf 1200 25 poor poor JJ cord-022526-j9kg00qf 1200 26 prognosis prognosis NN cord-022526-j9kg00qf 1200 27 for for IN cord-022526-j9kg00qf 1200 28 survival survival NN cord-022526-j9kg00qf 1200 29 . . . cord-022526-j9kg00qf 1201 1 81 81 CD cord-022526-j9kg00qf 1201 2 _SP cord-022526-j9kg00qf 1202 1 Although although IN cord-022526-j9kg00qf 1202 2 that that DT cord-022526-j9kg00qf 1202 3 reperfusion reperfusion NN cord-022526-j9kg00qf 1202 4 of of IN cord-022526-j9kg00qf 1202 5 ischemic ischemic JJ cord-022526-j9kg00qf 1202 6 tissues tissue NNS cord-022526-j9kg00qf 1202 7 results result NNS cord-022526-j9kg00qf 1202 8 in in IN cord-022526-j9kg00qf 1202 9 exacerbation exacerbation NN cord-022526-j9kg00qf 1202 10 of of IN cord-022526-j9kg00qf 1202 11 mucosal mucosal JJ cord-022526-j9kg00qf 1202 12 injury injury NN cord-022526-j9kg00qf 1202 13 recently recently RB cord-022526-j9kg00qf 1202 14 has have VBZ cord-022526-j9kg00qf 1202 15 been be VBN cord-022526-j9kg00qf 1202 16 taken take VBN cord-022526-j9kg00qf 1202 17 for for IN cord-022526-j9kg00qf 1202 18 granted grant VBN cord-022526-j9kg00qf 1202 19 , , , cord-022526-j9kg00qf 1202 20 one one PRP cord-022526-j9kg00qf 1202 21 should should MD cord-022526-j9kg00qf 1202 22 remember remember VB cord-022526-j9kg00qf 1202 23 that that IN cord-022526-j9kg00qf 1202 24 mechanisms mechanism NNS cord-022526-j9kg00qf 1202 25 underlying underlie VBG cord-022526-j9kg00qf 1202 26 intestinal intestinal JJ cord-022526-j9kg00qf 1202 27 reperfusion reperfusion NN cord-022526-j9kg00qf 1202 28 injury injury NN cord-022526-j9kg00qf 1202 29 have have VBP cord-022526-j9kg00qf 1202 30 been be VBN cord-022526-j9kg00qf 1202 31 defined define VBN cord-022526-j9kg00qf 1202 32 largely largely RB cord-022526-j9kg00qf 1202 33 in in IN cord-022526-j9kg00qf 1202 34 laboratory laboratory NN cord-022526-j9kg00qf 1202 35 animals animal NNS cord-022526-j9kg00qf 1202 36 under under IN cord-022526-j9kg00qf 1202 37 specific specific JJ cord-022526-j9kg00qf 1202 38 conditions condition NNS cord-022526-j9kg00qf 1202 39 . . . cord-022526-j9kg00qf 1203 1 [ [ -LRB- cord-022526-j9kg00qf 1203 2 82 82 CD cord-022526-j9kg00qf 1203 3 ] ] -RRB- cord-022526-j9kg00qf 1203 4 [ [ -LRB- cord-022526-j9kg00qf 1203 5 83 83 CD cord-022526-j9kg00qf 1203 6 ] ] -RRB- cord-022526-j9kg00qf 1204 1 [ [ -LRB- cord-022526-j9kg00qf 1204 2 84 84 CD cord-022526-j9kg00qf 1204 3 ] ] -RRB- cord-022526-j9kg00qf 1204 4 [ [ -LRB- cord-022526-j9kg00qf 1204 5 85 85 CD cord-022526-j9kg00qf 1204 6 ] ] -RRB- cord-022526-j9kg00qf 1204 7 [ [ -LRB- cord-022526-j9kg00qf 1204 8 86 86 CD cord-022526-j9kg00qf 1204 9 ] ] -RRB- cord-022526-j9kg00qf 1205 1 However however RB cord-022526-j9kg00qf 1205 2 , , , cord-022526-j9kg00qf 1205 3 studies study NNS cord-022526-j9kg00qf 1205 4 on on IN cord-022526-j9kg00qf 1205 5 reperfusion reperfusion NN cord-022526-j9kg00qf 1205 6 injury injury NN cord-022526-j9kg00qf 1205 7 in in IN cord-022526-j9kg00qf 1205 8 horses horse NNS cord-022526-j9kg00qf 1205 9 have have VBP cord-022526-j9kg00qf 1205 10 had have VBN cord-022526-j9kg00qf 1205 11 some some DT cord-022526-j9kg00qf 1205 12 conflicting conflicting JJ cord-022526-j9kg00qf 1205 13 results result NNS cord-022526-j9kg00qf 1205 14 . . . cord-022526-j9kg00qf 1206 1 68 68 CD cord-022526-j9kg00qf 1206 2 , , , cord-022526-j9kg00qf 1206 3 76 76 CD cord-022526-j9kg00qf 1206 4 , , , cord-022526-j9kg00qf 1206 5 87 87 CD cord-022526-j9kg00qf 1207 1 The the DT cord-022526-j9kg00qf 1207 2 conflict conflict NN cord-022526-j9kg00qf 1207 3 may may MD cord-022526-j9kg00qf 1207 4 be be VB cord-022526-j9kg00qf 1207 5 attributable attributable JJ cord-022526-j9kg00qf 1207 6 to to IN cord-022526-j9kg00qf 1207 7 the the DT cord-022526-j9kg00qf 1207 8 way way NN cord-022526-j9kg00qf 1207 9 in in IN cord-022526-j9kg00qf 1207 10 which which WDT cord-022526-j9kg00qf 1207 11 the the DT cord-022526-j9kg00qf 1207 12 studies study NNS cord-022526-j9kg00qf 1207 13 have have VBP cord-022526-j9kg00qf 1207 14 been be VBN cord-022526-j9kg00qf 1207 15 performed perform VBN cord-022526-j9kg00qf 1207 16 . . . cord-022526-j9kg00qf 1208 1 In in IN cord-022526-j9kg00qf 1208 2 particular particular JJ cord-022526-j9kg00qf 1208 3 , , , cord-022526-j9kg00qf 1208 4 the the DT cord-022526-j9kg00qf 1208 5 type type NN cord-022526-j9kg00qf 1208 6 of of IN cord-022526-j9kg00qf 1208 7 ischemia ischemia NN cord-022526-j9kg00qf 1208 8 used use VBN cord-022526-j9kg00qf 1208 9 in in IN cord-022526-j9kg00qf 1208 10 most most JJS cord-022526-j9kg00qf 1208 11 laboratory laboratory NN cord-022526-j9kg00qf 1208 12 animal animal NN cord-022526-j9kg00qf 1208 13 studies study NNS cord-022526-j9kg00qf 1208 14 has have VBZ cord-022526-j9kg00qf 1208 15 been be VBN cord-022526-j9kg00qf 1208 16 low low JJ cord-022526-j9kg00qf 1208 17 - - HYPH cord-022526-j9kg00qf 1208 18 flow flow NN cord-022526-j9kg00qf 1208 19 ischemia ischemia NN cord-022526-j9kg00qf 1208 20 ( ( -LRB- cord-022526-j9kg00qf 1208 21 in in IN cord-022526-j9kg00qf 1208 22 which which WDT cord-022526-j9kg00qf 1208 23 the the DT cord-022526-j9kg00qf 1208 24 blood blood NN cord-022526-j9kg00qf 1208 25 flow flow NN cord-022526-j9kg00qf 1208 26 typically typically RB cord-022526-j9kg00qf 1208 27 is be VBZ cord-022526-j9kg00qf 1208 28 reduced reduce VBN cord-022526-j9kg00qf 1208 29 to to IN cord-022526-j9kg00qf 1208 30 20 20 CD cord-022526-j9kg00qf 1208 31 % % NN cord-022526-j9kg00qf 1208 32 of of IN cord-022526-j9kg00qf 1208 33 baseline baseline JJ cord-022526-j9kg00qf 1208 34 flow flow NN cord-022526-j9kg00qf 1208 35 ) ) -RRB- cord-022526-j9kg00qf 1208 36 , , , cord-022526-j9kg00qf 1208 37 whereas whereas IN cord-022526-j9kg00qf 1208 38 studies study NNS cord-022526-j9kg00qf 1208 39 in in IN cord-022526-j9kg00qf 1208 40 horses horse NNS cord-022526-j9kg00qf 1208 41 have have VBP cord-022526-j9kg00qf 1208 42 used use VBN cord-022526-j9kg00qf 1208 43 a a DT cord-022526-j9kg00qf 1208 44 number number NN cord-022526-j9kg00qf 1208 45 of of IN cord-022526-j9kg00qf 1208 46 different different JJ cord-022526-j9kg00qf 1208 47 ischemic ischemic JJ cord-022526-j9kg00qf 1208 48 models model NNS cord-022526-j9kg00qf 1208 49 , , , cord-022526-j9kg00qf 1208 50 including include VBG cord-022526-j9kg00qf 1208 51 various various JJ cord-022526-j9kg00qf 1208 52 types type NNS cord-022526-j9kg00qf 1208 53 of of IN cord-022526-j9kg00qf 1208 54 strangulating strangulating JJ cord-022526-j9kg00qf 1208 55 obstruction obstruction NN cord-022526-j9kg00qf 1208 56 . . . cord-022526-j9kg00qf 1209 1 Although although IN cord-022526-j9kg00qf 1209 2 strangulating strangulating JJ cord-022526-j9kg00qf 1209 3 obstruction obstruction NN cord-022526-j9kg00qf 1209 4 is be VBZ cord-022526-j9kg00qf 1209 5 of of IN cord-022526-j9kg00qf 1209 6 great great JJ cord-022526-j9kg00qf 1209 7 clinical clinical JJ cord-022526-j9kg00qf 1209 8 relevance relevance NN cord-022526-j9kg00qf 1209 9 , , , cord-022526-j9kg00qf 1209 10 this this DT cord-022526-j9kg00qf 1209 11 type type NN cord-022526-j9kg00qf 1209 12 of of IN cord-022526-j9kg00qf 1209 13 ischemic ischemic JJ cord-022526-j9kg00qf 1209 14 insult insult NN cord-022526-j9kg00qf 1209 15 is be VBZ cord-022526-j9kg00qf 1209 16 less less RBR cord-022526-j9kg00qf 1209 17 likely likely JJ cord-022526-j9kg00qf 1209 18 to to TO cord-022526-j9kg00qf 1209 19 develop develop VB cord-022526-j9kg00qf 1209 20 reperfusion reperfusion NN cord-022526-j9kg00qf 1209 21 injury injury NN cord-022526-j9kg00qf 1209 22 . . . cord-022526-j9kg00qf 1210 1 68 68 CD cord-022526-j9kg00qf 1210 2 , , , cord-022526-j9kg00qf 1210 3 88 88 CD cord-022526-j9kg00qf 1210 4 , , , cord-022526-j9kg00qf 1210 5 89 89 CD cord-022526-j9kg00qf 1211 1 Conversely conversely RB cord-022526-j9kg00qf 1211 2 , , , cord-022526-j9kg00qf 1211 3 low low JJ cord-022526-j9kg00qf 1211 4 - - HYPH cord-022526-j9kg00qf 1211 5 flow flow NN cord-022526-j9kg00qf 1211 6 ischemia ischemia NN cord-022526-j9kg00qf 1211 7 appears appear VBZ cord-022526-j9kg00qf 1211 8 to to IN cord-022526-j9kg00qf 1211 9 prime prime JJ cord-022526-j9kg00qf 1211 10 tissues tissue NNS cord-022526-j9kg00qf 1211 11 for for IN cord-022526-j9kg00qf 1211 12 subsequent subsequent JJ cord-022526-j9kg00qf 1211 13 injury injury NN cord-022526-j9kg00qf 1211 14 once once IN cord-022526-j9kg00qf 1211 15 the the DT cord-022526-j9kg00qf 1211 16 tissue tissue NN cord-022526-j9kg00qf 1211 17 is be VBZ cord-022526-j9kg00qf 1211 18 reperfused reperfuse VBN cord-022526-j9kg00qf 1211 19 , , , cord-022526-j9kg00qf 1211 20 and and CC cord-022526-j9kg00qf 1211 21 considerable considerable JJ cord-022526-j9kg00qf 1211 22 evidence evidence NN cord-022526-j9kg00qf 1211 23 supports support VBZ cord-022526-j9kg00qf 1211 24 the the DT cord-022526-j9kg00qf 1211 25 presence presence NN cord-022526-j9kg00qf 1211 26 of of IN cord-022526-j9kg00qf 1211 27 reperfusion reperfusion NN cord-022526-j9kg00qf 1211 28 injury injury NN cord-022526-j9kg00qf 1211 29 in in IN cord-022526-j9kg00qf 1211 30 horses horse NNS cord-022526-j9kg00qf 1211 31 following follow VBG cord-022526-j9kg00qf 1211 32 low low JJ cord-022526-j9kg00qf 1211 33 - - HYPH cord-022526-j9kg00qf 1211 34 flow flow NN cord-022526-j9kg00qf 1211 35 ischemia ischemia NN cord-022526-j9kg00qf 1211 36 . . . cord-022526-j9kg00qf 1212 1 75 75 CD cord-022526-j9kg00qf 1212 2 , , , cord-022526-j9kg00qf 1212 3 76 76 CD cord-022526-j9kg00qf 1212 4 , , , cord-022526-j9kg00qf 1212 5 80 80 CD cord-022526-j9kg00qf 1212 6 , , , cord-022526-j9kg00qf 1212 7 90 90 CD cord-022526-j9kg00qf 1213 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 1213 2 , , , cord-022526-j9kg00qf 1213 3 lowflow lowflow NNP cord-022526-j9kg00qf 1213 4 ischemia ischemia NN cord-022526-j9kg00qf 1213 5 may may MD cord-022526-j9kg00qf 1213 6 not not RB cord-022526-j9kg00qf 1213 7 be be VB cord-022526-j9kg00qf 1213 8 a a DT cord-022526-j9kg00qf 1213 9 common common JJ cord-022526-j9kg00qf 1213 10 clinical clinical JJ cord-022526-j9kg00qf 1213 11 entity entity NN cord-022526-j9kg00qf 1213 12 . . . cord-022526-j9kg00qf 1214 1 In in IN cord-022526-j9kg00qf 1214 2 addition addition NN cord-022526-j9kg00qf 1214 3 to to IN cord-022526-j9kg00qf 1214 4 the the DT cord-022526-j9kg00qf 1214 5 type type NN cord-022526-j9kg00qf 1214 6 of of IN cord-022526-j9kg00qf 1214 7 ischemia ischemia NN cord-022526-j9kg00qf 1214 8 , , , cord-022526-j9kg00qf 1214 9 other other JJ cord-022526-j9kg00qf 1214 10 factors factor NNS cord-022526-j9kg00qf 1214 11 are be VBP cord-022526-j9kg00qf 1214 12 involved involve VBN cord-022526-j9kg00qf 1214 13 in in IN cord-022526-j9kg00qf 1214 14 priming prime VBG cord-022526-j9kg00qf 1214 15 tissues tissue NNS cord-022526-j9kg00qf 1214 16 for for IN cord-022526-j9kg00qf 1214 17 reperfusion reperfusion NN cord-022526-j9kg00qf 1214 18 injury injury NN cord-022526-j9kg00qf 1214 19 , , , cord-022526-j9kg00qf 1214 20 including include VBG cord-022526-j9kg00qf 1214 21 species specie NNS cord-022526-j9kg00qf 1214 22 and and CC cord-022526-j9kg00qf 1214 23 anatomic anatomic JJ cord-022526-j9kg00qf 1214 24 - - HYPH cord-022526-j9kg00qf 1214 25 specific specific JJ cord-022526-j9kg00qf 1214 26 variation variation NN cord-022526-j9kg00qf 1214 27 in in IN cord-022526-j9kg00qf 1214 28 oxidant oxidant JJ cord-022526-j9kg00qf 1214 29 enzyme enzyme NN cord-022526-j9kg00qf 1214 30 and and CC cord-022526-j9kg00qf 1214 31 neutrophil neutrophil NN cord-022526-j9kg00qf 1214 32 levels level NNS cord-022526-j9kg00qf 1214 33 ( ( -LRB- cord-022526-j9kg00qf 1214 34 Table table NN cord-022526-j9kg00qf 1214 35 13 13 CD cord-022526-j9kg00qf 1214 36 .5 .5 CD cord-022526-j9kg00qf 1214 37 - - SYM cord-022526-j9kg00qf 1214 38 2 2 CD cord-022526-j9kg00qf 1214 39 ) ) -RRB- cord-022526-j9kg00qf 1214 40 . . . cord-022526-j9kg00qf 1215 1 For for IN cord-022526-j9kg00qf 1215 2 example example NN cord-022526-j9kg00qf 1215 3 , , , cord-022526-j9kg00qf 1215 4 the the DT cord-022526-j9kg00qf 1215 5 foal foal NN cord-022526-j9kg00qf 1215 6 appears appear VBZ cord-022526-j9kg00qf 1215 7 to to TO cord-022526-j9kg00qf 1215 8 have have VB cord-022526-j9kg00qf 1215 9 low low JJ cord-022526-j9kg00qf 1215 10 levels level NNS cord-022526-j9kg00qf 1215 11 of of IN cord-022526-j9kg00qf 1215 12 small small JJ cord-022526-j9kg00qf 1215 13 intestinal intestinal JJ cord-022526-j9kg00qf 1215 14 xanthine xanthine NN cord-022526-j9kg00qf 1215 15 oxidase oxidase NN cord-022526-j9kg00qf 1215 16 , , , cord-022526-j9kg00qf 1215 17 an an DT cord-022526-j9kg00qf 1215 18 enzyme enzyme NN cord-022526-j9kg00qf 1215 19 that that WDT cord-022526-j9kg00qf 1215 20 has have VBZ cord-022526-j9kg00qf 1215 21 been be VBN cord-022526-j9kg00qf 1215 22 shown show VBN cord-022526-j9kg00qf 1215 23 to to TO cord-022526-j9kg00qf 1215 24 play play VB cord-022526-j9kg00qf 1215 25 a a DT cord-022526-j9kg00qf 1215 26 critical critical JJ cord-022526-j9kg00qf 1215 27 role role NN cord-022526-j9kg00qf 1215 28 in in IN cord-022526-j9kg00qf 1215 29 triggering trigger VBG cord-022526-j9kg00qf 1215 30 reperfusion reperfusion NN cord-022526-j9kg00qf 1215 31 injury injury NN cord-022526-j9kg00qf 1215 32 in in IN cord-022526-j9kg00qf 1215 33 laboratory laboratory NN cord-022526-j9kg00qf 1215 34 animals animal NNS cord-022526-j9kg00qf 1215 35 , , , cord-022526-j9kg00qf 1215 36 84 84 CD cord-022526-j9kg00qf 1215 37 , , , cord-022526-j9kg00qf 1215 38 85 85 CD cord-022526-j9kg00qf 1215 39 , , , cord-022526-j9kg00qf 1215 40 91 91 CD cord-022526-j9kg00qf 1215 41 whereas whereas IN cord-022526-j9kg00qf 1215 42 adult adult NN cord-022526-j9kg00qf 1215 43 levels level NNS cord-022526-j9kg00qf 1215 44 are be VBP cord-022526-j9kg00qf 1215 45 much much RB cord-022526-j9kg00qf 1215 46 greater great JJR cord-022526-j9kg00qf 1215 47 , , , cord-022526-j9kg00qf 1215 48 particularly particularly RB cord-022526-j9kg00qf 1215 49 in in IN cord-022526-j9kg00qf 1215 50 the the DT cord-022526-j9kg00qf 1215 51 proximal proximal JJ cord-022526-j9kg00qf 1215 52 small small JJ cord-022526-j9kg00qf 1215 53 intestine intestine NN cord-022526-j9kg00qf 1215 54 . . . cord-022526-j9kg00qf 1216 1 92 92 CD cord-022526-j9kg00qf 1217 1 In in IN cord-022526-j9kg00qf 1217 2 addition addition NN cord-022526-j9kg00qf 1217 3 , , , cord-022526-j9kg00qf 1217 4 horses horse NNS cord-022526-j9kg00qf 1217 5 appear appear VBP cord-022526-j9kg00qf 1217 6 to to TO cord-022526-j9kg00qf 1217 7 have have VB cord-022526-j9kg00qf 1217 8 low low JJ cord-022526-j9kg00qf 1217 9 numbers number NNS cord-022526-j9kg00qf 1217 10 of of IN cord-022526-j9kg00qf 1217 11 resident resident JJ cord-022526-j9kg00qf 1217 12 neutrophils neutrophil NNS cord-022526-j9kg00qf 1217 13 in in IN cord-022526-j9kg00qf 1217 14 the the DT cord-022526-j9kg00qf 1217 15 intestinal intestinal JJ cord-022526-j9kg00qf 1217 16 mucosa mucosa NN cord-022526-j9kg00qf 1217 17 , , , cord-022526-j9kg00qf 1217 18 93 93 CD cord-022526-j9kg00qf 1217 19 and and CC cord-022526-j9kg00qf 1217 20 this this DT cord-022526-j9kg00qf 1217 21 population population NN cord-022526-j9kg00qf 1217 22 of of IN cord-022526-j9kg00qf 1217 23 neutrophils neutrophil NNS cord-022526-j9kg00qf 1217 24 ( ( -LRB- cord-022526-j9kg00qf 1217 25 rather rather RB cord-022526-j9kg00qf 1217 26 than than IN cord-022526-j9kg00qf 1217 27 those those DT cord-022526-j9kg00qf 1217 28 recruited recruit VBN cord-022526-j9kg00qf 1217 29 from from IN cord-022526-j9kg00qf 1217 30 the the DT cord-022526-j9kg00qf 1217 31 circulation circulation NN cord-022526-j9kg00qf 1217 32 ) ) -RRB- cord-022526-j9kg00qf 1217 33 appears appear VBZ cord-022526-j9kg00qf 1217 34 to to TO cord-022526-j9kg00qf 1217 35 be be VB cord-022526-j9kg00qf 1217 36 most most RBS cord-022526-j9kg00qf 1217 37 critical critical JJ cord-022526-j9kg00qf 1217 38 for for IN cord-022526-j9kg00qf 1217 39 induction induction NN cord-022526-j9kg00qf 1217 40 of of IN cord-022526-j9kg00qf 1217 41 reperfusion reperfusion NN cord-022526-j9kg00qf 1217 42 injury injury NN cord-022526-j9kg00qf 1217 43 . . . cord-022526-j9kg00qf 1218 1 86 86 CD cord-022526-j9kg00qf 1219 1 However however RB cord-022526-j9kg00qf 1219 2 , , , cord-022526-j9kg00qf 1219 3 studies study NNS cord-022526-j9kg00qf 1219 4 demonstrating demonstrate VBG cord-022526-j9kg00qf 1219 5 reperfusion reperfusion NN cord-022526-j9kg00qf 1219 6 injury injury NN cord-022526-j9kg00qf 1219 7 in in IN cord-022526-j9kg00qf 1219 8 the the DT cord-022526-j9kg00qf 1219 9 equine equine JJ cord-022526-j9kg00qf 1219 10 colon colon NN cord-022526-j9kg00qf 1219 11 following follow VBG cord-022526-j9kg00qf 1219 12 low low JJ cord-022526-j9kg00qf 1219 13 - - HYPH cord-022526-j9kg00qf 1219 14 flow flow NN cord-022526-j9kg00qf 1219 15 ischemia ischemia NN cord-022526-j9kg00qf 1219 16 have have VBP cord-022526-j9kg00qf 1219 17 shown show VBN cord-022526-j9kg00qf 1219 18 significant significant JJ cord-022526-j9kg00qf 1219 19 accumulation accumulation NN cord-022526-j9kg00qf 1219 20 of of IN cord-022526-j9kg00qf 1219 21 neutrophils neutrophil NNS cord-022526-j9kg00qf 1219 22 within within IN cord-022526-j9kg00qf 1219 23 the the DT cord-022526-j9kg00qf 1219 24 mucosa mucosa NN cord-022526-j9kg00qf 1219 25 . . . cord-022526-j9kg00qf 1220 1 75 75 CD cord-022526-j9kg00qf 1221 1 Therefore therefore RB cord-022526-j9kg00qf 1221 2 a a DT cord-022526-j9kg00qf 1221 3 complete complete JJ cord-022526-j9kg00qf 1221 4 understanding understanding NN cord-022526-j9kg00qf 1221 5 of of IN cord-022526-j9kg00qf 1221 6 mechanisms mechanism NNS cord-022526-j9kg00qf 1221 7 of of IN cord-022526-j9kg00qf 1221 8 neutrophilic neutrophilic JJ cord-022526-j9kg00qf 1221 9 infiltration infiltration NN cord-022526-j9kg00qf 1221 10 and and CC cord-022526-j9kg00qf 1221 11 the the DT cord-022526-j9kg00qf 1221 12 mechanisms mechanism NNS cord-022526-j9kg00qf 1221 13 whereby whereby WRB cord-022526-j9kg00qf 1221 14 they -PRON- PRP cord-022526-j9kg00qf 1221 15 damage damage VBP cord-022526-j9kg00qf 1221 16 tissue tissue NN cord-022526-j9kg00qf 1221 17 requires require VBZ cord-022526-j9kg00qf 1221 18 further further JJ cord-022526-j9kg00qf 1221 19 study study NN cord-022526-j9kg00qf 1221 20 . . . cord-022526-j9kg00qf 1222 1 Reperfusion reperfusion NN cord-022526-j9kg00qf 1222 2 injury injury NN cord-022526-j9kg00qf 1222 3 is be VBZ cord-022526-j9kg00qf 1222 4 initiated initiate VBN cord-022526-j9kg00qf 1222 5 during during IN cord-022526-j9kg00qf 1222 6 ischemia ischemia NN cord-022526-j9kg00qf 1222 7 when when WRB cord-022526-j9kg00qf 1222 8 the the DT cord-022526-j9kg00qf 1222 9 enzyme enzyme NN cord-022526-j9kg00qf 1222 10 xanthine xanthine NN cord-022526-j9kg00qf 1222 11 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 1222 12 is be VBZ cord-022526-j9kg00qf 1222 13 converted convert VBN cord-022526-j9kg00qf 1222 14 to to IN cord-022526-j9kg00qf 1222 15 xanthine xanthine NN cord-022526-j9kg00qf 1222 16 oxidase oxidase NN cord-022526-j9kg00qf 1222 17 and and CC cord-022526-j9kg00qf 1222 18 when when WRB cord-022526-j9kg00qf 1222 19 its -PRON- PRP$ cord-022526-j9kg00qf 1222 20 substrate substrate NN cord-022526-j9kg00qf 1222 21 , , , cord-022526-j9kg00qf 1222 22 hypoxanthine hypoxanthine NNP cord-022526-j9kg00qf 1222 23 , , , cord-022526-j9kg00qf 1222 24 accumulates accumulate VBZ cord-022526-j9kg00qf 1222 25 simultaneously simultaneously RB cord-022526-j9kg00qf 1222 26 because because IN cord-022526-j9kg00qf 1222 27 of of IN cord-022526-j9kg00qf 1222 28 ATP ATP NNP cord-022526-j9kg00qf 1222 29 use use NN cord-022526-j9kg00qf 1222 30 ( ( -LRB- cord-022526-j9kg00qf 1222 31 Figure figure NN cord-022526-j9kg00qf 1222 32 13 13 CD cord-022526-j9kg00qf 1222 33 .5 .5 CD cord-022526-j9kg00qf 1222 34 - - SYM cord-022526-j9kg00qf 1222 35 2 2 CD cord-022526-j9kg00qf 1222 36 ) ) -RRB- cord-022526-j9kg00qf 1222 37 . . . cord-022526-j9kg00qf 1223 1 57 57 CD cord-022526-j9kg00qf 1223 2 , , , cord-022526-j9kg00qf 1223 3 94 94 CD cord-022526-j9kg00qf 1224 1 However however RB cord-022526-j9kg00qf 1224 2 , , , cord-022526-j9kg00qf 1224 3 little little JJ cord-022526-j9kg00qf 1224 4 xanthine xanthine NN cord-022526-j9kg00qf 1224 5 oxidase oxidase NN cord-022526-j9kg00qf 1224 6 activity activity NN cord-022526-j9kg00qf 1224 7 occurs occur VBZ cord-022526-j9kg00qf 1224 8 during during IN cord-022526-j9kg00qf 1224 9 ischemia ischemia NN cord-022526-j9kg00qf 1224 10 , , , cord-022526-j9kg00qf 1224 11 because because IN cord-022526-j9kg00qf 1224 12 oxygen oxygen NN cord-022526-j9kg00qf 1224 13 is be VBZ cord-022526-j9kg00qf 1224 14 required require VBN cord-022526-j9kg00qf 1224 15 as as IN cord-022526-j9kg00qf 1224 16 an an DT cord-022526-j9kg00qf 1224 17 electron electron NN cord-022526-j9kg00qf 1224 18 acceptor acceptor NN cord-022526-j9kg00qf 1224 19 . . . cord-022526-j9kg00qf 1225 1 During during IN cord-022526-j9kg00qf 1225 2 reperfusion reperfusion NN cord-022526-j9kg00qf 1225 3 , , , cord-022526-j9kg00qf 1225 4 xanthine xanthine NN cord-022526-j9kg00qf 1225 5 oxidase oxidase NN cord-022526-j9kg00qf 1225 6 rapidly rapidly RB cord-022526-j9kg00qf 1225 7 degrades degrade VBZ cord-022526-j9kg00qf 1225 8 hypoxanthine hypoxanthine NN cord-022526-j9kg00qf 1225 9 in in IN cord-022526-j9kg00qf 1225 10 the the DT cord-022526-j9kg00qf 1225 11 presence presence NN cord-022526-j9kg00qf 1225 12 of of IN cord-022526-j9kg00qf 1225 13 oxygen oxygen NN cord-022526-j9kg00qf 1225 14 , , , cord-022526-j9kg00qf 1225 15 producing produce VBG cord-022526-j9kg00qf 1225 16 the the DT cord-022526-j9kg00qf 1225 17 superoxide superoxide NN cord-022526-j9kg00qf 1225 18 radical radical JJ cord-022526-j9kg00qf 1225 19 as as IN cord-022526-j9kg00qf 1225 20 a a DT cord-022526-j9kg00qf 1225 21 by by IN cord-022526-j9kg00qf 1225 22 - - HYPH cord-022526-j9kg00qf 1225 23 product product NN cord-022526-j9kg00qf 1225 24 . . . cord-022526-j9kg00qf 1226 1 57 57 CD cord-022526-j9kg00qf 1227 1 The the DT cord-022526-j9kg00qf 1227 2 superoxide superoxide NN cord-022526-j9kg00qf 1227 3 radical radical JJ cord-022526-j9kg00qf 1227 4 contributes contribute VBZ cord-022526-j9kg00qf 1227 5 to to IN cord-022526-j9kg00qf 1227 6 oxidative oxidative JJ cord-022526-j9kg00qf 1227 7 tissue tissue NN cord-022526-j9kg00qf 1227 8 damage damage NN cord-022526-j9kg00qf 1227 9 and and CC cord-022526-j9kg00qf 1227 10 , , , cord-022526-j9kg00qf 1227 11 most most RBS cord-022526-j9kg00qf 1227 12 importantly importantly RB cord-022526-j9kg00qf 1227 13 , , , cord-022526-j9kg00qf 1227 14 activates activate VBZ cord-022526-j9kg00qf 1227 15 neutrophil neutrophil NN cord-022526-j9kg00qf 1227 16 chemoattractants chemoattractant NNS cord-022526-j9kg00qf 1227 17 . . . cord-022526-j9kg00qf 1228 1 84 84 CD cord-022526-j9kg00qf 1228 2 , , , cord-022526-j9kg00qf 1228 3 85 85 CD cord-022526-j9kg00qf 1229 1 Thus thus RB cord-022526-j9kg00qf 1229 2 inhibition inhibition NN cord-022526-j9kg00qf 1229 3 of of IN cord-022526-j9kg00qf 1229 4 xanthine xanthine NN cord-022526-j9kg00qf 1229 5 oxidase oxidase NN cord-022526-j9kg00qf 1229 6 in in IN cord-022526-j9kg00qf 1229 7 feline feline JJ cord-022526-j9kg00qf 1229 8 studies study NNS cord-022526-j9kg00qf 1229 9 of of IN cord-022526-j9kg00qf 1229 10 intestinal intestinal JJ cord-022526-j9kg00qf 1229 11 ischemiareperfusion ischemiareperfusion NNP cord-022526-j9kg00qf 1229 12 injury injury NN cord-022526-j9kg00qf 1229 13 prevents prevent VBZ cord-022526-j9kg00qf 1229 14 infiltration infiltration NN cord-022526-j9kg00qf 1229 15 of of IN cord-022526-j9kg00qf 1229 16 neutrophils neutrophil NNS cord-022526-j9kg00qf 1229 17 and and CC cord-022526-j9kg00qf 1229 18 subsequent subsequent JJ cord-022526-j9kg00qf 1229 19 mucosal mucosal JJ cord-022526-j9kg00qf 1229 20 injury injury NN cord-022526-j9kg00qf 1229 21 . . . cord-022526-j9kg00qf 1230 1 83 83 CD cord-022526-j9kg00qf 1230 2 , , , cord-022526-j9kg00qf 1230 3 84 84 CD cord-022526-j9kg00qf 1231 1 However however RB cord-022526-j9kg00qf 1231 2 , , , cord-022526-j9kg00qf 1231 3 inhibition inhibition NN cord-022526-j9kg00qf 1231 4 of of IN cord-022526-j9kg00qf 1231 5 xanthine xanthine NN cord-022526-j9kg00qf 1231 6 oxidase oxidase NN cord-022526-j9kg00qf 1231 7 has have VBZ cord-022526-j9kg00qf 1231 8 had have VBN cord-022526-j9kg00qf 1231 9 no no DT cord-022526-j9kg00qf 1231 10 effect effect NN cord-022526-j9kg00qf 1231 11 on on IN cord-022526-j9kg00qf 1231 12 ischemiareperfusion ischemiareperfusion NN cord-022526-j9kg00qf 1231 13 injury injury NN cord-022526-j9kg00qf 1231 14 in in IN cord-022526-j9kg00qf 1231 15 equine equine JJ cord-022526-j9kg00qf 1231 16 small small JJ cord-022526-j9kg00qf 1231 17 intestine intestine NN cord-022526-j9kg00qf 1231 18 87 87 CD cord-022526-j9kg00qf 1231 19 and and CC cord-022526-j9kg00qf 1231 20 colon colon NN cord-022526-j9kg00qf 1231 21 , , , cord-022526-j9kg00qf 1231 22 95 95 CD cord-022526-j9kg00qf 1231 23 suggesting suggest VBG cord-022526-j9kg00qf 1231 24 that that IN cord-022526-j9kg00qf 1231 25 reperfusion reperfusion NN cord-022526-j9kg00qf 1231 26 injury injury NN cord-022526-j9kg00qf 1231 27 is be VBZ cord-022526-j9kg00qf 1231 28 simply simply RB cord-022526-j9kg00qf 1231 29 a a DT cord-022526-j9kg00qf 1231 30 continuation continuation NN cord-022526-j9kg00qf 1231 31 of of IN cord-022526-j9kg00qf 1231 32 injury injury NN cord-022526-j9kg00qf 1231 33 initiated initiate VBN cord-022526-j9kg00qf 1231 34 during during IN cord-022526-j9kg00qf 1231 35 ischemia ischemia NN cord-022526-j9kg00qf 1231 36 , , , cord-022526-j9kg00qf 1231 37 as as IN cord-022526-j9kg00qf 1231 38 suggested suggest VBN cord-022526-j9kg00qf 1231 39 in in IN cord-022526-j9kg00qf 1231 40 some some DT cord-022526-j9kg00qf 1231 41 equine equine JJ cord-022526-j9kg00qf 1231 42 studies study NNS cord-022526-j9kg00qf 1231 43 , , , cord-022526-j9kg00qf 1231 44 63 63 CD cord-022526-j9kg00qf 1231 45 or or CC cord-022526-j9kg00qf 1231 46 that that IN cord-022526-j9kg00qf 1231 47 the the DT cord-022526-j9kg00qf 1231 48 classic classic JJ cord-022526-j9kg00qf 1231 49 reperfusion reperfusion NN cord-022526-j9kg00qf 1231 50 injury injury NN cord-022526-j9kg00qf 1231 51 pathway pathway NN cord-022526-j9kg00qf 1231 52 is be VBZ cord-022526-j9kg00qf 1231 53 activated activate VBN cord-022526-j9kg00qf 1231 54 by by IN cord-022526-j9kg00qf 1231 55 alternate alternate JJ cord-022526-j9kg00qf 1231 56 sources source NNS cord-022526-j9kg00qf 1231 57 of of IN cord-022526-j9kg00qf 1231 58 reactive reactive JJ cord-022526-j9kg00qf 1231 59 oxygen oxygen NN cord-022526-j9kg00qf 1231 60 metabolites metabolite NNS cord-022526-j9kg00qf 1231 61 . . . cord-022526-j9kg00qf 1232 1 The the DT cord-022526-j9kg00qf 1232 2 latter latter JJ cord-022526-j9kg00qf 1232 3 has have VBZ cord-022526-j9kg00qf 1232 4 been be VBN cord-022526-j9kg00qf 1232 5 suggested suggest VBN cord-022526-j9kg00qf 1232 6 by by IN cord-022526-j9kg00qf 1232 7 studies study NNS cord-022526-j9kg00qf 1232 8 in in IN cord-022526-j9kg00qf 1232 9 feline feline JJ cord-022526-j9kg00qf 1232 10 models model NNS cord-022526-j9kg00qf 1232 11 of of IN cord-022526-j9kg00qf 1232 12 ischemia ischemia NN cord-022526-j9kg00qf 1232 13 - - HYPH cord-022526-j9kg00qf 1232 14 reperfusion reperfusion NN cord-022526-j9kg00qf 1232 15 injury injury NN cord-022526-j9kg00qf 1232 16 in in IN cord-022526-j9kg00qf 1232 17 which which WDT cord-022526-j9kg00qf 1232 18 the the DT cord-022526-j9kg00qf 1232 19 source source NN cord-022526-j9kg00qf 1232 20 of of IN cord-022526-j9kg00qf 1232 21 a a DT cord-022526-j9kg00qf 1232 22 significant significant JJ cord-022526-j9kg00qf 1232 23 proportion proportion NN cord-022526-j9kg00qf 1232 24 of of IN cord-022526-j9kg00qf 1232 25 reactive reactive JJ cord-022526-j9kg00qf 1232 26 oxygen oxygen NN cord-022526-j9kg00qf 1232 27 metabolites metabolite NNS cord-022526-j9kg00qf 1232 28 is be VBZ cord-022526-j9kg00qf 1232 29 unknown unknown JJ cord-022526-j9kg00qf 1232 30 and and CC cord-022526-j9kg00qf 1232 31 is be VBZ cord-022526-j9kg00qf 1232 32 independent independent JJ cord-022526-j9kg00qf 1232 33 of of IN cord-022526-j9kg00qf 1232 34 xanthine xanthine NN cord-022526-j9kg00qf 1232 35 oxidase oxidase NN cord-022526-j9kg00qf 1232 36 and and CC cord-022526-j9kg00qf 1232 37 neutrophils neutrophil NNS cord-022526-j9kg00qf 1232 38 . . . cord-022526-j9kg00qf 1233 1 83 83 CD cord-022526-j9kg00qf 1234 1 A a DT cord-022526-j9kg00qf 1234 2 veterinary veterinary JJ cord-022526-j9kg00qf 1234 3 review review NN cord-022526-j9kg00qf 1234 4 of of IN cord-022526-j9kg00qf 1234 5 the the DT cord-022526-j9kg00qf 1234 6 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1234 7 of of IN cord-022526-j9kg00qf 1234 8 intestinal intestinal JJ cord-022526-j9kg00qf 1234 9 reperfusion reperfusion NN cord-022526-j9kg00qf 1234 10 injury injury NN cord-022526-j9kg00qf 1234 11 in in IN cord-022526-j9kg00qf 1234 12 the the DT cord-022526-j9kg00qf 1234 13 horse horse NN cord-022526-j9kg00qf 1234 14 suggested suggest VBD cord-022526-j9kg00qf 1234 15 the the DT cord-022526-j9kg00qf 1234 16 concept concept NN cord-022526-j9kg00qf 1234 17 of of IN cord-022526-j9kg00qf 1234 18 a a DT cord-022526-j9kg00qf 1234 19 therapeutic therapeutic JJ cord-022526-j9kg00qf 1234 20 window window NN cord-022526-j9kg00qf 1234 21 wherein wherein WRB cord-022526-j9kg00qf 1234 22 treatment treatment NN cord-022526-j9kg00qf 1234 23 of of IN cord-022526-j9kg00qf 1234 24 reperfusion reperfusion NN cord-022526-j9kg00qf 1234 25 injury injury NN cord-022526-j9kg00qf 1234 26 would would MD cord-022526-j9kg00qf 1234 27 be be VB cord-022526-j9kg00qf 1234 28 beneficial beneficial JJ cord-022526-j9kg00qf 1234 29 . . . cord-022526-j9kg00qf 1235 1 57 57 CD cord-022526-j9kg00qf 1236 1 The the DT cord-022526-j9kg00qf 1236 2 basis basis NN cord-022526-j9kg00qf 1236 3 of of IN cord-022526-j9kg00qf 1236 4 this this DT cord-022526-j9kg00qf 1236 5 concept concept NN cord-022526-j9kg00qf 1236 6 is be VBZ cord-022526-j9kg00qf 1236 7 that that IN cord-022526-j9kg00qf 1236 8 certain certain JJ cord-022526-j9kg00qf 1236 9 conditions condition NNS cord-022526-j9kg00qf 1236 10 exist exist VBP cord-022526-j9kg00qf 1236 11 under under IN cord-022526-j9kg00qf 1236 12 which which WDT cord-022526-j9kg00qf 1236 13 ischemic ischemic JJ cord-022526-j9kg00qf 1236 14 injury injury NN cord-022526-j9kg00qf 1236 15 is be VBZ cord-022526-j9kg00qf 1236 16 minimal minimal JJ cord-022526-j9kg00qf 1236 17 and and CC cord-022526-j9kg00qf 1236 18 that that IN cord-022526-j9kg00qf 1236 19 tissues tissue NNS cord-022526-j9kg00qf 1236 20 are be VBP cord-022526-j9kg00qf 1236 21 damaged damage VBN cord-022526-j9kg00qf 1236 22 severely severely RB cord-022526-j9kg00qf 1236 23 during during IN cord-022526-j9kg00qf 1236 24 reperfusion reperfusion NN cord-022526-j9kg00qf 1236 25 . . . cord-022526-j9kg00qf 1237 1 88 88 CD cord-022526-j9kg00qf 1238 1 Thus thus RB cord-022526-j9kg00qf 1238 2 under under IN cord-022526-j9kg00qf 1238 3 conditions condition NNS cord-022526-j9kg00qf 1238 4 of of IN cord-022526-j9kg00qf 1238 5 low low JJ cord-022526-j9kg00qf 1238 6 - - HYPH cord-022526-j9kg00qf 1238 7 flow flow NN cord-022526-j9kg00qf 1238 8 ischemia ischemia NN cord-022526-j9kg00qf 1238 9 , , , cord-022526-j9kg00qf 1238 10 little little JJ cord-022526-j9kg00qf 1238 11 injury injury NN cord-022526-j9kg00qf 1238 12 is be VBZ cord-022526-j9kg00qf 1238 13 demonstrated demonstrate VBN cord-022526-j9kg00qf 1238 14 during during IN cord-022526-j9kg00qf 1238 15 3 3 CD cord-022526-j9kg00qf 1238 16 hours hour NNS cord-022526-j9kg00qf 1238 17 of of IN cord-022526-j9kg00qf 1238 18 ischemia ischemia NN cord-022526-j9kg00qf 1238 19 , , , cord-022526-j9kg00qf 1238 20 but but CC cord-022526-j9kg00qf 1238 21 remarkable remarkable JJ cord-022526-j9kg00qf 1238 22 injury injury NN cord-022526-j9kg00qf 1238 23 occurs occur VBZ cord-022526-j9kg00qf 1238 24 during during IN cord-022526-j9kg00qf 1238 25 1 1 CD cord-022526-j9kg00qf 1238 26 hour hour NN cord-022526-j9kg00qf 1238 27 of of IN cord-022526-j9kg00qf 1238 28 reperfusion reperfusion NN cord-022526-j9kg00qf 1238 29 . . . cord-022526-j9kg00qf 1239 1 [ [ -LRB- cord-022526-j9kg00qf 1239 2 83 83 CD cord-022526-j9kg00qf 1239 3 ] ] -RRB- cord-022526-j9kg00qf 1239 4 [ [ -LRB- cord-022526-j9kg00qf 1239 5 84 84 CD cord-022526-j9kg00qf 1239 6 ] ] -RRB- cord-022526-j9kg00qf 1240 1 [ [ -LRB- cord-022526-j9kg00qf 1240 2 85 85 CD cord-022526-j9kg00qf 1240 3 ] ] -RRB- cord-022526-j9kg00qf 1241 1 However however RB cord-022526-j9kg00qf 1241 2 , , , cord-022526-j9kg00qf 1241 3 a a DT cord-022526-j9kg00qf 1241 4 therapeutic therapeutic JJ cord-022526-j9kg00qf 1241 5 window window NN cord-022526-j9kg00qf 1241 6 may may MD cord-022526-j9kg00qf 1241 7 not not RB cord-022526-j9kg00qf 1241 8 exist exist VB cord-022526-j9kg00qf 1241 9 under under IN cord-022526-j9kg00qf 1241 10 conditions condition NNS cord-022526-j9kg00qf 1241 11 of of IN cord-022526-j9kg00qf 1241 12 strangulating strangulating JJ cord-022526-j9kg00qf 1241 13 obstruction obstruction NN cord-022526-j9kg00qf 1241 14 in in IN cord-022526-j9kg00qf 1241 15 which which WDT cord-022526-j9kg00qf 1241 16 severe severe JJ cord-022526-j9kg00qf 1241 17 injury injury NN cord-022526-j9kg00qf 1241 18 occurs occur VBZ cord-022526-j9kg00qf 1241 19 during during IN cord-022526-j9kg00qf 1241 20 ischemia ischemia NN cord-022526-j9kg00qf 1241 21 and and CC cord-022526-j9kg00qf 1241 22 minimal minimal JJ cord-022526-j9kg00qf 1241 23 injury injury NN cord-022526-j9kg00qf 1241 24 occurs occur VBZ cord-022526-j9kg00qf 1241 25 during during IN cord-022526-j9kg00qf 1241 26 reperfusion reperfusion NN cord-022526-j9kg00qf 1241 27 . . . cord-022526-j9kg00qf 1242 1 96 96 CD cord-022526-j9kg00qf 1243 1 This this DT cord-022526-j9kg00qf 1243 2 in in IN cord-022526-j9kg00qf 1243 3 turn turn NN cord-022526-j9kg00qf 1243 4 greatly greatly RB cord-022526-j9kg00qf 1243 5 reduces reduce VBZ cord-022526-j9kg00qf 1243 6 clinicians clinician NNS cord-022526-j9kg00qf 1243 7 ' ' POS cord-022526-j9kg00qf 1243 8 ability ability NN cord-022526-j9kg00qf 1243 9 to to TO cord-022526-j9kg00qf 1243 10 ameliorate ameliorate VB cord-022526-j9kg00qf 1243 11 ischemiareperfusion ischemiareperfusion NN cord-022526-j9kg00qf 1243 12 injury injury NN cord-022526-j9kg00qf 1243 13 with with IN cord-022526-j9kg00qf 1243 14 treatments treatment NNS cord-022526-j9kg00qf 1243 15 such such JJ cord-022526-j9kg00qf 1243 16 as as IN cord-022526-j9kg00qf 1243 17 antioxidants antioxidant NNS cord-022526-j9kg00qf 1243 18 at at IN cord-022526-j9kg00qf 1243 19 the the DT cord-022526-j9kg00qf 1243 20 time time NN cord-022526-j9kg00qf 1243 21 of of IN cord-022526-j9kg00qf 1243 22 reperfusion reperfusion NN cord-022526-j9kg00qf 1243 23 . . . cord-022526-j9kg00qf 1244 1 Mechanisms mechanism NNS cord-022526-j9kg00qf 1244 2 of of IN cord-022526-j9kg00qf 1244 3 gastric gastric JJ cord-022526-j9kg00qf 1244 4 repair repair NN cord-022526-j9kg00qf 1244 5 depend depend VBP cord-022526-j9kg00qf 1244 6 greatly greatly RB cord-022526-j9kg00qf 1244 7 on on IN cord-022526-j9kg00qf 1244 8 the the DT cord-022526-j9kg00qf 1244 9 extent extent NN cord-022526-j9kg00qf 1244 10 of of IN cord-022526-j9kg00qf 1244 11 injury injury NN cord-022526-j9kg00qf 1244 12 . . . cord-022526-j9kg00qf 1245 1 For for IN cord-022526-j9kg00qf 1245 2 instance instance NN cord-022526-j9kg00qf 1245 3 , , , cord-022526-j9kg00qf 1245 4 superficial superficial JJ cord-022526-j9kg00qf 1245 5 erosions erosion NNS cord-022526-j9kg00qf 1245 6 can can MD cord-022526-j9kg00qf 1245 7 be be VB cord-022526-j9kg00qf 1245 8 covered cover VBN cord-022526-j9kg00qf 1245 9 rapidly rapidly RB cord-022526-j9kg00qf 1245 10 by by IN cord-022526-j9kg00qf 1245 11 migration migration NN cord-022526-j9kg00qf 1245 12 of of IN cord-022526-j9kg00qf 1245 13 epithelium epithelium NN cord-022526-j9kg00qf 1245 14 adjacent adjacent JJ cord-022526-j9kg00qf 1245 15 to to IN cord-022526-j9kg00qf 1245 16 the the DT cord-022526-j9kg00qf 1245 17 wound wound NN cord-022526-j9kg00qf 1245 18 ; ; : cord-022526-j9kg00qf 1245 19 a a DT cord-022526-j9kg00qf 1245 20 process process NN cord-022526-j9kg00qf 1245 21 termed term VBN cord-022526-j9kg00qf 1245 22 epithelial epithelial JJ cord-022526-j9kg00qf 1245 23 restitution restitution NN cord-022526-j9kg00qf 1245 24 . . . cord-022526-j9kg00qf 1246 1 However however RB cord-022526-j9kg00qf 1246 2 , , , cord-022526-j9kg00qf 1246 3 ulceration ulceration NN cord-022526-j9kg00qf 1246 4 ( ( -LRB- cord-022526-j9kg00qf 1246 5 full full JJ cord-022526-j9kg00qf 1246 6 - - HYPH cord-022526-j9kg00qf 1246 7 thickness thickness NN cord-022526-j9kg00qf 1246 8 disruption disruption NN cord-022526-j9kg00qf 1246 9 of of IN cord-022526-j9kg00qf 1246 10 mucosa mucosa NN cord-022526-j9kg00qf 1246 11 and and CC cord-022526-j9kg00qf 1246 12 penetration penetration NN cord-022526-j9kg00qf 1246 13 of of IN cord-022526-j9kg00qf 1246 14 the the DT cord-022526-j9kg00qf 1246 15 muscularis muscularis JJ cord-022526-j9kg00qf 1246 16 mucosa mucosa NN cord-022526-j9kg00qf 1246 17 ) ) -RRB- cord-022526-j9kg00qf 1246 18 requires require VBZ cord-022526-j9kg00qf 1246 19 repair repair NN cord-022526-j9kg00qf 1246 20 of of IN cord-022526-j9kg00qf 1246 21 submucosal submucosal NN cord-022526-j9kg00qf 1246 22 vasculature vasculature NNP cord-022526-j9kg00qf 1246 23 and and CC cord-022526-j9kg00qf 1246 24 extracellular extracellular JJ cord-022526-j9kg00qf 1246 25 matrix matrix NN cord-022526-j9kg00qf 1246 26 . . . cord-022526-j9kg00qf 1247 1 The the DT cord-022526-j9kg00qf 1247 2 formation formation NN cord-022526-j9kg00qf 1247 3 of of IN cord-022526-j9kg00qf 1247 4 granulation granulation NN cord-022526-j9kg00qf 1247 5 tissue tissue NN cord-022526-j9kg00qf 1247 6 initiates initiate VBZ cord-022526-j9kg00qf 1247 7 repair repair NN cord-022526-j9kg00qf 1247 8 and and CC cord-022526-j9kg00qf 1247 9 supplies supply NNS cord-022526-j9kg00qf 1247 10 connective connective JJ cord-022526-j9kg00qf 1247 11 tissue tissue NN cord-022526-j9kg00qf 1247 12 elements element NNS cord-022526-j9kg00qf 1247 13 and and CC cord-022526-j9kg00qf 1247 14 microvasculature microvasculature NN cord-022526-j9kg00qf 1247 15 necessary necessary JJ cord-022526-j9kg00qf 1247 16 for for IN cord-022526-j9kg00qf 1247 17 mucosal mucosal JJ cord-022526-j9kg00qf 1247 18 reconstruction reconstruction NN cord-022526-j9kg00qf 1247 19 . . . cord-022526-j9kg00qf 1248 1 Connective connective JJ cord-022526-j9kg00qf 1248 2 tissue tissue NN cord-022526-j9kg00qf 1248 3 elements element NNS cord-022526-j9kg00qf 1248 4 include include VBP cord-022526-j9kg00qf 1248 5 proliferating proliferate VBG cord-022526-j9kg00qf 1248 6 fibroblasts fibroblast NNS cord-022526-j9kg00qf 1248 7 that that WDT cord-022526-j9kg00qf 1248 8 accompany accompany VBP cord-022526-j9kg00qf 1248 9 newly newly RB cord-022526-j9kg00qf 1248 10 produced produce VBN cord-022526-j9kg00qf 1248 11 capillaries capillary NNS cord-022526-j9kg00qf 1248 12 that that WDT cord-022526-j9kg00qf 1248 13 form form VBP cord-022526-j9kg00qf 1248 14 from from IN cord-022526-j9kg00qf 1248 15 proliferating proliferate VBG cord-022526-j9kg00qf 1248 16 endothelium endothelium NN cord-022526-j9kg00qf 1248 17 . . . cord-022526-j9kg00qf 1249 1 Recent recent JJ cord-022526-j9kg00qf 1249 2 studies study NNS cord-022526-j9kg00qf 1249 3 indicate indicate VBP cord-022526-j9kg00qf 1249 4 that that IN cord-022526-j9kg00qf 1249 5 nitric nitric JJ cord-022526-j9kg00qf 1249 6 oxide oxide NN cord-022526-j9kg00qf 1249 7 is be VBZ cord-022526-j9kg00qf 1249 8 critical critical JJ cord-022526-j9kg00qf 1249 9 to to IN cord-022526-j9kg00qf 1249 10 both both DT cord-022526-j9kg00qf 1249 11 processes process NNS cord-022526-j9kg00qf 1249 12 , , , cord-022526-j9kg00qf 1249 13 40 40 CD cord-022526-j9kg00qf 1249 14 , , , cord-022526-j9kg00qf 1249 15 97 97 CD cord-022526-j9kg00qf 1249 16 which which WDT cord-022526-j9kg00qf 1249 17 likely likely RB cord-022526-j9kg00qf 1249 18 explains explain VBZ cord-022526-j9kg00qf 1249 19 the the DT cord-022526-j9kg00qf 1249 20 reparative reparative JJ cord-022526-j9kg00qf 1249 21 properties property NNS cord-022526-j9kg00qf 1249 22 of of IN cord-022526-j9kg00qf 1249 23 nitric nitric JJ cord-022526-j9kg00qf 1249 24 oxide oxide NN cord-022526-j9kg00qf 1249 25 in in IN cord-022526-j9kg00qf 1249 26 the the DT cord-022526-j9kg00qf 1249 27 stomach stomach NN cord-022526-j9kg00qf 1249 28 . . . cord-022526-j9kg00qf 1250 1 98 98 CD cord-022526-j9kg00qf 1251 1 Once once IN cord-022526-j9kg00qf 1251 2 an an DT cord-022526-j9kg00qf 1251 3 adequate adequate JJ cord-022526-j9kg00qf 1251 4 granulation granulation NN cord-022526-j9kg00qf 1251 5 bed bed NN cord-022526-j9kg00qf 1251 6 has have VBZ cord-022526-j9kg00qf 1251 7 formed form VBN cord-022526-j9kg00qf 1251 8 , , , cord-022526-j9kg00qf 1251 9 newly newly RB cord-022526-j9kg00qf 1251 10 proliferated proliferate VBN cord-022526-j9kg00qf 1251 11 epithelium epithelium NN cord-022526-j9kg00qf 1251 12 at at IN cord-022526-j9kg00qf 1251 13 the the DT cord-022526-j9kg00qf 1251 14 edge edge NN cord-022526-j9kg00qf 1251 15 of of IN cord-022526-j9kg00qf 1251 16 the the DT cord-022526-j9kg00qf 1251 17 wound wound NN cord-022526-j9kg00qf 1251 18 begins begin VBZ cord-022526-j9kg00qf 1251 19 to to TO cord-022526-j9kg00qf 1251 20 migrate migrate VB cord-022526-j9kg00qf 1251 21 across across IN cord-022526-j9kg00qf 1251 22 the the DT cord-022526-j9kg00qf 1251 23 wound wound NN cord-022526-j9kg00qf 1251 24 . . . cord-022526-j9kg00qf 1252 1 In in IN cord-022526-j9kg00qf 1252 2 addition addition NN cord-022526-j9kg00qf 1252 3 , , , cord-022526-j9kg00qf 1252 4 gastric gastric JJ cord-022526-j9kg00qf 1252 5 glands gland NNS cord-022526-j9kg00qf 1252 6 at at IN cord-022526-j9kg00qf 1252 7 the the DT cord-022526-j9kg00qf 1252 8 base base NN cord-022526-j9kg00qf 1252 9 of of IN cord-022526-j9kg00qf 1252 10 the the DT cord-022526-j9kg00qf 1252 11 ulcer ulcer NN cord-022526-j9kg00qf 1252 12 begin begin VB cord-022526-j9kg00qf 1252 13 to to TO cord-022526-j9kg00qf 1252 14 bud bud VB cord-022526-j9kg00qf 1252 15 and and CC cord-022526-j9kg00qf 1252 16 migrate migrate VB cord-022526-j9kg00qf 1252 17 across across IN cord-022526-j9kg00qf 1252 18 the the DT cord-022526-j9kg00qf 1252 19 granulation granulation NN cord-022526-j9kg00qf 1252 20 bed bed NN cord-022526-j9kg00qf 1252 21 in in IN cord-022526-j9kg00qf 1252 22 a a DT cord-022526-j9kg00qf 1252 23 tubular tubular JJ cord-022526-j9kg00qf 1252 24 fashion fashion NN cord-022526-j9kg00qf 1252 25 . . . cord-022526-j9kg00qf 1253 1 99 99 CD cord-022526-j9kg00qf 1253 2 Repairing repair VBG cord-022526-j9kg00qf 1253 3 epithelium epithelium NN cord-022526-j9kg00qf 1253 4 expresses express VBZ cord-022526-j9kg00qf 1253 5 epidermal epidermal JJ cord-022526-j9kg00qf 1253 6 growth growth NN cord-022526-j9kg00qf 1253 7 factor factor NN cord-022526-j9kg00qf 1253 8 , , , cord-022526-j9kg00qf 1253 9 which which WDT cord-022526-j9kg00qf 1253 10 appears appear VBZ cord-022526-j9kg00qf 1253 11 to to TO cord-022526-j9kg00qf 1253 12 facilitate facilitate VB cord-022526-j9kg00qf 1253 13 these these DT cord-022526-j9kg00qf 1253 14 processes process NNS cord-022526-j9kg00qf 1253 15 . . . cord-022526-j9kg00qf 1254 1 100 100 CD cord-022526-j9kg00qf 1255 1 In in IN cord-022526-j9kg00qf 1255 2 addition addition NN cord-022526-j9kg00qf 1255 3 , , , cord-022526-j9kg00qf 1255 4 a a DT cord-022526-j9kg00qf 1255 5 mucoid mucoid JJ cord-022526-j9kg00qf 1255 6 cap cap NN cord-022526-j9kg00qf 1255 7 facilitates facilitate VBZ cord-022526-j9kg00qf 1255 8 these these DT cord-022526-j9kg00qf 1255 9 events event NNS cord-022526-j9kg00qf 1255 10 and and CC cord-022526-j9kg00qf 1255 11 retains retain VBZ cord-022526-j9kg00qf 1255 12 reparative reparative JJ cord-022526-j9kg00qf 1255 13 factors factor NNS cord-022526-j9kg00qf 1255 14 and and CC cord-022526-j9kg00qf 1255 15 serum serum NN cord-022526-j9kg00qf 1255 16 adjacent adjacent JJ cord-022526-j9kg00qf 1255 17 to to IN cord-022526-j9kg00qf 1255 18 the the DT cord-022526-j9kg00qf 1255 19 wound wound JJ cord-022526-j9kg00qf 1255 20 bed bed NN cord-022526-j9kg00qf 1255 21 . . . cord-022526-j9kg00qf 1256 1 51 51 CD cord-022526-j9kg00qf 1257 1 Once once IN cord-022526-j9kg00qf 1257 2 the the DT cord-022526-j9kg00qf 1257 3 ulcer ulcer NN cord-022526-j9kg00qf 1257 4 crater crater NN cord-022526-j9kg00qf 1257 5 has have VBZ cord-022526-j9kg00qf 1257 6 been be VBN cord-022526-j9kg00qf 1257 7 filled fill VBN cord-022526-j9kg00qf 1257 8 with with IN cord-022526-j9kg00qf 1257 9 granulation granulation NN cord-022526-j9kg00qf 1257 10 tissue tissue NN cord-022526-j9kg00qf 1257 11 and and CC cord-022526-j9kg00qf 1257 12 the the DT cord-022526-j9kg00qf 1257 13 wound wound NN cord-022526-j9kg00qf 1257 14 has have VBZ cord-022526-j9kg00qf 1257 15 been be VBN cord-022526-j9kg00qf 1257 16 reepithelialized reepithelialize VBN cord-022526-j9kg00qf 1257 17 , , , cord-022526-j9kg00qf 1257 18 the the DT cord-022526-j9kg00qf 1257 19 subepithelial subepithelial JJ cord-022526-j9kg00qf 1257 20 tissue tissue NN cord-022526-j9kg00qf 1257 21 remodels remodel NNS cord-022526-j9kg00qf 1257 22 by by IN cord-022526-j9kg00qf 1257 23 altering alter VBG cord-022526-j9kg00qf 1257 24 the the DT cord-022526-j9kg00qf 1257 25 type type NN cord-022526-j9kg00qf 1257 26 and and CC cord-022526-j9kg00qf 1257 27 amount amount NN cord-022526-j9kg00qf 1257 28 of of IN cord-022526-j9kg00qf 1257 29 collagen collagen NN cord-022526-j9kg00qf 1257 30 . . . cord-022526-j9kg00qf 1258 1 Despite despite IN cord-022526-j9kg00qf 1258 2 the the DT cord-022526-j9kg00qf 1258 3 remodeling remodeling NN cord-022526-j9kg00qf 1258 4 process process NN cord-022526-j9kg00qf 1258 5 , , , cord-022526-j9kg00qf 1258 6 ulcers ulcer NNS cord-022526-j9kg00qf 1258 7 tend tend VBP cord-022526-j9kg00qf 1258 8 to to TO cord-022526-j9kg00qf 1258 9 recur recur VB cord-022526-j9kg00qf 1258 10 at at IN cord-022526-j9kg00qf 1258 11 sites site NNS cord-022526-j9kg00qf 1258 12 of of IN cord-022526-j9kg00qf 1258 13 previous previous JJ cord-022526-j9kg00qf 1258 14 ulceration ulceration NN cord-022526-j9kg00qf 1258 15 , , , cord-022526-j9kg00qf 1258 16 and and CC cord-022526-j9kg00qf 1258 17 the the DT cord-022526-j9kg00qf 1258 18 concern concern NN cord-022526-j9kg00qf 1258 19 is be VBZ cord-022526-j9kg00qf 1258 20 that that IN cord-022526-j9kg00qf 1258 21 this this DT cord-022526-j9kg00qf 1258 22 remodeling remodeling NN cord-022526-j9kg00qf 1258 23 can can MD cord-022526-j9kg00qf 1258 24 result result VB cord-022526-j9kg00qf 1258 25 in in IN cord-022526-j9kg00qf 1258 26 excessive excessive JJ cord-022526-j9kg00qf 1258 27 deposition deposition NN cord-022526-j9kg00qf 1258 28 of of IN cord-022526-j9kg00qf 1258 29 collagen collagen NN cord-022526-j9kg00qf 1258 30 and and CC cord-022526-j9kg00qf 1258 31 fibrosis fibrosis NN cord-022526-j9kg00qf 1258 32 . . . cord-022526-j9kg00qf 1259 1 26 26 CD cord-022526-j9kg00qf 1259 2 Reparative reparative JJ cord-022526-j9kg00qf 1259 3 mechanisms mechanism NNS cord-022526-j9kg00qf 1259 4 are be VBP cord-022526-j9kg00qf 1259 5 similar similar JJ cord-022526-j9kg00qf 1259 6 in in IN cord-022526-j9kg00qf 1259 7 the the DT cord-022526-j9kg00qf 1259 8 intestine intestine NN cord-022526-j9kg00qf 1259 9 , , , cord-022526-j9kg00qf 1259 10 except except IN cord-022526-j9kg00qf 1259 11 that that DT cord-022526-j9kg00qf 1259 12 in in IN cord-022526-j9kg00qf 1259 13 the the DT cord-022526-j9kg00qf 1259 14 small small JJ cord-022526-j9kg00qf 1259 15 intestine intestine NN cord-022526-j9kg00qf 1259 16 , , , cord-022526-j9kg00qf 1259 17 mucosal mucosal JJ cord-022526-j9kg00qf 1259 18 villi villus NNS cord-022526-j9kg00qf 1259 19 contribute contribute VBP cord-022526-j9kg00qf 1259 20 to to IN cord-022526-j9kg00qf 1259 21 mucosal mucosal JJ cord-022526-j9kg00qf 1259 22 repair repair NN cord-022526-j9kg00qf 1259 23 . . . cord-022526-j9kg00qf 1260 1 Once once IN cord-022526-j9kg00qf 1260 2 intestinal intestinal JJ cord-022526-j9kg00qf 1260 3 epithelium epithelium NN cord-022526-j9kg00qf 1260 4 is be VBZ cord-022526-j9kg00qf 1260 5 disrupted disrupt VBN cord-022526-j9kg00qf 1260 6 , , , cord-022526-j9kg00qf 1260 7 two two CD cord-022526-j9kg00qf 1260 8 events event NNS cord-022526-j9kg00qf 1260 9 occur occur VBP cord-022526-j9kg00qf 1260 10 almost almost RB cord-022526-j9kg00qf 1260 11 immediately immediately RB cord-022526-j9kg00qf 1260 12 to to TO cord-022526-j9kg00qf 1260 13 reduce reduce VB cord-022526-j9kg00qf 1260 14 the the DT cord-022526-j9kg00qf 1260 15 size size NN cord-022526-j9kg00qf 1260 16 of of IN cord-022526-j9kg00qf 1260 17 the the DT cord-022526-j9kg00qf 1260 18 denuded denuded JJ cord-022526-j9kg00qf 1260 19 portion portion NN cord-022526-j9kg00qf 1260 20 of of IN cord-022526-j9kg00qf 1260 21 the the DT cord-022526-j9kg00qf 1260 22 villus villus NN cord-022526-j9kg00qf 1260 23 : : : cord-022526-j9kg00qf 1261 1 contraction contraction NN cord-022526-j9kg00qf 1261 2 of of IN cord-022526-j9kg00qf 1261 3 the the DT cord-022526-j9kg00qf 1261 4 villus villus NN cord-022526-j9kg00qf 1261 5 and and CC cord-022526-j9kg00qf 1261 6 epithelial epithelial JJ cord-022526-j9kg00qf 1261 7 restitution restitution NN cord-022526-j9kg00qf 1261 8 ( ( -LRB- cord-022526-j9kg00qf 1261 9 Figure figure NN cord-022526-j9kg00qf 1261 10 13 13 CD cord-022526-j9kg00qf 1261 11 .5 .5 CD cord-022526-j9kg00qf 1261 12 - - SYM cord-022526-j9kg00qf 1261 13 3 3 CD cord-022526-j9kg00qf 1261 14 ) ) -RRB- cord-022526-j9kg00qf 1261 15 . . . cord-022526-j9kg00qf 1262 1 For for IN cord-022526-j9kg00qf 1262 2 example example NN cord-022526-j9kg00qf 1262 3 , , , cord-022526-j9kg00qf 1262 4 in in IN cord-022526-j9kg00qf 1262 5 porcine porcine JJ cord-022526-j9kg00qf 1262 6 ileum ileum NN cord-022526-j9kg00qf 1262 7 subjected subject VBN cord-022526-j9kg00qf 1262 8 to to IN cord-022526-j9kg00qf 1262 9 2 2 CD cord-022526-j9kg00qf 1262 10 hours hour NNS cord-022526-j9kg00qf 1262 11 of of IN cord-022526-j9kg00qf 1262 12 ischemia ischemia NN cord-022526-j9kg00qf 1262 13 , , , cord-022526-j9kg00qf 1262 14 villi villi NNP cord-022526-j9kg00qf 1262 15 were be VBD cord-022526-j9kg00qf 1262 16 60 60 CD cord-022526-j9kg00qf 1262 17 % % NN cord-022526-j9kg00qf 1262 18 of of IN cord-022526-j9kg00qf 1262 19 their -PRON- PRP$ cord-022526-j9kg00qf 1262 20 former former JJ cord-022526-j9kg00qf 1262 21 height height NN cord-022526-j9kg00qf 1262 22 and and CC cord-022526-j9kg00qf 1262 23 50 50 CD cord-022526-j9kg00qf 1262 24 % % NN cord-022526-j9kg00qf 1262 25 of of IN cord-022526-j9kg00qf 1262 26 the the DT cord-022526-j9kg00qf 1262 27 denuded denude VBN cord-022526-j9kg00qf 1262 28 villous villous NNP cord-022526-j9kg00qf 1262 29 surface surface NN cord-022526-j9kg00qf 1262 30 area area NN cord-022526-j9kg00qf 1262 31 was be VBD cord-022526-j9kg00qf 1262 32 covered cover VBN cord-022526-j9kg00qf 1262 33 in in IN cord-022526-j9kg00qf 1262 34 flattened flattened JJ cord-022526-j9kg00qf 1262 35 epithelium epithelium NN cord-022526-j9kg00qf 1262 36 within within IN cord-022526-j9kg00qf 1262 37 6 6 CD cord-022526-j9kg00qf 1262 38 hours hour NNS cord-022526-j9kg00qf 1262 39 . . . cord-022526-j9kg00qf 1263 1 42 42 CD cord-022526-j9kg00qf 1263 2 Enteric enteric JJ cord-022526-j9kg00qf 1263 3 nerves nerve NNS cord-022526-j9kg00qf 1263 4 appear appear VBP cord-022526-j9kg00qf 1263 5 to to TO cord-022526-j9kg00qf 1263 6 regulate regulate VB cord-022526-j9kg00qf 1263 7 villous villous JJ cord-022526-j9kg00qf 1263 8 contraction contraction NN cord-022526-j9kg00qf 1263 9 , , , cord-022526-j9kg00qf 1263 10 because because IN cord-022526-j9kg00qf 1263 11 inhibition inhibition NN cord-022526-j9kg00qf 1263 12 of of IN cord-022526-j9kg00qf 1263 13 enteric enteric JJ cord-022526-j9kg00qf 1263 14 nerve nerve NN cord-022526-j9kg00qf 1263 15 conduction conduction NN cord-022526-j9kg00qf 1263 16 prevents prevent VBZ cord-022526-j9kg00qf 1263 17 villous villous NNP cord-022526-j9kg00qf 1263 18 shortening shorten VBG cord-022526-j9kg00qf 1263 19 following follow VBG cord-022526-j9kg00qf 1263 20 injury injury NN cord-022526-j9kg00qf 1263 21 . . . cord-022526-j9kg00qf 1264 1 The the DT cord-022526-j9kg00qf 1264 2 contractile contractile JJ cord-022526-j9kg00qf 1264 3 component component NN cord-022526-j9kg00qf 1264 4 of of IN cord-022526-j9kg00qf 1264 5 the the DT cord-022526-j9kg00qf 1264 6 villus villus NN cord-022526-j9kg00qf 1264 7 is be VBZ cord-022526-j9kg00qf 1264 8 a a DT cord-022526-j9kg00qf 1264 9 network network NN cord-022526-j9kg00qf 1264 10 of of IN cord-022526-j9kg00qf 1264 11 myofibroblasts myofibroblast NNS cord-022526-j9kg00qf 1264 12 distributed distribute VBN cord-022526-j9kg00qf 1264 13 throughout throughout IN cord-022526-j9kg00qf 1264 14 the the DT cord-022526-j9kg00qf 1264 15 lamina lamina JJ cord-022526-j9kg00qf 1264 16 propria propria NN cord-022526-j9kg00qf 1264 17 of of IN cord-022526-j9kg00qf 1264 18 the the DT cord-022526-j9kg00qf 1264 19 villus villus NN cord-022526-j9kg00qf 1264 20 and and CC cord-022526-j9kg00qf 1264 21 along along IN cord-022526-j9kg00qf 1264 22 the the DT cord-022526-j9kg00qf 1264 23 central central JJ cord-022526-j9kg00qf 1264 24 lacteal lacteal NN cord-022526-j9kg00qf 1264 25 . . . cord-022526-j9kg00qf 1265 1 Inhibition inhibition NN cord-022526-j9kg00qf 1265 2 of of IN cord-022526-j9kg00qf 1265 3 villous villous NNP cord-022526-j9kg00qf 1265 4 contraction contraction NN cord-022526-j9kg00qf 1265 5 results result NNS cord-022526-j9kg00qf 1265 6 in in IN cord-022526-j9kg00qf 1265 7 retarded retarded JJ cord-022526-j9kg00qf 1265 8 epithelial epithelial JJ cord-022526-j9kg00qf 1265 9 repair repair NN cord-022526-j9kg00qf 1265 10 because because IN cord-022526-j9kg00qf 1265 11 of of IN cord-022526-j9kg00qf 1265 12 the the DT cord-022526-j9kg00qf 1265 13 larger large JJR cord-022526-j9kg00qf 1265 14 denuded denude VBN cord-022526-j9kg00qf 1265 15 surface surface NN cord-022526-j9kg00qf 1265 16 that that WDT cord-022526-j9kg00qf 1265 17 remains remain VBZ cord-022526-j9kg00qf 1265 18 to to TO cord-022526-j9kg00qf 1265 19 be be VB cord-022526-j9kg00qf 1265 20 covered cover VBN cord-022526-j9kg00qf 1265 21 by by IN cord-022526-j9kg00qf 1265 22 migrating migrate VBG cord-022526-j9kg00qf 1265 23 epithelium epithelium NN cord-022526-j9kg00qf 1265 24 compared compare VBN cord-022526-j9kg00qf 1265 25 with with IN cord-022526-j9kg00qf 1265 26 similarly similarly RB cord-022526-j9kg00qf 1265 27 injured injure VBN cord-022526-j9kg00qf 1265 28 villi villus NNS cord-022526-j9kg00qf 1265 29 that that WDT cord-022526-j9kg00qf 1265 30 have have VBP cord-022526-j9kg00qf 1265 31 contracted contract VBN cord-022526-j9kg00qf 1265 32 . . . cord-022526-j9kg00qf 1266 1 43 43 CD cord-022526-j9kg00qf 1266 2 PGE PGE NNP cord-022526-j9kg00qf 1266 3 2 2 CD cord-022526-j9kg00qf 1266 4 also also RB cord-022526-j9kg00qf 1266 5 has have VBZ cord-022526-j9kg00qf 1266 6 been be VBN cord-022526-j9kg00qf 1266 7 implicated implicate VBN cord-022526-j9kg00qf 1266 8 in in IN cord-022526-j9kg00qf 1266 9 regulating regulate VBG cord-022526-j9kg00qf 1266 10 villous villous NNP cord-022526-j9kg00qf 1266 11 contraction contraction NN cord-022526-j9kg00qf 1266 12 , , , cord-022526-j9kg00qf 1266 13 because because IN cord-022526-j9kg00qf 1266 14 application application NN cord-022526-j9kg00qf 1266 15 of of IN cord-022526-j9kg00qf 1266 16 PGE PGE NNP cord-022526-j9kg00qf 1266 17 2 2 CD cord-022526-j9kg00qf 1266 18 resulted result VBD cord-022526-j9kg00qf 1266 19 in in IN cord-022526-j9kg00qf 1266 20 villous villous NN cord-022526-j9kg00qf 1266 21 contraction contraction NN cord-022526-j9kg00qf 1266 22 when when WRB cord-022526-j9kg00qf 1266 23 perfused perfuse VBN cord-022526-j9kg00qf 1266 24 through through IN cord-022526-j9kg00qf 1266 25 normal normal JJ cord-022526-j9kg00qf 1266 26 rat rat NN cord-022526-j9kg00qf 1266 27 ileum ileum NN cord-022526-j9kg00qf 1266 28 . . . cord-022526-j9kg00qf 1267 1 101 101 CD cord-022526-j9kg00qf 1268 1 As as IN cord-022526-j9kg00qf 1268 2 villi villi NNP cord-022526-j9kg00qf 1268 3 contract contract NN cord-022526-j9kg00qf 1268 4 , , , cord-022526-j9kg00qf 1268 5 assuming assume VBG cord-022526-j9kg00qf 1268 6 the the DT cord-022526-j9kg00qf 1268 7 basement basement NN cord-022526-j9kg00qf 1268 8 membrane membrane NN cord-022526-j9kg00qf 1268 9 is be VBZ cord-022526-j9kg00qf 1268 10 intact intact JJ cord-022526-j9kg00qf 1268 11 , , , cord-022526-j9kg00qf 1268 12 epithelium epithelium NN cord-022526-j9kg00qf 1268 13 from from IN cord-022526-j9kg00qf 1268 14 the the DT cord-022526-j9kg00qf 1268 15 margins margin NNS cord-022526-j9kg00qf 1268 16 of of IN cord-022526-j9kg00qf 1268 17 the the DT cord-022526-j9kg00qf 1268 18 wound wound NN cord-022526-j9kg00qf 1268 19 migrates migrate VBZ cord-022526-j9kg00qf 1268 20 centripetally centripetally RB cord-022526-j9kg00qf 1268 21 to to TO cord-022526-j9kg00qf 1268 22 resurface resurface VB cord-022526-j9kg00qf 1268 23 toward toward IN cord-022526-j9kg00qf 1268 24 the the DT cord-022526-j9kg00qf 1268 25 tip tip NN cord-022526-j9kg00qf 1268 26 of of IN cord-022526-j9kg00qf 1268 27 the the DT cord-022526-j9kg00qf 1268 28 villus villus NN cord-022526-j9kg00qf 1268 29 . . . cord-022526-j9kg00qf 1269 1 43 43 CD cord-022526-j9kg00qf 1270 1 The the DT cord-022526-j9kg00qf 1270 2 process process NN cord-022526-j9kg00qf 1270 3 of of IN cord-022526-j9kg00qf 1270 4 restitution restitution NN cord-022526-j9kg00qf 1270 5 is be VBZ cord-022526-j9kg00qf 1270 6 similar similar JJ cord-022526-j9kg00qf 1270 7 in in IN cord-022526-j9kg00qf 1270 8 denuded denuded JJ cord-022526-j9kg00qf 1270 9 colonic colonic JJ cord-022526-j9kg00qf 1270 10 mucosa mucosa NN cord-022526-j9kg00qf 1270 11 , , , cord-022526-j9kg00qf 1270 12 except except IN cord-022526-j9kg00qf 1270 13 that that IN cord-022526-j9kg00qf 1270 14 it -PRON- PRP cord-022526-j9kg00qf 1270 15 may may MD cord-022526-j9kg00qf 1270 16 proceed proceed VB cord-022526-j9kg00qf 1270 17 more more RBR cord-022526-j9kg00qf 1270 18 rapidly rapidly RB cord-022526-j9kg00qf 1270 19 because because IN cord-022526-j9kg00qf 1270 20 of of IN cord-022526-j9kg00qf 1270 21 the the DT cord-022526-j9kg00qf 1270 22 lack lack NN cord-022526-j9kg00qf 1270 23 of of IN cord-022526-j9kg00qf 1270 24 villi villi NN cord-022526-j9kg00qf 1270 25 . . . cord-022526-j9kg00qf 1271 1 41 41 CD cord-022526-j9kg00qf 1271 2 Epithelial epithelial JJ cord-022526-j9kg00qf 1271 3 restitution restitution NN cord-022526-j9kg00qf 1271 4 is be VBZ cord-022526-j9kg00qf 1271 5 solely solely RB cord-022526-j9kg00qf 1271 6 a a DT cord-022526-j9kg00qf 1271 7 migratory migratory JJ cord-022526-j9kg00qf 1271 8 event event NN cord-022526-j9kg00qf 1271 9 that that WDT cord-022526-j9kg00qf 1271 10 does do VBZ cord-022526-j9kg00qf 1271 11 not not RB cord-022526-j9kg00qf 1271 12 depend depend VB cord-022526-j9kg00qf 1271 13 on on IN cord-022526-j9kg00qf 1271 14 provision provision NN cord-022526-j9kg00qf 1271 15 of of IN cord-022526-j9kg00qf 1271 16 new new JJ cord-022526-j9kg00qf 1271 17 enterocytes enterocyte NNS cord-022526-j9kg00qf 1271 18 by by IN cord-022526-j9kg00qf 1271 19 proliferation proliferation NN cord-022526-j9kg00qf 1271 20 . . . cord-022526-j9kg00qf 1272 1 Cellular cellular JJ cord-022526-j9kg00qf 1272 2 migration migration NN cord-022526-j9kg00qf 1272 3 is be VBZ cord-022526-j9kg00qf 1272 4 initiated initiate VBN cord-022526-j9kg00qf 1272 5 by by IN cord-022526-j9kg00qf 1272 6 extension extension NN cord-022526-j9kg00qf 1272 7 of of IN cord-022526-j9kg00qf 1272 8 cellular cellular JJ cord-022526-j9kg00qf 1272 9 lamellipodia lamellipodia NNP cord-022526-j9kg00qf 1272 10 that that WDT cord-022526-j9kg00qf 1272 11 receive receive VBP cord-022526-j9kg00qf 1272 12 signals signal NNS cord-022526-j9kg00qf 1272 13 from from IN cord-022526-j9kg00qf 1272 14 the the DT cord-022526-j9kg00qf 1272 15 basement basement NN cord-022526-j9kg00qf 1272 16 membrane membrane NN cord-022526-j9kg00qf 1272 17 via via IN cord-022526-j9kg00qf 1272 18 integrins integrin NNS cord-022526-j9kg00qf 1272 19 . . . cord-022526-j9kg00qf 1273 1 Intracellular Intracellular NNP cord-022526-j9kg00qf 1273 2 signaling signal VBG cord-022526-j9kg00qf 1273 3 converges converge VBZ cord-022526-j9kg00qf 1273 4 on on IN cord-022526-j9kg00qf 1273 5 the the DT cord-022526-j9kg00qf 1273 6 actin actin NN cord-022526-j9kg00qf 1273 7 cytoskeleton cytoskeleton NN cord-022526-j9kg00qf 1273 8 , , , cord-022526-j9kg00qf 1273 9 which which WDT cord-022526-j9kg00qf 1273 10 is be VBZ cord-022526-j9kg00qf 1273 11 responsible responsible JJ cord-022526-j9kg00qf 1273 12 for for IN cord-022526-j9kg00qf 1273 13 movement movement NN cord-022526-j9kg00qf 1273 14 of of IN cord-022526-j9kg00qf 1273 15 lamellipodia lamellipodia NNP cord-022526-j9kg00qf 1273 16 . . . cord-022526-j9kg00qf 1274 1 Specific specific JJ cord-022526-j9kg00qf 1274 2 components component NNS cord-022526-j9kg00qf 1274 3 of of IN cord-022526-j9kg00qf 1274 4 the the DT cord-022526-j9kg00qf 1274 5 basement basement NN cord-022526-j9kg00qf 1274 6 membrane membrane NN cord-022526-j9kg00qf 1274 7 appear appear VBP cord-022526-j9kg00qf 1274 8 to to TO cord-022526-j9kg00qf 1274 9 be be VB cord-022526-j9kg00qf 1274 10 critical critical JJ cord-022526-j9kg00qf 1274 11 to to IN cord-022526-j9kg00qf 1274 12 the the DT cord-022526-j9kg00qf 1274 13 migratory migratory JJ cord-022526-j9kg00qf 1274 14 process process NN cord-022526-j9kg00qf 1274 15 . . . cord-022526-j9kg00qf 1275 1 For for IN cord-022526-j9kg00qf 1275 2 example example NN cord-022526-j9kg00qf 1275 3 , , , cord-022526-j9kg00qf 1275 4 application application NN cord-022526-j9kg00qf 1275 5 of of IN cord-022526-j9kg00qf 1275 6 antibodies antibody NNS cord-022526-j9kg00qf 1275 7 to to IN cord-022526-j9kg00qf 1275 8 collagen collagen NN cord-022526-j9kg00qf 1275 9 types type NNS cord-022526-j9kg00qf 1275 10 III III NNP cord-022526-j9kg00qf 1275 11 and and CC cord-022526-j9kg00qf 1275 12 IV IV NNP cord-022526-j9kg00qf 1275 13 , , , cord-022526-j9kg00qf 1275 14 which which WDT cord-022526-j9kg00qf 1275 15 are be VBP cord-022526-j9kg00qf 1275 16 important important JJ cord-022526-j9kg00qf 1275 17 components component NNS cord-022526-j9kg00qf 1275 18 of of IN cord-022526-j9kg00qf 1275 19 intestinal intestinal JJ cord-022526-j9kg00qf 1275 20 mucosal mucosal JJ cord-022526-j9kg00qf 1275 21 basement basement NN cord-022526-j9kg00qf 1275 22 membrane membrane NN cord-022526-j9kg00qf 1275 23 , , , cord-022526-j9kg00qf 1275 24 impeded impede VBD cord-022526-j9kg00qf 1275 25 epithelial epithelial JJ cord-022526-j9kg00qf 1275 26 restitution restitution NN cord-022526-j9kg00qf 1275 27 . . . cord-022526-j9kg00qf 1276 1 102 102 CD cord-022526-j9kg00qf 1276 2 , , , cord-022526-j9kg00qf 1276 3 103 103 CD cord-022526-j9kg00qf 1276 4 Other other JJ cord-022526-j9kg00qf 1276 5 elements element NNS cord-022526-j9kg00qf 1276 6 of of IN cord-022526-j9kg00qf 1276 7 the the DT cord-022526-j9kg00qf 1276 8 basement basement NN cord-022526-j9kg00qf 1276 9 membrane membrane NN cord-022526-j9kg00qf 1276 10 , , , cord-022526-j9kg00qf 1276 11 including include VBG cord-022526-j9kg00qf 1276 12 proteoglycans proteoglycan NNS cord-022526-j9kg00qf 1276 13 , , , cord-022526-j9kg00qf 1276 14 hyaluronic hyaluronic NN cord-022526-j9kg00qf 1276 15 acid acid NN cord-022526-j9kg00qf 1276 16 and and CC cord-022526-j9kg00qf 1276 17 noncollagenous noncollagenous JJ cord-022526-j9kg00qf 1276 18 proteins protein NNS cord-022526-j9kg00qf 1276 19 such such JJ cord-022526-j9kg00qf 1276 20 as as IN cord-022526-j9kg00qf 1276 21 fibronectin fibronectin NN cord-022526-j9kg00qf 1276 22 and and CC cord-022526-j9kg00qf 1276 23 laminin laminin NN cord-022526-j9kg00qf 1276 24 also also RB cord-022526-j9kg00qf 1276 25 may may MD cord-022526-j9kg00qf 1276 26 provide provide VB cord-022526-j9kg00qf 1276 27 important important JJ cord-022526-j9kg00qf 1276 28 signals signal NNS cord-022526-j9kg00qf 1276 29 . . . cord-022526-j9kg00qf 1277 1 104 104 CD cord-022526-j9kg00qf 1278 1 These these DT cord-022526-j9kg00qf 1278 2 subepithelial subepithelial JJ cord-022526-j9kg00qf 1278 3 matrix matrix NN cord-022526-j9kg00qf 1278 4 components component NNS cord-022526-j9kg00qf 1278 5 that that WDT cord-022526-j9kg00qf 1278 6 facilitate facilitate VBP cord-022526-j9kg00qf 1278 7 restitution restitution NN cord-022526-j9kg00qf 1278 8 may may MD cord-022526-j9kg00qf 1278 9 form form VB cord-022526-j9kg00qf 1278 10 the the DT cord-022526-j9kg00qf 1278 11 basis basis NN cord-022526-j9kg00qf 1278 12 for for IN cord-022526-j9kg00qf 1278 13 clinical clinical JJ cord-022526-j9kg00qf 1278 14 treatments treatment NNS cord-022526-j9kg00qf 1278 15 designed design VBN cord-022526-j9kg00qf 1278 16 to to TO cord-022526-j9kg00qf 1278 17 speed speed VB cord-022526-j9kg00qf 1278 18 up up RP cord-022526-j9kg00qf 1278 19 the the DT cord-022526-j9kg00qf 1278 20 repair repair NN cord-022526-j9kg00qf 1278 21 process process NN cord-022526-j9kg00qf 1278 22 , , , cord-022526-j9kg00qf 1278 23 analogous analogous JJ cord-022526-j9kg00qf 1278 24 to to IN cord-022526-j9kg00qf 1278 25 administration administration NN cord-022526-j9kg00qf 1278 26 of of IN cord-022526-j9kg00qf 1278 27 matrix matrix NN cord-022526-j9kg00qf 1278 28 components component NNS cord-022526-j9kg00qf 1278 29 to to IN cord-022526-j9kg00qf 1278 30 horses horse NNS cord-022526-j9kg00qf 1278 31 with with IN cord-022526-j9kg00qf 1278 32 articular articular JJ cord-022526-j9kg00qf 1278 33 cartilage cartilage NN cord-022526-j9kg00qf 1278 34 damage damage NN cord-022526-j9kg00qf 1278 35 . . . cord-022526-j9kg00qf 1279 1 Although although IN cord-022526-j9kg00qf 1279 2 epithelial epithelial JJ cord-022526-j9kg00qf 1279 3 restitution restitution NN cord-022526-j9kg00qf 1279 4 results result NNS cord-022526-j9kg00qf 1279 5 in in IN cord-022526-j9kg00qf 1279 6 gross gross JJ cord-022526-j9kg00qf 1279 7 closure closure NN cord-022526-j9kg00qf 1279 8 of of IN cord-022526-j9kg00qf 1279 9 previously previously RB cord-022526-j9kg00qf 1279 10 denuded denude VBN cord-022526-j9kg00qf 1279 11 regions region NNS cord-022526-j9kg00qf 1279 12 of of IN cord-022526-j9kg00qf 1279 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1279 14 mucosa mucosa NN cord-022526-j9kg00qf 1279 15 , , , cord-022526-j9kg00qf 1279 16 closure closure NN cord-022526-j9kg00qf 1279 17 of of IN cord-022526-j9kg00qf 1279 18 interepithelial interepithelial JJ cord-022526-j9kg00qf 1279 19 spaces space NNS cord-022526-j9kg00qf 1279 20 ultimately ultimately RB cord-022526-j9kg00qf 1279 21 is be VBZ cord-022526-j9kg00qf 1279 22 required require VBN cord-022526-j9kg00qf 1279 23 to to TO cord-022526-j9kg00qf 1279 24 restore restore VB cord-022526-j9kg00qf 1279 25 normal normal JJ cord-022526-j9kg00qf 1279 26 epithelial epithelial JJ cord-022526-j9kg00qf 1279 27 barrier barrier NN cord-022526-j9kg00qf 1279 28 resistance resistance NN cord-022526-j9kg00qf 1279 29 . . . cord-022526-j9kg00qf 1280 1 Because because IN cord-022526-j9kg00qf 1280 2 the the DT cord-022526-j9kg00qf 1280 3 tight tight JJ cord-022526-j9kg00qf 1280 4 junction junction NN cord-022526-j9kg00qf 1280 5 is be VBZ cord-022526-j9kg00qf 1280 6 principally principally RB cord-022526-j9kg00qf 1280 7 responsible responsible JJ cord-022526-j9kg00qf 1280 8 for for IN cord-022526-j9kg00qf 1280 9 regulating regulate VBG cord-022526-j9kg00qf 1280 10 the the DT cord-022526-j9kg00qf 1280 11 permeability permeability NN cord-022526-j9kg00qf 1280 12 of of IN cord-022526-j9kg00qf 1280 13 the the DT cord-022526-j9kg00qf 1280 14 interepithelial interepithelial JJ cord-022526-j9kg00qf 1280 15 space space NN cord-022526-j9kg00qf 1280 16 , , , cord-022526-j9kg00qf 1280 17 repair repair NN cord-022526-j9kg00qf 1280 18 and and CC cord-022526-j9kg00qf 1280 19 closure closure NN cord-022526-j9kg00qf 1280 20 of of IN cord-022526-j9kg00qf 1280 21 this this DT cord-022526-j9kg00qf 1280 22 structure structure NN cord-022526-j9kg00qf 1280 23 likely likely RB cord-022526-j9kg00qf 1280 24 is be VBZ cord-022526-j9kg00qf 1280 25 critical critical JJ cord-022526-j9kg00qf 1280 26 to to TO cord-022526-j9kg00qf 1280 27 restore restore VB cord-022526-j9kg00qf 1280 28 intestinal intestinal JJ cord-022526-j9kg00qf 1280 29 barrier barrier NN cord-022526-j9kg00qf 1280 30 function function NN cord-022526-j9kg00qf 1280 31 . . . cord-022526-j9kg00qf 1281 1 Recent recent JJ cord-022526-j9kg00qf 1281 2 research research NN cord-022526-j9kg00qf 1281 3 indicates indicate VBZ cord-022526-j9kg00qf 1281 4 that that IN cord-022526-j9kg00qf 1281 5 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1281 6 play play VBP cord-022526-j9kg00qf 1281 7 a a DT cord-022526-j9kg00qf 1281 8 vital vital JJ cord-022526-j9kg00qf 1281 9 role role NN cord-022526-j9kg00qf 1281 10 in in IN cord-022526-j9kg00qf 1281 11 recovery recovery NN cord-022526-j9kg00qf 1281 12 of of IN cord-022526-j9kg00qf 1281 13 tight tight JJ cord-022526-j9kg00qf 1281 14 junction junction NN cord-022526-j9kg00qf 1281 15 resistance resistance NN cord-022526-j9kg00qf 1281 16 , , , cord-022526-j9kg00qf 1281 17 105 105 CD cord-022526-j9kg00qf 1281 18 indicating indicate VBG cord-022526-j9kg00qf 1281 19 that that IN cord-022526-j9kg00qf 1281 20 administration administration NN cord-022526-j9kg00qf 1281 21 of of IN cord-022526-j9kg00qf 1281 22 nonselective nonselective JJ cord-022526-j9kg00qf 1281 23 COX COX NNP cord-022526-j9kg00qf 1281 24 inhibitors inhibitor NNS cord-022526-j9kg00qf 1281 25 to to IN cord-022526-j9kg00qf 1281 26 horses horse NNS cord-022526-j9kg00qf 1281 27 with with IN cord-022526-j9kg00qf 1281 28 colic colic NN cord-022526-j9kg00qf 1281 29 , , , cord-022526-j9kg00qf 1281 30 particularly particularly RB cord-022526-j9kg00qf 1281 31 those those DT cord-022526-j9kg00qf 1281 32 recovering recover VBG cord-022526-j9kg00qf 1281 33 from from IN cord-022526-j9kg00qf 1281 34 strangulating strangulating JJ cord-022526-j9kg00qf 1281 35 obstruction obstruction NN cord-022526-j9kg00qf 1281 36 , , , cord-022526-j9kg00qf 1281 37 may may MD cord-022526-j9kg00qf 1281 38 be be VB cord-022526-j9kg00qf 1281 39 deleterious deleterious JJ cord-022526-j9kg00qf 1281 40 . . . cord-022526-j9kg00qf 1282 1 Therefore therefore RB cord-022526-j9kg00qf 1282 2 judicious judicious JJ cord-022526-j9kg00qf 1282 3 use use NN cord-022526-j9kg00qf 1282 4 of of IN cord-022526-j9kg00qf 1282 5 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 1282 6 is be VBZ cord-022526-j9kg00qf 1282 7 appropriate appropriate JJ cord-022526-j9kg00qf 1282 8 until until IN cord-022526-j9kg00qf 1282 9 more more RBR cord-022526-j9kg00qf 1282 10 selective selective JJ cord-022526-j9kg00qf 1282 11 drugs drug NNS cord-022526-j9kg00qf 1282 12 that that WDT cord-022526-j9kg00qf 1282 13 allow allow VBP cord-022526-j9kg00qf 1282 14 continued continued JJ cord-022526-j9kg00qf 1282 15 production production NN cord-022526-j9kg00qf 1282 16 of of IN cord-022526-j9kg00qf 1282 17 reparative reparative JJ cord-022526-j9kg00qf 1282 18 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1282 19 are be VBP cord-022526-j9kg00qf 1282 20 available available JJ cord-022526-j9kg00qf 1282 21 for for IN cord-022526-j9kg00qf 1282 22 use use NN cord-022526-j9kg00qf 1282 23 in in IN cord-022526-j9kg00qf 1282 24 horse horse NN cord-022526-j9kg00qf 1282 25 . . . cord-022526-j9kg00qf 1283 1 56 56 CD cord-022526-j9kg00qf 1284 1 After after IN cord-022526-j9kg00qf 1284 2 restoration restoration NN cord-022526-j9kg00qf 1284 3 of of IN cord-022526-j9kg00qf 1284 4 the the DT cord-022526-j9kg00qf 1284 5 epithelial epithelial JJ cord-022526-j9kg00qf 1284 6 barrier barrier NN cord-022526-j9kg00qf 1284 7 , , , cord-022526-j9kg00qf 1284 8 the the DT cord-022526-j9kg00qf 1284 9 epithelium epithelium NN cord-022526-j9kg00qf 1284 10 must must MD cord-022526-j9kg00qf 1284 11 reestablish reestablish VB cord-022526-j9kg00qf 1284 12 normal normal JJ cord-022526-j9kg00qf 1284 13 mucosal mucosal JJ cord-022526-j9kg00qf 1284 14 architecture architecture NN cord-022526-j9kg00qf 1284 15 to to TO cord-022526-j9kg00qf 1284 16 allow allow VB cord-022526-j9kg00qf 1284 17 normal normal JJ cord-022526-j9kg00qf 1284 18 gut gut NN cord-022526-j9kg00qf 1284 19 absorptive absorptive JJ cord-022526-j9kg00qf 1284 20 and and CC cord-022526-j9kg00qf 1284 21 digestive digestive JJ cord-022526-j9kg00qf 1284 22 function function NN cord-022526-j9kg00qf 1284 23 . . . cord-022526-j9kg00qf 1285 1 In in IN cord-022526-j9kg00qf 1285 2 porcine porcine JJ cord-022526-j9kg00qf 1285 3 ileum ileum NN cord-022526-j9kg00qf 1285 4 subjected subject VBN cord-022526-j9kg00qf 1285 5 to to IN cord-022526-j9kg00qf 1285 6 2 2 CD cord-022526-j9kg00qf 1285 7 hours hour NNS cord-022526-j9kg00qf 1285 8 of of IN cord-022526-j9kg00qf 1285 9 ischemia ischemia NN cord-022526-j9kg00qf 1285 10 , , , cord-022526-j9kg00qf 1285 11 the the DT cord-022526-j9kg00qf 1285 12 epithelial epithelial JJ cord-022526-j9kg00qf 1285 13 barrier barrier NN cord-022526-j9kg00qf 1285 14 was be VBD cord-022526-j9kg00qf 1285 15 restored restore VBN cord-022526-j9kg00qf 1285 16 within within IN cord-022526-j9kg00qf 1285 17 18 18 CD cord-022526-j9kg00qf 1285 18 hours hour NNS cord-022526-j9kg00qf 1285 19 , , , cord-022526-j9kg00qf 1285 20 but but CC cord-022526-j9kg00qf 1285 21 villi villi NNP cord-022526-j9kg00qf 1285 22 were be VBD cord-022526-j9kg00qf 1285 23 contracted contract VBN cord-022526-j9kg00qf 1285 24 and and CC cord-022526-j9kg00qf 1285 25 covered cover VBN cord-022526-j9kg00qf 1285 26 in in IN cord-022526-j9kg00qf 1285 27 epithelium epithelium NN cord-022526-j9kg00qf 1285 28 with with IN cord-022526-j9kg00qf 1285 29 a a DT cord-022526-j9kg00qf 1285 30 squamous squamous JJ cord-022526-j9kg00qf 1285 31 appearance appearance NN cord-022526-j9kg00qf 1285 32 . . . cord-022526-j9kg00qf 1286 1 Restoration restoration NN cord-022526-j9kg00qf 1286 2 of of IN cord-022526-j9kg00qf 1286 3 normal normal JJ cord-022526-j9kg00qf 1286 4 villous villous NN cord-022526-j9kg00qf 1286 5 architecture architecture NN cord-022526-j9kg00qf 1286 6 required require VBD cord-022526-j9kg00qf 1286 7 another another DT cord-022526-j9kg00qf 1286 8 4 4 CD cord-022526-j9kg00qf 1286 9 days day NNS cord-022526-j9kg00qf 1286 10 . . . cord-022526-j9kg00qf 1287 1 42 42 CD cord-022526-j9kg00qf 1287 2 Newly newly RB cord-022526-j9kg00qf 1287 3 proliferated proliferate VBN cord-022526-j9kg00qf 1287 4 crypt crypt JJ cord-022526-j9kg00qf 1287 5 epithelium epithelium NN cord-022526-j9kg00qf 1287 6 replaces replace VBZ cord-022526-j9kg00qf 1287 7 the the DT cord-022526-j9kg00qf 1287 8 flattened flatten VBN cord-022526-j9kg00qf 1287 9 villous villous JJ cord-022526-j9kg00qf 1287 10 epithelium epithelium NN cord-022526-j9kg00qf 1287 11 that that WDT cord-022526-j9kg00qf 1287 12 characterizes characterize VBZ cord-022526-j9kg00qf 1287 13 restitution restitution NN cord-022526-j9kg00qf 1287 14 . . . cord-022526-j9kg00qf 1288 1 Under under IN cord-022526-j9kg00qf 1288 2 normal normal JJ cord-022526-j9kg00qf 1288 3 circumstances circumstance NNS cord-022526-j9kg00qf 1288 4 the the DT cord-022526-j9kg00qf 1288 5 dividing divide VBG cord-022526-j9kg00qf 1288 6 stem stem NN cord-022526-j9kg00qf 1288 7 cells cell NNS cord-022526-j9kg00qf 1288 8 , , , cord-022526-j9kg00qf 1288 9 of of IN cord-022526-j9kg00qf 1288 10 which which WDT cord-022526-j9kg00qf 1288 11 the the DT cord-022526-j9kg00qf 1288 12 base base NN cord-022526-j9kg00qf 1288 13 of of IN cord-022526-j9kg00qf 1288 14 each each DT cord-022526-j9kg00qf 1288 15 mucosal mucosal JJ cord-022526-j9kg00qf 1288 16 crypt crypt NN cord-022526-j9kg00qf 1288 17 has have VBZ cord-022526-j9kg00qf 1288 18 approximately approximately RB cord-022526-j9kg00qf 1288 19 four four CD cord-022526-j9kg00qf 1288 20 , , , cord-022526-j9kg00qf 1288 21 form form VB cord-022526-j9kg00qf 1288 22 new new JJ cord-022526-j9kg00qf 1288 23 enterocytes enterocyte NNS cord-022526-j9kg00qf 1288 24 . . . cord-022526-j9kg00qf 1289 1 Newly newly RB cord-022526-j9kg00qf 1289 2 divided divide VBN cord-022526-j9kg00qf 1289 3 enterocytes enterocyte NNS cord-022526-j9kg00qf 1289 4 migrate migrate VBP cord-022526-j9kg00qf 1289 5 from from IN cord-022526-j9kg00qf 1289 6 the the DT cord-022526-j9kg00qf 1289 7 crypt crypt NN cord-022526-j9kg00qf 1289 8 onto onto IN cord-022526-j9kg00qf 1289 9 the the DT cord-022526-j9kg00qf 1289 10 villus villus NN cord-022526-j9kg00qf 1289 11 . . . cord-022526-j9kg00qf 1290 1 106 106 CD cord-022526-j9kg00qf 1291 1 During during IN cord-022526-j9kg00qf 1291 2 migration migration NN cord-022526-j9kg00qf 1291 3 , , , cord-022526-j9kg00qf 1291 4 enterocytes enterocyte NNS cord-022526-j9kg00qf 1291 5 differentiate differentiate VBP cord-022526-j9kg00qf 1291 6 and and CC cord-022526-j9kg00qf 1291 7 acquire acquire VBP cord-022526-j9kg00qf 1291 8 specific specific JJ cord-022526-j9kg00qf 1291 9 absorptive absorptive JJ cord-022526-j9kg00qf 1291 10 and and CC cord-022526-j9kg00qf 1291 11 digestive digestive JJ cord-022526-j9kg00qf 1291 12 functions function NNS cord-022526-j9kg00qf 1291 13 . . . cord-022526-j9kg00qf 1292 1 Fully fully RB cord-022526-j9kg00qf 1292 2 differentiated differentiate VBN cord-022526-j9kg00qf 1292 3 enterocytes enterocyte NNS cord-022526-j9kg00qf 1292 4 reside reside VBP cord-022526-j9kg00qf 1292 5 on on IN cord-022526-j9kg00qf 1292 6 the the DT cord-022526-j9kg00qf 1292 7 upper upper JJ cord-022526-j9kg00qf 1292 8 third third NN cord-022526-j9kg00qf 1292 9 of of IN cord-022526-j9kg00qf 1292 10 the the DT cord-022526-j9kg00qf 1292 11 villus villus NN cord-022526-j9kg00qf 1292 12 for for IN cord-022526-j9kg00qf 1292 13 2 2 CD cord-022526-j9kg00qf 1292 14 to to TO cord-022526-j9kg00qf 1292 15 3 3 CD cord-022526-j9kg00qf 1292 16 days day NNS cord-022526-j9kg00qf 1292 17 and and CC cord-022526-j9kg00qf 1292 18 then then RB cord-022526-j9kg00qf 1292 19 are be VBP cord-022526-j9kg00qf 1292 20 sloughed slough VBN cord-022526-j9kg00qf 1292 21 into into IN cord-022526-j9kg00qf 1292 22 the the DT cord-022526-j9kg00qf 1292 23 intestinal intestinal JJ cord-022526-j9kg00qf 1292 24 lumen lumen NN cord-022526-j9kg00qf 1292 25 . . . cord-022526-j9kg00qf 1293 1 107 107 CD cord-022526-j9kg00qf 1294 1 This this DT cord-022526-j9kg00qf 1294 2 process process NN cord-022526-j9kg00qf 1294 3 accelerates accelerate VBZ cord-022526-j9kg00qf 1294 4 during during IN cord-022526-j9kg00qf 1294 5 mucosal mucosal JJ cord-022526-j9kg00qf 1294 6 repair repair NN cord-022526-j9kg00qf 1294 7 and and CC cord-022526-j9kg00qf 1294 8 requires require VBZ cord-022526-j9kg00qf 1294 9 increased increase VBN cord-022526-j9kg00qf 1294 10 proliferative proliferative JJ cord-022526-j9kg00qf 1294 11 rates rate NNS cord-022526-j9kg00qf 1294 12 . . . cord-022526-j9kg00qf 1295 1 A a DT cord-022526-j9kg00qf 1295 2 variety variety NN cord-022526-j9kg00qf 1295 3 of of IN cord-022526-j9kg00qf 1295 4 locally locally RB cord-022526-j9kg00qf 1295 5 available available JJ cord-022526-j9kg00qf 1295 6 gut gut NN cord-022526-j9kg00qf 1295 7 - - HYPH cord-022526-j9kg00qf 1295 8 derived derive VBN cord-022526-j9kg00qf 1295 9 factors factor NNS cord-022526-j9kg00qf 1295 10 , , , cord-022526-j9kg00qf 1295 11 including include VBG cord-022526-j9kg00qf 1295 12 luminal luminal JJ cord-022526-j9kg00qf 1295 13 nutrients nutrient NNS cord-022526-j9kg00qf 1295 14 , , , cord-022526-j9kg00qf 1295 15 polyamines polyamine NNS cord-022526-j9kg00qf 1295 16 , , , cord-022526-j9kg00qf 1295 17 and and CC cord-022526-j9kg00qf 1295 18 growth growth NN cord-022526-j9kg00qf 1295 19 factors factor NNS cord-022526-j9kg00qf 1295 20 , , , cord-022526-j9kg00qf 1295 21 may may MD cord-022526-j9kg00qf 1295 22 stimulate stimulate VB cord-022526-j9kg00qf 1295 23 increased increase VBN cord-022526-j9kg00qf 1295 24 proliferation proliferation NN cord-022526-j9kg00qf 1295 25 within within IN cord-022526-j9kg00qf 1295 26 12 12 CD cord-022526-j9kg00qf 1295 27 to to TO cord-022526-j9kg00qf 1295 28 18 18 CD cord-022526-j9kg00qf 1295 29 hours hour NNS cord-022526-j9kg00qf 1295 30 . . . cord-022526-j9kg00qf 1296 1 42 42 CD cord-022526-j9kg00qf 1297 1 The the DT cord-022526-j9kg00qf 1297 2 return return NN cord-022526-j9kg00qf 1297 3 of of IN cord-022526-j9kg00qf 1297 4 the the DT cord-022526-j9kg00qf 1297 5 normal normal JJ cord-022526-j9kg00qf 1297 6 leaflike leaflike JJ cord-022526-j9kg00qf 1297 7 shape shape NN cord-022526-j9kg00qf 1297 8 of of IN cord-022526-j9kg00qf 1297 9 the the DT cord-022526-j9kg00qf 1297 10 villus villus NN cord-022526-j9kg00qf 1297 11 occurs occur VBZ cord-022526-j9kg00qf 1297 12 following follow VBG cord-022526-j9kg00qf 1297 13 the the DT cord-022526-j9kg00qf 1297 14 appearance appearance NN cord-022526-j9kg00qf 1297 15 of of IN cord-022526-j9kg00qf 1297 16 normal normal JJ cord-022526-j9kg00qf 1297 17 columnar columnar JJ cord-022526-j9kg00qf 1297 18 epithelium epithelium NN cord-022526-j9kg00qf 1297 19 . . . cord-022526-j9kg00qf 1298 1 Although although IN cord-022526-j9kg00qf 1298 2 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1298 3 have have VBP cord-022526-j9kg00qf 1298 4 been be VBN cord-022526-j9kg00qf 1298 5 implicated implicate VBN cord-022526-j9kg00qf 1298 6 in in IN cord-022526-j9kg00qf 1298 7 mucosal mucosal JJ cord-022526-j9kg00qf 1298 8 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 1298 9 function function NN cord-022526-j9kg00qf 1298 10 , , , cord-022526-j9kg00qf 1298 11 few few JJ cord-022526-j9kg00qf 1298 12 studies study NNS cord-022526-j9kg00qf 1298 13 have have VBP cord-022526-j9kg00qf 1298 14 assessed assess VBN cord-022526-j9kg00qf 1298 15 their -PRON- PRP$ cord-022526-j9kg00qf 1298 16 importance importance NN cord-022526-j9kg00qf 1298 17 in in IN cord-022526-j9kg00qf 1298 18 mucosal mucosal JJ cord-022526-j9kg00qf 1298 19 repair repair NN cord-022526-j9kg00qf 1298 20 . . . cord-022526-j9kg00qf 1299 1 One one CD cord-022526-j9kg00qf 1299 2 study study NN cord-022526-j9kg00qf 1299 3 implicated implicate VBD cord-022526-j9kg00qf 1299 4 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1299 5 in in IN cord-022526-j9kg00qf 1299 6 growth growth NN cord-022526-j9kg00qf 1299 7 factor factor NN cord-022526-j9kg00qf 1299 8 - - HYPH cord-022526-j9kg00qf 1299 9 stimulated stimulate VBN cord-022526-j9kg00qf 1299 10 restitution restitution NN cord-022526-j9kg00qf 1299 11 , , , cord-022526-j9kg00qf 1299 12 108 108 CD cord-022526-j9kg00qf 1299 13 but but CC cord-022526-j9kg00qf 1299 14 a a DT cord-022526-j9kg00qf 1299 15 more more RBR cord-022526-j9kg00qf 1299 16 prominent prominent JJ cord-022526-j9kg00qf 1299 17 role role NN cord-022526-j9kg00qf 1299 18 of of IN cord-022526-j9kg00qf 1299 19 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1299 20 in in IN cord-022526-j9kg00qf 1299 21 mucosal mucosal JJ cord-022526-j9kg00qf 1299 22 repair repair NN cord-022526-j9kg00qf 1299 23 is be VBZ cord-022526-j9kg00qf 1299 24 their -PRON- PRP$ cord-022526-j9kg00qf 1299 25 ability ability NN cord-022526-j9kg00qf 1299 26 to to TO cord-022526-j9kg00qf 1299 27 close close VB cord-022526-j9kg00qf 1299 28 interepithelial interepithelial JJ cord-022526-j9kg00qf 1299 29 tight tight JJ cord-022526-j9kg00qf 1299 30 junctions junction NNS cord-022526-j9kg00qf 1299 31 . . . cord-022526-j9kg00qf 1300 1 105 105 CD cord-022526-j9kg00qf 1300 2 , , , cord-022526-j9kg00qf 1300 3 109 109 CD cord-022526-j9kg00qf 1300 4 , , , cord-022526-j9kg00qf 1300 5 110 110 CD cord-022526-j9kg00qf 1301 1 For for IN cord-022526-j9kg00qf 1301 2 instance instance NN cord-022526-j9kg00qf 1301 3 , , , cord-022526-j9kg00qf 1301 4 ischemic ischemic JJ cord-022526-j9kg00qf 1301 5 - - HYPH cord-022526-j9kg00qf 1301 6 injured injure VBN cord-022526-j9kg00qf 1301 7 small small JJ cord-022526-j9kg00qf 1301 8 intestine intestine NN cord-022526-j9kg00qf 1301 9 rapidly rapidly RB cord-022526-j9kg00qf 1301 10 recovers recover VBZ cord-022526-j9kg00qf 1301 11 barrier barrier NN cord-022526-j9kg00qf 1301 12 function function NN cord-022526-j9kg00qf 1301 13 ( ( -LRB- cord-022526-j9kg00qf 1301 14 as as IN cord-022526-j9kg00qf 1301 15 measured measure VBN cord-022526-j9kg00qf 1301 16 in in IN cord-022526-j9kg00qf 1301 17 vitro vitro FW cord-022526-j9kg00qf 1301 18 as as IN cord-022526-j9kg00qf 1301 19 transepithelial transepithelial JJ cord-022526-j9kg00qf 1301 20 resistance resistance NN cord-022526-j9kg00qf 1301 21 ) ) -RRB- cord-022526-j9kg00qf 1301 22 in in IN cord-022526-j9kg00qf 1301 23 the the DT cord-022526-j9kg00qf 1301 24 presence presence NN cord-022526-j9kg00qf 1301 25 of of IN cord-022526-j9kg00qf 1301 26 PGI PGI NNP cord-022526-j9kg00qf 1301 27 2 2 CD cord-022526-j9kg00qf 1301 28 and and CC cord-022526-j9kg00qf 1301 29 PGE PGE NNP cord-022526-j9kg00qf 1301 30 2 2 CD cord-022526-j9kg00qf 1301 31 , , , cord-022526-j9kg00qf 1301 32 despite despite IN cord-022526-j9kg00qf 1301 33 the the DT cord-022526-j9kg00qf 1301 34 fact fact NN cord-022526-j9kg00qf 1301 35 that that IN cord-022526-j9kg00qf 1301 36 these these DT cord-022526-j9kg00qf 1301 37 prostanoids prostanoid NNS cord-022526-j9kg00qf 1301 38 had have VBD cord-022526-j9kg00qf 1301 39 little little JJ cord-022526-j9kg00qf 1301 40 effect effect NN cord-022526-j9kg00qf 1301 41 on on IN cord-022526-j9kg00qf 1301 42 villous villous JJ cord-022526-j9kg00qf 1301 43 contraction contraction NN cord-022526-j9kg00qf 1301 44 and and CC cord-022526-j9kg00qf 1301 45 epithelial epithelial JJ cord-022526-j9kg00qf 1301 46 restitution restitution NN cord-022526-j9kg00qf 1301 47 . . . cord-022526-j9kg00qf 1302 1 However however RB cord-022526-j9kg00qf 1302 2 , , , cord-022526-j9kg00qf 1302 3 electron electron NN cord-022526-j9kg00qf 1302 4 microscopic microscopic JJ cord-022526-j9kg00qf 1302 5 examination examination NN cord-022526-j9kg00qf 1302 6 of of IN cord-022526-j9kg00qf 1302 7 tissues tissue NNS cord-022526-j9kg00qf 1302 8 reveals reveal VBZ cord-022526-j9kg00qf 1302 9 dilation dilation NN cord-022526-j9kg00qf 1302 10 of of IN cord-022526-j9kg00qf 1302 11 tight tight JJ cord-022526-j9kg00qf 1302 12 junctions junction NNS cord-022526-j9kg00qf 1302 13 in in IN cord-022526-j9kg00qf 1302 14 tissues tissue NNS cord-022526-j9kg00qf 1302 15 treated treat VBN cord-022526-j9kg00qf 1302 16 with with IN cord-022526-j9kg00qf 1302 17 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 1302 18 , , , cord-022526-j9kg00qf 1302 19 110 110 CD cord-022526-j9kg00qf 1302 20 whereas whereas IN cord-022526-j9kg00qf 1302 21 those those DT cord-022526-j9kg00qf 1302 22 additionally additionally RB cord-022526-j9kg00qf 1302 23 treated treat VBN cord-022526-j9kg00qf 1302 24 with with IN cord-022526-j9kg00qf 1302 25 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1302 26 have have VBP cord-022526-j9kg00qf 1302 27 closely closely RB cord-022526-j9kg00qf 1302 28 apposed appose VBN cord-022526-j9kg00qf 1302 29 tight tight JJ cord-022526-j9kg00qf 1302 30 junctions junction NNS cord-022526-j9kg00qf 1302 31 ( ( -LRB- cord-022526-j9kg00qf 1302 32 Figures figure NNS cord-022526-j9kg00qf 1302 33 13.5 13.5 CD cord-022526-j9kg00qf 1302 34 - - SYM cord-022526-j9kg00qf 1302 35 3 3 CD cord-022526-j9kg00qf 1302 36 and and CC cord-022526-j9kg00qf 1302 37 13.5 13.5 CD cord-022526-j9kg00qf 1302 38 - - SYM cord-022526-j9kg00qf 1302 39 4 4 CD cord-022526-j9kg00qf 1302 40 ) ) -RRB- cord-022526-j9kg00qf 1302 41 . . . cord-022526-j9kg00qf 1303 1 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1303 2 stimulate stimulate VBP cord-022526-j9kg00qf 1303 3 closure closure NN cord-022526-j9kg00qf 1303 4 of of IN cord-022526-j9kg00qf 1303 5 tight tight JJ cord-022526-j9kg00qf 1303 6 junctions junction NNS cord-022526-j9kg00qf 1303 7 via via IN cord-022526-j9kg00qf 1303 8 the the DT cord-022526-j9kg00qf 1303 9 second second JJ cord-022526-j9kg00qf 1303 10 messengers messenger NNS cord-022526-j9kg00qf 1303 11 cyclic cyclic JJ cord-022526-j9kg00qf 1303 12 adenosine adenosine NN cord-022526-j9kg00qf 1303 13 monophosphate monophosphate NN cord-022526-j9kg00qf 1303 14 and and CC cord-022526-j9kg00qf 1303 15 Ca Ca NNP cord-022526-j9kg00qf 1303 16 2 2 CD cord-022526-j9kg00qf 1303 17 + + CD cord-022526-j9kg00qf 1303 18 , , , cord-022526-j9kg00qf 1303 19 105 105 CD cord-022526-j9kg00qf 1303 20 which which WDT cord-022526-j9kg00qf 1303 21 interestingly interestingly RB cord-022526-j9kg00qf 1303 22 were be VBD cord-022526-j9kg00qf 1303 23 among among IN cord-022526-j9kg00qf 1303 24 the the DT cord-022526-j9kg00qf 1303 25 first first JJ cord-022526-j9kg00qf 1303 26 mediators mediator NNS cord-022526-j9kg00qf 1303 27 found find VBD cord-022526-j9kg00qf 1303 28 to to TO cord-022526-j9kg00qf 1303 29 modulate modulate VB cord-022526-j9kg00qf 1303 30 tight tight JJ cord-022526-j9kg00qf 1303 31 junction junction NN cord-022526-j9kg00qf 1303 32 permeability permeability NN cord-022526-j9kg00qf 1303 33 . . . cord-022526-j9kg00qf 1304 1 111 111 CD cord-022526-j9kg00qf 1304 2 , , , cord-022526-j9kg00qf 1304 3 112 112 CD cord-022526-j9kg00qf 1304 4 Such such JJ cord-022526-j9kg00qf 1304 5 tight tight JJ cord-022526-j9kg00qf 1304 6 junction junction NN cord-022526-j9kg00qf 1304 7 closure closure NN cord-022526-j9kg00qf 1304 8 is be VBZ cord-022526-j9kg00qf 1304 9 of of IN cord-022526-j9kg00qf 1304 10 importance importance NN cord-022526-j9kg00qf 1304 11 to to IN cord-022526-j9kg00qf 1304 12 patients patient NNS cord-022526-j9kg00qf 1304 13 with with IN cord-022526-j9kg00qf 1304 14 intestinal intestinal JJ cord-022526-j9kg00qf 1304 15 injury injury NN cord-022526-j9kg00qf 1304 16 that that WDT cord-022526-j9kg00qf 1304 17 are be VBP cord-022526-j9kg00qf 1304 18 treated treat VBN cord-022526-j9kg00qf 1304 19 with with IN cord-022526-j9kg00qf 1304 20 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 1304 21 , , , cord-022526-j9kg00qf 1304 22 because because IN cord-022526-j9kg00qf 1304 23 reduced reduce VBN cord-022526-j9kg00qf 1304 24 prostaglandin prostaglandin NN cord-022526-j9kg00qf 1304 25 levels level NNS cord-022526-j9kg00qf 1304 26 may may MD cord-022526-j9kg00qf 1304 27 result result VB cord-022526-j9kg00qf 1304 28 in in IN cord-022526-j9kg00qf 1304 29 increased increase VBN cord-022526-j9kg00qf 1304 30 intestinal intestinal JJ cord-022526-j9kg00qf 1304 31 permeability permeability NN cord-022526-j9kg00qf 1304 32 . . . cord-022526-j9kg00qf 1305 1 For for IN cord-022526-j9kg00qf 1305 2 example example NN cord-022526-j9kg00qf 1305 3 , , , cord-022526-j9kg00qf 1305 4 in in IN cord-022526-j9kg00qf 1305 5 a a DT cord-022526-j9kg00qf 1305 6 study study NN cord-022526-j9kg00qf 1305 7 on on IN cord-022526-j9kg00qf 1305 8 ischemic ischemic JJ cord-022526-j9kg00qf 1305 9 - - HYPH cord-022526-j9kg00qf 1305 10 injured injure VBN cord-022526-j9kg00qf 1305 11 porcine porcine JJ cord-022526-j9kg00qf 1305 12 ileum ileum NN cord-022526-j9kg00qf 1305 13 , , , cord-022526-j9kg00qf 1305 14 treatment treatment NN cord-022526-j9kg00qf 1305 15 with with IN cord-022526-j9kg00qf 1305 16 the the DT cord-022526-j9kg00qf 1305 17 NSAID NSAID NNP cord-022526-j9kg00qf 1305 18 indomethacin indomethacin NN cord-022526-j9kg00qf 1305 19 resulted result VBD cord-022526-j9kg00qf 1305 20 in in IN cord-022526-j9kg00qf 1305 21 a a DT cord-022526-j9kg00qf 1305 22 significant significant JJ cord-022526-j9kg00qf 1305 23 increase increase NN cord-022526-j9kg00qf 1305 24 in in IN cord-022526-j9kg00qf 1305 25 intestinal intestinal JJ cord-022526-j9kg00qf 1305 26 permeability permeability NN cord-022526-j9kg00qf 1305 27 to to IN cord-022526-j9kg00qf 1305 28 inulin inulin NN cord-022526-j9kg00qf 1305 29 and and CC cord-022526-j9kg00qf 1305 30 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1305 31 compared compare VBN cord-022526-j9kg00qf 1305 32 with with IN cord-022526-j9kg00qf 1305 33 tissues tissue NNS cord-022526-j9kg00qf 1305 34 that that WDT cord-022526-j9kg00qf 1305 35 were be VBD cord-022526-j9kg00qf 1305 36 treated treat VBN cord-022526-j9kg00qf 1305 37 additionally additionally RB cord-022526-j9kg00qf 1305 38 with with IN cord-022526-j9kg00qf 1305 39 PGI PGI NNP cord-022526-j9kg00qf 1305 40 2 2 CD cord-022526-j9kg00qf 1305 41 and and CC cord-022526-j9kg00qf 1305 42 PGE PGE NNP cord-022526-j9kg00qf 1305 43 2 2 CD cord-022526-j9kg00qf 1305 44 . . . cord-022526-j9kg00qf 1306 1 105 105 CD cord-022526-j9kg00qf 1306 2 SECTION section NN cord-022526-j9kg00qf 1306 3 13.5 13.5 CD cord-022526-j9kg00qf 1306 4 Pathophysiology pathophysiology NN cord-022526-j9kg00qf 1306 5 of of IN cord-022526-j9kg00qf 1306 6 Mucosal Mucosal NNP cord-022526-j9kg00qf 1306 7 Injury Injury NNP cord-022526-j9kg00qf 1306 8 and and CC cord-022526-j9kg00qf 1306 9 Repair Repair NNP cord-022526-j9kg00qf 1306 10 A a DT cord-022526-j9kg00qf 1306 11 B B NNP cord-022526-j9kg00qf 1306 12 Figure figure NN cord-022526-j9kg00qf 1306 13 13 13 CD cord-022526-j9kg00qf 1306 14 .5 .5 CD cord-022526-j9kg00qf 1306 15 - - SYM cord-022526-j9kg00qf 1306 16 4 4 CD cord-022526-j9kg00qf 1306 17 Ultrastructural Ultrastructural NNP cord-022526-j9kg00qf 1306 18 appearance appearance NN cord-022526-j9kg00qf 1306 19 of of IN cord-022526-j9kg00qf 1306 20 repairing repair VBG cord-022526-j9kg00qf 1306 21 ischemic ischemic JJ cord-022526-j9kg00qf 1306 22 - - HYPH cord-022526-j9kg00qf 1306 23 injured injured JJ cord-022526-j9kg00qf 1306 24 mucosa mucosa NN cord-022526-j9kg00qf 1306 25 . . . cord-022526-j9kg00qf 1307 1 A a DT cord-022526-j9kg00qf 1307 2 , , , cord-022526-j9kg00qf 1307 3 Restituting restitute VBG cord-022526-j9kg00qf 1307 4 epithelium epithelium NN cord-022526-j9kg00qf 1307 5 2 2 CD cord-022526-j9kg00qf 1307 6 hours hour NNS cord-022526-j9kg00qf 1307 7 following follow VBG cord-022526-j9kg00qf 1307 8 a a DT cord-022526-j9kg00qf 1307 9 1-hour 1-hour CD cord-022526-j9kg00qf 1307 10 ischemic ischemic JJ cord-022526-j9kg00qf 1307 11 episode episode NN cord-022526-j9kg00qf 1307 12 in in IN cord-022526-j9kg00qf 1307 13 the the DT cord-022526-j9kg00qf 1307 14 presence presence NN cord-022526-j9kg00qf 1307 15 of of IN cord-022526-j9kg00qf 1307 16 the the DT cord-022526-j9kg00qf 1307 17 nonselective nonselective JJ cord-022526-j9kg00qf 1307 18 cyclooxygenase cyclooxygenase JJ cord-022526-j9kg00qf 1307 19 inhibitor inhibitor NN cord-022526-j9kg00qf 1307 20 indomethacin indomethacin NN cord-022526-j9kg00qf 1307 21 . . . cord-022526-j9kg00qf 1308 1 Dilation dilation NN cord-022526-j9kg00qf 1308 2 of of IN cord-022526-j9kg00qf 1308 3 the the DT cord-022526-j9kg00qf 1308 4 interepithelial interepithelial JJ cord-022526-j9kg00qf 1308 5 space space NN cord-022526-j9kg00qf 1308 6 and and CC cord-022526-j9kg00qf 1308 7 the the DT cord-022526-j9kg00qf 1308 8 apical apical JJ cord-022526-j9kg00qf 1308 9 tight tight JJ cord-022526-j9kg00qf 1308 10 junction junction NN cord-022526-j9kg00qf 1308 11 ( ( -LRB- cord-022526-j9kg00qf 1308 12 arrows arrow NNS cord-022526-j9kg00qf 1308 13 ) ) -RRB- cord-022526-j9kg00qf 1308 14 correlates correlate VBZ cord-022526-j9kg00qf 1308 15 with with IN cord-022526-j9kg00qf 1308 16 a a DT cord-022526-j9kg00qf 1308 17 leaky leaky JJ cord-022526-j9kg00qf 1308 18 intestinal intestinal JJ cord-022526-j9kg00qf 1308 19 barrier barrier NN cord-022526-j9kg00qf 1308 20 , , , cord-022526-j9kg00qf 1308 21 B B NNP cord-022526-j9kg00qf 1308 22 , , , cord-022526-j9kg00qf 1308 23 Similar similar JJ cord-022526-j9kg00qf 1308 24 restituting restitute VBG cord-022526-j9kg00qf 1308 25 epithelium epithelium NN cord-022526-j9kg00qf 1308 26 had have VBD cord-022526-j9kg00qf 1308 27 been be VBN cord-022526-j9kg00qf 1308 28 treated treat VBN cord-022526-j9kg00qf 1308 29 additionally additionally RB cord-022526-j9kg00qf 1308 30 with with IN cord-022526-j9kg00qf 1308 31 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1308 32 E E NNP cord-022526-j9kg00qf 1308 33 2 2 CD cord-022526-j9kg00qf 1308 34 and and CC cord-022526-j9kg00qf 1308 35 I -PRON- PRP cord-022526-j9kg00qf 1308 36 2 2 CD cord-022526-j9kg00qf 1308 37 . . . cord-022526-j9kg00qf 1309 1 The the DT cord-022526-j9kg00qf 1309 2 close close JJ cord-022526-j9kg00qf 1309 3 apposition apposition NN cord-022526-j9kg00qf 1309 4 of of IN cord-022526-j9kg00qf 1309 5 the the DT cord-022526-j9kg00qf 1309 6 tight tight JJ cord-022526-j9kg00qf 1309 7 junction junction NN cord-022526-j9kg00qf 1309 8 ( ( -LRB- cord-022526-j9kg00qf 1309 9 arrows arrow NNS cord-022526-j9kg00qf 1309 10 ) ) -RRB- cord-022526-j9kg00qf 1309 11 and and CC cord-022526-j9kg00qf 1309 12 the the DT cord-022526-j9kg00qf 1309 13 interepithelial interepithelial JJ cord-022526-j9kg00qf 1309 14 space space NN cord-022526-j9kg00qf 1309 15 correlate correlate VBP cord-022526-j9kg00qf 1309 16 with with IN cord-022526-j9kg00qf 1309 17 normalization normalization NN cord-022526-j9kg00qf 1309 18 of of IN cord-022526-j9kg00qf 1309 19 intestinal intestinal JJ cord-022526-j9kg00qf 1309 20 barrier barrier NN cord-022526-j9kg00qf 1309 21 function function NN cord-022526-j9kg00qf 1309 22 . . . cord-022526-j9kg00qf 1310 1 1-cm 1-cm CD cord-022526-j9kg00qf 1310 2 bar bar NN cord-022526-j9kg00qf 1310 3 = = SYM cord-022526-j9kg00qf 1310 4 6 6 CD cord-022526-j9kg00qf 1310 5 µm µm NN cord-022526-j9kg00qf 1310 6 . . . cord-022526-j9kg00qf 1311 1 The the DT cord-022526-j9kg00qf 1311 2 process process NN cord-022526-j9kg00qf 1311 3 of of IN cord-022526-j9kg00qf 1311 4 restitution restitution NN cord-022526-j9kg00qf 1311 5 absolutely absolutely RB cord-022526-j9kg00qf 1311 6 depends depend VBZ cord-022526-j9kg00qf 1311 7 on on IN cord-022526-j9kg00qf 1311 8 a a DT cord-022526-j9kg00qf 1311 9 group group NN cord-022526-j9kg00qf 1311 10 of of IN cord-022526-j9kg00qf 1311 11 compounds compound NNS cord-022526-j9kg00qf 1311 12 called call VBN cord-022526-j9kg00qf 1311 13 polyamines polyamine NNS cord-022526-j9kg00qf 1311 14 . . . cord-022526-j9kg00qf 1312 1 113 113 CD cord-022526-j9kg00qf 1312 2 , , , cord-022526-j9kg00qf 1312 3 114 114 CD cord-022526-j9kg00qf 1313 1 The the DT cord-022526-j9kg00qf 1313 2 rate rate NN cord-022526-j9kg00qf 1313 3 - - HYPH cord-022526-j9kg00qf 1313 4 limiting limit VBG cord-022526-j9kg00qf 1313 5 enzyme enzyme NN cord-022526-j9kg00qf 1313 6 in in IN cord-022526-j9kg00qf 1313 7 the the DT cord-022526-j9kg00qf 1313 8 formation formation NN cord-022526-j9kg00qf 1313 9 of of IN cord-022526-j9kg00qf 1313 10 the the DT cord-022526-j9kg00qf 1313 11 polyamines polyamines NNP cord-022526-j9kg00qf 1313 12 spermine spermine NNP cord-022526-j9kg00qf 1313 13 , , , cord-022526-j9kg00qf 1313 14 spermidine spermidine NNP cord-022526-j9kg00qf 1313 15 , , , cord-022526-j9kg00qf 1313 16 and and CC cord-022526-j9kg00qf 1313 17 putrescine putrescine NN cord-022526-j9kg00qf 1313 18 is be VBZ cord-022526-j9kg00qf 1313 19 ornithine ornithine NN cord-022526-j9kg00qf 1313 20 decarboxylase decarboxylase NN cord-022526-j9kg00qf 1313 21 . . . cord-022526-j9kg00qf 1314 1 In in IN cord-022526-j9kg00qf 1314 2 rats rat NNS cord-022526-j9kg00qf 1314 3 with with IN cord-022526-j9kg00qf 1314 4 stress stress NN cord-022526-j9kg00qf 1314 5 - - HYPH cord-022526-j9kg00qf 1314 6 induced induce VBN cord-022526-j9kg00qf 1314 7 duodenal duodenal JJ cord-022526-j9kg00qf 1314 8 ulcers ulcer NNS cord-022526-j9kg00qf 1314 9 , , , cord-022526-j9kg00qf 1314 10 systemic systemic JJ cord-022526-j9kg00qf 1314 11 administration administration NN cord-022526-j9kg00qf 1314 12 of of IN cord-022526-j9kg00qf 1314 13 the the DT cord-022526-j9kg00qf 1314 14 ornithine ornithine NNP cord-022526-j9kg00qf 1314 15 decarboxylase decarboxylase NN cord-022526-j9kg00qf 1314 16 inhibitor inhibitor NN cord-022526-j9kg00qf 1314 17 α α NN cord-022526-j9kg00qf 1314 18 - - HYPH cord-022526-j9kg00qf 1314 19 difluoromethylornithine difluoromethylornithine NNP cord-022526-j9kg00qf 1314 20 significantly significantly RB cord-022526-j9kg00qf 1314 21 reduced reduce VBN cord-022526-j9kg00qf 1314 22 polyamine polyamine NN cord-022526-j9kg00qf 1314 23 levels level NNS cord-022526-j9kg00qf 1314 24 and and CC cord-022526-j9kg00qf 1314 25 greatly greatly RB cord-022526-j9kg00qf 1314 26 reduced reduce VBN cord-022526-j9kg00qf 1314 27 epithelial epithelial JJ cord-022526-j9kg00qf 1314 28 restitution restitution NN cord-022526-j9kg00qf 1314 29 . . . cord-022526-j9kg00qf 1315 1 Furthermore furthermore RB cord-022526-j9kg00qf 1315 2 , , , cord-022526-j9kg00qf 1315 3 intragastric intragastric JJ cord-022526-j9kg00qf 1315 4 treatment treatment NN cord-022526-j9kg00qf 1315 5 of of IN cord-022526-j9kg00qf 1315 6 these these DT cord-022526-j9kg00qf 1315 7 same same JJ cord-022526-j9kg00qf 1315 8 rats rat NNS cord-022526-j9kg00qf 1315 9 with with IN cord-022526-j9kg00qf 1315 10 putrescine putrescine NN cord-022526-j9kg00qf 1315 11 , , , cord-022526-j9kg00qf 1315 12 spermidine spermidine NNP cord-022526-j9kg00qf 1315 13 , , , cord-022526-j9kg00qf 1315 14 and and CC cord-022526-j9kg00qf 1315 15 spermine spermine NNP cord-022526-j9kg00qf 1315 16 prevented prevent VBD cord-022526-j9kg00qf 1315 17 the the DT cord-022526-j9kg00qf 1315 18 delayed delay VBN cord-022526-j9kg00qf 1315 19 mucosal mucosal JJ cord-022526-j9kg00qf 1315 20 repair repair NN cord-022526-j9kg00qf 1315 21 induced induce VBN cord-022526-j9kg00qf 1315 22 by by IN cord-022526-j9kg00qf 1315 23 α α NN cord-022526-j9kg00qf 1315 24 - - HYPH cord-022526-j9kg00qf 1315 25 difluoromethylornithine difluoromethylornithine NN cord-022526-j9kg00qf 1315 26 . . . cord-022526-j9kg00qf 1316 1 113 113 CD cord-022526-j9kg00qf 1317 1 Interestingly interestingly RB cord-022526-j9kg00qf 1317 2 , , , cord-022526-j9kg00qf 1317 3 gastric gastric JJ cord-022526-j9kg00qf 1317 4 tissue tissue NN cord-022526-j9kg00qf 1317 5 levels level NNS cord-022526-j9kg00qf 1317 6 of of IN cord-022526-j9kg00qf 1317 7 ornithine ornithine NN cord-022526-j9kg00qf 1317 8 decarboxylase decarboxylase NN cord-022526-j9kg00qf 1317 9 increased increase VBD cord-022526-j9kg00qf 1317 10 in in IN cord-022526-j9kg00qf 1317 11 rats rat NNS cord-022526-j9kg00qf 1317 12 with with IN cord-022526-j9kg00qf 1317 13 stress stress NN cord-022526-j9kg00qf 1317 14 - - HYPH cord-022526-j9kg00qf 1317 15 induced induce VBN cord-022526-j9kg00qf 1317 16 gastric gastric JJ cord-022526-j9kg00qf 1317 17 ulcers ulcer NNS cord-022526-j9kg00qf 1317 18 , , , cord-022526-j9kg00qf 1317 19 suggesting suggest VBG cord-022526-j9kg00qf 1317 20 that that IN cord-022526-j9kg00qf 1317 21 tissue tissue NN cord-022526-j9kg00qf 1317 22 injury injury NN cord-022526-j9kg00qf 1317 23 enhances enhance VBZ cord-022526-j9kg00qf 1317 24 polyamine polyamine NN cord-022526-j9kg00qf 1317 25 production production NN cord-022526-j9kg00qf 1317 26 , , , cord-022526-j9kg00qf 1317 27 which which WDT cord-022526-j9kg00qf 1317 28 may may MD cord-022526-j9kg00qf 1317 29 contribute contribute VB cord-022526-j9kg00qf 1317 30 to to IN cord-022526-j9kg00qf 1317 31 the the DT cord-022526-j9kg00qf 1317 32 normal normal JJ cord-022526-j9kg00qf 1317 33 rapid rapid JJ cord-022526-j9kg00qf 1317 34 rate rate NN cord-022526-j9kg00qf 1317 35 of of IN cord-022526-j9kg00qf 1317 36 epithelial epithelial JJ cord-022526-j9kg00qf 1317 37 restitution restitution NN cord-022526-j9kg00qf 1317 38 . . . cord-022526-j9kg00qf 1318 1 115 115 CD cord-022526-j9kg00qf 1319 1 The the DT cord-022526-j9kg00qf 1319 2 mechanisms mechanism NNS cord-022526-j9kg00qf 1319 3 whereby whereby WDT cord-022526-j9kg00qf 1319 4 polyamines polyamine NNS cord-022526-j9kg00qf 1319 5 stimulate stimulate VBP cord-022526-j9kg00qf 1319 6 epithelial epithelial JJ cord-022526-j9kg00qf 1319 7 restitution restitution NN cord-022526-j9kg00qf 1319 8 are be VBP cord-022526-j9kg00qf 1319 9 not not RB cord-022526-j9kg00qf 1319 10 clear clear JJ cord-022526-j9kg00qf 1319 11 . . . cord-022526-j9kg00qf 1320 1 McCormack McCormack NNP cord-022526-j9kg00qf 1320 2 , , , cord-022526-j9kg00qf 1320 3 Wang Wang NNP cord-022526-j9kg00qf 1320 4 , , , cord-022526-j9kg00qf 1320 5 Viar Viar NNP cord-022526-j9kg00qf 1320 6 , , , cord-022526-j9kg00qf 1320 7 et et NNP cord-022526-j9kg00qf 1320 8 al al NNP cord-022526-j9kg00qf 1320 9 . . NNP cord-022526-j9kg00qf 1320 10 hypothesized hypothesize VBD cord-022526-j9kg00qf 1320 11 that that IN cord-022526-j9kg00qf 1320 12 polyamines polyamine NNS cord-022526-j9kg00qf 1320 13 increase increase VBP cord-022526-j9kg00qf 1320 14 transglutaminase transglutaminase NN cord-022526-j9kg00qf 1320 15 activity activity NN cord-022526-j9kg00qf 1320 16 , , , cord-022526-j9kg00qf 1320 17 an an DT cord-022526-j9kg00qf 1320 18 enzyme enzyme NN cord-022526-j9kg00qf 1320 19 that that WDT cord-022526-j9kg00qf 1320 20 catalyzes catalyze VBZ cord-022526-j9kg00qf 1320 21 the the DT cord-022526-j9kg00qf 1320 22 cross cross NN cord-022526-j9kg00qf 1320 23 - - NN cord-022526-j9kg00qf 1320 24 linking linking NN cord-022526-j9kg00qf 1320 25 of of IN cord-022526-j9kg00qf 1320 26 cytoskeletal cytoskeletal JJ cord-022526-j9kg00qf 1320 27 and and CC cord-022526-j9kg00qf 1320 28 basement basement NN cord-022526-j9kg00qf 1320 29 membrane membrane NN cord-022526-j9kg00qf 1320 30 proteins protein NNS cord-022526-j9kg00qf 1320 31 . . . cord-022526-j9kg00qf 1321 1 116 116 CD cord-022526-j9kg00qf 1322 1 Further further JJ cord-022526-j9kg00qf 1322 2 investigation investigation NN cord-022526-j9kg00qf 1322 3 of of IN cord-022526-j9kg00qf 1322 4 the the DT cord-022526-j9kg00qf 1322 5 role role NN cord-022526-j9kg00qf 1322 6 of of IN cord-022526-j9kg00qf 1322 7 polyamines polyamine NNS cord-022526-j9kg00qf 1322 8 in in IN cord-022526-j9kg00qf 1322 9 IEC-6 IEC-6 NNP cord-022526-j9kg00qf 1322 10 cell cell NN cord-022526-j9kg00qf 1322 11 migration migration NN cord-022526-j9kg00qf 1322 12 showed show VBD cord-022526-j9kg00qf 1322 13 that that IN cord-022526-j9kg00qf 1322 14 depletion depletion NN cord-022526-j9kg00qf 1322 15 of of IN cord-022526-j9kg00qf 1322 16 polyamines polyamine NNS cord-022526-j9kg00qf 1322 17 resulted result VBD cord-022526-j9kg00qf 1322 18 in in IN cord-022526-j9kg00qf 1322 19 disruption disruption NN cord-022526-j9kg00qf 1322 20 of of IN cord-022526-j9kg00qf 1322 21 the the DT cord-022526-j9kg00qf 1322 22 cytoskeleton cytoskeleton NN cord-022526-j9kg00qf 1322 23 and and CC cord-022526-j9kg00qf 1322 24 reduced reduce VBD cord-022526-j9kg00qf 1322 25 the the DT cord-022526-j9kg00qf 1322 26 physical physical JJ cord-022526-j9kg00qf 1322 27 extension extension NN cord-022526-j9kg00qf 1322 28 of of IN cord-022526-j9kg00qf 1322 29 lamellipodia lamellipodia NNP cord-022526-j9kg00qf 1322 30 . . . cord-022526-j9kg00qf 1323 1 117 117 CD cord-022526-j9kg00qf 1323 2 More More JJR cord-022526-j9kg00qf 1323 3 recent recent JJ cord-022526-j9kg00qf 1323 4 studies study NNS cord-022526-j9kg00qf 1323 5 have have VBP cord-022526-j9kg00qf 1323 6 clarified clarify VBN cord-022526-j9kg00qf 1323 7 this this DT cord-022526-j9kg00qf 1323 8 pathway pathway NN cord-022526-j9kg00qf 1323 9 . . . cord-022526-j9kg00qf 1324 1 In in IN cord-022526-j9kg00qf 1324 2 particular particular JJ cord-022526-j9kg00qf 1324 3 , , , cord-022526-j9kg00qf 1324 4 polyamines polyamine NNS cord-022526-j9kg00qf 1324 5 have have VBP cord-022526-j9kg00qf 1324 6 been be VBN cord-022526-j9kg00qf 1324 7 shown show VBN cord-022526-j9kg00qf 1324 8 to to TO cord-022526-j9kg00qf 1324 9 regulate regulate VB cord-022526-j9kg00qf 1324 10 cytoskeletal cytoskeletal JJ cord-022526-j9kg00qf 1324 11 cellular cellular JJ cord-022526-j9kg00qf 1324 12 migration migration NN cord-022526-j9kg00qf 1324 13 via via IN cord-022526-j9kg00qf 1324 14 activation activation NN cord-022526-j9kg00qf 1324 15 of of IN cord-022526-j9kg00qf 1324 16 the the DT cord-022526-j9kg00qf 1324 17 small small JJ cord-022526-j9kg00qf 1324 18 guanosine guanosine NN cord-022526-j9kg00qf 1324 19 triphosphatase triphosphatase NN cord-022526-j9kg00qf 1324 20 - - HYPH cord-022526-j9kg00qf 1324 21 Rho rho NN cord-022526-j9kg00qf 1324 22 - - HYPH cord-022526-j9kg00qf 1324 23 A a NN cord-022526-j9kg00qf 1324 24 by by IN cord-022526-j9kg00qf 1324 25 elevating elevate VBG cord-022526-j9kg00qf 1324 26 intracellular intracellular JJ cord-022526-j9kg00qf 1325 1 Ca ca NN cord-022526-j9kg00qf 1325 2 2 2 CD cord-022526-j9kg00qf 1325 3 + + SYM cord-022526-j9kg00qf 1325 4 levels level NNS cord-022526-j9kg00qf 1325 5 . . . cord-022526-j9kg00qf 1326 1 These these DT cord-022526-j9kg00qf 1326 2 elevations elevation NNS cord-022526-j9kg00qf 1326 3 in in IN cord-022526-j9kg00qf 1326 4 Ca Ca NNP cord-022526-j9kg00qf 1326 5 2 2 CD cord-022526-j9kg00qf 1326 6 + + CC cord-022526-j9kg00qf 1326 7 result result NN cord-022526-j9kg00qf 1326 8 from from IN cord-022526-j9kg00qf 1326 9 polyamine polyamine NN cord-022526-j9kg00qf 1326 10 regulation regulation NN cord-022526-j9kg00qf 1326 11 of of IN cord-022526-j9kg00qf 1326 12 expression expression NN cord-022526-j9kg00qf 1326 13 of of IN cord-022526-j9kg00qf 1326 14 voltagegated voltagegate VBN cord-022526-j9kg00qf 1326 15 K K NNP cord-022526-j9kg00qf 1326 16 + + CC cord-022526-j9kg00qf 1326 17 channels channel NNS cord-022526-j9kg00qf 1326 18 and and CC cord-022526-j9kg00qf 1326 19 altered alter VBD cord-022526-j9kg00qf 1326 20 membrane membrane NN cord-022526-j9kg00qf 1326 21 electric electric JJ cord-022526-j9kg00qf 1326 22 potential potential NN cord-022526-j9kg00qf 1326 23 . . . cord-022526-j9kg00qf 1327 1 118 118 CD cord-022526-j9kg00qf 1328 1 Polyamines polyamine NNS cord-022526-j9kg00qf 1328 2 also also RB cord-022526-j9kg00qf 1328 3 play play VBP cord-022526-j9kg00qf 1328 4 a a DT cord-022526-j9kg00qf 1328 5 role role NN cord-022526-j9kg00qf 1328 6 in in IN cord-022526-j9kg00qf 1328 7 the the DT cord-022526-j9kg00qf 1328 8 normal normal JJ cord-022526-j9kg00qf 1328 9 physiologic physiologic JJ cord-022526-j9kg00qf 1328 10 regulation regulation NN cord-022526-j9kg00qf 1328 11 of of IN cord-022526-j9kg00qf 1328 12 crypt crypt JJ cord-022526-j9kg00qf 1328 13 cell cell NN cord-022526-j9kg00qf 1328 14 proliferation proliferation NN cord-022526-j9kg00qf 1328 15 and and CC cord-022526-j9kg00qf 1328 16 differentiation differentiation NN cord-022526-j9kg00qf 1328 17 . . . cord-022526-j9kg00qf 1329 1 119,120 119,120 CD cord-022526-j9kg00qf 1330 1 Polyamines polyamine NNS cord-022526-j9kg00qf 1330 2 are be VBP cord-022526-j9kg00qf 1330 3 produced produce VBN cord-022526-j9kg00qf 1330 4 by by IN cord-022526-j9kg00qf 1330 5 fully fully RB cord-022526-j9kg00qf 1330 6 differentiated differentiate VBN cord-022526-j9kg00qf 1330 7 enterocytes enterocyte NNS cord-022526-j9kg00qf 1330 8 at at IN cord-022526-j9kg00qf 1330 9 the the DT cord-022526-j9kg00qf 1330 10 tip tip NN cord-022526-j9kg00qf 1330 11 of of IN cord-022526-j9kg00qf 1330 12 the the DT cord-022526-j9kg00qf 1330 13 villus villus NN cord-022526-j9kg00qf 1330 14 and and CC cord-022526-j9kg00qf 1330 15 may may MD cord-022526-j9kg00qf 1330 16 reach reach VB cord-022526-j9kg00qf 1330 17 the the DT cord-022526-j9kg00qf 1330 18 crypt crypt NN cord-022526-j9kg00qf 1330 19 within within IN cord-022526-j9kg00qf 1330 20 sloughed slough VBN cord-022526-j9kg00qf 1330 21 luminal luminal JJ cord-022526-j9kg00qf 1330 22 epithelium epithelium NN cord-022526-j9kg00qf 1330 23 or or CC cord-022526-j9kg00qf 1330 24 via via IN cord-022526-j9kg00qf 1330 25 local local JJ cord-022526-j9kg00qf 1330 26 villous villous NNP cord-022526-j9kg00qf 1330 27 circulation circulation NN cord-022526-j9kg00qf 1330 28 . . . cord-022526-j9kg00qf 1331 1 121 121 CD cord-022526-j9kg00qf 1332 1 Following follow VBG cord-022526-j9kg00qf 1332 2 intestinal intestinal JJ cord-022526-j9kg00qf 1332 3 injury injury NN cord-022526-j9kg00qf 1332 4 , , , cord-022526-j9kg00qf 1332 5 polyamines polyamine NNS cord-022526-j9kg00qf 1332 6 appear appear VBP cord-022526-j9kg00qf 1332 7 to to TO cord-022526-j9kg00qf 1332 8 stimulate stimulate VB cord-022526-j9kg00qf 1332 9 enhanced enhanced JJ cord-022526-j9kg00qf 1332 10 proliferation proliferation NN cord-022526-j9kg00qf 1332 11 by by IN cord-022526-j9kg00qf 1332 12 increasing increase VBG cord-022526-j9kg00qf 1332 13 the the DT cord-022526-j9kg00qf 1332 14 expression expression NN cord-022526-j9kg00qf 1332 15 of of IN cord-022526-j9kg00qf 1332 16 protooncogenes protooncogene NNS cord-022526-j9kg00qf 1332 17 , , , cord-022526-j9kg00qf 1332 18 which which WDT cord-022526-j9kg00qf 1332 19 control control VBP cord-022526-j9kg00qf 1332 20 the the DT cord-022526-j9kg00qf 1332 21 cell cell NN cord-022526-j9kg00qf 1332 22 cycle cycle NN cord-022526-j9kg00qf 1332 23 . . . cord-022526-j9kg00qf 1333 1 122 122 CD cord-022526-j9kg00qf 1334 1 The the DT cord-022526-j9kg00qf 1334 2 mechanism mechanism NN cord-022526-j9kg00qf 1334 3 whereby whereby WRB cord-022526-j9kg00qf 1334 4 polyamines polyamines NNP cord-022526-j9kg00qf 1334 5 influence influence NN cord-022526-j9kg00qf 1334 6 gene gene NN cord-022526-j9kg00qf 1334 7 expression expression NN cord-022526-j9kg00qf 1334 8 likely likely RB cord-022526-j9kg00qf 1334 9 relates relate VBZ cord-022526-j9kg00qf 1334 10 to to IN cord-022526-j9kg00qf 1334 11 the the DT cord-022526-j9kg00qf 1334 12 cationic cationic JJ cord-022526-j9kg00qf 1334 13 nature nature NN cord-022526-j9kg00qf 1334 14 of of IN cord-022526-j9kg00qf 1334 15 these these DT cord-022526-j9kg00qf 1334 16 compounds compound NNS cord-022526-j9kg00qf 1334 17 , , , cord-022526-j9kg00qf 1334 18 which which WDT cord-022526-j9kg00qf 1334 19 may may MD cord-022526-j9kg00qf 1334 20 influence influence VB cord-022526-j9kg00qf 1334 21 the the DT cord-022526-j9kg00qf 1334 22 tertiary tertiary JJ cord-022526-j9kg00qf 1334 23 structure structure NN cord-022526-j9kg00qf 1334 24 of of IN cord-022526-j9kg00qf 1334 25 negatively negatively RB cord-022526-j9kg00qf 1334 26 charged charge VBN cord-022526-j9kg00qf 1334 27 DNA DNA NNP cord-022526-j9kg00qf 1334 28 and and CC cord-022526-j9kg00qf 1334 29 RNA RNA NNP cord-022526-j9kg00qf 1334 30 . . . cord-022526-j9kg00qf 1335 1 113 113 CD cord-022526-j9kg00qf 1335 2 _SP cord-022526-j9kg00qf 1336 1 Locally locally RB cord-022526-j9kg00qf 1336 2 produced produce VBN cord-022526-j9kg00qf 1336 3 growth growth NN cord-022526-j9kg00qf 1336 4 factors factor NNS cord-022526-j9kg00qf 1336 5 - - : cord-022526-j9kg00qf 1336 6 including include VBG cord-022526-j9kg00qf 1336 7 epidermal epidermal JJ cord-022526-j9kg00qf 1336 8 growth growth NN cord-022526-j9kg00qf 1336 9 factor factor NN cord-022526-j9kg00qf 1336 10 ( ( -LRB- cord-022526-j9kg00qf 1336 11 EGF EGF NNP cord-022526-j9kg00qf 1336 12 ) ) -RRB- cord-022526-j9kg00qf 1336 13 , , , cord-022526-j9kg00qf 1336 14 transforming transform VBG cord-022526-j9kg00qf 1336 15 growth growth NN cord-022526-j9kg00qf 1336 16 factor factor NN cord-022526-j9kg00qf 1336 17 α α NN cord-022526-j9kg00qf 1336 18 ( ( -LRB- cord-022526-j9kg00qf 1336 19 TGF TGF NNP cord-022526-j9kg00qf 1336 20 - - HYPH cord-022526-j9kg00qf 1336 21 α α NNP cord-022526-j9kg00qf 1336 22 ) ) -RRB- cord-022526-j9kg00qf 1336 23 , , , cord-022526-j9kg00qf 1336 24 TGF TGF NNP cord-022526-j9kg00qf 1336 25 - - HYPH cord-022526-j9kg00qf 1336 26 β β NNP cord-022526-j9kg00qf 1336 27 , , , cord-022526-j9kg00qf 1336 28 and and CC cord-022526-j9kg00qf 1336 29 hepatocyte hepatocyte NN cord-022526-j9kg00qf 1336 30 growth growth NN cord-022526-j9kg00qf 1336 31 factor factor NN cord-022526-j9kg00qf 1336 32 - - : cord-022526-j9kg00qf 1336 33 have have VBP cord-022526-j9kg00qf 1336 34 the the DT cord-022526-j9kg00qf 1336 35 ability ability NN cord-022526-j9kg00qf 1336 36 to to TO cord-022526-j9kg00qf 1336 37 modulate modulate VB cord-022526-j9kg00qf 1336 38 mucosal mucosal JJ cord-022526-j9kg00qf 1336 39 recovery recovery NN cord-022526-j9kg00qf 1336 40 . . . cord-022526-j9kg00qf 1337 1 The the DT cord-022526-j9kg00qf 1337 2 most most RBS cord-022526-j9kg00qf 1337 3 important important JJ cord-022526-j9kg00qf 1337 4 of of IN cord-022526-j9kg00qf 1337 5 these these DT cord-022526-j9kg00qf 1337 6 growth growth NN cord-022526-j9kg00qf 1337 7 factors factor NNS cord-022526-j9kg00qf 1337 8 in in IN cord-022526-j9kg00qf 1337 9 early early JJ cord-022526-j9kg00qf 1337 10 mucosal mucosal JJ cord-022526-j9kg00qf 1337 11 repair repair NN cord-022526-j9kg00qf 1337 12 events event NNS cord-022526-j9kg00qf 1337 13 is be VBZ cord-022526-j9kg00qf 1337 14 TGF TGF NNP cord-022526-j9kg00qf 1337 15 - - HYPH cord-022526-j9kg00qf 1337 16 β β NNP cord-022526-j9kg00qf 1337 17 , , , cord-022526-j9kg00qf 1337 18 which which WDT cord-022526-j9kg00qf 1337 19 is be VBZ cord-022526-j9kg00qf 1337 20 a a DT cord-022526-j9kg00qf 1337 21 potent potent JJ cord-022526-j9kg00qf 1337 22 stimulus stimulus NN cord-022526-j9kg00qf 1337 23 of of IN cord-022526-j9kg00qf 1337 24 epithelial epithelial JJ cord-022526-j9kg00qf 1337 25 restitution restitution NN cord-022526-j9kg00qf 1337 26 and and CC cord-022526-j9kg00qf 1337 27 modulator modulator NN cord-022526-j9kg00qf 1337 28 of of IN cord-022526-j9kg00qf 1337 29 the the DT cord-022526-j9kg00qf 1337 30 extracellular extracellular JJ cord-022526-j9kg00qf 1337 31 matrix matrix NN cord-022526-j9kg00qf 1337 32 . . . cord-022526-j9kg00qf 1338 1 26 26 CD cord-022526-j9kg00qf 1338 2 Neutralization neutralization NN cord-022526-j9kg00qf 1338 3 of of IN cord-022526-j9kg00qf 1338 4 TGF TGF NNP cord-022526-j9kg00qf 1338 5 - - HYPH cord-022526-j9kg00qf 1338 6 β β NN cord-022526-j9kg00qf 1338 7 retards retards VBP cord-022526-j9kg00qf 1338 8 epithelial epithelial JJ cord-022526-j9kg00qf 1338 9 migration migration NN cord-022526-j9kg00qf 1338 10 in in IN cord-022526-j9kg00qf 1338 11 vitro vitro FW cord-022526-j9kg00qf 1338 12 , , , cord-022526-j9kg00qf 1338 13 and and CC cord-022526-j9kg00qf 1338 14 TGF TGF NNP cord-022526-j9kg00qf 1338 15 - - HYPH cord-022526-j9kg00qf 1338 16 β β NNP cord-022526-j9kg00qf 1338 17 apparently apparently RB cord-022526-j9kg00qf 1338 18 may may MD cord-022526-j9kg00qf 1338 19 serve serve VB cord-022526-j9kg00qf 1338 20 as as IN cord-022526-j9kg00qf 1338 21 a a DT cord-022526-j9kg00qf 1338 22 point point NN cord-022526-j9kg00qf 1338 23 of of IN cord-022526-j9kg00qf 1338 24 convergence convergence NN cord-022526-j9kg00qf 1338 25 for for IN cord-022526-j9kg00qf 1338 26 mediators mediator NNS cord-022526-j9kg00qf 1338 27 of of IN cord-022526-j9kg00qf 1338 28 restitution restitution NN cord-022526-j9kg00qf 1338 29 , , , cord-022526-j9kg00qf 1338 30 because because IN cord-022526-j9kg00qf 1338 31 neutralizing neutralize VBG cord-022526-j9kg00qf 1338 32 TGF TGF NNP cord-022526-j9kg00qf 1338 33 - - HYPH cord-022526-j9kg00qf 1338 34 β β NNP cord-022526-j9kg00qf 1338 35 also also RB cord-022526-j9kg00qf 1338 36 inhibits inhibit VBZ cord-022526-j9kg00qf 1338 37 the the DT cord-022526-j9kg00qf 1338 38 effects effect NNS cord-022526-j9kg00qf 1338 39 of of IN cord-022526-j9kg00qf 1338 40 other other JJ cord-022526-j9kg00qf 1338 41 peptides peptide NNS cord-022526-j9kg00qf 1338 42 . . . cord-022526-j9kg00qf 1339 1 However however RB cord-022526-j9kg00qf 1339 2 , , , cord-022526-j9kg00qf 1339 3 TGF TGF NNP cord-022526-j9kg00qf 1339 4 - - HYPH cord-022526-j9kg00qf 1339 5 β β NNP cord-022526-j9kg00qf 1339 6 paradoxically paradoxically RB cord-022526-j9kg00qf 1339 7 inhibits inhibit VBZ cord-022526-j9kg00qf 1339 8 epithelial epithelial JJ cord-022526-j9kg00qf 1339 9 proliferation proliferation NN cord-022526-j9kg00qf 1339 10 , , , cord-022526-j9kg00qf 1339 11 thereby thereby RB cord-022526-j9kg00qf 1339 12 reducing reduce VBG cord-022526-j9kg00qf 1339 13 the the DT cord-022526-j9kg00qf 1339 14 supply supply NN cord-022526-j9kg00qf 1339 15 of of IN cord-022526-j9kg00qf 1339 16 new new JJ cord-022526-j9kg00qf 1339 17 enterocytes enterocyte NNS cord-022526-j9kg00qf 1339 18 for for IN cord-022526-j9kg00qf 1339 19 mucosal mucosal JJ cord-022526-j9kg00qf 1339 20 repair repair NN cord-022526-j9kg00qf 1339 21 . . . cord-022526-j9kg00qf 1340 1 Conversely conversely RB cord-022526-j9kg00qf 1340 2 , , , cord-022526-j9kg00qf 1340 3 EGF EGF NNP cord-022526-j9kg00qf 1340 4 , , , cord-022526-j9kg00qf 1340 5 produced produce VBN cord-022526-j9kg00qf 1340 6 by by IN cord-022526-j9kg00qf 1340 7 the the DT cord-022526-j9kg00qf 1340 8 salivary salivary NN cord-022526-j9kg00qf 1340 9 glands gland NNS cord-022526-j9kg00qf 1340 10 and and CC cord-022526-j9kg00qf 1340 11 duodenal duodenal JJ cord-022526-j9kg00qf 1340 12 Brunner Brunner NNP cord-022526-j9kg00qf 1340 13 's 's POS cord-022526-j9kg00qf 1340 14 glands gland NNS cord-022526-j9kg00qf 1340 15 , , , cord-022526-j9kg00qf 1340 16 and and CC cord-022526-j9kg00qf 1340 17 the the DT cord-022526-j9kg00qf 1340 18 related related JJ cord-022526-j9kg00qf 1340 19 TGF TGF NNP cord-022526-j9kg00qf 1340 20 - - HYPH cord-022526-j9kg00qf 1340 21 α α NNP cord-022526-j9kg00qf 1340 22 , , , cord-022526-j9kg00qf 1340 23 produced produce VBN cord-022526-j9kg00qf 1340 24 by by IN cord-022526-j9kg00qf 1340 25 small small JJ cord-022526-j9kg00qf 1340 26 intestinal intestinal JJ cord-022526-j9kg00qf 1340 27 enterocytes enterocyte NNS cord-022526-j9kg00qf 1340 28 , , , cord-022526-j9kg00qf 1340 29 are be VBP cord-022526-j9kg00qf 1340 30 potent potent JJ cord-022526-j9kg00qf 1340 31 stimulants stimulant NNS cord-022526-j9kg00qf 1340 32 of of IN cord-022526-j9kg00qf 1340 33 enterocyte enterocyte NN cord-022526-j9kg00qf 1340 34 proliferation proliferation NN cord-022526-j9kg00qf 1340 35 . . . cord-022526-j9kg00qf 1341 1 These these DT cord-022526-j9kg00qf 1341 2 growth growth NN cord-022526-j9kg00qf 1341 3 factors factor NNS cord-022526-j9kg00qf 1341 4 share share VBP cord-022526-j9kg00qf 1341 5 approximately approximately RB cord-022526-j9kg00qf 1341 6 30 30 CD cord-022526-j9kg00qf 1341 7 % % NN cord-022526-j9kg00qf 1341 8 of of IN cord-022526-j9kg00qf 1341 9 their -PRON- PRP$ cord-022526-j9kg00qf 1341 10 amino amino NN cord-022526-j9kg00qf 1341 11 acid acid NN cord-022526-j9kg00qf 1341 12 structure structure NN cord-022526-j9kg00qf 1341 13 , , , cord-022526-j9kg00qf 1341 14 bind bind VB cord-022526-j9kg00qf 1341 15 to to IN cord-022526-j9kg00qf 1341 16 the the DT cord-022526-j9kg00qf 1341 17 same same JJ cord-022526-j9kg00qf 1341 18 receptor receptor NN cord-022526-j9kg00qf 1341 19 on on IN cord-022526-j9kg00qf 1341 20 the the DT cord-022526-j9kg00qf 1341 21 basolateral basolateral JJ cord-022526-j9kg00qf 1341 22 surface surface NN cord-022526-j9kg00qf 1341 23 of of IN cord-022526-j9kg00qf 1341 24 enterocytes enterocyte NNS cord-022526-j9kg00qf 1341 25 , , , cord-022526-j9kg00qf 1341 26 and and CC cord-022526-j9kg00qf 1341 27 are be VBP cord-022526-j9kg00qf 1341 28 not not RB cord-022526-j9kg00qf 1341 29 related relate VBN cord-022526-j9kg00qf 1341 30 to to IN cord-022526-j9kg00qf 1341 31 TGF TGF NNP cord-022526-j9kg00qf 1341 32 - - HYPH cord-022526-j9kg00qf 1341 33 β β NNP cord-022526-j9kg00qf 1341 34 . . . cord-022526-j9kg00qf 1342 1 123 123 CD cord-022526-j9kg00qf 1343 1 The the DT cord-022526-j9kg00qf 1343 2 physiologic physiologic JJ cord-022526-j9kg00qf 1343 3 role role NN cord-022526-j9kg00qf 1343 4 of of IN cord-022526-j9kg00qf 1343 5 EGF EGF NNP cord-022526-j9kg00qf 1343 6 is be VBZ cord-022526-j9kg00qf 1343 7 difficult difficult JJ cord-022526-j9kg00qf 1343 8 to to TO cord-022526-j9kg00qf 1343 9 discern discern VB cord-022526-j9kg00qf 1343 10 because because IN cord-022526-j9kg00qf 1343 11 it -PRON- PRP cord-022526-j9kg00qf 1343 12 is be VBZ cord-022526-j9kg00qf 1343 13 present present JJ cord-022526-j9kg00qf 1343 14 in in IN cord-022526-j9kg00qf 1343 15 the the DT cord-022526-j9kg00qf 1343 16 intestinal intestinal JJ cord-022526-j9kg00qf 1343 17 lumen lumen NN cord-022526-j9kg00qf 1343 18 , , , cord-022526-j9kg00qf 1343 19 with with IN cord-022526-j9kg00qf 1343 20 no no DT cord-022526-j9kg00qf 1343 21 apparent apparent JJ cord-022526-j9kg00qf 1343 22 access access NN cord-022526-j9kg00qf 1343 23 to to IN cord-022526-j9kg00qf 1343 24 its -PRON- PRP$ cord-022526-j9kg00qf 1343 25 basally basally RB cord-022526-j9kg00qf 1343 26 located locate VBN cord-022526-j9kg00qf 1343 27 receptor receptor NN cord-022526-j9kg00qf 1343 28 . . . cord-022526-j9kg00qf 1344 1 However however RB cord-022526-j9kg00qf 1344 2 , , , cord-022526-j9kg00qf 1344 3 EGF EGF NNP cord-022526-j9kg00qf 1344 4 has have VBZ cord-022526-j9kg00qf 1344 5 been be VBN cord-022526-j9kg00qf 1344 6 proposed propose VBN cord-022526-j9kg00qf 1344 7 to to TO cord-022526-j9kg00qf 1344 8 act act VB cord-022526-j9kg00qf 1344 9 as as IN cord-022526-j9kg00qf 1344 10 a a DT cord-022526-j9kg00qf 1344 11 " " `` cord-022526-j9kg00qf 1344 12 surveillance surveillance NN cord-022526-j9kg00qf 1344 13 agent agent NN cord-022526-j9kg00qf 1344 14 " " '' cord-022526-j9kg00qf 1344 15 that that WDT cord-022526-j9kg00qf 1344 16 gains gain VBZ cord-022526-j9kg00qf 1344 17 access access NN cord-022526-j9kg00qf 1344 18 to to IN cord-022526-j9kg00qf 1344 19 its -PRON- PRP$ cord-022526-j9kg00qf 1344 20 receptor receptor NN cord-022526-j9kg00qf 1344 21 during during IN cord-022526-j9kg00qf 1344 22 epithelial epithelial JJ cord-022526-j9kg00qf 1344 23 injury injury NN cord-022526-j9kg00qf 1344 24 ( ( -LRB- cord-022526-j9kg00qf 1344 25 when when WRB cord-022526-j9kg00qf 1344 26 the the DT cord-022526-j9kg00qf 1344 27 EGF EGF NNP cord-022526-j9kg00qf 1344 28 receptor receptor NN cord-022526-j9kg00qf 1344 29 likely likely RB cord-022526-j9kg00qf 1344 30 would would MD cord-022526-j9kg00qf 1344 31 be be VB cord-022526-j9kg00qf 1344 32 exposed expose VBN cord-022526-j9kg00qf 1344 33 ) ) -RRB- cord-022526-j9kg00qf 1344 34 to to TO cord-022526-j9kg00qf 1344 35 stimulate stimulate VB cord-022526-j9kg00qf 1344 36 proliferation proliferation NN cord-022526-j9kg00qf 1344 37 . . . cord-022526-j9kg00qf 1345 1 124 124 CD cord-022526-j9kg00qf 1345 2 TGF TGF NNP cord-022526-j9kg00qf 1346 1 -α -α NFP cord-022526-j9kg00qf 1346 2 presumably presumably RB cord-022526-j9kg00qf 1346 3 has have VBZ cord-022526-j9kg00qf 1346 4 a a DT cord-022526-j9kg00qf 1346 5 similar similar JJ cord-022526-j9kg00qf 1346 6 role role NN cord-022526-j9kg00qf 1346 7 , , , cord-022526-j9kg00qf 1346 8 but but CC cord-022526-j9kg00qf 1346 9 it -PRON- PRP cord-022526-j9kg00qf 1346 10 is be VBZ cord-022526-j9kg00qf 1346 11 present present JJ cord-022526-j9kg00qf 1346 12 in in IN cord-022526-j9kg00qf 1346 13 greater great JJR cord-022526-j9kg00qf 1346 14 concentrations concentration NNS cord-022526-j9kg00qf 1346 15 in in IN cord-022526-j9kg00qf 1346 16 the the DT cord-022526-j9kg00qf 1346 17 small small JJ cord-022526-j9kg00qf 1346 18 intestine intestine NN cord-022526-j9kg00qf 1346 19 because because IN cord-022526-j9kg00qf 1346 20 it -PRON- PRP cord-022526-j9kg00qf 1346 21 is be VBZ cord-022526-j9kg00qf 1346 22 produced produce VBN cord-022526-j9kg00qf 1346 23 by by IN cord-022526-j9kg00qf 1346 24 differentiated differentiate VBN cord-022526-j9kg00qf 1346 25 villous villous NNP cord-022526-j9kg00qf 1346 26 enterocytes enterocytes NNP cord-022526-j9kg00qf 1346 27 . . . cord-022526-j9kg00qf 1347 1 The the DT cord-022526-j9kg00qf 1347 2 mature mature JJ cord-022526-j9kg00qf 1347 3 peptide peptide NN cord-022526-j9kg00qf 1347 4 is be VBZ cord-022526-j9kg00qf 1347 5 cleaved cleave VBN cord-022526-j9kg00qf 1347 6 from from IN cord-022526-j9kg00qf 1347 7 the the DT cord-022526-j9kg00qf 1347 8 extracellular extracellular JJ cord-022526-j9kg00qf 1347 9 component component NN cord-022526-j9kg00qf 1347 10 of of IN cord-022526-j9kg00qf 1347 11 the the DT cord-022526-j9kg00qf 1347 12 transmembrane transmembrane JJ cord-022526-j9kg00qf 1347 13 TGF TGF NNP cord-022526-j9kg00qf 1347 14 - - HYPH cord-022526-j9kg00qf 1347 15 α α NN cord-022526-j9kg00qf 1347 16 precursor precursor NN cord-022526-j9kg00qf 1347 17 and and CC cord-022526-j9kg00qf 1347 18 released release VBN cord-022526-j9kg00qf 1347 19 into into IN cord-022526-j9kg00qf 1347 20 the the DT cord-022526-j9kg00qf 1347 21 lumen lumen NN cord-022526-j9kg00qf 1347 22 . . . cord-022526-j9kg00qf 1348 1 123 123 CD cord-022526-j9kg00qf 1349 1 Another another DT cord-022526-j9kg00qf 1349 2 group group NN cord-022526-j9kg00qf 1349 3 of of IN cord-022526-j9kg00qf 1349 4 proreparative proreparative JJ cord-022526-j9kg00qf 1349 5 peptides peptide NNS cord-022526-j9kg00qf 1349 6 produced produce VBN cord-022526-j9kg00qf 1349 7 within within IN cord-022526-j9kg00qf 1349 8 the the DT cord-022526-j9kg00qf 1349 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1349 10 tract tract NN cord-022526-j9kg00qf 1349 11 are be VBP cord-022526-j9kg00qf 1349 12 the the DT cord-022526-j9kg00qf 1349 13 trefoil trefoil NN cord-022526-j9kg00qf 1349 14 peptides peptide NNS cord-022526-j9kg00qf 1349 15 . . . cord-022526-j9kg00qf 1350 1 Under under IN cord-022526-j9kg00qf 1350 2 physiologic physiologic JJ cord-022526-j9kg00qf 1350 3 conditions condition NNS cord-022526-j9kg00qf 1350 4 , , , cord-022526-j9kg00qf 1350 5 trefoil trefoil NN cord-022526-j9kg00qf 1350 6 peptides peptide NNS cord-022526-j9kg00qf 1350 7 are be VBP cord-022526-j9kg00qf 1350 8 secreted secrete VBN cord-022526-j9kg00qf 1350 9 by by IN cord-022526-j9kg00qf 1350 10 mucus mucus NN cord-022526-j9kg00qf 1350 11 - - HYPH cord-022526-j9kg00qf 1350 12 producing produce VBG cord-022526-j9kg00qf 1350 13 cells cell NNS cord-022526-j9kg00qf 1350 14 at at IN cord-022526-j9kg00qf 1350 15 distinct distinct JJ cord-022526-j9kg00qf 1350 16 anatomic anatomic JJ cord-022526-j9kg00qf 1350 17 sites site NNS cord-022526-j9kg00qf 1350 18 . . . cord-022526-j9kg00qf 1351 1 For for IN cord-022526-j9kg00qf 1351 2 example example NN cord-022526-j9kg00qf 1351 3 , , , cord-022526-j9kg00qf 1351 4 gastric gastric JJ cord-022526-j9kg00qf 1351 5 epithelium epithelium NN cord-022526-j9kg00qf 1351 6 produces produce VBZ cord-022526-j9kg00qf 1351 7 the the DT cord-022526-j9kg00qf 1351 8 trefoil trefoil NN cord-022526-j9kg00qf 1351 9 peptide peptide NN cord-022526-j9kg00qf 1351 10 pS2 ps2 NN cord-022526-j9kg00qf 1351 11 , , , cord-022526-j9kg00qf 1351 12 whereas whereas IN cord-022526-j9kg00qf 1351 13 the the DT cord-022526-j9kg00qf 1351 14 small small JJ cord-022526-j9kg00qf 1351 15 and and CC cord-022526-j9kg00qf 1351 16 large large JJ cord-022526-j9kg00qf 1351 17 intestine intestine NN cord-022526-j9kg00qf 1351 18 mucosa mucosa NN cord-022526-j9kg00qf 1351 19 produce produce VBP cord-022526-j9kg00qf 1351 20 intestinal intestinal JJ cord-022526-j9kg00qf 1351 21 trefoil trefoil NN cord-022526-j9kg00qf 1351 22 peptide peptide NN cord-022526-j9kg00qf 1351 23 . . . cord-022526-j9kg00qf 1352 1 125 125 CD cord-022526-j9kg00qf 1353 1 However however RB cord-022526-j9kg00qf 1353 2 , , , cord-022526-j9kg00qf 1353 3 any any DT cord-022526-j9kg00qf 1353 4 of of IN cord-022526-j9kg00qf 1353 5 the the DT cord-022526-j9kg00qf 1353 6 trefoil trefoil NN cord-022526-j9kg00qf 1353 7 peptides peptide NNS cord-022526-j9kg00qf 1353 8 may may MD cord-022526-j9kg00qf 1353 9 be be VB cord-022526-j9kg00qf 1353 10 upregulated upregulate VBN cord-022526-j9kg00qf 1353 11 within within IN cord-022526-j9kg00qf 1353 12 repairing repair VBG cord-022526-j9kg00qf 1353 13 epithelium epithelium NN cord-022526-j9kg00qf 1353 14 regardless regardless RB cord-022526-j9kg00qf 1353 15 of of IN cord-022526-j9kg00qf 1353 16 anatomic anatomic JJ cord-022526-j9kg00qf 1353 17 site site NN cord-022526-j9kg00qf 1353 18 . . . cord-022526-j9kg00qf 1354 1 26 26 CD cord-022526-j9kg00qf 1354 2 , , , cord-022526-j9kg00qf 1354 3 126 126 CD cord-022526-j9kg00qf 1355 1 In in IN cord-022526-j9kg00qf 1355 2 addition addition NN cord-022526-j9kg00qf 1355 3 , , , cord-022526-j9kg00qf 1355 4 trefoil trefoil NN cord-022526-j9kg00qf 1355 5 peptides peptide NNS cord-022526-j9kg00qf 1355 6 have have VBP cord-022526-j9kg00qf 1355 7 the the DT cord-022526-j9kg00qf 1355 8 ability ability NN cord-022526-j9kg00qf 1355 9 to to TO cord-022526-j9kg00qf 1355 10 induce induce VB cord-022526-j9kg00qf 1355 11 their -PRON- PRP$ cord-022526-j9kg00qf 1355 12 own own JJ cord-022526-j9kg00qf 1355 13 expression expression NN cord-022526-j9kg00qf 1355 14 , , , cord-022526-j9kg00qf 1355 15 amplifying amplify VBG cord-022526-j9kg00qf 1355 16 the the DT cord-022526-j9kg00qf 1355 17 level level NN cord-022526-j9kg00qf 1355 18 of of IN cord-022526-j9kg00qf 1355 19 these these DT cord-022526-j9kg00qf 1355 20 reparative reparative JJ cord-022526-j9kg00qf 1355 21 factors factor NNS cord-022526-j9kg00qf 1355 22 at at IN cord-022526-j9kg00qf 1355 23 sites site NNS cord-022526-j9kg00qf 1355 24 of of IN cord-022526-j9kg00qf 1355 25 mucosal mucosal JJ cord-022526-j9kg00qf 1355 26 repair repair NN cord-022526-j9kg00qf 1355 27 . . . cord-022526-j9kg00qf 1356 1 127 127 CD cord-022526-j9kg00qf 1356 2 Trefoil Trefoil NNP cord-022526-j9kg00qf 1356 3 peptides peptide NNS cord-022526-j9kg00qf 1356 4 are be VBP cord-022526-j9kg00qf 1356 5 the the DT cord-022526-j9kg00qf 1356 6 most most RBS cord-022526-j9kg00qf 1356 7 potent potent JJ cord-022526-j9kg00qf 1356 8 stimulants stimulant NNS cord-022526-j9kg00qf 1356 9 of of IN cord-022526-j9kg00qf 1356 10 epithelial epithelial JJ cord-022526-j9kg00qf 1356 11 migration migration NN cord-022526-j9kg00qf 1356 12 in in IN cord-022526-j9kg00qf 1356 13 vitro vitro FW cord-022526-j9kg00qf 1356 14 , , , cord-022526-j9kg00qf 1356 15 and and CC cord-022526-j9kg00qf 1356 16 their -PRON- PRP$ cord-022526-j9kg00qf 1356 17 effects effect NNS cord-022526-j9kg00qf 1356 18 are be VBP cord-022526-j9kg00qf 1356 19 independent independent JJ cord-022526-j9kg00qf 1356 20 of of IN cord-022526-j9kg00qf 1356 21 growth growth NN cord-022526-j9kg00qf 1356 22 factors factor NNS cord-022526-j9kg00qf 1356 23 , , , cord-022526-j9kg00qf 1356 24 including include VBG cord-022526-j9kg00qf 1356 25 TGF TGF NNP cord-022526-j9kg00qf 1356 26 - - HYPH cord-022526-j9kg00qf 1356 27 β β NNP cord-022526-j9kg00qf 1356 28 . . . cord-022526-j9kg00qf 1357 1 128 128 CD cord-022526-j9kg00qf 1358 1 However however RB cord-022526-j9kg00qf 1358 2 , , , cord-022526-j9kg00qf 1358 3 recent recent JJ cord-022526-j9kg00qf 1358 4 evidence evidence NN cord-022526-j9kg00qf 1358 5 suggests suggest VBZ cord-022526-j9kg00qf 1358 6 that that IN cord-022526-j9kg00qf 1358 7 EGF EGF NNP cord-022526-j9kg00qf 1358 8 receptor receptor NN cord-022526-j9kg00qf 1358 9 activation activation NN cord-022526-j9kg00qf 1358 10 is be VBZ cord-022526-j9kg00qf 1358 11 required require VBN cord-022526-j9kg00qf 1358 12 for for IN cord-022526-j9kg00qf 1358 13 induction induction NN cord-022526-j9kg00qf 1358 14 of of IN cord-022526-j9kg00qf 1358 15 pS2 ps2 NN cord-022526-j9kg00qf 1358 16 and and CC cord-022526-j9kg00qf 1358 17 another another DT cord-022526-j9kg00qf 1358 18 of of IN cord-022526-j9kg00qf 1358 19 the the DT cord-022526-j9kg00qf 1358 20 trefoil trefoil NN cord-022526-j9kg00qf 1358 21 peptides peptide NNS cord-022526-j9kg00qf 1358 22 , , , cord-022526-j9kg00qf 1358 23 termed term VBD cord-022526-j9kg00qf 1358 24 spasmolytic spasmolytic JJ cord-022526-j9kg00qf 1358 25 peptide peptide NN cord-022526-j9kg00qf 1358 26 , , , cord-022526-j9kg00qf 1358 27 in in IN cord-022526-j9kg00qf 1358 28 gastric gastric JJ cord-022526-j9kg00qf 1358 29 epithelium epithelium NN cord-022526-j9kg00qf 1358 30 in in IN cord-022526-j9kg00qf 1358 31 vitro vitro FW cord-022526-j9kg00qf 1358 32 . . . cord-022526-j9kg00qf 1359 1 The the DT cord-022526-j9kg00qf 1359 2 importance importance NN cord-022526-j9kg00qf 1359 3 of of IN cord-022526-j9kg00qf 1359 4 trefoil trefoil NN cord-022526-j9kg00qf 1359 5 peptides peptide NNS cord-022526-j9kg00qf 1359 6 to to IN cord-022526-j9kg00qf 1359 7 the the DT cord-022526-j9kg00qf 1359 8 mucosal mucosal NN cord-022526-j9kg00qf 1359 9 repair repair NN cord-022526-j9kg00qf 1359 10 response response NN cord-022526-j9kg00qf 1359 11 in in IN cord-022526-j9kg00qf 1359 12 vivo vivo NNP cord-022526-j9kg00qf 1359 13 is be VBZ cord-022526-j9kg00qf 1359 14 illustrated illustrate VBN cord-022526-j9kg00qf 1359 15 by by IN cord-022526-j9kg00qf 1359 16 gene gene NN cord-022526-j9kg00qf 1359 17 knockout knockout NN cord-022526-j9kg00qf 1359 18 studies study NNS cord-022526-j9kg00qf 1359 19 , , , cord-022526-j9kg00qf 1359 20 in in IN cord-022526-j9kg00qf 1359 21 which which WDT cord-022526-j9kg00qf 1359 22 mice mouse NNS cord-022526-j9kg00qf 1359 23 deficient deficient JJ cord-022526-j9kg00qf 1359 24 in in IN cord-022526-j9kg00qf 1359 25 intestinal intestinal JJ cord-022526-j9kg00qf 1359 26 trefoil trefoil NN cord-022526-j9kg00qf 1359 27 factor factor NN cord-022526-j9kg00qf 1359 28 have have VBP cord-022526-j9kg00qf 1359 29 greatly greatly RB cord-022526-j9kg00qf 1359 30 reduced reduce VBN cord-022526-j9kg00qf 1359 31 ability ability NN cord-022526-j9kg00qf 1359 32 to to TO cord-022526-j9kg00qf 1359 33 repair repair VB cord-022526-j9kg00qf 1359 34 intestinal intestinal JJ cord-022526-j9kg00qf 1359 35 injury injury NN cord-022526-j9kg00qf 1359 36 . . . cord-022526-j9kg00qf 1360 1 129 129 CD cord-022526-j9kg00qf 1361 1 In in IN cord-022526-j9kg00qf 1361 2 fact fact NN cord-022526-j9kg00qf 1361 3 , , , cord-022526-j9kg00qf 1361 4 detergent detergent NN cord-022526-j9kg00qf 1361 5 - - HYPH cord-022526-j9kg00qf 1361 6 induced induce VBN cord-022526-j9kg00qf 1361 7 mucosal mucosal JJ cord-022526-j9kg00qf 1361 8 injury injury NN cord-022526-j9kg00qf 1361 9 was be VBD cord-022526-j9kg00qf 1361 10 lethal lethal JJ cord-022526-j9kg00qf 1361 11 because because IN cord-022526-j9kg00qf 1361 12 of of IN cord-022526-j9kg00qf 1361 13 a a DT cord-022526-j9kg00qf 1361 14 lack lack NN cord-022526-j9kg00qf 1361 15 of of IN cord-022526-j9kg00qf 1361 16 restitution restitution NN cord-022526-j9kg00qf 1361 17 compared compare VBN cord-022526-j9kg00qf 1361 18 with with IN cord-022526-j9kg00qf 1361 19 wild wild JJ cord-022526-j9kg00qf 1361 20 - - HYPH cord-022526-j9kg00qf 1361 21 type type NN cord-022526-j9kg00qf 1361 22 mice mouse NNS cord-022526-j9kg00qf 1361 23 that that WDT cord-022526-j9kg00qf 1361 24 fully fully RB cord-022526-j9kg00qf 1361 25 recovered recover VBD cord-022526-j9kg00qf 1361 26 from from IN cord-022526-j9kg00qf 1361 27 similar similar JJ cord-022526-j9kg00qf 1361 28 mucosal mucosal JJ cord-022526-j9kg00qf 1361 29 injury injury NN cord-022526-j9kg00qf 1361 30 . . . cord-022526-j9kg00qf 1362 1 The the DT cord-022526-j9kg00qf 1362 2 fact fact NN cord-022526-j9kg00qf 1362 3 that that IN cord-022526-j9kg00qf 1362 4 administration administration NN cord-022526-j9kg00qf 1362 5 of of IN cord-022526-j9kg00qf 1362 6 intestinal intestinal JJ cord-022526-j9kg00qf 1362 7 trefoil trefoil NN cord-022526-j9kg00qf 1362 8 factor factor NN cord-022526-j9kg00qf 1362 9 restored restore VBD cord-022526-j9kg00qf 1362 10 restitution restitution NN cord-022526-j9kg00qf 1362 11 has have VBZ cord-022526-j9kg00qf 1362 12 important important JJ cord-022526-j9kg00qf 1362 13 therapeutic therapeutic JJ cord-022526-j9kg00qf 1362 14 implications implication NNS cord-022526-j9kg00qf 1362 15 . . . cord-022526-j9kg00qf 1363 1 The the DT cord-022526-j9kg00qf 1363 2 mechanism mechanism NN cord-022526-j9kg00qf 1363 3 whereby whereby WRB cord-022526-j9kg00qf 1363 4 trefoil trefoil NN cord-022526-j9kg00qf 1363 5 peptides peptide NNS cord-022526-j9kg00qf 1363 6 stimulate stimulate VBP cord-022526-j9kg00qf 1363 7 epithelial epithelial JJ cord-022526-j9kg00qf 1363 8 migration migration NN cord-022526-j9kg00qf 1363 9 is be VBZ cord-022526-j9kg00qf 1363 10 yet yet RB cord-022526-j9kg00qf 1363 11 to to TO cord-022526-j9kg00qf 1363 12 be be VB cord-022526-j9kg00qf 1363 13 characterized characterize VBN cord-022526-j9kg00qf 1363 14 fully fully RB cord-022526-j9kg00qf 1363 15 but but CC cord-022526-j9kg00qf 1363 16 appears appear VBZ cord-022526-j9kg00qf 1363 17 to to TO cord-022526-j9kg00qf 1363 18 involve involve VB cord-022526-j9kg00qf 1363 19 translocation translocation NN cord-022526-j9kg00qf 1363 20 of of IN cord-022526-j9kg00qf 1363 21 the the DT cord-022526-j9kg00qf 1363 22 adherens adherens NNP cord-022526-j9kg00qf 1363 23 junction junction NN cord-022526-j9kg00qf 1363 24 protein protein NN cord-022526-j9kg00qf 1363 25 E e NN cord-022526-j9kg00qf 1363 26 - - NN cord-022526-j9kg00qf 1363 27 cadherin cadherin NN cord-022526-j9kg00qf 1363 28 , , , cord-022526-j9kg00qf 1363 29 thereby thereby RB cord-022526-j9kg00qf 1363 30 allowing allow VBG cord-022526-j9kg00qf 1363 31 cells cell NNS cord-022526-j9kg00qf 1363 32 to to TO cord-022526-j9kg00qf 1363 33 become become VB cord-022526-j9kg00qf 1363 34 untethered untethered JJ cord-022526-j9kg00qf 1363 35 from from IN cord-022526-j9kg00qf 1363 36 neighboring neighboring NN cord-022526-j9kg00qf 1363 37 cells cell NNS cord-022526-j9kg00qf 1363 38 . . . cord-022526-j9kg00qf 1364 1 26 26 CD cord-022526-j9kg00qf 1364 2 _SP cord-022526-j9kg00qf 1365 1 The the DT cord-022526-j9kg00qf 1365 2 principal principal JJ cord-022526-j9kg00qf 1365 3 metabolic metabolic JJ cord-022526-j9kg00qf 1365 4 fuel fuel NN cord-022526-j9kg00qf 1365 5 of of IN cord-022526-j9kg00qf 1365 6 enterocytes enterocyte NNS cord-022526-j9kg00qf 1365 7 is be VBZ cord-022526-j9kg00qf 1365 8 glutamine glutamine NN cord-022526-j9kg00qf 1365 9 and and CC cord-022526-j9kg00qf 1365 10 of of IN cord-022526-j9kg00qf 1365 11 colonocytes colonocyte NNS cord-022526-j9kg00qf 1365 12 , , , cord-022526-j9kg00qf 1365 13 butyrate butyrate NN cord-022526-j9kg00qf 1365 14 . . . cord-022526-j9kg00qf 1366 1 However however RB cord-022526-j9kg00qf 1366 2 , , , cord-022526-j9kg00qf 1366 3 recent recent JJ cord-022526-j9kg00qf 1366 4 studies study NNS cord-022526-j9kg00qf 1366 5 suggest suggest VBP cord-022526-j9kg00qf 1366 6 that that IN cord-022526-j9kg00qf 1366 7 glutamine glutamine NN cord-022526-j9kg00qf 1366 8 and and CC cord-022526-j9kg00qf 1366 9 butyrate butyrate NN cord-022526-j9kg00qf 1366 10 have have VBP cord-022526-j9kg00qf 1366 11 more more RBR cord-022526-j9kg00qf 1366 12 specific specific JJ cord-022526-j9kg00qf 1366 13 proliferative proliferative JJ cord-022526-j9kg00qf 1366 14 actions action NNS cord-022526-j9kg00qf 1366 15 aside aside RB cord-022526-j9kg00qf 1366 16 from from IN cord-022526-j9kg00qf 1366 17 their -PRON- PRP$ cord-022526-j9kg00qf 1366 18 role role NN cord-022526-j9kg00qf 1366 19 as as IN cord-022526-j9kg00qf 1366 20 nutrients nutrient NNS cord-022526-j9kg00qf 1366 21 . . . cord-022526-j9kg00qf 1367 1 For for IN cord-022526-j9kg00qf 1367 2 example example NN cord-022526-j9kg00qf 1367 3 , , , cord-022526-j9kg00qf 1367 4 in in IN cord-022526-j9kg00qf 1367 5 the the DT cord-022526-j9kg00qf 1367 6 piglet piglet NN cord-022526-j9kg00qf 1367 7 IPEC IPEC NNP cord-022526-j9kg00qf 1367 8 - - HYPH cord-022526-j9kg00qf 1367 9 J2 J2 NNP cord-022526-j9kg00qf 1367 10 enterocyte enterocyte NNP cord-022526-j9kg00qf 1367 11 cell cell NN cord-022526-j9kg00qf 1367 12 line line NN cord-022526-j9kg00qf 1367 13 , , , cord-022526-j9kg00qf 1367 14 glutamine glutamine NN cord-022526-j9kg00qf 1367 15 enhanced enhance VBN cord-022526-j9kg00qf 1367 16 gene gene NN cord-022526-j9kg00qf 1367 17 transcription transcription NN cord-022526-j9kg00qf 1367 18 by by IN cord-022526-j9kg00qf 1367 19 increasing increase VBG cord-022526-j9kg00qf 1367 20 mitogen mitogen NN cord-022526-j9kg00qf 1367 21 - - HYPH cord-022526-j9kg00qf 1367 22 activated activate VBN cord-022526-j9kg00qf 1367 23 protein protein NN cord-022526-j9kg00qf 1367 24 kinase kinase NN cord-022526-j9kg00qf 1367 25 activity activity NN cord-022526-j9kg00qf 1367 26 . . . cord-022526-j9kg00qf 1368 1 130 130 CD cord-022526-j9kg00qf 1368 2 , , , cord-022526-j9kg00qf 1368 3 131 131 CD cord-022526-j9kg00qf 1369 1 Similarly similarly RB cord-022526-j9kg00qf 1369 2 , , , cord-022526-j9kg00qf 1369 3 butyrate butyrate NN cord-022526-j9kg00qf 1369 4 stimulated stimulate VBD cord-022526-j9kg00qf 1369 5 mucosal mucosal JJ cord-022526-j9kg00qf 1369 6 growth growth NN cord-022526-j9kg00qf 1369 7 following follow VBG cord-022526-j9kg00qf 1369 8 colonic colonic JJ cord-022526-j9kg00qf 1369 9 infusion infusion NN cord-022526-j9kg00qf 1369 10 in in IN cord-022526-j9kg00qf 1369 11 the the DT cord-022526-j9kg00qf 1369 12 rat rat NN cord-022526-j9kg00qf 1369 13 . . . cord-022526-j9kg00qf 1370 1 132 132 CD cord-022526-j9kg00qf 1371 1 Because because IN cord-022526-j9kg00qf 1371 2 of of IN cord-022526-j9kg00qf 1371 3 such such JJ cord-022526-j9kg00qf 1371 4 growth growth NN cord-022526-j9kg00qf 1371 5 - - HYPH cord-022526-j9kg00qf 1371 6 promoting promote VBG cord-022526-j9kg00qf 1371 7 actions action NNS cord-022526-j9kg00qf 1371 8 , , , cord-022526-j9kg00qf 1371 9 glutamine glutamine NN cord-022526-j9kg00qf 1371 10 was be VBD cord-022526-j9kg00qf 1371 11 shown show VBN cord-022526-j9kg00qf 1371 12 to to TO cord-022526-j9kg00qf 1371 13 prevent prevent VB cord-022526-j9kg00qf 1371 14 intestinal intestinal JJ cord-022526-j9kg00qf 1371 15 mucosal mucosal JJ cord-022526-j9kg00qf 1371 16 atrophy atrophy NN cord-022526-j9kg00qf 1371 17 and and CC cord-022526-j9kg00qf 1371 18 dysfunction dysfunction NN cord-022526-j9kg00qf 1371 19 that that WDT cord-022526-j9kg00qf 1371 20 accompanies accompany VBZ cord-022526-j9kg00qf 1371 21 starvation starvation NN cord-022526-j9kg00qf 1371 22 133 133 CD cord-022526-j9kg00qf 1371 23 , , , cord-022526-j9kg00qf 1371 24 134 134 CD cord-022526-j9kg00qf 1371 25 and and CC cord-022526-j9kg00qf 1371 26 long long JJ cord-022526-j9kg00qf 1371 27 - - HYPH cord-022526-j9kg00qf 1371 28 term term NN cord-022526-j9kg00qf 1371 29 total total JJ cord-022526-j9kg00qf 1371 30 parental parental JJ cord-022526-j9kg00qf 1371 31 nutrition nutrition NN cord-022526-j9kg00qf 1371 32 . . . cord-022526-j9kg00qf 1372 1 135 135 CD cord-022526-j9kg00qf 1372 2 , , , cord-022526-j9kg00qf 1372 3 136 136 CD cord-022526-j9kg00qf 1372 4 Additionally additionally RB cord-022526-j9kg00qf 1372 5 , , , cord-022526-j9kg00qf 1372 6 glutamine glutamine NN cord-022526-j9kg00qf 1372 7 improves improve VBZ cord-022526-j9kg00qf 1372 8 function function NN cord-022526-j9kg00qf 1372 9 of of IN cord-022526-j9kg00qf 1372 10 transplanted transplant VBN cord-022526-j9kg00qf 1372 11 small small JJ cord-022526-j9kg00qf 1372 12 intestine intestine NN cord-022526-j9kg00qf 1372 13 137 137 CD cord-022526-j9kg00qf 1372 14 , , , cord-022526-j9kg00qf 1372 15 138 138 CD cord-022526-j9kg00qf 1372 16 and and CC cord-022526-j9kg00qf 1372 17 protects protect VBZ cord-022526-j9kg00qf 1372 18 intestinal intestinal JJ cord-022526-j9kg00qf 1372 19 mucosa mucosa NN cord-022526-j9kg00qf 1372 20 from from IN cord-022526-j9kg00qf 1372 21 injury injury NN cord-022526-j9kg00qf 1372 22 if if IN cord-022526-j9kg00qf 1372 23 administered administer VBN cord-022526-j9kg00qf 1372 24 before before IN cord-022526-j9kg00qf 1372 25 chemotherapy chemotherapy NN cord-022526-j9kg00qf 1372 26 139 139 CD cord-022526-j9kg00qf 1372 27 and and CC cord-022526-j9kg00qf 1372 28 radiation radiation NN cord-022526-j9kg00qf 1372 29 therapy therapy NN cord-022526-j9kg00qf 1372 30 . . . cord-022526-j9kg00qf 1373 1 140 140 CD cord-022526-j9kg00qf 1373 2 , , , cord-022526-j9kg00qf 1373 3 141 141 CD cord-022526-j9kg00qf 1373 4 Intestinal intestinal JJ cord-022526-j9kg00qf 1373 5 nutrients nutrient NNS cord-022526-j9kg00qf 1373 6 also also RB cord-022526-j9kg00qf 1373 7 may may MD cord-022526-j9kg00qf 1373 8 synergize synergize VB cord-022526-j9kg00qf 1373 9 with with IN cord-022526-j9kg00qf 1373 10 other other JJ cord-022526-j9kg00qf 1373 11 proliferative proliferative JJ cord-022526-j9kg00qf 1373 12 agents agent NNS cord-022526-j9kg00qf 1373 13 . . . cord-022526-j9kg00qf 1374 1 For for IN cord-022526-j9kg00qf 1374 2 example example NN cord-022526-j9kg00qf 1374 3 , , , cord-022526-j9kg00qf 1374 4 administration administration NN cord-022526-j9kg00qf 1374 5 of of IN cord-022526-j9kg00qf 1374 6 glutamine glutamine NNP cord-022526-j9kg00qf 1374 7 and and CC cord-022526-j9kg00qf 1374 8 TGF TGF NNP cord-022526-j9kg00qf 1374 9 - - HYPH cord-022526-j9kg00qf 1374 10 α α NN cord-022526-j9kg00qf 1374 11 to to IN cord-022526-j9kg00qf 1374 12 porcine porcine JJ cord-022526-j9kg00qf 1374 13 ileum ileum NN cord-022526-j9kg00qf 1374 14 that that WDT cord-022526-j9kg00qf 1374 15 had have VBD cord-022526-j9kg00qf 1374 16 been be VBN cord-022526-j9kg00qf 1374 17 subjected subject VBN cord-022526-j9kg00qf 1374 18 to to IN cord-022526-j9kg00qf 1374 19 2 2 CD cord-022526-j9kg00qf 1374 20 hours hour NNS cord-022526-j9kg00qf 1374 21 of of IN cord-022526-j9kg00qf 1374 22 ischemia ischemia NN cord-022526-j9kg00qf 1374 23 resulted result VBD cord-022526-j9kg00qf 1374 24 in in IN cord-022526-j9kg00qf 1374 25 a a DT cord-022526-j9kg00qf 1374 26 synergistic synergistic JJ cord-022526-j9kg00qf 1374 27 increase increase NN cord-022526-j9kg00qf 1374 28 in in IN cord-022526-j9kg00qf 1374 29 mitogen mitogen NN cord-022526-j9kg00qf 1374 30 - - HYPH cord-022526-j9kg00qf 1374 31 activated activate VBN cord-022526-j9kg00qf 1374 32 protein protein NN cord-022526-j9kg00qf 1374 33 kinase kinase NN cord-022526-j9kg00qf 1374 34 activity activity NN cord-022526-j9kg00qf 1374 35 , , , cord-022526-j9kg00qf 1374 36 enterocyte enterocyte NN cord-022526-j9kg00qf 1374 37 proliferation proliferation NN cord-022526-j9kg00qf 1374 38 , , , cord-022526-j9kg00qf 1374 39 and and CC cord-022526-j9kg00qf 1374 40 villous villous NNP cord-022526-j9kg00qf 1374 41 surface surface NNP cord-022526-j9kg00qf 1374 42 area area NN cord-022526-j9kg00qf 1374 43 . . . cord-022526-j9kg00qf 1375 1 42 42 CD cord-022526-j9kg00qf 1376 1 Although although IN cord-022526-j9kg00qf 1376 2 concern concern NN cord-022526-j9kg00qf 1376 3 has have VBZ cord-022526-j9kg00qf 1376 4 arisen arise VBN cord-022526-j9kg00qf 1376 5 that that IN cord-022526-j9kg00qf 1376 6 such such JJ cord-022526-j9kg00qf 1376 7 early early JJ cord-022526-j9kg00qf 1376 8 return return NN cord-022526-j9kg00qf 1376 9 to to IN cord-022526-j9kg00qf 1376 10 normal normal JJ cord-022526-j9kg00qf 1376 11 surface surface NN cord-022526-j9kg00qf 1376 12 area area NN cord-022526-j9kg00qf 1376 13 may may MD cord-022526-j9kg00qf 1376 14 result result VB cord-022526-j9kg00qf 1376 15 in in IN cord-022526-j9kg00qf 1376 16 dysfunctional dysfunctional JJ cord-022526-j9kg00qf 1376 17 mucosal mucosal JJ cord-022526-j9kg00qf 1376 18 digestive digestive JJ cord-022526-j9kg00qf 1376 19 and and CC cord-022526-j9kg00qf 1376 20 absorptive absorptive JJ cord-022526-j9kg00qf 1376 21 function function NN cord-022526-j9kg00qf 1376 22 because because IN cord-022526-j9kg00qf 1376 23 of of IN cord-022526-j9kg00qf 1376 24 resurfacing resurface VBG cord-022526-j9kg00qf 1376 25 denuded denude VBN cord-022526-j9kg00qf 1376 26 mucosa mucosa NN cord-022526-j9kg00qf 1376 27 with with IN cord-022526-j9kg00qf 1376 28 immature immature JJ cord-022526-j9kg00qf 1376 29 epithelium epithelium NN cord-022526-j9kg00qf 1376 30 , , , cord-022526-j9kg00qf 1376 31 nutrients nutrient NNS cord-022526-j9kg00qf 1376 32 and and CC cord-022526-j9kg00qf 1376 33 growth growth NN cord-022526-j9kg00qf 1376 34 factors factor NNS cord-022526-j9kg00qf 1376 35 also also RB cord-022526-j9kg00qf 1376 36 appear appear VBP cord-022526-j9kg00qf 1376 37 to to TO cord-022526-j9kg00qf 1376 38 promote promote VB cord-022526-j9kg00qf 1376 39 early early JJ cord-022526-j9kg00qf 1376 40 differentiation differentiation NN cord-022526-j9kg00qf 1376 41 . . . cord-022526-j9kg00qf 1377 1 In in IN cord-022526-j9kg00qf 1377 2 the the DT cord-022526-j9kg00qf 1377 3 case case NN cord-022526-j9kg00qf 1377 4 of of IN cord-022526-j9kg00qf 1377 5 glutamine glutamine NN cord-022526-j9kg00qf 1377 6 and and CC cord-022526-j9kg00qf 1377 7 TGF TGF NNP cord-022526-j9kg00qf 1377 8 - - HYPH cord-022526-j9kg00qf 1377 9 α α NN cord-022526-j9kg00qf 1377 10 restoration restoration NN cord-022526-j9kg00qf 1377 11 of of IN cord-022526-j9kg00qf 1377 12 postischemic postischemic JJ cord-022526-j9kg00qf 1377 13 small small JJ cord-022526-j9kg00qf 1377 14 intestine intestine NN cord-022526-j9kg00qf 1377 15 , , , cord-022526-j9kg00qf 1377 16 rapid rapid JJ cord-022526-j9kg00qf 1377 17 recovery recovery NN cord-022526-j9kg00qf 1377 18 of of IN cord-022526-j9kg00qf 1377 19 digestive digestive JJ cord-022526-j9kg00qf 1377 20 enzymes enzyme NNS cord-022526-j9kg00qf 1377 21 also also RB cord-022526-j9kg00qf 1377 22 was be VBD cord-022526-j9kg00qf 1377 23 documented document VBN cord-022526-j9kg00qf 1377 24 . . . cord-022526-j9kg00qf 1378 1 142 142 CD cord-022526-j9kg00qf 1378 2 _SP cord-022526-j9kg00qf 1378 3 Effective effective JJ cord-022526-j9kg00qf 1378 4 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1378 5 motility motility NN cord-022526-j9kg00qf 1378 6 involves involve VBZ cord-022526-j9kg00qf 1378 7 a a DT cord-022526-j9kg00qf 1378 8 complex complex JJ cord-022526-j9kg00qf 1378 9 interaction interaction NN cord-022526-j9kg00qf 1378 10 between between IN cord-022526-j9kg00qf 1378 11 the the DT cord-022526-j9kg00qf 1378 12 enteric enteric JJ cord-022526-j9kg00qf 1378 13 nervous nervous JJ cord-022526-j9kg00qf 1378 14 system system NN cord-022526-j9kg00qf 1378 15 , , , cord-022526-j9kg00qf 1378 16 muscular muscular JJ cord-022526-j9kg00qf 1378 17 wall wall NN cord-022526-j9kg00qf 1378 18 , , , cord-022526-j9kg00qf 1378 19 and and CC cord-022526-j9kg00qf 1378 20 luminal luminal JJ cord-022526-j9kg00qf 1378 21 contents content NNS cord-022526-j9kg00qf 1378 22 . . . cord-022526-j9kg00qf 1379 1 Additional additional JJ cord-022526-j9kg00qf 1379 2 factors factor NNS cord-022526-j9kg00qf 1379 3 that that WDT cord-022526-j9kg00qf 1379 4 influence influence VBP cord-022526-j9kg00qf 1379 5 the the DT cord-022526-j9kg00qf 1379 6 net net JJ cord-022526-j9kg00qf 1379 7 transit transit NN cord-022526-j9kg00qf 1379 8 of of IN cord-022526-j9kg00qf 1379 9 digesta digesta NNS cord-022526-j9kg00qf 1379 10 include include VBP cord-022526-j9kg00qf 1379 11 gravity gravity NN cord-022526-j9kg00qf 1379 12 , , , cord-022526-j9kg00qf 1379 13 the the DT cord-022526-j9kg00qf 1379 14 volume volume NN cord-022526-j9kg00qf 1379 15 and and CC cord-022526-j9kg00qf 1379 16 viscosity viscosity NN cord-022526-j9kg00qf 1379 17 of of IN cord-022526-j9kg00qf 1379 18 the the DT cord-022526-j9kg00qf 1379 19 contents content NNS cord-022526-j9kg00qf 1379 20 , , , cord-022526-j9kg00qf 1379 21 and and CC cord-022526-j9kg00qf 1379 22 pressure pressure NN cord-022526-j9kg00qf 1379 23 gradients gradient NNS cord-022526-j9kg00qf 1379 24 created create VBN cord-022526-j9kg00qf 1379 25 by by IN cord-022526-j9kg00qf 1379 26 simultaneous simultaneous JJ cord-022526-j9kg00qf 1379 27 contraction contraction NN cord-022526-j9kg00qf 1379 28 and and CC cord-022526-j9kg00qf 1379 29 relaxation relaxation NN cord-022526-j9kg00qf 1379 30 of of IN cord-022526-j9kg00qf 1379 31 adjacent adjacent JJ cord-022526-j9kg00qf 1379 32 segments segment NNS cord-022526-j9kg00qf 1379 33 of of IN cord-022526-j9kg00qf 1379 34 bowel bowel NN cord-022526-j9kg00qf 1379 35 . . . cord-022526-j9kg00qf 1380 1 Casual casual JJ cord-022526-j9kg00qf 1380 2 use use NN cord-022526-j9kg00qf 1380 3 of of IN cord-022526-j9kg00qf 1380 4 the the DT cord-022526-j9kg00qf 1380 5 term term NN cord-022526-j9kg00qf 1380 6 intestinal intestinal JJ cord-022526-j9kg00qf 1380 7 motility motility NN cord-022526-j9kg00qf 1380 8 in in IN cord-022526-j9kg00qf 1380 9 veterinary veterinary JJ cord-022526-j9kg00qf 1380 10 medicine medicine NN cord-022526-j9kg00qf 1380 11 often often RB cord-022526-j9kg00qf 1380 12 underestimates underestimate VBZ cord-022526-j9kg00qf 1380 13 the the DT cord-022526-j9kg00qf 1380 14 complexity complexity NN cord-022526-j9kg00qf 1380 15 of of IN cord-022526-j9kg00qf 1380 16 the the DT cord-022526-j9kg00qf 1380 17 processes process NNS cord-022526-j9kg00qf 1380 18 involved involve VBN cord-022526-j9kg00qf 1380 19 in in IN cord-022526-j9kg00qf 1380 20 the the DT cord-022526-j9kg00qf 1380 21 transit transit NN cord-022526-j9kg00qf 1380 22 of of IN cord-022526-j9kg00qf 1380 23 intestinal intestinal JJ cord-022526-j9kg00qf 1380 24 contents content NNS cord-022526-j9kg00qf 1380 25 . . . cord-022526-j9kg00qf 1381 1 This this DT cord-022526-j9kg00qf 1381 2 is be VBZ cord-022526-j9kg00qf 1381 3 particularly particularly RB cord-022526-j9kg00qf 1381 4 true true JJ cord-022526-j9kg00qf 1381 5 when when WRB cord-022526-j9kg00qf 1381 6 the the DT cord-022526-j9kg00qf 1381 7 term term NN cord-022526-j9kg00qf 1381 8 is be VBZ cord-022526-j9kg00qf 1381 9 used use VBN cord-022526-j9kg00qf 1381 10 to to TO cord-022526-j9kg00qf 1381 11 describe describe VB cord-022526-j9kg00qf 1381 12 the the DT cord-022526-j9kg00qf 1381 13 frequency frequency NN cord-022526-j9kg00qf 1381 14 and and CC cord-022526-j9kg00qf 1381 15 or or CC cord-022526-j9kg00qf 1381 16 intensity intensity NN cord-022526-j9kg00qf 1381 17 of of IN cord-022526-j9kg00qf 1381 18 intestinal intestinal JJ cord-022526-j9kg00qf 1381 19 sounds sound NNS cord-022526-j9kg00qf 1381 20 , , , cord-022526-j9kg00qf 1381 21 or or CC cord-022526-j9kg00qf 1381 22 borborygmi borborygmi NN cord-022526-j9kg00qf 1381 23 . . . cord-022526-j9kg00qf 1382 1 The the DT cord-022526-j9kg00qf 1382 2 existence existence NN cord-022526-j9kg00qf 1382 3 of of IN cord-022526-j9kg00qf 1382 4 borborygmi borborygmi NN cord-022526-j9kg00qf 1382 5 does do VBZ cord-022526-j9kg00qf 1382 6 not not RB cord-022526-j9kg00qf 1382 7 always always RB cord-022526-j9kg00qf 1382 8 equate equate VB cord-022526-j9kg00qf 1382 9 with with IN cord-022526-j9kg00qf 1382 10 progressive progressive JJ cord-022526-j9kg00qf 1382 11 movement movement NN cord-022526-j9kg00qf 1382 12 of of IN cord-022526-j9kg00qf 1382 13 intestinal intestinal JJ cord-022526-j9kg00qf 1382 14 contents content NNS cord-022526-j9kg00qf 1382 15 . . . cord-022526-j9kg00qf 1383 1 Disruption disruption NN cord-022526-j9kg00qf 1383 2 to to IN cord-022526-j9kg00qf 1383 3 normal normal JJ cord-022526-j9kg00qf 1383 4 motility motility NN cord-022526-j9kg00qf 1383 5 occurs occur VBZ cord-022526-j9kg00qf 1383 6 commonly commonly RB cord-022526-j9kg00qf 1383 7 in in IN cord-022526-j9kg00qf 1383 8 horses horse NNS cord-022526-j9kg00qf 1383 9 for for IN cord-022526-j9kg00qf 1383 10 a a DT cord-022526-j9kg00qf 1383 11 variety variety NN cord-022526-j9kg00qf 1383 12 of of IN cord-022526-j9kg00qf 1383 13 reasons reason NNS cord-022526-j9kg00qf 1383 14 . . . cord-022526-j9kg00qf 1384 1 Examples example NNS cord-022526-j9kg00qf 1384 2 of of IN cord-022526-j9kg00qf 1384 3 diseases disease NNS cord-022526-j9kg00qf 1384 4 in in IN cord-022526-j9kg00qf 1384 5 which which WDT cord-022526-j9kg00qf 1384 6 altered alter VBD cord-022526-j9kg00qf 1384 7 motility motility NN cord-022526-j9kg00qf 1384 8 may may MD cord-022526-j9kg00qf 1384 9 be be VB cord-022526-j9kg00qf 1384 10 present present JJ cord-022526-j9kg00qf 1384 11 include include VBP cord-022526-j9kg00qf 1384 12 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 1384 13 ulceration ulceration NN cord-022526-j9kg00qf 1384 14 , , , cord-022526-j9kg00qf 1384 15 intraluminal intraluminal JJ cord-022526-j9kg00qf 1384 16 obstruction obstruction NN cord-022526-j9kg00qf 1384 17 or or CC cord-022526-j9kg00qf 1384 18 impaction impaction NN cord-022526-j9kg00qf 1384 19 , , , cord-022526-j9kg00qf 1384 20 excessive excessive JJ cord-022526-j9kg00qf 1384 21 wall wall NN cord-022526-j9kg00qf 1384 22 distention distention NN cord-022526-j9kg00qf 1384 23 , , , cord-022526-j9kg00qf 1384 24 strangulating strangulate VBG cord-022526-j9kg00qf 1384 25 obstructions obstruction NNS cord-022526-j9kg00qf 1384 26 , , , cord-022526-j9kg00qf 1384 27 peritonitis peritonitis NN cord-022526-j9kg00qf 1384 28 , , , cord-022526-j9kg00qf 1384 29 and and CC cord-022526-j9kg00qf 1384 30 inflammatory inflammatory JJ cord-022526-j9kg00qf 1384 31 bowel bowel NN cord-022526-j9kg00qf 1384 32 diseases disease NNS cord-022526-j9kg00qf 1384 33 such such JJ cord-022526-j9kg00qf 1384 34 as as IN cord-022526-j9kg00qf 1384 35 duodenitis duodenitis NNP cord-022526-j9kg00qf 1384 36 proximal proximal JJ cord-022526-j9kg00qf 1384 37 jejunits jejunit NNS cord-022526-j9kg00qf 1384 38 or or CC cord-022526-j9kg00qf 1384 39 colitis colitis NN cord-022526-j9kg00qf 1384 40 . . . cord-022526-j9kg00qf 1385 1 Ineffective ineffective JJ cord-022526-j9kg00qf 1385 2 intestinal intestinal JJ cord-022526-j9kg00qf 1385 3 motility motility NN cord-022526-j9kg00qf 1385 4 is be VBZ cord-022526-j9kg00qf 1385 5 also also RB cord-022526-j9kg00qf 1385 6 a a DT cord-022526-j9kg00qf 1385 7 feature feature NN cord-022526-j9kg00qf 1385 8 of of IN cord-022526-j9kg00qf 1385 9 several several JJ cord-022526-j9kg00qf 1385 10 neonatal neonatal JJ cord-022526-j9kg00qf 1385 11 diseases disease NNS cord-022526-j9kg00qf 1385 12 , , , cord-022526-j9kg00qf 1385 13 including include VBG cord-022526-j9kg00qf 1385 14 prematurity prematurity NN cord-022526-j9kg00qf 1385 15 , , , cord-022526-j9kg00qf 1385 16 systemic systemic JJ cord-022526-j9kg00qf 1385 17 sepsis sepsis NN cord-022526-j9kg00qf 1385 18 , , , cord-022526-j9kg00qf 1385 19 and and CC cord-022526-j9kg00qf 1385 20 perinatal perinatal JJ cord-022526-j9kg00qf 1385 21 asphyxia asphyxia NN cord-022526-j9kg00qf 1385 22 . . . cord-022526-j9kg00qf 1386 1 Certain certain JJ cord-022526-j9kg00qf 1386 2 parasitic parasitic JJ cord-022526-j9kg00qf 1386 3 infections infection NNS cord-022526-j9kg00qf 1386 4 , , , cord-022526-j9kg00qf 1386 5 electrolyte electrolyte JJ cord-022526-j9kg00qf 1386 6 derangements derangement NNS cord-022526-j9kg00qf 1386 7 , , , cord-022526-j9kg00qf 1386 8 and and CC cord-022526-j9kg00qf 1386 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1386 10 can can MD cord-022526-j9kg00qf 1386 11 modify modify VB cord-022526-j9kg00qf 1386 12 digesta digesta JJ cord-022526-j9kg00qf 1386 13 transit transit NN cord-022526-j9kg00qf 1386 14 in in IN cord-022526-j9kg00qf 1386 15 horses horse NNS cord-022526-j9kg00qf 1386 16 of of IN cord-022526-j9kg00qf 1386 17 all all DT cord-022526-j9kg00qf 1386 18 ages age NNS cord-022526-j9kg00qf 1386 19 . . . cord-022526-j9kg00qf 1387 1 General general JJ cord-022526-j9kg00qf 1387 2 anesthesia anesthesia NN cord-022526-j9kg00qf 1387 3 and and CC cord-022526-j9kg00qf 1387 4 specific specific JJ cord-022526-j9kg00qf 1387 5 sedatives sedative NNS cord-022526-j9kg00qf 1387 6 , , , cord-022526-j9kg00qf 1387 7 such such JJ cord-022526-j9kg00qf 1387 8 as as IN cord-022526-j9kg00qf 1387 9 xylazine xylazine NNP cord-022526-j9kg00qf 1387 10 , , , cord-022526-j9kg00qf 1387 11 romifidine romifidine NN cord-022526-j9kg00qf 1387 12 , , , cord-022526-j9kg00qf 1387 13 or or CC cord-022526-j9kg00qf 1387 14 detomidine detomidine NN cord-022526-j9kg00qf 1387 15 , , , cord-022526-j9kg00qf 1387 16 also also RB cord-022526-j9kg00qf 1387 17 disturb disturb VB cord-022526-j9kg00qf 1387 18 motility motility NN cord-022526-j9kg00qf 1387 19 . . . cord-022526-j9kg00qf 1388 1 The the DT cord-022526-j9kg00qf 1388 2 inhibition inhibition NN cord-022526-j9kg00qf 1388 3 of of IN cord-022526-j9kg00qf 1388 4 propulsive propulsive JJ cord-022526-j9kg00qf 1388 5 bowel bowel NN cord-022526-j9kg00qf 1388 6 activity activity NN cord-022526-j9kg00qf 1388 7 usually usually RB cord-022526-j9kg00qf 1388 8 is be VBZ cord-022526-j9kg00qf 1388 9 referred refer VBN cord-022526-j9kg00qf 1388 10 to to IN cord-022526-j9kg00qf 1388 11 as as IN cord-022526-j9kg00qf 1388 12 ileus ileus NNP cord-022526-j9kg00qf 1388 13 . . . cord-022526-j9kg00qf 1389 1 Ileus Ileus NNP cord-022526-j9kg00qf 1389 2 is be VBZ cord-022526-j9kg00qf 1389 3 ascribed ascribe VBN cord-022526-j9kg00qf 1389 4 most most RBS cord-022526-j9kg00qf 1389 5 frequently frequently RB cord-022526-j9kg00qf 1389 6 to to IN cord-022526-j9kg00qf 1389 7 the the DT cord-022526-j9kg00qf 1389 8 condition condition NN cord-022526-j9kg00qf 1389 9 that that WDT cord-022526-j9kg00qf 1389 10 occurs occur VBZ cord-022526-j9kg00qf 1389 11 after after IN cord-022526-j9kg00qf 1389 12 laparotomy laparotomy NN cord-022526-j9kg00qf 1389 13 and and CC cord-022526-j9kg00qf 1389 14 is be VBZ cord-022526-j9kg00qf 1389 15 termed term VBN cord-022526-j9kg00qf 1389 16 simple simple JJ cord-022526-j9kg00qf 1389 17 or or CC cord-022526-j9kg00qf 1389 18 uncomplicated uncomplicated JJ cord-022526-j9kg00qf 1389 19 postoperative postoperative JJ cord-022526-j9kg00qf 1389 20 ileus ileus NN cord-022526-j9kg00qf 1389 21 ( ( -LRB- cord-022526-j9kg00qf 1389 22 POI POI NNP cord-022526-j9kg00qf 1389 23 ) ) -RRB- cord-022526-j9kg00qf 1389 24 . . . cord-022526-j9kg00qf 1390 1 The the DT cord-022526-j9kg00qf 1390 2 term term NN cord-022526-j9kg00qf 1390 3 complicated complicated JJ cord-022526-j9kg00qf 1390 4 or or CC cord-022526-j9kg00qf 1390 5 paralytic paralytic JJ cord-022526-j9kg00qf 1390 6 ileus ileus NN cord-022526-j9kg00qf 1390 7 describes describe VBZ cord-022526-j9kg00qf 1390 8 intestinal intestinal JJ cord-022526-j9kg00qf 1390 9 motility motility NN cord-022526-j9kg00qf 1390 10 disturbed disturb VBN cord-022526-j9kg00qf 1390 11 for for IN cord-022526-j9kg00qf 1390 12 longer long JJR cord-022526-j9kg00qf 1390 13 periods period NNS cord-022526-j9kg00qf 1390 14 after after IN cord-022526-j9kg00qf 1390 15 surgery surgery NN cord-022526-j9kg00qf 1390 16 . . . cord-022526-j9kg00qf 1391 1 POI POI NNP cord-022526-j9kg00qf 1391 2 in in IN cord-022526-j9kg00qf 1391 3 horses horse NNS cord-022526-j9kg00qf 1391 4 is be VBZ cord-022526-j9kg00qf 1391 5 associated associate VBN cord-022526-j9kg00qf 1391 6 most most RBS cord-022526-j9kg00qf 1391 7 commonly commonly RB cord-022526-j9kg00qf 1391 8 with with IN cord-022526-j9kg00qf 1391 9 surgery surgery NN cord-022526-j9kg00qf 1391 10 of of IN cord-022526-j9kg00qf 1391 11 the the DT cord-022526-j9kg00qf 1391 12 small small JJ cord-022526-j9kg00qf 1391 13 intestine intestine NN cord-022526-j9kg00qf 1391 14 , , , cord-022526-j9kg00qf 1391 15 particularly particularly RB cord-022526-j9kg00qf 1391 16 after after IN cord-022526-j9kg00qf 1391 17 resection resection NN cord-022526-j9kg00qf 1391 18 and and CC cord-022526-j9kg00qf 1391 19 anastomosis anastomosis NN cord-022526-j9kg00qf 1391 20 , , , cord-022526-j9kg00qf 1391 21 1,2 1,2 CD cord-022526-j9kg00qf 1391 22 is be VBZ cord-022526-j9kg00qf 1391 23 a a DT cord-022526-j9kg00qf 1391 24 common common JJ cord-022526-j9kg00qf 1391 25 complication complication NN cord-022526-j9kg00qf 1391 26 of of IN cord-022526-j9kg00qf 1391 27 small small JJ cord-022526-j9kg00qf 1391 28 intestinal intestinal JJ cord-022526-j9kg00qf 1391 29 surgery surgery NN cord-022526-j9kg00qf 1391 30 , , , cord-022526-j9kg00qf 1391 31 and and CC cord-022526-j9kg00qf 1391 32 can can MD cord-022526-j9kg00qf 1391 33 have have VB cord-022526-j9kg00qf 1391 34 a a DT cord-022526-j9kg00qf 1391 35 negative negative JJ cord-022526-j9kg00qf 1391 36 effect effect NN cord-022526-j9kg00qf 1391 37 on on IN cord-022526-j9kg00qf 1391 38 short short JJ cord-022526-j9kg00qf 1391 39 - - HYPH cord-022526-j9kg00qf 1391 40 term term NN cord-022526-j9kg00qf 1391 41 postoperative postoperative JJ cord-022526-j9kg00qf 1391 42 survival survival NN cord-022526-j9kg00qf 1391 43 . . . cord-022526-j9kg00qf 1392 1 3 3 CD cord-022526-j9kg00qf 1392 2 , , , cord-022526-j9kg00qf 1392 3 4 4 CD cord-022526-j9kg00qf 1392 4 Motility Motility NNP cord-022526-j9kg00qf 1392 5 dysfunction dysfunction NN cord-022526-j9kg00qf 1392 6 likely likely RB cord-022526-j9kg00qf 1392 7 is be VBZ cord-022526-j9kg00qf 1392 8 present present JJ cord-022526-j9kg00qf 1392 9 in in IN cord-022526-j9kg00qf 1392 10 all all DT cord-022526-j9kg00qf 1392 11 horses horse NNS cord-022526-j9kg00qf 1392 12 after after IN cord-022526-j9kg00qf 1392 13 laparotomy laparotomy NN cord-022526-j9kg00qf 1392 14 , , , cord-022526-j9kg00qf 1392 15 but but CC cord-022526-j9kg00qf 1392 16 many many JJ cord-022526-j9kg00qf 1392 17 are be VBP cord-022526-j9kg00qf 1392 18 affected affect VBN cord-022526-j9kg00qf 1392 19 subclinically subclinically RB cord-022526-j9kg00qf 1392 20 and and CC cord-022526-j9kg00qf 1392 21 require require VBP cord-022526-j9kg00qf 1392 22 minimal minimal JJ cord-022526-j9kg00qf 1392 23 or or CC cord-022526-j9kg00qf 1392 24 no no DT cord-022526-j9kg00qf 1392 25 specific specific JJ cord-022526-j9kg00qf 1392 26 intervention intervention NN cord-022526-j9kg00qf 1392 27 . . . cord-022526-j9kg00qf 1393 1 In in IN cord-022526-j9kg00qf 1393 2 symptomatic symptomatic JJ cord-022526-j9kg00qf 1393 3 animals animal NNS cord-022526-j9kg00qf 1393 4 , , , cord-022526-j9kg00qf 1393 5 clinical clinical JJ cord-022526-j9kg00qf 1393 6 signs sign NNS cord-022526-j9kg00qf 1393 7 are be VBP cord-022526-j9kg00qf 1393 8 apparent apparent JJ cord-022526-j9kg00qf 1393 9 shortly shortly RB cord-022526-j9kg00qf 1393 10 after after IN cord-022526-j9kg00qf 1393 11 recovery recovery NN cord-022526-j9kg00qf 1393 12 and and CC cord-022526-j9kg00qf 1393 13 include include VBP cord-022526-j9kg00qf 1393 14 colic colic NN cord-022526-j9kg00qf 1393 15 , , , cord-022526-j9kg00qf 1393 16 tachycardia tachycardia NN cord-022526-j9kg00qf 1393 17 , , , cord-022526-j9kg00qf 1393 18 dehydration dehydration NN cord-022526-j9kg00qf 1393 19 , , , cord-022526-j9kg00qf 1393 20 decreased decrease VBD cord-022526-j9kg00qf 1393 21 borborygmi borborygmi NN cord-022526-j9kg00qf 1393 22 and and CC cord-022526-j9kg00qf 1393 23 fecal fecal JJ cord-022526-j9kg00qf 1393 24 output output NN cord-022526-j9kg00qf 1393 25 , , , cord-022526-j9kg00qf 1393 26 and and CC cord-022526-j9kg00qf 1393 27 sequestration sequestration NN cord-022526-j9kg00qf 1393 28 of of IN cord-022526-j9kg00qf 1393 29 fluid fluid NN cord-022526-j9kg00qf 1393 30 within within IN cord-022526-j9kg00qf 1393 31 the the DT cord-022526-j9kg00qf 1393 32 stomach stomach NN cord-022526-j9kg00qf 1393 33 . . . cord-022526-j9kg00qf 1394 1 Rectal rectal JJ cord-022526-j9kg00qf 1394 2 examination examination NN cord-022526-j9kg00qf 1394 3 and and CC cord-022526-j9kg00qf 1394 4 ultrasound ultrasound NN cord-022526-j9kg00qf 1394 5 reveal reveal VB cord-022526-j9kg00qf 1394 6 small small JJ cord-022526-j9kg00qf 1394 7 intestinal intestinal JJ cord-022526-j9kg00qf 1394 8 distention distention NN cord-022526-j9kg00qf 1394 9 with with IN cord-022526-j9kg00qf 1394 10 rare rare JJ cord-022526-j9kg00qf 1394 11 or or CC cord-022526-j9kg00qf 1394 12 absent absent JJ cord-022526-j9kg00qf 1394 13 wall wall NN cord-022526-j9kg00qf 1394 14 movement movement NN cord-022526-j9kg00qf 1394 15 . . . cord-022526-j9kg00qf 1395 1 The the DT cord-022526-j9kg00qf 1395 2 severity severity NN cord-022526-j9kg00qf 1395 3 and and CC cord-022526-j9kg00qf 1395 4 duration duration NN cord-022526-j9kg00qf 1395 5 of of IN cord-022526-j9kg00qf 1395 6 intestinal intestinal JJ cord-022526-j9kg00qf 1395 7 stasis stasis NN cord-022526-j9kg00qf 1395 8 varies vary VBZ cord-022526-j9kg00qf 1395 9 , , , cord-022526-j9kg00qf 1395 10 lasting last VBG cord-022526-j9kg00qf 1395 11 from from IN cord-022526-j9kg00qf 1395 12 minutes minute NNS cord-022526-j9kg00qf 1395 13 to to IN cord-022526-j9kg00qf 1395 14 days day NNS cord-022526-j9kg00qf 1395 15 . . . cord-022526-j9kg00qf 1396 1 A a DT cord-022526-j9kg00qf 1396 2 specific specific JJ cord-022526-j9kg00qf 1396 3 motility motility NN cord-022526-j9kg00qf 1396 4 disorder disorder NN cord-022526-j9kg00qf 1396 5 involving involve VBG cord-022526-j9kg00qf 1396 6 the the DT cord-022526-j9kg00qf 1396 7 cecum cecum NN cord-022526-j9kg00qf 1396 8 or or CC cord-022526-j9kg00qf 1396 9 ileocecocolic ileocecocolic NN cord-022526-j9kg00qf 1396 10 region region NN cord-022526-j9kg00qf 1396 11 occurs occur VBZ cord-022526-j9kg00qf 1396 12 sporadically sporadically RB cord-022526-j9kg00qf 1396 13 in in IN cord-022526-j9kg00qf 1396 14 horses horse NNS cord-022526-j9kg00qf 1396 15 . . . cord-022526-j9kg00qf 1397 1 [ [ -LRB- cord-022526-j9kg00qf 1397 2 5 5 CD cord-022526-j9kg00qf 1397 3 ] ] -RRB- cord-022526-j9kg00qf 1397 4 [ [ -LRB- cord-022526-j9kg00qf 1397 5 6 6 CD cord-022526-j9kg00qf 1397 6 ] ] -RRB- cord-022526-j9kg00qf 1397 7 [ [ -LRB- cord-022526-j9kg00qf 1397 8 7 7 CD cord-022526-j9kg00qf 1397 9 ] ] -RRB- cord-022526-j9kg00qf 1398 1 The the DT cord-022526-j9kg00qf 1398 2 condition condition NN cord-022526-j9kg00qf 1398 3 most most RBS cord-022526-j9kg00qf 1398 4 commonly commonly RB cord-022526-j9kg00qf 1398 5 occurs occur VBZ cord-022526-j9kg00qf 1398 6 after after IN cord-022526-j9kg00qf 1398 7 general general JJ cord-022526-j9kg00qf 1398 8 anesthesia anesthesia NN cord-022526-j9kg00qf 1398 9 and and CC cord-022526-j9kg00qf 1398 10 extraabdominal extraabdominal JJ cord-022526-j9kg00qf 1398 11 surgery surgery NN cord-022526-j9kg00qf 1398 12 , , , cord-022526-j9kg00qf 1398 13 particularly particularly RB cord-022526-j9kg00qf 1398 14 orthopedic orthopedic JJ cord-022526-j9kg00qf 1398 15 and and CC cord-022526-j9kg00qf 1398 16 upper upper JJ cord-022526-j9kg00qf 1398 17 airway airway NN cord-022526-j9kg00qf 1398 18 procedures procedure NNS cord-022526-j9kg00qf 1398 19 , , , cord-022526-j9kg00qf 1398 20 and and CC cord-022526-j9kg00qf 1398 21 therefore therefore RB cord-022526-j9kg00qf 1398 22 often often RB cord-022526-j9kg00qf 1398 23 is be VBZ cord-022526-j9kg00qf 1398 24 categorized categorize VBN cord-022526-j9kg00qf 1398 25 as as IN cord-022526-j9kg00qf 1398 26 a a DT cord-022526-j9kg00qf 1398 27 form form NN cord-022526-j9kg00qf 1398 28 of of IN cord-022526-j9kg00qf 1398 29 POI POI NNP cord-022526-j9kg00qf 1398 30 . . . cord-022526-j9kg00qf 1399 1 Anecdotally anecdotally RB cord-022526-j9kg00qf 1399 2 , , , cord-022526-j9kg00qf 1399 3 horses horse NNS cord-022526-j9kg00qf 1399 4 at at IN cord-022526-j9kg00qf 1399 5 greatest great JJS cord-022526-j9kg00qf 1399 6 risk risk NN cord-022526-j9kg00qf 1399 7 are be VBP cord-022526-j9kg00qf 1399 8 young young JJ cord-022526-j9kg00qf 1399 9 male male JJ cord-022526-j9kg00qf 1399 10 performance performance NN cord-022526-j9kg00qf 1399 11 animals animal NNS cord-022526-j9kg00qf 1399 12 . . . cord-022526-j9kg00qf 1400 1 Other other JJ cord-022526-j9kg00qf 1400 2 cases case NNS cord-022526-j9kg00qf 1400 3 occur occur VBP cord-022526-j9kg00qf 1400 4 spontaneously spontaneously RB cord-022526-j9kg00qf 1400 5 , , , cord-022526-j9kg00qf 1400 6 often often RB cord-022526-j9kg00qf 1400 7 in in IN cord-022526-j9kg00qf 1400 8 animals animal NNS cord-022526-j9kg00qf 1400 9 with with IN cord-022526-j9kg00qf 1400 10 painful painful JJ cord-022526-j9kg00qf 1400 11 primary primary JJ cord-022526-j9kg00qf 1400 12 conditions condition NNS cord-022526-j9kg00qf 1400 13 such such JJ cord-022526-j9kg00qf 1400 14 as as IN cord-022526-j9kg00qf 1400 15 uveitis uveitis NN cord-022526-j9kg00qf 1400 16 or or CC cord-022526-j9kg00qf 1400 17 septic septic JJ cord-022526-j9kg00qf 1400 18 tenosynovitis tenosynovitis NN cord-022526-j9kg00qf 1400 19 . . . cord-022526-j9kg00qf 1401 1 The the DT cord-022526-j9kg00qf 1401 2 syndrome syndrome NN cord-022526-j9kg00qf 1401 3 is be VBZ cord-022526-j9kg00qf 1401 4 frustrating frustrating JJ cord-022526-j9kg00qf 1401 5 in in IN cord-022526-j9kg00qf 1401 6 that that DT cord-022526-j9kg00qf 1401 7 clinical clinical JJ cord-022526-j9kg00qf 1401 8 signs sign NNS cord-022526-j9kg00qf 1401 9 are be VBP cord-022526-j9kg00qf 1401 10 often often RB cord-022526-j9kg00qf 1401 11 subtle subtle JJ cord-022526-j9kg00qf 1401 12 unless unless IN cord-022526-j9kg00qf 1401 13 cecal cecal JJ cord-022526-j9kg00qf 1401 14 perforation perforation NN cord-022526-j9kg00qf 1401 15 has have VBZ cord-022526-j9kg00qf 1401 16 occurred occur VBN cord-022526-j9kg00qf 1401 17 . . . cord-022526-j9kg00qf 1402 1 In in IN cord-022526-j9kg00qf 1402 2 horses horse NNS cord-022526-j9kg00qf 1402 3 with with IN cord-022526-j9kg00qf 1402 4 a a DT cord-022526-j9kg00qf 1402 5 cecal cecal JJ cord-022526-j9kg00qf 1402 6 emptying emptying NN cord-022526-j9kg00qf 1402 7 defect defect NN cord-022526-j9kg00qf 1402 8 after after IN cord-022526-j9kg00qf 1402 9 anesthesia anesthesia NN cord-022526-j9kg00qf 1402 10 , , , cord-022526-j9kg00qf 1402 11 overt overt JJ cord-022526-j9kg00qf 1402 12 signs sign NNS cord-022526-j9kg00qf 1402 13 are be VBP cord-022526-j9kg00qf 1402 14 usually usually RB cord-022526-j9kg00qf 1402 15 apparent apparent JJ cord-022526-j9kg00qf 1402 16 3 3 CD cord-022526-j9kg00qf 1402 17 to to TO cord-022526-j9kg00qf 1402 18 5 5 CD cord-022526-j9kg00qf 1402 19 days day NNS cord-022526-j9kg00qf 1402 20 after after IN cord-022526-j9kg00qf 1402 21 the the DT cord-022526-j9kg00qf 1402 22 procedure procedure NN cord-022526-j9kg00qf 1402 23 . . . cord-022526-j9kg00qf 1403 1 The the DT cord-022526-j9kg00qf 1403 2 earliest early JJS cord-022526-j9kg00qf 1403 3 detectable detectable JJ cord-022526-j9kg00qf 1403 4 signs sign NNS cord-022526-j9kg00qf 1403 5 include include VBP cord-022526-j9kg00qf 1403 6 depression depression NN cord-022526-j9kg00qf 1403 7 and and CC cord-022526-j9kg00qf 1403 8 a a DT cord-022526-j9kg00qf 1403 9 reduction reduction NN cord-022526-j9kg00qf 1403 10 in in IN cord-022526-j9kg00qf 1403 11 feed feed NN cord-022526-j9kg00qf 1403 12 intake intake NN cord-022526-j9kg00qf 1403 13 and and CC cord-022526-j9kg00qf 1403 14 fecal fecal JJ cord-022526-j9kg00qf 1403 15 output output NN cord-022526-j9kg00qf 1403 16 . . . cord-022526-j9kg00qf 1404 1 Ineffective ineffective JJ cord-022526-j9kg00qf 1404 2 emptying emptying NN cord-022526-j9kg00qf 1404 3 results result NNS cord-022526-j9kg00qf 1404 4 in in IN cord-022526-j9kg00qf 1404 5 overfilling overfilling NN cord-022526-j9kg00qf 1404 6 of of IN cord-022526-j9kg00qf 1404 7 the the DT cord-022526-j9kg00qf 1404 8 cecum cecum NN cord-022526-j9kg00qf 1404 9 with with IN cord-022526-j9kg00qf 1404 10 moist moist JJ cord-022526-j9kg00qf 1404 11 contents content NNS cord-022526-j9kg00qf 1404 12 , , , cord-022526-j9kg00qf 1404 13 which which WDT cord-022526-j9kg00qf 1404 14 is be VBZ cord-022526-j9kg00qf 1404 15 manifest manifest JJ cord-022526-j9kg00qf 1404 16 by by IN cord-022526-j9kg00qf 1404 17 signs sign NNS cord-022526-j9kg00qf 1404 18 of of IN cord-022526-j9kg00qf 1404 19 mild mild JJ cord-022526-j9kg00qf 1404 20 to to IN cord-022526-j9kg00qf 1404 21 moderate moderate JJ cord-022526-j9kg00qf 1404 22 colic colic NN cord-022526-j9kg00qf 1404 23 . . . cord-022526-j9kg00qf 1405 1 If if IN cord-022526-j9kg00qf 1405 2 the the DT cord-022526-j9kg00qf 1405 3 condition condition NN cord-022526-j9kg00qf 1405 4 is be VBZ cord-022526-j9kg00qf 1405 5 recognized recognize VBN cord-022526-j9kg00qf 1405 6 late late JJ cord-022526-j9kg00qf 1405 7 or or CC cord-022526-j9kg00qf 1405 8 untreated untreated JJ cord-022526-j9kg00qf 1405 9 , , , cord-022526-j9kg00qf 1405 10 the the DT cord-022526-j9kg00qf 1405 11 cecum cecum NN cord-022526-j9kg00qf 1405 12 may may MD cord-022526-j9kg00qf 1405 13 rupture rupture VB cord-022526-j9kg00qf 1405 14 and and CC cord-022526-j9kg00qf 1405 15 result result VB cord-022526-j9kg00qf 1405 16 in in IN cord-022526-j9kg00qf 1405 17 fatal fatal JJ cord-022526-j9kg00qf 1405 18 peritonitis peritonitis NN cord-022526-j9kg00qf 1405 19 . . . cord-022526-j9kg00qf 1406 1 The the DT cord-022526-j9kg00qf 1406 2 inherent inherent JJ cord-022526-j9kg00qf 1406 3 rhythmicity rhythmicity NN cord-022526-j9kg00qf 1406 4 of of IN cord-022526-j9kg00qf 1406 5 electric electric JJ cord-022526-j9kg00qf 1406 6 activity activity NN cord-022526-j9kg00qf 1406 7 in in IN cord-022526-j9kg00qf 1406 8 the the DT cord-022526-j9kg00qf 1406 9 intestine intestine NN cord-022526-j9kg00qf 1406 10 is be VBZ cord-022526-j9kg00qf 1406 11 controlled control VBN cord-022526-j9kg00qf 1406 12 by by IN cord-022526-j9kg00qf 1406 13 the the DT cord-022526-j9kg00qf 1406 14 interstitial interstitial JJ cord-022526-j9kg00qf 1406 15 cells cell NNS cord-022526-j9kg00qf 1406 16 of of IN cord-022526-j9kg00qf 1406 17 Cajal Cajal NNP cord-022526-j9kg00qf 1406 18 , , , cord-022526-j9kg00qf 1406 19 specialized specialized JJ cord-022526-j9kg00qf 1406 20 cells cell NNS cord-022526-j9kg00qf 1406 21 that that WDT cord-022526-j9kg00qf 1406 22 are be VBP cord-022526-j9kg00qf 1406 23 electrically electrically RB cord-022526-j9kg00qf 1406 24 coupled couple VBN cord-022526-j9kg00qf 1406 25 to to IN cord-022526-j9kg00qf 1406 26 myocytes myocytes NN cord-022526-j9kg00qf 1406 27 via via IN cord-022526-j9kg00qf 1406 28 gap gap NN cord-022526-j9kg00qf 1406 29 junctions junction NNS cord-022526-j9kg00qf 1406 30 . . . cord-022526-j9kg00qf 1407 1 8 8 CD cord-022526-j9kg00qf 1408 1 These these DT cord-022526-j9kg00qf 1408 2 cells cell NNS cord-022526-j9kg00qf 1408 3 are be VBP cord-022526-j9kg00qf 1408 4 responsible responsible JJ cord-022526-j9kg00qf 1408 5 for for IN cord-022526-j9kg00qf 1408 6 generating generate VBG cord-022526-j9kg00qf 1408 7 and and CC cord-022526-j9kg00qf 1408 8 propagating propagate VBG cord-022526-j9kg00qf 1408 9 slow slow JJ cord-022526-j9kg00qf 1408 10 - - HYPH cord-022526-j9kg00qf 1408 11 wave wave NN cord-022526-j9kg00qf 1408 12 activity activity NN cord-022526-j9kg00qf 1408 13 and and CC cord-022526-j9kg00qf 1408 14 may may MD cord-022526-j9kg00qf 1408 15 be be VB cord-022526-j9kg00qf 1408 16 critically critically RB cord-022526-j9kg00qf 1408 17 involved involve VBN cord-022526-j9kg00qf 1408 18 in in IN cord-022526-j9kg00qf 1408 19 a a DT cord-022526-j9kg00qf 1408 20 range range NN cord-022526-j9kg00qf 1408 21 of of IN cord-022526-j9kg00qf 1408 22 motility motility NN cord-022526-j9kg00qf 1408 23 disorders disorder NNS cord-022526-j9kg00qf 1408 24 . . . cord-022526-j9kg00qf 1409 1 The the DT cord-022526-j9kg00qf 1409 2 enteric enteric JJ cord-022526-j9kg00qf 1409 3 nervous nervous JJ cord-022526-j9kg00qf 1409 4 system system NN cord-022526-j9kg00qf 1409 5 primarily primarily RB cord-022526-j9kg00qf 1409 6 controls control VBZ cord-022526-j9kg00qf 1409 7 and and CC cord-022526-j9kg00qf 1409 8 coordinates coordinate VBZ cord-022526-j9kg00qf 1409 9 intestinal intestinal JJ cord-022526-j9kg00qf 1409 10 contraction contraction NN cord-022526-j9kg00qf 1409 11 . . . cord-022526-j9kg00qf 1410 1 A a DT cord-022526-j9kg00qf 1410 2 combination combination NN cord-022526-j9kg00qf 1410 3 of of IN cord-022526-j9kg00qf 1410 4 central central JJ cord-022526-j9kg00qf 1410 5 and and CC cord-022526-j9kg00qf 1410 6 autonomic autonomic JJ cord-022526-j9kg00qf 1410 7 innervation innervation NN cord-022526-j9kg00qf 1410 8 influences influence VBZ cord-022526-j9kg00qf 1410 9 events event NNS cord-022526-j9kg00qf 1410 10 , , , cord-022526-j9kg00qf 1410 11 but but CC cord-022526-j9kg00qf 1410 12 contraction contraction NN cord-022526-j9kg00qf 1410 13 does do VBZ cord-022526-j9kg00qf 1410 14 not not RB cord-022526-j9kg00qf 1410 15 require require VB cord-022526-j9kg00qf 1410 16 external external JJ cord-022526-j9kg00qf 1410 17 neural neural JJ cord-022526-j9kg00qf 1410 18 input input NN cord-022526-j9kg00qf 1410 19 . . . cord-022526-j9kg00qf 1411 1 The the DT cord-022526-j9kg00qf 1411 2 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 1411 3 supply supply NN cord-022526-j9kg00qf 1411 4 to to IN cord-022526-j9kg00qf 1411 5 the the DT cord-022526-j9kg00qf 1411 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1411 7 tract tract NN cord-022526-j9kg00qf 1411 8 is be VBZ cord-022526-j9kg00qf 1411 9 via via IN cord-022526-j9kg00qf 1411 10 the the DT cord-022526-j9kg00qf 1411 11 vagus vagus NN cord-022526-j9kg00qf 1411 12 and and CC cord-022526-j9kg00qf 1411 13 pelvic pelvic JJ cord-022526-j9kg00qf 1411 14 nerves nerve NNS cord-022526-j9kg00qf 1411 15 , , , cord-022526-j9kg00qf 1411 16 and and CC cord-022526-j9kg00qf 1411 17 the the DT cord-022526-j9kg00qf 1411 18 sympathetic sympathetic JJ cord-022526-j9kg00qf 1411 19 supply supply NN cord-022526-j9kg00qf 1411 20 is be VBZ cord-022526-j9kg00qf 1411 21 through through IN cord-022526-j9kg00qf 1411 22 postganglionic postganglionic JJ cord-022526-j9kg00qf 1411 23 fibers fiber NNS cord-022526-j9kg00qf 1411 24 of of IN cord-022526-j9kg00qf 1411 25 the the DT cord-022526-j9kg00qf 1411 26 cranial cranial JJ cord-022526-j9kg00qf 1411 27 and and CC cord-022526-j9kg00qf 1411 28 caudal caudal JJ cord-022526-j9kg00qf 1411 29 mesenteric mesenteric JJ cord-022526-j9kg00qf 1411 30 plexuses plexus NNS cord-022526-j9kg00qf 1411 31 . . . cord-022526-j9kg00qf 1412 1 A a DT cord-022526-j9kg00qf 1412 2 complex complex JJ cord-022526-j9kg00qf 1412 3 network network NN cord-022526-j9kg00qf 1412 4 of of IN cord-022526-j9kg00qf 1412 5 interneurons interneuron NNS cord-022526-j9kg00qf 1412 6 within within IN cord-022526-j9kg00qf 1412 7 each each DT cord-022526-j9kg00qf 1412 8 plexus plexus NN cord-022526-j9kg00qf 1412 9 integrates integrate VBZ cord-022526-j9kg00qf 1412 10 and and CC cord-022526-j9kg00qf 1412 11 amplifies amplify VBZ cord-022526-j9kg00qf 1412 12 neural neural JJ cord-022526-j9kg00qf 1412 13 input input NN cord-022526-j9kg00qf 1412 14 ; ; : cord-022526-j9kg00qf 1412 15 the the DT cord-022526-j9kg00qf 1412 16 intensity intensity NN cord-022526-j9kg00qf 1412 17 and and CC cord-022526-j9kg00qf 1412 18 frequency frequency NN cord-022526-j9kg00qf 1412 19 of of IN cord-022526-j9kg00qf 1412 20 resultant resultant JJ cord-022526-j9kg00qf 1412 21 smooth smooth JJ cord-022526-j9kg00qf 1412 22 muscle muscle NN cord-022526-j9kg00qf 1412 23 contractions contraction NNS cord-022526-j9kg00qf 1412 24 are be VBP cord-022526-j9kg00qf 1412 25 proportional proportional JJ cord-022526-j9kg00qf 1412 26 to to IN cord-022526-j9kg00qf 1412 27 the the DT cord-022526-j9kg00qf 1412 28 amount amount NN cord-022526-j9kg00qf 1412 29 of of IN cord-022526-j9kg00qf 1412 30 sympathetic sympathetic JJ cord-022526-j9kg00qf 1412 31 and and CC cord-022526-j9kg00qf 1412 32 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 1412 33 input input NN cord-022526-j9kg00qf 1412 34 . . . cord-022526-j9kg00qf 1413 1 Additional additional JJ cord-022526-j9kg00qf 1413 2 binding binding NN cord-022526-j9kg00qf 1413 3 sites site NNS cord-022526-j9kg00qf 1413 4 for for IN cord-022526-j9kg00qf 1413 5 a a DT cord-022526-j9kg00qf 1413 6 number number NN cord-022526-j9kg00qf 1413 7 of of IN cord-022526-j9kg00qf 1413 8 other other JJ cord-022526-j9kg00qf 1413 9 endogenous endogenous JJ cord-022526-j9kg00qf 1413 10 chemicals chemical NNS cord-022526-j9kg00qf 1413 11 , , , cord-022526-j9kg00qf 1413 12 including include VBG cord-022526-j9kg00qf 1413 13 dopamine dopamine NN cord-022526-j9kg00qf 1413 14 , , , cord-022526-j9kg00qf 1413 15 motilin motilin NN cord-022526-j9kg00qf 1413 16 , , , cord-022526-j9kg00qf 1413 17 and and CC cord-022526-j9kg00qf 1413 18 serotonin serotonin NN cord-022526-j9kg00qf 1413 19 exist exist VBP cord-022526-j9kg00qf 1413 20 within within IN cord-022526-j9kg00qf 1413 21 the the DT cord-022526-j9kg00qf 1413 22 enteric enteric JJ cord-022526-j9kg00qf 1413 23 nervous nervous JJ cord-022526-j9kg00qf 1413 24 system system NN cord-022526-j9kg00qf 1413 25 and and CC cord-022526-j9kg00qf 1413 26 on on IN cord-022526-j9kg00qf 1413 27 smooth smooth JJ cord-022526-j9kg00qf 1413 28 muscle muscle NN cord-022526-j9kg00qf 1413 29 cells cell NNS cord-022526-j9kg00qf 1413 30 . . . cord-022526-j9kg00qf 1414 1 9 9 CD cord-022526-j9kg00qf 1414 2 Acetylcholine acetylcholine NN cord-022526-j9kg00qf 1414 3 is be VBZ cord-022526-j9kg00qf 1414 4 the the DT cord-022526-j9kg00qf 1414 5 dominant dominant JJ cord-022526-j9kg00qf 1414 6 excitatory excitatory JJ cord-022526-j9kg00qf 1414 7 neurotransmitter neurotransmitter NN cord-022526-j9kg00qf 1414 8 in in IN cord-022526-j9kg00qf 1414 9 the the DT cord-022526-j9kg00qf 1414 10 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1414 11 tract tract NN cord-022526-j9kg00qf 1414 12 and and CC cord-022526-j9kg00qf 1414 13 exerts exert VBZ cord-022526-j9kg00qf 1414 14 its -PRON- PRP$ cord-022526-j9kg00qf 1414 15 action action NN cord-022526-j9kg00qf 1414 16 through through IN cord-022526-j9kg00qf 1414 17 muscurinic muscurinic NNP cord-022526-j9kg00qf 1414 18 type type NN cord-022526-j9kg00qf 1414 19 2 2 CD cord-022526-j9kg00qf 1414 20 receptors receptor NNS cord-022526-j9kg00qf 1414 21 on on IN cord-022526-j9kg00qf 1414 22 smooth smooth JJ cord-022526-j9kg00qf 1414 23 muscle muscle NN cord-022526-j9kg00qf 1414 24 cells cell NNS cord-022526-j9kg00qf 1414 25 . . . cord-022526-j9kg00qf 1415 1 Sympathetic sympathetic JJ cord-022526-j9kg00qf 1415 2 fibers fiber NNS cord-022526-j9kg00qf 1415 3 innervating innervate VBG cord-022526-j9kg00qf 1415 4 the the DT cord-022526-j9kg00qf 1415 5 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1415 6 tract tract NN cord-022526-j9kg00qf 1415 7 are be VBP cord-022526-j9kg00qf 1415 8 adrenergic adrenergic JJ cord-022526-j9kg00qf 1415 9 , , , cord-022526-j9kg00qf 1415 10 postganglionic postganglionic JJ cord-022526-j9kg00qf 1415 11 fibers fiber NNS cord-022526-j9kg00qf 1415 12 with with IN cord-022526-j9kg00qf 1415 13 cell cell NN cord-022526-j9kg00qf 1415 14 bodies body NNS cord-022526-j9kg00qf 1415 15 located locate VBN cord-022526-j9kg00qf 1415 16 in in IN cord-022526-j9kg00qf 1415 17 the the DT cord-022526-j9kg00qf 1415 18 prevertebral prevertebral JJ cord-022526-j9kg00qf 1415 19 ganglia ganglion NNS cord-022526-j9kg00qf 1415 20 . . . cord-022526-j9kg00qf 1416 1 Activation activation NN cord-022526-j9kg00qf 1416 2 of of IN cord-022526-j9kg00qf 1416 3 α α NN cord-022526-j9kg00qf 1416 4 2adrenergic 2adrenergic CD cord-022526-j9kg00qf 1416 5 receptors receptor NNS cord-022526-j9kg00qf 1416 6 on on IN cord-022526-j9kg00qf 1416 7 cholinergic cholinergic JJ cord-022526-j9kg00qf 1416 8 neurons neuron NNS cord-022526-j9kg00qf 1416 9 within within IN cord-022526-j9kg00qf 1416 10 enteric enteric JJ cord-022526-j9kg00qf 1416 11 ganglia ganglion NNS cord-022526-j9kg00qf 1416 12 inhibits inhibit VBZ cord-022526-j9kg00qf 1416 13 the the DT cord-022526-j9kg00qf 1416 14 release release NN cord-022526-j9kg00qf 1416 15 of of IN cord-022526-j9kg00qf 1416 16 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1416 17 and and CC cord-022526-j9kg00qf 1416 18 therefore therefore RB cord-022526-j9kg00qf 1416 19 reduces reduce VBZ cord-022526-j9kg00qf 1416 20 intestinal intestinal JJ cord-022526-j9kg00qf 1416 21 contraction contraction NN cord-022526-j9kg00qf 1416 22 . . . cord-022526-j9kg00qf 1417 1 β β NNP cord-022526-j9kg00qf 1417 2 1 1 CD cord-022526-j9kg00qf 1417 3 - - : cord-022526-j9kg00qf 1417 4 , , , cord-022526-j9kg00qf 1417 5 β β NNP cord-022526-j9kg00qf 1417 6 2 2 CD cord-022526-j9kg00qf 1417 7 - - : cord-022526-j9kg00qf 1417 8 , , , cord-022526-j9kg00qf 1417 9 and and CC cord-022526-j9kg00qf 1417 10 β β NN cord-022526-j9kg00qf 1417 11 - - HYPH cord-022526-j9kg00qf 1417 12 atypical atypical JJ cord-022526-j9kg00qf 1417 13 receptors receptor NNS cord-022526-j9kg00qf 1417 14 are be VBP cord-022526-j9kg00qf 1417 15 directly directly RB cord-022526-j9kg00qf 1417 16 inhibitory inhibitory JJ cord-022526-j9kg00qf 1417 17 to to IN cord-022526-j9kg00qf 1417 18 the the DT cord-022526-j9kg00qf 1417 19 intestinal intestinal JJ cord-022526-j9kg00qf 1417 20 smooth smooth JJ cord-022526-j9kg00qf 1417 21 muscle muscle NN cord-022526-j9kg00qf 1417 22 . . . cord-022526-j9kg00qf 1418 1 10 10 CD cord-022526-j9kg00qf 1418 2 Inhibitory inhibitory JJ cord-022526-j9kg00qf 1418 3 nonadrenergic nonadrenergic JJ cord-022526-j9kg00qf 1418 4 , , , cord-022526-j9kg00qf 1418 5 noncholinergic noncholinergic JJ cord-022526-j9kg00qf 1418 6 neurotransmitters neurotransmitter NNS cord-022526-j9kg00qf 1418 7 include include VBP cord-022526-j9kg00qf 1418 8 adenosine adenosine NN cord-022526-j9kg00qf 1418 9 triphosphate triphosphate NN cord-022526-j9kg00qf 1418 10 , , , cord-022526-j9kg00qf 1418 11 vasoactive vasoactive JJ cord-022526-j9kg00qf 1418 12 intestinal intestinal JJ cord-022526-j9kg00qf 1418 13 peptide peptide NN cord-022526-j9kg00qf 1418 14 , , , cord-022526-j9kg00qf 1418 15 and and CC cord-022526-j9kg00qf 1418 16 nitric nitric JJ cord-022526-j9kg00qf 1418 17 oxide oxide NN cord-022526-j9kg00qf 1418 18 . . . cord-022526-j9kg00qf 1419 1 11 11 CD cord-022526-j9kg00qf 1419 2 , , , cord-022526-j9kg00qf 1419 3 12 12 CD cord-022526-j9kg00qf 1419 4 These these DT cord-022526-j9kg00qf 1419 5 neurotransmitters neurotransmitter NNS cord-022526-j9kg00qf 1419 6 are be VBP cord-022526-j9kg00qf 1419 7 critical critical JJ cord-022526-j9kg00qf 1419 8 for for IN cord-022526-j9kg00qf 1419 9 mediating mediate VBG cord-022526-j9kg00qf 1419 10 descending descend VBG cord-022526-j9kg00qf 1419 11 inhibition inhibition NN cord-022526-j9kg00qf 1419 12 during during IN cord-022526-j9kg00qf 1419 13 peristalsis peristalsis NN cord-022526-j9kg00qf 1419 14 and and CC cord-022526-j9kg00qf 1419 15 receptive receptive JJ cord-022526-j9kg00qf 1419 16 relaxation relaxation NN cord-022526-j9kg00qf 1419 17 . . . cord-022526-j9kg00qf 1420 1 Substance substance NN cord-022526-j9kg00qf 1420 2 P p NN cord-022526-j9kg00qf 1420 3 is be VBZ cord-022526-j9kg00qf 1420 4 a a DT cord-022526-j9kg00qf 1420 5 nonadrenergic nonadrenergic JJ cord-022526-j9kg00qf 1420 6 , , , cord-022526-j9kg00qf 1420 7 noncholinergic noncholinergic JJ cord-022526-j9kg00qf 1420 8 neurotransmitter neurotransmitter NN cord-022526-j9kg00qf 1420 9 that that WDT cord-022526-j9kg00qf 1420 10 may may MD cord-022526-j9kg00qf 1420 11 be be VB cord-022526-j9kg00qf 1420 12 involved involve VBN cord-022526-j9kg00qf 1420 13 in in IN cord-022526-j9kg00qf 1420 14 contraction contraction NN cord-022526-j9kg00qf 1420 15 of of IN cord-022526-j9kg00qf 1420 16 the the DT cord-022526-j9kg00qf 1420 17 large large JJ cord-022526-j9kg00qf 1420 18 colon colon NN cord-022526-j9kg00qf 1420 19 . . . cord-022526-j9kg00qf 1421 1 13 13 CD cord-022526-j9kg00qf 1421 2 , , , cord-022526-j9kg00qf 1421 3 14 14 CD cord-022526-j9kg00qf 1422 1 The the DT cord-022526-j9kg00qf 1422 2 rate rate NN cord-022526-j9kg00qf 1422 3 and and CC cord-022526-j9kg00qf 1422 4 force force NN cord-022526-j9kg00qf 1422 5 of of IN cord-022526-j9kg00qf 1422 6 intestinal intestinal JJ cord-022526-j9kg00qf 1422 7 contractions contraction NNS cord-022526-j9kg00qf 1422 8 along along IN cord-022526-j9kg00qf 1422 9 the the DT cord-022526-j9kg00qf 1422 10 small small JJ cord-022526-j9kg00qf 1422 11 intestine intestine NN cord-022526-j9kg00qf 1422 12 and and CC cord-022526-j9kg00qf 1422 13 large large JJ cord-022526-j9kg00qf 1422 14 colon colon NN cord-022526-j9kg00qf 1422 15 of of IN cord-022526-j9kg00qf 1422 16 the the DT cord-022526-j9kg00qf 1422 17 horse horse NN cord-022526-j9kg00qf 1422 18 are be VBP cord-022526-j9kg00qf 1422 19 important important JJ cord-022526-j9kg00qf 1422 20 determinants determinant NNS cord-022526-j9kg00qf 1422 21 of of IN cord-022526-j9kg00qf 1422 22 intestinal intestinal JJ cord-022526-j9kg00qf 1422 23 motility motility NN cord-022526-j9kg00qf 1422 24 ; ; : cord-022526-j9kg00qf 1422 25 of of IN cord-022526-j9kg00qf 1422 26 even even RB cord-022526-j9kg00qf 1422 27 greater great JJR cord-022526-j9kg00qf 1422 28 importance importance NN cord-022526-j9kg00qf 1422 29 to to IN cord-022526-j9kg00qf 1422 30 the the DT cord-022526-j9kg00qf 1422 31 net net JJ cord-022526-j9kg00qf 1422 32 propulsion propulsion NN cord-022526-j9kg00qf 1422 33 of of IN cord-022526-j9kg00qf 1422 34 digesta digesta NNS cord-022526-j9kg00qf 1422 35 are be VBP cord-022526-j9kg00qf 1422 36 the the DT cord-022526-j9kg00qf 1422 37 cyclical cyclical JJ cord-022526-j9kg00qf 1422 38 patterns pattern NNS cord-022526-j9kg00qf 1422 39 of of IN cord-022526-j9kg00qf 1422 40 contractile contractile JJ cord-022526-j9kg00qf 1422 41 activity activity NN cord-022526-j9kg00qf 1422 42 . . . cord-022526-j9kg00qf 1423 1 These these DT cord-022526-j9kg00qf 1423 2 patterns pattern NNS cord-022526-j9kg00qf 1423 3 are be VBP cord-022526-j9kg00qf 1423 4 known know VBN cord-022526-j9kg00qf 1423 5 as as IN cord-022526-j9kg00qf 1423 6 the the DT cord-022526-j9kg00qf 1423 7 small small JJ cord-022526-j9kg00qf 1423 8 intestinal intestinal JJ cord-022526-j9kg00qf 1423 9 and and CC cord-022526-j9kg00qf 1423 10 colonic colonic JJ cord-022526-j9kg00qf 1423 11 migrating migrate VBG cord-022526-j9kg00qf 1423 12 motility motility NN cord-022526-j9kg00qf 1423 13 ( ( -LRB- cord-022526-j9kg00qf 1423 14 or or CC cord-022526-j9kg00qf 1423 15 myoelectric myoelectric JJ cord-022526-j9kg00qf 1423 16 ) ) -RRB- cord-022526-j9kg00qf 1423 17 complexes complex NNS cord-022526-j9kg00qf 1423 18 ( ( -LRB- cord-022526-j9kg00qf 1423 19 MMCs MMCs NNP cord-022526-j9kg00qf 1423 20 ) ) -RRB- cord-022526-j9kg00qf 1423 21 . . . cord-022526-j9kg00qf 1424 1 15 15 CD cord-022526-j9kg00qf 1424 2 , , , cord-022526-j9kg00qf 1424 3 16 16 CD cord-022526-j9kg00qf 1425 1 The the DT cord-022526-j9kg00qf 1425 2 colonic colonic JJ cord-022526-j9kg00qf 1425 3 complex complex NN cord-022526-j9kg00qf 1425 4 usually usually RB cord-022526-j9kg00qf 1425 5 originates originate VBZ cord-022526-j9kg00qf 1425 6 in in IN cord-022526-j9kg00qf 1425 7 the the DT cord-022526-j9kg00qf 1425 8 right right JJ cord-022526-j9kg00qf 1425 9 ventral ventral JJ cord-022526-j9kg00qf 1425 10 colon colon NN cord-022526-j9kg00qf 1425 11 and and CC cord-022526-j9kg00qf 1425 12 variably variably RB cord-022526-j9kg00qf 1425 13 traverses traverse VBZ cord-022526-j9kg00qf 1425 14 the the DT cord-022526-j9kg00qf 1425 15 ascending ascend VBG cord-022526-j9kg00qf 1425 16 and and CC cord-022526-j9kg00qf 1425 17 descending descend VBG cord-022526-j9kg00qf 1425 18 colons colon NNS cord-022526-j9kg00qf 1425 19 . . . cord-022526-j9kg00qf 1426 1 Many many JJ cord-022526-j9kg00qf 1426 2 of of IN cord-022526-j9kg00qf 1426 3 these these DT cord-022526-j9kg00qf 1426 4 complexes complex NNS cord-022526-j9kg00qf 1426 5 are be VBP cord-022526-j9kg00qf 1426 6 related relate VBN cord-022526-j9kg00qf 1426 7 temporally temporally RB cord-022526-j9kg00qf 1426 8 to to IN cord-022526-j9kg00qf 1426 9 a a DT cord-022526-j9kg00qf 1426 10 specialized specialized JJ cord-022526-j9kg00qf 1426 11 motility motility NN cord-022526-j9kg00qf 1426 12 event event NN cord-022526-j9kg00qf 1426 13 of of IN cord-022526-j9kg00qf 1426 14 the the DT cord-022526-j9kg00qf 1426 15 ileum ileum NN cord-022526-j9kg00qf 1426 16 , , , cord-022526-j9kg00qf 1426 17 the the DT cord-022526-j9kg00qf 1426 18 migrating migrate VBG cord-022526-j9kg00qf 1426 19 action action NN cord-022526-j9kg00qf 1426 20 potential potential JJ cord-022526-j9kg00qf 1426 21 complex complex NN cord-022526-j9kg00qf 1426 22 . . . cord-022526-j9kg00qf 1427 1 Local local JJ cord-022526-j9kg00qf 1427 2 inflammation inflammation NN cord-022526-j9kg00qf 1427 3 within within IN cord-022526-j9kg00qf 1427 4 the the DT cord-022526-j9kg00qf 1427 5 intestinal intestinal JJ cord-022526-j9kg00qf 1427 6 muscularis muscularis NN cord-022526-j9kg00qf 1427 7 and and CC cord-022526-j9kg00qf 1427 8 inhibitory inhibitory JJ cord-022526-j9kg00qf 1427 9 neural neural JJ cord-022526-j9kg00qf 1427 10 events event NNS cord-022526-j9kg00qf 1427 11 are be VBP cord-022526-j9kg00qf 1427 12 important important JJ cord-022526-j9kg00qf 1427 13 initiators initiator NNS cord-022526-j9kg00qf 1427 14 of of IN cord-022526-j9kg00qf 1427 15 intestinal intestinal JJ cord-022526-j9kg00qf 1427 16 ileus ileus NN cord-022526-j9kg00qf 1427 17 . . . cord-022526-j9kg00qf 1428 1 17 17 CD cord-022526-j9kg00qf 1428 2 , , , cord-022526-j9kg00qf 1428 3 18 18 CD cord-022526-j9kg00qf 1428 4 Intestinal intestinal JJ cord-022526-j9kg00qf 1428 5 inflammation inflammation NN cord-022526-j9kg00qf 1428 6 not not RB cord-022526-j9kg00qf 1428 7 only only RB cord-022526-j9kg00qf 1428 8 is be VBZ cord-022526-j9kg00qf 1428 9 important important JJ cord-022526-j9kg00qf 1428 10 in in IN cord-022526-j9kg00qf 1428 11 primary primary JJ cord-022526-j9kg00qf 1428 12 intestinal intestinal JJ cord-022526-j9kg00qf 1428 13 diseases disease NNS cord-022526-j9kg00qf 1428 14 in in IN cord-022526-j9kg00qf 1428 15 horses horse NNS cord-022526-j9kg00qf 1428 16 , , , cord-022526-j9kg00qf 1428 17 such such JJ cord-022526-j9kg00qf 1428 18 as as IN cord-022526-j9kg00qf 1428 19 duodenitis duodenitis NN cord-022526-j9kg00qf 1428 20 - - HYPH cord-022526-j9kg00qf 1428 21 proximal proximal JJ cord-022526-j9kg00qf 1428 22 jejunitis jejunitis NN cord-022526-j9kg00qf 1428 23 and and CC cord-022526-j9kg00qf 1428 24 colitis colitis NN cord-022526-j9kg00qf 1428 25 but but CC cord-022526-j9kg00qf 1428 26 also also RB cord-022526-j9kg00qf 1428 27 is be VBZ cord-022526-j9kg00qf 1428 28 induced induce VBN cord-022526-j9kg00qf 1428 29 after after IN cord-022526-j9kg00qf 1428 30 simple simple JJ cord-022526-j9kg00qf 1428 31 intestinal intestinal JJ cord-022526-j9kg00qf 1428 32 handling handling NN cord-022526-j9kg00qf 1428 33 during during IN cord-022526-j9kg00qf 1428 34 laparotomy laparotomy NN cord-022526-j9kg00qf 1428 35 . . . cord-022526-j9kg00qf 1429 1 Experimental experimental JJ cord-022526-j9kg00qf 1429 2 data datum NNS cord-022526-j9kg00qf 1429 3 from from IN cord-022526-j9kg00qf 1429 4 other other JJ cord-022526-j9kg00qf 1429 5 species specie NNS cord-022526-j9kg00qf 1429 6 suggests suggest VBZ cord-022526-j9kg00qf 1429 7 that that IN cord-022526-j9kg00qf 1429 8 handling handling NN cord-022526-j9kg00qf 1429 9 of of IN cord-022526-j9kg00qf 1429 10 the the DT cord-022526-j9kg00qf 1429 11 small small JJ cord-022526-j9kg00qf 1429 12 or or CC cord-022526-j9kg00qf 1429 13 large large JJ cord-022526-j9kg00qf 1429 14 intestine intestine NN cord-022526-j9kg00qf 1429 15 at at IN cord-022526-j9kg00qf 1429 16 the the DT cord-022526-j9kg00qf 1429 17 time time NN cord-022526-j9kg00qf 1429 18 of of IN cord-022526-j9kg00qf 1429 19 surgery surgery NN cord-022526-j9kg00qf 1429 20 activates activate VBZ cord-022526-j9kg00qf 1429 21 resident resident JJ cord-022526-j9kg00qf 1429 22 macrophages macrophage NNS cord-022526-j9kg00qf 1429 23 with with IN cord-022526-j9kg00qf 1429 24 resultant resultant JJ cord-022526-j9kg00qf 1429 25 increased increase VBN cord-022526-j9kg00qf 1429 26 expression expression NN cord-022526-j9kg00qf 1429 27 of of IN cord-022526-j9kg00qf 1429 28 P p NN cord-022526-j9kg00qf 1429 29 - - HYPH cord-022526-j9kg00qf 1429 30 selectin selectin NNS cord-022526-j9kg00qf 1429 31 and and CC cord-022526-j9kg00qf 1429 32 intercellular intercellular JJ cord-022526-j9kg00qf 1429 33 adhesion adhesion NN cord-022526-j9kg00qf 1429 34 molecule molecule NN cord-022526-j9kg00qf 1429 35 1 1 CD cord-022526-j9kg00qf 1429 36 on on IN cord-022526-j9kg00qf 1429 37 endothelial endothelial JJ cord-022526-j9kg00qf 1429 38 cells cell NNS cord-022526-j9kg00qf 1429 39 within within IN cord-022526-j9kg00qf 1429 40 the the DT cord-022526-j9kg00qf 1429 41 vasculature vasculature NN cord-022526-j9kg00qf 1429 42 of of IN cord-022526-j9kg00qf 1429 43 the the DT cord-022526-j9kg00qf 1429 44 muscularis muscularis NNP cord-022526-j9kg00qf 1429 45 . . . cord-022526-j9kg00qf 1430 1 The the DT cord-022526-j9kg00qf 1430 2 upregulation upregulation NN cord-022526-j9kg00qf 1430 3 of of IN cord-022526-j9kg00qf 1430 4 associated associated JJ cord-022526-j9kg00qf 1430 5 ligands ligand NNS cord-022526-j9kg00qf 1430 6 on on IN cord-022526-j9kg00qf 1430 7 leukocytes leukocyte NNS cord-022526-j9kg00qf 1430 8 leads lead VBZ cord-022526-j9kg00qf 1430 9 to to TO cord-022526-j9kg00qf 1430 10 sequential sequential JJ cord-022526-j9kg00qf 1430 11 " " `` cord-022526-j9kg00qf 1430 12 sticking sticking JJ cord-022526-j9kg00qf 1430 13 and and CC cord-022526-j9kg00qf 1430 14 rolling rolling NN cord-022526-j9kg00qf 1430 15 , , , cord-022526-j9kg00qf 1430 16 " " '' cord-022526-j9kg00qf 1430 17 followed follow VBN cord-022526-j9kg00qf 1430 18 by by IN cord-022526-j9kg00qf 1430 19 neutrophil neutrophil NN cord-022526-j9kg00qf 1430 20 migration migration NN cord-022526-j9kg00qf 1430 21 into into IN cord-022526-j9kg00qf 1430 22 the the DT cord-022526-j9kg00qf 1430 23 interstitium interstitium NN cord-022526-j9kg00qf 1430 24 . . . cord-022526-j9kg00qf 1431 1 The the DT cord-022526-j9kg00qf 1431 2 subsequent subsequent JJ cord-022526-j9kg00qf 1431 3 release release NN cord-022526-j9kg00qf 1431 4 of of IN cord-022526-j9kg00qf 1431 5 neutrophil neutrophil NN cord-022526-j9kg00qf 1431 6 products product NNS cord-022526-j9kg00qf 1431 7 interferes interfere VBZ cord-022526-j9kg00qf 1431 8 with with IN cord-022526-j9kg00qf 1431 9 cell cell NN cord-022526-j9kg00qf 1431 10 signaling signaling NN cord-022526-j9kg00qf 1431 11 and and CC cord-022526-j9kg00qf 1431 12 results result NNS cord-022526-j9kg00qf 1431 13 in in IN cord-022526-j9kg00qf 1431 14 reduced reduce VBN cord-022526-j9kg00qf 1431 15 intensity intensity NN cord-022526-j9kg00qf 1431 16 of of IN cord-022526-j9kg00qf 1431 17 smooth smooth JJ cord-022526-j9kg00qf 1431 18 muscle muscle NN cord-022526-j9kg00qf 1431 19 contraction contraction NN cord-022526-j9kg00qf 1431 20 . . . cord-022526-j9kg00qf 1432 1 Furthermore furthermore RB cord-022526-j9kg00qf 1432 2 , , , cord-022526-j9kg00qf 1432 3 the the DT cord-022526-j9kg00qf 1432 4 inflamed inflamed JJ cord-022526-j9kg00qf 1432 5 intestine intestine NN cord-022526-j9kg00qf 1432 6 fails fail VBZ cord-022526-j9kg00qf 1432 7 to to TO cord-022526-j9kg00qf 1432 8 contract contract VB cord-022526-j9kg00qf 1432 9 normally normally RB cord-022526-j9kg00qf 1432 10 in in IN cord-022526-j9kg00qf 1432 11 response response NN cord-022526-j9kg00qf 1432 12 to to IN cord-022526-j9kg00qf 1432 13 putative putative JJ cord-022526-j9kg00qf 1432 14 prokinetic prokinetic JJ cord-022526-j9kg00qf 1432 15 agents agent NNS cord-022526-j9kg00qf 1432 16 . . . cord-022526-j9kg00qf 1433 1 Another another DT cord-022526-j9kg00qf 1433 2 key key JJ cord-022526-j9kg00qf 1433 3 factor factor NN cord-022526-j9kg00qf 1433 4 in in IN cord-022526-j9kg00qf 1433 5 the the DT cord-022526-j9kg00qf 1433 6 development development NN cord-022526-j9kg00qf 1433 7 of of IN cord-022526-j9kg00qf 1433 8 intestinal intestinal JJ cord-022526-j9kg00qf 1433 9 stasis stasis NN cord-022526-j9kg00qf 1433 10 after after IN cord-022526-j9kg00qf 1433 11 inflammation inflammation NN cord-022526-j9kg00qf 1433 12 is be VBZ cord-022526-j9kg00qf 1433 13 the the DT cord-022526-j9kg00qf 1433 14 local local JJ cord-022526-j9kg00qf 1433 15 overproduction overproduction NN cord-022526-j9kg00qf 1433 16 of of IN cord-022526-j9kg00qf 1433 17 nitric nitric NN cord-022526-j9kg00qf 1433 18 oxide oxide NN cord-022526-j9kg00qf 1433 19 caused cause VBN cord-022526-j9kg00qf 1433 20 by by IN cord-022526-j9kg00qf 1433 21 the the DT cord-022526-j9kg00qf 1433 22 upregulation upregulation NN cord-022526-j9kg00qf 1433 23 of of IN cord-022526-j9kg00qf 1433 24 inducible inducible JJ cord-022526-j9kg00qf 1433 25 nitric nitric NN cord-022526-j9kg00qf 1433 26 oxide oxide NN cord-022526-j9kg00qf 1433 27 synthase synthase NN cord-022526-j9kg00qf 1433 28 ( ( -LRB- cord-022526-j9kg00qf 1433 29 iNOS inos NN cord-022526-j9kg00qf 1433 30 ) ) -RRB- cord-022526-j9kg00qf 1433 31 by by IN cord-022526-j9kg00qf 1433 32 resident resident JJ cord-022526-j9kg00qf 1433 33 macrophages macrophage NNS cord-022526-j9kg00qf 1433 34 . . . cord-022526-j9kg00qf 1434 1 Nitric nitric NN cord-022526-j9kg00qf 1434 2 oxide oxide NN cord-022526-j9kg00qf 1434 3 is be VBZ cord-022526-j9kg00qf 1434 4 a a DT cord-022526-j9kg00qf 1434 5 key key JJ cord-022526-j9kg00qf 1434 6 inhibitory inhibitory JJ cord-022526-j9kg00qf 1434 7 neurotransmitter neurotransmitter NN cord-022526-j9kg00qf 1434 8 of of IN cord-022526-j9kg00qf 1434 9 the the DT cord-022526-j9kg00qf 1434 10 nonadrenergic nonadrenergic JJ cord-022526-j9kg00qf 1434 11 , , , cord-022526-j9kg00qf 1434 12 noncholinergic noncholinergic JJ cord-022526-j9kg00qf 1434 13 system system NN cord-022526-j9kg00qf 1434 14 . . . cord-022526-j9kg00qf 1435 1 12 12 CD cord-022526-j9kg00qf 1435 2 Nitric nitric NN cord-022526-j9kg00qf 1435 3 oxide oxide NN cord-022526-j9kg00qf 1435 4 synthase synthase NN cord-022526-j9kg00qf 1435 5 inhibition inhibition NN cord-022526-j9kg00qf 1435 6 has have VBZ cord-022526-j9kg00qf 1435 7 been be VBN cord-022526-j9kg00qf 1435 8 a a DT cord-022526-j9kg00qf 1435 9 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 1435 10 target target NN cord-022526-j9kg00qf 1435 11 in in IN cord-022526-j9kg00qf 1435 12 the the DT cord-022526-j9kg00qf 1435 13 treatment treatment NN cord-022526-j9kg00qf 1435 14 of of IN cord-022526-j9kg00qf 1435 15 experimental experimental JJ cord-022526-j9kg00qf 1435 16 ileus ileus NN cord-022526-j9kg00qf 1435 17 . . . cord-022526-j9kg00qf 1436 1 The the DT cord-022526-j9kg00qf 1436 2 inhibitory inhibitory JJ cord-022526-j9kg00qf 1436 3 effects effect NNS cord-022526-j9kg00qf 1436 4 of of IN cord-022526-j9kg00qf 1436 5 α α NN cord-022526-j9kg00qf 1436 6 2 2 CD cord-022526-j9kg00qf 1436 7 -agonists -agonist NNS cord-022526-j9kg00qf 1436 8 such such JJ cord-022526-j9kg00qf 1436 9 as as IN cord-022526-j9kg00qf 1436 10 xylazine xylazine NN cord-022526-j9kg00qf 1436 11 and and CC cord-022526-j9kg00qf 1436 12 detomidine detomidine NN cord-022526-j9kg00qf 1436 13 on on IN cord-022526-j9kg00qf 1436 14 cecal cecal JJ cord-022526-j9kg00qf 1436 15 and and CC cord-022526-j9kg00qf 1436 16 large large JJ cord-022526-j9kg00qf 1436 17 colon colon NN cord-022526-j9kg00qf 1436 18 motility motility NN cord-022526-j9kg00qf 1436 19 are be VBP cord-022526-j9kg00qf 1436 20 well well RB cord-022526-j9kg00qf 1436 21 described describe VBN cord-022526-j9kg00qf 1436 22 . . . cord-022526-j9kg00qf 1437 1 [ [ -LRB- cord-022526-j9kg00qf 1437 2 19 19 CD cord-022526-j9kg00qf 1437 3 ] ] -RRB- cord-022526-j9kg00qf 1437 4 [ [ -LRB- cord-022526-j9kg00qf 1437 5 20 20 CD cord-022526-j9kg00qf 1437 6 ] ] -RRB- cord-022526-j9kg00qf 1437 7 [ [ -LRB- cord-022526-j9kg00qf 1437 8 21 21 CD cord-022526-j9kg00qf 1437 9 ] ] -RRB- cord-022526-j9kg00qf 1438 1 [ [ -LRB- cord-022526-j9kg00qf 1438 2 22 22 CD cord-022526-j9kg00qf 1438 3 ] ] -RRB- cord-022526-j9kg00qf 1438 4 [ [ -LRB- cord-022526-j9kg00qf 1438 5 23 23 CD cord-022526-j9kg00qf 1438 6 ] ] -RRB- cord-022526-j9kg00qf 1438 7 [ [ -LRB- cord-022526-j9kg00qf 1438 8 24 24 CD cord-022526-j9kg00qf 1438 9 ] ] -RRB- cord-022526-j9kg00qf 1439 1 Intravenously intravenously RB cord-022526-j9kg00qf 1439 2 administered administer VBN cord-022526-j9kg00qf 1439 3 xylazine xylazine NN cord-022526-j9kg00qf 1439 4 inhibits inhibit VBZ cord-022526-j9kg00qf 1439 5 cecal cecal JJ cord-022526-j9kg00qf 1439 6 and and CC cord-022526-j9kg00qf 1439 7 large large JJ cord-022526-j9kg00qf 1439 8 colon colon NN cord-022526-j9kg00qf 1439 9 motility motility NN cord-022526-j9kg00qf 1439 10 for for IN cord-022526-j9kg00qf 1439 11 20 20 CD cord-022526-j9kg00qf 1439 12 to to TO cord-022526-j9kg00qf 1439 13 30 30 CD cord-022526-j9kg00qf 1439 14 minutes minute NNS cord-022526-j9kg00qf 1439 15 without without IN cord-022526-j9kg00qf 1439 16 seriously seriously RB cord-022526-j9kg00qf 1439 17 disrupting disrupt VBG cord-022526-j9kg00qf 1439 18 small small JJ cord-022526-j9kg00qf 1439 19 intestinal intestinal JJ cord-022526-j9kg00qf 1439 20 myoelectric myoelectric JJ cord-022526-j9kg00qf 1439 21 activity activity NN cord-022526-j9kg00qf 1439 22 , , , cord-022526-j9kg00qf 1439 23 and and CC cord-022526-j9kg00qf 1439 24 detomidine detomidine NN cord-022526-j9kg00qf 1439 25 can can MD cord-022526-j9kg00qf 1439 26 reduce reduce VB cord-022526-j9kg00qf 1439 27 large large JJ cord-022526-j9kg00qf 1439 28 intestinal intestinal JJ cord-022526-j9kg00qf 1439 29 myoelectric myoelectric JJ cord-022526-j9kg00qf 1439 30 activity activity NN cord-022526-j9kg00qf 1439 31 for for IN cord-022526-j9kg00qf 1439 32 up up IN cord-022526-j9kg00qf 1439 33 to to TO cord-022526-j9kg00qf 1439 34 3 3 CD cord-022526-j9kg00qf 1439 35 hours hour NNS cord-022526-j9kg00qf 1439 36 . . . cord-022526-j9kg00qf 1440 1 The the DT cord-022526-j9kg00qf 1440 2 α α NN cord-022526-j9kg00qf 1440 3 2 2 CD cord-022526-j9kg00qf 1440 4 -antagonist -antagonist NN cord-022526-j9kg00qf 1440 5 yohimbine yohimbine NN cord-022526-j9kg00qf 1440 6 has have VBZ cord-022526-j9kg00qf 1440 7 a a DT cord-022526-j9kg00qf 1440 8 weak weak JJ cord-022526-j9kg00qf 1440 9 but but CC cord-022526-j9kg00qf 1440 10 positive positive JJ cord-022526-j9kg00qf 1440 11 effect effect NN cord-022526-j9kg00qf 1440 12 on on IN cord-022526-j9kg00qf 1440 13 cecal cecal JJ cord-022526-j9kg00qf 1440 14 emptying emptying NN cord-022526-j9kg00qf 1440 15 in in IN cord-022526-j9kg00qf 1440 16 normal normal JJ cord-022526-j9kg00qf 1440 17 ponies pony NNS cord-022526-j9kg00qf 1440 18 , , , cord-022526-j9kg00qf 1440 19 suggesting suggest VBG cord-022526-j9kg00qf 1440 20 that that IN cord-022526-j9kg00qf 1440 21 normal normal JJ cord-022526-j9kg00qf 1440 22 motility motility NN cord-022526-j9kg00qf 1440 23 is be VBZ cord-022526-j9kg00qf 1440 24 under under IN cord-022526-j9kg00qf 1440 25 constant constant JJ cord-022526-j9kg00qf 1440 26 α α NN cord-022526-j9kg00qf 1440 27 2 2 CD cord-022526-j9kg00qf 1440 28 -adrenergic -adrenergic JJ cord-022526-j9kg00qf 1440 29 tone tone NN cord-022526-j9kg00qf 1440 30 . . . cord-022526-j9kg00qf 1441 1 24 24 CD cord-022526-j9kg00qf 1441 2 Atropine Atropine NNP cord-022526-j9kg00qf 1441 3 is be VBZ cord-022526-j9kg00qf 1441 4 a a DT cord-022526-j9kg00qf 1441 5 postganglionic postganglionic JJ cord-022526-j9kg00qf 1441 6 blocking blocking NN cord-022526-j9kg00qf 1441 7 agent agent NN cord-022526-j9kg00qf 1441 8 that that WDT cord-022526-j9kg00qf 1441 9 binds bind VBZ cord-022526-j9kg00qf 1441 10 to to IN cord-022526-j9kg00qf 1441 11 muscarinic muscarinic JJ cord-022526-j9kg00qf 1441 12 receptors receptor NNS cord-022526-j9kg00qf 1441 13 . . . cord-022526-j9kg00qf 1442 1 When when WRB cord-022526-j9kg00qf 1442 2 administered administer VBN cord-022526-j9kg00qf 1442 3 at at IN cord-022526-j9kg00qf 1442 4 0.04 0.04 CD cord-022526-j9kg00qf 1442 5 mg mg NNP cord-022526-j9kg00qf 1442 6 / / SYM cord-022526-j9kg00qf 1442 7 kg kg NN cord-022526-j9kg00qf 1442 8 , , , cord-022526-j9kg00qf 1442 9 atropine atropine NN cord-022526-j9kg00qf 1442 10 inhibits inhibit VBZ cord-022526-j9kg00qf 1442 11 individual individual JJ cord-022526-j9kg00qf 1442 12 small small JJ cord-022526-j9kg00qf 1442 13 intestinal intestinal JJ cord-022526-j9kg00qf 1442 14 , , , cord-022526-j9kg00qf 1442 15 cecal cecal JJ cord-022526-j9kg00qf 1442 16 , , , cord-022526-j9kg00qf 1442 17 and and CC cord-022526-j9kg00qf 1442 18 colonic colonic JJ cord-022526-j9kg00qf 1442 19 contractions contraction NNS cord-022526-j9kg00qf 1442 20 for for IN cord-022526-j9kg00qf 1442 21 about about RB cord-022526-j9kg00qf 1442 22 120 120 CD cord-022526-j9kg00qf 1442 23 minutes minute NNS cord-022526-j9kg00qf 1442 24 but but CC cord-022526-j9kg00qf 1442 25 supresses supresse VBZ cord-022526-j9kg00qf 1442 26 small small JJ cord-022526-j9kg00qf 1442 27 intestinal intestinal JJ cord-022526-j9kg00qf 1442 28 and and CC cord-022526-j9kg00qf 1442 29 colonic colonic JJ cord-022526-j9kg00qf 1442 30 migrating migrate VBG cord-022526-j9kg00qf 1442 31 complexes complex NNS cord-022526-j9kg00qf 1442 32 for for IN cord-022526-j9kg00qf 1442 33 up up IN cord-022526-j9kg00qf 1442 34 to to TO cord-022526-j9kg00qf 1442 35 8 8 CD cord-022526-j9kg00qf 1442 36 hours hour NNS cord-022526-j9kg00qf 1442 37 . . . cord-022526-j9kg00qf 1443 1 25 25 CD cord-022526-j9kg00qf 1443 2 _SP cord-022526-j9kg00qf 1444 1 Neural neural JJ cord-022526-j9kg00qf 1444 2 reflexes reflex NNS cord-022526-j9kg00qf 1444 3 also also RB cord-022526-j9kg00qf 1444 4 may may MD cord-022526-j9kg00qf 1444 5 mediate mediate VB cord-022526-j9kg00qf 1444 6 inhibition inhibition NN cord-022526-j9kg00qf 1444 7 of of IN cord-022526-j9kg00qf 1444 8 motility motility NN cord-022526-j9kg00qf 1444 9 associated associate VBN cord-022526-j9kg00qf 1444 10 with with IN cord-022526-j9kg00qf 1444 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 1444 12 inflammation inflammation NN cord-022526-j9kg00qf 1444 13 . . . cord-022526-j9kg00qf 1445 1 26 26 CD cord-022526-j9kg00qf 1445 2 , , , cord-022526-j9kg00qf 1445 3 27 27 CD cord-022526-j9kg00qf 1446 1 The the DT cord-022526-j9kg00qf 1446 2 afferent afferent JJ cord-022526-j9kg00qf 1446 3 segment segment NN cord-022526-j9kg00qf 1446 4 is be VBZ cord-022526-j9kg00qf 1446 5 composed compose VBN cord-022526-j9kg00qf 1446 6 partly partly RB cord-022526-j9kg00qf 1446 7 of of IN cord-022526-j9kg00qf 1446 8 capsaicin capsaicin NN cord-022526-j9kg00qf 1446 9 - - HYPH cord-022526-j9kg00qf 1446 10 sensitive sensitive JJ cord-022526-j9kg00qf 1446 11 visceral visceral JJ cord-022526-j9kg00qf 1446 12 afferent afferent NN cord-022526-j9kg00qf 1446 13 C c NN cord-022526-j9kg00qf 1446 14 fibers fiber NNS cord-022526-j9kg00qf 1446 15 that that WDT cord-022526-j9kg00qf 1446 16 terminate terminate VBP cord-022526-j9kg00qf 1446 17 in in IN cord-022526-j9kg00qf 1446 18 the the DT cord-022526-j9kg00qf 1446 19 dorsal dorsal JJ cord-022526-j9kg00qf 1446 20 horn horn NN cord-022526-j9kg00qf 1446 21 of of IN cord-022526-j9kg00qf 1446 22 the the DT cord-022526-j9kg00qf 1446 23 spinal spinal JJ cord-022526-j9kg00qf 1446 24 cord cord NN cord-022526-j9kg00qf 1446 25 , , , cord-022526-j9kg00qf 1446 26 where where WRB cord-022526-j9kg00qf 1446 27 they -PRON- PRP cord-022526-j9kg00qf 1446 28 can can MD cord-022526-j9kg00qf 1446 29 activate activate VB cord-022526-j9kg00qf 1446 30 inhibitory inhibitory JJ cord-022526-j9kg00qf 1446 31 sympathetic sympathetic JJ cord-022526-j9kg00qf 1446 32 fibers fiber NNS cord-022526-j9kg00qf 1446 33 or or CC cord-022526-j9kg00qf 1446 34 synapse synapse NN cord-022526-j9kg00qf 1446 35 directly directly RB cord-022526-j9kg00qf 1446 36 on on IN cord-022526-j9kg00qf 1446 37 the the DT cord-022526-j9kg00qf 1446 38 sympathetic sympathetic JJ cord-022526-j9kg00qf 1446 39 ganglia ganglion NNS cord-022526-j9kg00qf 1446 40 . . . cord-022526-j9kg00qf 1447 1 Consequently consequently RB cord-022526-j9kg00qf 1447 2 , , , cord-022526-j9kg00qf 1447 3 the the DT cord-022526-j9kg00qf 1447 4 efferent efferent JJ cord-022526-j9kg00qf 1447 5 limb limb NN cord-022526-j9kg00qf 1447 6 of of IN cord-022526-j9kg00qf 1447 7 the the DT cord-022526-j9kg00qf 1447 8 reflex reflex NN cord-022526-j9kg00qf 1447 9 expresses express VBZ cord-022526-j9kg00qf 1447 10 increased increase VBN cord-022526-j9kg00qf 1447 11 sympathetic sympathetic JJ cord-022526-j9kg00qf 1447 12 outflow outflow NN cord-022526-j9kg00qf 1447 13 , , , cord-022526-j9kg00qf 1447 14 primarily primarily RB cord-022526-j9kg00qf 1447 15 mediated mediate VBN cord-022526-j9kg00qf 1447 16 through through IN cord-022526-j9kg00qf 1447 17 stimulation stimulation NN cord-022526-j9kg00qf 1447 18 of of IN cord-022526-j9kg00qf 1447 19 α α NN cord-022526-j9kg00qf 1447 20 2 2 CD cord-022526-j9kg00qf 1447 21 -adrenoreceptors -adrenoreceptor NNS cord-022526-j9kg00qf 1447 22 , , , cord-022526-j9kg00qf 1447 23 and and CC cord-022526-j9kg00qf 1447 24 inhibition inhibition NN cord-022526-j9kg00qf 1447 25 of of IN cord-022526-j9kg00qf 1447 26 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1447 27 release release NN cord-022526-j9kg00qf 1447 28 , , , cord-022526-j9kg00qf 1447 29 which which WDT cord-022526-j9kg00qf 1447 30 provides provide VBZ cord-022526-j9kg00qf 1447 31 the the DT cord-022526-j9kg00qf 1447 32 rationale rationale NN cord-022526-j9kg00qf 1447 33 for for IN cord-022526-j9kg00qf 1447 34 α α NN cord-022526-j9kg00qf 1447 35 2 2 CD cord-022526-j9kg00qf 1447 36 -blockade -blockade SYM cord-022526-j9kg00qf 1447 37 in in IN cord-022526-j9kg00qf 1447 38 treating treat VBG cord-022526-j9kg00qf 1447 39 ileus ileus NN cord-022526-j9kg00qf 1447 40 . . . cord-022526-j9kg00qf 1448 1 Intraluminal intraluminal JJ cord-022526-j9kg00qf 1448 2 infusion infusion NN cord-022526-j9kg00qf 1448 3 of of IN cord-022526-j9kg00qf 1448 4 capsaicin capsaicin NNS cord-022526-j9kg00qf 1448 5 before before IN cord-022526-j9kg00qf 1448 6 abdominal abdominal JJ cord-022526-j9kg00qf 1448 7 surgery surgery NN cord-022526-j9kg00qf 1448 8 ameliorated ameliorate VBD cord-022526-j9kg00qf 1448 9 the the DT cord-022526-j9kg00qf 1448 10 severity severity NN cord-022526-j9kg00qf 1448 11 of of IN cord-022526-j9kg00qf 1448 12 POI POI NNP cord-022526-j9kg00qf 1448 13 in in IN cord-022526-j9kg00qf 1448 14 experimental experimental JJ cord-022526-j9kg00qf 1448 15 rats rat NNS cord-022526-j9kg00qf 1448 16 . . . cord-022526-j9kg00qf 1449 1 This this DT cord-022526-j9kg00qf 1449 2 finding finding NN cord-022526-j9kg00qf 1449 3 highlights highlight VBZ cord-022526-j9kg00qf 1449 4 the the DT cord-022526-j9kg00qf 1449 5 importance importance NN cord-022526-j9kg00qf 1449 6 of of IN cord-022526-j9kg00qf 1449 7 visceral visceral JJ cord-022526-j9kg00qf 1449 8 afferent afferent JJ cord-022526-j9kg00qf 1449 9 fibers fiber NNS cord-022526-j9kg00qf 1449 10 in in IN cord-022526-j9kg00qf 1449 11 the the DT cord-022526-j9kg00qf 1449 12 development development NN cord-022526-j9kg00qf 1449 13 of of IN cord-022526-j9kg00qf 1449 14 POI POI NNP cord-022526-j9kg00qf 1449 15 . . . cord-022526-j9kg00qf 1450 1 28 28 CD cord-022526-j9kg00qf 1450 2 Ileus Ileus NNP cord-022526-j9kg00qf 1450 3 also also RB cord-022526-j9kg00qf 1450 4 can can MD cord-022526-j9kg00qf 1450 5 occur occur VB cord-022526-j9kg00qf 1450 6 in in IN cord-022526-j9kg00qf 1450 7 association association NN cord-022526-j9kg00qf 1450 8 with with IN cord-022526-j9kg00qf 1450 9 intestinal intestinal JJ cord-022526-j9kg00qf 1450 10 obstruction obstruction NN cord-022526-j9kg00qf 1450 11 or or CC cord-022526-j9kg00qf 1450 12 displacement displacement NN cord-022526-j9kg00qf 1450 13 . . . cord-022526-j9kg00qf 1451 1 Mild mild JJ cord-022526-j9kg00qf 1451 2 to to IN cord-022526-j9kg00qf 1451 3 moderate moderate JJ cord-022526-j9kg00qf 1451 4 distention distention NN cord-022526-j9kg00qf 1451 5 of of IN cord-022526-j9kg00qf 1451 6 the the DT cord-022526-j9kg00qf 1451 7 bowel bowel NN cord-022526-j9kg00qf 1451 8 , , , cord-022526-j9kg00qf 1451 9 such such JJ cord-022526-j9kg00qf 1451 10 as as IN cord-022526-j9kg00qf 1451 11 that that DT cord-022526-j9kg00qf 1451 12 occurring occur VBG cord-022526-j9kg00qf 1451 13 in in IN cord-022526-j9kg00qf 1451 14 the the DT cord-022526-j9kg00qf 1451 15 early early JJ cord-022526-j9kg00qf 1451 16 stages stage NNS cord-022526-j9kg00qf 1451 17 of of IN cord-022526-j9kg00qf 1451 18 an an DT cord-022526-j9kg00qf 1451 19 intraluminal intraluminal JJ cord-022526-j9kg00qf 1451 20 obstruction obstruction NN cord-022526-j9kg00qf 1451 21 , , , cord-022526-j9kg00qf 1451 22 evokes evoke VBZ cord-022526-j9kg00qf 1451 23 an an DT cord-022526-j9kg00qf 1451 24 increase increase NN cord-022526-j9kg00qf 1451 25 in in IN cord-022526-j9kg00qf 1451 26 local local JJ cord-022526-j9kg00qf 1451 27 contractile contractile JJ cord-022526-j9kg00qf 1451 28 activity activity NN cord-022526-j9kg00qf 1451 29 . . . cord-022526-j9kg00qf 1452 1 29 29 CD cord-022526-j9kg00qf 1452 2 , , , cord-022526-j9kg00qf 1452 3 30 30 CD cord-022526-j9kg00qf 1452 4 Excessive excessive JJ cord-022526-j9kg00qf 1452 5 distention distention NN cord-022526-j9kg00qf 1452 6 results result NNS cord-022526-j9kg00qf 1452 7 in in IN cord-022526-j9kg00qf 1452 8 inhibition inhibition NN cord-022526-j9kg00qf 1452 9 of of IN cord-022526-j9kg00qf 1452 10 motility motility NN cord-022526-j9kg00qf 1452 11 within within IN cord-022526-j9kg00qf 1452 12 the the DT cord-022526-j9kg00qf 1452 13 distended distended JJ cord-022526-j9kg00qf 1452 14 segment segment NN cord-022526-j9kg00qf 1452 15 of of IN cord-022526-j9kg00qf 1452 16 bowel bowel NN cord-022526-j9kg00qf 1452 17 . . . cord-022526-j9kg00qf 1453 1 Intestinal intestinal JJ cord-022526-j9kg00qf 1453 2 stasis stasis NN cord-022526-j9kg00qf 1453 3 is be VBZ cord-022526-j9kg00qf 1453 4 not not RB cord-022526-j9kg00qf 1453 5 always always RB cord-022526-j9kg00qf 1453 6 detrimental detrimental JJ cord-022526-j9kg00qf 1453 7 and and CC cord-022526-j9kg00qf 1453 8 under under IN cord-022526-j9kg00qf 1453 9 certain certain JJ cord-022526-j9kg00qf 1453 10 conditions condition NNS cord-022526-j9kg00qf 1453 11 may may MD cord-022526-j9kg00qf 1453 12 be be VB cord-022526-j9kg00qf 1453 13 protective protective JJ cord-022526-j9kg00qf 1453 14 . . . cord-022526-j9kg00qf 1454 1 Endotoxemia Endotoxemia NNP cord-022526-j9kg00qf 1454 2 is be VBZ cord-022526-j9kg00qf 1454 3 a a DT cord-022526-j9kg00qf 1454 4 clinical clinical JJ cord-022526-j9kg00qf 1454 5 feature feature NN cord-022526-j9kg00qf 1454 6 of of IN cord-022526-j9kg00qf 1454 7 many many JJ cord-022526-j9kg00qf 1454 8 diseases disease NNS cord-022526-j9kg00qf 1454 9 of of IN cord-022526-j9kg00qf 1454 10 the the DT cord-022526-j9kg00qf 1454 11 equine equine JJ cord-022526-j9kg00qf 1454 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1454 13 tract tract NN cord-022526-j9kg00qf 1454 14 , , , cord-022526-j9kg00qf 1454 15 and and CC cord-022526-j9kg00qf 1454 16 endotoxins endotoxin NNS cord-022526-j9kg00qf 1454 17 independently independently RB cord-022526-j9kg00qf 1454 18 can can MD cord-022526-j9kg00qf 1454 19 exert exert VB cord-022526-j9kg00qf 1454 20 a a DT cord-022526-j9kg00qf 1454 21 negative negative JJ cord-022526-j9kg00qf 1454 22 effect effect NN cord-022526-j9kg00qf 1454 23 on on IN cord-022526-j9kg00qf 1454 24 intestinal intestinal JJ cord-022526-j9kg00qf 1454 25 motility motility NN cord-022526-j9kg00qf 1454 26 and and CC cord-022526-j9kg00qf 1454 27 transit transit NN cord-022526-j9kg00qf 1454 28 . . . cord-022526-j9kg00qf 1455 1 31 31 CD cord-022526-j9kg00qf 1456 1 A a DT cord-022526-j9kg00qf 1456 2 variety variety NN cord-022526-j9kg00qf 1456 3 of of IN cord-022526-j9kg00qf 1456 4 mediators mediator NNS cord-022526-j9kg00qf 1456 5 likely likely RB cord-022526-j9kg00qf 1456 6 are be VBP cord-022526-j9kg00qf 1456 7 involved involve VBN cord-022526-j9kg00qf 1456 8 , , , cord-022526-j9kg00qf 1456 9 but but CC cord-022526-j9kg00qf 1456 10 activation activation NN cord-022526-j9kg00qf 1456 11 of of IN cord-022526-j9kg00qf 1456 12 α α NN cord-022526-j9kg00qf 1456 13 2 2 CD cord-022526-j9kg00qf 1456 14 -adrenoreceptors -adrenoreceptor NNS cord-022526-j9kg00qf 1456 15 and and CC cord-022526-j9kg00qf 1456 16 production production NN cord-022526-j9kg00qf 1456 17 of of IN cord-022526-j9kg00qf 1456 18 prostanoids prostanoid NNS cord-022526-j9kg00qf 1456 19 appear appear VBP cord-022526-j9kg00qf 1456 20 to to TO cord-022526-j9kg00qf 1456 21 be be VB cord-022526-j9kg00qf 1456 22 important important JJ cord-022526-j9kg00qf 1456 23 , , , cord-022526-j9kg00qf 1456 24 for for IN cord-022526-j9kg00qf 1456 25 pretreatment pretreatment NN cord-022526-j9kg00qf 1456 26 with with IN cord-022526-j9kg00qf 1456 27 yohimbine yohimbine NN cord-022526-j9kg00qf 1456 28 or or CC cord-022526-j9kg00qf 1456 29 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 1456 30 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1456 31 drugs drug NNS cord-022526-j9kg00qf 1456 32 ( ( -LRB- cord-022526-j9kg00qf 1456 33 NSAIDs nsaid NNS cord-022526-j9kg00qf 1456 34 ; ; : cord-022526-j9kg00qf 1456 35 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 1456 36 or or CC cord-022526-j9kg00qf 1456 37 flunixin flunixin NNP cord-022526-j9kg00qf 1456 38 ) ) -RRB- cord-022526-j9kg00qf 1456 39 , , , cord-022526-j9kg00qf 1456 40 respectively respectively RB cord-022526-j9kg00qf 1456 41 , , , cord-022526-j9kg00qf 1456 42 ameliorates ameliorate VBZ cord-022526-j9kg00qf 1456 43 the the DT cord-022526-j9kg00qf 1456 44 inhibitory inhibitory JJ cord-022526-j9kg00qf 1456 45 effects effect NNS cord-022526-j9kg00qf 1456 46 of of IN cord-022526-j9kg00qf 1456 47 experimental experimental JJ cord-022526-j9kg00qf 1456 48 endotoxin endotoxin NN cord-022526-j9kg00qf 1456 49 infusion infusion NN cord-022526-j9kg00qf 1456 50 . . . cord-022526-j9kg00qf 1457 1 32 32 CD cord-022526-j9kg00qf 1457 2 , , , cord-022526-j9kg00qf 1457 3 33 33 CD cord-022526-j9kg00qf 1457 4 Endotoxin endotoxin NN cord-022526-j9kg00qf 1457 5 infusion infusion NN cord-022526-j9kg00qf 1457 6 induced induce VBD cord-022526-j9kg00qf 1457 7 an an DT cord-022526-j9kg00qf 1457 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 1457 9 response response NN cord-022526-j9kg00qf 1457 10 in in IN cord-022526-j9kg00qf 1457 11 the the DT cord-022526-j9kg00qf 1457 12 intestine intestine NN cord-022526-j9kg00qf 1457 13 of of IN cord-022526-j9kg00qf 1457 14 rats rat NNS cord-022526-j9kg00qf 1457 15 that that WDT cord-022526-j9kg00qf 1457 16 mimicked mimic VBD cord-022526-j9kg00qf 1457 17 the the DT cord-022526-j9kg00qf 1457 18 response response NN cord-022526-j9kg00qf 1457 19 induced induce VBN cord-022526-j9kg00qf 1457 20 by by IN cord-022526-j9kg00qf 1457 21 handling handle VBG cord-022526-j9kg00qf 1457 22 during during IN cord-022526-j9kg00qf 1457 23 laparotomy laparotomy NN cord-022526-j9kg00qf 1457 24 . . . cord-022526-j9kg00qf 1458 1 34 34 CD cord-022526-j9kg00qf 1459 1 The the DT cord-022526-j9kg00qf 1459 2 similarity similarity NN cord-022526-j9kg00qf 1459 3 of of IN cord-022526-j9kg00qf 1459 4 the the DT cord-022526-j9kg00qf 1459 5 responses response NNS cord-022526-j9kg00qf 1459 6 were be VBD cord-022526-j9kg00qf 1459 7 highlighted highlight VBN cord-022526-j9kg00qf 1459 8 in in IN cord-022526-j9kg00qf 1459 9 a a DT cord-022526-j9kg00qf 1459 10 recent recent JJ cord-022526-j9kg00qf 1459 11 study study NN cord-022526-j9kg00qf 1459 12 that that WDT cord-022526-j9kg00qf 1459 13 demonstrated demonstrate VBD cord-022526-j9kg00qf 1459 14 that that IN cord-022526-j9kg00qf 1459 15 prior prior JJ cord-022526-j9kg00qf 1459 16 exposure exposure NN cord-022526-j9kg00qf 1459 17 of of IN cord-022526-j9kg00qf 1459 18 the the DT cord-022526-j9kg00qf 1459 19 muscularis muscularis NN cord-022526-j9kg00qf 1459 20 to to TO cord-022526-j9kg00qf 1459 21 endotoxin endotoxin VB cord-022526-j9kg00qf 1459 22 protected protect VBN cord-022526-j9kg00qf 1459 23 the the DT cord-022526-j9kg00qf 1459 24 intestine intestine NN cord-022526-j9kg00qf 1459 25 from from IN cord-022526-j9kg00qf 1459 26 the the DT cord-022526-j9kg00qf 1459 27 effects effect NNS cord-022526-j9kg00qf 1459 28 of of IN cord-022526-j9kg00qf 1459 29 manipulation manipulation NN cord-022526-j9kg00qf 1459 30 . . . cord-022526-j9kg00qf 1460 1 35 35 CD cord-022526-j9kg00qf 1461 1 The the DT cord-022526-j9kg00qf 1461 2 pathophysiology pathophysiology NN cord-022526-j9kg00qf 1461 3 of of IN cord-022526-j9kg00qf 1461 4 cecal cecal JJ cord-022526-j9kg00qf 1461 5 emptying emptying NN cord-022526-j9kg00qf 1461 6 defect defect NN cord-022526-j9kg00qf 1461 7 is be VBZ cord-022526-j9kg00qf 1461 8 not not RB cord-022526-j9kg00qf 1461 9 known know VBN cord-022526-j9kg00qf 1461 10 . . . cord-022526-j9kg00qf 1462 1 This this DT cord-022526-j9kg00qf 1462 2 syndrome syndrome NN cord-022526-j9kg00qf 1462 3 may may MD cord-022526-j9kg00qf 1462 4 best best RB cord-022526-j9kg00qf 1462 5 mimic mimic VB cord-022526-j9kg00qf 1462 6 POI POI NNP cord-022526-j9kg00qf 1462 7 in in IN cord-022526-j9kg00qf 1462 8 human human JJ cord-022526-j9kg00qf 1462 9 beings being NNS cord-022526-j9kg00qf 1462 10 and and CC cord-022526-j9kg00qf 1462 11 generally generally RB cord-022526-j9kg00qf 1462 12 is be VBZ cord-022526-j9kg00qf 1462 13 considered consider VBN cord-022526-j9kg00qf 1462 14 a a DT cord-022526-j9kg00qf 1462 15 large large JJ cord-022526-j9kg00qf 1462 16 intestinal intestinal JJ cord-022526-j9kg00qf 1462 17 disorder disorder NN cord-022526-j9kg00qf 1462 18 . . . cord-022526-j9kg00qf 1463 1 An an DT cord-022526-j9kg00qf 1463 2 important important JJ cord-022526-j9kg00qf 1463 3 difference difference NN cord-022526-j9kg00qf 1463 4 in in IN cord-022526-j9kg00qf 1463 5 horses horse NNS cord-022526-j9kg00qf 1463 6 is be VBZ cord-022526-j9kg00qf 1463 7 that that DT cord-022526-j9kg00qf 1463 8 laparotomy laparotomy NN cord-022526-j9kg00qf 1463 9 is be VBZ cord-022526-j9kg00qf 1463 10 a a DT cord-022526-j9kg00qf 1463 11 rare rare JJ cord-022526-j9kg00qf 1463 12 predisposing predisposing NN cord-022526-j9kg00qf 1463 13 factor factor NN cord-022526-j9kg00qf 1463 14 , , , cord-022526-j9kg00qf 1463 15 and and CC cord-022526-j9kg00qf 1463 16 most most JJS cord-022526-j9kg00qf 1463 17 cases case NNS cord-022526-j9kg00qf 1463 18 occur occur VBP cord-022526-j9kg00qf 1463 19 in in IN cord-022526-j9kg00qf 1463 20 horses horse NNS cord-022526-j9kg00qf 1463 21 undergoing undergo VBG cord-022526-j9kg00qf 1463 22 routine routine JJ cord-022526-j9kg00qf 1463 23 extraabdominal extraabdominal JJ cord-022526-j9kg00qf 1463 24 surgical surgical JJ cord-022526-j9kg00qf 1463 25 procedures procedure NNS cord-022526-j9kg00qf 1463 26 . . . cord-022526-j9kg00qf 1464 1 General general JJ cord-022526-j9kg00qf 1464 2 anesthesia anesthesia NN cord-022526-j9kg00qf 1464 3 itself -PRON- PRP cord-022526-j9kg00qf 1464 4 is be VBZ cord-022526-j9kg00qf 1464 5 a a DT cord-022526-j9kg00qf 1464 6 potent potent JJ cord-022526-j9kg00qf 1464 7 inhibitor inhibitor NN cord-022526-j9kg00qf 1464 8 of of IN cord-022526-j9kg00qf 1464 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1464 10 motility motility NN cord-022526-j9kg00qf 1464 11 in in IN cord-022526-j9kg00qf 1464 12 horses horse NNS cord-022526-j9kg00qf 1464 13 , , , cord-022526-j9kg00qf 1464 14 but but CC cord-022526-j9kg00qf 1464 15 these these DT cord-022526-j9kg00qf 1464 16 effects effect NNS cord-022526-j9kg00qf 1464 17 are be VBP cord-022526-j9kg00qf 1464 18 short short RB cord-022526-j9kg00qf 1464 19 - - HYPH cord-022526-j9kg00qf 1464 20 lived live VBN cord-022526-j9kg00qf 1464 21 and and CC cord-022526-j9kg00qf 1464 22 reversible reversible JJ cord-022526-j9kg00qf 1464 23 within within IN cord-022526-j9kg00qf 1464 24 hours hour NNS cord-022526-j9kg00qf 1464 25 of of IN cord-022526-j9kg00qf 1464 26 anesthetic anesthetic JJ cord-022526-j9kg00qf 1464 27 withdrawal withdrawal NN cord-022526-j9kg00qf 1464 28 . . . cord-022526-j9kg00qf 1465 1 15 15 CD cord-022526-j9kg00qf 1466 1 The the DT cord-022526-j9kg00qf 1466 2 return return NN cord-022526-j9kg00qf 1466 3 of of IN cord-022526-j9kg00qf 1466 4 normal normal JJ cord-022526-j9kg00qf 1466 5 motility motility NN cord-022526-j9kg00qf 1466 6 in in IN cord-022526-j9kg00qf 1466 7 horses horse NNS cord-022526-j9kg00qf 1466 8 after after IN cord-022526-j9kg00qf 1466 9 experimental experimental JJ cord-022526-j9kg00qf 1466 10 ileus ileus NN cord-022526-j9kg00qf 1466 11 was be VBD cord-022526-j9kg00qf 1466 12 most most RBS cord-022526-j9kg00qf 1466 13 delayed delay VBN cord-022526-j9kg00qf 1466 14 in in IN cord-022526-j9kg00qf 1466 15 the the DT cord-022526-j9kg00qf 1466 16 cecum cecum NN cord-022526-j9kg00qf 1466 17 , , , cord-022526-j9kg00qf 1466 18 suggesting suggest VBG cord-022526-j9kg00qf 1466 19 that that IN cord-022526-j9kg00qf 1466 20 this this DT cord-022526-j9kg00qf 1466 21 may may MD cord-022526-j9kg00qf 1466 22 be be VB cord-022526-j9kg00qf 1466 23 a a DT cord-022526-j9kg00qf 1466 24 common common JJ cord-022526-j9kg00qf 1466 25 site site NN cord-022526-j9kg00qf 1466 26 of of IN cord-022526-j9kg00qf 1466 27 ileus ileus NN cord-022526-j9kg00qf 1466 28 in in IN cord-022526-j9kg00qf 1466 29 horses horse NNS cord-022526-j9kg00qf 1466 30 . . . cord-022526-j9kg00qf 1467 1 36 36 CD cord-022526-j9kg00qf 1468 1 A a DT cord-022526-j9kg00qf 1468 2 link link NN cord-022526-j9kg00qf 1468 3 between between IN cord-022526-j9kg00qf 1468 4 routine routine JJ cord-022526-j9kg00qf 1468 5 postoperative postoperative JJ cord-022526-j9kg00qf 1468 6 medications medication NNS cord-022526-j9kg00qf 1468 7 , , , cord-022526-j9kg00qf 1468 8 such such JJ cord-022526-j9kg00qf 1468 9 as as IN cord-022526-j9kg00qf 1468 10 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 1468 11 and and CC cord-022526-j9kg00qf 1468 12 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 1468 13 antibiotics antibiotic NNS cord-022526-j9kg00qf 1468 14 , , , cord-022526-j9kg00qf 1468 15 has have VBZ cord-022526-j9kg00qf 1468 16 been be VBN cord-022526-j9kg00qf 1468 17 suspected suspect VBN cord-022526-j9kg00qf 1468 18 but but CC cord-022526-j9kg00qf 1468 19 not not RB cord-022526-j9kg00qf 1468 20 established establish VBN cord-022526-j9kg00qf 1468 21 . . . cord-022526-j9kg00qf 1469 1 An an DT cord-022526-j9kg00qf 1469 2 inhibitory inhibitory JJ cord-022526-j9kg00qf 1469 3 effect effect NN cord-022526-j9kg00qf 1469 4 of of IN cord-022526-j9kg00qf 1469 5 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 1469 6 on on IN cord-022526-j9kg00qf 1469 7 large large JJ cord-022526-j9kg00qf 1469 8 colon colon NN cord-022526-j9kg00qf 1469 9 contractility contractility NN cord-022526-j9kg00qf 1469 10 has have VBZ cord-022526-j9kg00qf 1469 11 been be VBN cord-022526-j9kg00qf 1469 12 demonstrated demonstrate VBN cord-022526-j9kg00qf 1469 13 using use VBG cord-022526-j9kg00qf 1469 14 in in IN cord-022526-j9kg00qf 1469 15 vitro vitro FW cord-022526-j9kg00qf 1469 16 techniques technique NNS cord-022526-j9kg00qf 1469 17 . . . cord-022526-j9kg00qf 1470 1 37 37 CD cord-022526-j9kg00qf 1470 2 Primary primary JJ cord-022526-j9kg00qf 1470 3 sympathetic sympathetic JJ cord-022526-j9kg00qf 1470 4 overstimulation overstimulation NN cord-022526-j9kg00qf 1470 5 could could MD cord-022526-j9kg00qf 1470 6 be be VB cord-022526-j9kg00qf 1470 7 involved involve VBN cord-022526-j9kg00qf 1470 8 , , , cord-022526-j9kg00qf 1470 9 for for IN cord-022526-j9kg00qf 1470 10 many many JJ cord-022526-j9kg00qf 1470 11 of of IN cord-022526-j9kg00qf 1470 12 the the DT cord-022526-j9kg00qf 1470 13 affected affect VBN cord-022526-j9kg00qf 1470 14 animals animal NNS cord-022526-j9kg00qf 1470 15 are be VBP cord-022526-j9kg00qf 1470 16 young young JJ cord-022526-j9kg00qf 1470 17 , , , cord-022526-j9kg00qf 1470 18 male male JJ cord-022526-j9kg00qf 1470 19 horses horse NNS cord-022526-j9kg00qf 1470 20 or or CC cord-022526-j9kg00qf 1470 21 animals animal NNS cord-022526-j9kg00qf 1470 22 with with IN cord-022526-j9kg00qf 1470 23 painful painful JJ cord-022526-j9kg00qf 1470 24 diseases disease NNS cord-022526-j9kg00qf 1470 25 . . . cord-022526-j9kg00qf 1471 1 The the DT cord-022526-j9kg00qf 1471 2 duration duration NN cord-022526-j9kg00qf 1471 3 of of IN cord-022526-j9kg00qf 1471 4 surgery surgery NN cord-022526-j9kg00qf 1471 5 influences influence VBZ cord-022526-j9kg00qf 1471 6 the the DT cord-022526-j9kg00qf 1471 7 development development NN cord-022526-j9kg00qf 1471 8 of of IN cord-022526-j9kg00qf 1471 9 small small JJ cord-022526-j9kg00qf 1471 10 intestinal intestinal JJ cord-022526-j9kg00qf 1471 11 POI poi NN cord-022526-j9kg00qf 1471 12 , , , cord-022526-j9kg00qf 1471 13 but but CC cord-022526-j9kg00qf 1471 14 not not RB cord-022526-j9kg00qf 1471 15 cecal cecal JJ cord-022526-j9kg00qf 1471 16 emptying empty VBG cord-022526-j9kg00qf 1471 17 dysfunction dysfunction NN cord-022526-j9kg00qf 1471 18 . . . cord-022526-j9kg00qf 1472 1 7,38 7,38 NNP cord-022526-j9kg00qf 1472 2 Technique Technique NNP cord-022526-j9kg00qf 1472 3 may may MD cord-022526-j9kg00qf 1472 4 have have VB cord-022526-j9kg00qf 1472 5 a a DT cord-022526-j9kg00qf 1472 6 weak weak JJ cord-022526-j9kg00qf 1472 7 influence influence NN cord-022526-j9kg00qf 1472 8 on on IN cord-022526-j9kg00qf 1472 9 small small JJ cord-022526-j9kg00qf 1472 10 intestinal intestinal JJ cord-022526-j9kg00qf 1472 11 POI poi NN cord-022526-j9kg00qf 1472 12 after after IN cord-022526-j9kg00qf 1472 13 jejunojejunostomy jejunojejunostomy NN cord-022526-j9kg00qf 1472 14 . . . cord-022526-j9kg00qf 1473 1 The the DT cord-022526-j9kg00qf 1473 2 duration duration NN cord-022526-j9kg00qf 1473 3 of of IN cord-022526-j9kg00qf 1473 4 intestinal intestinal JJ cord-022526-j9kg00qf 1473 5 ileus ileus NN cord-022526-j9kg00qf 1473 6 was be VBD cord-022526-j9kg00qf 1473 7 shorter short JJR cord-022526-j9kg00qf 1473 8 in in IN cord-022526-j9kg00qf 1473 9 animals animal NNS cord-022526-j9kg00qf 1473 10 that that WDT cord-022526-j9kg00qf 1473 11 received receive VBD cord-022526-j9kg00qf 1473 12 a a DT cord-022526-j9kg00qf 1473 13 sideto sideto JJ cord-022526-j9kg00qf 1473 14 - - HYPH cord-022526-j9kg00qf 1473 15 side side NN cord-022526-j9kg00qf 1473 16 stapled staple VBD cord-022526-j9kg00qf 1473 17 anastomosis anastomosis NN cord-022526-j9kg00qf 1473 18 than than IN cord-022526-j9kg00qf 1473 19 those those DT cord-022526-j9kg00qf 1473 20 that that WDT cord-022526-j9kg00qf 1473 21 had have VBD cord-022526-j9kg00qf 1473 22 a a DT cord-022526-j9kg00qf 1473 23 hand hand NN cord-022526-j9kg00qf 1473 24 sewn sew VBN cord-022526-j9kg00qf 1473 25 end end NN cord-022526-j9kg00qf 1473 26 - - HYPH cord-022526-j9kg00qf 1473 27 to to IN cord-022526-j9kg00qf 1473 28 - - HYPH cord-022526-j9kg00qf 1473 29 end end NN cord-022526-j9kg00qf 1473 30 procedure procedure NN cord-022526-j9kg00qf 1473 31 . . . cord-022526-j9kg00qf 1474 1 3 3 LS cord-022526-j9kg00qf 1475 1 The the DT cord-022526-j9kg00qf 1475 2 duration duration NN cord-022526-j9kg00qf 1475 3 of of IN cord-022526-j9kg00qf 1475 4 ileus ileus NN cord-022526-j9kg00qf 1475 5 after after IN cord-022526-j9kg00qf 1475 6 stapled staple VBN cord-022526-j9kg00qf 1475 7 end end NN cord-022526-j9kg00qf 1475 8 - - HYPH cord-022526-j9kg00qf 1475 9 to to IN cord-022526-j9kg00qf 1475 10 - - HYPH cord-022526-j9kg00qf 1475 11 end end NN cord-022526-j9kg00qf 1475 12 anastomosis anastomosis NN cord-022526-j9kg00qf 1475 13 was be VBD cord-022526-j9kg00qf 1475 14 not not RB cord-022526-j9kg00qf 1475 15 different different JJ cord-022526-j9kg00qf 1475 16 from from IN cord-022526-j9kg00qf 1475 17 that that DT cord-022526-j9kg00qf 1475 18 after after IN cord-022526-j9kg00qf 1475 19 either either DT cord-022526-j9kg00qf 1475 20 procedure procedure NN cord-022526-j9kg00qf 1475 21 . . . cord-022526-j9kg00qf 1476 1 Reported report VBN cord-022526-j9kg00qf 1476 2 risk risk NN cord-022526-j9kg00qf 1476 3 factors factor NNS cord-022526-j9kg00qf 1476 4 for for IN cord-022526-j9kg00qf 1476 5 the the DT cord-022526-j9kg00qf 1476 6 development development NN cord-022526-j9kg00qf 1476 7 of of IN cord-022526-j9kg00qf 1476 8 POI POI NNP cord-022526-j9kg00qf 1476 9 in in IN cord-022526-j9kg00qf 1476 10 horses horse NNS cord-022526-j9kg00qf 1476 11 include include VBP cord-022526-j9kg00qf 1476 12 age age NN cord-022526-j9kg00qf 1476 13 ( ( -LRB- cord-022526-j9kg00qf 1476 14 > > NFP cord-022526-j9kg00qf 1476 15 10 10 CD cord-022526-j9kg00qf 1476 16 years year NNS cord-022526-j9kg00qf 1476 17 ) ) -RRB- cord-022526-j9kg00qf 1476 18 , , , cord-022526-j9kg00qf 1476 19 small small JJ cord-022526-j9kg00qf 1476 20 intestinal intestinal JJ cord-022526-j9kg00qf 1476 21 resection resection NN cord-022526-j9kg00qf 1476 22 and and CC cord-022526-j9kg00qf 1476 23 anastomosis anastomosis NN cord-022526-j9kg00qf 1476 24 , , , cord-022526-j9kg00qf 1476 25 breed breed NN cord-022526-j9kg00qf 1476 26 ( ( -LRB- cord-022526-j9kg00qf 1476 27 Arabians Arabians NNPS cord-022526-j9kg00qf 1476 28 had have VBD cord-022526-j9kg00qf 1476 29 a a DT cord-022526-j9kg00qf 1476 30 greatest great JJS cord-022526-j9kg00qf 1476 31 risk risk NN cord-022526-j9kg00qf 1476 32 than than IN cord-022526-j9kg00qf 1476 33 other other JJ cord-022526-j9kg00qf 1476 34 breeds breed NNS cord-022526-j9kg00qf 1476 35 ) ) -RRB- cord-022526-j9kg00qf 1476 36 , , , cord-022526-j9kg00qf 1476 37 and and CC cord-022526-j9kg00qf 1476 38 duration duration NN cord-022526-j9kg00qf 1476 39 of of IN cord-022526-j9kg00qf 1476 40 surgery surgery NN cord-022526-j9kg00qf 1476 41 . . . cord-022526-j9kg00qf 1477 1 38 38 CD cord-022526-j9kg00qf 1478 1 Interestingly interestingly RB cord-022526-j9kg00qf 1478 2 , , , cord-022526-j9kg00qf 1478 3 performing perform VBG cord-022526-j9kg00qf 1478 4 a a DT cord-022526-j9kg00qf 1478 5 pelvic pelvic JJ cord-022526-j9kg00qf 1478 6 flexure flexure NN cord-022526-j9kg00qf 1478 7 enterotomy enterotomy NN cord-022526-j9kg00qf 1478 8 and and CC cord-022526-j9kg00qf 1478 9 emptying empty VBG cord-022526-j9kg00qf 1478 10 the the DT cord-022526-j9kg00qf 1478 11 colon colon NN cord-022526-j9kg00qf 1478 12 had have VBD cord-022526-j9kg00qf 1478 13 a a DT cord-022526-j9kg00qf 1478 14 protective protective JJ cord-022526-j9kg00qf 1478 15 effect effect NN cord-022526-j9kg00qf 1478 16 against against IN cord-022526-j9kg00qf 1478 17 POI POI NNP cord-022526-j9kg00qf 1478 18 . . . cord-022526-j9kg00qf 1479 1 The the DT cord-022526-j9kg00qf 1479 2 diagnosis diagnosis NN cord-022526-j9kg00qf 1479 3 of of IN cord-022526-j9kg00qf 1479 4 ileus ileus NNP cord-022526-j9kg00qf 1479 5 is be VBZ cord-022526-j9kg00qf 1479 6 based base VBN cord-022526-j9kg00qf 1479 7 on on IN cord-022526-j9kg00qf 1479 8 history history NN cord-022526-j9kg00qf 1479 9 and and CC cord-022526-j9kg00qf 1479 10 physical physical JJ cord-022526-j9kg00qf 1479 11 examination examination NN cord-022526-j9kg00qf 1479 12 findings finding NNS cord-022526-j9kg00qf 1479 13 . . . cord-022526-j9kg00qf 1480 1 Important important JJ cord-022526-j9kg00qf 1480 2 tests test NNS cord-022526-j9kg00qf 1480 3 include include VBP cord-022526-j9kg00qf 1480 4 determination determination NN cord-022526-j9kg00qf 1480 5 of of IN cord-022526-j9kg00qf 1480 6 pulse pulse NN cord-022526-j9kg00qf 1480 7 rate rate NN cord-022526-j9kg00qf 1480 8 and and CC cord-022526-j9kg00qf 1480 9 rhythm rhythm NN cord-022526-j9kg00qf 1480 10 , , , cord-022526-j9kg00qf 1480 11 auscultation auscultation NN cord-022526-j9kg00qf 1480 12 and and CC cord-022526-j9kg00qf 1480 13 percussion percussion NN cord-022526-j9kg00qf 1480 14 of of IN cord-022526-j9kg00qf 1480 15 the the DT cord-022526-j9kg00qf 1480 16 abdomen abdomen NN cord-022526-j9kg00qf 1480 17 , , , cord-022526-j9kg00qf 1480 18 rectal rectal JJ cord-022526-j9kg00qf 1480 19 palpation palpation NN cord-022526-j9kg00qf 1480 20 , , , cord-022526-j9kg00qf 1480 21 and and CC cord-022526-j9kg00qf 1480 22 passage passage NN cord-022526-j9kg00qf 1480 23 of of IN cord-022526-j9kg00qf 1480 24 a a DT cord-022526-j9kg00qf 1480 25 nasogastric nasogastric NN cord-022526-j9kg00qf 1480 26 tube tube NN cord-022526-j9kg00qf 1480 27 . . . cord-022526-j9kg00qf 1481 1 A a DT cord-022526-j9kg00qf 1481 2 complete complete JJ cord-022526-j9kg00qf 1481 3 blood blood NN cord-022526-j9kg00qf 1481 4 count count NN cord-022526-j9kg00qf 1481 5 with with IN cord-022526-j9kg00qf 1481 6 fibrinogen fibrinogen NN cord-022526-j9kg00qf 1481 7 estimation estimation NN cord-022526-j9kg00qf 1481 8 and and CC cord-022526-j9kg00qf 1481 9 cytologic cytologic JJ cord-022526-j9kg00qf 1481 10 analysis analysis NN cord-022526-j9kg00qf 1481 11 of of IN cord-022526-j9kg00qf 1481 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 1481 13 fluid fluid NN cord-022526-j9kg00qf 1481 14 may may MD cord-022526-j9kg00qf 1481 15 improve improve VB cord-022526-j9kg00qf 1481 16 the the DT cord-022526-j9kg00qf 1481 17 accuracy accuracy NN cord-022526-j9kg00qf 1481 18 of of IN cord-022526-j9kg00qf 1481 19 diagnosis diagnosis NN cord-022526-j9kg00qf 1481 20 . . . cord-022526-j9kg00qf 1482 1 Affected affected JJ cord-022526-j9kg00qf 1482 2 animals animal NNS cord-022526-j9kg00qf 1482 3 may may MD cord-022526-j9kg00qf 1482 4 be be VB cord-022526-j9kg00qf 1482 5 colicky colicky JJ cord-022526-j9kg00qf 1482 6 because because IN cord-022526-j9kg00qf 1482 7 of of IN cord-022526-j9kg00qf 1482 8 accumulation accumulation NN cord-022526-j9kg00qf 1482 9 of of IN cord-022526-j9kg00qf 1482 10 fluid fluid NN cord-022526-j9kg00qf 1482 11 in in IN cord-022526-j9kg00qf 1482 12 the the DT cord-022526-j9kg00qf 1482 13 upper upper JJ cord-022526-j9kg00qf 1482 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1482 15 tract tract NN cord-022526-j9kg00qf 1482 16 ( ( -LRB- cord-022526-j9kg00qf 1482 17 classical classical JJ cord-022526-j9kg00qf 1482 18 POI poi NN cord-022526-j9kg00qf 1482 19 ) ) -RRB- cord-022526-j9kg00qf 1482 20 or or CC cord-022526-j9kg00qf 1482 21 cecal cecal JJ cord-022526-j9kg00qf 1482 22 contents content NNS cord-022526-j9kg00qf 1482 23 ( ( -LRB- cord-022526-j9kg00qf 1482 24 cecal cecal JJ cord-022526-j9kg00qf 1482 25 emptying emptying NN cord-022526-j9kg00qf 1482 26 defect defect NN cord-022526-j9kg00qf 1482 27 ) ) -RRB- cord-022526-j9kg00qf 1482 28 . . . cord-022526-j9kg00qf 1483 1 Decompression decompression NN cord-022526-j9kg00qf 1483 2 of of IN cord-022526-j9kg00qf 1483 3 the the DT cord-022526-j9kg00qf 1483 4 stomach stomach NN cord-022526-j9kg00qf 1483 5 is be VBZ cord-022526-j9kg00qf 1483 6 important important JJ cord-022526-j9kg00qf 1483 7 diagnostically diagnostically RB cord-022526-j9kg00qf 1483 8 and and CC cord-022526-j9kg00qf 1483 9 therapeutically therapeutically RB cord-022526-j9kg00qf 1483 10 in in IN cord-022526-j9kg00qf 1483 11 horses horse NNS cord-022526-j9kg00qf 1483 12 with with IN cord-022526-j9kg00qf 1483 13 POI POI NNP cord-022526-j9kg00qf 1483 14 after after IN cord-022526-j9kg00qf 1483 15 small small JJ cord-022526-j9kg00qf 1483 16 intestinal intestinal JJ cord-022526-j9kg00qf 1483 17 surgery surgery NN cord-022526-j9kg00qf 1483 18 . . . cord-022526-j9kg00qf 1484 1 Failure failure NN cord-022526-j9kg00qf 1484 2 to to TO cord-022526-j9kg00qf 1484 3 relieve relieve VB cord-022526-j9kg00qf 1484 4 pain pain NN cord-022526-j9kg00qf 1484 5 with with IN cord-022526-j9kg00qf 1484 6 gastric gastric JJ cord-022526-j9kg00qf 1484 7 decompression decompression NN cord-022526-j9kg00qf 1484 8 could could MD cord-022526-j9kg00qf 1484 9 point point VB cord-022526-j9kg00qf 1484 10 toward toward IN cord-022526-j9kg00qf 1484 11 mechanical mechanical JJ cord-022526-j9kg00qf 1484 12 obstruction obstruction NN cord-022526-j9kg00qf 1484 13 , , , cord-022526-j9kg00qf 1484 14 severe severe JJ cord-022526-j9kg00qf 1484 15 inflammation inflammation NN cord-022526-j9kg00qf 1484 16 of of IN cord-022526-j9kg00qf 1484 17 the the DT cord-022526-j9kg00qf 1484 18 intestine intestine NN cord-022526-j9kg00qf 1484 19 , , , cord-022526-j9kg00qf 1484 20 or or CC cord-022526-j9kg00qf 1484 21 peritonitis peritonitis NN cord-022526-j9kg00qf 1484 22 . . . cord-022526-j9kg00qf 1485 1 Most Most JJS cord-022526-j9kg00qf 1485 2 animals animal NNS cord-022526-j9kg00qf 1485 3 with with IN cord-022526-j9kg00qf 1485 4 ileus ileus NNP cord-022526-j9kg00qf 1485 5 are be VBP cord-022526-j9kg00qf 1485 6 depressed depressed JJ cord-022526-j9kg00qf 1485 7 and and CC cord-022526-j9kg00qf 1485 8 have have VBP cord-022526-j9kg00qf 1485 9 reduced reduce VBN cord-022526-j9kg00qf 1485 10 fecal fecal JJ cord-022526-j9kg00qf 1485 11 output output NN cord-022526-j9kg00qf 1485 12 and and CC cord-022526-j9kg00qf 1485 13 intestinal intestinal JJ cord-022526-j9kg00qf 1485 14 borborygmi borborygmi NN cord-022526-j9kg00qf 1485 15 . . . cord-022526-j9kg00qf 1486 1 One one PRP cord-022526-j9kg00qf 1486 2 should should MD cord-022526-j9kg00qf 1486 3 interpret interpret VB cord-022526-j9kg00qf 1486 4 intestinal intestinal JJ cord-022526-j9kg00qf 1486 5 sounds sound NNS cord-022526-j9kg00qf 1486 6 with with IN cord-022526-j9kg00qf 1486 7 caution caution NN cord-022526-j9kg00qf 1486 8 , , , cord-022526-j9kg00qf 1486 9 however however RB cord-022526-j9kg00qf 1486 10 , , , cord-022526-j9kg00qf 1486 11 because because IN cord-022526-j9kg00qf 1486 12 the the DT cord-022526-j9kg00qf 1486 13 presence presence NN cord-022526-j9kg00qf 1486 14 of of IN cord-022526-j9kg00qf 1486 15 borborygmi borborygmi NNP cord-022526-j9kg00qf 1486 16 does do VBZ cord-022526-j9kg00qf 1486 17 not not RB cord-022526-j9kg00qf 1486 18 always always RB cord-022526-j9kg00qf 1486 19 equate equate VB cord-022526-j9kg00qf 1486 20 to to IN cord-022526-j9kg00qf 1486 21 progressive progressive JJ cord-022526-j9kg00qf 1486 22 intestinal intestinal JJ cord-022526-j9kg00qf 1486 23 motility motility NN cord-022526-j9kg00qf 1486 24 and and CC cord-022526-j9kg00qf 1486 25 merely merely RB cord-022526-j9kg00qf 1486 26 may may MD cord-022526-j9kg00qf 1486 27 reflect reflect VB cord-022526-j9kg00qf 1486 28 local local JJ cord-022526-j9kg00qf 1486 29 , , , cord-022526-j9kg00qf 1486 30 nonpropagated nonpropagated JJ cord-022526-j9kg00qf 1486 31 contractions contraction NNS cord-022526-j9kg00qf 1486 32 . . . cord-022526-j9kg00qf 1487 1 Rectal rectal JJ cord-022526-j9kg00qf 1487 2 palpation palpation NN cord-022526-j9kg00qf 1487 3 findings finding NNS cord-022526-j9kg00qf 1487 4 in in IN cord-022526-j9kg00qf 1487 5 cases case NNS cord-022526-j9kg00qf 1487 6 of of IN cord-022526-j9kg00qf 1487 7 persistent persistent JJ cord-022526-j9kg00qf 1487 8 POI POI NNP cord-022526-j9kg00qf 1487 9 or or CC cord-022526-j9kg00qf 1487 10 duodenitis duodenitis NN cord-022526-j9kg00qf 1487 11 - - HYPH cord-022526-j9kg00qf 1487 12 proximal proximal JJ cord-022526-j9kg00qf 1487 13 jejunitis jejunitis NN cord-022526-j9kg00qf 1487 14 are be VBP cord-022526-j9kg00qf 1487 15 usually usually RB cord-022526-j9kg00qf 1487 16 nonspecific nonspecific JJ cord-022526-j9kg00qf 1487 17 but but CC cord-022526-j9kg00qf 1487 18 may may MD cord-022526-j9kg00qf 1487 19 reveal reveal VB cord-022526-j9kg00qf 1487 20 dilated dilated JJ cord-022526-j9kg00qf 1487 21 , , , cord-022526-j9kg00qf 1487 22 fluid fluid NN cord-022526-j9kg00qf 1487 23 - - HYPH cord-022526-j9kg00qf 1487 24 filled fill VBN cord-022526-j9kg00qf 1487 25 loops loop NNS cord-022526-j9kg00qf 1487 26 of of IN cord-022526-j9kg00qf 1487 27 small small JJ cord-022526-j9kg00qf 1487 28 intestine intestine NN cord-022526-j9kg00qf 1487 29 . . . cord-022526-j9kg00qf 1488 1 The the DT cord-022526-j9kg00qf 1488 2 clinician clinician NN cord-022526-j9kg00qf 1488 3 occasionally occasionally RB cord-022526-j9kg00qf 1488 4 can can MD cord-022526-j9kg00qf 1488 5 palpate palpate VB cord-022526-j9kg00qf 1488 6 roughened roughen VBN cord-022526-j9kg00qf 1488 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 1488 8 surfaces surface NNS cord-022526-j9kg00qf 1488 9 if if IN cord-022526-j9kg00qf 1488 10 peritonitis peritonitis NN cord-022526-j9kg00qf 1488 11 is be VBZ cord-022526-j9kg00qf 1488 12 present present JJ cord-022526-j9kg00qf 1488 13 . . . cord-022526-j9kg00qf 1489 1 One one PRP cord-022526-j9kg00qf 1489 2 can can MD cord-022526-j9kg00qf 1489 3 palpate palpate VB cord-022526-j9kg00qf 1489 4 cecal cecal JJ cord-022526-j9kg00qf 1489 5 distention distention NN cord-022526-j9kg00qf 1489 6 with with IN cord-022526-j9kg00qf 1489 7 digesta digesta NNS cord-022526-j9kg00qf 1489 8 in in IN cord-022526-j9kg00qf 1489 9 horses horse NNS cord-022526-j9kg00qf 1489 10 with with IN cord-022526-j9kg00qf 1489 11 advanced advanced JJ cord-022526-j9kg00qf 1489 12 cecal cecal JJ cord-022526-j9kg00qf 1489 13 dysfunction dysfunction NN cord-022526-j9kg00qf 1489 14 . . . cord-022526-j9kg00qf 1490 1 Distinguishing distinguish VBG cord-022526-j9kg00qf 1490 2 functional functional JJ cord-022526-j9kg00qf 1490 3 ileus ileus NN cord-022526-j9kg00qf 1490 4 from from IN cord-022526-j9kg00qf 1490 5 mechanical mechanical JJ cord-022526-j9kg00qf 1490 6 obstruction obstruction NN cord-022526-j9kg00qf 1490 7 is be VBZ cord-022526-j9kg00qf 1490 8 important important JJ cord-022526-j9kg00qf 1490 9 and and CC cord-022526-j9kg00qf 1490 10 can can MD cord-022526-j9kg00qf 1490 11 be be VB cord-022526-j9kg00qf 1490 12 difficult difficult JJ cord-022526-j9kg00qf 1490 13 , , , cord-022526-j9kg00qf 1490 14 but but CC cord-022526-j9kg00qf 1490 15 horses horse NNS cord-022526-j9kg00qf 1490 16 with with IN cord-022526-j9kg00qf 1490 17 mechanical mechanical JJ cord-022526-j9kg00qf 1490 18 obstruction obstruction NN cord-022526-j9kg00qf 1490 19 typically typically RB cord-022526-j9kg00qf 1490 20 have have VBP cord-022526-j9kg00qf 1490 21 sustained sustain VBN cord-022526-j9kg00qf 1490 22 high high JJ cord-022526-j9kg00qf 1490 23 volumes volume NNS cord-022526-j9kg00qf 1490 24 of of IN cord-022526-j9kg00qf 1490 25 gastric gastric JJ cord-022526-j9kg00qf 1490 26 reflux reflux NN cord-022526-j9kg00qf 1490 27 that that WDT cord-022526-j9kg00qf 1490 28 vary vary VBP cord-022526-j9kg00qf 1490 29 little little JJ cord-022526-j9kg00qf 1490 30 over over IN cord-022526-j9kg00qf 1490 31 time time NN cord-022526-j9kg00qf 1490 32 . . . cord-022526-j9kg00qf 1491 1 The the DT cord-022526-j9kg00qf 1491 2 management management NN cord-022526-j9kg00qf 1491 3 of of IN cord-022526-j9kg00qf 1491 4 intestinal intestinal JJ cord-022526-j9kg00qf 1491 5 ileus ileus NNP cord-022526-j9kg00qf 1491 6 depends depend VBZ cord-022526-j9kg00qf 1491 7 on on IN cord-022526-j9kg00qf 1491 8 the the DT cord-022526-j9kg00qf 1491 9 segment segment NN cord-022526-j9kg00qf 1491 10 of of IN cord-022526-j9kg00qf 1491 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1491 12 tract tract NN cord-022526-j9kg00qf 1491 13 involved involve VBN cord-022526-j9kg00qf 1491 14 . . . cord-022526-j9kg00qf 1492 1 Therapy therapy NN cord-022526-j9kg00qf 1492 2 for for IN cord-022526-j9kg00qf 1492 3 ileus ileus NN cord-022526-j9kg00qf 1492 4 of of IN cord-022526-j9kg00qf 1492 5 the the DT cord-022526-j9kg00qf 1492 6 proximal proximal JJ cord-022526-j9kg00qf 1492 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1492 8 tract tract NN cord-022526-j9kg00qf 1492 9 involves involve VBZ cord-022526-j9kg00qf 1492 10 a a DT cord-022526-j9kg00qf 1492 11 combination combination NN cord-022526-j9kg00qf 1492 12 of of IN cord-022526-j9kg00qf 1492 13 gastric gastric JJ cord-022526-j9kg00qf 1492 14 decompression decompression NN cord-022526-j9kg00qf 1492 15 , , , cord-022526-j9kg00qf 1492 16 fluid fluid NN cord-022526-j9kg00qf 1492 17 and and CC cord-022526-j9kg00qf 1492 18 electrolyte electrolyte JJ cord-022526-j9kg00qf 1492 19 therapy therapy NN cord-022526-j9kg00qf 1492 20 , , , cord-022526-j9kg00qf 1492 21 and and CC cord-022526-j9kg00qf 1492 22 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1492 23 drug drug NN cord-022526-j9kg00qf 1492 24 therapy therapy NN cord-022526-j9kg00qf 1492 25 . . . cord-022526-j9kg00qf 1493 1 Electrolyte electrolyte NN cord-022526-j9kg00qf 1493 2 therapy therapy NN cord-022526-j9kg00qf 1493 3 is be VBZ cord-022526-j9kg00qf 1493 4 critical critical JJ cord-022526-j9kg00qf 1493 5 , , , cord-022526-j9kg00qf 1493 6 particularly particularly RB cord-022526-j9kg00qf 1493 7 for for IN cord-022526-j9kg00qf 1493 8 maintaining maintain VBG cord-022526-j9kg00qf 1493 9 adequate adequate JJ cord-022526-j9kg00qf 1493 10 extracellular extracellular JJ cord-022526-j9kg00qf 1493 11 concentrations concentration NNS cord-022526-j9kg00qf 1493 12 of of IN cord-022526-j9kg00qf 1493 13 potassium potassium NN cord-022526-j9kg00qf 1493 14 , , , cord-022526-j9kg00qf 1493 15 calcium calcium NN cord-022526-j9kg00qf 1493 16 , , , cord-022526-j9kg00qf 1493 17 and and CC cord-022526-j9kg00qf 1493 18 magnesium magnesium NN cord-022526-j9kg00qf 1493 19 . . . cord-022526-j9kg00qf 1494 1 Calculation calculation NN cord-022526-j9kg00qf 1494 2 of of IN cord-022526-j9kg00qf 1494 3 the the DT cord-022526-j9kg00qf 1494 4 volume volume NN cord-022526-j9kg00qf 1494 5 of of IN cord-022526-j9kg00qf 1494 6 fluid fluid NN cord-022526-j9kg00qf 1494 7 to to TO cord-022526-j9kg00qf 1494 8 be be VB cord-022526-j9kg00qf 1494 9 administered administer VBN cord-022526-j9kg00qf 1494 10 should should MD cord-022526-j9kg00qf 1494 11 include include VB cord-022526-j9kg00qf 1494 12 maintenance maintenance NN cord-022526-j9kg00qf 1494 13 requirements requirement NNS cord-022526-j9kg00qf 1494 14 ( ( -LRB- cord-022526-j9kg00qf 1494 15 40 40 CD cord-022526-j9kg00qf 1494 16 to to TO cord-022526-j9kg00qf 1494 17 60 60 CD cord-022526-j9kg00qf 1494 18 ml ml NNS cord-022526-j9kg00qf 1494 19 / / SYM cord-022526-j9kg00qf 1494 20 kg kg NN cord-022526-j9kg00qf 1494 21 / / SYM cord-022526-j9kg00qf 1494 22 day day NN cord-022526-j9kg00qf 1494 23 ) ) -RRB- cord-022526-j9kg00qf 1494 24 plus plus CC cord-022526-j9kg00qf 1494 25 an an DT cord-022526-j9kg00qf 1494 26 estimate estimate NN cord-022526-j9kg00qf 1494 27 of of IN cord-022526-j9kg00qf 1494 28 losses loss NNS cord-022526-j9kg00qf 1494 29 , , , cord-022526-j9kg00qf 1494 30 especially especially RB cord-022526-j9kg00qf 1494 31 those those DT cord-022526-j9kg00qf 1494 32 lost lose VBD cord-022526-j9kg00qf 1494 33 through through IN cord-022526-j9kg00qf 1494 34 gastric gastric JJ cord-022526-j9kg00qf 1494 35 decompression decompression NN cord-022526-j9kg00qf 1494 36 . . . cord-022526-j9kg00qf 1495 1 One one PRP cord-022526-j9kg00qf 1495 2 should should MD cord-022526-j9kg00qf 1495 3 consider consider VB cord-022526-j9kg00qf 1495 4 parenteral parenteral JJ cord-022526-j9kg00qf 1495 5 provision provision NN cord-022526-j9kg00qf 1495 6 of of IN cord-022526-j9kg00qf 1495 7 calories calorie NNS cord-022526-j9kg00qf 1495 8 when when WRB cord-022526-j9kg00qf 1495 9 feed feed NN cord-022526-j9kg00qf 1495 10 has have VBZ cord-022526-j9kg00qf 1495 11 been be VBN cord-022526-j9kg00qf 1495 12 withheld withhold VBN cord-022526-j9kg00qf 1495 13 for for IN cord-022526-j9kg00qf 1495 14 more more JJR cord-022526-j9kg00qf 1495 15 than than IN cord-022526-j9kg00qf 1495 16 96 96 CD cord-022526-j9kg00qf 1495 17 hours hour NNS cord-022526-j9kg00qf 1495 18 , , , cord-022526-j9kg00qf 1495 19 particularly particularly RB cord-022526-j9kg00qf 1495 20 after after IN cord-022526-j9kg00qf 1495 21 the the DT cord-022526-j9kg00qf 1495 22 horse horse NN cord-022526-j9kg00qf 1495 23 has have VBZ cord-022526-j9kg00qf 1495 24 had have VBN cord-022526-j9kg00qf 1495 25 surgery surgery NN cord-022526-j9kg00qf 1495 26 . . . cord-022526-j9kg00qf 1496 1 A a DT cord-022526-j9kg00qf 1496 2 combination combination NN cord-022526-j9kg00qf 1496 3 of of IN cord-022526-j9kg00qf 1496 4 amino amino NN cord-022526-j9kg00qf 1496 5 acids acid NNS cord-022526-j9kg00qf 1496 6 and and CC cord-022526-j9kg00qf 1496 7 dextrose dextrose NN cord-022526-j9kg00qf 1496 8 with with IN cord-022526-j9kg00qf 1496 9 or or CC cord-022526-j9kg00qf 1496 10 without without IN cord-022526-j9kg00qf 1496 11 lipids lipid NNS cord-022526-j9kg00qf 1496 12 effectively effectively RB cord-022526-j9kg00qf 1496 13 provides provide VBZ cord-022526-j9kg00qf 1496 14 these these DT cord-022526-j9kg00qf 1496 15 calories calorie NNS cord-022526-j9kg00qf 1496 16 . . . cord-022526-j9kg00qf 1497 1 Hand hand NN cord-022526-j9kg00qf 1497 2 walking walking NN cord-022526-j9kg00qf 1497 3 also also RB cord-022526-j9kg00qf 1497 4 may may MD cord-022526-j9kg00qf 1497 5 provide provide VB cord-022526-j9kg00qf 1497 6 some some DT cord-022526-j9kg00qf 1497 7 benefit benefit NN cord-022526-j9kg00qf 1497 8 to to IN cord-022526-j9kg00qf 1497 9 these these DT cord-022526-j9kg00qf 1497 10 animals animal NNS cord-022526-j9kg00qf 1497 11 but but CC cord-022526-j9kg00qf 1497 12 is be VBZ cord-022526-j9kg00qf 1497 13 not not RB cord-022526-j9kg00qf 1497 14 likely likely JJ cord-022526-j9kg00qf 1497 15 to to TO cord-022526-j9kg00qf 1497 16 have have VB cord-022526-j9kg00qf 1497 17 a a DT cord-022526-j9kg00qf 1497 18 direct direct JJ cord-022526-j9kg00qf 1497 19 effect effect NN cord-022526-j9kg00qf 1497 20 on on IN cord-022526-j9kg00qf 1497 21 intestinal intestinal JJ cord-022526-j9kg00qf 1497 22 motility motility NN cord-022526-j9kg00qf 1497 23 . . . cord-022526-j9kg00qf 1498 1 One one PRP cord-022526-j9kg00qf 1498 2 should should MD cord-022526-j9kg00qf 1498 3 avoid avoid VB cord-022526-j9kg00qf 1498 4 drugs drug NNS cord-022526-j9kg00qf 1498 5 that that WDT cord-022526-j9kg00qf 1498 6 may may MD cord-022526-j9kg00qf 1498 7 impair impair VB cord-022526-j9kg00qf 1498 8 normal normal JJ cord-022526-j9kg00qf 1498 9 intestinal intestinal JJ cord-022526-j9kg00qf 1498 10 motility motility NN cord-022526-j9kg00qf 1498 11 , , , cord-022526-j9kg00qf 1498 12 including include VBG cord-022526-j9kg00qf 1498 13 the the DT cord-022526-j9kg00qf 1498 14 anticholinergics anticholinergic NNS cord-022526-j9kg00qf 1498 15 such such JJ cord-022526-j9kg00qf 1498 16 as as IN cord-022526-j9kg00qf 1498 17 atropine atropine NN cord-022526-j9kg00qf 1498 18 and and CC cord-022526-j9kg00qf 1498 19 opiate opiate NN cord-022526-j9kg00qf 1498 20 receptor receptor NN cord-022526-j9kg00qf 1498 21 agonists agonist NNS cord-022526-j9kg00qf 1498 22 such such JJ cord-022526-j9kg00qf 1498 23 as as IN cord-022526-j9kg00qf 1498 24 morphine morphine NN cord-022526-j9kg00qf 1498 25 and and CC cord-022526-j9kg00qf 1498 26 meperidine meperidine NN cord-022526-j9kg00qf 1498 27 . . . cord-022526-j9kg00qf 1499 1 Butorphanol Butorphanol NNP cord-022526-j9kg00qf 1499 2 appears appear VBZ cord-022526-j9kg00qf 1499 3 to to TO cord-022526-j9kg00qf 1499 4 have have VB cord-022526-j9kg00qf 1499 5 little little JJ cord-022526-j9kg00qf 1499 6 or or CC cord-022526-j9kg00qf 1499 7 no no DT cord-022526-j9kg00qf 1499 8 adverse adverse JJ cord-022526-j9kg00qf 1499 9 effect effect NN cord-022526-j9kg00qf 1499 10 on on IN cord-022526-j9kg00qf 1499 11 small small JJ cord-022526-j9kg00qf 1499 12 or or CC cord-022526-j9kg00qf 1499 13 large large JJ cord-022526-j9kg00qf 1499 14 intestinal intestinal JJ cord-022526-j9kg00qf 1499 15 motility motility NN cord-022526-j9kg00qf 1499 16 . . . cord-022526-j9kg00qf 1500 1 39 39 CD cord-022526-j9kg00qf 1500 2 , , , cord-022526-j9kg00qf 1500 3 40 40 CD cord-022526-j9kg00qf 1500 4 One one PRP cord-022526-j9kg00qf 1500 5 should should MD cord-022526-j9kg00qf 1500 6 use use VB cord-022526-j9kg00qf 1500 7 α α NN cord-022526-j9kg00qf 1500 8 2 2 CD cord-022526-j9kg00qf 1500 9 -agonists -agonist NNS cord-022526-j9kg00qf 1500 10 sparingly sparingly RB cord-022526-j9kg00qf 1500 11 because because IN cord-022526-j9kg00qf 1500 12 of of IN cord-022526-j9kg00qf 1500 13 their -PRON- PRP$ cord-022526-j9kg00qf 1500 14 inhibitory inhibitory JJ cord-022526-j9kg00qf 1500 15 effects effect NNS cord-022526-j9kg00qf 1500 16 on on IN cord-022526-j9kg00qf 1500 17 large large JJ cord-022526-j9kg00qf 1500 18 intestinal intestinal JJ cord-022526-j9kg00qf 1500 19 motility motility NN cord-022526-j9kg00qf 1500 20 . . . cord-022526-j9kg00qf 1501 1 Fluid fluid JJ cord-022526-j9kg00qf 1501 2 therapy therapy NN cord-022526-j9kg00qf 1501 3 is be VBZ cord-022526-j9kg00qf 1501 4 the the DT cord-022526-j9kg00qf 1501 5 key key JJ cord-022526-j9kg00qf 1501 6 component component NN cord-022526-j9kg00qf 1501 7 in in IN cord-022526-j9kg00qf 1501 8 managing manage VBG cord-022526-j9kg00qf 1501 9 cecal cecal JJ cord-022526-j9kg00qf 1501 10 emptying emptying NN cord-022526-j9kg00qf 1501 11 defect defect NN cord-022526-j9kg00qf 1501 12 , , , cord-022526-j9kg00qf 1501 13 usually usually RB cord-022526-j9kg00qf 1501 14 in in IN cord-022526-j9kg00qf 1501 15 combination combination NN cord-022526-j9kg00qf 1501 16 with with IN cord-022526-j9kg00qf 1501 17 lubricants lubricant NNS cord-022526-j9kg00qf 1501 18 or or CC cord-022526-j9kg00qf 1501 19 laxatives laxative NNS cord-022526-j9kg00qf 1501 20 , , , cord-022526-j9kg00qf 1501 21 such such JJ cord-022526-j9kg00qf 1501 22 as as IN cord-022526-j9kg00qf 1501 23 mineral mineral NN cord-022526-j9kg00qf 1501 24 oil oil NN cord-022526-j9kg00qf 1501 25 or or CC cord-022526-j9kg00qf 1501 26 magnesium magnesium NN cord-022526-j9kg00qf 1501 27 sulfate sulfate NN cord-022526-j9kg00qf 1501 28 , , , cord-022526-j9kg00qf 1501 29 and and CC cord-022526-j9kg00qf 1501 30 with with IN cord-022526-j9kg00qf 1501 31 careful careful JJ cord-022526-j9kg00qf 1501 32 use use NN cord-022526-j9kg00qf 1501 33 of of IN cord-022526-j9kg00qf 1501 34 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1501 35 drugs drug NNS cord-022526-j9kg00qf 1501 36 . . . cord-022526-j9kg00qf 1502 1 Horses horse NNS cord-022526-j9kg00qf 1502 2 with with IN cord-022526-j9kg00qf 1502 3 primary primary JJ cord-022526-j9kg00qf 1502 4 cecal cecal JJ cord-022526-j9kg00qf 1502 5 impaction impaction NN cord-022526-j9kg00qf 1502 6 or or CC cord-022526-j9kg00qf 1502 7 impaction impaction NN cord-022526-j9kg00qf 1502 8 caused cause VBN cord-022526-j9kg00qf 1502 9 by by IN cord-022526-j9kg00qf 1502 10 an an DT cord-022526-j9kg00qf 1502 11 emptying empty VBG cord-022526-j9kg00qf 1502 12 defect defect NN cord-022526-j9kg00qf 1502 13 frequently frequently RB cord-022526-j9kg00qf 1502 14 require require VBP cord-022526-j9kg00qf 1502 15 surgery surgery NN cord-022526-j9kg00qf 1502 16 to to TO cord-022526-j9kg00qf 1502 17 prevent prevent VB cord-022526-j9kg00qf 1502 18 fatal fatal JJ cord-022526-j9kg00qf 1502 19 rupture rupture NN cord-022526-j9kg00qf 1502 20 . . . cord-022526-j9kg00qf 1503 1 The the DT cord-022526-j9kg00qf 1503 2 surgical surgical JJ cord-022526-j9kg00qf 1503 3 management management NN cord-022526-j9kg00qf 1503 4 of of IN cord-022526-j9kg00qf 1503 5 these these DT cord-022526-j9kg00qf 1503 6 cases case NNS cord-022526-j9kg00qf 1503 7 is be VBZ cord-022526-j9kg00qf 1503 8 controversial controversial JJ cord-022526-j9kg00qf 1503 9 and and CC cord-022526-j9kg00qf 1503 10 may may MD cord-022526-j9kg00qf 1503 11 include include VB cord-022526-j9kg00qf 1503 12 typhlotomy typhlotomy NN cord-022526-j9kg00qf 1503 13 alone alone RB cord-022526-j9kg00qf 1503 14 , , , cord-022526-j9kg00qf 1503 15 typhlotomy typhlotomy NN cord-022526-j9kg00qf 1503 16 with with IN cord-022526-j9kg00qf 1503 17 a a DT cord-022526-j9kg00qf 1503 18 bypass bypass NN cord-022526-j9kg00qf 1503 19 procedure procedure NN cord-022526-j9kg00qf 1503 20 such such JJ cord-022526-j9kg00qf 1503 21 as as IN cord-022526-j9kg00qf 1503 22 ileocolic ileocolic NNP cord-022526-j9kg00qf 1503 23 or or CC cord-022526-j9kg00qf 1503 24 jejunocolic jejunocolic JJ cord-022526-j9kg00qf 1503 25 anastomosis anastomosis NN cord-022526-j9kg00qf 1503 26 , , , cord-022526-j9kg00qf 1503 27 or or CC cord-022526-j9kg00qf 1503 28 a a DT cord-022526-j9kg00qf 1503 29 bypass bypass NN cord-022526-j9kg00qf 1503 30 without without IN cord-022526-j9kg00qf 1503 31 typhlotomy typhlotomy NN cord-022526-j9kg00qf 1503 32 . . . cord-022526-j9kg00qf 1504 1 41 41 CD cord-022526-j9kg00qf 1504 2 Most Most JJS cord-022526-j9kg00qf 1504 3 horses horse NNS cord-022526-j9kg00qf 1504 4 that that WDT cord-022526-j9kg00qf 1504 5 undergo undergo VBP cord-022526-j9kg00qf 1504 6 simple simple JJ cord-022526-j9kg00qf 1504 7 typhlotomy typhlotomy NN cord-022526-j9kg00qf 1504 8 have have VB cord-022526-j9kg00qf 1504 9 an an DT cord-022526-j9kg00qf 1504 10 uneventful uneventful JJ cord-022526-j9kg00qf 1504 11 recovery recovery NN cord-022526-j9kg00qf 1504 12 , , , cord-022526-j9kg00qf 1504 13 42 42 CD cord-022526-j9kg00qf 1504 14 although although IN cord-022526-j9kg00qf 1504 15 a a DT cord-022526-j9kg00qf 1504 16 small small JJ cord-022526-j9kg00qf 1504 17 number number NN cord-022526-j9kg00qf 1504 18 experience experience NN cord-022526-j9kg00qf 1504 19 impaction impaction NN cord-022526-j9kg00qf 1504 20 again again RB cord-022526-j9kg00qf 1504 21 and and CC cord-022526-j9kg00qf 1504 22 require require VB cord-022526-j9kg00qf 1504 23 a a DT cord-022526-j9kg00qf 1504 24 second second JJ cord-022526-j9kg00qf 1504 25 laparotomy laparotomy NN cord-022526-j9kg00qf 1504 26 . . . cord-022526-j9kg00qf 1505 1 Experimental experimental JJ cord-022526-j9kg00qf 1505 2 and and CC cord-022526-j9kg00qf 1505 3 anecdotal anecdotal JJ cord-022526-j9kg00qf 1505 4 evidence evidence NN cord-022526-j9kg00qf 1505 5 provides provide VBZ cord-022526-j9kg00qf 1505 6 a a DT cord-022526-j9kg00qf 1505 7 strong strong JJ cord-022526-j9kg00qf 1505 8 rationale rationale NN cord-022526-j9kg00qf 1505 9 for for IN cord-022526-j9kg00qf 1505 10 using use VBG cord-022526-j9kg00qf 1505 11 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1505 12 drugs drug NNS cord-022526-j9kg00qf 1505 13 to to TO cord-022526-j9kg00qf 1505 14 prevent prevent VB cord-022526-j9kg00qf 1505 15 and and CC cord-022526-j9kg00qf 1505 16 treat treat VB cord-022526-j9kg00qf 1505 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1505 18 ileus ileus NN cord-022526-j9kg00qf 1505 19 , , , cord-022526-j9kg00qf 1505 20 particularly particularly RB cord-022526-j9kg00qf 1505 21 in in IN cord-022526-j9kg00qf 1505 22 animals animal NNS cord-022526-j9kg00qf 1505 23 that that WDT cord-022526-j9kg00qf 1505 24 may may MD cord-022526-j9kg00qf 1505 25 have have VB cord-022526-j9kg00qf 1505 26 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1505 27 . . . cord-022526-j9kg00qf 1506 1 43 43 CD cord-022526-j9kg00qf 1507 1 Flunixin Flunixin NNP cord-022526-j9kg00qf 1507 2 meglumine meglumine NN cord-022526-j9kg00qf 1507 3 is be VBZ cord-022526-j9kg00qf 1507 4 used use VBN cord-022526-j9kg00qf 1507 5 widely widely RB cord-022526-j9kg00qf 1507 6 in in IN cord-022526-j9kg00qf 1507 7 equine equine JJ cord-022526-j9kg00qf 1507 8 practice practice NN cord-022526-j9kg00qf 1507 9 as as IN cord-022526-j9kg00qf 1507 10 an an DT cord-022526-j9kg00qf 1507 11 analgesic analgesic JJ cord-022526-j9kg00qf 1507 12 and and CC cord-022526-j9kg00qf 1507 13 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1507 14 agent agent NN cord-022526-j9kg00qf 1507 15 , , , cord-022526-j9kg00qf 1507 16 and and CC cord-022526-j9kg00qf 1507 17 it -PRON- PRP cord-022526-j9kg00qf 1507 18 ameliorates ameliorate VBZ cord-022526-j9kg00qf 1507 19 many many JJ cord-022526-j9kg00qf 1507 20 of of IN cord-022526-j9kg00qf 1507 21 the the DT cord-022526-j9kg00qf 1507 22 adverse adverse JJ cord-022526-j9kg00qf 1507 23 systemic systemic JJ cord-022526-j9kg00qf 1507 24 effects effect NNS cord-022526-j9kg00qf 1507 25 of of IN cord-022526-j9kg00qf 1507 26 endotoxin endotoxin NN cord-022526-j9kg00qf 1507 27 , , , cord-022526-j9kg00qf 1507 28 particularly particularly RB cord-022526-j9kg00qf 1507 29 those those DT cord-022526-j9kg00qf 1507 30 on on IN cord-022526-j9kg00qf 1507 31 the the DT cord-022526-j9kg00qf 1507 32 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 1507 33 system system NN cord-022526-j9kg00qf 1507 34 . . . cord-022526-j9kg00qf 1508 1 A a DT cord-022526-j9kg00qf 1508 2 potential potential JJ cord-022526-j9kg00qf 1508 3 negative negative JJ cord-022526-j9kg00qf 1508 4 effect effect NN cord-022526-j9kg00qf 1508 5 of of IN cord-022526-j9kg00qf 1508 6 NSAIDs nsaid NNS cord-022526-j9kg00qf 1508 7 on on IN cord-022526-j9kg00qf 1508 8 large large JJ cord-022526-j9kg00qf 1508 9 intestinal intestinal JJ cord-022526-j9kg00qf 1508 10 contractility contractility NN cord-022526-j9kg00qf 1508 11 has have VBZ cord-022526-j9kg00qf 1508 12 been be VBN cord-022526-j9kg00qf 1508 13 suggested suggest VBN cord-022526-j9kg00qf 1508 14 . . . cord-022526-j9kg00qf 1509 1 Broad broad JJ cord-022526-j9kg00qf 1509 2 - - HYPH cord-022526-j9kg00qf 1509 3 spectrum spectrum NN cord-022526-j9kg00qf 1509 4 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1509 5 are be VBP cord-022526-j9kg00qf 1509 6 indicated indicate VBN cord-022526-j9kg00qf 1509 7 when when WRB cord-022526-j9kg00qf 1509 8 one one CD cord-022526-j9kg00qf 1509 9 suspects suspect NNS cord-022526-j9kg00qf 1509 10 sepsis sepsis NN cord-022526-j9kg00qf 1509 11 or or CC cord-022526-j9kg00qf 1509 12 for for IN cord-022526-j9kg00qf 1509 13 the the DT cord-022526-j9kg00qf 1509 14 compromised compromised JJ cord-022526-j9kg00qf 1509 15 immune immune JJ cord-022526-j9kg00qf 1509 16 system system NN cord-022526-j9kg00qf 1509 17 , , , cord-022526-j9kg00qf 1509 18 as as IN cord-022526-j9kg00qf 1509 19 in in IN cord-022526-j9kg00qf 1509 20 cases case NNS cord-022526-j9kg00qf 1509 21 of of IN cord-022526-j9kg00qf 1509 22 moderate moderate JJ cord-022526-j9kg00qf 1509 23 to to IN cord-022526-j9kg00qf 1509 24 severe severe JJ cord-022526-j9kg00qf 1509 25 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1509 26 . . . cord-022526-j9kg00qf 1510 1 Theoretical theoretical JJ cord-022526-j9kg00qf 1510 2 concerns concern NNS cord-022526-j9kg00qf 1510 3 have have VBP cord-022526-j9kg00qf 1510 4 been be VBN cord-022526-j9kg00qf 1510 5 raised raise VBN cord-022526-j9kg00qf 1510 6 regarding regard VBG cord-022526-j9kg00qf 1510 7 the the DT cord-022526-j9kg00qf 1510 8 use use NN cord-022526-j9kg00qf 1510 9 of of IN cord-022526-j9kg00qf 1510 10 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 1510 11 antibiotics antibiotic NNS cord-022526-j9kg00qf 1510 12 in in IN cord-022526-j9kg00qf 1510 13 animals animal NNS cord-022526-j9kg00qf 1510 14 with with IN cord-022526-j9kg00qf 1510 15 ileus ileus NNP cord-022526-j9kg00qf 1510 16 . . . cord-022526-j9kg00qf 1511 1 High high JJ cord-022526-j9kg00qf 1511 2 concentrations concentration NNS cord-022526-j9kg00qf 1511 3 of of IN cord-022526-j9kg00qf 1511 4 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 1511 5 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1511 6 inhibited inhibit VBD cord-022526-j9kg00qf 1511 7 intestinal intestinal JJ cord-022526-j9kg00qf 1511 8 contractions contraction NNS cord-022526-j9kg00qf 1511 9 in in IN cord-022526-j9kg00qf 1511 10 exposed expose VBN cord-022526-j9kg00qf 1511 11 sections section NNS cord-022526-j9kg00qf 1511 12 of of IN cord-022526-j9kg00qf 1511 13 intestine intestine NN cord-022526-j9kg00qf 1511 14 in in IN cord-022526-j9kg00qf 1511 15 vitro vitro FW cord-022526-j9kg00qf 1511 16 , , , cord-022526-j9kg00qf 1511 17 but but CC cord-022526-j9kg00qf 1511 18 this this DT cord-022526-j9kg00qf 1511 19 inhibitory inhibitory JJ cord-022526-j9kg00qf 1511 20 effect effect NN cord-022526-j9kg00qf 1511 21 is be VBZ cord-022526-j9kg00qf 1511 22 unlikely unlikely JJ cord-022526-j9kg00qf 1511 23 to to TO cord-022526-j9kg00qf 1511 24 occur occur VB cord-022526-j9kg00qf 1511 25 at at IN cord-022526-j9kg00qf 1511 26 clinically clinically RB cord-022526-j9kg00qf 1511 27 relevant relevant JJ cord-022526-j9kg00qf 1511 28 doses dose NNS cord-022526-j9kg00qf 1511 29 . . . cord-022526-j9kg00qf 1512 1 44 44 CD cord-022526-j9kg00qf 1512 2 Motility motility NN cord-022526-j9kg00qf 1512 3 - - HYPH cord-022526-j9kg00qf 1512 4 enhancing enhance VBG cord-022526-j9kg00qf 1512 5 drugs drug NNS cord-022526-j9kg00qf 1512 6 have have VBP cord-022526-j9kg00qf 1512 7 been be VBN cord-022526-j9kg00qf 1512 8 advocated advocate VBN cord-022526-j9kg00qf 1512 9 to to TO cord-022526-j9kg00qf 1512 10 treat treat VB cord-022526-j9kg00qf 1512 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1512 12 ileus ileus NN cord-022526-j9kg00qf 1512 13 . . . cord-022526-j9kg00qf 1513 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 1513 2 , , , cord-022526-j9kg00qf 1513 3 information information NN cord-022526-j9kg00qf 1513 4 directly directly RB cord-022526-j9kg00qf 1513 5 pertinent pertinent JJ cord-022526-j9kg00qf 1513 6 to to IN cord-022526-j9kg00qf 1513 7 horses horse NNS cord-022526-j9kg00qf 1513 8 is be VBZ cord-022526-j9kg00qf 1513 9 limited limit VBN cord-022526-j9kg00qf 1513 10 and and CC cord-022526-j9kg00qf 1513 11 must must MD cord-022526-j9kg00qf 1513 12 be be VB cord-022526-j9kg00qf 1513 13 extrapolated extrapolate VBN cord-022526-j9kg00qf 1513 14 cautiously cautiously RB cord-022526-j9kg00qf 1513 15 from from IN cord-022526-j9kg00qf 1513 16 that that DT cord-022526-j9kg00qf 1513 17 of of IN cord-022526-j9kg00qf 1513 18 other other JJ cord-022526-j9kg00qf 1513 19 species specie NNS cord-022526-j9kg00qf 1513 20 because because IN cord-022526-j9kg00qf 1513 21 of of IN cord-022526-j9kg00qf 1513 22 the the DT cord-022526-j9kg00qf 1513 23 differences difference NNS cord-022526-j9kg00qf 1513 24 in in IN cord-022526-j9kg00qf 1513 25 intestinal intestinal JJ cord-022526-j9kg00qf 1513 26 anatomy anatomy NN cord-022526-j9kg00qf 1513 27 and and CC cord-022526-j9kg00qf 1513 28 physiology physiology NN cord-022526-j9kg00qf 1513 29 . . . cord-022526-j9kg00qf 1514 1 Prokinetic prokinetic JJ cord-022526-j9kg00qf 1514 2 drugs drug NNS cord-022526-j9kg00qf 1514 3 potentially potentially RB cord-022526-j9kg00qf 1514 4 can can MD cord-022526-j9kg00qf 1514 5 shorten shorten VB cord-022526-j9kg00qf 1514 6 the the DT cord-022526-j9kg00qf 1514 7 length length NN cord-022526-j9kg00qf 1514 8 of of IN cord-022526-j9kg00qf 1514 9 hospitalization hospitalization NN cord-022526-j9kg00qf 1514 10 , , , cord-022526-j9kg00qf 1514 11 thereby thereby RB cord-022526-j9kg00qf 1514 12 reducing reduce VBG cord-022526-j9kg00qf 1514 13 the the DT cord-022526-j9kg00qf 1514 14 cost cost NN cord-022526-j9kg00qf 1514 15 of of IN cord-022526-j9kg00qf 1514 16 treatment treatment NN cord-022526-j9kg00qf 1514 17 and and CC cord-022526-j9kg00qf 1514 18 the the DT cord-022526-j9kg00qf 1514 19 number number NN cord-022526-j9kg00qf 1514 20 of of IN cord-022526-j9kg00qf 1514 21 potential potential JJ cord-022526-j9kg00qf 1514 22 complications complication NNS cord-022526-j9kg00qf 1514 23 such such JJ cord-022526-j9kg00qf 1514 24 as as IN cord-022526-j9kg00qf 1514 25 weight weight NN cord-022526-j9kg00qf 1514 26 loss loss NN cord-022526-j9kg00qf 1514 27 , , , cord-022526-j9kg00qf 1514 28 thrombophlebitis thrombophlebitis NNP cord-022526-j9kg00qf 1514 29 , , , cord-022526-j9kg00qf 1514 30 and and CC cord-022526-j9kg00qf 1514 31 laminitis laminitis NN cord-022526-j9kg00qf 1514 32 . . . cord-022526-j9kg00qf 1515 1 Experimental experimental JJ cord-022526-j9kg00qf 1515 2 evidence evidence NN cord-022526-j9kg00qf 1515 3 indicates indicate VBZ cord-022526-j9kg00qf 1515 4 that that IN cord-022526-j9kg00qf 1515 5 prokinetic prokinetic JJ cord-022526-j9kg00qf 1515 6 drugs drug NNS cord-022526-j9kg00qf 1515 7 can can MD cord-022526-j9kg00qf 1515 8 minimize minimize VB cord-022526-j9kg00qf 1515 9 the the DT cord-022526-j9kg00qf 1515 10 development development NN cord-022526-j9kg00qf 1515 11 of of IN cord-022526-j9kg00qf 1515 12 postoperative postoperative JJ cord-022526-j9kg00qf 1515 13 abdominal abdominal JJ cord-022526-j9kg00qf 1515 14 adhesions adhesion NNS cord-022526-j9kg00qf 1515 15 . . . cord-022526-j9kg00qf 1516 1 45 45 CD cord-022526-j9kg00qf 1516 2 Most Most JJS cord-022526-j9kg00qf 1516 3 prokinetic prokinetic JJ cord-022526-j9kg00qf 1516 4 drugs drug NNS cord-022526-j9kg00qf 1516 5 require require VBP cord-022526-j9kg00qf 1516 6 a a DT cord-022526-j9kg00qf 1516 7 healthy healthy JJ cord-022526-j9kg00qf 1516 8 gut gut NN cord-022526-j9kg00qf 1516 9 wall wall NN cord-022526-j9kg00qf 1516 10 to to TO cord-022526-j9kg00qf 1516 11 enhance enhance VB cord-022526-j9kg00qf 1516 12 intestinal intestinal JJ cord-022526-j9kg00qf 1516 13 contraction contraction NN cord-022526-j9kg00qf 1516 14 . . . cord-022526-j9kg00qf 1517 1 Therefore therefore RB cord-022526-j9kg00qf 1517 2 one one PRP cord-022526-j9kg00qf 1517 3 should should MD cord-022526-j9kg00qf 1517 4 not not RB cord-022526-j9kg00qf 1517 5 assume assume VB cord-022526-j9kg00qf 1517 6 that that IN cord-022526-j9kg00qf 1517 7 many many JJ cord-022526-j9kg00qf 1517 8 of of IN cord-022526-j9kg00qf 1517 9 these these DT cord-022526-j9kg00qf 1517 10 drugs drug NNS cord-022526-j9kg00qf 1517 11 would would MD cord-022526-j9kg00qf 1517 12 be be VB cord-022526-j9kg00qf 1517 13 effective effective JJ cord-022526-j9kg00qf 1517 14 in in IN cord-022526-j9kg00qf 1517 15 the the DT cord-022526-j9kg00qf 1517 16 presence presence NN cord-022526-j9kg00qf 1517 17 of of IN cord-022526-j9kg00qf 1517 18 an an DT cord-022526-j9kg00qf 1517 19 inflammatory inflammatory JJ cord-022526-j9kg00qf 1517 20 injury injury NN cord-022526-j9kg00qf 1517 21 such such JJ cord-022526-j9kg00qf 1517 22 as as IN cord-022526-j9kg00qf 1517 23 that that DT cord-022526-j9kg00qf 1517 24 which which WDT cord-022526-j9kg00qf 1517 25 can can MD cord-022526-j9kg00qf 1517 26 occur occur VB cord-022526-j9kg00qf 1517 27 after after IN cord-022526-j9kg00qf 1517 28 intestinal intestinal JJ cord-022526-j9kg00qf 1517 29 manipulation manipulation NN cord-022526-j9kg00qf 1517 30 at at IN cord-022526-j9kg00qf 1517 31 surgery surgery NN cord-022526-j9kg00qf 1517 32 or or CC cord-022526-j9kg00qf 1517 33 that that IN cord-022526-j9kg00qf 1517 34 associated associate VBN cord-022526-j9kg00qf 1517 35 with with IN cord-022526-j9kg00qf 1517 36 duodenitis duodenitis NN cord-022526-j9kg00qf 1517 37 - - HYPH cord-022526-j9kg00qf 1517 38 proximal proximal JJ cord-022526-j9kg00qf 1517 39 jejunitis jejunitis NN cord-022526-j9kg00qf 1517 40 . . . cord-022526-j9kg00qf 1518 1 Bethanechol Bethanechol NNP cord-022526-j9kg00qf 1518 2 is be VBZ cord-022526-j9kg00qf 1518 3 a a DT cord-022526-j9kg00qf 1518 4 parasympathomimetic parasympathomimetic JJ cord-022526-j9kg00qf 1518 5 agent agent NN cord-022526-j9kg00qf 1518 6 that that WDT cord-022526-j9kg00qf 1518 7 acts act VBZ cord-022526-j9kg00qf 1518 8 at at IN cord-022526-j9kg00qf 1518 9 the the DT cord-022526-j9kg00qf 1518 10 level level NN cord-022526-j9kg00qf 1518 11 of of IN cord-022526-j9kg00qf 1518 12 the the DT cord-022526-j9kg00qf 1518 13 myenteric myenteric JJ cord-022526-j9kg00qf 1518 14 plexus plexus NN cord-022526-j9kg00qf 1518 15 and and CC cord-022526-j9kg00qf 1518 16 directly directly RB cord-022526-j9kg00qf 1518 17 on on IN cord-022526-j9kg00qf 1518 18 intestinal intestinal JJ cord-022526-j9kg00qf 1518 19 smooth smooth JJ cord-022526-j9kg00qf 1518 20 cells cell NNS cord-022526-j9kg00qf 1518 21 through through IN cord-022526-j9kg00qf 1518 22 muscarinic muscarinic JJ cord-022526-j9kg00qf 1518 23 receptors receptor NNS cord-022526-j9kg00qf 1518 24 . . . cord-022526-j9kg00qf 1519 1 Bethanechol Bethanechol NNP cord-022526-j9kg00qf 1519 2 is be VBZ cord-022526-j9kg00qf 1519 3 a a DT cord-022526-j9kg00qf 1519 4 synthetic synthetic JJ cord-022526-j9kg00qf 1519 5 ester ester NN cord-022526-j9kg00qf 1519 6 of of IN cord-022526-j9kg00qf 1519 7 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1519 8 and and CC cord-022526-j9kg00qf 1519 9 is be VBZ cord-022526-j9kg00qf 1519 10 not not RB cord-022526-j9kg00qf 1519 11 degraded degrade VBN cord-022526-j9kg00qf 1519 12 by by IN cord-022526-j9kg00qf 1519 13 anticholinesterase anticholinesterase NN cord-022526-j9kg00qf 1519 14 . . . cord-022526-j9kg00qf 1520 1 Bethanechol Bethanechol NNP cord-022526-j9kg00qf 1520 2 has have VBZ cord-022526-j9kg00qf 1520 3 cholinergic cholinergic JJ cord-022526-j9kg00qf 1520 4 side side NN cord-022526-j9kg00qf 1520 5 effects effect NNS cord-022526-j9kg00qf 1520 6 , , , cord-022526-j9kg00qf 1520 7 including include VBG cord-022526-j9kg00qf 1520 8 abdominal abdominal JJ cord-022526-j9kg00qf 1520 9 discomfort discomfort NN cord-022526-j9kg00qf 1520 10 , , , cord-022526-j9kg00qf 1520 11 sweating sweating NN cord-022526-j9kg00qf 1520 12 , , , cord-022526-j9kg00qf 1520 13 and and CC cord-022526-j9kg00qf 1520 14 salivation salivation NN cord-022526-j9kg00qf 1520 15 , , , cord-022526-j9kg00qf 1520 16 although although IN cord-022526-j9kg00qf 1520 17 these these DT cord-022526-j9kg00qf 1520 18 are be VBP cord-022526-j9kg00qf 1520 19 minimal minimal JJ cord-022526-j9kg00qf 1520 20 when when WRB cord-022526-j9kg00qf 1520 21 the the DT cord-022526-j9kg00qf 1520 22 drug drug NN cord-022526-j9kg00qf 1520 23 is be VBZ cord-022526-j9kg00qf 1520 24 administered administer VBN cord-022526-j9kg00qf 1520 25 at at IN cord-022526-j9kg00qf 1520 26 0.025 0.025 CD cord-022526-j9kg00qf 1520 27 mg mg NNP cord-022526-j9kg00qf 1520 28 / / SYM cord-022526-j9kg00qf 1520 29 kg kg NNP cord-022526-j9kg00qf 1520 30 body body NN cord-022526-j9kg00qf 1520 31 mass mass NN cord-022526-j9kg00qf 1520 32 subcutaneously subcutaneously RB cord-022526-j9kg00qf 1520 33 or or CC cord-022526-j9kg00qf 1520 34 orally orally RB cord-022526-j9kg00qf 1520 35 . . . cord-022526-j9kg00qf 1521 1 Bethanechol Bethanechol NNP cord-022526-j9kg00qf 1521 2 has have VBZ cord-022526-j9kg00qf 1521 3 efficacy efficacy NN cord-022526-j9kg00qf 1521 4 in in IN cord-022526-j9kg00qf 1521 5 diseases disease NNS cord-022526-j9kg00qf 1521 6 that that WDT cord-022526-j9kg00qf 1521 7 involve involve VBP cord-022526-j9kg00qf 1521 8 abnormal abnormal JJ cord-022526-j9kg00qf 1521 9 gastric gastric JJ cord-022526-j9kg00qf 1521 10 emptying emptying NN cord-022526-j9kg00qf 1521 11 and and CC cord-022526-j9kg00qf 1521 12 delayed delay VBN cord-022526-j9kg00qf 1521 13 small small JJ cord-022526-j9kg00qf 1521 14 intestinal intestinal JJ cord-022526-j9kg00qf 1521 15 transit transit NN cord-022526-j9kg00qf 1521 16 and and CC cord-022526-j9kg00qf 1521 17 has have VBZ cord-022526-j9kg00qf 1521 18 been be VBN cord-022526-j9kg00qf 1521 19 shown show VBN cord-022526-j9kg00qf 1521 20 to to TO cord-022526-j9kg00qf 1521 21 increase increase VB cord-022526-j9kg00qf 1521 22 gastric gastric JJ cord-022526-j9kg00qf 1521 23 contractility contractility NN cord-022526-j9kg00qf 1521 24 and and CC cord-022526-j9kg00qf 1521 25 hasten hasten VB cord-022526-j9kg00qf 1521 26 the the DT cord-022526-j9kg00qf 1521 27 emptying emptying NN cord-022526-j9kg00qf 1521 28 of of IN cord-022526-j9kg00qf 1521 29 liquid liquid JJ cord-022526-j9kg00qf 1521 30 and and CC cord-022526-j9kg00qf 1521 31 solid solid JJ cord-022526-j9kg00qf 1521 32 phase phase NN cord-022526-j9kg00qf 1521 33 markers marker NNS cord-022526-j9kg00qf 1521 34 from from IN cord-022526-j9kg00qf 1521 35 the the DT cord-022526-j9kg00qf 1521 36 stomach stomach NN cord-022526-j9kg00qf 1521 37 of of IN cord-022526-j9kg00qf 1521 38 normal normal JJ cord-022526-j9kg00qf 1521 39 horses horse NNS cord-022526-j9kg00qf 1521 40 . . . cord-022526-j9kg00qf 1522 1 [ [ -LRB- cord-022526-j9kg00qf 1522 2 46 46 CD cord-022526-j9kg00qf 1522 3 ] ] -RRB- cord-022526-j9kg00qf 1522 4 [ [ -LRB- cord-022526-j9kg00qf 1522 5 47 47 CD cord-022526-j9kg00qf 1522 6 ] ] -RRB- cord-022526-j9kg00qf 1523 1 Bethanechol Bethanechol NNP cord-022526-j9kg00qf 1523 2 also also RB cord-022526-j9kg00qf 1523 3 increases increase VBZ cord-022526-j9kg00qf 1523 4 the the DT cord-022526-j9kg00qf 1523 5 strength strength NN cord-022526-j9kg00qf 1523 6 and and CC cord-022526-j9kg00qf 1523 7 duration duration NN cord-022526-j9kg00qf 1523 8 of of IN cord-022526-j9kg00qf 1523 9 wall wall NN cord-022526-j9kg00qf 1523 10 contractions contraction NNS cord-022526-j9kg00qf 1523 11 in in IN cord-022526-j9kg00qf 1523 12 the the DT cord-022526-j9kg00qf 1523 13 cecum cecum NN cord-022526-j9kg00qf 1523 14 and and CC cord-022526-j9kg00qf 1523 15 right right JJ cord-022526-j9kg00qf 1523 16 ventral ventral JJ cord-022526-j9kg00qf 1523 17 colon colon NN cord-022526-j9kg00qf 1523 18 and and CC cord-022526-j9kg00qf 1523 19 consequently consequently RB cord-022526-j9kg00qf 1523 20 speeds speed VBZ cord-022526-j9kg00qf 1523 21 up up RP cord-022526-j9kg00qf 1523 22 cecal cecal JJ cord-022526-j9kg00qf 1523 23 emptying emptying NN cord-022526-j9kg00qf 1523 24 . . . cord-022526-j9kg00qf 1524 1 Neostigmine Neostigmine NNP cord-022526-j9kg00qf 1524 2 increases increase VBZ cord-022526-j9kg00qf 1524 3 receptor receptor NN cord-022526-j9kg00qf 1524 4 levels level NNS cord-022526-j9kg00qf 1524 5 of of IN cord-022526-j9kg00qf 1524 6 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1524 7 by by IN cord-022526-j9kg00qf 1524 8 inhibiting inhibit VBG cord-022526-j9kg00qf 1524 9 cholinesterase cholinesterase NN cord-022526-j9kg00qf 1524 10 . . . cord-022526-j9kg00qf 1525 1 The the DT cord-022526-j9kg00qf 1525 2 drug drug NN cord-022526-j9kg00qf 1525 3 ( ( -LRB- cord-022526-j9kg00qf 1525 4 0.022 0.022 CD cord-022526-j9kg00qf 1525 5 to to IN cord-022526-j9kg00qf 1525 6 0.025 0.025 CD cord-022526-j9kg00qf 1525 7 mg mg NN cord-022526-j9kg00qf 1525 8 / / SYM cord-022526-j9kg00qf 1525 9 kg kg NNP cord-022526-j9kg00qf 1525 10 intravenously intravenously RB cord-022526-j9kg00qf 1525 11 ) ) -RRB- cord-022526-j9kg00qf 1525 12 promotes promote VBZ cord-022526-j9kg00qf 1525 13 cecal cecal JJ cord-022526-j9kg00qf 1525 14 and and CC cord-022526-j9kg00qf 1525 15 colonic colonic JJ cord-022526-j9kg00qf 1525 16 contractile contractile JJ cord-022526-j9kg00qf 1525 17 activity activity NN cord-022526-j9kg00qf 1525 18 and and CC cord-022526-j9kg00qf 1525 19 hastens hasten VBZ cord-022526-j9kg00qf 1525 20 the the DT cord-022526-j9kg00qf 1525 21 emptying emptying NN cord-022526-j9kg00qf 1525 22 of of IN cord-022526-j9kg00qf 1525 23 radiolabeled radiolabeled JJ cord-022526-j9kg00qf 1525 24 markers marker NNS cord-022526-j9kg00qf 1525 25 from from IN cord-022526-j9kg00qf 1525 26 the the DT cord-022526-j9kg00qf 1525 27 cecum cecum NN cord-022526-j9kg00qf 1525 28 . . . cord-022526-j9kg00qf 1526 1 24 24 CD cord-022526-j9kg00qf 1526 2 Neostigmine Neostigmine NNP cord-022526-j9kg00qf 1526 3 has have VBZ cord-022526-j9kg00qf 1526 4 been be VBN cord-022526-j9kg00qf 1526 5 used use VBN cord-022526-j9kg00qf 1526 6 to to TO cord-022526-j9kg00qf 1526 7 manage manage VB cord-022526-j9kg00qf 1526 8 small small JJ cord-022526-j9kg00qf 1526 9 intestinal intestinal JJ cord-022526-j9kg00qf 1526 10 ileus ileus NN cord-022526-j9kg00qf 1526 11 , , , cord-022526-j9kg00qf 1526 12 but but CC cord-022526-j9kg00qf 1526 13 it -PRON- PRP cord-022526-j9kg00qf 1526 14 significantly significantly RB cord-022526-j9kg00qf 1526 15 delayed delay VBD cord-022526-j9kg00qf 1526 16 the the DT cord-022526-j9kg00qf 1526 17 emptying emptying NN cord-022526-j9kg00qf 1526 18 of of IN cord-022526-j9kg00qf 1526 19 6-mm 6-mm CD cord-022526-j9kg00qf 1526 20 beads bead NNS cord-022526-j9kg00qf 1526 21 from from IN cord-022526-j9kg00qf 1526 22 the the DT cord-022526-j9kg00qf 1526 23 stomach stomach NN cord-022526-j9kg00qf 1526 24 of of IN cord-022526-j9kg00qf 1526 25 normal normal JJ cord-022526-j9kg00qf 1526 26 adult adult NN cord-022526-j9kg00qf 1526 27 horses horse NNS cord-022526-j9kg00qf 1526 28 . . . cord-022526-j9kg00qf 1527 1 48 48 CD cord-022526-j9kg00qf 1527 2 Metoclopramide Metoclopramide NNP cord-022526-j9kg00qf 1527 3 acts act VBZ cord-022526-j9kg00qf 1527 4 principally principally RB cord-022526-j9kg00qf 1527 5 as as IN cord-022526-j9kg00qf 1527 6 a a DT cord-022526-j9kg00qf 1527 7 5-hydroxytryptamine 5-hydroxytryptamine CD cord-022526-j9kg00qf 1527 8 4-receptor 4-receptor CD cord-022526-j9kg00qf 1527 9 ( ( -LRB- cord-022526-j9kg00qf 1527 10 5HT-4 5ht-4 CD cord-022526-j9kg00qf 1527 11 ) ) -RRB- cord-022526-j9kg00qf 1527 12 agonist agonist NN cord-022526-j9kg00qf 1527 13 and and CC cord-022526-j9kg00qf 1527 14 5HT-3-receptor 5ht-3-receptor CD cord-022526-j9kg00qf 1527 15 antagonist antagonist NN cord-022526-j9kg00qf 1527 16 . . . cord-022526-j9kg00qf 1528 1 In in IN cord-022526-j9kg00qf 1528 2 contrast contrast NN cord-022526-j9kg00qf 1528 3 to to IN cord-022526-j9kg00qf 1528 4 newer new JJR cord-022526-j9kg00qf 1528 5 generation generation NN cord-022526-j9kg00qf 1528 6 benzamides benzamide NNS cord-022526-j9kg00qf 1528 7 , , , cord-022526-j9kg00qf 1528 8 metoclopramide metoclopramide NN cord-022526-j9kg00qf 1528 9 is be VBZ cord-022526-j9kg00qf 1528 10 also also RB cord-022526-j9kg00qf 1528 11 an an DT cord-022526-j9kg00qf 1528 12 antagonist antagonist NN cord-022526-j9kg00qf 1528 13 at at IN cord-022526-j9kg00qf 1528 14 dopamine dopamine NN cord-022526-j9kg00qf 1528 15 1 1 CD cord-022526-j9kg00qf 1528 16 ( ( -LRB- cord-022526-j9kg00qf 1528 17 DA DA NNP cord-022526-j9kg00qf 1528 18 1 1 CD cord-022526-j9kg00qf 1528 19 ) ) -RRB- cord-022526-j9kg00qf 1528 20 and and CC cord-022526-j9kg00qf 1528 21 2 2 LS cord-022526-j9kg00qf 1528 22 ( ( -LRB- cord-022526-j9kg00qf 1528 23 DA DA NNP cord-022526-j9kg00qf 1528 24 2 2 CD cord-022526-j9kg00qf 1528 25 ) ) -RRB- cord-022526-j9kg00qf 1528 26 receptors receptor NNS cord-022526-j9kg00qf 1528 27 . . . cord-022526-j9kg00qf 1529 1 Antagonism antagonism NN cord-022526-j9kg00qf 1529 2 of of IN cord-022526-j9kg00qf 1529 3 prejunctional prejunctional NNP cord-022526-j9kg00qf 1529 4 DA DA NNP cord-022526-j9kg00qf 1529 5 2 2 CD cord-022526-j9kg00qf 1529 6 receptors receptor NNS cord-022526-j9kg00qf 1529 7 facilitates facilitate VBZ cord-022526-j9kg00qf 1529 8 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1529 9 release release NN cord-022526-j9kg00qf 1529 10 and and CC cord-022526-j9kg00qf 1529 11 smooth smooth JJ cord-022526-j9kg00qf 1529 12 muscle muscle NN cord-022526-j9kg00qf 1529 13 contraction contraction NN cord-022526-j9kg00qf 1529 14 . . . cord-022526-j9kg00qf 1530 1 Metoclopramide Metoclopramide NNP cord-022526-j9kg00qf 1530 2 crosses cross VBZ cord-022526-j9kg00qf 1530 3 the the DT cord-022526-j9kg00qf 1530 4 blood blood NN cord-022526-j9kg00qf 1530 5 - - HYPH cord-022526-j9kg00qf 1530 6 brain brain NN cord-022526-j9kg00qf 1530 7 barrier barrier NN cord-022526-j9kg00qf 1530 8 , , , cord-022526-j9kg00qf 1530 9 where where WRB cord-022526-j9kg00qf 1530 10 its -PRON- PRP$ cord-022526-j9kg00qf 1530 11 antagonist antagonist NN cord-022526-j9kg00qf 1530 12 properties property NNS cord-022526-j9kg00qf 1530 13 on on IN cord-022526-j9kg00qf 1530 14 central central JJ cord-022526-j9kg00qf 1530 15 DA DA NNP cord-022526-j9kg00qf 1530 16 2 2 CD cord-022526-j9kg00qf 1530 17 receptors receptor NNS cord-022526-j9kg00qf 1530 18 can can MD cord-022526-j9kg00qf 1530 19 result result VB cord-022526-j9kg00qf 1530 20 in in IN cord-022526-j9kg00qf 1530 21 extrapyramidal extrapyramidal JJ cord-022526-j9kg00qf 1530 22 signs sign NNS cord-022526-j9kg00qf 1530 23 , , , cord-022526-j9kg00qf 1530 24 including include VBG cord-022526-j9kg00qf 1530 25 seizure seizure NN cord-022526-j9kg00qf 1530 26 . . . cord-022526-j9kg00qf 1531 1 These these DT cord-022526-j9kg00qf 1531 2 signs sign NNS cord-022526-j9kg00qf 1531 3 were be VBD cord-022526-j9kg00qf 1531 4 responsible responsible JJ cord-022526-j9kg00qf 1531 5 for for IN cord-022526-j9kg00qf 1531 6 poor poor JJ cord-022526-j9kg00qf 1531 7 acceptance acceptance NN cord-022526-j9kg00qf 1531 8 of of IN cord-022526-j9kg00qf 1531 9 the the DT cord-022526-j9kg00qf 1531 10 drug drug NN cord-022526-j9kg00qf 1531 11 in in IN cord-022526-j9kg00qf 1531 12 equine equine JJ cord-022526-j9kg00qf 1531 13 practice practice NN cord-022526-j9kg00qf 1531 14 . . . cord-022526-j9kg00qf 1532 1 Most Most JJS cord-022526-j9kg00qf 1532 2 investigators investigator NNS cord-022526-j9kg00qf 1532 3 have have VBP cord-022526-j9kg00qf 1532 4 failed fail VBN cord-022526-j9kg00qf 1532 5 to to TO cord-022526-j9kg00qf 1532 6 demonstrate demonstrate VB cord-022526-j9kg00qf 1532 7 significant significant JJ cord-022526-j9kg00qf 1532 8 effects effect NNS cord-022526-j9kg00qf 1532 9 of of IN cord-022526-j9kg00qf 1532 10 metoclopramide metoclopramide NN cord-022526-j9kg00qf 1532 11 in in IN cord-022526-j9kg00qf 1532 12 experimental experimental JJ cord-022526-j9kg00qf 1532 13 animals animal NNS cord-022526-j9kg00qf 1532 14 , , , cord-022526-j9kg00qf 1532 15 but but CC cord-022526-j9kg00qf 1532 16 constant constant JJ cord-022526-j9kg00qf 1532 17 intravenous intravenous JJ cord-022526-j9kg00qf 1532 18 infusion infusion NN cord-022526-j9kg00qf 1532 19 ( ( -LRB- cord-022526-j9kg00qf 1532 20 0.04 0.04 CD cord-022526-j9kg00qf 1532 21 mg mg NNP cord-022526-j9kg00qf 1532 22 / / SYM cord-022526-j9kg00qf 1532 23 kg kg NNP cord-022526-j9kg00qf 1532 24 / / SYM cord-022526-j9kg00qf 1532 25 hr hr NN cord-022526-j9kg00qf 1532 26 ) ) -RRB- cord-022526-j9kg00qf 1532 27 in in IN cord-022526-j9kg00qf 1532 28 a a DT cord-022526-j9kg00qf 1532 29 population population NN cord-022526-j9kg00qf 1532 30 of of IN cord-022526-j9kg00qf 1532 31 postoperative postoperative JJ cord-022526-j9kg00qf 1532 32 horses horse NNS cord-022526-j9kg00qf 1532 33 significantly significantly RB cord-022526-j9kg00qf 1532 34 decreased decrease VBD cord-022526-j9kg00qf 1532 35 the the DT cord-022526-j9kg00qf 1532 36 volume volume NN cord-022526-j9kg00qf 1532 37 and and CC cord-022526-j9kg00qf 1532 38 duration duration NN cord-022526-j9kg00qf 1532 39 of of IN cord-022526-j9kg00qf 1532 40 gastric gastric JJ cord-022526-j9kg00qf 1532 41 reflux reflux NN cord-022526-j9kg00qf 1532 42 over over IN cord-022526-j9kg00qf 1532 43 control control NN cord-022526-j9kg00qf 1532 44 and and CC cord-022526-j9kg00qf 1532 45 intermittent intermittent JJ cord-022526-j9kg00qf 1532 46 drug drug NN cord-022526-j9kg00qf 1532 47 infusion infusion NN cord-022526-j9kg00qf 1532 48 groups group NNS cord-022526-j9kg00qf 1532 49 . . . cord-022526-j9kg00qf 1533 1 49 49 CD cord-022526-j9kg00qf 1533 2 Infusion infusion NN cord-022526-j9kg00qf 1533 3 was be VBD cord-022526-j9kg00qf 1533 4 well well RB cord-022526-j9kg00qf 1533 5 tolerated tolerate VBN cord-022526-j9kg00qf 1533 6 and and CC cord-022526-j9kg00qf 1533 7 appeared appear VBD cord-022526-j9kg00qf 1533 8 to to TO cord-022526-j9kg00qf 1533 9 be be VB cord-022526-j9kg00qf 1533 10 superior superior JJ cord-022526-j9kg00qf 1533 11 to to IN cord-022526-j9kg00qf 1533 12 intermittent intermittent JJ cord-022526-j9kg00qf 1533 13 infusion infusion NN cord-022526-j9kg00qf 1533 14 or or CC cord-022526-j9kg00qf 1533 15 no no DT cord-022526-j9kg00qf 1533 16 treatment treatment NN cord-022526-j9kg00qf 1533 17 at at RB cord-022526-j9kg00qf 1533 18 all all RB cord-022526-j9kg00qf 1533 19 . . . cord-022526-j9kg00qf 1534 1 Cisapride Cisapride NNP cord-022526-j9kg00qf 1534 2 is be VBZ cord-022526-j9kg00qf 1534 3 a a DT cord-022526-j9kg00qf 1534 4 second second JJ cord-022526-j9kg00qf 1534 5 - - HYPH cord-022526-j9kg00qf 1534 6 generation generation NN cord-022526-j9kg00qf 1534 7 benzamide benzamide NN cord-022526-j9kg00qf 1534 8 that that WDT cord-022526-j9kg00qf 1534 9 acts act VBZ cord-022526-j9kg00qf 1534 10 as as IN cord-022526-j9kg00qf 1534 11 a a DT cord-022526-j9kg00qf 1534 12 5HT-4 5ht-4 CD cord-022526-j9kg00qf 1534 13 agonist agonist NN cord-022526-j9kg00qf 1534 14 and and CC cord-022526-j9kg00qf 1534 15 5HT-3 5ht-3 CD cord-022526-j9kg00qf 1534 16 receptor receptor NN cord-022526-j9kg00qf 1534 17 antagonist antagonist NN cord-022526-j9kg00qf 1534 18 but but CC cord-022526-j9kg00qf 1534 19 is be VBZ cord-022526-j9kg00qf 1534 20 without without IN cord-022526-j9kg00qf 1534 21 antidopaminergic antidopaminergic NNP cord-022526-j9kg00qf 1534 22 action action NN cord-022526-j9kg00qf 1534 23 . . . cord-022526-j9kg00qf 1535 1 Stimulation stimulation NN cord-022526-j9kg00qf 1535 2 of of IN cord-022526-j9kg00qf 1535 3 5HT-4 5ht-4 CD cord-022526-j9kg00qf 1535 4 receptors receptor NNS cord-022526-j9kg00qf 1535 5 within within IN cord-022526-j9kg00qf 1535 6 the the DT cord-022526-j9kg00qf 1535 7 enteric enteric JJ cord-022526-j9kg00qf 1535 8 nervous nervous JJ cord-022526-j9kg00qf 1535 9 system system NN cord-022526-j9kg00qf 1535 10 enhances enhance VBZ cord-022526-j9kg00qf 1535 11 release release NN cord-022526-j9kg00qf 1535 12 of of IN cord-022526-j9kg00qf 1535 13 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1535 14 from from IN cord-022526-j9kg00qf 1535 15 the the DT cord-022526-j9kg00qf 1535 16 myenteric myenteric JJ cord-022526-j9kg00qf 1535 17 plexus plexus NN cord-022526-j9kg00qf 1535 18 . . . cord-022526-j9kg00qf 1536 1 Several several JJ cord-022526-j9kg00qf 1536 2 reports report NNS cord-022526-j9kg00qf 1536 3 suggest suggest VBP cord-022526-j9kg00qf 1536 4 the the DT cord-022526-j9kg00qf 1536 5 efficacy efficacy NN cord-022526-j9kg00qf 1536 6 of of IN cord-022526-j9kg00qf 1536 7 cisapride cisapride NN cord-022526-j9kg00qf 1536 8 in in IN cord-022526-j9kg00qf 1536 9 managing manage VBG cord-022526-j9kg00qf 1536 10 intestinal intestinal JJ cord-022526-j9kg00qf 1536 11 disease disease NN cord-022526-j9kg00qf 1536 12 in in IN cord-022526-j9kg00qf 1536 13 horses horse NNS cord-022526-j9kg00qf 1536 14 , , , cord-022526-j9kg00qf 1536 15 including include VBG cord-022526-j9kg00qf 1536 16 the the DT cord-022526-j9kg00qf 1536 17 resolution resolution NN cord-022526-j9kg00qf 1536 18 of of IN cord-022526-j9kg00qf 1536 19 persistent persistent JJ cord-022526-j9kg00qf 1536 20 large large JJ cord-022526-j9kg00qf 1536 21 colon colon NN cord-022526-j9kg00qf 1536 22 impaction impaction NN cord-022526-j9kg00qf 1536 23 , , , cord-022526-j9kg00qf 1536 24 treatment treatment NN cord-022526-j9kg00qf 1536 25 of of IN cord-022526-j9kg00qf 1536 26 equine equine JJ cord-022526-j9kg00qf 1536 27 grass grass NN cord-022526-j9kg00qf 1536 28 sickness sickness NN cord-022526-j9kg00qf 1536 29 , , , cord-022526-j9kg00qf 1536 30 and and CC cord-022526-j9kg00qf 1536 31 as as IN cord-022526-j9kg00qf 1536 32 a a DT cord-022526-j9kg00qf 1536 33 preventative preventative NN cord-022526-j9kg00qf 1536 34 for for IN cord-022526-j9kg00qf 1536 35 POI poi NN cord-022526-j9kg00qf 1536 36 in in IN cord-022526-j9kg00qf 1536 37 horses horse NNS cord-022526-j9kg00qf 1536 38 after after IN cord-022526-j9kg00qf 1536 39 small small JJ cord-022526-j9kg00qf 1536 40 intestinal intestinal JJ cord-022526-j9kg00qf 1536 41 surgery surgery NN cord-022526-j9kg00qf 1536 42 ( ( -LRB- cord-022526-j9kg00qf 1536 43 0.1 0.1 CD cord-022526-j9kg00qf 1536 44 mg mg NNP cord-022526-j9kg00qf 1536 45 / / SYM cord-022526-j9kg00qf 1536 46 kg kg NNP cord-022526-j9kg00qf 1536 47 body body NN cord-022526-j9kg00qf 1536 48 mass mass NN cord-022526-j9kg00qf 1536 49 intramuscularly intramuscularly RB cord-022526-j9kg00qf 1536 50 during during IN cord-022526-j9kg00qf 1536 51 the the DT cord-022526-j9kg00qf 1536 52 postoperative postoperative JJ cord-022526-j9kg00qf 1536 53 period period NN cord-022526-j9kg00qf 1536 54 ) ) -RRB- cord-022526-j9kg00qf 1536 55 . . . cord-022526-j9kg00qf 1537 1 [ [ -LRB- cord-022526-j9kg00qf 1537 2 50 50 CD cord-022526-j9kg00qf 1537 3 ] ] -RRB- cord-022526-j9kg00qf 1537 4 [ [ -LRB- cord-022526-j9kg00qf 1537 5 51 51 CD cord-022526-j9kg00qf 1537 6 ] ] -RRB- cord-022526-j9kg00qf 1537 7 [ [ -LRB- cord-022526-j9kg00qf 1537 8 52 52 CD cord-022526-j9kg00qf 1537 9 ] ] -RRB- cord-022526-j9kg00qf 1538 1 [ [ -LRB- cord-022526-j9kg00qf 1538 2 53 53 CD cord-022526-j9kg00qf 1538 3 ] ] -RRB- cord-022526-j9kg00qf 1539 1 The the DT cord-022526-j9kg00qf 1539 2 horse horse NN cord-022526-j9kg00qf 1539 3 erratically erratically RB cord-022526-j9kg00qf 1539 4 absorbs absorb VBZ cord-022526-j9kg00qf 1539 5 tablets tablet NNS cord-022526-j9kg00qf 1539 6 administered administer VBN cord-022526-j9kg00qf 1539 7 rectally rectally RB cord-022526-j9kg00qf 1539 8 , , , cord-022526-j9kg00qf 1539 9 but but CC cord-022526-j9kg00qf 1539 10 a a DT cord-022526-j9kg00qf 1539 11 method method NN cord-022526-j9kg00qf 1539 12 for for IN cord-022526-j9kg00qf 1539 13 preparing prepare VBG cord-022526-j9kg00qf 1539 14 a a DT cord-022526-j9kg00qf 1539 15 parenteral parenteral JJ cord-022526-j9kg00qf 1539 16 form form NN cord-022526-j9kg00qf 1539 17 of of IN cord-022526-j9kg00qf 1539 18 the the DT cord-022526-j9kg00qf 1539 19 drug drug NN cord-022526-j9kg00qf 1539 20 from from IN cord-022526-j9kg00qf 1539 21 tablets tablet NNS cord-022526-j9kg00qf 1539 22 has have VBZ cord-022526-j9kg00qf 1539 23 been be VBN cord-022526-j9kg00qf 1539 24 described describe VBN cord-022526-j9kg00qf 1539 25 . . . cord-022526-j9kg00qf 1540 1 54 54 CD cord-022526-j9kg00qf 1540 2 Cisapride Cisapride NNP cord-022526-j9kg00qf 1540 3 has have VBZ cord-022526-j9kg00qf 1540 4 the the DT cord-022526-j9kg00qf 1540 5 potential potential NN cord-022526-j9kg00qf 1540 6 to to TO cord-022526-j9kg00qf 1540 7 cause cause VB cord-022526-j9kg00qf 1540 8 adverse adverse JJ cord-022526-j9kg00qf 1540 9 cardiac cardiac JJ cord-022526-j9kg00qf 1540 10 side side NN cord-022526-j9kg00qf 1540 11 effects effect NNS cord-022526-j9kg00qf 1540 12 mediated mediate VBN cord-022526-j9kg00qf 1540 13 through through IN cord-022526-j9kg00qf 1540 14 blockage blockage NN cord-022526-j9kg00qf 1540 15 of of IN cord-022526-j9kg00qf 1540 16 the the DT cord-022526-j9kg00qf 1540 17 rapid rapid JJ cord-022526-j9kg00qf 1540 18 component component NN cord-022526-j9kg00qf 1540 19 of of IN cord-022526-j9kg00qf 1540 20 the the DT cord-022526-j9kg00qf 1540 21 delayed delay VBN cord-022526-j9kg00qf 1540 22 rectifier rectifier NN cord-022526-j9kg00qf 1540 23 potassium potassium NN cord-022526-j9kg00qf 1540 24 current current NN cord-022526-j9kg00qf 1540 25 that that WDT cord-022526-j9kg00qf 1540 26 include include VBP cord-022526-j9kg00qf 1540 27 lengthening lengthen VBG cord-022526-j9kg00qf 1540 28 of of IN cord-022526-j9kg00qf 1540 29 the the DT cord-022526-j9kg00qf 1540 30 QT QT NNP cord-022526-j9kg00qf 1540 31 interval interval NN cord-022526-j9kg00qf 1540 32 and and CC cord-022526-j9kg00qf 1540 33 development development NN cord-022526-j9kg00qf 1540 34 of of IN cord-022526-j9kg00qf 1540 35 torsades torsades NNP cord-022526-j9kg00qf 1540 36 de de FW cord-022526-j9kg00qf 1540 37 pointes pointes NNP cord-022526-j9kg00qf 1540 38 , , , cord-022526-j9kg00qf 1540 39 a a DT cord-022526-j9kg00qf 1540 40 potentially potentially RB cord-022526-j9kg00qf 1540 41 fatal fatal JJ cord-022526-j9kg00qf 1540 42 arrhythmia arrhythmia NN cord-022526-j9kg00qf 1540 43 . . . cord-022526-j9kg00qf 1541 1 These these DT cord-022526-j9kg00qf 1541 2 adverse adverse JJ cord-022526-j9kg00qf 1541 3 effects effect NNS cord-022526-j9kg00qf 1541 4 have have VBP cord-022526-j9kg00qf 1541 5 resulted result VBN cord-022526-j9kg00qf 1541 6 in in IN cord-022526-j9kg00qf 1541 7 withdrawal withdrawal NN cord-022526-j9kg00qf 1541 8 of of IN cord-022526-j9kg00qf 1541 9 the the DT cord-022526-j9kg00qf 1541 10 drug drug NN cord-022526-j9kg00qf 1541 11 in in IN cord-022526-j9kg00qf 1541 12 the the DT cord-022526-j9kg00qf 1541 13 United United NNP cord-022526-j9kg00qf 1541 14 States States NNP cord-022526-j9kg00qf 1541 15 . . . cord-022526-j9kg00qf 1542 1 Domperidone Domperidone NNP cord-022526-j9kg00qf 1542 2 acts act VBZ cord-022526-j9kg00qf 1542 3 as as IN cord-022526-j9kg00qf 1542 4 a a DT cord-022526-j9kg00qf 1542 5 competitive competitive JJ cord-022526-j9kg00qf 1542 6 antagonist antagonist NN cord-022526-j9kg00qf 1542 7 at at IN cord-022526-j9kg00qf 1542 8 peripheral peripheral JJ cord-022526-j9kg00qf 1542 9 DA DA NNP cord-022526-j9kg00qf 1542 10 2 2 CD cord-022526-j9kg00qf 1542 11 receptors receptor NNS cord-022526-j9kg00qf 1542 12 . . . cord-022526-j9kg00qf 1543 1 The the DT cord-022526-j9kg00qf 1543 2 drug drug NN cord-022526-j9kg00qf 1543 3 is be VBZ cord-022526-j9kg00qf 1543 4 a a DT cord-022526-j9kg00qf 1543 5 therapeutic therapeutic JJ cord-022526-j9kg00qf 1543 6 agent agent NN cord-022526-j9kg00qf 1543 7 ( ( -LRB- cord-022526-j9kg00qf 1543 8 1.1 1.1 CD cord-022526-j9kg00qf 1543 9 mg mg NNP cord-022526-j9kg00qf 1543 10 / / SYM cord-022526-j9kg00qf 1543 11 kg kg NNP cord-022526-j9kg00qf 1543 12 / / SYM cord-022526-j9kg00qf 1543 13 day day NN cord-022526-j9kg00qf 1543 14 ) ) -RRB- cord-022526-j9kg00qf 1543 15 for for IN cord-022526-j9kg00qf 1543 16 mares mare NNS cord-022526-j9kg00qf 1543 17 grazing graze VBG cord-022526-j9kg00qf 1543 18 endophyte endophyte NN cord-022526-j9kg00qf 1543 19 - - HYPH cord-022526-j9kg00qf 1543 20 infected infect VBN cord-022526-j9kg00qf 1543 21 tall tall JJ cord-022526-j9kg00qf 1543 22 fescue fescue NN cord-022526-j9kg00qf 1543 23 , , , cord-022526-j9kg00qf 1543 24 principally principally RB cord-022526-j9kg00qf 1543 25 because because IN cord-022526-j9kg00qf 1543 26 of of IN cord-022526-j9kg00qf 1543 27 drug drug NN cord-022526-j9kg00qf 1543 28 - - HYPH cord-022526-j9kg00qf 1543 29 enhanced enhance VBN cord-022526-j9kg00qf 1543 30 prolactin prolactin NN cord-022526-j9kg00qf 1543 31 release release NN cord-022526-j9kg00qf 1543 32 . . . cord-022526-j9kg00qf 1544 1 The the DT cord-022526-j9kg00qf 1544 2 potential potential JJ cord-022526-j9kg00qf 1544 3 prokinetic prokinetic JJ cord-022526-j9kg00qf 1544 4 effects effect NNS cord-022526-j9kg00qf 1544 5 of of IN cord-022526-j9kg00qf 1544 6 domperidone domperidone NN cord-022526-j9kg00qf 1544 7 have have VBP cord-022526-j9kg00qf 1544 8 not not RB cord-022526-j9kg00qf 1544 9 been be VBN cord-022526-j9kg00qf 1544 10 studied study VBN cord-022526-j9kg00qf 1544 11 extensively extensively RB cord-022526-j9kg00qf 1544 12 in in IN cord-022526-j9kg00qf 1544 13 horses horse NNS cord-022526-j9kg00qf 1544 14 , , , cord-022526-j9kg00qf 1544 15 but but CC cord-022526-j9kg00qf 1544 16 a a DT cord-022526-j9kg00qf 1544 17 modest modest JJ cord-022526-j9kg00qf 1544 18 efficacy efficacy NN cord-022526-j9kg00qf 1544 19 of of IN cord-022526-j9kg00qf 1544 20 domperidone domperidone NNP cord-022526-j9kg00qf 1544 21 ( ( -LRB- cord-022526-j9kg00qf 1544 22 0.2 0.2 CD cord-022526-j9kg00qf 1544 23 mg mg NNP cord-022526-j9kg00qf 1544 24 / / SYM cord-022526-j9kg00qf 1544 25 kg kg NNP cord-022526-j9kg00qf 1544 26 intravenously intravenously RB cord-022526-j9kg00qf 1544 27 ) ) -RRB- cord-022526-j9kg00qf 1544 28 has have VBZ cord-022526-j9kg00qf 1544 29 been be VBN cord-022526-j9kg00qf 1544 30 demonstrated demonstrate VBN cord-022526-j9kg00qf 1544 31 in in IN cord-022526-j9kg00qf 1544 32 experimental experimental JJ cord-022526-j9kg00qf 1544 33 ileus ileus NN cord-022526-j9kg00qf 1544 34 in in IN cord-022526-j9kg00qf 1544 35 two two CD cord-022526-j9kg00qf 1544 36 ponies pony NNS cord-022526-j9kg00qf 1544 37 . . . cord-022526-j9kg00qf 1545 1 Erythromycin Erythromycin NNP cord-022526-j9kg00qf 1545 2 is be VBZ cord-022526-j9kg00qf 1545 3 a a DT cord-022526-j9kg00qf 1545 4 direct direct JJ cord-022526-j9kg00qf 1545 5 motilin motilin NN cord-022526-j9kg00qf 1545 6 receptor receptor NN cord-022526-j9kg00qf 1545 7 agonist agonist NN cord-022526-j9kg00qf 1545 8 on on IN cord-022526-j9kg00qf 1545 9 smooth smooth JJ cord-022526-j9kg00qf 1545 10 muscle muscle NN cord-022526-j9kg00qf 1545 11 cells cell NNS cord-022526-j9kg00qf 1545 12 and and CC cord-022526-j9kg00qf 1545 13 also also RB cord-022526-j9kg00qf 1545 14 may may MD cord-022526-j9kg00qf 1545 15 act act VB cord-022526-j9kg00qf 1545 16 within within IN cord-022526-j9kg00qf 1545 17 the the DT cord-022526-j9kg00qf 1545 18 enteric enteric JJ cord-022526-j9kg00qf 1545 19 nervous nervous JJ cord-022526-j9kg00qf 1545 20 system system NN cord-022526-j9kg00qf 1545 21 to to TO cord-022526-j9kg00qf 1545 22 facilitate facilitate VB cord-022526-j9kg00qf 1545 23 the the DT cord-022526-j9kg00qf 1545 24 release release NN cord-022526-j9kg00qf 1545 25 of of IN cord-022526-j9kg00qf 1545 26 acetylcholine acetylcholine NN cord-022526-j9kg00qf 1545 27 and and CC cord-022526-j9kg00qf 1545 28 motilin motilin NN cord-022526-j9kg00qf 1545 29 . . . cord-022526-j9kg00qf 1546 1 Erythromycin erythromycin NN cord-022526-j9kg00qf 1546 2 enhances enhance VBZ cord-022526-j9kg00qf 1546 3 gastric gastric JJ cord-022526-j9kg00qf 1546 4 emptying emptying NN cord-022526-j9kg00qf 1546 5 in in IN cord-022526-j9kg00qf 1546 6 normal normal JJ cord-022526-j9kg00qf 1546 7 horses horse NNS cord-022526-j9kg00qf 1546 8 but but CC cord-022526-j9kg00qf 1546 9 has have VBZ cord-022526-j9kg00qf 1546 10 a a DT cord-022526-j9kg00qf 1546 11 more more RBR cord-022526-j9kg00qf 1546 12 pronounced pronounced JJ cord-022526-j9kg00qf 1546 13 effect effect NN cord-022526-j9kg00qf 1546 14 on on IN cord-022526-j9kg00qf 1546 15 the the DT cord-022526-j9kg00qf 1546 16 hindgut hindgut NN cord-022526-j9kg00qf 1546 17 . . . cord-022526-j9kg00qf 1547 1 47 47 CD cord-022526-j9kg00qf 1547 2 , , , cord-022526-j9kg00qf 1547 3 55 55 CD cord-022526-j9kg00qf 1547 4 Erythromycin erythromycin NN cord-022526-j9kg00qf 1547 5 lactobionate lactobionate NN cord-022526-j9kg00qf 1547 6 ( ( -LRB- cord-022526-j9kg00qf 1547 7 1.0 1.0 CD cord-022526-j9kg00qf 1547 8 mg mg NNP cord-022526-j9kg00qf 1547 9 / / SYM cord-022526-j9kg00qf 1547 10 kg kg NNP cord-022526-j9kg00qf 1547 11 intravenously intravenously RB cord-022526-j9kg00qf 1547 12 ) ) -RRB- cord-022526-j9kg00qf 1547 13 hastens hasten VBZ cord-022526-j9kg00qf 1547 14 cecal cecal JJ cord-022526-j9kg00qf 1547 15 emptying emptying NN cord-022526-j9kg00qf 1547 16 in in IN cord-022526-j9kg00qf 1547 17 normal normal JJ cord-022526-j9kg00qf 1547 18 animals animal NNS cord-022526-j9kg00qf 1547 19 and and CC cord-022526-j9kg00qf 1547 20 induces induce VBZ cord-022526-j9kg00qf 1547 21 colonic colonic JJ cord-022526-j9kg00qf 1547 22 MMC mmc NN cord-022526-j9kg00qf 1547 23 - - HYPH cord-022526-j9kg00qf 1547 24 like like JJ cord-022526-j9kg00qf 1547 25 activity activity NN cord-022526-j9kg00qf 1547 26 across across IN cord-022526-j9kg00qf 1547 27 the the DT cord-022526-j9kg00qf 1547 28 colon colon NN cord-022526-j9kg00qf 1547 29 . . . cord-022526-j9kg00qf 1548 1 Administration administration NN cord-022526-j9kg00qf 1548 2 often often RB cord-022526-j9kg00qf 1548 3 is be VBZ cord-022526-j9kg00qf 1548 4 associated associate VBN cord-022526-j9kg00qf 1548 5 with with IN cord-022526-j9kg00qf 1548 6 defecation defecation NN cord-022526-j9kg00qf 1548 7 and and CC cord-022526-j9kg00qf 1548 8 abdominal abdominal JJ cord-022526-j9kg00qf 1548 9 discomfort discomfort NN cord-022526-j9kg00qf 1548 10 . . . cord-022526-j9kg00qf 1549 1 The the DT cord-022526-j9kg00qf 1549 2 drug drug NN cord-022526-j9kg00qf 1549 3 may may MD cord-022526-j9kg00qf 1549 4 help help VB cord-022526-j9kg00qf 1549 5 prevent prevent VB cord-022526-j9kg00qf 1549 6 cecal cecal JJ cord-022526-j9kg00qf 1549 7 impaction impaction NN cord-022526-j9kg00qf 1549 8 in in IN cord-022526-j9kg00qf 1549 9 horses horse NNS cord-022526-j9kg00qf 1549 10 after after IN cord-022526-j9kg00qf 1549 11 anesthesia anesthesia NN cord-022526-j9kg00qf 1549 12 , , , cord-022526-j9kg00qf 1549 13 although although IN cord-022526-j9kg00qf 1549 14 its -PRON- PRP$ cord-022526-j9kg00qf 1549 15 effectiveness effectiveness NN cord-022526-j9kg00qf 1549 16 on on IN cord-022526-j9kg00qf 1549 17 cecal cecal JJ cord-022526-j9kg00qf 1549 18 motility motility NN cord-022526-j9kg00qf 1549 19 in in IN cord-022526-j9kg00qf 1549 20 the the DT cord-022526-j9kg00qf 1549 21 immediate immediate JJ cord-022526-j9kg00qf 1549 22 postoperative postoperative JJ cord-022526-j9kg00qf 1549 23 period period NN cord-022526-j9kg00qf 1549 24 may may MD cord-022526-j9kg00qf 1549 25 be be VB cord-022526-j9kg00qf 1549 26 reduced reduce VBN cord-022526-j9kg00qf 1549 27 . . . cord-022526-j9kg00qf 1550 1 36 36 CD cord-022526-j9kg00qf 1550 2 High high JJ cord-022526-j9kg00qf 1550 3 doses dose NNS cord-022526-j9kg00qf 1550 4 , , , cord-022526-j9kg00qf 1550 5 constant constant JJ cord-022526-j9kg00qf 1550 6 infusion infusion NN cord-022526-j9kg00qf 1550 7 , , , cord-022526-j9kg00qf 1550 8 or or CC cord-022526-j9kg00qf 1550 9 prolonged prolong VBN cord-022526-j9kg00qf 1550 10 use use NN cord-022526-j9kg00qf 1550 11 of of IN cord-022526-j9kg00qf 1550 12 erythromycin erythromycin NN cord-022526-j9kg00qf 1550 13 induces induce VBZ cord-022526-j9kg00qf 1550 14 receptor receptor NN cord-022526-j9kg00qf 1550 15 downregulation downregulation NN cord-022526-j9kg00qf 1550 16 and and CC cord-022526-j9kg00qf 1550 17 inhibition inhibition NN cord-022526-j9kg00qf 1550 18 of of IN cord-022526-j9kg00qf 1550 19 activity activity NN cord-022526-j9kg00qf 1550 20 . . . cord-022526-j9kg00qf 1551 1 Erythromycin Erythromycin NNP cord-022526-j9kg00qf 1551 2 can can MD cord-022526-j9kg00qf 1551 3 induce induce VB cord-022526-j9kg00qf 1551 4 diarrhea diarrhea NN cord-022526-j9kg00qf 1551 5 in in IN cord-022526-j9kg00qf 1551 6 adults adult NNS cord-022526-j9kg00qf 1551 7 , , , cord-022526-j9kg00qf 1551 8 therefore therefore RB cord-022526-j9kg00qf 1551 9 one one PRP cord-022526-j9kg00qf 1551 10 should should MD cord-022526-j9kg00qf 1551 11 avoid avoid VB cord-022526-j9kg00qf 1551 12 dosing dose VBG cord-022526-j9kg00qf 1551 13 over over IN cord-022526-j9kg00qf 1551 14 many many JJ cord-022526-j9kg00qf 1551 15 days day NNS cord-022526-j9kg00qf 1551 16 . . . cord-022526-j9kg00qf 1552 1 Naloxone Naloxone NNP cord-022526-j9kg00qf 1552 2 ( ( -LRB- cord-022526-j9kg00qf 1552 3 0.05 0.05 CD cord-022526-j9kg00qf 1552 4 mg mg NNP cord-022526-j9kg00qf 1552 5 / / SYM cord-022526-j9kg00qf 1552 6 kg kg NNP cord-022526-j9kg00qf 1552 7 intravenously intravenously RB cord-022526-j9kg00qf 1552 8 ) ) -RRB- cord-022526-j9kg00qf 1552 9 induces induce VBZ cord-022526-j9kg00qf 1552 10 contractile contractile JJ cord-022526-j9kg00qf 1552 11 activity activity NN cord-022526-j9kg00qf 1552 12 in in IN cord-022526-j9kg00qf 1552 13 the the DT cord-022526-j9kg00qf 1552 14 cecum cecum NN cord-022526-j9kg00qf 1552 15 and and CC cord-022526-j9kg00qf 1552 16 left leave VBD cord-022526-j9kg00qf 1552 17 colon colon NN cord-022526-j9kg00qf 1552 18 . . . cord-022526-j9kg00qf 1553 1 56 56 CD cord-022526-j9kg00qf 1553 2 Defecation defecation NN cord-022526-j9kg00qf 1553 3 commonly commonly RB cord-022526-j9kg00qf 1553 4 follows follow VBZ cord-022526-j9kg00qf 1553 5 administration administration NN cord-022526-j9kg00qf 1553 6 of of IN cord-022526-j9kg00qf 1553 7 naloxone naloxone NN cord-022526-j9kg00qf 1553 8 within within IN cord-022526-j9kg00qf 1553 9 15 15 CD cord-022526-j9kg00qf 1553 10 to to TO cord-022526-j9kg00qf 1553 11 20 20 CD cord-022526-j9kg00qf 1553 12 minutes minute NNS cord-022526-j9kg00qf 1553 13 . . . cord-022526-j9kg00qf 1554 1 α α NNP cord-022526-j9kg00qf 1554 2 2 2 CD cord-022526-j9kg00qf 1554 3 -Adrenoreceptor -Adrenoreceptor NNP cord-022526-j9kg00qf 1554 4 antagonists antagonist NNS cord-022526-j9kg00qf 1554 5 such such JJ cord-022526-j9kg00qf 1554 6 as as IN cord-022526-j9kg00qf 1554 7 yohimbine yohimbine NN cord-022526-j9kg00qf 1554 8 or or CC cord-022526-j9kg00qf 1554 9 tolazoline tolazoline NN cord-022526-j9kg00qf 1554 10 counteract counteract VB cord-022526-j9kg00qf 1554 11 increased increase VBN cord-022526-j9kg00qf 1554 12 sympathetic sympathetic JJ cord-022526-j9kg00qf 1554 13 outflow outflow NN cord-022526-j9kg00qf 1554 14 in in IN cord-022526-j9kg00qf 1554 15 response response NN cord-022526-j9kg00qf 1554 16 to to IN cord-022526-j9kg00qf 1554 17 nociceptive nociceptive JJ cord-022526-j9kg00qf 1554 18 stimulation stimulation NN cord-022526-j9kg00qf 1554 19 . . . cord-022526-j9kg00qf 1555 1 Yohimbine yohimbine NN cord-022526-j9kg00qf 1555 2 infusion infusion NN cord-022526-j9kg00qf 1555 3 ( ( -LRB- cord-022526-j9kg00qf 1555 4 75 75 CD cord-022526-j9kg00qf 1555 5 µg µg NN cord-022526-j9kg00qf 1555 6 / / SYM cord-022526-j9kg00qf 1555 7 kg kg NN cord-022526-j9kg00qf 1555 8 ) ) -RRB- cord-022526-j9kg00qf 1555 9 also also RB cord-022526-j9kg00qf 1555 10 may may MD cord-022526-j9kg00qf 1555 11 attenuate attenuate VB cord-022526-j9kg00qf 1555 12 the the DT cord-022526-j9kg00qf 1555 13 negative negative JJ cord-022526-j9kg00qf 1555 14 effects effect NNS cord-022526-j9kg00qf 1555 15 of of IN cord-022526-j9kg00qf 1555 16 endotoxin endotoxin NN cord-022526-j9kg00qf 1555 17 on on IN cord-022526-j9kg00qf 1555 18 motility motility NN cord-022526-j9kg00qf 1555 19 . . . cord-022526-j9kg00qf 1556 1 32 32 CD cord-022526-j9kg00qf 1556 2 Intravenous intravenous JJ cord-022526-j9kg00qf 1556 3 infusion infusion NN cord-022526-j9kg00qf 1556 4 of of IN cord-022526-j9kg00qf 1556 5 lidocaine lidocaine NN cord-022526-j9kg00qf 1556 6 may may MD cord-022526-j9kg00qf 1556 7 suppress suppress VB cord-022526-j9kg00qf 1556 8 primary primary JJ cord-022526-j9kg00qf 1556 9 afferent afferent JJ cord-022526-j9kg00qf 1556 10 neurons neuron NNS cord-022526-j9kg00qf 1556 11 , , , cord-022526-j9kg00qf 1556 12 thereby thereby RB cord-022526-j9kg00qf 1556 13 limiting limit VBG cord-022526-j9kg00qf 1556 14 reflex reflex JJ cord-022526-j9kg00qf 1556 15 efferent efferent JJ cord-022526-j9kg00qf 1556 16 inhibition inhibition NN cord-022526-j9kg00qf 1556 17 of of IN cord-022526-j9kg00qf 1556 18 motility motility NN cord-022526-j9kg00qf 1556 19 . . . cord-022526-j9kg00qf 1557 1 An an DT cord-022526-j9kg00qf 1557 2 infusion infusion NN cord-022526-j9kg00qf 1557 3 dose dose NN cord-022526-j9kg00qf 1557 4 of of IN cord-022526-j9kg00qf 1557 5 15 15 CD cord-022526-j9kg00qf 1557 6 to to TO cord-022526-j9kg00qf 1557 7 20 20 CD cord-022526-j9kg00qf 1557 8 mg mg NNP cord-022526-j9kg00qf 1557 9 / / SYM cord-022526-j9kg00qf 1557 10 min min NN cord-022526-j9kg00qf 1557 11 over over IN cord-022526-j9kg00qf 1557 12 5 5 CD cord-022526-j9kg00qf 1557 13 to to TO cord-022526-j9kg00qf 1557 14 6 6 CD cord-022526-j9kg00qf 1557 15 hours hour NNS cord-022526-j9kg00qf 1557 16 has have VBZ cord-022526-j9kg00qf 1557 17 been be VBN cord-022526-j9kg00qf 1557 18 recommended recommend VBN cord-022526-j9kg00qf 1557 19 for for IN cord-022526-j9kg00qf 1557 20 horses horse NNS cord-022526-j9kg00qf 1557 21 . . . cord-022526-j9kg00qf 1558 1 Lidocaine lidocaine NN cord-022526-j9kg00qf 1558 2 infusion infusion NN cord-022526-j9kg00qf 1558 3 is be VBZ cord-022526-j9kg00qf 1558 4 associated associate VBN cord-022526-j9kg00qf 1558 5 with with IN cord-022526-j9kg00qf 1558 6 reversible reversible JJ cord-022526-j9kg00qf 1558 7 side side NN cord-022526-j9kg00qf 1558 8 effects effect NNS cord-022526-j9kg00qf 1558 9 that that WDT cord-022526-j9kg00qf 1558 10 include include VBP cord-022526-j9kg00qf 1558 11 muscle muscle NN cord-022526-j9kg00qf 1558 12 fasciculations fasciculation NNS cord-022526-j9kg00qf 1558 13 , , , cord-022526-j9kg00qf 1558 14 ataxia ataxia NN cord-022526-j9kg00qf 1558 15 , , , cord-022526-j9kg00qf 1558 16 and and CC cord-022526-j9kg00qf 1558 17 seizure seizure NN cord-022526-j9kg00qf 1558 18 . . . cord-022526-j9kg00qf 1559 1 Consequently consequently RB cord-022526-j9kg00qf 1559 2 , , , cord-022526-j9kg00qf 1559 3 the the DT cord-022526-j9kg00qf 1559 4 rate rate NN cord-022526-j9kg00qf 1559 5 of of IN cord-022526-j9kg00qf 1559 6 infusion infusion NN cord-022526-j9kg00qf 1559 7 requires require VBZ cord-022526-j9kg00qf 1559 8 close close JJ cord-022526-j9kg00qf 1559 9 monitoring monitoring NN cord-022526-j9kg00qf 1559 10 . . . cord-022526-j9kg00qf 1559 11 _SP cord-022526-j9kg00qf 1560 1 Katharina Katharina NNP cord-022526-j9kg00qf 1560 2 L. L. NNP cord-022526-j9kg00qf 1560 3 Lohmann Lohmann NNP cord-022526-j9kg00qf 1560 4 , , , cord-022526-j9kg00qf 1560 5 Michelle Michelle NNP cord-022526-j9kg00qf 1560 6 Henry Henry NNP cord-022526-j9kg00qf 1560 7 Barton Barton NNP cord-022526-j9kg00qf 1560 8 Endotoxemia Endotoxemia NNP cord-022526-j9kg00qf 1560 9 is be VBZ cord-022526-j9kg00qf 1560 10 defined define VBN cord-022526-j9kg00qf 1560 11 as as IN cord-022526-j9kg00qf 1560 12 the the DT cord-022526-j9kg00qf 1560 13 presence presence NN cord-022526-j9kg00qf 1560 14 of of IN cord-022526-j9kg00qf 1560 15 endotoxin endotoxin NN cord-022526-j9kg00qf 1560 16 in in IN cord-022526-j9kg00qf 1560 17 the the DT cord-022526-j9kg00qf 1560 18 bloodstream bloodstream NN cord-022526-j9kg00qf 1560 19 . . . cord-022526-j9kg00qf 1561 1 Most most RBS cord-022526-j9kg00qf 1561 2 often often RB cord-022526-j9kg00qf 1561 3 , , , cord-022526-j9kg00qf 1561 4 however however RB cord-022526-j9kg00qf 1561 5 , , , cord-022526-j9kg00qf 1561 6 the the DT cord-022526-j9kg00qf 1561 7 term term NN cord-022526-j9kg00qf 1561 8 is be VBZ cord-022526-j9kg00qf 1561 9 used use VBN cord-022526-j9kg00qf 1561 10 to to TO cord-022526-j9kg00qf 1561 11 refer refer VB cord-022526-j9kg00qf 1561 12 to to IN cord-022526-j9kg00qf 1561 13 the the DT cord-022526-j9kg00qf 1561 14 associated associate VBN cord-022526-j9kg00qf 1561 15 clinical clinical JJ cord-022526-j9kg00qf 1561 16 manifestations manifestation NNS cord-022526-j9kg00qf 1561 17 caused cause VBN cord-022526-j9kg00qf 1561 18 by by IN cord-022526-j9kg00qf 1561 19 an an DT cord-022526-j9kg00qf 1561 20 overshooting overshoot VBG cord-022526-j9kg00qf 1561 21 inflammatory inflammatory JJ cord-022526-j9kg00qf 1561 22 reaction reaction NN cord-022526-j9kg00qf 1561 23 . . . cord-022526-j9kg00qf 1562 1 In in IN cord-022526-j9kg00qf 1562 2 its -PRON- PRP$ cord-022526-j9kg00qf 1562 3 pathophysiologic pathophysiologic NN cord-022526-j9kg00qf 1562 4 consequences consequence VBZ cord-022526-j9kg00qf 1562 5 the the DT cord-022526-j9kg00qf 1562 6 innate innate JJ cord-022526-j9kg00qf 1562 7 immune immune JJ cord-022526-j9kg00qf 1562 8 response response NN cord-022526-j9kg00qf 1562 9 to to IN cord-022526-j9kg00qf 1562 10 endotoxin endotoxin NN cord-022526-j9kg00qf 1562 11 ( ( -LRB- cord-022526-j9kg00qf 1562 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1562 13 ) ) -RRB- cord-022526-j9kg00qf 1562 14 is be VBZ cord-022526-j9kg00qf 1562 15 similar similar JJ cord-022526-j9kg00qf 1562 16 to to IN cord-022526-j9kg00qf 1562 17 the the DT cord-022526-j9kg00qf 1562 18 response response NN cord-022526-j9kg00qf 1562 19 to to IN cord-022526-j9kg00qf 1562 20 other other JJ cord-022526-j9kg00qf 1562 21 stimuli stimulus NNS cord-022526-j9kg00qf 1562 22 ; ; : cord-022526-j9kg00qf 1562 23 for for IN cord-022526-j9kg00qf 1562 24 example example NN cord-022526-j9kg00qf 1562 25 , , , cord-022526-j9kg00qf 1562 26 overwhelming overwhelming JJ cord-022526-j9kg00qf 1562 27 bacterial bacterial JJ cord-022526-j9kg00qf 1562 28 infection infection NN cord-022526-j9kg00qf 1562 29 , , , cord-022526-j9kg00qf 1562 30 viral viral JJ cord-022526-j9kg00qf 1562 31 infection infection NN cord-022526-j9kg00qf 1562 32 , , , cord-022526-j9kg00qf 1562 33 or or CC cord-022526-j9kg00qf 1562 34 severe severe JJ cord-022526-j9kg00qf 1562 35 trauma trauma NN cord-022526-j9kg00qf 1562 36 . . . cord-022526-j9kg00qf 1563 1 The the DT cord-022526-j9kg00qf 1563 2 term term NN cord-022526-j9kg00qf 1563 3 systemic systemic JJ cord-022526-j9kg00qf 1563 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 1563 5 response response NN cord-022526-j9kg00qf 1563 6 syndrome syndrome NN cord-022526-j9kg00qf 1563 7 therefore therefore RB cord-022526-j9kg00qf 1563 8 was be VBD cord-022526-j9kg00qf 1563 9 introduced introduce VBN cord-022526-j9kg00qf 1563 10 to to TO cord-022526-j9kg00qf 1563 11 describe describe VB cord-022526-j9kg00qf 1563 12 a a DT cord-022526-j9kg00qf 1563 13 general general JJ cord-022526-j9kg00qf 1563 14 systemic systemic JJ cord-022526-j9kg00qf 1563 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 1563 16 process process NN cord-022526-j9kg00qf 1563 17 independent independent JJ cord-022526-j9kg00qf 1563 18 of of IN cord-022526-j9kg00qf 1563 19 cause cause NN cord-022526-j9kg00qf 1563 20 . . . cord-022526-j9kg00qf 1564 1 Sepsis sepsis NN cord-022526-j9kg00qf 1564 2 is be VBZ cord-022526-j9kg00qf 1564 3 defined define VBN cord-022526-j9kg00qf 1564 4 as as IN cord-022526-j9kg00qf 1564 5 the the DT cord-022526-j9kg00qf 1564 6 " " `` cord-022526-j9kg00qf 1564 7 systemic systemic JJ cord-022526-j9kg00qf 1564 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 1564 9 response response NN cord-022526-j9kg00qf 1564 10 to to IN cord-022526-j9kg00qf 1564 11 infection infection NN cord-022526-j9kg00qf 1564 12 , , , cord-022526-j9kg00qf 1564 13 " " '' cord-022526-j9kg00qf 1564 14 and and CC cord-022526-j9kg00qf 1564 15 septic septic JJ cord-022526-j9kg00qf 1564 16 shock shock NN cord-022526-j9kg00qf 1564 17 as as IN cord-022526-j9kg00qf 1564 18 " " `` cord-022526-j9kg00qf 1564 19 sepsis sepsis NN cord-022526-j9kg00qf 1564 20 - - HYPH cord-022526-j9kg00qf 1564 21 induced induce VBN cord-022526-j9kg00qf 1564 22 hypotension hypotension NN cord-022526-j9kg00qf 1564 23 , , , cord-022526-j9kg00qf 1564 24 persisting persist VBG cord-022526-j9kg00qf 1564 25 despite despite IN cord-022526-j9kg00qf 1564 26 adequate adequate JJ cord-022526-j9kg00qf 1564 27 fluid fluid JJ cord-022526-j9kg00qf 1564 28 resuscitation resuscitation NN cord-022526-j9kg00qf 1564 29 , , , cord-022526-j9kg00qf 1564 30 along along IN cord-022526-j9kg00qf 1564 31 with with IN cord-022526-j9kg00qf 1564 32 the the DT cord-022526-j9kg00qf 1564 33 presence presence NN cord-022526-j9kg00qf 1564 34 of of IN cord-022526-j9kg00qf 1564 35 hypoperfusion hypoperfusion NN cord-022526-j9kg00qf 1564 36 abnormalities abnormality NNS cord-022526-j9kg00qf 1564 37 or or CC cord-022526-j9kg00qf 1564 38 organ organ NN cord-022526-j9kg00qf 1564 39 dysfunction dysfunction NN cord-022526-j9kg00qf 1564 40 . . . cord-022526-j9kg00qf 1565 1 " " `` cord-022526-j9kg00qf 1565 2 1 1 CD cord-022526-j9kg00qf 1566 1 According accord VBG cord-022526-j9kg00qf 1566 2 to to IN cord-022526-j9kg00qf 1566 3 these these DT cord-022526-j9kg00qf 1566 4 definitions definition NNS cord-022526-j9kg00qf 1566 5 the the DT cord-022526-j9kg00qf 1566 6 diagnosis diagnosis NN cord-022526-j9kg00qf 1566 7 of of IN cord-022526-j9kg00qf 1566 8 sepsis sepsis NN cord-022526-j9kg00qf 1566 9 requires require VBZ cord-022526-j9kg00qf 1566 10 documentation documentation NN cord-022526-j9kg00qf 1566 11 of of IN cord-022526-j9kg00qf 1566 12 infection infection NN cord-022526-j9kg00qf 1566 13 by by IN cord-022526-j9kg00qf 1566 14 culture culture NN cord-022526-j9kg00qf 1566 15 in in IN cord-022526-j9kg00qf 1566 16 addition addition NN cord-022526-j9kg00qf 1566 17 to to IN cord-022526-j9kg00qf 1566 18 two two CD cord-022526-j9kg00qf 1566 19 or or CC cord-022526-j9kg00qf 1566 20 more more JJR cord-022526-j9kg00qf 1566 21 of of IN cord-022526-j9kg00qf 1566 22 the the DT cord-022526-j9kg00qf 1566 23 following follow VBG cord-022526-j9kg00qf 1566 24 findings finding NNS cord-022526-j9kg00qf 1566 25 : : : cord-022526-j9kg00qf 1566 26 hypo hypo NN cord-022526-j9kg00qf 1566 27 - - : cord-022526-j9kg00qf 1566 28 or or CC cord-022526-j9kg00qf 1566 29 hyperthermia hyperthermia NN cord-022526-j9kg00qf 1566 30 , , , cord-022526-j9kg00qf 1566 31 tachycardia tachycardia NN cord-022526-j9kg00qf 1566 32 , , , cord-022526-j9kg00qf 1566 33 tachypnea tachypnea NNP cord-022526-j9kg00qf 1566 34 or or CC cord-022526-j9kg00qf 1566 35 hypocapnia hypocapnia NNP cord-022526-j9kg00qf 1566 36 , , , cord-022526-j9kg00qf 1566 37 and and CC cord-022526-j9kg00qf 1566 38 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 1566 39 , , , cord-022526-j9kg00qf 1566 40 leukopenia leukopenia NN cord-022526-j9kg00qf 1566 41 , , , cord-022526-j9kg00qf 1566 42 or or CC cord-022526-j9kg00qf 1566 43 an an DT cord-022526-j9kg00qf 1566 44 increased increase VBN cord-022526-j9kg00qf 1566 45 proportion proportion NN cord-022526-j9kg00qf 1566 46 of of IN cord-022526-j9kg00qf 1566 47 immature immature JJ cord-022526-j9kg00qf 1566 48 leukocyte leukocyte NN cord-022526-j9kg00qf 1566 49 forms form NNS cord-022526-j9kg00qf 1566 50 . . . cord-022526-j9kg00qf 1567 1 Organ organ NN cord-022526-j9kg00qf 1567 2 failure failure NN cord-022526-j9kg00qf 1567 3 is be VBZ cord-022526-j9kg00qf 1567 4 a a DT cord-022526-j9kg00qf 1567 5 common common JJ cord-022526-j9kg00qf 1567 6 sequela sequela NN cord-022526-j9kg00qf 1567 7 of of IN cord-022526-j9kg00qf 1567 8 endotoxic endotoxic JJ cord-022526-j9kg00qf 1567 9 or or CC cord-022526-j9kg00qf 1567 10 septic septic JJ cord-022526-j9kg00qf 1567 11 shock shock NN cord-022526-j9kg00qf 1567 12 , , , cord-022526-j9kg00qf 1567 13 and and CC cord-022526-j9kg00qf 1567 14 the the DT cord-022526-j9kg00qf 1567 15 term term NN cord-022526-j9kg00qf 1567 16 multiple multiple JJ cord-022526-j9kg00qf 1567 17 organ organ NN cord-022526-j9kg00qf 1567 18 dysfunction dysfunction NN cord-022526-j9kg00qf 1567 19 syndrome syndrome NN cord-022526-j9kg00qf 1567 20 describes describe VBZ cord-022526-j9kg00qf 1567 21 insufficiency insufficiency NN cord-022526-j9kg00qf 1567 22 of of IN cord-022526-j9kg00qf 1567 23 two two CD cord-022526-j9kg00qf 1567 24 or or CC cord-022526-j9kg00qf 1567 25 more more JJR cord-022526-j9kg00qf 1567 26 organ organ NN cord-022526-j9kg00qf 1567 27 systems system NNS cord-022526-j9kg00qf 1567 28 , , , cord-022526-j9kg00qf 1567 29 as as IN cord-022526-j9kg00qf 1567 30 evident evident JJ cord-022526-j9kg00qf 1567 31 by by IN cord-022526-j9kg00qf 1567 32 clinical clinical JJ cord-022526-j9kg00qf 1567 33 or or CC cord-022526-j9kg00qf 1567 34 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 1567 35 changes change NNS cord-022526-j9kg00qf 1567 36 . . . cord-022526-j9kg00qf 1568 1 In in IN cord-022526-j9kg00qf 1568 2 horses horse NNS cord-022526-j9kg00qf 1568 3 one one PRP cord-022526-j9kg00qf 1568 4 should should MD cord-022526-j9kg00qf 1568 5 include include VB cord-022526-j9kg00qf 1568 6 the the DT cord-022526-j9kg00qf 1568 7 laminae laminae NN cord-022526-j9kg00qf 1568 8 of of IN cord-022526-j9kg00qf 1568 9 the the DT cord-022526-j9kg00qf 1568 10 feet foot NNS cord-022526-j9kg00qf 1568 11 in in IN cord-022526-j9kg00qf 1568 12 the the DT cord-022526-j9kg00qf 1568 13 list list NN cord-022526-j9kg00qf 1568 14 of of IN cord-022526-j9kg00qf 1568 15 organs organ NNS cord-022526-j9kg00qf 1568 16 susceptible susceptible JJ cord-022526-j9kg00qf 1568 17 to to IN cord-022526-j9kg00qf 1568 18 failure failure NN cord-022526-j9kg00qf 1568 19 . . . cord-022526-j9kg00qf 1569 1 German german JJ cord-022526-j9kg00qf 1569 2 scientist scientist NN cord-022526-j9kg00qf 1569 3 Richard Richard NNP cord-022526-j9kg00qf 1569 4 Pfeiffer Pfeiffer NNP cord-022526-j9kg00qf 1569 5 ( ( -LRB- cord-022526-j9kg00qf 1569 6 1858 1858 CD cord-022526-j9kg00qf 1569 7 - - SYM cord-022526-j9kg00qf 1569 8 1945 1945 CD cord-022526-j9kg00qf 1569 9 ) ) -RRB- cord-022526-j9kg00qf 1569 10 , , , cord-022526-j9kg00qf 1569 11 in in IN cord-022526-j9kg00qf 1569 12 working work VBG cord-022526-j9kg00qf 1569 13 with with IN cord-022526-j9kg00qf 1569 14 Vibrio Vibrio NNP cord-022526-j9kg00qf 1569 15 cholerae cholerae NN cord-022526-j9kg00qf 1569 16 , , , cord-022526-j9kg00qf 1569 17 first first RB cord-022526-j9kg00qf 1569 18 described describe VBN cord-022526-j9kg00qf 1569 19 endotoxin endotoxin NN cord-022526-j9kg00qf 1569 20 as as IN cord-022526-j9kg00qf 1569 21 a a DT cord-022526-j9kg00qf 1569 22 toxin toxin NN cord-022526-j9kg00qf 1569 23 " " '' cord-022526-j9kg00qf 1569 24 closely closely RB cord-022526-j9kg00qf 1569 25 attached attach VBN cord-022526-j9kg00qf 1569 26 to to IN cord-022526-j9kg00qf 1569 27 , , , cord-022526-j9kg00qf 1569 28 and and CC cord-022526-j9kg00qf 1569 29 probably probably RB cord-022526-j9kg00qf 1569 30 integral integral JJ cord-022526-j9kg00qf 1569 31 of of IN cord-022526-j9kg00qf 1569 32 , , , cord-022526-j9kg00qf 1569 33 the the DT cord-022526-j9kg00qf 1569 34 bacterial bacterial JJ cord-022526-j9kg00qf 1569 35 body body NN cord-022526-j9kg00qf 1569 36 . . . cord-022526-j9kg00qf 1570 1 " " '' cord-022526-j9kg00qf 1571 1 2 2 LS cord-022526-j9kg00qf 1572 1 He -PRON- PRP cord-022526-j9kg00qf 1572 2 observed observe VBD cord-022526-j9kg00qf 1572 3 this this DT cord-022526-j9kg00qf 1572 4 toxin toxin NN cord-022526-j9kg00qf 1572 5 to to TO cord-022526-j9kg00qf 1572 6 be be VB cord-022526-j9kg00qf 1572 7 distinct distinct JJ cord-022526-j9kg00qf 1572 8 from from IN cord-022526-j9kg00qf 1572 9 the the DT cord-022526-j9kg00qf 1572 10 actively actively RB cord-022526-j9kg00qf 1572 11 secreted secrete VBN cord-022526-j9kg00qf 1572 12 , , , cord-022526-j9kg00qf 1572 13 heat heat NN cord-022526-j9kg00qf 1572 14 - - HYPH cord-022526-j9kg00qf 1572 15 labile labile JJ cord-022526-j9kg00qf 1572 16 , , , cord-022526-j9kg00qf 1572 17 and and CC cord-022526-j9kg00qf 1572 18 proteinaceous proteinaceous JJ cord-022526-j9kg00qf 1572 19 bacterial bacterial JJ cord-022526-j9kg00qf 1572 20 exotoxins exotoxin NNS cord-022526-j9kg00qf 1572 21 . . . cord-022526-j9kg00qf 1573 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1573 2 later later RB cord-022526-j9kg00qf 1573 3 was be VBD cord-022526-j9kg00qf 1573 4 found find VBN cord-022526-j9kg00qf 1573 5 to to TO cord-022526-j9kg00qf 1573 6 be be VB cord-022526-j9kg00qf 1573 7 a a DT cord-022526-j9kg00qf 1573 8 heat heat NN cord-022526-j9kg00qf 1573 9 - - HYPH cord-022526-j9kg00qf 1573 10 stable stable JJ cord-022526-j9kg00qf 1573 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1573 12 structure structure NN cord-022526-j9kg00qf 1573 13 , , , cord-022526-j9kg00qf 1573 14 and and CC cord-022526-j9kg00qf 1573 15 the the DT cord-022526-j9kg00qf 1573 16 terms term NNS cord-022526-j9kg00qf 1573 17 endotoxin endotoxin NN cord-022526-j9kg00qf 1573 18 and and CC cord-022526-j9kg00qf 1573 19 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1573 20 now now RB cord-022526-j9kg00qf 1573 21 are be VBP cord-022526-j9kg00qf 1573 22 used use VBN cord-022526-j9kg00qf 1573 23 interchangeably interchangeably RB cord-022526-j9kg00qf 1573 24 . . . cord-022526-j9kg00qf 1574 1 Lipopolysaccharide Lipopolysaccharide NNP cord-022526-j9kg00qf 1574 2 is be VBZ cord-022526-j9kg00qf 1574 3 a a DT cord-022526-j9kg00qf 1574 4 major major JJ cord-022526-j9kg00qf 1574 5 structural structural JJ cord-022526-j9kg00qf 1574 6 cell cell NN cord-022526-j9kg00qf 1574 7 wall wall NN cord-022526-j9kg00qf 1574 8 component component NN cord-022526-j9kg00qf 1574 9 of of IN cord-022526-j9kg00qf 1574 10 all all DT cord-022526-j9kg00qf 1574 11 gram gram JJ cord-022526-j9kg00qf 1574 12 - - HYPH cord-022526-j9kg00qf 1574 13 negative negative JJ cord-022526-j9kg00qf 1574 14 bacteria bacteria NNS cord-022526-j9kg00qf 1574 15 , , , cord-022526-j9kg00qf 1574 16 including include VBG cord-022526-j9kg00qf 1574 17 noninfectious noninfectious JJ cord-022526-j9kg00qf 1574 18 species specie NNS cord-022526-j9kg00qf 1574 19 ( ( -LRB- cord-022526-j9kg00qf 1574 20 Figure figure NN cord-022526-j9kg00qf 1574 21 13 13 CD cord-022526-j9kg00qf 1574 22 .7 .7 CD cord-022526-j9kg00qf 1574 23 - - HYPH cord-022526-j9kg00qf 1574 24 1 1 CD cord-022526-j9kg00qf 1574 25 ) ) -RRB- cord-022526-j9kg00qf 1574 26 . . . cord-022526-j9kg00qf 1575 1 With with IN cord-022526-j9kg00qf 1575 2 3 3 CD cord-022526-j9kg00qf 1575 3 to to IN cord-022526-j9kg00qf 1575 4 4 4 CD cord-022526-j9kg00qf 1575 5 × × CD cord-022526-j9kg00qf 1575 6 10 10 CD cord-022526-j9kg00qf 1575 7 6 6 CD cord-022526-j9kg00qf 1575 8 molecules molecule NNS cord-022526-j9kg00qf 1575 9 per per IN cord-022526-j9kg00qf 1575 10 cell cell NN cord-022526-j9kg00qf 1575 11 , , , cord-022526-j9kg00qf 1575 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1575 13 makes make VBZ cord-022526-j9kg00qf 1575 14 up up RP cord-022526-j9kg00qf 1575 15 about about RB cord-022526-j9kg00qf 1575 16 75 75 CD cord-022526-j9kg00qf 1575 17 % % NN cord-022526-j9kg00qf 1575 18 of of IN cord-022526-j9kg00qf 1575 19 the the DT cord-022526-j9kg00qf 1575 20 outer outer JJ cord-022526-j9kg00qf 1575 21 layer layer NN cord-022526-j9kg00qf 1575 22 of of IN cord-022526-j9kg00qf 1575 23 the the DT cord-022526-j9kg00qf 1575 24 outer outer JJ cord-022526-j9kg00qf 1575 25 cell cell NN cord-022526-j9kg00qf 1575 26 membrane membrane NN cord-022526-j9kg00qf 1575 27 and and CC cord-022526-j9kg00qf 1575 28 is be VBZ cord-022526-j9kg00qf 1575 29 a a DT cord-022526-j9kg00qf 1575 30 key key JJ cord-022526-j9kg00qf 1575 31 functional functional JJ cord-022526-j9kg00qf 1575 32 molecule molecule NN cord-022526-j9kg00qf 1575 33 for for IN cord-022526-j9kg00qf 1575 34 the the DT cord-022526-j9kg00qf 1575 35 bacterial bacterial JJ cord-022526-j9kg00qf 1575 36 outer outer JJ cord-022526-j9kg00qf 1575 37 membrane membrane NN cord-022526-j9kg00qf 1575 38 , , , cord-022526-j9kg00qf 1575 39 serving serve VBG cord-022526-j9kg00qf 1575 40 as as IN cord-022526-j9kg00qf 1575 41 a a DT cord-022526-j9kg00qf 1575 42 permeability permeability NN cord-022526-j9kg00qf 1575 43 barrier barrier NN cord-022526-j9kg00qf 1575 44 against against IN cord-022526-j9kg00qf 1575 45 external external JJ cord-022526-j9kg00qf 1575 46 noxious noxious JJ cord-022526-j9kg00qf 1575 47 agents agent NNS cord-022526-j9kg00qf 1575 48 . . . cord-022526-j9kg00qf 1576 1 The the DT cord-022526-j9kg00qf 1576 2 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1576 3 molecule molecule NN cord-022526-j9kg00qf 1576 4 consists consist VBZ cord-022526-j9kg00qf 1576 5 of of IN cord-022526-j9kg00qf 1576 6 four four CD cord-022526-j9kg00qf 1576 7 domains domain NNS cord-022526-j9kg00qf 1576 8 , , , cord-022526-j9kg00qf 1576 9 which which WDT cord-022526-j9kg00qf 1576 10 are be VBP cord-022526-j9kg00qf 1576 11 essential essential JJ cord-022526-j9kg00qf 1576 12 for for IN cord-022526-j9kg00qf 1576 13 the the DT cord-022526-j9kg00qf 1576 14 virulence virulence NN cord-022526-j9kg00qf 1576 15 of of IN cord-022526-j9kg00qf 1576 16 gram gram NN cord-022526-j9kg00qf 1576 17 - - HYPH cord-022526-j9kg00qf 1576 18 negative negative JJ cord-022526-j9kg00qf 1576 19 bacteria bacteria NNS cord-022526-j9kg00qf 1576 20 . . . cord-022526-j9kg00qf 1577 1 3 3 CD cord-022526-j9kg00qf 1577 2 Three three CD cord-022526-j9kg00qf 1577 3 of of IN cord-022526-j9kg00qf 1577 4 the the DT cord-022526-j9kg00qf 1577 5 domains domain NNS cord-022526-j9kg00qf 1577 6 ( ( -LRB- cord-022526-j9kg00qf 1577 7 inner inner JJ cord-022526-j9kg00qf 1577 8 core core NN cord-022526-j9kg00qf 1577 9 , , , cord-022526-j9kg00qf 1577 10 outer outer JJ cord-022526-j9kg00qf 1577 11 core core NN cord-022526-j9kg00qf 1577 12 and and CC cord-022526-j9kg00qf 1577 13 O o NN cord-022526-j9kg00qf 1577 14 - - HYPH cord-022526-j9kg00qf 1577 15 specific specific JJ cord-022526-j9kg00qf 1577 16 chain chain NN cord-022526-j9kg00qf 1577 17 ) ) -RRB- cord-022526-j9kg00qf 1577 18 represent represent VB cord-022526-j9kg00qf 1577 19 the the DT cord-022526-j9kg00qf 1577 20 hydrophilic hydrophilic JJ cord-022526-j9kg00qf 1577 21 polysaccharide polysaccharide NN cord-022526-j9kg00qf 1577 22 portion portion NN cord-022526-j9kg00qf 1577 23 of of IN cord-022526-j9kg00qf 1577 24 the the DT cord-022526-j9kg00qf 1577 25 molecule molecule NN cord-022526-j9kg00qf 1577 26 , , , cord-022526-j9kg00qf 1577 27 whereas whereas IN cord-022526-j9kg00qf 1577 28 the the DT cord-022526-j9kg00qf 1577 29 lipid lipid NN cord-022526-j9kg00qf 1577 30 A a DT cord-022526-j9kg00qf 1577 31 portion portion NN cord-022526-j9kg00qf 1577 32 represents represent VBZ cord-022526-j9kg00qf 1577 33 the the DT cord-022526-j9kg00qf 1577 34 hydrophobic hydrophobic JJ cord-022526-j9kg00qf 1577 35 lipid lipid NN cord-022526-j9kg00qf 1577 36 portion portion NN cord-022526-j9kg00qf 1577 37 ( ( -LRB- cord-022526-j9kg00qf 1577 38 Figure figure NN cord-022526-j9kg00qf 1577 39 13 13 CD cord-022526-j9kg00qf 1577 40 .7 .7 CD cord-022526-j9kg00qf 1577 41 - - HYPH cord-022526-j9kg00qf 1577 42 2 2 CD cord-022526-j9kg00qf 1577 43 ) ) -RRB- cord-022526-j9kg00qf 1577 44 . . . cord-022526-j9kg00qf 1578 1 Combined combine VBN cord-022526-j9kg00qf 1578 2 , , , cord-022526-j9kg00qf 1578 3 these these DT cord-022526-j9kg00qf 1578 4 domains domain NNS cord-022526-j9kg00qf 1578 5 confer confer VBP cord-022526-j9kg00qf 1578 6 the the DT cord-022526-j9kg00qf 1578 7 overall overall JJ cord-022526-j9kg00qf 1578 8 amphiphilic amphiphilic JJ cord-022526-j9kg00qf 1578 9 properties property NNS cord-022526-j9kg00qf 1578 10 of of IN cord-022526-j9kg00qf 1578 11 the the DT cord-022526-j9kg00qf 1578 12 molecule molecule NN cord-022526-j9kg00qf 1578 13 that that WDT cord-022526-j9kg00qf 1578 14 lead lead VBP cord-022526-j9kg00qf 1578 15 to to IN cord-022526-j9kg00qf 1578 16 the the DT cord-022526-j9kg00qf 1578 17 formation formation NN cord-022526-j9kg00qf 1578 18 of of IN cord-022526-j9kg00qf 1578 19 micellar micellar JJ cord-022526-j9kg00qf 1578 20 aggregates aggregate NNS cord-022526-j9kg00qf 1578 21 in in IN cord-022526-j9kg00qf 1578 22 aqueous aqueous JJ cord-022526-j9kg00qf 1578 23 solutions solution NNS cord-022526-j9kg00qf 1578 24 . . . cord-022526-j9kg00qf 1579 1 O o UH cord-022526-j9kg00qf 1579 2 - - HYPH cord-022526-j9kg00qf 1579 3 specific specific JJ cord-022526-j9kg00qf 1579 4 chains chain NNS cord-022526-j9kg00qf 1579 5 ( ( -LRB- cord-022526-j9kg00qf 1579 6 also also RB cord-022526-j9kg00qf 1579 7 called call VBN cord-022526-j9kg00qf 1579 8 O o NN cord-022526-j9kg00qf 1579 9 - - HYPH cord-022526-j9kg00qf 1579 10 antigen antigen NN cord-022526-j9kg00qf 1579 11 polysaccharides polysaccharide NNS cord-022526-j9kg00qf 1579 12 or or CC cord-022526-j9kg00qf 1579 13 O o NN cord-022526-j9kg00qf 1579 14 - - HYPH cord-022526-j9kg00qf 1579 15 chains chain NNS cord-022526-j9kg00qf 1579 16 ) ) -RRB- cord-022526-j9kg00qf 1579 17 are be VBP cord-022526-j9kg00qf 1579 18 characteristic characteristic JJ cord-022526-j9kg00qf 1579 19 of of IN cord-022526-j9kg00qf 1579 20 any any DT cord-022526-j9kg00qf 1579 21 given give VBN cord-022526-j9kg00qf 1579 22 type type NN cord-022526-j9kg00qf 1579 23 of of IN cord-022526-j9kg00qf 1579 24 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1579 25 and and CC cord-022526-j9kg00qf 1579 26 show show VB cord-022526-j9kg00qf 1579 27 enormous enormous JJ cord-022526-j9kg00qf 1579 28 structural structural JJ cord-022526-j9kg00qf 1579 29 variability variability NN cord-022526-j9kg00qf 1579 30 between between IN cord-022526-j9kg00qf 1579 31 bacterial bacterial JJ cord-022526-j9kg00qf 1579 32 serotypes serotype NNS cord-022526-j9kg00qf 1579 33 . . . cord-022526-j9kg00qf 1580 1 4 4 LS cord-022526-j9kg00qf 1580 2 O o NN cord-022526-j9kg00qf 1580 3 - - HYPH cord-022526-j9kg00qf 1580 4 chains chain NNS cord-022526-j9kg00qf 1580 5 are be VBP cord-022526-j9kg00qf 1580 6 synthesized synthesize VBN cord-022526-j9kg00qf 1580 7 by by IN cord-022526-j9kg00qf 1580 8 addition addition NN cord-022526-j9kg00qf 1580 9 of of IN cord-022526-j9kg00qf 1580 10 preformed preformed JJ cord-022526-j9kg00qf 1580 11 oligosaccharide oligosaccharide NN cord-022526-j9kg00qf 1580 12 blocks block NNS cord-022526-j9kg00qf 1580 13 to to IN cord-022526-j9kg00qf 1580 14 a a DT cord-022526-j9kg00qf 1580 15 growing grow VBG cord-022526-j9kg00qf 1580 16 polymer polymer NN cord-022526-j9kg00qf 1580 17 chain chain NN cord-022526-j9kg00qf 1580 18 and and CC cord-022526-j9kg00qf 1580 19 therefore therefore RB cord-022526-j9kg00qf 1580 20 have have VBP cord-022526-j9kg00qf 1580 21 a a DT cord-022526-j9kg00qf 1580 22 repetitive repetitive JJ cord-022526-j9kg00qf 1580 23 structure structure NN cord-022526-j9kg00qf 1580 24 . . . cord-022526-j9kg00qf 1581 1 O o UH cord-022526-j9kg00qf 1581 2 - - HYPH cord-022526-j9kg00qf 1581 3 specific specific JJ cord-022526-j9kg00qf 1581 4 chains chain NNS cord-022526-j9kg00qf 1581 5 determine determine VBP cord-022526-j9kg00qf 1581 6 part part NN cord-022526-j9kg00qf 1581 7 of of IN cord-022526-j9kg00qf 1581 8 the the DT cord-022526-j9kg00qf 1581 9 immunospecificity immunospecificity NN cord-022526-j9kg00qf 1581 10 of of IN cord-022526-j9kg00qf 1581 11 bacterial bacterial JJ cord-022526-j9kg00qf 1581 12 cells cell NNS cord-022526-j9kg00qf 1581 13 5 5 CD cord-022526-j9kg00qf 1581 14 and and CC cord-022526-j9kg00qf 1581 15 , , , cord-022526-j9kg00qf 1581 16 on on IN cord-022526-j9kg00qf 1581 17 interaction interaction NN cord-022526-j9kg00qf 1581 18 with with IN cord-022526-j9kg00qf 1581 19 the the DT cord-022526-j9kg00qf 1581 20 host host NN cord-022526-j9kg00qf 1581 21 immune immune JJ cord-022526-j9kg00qf 1581 22 system system NN cord-022526-j9kg00qf 1581 23 , , , cord-022526-j9kg00qf 1581 24 serve serve VBP cord-022526-j9kg00qf 1581 25 as as IN cord-022526-j9kg00qf 1581 26 antigens antigen NNS cord-022526-j9kg00qf 1581 27 for for IN cord-022526-j9kg00qf 1581 28 the the DT cord-022526-j9kg00qf 1581 29 production production NN cord-022526-j9kg00qf 1581 30 of of IN cord-022526-j9kg00qf 1581 31 species species NN cord-022526-j9kg00qf 1581 32 - - HYPH cord-022526-j9kg00qf 1581 33 specific specific JJ cord-022526-j9kg00qf 1581 34 antibodies antibody NNS cord-022526-j9kg00qf 1581 35 . . . cord-022526-j9kg00qf 1582 1 6 6 CD cord-022526-j9kg00qf 1582 2 O o NN cord-022526-j9kg00qf 1582 3 - - HYPH cord-022526-j9kg00qf 1582 4 specific specific JJ cord-022526-j9kg00qf 1582 5 chains chain NNS cord-022526-j9kg00qf 1582 6 are be VBP cord-022526-j9kg00qf 1582 7 further further RB cord-022526-j9kg00qf 1582 8 responsible responsible JJ cord-022526-j9kg00qf 1582 9 for for IN cord-022526-j9kg00qf 1582 10 the the DT cord-022526-j9kg00qf 1582 11 smooth smooth JJ cord-022526-j9kg00qf 1582 12 appearance appearance NN cord-022526-j9kg00qf 1582 13 of of IN cord-022526-j9kg00qf 1582 14 gram gram NN cord-022526-j9kg00qf 1582 15 - - HYPH cord-022526-j9kg00qf 1582 16 negative negative JJ cord-022526-j9kg00qf 1582 17 bacterial bacterial JJ cord-022526-j9kg00qf 1582 18 colonies colony NNS cord-022526-j9kg00qf 1582 19 on on IN cord-022526-j9kg00qf 1582 20 culture culture NN cord-022526-j9kg00qf 1582 21 plates plate NNS cord-022526-j9kg00qf 1582 22 , , , cord-022526-j9kg00qf 1582 23 3 3 CD cord-022526-j9kg00qf 1582 24 and and CC cord-022526-j9kg00qf 1582 25 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1582 26 molecules molecule NNS cord-022526-j9kg00qf 1582 27 containing contain VBG cord-022526-j9kg00qf 1582 28 an an DT cord-022526-j9kg00qf 1582 29 O o NN cord-022526-j9kg00qf 1582 30 - - HYPH cord-022526-j9kg00qf 1582 31 chain chain NN cord-022526-j9kg00qf 1582 32 are be VBP cord-022526-j9kg00qf 1582 33 termed term VBN cord-022526-j9kg00qf 1582 34 smooth smooth JJ cord-022526-j9kg00qf 1582 35 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1582 36 . . . cord-022526-j9kg00qf 1583 1 The the DT cord-022526-j9kg00qf 1583 2 inner inner JJ cord-022526-j9kg00qf 1583 3 ( ( -LRB- cord-022526-j9kg00qf 1583 4 lipid lipid NN cord-022526-j9kg00qf 1583 5 A a NN cord-022526-j9kg00qf 1583 6 - - HYPH cord-022526-j9kg00qf 1583 7 proximal proximal JJ cord-022526-j9kg00qf 1583 8 ) ) -RRB- cord-022526-j9kg00qf 1583 9 and and CC cord-022526-j9kg00qf 1583 10 outer outer JJ cord-022526-j9kg00qf 1583 11 ( ( -LRB- cord-022526-j9kg00qf 1583 12 O o NN cord-022526-j9kg00qf 1583 13 - - HYPH cord-022526-j9kg00qf 1583 14 chainproximal chainproximal NN cord-022526-j9kg00qf 1583 15 ) ) -RRB- cord-022526-j9kg00qf 1584 1 core core JJ cord-022526-j9kg00qf 1584 2 oligosaccharide oligosaccharide NN cord-022526-j9kg00qf 1584 3 portion portion NN cord-022526-j9kg00qf 1584 4 is be VBZ cord-022526-j9kg00qf 1584 5 more more RBR cord-022526-j9kg00qf 1584 6 conserved conserve VBN cord-022526-j9kg00qf 1584 7 between between IN cord-022526-j9kg00qf 1584 8 different different JJ cord-022526-j9kg00qf 1584 9 strains strain NNS cord-022526-j9kg00qf 1584 10 of of IN cord-022526-j9kg00qf 1584 11 gram gram NN cord-022526-j9kg00qf 1584 12 - - HYPH cord-022526-j9kg00qf 1584 13 negative negative JJ cord-022526-j9kg00qf 1584 14 bacteria bacteria NNS cord-022526-j9kg00qf 1584 15 than than IN cord-022526-j9kg00qf 1584 16 the the DT cord-022526-j9kg00qf 1584 17 O o NN cord-022526-j9kg00qf 1584 18 - - HYPH cord-022526-j9kg00qf 1584 19 specific specific JJ cord-022526-j9kg00qf 1584 20 chain chain NN cord-022526-j9kg00qf 1584 21 . . . cord-022526-j9kg00qf 1585 1 4 4 LS cord-022526-j9kg00qf 1586 1 The the DT cord-022526-j9kg00qf 1586 2 core core NN cord-022526-j9kg00qf 1586 3 of of IN cord-022526-j9kg00qf 1586 4 all all DT cord-022526-j9kg00qf 1586 5 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1586 6 molecules molecule NNS cord-022526-j9kg00qf 1586 7 contains contain VBZ cord-022526-j9kg00qf 1586 8 the the DT cord-022526-j9kg00qf 1586 9 unusual unusual JJ cord-022526-j9kg00qf 1586 10 sugar sugar NN cord-022526-j9kg00qf 1586 11 KDO KDO NNP cord-022526-j9kg00qf 1586 12 ( ( -LRB- cord-022526-j9kg00qf 1586 13 3-deoxy 3-deoxy CD cord-022526-j9kg00qf 1586 14 - - HYPH cord-022526-j9kg00qf 1586 15 Dmanno Dmanno NNP cord-022526-j9kg00qf 1586 16 - - HYPH cord-022526-j9kg00qf 1586 17 oct-2-ulopyranosonic oct-2-ulopyranosonic CD cord-022526-j9kg00qf 1586 18 acid acid NN cord-022526-j9kg00qf 1586 19 ) ) -RRB- cord-022526-j9kg00qf 1586 20 , , , cord-022526-j9kg00qf 1586 21 which which WDT cord-022526-j9kg00qf 1586 22 links link VBZ cord-022526-j9kg00qf 1586 23 the the DT cord-022526-j9kg00qf 1586 24 core core NN cord-022526-j9kg00qf 1586 25 region region NN cord-022526-j9kg00qf 1586 26 to to IN cord-022526-j9kg00qf 1586 27 the the DT cord-022526-j9kg00qf 1586 28 lipid lipid NN cord-022526-j9kg00qf 1586 29 A a DT cord-022526-j9kg00qf 1586 30 molecule molecule NN cord-022526-j9kg00qf 1586 31 . . . cord-022526-j9kg00qf 1587 1 Synthesis synthesis NN cord-022526-j9kg00qf 1587 2 of of IN cord-022526-j9kg00qf 1587 3 a a DT cord-022526-j9kg00qf 1587 4 minimal minimal JJ cord-022526-j9kg00qf 1587 5 core core NN cord-022526-j9kg00qf 1587 6 is be VBZ cord-022526-j9kg00qf 1587 7 essential essential JJ cord-022526-j9kg00qf 1587 8 for for IN cord-022526-j9kg00qf 1587 9 the the DT cord-022526-j9kg00qf 1587 10 survival survival NN cord-022526-j9kg00qf 1587 11 of of IN cord-022526-j9kg00qf 1587 12 bacteria bacteria NNS cord-022526-j9kg00qf 1587 13 , , , cord-022526-j9kg00qf 1587 14 7 7 CD cord-022526-j9kg00qf 1587 15 and and CC cord-022526-j9kg00qf 1587 16 the the DT cord-022526-j9kg00qf 1587 17 smallest small JJS cord-022526-j9kg00qf 1587 18 naturally naturally RB cord-022526-j9kg00qf 1587 19 occurring occur VBG cord-022526-j9kg00qf 1587 20 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1587 21 structure structure NN cord-022526-j9kg00qf 1587 22 consists consist VBZ cord-022526-j9kg00qf 1587 23 of of IN cord-022526-j9kg00qf 1587 24 lipid lipid NN cord-022526-j9kg00qf 1587 25 A A NNP cord-022526-j9kg00qf 1587 26 and and CC cord-022526-j9kg00qf 1587 27 KDO KDO NNP cord-022526-j9kg00qf 1587 28 . . . cord-022526-j9kg00qf 1588 1 8 8 CD cord-022526-j9kg00qf 1589 1 In in IN cord-022526-j9kg00qf 1589 2 contrast contrast NN cord-022526-j9kg00qf 1589 3 to to IN cord-022526-j9kg00qf 1589 4 the the DT cord-022526-j9kg00qf 1589 5 S s NN cord-022526-j9kg00qf 1589 6 - - HYPH cord-022526-j9kg00qf 1589 7 form form NN cord-022526-j9kg00qf 1589 8 colonies colony NNS cord-022526-j9kg00qf 1589 9 , , , cord-022526-j9kg00qf 1589 10 colonies colony NNS cord-022526-j9kg00qf 1589 11 of of IN cord-022526-j9kg00qf 1589 12 gram gram NN cord-022526-j9kg00qf 1589 13 - - HYPH cord-022526-j9kg00qf 1589 14 negative negative JJ cord-022526-j9kg00qf 1589 15 bacteria bacteria NNS cord-022526-j9kg00qf 1589 16 with with IN cord-022526-j9kg00qf 1589 17 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1589 18 molecules molecule NNS cord-022526-j9kg00qf 1589 19 that that WDT cord-022526-j9kg00qf 1589 20 lack lack VBP cord-022526-j9kg00qf 1589 21 the the DT cord-022526-j9kg00qf 1589 22 O o NN cord-022526-j9kg00qf 1589 23 - - HYPH cord-022526-j9kg00qf 1589 24 specific specific JJ cord-022526-j9kg00qf 1589 25 chain chain NN cord-022526-j9kg00qf 1589 26 but but CC cord-022526-j9kg00qf 1589 27 contain contain VBP cord-022526-j9kg00qf 1589 28 a a DT cord-022526-j9kg00qf 1589 29 core core NN cord-022526-j9kg00qf 1589 30 region region NN cord-022526-j9kg00qf 1589 31 show show VBP cord-022526-j9kg00qf 1589 32 a a DT cord-022526-j9kg00qf 1589 33 rough rough JJ cord-022526-j9kg00qf 1589 34 appearance appearance NN cord-022526-j9kg00qf 1589 35 on on IN cord-022526-j9kg00qf 1589 36 culture culture NN cord-022526-j9kg00qf 1589 37 plates plate NNS cord-022526-j9kg00qf 1589 38 . . . cord-022526-j9kg00qf 1590 1 Rough rough JJ cord-022526-j9kg00qf 1590 2 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1590 3 molecules molecule NNS cord-022526-j9kg00qf 1590 4 are be VBP cord-022526-j9kg00qf 1590 5 denoted denote VBN cord-022526-j9kg00qf 1590 6 further further RB cord-022526-j9kg00qf 1590 7 as as IN cord-022526-j9kg00qf 1590 8 Ra Ra NNP cord-022526-j9kg00qf 1590 9 , , , cord-022526-j9kg00qf 1590 10 Rb Rb NNP cord-022526-j9kg00qf 1590 11 , , , cord-022526-j9kg00qf 1590 12 etc etc FW cord-022526-j9kg00qf 1590 13 . . . cord-022526-j9kg00qf 1591 1 to to TO cord-022526-j9kg00qf 1591 2 indicate indicate VB cord-022526-j9kg00qf 1591 3 the the DT cord-022526-j9kg00qf 1591 4 length length NN cord-022526-j9kg00qf 1591 5 of of IN cord-022526-j9kg00qf 1591 6 the the DT cord-022526-j9kg00qf 1591 7 core core NN cord-022526-j9kg00qf 1591 8 region region NN cord-022526-j9kg00qf 1591 9 . . . cord-022526-j9kg00qf 1592 1 In in IN cord-022526-j9kg00qf 1592 2 Re re NN cord-022526-j9kg00qf 1592 3 - - NN cord-022526-j9kg00qf 1592 4 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1592 5 ( ( -LRB- cord-022526-j9kg00qf 1592 6 also also RB cord-022526-j9kg00qf 1592 7 called call VBN cord-022526-j9kg00qf 1592 8 deep deep JJ cord-022526-j9kg00qf 1592 9 rough rough JJ cord-022526-j9kg00qf 1592 10 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1592 11 ) ) -RRB- cord-022526-j9kg00qf 1592 12 , , , cord-022526-j9kg00qf 1592 13 the the DT cord-022526-j9kg00qf 1592 14 core core NN cord-022526-j9kg00qf 1592 15 region region NN cord-022526-j9kg00qf 1592 16 is be VBZ cord-022526-j9kg00qf 1592 17 reduced reduce VBN cord-022526-j9kg00qf 1592 18 to to IN cord-022526-j9kg00qf 1592 19 a a DT cord-022526-j9kg00qf 1592 20 KDO KDO NNP cord-022526-j9kg00qf 1592 21 residue residue NN cord-022526-j9kg00qf 1592 22 . . . cord-022526-j9kg00qf 1593 1 Remutants remutant NNS cord-022526-j9kg00qf 1593 2 often often RB cord-022526-j9kg00qf 1593 3 are be VBP cord-022526-j9kg00qf 1593 4 used use VBN cord-022526-j9kg00qf 1593 5 to to TO cord-022526-j9kg00qf 1593 6 raise raise VB cord-022526-j9kg00qf 1593 7 antibodies antibody NNS cord-022526-j9kg00qf 1593 8 against against IN cord-022526-j9kg00qf 1593 9 the the DT cord-022526-j9kg00qf 1593 10 core core NN cord-022526-j9kg00qf 1593 11 region region NN cord-022526-j9kg00qf 1593 12 in in IN cord-022526-j9kg00qf 1593 13 an an DT cord-022526-j9kg00qf 1593 14 attempt attempt NN cord-022526-j9kg00qf 1593 15 to to TO cord-022526-j9kg00qf 1593 16 provide provide VB cord-022526-j9kg00qf 1593 17 cross cross NN cord-022526-j9kg00qf 1593 18 - - NN cord-022526-j9kg00qf 1593 19 protection protection NN cord-022526-j9kg00qf 1593 20 against against IN cord-022526-j9kg00qf 1593 21 a a DT cord-022526-j9kg00qf 1593 22 variety variety NN cord-022526-j9kg00qf 1593 23 of of IN cord-022526-j9kg00qf 1593 24 bacterial bacterial JJ cord-022526-j9kg00qf 1593 25 species specie NNS cord-022526-j9kg00qf 1593 26 . . . cord-022526-j9kg00qf 1594 1 The the DT cord-022526-j9kg00qf 1594 2 lipid lipid NN cord-022526-j9kg00qf 1594 3 A a DT cord-022526-j9kg00qf 1594 4 portion portion NN cord-022526-j9kg00qf 1594 5 serves serve VBZ cord-022526-j9kg00qf 1594 6 to to TO cord-022526-j9kg00qf 1594 7 anchor anchor VB cord-022526-j9kg00qf 1594 8 the the DT cord-022526-j9kg00qf 1594 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1594 10 molecule molecule NN cord-022526-j9kg00qf 1594 11 in in IN cord-022526-j9kg00qf 1594 12 the the DT cord-022526-j9kg00qf 1594 13 bacterial bacterial JJ cord-022526-j9kg00qf 1594 14 outer outer JJ cord-022526-j9kg00qf 1594 15 membrane membrane NN cord-022526-j9kg00qf 1594 16 and and CC cord-022526-j9kg00qf 1594 17 has have VBZ cord-022526-j9kg00qf 1594 18 been be VBN cord-022526-j9kg00qf 1594 19 identified identify VBN cord-022526-j9kg00qf 1594 20 as as IN cord-022526-j9kg00qf 1594 21 the the DT cord-022526-j9kg00qf 1594 22 toxic toxic JJ cord-022526-j9kg00qf 1594 23 principle principle NN cord-022526-j9kg00qf 1594 24 of of IN cord-022526-j9kg00qf 1594 25 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1594 26 , , , cord-022526-j9kg00qf 1594 27 9 9 CD cord-022526-j9kg00qf 1594 28 and and CC cord-022526-j9kg00qf 1594 29 its -PRON- PRP$ cord-022526-j9kg00qf 1594 30 structure structure NN cord-022526-j9kg00qf 1594 31 is be VBZ cord-022526-j9kg00qf 1594 32 highly highly RB cord-022526-j9kg00qf 1594 33 conserved conserve VBN cord-022526-j9kg00qf 1594 34 among among IN cord-022526-j9kg00qf 1594 35 gramnegative gramnegative JJ cord-022526-j9kg00qf 1594 36 bacteria bacteria NNS cord-022526-j9kg00qf 1594 37 . . . cord-022526-j9kg00qf 1595 1 The the DT cord-022526-j9kg00qf 1595 2 common common JJ cord-022526-j9kg00qf 1595 3 structure structure NN cord-022526-j9kg00qf 1595 4 shared share VBN cord-022526-j9kg00qf 1595 5 by by IN cord-022526-j9kg00qf 1595 6 lipid lipid NN cord-022526-j9kg00qf 1595 7 A a DT cord-022526-j9kg00qf 1595 8 molecules molecule NNS cord-022526-j9kg00qf 1595 9 is be VBZ cord-022526-j9kg00qf 1595 10 a a DT cord-022526-j9kg00qf 1595 11 1,4'-bisphosphorylated 1,4'-bisphosphorylated JJ cord-022526-j9kg00qf 1595 12 β1,6-linked β1,6-linked NNP cord-022526-j9kg00qf 1595 13 D d NN cord-022526-j9kg00qf 1595 14 - - HYPH cord-022526-j9kg00qf 1595 15 glucosamine glucosamine NN cord-022526-j9kg00qf 1595 16 disaccharide disaccharide NN cord-022526-j9kg00qf 1595 17 backbone backbone NN cord-022526-j9kg00qf 1595 18 ( ( -LRB- cord-022526-j9kg00qf 1595 19 lipid lipid NN cord-022526-j9kg00qf 1595 20 A a DT cord-022526-j9kg00qf 1595 21 backbone backbone NN cord-022526-j9kg00qf 1595 22 ) ) -RRB- cord-022526-j9kg00qf 1595 23 , , , cord-022526-j9kg00qf 1595 24 which which WDT cord-022526-j9kg00qf 1595 25 is be VBZ cord-022526-j9kg00qf 1595 26 acylated acylate VBN cord-022526-j9kg00qf 1595 27 by by IN cord-022526-j9kg00qf 1595 28 up up IN cord-022526-j9kg00qf 1595 29 to to TO cord-022526-j9kg00qf 1595 30 six six CD cord-022526-j9kg00qf 1595 31 fatty fatty JJ cord-022526-j9kg00qf 1595 32 acids acid NNS cord-022526-j9kg00qf 1595 33 . . . cord-022526-j9kg00qf 1596 1 4 4 CD cord-022526-j9kg00qf 1596 2 Figure figure NN cord-022526-j9kg00qf 1596 3 13 13 CD cord-022526-j9kg00qf 1596 4 .7 .7 CD cord-022526-j9kg00qf 1596 5 - - HYPH cord-022526-j9kg00qf 1596 6 3 3 CD cord-022526-j9kg00qf 1596 7 shows show VBZ cord-022526-j9kg00qf 1596 8 the the DT cord-022526-j9kg00qf 1596 9 acylation acylation NN cord-022526-j9kg00qf 1596 10 pattern pattern NN cord-022526-j9kg00qf 1596 11 for for IN cord-022526-j9kg00qf 1596 12 Escherichia Escherichia NNP cord-022526-j9kg00qf 1596 13 coli coli NNS cord-022526-j9kg00qf 1596 14 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1596 15 . . . cord-022526-j9kg00qf 1597 1 Variation variation NN cord-022526-j9kg00qf 1597 2 in in IN cord-022526-j9kg00qf 1597 3 the the DT cord-022526-j9kg00qf 1597 4 lipid lipid NN cord-022526-j9kg00qf 1598 1 A a DT cord-022526-j9kg00qf 1598 2 structure structure NN cord-022526-j9kg00qf 1598 3 between between IN cord-022526-j9kg00qf 1598 4 gramnegative gramnegative NNP cord-022526-j9kg00qf 1598 5 bacteria bacteria NNS cord-022526-j9kg00qf 1598 6 affects affect VBZ cord-022526-j9kg00qf 1598 7 the the DT cord-022526-j9kg00qf 1598 8 number number NN cord-022526-j9kg00qf 1598 9 , , , cord-022526-j9kg00qf 1598 10 length length NN cord-022526-j9kg00qf 1598 11 , , , cord-022526-j9kg00qf 1598 12 and and CC cord-022526-j9kg00qf 1598 13 position position NN cord-022526-j9kg00qf 1598 14 of of IN cord-022526-j9kg00qf 1598 15 fatty fatty JJ cord-022526-j9kg00qf 1598 16 acids acid NNS cord-022526-j9kg00qf 1598 17 and and CC cord-022526-j9kg00qf 1598 18 the the DT cord-022526-j9kg00qf 1598 19 backbone backbone NN cord-022526-j9kg00qf 1598 20 structure structure NN cord-022526-j9kg00qf 1598 21 and and CC cord-022526-j9kg00qf 1598 22 the the DT cord-022526-j9kg00qf 1598 23 substitution substitution NN cord-022526-j9kg00qf 1598 24 of of IN cord-022526-j9kg00qf 1598 25 phosphate phosphate NN cord-022526-j9kg00qf 1598 26 by by IN cord-022526-j9kg00qf 1598 27 other other JJ cord-022526-j9kg00qf 1598 28 polar polar JJ cord-022526-j9kg00qf 1598 29 groups group NNS cord-022526-j9kg00qf 1598 30 . . . cord-022526-j9kg00qf 1599 1 6 6 CD cord-022526-j9kg00qf 1600 1 According accord VBG cord-022526-j9kg00qf 1600 2 to to IN cord-022526-j9kg00qf 1600 3 its -PRON- PRP$ cord-022526-j9kg00qf 1600 4 nature nature NN cord-022526-j9kg00qf 1600 5 as as IN cord-022526-j9kg00qf 1600 6 a a DT cord-022526-j9kg00qf 1600 7 structural structural JJ cord-022526-j9kg00qf 1600 8 cell cell NN cord-022526-j9kg00qf 1600 9 wall wall NN cord-022526-j9kg00qf 1600 10 component component NN cord-022526-j9kg00qf 1600 11 , , , cord-022526-j9kg00qf 1600 12 the the DT cord-022526-j9kg00qf 1600 13 presence presence NN cord-022526-j9kg00qf 1600 14 of of IN cord-022526-j9kg00qf 1600 15 endotoxin endotoxin NN cord-022526-j9kg00qf 1600 16 implies imply VBZ cord-022526-j9kg00qf 1600 17 the the DT cord-022526-j9kg00qf 1600 18 presence presence NN cord-022526-j9kg00qf 1600 19 of of IN cord-022526-j9kg00qf 1600 20 gram gram NN cord-022526-j9kg00qf 1600 21 - - HYPH cord-022526-j9kg00qf 1600 22 negative negative JJ cord-022526-j9kg00qf 1600 23 bacteria bacteria NNS cord-022526-j9kg00qf 1600 24 as as IN cord-022526-j9kg00qf 1600 25 a a DT cord-022526-j9kg00qf 1600 26 source source NN cord-022526-j9kg00qf 1600 27 . . . cord-022526-j9kg00qf 1601 1 Depending depend VBG cord-022526-j9kg00qf 1601 2 on on IN cord-022526-j9kg00qf 1601 3 the the DT cord-022526-j9kg00qf 1601 4 nature nature NN cord-022526-j9kg00qf 1601 5 of of IN cord-022526-j9kg00qf 1601 6 the the DT cord-022526-j9kg00qf 1601 7 underlying underlie VBG cord-022526-j9kg00qf 1601 8 disease disease NN cord-022526-j9kg00qf 1601 9 , , , cord-022526-j9kg00qf 1601 10 these these DT cord-022526-j9kg00qf 1601 11 bacteria bacteria NNS cord-022526-j9kg00qf 1601 12 may may MD cord-022526-j9kg00qf 1601 13 circulate circulate VB cord-022526-j9kg00qf 1601 14 in in IN cord-022526-j9kg00qf 1601 15 the the DT cord-022526-j9kg00qf 1601 16 bloodstream bloodstream NN cord-022526-j9kg00qf 1601 17 in in IN cord-022526-j9kg00qf 1601 18 their -PRON- PRP$ cord-022526-j9kg00qf 1601 19 intact intact JJ cord-022526-j9kg00qf 1601 20 form form NN cord-022526-j9kg00qf 1601 21 ( ( -LRB- cord-022526-j9kg00qf 1601 22 i.e. i.e. FW cord-022526-j9kg00qf 1601 23 , , , cord-022526-j9kg00qf 1601 24 bacteremia bacteremia NN cord-022526-j9kg00qf 1601 25 ) ) -RRB- cord-022526-j9kg00qf 1601 26 , , , cord-022526-j9kg00qf 1601 27 may may MD cord-022526-j9kg00qf 1601 28 be be VB cord-022526-j9kg00qf 1601 29 confined confine VBN cord-022526-j9kg00qf 1601 30 to to IN cord-022526-j9kg00qf 1601 31 a a DT cord-022526-j9kg00qf 1601 32 localized localized JJ cord-022526-j9kg00qf 1601 33 infectious infectious JJ cord-022526-j9kg00qf 1601 34 process process NN cord-022526-j9kg00qf 1601 35 , , , cord-022526-j9kg00qf 1601 36 or or CC cord-022526-j9kg00qf 1601 37 may may MD cord-022526-j9kg00qf 1601 38 be be VB cord-022526-j9kg00qf 1601 39 part part NN cord-022526-j9kg00qf 1601 40 of of IN cord-022526-j9kg00qf 1601 41 the the DT cord-022526-j9kg00qf 1601 42 endogenous endogenous JJ cord-022526-j9kg00qf 1601 43 bacterial bacterial JJ cord-022526-j9kg00qf 1601 44 flora flora NNS cord-022526-j9kg00qf 1601 45 colonizing colonize VBG cord-022526-j9kg00qf 1601 46 the the DT cord-022526-j9kg00qf 1601 47 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1601 48 tract tract NN cord-022526-j9kg00qf 1601 49 . . . cord-022526-j9kg00qf 1602 1 In in IN cord-022526-j9kg00qf 1602 2 any any DT cord-022526-j9kg00qf 1602 3 of of IN cord-022526-j9kg00qf 1602 4 these these DT cord-022526-j9kg00qf 1602 5 scenarios scenario NNS cord-022526-j9kg00qf 1602 6 , , , cord-022526-j9kg00qf 1602 7 endotoxin endotoxin NN cord-022526-j9kg00qf 1602 8 molecules molecule NNS cord-022526-j9kg00qf 1602 9 are be VBP cord-022526-j9kg00qf 1602 10 released release VBN cord-022526-j9kg00qf 1602 11 as as IN cord-022526-j9kg00qf 1602 12 a a DT cord-022526-j9kg00qf 1602 13 by by IN cord-022526-j9kg00qf 1602 14 - - HYPH cord-022526-j9kg00qf 1602 15 product product NN cord-022526-j9kg00qf 1602 16 of of IN cord-022526-j9kg00qf 1602 17 bacterial bacterial JJ cord-022526-j9kg00qf 1602 18 growth growth NN cord-022526-j9kg00qf 1602 19 and and CC cord-022526-j9kg00qf 1602 20 in in IN cord-022526-j9kg00qf 1602 21 large large JJ cord-022526-j9kg00qf 1602 22 numbers number NNS cord-022526-j9kg00qf 1602 23 on on IN cord-022526-j9kg00qf 1602 24 bacterial bacterial JJ cord-022526-j9kg00qf 1602 25 cell cell NN cord-022526-j9kg00qf 1602 26 death death NN cord-022526-j9kg00qf 1602 27 . . . cord-022526-j9kg00qf 1603 1 10 10 CD cord-022526-j9kg00qf 1603 2 Common common JJ cord-022526-j9kg00qf 1603 3 infectious infectious JJ cord-022526-j9kg00qf 1603 4 conditions condition NNS cord-022526-j9kg00qf 1603 5 associated associate VBN cord-022526-j9kg00qf 1603 6 with with IN cord-022526-j9kg00qf 1603 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1603 8 in in IN cord-022526-j9kg00qf 1603 9 horses horse NNS cord-022526-j9kg00qf 1603 10 include include VBP cord-022526-j9kg00qf 1603 11 neonatal neonatal JJ cord-022526-j9kg00qf 1603 12 gram gram JJ cord-022526-j9kg00qf 1603 13 - - HYPH cord-022526-j9kg00qf 1603 14 negative negative JJ cord-022526-j9kg00qf 1603 15 sepsis sepsis NN cord-022526-j9kg00qf 1603 16 , , , cord-022526-j9kg00qf 1603 17 bacterial bacterial JJ cord-022526-j9kg00qf 1603 18 pneumonia pneumonia NN cord-022526-j9kg00qf 1603 19 and and CC cord-022526-j9kg00qf 1603 20 pleuropneumonia pleuropneumonia NNP cord-022526-j9kg00qf 1603 21 , , , cord-022526-j9kg00qf 1603 22 endometritis endometritis NNP cord-022526-j9kg00qf 1603 23 , , , cord-022526-j9kg00qf 1603 24 peritonitis peritonitis NN cord-022526-j9kg00qf 1603 25 , , , cord-022526-j9kg00qf 1603 26 and and CC cord-022526-j9kg00qf 1603 27 infectious infectious JJ cord-022526-j9kg00qf 1603 28 colitis colitis NN cord-022526-j9kg00qf 1603 29 with with IN cord-022526-j9kg00qf 1603 30 bacteria bacteria NNS cord-022526-j9kg00qf 1603 31 such such JJ cord-022526-j9kg00qf 1603 32 as as IN cord-022526-j9kg00qf 1603 33 Salmonella Salmonella NNP cord-022526-j9kg00qf 1603 34 spp spp NNP cord-022526-j9kg00qf 1603 35 . . . cord-022526-j9kg00qf 1604 1 , , , cord-022526-j9kg00qf 1604 2 that that WDT cord-022526-j9kg00qf 1604 3 are be VBP cord-022526-j9kg00qf 1604 4 not not RB cord-022526-j9kg00qf 1604 5 part part NN cord-022526-j9kg00qf 1604 6 of of IN cord-022526-j9kg00qf 1604 7 the the DT cord-022526-j9kg00qf 1604 8 normal normal JJ cord-022526-j9kg00qf 1604 9 intestinal intestinal JJ cord-022526-j9kg00qf 1604 10 flora flora NNS cord-022526-j9kg00qf 1604 11 . . . cord-022526-j9kg00qf 1605 1 In in IN cord-022526-j9kg00qf 1605 2 one one CD cord-022526-j9kg00qf 1605 3 study study NN cord-022526-j9kg00qf 1605 4 , , , cord-022526-j9kg00qf 1605 5 for for IN cord-022526-j9kg00qf 1605 6 example example NN cord-022526-j9kg00qf 1605 7 , , , cord-022526-j9kg00qf 1605 8 endotoxin endotoxin NN cord-022526-j9kg00qf 1605 9 was be VBD cord-022526-j9kg00qf 1605 10 detectable detectable JJ cord-022526-j9kg00qf 1605 11 in in IN cord-022526-j9kg00qf 1605 12 plasma plasma NN cord-022526-j9kg00qf 1605 13 of of IN cord-022526-j9kg00qf 1605 14 50 50 CD cord-022526-j9kg00qf 1605 15 % % NN cord-022526-j9kg00qf 1605 16 of of IN cord-022526-j9kg00qf 1605 17 foals foal NNS cord-022526-j9kg00qf 1605 18 evaluated evaluate VBN cord-022526-j9kg00qf 1605 19 for for IN cord-022526-j9kg00qf 1605 20 presumed presumed JJ cord-022526-j9kg00qf 1605 21 sepsis sepsis NN cord-022526-j9kg00qf 1605 22 . . . cord-022526-j9kg00qf 1606 1 11 11 CD cord-022526-j9kg00qf 1607 1 The the DT cord-022526-j9kg00qf 1607 2 term term NN cord-022526-j9kg00qf 1607 3 translocation translocation NN cord-022526-j9kg00qf 1607 4 describes describe VBZ cord-022526-j9kg00qf 1607 5 entry entry NN cord-022526-j9kg00qf 1607 6 of of IN cord-022526-j9kg00qf 1607 7 endogenous endogenous JJ cord-022526-j9kg00qf 1607 8 bacteria bacteria NNS cord-022526-j9kg00qf 1607 9 and and CC cord-022526-j9kg00qf 1607 10 bacterial bacterial JJ cord-022526-j9kg00qf 1607 11 products product NNS cord-022526-j9kg00qf 1607 12 from from IN cord-022526-j9kg00qf 1607 13 the the DT cord-022526-j9kg00qf 1607 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1607 15 tract tract NN cord-022526-j9kg00qf 1607 16 into into IN cord-022526-j9kg00qf 1607 17 tissues tissue NNS cord-022526-j9kg00qf 1607 18 and and CC cord-022526-j9kg00qf 1607 19 the the DT cord-022526-j9kg00qf 1607 20 systemic systemic JJ cord-022526-j9kg00qf 1607 21 circulation circulation NN cord-022526-j9kg00qf 1607 22 . . . cord-022526-j9kg00qf 1608 1 12 12 CD cord-022526-j9kg00qf 1609 1 The the DT cord-022526-j9kg00qf 1609 2 natural natural JJ cord-022526-j9kg00qf 1609 3 intestinal intestinal JJ cord-022526-j9kg00qf 1609 4 flora flora NNS cord-022526-j9kg00qf 1609 5 of of IN cord-022526-j9kg00qf 1609 6 horses horse NNS cord-022526-j9kg00qf 1609 7 consists consist VBZ cord-022526-j9kg00qf 1609 8 mainly mainly RB cord-022526-j9kg00qf 1609 9 of of IN cord-022526-j9kg00qf 1609 10 gramnegative gramnegative NN cord-022526-j9kg00qf 1609 11 , , , cord-022526-j9kg00qf 1609 12 anaerobic anaerobic JJ cord-022526-j9kg00qf 1609 13 bacteria bacteria NNS cord-022526-j9kg00qf 1609 14 , , , cord-022526-j9kg00qf 1609 15 and and CC cord-022526-j9kg00qf 1609 16 thus thus RB cord-022526-j9kg00qf 1609 17 large large JJ cord-022526-j9kg00qf 1609 18 amounts amount NNS cord-022526-j9kg00qf 1609 19 of of IN cord-022526-j9kg00qf 1609 20 endotoxin endotoxin NN cord-022526-j9kg00qf 1609 21 normally normally RB cord-022526-j9kg00qf 1609 22 exist exist VBP cord-022526-j9kg00qf 1609 23 in in IN cord-022526-j9kg00qf 1609 24 the the DT cord-022526-j9kg00qf 1609 25 lumen lumen NN cord-022526-j9kg00qf 1609 26 of of IN cord-022526-j9kg00qf 1609 27 the the DT cord-022526-j9kg00qf 1609 28 equine equine JJ cord-022526-j9kg00qf 1609 29 intestinal intestinal JJ cord-022526-j9kg00qf 1609 30 tract tract NN cord-022526-j9kg00qf 1609 31 . . . cord-022526-j9kg00qf 1610 1 13 13 CD cord-022526-j9kg00qf 1611 1 Even even RB cord-022526-j9kg00qf 1611 2 in in IN cord-022526-j9kg00qf 1611 3 health health NN cord-022526-j9kg00qf 1611 4 , , , cord-022526-j9kg00qf 1611 5 small small JJ cord-022526-j9kg00qf 1611 6 amounts amount NNS cord-022526-j9kg00qf 1611 7 of of IN cord-022526-j9kg00qf 1611 8 endotoxin endotoxin NN cord-022526-j9kg00qf 1611 9 cross cross VBP cord-022526-j9kg00qf 1611 10 the the DT cord-022526-j9kg00qf 1611 11 intact intact JJ cord-022526-j9kg00qf 1611 12 mucosal mucosal JJ cord-022526-j9kg00qf 1611 13 barrier barrier NN cord-022526-j9kg00qf 1611 14 and and CC cord-022526-j9kg00qf 1611 15 reach reach VB cord-022526-j9kg00qf 1611 16 the the DT cord-022526-j9kg00qf 1611 17 portal portal JJ cord-022526-j9kg00qf 1611 18 circulation circulation NN cord-022526-j9kg00qf 1611 19 and and CC cord-022526-j9kg00qf 1611 20 the the DT cord-022526-j9kg00qf 1611 21 liver liver NN cord-022526-j9kg00qf 1611 22 . . . cord-022526-j9kg00qf 1612 1 These these DT cord-022526-j9kg00qf 1612 2 molecules molecule NNS cord-022526-j9kg00qf 1612 3 are be VBP cord-022526-j9kg00qf 1612 4 cleared clear VBN cord-022526-j9kg00qf 1612 5 , , , cord-022526-j9kg00qf 1612 6 however however RB cord-022526-j9kg00qf 1612 7 , , , cord-022526-j9kg00qf 1612 8 by by IN cord-022526-j9kg00qf 1612 9 the the DT cord-022526-j9kg00qf 1612 10 mononuclear mononuclear JJ cord-022526-j9kg00qf 1612 11 phagocytic phagocytic JJ cord-022526-j9kg00qf 1612 12 system system NN cord-022526-j9kg00qf 1612 13 in in IN cord-022526-j9kg00qf 1612 14 the the DT cord-022526-j9kg00qf 1612 15 liver liver NN cord-022526-j9kg00qf 1612 16 and and CC cord-022526-j9kg00qf 1612 17 only only RB cord-022526-j9kg00qf 1612 18 lead lead VB cord-022526-j9kg00qf 1612 19 to to IN cord-022526-j9kg00qf 1612 20 a a DT cord-022526-j9kg00qf 1612 21 localized localize VBN cord-022526-j9kg00qf 1612 22 and and CC cord-022526-j9kg00qf 1612 23 restricted restricted JJ cord-022526-j9kg00qf 1612 24 activation activation NN cord-022526-j9kg00qf 1612 25 of of IN cord-022526-j9kg00qf 1612 26 the the DT cord-022526-j9kg00qf 1612 27 host host NN cord-022526-j9kg00qf 1612 28 immune immune JJ cord-022526-j9kg00qf 1612 29 system system NN cord-022526-j9kg00qf 1612 30 . . . cord-022526-j9kg00qf 1613 1 For for IN cord-022526-j9kg00qf 1613 2 endotoxin endotoxin NN cord-022526-j9kg00qf 1613 3 translocation translocation NN cord-022526-j9kg00qf 1613 4 to to TO cord-022526-j9kg00qf 1613 5 become become VB cord-022526-j9kg00qf 1613 6 detrimental detrimental JJ cord-022526-j9kg00qf 1613 7 , , , cord-022526-j9kg00qf 1613 8 excessive excessive JJ cord-022526-j9kg00qf 1613 9 amounts amount NNS cord-022526-j9kg00qf 1613 10 have have VBP cord-022526-j9kg00qf 1613 11 to to TO cord-022526-j9kg00qf 1613 12 cross cross VB cord-022526-j9kg00qf 1613 13 the the DT cord-022526-j9kg00qf 1613 14 intestinal intestinal JJ cord-022526-j9kg00qf 1613 15 barrier barrier NN cord-022526-j9kg00qf 1613 16 and and CC cord-022526-j9kg00qf 1613 17 overwhelm overwhelm VB cord-022526-j9kg00qf 1613 18 the the DT cord-022526-j9kg00qf 1613 19 mononuclear mononuclear JJ cord-022526-j9kg00qf 1613 20 phagocytic phagocytic JJ cord-022526-j9kg00qf 1613 21 system system NN cord-022526-j9kg00qf 1613 22 or or CC cord-022526-j9kg00qf 1613 23 the the DT cord-022526-j9kg00qf 1613 24 capacity capacity NN cord-022526-j9kg00qf 1613 25 of of IN cord-022526-j9kg00qf 1613 26 the the DT cord-022526-j9kg00qf 1613 27 liver liver NN cord-022526-j9kg00qf 1613 28 to to TO cord-022526-j9kg00qf 1613 29 detoxify detoxify VB cord-022526-j9kg00qf 1613 30 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1613 31 must must MD cord-022526-j9kg00qf 1613 32 be be VB cord-022526-j9kg00qf 1613 33 compromised compromise VBN cord-022526-j9kg00qf 1613 34 . . . cord-022526-j9kg00qf 1614 1 The the DT cord-022526-j9kg00qf 1614 2 latter latter JJ cord-022526-j9kg00qf 1614 3 may may MD cord-022526-j9kg00qf 1614 4 be be VB cord-022526-j9kg00qf 1614 5 a a DT cord-022526-j9kg00qf 1614 6 concern concern NN cord-022526-j9kg00qf 1614 7 in in IN cord-022526-j9kg00qf 1614 8 conditions condition NNS cord-022526-j9kg00qf 1614 9 such such JJ cord-022526-j9kg00qf 1614 10 as as IN cord-022526-j9kg00qf 1614 11 hepatitis hepatitis NN cord-022526-j9kg00qf 1614 12 , , , cord-022526-j9kg00qf 1614 13 cholangiohepatitis cholangiohepatitis NNP cord-022526-j9kg00qf 1614 14 , , , cord-022526-j9kg00qf 1614 15 or or CC cord-022526-j9kg00qf 1614 16 portosystemic portosystemic NN cord-022526-j9kg00qf 1614 17 shunting shunting NN cord-022526-j9kg00qf 1614 18 of of IN cord-022526-j9kg00qf 1614 19 blood blood NN cord-022526-j9kg00qf 1614 20 . . . cord-022526-j9kg00qf 1615 1 Permeability permeability NN cord-022526-j9kg00qf 1615 2 of of IN cord-022526-j9kg00qf 1615 3 the the DT cord-022526-j9kg00qf 1615 4 intestinal intestinal JJ cord-022526-j9kg00qf 1615 5 mucosal mucosal JJ cord-022526-j9kg00qf 1615 6 barrier barrier NN cord-022526-j9kg00qf 1615 7 frequently frequently RB cord-022526-j9kg00qf 1615 8 increases increase VBZ cord-022526-j9kg00qf 1615 9 in in IN cord-022526-j9kg00qf 1615 10 cases case NNS cord-022526-j9kg00qf 1615 11 of of IN cord-022526-j9kg00qf 1615 12 acute acute JJ cord-022526-j9kg00qf 1615 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1615 14 disease disease NN cord-022526-j9kg00qf 1615 15 . . . cord-022526-j9kg00qf 1616 1 Colic colic NN cord-022526-j9kg00qf 1616 2 patients patient NNS cord-022526-j9kg00qf 1616 3 are be VBP cord-022526-j9kg00qf 1616 4 prime prime JJ cord-022526-j9kg00qf 1616 5 candidates candidate NNS cord-022526-j9kg00qf 1616 6 to to IN cord-022526-j9kg00qf 1616 7 development development NN cord-022526-j9kg00qf 1616 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1616 9 , , , cord-022526-j9kg00qf 1616 10 and and CC cord-022526-j9kg00qf 1616 11 plasma plasma NN cord-022526-j9kg00qf 1616 12 endotoxin endotoxin NN cord-022526-j9kg00qf 1616 13 was be VBD cord-022526-j9kg00qf 1616 14 detectable detectable JJ cord-022526-j9kg00qf 1616 15 in in IN cord-022526-j9kg00qf 1616 16 10 10 CD cord-022526-j9kg00qf 1616 17 % % NN cord-022526-j9kg00qf 1616 18 to to IN cord-022526-j9kg00qf 1616 19 40 40 CD cord-022526-j9kg00qf 1616 20 % % NN cord-022526-j9kg00qf 1616 21 of of IN cord-022526-j9kg00qf 1616 22 colic colic NN cord-022526-j9kg00qf 1616 23 patients patient NNS cord-022526-j9kg00qf 1616 24 on on IN cord-022526-j9kg00qf 1616 25 admission admission NN cord-022526-j9kg00qf 1616 26 . . . cord-022526-j9kg00qf 1617 1 14,15 14,15 CD cord-022526-j9kg00qf 1617 2 A a DT cord-022526-j9kg00qf 1617 3 higher high JJR cord-022526-j9kg00qf 1617 4 percentage percentage NN cord-022526-j9kg00qf 1617 5 of of IN cord-022526-j9kg00qf 1617 6 horses horse NNS cord-022526-j9kg00qf 1617 7 tested test VBN cord-022526-j9kg00qf 1617 8 positive positive JJ cord-022526-j9kg00qf 1617 9 for for IN cord-022526-j9kg00qf 1617 10 endotoxin endotoxin NN cord-022526-j9kg00qf 1617 11 when when WRB cord-022526-j9kg00qf 1617 12 only only RB cord-022526-j9kg00qf 1617 13 patients patient NNS cord-022526-j9kg00qf 1617 14 presented present VBN cord-022526-j9kg00qf 1617 15 for for IN cord-022526-j9kg00qf 1617 16 surgical surgical JJ cord-022526-j9kg00qf 1617 17 intervention intervention NN cord-022526-j9kg00qf 1617 18 were be VBD cord-022526-j9kg00qf 1617 19 evaluated evaluate VBN cord-022526-j9kg00qf 1617 20 . . . cord-022526-j9kg00qf 1618 1 15 15 CD cord-022526-j9kg00qf 1618 2 Aside aside RB cord-022526-j9kg00qf 1618 3 from from IN cord-022526-j9kg00qf 1618 4 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1618 5 rupture rupture NN cord-022526-j9kg00qf 1618 6 , , , cord-022526-j9kg00qf 1618 7 increased increase VBD cord-022526-j9kg00qf 1618 8 permeability permeability NN cord-022526-j9kg00qf 1618 9 to to IN cord-022526-j9kg00qf 1618 10 intact intact JJ cord-022526-j9kg00qf 1618 11 bacteria bacteria NNS cord-022526-j9kg00qf 1618 12 or or CC cord-022526-j9kg00qf 1618 13 free free JJ cord-022526-j9kg00qf 1618 14 endotoxin endotoxin NN cord-022526-j9kg00qf 1618 15 molecules molecule NNS cord-022526-j9kg00qf 1618 16 is be VBZ cord-022526-j9kg00qf 1618 17 thought think VBN cord-022526-j9kg00qf 1618 18 to to TO cord-022526-j9kg00qf 1618 19 be be VB cord-022526-j9kg00qf 1618 20 associated associate VBN cord-022526-j9kg00qf 1618 21 most most RBS cord-022526-j9kg00qf 1618 22 commonly commonly RB cord-022526-j9kg00qf 1618 23 with with IN cord-022526-j9kg00qf 1618 24 ischemic ischemic JJ cord-022526-j9kg00qf 1618 25 insults insult NNS cord-022526-j9kg00qf 1618 26 such such JJ cord-022526-j9kg00qf 1618 27 as as IN cord-022526-j9kg00qf 1618 28 strangulating strangulating JJ cord-022526-j9kg00qf 1618 29 obstruction obstruction NN cord-022526-j9kg00qf 1618 30 and and CC cord-022526-j9kg00qf 1618 31 bowel bowel NN cord-022526-j9kg00qf 1618 32 infarction infarction NN cord-022526-j9kg00qf 1618 33 , , , cord-022526-j9kg00qf 1618 34 severe severe JJ cord-022526-j9kg00qf 1618 35 inflammation inflammation NN cord-022526-j9kg00qf 1618 36 as as IN cord-022526-j9kg00qf 1618 37 in in IN cord-022526-j9kg00qf 1618 38 proximal proximal JJ cord-022526-j9kg00qf 1618 39 enteritis enteritis NN cord-022526-j9kg00qf 1618 40 and and CC cord-022526-j9kg00qf 1618 41 colitis colitis NN cord-022526-j9kg00qf 1618 42 , , , cord-022526-j9kg00qf 1618 43 bacterial bacterial JJ cord-022526-j9kg00qf 1618 44 overgrowth overgrowth NN cord-022526-j9kg00qf 1618 45 , , , cord-022526-j9kg00qf 1618 46 and and CC cord-022526-j9kg00qf 1618 47 intraluminal intraluminal JJ cord-022526-j9kg00qf 1618 48 acidosis acidosis NN cord-022526-j9kg00qf 1618 49 , , , cord-022526-j9kg00qf 1618 50 which which WDT cord-022526-j9kg00qf 1618 51 occurs occur VBZ cord-022526-j9kg00qf 1618 52 with with IN cord-022526-j9kg00qf 1618 53 grain grain NN cord-022526-j9kg00qf 1618 54 overload overload NN cord-022526-j9kg00qf 1618 55 . . . cord-022526-j9kg00qf 1619 1 16 16 CD cord-022526-j9kg00qf 1619 2 , , , cord-022526-j9kg00qf 1619 3 17 17 CD cord-022526-j9kg00qf 1619 4 One one CD cord-022526-j9kg00qf 1619 5 study study NN cord-022526-j9kg00qf 1619 6 , , , cord-022526-j9kg00qf 1619 7 however however RB cord-022526-j9kg00qf 1619 8 , , , cord-022526-j9kg00qf 1619 9 found find VBD cord-022526-j9kg00qf 1619 10 no no DT cord-022526-j9kg00qf 1619 11 difference difference NN cord-022526-j9kg00qf 1619 12 in in IN cord-022526-j9kg00qf 1619 13 plasma plasma NN cord-022526-j9kg00qf 1619 14 endotoxin endotoxin NN cord-022526-j9kg00qf 1619 15 detection detection NN cord-022526-j9kg00qf 1619 16 between between IN cord-022526-j9kg00qf 1619 17 disease disease NN cord-022526-j9kg00qf 1619 18 groups group NNS cord-022526-j9kg00qf 1619 19 , , , cord-022526-j9kg00qf 1619 20 therefore therefore RB cord-022526-j9kg00qf 1619 21 emphasizing emphasize VBG cord-022526-j9kg00qf 1619 22 the the DT cord-022526-j9kg00qf 1619 23 fact fact NN cord-022526-j9kg00qf 1619 24 that that IN cord-022526-j9kg00qf 1619 25 any any DT cord-022526-j9kg00qf 1619 26 disease disease NN cord-022526-j9kg00qf 1619 27 of of IN cord-022526-j9kg00qf 1619 28 the the DT cord-022526-j9kg00qf 1619 29 abdominal abdominal JJ cord-022526-j9kg00qf 1619 30 cavity cavity NN cord-022526-j9kg00qf 1619 31 can can MD cord-022526-j9kg00qf 1619 32 induce induce VB cord-022526-j9kg00qf 1619 33 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1619 34 in in IN cord-022526-j9kg00qf 1619 35 horses horse NNS cord-022526-j9kg00qf 1619 36 . . . cord-022526-j9kg00qf 1620 1 In in IN cord-022526-j9kg00qf 1620 2 the the DT cord-022526-j9kg00qf 1620 3 same same JJ cord-022526-j9kg00qf 1620 4 study study NN cord-022526-j9kg00qf 1620 5 , , , cord-022526-j9kg00qf 1620 6 endotoxin endotoxin NN cord-022526-j9kg00qf 1620 7 was be VBD cord-022526-j9kg00qf 1620 8 approximately approximately RB cord-022526-j9kg00qf 1620 9 3 3 CD cord-022526-j9kg00qf 1620 10 times time NNS cord-022526-j9kg00qf 1620 11 more more RBR cord-022526-j9kg00qf 1620 12 likely likely JJ cord-022526-j9kg00qf 1620 13 to to TO cord-022526-j9kg00qf 1620 14 be be VB cord-022526-j9kg00qf 1620 15 detected detect VBN cord-022526-j9kg00qf 1620 16 in in IN cord-022526-j9kg00qf 1620 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 1620 18 fluid fluid NN cord-022526-j9kg00qf 1620 19 as as IN cord-022526-j9kg00qf 1620 20 opposed oppose VBN cord-022526-j9kg00qf 1620 21 to to IN cord-022526-j9kg00qf 1620 22 plasma plasma NN cord-022526-j9kg00qf 1620 23 samples sample NNS cord-022526-j9kg00qf 1620 24 . . . cord-022526-j9kg00qf 1621 1 Similarly similarly RB cord-022526-j9kg00qf 1621 2 , , , cord-022526-j9kg00qf 1621 3 higher high JJR cord-022526-j9kg00qf 1621 4 cytokine cytokine NN cord-022526-j9kg00qf 1621 5 concentrations concentration NNS cord-022526-j9kg00qf 1621 6 have have VBP cord-022526-j9kg00qf 1621 7 been be VBN cord-022526-j9kg00qf 1621 8 measured measure VBN cord-022526-j9kg00qf 1621 9 in in IN cord-022526-j9kg00qf 1621 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 1621 11 fluid fluid NN cord-022526-j9kg00qf 1621 12 than than IN cord-022526-j9kg00qf 1621 13 in in IN cord-022526-j9kg00qf 1621 14 plasma plasma NN cord-022526-j9kg00qf 1621 15 . . . cord-022526-j9kg00qf 1622 1 The the DT cord-022526-j9kg00qf 1622 2 likely likely JJ cord-022526-j9kg00qf 1622 3 explanation explanation NN cord-022526-j9kg00qf 1622 4 for for IN cord-022526-j9kg00qf 1622 5 these these DT cord-022526-j9kg00qf 1622 6 findings finding NNS cord-022526-j9kg00qf 1622 7 is be VBZ cord-022526-j9kg00qf 1622 8 a a DT cord-022526-j9kg00qf 1622 9 local local JJ cord-022526-j9kg00qf 1622 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 1622 11 response response NN cord-022526-j9kg00qf 1622 12 in in IN cord-022526-j9kg00qf 1622 13 the the DT cord-022526-j9kg00qf 1622 14 peritoneal peritoneal JJ cord-022526-j9kg00qf 1622 15 cavity cavity NN cord-022526-j9kg00qf 1622 16 elicited elicit VBN cord-022526-j9kg00qf 1622 17 by by IN cord-022526-j9kg00qf 1622 18 translocated translocate VBN cord-022526-j9kg00qf 1622 19 bacteria bacteria NNS cord-022526-j9kg00qf 1622 20 and/or and/or CC cord-022526-j9kg00qf 1622 21 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1622 22 molecules molecule NNS cord-022526-j9kg00qf 1622 23 before before IN cord-022526-j9kg00qf 1622 24 their -PRON- PRP$ cord-022526-j9kg00qf 1622 25 absorption absorption NN cord-022526-j9kg00qf 1622 26 into into IN cord-022526-j9kg00qf 1622 27 the the DT cord-022526-j9kg00qf 1622 28 systemic systemic JJ cord-022526-j9kg00qf 1622 29 circulation circulation NN cord-022526-j9kg00qf 1622 30 . . . cord-022526-j9kg00qf 1623 1 14 14 CD cord-022526-j9kg00qf 1624 1 Although although IN cord-022526-j9kg00qf 1624 2 certainly certainly RB cord-022526-j9kg00qf 1624 3 the the DT cord-022526-j9kg00qf 1624 4 most most RBS cord-022526-j9kg00qf 1624 5 important important JJ cord-022526-j9kg00qf 1624 6 factor factor NN cord-022526-j9kg00qf 1624 7 in in IN cord-022526-j9kg00qf 1624 8 horses horse NNS cord-022526-j9kg00qf 1624 9 , , , cord-022526-j9kg00qf 1624 10 conditions condition NNS cord-022526-j9kg00qf 1624 11 other other JJ cord-022526-j9kg00qf 1624 12 than than IN cord-022526-j9kg00qf 1624 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1624 14 disease disease NN cord-022526-j9kg00qf 1624 15 may may MD cord-022526-j9kg00qf 1624 16 result result VB cord-022526-j9kg00qf 1624 17 in in IN cord-022526-j9kg00qf 1624 18 translocation translocation NN cord-022526-j9kg00qf 1624 19 of of IN cord-022526-j9kg00qf 1624 20 endotoxin endotoxin NN cord-022526-j9kg00qf 1624 21 and and CC cord-022526-j9kg00qf 1624 22 bacteria bacteria NNS cord-022526-j9kg00qf 1624 23 . . . cord-022526-j9kg00qf 1625 1 In in IN cord-022526-j9kg00qf 1625 2 experimental experimental JJ cord-022526-j9kg00qf 1625 3 studies study NNS cord-022526-j9kg00qf 1625 4 using use VBG cord-022526-j9kg00qf 1625 5 laboratory laboratory NN cord-022526-j9kg00qf 1625 6 animals animal NNS cord-022526-j9kg00qf 1625 7 , , , cord-022526-j9kg00qf 1625 8 entry entry NN cord-022526-j9kg00qf 1625 9 of of IN cord-022526-j9kg00qf 1625 10 gutassociated gutassociate VBN cord-022526-j9kg00qf 1625 11 bacteria bacteria NNS cord-022526-j9kg00qf 1625 12 into into IN cord-022526-j9kg00qf 1625 13 the the DT cord-022526-j9kg00qf 1625 14 lymphatic lymphatic JJ cord-022526-j9kg00qf 1625 15 system system NN cord-022526-j9kg00qf 1625 16 was be VBD cord-022526-j9kg00qf 1625 17 demonstrated demonstrate VBN cord-022526-j9kg00qf 1625 18 after after IN cord-022526-j9kg00qf 1625 19 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 1625 20 shock shock NN cord-022526-j9kg00qf 1625 21 , , , cord-022526-j9kg00qf 1625 22 burn burn NN cord-022526-j9kg00qf 1625 23 injuries injury NNS cord-022526-j9kg00qf 1625 24 , , , cord-022526-j9kg00qf 1625 25 trauma trauma NN cord-022526-j9kg00qf 1625 26 , , , cord-022526-j9kg00qf 1625 27 malnutrition malnutrition NN cord-022526-j9kg00qf 1625 28 , , , cord-022526-j9kg00qf 1625 29 and and CC cord-022526-j9kg00qf 1625 30 starvation starvation NN cord-022526-j9kg00qf 1625 31 . . . cord-022526-j9kg00qf 1626 1 [ [ -LRB- cord-022526-j9kg00qf 1626 2 18 18 CD cord-022526-j9kg00qf 1626 3 ] ] -RRB- cord-022526-j9kg00qf 1626 4 [ [ -LRB- cord-022526-j9kg00qf 1626 5 19 19 CD cord-022526-j9kg00qf 1626 6 ] ] -RRB- cord-022526-j9kg00qf 1626 7 [ [ -LRB- cord-022526-j9kg00qf 1626 8 20 20 CD cord-022526-j9kg00qf 1626 9 ] ] -RRB- cord-022526-j9kg00qf 1627 1 Furthermore furthermore RB cord-022526-j9kg00qf 1627 2 , , , cord-022526-j9kg00qf 1627 3 endotoxin endotoxin NN cord-022526-j9kg00qf 1627 4 itself -PRON- PRP cord-022526-j9kg00qf 1627 5 caused cause VBD cord-022526-j9kg00qf 1627 6 bacterial bacterial JJ cord-022526-j9kg00qf 1627 7 translocation translocation NN cord-022526-j9kg00qf 1627 8 into into IN cord-022526-j9kg00qf 1627 9 mesenteric mesenteric JJ cord-022526-j9kg00qf 1627 10 lymph lymph NN cord-022526-j9kg00qf 1627 11 nodes node NNS cord-022526-j9kg00qf 1627 12 after after IN cord-022526-j9kg00qf 1627 13 intraperitoneal intraperitoneal JJ cord-022526-j9kg00qf 1627 14 administration administration NN cord-022526-j9kg00qf 1627 15 to to IN cord-022526-j9kg00qf 1627 16 mice mouse NNS cord-022526-j9kg00qf 1627 17 . . . cord-022526-j9kg00qf 1628 1 21 21 CD cord-022526-j9kg00qf 1629 1 These these DT cord-022526-j9kg00qf 1629 2 findings finding NNS cord-022526-j9kg00qf 1629 3 have have VBP cord-022526-j9kg00qf 1629 4 received receive VBN cord-022526-j9kg00qf 1629 5 much much JJ cord-022526-j9kg00qf 1629 6 attention attention NN cord-022526-j9kg00qf 1629 7 in in IN cord-022526-j9kg00qf 1629 8 the the DT cord-022526-j9kg00qf 1629 9 literature literature NN cord-022526-j9kg00qf 1629 10 concerning concern VBG cord-022526-j9kg00qf 1629 11 human human JJ cord-022526-j9kg00qf 1629 12 patients patient NNS cord-022526-j9kg00qf 1629 13 because because IN cord-022526-j9kg00qf 1629 14 they -PRON- PRP cord-022526-j9kg00qf 1629 15 serve serve VBP cord-022526-j9kg00qf 1629 16 to to TO cord-022526-j9kg00qf 1629 17 explain explain VB cord-022526-j9kg00qf 1629 18 cases case NNS cord-022526-j9kg00qf 1629 19 of of IN cord-022526-j9kg00qf 1629 20 endotoxic endotoxic JJ cord-022526-j9kg00qf 1629 21 shock shock NN cord-022526-j9kg00qf 1629 22 in in IN cord-022526-j9kg00qf 1629 23 the the DT cord-022526-j9kg00qf 1629 24 absence absence NN cord-022526-j9kg00qf 1629 25 of of IN cord-022526-j9kg00qf 1629 26 demonstrable demonstrable JJ cord-022526-j9kg00qf 1629 27 bacterial bacterial JJ cord-022526-j9kg00qf 1629 28 infection infection NN cord-022526-j9kg00qf 1629 29 . . . cord-022526-j9kg00qf 1630 1 One one PRP cord-022526-j9kg00qf 1630 2 should should MD cord-022526-j9kg00qf 1630 3 keep keep VB cord-022526-j9kg00qf 1630 4 in in IN cord-022526-j9kg00qf 1630 5 mind mind NN cord-022526-j9kg00qf 1630 6 the the DT cord-022526-j9kg00qf 1630 7 possibility possibility NN cord-022526-j9kg00qf 1630 8 of of IN cord-022526-j9kg00qf 1630 9 translocation translocation NN cord-022526-j9kg00qf 1630 10 when when WRB cord-022526-j9kg00qf 1630 11 evaluating evaluate VBG cord-022526-j9kg00qf 1630 12 cases case NNS cord-022526-j9kg00qf 1630 13 of of IN cord-022526-j9kg00qf 1630 14 presumed presume VBN cord-022526-j9kg00qf 1630 15 systemic systemic JJ cord-022526-j9kg00qf 1630 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 1630 17 response response NN cord-022526-j9kg00qf 1630 18 syndrome syndrome NN cord-022526-j9kg00qf 1630 19 in in IN cord-022526-j9kg00qf 1630 20 horses horse NNS cord-022526-j9kg00qf 1630 21 , , , cord-022526-j9kg00qf 1630 22 in in IN cord-022526-j9kg00qf 1630 23 which which WDT cord-022526-j9kg00qf 1630 24 one one PRP cord-022526-j9kg00qf 1630 25 can can MD cord-022526-j9kg00qf 1630 26 not not RB cord-022526-j9kg00qf 1630 27 demonstrate demonstrate VB cord-022526-j9kg00qf 1630 28 bacterial bacterial JJ cord-022526-j9kg00qf 1630 29 infection infection NN cord-022526-j9kg00qf 1630 30 or or CC cord-022526-j9kg00qf 1630 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1630 32 disease disease NN cord-022526-j9kg00qf 1630 33 . . . cord-022526-j9kg00qf 1631 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1631 2 translocation translocation NN cord-022526-j9kg00qf 1631 3 also also RB cord-022526-j9kg00qf 1631 4 may may MD cord-022526-j9kg00qf 1631 5 be be VB cord-022526-j9kg00qf 1631 6 associated associate VBN cord-022526-j9kg00qf 1631 7 with with IN cord-022526-j9kg00qf 1631 8 strenuous strenuous JJ cord-022526-j9kg00qf 1631 9 exercise exercise NN cord-022526-j9kg00qf 1631 10 , , , cord-022526-j9kg00qf 1631 11 which which WDT cord-022526-j9kg00qf 1631 12 results result VBZ cord-022526-j9kg00qf 1631 13 in in IN cord-022526-j9kg00qf 1631 14 reduced reduce VBN cord-022526-j9kg00qf 1631 15 splanchnic splanchnic JJ cord-022526-j9kg00qf 1631 16 blood blood NN cord-022526-j9kg00qf 1631 17 flow flow NN cord-022526-j9kg00qf 1631 18 , , , cord-022526-j9kg00qf 1631 19 hypoxemia hypoxemia NN cord-022526-j9kg00qf 1631 20 , , , cord-022526-j9kg00qf 1631 21 and and CC cord-022526-j9kg00qf 1631 22 a a DT cord-022526-j9kg00qf 1631 23 higher high JJR cord-022526-j9kg00qf 1631 24 body body NN cord-022526-j9kg00qf 1631 25 temperature temperature NN cord-022526-j9kg00qf 1631 26 . . . cord-022526-j9kg00qf 1632 1 In in IN cord-022526-j9kg00qf 1632 2 fit fit JJ cord-022526-j9kg00qf 1632 3 racehorses racehorse NNS cord-022526-j9kg00qf 1632 4 a a DT cord-022526-j9kg00qf 1632 5 significantly significantly RB cord-022526-j9kg00qf 1632 6 increased increase VBN cord-022526-j9kg00qf 1632 7 mean mean JJ cord-022526-j9kg00qf 1632 8 plasma plasma NN cord-022526-j9kg00qf 1632 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1632 10 concentration concentration NN cord-022526-j9kg00qf 1632 11 was be VBD cord-022526-j9kg00qf 1632 12 found find VBN cord-022526-j9kg00qf 1632 13 after after IN cord-022526-j9kg00qf 1632 14 racing race VBG cord-022526-j9kg00qf 1632 15 , , , cord-022526-j9kg00qf 1632 16 whereas whereas IN cord-022526-j9kg00qf 1632 17 antilipopolysaccharide antilipopolysaccharide NN cord-022526-j9kg00qf 1632 18 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 1632 19 G g NN cord-022526-j9kg00qf 1632 20 levels level NNS cord-022526-j9kg00qf 1632 21 were be VBD cord-022526-j9kg00qf 1632 22 decreased decrease VBN cord-022526-j9kg00qf 1632 23 . . . cord-022526-j9kg00qf 1633 1 Fit fit JJ cord-022526-j9kg00qf 1633 2 horses horse NNS cord-022526-j9kg00qf 1633 3 showed show VBD cord-022526-j9kg00qf 1633 4 significantly significantly RB cord-022526-j9kg00qf 1633 5 higher high JJR cord-022526-j9kg00qf 1633 6 antilipopolysaccharide antilipopolysaccharide NN cord-022526-j9kg00qf 1633 7 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 1633 8 G g NN cord-022526-j9kg00qf 1633 9 concentrations concentration NNS cord-022526-j9kg00qf 1633 10 at at IN cord-022526-j9kg00qf 1633 11 rest rest NN cord-022526-j9kg00qf 1633 12 than than IN cord-022526-j9kg00qf 1633 13 sedentary sedentary JJ cord-022526-j9kg00qf 1633 14 controls control NNS cord-022526-j9kg00qf 1633 15 , , , cord-022526-j9kg00qf 1633 16 suggesting suggest VBG cord-022526-j9kg00qf 1633 17 leakage leakage NN cord-022526-j9kg00qf 1633 18 of of IN cord-022526-j9kg00qf 1633 19 small small JJ cord-022526-j9kg00qf 1633 20 amounts amount NNS cord-022526-j9kg00qf 1633 21 of of IN cord-022526-j9kg00qf 1633 22 endotoxin endotoxin NN cord-022526-j9kg00qf 1633 23 from from IN cord-022526-j9kg00qf 1633 24 the the DT cord-022526-j9kg00qf 1633 25 intestinal intestinal JJ cord-022526-j9kg00qf 1633 26 lumen lumen NN cord-022526-j9kg00qf 1633 27 during during IN cord-022526-j9kg00qf 1633 28 training training NN cord-022526-j9kg00qf 1633 29 and and CC cord-022526-j9kg00qf 1633 30 racing racing NN cord-022526-j9kg00qf 1633 31 . . . cord-022526-j9kg00qf 1634 1 22 22 CD cord-022526-j9kg00qf 1635 1 The the DT cord-022526-j9kg00qf 1635 2 clinical clinical JJ cord-022526-j9kg00qf 1635 3 significance significance NN cord-022526-j9kg00qf 1635 4 of of IN cord-022526-j9kg00qf 1635 5 these these DT cord-022526-j9kg00qf 1635 6 findings finding NNS cord-022526-j9kg00qf 1635 7 requires require VBZ cord-022526-j9kg00qf 1635 8 further further JJ cord-022526-j9kg00qf 1635 9 investigation investigation NN cord-022526-j9kg00qf 1635 10 . . . cord-022526-j9kg00qf 1636 1 The the DT cord-022526-j9kg00qf 1636 2 initiating initiate VBG cord-022526-j9kg00qf 1636 3 event event NN cord-022526-j9kg00qf 1636 4 in in IN cord-022526-j9kg00qf 1636 5 the the DT cord-022526-j9kg00qf 1636 6 pathophysiology pathophysiology NN cord-022526-j9kg00qf 1636 7 of of IN cord-022526-j9kg00qf 1636 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1636 9 is be VBZ cord-022526-j9kg00qf 1636 10 the the DT cord-022526-j9kg00qf 1636 11 activation activation NN cord-022526-j9kg00qf 1636 12 of of IN cord-022526-j9kg00qf 1636 13 lipopolysaccharideresponsive lipopolysaccharideresponsive JJ cord-022526-j9kg00qf 1636 14 cells cell NNS cord-022526-j9kg00qf 1636 15 by by IN cord-022526-j9kg00qf 1636 16 endotoxin endotoxin NN cord-022526-j9kg00qf 1636 17 , , , cord-022526-j9kg00qf 1636 18 resulting result VBG cord-022526-j9kg00qf 1636 19 in in IN cord-022526-j9kg00qf 1636 20 altered alter VBN cord-022526-j9kg00qf 1636 21 cellular cellular JJ cord-022526-j9kg00qf 1636 22 functions function NNS cord-022526-j9kg00qf 1636 23 and and CC cord-022526-j9kg00qf 1636 24 increased increase VBN cord-022526-j9kg00qf 1636 25 expression expression NN cord-022526-j9kg00qf 1636 26 of of IN cord-022526-j9kg00qf 1636 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 1636 28 mediators mediator NNS cord-022526-j9kg00qf 1636 29 . . . cord-022526-j9kg00qf 1637 1 Immune immune NN cord-022526-j9kg00qf 1637 2 cells cell NNS cord-022526-j9kg00qf 1637 3 such such JJ cord-022526-j9kg00qf 1637 4 as as IN cord-022526-j9kg00qf 1637 5 macrophages macrophage NNS cord-022526-j9kg00qf 1637 6 , , , cord-022526-j9kg00qf 1637 7 which which WDT cord-022526-j9kg00qf 1637 8 are be VBP cord-022526-j9kg00qf 1637 9 the the DT cord-022526-j9kg00qf 1637 10 first first JJ cord-022526-j9kg00qf 1637 11 to to TO cord-022526-j9kg00qf 1637 12 encounter encounter VB cord-022526-j9kg00qf 1637 13 endotoxin endotoxin NN cord-022526-j9kg00qf 1637 14 , , , cord-022526-j9kg00qf 1637 15 respond respond VB cord-022526-j9kg00qf 1637 16 to to IN cord-022526-j9kg00qf 1637 17 minute minute JJ cord-022526-j9kg00qf 1637 18 amounts amount NNS cord-022526-j9kg00qf 1637 19 of of IN cord-022526-j9kg00qf 1637 20 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1637 21 , , , cord-022526-j9kg00qf 1637 22 which which WDT cord-022526-j9kg00qf 1637 23 usually usually RB cord-022526-j9kg00qf 1637 24 allows allow VBZ cord-022526-j9kg00qf 1637 25 them -PRON- PRP cord-022526-j9kg00qf 1637 26 to to TO cord-022526-j9kg00qf 1637 27 eliminate eliminate VB cord-022526-j9kg00qf 1637 28 gram gram NN cord-022526-j9kg00qf 1637 29 - - HYPH cord-022526-j9kg00qf 1637 30 negative negative JJ cord-022526-j9kg00qf 1637 31 bacteria bacteria NNS cord-022526-j9kg00qf 1637 32 and and CC cord-022526-j9kg00qf 1637 33 free free JJ cord-022526-j9kg00qf 1637 34 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1637 35 molecules molecule NNS cord-022526-j9kg00qf 1637 36 efficiently efficiently RB cord-022526-j9kg00qf 1637 37 . . . cord-022526-j9kg00qf 1638 1 An an DT cord-022526-j9kg00qf 1638 2 important important JJ cord-022526-j9kg00qf 1638 3 factor factor NN cord-022526-j9kg00qf 1638 4 in in IN cord-022526-j9kg00qf 1638 5 the the DT cord-022526-j9kg00qf 1638 6 exquisite exquisite JJ cord-022526-j9kg00qf 1638 7 sensitivity sensitivity NN cord-022526-j9kg00qf 1638 8 to to IN cord-022526-j9kg00qf 1638 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1638 10 is be VBZ cord-022526-j9kg00qf 1638 11 the the DT cord-022526-j9kg00qf 1638 12 presence presence NN cord-022526-j9kg00qf 1638 13 of of IN cord-022526-j9kg00qf 1638 14 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1638 15 - - HYPH cord-022526-j9kg00qf 1638 16 binding bind VBG cord-022526-j9kg00qf 1638 17 protein protein NN cord-022526-j9kg00qf 1638 18 ( ( -LRB- cord-022526-j9kg00qf 1638 19 LBP LBP NNP cord-022526-j9kg00qf 1638 20 ) ) -RRB- cord-022526-j9kg00qf 1638 21 . . . cord-022526-j9kg00qf 1639 1 4 4 LS cord-022526-j9kg00qf 1639 2 LBP LBP NNP cord-022526-j9kg00qf 1639 3 is be VBZ cord-022526-j9kg00qf 1639 4 an an DT cord-022526-j9kg00qf 1639 5 approximately approximately RB cord-022526-j9kg00qf 1639 6 60-kd 60-kd CD cord-022526-j9kg00qf 1639 7 plasma plasma NN cord-022526-j9kg00qf 1639 8 glycoprotein glycoprotein NN cord-022526-j9kg00qf 1639 9 23 23 CD cord-022526-j9kg00qf 1639 10 synthesized synthesize VBN cord-022526-j9kg00qf 1639 11 by by IN cord-022526-j9kg00qf 1639 12 hepatocytes hepatocyte NNS cord-022526-j9kg00qf 1639 13 24 24 CD cord-022526-j9kg00qf 1639 14 and and CC cord-022526-j9kg00qf 1639 15 belongs belong VBZ cord-022526-j9kg00qf 1639 16 to to IN cord-022526-j9kg00qf 1639 17 the the DT cord-022526-j9kg00qf 1639 18 group group NN cord-022526-j9kg00qf 1639 19 of of IN cord-022526-j9kg00qf 1639 20 acute acute JJ cord-022526-j9kg00qf 1639 21 phase phase NN cord-022526-j9kg00qf 1639 22 proteins protein NNS cord-022526-j9kg00qf 1639 23 . . . cord-022526-j9kg00qf 1640 1 Under under IN cord-022526-j9kg00qf 1640 2 the the DT cord-022526-j9kg00qf 1640 3 control control NN cord-022526-j9kg00qf 1640 4 of of IN cord-022526-j9kg00qf 1640 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 1640 6 agents agent NNS cord-022526-j9kg00qf 1640 7 and and CC cord-022526-j9kg00qf 1640 8 cytokines cytokine NNS cord-022526-j9kg00qf 1640 9 , , , cord-022526-j9kg00qf 1640 10 LBP LBP NNP cord-022526-j9kg00qf 1640 11 concentration concentration NN cord-022526-j9kg00qf 1640 12 in in IN cord-022526-j9kg00qf 1640 13 plasma plasma NN cord-022526-j9kg00qf 1640 14 increases increase VBZ cord-022526-j9kg00qf 1640 15 approximately approximately RB cord-022526-j9kg00qf 1640 16 100-fold 100-fold CD cord-022526-j9kg00qf 1640 17 within within IN cord-022526-j9kg00qf 1640 18 24 24 CD cord-022526-j9kg00qf 1640 19 hours hour NNS cord-022526-j9kg00qf 1640 20 of of IN cord-022526-j9kg00qf 1640 21 an an DT cord-022526-j9kg00qf 1640 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 1640 23 stimulus stimulus NN cord-022526-j9kg00qf 1640 24 . . . cord-022526-j9kg00qf 1641 1 25 25 CD cord-022526-j9kg00qf 1642 1 The the DT cord-022526-j9kg00qf 1642 2 main main JJ cord-022526-j9kg00qf 1642 3 function function NN cord-022526-j9kg00qf 1642 4 of of IN cord-022526-j9kg00qf 1642 5 LBP LBP NNP cord-022526-j9kg00qf 1642 6 is be VBZ cord-022526-j9kg00qf 1642 7 to to TO cord-022526-j9kg00qf 1642 8 transfer transfer VB cord-022526-j9kg00qf 1642 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1642 10 to to IN cord-022526-j9kg00qf 1642 11 endotoxin endotoxin NN cord-022526-j9kg00qf 1642 12 - - HYPH cord-022526-j9kg00qf 1642 13 responsive responsive JJ cord-022526-j9kg00qf 1642 14 cells cell NNS cord-022526-j9kg00qf 1642 15 , , , cord-022526-j9kg00qf 1642 16 which which WDT cord-022526-j9kg00qf 1642 17 include include VBP cord-022526-j9kg00qf 1642 18 mononuclear mononuclear JJ cord-022526-j9kg00qf 1642 19 phagocytes phagocyte NNS cord-022526-j9kg00qf 1642 20 , , , cord-022526-j9kg00qf 1642 21 neutrophils neutrophil NNS cord-022526-j9kg00qf 1642 22 , , , cord-022526-j9kg00qf 1642 23 lymphocytes lymphocyte NNS cord-022526-j9kg00qf 1642 24 , , , cord-022526-j9kg00qf 1642 25 and and CC cord-022526-j9kg00qf 1642 26 endothelial endothelial JJ cord-022526-j9kg00qf 1642 27 cells cell NNS cord-022526-j9kg00qf 1642 28 . . . cord-022526-j9kg00qf 1643 1 The the DT cord-022526-j9kg00qf 1643 2 importance importance NN cord-022526-j9kg00qf 1643 3 of of IN cord-022526-j9kg00qf 1643 4 a a DT cord-022526-j9kg00qf 1643 5 highly highly RB cord-022526-j9kg00qf 1643 6 sensitive sensitive JJ cord-022526-j9kg00qf 1643 7 response response NN cord-022526-j9kg00qf 1643 8 to to IN cord-022526-j9kg00qf 1643 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1643 10 for for IN cord-022526-j9kg00qf 1643 11 protection protection NN cord-022526-j9kg00qf 1643 12 against against IN cord-022526-j9kg00qf 1643 13 gram gram NN cord-022526-j9kg00qf 1643 14 - - HYPH cord-022526-j9kg00qf 1643 15 negative negative JJ cord-022526-j9kg00qf 1643 16 bacterial bacterial JJ cord-022526-j9kg00qf 1643 17 infection infection NN cord-022526-j9kg00qf 1643 18 is be VBZ cord-022526-j9kg00qf 1643 19 demonstrated demonstrate VBN cord-022526-j9kg00qf 1643 20 in in IN cord-022526-j9kg00qf 1643 21 experiments experiment NNS cord-022526-j9kg00qf 1643 22 using use VBG cord-022526-j9kg00qf 1643 23 LBP LBP NNP cord-022526-j9kg00qf 1643 24 " " `` cord-022526-j9kg00qf 1643 25 knock knock VB cord-022526-j9kg00qf 1643 26 - - HYPH cord-022526-j9kg00qf 1643 27 out out RP cord-022526-j9kg00qf 1643 28 " " '' cord-022526-j9kg00qf 1643 29 mice mouse NNS cord-022526-j9kg00qf 1643 30 ( ( -LRB- cord-022526-j9kg00qf 1643 31 mice mouse NNS cord-022526-j9kg00qf 1643 32 that that WDT cord-022526-j9kg00qf 1643 33 lack lack VBP cord-022526-j9kg00qf 1643 34 the the DT cord-022526-j9kg00qf 1643 35 LBP LBP NNP cord-022526-j9kg00qf 1643 36 gene gene NN cord-022526-j9kg00qf 1643 37 and and CC cord-022526-j9kg00qf 1643 38 are be VBP cord-022526-j9kg00qf 1643 39 therefore therefore RB cord-022526-j9kg00qf 1643 40 unable unable JJ cord-022526-j9kg00qf 1643 41 to to TO cord-022526-j9kg00qf 1643 42 synthesize synthesize VB cord-022526-j9kg00qf 1643 43 LBP LBP NNP cord-022526-j9kg00qf 1643 44 ) ) -RRB- cord-022526-j9kg00qf 1643 45 . . . cord-022526-j9kg00qf 1644 1 Although although IN cord-022526-j9kg00qf 1644 2 these these DT cord-022526-j9kg00qf 1644 3 animals animal NNS cord-022526-j9kg00qf 1644 4 are be VBP cord-022526-j9kg00qf 1644 5 resistant resistant JJ cord-022526-j9kg00qf 1644 6 to to IN cord-022526-j9kg00qf 1644 7 the the DT cord-022526-j9kg00qf 1644 8 effects effect NNS cord-022526-j9kg00qf 1644 9 of of IN cord-022526-j9kg00qf 1644 10 isolated isolate VBN cord-022526-j9kg00qf 1644 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1644 12 , , , cord-022526-j9kg00qf 1644 13 they -PRON- PRP cord-022526-j9kg00qf 1644 14 are be VBP cord-022526-j9kg00qf 1644 15 unable unable JJ cord-022526-j9kg00qf 1644 16 to to TO cord-022526-j9kg00qf 1644 17 control control VB cord-022526-j9kg00qf 1644 18 bacterial bacterial JJ cord-022526-j9kg00qf 1644 19 infection infection NN cord-022526-j9kg00qf 1644 20 and and CC cord-022526-j9kg00qf 1644 21 rapidly rapidly RB cord-022526-j9kg00qf 1644 22 succumb succumb VB cord-022526-j9kg00qf 1644 23 . . . cord-022526-j9kg00qf 1645 1 26 26 CD cord-022526-j9kg00qf 1646 1 Despite despite IN cord-022526-j9kg00qf 1646 2 its -PRON- PRP$ cord-022526-j9kg00qf 1646 3 crucial crucial JJ cord-022526-j9kg00qf 1646 4 importance importance NN cord-022526-j9kg00qf 1646 5 for for IN cord-022526-j9kg00qf 1646 6 an an DT cord-022526-j9kg00qf 1646 7 effective effective JJ cord-022526-j9kg00qf 1646 8 host host NN cord-022526-j9kg00qf 1646 9 defense defense NN cord-022526-j9kg00qf 1646 10 , , , cord-022526-j9kg00qf 1646 11 LBP LBP NNP cord-022526-j9kg00qf 1646 12 is be VBZ cord-022526-j9kg00qf 1646 13 not not RB cord-022526-j9kg00qf 1646 14 essential essential JJ cord-022526-j9kg00qf 1646 15 for for IN cord-022526-j9kg00qf 1646 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1646 17 - - HYPH cord-022526-j9kg00qf 1646 18 receptor receptor NN cord-022526-j9kg00qf 1646 19 interaction interaction NN cord-022526-j9kg00qf 1646 20 per per FW cord-022526-j9kg00qf 1646 21 se se FW cord-022526-j9kg00qf 1646 22 , , , cord-022526-j9kg00qf 1646 23 because because IN cord-022526-j9kg00qf 1646 24 high high JJ cord-022526-j9kg00qf 1646 25 concentrations concentration NNS cord-022526-j9kg00qf 1646 26 of of IN cord-022526-j9kg00qf 1646 27 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1646 28 can can MD cord-022526-j9kg00qf 1646 29 activate activate VB cord-022526-j9kg00qf 1646 30 cells cell NNS cord-022526-j9kg00qf 1646 31 in in IN cord-022526-j9kg00qf 1646 32 the the DT cord-022526-j9kg00qf 1646 33 absence absence NN cord-022526-j9kg00qf 1646 34 of of IN cord-022526-j9kg00qf 1646 35 LBP LBP NNP cord-022526-j9kg00qf 1646 36 . . . cord-022526-j9kg00qf 1647 1 27 27 CD cord-022526-j9kg00qf 1648 1 Aside aside RB cord-022526-j9kg00qf 1648 2 from from IN cord-022526-j9kg00qf 1648 3 its -PRON- PRP$ cord-022526-j9kg00qf 1648 4 role role NN cord-022526-j9kg00qf 1648 5 as as IN cord-022526-j9kg00qf 1648 6 a a DT cord-022526-j9kg00qf 1648 7 catalyst catalyst NN cord-022526-j9kg00qf 1648 8 of of IN cord-022526-j9kg00qf 1648 9 cellular cellular JJ cord-022526-j9kg00qf 1648 10 activation activation NN cord-022526-j9kg00qf 1648 11 by by IN cord-022526-j9kg00qf 1648 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1648 13 , , , cord-022526-j9kg00qf 1648 14 LBP LBP NNP cord-022526-j9kg00qf 1648 15 has have VBZ cord-022526-j9kg00qf 1648 16 opsonizing opsonize VBG cord-022526-j9kg00qf 1648 17 activity activity NN cord-022526-j9kg00qf 1648 18 28 28 CD cord-022526-j9kg00qf 1648 19 and and CC cord-022526-j9kg00qf 1648 20 participates participate VBZ cord-022526-j9kg00qf 1648 21 in in IN cord-022526-j9kg00qf 1648 22 the the DT cord-022526-j9kg00qf 1648 23 phagocytosis phagocytosis NN cord-022526-j9kg00qf 1648 24 of of IN cord-022526-j9kg00qf 1648 25 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1648 26 by by IN cord-022526-j9kg00qf 1648 27 macrophages macrophage NNS cord-022526-j9kg00qf 1648 28 and and CC cord-022526-j9kg00qf 1648 29 neutrophils neutrophil NNS cord-022526-j9kg00qf 1648 30 . . . cord-022526-j9kg00qf 1649 1 29 29 CD cord-022526-j9kg00qf 1649 2 , , , cord-022526-j9kg00qf 1649 3 30 30 CD cord-022526-j9kg00qf 1649 4 Although although IN cord-022526-j9kg00qf 1649 5 phagocytosis phagocytosis NN cord-022526-j9kg00qf 1649 6 of of IN cord-022526-j9kg00qf 1649 7 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1649 8 is be VBZ cord-022526-j9kg00qf 1649 9 receptor receptor NN cord-022526-j9kg00qf 1649 10 dependent dependent JJ cord-022526-j9kg00qf 1649 11 , , , cord-022526-j9kg00qf 1649 12 it -PRON- PRP cord-022526-j9kg00qf 1649 13 appears appear VBZ cord-022526-j9kg00qf 1649 14 to to TO cord-022526-j9kg00qf 1649 15 be be VB cord-022526-j9kg00qf 1649 16 uncoupled uncouple VBN cord-022526-j9kg00qf 1649 17 from from IN cord-022526-j9kg00qf 1649 18 intracellular intracellular JJ cord-022526-j9kg00qf 1649 19 signaling signal VBG cord-022526-j9kg00qf 1649 20 events event NNS cord-022526-j9kg00qf 1649 21 and and CC cord-022526-j9kg00qf 1649 22 occurs occur VBZ cord-022526-j9kg00qf 1649 23 in in IN cord-022526-j9kg00qf 1649 24 the the DT cord-022526-j9kg00qf 1649 25 absence absence NN cord-022526-j9kg00qf 1649 26 of of IN cord-022526-j9kg00qf 1649 27 cell cell NN cord-022526-j9kg00qf 1649 28 activation activation NN cord-022526-j9kg00qf 1649 29 . . . cord-022526-j9kg00qf 1650 1 31 31 CD cord-022526-j9kg00qf 1650 2 LBP LBP NNP cord-022526-j9kg00qf 1650 3 further further RB cord-022526-j9kg00qf 1650 4 catalyzes catalyze VBZ cord-022526-j9kg00qf 1650 5 transfer transfer NN cord-022526-j9kg00qf 1650 6 of of IN cord-022526-j9kg00qf 1650 7 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1650 8 to to IN cord-022526-j9kg00qf 1650 9 lipoproteins lipoprotein NNS cord-022526-j9kg00qf 1650 10 such such JJ cord-022526-j9kg00qf 1650 11 as as IN cord-022526-j9kg00qf 1650 12 high high JJ cord-022526-j9kg00qf 1650 13 - - HYPH cord-022526-j9kg00qf 1650 14 density density NN cord-022526-j9kg00qf 1650 15 lipoprotein lipoprotein NN cord-022526-j9kg00qf 1650 16 , , , cord-022526-j9kg00qf 1650 17 which which WDT cord-022526-j9kg00qf 1650 18 neutralizes neutralize VBZ cord-022526-j9kg00qf 1650 19 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1650 20 activity activity NN cord-022526-j9kg00qf 1650 21 . . . cord-022526-j9kg00qf 1651 1 32 32 CD cord-022526-j9kg00qf 1652 1 This this DT cord-022526-j9kg00qf 1652 2 detoxifying detoxifying JJ cord-022526-j9kg00qf 1652 3 effect effect NN cord-022526-j9kg00qf 1652 4 may may MD cord-022526-j9kg00qf 1652 5 become become VB cord-022526-j9kg00qf 1652 6 important important JJ cord-022526-j9kg00qf 1652 7 when when WRB cord-022526-j9kg00qf 1652 8 large large JJ cord-022526-j9kg00qf 1652 9 amounts amount NNS cord-022526-j9kg00qf 1652 10 of of IN cord-022526-j9kg00qf 1652 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1652 12 are be VBP cord-022526-j9kg00qf 1652 13 present present JJ cord-022526-j9kg00qf 1652 14 . . . cord-022526-j9kg00qf 1653 1 A a DT cord-022526-j9kg00qf 1653 2 protective protective JJ cord-022526-j9kg00qf 1653 3 effect effect NN cord-022526-j9kg00qf 1653 4 of of IN cord-022526-j9kg00qf 1653 5 LBP LBP NNP cord-022526-j9kg00qf 1653 6 against against IN cord-022526-j9kg00qf 1653 7 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1653 8 challenge challenge NN cord-022526-j9kg00qf 1653 9 and and CC cord-022526-j9kg00qf 1653 10 infection infection NN cord-022526-j9kg00qf 1653 11 has have VBZ cord-022526-j9kg00qf 1653 12 been be VBN cord-022526-j9kg00qf 1653 13 demonstrated demonstrate VBN cord-022526-j9kg00qf 1653 14 in in IN cord-022526-j9kg00qf 1653 15 a a DT cord-022526-j9kg00qf 1653 16 murine murine JJ cord-022526-j9kg00qf 1653 17 model model NN cord-022526-j9kg00qf 1653 18 . . . cord-022526-j9kg00qf 1654 1 33 33 CD cord-022526-j9kg00qf 1654 2 The the DT cord-022526-j9kg00qf 1654 3 most most RBS cord-022526-j9kg00qf 1654 4 important important JJ cord-022526-j9kg00qf 1654 5 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1654 6 receptors receptor NNS cord-022526-j9kg00qf 1654 7 known know VBN cord-022526-j9kg00qf 1654 8 to to IN cord-022526-j9kg00qf 1654 9 date date NN cord-022526-j9kg00qf 1654 10 are be VBP cord-022526-j9kg00qf 1654 11 cluster cluster NN cord-022526-j9kg00qf 1654 12 differentiation differentiation NN cord-022526-j9kg00qf 1654 13 antigen antigen NN cord-022526-j9kg00qf 1654 14 14 14 CD cord-022526-j9kg00qf 1654 15 ( ( -LRB- cord-022526-j9kg00qf 1654 16 CD14 CD14 NNP cord-022526-j9kg00qf 1654 17 ) ) -RRB- cord-022526-j9kg00qf 1654 18 27 27 CD cord-022526-j9kg00qf 1654 19 and and CC cord-022526-j9kg00qf 1654 20 Toll Toll NNP cord-022526-j9kg00qf 1654 21 - - HYPH cord-022526-j9kg00qf 1654 22 like like JJ cord-022526-j9kg00qf 1654 23 receptor receptor NN cord-022526-j9kg00qf 1654 24 4 4 CD cord-022526-j9kg00qf 1654 25 ( ( -LRB- cord-022526-j9kg00qf 1654 26 TLR4 TLR4 NNP cord-022526-j9kg00qf 1654 27 ) ) -RRB- cord-022526-j9kg00qf 1654 28 . . . cord-022526-j9kg00qf 1655 1 34 34 LS cord-022526-j9kg00qf 1655 2 Both both DT cord-022526-j9kg00qf 1655 3 are be VBP cord-022526-j9kg00qf 1655 4 classified classify VBN cord-022526-j9kg00qf 1655 5 as as IN cord-022526-j9kg00qf 1655 6 pattern pattern NN cord-022526-j9kg00qf 1655 7 recognition recognition NN cord-022526-j9kg00qf 1655 8 receptors receptor NNS cord-022526-j9kg00qf 1655 9 , , , cord-022526-j9kg00qf 1655 10 35 35 CD cord-022526-j9kg00qf 1655 11 which which WDT cord-022526-j9kg00qf 1655 12 means mean VBZ cord-022526-j9kg00qf 1655 13 that that IN cord-022526-j9kg00qf 1655 14 they -PRON- PRP cord-022526-j9kg00qf 1655 15 recognize recognize VBP cord-022526-j9kg00qf 1655 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1655 17 as as IN cord-022526-j9kg00qf 1655 18 a a DT cord-022526-j9kg00qf 1655 19 pattern pattern NN cord-022526-j9kg00qf 1655 20 common common JJ cord-022526-j9kg00qf 1655 21 to to IN cord-022526-j9kg00qf 1655 22 all all DT cord-022526-j9kg00qf 1655 23 gram gram JJ cord-022526-j9kg00qf 1655 24 - - HYPH cord-022526-j9kg00qf 1655 25 negative negative JJ cord-022526-j9kg00qf 1655 26 bacteria bacteria NNS cord-022526-j9kg00qf 1655 27 . . . cord-022526-j9kg00qf 1656 1 CD14 CD14 NNP cord-022526-j9kg00qf 1656 2 is be VBZ cord-022526-j9kg00qf 1656 3 a a DT cord-022526-j9kg00qf 1656 4 53-kd 53-kd CD cord-022526-j9kg00qf 1656 5 protein protein NN cord-022526-j9kg00qf 1656 6 that that IN cord-022526-j9kg00qf 1656 7 in in IN cord-022526-j9kg00qf 1656 8 its -PRON- PRP$ cord-022526-j9kg00qf 1656 9 membrane membrane NN cord-022526-j9kg00qf 1656 10 - - HYPH cord-022526-j9kg00qf 1656 11 bound bind VBN cord-022526-j9kg00qf 1656 12 form form NN cord-022526-j9kg00qf 1656 13 ( ( -LRB- cord-022526-j9kg00qf 1656 14 mCD14 mCD14 NNP cord-022526-j9kg00qf 1656 15 ) ) -RRB- cord-022526-j9kg00qf 1656 16 is be VBZ cord-022526-j9kg00qf 1656 17 inserted insert VBN cord-022526-j9kg00qf 1656 18 into into IN cord-022526-j9kg00qf 1656 19 the the DT cord-022526-j9kg00qf 1656 20 cell cell NN cord-022526-j9kg00qf 1656 21 membrane membrane NN cord-022526-j9kg00qf 1656 22 via via IN cord-022526-j9kg00qf 1656 23 a a DT cord-022526-j9kg00qf 1656 24 glycosylphosphatidyl glycosylphosphatidyl NN cord-022526-j9kg00qf 1656 25 - - HYPH cord-022526-j9kg00qf 1656 26 inositol inositol JJ cord-022526-j9kg00qf 1656 27 anchor anchor NN cord-022526-j9kg00qf 1656 28 . . . cord-022526-j9kg00qf 1657 1 36 36 CD cord-022526-j9kg00qf 1657 2 CD14 CD14 NNP cord-022526-j9kg00qf 1657 3 is be VBZ cord-022526-j9kg00qf 1657 4 expressed express VBN cord-022526-j9kg00qf 1657 5 primarily primarily RB cord-022526-j9kg00qf 1657 6 on on IN cord-022526-j9kg00qf 1657 7 monocytes monocyte NNS cord-022526-j9kg00qf 1657 8 and and CC cord-022526-j9kg00qf 1657 9 tissue tissue NN cord-022526-j9kg00qf 1657 10 macrophages macrophage NNS cord-022526-j9kg00qf 1657 11 and and CC cord-022526-j9kg00qf 1657 12 to to IN cord-022526-j9kg00qf 1657 13 a a DT cord-022526-j9kg00qf 1657 14 lesser less JJR cord-022526-j9kg00qf 1657 15 extent extent NN cord-022526-j9kg00qf 1657 16 on on IN cord-022526-j9kg00qf 1657 17 neutrophils neutrophil NNS cord-022526-j9kg00qf 1657 18 . . . cord-022526-j9kg00qf 1658 1 37 37 CD cord-022526-j9kg00qf 1658 2 CD14 CD14 NNP cord-022526-j9kg00qf 1658 3 also also RB cord-022526-j9kg00qf 1658 4 is be VBZ cord-022526-j9kg00qf 1658 5 found find VBN cord-022526-j9kg00qf 1658 6 in in IN cord-022526-j9kg00qf 1658 7 a a DT cord-022526-j9kg00qf 1658 8 free free JJ cord-022526-j9kg00qf 1658 9 , , , cord-022526-j9kg00qf 1658 10 or or CC cord-022526-j9kg00qf 1658 11 soluble soluble JJ cord-022526-j9kg00qf 1658 12 , , , cord-022526-j9kg00qf 1658 13 form form NN cord-022526-j9kg00qf 1658 14 ( ( -LRB- cord-022526-j9kg00qf 1658 15 sCD14 scd14 NN cord-022526-j9kg00qf 1658 16 ) ) -RRB- cord-022526-j9kg00qf 1658 17 38 38 CD cord-022526-j9kg00qf 1658 18 that that WDT cord-022526-j9kg00qf 1658 19 can can MD cord-022526-j9kg00qf 1658 20 bind bind VB cord-022526-j9kg00qf 1658 21 to to IN cord-022526-j9kg00qf 1658 22 cell cell NN cord-022526-j9kg00qf 1658 23 types type NNS cord-022526-j9kg00qf 1658 24 lacking lack VBG cord-022526-j9kg00qf 1658 25 CD14 CD14 NNP cord-022526-j9kg00qf 1658 26 , , , cord-022526-j9kg00qf 1658 27 such such JJ cord-022526-j9kg00qf 1658 28 as as IN cord-022526-j9kg00qf 1658 29 endothelial endothelial JJ cord-022526-j9kg00qf 1658 30 cells cell NNS cord-022526-j9kg00qf 1658 31 , , , cord-022526-j9kg00qf 1658 32 and and CC cord-022526-j9kg00qf 1658 33 make make VB cord-022526-j9kg00qf 1658 34 them -PRON- PRP cord-022526-j9kg00qf 1658 35 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1658 36 - - HYPH cord-022526-j9kg00qf 1658 37 responsive responsive JJ cord-022526-j9kg00qf 1658 38 . . . cord-022526-j9kg00qf 1659 1 In in IN cord-022526-j9kg00qf 1659 2 addition addition NN cord-022526-j9kg00qf 1659 3 to to IN cord-022526-j9kg00qf 1659 4 this this DT cord-022526-j9kg00qf 1659 5 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 1659 6 effect effect NN cord-022526-j9kg00qf 1659 7 , , , cord-022526-j9kg00qf 1659 8 high high JJ cord-022526-j9kg00qf 1659 9 concentrations concentration NNS cord-022526-j9kg00qf 1659 10 of of IN cord-022526-j9kg00qf 1659 11 sCD14 scd14 NN cord-022526-j9kg00qf 1659 12 can can MD cord-022526-j9kg00qf 1659 13 sequester sequester VB cord-022526-j9kg00qf 1659 14 and and CC cord-022526-j9kg00qf 1659 15 neutralize neutralize VB cord-022526-j9kg00qf 1659 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1659 17 . . . cord-022526-j9kg00qf 1660 1 39 39 CD cord-022526-j9kg00qf 1661 1 The the DT cord-022526-j9kg00qf 1661 2 amount amount NN cord-022526-j9kg00qf 1661 3 of of IN cord-022526-j9kg00qf 1661 4 circulating circulate VBG cord-022526-j9kg00qf 1661 5 sCD14 sCD14 NNP cord-022526-j9kg00qf 1661 6 greatly greatly RB cord-022526-j9kg00qf 1661 7 increases increase VBZ cord-022526-j9kg00qf 1661 8 during during IN cord-022526-j9kg00qf 1661 9 inflammation inflammation NN cord-022526-j9kg00qf 1661 10 , , , cord-022526-j9kg00qf 1661 11 which which WDT cord-022526-j9kg00qf 1661 12 makes make VBZ cord-022526-j9kg00qf 1661 13 it -PRON- PRP cord-022526-j9kg00qf 1661 14 a a DT cord-022526-j9kg00qf 1661 15 useful useful JJ cord-022526-j9kg00qf 1661 16 marker marker NN cord-022526-j9kg00qf 1661 17 of of IN cord-022526-j9kg00qf 1661 18 acute acute JJ cord-022526-j9kg00qf 1661 19 and and CC cord-022526-j9kg00qf 1661 20 chronic chronic JJ cord-022526-j9kg00qf 1661 21 inflammation inflammation NN cord-022526-j9kg00qf 1661 22 . . . cord-022526-j9kg00qf 1662 1 37 37 CD cord-022526-j9kg00qf 1663 1 Although although IN cord-022526-j9kg00qf 1663 2 CD14 CD14 NNP cord-022526-j9kg00qf 1663 3 is be VBZ cord-022526-j9kg00qf 1663 4 known know VBN cord-022526-j9kg00qf 1663 5 to to TO cord-022526-j9kg00qf 1663 6 be be VB cord-022526-j9kg00qf 1663 7 crucial crucial JJ cord-022526-j9kg00qf 1663 8 for for IN cord-022526-j9kg00qf 1663 9 cellular cellular JJ cord-022526-j9kg00qf 1663 10 activation activation NN cord-022526-j9kg00qf 1663 11 , , , cord-022526-j9kg00qf 1663 12 it -PRON- PRP cord-022526-j9kg00qf 1663 13 can can MD cord-022526-j9kg00qf 1663 14 not not RB cord-022526-j9kg00qf 1663 15 transmit transmit VB cord-022526-j9kg00qf 1663 16 signals signal NNS cord-022526-j9kg00qf 1663 17 to to IN cord-022526-j9kg00qf 1663 18 the the DT cord-022526-j9kg00qf 1663 19 inside inside NN cord-022526-j9kg00qf 1663 20 of of IN cord-022526-j9kg00qf 1663 21 the the DT cord-022526-j9kg00qf 1663 22 cell cell NN cord-022526-j9kg00qf 1663 23 because because IN cord-022526-j9kg00qf 1663 24 it -PRON- PRP cord-022526-j9kg00qf 1663 25 lacks lack VBZ cord-022526-j9kg00qf 1663 26 a a DT cord-022526-j9kg00qf 1663 27 transmembrane transmembrane NN cord-022526-j9kg00qf 1663 28 domain domain NN cord-022526-j9kg00qf 1663 29 . . . cord-022526-j9kg00qf 1664 1 The the DT cord-022526-j9kg00qf 1664 2 missing missing JJ cord-022526-j9kg00qf 1664 3 link link NN cord-022526-j9kg00qf 1664 4 between between IN cord-022526-j9kg00qf 1664 5 CD14 CD14 NNP cord-022526-j9kg00qf 1664 6 and and CC cord-022526-j9kg00qf 1664 7 the the DT cord-022526-j9kg00qf 1664 8 cytosolic cytosolic JJ cord-022526-j9kg00qf 1664 9 environment environment NN cord-022526-j9kg00qf 1664 10 is be VBZ cord-022526-j9kg00qf 1664 11 a a DT cord-022526-j9kg00qf 1664 12 Toll Toll NNP cord-022526-j9kg00qf 1664 13 - - HYPH cord-022526-j9kg00qf 1664 14 like like JJ cord-022526-j9kg00qf 1664 15 receptor receptor NN cord-022526-j9kg00qf 1664 16 in in IN cord-022526-j9kg00qf 1664 17 association association NN cord-022526-j9kg00qf 1664 18 with with IN cord-022526-j9kg00qf 1664 19 a a DT cord-022526-j9kg00qf 1664 20 molecule molecule NN cord-022526-j9kg00qf 1664 21 named name VBN cord-022526-j9kg00qf 1664 22 MD-2 MD-2 NNP cord-022526-j9kg00qf 1664 23 . . . cord-022526-j9kg00qf 1665 1 40 40 CD cord-022526-j9kg00qf 1666 1 The the DT cord-022526-j9kg00qf 1666 2 name name NN cord-022526-j9kg00qf 1666 3 Toll Toll NNP cord-022526-j9kg00qf 1666 4 - - HYPH cord-022526-j9kg00qf 1666 5 like like JJ cord-022526-j9kg00qf 1666 6 receptor receptor NN cord-022526-j9kg00qf 1666 7 stems stem VBZ cord-022526-j9kg00qf 1666 8 from from IN cord-022526-j9kg00qf 1666 9 the the DT cord-022526-j9kg00qf 1666 10 homology homology NN cord-022526-j9kg00qf 1666 11 of of IN cord-022526-j9kg00qf 1666 12 the the DT cord-022526-j9kg00qf 1666 13 mammalian mammalian JJ cord-022526-j9kg00qf 1666 14 receptor receptor NN cord-022526-j9kg00qf 1666 15 with with IN cord-022526-j9kg00qf 1666 16 a a DT cord-022526-j9kg00qf 1666 17 receptor receptor NN cord-022526-j9kg00qf 1666 18 type type NN cord-022526-j9kg00qf 1666 19 in in IN cord-022526-j9kg00qf 1666 20 Drosophila Drosophila NNP cord-022526-j9kg00qf 1666 21 ( ( -LRB- cord-022526-j9kg00qf 1666 22 Toll toll NN cord-022526-j9kg00qf 1666 23 ) ) -RRB- cord-022526-j9kg00qf 1666 24 that that WDT cord-022526-j9kg00qf 1666 25 is be VBZ cord-022526-j9kg00qf 1666 26 important important JJ cord-022526-j9kg00qf 1666 27 for for IN cord-022526-j9kg00qf 1666 28 dorsoventral dorsoventral JJ cord-022526-j9kg00qf 1666 29 orientation orientation NN cord-022526-j9kg00qf 1666 30 and and CC cord-022526-j9kg00qf 1666 31 immune immune JJ cord-022526-j9kg00qf 1666 32 responses response NNS cord-022526-j9kg00qf 1666 33 in in IN cord-022526-j9kg00qf 1666 34 the the DT cord-022526-j9kg00qf 1666 35 fly fly NN cord-022526-j9kg00qf 1666 36 . . . cord-022526-j9kg00qf 1667 1 A a DT cord-022526-j9kg00qf 1667 2 number number NN cord-022526-j9kg00qf 1667 3 of of IN cord-022526-j9kg00qf 1667 4 Toll toll NN cord-022526-j9kg00qf 1667 5 - - HYPH cord-022526-j9kg00qf 1667 6 like like JJ cord-022526-j9kg00qf 1667 7 receptors receptor NNS cord-022526-j9kg00qf 1667 8 have have VBP cord-022526-j9kg00qf 1667 9 been be VBN cord-022526-j9kg00qf 1667 10 identified identify VBN cord-022526-j9kg00qf 1667 11 in in IN cord-022526-j9kg00qf 1667 12 mammalian mammalian JJ cord-022526-j9kg00qf 1667 13 species specie NNS cord-022526-j9kg00qf 1667 14 so so RB cord-022526-j9kg00qf 1667 15 far far RB cord-022526-j9kg00qf 1667 16 , , , cord-022526-j9kg00qf 1667 17 but but CC cord-022526-j9kg00qf 1667 18 TLR4 TLR4 NNP cord-022526-j9kg00qf 1667 19 appears appear VBZ cord-022526-j9kg00qf 1667 20 to to TO cord-022526-j9kg00qf 1667 21 be be VB cord-022526-j9kg00qf 1667 22 the the DT cord-022526-j9kg00qf 1667 23 receptor receptor NN cord-022526-j9kg00qf 1667 24 subtype subtype NN cord-022526-j9kg00qf 1667 25 most most RBS cord-022526-j9kg00qf 1667 26 important important JJ cord-022526-j9kg00qf 1667 27 for for IN cord-022526-j9kg00qf 1667 28 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1667 29 signaling signaling NN cord-022526-j9kg00qf 1667 30 . . . cord-022526-j9kg00qf 1668 1 34 34 CD cord-022526-j9kg00qf 1669 1 The the DT cord-022526-j9kg00qf 1669 2 importance importance NN cord-022526-j9kg00qf 1669 3 of of IN cord-022526-j9kg00qf 1669 4 CD14 CD14 NNP cord-022526-j9kg00qf 1669 5 and and CC cord-022526-j9kg00qf 1669 6 TLR4 TLR4 NNP cord-022526-j9kg00qf 1669 7 in in IN cord-022526-j9kg00qf 1669 8 the the DT cord-022526-j9kg00qf 1669 9 cellular cellular JJ cord-022526-j9kg00qf 1669 10 response response NN cord-022526-j9kg00qf 1669 11 to to IN cord-022526-j9kg00qf 1669 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1669 13 has have VBZ cord-022526-j9kg00qf 1669 14 been be VBN cord-022526-j9kg00qf 1669 15 demonstrated demonstrate VBN cord-022526-j9kg00qf 1669 16 in in IN cord-022526-j9kg00qf 1669 17 a a DT cord-022526-j9kg00qf 1669 18 number number NN cord-022526-j9kg00qf 1669 19 of of IN cord-022526-j9kg00qf 1669 20 experiments experiment NNS cord-022526-j9kg00qf 1669 21 . . . cord-022526-j9kg00qf 1670 1 Mice mouse NNS cord-022526-j9kg00qf 1670 2 deficient deficient JJ cord-022526-j9kg00qf 1670 3 in in IN cord-022526-j9kg00qf 1670 4 CD14 CD14 NNP cord-022526-j9kg00qf 1670 5 are be VBP cord-022526-j9kg00qf 1670 6 incapable incapable JJ cord-022526-j9kg00qf 1670 7 of of IN cord-022526-j9kg00qf 1670 8 mounting mount VBG cord-022526-j9kg00qf 1670 9 a a DT cord-022526-j9kg00qf 1670 10 normal normal JJ cord-022526-j9kg00qf 1670 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 1670 12 response response NN cord-022526-j9kg00qf 1670 13 to to IN cord-022526-j9kg00qf 1670 14 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1670 15 , , , cord-022526-j9kg00qf 1670 16 39 39 CD cord-022526-j9kg00qf 1670 17 whereas whereas IN cord-022526-j9kg00qf 1670 18 mutation mutation NN cord-022526-j9kg00qf 1670 19 or or CC cord-022526-j9kg00qf 1670 20 deletion deletion NN cord-022526-j9kg00qf 1670 21 of of IN cord-022526-j9kg00qf 1670 22 the the DT cord-022526-j9kg00qf 1670 23 gene gene NN cord-022526-j9kg00qf 1670 24 encoding encoding NN cord-022526-j9kg00qf 1670 25 for for IN cord-022526-j9kg00qf 1670 26 TLR4 TLR4 NNP cord-022526-j9kg00qf 1670 27 causes cause VBZ cord-022526-j9kg00qf 1670 28 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1670 29 hyporesponsiveness hyporesponsiveness NN cord-022526-j9kg00qf 1670 30 . . . cord-022526-j9kg00qf 1671 1 [ [ -LRB- cord-022526-j9kg00qf 1671 2 41 41 CD cord-022526-j9kg00qf 1671 3 ] ] -RRB- cord-022526-j9kg00qf 1671 4 [ [ -LRB- cord-022526-j9kg00qf 1671 5 42 42 CD cord-022526-j9kg00qf 1671 6 ] ] -RRB- cord-022526-j9kg00qf 1672 1 [ [ -LRB- cord-022526-j9kg00qf 1672 2 43 43 CD cord-022526-j9kg00qf 1672 3 ] ] -RRB- cord-022526-j9kg00qf 1673 1 After after IN cord-022526-j9kg00qf 1673 2 binding bind VBG cord-022526-j9kg00qf 1673 3 of of IN cord-022526-j9kg00qf 1673 4 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1673 5 to to IN cord-022526-j9kg00qf 1673 6 cellular cellular JJ cord-022526-j9kg00qf 1673 7 receptors receptor NNS cord-022526-j9kg00qf 1673 8 , , , cord-022526-j9kg00qf 1673 9 a a DT cord-022526-j9kg00qf 1673 10 multitude multitude NN cord-022526-j9kg00qf 1673 11 of of IN cord-022526-j9kg00qf 1673 12 signaling signal VBG cord-022526-j9kg00qf 1673 13 events event NNS cord-022526-j9kg00qf 1673 14 takes take VBZ cord-022526-j9kg00qf 1673 15 place place NN cord-022526-j9kg00qf 1673 16 within within IN cord-022526-j9kg00qf 1673 17 the the DT cord-022526-j9kg00qf 1673 18 cell cell NN cord-022526-j9kg00qf 1673 19 and and CC cord-022526-j9kg00qf 1673 20 results result NNS cord-022526-j9kg00qf 1673 21 in in IN cord-022526-j9kg00qf 1673 22 the the DT cord-022526-j9kg00qf 1673 23 alterations alteration NNS cord-022526-j9kg00qf 1673 24 of of IN cord-022526-j9kg00qf 1673 25 cellular cellular JJ cord-022526-j9kg00qf 1673 26 metabolism metabolism NN cord-022526-j9kg00qf 1673 27 known know VBN cord-022526-j9kg00qf 1673 28 as as IN cord-022526-j9kg00qf 1673 29 cell cell NN cord-022526-j9kg00qf 1673 30 activation activation NN cord-022526-j9kg00qf 1673 31 . . . cord-022526-j9kg00qf 1674 1 Signaling signal VBG cord-022526-j9kg00qf 1674 2 pathways pathway NNS cord-022526-j9kg00qf 1674 3 are be VBP cord-022526-j9kg00qf 1674 4 characterized characterize VBN cord-022526-j9kg00qf 1674 5 by by IN cord-022526-j9kg00qf 1674 6 sequential sequential JJ cord-022526-j9kg00qf 1674 7 phosphorylation phosphorylation NN cord-022526-j9kg00qf 1674 8 and and CC cord-022526-j9kg00qf 1674 9 thereby thereby RB cord-022526-j9kg00qf 1674 10 activation activation NN cord-022526-j9kg00qf 1674 11 of of IN cord-022526-j9kg00qf 1674 12 enzymatic enzymatic JJ cord-022526-j9kg00qf 1674 13 activities activity NNS cord-022526-j9kg00qf 1674 14 . . . cord-022526-j9kg00qf 1675 1 A a DT cord-022526-j9kg00qf 1675 2 typical typical JJ cord-022526-j9kg00qf 1675 3 end end NN cord-022526-j9kg00qf 1675 4 result result NN cord-022526-j9kg00qf 1675 5 of of IN cord-022526-j9kg00qf 1675 6 intracellular intracellular JJ cord-022526-j9kg00qf 1675 7 signaling signaling NN cord-022526-j9kg00qf 1675 8 is be VBZ cord-022526-j9kg00qf 1675 9 the the DT cord-022526-j9kg00qf 1675 10 activation activation NN cord-022526-j9kg00qf 1675 11 of of IN cord-022526-j9kg00qf 1675 12 transcription transcription NN cord-022526-j9kg00qf 1675 13 factors factor NNS cord-022526-j9kg00qf 1675 14 ; ; : cord-022526-j9kg00qf 1675 15 for for IN cord-022526-j9kg00qf 1675 16 example example NN cord-022526-j9kg00qf 1675 17 , , , cord-022526-j9kg00qf 1675 18 proteins protein NNS cord-022526-j9kg00qf 1675 19 that that WDT cord-022526-j9kg00qf 1675 20 bind bind VBP cord-022526-j9kg00qf 1675 21 to to IN cord-022526-j9kg00qf 1675 22 DNA DNA NNP cord-022526-j9kg00qf 1675 23 and and CC cord-022526-j9kg00qf 1675 24 promote promote VB cord-022526-j9kg00qf 1675 25 gene gene NN cord-022526-j9kg00qf 1675 26 transcription transcription NN cord-022526-j9kg00qf 1675 27 . . . cord-022526-j9kg00qf 1676 1 Translational translational JJ cord-022526-j9kg00qf 1676 2 mechanisms mechanism NNS cord-022526-j9kg00qf 1676 3 are be VBP cord-022526-j9kg00qf 1676 4 activated activate VBN cord-022526-j9kg00qf 1676 5 in in IN cord-022526-j9kg00qf 1676 6 a a DT cord-022526-j9kg00qf 1676 7 similar similar JJ cord-022526-j9kg00qf 1676 8 manner manner NN cord-022526-j9kg00qf 1676 9 . . . cord-022526-j9kg00qf 1677 1 Among among IN cord-022526-j9kg00qf 1677 2 the the DT cord-022526-j9kg00qf 1677 3 bestcharacterized bestcharacterized JJ cord-022526-j9kg00qf 1677 4 pathways pathway NNS cord-022526-j9kg00qf 1677 5 in in IN cord-022526-j9kg00qf 1677 6 endotoxin endotoxin NN cord-022526-j9kg00qf 1677 7 - - HYPH cord-022526-j9kg00qf 1677 8 induced induce VBN cord-022526-j9kg00qf 1677 9 cell cell NN cord-022526-j9kg00qf 1677 10 signaling signal VBG cord-022526-j9kg00qf 1677 11 are be VBP cord-022526-j9kg00qf 1677 12 the the DT cord-022526-j9kg00qf 1677 13 mitogen mitogen NN cord-022526-j9kg00qf 1677 14 - - HYPH cord-022526-j9kg00qf 1677 15 activated activate VBN cord-022526-j9kg00qf 1677 16 protein protein NN cord-022526-j9kg00qf 1677 17 kinase kinase NN cord-022526-j9kg00qf 1677 18 ( ( -LRB- cord-022526-j9kg00qf 1677 19 MAPK MAPK NNP cord-022526-j9kg00qf 1677 20 ) ) -RRB- cord-022526-j9kg00qf 1677 21 pathways pathway NNS cord-022526-j9kg00qf 1677 22 and and CC cord-022526-j9kg00qf 1677 23 the the DT cord-022526-j9kg00qf 1677 24 activation activation NN cord-022526-j9kg00qf 1677 25 of of IN cord-022526-j9kg00qf 1677 26 transcription transcription NN cord-022526-j9kg00qf 1677 27 factor factor NN cord-022526-j9kg00qf 1677 28 nuclear nuclear JJ cord-022526-j9kg00qf 1677 29 factor factor NN cord-022526-j9kg00qf 1677 30 κB κB . cord-022526-j9kg00qf 1678 1 ( ( -LRB- cord-022526-j9kg00qf 1678 2 NFκB NFκB NNP cord-022526-j9kg00qf 1678 3 ) ) -RRB- cord-022526-j9kg00qf 1679 1 ( ( -LRB- cord-022526-j9kg00qf 1679 2 Figure figure NN cord-022526-j9kg00qf 1679 3 13.7 13.7 CD cord-022526-j9kg00qf 1679 4 - - SYM cord-022526-j9kg00qf 1679 5 4 4 CD cord-022526-j9kg00qf 1679 6 ) ) -RRB- cord-022526-j9kg00qf 1679 7 . . . cord-022526-j9kg00qf 1680 1 44 44 CD cord-022526-j9kg00qf 1680 2 , , , cord-022526-j9kg00qf 1680 3 45 45 CD cord-022526-j9kg00qf 1681 1 In in IN cord-022526-j9kg00qf 1681 2 the the DT cord-022526-j9kg00qf 1681 3 NFκB NFκB NNP cord-022526-j9kg00qf 1681 4 pathway pathway NN cord-022526-j9kg00qf 1681 5 the the DT cord-022526-j9kg00qf 1681 6 intracellular intracellular JJ cord-022526-j9kg00qf 1681 7 domain domain NN cord-022526-j9kg00qf 1681 8 of of IN cord-022526-j9kg00qf 1681 9 TLR4 TLR4 NNP cord-022526-j9kg00qf 1681 10 associates associate NNS cord-022526-j9kg00qf 1681 11 with with IN cord-022526-j9kg00qf 1681 12 the the DT cord-022526-j9kg00qf 1681 13 adapter adapter NN cord-022526-j9kg00qf 1681 14 protein protein NN cord-022526-j9kg00qf 1681 15 myeloid myeloid NN cord-022526-j9kg00qf 1681 16 differentiation differentiation NN cord-022526-j9kg00qf 1681 17 factor factor NN cord-022526-j9kg00qf 1681 18 88 88 CD cord-022526-j9kg00qf 1681 19 and and CC cord-022526-j9kg00qf 1681 20 recruits recruit VBZ cord-022526-j9kg00qf 1681 21 interleukin-1 interleukin-1 NNP cord-022526-j9kg00qf 1681 22 receptor receptor NN cord-022526-j9kg00qf 1681 23 - - HYPH cord-022526-j9kg00qf 1681 24 associated associate VBN cord-022526-j9kg00qf 1681 25 kinase kinase NN cord-022526-j9kg00qf 1681 26 to to IN cord-022526-j9kg00qf 1681 27 the the DT cord-022526-j9kg00qf 1681 28 complex complex NN cord-022526-j9kg00qf 1681 29 . . . cord-022526-j9kg00qf 1682 1 Activation activation NN cord-022526-j9kg00qf 1682 2 of of IN cord-022526-j9kg00qf 1682 3 interleukin-1 interleukin-1 NNP cord-022526-j9kg00qf 1682 4 receptor receptor NN cord-022526-j9kg00qf 1682 5 - - HYPH cord-022526-j9kg00qf 1682 6 associated associate VBN cord-022526-j9kg00qf 1682 7 kinase kinase NN cord-022526-j9kg00qf 1682 8 , , , cord-022526-j9kg00qf 1682 9 tumor tumor NN cord-022526-j9kg00qf 1682 10 necrosis necrosis NN cord-022526-j9kg00qf 1682 11 factor factor NN cord-022526-j9kg00qf 1682 12 receptor receptor NN cord-022526-j9kg00qf 1682 13 - - HYPH cord-022526-j9kg00qf 1682 14 associated associate VBN cord-022526-j9kg00qf 1682 15 factor factor NN cord-022526-j9kg00qf 1682 16 , , , cord-022526-j9kg00qf 1682 17 NFκB NFκB NNP cord-022526-j9kg00qf 1682 18 - - HYPH cord-022526-j9kg00qf 1682 19 inducing induce VBG cord-022526-j9kg00qf 1682 20 kinase kinase NN cord-022526-j9kg00qf 1682 21 , , , cord-022526-j9kg00qf 1682 22 and and CC cord-022526-j9kg00qf 1682 23 IκB iκb NN cord-022526-j9kg00qf 1682 24 - - HYPH cord-022526-j9kg00qf 1682 25 kinase kinase NN cord-022526-j9kg00qf 1682 26 follow follow VBP cord-022526-j9kg00qf 1682 27 , , , cord-022526-j9kg00qf 1682 28 and and CC cord-022526-j9kg00qf 1682 29 lastly lastly RB cord-022526-j9kg00qf 1682 30 , , , cord-022526-j9kg00qf 1682 31 IκB IκB NNP cord-022526-j9kg00qf 1682 32 is be VBZ cord-022526-j9kg00qf 1682 33 phosphorylated phosphorylate VBN cord-022526-j9kg00qf 1682 34 . . . cord-022526-j9kg00qf 1683 1 IκB IκB NNP cord-022526-j9kg00qf 1683 2 is be VBZ cord-022526-j9kg00qf 1683 3 an an DT cord-022526-j9kg00qf 1683 4 inhibitor inhibitor NN cord-022526-j9kg00qf 1683 5 protein protein NN cord-022526-j9kg00qf 1683 6 complex complex NN cord-022526-j9kg00qf 1683 7 that that WDT cord-022526-j9kg00qf 1683 8 sequesters sequester VBZ cord-022526-j9kg00qf 1683 9 and and CC cord-022526-j9kg00qf 1683 10 inactivates inactivate VBZ cord-022526-j9kg00qf 1683 11 NFκB NFκB NNP cord-022526-j9kg00qf 1683 12 in in IN cord-022526-j9kg00qf 1683 13 the the DT cord-022526-j9kg00qf 1683 14 cytoplasm cytoplasm NN cord-022526-j9kg00qf 1683 15 . . . cord-022526-j9kg00qf 1684 1 On on IN cord-022526-j9kg00qf 1684 2 phosphorylation phosphorylation NN cord-022526-j9kg00qf 1684 3 , , , cord-022526-j9kg00qf 1684 4 IκB iκb NN cord-022526-j9kg00qf 1684 5 is be VBZ cord-022526-j9kg00qf 1684 6 ubiquinated ubiquinate VBN cord-022526-j9kg00qf 1684 7 and and CC cord-022526-j9kg00qf 1684 8 degraded degrade VBN cord-022526-j9kg00qf 1684 9 , , , cord-022526-j9kg00qf 1684 10 and and CC cord-022526-j9kg00qf 1684 11 NFκB NFκB NNP cord-022526-j9kg00qf 1684 12 is be VBZ cord-022526-j9kg00qf 1684 13 translocated translocate VBN cord-022526-j9kg00qf 1684 14 to to IN cord-022526-j9kg00qf 1684 15 the the DT cord-022526-j9kg00qf 1684 16 nucleus nucleus NN cord-022526-j9kg00qf 1684 17 where where WRB cord-022526-j9kg00qf 1684 18 it -PRON- PRP cord-022526-j9kg00qf 1684 19 unfolds unfold VBZ cord-022526-j9kg00qf 1684 20 its -PRON- PRP$ cord-022526-j9kg00qf 1684 21 activity activity NN cord-022526-j9kg00qf 1684 22 . . . cord-022526-j9kg00qf 1685 1 46 46 CD cord-022526-j9kg00qf 1686 1 NFκB NFκB NNP cord-022526-j9kg00qf 1686 2 is be VBZ cord-022526-j9kg00qf 1686 3 a a DT cord-022526-j9kg00qf 1686 4 dimeric dimeric JJ cord-022526-j9kg00qf 1686 5 protein protein NN cord-022526-j9kg00qf 1686 6 complex complex NN cord-022526-j9kg00qf 1686 7 with with IN cord-022526-j9kg00qf 1686 8 several several JJ cord-022526-j9kg00qf 1686 9 isoforms isoform NNS cord-022526-j9kg00qf 1686 10 of of IN cord-022526-j9kg00qf 1686 11 which which WDT cord-022526-j9kg00qf 1686 12 the the DT cord-022526-j9kg00qf 1686 13 p65 p65 CD cord-022526-j9kg00qf 1686 14 / / SYM cord-022526-j9kg00qf 1686 15 p50 p50 NN cord-022526-j9kg00qf 1686 16 heterodimer heterodimer NN cord-022526-j9kg00qf 1686 17 is be VBZ cord-022526-j9kg00qf 1686 18 the the DT cord-022526-j9kg00qf 1686 19 most most RBS cord-022526-j9kg00qf 1686 20 important important JJ cord-022526-j9kg00qf 1686 21 inducible inducible JJ cord-022526-j9kg00qf 1686 22 complex complex NN cord-022526-j9kg00qf 1686 23 in in IN cord-022526-j9kg00qf 1686 24 mammals mammal NNS cord-022526-j9kg00qf 1686 25 . . . cord-022526-j9kg00qf 1687 1 47 47 CD cord-022526-j9kg00qf 1687 2 Proteins protein NNS cord-022526-j9kg00qf 1687 3 of of IN cord-022526-j9kg00qf 1687 4 importance importance NN cord-022526-j9kg00qf 1687 5 for for IN cord-022526-j9kg00qf 1687 6 the the DT cord-022526-j9kg00qf 1687 7 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1687 8 of of IN cord-022526-j9kg00qf 1687 9 septic septic JJ cord-022526-j9kg00qf 1687 10 shock shock NN cord-022526-j9kg00qf 1688 1 , , , cord-022526-j9kg00qf 1688 2 the the DT cord-022526-j9kg00qf 1688 3 genes gene NNS cord-022526-j9kg00qf 1688 4 of of IN cord-022526-j9kg00qf 1688 5 which which WDT cord-022526-j9kg00qf 1688 6 contain contain VBP cord-022526-j9kg00qf 1688 7 promoter promoter NN cord-022526-j9kg00qf 1688 8 elements element NNS cord-022526-j9kg00qf 1688 9 for for IN cord-022526-j9kg00qf 1688 10 NFκB NFκB NNP cord-022526-j9kg00qf 1688 11 , , , cord-022526-j9kg00qf 1688 12 include include VBP cord-022526-j9kg00qf 1688 13 cytokines cytokine NNS cord-022526-j9kg00qf 1688 14 , , , cord-022526-j9kg00qf 1688 15 inducible inducible JJ cord-022526-j9kg00qf 1688 16 nitric nitric NN cord-022526-j9kg00qf 1688 17 oxide oxide NN cord-022526-j9kg00qf 1688 18 synthase synthase NN cord-022526-j9kg00qf 1688 19 , , , cord-022526-j9kg00qf 1688 20 and and CC cord-022526-j9kg00qf 1688 21 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 1688 22 2 2 CD cord-022526-j9kg00qf 1688 23 ( ( -LRB- cord-022526-j9kg00qf 1688 24 COX-2 COX-2 NNP cord-022526-j9kg00qf 1688 25 ) ) -RRB- cord-022526-j9kg00qf 1688 26 . . . cord-022526-j9kg00qf 1689 1 44 44 CD cord-022526-j9kg00qf 1690 1 Three three CD cord-022526-j9kg00qf 1690 2 groups group NNS cord-022526-j9kg00qf 1690 3 of of IN cord-022526-j9kg00qf 1690 4 MAPKs mapk NNS cord-022526-j9kg00qf 1690 5 known know VBN cord-022526-j9kg00qf 1690 6 to to TO cord-022526-j9kg00qf 1690 7 be be VB cord-022526-j9kg00qf 1690 8 crucially crucially RB cord-022526-j9kg00qf 1690 9 important important JJ cord-022526-j9kg00qf 1690 10 for for IN cord-022526-j9kg00qf 1690 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1690 12 - - HYPH cord-022526-j9kg00qf 1690 13 induced induce VBN cord-022526-j9kg00qf 1690 14 signal signal NN cord-022526-j9kg00qf 1690 15 transduction transduction NN cord-022526-j9kg00qf 1690 16 are be VBP cord-022526-j9kg00qf 1690 17 extracellular extracellular JJ cord-022526-j9kg00qf 1690 18 signal signal NN cord-022526-j9kg00qf 1690 19 - - HYPH cord-022526-j9kg00qf 1690 20 regulated regulate VBN cord-022526-j9kg00qf 1690 21 kinase kinase NN cord-022526-j9kg00qf 1690 22 , , , cord-022526-j9kg00qf 1690 23 c c NN cord-022526-j9kg00qf 1690 24 - - : cord-022526-j9kg00qf 1690 25 Jun Jun NNP cord-022526-j9kg00qf 1690 26 - - HYPH cord-022526-j9kg00qf 1690 27 terminal terminal JJ cord-022526-j9kg00qf 1690 28 kinase kinase NN cord-022526-j9kg00qf 1690 29 , , , cord-022526-j9kg00qf 1690 30 and and CC cord-022526-j9kg00qf 1690 31 p38 p38 NN cord-022526-j9kg00qf 1690 32 . . . cord-022526-j9kg00qf 1691 1 Final final JJ cord-022526-j9kg00qf 1691 2 effects effect NNS cord-022526-j9kg00qf 1691 3 of of IN cord-022526-j9kg00qf 1691 4 signaling signal VBG cord-022526-j9kg00qf 1691 5 through through IN cord-022526-j9kg00qf 1691 6 MAPK MAPK NNP cord-022526-j9kg00qf 1691 7 pathways pathway NNS cord-022526-j9kg00qf 1691 8 include include VBP cord-022526-j9kg00qf 1691 9 the the DT cord-022526-j9kg00qf 1691 10 activation activation NN cord-022526-j9kg00qf 1691 11 of of IN cord-022526-j9kg00qf 1691 12 several several JJ cord-022526-j9kg00qf 1691 13 transcription transcription NN cord-022526-j9kg00qf 1691 14 factors factor NNS cord-022526-j9kg00qf 1691 15 , , , cord-022526-j9kg00qf 1691 16 translation translation NN cord-022526-j9kg00qf 1691 17 initiation initiation NN cord-022526-j9kg00qf 1691 18 factors factor NNS cord-022526-j9kg00qf 1691 19 , , , cord-022526-j9kg00qf 1691 20 and and CC cord-022526-j9kg00qf 1691 21 cytosolic cytosolic JJ cord-022526-j9kg00qf 1691 22 enzymes enzyme NNS cord-022526-j9kg00qf 1691 23 such such JJ cord-022526-j9kg00qf 1691 24 as as IN cord-022526-j9kg00qf 1691 25 phospholipase phospholipase NN cord-022526-j9kg00qf 1691 26 A a DT cord-022526-j9kg00qf 1691 27 2 2 CD cord-022526-j9kg00qf 1691 28 , , , cord-022526-j9kg00qf 1691 29 as as RB cord-022526-j9kg00qf 1691 30 well well RB cord-022526-j9kg00qf 1691 31 as as IN cord-022526-j9kg00qf 1691 32 an an DT cord-022526-j9kg00qf 1691 33 increase increase NN cord-022526-j9kg00qf 1691 34 in in IN cord-022526-j9kg00qf 1691 35 the the DT cord-022526-j9kg00qf 1691 36 expression expression NN cord-022526-j9kg00qf 1691 37 of of IN cord-022526-j9kg00qf 1691 38 adhesion adhesion NN cord-022526-j9kg00qf 1691 39 molecules molecule NNS cord-022526-j9kg00qf 1691 40 on on IN cord-022526-j9kg00qf 1691 41 the the DT cord-022526-j9kg00qf 1691 42 cell cell NN cord-022526-j9kg00qf 1691 43 surface surface NN cord-022526-j9kg00qf 1691 44 . . . cord-022526-j9kg00qf 1692 1 44 44 CD cord-022526-j9kg00qf 1693 1 Despite despite IN cord-022526-j9kg00qf 1693 2 the the DT cord-022526-j9kg00qf 1693 3 characterization characterization NN cord-022526-j9kg00qf 1693 4 of of IN cord-022526-j9kg00qf 1693 5 seemingly seemingly RB cord-022526-j9kg00qf 1693 6 separate separate JJ cord-022526-j9kg00qf 1693 7 pathways pathway NNS cord-022526-j9kg00qf 1693 8 , , , cord-022526-j9kg00qf 1693 9 one one PRP cord-022526-j9kg00qf 1693 10 should should MD cord-022526-j9kg00qf 1693 11 recognize recognize VB cord-022526-j9kg00qf 1693 12 that that IN cord-022526-j9kg00qf 1693 13 interaction interaction NN cord-022526-j9kg00qf 1693 14 and and CC cord-022526-j9kg00qf 1693 15 synergy synergy NN cord-022526-j9kg00qf 1693 16 between between IN cord-022526-j9kg00qf 1693 17 pathways pathway NNS cord-022526-j9kg00qf 1693 18 is be VBZ cord-022526-j9kg00qf 1693 19 likely likely JJ cord-022526-j9kg00qf 1693 20 to to TO cord-022526-j9kg00qf 1693 21 occur occur VB cord-022526-j9kg00qf 1693 22 . . . cord-022526-j9kg00qf 1694 1 For for IN cord-022526-j9kg00qf 1694 2 example example NN cord-022526-j9kg00qf 1694 3 , , , cord-022526-j9kg00qf 1694 4 simultaneous simultaneous JJ cord-022526-j9kg00qf 1694 5 activation activation NN cord-022526-j9kg00qf 1694 6 of of IN cord-022526-j9kg00qf 1694 7 p38 p38 CD cord-022526-j9kg00qf 1694 8 , , , cord-022526-j9kg00qf 1694 9 c c NN cord-022526-j9kg00qf 1694 10 - - : cord-022526-j9kg00qf 1694 11 Jun Jun NNP cord-022526-j9kg00qf 1694 12 - - HYPH cord-022526-j9kg00qf 1694 13 terminal terminal JJ cord-022526-j9kg00qf 1694 14 kinase kinase NN cord-022526-j9kg00qf 1694 15 , , , cord-022526-j9kg00qf 1694 16 and and CC cord-022526-j9kg00qf 1694 17 extracellular extracellular JJ cord-022526-j9kg00qf 1694 18 signal signal NN cord-022526-j9kg00qf 1694 19 - - HYPH cord-022526-j9kg00qf 1694 20 regulated regulate VBN cord-022526-j9kg00qf 1694 21 kinase kinase NN cord-022526-j9kg00qf 1694 22 results result NNS cord-022526-j9kg00qf 1694 23 in in IN cord-022526-j9kg00qf 1694 24 much much RB cord-022526-j9kg00qf 1694 25 higher high JJR cord-022526-j9kg00qf 1694 26 levels level NNS cord-022526-j9kg00qf 1694 27 of of IN cord-022526-j9kg00qf 1694 28 tumor tumor NN cord-022526-j9kg00qf 1694 29 necrosis necrosis NN cord-022526-j9kg00qf 1694 30 factor factor NN cord-022526-j9kg00qf 1694 31 ( ( -LRB- cord-022526-j9kg00qf 1694 32 TNF TNF NNP cord-022526-j9kg00qf 1694 33 ) ) -RRB- cord-022526-j9kg00qf 1694 34 reporter reporter NN cord-022526-j9kg00qf 1694 35 expression expression NN cord-022526-j9kg00qf 1694 36 than than IN cord-022526-j9kg00qf 1694 37 activation activation NN cord-022526-j9kg00qf 1694 38 of of IN cord-022526-j9kg00qf 1694 39 a a DT cord-022526-j9kg00qf 1694 40 single single JJ cord-022526-j9kg00qf 1694 41 pathway pathway NN cord-022526-j9kg00qf 1694 42 . . . cord-022526-j9kg00qf 1695 1 44 44 CD cord-022526-j9kg00qf 1695 2 , , , cord-022526-j9kg00qf 1695 3 48 48 CD cord-022526-j9kg00qf 1695 4 Aside aside RB cord-022526-j9kg00qf 1695 5 from from IN cord-022526-j9kg00qf 1695 6 the the DT cord-022526-j9kg00qf 1695 7 mechanisms mechanism NNS cord-022526-j9kg00qf 1695 8 described describe VBN cord-022526-j9kg00qf 1695 9 here here RB cord-022526-j9kg00qf 1695 10 , , , cord-022526-j9kg00qf 1695 11 pathways pathway NNS cord-022526-j9kg00qf 1695 12 involving involve VBG cord-022526-j9kg00qf 1695 13 atypical atypical JJ cord-022526-j9kg00qf 1695 14 protein protein NN cord-022526-j9kg00qf 1695 15 kinase kinase NN cord-022526-j9kg00qf 1695 16 C C NNP cord-022526-j9kg00qf 1695 17 49,50 49,50 CD cord-022526-j9kg00qf 1695 18 and and CC cord-022526-j9kg00qf 1695 19 receptor receptor NN cord-022526-j9kg00qf 1695 20 - - HYPH cord-022526-j9kg00qf 1695 21 independent independent JJ cord-022526-j9kg00qf 1695 22 integration integration NN cord-022526-j9kg00qf 1695 23 of of IN cord-022526-j9kg00qf 1695 24 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1695 25 into into IN cord-022526-j9kg00qf 1695 26 the the DT cord-022526-j9kg00qf 1695 27 cell cell NN cord-022526-j9kg00qf 1695 28 membrane membrane NN cord-022526-j9kg00qf 1695 29 and and CC cord-022526-j9kg00qf 1695 30 ceramide ceramide NN cord-022526-j9kg00qf 1695 31 - - HYPH cord-022526-j9kg00qf 1695 32 like like JJ cord-022526-j9kg00qf 1695 33 second second JJ cord-022526-j9kg00qf 1695 34 messenger messenger NN cord-022526-j9kg00qf 1695 35 activity activity NN cord-022526-j9kg00qf 1695 36 of of IN cord-022526-j9kg00qf 1695 37 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1695 38 37 37 CD cord-022526-j9kg00qf 1695 39 have have VBP cord-022526-j9kg00qf 1695 40 been be VBN cord-022526-j9kg00qf 1695 41 proposed propose VBN cord-022526-j9kg00qf 1695 42 . . . cord-022526-j9kg00qf 1696 1 Additional additional JJ cord-022526-j9kg00qf 1696 2 pathways pathway NNS cord-022526-j9kg00qf 1696 3 are be VBP cord-022526-j9kg00qf 1696 4 likely likely JJ cord-022526-j9kg00qf 1696 5 to to TO cord-022526-j9kg00qf 1696 6 be be VB cord-022526-j9kg00qf 1696 7 uncovered uncover VBN cord-022526-j9kg00qf 1696 8 in in IN cord-022526-j9kg00qf 1696 9 the the DT cord-022526-j9kg00qf 1696 10 ongoing ongoing JJ cord-022526-j9kg00qf 1696 11 investigation investigation NN cord-022526-j9kg00qf 1696 12 of of IN cord-022526-j9kg00qf 1696 13 intracellular intracellular JJ cord-022526-j9kg00qf 1696 14 signaling signal VBG cord-022526-j9kg00qf 1696 15 mechanisms mechanism NNS cord-022526-j9kg00qf 1696 16 and and CC cord-022526-j9kg00qf 1696 17 their -PRON- PRP$ cord-022526-j9kg00qf 1696 18 in in IN cord-022526-j9kg00qf 1696 19 vivo vivo NN cord-022526-j9kg00qf 1696 20 significance significance NN cord-022526-j9kg00qf 1696 21 . . . cord-022526-j9kg00qf 1697 1 Although although IN cord-022526-j9kg00qf 1697 2 endotoxin endotoxin NN cord-022526-j9kg00qf 1697 3 can can MD cord-022526-j9kg00qf 1697 4 exert exert VB cord-022526-j9kg00qf 1697 5 some some DT cord-022526-j9kg00qf 1697 6 direct direct JJ cord-022526-j9kg00qf 1697 7 effects effect NNS cord-022526-j9kg00qf 1697 8 , , , cord-022526-j9kg00qf 1697 9 cytokines cytokine NNS cord-022526-j9kg00qf 1697 10 are be VBP cord-022526-j9kg00qf 1697 11 a a DT cord-022526-j9kg00qf 1697 12 primary primary JJ cord-022526-j9kg00qf 1697 13 mediator mediator NN cord-022526-j9kg00qf 1697 14 of of IN cord-022526-j9kg00qf 1697 15 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1697 16 effects effect NNS cord-022526-j9kg00qf 1697 17 . . . cord-022526-j9kg00qf 1698 1 Cytokines cytokine NNS cord-022526-j9kg00qf 1698 2 are be VBP cord-022526-j9kg00qf 1698 3 glycoprotein glycoprotein NN cord-022526-j9kg00qf 1698 4 molecules molecule NNS cord-022526-j9kg00qf 1698 5 that that WDT cord-022526-j9kg00qf 1698 6 regulate regulate VBP cord-022526-j9kg00qf 1698 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 1698 8 and and CC cord-022526-j9kg00qf 1698 9 immune immune JJ cord-022526-j9kg00qf 1698 10 responses response NNS cord-022526-j9kg00qf 1698 11 by by IN cord-022526-j9kg00qf 1698 12 acting act VBG cord-022526-j9kg00qf 1698 13 as as IN cord-022526-j9kg00qf 1698 14 a a DT cord-022526-j9kg00qf 1698 15 signal signal NN cord-022526-j9kg00qf 1698 16 between between IN cord-022526-j9kg00qf 1698 17 cells cell NNS cord-022526-j9kg00qf 1698 18 . . . cord-022526-j9kg00qf 1699 1 51 51 CD cord-022526-j9kg00qf 1699 2 Cytokines cytokine NNS cord-022526-j9kg00qf 1699 3 of of IN cord-022526-j9kg00qf 1699 4 major major JJ cord-022526-j9kg00qf 1699 5 interest interest NN cord-022526-j9kg00qf 1699 6 in in IN cord-022526-j9kg00qf 1699 7 the the DT cord-022526-j9kg00qf 1699 8 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1699 9 of of IN cord-022526-j9kg00qf 1699 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1699 11 include include VBP cord-022526-j9kg00qf 1699 12 TNF TNF NNP cord-022526-j9kg00qf 1699 13 , , , cord-022526-j9kg00qf 1699 14 the the DT cord-022526-j9kg00qf 1699 15 interleukins interleukin NNS cord-022526-j9kg00qf 1699 16 , , , cord-022526-j9kg00qf 1699 17 chemokines chemokine NNS cord-022526-j9kg00qf 1699 18 , , , cord-022526-j9kg00qf 1699 19 and and CC cord-022526-j9kg00qf 1699 20 growth growth NN cord-022526-j9kg00qf 1699 21 factors factor NNS cord-022526-j9kg00qf 1699 22 such such JJ cord-022526-j9kg00qf 1699 23 as as IN cord-022526-j9kg00qf 1699 24 granulocyte granulocyte NN cord-022526-j9kg00qf 1699 25 - - HYPH cord-022526-j9kg00qf 1699 26 monocyte monocyte NNP cord-022526-j9kg00qf 1699 27 colony colony NN cord-022526-j9kg00qf 1699 28 - - HYPH cord-022526-j9kg00qf 1699 29 stimulating stimulate VBG cord-022526-j9kg00qf 1699 30 factor factor NN cord-022526-j9kg00qf 1699 31 . . . cord-022526-j9kg00qf 1700 1 TNF TNF NNP cord-022526-j9kg00qf 1700 2 is be VBZ cord-022526-j9kg00qf 1700 3 thought think VBN cord-022526-j9kg00qf 1700 4 of of IN cord-022526-j9kg00qf 1700 5 as as IN cord-022526-j9kg00qf 1700 6 the the DT cord-022526-j9kg00qf 1700 7 most most RBS cord-022526-j9kg00qf 1700 8 " " `` cord-022526-j9kg00qf 1700 9 proximal proximal JJ cord-022526-j9kg00qf 1700 10 " " '' cord-022526-j9kg00qf 1700 11 cytokine cytokine NN cord-022526-j9kg00qf 1700 12 released release VBN cord-022526-j9kg00qf 1700 13 in in IN cord-022526-j9kg00qf 1700 14 response response NN cord-022526-j9kg00qf 1700 15 to to IN cord-022526-j9kg00qf 1700 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1700 17 . . . cord-022526-j9kg00qf 1701 1 Studies study NNS cord-022526-j9kg00qf 1701 2 corroborate corroborate VBP cord-022526-j9kg00qf 1701 3 this this DT cord-022526-j9kg00qf 1701 4 by by IN cord-022526-j9kg00qf 1701 5 showing show VBG cord-022526-j9kg00qf 1701 6 that that DT cord-022526-j9kg00qf 1701 7 administration administration NN cord-022526-j9kg00qf 1701 8 of of IN cord-022526-j9kg00qf 1701 9 recombinant recombinant NNP cord-022526-j9kg00qf 1701 10 TNF TNF NNP cord-022526-j9kg00qf 1701 11 mimics mimic VBZ cord-022526-j9kg00qf 1701 12 the the DT cord-022526-j9kg00qf 1701 13 effects effect NNS cord-022526-j9kg00qf 1701 14 of of IN cord-022526-j9kg00qf 1701 15 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1701 16 , , , cord-022526-j9kg00qf 1701 17 52 52 CD cord-022526-j9kg00qf 1701 18 and and CC cord-022526-j9kg00qf 1702 1 that that IN cord-022526-j9kg00qf 1702 2 antibodies antibody NNS cord-022526-j9kg00qf 1702 3 directed direct VBD cord-022526-j9kg00qf 1702 4 against against IN cord-022526-j9kg00qf 1702 5 TNF TNF NNP cord-022526-j9kg00qf 1702 6 protect protect VB cord-022526-j9kg00qf 1702 7 against against IN cord-022526-j9kg00qf 1702 8 the the DT cord-022526-j9kg00qf 1702 9 lethal lethal JJ cord-022526-j9kg00qf 1702 10 effects effect NNS cord-022526-j9kg00qf 1702 11 of of IN cord-022526-j9kg00qf 1702 12 endotoxin endotoxin NN cord-022526-j9kg00qf 1702 13 . . . cord-022526-j9kg00qf 1703 1 53 53 CD cord-022526-j9kg00qf 1703 2 Increased increase VBN cord-022526-j9kg00qf 1703 3 plasma plasma NN cord-022526-j9kg00qf 1703 4 activity activity NN cord-022526-j9kg00qf 1703 5 of of IN cord-022526-j9kg00qf 1703 6 TNF TNF NNP cord-022526-j9kg00qf 1703 7 is be VBZ cord-022526-j9kg00qf 1703 8 associated associate VBN cord-022526-j9kg00qf 1703 9 with with IN cord-022526-j9kg00qf 1703 10 increased increase VBN cord-022526-j9kg00qf 1703 11 mortality mortality NN cord-022526-j9kg00qf 1703 12 in in IN cord-022526-j9kg00qf 1703 13 equine equine JJ cord-022526-j9kg00qf 1703 14 patients patient NNS cord-022526-j9kg00qf 1703 15 with with IN cord-022526-j9kg00qf 1703 16 acute acute JJ cord-022526-j9kg00qf 1703 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1703 18 disease disease NN cord-022526-j9kg00qf 1703 19 and and CC cord-022526-j9kg00qf 1703 20 in in IN cord-022526-j9kg00qf 1703 21 septic septic JJ cord-022526-j9kg00qf 1703 22 neonates neonate NNS cord-022526-j9kg00qf 1703 23 . . . cord-022526-j9kg00qf 1704 1 14 14 CD cord-022526-j9kg00qf 1705 1 Despite despite IN cord-022526-j9kg00qf 1705 2 being be VBG cord-022526-j9kg00qf 1705 3 a a DT cord-022526-j9kg00qf 1705 4 structurally structurally RB cord-022526-j9kg00qf 1705 5 diverse diverse JJ cord-022526-j9kg00qf 1705 6 group group NN cord-022526-j9kg00qf 1705 7 of of IN cord-022526-j9kg00qf 1705 8 proteins protein NNS cord-022526-j9kg00qf 1705 9 , , , cord-022526-j9kg00qf 1705 10 cytokines cytokine NNS cord-022526-j9kg00qf 1705 11 share share VBP cord-022526-j9kg00qf 1705 12 several several JJ cord-022526-j9kg00qf 1705 13 characteristics characteristic NNS cord-022526-j9kg00qf 1705 14 that that WDT cord-022526-j9kg00qf 1705 15 allow allow VBP cord-022526-j9kg00qf 1705 16 them -PRON- PRP cord-022526-j9kg00qf 1705 17 to to TO cord-022526-j9kg00qf 1705 18 execute execute VB cord-022526-j9kg00qf 1705 19 their -PRON- PRP$ cord-022526-j9kg00qf 1705 20 complex complex JJ cord-022526-j9kg00qf 1705 21 functions function NNS cord-022526-j9kg00qf 1705 22 in in IN cord-022526-j9kg00qf 1705 23 the the DT cord-022526-j9kg00qf 1705 24 inflammatory inflammatory JJ cord-022526-j9kg00qf 1705 25 response response NN cord-022526-j9kg00qf 1705 26 . . . cord-022526-j9kg00qf 1706 1 51 51 CD cord-022526-j9kg00qf 1707 1 Any any DT cord-022526-j9kg00qf 1707 2 individual individual JJ cord-022526-j9kg00qf 1707 3 cytokine cytokine NN cord-022526-j9kg00qf 1707 4 generally generally RB cord-022526-j9kg00qf 1707 5 is be VBZ cord-022526-j9kg00qf 1707 6 produced produce VBN cord-022526-j9kg00qf 1707 7 by by IN cord-022526-j9kg00qf 1707 8 several several JJ cord-022526-j9kg00qf 1707 9 different different JJ cord-022526-j9kg00qf 1707 10 cell cell NN cord-022526-j9kg00qf 1707 11 types type NNS cord-022526-j9kg00qf 1707 12 , , , cord-022526-j9kg00qf 1707 13 can can MD cord-022526-j9kg00qf 1707 14 act act VB cord-022526-j9kg00qf 1707 15 on on IN cord-022526-j9kg00qf 1707 16 different different JJ cord-022526-j9kg00qf 1707 17 cell cell NN cord-022526-j9kg00qf 1707 18 types type NNS cord-022526-j9kg00qf 1707 19 , , , cord-022526-j9kg00qf 1707 20 and and CC cord-022526-j9kg00qf 1707 21 has have VBZ cord-022526-j9kg00qf 1707 22 multiple multiple JJ cord-022526-j9kg00qf 1707 23 effects effect NNS cord-022526-j9kg00qf 1707 24 on on IN cord-022526-j9kg00qf 1707 25 any any DT cord-022526-j9kg00qf 1707 26 given give VBN cord-022526-j9kg00qf 1707 27 cell cell NN cord-022526-j9kg00qf 1707 28 . . . cord-022526-j9kg00qf 1708 1 Furthermore furthermore RB cord-022526-j9kg00qf 1708 2 , , , cord-022526-j9kg00qf 1708 3 cytokine cytokine JJ cord-022526-j9kg00qf 1708 4 effects effect NNS cord-022526-j9kg00qf 1708 5 are be VBP cord-022526-j9kg00qf 1708 6 redundant redundant JJ cord-022526-j9kg00qf 1708 7 , , , cord-022526-j9kg00qf 1708 8 meaning mean VBG cord-022526-j9kg00qf 1708 9 that that IN cord-022526-j9kg00qf 1708 10 different different JJ cord-022526-j9kg00qf 1708 11 cytokines cytokine NNS cord-022526-j9kg00qf 1708 12 can can MD cord-022526-j9kg00qf 1708 13 share share VB cord-022526-j9kg00qf 1708 14 the the DT cord-022526-j9kg00qf 1708 15 same same JJ cord-022526-j9kg00qf 1708 16 effect effect NN cord-022526-j9kg00qf 1708 17 . . . cord-022526-j9kg00qf 1709 1 In in IN cord-022526-j9kg00qf 1709 2 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1709 3 , , , cord-022526-j9kg00qf 1709 4 this this DT cord-022526-j9kg00qf 1709 5 is be VBZ cord-022526-j9kg00qf 1709 6 particularly particularly RB cord-022526-j9kg00qf 1709 7 true true JJ cord-022526-j9kg00qf 1709 8 for for IN cord-022526-j9kg00qf 1709 9 the the DT cord-022526-j9kg00qf 1709 10 effects effect NNS cord-022526-j9kg00qf 1709 11 of of IN cord-022526-j9kg00qf 1709 12 interleukin-1 interleukin-1 NN cord-022526-j9kg00qf 1709 13 ( ( -LRB- cord-022526-j9kg00qf 1709 14 IL-1 IL-1 NNP cord-022526-j9kg00qf 1709 15 ) ) -RRB- cord-022526-j9kg00qf 1709 16 and and CC cord-022526-j9kg00qf 1709 17 TNF TNF NNP cord-022526-j9kg00qf 1709 18 . . . cord-022526-j9kg00qf 1710 1 54 54 CD cord-022526-j9kg00qf 1710 2 Many many JJ cord-022526-j9kg00qf 1710 3 of of IN cord-022526-j9kg00qf 1710 4 the the DT cord-022526-j9kg00qf 1710 5 biologic biologic JJ cord-022526-j9kg00qf 1710 6 activities activity NNS cord-022526-j9kg00qf 1710 7 of of IN cord-022526-j9kg00qf 1710 8 cytokines cytokine NNS cord-022526-j9kg00qf 1710 9 in in IN cord-022526-j9kg00qf 1710 10 vivo vivo NN cord-022526-j9kg00qf 1710 11 result result NN cord-022526-j9kg00qf 1710 12 from from IN cord-022526-j9kg00qf 1710 13 synergistic synergistic JJ cord-022526-j9kg00qf 1710 14 or or CC cord-022526-j9kg00qf 1710 15 antagonistic antagonistic JJ cord-022526-j9kg00qf 1710 16 actions action NNS cord-022526-j9kg00qf 1710 17 involving involve VBG cord-022526-j9kg00qf 1710 18 two two CD cord-022526-j9kg00qf 1710 19 or or CC cord-022526-j9kg00qf 1710 20 more more JJR cord-022526-j9kg00qf 1710 21 cytokines cytokine NNS cord-022526-j9kg00qf 1710 22 . . . cord-022526-j9kg00qf 1711 1 55 55 CD cord-022526-j9kg00qf 1712 1 Within within IN cord-022526-j9kg00qf 1712 2 itself -PRON- PRP cord-022526-j9kg00qf 1712 3 the the DT cord-022526-j9kg00qf 1712 4 cytokine cytokine NN cord-022526-j9kg00qf 1712 5 response response NN cord-022526-j9kg00qf 1712 6 is be VBZ cord-022526-j9kg00qf 1712 7 highly highly RB cord-022526-j9kg00qf 1712 8 regulated regulate VBN cord-022526-j9kg00qf 1712 9 : : : cord-022526-j9kg00qf 1712 10 cytokines cytokine NNS cord-022526-j9kg00qf 1712 11 induce induce VBP cord-022526-j9kg00qf 1712 12 or or CC cord-022526-j9kg00qf 1712 13 suppress suppress VBP cord-022526-j9kg00qf 1712 14 synthesis synthesis NN cord-022526-j9kg00qf 1712 15 of of IN cord-022526-j9kg00qf 1712 16 other other JJ cord-022526-j9kg00qf 1712 17 cytokines cytokine NNS cord-022526-j9kg00qf 1712 18 including include VBG cord-022526-j9kg00qf 1712 19 their -PRON- PRP$ cord-022526-j9kg00qf 1712 20 own own JJ cord-022526-j9kg00qf 1712 21 ( ( -LRB- cord-022526-j9kg00qf 1712 22 feedback feedback NN cord-022526-j9kg00qf 1712 23 regulation regulation NN cord-022526-j9kg00qf 1712 24 ) ) -RRB- cord-022526-j9kg00qf 1712 25 , , , cord-022526-j9kg00qf 1712 26 regulate regulate VB cord-022526-j9kg00qf 1712 27 expression expression NN cord-022526-j9kg00qf 1712 28 of of IN cord-022526-j9kg00qf 1712 29 cytokine cytokine JJ cord-022526-j9kg00qf 1712 30 receptors receptor NNS cord-022526-j9kg00qf 1712 31 , , , cord-022526-j9kg00qf 1712 32 and and CC cord-022526-j9kg00qf 1712 33 regulate regulate VB cord-022526-j9kg00qf 1712 34 cytokine cytokine NN cord-022526-j9kg00qf 1712 35 activities activity NNS cord-022526-j9kg00qf 1712 36 . . . cord-022526-j9kg00qf 1713 1 Additional additional JJ cord-022526-j9kg00qf 1713 2 regulatory regulatory JJ cord-022526-j9kg00qf 1713 3 mechanisms mechanism NNS cord-022526-j9kg00qf 1713 4 include include VBP cord-022526-j9kg00qf 1713 5 the the DT cord-022526-j9kg00qf 1713 6 release release NN cord-022526-j9kg00qf 1713 7 of of IN cord-022526-j9kg00qf 1713 8 specific specific JJ cord-022526-j9kg00qf 1713 9 cytokine cytokine NN cord-022526-j9kg00qf 1713 10 inhibitors inhibitor NNS cord-022526-j9kg00qf 1713 11 such such JJ cord-022526-j9kg00qf 1713 12 as as IN cord-022526-j9kg00qf 1713 13 soluble soluble JJ cord-022526-j9kg00qf 1713 14 IL-1 IL-1 NNP cord-022526-j9kg00qf 1713 15 and and CC cord-022526-j9kg00qf 1713 16 TNF TNF NNP cord-022526-j9kg00qf 1713 17 - - HYPH cord-022526-j9kg00qf 1713 18 α α NNP cord-022526-j9kg00qf 1713 19 receptors receptor NNS cord-022526-j9kg00qf 1713 20 , , , cord-022526-j9kg00qf 1713 21 cytokine cytokine JJ cord-022526-j9kg00qf 1713 22 receptor receptor NN cord-022526-j9kg00qf 1713 23 antagonists antagonist NNS cord-022526-j9kg00qf 1713 24 such such JJ cord-022526-j9kg00qf 1713 25 as as IN cord-022526-j9kg00qf 1713 26 IL-1 IL-1 NNP cord-022526-j9kg00qf 1713 27 receptor receptor NN cord-022526-j9kg00qf 1713 28 antagonist antagonist NN cord-022526-j9kg00qf 1713 29 , , , cord-022526-j9kg00qf 1713 30 and and CC cord-022526-j9kg00qf 1713 31 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1713 32 cytokines cytokine NNS cord-022526-j9kg00qf 1713 33 including include VBG cord-022526-j9kg00qf 1713 34 IL-10 IL-10 NNP cord-022526-j9kg00qf 1713 35 , , , cord-022526-j9kg00qf 1713 36 IL-4 IL-4 NNP cord-022526-j9kg00qf 1713 37 , , , cord-022526-j9kg00qf 1713 38 IL-13 IL-13 NNP cord-022526-j9kg00qf 1713 39 , , , cord-022526-j9kg00qf 1713 40 and and CC cord-022526-j9kg00qf 1713 41 transforming transform VBG cord-022526-j9kg00qf 1713 42 growth growth NN cord-022526-j9kg00qf 1713 43 factor factor NN cord-022526-j9kg00qf 1713 44 β β NN cord-022526-j9kg00qf 1713 45 . . . cord-022526-j9kg00qf 1714 1 Glucocorticoids Glucocorticoids NNP cord-022526-j9kg00qf 1714 2 also also RB cord-022526-j9kg00qf 1714 3 are be VBP cord-022526-j9kg00qf 1714 4 produced produce VBN cord-022526-j9kg00qf 1714 5 increasingly increasingly RB cord-022526-j9kg00qf 1714 6 in in IN cord-022526-j9kg00qf 1714 7 response response NN cord-022526-j9kg00qf 1714 8 to to IN cord-022526-j9kg00qf 1714 9 endotoxin endotoxin NN cord-022526-j9kg00qf 1714 10 and and CC cord-022526-j9kg00qf 1714 11 inhibit inhibit VB cord-022526-j9kg00qf 1714 12 the the DT cord-022526-j9kg00qf 1714 13 production production NN cord-022526-j9kg00qf 1714 14 of of IN cord-022526-j9kg00qf 1714 15 cytokines cytokine NNS cord-022526-j9kg00qf 1714 16 . . . cord-022526-j9kg00qf 1715 1 56 56 CD cord-022526-j9kg00qf 1716 1 During during IN cord-022526-j9kg00qf 1716 2 a a DT cord-022526-j9kg00qf 1716 3 controlled control VBN cord-022526-j9kg00qf 1716 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 1716 5 response response NN cord-022526-j9kg00qf 1716 6 , , , cord-022526-j9kg00qf 1716 7 therefore therefore RB cord-022526-j9kg00qf 1716 8 , , , cord-022526-j9kg00qf 1716 9 cytokine cytokine JJ cord-022526-j9kg00qf 1716 10 secretion secretion NN cord-022526-j9kg00qf 1716 11 is be VBZ cord-022526-j9kg00qf 1716 12 a a DT cord-022526-j9kg00qf 1716 13 selflimited selflimited JJ cord-022526-j9kg00qf 1716 14 event event NN cord-022526-j9kg00qf 1716 15 , , , cord-022526-j9kg00qf 1716 16 whereas whereas IN cord-022526-j9kg00qf 1716 17 excessive excessive JJ cord-022526-j9kg00qf 1716 18 stimulation stimulation NN cord-022526-j9kg00qf 1716 19 of of IN cord-022526-j9kg00qf 1716 20 cytokine cytokine NN cord-022526-j9kg00qf 1716 21 release release NN cord-022526-j9kg00qf 1716 22 can can MD cord-022526-j9kg00qf 1716 23 lead lead VB cord-022526-j9kg00qf 1716 24 to to IN cord-022526-j9kg00qf 1716 25 the the DT cord-022526-j9kg00qf 1716 26 perpetuation perpetuation NN cord-022526-j9kg00qf 1716 27 of of IN cord-022526-j9kg00qf 1716 28 the the DT cord-022526-j9kg00qf 1716 29 inflammatory inflammatory JJ cord-022526-j9kg00qf 1716 30 response response NN cord-022526-j9kg00qf 1716 31 even even RB cord-022526-j9kg00qf 1716 32 after after IN cord-022526-j9kg00qf 1716 33 the the DT cord-022526-j9kg00qf 1716 34 initial initial JJ cord-022526-j9kg00qf 1716 35 stimulus stimulus NN cord-022526-j9kg00qf 1716 36 has have VBZ cord-022526-j9kg00qf 1716 37 been be VBN cord-022526-j9kg00qf 1716 38 removed remove VBN cord-022526-j9kg00qf 1716 39 . . . cord-022526-j9kg00qf 1717 1 Conversely conversely RB cord-022526-j9kg00qf 1717 2 , , , cord-022526-j9kg00qf 1717 3 the the DT cord-022526-j9kg00qf 1717 4 compensatory compensatory JJ cord-022526-j9kg00qf 1717 5 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1717 6 reaction reaction NN cord-022526-j9kg00qf 1717 7 can can MD cord-022526-j9kg00qf 1717 8 become become VB cord-022526-j9kg00qf 1717 9 severe severe JJ cord-022526-j9kg00qf 1717 10 enough enough RB cord-022526-j9kg00qf 1717 11 to to TO cord-022526-j9kg00qf 1717 12 cause cause VB cord-022526-j9kg00qf 1717 13 anergy anergy NNP cord-022526-j9kg00qf 1717 14 of of IN cord-022526-j9kg00qf 1717 15 the the DT cord-022526-j9kg00qf 1717 16 immune immune JJ cord-022526-j9kg00qf 1717 17 system system NN cord-022526-j9kg00qf 1717 18 and and CC cord-022526-j9kg00qf 1717 19 increased increase VBN cord-022526-j9kg00qf 1717 20 susceptibility susceptibility NN cord-022526-j9kg00qf 1717 21 to to IN cord-022526-j9kg00qf 1717 22 infection infection NN cord-022526-j9kg00qf 1717 23 , , , cord-022526-j9kg00qf 1717 24 which which WDT cord-022526-j9kg00qf 1717 25 has have VBZ cord-022526-j9kg00qf 1717 26 been be VBN cord-022526-j9kg00qf 1717 27 termed term VBN cord-022526-j9kg00qf 1717 28 the the DT cord-022526-j9kg00qf 1717 29 compensatory compensatory JJ cord-022526-j9kg00qf 1717 30 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1717 31 response response NN cord-022526-j9kg00qf 1717 32 syndrome syndrome NN cord-022526-j9kg00qf 1717 33 . . . cord-022526-j9kg00qf 1718 1 Overall overall RB cord-022526-j9kg00qf 1718 2 , , , cord-022526-j9kg00qf 1718 3 excessive excessive JJ cord-022526-j9kg00qf 1718 4 and and CC cord-022526-j9kg00qf 1718 5 unbalanced unbalanced JJ cord-022526-j9kg00qf 1718 6 stimulation stimulation NN cord-022526-j9kg00qf 1718 7 of of IN cord-022526-j9kg00qf 1718 8 the the DT cord-022526-j9kg00qf 1718 9 immune immune JJ cord-022526-j9kg00qf 1718 10 system system NN cord-022526-j9kg00qf 1718 11 therefore therefore RB cord-022526-j9kg00qf 1718 12 may may MD cord-022526-j9kg00qf 1718 13 result result VB cord-022526-j9kg00qf 1718 14 in in IN cord-022526-j9kg00qf 1718 15 predominantly predominantly RB cord-022526-j9kg00qf 1718 16 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 1718 17 ( ( -LRB- cord-022526-j9kg00qf 1718 18 systemic systemic JJ cord-022526-j9kg00qf 1718 19 inflammatory inflammatory JJ cord-022526-j9kg00qf 1718 20 response response NN cord-022526-j9kg00qf 1718 21 syndrome syndrome NN cord-022526-j9kg00qf 1718 22 ) ) -RRB- cord-022526-j9kg00qf 1718 23 , , , cord-022526-j9kg00qf 1718 24 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1718 25 ( ( -LRB- cord-022526-j9kg00qf 1718 26 compensatory compensatory JJ cord-022526-j9kg00qf 1718 27 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 1718 28 response response NN cord-022526-j9kg00qf 1718 29 syndrome syndrome NN cord-022526-j9kg00qf 1718 30 ) ) -RRB- cord-022526-j9kg00qf 1718 31 , , , cord-022526-j9kg00qf 1718 32 or or CC cord-022526-j9kg00qf 1718 33 combined combine VBN cord-022526-j9kg00qf 1718 34 ( ( -LRB- cord-022526-j9kg00qf 1718 35 mixed mixed JJ cord-022526-j9kg00qf 1718 36 antagonist antagonist NN cord-022526-j9kg00qf 1718 37 response response NN cord-022526-j9kg00qf 1718 38 syndrome syndrome NN cord-022526-j9kg00qf 1718 39 ) ) -RRB- cord-022526-j9kg00qf 1718 40 responses response NNS cord-022526-j9kg00qf 1718 41 . . . cord-022526-j9kg00qf 1719 1 57 57 CD cord-022526-j9kg00qf 1720 1 Interestingly interestingly RB cord-022526-j9kg00qf 1720 2 , , , cord-022526-j9kg00qf 1720 3 tolerance tolerance NN cord-022526-j9kg00qf 1720 4 to to IN cord-022526-j9kg00qf 1720 5 endotoxin endotoxin NN cord-022526-j9kg00qf 1720 6 develops develop NNS cord-022526-j9kg00qf 1720 7 after after IN cord-022526-j9kg00qf 1720 8 repeated repeat VBN cord-022526-j9kg00qf 1720 9 exposure exposure NN cord-022526-j9kg00qf 1720 10 to to IN cord-022526-j9kg00qf 1720 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1720 12 . . . cord-022526-j9kg00qf 1721 1 58 58 CD cord-022526-j9kg00qf 1721 2 Tolerance tolerance NN cord-022526-j9kg00qf 1721 3 can can MD cord-022526-j9kg00qf 1721 4 be be VB cord-022526-j9kg00qf 1721 5 demonstrated demonstrate VBN cord-022526-j9kg00qf 1721 6 in in IN cord-022526-j9kg00qf 1721 7 vitro vitro FW cord-022526-j9kg00qf 1721 8 and and CC cord-022526-j9kg00qf 1721 9 in in IN cord-022526-j9kg00qf 1721 10 vivo vivo NN cord-022526-j9kg00qf 1721 11 and and CC cord-022526-j9kg00qf 1721 12 encompasses encompass VBZ cord-022526-j9kg00qf 1721 13 decreased decreased JJ cord-022526-j9kg00qf 1721 14 production production NN cord-022526-j9kg00qf 1721 15 of of IN cord-022526-j9kg00qf 1721 16 cytokines cytokine NNS cord-022526-j9kg00qf 1721 17 and and CC cord-022526-j9kg00qf 1721 18 a a DT cord-022526-j9kg00qf 1721 19 diminished diminished JJ cord-022526-j9kg00qf 1721 20 clinical clinical JJ cord-022526-j9kg00qf 1721 21 response response NN cord-022526-j9kg00qf 1721 22 . . . cord-022526-j9kg00qf 1722 1 58 58 CD cord-022526-j9kg00qf 1722 2 , , , cord-022526-j9kg00qf 1722 3 59 59 CD cord-022526-j9kg00qf 1722 4 Mechanisms mechanism NNS cord-022526-j9kg00qf 1722 5 that that WDT cord-022526-j9kg00qf 1722 6 likely likely RB cord-022526-j9kg00qf 1722 7 are be VBP cord-022526-j9kg00qf 1722 8 responsible responsible JJ cord-022526-j9kg00qf 1722 9 for for IN cord-022526-j9kg00qf 1722 10 the the DT cord-022526-j9kg00qf 1722 11 development development NN cord-022526-j9kg00qf 1722 12 of of IN cord-022526-j9kg00qf 1722 13 endotoxin endotoxin NN cord-022526-j9kg00qf 1722 14 tolerance tolerance NN cord-022526-j9kg00qf 1722 15 include include VBP cord-022526-j9kg00qf 1722 16 receptor receptor NN cord-022526-j9kg00qf 1722 17 downregulation downregulation NN cord-022526-j9kg00qf 1722 18 and and CC cord-022526-j9kg00qf 1722 19 inhibition inhibition NN cord-022526-j9kg00qf 1722 20 of of IN cord-022526-j9kg00qf 1722 21 intracellular intracellular JJ cord-022526-j9kg00qf 1722 22 signaling signal VBG cord-022526-j9kg00qf 1722 23 pathways pathway NNS cord-022526-j9kg00qf 1722 24 . . . cord-022526-j9kg00qf 1723 1 60 60 CD cord-022526-j9kg00qf 1723 2 , , , cord-022526-j9kg00qf 1723 3 61 61 CD cord-022526-j9kg00qf 1723 4 Cytokines cytokine NNS cord-022526-j9kg00qf 1723 5 such such JJ cord-022526-j9kg00qf 1723 6 as as IN cord-022526-j9kg00qf 1723 7 TNF TNF NNP cord-022526-j9kg00qf 1723 8 are be VBP cord-022526-j9kg00qf 1723 9 important important JJ cord-022526-j9kg00qf 1723 10 mediators mediator NNS cord-022526-j9kg00qf 1723 11 in in IN cord-022526-j9kg00qf 1723 12 the the DT cord-022526-j9kg00qf 1723 13 development development NN cord-022526-j9kg00qf 1723 14 of of IN cord-022526-j9kg00qf 1723 15 endotoxin endotoxin NN cord-022526-j9kg00qf 1723 16 tolerance tolerance NN cord-022526-j9kg00qf 1723 17 . . . cord-022526-j9kg00qf 1724 1 62 62 CD cord-022526-j9kg00qf 1725 1 The the DT cord-022526-j9kg00qf 1725 2 development development NN cord-022526-j9kg00qf 1725 3 of of IN cord-022526-j9kg00qf 1725 4 endotoxin endotoxin NN cord-022526-j9kg00qf 1725 5 tolerance tolerance NN cord-022526-j9kg00qf 1725 6 in in IN cord-022526-j9kg00qf 1725 7 horses horse NNS cord-022526-j9kg00qf 1725 8 has have VBZ cord-022526-j9kg00qf 1725 9 been be VBN cord-022526-j9kg00qf 1725 10 reported report VBN cord-022526-j9kg00qf 1725 11 . . . cord-022526-j9kg00qf 1726 1 63 63 CD cord-022526-j9kg00qf 1726 2 , , , cord-022526-j9kg00qf 1726 3 64 64 CD cord-022526-j9kg00qf 1726 4 Aside aside RB cord-022526-j9kg00qf 1726 5 from from IN cord-022526-j9kg00qf 1726 6 cytokines cytokine NNS cord-022526-j9kg00qf 1726 7 , , , cord-022526-j9kg00qf 1726 8 a a DT cord-022526-j9kg00qf 1726 9 number number NN cord-022526-j9kg00qf 1726 10 of of IN cord-022526-j9kg00qf 1726 11 other other JJ cord-022526-j9kg00qf 1726 12 molecules molecule NNS cord-022526-j9kg00qf 1726 13 function function VBP cord-022526-j9kg00qf 1726 14 as as IN cord-022526-j9kg00qf 1726 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 1726 16 mediators mediator NNS cord-022526-j9kg00qf 1726 17 in in IN cord-022526-j9kg00qf 1726 18 the the DT cord-022526-j9kg00qf 1726 19 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1726 20 of of IN cord-022526-j9kg00qf 1726 21 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1726 22 , , , cord-022526-j9kg00qf 1726 23 the the DT cord-022526-j9kg00qf 1726 24 synthesis synthesis NN cord-022526-j9kg00qf 1726 25 and and CC cord-022526-j9kg00qf 1726 26 release release NN cord-022526-j9kg00qf 1726 27 of of IN cord-022526-j9kg00qf 1726 28 which which WDT cord-022526-j9kg00qf 1726 29 are be VBP cord-022526-j9kg00qf 1726 30 stimulated stimulate VBN cord-022526-j9kg00qf 1726 31 by by IN cord-022526-j9kg00qf 1726 32 endotoxin endotoxin NN cord-022526-j9kg00qf 1726 33 and and CC cord-022526-j9kg00qf 1726 34 by by IN cord-022526-j9kg00qf 1726 35 cytokines cytokine NNS cord-022526-j9kg00qf 1726 36 . . . cord-022526-j9kg00qf 1727 1 These these DT cord-022526-j9kg00qf 1727 2 mediators mediator NNS cord-022526-j9kg00qf 1727 3 include include VBP cord-022526-j9kg00qf 1727 4 the the DT cord-022526-j9kg00qf 1727 5 arachidonic arachidonic JJ cord-022526-j9kg00qf 1727 6 acid acid NN cord-022526-j9kg00qf 1727 7 metabolites metabolite NNS cord-022526-j9kg00qf 1727 8 or or CC cord-022526-j9kg00qf 1727 9 prostanoids prostanoid NNS cord-022526-j9kg00qf 1727 10 , , , cord-022526-j9kg00qf 1727 11 platelet platelet NN cord-022526-j9kg00qf 1727 12 - - HYPH cord-022526-j9kg00qf 1727 13 activating activate VBG cord-022526-j9kg00qf 1727 14 factor factor NN cord-022526-j9kg00qf 1727 15 ( ( -LRB- cord-022526-j9kg00qf 1727 16 PAF PAF NNP cord-022526-j9kg00qf 1727 17 ) ) -RRB- cord-022526-j9kg00qf 1727 18 , , , cord-022526-j9kg00qf 1727 19 oxygenderived oxygenderive VBD cord-022526-j9kg00qf 1727 20 free free JJ cord-022526-j9kg00qf 1727 21 radicals radical NNS cord-022526-j9kg00qf 1727 22 , , , cord-022526-j9kg00qf 1727 23 nitric nitric NN cord-022526-j9kg00qf 1727 24 oxide oxide NN cord-022526-j9kg00qf 1727 25 ( ( -LRB- cord-022526-j9kg00qf 1727 26 NO no UH cord-022526-j9kg00qf 1727 27 ) ) -RRB- cord-022526-j9kg00qf 1727 28 , , , cord-022526-j9kg00qf 1727 29 histamine histamine NN cord-022526-j9kg00qf 1727 30 , , , cord-022526-j9kg00qf 1727 31 kinins kinin NNS cord-022526-j9kg00qf 1727 32 , , , cord-022526-j9kg00qf 1727 33 and and CC cord-022526-j9kg00qf 1727 34 complement complement VB cord-022526-j9kg00qf 1727 35 components component NNS cord-022526-j9kg00qf 1727 36 . . . cord-022526-j9kg00qf 1728 1 Table table NN cord-022526-j9kg00qf 1728 2 13 13 CD cord-022526-j9kg00qf 1728 3 .7 .7 CD cord-022526-j9kg00qf 1728 4 - - HYPH cord-022526-j9kg00qf 1728 5 1 1 CD cord-022526-j9kg00qf 1728 6 summarizes summarize VBZ cord-022526-j9kg00qf 1728 7 the the DT cord-022526-j9kg00qf 1728 8 origins origin NNS cord-022526-j9kg00qf 1728 9 , , , cord-022526-j9kg00qf 1728 10 targets target NNS cord-022526-j9kg00qf 1728 11 , , , cord-022526-j9kg00qf 1728 12 and and CC cord-022526-j9kg00qf 1728 13 effects effect NNS cord-022526-j9kg00qf 1728 14 of of IN cord-022526-j9kg00qf 1728 15 the the DT cord-022526-j9kg00qf 1728 16 most most RBS cord-022526-j9kg00qf 1728 17 important important JJ cord-022526-j9kg00qf 1728 18 inflammatory inflammatory JJ cord-022526-j9kg00qf 1728 19 mediators mediator NNS cord-022526-j9kg00qf 1728 20 involved involve VBN cord-022526-j9kg00qf 1728 21 in in IN cord-022526-j9kg00qf 1728 22 the the DT cord-022526-j9kg00qf 1728 23 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1728 24 of of IN cord-022526-j9kg00qf 1728 25 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1728 26 . . . cord-022526-j9kg00qf 1729 1 Figure figure NN cord-022526-j9kg00qf 1729 2 13 13 CD cord-022526-j9kg00qf 1729 3 .7 .7 CD cord-022526-j9kg00qf 1729 4 - - HYPH cord-022526-j9kg00qf 1729 5 5 5 CD cord-022526-j9kg00qf 1729 6 shows show VBZ cord-022526-j9kg00qf 1729 7 the the DT cord-022526-j9kg00qf 1729 8 pathways pathway NNS cord-022526-j9kg00qf 1729 9 of of IN cord-022526-j9kg00qf 1729 10 arachidonic arachidonic JJ cord-022526-j9kg00qf 1729 11 acid acid NN cord-022526-j9kg00qf 1729 12 metabolism metabolism NN cord-022526-j9kg00qf 1729 13 by by IN cord-022526-j9kg00qf 1729 14 COX COX NNP cord-022526-j9kg00qf 1729 15 and and CC cord-022526-j9kg00qf 1729 16 lipoxygenase lipoxygenase NNP cord-022526-j9kg00qf 1729 17 . . . cord-022526-j9kg00qf 1730 1 COX COX NNP cord-022526-j9kg00qf 1730 2 products product NNS cord-022526-j9kg00qf 1730 3 are be VBP cord-022526-j9kg00qf 1730 4 the the DT cord-022526-j9kg00qf 1730 5 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 1730 6 ( ( -LRB- cord-022526-j9kg00qf 1730 7 PGs pg NNS cord-022526-j9kg00qf 1730 8 ) ) -RRB- cord-022526-j9kg00qf 1730 9 , , , cord-022526-j9kg00qf 1730 10 prostacyclin prostacyclin NNP cord-022526-j9kg00qf 1730 11 ( ( -LRB- cord-022526-j9kg00qf 1730 12 PGI PGI NNP cord-022526-j9kg00qf 1730 13 2 2 CD cord-022526-j9kg00qf 1730 14 ) ) -RRB- cord-022526-j9kg00qf 1730 15 and and CC cord-022526-j9kg00qf 1730 16 thromboxanes thromboxane NNS cord-022526-j9kg00qf 1730 17 , , , cord-022526-j9kg00qf 1730 18 and and CC cord-022526-j9kg00qf 1730 19 the the DT cord-022526-j9kg00qf 1730 20 lipoxygenase lipoxygenase NN cord-022526-j9kg00qf 1730 21 produces produce VBZ cord-022526-j9kg00qf 1730 22 the the DT cord-022526-j9kg00qf 1730 23 leukotrienes leukotriene NNS cord-022526-j9kg00qf 1730 24 . . . cord-022526-j9kg00qf 1730 25 _SP cord-022526-j9kg00qf 1731 1 The the DT cord-022526-j9kg00qf 1731 2 innate innate JJ cord-022526-j9kg00qf 1731 3 immune immune JJ cord-022526-j9kg00qf 1731 4 response response NN cord-022526-j9kg00qf 1731 5 to to IN cord-022526-j9kg00qf 1731 6 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1731 7 is be VBZ cord-022526-j9kg00qf 1731 8 an an DT cord-022526-j9kg00qf 1731 9 efficient efficient JJ cord-022526-j9kg00qf 1731 10 defense defense NN cord-022526-j9kg00qf 1731 11 mechanism mechanism NN cord-022526-j9kg00qf 1731 12 that that WDT cord-022526-j9kg00qf 1731 13 provides provide VBZ cord-022526-j9kg00qf 1731 14 maintenance maintenance NN cord-022526-j9kg00qf 1731 15 of of IN cord-022526-j9kg00qf 1731 16 homeostasis homeostasis NN cord-022526-j9kg00qf 1731 17 and and CC cord-022526-j9kg00qf 1731 18 therefore therefore RB cord-022526-j9kg00qf 1731 19 health health NN cord-022526-j9kg00qf 1731 20 in in IN cord-022526-j9kg00qf 1731 21 the the DT cord-022526-j9kg00qf 1731 22 face face NN cord-022526-j9kg00qf 1731 23 of of IN cord-022526-j9kg00qf 1731 24 an an DT cord-022526-j9kg00qf 1731 25 almost almost RB cord-022526-j9kg00qf 1731 26 continuous continuous JJ cord-022526-j9kg00qf 1731 27 exposure exposure NN cord-022526-j9kg00qf 1731 28 to to IN cord-022526-j9kg00qf 1731 29 microorganisms microorganism NNS cord-022526-j9kg00qf 1731 30 and and CC cord-022526-j9kg00qf 1731 31 their -PRON- PRP$ cord-022526-j9kg00qf 1731 32 products product NNS cord-022526-j9kg00qf 1731 33 . . . cord-022526-j9kg00qf 1732 1 65 65 CD cord-022526-j9kg00qf 1732 2 Detrimental detrimental JJ cord-022526-j9kg00qf 1732 3 consequences consequence NNS cord-022526-j9kg00qf 1732 4 of of IN cord-022526-j9kg00qf 1732 5 this this DT cord-022526-j9kg00qf 1732 6 immune immune JJ cord-022526-j9kg00qf 1732 7 response response NN cord-022526-j9kg00qf 1732 8 only only RB cord-022526-j9kg00qf 1732 9 occur occur VBP cord-022526-j9kg00qf 1732 10 if if IN cord-022526-j9kg00qf 1732 11 excessive excessive JJ cord-022526-j9kg00qf 1732 12 and and CC cord-022526-j9kg00qf 1732 13 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 1732 14 mediator mediator NN cord-022526-j9kg00qf 1732 15 output output NN cord-022526-j9kg00qf 1732 16 results result NNS cord-022526-j9kg00qf 1732 17 in in IN cord-022526-j9kg00qf 1732 18 endothelial endothelial JJ cord-022526-j9kg00qf 1732 19 damage damage NN cord-022526-j9kg00qf 1732 20 , , , cord-022526-j9kg00qf 1732 21 neutrophil neutrophil NN cord-022526-j9kg00qf 1732 22 - - HYPH cord-022526-j9kg00qf 1732 23 mediated mediate VBN cord-022526-j9kg00qf 1732 24 tissue tissue NN cord-022526-j9kg00qf 1732 25 damage damage NN cord-022526-j9kg00qf 1732 26 , , , cord-022526-j9kg00qf 1732 27 and and CC cord-022526-j9kg00qf 1732 28 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 1732 29 activation activation NN cord-022526-j9kg00qf 1732 30 of of IN cord-022526-j9kg00qf 1732 31 the the DT cord-022526-j9kg00qf 1732 32 coagulation coagulation NN cord-022526-j9kg00qf 1732 33 and and CC cord-022526-j9kg00qf 1732 34 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 1732 35 cascades cascade NNS cord-022526-j9kg00qf 1732 36 and and CC cord-022526-j9kg00qf 1732 37 the the DT cord-022526-j9kg00qf 1732 38 complement complement NN cord-022526-j9kg00qf 1732 39 system system NN cord-022526-j9kg00qf 1732 40 . . . cord-022526-j9kg00qf 1733 1 Ultimately ultimately RB cord-022526-j9kg00qf 1733 2 , , , cord-022526-j9kg00qf 1733 3 the the DT cord-022526-j9kg00qf 1733 4 combination combination NN cord-022526-j9kg00qf 1733 5 of of IN cord-022526-j9kg00qf 1733 6 these these DT cord-022526-j9kg00qf 1733 7 events event NNS cord-022526-j9kg00qf 1733 8 culminates culminate VBZ cord-022526-j9kg00qf 1733 9 in in IN cord-022526-j9kg00qf 1733 10 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 1733 11 instability instability NN cord-022526-j9kg00qf 1733 12 , , , cord-022526-j9kg00qf 1733 13 impaired impair VBN cord-022526-j9kg00qf 1733 14 hemostasis hemostasis NN cord-022526-j9kg00qf 1733 15 , , , cord-022526-j9kg00qf 1733 16 organ organ NN cord-022526-j9kg00qf 1733 17 failure failure NN cord-022526-j9kg00qf 1733 18 , , , cord-022526-j9kg00qf 1733 19 shock shock NN cord-022526-j9kg00qf 1733 20 , , , cord-022526-j9kg00qf 1733 21 and and CC cord-022526-j9kg00qf 1733 22 death death NN cord-022526-j9kg00qf 1733 23 . . . cord-022526-j9kg00qf 1734 1 The the DT cord-022526-j9kg00qf 1734 2 following follow VBG cord-022526-j9kg00qf 1734 3 discussion discussion NN cord-022526-j9kg00qf 1734 4 addresses address VBZ cord-022526-j9kg00qf 1734 5 the the DT cord-022526-j9kg00qf 1734 6 various various JJ cord-022526-j9kg00qf 1734 7 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 1734 8 events event NNS cord-022526-j9kg00qf 1734 9 in in IN cord-022526-j9kg00qf 1734 10 the the DT cord-022526-j9kg00qf 1734 11 development development NN cord-022526-j9kg00qf 1734 12 of of IN cord-022526-j9kg00qf 1734 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1734 14 and and CC cord-022526-j9kg00qf 1734 15 shock shock NN cord-022526-j9kg00qf 1734 16 and and CC cord-022526-j9kg00qf 1734 17 the the DT cord-022526-j9kg00qf 1734 18 role role NN cord-022526-j9kg00qf 1734 19 of of IN cord-022526-j9kg00qf 1734 20 inflammatory inflammatory JJ cord-022526-j9kg00qf 1734 21 mediators mediator NNS cord-022526-j9kg00qf 1734 22 . . . cord-022526-j9kg00qf 1735 1 Normal normal JJ cord-022526-j9kg00qf 1735 2 endothelium endothelium NN cord-022526-j9kg00qf 1735 3 plays play VBZ cord-022526-j9kg00qf 1735 4 an an DT cord-022526-j9kg00qf 1735 5 important important JJ cord-022526-j9kg00qf 1735 6 role role NN cord-022526-j9kg00qf 1735 7 in in IN cord-022526-j9kg00qf 1735 8 regulating regulate VBG cord-022526-j9kg00qf 1735 9 blood blood NN cord-022526-j9kg00qf 1735 10 pressure pressure NN cord-022526-j9kg00qf 1735 11 and and CC cord-022526-j9kg00qf 1735 12 regional regional JJ cord-022526-j9kg00qf 1735 13 tissue tissue NN cord-022526-j9kg00qf 1735 14 perfusion perfusion NN cord-022526-j9kg00qf 1735 15 and and CC cord-022526-j9kg00qf 1735 16 provides provide VBZ cord-022526-j9kg00qf 1735 17 an an DT cord-022526-j9kg00qf 1735 18 anticoagulant anticoagulant JJ cord-022526-j9kg00qf 1735 19 surface surface NN cord-022526-j9kg00qf 1735 20 . . . cord-022526-j9kg00qf 1736 1 Endothelial endothelial JJ cord-022526-j9kg00qf 1736 2 dysfunction dysfunction NN cord-022526-j9kg00qf 1736 3 and and CC cord-022526-j9kg00qf 1736 4 damage damage NN cord-022526-j9kg00qf 1736 5 result result NN cord-022526-j9kg00qf 1736 6 in in IN cord-022526-j9kg00qf 1736 7 a a DT cord-022526-j9kg00qf 1736 8 decreased decreased JJ cord-022526-j9kg00qf 1736 9 responsiveness responsiveness NN cord-022526-j9kg00qf 1736 10 to to IN cord-022526-j9kg00qf 1736 11 vasoactive vasoactive JJ cord-022526-j9kg00qf 1736 12 agents agent NNS cord-022526-j9kg00qf 1736 13 ( ( -LRB- cord-022526-j9kg00qf 1736 14 vasoplegia vasoplegia NNP cord-022526-j9kg00qf 1736 15 ) ) -RRB- cord-022526-j9kg00qf 1736 16 , , , cord-022526-j9kg00qf 1736 17 increased increase VBN cord-022526-j9kg00qf 1736 18 vascular vascular JJ cord-022526-j9kg00qf 1736 19 permeability permeability NN cord-022526-j9kg00qf 1736 20 , , , cord-022526-j9kg00qf 1736 21 and and CC cord-022526-j9kg00qf 1736 22 a a DT cord-022526-j9kg00qf 1736 23 tendency tendency NN cord-022526-j9kg00qf 1736 24 for for IN cord-022526-j9kg00qf 1736 25 clot clot NN cord-022526-j9kg00qf 1736 26 formation formation NN cord-022526-j9kg00qf 1736 27 in in IN cord-022526-j9kg00qf 1736 28 the the DT cord-022526-j9kg00qf 1736 29 microvasculature microvasculature NN cord-022526-j9kg00qf 1736 30 . . . cord-022526-j9kg00qf 1737 1 If if IN cord-022526-j9kg00qf 1737 2 the the DT cord-022526-j9kg00qf 1737 3 basement basement NN cord-022526-j9kg00qf 1737 4 membrane membrane NN cord-022526-j9kg00qf 1737 5 and and CC cord-022526-j9kg00qf 1737 6 underlying underlying JJ cord-022526-j9kg00qf 1737 7 matrix matrix NN cord-022526-j9kg00qf 1737 8 are be VBP cord-022526-j9kg00qf 1737 9 compromised compromise VBN cord-022526-j9kg00qf 1737 10 , , , cord-022526-j9kg00qf 1737 11 further further JJ cord-022526-j9kg00qf 1737 12 microvascular microvascular JJ cord-022526-j9kg00qf 1737 13 hemorrhage hemorrhage NN cord-022526-j9kg00qf 1737 14 can can MD cord-022526-j9kg00qf 1737 15 occur occur VB cord-022526-j9kg00qf 1737 16 . . . cord-022526-j9kg00qf 1738 1 Endothelial endothelial JJ cord-022526-j9kg00qf 1738 2 cell cell NN cord-022526-j9kg00qf 1738 3 damage damage NN cord-022526-j9kg00qf 1738 4 is be VBZ cord-022526-j9kg00qf 1738 5 primarily primarily RB cord-022526-j9kg00qf 1738 6 neutrophilmediated neutrophilmediate VBN cord-022526-j9kg00qf 1738 7 . . . cord-022526-j9kg00qf 1739 1 More more RBR cord-022526-j9kg00qf 1739 2 specifically specifically RB cord-022526-j9kg00qf 1739 3 , , , cord-022526-j9kg00qf 1739 4 damage damage NN cord-022526-j9kg00qf 1739 5 is be VBZ cord-022526-j9kg00qf 1739 6 caused cause VBN cord-022526-j9kg00qf 1739 7 by by IN cord-022526-j9kg00qf 1739 8 oxygen oxygen NN cord-022526-j9kg00qf 1739 9 - - HYPH cord-022526-j9kg00qf 1739 10 derived derive VBN cord-022526-j9kg00qf 1739 11 free free JJ cord-022526-j9kg00qf 1739 12 radicals radical NNS cord-022526-j9kg00qf 1739 13 , , , cord-022526-j9kg00qf 1739 14 which which WDT cord-022526-j9kg00qf 1739 15 are be VBP cord-022526-j9kg00qf 1739 16 produced produce VBN cord-022526-j9kg00qf 1739 17 within within IN cord-022526-j9kg00qf 1739 18 endothelial endothelial JJ cord-022526-j9kg00qf 1739 19 cells cell NNS cord-022526-j9kg00qf 1739 20 via via IN cord-022526-j9kg00qf 1739 21 reactions reaction NNS cord-022526-j9kg00qf 1739 22 involving involve VBG cord-022526-j9kg00qf 1739 23 neutrophil neutrophil NN cord-022526-j9kg00qf 1739 24 - - HYPH cord-022526-j9kg00qf 1739 25 derived derive VBN cord-022526-j9kg00qf 1739 26 elastase elastase NN cord-022526-j9kg00qf 1739 27 and and CC cord-022526-j9kg00qf 1739 28 hydrogen hydrogen NN cord-022526-j9kg00qf 1739 29 peroxide peroxide NN cord-022526-j9kg00qf 1739 30 molecules molecule NNS cord-022526-j9kg00qf 1739 31 , , , cord-022526-j9kg00qf 1739 32 endothelial endothelial JJ cord-022526-j9kg00qf 1739 33 cell cell NN cord-022526-j9kg00qf 1739 34 enzymes enzyme NNS cord-022526-j9kg00qf 1739 35 such such JJ cord-022526-j9kg00qf 1739 36 as as IN cord-022526-j9kg00qf 1739 37 xanthine xanthine NN cord-022526-j9kg00qf 1739 38 oxidase oxidase NN cord-022526-j9kg00qf 1739 39 , , , cord-022526-j9kg00qf 1739 40 and and CC cord-022526-j9kg00qf 1739 41 endothelial endothelial JJ cord-022526-j9kg00qf 1739 42 cytosolic cytosolic JJ cord-022526-j9kg00qf 1739 43 iron iron NN cord-022526-j9kg00qf 1739 44 . . . cord-022526-j9kg00qf 1740 1 The the DT cord-022526-j9kg00qf 1740 2 hypochloric hypochloric JJ cord-022526-j9kg00qf 1740 3 anion anion NN cord-022526-j9kg00qf 1740 4 radical radical JJ cord-022526-j9kg00qf 1740 5 ( ( -LRB- cord-022526-j9kg00qf 1740 6 HO˙ HO˙ NNP cord-022526-j9kg00qf 1740 7 ) ) -RRB- cord-022526-j9kg00qf 1740 8 is be VBZ cord-022526-j9kg00qf 1740 9 thought think VBN cord-022526-j9kg00qf 1740 10 to to TO cord-022526-j9kg00qf 1740 11 be be VB cord-022526-j9kg00qf 1740 12 responsible responsible JJ cord-022526-j9kg00qf 1740 13 most most RBS cord-022526-j9kg00qf 1740 14 directly directly RB cord-022526-j9kg00qf 1740 15 for for IN cord-022526-j9kg00qf 1740 16 endothelial endothelial JJ cord-022526-j9kg00qf 1740 17 cell cell NN cord-022526-j9kg00qf 1740 18 cytotoxicity cytotoxicity NN cord-022526-j9kg00qf 1740 19 . . . cord-022526-j9kg00qf 1741 1 NO˙produced no˙produce VBN cord-022526-j9kg00qf 1741 2 by by IN cord-022526-j9kg00qf 1742 1 constitutively constitutively RB cord-022526-j9kg00qf 1742 2 expressed express VBD cord-022526-j9kg00qf 1742 3 nitric nitric JJ cord-022526-j9kg00qf 1742 4 oxide oxide NN cord-022526-j9kg00qf 1742 5 synthase synthase NN cord-022526-j9kg00qf 1742 6 in in IN cord-022526-j9kg00qf 1742 7 endothelial endothelial JJ cord-022526-j9kg00qf 1742 8 cells cell NNS cord-022526-j9kg00qf 1742 9 may may MD cord-022526-j9kg00qf 1742 10 afford afford VB cord-022526-j9kg00qf 1742 11 protection protection NN cord-022526-j9kg00qf 1742 12 from from IN cord-022526-j9kg00qf 1742 13 oxygen oxygen NN cord-022526-j9kg00qf 1742 14 radical radical JJ cord-022526-j9kg00qf 1742 15 - - HYPH cord-022526-j9kg00qf 1742 16 induced induce VBN cord-022526-j9kg00qf 1742 17 endothelial endothelial JJ cord-022526-j9kg00qf 1742 18 cell cell NN cord-022526-j9kg00qf 1742 19 damage damage NN cord-022526-j9kg00qf 1742 20 . . . cord-022526-j9kg00qf 1743 1 NO no UH cord-022526-j9kg00qf 1743 2 is be VBZ cord-022526-j9kg00qf 1743 3 able able JJ cord-022526-j9kg00qf 1743 4 to to TO cord-022526-j9kg00qf 1743 5 scavenge scavenge VB cord-022526-j9kg00qf 1743 6 superoxide superoxide NN cord-022526-j9kg00qf 1743 7 radicals radical NNS cord-022526-j9kg00qf 1743 8 and and CC cord-022526-j9kg00qf 1743 9 react react VB cord-022526-j9kg00qf 1743 10 with with IN cord-022526-j9kg00qf 1743 11 them -PRON- PRP cord-022526-j9kg00qf 1743 12 to to TO cord-022526-j9kg00qf 1743 13 form form VB cord-022526-j9kg00qf 1743 14 peroxynitrite peroxynitrite NN cord-022526-j9kg00qf 1743 15 . . . cord-022526-j9kg00qf 1744 1 Variations variation NNS cord-022526-j9kg00qf 1744 2 in in IN cord-022526-j9kg00qf 1744 3 the the DT cord-022526-j9kg00qf 1744 4 ability ability NN cord-022526-j9kg00qf 1744 5 to to TO cord-022526-j9kg00qf 1744 6 produce produce VB cord-022526-j9kg00qf 1744 7 NO no DT cord-022526-j9kg00qf 1744 8 may may MD cord-022526-j9kg00qf 1744 9 explain explain VB cord-022526-j9kg00qf 1744 10 why why WRB cord-022526-j9kg00qf 1744 11 vascular vascular JJ cord-022526-j9kg00qf 1744 12 beds bed NNS cord-022526-j9kg00qf 1744 13 in in IN cord-022526-j9kg00qf 1744 14 different different JJ cord-022526-j9kg00qf 1744 15 organs organ NNS cord-022526-j9kg00qf 1744 16 vary vary VBP cord-022526-j9kg00qf 1744 17 in in IN cord-022526-j9kg00qf 1744 18 their -PRON- PRP$ cord-022526-j9kg00qf 1744 19 susceptibility susceptibility NN cord-022526-j9kg00qf 1744 20 to to IN cord-022526-j9kg00qf 1744 21 neutrophilmediated neutrophilmediated JJ cord-022526-j9kg00qf 1744 22 damage damage NN cord-022526-j9kg00qf 1744 23 . . . cord-022526-j9kg00qf 1745 1 66 66 CD cord-022526-j9kg00qf 1745 2 Excessive excessive JJ cord-022526-j9kg00qf 1745 3 production production NN cord-022526-j9kg00qf 1745 4 of of IN cord-022526-j9kg00qf 1745 5 NO no NN cord-022526-j9kg00qf 1745 6 by by IN cord-022526-j9kg00qf 1745 7 an an DT cord-022526-j9kg00qf 1745 8 inducible inducible JJ cord-022526-j9kg00qf 1745 9 form form NN cord-022526-j9kg00qf 1745 10 of of IN cord-022526-j9kg00qf 1745 11 nitric nitric NN cord-022526-j9kg00qf 1745 12 oxide oxide NN cord-022526-j9kg00qf 1745 13 synthase synthase NN cord-022526-j9kg00qf 1745 14 ( ( -LRB- cord-022526-j9kg00qf 1745 15 i i NNP cord-022526-j9kg00qf 1745 16 NOS NOS NNP cord-022526-j9kg00qf 1745 17 ) ) -RRB- cord-022526-j9kg00qf 1745 18 , , , cord-022526-j9kg00qf 1745 19 however however RB cord-022526-j9kg00qf 1745 20 , , , cord-022526-j9kg00qf 1745 21 contributes contribute VBZ cord-022526-j9kg00qf 1745 22 to to IN cord-022526-j9kg00qf 1745 23 tissue tissue NN cord-022526-j9kg00qf 1745 24 damage damage NN cord-022526-j9kg00qf 1745 25 , , , cord-022526-j9kg00qf 1745 26 and and CC cord-022526-j9kg00qf 1745 27 increased increase VBN cord-022526-j9kg00qf 1745 28 peroxynitrite peroxynitrite JJ cord-022526-j9kg00qf 1745 29 concentrations concentration NNS cord-022526-j9kg00qf 1745 30 may may MD cord-022526-j9kg00qf 1745 31 be be VB cord-022526-j9kg00qf 1745 32 responsible responsible JJ cord-022526-j9kg00qf 1745 33 in in IN cord-022526-j9kg00qf 1745 34 part part NN cord-022526-j9kg00qf 1745 35 for for IN cord-022526-j9kg00qf 1745 36 PAF PAF NNP cord-022526-j9kg00qf 1745 37 - - HYPH cord-022526-j9kg00qf 1745 38 induced induce VBN cord-022526-j9kg00qf 1745 39 increases increase NNS cord-022526-j9kg00qf 1745 40 in in IN cord-022526-j9kg00qf 1745 41 vascular vascular JJ cord-022526-j9kg00qf 1745 42 permeability permeability NN cord-022526-j9kg00qf 1745 43 . . . cord-022526-j9kg00qf 1746 1 67 67 CD cord-022526-j9kg00qf 1747 1 In in IN cord-022526-j9kg00qf 1747 2 addition addition NN cord-022526-j9kg00qf 1747 3 to to IN cord-022526-j9kg00qf 1747 4 oxygen oxygen NN cord-022526-j9kg00qf 1747 5 - - HYPH cord-022526-j9kg00qf 1747 6 derived derive VBN cord-022526-j9kg00qf 1747 7 free free JJ cord-022526-j9kg00qf 1747 8 radicals radical NNS cord-022526-j9kg00qf 1747 9 , , , cord-022526-j9kg00qf 1747 10 activated activate VBN cord-022526-j9kg00qf 1747 11 neutrophils neutrophil NNS cord-022526-j9kg00qf 1747 12 release release NN cord-022526-j9kg00qf 1747 13 matrix matrix NN cord-022526-j9kg00qf 1747 14 metalloproteinases metalloproteinase NNS cord-022526-j9kg00qf 1747 15 , , , cord-022526-j9kg00qf 1747 16 which which WDT cord-022526-j9kg00qf 1747 17 contribute contribute VBP cord-022526-j9kg00qf 1747 18 to to IN cord-022526-j9kg00qf 1747 19 tissue tissue NN cord-022526-j9kg00qf 1747 20 damage damage NN cord-022526-j9kg00qf 1747 21 . . . cord-022526-j9kg00qf 1748 1 56 56 CD cord-022526-j9kg00qf 1748 2 Vascular vascular JJ cord-022526-j9kg00qf 1748 3 endothelial endothelial JJ cord-022526-j9kg00qf 1748 4 cells cell NNS cord-022526-j9kg00qf 1748 5 are be VBP cord-022526-j9kg00qf 1748 6 further further RB cord-022526-j9kg00qf 1748 7 susceptible susceptible JJ cord-022526-j9kg00qf 1748 8 to to IN cord-022526-j9kg00qf 1748 9 direct direct JJ cord-022526-j9kg00qf 1748 10 effects effect NNS cord-022526-j9kg00qf 1748 11 of of IN cord-022526-j9kg00qf 1748 12 various various JJ cord-022526-j9kg00qf 1748 13 cytokines cytokine NNS cord-022526-j9kg00qf 1748 14 , , , cord-022526-j9kg00qf 1748 15 most most RBS cord-022526-j9kg00qf 1748 16 prominently prominently RB cord-022526-j9kg00qf 1748 17 TNF TNF NNP cord-022526-j9kg00qf 1748 18 - - HYPH cord-022526-j9kg00qf 1748 19 α α NNP cord-022526-j9kg00qf 1748 20 and and CC cord-022526-j9kg00qf 1748 21 IL-1 IL-1 NNP cord-022526-j9kg00qf 1748 22 . . . cord-022526-j9kg00qf 1749 1 These these DT cord-022526-j9kg00qf 1749 2 cytokines cytokine NNS cord-022526-j9kg00qf 1749 3 are be VBP cord-022526-j9kg00qf 1749 4 thought think VBN cord-022526-j9kg00qf 1749 5 to to TO cord-022526-j9kg00qf 1749 6 cause cause VB cord-022526-j9kg00qf 1749 7 damage damage NN cord-022526-j9kg00qf 1749 8 via via IN cord-022526-j9kg00qf 1749 9 the the DT cord-022526-j9kg00qf 1749 10 induction induction NN cord-022526-j9kg00qf 1749 11 of of IN cord-022526-j9kg00qf 1749 12 COX COX NNP cord-022526-j9kg00qf 1749 13 activity activity NN cord-022526-j9kg00qf 1749 14 and and CC cord-022526-j9kg00qf 1749 15 production production NN cord-022526-j9kg00qf 1749 16 of of IN cord-022526-j9kg00qf 1749 17 prostanoids prostanoid NNS cord-022526-j9kg00qf 1749 18 and and CC cord-022526-j9kg00qf 1749 19 through through IN cord-022526-j9kg00qf 1749 20 generation generation NN cord-022526-j9kg00qf 1749 21 of of IN cord-022526-j9kg00qf 1749 22 free free JJ cord-022526-j9kg00qf 1749 23 radicals radical NNS cord-022526-j9kg00qf 1749 24 . . . cord-022526-j9kg00qf 1750 1 Neutrophil Neutrophil NNP cord-022526-j9kg00qf 1750 2 activation activation NN cord-022526-j9kg00qf 1750 3 by by IN cord-022526-j9kg00qf 1750 4 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1750 5 and and CC cord-022526-j9kg00qf 1750 6 cytokines cytokine NNS cord-022526-j9kg00qf 1750 7 results result NNS cord-022526-j9kg00qf 1750 8 in in IN cord-022526-j9kg00qf 1750 9 stimulation stimulation NN cord-022526-j9kg00qf 1750 10 of of IN cord-022526-j9kg00qf 1750 11 phagocytosis phagocytosis NN cord-022526-j9kg00qf 1750 12 and and CC cord-022526-j9kg00qf 1750 13 the the DT cord-022526-j9kg00qf 1750 14 respiratory respiratory JJ cord-022526-j9kg00qf 1750 15 burst burst NN cord-022526-j9kg00qf 1750 16 , , , cord-022526-j9kg00qf 1750 17 release release NN cord-022526-j9kg00qf 1750 18 of of IN cord-022526-j9kg00qf 1750 19 lysosomal lysosomal JJ cord-022526-j9kg00qf 1750 20 enzymes enzyme NNS cord-022526-j9kg00qf 1750 21 and and CC cord-022526-j9kg00qf 1750 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 1750 23 mediators mediator NNS cord-022526-j9kg00qf 1750 24 , , , cord-022526-j9kg00qf 1750 25 and and CC cord-022526-j9kg00qf 1750 26 expression expression NN cord-022526-j9kg00qf 1750 27 of of IN cord-022526-j9kg00qf 1750 28 adhesion adhesion NN cord-022526-j9kg00qf 1750 29 molecules molecule NNS cord-022526-j9kg00qf 1750 30 . . . cord-022526-j9kg00qf 1751 1 Perhaps perhaps RB cord-022526-j9kg00qf 1751 2 the the DT cord-022526-j9kg00qf 1751 3 single single JJ cord-022526-j9kg00qf 1751 4 most most RBS cord-022526-j9kg00qf 1751 5 specific specific JJ cord-022526-j9kg00qf 1751 6 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 1751 7 indicator indicator NN cord-022526-j9kg00qf 1751 8 of of IN cord-022526-j9kg00qf 1751 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1751 10 is be VBZ cord-022526-j9kg00qf 1751 11 pronounced pronounce VBN cord-022526-j9kg00qf 1751 12 neutropenia neutropenia NN cord-022526-j9kg00qf 1751 13 , , , cord-022526-j9kg00qf 1751 14 68 68 CD cord-022526-j9kg00qf 1751 15 which which WDT cord-022526-j9kg00qf 1751 16 temporally temporally RB cord-022526-j9kg00qf 1751 17 correlates correlate VBZ cord-022526-j9kg00qf 1751 18 with with IN cord-022526-j9kg00qf 1751 19 peak peak NN cord-022526-j9kg00qf 1751 20 plasma plasma NN cord-022526-j9kg00qf 1751 21 concentrations concentration NNS cord-022526-j9kg00qf 1751 22 of of IN cord-022526-j9kg00qf 1751 23 TNF TNF NNP cord-022526-j9kg00qf 1751 24 . . . cord-022526-j9kg00qf 1752 1 69 69 CD cord-022526-j9kg00qf 1753 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 1753 2 is be VBZ cord-022526-j9kg00qf 1753 3 caused cause VBN cord-022526-j9kg00qf 1753 4 primarily primarily RB cord-022526-j9kg00qf 1753 5 by by IN cord-022526-j9kg00qf 1753 6 margination margination NN cord-022526-j9kg00qf 1753 7 of of IN cord-022526-j9kg00qf 1753 8 neutrophils neutrophil NNS cord-022526-j9kg00qf 1753 9 in in IN cord-022526-j9kg00qf 1753 10 the the DT cord-022526-j9kg00qf 1753 11 vasculature vasculature NN cord-022526-j9kg00qf 1753 12 , , , cord-022526-j9kg00qf 1753 13 whereas whereas IN cord-022526-j9kg00qf 1753 14 significant significant JJ cord-022526-j9kg00qf 1753 15 loss loss NN cord-022526-j9kg00qf 1753 16 through through IN cord-022526-j9kg00qf 1753 17 active active JJ cord-022526-j9kg00qf 1753 18 migration migration NN cord-022526-j9kg00qf 1753 19 into into IN cord-022526-j9kg00qf 1753 20 peripheral peripheral JJ cord-022526-j9kg00qf 1753 21 tissues tissue NNS cord-022526-j9kg00qf 1753 22 likely likely RB cord-022526-j9kg00qf 1753 23 is be VBZ cord-022526-j9kg00qf 1753 24 limited limit VBN cord-022526-j9kg00qf 1753 25 to to IN cord-022526-j9kg00qf 1753 26 the the DT cord-022526-j9kg00qf 1753 27 presence presence NN cord-022526-j9kg00qf 1753 28 of of IN cord-022526-j9kg00qf 1753 29 a a DT cord-022526-j9kg00qf 1753 30 localized localized JJ cord-022526-j9kg00qf 1753 31 source source NN cord-022526-j9kg00qf 1753 32 of of IN cord-022526-j9kg00qf 1753 33 infection infection NN cord-022526-j9kg00qf 1753 34 . . . cord-022526-j9kg00qf 1754 1 Margination Margination NNP cord-022526-j9kg00qf 1754 2 is be VBZ cord-022526-j9kg00qf 1754 3 made make VBN cord-022526-j9kg00qf 1754 4 possible possible JJ cord-022526-j9kg00qf 1754 5 by by IN cord-022526-j9kg00qf 1754 6 adhesion adhesion NN cord-022526-j9kg00qf 1754 7 molecules molecule NNS cord-022526-j9kg00qf 1754 8 on on IN cord-022526-j9kg00qf 1754 9 endothelial endothelial JJ cord-022526-j9kg00qf 1754 10 cells cell NNS cord-022526-j9kg00qf 1754 11 and and CC cord-022526-j9kg00qf 1754 12 leukocytes leukocyte NNS cord-022526-j9kg00qf 1754 13 that that WDT cord-022526-j9kg00qf 1754 14 interact interact VBP cord-022526-j9kg00qf 1754 15 and and CC cord-022526-j9kg00qf 1754 16 allow allow VBP cord-022526-j9kg00qf 1754 17 sticking sticking NN cord-022526-j9kg00qf 1754 18 of of IN cord-022526-j9kg00qf 1754 19 leukocytes leukocyte NNS cord-022526-j9kg00qf 1754 20 to to IN cord-022526-j9kg00qf 1754 21 the the DT cord-022526-j9kg00qf 1754 22 endothelial endothelial JJ cord-022526-j9kg00qf 1754 23 lining lining NN cord-022526-j9kg00qf 1754 24 of of IN cord-022526-j9kg00qf 1754 25 blood blood NN cord-022526-j9kg00qf 1754 26 vessels vessel NNS cord-022526-j9kg00qf 1754 27 . . . cord-022526-j9kg00qf 1755 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1755 2 or or CC cord-022526-j9kg00qf 1755 3 cytokines cytokine NNS cord-022526-j9kg00qf 1755 4 such such JJ cord-022526-j9kg00qf 1755 5 as as IN cord-022526-j9kg00qf 1755 6 TNF TNF NNP cord-022526-j9kg00qf 1755 7 and and CC cord-022526-j9kg00qf 1755 8 IL-1 IL-1 NNP cord-022526-j9kg00qf 1755 9 can can MD cord-022526-j9kg00qf 1755 10 initiate initiate VB cord-022526-j9kg00qf 1755 11 expression expression NN cord-022526-j9kg00qf 1755 12 of of IN cord-022526-j9kg00qf 1755 13 adhesion adhesion NN cord-022526-j9kg00qf 1755 14 molecules molecule NNS cord-022526-j9kg00qf 1755 15 . . . cord-022526-j9kg00qf 1756 1 70 70 CD cord-022526-j9kg00qf 1756 2 Subsequent subsequent JJ cord-022526-j9kg00qf 1756 3 transmigration transmigration NN cord-022526-j9kg00qf 1756 4 of of IN cord-022526-j9kg00qf 1756 5 cells cell NNS cord-022526-j9kg00qf 1756 6 into into IN cord-022526-j9kg00qf 1756 7 tissue tissue NN cord-022526-j9kg00qf 1756 8 spaces space NNS cord-022526-j9kg00qf 1756 9 is be VBZ cord-022526-j9kg00qf 1756 10 aided aid VBN cord-022526-j9kg00qf 1756 11 by by IN cord-022526-j9kg00qf 1756 12 the the DT cord-022526-j9kg00qf 1756 13 production production NN cord-022526-j9kg00qf 1756 14 of of IN cord-022526-j9kg00qf 1756 15 leukocyte leukocyte NN cord-022526-j9kg00qf 1756 16 collagenase collagenase NNP cord-022526-j9kg00qf 1756 17 , , , cord-022526-j9kg00qf 1756 18 which which WDT cord-022526-j9kg00qf 1756 19 allows allow VBZ cord-022526-j9kg00qf 1756 20 enzymatic enzymatic JJ cord-022526-j9kg00qf 1756 21 destruction destruction NN cord-022526-j9kg00qf 1756 22 of of IN cord-022526-j9kg00qf 1756 23 the the DT cord-022526-j9kg00qf 1756 24 vascular vascular JJ cord-022526-j9kg00qf 1756 25 basement basement NN cord-022526-j9kg00qf 1756 26 membrane membrane NN cord-022526-j9kg00qf 1756 27 . . . cord-022526-j9kg00qf 1757 1 Margination margination NN cord-022526-j9kg00qf 1757 2 and and CC cord-022526-j9kg00qf 1757 3 transmigration transmigration NN cord-022526-j9kg00qf 1757 4 of of IN cord-022526-j9kg00qf 1757 5 neutrophils neutrophil NNS cord-022526-j9kg00qf 1757 6 occurs occur VBZ cord-022526-j9kg00qf 1757 7 in in IN cord-022526-j9kg00qf 1757 8 three three CD cord-022526-j9kg00qf 1757 9 phases phase NNS cord-022526-j9kg00qf 1757 10 . . . cord-022526-j9kg00qf 1758 1 70 70 CD cord-022526-j9kg00qf 1758 2 , , , cord-022526-j9kg00qf 1758 3 71 71 CD cord-022526-j9kg00qf 1759 1 In in IN cord-022526-j9kg00qf 1759 2 the the DT cord-022526-j9kg00qf 1759 3 first first JJ cord-022526-j9kg00qf 1759 4 phase phase NN cord-022526-j9kg00qf 1759 5 of of IN cord-022526-j9kg00qf 1759 6 tethering tethering NN cord-022526-j9kg00qf 1759 7 and and CC cord-022526-j9kg00qf 1759 8 rolling rolling NN cord-022526-j9kg00qf 1759 9 , , , cord-022526-j9kg00qf 1759 10 endothelial endothelial JJ cord-022526-j9kg00qf 1759 11 cells cell NNS cord-022526-j9kg00qf 1759 12 are be VBP cord-022526-j9kg00qf 1759 13 stimulated stimulate VBN cord-022526-j9kg00qf 1759 14 to to TO cord-022526-j9kg00qf 1759 15 express express VB cord-022526-j9kg00qf 1759 16 P p NN cord-022526-j9kg00qf 1759 17 - - HYPH cord-022526-j9kg00qf 1759 18 selectin selectin NNP cord-022526-j9kg00qf 1759 19 and and CC cord-022526-j9kg00qf 1759 20 E e NN cord-022526-j9kg00qf 1759 21 - - NN cord-022526-j9kg00qf 1759 22 selectin selectin NNP cord-022526-j9kg00qf 1759 23 , , , cord-022526-j9kg00qf 1759 24 which which WDT cord-022526-j9kg00qf 1759 25 bind bind VBP cord-022526-j9kg00qf 1759 26 to to IN cord-022526-j9kg00qf 1759 27 P p NN cord-022526-j9kg00qf 1759 28 - - HYPH cord-022526-j9kg00qf 1759 29 selectin selectin NN cord-022526-j9kg00qf 1759 30 glycoprotein glycoprotein NN cord-022526-j9kg00qf 1759 31 ligand-1 ligand-1 NNP cord-022526-j9kg00qf 1759 32 and and CC cord-022526-j9kg00qf 1759 33 sialylated sialylate VBN cord-022526-j9kg00qf 1759 34 Lewis Lewis NNP cord-022526-j9kg00qf 1759 35 - - HYPH cord-022526-j9kg00qf 1759 36 X X NNP cord-022526-j9kg00qf 1759 37 - - HYPH cord-022526-j9kg00qf 1759 38 like like JJ cord-022526-j9kg00qf 1759 39 structures structure NNS cord-022526-j9kg00qf 1759 40 on on IN cord-022526-j9kg00qf 1759 41 leukocytes leukocyte NNS cord-022526-j9kg00qf 1759 42 , , , cord-022526-j9kg00qf 1759 43 respectively respectively RB cord-022526-j9kg00qf 1759 44 . . . cord-022526-j9kg00qf 1760 1 Whereas whereas IN cord-022526-j9kg00qf 1760 2 P p NN cord-022526-j9kg00qf 1760 3 - - HYPH cord-022526-j9kg00qf 1760 4 selectin selectin NNP cord-022526-j9kg00qf 1760 5 is be VBZ cord-022526-j9kg00qf 1760 6 stored store VBN cord-022526-j9kg00qf 1760 7 preformed preformed JJ cord-022526-j9kg00qf 1760 8 in in IN cord-022526-j9kg00qf 1760 9 Weibel Weibel NNP cord-022526-j9kg00qf 1760 10 - - HYPH cord-022526-j9kg00qf 1760 11 Palade Palade NNP cord-022526-j9kg00qf 1760 12 bodies body NNS cord-022526-j9kg00qf 1760 13 of of IN cord-022526-j9kg00qf 1760 14 endothelial endothelial JJ cord-022526-j9kg00qf 1760 15 cells cell NNS cord-022526-j9kg00qf 1760 16 , , , cord-022526-j9kg00qf 1760 17 E e NN cord-022526-j9kg00qf 1760 18 - - NN cord-022526-j9kg00qf 1760 19 selectin selectin NNP cord-022526-j9kg00qf 1760 20 is be VBZ cord-022526-j9kg00qf 1760 21 expressed express VBN cord-022526-j9kg00qf 1760 22 only only RB cord-022526-j9kg00qf 1760 23 following follow VBG cord-022526-j9kg00qf 1760 24 stimulation stimulation NN cord-022526-j9kg00qf 1760 25 by by IN cord-022526-j9kg00qf 1760 26 cytokines cytokine NNS cord-022526-j9kg00qf 1760 27 . . . cord-022526-j9kg00qf 1761 1 Additionally additionally RB cord-022526-j9kg00qf 1761 2 , , , cord-022526-j9kg00qf 1761 3 constitutively constitutively RB cord-022526-j9kg00qf 1761 4 expressed express VBD cord-022526-j9kg00qf 1761 5 L l NN cord-022526-j9kg00qf 1761 6 - - HYPH cord-022526-j9kg00qf 1761 7 selectin selectin NNP cord-022526-j9kg00qf 1761 8 on on IN cord-022526-j9kg00qf 1761 9 neutrophils neutrophil NNS cord-022526-j9kg00qf 1761 10 can can MD cord-022526-j9kg00qf 1761 11 bind bind VB cord-022526-j9kg00qf 1761 12 to to IN cord-022526-j9kg00qf 1761 13 endothelial endothelial JJ cord-022526-j9kg00qf 1761 14 glycoproteins glycoprotein NNS cord-022526-j9kg00qf 1761 15 and and CC cord-022526-j9kg00qf 1761 16 glycolipids glycolipid NNS cord-022526-j9kg00qf 1761 17 . . . cord-022526-j9kg00qf 1762 1 During during IN cord-022526-j9kg00qf 1762 2 the the DT cord-022526-j9kg00qf 1762 3 second second JJ cord-022526-j9kg00qf 1762 4 phase phase NN cord-022526-j9kg00qf 1762 5 , , , cord-022526-j9kg00qf 1762 6 firm firm JJ cord-022526-j9kg00qf 1762 7 adhesion adhesion NN cord-022526-j9kg00qf 1762 8 is be VBZ cord-022526-j9kg00qf 1762 9 mediated mediate VBN cord-022526-j9kg00qf 1762 10 by by IN cord-022526-j9kg00qf 1762 11 binding bind VBG cord-022526-j9kg00qf 1762 12 of of IN cord-022526-j9kg00qf 1762 13 neutrophil neutrophil NN cord-022526-j9kg00qf 1762 14 integrins integrin NNS cord-022526-j9kg00qf 1762 15 ( ( -LRB- cord-022526-j9kg00qf 1762 16 LFA-1 LFA-1 NNP cord-022526-j9kg00qf 1762 17 and and CC cord-022526-j9kg00qf 1762 18 Mac-1 Mac-1 NNP cord-022526-j9kg00qf 1762 19 , , , cord-022526-j9kg00qf 1762 20 also also RB cord-022526-j9kg00qf 1762 21 known know VBN cord-022526-j9kg00qf 1762 22 as as IN cord-022526-j9kg00qf 1762 23 CD11a CD11a NNS cord-022526-j9kg00qf 1762 24 / / SYM cord-022526-j9kg00qf 1762 25 CD18 CD18 NNP cord-022526-j9kg00qf 1762 26 and and CC cord-022526-j9kg00qf 1762 27 CD11b CD11b NNPS cord-022526-j9kg00qf 1762 28 / / SYM cord-022526-j9kg00qf 1762 29 CD18 CD18 NNP cord-022526-j9kg00qf 1762 30 ) ) -RRB- cord-022526-j9kg00qf 1762 31 to to IN cord-022526-j9kg00qf 1762 32 intercellular intercellular JJ cord-022526-j9kg00qf 1762 33 adhesion adhesion NN cord-022526-j9kg00qf 1762 34 molecule molecule NN cord-022526-j9kg00qf 1762 35 1 1 CD cord-022526-j9kg00qf 1762 36 ( ( -LRB- cord-022526-j9kg00qf 1762 37 an an DT cord-022526-j9kg00qf 1762 38 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 1762 39 structure structure NN cord-022526-j9kg00qf 1762 40 ) ) -RRB- cord-022526-j9kg00qf 1762 41 on on IN cord-022526-j9kg00qf 1762 42 endothelial endothelial JJ cord-022526-j9kg00qf 1762 43 cells cell NNS cord-022526-j9kg00qf 1762 44 . . . cord-022526-j9kg00qf 1763 1 Although although IN cord-022526-j9kg00qf 1763 2 integrins integrin NNS cord-022526-j9kg00qf 1763 3 are be VBP cord-022526-j9kg00qf 1763 4 expressed express VBN cord-022526-j9kg00qf 1763 5 constitutively constitutively RB cord-022526-j9kg00qf 1763 6 on on IN cord-022526-j9kg00qf 1763 7 the the DT cord-022526-j9kg00qf 1763 8 leukocyte leukocyte NN cord-022526-j9kg00qf 1763 9 surface surface NN cord-022526-j9kg00qf 1763 10 , , , cord-022526-j9kg00qf 1763 11 activation activation NN cord-022526-j9kg00qf 1763 12 signals signal NNS cord-022526-j9kg00qf 1763 13 are be VBP cord-022526-j9kg00qf 1763 14 necessary necessary JJ cord-022526-j9kg00qf 1763 15 to to TO cord-022526-j9kg00qf 1763 16 induce induce VB cord-022526-j9kg00qf 1763 17 a a DT cord-022526-j9kg00qf 1763 18 high high JJ cord-022526-j9kg00qf 1763 19 - - HYPH cord-022526-j9kg00qf 1763 20 affinity affinity NN cord-022526-j9kg00qf 1763 21 state state NN cord-022526-j9kg00qf 1763 22 and and CC cord-022526-j9kg00qf 1763 23 interaction interaction NN cord-022526-j9kg00qf 1763 24 with with IN cord-022526-j9kg00qf 1763 25 the the DT cord-022526-j9kg00qf 1763 26 endothelial endothelial JJ cord-022526-j9kg00qf 1763 27 surface surface NN cord-022526-j9kg00qf 1763 28 . . . cord-022526-j9kg00qf 1764 1 Transmigration transmigration NN cord-022526-j9kg00qf 1764 2 finally finally RB cord-022526-j9kg00qf 1764 3 requires require VBZ cord-022526-j9kg00qf 1764 4 the the DT cord-022526-j9kg00qf 1764 5 expression expression NN cord-022526-j9kg00qf 1764 6 of of IN cord-022526-j9kg00qf 1764 7 yet yet RB cord-022526-j9kg00qf 1764 8 another another DT cord-022526-j9kg00qf 1764 9 adhesion adhesion NN cord-022526-j9kg00qf 1764 10 molecule molecule NN cord-022526-j9kg00qf 1764 11 , , , cord-022526-j9kg00qf 1764 12 namely namely RB cord-022526-j9kg00qf 1764 13 platelet platelet NN cord-022526-j9kg00qf 1764 14 / / SYM cord-022526-j9kg00qf 1764 15 endothelial endothelial JJ cord-022526-j9kg00qf 1764 16 cell cell NN cord-022526-j9kg00qf 1764 17 adhesion adhesion NN cord-022526-j9kg00qf 1764 18 molecule molecule NN cord-022526-j9kg00qf 1764 19 1 1 CD cord-022526-j9kg00qf 1764 20 , , , cord-022526-j9kg00qf 1764 21 which which WDT cord-022526-j9kg00qf 1764 22 is be VBZ cord-022526-j9kg00qf 1764 23 located locate VBN cord-022526-j9kg00qf 1764 24 at at IN cord-022526-j9kg00qf 1764 25 the the DT cord-022526-j9kg00qf 1764 26 intercellular intercellular JJ cord-022526-j9kg00qf 1764 27 junction junction NN cord-022526-j9kg00qf 1764 28 of of IN cord-022526-j9kg00qf 1764 29 endothelial endothelial JJ cord-022526-j9kg00qf 1764 30 cells cell NNS cord-022526-j9kg00qf 1764 31 . . . cord-022526-j9kg00qf 1765 1 71 71 CD cord-022526-j9kg00qf 1765 2 Chemotactic Chemotactic NNP cord-022526-j9kg00qf 1765 3 factors factor NNS cord-022526-j9kg00qf 1765 4 including include VBG cord-022526-j9kg00qf 1765 5 activated activate VBN cord-022526-j9kg00qf 1765 6 complement complement NN cord-022526-j9kg00qf 1765 7 factor factor NN cord-022526-j9kg00qf 1765 8 C5a C5a NNS cord-022526-j9kg00qf 1765 9 and and CC cord-022526-j9kg00qf 1765 10 the the DT cord-022526-j9kg00qf 1765 11 CXC CXC NNP cord-022526-j9kg00qf 1765 12 chemokines chemokine NNS cord-022526-j9kg00qf 1765 13 control control NN cord-022526-j9kg00qf 1765 14 transmigration transmigration NN cord-022526-j9kg00qf 1765 15 . . . cord-022526-j9kg00qf 1766 1 66 66 CD cord-022526-j9kg00qf 1767 1 The the DT cord-022526-j9kg00qf 1767 2 latter latter JJ cord-022526-j9kg00qf 1767 3 group group NN cord-022526-j9kg00qf 1767 4 includes include VBZ cord-022526-j9kg00qf 1767 5 IL-8 IL-8 NNP cord-022526-j9kg00qf 1767 6 , , , cord-022526-j9kg00qf 1767 7 which which WDT cord-022526-j9kg00qf 1767 8 is be VBZ cord-022526-j9kg00qf 1767 9 expressed express VBN cord-022526-j9kg00qf 1767 10 by by IN cord-022526-j9kg00qf 1767 11 endothelial endothelial JJ cord-022526-j9kg00qf 1767 12 cells cell NNS cord-022526-j9kg00qf 1767 13 in in IN cord-022526-j9kg00qf 1767 14 response response NN cord-022526-j9kg00qf 1767 15 to to IN cord-022526-j9kg00qf 1767 16 activation activation NN cord-022526-j9kg00qf 1767 17 . . . cord-022526-j9kg00qf 1768 1 Rebound Rebound NNP cord-022526-j9kg00qf 1768 2 neutrophilia neutrophilia NNP cord-022526-j9kg00qf 1768 3 , , , cord-022526-j9kg00qf 1768 4 which which WDT cord-022526-j9kg00qf 1768 5 is be VBZ cord-022526-j9kg00qf 1768 6 observed observe VBN cord-022526-j9kg00qf 1768 7 frequently frequently RB cord-022526-j9kg00qf 1768 8 following follow VBG cord-022526-j9kg00qf 1768 9 episodes episode NNS cord-022526-j9kg00qf 1768 10 of of IN cord-022526-j9kg00qf 1768 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1768 12 , , , cord-022526-j9kg00qf 1768 13 is be VBZ cord-022526-j9kg00qf 1768 14 caused cause VBN cord-022526-j9kg00qf 1768 15 by by IN cord-022526-j9kg00qf 1768 16 neutrophil neutrophil NN cord-022526-j9kg00qf 1768 17 release release NN cord-022526-j9kg00qf 1768 18 from from IN cord-022526-j9kg00qf 1768 19 the the DT cord-022526-j9kg00qf 1768 20 bone bone NN cord-022526-j9kg00qf 1768 21 marrow marrow NN cord-022526-j9kg00qf 1768 22 reserve reserve NN cord-022526-j9kg00qf 1768 23 pool pool NN cord-022526-j9kg00qf 1768 24 and and CC cord-022526-j9kg00qf 1768 25 by by IN cord-022526-j9kg00qf 1768 26 stimulation stimulation NN cord-022526-j9kg00qf 1768 27 of of IN cord-022526-j9kg00qf 1768 28 myeloid myeloid JJ cord-022526-j9kg00qf 1768 29 cell cell NN cord-022526-j9kg00qf 1768 30 proliferation proliferation NN cord-022526-j9kg00qf 1768 31 via via IN cord-022526-j9kg00qf 1768 32 granulocyte granulocyte NN cord-022526-j9kg00qf 1768 33 - - HYPH cord-022526-j9kg00qf 1768 34 macrophage macrophage NN cord-022526-j9kg00qf 1768 35 colony colony NN cord-022526-j9kg00qf 1768 36 - - HYPH cord-022526-j9kg00qf 1768 37 stimulating stimulate VBG cord-022526-j9kg00qf 1768 38 factor factor NN cord-022526-j9kg00qf 1768 39 and and CC cord-022526-j9kg00qf 1768 40 is be VBZ cord-022526-j9kg00qf 1768 41 mediated mediate VBN cord-022526-j9kg00qf 1768 42 primarily primarily RB cord-022526-j9kg00qf 1768 43 by by IN cord-022526-j9kg00qf 1768 44 TNF TNF NNP cord-022526-j9kg00qf 1768 45 and and CC cord-022526-j9kg00qf 1768 46 IL-1 IL-1 NNP cord-022526-j9kg00qf 1768 47 . . . cord-022526-j9kg00qf 1769 1 54 54 CD cord-022526-j9kg00qf 1770 1 In in IN cord-022526-j9kg00qf 1770 2 health health NN cord-022526-j9kg00qf 1770 3 , , , cord-022526-j9kg00qf 1770 4 coagulation coagulation NN cord-022526-j9kg00qf 1770 5 and and CC cord-022526-j9kg00qf 1770 6 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 1770 7 underlie underlie VBP cord-022526-j9kg00qf 1770 8 stringent stringent JJ cord-022526-j9kg00qf 1770 9 control control NN cord-022526-j9kg00qf 1770 10 mechanisms mechanism NNS cord-022526-j9kg00qf 1770 11 that that WDT cord-022526-j9kg00qf 1770 12 allow allow VBP cord-022526-j9kg00qf 1770 13 appropriate appropriate JJ cord-022526-j9kg00qf 1770 14 clot clot NN cord-022526-j9kg00qf 1770 15 formation formation NN cord-022526-j9kg00qf 1770 16 and and CC cord-022526-j9kg00qf 1770 17 their -PRON- PRP$ cord-022526-j9kg00qf 1770 18 resolution resolution NN cord-022526-j9kg00qf 1770 19 . . . cord-022526-j9kg00qf 1771 1 Coagulopathies coagulopathie NNS cord-022526-j9kg00qf 1771 2 frequently frequently RB cord-022526-j9kg00qf 1771 3 are be VBP cord-022526-j9kg00qf 1771 4 observed observe VBN cord-022526-j9kg00qf 1771 5 in in IN cord-022526-j9kg00qf 1771 6 horses horse NNS cord-022526-j9kg00qf 1771 7 with with IN cord-022526-j9kg00qf 1771 8 colic colic NN cord-022526-j9kg00qf 1771 9 16 16 CD cord-022526-j9kg00qf 1771 10 , , , cord-022526-j9kg00qf 1771 11 72 72 CD cord-022526-j9kg00qf 1771 12 , , , cord-022526-j9kg00qf 1771 13 73 73 CD cord-022526-j9kg00qf 1771 14 and and CC cord-022526-j9kg00qf 1771 15 foals foal NNS cord-022526-j9kg00qf 1771 16 with with IN cord-022526-j9kg00qf 1771 17 sepsis sepsis NN cord-022526-j9kg00qf 1771 18 11 11 CD cord-022526-j9kg00qf 1771 19 and and CC cord-022526-j9kg00qf 1771 20 are be VBP cord-022526-j9kg00qf 1771 21 likely likely RB cord-022526-j9kg00qf 1771 22 attributable attributable JJ cord-022526-j9kg00qf 1771 23 to to IN cord-022526-j9kg00qf 1771 24 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1771 25 . . . cord-022526-j9kg00qf 1772 1 Disseminated disseminate VBN cord-022526-j9kg00qf 1772 2 intravascular intravascular JJ cord-022526-j9kg00qf 1772 3 coagulation coagulation NN cord-022526-j9kg00qf 1772 4 ( ( -LRB- cord-022526-j9kg00qf 1772 5 DIC DIC NNP cord-022526-j9kg00qf 1772 6 ) ) -RRB- cord-022526-j9kg00qf 1772 7 results result VBZ cord-022526-j9kg00qf 1772 8 from from IN cord-022526-j9kg00qf 1772 9 a a DT cord-022526-j9kg00qf 1772 10 widespread widespread JJ cord-022526-j9kg00qf 1772 11 activation activation NN cord-022526-j9kg00qf 1772 12 of of IN cord-022526-j9kg00qf 1772 13 the the DT cord-022526-j9kg00qf 1772 14 coagulation coagulation NN cord-022526-j9kg00qf 1772 15 and and CC cord-022526-j9kg00qf 1772 16 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 1772 17 systems system NNS cord-022526-j9kg00qf 1772 18 and and CC cord-022526-j9kg00qf 1772 19 failure failure NN cord-022526-j9kg00qf 1772 20 of of IN cord-022526-j9kg00qf 1772 21 their -PRON- PRP$ cord-022526-j9kg00qf 1772 22 control control NN cord-022526-j9kg00qf 1772 23 mechanisms mechanism NNS cord-022526-j9kg00qf 1772 24 . . . cord-022526-j9kg00qf 1773 1 Ultimately ultimately RB cord-022526-j9kg00qf 1773 2 , , , cord-022526-j9kg00qf 1773 3 this this DT cord-022526-j9kg00qf 1773 4 leads lead VBZ cord-022526-j9kg00qf 1773 5 to to IN cord-022526-j9kg00qf 1773 6 disseminated disseminate VBN cord-022526-j9kg00qf 1773 7 fibrin fibrin NN cord-022526-j9kg00qf 1773 8 deposition deposition NN cord-022526-j9kg00qf 1773 9 in in IN cord-022526-j9kg00qf 1773 10 the the DT cord-022526-j9kg00qf 1773 11 microvasculature microvasculature NN cord-022526-j9kg00qf 1773 12 , , , cord-022526-j9kg00qf 1773 13 consumption consumption NN cord-022526-j9kg00qf 1773 14 of of IN cord-022526-j9kg00qf 1773 15 platelets platelet NNS cord-022526-j9kg00qf 1773 16 and and CC cord-022526-j9kg00qf 1773 17 clotting clotting NN cord-022526-j9kg00qf 1773 18 factors factor NNS cord-022526-j9kg00qf 1773 19 , , , cord-022526-j9kg00qf 1773 20 and and CC cord-022526-j9kg00qf 1773 21 accumulation accumulation NN cord-022526-j9kg00qf 1773 22 of of IN cord-022526-j9kg00qf 1773 23 fibrin fibrin NN cord-022526-j9kg00qf 1773 24 degradation degradation NN cord-022526-j9kg00qf 1773 25 products product NNS cord-022526-j9kg00qf 1773 26 ( ( -LRB- cord-022526-j9kg00qf 1773 27 FDPs FDPs NNP cord-022526-j9kg00qf 1773 28 ) ) -RRB- cord-022526-j9kg00qf 1773 29 . . . cord-022526-j9kg00qf 1774 1 Depending depend VBG cord-022526-j9kg00qf 1774 2 on on IN cord-022526-j9kg00qf 1774 3 the the DT cord-022526-j9kg00qf 1774 4 underlying underlie VBG cord-022526-j9kg00qf 1774 5 disease disease NN cord-022526-j9kg00qf 1774 6 process process NN cord-022526-j9kg00qf 1774 7 and and CC cord-022526-j9kg00qf 1774 8 the the DT cord-022526-j9kg00qf 1774 9 impairment impairment NN cord-022526-j9kg00qf 1774 10 of of IN cord-022526-j9kg00qf 1774 11 the the DT cord-022526-j9kg00qf 1774 12 systems system NNS cord-022526-j9kg00qf 1774 13 , , , cord-022526-j9kg00qf 1774 14 DIC DIC NNP cord-022526-j9kg00qf 1774 15 can can MD cord-022526-j9kg00qf 1774 16 manifest manifest VB cord-022526-j9kg00qf 1774 17 as as IN cord-022526-j9kg00qf 1774 18 a a DT cord-022526-j9kg00qf 1774 19 diffuse diffuse JJ cord-022526-j9kg00qf 1774 20 thrombotic thrombotic JJ cord-022526-j9kg00qf 1774 21 syndrome syndrome NN cord-022526-j9kg00qf 1774 22 leading lead VBG cord-022526-j9kg00qf 1774 23 to to IN cord-022526-j9kg00qf 1774 24 ischemic ischemic JJ cord-022526-j9kg00qf 1774 25 organ organ NN cord-022526-j9kg00qf 1774 26 failure failure NN cord-022526-j9kg00qf 1774 27 , , , cord-022526-j9kg00qf 1774 28 a a DT cord-022526-j9kg00qf 1774 29 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 1774 30 syndrome syndrome NN cord-022526-j9kg00qf 1774 31 with with IN cord-022526-j9kg00qf 1774 32 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 1774 33 hemorrhage hemorrhage NN cord-022526-j9kg00qf 1774 34 , , , cord-022526-j9kg00qf 1774 35 or or CC cord-022526-j9kg00qf 1774 36 a a DT cord-022526-j9kg00qf 1774 37 combination combination NN cord-022526-j9kg00qf 1774 38 of of IN cord-022526-j9kg00qf 1774 39 both both DT cord-022526-j9kg00qf 1774 40 . . . cord-022526-j9kg00qf 1775 1 74 74 CD cord-022526-j9kg00qf 1776 1 A a DT cord-022526-j9kg00qf 1776 2 procoagulant procoagulant JJ cord-022526-j9kg00qf 1776 3 state state NN cord-022526-j9kg00qf 1776 4 in in IN cord-022526-j9kg00qf 1776 5 which which WDT cord-022526-j9kg00qf 1776 6 one one PRP cord-022526-j9kg00qf 1776 7 can can MD cord-022526-j9kg00qf 1776 8 detect detect VB cord-022526-j9kg00qf 1776 9 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 1776 10 abnormalities abnormality NNS cord-022526-j9kg00qf 1776 11 precedes precede VBZ cord-022526-j9kg00qf 1776 12 DIC DIC NNP cord-022526-j9kg00qf 1776 13 . . . cord-022526-j9kg00qf 1777 1 Activation activation NN cord-022526-j9kg00qf 1777 2 of of IN cord-022526-j9kg00qf 1777 3 the the DT cord-022526-j9kg00qf 1777 4 coagulation coagulation NN cord-022526-j9kg00qf 1777 5 cascade cascade NN cord-022526-j9kg00qf 1777 6 culminates culminate VBZ cord-022526-j9kg00qf 1777 7 in in IN cord-022526-j9kg00qf 1777 8 the the DT cord-022526-j9kg00qf 1777 9 cleavage cleavage NN cord-022526-j9kg00qf 1777 10 of of IN cord-022526-j9kg00qf 1777 11 fibrinogen fibrinogen NN cord-022526-j9kg00qf 1777 12 to to IN cord-022526-j9kg00qf 1777 13 fibrin fibrin NN cord-022526-j9kg00qf 1777 14 by by IN cord-022526-j9kg00qf 1777 15 the the DT cord-022526-j9kg00qf 1777 16 serine serine NN cord-022526-j9kg00qf 1777 17 protease protease NN cord-022526-j9kg00qf 1778 1 thrombin thrombin JJ cord-022526-j9kg00qf 1778 2 . . . cord-022526-j9kg00qf 1779 1 Thrombin Thrombin NNP cord-022526-j9kg00qf 1779 2 deposition deposition NN cord-022526-j9kg00qf 1779 3 on on IN cord-022526-j9kg00qf 1779 4 endothelial endothelial JJ cord-022526-j9kg00qf 1779 5 cell cell NN cord-022526-j9kg00qf 1779 6 surfaces surface NNS cord-022526-j9kg00qf 1779 7 leads lead VBZ cord-022526-j9kg00qf 1779 8 to to IN cord-022526-j9kg00qf 1779 9 platelet platelet NN cord-022526-j9kg00qf 1779 10 adherence adherence NN cord-022526-j9kg00qf 1779 11 and and CC cord-022526-j9kg00qf 1779 12 their -PRON- PRP$ cord-022526-j9kg00qf 1779 13 activation activation NN cord-022526-j9kg00qf 1779 14 by by IN cord-022526-j9kg00qf 1779 15 surface surface NN cord-022526-j9kg00qf 1779 16 - - HYPH cord-022526-j9kg00qf 1779 17 bound bind VBN cord-022526-j9kg00qf 1779 18 PAF PAF NNP cord-022526-j9kg00qf 1779 19 . . . cord-022526-j9kg00qf 1780 1 56 56 CD cord-022526-j9kg00qf 1781 1 The the DT cord-022526-j9kg00qf 1781 2 intrinsic intrinsic JJ cord-022526-j9kg00qf 1781 3 and and CC cord-022526-j9kg00qf 1781 4 extrinsic extrinsic JJ cord-022526-j9kg00qf 1781 5 arms arm NNS cord-022526-j9kg00qf 1781 6 of of IN cord-022526-j9kg00qf 1781 7 the the DT cord-022526-j9kg00qf 1781 8 coagulation coagulation NN cord-022526-j9kg00qf 1781 9 cascade cascade NN cord-022526-j9kg00qf 1781 10 are be VBP cord-022526-j9kg00qf 1781 11 activated activate VBN cord-022526-j9kg00qf 1781 12 in in IN cord-022526-j9kg00qf 1781 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1781 14 . . . cord-022526-j9kg00qf 1782 1 The the DT cord-022526-j9kg00qf 1782 2 intrinsic intrinsic JJ cord-022526-j9kg00qf 1782 3 pathway pathway NN cord-022526-j9kg00qf 1782 4 is be VBZ cord-022526-j9kg00qf 1782 5 initiated initiate VBN cord-022526-j9kg00qf 1782 6 by by IN cord-022526-j9kg00qf 1782 7 activation activation NN cord-022526-j9kg00qf 1782 8 of of IN cord-022526-j9kg00qf 1782 9 coagulation coagulation NN cord-022526-j9kg00qf 1782 10 factor factor NN cord-022526-j9kg00qf 1782 11 XII XII NNP cord-022526-j9kg00qf 1782 12 ( ( -LRB- cord-022526-j9kg00qf 1782 13 Hageman Hageman NNP cord-022526-j9kg00qf 1782 14 factor factor NN cord-022526-j9kg00qf 1782 15 ) ) -RRB- cord-022526-j9kg00qf 1782 16 , , , cord-022526-j9kg00qf 1782 17 prekallikrein prekallikrein NNP cord-022526-j9kg00qf 1782 18 , , , cord-022526-j9kg00qf 1782 19 and and CC cord-022526-j9kg00qf 1782 20 highmolecular highmolecular NNP cord-022526-j9kg00qf 1782 21 - - HYPH cord-022526-j9kg00qf 1782 22 weight weight NN cord-022526-j9kg00qf 1782 23 kininogen kininogen NNP cord-022526-j9kg00qf 1782 24 , , , cord-022526-j9kg00qf 1782 25 which which WDT cord-022526-j9kg00qf 1782 26 compose compose VBP cord-022526-j9kg00qf 1782 27 the the DT cord-022526-j9kg00qf 1782 28 contact contact NN cord-022526-j9kg00qf 1782 29 system system NN cord-022526-j9kg00qf 1782 30 . . . cord-022526-j9kg00qf 1783 1 75 75 CD cord-022526-j9kg00qf 1784 1 Although although IN cord-022526-j9kg00qf 1784 2 direct direct JJ cord-022526-j9kg00qf 1784 3 activation activation NN cord-022526-j9kg00qf 1784 4 of of IN cord-022526-j9kg00qf 1784 5 coagulation coagulation NN cord-022526-j9kg00qf 1784 6 factor factor NN cord-022526-j9kg00qf 1784 7 XII XII NNP cord-022526-j9kg00qf 1784 8 by by IN cord-022526-j9kg00qf 1784 9 endotoxin endotoxin NN cord-022526-j9kg00qf 1784 10 has have VBZ cord-022526-j9kg00qf 1784 11 been be VBN cord-022526-j9kg00qf 1784 12 demonstrated demonstrate VBN cord-022526-j9kg00qf 1784 13 , , , cord-022526-j9kg00qf 1784 14 76 76 CD cord-022526-j9kg00qf 1784 15 the the DT cord-022526-j9kg00qf 1784 16 extrinsic extrinsic JJ cord-022526-j9kg00qf 1784 17 pathway pathway NN cord-022526-j9kg00qf 1784 18 likely likely RB cord-022526-j9kg00qf 1784 19 is be VBZ cord-022526-j9kg00qf 1784 20 more more RBR cord-022526-j9kg00qf 1784 21 important important JJ cord-022526-j9kg00qf 1784 22 for for IN cord-022526-j9kg00qf 1784 23 the the DT cord-022526-j9kg00qf 1784 24 development development NN cord-022526-j9kg00qf 1784 25 of of IN cord-022526-j9kg00qf 1784 26 coagulopathy coagulopathy NN cord-022526-j9kg00qf 1784 27 in in IN cord-022526-j9kg00qf 1784 28 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1784 29 and and CC cord-022526-j9kg00qf 1784 30 sepsis sepsis NN cord-022526-j9kg00qf 1784 31 . . . cord-022526-j9kg00qf 1785 1 75 75 CD cord-022526-j9kg00qf 1785 2 Activation activation NN cord-022526-j9kg00qf 1785 3 of of IN cord-022526-j9kg00qf 1785 4 the the DT cord-022526-j9kg00qf 1785 5 extrinsic extrinsic JJ cord-022526-j9kg00qf 1785 6 pathway pathway NN cord-022526-j9kg00qf 1785 7 depends depend VBZ cord-022526-j9kg00qf 1785 8 on on IN cord-022526-j9kg00qf 1785 9 the the DT cord-022526-j9kg00qf 1785 10 interaction interaction NN cord-022526-j9kg00qf 1785 11 of of IN cord-022526-j9kg00qf 1785 12 coagulation coagulation NN cord-022526-j9kg00qf 1785 13 factor factor NN cord-022526-j9kg00qf 1785 14 VII vii NN cord-022526-j9kg00qf 1785 15 with with IN cord-022526-j9kg00qf 1785 16 tissue tissue NN cord-022526-j9kg00qf 1785 17 factor factor NN cord-022526-j9kg00qf 1785 18 , , , cord-022526-j9kg00qf 1785 19 which which WDT cord-022526-j9kg00qf 1785 20 is be VBZ cord-022526-j9kg00qf 1785 21 the the DT cord-022526-j9kg00qf 1785 22 only only JJ cord-022526-j9kg00qf 1785 23 coagulation coagulation NN cord-022526-j9kg00qf 1785 24 factor factor NN cord-022526-j9kg00qf 1785 25 not not RB cord-022526-j9kg00qf 1785 26 constitutively constitutively RB cord-022526-j9kg00qf 1785 27 present present JJ cord-022526-j9kg00qf 1785 28 in in IN cord-022526-j9kg00qf 1785 29 blood blood NN cord-022526-j9kg00qf 1785 30 . . . cord-022526-j9kg00qf 1786 1 Tissue tissue NN cord-022526-j9kg00qf 1786 2 factor factor NN cord-022526-j9kg00qf 1786 3 is be VBZ cord-022526-j9kg00qf 1786 4 present present JJ cord-022526-j9kg00qf 1786 5 in in IN cord-022526-j9kg00qf 1786 6 subendothelial subendothelial JJ cord-022526-j9kg00qf 1786 7 tissues tissue NNS cord-022526-j9kg00qf 1786 8 and and CC cord-022526-j9kg00qf 1786 9 is be VBZ cord-022526-j9kg00qf 1786 10 exposed expose VBN cord-022526-j9kg00qf 1786 11 on on IN cord-022526-j9kg00qf 1786 12 vascular vascular JJ cord-022526-j9kg00qf 1786 13 injury injury NN cord-022526-j9kg00qf 1786 14 but but CC cord-022526-j9kg00qf 1786 15 also also RB cord-022526-j9kg00qf 1786 16 is be VBZ cord-022526-j9kg00qf 1786 17 expressed express VBN cord-022526-j9kg00qf 1786 18 on on IN cord-022526-j9kg00qf 1786 19 endothelial endothelial JJ cord-022526-j9kg00qf 1786 20 cells cell NNS cord-022526-j9kg00qf 1786 21 and and CC cord-022526-j9kg00qf 1786 22 mononuclear mononuclear JJ cord-022526-j9kg00qf 1786 23 phagocytes phagocyte NNS cord-022526-j9kg00qf 1786 24 in in IN cord-022526-j9kg00qf 1786 25 response response NN cord-022526-j9kg00qf 1786 26 to to IN cord-022526-j9kg00qf 1786 27 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1786 28 . . . cord-022526-j9kg00qf 1787 1 77 77 CD cord-022526-j9kg00qf 1787 2 , , , cord-022526-j9kg00qf 1787 3 78 78 CD cord-022526-j9kg00qf 1787 4 Increased increase VBN cord-022526-j9kg00qf 1787 5 expression expression NN cord-022526-j9kg00qf 1787 6 of of IN cord-022526-j9kg00qf 1787 7 monocyte monocyte JJ cord-022526-j9kg00qf 1787 8 tissue tissue NN cord-022526-j9kg00qf 1787 9 factor factor NN cord-022526-j9kg00qf 1787 10 ( ( -LRB- cord-022526-j9kg00qf 1787 11 also also RB cord-022526-j9kg00qf 1787 12 described describe VBN cord-022526-j9kg00qf 1787 13 as as IN cord-022526-j9kg00qf 1787 14 increased increase VBN cord-022526-j9kg00qf 1787 15 procoagulant procoagulant NN cord-022526-j9kg00qf 1787 16 activity activity NN cord-022526-j9kg00qf 1787 17 ) ) -RRB- cord-022526-j9kg00qf 1787 18 was be VBD cord-022526-j9kg00qf 1787 19 found find VBN cord-022526-j9kg00qf 1787 20 to to TO cord-022526-j9kg00qf 1787 21 be be VB cord-022526-j9kg00qf 1787 22 associated associate VBN cord-022526-j9kg00qf 1787 23 significantly significantly RB cord-022526-j9kg00qf 1787 24 with with IN cord-022526-j9kg00qf 1787 25 coagulopathy coagulopathy NN cord-022526-j9kg00qf 1787 26 and and CC cord-022526-j9kg00qf 1787 27 poor poor JJ cord-022526-j9kg00qf 1787 28 prognosis prognosis NN cord-022526-j9kg00qf 1787 29 in in IN cord-022526-j9kg00qf 1787 30 horses horse NNS cord-022526-j9kg00qf 1787 31 with with IN cord-022526-j9kg00qf 1787 32 colic colic NN cord-022526-j9kg00qf 1787 33 . . . cord-022526-j9kg00qf 1788 1 79 79 CD cord-022526-j9kg00qf 1789 1 Furthermore furthermore RB cord-022526-j9kg00qf 1789 2 , , , cord-022526-j9kg00qf 1789 3 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1789 4 - - HYPH cord-022526-j9kg00qf 1789 5 induced induce VBN cord-022526-j9kg00qf 1789 6 tissue tissue NN cord-022526-j9kg00qf 1789 7 factor factor NN cord-022526-j9kg00qf 1789 8 expression expression NN cord-022526-j9kg00qf 1789 9 by by IN cord-022526-j9kg00qf 1789 10 equine equine JJ cord-022526-j9kg00qf 1789 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 1789 12 macrophages macrophage NNS cord-022526-j9kg00qf 1789 13 may may MD cord-022526-j9kg00qf 1789 14 be be VB cord-022526-j9kg00qf 1789 15 associated associate VBN cord-022526-j9kg00qf 1789 16 with with IN cord-022526-j9kg00qf 1789 17 the the DT cord-022526-j9kg00qf 1789 18 development development NN cord-022526-j9kg00qf 1789 19 of of IN cord-022526-j9kg00qf 1789 20 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 1789 21 adhesions adhesion NNS cord-022526-j9kg00qf 1789 22 . . . cord-022526-j9kg00qf 1790 1 63 63 CD cord-022526-j9kg00qf 1790 2 Regulatory regulatory JJ cord-022526-j9kg00qf 1790 3 mechanisms mechanism NNS cord-022526-j9kg00qf 1790 4 of of IN cord-022526-j9kg00qf 1790 5 the the DT cord-022526-j9kg00qf 1790 6 coagulation coagulation NN cord-022526-j9kg00qf 1790 7 cascade cascade NN cord-022526-j9kg00qf 1790 8 include include VBP cord-022526-j9kg00qf 1790 9 tissue tissue NN cord-022526-j9kg00qf 1790 10 factor factor NN cord-022526-j9kg00qf 1790 11 pathway pathway NN cord-022526-j9kg00qf 1790 12 inhibitor inhibitor NN cord-022526-j9kg00qf 1790 13 , , , cord-022526-j9kg00qf 1790 14 antithrombin antithrombin NN cord-022526-j9kg00qf 1790 15 III III NNP cord-022526-j9kg00qf 1790 16 ( ( -LRB- cord-022526-j9kg00qf 1790 17 AT at IN cord-022526-j9kg00qf 1790 18 III III NNP cord-022526-j9kg00qf 1790 19 ) ) -RRB- cord-022526-j9kg00qf 1790 20 , , , cord-022526-j9kg00qf 1790 21 and and CC cord-022526-j9kg00qf 1790 22 the the DT cord-022526-j9kg00qf 1790 23 protein protein NN cord-022526-j9kg00qf 1790 24 C c NN cord-022526-j9kg00qf 1790 25 system system NN cord-022526-j9kg00qf 1790 26 . . . cord-022526-j9kg00qf 1791 1 75 75 CD cord-022526-j9kg00qf 1791 2 Protein protein NN cord-022526-j9kg00qf 1791 3 C C NNP cord-022526-j9kg00qf 1791 4 acts act VBZ cord-022526-j9kg00qf 1791 5 as as IN cord-022526-j9kg00qf 1791 6 an an DT cord-022526-j9kg00qf 1791 7 anticoagulant anticoagulant NN cord-022526-j9kg00qf 1791 8 by by IN cord-022526-j9kg00qf 1791 9 inactivating inactivate VBG cord-022526-j9kg00qf 1791 10 clotting clotting NN cord-022526-j9kg00qf 1791 11 factors factor NNS cord-022526-j9kg00qf 1791 12 V v NN cord-022526-j9kg00qf 1791 13 and and CC cord-022526-j9kg00qf 1791 14 VIII VIII NNP cord-022526-j9kg00qf 1791 15 and and CC cord-022526-j9kg00qf 1791 16 promotes promote VBZ cord-022526-j9kg00qf 1791 17 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 1791 18 by by IN cord-022526-j9kg00qf 1791 19 inactivating inactivate VBG cord-022526-j9kg00qf 1791 20 plasminogen plasminogen NN cord-022526-j9kg00qf 1791 21 activator activator NN cord-022526-j9kg00qf 1791 22 inhibitor inhibitor NN cord-022526-j9kg00qf 1791 23 ( ( -LRB- cord-022526-j9kg00qf 1791 24 PAI PAI NNP cord-022526-j9kg00qf 1791 25 ) ) -RRB- cord-022526-j9kg00qf 1791 26 . . . cord-022526-j9kg00qf 1792 1 80 80 CD cord-022526-j9kg00qf 1792 2 Protein Protein NNP cord-022526-j9kg00qf 1792 3 C C NNP cord-022526-j9kg00qf 1792 4 activation activation NN cord-022526-j9kg00qf 1792 5 by by IN cord-022526-j9kg00qf 1792 6 thrombin thrombin NN cord-022526-j9kg00qf 1792 7 - - HYPH cord-022526-j9kg00qf 1792 8 thrombomodulin thrombomodulin NN cord-022526-j9kg00qf 1792 9 complexes complex NNS cord-022526-j9kg00qf 1792 10 is be VBZ cord-022526-j9kg00qf 1792 11 important important JJ cord-022526-j9kg00qf 1792 12 for for IN cord-022526-j9kg00qf 1792 13 the the DT cord-022526-j9kg00qf 1792 14 anticoagulative anticoagulative JJ cord-022526-j9kg00qf 1792 15 properties property NNS cord-022526-j9kg00qf 1792 16 of of IN cord-022526-j9kg00qf 1792 17 normal normal JJ cord-022526-j9kg00qf 1792 18 endothelium endothelium NN cord-022526-j9kg00qf 1792 19 , , , cord-022526-j9kg00qf 1792 20 75 75 CD cord-022526-j9kg00qf 1792 21 and and CC cord-022526-j9kg00qf 1792 22 downregulation downregulation NN cord-022526-j9kg00qf 1792 23 of of IN cord-022526-j9kg00qf 1792 24 endothelial endothelial JJ cord-022526-j9kg00qf 1792 25 thrombomodulin thrombomodulin NN cord-022526-j9kg00qf 1792 26 expression expression NN cord-022526-j9kg00qf 1792 27 by by IN cord-022526-j9kg00qf 1792 28 TNF TNF NNP cord-022526-j9kg00qf 1792 29 and and CC cord-022526-j9kg00qf 1792 30 IL-1 IL-1 NNP cord-022526-j9kg00qf 1792 31 and and CC cord-022526-j9kg00qf 1792 32 decreased decrease VBD cord-022526-j9kg00qf 1792 33 expression expression NN cord-022526-j9kg00qf 1792 34 of of IN cord-022526-j9kg00qf 1792 35 AT AT NNP cord-022526-j9kg00qf 1792 36 III iii CD cord-022526-j9kg00qf 1792 37 and and CC cord-022526-j9kg00qf 1792 38 tissue tissue NN cord-022526-j9kg00qf 1792 39 factor factor NN cord-022526-j9kg00qf 1792 40 pathway pathway NN cord-022526-j9kg00qf 1792 41 inhibitor inhibitor NN cord-022526-j9kg00qf 1792 42 by by IN cord-022526-j9kg00qf 1792 43 damaged damaged JJ cord-022526-j9kg00qf 1792 44 endothelial endothelial JJ cord-022526-j9kg00qf 1792 45 cells cell NNS cord-022526-j9kg00qf 1792 46 contribute contribute VBP cord-022526-j9kg00qf 1792 47 to to IN cord-022526-j9kg00qf 1792 48 the the DT cord-022526-j9kg00qf 1792 49 procoagulant procoagulant JJ cord-022526-j9kg00qf 1792 50 state state NN cord-022526-j9kg00qf 1792 51 in in IN cord-022526-j9kg00qf 1792 52 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1792 53 and and CC cord-022526-j9kg00qf 1792 54 sepsis sepsis NN cord-022526-j9kg00qf 1792 55 . . . cord-022526-j9kg00qf 1793 1 [ [ -LRB- cord-022526-j9kg00qf 1793 2 81 81 CD cord-022526-j9kg00qf 1793 3 ] ] -RRB- cord-022526-j9kg00qf 1793 4 [ [ -LRB- cord-022526-j9kg00qf 1793 5 82 82 CD cord-022526-j9kg00qf 1793 6 ] ] -RRB- cord-022526-j9kg00qf 1794 1 [ [ -LRB- cord-022526-j9kg00qf 1794 2 83 83 CD cord-022526-j9kg00qf 1794 3 ] ] -RRB- cord-022526-j9kg00qf 1795 1 In in IN cord-022526-j9kg00qf 1795 2 addition addition NN cord-022526-j9kg00qf 1795 3 , , , cord-022526-j9kg00qf 1795 4 activation activation NN cord-022526-j9kg00qf 1795 5 of of IN cord-022526-j9kg00qf 1795 6 vascular vascular JJ cord-022526-j9kg00qf 1795 7 endothelial endothelial JJ cord-022526-j9kg00qf 1795 8 cells cell NNS cord-022526-j9kg00qf 1795 9 leads lead VBZ cord-022526-j9kg00qf 1795 10 to to IN cord-022526-j9kg00qf 1795 11 a a DT cord-022526-j9kg00qf 1795 12 loss loss NN cord-022526-j9kg00qf 1795 13 of of IN cord-022526-j9kg00qf 1795 14 prostacyclin prostacyclin NN cord-022526-j9kg00qf 1795 15 and and CC cord-022526-j9kg00qf 1795 16 NO no DT cord-022526-j9kg00qf 1795 17 production production NN cord-022526-j9kg00qf 1795 18 and and CC cord-022526-j9kg00qf 1795 19 an an DT cord-022526-j9kg00qf 1795 20 increased increase VBN cord-022526-j9kg00qf 1795 21 release release NN cord-022526-j9kg00qf 1795 22 of of IN cord-022526-j9kg00qf 1795 23 thromboxane thromboxane NN cord-022526-j9kg00qf 1795 24 A A NNP cord-022526-j9kg00qf 1795 25 2 2 CD cord-022526-j9kg00qf 1795 26 ( ( -LRB- cord-022526-j9kg00qf 1795 27 TXA TXA NNP cord-022526-j9kg00qf 1795 28 2 2 CD cord-022526-j9kg00qf 1795 29 ) ) -RRB- cord-022526-j9kg00qf 1795 30 . . . cord-022526-j9kg00qf 1796 1 As as IN cord-022526-j9kg00qf 1796 2 a a DT cord-022526-j9kg00qf 1796 3 result result NN cord-022526-j9kg00qf 1796 4 , , , cord-022526-j9kg00qf 1796 5 platelets platelet NNS cord-022526-j9kg00qf 1796 6 are be VBP cord-022526-j9kg00qf 1796 7 stimulated stimulate VBN cord-022526-j9kg00qf 1796 8 to to IN cord-022526-j9kg00qf 1796 9 aggregate aggregate NN cord-022526-j9kg00qf 1796 10 and and CC cord-022526-j9kg00qf 1796 11 release release VB cord-022526-j9kg00qf 1796 12 TXA TXA NNP cord-022526-j9kg00qf 1796 13 2 2 CD cord-022526-j9kg00qf 1796 14 and and CC cord-022526-j9kg00qf 1796 15 PAF PAF NNP cord-022526-j9kg00qf 1796 16 , , , cord-022526-j9kg00qf 1796 17 thereby thereby RB cord-022526-j9kg00qf 1796 18 further further RB cord-022526-j9kg00qf 1796 19 promoting promote VBG cord-022526-j9kg00qf 1796 20 clot clot NN cord-022526-j9kg00qf 1796 21 formation formation NN cord-022526-j9kg00qf 1796 22 . . . cord-022526-j9kg00qf 1797 1 17 17 CD cord-022526-j9kg00qf 1798 1 The the DT cord-022526-j9kg00qf 1798 2 crucial crucial JJ cord-022526-j9kg00qf 1798 3 step step NN cord-022526-j9kg00qf 1798 4 in in IN cord-022526-j9kg00qf 1798 5 the the DT cord-022526-j9kg00qf 1798 6 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 1798 7 cascade cascade NN cord-022526-j9kg00qf 1798 8 is be VBZ cord-022526-j9kg00qf 1798 9 the the DT cord-022526-j9kg00qf 1798 10 conversion conversion NN cord-022526-j9kg00qf 1798 11 of of IN cord-022526-j9kg00qf 1798 12 plasminogen plasminogen NN cord-022526-j9kg00qf 1798 13 to to IN cord-022526-j9kg00qf 1798 14 plasmin plasmin NNP cord-022526-j9kg00qf 1798 15 , , , cord-022526-j9kg00qf 1798 16 a a DT cord-022526-j9kg00qf 1798 17 fibrin fibrin NN cord-022526-j9kg00qf 1798 18 - - HYPH cord-022526-j9kg00qf 1798 19 degrading degrade VBG cord-022526-j9kg00qf 1798 20 enzyme enzyme NN cord-022526-j9kg00qf 1798 21 . . . cord-022526-j9kg00qf 1799 1 75 75 CD cord-022526-j9kg00qf 1799 2 Tissue tissue NN cord-022526-j9kg00qf 1799 3 - - HYPH cord-022526-j9kg00qf 1799 4 type type NN cord-022526-j9kg00qf 1799 5 ( ( -LRB- cord-022526-j9kg00qf 1799 6 tPA tPA NNP cord-022526-j9kg00qf 1799 7 ) ) -RRB- cord-022526-j9kg00qf 1799 8 and and CC cord-022526-j9kg00qf 1799 9 urokinase urokinase NN cord-022526-j9kg00qf 1799 10 - - HYPH cord-022526-j9kg00qf 1799 11 type type NN cord-022526-j9kg00qf 1799 12 ( ( -LRB- cord-022526-j9kg00qf 1799 13 uPA upa NN cord-022526-j9kg00qf 1799 14 ) ) -RRB- cord-022526-j9kg00qf 1799 15 plasminogen plasminogen NN cord-022526-j9kg00qf 1799 16 activator activator NN cord-022526-j9kg00qf 1799 17 are be VBP cord-022526-j9kg00qf 1799 18 the the DT cord-022526-j9kg00qf 1799 19 major major JJ cord-022526-j9kg00qf 1799 20 initiators initiator NNS cord-022526-j9kg00qf 1799 21 of of IN cord-022526-j9kg00qf 1799 22 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 1799 23 , , , cord-022526-j9kg00qf 1799 24 whereas whereas IN cord-022526-j9kg00qf 1799 25 PAI PAI NNP cord-022526-j9kg00qf 1799 26 and and CC cord-022526-j9kg00qf 1799 27 α α NN cord-022526-j9kg00qf 1799 28 2 2 CD cord-022526-j9kg00qf 1799 29 -antiplasmin -antiplasmin NNP cord-022526-j9kg00qf 1799 30 are be VBP cord-022526-j9kg00qf 1799 31 the the DT cord-022526-j9kg00qf 1799 32 main main JJ cord-022526-j9kg00qf 1799 33 regulatory regulatory JJ cord-022526-j9kg00qf 1799 34 components component NNS cord-022526-j9kg00qf 1799 35 . . . cord-022526-j9kg00qf 1800 1 84 84 CD cord-022526-j9kg00qf 1800 2 , , , cord-022526-j9kg00qf 1800 3 85 85 CD cord-022526-j9kg00qf 1800 4 TNF TNF NNP cord-022526-j9kg00qf 1800 5 and and CC cord-022526-j9kg00qf 1800 6 IL-1 IL-1 NNP cord-022526-j9kg00qf 1800 7 have have VBP cord-022526-j9kg00qf 1800 8 been be VBN cord-022526-j9kg00qf 1800 9 shown show VBN cord-022526-j9kg00qf 1800 10 to to TO cord-022526-j9kg00qf 1800 11 induce induce VB cord-022526-j9kg00qf 1800 12 the the DT cord-022526-j9kg00qf 1800 13 release release NN cord-022526-j9kg00qf 1800 14 of of IN cord-022526-j9kg00qf 1800 15 uPA uPA NNP cord-022526-j9kg00qf 1800 16 and and CC cord-022526-j9kg00qf 1800 17 tPA tPA NNP cord-022526-j9kg00qf 1800 18 and and CC cord-022526-j9kg00qf 1800 19 the the DT cord-022526-j9kg00qf 1800 20 synthesis synthesis NN cord-022526-j9kg00qf 1800 21 of of IN cord-022526-j9kg00qf 1800 22 PAI PAI NNP cord-022526-j9kg00qf 1800 23 . . . cord-022526-j9kg00qf 1801 1 75 75 CD cord-022526-j9kg00qf 1801 2 Activation activation NN cord-022526-j9kg00qf 1801 3 of of IN cord-022526-j9kg00qf 1801 4 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 1801 5 leads lead VBZ cord-022526-j9kg00qf 1801 6 to to IN cord-022526-j9kg00qf 1801 7 consumption consumption NN cord-022526-j9kg00qf 1801 8 of of IN cord-022526-j9kg00qf 1801 9 α α NN cord-022526-j9kg00qf 1801 10 2 2 CD cord-022526-j9kg00qf 1801 11 -antiplasmin -antiplasmin SYM cord-022526-j9kg00qf 1801 12 and and CC cord-022526-j9kg00qf 1801 13 accumulation accumulation NN cord-022526-j9kg00qf 1801 14 of of IN cord-022526-j9kg00qf 1801 15 FDPs fdp NNS cord-022526-j9kg00qf 1801 16 , , , cord-022526-j9kg00qf 1801 17 which which WDT cord-022526-j9kg00qf 1801 18 if if IN cord-022526-j9kg00qf 1801 19 present present JJ cord-022526-j9kg00qf 1801 20 in in IN cord-022526-j9kg00qf 1801 21 high high JJ cord-022526-j9kg00qf 1801 22 concentrations concentration NNS cord-022526-j9kg00qf 1801 23 can can MD cord-022526-j9kg00qf 1801 24 interfere interfere VB cord-022526-j9kg00qf 1801 25 with with IN cord-022526-j9kg00qf 1801 26 platelet platelet NN cord-022526-j9kg00qf 1801 27 aggregation aggregation NN cord-022526-j9kg00qf 1801 28 , , , cord-022526-j9kg00qf 1801 29 fibrin fibrin NN cord-022526-j9kg00qf 1801 30 polymerization polymerization NN cord-022526-j9kg00qf 1801 31 , , , cord-022526-j9kg00qf 1801 32 and and CC cord-022526-j9kg00qf 1801 33 thrombin thrombin JJ cord-022526-j9kg00qf 1801 34 formation formation NN cord-022526-j9kg00qf 1801 35 and and CC cord-022526-j9kg00qf 1801 36 can can MD cord-022526-j9kg00qf 1801 37 promote promote VB cord-022526-j9kg00qf 1801 38 bleeding bleed VBG cord-022526-j9kg00qf 1801 39 . . . cord-022526-j9kg00qf 1802 1 Additionally additionally RB cord-022526-j9kg00qf 1802 2 , , , cord-022526-j9kg00qf 1802 3 FDPs fdp NNS cord-022526-j9kg00qf 1802 4 mediate mediate VBP cord-022526-j9kg00qf 1802 5 an an DT cord-022526-j9kg00qf 1802 6 increase increase NN cord-022526-j9kg00qf 1802 7 in in IN cord-022526-j9kg00qf 1802 8 vascular vascular JJ cord-022526-j9kg00qf 1802 9 permeability permeability NN cord-022526-j9kg00qf 1802 10 . . . cord-022526-j9kg00qf 1803 1 Lipopolysaccharide Lipopolysaccharide NNP cord-022526-j9kg00qf 1803 2 infusion infusion NN cord-022526-j9kg00qf 1803 3 in in IN cord-022526-j9kg00qf 1803 4 rabbits rabbit NNS cord-022526-j9kg00qf 1803 5 86 86 CD cord-022526-j9kg00qf 1803 6 and and CC cord-022526-j9kg00qf 1803 7 human human JJ cord-022526-j9kg00qf 1803 8 beings being NNS cord-022526-j9kg00qf 1803 9 87 87 CD cord-022526-j9kg00qf 1803 10 resulted result VBD cord-022526-j9kg00qf 1803 11 in in IN cord-022526-j9kg00qf 1803 12 an an DT cord-022526-j9kg00qf 1803 13 early early JJ cord-022526-j9kg00qf 1803 14 increase increase NN cord-022526-j9kg00qf 1803 15 in in IN cord-022526-j9kg00qf 1803 16 plasma plasma NN cord-022526-j9kg00qf 1803 17 tPA tpa NN cord-022526-j9kg00qf 1803 18 activity activity NN cord-022526-j9kg00qf 1803 19 , , , cord-022526-j9kg00qf 1803 20 followed follow VBN cord-022526-j9kg00qf 1803 21 by by IN cord-022526-j9kg00qf 1803 22 a a DT cord-022526-j9kg00qf 1803 23 later later JJ cord-022526-j9kg00qf 1803 24 profound profound JJ cord-022526-j9kg00qf 1803 25 rise rise NN cord-022526-j9kg00qf 1803 26 in in IN cord-022526-j9kg00qf 1803 27 PAI PAI NNP cord-022526-j9kg00qf 1803 28 activity activity NN cord-022526-j9kg00qf 1803 29 and and CC cord-022526-j9kg00qf 1803 30 fall fall NN cord-022526-j9kg00qf 1803 31 in in IN cord-022526-j9kg00qf 1803 32 tPA tPA NNP cord-022526-j9kg00qf 1803 33 activity activity NN cord-022526-j9kg00qf 1803 34 . . . cord-022526-j9kg00qf 1804 1 Increased increase VBN cord-022526-j9kg00qf 1804 2 plasma plasma NN cord-022526-j9kg00qf 1804 3 PAI PAI NNP cord-022526-j9kg00qf 1804 4 concentrations concentration NNS cord-022526-j9kg00qf 1804 5 also also RB cord-022526-j9kg00qf 1804 6 were be VBD cord-022526-j9kg00qf 1804 7 found find VBN cord-022526-j9kg00qf 1804 8 in in IN cord-022526-j9kg00qf 1804 9 horses horse NNS cord-022526-j9kg00qf 1804 10 with with IN cord-022526-j9kg00qf 1804 11 colic colic NN cord-022526-j9kg00qf 1804 12 compared compare VBN cord-022526-j9kg00qf 1804 13 with with IN cord-022526-j9kg00qf 1804 14 controls control NNS cord-022526-j9kg00qf 1804 15 . . . cord-022526-j9kg00qf 1805 1 88 88 CD cord-022526-j9kg00qf 1805 2 , , , cord-022526-j9kg00qf 1805 3 89 89 CD cord-022526-j9kg00qf 1806 1 Thus thus RB cord-022526-j9kg00qf 1806 2 although although IN cord-022526-j9kg00qf 1806 3 fibrinolysis fibrinolysis NNP cord-022526-j9kg00qf 1806 4 may may MD cord-022526-j9kg00qf 1806 5 compensate compensate VB cord-022526-j9kg00qf 1806 6 initially initially RB cord-022526-j9kg00qf 1806 7 for for IN cord-022526-j9kg00qf 1806 8 accelerated accelerated JJ cord-022526-j9kg00qf 1806 9 coagulation coagulation NN cord-022526-j9kg00qf 1806 10 , , , cord-022526-j9kg00qf 1806 11 its -PRON- PRP$ cord-022526-j9kg00qf 1806 12 subsequent subsequent JJ cord-022526-j9kg00qf 1806 13 inhibition inhibition NN cord-022526-j9kg00qf 1806 14 contributes contribute VBZ cord-022526-j9kg00qf 1806 15 to to IN cord-022526-j9kg00qf 1806 16 clot clot NN cord-022526-j9kg00qf 1806 17 formation formation NN cord-022526-j9kg00qf 1806 18 . . . cord-022526-j9kg00qf 1807 1 Activation activation NN cord-022526-j9kg00qf 1807 2 of of IN cord-022526-j9kg00qf 1807 3 the the DT cord-022526-j9kg00qf 1807 4 complement complement JJ cord-022526-j9kg00qf 1807 5 system system NN cord-022526-j9kg00qf 1807 6 in in IN cord-022526-j9kg00qf 1807 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1807 8 occurs occur VBZ cord-022526-j9kg00qf 1807 9 via via IN cord-022526-j9kg00qf 1807 10 the the DT cord-022526-j9kg00qf 1807 11 alternative alternative JJ cord-022526-j9kg00qf 1807 12 pathway pathway NN cord-022526-j9kg00qf 1807 13 through through IN cord-022526-j9kg00qf 1807 14 interaction interaction NN cord-022526-j9kg00qf 1807 15 with with IN cord-022526-j9kg00qf 1807 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1807 17 . . . cord-022526-j9kg00qf 1808 1 Increased increase VBN cord-022526-j9kg00qf 1808 2 concentrations concentration NNS cord-022526-j9kg00qf 1808 3 of of IN cord-022526-j9kg00qf 1808 4 plasmin plasmin NNP cord-022526-j9kg00qf 1808 5 and and CC cord-022526-j9kg00qf 1808 6 kallikrein kallikrein NNP cord-022526-j9kg00qf 1808 7 ( ( -LRB- cord-022526-j9kg00qf 1808 8 caused cause VBN cord-022526-j9kg00qf 1808 9 by by IN cord-022526-j9kg00qf 1808 10 activation activation NN cord-022526-j9kg00qf 1808 11 of of IN cord-022526-j9kg00qf 1808 12 the the DT cord-022526-j9kg00qf 1808 13 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 1808 14 and and CC cord-022526-j9kg00qf 1808 15 contact contact NN cord-022526-j9kg00qf 1808 16 system system NN cord-022526-j9kg00qf 1808 17 ) ) -RRB- cord-022526-j9kg00qf 1808 18 further further RB cord-022526-j9kg00qf 1808 19 promote promote VB cord-022526-j9kg00qf 1808 20 this this DT cord-022526-j9kg00qf 1808 21 pathway pathway NN cord-022526-j9kg00qf 1808 22 by by IN cord-022526-j9kg00qf 1808 23 directly directly RB cord-022526-j9kg00qf 1808 24 activating activate VBG cord-022526-j9kg00qf 1808 25 complement complement NN cord-022526-j9kg00qf 1808 26 factors factor NNS cord-022526-j9kg00qf 1808 27 C3a C3a NNS cord-022526-j9kg00qf 1808 28 and and CC cord-022526-j9kg00qf 1808 29 C5a C5a NNS cord-022526-j9kg00qf 1808 30 . . . cord-022526-j9kg00qf 1809 1 Aside aside RB cord-022526-j9kg00qf 1809 2 from from IN cord-022526-j9kg00qf 1809 3 being be VBG cord-022526-j9kg00qf 1809 4 key key JJ cord-022526-j9kg00qf 1809 5 molecules molecule NNS cord-022526-j9kg00qf 1809 6 in in IN cord-022526-j9kg00qf 1809 7 the the DT cord-022526-j9kg00qf 1809 8 complement complement NN cord-022526-j9kg00qf 1809 9 cascade cascade NN cord-022526-j9kg00qf 1809 10 , , , cord-022526-j9kg00qf 1809 11 C3a C3a NNP cord-022526-j9kg00qf 1809 12 and and CC cord-022526-j9kg00qf 1809 13 C5a C5a NNS cord-022526-j9kg00qf 1809 14 are be VBP cord-022526-j9kg00qf 1809 15 anaphylatoxins anaphylatoxin NNS cord-022526-j9kg00qf 1809 16 and and CC cord-022526-j9kg00qf 1809 17 cause cause VB cord-022526-j9kg00qf 1809 18 an an DT cord-022526-j9kg00qf 1809 19 increase increase NN cord-022526-j9kg00qf 1809 20 in in IN cord-022526-j9kg00qf 1809 21 vascular vascular JJ cord-022526-j9kg00qf 1809 22 permeability permeability NN cord-022526-j9kg00qf 1809 23 via via IN cord-022526-j9kg00qf 1809 24 mast mast JJ cord-022526-j9kg00qf 1809 25 cell cell NN cord-022526-j9kg00qf 1809 26 degranulation degranulation NN cord-022526-j9kg00qf 1809 27 . . . cord-022526-j9kg00qf 1810 1 C5a C5a NNS cord-022526-j9kg00qf 1810 2 further further RB cord-022526-j9kg00qf 1810 3 activates activate VBZ cord-022526-j9kg00qf 1810 4 the the DT cord-022526-j9kg00qf 1810 5 lipoxygenase lipoxygenase NN cord-022526-j9kg00qf 1810 6 pathway pathway NN cord-022526-j9kg00qf 1810 7 in in IN cord-022526-j9kg00qf 1810 8 neutrophils neutrophil NNS cord-022526-j9kg00qf 1810 9 and and CC cord-022526-j9kg00qf 1810 10 monocytes monocyte NNS cord-022526-j9kg00qf 1810 11 , , , cord-022526-j9kg00qf 1810 12 acts act VBZ cord-022526-j9kg00qf 1810 13 as as IN cord-022526-j9kg00qf 1810 14 a a DT cord-022526-j9kg00qf 1810 15 chemotaxin chemotaxin NN cord-022526-j9kg00qf 1810 16 for for IN cord-022526-j9kg00qf 1810 17 leukocytes leukocyte NNS cord-022526-j9kg00qf 1810 18 and and CC cord-022526-j9kg00qf 1810 19 monocytes monocyte NNS cord-022526-j9kg00qf 1810 20 , , , cord-022526-j9kg00qf 1810 21 and and CC cord-022526-j9kg00qf 1810 22 promotes promote VBZ cord-022526-j9kg00qf 1810 23 neutrophil neutrophil NN cord-022526-j9kg00qf 1810 24 adhesion adhesion NN cord-022526-j9kg00qf 1810 25 to to IN cord-022526-j9kg00qf 1810 26 endothelial endothelial JJ cord-022526-j9kg00qf 1810 27 cells cell NNS cord-022526-j9kg00qf 1810 28 . . . cord-022526-j9kg00qf 1811 1 In in IN cord-022526-j9kg00qf 1811 2 response response NN cord-022526-j9kg00qf 1811 3 to to IN cord-022526-j9kg00qf 1811 4 acute acute JJ cord-022526-j9kg00qf 1811 5 inflammation inflammation NN cord-022526-j9kg00qf 1811 6 , , , cord-022526-j9kg00qf 1811 7 synthesis synthesis NN cord-022526-j9kg00qf 1811 8 and and CC cord-022526-j9kg00qf 1811 9 secretion secretion NN cord-022526-j9kg00qf 1811 10 of of IN cord-022526-j9kg00qf 1811 11 a a DT cord-022526-j9kg00qf 1811 12 number number NN cord-022526-j9kg00qf 1811 13 of of IN cord-022526-j9kg00qf 1811 14 proteins protein NNS cord-022526-j9kg00qf 1811 15 called call VBN cord-022526-j9kg00qf 1811 16 the the DT cord-022526-j9kg00qf 1811 17 acute acute JJ cord-022526-j9kg00qf 1811 18 phase phase NN cord-022526-j9kg00qf 1811 19 proteins protein NNS cord-022526-j9kg00qf 1811 20 increases increase NNS cord-022526-j9kg00qf 1811 21 in in IN cord-022526-j9kg00qf 1811 22 hepatocytes hepatocyte NNS cord-022526-j9kg00qf 1811 23 , , , cord-022526-j9kg00qf 1811 24 whereas whereas IN cord-022526-j9kg00qf 1811 25 synthesis synthesis NN cord-022526-j9kg00qf 1811 26 of of IN cord-022526-j9kg00qf 1811 27 albumin albumin NN cord-022526-j9kg00qf 1811 28 decreases decrease VBZ cord-022526-j9kg00qf 1811 29 . . . cord-022526-j9kg00qf 1812 1 The the DT cord-022526-j9kg00qf 1812 2 primary primary JJ cord-022526-j9kg00qf 1812 3 function function NN cord-022526-j9kg00qf 1812 4 of of IN cord-022526-j9kg00qf 1812 5 this this DT cord-022526-j9kg00qf 1812 6 acute acute JJ cord-022526-j9kg00qf 1812 7 phase phase NN cord-022526-j9kg00qf 1812 8 response response NN cord-022526-j9kg00qf 1812 9 may may MD cord-022526-j9kg00qf 1812 10 be be VB cord-022526-j9kg00qf 1812 11 to to TO cord-022526-j9kg00qf 1812 12 suppress suppress VB cord-022526-j9kg00qf 1812 13 and and CC cord-022526-j9kg00qf 1812 14 contain contain VB cord-022526-j9kg00qf 1812 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 1812 16 responses response NNS cord-022526-j9kg00qf 1812 17 . . . cord-022526-j9kg00qf 1813 1 56 56 CD cord-022526-j9kg00qf 1813 2 IL-6 IL-6 NNP cord-022526-j9kg00qf 1813 3 and and CC cord-022526-j9kg00qf 1813 4 IL-1 IL-1 NNP cord-022526-j9kg00qf 1813 5 are be VBP cord-022526-j9kg00qf 1813 6 the the DT cord-022526-j9kg00qf 1813 7 most most RBS cord-022526-j9kg00qf 1813 8 important important JJ cord-022526-j9kg00qf 1813 9 cytokines cytokine NNS cord-022526-j9kg00qf 1813 10 that that WDT cord-022526-j9kg00qf 1813 11 induce induce VBP cord-022526-j9kg00qf 1813 12 the the DT cord-022526-j9kg00qf 1813 13 acute acute JJ cord-022526-j9kg00qf 1813 14 phase phase NN cord-022526-j9kg00qf 1813 15 response response NN cord-022526-j9kg00qf 1813 16 , , , cord-022526-j9kg00qf 1813 17 90 90 CD cord-022526-j9kg00qf 1813 18 which which WDT cord-022526-j9kg00qf 1813 19 typically typically RB cord-022526-j9kg00qf 1813 20 begins begin VBZ cord-022526-j9kg00qf 1813 21 within within IN cord-022526-j9kg00qf 1813 22 a a DT cord-022526-j9kg00qf 1813 23 few few JJ cord-022526-j9kg00qf 1813 24 hours hour NNS cord-022526-j9kg00qf 1813 25 of of IN cord-022526-j9kg00qf 1813 26 the the DT cord-022526-j9kg00qf 1813 27 insult insult NN cord-022526-j9kg00qf 1813 28 and and CC cord-022526-j9kg00qf 1813 29 subsides subside VBZ cord-022526-j9kg00qf 1813 30 within within IN cord-022526-j9kg00qf 1813 31 24 24 CD cord-022526-j9kg00qf 1813 32 to to TO cord-022526-j9kg00qf 1813 33 48 48 CD cord-022526-j9kg00qf 1813 34 hours hour NNS cord-022526-j9kg00qf 1813 35 , , , cord-022526-j9kg00qf 1813 36 91 91 CD cord-022526-j9kg00qf 1813 37 unless unless IN cord-022526-j9kg00qf 1813 38 the the DT cord-022526-j9kg00qf 1813 39 initiating initiating NN cord-022526-j9kg00qf 1813 40 cause cause NN cord-022526-j9kg00qf 1813 41 persists persist VBZ cord-022526-j9kg00qf 1813 42 . . . cord-022526-j9kg00qf 1814 1 In in IN cord-022526-j9kg00qf 1814 2 horses horse NNS cord-022526-j9kg00qf 1814 3 , , , cord-022526-j9kg00qf 1814 4 fibrinogen fibrinogen NN cord-022526-j9kg00qf 1814 5 ( ( -LRB- cord-022526-j9kg00qf 1814 6 the the DT cord-022526-j9kg00qf 1814 7 most most RBS cord-022526-j9kg00qf 1814 8 commonly commonly RB cord-022526-j9kg00qf 1814 9 evaluated evaluate VBN cord-022526-j9kg00qf 1814 10 ) ) -RRB- cord-022526-j9kg00qf 1814 11 , , , cord-022526-j9kg00qf 1814 12 haptoglobin haptoglobin NN cord-022526-j9kg00qf 1814 13 , , , cord-022526-j9kg00qf 1814 14 transferrin transferrin NN cord-022526-j9kg00qf 1814 15 , , , cord-022526-j9kg00qf 1814 16 ferritin ferritin NN cord-022526-j9kg00qf 1814 17 , , , cord-022526-j9kg00qf 1814 18 ceruloplasmin ceruloplasmin NNP cord-022526-j9kg00qf 1814 19 , , , cord-022526-j9kg00qf 1814 20 coagulation coagulation NN cord-022526-j9kg00qf 1814 21 factor factor NN cord-022526-j9kg00qf 1814 22 VIII VIII NNP cord-022526-j9kg00qf 1814 23 : : : cord-022526-j9kg00qf 1815 1 C C NNP cord-022526-j9kg00qf 1815 2 , , , cord-022526-j9kg00qf 1815 3 serum serum NN cord-022526-j9kg00qf 1815 4 amyloid amyloid NN cord-022526-j9kg00qf 1816 1 A a DT cord-022526-j9kg00qf 1816 2 protein protein NN cord-022526-j9kg00qf 1816 3 , , , cord-022526-j9kg00qf 1816 4 C c NN cord-022526-j9kg00qf 1816 5 - - HYPH cord-022526-j9kg00qf 1816 6 reactive reactive JJ cord-022526-j9kg00qf 1816 7 protein protein NN cord-022526-j9kg00qf 1816 8 , , , cord-022526-j9kg00qf 1816 9 α α NN cord-022526-j9kg00qf 1816 10 1 1 CD cord-022526-j9kg00qf 1816 11 -acid -acid JJ cord-022526-j9kg00qf 1816 12 glycoprotein glycoprotein NN cord-022526-j9kg00qf 1816 13 , , , cord-022526-j9kg00qf 1816 14 and and CC cord-022526-j9kg00qf 1816 15 phospholipase phospholipase NN cord-022526-j9kg00qf 1816 16 A a DT cord-022526-j9kg00qf 1816 17 2 2 CD cord-022526-j9kg00qf 1816 18 are be VBP cord-022526-j9kg00qf 1816 19 considered consider VBN cord-022526-j9kg00qf 1816 20 part part NN cord-022526-j9kg00qf 1816 21 of of IN cord-022526-j9kg00qf 1816 22 the the DT cord-022526-j9kg00qf 1816 23 acute acute JJ cord-022526-j9kg00qf 1816 24 phase phase NN cord-022526-j9kg00qf 1816 25 response response NN cord-022526-j9kg00qf 1816 26 . . . cord-022526-j9kg00qf 1817 1 92 92 CD cord-022526-j9kg00qf 1817 2 One one PRP cord-022526-j9kg00qf 1817 3 must must MD cord-022526-j9kg00qf 1817 4 consider consider VB cord-022526-j9kg00qf 1817 5 the the DT cord-022526-j9kg00qf 1817 6 effect effect NN cord-022526-j9kg00qf 1817 7 of of IN cord-022526-j9kg00qf 1817 8 acute acute JJ cord-022526-j9kg00qf 1817 9 inflammation inflammation NN cord-022526-j9kg00qf 1817 10 on on IN cord-022526-j9kg00qf 1817 11 the the DT cord-022526-j9kg00qf 1817 12 serum serum NN cord-022526-j9kg00qf 1817 13 concentration concentration NN cord-022526-j9kg00qf 1817 14 of of IN cord-022526-j9kg00qf 1817 15 several several JJ cord-022526-j9kg00qf 1817 16 coagulation coagulation NN cord-022526-j9kg00qf 1817 17 factors factor NNS cord-022526-j9kg00qf 1817 18 when when WRB cord-022526-j9kg00qf 1817 19 evaluating evaluate VBG cord-022526-j9kg00qf 1817 20 coagulation coagulation NN cord-022526-j9kg00qf 1817 21 profiles profile NNS cord-022526-j9kg00qf 1817 22 . . . cord-022526-j9kg00qf 1818 1 Serum serum NN cord-022526-j9kg00qf 1818 2 fibrinogen fibrinogen NN cord-022526-j9kg00qf 1818 3 concentration concentration NN cord-022526-j9kg00qf 1818 4 is be VBZ cord-022526-j9kg00qf 1818 5 determined determine VBN cord-022526-j9kg00qf 1818 6 primarily primarily RB cord-022526-j9kg00qf 1818 7 by by IN cord-022526-j9kg00qf 1818 8 the the DT cord-022526-j9kg00qf 1818 9 acute acute JJ cord-022526-j9kg00qf 1818 10 phase phase NN cord-022526-j9kg00qf 1818 11 response response NN cord-022526-j9kg00qf 1818 12 , , , cord-022526-j9kg00qf 1818 13 although although IN cord-022526-j9kg00qf 1818 14 fibrinogen fibrinogen NN cord-022526-j9kg00qf 1818 15 is be VBZ cord-022526-j9kg00qf 1818 16 consumed consume VBN cord-022526-j9kg00qf 1818 17 increasingly increasingly RB cord-022526-j9kg00qf 1818 18 on on IN cord-022526-j9kg00qf 1818 19 activation activation NN cord-022526-j9kg00qf 1818 20 of of IN cord-022526-j9kg00qf 1818 21 the the DT cord-022526-j9kg00qf 1818 22 clotting clotting NN cord-022526-j9kg00qf 1818 23 cascade cascade NN cord-022526-j9kg00qf 1818 24 . . . cord-022526-j9kg00qf 1819 1 Shock shock NN cord-022526-j9kg00qf 1819 2 is be VBZ cord-022526-j9kg00qf 1819 3 characterized characterize VBN cord-022526-j9kg00qf 1819 4 by by IN cord-022526-j9kg00qf 1819 5 a a DT cord-022526-j9kg00qf 1819 6 loss loss NN cord-022526-j9kg00qf 1819 7 of of IN cord-022526-j9kg00qf 1819 8 homeostasis homeostasis NN cord-022526-j9kg00qf 1819 9 attributable attributable JJ cord-022526-j9kg00qf 1819 10 to to IN cord-022526-j9kg00qf 1819 11 breakdown breakdown NN cord-022526-j9kg00qf 1819 12 of of IN cord-022526-j9kg00qf 1819 13 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 1819 14 control control NN cord-022526-j9kg00qf 1819 15 mechanisms mechanism NNS cord-022526-j9kg00qf 1819 16 , , , cord-022526-j9kg00qf 1819 17 decreases decrease VBZ cord-022526-j9kg00qf 1819 18 in in IN cord-022526-j9kg00qf 1819 19 cardiac cardiac JJ cord-022526-j9kg00qf 1819 20 output output NN cord-022526-j9kg00qf 1819 21 and and CC cord-022526-j9kg00qf 1819 22 the the DT cord-022526-j9kg00qf 1819 23 effective effective JJ cord-022526-j9kg00qf 1819 24 circulating circulating NN cord-022526-j9kg00qf 1819 25 volume volume NN cord-022526-j9kg00qf 1819 26 , , , cord-022526-j9kg00qf 1819 27 and and CC cord-022526-j9kg00qf 1819 28 inadequate inadequate JJ cord-022526-j9kg00qf 1819 29 perfusion perfusion NN cord-022526-j9kg00qf 1819 30 of of IN cord-022526-j9kg00qf 1819 31 vital vital JJ cord-022526-j9kg00qf 1819 32 organs organ NNS cord-022526-j9kg00qf 1819 33 . . . cord-022526-j9kg00qf 1820 1 Shock shock NN cord-022526-j9kg00qf 1820 2 caused cause VBN cord-022526-j9kg00qf 1820 3 by by IN cord-022526-j9kg00qf 1820 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1820 5 is be VBZ cord-022526-j9kg00qf 1820 6 classified classify VBN cord-022526-j9kg00qf 1820 7 as as IN cord-022526-j9kg00qf 1820 8 distributive distributive JJ cord-022526-j9kg00qf 1820 9 shock shock NN cord-022526-j9kg00qf 1820 10 93 93 CD cord-022526-j9kg00qf 1820 11 and and CC cord-022526-j9kg00qf 1820 12 is be VBZ cord-022526-j9kg00qf 1820 13 largely largely RB cord-022526-j9kg00qf 1820 14 initiated initiate VBN cord-022526-j9kg00qf 1820 15 by by IN cord-022526-j9kg00qf 1820 16 vascular vascular JJ cord-022526-j9kg00qf 1820 17 dysfunction dysfunction NN cord-022526-j9kg00qf 1820 18 in in IN cord-022526-j9kg00qf 1820 19 the the DT cord-022526-j9kg00qf 1820 20 periphery periphery NN cord-022526-j9kg00qf 1820 21 . . . cord-022526-j9kg00qf 1821 1 Peripheral peripheral JJ cord-022526-j9kg00qf 1821 2 vascular vascular JJ cord-022526-j9kg00qf 1821 3 beds bed NNS cord-022526-j9kg00qf 1821 4 are be VBP cord-022526-j9kg00qf 1821 5 of of IN cord-022526-j9kg00qf 1821 6 major major JJ cord-022526-j9kg00qf 1821 7 importance importance NN cord-022526-j9kg00qf 1821 8 for for IN cord-022526-j9kg00qf 1821 9 the the DT cord-022526-j9kg00qf 1821 10 regulation regulation NN cord-022526-j9kg00qf 1821 11 of of IN cord-022526-j9kg00qf 1821 12 local local JJ cord-022526-j9kg00qf 1821 13 tissue tissue NN cord-022526-j9kg00qf 1821 14 perfusion perfusion NN cord-022526-j9kg00qf 1821 15 and and CC cord-022526-j9kg00qf 1821 16 affect affect VB cord-022526-j9kg00qf 1821 17 systemic systemic JJ cord-022526-j9kg00qf 1821 18 blood blood NN cord-022526-j9kg00qf 1821 19 pressure pressure NN cord-022526-j9kg00qf 1821 20 by by IN cord-022526-j9kg00qf 1821 21 regulating regulate VBG cord-022526-j9kg00qf 1821 22 total total JJ cord-022526-j9kg00qf 1821 23 peripheral peripheral JJ cord-022526-j9kg00qf 1821 24 resistance resistance NN cord-022526-j9kg00qf 1821 25 . . . cord-022526-j9kg00qf 1822 1 Normally normally RB cord-022526-j9kg00qf 1822 2 , , , cord-022526-j9kg00qf 1822 3 vascular vascular JJ cord-022526-j9kg00qf 1822 4 smooth smooth JJ cord-022526-j9kg00qf 1822 5 muscle muscle NN cord-022526-j9kg00qf 1822 6 tone tone NN cord-022526-j9kg00qf 1822 7 is be VBZ cord-022526-j9kg00qf 1822 8 regulated regulate VBN cord-022526-j9kg00qf 1822 9 by by IN cord-022526-j9kg00qf 1822 10 endothelin-1 endothelin-1 NNP cord-022526-j9kg00qf 1822 11 ( ( -LRB- cord-022526-j9kg00qf 1822 12 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 1822 13 ) ) -RRB- cord-022526-j9kg00qf 1822 14 , , , cord-022526-j9kg00qf 1822 15 NO no UH cord-022526-j9kg00qf 1822 16 , , , cord-022526-j9kg00qf 1822 17 and and CC cord-022526-j9kg00qf 1822 18 prostacyclin prostacyclin NNP cord-022526-j9kg00qf 1822 19 ( ( -LRB- cord-022526-j9kg00qf 1822 20 vasodilation vasodilation NN cord-022526-j9kg00qf 1822 21 ) ) -RRB- cord-022526-j9kg00qf 1822 22 released release VBN cord-022526-j9kg00qf 1822 23 from from IN cord-022526-j9kg00qf 1822 24 vascular vascular JJ cord-022526-j9kg00qf 1822 25 endothelial endothelial JJ cord-022526-j9kg00qf 1822 26 cells cell NNS cord-022526-j9kg00qf 1822 27 . . . cord-022526-j9kg00qf 1823 1 94 94 CD cord-022526-j9kg00qf 1824 1 As as IN cord-022526-j9kg00qf 1824 2 mentioned mention VBN cord-022526-j9kg00qf 1824 3 before before RB cord-022526-j9kg00qf 1824 4 , , , cord-022526-j9kg00qf 1824 5 detrimental detrimental JJ cord-022526-j9kg00qf 1824 6 effects effect NNS cord-022526-j9kg00qf 1824 7 of of IN cord-022526-j9kg00qf 1824 8 NO no DT cord-022526-j9kg00qf 1824 9 are be VBP cord-022526-j9kg00qf 1824 10 attributable attributable JJ cord-022526-j9kg00qf 1824 11 to to IN cord-022526-j9kg00qf 1824 12 induction induction NN cord-022526-j9kg00qf 1824 13 of of IN cord-022526-j9kg00qf 1824 14 i i NNP cord-022526-j9kg00qf 1824 15 NOS NOS NNP cord-022526-j9kg00qf 1824 16 in in IN cord-022526-j9kg00qf 1824 17 macrophages macrophage NNS cord-022526-j9kg00qf 1824 18 and and CC cord-022526-j9kg00qf 1824 19 other other JJ cord-022526-j9kg00qf 1824 20 cell cell NN cord-022526-j9kg00qf 1824 21 types type NNS cord-022526-j9kg00qf 1824 22 , , , cord-022526-j9kg00qf 1824 23 rather rather RB cord-022526-j9kg00qf 1824 24 than than IN cord-022526-j9kg00qf 1825 1 endothelialderived endothelialderived NNP cord-022526-j9kg00qf 1826 1 NO no UH cord-022526-j9kg00qf 1826 2 . . . cord-022526-j9kg00qf 1827 1 Peripheral peripheral JJ cord-022526-j9kg00qf 1827 2 vasomotor vasomotor NN cord-022526-j9kg00qf 1827 3 effects effect NNS cord-022526-j9kg00qf 1827 4 of of IN cord-022526-j9kg00qf 1827 5 endotoxin endotoxin NN cord-022526-j9kg00qf 1827 6 manifest manifest NN cord-022526-j9kg00qf 1827 7 as as IN cord-022526-j9kg00qf 1827 8 vasodilation vasodilation NN cord-022526-j9kg00qf 1827 9 and and CC cord-022526-j9kg00qf 1827 10 vasoplegia vasoplegia NN cord-022526-j9kg00qf 1827 11 and and CC cord-022526-j9kg00qf 1827 12 are be VBP cord-022526-j9kg00qf 1827 13 mediated mediate VBN cord-022526-j9kg00qf 1827 14 by by IN cord-022526-j9kg00qf 1827 15 PGI PGI NNP cord-022526-j9kg00qf 1827 16 2 2 CD cord-022526-j9kg00qf 1827 17 , , , cord-022526-j9kg00qf 1827 18 NO no UH cord-022526-j9kg00qf 1827 19 , , , cord-022526-j9kg00qf 1827 20 and and CC cord-022526-j9kg00qf 1827 21 mediators mediator NNS cord-022526-j9kg00qf 1827 22 such such JJ cord-022526-j9kg00qf 1827 23 as as IN cord-022526-j9kg00qf 1827 24 bradykinin bradykinin NN cord-022526-j9kg00qf 1827 25 . . . cord-022526-j9kg00qf 1828 1 Widespread widespread JJ cord-022526-j9kg00qf 1828 2 vasodilation vasodilation NN cord-022526-j9kg00qf 1828 3 leads lead VBZ cord-022526-j9kg00qf 1828 4 to to IN cord-022526-j9kg00qf 1828 5 vascular vascular JJ cord-022526-j9kg00qf 1828 6 blood blood NN cord-022526-j9kg00qf 1828 7 pooling pooling NN cord-022526-j9kg00qf 1828 8 , , , cord-022526-j9kg00qf 1828 9 decentralization decentralization NN cord-022526-j9kg00qf 1828 10 of of IN cord-022526-j9kg00qf 1828 11 blood blood NN cord-022526-j9kg00qf 1828 12 flow flow NN cord-022526-j9kg00qf 1828 13 , , , cord-022526-j9kg00qf 1828 14 decreased decrease VBD cord-022526-j9kg00qf 1828 15 venous venous JJ cord-022526-j9kg00qf 1828 16 return return NN cord-022526-j9kg00qf 1828 17 , , , cord-022526-j9kg00qf 1828 18 and and CC cord-022526-j9kg00qf 1828 19 in in IN cord-022526-j9kg00qf 1828 20 effect effect NN cord-022526-j9kg00qf 1828 21 decreased decrease VBD cord-022526-j9kg00qf 1828 22 effective effective JJ cord-022526-j9kg00qf 1828 23 circulating circulate VBG cord-022526-j9kg00qf 1828 24 volume volume NN cord-022526-j9kg00qf 1828 25 and and CC cord-022526-j9kg00qf 1828 26 cardiac cardiac JJ cord-022526-j9kg00qf 1828 27 output output NN cord-022526-j9kg00qf 1828 28 . . . cord-022526-j9kg00qf 1829 1 93 93 CD cord-022526-j9kg00qf 1830 1 Compensatory compensatory JJ cord-022526-j9kg00qf 1830 2 responses response NNS cord-022526-j9kg00qf 1830 3 in in IN cord-022526-j9kg00qf 1830 4 the the DT cord-022526-j9kg00qf 1830 5 form form NN cord-022526-j9kg00qf 1830 6 of of IN cord-022526-j9kg00qf 1830 7 an an DT cord-022526-j9kg00qf 1830 8 initial initial JJ cord-022526-j9kg00qf 1830 9 hyperdynamic hyperdynamic JJ cord-022526-j9kg00qf 1830 10 phase phase NN cord-022526-j9kg00qf 1830 11 include include VBP cord-022526-j9kg00qf 1830 12 tachycardia tachycardia NN cord-022526-j9kg00qf 1830 13 , , , cord-022526-j9kg00qf 1830 14 increased increase VBN cord-022526-j9kg00qf 1830 15 cardiac cardiac JJ cord-022526-j9kg00qf 1830 16 output output NN cord-022526-j9kg00qf 1830 17 and and CC cord-022526-j9kg00qf 1830 18 central central JJ cord-022526-j9kg00qf 1830 19 venous venous JJ cord-022526-j9kg00qf 1830 20 pressure pressure NN cord-022526-j9kg00qf 1830 21 , , , cord-022526-j9kg00qf 1830 22 pulmonary pulmonary JJ cord-022526-j9kg00qf 1830 23 hypertension hypertension NN cord-022526-j9kg00qf 1830 24 , , , cord-022526-j9kg00qf 1830 25 peripheral peripheral JJ cord-022526-j9kg00qf 1830 26 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 1830 27 , , , cord-022526-j9kg00qf 1830 28 and and CC cord-022526-j9kg00qf 1830 29 increased increase VBD cord-022526-j9kg00qf 1830 30 peripheral peripheral JJ cord-022526-j9kg00qf 1830 31 vascular vascular JJ cord-022526-j9kg00qf 1830 32 resistance resistance NN cord-022526-j9kg00qf 1830 33 . . . cord-022526-j9kg00qf 1831 1 93 93 CD cord-022526-j9kg00qf 1831 2 , , , cord-022526-j9kg00qf 1831 3 95 95 CD cord-022526-j9kg00qf 1831 4 , , , cord-022526-j9kg00qf 1831 5 96 96 CD cord-022526-j9kg00qf 1832 1 The the DT cord-022526-j9kg00qf 1832 2 early early JJ cord-022526-j9kg00qf 1832 3 vasoconstrictive vasoconstrictive JJ cord-022526-j9kg00qf 1832 4 phase phase NN cord-022526-j9kg00qf 1832 5 corresponds correspond VBZ cord-022526-j9kg00qf 1832 6 to to IN cord-022526-j9kg00qf 1832 7 an an DT cord-022526-j9kg00qf 1832 8 increased increase VBN cord-022526-j9kg00qf 1832 9 serum serum NN cord-022526-j9kg00qf 1832 10 concentration concentration NN cord-022526-j9kg00qf 1832 11 of of IN cord-022526-j9kg00qf 1832 12 TXA TXA NNP cord-022526-j9kg00qf 1832 13 2 2 CD cord-022526-j9kg00qf 1832 14 , , , cord-022526-j9kg00qf 1832 15 17 17 CD cord-022526-j9kg00qf 1832 16 but but CC cord-022526-j9kg00qf 1833 1 additional additional JJ cord-022526-j9kg00qf 1833 2 vasoconstrictors vasoconstrictor NNS cord-022526-j9kg00qf 1833 3 such such JJ cord-022526-j9kg00qf 1833 4 as as IN cord-022526-j9kg00qf 1833 5 arginine arginine NN cord-022526-j9kg00qf 1833 6 vasopressin vasopressin NN cord-022526-j9kg00qf 1833 7 , , , cord-022526-j9kg00qf 1833 8 angiotensin angiotensin NN cord-022526-j9kg00qf 1833 9 II II NNP cord-022526-j9kg00qf 1833 10 , , , cord-022526-j9kg00qf 1833 11 serotonin serotonin NN cord-022526-j9kg00qf 1833 12 , , , cord-022526-j9kg00qf 1833 13 endothelin endothelin NN cord-022526-j9kg00qf 1833 14 , , , cord-022526-j9kg00qf 1833 15 and and CC cord-022526-j9kg00qf 1833 16 norepinephrine norepinephrine NN cord-022526-j9kg00qf 1833 17 likely likely RB cord-022526-j9kg00qf 1833 18 are be VBP cord-022526-j9kg00qf 1833 19 implicated implicate VBN cord-022526-j9kg00qf 1833 20 in in IN cord-022526-j9kg00qf 1833 21 the the DT cord-022526-j9kg00qf 1833 22 pathogenesis pathogenesis NN cord-022526-j9kg00qf 1833 23 of of IN cord-022526-j9kg00qf 1833 24 shock shock NN cord-022526-j9kg00qf 1833 25 and and CC cord-022526-j9kg00qf 1833 26 organ organ NN cord-022526-j9kg00qf 1833 27 failure failure NN cord-022526-j9kg00qf 1833 28 . . . cord-022526-j9kg00qf 1834 1 56 56 CD cord-022526-j9kg00qf 1835 1 With with IN cord-022526-j9kg00qf 1835 2 progression progression NN cord-022526-j9kg00qf 1835 3 of of IN cord-022526-j9kg00qf 1835 4 disease disease NN cord-022526-j9kg00qf 1835 5 , , , cord-022526-j9kg00qf 1835 6 the the DT cord-022526-j9kg00qf 1835 7 animal animal NN cord-022526-j9kg00qf 1835 8 enters enter VBZ cord-022526-j9kg00qf 1835 9 a a DT cord-022526-j9kg00qf 1835 10 stage stage NN cord-022526-j9kg00qf 1835 11 of of IN cord-022526-j9kg00qf 1835 12 decompensated decompensated JJ cord-022526-j9kg00qf 1835 13 shock shock NN cord-022526-j9kg00qf 1835 14 and and CC cord-022526-j9kg00qf 1835 15 progressive progressive JJ cord-022526-j9kg00qf 1835 16 systemic systemic JJ cord-022526-j9kg00qf 1835 17 hypotension hypotension NN cord-022526-j9kg00qf 1835 18 , , , cord-022526-j9kg00qf 1835 19 which which WDT cord-022526-j9kg00qf 1835 20 correspond correspond VBP cord-022526-j9kg00qf 1835 21 to to IN cord-022526-j9kg00qf 1835 22 increased increase VBN cord-022526-j9kg00qf 1835 23 plasma plasma NN cord-022526-j9kg00qf 1835 24 concentrations concentration NNS cord-022526-j9kg00qf 1835 25 of of IN cord-022526-j9kg00qf 1835 26 prostacyclin prostacyclin NNP cord-022526-j9kg00qf 1835 27 , , , cord-022526-j9kg00qf 1835 28 PGE PGE NNP cord-022526-j9kg00qf 1835 29 2 2 CD cord-022526-j9kg00qf 1835 30 and and CC cord-022526-j9kg00qf 1835 31 bradykinin bradykinin NN cord-022526-j9kg00qf 1835 32 . . . cord-022526-j9kg00qf 1836 1 17 17 CD cord-022526-j9kg00qf 1836 2 , , , cord-022526-j9kg00qf 1836 3 56 56 CD cord-022526-j9kg00qf 1836 4 Inadequate inadequate JJ cord-022526-j9kg00qf 1836 5 blood blood NN cord-022526-j9kg00qf 1836 6 flow flow NN cord-022526-j9kg00qf 1836 7 and and CC cord-022526-j9kg00qf 1836 8 oxygen oxygen NN cord-022526-j9kg00qf 1836 9 delivery delivery NN cord-022526-j9kg00qf 1836 10 to to IN cord-022526-j9kg00qf 1836 11 tissues tissue NNS cord-022526-j9kg00qf 1836 12 caused cause VBN cord-022526-j9kg00qf 1836 13 by by IN cord-022526-j9kg00qf 1836 14 hypotension hypotension NN cord-022526-j9kg00qf 1836 15 is be VBZ cord-022526-j9kg00qf 1836 16 confounded confound VBN cord-022526-j9kg00qf 1836 17 by by IN cord-022526-j9kg00qf 1836 18 direct direct JJ cord-022526-j9kg00qf 1836 19 myocardial myocardial JJ cord-022526-j9kg00qf 1836 20 suppression suppression NN cord-022526-j9kg00qf 1836 21 via via IN cord-022526-j9kg00qf 1837 1 NO no UH cord-022526-j9kg00qf 1837 2 , , , cord-022526-j9kg00qf 1837 3 93 93 CD cord-022526-j9kg00qf 1837 4 increased increase VBD cord-022526-j9kg00qf 1837 5 vascular vascular JJ cord-022526-j9kg00qf 1837 6 permeability permeability NN cord-022526-j9kg00qf 1837 7 , , , cord-022526-j9kg00qf 1837 8 17 17 CD cord-022526-j9kg00qf 1837 9 intravascular intravascular JJ cord-022526-j9kg00qf 1837 10 microthrombosis microthrombosis NN cord-022526-j9kg00qf 1837 11 , , , cord-022526-j9kg00qf 1837 12 and and CC cord-022526-j9kg00qf 1837 13 impaired impaired JJ cord-022526-j9kg00qf 1837 14 tissue tissue NN cord-022526-j9kg00qf 1837 15 oxygen oxygen NN cord-022526-j9kg00qf 1837 16 extraction extraction NN cord-022526-j9kg00qf 1837 17 93 93 CD cord-022526-j9kg00qf 1837 18 and and CC cord-022526-j9kg00qf 1837 19 results result NNS cord-022526-j9kg00qf 1837 20 in in IN cord-022526-j9kg00qf 1837 21 progressive progressive JJ cord-022526-j9kg00qf 1837 22 metabolic metabolic JJ cord-022526-j9kg00qf 1837 23 acidosis acidosis NN cord-022526-j9kg00qf 1837 24 and and CC cord-022526-j9kg00qf 1837 25 inhibition inhibition NN cord-022526-j9kg00qf 1837 26 of of IN cord-022526-j9kg00qf 1837 27 normal normal JJ cord-022526-j9kg00qf 1837 28 cellular cellular JJ cord-022526-j9kg00qf 1837 29 metabolism metabolism NN cord-022526-j9kg00qf 1837 30 . . . cord-022526-j9kg00qf 1838 1 Quantification quantification NN cord-022526-j9kg00qf 1838 2 of of IN cord-022526-j9kg00qf 1838 3 endotoxin endotoxin NN cord-022526-j9kg00qf 1838 4 in in IN cord-022526-j9kg00qf 1838 5 plasma plasma NN cord-022526-j9kg00qf 1838 6 samples sample NNS cord-022526-j9kg00qf 1838 7 is be VBZ cord-022526-j9kg00qf 1838 8 possible possible JJ cord-022526-j9kg00qf 1838 9 . . . cord-022526-j9kg00qf 1839 1 The the DT cord-022526-j9kg00qf 1839 2 Limulus Limulus NNP cord-022526-j9kg00qf 1839 3 amebocyte amebocyte NN cord-022526-j9kg00qf 1839 4 lysate lysate NN cord-022526-j9kg00qf 1839 5 assay assay NN cord-022526-j9kg00qf 1839 6 is be VBZ cord-022526-j9kg00qf 1839 7 an an DT cord-022526-j9kg00qf 1839 8 activity activity NN cord-022526-j9kg00qf 1839 9 assay assay NN cord-022526-j9kg00qf 1839 10 based base VBN cord-022526-j9kg00qf 1839 11 on on IN cord-022526-j9kg00qf 1839 12 the the DT cord-022526-j9kg00qf 1839 13 endotoxin endotoxin NN cord-022526-j9kg00qf 1839 14 - - HYPH cord-022526-j9kg00qf 1839 15 sensitive sensitive JJ cord-022526-j9kg00qf 1839 16 hemolymph hemolymph NN cord-022526-j9kg00qf 1839 17 coagulation coagulation NN cord-022526-j9kg00qf 1839 18 cascade cascade NN cord-022526-j9kg00qf 1839 19 in in IN cord-022526-j9kg00qf 1839 20 the the DT cord-022526-j9kg00qf 1839 21 horseshoe horseshoe NN cord-022526-j9kg00qf 1839 22 crab crab NN cord-022526-j9kg00qf 1839 23 Limulus Limulus NNP cord-022526-j9kg00qf 1839 24 polyphemus polyphemus NN cord-022526-j9kg00qf 1839 25 . . . cord-022526-j9kg00qf 1840 1 In in IN cord-022526-j9kg00qf 1840 2 Limulus Limulus NNP cord-022526-j9kg00qf 1840 3 this this DT cord-022526-j9kg00qf 1840 4 reaction reaction NN cord-022526-j9kg00qf 1840 5 is be VBZ cord-022526-j9kg00qf 1840 6 thought think VBN cord-022526-j9kg00qf 1840 7 to to TO cord-022526-j9kg00qf 1840 8 be be VB cord-022526-j9kg00qf 1840 9 a a DT cord-022526-j9kg00qf 1840 10 defense defense NN cord-022526-j9kg00qf 1840 11 mechanism mechanism NN cord-022526-j9kg00qf 1840 12 against against IN cord-022526-j9kg00qf 1840 13 gram gram NN cord-022526-j9kg00qf 1840 14 - - HYPH cord-022526-j9kg00qf 1840 15 negative negative JJ cord-022526-j9kg00qf 1840 16 infection infection NN cord-022526-j9kg00qf 1840 17 . . . cord-022526-j9kg00qf 1841 1 97 97 CD cord-022526-j9kg00qf 1842 1 Although although IN cord-022526-j9kg00qf 1842 2 frequently frequently RB cord-022526-j9kg00qf 1842 3 used use VBN cord-022526-j9kg00qf 1842 4 as as IN cord-022526-j9kg00qf 1842 5 a a DT cord-022526-j9kg00qf 1842 6 research research NN cord-022526-j9kg00qf 1842 7 tool tool NN cord-022526-j9kg00qf 1842 8 , , , cord-022526-j9kg00qf 1842 9 the the DT cord-022526-j9kg00qf 1842 10 assay assay NN cord-022526-j9kg00qf 1842 11 is be VBZ cord-022526-j9kg00qf 1842 12 not not RB cord-022526-j9kg00qf 1842 13 convenient convenient JJ cord-022526-j9kg00qf 1842 14 enough enough RB cord-022526-j9kg00qf 1842 15 to to TO cord-022526-j9kg00qf 1842 16 become become VB cord-022526-j9kg00qf 1842 17 a a DT cord-022526-j9kg00qf 1842 18 routine routine JJ cord-022526-j9kg00qf 1842 19 clinical clinical JJ cord-022526-j9kg00qf 1842 20 test test NN cord-022526-j9kg00qf 1842 21 . . . cord-022526-j9kg00qf 1843 1 The the DT cord-022526-j9kg00qf 1843 2 clinician clinician NN cord-022526-j9kg00qf 1843 3 therefore therefore RB cord-022526-j9kg00qf 1843 4 must must MD cord-022526-j9kg00qf 1843 5 appreciate appreciate VB cord-022526-j9kg00qf 1843 6 the the DT cord-022526-j9kg00qf 1843 7 primary primary JJ cord-022526-j9kg00qf 1843 8 disease disease NN cord-022526-j9kg00qf 1843 9 processes process NNS cord-022526-j9kg00qf 1843 10 associated associate VBN cord-022526-j9kg00qf 1843 11 with with IN cord-022526-j9kg00qf 1843 12 a a DT cord-022526-j9kg00qf 1843 13 high high JJ cord-022526-j9kg00qf 1843 14 risk risk NN cord-022526-j9kg00qf 1843 15 of of IN cord-022526-j9kg00qf 1843 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1843 17 and and CC cord-022526-j9kg00qf 1843 18 rely rely VB cord-022526-j9kg00qf 1843 19 on on IN cord-022526-j9kg00qf 1843 20 clinical clinical JJ cord-022526-j9kg00qf 1843 21 signs sign NNS cord-022526-j9kg00qf 1843 22 and and CC cord-022526-j9kg00qf 1843 23 clinicopathologic clinicopathologic NNP cord-022526-j9kg00qf 1843 24 data datum NNS cord-022526-j9kg00qf 1843 25 to to TO cord-022526-j9kg00qf 1843 26 achieve achieve VB cord-022526-j9kg00qf 1843 27 a a DT cord-022526-j9kg00qf 1843 28 diagnosis diagnosis NN cord-022526-j9kg00qf 1843 29 . . . cord-022526-j9kg00qf 1844 1 In in IN cord-022526-j9kg00qf 1844 2 some some DT cord-022526-j9kg00qf 1844 3 cases case NNS cord-022526-j9kg00qf 1844 4 , , , cord-022526-j9kg00qf 1844 5 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1844 6 may may MD cord-022526-j9kg00qf 1844 7 be be VB cord-022526-j9kg00qf 1844 8 the the DT cord-022526-j9kg00qf 1844 9 first first JJ cord-022526-j9kg00qf 1844 10 indication indication NN cord-022526-j9kg00qf 1844 11 of of IN cord-022526-j9kg00qf 1844 12 disease disease NN cord-022526-j9kg00qf 1844 13 or or CC cord-022526-j9kg00qf 1844 14 may may MD cord-022526-j9kg00qf 1844 15 be be VB cord-022526-j9kg00qf 1844 16 the the DT cord-022526-j9kg00qf 1844 17 most most RBS cord-022526-j9kg00qf 1844 18 overt overt JJ cord-022526-j9kg00qf 1844 19 of of IN cord-022526-j9kg00qf 1844 20 otherwise otherwise RB cord-022526-j9kg00qf 1844 21 subtle subtle JJ cord-022526-j9kg00qf 1844 22 clinical clinical JJ cord-022526-j9kg00qf 1844 23 manifestations manifestation NNS cord-022526-j9kg00qf 1844 24 . . . cord-022526-j9kg00qf 1845 1 With with IN cord-022526-j9kg00qf 1845 2 colitis colitis NN cord-022526-j9kg00qf 1845 3 or or CC cord-022526-j9kg00qf 1845 4 proximal proximal JJ cord-022526-j9kg00qf 1845 5 enteritis enteritis NN cord-022526-j9kg00qf 1845 6 , , , cord-022526-j9kg00qf 1845 7 for for IN cord-022526-j9kg00qf 1845 8 example example NN cord-022526-j9kg00qf 1845 9 , , , cord-022526-j9kg00qf 1845 10 one one PRP cord-022526-j9kg00qf 1845 11 may may MD cord-022526-j9kg00qf 1845 12 detect detect VB cord-022526-j9kg00qf 1845 13 signs sign NNS cord-022526-j9kg00qf 1845 14 of of IN cord-022526-j9kg00qf 1845 15 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1845 16 before before IN cord-022526-j9kg00qf 1845 17 the the DT cord-022526-j9kg00qf 1845 18 development development NN cord-022526-j9kg00qf 1845 19 of of IN cord-022526-j9kg00qf 1845 20 colic colic NN cord-022526-j9kg00qf 1845 21 , , , cord-022526-j9kg00qf 1845 22 diarrhea diarrhea NN cord-022526-j9kg00qf 1845 23 , , , cord-022526-j9kg00qf 1845 24 or or CC cord-022526-j9kg00qf 1845 25 gastric gastric JJ cord-022526-j9kg00qf 1845 26 reflux reflux NN cord-022526-j9kg00qf 1845 27 , , , cord-022526-j9kg00qf 1845 28 which which WDT cord-022526-j9kg00qf 1845 29 more more RBR cord-022526-j9kg00qf 1845 30 specifically specifically RB cord-022526-j9kg00qf 1845 31 indicate indicate VBP cord-022526-j9kg00qf 1845 32 the the DT cord-022526-j9kg00qf 1845 33 nature nature NN cord-022526-j9kg00qf 1845 34 of of IN cord-022526-j9kg00qf 1845 35 the the DT cord-022526-j9kg00qf 1845 36 primary primary JJ cord-022526-j9kg00qf 1845 37 illness illness NN cord-022526-j9kg00qf 1845 38 . . . cord-022526-j9kg00qf 1846 1 Diseases disease NNS cord-022526-j9kg00qf 1846 2 such such JJ cord-022526-j9kg00qf 1846 3 as as IN cord-022526-j9kg00qf 1846 4 peritonitis peritonitis NN cord-022526-j9kg00qf 1846 5 or or CC cord-022526-j9kg00qf 1846 6 pleuritis pleuritis NN cord-022526-j9kg00qf 1846 7 , , , cord-022526-j9kg00qf 1846 8 however however RB cord-022526-j9kg00qf 1846 9 , , , cord-022526-j9kg00qf 1846 10 may may MD cord-022526-j9kg00qf 1846 11 show show VB cord-022526-j9kg00qf 1846 12 nonspecific nonspecific JJ cord-022526-j9kg00qf 1846 13 clinical clinical JJ cord-022526-j9kg00qf 1846 14 findings finding NNS cord-022526-j9kg00qf 1846 15 including include VBG cord-022526-j9kg00qf 1846 16 fever fever NN cord-022526-j9kg00qf 1846 17 , , , cord-022526-j9kg00qf 1846 18 anorexia anorexia NN cord-022526-j9kg00qf 1846 19 , , , cord-022526-j9kg00qf 1846 20 and and CC cord-022526-j9kg00qf 1846 21 depression depression NN cord-022526-j9kg00qf 1846 22 . . . cord-022526-j9kg00qf 1847 1 Findings finding NNS cord-022526-j9kg00qf 1847 2 such such JJ cord-022526-j9kg00qf 1847 3 as as IN cord-022526-j9kg00qf 1847 4 neutropenia neutropenia NN cord-022526-j9kg00qf 1847 5 , , , cord-022526-j9kg00qf 1847 6 which which WDT cord-022526-j9kg00qf 1847 7 indicate indicate VBP cord-022526-j9kg00qf 1847 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1847 9 , , , cord-022526-j9kg00qf 1847 10 should should MD cord-022526-j9kg00qf 1847 11 urge urge VB cord-022526-j9kg00qf 1847 12 the the DT cord-022526-j9kg00qf 1847 13 clinician clinician NN cord-022526-j9kg00qf 1847 14 to to TO cord-022526-j9kg00qf 1847 15 search search VB cord-022526-j9kg00qf 1847 16 for for IN cord-022526-j9kg00qf 1847 17 a a DT cord-022526-j9kg00qf 1847 18 septic septic JJ cord-022526-j9kg00qf 1847 19 process process NN cord-022526-j9kg00qf 1847 20 . . . cord-022526-j9kg00qf 1848 1 In in IN cord-022526-j9kg00qf 1848 2 vivo vivo NN cord-022526-j9kg00qf 1848 3 experiments experiment NNS cord-022526-j9kg00qf 1848 4 in in IN cord-022526-j9kg00qf 1848 5 horses horse NNS cord-022526-j9kg00qf 1848 6 clearly clearly RB cord-022526-j9kg00qf 1848 7 show show VBP cord-022526-j9kg00qf 1848 8 that that IN cord-022526-j9kg00qf 1848 9 many many JJ cord-022526-j9kg00qf 1848 10 of of IN cord-022526-j9kg00qf 1848 11 the the DT cord-022526-j9kg00qf 1848 12 clinical clinical JJ cord-022526-j9kg00qf 1848 13 signs sign NNS cord-022526-j9kg00qf 1848 14 associated associate VBN cord-022526-j9kg00qf 1848 15 with with IN cord-022526-j9kg00qf 1848 16 acute acute JJ cord-022526-j9kg00qf 1848 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1848 18 disease disease NN cord-022526-j9kg00qf 1848 19 and and CC cord-022526-j9kg00qf 1848 20 sepsis sepsis NN cord-022526-j9kg00qf 1848 21 are be VBP cord-022526-j9kg00qf 1848 22 attributable attributable JJ cord-022526-j9kg00qf 1848 23 to to IN cord-022526-j9kg00qf 1848 24 the the DT cord-022526-j9kg00qf 1848 25 activities activity NNS cord-022526-j9kg00qf 1848 26 of of IN cord-022526-j9kg00qf 1848 27 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1848 28 and and CC cord-022526-j9kg00qf 1848 29 cytokines cytokine NNS cord-022526-j9kg00qf 1848 30 such such JJ cord-022526-j9kg00qf 1848 31 as as IN cord-022526-j9kg00qf 1848 32 TNF TNF NNP cord-022526-j9kg00qf 1848 33 . . . cord-022526-j9kg00qf 1849 1 On on IN cord-022526-j9kg00qf 1849 2 administration administration NN cord-022526-j9kg00qf 1849 3 of of IN cord-022526-j9kg00qf 1849 4 sublethal sublethal JJ cord-022526-j9kg00qf 1849 5 doses dose NNS cord-022526-j9kg00qf 1849 6 of of IN cord-022526-j9kg00qf 1849 7 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1849 8 the the DT cord-022526-j9kg00qf 1849 9 clinical clinical JJ cord-022526-j9kg00qf 1849 10 response response NN cord-022526-j9kg00qf 1849 11 can can MD cord-022526-j9kg00qf 1849 12 be be VB cord-022526-j9kg00qf 1849 13 divided divide VBN cord-022526-j9kg00qf 1849 14 into into IN cord-022526-j9kg00qf 1849 15 the the DT cord-022526-j9kg00qf 1849 16 early early JJ cord-022526-j9kg00qf 1849 17 hyperdynamic hyperdynamic NN cord-022526-j9kg00qf 1849 18 and and CC cord-022526-j9kg00qf 1849 19 the the DT cord-022526-j9kg00qf 1849 20 later later JJ cord-022526-j9kg00qf 1849 21 hypodynamic hypodynamic NNP cord-022526-j9kg00qf 1849 22 or or CC cord-022526-j9kg00qf 1849 23 shock shock NN cord-022526-j9kg00qf 1849 24 phases phase NNS cord-022526-j9kg00qf 1849 25 . . . cord-022526-j9kg00qf 1850 1 Clinical clinical JJ cord-022526-j9kg00qf 1850 2 signs sign NNS cord-022526-j9kg00qf 1850 3 during during IN cord-022526-j9kg00qf 1850 4 the the DT cord-022526-j9kg00qf 1850 5 first first JJ cord-022526-j9kg00qf 1850 6 phase phase NN cord-022526-j9kg00qf 1850 7 , , , cord-022526-j9kg00qf 1850 8 which which WDT cord-022526-j9kg00qf 1850 9 begins begin VBZ cord-022526-j9kg00qf 1850 10 within within IN cord-022526-j9kg00qf 1850 11 15 15 CD cord-022526-j9kg00qf 1850 12 to to TO cord-022526-j9kg00qf 1850 13 45 45 CD cord-022526-j9kg00qf 1850 14 minutes minute NNS cord-022526-j9kg00qf 1850 15 after after IN cord-022526-j9kg00qf 1850 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1850 17 administration administration NN cord-022526-j9kg00qf 1850 18 , , , cord-022526-j9kg00qf 1850 19 include include VBP cord-022526-j9kg00qf 1850 20 anorexia anorexia NN cord-022526-j9kg00qf 1850 21 , , , cord-022526-j9kg00qf 1850 22 yawning yawning NN cord-022526-j9kg00qf 1850 23 , , , cord-022526-j9kg00qf 1850 24 sweating sweating NN cord-022526-j9kg00qf 1850 25 , , , cord-022526-j9kg00qf 1850 26 depression depression NN cord-022526-j9kg00qf 1850 27 , , , cord-022526-j9kg00qf 1850 28 evidence evidence NN cord-022526-j9kg00qf 1850 29 of of IN cord-022526-j9kg00qf 1850 30 abdominal abdominal JJ cord-022526-j9kg00qf 1850 31 discomfort discomfort NN cord-022526-j9kg00qf 1850 32 , , , cord-022526-j9kg00qf 1850 33 muscle muscle NN cord-022526-j9kg00qf 1850 34 fasciculation fasciculation NN cord-022526-j9kg00qf 1850 35 , , , cord-022526-j9kg00qf 1850 36 and and CC cord-022526-j9kg00qf 1850 37 recumbency recumbency NN cord-022526-j9kg00qf 1850 38 . . . cord-022526-j9kg00qf 1851 1 Heart heart NN cord-022526-j9kg00qf 1851 2 and and CC cord-022526-j9kg00qf 1851 3 respiratory respiratory JJ cord-022526-j9kg00qf 1851 4 rates rate NNS cord-022526-j9kg00qf 1851 5 increase increase VBP cord-022526-j9kg00qf 1851 6 , , , cord-022526-j9kg00qf 1851 7 and and CC cord-022526-j9kg00qf 1851 8 decreased decrease VBD cord-022526-j9kg00qf 1851 9 borborygmi borborygmi NNP cord-022526-j9kg00qf 1851 10 suggest suggest VBP cord-022526-j9kg00qf 1851 11 ileus ileus NNP cord-022526-j9kg00qf 1851 12 . . . cord-022526-j9kg00qf 1852 1 Hyperemia hyperemia NN cord-022526-j9kg00qf 1852 2 of of IN cord-022526-j9kg00qf 1852 3 the the DT cord-022526-j9kg00qf 1852 4 mucous mucous JJ cord-022526-j9kg00qf 1852 5 membranes membrane NNS cord-022526-j9kg00qf 1852 6 and and CC cord-022526-j9kg00qf 1852 7 an an DT cord-022526-j9kg00qf 1852 8 accelerated accelerated JJ cord-022526-j9kg00qf 1852 9 capillary capillary JJ cord-022526-j9kg00qf 1852 10 refill refill NN cord-022526-j9kg00qf 1852 11 time time NN cord-022526-j9kg00qf 1852 12 indicate indicate VBP cord-022526-j9kg00qf 1852 13 the the DT cord-022526-j9kg00qf 1852 14 hyperdynamic hyperdynamic NNP cord-022526-j9kg00qf 1852 15 state state NN cord-022526-j9kg00qf 1852 16 . . . cord-022526-j9kg00qf 1853 1 68 68 CD cord-022526-j9kg00qf 1854 1 If if IN cord-022526-j9kg00qf 1854 2 one one PRP cord-022526-j9kg00qf 1854 3 administers administer VBZ cord-022526-j9kg00qf 1854 4 large large JJ cord-022526-j9kg00qf 1854 5 amounts amount NNS cord-022526-j9kg00qf 1854 6 of of IN cord-022526-j9kg00qf 1854 7 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1854 8 or or CC cord-022526-j9kg00qf 1854 9 if if IN cord-022526-j9kg00qf 1854 10 exposure exposure NN cord-022526-j9kg00qf 1854 11 is be VBZ cord-022526-j9kg00qf 1854 12 ongoing ongoing JJ cord-022526-j9kg00qf 1854 13 , , , cord-022526-j9kg00qf 1854 14 depression depression NN cord-022526-j9kg00qf 1854 15 worsens worsen VBZ cord-022526-j9kg00qf 1854 16 progressively progressively RB cord-022526-j9kg00qf 1854 17 , , , cord-022526-j9kg00qf 1854 18 anorexia anorexia NN cord-022526-j9kg00qf 1854 19 persists persist VBZ cord-022526-j9kg00qf 1854 20 , , , cord-022526-j9kg00qf 1854 21 and and CC cord-022526-j9kg00qf 1854 22 feces fece NNS cord-022526-j9kg00qf 1854 23 develop develop VBP cord-022526-j9kg00qf 1854 24 diarrheic diarrheic NNS cord-022526-j9kg00qf 1854 25 character character NN cord-022526-j9kg00qf 1854 26 . . . cord-022526-j9kg00qf 1855 1 Signs sign NNS cord-022526-j9kg00qf 1855 2 of of IN cord-022526-j9kg00qf 1855 3 colic colic NN cord-022526-j9kg00qf 1855 4 typically typically RB cord-022526-j9kg00qf 1855 5 abate abate VBP cord-022526-j9kg00qf 1855 6 after after IN cord-022526-j9kg00qf 1855 7 the the DT cord-022526-j9kg00qf 1855 8 initial initial JJ cord-022526-j9kg00qf 1855 9 stage stage NN cord-022526-j9kg00qf 1855 10 . . . cord-022526-j9kg00qf 1856 1 Fever fever NN cord-022526-j9kg00qf 1856 2 develops develop VBZ cord-022526-j9kg00qf 1856 3 as as IN cord-022526-j9kg00qf 1856 4 a a DT cord-022526-j9kg00qf 1856 5 result result NN cord-022526-j9kg00qf 1856 6 of of IN cord-022526-j9kg00qf 1856 7 direct direct JJ cord-022526-j9kg00qf 1856 8 action action NN cord-022526-j9kg00qf 1856 9 of of IN cord-022526-j9kg00qf 1856 10 TNF TNF NNP cord-022526-j9kg00qf 1856 11 on on IN cord-022526-j9kg00qf 1856 12 the the DT cord-022526-j9kg00qf 1856 13 thermoregulatory thermoregulatory JJ cord-022526-j9kg00qf 1856 14 center center NN cord-022526-j9kg00qf 1856 15 and and CC cord-022526-j9kg00qf 1856 16 IL-1-induced il-1-induced CD cord-022526-j9kg00qf 1856 17 local local JJ cord-022526-j9kg00qf 1856 18 production production NN cord-022526-j9kg00qf 1856 19 of of IN cord-022526-j9kg00qf 1856 20 PGE PGE NNP cord-022526-j9kg00qf 1856 21 2 2 CD cord-022526-j9kg00qf 1856 22 in in IN cord-022526-j9kg00qf 1856 23 or or CC cord-022526-j9kg00qf 1856 24 near near IN cord-022526-j9kg00qf 1856 25 the the DT cord-022526-j9kg00qf 1856 26 hypothalamus hypothalamus NN cord-022526-j9kg00qf 1856 27 . . . cord-022526-j9kg00qf 1857 1 98 98 CD cord-022526-j9kg00qf 1857 2 , , , cord-022526-j9kg00qf 1857 3 99 99 CD cord-022526-j9kg00qf 1858 1 Because because IN cord-022526-j9kg00qf 1858 2 of of IN cord-022526-j9kg00qf 1858 3 compromised compromise VBN cord-022526-j9kg00qf 1858 4 peripheral peripheral JJ cord-022526-j9kg00qf 1858 5 perfusion perfusion NN cord-022526-j9kg00qf 1858 6 , , , cord-022526-j9kg00qf 1858 7 mucous mucous JJ cord-022526-j9kg00qf 1858 8 membrane membrane NN cord-022526-j9kg00qf 1858 9 color color NN cord-022526-j9kg00qf 1858 10 changes change NNS cord-022526-j9kg00qf 1858 11 to to IN cord-022526-j9kg00qf 1858 12 brick brick VB cord-022526-j9kg00qf 1858 13 red red JJ cord-022526-j9kg00qf 1858 14 or or CC cord-022526-j9kg00qf 1858 15 purple purple NN cord-022526-j9kg00qf 1858 16 , , , cord-022526-j9kg00qf 1858 17 a a DT cord-022526-j9kg00qf 1858 18 dark dark JJ cord-022526-j9kg00qf 1858 19 " " `` cord-022526-j9kg00qf 1858 20 toxic toxic JJ cord-022526-j9kg00qf 1858 21 " " '' cord-022526-j9kg00qf 1858 22 line line NN cord-022526-j9kg00qf 1858 23 appears appear VBZ cord-022526-j9kg00qf 1858 24 , , , cord-022526-j9kg00qf 1858 25 and and CC cord-022526-j9kg00qf 1858 26 capillary capillary JJ cord-022526-j9kg00qf 1858 27 refill refill NN cord-022526-j9kg00qf 1858 28 time time NN cord-022526-j9kg00qf 1858 29 is be VBZ cord-022526-j9kg00qf 1858 30 prolonged prolong VBN cord-022526-j9kg00qf 1858 31 . . . cord-022526-j9kg00qf 1859 1 68 68 CD cord-022526-j9kg00qf 1860 1 Inadequate inadequate JJ cord-022526-j9kg00qf 1860 2 peripheral peripheral JJ cord-022526-j9kg00qf 1860 3 perfusion perfusion NN cord-022526-j9kg00qf 1860 4 and and CC cord-022526-j9kg00qf 1860 5 compromised compromised JJ cord-022526-j9kg00qf 1860 6 organ organ NN cord-022526-j9kg00qf 1860 7 function function NN cord-022526-j9kg00qf 1860 8 finally finally RB cord-022526-j9kg00qf 1860 9 characterize characterize VBP cord-022526-j9kg00qf 1860 10 the the DT cord-022526-j9kg00qf 1860 11 hypodynamic hypodynamic NNP cord-022526-j9kg00qf 1860 12 shock shock NN cord-022526-j9kg00qf 1860 13 phase phase NN cord-022526-j9kg00qf 1860 14 . . . cord-022526-j9kg00qf 1861 1 Body body NN cord-022526-j9kg00qf 1861 2 temperature temperature NN cord-022526-j9kg00qf 1861 3 may may MD cord-022526-j9kg00qf 1861 4 become become VB cord-022526-j9kg00qf 1861 5 subnormal subnormal JJ cord-022526-j9kg00qf 1861 6 and and CC cord-022526-j9kg00qf 1861 7 the the DT cord-022526-j9kg00qf 1861 8 skin skin NN cord-022526-j9kg00qf 1861 9 , , , cord-022526-j9kg00qf 1861 10 especially especially RB cord-022526-j9kg00qf 1861 11 on on IN cord-022526-j9kg00qf 1861 12 extremities extremity NNS cord-022526-j9kg00qf 1861 13 , , , cord-022526-j9kg00qf 1861 14 is be VBZ cord-022526-j9kg00qf 1861 15 cool cool JJ cord-022526-j9kg00qf 1861 16 to to IN cord-022526-j9kg00qf 1861 17 the the DT cord-022526-j9kg00qf 1861 18 touch touch NN cord-022526-j9kg00qf 1861 19 . . . cord-022526-j9kg00qf 1862 1 The the DT cord-022526-j9kg00qf 1862 2 arterial arterial JJ cord-022526-j9kg00qf 1862 3 pulse pulse NN cord-022526-j9kg00qf 1862 4 weakens weaken VBZ cord-022526-j9kg00qf 1862 5 and and CC cord-022526-j9kg00qf 1862 6 venous venous JJ cord-022526-j9kg00qf 1862 7 fill fill NN cord-022526-j9kg00qf 1862 8 is be VBZ cord-022526-j9kg00qf 1862 9 decreased decrease VBN cord-022526-j9kg00qf 1862 10 . . . cord-022526-j9kg00qf 1863 1 Vascular vascular JJ cord-022526-j9kg00qf 1863 2 endothelial endothelial JJ cord-022526-j9kg00qf 1863 3 damage damage NN cord-022526-j9kg00qf 1863 4 and and CC cord-022526-j9kg00qf 1863 5 increased increase VBN cord-022526-j9kg00qf 1863 6 capillary capillary JJ cord-022526-j9kg00qf 1863 7 permeability permeability NN cord-022526-j9kg00qf 1863 8 result result VBP cord-022526-j9kg00qf 1863 9 in in IN cord-022526-j9kg00qf 1863 10 a a DT cord-022526-j9kg00qf 1863 11 muddy muddy JJ cord-022526-j9kg00qf 1863 12 mucous mucous JJ cord-022526-j9kg00qf 1863 13 membrane membrane NN cord-022526-j9kg00qf 1863 14 color color NN cord-022526-j9kg00qf 1863 15 and and CC cord-022526-j9kg00qf 1863 16 diffuse diffuse VB cord-022526-j9kg00qf 1863 17 scleral scleral JJ cord-022526-j9kg00qf 1863 18 reddening reddening NN cord-022526-j9kg00qf 1863 19 . . . cord-022526-j9kg00qf 1864 1 Hemostatic hemostatic NN cord-022526-j9kg00qf 1864 2 abnormalities abnormality NNS cord-022526-j9kg00qf 1864 3 can can MD cord-022526-j9kg00qf 1864 4 manifest manifest VB cord-022526-j9kg00qf 1864 5 in in IN cord-022526-j9kg00qf 1864 6 the the DT cord-022526-j9kg00qf 1864 7 form form NN cord-022526-j9kg00qf 1864 8 of of IN cord-022526-j9kg00qf 1864 9 thrombosis thrombosis NN cord-022526-j9kg00qf 1864 10 , , , cord-022526-j9kg00qf 1864 11 such such JJ cord-022526-j9kg00qf 1864 12 as as IN cord-022526-j9kg00qf 1864 13 of of IN cord-022526-j9kg00qf 1864 14 the the DT cord-022526-j9kg00qf 1864 15 jugular jugular NN cord-022526-j9kg00qf 1864 16 vein vein NN cord-022526-j9kg00qf 1864 17 , , , cord-022526-j9kg00qf 1864 18 or or CC cord-022526-j9kg00qf 1864 19 increased increase VBN cord-022526-j9kg00qf 1864 20 bleeding bleed VBG cord-022526-j9kg00qf 1864 21 tendency tendency NN cord-022526-j9kg00qf 1864 22 with with IN cord-022526-j9kg00qf 1864 23 mucosal mucosal JJ cord-022526-j9kg00qf 1864 24 petechiation petechiation NN cord-022526-j9kg00qf 1864 25 or or CC cord-022526-j9kg00qf 1864 26 ecchymoses ecchymosis NNS cord-022526-j9kg00qf 1864 27 and and CC cord-022526-j9kg00qf 1864 28 prolonged prolong VBN cord-022526-j9kg00qf 1864 29 bleeding bleeding NN cord-022526-j9kg00qf 1864 30 from from IN cord-022526-j9kg00qf 1864 31 venipuncture venipuncture NN cord-022526-j9kg00qf 1864 32 sites site NNS cord-022526-j9kg00qf 1864 33 . . . cord-022526-j9kg00qf 1865 1 74 74 CD cord-022526-j9kg00qf 1865 2 Bleeding bleed VBG cord-022526-j9kg00qf 1865 3 also also RB cord-022526-j9kg00qf 1865 4 may may MD cord-022526-j9kg00qf 1865 5 occur occur VB cord-022526-j9kg00qf 1865 6 in in IN cord-022526-j9kg00qf 1865 7 spontaneous spontaneous JJ cord-022526-j9kg00qf 1865 8 epistaxis epistaxis NN cord-022526-j9kg00qf 1865 9 or or CC cord-022526-j9kg00qf 1865 10 prolonged prolong VBN cord-022526-j9kg00qf 1865 11 hemorrhage hemorrhage NN cord-022526-j9kg00qf 1865 12 after after IN cord-022526-j9kg00qf 1865 13 nasogastric nasogastric NN cord-022526-j9kg00qf 1865 14 intubation intubation NN cord-022526-j9kg00qf 1865 15 . . . cord-022526-j9kg00qf 1866 1 17 17 CD cord-022526-j9kg00qf 1866 2 Additional additional JJ cord-022526-j9kg00qf 1866 3 clinical clinical JJ cord-022526-j9kg00qf 1866 4 signs sign NNS cord-022526-j9kg00qf 1866 5 typically typically RB cord-022526-j9kg00qf 1866 6 reflect reflect VBP cord-022526-j9kg00qf 1866 7 the the DT cord-022526-j9kg00qf 1866 8 development development NN cord-022526-j9kg00qf 1866 9 of of IN cord-022526-j9kg00qf 1866 10 organ organ NN cord-022526-j9kg00qf 1866 11 failure failure NN cord-022526-j9kg00qf 1866 12 . . . cord-022526-j9kg00qf 1867 1 Renal renal JJ cord-022526-j9kg00qf 1867 2 failure failure NN cord-022526-j9kg00qf 1867 3 and and CC cord-022526-j9kg00qf 1867 4 laminitis laminitis NN cord-022526-j9kg00qf 1867 5 appear appear VBP cord-022526-j9kg00qf 1867 6 to to TO cord-022526-j9kg00qf 1867 7 be be VB cord-022526-j9kg00qf 1867 8 common common JJ cord-022526-j9kg00qf 1867 9 complications complication NNS cord-022526-j9kg00qf 1867 10 of of IN cord-022526-j9kg00qf 1867 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1867 12 in in IN cord-022526-j9kg00qf 1867 13 horses horse NNS cord-022526-j9kg00qf 1867 14 . . . cord-022526-j9kg00qf 1868 1 Renal renal JJ cord-022526-j9kg00qf 1868 2 failure failure NN cord-022526-j9kg00qf 1868 3 results result NNS cord-022526-j9kg00qf 1868 4 from from IN cord-022526-j9kg00qf 1868 5 ischemic ischemic JJ cord-022526-j9kg00qf 1868 6 cortical cortical JJ cord-022526-j9kg00qf 1868 7 necrosis necrosis NN cord-022526-j9kg00qf 1868 8 and and CC cord-022526-j9kg00qf 1868 9 acute acute JJ cord-022526-j9kg00qf 1868 10 tubular tubular JJ cord-022526-j9kg00qf 1868 11 necrosis necrosis NN cord-022526-j9kg00qf 1868 12 caused cause VBN cord-022526-j9kg00qf 1868 13 by by IN cord-022526-j9kg00qf 1868 14 coagulopathy coagulopathy NN cord-022526-j9kg00qf 1868 15 - - HYPH cord-022526-j9kg00qf 1868 16 induced induce VBN cord-022526-j9kg00qf 1868 17 afferent afferent JJ cord-022526-j9kg00qf 1868 18 arteriolar arteriolar JJ cord-022526-j9kg00qf 1868 19 obstruction obstruction NN cord-022526-j9kg00qf 1868 20 . . . cord-022526-j9kg00qf 1869 1 Clinical clinical JJ cord-022526-j9kg00qf 1869 2 signs sign NNS cord-022526-j9kg00qf 1869 3 may may MD cord-022526-j9kg00qf 1869 4 include include VB cord-022526-j9kg00qf 1869 5 oliguria oliguria NNP cord-022526-j9kg00qf 1869 6 , , , cord-022526-j9kg00qf 1869 7 anuria anuria NNP cord-022526-j9kg00qf 1869 8 , , , cord-022526-j9kg00qf 1869 9 or or CC cord-022526-j9kg00qf 1869 10 hematuria hematuria NN cord-022526-j9kg00qf 1869 11 caused cause VBN cord-022526-j9kg00qf 1869 12 by by IN cord-022526-j9kg00qf 1869 13 renal renal JJ cord-022526-j9kg00qf 1869 14 infarction infarction NN cord-022526-j9kg00qf 1869 15 . . . cord-022526-j9kg00qf 1870 1 Laminitis Laminitis NNP cord-022526-j9kg00qf 1870 2 may may MD cord-022526-j9kg00qf 1870 3 lead lead VB cord-022526-j9kg00qf 1870 4 to to IN cord-022526-j9kg00qf 1870 5 lameness lameness NN cord-022526-j9kg00qf 1870 6 , , , cord-022526-j9kg00qf 1870 7 increased increase VBN cord-022526-j9kg00qf 1870 8 digital digital JJ cord-022526-j9kg00qf 1870 9 arterial arterial JJ cord-022526-j9kg00qf 1870 10 pulsation pulsation NN cord-022526-j9kg00qf 1870 11 , , , cord-022526-j9kg00qf 1870 12 increased increase VBN cord-022526-j9kg00qf 1870 13 warmth warmth NN cord-022526-j9kg00qf 1870 14 of of IN cord-022526-j9kg00qf 1870 15 the the DT cord-022526-j9kg00qf 1870 16 hoof hoof NN cord-022526-j9kg00qf 1870 17 wall wall NN cord-022526-j9kg00qf 1870 18 , , , cord-022526-j9kg00qf 1870 19 and and CC cord-022526-j9kg00qf 1870 20 sensitivity sensitivity NN cord-022526-j9kg00qf 1870 21 to to IN cord-022526-j9kg00qf 1870 22 hoof hoof NN cord-022526-j9kg00qf 1870 23 tester tester NN cord-022526-j9kg00qf 1870 24 pressure pressure NN cord-022526-j9kg00qf 1870 25 . . . cord-022526-j9kg00qf 1871 1 Other other JJ cord-022526-j9kg00qf 1871 2 signs sign NNS cord-022526-j9kg00qf 1871 3 of of IN cord-022526-j9kg00qf 1871 4 organ organ NN cord-022526-j9kg00qf 1871 5 failure failure NN cord-022526-j9kg00qf 1871 6 include include VBP cord-022526-j9kg00qf 1871 7 icterus icterus NN cord-022526-j9kg00qf 1871 8 , , , cord-022526-j9kg00qf 1871 9 anorexia anorexia NN cord-022526-j9kg00qf 1871 10 and and CC cord-022526-j9kg00qf 1871 11 depression depression NN cord-022526-j9kg00qf 1871 12 caused cause VBN cord-022526-j9kg00qf 1871 13 by by IN cord-022526-j9kg00qf 1871 14 liver liver NN cord-022526-j9kg00qf 1871 15 failure failure NN cord-022526-j9kg00qf 1871 16 , , , cord-022526-j9kg00qf 1871 17 74 74 CD cord-022526-j9kg00qf 1871 18 tachypnea tachypnea NN cord-022526-j9kg00qf 1871 19 and and CC cord-022526-j9kg00qf 1871 20 dyspnea dyspnea NN cord-022526-j9kg00qf 1871 21 caused cause VBN cord-022526-j9kg00qf 1871 22 by by IN cord-022526-j9kg00qf 1871 23 pulmonary pulmonary JJ cord-022526-j9kg00qf 1871 24 failure failure NN cord-022526-j9kg00qf 1871 25 , , , cord-022526-j9kg00qf 1871 26 colic colic NN cord-022526-j9kg00qf 1871 27 and and CC cord-022526-j9kg00qf 1871 28 bleeding bleeding NN cord-022526-j9kg00qf 1871 29 caused cause VBN cord-022526-j9kg00qf 1871 30 by by IN cord-022526-j9kg00qf 1871 31 ischemia ischemia NN cord-022526-j9kg00qf 1871 32 - - HYPH cord-022526-j9kg00qf 1871 33 induced induce VBN cord-022526-j9kg00qf 1871 34 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1871 35 ulceration ulceration NN cord-022526-j9kg00qf 1871 36 and and CC cord-022526-j9kg00qf 1871 37 abnormal abnormal JJ cord-022526-j9kg00qf 1871 38 motility motility NN cord-022526-j9kg00qf 1871 39 patterns pattern NNS cord-022526-j9kg00qf 1871 40 , , , cord-022526-j9kg00qf 1871 41 17 17 CD cord-022526-j9kg00qf 1871 42 and and CC cord-022526-j9kg00qf 1871 43 persistent persistent JJ cord-022526-j9kg00qf 1871 44 tachycardia tachycardia NN cord-022526-j9kg00qf 1871 45 or or CC cord-022526-j9kg00qf 1871 46 cardiac cardiac JJ cord-022526-j9kg00qf 1871 47 arrhythmia arrhythmia NN cord-022526-j9kg00qf 1871 48 in in IN cord-022526-j9kg00qf 1871 49 cases case NNS cord-022526-j9kg00qf 1871 50 of of IN cord-022526-j9kg00qf 1871 51 cardiac cardiac JJ cord-022526-j9kg00qf 1871 52 failure failure NN cord-022526-j9kg00qf 1871 53 . . . cord-022526-j9kg00qf 1872 1 In in IN cord-022526-j9kg00qf 1872 2 pregnant pregnant JJ cord-022526-j9kg00qf 1872 3 mares mare NNS cord-022526-j9kg00qf 1872 4 , , , cord-022526-j9kg00qf 1872 5 fetal fetal JJ cord-022526-j9kg00qf 1872 6 death death NN cord-022526-j9kg00qf 1872 7 and and CC cord-022526-j9kg00qf 1872 8 abortion abortion NN cord-022526-j9kg00qf 1872 9 can can MD cord-022526-j9kg00qf 1872 10 occur occur VB cord-022526-j9kg00qf 1872 11 because because IN cord-022526-j9kg00qf 1872 12 of of IN cord-022526-j9kg00qf 1872 13 increased increase VBN cord-022526-j9kg00qf 1872 14 production production NN cord-022526-j9kg00qf 1872 15 of of IN cord-022526-j9kg00qf 1872 16 PGF PGF NNP cord-022526-j9kg00qf 1872 17 2α 2α CD cord-022526-j9kg00qf 1872 18 and and CC cord-022526-j9kg00qf 1872 19 decreased decrease VBD cord-022526-j9kg00qf 1872 20 serum serum NN cord-022526-j9kg00qf 1872 21 progesterone progesterone NN cord-022526-j9kg00qf 1872 22 concentrations concentration NNS cord-022526-j9kg00qf 1872 23 . . . cord-022526-j9kg00qf 1873 1 100 100 CD cord-022526-j9kg00qf 1873 2 , , , cord-022526-j9kg00qf 1873 3 101 101 CD cord-022526-j9kg00qf 1873 4 _SP cord-022526-j9kg00qf 1873 5 Alterations alteration NNS cord-022526-j9kg00qf 1873 6 in in IN cord-022526-j9kg00qf 1873 7 the the DT cord-022526-j9kg00qf 1873 8 hemogram hemogram NN cord-022526-j9kg00qf 1873 9 and and CC cord-022526-j9kg00qf 1873 10 serum serum NN cord-022526-j9kg00qf 1873 11 biochemical biochemical JJ cord-022526-j9kg00qf 1873 12 profile profile NN cord-022526-j9kg00qf 1873 13 are be VBP cord-022526-j9kg00qf 1873 14 nonspecific nonspecific JJ cord-022526-j9kg00qf 1873 15 and and CC cord-022526-j9kg00qf 1873 16 mainly mainly RB cord-022526-j9kg00qf 1873 17 reflect reflect VB cord-022526-j9kg00qf 1873 18 the the DT cord-022526-j9kg00qf 1873 19 underlying underlie VBG cord-022526-j9kg00qf 1873 20 disease disease NN cord-022526-j9kg00qf 1873 21 process process NN cord-022526-j9kg00qf 1873 22 and and CC cord-022526-j9kg00qf 1873 23 the the DT cord-022526-j9kg00qf 1873 24 occurrence occurrence NN cord-022526-j9kg00qf 1873 25 of of IN cord-022526-j9kg00qf 1873 26 organ organ NN cord-022526-j9kg00qf 1873 27 failure failure NN cord-022526-j9kg00qf 1873 28 . . . cord-022526-j9kg00qf 1874 1 Leukopenia leukopenia NN cord-022526-j9kg00qf 1874 2 caused cause VBN cord-022526-j9kg00qf 1874 3 by by IN cord-022526-j9kg00qf 1874 4 neutropenia neutropenia NN cord-022526-j9kg00qf 1874 5 may may MD cord-022526-j9kg00qf 1874 6 be be VB cord-022526-j9kg00qf 1874 7 the the DT cord-022526-j9kg00qf 1874 8 most most RBS cord-022526-j9kg00qf 1874 9 specific specific JJ cord-022526-j9kg00qf 1874 10 indicator indicator NN cord-022526-j9kg00qf 1874 11 of of IN cord-022526-j9kg00qf 1874 12 acute acute JJ cord-022526-j9kg00qf 1874 13 bacterial bacterial JJ cord-022526-j9kg00qf 1874 14 sepsis sepsis NN cord-022526-j9kg00qf 1874 15 or or CC cord-022526-j9kg00qf 1874 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1874 17 . . . cord-022526-j9kg00qf 1875 1 68 68 CD cord-022526-j9kg00qf 1876 1 In in IN cord-022526-j9kg00qf 1876 2 prolonged prolonged JJ cord-022526-j9kg00qf 1876 3 cases case NNS cord-022526-j9kg00qf 1876 4 , , , cord-022526-j9kg00qf 1876 5 an an DT cord-022526-j9kg00qf 1876 6 increased increase VBN cord-022526-j9kg00qf 1876 7 proportion proportion NN cord-022526-j9kg00qf 1876 8 of of IN cord-022526-j9kg00qf 1876 9 immature immature JJ cord-022526-j9kg00qf 1876 10 neutrophil neutrophil NN cord-022526-j9kg00qf 1876 11 forms form NNS cord-022526-j9kg00qf 1876 12 ( ( -LRB- cord-022526-j9kg00qf 1876 13 bands band NNS cord-022526-j9kg00qf 1876 14 ) ) -RRB- cord-022526-j9kg00qf 1876 15 and and CC cord-022526-j9kg00qf 1876 16 toxic toxic JJ cord-022526-j9kg00qf 1876 17 changes change NNS cord-022526-j9kg00qf 1876 18 are be VBP cord-022526-j9kg00qf 1876 19 observable observable JJ cord-022526-j9kg00qf 1876 20 . . . cord-022526-j9kg00qf 1877 1 Toxic toxic JJ cord-022526-j9kg00qf 1877 2 changes change NNS cord-022526-j9kg00qf 1877 3 resulting result VBG cord-022526-j9kg00qf 1877 4 from from IN cord-022526-j9kg00qf 1877 5 neutrophil neutrophil NN cord-022526-j9kg00qf 1877 6 activation activation NN cord-022526-j9kg00qf 1877 7 include include VBP cord-022526-j9kg00qf 1877 8 vacuolation vacuolation NN cord-022526-j9kg00qf 1877 9 , , , cord-022526-j9kg00qf 1877 10 cytoplasmic cytoplasmic JJ cord-022526-j9kg00qf 1877 11 granulation granulation NN cord-022526-j9kg00qf 1877 12 , , , cord-022526-j9kg00qf 1877 13 basophilic basophilic NNP cord-022526-j9kg00qf 1877 14 cytoplasm cytoplasm NNP cord-022526-j9kg00qf 1877 15 , , , cord-022526-j9kg00qf 1877 16 and and CC cord-022526-j9kg00qf 1877 17 Döhle Döhle NNP cord-022526-j9kg00qf 1877 18 's 's POS cord-022526-j9kg00qf 1877 19 bodies body NNS cord-022526-j9kg00qf 1877 20 . . . cord-022526-j9kg00qf 1878 1 Because because IN cord-022526-j9kg00qf 1878 2 neutropenia neutropenia NN cord-022526-j9kg00qf 1878 3 occurs occur VBZ cord-022526-j9kg00qf 1878 4 early early RB cord-022526-j9kg00qf 1878 5 in in IN cord-022526-j9kg00qf 1878 6 the the DT cord-022526-j9kg00qf 1878 7 development development NN cord-022526-j9kg00qf 1878 8 of of IN cord-022526-j9kg00qf 1878 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1878 10 , , , cord-022526-j9kg00qf 1878 11 it -PRON- PRP cord-022526-j9kg00qf 1878 12 also also RB cord-022526-j9kg00qf 1878 13 may may MD cord-022526-j9kg00qf 1878 14 be be VB cord-022526-j9kg00qf 1878 15 a a DT cord-022526-j9kg00qf 1878 16 useful useful JJ cord-022526-j9kg00qf 1878 17 parameter parameter NN cord-022526-j9kg00qf 1878 18 for for IN cord-022526-j9kg00qf 1878 19 monitoring monitor VBG cord-022526-j9kg00qf 1878 20 horses horse NNS cord-022526-j9kg00qf 1878 21 at at IN cord-022526-j9kg00qf 1878 22 risk risk NN cord-022526-j9kg00qf 1878 23 . . . cord-022526-j9kg00qf 1879 1 68 68 CD cord-022526-j9kg00qf 1880 1 On on IN cord-022526-j9kg00qf 1880 2 recovery recovery NN cord-022526-j9kg00qf 1880 3 , , , cord-022526-j9kg00qf 1880 4 neutropenia neutropenia NN cord-022526-j9kg00qf 1880 5 typically typically RB cord-022526-j9kg00qf 1880 6 is be VBZ cord-022526-j9kg00qf 1880 7 followed follow VBN cord-022526-j9kg00qf 1880 8 by by IN cord-022526-j9kg00qf 1880 9 a a DT cord-022526-j9kg00qf 1880 10 pronounced pronounce VBN cord-022526-j9kg00qf 1880 11 rebound rebound NN cord-022526-j9kg00qf 1880 12 neutrophilia neutrophilia NNP cord-022526-j9kg00qf 1880 13 . . . cord-022526-j9kg00qf 1881 1 An an DT cord-022526-j9kg00qf 1881 2 elevated elevated JJ cord-022526-j9kg00qf 1881 3 hematocrit hematocrit NN cord-022526-j9kg00qf 1881 4 and and CC cord-022526-j9kg00qf 1881 5 total total JJ cord-022526-j9kg00qf 1881 6 serum serum NN cord-022526-j9kg00qf 1881 7 protein protein NN cord-022526-j9kg00qf 1881 8 concentration concentration NN cord-022526-j9kg00qf 1881 9 are be VBP cord-022526-j9kg00qf 1881 10 evidence evidence NN cord-022526-j9kg00qf 1881 11 of of IN cord-022526-j9kg00qf 1881 12 dehydration dehydration NN cord-022526-j9kg00qf 1881 13 ; ; : cord-022526-j9kg00qf 1881 14 however however RB cord-022526-j9kg00qf 1881 15 , , , cord-022526-j9kg00qf 1881 16 splenic splenic JJ cord-022526-j9kg00qf 1881 17 contraction contraction NN cord-022526-j9kg00qf 1881 18 caused cause VBN cord-022526-j9kg00qf 1881 19 by by IN cord-022526-j9kg00qf 1881 20 increased increase VBN cord-022526-j9kg00qf 1881 21 sympathetic sympathetic JJ cord-022526-j9kg00qf 1881 22 stimulation stimulation NN cord-022526-j9kg00qf 1881 23 and and CC cord-022526-j9kg00qf 1881 24 protein protein NN cord-022526-j9kg00qf 1881 25 losses loss NNS cord-022526-j9kg00qf 1881 26 also also RB cord-022526-j9kg00qf 1881 27 influence influence VBP cord-022526-j9kg00qf 1881 28 these these DT cord-022526-j9kg00qf 1881 29 parameters parameter NNS cord-022526-j9kg00qf 1881 30 . . . cord-022526-j9kg00qf 1882 1 A a DT cord-022526-j9kg00qf 1882 2 normal normal JJ cord-022526-j9kg00qf 1882 3 or or CC cord-022526-j9kg00qf 1882 4 only only RB cord-022526-j9kg00qf 1882 5 slightly slightly RB cord-022526-j9kg00qf 1882 6 decreased decrease VBD cord-022526-j9kg00qf 1882 7 serum serum NN cord-022526-j9kg00qf 1882 8 protein protein NN cord-022526-j9kg00qf 1882 9 and and CC cord-022526-j9kg00qf 1882 10 albumin albumin NN cord-022526-j9kg00qf 1882 11 concentration concentration NN cord-022526-j9kg00qf 1882 12 in in IN cord-022526-j9kg00qf 1882 13 the the DT cord-022526-j9kg00qf 1882 14 face face NN cord-022526-j9kg00qf 1882 15 of of IN cord-022526-j9kg00qf 1882 16 an an DT cord-022526-j9kg00qf 1882 17 elevated elevated JJ cord-022526-j9kg00qf 1882 18 hematocrit hematocrit NN cord-022526-j9kg00qf 1882 19 and and CC cord-022526-j9kg00qf 1882 20 clinical clinical JJ cord-022526-j9kg00qf 1882 21 signs sign NNS cord-022526-j9kg00qf 1882 22 of of IN cord-022526-j9kg00qf 1882 23 dehydration dehydration NN cord-022526-j9kg00qf 1882 24 should should MD cord-022526-j9kg00qf 1882 25 alert alert VB cord-022526-j9kg00qf 1882 26 the the DT cord-022526-j9kg00qf 1882 27 clinician clinician NN cord-022526-j9kg00qf 1882 28 to to IN cord-022526-j9kg00qf 1882 29 the the DT cord-022526-j9kg00qf 1882 30 possibility possibility NN cord-022526-j9kg00qf 1882 31 of of IN cord-022526-j9kg00qf 1882 32 protein protein NN cord-022526-j9kg00qf 1882 33 loss loss NN cord-022526-j9kg00qf 1882 34 . . . cord-022526-j9kg00qf 1883 1 Hypoproteinemia Hypoproteinemia NNP cord-022526-j9kg00qf 1883 2 and and CC cord-022526-j9kg00qf 1883 3 hypoalbuminemia hypoalbuminemia NNP cord-022526-j9kg00qf 1883 4 can can MD cord-022526-j9kg00qf 1883 5 occur occur VB cord-022526-j9kg00qf 1883 6 because because IN cord-022526-j9kg00qf 1883 7 of of IN cord-022526-j9kg00qf 1883 8 loss loss NN cord-022526-j9kg00qf 1883 9 via via IN cord-022526-j9kg00qf 1883 10 the the DT cord-022526-j9kg00qf 1883 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1883 12 or or CC cord-022526-j9kg00qf 1883 13 urinary urinary JJ cord-022526-j9kg00qf 1883 14 tract tract NN cord-022526-j9kg00qf 1883 15 or or CC cord-022526-j9kg00qf 1883 16 with with IN cord-022526-j9kg00qf 1883 17 pleural pleural JJ cord-022526-j9kg00qf 1883 18 or or CC cord-022526-j9kg00qf 1883 19 peritoneal peritoneal JJ cord-022526-j9kg00qf 1883 20 cavity cavity NN cord-022526-j9kg00qf 1883 21 effusion effusion NN cord-022526-j9kg00qf 1883 22 . . . cord-022526-j9kg00qf 1884 1 Increased increase VBN cord-022526-j9kg00qf 1884 2 vascular vascular JJ cord-022526-j9kg00qf 1884 3 permeability permeability NN cord-022526-j9kg00qf 1884 4 and and CC cord-022526-j9kg00qf 1884 5 edema edema NN cord-022526-j9kg00qf 1884 6 formation formation NN cord-022526-j9kg00qf 1884 7 contribute contribute VBP cord-022526-j9kg00qf 1884 8 to to IN cord-022526-j9kg00qf 1884 9 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 1884 10 . . . cord-022526-j9kg00qf 1885 1 Serum serum NN cord-022526-j9kg00qf 1885 2 electrolyte electrolyte NN cord-022526-j9kg00qf 1885 3 abnormalities abnormality NNS cord-022526-j9kg00qf 1885 4 primarily primarily RB cord-022526-j9kg00qf 1885 5 depend depend VBP cord-022526-j9kg00qf 1885 6 on on IN cord-022526-j9kg00qf 1885 7 the the DT cord-022526-j9kg00qf 1885 8 nature nature NN cord-022526-j9kg00qf 1885 9 and and CC cord-022526-j9kg00qf 1885 10 duration duration NN cord-022526-j9kg00qf 1885 11 of of IN cord-022526-j9kg00qf 1885 12 underlying underlie VBG cord-022526-j9kg00qf 1885 13 disease disease NN cord-022526-j9kg00qf 1885 14 processes process NNS cord-022526-j9kg00qf 1885 15 and and CC cord-022526-j9kg00qf 1885 16 need need VBP cord-022526-j9kg00qf 1885 17 to to TO cord-022526-j9kg00qf 1885 18 be be VB cord-022526-j9kg00qf 1885 19 evaluated evaluate VBN cord-022526-j9kg00qf 1885 20 individually individually RB cord-022526-j9kg00qf 1885 21 . . . cord-022526-j9kg00qf 1886 1 Common common JJ cord-022526-j9kg00qf 1886 2 sources source NNS cord-022526-j9kg00qf 1886 3 of of IN cord-022526-j9kg00qf 1886 4 electrolyte electrolyte JJ cord-022526-j9kg00qf 1886 5 loss loss NN cord-022526-j9kg00qf 1886 6 are be VBP cord-022526-j9kg00qf 1886 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1886 8 secretions secretion NNS cord-022526-j9kg00qf 1886 9 , , , cord-022526-j9kg00qf 1886 10 urine urine NN cord-022526-j9kg00qf 1886 11 , , , cord-022526-j9kg00qf 1886 12 and and CC cord-022526-j9kg00qf 1886 13 sweat sweat NN cord-022526-j9kg00qf 1886 14 ; ; : cord-022526-j9kg00qf 1886 15 however however RB cord-022526-j9kg00qf 1886 16 , , , cord-022526-j9kg00qf 1886 17 severe severe JJ cord-022526-j9kg00qf 1886 18 effusion effusion NN cord-022526-j9kg00qf 1886 19 into into IN cord-022526-j9kg00qf 1886 20 body body NN cord-022526-j9kg00qf 1886 21 cavities cavity NNS cord-022526-j9kg00qf 1886 22 may may MD cord-022526-j9kg00qf 1886 23 contribute contribute VB cord-022526-j9kg00qf 1886 24 . . . cord-022526-j9kg00qf 1887 1 In in IN cord-022526-j9kg00qf 1887 2 anorexic anorexic JJ cord-022526-j9kg00qf 1887 3 patients patient NNS cord-022526-j9kg00qf 1887 4 , , , cord-022526-j9kg00qf 1887 5 lack lack NN cord-022526-j9kg00qf 1887 6 of of IN cord-022526-j9kg00qf 1887 7 dietary dietary JJ cord-022526-j9kg00qf 1887 8 intake intake NN cord-022526-j9kg00qf 1887 9 is be VBZ cord-022526-j9kg00qf 1887 10 a a DT cord-022526-j9kg00qf 1887 11 confounding confounding JJ cord-022526-j9kg00qf 1887 12 factor factor NN cord-022526-j9kg00qf 1887 13 that that WDT cord-022526-j9kg00qf 1887 14 warrants warrant VBZ cord-022526-j9kg00qf 1887 15 consideration consideration NN cord-022526-j9kg00qf 1887 16 . . . cord-022526-j9kg00qf 1888 1 In in IN cord-022526-j9kg00qf 1888 2 human human JJ cord-022526-j9kg00qf 1888 3 patients patient NNS cord-022526-j9kg00qf 1888 4 , , , cord-022526-j9kg00qf 1888 5 gram gram NN cord-022526-j9kg00qf 1888 6 - - HYPH cord-022526-j9kg00qf 1888 7 negative negative JJ cord-022526-j9kg00qf 1888 8 sepsis sepsis NN cord-022526-j9kg00qf 1888 9 frequently frequently RB cord-022526-j9kg00qf 1888 10 is be VBZ cord-022526-j9kg00qf 1888 11 associated associate VBN cord-022526-j9kg00qf 1888 12 with with IN cord-022526-j9kg00qf 1888 13 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 1888 14 , , , cord-022526-j9kg00qf 1888 15 more more JJR cord-022526-j9kg00qf 1888 16 specifically specifically RB cord-022526-j9kg00qf 1888 17 a a DT cord-022526-j9kg00qf 1888 18 decrease decrease NN cord-022526-j9kg00qf 1888 19 in in IN cord-022526-j9kg00qf 1888 20 serum serum NN cord-022526-j9kg00qf 1888 21 ionized ionized JJ cord-022526-j9kg00qf 1888 22 calcium calcium NN cord-022526-j9kg00qf 1888 23 concentration concentration NN cord-022526-j9kg00qf 1888 24 . . . cord-022526-j9kg00qf 1889 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1889 2 is be VBZ cord-022526-j9kg00qf 1889 3 thought think VBN cord-022526-j9kg00qf 1889 4 to to TO cord-022526-j9kg00qf 1889 5 be be VB cord-022526-j9kg00qf 1889 6 a a DT cord-022526-j9kg00qf 1889 7 causative causative JJ cord-022526-j9kg00qf 1889 8 factor factor NN cord-022526-j9kg00qf 1889 9 , , , cord-022526-j9kg00qf 1889 10 and and CC cord-022526-j9kg00qf 1889 11 proposed propose VBN cord-022526-j9kg00qf 1889 12 mechanisms mechanism NNS cord-022526-j9kg00qf 1889 13 include include VBP cord-022526-j9kg00qf 1889 14 acquired acquire VBN cord-022526-j9kg00qf 1889 15 parathyroid parathyroid JJ cord-022526-j9kg00qf 1889 16 gland gland NN cord-022526-j9kg00qf 1889 17 insufficiency insufficiency NN cord-022526-j9kg00qf 1889 18 , , , cord-022526-j9kg00qf 1889 19 dietary dietary JJ cord-022526-j9kg00qf 1889 20 vitamin vitamin NN cord-022526-j9kg00qf 1889 21 D d NN cord-022526-j9kg00qf 1889 22 deficiency deficiency NN cord-022526-j9kg00qf 1889 23 , , , cord-022526-j9kg00qf 1889 24 impaired impaired JJ cord-022526-j9kg00qf 1889 25 calcium calcium NN cord-022526-j9kg00qf 1889 26 mobilization mobilization NN cord-022526-j9kg00qf 1889 27 , , , cord-022526-j9kg00qf 1889 28 and and CC cord-022526-j9kg00qf 1889 29 renal renal JJ cord-022526-j9kg00qf 1889 30 1α 1α CD cord-022526-j9kg00qf 1889 31 - - HYPH cord-022526-j9kg00qf 1889 32 hydroxylase hydroxylase NN cord-022526-j9kg00qf 1889 33 insufficiency insufficiency NN cord-022526-j9kg00qf 1889 34 leading lead VBG cord-022526-j9kg00qf 1889 35 to to IN cord-022526-j9kg00qf 1889 36 decreased decrease VBN cord-022526-j9kg00qf 1889 37 1,25-hydroxylation 1,25-hydroxylation CD cord-022526-j9kg00qf 1889 38 of of IN cord-022526-j9kg00qf 1889 39 vitamin vitamin NN cord-022526-j9kg00qf 1889 40 D. D. NNP cord-022526-j9kg00qf 1889 41 Hypocalcemia Hypocalcemia NNP cord-022526-j9kg00qf 1889 42 in in IN cord-022526-j9kg00qf 1889 43 septic septic JJ cord-022526-j9kg00qf 1889 44 human human JJ cord-022526-j9kg00qf 1889 45 patients patient NNS cord-022526-j9kg00qf 1889 46 was be VBD cord-022526-j9kg00qf 1889 47 found find VBN cord-022526-j9kg00qf 1889 48 to to TO cord-022526-j9kg00qf 1889 49 be be VB cord-022526-j9kg00qf 1889 50 associated associate VBN cord-022526-j9kg00qf 1889 51 with with IN cord-022526-j9kg00qf 1889 52 hypotension hypotension NN cord-022526-j9kg00qf 1889 53 and and CC cord-022526-j9kg00qf 1889 54 poor poor JJ cord-022526-j9kg00qf 1889 55 outcome outcome NN cord-022526-j9kg00qf 1889 56 . . . cord-022526-j9kg00qf 1890 1 102 102 CD cord-022526-j9kg00qf 1891 1 In in IN cord-022526-j9kg00qf 1891 2 horses horse NNS cord-022526-j9kg00qf 1891 3 with with IN cord-022526-j9kg00qf 1891 4 surgically surgically RB cord-022526-j9kg00qf 1891 5 managed manage VBN cord-022526-j9kg00qf 1891 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1891 7 disease disease NN cord-022526-j9kg00qf 1891 8 , , , cord-022526-j9kg00qf 1891 9 decreased decrease VBD cord-022526-j9kg00qf 1892 1 serum serum NN cord-022526-j9kg00qf 1892 2 ionized ionized JJ cord-022526-j9kg00qf 1892 3 calcium calcium NN cord-022526-j9kg00qf 1892 4 concentration concentration NN cord-022526-j9kg00qf 1892 5 was be VBD cord-022526-j9kg00qf 1892 6 a a DT cord-022526-j9kg00qf 1892 7 common common JJ cord-022526-j9kg00qf 1892 8 finding finding NN cord-022526-j9kg00qf 1892 9 and and CC cord-022526-j9kg00qf 1892 10 was be VBD cord-022526-j9kg00qf 1892 11 most most RBS cord-022526-j9kg00qf 1892 12 severe severe JJ cord-022526-j9kg00qf 1892 13 in in IN cord-022526-j9kg00qf 1892 14 patients patient NNS cord-022526-j9kg00qf 1892 15 with with IN cord-022526-j9kg00qf 1892 16 strangulating strangulating JJ cord-022526-j9kg00qf 1892 17 or or CC cord-022526-j9kg00qf 1892 18 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 1892 19 infarctions infarction NNS cord-022526-j9kg00qf 1892 20 . . . cord-022526-j9kg00qf 1893 1 In in IN cord-022526-j9kg00qf 1893 2 some some DT cord-022526-j9kg00qf 1893 3 horses horse NNS cord-022526-j9kg00qf 1893 4 , , , cord-022526-j9kg00qf 1893 5 ionized ionized JJ cord-022526-j9kg00qf 1893 6 calcium calcium NN cord-022526-j9kg00qf 1893 7 concentration concentration NN cord-022526-j9kg00qf 1893 8 decreased decrease VBD cord-022526-j9kg00qf 1893 9 further further RB cord-022526-j9kg00qf 1893 10 throughout throughout IN cord-022526-j9kg00qf 1893 11 surgery surgery NN cord-022526-j9kg00qf 1893 12 . . . cord-022526-j9kg00qf 1894 1 Treatment treatment NN cord-022526-j9kg00qf 1894 2 with with IN cord-022526-j9kg00qf 1894 3 calcium calcium NN cord-022526-j9kg00qf 1894 4 gluconate gluconate NN cord-022526-j9kg00qf 1894 5 resulted result VBD cord-022526-j9kg00qf 1894 6 in in IN cord-022526-j9kg00qf 1894 7 normalization normalization NN cord-022526-j9kg00qf 1894 8 of of IN cord-022526-j9kg00qf 1894 9 serum serum NN cord-022526-j9kg00qf 1894 10 ionized ionize VBN cord-022526-j9kg00qf 1894 11 calcium calcium NN cord-022526-j9kg00qf 1894 12 concentrations concentration NNS cord-022526-j9kg00qf 1894 13 in in IN cord-022526-j9kg00qf 1894 14 all all DT cord-022526-j9kg00qf 1894 15 cases case NNS cord-022526-j9kg00qf 1894 16 . . . cord-022526-j9kg00qf 1895 1 103 103 CD cord-022526-j9kg00qf 1896 1 Septic septic JJ cord-022526-j9kg00qf 1896 2 neonatal neonatal JJ cord-022526-j9kg00qf 1896 3 patients patient NNS cord-022526-j9kg00qf 1896 4 are be VBP cord-022526-j9kg00qf 1896 5 frequently frequently RB cord-022526-j9kg00qf 1896 6 hypoglycemic hypoglycemic JJ cord-022526-j9kg00qf 1896 7 . . . cord-022526-j9kg00qf 1897 1 Aside aside RB cord-022526-j9kg00qf 1897 2 from from IN cord-022526-j9kg00qf 1897 3 decreased decrease VBD cord-022526-j9kg00qf 1897 4 oral oral JJ cord-022526-j9kg00qf 1897 5 intake intake NN cord-022526-j9kg00qf 1897 6 and and CC cord-022526-j9kg00qf 1897 7 generally generally RB cord-022526-j9kg00qf 1897 8 increased increase VBN cord-022526-j9kg00qf 1897 9 metabolism metabolism NN cord-022526-j9kg00qf 1897 10 , , , cord-022526-j9kg00qf 1897 11 glucose glucose NN cord-022526-j9kg00qf 1897 12 use use NN cord-022526-j9kg00qf 1897 13 by by IN cord-022526-j9kg00qf 1897 14 the the DT cord-022526-j9kg00qf 1897 15 infecting infect VBG cord-022526-j9kg00qf 1897 16 bacteria bacteria NNS cord-022526-j9kg00qf 1897 17 , , , cord-022526-j9kg00qf 1897 18 inhibition inhibition NN cord-022526-j9kg00qf 1897 19 of of IN cord-022526-j9kg00qf 1897 20 gluconeogenesis gluconeogenesis NN cord-022526-j9kg00qf 1897 21 by by IN cord-022526-j9kg00qf 1897 22 endotoxin endotoxin NN cord-022526-j9kg00qf 1897 23 , , , cord-022526-j9kg00qf 1897 24 and and CC cord-022526-j9kg00qf 1897 25 insulinlike insulinlike JJ cord-022526-j9kg00qf 1897 26 activity activity NN cord-022526-j9kg00qf 1897 27 produced produce VBN cord-022526-j9kg00qf 1897 28 by by IN cord-022526-j9kg00qf 1897 29 macrophages macrophage NNS cord-022526-j9kg00qf 1897 30 are be VBP cord-022526-j9kg00qf 1897 31 responsible responsible JJ cord-022526-j9kg00qf 1897 32 for for IN cord-022526-j9kg00qf 1897 33 hypoglycemia hypoglycemia NN cord-022526-j9kg00qf 1897 34 . . . cord-022526-j9kg00qf 1898 1 17 17 CD cord-022526-j9kg00qf 1899 1 Interestingly interestingly RB cord-022526-j9kg00qf 1899 2 , , , cord-022526-j9kg00qf 1899 3 experimental experimental JJ cord-022526-j9kg00qf 1899 4 endotoxin endotoxin NN cord-022526-j9kg00qf 1899 5 administration administration NN cord-022526-j9kg00qf 1899 6 results result NNS cord-022526-j9kg00qf 1899 7 in in IN cord-022526-j9kg00qf 1899 8 transient transient JJ cord-022526-j9kg00qf 1899 9 hyperglycemia hyperglycemia NN cord-022526-j9kg00qf 1899 10 in in IN cord-022526-j9kg00qf 1899 11 adult adult NN cord-022526-j9kg00qf 1899 12 horses horse NNS cord-022526-j9kg00qf 1899 13 , , , cord-022526-j9kg00qf 1899 14 95 95 CD cord-022526-j9kg00qf 1899 15 whereas whereas IN cord-022526-j9kg00qf 1899 16 profound profound JJ cord-022526-j9kg00qf 1899 17 hypoglycemia hypoglycemia NN cord-022526-j9kg00qf 1899 18 occurs occur VBZ cord-022526-j9kg00qf 1899 19 in in IN cord-022526-j9kg00qf 1899 20 foals foal NNS cord-022526-j9kg00qf 1899 21 . . . cord-022526-j9kg00qf 1900 1 104 104 CD cord-022526-j9kg00qf 1901 1 One one PRP cord-022526-j9kg00qf 1901 2 should should MD cord-022526-j9kg00qf 1901 3 evaluate evaluate VB cord-022526-j9kg00qf 1901 4 coagulation coagulation NN cord-022526-j9kg00qf 1901 5 parameters parameter NNS cord-022526-j9kg00qf 1901 6 if if IN cord-022526-j9kg00qf 1901 7 coagulopathy coagulopathy NN cord-022526-j9kg00qf 1901 8 is be VBZ cord-022526-j9kg00qf 1901 9 suspected suspect VBN cord-022526-j9kg00qf 1901 10 . . . cord-022526-j9kg00qf 1902 1 The the DT cord-022526-j9kg00qf 1902 2 most most RBS cord-022526-j9kg00qf 1902 3 significant significant JJ cord-022526-j9kg00qf 1902 4 changes change NNS cord-022526-j9kg00qf 1902 5 can can MD cord-022526-j9kg00qf 1902 6 be be VB cord-022526-j9kg00qf 1902 7 expected expect VBN cord-022526-j9kg00qf 1902 8 with with IN cord-022526-j9kg00qf 1902 9 severe severe JJ cord-022526-j9kg00qf 1902 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 1902 11 disease disease NN cord-022526-j9kg00qf 1902 12 such such JJ cord-022526-j9kg00qf 1902 13 as as IN cord-022526-j9kg00qf 1902 14 colitis colitis NN cord-022526-j9kg00qf 1902 15 , , , cord-022526-j9kg00qf 1902 16 72,73 72,73 CD cord-022526-j9kg00qf 1902 17 devitalized devitalize VBD cord-022526-j9kg00qf 1902 18 intestine intestine NN cord-022526-j9kg00qf 1902 19 as as IN cord-022526-j9kg00qf 1902 20 with with IN cord-022526-j9kg00qf 1902 21 strangulating strangulating JJ cord-022526-j9kg00qf 1902 22 obstruction obstruction NN cord-022526-j9kg00qf 1902 23 , , , cord-022526-j9kg00qf 1902 24 73 73 CD cord-022526-j9kg00qf 1902 25 , , , cord-022526-j9kg00qf 1902 26 105 105 CD cord-022526-j9kg00qf 1902 27 and and CC cord-022526-j9kg00qf 1902 28 with with IN cord-022526-j9kg00qf 1902 29 increased increase VBN cord-022526-j9kg00qf 1902 30 duration duration NN cord-022526-j9kg00qf 1902 31 of of IN cord-022526-j9kg00qf 1902 32 disease disease NN cord-022526-j9kg00qf 1902 33 . . . cord-022526-j9kg00qf 1903 1 In in IN cord-022526-j9kg00qf 1903 2 30 30 CD cord-022526-j9kg00qf 1903 3 horses horse NNS cord-022526-j9kg00qf 1903 4 with with IN cord-022526-j9kg00qf 1903 5 acute acute JJ cord-022526-j9kg00qf 1903 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1903 7 disease disease NN cord-022526-j9kg00qf 1903 8 , , , cord-022526-j9kg00qf 1903 9 coagulation coagulation NN cord-022526-j9kg00qf 1903 10 profiles profile NNS cord-022526-j9kg00qf 1903 11 were be VBD cord-022526-j9kg00qf 1903 12 considered consider VBN cord-022526-j9kg00qf 1903 13 normal normal JJ cord-022526-j9kg00qf 1903 14 in in IN cord-022526-j9kg00qf 1903 15 only only RB cord-022526-j9kg00qf 1903 16 2 2 CD cord-022526-j9kg00qf 1903 17 horses horse NNS cord-022526-j9kg00qf 1903 18 . . . cord-022526-j9kg00qf 1904 1 72 72 CD cord-022526-j9kg00qf 1905 1 Although although IN cord-022526-j9kg00qf 1905 2 coagulation coagulation NN cord-022526-j9kg00qf 1905 3 times time NNS cord-022526-j9kg00qf 1905 4 may may MD cord-022526-j9kg00qf 1905 5 be be VB cord-022526-j9kg00qf 1905 6 shortened shorten VBN cord-022526-j9kg00qf 1905 7 during during IN cord-022526-j9kg00qf 1905 8 the the DT cord-022526-j9kg00qf 1905 9 procoagulant procoagulant JJ cord-022526-j9kg00qf 1905 10 state state NN cord-022526-j9kg00qf 1905 11 , , , cord-022526-j9kg00qf 1905 12 commonly commonly RB cord-022526-j9kg00qf 1905 13 observed observe VBD cord-022526-j9kg00qf 1905 14 abnormalities abnormality NNS cord-022526-j9kg00qf 1905 15 with with IN cord-022526-j9kg00qf 1905 16 developing develop VBG cord-022526-j9kg00qf 1905 17 DIC DIC NNP cord-022526-j9kg00qf 1905 18 include include VBP cord-022526-j9kg00qf 1905 19 an an DT cord-022526-j9kg00qf 1905 20 increased increase VBN cord-022526-j9kg00qf 1905 21 concentration concentration NN cord-022526-j9kg00qf 1905 22 of of IN cord-022526-j9kg00qf 1905 23 FDPs fdp NNS cord-022526-j9kg00qf 1905 24 and and CC cord-022526-j9kg00qf 1905 25 soluble soluble JJ cord-022526-j9kg00qf 1905 26 fibrin fibrin NN cord-022526-j9kg00qf 1905 27 monomer monomer NN cord-022526-j9kg00qf 1905 28 , , , cord-022526-j9kg00qf 1905 29 prolonged prolonged JJ cord-022526-j9kg00qf 1905 30 prothrombin prothrombin NN cord-022526-j9kg00qf 1905 31 time time NN cord-022526-j9kg00qf 1905 32 indicative indicative JJ cord-022526-j9kg00qf 1905 33 of of IN cord-022526-j9kg00qf 1905 34 factor factor NN cord-022526-j9kg00qf 1905 35 VII VII NNP cord-022526-j9kg00qf 1905 36 consumption consumption NN cord-022526-j9kg00qf 1905 37 , , , cord-022526-j9kg00qf 1905 38 prolonged prolong VBN cord-022526-j9kg00qf 1905 39 activated activate VBN cord-022526-j9kg00qf 1905 40 partial partial JJ cord-022526-j9kg00qf 1905 41 thromboplastin thromboplastin NNP cord-022526-j9kg00qf 1905 42 time time NN cord-022526-j9kg00qf 1905 43 indicative indicative JJ cord-022526-j9kg00qf 1905 44 of of IN cord-022526-j9kg00qf 1905 45 factor factor NN cord-022526-j9kg00qf 1905 46 VIII VIII NNP cord-022526-j9kg00qf 1905 47 : : : cord-022526-j9kg00qf 1906 1 C C NNP cord-022526-j9kg00qf 1906 2 and and CC cord-022526-j9kg00qf 1906 3 IX IX NNP cord-022526-j9kg00qf 1906 4 consumption consumption NN cord-022526-j9kg00qf 1906 5 , , , cord-022526-j9kg00qf 1906 6 prolonged prolonged JJ cord-022526-j9kg00qf 1906 7 thrombin thrombin JJ cord-022526-j9kg00qf 1906 8 time time NN cord-022526-j9kg00qf 1906 9 , , , cord-022526-j9kg00qf 1906 10 decreased decrease VBD cord-022526-j9kg00qf 1906 11 AT at IN cord-022526-j9kg00qf 1906 12 III iii CD cord-022526-j9kg00qf 1906 13 activity activity NN cord-022526-j9kg00qf 1906 14 , , , cord-022526-j9kg00qf 1906 15 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 1906 16 , , , cord-022526-j9kg00qf 1906 17 and and CC cord-022526-j9kg00qf 1906 18 decreased decrease VBD cord-022526-j9kg00qf 1906 19 protein protein NN cord-022526-j9kg00qf 1906 20 C c NN cord-022526-j9kg00qf 1906 21 and and CC cord-022526-j9kg00qf 1906 22 plasminogen plasminogen NN cord-022526-j9kg00qf 1906 23 activities activity NNS cord-022526-j9kg00qf 1906 24 . . . cord-022526-j9kg00qf 1907 1 Fibrinogen fibrinogen NN cord-022526-j9kg00qf 1907 2 concentration concentration NN cord-022526-j9kg00qf 1907 3 frequently frequently RB cord-022526-j9kg00qf 1907 4 increases increase VBZ cord-022526-j9kg00qf 1907 5 and and CC cord-022526-j9kg00qf 1907 6 reflects reflect VBZ cord-022526-j9kg00qf 1907 7 the the DT cord-022526-j9kg00qf 1907 8 acute acute JJ cord-022526-j9kg00qf 1907 9 phase phase NN cord-022526-j9kg00qf 1907 10 response response NN cord-022526-j9kg00qf 1907 11 rather rather RB cord-022526-j9kg00qf 1907 12 than than IN cord-022526-j9kg00qf 1907 13 coagulation coagulation NN cord-022526-j9kg00qf 1907 14 abnormalities abnormality NNS cord-022526-j9kg00qf 1907 15 . . . cord-022526-j9kg00qf 1908 1 79 79 CD cord-022526-j9kg00qf 1909 1 Some some DT cord-022526-j9kg00qf 1909 2 clinicians clinician NNS cord-022526-j9kg00qf 1909 3 make make VBP cord-022526-j9kg00qf 1909 4 a a DT cord-022526-j9kg00qf 1909 5 diagnosis diagnosis NN cord-022526-j9kg00qf 1909 6 of of IN cord-022526-j9kg00qf 1909 7 DIC DIC NNP cord-022526-j9kg00qf 1909 8 if if IN cord-022526-j9kg00qf 1909 9 three three CD cord-022526-j9kg00qf 1909 10 or or CC cord-022526-j9kg00qf 1909 11 more more JJR cord-022526-j9kg00qf 1909 12 coagulation coagulation NN cord-022526-j9kg00qf 1909 13 parameters parameter NNS cord-022526-j9kg00qf 1909 14 ( ( -LRB- cord-022526-j9kg00qf 1909 15 specifically specifically RB cord-022526-j9kg00qf 1909 16 AT at IN cord-022526-j9kg00qf 1909 17 III III NNP cord-022526-j9kg00qf 1909 18 , , , cord-022526-j9kg00qf 1909 19 FDPs fdp NNS cord-022526-j9kg00qf 1909 20 , , , cord-022526-j9kg00qf 1909 21 platelet platelet NN cord-022526-j9kg00qf 1909 22 count count NN cord-022526-j9kg00qf 1909 23 , , , cord-022526-j9kg00qf 1909 24 prothrombin prothrombin JJ cord-022526-j9kg00qf 1909 25 time time NN cord-022526-j9kg00qf 1909 26 , , , cord-022526-j9kg00qf 1909 27 and and CC cord-022526-j9kg00qf 1909 28 activated activate VBD cord-022526-j9kg00qf 1909 29 partial partial JJ cord-022526-j9kg00qf 1909 30 thromboplastin thromboplastin NNP cord-022526-j9kg00qf 1909 31 time time NN cord-022526-j9kg00qf 1909 32 ) ) -RRB- cord-022526-j9kg00qf 1909 33 are be VBP cord-022526-j9kg00qf 1909 34 abnormal abnormal JJ cord-022526-j9kg00qf 1909 35 , , , cord-022526-j9kg00qf 1909 36 105 105 CD cord-022526-j9kg00qf 1909 37 whereas whereas IN cord-022526-j9kg00qf 1909 38 others other NNS cord-022526-j9kg00qf 1909 39 require require VBP cord-022526-j9kg00qf 1909 40 overt overt JJ cord-022526-j9kg00qf 1909 41 clinical clinical JJ cord-022526-j9kg00qf 1909 42 signs sign NNS cord-022526-j9kg00qf 1909 43 of of IN cord-022526-j9kg00qf 1909 44 hemorrhage hemorrhage NN cord-022526-j9kg00qf 1909 45 and and CC cord-022526-j9kg00qf 1909 46 concomitant concomitant JJ cord-022526-j9kg00qf 1909 47 thrombosis thrombosis NN cord-022526-j9kg00qf 1909 48 in in IN cord-022526-j9kg00qf 1909 49 addition addition NN cord-022526-j9kg00qf 1909 50 to to IN cord-022526-j9kg00qf 1909 51 classic classic JJ cord-022526-j9kg00qf 1909 52 laboratory laboratory NN cord-022526-j9kg00qf 1909 53 findings finding NNS cord-022526-j9kg00qf 1909 54 . . . cord-022526-j9kg00qf 1910 1 73 73 CD cord-022526-j9kg00qf 1911 1 The the DT cord-022526-j9kg00qf 1911 2 prognostic prognostic JJ cord-022526-j9kg00qf 1911 3 value value NN cord-022526-j9kg00qf 1911 4 of of IN cord-022526-j9kg00qf 1911 5 coagulation coagulation NN cord-022526-j9kg00qf 1911 6 parameters parameter NNS cord-022526-j9kg00qf 1911 7 has have VBZ cord-022526-j9kg00qf 1911 8 been be VBN cord-022526-j9kg00qf 1911 9 evaluated evaluate VBN cord-022526-j9kg00qf 1911 10 . . . cord-022526-j9kg00qf 1912 1 16 16 CD cord-022526-j9kg00qf 1912 2 , , , cord-022526-j9kg00qf 1912 3 73 73 CD cord-022526-j9kg00qf 1912 4 , , , cord-022526-j9kg00qf 1912 5 89 89 CD cord-022526-j9kg00qf 1912 6 Overall Overall NNP cord-022526-j9kg00qf 1912 7 , , , cord-022526-j9kg00qf 1912 8 persistence persistence NN cord-022526-j9kg00qf 1912 9 or or CC cord-022526-j9kg00qf 1912 10 worsening worsening NN cord-022526-j9kg00qf 1912 11 of of IN cord-022526-j9kg00qf 1912 12 abnormalities abnormality NNS cord-022526-j9kg00qf 1912 13 in in IN cord-022526-j9kg00qf 1912 14 the the DT cord-022526-j9kg00qf 1912 15 face face NN cord-022526-j9kg00qf 1912 16 of of IN cord-022526-j9kg00qf 1912 17 treatment treatment NN cord-022526-j9kg00qf 1912 18 appears appear VBZ cord-022526-j9kg00qf 1912 19 to to TO cord-022526-j9kg00qf 1912 20 be be VB cord-022526-j9kg00qf 1912 21 more more RBR cord-022526-j9kg00qf 1912 22 indicative indicative JJ cord-022526-j9kg00qf 1912 23 of of IN cord-022526-j9kg00qf 1912 24 poor poor JJ cord-022526-j9kg00qf 1912 25 outcome outcome NN cord-022526-j9kg00qf 1912 26 than than IN cord-022526-j9kg00qf 1912 27 alterations alteration NNS cord-022526-j9kg00qf 1912 28 in in IN cord-022526-j9kg00qf 1912 29 any any DT cord-022526-j9kg00qf 1912 30 specific specific JJ cord-022526-j9kg00qf 1912 31 parameter parameter NN cord-022526-j9kg00qf 1912 32 . . . cord-022526-j9kg00qf 1913 1 In in IN cord-022526-j9kg00qf 1913 2 one one CD cord-022526-j9kg00qf 1913 3 study study NN cord-022526-j9kg00qf 1913 4 , , , cord-022526-j9kg00qf 1913 5 decreased decrease VBD cord-022526-j9kg00qf 1914 1 serum serum NN cord-022526-j9kg00qf 1914 2 AT at IN cord-022526-j9kg00qf 1914 3 III III NNP cord-022526-j9kg00qf 1914 4 concentration concentration NN cord-022526-j9kg00qf 1914 5 was be VBD cord-022526-j9kg00qf 1914 6 the the DT cord-022526-j9kg00qf 1914 7 parameter parameter NN cord-022526-j9kg00qf 1914 8 most most RBS cord-022526-j9kg00qf 1914 9 commonly commonly RB cord-022526-j9kg00qf 1914 10 associated associate VBN cord-022526-j9kg00qf 1914 11 with with IN cord-022526-j9kg00qf 1914 12 fatal fatal JJ cord-022526-j9kg00qf 1914 13 outcome outcome NN cord-022526-j9kg00qf 1914 14 in in IN cord-022526-j9kg00qf 1914 15 mature mature JJ cord-022526-j9kg00qf 1914 16 horses horse NNS cord-022526-j9kg00qf 1914 17 with with IN cord-022526-j9kg00qf 1914 18 colic colic NN cord-022526-j9kg00qf 1914 19 . . . cord-022526-j9kg00qf 1915 1 72 72 CD cord-022526-j9kg00qf 1916 1 One one PRP cord-022526-j9kg00qf 1916 2 should should MD cord-022526-j9kg00qf 1916 3 further further RB cord-022526-j9kg00qf 1916 4 evaluate evaluate VB cord-022526-j9kg00qf 1916 5 the the DT cord-022526-j9kg00qf 1916 6 serum serum NN cord-022526-j9kg00qf 1916 7 biochemical biochemical JJ cord-022526-j9kg00qf 1916 8 profile profile NN cord-022526-j9kg00qf 1916 9 regarding regard VBG cord-022526-j9kg00qf 1916 10 compromise compromise NN cord-022526-j9kg00qf 1916 11 or or CC cord-022526-j9kg00qf 1916 12 failure failure NN cord-022526-j9kg00qf 1916 13 of of IN cord-022526-j9kg00qf 1916 14 specific specific JJ cord-022526-j9kg00qf 1916 15 organ organ NN cord-022526-j9kg00qf 1916 16 systems system NNS cord-022526-j9kg00qf 1916 17 . . . cord-022526-j9kg00qf 1917 1 Increases increase NNS cord-022526-j9kg00qf 1917 2 in in IN cord-022526-j9kg00qf 1917 3 serum serum NN cord-022526-j9kg00qf 1917 4 creatinine creatinine NN cord-022526-j9kg00qf 1917 5 and and CC cord-022526-j9kg00qf 1917 6 urea urea NN cord-022526-j9kg00qf 1917 7 nitrogen nitrogen NN cord-022526-j9kg00qf 1917 8 concentration concentration NN cord-022526-j9kg00qf 1917 9 can can MD cord-022526-j9kg00qf 1917 10 have have VB cord-022526-j9kg00qf 1917 11 prerenal prerenal JJ cord-022526-j9kg00qf 1917 12 , , , cord-022526-j9kg00qf 1917 13 renal renal JJ cord-022526-j9kg00qf 1917 14 , , , cord-022526-j9kg00qf 1917 15 or or CC cord-022526-j9kg00qf 1917 16 postrenal postrenal JJ cord-022526-j9kg00qf 1917 17 causes cause NNS cord-022526-j9kg00qf 1917 18 . . . cord-022526-j9kg00qf 1918 1 In in IN cord-022526-j9kg00qf 1918 2 cases case NNS cord-022526-j9kg00qf 1918 3 of of IN cord-022526-j9kg00qf 1918 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1918 5 and and CC cord-022526-j9kg00qf 1918 6 sepsis sepsis NN cord-022526-j9kg00qf 1918 7 , , , cord-022526-j9kg00qf 1918 8 prerenal prerenal NNP cord-022526-j9kg00qf 1918 9 azotemia azotemia NNP cord-022526-j9kg00qf 1918 10 caused cause VBN cord-022526-j9kg00qf 1918 11 by by IN cord-022526-j9kg00qf 1918 12 dehydration dehydration NN cord-022526-j9kg00qf 1918 13 and and CC cord-022526-j9kg00qf 1918 14 decreased decrease VBD cord-022526-j9kg00qf 1918 15 renal renal JJ cord-022526-j9kg00qf 1918 16 blood blood NN cord-022526-j9kg00qf 1918 17 flow flow NN cord-022526-j9kg00qf 1918 18 and and CC cord-022526-j9kg00qf 1918 19 renal renal JJ cord-022526-j9kg00qf 1918 20 azotemia azotemia NN cord-022526-j9kg00qf 1918 21 caused cause VBN cord-022526-j9kg00qf 1918 22 by by IN cord-022526-j9kg00qf 1918 23 organ organ NN cord-022526-j9kg00qf 1918 24 failure failure NN cord-022526-j9kg00qf 1918 25 are be VBP cord-022526-j9kg00qf 1918 26 most most RBS cord-022526-j9kg00qf 1918 27 likely likely JJ cord-022526-j9kg00qf 1918 28 to to TO cord-022526-j9kg00qf 1918 29 occur occur VB cord-022526-j9kg00qf 1918 30 . . . cord-022526-j9kg00qf 1919 1 One one PRP cord-022526-j9kg00qf 1919 2 can can MD cord-022526-j9kg00qf 1919 3 use use VB cord-022526-j9kg00qf 1919 4 urine urine NN cord-022526-j9kg00qf 1919 5 specific specific JJ cord-022526-j9kg00qf 1919 6 gravity gravity NN cord-022526-j9kg00qf 1919 7 and and CC cord-022526-j9kg00qf 1919 8 the the DT cord-022526-j9kg00qf 1919 9 response response NN cord-022526-j9kg00qf 1919 10 to to IN cord-022526-j9kg00qf 1919 11 fluid fluid JJ cord-022526-j9kg00qf 1919 12 therapy therapy NN cord-022526-j9kg00qf 1919 13 to to TO cord-022526-j9kg00qf 1919 14 differentiate differentiate VB cord-022526-j9kg00qf 1919 15 renal renal JJ cord-022526-j9kg00qf 1919 16 from from IN cord-022526-j9kg00qf 1919 17 prerenal prerenal JJ cord-022526-j9kg00qf 1919 18 causes cause NNS cord-022526-j9kg00qf 1919 19 of of IN cord-022526-j9kg00qf 1919 20 azotemia azotemia NN cord-022526-j9kg00qf 1919 21 . . . cord-022526-j9kg00qf 1920 1 Although although IN cord-022526-j9kg00qf 1920 2 ideally ideally RB cord-022526-j9kg00qf 1920 3 one one PRP cord-022526-j9kg00qf 1920 4 should should MD cord-022526-j9kg00qf 1920 5 perform perform VB cord-022526-j9kg00qf 1920 6 urinalysis urinalysis NN cord-022526-j9kg00qf 1920 7 before before IN cord-022526-j9kg00qf 1920 8 initiating initiate VBG cord-022526-j9kg00qf 1920 9 fluid fluid JJ cord-022526-j9kg00qf 1920 10 therapy therapy NN cord-022526-j9kg00qf 1920 11 , , , cord-022526-j9kg00qf 1920 12 one one PRP cord-022526-j9kg00qf 1920 13 should should MD cord-022526-j9kg00qf 1920 14 never never RB cord-022526-j9kg00qf 1920 15 delay delay VB cord-022526-j9kg00qf 1920 16 treatment treatment NN cord-022526-j9kg00qf 1920 17 to to TO cord-022526-j9kg00qf 1920 18 obtain obtain VB cord-022526-j9kg00qf 1920 19 a a DT cord-022526-j9kg00qf 1920 20 sample sample NN cord-022526-j9kg00qf 1920 21 and and CC cord-022526-j9kg00qf 1920 22 instead instead RB cord-022526-j9kg00qf 1920 23 should should MD cord-022526-j9kg00qf 1920 24 use use VB cord-022526-j9kg00qf 1920 25 the the DT cord-022526-j9kg00qf 1920 26 first first JJ cord-022526-j9kg00qf 1920 27 available available JJ cord-022526-j9kg00qf 1920 28 urine urine NN cord-022526-j9kg00qf 1920 29 sample sample NN cord-022526-j9kg00qf 1920 30 . . . cord-022526-j9kg00qf 1921 1 With with IN cord-022526-j9kg00qf 1921 2 prerenal prerenal NNP cord-022526-j9kg00qf 1921 3 azotemia azotemia NNP cord-022526-j9kg00qf 1921 4 , , , cord-022526-j9kg00qf 1921 5 urine urine NN cord-022526-j9kg00qf 1921 6 specific specific JJ cord-022526-j9kg00qf 1921 7 gravity gravity NN cord-022526-j9kg00qf 1921 8 is be VBZ cord-022526-j9kg00qf 1921 9 increased increase VBN cord-022526-j9kg00qf 1921 10 , , , cord-022526-j9kg00qf 1921 11 urinalysis urinalysis NN cord-022526-j9kg00qf 1921 12 is be VBZ cord-022526-j9kg00qf 1921 13 normal normal JJ cord-022526-j9kg00qf 1921 14 in in IN cord-022526-j9kg00qf 1921 15 other other JJ cord-022526-j9kg00qf 1921 16 respects respect NNS cord-022526-j9kg00qf 1921 17 , , , cord-022526-j9kg00qf 1921 18 and and CC cord-022526-j9kg00qf 1921 19 azotemia azotemia NN cord-022526-j9kg00qf 1921 20 resolves resolve VBZ cord-022526-j9kg00qf 1921 21 with with IN cord-022526-j9kg00qf 1921 22 adequate adequate JJ cord-022526-j9kg00qf 1921 23 fluid fluid JJ cord-022526-j9kg00qf 1921 24 therapy therapy NN cord-022526-j9kg00qf 1921 25 . . . cord-022526-j9kg00qf 1922 1 Azotemia azotemia NN cord-022526-j9kg00qf 1922 2 in in IN cord-022526-j9kg00qf 1922 3 the the DT cord-022526-j9kg00qf 1922 4 face face NN cord-022526-j9kg00qf 1922 5 of of IN cord-022526-j9kg00qf 1922 6 normal normal JJ cord-022526-j9kg00qf 1922 7 or or CC cord-022526-j9kg00qf 1922 8 decreased decrease VBD cord-022526-j9kg00qf 1922 9 urine urine NN cord-022526-j9kg00qf 1922 10 specific specific JJ cord-022526-j9kg00qf 1922 11 gravity gravity NN cord-022526-j9kg00qf 1922 12 , , , cord-022526-j9kg00qf 1922 13 however however RB cord-022526-j9kg00qf 1922 14 , , , cord-022526-j9kg00qf 1922 15 indicates indicate VBZ cord-022526-j9kg00qf 1922 16 compromised compromise VBN cord-022526-j9kg00qf 1922 17 renal renal JJ cord-022526-j9kg00qf 1922 18 function function NN cord-022526-j9kg00qf 1922 19 . . . cord-022526-j9kg00qf 1923 1 Depending depend VBG cord-022526-j9kg00qf 1923 2 on on IN cord-022526-j9kg00qf 1923 3 the the DT cord-022526-j9kg00qf 1923 4 extent extent NN cord-022526-j9kg00qf 1923 5 of of IN cord-022526-j9kg00qf 1923 6 renal renal JJ cord-022526-j9kg00qf 1923 7 damage damage NN cord-022526-j9kg00qf 1923 8 , , , cord-022526-j9kg00qf 1923 9 proteinuria proteinuria NN cord-022526-j9kg00qf 1923 10 and and CC cord-022526-j9kg00qf 1923 11 hematuria hematuria NN cord-022526-j9kg00qf 1923 12 also also RB cord-022526-j9kg00qf 1923 13 may may MD cord-022526-j9kg00qf 1923 14 be be VB cord-022526-j9kg00qf 1923 15 present present JJ cord-022526-j9kg00qf 1923 16 . . . cord-022526-j9kg00qf 1924 1 Bacteriuria Bacteriuria NNP cord-022526-j9kg00qf 1924 2 and and CC cord-022526-j9kg00qf 1924 3 an an DT cord-022526-j9kg00qf 1924 4 elevated elevated JJ cord-022526-j9kg00qf 1924 5 urine urine NN cord-022526-j9kg00qf 1924 6 leukocyte leukocyte NN cord-022526-j9kg00qf 1924 7 count count NN cord-022526-j9kg00qf 1924 8 may may MD cord-022526-j9kg00qf 1924 9 occur occur VB cord-022526-j9kg00qf 1924 10 if if IN cord-022526-j9kg00qf 1924 11 urinary urinary JJ cord-022526-j9kg00qf 1924 12 tract tract NN cord-022526-j9kg00qf 1924 13 infection infection NN cord-022526-j9kg00qf 1924 14 is be VBZ cord-022526-j9kg00qf 1924 15 the the DT cord-022526-j9kg00qf 1924 16 underlying underlying JJ cord-022526-j9kg00qf 1924 17 cause cause NN cord-022526-j9kg00qf 1924 18 for for IN cord-022526-j9kg00qf 1924 19 the the DT cord-022526-j9kg00qf 1924 20 development development NN cord-022526-j9kg00qf 1924 21 of of IN cord-022526-j9kg00qf 1924 22 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1924 23 . . . cord-022526-j9kg00qf 1925 1 In in IN cord-022526-j9kg00qf 1925 2 these these DT cord-022526-j9kg00qf 1925 3 cases case NNS cord-022526-j9kg00qf 1925 4 , , , cord-022526-j9kg00qf 1925 5 urine urine NN cord-022526-j9kg00qf 1925 6 culture culture NN cord-022526-j9kg00qf 1925 7 and and CC cord-022526-j9kg00qf 1925 8 sensitivity sensitivity NN cord-022526-j9kg00qf 1925 9 testing testing NN cord-022526-j9kg00qf 1925 10 are be VBP cord-022526-j9kg00qf 1925 11 indicated indicate VBN cord-022526-j9kg00qf 1925 12 to to TO cord-022526-j9kg00qf 1925 13 aid aid VB cord-022526-j9kg00qf 1925 14 appropriate appropriate JJ cord-022526-j9kg00qf 1925 15 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1925 16 therapy therapy NN cord-022526-j9kg00qf 1925 17 . . . cord-022526-j9kg00qf 1926 1 Increased increase VBN cord-022526-j9kg00qf 1926 2 serum serum NN cord-022526-j9kg00qf 1926 3 activity activity NN cord-022526-j9kg00qf 1926 4 of of IN cord-022526-j9kg00qf 1926 5 liver liver NN cord-022526-j9kg00qf 1926 6 enzymes enzyme NNS cord-022526-j9kg00qf 1926 7 ( ( -LRB- cord-022526-j9kg00qf 1926 8 aspartate aspartate NN cord-022526-j9kg00qf 1926 9 aminotransferase aminotransferase NN cord-022526-j9kg00qf 1926 10 , , , cord-022526-j9kg00qf 1926 11 γ γ NN cord-022526-j9kg00qf 1926 12 - - HYPH cord-022526-j9kg00qf 1926 13 glutamyltransferase glutamyltransferase NNP cord-022526-j9kg00qf 1926 14 , , , cord-022526-j9kg00qf 1926 15 sorbitol sorbitol NN cord-022526-j9kg00qf 1926 16 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 1926 17 , , , cord-022526-j9kg00qf 1926 18 alkaline alkaline JJ cord-022526-j9kg00qf 1926 19 phosphatase phosphatase NN cord-022526-j9kg00qf 1926 20 ) ) -RRB- cord-022526-j9kg00qf 1926 21 are be VBP cord-022526-j9kg00qf 1926 22 common common JJ cord-022526-j9kg00qf 1926 23 in in IN cord-022526-j9kg00qf 1926 24 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 1926 25 patients patient NNS cord-022526-j9kg00qf 1926 26 ; ; : cord-022526-j9kg00qf 1926 27 however however RB cord-022526-j9kg00qf 1926 28 , , , cord-022526-j9kg00qf 1926 29 liver liver NN cord-022526-j9kg00qf 1926 30 failure failure NN cord-022526-j9kg00qf 1926 31 caused cause VBN cord-022526-j9kg00qf 1926 32 by by IN cord-022526-j9kg00qf 1926 33 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1926 34 is be VBZ cord-022526-j9kg00qf 1926 35 rare rare JJ cord-022526-j9kg00qf 1926 36 . . . cord-022526-j9kg00qf 1927 1 Sorbitol sorbitol NN cord-022526-j9kg00qf 1927 2 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 1927 3 is be VBZ cord-022526-j9kg00qf 1927 4 the the DT cord-022526-j9kg00qf 1927 5 most most RBS cord-022526-j9kg00qf 1927 6 liver liver NN cord-022526-j9kg00qf 1927 7 - - HYPH cord-022526-j9kg00qf 1927 8 specific specific JJ cord-022526-j9kg00qf 1927 9 of of IN cord-022526-j9kg00qf 1927 10 the the DT cord-022526-j9kg00qf 1927 11 enzymes enzyme NNS cord-022526-j9kg00qf 1927 12 and and CC cord-022526-j9kg00qf 1927 13 a a DT cord-022526-j9kg00qf 1927 14 sensitive sensitive JJ cord-022526-j9kg00qf 1927 15 indicator indicator NN cord-022526-j9kg00qf 1927 16 of of IN cord-022526-j9kg00qf 1927 17 acute acute JJ cord-022526-j9kg00qf 1927 18 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 1927 19 necrosis necrosis NN cord-022526-j9kg00qf 1927 20 ; ; : cord-022526-j9kg00qf 1927 21 however however RB cord-022526-j9kg00qf 1927 22 , , , cord-022526-j9kg00qf 1927 23 sorbitol sorbitol NN cord-022526-j9kg00qf 1927 24 is be VBZ cord-022526-j9kg00qf 1928 1 unstable unstable JJ cord-022526-j9kg00qf 1928 2 and and CC cord-022526-j9kg00qf 1928 3 routine routine JJ cord-022526-j9kg00qf 1928 4 assays assay NNS cord-022526-j9kg00qf 1928 5 may may MD cord-022526-j9kg00qf 1928 6 not not RB cord-022526-j9kg00qf 1928 7 be be VB cord-022526-j9kg00qf 1928 8 available available JJ cord-022526-j9kg00qf 1928 9 . . . cord-022526-j9kg00qf 1929 1 One one PRP cord-022526-j9kg00qf 1929 2 should should MD cord-022526-j9kg00qf 1929 3 evaluate evaluate VB cord-022526-j9kg00qf 1929 4 liver liver NN cord-022526-j9kg00qf 1929 5 enzymes enzyme NNS cord-022526-j9kg00qf 1929 6 and and CC cord-022526-j9kg00qf 1929 7 function function NN cord-022526-j9kg00qf 1929 8 tests test NNS cord-022526-j9kg00qf 1929 9 ( ( -LRB- cord-022526-j9kg00qf 1929 10 serum serum NN cord-022526-j9kg00qf 1929 11 indirect indirect JJ cord-022526-j9kg00qf 1929 12 and and CC cord-022526-j9kg00qf 1929 13 direct direct JJ cord-022526-j9kg00qf 1929 14 bilirubin bilirubin NN cord-022526-j9kg00qf 1929 15 concentration concentration NN cord-022526-j9kg00qf 1929 16 , , , cord-022526-j9kg00qf 1929 17 serum serum NN cord-022526-j9kg00qf 1929 18 bile bile NN cord-022526-j9kg00qf 1929 19 acids acid NNS cord-022526-j9kg00qf 1929 20 and and CC cord-022526-j9kg00qf 1929 21 blood blood NN cord-022526-j9kg00qf 1929 22 ammonia ammonia NN cord-022526-j9kg00qf 1929 23 ) ) -RRB- cord-022526-j9kg00qf 1929 24 in in IN cord-022526-j9kg00qf 1929 25 cases case NNS cord-022526-j9kg00qf 1929 26 of of IN cord-022526-j9kg00qf 1929 27 prolonged prolonged JJ cord-022526-j9kg00qf 1929 28 and and CC cord-022526-j9kg00qf 1929 29 profound profound JJ cord-022526-j9kg00qf 1929 30 depression depression NN cord-022526-j9kg00qf 1929 31 to to TO cord-022526-j9kg00qf 1929 32 rule rule VB cord-022526-j9kg00qf 1929 33 out out RP cord-022526-j9kg00qf 1929 34 hepatoencephalopathy hepatoencephalopathy NNP cord-022526-j9kg00qf 1929 35 . . . cord-022526-j9kg00qf 1930 1 One one PRP cord-022526-j9kg00qf 1930 2 should should MD cord-022526-j9kg00qf 1930 3 evaluate evaluate VB cord-022526-j9kg00qf 1930 4 arterial arterial JJ cord-022526-j9kg00qf 1930 5 blood blood NN cord-022526-j9kg00qf 1930 6 gases gas NNS cord-022526-j9kg00qf 1930 7 in in IN cord-022526-j9kg00qf 1930 8 patients patient NNS cord-022526-j9kg00qf 1930 9 with with IN cord-022526-j9kg00qf 1930 10 primary primary JJ cord-022526-j9kg00qf 1930 11 respiratory respiratory JJ cord-022526-j9kg00qf 1930 12 disease disease NN cord-022526-j9kg00qf 1930 13 or or CC cord-022526-j9kg00qf 1930 14 with with IN cord-022526-j9kg00qf 1930 15 clinical clinical JJ cord-022526-j9kg00qf 1930 16 evidence evidence NN cord-022526-j9kg00qf 1930 17 of of IN cord-022526-j9kg00qf 1930 18 respiratory respiratory JJ cord-022526-j9kg00qf 1930 19 failure failure NN cord-022526-j9kg00qf 1930 20 and and CC cord-022526-j9kg00qf 1930 21 in in IN cord-022526-j9kg00qf 1930 22 profoundly profoundly RB cord-022526-j9kg00qf 1930 23 depressed depressed JJ cord-022526-j9kg00qf 1930 24 , , , cord-022526-j9kg00qf 1930 25 recumbent recumbent JJ cord-022526-j9kg00qf 1930 26 patients patient NNS cord-022526-j9kg00qf 1930 27 , , , cord-022526-j9kg00qf 1930 28 especially especially RB cord-022526-j9kg00qf 1930 29 neonates neonate NNS cord-022526-j9kg00qf 1930 30 . . . cord-022526-j9kg00qf 1931 1 Hypoxemia Hypoxemia NNP cord-022526-j9kg00qf 1931 2 observed observe VBD cord-022526-j9kg00qf 1931 3 in in IN cord-022526-j9kg00qf 1931 4 response response NN cord-022526-j9kg00qf 1931 5 to to IN cord-022526-j9kg00qf 1931 6 endotoxin endotoxin NN cord-022526-j9kg00qf 1931 7 infusion infusion NN cord-022526-j9kg00qf 1931 8 is be VBZ cord-022526-j9kg00qf 1931 9 thought think VBN cord-022526-j9kg00qf 1931 10 to to TO cord-022526-j9kg00qf 1931 11 be be VB cord-022526-j9kg00qf 1931 12 caused cause VBN cord-022526-j9kg00qf 1931 13 by by IN cord-022526-j9kg00qf 1931 14 an an DT cord-022526-j9kg00qf 1931 15 increase increase NN cord-022526-j9kg00qf 1931 16 in in IN cord-022526-j9kg00qf 1931 17 ventilation ventilation NN cord-022526-j9kg00qf 1931 18 - - HYPH cord-022526-j9kg00qf 1931 19 perfusion perfusion NN cord-022526-j9kg00qf 1931 20 mismatch mismatch NN cord-022526-j9kg00qf 1931 21 rather rather RB cord-022526-j9kg00qf 1931 22 than than IN cord-022526-j9kg00qf 1931 23 pulmonary pulmonary JJ cord-022526-j9kg00qf 1931 24 edema edema NN cord-022526-j9kg00qf 1931 25 as as IN cord-022526-j9kg00qf 1931 26 occurs occur NNS cord-022526-j9kg00qf 1931 27 in in IN cord-022526-j9kg00qf 1931 28 human human JJ cord-022526-j9kg00qf 1931 29 patients patient NNS cord-022526-j9kg00qf 1931 30 with with IN cord-022526-j9kg00qf 1931 31 acute acute JJ cord-022526-j9kg00qf 1931 32 respiratory respiratory JJ cord-022526-j9kg00qf 1931 33 distress distress NN cord-022526-j9kg00qf 1931 34 syndrome syndrome NN cord-022526-j9kg00qf 1931 35 . . . cord-022526-j9kg00qf 1932 1 The the DT cord-022526-j9kg00qf 1932 2 lung lung NN cord-022526-j9kg00qf 1932 3 is be VBZ cord-022526-j9kg00qf 1932 4 not not RB cord-022526-j9kg00qf 1932 5 a a DT cord-022526-j9kg00qf 1932 6 major major JJ cord-022526-j9kg00qf 1932 7 shock shock NN cord-022526-j9kg00qf 1932 8 organ organ NN cord-022526-j9kg00qf 1932 9 in in IN cord-022526-j9kg00qf 1932 10 horses horse NNS cord-022526-j9kg00qf 1932 11 ; ; : cord-022526-j9kg00qf 1932 12 however however RB cord-022526-j9kg00qf 1932 13 , , , cord-022526-j9kg00qf 1932 14 pulmonary pulmonary JJ cord-022526-j9kg00qf 1932 15 edema edema NN cord-022526-j9kg00qf 1932 16 may may MD cord-022526-j9kg00qf 1932 17 occur occur VB cord-022526-j9kg00qf 1932 18 in in IN cord-022526-j9kg00qf 1932 19 patients patient NNS cord-022526-j9kg00qf 1932 20 with with IN cord-022526-j9kg00qf 1932 21 associated associated JJ cord-022526-j9kg00qf 1932 22 sepsis sepsis NN cord-022526-j9kg00qf 1932 23 or or CC cord-022526-j9kg00qf 1932 24 complications complication NNS cord-022526-j9kg00qf 1932 25 such such JJ cord-022526-j9kg00qf 1932 26 as as IN cord-022526-j9kg00qf 1932 27 DIC DIC NNP cord-022526-j9kg00qf 1932 28 . . . cord-022526-j9kg00qf 1933 1 106 106 CD cord-022526-j9kg00qf 1934 1 The the DT cord-022526-j9kg00qf 1934 2 ideal ideal JJ cord-022526-j9kg00qf 1934 3 treatment treatment NN cord-022526-j9kg00qf 1934 4 for for IN cord-022526-j9kg00qf 1934 5 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1934 6 is be VBZ cord-022526-j9kg00qf 1934 7 prevention prevention NN cord-022526-j9kg00qf 1934 8 . . . cord-022526-j9kg00qf 1935 1 If if IN cord-022526-j9kg00qf 1935 2 one one PRP cord-022526-j9kg00qf 1935 3 possibly possibly RB cord-022526-j9kg00qf 1935 4 can can MD cord-022526-j9kg00qf 1935 5 recognize recognize VB cord-022526-j9kg00qf 1935 6 and and CC cord-022526-j9kg00qf 1935 7 closely closely RB cord-022526-j9kg00qf 1935 8 monitor monitor VB cord-022526-j9kg00qf 1935 9 patients patient NNS cord-022526-j9kg00qf 1935 10 at at IN cord-022526-j9kg00qf 1935 11 risk risk NN cord-022526-j9kg00qf 1935 12 , , , cord-022526-j9kg00qf 1935 13 one one PRP cord-022526-j9kg00qf 1935 14 can can MD cord-022526-j9kg00qf 1935 15 provide provide VB cord-022526-j9kg00qf 1935 16 treatment treatment NN cord-022526-j9kg00qf 1935 17 proactively proactively RB cord-022526-j9kg00qf 1935 18 and and CC cord-022526-j9kg00qf 1935 19 may may MD cord-022526-j9kg00qf 1935 20 reverse reverse VB cord-022526-j9kg00qf 1935 21 the the DT cord-022526-j9kg00qf 1935 22 effects effect NNS cord-022526-j9kg00qf 1935 23 of of IN cord-022526-j9kg00qf 1935 24 endotoxin endotoxin NN cord-022526-j9kg00qf 1935 25 before before IN cord-022526-j9kg00qf 1935 26 the the DT cord-022526-j9kg00qf 1935 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 1935 28 response response NN cord-022526-j9kg00qf 1935 29 has have VBZ cord-022526-j9kg00qf 1935 30 developed develop VBN cord-022526-j9kg00qf 1935 31 a a DT cord-022526-j9kg00qf 1935 32 dynamic dynamic NN cord-022526-j9kg00qf 1935 33 of of IN cord-022526-j9kg00qf 1935 34 its -PRON- PRP$ cord-022526-j9kg00qf 1935 35 own own JJ cord-022526-j9kg00qf 1935 36 . . . cord-022526-j9kg00qf 1936 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 1936 2 , , , cord-022526-j9kg00qf 1936 3 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1936 4 can can MD cord-022526-j9kg00qf 1936 5 develop develop VB cord-022526-j9kg00qf 1936 6 rapidly rapidly RB cord-022526-j9kg00qf 1936 7 , , , cord-022526-j9kg00qf 1936 8 and and CC cord-022526-j9kg00qf 1936 9 horses horse NNS cord-022526-j9kg00qf 1936 10 are be VBP cord-022526-j9kg00qf 1936 11 exquisitely exquisitely RB cord-022526-j9kg00qf 1936 12 sensitive sensitive JJ cord-022526-j9kg00qf 1936 13 to to IN cord-022526-j9kg00qf 1936 14 the the DT cord-022526-j9kg00qf 1936 15 effects effect NNS cord-022526-j9kg00qf 1936 16 of of IN cord-022526-j9kg00qf 1936 17 endotoxin endotoxin NN cord-022526-j9kg00qf 1936 18 ; ; : cord-022526-j9kg00qf 1936 19 therefore therefore RB cord-022526-j9kg00qf 1936 20 , , , cord-022526-j9kg00qf 1936 21 many many JJ cord-022526-j9kg00qf 1936 22 equine equine JJ cord-022526-j9kg00qf 1936 23 patients patient NNS cord-022526-j9kg00qf 1936 24 are be VBP cord-022526-j9kg00qf 1936 25 not not RB cord-022526-j9kg00qf 1936 26 evaluated evaluate VBN cord-022526-j9kg00qf 1936 27 until until IN cord-022526-j9kg00qf 1936 28 reaching reach VBG cord-022526-j9kg00qf 1936 29 more more RBR cord-022526-j9kg00qf 1936 30 severe severe JJ cord-022526-j9kg00qf 1936 31 stages stage NNS cord-022526-j9kg00qf 1936 32 of of IN cord-022526-j9kg00qf 1936 33 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1936 34 or or CC cord-022526-j9kg00qf 1936 35 shock shock NN cord-022526-j9kg00qf 1936 36 . . . cord-022526-j9kg00qf 1937 1 Prognosis prognosis NN cord-022526-j9kg00qf 1937 2 and and CC cord-022526-j9kg00qf 1937 3 patient patient JJ cord-022526-j9kg00qf 1937 4 outcome outcome NN cord-022526-j9kg00qf 1937 5 then then RB cord-022526-j9kg00qf 1937 6 frequently frequently RB cord-022526-j9kg00qf 1937 7 depend depend VBP cord-022526-j9kg00qf 1937 8 on on IN cord-022526-j9kg00qf 1937 9 the the DT cord-022526-j9kg00qf 1937 10 severity severity NN cord-022526-j9kg00qf 1937 11 of of IN cord-022526-j9kg00qf 1937 12 complications complication NNS cord-022526-j9kg00qf 1937 13 associated associate VBN cord-022526-j9kg00qf 1937 14 with with IN cord-022526-j9kg00qf 1937 15 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1937 16 . . . cord-022526-j9kg00qf 1938 1 17 17 CD cord-022526-j9kg00qf 1938 2 Treatment treatment NN cord-022526-j9kg00qf 1938 3 of of IN cord-022526-j9kg00qf 1938 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1938 5 involves involve VBZ cord-022526-j9kg00qf 1938 6 multiple multiple JJ cord-022526-j9kg00qf 1938 7 aspects aspect NNS cord-022526-j9kg00qf 1938 8 , , , cord-022526-j9kg00qf 1938 9 and and CC cord-022526-j9kg00qf 1938 10 the the DT cord-022526-j9kg00qf 1938 11 following follow VBG cord-022526-j9kg00qf 1938 12 strategies strategy NNS cord-022526-j9kg00qf 1938 13 have have VBP cord-022526-j9kg00qf 1938 14 been be VBN cord-022526-j9kg00qf 1938 15 proposed propose VBN cord-022526-j9kg00qf 1938 16 107 107 CD cord-022526-j9kg00qf 1938 17 : : : cord-022526-j9kg00qf 1939 1 • • NNP cord-022526-j9kg00qf 1940 1 Inhibition inhibition NN cord-022526-j9kg00qf 1940 2 of of IN cord-022526-j9kg00qf 1940 3 endotoxin endotoxin NN cord-022526-j9kg00qf 1940 4 release release NN cord-022526-j9kg00qf 1940 5 into into IN cord-022526-j9kg00qf 1940 6 the the DT cord-022526-j9kg00qf 1940 7 circulation circulation NN cord-022526-j9kg00qf 1941 1 • • NNP cord-022526-j9kg00qf 1942 1 Scavenging scavenging NN cord-022526-j9kg00qf 1942 2 of of IN cord-022526-j9kg00qf 1942 3 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1942 4 molecules molecule NNS cord-022526-j9kg00qf 1942 5 to to TO cord-022526-j9kg00qf 1942 6 prevent prevent VB cord-022526-j9kg00qf 1942 7 direct direct JJ cord-022526-j9kg00qf 1942 8 effects effect NNS cord-022526-j9kg00qf 1942 9 and and CC cord-022526-j9kg00qf 1942 10 interaction interaction NN cord-022526-j9kg00qf 1942 11 with with IN cord-022526-j9kg00qf 1942 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 1942 13 cells cell NNS cord-022526-j9kg00qf 1943 1 • • NNP cord-022526-j9kg00qf 1944 1 Inhibition inhibition NN cord-022526-j9kg00qf 1944 2 of of IN cord-022526-j9kg00qf 1944 3 cellular cellular JJ cord-022526-j9kg00qf 1944 4 activation activation NN cord-022526-j9kg00qf 1944 5 by by IN cord-022526-j9kg00qf 1944 6 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1945 1 • • NNP cord-022526-j9kg00qf 1945 2 Inhibition Inhibition NNP cord-022526-j9kg00qf 1945 3 of of IN cord-022526-j9kg00qf 1945 4 mediator mediator NN cord-022526-j9kg00qf 1945 5 synthesis synthesis NN cord-022526-j9kg00qf 1946 1 • • NNP cord-022526-j9kg00qf 1947 1 Interference interference NN cord-022526-j9kg00qf 1947 2 with with IN cord-022526-j9kg00qf 1947 3 the the DT cord-022526-j9kg00qf 1947 4 effects effect NNS cord-022526-j9kg00qf 1947 5 of of IN cord-022526-j9kg00qf 1947 6 inflammatory inflammatory JJ cord-022526-j9kg00qf 1947 7 mediators mediator NNS cord-022526-j9kg00qf 1948 1 • • NNP cord-022526-j9kg00qf 1949 1 General general JJ cord-022526-j9kg00qf 1949 2 supportive supportive JJ cord-022526-j9kg00qf 1949 3 care care NN cord-022526-j9kg00qf 1950 1 In in IN cord-022526-j9kg00qf 1950 2 addition addition NN cord-022526-j9kg00qf 1950 3 , , , cord-022526-j9kg00qf 1950 4 complications complication NNS cord-022526-j9kg00qf 1950 5 such such JJ cord-022526-j9kg00qf 1950 6 as as IN cord-022526-j9kg00qf 1950 7 renal renal JJ cord-022526-j9kg00qf 1950 8 failure failure NN cord-022526-j9kg00qf 1950 9 , , , cord-022526-j9kg00qf 1950 10 one one CD cord-022526-j9kg00qf 1950 11 also also RB cord-022526-j9kg00qf 1950 12 must must MD cord-022526-j9kg00qf 1950 13 address address VB cord-022526-j9kg00qf 1950 14 liver liver NN cord-022526-j9kg00qf 1950 15 failure failure NN cord-022526-j9kg00qf 1950 16 , , , cord-022526-j9kg00qf 1950 17 cardiac cardiac JJ cord-022526-j9kg00qf 1950 18 failure failure NN cord-022526-j9kg00qf 1950 19 , , , cord-022526-j9kg00qf 1950 20 laminitis laminitis NN cord-022526-j9kg00qf 1950 21 , , , cord-022526-j9kg00qf 1950 22 and and CC cord-022526-j9kg00qf 1950 23 abortion abortion NN cord-022526-j9kg00qf 1950 24 in in IN cord-022526-j9kg00qf 1950 25 pregnant pregnant JJ cord-022526-j9kg00qf 1950 26 mares mare NNS cord-022526-j9kg00qf 1950 27 . . . cord-022526-j9kg00qf 1951 1 When when WRB cord-022526-j9kg00qf 1951 2 evaluating evaluate VBG cord-022526-j9kg00qf 1951 3 reports report NNS cord-022526-j9kg00qf 1951 4 concerning concern VBG cord-022526-j9kg00qf 1951 5 the the DT cord-022526-j9kg00qf 1951 6 efficacy efficacy NN cord-022526-j9kg00qf 1951 7 of of IN cord-022526-j9kg00qf 1951 8 any any DT cord-022526-j9kg00qf 1951 9 one one CD cord-022526-j9kg00qf 1951 10 treatment treatment NN cord-022526-j9kg00qf 1951 11 , , , cord-022526-j9kg00qf 1951 12 one one PRP cord-022526-j9kg00qf 1951 13 should should MD cord-022526-j9kg00qf 1951 14 keep keep VB cord-022526-j9kg00qf 1951 15 in in IN cord-022526-j9kg00qf 1951 16 mind mind NN cord-022526-j9kg00qf 1951 17 differences difference NNS cord-022526-j9kg00qf 1951 18 in in IN cord-022526-j9kg00qf 1951 19 underlying underlie VBG cord-022526-j9kg00qf 1951 20 disease disease NN cord-022526-j9kg00qf 1951 21 processes process NNS cord-022526-j9kg00qf 1951 22 and and CC cord-022526-j9kg00qf 1951 23 the the DT cord-022526-j9kg00qf 1951 24 complexity complexity NN cord-022526-j9kg00qf 1951 25 of of IN cord-022526-j9kg00qf 1951 26 the the DT cord-022526-j9kg00qf 1951 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 1951 28 cascade cascade NN cord-022526-j9kg00qf 1951 29 . . . cord-022526-j9kg00qf 1952 1 A a DT cord-022526-j9kg00qf 1952 2 " " `` cord-022526-j9kg00qf 1952 3 one one CD cord-022526-j9kg00qf 1952 4 for for IN cord-022526-j9kg00qf 1952 5 all all DT cord-022526-j9kg00qf 1952 6 " " `` cord-022526-j9kg00qf 1952 7 treatment treatment NN cord-022526-j9kg00qf 1952 8 most most RBS cord-022526-j9kg00qf 1952 9 likely likely RB cord-022526-j9kg00qf 1952 10 will will MD cord-022526-j9kg00qf 1952 11 not not RB cord-022526-j9kg00qf 1952 12 be be VB cord-022526-j9kg00qf 1952 13 found find VBN cord-022526-j9kg00qf 1952 14 , , , cord-022526-j9kg00qf 1952 15 and and CC cord-022526-j9kg00qf 1952 16 similarly similarly RB cord-022526-j9kg00qf 1952 17 , , , cord-022526-j9kg00qf 1952 18 any any DT cord-022526-j9kg00qf 1952 19 one one CD cord-022526-j9kg00qf 1952 20 treatment treatment NN cord-022526-j9kg00qf 1952 21 can can MD cord-022526-j9kg00qf 1952 22 only only RB cord-022526-j9kg00qf 1952 23 address address VB cord-022526-j9kg00qf 1952 24 one one CD cord-022526-j9kg00qf 1952 25 or or CC cord-022526-j9kg00qf 1952 26 few few JJ cord-022526-j9kg00qf 1952 27 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 1952 28 aspects aspect NNS cord-022526-j9kg00qf 1952 29 of of IN cord-022526-j9kg00qf 1952 30 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1952 31 . . . cord-022526-j9kg00qf 1953 1 Understanding understand VBG cord-022526-j9kg00qf 1953 2 the the DT cord-022526-j9kg00qf 1953 3 rationale rationale NN cord-022526-j9kg00qf 1953 4 for for IN cord-022526-j9kg00qf 1953 5 different different JJ cord-022526-j9kg00qf 1953 6 treatment treatment NN cord-022526-j9kg00qf 1953 7 strategies strategy NNS cord-022526-j9kg00qf 1953 8 is be VBZ cord-022526-j9kg00qf 1953 9 important important JJ cord-022526-j9kg00qf 1953 10 to to TO cord-022526-j9kg00qf 1953 11 be be VB cord-022526-j9kg00qf 1953 12 able able JJ cord-022526-j9kg00qf 1953 13 to to TO cord-022526-j9kg00qf 1953 14 tailor tailor VB cord-022526-j9kg00qf 1953 15 treatment treatment NN cord-022526-j9kg00qf 1953 16 to to IN cord-022526-j9kg00qf 1953 17 the the DT cord-022526-j9kg00qf 1953 18 needs need NNS cord-022526-j9kg00qf 1953 19 of of IN cord-022526-j9kg00qf 1953 20 the the DT cord-022526-j9kg00qf 1953 21 patient patient NN cord-022526-j9kg00qf 1953 22 . . . cord-022526-j9kg00qf 1954 1 Inhibition inhibition NN cord-022526-j9kg00qf 1954 2 of of IN cord-022526-j9kg00qf 1954 3 endotoxin endotoxin NN cord-022526-j9kg00qf 1954 4 release release NN cord-022526-j9kg00qf 1954 5 requires require VBZ cord-022526-j9kg00qf 1954 6 identification identification NN cord-022526-j9kg00qf 1954 7 and and CC cord-022526-j9kg00qf 1954 8 removal removal NN cord-022526-j9kg00qf 1954 9 of of IN cord-022526-j9kg00qf 1954 10 its -PRON- PRP$ cord-022526-j9kg00qf 1954 11 source source NN cord-022526-j9kg00qf 1954 12 . . . cord-022526-j9kg00qf 1955 1 Therefore therefore RB cord-022526-j9kg00qf 1955 2 whenever whenever WRB cord-022526-j9kg00qf 1955 3 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1955 4 is be VBZ cord-022526-j9kg00qf 1955 5 evident evident JJ cord-022526-j9kg00qf 1955 6 , , , cord-022526-j9kg00qf 1955 7 the the DT cord-022526-j9kg00qf 1955 8 clinician clinician NN cord-022526-j9kg00qf 1955 9 should should MD cord-022526-j9kg00qf 1955 10 strive strive VB cord-022526-j9kg00qf 1955 11 to to TO cord-022526-j9kg00qf 1955 12 reach reach VB cord-022526-j9kg00qf 1955 13 a a DT cord-022526-j9kg00qf 1955 14 diagnosis diagnosis NN cord-022526-j9kg00qf 1955 15 of of IN cord-022526-j9kg00qf 1955 16 the the DT cord-022526-j9kg00qf 1955 17 underlying underlie VBG cord-022526-j9kg00qf 1955 18 disease disease NN cord-022526-j9kg00qf 1955 19 and and CC cord-022526-j9kg00qf 1955 20 ascertain ascertain VB cord-022526-j9kg00qf 1955 21 whether whether IN cord-022526-j9kg00qf 1955 22 ischemic ischemic JJ cord-022526-j9kg00qf 1955 23 or or CC cord-022526-j9kg00qf 1955 24 inflamed inflamed JJ cord-022526-j9kg00qf 1955 25 bowel bowel NN cord-022526-j9kg00qf 1955 26 or or CC cord-022526-j9kg00qf 1955 27 a a DT cord-022526-j9kg00qf 1955 28 gram gram JJ cord-022526-j9kg00qf 1955 29 - - HYPH cord-022526-j9kg00qf 1955 30 negative negative JJ cord-022526-j9kg00qf 1955 31 septic septic JJ cord-022526-j9kg00qf 1955 32 process process NN cord-022526-j9kg00qf 1955 33 is be VBZ cord-022526-j9kg00qf 1955 34 present present JJ cord-022526-j9kg00qf 1955 35 . . . cord-022526-j9kg00qf 1956 1 Aside aside RB cord-022526-j9kg00qf 1956 2 from from IN cord-022526-j9kg00qf 1956 3 history history NN cord-022526-j9kg00qf 1956 4 , , , cord-022526-j9kg00qf 1956 5 physical physical JJ cord-022526-j9kg00qf 1956 6 examination examination NN cord-022526-j9kg00qf 1956 7 , , , cord-022526-j9kg00qf 1956 8 and and CC cord-022526-j9kg00qf 1956 9 routine routine JJ cord-022526-j9kg00qf 1956 10 laboratory laboratory NN cord-022526-j9kg00qf 1956 11 tests test NNS cord-022526-j9kg00qf 1956 12 , , , cord-022526-j9kg00qf 1956 13 evaluation evaluation NN cord-022526-j9kg00qf 1956 14 may may MD cord-022526-j9kg00qf 1956 15 include include VB cord-022526-j9kg00qf 1956 16 exploratory exploratory JJ cord-022526-j9kg00qf 1956 17 laparotomy laparotomy NN cord-022526-j9kg00qf 1956 18 in in IN cord-022526-j9kg00qf 1956 19 colic colic NN cord-022526-j9kg00qf 1956 20 patients patient NNS cord-022526-j9kg00qf 1956 21 , , , cord-022526-j9kg00qf 1956 22 roentgenologic roentgenologic JJ cord-022526-j9kg00qf 1956 23 and and CC cord-022526-j9kg00qf 1956 24 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 1956 25 evaluation evaluation NN cord-022526-j9kg00qf 1956 26 of of IN cord-022526-j9kg00qf 1956 27 the the DT cord-022526-j9kg00qf 1956 28 pleural pleural JJ cord-022526-j9kg00qf 1956 29 and and CC cord-022526-j9kg00qf 1956 30 peritoneal peritoneal JJ cord-022526-j9kg00qf 1956 31 cavity cavity NN cord-022526-j9kg00qf 1956 32 and and CC cord-022526-j9kg00qf 1956 33 organs organ NNS cord-022526-j9kg00qf 1956 34 , , , cord-022526-j9kg00qf 1956 35 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 1956 36 evaluation evaluation NN cord-022526-j9kg00qf 1956 37 of of IN cord-022526-j9kg00qf 1956 38 umbilical umbilical JJ cord-022526-j9kg00qf 1956 39 remnants remnant NNS cord-022526-j9kg00qf 1956 40 in in IN cord-022526-j9kg00qf 1956 41 neonatal neonatal JJ cord-022526-j9kg00qf 1956 42 foals foal NNS cord-022526-j9kg00qf 1956 43 , , , cord-022526-j9kg00qf 1956 44 evaluation evaluation NN cord-022526-j9kg00qf 1956 45 of of IN cord-022526-j9kg00qf 1956 46 passive passive JJ cord-022526-j9kg00qf 1956 47 transfer transfer NN cord-022526-j9kg00qf 1956 48 and and CC cord-022526-j9kg00qf 1956 49 calculation calculation NN cord-022526-j9kg00qf 1956 50 of of IN cord-022526-j9kg00qf 1956 51 a a DT cord-022526-j9kg00qf 1956 52 sepsis sepsis NN cord-022526-j9kg00qf 1956 53 score score NN cord-022526-j9kg00qf 1956 54 in in IN cord-022526-j9kg00qf 1956 55 foals foal NNS cord-022526-j9kg00qf 1956 56 , , , cord-022526-j9kg00qf 1956 57 and and CC cord-022526-j9kg00qf 1956 58 repeated repeat VBN cord-022526-j9kg00qf 1956 59 culturing culturing NN cord-022526-j9kg00qf 1956 60 of of IN cord-022526-j9kg00qf 1956 61 blood blood NN cord-022526-j9kg00qf 1956 62 or or CC cord-022526-j9kg00qf 1956 63 other other JJ cord-022526-j9kg00qf 1956 64 specimens specimen NNS cord-022526-j9kg00qf 1956 65 . . . cord-022526-j9kg00qf 1957 1 If if IN cord-022526-j9kg00qf 1957 2 one one CD cord-022526-j9kg00qf 1957 3 suspects suspect VBZ cord-022526-j9kg00qf 1957 4 an an DT cord-022526-j9kg00qf 1957 5 infectious infectious JJ cord-022526-j9kg00qf 1957 6 process process NN cord-022526-j9kg00qf 1957 7 , , , cord-022526-j9kg00qf 1957 8 one one PRP cord-022526-j9kg00qf 1957 9 should should MD cord-022526-j9kg00qf 1957 10 pursue pursue VB cord-022526-j9kg00qf 1957 11 identification identification NN cord-022526-j9kg00qf 1957 12 of of IN cord-022526-j9kg00qf 1957 13 the the DT cord-022526-j9kg00qf 1957 14 responsible responsible JJ cord-022526-j9kg00qf 1957 15 microorganisms microorganism NNS cord-022526-j9kg00qf 1957 16 and and CC cord-022526-j9kg00qf 1957 17 their -PRON- PRP$ cord-022526-j9kg00qf 1957 18 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1957 19 sensitivity sensitivity NN cord-022526-j9kg00qf 1957 20 spectrum spectrum NN cord-022526-j9kg00qf 1957 21 ; ; : cord-022526-j9kg00qf 1957 22 however however RB cord-022526-j9kg00qf 1957 23 , , , cord-022526-j9kg00qf 1957 24 one one PRP cord-022526-j9kg00qf 1957 25 should should MD cord-022526-j9kg00qf 1957 26 not not RB cord-022526-j9kg00qf 1957 27 delay delay VB cord-022526-j9kg00qf 1957 28 treatment treatment NN cord-022526-j9kg00qf 1957 29 to to TO cord-022526-j9kg00qf 1957 30 obtain obtain VB cord-022526-j9kg00qf 1957 31 culture culture NN cord-022526-j9kg00qf 1957 32 results result NNS cord-022526-j9kg00qf 1957 33 . . . cord-022526-j9kg00qf 1958 1 Specimen specimen JJ cord-022526-j9kg00qf 1958 2 containers container NNS cord-022526-j9kg00qf 1958 3 with with IN cord-022526-j9kg00qf 1958 4 removal removal NN cord-022526-j9kg00qf 1958 5 devices device NNS cord-022526-j9kg00qf 1958 6 for for IN cord-022526-j9kg00qf 1958 7 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1958 8 are be VBP cord-022526-j9kg00qf 1958 9 available available JJ cord-022526-j9kg00qf 1958 10 and and CC cord-022526-j9kg00qf 1958 11 are be VBP cord-022526-j9kg00qf 1958 12 useful useful JJ cord-022526-j9kg00qf 1958 13 in in IN cord-022526-j9kg00qf 1958 14 cases case NNS cord-022526-j9kg00qf 1958 15 for for IN cord-022526-j9kg00qf 1958 16 which which WDT cord-022526-j9kg00qf 1958 17 one one NN cord-022526-j9kg00qf 1958 18 has have VBZ cord-022526-j9kg00qf 1958 19 initiated initiate VBN cord-022526-j9kg00qf 1958 20 treatment treatment NN cord-022526-j9kg00qf 1958 21 before before IN cord-022526-j9kg00qf 1958 22 specimen specimen NN cord-022526-j9kg00qf 1958 23 collection collection NN cord-022526-j9kg00qf 1958 24 . . . cord-022526-j9kg00qf 1959 1 Once once IN cord-022526-j9kg00qf 1959 2 one one NN cord-022526-j9kg00qf 1959 3 reaches reach VBZ cord-022526-j9kg00qf 1959 4 a a DT cord-022526-j9kg00qf 1959 5 diagnosis diagnosis NN cord-022526-j9kg00qf 1959 6 , , , cord-022526-j9kg00qf 1959 7 one one PRP cord-022526-j9kg00qf 1959 8 must must MD cord-022526-j9kg00qf 1959 9 take take VB cord-022526-j9kg00qf 1959 10 appropriate appropriate JJ cord-022526-j9kg00qf 1959 11 measures measure NNS cord-022526-j9kg00qf 1959 12 to to TO cord-022526-j9kg00qf 1959 13 correct correct VB cord-022526-j9kg00qf 1959 14 the the DT cord-022526-j9kg00qf 1959 15 primary primary JJ cord-022526-j9kg00qf 1959 16 disease disease NN cord-022526-j9kg00qf 1959 17 process process NN cord-022526-j9kg00qf 1959 18 . . . cord-022526-j9kg00qf 1960 1 Examples example NNS cord-022526-j9kg00qf 1960 2 are be VBP cord-022526-j9kg00qf 1960 3 removal removal NN cord-022526-j9kg00qf 1960 4 of of IN cord-022526-j9kg00qf 1960 5 devitalized devitalized JJ cord-022526-j9kg00qf 1960 6 sections section NNS cord-022526-j9kg00qf 1960 7 of of IN cord-022526-j9kg00qf 1960 8 bowel bowel NN cord-022526-j9kg00qf 1960 9 or or CC cord-022526-j9kg00qf 1960 10 infected infected JJ cord-022526-j9kg00qf 1960 11 umbilical umbilical JJ cord-022526-j9kg00qf 1960 12 remnants remnant NNS cord-022526-j9kg00qf 1960 13 , , , cord-022526-j9kg00qf 1960 14 drainage drainage NN cord-022526-j9kg00qf 1960 15 of of IN cord-022526-j9kg00qf 1960 16 infected infected JJ cord-022526-j9kg00qf 1960 17 pleural pleural JJ cord-022526-j9kg00qf 1960 18 or or CC cord-022526-j9kg00qf 1960 19 peritoneal peritoneal JJ cord-022526-j9kg00qf 1960 20 fluid fluid NN cord-022526-j9kg00qf 1960 21 , , , cord-022526-j9kg00qf 1960 22 and and CC cord-022526-j9kg00qf 1960 23 gastric gastric JJ cord-022526-j9kg00qf 1960 24 lavage lavage NN cord-022526-j9kg00qf 1960 25 followed follow VBN cord-022526-j9kg00qf 1960 26 by by IN cord-022526-j9kg00qf 1960 27 administration administration NN cord-022526-j9kg00qf 1960 28 of of IN cord-022526-j9kg00qf 1960 29 mineral mineral NNP cord-022526-j9kg00qf 1960 30 oil oil NN cord-022526-j9kg00qf 1960 31 and/or and/or CC cord-022526-j9kg00qf 1960 32 activated activate VBN cord-022526-j9kg00qf 1960 33 charcoal charcoal NN cord-022526-j9kg00qf 1960 34 in in IN cord-022526-j9kg00qf 1960 35 cases case NNS cord-022526-j9kg00qf 1960 36 of of IN cord-022526-j9kg00qf 1960 37 grain grain NN cord-022526-j9kg00qf 1960 38 overload overload NN cord-022526-j9kg00qf 1960 39 to to TO cord-022526-j9kg00qf 1960 40 prevent prevent VB cord-022526-j9kg00qf 1960 41 further further JJ cord-022526-j9kg00qf 1960 42 absorption absorption NN cord-022526-j9kg00qf 1960 43 of of IN cord-022526-j9kg00qf 1960 44 endotoxin endotoxin NN cord-022526-j9kg00qf 1960 45 . . . cord-022526-j9kg00qf 1961 1 One one PRP cord-022526-j9kg00qf 1961 2 must must MD cord-022526-j9kg00qf 1961 3 address address VB cord-022526-j9kg00qf 1961 4 any any DT cord-022526-j9kg00qf 1961 5 septic septic JJ cord-022526-j9kg00qf 1961 6 process process NN cord-022526-j9kg00qf 1961 7 with with IN cord-022526-j9kg00qf 1961 8 appropriate appropriate JJ cord-022526-j9kg00qf 1961 9 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1961 10 therapy therapy NN cord-022526-j9kg00qf 1961 11 . . . cord-022526-j9kg00qf 1962 1 Initially initially RB cord-022526-j9kg00qf 1962 2 , , , cord-022526-j9kg00qf 1962 3 broad broad JJ cord-022526-j9kg00qf 1962 4 - - HYPH cord-022526-j9kg00qf 1962 5 spectrum spectrum NN cord-022526-j9kg00qf 1962 6 coverage coverage NN cord-022526-j9kg00qf 1962 7 of of IN cord-022526-j9kg00qf 1962 8 the the DT cord-022526-j9kg00qf 1962 9 most most RBS cord-022526-j9kg00qf 1962 10 likely likely JJ cord-022526-j9kg00qf 1962 11 organisms organism NNS cord-022526-j9kg00qf 1962 12 is be VBZ cord-022526-j9kg00qf 1962 13 recommended recommend VBN cord-022526-j9kg00qf 1962 14 ; ; : cord-022526-j9kg00qf 1962 15 one one PRP cord-022526-j9kg00qf 1962 16 then then RB cord-022526-j9kg00qf 1962 17 should should MD cord-022526-j9kg00qf 1962 18 specify specify VB cord-022526-j9kg00qf 1962 19 therapy therapy NN cord-022526-j9kg00qf 1962 20 according accord VBG cord-022526-j9kg00qf 1962 21 to to IN cord-022526-j9kg00qf 1962 22 results result NNS cord-022526-j9kg00qf 1962 23 of of IN cord-022526-j9kg00qf 1962 24 culture culture NN cord-022526-j9kg00qf 1962 25 and and CC cord-022526-j9kg00qf 1962 26 sensitivity sensitivity NN cord-022526-j9kg00qf 1962 27 testing testing NN cord-022526-j9kg00qf 1962 28 . . . cord-022526-j9kg00qf 1963 1 Sepsis sepsis NN cord-022526-j9kg00qf 1963 2 in in IN cord-022526-j9kg00qf 1963 3 foals foal NNS cord-022526-j9kg00qf 1963 4 is be VBZ cord-022526-j9kg00qf 1963 5 caused cause VBN cord-022526-j9kg00qf 1963 6 predominantly predominantly RB cord-022526-j9kg00qf 1963 7 by by IN cord-022526-j9kg00qf 1963 8 gram gram JJ cord-022526-j9kg00qf 1963 9 - - HYPH cord-022526-j9kg00qf 1963 10 negative negative JJ cord-022526-j9kg00qf 1963 11 organisms organism NNS cord-022526-j9kg00qf 1963 12 , , , cord-022526-j9kg00qf 1963 13 of of IN cord-022526-j9kg00qf 1963 14 which which WDT cord-022526-j9kg00qf 1963 15 E. E. NNP cord-022526-j9kg00qf 1963 16 coli coli NNS cord-022526-j9kg00qf 1963 17 , , , cord-022526-j9kg00qf 1963 18 Actinobacillus Actinobacillus NNP cord-022526-j9kg00qf 1963 19 spp spp NNP cord-022526-j9kg00qf 1963 20 . . . cord-022526-j9kg00qf 1964 1 , , , cord-022526-j9kg00qf 1964 2 Klebsiella Klebsiella NNP cord-022526-j9kg00qf 1964 3 spp spp NNS cord-022526-j9kg00qf 1964 4 . . . cord-022526-j9kg00qf 1965 1 , , , cord-022526-j9kg00qf 1965 2 Salmonella Salmonella NNP cord-022526-j9kg00qf 1965 3 spp spp NNS cord-022526-j9kg00qf 1965 4 . . . cord-022526-j9kg00qf 1966 1 and and CC cord-022526-j9kg00qf 1966 2 Pasteurella Pasteurella NNP cord-022526-j9kg00qf 1966 3 spp spp NNS cord-022526-j9kg00qf 1966 4 . . . cord-022526-j9kg00qf 1967 1 frequently frequently RB cord-022526-j9kg00qf 1967 2 are be VBP cord-022526-j9kg00qf 1967 3 identified identify VBN cord-022526-j9kg00qf 1967 4 . . . cord-022526-j9kg00qf 1968 1 108 108 CD cord-022526-j9kg00qf 1969 1 The the DT cord-022526-j9kg00qf 1969 2 reader reader NN cord-022526-j9kg00qf 1969 3 is be VBZ cord-022526-j9kg00qf 1969 4 referred refer VBN cord-022526-j9kg00qf 1969 5 to to IN cord-022526-j9kg00qf 1969 6 other other JJ cord-022526-j9kg00qf 1969 7 texts text NNS cord-022526-j9kg00qf 1969 8 for for IN cord-022526-j9kg00qf 1969 9 review review NN cord-022526-j9kg00qf 1969 10 of of IN cord-022526-j9kg00qf 1969 11 general general JJ cord-022526-j9kg00qf 1969 12 principles principle NNS cord-022526-j9kg00qf 1969 13 of of IN cord-022526-j9kg00qf 1969 14 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1969 15 therapy therapy NN cord-022526-j9kg00qf 1969 16 . . . cord-022526-j9kg00qf 1970 1 Regarding regard VBG cord-022526-j9kg00qf 1970 2 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1970 3 specifically specifically RB cord-022526-j9kg00qf 1970 4 , , , cord-022526-j9kg00qf 1970 5 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1970 6 therapy therapy NN cord-022526-j9kg00qf 1970 7 has have VBZ cord-022526-j9kg00qf 1970 8 been be VBN cord-022526-j9kg00qf 1970 9 suggested suggest VBN cord-022526-j9kg00qf 1970 10 to to TO cord-022526-j9kg00qf 1970 11 increase increase VB cord-022526-j9kg00qf 1970 12 the the DT cord-022526-j9kg00qf 1970 13 amount amount NN cord-022526-j9kg00qf 1970 14 of of IN cord-022526-j9kg00qf 1970 15 circulating circulate VBG cord-022526-j9kg00qf 1970 16 endotoxin endotoxin NN cord-022526-j9kg00qf 1970 17 by by IN cord-022526-j9kg00qf 1970 18 inducing induce VBG cord-022526-j9kg00qf 1970 19 endotoxin endotoxin NN cord-022526-j9kg00qf 1970 20 release release NN cord-022526-j9kg00qf 1970 21 on on IN cord-022526-j9kg00qf 1970 22 cell cell NN cord-022526-j9kg00qf 1970 23 death death NN cord-022526-j9kg00qf 1970 24 of of IN cord-022526-j9kg00qf 1970 25 gram gram NN cord-022526-j9kg00qf 1970 26 - - HYPH cord-022526-j9kg00qf 1970 27 negative negative JJ cord-022526-j9kg00qf 1970 28 bacteria bacteria NNS cord-022526-j9kg00qf 1970 29 . . . cord-022526-j9kg00qf 1971 1 A a DT cord-022526-j9kg00qf 1971 2 recent recent JJ cord-022526-j9kg00qf 1971 3 in in IN cord-022526-j9kg00qf 1971 4 vitro vitro FW cord-022526-j9kg00qf 1971 5 study study NN cord-022526-j9kg00qf 1971 6 compared compare VBN cord-022526-j9kg00qf 1971 7 endotoxin endotoxin NN cord-022526-j9kg00qf 1971 8 release release NN cord-022526-j9kg00qf 1971 9 and and CC cord-022526-j9kg00qf 1971 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 1971 11 mediator mediator NN cord-022526-j9kg00qf 1971 12 activity activity NN cord-022526-j9kg00qf 1971 13 between between IN cord-022526-j9kg00qf 1971 14 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1971 15 commonly commonly RB cord-022526-j9kg00qf 1971 16 used use VBD cord-022526-j9kg00qf 1971 17 to to TO cord-022526-j9kg00qf 1971 18 treat treat VB cord-022526-j9kg00qf 1971 19 E. E. NNP cord-022526-j9kg00qf 1971 20 coli coli NNS cord-022526-j9kg00qf 1971 21 septicemia septicemia NN cord-022526-j9kg00qf 1971 22 in in IN cord-022526-j9kg00qf 1971 23 foals foal NNS cord-022526-j9kg00qf 1971 24 and and CC cord-022526-j9kg00qf 1971 25 specifically specifically RB cord-022526-j9kg00qf 1971 26 evaluated evaluate VBN cord-022526-j9kg00qf 1971 27 amikacin amikacin JJ cord-022526-j9kg00qf 1971 28 , , , cord-022526-j9kg00qf 1971 29 ampicillin ampicillin NN cord-022526-j9kg00qf 1971 30 , , , cord-022526-j9kg00qf 1971 31 amikacin amikacin JJ cord-022526-j9kg00qf 1971 32 plus plus CC cord-022526-j9kg00qf 1971 33 ampicillin ampicillin NN cord-022526-j9kg00qf 1971 34 , , , cord-022526-j9kg00qf 1971 35 ceftiofur ceftiofur JJ cord-022526-j9kg00qf 1971 36 , , , cord-022526-j9kg00qf 1971 37 and and CC cord-022526-j9kg00qf 1971 38 imipenem imipenem NNP cord-022526-j9kg00qf 1971 39 . . . cord-022526-j9kg00qf 1972 1 Although although IN cord-022526-j9kg00qf 1972 2 these these DT cord-022526-j9kg00qf 1972 3 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1972 4 showed show VBD cord-022526-j9kg00qf 1972 5 no no DT cord-022526-j9kg00qf 1972 6 difference difference NN cord-022526-j9kg00qf 1972 7 in in IN cord-022526-j9kg00qf 1972 8 the the DT cord-022526-j9kg00qf 1972 9 ability ability NN cord-022526-j9kg00qf 1972 10 to to TO cord-022526-j9kg00qf 1972 11 kill kill VB cord-022526-j9kg00qf 1972 12 bacteria bacteria NNS cord-022526-j9kg00qf 1972 13 , , , cord-022526-j9kg00qf 1972 14 amikacin amikacin NNS cord-022526-j9kg00qf 1972 15 and and CC cord-022526-j9kg00qf 1972 16 the the DT cord-022526-j9kg00qf 1972 17 amikacin amikacin NN cord-022526-j9kg00qf 1972 18 / / SYM cord-022526-j9kg00qf 1972 19 ampicillin ampicillin JJ cord-022526-j9kg00qf 1972 20 combination combination NN cord-022526-j9kg00qf 1972 21 resulted result VBD cord-022526-j9kg00qf 1972 22 in in IN cord-022526-j9kg00qf 1972 23 the the DT cord-022526-j9kg00qf 1972 24 lowest low JJS cord-022526-j9kg00qf 1972 25 and and CC cord-022526-j9kg00qf 1972 26 ceftiofur ceftiofur JJ cord-022526-j9kg00qf 1972 27 in in IN cord-022526-j9kg00qf 1972 28 the the DT cord-022526-j9kg00qf 1972 29 greatest great JJS cord-022526-j9kg00qf 1972 30 release release NN cord-022526-j9kg00qf 1972 31 of of IN cord-022526-j9kg00qf 1972 32 endotoxin endotoxin NN cord-022526-j9kg00qf 1972 33 . . . cord-022526-j9kg00qf 1973 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1973 2 release release NN cord-022526-j9kg00qf 1973 3 appeared appear VBD cord-022526-j9kg00qf 1973 4 to to TO cord-022526-j9kg00qf 1973 5 be be VB cord-022526-j9kg00qf 1973 6 dose dose NN cord-022526-j9kg00qf 1973 7 - - HYPH cord-022526-j9kg00qf 1973 8 dependent dependent JJ cord-022526-j9kg00qf 1973 9 in in IN cord-022526-j9kg00qf 1973 10 that that DT cord-022526-j9kg00qf 1973 11 lesser less JJR cord-022526-j9kg00qf 1973 12 amounts amount NNS cord-022526-j9kg00qf 1973 13 were be VBD cord-022526-j9kg00qf 1973 14 released release VBN cord-022526-j9kg00qf 1973 15 at at IN cord-022526-j9kg00qf 1973 16 higher high JJR cord-022526-j9kg00qf 1973 17 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1973 18 concentrations concentration NNS cord-022526-j9kg00qf 1973 19 . . . cord-022526-j9kg00qf 1974 1 109 109 CD cord-022526-j9kg00qf 1975 1 Based base VBN cord-022526-j9kg00qf 1975 2 on on IN cord-022526-j9kg00qf 1975 3 these these DT cord-022526-j9kg00qf 1975 4 results result NNS cord-022526-j9kg00qf 1975 5 and and CC cord-022526-j9kg00qf 1975 6 clinical clinical JJ cord-022526-j9kg00qf 1975 7 experience experience NN cord-022526-j9kg00qf 1975 8 , , , cord-022526-j9kg00qf 1975 9 combining combine VBG cord-022526-j9kg00qf 1975 10 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1975 11 therapy therapy NN cord-022526-j9kg00qf 1975 12 with with IN cord-022526-j9kg00qf 1975 13 endotoxin endotoxin NN cord-022526-j9kg00qf 1975 14 - - HYPH cord-022526-j9kg00qf 1975 15 binding bind VBG cord-022526-j9kg00qf 1975 16 agents agent NNS cord-022526-j9kg00qf 1975 17 such such JJ cord-022526-j9kg00qf 1975 18 as as IN cord-022526-j9kg00qf 1975 19 polymyxin polymyxin NN cord-022526-j9kg00qf 1975 20 B B NNP cord-022526-j9kg00qf 1975 21 may may MD cord-022526-j9kg00qf 1975 22 be be VB cord-022526-j9kg00qf 1975 23 beneficial beneficial JJ cord-022526-j9kg00qf 1975 24 , , , cord-022526-j9kg00qf 1975 25 especially especially RB cord-022526-j9kg00qf 1975 26 when when WRB cord-022526-j9kg00qf 1975 27 using use VBG cord-022526-j9kg00qf 1975 28 β β NN cord-022526-j9kg00qf 1975 29 - - HYPH cord-022526-j9kg00qf 1975 30 lactam lactam NN cord-022526-j9kg00qf 1975 31 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1975 32 . . . cord-022526-j9kg00qf 1976 1 Antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1976 2 frequently frequently RB cord-022526-j9kg00qf 1976 3 are be VBP cord-022526-j9kg00qf 1976 4 given give VBN cord-022526-j9kg00qf 1976 5 perioperatively perioperatively NN cord-022526-j9kg00qf 1976 6 to to TO cord-022526-j9kg00qf 1976 7 colic colic VB cord-022526-j9kg00qf 1976 8 patients patient NNS cord-022526-j9kg00qf 1976 9 to to TO cord-022526-j9kg00qf 1976 10 lower lower VB cord-022526-j9kg00qf 1976 11 the the DT cord-022526-j9kg00qf 1976 12 risk risk NN cord-022526-j9kg00qf 1976 13 of of IN cord-022526-j9kg00qf 1976 14 peritonitis peritonitis NN cord-022526-j9kg00qf 1976 15 , , , cord-022526-j9kg00qf 1976 16 incisional incisional JJ cord-022526-j9kg00qf 1976 17 infection infection NN cord-022526-j9kg00qf 1976 18 , , , cord-022526-j9kg00qf 1976 19 and and CC cord-022526-j9kg00qf 1976 20 generalized generalized JJ cord-022526-j9kg00qf 1976 21 sepsis sepsis NN cord-022526-j9kg00qf 1976 22 and and CC cord-022526-j9kg00qf 1976 23 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1976 24 . . . cord-022526-j9kg00qf 1977 1 Because because IN cord-022526-j9kg00qf 1977 2 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1977 3 therapy therapy NN cord-022526-j9kg00qf 1977 4 has have VBZ cord-022526-j9kg00qf 1977 5 been be VBN cord-022526-j9kg00qf 1977 6 implicated implicate VBN cord-022526-j9kg00qf 1977 7 in in IN cord-022526-j9kg00qf 1977 8 the the DT cord-022526-j9kg00qf 1977 9 development development NN cord-022526-j9kg00qf 1977 10 of of IN cord-022526-j9kg00qf 1977 11 colitis colitis NN cord-022526-j9kg00qf 1977 12 , , , cord-022526-j9kg00qf 1977 13 the the DT cord-022526-j9kg00qf 1977 14 duration duration NN cord-022526-j9kg00qf 1977 15 of of IN cord-022526-j9kg00qf 1977 16 treatment treatment NN cord-022526-j9kg00qf 1977 17 should should MD cord-022526-j9kg00qf 1977 18 be be VB cord-022526-j9kg00qf 1977 19 minimal minimal JJ cord-022526-j9kg00qf 1977 20 . . . cord-022526-j9kg00qf 1978 1 Unless unless IN cord-022526-j9kg00qf 1978 2 evidence evidence NN cord-022526-j9kg00qf 1978 3 of of IN cord-022526-j9kg00qf 1978 4 sepsis sepsis NN cord-022526-j9kg00qf 1978 5 , , , cord-022526-j9kg00qf 1978 6 such such JJ cord-022526-j9kg00qf 1978 7 as as IN cord-022526-j9kg00qf 1978 8 fever fever NN cord-022526-j9kg00qf 1978 9 or or CC cord-022526-j9kg00qf 1978 10 changes change NNS cord-022526-j9kg00qf 1978 11 in in IN cord-022526-j9kg00qf 1978 12 the the DT cord-022526-j9kg00qf 1978 13 leukogram leukogram NNP cord-022526-j9kg00qf 1978 14 , , , cord-022526-j9kg00qf 1978 15 is be VBZ cord-022526-j9kg00qf 1978 16 present present JJ cord-022526-j9kg00qf 1978 17 , , , cord-022526-j9kg00qf 1978 18 perioperative perioperative JJ cord-022526-j9kg00qf 1978 19 administration administration NN cord-022526-j9kg00qf 1978 20 of of IN cord-022526-j9kg00qf 1978 21 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 1978 22 should should MD cord-022526-j9kg00qf 1978 23 not not RB cord-022526-j9kg00qf 1978 24 exceed exceed VB cord-022526-j9kg00qf 1978 25 a a DT cord-022526-j9kg00qf 1978 26 24 24 CD cord-022526-j9kg00qf 1978 27 to to TO cord-022526-j9kg00qf 1978 28 48 48 CD cord-022526-j9kg00qf 1978 29 hours hour NNS cord-022526-j9kg00qf 1978 30 . . . cord-022526-j9kg00qf 1979 1 Conversely conversely RB cord-022526-j9kg00qf 1979 2 , , , cord-022526-j9kg00qf 1979 3 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 1979 4 therapy therapy NN cord-022526-j9kg00qf 1979 5 frequently frequently RB cord-022526-j9kg00qf 1979 6 is be VBZ cord-022526-j9kg00qf 1979 7 used use VBN cord-022526-j9kg00qf 1979 8 in in IN cord-022526-j9kg00qf 1979 9 cases case NNS cord-022526-j9kg00qf 1979 10 of of IN cord-022526-j9kg00qf 1979 11 infectious infectious JJ cord-022526-j9kg00qf 1979 12 colitis colitis NN cord-022526-j9kg00qf 1979 13 to to TO cord-022526-j9kg00qf 1979 14 treat treat VB cord-022526-j9kg00qf 1979 15 the the DT cord-022526-j9kg00qf 1979 16 inciting incite VBG cord-022526-j9kg00qf 1979 17 cause cause NN cord-022526-j9kg00qf 1979 18 and and CC cord-022526-j9kg00qf 1979 19 to to TO cord-022526-j9kg00qf 1979 20 prevent prevent VB cord-022526-j9kg00qf 1979 21 sepsis sepsis NN cord-022526-j9kg00qf 1979 22 from from IN cord-022526-j9kg00qf 1979 23 translocation translocation NN cord-022526-j9kg00qf 1979 24 of of IN cord-022526-j9kg00qf 1979 25 bacteria bacteria NNS cord-022526-j9kg00qf 1979 26 . . . cord-022526-j9kg00qf 1980 1 Endotoxin endotoxin NN cord-022526-j9kg00qf 1980 2 typically typically RB cord-022526-j9kg00qf 1980 3 has have VBZ cord-022526-j9kg00qf 1980 4 a a DT cord-022526-j9kg00qf 1980 5 short short JJ cord-022526-j9kg00qf 1980 6 plasma plasma NN cord-022526-j9kg00qf 1980 7 half half JJ cord-022526-j9kg00qf 1980 8 - - HYPH cord-022526-j9kg00qf 1980 9 life life NN cord-022526-j9kg00qf 1980 10 and and CC cord-022526-j9kg00qf 1980 11 is be VBZ cord-022526-j9kg00qf 1980 12 removed remove VBN cord-022526-j9kg00qf 1980 13 rapidly rapidly RB cord-022526-j9kg00qf 1980 14 by by IN cord-022526-j9kg00qf 1980 15 mononuclear mononuclear JJ cord-022526-j9kg00qf 1980 16 phagocytes phagocyte NNS cord-022526-j9kg00qf 1980 17 or or CC cord-022526-j9kg00qf 1980 18 neutralized neutralize VBN cord-022526-j9kg00qf 1980 19 by by IN cord-022526-j9kg00qf 1980 20 binding bind VBG cord-022526-j9kg00qf 1980 21 to to IN cord-022526-j9kg00qf 1980 22 serum serum NN cord-022526-j9kg00qf 1980 23 proteins protein NNS cord-022526-j9kg00qf 1980 24 and and CC cord-022526-j9kg00qf 1980 25 lipoproteins lipoprotein NNS cord-022526-j9kg00qf 1980 26 . . . cord-022526-j9kg00qf 1981 1 Many many JJ cord-022526-j9kg00qf 1981 2 conditions condition NNS cord-022526-j9kg00qf 1981 3 responsible responsible JJ cord-022526-j9kg00qf 1981 4 for for IN cord-022526-j9kg00qf 1981 5 the the DT cord-022526-j9kg00qf 1981 6 development development NN cord-022526-j9kg00qf 1981 7 of of IN cord-022526-j9kg00qf 1981 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1981 9 in in IN cord-022526-j9kg00qf 1981 10 horses horse NNS cord-022526-j9kg00qf 1981 11 , , , cord-022526-j9kg00qf 1981 12 however however RB cord-022526-j9kg00qf 1981 13 , , , cord-022526-j9kg00qf 1981 14 are be VBP cord-022526-j9kg00qf 1981 15 associated associate VBN cord-022526-j9kg00qf 1981 16 with with IN cord-022526-j9kg00qf 1981 17 an an DT cord-022526-j9kg00qf 1981 18 ongoing ongoing JJ cord-022526-j9kg00qf 1981 19 release release NN cord-022526-j9kg00qf 1981 20 of of IN cord-022526-j9kg00qf 1981 21 endotoxin endotoxin NN cord-022526-j9kg00qf 1981 22 . . . cord-022526-j9kg00qf 1982 1 Examples example NNS cord-022526-j9kg00qf 1982 2 include include VBP cord-022526-j9kg00qf 1982 3 severe severe JJ cord-022526-j9kg00qf 1982 4 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1982 5 inflammation inflammation NN cord-022526-j9kg00qf 1982 6 as as IN cord-022526-j9kg00qf 1982 7 in in IN cord-022526-j9kg00qf 1982 8 proximal proximal JJ cord-022526-j9kg00qf 1982 9 enteritis enteritis NN cord-022526-j9kg00qf 1982 10 or or CC cord-022526-j9kg00qf 1982 11 colitis colitis NN cord-022526-j9kg00qf 1982 12 , , , cord-022526-j9kg00qf 1982 13 grain grain NN cord-022526-j9kg00qf 1982 14 overload overload NN cord-022526-j9kg00qf 1982 15 , , , cord-022526-j9kg00qf 1982 16 or or CC cord-022526-j9kg00qf 1982 17 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 1982 18 sepsis sepsis NN cord-022526-j9kg00qf 1982 19 . . . cord-022526-j9kg00qf 1983 1 Therapy therapy NN cord-022526-j9kg00qf 1983 2 directed direct VBN cord-022526-j9kg00qf 1983 3 against against IN cord-022526-j9kg00qf 1983 4 endotoxin endotoxin NN cord-022526-j9kg00qf 1983 5 itself -PRON- PRP cord-022526-j9kg00qf 1983 6 may may MD cord-022526-j9kg00qf 1983 7 be be VB cord-022526-j9kg00qf 1983 8 able able JJ cord-022526-j9kg00qf 1983 9 to to TO cord-022526-j9kg00qf 1983 10 interrupt interrupt VB cord-022526-j9kg00qf 1983 11 the the DT cord-022526-j9kg00qf 1983 12 continuous continuous JJ cord-022526-j9kg00qf 1983 13 activation activation NN cord-022526-j9kg00qf 1983 14 of of IN cord-022526-j9kg00qf 1983 15 the the DT cord-022526-j9kg00qf 1983 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 1983 17 cascade cascade NN cord-022526-j9kg00qf 1983 18 in in IN cord-022526-j9kg00qf 1983 19 these these DT cord-022526-j9kg00qf 1983 20 cases case NNS cord-022526-j9kg00qf 1983 21 . . . cord-022526-j9kg00qf 1984 1 Further further JJ cord-022526-j9kg00qf 1984 2 benefits benefit NNS cord-022526-j9kg00qf 1984 3 of of IN cord-022526-j9kg00qf 1984 4 antiendotoxin antiendotoxin NN cord-022526-j9kg00qf 1984 5 treatment treatment NN cord-022526-j9kg00qf 1984 6 may may MD cord-022526-j9kg00qf 1984 7 be be VB cord-022526-j9kg00qf 1984 8 derived derive VBN cord-022526-j9kg00qf 1984 9 if if IN cord-022526-j9kg00qf 1984 10 large large JJ cord-022526-j9kg00qf 1984 11 amounts amount NNS cord-022526-j9kg00qf 1984 12 of of IN cord-022526-j9kg00qf 1984 13 endotoxin endotoxin NN cord-022526-j9kg00qf 1984 14 have have VBP cord-022526-j9kg00qf 1984 15 been be VBN cord-022526-j9kg00qf 1984 16 released release VBN cord-022526-j9kg00qf 1984 17 before before IN cord-022526-j9kg00qf 1984 18 the the DT cord-022526-j9kg00qf 1984 19 inciting incite VBG cord-022526-j9kg00qf 1984 20 cause cause NN cord-022526-j9kg00qf 1984 21 can can MD cord-022526-j9kg00qf 1984 22 be be VB cord-022526-j9kg00qf 1984 23 addressed address VBN cord-022526-j9kg00qf 1984 24 . . . cord-022526-j9kg00qf 1985 1 An an DT cord-022526-j9kg00qf 1985 2 important important JJ cord-022526-j9kg00qf 1985 3 consideration consideration NN cord-022526-j9kg00qf 1985 4 regarding regard VBG cord-022526-j9kg00qf 1985 5 the the DT cord-022526-j9kg00qf 1985 6 efficacy efficacy NN cord-022526-j9kg00qf 1985 7 of of IN cord-022526-j9kg00qf 1985 8 immunotherapy immunotherapy NN cord-022526-j9kg00qf 1985 9 is be VBZ cord-022526-j9kg00qf 1985 10 the the DT cord-022526-j9kg00qf 1985 11 region region NN cord-022526-j9kg00qf 1985 12 of of IN cord-022526-j9kg00qf 1985 13 the the DT cord-022526-j9kg00qf 1985 14 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1985 15 molecule molecule NN cord-022526-j9kg00qf 1985 16 against against IN cord-022526-j9kg00qf 1985 17 which which WDT cord-022526-j9kg00qf 1985 18 antibodies antibody NNS cord-022526-j9kg00qf 1985 19 are be VBP cord-022526-j9kg00qf 1985 20 raised raise VBN cord-022526-j9kg00qf 1985 21 . . . cord-022526-j9kg00qf 1986 1 The the DT cord-022526-j9kg00qf 1986 2 O o NN cord-022526-j9kg00qf 1986 3 - - HYPH cord-022526-j9kg00qf 1986 4 chain chain NN cord-022526-j9kg00qf 1986 5 of of IN cord-022526-j9kg00qf 1986 6 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1986 7 acts act NNS cord-022526-j9kg00qf 1986 8 as as IN cord-022526-j9kg00qf 1986 9 a a DT cord-022526-j9kg00qf 1986 10 potent potent JJ cord-022526-j9kg00qf 1986 11 antigen antigen NN cord-022526-j9kg00qf 1986 12 on on IN cord-022526-j9kg00qf 1986 13 infection infection NN cord-022526-j9kg00qf 1986 14 with with IN cord-022526-j9kg00qf 1986 15 gram gram JJ cord-022526-j9kg00qf 1986 16 - - HYPH cord-022526-j9kg00qf 1986 17 negative negative JJ cord-022526-j9kg00qf 1986 18 bacteria bacteria NNS cord-022526-j9kg00qf 1986 19 6 6 CD cord-022526-j9kg00qf 1986 20 ; ; : cord-022526-j9kg00qf 1986 21 however however RB cord-022526-j9kg00qf 1986 22 , , , cord-022526-j9kg00qf 1986 23 antibodies antibody NNS cord-022526-j9kg00qf 1986 24 directed direct VBN cord-022526-j9kg00qf 1986 25 against against IN cord-022526-j9kg00qf 1986 26 the the DT cord-022526-j9kg00qf 1986 27 O o NN cord-022526-j9kg00qf 1986 28 - - HYPH cord-022526-j9kg00qf 1986 29 chain chain NN cord-022526-j9kg00qf 1986 30 are be VBP cord-022526-j9kg00qf 1986 31 serotype serotype NN cord-022526-j9kg00qf 1986 32 specific specific JJ cord-022526-j9kg00qf 1986 33 and and CC cord-022526-j9kg00qf 1986 34 can can MD cord-022526-j9kg00qf 1986 35 not not RB cord-022526-j9kg00qf 1986 36 afford afford VB cord-022526-j9kg00qf 1986 37 significant significant JJ cord-022526-j9kg00qf 1986 38 cross cross NN cord-022526-j9kg00qf 1986 39 - - NN cord-022526-j9kg00qf 1986 40 protection protection NN cord-022526-j9kg00qf 1986 41 against against IN cord-022526-j9kg00qf 1986 42 heterologous heterologous JJ cord-022526-j9kg00qf 1986 43 bacterial bacterial JJ cord-022526-j9kg00qf 1986 44 strains strain NNS cord-022526-j9kg00qf 1986 45 . . . cord-022526-j9kg00qf 1987 1 The the DT cord-022526-j9kg00qf 1987 2 core core NN cord-022526-j9kg00qf 1987 3 and and CC cord-022526-j9kg00qf 1987 4 lipid lipid NN cord-022526-j9kg00qf 1987 5 A a DT cord-022526-j9kg00qf 1987 6 region region NN cord-022526-j9kg00qf 1987 7 , , , cord-022526-j9kg00qf 1987 8 both both DT cord-022526-j9kg00qf 1987 9 of of IN cord-022526-j9kg00qf 1987 10 which which WDT cord-022526-j9kg00qf 1987 11 show show VBP cord-022526-j9kg00qf 1987 12 a a DT cord-022526-j9kg00qf 1987 13 much much RB cord-022526-j9kg00qf 1987 14 higher high JJR cord-022526-j9kg00qf 1987 15 degree degree NN cord-022526-j9kg00qf 1987 16 of of IN cord-022526-j9kg00qf 1987 17 homology homology NN cord-022526-j9kg00qf 1987 18 between between IN cord-022526-j9kg00qf 1987 19 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1987 20 derived derive VBN cord-022526-j9kg00qf 1987 21 from from IN cord-022526-j9kg00qf 1987 22 different different JJ cord-022526-j9kg00qf 1987 23 bacterial bacterial JJ cord-022526-j9kg00qf 1987 24 strains strain NNS cord-022526-j9kg00qf 1987 25 , , , cord-022526-j9kg00qf 1987 26 offer offer VBP cord-022526-j9kg00qf 1987 27 a a DT cord-022526-j9kg00qf 1987 28 more more RBR cord-022526-j9kg00qf 1987 29 promising promising JJ cord-022526-j9kg00qf 1987 30 target target NN cord-022526-j9kg00qf 1987 31 for for IN cord-022526-j9kg00qf 1987 32 immunotherapy immunotherapy NN cord-022526-j9kg00qf 1987 33 . . . cord-022526-j9kg00qf 1988 1 Active active JJ cord-022526-j9kg00qf 1988 2 immunization immunization NN cord-022526-j9kg00qf 1988 3 against against IN cord-022526-j9kg00qf 1988 4 endotoxin endotoxin NN cord-022526-j9kg00qf 1988 5 has have VBZ cord-022526-j9kg00qf 1988 6 been be VBN cord-022526-j9kg00qf 1988 7 reported report VBN cord-022526-j9kg00qf 1988 8 for for IN cord-022526-j9kg00qf 1988 9 horses horse NNS cord-022526-j9kg00qf 1988 10 . . . cord-022526-j9kg00qf 1989 1 Vaccination vaccination NN cord-022526-j9kg00qf 1989 2 with with IN cord-022526-j9kg00qf 1989 3 a a DT cord-022526-j9kg00qf 1989 4 bacterin/ bacterin/ CD cord-022526-j9kg00qf 1989 5 toxoid toxoid NN cord-022526-j9kg00qf 1989 6 vaccine vaccine NN cord-022526-j9kg00qf 1989 7 prepared prepare VBN cord-022526-j9kg00qf 1989 8 from from IN cord-022526-j9kg00qf 1989 9 rough rough JJ cord-022526-j9kg00qf 1989 10 mutants mutant NNS cord-022526-j9kg00qf 1989 11 of of IN cord-022526-j9kg00qf 1989 12 Salmonella Salmonella NNP cord-022526-j9kg00qf 1989 13 typhimurium typhimurium NN cord-022526-j9kg00qf 1989 14 or or CC cord-022526-j9kg00qf 1990 1 S. S. NNP cord-022526-j9kg00qf 1990 2 enteritidis enteritidis NN cord-022526-j9kg00qf 1990 3 protected protect VBD cord-022526-j9kg00qf 1990 4 horses horse NNS cord-022526-j9kg00qf 1990 5 against against IN cord-022526-j9kg00qf 1990 6 homologous homologous JJ cord-022526-j9kg00qf 1990 7 and and CC cord-022526-j9kg00qf 1990 8 heterologous heterologous JJ cord-022526-j9kg00qf 1990 9 endotoxin endotoxin NN cord-022526-j9kg00qf 1990 10 challenge challenge NN cord-022526-j9kg00qf 1990 11 110 110 CD cord-022526-j9kg00qf 1990 12 , , , cord-022526-j9kg00qf 1990 13 111 111 CD cord-022526-j9kg00qf 1990 14 and and CC cord-022526-j9kg00qf 1990 15 carbohydrate carbohydrate NN cord-022526-j9kg00qf 1990 16 overload overload NN cord-022526-j9kg00qf 1990 17 . . . cord-022526-j9kg00qf 1991 1 111 111 CD cord-022526-j9kg00qf 1992 1 Despite despite IN cord-022526-j9kg00qf 1992 2 these these DT cord-022526-j9kg00qf 1992 3 encouraging encourage VBG cord-022526-j9kg00qf 1992 4 results result NNS cord-022526-j9kg00qf 1992 5 and and CC cord-022526-j9kg00qf 1992 6 the the DT cord-022526-j9kg00qf 1992 7 current current JJ cord-022526-j9kg00qf 1992 8 availability availability NN cord-022526-j9kg00qf 1992 9 of of IN cord-022526-j9kg00qf 1992 10 a a DT cord-022526-j9kg00qf 1992 11 vaccine vaccine NN cord-022526-j9kg00qf 1992 12 for for IN cord-022526-j9kg00qf 1992 13 use use NN cord-022526-j9kg00qf 1992 14 in in IN cord-022526-j9kg00qf 1992 15 horses horse NNS cord-022526-j9kg00qf 1992 16 ( ( -LRB- cord-022526-j9kg00qf 1992 17 Endovac Endovac NNP cord-022526-j9kg00qf 1992 18 - - HYPH cord-022526-j9kg00qf 1992 19 Equi Equi NNP cord-022526-j9kg00qf 1992 20 , , , cord-022526-j9kg00qf 1992 21 Immvac Immvac NNP cord-022526-j9kg00qf 1992 22 Inc. Inc. NNP cord-022526-j9kg00qf 1992 23 , , , cord-022526-j9kg00qf 1992 24 Columbus Columbus NNP cord-022526-j9kg00qf 1992 25 , , , cord-022526-j9kg00qf 1992 26 Missouri Missouri NNP cord-022526-j9kg00qf 1992 27 ) ) -RRB- cord-022526-j9kg00qf 1992 28 , , , cord-022526-j9kg00qf 1992 29 active active JJ cord-022526-j9kg00qf 1992 30 immunization immunization NN cord-022526-j9kg00qf 1992 31 against against IN cord-022526-j9kg00qf 1992 32 endotoxin endotoxin NN cord-022526-j9kg00qf 1992 33 does do VBZ cord-022526-j9kg00qf 1992 34 not not RB cord-022526-j9kg00qf 1992 35 appear appear VB cord-022526-j9kg00qf 1992 36 to to TO cord-022526-j9kg00qf 1992 37 be be VB cord-022526-j9kg00qf 1992 38 a a DT cord-022526-j9kg00qf 1992 39 common common JJ cord-022526-j9kg00qf 1992 40 practice practice NN cord-022526-j9kg00qf 1992 41 . . . cord-022526-j9kg00qf 1993 1 In in IN cord-022526-j9kg00qf 1993 2 comparison comparison NN cord-022526-j9kg00qf 1993 3 , , , cord-022526-j9kg00qf 1993 4 passive passive JJ cord-022526-j9kg00qf 1993 5 immunization immunization NN cord-022526-j9kg00qf 1993 6 with with IN cord-022526-j9kg00qf 1993 7 antilipopolysaccharide antilipopolysaccharide NNP cord-022526-j9kg00qf 1993 8 antibodies antibody NNS cord-022526-j9kg00qf 1993 9 is be VBZ cord-022526-j9kg00qf 1993 10 used use VBN cord-022526-j9kg00qf 1993 11 widely widely RB cord-022526-j9kg00qf 1993 12 . . . cord-022526-j9kg00qf 1994 1 Rough rough JJ cord-022526-j9kg00qf 1994 2 bacterial bacterial JJ cord-022526-j9kg00qf 1994 3 mutants mutant NNS cord-022526-j9kg00qf 1994 4 , , , cord-022526-j9kg00qf 1994 5 most most RBS cord-022526-j9kg00qf 1994 6 commonly commonly RB cord-022526-j9kg00qf 1994 7 J5 J5 NNP cord-022526-j9kg00qf 1994 8 of of IN cord-022526-j9kg00qf 1994 9 E. E. NNP cord-022526-j9kg00qf 1994 10 coli coli NNS cord-022526-j9kg00qf 1994 11 O111 o111 CD cord-022526-j9kg00qf 1994 12 : : : cord-022526-j9kg00qf 1995 1 B4 B4 NNP cord-022526-j9kg00qf 1995 2 and and CC cord-022526-j9kg00qf 1995 3 S. S. NNP cord-022526-j9kg00qf 1995 4 minnesota minnesota NNP cord-022526-j9kg00qf 1995 5 Re595 Re595 NNP cord-022526-j9kg00qf 1995 6 , , , cord-022526-j9kg00qf 1995 7 are be VBP cord-022526-j9kg00qf 1995 8 used use VBN cord-022526-j9kg00qf 1995 9 to to TO cord-022526-j9kg00qf 1995 10 immunize immunize VB cord-022526-j9kg00qf 1995 11 donor donor NN cord-022526-j9kg00qf 1995 12 horses horse NNS cord-022526-j9kg00qf 1995 13 and and CC cord-022526-j9kg00qf 1995 14 subsequently subsequently RB cord-022526-j9kg00qf 1995 15 prepare prepare VBP cord-022526-j9kg00qf 1995 16 serum serum NN cord-022526-j9kg00qf 1995 17 or or CC cord-022526-j9kg00qf 1995 18 plasma plasma NN cord-022526-j9kg00qf 1995 19 products product NNS cord-022526-j9kg00qf 1995 20 . . . cord-022526-j9kg00qf 1996 1 Proposed propose VBN cord-022526-j9kg00qf 1996 2 mechanisms mechanism NNS cord-022526-j9kg00qf 1996 3 of of IN cord-022526-j9kg00qf 1996 4 action action NN cord-022526-j9kg00qf 1996 5 after after IN cord-022526-j9kg00qf 1996 6 binding bind VBG cord-022526-j9kg00qf 1996 7 of of IN cord-022526-j9kg00qf 1996 8 the the DT cord-022526-j9kg00qf 1996 9 antibodies antibody NNS cord-022526-j9kg00qf 1996 10 to to IN cord-022526-j9kg00qf 1996 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 1996 12 include include VBP cord-022526-j9kg00qf 1996 13 steric steric JJ cord-022526-j9kg00qf 1996 14 blockade blockade NN cord-022526-j9kg00qf 1996 15 of of IN cord-022526-j9kg00qf 1996 16 lipid lipid NN cord-022526-j9kg00qf 1996 17 A a DT cord-022526-j9kg00qf 1996 18 interaction interaction NN cord-022526-j9kg00qf 1996 19 with with IN cord-022526-j9kg00qf 1996 20 cellular cellular JJ cord-022526-j9kg00qf 1996 21 receptors receptor NNS cord-022526-j9kg00qf 1996 22 and and CC cord-022526-j9kg00qf 1996 23 enhanced enhance VBN cord-022526-j9kg00qf 1996 24 bacterial bacterial JJ cord-022526-j9kg00qf 1996 25 clearance clearance NN cord-022526-j9kg00qf 1996 26 by by IN cord-022526-j9kg00qf 1996 27 opsonization opsonization NN cord-022526-j9kg00qf 1996 28 . . . cord-022526-j9kg00qf 1997 1 [ [ -LRB- cord-022526-j9kg00qf 1997 2 112 112 CD cord-022526-j9kg00qf 1997 3 ] ] -RRB- cord-022526-j9kg00qf 1997 4 [ [ -LRB- cord-022526-j9kg00qf 1997 5 113 113 CD cord-022526-j9kg00qf 1997 6 ] ] -RRB- cord-022526-j9kg00qf 1997 7 [ [ -LRB- cord-022526-j9kg00qf 1997 8 114 114 CD cord-022526-j9kg00qf 1997 9 ] ] -RRB- cord-022526-j9kg00qf 1998 1 Studies study NNS cord-022526-j9kg00qf 1998 2 concerning concern VBG cord-022526-j9kg00qf 1998 3 the the DT cord-022526-j9kg00qf 1998 4 efficacy efficacy NN cord-022526-j9kg00qf 1998 5 of of IN cord-022526-j9kg00qf 1998 6 antibody antibody NNP cord-022526-j9kg00qf 1998 7 administration administration NN cord-022526-j9kg00qf 1998 8 in in IN cord-022526-j9kg00qf 1998 9 equine equine JJ cord-022526-j9kg00qf 1998 10 patients patient NNS cord-022526-j9kg00qf 1998 11 vary vary VBP cord-022526-j9kg00qf 1998 12 in in IN cord-022526-j9kg00qf 1998 13 their -PRON- PRP$ cord-022526-j9kg00qf 1998 14 results result NNS cord-022526-j9kg00qf 1998 15 . . . cord-022526-j9kg00qf 1999 1 Beneficial beneficial JJ cord-022526-j9kg00qf 1999 2 effects effect NNS cord-022526-j9kg00qf 1999 3 have have VBP cord-022526-j9kg00qf 1999 4 been be VBN cord-022526-j9kg00qf 1999 5 described describe VBN cord-022526-j9kg00qf 1999 6 in in IN cord-022526-j9kg00qf 1999 7 experimental experimental JJ cord-022526-j9kg00qf 1999 8 models model NNS cord-022526-j9kg00qf 1999 9 of of IN cord-022526-j9kg00qf 1999 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 1999 11 , , , cord-022526-j9kg00qf 1999 12 acute acute JJ cord-022526-j9kg00qf 1999 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 1999 14 disease disease NN cord-022526-j9kg00qf 1999 15 , , , cord-022526-j9kg00qf 1999 16 and and CC cord-022526-j9kg00qf 1999 17 neonates neonate NNS cord-022526-j9kg00qf 1999 18 with with IN cord-022526-j9kg00qf 1999 19 sepsis sepsis NN cord-022526-j9kg00qf 1999 20 , , , cord-022526-j9kg00qf 1999 21 111 111 CD cord-022526-j9kg00qf 1999 22 , , , cord-022526-j9kg00qf 1999 23 [ [ -LRB- cord-022526-j9kg00qf 1999 24 115 115 CD cord-022526-j9kg00qf 1999 25 ] ] -RRB- cord-022526-j9kg00qf 1999 26 [ [ -LRB- cord-022526-j9kg00qf 1999 27 116 116 CD cord-022526-j9kg00qf 1999 28 ] ] -RRB- cord-022526-j9kg00qf 1999 29 [ [ -LRB- cord-022526-j9kg00qf 1999 30 117 117 CD cord-022526-j9kg00qf 1999 31 ] ] -RRB- cord-022526-j9kg00qf 1999 32 whereas whereas RB cord-022526-j9kg00qf 1999 33 in in IN cord-022526-j9kg00qf 1999 34 other other JJ cord-022526-j9kg00qf 1999 35 studies study NNS cord-022526-j9kg00qf 1999 36 , , , cord-022526-j9kg00qf 1999 37 antibodies antibody NNS cord-022526-j9kg00qf 1999 38 failed fail VBD cord-022526-j9kg00qf 1999 39 to to TO cord-022526-j9kg00qf 1999 40 protect protect VB cord-022526-j9kg00qf 1999 41 foals foal NNS cord-022526-j9kg00qf 1999 42 and and CC cord-022526-j9kg00qf 1999 43 horses horse NNS cord-022526-j9kg00qf 1999 44 against against IN cord-022526-j9kg00qf 1999 45 endotoxin endotoxin NN cord-022526-j9kg00qf 1999 46 effects effect NNS cord-022526-j9kg00qf 1999 47 . . . cord-022526-j9kg00qf 2000 1 118 118 CD cord-022526-j9kg00qf 2000 2 - - SYM cord-022526-j9kg00qf 2000 3 120 120 CD cord-022526-j9kg00qf 2001 1 Furthermore furthermore RB cord-022526-j9kg00qf 2001 2 , , , cord-022526-j9kg00qf 2001 3 administration administration NN cord-022526-j9kg00qf 2001 4 of of IN cord-022526-j9kg00qf 2001 5 a a DT cord-022526-j9kg00qf 2001 6 S. S. NNP cord-022526-j9kg00qf 2001 7 typhimurium typhimurium NN cord-022526-j9kg00qf 2001 8 antiserum antiserum NN cord-022526-j9kg00qf 2001 9 to to IN cord-022526-j9kg00qf 2001 10 foals foal NNS cord-022526-j9kg00qf 2001 11 was be VBD cord-022526-j9kg00qf 2001 12 associated associate VBN cord-022526-j9kg00qf 2001 13 with with IN cord-022526-j9kg00qf 2001 14 an an DT cord-022526-j9kg00qf 2001 15 increased increase VBN cord-022526-j9kg00qf 2001 16 respiratory respiratory JJ cord-022526-j9kg00qf 2001 17 rate rate NN cord-022526-j9kg00qf 2001 18 and and CC cord-022526-j9kg00qf 2001 19 higher high JJR cord-022526-j9kg00qf 2001 20 serum serum NN cord-022526-j9kg00qf 2001 21 activities activity NNS cord-022526-j9kg00qf 2001 22 of of IN cord-022526-j9kg00qf 2001 23 IL-6 IL-6 NNP cord-022526-j9kg00qf 2001 24 and and CC cord-022526-j9kg00qf 2001 25 TNF TNF NNP cord-022526-j9kg00qf 2001 26 . . . cord-022526-j9kg00qf 2002 1 118 118 CD cord-022526-j9kg00qf 2003 1 Various various JJ cord-022526-j9kg00qf 2003 2 equine equine JJ cord-022526-j9kg00qf 2003 3 serum serum NN cord-022526-j9kg00qf 2003 4 and and CC cord-022526-j9kg00qf 2003 5 plasma plasma NN cord-022526-j9kg00qf 2003 6 products product NNS cord-022526-j9kg00qf 2003 7 are be VBP cord-022526-j9kg00qf 2003 8 currently currently RB cord-022526-j9kg00qf 2003 9 commercially commercially RB cord-022526-j9kg00qf 2003 10 available available JJ cord-022526-j9kg00qf 2003 11 . . . cord-022526-j9kg00qf 2004 1 An an DT cord-022526-j9kg00qf 2004 2 antiserum antiserum NN cord-022526-j9kg00qf 2004 3 raised raise VBD cord-022526-j9kg00qf 2004 4 against against IN cord-022526-j9kg00qf 2004 5 the the DT cord-022526-j9kg00qf 2004 6 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2004 7 - - HYPH cord-022526-j9kg00qf 2004 8 core core NN cord-022526-j9kg00qf 2004 9 of of IN cord-022526-j9kg00qf 2004 10 S. S. NNP cord-022526-j9kg00qf 2004 11 typhimurium typhimurium NN cord-022526-j9kg00qf 2004 12 ( ( -LRB- cord-022526-j9kg00qf 2004 13 Endoserum Endoserum NNP cord-022526-j9kg00qf 2004 14 ) ) -RRB- cord-022526-j9kg00qf 2004 15 is be VBZ cord-022526-j9kg00qf 2004 16 available available JJ cord-022526-j9kg00qf 2004 17 for for IN cord-022526-j9kg00qf 2004 18 administration administration NN cord-022526-j9kg00qf 2004 19 to to TO cord-022526-j9kg00qf 2004 20 endotoxemic endotoxemic VB cord-022526-j9kg00qf 2004 21 horses horse NNS cord-022526-j9kg00qf 2004 22 at at IN cord-022526-j9kg00qf 2004 23 a a DT cord-022526-j9kg00qf 2004 24 recommended recommend VBN cord-022526-j9kg00qf 2004 25 dose dose NN cord-022526-j9kg00qf 2004 26 of of IN cord-022526-j9kg00qf 2004 27 1.5 1.5 CD cord-022526-j9kg00qf 2004 28 ml ml NNS cord-022526-j9kg00qf 2004 29 / / SYM cord-022526-j9kg00qf 2004 30 kg kg NN cord-022526-j9kg00qf 2004 31 body body NN cord-022526-j9kg00qf 2004 32 mass mass NN cord-022526-j9kg00qf 2004 33 . . . cord-022526-j9kg00qf 2005 1 Diluting dilute VBG cord-022526-j9kg00qf 2005 2 the the DT cord-022526-j9kg00qf 2005 3 serum serum NN cord-022526-j9kg00qf 2005 4 ten ten CD cord-022526-j9kg00qf 2005 5 - - HYPH cord-022526-j9kg00qf 2005 6 to to IN cord-022526-j9kg00qf 2005 7 twentyfold twentyfold RB cord-022526-j9kg00qf 2005 8 in in IN cord-022526-j9kg00qf 2005 9 crystalloid crystalloid JJ cord-022526-j9kg00qf 2005 10 intravenous intravenous JJ cord-022526-j9kg00qf 2005 11 solutions solution NNS cord-022526-j9kg00qf 2005 12 , , , cord-022526-j9kg00qf 2005 13 administering administer VBG cord-022526-j9kg00qf 2005 14 it -PRON- PRP cord-022526-j9kg00qf 2005 15 slowly slowly RB cord-022526-j9kg00qf 2005 16 over over IN cord-022526-j9kg00qf 2005 17 1 1 CD cord-022526-j9kg00qf 2005 18 to to IN cord-022526-j9kg00qf 2005 19 2 2 CD cord-022526-j9kg00qf 2005 20 hours hour NNS cord-022526-j9kg00qf 2005 21 , , , cord-022526-j9kg00qf 2005 22 and and CC cord-022526-j9kg00qf 2005 23 monitoring monitor VBG cord-022526-j9kg00qf 2005 24 the the DT cord-022526-j9kg00qf 2005 25 patient patient NN cord-022526-j9kg00qf 2005 26 for for IN cord-022526-j9kg00qf 2005 27 adverse adverse JJ cord-022526-j9kg00qf 2005 28 reactions reaction NNS cord-022526-j9kg00qf 2005 29 is be VBZ cord-022526-j9kg00qf 2005 30 advisable advisable JJ cord-022526-j9kg00qf 2005 31 . . . cord-022526-j9kg00qf 2006 1 Although although IN cord-022526-j9kg00qf 2006 2 the the DT cord-022526-j9kg00qf 2006 3 product product NN cord-022526-j9kg00qf 2006 4 is be VBZ cord-022526-j9kg00qf 2006 5 marketed market VBN cord-022526-j9kg00qf 2006 6 for for IN cord-022526-j9kg00qf 2006 7 use use NN cord-022526-j9kg00qf 2006 8 in in IN cord-022526-j9kg00qf 2006 9 foals foal NNS cord-022526-j9kg00qf 2006 10 with with IN cord-022526-j9kg00qf 2006 11 failure failure NN cord-022526-j9kg00qf 2006 12 of of IN cord-022526-j9kg00qf 2006 13 passive passive JJ cord-022526-j9kg00qf 2006 14 transfer transfer NN cord-022526-j9kg00qf 2006 15 , , , cord-022526-j9kg00qf 2006 16 adverse adverse JJ cord-022526-j9kg00qf 2006 17 effects effect NNS cord-022526-j9kg00qf 2006 18 have have VBP cord-022526-j9kg00qf 2006 19 been be VBN cord-022526-j9kg00qf 2006 20 reported report VBN cord-022526-j9kg00qf 2006 21 , , , cord-022526-j9kg00qf 2006 22 118 118 CD cord-022526-j9kg00qf 2006 23 and and CC cord-022526-j9kg00qf 2006 24 one one PRP cord-022526-j9kg00qf 2006 25 should should MD cord-022526-j9kg00qf 2006 26 use use VB cord-022526-j9kg00qf 2006 27 caution caution NN cord-022526-j9kg00qf 2006 28 when when WRB cord-022526-j9kg00qf 2006 29 administering administer VBG cord-022526-j9kg00qf 2006 30 it -PRON- PRP cord-022526-j9kg00qf 2006 31 to to IN cord-022526-j9kg00qf 2006 32 neonates neonate NNS cord-022526-j9kg00qf 2006 33 . . . cord-022526-j9kg00qf 2007 1 Plasma plasma NN cord-022526-j9kg00qf 2007 2 from from IN cord-022526-j9kg00qf 2007 3 donors donor NNS cord-022526-j9kg00qf 2007 4 inoculated inoculate VBN cord-022526-j9kg00qf 2007 5 with with IN cord-022526-j9kg00qf 2007 6 J5 J5 NNP cord-022526-j9kg00qf 2007 7 ( ( -LRB- cord-022526-j9kg00qf 2007 8 E. E. NNP cord-022526-j9kg00qf 2007 9 coli coli NNS cord-022526-j9kg00qf 2007 10 ) ) -RRB- cord-022526-j9kg00qf 2007 11 and and CC cord-022526-j9kg00qf 2007 12 S. S. NNP cord-022526-j9kg00qf 2007 13 typhimurium typhimurium NN cord-022526-j9kg00qf 2007 14 ( ( -LRB- cord-022526-j9kg00qf 2008 1 Re re IN cord-022526-j9kg00qf 2008 2 mutant mutant JJ cord-022526-j9kg00qf 2008 3 ) ) -RRB- cord-022526-j9kg00qf 2008 4 is be VBZ cord-022526-j9kg00qf 2008 5 available available JJ cord-022526-j9kg00qf 2008 6 under under IN cord-022526-j9kg00qf 2008 7 a a DT cord-022526-j9kg00qf 2008 8 restricted restricted JJ cord-022526-j9kg00qf 2008 9 license license NN cord-022526-j9kg00qf 2008 10 ( ( -LRB- cord-022526-j9kg00qf 2008 11 Polymune Polymune NNP cord-022526-j9kg00qf 2008 12 - - HYPH cord-022526-j9kg00qf 2008 13 J J NNP cord-022526-j9kg00qf 2008 14 , , , cord-022526-j9kg00qf 2008 15 Vet Vet NNP cord-022526-j9kg00qf 2008 16 Dynamics Dynamics NNP cord-022526-j9kg00qf 2008 17 , , , cord-022526-j9kg00qf 2008 18 Inc. Inc. NNP cord-022526-j9kg00qf 2008 19 , , , cord-022526-j9kg00qf 2008 20 San San NNP cord-022526-j9kg00qf 2008 21 Louis Louis NNP cord-022526-j9kg00qf 2008 22 Obispo Obispo NNP cord-022526-j9kg00qf 2008 23 , , , cord-022526-j9kg00qf 2008 24 California California NNP cord-022526-j9kg00qf 2008 25 ) ) -RRB- cord-022526-j9kg00qf 2008 26 . . . cord-022526-j9kg00qf 2009 1 The the DT cord-022526-j9kg00qf 2009 2 manufacturer manufacturer NN cord-022526-j9kg00qf 2009 3 recommends recommend VBZ cord-022526-j9kg00qf 2009 4 administration administration NN cord-022526-j9kg00qf 2009 5 of of IN cord-022526-j9kg00qf 2009 6 at at RB cord-022526-j9kg00qf 2009 7 least least JJS cord-022526-j9kg00qf 2009 8 1 1 CD cord-022526-j9kg00qf 2009 9 to to IN cord-022526-j9kg00qf 2009 10 2 2 CD cord-022526-j9kg00qf 2009 11 L l NN cord-022526-j9kg00qf 2009 12 in in IN cord-022526-j9kg00qf 2009 13 cases case NNS cord-022526-j9kg00qf 2009 14 of of IN cord-022526-j9kg00qf 2009 15 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2009 16 . . . cord-022526-j9kg00qf 2010 1 In in IN cord-022526-j9kg00qf 2010 2 addition addition NN cord-022526-j9kg00qf 2010 3 , , , cord-022526-j9kg00qf 2010 4 hyperimmune hyperimmune NNP cord-022526-j9kg00qf 2010 5 plasma plasma NN cord-022526-j9kg00qf 2010 6 , , , cord-022526-j9kg00qf 2010 7 which which WDT cord-022526-j9kg00qf 2010 8 has have VBZ cord-022526-j9kg00qf 2010 9 a a DT cord-022526-j9kg00qf 2010 10 guaranteed guarantee VBN cord-022526-j9kg00qf 2010 11 minimum minimum JJ cord-022526-j9kg00qf 2010 12 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 2010 13 G g NN cord-022526-j9kg00qf 2010 14 content content NN cord-022526-j9kg00qf 2010 15 but but CC cord-022526-j9kg00qf 2010 16 does do VBZ cord-022526-j9kg00qf 2010 17 not not RB cord-022526-j9kg00qf 2010 18 contain contain VB cord-022526-j9kg00qf 2010 19 specific specific JJ cord-022526-j9kg00qf 2010 20 antiendotoxin antiendotoxin NN cord-022526-j9kg00qf 2010 21 antibodies antibody NNS cord-022526-j9kg00qf 2010 22 ( ( -LRB- cord-022526-j9kg00qf 2011 1 Hi hi UH cord-022526-j9kg00qf 2011 2 - - HYPH cord-022526-j9kg00qf 2011 3 Gamm Gamm NNP cord-022526-j9kg00qf 2011 4 Equi Equi NNP cord-022526-j9kg00qf 2011 5 , , , cord-022526-j9kg00qf 2011 6 Lake Lake NNP cord-022526-j9kg00qf 2011 7 Immunogenics Immunogenics NNP cord-022526-j9kg00qf 2011 8 , , , cord-022526-j9kg00qf 2011 9 Inc. Inc. NNP cord-022526-j9kg00qf 2011 10 , , , cord-022526-j9kg00qf 2011 11 Ontario Ontario NNP cord-022526-j9kg00qf 2011 12 , , , cord-022526-j9kg00qf 2011 13 New New NNP cord-022526-j9kg00qf 2011 14 York York NNP cord-022526-j9kg00qf 2011 15 ; ; : cord-022526-j9kg00qf 2011 16 Polymune Polymune NNP cord-022526-j9kg00qf 2011 17 and and CC cord-022526-j9kg00qf 2011 18 Polymune Polymune NNP cord-022526-j9kg00qf 2011 19 - - HYPH cord-022526-j9kg00qf 2011 20 Plus Plus NNP cord-022526-j9kg00qf 2011 21 , , , cord-022526-j9kg00qf 2011 22 Vet Vet NNP cord-022526-j9kg00qf 2011 23 Dynamics Dynamics NNP cord-022526-j9kg00qf 2011 24 , , , cord-022526-j9kg00qf 2011 25 Inc. Inc. NNP cord-022526-j9kg00qf 2011 26 ) ) -RRB- cord-022526-j9kg00qf 2011 27 , , , cord-022526-j9kg00qf 2011 28 is be VBZ cord-022526-j9kg00qf 2011 29 marketed market VBN cord-022526-j9kg00qf 2011 30 for for IN cord-022526-j9kg00qf 2011 31 treatment treatment NN cord-022526-j9kg00qf 2011 32 of of IN cord-022526-j9kg00qf 2011 33 failure failure NN cord-022526-j9kg00qf 2011 34 of of IN cord-022526-j9kg00qf 2011 35 passive passive JJ cord-022526-j9kg00qf 2011 36 transfer transfer NN cord-022526-j9kg00qf 2011 37 , , , cord-022526-j9kg00qf 2011 38 and and CC cord-022526-j9kg00qf 2011 39 many many JJ cord-022526-j9kg00qf 2011 40 clinicians clinician NNS cord-022526-j9kg00qf 2011 41 use use VBP cord-022526-j9kg00qf 2011 42 it -PRON- PRP cord-022526-j9kg00qf 2011 43 to to TO cord-022526-j9kg00qf 2011 44 treat treat VB cord-022526-j9kg00qf 2011 45 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2011 46 and and CC cord-022526-j9kg00qf 2011 47 sepsis sepsis NN cord-022526-j9kg00qf 2011 48 . . . cord-022526-j9kg00qf 2012 1 In in IN cord-022526-j9kg00qf 2012 2 addition addition NN cord-022526-j9kg00qf 2012 3 to to IN cord-022526-j9kg00qf 2012 4 antibodies antibody NNS cord-022526-j9kg00qf 2012 5 and and CC cord-022526-j9kg00qf 2012 6 protein protein NN cord-022526-j9kg00qf 2012 7 , , , cord-022526-j9kg00qf 2012 8 plasma plasma NN cord-022526-j9kg00qf 2012 9 contains contain VBZ cord-022526-j9kg00qf 2012 10 active active JJ cord-022526-j9kg00qf 2012 11 constituents constituent NNS cord-022526-j9kg00qf 2012 12 such such JJ cord-022526-j9kg00qf 2012 13 as as IN cord-022526-j9kg00qf 2012 14 complement complement JJ cord-022526-j9kg00qf 2012 15 components component NNS cord-022526-j9kg00qf 2012 16 , , , cord-022526-j9kg00qf 2012 17 fibronectin fibronectin NN cord-022526-j9kg00qf 2012 18 , , , cord-022526-j9kg00qf 2012 19 clotting clotting NN cord-022526-j9kg00qf 2012 20 factors factor NNS cord-022526-j9kg00qf 2012 21 , , , cord-022526-j9kg00qf 2012 22 and and CC cord-022526-j9kg00qf 2012 23 AT AT NNP cord-022526-j9kg00qf 2012 24 III III NNP cord-022526-j9kg00qf 2012 25 116 116 CD cord-022526-j9kg00qf 2012 26 and and CC cord-022526-j9kg00qf 2012 27 therefore therefore RB cord-022526-j9kg00qf 2012 28 may may MD cord-022526-j9kg00qf 2012 29 be be VB cord-022526-j9kg00qf 2012 30 particularly particularly RB cord-022526-j9kg00qf 2012 31 useful useful JJ cord-022526-j9kg00qf 2012 32 in in IN cord-022526-j9kg00qf 2012 33 patients patient NNS cord-022526-j9kg00qf 2012 34 with with IN cord-022526-j9kg00qf 2012 35 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2012 36 - - HYPH cord-022526-j9kg00qf 2012 37 induced induce VBN cord-022526-j9kg00qf 2012 38 coagulopathy coagulopathy NN cord-022526-j9kg00qf 2012 39 . . . cord-022526-j9kg00qf 2013 1 Volumes volume NNS cord-022526-j9kg00qf 2013 2 of of IN cord-022526-j9kg00qf 2013 3 2 2 CD cord-022526-j9kg00qf 2013 4 to to TO cord-022526-j9kg00qf 2013 5 10 10 CD cord-022526-j9kg00qf 2013 6 ml ml NNS cord-022526-j9kg00qf 2013 7 / / SYM cord-022526-j9kg00qf 2013 8 kg kg NN cord-022526-j9kg00qf 2013 9 body body NN cord-022526-j9kg00qf 2013 10 mass mass NN cord-022526-j9kg00qf 2013 11 of of IN cord-022526-j9kg00qf 2013 12 hyperimmune hyperimmune NNP cord-022526-j9kg00qf 2013 13 plasma plasma NN cord-022526-j9kg00qf 2013 14 have have VBP cord-022526-j9kg00qf 2013 15 been be VBN cord-022526-j9kg00qf 2013 16 recommended recommend VBN cord-022526-j9kg00qf 2013 17 for for IN cord-022526-j9kg00qf 2013 18 use use NN cord-022526-j9kg00qf 2013 19 in in IN cord-022526-j9kg00qf 2013 20 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 2013 21 patients patient NNS cord-022526-j9kg00qf 2013 22 . . . cord-022526-j9kg00qf 2014 1 56 56 CD cord-022526-j9kg00qf 2014 2 , , , cord-022526-j9kg00qf 2014 3 121 121 CD cord-022526-j9kg00qf 2014 4 Polymyxin Polymyxin NNP cord-022526-j9kg00qf 2014 5 B B NNP cord-022526-j9kg00qf 2014 6 Polymyxin Polymyxin NNP cord-022526-j9kg00qf 2014 7 B B NNP cord-022526-j9kg00qf 2014 8 is be VBZ cord-022526-j9kg00qf 2014 9 a a DT cord-022526-j9kg00qf 2014 10 cationic cationic JJ cord-022526-j9kg00qf 2014 11 polypeptide polypeptide NN cord-022526-j9kg00qf 2014 12 antibiotic antibiotic NN cord-022526-j9kg00qf 2014 13 that that WDT cord-022526-j9kg00qf 2014 14 binds bind VBZ cord-022526-j9kg00qf 2014 15 to to IN cord-022526-j9kg00qf 2014 16 the the DT cord-022526-j9kg00qf 2014 17 anionic anionic JJ cord-022526-j9kg00qf 2014 18 lipid lipid NN cord-022526-j9kg00qf 2014 19 A a DT cord-022526-j9kg00qf 2014 20 portion portion NN cord-022526-j9kg00qf 2014 21 of of IN cord-022526-j9kg00qf 2014 22 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2014 23 and and CC cord-022526-j9kg00qf 2014 24 neutralizes neutralize VBZ cord-022526-j9kg00qf 2014 25 its -PRON- PRP$ cord-022526-j9kg00qf 2014 26 endotoxin endotoxin NN cord-022526-j9kg00qf 2014 27 capacity capacity NN cord-022526-j9kg00qf 2014 28 . . . cord-022526-j9kg00qf 2015 1 122 122 CD cord-022526-j9kg00qf 2016 1 At at IN cord-022526-j9kg00qf 2016 2 dosages dosage NNS cord-022526-j9kg00qf 2016 3 required require VBN cord-022526-j9kg00qf 2016 4 for for IN cord-022526-j9kg00qf 2016 5 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 2016 6 activity activity NN cord-022526-j9kg00qf 2016 7 , , , cord-022526-j9kg00qf 2016 8 polymyxin polymyxin NNP cord-022526-j9kg00qf 2016 9 B B NNP cord-022526-j9kg00qf 2016 10 carries carry VBZ cord-022526-j9kg00qf 2016 11 the the DT cord-022526-j9kg00qf 2016 12 risk risk NN cord-022526-j9kg00qf 2016 13 of of IN cord-022526-j9kg00qf 2016 14 respiratory respiratory JJ cord-022526-j9kg00qf 2016 15 paralysis paralysis NN cord-022526-j9kg00qf 2016 16 and and CC cord-022526-j9kg00qf 2016 17 ototoxic ototoxic RB cord-022526-j9kg00qf 2016 18 , , , cord-022526-j9kg00qf 2016 19 nephrotoxic nephrotoxic NNP cord-022526-j9kg00qf 2016 20 , , , cord-022526-j9kg00qf 2016 21 and and CC cord-022526-j9kg00qf 2016 22 neurotoxic neurotoxic JJ cord-022526-j9kg00qf 2016 23 side side NN cord-022526-j9kg00qf 2016 24 effects effect NNS cord-022526-j9kg00qf 2016 25 ; ; : cord-022526-j9kg00qf 2016 26 however however RB cord-022526-j9kg00qf 2016 27 , , , cord-022526-j9kg00qf 2016 28 a a DT cord-022526-j9kg00qf 2016 29 much much RB cord-022526-j9kg00qf 2016 30 lower low JJR cord-022526-j9kg00qf 2016 31 dose dose NN cord-022526-j9kg00qf 2016 32 is be VBZ cord-022526-j9kg00qf 2016 33 required require VBN cord-022526-j9kg00qf 2016 34 for for IN cord-022526-j9kg00qf 2016 35 endotoxin endotoxin NN cord-022526-j9kg00qf 2016 36 - - HYPH cord-022526-j9kg00qf 2016 37 binding bind VBG cord-022526-j9kg00qf 2016 38 activity activity NN cord-022526-j9kg00qf 2016 39 . . . cord-022526-j9kg00qf 2017 1 The the DT cord-022526-j9kg00qf 2017 2 effects effect NNS cord-022526-j9kg00qf 2017 3 of of IN cord-022526-j9kg00qf 2017 4 polymyxin polymyxin NN cord-022526-j9kg00qf 2017 5 B b NN cord-022526-j9kg00qf 2017 6 in in IN cord-022526-j9kg00qf 2017 7 horses horse NNS cord-022526-j9kg00qf 2017 8 have have VBP cord-022526-j9kg00qf 2017 9 been be VBN cord-022526-j9kg00qf 2017 10 evaluated evaluate VBN cord-022526-j9kg00qf 2017 11 in in IN cord-022526-j9kg00qf 2017 12 different different JJ cord-022526-j9kg00qf 2017 13 experimental experimental JJ cord-022526-j9kg00qf 2017 14 models model NNS cord-022526-j9kg00qf 2017 15 . . . cord-022526-j9kg00qf 2018 1 118 118 CD cord-022526-j9kg00qf 2018 2 , , , cord-022526-j9kg00qf 2018 3 122 122 CD cord-022526-j9kg00qf 2018 4 , , , cord-022526-j9kg00qf 2018 5 123 123 CD cord-022526-j9kg00qf 2019 1 In in IN cord-022526-j9kg00qf 2019 2 an an DT cord-022526-j9kg00qf 2019 3 in in IN cord-022526-j9kg00qf 2019 4 vivo vivo NN cord-022526-j9kg00qf 2019 5 study study NN cord-022526-j9kg00qf 2019 6 in in IN cord-022526-j9kg00qf 2019 7 foals foal NNS cord-022526-j9kg00qf 2019 8 , , , cord-022526-j9kg00qf 2019 9 treatment treatment NN cord-022526-j9kg00qf 2019 10 with with IN cord-022526-j9kg00qf 2019 11 polymyxin polymyxin NN cord-022526-j9kg00qf 2019 12 B B NNP cord-022526-j9kg00qf 2019 13 at at IN cord-022526-j9kg00qf 2019 14 a a DT cord-022526-j9kg00qf 2019 15 dosage dosage NN cord-022526-j9kg00qf 2019 16 of of IN cord-022526-j9kg00qf 2019 17 6000 6000 CD cord-022526-j9kg00qf 2019 18 U U NNP cord-022526-j9kg00qf 2019 19 / / SYM cord-022526-j9kg00qf 2019 20 kg kg NN cord-022526-j9kg00qf 2019 21 body body NN cord-022526-j9kg00qf 2019 22 mass mass NN cord-022526-j9kg00qf 2019 23 before before IN cord-022526-j9kg00qf 2019 24 infusion infusion NN cord-022526-j9kg00qf 2019 25 with with IN cord-022526-j9kg00qf 2019 26 S. S. NNP cord-022526-j9kg00qf 2019 27 typhimurium typhimurium NN cord-022526-j9kg00qf 2019 28 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2019 29 resulted result VBD cord-022526-j9kg00qf 2019 30 in in IN cord-022526-j9kg00qf 2019 31 significantly significantly RB cord-022526-j9kg00qf 2019 32 less less RBR cord-022526-j9kg00qf 2019 33 severe severe JJ cord-022526-j9kg00qf 2019 34 elevations elevation NNS cord-022526-j9kg00qf 2019 35 of of IN cord-022526-j9kg00qf 2019 36 body body NN cord-022526-j9kg00qf 2019 37 temperature temperature NN cord-022526-j9kg00qf 2019 38 , , , cord-022526-j9kg00qf 2019 39 respiratory respiratory JJ cord-022526-j9kg00qf 2019 40 rate rate NN cord-022526-j9kg00qf 2019 41 , , , cord-022526-j9kg00qf 2019 42 and and CC cord-022526-j9kg00qf 2019 43 serum serum NN cord-022526-j9kg00qf 2019 44 activities activity NNS cord-022526-j9kg00qf 2019 45 of of IN cord-022526-j9kg00qf 2019 46 TNF TNF NNP cord-022526-j9kg00qf 2019 47 and and CC cord-022526-j9kg00qf 2019 48 IL-6 IL-6 NNP cord-022526-j9kg00qf 2019 49 compared compare VBN cord-022526-j9kg00qf 2019 50 with with IN cord-022526-j9kg00qf 2019 51 untreated untreated JJ cord-022526-j9kg00qf 2019 52 controls control NNS cord-022526-j9kg00qf 2019 53 . . . cord-022526-j9kg00qf 2020 1 118 118 CD cord-022526-j9kg00qf 2021 1 Similarly similarly RB cord-022526-j9kg00qf 2021 2 , , , cord-022526-j9kg00qf 2021 3 polymyxin polymyxin NN cord-022526-j9kg00qf 2021 4 B b NN cord-022526-j9kg00qf 2021 5 treatment treatment NN cord-022526-j9kg00qf 2021 6 of of IN cord-022526-j9kg00qf 2021 7 adult adult NN cord-022526-j9kg00qf 2021 8 horses horse NNS cord-022526-j9kg00qf 2021 9 given give VBN cord-022526-j9kg00qf 2021 10 endotoxin endotoxin NN cord-022526-j9kg00qf 2021 11 significantly significantly RB cord-022526-j9kg00qf 2021 12 ameliorated ameliorate VBD cord-022526-j9kg00qf 2021 13 clinical clinical JJ cord-022526-j9kg00qf 2021 14 signs sign NNS cord-022526-j9kg00qf 2021 15 and and CC cord-022526-j9kg00qf 2021 16 decreased decrease VBD cord-022526-j9kg00qf 2021 17 plasma plasma NN cord-022526-j9kg00qf 2021 18 TNF tnf NN cord-022526-j9kg00qf 2021 19 activity activity NN cord-022526-j9kg00qf 2021 20 . . . cord-022526-j9kg00qf 2022 1 124 124 CD cord-022526-j9kg00qf 2023 1 In in IN cord-022526-j9kg00qf 2023 2 the the DT cord-022526-j9kg00qf 2023 3 latter latter JJ cord-022526-j9kg00qf 2023 4 study study NN cord-022526-j9kg00qf 2023 5 , , , cord-022526-j9kg00qf 2023 6 benefits benefit NNS cord-022526-j9kg00qf 2023 7 of of IN cord-022526-j9kg00qf 2023 8 treatment treatment NN cord-022526-j9kg00qf 2023 9 were be VBD cord-022526-j9kg00qf 2023 10 also also RB cord-022526-j9kg00qf 2023 11 evident evident JJ cord-022526-j9kg00qf 2023 12 at at IN cord-022526-j9kg00qf 2023 13 lower low JJR cord-022526-j9kg00qf 2023 14 dosages dosage NNS cord-022526-j9kg00qf 2023 15 of of IN cord-022526-j9kg00qf 2023 16 polymyxin polymyxin NN cord-022526-j9kg00qf 2023 17 B B NNP cord-022526-j9kg00qf 2023 18 ( ( -LRB- cord-022526-j9kg00qf 2023 19 1000 1000 CD cord-022526-j9kg00qf 2023 20 and and CC cord-022526-j9kg00qf 2023 21 5000 5000 CD cord-022526-j9kg00qf 2023 22 U U NNP cord-022526-j9kg00qf 2023 23 / / SYM cord-022526-j9kg00qf 2023 24 kg kg NN cord-022526-j9kg00qf 2023 25 body body NN cord-022526-j9kg00qf 2023 26 mass mass NN cord-022526-j9kg00qf 2023 27 ) ) -RRB- cord-022526-j9kg00qf 2023 28 and and CC cord-022526-j9kg00qf 2023 29 administration administration NN cord-022526-j9kg00qf 2023 30 of of IN cord-022526-j9kg00qf 2023 31 polymyxin polymyxin NNP cord-022526-j9kg00qf 2023 32 B B NNP cord-022526-j9kg00qf 2023 33 1 1 CD cord-022526-j9kg00qf 2023 34 hour hour NN cord-022526-j9kg00qf 2023 35 after after IN cord-022526-j9kg00qf 2023 36 the the DT cord-022526-j9kg00qf 2023 37 start start NN cord-022526-j9kg00qf 2023 38 of of IN cord-022526-j9kg00qf 2023 39 endotoxin endotoxin NN cord-022526-j9kg00qf 2023 40 infusion infusion NN cord-022526-j9kg00qf 2023 41 . . . cord-022526-j9kg00qf 2024 1 Conversely conversely RB cord-022526-j9kg00qf 2024 2 , , , cord-022526-j9kg00qf 2024 3 polymyxin polymyxin NNP cord-022526-j9kg00qf 2024 4 B B NNP cord-022526-j9kg00qf 2024 5 failed fail VBD cord-022526-j9kg00qf 2024 6 to to TO cord-022526-j9kg00qf 2024 7 ameliorate ameliorate VB cord-022526-j9kg00qf 2024 8 clinical clinical JJ cord-022526-j9kg00qf 2024 9 signs sign NNS cord-022526-j9kg00qf 2024 10 of of IN cord-022526-j9kg00qf 2024 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2024 12 or or CC cord-022526-j9kg00qf 2024 13 prevent prevent VB cord-022526-j9kg00qf 2024 14 the the DT cord-022526-j9kg00qf 2024 15 development development NN cord-022526-j9kg00qf 2024 16 of of IN cord-022526-j9kg00qf 2024 17 coagulopathy coagulopathy NN cord-022526-j9kg00qf 2024 18 , , , cord-022526-j9kg00qf 2024 19 acidosis acidosis NN cord-022526-j9kg00qf 2024 20 , , , cord-022526-j9kg00qf 2024 21 lameness lameness NN cord-022526-j9kg00qf 2024 22 , , , cord-022526-j9kg00qf 2024 23 and and CC cord-022526-j9kg00qf 2024 24 shock shock NN cord-022526-j9kg00qf 2024 25 in in IN cord-022526-j9kg00qf 2024 26 experimental experimental JJ cord-022526-j9kg00qf 2024 27 carbohydrate carbohydrate NN cord-022526-j9kg00qf 2024 28 overload overload NN cord-022526-j9kg00qf 2024 29 . . . cord-022526-j9kg00qf 2025 1 125 125 CD cord-022526-j9kg00qf 2025 2 Side side NN cord-022526-j9kg00qf 2025 3 effects effect NNS cord-022526-j9kg00qf 2025 4 suggestive suggestive JJ cord-022526-j9kg00qf 2025 5 of of IN cord-022526-j9kg00qf 2025 6 neurotoxicity neurotoxicity NN cord-022526-j9kg00qf 2025 7 appeared appear VBD cord-022526-j9kg00qf 2025 8 after after IN cord-022526-j9kg00qf 2025 9 repeated repeat VBN cord-022526-j9kg00qf 2025 10 administration administration NN cord-022526-j9kg00qf 2025 11 of of IN cord-022526-j9kg00qf 2025 12 5 5 CD cord-022526-j9kg00qf 2025 13 mg mg NNP cord-022526-j9kg00qf 2025 14 / / SYM cord-022526-j9kg00qf 2025 15 kg kg NNP cord-022526-j9kg00qf 2025 16 body body NN cord-022526-j9kg00qf 2025 17 mass mass NN cord-022526-j9kg00qf 2025 18 ( ( -LRB- cord-022526-j9kg00qf 2025 19 36,000 36,000 CD cord-022526-j9kg00qf 2025 20 U U NNP cord-022526-j9kg00qf 2025 21 / / SYM cord-022526-j9kg00qf 2025 22 kg kg NNP cord-022526-j9kg00qf 2025 23 ) ) -RRB- cord-022526-j9kg00qf 2025 24 and and CC cord-022526-j9kg00qf 2025 25 in in IN cord-022526-j9kg00qf 2025 26 milder mild JJR cord-022526-j9kg00qf 2025 27 form form NN cord-022526-j9kg00qf 2025 28 , , , cord-022526-j9kg00qf 2025 29 2.5 2.5 CD cord-022526-j9kg00qf 2025 30 mg mg NNP cord-022526-j9kg00qf 2025 31 / / SYM cord-022526-j9kg00qf 2025 32 kg kg NNP cord-022526-j9kg00qf 2025 33 body body NN cord-022526-j9kg00qf 2025 34 mass mass NN cord-022526-j9kg00qf 2025 35 ( ( -LRB- cord-022526-j9kg00qf 2025 36 18,000 18,000 CD cord-022526-j9kg00qf 2025 37 U U NNP cord-022526-j9kg00qf 2025 38 / / SYM cord-022526-j9kg00qf 2025 39 kg kg NNP cord-022526-j9kg00qf 2025 40 ) ) -RRB- cord-022526-j9kg00qf 2025 41 polymyxin polymyxin NNP cord-022526-j9kg00qf 2025 42 B. B. NNP cord-022526-j9kg00qf 2025 43 Nephrotoxicity Nephrotoxicity NNP cord-022526-j9kg00qf 2025 44 was be VBD cord-022526-j9kg00qf 2025 45 not not RB cord-022526-j9kg00qf 2025 46 observed observe VBN cord-022526-j9kg00qf 2025 47 . . . cord-022526-j9kg00qf 2026 1 Currently currently RB cord-022526-j9kg00qf 2026 2 , , , cord-022526-j9kg00qf 2026 3 use use NN cord-022526-j9kg00qf 2026 4 of of IN cord-022526-j9kg00qf 2026 5 polymyxin polymyxin NN cord-022526-j9kg00qf 2026 6 B b NN cord-022526-j9kg00qf 2026 7 in in IN cord-022526-j9kg00qf 2026 8 equine equine JJ cord-022526-j9kg00qf 2026 9 patients patient NNS cord-022526-j9kg00qf 2026 10 is be VBZ cord-022526-j9kg00qf 2026 11 recommended recommend VBN cord-022526-j9kg00qf 2026 12 at at IN cord-022526-j9kg00qf 2026 13 dosages dosage NNS cord-022526-j9kg00qf 2026 14 of of IN cord-022526-j9kg00qf 2026 15 1000 1000 CD cord-022526-j9kg00qf 2026 16 to to IN cord-022526-j9kg00qf 2026 17 5000 5000 CD cord-022526-j9kg00qf 2026 18 U U NNP cord-022526-j9kg00qf 2026 19 / / SYM cord-022526-j9kg00qf 2026 20 kg kg NN cord-022526-j9kg00qf 2026 21 body body NN cord-022526-j9kg00qf 2026 22 mass mass NN cord-022526-j9kg00qf 2026 23 every every DT cord-022526-j9kg00qf 2026 24 8 8 CD cord-022526-j9kg00qf 2026 25 to to TO cord-022526-j9kg00qf 2026 26 12 12 CD cord-022526-j9kg00qf 2026 27 hours hour NNS cord-022526-j9kg00qf 2026 28 . . . cord-022526-j9kg00qf 2027 1 126 126 CD cord-022526-j9kg00qf 2027 2 One one PRP cord-022526-j9kg00qf 2027 3 should should MD cord-022526-j9kg00qf 2027 4 initiate initiate VB cord-022526-j9kg00qf 2027 5 treatment treatment NN cord-022526-j9kg00qf 2027 6 as as RB cord-022526-j9kg00qf 2027 7 early early RB cord-022526-j9kg00qf 2027 8 in in IN cord-022526-j9kg00qf 2027 9 the the DT cord-022526-j9kg00qf 2027 10 disease disease NN cord-022526-j9kg00qf 2027 11 process process NN cord-022526-j9kg00qf 2027 12 as as IN cord-022526-j9kg00qf 2027 13 possible possible JJ cord-022526-j9kg00qf 2027 14 , , , cord-022526-j9kg00qf 2027 15 because because IN cord-022526-j9kg00qf 2027 16 the the DT cord-022526-j9kg00qf 2027 17 beneficial beneficial JJ cord-022526-j9kg00qf 2027 18 effects effect NNS cord-022526-j9kg00qf 2027 19 of of IN cord-022526-j9kg00qf 2027 20 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2027 21 scavenging scavenging NN cord-022526-j9kg00qf 2027 22 are be VBP cord-022526-j9kg00qf 2027 23 limited limit VBN cord-022526-j9kg00qf 2027 24 to to IN cord-022526-j9kg00qf 2027 25 the the DT cord-022526-j9kg00qf 2027 26 first first JJ cord-022526-j9kg00qf 2027 27 24 24 CD cord-022526-j9kg00qf 2027 28 to to TO cord-022526-j9kg00qf 2027 29 48 48 CD cord-022526-j9kg00qf 2027 30 hours hour NNS cord-022526-j9kg00qf 2027 31 after after IN cord-022526-j9kg00qf 2027 32 the the DT cord-022526-j9kg00qf 2027 33 onset onset NN cord-022526-j9kg00qf 2027 34 of of IN cord-022526-j9kg00qf 2027 35 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2027 36 , , , cord-022526-j9kg00qf 2027 37 before before IN cord-022526-j9kg00qf 2027 38 tolerance tolerance NN cord-022526-j9kg00qf 2027 39 develops develop VBZ cord-022526-j9kg00qf 2027 40 . . . cord-022526-j9kg00qf 2028 1 Side side JJ cord-022526-j9kg00qf 2028 2 effects effect NNS cord-022526-j9kg00qf 2028 3 in in IN cord-022526-j9kg00qf 2028 4 the the DT cord-022526-j9kg00qf 2028 5 form form NN cord-022526-j9kg00qf 2028 6 of of IN cord-022526-j9kg00qf 2028 7 neuromuscular neuromuscular JJ cord-022526-j9kg00qf 2028 8 blockade blockade NN cord-022526-j9kg00qf 2028 9 and and CC cord-022526-j9kg00qf 2028 10 apnea apnea NN cord-022526-j9kg00qf 2028 11 , , , cord-022526-j9kg00qf 2028 12 which which WDT cord-022526-j9kg00qf 2028 13 necessitate necessitate VBP cord-022526-j9kg00qf 2028 14 slow slow JJ cord-022526-j9kg00qf 2028 15 infusion infusion NN cord-022526-j9kg00qf 2028 16 of of IN cord-022526-j9kg00qf 2028 17 the the DT cord-022526-j9kg00qf 2028 18 drug drug NN cord-022526-j9kg00qf 2028 19 in in IN cord-022526-j9kg00qf 2028 20 human human JJ cord-022526-j9kg00qf 2028 21 patients patient NNS cord-022526-j9kg00qf 2028 22 , , , cord-022526-j9kg00qf 2028 23 have have VBP cord-022526-j9kg00qf 2028 24 not not RB cord-022526-j9kg00qf 2028 25 been be VBN cord-022526-j9kg00qf 2028 26 observed observe VBN cord-022526-j9kg00qf 2028 27 in in IN cord-022526-j9kg00qf 2028 28 horses horse NNS cord-022526-j9kg00qf 2028 29 . . . cord-022526-j9kg00qf 2029 1 One one CD cord-022526-j9kg00qf 2029 2 therefore therefore RB cord-022526-j9kg00qf 2029 3 can can MD cord-022526-j9kg00qf 2029 4 administer administer VB cord-022526-j9kg00qf 2029 5 the the DT cord-022526-j9kg00qf 2029 6 entire entire JJ cord-022526-j9kg00qf 2029 7 dose dose NN cord-022526-j9kg00qf 2029 8 as as IN cord-022526-j9kg00qf 2029 9 a a DT cord-022526-j9kg00qf 2029 10 slow slow JJ cord-022526-j9kg00qf 2029 11 bolus bolus NN cord-022526-j9kg00qf 2029 12 . . . cord-022526-j9kg00qf 2030 1 If if IN cord-022526-j9kg00qf 2030 2 one one CD cord-022526-j9kg00qf 2030 3 uses use VBZ cord-022526-j9kg00qf 2030 4 polymyxin polymyxin NN cord-022526-j9kg00qf 2030 5 B b NN cord-022526-j9kg00qf 2030 6 in in IN cord-022526-j9kg00qf 2030 7 horses horse NNS cord-022526-j9kg00qf 2030 8 with with IN cord-022526-j9kg00qf 2030 9 hypovolemia hypovolemia NN cord-022526-j9kg00qf 2030 10 , , , cord-022526-j9kg00qf 2030 11 dehydration dehydration NN cord-022526-j9kg00qf 2030 12 , , , cord-022526-j9kg00qf 2030 13 or or CC cord-022526-j9kg00qf 2030 14 azotemia azotemia NN cord-022526-j9kg00qf 2030 15 , , , cord-022526-j9kg00qf 2030 16 one one PRP cord-022526-j9kg00qf 2030 17 should should MD cord-022526-j9kg00qf 2030 18 attempt attempt VB cord-022526-j9kg00qf 2030 19 to to TO cord-022526-j9kg00qf 2030 20 improve improve VB cord-022526-j9kg00qf 2030 21 peripheral peripheral JJ cord-022526-j9kg00qf 2030 22 tissue tissue NN cord-022526-j9kg00qf 2030 23 perfusion perfusion NN cord-022526-j9kg00qf 2030 24 , , , cord-022526-j9kg00qf 2030 25 minimize minimize VB cord-022526-j9kg00qf 2030 26 the the DT cord-022526-j9kg00qf 2030 27 polymyxin polymyxin NN cord-022526-j9kg00qf 2030 28 B B NNP cord-022526-j9kg00qf 2030 29 dose dose NN cord-022526-j9kg00qf 2030 30 , , , cord-022526-j9kg00qf 2030 31 and and CC cord-022526-j9kg00qf 2030 32 closely closely RB cord-022526-j9kg00qf 2030 33 monitor monitor VB cord-022526-j9kg00qf 2030 34 patients patient NNS cord-022526-j9kg00qf 2030 35 for for IN cord-022526-j9kg00qf 2030 36 nephrotoxicity nephrotoxicity NN cord-022526-j9kg00qf 2030 37 . . . cord-022526-j9kg00qf 2031 1 Close close JJ cord-022526-j9kg00qf 2031 2 monitoring monitoring NN cord-022526-j9kg00qf 2031 3 is be VBZ cord-022526-j9kg00qf 2031 4 also also RB cord-022526-j9kg00qf 2031 5 important important JJ cord-022526-j9kg00qf 2031 6 if if IN cord-022526-j9kg00qf 2031 7 one one PRP cord-022526-j9kg00qf 2031 8 administers administer VBZ cord-022526-j9kg00qf 2031 9 medications medication NNS cord-022526-j9kg00qf 2031 10 such such JJ cord-022526-j9kg00qf 2031 11 as as IN cord-022526-j9kg00qf 2031 12 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 2031 13 antibiotics antibiotic NNS cord-022526-j9kg00qf 2031 14 , , , cord-022526-j9kg00qf 2031 15 which which WDT cord-022526-j9kg00qf 2031 16 share share VBP cord-022526-j9kg00qf 2031 17 a a DT cord-022526-j9kg00qf 2031 18 similar similar JJ cord-022526-j9kg00qf 2031 19 spectrum spectrum NN cord-022526-j9kg00qf 2031 20 of of IN cord-022526-j9kg00qf 2031 21 potential potential JJ cord-022526-j9kg00qf 2031 22 side side NN cord-022526-j9kg00qf 2031 23 effects effect NNS cord-022526-j9kg00qf 2031 24 , , , cord-022526-j9kg00qf 2031 25 concurrently concurrently RB cord-022526-j9kg00qf 2031 26 . . . cord-022526-j9kg00qf 2032 1 Azotemic Azotemic NNP cord-022526-j9kg00qf 2032 2 neonates neonate NNS cord-022526-j9kg00qf 2032 3 have have VBP cord-022526-j9kg00qf 2032 4 been be VBN cord-022526-j9kg00qf 2032 5 reported report VBN cord-022526-j9kg00qf 2032 6 to to TO cord-022526-j9kg00qf 2032 7 be be VB cord-022526-j9kg00qf 2032 8 more more RBR cord-022526-j9kg00qf 2032 9 susceptible susceptible JJ cord-022526-j9kg00qf 2032 10 to to IN cord-022526-j9kg00qf 2032 11 the the DT cord-022526-j9kg00qf 2032 12 nephrotoxic nephrotoxic JJ cord-022526-j9kg00qf 2032 13 effects effect NNS cord-022526-j9kg00qf 2032 14 of of IN cord-022526-j9kg00qf 2032 15 polymyxin polymyxin NN cord-022526-j9kg00qf 2032 16 B b NN cord-022526-j9kg00qf 2032 17 than than IN cord-022526-j9kg00qf 2032 18 adult adult NN cord-022526-j9kg00qf 2032 19 horses horse NNS cord-022526-j9kg00qf 2032 20 . . . cord-022526-j9kg00qf 2033 1 124 124 CD cord-022526-j9kg00qf 2034 1 In in IN cord-022526-j9kg00qf 2034 2 an an DT cord-022526-j9kg00qf 2034 3 attempt attempt NN cord-022526-j9kg00qf 2034 4 to to TO cord-022526-j9kg00qf 2034 5 decrease decrease VB cord-022526-j9kg00qf 2034 6 the the DT cord-022526-j9kg00qf 2034 7 risk risk NN cord-022526-j9kg00qf 2034 8 for for IN cord-022526-j9kg00qf 2034 9 adverse adverse JJ cord-022526-j9kg00qf 2034 10 effects effect NNS cord-022526-j9kg00qf 2034 11 while while IN cord-022526-j9kg00qf 2034 12 preserving preserve VBG cord-022526-j9kg00qf 2034 13 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2034 14 - - HYPH cord-022526-j9kg00qf 2034 15 neutralizing neutralize VBG cord-022526-j9kg00qf 2034 16 ability ability NN cord-022526-j9kg00qf 2034 17 , , , cord-022526-j9kg00qf 2034 18 a a DT cord-022526-j9kg00qf 2034 19 conjugate conjugate NN cord-022526-j9kg00qf 2034 20 of of IN cord-022526-j9kg00qf 2034 21 polymyxin polymyxin NN cord-022526-j9kg00qf 2034 22 B B NNP cord-022526-j9kg00qf 2034 23 with with IN cord-022526-j9kg00qf 2034 24 dextran dextran NN cord-022526-j9kg00qf 2034 25 has have VBZ cord-022526-j9kg00qf 2034 26 been be VBN cord-022526-j9kg00qf 2034 27 developed develop VBN cord-022526-j9kg00qf 2034 28 . . . cord-022526-j9kg00qf 2035 1 127 127 CD cord-022526-j9kg00qf 2036 1 In in IN cord-022526-j9kg00qf 2036 2 conjugated conjugated JJ cord-022526-j9kg00qf 2036 3 form form NN cord-022526-j9kg00qf 2036 4 , , , cord-022526-j9kg00qf 2036 5 polymyxin polymyxin NN cord-022526-j9kg00qf 2036 6 B B NNP cord-022526-j9kg00qf 2036 7 is be VBZ cord-022526-j9kg00qf 2036 8 prevented prevent VBN cord-022526-j9kg00qf 2036 9 from from IN cord-022526-j9kg00qf 2036 10 extravasation extravasation NN cord-022526-j9kg00qf 2036 11 into into IN cord-022526-j9kg00qf 2036 12 tissues tissue NNS cord-022526-j9kg00qf 2036 13 , , , cord-022526-j9kg00qf 2036 14 where where WRB cord-022526-j9kg00qf 2036 15 it -PRON- PRP cord-022526-j9kg00qf 2036 16 exerts exert VBZ cord-022526-j9kg00qf 2036 17 toxic toxic JJ cord-022526-j9kg00qf 2036 18 effects effect NNS cord-022526-j9kg00qf 2036 19 by by IN cord-022526-j9kg00qf 2036 20 interaction interaction NN cord-022526-j9kg00qf 2036 21 with with IN cord-022526-j9kg00qf 2036 22 cell cell NN cord-022526-j9kg00qf 2036 23 membranes membrane NNS cord-022526-j9kg00qf 2036 24 . . . cord-022526-j9kg00qf 2037 1 In in IN cord-022526-j9kg00qf 2037 2 addition addition NN cord-022526-j9kg00qf 2037 3 , , , cord-022526-j9kg00qf 2037 4 conjugation conjugation NN cord-022526-j9kg00qf 2037 5 increases increase VBZ cord-022526-j9kg00qf 2037 6 the the DT cord-022526-j9kg00qf 2037 7 residence residence NN cord-022526-j9kg00qf 2037 8 time time NN cord-022526-j9kg00qf 2037 9 of of IN cord-022526-j9kg00qf 2037 10 polymyxin polymyxin NNP cord-022526-j9kg00qf 2037 11 B B NNP cord-022526-j9kg00qf 2037 12 in in IN cord-022526-j9kg00qf 2037 13 the the DT cord-022526-j9kg00qf 2037 14 circulation circulation NN cord-022526-j9kg00qf 2037 15 and and CC cord-022526-j9kg00qf 2037 16 therefore therefore RB cord-022526-j9kg00qf 2037 17 should should MD cord-022526-j9kg00qf 2037 18 prolong prolong VB cord-022526-j9kg00qf 2037 19 the the DT cord-022526-j9kg00qf 2037 20 antiendotoxic antiendotoxic JJ cord-022526-j9kg00qf 2037 21 effect effect NN cord-022526-j9kg00qf 2037 22 . . . cord-022526-j9kg00qf 2038 1 The the DT cord-022526-j9kg00qf 2038 2 polymyxin polymyxin NN cord-022526-j9kg00qf 2038 3 B b NN cord-022526-j9kg00qf 2038 4 - - HYPH cord-022526-j9kg00qf 2038 5 dextran dextran NN cord-022526-j9kg00qf 2038 6 combination combination NN cord-022526-j9kg00qf 2038 7 was be VBD cord-022526-j9kg00qf 2038 8 evaluated evaluate VBN cord-022526-j9kg00qf 2038 9 at at IN cord-022526-j9kg00qf 2038 10 a a DT cord-022526-j9kg00qf 2038 11 total total JJ cord-022526-j9kg00qf 2038 12 dose dose NN cord-022526-j9kg00qf 2038 13 of of IN cord-022526-j9kg00qf 2038 14 5 5 CD cord-022526-j9kg00qf 2038 15 mg mg NNP cord-022526-j9kg00qf 2038 16 / / SYM cord-022526-j9kg00qf 2038 17 kg kg NNP cord-022526-j9kg00qf 2038 18 body body NN cord-022526-j9kg00qf 2038 19 mass mass NN cord-022526-j9kg00qf 2038 20 of of IN cord-022526-j9kg00qf 2038 21 polymyxin polymyxin NNP cord-022526-j9kg00qf 2038 22 B B NNP cord-022526-j9kg00qf 2038 23 in in IN cord-022526-j9kg00qf 2038 24 6.6 6.6 CD cord-022526-j9kg00qf 2038 25 g g NN cord-022526-j9kg00qf 2038 26 / / SYM cord-022526-j9kg00qf 2038 27 kg kg NN cord-022526-j9kg00qf 2038 28 body body NN cord-022526-j9kg00qf 2038 29 mass mass NN cord-022526-j9kg00qf 2038 30 dextran dextran NN cord-022526-j9kg00qf 2038 31 given give VBN cord-022526-j9kg00qf 2038 32 15 15 CD cord-022526-j9kg00qf 2038 33 minutes minute NNS cord-022526-j9kg00qf 2038 34 before before IN cord-022526-j9kg00qf 2038 35 administration administration NN cord-022526-j9kg00qf 2038 36 of of IN cord-022526-j9kg00qf 2038 37 endotoxin endotoxin NN cord-022526-j9kg00qf 2038 38 in in IN cord-022526-j9kg00qf 2038 39 horses horse NNS cord-022526-j9kg00qf 2038 40 . . . cord-022526-j9kg00qf 2039 1 128 128 CD cord-022526-j9kg00qf 2039 2 Treatment Treatment NNP cord-022526-j9kg00qf 2039 3 was be VBD cord-022526-j9kg00qf 2039 4 found find VBN cord-022526-j9kg00qf 2039 5 to to TO cord-022526-j9kg00qf 2039 6 block block VB cord-022526-j9kg00qf 2039 7 the the DT cord-022526-j9kg00qf 2039 8 development development NN cord-022526-j9kg00qf 2039 9 of of IN cord-022526-j9kg00qf 2039 10 tachycardia tachycardia NN cord-022526-j9kg00qf 2039 11 , , , cord-022526-j9kg00qf 2039 12 tachypnea tachypnea NNP cord-022526-j9kg00qf 2039 13 , , , cord-022526-j9kg00qf 2039 14 fever fever NN cord-022526-j9kg00qf 2039 15 , , , cord-022526-j9kg00qf 2039 16 and and CC cord-022526-j9kg00qf 2039 17 neutropenia neutropenia NN cord-022526-j9kg00qf 2039 18 completely completely RB cord-022526-j9kg00qf 2039 19 and and CC cord-022526-j9kg00qf 2039 20 to to TO cord-022526-j9kg00qf 2039 21 prevent prevent VB cord-022526-j9kg00qf 2039 22 increases increase NNS cord-022526-j9kg00qf 2039 23 in in IN cord-022526-j9kg00qf 2039 24 serum serum NN cord-022526-j9kg00qf 2039 25 concentrations concentration NNS cord-022526-j9kg00qf 2039 26 of of IN cord-022526-j9kg00qf 2039 27 TNF TNF NNP cord-022526-j9kg00qf 2039 28 , , , cord-022526-j9kg00qf 2039 29 IL-6 IL-6 NNP cord-022526-j9kg00qf 2039 30 , , , cord-022526-j9kg00qf 2039 31 TXB TXB NNP cord-022526-j9kg00qf 2039 32 2 2 CD cord-022526-j9kg00qf 2039 33 ( ( -LRB- cord-022526-j9kg00qf 2039 34 a a DT cord-022526-j9kg00qf 2039 35 TXA TXA NNP cord-022526-j9kg00qf 2039 36 2 2 CD cord-022526-j9kg00qf 2039 37 metabolite metabolite NN cord-022526-j9kg00qf 2039 38 ) ) -RRB- cord-022526-j9kg00qf 2039 39 , , , cord-022526-j9kg00qf 2039 40 and and CC cord-022526-j9kg00qf 2039 41 the the DT cord-022526-j9kg00qf 2039 42 prostacyclin prostacyclin NNP cord-022526-j9kg00qf 2039 43 metabolite metabolite NNP cord-022526-j9kg00qf 2039 44 6-keto 6-keto NNP cord-022526-j9kg00qf 2039 45 - - HYPH cord-022526-j9kg00qf 2039 46 PGF PGF NNP cord-022526-j9kg00qf 2039 47 1α 1α CD cord-022526-j9kg00qf 2039 48 . . . cord-022526-j9kg00qf 2040 1 Although although IN cord-022526-j9kg00qf 2040 2 mild mild JJ cord-022526-j9kg00qf 2040 3 adverse adverse JJ cord-022526-j9kg00qf 2040 4 effects effect NNS cord-022526-j9kg00qf 2040 5 in in IN cord-022526-j9kg00qf 2040 6 the the DT cord-022526-j9kg00qf 2040 7 form form NN cord-022526-j9kg00qf 2040 8 of of IN cord-022526-j9kg00qf 2040 9 tachypnea tachypnea NNP cord-022526-j9kg00qf 2040 10 , , , cord-022526-j9kg00qf 2040 11 sweating sweating NN cord-022526-j9kg00qf 2040 12 , , , cord-022526-j9kg00qf 2040 13 and and CC cord-022526-j9kg00qf 2040 14 increased increase VBD cord-022526-j9kg00qf 2040 15 systolic systolic JJ cord-022526-j9kg00qf 2040 16 blood blood NN cord-022526-j9kg00qf 2040 17 pressure pressure NN cord-022526-j9kg00qf 2040 18 were be VBD cord-022526-j9kg00qf 2040 19 observed observe VBN cord-022526-j9kg00qf 2040 20 , , , cord-022526-j9kg00qf 2040 21 these these DT cord-022526-j9kg00qf 2040 22 were be VBD cord-022526-j9kg00qf 2040 23 transient transient JJ cord-022526-j9kg00qf 2040 24 and and CC cord-022526-j9kg00qf 2040 25 could could MD cord-022526-j9kg00qf 2040 26 be be VB cord-022526-j9kg00qf 2040 27 prevented prevent VBN cord-022526-j9kg00qf 2040 28 by by IN cord-022526-j9kg00qf 2040 29 pretreatment pretreatment NN cord-022526-j9kg00qf 2040 30 with with IN cord-022526-j9kg00qf 2040 31 ketoprofen ketoprofen NNP cord-022526-j9kg00qf 2040 32 . . . cord-022526-j9kg00qf 2041 1 The the DT cord-022526-j9kg00qf 2041 2 polymyxin polymyxin NN cord-022526-j9kg00qf 2041 3 B b NN cord-022526-j9kg00qf 2041 4 - - HYPH cord-022526-j9kg00qf 2041 5 dextran dextran NN cord-022526-j9kg00qf 2041 6 combination combination NN cord-022526-j9kg00qf 2041 7 is be VBZ cord-022526-j9kg00qf 2041 8 not not RB cord-022526-j9kg00qf 2041 9 commercially commercially RB cord-022526-j9kg00qf 2041 10 available available JJ cord-022526-j9kg00qf 2041 11 at at IN cord-022526-j9kg00qf 2041 12 this this DT cord-022526-j9kg00qf 2041 13 time time NN cord-022526-j9kg00qf 2041 14 . . . cord-022526-j9kg00qf 2042 1 Natural natural JJ cord-022526-j9kg00qf 2042 2 endotoxin endotoxin NN cord-022526-j9kg00qf 2042 3 - - HYPH cord-022526-j9kg00qf 2042 4 binding bind VBG cord-022526-j9kg00qf 2042 5 proteins protein NNS cord-022526-j9kg00qf 2042 6 such such JJ cord-022526-j9kg00qf 2042 7 as as IN cord-022526-j9kg00qf 2042 8 LBP LBP NNP cord-022526-j9kg00qf 2042 9 , , , cord-022526-j9kg00qf 2042 10 lipoproteins lipoprotein NNS cord-022526-j9kg00qf 2042 11 , , , cord-022526-j9kg00qf 2042 12 and and CC cord-022526-j9kg00qf 2042 13 sCD14 scd14 NN cord-022526-j9kg00qf 2042 14 have have VBP cord-022526-j9kg00qf 2042 15 been be VBN cord-022526-j9kg00qf 2042 16 evaluated evaluate VBN cord-022526-j9kg00qf 2042 17 experimentally experimentally RB cord-022526-j9kg00qf 2042 18 . . . cord-022526-j9kg00qf 2043 1 Results result NNS cord-022526-j9kg00qf 2043 2 of of IN cord-022526-j9kg00qf 2043 3 these these DT cord-022526-j9kg00qf 2043 4 studies study NNS cord-022526-j9kg00qf 2043 5 are be VBP cord-022526-j9kg00qf 2043 6 controversial controversial JJ cord-022526-j9kg00qf 2043 7 , , , cord-022526-j9kg00qf 2043 8 and and CC cord-022526-j9kg00qf 2043 9 detrimental detrimental JJ cord-022526-j9kg00qf 2043 10 effects effect NNS cord-022526-j9kg00qf 2043 11 occurred occur VBD cord-022526-j9kg00qf 2043 12 in in IN cord-022526-j9kg00qf 2043 13 some some DT cord-022526-j9kg00qf 2043 14 cases case NNS cord-022526-j9kg00qf 2043 15 . . . cord-022526-j9kg00qf 2044 1 129 129 CD cord-022526-j9kg00qf 2044 2 A a DT cord-022526-j9kg00qf 2044 3 protein protein NN cord-022526-j9kg00qf 2044 4 receiving receive VBG cord-022526-j9kg00qf 2044 5 much much JJ cord-022526-j9kg00qf 2044 6 attention attention NN cord-022526-j9kg00qf 2044 7 regarding regard VBG cord-022526-j9kg00qf 2044 8 potential potential JJ cord-022526-j9kg00qf 2044 9 therapeutic therapeutic JJ cord-022526-j9kg00qf 2044 10 efficacy efficacy NN cord-022526-j9kg00qf 2044 11 is be VBZ cord-022526-j9kg00qf 2044 12 the the DT cord-022526-j9kg00qf 2044 13 bactericidal bactericidal JJ cord-022526-j9kg00qf 2044 14 permeability permeability NN cord-022526-j9kg00qf 2044 15 - - HYPH cord-022526-j9kg00qf 2044 16 increasing increase VBG cord-022526-j9kg00qf 2044 17 protein protein NN cord-022526-j9kg00qf 2044 18 ( ( -LRB- cord-022526-j9kg00qf 2044 19 BPI BPI NNP cord-022526-j9kg00qf 2044 20 ) ) -RRB- cord-022526-j9kg00qf 2044 21 . . . cord-022526-j9kg00qf 2045 1 This this DT cord-022526-j9kg00qf 2045 2 protein protein NN cord-022526-j9kg00qf 2045 3 is be VBZ cord-022526-j9kg00qf 2045 4 structurally structurally RB cord-022526-j9kg00qf 2045 5 similar similar JJ cord-022526-j9kg00qf 2045 6 to to IN cord-022526-j9kg00qf 2045 7 LBP LBP NNP cord-022526-j9kg00qf 2045 8 but but CC cord-022526-j9kg00qf 2045 9 is be VBZ cord-022526-j9kg00qf 2045 10 expressed express VBN cord-022526-j9kg00qf 2045 11 exclusively exclusively RB cord-022526-j9kg00qf 2045 12 in in IN cord-022526-j9kg00qf 2045 13 myeloid myeloid JJ cord-022526-j9kg00qf 2045 14 precursors precursor NNS cord-022526-j9kg00qf 2045 15 of of IN cord-022526-j9kg00qf 2045 16 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 2045 17 leukocytes leukocyte NNS cord-022526-j9kg00qf 2045 18 . . . cord-022526-j9kg00qf 2046 1 130 130 CD cord-022526-j9kg00qf 2046 2 BPI BPI NNP cord-022526-j9kg00qf 2046 3 is be VBZ cord-022526-j9kg00qf 2046 4 stored store VBN cord-022526-j9kg00qf 2046 5 in in IN cord-022526-j9kg00qf 2046 6 primary primary JJ cord-022526-j9kg00qf 2046 7 granules granule NNS cord-022526-j9kg00qf 2046 8 of of IN cord-022526-j9kg00qf 2046 9 mature mature JJ cord-022526-j9kg00qf 2046 10 neutrophils neutrophil NNS cord-022526-j9kg00qf 2046 11 and and CC cord-022526-j9kg00qf 2046 12 during during IN cord-022526-j9kg00qf 2046 13 inflammation inflammation NN cord-022526-j9kg00qf 2046 14 is be VBZ cord-022526-j9kg00qf 2046 15 expressed express VBN cord-022526-j9kg00qf 2046 16 on on IN cord-022526-j9kg00qf 2046 17 their -PRON- PRP$ cord-022526-j9kg00qf 2046 18 cell cell NN cord-022526-j9kg00qf 2046 19 membranes membrane NNS cord-022526-j9kg00qf 2046 20 and and CC cord-022526-j9kg00qf 2046 21 secreted secrete VBN cord-022526-j9kg00qf 2046 22 into into IN cord-022526-j9kg00qf 2046 23 the the DT cord-022526-j9kg00qf 2046 24 extracellular extracellular JJ cord-022526-j9kg00qf 2046 25 environment environment NN cord-022526-j9kg00qf 2046 26 . . . cord-022526-j9kg00qf 2047 1 131 131 CD cord-022526-j9kg00qf 2048 1 BPI BPI NNP cord-022526-j9kg00qf 2048 2 has have VBZ cord-022526-j9kg00qf 2048 3 an an DT cord-022526-j9kg00qf 2048 4 even even RB cord-022526-j9kg00qf 2048 5 higher high JJR cord-022526-j9kg00qf 2048 6 affinity affinity NN cord-022526-j9kg00qf 2048 7 for for IN cord-022526-j9kg00qf 2048 8 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2048 9 than than IN cord-022526-j9kg00qf 2048 10 LBP LBP NNP cord-022526-j9kg00qf 2048 11 132 132 CD cord-022526-j9kg00qf 2048 12 and and CC cord-022526-j9kg00qf 2048 13 shows show VBZ cord-022526-j9kg00qf 2048 14 antibacterial antibacterial JJ cord-022526-j9kg00qf 2048 15 activity activity NN cord-022526-j9kg00qf 2048 16 specific specific JJ cord-022526-j9kg00qf 2048 17 for for IN cord-022526-j9kg00qf 2048 18 gram gram NN cord-022526-j9kg00qf 2048 19 - - HYPH cord-022526-j9kg00qf 2048 20 negative negative JJ cord-022526-j9kg00qf 2048 21 bacteria bacteria NNS cord-022526-j9kg00qf 2048 22 . . . cord-022526-j9kg00qf 2049 1 65 65 CD cord-022526-j9kg00qf 2049 2 Binding binding NN cord-022526-j9kg00qf 2049 3 of of IN cord-022526-j9kg00qf 2049 4 BPI BPI NNP cord-022526-j9kg00qf 2049 5 to to IN cord-022526-j9kg00qf 2049 6 the the DT cord-022526-j9kg00qf 2049 7 gram gram NN cord-022526-j9kg00qf 2049 8 - - HYPH cord-022526-j9kg00qf 2049 9 negative negative JJ cord-022526-j9kg00qf 2049 10 bacterial bacterial JJ cord-022526-j9kg00qf 2049 11 membrane membrane NN cord-022526-j9kg00qf 2049 12 results result NNS cord-022526-j9kg00qf 2049 13 in in IN cord-022526-j9kg00qf 2049 14 growth growth NN cord-022526-j9kg00qf 2049 15 arrest arrest NN cord-022526-j9kg00qf 2049 16 and and CC cord-022526-j9kg00qf 2049 17 is be VBZ cord-022526-j9kg00qf 2049 18 an an DT cord-022526-j9kg00qf 2049 19 important important JJ cord-022526-j9kg00qf 2049 20 factor factor NN cord-022526-j9kg00qf 2049 21 in in IN cord-022526-j9kg00qf 2049 22 the the DT cord-022526-j9kg00qf 2049 23 antibacterial antibacterial JJ cord-022526-j9kg00qf 2049 24 activity activity NN cord-022526-j9kg00qf 2049 25 of of IN cord-022526-j9kg00qf 2049 26 intact intact JJ cord-022526-j9kg00qf 2049 27 neutrophils neutrophil NNS cord-022526-j9kg00qf 2049 28 . . . cord-022526-j9kg00qf 2050 1 Furthermore furthermore RB cord-022526-j9kg00qf 2050 2 , , , cord-022526-j9kg00qf 2050 3 BPI BPI NNP cord-022526-j9kg00qf 2050 4 binding binding NN cord-022526-j9kg00qf 2050 5 disrupts disrupt VBZ cord-022526-j9kg00qf 2050 6 normal normal JJ cord-022526-j9kg00qf 2050 7 membrane membrane NN cord-022526-j9kg00qf 2050 8 organization organization NN cord-022526-j9kg00qf 2050 9 and and CC cord-022526-j9kg00qf 2050 10 makes make VBZ cord-022526-j9kg00qf 2050 11 bacteria bacteria NNS cord-022526-j9kg00qf 2050 12 more more RBR cord-022526-j9kg00qf 2050 13 susceptible susceptible JJ cord-022526-j9kg00qf 2050 14 to to IN cord-022526-j9kg00qf 2050 15 hydrophobic hydrophobic JJ cord-022526-j9kg00qf 2050 16 substances substance NNS cord-022526-j9kg00qf 2050 17 , , , cord-022526-j9kg00qf 2050 18 including include VBG cord-022526-j9kg00qf 2050 19 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 2050 20 . . . cord-022526-j9kg00qf 2051 1 133 133 CD cord-022526-j9kg00qf 2052 1 Experimentally experimentally RB cord-022526-j9kg00qf 2052 2 , , , cord-022526-j9kg00qf 2052 3 recombinant recombinant JJ cord-022526-j9kg00qf 2052 4 BPI BPI NNP cord-022526-j9kg00qf 2052 5 has have VBZ cord-022526-j9kg00qf 2052 6 been be VBN cord-022526-j9kg00qf 2052 7 shown show VBN cord-022526-j9kg00qf 2052 8 to to TO cord-022526-j9kg00qf 2052 9 protect protect VB cord-022526-j9kg00qf 2052 10 against against IN cord-022526-j9kg00qf 2052 11 the the DT cord-022526-j9kg00qf 2052 12 toxic toxic JJ cord-022526-j9kg00qf 2052 13 and and CC cord-022526-j9kg00qf 2052 14 lethal lethal JJ cord-022526-j9kg00qf 2052 15 effects effect NNS cord-022526-j9kg00qf 2052 16 of of IN cord-022526-j9kg00qf 2052 17 isolated isolate VBN cord-022526-j9kg00qf 2052 18 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2052 19 and and CC cord-022526-j9kg00qf 2052 20 intact intact JJ cord-022526-j9kg00qf 2052 21 gram gram NN cord-022526-j9kg00qf 2052 22 - - HYPH cord-022526-j9kg00qf 2052 23 negative negative JJ cord-022526-j9kg00qf 2052 24 bacteria bacteria NNS cord-022526-j9kg00qf 2052 25 , , , cord-022526-j9kg00qf 2052 26 and and CC cord-022526-j9kg00qf 2052 27 clinical clinical JJ cord-022526-j9kg00qf 2052 28 trials trial NNS cord-022526-j9kg00qf 2052 29 in in IN cord-022526-j9kg00qf 2052 30 human human JJ cord-022526-j9kg00qf 2052 31 patients patient NNS cord-022526-j9kg00qf 2052 32 show show VBP cord-022526-j9kg00qf 2052 33 promising promising JJ cord-022526-j9kg00qf 2052 34 results result NNS cord-022526-j9kg00qf 2052 35 concerning concern VBG cord-022526-j9kg00qf 2052 36 its -PRON- PRP$ cord-022526-j9kg00qf 2052 37 therapeutic therapeutic JJ cord-022526-j9kg00qf 2052 38 use use NN cord-022526-j9kg00qf 2052 39 . . . cord-022526-j9kg00qf 2053 1 134 134 CD cord-022526-j9kg00qf 2054 1 The the DT cord-022526-j9kg00qf 2054 2 biology biology NN cord-022526-j9kg00qf 2054 3 and and CC cord-022526-j9kg00qf 2054 4 potential potential JJ cord-022526-j9kg00qf 2054 5 use use NN cord-022526-j9kg00qf 2054 6 of of IN cord-022526-j9kg00qf 2054 7 BPI BPI NNP cord-022526-j9kg00qf 2054 8 in in IN cord-022526-j9kg00qf 2054 9 horses horse NNS cord-022526-j9kg00qf 2054 10 has have VBZ cord-022526-j9kg00qf 2054 11 not not RB cord-022526-j9kg00qf 2054 12 been be VBN cord-022526-j9kg00qf 2054 13 evaluated evaluate VBN cord-022526-j9kg00qf 2054 14 . . . cord-022526-j9kg00qf 2055 1 Treatments treatment NNS cord-022526-j9kg00qf 2055 2 aimed aim VBN cord-022526-j9kg00qf 2055 3 at at IN cord-022526-j9kg00qf 2055 4 inhibiting inhibit VBG cord-022526-j9kg00qf 2055 5 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2055 6 interaction interaction NN cord-022526-j9kg00qf 2055 7 with with IN cord-022526-j9kg00qf 2055 8 cells cell NNS cord-022526-j9kg00qf 2055 9 or or CC cord-022526-j9kg00qf 2055 10 turning turn VBG cord-022526-j9kg00qf 2055 11 off off RP cord-022526-j9kg00qf 2055 12 intracellular intracellular JJ cord-022526-j9kg00qf 2055 13 signaling signal VBG cord-022526-j9kg00qf 2055 14 pathways pathway NNS cord-022526-j9kg00qf 2055 15 are be VBP cord-022526-j9kg00qf 2055 16 under under IN cord-022526-j9kg00qf 2055 17 investigation investigation NN cord-022526-j9kg00qf 2055 18 . . . cord-022526-j9kg00qf 2056 1 Nontoxic nontoxic JJ cord-022526-j9kg00qf 2056 2 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2056 3 or or CC cord-022526-j9kg00qf 2056 4 lipid lipid NN cord-022526-j9kg00qf 2056 5 A a DT cord-022526-j9kg00qf 2056 6 structures structure NNS cord-022526-j9kg00qf 2056 7 can can MD cord-022526-j9kg00qf 2056 8 act act VB cord-022526-j9kg00qf 2056 9 as as IN cord-022526-j9kg00qf 2056 10 endotoxin endotoxin NN cord-022526-j9kg00qf 2056 11 antagonists antagonist NNS cord-022526-j9kg00qf 2056 12 , , , cord-022526-j9kg00qf 2056 13 if if IN cord-022526-j9kg00qf 2056 14 they -PRON- PRP cord-022526-j9kg00qf 2056 15 competitively competitively RB cord-022526-j9kg00qf 2056 16 inhibit inhibit VBP cord-022526-j9kg00qf 2056 17 binding bind VBG cord-022526-j9kg00qf 2056 18 to to IN cord-022526-j9kg00qf 2056 19 LBP LBP NNP cord-022526-j9kg00qf 2056 20 or or CC cord-022526-j9kg00qf 2056 21 cellular cellular JJ cord-022526-j9kg00qf 2056 22 receptors receptor NNS cord-022526-j9kg00qf 2056 23 or or CC cord-022526-j9kg00qf 2056 24 inhibit inhibit VB cord-022526-j9kg00qf 2056 25 cellular cellular JJ cord-022526-j9kg00qf 2056 26 activation activation NN cord-022526-j9kg00qf 2056 27 by by IN cord-022526-j9kg00qf 2056 28 other other JJ cord-022526-j9kg00qf 2056 29 mechanisms mechanism NNS cord-022526-j9kg00qf 2056 30 . . . cord-022526-j9kg00qf 2057 1 Of of IN cord-022526-j9kg00qf 2057 2 the the DT cord-022526-j9kg00qf 2057 3 potential potential JJ cord-022526-j9kg00qf 2057 4 antagonists antagonist NNS cord-022526-j9kg00qf 2057 5 that that WDT cord-022526-j9kg00qf 2057 6 have have VBP cord-022526-j9kg00qf 2057 7 been be VBN cord-022526-j9kg00qf 2057 8 evaluated evaluate VBN cord-022526-j9kg00qf 2057 9 experimentally experimentally RB cord-022526-j9kg00qf 2057 10 , , , cord-022526-j9kg00qf 2057 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2057 12 and and CC cord-022526-j9kg00qf 2057 13 lipid lipid NN cord-022526-j9kg00qf 2057 14 A a NN cord-022526-j9kg00qf 2057 15 from from IN cord-022526-j9kg00qf 2057 16 the the DT cord-022526-j9kg00qf 2057 17 phototrophic phototrophic JJ cord-022526-j9kg00qf 2057 18 bacterium bacterium NN cord-022526-j9kg00qf 2057 19 Rhodobacter Rhodobacter NNP cord-022526-j9kg00qf 2057 20 sphaeroides sphaeroide NNS cord-022526-j9kg00qf 2057 21 , , , cord-022526-j9kg00qf 2057 22 and and CC cord-022526-j9kg00qf 2057 23 a a DT cord-022526-j9kg00qf 2057 24 synthetic synthetic JJ cord-022526-j9kg00qf 2057 25 compound compound NN cord-022526-j9kg00qf 2057 26 ( ( -LRB- cord-022526-j9kg00qf 2057 27 E5531 e5531 NN cord-022526-j9kg00qf 2057 28 ) ) -RRB- cord-022526-j9kg00qf 2057 29 the the DT cord-022526-j9kg00qf 2057 30 structure structure NN cord-022526-j9kg00qf 2057 31 of of IN cord-022526-j9kg00qf 2057 32 which which WDT cord-022526-j9kg00qf 2057 33 is be VBZ cord-022526-j9kg00qf 2057 34 based base VBN cord-022526-j9kg00qf 2057 35 on on IN cord-022526-j9kg00qf 2057 36 R. R. NNP cord-022526-j9kg00qf 2057 37 sphaeroides sphaeroide NNS cord-022526-j9kg00qf 2057 38 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2057 39 , , , cord-022526-j9kg00qf 2057 40 have have VBP cord-022526-j9kg00qf 2057 41 been be VBN cord-022526-j9kg00qf 2057 42 most most RBS cord-022526-j9kg00qf 2057 43 promising promising JJ cord-022526-j9kg00qf 2057 44 . . . cord-022526-j9kg00qf 2058 1 [ [ -LRB- cord-022526-j9kg00qf 2058 2 135 135 CD cord-022526-j9kg00qf 2058 3 ] ] -RRB- cord-022526-j9kg00qf 2058 4 [ [ -LRB- cord-022526-j9kg00qf 2058 5 136 136 CD cord-022526-j9kg00qf 2058 6 ] ] -RRB- cord-022526-j9kg00qf 2058 7 [ [ -LRB- cord-022526-j9kg00qf 2058 8 137 137 CD cord-022526-j9kg00qf 2058 9 ] ] -RRB- cord-022526-j9kg00qf 2059 1 [ [ -LRB- cord-022526-j9kg00qf 2059 2 138 138 CD cord-022526-j9kg00qf 2059 3 ] ] -RRB- cord-022526-j9kg00qf 2060 1 [ [ -LRB- cord-022526-j9kg00qf 2060 2 139 139 CD cord-022526-j9kg00qf 2060 3 ] ] -RRB- cord-022526-j9kg00qf 2061 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 2061 2 , , , cord-022526-j9kg00qf 2061 3 species species NN cord-022526-j9kg00qf 2061 4 differences difference NNS cord-022526-j9kg00qf 2061 5 exist exist VBP cord-022526-j9kg00qf 2061 6 regarding regard VBG cord-022526-j9kg00qf 2061 7 cellular cellular JJ cord-022526-j9kg00qf 2061 8 response response NN cord-022526-j9kg00qf 2061 9 to to IN cord-022526-j9kg00qf 2061 10 these these DT cord-022526-j9kg00qf 2061 11 structures structure NNS cord-022526-j9kg00qf 2061 12 , , , cord-022526-j9kg00qf 2061 13 and and CC cord-022526-j9kg00qf 2061 14 R. R. NNP cord-022526-j9kg00qf 2061 15 sphaeroides sphaeroide NNS cord-022526-j9kg00qf 2062 1 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2062 2 acts act VBZ cord-022526-j9kg00qf 2062 3 as as IN cord-022526-j9kg00qf 2062 4 a a DT cord-022526-j9kg00qf 2062 5 potent potent JJ cord-022526-j9kg00qf 2062 6 inducer inducer NN cord-022526-j9kg00qf 2062 7 of of IN cord-022526-j9kg00qf 2062 8 cytokine cytokine JJ cord-022526-j9kg00qf 2062 9 expression expression NN cord-022526-j9kg00qf 2062 10 in in IN cord-022526-j9kg00qf 2062 11 equine equine JJ cord-022526-j9kg00qf 2062 12 cells cell NNS cord-022526-j9kg00qf 2062 13 . . . cord-022526-j9kg00qf 2063 1 140 140 CD cord-022526-j9kg00qf 2064 1 Based base VBN cord-022526-j9kg00qf 2064 2 on on IN cord-022526-j9kg00qf 2064 3 results result NNS cord-022526-j9kg00qf 2064 4 of of IN cord-022526-j9kg00qf 2064 5 receptor receptor NN cord-022526-j9kg00qf 2064 6 transfection transfection NN cord-022526-j9kg00qf 2064 7 studies study NNS cord-022526-j9kg00qf 2064 8 in in IN cord-022526-j9kg00qf 2064 9 other other JJ cord-022526-j9kg00qf 2064 10 species specie NNS cord-022526-j9kg00qf 2064 11 , , , cord-022526-j9kg00qf 2064 12 141,142 141,142 CD cord-022526-j9kg00qf 2064 13 TLR4 TLR4 NNP cord-022526-j9kg00qf 2064 14 is be VBZ cord-022526-j9kg00qf 2064 15 likely likely RB cord-022526-j9kg00qf 2064 16 responsible responsible JJ cord-022526-j9kg00qf 2064 17 for for IN cord-022526-j9kg00qf 2064 18 this this DT cord-022526-j9kg00qf 2064 19 phenotypic phenotypic JJ cord-022526-j9kg00qf 2064 20 variation variation NN cord-022526-j9kg00qf 2064 21 . . . cord-022526-j9kg00qf 2065 1 Additional additional JJ cord-022526-j9kg00qf 2065 2 compounds compound NNS cord-022526-j9kg00qf 2065 3 including include VBG cord-022526-j9kg00qf 2065 4 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2065 5 derived derive VBN cord-022526-j9kg00qf 2065 6 from from IN cord-022526-j9kg00qf 2065 7 nitrogen nitrogen NN cord-022526-j9kg00qf 2065 8 - - HYPH cord-022526-j9kg00qf 2065 9 fixing fix VBG cord-022526-j9kg00qf 2065 10 plant plant NN cord-022526-j9kg00qf 2065 11 bacteria bacteria NNS cord-022526-j9kg00qf 2065 12 of of IN cord-022526-j9kg00qf 2065 13 the the DT cord-022526-j9kg00qf 2065 14 species specie NNS cord-022526-j9kg00qf 2065 15 Rhizobium rhizobium NN cord-022526-j9kg00qf 2065 16 are be VBP cord-022526-j9kg00qf 2065 17 being be VBG cord-022526-j9kg00qf 2065 18 evaluated evaluate VBN cord-022526-j9kg00qf 2065 19 to to TO cord-022526-j9kg00qf 2065 20 reveal reveal VB cord-022526-j9kg00qf 2065 21 further further JJ cord-022526-j9kg00qf 2065 22 insight insight NN cord-022526-j9kg00qf 2065 23 into into IN cord-022526-j9kg00qf 2065 24 structural structural JJ cord-022526-j9kg00qf 2065 25 requirements requirement NNS cord-022526-j9kg00qf 2065 26 for for IN cord-022526-j9kg00qf 2065 27 endotoxin endotoxin NN cord-022526-j9kg00qf 2065 28 antagonists antagonist NNS cord-022526-j9kg00qf 2065 29 in in IN cord-022526-j9kg00qf 2065 30 horses horse NNS cord-022526-j9kg00qf 2065 31 . . . cord-022526-j9kg00qf 2066 1 Nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 2066 2 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2066 3 drugs drug NNS cord-022526-j9kg00qf 2066 4 ( ( -LRB- cord-022526-j9kg00qf 2066 5 NSAIDs nsaid NNS cord-022526-j9kg00qf 2066 6 ) ) -RRB- cord-022526-j9kg00qf 2066 7 are be VBP cord-022526-j9kg00qf 2066 8 probably probably RB cord-022526-j9kg00qf 2066 9 the the DT cord-022526-j9kg00qf 2066 10 most most RBS cord-022526-j9kg00qf 2066 11 commonly commonly RB cord-022526-j9kg00qf 2066 12 used use VBN cord-022526-j9kg00qf 2066 13 drugs drug NNS cord-022526-j9kg00qf 2066 14 to to TO cord-022526-j9kg00qf 2066 15 treat treat VB cord-022526-j9kg00qf 2066 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2066 17 . . . cord-022526-j9kg00qf 2067 1 The the DT cord-022526-j9kg00qf 2067 2 rationale rationale NN cord-022526-j9kg00qf 2067 3 for for IN cord-022526-j9kg00qf 2067 4 their -PRON- PRP$ cord-022526-j9kg00qf 2067 5 use use NN cord-022526-j9kg00qf 2067 6 is be VBZ cord-022526-j9kg00qf 2067 7 inhibition inhibition NN cord-022526-j9kg00qf 2067 8 of of IN cord-022526-j9kg00qf 2067 9 prostaglandin prostaglandin NN cord-022526-j9kg00qf 2067 10 endoperoxide endoperoxide NN cord-022526-j9kg00qf 2067 11 H h NN cord-022526-j9kg00qf 2067 12 synthase synthase NN cord-022526-j9kg00qf 2067 13 , , , cord-022526-j9kg00qf 2067 14 that that RB cord-022526-j9kg00qf 2067 15 is is RB cord-022526-j9kg00qf 2067 16 , , , cord-022526-j9kg00qf 2067 17 COX COX NNP cord-022526-j9kg00qf 2067 18 , , , cord-022526-j9kg00qf 2067 19 and and CC cord-022526-j9kg00qf 2067 20 thereby thereby RB cord-022526-j9kg00qf 2067 21 inhibition inhibition NN cord-022526-j9kg00qf 2067 22 of of IN cord-022526-j9kg00qf 2067 23 prostanoid prostanoid JJ cord-022526-j9kg00qf 2067 24 production production NN cord-022526-j9kg00qf 2067 25 ( ( -LRB- cord-022526-j9kg00qf 2067 26 see see VB cord-022526-j9kg00qf 2067 27 Figure figure NN cord-022526-j9kg00qf 2067 28 13 13 CD cord-022526-j9kg00qf 2067 29 .7 .7 CD cord-022526-j9kg00qf 2067 30 - - HYPH cord-022526-j9kg00qf 2067 31 5 5 CD cord-022526-j9kg00qf 2067 32 ) ) -RRB- cord-022526-j9kg00qf 2067 33 . . . cord-022526-j9kg00qf 2068 1 Additional additional JJ cord-022526-j9kg00qf 2068 2 beneficial beneficial JJ cord-022526-j9kg00qf 2068 3 effects effect NNS cord-022526-j9kg00qf 2068 4 may may MD cord-022526-j9kg00qf 2068 5 include include VB cord-022526-j9kg00qf 2068 6 scavenging scavenging NN cord-022526-j9kg00qf 2068 7 of of IN cord-022526-j9kg00qf 2068 8 oxygen oxygen NN cord-022526-j9kg00qf 2068 9 - - HYPH cord-022526-j9kg00qf 2068 10 derived derive VBN cord-022526-j9kg00qf 2068 11 free free JJ cord-022526-j9kg00qf 2068 12 radicals radical NNS cord-022526-j9kg00qf 2068 13 and and CC cord-022526-j9kg00qf 2068 14 iron iron NN cord-022526-j9kg00qf 2068 15 chelation chelation NN cord-022526-j9kg00qf 2068 16 ; ; : cord-022526-j9kg00qf 2068 17 however however RB cord-022526-j9kg00qf 2068 18 , , , cord-022526-j9kg00qf 2068 19 side side NN cord-022526-j9kg00qf 2068 20 effects effect NNS cord-022526-j9kg00qf 2068 21 may may MD cord-022526-j9kg00qf 2068 22 occur occur VB cord-022526-j9kg00qf 2068 23 at at IN cord-022526-j9kg00qf 2068 24 dosages dosage NNS cord-022526-j9kg00qf 2068 25 required require VBN cord-022526-j9kg00qf 2068 26 to to TO cord-022526-j9kg00qf 2068 27 achieve achieve VB cord-022526-j9kg00qf 2068 28 these these DT cord-022526-j9kg00qf 2068 29 effects effect NNS cord-022526-j9kg00qf 2068 30 . . . cord-022526-j9kg00qf 2069 1 143 143 CD cord-022526-j9kg00qf 2070 1 Prostanoids prostanoid NNS cord-022526-j9kg00qf 2070 2 have have VBP cord-022526-j9kg00qf 2070 3 been be VBN cord-022526-j9kg00qf 2070 4 identified identify VBN cord-022526-j9kg00qf 2070 5 as as IN cord-022526-j9kg00qf 2070 6 important important JJ cord-022526-j9kg00qf 2070 7 mediators mediator NNS cord-022526-j9kg00qf 2070 8 in in IN cord-022526-j9kg00qf 2070 9 the the DT cord-022526-j9kg00qf 2070 10 inflammatory inflammatory JJ cord-022526-j9kg00qf 2070 11 response response NN cord-022526-j9kg00qf 2070 12 in in IN cord-022526-j9kg00qf 2070 13 a a DT cord-022526-j9kg00qf 2070 14 number number NN cord-022526-j9kg00qf 2070 15 of of IN cord-022526-j9kg00qf 2070 16 studies study NNS cord-022526-j9kg00qf 2070 17 , , , cord-022526-j9kg00qf 2070 18 and and CC cord-022526-j9kg00qf 2070 19 inhibition inhibition NN cord-022526-j9kg00qf 2070 20 of of IN cord-022526-j9kg00qf 2070 21 their -PRON- PRP$ cord-022526-j9kg00qf 2070 22 synthesis synthesis NN cord-022526-j9kg00qf 2070 23 is be VBZ cord-022526-j9kg00qf 2070 24 associated associate VBN cord-022526-j9kg00qf 2070 25 with with IN cord-022526-j9kg00qf 2070 26 beneficial beneficial JJ cord-022526-j9kg00qf 2070 27 effects effect NNS cord-022526-j9kg00qf 2070 28 . . . cord-022526-j9kg00qf 2071 1 Two two CD cord-022526-j9kg00qf 2071 2 COX COX NNP cord-022526-j9kg00qf 2071 3 isoforms isoform NNS cord-022526-j9kg00qf 2071 4 are be VBP cord-022526-j9kg00qf 2071 5 recognized recognize VBN cord-022526-j9kg00qf 2071 6 : : : cord-022526-j9kg00qf 2071 7 constitutively constitutively RB cord-022526-j9kg00qf 2071 8 expressed express VBN cord-022526-j9kg00qf 2071 9 COX-1 cox-1 JJ cord-022526-j9kg00qf 2071 10 and and CC cord-022526-j9kg00qf 2071 11 inducible inducible JJ cord-022526-j9kg00qf 2071 12 COX-2 COX-2 NNP cord-022526-j9kg00qf 2071 13 . . . cord-022526-j9kg00qf 2072 1 Upregulation Upregulation NNP cord-022526-j9kg00qf 2072 2 of of IN cord-022526-j9kg00qf 2072 3 COX-2 cox-2 JJ cord-022526-j9kg00qf 2072 4 expression expression NN cord-022526-j9kg00qf 2072 5 results result NNS cord-022526-j9kg00qf 2072 6 from from IN cord-022526-j9kg00qf 2072 7 various various JJ cord-022526-j9kg00qf 2072 8 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 2072 9 stimuli stimulus NNS cord-022526-j9kg00qf 2072 10 , , , cord-022526-j9kg00qf 2072 11 including include VBG cord-022526-j9kg00qf 2072 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2072 13 , , , cord-022526-j9kg00qf 2072 14 TNF TNF NNP cord-022526-j9kg00qf 2072 15 - - HYPH cord-022526-j9kg00qf 2072 16 α α NNP cord-022526-j9kg00qf 2072 17 , , , cord-022526-j9kg00qf 2072 18 and and CC cord-022526-j9kg00qf 2072 19 IL-1 IL-1 NNP cord-022526-j9kg00qf 2072 20 . . . cord-022526-j9kg00qf 2073 1 144 144 CD cord-022526-j9kg00qf 2074 1 Constitutively Constitutively NNP cord-022526-j9kg00qf 2074 2 expressed express VBD cord-022526-j9kg00qf 2074 3 COX COX NNP cord-022526-j9kg00qf 2074 4 products product NNS cord-022526-j9kg00qf 2074 5 are be VBP cord-022526-j9kg00qf 2074 6 likely likely RB cord-022526-j9kg00qf 2074 7 important important JJ cord-022526-j9kg00qf 2074 8 for for IN cord-022526-j9kg00qf 2074 9 maintenance maintenance NN cord-022526-j9kg00qf 2074 10 of of IN cord-022526-j9kg00qf 2074 11 homeostasis homeostasis NN cord-022526-j9kg00qf 2074 12 , , , cord-022526-j9kg00qf 2074 13 whereas whereas IN cord-022526-j9kg00qf 2074 14 increased increase VBN cord-022526-j9kg00qf 2074 15 production production NN cord-022526-j9kg00qf 2074 16 of of IN cord-022526-j9kg00qf 2074 17 prostanoids prostanoid NNS cord-022526-j9kg00qf 2074 18 by by IN cord-022526-j9kg00qf 2074 19 COX-2 COX-2 NNP cord-022526-j9kg00qf 2074 20 is be VBZ cord-022526-j9kg00qf 2074 21 thought think VBN cord-022526-j9kg00qf 2074 22 to to TO cord-022526-j9kg00qf 2074 23 be be VB cord-022526-j9kg00qf 2074 24 responsible responsible JJ cord-022526-j9kg00qf 2074 25 for for IN cord-022526-j9kg00qf 2074 26 detrimental detrimental JJ cord-022526-j9kg00qf 2074 27 effects effect NNS cord-022526-j9kg00qf 2074 28 during during IN cord-022526-j9kg00qf 2074 29 inflammation inflammation NN cord-022526-j9kg00qf 2074 30 and and CC cord-022526-j9kg00qf 2074 31 shock shock NN cord-022526-j9kg00qf 2074 32 . . . cord-022526-j9kg00qf 2075 1 Research research NN cord-022526-j9kg00qf 2075 2 has have VBZ cord-022526-j9kg00qf 2075 3 focused focus VBN cord-022526-j9kg00qf 2075 4 on on IN cord-022526-j9kg00qf 2075 5 the the DT cord-022526-j9kg00qf 2075 6 development development NN cord-022526-j9kg00qf 2075 7 of of IN cord-022526-j9kg00qf 2075 8 selective selective JJ cord-022526-j9kg00qf 2075 9 COX-2 cox-2 JJ cord-022526-j9kg00qf 2075 10 inhibitors inhibitor NNS cord-022526-j9kg00qf 2075 11 ; ; : cord-022526-j9kg00qf 2075 12 however however RB cord-022526-j9kg00qf 2075 13 , , , cord-022526-j9kg00qf 2075 14 none none NN cord-022526-j9kg00qf 2075 15 of of IN cord-022526-j9kg00qf 2075 16 these these DT cord-022526-j9kg00qf 2075 17 products product NNS cord-022526-j9kg00qf 2075 18 are be VBP cord-022526-j9kg00qf 2075 19 currently currently RB cord-022526-j9kg00qf 2075 20 available available JJ cord-022526-j9kg00qf 2075 21 for for IN cord-022526-j9kg00qf 2075 22 use use NN cord-022526-j9kg00qf 2075 23 in in IN cord-022526-j9kg00qf 2075 24 horses horse NNS cord-022526-j9kg00qf 2075 25 . . . cord-022526-j9kg00qf 2076 1 In in IN cord-022526-j9kg00qf 2076 2 horses horse NNS cord-022526-j9kg00qf 2076 3 the the DT cord-022526-j9kg00qf 2076 4 most most RBS cord-022526-j9kg00qf 2076 5 commonly commonly RB cord-022526-j9kg00qf 2076 6 used use VBN cord-022526-j9kg00qf 2076 7 NSAID NSAID NNP cord-022526-j9kg00qf 2076 8 to to TO cord-022526-j9kg00qf 2076 9 treat treat VB cord-022526-j9kg00qf 2076 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2076 11 is be VBZ cord-022526-j9kg00qf 2076 12 flunixin flunixin NNP cord-022526-j9kg00qf 2076 13 meglumine meglumine NNP cord-022526-j9kg00qf 2076 14 . . . cord-022526-j9kg00qf 2077 1 Beneficial beneficial JJ cord-022526-j9kg00qf 2077 2 effects effect NNS cord-022526-j9kg00qf 2077 3 of of IN cord-022526-j9kg00qf 2077 4 flunixin flunixin NNP cord-022526-j9kg00qf 2077 5 meglumine meglumine NNP cord-022526-j9kg00qf 2077 6 have have VBP cord-022526-j9kg00qf 2077 7 been be VBN cord-022526-j9kg00qf 2077 8 described describe VBN cord-022526-j9kg00qf 2077 9 in in IN cord-022526-j9kg00qf 2077 10 experimental experimental JJ cord-022526-j9kg00qf 2077 11 models model NNS cord-022526-j9kg00qf 2077 12 of of IN cord-022526-j9kg00qf 2077 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2077 14 [ [ -LRB- cord-022526-j9kg00qf 2077 15 145 145 CD cord-022526-j9kg00qf 2077 16 ] ] -RRB- cord-022526-j9kg00qf 2077 17 [ [ -LRB- cord-022526-j9kg00qf 2077 18 146 146 CD cord-022526-j9kg00qf 2077 19 ] ] -RRB- cord-022526-j9kg00qf 2077 20 [ [ -LRB- cord-022526-j9kg00qf 2077 21 147 147 CD cord-022526-j9kg00qf 2077 22 ] ] -RRB- cord-022526-j9kg00qf 2077 23 and and CC cord-022526-j9kg00qf 2077 24 in in IN cord-022526-j9kg00qf 2077 25 clinical clinical JJ cord-022526-j9kg00qf 2077 26 cases case NNS cord-022526-j9kg00qf 2077 27 . . . cord-022526-j9kg00qf 2078 1 In in IN cord-022526-j9kg00qf 2078 2 equine equine JJ cord-022526-j9kg00qf 2078 3 colic colic NN cord-022526-j9kg00qf 2078 4 patients patient NNS cord-022526-j9kg00qf 2078 5 , , , cord-022526-j9kg00qf 2078 6 treatment treatment NN cord-022526-j9kg00qf 2078 7 with with IN cord-022526-j9kg00qf 2078 8 flunixin flunixin NNP cord-022526-j9kg00qf 2078 9 meglumine meglumine NNP cord-022526-j9kg00qf 2078 10 before before IN cord-022526-j9kg00qf 2078 11 exploratory exploratory JJ cord-022526-j9kg00qf 2078 12 surgery surgery NN cord-022526-j9kg00qf 2078 13 resulted result VBD cord-022526-j9kg00qf 2078 14 in in IN cord-022526-j9kg00qf 2078 15 reduced reduce VBN cord-022526-j9kg00qf 2078 16 plasma plasma NN cord-022526-j9kg00qf 2078 17 concentrations concentration NNS cord-022526-j9kg00qf 2078 18 of of IN cord-022526-j9kg00qf 2078 19 TXB TXB NNP cord-022526-j9kg00qf 2078 20 2 2 CD cord-022526-j9kg00qf 2078 21 and and CC cord-022526-j9kg00qf 2078 22 PGE PGE NNP cord-022526-j9kg00qf 2078 23 2 2 CD cord-022526-j9kg00qf 2078 24 and and CC cord-022526-j9kg00qf 2078 25 had have VBD cord-022526-j9kg00qf 2078 26 a a DT cord-022526-j9kg00qf 2078 27 favorable favorable JJ cord-022526-j9kg00qf 2078 28 effect effect NN cord-022526-j9kg00qf 2078 29 on on IN cord-022526-j9kg00qf 2078 30 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 2078 31 parameters parameter NNS cord-022526-j9kg00qf 2078 32 . . . cord-022526-j9kg00qf 2079 1 148 148 CD cord-022526-j9kg00qf 2079 2 Flunixin Flunixin NNP cord-022526-j9kg00qf 2079 3 meglumine meglumine NN cord-022526-j9kg00qf 2079 4 was be VBD cord-022526-j9kg00qf 2079 5 shown show VBN cord-022526-j9kg00qf 2079 6 further further RB cord-022526-j9kg00qf 2079 7 to to TO cord-022526-j9kg00qf 2079 8 maintain maintain VB cord-022526-j9kg00qf 2079 9 cardiac cardiac JJ cord-022526-j9kg00qf 2079 10 output output NN cord-022526-j9kg00qf 2079 11 and and CC cord-022526-j9kg00qf 2079 12 systemic systemic JJ cord-022526-j9kg00qf 2079 13 arterial arterial JJ cord-022526-j9kg00qf 2079 14 blood blood NN cord-022526-j9kg00qf 2079 15 pressure pressure NN cord-022526-j9kg00qf 2079 16 , , , cord-022526-j9kg00qf 2079 17 improve improve VB cord-022526-j9kg00qf 2079 18 blood blood NN cord-022526-j9kg00qf 2079 19 flow flow NN cord-022526-j9kg00qf 2079 20 to to IN cord-022526-j9kg00qf 2079 21 vital vital JJ cord-022526-j9kg00qf 2079 22 organs organ NNS cord-022526-j9kg00qf 2079 23 , , , cord-022526-j9kg00qf 2079 24 reduce reduce VB cord-022526-j9kg00qf 2079 25 pulmonary pulmonary JJ cord-022526-j9kg00qf 2079 26 endothelial endothelial JJ cord-022526-j9kg00qf 2079 27 damage damage NN cord-022526-j9kg00qf 2079 28 , , , cord-022526-j9kg00qf 2079 29 and and CC cord-022526-j9kg00qf 2079 30 improve improve VB cord-022526-j9kg00qf 2079 31 survival survival NN cord-022526-j9kg00qf 2079 32 on on IN cord-022526-j9kg00qf 2079 33 endotoxin endotoxin NN cord-022526-j9kg00qf 2079 34 challenge challenge NN cord-022526-j9kg00qf 2079 35 . . . cord-022526-j9kg00qf 2080 1 [ [ -LRB- cord-022526-j9kg00qf 2080 2 149 149 CD cord-022526-j9kg00qf 2080 3 ] ] -RRB- cord-022526-j9kg00qf 2080 4 [ [ -LRB- cord-022526-j9kg00qf 2080 5 150 150 CD cord-022526-j9kg00qf 2080 6 ] ] -RRB- cord-022526-j9kg00qf 2080 7 [ [ -LRB- cord-022526-j9kg00qf 2080 8 151 151 CD cord-022526-j9kg00qf 2080 9 ] ] -RRB- cord-022526-j9kg00qf 2081 1 [ [ -LRB- cord-022526-j9kg00qf 2081 2 152 152 CD cord-022526-j9kg00qf 2081 3 ] ] -RRB- cord-022526-j9kg00qf 2081 4 NSAID NSAID NNP cord-022526-j9kg00qf 2081 5 use use NN cord-022526-j9kg00qf 2081 6 in in IN cord-022526-j9kg00qf 2081 7 horses horse NNS cord-022526-j9kg00qf 2081 8 carries carry VBZ cord-022526-j9kg00qf 2081 9 the the DT cord-022526-j9kg00qf 2081 10 risk risk NN cord-022526-j9kg00qf 2081 11 of of IN cord-022526-j9kg00qf 2081 12 side side NN cord-022526-j9kg00qf 2081 13 effects effect NNS cord-022526-j9kg00qf 2081 14 , , , cord-022526-j9kg00qf 2081 15 most most RBS cord-022526-j9kg00qf 2081 16 importantly importantly RB cord-022526-j9kg00qf 2081 17 the the DT cord-022526-j9kg00qf 2081 18 development development NN cord-022526-j9kg00qf 2081 19 of of IN cord-022526-j9kg00qf 2081 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2081 21 ulceration ulceration NN cord-022526-j9kg00qf 2081 22 and and CC cord-022526-j9kg00qf 2081 23 renal renal JJ cord-022526-j9kg00qf 2081 24 papillary papillary JJ cord-022526-j9kg00qf 2081 25 necrosis necrosis NN cord-022526-j9kg00qf 2081 26 ( ( -LRB- cord-022526-j9kg00qf 2081 27 renal renal JJ cord-022526-j9kg00qf 2081 28 crest crest NNP cord-022526-j9kg00qf 2081 29 necrosis necrosis NN cord-022526-j9kg00qf 2081 30 ) ) -RRB- cord-022526-j9kg00qf 2081 31 . . . cord-022526-j9kg00qf 2082 1 In in IN cord-022526-j9kg00qf 2082 2 a a DT cord-022526-j9kg00qf 2082 3 study study NN cord-022526-j9kg00qf 2082 4 comparing compare VBG cord-022526-j9kg00qf 2082 5 the the DT cord-022526-j9kg00qf 2082 6 side side JJ cord-022526-j9kg00qf 2082 7 effects effect NNS cord-022526-j9kg00qf 2082 8 of of IN cord-022526-j9kg00qf 2082 9 flunixin flunixin NNP cord-022526-j9kg00qf 2082 10 meglumine meglumine NNP cord-022526-j9kg00qf 2082 11 ( ( -LRB- cord-022526-j9kg00qf 2082 12 1.1 1.1 CD cord-022526-j9kg00qf 2082 13 mg mg NNP cord-022526-j9kg00qf 2082 14 / / SYM cord-022526-j9kg00qf 2082 15 kg kg NNP cord-022526-j9kg00qf 2082 16 body body NN cord-022526-j9kg00qf 2082 17 mass mass NN cord-022526-j9kg00qf 2082 18 ) ) -RRB- cord-022526-j9kg00qf 2082 19 , , , cord-022526-j9kg00qf 2082 20 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 2082 21 ( ( -LRB- cord-022526-j9kg00qf 2082 22 4.4 4.4 CD cord-022526-j9kg00qf 2082 23 mg mg NNP cord-022526-j9kg00qf 2082 24 / / SYM cord-022526-j9kg00qf 2082 25 kg kg NNP cord-022526-j9kg00qf 2082 26 body body NN cord-022526-j9kg00qf 2082 27 mass mass NN cord-022526-j9kg00qf 2082 28 ) ) -RRB- cord-022526-j9kg00qf 2082 29 , , , cord-022526-j9kg00qf 2082 30 and and CC cord-022526-j9kg00qf 2082 31 ketoprofen ketoprofen NNP cord-022526-j9kg00qf 2082 32 ( ( -LRB- cord-022526-j9kg00qf 2082 33 2.2 2.2 CD cord-022526-j9kg00qf 2082 34 mg mg NNP cord-022526-j9kg00qf 2082 35 / / SYM cord-022526-j9kg00qf 2082 36 kg kg NNP cord-022526-j9kg00qf 2082 37 body body NN cord-022526-j9kg00qf 2082 38 mass mass NN cord-022526-j9kg00qf 2082 39 ) ) -RRB- cord-022526-j9kg00qf 2082 40 given give VBN cord-022526-j9kg00qf 2082 41 3 3 CD cord-022526-j9kg00qf 2082 42 times time NNS cord-022526-j9kg00qf 2082 43 daily daily RB cord-022526-j9kg00qf 2082 44 for for IN cord-022526-j9kg00qf 2082 45 12 12 CD cord-022526-j9kg00qf 2082 46 days day NNS cord-022526-j9kg00qf 2082 47 , , , cord-022526-j9kg00qf 2082 48 lesions lesion NNS cord-022526-j9kg00qf 2082 49 of of IN cord-022526-j9kg00qf 2082 50 the the DT cord-022526-j9kg00qf 2082 51 gastric gastric JJ cord-022526-j9kg00qf 2082 52 glandular glandular JJ cord-022526-j9kg00qf 2082 53 mucosa mucosa NN cord-022526-j9kg00qf 2082 54 occurred occur VBD cord-022526-j9kg00qf 2082 55 most most RBS cord-022526-j9kg00qf 2082 56 commonly commonly RB cord-022526-j9kg00qf 2082 57 . . . cord-022526-j9kg00qf 2083 1 Phenylbutazone Phenylbutazone NNP cord-022526-j9kg00qf 2083 2 resulted result VBD cord-022526-j9kg00qf 2083 3 in in IN cord-022526-j9kg00qf 2083 4 the the DT cord-022526-j9kg00qf 2083 5 most most RBS cord-022526-j9kg00qf 2083 6 severe severe JJ cord-022526-j9kg00qf 2083 7 side side NN cord-022526-j9kg00qf 2083 8 effects effect NNS cord-022526-j9kg00qf 2083 9 , , , cord-022526-j9kg00qf 2083 10 which which WDT cord-022526-j9kg00qf 2083 11 included include VBD cord-022526-j9kg00qf 2083 12 small small JJ cord-022526-j9kg00qf 2083 13 intestinal intestinal JJ cord-022526-j9kg00qf 2083 14 edema edema NN cord-022526-j9kg00qf 2083 15 , , , cord-022526-j9kg00qf 2083 16 erosions erosion NNS cord-022526-j9kg00qf 2083 17 , , , cord-022526-j9kg00qf 2083 18 and and CC cord-022526-j9kg00qf 2083 19 ulcers ulcer NNS cord-022526-j9kg00qf 2083 20 in in IN cord-022526-j9kg00qf 2083 21 the the DT cord-022526-j9kg00qf 2083 22 large large JJ cord-022526-j9kg00qf 2083 23 colon colon NN cord-022526-j9kg00qf 2083 24 and and CC cord-022526-j9kg00qf 2083 25 decreased decrease VBD cord-022526-j9kg00qf 2083 26 serum serum NN cord-022526-j9kg00qf 2083 27 albumin albumin NN cord-022526-j9kg00qf 2083 28 concentration concentration NN cord-022526-j9kg00qf 2083 29 . . . cord-022526-j9kg00qf 2084 1 Renal renal JJ cord-022526-j9kg00qf 2084 2 crest crest NN cord-022526-j9kg00qf 2084 3 necrosis necrosis NN cord-022526-j9kg00qf 2084 4 occurred occur VBD cord-022526-j9kg00qf 2084 5 more more RBR cord-022526-j9kg00qf 2084 6 frequently frequently RB cord-022526-j9kg00qf 2084 7 in in IN cord-022526-j9kg00qf 2084 8 horses horse NNS cord-022526-j9kg00qf 2084 9 treated treat VBN cord-022526-j9kg00qf 2084 10 with with IN cord-022526-j9kg00qf 2084 11 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 2084 12 but but CC cord-022526-j9kg00qf 2084 13 also also RB cord-022526-j9kg00qf 2084 14 occurred occur VBD cord-022526-j9kg00qf 2084 15 with with IN cord-022526-j9kg00qf 2084 16 flunixin flunixin NNP cord-022526-j9kg00qf 2084 17 meglumine meglumine NNP cord-022526-j9kg00qf 2084 18 treatment treatment NN cord-022526-j9kg00qf 2084 19 . . . cord-022526-j9kg00qf 2085 1 153 153 CD cord-022526-j9kg00qf 2086 1 Despite despite IN cord-022526-j9kg00qf 2086 2 the the DT cord-022526-j9kg00qf 2086 3 higher high JJR cord-022526-j9kg00qf 2086 4 risk risk NN cord-022526-j9kg00qf 2086 5 of of IN cord-022526-j9kg00qf 2086 6 side side NN cord-022526-j9kg00qf 2086 7 effects effect NNS cord-022526-j9kg00qf 2086 8 , , , cord-022526-j9kg00qf 2086 9 use use NN cord-022526-j9kg00qf 2086 10 of of IN cord-022526-j9kg00qf 2086 11 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 2086 12 has have VBZ cord-022526-j9kg00qf 2086 13 been be VBN cord-022526-j9kg00qf 2086 14 suggested suggest VBN cord-022526-j9kg00qf 2086 15 for for IN cord-022526-j9kg00qf 2086 16 certain certain JJ cord-022526-j9kg00qf 2086 17 cases case NNS cord-022526-j9kg00qf 2086 18 . . . cord-022526-j9kg00qf 2087 1 In in IN cord-022526-j9kg00qf 2087 2 colic colic NN cord-022526-j9kg00qf 2087 3 patients patient NNS cord-022526-j9kg00qf 2087 4 , , , cord-022526-j9kg00qf 2087 5 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 2087 6 may may MD cord-022526-j9kg00qf 2087 7 provide provide VB cord-022526-j9kg00qf 2087 8 analgesia analgesia NN cord-022526-j9kg00qf 2087 9 and and CC cord-022526-j9kg00qf 2087 10 ameliorate ameliorate VB cord-022526-j9kg00qf 2087 11 endotoxin endotoxin NN cord-022526-j9kg00qf 2087 12 - - HYPH cord-022526-j9kg00qf 2087 13 induced induce VBN cord-022526-j9kg00qf 2087 14 ileus ileus NN cord-022526-j9kg00qf 2087 15 without without IN cord-022526-j9kg00qf 2087 16 masking mask VBG cord-022526-j9kg00qf 2087 17 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 2087 18 effects effect NNS cord-022526-j9kg00qf 2087 19 of of IN cord-022526-j9kg00qf 2087 20 endotoxin endotoxin NN cord-022526-j9kg00qf 2087 21 , , , cord-022526-j9kg00qf 2087 22 which which WDT cord-022526-j9kg00qf 2087 23 are be VBP cord-022526-j9kg00qf 2087 24 used use VBN cord-022526-j9kg00qf 2087 25 to to TO cord-022526-j9kg00qf 2087 26 determine determine VB cord-022526-j9kg00qf 2087 27 the the DT cord-022526-j9kg00qf 2087 28 necessity necessity NN cord-022526-j9kg00qf 2087 29 of of IN cord-022526-j9kg00qf 2087 30 surgical surgical JJ cord-022526-j9kg00qf 2087 31 exploration exploration NN cord-022526-j9kg00qf 2087 32 . . . cord-022526-j9kg00qf 2088 1 154 154 CD cord-022526-j9kg00qf 2089 1 For for IN cord-022526-j9kg00qf 2089 2 similar similar JJ cord-022526-j9kg00qf 2089 3 reasons reason NNS cord-022526-j9kg00qf 2089 4 and and CC cord-022526-j9kg00qf 2089 5 to to TO cord-022526-j9kg00qf 2089 6 minimize minimize VB cord-022526-j9kg00qf 2089 7 side side NN cord-022526-j9kg00qf 2089 8 effects effect NNS cord-022526-j9kg00qf 2089 9 a a DT cord-022526-j9kg00qf 2089 10 reduced reduced JJ cord-022526-j9kg00qf 2089 11 dose dose NN cord-022526-j9kg00qf 2089 12 of of IN cord-022526-j9kg00qf 2089 13 flunixin flunixin NNP cord-022526-j9kg00qf 2089 14 meglumine meglumine NNP cord-022526-j9kg00qf 2089 15 ( ( -LRB- cord-022526-j9kg00qf 2089 16 0.25 0.25 CD cord-022526-j9kg00qf 2089 17 mg mg NNP cord-022526-j9kg00qf 2089 18 / / SYM cord-022526-j9kg00qf 2089 19 kg kg NNP cord-022526-j9kg00qf 2089 20 body body NN cord-022526-j9kg00qf 2089 21 mass mass NN cord-022526-j9kg00qf 2089 22 ) ) -RRB- cord-022526-j9kg00qf 2089 23 has have VBZ cord-022526-j9kg00qf 2089 24 been be VBN cord-022526-j9kg00qf 2089 25 suggested suggest VBN cord-022526-j9kg00qf 2089 26 and and CC cord-022526-j9kg00qf 2089 27 is be VBZ cord-022526-j9kg00qf 2089 28 used use VBN cord-022526-j9kg00qf 2089 29 widely widely RB cord-022526-j9kg00qf 2089 30 in in IN cord-022526-j9kg00qf 2089 31 horses horse NNS cord-022526-j9kg00qf 2089 32 . . . cord-022526-j9kg00qf 2090 1 155 155 CD cord-022526-j9kg00qf 2091 1 At at IN cord-022526-j9kg00qf 2091 2 this this DT cord-022526-j9kg00qf 2091 3 dosage dosage NN cord-022526-j9kg00qf 2091 4 , , , cord-022526-j9kg00qf 2091 5 flunixin flunixin NNP cord-022526-j9kg00qf 2091 6 meglumine meglumine NNP cord-022526-j9kg00qf 2091 7 was be VBD cord-022526-j9kg00qf 2091 8 shown show VBN cord-022526-j9kg00qf 2091 9 to to TO cord-022526-j9kg00qf 2091 10 inhibit inhibit VB cord-022526-j9kg00qf 2091 11 eicosanoid eicosanoid JJ cord-022526-j9kg00qf 2091 12 synthesis synthesis NN cord-022526-j9kg00qf 2091 13 efficiently efficiently RB cord-022526-j9kg00qf 2091 14 in in IN cord-022526-j9kg00qf 2091 15 an an DT cord-022526-j9kg00qf 2091 16 in in IN cord-022526-j9kg00qf 2091 17 vivo vivo NN cord-022526-j9kg00qf 2091 18 model model NN cord-022526-j9kg00qf 2091 19 of of IN cord-022526-j9kg00qf 2091 20 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2091 21 . . . cord-022526-j9kg00qf 2092 1 156 156 CD cord-022526-j9kg00qf 2092 2 Reduction reduction NN cord-022526-j9kg00qf 2092 3 of of IN cord-022526-j9kg00qf 2092 4 clinical clinical JJ cord-022526-j9kg00qf 2092 5 signs sign NNS cord-022526-j9kg00qf 2092 6 , , , cord-022526-j9kg00qf 2092 7 however however RB cord-022526-j9kg00qf 2092 8 , , , cord-022526-j9kg00qf 2092 9 was be VBD cord-022526-j9kg00qf 2092 10 dose dose RB cord-022526-j9kg00qf 2092 11 dependent dependent JJ cord-022526-j9kg00qf 2092 12 , , , cord-022526-j9kg00qf 2092 13 and and CC cord-022526-j9kg00qf 2092 14 therefore therefore RB cord-022526-j9kg00qf 2092 15 one one PRP cord-022526-j9kg00qf 2092 16 should should MD cord-022526-j9kg00qf 2092 17 choose choose VB cord-022526-j9kg00qf 2092 18 the the DT cord-022526-j9kg00qf 2092 19 appropriate appropriate JJ cord-022526-j9kg00qf 2092 20 dose dose NN cord-022526-j9kg00qf 2092 21 based base VBN cord-022526-j9kg00qf 2092 22 on on IN cord-022526-j9kg00qf 2092 23 the the DT cord-022526-j9kg00qf 2092 24 circumstances circumstance NNS cord-022526-j9kg00qf 2092 25 of of IN cord-022526-j9kg00qf 2092 26 each each DT cord-022526-j9kg00qf 2092 27 case case NN cord-022526-j9kg00qf 2092 28 . . . cord-022526-j9kg00qf 2093 1 Ketoprofen Ketoprofen NNP cord-022526-j9kg00qf 2093 2 has have VBZ cord-022526-j9kg00qf 2093 3 been be VBN cord-022526-j9kg00qf 2093 4 suggested suggest VBN cord-022526-j9kg00qf 2093 5 to to TO cord-022526-j9kg00qf 2093 6 have have VB cord-022526-j9kg00qf 2093 7 superior superior JJ cord-022526-j9kg00qf 2093 8 effects effect NNS cord-022526-j9kg00qf 2093 9 because because IN cord-022526-j9kg00qf 2093 10 of of IN cord-022526-j9kg00qf 2093 11 a a DT cord-022526-j9kg00qf 2093 12 proposed propose VBN cord-022526-j9kg00qf 2093 13 dual dual JJ cord-022526-j9kg00qf 2093 14 inhibitory inhibitory JJ cord-022526-j9kg00qf 2093 15 effect effect NN cord-022526-j9kg00qf 2093 16 on on IN cord-022526-j9kg00qf 2093 17 COX COX NNP cord-022526-j9kg00qf 2093 18 and and CC cord-022526-j9kg00qf 2093 19 lipoxygenase lipoxygenase NN cord-022526-j9kg00qf 2093 20 and and CC cord-022526-j9kg00qf 2093 21 may may MD cord-022526-j9kg00qf 2093 22 carry carry VB cord-022526-j9kg00qf 2093 23 a a DT cord-022526-j9kg00qf 2093 24 decreased decrease VBN cord-022526-j9kg00qf 2093 25 risk risk NN cord-022526-j9kg00qf 2093 26 of of IN cord-022526-j9kg00qf 2093 27 side side NN cord-022526-j9kg00qf 2093 28 effects effect NNS cord-022526-j9kg00qf 2093 29 compared compare VBN cord-022526-j9kg00qf 2093 30 with with IN cord-022526-j9kg00qf 2093 31 flunixin flunixin NNP cord-022526-j9kg00qf 2093 32 meglumine meglumine NNP cord-022526-j9kg00qf 2093 33 and and CC cord-022526-j9kg00qf 2093 34 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 2093 35 . . . cord-022526-j9kg00qf 2094 1 A a DT cord-022526-j9kg00qf 2094 2 comparison comparison NN cord-022526-j9kg00qf 2094 3 of of IN cord-022526-j9kg00qf 2094 4 cytokine cytokine NN cord-022526-j9kg00qf 2094 5 and and CC cord-022526-j9kg00qf 2094 6 eicosanoid eicosanoid JJ cord-022526-j9kg00qf 2094 7 production production NN cord-022526-j9kg00qf 2094 8 by by IN cord-022526-j9kg00qf 2094 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2094 10 - - HYPH cord-022526-j9kg00qf 2094 11 stimulated stimulate VBN cord-022526-j9kg00qf 2094 12 isolated isolate VBN cord-022526-j9kg00qf 2094 13 monocytes monocyte NNS cord-022526-j9kg00qf 2094 14 in in IN cord-022526-j9kg00qf 2094 15 vitro vitro FW cord-022526-j9kg00qf 2094 16 , , , cord-022526-j9kg00qf 2094 17 however however RB cord-022526-j9kg00qf 2094 18 , , , cord-022526-j9kg00qf 2094 19 showed show VBD cord-022526-j9kg00qf 2094 20 no no DT cord-022526-j9kg00qf 2094 21 significant significant JJ cord-022526-j9kg00qf 2094 22 difference difference NN cord-022526-j9kg00qf 2094 23 between between IN cord-022526-j9kg00qf 2094 24 horses horse NNS cord-022526-j9kg00qf 2094 25 pretreated pretreate VBN cord-022526-j9kg00qf 2094 26 with with IN cord-022526-j9kg00qf 2094 27 flunixin flunixin NNP cord-022526-j9kg00qf 2094 28 meglumine meglumine NNP cord-022526-j9kg00qf 2094 29 ( ( -LRB- cord-022526-j9kg00qf 2094 30 1.1 1.1 CD cord-022526-j9kg00qf 2094 31 mg mg NNP cord-022526-j9kg00qf 2094 32 / / SYM cord-022526-j9kg00qf 2094 33 kg kg NNP cord-022526-j9kg00qf 2094 34 body body NN cord-022526-j9kg00qf 2094 35 mass mass NN cord-022526-j9kg00qf 2094 36 ) ) -RRB- cord-022526-j9kg00qf 2094 37 or or CC cord-022526-j9kg00qf 2094 38 ketoprofen ketoprofen NNP cord-022526-j9kg00qf 2094 39 ( ( -LRB- cord-022526-j9kg00qf 2094 40 2.2 2.2 CD cord-022526-j9kg00qf 2094 41 mg mg NNP cord-022526-j9kg00qf 2094 42 / / SYM cord-022526-j9kg00qf 2094 43 kg kg NNP cord-022526-j9kg00qf 2094 44 body body NN cord-022526-j9kg00qf 2094 45 mass mass NN cord-022526-j9kg00qf 2094 46 ) ) -RRB- cord-022526-j9kg00qf 2094 47 , , , cord-022526-j9kg00qf 2094 48 respectively respectively RB cord-022526-j9kg00qf 2094 49 . . . cord-022526-j9kg00qf 2095 1 157 157 CD cord-022526-j9kg00qf 2095 2 Eltenac Eltenac NNP cord-022526-j9kg00qf 2095 3 has have VBZ cord-022526-j9kg00qf 2095 4 been be VBN cord-022526-j9kg00qf 2095 5 evaluated evaluate VBN cord-022526-j9kg00qf 2095 6 in in IN cord-022526-j9kg00qf 2095 7 an an DT cord-022526-j9kg00qf 2095 8 experimental experimental JJ cord-022526-j9kg00qf 2095 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2095 10 model model NN cord-022526-j9kg00qf 2095 11 in in IN cord-022526-j9kg00qf 2095 12 horses horse NNS cord-022526-j9kg00qf 2095 13 . . . cord-022526-j9kg00qf 2096 1 158 158 CD cord-022526-j9kg00qf 2097 1 Given give VBN cord-022526-j9kg00qf 2097 2 15 15 CD cord-022526-j9kg00qf 2097 3 minutes minute NNS cord-022526-j9kg00qf 2097 4 before before IN cord-022526-j9kg00qf 2097 5 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2097 6 infusion infusion NN cord-022526-j9kg00qf 2097 7 , , , cord-022526-j9kg00qf 2097 8 eltenac eltenac NNP cord-022526-j9kg00qf 2097 9 at at IN cord-022526-j9kg00qf 2097 10 a a DT cord-022526-j9kg00qf 2097 11 dose dose NN cord-022526-j9kg00qf 2097 12 of of IN cord-022526-j9kg00qf 2098 1 0.5 0.5 CD cord-022526-j9kg00qf 2098 2 mg mg NNP cord-022526-j9kg00qf 2098 3 / / SYM cord-022526-j9kg00qf 2098 4 kg kg NNS cord-022526-j9kg00qf 2098 5 protected protect VBN cord-022526-j9kg00qf 2098 6 against against IN cord-022526-j9kg00qf 2098 7 changes change NNS cord-022526-j9kg00qf 2098 8 in in IN cord-022526-j9kg00qf 2098 9 clinical clinical JJ cord-022526-j9kg00qf 2098 10 , , , cord-022526-j9kg00qf 2098 11 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 2098 12 , , , cord-022526-j9kg00qf 2098 13 and and CC cord-022526-j9kg00qf 2098 14 hematologic hematologic JJ cord-022526-j9kg00qf 2098 15 parameters parameter NNS cord-022526-j9kg00qf 2098 16 and and CC cord-022526-j9kg00qf 2098 17 blunted blunt VBD cord-022526-j9kg00qf 2098 18 the the DT cord-022526-j9kg00qf 2098 19 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2098 20 - - HYPH cord-022526-j9kg00qf 2098 21 induced induce VBN cord-022526-j9kg00qf 2098 22 rise rise NN cord-022526-j9kg00qf 2098 23 in in IN cord-022526-j9kg00qf 2098 24 plasma plasma NN cord-022526-j9kg00qf 2098 25 cytokine cytokine NN cord-022526-j9kg00qf 2098 26 concentrations concentration NNS cord-022526-j9kg00qf 2098 27 in in IN cord-022526-j9kg00qf 2098 28 comparison comparison NN cord-022526-j9kg00qf 2098 29 with with IN cord-022526-j9kg00qf 2098 30 controls control NNS cord-022526-j9kg00qf 2098 31 . . . cord-022526-j9kg00qf 2099 1 Some some DT cord-022526-j9kg00qf 2099 2 parameters parameter NNS cord-022526-j9kg00qf 2099 3 , , , cord-022526-j9kg00qf 2099 4 however however RB cord-022526-j9kg00qf 2099 5 , , , cord-022526-j9kg00qf 2099 6 including include VBG cord-022526-j9kg00qf 2099 7 heart heart NN cord-022526-j9kg00qf 2099 8 rate rate NN cord-022526-j9kg00qf 2099 9 , , , cord-022526-j9kg00qf 2099 10 leukocyte leukocyte NN cord-022526-j9kg00qf 2099 11 count count NN cord-022526-j9kg00qf 2099 12 , , , cord-022526-j9kg00qf 2099 13 lactate lactate NN cord-022526-j9kg00qf 2099 14 concentration concentration NN cord-022526-j9kg00qf 2099 15 , , , cord-022526-j9kg00qf 2099 16 and and CC cord-022526-j9kg00qf 2099 17 plasma plasma NN cord-022526-j9kg00qf 2099 18 TNF TNF NNP cord-022526-j9kg00qf 2099 19 activity activity NN cord-022526-j9kg00qf 2099 20 , , , cord-022526-j9kg00qf 2099 21 were be VBD cord-022526-j9kg00qf 2099 22 not not RB cord-022526-j9kg00qf 2099 23 improved improve VBN cord-022526-j9kg00qf 2099 24 . . . cord-022526-j9kg00qf 2100 1 Ibuprofen Ibuprofen NNP cord-022526-j9kg00qf 2100 2 may may MD cord-022526-j9kg00qf 2100 3 have have VB cord-022526-j9kg00qf 2100 4 beneficial beneficial JJ cord-022526-j9kg00qf 2100 5 effects effect NNS cord-022526-j9kg00qf 2100 6 superior superior JJ cord-022526-j9kg00qf 2100 7 to to IN cord-022526-j9kg00qf 2100 8 the the DT cord-022526-j9kg00qf 2100 9 other other JJ cord-022526-j9kg00qf 2100 10 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 2100 11 , , , cord-022526-j9kg00qf 2100 12 because because IN cord-022526-j9kg00qf 2100 13 it -PRON- PRP cord-022526-j9kg00qf 2100 14 may may MD cord-022526-j9kg00qf 2100 15 be be VB cord-022526-j9kg00qf 2100 16 possible possible JJ cord-022526-j9kg00qf 2100 17 to to TO cord-022526-j9kg00qf 2100 18 achieve achieve VB cord-022526-j9kg00qf 2100 19 tissue tissue NN cord-022526-j9kg00qf 2100 20 concentrations concentration NNS cord-022526-j9kg00qf 2100 21 safely safely RB cord-022526-j9kg00qf 2100 22 that that WDT cord-022526-j9kg00qf 2100 23 allow allow VBP cord-022526-j9kg00qf 2100 24 iron iron NN cord-022526-j9kg00qf 2100 25 chelation chelation NN cord-022526-j9kg00qf 2100 26 to to TO cord-022526-j9kg00qf 2100 27 occur occur VB cord-022526-j9kg00qf 2100 28 . . . cord-022526-j9kg00qf 2101 1 According accord VBG cord-022526-j9kg00qf 2101 2 to to IN cord-022526-j9kg00qf 2101 3 a a DT cord-022526-j9kg00qf 2101 4 study study NN cord-022526-j9kg00qf 2101 5 in in IN cord-022526-j9kg00qf 2101 6 healthy healthy JJ cord-022526-j9kg00qf 2101 7 foals foal NNS cord-022526-j9kg00qf 2101 8 , , , cord-022526-j9kg00qf 2101 9 dosages dosage NNS cord-022526-j9kg00qf 2101 10 of of IN cord-022526-j9kg00qf 2101 11 ibuprofen ibuprofen NN cord-022526-j9kg00qf 2101 12 up up IN cord-022526-j9kg00qf 2101 13 to to TO cord-022526-j9kg00qf 2101 14 25 25 CD cord-022526-j9kg00qf 2101 15 mg mg NNP cord-022526-j9kg00qf 2101 16 / / SYM cord-022526-j9kg00qf 2101 17 kg kg NN cord-022526-j9kg00qf 2101 18 every every DT cord-022526-j9kg00qf 2101 19 8 8 CD cord-022526-j9kg00qf 2101 20 hours hour NNS cord-022526-j9kg00qf 2101 21 can can MD cord-022526-j9kg00qf 2101 22 be be VB cord-022526-j9kg00qf 2101 23 given give VBN cord-022526-j9kg00qf 2101 24 safely safely RB cord-022526-j9kg00qf 2101 25 for for IN cord-022526-j9kg00qf 2101 26 up up IN cord-022526-j9kg00qf 2101 27 to to TO cord-022526-j9kg00qf 2101 28 6 6 CD cord-022526-j9kg00qf 2101 29 days day NNS cord-022526-j9kg00qf 2101 30 . . . cord-022526-j9kg00qf 2102 1 143 143 CD cord-022526-j9kg00qf 2103 1 The the DT cord-022526-j9kg00qf 2103 2 use use NN cord-022526-j9kg00qf 2103 3 of of IN cord-022526-j9kg00qf 2103 4 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 2103 5 for for IN cord-022526-j9kg00qf 2103 6 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2103 7 therapy therapy NN cord-022526-j9kg00qf 2103 8 in in IN cord-022526-j9kg00qf 2103 9 sepsis sepsis NN cord-022526-j9kg00qf 2103 10 and and CC cord-022526-j9kg00qf 2103 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2103 12 has have VBZ cord-022526-j9kg00qf 2103 13 been be VBN cord-022526-j9kg00qf 2103 14 controversial controversial JJ cord-022526-j9kg00qf 2103 15 in in IN cord-022526-j9kg00qf 2103 16 human human JJ cord-022526-j9kg00qf 2103 17 and and CC cord-022526-j9kg00qf 2103 18 equine equine JJ cord-022526-j9kg00qf 2103 19 patients patient NNS cord-022526-j9kg00qf 2103 20 , , , cord-022526-j9kg00qf 2103 21 and and CC cord-022526-j9kg00qf 2103 22 beneficial beneficial JJ cord-022526-j9kg00qf 2103 23 effects effect NNS cord-022526-j9kg00qf 2103 24 superior superior JJ cord-022526-j9kg00qf 2103 25 to to IN cord-022526-j9kg00qf 2103 26 the the DT cord-022526-j9kg00qf 2103 27 ones one NNS cord-022526-j9kg00qf 2103 28 achieved achieve VBN cord-022526-j9kg00qf 2103 29 by by IN cord-022526-j9kg00qf 2103 30 NSAIDs nsaid NNS cord-022526-j9kg00qf 2103 31 have have VBP cord-022526-j9kg00qf 2103 32 not not RB cord-022526-j9kg00qf 2103 33 been be VBN cord-022526-j9kg00qf 2103 34 demonstrated demonstrate VBN cord-022526-j9kg00qf 2103 35 consistently consistently RB cord-022526-j9kg00qf 2103 36 overall overall RB cord-022526-j9kg00qf 2103 37 . . . cord-022526-j9kg00qf 2104 1 Corticosteroids corticosteroid NNS cord-022526-j9kg00qf 2104 2 inhibit inhibit VBP cord-022526-j9kg00qf 2104 3 the the DT cord-022526-j9kg00qf 2104 4 activity activity NN cord-022526-j9kg00qf 2104 5 of of IN cord-022526-j9kg00qf 2104 6 phospholipase phospholipase NN cord-022526-j9kg00qf 2104 7 A a DT cord-022526-j9kg00qf 2104 8 2 2 CD cord-022526-j9kg00qf 2104 9 and and CC cord-022526-j9kg00qf 2104 10 the the DT cord-022526-j9kg00qf 2104 11 release release NN cord-022526-j9kg00qf 2104 12 of of IN cord-022526-j9kg00qf 2104 13 arachidonic arachidonic JJ cord-022526-j9kg00qf 2104 14 acid acid NN cord-022526-j9kg00qf 2104 15 from from IN cord-022526-j9kg00qf 2104 16 cell cell NN cord-022526-j9kg00qf 2104 17 membrane membrane NN cord-022526-j9kg00qf 2104 18 phospholipids phospholipid NNS cord-022526-j9kg00qf 2104 19 , , , cord-022526-j9kg00qf 2104 20 as as RB cord-022526-j9kg00qf 2104 21 well well RB cord-022526-j9kg00qf 2104 22 as as IN cord-022526-j9kg00qf 2104 23 the the DT cord-022526-j9kg00qf 2104 24 production production NN cord-022526-j9kg00qf 2104 25 of of IN cord-022526-j9kg00qf 2104 26 TNF TNF NNP cord-022526-j9kg00qf 2104 27 , , , cord-022526-j9kg00qf 2104 28 IL-1 IL-1 NNP cord-022526-j9kg00qf 2104 29 , , , cord-022526-j9kg00qf 2104 30 and and CC cord-022526-j9kg00qf 2104 31 IL-6 IL-6 NNP cord-022526-j9kg00qf 2104 32 in in IN cord-022526-j9kg00qf 2104 33 response response NN cord-022526-j9kg00qf 2104 34 to to IN cord-022526-j9kg00qf 2104 35 a a DT cord-022526-j9kg00qf 2104 36 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2104 37 stimulus stimulus NN cord-022526-j9kg00qf 2104 38 . . . cord-022526-j9kg00qf 2105 1 Experimentally experimentally RB cord-022526-j9kg00qf 2105 2 , , , cord-022526-j9kg00qf 2105 3 beneficial beneficial JJ cord-022526-j9kg00qf 2105 4 effects effect NNS cord-022526-j9kg00qf 2105 5 of of IN cord-022526-j9kg00qf 2105 6 dexamethasone dexamethasone NN cord-022526-j9kg00qf 2105 7 in in IN cord-022526-j9kg00qf 2105 8 equine equine JJ cord-022526-j9kg00qf 2105 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2105 10 have have VBP cord-022526-j9kg00qf 2105 11 been be VBN cord-022526-j9kg00qf 2105 12 demonstrated demonstrate VBN cord-022526-j9kg00qf 2105 13 . . . cord-022526-j9kg00qf 2106 1 159 159 CD cord-022526-j9kg00qf 2106 2 , , , cord-022526-j9kg00qf 2106 3 160 160 CD cord-022526-j9kg00qf 2107 1 To to TO cord-022526-j9kg00qf 2107 2 inhibit inhibit VB cord-022526-j9kg00qf 2107 3 TNF TNF NNP cord-022526-j9kg00qf 2107 4 production production NN cord-022526-j9kg00qf 2107 5 by by IN cord-022526-j9kg00qf 2107 6 equine equine JJ cord-022526-j9kg00qf 2107 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 2107 8 macrophages macrophage NNS cord-022526-j9kg00qf 2107 9 , , , cord-022526-j9kg00qf 2107 10 however however RB cord-022526-j9kg00qf 2107 11 , , , cord-022526-j9kg00qf 2107 12 the the DT cord-022526-j9kg00qf 2107 13 required require VBN cord-022526-j9kg00qf 2107 14 concentration concentration NN cord-022526-j9kg00qf 2107 15 of of IN cord-022526-j9kg00qf 2107 16 dexamethasone dexamethasone NN cord-022526-j9kg00qf 2107 17 was be VBD cord-022526-j9kg00qf 2107 18 high high JJ cord-022526-j9kg00qf 2107 19 and and CC cord-022526-j9kg00qf 2107 20 corresponded correspond VBD cord-022526-j9kg00qf 2107 21 to to IN cord-022526-j9kg00qf 2107 22 an an DT cord-022526-j9kg00qf 2107 23 in in IN cord-022526-j9kg00qf 2107 24 vivo vivo NN cord-022526-j9kg00qf 2107 25 dosage dosage NN cord-022526-j9kg00qf 2107 26 ( ( -LRB- cord-022526-j9kg00qf 2107 27 approximately approximately RB cord-022526-j9kg00qf 2107 28 3 3 CD cord-022526-j9kg00qf 2107 29 mg mg NN cord-022526-j9kg00qf 2107 30 / / SYM cord-022526-j9kg00qf 2107 31 kg kg NNP cord-022526-j9kg00qf 2107 32 body body NN cord-022526-j9kg00qf 2107 33 mass mass NN cord-022526-j9kg00qf 2107 34 ) ) -RRB- cord-022526-j9kg00qf 2107 35 greatly greatly RB cord-022526-j9kg00qf 2107 36 exceeding exceed VBG cord-022526-j9kg00qf 2107 37 current current JJ cord-022526-j9kg00qf 2107 38 recommendations recommendation NNS cord-022526-j9kg00qf 2107 39 . . . cord-022526-j9kg00qf 2108 1 159 159 CD cord-022526-j9kg00qf 2109 1 Although although IN cord-022526-j9kg00qf 2109 2 single single JJ cord-022526-j9kg00qf 2109 3 doses dose NNS cord-022526-j9kg00qf 2109 4 of of IN cord-022526-j9kg00qf 2109 5 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 2109 6 are be VBP cord-022526-j9kg00qf 2109 7 unlikely unlikely JJ cord-022526-j9kg00qf 2109 8 to to TO cord-022526-j9kg00qf 2109 9 carry carry VB cord-022526-j9kg00qf 2109 10 a a DT cord-022526-j9kg00qf 2109 11 disproportionate disproportionate JJ cord-022526-j9kg00qf 2109 12 risk risk NN cord-022526-j9kg00qf 2109 13 of of IN cord-022526-j9kg00qf 2109 14 side side NN cord-022526-j9kg00qf 2109 15 effects effect NNS cord-022526-j9kg00qf 2109 16 , , , cord-022526-j9kg00qf 2109 17 one one PRP cord-022526-j9kg00qf 2109 18 should should MD cord-022526-j9kg00qf 2109 19 consider consider VB cord-022526-j9kg00qf 2109 20 the the DT cord-022526-j9kg00qf 2109 21 suggested suggest VBN cord-022526-j9kg00qf 2109 22 association association NN cord-022526-j9kg00qf 2109 23 of of IN cord-022526-j9kg00qf 2109 24 laminitis laminitis NN cord-022526-j9kg00qf 2109 25 with with IN cord-022526-j9kg00qf 2109 26 corticosteroid corticosteroid NN cord-022526-j9kg00qf 2109 27 use use NN cord-022526-j9kg00qf 2109 28 in in IN cord-022526-j9kg00qf 2109 29 horses horse NNS cord-022526-j9kg00qf 2109 30 . . . cord-022526-j9kg00qf 2110 1 In in IN cord-022526-j9kg00qf 2110 2 cases case NNS cord-022526-j9kg00qf 2110 3 of of IN cord-022526-j9kg00qf 2110 4 sepsis sepsis NN cord-022526-j9kg00qf 2110 5 , , , cord-022526-j9kg00qf 2110 6 further further JJ cord-022526-j9kg00qf 2110 7 immunosuppressive immunosuppressive JJ cord-022526-j9kg00qf 2110 8 effects effect NNS cord-022526-j9kg00qf 2110 9 could could MD cord-022526-j9kg00qf 2110 10 be be VB cord-022526-j9kg00qf 2110 11 detrimental detrimental JJ cord-022526-j9kg00qf 2110 12 . . . cord-022526-j9kg00qf 2111 1 In in IN cord-022526-j9kg00qf 2111 2 human human JJ cord-022526-j9kg00qf 2111 3 patients patient NNS cord-022526-j9kg00qf 2111 4 with with IN cord-022526-j9kg00qf 2111 5 certain certain JJ cord-022526-j9kg00qf 2111 6 types type NNS cord-022526-j9kg00qf 2111 7 of of IN cord-022526-j9kg00qf 2111 8 septic septic JJ cord-022526-j9kg00qf 2111 9 shock shock NN cord-022526-j9kg00qf 2111 10 , , , cord-022526-j9kg00qf 2111 11 dysfunction dysfunction NN cord-022526-j9kg00qf 2111 12 of of IN cord-022526-j9kg00qf 2111 13 the the DT cord-022526-j9kg00qf 2111 14 hypothalamic hypothalamic JJ cord-022526-j9kg00qf 2111 15 - - HYPH cord-022526-j9kg00qf 2111 16 pituitary pituitary NN cord-022526-j9kg00qf 2111 17 - - HYPH cord-022526-j9kg00qf 2111 18 adrenal adrenal NN cord-022526-j9kg00qf 2111 19 axis axis NN cord-022526-j9kg00qf 2111 20 has have VBZ cord-022526-j9kg00qf 2111 21 been be VBN cord-022526-j9kg00qf 2111 22 recognized recognize VBN cord-022526-j9kg00qf 2111 23 and and CC cord-022526-j9kg00qf 2111 24 successfully successfully RB cord-022526-j9kg00qf 2111 25 treated treat VBN cord-022526-j9kg00qf 2111 26 with with IN cord-022526-j9kg00qf 2111 27 hydrocortisone hydrocortisone NN cord-022526-j9kg00qf 2111 28 replacement replacement NN cord-022526-j9kg00qf 2111 29 therapy therapy NN cord-022526-j9kg00qf 2111 30 . . . cord-022526-j9kg00qf 2112 1 161 161 CD cord-022526-j9kg00qf 2112 2 Use Use NNP cord-022526-j9kg00qf 2112 3 of of IN cord-022526-j9kg00qf 2112 4 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 2112 5 for for IN cord-022526-j9kg00qf 2112 6 this this DT cord-022526-j9kg00qf 2112 7 indication indication NN cord-022526-j9kg00qf 2112 8 has have VBZ cord-022526-j9kg00qf 2112 9 not not RB cord-022526-j9kg00qf 2112 10 been be VBN cord-022526-j9kg00qf 2112 11 evaluated evaluate VBN cord-022526-j9kg00qf 2112 12 in in IN cord-022526-j9kg00qf 2112 13 horses horse NNS cord-022526-j9kg00qf 2112 14 . . . cord-022526-j9kg00qf 2113 1 Pentoxifylline Pentoxifylline NNP cord-022526-j9kg00qf 2113 2 , , , cord-022526-j9kg00qf 2113 3 a a DT cord-022526-j9kg00qf 2113 4 methylxanthine methylxanthine FW cord-022526-j9kg00qf 2113 5 derivative derivative JJ cord-022526-j9kg00qf 2113 6 and and CC cord-022526-j9kg00qf 2113 7 phosphodiesterase phosphodiesterase JJ cord-022526-j9kg00qf 2113 8 inhibitor inhibitor NN cord-022526-j9kg00qf 2113 9 , , , cord-022526-j9kg00qf 2113 10 has have VBZ cord-022526-j9kg00qf 2113 11 been be VBN cord-022526-j9kg00qf 2113 12 suggested suggest VBN cord-022526-j9kg00qf 2113 13 for for IN cord-022526-j9kg00qf 2113 14 use use NN cord-022526-j9kg00qf 2113 15 in in IN cord-022526-j9kg00qf 2113 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2113 17 because because IN cord-022526-j9kg00qf 2113 18 of of IN cord-022526-j9kg00qf 2113 19 its -PRON- PRP$ cord-022526-j9kg00qf 2113 20 effects effect NNS cord-022526-j9kg00qf 2113 21 on on IN cord-022526-j9kg00qf 2113 22 neutrophil neutrophil NN cord-022526-j9kg00qf 2113 23 function function NN cord-022526-j9kg00qf 2113 24 and and CC cord-022526-j9kg00qf 2113 25 its -PRON- PRP$ cord-022526-j9kg00qf 2113 26 ability ability NN cord-022526-j9kg00qf 2113 27 to to TO cord-022526-j9kg00qf 2113 28 inhibit inhibit VB cord-022526-j9kg00qf 2113 29 the the DT cord-022526-j9kg00qf 2113 30 production production NN cord-022526-j9kg00qf 2113 31 of of IN cord-022526-j9kg00qf 2113 32 various various JJ cord-022526-j9kg00qf 2113 33 cytokines cytokine NNS cord-022526-j9kg00qf 2113 34 , , , cord-022526-j9kg00qf 2113 35 interferons interferon NNS cord-022526-j9kg00qf 2113 36 , , , cord-022526-j9kg00qf 2113 37 and and CC cord-022526-j9kg00qf 2113 38 thromboplastin thromboplastin NNP cord-022526-j9kg00qf 2113 39 . . . cord-022526-j9kg00qf 2114 1 Decreased decrease VBN cord-022526-j9kg00qf 2114 2 production production NN cord-022526-j9kg00qf 2114 3 of of IN cord-022526-j9kg00qf 2114 4 TNF TNF NNP cord-022526-j9kg00qf 2114 5 , , , cord-022526-j9kg00qf 2114 6 IL-6 IL-6 NNP cord-022526-j9kg00qf 2114 7 , , , cord-022526-j9kg00qf 2114 8 TXB TXB NNP cord-022526-j9kg00qf 2114 9 2 2 CD cord-022526-j9kg00qf 2114 10 , , , cord-022526-j9kg00qf 2114 11 and and CC cord-022526-j9kg00qf 2114 12 thromboplastin thromboplastin VBZ cord-022526-j9kg00qf 2114 13 in in IN cord-022526-j9kg00qf 2114 14 response response NN cord-022526-j9kg00qf 2114 15 to to IN cord-022526-j9kg00qf 2114 16 endotoxin endotoxin NN cord-022526-j9kg00qf 2114 17 was be VBD cord-022526-j9kg00qf 2114 18 shown show VBN cord-022526-j9kg00qf 2114 19 in in IN cord-022526-j9kg00qf 2114 20 an an DT cord-022526-j9kg00qf 2114 21 equine equine JJ cord-022526-j9kg00qf 2114 22 ex ex FW cord-022526-j9kg00qf 2114 23 vivo vivo NN cord-022526-j9kg00qf 2114 24 model model NN cord-022526-j9kg00qf 2114 25 . . . cord-022526-j9kg00qf 2115 1 162 162 CD cord-022526-j9kg00qf 2116 1 In in IN cord-022526-j9kg00qf 2116 2 horses horse NNS cord-022526-j9kg00qf 2116 3 given give VBN cord-022526-j9kg00qf 2116 4 endotoxin endotoxin NN cord-022526-j9kg00qf 2116 5 followed follow VBN cord-022526-j9kg00qf 2116 6 by by IN cord-022526-j9kg00qf 2116 7 treatment treatment NN cord-022526-j9kg00qf 2116 8 with with IN cord-022526-j9kg00qf 2116 9 pentoxifylline pentoxifylline NNP cord-022526-j9kg00qf 2116 10 ( ( -LRB- cord-022526-j9kg00qf 2116 11 7.5 7.5 CD cord-022526-j9kg00qf 2116 12 mg mg NNP cord-022526-j9kg00qf 2116 13 / / SYM cord-022526-j9kg00qf 2116 14 kg kg NNP cord-022526-j9kg00qf 2116 15 body body NN cord-022526-j9kg00qf 2116 16 mass mass NN cord-022526-j9kg00qf 2116 17 followed follow VBN cord-022526-j9kg00qf 2116 18 by by IN cord-022526-j9kg00qf 2116 19 continuous continuous JJ cord-022526-j9kg00qf 2116 20 infusion infusion NN cord-022526-j9kg00qf 2116 21 of of IN cord-022526-j9kg00qf 2116 22 3 3 CD cord-022526-j9kg00qf 2116 23 mg mg NNP cord-022526-j9kg00qf 2116 24 / / SYM cord-022526-j9kg00qf 2116 25 kg kg NNP cord-022526-j9kg00qf 2116 26 / / SYM cord-022526-j9kg00qf 2116 27 hr hr NN cord-022526-j9kg00qf 2116 28 for for IN cord-022526-j9kg00qf 2116 29 3 3 CD cord-022526-j9kg00qf 2116 30 hours hour NNS cord-022526-j9kg00qf 2116 31 ) ) -RRB- cord-022526-j9kg00qf 2116 32 , , , cord-022526-j9kg00qf 2116 33 however however RB cord-022526-j9kg00qf 2116 34 , , , cord-022526-j9kg00qf 2116 35 only only RB cord-022526-j9kg00qf 2116 36 minimal minimal JJ cord-022526-j9kg00qf 2116 37 beneficial beneficial JJ cord-022526-j9kg00qf 2116 38 effects effect NNS cord-022526-j9kg00qf 2116 39 were be VBD cord-022526-j9kg00qf 2116 40 observed observe VBN cord-022526-j9kg00qf 2116 41 . . . cord-022526-j9kg00qf 2117 1 163 163 CD cord-022526-j9kg00qf 2117 2 Treatment treatment NN cord-022526-j9kg00qf 2117 3 significantly significantly RB cord-022526-j9kg00qf 2117 4 improved improve VBD cord-022526-j9kg00qf 2117 5 body body NN cord-022526-j9kg00qf 2117 6 temperature temperature NN cord-022526-j9kg00qf 2117 7 , , , cord-022526-j9kg00qf 2117 8 respiratory respiratory JJ cord-022526-j9kg00qf 2117 9 rate rate NN cord-022526-j9kg00qf 2117 10 , , , cord-022526-j9kg00qf 2117 11 and and CC cord-022526-j9kg00qf 2117 12 whole whole JJ cord-022526-j9kg00qf 2117 13 blood blood NN cord-022526-j9kg00qf 2117 14 recalcification recalcification NN cord-022526-j9kg00qf 2117 15 time time NN cord-022526-j9kg00qf 2117 16 , , , cord-022526-j9kg00qf 2117 17 but but CC cord-022526-j9kg00qf 2117 18 no no DT cord-022526-j9kg00qf 2117 19 effect effect NN cord-022526-j9kg00qf 2117 20 was be VBD cord-022526-j9kg00qf 2117 21 observed observe VBN cord-022526-j9kg00qf 2117 22 regarding regard VBG cord-022526-j9kg00qf 2117 23 heart heart NN cord-022526-j9kg00qf 2117 24 rate rate NN cord-022526-j9kg00qf 2117 25 , , , cord-022526-j9kg00qf 2117 26 blood blood NN cord-022526-j9kg00qf 2117 27 pressure pressure NN cord-022526-j9kg00qf 2117 28 , , , cord-022526-j9kg00qf 2117 29 leukocyte leukocyte NN cord-022526-j9kg00qf 2117 30 count count NN cord-022526-j9kg00qf 2117 31 , , , cord-022526-j9kg00qf 2117 32 plasma plasma NN cord-022526-j9kg00qf 2117 33 fibrinogen fibrinogen NN cord-022526-j9kg00qf 2117 34 concentration concentration NN cord-022526-j9kg00qf 2117 35 , , , cord-022526-j9kg00qf 2117 36 and and CC cord-022526-j9kg00qf 2117 37 serum serum NN cord-022526-j9kg00qf 2117 38 cytokine cytokine NN cord-022526-j9kg00qf 2117 39 concentrations concentration NNS cord-022526-j9kg00qf 2117 40 . . . cord-022526-j9kg00qf 2118 1 The the DT cord-022526-j9kg00qf 2118 2 conclusion conclusion NN cord-022526-j9kg00qf 2118 3 was be VBD cord-022526-j9kg00qf 2118 4 that that IN cord-022526-j9kg00qf 2118 5 benefits benefit NNS cord-022526-j9kg00qf 2118 6 of of IN cord-022526-j9kg00qf 2118 7 treatment treatment NN cord-022526-j9kg00qf 2118 8 with with IN cord-022526-j9kg00qf 2118 9 pentoxifylline pentoxifylline NNP cord-022526-j9kg00qf 2118 10 might may MD cord-022526-j9kg00qf 2118 11 be be VB cord-022526-j9kg00qf 2118 12 restricted restrict VBN cord-022526-j9kg00qf 2118 13 to to IN cord-022526-j9kg00qf 2118 14 administration administration NN cord-022526-j9kg00qf 2118 15 of of IN cord-022526-j9kg00qf 2118 16 high high JJ cord-022526-j9kg00qf 2118 17 bolus bolus NN cord-022526-j9kg00qf 2118 18 doses dose NNS cord-022526-j9kg00qf 2118 19 or or CC cord-022526-j9kg00qf 2118 20 continuous continuous JJ cord-022526-j9kg00qf 2118 21 infusion infusion NN cord-022526-j9kg00qf 2118 22 early early RB cord-022526-j9kg00qf 2118 23 in in IN cord-022526-j9kg00qf 2118 24 the the DT cord-022526-j9kg00qf 2118 25 pathophysiologic pathophysiologic NN cord-022526-j9kg00qf 2118 26 process process NN cord-022526-j9kg00qf 2118 27 . . . cord-022526-j9kg00qf 2119 1 In in IN cord-022526-j9kg00qf 2119 2 an an DT cord-022526-j9kg00qf 2119 3 in in IN cord-022526-j9kg00qf 2119 4 vivo vivo FW cord-022526-j9kg00qf 2119 5 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2119 6 model model NN cord-022526-j9kg00qf 2119 7 in in IN cord-022526-j9kg00qf 2119 8 horses horse NNS cord-022526-j9kg00qf 2119 9 , , , cord-022526-j9kg00qf 2119 10 combination combination NN cord-022526-j9kg00qf 2119 11 of of IN cord-022526-j9kg00qf 2119 12 pentoxifylline pentoxifylline NNP cord-022526-j9kg00qf 2119 13 ( ( -LRB- cord-022526-j9kg00qf 2119 14 8 8 CD cord-022526-j9kg00qf 2119 15 mg mg NNP cord-022526-j9kg00qf 2119 16 / / SYM cord-022526-j9kg00qf 2119 17 kg kg NNP cord-022526-j9kg00qf 2119 18 body body NN cord-022526-j9kg00qf 2119 19 mass mass NN cord-022526-j9kg00qf 2119 20 ) ) -RRB- cord-022526-j9kg00qf 2119 21 and and CC cord-022526-j9kg00qf 2119 22 flunixin flunixin NNP cord-022526-j9kg00qf 2119 23 meglumine meglumine NNP cord-022526-j9kg00qf 2119 24 ( ( -LRB- cord-022526-j9kg00qf 2119 25 1.1 1.1 CD cord-022526-j9kg00qf 2119 26 mg mg NNP cord-022526-j9kg00qf 2119 27 / / SYM cord-022526-j9kg00qf 2119 28 kg kg NNP cord-022526-j9kg00qf 2119 29 body body NN cord-022526-j9kg00qf 2119 30 mass mass NN cord-022526-j9kg00qf 2119 31 ) ) -RRB- cord-022526-j9kg00qf 2119 32 was be VBD cord-022526-j9kg00qf 2119 33 found find VBN cord-022526-j9kg00qf 2119 34 to to TO cord-022526-j9kg00qf 2119 35 have have VB cord-022526-j9kg00qf 2119 36 greater great JJR cord-022526-j9kg00qf 2119 37 benefit benefit NN cord-022526-j9kg00qf 2119 38 than than IN cord-022526-j9kg00qf 2119 39 each each DT cord-022526-j9kg00qf 2119 40 treatment treatment NN cord-022526-j9kg00qf 2119 41 on on IN cord-022526-j9kg00qf 2119 42 its -PRON- PRP$ cord-022526-j9kg00qf 2119 43 own own JJ cord-022526-j9kg00qf 2119 44 . . . cord-022526-j9kg00qf 2120 1 164 164 CD cord-022526-j9kg00qf 2121 1 The the DT cord-022526-j9kg00qf 2121 2 currently currently RB cord-022526-j9kg00qf 2121 3 recommended recommend VBN cord-022526-j9kg00qf 2121 4 dosage dosage NN cord-022526-j9kg00qf 2121 5 for for IN cord-022526-j9kg00qf 2121 6 oral oral JJ cord-022526-j9kg00qf 2121 7 administration administration NNP cord-022526-j9kg00qf 2121 8 of of IN cord-022526-j9kg00qf 2121 9 pentoxifylline pentoxifylline NNP cord-022526-j9kg00qf 2121 10 is be VBZ cord-022526-j9kg00qf 2121 11 8 8 CD cord-022526-j9kg00qf 2121 12 mg mg NNP cord-022526-j9kg00qf 2121 13 / / SYM cord-022526-j9kg00qf 2121 14 kg kg NN cord-022526-j9kg00qf 2121 15 every every DT cord-022526-j9kg00qf 2121 16 8 8 CD cord-022526-j9kg00qf 2121 17 hours hour NNS cord-022526-j9kg00qf 2121 18 . . . cord-022526-j9kg00qf 2122 1 Because because IN cord-022526-j9kg00qf 2122 2 of of IN cord-022526-j9kg00qf 2122 3 its -PRON- PRP$ cord-022526-j9kg00qf 2122 4 rheologic rheologic JJ cord-022526-j9kg00qf 2122 5 properties property NNS cord-022526-j9kg00qf 2122 6 , , , cord-022526-j9kg00qf 2122 7 that that RB cord-022526-j9kg00qf 2122 8 is is RB cord-022526-j9kg00qf 2122 9 , , , cord-022526-j9kg00qf 2122 10 the the DT cord-022526-j9kg00qf 2122 11 ability ability NN cord-022526-j9kg00qf 2122 12 to to TO cord-022526-j9kg00qf 2122 13 increase increase VB cord-022526-j9kg00qf 2122 14 erythrocyte erythrocyte NN cord-022526-j9kg00qf 2122 15 deformability deformability NN cord-022526-j9kg00qf 2122 16 and and CC cord-022526-j9kg00qf 2122 17 microvascular microvascular JJ cord-022526-j9kg00qf 2122 18 blood blood NN cord-022526-j9kg00qf 2122 19 flow flow NN cord-022526-j9kg00qf 2122 20 , , , cord-022526-j9kg00qf 2122 21 pentoxifylline pentoxifylline NNP cord-022526-j9kg00qf 2122 22 may may MD cord-022526-j9kg00qf 2122 23 be be VB cord-022526-j9kg00qf 2122 24 particularly particularly RB cord-022526-j9kg00qf 2122 25 useful useful JJ cord-022526-j9kg00qf 2122 26 in in IN cord-022526-j9kg00qf 2122 27 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 2122 28 patients patient NNS cord-022526-j9kg00qf 2122 29 showing show VBG cord-022526-j9kg00qf 2122 30 evidence evidence NN cord-022526-j9kg00qf 2122 31 of of IN cord-022526-j9kg00qf 2122 32 laminitis laminitis NN cord-022526-j9kg00qf 2122 33 . . . cord-022526-j9kg00qf 2123 1 An an DT cord-022526-j9kg00qf 2123 2 intravenous intravenous JJ cord-022526-j9kg00qf 2123 3 preparation preparation NN cord-022526-j9kg00qf 2123 4 of of IN cord-022526-j9kg00qf 2123 5 pentoxifylline pentoxifylline NN cord-022526-j9kg00qf 2123 6 is be VBZ cord-022526-j9kg00qf 2123 7 not not RB cord-022526-j9kg00qf 2123 8 commercially commercially RB cord-022526-j9kg00qf 2123 9 available available JJ cord-022526-j9kg00qf 2123 10 . . . cord-022526-j9kg00qf 2124 1 Dimethyl dimethyl NN cord-022526-j9kg00qf 2124 2 sulfoxide sulfoxide NN cord-022526-j9kg00qf 2124 3 ( ( -LRB- cord-022526-j9kg00qf 2124 4 DMSO DMSO NNP cord-022526-j9kg00qf 2124 5 ) ) -RRB- cord-022526-j9kg00qf 2124 6 is be VBZ cord-022526-j9kg00qf 2124 7 used use VBN cord-022526-j9kg00qf 2124 8 frequently frequently RB cord-022526-j9kg00qf 2124 9 in in IN cord-022526-j9kg00qf 2124 10 an an DT cord-022526-j9kg00qf 2124 11 attempt attempt NN cord-022526-j9kg00qf 2124 12 to to TO cord-022526-j9kg00qf 2124 13 scavenge scavenge VB cord-022526-j9kg00qf 2124 14 oxygen oxygen NN cord-022526-j9kg00qf 2124 15 - - HYPH cord-022526-j9kg00qf 2124 16 derived derive VBN cord-022526-j9kg00qf 2124 17 radicals radical NNS cord-022526-j9kg00qf 2124 18 . . . cord-022526-j9kg00qf 2125 1 The the DT cord-022526-j9kg00qf 2125 2 treatment treatment NN cord-022526-j9kg00qf 2125 3 may may MD cord-022526-j9kg00qf 2125 4 be be VB cord-022526-j9kg00qf 2125 5 most most RBS cord-022526-j9kg00qf 2125 6 appropriate appropriate JJ cord-022526-j9kg00qf 2125 7 in in IN cord-022526-j9kg00qf 2125 8 cases case NNS cord-022526-j9kg00qf 2125 9 of of IN cord-022526-j9kg00qf 2125 10 ischemia ischemia NN cord-022526-j9kg00qf 2125 11 - - HYPH cord-022526-j9kg00qf 2125 12 induced induce VBN cord-022526-j9kg00qf 2125 13 intestinal intestinal JJ cord-022526-j9kg00qf 2125 14 damage damage NN cord-022526-j9kg00qf 2125 15 and and CC cord-022526-j9kg00qf 2125 16 associated associated JJ cord-022526-j9kg00qf 2125 17 reperfusion reperfusion NN cord-022526-j9kg00qf 2125 18 injury injury NN cord-022526-j9kg00qf 2125 19 . . . cord-022526-j9kg00qf 2126 1 However however RB cord-022526-j9kg00qf 2126 2 , , , cord-022526-j9kg00qf 2126 3 DMSO DMSO NNP cord-022526-j9kg00qf 2126 4 failed fail VBD cord-022526-j9kg00qf 2126 5 to to TO cord-022526-j9kg00qf 2126 6 show show VB cord-022526-j9kg00qf 2126 7 beneficial beneficial JJ cord-022526-j9kg00qf 2126 8 effects effect NNS cord-022526-j9kg00qf 2126 9 in in IN cord-022526-j9kg00qf 2126 10 an an DT cord-022526-j9kg00qf 2126 11 experimental experimental JJ cord-022526-j9kg00qf 2126 12 model model NN cord-022526-j9kg00qf 2126 13 of of IN cord-022526-j9kg00qf 2126 14 intestinal intestinal JJ cord-022526-j9kg00qf 2126 15 ischemia ischemia NN cord-022526-j9kg00qf 2126 16 when when WRB cord-022526-j9kg00qf 2126 17 administered administer VBN cord-022526-j9kg00qf 2126 18 on on IN cord-022526-j9kg00qf 2126 19 reperfusion reperfusion NN cord-022526-j9kg00qf 2126 20 of of IN cord-022526-j9kg00qf 2126 21 the the DT cord-022526-j9kg00qf 2126 22 ischemic ischemic JJ cord-022526-j9kg00qf 2126 23 intestine intestine NN cord-022526-j9kg00qf 2126 24 . . . cord-022526-j9kg00qf 2127 1 165 165 CD cord-022526-j9kg00qf 2127 2 DMSO DMSO NNP cord-022526-j9kg00qf 2127 3 at at IN cord-022526-j9kg00qf 2127 4 the the DT cord-022526-j9kg00qf 2127 5 commonly commonly RB cord-022526-j9kg00qf 2127 6 used use VBN cord-022526-j9kg00qf 2127 7 dose dose NN cord-022526-j9kg00qf 2127 8 of of IN cord-022526-j9kg00qf 2127 9 1 1 CD cord-022526-j9kg00qf 2127 10 g g NN cord-022526-j9kg00qf 2127 11 / / SYM cord-022526-j9kg00qf 2127 12 kg kg NNP cord-022526-j9kg00qf 2127 13 body body NN cord-022526-j9kg00qf 2127 14 mass mass NN cord-022526-j9kg00qf 2127 15 was be VBD cord-022526-j9kg00qf 2127 16 shown show VBN cord-022526-j9kg00qf 2127 17 to to TO cord-022526-j9kg00qf 2127 18 increase increase VB cord-022526-j9kg00qf 2127 19 mucosal mucosal JJ cord-022526-j9kg00qf 2127 20 loss loss NN cord-022526-j9kg00qf 2127 21 after after IN cord-022526-j9kg00qf 2127 22 ischemia ischemia NN cord-022526-j9kg00qf 2127 23 and and CC cord-022526-j9kg00qf 2127 24 reperfusion reperfusion NN cord-022526-j9kg00qf 2127 25 of of IN cord-022526-j9kg00qf 2127 26 the the DT cord-022526-j9kg00qf 2127 27 large large JJ cord-022526-j9kg00qf 2127 28 colon colon NN cord-022526-j9kg00qf 2127 29 , , , cord-022526-j9kg00qf 2127 30 166 166 CD cord-022526-j9kg00qf 2127 31 and and CC cord-022526-j9kg00qf 2127 32 hence hence RB cord-022526-j9kg00qf 2127 33 a a DT cord-022526-j9kg00qf 2127 34 reduced reduced JJ cord-022526-j9kg00qf 2127 35 dose dose NN cord-022526-j9kg00qf 2127 36 of of IN cord-022526-j9kg00qf 2127 37 0.1 0.1 CD cord-022526-j9kg00qf 2127 38 g g NN cord-022526-j9kg00qf 2127 39 / / SYM cord-022526-j9kg00qf 2127 40 kg kg NN cord-022526-j9kg00qf 2127 41 body body NN cord-022526-j9kg00qf 2127 42 mass mass NN cord-022526-j9kg00qf 2127 43 has have VBZ cord-022526-j9kg00qf 2127 44 been be VBN cord-022526-j9kg00qf 2127 45 proposed propose VBN cord-022526-j9kg00qf 2127 46 for for IN cord-022526-j9kg00qf 2127 47 cases case NNS cord-022526-j9kg00qf 2127 48 of of IN cord-022526-j9kg00qf 2127 49 intestinal intestinal JJ cord-022526-j9kg00qf 2127 50 ischemia ischemia NN cord-022526-j9kg00qf 2127 51 . . . cord-022526-j9kg00qf 2128 1 For for IN cord-022526-j9kg00qf 2128 2 intravenous intravenous JJ cord-022526-j9kg00qf 2128 3 administration administration NN cord-022526-j9kg00qf 2128 4 , , , cord-022526-j9kg00qf 2128 5 DMSO DMSO NNP cord-022526-j9kg00qf 2128 6 needs need VBZ cord-022526-j9kg00qf 2128 7 to to TO cord-022526-j9kg00qf 2128 8 be be VB cord-022526-j9kg00qf 2128 9 diluted dilute VBN cord-022526-j9kg00qf 2128 10 in in IN cord-022526-j9kg00qf 2128 11 polyionic polyionic JJ cord-022526-j9kg00qf 2128 12 solutions solution NNS cord-022526-j9kg00qf 2128 13 to to IN cord-022526-j9kg00qf 2128 14 a a DT cord-022526-j9kg00qf 2128 15 concentration concentration NN cord-022526-j9kg00qf 2128 16 not not RB cord-022526-j9kg00qf 2128 17 exceeding exceed VBG cord-022526-j9kg00qf 2128 18 10 10 CD cord-022526-j9kg00qf 2128 19 % % NN cord-022526-j9kg00qf 2128 20 . . . cord-022526-j9kg00qf 2129 1 Oral oral JJ cord-022526-j9kg00qf 2129 2 administration administration NN cord-022526-j9kg00qf 2129 3 of of IN cord-022526-j9kg00qf 2129 4 a a DT cord-022526-j9kg00qf 2129 5 10 10 CD cord-022526-j9kg00qf 2129 6 % % NN cord-022526-j9kg00qf 2129 7 to to TO cord-022526-j9kg00qf 2129 8 20 20 CD cord-022526-j9kg00qf 2129 9 % % NN cord-022526-j9kg00qf 2129 10 solution solution NN cord-022526-j9kg00qf 2129 11 via via IN cord-022526-j9kg00qf 2129 12 nasogastric nasogastric NN cord-022526-j9kg00qf 2129 13 intubation intubation NN cord-022526-j9kg00qf 2129 14 is be VBZ cord-022526-j9kg00qf 2129 15 also also RB cord-022526-j9kg00qf 2129 16 possible possible JJ cord-022526-j9kg00qf 2129 17 . . . cord-022526-j9kg00qf 2130 1 Aside aside RB cord-022526-j9kg00qf 2130 2 from from IN cord-022526-j9kg00qf 2130 3 DMSO DMSO NNP cord-022526-j9kg00qf 2130 4 the the DT cord-022526-j9kg00qf 2130 5 xanthine xanthine NN cord-022526-j9kg00qf 2130 6 oxidase oxidase NN cord-022526-j9kg00qf 2130 7 inhibitor inhibitor NN cord-022526-j9kg00qf 2130 8 allopurinol allopurinol NNP cord-022526-j9kg00qf 2130 9 has have VBZ cord-022526-j9kg00qf 2130 10 been be VBN cord-022526-j9kg00qf 2130 11 suggested suggest VBN cord-022526-j9kg00qf 2130 12 as as IN cord-022526-j9kg00qf 2130 13 a a DT cord-022526-j9kg00qf 2130 14 treatment treatment NN cord-022526-j9kg00qf 2130 15 to to TO cord-022526-j9kg00qf 2130 16 prevent prevent VB cord-022526-j9kg00qf 2130 17 oxygen oxygen NN cord-022526-j9kg00qf 2130 18 radical radical JJ cord-022526-j9kg00qf 2130 19 - - HYPH cord-022526-j9kg00qf 2130 20 induced induce VBN cord-022526-j9kg00qf 2130 21 tissue tissue NN cord-022526-j9kg00qf 2130 22 damage damage NN cord-022526-j9kg00qf 2130 23 . . . cord-022526-j9kg00qf 2131 1 During during IN cord-022526-j9kg00qf 2131 2 periods period NNS cord-022526-j9kg00qf 2131 3 of of IN cord-022526-j9kg00qf 2131 4 ischemia ischemia NN cord-022526-j9kg00qf 2131 5 , , , cord-022526-j9kg00qf 2131 6 tissue tissue NN cord-022526-j9kg00qf 2131 7 xanthine xanthine NN cord-022526-j9kg00qf 2131 8 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 2131 9 is be VBZ cord-022526-j9kg00qf 2131 10 converted convert VBN cord-022526-j9kg00qf 2131 11 to to IN cord-022526-j9kg00qf 2131 12 xanthine xanthine NN cord-022526-j9kg00qf 2131 13 oxidase oxidase NN cord-022526-j9kg00qf 2131 14 , , , cord-022526-j9kg00qf 2131 15 which which WDT cord-022526-j9kg00qf 2131 16 on on IN cord-022526-j9kg00qf 2131 17 reperfusion reperfusion NN cord-022526-j9kg00qf 2131 18 catalyzes catalyze VBZ cord-022526-j9kg00qf 2131 19 the the DT cord-022526-j9kg00qf 2131 20 generation generation NN cord-022526-j9kg00qf 2131 21 of of IN cord-022526-j9kg00qf 2131 22 superoxide superoxide NN cord-022526-j9kg00qf 2131 23 radicals radical NNS cord-022526-j9kg00qf 2131 24 . . . cord-022526-j9kg00qf 2132 1 167 167 CD cord-022526-j9kg00qf 2132 2 , , , cord-022526-j9kg00qf 2132 3 168 168 CD cord-022526-j9kg00qf 2132 4 Evaluation evaluation NN cord-022526-j9kg00qf 2132 5 in in IN cord-022526-j9kg00qf 2132 6 horses horse NNS cord-022526-j9kg00qf 2132 7 showed show VBD cord-022526-j9kg00qf 2132 8 beneficial beneficial JJ cord-022526-j9kg00qf 2132 9 effects effect NNS cord-022526-j9kg00qf 2132 10 of of IN cord-022526-j9kg00qf 2132 11 5 5 CD cord-022526-j9kg00qf 2132 12 mg mg NNP cord-022526-j9kg00qf 2132 13 allopurinol allopurinol NN cord-022526-j9kg00qf 2132 14 per per IN cord-022526-j9kg00qf 2132 15 kilogram kilogram NN cord-022526-j9kg00qf 2132 16 body body NN cord-022526-j9kg00qf 2132 17 mass mass NN cord-022526-j9kg00qf 2132 18 administered administer VBD cord-022526-j9kg00qf 2132 19 12 12 CD cord-022526-j9kg00qf 2132 20 hours hour NNS cord-022526-j9kg00qf 2132 21 before before IN cord-022526-j9kg00qf 2132 22 endotoxin endotoxin NN cord-022526-j9kg00qf 2132 23 challenge challenge NN cord-022526-j9kg00qf 2132 24 . . . cord-022526-j9kg00qf 2133 1 169 169 CD cord-022526-j9kg00qf 2134 1 In in IN cord-022526-j9kg00qf 2134 2 another another DT cord-022526-j9kg00qf 2134 3 study study NN cord-022526-j9kg00qf 2134 4 , , , cord-022526-j9kg00qf 2134 5 mucosal mucosal JJ cord-022526-j9kg00qf 2134 6 damage damage NN cord-022526-j9kg00qf 2134 7 attributable attributable JJ cord-022526-j9kg00qf 2134 8 to to IN cord-022526-j9kg00qf 2134 9 oxygen oxygen NN cord-022526-j9kg00qf 2134 10 - - HYPH cord-022526-j9kg00qf 2134 11 derived derive VBN cord-022526-j9kg00qf 2134 12 free free JJ cord-022526-j9kg00qf 2134 13 radicals radical NNS cord-022526-j9kg00qf 2134 14 was be VBD cord-022526-j9kg00qf 2134 15 not not RB cord-022526-j9kg00qf 2134 16 attenuated attenuate VBN cord-022526-j9kg00qf 2134 17 by by IN cord-022526-j9kg00qf 2134 18 allopurinol allopurinol NN cord-022526-j9kg00qf 2134 19 in in IN cord-022526-j9kg00qf 2134 20 an an DT cord-022526-j9kg00qf 2134 21 experimental experimental JJ cord-022526-j9kg00qf 2134 22 ischemia ischemia NN cord-022526-j9kg00qf 2134 23 - - HYPH cord-022526-j9kg00qf 2134 24 reperfusion reperfusion NN cord-022526-j9kg00qf 2134 25 model model NN cord-022526-j9kg00qf 2134 26 . . . cord-022526-j9kg00qf 2135 1 166 166 CD cord-022526-j9kg00qf 2135 2 Lidocaine lidocaine NN cord-022526-j9kg00qf 2135 3 given give VBN cord-022526-j9kg00qf 2135 4 intravenously intravenously RB cord-022526-j9kg00qf 2135 5 has have VBZ cord-022526-j9kg00qf 2135 6 been be VBN cord-022526-j9kg00qf 2135 7 suggested suggest VBN cord-022526-j9kg00qf 2135 8 as as IN cord-022526-j9kg00qf 2135 9 an an DT cord-022526-j9kg00qf 2135 10 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2135 11 , , , cord-022526-j9kg00qf 2135 12 analgesic analgesic JJ cord-022526-j9kg00qf 2135 13 , , , cord-022526-j9kg00qf 2135 14 and and CC cord-022526-j9kg00qf 2135 15 prokinetic prokinetic JJ cord-022526-j9kg00qf 2135 16 agent agent NN cord-022526-j9kg00qf 2135 17 , , , cord-022526-j9kg00qf 2135 18 and and CC cord-022526-j9kg00qf 2135 19 some some DT cord-022526-j9kg00qf 2135 20 clinicians clinician NNS cord-022526-j9kg00qf 2135 21 use use VBP cord-022526-j9kg00qf 2135 22 it -PRON- PRP cord-022526-j9kg00qf 2135 23 to to TO cord-022526-j9kg00qf 2135 24 treat treat VB cord-022526-j9kg00qf 2135 25 colic colic NN cord-022526-j9kg00qf 2135 26 and and CC cord-022526-j9kg00qf 2135 27 laminitis laminitis NN cord-022526-j9kg00qf 2135 28 in in IN cord-022526-j9kg00qf 2135 29 horses horse NNS cord-022526-j9kg00qf 2135 30 . . . cord-022526-j9kg00qf 2136 1 In in IN cord-022526-j9kg00qf 2136 2 an an DT cord-022526-j9kg00qf 2136 3 experimental experimental JJ cord-022526-j9kg00qf 2136 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2136 5 model model NN cord-022526-j9kg00qf 2136 6 in in IN cord-022526-j9kg00qf 2136 7 rabbits rabbit NNS cord-022526-j9kg00qf 2136 8 , , , cord-022526-j9kg00qf 2136 9 lidocaine lidocaine NN cord-022526-j9kg00qf 2136 10 was be VBD cord-022526-j9kg00qf 2136 11 found find VBN cord-022526-j9kg00qf 2136 12 to to TO cord-022526-j9kg00qf 2136 13 inhibit inhibit VB cord-022526-j9kg00qf 2136 14 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 2136 15 and and CC cord-022526-j9kg00qf 2136 16 cytokine cytokine JJ cord-022526-j9kg00qf 2136 17 responses response NNS cord-022526-j9kg00qf 2136 18 to to TO cord-022526-j9kg00qf 2136 19 endotoxin endotoxin VB cord-022526-j9kg00qf 2136 20 profoundly profoundly RB cord-022526-j9kg00qf 2136 21 if if IN cord-022526-j9kg00qf 2136 22 given give VBN cord-022526-j9kg00qf 2136 23 immediately immediately RB cord-022526-j9kg00qf 2136 24 following follow VBG cord-022526-j9kg00qf 2136 25 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2136 26 infusion infusion NN cord-022526-j9kg00qf 2136 27 . . . cord-022526-j9kg00qf 2137 1 170 170 CD cord-022526-j9kg00qf 2137 2 Use use NN cord-022526-j9kg00qf 2137 3 of of IN cord-022526-j9kg00qf 2137 4 lidocaine lidocaine NN cord-022526-j9kg00qf 2137 5 therefore therefore RB cord-022526-j9kg00qf 2137 6 may may MD cord-022526-j9kg00qf 2137 7 have have VB cord-022526-j9kg00qf 2137 8 additional additional JJ cord-022526-j9kg00qf 2137 9 merit merit NN cord-022526-j9kg00qf 2137 10 in in IN cord-022526-j9kg00qf 2137 11 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 2137 12 patients patient NNS cord-022526-j9kg00qf 2137 13 . . . cord-022526-j9kg00qf 2138 1 A a DT cord-022526-j9kg00qf 2138 2 common common JJ cord-022526-j9kg00qf 2138 3 regimen regimen NN cord-022526-j9kg00qf 2138 4 for for IN cord-022526-j9kg00qf 2138 5 lidocaine lidocaine NN cord-022526-j9kg00qf 2138 6 use use NN cord-022526-j9kg00qf 2138 7 in in IN cord-022526-j9kg00qf 2138 8 horses horse NNS cord-022526-j9kg00qf 2138 9 is be VBZ cord-022526-j9kg00qf 2138 10 administration administration NN cord-022526-j9kg00qf 2138 11 of of IN cord-022526-j9kg00qf 2138 12 an an DT cord-022526-j9kg00qf 2138 13 initial initial JJ cord-022526-j9kg00qf 2138 14 bolus bolus NN cord-022526-j9kg00qf 2139 1 ( ( -LRB- cord-022526-j9kg00qf 2139 2 1.3 1.3 CD cord-022526-j9kg00qf 2139 3 mg mg NNP cord-022526-j9kg00qf 2139 4 / / SYM cord-022526-j9kg00qf 2139 5 kg kg NNP cord-022526-j9kg00qf 2139 6 body body NN cord-022526-j9kg00qf 2139 7 mass mass NN cord-022526-j9kg00qf 2139 8 ) ) -RRB- cord-022526-j9kg00qf 2139 9 SECTION section NN cord-022526-j9kg00qf 2139 10 13.7 13.7 CD cord-022526-j9kg00qf 2139 11 Endotoxemia Endotoxemia NNP cord-022526-j9kg00qf 2139 12 followed follow VBD cord-022526-j9kg00qf 2139 13 by by IN cord-022526-j9kg00qf 2139 14 continuous continuous JJ cord-022526-j9kg00qf 2139 15 infusion infusion NN cord-022526-j9kg00qf 2139 16 at at IN cord-022526-j9kg00qf 2139 17 a a DT cord-022526-j9kg00qf 2139 18 rate rate NN cord-022526-j9kg00qf 2139 19 of of IN cord-022526-j9kg00qf 2139 20 0.05 0.05 CD cord-022526-j9kg00qf 2139 21 mg/ mg/ NN cord-022526-j9kg00qf 2139 22 kg kg NNP cord-022526-j9kg00qf 2139 23 / / SYM cord-022526-j9kg00qf 2139 24 min min NNP cord-022526-j9kg00qf 2139 25 . . . cord-022526-j9kg00qf 2140 1 One one PRP cord-022526-j9kg00qf 2140 2 should should MD cord-022526-j9kg00qf 2140 3 monitor monitor VB cord-022526-j9kg00qf 2140 4 patients patient NNS cord-022526-j9kg00qf 2140 5 for for IN cord-022526-j9kg00qf 2140 6 toxic toxic JJ cord-022526-j9kg00qf 2140 7 neurologic neurologic JJ cord-022526-j9kg00qf 2140 8 effects effect NNS cord-022526-j9kg00qf 2140 9 associated associate VBN cord-022526-j9kg00qf 2140 10 with with IN cord-022526-j9kg00qf 2140 11 a a DT cord-022526-j9kg00qf 2140 12 lidocaine lidocaine NN cord-022526-j9kg00qf 2140 13 overdose overdose NN cord-022526-j9kg00qf 2140 14 . . . cord-022526-j9kg00qf 2141 1 High high JJ cord-022526-j9kg00qf 2141 2 concentrations concentration NNS cord-022526-j9kg00qf 2141 3 of of IN cord-022526-j9kg00qf 2141 4 ω-3 ω-3 CD cord-022526-j9kg00qf 2141 5 fatty fatty JJ cord-022526-j9kg00qf 2141 6 acids acid NNS cord-022526-j9kg00qf 2141 7 can can MD cord-022526-j9kg00qf 2141 8 alter alter VB cord-022526-j9kg00qf 2141 9 the the DT cord-022526-j9kg00qf 2141 10 phospholipid phospholipid NN cord-022526-j9kg00qf 2141 11 composition composition NN cord-022526-j9kg00qf 2141 12 of of IN cord-022526-j9kg00qf 2141 13 cellular cellular JJ cord-022526-j9kg00qf 2141 14 membranes membrane NNS cord-022526-j9kg00qf 2141 15 toward toward IN cord-022526-j9kg00qf 2141 16 a a DT cord-022526-j9kg00qf 2141 17 decreased decreased JJ cord-022526-j9kg00qf 2141 18 ratio ratio NN cord-022526-j9kg00qf 2141 19 of of IN cord-022526-j9kg00qf 2141 20 ω-6 ω-6 NN cord-022526-j9kg00qf 2141 21 to to IN cord-022526-j9kg00qf 2141 22 ω-3 ω-3 CD cord-022526-j9kg00qf 2141 23 and and CC cord-022526-j9kg00qf 2141 24 thereby thereby RB cord-022526-j9kg00qf 2141 25 can can MD cord-022526-j9kg00qf 2141 26 affect affect VB cord-022526-j9kg00qf 2141 27 membrane membrane NN cord-022526-j9kg00qf 2141 28 functions function NNS cord-022526-j9kg00qf 2141 29 such such JJ cord-022526-j9kg00qf 2141 30 as as IN cord-022526-j9kg00qf 2141 31 phagocytosis phagocytosis NN cord-022526-j9kg00qf 2141 32 , , , cord-022526-j9kg00qf 2141 33 receptor receptor NN cord-022526-j9kg00qf 2141 34 binding binding NN cord-022526-j9kg00qf 2141 35 , , , cord-022526-j9kg00qf 2141 36 and and CC cord-022526-j9kg00qf 2141 37 activities activity NNS cord-022526-j9kg00qf 2141 38 of of IN cord-022526-j9kg00qf 2141 39 membrane membrane NN cord-022526-j9kg00qf 2141 40 - - HYPH cord-022526-j9kg00qf 2141 41 bound bind VBN cord-022526-j9kg00qf 2141 42 enzymes enzyme NNS cord-022526-j9kg00qf 2141 43 . . . cord-022526-j9kg00qf 2142 1 68 68 CD cord-022526-j9kg00qf 2142 2 Most most RBS cord-022526-j9kg00qf 2142 3 importantly importantly RB cord-022526-j9kg00qf 2142 4 for for IN cord-022526-j9kg00qf 2142 5 the the DT cord-022526-j9kg00qf 2142 6 treatment treatment NN cord-022526-j9kg00qf 2142 7 of of IN cord-022526-j9kg00qf 2142 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2142 9 , , , cord-022526-j9kg00qf 2142 10 ω-3 ω-3 CD cord-022526-j9kg00qf 2142 11 fatty fatty JJ cord-022526-j9kg00qf 2142 12 acid acid NN cord-022526-j9kg00qf 2142 13 incorporation incorporation NN cord-022526-j9kg00qf 2142 14 into into IN cord-022526-j9kg00qf 2142 15 cell cell NN cord-022526-j9kg00qf 2142 16 membranes membrane NNS cord-022526-j9kg00qf 2142 17 decreases decrease VBZ cord-022526-j9kg00qf 2142 18 the the DT cord-022526-j9kg00qf 2142 19 availability availability NN cord-022526-j9kg00qf 2142 20 of of IN cord-022526-j9kg00qf 2142 21 arachidonic arachidonic JJ cord-022526-j9kg00qf 2142 22 acid acid NN cord-022526-j9kg00qf 2142 23 ( ( -LRB- cord-022526-j9kg00qf 2142 24 an an DT cord-022526-j9kg00qf 2142 25 ω-6 ω-6 NN cord-022526-j9kg00qf 2142 26 fatty fatty JJ cord-022526-j9kg00qf 2142 27 acid acid NN cord-022526-j9kg00qf 2142 28 ) ) -RRB- cord-022526-j9kg00qf 2142 29 for for IN cord-022526-j9kg00qf 2142 30 eicosanoid eicosanoid NNP cord-022526-j9kg00qf 2142 31 synthesis synthesis NNP cord-022526-j9kg00qf 2142 32 171 171 CD cord-022526-j9kg00qf 2142 33 and and CC cord-022526-j9kg00qf 2142 34 provides provide VBZ cord-022526-j9kg00qf 2142 35 alternative alternative JJ cord-022526-j9kg00qf 2142 36 substrates substrate NNS cord-022526-j9kg00qf 2142 37 . . . cord-022526-j9kg00qf 2143 1 Metabolism metabolism NN cord-022526-j9kg00qf 2143 2 of of IN cord-022526-j9kg00qf 2143 3 ω-3 ω-3 CD cord-022526-j9kg00qf 2143 4 fatty fatty JJ cord-022526-j9kg00qf 2143 5 acids acid NNS cord-022526-j9kg00qf 2143 6 via via IN cord-022526-j9kg00qf 2143 7 the the DT cord-022526-j9kg00qf 2143 8 COX COX NNP cord-022526-j9kg00qf 2143 9 and and CC cord-022526-j9kg00qf 2143 10 lipoxygenase lipoxygenase NNP cord-022526-j9kg00qf 2143 11 pathway pathway NN cord-022526-j9kg00qf 2143 12 leads lead VBZ cord-022526-j9kg00qf 2143 13 to to IN cord-022526-j9kg00qf 2143 14 the the DT cord-022526-j9kg00qf 2143 15 production production NN cord-022526-j9kg00qf 2143 16 of of IN cord-022526-j9kg00qf 2143 17 3-series 3-series CD cord-022526-j9kg00qf 2143 18 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 2143 19 and and CC cord-022526-j9kg00qf 2143 20 5-series 5-series CD cord-022526-j9kg00qf 2143 21 leukotrienes leukotriene NNS cord-022526-j9kg00qf 2143 22 , , , cord-022526-j9kg00qf 2143 23 which which WDT cord-022526-j9kg00qf 2143 24 have have VBP cord-022526-j9kg00qf 2143 25 less less JJR cord-022526-j9kg00qf 2143 26 biologic biologic JJ cord-022526-j9kg00qf 2143 27 activity activity NN cord-022526-j9kg00qf 2143 28 than than IN cord-022526-j9kg00qf 2143 29 their -PRON- PRP$ cord-022526-j9kg00qf 2143 30 2-series 2-series CD cord-022526-j9kg00qf 2143 31 and and CC cord-022526-j9kg00qf 2143 32 4-series 4-series CD cord-022526-j9kg00qf 2143 33 counterparts counterpart NNS cord-022526-j9kg00qf 2143 34 derived derive VBN cord-022526-j9kg00qf 2143 35 from from IN cord-022526-j9kg00qf 2143 36 arachidonic arachidonic JJ cord-022526-j9kg00qf 2143 37 acid acid NN cord-022526-j9kg00qf 2143 38 . . . cord-022526-j9kg00qf 2144 1 Aside aside RB cord-022526-j9kg00qf 2144 2 from from IN cord-022526-j9kg00qf 2144 3 these these DT cord-022526-j9kg00qf 2144 4 mechanisms mechanism NNS cord-022526-j9kg00qf 2144 5 , , , cord-022526-j9kg00qf 2144 6 ω-3 ω-3 CD cord-022526-j9kg00qf 2144 7 fatty fatty JJ cord-022526-j9kg00qf 2144 8 acids acid NNS cord-022526-j9kg00qf 2144 9 prevent prevent VBP cord-022526-j9kg00qf 2144 10 lipopolysaccharideinduced lipopolysaccharideinduced JJ cord-022526-j9kg00qf 2144 11 upregulation upregulation NN cord-022526-j9kg00qf 2144 12 of of IN cord-022526-j9kg00qf 2144 13 CD14 CD14 NNP cord-022526-j9kg00qf 2144 14 in in IN cord-022526-j9kg00qf 2144 15 monocytic monocytic JJ cord-022526-j9kg00qf 2144 16 cells cell NNS cord-022526-j9kg00qf 2144 17 and and CC cord-022526-j9kg00qf 2144 18 therefore therefore RB cord-022526-j9kg00qf 2144 19 may may MD cord-022526-j9kg00qf 2144 20 be be VB cord-022526-j9kg00qf 2144 21 able able JJ cord-022526-j9kg00qf 2144 22 to to TO cord-022526-j9kg00qf 2144 23 block block VB cord-022526-j9kg00qf 2144 24 transmembrane transmembrane NN cord-022526-j9kg00qf 2144 25 signaling signaling NN cord-022526-j9kg00qf 2144 26 of of IN cord-022526-j9kg00qf 2144 27 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2144 28 . . . cord-022526-j9kg00qf 2145 1 172 172 CD cord-022526-j9kg00qf 2145 2 Cells cell NNS cord-022526-j9kg00qf 2145 3 from from IN cord-022526-j9kg00qf 2145 4 horses horse NNS cord-022526-j9kg00qf 2145 5 given give VBN cord-022526-j9kg00qf 2145 6 linseed linseed NN cord-022526-j9kg00qf 2145 7 oil oil NN cord-022526-j9kg00qf 2145 8 ( ( -LRB- cord-022526-j9kg00qf 2145 9 high high JJ cord-022526-j9kg00qf 2145 10 in in IN cord-022526-j9kg00qf 2145 11 ω-3 ω-3 CD cord-022526-j9kg00qf 2145 12 fatty fatty JJ cord-022526-j9kg00qf 2145 13 acids acid NNS cord-022526-j9kg00qf 2145 14 ) ) -RRB- cord-022526-j9kg00qf 2145 15 for for IN cord-022526-j9kg00qf 2145 16 8 8 CD cord-022526-j9kg00qf 2145 17 weeks week NNS cord-022526-j9kg00qf 2145 18 before before IN cord-022526-j9kg00qf 2145 19 blood blood NN cord-022526-j9kg00qf 2145 20 collection collection NN cord-022526-j9kg00qf 2145 21 showed show VBD cord-022526-j9kg00qf 2145 22 significantly significantly RB cord-022526-j9kg00qf 2145 23 decreased decrease VBD cord-022526-j9kg00qf 2145 24 expression expression NN cord-022526-j9kg00qf 2145 25 of of IN cord-022526-j9kg00qf 2145 26 procoagulant procoagulant JJ cord-022526-j9kg00qf 2145 27 activity activity NN cord-022526-j9kg00qf 2145 28 , , , cord-022526-j9kg00qf 2145 29 TXB TXB NNP cord-022526-j9kg00qf 2145 30 2 2 CD cord-022526-j9kg00qf 2145 31 , , , cord-022526-j9kg00qf 2145 32 and and CC cord-022526-j9kg00qf 2145 33 TNF TNF NNP cord-022526-j9kg00qf 2145 34 in in IN cord-022526-j9kg00qf 2145 35 response response NN cord-022526-j9kg00qf 2145 36 to to IN cord-022526-j9kg00qf 2145 37 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2145 38 stimulation stimulation NN cord-022526-j9kg00qf 2145 39 . . . cord-022526-j9kg00qf 2146 1 173 173 CD cord-022526-j9kg00qf 2146 2 , , , cord-022526-j9kg00qf 2146 3 174 174 CD cord-022526-j9kg00qf 2147 1 In in IN cord-022526-j9kg00qf 2147 2 an an DT cord-022526-j9kg00qf 2147 3 in in IN cord-022526-j9kg00qf 2147 4 vivo vivo NNP cord-022526-j9kg00qf 2147 5 experimental experimental JJ cord-022526-j9kg00qf 2147 6 model model NN cord-022526-j9kg00qf 2147 7 of of IN cord-022526-j9kg00qf 2147 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2147 9 in in IN cord-022526-j9kg00qf 2147 10 horses horse NNS cord-022526-j9kg00qf 2147 11 , , , cord-022526-j9kg00qf 2147 12 treatment treatment NN cord-022526-j9kg00qf 2147 13 resulted result VBD cord-022526-j9kg00qf 2147 14 in in IN cord-022526-j9kg00qf 2147 15 prolonged prolong VBN cord-022526-j9kg00qf 2147 16 activated activate VBN cord-022526-j9kg00qf 2147 17 partial partial JJ cord-022526-j9kg00qf 2147 18 thromboplastin thromboplastin NN cord-022526-j9kg00qf 2147 19 time time NN cord-022526-j9kg00qf 2147 20 and and CC cord-022526-j9kg00qf 2147 21 whole whole JJ cord-022526-j9kg00qf 2147 22 blood blood NN cord-022526-j9kg00qf 2147 23 recalcification recalcification NN cord-022526-j9kg00qf 2147 24 time time NN cord-022526-j9kg00qf 2147 25 , , , cord-022526-j9kg00qf 2147 26 suggesting suggest VBG cord-022526-j9kg00qf 2147 27 an an DT cord-022526-j9kg00qf 2147 28 anticoagulant anticoagulant JJ cord-022526-j9kg00qf 2147 29 effect effect NN cord-022526-j9kg00qf 2148 1 ; ; : cord-022526-j9kg00qf 2148 2 however however RB cord-022526-j9kg00qf 2148 3 , , , cord-022526-j9kg00qf 2148 4 a a DT cord-022526-j9kg00qf 2148 5 significant significant JJ cord-022526-j9kg00qf 2148 6 beneficial beneficial JJ cord-022526-j9kg00qf 2148 7 effect effect NN cord-022526-j9kg00qf 2148 8 on on IN cord-022526-j9kg00qf 2148 9 clinical clinical JJ cord-022526-j9kg00qf 2148 10 response response NN cord-022526-j9kg00qf 2148 11 and and CC cord-022526-j9kg00qf 2148 12 serum serum NN cord-022526-j9kg00qf 2148 13 eicosanoid eicosanoid JJ cord-022526-j9kg00qf 2148 14 concentrations concentration NNS cord-022526-j9kg00qf 2148 15 was be VBD cord-022526-j9kg00qf 2148 16 not not RB cord-022526-j9kg00qf 2148 17 observed observe VBN cord-022526-j9kg00qf 2148 18 . . . cord-022526-j9kg00qf 2149 1 175 175 CD cord-022526-j9kg00qf 2150 1 Because because IN cord-022526-j9kg00qf 2150 2 dietary dietary JJ cord-022526-j9kg00qf 2150 3 addition addition NN cord-022526-j9kg00qf 2150 4 of of IN cord-022526-j9kg00qf 2150 5 ω-3 ω-3 CD cord-022526-j9kg00qf 2150 6 fatty fatty JJ cord-022526-j9kg00qf 2150 7 acids acid NNS cord-022526-j9kg00qf 2150 8 requires require VBZ cord-022526-j9kg00qf 2150 9 several several JJ cord-022526-j9kg00qf 2150 10 weeks week NNS cord-022526-j9kg00qf 2150 11 of of IN cord-022526-j9kg00qf 2150 12 treatment treatment NN cord-022526-j9kg00qf 2150 13 , , , cord-022526-j9kg00qf 2150 14 intravenous intravenous JJ cord-022526-j9kg00qf 2150 15 infusion infusion NN cord-022526-j9kg00qf 2150 16 was be VBD cord-022526-j9kg00qf 2150 17 evaluated evaluate VBN cord-022526-j9kg00qf 2150 18 and and CC cord-022526-j9kg00qf 2150 19 shown show VBN cord-022526-j9kg00qf 2150 20 to to TO cord-022526-j9kg00qf 2150 21 alter alter VB cord-022526-j9kg00qf 2150 22 the the DT cord-022526-j9kg00qf 2150 23 composition composition NN cord-022526-j9kg00qf 2150 24 of of IN cord-022526-j9kg00qf 2150 25 cell cell NN cord-022526-j9kg00qf 2150 26 membrane membrane NN cord-022526-j9kg00qf 2150 27 phospholipids phospholipid NNS cord-022526-j9kg00qf 2150 28 rapidly rapidly RB cord-022526-j9kg00qf 2150 29 . . . cord-022526-j9kg00qf 2151 1 176 176 CD cord-022526-j9kg00qf 2152 1 Further further JJ cord-022526-j9kg00qf 2152 2 evaluation evaluation NN cord-022526-j9kg00qf 2152 3 of of IN cord-022526-j9kg00qf 2152 4 this this DT cord-022526-j9kg00qf 2152 5 treatment treatment NN cord-022526-j9kg00qf 2152 6 for for IN cord-022526-j9kg00qf 2152 7 use use NN cord-022526-j9kg00qf 2152 8 in in IN cord-022526-j9kg00qf 2152 9 horses horse NNS cord-022526-j9kg00qf 2152 10 is be VBZ cord-022526-j9kg00qf 2152 11 necessary necessary JJ cord-022526-j9kg00qf 2152 12 before before IN cord-022526-j9kg00qf 2152 13 dosage dosage NN cord-022526-j9kg00qf 2152 14 recommendations recommendation NNS cord-022526-j9kg00qf 2152 15 can can MD cord-022526-j9kg00qf 2152 16 be be VB cord-022526-j9kg00qf 2152 17 made make VBN cord-022526-j9kg00qf 2152 18 . . . cord-022526-j9kg00qf 2153 1 Monoclonal monoclonal JJ cord-022526-j9kg00qf 2153 2 and and CC cord-022526-j9kg00qf 2153 3 polyclonal polyclonal JJ cord-022526-j9kg00qf 2153 4 antibodies antibody NNS cord-022526-j9kg00qf 2153 5 against against IN cord-022526-j9kg00qf 2153 6 equine equine JJ cord-022526-j9kg00qf 2153 7 TNF TNF NNP cord-022526-j9kg00qf 2153 8 have have VBP cord-022526-j9kg00qf 2153 9 been be VBN cord-022526-j9kg00qf 2153 10 evaluated evaluate VBN cord-022526-j9kg00qf 2153 11 . . . cord-022526-j9kg00qf 2154 1 [ [ -LRB- cord-022526-j9kg00qf 2154 2 177 177 CD cord-022526-j9kg00qf 2154 3 ] ] -RRB- cord-022526-j9kg00qf 2154 4 [ [ -LRB- cord-022526-j9kg00qf 2154 5 178 178 CD cord-022526-j9kg00qf 2154 6 ] ] -RRB- cord-022526-j9kg00qf 2154 7 [ [ -LRB- cord-022526-j9kg00qf 2154 8 179 179 CD cord-022526-j9kg00qf 2154 9 ] ] -RRB- cord-022526-j9kg00qf 2154 10 Administration Administration NNP cord-022526-j9kg00qf 2154 11 of of IN cord-022526-j9kg00qf 2154 12 a a DT cord-022526-j9kg00qf 2154 13 monoclonal monoclonal JJ cord-022526-j9kg00qf 2154 14 antibody antibody NN cord-022526-j9kg00qf 2154 15 preparation preparation NN cord-022526-j9kg00qf 2154 16 before before IN cord-022526-j9kg00qf 2154 17 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2154 18 infusion infusion NN cord-022526-j9kg00qf 2154 19 resulted result VBD cord-022526-j9kg00qf 2154 20 in in IN cord-022526-j9kg00qf 2154 21 significantly significantly RB cord-022526-j9kg00qf 2154 22 reduced reduce VBN cord-022526-j9kg00qf 2154 23 plasma plasma NN cord-022526-j9kg00qf 2154 24 TNF tnf NN cord-022526-j9kg00qf 2154 25 - - HYPH cord-022526-j9kg00qf 2154 26 activity activity NN cord-022526-j9kg00qf 2154 27 , , , cord-022526-j9kg00qf 2154 28 improved improve VBD cord-022526-j9kg00qf 2154 29 clinical clinical JJ cord-022526-j9kg00qf 2154 30 abnormality abnormality NN cord-022526-j9kg00qf 2154 31 scores score NNS cord-022526-j9kg00qf 2154 32 , , , cord-022526-j9kg00qf 2154 33 lower low JJR cord-022526-j9kg00qf 2154 34 heart heart NN cord-022526-j9kg00qf 2154 35 rate rate NN cord-022526-j9kg00qf 2154 36 , , , cord-022526-j9kg00qf 2154 37 and and CC cord-022526-j9kg00qf 2154 38 higher high JJR cord-022526-j9kg00qf 2154 39 leukocyte leukocyte NN cord-022526-j9kg00qf 2154 40 count count NN cord-022526-j9kg00qf 2154 41 compared compare VBN cord-022526-j9kg00qf 2154 42 with with IN cord-022526-j9kg00qf 2154 43 controls control NNS cord-022526-j9kg00qf 2154 44 . . . cord-022526-j9kg00qf 2155 1 178 178 CD cord-022526-j9kg00qf 2156 1 Furthermore furthermore RB cord-022526-j9kg00qf 2156 2 , , , cord-022526-j9kg00qf 2156 3 plasma plasma NN cord-022526-j9kg00qf 2156 4 concentrations concentration NNS cord-022526-j9kg00qf 2156 5 of of IN cord-022526-j9kg00qf 2156 6 lactate lactate NN cord-022526-j9kg00qf 2156 7 and and CC cord-022526-j9kg00qf 2156 8 6-keto 6-keto CD cord-022526-j9kg00qf 2156 9 - - HYPH cord-022526-j9kg00qf 2156 10 PGF PGF NNP cord-022526-j9kg00qf 2156 11 1α 1α CD cord-022526-j9kg00qf 2156 12 were be VBD cord-022526-j9kg00qf 2156 13 reduced reduce VBN cord-022526-j9kg00qf 2156 14 significantly significantly RB cord-022526-j9kg00qf 2156 15 , , , cord-022526-j9kg00qf 2156 16 whereas whereas IN cord-022526-j9kg00qf 2156 17 TXA TXA NNP cord-022526-j9kg00qf 2156 18 2 2 CD cord-022526-j9kg00qf 2156 19 production production NN cord-022526-j9kg00qf 2156 20 was be VBD cord-022526-j9kg00qf 2156 21 not not RB cord-022526-j9kg00qf 2156 22 affected affect VBN cord-022526-j9kg00qf 2156 23 . . . cord-022526-j9kg00qf 2157 1 177 177 CD cord-022526-j9kg00qf 2158 1 In in IN cord-022526-j9kg00qf 2158 2 another another DT cord-022526-j9kg00qf 2158 3 study study NN cord-022526-j9kg00qf 2158 4 , , , cord-022526-j9kg00qf 2158 5 179 179 CD cord-022526-j9kg00qf 2158 6 administration administration NN cord-022526-j9kg00qf 2158 7 of of IN cord-022526-j9kg00qf 2158 8 a a DT cord-022526-j9kg00qf 2158 9 rabbit rabbit NN cord-022526-j9kg00qf 2158 10 polyclonal polyclonal JJ cord-022526-j9kg00qf 2158 11 antibody antibody NN cord-022526-j9kg00qf 2158 12 against against IN cord-022526-j9kg00qf 2158 13 recombinant recombinant JJ cord-022526-j9kg00qf 2158 14 human human JJ cord-022526-j9kg00qf 2158 15 TNF TNF NNP cord-022526-j9kg00qf 2158 16 was be VBD cord-022526-j9kg00qf 2158 17 unable unable JJ cord-022526-j9kg00qf 2158 18 to to TO cord-022526-j9kg00qf 2158 19 improve improve VB cord-022526-j9kg00qf 2158 20 clinical clinical JJ cord-022526-j9kg00qf 2158 21 and and CC cord-022526-j9kg00qf 2158 22 hematologic hematologic JJ cord-022526-j9kg00qf 2158 23 parameters parameter NNS cord-022526-j9kg00qf 2158 24 when when WRB cord-022526-j9kg00qf 2158 25 given give VBN cord-022526-j9kg00qf 2158 26 shortly shortly RB cord-022526-j9kg00qf 2158 27 ( ( -LRB- cord-022526-j9kg00qf 2158 28 15 15 CD cord-022526-j9kg00qf 2158 29 minutes minute NNS cord-022526-j9kg00qf 2158 30 ) ) -RRB- cord-022526-j9kg00qf 2158 31 after after IN cord-022526-j9kg00qf 2158 32 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2158 33 infusion infusion NN cord-022526-j9kg00qf 2158 34 , , , cord-022526-j9kg00qf 2158 35 although although IN cord-022526-j9kg00qf 2158 36 inhibition inhibition NN cord-022526-j9kg00qf 2158 37 of of IN cord-022526-j9kg00qf 2158 38 TNF TNF NNP cord-022526-j9kg00qf 2158 39 activity activity NN cord-022526-j9kg00qf 2158 40 was be VBD cord-022526-j9kg00qf 2158 41 present present JJ cord-022526-j9kg00qf 2158 42 in in IN cord-022526-j9kg00qf 2158 43 vitro vitro FW cord-022526-j9kg00qf 2158 44 . . . cord-022526-j9kg00qf 2159 1 179 179 CD cord-022526-j9kg00qf 2159 2 , , , cord-022526-j9kg00qf 2159 3 180 180 CD cord-022526-j9kg00qf 2159 4 Findings finding NNS cord-022526-j9kg00qf 2159 5 in in IN cord-022526-j9kg00qf 2159 6 horses horse NNS cord-022526-j9kg00qf 2159 7 are be VBP cord-022526-j9kg00qf 2159 8 in in IN cord-022526-j9kg00qf 2159 9 agreement agreement NN cord-022526-j9kg00qf 2159 10 with with IN cord-022526-j9kg00qf 2159 11 studies study NNS cord-022526-j9kg00qf 2159 12 in in IN cord-022526-j9kg00qf 2159 13 other other JJ cord-022526-j9kg00qf 2159 14 species specie NNS cord-022526-j9kg00qf 2159 15 and and CC cord-022526-j9kg00qf 2159 16 suggest suggest VBP cord-022526-j9kg00qf 2159 17 that that IN cord-022526-j9kg00qf 2159 18 beneficial beneficial JJ cord-022526-j9kg00qf 2159 19 effects effect NNS cord-022526-j9kg00qf 2159 20 of of IN cord-022526-j9kg00qf 2159 21 TNF TNF NNP cord-022526-j9kg00qf 2159 22 inhibition inhibition NN cord-022526-j9kg00qf 2159 23 may may MD cord-022526-j9kg00qf 2159 24 be be VB cord-022526-j9kg00qf 2159 25 limited limit VBN cord-022526-j9kg00qf 2159 26 to to IN cord-022526-j9kg00qf 2159 27 administration administration NN cord-022526-j9kg00qf 2159 28 before before IN cord-022526-j9kg00qf 2159 29 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2159 30 exposure exposure NN cord-022526-j9kg00qf 2159 31 . . . cord-022526-j9kg00qf 2160 1 Widespread widespread JJ cord-022526-j9kg00qf 2160 2 clinical clinical JJ cord-022526-j9kg00qf 2160 3 use use NN cord-022526-j9kg00qf 2160 4 therefore therefore RB cord-022526-j9kg00qf 2160 5 is be VBZ cord-022526-j9kg00qf 2160 6 unlikely unlikely JJ cord-022526-j9kg00qf 2160 7 to to TO cord-022526-j9kg00qf 2160 8 become become VB cord-022526-j9kg00qf 2160 9 feasible feasible JJ cord-022526-j9kg00qf 2160 10 . . . cord-022526-j9kg00qf 2161 1 Clinical clinical JJ cord-022526-j9kg00qf 2161 2 trials trial NNS cord-022526-j9kg00qf 2161 3 in in IN cord-022526-j9kg00qf 2161 4 human human JJ cord-022526-j9kg00qf 2161 5 patients patient NNS cord-022526-j9kg00qf 2161 6 have have VBP cord-022526-j9kg00qf 2161 7 not not RB cord-022526-j9kg00qf 2161 8 shown show VBN cord-022526-j9kg00qf 2161 9 significant significant JJ cord-022526-j9kg00qf 2161 10 benefits benefit NNS cord-022526-j9kg00qf 2161 11 of of IN cord-022526-j9kg00qf 2161 12 TNF TNF NNP cord-022526-j9kg00qf 2161 13 antibody antibody NN cord-022526-j9kg00qf 2161 14 treatment treatment NN cord-022526-j9kg00qf 2161 15 . . . cord-022526-j9kg00qf 2162 1 181 181 CD cord-022526-j9kg00qf 2162 2 , , , cord-022526-j9kg00qf 2162 3 182 182 CD cord-022526-j9kg00qf 2162 4 _SP cord-022526-j9kg00qf 2162 5 The the DT cord-022526-j9kg00qf 2162 6 effects effect NNS cord-022526-j9kg00qf 2162 7 of of IN cord-022526-j9kg00qf 2162 8 selective selective JJ cord-022526-j9kg00qf 2162 9 PAF PAF NNP cord-022526-j9kg00qf 2162 10 receptor receptor NN cord-022526-j9kg00qf 2162 11 antagonists antagonist NNS cord-022526-j9kg00qf 2162 12 have have VBP cord-022526-j9kg00qf 2162 13 been be VBN cord-022526-j9kg00qf 2162 14 evaluated evaluate VBN cord-022526-j9kg00qf 2162 15 . . . cord-022526-j9kg00qf 2163 1 PAF PAF NNP cord-022526-j9kg00qf 2163 2 is be VBZ cord-022526-j9kg00qf 2163 3 implicated implicate VBN cord-022526-j9kg00qf 2163 4 in in IN cord-022526-j9kg00qf 2163 5 the the DT cord-022526-j9kg00qf 2163 6 development development NN cord-022526-j9kg00qf 2163 7 of of IN cord-022526-j9kg00qf 2163 8 systemic systemic JJ cord-022526-j9kg00qf 2163 9 hypotension hypotension NN cord-022526-j9kg00qf 2163 10 , , , cord-022526-j9kg00qf 2163 11 183 183 CD cord-022526-j9kg00qf 2163 12 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2163 13 - - HYPH cord-022526-j9kg00qf 2163 14 induced induce VBN cord-022526-j9kg00qf 2163 15 platelet platelet NN cord-022526-j9kg00qf 2163 16 aggregation aggregation NN cord-022526-j9kg00qf 2163 17 , , , cord-022526-j9kg00qf 2163 18 184 184 CD cord-022526-j9kg00qf 2163 19 ileus ileus NNP cord-022526-j9kg00qf 2163 20 , , , cord-022526-j9kg00qf 2163 21 185 185 CD cord-022526-j9kg00qf 2163 22 and and CC cord-022526-j9kg00qf 2163 23 increased increase VBD cord-022526-j9kg00qf 2163 24 vascular vascular JJ cord-022526-j9kg00qf 2163 25 permeability permeability NN cord-022526-j9kg00qf 2163 26 186 186 CD cord-022526-j9kg00qf 2163 27 and and CC cord-022526-j9kg00qf 2163 28 may may MD cord-022526-j9kg00qf 2163 29 mediate mediate VB cord-022526-j9kg00qf 2163 30 recruitment recruitment NN cord-022526-j9kg00qf 2163 31 of of IN cord-022526-j9kg00qf 2163 32 leukocytes leukocyte NNS cord-022526-j9kg00qf 2163 33 to to IN cord-022526-j9kg00qf 2163 34 inflamed inflamed JJ cord-022526-j9kg00qf 2163 35 tissues tissue NNS cord-022526-j9kg00qf 2163 36 . . . cord-022526-j9kg00qf 2164 1 187 187 CD cord-022526-j9kg00qf 2164 2 , , , cord-022526-j9kg00qf 2164 3 188 188 CD cord-022526-j9kg00qf 2164 4 A a DT cord-022526-j9kg00qf 2164 5 study study NN cord-022526-j9kg00qf 2164 6 in in IN cord-022526-j9kg00qf 2164 7 horses horse NNS cord-022526-j9kg00qf 2164 8 using use VBG cord-022526-j9kg00qf 2164 9 the the DT cord-022526-j9kg00qf 2164 10 PAF PAF NNP cord-022526-j9kg00qf 2164 11 receptor receptor NN cord-022526-j9kg00qf 2164 12 antagonist antagonist NN cord-022526-j9kg00qf 2164 13 SRI SRI NNP cord-022526-j9kg00qf 2164 14 63 63 CD cord-022526-j9kg00qf 2164 15 - - SYM cord-022526-j9kg00qf 2164 16 441 441 CD cord-022526-j9kg00qf 2164 17 before before IN cord-022526-j9kg00qf 2164 18 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2164 19 infusion infusion NN cord-022526-j9kg00qf 2164 20 showed show VBD cord-022526-j9kg00qf 2164 21 significant significant JJ cord-022526-j9kg00qf 2164 22 decreases decrease NNS cord-022526-j9kg00qf 2164 23 in in IN cord-022526-j9kg00qf 2164 24 heart heart NN cord-022526-j9kg00qf 2164 25 rate rate NN cord-022526-j9kg00qf 2164 26 and and CC cord-022526-j9kg00qf 2164 27 shorter short JJR cord-022526-j9kg00qf 2164 28 elevation elevation NN cord-022526-j9kg00qf 2164 29 of of IN cord-022526-j9kg00qf 2164 30 lactate lactate NN cord-022526-j9kg00qf 2164 31 concentrations concentration NNS cord-022526-j9kg00qf 2164 32 in in IN cord-022526-j9kg00qf 2164 33 response response NN cord-022526-j9kg00qf 2164 34 to to IN cord-022526-j9kg00qf 2164 35 the the DT cord-022526-j9kg00qf 2164 36 treatment treatment NN cord-022526-j9kg00qf 2164 37 . . . cord-022526-j9kg00qf 2165 1 Although although IN cord-022526-j9kg00qf 2165 2 not not RB cord-022526-j9kg00qf 2165 3 statistically statistically RB cord-022526-j9kg00qf 2165 4 significant significant JJ cord-022526-j9kg00qf 2165 5 , , , cord-022526-j9kg00qf 2165 6 additional additional JJ cord-022526-j9kg00qf 2165 7 beneficial beneficial JJ cord-022526-j9kg00qf 2165 8 effects effect NNS cord-022526-j9kg00qf 2165 9 included include VBN cord-022526-j9kg00qf 2165 10 delayed delay VBN cord-022526-j9kg00qf 2165 11 onset onset NN cord-022526-j9kg00qf 2165 12 of of IN cord-022526-j9kg00qf 2165 13 fever fever NN cord-022526-j9kg00qf 2165 14 , , , cord-022526-j9kg00qf 2165 15 a a DT cord-022526-j9kg00qf 2165 16 shortened shorten VBN cord-022526-j9kg00qf 2165 17 period period NN cord-022526-j9kg00qf 2165 18 of of IN cord-022526-j9kg00qf 2165 19 neutropenia neutropenia NN cord-022526-j9kg00qf 2165 20 , , , cord-022526-j9kg00qf 2165 21 and and CC cord-022526-j9kg00qf 2165 22 reduced reduce VBN cord-022526-j9kg00qf 2165 23 maximal maximal JJ cord-022526-j9kg00qf 2165 24 platelet platelet NN cord-022526-j9kg00qf 2165 25 aggregation aggregation NN cord-022526-j9kg00qf 2165 26 . . . cord-022526-j9kg00qf 2166 1 189 189 CD cord-022526-j9kg00qf 2167 1 Whenever whenever WRB cord-022526-j9kg00qf 2167 2 possible possible JJ cord-022526-j9kg00qf 2167 3 , , , cord-022526-j9kg00qf 2167 4 the the DT cord-022526-j9kg00qf 2167 5 clinician clinician NN cord-022526-j9kg00qf 2167 6 should should MD cord-022526-j9kg00qf 2167 7 correct correct VB cord-022526-j9kg00qf 2167 8 volume volume NN cord-022526-j9kg00qf 2167 9 and and CC cord-022526-j9kg00qf 2167 10 electrolyte electrolyte JJ cord-022526-j9kg00qf 2167 11 deficits deficit NNS cord-022526-j9kg00qf 2167 12 , , , cord-022526-j9kg00qf 2167 13 or or CC cord-022526-j9kg00qf 2167 14 at at IN cord-022526-j9kg00qf 2167 15 least least JJS cord-022526-j9kg00qf 2167 16 improve improve VB cord-022526-j9kg00qf 2167 17 them -PRON- PRP cord-022526-j9kg00qf 2167 18 , , , cord-022526-j9kg00qf 2167 19 before before IN cord-022526-j9kg00qf 2167 20 anesthetizing anesthetize VBG cord-022526-j9kg00qf 2167 21 a a DT cord-022526-j9kg00qf 2167 22 patient patient NN cord-022526-j9kg00qf 2167 23 for for IN cord-022526-j9kg00qf 2167 24 a a DT cord-022526-j9kg00qf 2167 25 surgical surgical JJ cord-022526-j9kg00qf 2167 26 procedure procedure NN cord-022526-j9kg00qf 2167 27 . . . cord-022526-j9kg00qf 2168 1 For for IN cord-022526-j9kg00qf 2168 2 initial initial JJ cord-022526-j9kg00qf 2168 3 resuscitation resuscitation NN cord-022526-j9kg00qf 2168 4 , , , cord-022526-j9kg00qf 2168 5 polyionic polyionic NNP cord-022526-j9kg00qf 2168 6 solutions solution NNS cord-022526-j9kg00qf 2168 7 such such JJ cord-022526-j9kg00qf 2168 8 as as IN cord-022526-j9kg00qf 2168 9 lactated lactate VBN cord-022526-j9kg00qf 2168 10 Ringer Ringer NNP cord-022526-j9kg00qf 2168 11 's 's POS cord-022526-j9kg00qf 2168 12 solution solution NN cord-022526-j9kg00qf 2168 13 given give VBN cord-022526-j9kg00qf 2168 14 at at IN cord-022526-j9kg00qf 2168 15 rates rate NNS cord-022526-j9kg00qf 2168 16 of of IN cord-022526-j9kg00qf 2168 17 10 10 CD cord-022526-j9kg00qf 2168 18 to to TO cord-022526-j9kg00qf 2168 19 20 20 CD cord-022526-j9kg00qf 2168 20 ml ml NNS cord-022526-j9kg00qf 2168 21 / / SYM cord-022526-j9kg00qf 2168 22 kg kg NNP cord-022526-j9kg00qf 2168 23 / / SYM cord-022526-j9kg00qf 2168 24 hr hr NNP cord-022526-j9kg00qf 2168 25 are be VBP cord-022526-j9kg00qf 2168 26 appropriate appropriate JJ cord-022526-j9kg00qf 2168 27 . . . cord-022526-j9kg00qf 2169 1 Patients patient NNS cord-022526-j9kg00qf 2169 2 with with IN cord-022526-j9kg00qf 2169 3 severe severe JJ cord-022526-j9kg00qf 2169 4 hypovolemia hypovolemia NN cord-022526-j9kg00qf 2169 5 and and CC cord-022526-j9kg00qf 2169 6 shock shock NN cord-022526-j9kg00qf 2169 7 may may MD cord-022526-j9kg00qf 2169 8 require require VB cord-022526-j9kg00qf 2169 9 higher high JJR cord-022526-j9kg00qf 2169 10 fluid fluid JJ cord-022526-j9kg00qf 2169 11 volumes volume NNS cord-022526-j9kg00qf 2169 12 . . . cord-022526-j9kg00qf 2170 1 A a DT cord-022526-j9kg00qf 2170 2 viable viable JJ cord-022526-j9kg00qf 2170 3 alternative alternative NN cord-022526-j9kg00qf 2170 4 to to IN cord-022526-j9kg00qf 2170 5 large large JJ cord-022526-j9kg00qf 2170 6 - - HYPH cord-022526-j9kg00qf 2170 7 volume volume NN cord-022526-j9kg00qf 2170 8 resuscitation resuscitation NN cord-022526-j9kg00qf 2170 9 with with IN cord-022526-j9kg00qf 2170 10 isotonic isotonic JJ cord-022526-j9kg00qf 2170 11 fluids fluid NNS cord-022526-j9kg00qf 2170 12 is be VBZ cord-022526-j9kg00qf 2170 13 the the DT cord-022526-j9kg00qf 2170 14 use use NN cord-022526-j9kg00qf 2170 15 of of IN cord-022526-j9kg00qf 2170 16 small small JJ cord-022526-j9kg00qf 2170 17 volumes volume NNS cord-022526-j9kg00qf 2170 18 of of IN cord-022526-j9kg00qf 2170 19 hypertonic hypertonic JJ cord-022526-j9kg00qf 2170 20 solutions solution NNS cord-022526-j9kg00qf 2170 21 , , , cord-022526-j9kg00qf 2170 22 which which WDT cord-022526-j9kg00qf 2170 23 transiently transiently RB cord-022526-j9kg00qf 2170 24 raise raise VBP cord-022526-j9kg00qf 2170 25 plasma plasma NN cord-022526-j9kg00qf 2170 26 osmolality osmolality NN cord-022526-j9kg00qf 2170 27 , , , cord-022526-j9kg00qf 2170 28 thereby thereby RB cord-022526-j9kg00qf 2170 29 causing cause VBG cord-022526-j9kg00qf 2170 30 a a DT cord-022526-j9kg00qf 2170 31 fluid fluid JJ cord-022526-j9kg00qf 2170 32 shift shift NN cord-022526-j9kg00qf 2170 33 from from IN cord-022526-j9kg00qf 2170 34 the the DT cord-022526-j9kg00qf 2170 35 interstitial interstitial JJ cord-022526-j9kg00qf 2170 36 space space NN cord-022526-j9kg00qf 2170 37 into into IN cord-022526-j9kg00qf 2170 38 the the DT cord-022526-j9kg00qf 2170 39 vasculature vasculature NN cord-022526-j9kg00qf 2170 40 and and CC cord-022526-j9kg00qf 2170 41 rapidly rapidly RB cord-022526-j9kg00qf 2170 42 restoring restore VBG cord-022526-j9kg00qf 2170 43 circulating circulate VBG cord-022526-j9kg00qf 2170 44 volume volume NN cord-022526-j9kg00qf 2170 45 . . . cord-022526-j9kg00qf 2171 1 Hypertonic Hypertonic NNP cord-022526-j9kg00qf 2171 2 saline saline NN cord-022526-j9kg00qf 2171 3 solution solution NN cord-022526-j9kg00qf 2171 4 ( ( -LRB- cord-022526-j9kg00qf 2171 5 7.5 7.5 CD cord-022526-j9kg00qf 2171 6 % % NN cord-022526-j9kg00qf 2171 7 sodium sodium NN cord-022526-j9kg00qf 2171 8 chloride chloride NN cord-022526-j9kg00qf 2171 9 ) ) -RRB- cord-022526-j9kg00qf 2171 10 is be VBZ cord-022526-j9kg00qf 2171 11 the the DT cord-022526-j9kg00qf 2171 12 most most RBS cord-022526-j9kg00qf 2171 13 commonly commonly RB cord-022526-j9kg00qf 2171 14 used use VBN cord-022526-j9kg00qf 2171 15 hypertonic hypertonic JJ cord-022526-j9kg00qf 2171 16 solution solution NN cord-022526-j9kg00qf 2171 17 and and CC cord-022526-j9kg00qf 2171 18 has have VBZ cord-022526-j9kg00qf 2171 19 been be VBN cord-022526-j9kg00qf 2171 20 shown show VBN cord-022526-j9kg00qf 2171 21 to to TO cord-022526-j9kg00qf 2171 22 have have VB cord-022526-j9kg00qf 2171 23 beneficial beneficial JJ cord-022526-j9kg00qf 2171 24 effects effect NNS cord-022526-j9kg00qf 2171 25 in in IN cord-022526-j9kg00qf 2171 26 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 2171 27 horses horse NNS cord-022526-j9kg00qf 2171 28 . . . cord-022526-j9kg00qf 2172 1 190 190 CD cord-022526-j9kg00qf 2172 2 A a DT cord-022526-j9kg00qf 2172 3 dose dose NN cord-022526-j9kg00qf 2172 4 of of IN cord-022526-j9kg00qf 2172 5 4 4 CD cord-022526-j9kg00qf 2172 6 ml ml NNS cord-022526-j9kg00qf 2172 7 / / SYM cord-022526-j9kg00qf 2172 8 kg kg NN cord-022526-j9kg00qf 2172 9 is be VBZ cord-022526-j9kg00qf 2172 10 recommended recommend VBN cord-022526-j9kg00qf 2172 11 , , , cord-022526-j9kg00qf 2172 12 which which WDT cord-022526-j9kg00qf 2172 13 one one PRP cord-022526-j9kg00qf 2172 14 should should MD cord-022526-j9kg00qf 2172 15 give give VB cord-022526-j9kg00qf 2172 16 as as IN cord-022526-j9kg00qf 2172 17 a a DT cord-022526-j9kg00qf 2172 18 bolus bolus NN cord-022526-j9kg00qf 2172 19 infusion infusion NN cord-022526-j9kg00qf 2172 20 over over IN cord-022526-j9kg00qf 2172 21 10 10 CD cord-022526-j9kg00qf 2172 22 to to TO cord-022526-j9kg00qf 2172 23 15 15 CD cord-022526-j9kg00qf 2172 24 minutes minute NNS cord-022526-j9kg00qf 2172 25 , , , cord-022526-j9kg00qf 2172 26 followed follow VBN cord-022526-j9kg00qf 2172 27 by by IN cord-022526-j9kg00qf 2172 28 administration administration NN cord-022526-j9kg00qf 2172 29 of of IN cord-022526-j9kg00qf 2172 30 an an DT cord-022526-j9kg00qf 2172 31 isotonic isotonic JJ cord-022526-j9kg00qf 2172 32 solution solution NN cord-022526-j9kg00qf 2172 33 to to TO cord-022526-j9kg00qf 2172 34 restore restore VB cord-022526-j9kg00qf 2172 35 total total JJ cord-022526-j9kg00qf 2172 36 body body NN cord-022526-j9kg00qf 2172 37 fluid fluid NN cord-022526-j9kg00qf 2172 38 volume volume NN cord-022526-j9kg00qf 2172 39 . . . cord-022526-j9kg00qf 2173 1 One one PRP cord-022526-j9kg00qf 2173 2 should should MD cord-022526-j9kg00qf 2173 3 use use VB cord-022526-j9kg00qf 2173 4 hypertonic hypertonic JJ cord-022526-j9kg00qf 2173 5 saline saline NN cord-022526-j9kg00qf 2173 6 with with IN cord-022526-j9kg00qf 2173 7 caution caution NN cord-022526-j9kg00qf 2173 8 in in IN cord-022526-j9kg00qf 2173 9 patients patient NNS cord-022526-j9kg00qf 2173 10 with with IN cord-022526-j9kg00qf 2173 11 sodium sodium NN cord-022526-j9kg00qf 2173 12 and/or and/or CC cord-022526-j9kg00qf 2173 13 chloride chloride NN cord-022526-j9kg00qf 2173 14 derangements derangement NNS cord-022526-j9kg00qf 2173 15 and and CC cord-022526-j9kg00qf 2173 16 should should MD cord-022526-j9kg00qf 2173 17 monitor monitor VB cord-022526-j9kg00qf 2173 18 serum serum NN cord-022526-j9kg00qf 2173 19 electrolyte electrolyte NN cord-022526-j9kg00qf 2173 20 concentrations concentration NNS cord-022526-j9kg00qf 2173 21 in in IN cord-022526-j9kg00qf 2173 22 the the DT cord-022526-j9kg00qf 2173 23 case case NN cord-022526-j9kg00qf 2173 24 of of IN cord-022526-j9kg00qf 2173 25 repeated repeat VBN cord-022526-j9kg00qf 2173 26 administration administration NN cord-022526-j9kg00qf 2173 27 . . . cord-022526-j9kg00qf 2174 1 Improvement improvement NN cord-022526-j9kg00qf 2174 2 of of IN cord-022526-j9kg00qf 2174 3 the the DT cord-022526-j9kg00qf 2174 4 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 2174 5 status status NN cord-022526-j9kg00qf 2174 6 in in IN cord-022526-j9kg00qf 2174 7 response response NN cord-022526-j9kg00qf 2174 8 to to IN cord-022526-j9kg00qf 2174 9 fluid fluid JJ cord-022526-j9kg00qf 2174 10 therapy therapy NN cord-022526-j9kg00qf 2174 11 is be VBZ cord-022526-j9kg00qf 2174 12 indicated indicate VBN cord-022526-j9kg00qf 2174 13 by by IN cord-022526-j9kg00qf 2174 14 normalization normalization NN cord-022526-j9kg00qf 2174 15 of of IN cord-022526-j9kg00qf 2174 16 heart heart NN cord-022526-j9kg00qf 2174 17 rate rate NN cord-022526-j9kg00qf 2174 18 , , , cord-022526-j9kg00qf 2174 19 mucous mucous JJ cord-022526-j9kg00qf 2174 20 membrane membrane NN cord-022526-j9kg00qf 2174 21 color color NN cord-022526-j9kg00qf 2174 22 , , , cord-022526-j9kg00qf 2174 23 and and CC cord-022526-j9kg00qf 2174 24 capillary capillary JJ cord-022526-j9kg00qf 2174 25 refill refill NN cord-022526-j9kg00qf 2174 26 time time NN cord-022526-j9kg00qf 2174 27 . . . cord-022526-j9kg00qf 2175 1 Failure failure NN cord-022526-j9kg00qf 2175 2 of of IN cord-022526-j9kg00qf 2175 3 urination urination NN cord-022526-j9kg00qf 2175 4 to to TO cord-022526-j9kg00qf 2175 5 occur occur VB cord-022526-j9kg00qf 2175 6 despite despite IN cord-022526-j9kg00qf 2175 7 appropriate appropriate JJ cord-022526-j9kg00qf 2175 8 fluid fluid JJ cord-022526-j9kg00qf 2175 9 resuscitation resuscitation NN cord-022526-j9kg00qf 2175 10 should should MD cord-022526-j9kg00qf 2175 11 result result VB cord-022526-j9kg00qf 2175 12 in in IN cord-022526-j9kg00qf 2175 13 critical critical JJ cord-022526-j9kg00qf 2175 14 evaluation evaluation NN cord-022526-j9kg00qf 2175 15 of of IN cord-022526-j9kg00qf 2175 16 renal renal JJ cord-022526-j9kg00qf 2175 17 function function NN cord-022526-j9kg00qf 2175 18 . . . cord-022526-j9kg00qf 2176 1 Once once IN cord-022526-j9kg00qf 2176 2 one one PRP cord-022526-j9kg00qf 2176 3 has have VBZ cord-022526-j9kg00qf 2176 4 stabilized stabilize VBN cord-022526-j9kg00qf 2176 5 the the DT cord-022526-j9kg00qf 2176 6 patient patient NN cord-022526-j9kg00qf 2176 7 , , , cord-022526-j9kg00qf 2176 8 one one PRP cord-022526-j9kg00qf 2176 9 should should MD cord-022526-j9kg00qf 2176 10 choose choose VB cord-022526-j9kg00qf 2176 11 a a DT cord-022526-j9kg00qf 2176 12 maintenance maintenance NN cord-022526-j9kg00qf 2176 13 fluid fluid NN cord-022526-j9kg00qf 2176 14 rate rate NN cord-022526-j9kg00qf 2176 15 to to TO cord-022526-j9kg00qf 2176 16 maintain maintain VB cord-022526-j9kg00qf 2176 17 adequate adequate JJ cord-022526-j9kg00qf 2176 18 hydration hydration NN cord-022526-j9kg00qf 2176 19 and and CC cord-022526-j9kg00qf 2176 20 plasma plasma NN cord-022526-j9kg00qf 2176 21 volume volume NN cord-022526-j9kg00qf 2176 22 . . . cord-022526-j9kg00qf 2177 1 For for IN cord-022526-j9kg00qf 2177 2 adult adult NN cord-022526-j9kg00qf 2177 3 horses horse NNS cord-022526-j9kg00qf 2177 4 , , , cord-022526-j9kg00qf 2177 5 the the DT cord-022526-j9kg00qf 2177 6 maintenance maintenance NN cord-022526-j9kg00qf 2177 7 fluid fluid NN cord-022526-j9kg00qf 2177 8 rate rate NN cord-022526-j9kg00qf 2177 9 is be VBZ cord-022526-j9kg00qf 2177 10 approximately approximately RB cord-022526-j9kg00qf 2177 11 2 2 CD cord-022526-j9kg00qf 2177 12 ml ml NNS cord-022526-j9kg00qf 2177 13 / / SYM cord-022526-j9kg00qf 2177 14 kg kg NNP cord-022526-j9kg00qf 2177 15 / / SYM cord-022526-j9kg00qf 2177 16 hr hr NN cord-022526-j9kg00qf 2177 17 , , , cord-022526-j9kg00qf 2177 18 whereas whereas IN cord-022526-j9kg00qf 2177 19 neonatal neonatal JJ cord-022526-j9kg00qf 2177 20 foals foal NNS cord-022526-j9kg00qf 2177 21 that that WDT cord-022526-j9kg00qf 2177 22 are be VBP cord-022526-j9kg00qf 2177 23 not not RB cord-022526-j9kg00qf 2177 24 nursing nursing NN cord-022526-j9kg00qf 2177 25 may may MD cord-022526-j9kg00qf 2177 26 require require VB cord-022526-j9kg00qf 2177 27 larger large JJR cord-022526-j9kg00qf 2177 28 volumes volume NNS cord-022526-j9kg00qf 2177 29 ( ( -LRB- cord-022526-j9kg00qf 2177 30 4 4 CD cord-022526-j9kg00qf 2177 31 ml ml NN cord-022526-j9kg00qf 2177 32 / / SYM cord-022526-j9kg00qf 2177 33 kg kg NNP cord-022526-j9kg00qf 2177 34 / / SYM cord-022526-j9kg00qf 2177 35 hr hr NN cord-022526-j9kg00qf 2177 36 ) ) -RRB- cord-022526-j9kg00qf 2177 37 . . . cord-022526-j9kg00qf 2178 1 One one PRP cord-022526-j9kg00qf 2178 2 should should MD cord-022526-j9kg00qf 2178 3 monitor monitor VB cord-022526-j9kg00qf 2178 4 fluid fluid JJ cord-022526-j9kg00qf 2178 5 administration administration NN cord-022526-j9kg00qf 2178 6 carefully carefully RB cord-022526-j9kg00qf 2178 7 in in IN cord-022526-j9kg00qf 2178 8 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 2178 9 patients patient NNS cord-022526-j9kg00qf 2178 10 , , , cord-022526-j9kg00qf 2179 1 because because IN cord-022526-j9kg00qf 2179 2 lowered lowered JJ cord-022526-j9kg00qf 2179 3 plasma plasma NN cord-022526-j9kg00qf 2179 4 oncotic oncotic JJ cord-022526-j9kg00qf 2179 5 pressure pressure NN cord-022526-j9kg00qf 2179 6 caused cause VBN cord-022526-j9kg00qf 2179 7 by by IN cord-022526-j9kg00qf 2179 8 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 2179 9 along along IN cord-022526-j9kg00qf 2179 10 with with IN cord-022526-j9kg00qf 2179 11 an an DT cord-022526-j9kg00qf 2179 12 increased increase VBN cord-022526-j9kg00qf 2179 13 vascular vascular JJ cord-022526-j9kg00qf 2179 14 permeability permeability NN cord-022526-j9kg00qf 2179 15 increase increase VBP cord-022526-j9kg00qf 2179 16 the the DT cord-022526-j9kg00qf 2179 17 risk risk NN cord-022526-j9kg00qf 2179 18 of of IN cord-022526-j9kg00qf 2179 19 tissue tissue NN cord-022526-j9kg00qf 2179 20 edema edema NN cord-022526-j9kg00qf 2179 21 formation formation NN cord-022526-j9kg00qf 2179 22 . . . cord-022526-j9kg00qf 2180 1 Furthermore furthermore RB cord-022526-j9kg00qf 2180 2 , , , cord-022526-j9kg00qf 2180 3 a a DT cord-022526-j9kg00qf 2180 4 rapid rapid JJ cord-022526-j9kg00qf 2180 5 increase increase NN cord-022526-j9kg00qf 2180 6 in in IN cord-022526-j9kg00qf 2180 7 total total JJ cord-022526-j9kg00qf 2180 8 body body NN cord-022526-j9kg00qf 2180 9 fluid fluid NN cord-022526-j9kg00qf 2180 10 volume volume NN cord-022526-j9kg00qf 2180 11 may may MD cord-022526-j9kg00qf 2180 12 be be VB cord-022526-j9kg00qf 2180 13 detrimental detrimental JJ cord-022526-j9kg00qf 2180 14 in in IN cord-022526-j9kg00qf 2180 15 patients patient NNS cord-022526-j9kg00qf 2180 16 with with IN cord-022526-j9kg00qf 2180 17 compromised compromised JJ cord-022526-j9kg00qf 2180 18 cardiac cardiac JJ cord-022526-j9kg00qf 2180 19 and and CC cord-022526-j9kg00qf 2180 20 peripheral peripheral JJ cord-022526-j9kg00qf 2180 21 vasomotor vasomotor NN cord-022526-j9kg00qf 2180 22 function function NN cord-022526-j9kg00qf 2180 23 and and CC cord-022526-j9kg00qf 2180 24 may may MD cord-022526-j9kg00qf 2180 25 increase increase VB cord-022526-j9kg00qf 2180 26 the the DT cord-022526-j9kg00qf 2180 27 severity severity NN cord-022526-j9kg00qf 2180 28 of of IN cord-022526-j9kg00qf 2180 29 vascular vascular JJ cord-022526-j9kg00qf 2180 30 pooling pooling NN cord-022526-j9kg00qf 2180 31 in in IN cord-022526-j9kg00qf 2180 32 peripheral peripheral JJ cord-022526-j9kg00qf 2180 33 organs organ NNS cord-022526-j9kg00qf 2180 34 . . . cord-022526-j9kg00qf 2181 1 In in IN cord-022526-j9kg00qf 2181 2 these these DT cord-022526-j9kg00qf 2181 3 patients patient NNS cord-022526-j9kg00qf 2181 4 , , , cord-022526-j9kg00qf 2181 5 hypertonic hypertonic JJ cord-022526-j9kg00qf 2181 6 saline saline NN cord-022526-j9kg00qf 2181 7 or or CC cord-022526-j9kg00qf 2181 8 colloids colloid NNS cord-022526-j9kg00qf 2181 9 may may MD cord-022526-j9kg00qf 2181 10 be be VB cord-022526-j9kg00qf 2181 11 more more RBR cord-022526-j9kg00qf 2181 12 appropriate appropriate JJ cord-022526-j9kg00qf 2181 13 means mean NNS cord-022526-j9kg00qf 2181 14 of of IN cord-022526-j9kg00qf 2181 15 stabilization stabilization NN cord-022526-j9kg00qf 2181 16 than than IN cord-022526-j9kg00qf 2181 17 large large JJ cord-022526-j9kg00qf 2181 18 volumes volume NNS cord-022526-j9kg00qf 2181 19 of of IN cord-022526-j9kg00qf 2181 20 crystalloid crystalloid NNP cord-022526-j9kg00qf 2181 21 solutions solution NNS cord-022526-j9kg00qf 2181 22 . . . cord-022526-j9kg00qf 2182 1 Plasma plasma NN cord-022526-j9kg00qf 2182 2 is be VBZ cord-022526-j9kg00qf 2182 3 an an DT cord-022526-j9kg00qf 2182 4 ideal ideal JJ cord-022526-j9kg00qf 2182 5 colloid colloid NN cord-022526-j9kg00qf 2182 6 and and CC cord-022526-j9kg00qf 2182 7 should should MD cord-022526-j9kg00qf 2182 8 be be VB cord-022526-j9kg00qf 2182 9 administered administer VBN cord-022526-j9kg00qf 2182 10 to to TO cord-022526-j9kg00qf 2182 11 maintain maintain VB cord-022526-j9kg00qf 2182 12 a a DT cord-022526-j9kg00qf 2182 13 serum serum NN cord-022526-j9kg00qf 2182 14 total total JJ cord-022526-j9kg00qf 2182 15 protein protein NN cord-022526-j9kg00qf 2182 16 concentration concentration NN cord-022526-j9kg00qf 2182 17 above above IN cord-022526-j9kg00qf 2182 18 4.2 4.2 CD cord-022526-j9kg00qf 2182 19 g g NN cord-022526-j9kg00qf 2182 20 / / SYM cord-022526-j9kg00qf 2182 21 dl dl NN cord-022526-j9kg00qf 2182 22 . . . cord-022526-j9kg00qf 2183 1 121 121 CD cord-022526-j9kg00qf 2184 1 To to TO cord-022526-j9kg00qf 2184 2 raise raise VB cord-022526-j9kg00qf 2184 3 plasma plasma NN cord-022526-j9kg00qf 2184 4 protein protein NN cord-022526-j9kg00qf 2184 5 concentration concentration NN cord-022526-j9kg00qf 2184 6 and and CC cord-022526-j9kg00qf 2184 7 colloid colloid NN cord-022526-j9kg00qf 2184 8 osmotic osmotic JJ cord-022526-j9kg00qf 2184 9 pressure pressure NN cord-022526-j9kg00qf 2184 10 significantly significantly RB cord-022526-j9kg00qf 2184 11 , , , cord-022526-j9kg00qf 2184 12 however however RB cord-022526-j9kg00qf 2184 13 , , , cord-022526-j9kg00qf 2184 14 horses horse NNS cord-022526-j9kg00qf 2184 15 often often RB cord-022526-j9kg00qf 2184 16 require require VBP cord-022526-j9kg00qf 2184 17 large large JJ cord-022526-j9kg00qf 2184 18 volumes volume NNS cord-022526-j9kg00qf 2184 19 of of IN cord-022526-j9kg00qf 2184 20 plasma plasma NN cord-022526-j9kg00qf 2184 21 ( ( -LRB- cord-022526-j9kg00qf 2184 22 7 7 CD cord-022526-j9kg00qf 2184 23 to to TO cord-022526-j9kg00qf 2184 24 10 10 CD cord-022526-j9kg00qf 2184 25 L l NN cord-022526-j9kg00qf 2184 26 or or CC cord-022526-j9kg00qf 2184 27 more more JJR cord-022526-j9kg00qf 2184 28 in in IN cord-022526-j9kg00qf 2184 29 a a DT cord-022526-j9kg00qf 2184 30 450-kg 450-kg CD cord-022526-j9kg00qf 2184 31 horse horse NN cord-022526-j9kg00qf 2184 32 ) ) -RRB- cord-022526-j9kg00qf 2184 33 , , , cord-022526-j9kg00qf 2184 34 and and CC cord-022526-j9kg00qf 2184 35 one one PRP cord-022526-j9kg00qf 2184 36 should should MD cord-022526-j9kg00qf 2184 37 consider consider VB cord-022526-j9kg00qf 2184 38 alternative alternative JJ cord-022526-j9kg00qf 2184 39 colloids colloid NNS cord-022526-j9kg00qf 2184 40 . . . cord-022526-j9kg00qf 2185 1 Furthermore furthermore RB cord-022526-j9kg00qf 2185 2 , , , cord-022526-j9kg00qf 2185 3 high high JJ cord-022526-j9kg00qf 2185 4 - - HYPH cord-022526-j9kg00qf 2185 5 molecular molecular JJ cord-022526-j9kg00qf 2185 6 - - HYPH cord-022526-j9kg00qf 2185 7 weight weight NN cord-022526-j9kg00qf 2185 8 polymers polymer NNS cord-022526-j9kg00qf 2185 9 are be VBP cord-022526-j9kg00qf 2185 10 thought think VBN cord-022526-j9kg00qf 2185 11 to to TO cord-022526-j9kg00qf 2185 12 provide provide VB cord-022526-j9kg00qf 2185 13 superior superior JJ cord-022526-j9kg00qf 2185 14 oncotic oncotic JJ cord-022526-j9kg00qf 2185 15 effects effect NNS cord-022526-j9kg00qf 2185 16 in in IN cord-022526-j9kg00qf 2185 17 cases case NNS cord-022526-j9kg00qf 2185 18 of of IN cord-022526-j9kg00qf 2185 19 sepsis sepsis NN cord-022526-j9kg00qf 2185 20 and and CC cord-022526-j9kg00qf 2185 21 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2185 22 , , , cord-022526-j9kg00qf 2185 23 when when WRB cord-022526-j9kg00qf 2185 24 vascular vascular JJ cord-022526-j9kg00qf 2185 25 permeability permeability NN cord-022526-j9kg00qf 2185 26 is be VBZ cord-022526-j9kg00qf 2185 27 increased increase VBN cord-022526-j9kg00qf 2185 28 . . . cord-022526-j9kg00qf 2186 1 Hetastarch Hetastarch NNP cord-022526-j9kg00qf 2186 2 , , , cord-022526-j9kg00qf 2186 3 or or CC cord-022526-j9kg00qf 2186 4 hydroxyethyl hydroxyethyl NN cord-022526-j9kg00qf 2186 5 starch starch NN cord-022526-j9kg00qf 2186 6 , , , cord-022526-j9kg00qf 2186 7 ( ( -LRB- cord-022526-j9kg00qf 2186 8 Hespan Hespan NNP cord-022526-j9kg00qf 2186 9 ) ) -RRB- cord-022526-j9kg00qf 2186 10 is be VBZ cord-022526-j9kg00qf 2186 11 commercially commercially RB cord-022526-j9kg00qf 2186 12 available available JJ cord-022526-j9kg00qf 2186 13 as as IN cord-022526-j9kg00qf 2186 14 a a DT cord-022526-j9kg00qf 2186 15 6 6 CD cord-022526-j9kg00qf 2186 16 % % NN cord-022526-j9kg00qf 2186 17 solution solution NN cord-022526-j9kg00qf 2186 18 in in IN cord-022526-j9kg00qf 2186 19 0.9 0.9 CD cord-022526-j9kg00qf 2186 20 % % NN cord-022526-j9kg00qf 2186 21 sodium sodium NN cord-022526-j9kg00qf 2186 22 chloride chloride NN cord-022526-j9kg00qf 2186 23 . . . cord-022526-j9kg00qf 2187 1 Hetastarch Hetastarch NNP cord-022526-j9kg00qf 2187 2 molecules molecule NNS cord-022526-j9kg00qf 2187 3 have have VBP cord-022526-j9kg00qf 2187 4 very very RB cord-022526-j9kg00qf 2187 5 high high JJ cord-022526-j9kg00qf 2187 6 molecular molecular JJ cord-022526-j9kg00qf 2187 7 weight weight NN cord-022526-j9kg00qf 2187 8 , , , cord-022526-j9kg00qf 2187 9 and and CC cord-022526-j9kg00qf 2187 10 degradation degradation NN cord-022526-j9kg00qf 2187 11 must must MD cord-022526-j9kg00qf 2187 12 occur occur VB cord-022526-j9kg00qf 2187 13 before before IN cord-022526-j9kg00qf 2187 14 renal renal JJ cord-022526-j9kg00qf 2187 15 excretion excretion NN cord-022526-j9kg00qf 2187 16 . . . cord-022526-j9kg00qf 2188 1 191 191 CD cord-022526-j9kg00qf 2189 1 These these DT cord-022526-j9kg00qf 2189 2 properties property NNS cord-022526-j9kg00qf 2189 3 result result VBP cord-022526-j9kg00qf 2189 4 in in IN cord-022526-j9kg00qf 2189 5 a a DT cord-022526-j9kg00qf 2189 6 longer long RBR cord-022526-j9kg00qf 2189 7 plasma plasma NN cord-022526-j9kg00qf 2189 8 half half JJ cord-022526-j9kg00qf 2189 9 - - HYPH cord-022526-j9kg00qf 2189 10 life life NN cord-022526-j9kg00qf 2189 11 and and CC cord-022526-j9kg00qf 2189 12 prolonged prolonged JJ cord-022526-j9kg00qf 2189 13 oncotic oncotic JJ cord-022526-j9kg00qf 2189 14 effects effect NNS cord-022526-j9kg00qf 2189 15 compared compare VBN cord-022526-j9kg00qf 2189 16 with with IN cord-022526-j9kg00qf 2189 17 other other JJ cord-022526-j9kg00qf 2189 18 colloids colloid NNS cord-022526-j9kg00qf 2189 19 ; ; : cord-022526-j9kg00qf 2189 20 persistence persistence NN cord-022526-j9kg00qf 2189 21 of of IN cord-022526-j9kg00qf 2189 22 the the DT cord-022526-j9kg00qf 2189 23 oncotic oncotic JJ cord-022526-j9kg00qf 2189 24 effect effect NN cord-022526-j9kg00qf 2189 25 for for IN cord-022526-j9kg00qf 2189 26 24 24 CD cord-022526-j9kg00qf 2189 27 hours hour NNS cord-022526-j9kg00qf 2189 28 was be VBD cord-022526-j9kg00qf 2189 29 found find VBN cord-022526-j9kg00qf 2189 30 in in IN cord-022526-j9kg00qf 2189 31 hypoproteinemic hypoproteinemic JJ cord-022526-j9kg00qf 2189 32 horses horse NNS cord-022526-j9kg00qf 2189 33 . . . cord-022526-j9kg00qf 2190 1 192 192 CD cord-022526-j9kg00qf 2191 1 A a DT cord-022526-j9kg00qf 2191 2 dosage dosage NN cord-022526-j9kg00qf 2191 3 of of IN cord-022526-j9kg00qf 2191 4 5 5 CD cord-022526-j9kg00qf 2191 5 to to TO cord-022526-j9kg00qf 2191 6 15 15 CD cord-022526-j9kg00qf 2191 7 ml ml NNS cord-022526-j9kg00qf 2191 8 / / SYM cord-022526-j9kg00qf 2191 9 kg kg NNS cord-022526-j9kg00qf 2191 10 given give VBN cord-022526-j9kg00qf 2191 11 by by IN cord-022526-j9kg00qf 2191 12 slow slow JJ cord-022526-j9kg00qf 2191 13 intravenous intravenous JJ cord-022526-j9kg00qf 2191 14 infusion infusion NN cord-022526-j9kg00qf 2191 15 along along IN cord-022526-j9kg00qf 2191 16 with with IN cord-022526-j9kg00qf 2191 17 an an DT cord-022526-j9kg00qf 2191 18 equal equal JJ cord-022526-j9kg00qf 2191 19 or or CC cord-022526-j9kg00qf 2191 20 greater great JJR cord-022526-j9kg00qf 2191 21 volume volume NN cord-022526-j9kg00qf 2191 22 of of IN cord-022526-j9kg00qf 2191 23 crystalloid crystalloid NN cord-022526-j9kg00qf 2191 24 fluids fluid NNS cord-022526-j9kg00qf 2191 25 is be VBZ cord-022526-j9kg00qf 2191 26 recommended recommend VBN cord-022526-j9kg00qf 2191 27 . . . cord-022526-j9kg00qf 2192 1 191 191 CD cord-022526-j9kg00qf 2192 2 , , , cord-022526-j9kg00qf 2192 3 193 193 CD cord-022526-j9kg00qf 2193 1 In in IN cord-022526-j9kg00qf 2193 2 human human JJ cord-022526-j9kg00qf 2193 3 patients patient NNS cord-022526-j9kg00qf 2193 4 , , , cord-022526-j9kg00qf 2193 5 prolonged prolong VBN cord-022526-j9kg00qf 2193 6 activated activate VBN cord-022526-j9kg00qf 2193 7 partial partial JJ cord-022526-j9kg00qf 2193 8 thromboplastin thromboplastin NNP cord-022526-j9kg00qf 2193 9 time time NN cord-022526-j9kg00qf 2193 10 , , , cord-022526-j9kg00qf 2193 11 decreased decrease VBD cord-022526-j9kg00qf 2193 12 factor factor NN cord-022526-j9kg00qf 2193 13 VIII VIII NNP cord-022526-j9kg00qf 2193 14 activity activity NN cord-022526-j9kg00qf 2193 15 , , , cord-022526-j9kg00qf 2193 16 and and CC cord-022526-j9kg00qf 2193 17 decreased decrease VBD cord-022526-j9kg00qf 2193 18 serum serum NN cord-022526-j9kg00qf 2193 19 fibrinogen fibrinogen NN cord-022526-j9kg00qf 2193 20 concentration concentration NN cord-022526-j9kg00qf 2193 21 have have VBP cord-022526-j9kg00qf 2193 22 been be VBN cord-022526-j9kg00qf 2193 23 described describe VBN cord-022526-j9kg00qf 2193 24 in in IN cord-022526-j9kg00qf 2193 25 association association NN cord-022526-j9kg00qf 2193 26 with with IN cord-022526-j9kg00qf 2193 27 hetastarch hetastarch NNP cord-022526-j9kg00qf 2193 28 use use NNP cord-022526-j9kg00qf 2193 29 . . . cord-022526-j9kg00qf 2194 1 194 194 CD cord-022526-j9kg00qf 2195 1 In in IN cord-022526-j9kg00qf 2195 2 the the DT cord-022526-j9kg00qf 2195 3 limited limited JJ cord-022526-j9kg00qf 2195 4 number number NN cord-022526-j9kg00qf 2195 5 of of IN cord-022526-j9kg00qf 2195 6 equine equine JJ cord-022526-j9kg00qf 2195 7 studies study NNS cord-022526-j9kg00qf 2195 8 , , , cord-022526-j9kg00qf 2195 9 bleeding bleed VBG cord-022526-j9kg00qf 2195 10 times time NNS cord-022526-j9kg00qf 2195 11 were be VBD cord-022526-j9kg00qf 2195 12 not not RB cord-022526-j9kg00qf 2195 13 affected affect VBN cord-022526-j9kg00qf 2195 14 195 195 CD cord-022526-j9kg00qf 2195 15 , , , cord-022526-j9kg00qf 2195 16 196 196 CD cord-022526-j9kg00qf 2195 17 ; ; : cord-022526-j9kg00qf 2195 18 however however RB cord-022526-j9kg00qf 2195 19 , , , cord-022526-j9kg00qf 2195 20 one one PRP cord-022526-j9kg00qf 2195 21 should should MD cord-022526-j9kg00qf 2195 22 monitor monitor VB cord-022526-j9kg00qf 2195 23 patients patient NNS cord-022526-j9kg00qf 2195 24 treated treat VBN cord-022526-j9kg00qf 2195 25 with with IN cord-022526-j9kg00qf 2195 26 hetastarch hetastarch NNP cord-022526-j9kg00qf 2195 27 for for IN cord-022526-j9kg00qf 2195 28 coagulopathy coagulopathy NN cord-022526-j9kg00qf 2195 29 . . . cord-022526-j9kg00qf 2196 1 One one PRP cord-022526-j9kg00qf 2196 2 should should MD cord-022526-j9kg00qf 2196 3 base base VB cord-022526-j9kg00qf 2196 4 correction correction NN cord-022526-j9kg00qf 2196 5 of of IN cord-022526-j9kg00qf 2196 6 serum serum NN cord-022526-j9kg00qf 2196 7 electrolyte electrolyte NN cord-022526-j9kg00qf 2196 8 concentrations concentration NNS cord-022526-j9kg00qf 2196 9 on on IN cord-022526-j9kg00qf 2196 10 the the DT cord-022526-j9kg00qf 2196 11 results result NNS cord-022526-j9kg00qf 2196 12 of of IN cord-022526-j9kg00qf 2196 13 laboratory laboratory NN cord-022526-j9kg00qf 2196 14 evaluation evaluation NN cord-022526-j9kg00qf 2196 15 . . . cord-022526-j9kg00qf 2197 1 Ideally ideally RB cord-022526-j9kg00qf 2197 2 , , , cord-022526-j9kg00qf 2197 3 one one PRP cord-022526-j9kg00qf 2197 4 should should MD cord-022526-j9kg00qf 2197 5 evaluate evaluate VB cord-022526-j9kg00qf 2197 6 serum serum NN cord-022526-j9kg00qf 2197 7 electrolyte electrolyte JJ cord-022526-j9kg00qf 2197 8 concentrations concentration NNS cord-022526-j9kg00qf 2197 9 of of IN cord-022526-j9kg00qf 2197 10 patients patient NNS cord-022526-j9kg00qf 2197 11 receiving receive VBG cord-022526-j9kg00qf 2197 12 fluid fluid JJ cord-022526-j9kg00qf 2197 13 therapy therapy NN cord-022526-j9kg00qf 2197 14 daily daily RB cord-022526-j9kg00qf 2197 15 . . . cord-022526-j9kg00qf 2198 1 One one PRP cord-022526-j9kg00qf 2198 2 should should MD cord-022526-j9kg00qf 2198 3 take take VB cord-022526-j9kg00qf 2198 4 ongoing ongoing JJ cord-022526-j9kg00qf 2198 5 losses loss NNS cord-022526-j9kg00qf 2198 6 and and CC cord-022526-j9kg00qf 2198 7 lack lack NN cord-022526-j9kg00qf 2198 8 of of IN cord-022526-j9kg00qf 2198 9 dietary dietary JJ cord-022526-j9kg00qf 2198 10 intake intake NN cord-022526-j9kg00qf 2198 11 into into IN cord-022526-j9kg00qf 2198 12 account account NN cord-022526-j9kg00qf 2198 13 , , , cord-022526-j9kg00qf 2198 14 especially especially RB cord-022526-j9kg00qf 2198 15 when when WRB cord-022526-j9kg00qf 2198 16 serum serum NN cord-022526-j9kg00qf 2198 17 concentrations concentration NNS cord-022526-j9kg00qf 2198 18 , , , cord-022526-j9kg00qf 2198 19 as as IN cord-022526-j9kg00qf 2198 20 in in IN cord-022526-j9kg00qf 2198 21 the the DT cord-022526-j9kg00qf 2198 22 case case NN cord-022526-j9kg00qf 2198 23 of of IN cord-022526-j9kg00qf 2198 24 potassium potassium NN cord-022526-j9kg00qf 2198 25 , , , cord-022526-j9kg00qf 2198 26 poorly poorly RB cord-022526-j9kg00qf 2198 27 reflect reflect VBP cord-022526-j9kg00qf 2198 28 total total JJ cord-022526-j9kg00qf 2198 29 body body NN cord-022526-j9kg00qf 2198 30 electrolyte electrolyte NN cord-022526-j9kg00qf 2198 31 stores store NNS cord-022526-j9kg00qf 2198 32 . . . cord-022526-j9kg00qf 2199 1 Potassium potassium NN cord-022526-j9kg00qf 2199 2 supplementation supplementation NN cord-022526-j9kg00qf 2199 3 is be VBZ cord-022526-j9kg00qf 2199 4 recommended recommend VBN cord-022526-j9kg00qf 2199 5 in in IN cord-022526-j9kg00qf 2199 6 patients patient NNS cord-022526-j9kg00qf 2199 7 experiencing experience VBG cord-022526-j9kg00qf 2199 8 prolonged prolong VBN cord-022526-j9kg00qf 2199 9 ( ( -LRB- cord-022526-j9kg00qf 2199 10 greater great JJR cord-022526-j9kg00qf 2199 11 than than IN cord-022526-j9kg00qf 2199 12 48 48 CD cord-022526-j9kg00qf 2199 13 hours hour NNS cord-022526-j9kg00qf 2199 14 ) ) -RRB- cord-022526-j9kg00qf 2199 15 periods period NNS cord-022526-j9kg00qf 2199 16 of of IN cord-022526-j9kg00qf 2199 17 anorexia anorexia NN cord-022526-j9kg00qf 2199 18 . . . cord-022526-j9kg00qf 2200 1 One one PRP cord-022526-j9kg00qf 2200 2 can can MD cord-022526-j9kg00qf 2200 3 add add VB cord-022526-j9kg00qf 2200 4 calcium calcium NN cord-022526-j9kg00qf 2200 5 in in IN cord-022526-j9kg00qf 2200 6 the the DT cord-022526-j9kg00qf 2200 7 form form NN cord-022526-j9kg00qf 2200 8 of of IN cord-022526-j9kg00qf 2200 9 calcium calcium NN cord-022526-j9kg00qf 2200 10 gluconate gluconate NN cord-022526-j9kg00qf 2200 11 , , , cord-022526-j9kg00qf 2200 12 which which WDT cord-022526-j9kg00qf 2200 13 is be VBZ cord-022526-j9kg00qf 2200 14 available available JJ cord-022526-j9kg00qf 2200 15 as as IN cord-022526-j9kg00qf 2200 16 a a DT cord-022526-j9kg00qf 2200 17 23 23 CD cord-022526-j9kg00qf 2200 18 % % NN cord-022526-j9kg00qf 2200 19 solution solution NN cord-022526-j9kg00qf 2200 20 . . . cord-022526-j9kg00qf 2201 1 Based base VBN cord-022526-j9kg00qf 2201 2 on on IN cord-022526-j9kg00qf 2201 3 a a DT cord-022526-j9kg00qf 2201 4 study study NN cord-022526-j9kg00qf 2201 5 in in IN cord-022526-j9kg00qf 2201 6 healthy healthy JJ cord-022526-j9kg00qf 2201 7 horses horse NNS cord-022526-j9kg00qf 2201 8 , , , cord-022526-j9kg00qf 2201 9 rates rate NNS cord-022526-j9kg00qf 2201 10 of of IN cord-022526-j9kg00qf 2201 11 administration administration NN cord-022526-j9kg00qf 2201 12 for for IN cord-022526-j9kg00qf 2201 13 calcium calcium NN cord-022526-j9kg00qf 2201 14 gluconate gluconate NN cord-022526-j9kg00qf 2201 15 in in IN cord-022526-j9kg00qf 2201 16 the the DT cord-022526-j9kg00qf 2201 17 range range NN cord-022526-j9kg00qf 2201 18 of of IN cord-022526-j9kg00qf 2201 19 0.1 0.1 CD cord-022526-j9kg00qf 2201 20 to to TO cord-022526-j9kg00qf 2201 21 0.4 0.4 CD cord-022526-j9kg00qf 2201 22 mg mg NNS cord-022526-j9kg00qf 2201 23 / / SYM cord-022526-j9kg00qf 2201 24 kg kg NNP cord-022526-j9kg00qf 2201 25 / / SYM cord-022526-j9kg00qf 2201 26 min min NNP cord-022526-j9kg00qf 2201 27 are be VBP cord-022526-j9kg00qf 2201 28 recommended recommend VBN cord-022526-j9kg00qf 2201 29 , , , cord-022526-j9kg00qf 2201 30 197 197 CD cord-022526-j9kg00qf 2201 31 and and CC cord-022526-j9kg00qf 2201 32 as as IN cord-022526-j9kg00qf 2201 33 a a DT cord-022526-j9kg00qf 2201 34 guideline guideline NN cord-022526-j9kg00qf 2201 35 , , , cord-022526-j9kg00qf 2201 36 one one PRP cord-022526-j9kg00qf 2201 37 should should MD cord-022526-j9kg00qf 2201 38 administer administer VB cord-022526-j9kg00qf 2201 39 0.5 0.5 CD cord-022526-j9kg00qf 2201 40 to to TO cord-022526-j9kg00qf 2201 41 1 1 CD cord-022526-j9kg00qf 2201 42 ml ml NNS cord-022526-j9kg00qf 2201 43 / / SYM cord-022526-j9kg00qf 2201 44 kg kg NN cord-022526-j9kg00qf 2201 45 body body NN cord-022526-j9kg00qf 2201 46 mass mass NN cord-022526-j9kg00qf 2201 47 per per IN cord-022526-j9kg00qf 2201 48 day day NN cord-022526-j9kg00qf 2201 49 of of IN cord-022526-j9kg00qf 2201 50 a a DT cord-022526-j9kg00qf 2201 51 23 23 CD cord-022526-j9kg00qf 2201 52 % % NN cord-022526-j9kg00qf 2201 53 solution solution NN cord-022526-j9kg00qf 2201 54 . . . cord-022526-j9kg00qf 2202 1 One one PRP cord-022526-j9kg00qf 2202 2 can can MD cord-022526-j9kg00qf 2202 3 add add VB cord-022526-j9kg00qf 2202 4 potassium potassium NN cord-022526-j9kg00qf 2202 5 in in IN cord-022526-j9kg00qf 2202 6 the the DT cord-022526-j9kg00qf 2202 7 form form NN cord-022526-j9kg00qf 2202 8 of of IN cord-022526-j9kg00qf 2202 9 potassium potassium NN cord-022526-j9kg00qf 2202 10 chloride chloride NN cord-022526-j9kg00qf 2202 11 or or CC cord-022526-j9kg00qf 2202 12 potassium potassium NN cord-022526-j9kg00qf 2202 13 gluconate gluconate NN cord-022526-j9kg00qf 2202 14 to to IN cord-022526-j9kg00qf 2202 15 intravenous intravenous JJ cord-022526-j9kg00qf 2202 16 solutions solution NNS cord-022526-j9kg00qf 2202 17 at at IN cord-022526-j9kg00qf 2202 18 a a DT cord-022526-j9kg00qf 2202 19 dose dose NN cord-022526-j9kg00qf 2202 20 of of IN cord-022526-j9kg00qf 2202 21 20 20 CD cord-022526-j9kg00qf 2202 22 to to TO cord-022526-j9kg00qf 2202 23 40 40 CD cord-022526-j9kg00qf 2202 24 mEq mEq NNS cord-022526-j9kg00qf 2202 25 / / SYM cord-022526-j9kg00qf 2202 26 L L NNP cord-022526-j9kg00qf 2202 27 given give VBN cord-022526-j9kg00qf 2202 28 at at IN cord-022526-j9kg00qf 2202 29 a a DT cord-022526-j9kg00qf 2202 30 maintenance maintenance NN cord-022526-j9kg00qf 2202 31 rate rate NN cord-022526-j9kg00qf 2202 32 . . . cord-022526-j9kg00qf 2203 1 Administration administration NN cord-022526-j9kg00qf 2203 2 of of IN cord-022526-j9kg00qf 2203 3 potassium potassium NN cord-022526-j9kg00qf 2203 4 should should MD cord-022526-j9kg00qf 2203 5 not not RB cord-022526-j9kg00qf 2203 6 exceed exceed VB cord-022526-j9kg00qf 2203 7 a a DT cord-022526-j9kg00qf 2203 8 rate rate NN cord-022526-j9kg00qf 2203 9 of of IN cord-022526-j9kg00qf 2203 10 0.5 0.5 CD cord-022526-j9kg00qf 2203 11 to to TO cord-022526-j9kg00qf 2203 12 1 1 CD cord-022526-j9kg00qf 2203 13 mEq mEq NNS cord-022526-j9kg00qf 2203 14 / / SYM cord-022526-j9kg00qf 2203 15 kg kg NNP cord-022526-j9kg00qf 2203 16 / / SYM cord-022526-j9kg00qf 2203 17 hr hr NN cord-022526-j9kg00qf 2203 18 . . . cord-022526-j9kg00qf 2204 1 Metabolic metabolic JJ cord-022526-j9kg00qf 2204 2 acidosis acidosis NN cord-022526-j9kg00qf 2204 3 in in IN cord-022526-j9kg00qf 2204 4 endotoxic endotoxic JJ cord-022526-j9kg00qf 2204 5 shock shock NN cord-022526-j9kg00qf 2204 6 is be VBZ cord-022526-j9kg00qf 2204 7 attributable attributable JJ cord-022526-j9kg00qf 2204 8 to to IN cord-022526-j9kg00qf 2204 9 lactic lactic VB cord-022526-j9kg00qf 2204 10 acidemia acidemia NN cord-022526-j9kg00qf 2204 11 and and CC cord-022526-j9kg00qf 2204 12 inadequate inadequate JJ cord-022526-j9kg00qf 2204 13 tissue tissue NN cord-022526-j9kg00qf 2204 14 perfusion perfusion NN cord-022526-j9kg00qf 2204 15 . . . cord-022526-j9kg00qf 2205 1 198 198 CD cord-022526-j9kg00qf 2205 2 Acid acid NN cord-022526-j9kg00qf 2205 3 - - HYPH cord-022526-j9kg00qf 2205 4 base base NN cord-022526-j9kg00qf 2205 5 balance balance NN cord-022526-j9kg00qf 2205 6 often often RB cord-022526-j9kg00qf 2205 7 improves improve VBZ cord-022526-j9kg00qf 2205 8 considerably considerably RB cord-022526-j9kg00qf 2205 9 after after IN cord-022526-j9kg00qf 2205 10 fluid fluid JJ cord-022526-j9kg00qf 2205 11 resuscitation resuscitation NN cord-022526-j9kg00qf 2205 12 ( ( -LRB- cord-022526-j9kg00qf 2205 13 preferably preferably RB cord-022526-j9kg00qf 2205 14 with with IN cord-022526-j9kg00qf 2205 15 alkalinizing alkalinizing NN cord-022526-j9kg00qf 2205 16 solutions solution NNS cord-022526-j9kg00qf 2205 17 such such JJ cord-022526-j9kg00qf 2205 18 as as IN cord-022526-j9kg00qf 2205 19 lactated lactate VBN cord-022526-j9kg00qf 2205 20 Ringer Ringer NNP cord-022526-j9kg00qf 2205 21 's 's POS cord-022526-j9kg00qf 2205 22 solution solution NN cord-022526-j9kg00qf 2205 23 ) ) -RRB- cord-022526-j9kg00qf 2205 24 alone alone RB cord-022526-j9kg00qf 2205 25 ; ; : cord-022526-j9kg00qf 2205 26 however however RB cord-022526-j9kg00qf 2205 27 , , , cord-022526-j9kg00qf 2205 28 additional additional JJ cord-022526-j9kg00qf 2205 29 sodium sodium NN cord-022526-j9kg00qf 2205 30 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2205 31 may may MD cord-022526-j9kg00qf 2205 32 be be VB cord-022526-j9kg00qf 2205 33 required require VBN cord-022526-j9kg00qf 2205 34 in in IN cord-022526-j9kg00qf 2205 35 cases case NNS cord-022526-j9kg00qf 2205 36 in in IN cord-022526-j9kg00qf 2205 37 which which WDT cord-022526-j9kg00qf 2205 38 serum serum NN cord-022526-j9kg00qf 2205 39 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2205 40 concentration concentration NN cord-022526-j9kg00qf 2205 41 remains remain VBZ cord-022526-j9kg00qf 2205 42 below below IN cord-022526-j9kg00qf 2205 43 15 15 CD cord-022526-j9kg00qf 2205 44 mEq mEq NNS cord-022526-j9kg00qf 2205 45 / / SYM cord-022526-j9kg00qf 2205 46 L. L. NNP cord-022526-j9kg00qf 2206 1 For for IN cord-022526-j9kg00qf 2206 2 adult adult NN cord-022526-j9kg00qf 2206 3 horses horse NNS cord-022526-j9kg00qf 2206 4 , , , cord-022526-j9kg00qf 2206 5 the the DT cord-022526-j9kg00qf 2206 6 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2206 7 deficit deficit NN cord-022526-j9kg00qf 2206 8 ( ( -LRB- cord-022526-j9kg00qf 2206 9 in in IN cord-022526-j9kg00qf 2206 10 mEq mEq NNS cord-022526-j9kg00qf 2206 11 HCO HCO NNP cord-022526-j9kg00qf 2206 12 3 3 CD cord-022526-j9kg00qf 2206 13 ) ) -RRB- cord-022526-j9kg00qf 2206 14 is be VBZ cord-022526-j9kg00qf 2206 15 calculated calculate VBN cord-022526-j9kg00qf 2206 16 as as IN cord-022526-j9kg00qf 2206 17 0.3 0.3 CD cord-022526-j9kg00qf 2206 18 × × NN cord-022526-j9kg00qf 2206 19 body body NN cord-022526-j9kg00qf 2206 20 mass mass NN cord-022526-j9kg00qf 2206 21 ( ( -LRB- cord-022526-j9kg00qf 2206 22 kg kg NNP cord-022526-j9kg00qf 2206 23 ) ) -RRB- cord-022526-j9kg00qf 2206 24 × × NN cord-022526-j9kg00qf 2206 25 base base NN cord-022526-j9kg00qf 2206 26 deficit deficit NN cord-022526-j9kg00qf 2206 27 , , , cord-022526-j9kg00qf 2206 28 whereas whereas IN cord-022526-j9kg00qf 2206 29 for for IN cord-022526-j9kg00qf 2206 30 foals foal NNS cord-022526-j9kg00qf 2206 31 one one PRP cord-022526-j9kg00qf 2206 32 should should MD cord-022526-j9kg00qf 2206 33 use use VB cord-022526-j9kg00qf 2206 34 a a DT cord-022526-j9kg00qf 2206 35 factor factor NN cord-022526-j9kg00qf 2206 36 of of IN cord-022526-j9kg00qf 2206 37 0.5 0.5 CD cord-022526-j9kg00qf 2206 38 . . . cord-022526-j9kg00qf 2207 1 As as IN cord-022526-j9kg00qf 2207 2 a a DT cord-022526-j9kg00qf 2207 3 general general JJ cord-022526-j9kg00qf 2207 4 rule rule NN cord-022526-j9kg00qf 2207 5 , , , cord-022526-j9kg00qf 2207 6 one one PRP cord-022526-j9kg00qf 2207 7 should should MD cord-022526-j9kg00qf 2207 8 administer administer VB cord-022526-j9kg00qf 2207 9 half half PDT cord-022526-j9kg00qf 2207 10 the the DT cord-022526-j9kg00qf 2207 11 required require VBN cord-022526-j9kg00qf 2207 12 amount amount NN cord-022526-j9kg00qf 2207 13 as as IN cord-022526-j9kg00qf 2207 14 a a DT cord-022526-j9kg00qf 2207 15 bolus bolus NN cord-022526-j9kg00qf 2207 16 followed follow VBN cord-022526-j9kg00qf 2207 17 by by IN cord-022526-j9kg00qf 2207 18 the the DT cord-022526-j9kg00qf 2207 19 remaining remain VBG cord-022526-j9kg00qf 2207 20 half half NN cord-022526-j9kg00qf 2207 21 over over IN cord-022526-j9kg00qf 2207 22 12 12 CD cord-022526-j9kg00qf 2207 23 to to TO cord-022526-j9kg00qf 2207 24 24 24 CD cord-022526-j9kg00qf 2207 25 hours hour NNS cord-022526-j9kg00qf 2207 26 . . . cord-022526-j9kg00qf 2208 1 Because because IN cord-022526-j9kg00qf 2208 2 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2208 3 is be VBZ cord-022526-j9kg00qf 2208 4 a a DT cord-022526-j9kg00qf 2208 5 dynamic dynamic JJ cord-022526-j9kg00qf 2208 6 process process NN cord-022526-j9kg00qf 2208 7 and and CC cord-022526-j9kg00qf 2208 8 losses loss NNS cord-022526-j9kg00qf 2208 9 are be VBP cord-022526-j9kg00qf 2208 10 ongoing ongoing JJ cord-022526-j9kg00qf 2208 11 , , , cord-022526-j9kg00qf 2208 12 one one PRP cord-022526-j9kg00qf 2208 13 should should MD cord-022526-j9kg00qf 2208 14 reevaluate reevaluate VB cord-022526-j9kg00qf 2208 15 acid acid NN cord-022526-j9kg00qf 2208 16 - - HYPH cord-022526-j9kg00qf 2208 17 base base NN cord-022526-j9kg00qf 2208 18 status status NN cord-022526-j9kg00qf 2208 19 at at IN cord-022526-j9kg00qf 2208 20 least least JJS cord-022526-j9kg00qf 2208 21 once once RB cord-022526-j9kg00qf 2208 22 daily daily RB cord-022526-j9kg00qf 2208 23 . . . cord-022526-j9kg00qf 2209 1 Foals foal NNS cord-022526-j9kg00qf 2209 2 with with IN cord-022526-j9kg00qf 2209 3 sepsis sepsis NN cord-022526-j9kg00qf 2209 4 are be VBP cord-022526-j9kg00qf 2209 5 frequently frequently RB cord-022526-j9kg00qf 2209 6 hypoglycemic hypoglycemic JJ cord-022526-j9kg00qf 2209 7 , , , cord-022526-j9kg00qf 2209 8 and and CC cord-022526-j9kg00qf 2209 9 5 5 CD cord-022526-j9kg00qf 2209 10 % % NN cord-022526-j9kg00qf 2209 11 dextrose dextrose NN cord-022526-j9kg00qf 2209 12 solutions solution NNS cord-022526-j9kg00qf 2209 13 are be VBP cord-022526-j9kg00qf 2209 14 useful useful JJ cord-022526-j9kg00qf 2209 15 as as IN cord-022526-j9kg00qf 2209 16 initial initial JJ cord-022526-j9kg00qf 2209 17 resuscitation resuscitation NN cord-022526-j9kg00qf 2209 18 fluids fluid NNS cord-022526-j9kg00qf 2209 19 . . . cord-022526-j9kg00qf 2210 1 One one PRP cord-022526-j9kg00qf 2210 2 should should MD cord-022526-j9kg00qf 2210 3 reduce reduce VB cord-022526-j9kg00qf 2210 4 the the DT cord-022526-j9kg00qf 2210 5 glucose glucose NN cord-022526-j9kg00qf 2210 6 concentration concentration NN cord-022526-j9kg00qf 2210 7 of of IN cord-022526-j9kg00qf 2210 8 intravenous intravenous JJ cord-022526-j9kg00qf 2210 9 solutions solution NNS cord-022526-j9kg00qf 2210 10 according accord VBG cord-022526-j9kg00qf 2210 11 to to IN cord-022526-j9kg00qf 2210 12 the the DT cord-022526-j9kg00qf 2210 13 blood blood NN cord-022526-j9kg00qf 2210 14 glucose glucose NN cord-022526-j9kg00qf 2210 15 concentration concentration NN cord-022526-j9kg00qf 2210 16 to to TO cord-022526-j9kg00qf 2210 17 avoid avoid VB cord-022526-j9kg00qf 2210 18 prolonged prolonged JJ cord-022526-j9kg00qf 2210 19 hyperglycemia hyperglycemia NN cord-022526-j9kg00qf 2210 20 . . . cord-022526-j9kg00qf 2211 1 Administration Administration NNP cord-022526-j9kg00qf 2211 2 of of IN cord-022526-j9kg00qf 2211 3 hyperimmune hyperimmune NNP cord-022526-j9kg00qf 2211 4 plasma plasma NNP cord-022526-j9kg00qf 2211 5 ( ( -LRB- cord-022526-j9kg00qf 2211 6 20 20 CD cord-022526-j9kg00qf 2211 7 to to TO cord-022526-j9kg00qf 2211 8 40 40 CD cord-022526-j9kg00qf 2211 9 ml ml NNS cord-022526-j9kg00qf 2211 10 / / SYM cord-022526-j9kg00qf 2211 11 kg kg NN cord-022526-j9kg00qf 2211 12 body body NN cord-022526-j9kg00qf 2211 13 mass mass NN cord-022526-j9kg00qf 2211 14 ) ) -RRB- cord-022526-j9kg00qf 2211 15 is be VBZ cord-022526-j9kg00qf 2211 16 highly highly RB cord-022526-j9kg00qf 2211 17 recommended recommend VBN cord-022526-j9kg00qf 2211 18 in in IN cord-022526-j9kg00qf 2211 19 foals foal NNS cord-022526-j9kg00qf 2211 20 with with IN cord-022526-j9kg00qf 2211 21 evidence evidence NN cord-022526-j9kg00qf 2211 22 of of IN cord-022526-j9kg00qf 2211 23 partial partial JJ cord-022526-j9kg00qf 2211 24 or or CC cord-022526-j9kg00qf 2211 25 complete complete JJ cord-022526-j9kg00qf 2211 26 failure failure NN cord-022526-j9kg00qf 2211 27 of of IN cord-022526-j9kg00qf 2211 28 passive passive JJ cord-022526-j9kg00qf 2211 29 transfer transfer NN cord-022526-j9kg00qf 2211 30 . . . cord-022526-j9kg00qf 2212 1 One one PRP cord-022526-j9kg00qf 2212 2 should should MD cord-022526-j9kg00qf 2212 3 consider consider VB cord-022526-j9kg00qf 2212 4 positive positive JJ cord-022526-j9kg00qf 2212 5 inotropic inotropic NNP cord-022526-j9kg00qf 2212 6 and and CC cord-022526-j9kg00qf 2212 7 vasomotor vasomotor NNP cord-022526-j9kg00qf 2212 8 agents agent NNS cord-022526-j9kg00qf 2212 9 in in IN cord-022526-j9kg00qf 2212 10 patients patient NNS cord-022526-j9kg00qf 2212 11 with with IN cord-022526-j9kg00qf 2212 12 persistently persistently RB cord-022526-j9kg00qf 2212 13 inadequate inadequate JJ cord-022526-j9kg00qf 2212 14 tissue tissue NN cord-022526-j9kg00qf 2212 15 perfusion perfusion NN cord-022526-j9kg00qf 2212 16 . . . cord-022526-j9kg00qf 2213 1 Lower low JJR cord-022526-j9kg00qf 2213 2 dosages dosage NNS cord-022526-j9kg00qf 2213 3 of of IN cord-022526-j9kg00qf 2213 4 dopamine dopamine NN cord-022526-j9kg00qf 2213 5 ( ( -LRB- cord-022526-j9kg00qf 2213 6 0.5 0.5 CD cord-022526-j9kg00qf 2213 7 to to TO cord-022526-j9kg00qf 2213 8 2 2 CD cord-022526-j9kg00qf 2213 9 µg µg NN cord-022526-j9kg00qf 2213 10 / / SYM cord-022526-j9kg00qf 2213 11 kg kg NN cord-022526-j9kg00qf 2213 12 / / SYM cord-022526-j9kg00qf 2213 13 min min NN cord-022526-j9kg00qf 2213 14 ) ) -RRB- cord-022526-j9kg00qf 2213 15 result result VBP cord-022526-j9kg00qf 2213 16 in in IN cord-022526-j9kg00qf 2213 17 vasodilation vasodilation NN cord-022526-j9kg00qf 2213 18 of of IN cord-022526-j9kg00qf 2213 19 the the DT cord-022526-j9kg00qf 2213 20 renal renal JJ cord-022526-j9kg00qf 2213 21 , , , cord-022526-j9kg00qf 2213 22 mesenteric mesenteric JJ cord-022526-j9kg00qf 2213 23 , , , cord-022526-j9kg00qf 2213 24 coronary coronary JJ cord-022526-j9kg00qf 2213 25 , , , cord-022526-j9kg00qf 2213 26 and and CC cord-022526-j9kg00qf 2213 27 intracerebral intracerebral JJ cord-022526-j9kg00qf 2213 28 vasculature vasculature NN cord-022526-j9kg00qf 2213 29 via via IN cord-022526-j9kg00qf 2213 30 dopaminergic dopaminergic JJ cord-022526-j9kg00qf 2213 31 effects effect NNS cord-022526-j9kg00qf 2213 32 , , , cord-022526-j9kg00qf 2213 33 whereas whereas IN cord-022526-j9kg00qf 2213 34 higher high JJR cord-022526-j9kg00qf 2213 35 dosages dosage NNS cord-022526-j9kg00qf 2213 36 ( ( -LRB- cord-022526-j9kg00qf 2213 37 up up IN cord-022526-j9kg00qf 2213 38 to to TO cord-022526-j9kg00qf 2213 39 10 10 CD cord-022526-j9kg00qf 2213 40 µg µg NN cord-022526-j9kg00qf 2213 41 / / SYM cord-022526-j9kg00qf 2213 42 kg kg NNP cord-022526-j9kg00qf 2213 43 / / SYM cord-022526-j9kg00qf 2213 44 min min NN cord-022526-j9kg00qf 2213 45 ) ) -RRB- cord-022526-j9kg00qf 2213 46 also also RB cord-022526-j9kg00qf 2213 47 exert exert VBP cord-022526-j9kg00qf 2213 48 stimulation stimulation NN cord-022526-j9kg00qf 2213 49 of of IN cord-022526-j9kg00qf 2213 50 β β NN cord-022526-j9kg00qf 2213 51 1 1 CD cord-022526-j9kg00qf 2213 52 -adrenergic -adrenergic JJ cord-022526-j9kg00qf 2213 53 receptors receptor NNS cord-022526-j9kg00qf 2213 54 , , , cord-022526-j9kg00qf 2213 55 resulting result VBG cord-022526-j9kg00qf 2213 56 in in IN cord-022526-j9kg00qf 2213 57 increased increase VBN cord-022526-j9kg00qf 2213 58 myocardial myocardial JJ cord-022526-j9kg00qf 2213 59 contractility contractility NN cord-022526-j9kg00qf 2213 60 and and CC cord-022526-j9kg00qf 2213 61 heart heart NN cord-022526-j9kg00qf 2213 62 rate rate NN cord-022526-j9kg00qf 2213 63 . . . cord-022526-j9kg00qf 2214 1 199 199 CD cord-022526-j9kg00qf 2214 2 Dobutamine Dobutamine NNP cord-022526-j9kg00qf 2214 3 is be VBZ cord-022526-j9kg00qf 2214 4 a a DT cord-022526-j9kg00qf 2214 5 direct direct JJ cord-022526-j9kg00qf 2214 6 β β NN cord-022526-j9kg00qf 2214 7 1 1 CD cord-022526-j9kg00qf 2214 8 -adrenergic -adrenergic JJ cord-022526-j9kg00qf 2214 9 agonist agonist NN cord-022526-j9kg00qf 2214 10 and and CC cord-022526-j9kg00qf 2214 11 does do VBZ cord-022526-j9kg00qf 2214 12 not not RB cord-022526-j9kg00qf 2214 13 appear appear VB cord-022526-j9kg00qf 2214 14 to to TO cord-022526-j9kg00qf 2214 15 have have VB cord-022526-j9kg00qf 2214 16 significant significant JJ cord-022526-j9kg00qf 2214 17 vasodilator vasodilator NN cord-022526-j9kg00qf 2214 18 properties property NNS cord-022526-j9kg00qf 2214 19 . . . cord-022526-j9kg00qf 2215 1 Dosages dosage NNS cord-022526-j9kg00qf 2215 2 for for IN cord-022526-j9kg00qf 2215 3 dobutamine dobutamine NN cord-022526-j9kg00qf 2215 4 of of IN cord-022526-j9kg00qf 2215 5 1 1 CD cord-022526-j9kg00qf 2215 6 to to IN cord-022526-j9kg00qf 2215 7 5 5 CD cord-022526-j9kg00qf 2215 8 µg µg NN cord-022526-j9kg00qf 2215 9 / / SYM cord-022526-j9kg00qf 2215 10 kg kg NNP cord-022526-j9kg00qf 2215 11 / / SYM cord-022526-j9kg00qf 2215 12 min min NN cord-022526-j9kg00qf 2215 13 as as IN cord-022526-j9kg00qf 2215 14 continuous continuous JJ cord-022526-j9kg00qf 2215 15 intravenous intravenous JJ cord-022526-j9kg00qf 2215 16 infusion infusion NN cord-022526-j9kg00qf 2215 17 have have VBP cord-022526-j9kg00qf 2215 18 been be VBN cord-022526-j9kg00qf 2215 19 recommended recommend VBN cord-022526-j9kg00qf 2215 20 for for IN cord-022526-j9kg00qf 2215 21 use use NN cord-022526-j9kg00qf 2215 22 in in IN cord-022526-j9kg00qf 2215 23 horses horse NNS cord-022526-j9kg00qf 2215 24 . . . cord-022526-j9kg00qf 2216 1 In in IN cord-022526-j9kg00qf 2216 2 addition addition NN cord-022526-j9kg00qf 2216 3 , , , cord-022526-j9kg00qf 2216 4 norepinephrine norepinephrine NN cord-022526-j9kg00qf 2216 5 was be VBD cord-022526-j9kg00qf 2216 6 evaluated evaluate VBN cord-022526-j9kg00qf 2216 7 in in IN cord-022526-j9kg00qf 2216 8 hypotensive hypotensive JJ cord-022526-j9kg00qf 2216 9 critically critically RB cord-022526-j9kg00qf 2216 10 ill ill JJ cord-022526-j9kg00qf 2216 11 foals foal NNS cord-022526-j9kg00qf 2216 12 that that WDT cord-022526-j9kg00qf 2216 13 were be VBD cord-022526-j9kg00qf 2216 14 refractory refractory JJ cord-022526-j9kg00qf 2216 15 to to IN cord-022526-j9kg00qf 2216 16 the the DT cord-022526-j9kg00qf 2216 17 effects effect NNS cord-022526-j9kg00qf 2216 18 of of IN cord-022526-j9kg00qf 2216 19 dopamine dopamine NN cord-022526-j9kg00qf 2216 20 and and CC cord-022526-j9kg00qf 2216 21 dobutamine dobutamine NN cord-022526-j9kg00qf 2216 22 . . . cord-022526-j9kg00qf 2217 1 200 200 CD cord-022526-j9kg00qf 2218 1 At at IN cord-022526-j9kg00qf 2218 2 dosages dosage NNS cord-022526-j9kg00qf 2218 3 up up IN cord-022526-j9kg00qf 2218 4 to to TO cord-022526-j9kg00qf 2218 5 1.5 1.5 CD cord-022526-j9kg00qf 2218 6 µg µg NN cord-022526-j9kg00qf 2218 7 / / SYM cord-022526-j9kg00qf 2218 8 kg kg NNP cord-022526-j9kg00qf 2218 9 / / SYM cord-022526-j9kg00qf 2218 10 min min NNP cord-022526-j9kg00qf 2218 11 administered administer VBN cord-022526-j9kg00qf 2218 12 concurrently concurrently RB cord-022526-j9kg00qf 2218 13 with with IN cord-022526-j9kg00qf 2218 14 dobutamine dobutamine NN cord-022526-j9kg00qf 2218 15 , , , cord-022526-j9kg00qf 2218 16 six six CD cord-022526-j9kg00qf 2218 17 out out IN cord-022526-j9kg00qf 2218 18 of of IN cord-022526-j9kg00qf 2218 19 seven seven CD cord-022526-j9kg00qf 2218 20 foals foal NNS cord-022526-j9kg00qf 2218 21 showed show VBD cord-022526-j9kg00qf 2218 22 an an DT cord-022526-j9kg00qf 2218 23 increase increase NN cord-022526-j9kg00qf 2218 24 in in IN cord-022526-j9kg00qf 2218 25 mean mean JJ cord-022526-j9kg00qf 2218 26 arterial arterial JJ cord-022526-j9kg00qf 2218 27 pressure pressure NN cord-022526-j9kg00qf 2218 28 , , , cord-022526-j9kg00qf 2218 29 and and CC cord-022526-j9kg00qf 2218 30 all all DT cord-022526-j9kg00qf 2218 31 foals foal NNS cord-022526-j9kg00qf 2218 32 had have VBD cord-022526-j9kg00qf 2218 33 increased increase VBN cord-022526-j9kg00qf 2218 34 urine urine NN cord-022526-j9kg00qf 2218 35 output output NN cord-022526-j9kg00qf 2218 36 . . . cord-022526-j9kg00qf 2219 1 Because because IN cord-022526-j9kg00qf 2219 2 of of IN cord-022526-j9kg00qf 2219 3 the the DT cord-022526-j9kg00qf 2219 4 risk risk NN cord-022526-j9kg00qf 2219 5 of of IN cord-022526-j9kg00qf 2219 6 cardiac cardiac JJ cord-022526-j9kg00qf 2219 7 side side NN cord-022526-j9kg00qf 2219 8 effects effect NNS cord-022526-j9kg00qf 2219 9 , , , cord-022526-j9kg00qf 2219 10 close close JJ cord-022526-j9kg00qf 2219 11 monitoring monitoring NN cord-022526-j9kg00qf 2219 12 of of IN cord-022526-j9kg00qf 2219 13 heart heart NN cord-022526-j9kg00qf 2219 14 rate rate NN cord-022526-j9kg00qf 2219 15 and and CC cord-022526-j9kg00qf 2219 16 rhythm rhythm NN cord-022526-j9kg00qf 2219 17 should should MD cord-022526-j9kg00qf 2219 18 accompany accompany VB cord-022526-j9kg00qf 2219 19 infusion infusion NN cord-022526-j9kg00qf 2219 20 of of IN cord-022526-j9kg00qf 2219 21 inotropes inotrope NNS cord-022526-j9kg00qf 2219 22 . . . cord-022526-j9kg00qf 2220 1 Indirect indirect JJ cord-022526-j9kg00qf 2220 2 blood blood NN cord-022526-j9kg00qf 2220 3 pressure pressure NN cord-022526-j9kg00qf 2220 4 measurements measurement NNS cord-022526-j9kg00qf 2220 5 using use VBG cord-022526-j9kg00qf 2220 6 a a DT cord-022526-j9kg00qf 2220 7 tail tail NN cord-022526-j9kg00qf 2220 8 cuff cuff NN cord-022526-j9kg00qf 2220 9 may may MD cord-022526-j9kg00qf 2220 10 be be VB cord-022526-j9kg00qf 2220 11 used use VBN cord-022526-j9kg00qf 2220 12 to to TO cord-022526-j9kg00qf 2220 13 monitor monitor VB cord-022526-j9kg00qf 2220 14 the the DT cord-022526-j9kg00qf 2220 15 effects effect NNS cord-022526-j9kg00qf 2220 16 of of IN cord-022526-j9kg00qf 2220 17 treatment treatment NN cord-022526-j9kg00qf 2220 18 . . . cord-022526-j9kg00qf 2221 1 More more RBR cord-022526-j9kg00qf 2221 2 frequently frequently RB cord-022526-j9kg00qf 2221 3 than than IN cord-022526-j9kg00qf 2221 4 overt overt JJ cord-022526-j9kg00qf 2221 5 thrombosis thrombosis NN cord-022526-j9kg00qf 2221 6 or or CC cord-022526-j9kg00qf 2221 7 bleeding bleed VBG cord-022526-j9kg00qf 2221 8 attributable attributable JJ cord-022526-j9kg00qf 2221 9 to to IN cord-022526-j9kg00qf 2221 10 DIC DIC NNP cord-022526-j9kg00qf 2221 11 , , , cord-022526-j9kg00qf 2221 12 hemostatic hemostatic JJ cord-022526-j9kg00qf 2221 13 abnormalities abnormality NNS cord-022526-j9kg00qf 2221 14 occur occur VBP cord-022526-j9kg00qf 2221 15 in in IN cord-022526-j9kg00qf 2221 16 the the DT cord-022526-j9kg00qf 2221 17 form form NN cord-022526-j9kg00qf 2221 18 of of IN cord-022526-j9kg00qf 2221 19 alterations alteration NNS cord-022526-j9kg00qf 2221 20 in in IN cord-022526-j9kg00qf 2221 21 the the DT cord-022526-j9kg00qf 2221 22 coagulation coagulation NN cord-022526-j9kg00qf 2221 23 profile profile NN cord-022526-j9kg00qf 2221 24 . . . cord-022526-j9kg00qf 2222 1 A a DT cord-022526-j9kg00qf 2222 2 procoagulant procoagulant JJ cord-022526-j9kg00qf 2222 3 state state NN cord-022526-j9kg00qf 2222 4 with with IN cord-022526-j9kg00qf 2222 5 shortened shorten VBN cord-022526-j9kg00qf 2222 6 bleeding bleed VBG cord-022526-j9kg00qf 2222 7 times time NNS cord-022526-j9kg00qf 2222 8 or or CC cord-022526-j9kg00qf 2222 9 prolonged prolong VBN cord-022526-j9kg00qf 2222 10 bleeding bleeding NN cord-022526-j9kg00qf 2222 11 times time NNS cord-022526-j9kg00qf 2222 12 caused cause VBN cord-022526-j9kg00qf 2222 13 by by IN cord-022526-j9kg00qf 2222 14 consumption consumption NN cord-022526-j9kg00qf 2222 15 of of IN cord-022526-j9kg00qf 2222 16 clotting clotting NN cord-022526-j9kg00qf 2222 17 factors factor NNS cord-022526-j9kg00qf 2222 18 may may MD cord-022526-j9kg00qf 2222 19 be be VB cord-022526-j9kg00qf 2222 20 evident evident JJ cord-022526-j9kg00qf 2222 21 . . . cord-022526-j9kg00qf 2223 1 One one PRP cord-022526-j9kg00qf 2223 2 should should MD cord-022526-j9kg00qf 2223 3 address address VB cord-022526-j9kg00qf 2223 4 abnormalities abnormality NNS cord-022526-j9kg00qf 2223 5 in in IN cord-022526-j9kg00qf 2223 6 the the DT cord-022526-j9kg00qf 2223 7 coagulation coagulation NN cord-022526-j9kg00qf 2223 8 profile profile NN cord-022526-j9kg00qf 2223 9 as as RB cord-022526-j9kg00qf 2223 10 early early RB cord-022526-j9kg00qf 2223 11 as as IN cord-022526-j9kg00qf 2223 12 possible possible JJ cord-022526-j9kg00qf 2223 13 but but CC cord-022526-j9kg00qf 2223 14 especially especially RB cord-022526-j9kg00qf 2223 15 if if IN cord-022526-j9kg00qf 2223 16 they -PRON- PRP cord-022526-j9kg00qf 2223 17 persist persist VBP cord-022526-j9kg00qf 2223 18 more more JJR cord-022526-j9kg00qf 2223 19 than than IN cord-022526-j9kg00qf 2223 20 24 24 CD cord-022526-j9kg00qf 2223 21 hours hour NNS cord-022526-j9kg00qf 2223 22 after after IN cord-022526-j9kg00qf 2223 23 initiation initiation NN cord-022526-j9kg00qf 2223 24 of of IN cord-022526-j9kg00qf 2223 25 therapy therapy NN cord-022526-j9kg00qf 2223 26 . . . cord-022526-j9kg00qf 2224 1 Because because IN cord-022526-j9kg00qf 2224 2 of of IN cord-022526-j9kg00qf 2224 3 the the DT cord-022526-j9kg00qf 2224 4 complex complex JJ cord-022526-j9kg00qf 2224 5 interactions interaction NNS cord-022526-j9kg00qf 2224 6 of of IN cord-022526-j9kg00qf 2224 7 coagulation coagulation NN cord-022526-j9kg00qf 2224 8 and and CC cord-022526-j9kg00qf 2224 9 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 2224 10 during during IN cord-022526-j9kg00qf 2224 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2224 12 , , , cord-022526-j9kg00qf 2224 13 one one PRP cord-022526-j9kg00qf 2224 14 should should MD cord-022526-j9kg00qf 2224 15 combine combine VB cord-022526-j9kg00qf 2224 16 anticoagulant anticoagulant JJ cord-022526-j9kg00qf 2224 17 therapy therapy NN cord-022526-j9kg00qf 2224 18 with with IN cord-022526-j9kg00qf 2224 19 the the DT cord-022526-j9kg00qf 2224 20 administration administration NN cord-022526-j9kg00qf 2224 21 of of IN cord-022526-j9kg00qf 2224 22 fresh fresh JJ cord-022526-j9kg00qf 2224 23 frozen frozen JJ cord-022526-j9kg00qf 2224 24 plasma plasma NN cord-022526-j9kg00qf 2224 25 to to TO cord-022526-j9kg00qf 2224 26 replace replace VB cord-022526-j9kg00qf 2224 27 clotting clotting NN cord-022526-j9kg00qf 2224 28 and and CC cord-022526-j9kg00qf 2224 29 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 2224 30 factors factor NNS cord-022526-j9kg00qf 2224 31 . . . cord-022526-j9kg00qf 2225 1 Heparin heparin NN cord-022526-j9kg00qf 2225 2 acts act VBZ cord-022526-j9kg00qf 2225 3 as as IN cord-022526-j9kg00qf 2225 4 an an DT cord-022526-j9kg00qf 2225 5 anticoagulant anticoagulant NN cord-022526-j9kg00qf 2225 6 by by IN cord-022526-j9kg00qf 2225 7 activation activation NN cord-022526-j9kg00qf 2225 8 of of IN cord-022526-j9kg00qf 2225 9 AT AT NNP cord-022526-j9kg00qf 2225 10 III iii CD cord-022526-j9kg00qf 2225 11 and and CC cord-022526-j9kg00qf 2225 12 subsequent subsequent JJ cord-022526-j9kg00qf 2225 13 inhibition inhibition NN cord-022526-j9kg00qf 2225 14 of of IN cord-022526-j9kg00qf 2225 15 thrombin thrombin NN cord-022526-j9kg00qf 2225 16 , , , cord-022526-j9kg00qf 2225 17 release release NN cord-022526-j9kg00qf 2225 18 of of IN cord-022526-j9kg00qf 2225 19 tissue tissue NN cord-022526-j9kg00qf 2225 20 factor factor NN cord-022526-j9kg00qf 2225 21 pathway pathway NN cord-022526-j9kg00qf 2225 22 inhibitor inhibitor NN cord-022526-j9kg00qf 2225 23 from from IN cord-022526-j9kg00qf 2225 24 endothelial endothelial JJ cord-022526-j9kg00qf 2225 25 cells cell NNS cord-022526-j9kg00qf 2225 26 , , , cord-022526-j9kg00qf 2225 27 and and CC cord-022526-j9kg00qf 2225 28 inhibition inhibition NN cord-022526-j9kg00qf 2225 29 of of IN cord-022526-j9kg00qf 2225 30 platelet platelet NN cord-022526-j9kg00qf 2225 31 aggregation aggregation NN cord-022526-j9kg00qf 2225 32 . . . cord-022526-j9kg00qf 2226 1 201 201 CD cord-022526-j9kg00qf 2227 1 Because because IN cord-022526-j9kg00qf 2227 2 endogenous endogenous JJ cord-022526-j9kg00qf 2227 3 AT at IN cord-022526-j9kg00qf 2227 4 III iii CD cord-022526-j9kg00qf 2227 5 levels level NNS cord-022526-j9kg00qf 2227 6 frequently frequently RB cord-022526-j9kg00qf 2227 7 are be VBP cord-022526-j9kg00qf 2227 8 decreased decrease VBN cord-022526-j9kg00qf 2227 9 in in IN cord-022526-j9kg00qf 2227 10 patients patient NNS cord-022526-j9kg00qf 2227 11 with with IN cord-022526-j9kg00qf 2227 12 coagulopathy coagulopathy NN cord-022526-j9kg00qf 2227 13 , , , cord-022526-j9kg00qf 2227 14 addition addition NN cord-022526-j9kg00qf 2227 15 of of IN cord-022526-j9kg00qf 2227 16 heparin heparin NN cord-022526-j9kg00qf 2227 17 to to IN cord-022526-j9kg00qf 2227 18 fresh fresh JJ cord-022526-j9kg00qf 2227 19 frozen frozen JJ cord-022526-j9kg00qf 2227 20 plasma plasma NN cord-022526-j9kg00qf 2227 21 may may MD cord-022526-j9kg00qf 2227 22 be be VB cord-022526-j9kg00qf 2227 23 the the DT cord-022526-j9kg00qf 2227 24 most most RBS cord-022526-j9kg00qf 2227 25 effective effective JJ cord-022526-j9kg00qf 2227 26 route route NN cord-022526-j9kg00qf 2227 27 of of IN cord-022526-j9kg00qf 2227 28 administration administration NN cord-022526-j9kg00qf 2227 29 . . . cord-022526-j9kg00qf 2228 1 An an DT cord-022526-j9kg00qf 2228 2 initial initial JJ cord-022526-j9kg00qf 2228 3 dose dose NN cord-022526-j9kg00qf 2228 4 of of IN cord-022526-j9kg00qf 2228 5 100 100 CD cord-022526-j9kg00qf 2228 6 IU IU NNP cord-022526-j9kg00qf 2228 7 / / SYM cord-022526-j9kg00qf 2228 8 kg kg NN cord-022526-j9kg00qf 2228 9 body body NN cord-022526-j9kg00qf 2228 10 mass mass NN cord-022526-j9kg00qf 2228 11 followed follow VBN cord-022526-j9kg00qf 2228 12 by by IN cord-022526-j9kg00qf 2228 13 40 40 CD cord-022526-j9kg00qf 2228 14 to to TO cord-022526-j9kg00qf 2228 15 80 80 CD cord-022526-j9kg00qf 2228 16 IU IU NNP cord-022526-j9kg00qf 2228 17 / / SYM cord-022526-j9kg00qf 2228 18 kg kg NN cord-022526-j9kg00qf 2228 19 body body NN cord-022526-j9kg00qf 2228 20 mass mass NN cord-022526-j9kg00qf 2228 21 3 3 CD cord-022526-j9kg00qf 2228 22 times times NNP cord-022526-j9kg00qf 2228 23 daily daily RB cord-022526-j9kg00qf 2228 24 has have VBZ cord-022526-j9kg00qf 2228 25 been be VBN cord-022526-j9kg00qf 2228 26 recommended recommend VBN cord-022526-j9kg00qf 2228 27 . . . cord-022526-j9kg00qf 2229 1 121 121 CD cord-022526-j9kg00qf 2229 2 Anemia anemia NN cord-022526-j9kg00qf 2229 3 caused cause VBN cord-022526-j9kg00qf 2229 4 by by IN cord-022526-j9kg00qf 2229 5 erythrocyte erythrocyte NN cord-022526-j9kg00qf 2229 6 agglutination agglutination NN cord-022526-j9kg00qf 2229 7 occurs occur VBZ cord-022526-j9kg00qf 2229 8 in in IN cord-022526-j9kg00qf 2229 9 some some DT cord-022526-j9kg00qf 2229 10 patients patient NNS cord-022526-j9kg00qf 2229 11 during during IN cord-022526-j9kg00qf 2229 12 therapy therapy NN cord-022526-j9kg00qf 2229 13 with with IN cord-022526-j9kg00qf 2229 14 unfractionated unfractionated JJ cord-022526-j9kg00qf 2229 15 heparin heparin NNP cord-022526-j9kg00qf 2229 16 202,203 202,203 CD cord-022526-j9kg00qf 2229 17 but but CC cord-022526-j9kg00qf 2229 18 typically typically RB cord-022526-j9kg00qf 2229 19 resolves resolve VBZ cord-022526-j9kg00qf 2229 20 within within IN cord-022526-j9kg00qf 2229 21 96 96 CD cord-022526-j9kg00qf 2229 22 hours hour NNS cord-022526-j9kg00qf 2229 23 if if IN cord-022526-j9kg00qf 2229 24 therapy therapy NN cord-022526-j9kg00qf 2229 25 is be VBZ cord-022526-j9kg00qf 2229 26 discontinued discontinue VBN cord-022526-j9kg00qf 2229 27 . . . cord-022526-j9kg00qf 2230 1 121 121 CD cord-022526-j9kg00qf 2231 1 Because because IN cord-022526-j9kg00qf 2231 2 of of IN cord-022526-j9kg00qf 2231 3 the the DT cord-022526-j9kg00qf 2231 4 risk risk NN cord-022526-j9kg00qf 2231 5 of of IN cord-022526-j9kg00qf 2231 6 microthrombosis microthrombosis NN cord-022526-j9kg00qf 2231 7 associated associate VBN cord-022526-j9kg00qf 2231 8 with with IN cord-022526-j9kg00qf 2231 9 erythrocyte erythrocyte NN cord-022526-j9kg00qf 2231 10 agglutination agglutination NN cord-022526-j9kg00qf 2231 11 , , , cord-022526-j9kg00qf 2231 12 use use NN cord-022526-j9kg00qf 2231 13 of of IN cord-022526-j9kg00qf 2231 14 low low JJ cord-022526-j9kg00qf 2231 15 - - HYPH cord-022526-j9kg00qf 2231 16 molecular molecular JJ cord-022526-j9kg00qf 2231 17 - - HYPH cord-022526-j9kg00qf 2231 18 weight weight NN cord-022526-j9kg00qf 2231 19 heparin heparin NN cord-022526-j9kg00qf 2231 20 ( ( -LRB- cord-022526-j9kg00qf 2231 21 50 50 CD cord-022526-j9kg00qf 2231 22 IU IU NNP cord-022526-j9kg00qf 2231 23 / / SYM cord-022526-j9kg00qf 2231 24 kg kg NN cord-022526-j9kg00qf 2231 25 body body NN cord-022526-j9kg00qf 2231 26 mass mass NN cord-022526-j9kg00qf 2231 27 subcutaneously subcutaneously RB cord-022526-j9kg00qf 2231 28 every every DT cord-022526-j9kg00qf 2231 29 24 24 CD cord-022526-j9kg00qf 2231 30 hours hour NNS cord-022526-j9kg00qf 2231 31 ) ) -RRB- cord-022526-j9kg00qf 2231 32 has have VBZ cord-022526-j9kg00qf 2231 33 been be VBN cord-022526-j9kg00qf 2231 34 recommended recommend VBN cord-022526-j9kg00qf 2231 35 204 204 CD cord-022526-j9kg00qf 2231 36 but but CC cord-022526-j9kg00qf 2231 37 may may MD cord-022526-j9kg00qf 2231 38 be be VB cord-022526-j9kg00qf 2231 39 cost cost NN cord-022526-j9kg00qf 2231 40 - - HYPH cord-022526-j9kg00qf 2231 41 prohibitive prohibitive JJ cord-022526-j9kg00qf 2231 42 . . . cord-022526-j9kg00qf 2232 1 One one CD cord-022526-j9kg00qf 2232 2 may may MD cord-022526-j9kg00qf 2232 3 give give VB cord-022526-j9kg00qf 2232 4 aspirin aspirin NN cord-022526-j9kg00qf 2232 5 orally orally RB cord-022526-j9kg00qf 2232 6 ( ( -LRB- cord-022526-j9kg00qf 2232 7 10 10 CD cord-022526-j9kg00qf 2232 8 to to TO cord-022526-j9kg00qf 2232 9 20 20 CD cord-022526-j9kg00qf 2232 10 mg mg NN cord-022526-j9kg00qf 2232 11 / / SYM cord-022526-j9kg00qf 2232 12 kg kg NNP cord-022526-j9kg00qf 2232 13 body body NN cord-022526-j9kg00qf 2232 14 mass mass NN cord-022526-j9kg00qf 2232 15 , , , cord-022526-j9kg00qf 2232 16 every every DT cord-022526-j9kg00qf 2232 17 48 48 CD cord-022526-j9kg00qf 2232 18 hours hour NNS cord-022526-j9kg00qf 2232 19 ) ) -RRB- cord-022526-j9kg00qf 2232 20 , , , cord-022526-j9kg00qf 2232 21 which which WDT cord-022526-j9kg00qf 2232 22 irreversibly irreversibly RB cord-022526-j9kg00qf 2232 23 inhibits inhibit VBZ cord-022526-j9kg00qf 2232 24 platelet platelet NN cord-022526-j9kg00qf 2232 25 COX COX NNP cord-022526-j9kg00qf 2232 26 activity activity NN cord-022526-j9kg00qf 2232 27 , , , cord-022526-j9kg00qf 2232 28 to to TO cord-022526-j9kg00qf 2232 29 inhibit inhibit VB cord-022526-j9kg00qf 2232 30 platelet platelet NN cord-022526-j9kg00qf 2232 31 aggregation aggregation NN cord-022526-j9kg00qf 2232 32 and and CC cord-022526-j9kg00qf 2232 33 microthrombosis microthrombosis NN cord-022526-j9kg00qf 2232 34 . . . cord-022526-j9kg00qf 2233 1 Platelet platelet NN cord-022526-j9kg00qf 2233 2 hyperaggregability hyperaggregability NN cord-022526-j9kg00qf 2233 3 has have VBZ cord-022526-j9kg00qf 2233 4 been be VBN cord-022526-j9kg00qf 2233 5 implicated implicate VBN cord-022526-j9kg00qf 2233 6 in in IN cord-022526-j9kg00qf 2233 7 the the DT cord-022526-j9kg00qf 2233 8 pathogenesis pathogenesis NN cord-022526-j9kg00qf 2233 9 of of IN cord-022526-j9kg00qf 2233 10 carbohydrate carbohydrate NN cord-022526-j9kg00qf 2233 11 - - HYPH cord-022526-j9kg00qf 2233 12 induced induce VBN cord-022526-j9kg00qf 2233 13 laminitis laminitis NN cord-022526-j9kg00qf 2233 14 , , , cord-022526-j9kg00qf 2233 15 205 205 CD cord-022526-j9kg00qf 2233 16 and and CC cord-022526-j9kg00qf 2233 17 heparin heparin NN cord-022526-j9kg00qf 2233 18 and and CC cord-022526-j9kg00qf 2233 19 aspirin aspirin NN cord-022526-j9kg00qf 2233 20 have have VBP cord-022526-j9kg00qf 2233 21 been be VBN cord-022526-j9kg00qf 2233 22 recommended recommend VBN cord-022526-j9kg00qf 2233 23 to to TO cord-022526-j9kg00qf 2233 24 prevent prevent VB cord-022526-j9kg00qf 2233 25 development development NN cord-022526-j9kg00qf 2233 26 of of IN cord-022526-j9kg00qf 2233 27 laminitis laminitis NN cord-022526-j9kg00qf 2233 28 . . . cord-022526-j9kg00qf 2234 1 In in IN cord-022526-j9kg00qf 2234 2 an an DT cord-022526-j9kg00qf 2234 3 in in FW cord-022526-j9kg00qf 2234 4 vitro vitro FW cord-022526-j9kg00qf 2234 5 study study NN cord-022526-j9kg00qf 2234 6 , , , cord-022526-j9kg00qf 2234 7 however however RB cord-022526-j9kg00qf 2234 8 , , , cord-022526-j9kg00qf 2234 9 aspirin aspirin NN cord-022526-j9kg00qf 2234 10 did do VBD cord-022526-j9kg00qf 2234 11 not not RB cord-022526-j9kg00qf 2234 12 inhibit inhibit VB cord-022526-j9kg00qf 2234 13 endotoxin endotoxin NN cord-022526-j9kg00qf 2234 14 - - HYPH cord-022526-j9kg00qf 2234 15 induced induce VBN cord-022526-j9kg00qf 2234 16 platelet platelet NN cord-022526-j9kg00qf 2234 17 aggregation aggregation NN cord-022526-j9kg00qf 2234 18 . . . cord-022526-j9kg00qf 2235 1 206 206 CD cord-022526-j9kg00qf 2235 2 Luteolysis Luteolysis NNP cord-022526-j9kg00qf 2235 3 caused cause VBN cord-022526-j9kg00qf 2235 4 by by IN cord-022526-j9kg00qf 2235 5 increased increase VBN cord-022526-j9kg00qf 2235 6 concentrations concentration NNS cord-022526-j9kg00qf 2235 7 of of IN cord-022526-j9kg00qf 2235 8 PGF PGF NNP cord-022526-j9kg00qf 2235 9 2α 2α CD cord-022526-j9kg00qf 2235 10 leads lead VBZ cord-022526-j9kg00qf 2235 11 to to IN cord-022526-j9kg00qf 2235 12 pregnancy pregnancy NN cord-022526-j9kg00qf 2235 13 loss loss NN cord-022526-j9kg00qf 2235 14 in in IN cord-022526-j9kg00qf 2235 15 endotoxemic endotoxemic NNP cord-022526-j9kg00qf 2235 16 mares mare NNS cord-022526-j9kg00qf 2235 17 before before IN cord-022526-j9kg00qf 2235 18 day day NN cord-022526-j9kg00qf 2235 19 55 55 CD cord-022526-j9kg00qf 2235 20 of of IN cord-022526-j9kg00qf 2235 21 pregnancy pregnancy NN cord-022526-j9kg00qf 2235 22 . . . cord-022526-j9kg00qf 2236 1 207 207 CD cord-022526-j9kg00qf 2237 1 Daily Daily NNP cord-022526-j9kg00qf 2237 2 administration administration NN cord-022526-j9kg00qf 2237 3 of of IN cord-022526-j9kg00qf 2237 4 altrenogest altrenogest NNP cord-022526-j9kg00qf 2238 1 ( ( -LRB- cord-022526-j9kg00qf 2238 2 Regu Regu NNP cord-022526-j9kg00qf 2238 3 - - HYPH cord-022526-j9kg00qf 2238 4 Mate Mate NNP cord-022526-j9kg00qf 2238 5 , , , cord-022526-j9kg00qf 2238 6 Hoechst Hoechst NNP cord-022526-j9kg00qf 2238 7 - - HYPH cord-022526-j9kg00qf 2238 8 Roussel Roussel NNP cord-022526-j9kg00qf 2238 9 Agri Agri NNP cord-022526-j9kg00qf 2238 10 - - HYPH cord-022526-j9kg00qf 2238 11 Vet Vet NNP cord-022526-j9kg00qf 2238 12 , , , cord-022526-j9kg00qf 2238 13 Somerville Somerville NNP cord-022526-j9kg00qf 2238 14 , , , cord-022526-j9kg00qf 2238 15 New New NNP cord-022526-j9kg00qf 2238 16 Jersey Jersey NNP cord-022526-j9kg00qf 2238 17 ) ) -RRB- cord-022526-j9kg00qf 2238 18 at at IN cord-022526-j9kg00qf 2238 19 a a DT cord-022526-j9kg00qf 2238 20 dose dose NN cord-022526-j9kg00qf 2238 21 of of IN cord-022526-j9kg00qf 2238 22 44 44 CD cord-022526-j9kg00qf 2238 23 mg mg NNS cord-022526-j9kg00qf 2238 24 orally orally RB cord-022526-j9kg00qf 2238 25 consistently consistently RB cord-022526-j9kg00qf 2238 26 prevented prevent VBD cord-022526-j9kg00qf 2238 27 fetal fetal JJ cord-022526-j9kg00qf 2238 28 loss loss NN cord-022526-j9kg00qf 2238 29 in in IN cord-022526-j9kg00qf 2238 30 mares mare NNS cord-022526-j9kg00qf 2238 31 if if IN cord-022526-j9kg00qf 2238 32 administered administer VBN cord-022526-j9kg00qf 2238 33 until until IN cord-022526-j9kg00qf 2238 34 day day NN cord-022526-j9kg00qf 2238 35 70 70 CD cord-022526-j9kg00qf 2238 36 of of IN cord-022526-j9kg00qf 2238 37 pregnancy pregnancy NN cord-022526-j9kg00qf 2238 38 . . . cord-022526-j9kg00qf 2239 1 100 100 CD cord-022526-j9kg00qf 2239 2 Treatment treatment NN cord-022526-j9kg00qf 2239 3 with with IN cord-022526-j9kg00qf 2239 4 flunixin flunixin NNP cord-022526-j9kg00qf 2239 5 meglumine meglumine NNP cord-022526-j9kg00qf 2239 6 , , , cord-022526-j9kg00qf 2239 7 by by IN cord-022526-j9kg00qf 2239 8 blockade blockade NN cord-022526-j9kg00qf 2239 9 of of IN cord-022526-j9kg00qf 2239 10 PGF PGF NNP cord-022526-j9kg00qf 2239 11 2α 2α CD cord-022526-j9kg00qf 2239 12 release release NN cord-022526-j9kg00qf 2239 13 , , , cord-022526-j9kg00qf 2239 14 101 101 CD cord-022526-j9kg00qf 2239 15 also also RB cord-022526-j9kg00qf 2239 16 may may MD cord-022526-j9kg00qf 2239 17 contribute contribute VB cord-022526-j9kg00qf 2239 18 to to IN cord-022526-j9kg00qf 2239 19 the the DT cord-022526-j9kg00qf 2239 20 maintenance maintenance NN cord-022526-j9kg00qf 2239 21 of of IN cord-022526-j9kg00qf 2239 22 pregnancy pregnancy NN cord-022526-j9kg00qf 2239 23 in in IN cord-022526-j9kg00qf 2239 24 endotoxemic endotoxemic NNP cord-022526-j9kg00qf 2239 25 mares mare NNS cord-022526-j9kg00qf 2239 26 . . . cord-022526-j9kg00qf 2240 1 The the DT cord-022526-j9kg00qf 2240 2 pathogenesis pathogenesis NN cord-022526-j9kg00qf 2240 3 of of IN cord-022526-j9kg00qf 2240 4 fetal fetal JJ cord-022526-j9kg00qf 2240 5 loss loss NN cord-022526-j9kg00qf 2240 6 and and CC cord-022526-j9kg00qf 2240 7 abortion abortion NN cord-022526-j9kg00qf 2240 8 caused cause VBN cord-022526-j9kg00qf 2240 9 by by IN cord-022526-j9kg00qf 2240 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2240 11 , , , cord-022526-j9kg00qf 2240 12 surgery surgery NN cord-022526-j9kg00qf 2240 13 , , , cord-022526-j9kg00qf 2240 14 or or CC cord-022526-j9kg00qf 2240 15 systemic systemic JJ cord-022526-j9kg00qf 2240 16 disease disease NN cord-022526-j9kg00qf 2240 17 later later RB cord-022526-j9kg00qf 2240 18 in in IN cord-022526-j9kg00qf 2240 19 gestation gestation NN cord-022526-j9kg00qf 2240 20 is be VBZ cord-022526-j9kg00qf 2240 21 not not RB cord-022526-j9kg00qf 2240 22 understood understand VBN cord-022526-j9kg00qf 2240 23 completely completely RB cord-022526-j9kg00qf 2240 24 . . . cord-022526-j9kg00qf 2241 1 Proposed propose VBN cord-022526-j9kg00qf 2241 2 mechanisms mechanism NNS cord-022526-j9kg00qf 2241 3 include include VBP cord-022526-j9kg00qf 2241 4 direct direct JJ cord-022526-j9kg00qf 2241 5 effects effect NNS cord-022526-j9kg00qf 2241 6 on on IN cord-022526-j9kg00qf 2241 7 the the DT cord-022526-j9kg00qf 2241 8 fetus fetus NN cord-022526-j9kg00qf 2241 9 , , , cord-022526-j9kg00qf 2241 10 placental placental JJ cord-022526-j9kg00qf 2241 11 function function NN cord-022526-j9kg00qf 2241 12 , , , cord-022526-j9kg00qf 2241 13 or or CC cord-022526-j9kg00qf 2241 14 placental placental JJ cord-022526-j9kg00qf 2241 15 progesterone progesterone NN cord-022526-j9kg00qf 2241 16 production production NN cord-022526-j9kg00qf 2241 17 . . . cord-022526-j9kg00qf 2242 1 208 208 CD cord-022526-j9kg00qf 2243 1 The the DT cord-022526-j9kg00qf 2243 2 pathophysiology pathophysiology NN cord-022526-j9kg00qf 2243 3 of of IN cord-022526-j9kg00qf 2243 4 laminitis laminitis NN cord-022526-j9kg00qf 2243 5 caused cause VBN cord-022526-j9kg00qf 2243 6 by by IN cord-022526-j9kg00qf 2243 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2243 8 is be VBZ cord-022526-j9kg00qf 2243 9 understood understand VBN cord-022526-j9kg00qf 2243 10 incompletely incompletely RB cord-022526-j9kg00qf 2243 11 ; ; : cord-022526-j9kg00qf 2243 12 however however RB cord-022526-j9kg00qf 2243 13 , , , cord-022526-j9kg00qf 2243 14 decreased decrease VBD cord-022526-j9kg00qf 2243 15 digital digital JJ cord-022526-j9kg00qf 2243 16 blood blood NN cord-022526-j9kg00qf 2243 17 flow flow NN cord-022526-j9kg00qf 2244 1 209 209 CD cord-022526-j9kg00qf 2244 2 , , , cord-022526-j9kg00qf 2244 3 210 210 CD cord-022526-j9kg00qf 2244 4 and and CC cord-022526-j9kg00qf 2244 5 intravascular intravascular JJ cord-022526-j9kg00qf 2244 6 microthrombosis microthrombosis NN cord-022526-j9kg00qf 2244 7 have have VBP cord-022526-j9kg00qf 2244 8 been be VBN cord-022526-j9kg00qf 2244 9 implicated implicate VBN cord-022526-j9kg00qf 2244 10 . . . cord-022526-j9kg00qf 2245 1 Decreased decrease VBN cord-022526-j9kg00qf 2245 2 NO no DT cord-022526-j9kg00qf 2245 3 production production NN cord-022526-j9kg00qf 2245 4 by by IN cord-022526-j9kg00qf 2245 5 vascular vascular JJ cord-022526-j9kg00qf 2245 6 endothelial endothelial JJ cord-022526-j9kg00qf 2245 7 cells cell NNS cord-022526-j9kg00qf 2245 8 in in IN cord-022526-j9kg00qf 2245 9 response response NN cord-022526-j9kg00qf 2245 10 to to IN cord-022526-j9kg00qf 2245 11 endotoxin endotoxin NN cord-022526-j9kg00qf 2245 12 has have VBZ cord-022526-j9kg00qf 2245 13 been be VBN cord-022526-j9kg00qf 2245 14 suggested suggest VBN cord-022526-j9kg00qf 2245 15 as as IN cord-022526-j9kg00qf 2245 16 a a DT cord-022526-j9kg00qf 2245 17 mechanism mechanism NN cord-022526-j9kg00qf 2245 18 for for IN cord-022526-j9kg00qf 2245 19 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 2245 20 and and CC cord-022526-j9kg00qf 2245 21 decreased decrease VBD cord-022526-j9kg00qf 2245 22 blood blood NN cord-022526-j9kg00qf 2245 23 flow flow NN cord-022526-j9kg00qf 2245 24 211 211 CD cord-022526-j9kg00qf 2245 25 ; ; : cord-022526-j9kg00qf 2245 26 however however RB cord-022526-j9kg00qf 2245 27 , , , cord-022526-j9kg00qf 2245 28 use use NN cord-022526-j9kg00qf 2245 29 of of IN cord-022526-j9kg00qf 2245 30 NO no DT cord-022526-j9kg00qf 2245 31 donors donor NNS cord-022526-j9kg00qf 2245 32 remains remain VBZ cord-022526-j9kg00qf 2245 33 controversial controversial JJ cord-022526-j9kg00qf 2245 34 . . . cord-022526-j9kg00qf 2246 1 Maintenance maintenance NN cord-022526-j9kg00qf 2246 2 of of IN cord-022526-j9kg00qf 2246 3 adequate adequate JJ cord-022526-j9kg00qf 2246 4 peripheral peripheral JJ cord-022526-j9kg00qf 2246 5 perfusion perfusion NN cord-022526-j9kg00qf 2246 6 and and CC cord-022526-j9kg00qf 2246 7 anticoagulant anticoagulant JJ cord-022526-j9kg00qf 2246 8 and and CC cord-022526-j9kg00qf 2246 9 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2246 10 therapy therapy NN cord-022526-j9kg00qf 2246 11 may may MD cord-022526-j9kg00qf 2246 12 be be VB cord-022526-j9kg00qf 2246 13 helpful helpful JJ cord-022526-j9kg00qf 2246 14 in in IN cord-022526-j9kg00qf 2246 15 preventing prevent VBG cord-022526-j9kg00qf 2246 16 and and CC cord-022526-j9kg00qf 2246 17 treating treat VBG cord-022526-j9kg00qf 2246 18 laminitis laminitis NN cord-022526-j9kg00qf 2246 19 caused cause VBN cord-022526-j9kg00qf 2246 20 by by IN cord-022526-j9kg00qf 2246 21 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2246 22 . . . cord-022526-j9kg00qf 2247 1 Although although IN cord-022526-j9kg00qf 2247 2 the the DT cord-022526-j9kg00qf 2247 3 innate innate JJ cord-022526-j9kg00qf 2247 4 immune immune JJ cord-022526-j9kg00qf 2247 5 response response NN cord-022526-j9kg00qf 2247 6 to to IN cord-022526-j9kg00qf 2247 7 endotoxin endotoxin NN cord-022526-j9kg00qf 2247 8 ( ( -LRB- cord-022526-j9kg00qf 2247 9 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 2247 10 ) ) -RRB- cord-022526-j9kg00qf 2247 11 is be VBZ cord-022526-j9kg00qf 2247 12 crucially crucially RB cord-022526-j9kg00qf 2247 13 important important JJ cord-022526-j9kg00qf 2247 14 for for IN cord-022526-j9kg00qf 2247 15 the the DT cord-022526-j9kg00qf 2247 16 preservation preservation NN cord-022526-j9kg00qf 2247 17 of of IN cord-022526-j9kg00qf 2247 18 homeostasis homeostasis NN cord-022526-j9kg00qf 2247 19 and and CC cord-022526-j9kg00qf 2247 20 health health NN cord-022526-j9kg00qf 2247 21 , , , cord-022526-j9kg00qf 2247 22 large large JJ cord-022526-j9kg00qf 2247 23 amounts amount NNS cord-022526-j9kg00qf 2247 24 of of IN cord-022526-j9kg00qf 2247 25 endotoxin endotoxin NN cord-022526-j9kg00qf 2247 26 can can MD cord-022526-j9kg00qf 2247 27 evoke evoke VB cord-022526-j9kg00qf 2247 28 an an DT cord-022526-j9kg00qf 2247 29 excessive excessive JJ cord-022526-j9kg00qf 2247 30 and and CC cord-022526-j9kg00qf 2247 31 uncontrolled uncontrolled JJ cord-022526-j9kg00qf 2247 32 inflammatory inflammatory JJ cord-022526-j9kg00qf 2247 33 response response NN cord-022526-j9kg00qf 2247 34 and and CC cord-022526-j9kg00qf 2247 35 result result VB cord-022526-j9kg00qf 2247 36 in in IN cord-022526-j9kg00qf 2247 37 a a DT cord-022526-j9kg00qf 2247 38 dysfunction dysfunction NN cord-022526-j9kg00qf 2247 39 of of IN cord-022526-j9kg00qf 2247 40 hemostatic hemostatic JJ cord-022526-j9kg00qf 2247 41 and and CC cord-022526-j9kg00qf 2247 42 circulatory circulatory JJ cord-022526-j9kg00qf 2247 43 control control NN cord-022526-j9kg00qf 2247 44 mechanisms mechanism NNS cord-022526-j9kg00qf 2247 45 , , , cord-022526-j9kg00qf 2247 46 loss loss NN cord-022526-j9kg00qf 2247 47 of of IN cord-022526-j9kg00qf 2247 48 vascular vascular JJ cord-022526-j9kg00qf 2247 49 integrity integrity NN cord-022526-j9kg00qf 2247 50 , , , cord-022526-j9kg00qf 2247 51 and and CC cord-022526-j9kg00qf 2247 52 finally finally RB cord-022526-j9kg00qf 2247 53 tissue tissue NN cord-022526-j9kg00qf 2247 54 damage damage NN cord-022526-j9kg00qf 2247 55 . . . cord-022526-j9kg00qf 2248 1 Conditions condition NNS cord-022526-j9kg00qf 2248 2 commonly commonly RB cord-022526-j9kg00qf 2248 3 associated associate VBN cord-022526-j9kg00qf 2248 4 with with IN cord-022526-j9kg00qf 2248 5 the the DT cord-022526-j9kg00qf 2248 6 development development NN cord-022526-j9kg00qf 2248 7 of of IN cord-022526-j9kg00qf 2248 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2248 9 in in IN cord-022526-j9kg00qf 2248 10 horses horse NNS cord-022526-j9kg00qf 2248 11 are be VBP cord-022526-j9kg00qf 2248 12 acute acute JJ cord-022526-j9kg00qf 2248 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2248 14 diseases disease NNS cord-022526-j9kg00qf 2248 15 , , , cord-022526-j9kg00qf 2248 16 especially especially RB cord-022526-j9kg00qf 2248 17 of of IN cord-022526-j9kg00qf 2248 18 ischemic ischemic JJ cord-022526-j9kg00qf 2248 19 and and CC cord-022526-j9kg00qf 2248 20 severe severe JJ cord-022526-j9kg00qf 2248 21 inflammatory inflammatory JJ cord-022526-j9kg00qf 2248 22 nature nature NN cord-022526-j9kg00qf 2248 23 , , , cord-022526-j9kg00qf 2248 24 and and CC cord-022526-j9kg00qf 2248 25 localized localize VBN cord-022526-j9kg00qf 2248 26 or or CC cord-022526-j9kg00qf 2248 27 generalized generalized JJ cord-022526-j9kg00qf 2248 28 infections infection NNS cord-022526-j9kg00qf 2248 29 . . . cord-022526-j9kg00qf 2249 1 Although although IN cord-022526-j9kg00qf 2249 2 measuring measure VBG cord-022526-j9kg00qf 2249 3 endotoxin endotoxin NN cord-022526-j9kg00qf 2249 4 concentrations concentration NNS cord-022526-j9kg00qf 2249 5 in in IN cord-022526-j9kg00qf 2249 6 equine equine JJ cord-022526-j9kg00qf 2249 7 plasma plasma NN cord-022526-j9kg00qf 2249 8 is be VBZ cord-022526-j9kg00qf 2249 9 possible possible JJ cord-022526-j9kg00qf 2249 10 , , , cord-022526-j9kg00qf 2249 11 this this DT cord-022526-j9kg00qf 2249 12 is be VBZ cord-022526-j9kg00qf 2249 13 not not RB cord-022526-j9kg00qf 2249 14 feasible feasible JJ cord-022526-j9kg00qf 2249 15 in in IN cord-022526-j9kg00qf 2249 16 a a DT cord-022526-j9kg00qf 2249 17 clinical clinical JJ cord-022526-j9kg00qf 2249 18 setting setting NN cord-022526-j9kg00qf 2249 19 , , , cord-022526-j9kg00qf 2249 20 and and CC cord-022526-j9kg00qf 2249 21 one one CD cord-022526-j9kg00qf 2249 22 typically typically RB cord-022526-j9kg00qf 2249 23 reaches reach VBZ cord-022526-j9kg00qf 2249 24 a a DT cord-022526-j9kg00qf 2249 25 diagnosis diagnosis NN cord-022526-j9kg00qf 2249 26 of of IN cord-022526-j9kg00qf 2249 27 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2249 28 based base VBN cord-022526-j9kg00qf 2249 29 on on IN cord-022526-j9kg00qf 2249 30 clinical clinical JJ cord-022526-j9kg00qf 2249 31 signs sign NNS cord-022526-j9kg00qf 2249 32 and and CC cord-022526-j9kg00qf 2249 33 clinicopathologic clinicopathologic NNP cord-022526-j9kg00qf 2249 34 data datum NNS cord-022526-j9kg00qf 2249 35 . . . cord-022526-j9kg00qf 2250 1 Successful successful JJ cord-022526-j9kg00qf 2250 2 treatment treatment NN cord-022526-j9kg00qf 2250 3 of of IN cord-022526-j9kg00qf 2250 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2250 5 requires require VBZ cord-022526-j9kg00qf 2250 6 resolution resolution NN cord-022526-j9kg00qf 2250 7 of of IN cord-022526-j9kg00qf 2250 8 the the DT cord-022526-j9kg00qf 2250 9 primary primary JJ cord-022526-j9kg00qf 2250 10 disease disease NN cord-022526-j9kg00qf 2250 11 process process NN cord-022526-j9kg00qf 2250 12 in in IN cord-022526-j9kg00qf 2250 13 addition addition NN cord-022526-j9kg00qf 2250 14 to to IN cord-022526-j9kg00qf 2250 15 neutralization neutralization NN cord-022526-j9kg00qf 2250 16 of of IN cord-022526-j9kg00qf 2250 17 circulating circulate VBG cord-022526-j9kg00qf 2250 18 endotoxin endotoxin NN cord-022526-j9kg00qf 2250 19 , , , cord-022526-j9kg00qf 2250 20 interference interference NN cord-022526-j9kg00qf 2250 21 with with IN cord-022526-j9kg00qf 2250 22 the the DT cord-022526-j9kg00qf 2250 23 activities activity NNS cord-022526-j9kg00qf 2250 24 of of IN cord-022526-j9kg00qf 2250 25 inflammatory inflammatory JJ cord-022526-j9kg00qf 2250 26 mediators mediator NNS cord-022526-j9kg00qf 2250 27 , , , cord-022526-j9kg00qf 2250 28 and and CC cord-022526-j9kg00qf 2250 29 general general JJ cord-022526-j9kg00qf 2250 30 supportive supportive JJ cord-022526-j9kg00qf 2250 31 care care NN cord-022526-j9kg00qf 2250 32 . . . cord-022526-j9kg00qf 2251 1 Newer new JJR cord-022526-j9kg00qf 2251 2 treatments treatment NNS cord-022526-j9kg00qf 2251 3 , , , cord-022526-j9kg00qf 2251 4 such such JJ cord-022526-j9kg00qf 2251 5 as as IN cord-022526-j9kg00qf 2251 6 blockade blockade NN cord-022526-j9kg00qf 2251 7 of of IN cord-022526-j9kg00qf 2251 8 endotoxin endotoxin NN cord-022526-j9kg00qf 2251 9 - - HYPH cord-022526-j9kg00qf 2251 10 interaction interaction NN cord-022526-j9kg00qf 2251 11 with with IN cord-022526-j9kg00qf 2251 12 cells cell NNS cord-022526-j9kg00qf 2251 13 or or CC cord-022526-j9kg00qf 2251 14 interruption interruption NN cord-022526-j9kg00qf 2251 15 of of IN cord-022526-j9kg00qf 2251 16 cell cell NN cord-022526-j9kg00qf 2251 17 signaling signal VBG cord-022526-j9kg00qf 2251 18 pathways pathway NNS cord-022526-j9kg00qf 2251 19 , , , cord-022526-j9kg00qf 2251 20 are be VBP cord-022526-j9kg00qf 2251 21 under under IN cord-022526-j9kg00qf 2251 22 investigation investigation NN cord-022526-j9kg00qf 2251 23 . . . cord-022526-j9kg00qf 2252 1 Possible possible JJ cord-022526-j9kg00qf 2252 2 sequelae sequela NNS cord-022526-j9kg00qf 2252 3 of of IN cord-022526-j9kg00qf 2252 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2252 5 include include VBP cord-022526-j9kg00qf 2252 6 DIC DIC NNP cord-022526-j9kg00qf 2252 7 , , , cord-022526-j9kg00qf 2252 8 multiple multiple JJ cord-022526-j9kg00qf 2252 9 organ organ NN cord-022526-j9kg00qf 2252 10 failure failure NN cord-022526-j9kg00qf 2252 11 , , , cord-022526-j9kg00qf 2252 12 circulatory circulatory JJ cord-022526-j9kg00qf 2252 13 failure failure NN cord-022526-j9kg00qf 2252 14 , , , cord-022526-j9kg00qf 2252 15 and and CC cord-022526-j9kg00qf 2252 16 death death NN cord-022526-j9kg00qf 2252 17 . . . cord-022526-j9kg00qf 2253 1 Frequently frequently RB cord-022526-j9kg00qf 2253 2 , , , cord-022526-j9kg00qf 2253 3 the the DT cord-022526-j9kg00qf 2253 4 outcome outcome NN cord-022526-j9kg00qf 2253 5 of of IN cord-022526-j9kg00qf 2253 6 conditions condition NNS cord-022526-j9kg00qf 2253 7 associated associate VBN cord-022526-j9kg00qf 2253 8 with with IN cord-022526-j9kg00qf 2253 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2253 10 in in IN cord-022526-j9kg00qf 2253 11 horses horse NNS cord-022526-j9kg00qf 2253 12 depends depend VBZ cord-022526-j9kg00qf 2253 13 on on IN cord-022526-j9kg00qf 2253 14 the the DT cord-022526-j9kg00qf 2253 15 severity severity NN cord-022526-j9kg00qf 2253 16 of of IN cord-022526-j9kg00qf 2253 17 associated associate VBN cord-022526-j9kg00qf 2253 18 complications complication NNS cord-022526-j9kg00qf 2253 19 ; ; : cord-022526-j9kg00qf 2253 20 for for IN cord-022526-j9kg00qf 2253 21 example example NN cord-022526-j9kg00qf 2253 22 , , , cord-022526-j9kg00qf 2253 23 renal renal JJ cord-022526-j9kg00qf 2253 24 compromise compromise NN cord-022526-j9kg00qf 2253 25 , , , cord-022526-j9kg00qf 2253 26 laminitis laminitis NN cord-022526-j9kg00qf 2253 27 , , , cord-022526-j9kg00qf 2253 28 and and CC cord-022526-j9kg00qf 2253 29 abortion abortion NN cord-022526-j9kg00qf 2253 30 . . . cord-022526-j9kg00qf 2254 1 resting rest VBG cord-022526-j9kg00qf 2254 2 state state NN cord-022526-j9kg00qf 2254 3 the the DT cord-022526-j9kg00qf 2254 4 lateral lateral JJ cord-022526-j9kg00qf 2254 5 margins margin NNS cord-022526-j9kg00qf 2254 6 of of IN cord-022526-j9kg00qf 2254 7 the the DT cord-022526-j9kg00qf 2254 8 vesicle vesicle NN cord-022526-j9kg00qf 2254 9 , , , cord-022526-j9kg00qf 2254 10 that that RB cord-022526-j9kg00qf 2254 11 is is RB cord-022526-j9kg00qf 2254 12 , , , cord-022526-j9kg00qf 2254 13 the the DT cord-022526-j9kg00qf 2254 14 buccal buccal JJ cord-022526-j9kg00qf 2254 15 mucosa mucosa NN cord-022526-j9kg00qf 2254 16 , , , cord-022526-j9kg00qf 2254 17 are be VBP cord-022526-j9kg00qf 2254 18 in in IN cord-022526-j9kg00qf 2254 19 close close JJ cord-022526-j9kg00qf 2254 20 contact contact NN cord-022526-j9kg00qf 2254 21 with with IN cord-022526-j9kg00qf 2254 22 the the DT cord-022526-j9kg00qf 2254 23 cheek cheek NN cord-022526-j9kg00qf 2254 24 teeth tooth NNS cord-022526-j9kg00qf 2254 25 . . . cord-022526-j9kg00qf 2255 1 Caudally caudally RB cord-022526-j9kg00qf 2255 2 , , , cord-022526-j9kg00qf 2255 3 the the DT cord-022526-j9kg00qf 2255 4 external external JJ cord-022526-j9kg00qf 2255 5 space space NN cord-022526-j9kg00qf 2255 6 communicates communicate VBZ cord-022526-j9kg00qf 2255 7 with with IN cord-022526-j9kg00qf 2255 8 the the DT cord-022526-j9kg00qf 2255 9 pharynx pharynx NN cord-022526-j9kg00qf 2255 10 through through IN cord-022526-j9kg00qf 2255 11 the the DT cord-022526-j9kg00qf 2255 12 aditus aditus NNP cord-022526-j9kg00qf 2255 13 pharyngis pharyngis NNP cord-022526-j9kg00qf 2255 14 . . . cord-022526-j9kg00qf 2256 1 The the DT cord-022526-j9kg00qf 2256 2 mucous mucous JJ cord-022526-j9kg00qf 2256 3 membrane membrane NN cord-022526-j9kg00qf 2256 4 of of IN cord-022526-j9kg00qf 2256 5 the the DT cord-022526-j9kg00qf 2256 6 mouth mouth NN cord-022526-j9kg00qf 2256 7 is be VBZ cord-022526-j9kg00qf 2256 8 continuous continuous JJ cord-022526-j9kg00qf 2256 9 at at IN cord-022526-j9kg00qf 2256 10 the the DT cord-022526-j9kg00qf 2256 11 margin margin NN cord-022526-j9kg00qf 2256 12 of of IN cord-022526-j9kg00qf 2256 13 the the DT cord-022526-j9kg00qf 2256 14 lips lip NNS cord-022526-j9kg00qf 2256 15 with with IN cord-022526-j9kg00qf 2256 16 the the DT cord-022526-j9kg00qf 2256 17 skin skin NN cord-022526-j9kg00qf 2256 18 and and CC cord-022526-j9kg00qf 2256 19 during during IN cord-022526-j9kg00qf 2256 20 life life NN cord-022526-j9kg00qf 2256 21 is be VBZ cord-022526-j9kg00qf 2256 22 chiefly chiefly RB cord-022526-j9kg00qf 2256 23 pink pink JJ cord-022526-j9kg00qf 2256 24 but but CC cord-022526-j9kg00qf 2256 25 can can MD cord-022526-j9kg00qf 2256 26 be be VB cord-022526-j9kg00qf 2256 27 more more RBR cord-022526-j9kg00qf 2256 28 or or CC cord-022526-j9kg00qf 2256 29 less less RBR cord-022526-j9kg00qf 2256 30 pigmented pigmented JJ cord-022526-j9kg00qf 2256 31 , , , cord-022526-j9kg00qf 2256 32 depending depend VBG cord-022526-j9kg00qf 2256 33 on on IN cord-022526-j9kg00qf 2256 34 the the DT cord-022526-j9kg00qf 2256 35 skin skin NN cord-022526-j9kg00qf 2256 36 color color NN cord-022526-j9kg00qf 2256 37 and and CC cord-022526-j9kg00qf 2256 38 the the DT cord-022526-j9kg00qf 2256 39 breed breed NN cord-022526-j9kg00qf 2256 40 type type NN cord-022526-j9kg00qf 2256 41 . . . cord-022526-j9kg00qf 2257 1 The the DT cord-022526-j9kg00qf 2257 2 lips lip NNS cord-022526-j9kg00qf 2257 3 are be VBP cord-022526-j9kg00qf 2257 4 two two CD cord-022526-j9kg00qf 2257 5 muscular muscular JJ cord-022526-j9kg00qf 2257 6 membranous membranous JJ cord-022526-j9kg00qf 2257 7 folds fold NNS cord-022526-j9kg00qf 2257 8 that that WDT cord-022526-j9kg00qf 2257 9 unite unite VBP cord-022526-j9kg00qf 2257 10 at at IN cord-022526-j9kg00qf 2257 11 angles angle NNS cord-022526-j9kg00qf 2257 12 close close RB cord-022526-j9kg00qf 2257 13 to to IN cord-022526-j9kg00qf 2257 14 the the DT cord-022526-j9kg00qf 2257 15 first first JJ cord-022526-j9kg00qf 2257 16 cheek cheek NN cord-022526-j9kg00qf 2257 17 teeth tooth NNS cord-022526-j9kg00qf 2257 18 . . . cord-022526-j9kg00qf 2258 1 Each each DT cord-022526-j9kg00qf 2258 2 lip lip NN cord-022526-j9kg00qf 2258 3 presents present VBZ cord-022526-j9kg00qf 2258 4 an an DT cord-022526-j9kg00qf 2258 5 outer outer NN cord-022526-j9kg00qf 2258 6 and and CC cord-022526-j9kg00qf 2258 7 an an DT cord-022526-j9kg00qf 2258 8 inner inner JJ cord-022526-j9kg00qf 2258 9 surface surface NN cord-022526-j9kg00qf 2258 10 . . . cord-022526-j9kg00qf 2259 1 The the DT cord-022526-j9kg00qf 2259 2 upper upper JJ cord-022526-j9kg00qf 2259 3 lip lip NN cord-022526-j9kg00qf 2259 4 has have VBZ cord-022526-j9kg00qf 2259 5 a a DT cord-022526-j9kg00qf 2259 6 shallow shallow JJ cord-022526-j9kg00qf 2259 7 median median JJ cord-022526-j9kg00qf 2259 8 furrow furrow NN cord-022526-j9kg00qf 2259 9 ( ( -LRB- cord-022526-j9kg00qf 2259 10 philtrum philtrum NN cord-022526-j9kg00qf 2259 11 ) ) -RRB- cord-022526-j9kg00qf 2259 12 ; ; : cord-022526-j9kg00qf 2259 13 the the DT cord-022526-j9kg00qf 2259 14 lower low JJR cord-022526-j9kg00qf 2259 15 lip lip NN cord-022526-j9kg00qf 2259 16 has have VBZ cord-022526-j9kg00qf 2259 17 a a DT cord-022526-j9kg00qf 2259 18 rounded rounded JJ cord-022526-j9kg00qf 2259 19 prominence prominence NN cord-022526-j9kg00qf 2259 20 or or CC cord-022526-j9kg00qf 2259 21 chin chin NNP cord-022526-j9kg00qf 2259 22 ( ( -LRB- cord-022526-j9kg00qf 2259 23 mentum mentum NNP cord-022526-j9kg00qf 2259 24 ) ) -RRB- cord-022526-j9kg00qf 2259 25 . . . cord-022526-j9kg00qf 2260 1 The the DT cord-022526-j9kg00qf 2260 2 internal internal JJ cord-022526-j9kg00qf 2260 3 surface surface NN cord-022526-j9kg00qf 2260 4 is be VBZ cord-022526-j9kg00qf 2260 5 covered cover VBN cord-022526-j9kg00qf 2260 6 with with IN cord-022526-j9kg00qf 2260 7 a a DT cord-022526-j9kg00qf 2260 8 thick thick JJ cord-022526-j9kg00qf 2260 9 mucous mucous JJ cord-022526-j9kg00qf 2260 10 membrane membrane NN cord-022526-j9kg00qf 2260 11 that that WDT cord-022526-j9kg00qf 2260 12 contains contain VBZ cord-022526-j9kg00qf 2260 13 small small JJ cord-022526-j9kg00qf 2260 14 , , , cord-022526-j9kg00qf 2260 15 pitted pitted JJ cord-022526-j9kg00qf 2260 16 surfaces surface NNS cord-022526-j9kg00qf 2260 17 that that WDT cord-022526-j9kg00qf 2260 18 are be VBP cord-022526-j9kg00qf 2260 19 the the DT cord-022526-j9kg00qf 2260 20 openings opening NNS cord-022526-j9kg00qf 2260 21 of of IN cord-022526-j9kg00qf 2260 22 the the DT cord-022526-j9kg00qf 2260 23 ducts duct NNS cord-022526-j9kg00qf 2260 24 of of IN cord-022526-j9kg00qf 2260 25 the the DT cord-022526-j9kg00qf 2260 26 labial labial JJ cord-022526-j9kg00qf 2260 27 glands gland NNS cord-022526-j9kg00qf 2260 28 . . . cord-022526-j9kg00qf 2261 1 Small small JJ cord-022526-j9kg00qf 2261 2 folds fold NNS cord-022526-j9kg00qf 2261 3 of of IN cord-022526-j9kg00qf 2261 4 the the DT cord-022526-j9kg00qf 2261 5 mucous mucous JJ cord-022526-j9kg00qf 2261 6 membrane membrane NN cord-022526-j9kg00qf 2261 7 called call VBD cord-022526-j9kg00qf 2261 8 the the DT cord-022526-j9kg00qf 2261 9 frenula frenula NNP cord-022526-j9kg00qf 2261 10 labii labii NNP cord-022526-j9kg00qf 2261 11 pass pass VB cord-022526-j9kg00qf 2261 12 from from IN cord-022526-j9kg00qf 2261 13 the the DT cord-022526-j9kg00qf 2261 14 lips lip NNS cord-022526-j9kg00qf 2261 15 to to IN cord-022526-j9kg00qf 2261 16 the the DT cord-022526-j9kg00qf 2261 17 gum gum NN cord-022526-j9kg00qf 2261 18 . . . cord-022526-j9kg00qf 2262 1 The the DT cord-022526-j9kg00qf 2262 2 free free JJ cord-022526-j9kg00qf 2262 3 border border NN cord-022526-j9kg00qf 2262 4 of of IN cord-022526-j9kg00qf 2262 5 the the DT cord-022526-j9kg00qf 2262 6 lip lip NN cord-022526-j9kg00qf 2262 7 is be VBZ cord-022526-j9kg00qf 2262 8 dense dense JJ cord-022526-j9kg00qf 2262 9 and and CC cord-022526-j9kg00qf 2262 10 bears bear VBZ cord-022526-j9kg00qf 2262 11 short short JJ cord-022526-j9kg00qf 2262 12 , , , cord-022526-j9kg00qf 2262 13 stiff stiff JJ cord-022526-j9kg00qf 2262 14 hairs hair NNS cord-022526-j9kg00qf 2262 15 . . . cord-022526-j9kg00qf 2263 1 The the DT cord-022526-j9kg00qf 2263 2 arteries artery NNS cord-022526-j9kg00qf 2263 3 of of IN cord-022526-j9kg00qf 2263 4 the the DT cord-022526-j9kg00qf 2263 5 mouth mouth NN cord-022526-j9kg00qf 2263 6 are be VBP cord-022526-j9kg00qf 2263 7 derived derive VBN cord-022526-j9kg00qf 2263 8 from from IN cord-022526-j9kg00qf 2263 9 the the DT cord-022526-j9kg00qf 2263 10 maxillary maxillary JJ cord-022526-j9kg00qf 2263 11 , , , cord-022526-j9kg00qf 2263 12 mandibular mandibular JJ cord-022526-j9kg00qf 2263 13 , , , cord-022526-j9kg00qf 2263 14 labial labial NNP cord-022526-j9kg00qf 2263 15 , , , cord-022526-j9kg00qf 2263 16 and and CC cord-022526-j9kg00qf 2263 17 sphenopalatine sphenopalatine NNP cord-022526-j9kg00qf 2263 18 arteries artery NNS cord-022526-j9kg00qf 2263 19 of of IN cord-022526-j9kg00qf 2263 20 the the DT cord-022526-j9kg00qf 2263 21 major major JJ cord-022526-j9kg00qf 2263 22 palatine palatine NNP cord-022526-j9kg00qf 2263 23 artery artery NN cord-022526-j9kg00qf 2263 24 . . . cord-022526-j9kg00qf 2264 1 The the DT cord-022526-j9kg00qf 2264 2 veins vein NNS cord-022526-j9kg00qf 2264 3 drain drain VBP cord-022526-j9kg00qf 2264 4 chiefly chiefly RB cord-022526-j9kg00qf 2264 5 to to IN cord-022526-j9kg00qf 2264 6 the the DT cord-022526-j9kg00qf 2264 7 lingual lingual JJ cord-022526-j9kg00qf 2264 8 facial facial JJ cord-022526-j9kg00qf 2264 9 vein vein NN cord-022526-j9kg00qf 2264 10 . . . cord-022526-j9kg00qf 2265 1 Sensory sensory JJ cord-022526-j9kg00qf 2265 2 nerves nerve NNS cord-022526-j9kg00qf 2265 3 originate originate VBP cord-022526-j9kg00qf 2265 4 from from IN cord-022526-j9kg00qf 2265 5 the the DT cord-022526-j9kg00qf 2265 6 trigeminal trigeminal JJ cord-022526-j9kg00qf 2265 7 nerve nerve NN cord-022526-j9kg00qf 2265 8 ( ( -LRB- cord-022526-j9kg00qf 2265 9 cranial cranial JJ cord-022526-j9kg00qf 2265 10 nerve nerve NN cord-022526-j9kg00qf 2265 11 V v NN cord-022526-j9kg00qf 2265 12 ) ) -RRB- cord-022526-j9kg00qf 2265 13 and and CC cord-022526-j9kg00qf 2265 14 the the DT cord-022526-j9kg00qf 2265 15 motor motor NN cord-022526-j9kg00qf 2265 16 nerves nerve NNS cord-022526-j9kg00qf 2265 17 from from IN cord-022526-j9kg00qf 2265 18 the the DT cord-022526-j9kg00qf 2265 19 facial facial JJ cord-022526-j9kg00qf 2265 20 nerve nerve NN cord-022526-j9kg00qf 2265 21 ( ( -LRB- cord-022526-j9kg00qf 2265 22 VII VII NNP cord-022526-j9kg00qf 2265 23 ) ) -RRB- cord-022526-j9kg00qf 2265 24 . . . cord-022526-j9kg00qf 2266 1 The the DT cord-022526-j9kg00qf 2266 2 cheeks cheek NNS cord-022526-j9kg00qf 2266 3 spread spread VBD cord-022526-j9kg00qf 2266 4 back back RB cord-022526-j9kg00qf 2266 5 from from IN cord-022526-j9kg00qf 2266 6 the the DT cord-022526-j9kg00qf 2266 7 lips lip NNS cord-022526-j9kg00qf 2266 8 and and CC cord-022526-j9kg00qf 2266 9 form form VB cord-022526-j9kg00qf 2266 10 both both DT cord-022526-j9kg00qf 2266 11 sides side NNS cord-022526-j9kg00qf 2266 12 of of IN cord-022526-j9kg00qf 2266 13 the the DT cord-022526-j9kg00qf 2266 14 mouth mouth NN cord-022526-j9kg00qf 2266 15 and and CC cord-022526-j9kg00qf 2266 16 are be VBP cord-022526-j9kg00qf 2266 17 attached attach VBN cord-022526-j9kg00qf 2266 18 to to IN cord-022526-j9kg00qf 2266 19 the the DT cord-022526-j9kg00qf 2266 20 alveolar alveolar JJ cord-022526-j9kg00qf 2266 21 borders border NNS cord-022526-j9kg00qf 2266 22 of of IN cord-022526-j9kg00qf 2266 23 the the DT cord-022526-j9kg00qf 2266 24 bones bone NNS cord-022526-j9kg00qf 2266 25 of of IN cord-022526-j9kg00qf 2266 26 the the DT cord-022526-j9kg00qf 2266 27 jaws jaw NNS cord-022526-j9kg00qf 2266 28 . . . cord-022526-j9kg00qf 2267 1 The the DT cord-022526-j9kg00qf 2267 2 cheeks cheek NNS cord-022526-j9kg00qf 2267 3 are be VBP cord-022526-j9kg00qf 2267 4 composed compose VBN cord-022526-j9kg00qf 2267 5 of of IN cord-022526-j9kg00qf 2267 6 skin skin NN cord-022526-j9kg00qf 2267 7 and and CC cord-022526-j9kg00qf 2267 8 muscular muscular JJ cord-022526-j9kg00qf 2267 9 and and CC cord-022526-j9kg00qf 2267 10 glandular glandular JJ cord-022526-j9kg00qf 2267 11 layers layer NNS cord-022526-j9kg00qf 2267 12 and and CC cord-022526-j9kg00qf 2267 13 then then RB cord-022526-j9kg00qf 2267 14 the the DT cord-022526-j9kg00qf 2267 15 internal internal JJ cord-022526-j9kg00qf 2267 16 mucous mucous JJ cord-022526-j9kg00qf 2267 17 membrane membrane NN cord-022526-j9kg00qf 2267 18 . . . cord-022526-j9kg00qf 2268 1 The the DT cord-022526-j9kg00qf 2268 2 skin skin NN cord-022526-j9kg00qf 2268 3 is be VBZ cord-022526-j9kg00qf 2268 4 thin thin JJ cord-022526-j9kg00qf 2268 5 and and CC cord-022526-j9kg00qf 2268 6 pliable pliable JJ cord-022526-j9kg00qf 2268 7 . . . cord-022526-j9kg00qf 2269 1 In in IN cord-022526-j9kg00qf 2269 2 contrast contrast NN cord-022526-j9kg00qf 2269 3 , , , cord-022526-j9kg00qf 2269 4 the the DT cord-022526-j9kg00qf 2269 5 oral oral JJ cord-022526-j9kg00qf 2269 6 mucous mucous JJ cord-022526-j9kg00qf 2269 7 membrane membrane NN cord-022526-j9kg00qf 2269 8 is be VBZ cord-022526-j9kg00qf 2269 9 dense dense JJ cord-022526-j9kg00qf 2269 10 and and CC cord-022526-j9kg00qf 2269 11 in in IN cord-022526-j9kg00qf 2269 12 many many JJ cord-022526-j9kg00qf 2269 13 areas area NNS cord-022526-j9kg00qf 2269 14 of of IN cord-022526-j9kg00qf 2269 15 the the DT cord-022526-j9kg00qf 2269 16 oral oral JJ cord-022526-j9kg00qf 2269 17 cavity cavity NN cord-022526-j9kg00qf 2269 18 is be VBZ cord-022526-j9kg00qf 2269 19 attached attach VBN cord-022526-j9kg00qf 2269 20 firmly firmly RB cord-022526-j9kg00qf 2269 21 to to IN cord-022526-j9kg00qf 2269 22 the the DT cord-022526-j9kg00qf 2269 23 periosteum periosteum NN cord-022526-j9kg00qf 2269 24 so so IN cord-022526-j9kg00qf 2269 25 that that DT cord-022526-j9kg00qf 2269 26 construction construction NN cord-022526-j9kg00qf 2269 27 of of IN cord-022526-j9kg00qf 2269 28 oral oral JJ cord-022526-j9kg00qf 2269 29 mucosal mucosal JJ cord-022526-j9kg00qf 2269 30 flaps flap NNS cord-022526-j9kg00qf 2269 31 can can MD cord-022526-j9kg00qf 2269 32 be be VB cord-022526-j9kg00qf 2269 33 achieved achieve VBN cord-022526-j9kg00qf 2269 34 only only RB cord-022526-j9kg00qf 2269 35 by by IN cord-022526-j9kg00qf 2269 36 horizontal horizontal JJ cord-022526-j9kg00qf 2269 37 division division NN cord-022526-j9kg00qf 2269 38 of of IN cord-022526-j9kg00qf 2269 39 the the DT cord-022526-j9kg00qf 2269 40 periosteal periosteal NN cord-022526-j9kg00qf 2269 41 attachment attachment NN cord-022526-j9kg00qf 2269 42 . . . cord-022526-j9kg00qf 2270 1 Such such JJ cord-022526-j9kg00qf 2270 2 a a DT cord-022526-j9kg00qf 2270 3 feature feature NN cord-022526-j9kg00qf 2270 4 is be VBZ cord-022526-j9kg00qf 2270 5 important important JJ cord-022526-j9kg00qf 2270 6 in in IN cord-022526-j9kg00qf 2270 7 reconstructive reconstructive JJ cord-022526-j9kg00qf 2270 8 techniques technique NNS cord-022526-j9kg00qf 2270 9 applied apply VBN cord-022526-j9kg00qf 2270 10 to to IN cord-022526-j9kg00qf 2270 11 the the DT cord-022526-j9kg00qf 2270 12 oral oral JJ cord-022526-j9kg00qf 2270 13 cavity cavity NN cord-022526-j9kg00qf 2270 14 . . . cord-022526-j9kg00qf 2271 1 The the DT cord-022526-j9kg00qf 2271 2 blood blood NN cord-022526-j9kg00qf 2271 3 supply supply NN cord-022526-j9kg00qf 2271 4 to to IN cord-022526-j9kg00qf 2271 5 the the DT cord-022526-j9kg00qf 2271 6 cheeks cheek NNS cord-022526-j9kg00qf 2271 7 comes come VBZ cord-022526-j9kg00qf 2271 8 from from IN cord-022526-j9kg00qf 2271 9 the the DT cord-022526-j9kg00qf 2271 10 facial facial JJ cord-022526-j9kg00qf 2271 11 and and CC cord-022526-j9kg00qf 2271 12 buccal buccal JJ cord-022526-j9kg00qf 2271 13 arteries artery NNS cord-022526-j9kg00qf 2271 14 and and CC cord-022526-j9kg00qf 2271 15 the the DT cord-022526-j9kg00qf 2271 16 sensory sensory JJ cord-022526-j9kg00qf 2271 17 nerves nerve NNS cord-022526-j9kg00qf 2271 18 from from IN cord-022526-j9kg00qf 2271 19 the the DT cord-022526-j9kg00qf 2271 20 trigeminal trigeminal JJ cord-022526-j9kg00qf 2271 21 and and CC cord-022526-j9kg00qf 2271 22 motor motor NN cord-022526-j9kg00qf 2271 23 nerves nerve NNS cord-022526-j9kg00qf 2271 24 from from IN cord-022526-j9kg00qf 2271 25 the the DT cord-022526-j9kg00qf 2271 26 facial facial JJ cord-022526-j9kg00qf 2271 27 nerve nerve NN cord-022526-j9kg00qf 2271 28 . . . cord-022526-j9kg00qf 2272 1 The the DT cord-022526-j9kg00qf 2272 2 hard hard JJ cord-022526-j9kg00qf 2272 3 palate palate NN cord-022526-j9kg00qf 2272 4 ( ( -LRB- cord-022526-j9kg00qf 2272 5 palatum palatum NNP cord-022526-j9kg00qf 2272 6 durum durum NNP cord-022526-j9kg00qf 2272 7 ) ) -RRB- cord-022526-j9kg00qf 2272 8 is be VBZ cord-022526-j9kg00qf 2272 9 bounded bound VBN cord-022526-j9kg00qf 2272 10 rostrally rostrally RB cord-022526-j9kg00qf 2272 11 and and CC cord-022526-j9kg00qf 2272 12 laterally laterally RB cord-022526-j9kg00qf 2272 13 by by IN cord-022526-j9kg00qf 2272 14 the the DT cord-022526-j9kg00qf 2272 15 alveolar alveolar JJ cord-022526-j9kg00qf 2272 16 arches arch NNS cord-022526-j9kg00qf 2272 17 and and CC cord-022526-j9kg00qf 2272 18 is be VBZ cord-022526-j9kg00qf 2272 19 continuous continuous JJ cord-022526-j9kg00qf 2272 20 with with IN cord-022526-j9kg00qf 2272 21 the the DT cord-022526-j9kg00qf 2272 22 soft soft JJ cord-022526-j9kg00qf 2272 23 palate palate NN cord-022526-j9kg00qf 2272 24 caudally caudally RB cord-022526-j9kg00qf 2272 25 . . . cord-022526-j9kg00qf 2273 1 The the DT cord-022526-j9kg00qf 2273 2 hard hard JJ cord-022526-j9kg00qf 2273 3 palate palate NN cord-022526-j9kg00qf 2273 4 has have VBZ cord-022526-j9kg00qf 2273 5 a a DT cord-022526-j9kg00qf 2273 6 central central JJ cord-022526-j9kg00qf 2273 7 raphe raphe NN cord-022526-j9kg00qf 2273 8 that that WDT cord-022526-j9kg00qf 2273 9 divides divide VBZ cord-022526-j9kg00qf 2273 10 the the DT cord-022526-j9kg00qf 2273 11 surface surface NN cord-022526-j9kg00qf 2273 12 into into IN cord-022526-j9kg00qf 2273 13 two two CD cord-022526-j9kg00qf 2273 14 equal equal JJ cord-022526-j9kg00qf 2273 15 portions portion NNS cord-022526-j9kg00qf 2273 16 . . . cord-022526-j9kg00qf 2273 17 _SP cord-022526-j9kg00qf 2274 1 The the DT cord-022526-j9kg00qf 2274 2 word word NN cord-022526-j9kg00qf 2274 3 mouth mouth NN cord-022526-j9kg00qf 2274 4 is be VBZ cord-022526-j9kg00qf 2274 5 used use VBN cord-022526-j9kg00qf 2274 6 commonly commonly RB cord-022526-j9kg00qf 2274 7 to to TO cord-022526-j9kg00qf 2274 8 signify signify VB cord-022526-j9kg00qf 2274 9 the the DT cord-022526-j9kg00qf 2274 10 first first JJ cord-022526-j9kg00qf 2274 11 part part NN cord-022526-j9kg00qf 2274 12 of of IN cord-022526-j9kg00qf 2274 13 the the DT cord-022526-j9kg00qf 2274 14 alimentary alimentary JJ cord-022526-j9kg00qf 2274 15 canal canal NN cord-022526-j9kg00qf 2274 16 or or CC cord-022526-j9kg00qf 2274 17 the the DT cord-022526-j9kg00qf 2274 18 entrance entrance NN cord-022526-j9kg00qf 2274 19 to to IN cord-022526-j9kg00qf 2274 20 it -PRON- PRP cord-022526-j9kg00qf 2274 21 . . . cord-022526-j9kg00qf 2275 1 1 1 LS cord-022526-j9kg00qf 2276 1 The the DT cord-022526-j9kg00qf 2276 2 mouth mouth NN cord-022526-j9kg00qf 2276 3 is be VBZ cord-022526-j9kg00qf 2276 4 bounded bound VBN cord-022526-j9kg00qf 2276 5 laterally laterally RB cord-022526-j9kg00qf 2276 6 by by IN cord-022526-j9kg00qf 2276 7 the the DT cord-022526-j9kg00qf 2276 8 cheeks cheek NNS cord-022526-j9kg00qf 2276 9 , , , cord-022526-j9kg00qf 2276 10 dorsally dorsally RB cord-022526-j9kg00qf 2276 11 by by IN cord-022526-j9kg00qf 2276 12 the the DT cord-022526-j9kg00qf 2276 13 palate palate NN cord-022526-j9kg00qf 2276 14 , , , cord-022526-j9kg00qf 2276 15 and and CC cord-022526-j9kg00qf 2276 16 ventrally ventrally RB cord-022526-j9kg00qf 2276 17 by by IN cord-022526-j9kg00qf 2276 18 the the DT cord-022526-j9kg00qf 2276 19 body body NN cord-022526-j9kg00qf 2276 20 of of IN cord-022526-j9kg00qf 2276 21 the the DT cord-022526-j9kg00qf 2276 22 mandible mandible NN cord-022526-j9kg00qf 2276 23 and and CC cord-022526-j9kg00qf 2276 24 by by IN cord-022526-j9kg00qf 2276 25 the the DT cord-022526-j9kg00qf 2276 26 mylohyoideus mylohyoideus NN cord-022526-j9kg00qf 2276 27 muscles muscle NNS cord-022526-j9kg00qf 2276 28 . . . cord-022526-j9kg00qf 2277 1 The the DT cord-022526-j9kg00qf 2277 2 caudal caudal JJ cord-022526-j9kg00qf 2277 3 margin margin NN cord-022526-j9kg00qf 2277 4 is be VBZ cord-022526-j9kg00qf 2277 5 the the DT cord-022526-j9kg00qf 2277 6 soft soft JJ cord-022526-j9kg00qf 2277 7 palate palate NN cord-022526-j9kg00qf 2277 8 . . . cord-022526-j9kg00qf 2278 1 The the DT cord-022526-j9kg00qf 2278 2 mouth mouth NN cord-022526-j9kg00qf 2278 3 of of IN cord-022526-j9kg00qf 2278 4 the the DT cord-022526-j9kg00qf 2278 5 horse horse NN cord-022526-j9kg00qf 2278 6 is be VBZ cord-022526-j9kg00qf 2278 7 long long JJ cord-022526-j9kg00qf 2278 8 and and CC cord-022526-j9kg00qf 2278 9 cylindric cylindric JJ cord-022526-j9kg00qf 2278 10 , , , cord-022526-j9kg00qf 2278 11 and and CC cord-022526-j9kg00qf 2278 12 when when WRB cord-022526-j9kg00qf 2278 13 the the DT cord-022526-j9kg00qf 2278 14 lips lip NNS cord-022526-j9kg00qf 2278 15 are be VBP cord-022526-j9kg00qf 2278 16 closed close VBN cord-022526-j9kg00qf 2278 17 , , , cord-022526-j9kg00qf 2278 18 the the DT cord-022526-j9kg00qf 2278 19 contained contain VBN cord-022526-j9kg00qf 2278 20 structures structure NNS cord-022526-j9kg00qf 2278 21 almost almost RB cord-022526-j9kg00qf 2278 22 fill fill VBP cord-022526-j9kg00qf 2278 23 the the DT cord-022526-j9kg00qf 2278 24 cavity cavity NN cord-022526-j9kg00qf 2278 25 . . . cord-022526-j9kg00qf 2279 1 A a DT cord-022526-j9kg00qf 2279 2 small small JJ cord-022526-j9kg00qf 2279 3 space space NN cord-022526-j9kg00qf 2279 4 remains remain VBZ cord-022526-j9kg00qf 2279 5 between between IN cord-022526-j9kg00qf 2279 6 the the DT cord-022526-j9kg00qf 2279 7 root root NN cord-022526-j9kg00qf 2279 8 of of IN cord-022526-j9kg00qf 2279 9 the the DT cord-022526-j9kg00qf 2279 10 tongue tongue NN cord-022526-j9kg00qf 2279 11 and and CC cord-022526-j9kg00qf 2279 12 the the DT cord-022526-j9kg00qf 2279 13 epiglottis epiglottis NN cord-022526-j9kg00qf 2279 14 and and CC cord-022526-j9kg00qf 2279 15 is be VBZ cord-022526-j9kg00qf 2279 16 termed term VBN cord-022526-j9kg00qf 2279 17 the the DT cord-022526-j9kg00qf 2279 18 oropharynx oropharynx NN cord-022526-j9kg00qf 2279 19 . . . cord-022526-j9kg00qf 2280 1 The the DT cord-022526-j9kg00qf 2280 2 cavity cavity NN cord-022526-j9kg00qf 2280 3 of of IN cord-022526-j9kg00qf 2280 4 the the DT cord-022526-j9kg00qf 2280 5 mouth mouth NN cord-022526-j9kg00qf 2280 6 is be VBZ cord-022526-j9kg00qf 2280 7 subdivided subdivide VBN cord-022526-j9kg00qf 2280 8 into into IN cord-022526-j9kg00qf 2280 9 sections section NNS cord-022526-j9kg00qf 2280 10 by by IN cord-022526-j9kg00qf 2280 11 the the DT cord-022526-j9kg00qf 2280 12 teeth tooth NNS cord-022526-j9kg00qf 2280 13 . . . cord-022526-j9kg00qf 2281 1 The the DT cord-022526-j9kg00qf 2281 2 space space NN cord-022526-j9kg00qf 2281 3 external external JJ cord-022526-j9kg00qf 2281 4 to to IN cord-022526-j9kg00qf 2281 5 the the DT cord-022526-j9kg00qf 2281 6 teeth tooth NNS cord-022526-j9kg00qf 2281 7 and and CC cord-022526-j9kg00qf 2281 8 enclosed enclose VBN cord-022526-j9kg00qf 2281 9 by by IN cord-022526-j9kg00qf 2281 10 the the DT cord-022526-j9kg00qf 2281 11 lips lip NNS cord-022526-j9kg00qf 2281 12 is be VBZ cord-022526-j9kg00qf 2281 13 termed term VBN cord-022526-j9kg00qf 2281 14 the the DT cord-022526-j9kg00qf 2281 15 vesicle vesicle NN cord-022526-j9kg00qf 2281 16 of of IN cord-022526-j9kg00qf 2281 17 the the DT cord-022526-j9kg00qf 2281 18 mouth mouth NN cord-022526-j9kg00qf 2281 19 , , , cord-022526-j9kg00qf 2281 20 and and CC cord-022526-j9kg00qf 2281 21 in in IN cord-022526-j9kg00qf 2281 22 the the DT cord-022526-j9kg00qf 2281 23 enter enter NN cord-022526-j9kg00qf 2281 24 the the DT cord-022526-j9kg00qf 2281 25 nose nose NN cord-022526-j9kg00qf 2281 26 from from IN cord-022526-j9kg00qf 2281 27 the the DT cord-022526-j9kg00qf 2281 28 glands gland NNS cord-022526-j9kg00qf 2281 29 of of IN cord-022526-j9kg00qf 2281 30 the the DT cord-022526-j9kg00qf 2281 31 vomeronasal vomeronasal NN cord-022526-j9kg00qf 2281 32 duct duct NN cord-022526-j9kg00qf 2281 33 . . . cord-022526-j9kg00qf 2282 1 To to TO cord-022526-j9kg00qf 2282 2 what what WDT cord-022526-j9kg00qf 2282 3 extent extent NN cord-022526-j9kg00qf 2282 4 these these DT cord-022526-j9kg00qf 2282 5 secretions secretion NNS cord-022526-j9kg00qf 2282 6 aid aid NN cord-022526-j9kg00qf 2282 7 in in IN cord-022526-j9kg00qf 2282 8 pheromone pheromone NN cord-022526-j9kg00qf 2282 9 reception reception NN cord-022526-j9kg00qf 2282 10 is be VBZ cord-022526-j9kg00qf 2282 11 not not RB cord-022526-j9kg00qf 2282 12 known know VBN cord-022526-j9kg00qf 2282 13 . . . cord-022526-j9kg00qf 2283 1 2 2 LS cord-022526-j9kg00qf 2284 1 That that DT cord-022526-j9kg00qf 2284 2 portion portion NN cord-022526-j9kg00qf 2284 3 of of IN cord-022526-j9kg00qf 2284 4 the the DT cord-022526-j9kg00qf 2284 5 palatine palatine NNP cord-022526-j9kg00qf 2284 6 mucosa mucosa NN cord-022526-j9kg00qf 2284 7 immediately immediately RB cord-022526-j9kg00qf 2284 8 behind behind IN cord-022526-j9kg00qf 2284 9 the the DT cord-022526-j9kg00qf 2284 10 incisor incisor NN cord-022526-j9kg00qf 2284 11 teeth tooth NNS cord-022526-j9kg00qf 2284 12 frequently frequently RB cord-022526-j9kg00qf 2284 13 is be VBZ cord-022526-j9kg00qf 2284 14 swollen swollen JJ cord-022526-j9kg00qf 2284 15 ( ( -LRB- cord-022526-j9kg00qf 2284 16 lampas lampa NNS cord-022526-j9kg00qf 2284 17 ) ) -RRB- cord-022526-j9kg00qf 2284 18 during during IN cord-022526-j9kg00qf 2284 19 eruption eruption NN cord-022526-j9kg00qf 2284 20 of of IN cord-022526-j9kg00qf 2284 21 the the DT cord-022526-j9kg00qf 2284 22 permanent permanent JJ cord-022526-j9kg00qf 2284 23 teeth tooth NNS cord-022526-j9kg00qf 2284 24 . . . cord-022526-j9kg00qf 2285 1 This this DT cord-022526-j9kg00qf 2285 2 swelling swelling NN cord-022526-j9kg00qf 2285 3 is be VBZ cord-022526-j9kg00qf 2285 4 physiologic physiologic JJ cord-022526-j9kg00qf 2285 5 and and CC cord-022526-j9kg00qf 2285 6 not not RB cord-022526-j9kg00qf 2285 7 pathologic pathologic JJ cord-022526-j9kg00qf 2285 8 . . . cord-022526-j9kg00qf 2286 1 The the DT cord-022526-j9kg00qf 2286 2 tongue tongue NN cord-022526-j9kg00qf 2286 3 is be VBZ cord-022526-j9kg00qf 2286 4 situated situate VBN cord-022526-j9kg00qf 2286 5 on on IN cord-022526-j9kg00qf 2286 6 the the DT cord-022526-j9kg00qf 2286 7 floor floor NN cord-022526-j9kg00qf 2286 8 of of IN cord-022526-j9kg00qf 2286 9 the the DT cord-022526-j9kg00qf 2286 10 mouth mouth NN cord-022526-j9kg00qf 2286 11 between between IN cord-022526-j9kg00qf 2286 12 the the DT cord-022526-j9kg00qf 2286 13 bodies body NNS cord-022526-j9kg00qf 2286 14 of of IN cord-022526-j9kg00qf 2286 15 the the DT cord-022526-j9kg00qf 2286 16 mandible mandible NN cord-022526-j9kg00qf 2286 17 and and CC cord-022526-j9kg00qf 2286 18 is be VBZ cord-022526-j9kg00qf 2286 19 supported support VBN cord-022526-j9kg00qf 2286 20 by by IN cord-022526-j9kg00qf 2286 21 the the DT cord-022526-j9kg00qf 2286 22 sling sling NN cord-022526-j9kg00qf 2286 23 formed form VBN cord-022526-j9kg00qf 2286 24 by by IN cord-022526-j9kg00qf 2286 25 the the DT cord-022526-j9kg00qf 2286 26 mylohyoideus mylohyoideus NN cord-022526-j9kg00qf 2286 27 muscles muscle NNS cord-022526-j9kg00qf 2286 28 . . . cord-022526-j9kg00qf 2287 1 The the DT cord-022526-j9kg00qf 2287 2 root root NN cord-022526-j9kg00qf 2287 3 of of IN cord-022526-j9kg00qf 2287 4 the the DT cord-022526-j9kg00qf 2287 5 tongue tongue NN cord-022526-j9kg00qf 2287 6 is be VBZ cord-022526-j9kg00qf 2287 7 attached attach VBN cord-022526-j9kg00qf 2287 8 to to IN cord-022526-j9kg00qf 2287 9 the the DT cord-022526-j9kg00qf 2287 10 hyoid hyoid NN cord-022526-j9kg00qf 2287 11 bone bone NN cord-022526-j9kg00qf 2287 12 , , , cord-022526-j9kg00qf 2287 13 soft soft JJ cord-022526-j9kg00qf 2287 14 palate palate NN cord-022526-j9kg00qf 2287 15 , , , cord-022526-j9kg00qf 2287 16 and and CC cord-022526-j9kg00qf 2287 17 pharynx pharynx NN cord-022526-j9kg00qf 2287 18 . . . cord-022526-j9kg00qf 2288 1 The the DT cord-022526-j9kg00qf 2288 2 upper upper JJ cord-022526-j9kg00qf 2288 3 surface surface NN cord-022526-j9kg00qf 2288 4 and and CC cord-022526-j9kg00qf 2288 5 the the DT cord-022526-j9kg00qf 2288 6 rostral rostral JJ cord-022526-j9kg00qf 2288 7 portion portion NN cord-022526-j9kg00qf 2288 8 of of IN cord-022526-j9kg00qf 2288 9 the the DT cord-022526-j9kg00qf 2288 10 tongue tongue NN cord-022526-j9kg00qf 2288 11 are be VBP cord-022526-j9kg00qf 2288 12 free free JJ cord-022526-j9kg00qf 2288 13 ; ; : cord-022526-j9kg00qf 2288 14 the the DT cord-022526-j9kg00qf 2288 15 body body NN cord-022526-j9kg00qf 2288 16 of of IN cord-022526-j9kg00qf 2288 17 the the DT cord-022526-j9kg00qf 2288 18 tongue tongue NN cord-022526-j9kg00qf 2288 19 has have VBZ cord-022526-j9kg00qf 2288 20 three three CD cord-022526-j9kg00qf 2288 21 surfaces surface NNS cord-022526-j9kg00qf 2288 22 . . . cord-022526-j9kg00qf 2289 1 The the DT cord-022526-j9kg00qf 2289 2 apex apex NN cord-022526-j9kg00qf 2289 3 of of IN cord-022526-j9kg00qf 2289 4 the the DT cord-022526-j9kg00qf 2289 5 tongue tongue NN cord-022526-j9kg00qf 2289 6 is be VBZ cord-022526-j9kg00qf 2289 7 spatulate spatulate JJ cord-022526-j9kg00qf 2289 8 and and CC cord-022526-j9kg00qf 2289 9 has have VBZ cord-022526-j9kg00qf 2289 10 a a DT cord-022526-j9kg00qf 2289 11 rounded rounded JJ cord-022526-j9kg00qf 2289 12 border border NN cord-022526-j9kg00qf 2289 13 . . . cord-022526-j9kg00qf 2290 1 The the DT cord-022526-j9kg00qf 2290 2 mucous mucous JJ cord-022526-j9kg00qf 2290 3 membrane membrane NN cord-022526-j9kg00qf 2290 4 adheres adhere VBZ cord-022526-j9kg00qf 2290 5 intimately intimately RB cord-022526-j9kg00qf 2290 6 to to IN cord-022526-j9kg00qf 2290 7 the the DT cord-022526-j9kg00qf 2290 8 adjacent adjacent JJ cord-022526-j9kg00qf 2290 9 structure structure NN cord-022526-j9kg00qf 2290 10 and and CC cord-022526-j9kg00qf 2290 11 on on IN cord-022526-j9kg00qf 2290 12 the the DT cord-022526-j9kg00qf 2290 13 dorsum dorsum NN cord-022526-j9kg00qf 2290 14 is be VBZ cord-022526-j9kg00qf 2290 15 dense dense JJ cord-022526-j9kg00qf 2290 16 and and CC cord-022526-j9kg00qf 2290 17 thick thick JJ cord-022526-j9kg00qf 2290 18 . . . cord-022526-j9kg00qf 2291 1 The the DT cord-022526-j9kg00qf 2291 2 lingual lingual JJ cord-022526-j9kg00qf 2291 3 and and CC cord-022526-j9kg00qf 2291 4 sublingual sublingual JJ cord-022526-j9kg00qf 2291 5 arteries artery NNS cord-022526-j9kg00qf 2291 6 supply supply VBP cord-022526-j9kg00qf 2291 7 the the DT cord-022526-j9kg00qf 2291 8 tongue tongue NN cord-022526-j9kg00qf 2291 9 from from IN cord-022526-j9kg00qf 2291 10 the the DT cord-022526-j9kg00qf 2291 11 linguofacial linguofacial JJ cord-022526-j9kg00qf 2291 12 trunk trunk NN cord-022526-j9kg00qf 2291 13 and and CC cord-022526-j9kg00qf 2291 14 matching match VBG cord-022526-j9kg00qf 2291 15 veins vein NNS cord-022526-j9kg00qf 2291 16 . . . cord-022526-j9kg00qf 2292 1 The the DT cord-022526-j9kg00qf 2292 2 linguofacial linguofacial JJ cord-022526-j9kg00qf 2292 3 trunk trunk NN cord-022526-j9kg00qf 2292 4 drains drain VBZ cord-022526-j9kg00qf 2292 5 into into IN cord-022526-j9kg00qf 2292 6 the the DT cord-022526-j9kg00qf 2292 7 linguofacial linguofacial JJ cord-022526-j9kg00qf 2292 8 vein vein NN cord-022526-j9kg00qf 2292 9 . . . cord-022526-j9kg00qf 2293 1 The the DT cord-022526-j9kg00qf 2293 2 lingual lingual JJ cord-022526-j9kg00qf 2293 3 muscles muscle NNS cord-022526-j9kg00qf 2293 4 are be VBP cord-022526-j9kg00qf 2293 5 innervated innervate VBN cord-022526-j9kg00qf 2293 6 by by IN cord-022526-j9kg00qf 2293 7 the the DT cord-022526-j9kg00qf 2293 8 hypoglossal hypoglossal NN cord-022526-j9kg00qf 2293 9 nerve nerve NN cord-022526-j9kg00qf 2293 10 ( ( -LRB- cord-022526-j9kg00qf 2293 11 XII XII NNP cord-022526-j9kg00qf 2293 12 ) ) -RRB- cord-022526-j9kg00qf 2293 13 and and CC cord-022526-j9kg00qf 2293 14 the the DT cord-022526-j9kg00qf 2293 15 sensory sensory JJ cord-022526-j9kg00qf 2293 16 supply supply NN cord-022526-j9kg00qf 2293 17 is be VBZ cord-022526-j9kg00qf 2293 18 from from IN cord-022526-j9kg00qf 2293 19 the the DT cord-022526-j9kg00qf 2293 20 lingual lingual JJ cord-022526-j9kg00qf 2293 21 and and CC cord-022526-j9kg00qf 2293 22 glossopharyngeal glossopharyngeal JJ cord-022526-j9kg00qf 2293 23 ( ( -LRB- cord-022526-j9kg00qf 2293 24 IX IX NNP cord-022526-j9kg00qf 2293 25 ) ) -RRB- cord-022526-j9kg00qf 2293 26 nerves nerve NNS cord-022526-j9kg00qf 2293 27 . . . cord-022526-j9kg00qf 2294 1 The the DT cord-022526-j9kg00qf 2294 2 formula formula NN cord-022526-j9kg00qf 2294 3 for for IN cord-022526-j9kg00qf 2294 4 the the DT cord-022526-j9kg00qf 2294 5 deciduous deciduous JJ cord-022526-j9kg00qf 2294 6 teeth tooth NNS cord-022526-j9kg00qf 2294 7 of of IN cord-022526-j9kg00qf 2294 8 the the DT cord-022526-j9kg00qf 2294 9 horse horse NN cord-022526-j9kg00qf 2294 10 is be VBZ cord-022526-j9kg00qf 2294 11 2 2 CD cord-022526-j9kg00qf 2294 12 times time NNS cord-022526-j9kg00qf 2294 13 I3 I3 NNP cord-022526-j9kg00qf 2294 14 - - HYPH cord-022526-j9kg00qf 2294 15 3 3 CD cord-022526-j9kg00qf 2294 16 C0 c0 NN cord-022526-j9kg00qf 2294 17 - - HYPH cord-022526-j9kg00qf 2294 18 0 0 CD cord-022526-j9kg00qf 2294 19 P3 P3 NNP cord-022526-j9kg00qf 2294 20 - - HYPH cord-022526-j9kg00qf 2294 21 3 3 CD cord-022526-j9kg00qf 2294 22 for for IN cord-022526-j9kg00qf 2294 23 a a DT cord-022526-j9kg00qf 2294 24 total total NN cord-022526-j9kg00qf 2294 25 of of IN cord-022526-j9kg00qf 2294 26 24 24 CD cord-022526-j9kg00qf 2294 27 . . . cord-022526-j9kg00qf 2295 1 The the DT cord-022526-j9kg00qf 2295 2 permanent permanent JJ cord-022526-j9kg00qf 2295 3 dental dental JJ cord-022526-j9kg00qf 2295 4 formula formula NN cord-022526-j9kg00qf 2295 5 is be VBZ cord-022526-j9kg00qf 2295 6 2 2 CD cord-022526-j9kg00qf 2295 7 times time NNS cord-022526-j9kg00qf 2295 8 I3 I3 NNP cord-022526-j9kg00qf 2295 9 - - HYPH cord-022526-j9kg00qf 2295 10 3 3 CD cord-022526-j9kg00qf 2295 11 C1 C1 NNP cord-022526-j9kg00qf 2295 12 - - HYPH cord-022526-j9kg00qf 2295 13 1 1 CD cord-022526-j9kg00qf 2295 14 P3 P3 NNP cord-022526-j9kg00qf 2295 15 - - HYPH cord-022526-j9kg00qf 2295 16 3 3 CD cord-022526-j9kg00qf 2295 17 or or CC cord-022526-j9kg00qf 2295 18 P4 P4 NNP cord-022526-j9kg00qf 2295 19 - - SYM cord-022526-j9kg00qf 2295 20 3 3 CD cord-022526-j9kg00qf 2295 21 M3 M3 NNP cord-022526-j9kg00qf 2295 22 - - HYPH cord-022526-j9kg00qf 2295 23 3 3 CD cord-022526-j9kg00qf 2295 24 for for IN cord-022526-j9kg00qf 2295 25 a a DT cord-022526-j9kg00qf 2295 26 total total NN cord-022526-j9kg00qf 2295 27 of of IN cord-022526-j9kg00qf 2295 28 40 40 CD cord-022526-j9kg00qf 2295 29 or or CC cord-022526-j9kg00qf 2295 30 42 42 CD cord-022526-j9kg00qf 2295 31 . . . cord-022526-j9kg00qf 2296 1 In in IN cord-022526-j9kg00qf 2296 2 the the DT cord-022526-j9kg00qf 2296 3 mare mare NN cord-022526-j9kg00qf 2296 4 the the DT cord-022526-j9kg00qf 2296 5 canine canine JJ cord-022526-j9kg00qf 2296 6 teeth tooth NNS cord-022526-j9kg00qf 2296 7 are be VBP cord-022526-j9kg00qf 2296 8 usually usually RB cord-022526-j9kg00qf 2296 9 small small JJ cord-022526-j9kg00qf 2296 10 or or CC cord-022526-j9kg00qf 2296 11 do do VBP cord-022526-j9kg00qf 2296 12 not not RB cord-022526-j9kg00qf 2296 13 erupt erupt VB cord-022526-j9kg00qf 2296 14 , , , cord-022526-j9kg00qf 2296 15 hence hence RB cord-022526-j9kg00qf 2296 16 reducing reduce VBG cord-022526-j9kg00qf 2296 17 the the DT cord-022526-j9kg00qf 2296 18 number number NN cord-022526-j9kg00qf 2296 19 to to IN cord-022526-j9kg00qf 2296 20 36 36 CD cord-022526-j9kg00qf 2296 21 or or CC cord-022526-j9kg00qf 2296 22 38 38 CD cord-022526-j9kg00qf 2296 23 . . . cord-022526-j9kg00qf 2297 1 The the DT cord-022526-j9kg00qf 2297 2 first first JJ cord-022526-j9kg00qf 2297 3 premolar premolar JJ cord-022526-j9kg00qf 2297 4 tooth tooth NN cord-022526-j9kg00qf 2297 5 ( ( -LRB- cord-022526-j9kg00qf 2297 6 wolf wolf NNP cord-022526-j9kg00qf 2297 7 tooth tooth NN cord-022526-j9kg00qf 2297 8 ) ) -RRB- cord-022526-j9kg00qf 2297 9 is be VBZ cord-022526-j9kg00qf 2297 10 often often RB cord-022526-j9kg00qf 2297 11 absent absent JJ cord-022526-j9kg00qf 2297 12 and and CC cord-022526-j9kg00qf 2297 13 has have VBZ cord-022526-j9kg00qf 2297 14 been be VBN cord-022526-j9kg00qf 2297 15 reported report VBN cord-022526-j9kg00qf 2297 16 as as IN cord-022526-j9kg00qf 2297 17 occurring occur VBG cord-022526-j9kg00qf 2297 18 in in IN cord-022526-j9kg00qf 2297 19 only only RB cord-022526-j9kg00qf 2297 20 20 20 CD cord-022526-j9kg00qf 2297 21 % % NN cord-022526-j9kg00qf 2297 22 of of IN cord-022526-j9kg00qf 2297 23 the the DT cord-022526-j9kg00qf 2297 24 upper upper JJ cord-022526-j9kg00qf 2297 25 dentition dentition NN cord-022526-j9kg00qf 2297 26 of of IN cord-022526-j9kg00qf 2297 27 Thoroughbred thoroughbred JJ cord-022526-j9kg00qf 2297 28 horses horse NNS cord-022526-j9kg00qf 2297 29 . . . cord-022526-j9kg00qf 2298 1 3 3 LS cord-022526-j9kg00qf 2299 1 The the DT cord-022526-j9kg00qf 2299 2 teeth tooth NNS cord-022526-j9kg00qf 2299 3 of of IN cord-022526-j9kg00qf 2299 4 the the DT cord-022526-j9kg00qf 2299 5 horse horse NN cord-022526-j9kg00qf 2299 6 are be VBP cord-022526-j9kg00qf 2299 7 complex complex JJ cord-022526-j9kg00qf 2299 8 in in IN cord-022526-j9kg00qf 2299 9 shape shape NN cord-022526-j9kg00qf 2299 10 and and CC cord-022526-j9kg00qf 2299 11 are be VBP cord-022526-j9kg00qf 2299 12 compounded compound VBN cord-022526-j9kg00qf 2299 13 of of IN cord-022526-j9kg00qf 2299 14 different different JJ cord-022526-j9kg00qf 2299 15 materials material NNS cord-022526-j9kg00qf 2299 16 ( ( -LRB- cord-022526-j9kg00qf 2299 17 dentin dentin NN cord-022526-j9kg00qf 2299 18 , , , cord-022526-j9kg00qf 2299 19 cementum cementum NN cord-022526-j9kg00qf 2299 20 , , , cord-022526-j9kg00qf 2299 21 and and CC cord-022526-j9kg00qf 2299 22 enamel enamel NN cord-022526-j9kg00qf 2299 23 ) ) -RRB- cord-022526-j9kg00qf 2299 24 . . . cord-022526-j9kg00qf 2300 1 They -PRON- PRP cord-022526-j9kg00qf 2300 2 function function VBP cord-022526-j9kg00qf 2300 3 as as IN cord-022526-j9kg00qf 2300 4 grinding grind VBG cord-022526-j9kg00qf 2300 5 blades blade NNS cord-022526-j9kg00qf 2300 6 to to TO cord-022526-j9kg00qf 2300 7 masticate masticate VB cord-022526-j9kg00qf 2300 8 and and CC cord-022526-j9kg00qf 2300 9 macerate macerate VB cord-022526-j9kg00qf 2300 10 cellulose cellulose NN cord-022526-j9kg00qf 2300 11 food food NN cord-022526-j9kg00qf 2300 12 in in IN cord-022526-j9kg00qf 2300 13 the the DT cord-022526-j9kg00qf 2300 14 important important JJ cord-022526-j9kg00qf 2300 15 first first JJ cord-022526-j9kg00qf 2300 16 stage stage NN cord-022526-j9kg00qf 2300 17 of of IN cord-022526-j9kg00qf 2300 18 the the DT cord-022526-j9kg00qf 2300 19 digestive digestive JJ cord-022526-j9kg00qf 2300 20 process process NN cord-022526-j9kg00qf 2300 21 . . . cord-022526-j9kg00qf 2301 1 The the DT cord-022526-j9kg00qf 2301 2 cheek cheek NN cord-022526-j9kg00qf 2301 3 teeth tooth NNS cord-022526-j9kg00qf 2301 4 in in IN cord-022526-j9kg00qf 2301 5 the the DT cord-022526-j9kg00qf 2301 6 horse horse NN cord-022526-j9kg00qf 2301 7 are be VBP cord-022526-j9kg00qf 2301 8 a a DT cord-022526-j9kg00qf 2301 9 well well RB cord-022526-j9kg00qf 2301 10 - - HYPH cord-022526-j9kg00qf 2301 11 documented document VBN cord-022526-j9kg00qf 2301 12 feature feature NN cord-022526-j9kg00qf 2301 13 of of IN cord-022526-j9kg00qf 2301 14 the the DT cord-022526-j9kg00qf 2301 15 evolution evolution NN cord-022526-j9kg00qf 2301 16 of of IN cord-022526-j9kg00qf 2301 17 Equus Equus NNP cord-022526-j9kg00qf 2301 18 caballus caballus NN cord-022526-j9kg00qf 2301 19 . . . cord-022526-j9kg00qf 2302 1 The the DT cord-022526-j9kg00qf 2302 2 first first JJ cord-022526-j9kg00qf 2302 3 incisor incisor NN cord-022526-j9kg00qf 2302 4 is be VBZ cord-022526-j9kg00qf 2302 5 present present JJ cord-022526-j9kg00qf 2302 6 at at IN cord-022526-j9kg00qf 2302 7 birth birth NN cord-022526-j9kg00qf 2302 8 or or CC cord-022526-j9kg00qf 2302 9 the the DT cord-022526-j9kg00qf 2302 10 first first JJ cord-022526-j9kg00qf 2302 11 week week NN cord-022526-j9kg00qf 2302 12 of of IN cord-022526-j9kg00qf 2302 13 life life NN cord-022526-j9kg00qf 2302 14 . . . cord-022526-j9kg00qf 2303 1 The the DT cord-022526-j9kg00qf 2303 2 second second JJ cord-022526-j9kg00qf 2303 3 incisor incisor NN cord-022526-j9kg00qf 2303 4 erupts erupt VBZ cord-022526-j9kg00qf 2303 5 at at IN cord-022526-j9kg00qf 2303 6 4 4 CD cord-022526-j9kg00qf 2303 7 to to TO cord-022526-j9kg00qf 2303 8 6 6 CD cord-022526-j9kg00qf 2303 9 weeks week NNS cord-022526-j9kg00qf 2303 10 of of IN cord-022526-j9kg00qf 2303 11 age age NN cord-022526-j9kg00qf 2303 12 ; ; : cord-022526-j9kg00qf 2303 13 the the DT cord-022526-j9kg00qf 2303 14 third third JJ cord-022526-j9kg00qf 2303 15 incisor incisor NN cord-022526-j9kg00qf 2303 16 , , , cord-022526-j9kg00qf 2303 17 at at IN cord-022526-j9kg00qf 2303 18 6 6 CD cord-022526-j9kg00qf 2303 19 to to TO cord-022526-j9kg00qf 2303 20 9 9 CD cord-022526-j9kg00qf 2303 21 months month NNS cord-022526-j9kg00qf 2303 22 of of IN cord-022526-j9kg00qf 2303 23 age age NN cord-022526-j9kg00qf 2303 24 ; ; : cord-022526-j9kg00qf 2303 25 the the DT cord-022526-j9kg00qf 2303 26 first first JJ cord-022526-j9kg00qf 2303 27 and and CC cord-022526-j9kg00qf 2303 28 second second JJ cord-022526-j9kg00qf 2303 29 premolars premolar NNS cord-022526-j9kg00qf 2303 30 , , , cord-022526-j9kg00qf 2303 31 at at IN cord-022526-j9kg00qf 2303 32 birth birth NN cord-022526-j9kg00qf 2303 33 to to IN cord-022526-j9kg00qf 2303 34 2 2 CD cord-022526-j9kg00qf 2303 35 weeks week NNS cord-022526-j9kg00qf 2303 36 of of IN cord-022526-j9kg00qf 2303 37 age age NN cord-022526-j9kg00qf 2303 38 ; ; : cord-022526-j9kg00qf 2303 39 and and CC cord-022526-j9kg00qf 2303 40 the the DT cord-022526-j9kg00qf 2303 41 third third JJ cord-022526-j9kg00qf 2303 42 premolar premolar JJ cord-022526-j9kg00qf 2303 43 , , , cord-022526-j9kg00qf 2303 44 3 3 CD cord-022526-j9kg00qf 2303 45 months month NNS cord-022526-j9kg00qf 2303 46 of of IN cord-022526-j9kg00qf 2303 47 age age NN cord-022526-j9kg00qf 2303 48 . . . cord-022526-j9kg00qf 2304 1 The the DT cord-022526-j9kg00qf 2304 2 eruption eruption NN cord-022526-j9kg00qf 2304 3 times time VBZ cord-022526-j9kg00qf 2304 4 for for IN cord-022526-j9kg00qf 2304 5 the the DT cord-022526-j9kg00qf 2304 6 permanent permanent JJ cord-022526-j9kg00qf 2304 7 teeth tooth NNS cord-022526-j9kg00qf 2304 8 are be VBP cord-022526-j9kg00qf 2304 9 as as IN cord-022526-j9kg00qf 2304 10 follows follow VBZ cord-022526-j9kg00qf 2304 11 : : : cord-022526-j9kg00qf 2304 12 first first JJ cord-022526-j9kg00qf 2304 13 incisor incisor NN cord-022526-j9kg00qf 2304 14 , , , cord-022526-j9kg00qf 2304 15 2 2 CD cord-022526-j9kg00qf 2304 16 1 1 CD cord-022526-j9kg00qf 2304 17 / / SYM cord-022526-j9kg00qf 2304 18 2 2 CD cord-022526-j9kg00qf 2304 19 years year NNS cord-022526-j9kg00qf 2304 20 of of IN cord-022526-j9kg00qf 2304 21 age age NN cord-022526-j9kg00qf 2304 22 ; ; , cord-022526-j9kg00qf 2304 23 second second JJ cord-022526-j9kg00qf 2304 24 incisor incisor NN cord-022526-j9kg00qf 2304 25 , , , cord-022526-j9kg00qf 2304 26 3 3 CD cord-022526-j9kg00qf 2304 27 1 1 CD cord-022526-j9kg00qf 2304 28 / / SYM cord-022526-j9kg00qf 2304 29 2 2 CD cord-022526-j9kg00qf 2304 30 years year NNS cord-022526-j9kg00qf 2304 31 of of IN cord-022526-j9kg00qf 2304 32 age age NN cord-022526-j9kg00qf 2304 33 ; ; , cord-022526-j9kg00qf 2304 34 third third JJ cord-022526-j9kg00qf 2304 35 incisor incisor NN cord-022526-j9kg00qf 2304 36 , , , cord-022526-j9kg00qf 2304 37 4 4 CD cord-022526-j9kg00qf 2304 38 1 1 CD cord-022526-j9kg00qf 2304 39 / / SYM cord-022526-j9kg00qf 2304 40 2 2 CD cord-022526-j9kg00qf 2304 41 years year NNS cord-022526-j9kg00qf 2304 42 of of IN cord-022526-j9kg00qf 2304 43 age age NN cord-022526-j9kg00qf 2304 44 ; ; : cord-022526-j9kg00qf 2304 45 the the DT cord-022526-j9kg00qf 2304 46 canine canine JJ cord-022526-j9kg00qf 2304 47 tooth tooth NN cord-022526-j9kg00qf 2304 48 , , , cord-022526-j9kg00qf 2304 49 4 4 CD cord-022526-j9kg00qf 2304 50 to to TO cord-022526-j9kg00qf 2304 51 5 5 CD cord-022526-j9kg00qf 2304 52 years year NNS cord-022526-j9kg00qf 2304 53 of of IN cord-022526-j9kg00qf 2304 54 age age NN cord-022526-j9kg00qf 2304 55 ; ; : cord-022526-j9kg00qf 2304 56 the the DT cord-022526-j9kg00qf 2304 57 first first JJ cord-022526-j9kg00qf 2304 58 premolar premolar JJ cord-022526-j9kg00qf 2304 59 ( ( -LRB- cord-022526-j9kg00qf 2304 60 wolf wolf NNP cord-022526-j9kg00qf 2304 61 tooth tooth NN cord-022526-j9kg00qf 2304 62 ) ) -RRB- cord-022526-j9kg00qf 2304 63 , , , cord-022526-j9kg00qf 2304 64 5 5 CD cord-022526-j9kg00qf 2304 65 to to TO cord-022526-j9kg00qf 2304 66 6 6 CD cord-022526-j9kg00qf 2304 67 months month NNS cord-022526-j9kg00qf 2304 68 of of IN cord-022526-j9kg00qf 2304 69 age age NN cord-022526-j9kg00qf 2304 70 ; ; : cord-022526-j9kg00qf 2304 71 the the DT cord-022526-j9kg00qf 2304 72 second second JJ cord-022526-j9kg00qf 2304 73 premolar premolar JJ cord-022526-j9kg00qf 2304 74 , , , cord-022526-j9kg00qf 2304 75 2 2 CD cord-022526-j9kg00qf 2304 76 1 1 CD cord-022526-j9kg00qf 2304 77 / / SYM cord-022526-j9kg00qf 2304 78 2 2 CD cord-022526-j9kg00qf 2304 79 years year NNS cord-022526-j9kg00qf 2304 80 of of IN cord-022526-j9kg00qf 2304 81 age age NN cord-022526-j9kg00qf 2304 82 ; ; : cord-022526-j9kg00qf 2304 83 the the DT cord-022526-j9kg00qf 2304 84 third third JJ cord-022526-j9kg00qf 2304 85 premolar premolar JJ cord-022526-j9kg00qf 2304 86 , , , cord-022526-j9kg00qf 2304 87 3 3 CD cord-022526-j9kg00qf 2304 88 years year NNS cord-022526-j9kg00qf 2304 89 of of IN cord-022526-j9kg00qf 2304 90 age age NN cord-022526-j9kg00qf 2304 91 ; ; : cord-022526-j9kg00qf 2304 92 the the DT cord-022526-j9kg00qf 2304 93 fourth fourth JJ cord-022526-j9kg00qf 2304 94 premolar premolar JJ cord-022526-j9kg00qf 2304 95 , , , cord-022526-j9kg00qf 2304 96 4 4 CD cord-022526-j9kg00qf 2304 97 years year NNS cord-022526-j9kg00qf 2304 98 of of IN cord-022526-j9kg00qf 2304 99 age age NN cord-022526-j9kg00qf 2304 100 ; ; : cord-022526-j9kg00qf 2304 101 the the DT cord-022526-j9kg00qf 2304 102 first first JJ cord-022526-j9kg00qf 2304 103 molar molar NN cord-022526-j9kg00qf 2304 104 , , , cord-022526-j9kg00qf 2304 105 10 10 CD cord-022526-j9kg00qf 2304 106 to to TO cord-022526-j9kg00qf 2304 107 12 12 CD cord-022526-j9kg00qf 2304 108 months month NNS cord-022526-j9kg00qf 2304 109 of of IN cord-022526-j9kg00qf 2304 110 age age NN cord-022526-j9kg00qf 2304 111 ; ; : cord-022526-j9kg00qf 2304 112 the the DT cord-022526-j9kg00qf 2304 113 second second JJ cord-022526-j9kg00qf 2304 114 molar molar NN cord-022526-j9kg00qf 2304 115 , , , cord-022526-j9kg00qf 2304 116 2 2 CD cord-022526-j9kg00qf 2304 117 years year NNS cord-022526-j9kg00qf 2304 118 of of IN cord-022526-j9kg00qf 2304 119 age age NN cord-022526-j9kg00qf 2304 120 ; ; : cord-022526-j9kg00qf 2304 121 and and CC cord-022526-j9kg00qf 2304 122 the the DT cord-022526-j9kg00qf 2304 123 third third JJ cord-022526-j9kg00qf 2304 124 molar molar NN cord-022526-j9kg00qf 2304 125 , , , cord-022526-j9kg00qf 2304 126 3 3 CD cord-022526-j9kg00qf 2304 127 1 1 CD cord-022526-j9kg00qf 2304 128 / / SYM cord-022526-j9kg00qf 2304 129 2 2 CD cord-022526-j9kg00qf 2304 130 to to IN cord-022526-j9kg00qf 2304 131 4 4 CD cord-022526-j9kg00qf 2304 132 years year NNS cord-022526-j9kg00qf 2304 133 of of IN cord-022526-j9kg00qf 2304 134 age age NN cord-022526-j9kg00qf 2304 135 . . . cord-022526-j9kg00qf 2305 1 This this DT cord-022526-j9kg00qf 2305 2 eruption eruption NN cord-022526-j9kg00qf 2305 3 sequence sequence NN cord-022526-j9kg00qf 2305 4 clearly clearly RB cord-022526-j9kg00qf 2305 5 indicates indicate VBZ cord-022526-j9kg00qf 2305 6 that that IN cord-022526-j9kg00qf 2305 7 the the DT cord-022526-j9kg00qf 2305 8 eruption eruption NN cord-022526-j9kg00qf 2305 9 of of IN cord-022526-j9kg00qf 2305 10 the the DT cord-022526-j9kg00qf 2305 11 second second JJ cord-022526-j9kg00qf 2305 12 and and CC cord-022526-j9kg00qf 2305 13 third third JJ cord-022526-j9kg00qf 2305 14 permanent permanent JJ cord-022526-j9kg00qf 2305 15 premolar premolar JJ cord-022526-j9kg00qf 2305 16 teeth tooth NNS cord-022526-j9kg00qf 2305 17 give give VBP cord-022526-j9kg00qf 2305 18 the the DT cord-022526-j9kg00qf 2305 19 potential potential NN cord-022526-j9kg00qf 2305 20 for for IN cord-022526-j9kg00qf 2305 21 dental dental JJ cord-022526-j9kg00qf 2305 22 impaction impaction NN cord-022526-j9kg00qf 2305 23 . . . cord-022526-j9kg00qf 2306 1 The the DT cord-022526-j9kg00qf 2306 2 modern modern JJ cord-022526-j9kg00qf 2306 3 horse horse NN cord-022526-j9kg00qf 2306 4 has have VBZ cord-022526-j9kg00qf 2306 5 six six CD cord-022526-j9kg00qf 2306 6 incisor incisor NN cord-022526-j9kg00qf 2306 7 teeth tooth NNS cord-022526-j9kg00qf 2306 8 in in IN cord-022526-j9kg00qf 2306 9 each each DT cord-022526-j9kg00qf 2306 10 jaw jaw NN cord-022526-j9kg00qf 2306 11 that that WDT cord-022526-j9kg00qf 2306 12 are be VBP cord-022526-j9kg00qf 2306 13 placed place VBN cord-022526-j9kg00qf 2306 14 close close RB cord-022526-j9kg00qf 2306 15 together together RB cord-022526-j9kg00qf 2306 16 so so IN cord-022526-j9kg00qf 2306 17 that that IN cord-022526-j9kg00qf 2306 18 the the DT cord-022526-j9kg00qf 2306 19 labile labile JJ cord-022526-j9kg00qf 2306 20 edges edge NNS cord-022526-j9kg00qf 2306 21 form form VBP cord-022526-j9kg00qf 2306 22 a a DT cord-022526-j9kg00qf 2306 23 semicircle semicircle NN cord-022526-j9kg00qf 2306 24 . . . cord-022526-j9kg00qf 2307 1 The the DT cord-022526-j9kg00qf 2307 2 occlusal occlusal NN cord-022526-j9kg00qf 2307 3 surface surface NN cord-022526-j9kg00qf 2307 4 has have VBZ cord-022526-j9kg00qf 2307 5 a a DT cord-022526-j9kg00qf 2307 6 deep deep JJ cord-022526-j9kg00qf 2307 7 enamel enamel NN cord-022526-j9kg00qf 2307 8 invagination invagination NN cord-022526-j9kg00qf 2307 9 ( ( -LRB- cord-022526-j9kg00qf 2307 10 infundibulum infundibulum NNP cord-022526-j9kg00qf 2307 11 ) ) -RRB- cord-022526-j9kg00qf 2307 12 that that WDT cord-022526-j9kg00qf 2307 13 is be VBZ cord-022526-j9kg00qf 2307 14 filled fill VBN cord-022526-j9kg00qf 2307 15 only only RB cord-022526-j9kg00qf 2307 16 partially partially RB cord-022526-j9kg00qf 2307 17 with with IN cord-022526-j9kg00qf 2307 18 cementum cementum NN cord-022526-j9kg00qf 2307 19 . . . cord-022526-j9kg00qf 2308 1 As as IN cord-022526-j9kg00qf 2308 2 the the DT cord-022526-j9kg00qf 2308 3 incisor incisor NN cord-022526-j9kg00qf 2308 4 teeth tooth NNS cord-022526-j9kg00qf 2308 5 wear wear VBP cord-022526-j9kg00qf 2308 6 , , , cord-022526-j9kg00qf 2308 7 a a DT cord-022526-j9kg00qf 2308 8 characteristic characteristic JJ cord-022526-j9kg00qf 2308 9 pattern pattern NN cord-022526-j9kg00qf 2308 10 forms form NNS cord-022526-j9kg00qf 2308 11 in in IN cord-022526-j9kg00qf 2308 12 which which WDT cord-022526-j9kg00qf 2308 13 the the DT cord-022526-j9kg00qf 2308 14 infundibulum infundibulum NN cord-022526-j9kg00qf 2308 15 is be VBZ cord-022526-j9kg00qf 2308 16 surrounded surround VBN cord-022526-j9kg00qf 2308 17 by by IN cord-022526-j9kg00qf 2308 18 rings ring NNS cord-022526-j9kg00qf 2308 19 of of IN cord-022526-j9kg00qf 2308 20 enamel enamel NN cord-022526-j9kg00qf 2308 21 , , , cord-022526-j9kg00qf 2308 22 dentin dentin NN cord-022526-j9kg00qf 2308 23 , , , cord-022526-j9kg00qf 2308 24 enamel enamel NN cord-022526-j9kg00qf 2308 25 , , , cord-022526-j9kg00qf 2308 26 and and CC cord-022526-j9kg00qf 2308 27 crown crown NN cord-022526-j9kg00qf 2308 28 cementum cementum NN cord-022526-j9kg00qf 2308 29 in in IN cord-022526-j9kg00qf 2308 30 a a DT cord-022526-j9kg00qf 2308 31 concentric concentric JJ cord-022526-j9kg00qf 2308 32 pattern pattern NN cord-022526-j9kg00qf 2308 33 . . . cord-022526-j9kg00qf 2309 1 Each each DT cord-022526-j9kg00qf 2309 2 incisor incisor NN cord-022526-j9kg00qf 2309 3 tooth tooth NN cord-022526-j9kg00qf 2309 4 tapers taper VBZ cord-022526-j9kg00qf 2309 5 from from IN cord-022526-j9kg00qf 2309 6 a a DT cord-022526-j9kg00qf 2309 7 broad broad JJ cord-022526-j9kg00qf 2309 8 crown crown NN cord-022526-j9kg00qf 2309 9 to to IN cord-022526-j9kg00qf 2309 10 a a DT cord-022526-j9kg00qf 2309 11 narrow narrow JJ cord-022526-j9kg00qf 2309 12 root root NN cord-022526-j9kg00qf 2309 13 so so IN cord-022526-j9kg00qf 2309 14 that that IN cord-022526-j9kg00qf 2309 15 as as IN cord-022526-j9kg00qf 2309 16 the the DT cord-022526-j9kg00qf 2309 17 midportion midportion NN cord-022526-j9kg00qf 2309 18 of of IN cord-022526-j9kg00qf 2309 19 the the DT cord-022526-j9kg00qf 2309 20 incisor incisor NN cord-022526-j9kg00qf 2309 21 is be VBZ cord-022526-j9kg00qf 2309 22 exposed expose VBN cord-022526-j9kg00qf 2309 23 to to TO cord-022526-j9kg00qf 2309 24 wear wear VB cord-022526-j9kg00qf 2309 25 , , , cord-022526-j9kg00qf 2309 26 the the DT cord-022526-j9kg00qf 2309 27 cross cross JJ cord-022526-j9kg00qf 2309 28 - - JJ cord-022526-j9kg00qf 2309 29 sectional sectional JJ cord-022526-j9kg00qf 2309 30 diameters diameter NNS cord-022526-j9kg00qf 2309 31 are be VBP cord-022526-j9kg00qf 2309 32 about about RB cord-022526-j9kg00qf 2309 33 equal equal JJ cord-022526-j9kg00qf 2309 34 ; ; : cord-022526-j9kg00qf 2309 35 that that RB cord-022526-j9kg00qf 2309 36 is is RB cord-022526-j9kg00qf 2309 37 , , , cord-022526-j9kg00qf 2309 38 at at IN cord-022526-j9kg00qf 2309 39 14 14 CD cord-022526-j9kg00qf 2309 40 years year NNS cord-022526-j9kg00qf 2309 41 of of IN cord-022526-j9kg00qf 2309 42 age age NN cord-022526-j9kg00qf 2309 43 , , , cord-022526-j9kg00qf 2309 44 the the DT cord-022526-j9kg00qf 2309 45 central central JJ cord-022526-j9kg00qf 2309 46 incisor incisor NN cord-022526-j9kg00qf 2309 47 tooth tooth NN cord-022526-j9kg00qf 2309 48 of of IN cord-022526-j9kg00qf 2309 49 the the DT cord-022526-j9kg00qf 2309 50 horse horse NN cord-022526-j9kg00qf 2309 51 has have VBZ cord-022526-j9kg00qf 2309 52 an an DT cord-022526-j9kg00qf 2309 53 occlusal occlusal NN cord-022526-j9kg00qf 2309 54 surface surface NN cord-022526-j9kg00qf 2309 55 that that WDT cord-022526-j9kg00qf 2309 56 is be VBZ cord-022526-j9kg00qf 2309 57 an an DT cord-022526-j9kg00qf 2309 58 equilateral equilateral JJ cord-022526-j9kg00qf 2309 59 triangle triangle NN cord-022526-j9kg00qf 2309 60 . . . cord-022526-j9kg00qf 2310 1 Observations observation NNS cord-022526-j9kg00qf 2310 2 on on IN cord-022526-j9kg00qf 2310 3 the the DT cord-022526-j9kg00qf 2310 4 state state NN cord-022526-j9kg00qf 2310 5 of of IN cord-022526-j9kg00qf 2310 6 eruption eruption NN cord-022526-j9kg00qf 2310 7 , , , cord-022526-j9kg00qf 2310 8 the the DT cord-022526-j9kg00qf 2310 9 angles angle NNS cord-022526-j9kg00qf 2310 10 of of IN cord-022526-j9kg00qf 2310 11 incidence incidence NN cord-022526-j9kg00qf 2310 12 of of IN cord-022526-j9kg00qf 2310 13 the the DT cord-022526-j9kg00qf 2310 14 incisor incisor NN cord-022526-j9kg00qf 2310 15 teeth tooth NNS cord-022526-j9kg00qf 2310 16 , , , cord-022526-j9kg00qf 2310 17 and and CC cord-022526-j9kg00qf 2310 18 the the DT cord-022526-j9kg00qf 2310 19 pattern pattern NN cord-022526-j9kg00qf 2310 20 of of IN cord-022526-j9kg00qf 2310 21 the the DT cord-022526-j9kg00qf 2310 22 occlusal occlusal NN cord-022526-j9kg00qf 2310 23 surfaces surface NNS cord-022526-j9kg00qf 2310 24 are be VBP cord-022526-j9kg00qf 2310 25 used use VBN cord-022526-j9kg00qf 2310 26 as as IN cord-022526-j9kg00qf 2310 27 guides guide NNS cord-022526-j9kg00qf 2310 28 for for IN cord-022526-j9kg00qf 2310 29 aging age VBG cord-022526-j9kg00qf 2310 30 of of IN cord-022526-j9kg00qf 2310 31 horses horse NNS cord-022526-j9kg00qf 2310 32 . . . cord-022526-j9kg00qf 2311 1 The the DT cord-022526-j9kg00qf 2311 2 canine canine JJ cord-022526-j9kg00qf 2311 3 teeth tooth NNS cord-022526-j9kg00qf 2311 4 are be VBP cord-022526-j9kg00qf 2311 5 simple simple JJ cord-022526-j9kg00qf 2311 6 teeth tooth NNS cord-022526-j9kg00qf 2311 7 without without IN cord-022526-j9kg00qf 2311 8 complex complex JJ cord-022526-j9kg00qf 2311 9 crowns crown NNS cord-022526-j9kg00qf 2311 10 and and CC cord-022526-j9kg00qf 2311 11 are be VBP cord-022526-j9kg00qf 2311 12 curved curved JJ cord-022526-j9kg00qf 2311 13 . . . cord-022526-j9kg00qf 2312 1 The the DT cord-022526-j9kg00qf 2312 2 crown crown NN cord-022526-j9kg00qf 2312 3 is be VBZ cord-022526-j9kg00qf 2312 4 compressed compress VBN cord-022526-j9kg00qf 2312 5 and and CC cord-022526-j9kg00qf 2312 6 is be VBZ cord-022526-j9kg00qf 2312 7 smooth smooth JJ cord-022526-j9kg00qf 2312 8 on on IN cord-022526-j9kg00qf 2312 9 its -PRON- PRP$ cord-022526-j9kg00qf 2312 10 labial labial JJ cord-022526-j9kg00qf 2312 11 aspect aspect NN cord-022526-j9kg00qf 2312 12 but but CC cord-022526-j9kg00qf 2312 13 carries carry VBZ cord-022526-j9kg00qf 2312 14 two two CD cord-022526-j9kg00qf 2312 15 ridges ridge NNS cord-022526-j9kg00qf 2312 16 on on IN cord-022526-j9kg00qf 2312 17 its -PRON- PRP$ cord-022526-j9kg00qf 2312 18 lingual lingual JJ cord-022526-j9kg00qf 2312 19 aspect aspect NN cord-022526-j9kg00qf 2312 20 . . . cord-022526-j9kg00qf 2313 1 No no DT cord-022526-j9kg00qf 2313 2 occlusal occlusal NN cord-022526-j9kg00qf 2313 3 contact contact NN cord-022526-j9kg00qf 2313 4 occurs occur VBZ cord-022526-j9kg00qf 2313 5 between between IN cord-022526-j9kg00qf 2313 6 the the DT cord-022526-j9kg00qf 2313 7 upper upper JJ cord-022526-j9kg00qf 2313 8 and and CC cord-022526-j9kg00qf 2313 9 lower low JJR cord-022526-j9kg00qf 2313 10 canine canine JJ cord-022526-j9kg00qf 2313 11 teeth tooth NNS cord-022526-j9kg00qf 2313 12 . . . cord-022526-j9kg00qf 2314 1 When when WRB cord-022526-j9kg00qf 2314 2 erupted erupt VBN cord-022526-j9kg00qf 2314 3 , , , cord-022526-j9kg00qf 2314 4 the the DT cord-022526-j9kg00qf 2314 5 six six CD cord-022526-j9kg00qf 2314 6 cheek cheek NN cord-022526-j9kg00qf 2314 7 teeth tooth NNS cord-022526-j9kg00qf 2314 8 of of IN cord-022526-j9kg00qf 2314 9 the the DT cord-022526-j9kg00qf 2314 10 horse horse NN cord-022526-j9kg00qf 2314 11 function function NN cord-022526-j9kg00qf 2314 12 as as IN cord-022526-j9kg00qf 2314 13 a a DT cord-022526-j9kg00qf 2314 14 single single JJ cord-022526-j9kg00qf 2314 15 unit unit NN cord-022526-j9kg00qf 2314 16 in in IN cord-022526-j9kg00qf 2314 17 the the DT cord-022526-j9kg00qf 2314 18 mastication mastication NN cord-022526-j9kg00qf 2314 19 of of IN cord-022526-j9kg00qf 2314 20 food food NN cord-022526-j9kg00qf 2314 21 . . . cord-022526-j9kg00qf 2315 1 Each each DT cord-022526-j9kg00qf 2315 2 arcade arcade NN cord-022526-j9kg00qf 2315 3 consists consist VBZ cord-022526-j9kg00qf 2315 4 of of IN cord-022526-j9kg00qf 2315 5 three three CD cord-022526-j9kg00qf 2315 6 premolar premolar JJ cord-022526-j9kg00qf 2315 7 and and CC cord-022526-j9kg00qf 2315 8 three three CD cord-022526-j9kg00qf 2315 9 molar molar JJ cord-022526-j9kg00qf 2315 10 teeth tooth NNS cord-022526-j9kg00qf 2315 11 . . . cord-022526-j9kg00qf 2316 1 The the DT cord-022526-j9kg00qf 2316 2 maxillary maxillary JJ cord-022526-j9kg00qf 2316 3 arcade arcade NN cord-022526-j9kg00qf 2316 4 is be VBZ cord-022526-j9kg00qf 2316 5 slightly slightly RB cord-022526-j9kg00qf 2316 6 curved curved JJ cord-022526-j9kg00qf 2316 7 , , , cord-022526-j9kg00qf 2316 8 and and CC cord-022526-j9kg00qf 2316 9 the the DT cord-022526-j9kg00qf 2316 10 teeth tooth NNS cord-022526-j9kg00qf 2316 11 have have VBP cord-022526-j9kg00qf 2316 12 a a DT cord-022526-j9kg00qf 2316 13 square square JJ cord-022526-j9kg00qf 2316 14 occlusal occlusal NN cord-022526-j9kg00qf 2316 15 surface surface NN cord-022526-j9kg00qf 2316 16 . . . cord-022526-j9kg00qf 2317 1 The the DT cord-022526-j9kg00qf 2317 2 occlusal occlusal NN cord-022526-j9kg00qf 2317 3 surfaces surface NNS cord-022526-j9kg00qf 2317 4 of of IN cord-022526-j9kg00qf 2317 5 the the DT cord-022526-j9kg00qf 2317 6 mandibular mandibular JJ cord-022526-j9kg00qf 2317 7 teeth tooth NNS cord-022526-j9kg00qf 2317 8 are be VBP cord-022526-j9kg00qf 2317 9 more more RBR cord-022526-j9kg00qf 2317 10 oblong oblong JJ cord-022526-j9kg00qf 2317 11 , , , cord-022526-j9kg00qf 2317 12 and and CC cord-022526-j9kg00qf 2317 13 each each DT cord-022526-j9kg00qf 2317 14 arcade arcade NN cord-022526-j9kg00qf 2317 15 is be VBZ cord-022526-j9kg00qf 2317 16 straighter straight JJR cord-022526-j9kg00qf 2317 17 . . . cord-022526-j9kg00qf 2318 1 The the DT cord-022526-j9kg00qf 2318 2 horse horse NN cord-022526-j9kg00qf 2318 3 is be VBZ cord-022526-j9kg00qf 2318 4 anisognathic anisognathic JJ cord-022526-j9kg00qf 2318 5 , , , cord-022526-j9kg00qf 2318 6 that that RB cord-022526-j9kg00qf 2318 7 is is RB cord-022526-j9kg00qf 2318 8 , , , cord-022526-j9kg00qf 2318 9 the the DT cord-022526-j9kg00qf 2318 10 distance distance NN cord-022526-j9kg00qf 2318 11 between between IN cord-022526-j9kg00qf 2318 12 the the DT cord-022526-j9kg00qf 2318 13 mandibular mandibular JJ cord-022526-j9kg00qf 2318 14 teeth tooth NNS cord-022526-j9kg00qf 2318 15 is be VBZ cord-022526-j9kg00qf 2318 16 narrower narrow JJR cord-022526-j9kg00qf 2318 17 ( ( -LRB- cord-022526-j9kg00qf 2318 18 one one CD cord-022526-j9kg00qf 2318 19 - - HYPH cord-022526-j9kg00qf 2318 20 third third NN cord-022526-j9kg00qf 2318 21 ) ) -RRB- cord-022526-j9kg00qf 2318 22 than than IN cord-022526-j9kg00qf 2318 23 the the DT cord-022526-j9kg00qf 2318 24 distance distance NN cord-022526-j9kg00qf 2318 25 between between IN cord-022526-j9kg00qf 2318 26 the the DT cord-022526-j9kg00qf 2318 27 upper upper JJ cord-022526-j9kg00qf 2318 28 cheek cheek NN cord-022526-j9kg00qf 2318 29 teeth tooth NNS cord-022526-j9kg00qf 2318 30 . . . cord-022526-j9kg00qf 2319 1 This this DT cord-022526-j9kg00qf 2319 2 anatomic anatomic JJ cord-022526-j9kg00qf 2319 3 arrangement arrangement NN cord-022526-j9kg00qf 2319 4 affects affect VBZ cord-022526-j9kg00qf 2319 5 the the DT cord-022526-j9kg00qf 2319 6 inclination inclination NN cord-022526-j9kg00qf 2319 7 of of IN cord-022526-j9kg00qf 2319 8 the the DT cord-022526-j9kg00qf 2319 9 dental dental JJ cord-022526-j9kg00qf 2319 10 arcade arcade NN cord-022526-j9kg00qf 2319 11 as as IN cord-022526-j9kg00qf 2319 12 the the DT cord-022526-j9kg00qf 2319 13 jaws jaw NNS cord-022526-j9kg00qf 2319 14 slide slide VBP cord-022526-j9kg00qf 2319 15 across across IN cord-022526-j9kg00qf 2319 16 each each DT cord-022526-j9kg00qf 2319 17 other other JJ cord-022526-j9kg00qf 2319 18 in in IN cord-022526-j9kg00qf 2319 19 the the DT cord-022526-j9kg00qf 2319 20 food food NN cord-022526-j9kg00qf 2319 21 preparation preparation NN cord-022526-j9kg00qf 2319 22 process process NN cord-022526-j9kg00qf 2319 23 . . . cord-022526-j9kg00qf 2320 1 The the DT cord-022526-j9kg00qf 2320 2 unworn unworn JJ cord-022526-j9kg00qf 2320 3 upper upper JJ cord-022526-j9kg00qf 2320 4 cheek cheek NN cord-022526-j9kg00qf 2320 5 tooth tooth NN cord-022526-j9kg00qf 2320 6 presents present VBZ cord-022526-j9kg00qf 2320 7 a a DT cord-022526-j9kg00qf 2320 8 surface surface NN cord-022526-j9kg00qf 2320 9 with with IN cord-022526-j9kg00qf 2320 10 two two CD cord-022526-j9kg00qf 2320 11 undulating undulating JJ cord-022526-j9kg00qf 2320 12 and and CC cord-022526-j9kg00qf 2320 13 narrow narrow JJ cord-022526-j9kg00qf 2320 14 ridges ridge NNS cord-022526-j9kg00qf 2320 15 , , , cord-022526-j9kg00qf 2320 16 one one CD cord-022526-j9kg00qf 2320 17 of of IN cord-022526-j9kg00qf 2320 18 which which WDT cord-022526-j9kg00qf 2320 19 is be VBZ cord-022526-j9kg00qf 2320 20 lateral lateral JJ cord-022526-j9kg00qf 2320 21 and and CC cord-022526-j9kg00qf 2320 22 the the DT cord-022526-j9kg00qf 2320 23 other other JJ cord-022526-j9kg00qf 2320 24 medial medial NN cord-022526-j9kg00qf 2320 25 . . . cord-022526-j9kg00qf 2321 1 On on IN cord-022526-j9kg00qf 2321 2 the the DT cord-022526-j9kg00qf 2321 3 rostral rostral JJ cord-022526-j9kg00qf 2321 4 and and CC cord-022526-j9kg00qf 2321 5 lingual lingual JJ cord-022526-j9kg00qf 2321 6 side side NN cord-022526-j9kg00qf 2321 7 of of IN cord-022526-j9kg00qf 2321 8 the the DT cord-022526-j9kg00qf 2321 9 medial medial JJ cord-022526-j9kg00qf 2321 10 style style NN cord-022526-j9kg00qf 2321 11 is be VBZ cord-022526-j9kg00qf 2321 12 an an DT cord-022526-j9kg00qf 2321 13 extra extra JJ cord-022526-j9kg00qf 2321 14 hillock hillock NN cord-022526-j9kg00qf 2321 15 . . . cord-022526-j9kg00qf 2322 1 The the DT cord-022526-j9kg00qf 2322 2 central central JJ cord-022526-j9kg00qf 2322 3 portion portion NN cord-022526-j9kg00qf 2322 4 of of IN cord-022526-j9kg00qf 2322 5 these these DT cord-022526-j9kg00qf 2322 6 surfaces surface NNS cord-022526-j9kg00qf 2322 7 is be VBZ cord-022526-j9kg00qf 2322 8 indented indent VBN cord-022526-j9kg00qf 2322 9 by by IN cord-022526-j9kg00qf 2322 10 two two CD cord-022526-j9kg00qf 2322 11 depressions depression NNS cord-022526-j9kg00qf 2322 12 that that WDT cord-022526-j9kg00qf 2322 13 are be VBP cord-022526-j9kg00qf 2322 14 comparable comparable JJ cord-022526-j9kg00qf 2322 15 with with IN cord-022526-j9kg00qf 2322 16 , , , cord-022526-j9kg00qf 2322 17 but but CC cord-022526-j9kg00qf 2322 18 much much RB cord-022526-j9kg00qf 2322 19 deeper deep JJR cord-022526-j9kg00qf 2322 20 than than IN cord-022526-j9kg00qf 2322 21 , , , cord-022526-j9kg00qf 2322 22 the the DT cord-022526-j9kg00qf 2322 23 infundibula infundibula NN cord-022526-j9kg00qf 2322 24 of of IN cord-022526-j9kg00qf 2322 25 the the DT cord-022526-j9kg00qf 2322 26 incisor incisor NN cord-022526-j9kg00qf 2322 27 teeth tooth NNS cord-022526-j9kg00qf 2322 28 . . . cord-022526-j9kg00qf 2323 1 When when WRB cord-022526-j9kg00qf 2323 2 the the DT cord-022526-j9kg00qf 2323 3 teeth tooth NNS cord-022526-j9kg00qf 2323 4 have have VBP cord-022526-j9kg00qf 2323 5 been be VBN cord-022526-j9kg00qf 2323 6 subjected subject VBN cord-022526-j9kg00qf 2323 7 to to TO cord-022526-j9kg00qf 2323 8 wear wear VB cord-022526-j9kg00qf 2323 9 , , , cord-022526-j9kg00qf 2323 10 the the DT cord-022526-j9kg00qf 2323 11 enamel enamel NN cord-022526-j9kg00qf 2323 12 that that WDT cord-022526-j9kg00qf 2323 13 closed close VBD cord-022526-j9kg00qf 2323 14 the the DT cord-022526-j9kg00qf 2323 15 ridges ridge NNS cord-022526-j9kg00qf 2323 16 is be VBZ cord-022526-j9kg00qf 2323 17 worn wear VBN cord-022526-j9kg00qf 2323 18 through through IN cord-022526-j9kg00qf 2323 19 and and CC cord-022526-j9kg00qf 2323 20 the the DT cord-022526-j9kg00qf 2323 21 underlying underlie VBG cord-022526-j9kg00qf 2323 22 dentin dentin NN cord-022526-j9kg00qf 2323 23 appears appear VBZ cord-022526-j9kg00qf 2323 24 on on IN cord-022526-j9kg00qf 2323 25 the the DT cord-022526-j9kg00qf 2323 26 surface surface NN cord-022526-j9kg00qf 2323 27 . . . cord-022526-j9kg00qf 2324 1 Thus thus RB cord-022526-j9kg00qf 2324 2 after after IN cord-022526-j9kg00qf 2324 3 a a DT cord-022526-j9kg00qf 2324 4 time time NN cord-022526-j9kg00qf 2324 5 the the DT cord-022526-j9kg00qf 2324 6 chewing chewing NN cord-022526-j9kg00qf 2324 7 surface surface NN cord-022526-j9kg00qf 2324 8 displays display VBZ cord-022526-j9kg00qf 2324 9 a a DT cord-022526-j9kg00qf 2324 10 complicated complicated JJ cord-022526-j9kg00qf 2324 11 pattern pattern NN cord-022526-j9kg00qf 2324 12 that that WDT cord-022526-j9kg00qf 2324 13 may may MD cord-022526-j9kg00qf 2324 14 be be VB cord-022526-j9kg00qf 2324 15 likened liken VBN cord-022526-j9kg00qf 2324 16 to to IN cord-022526-j9kg00qf 2324 17 the the DT cord-022526-j9kg00qf 2324 18 outline outline NN cord-022526-j9kg00qf 2324 19 of of IN cord-022526-j9kg00qf 2324 20 an an DT cord-022526-j9kg00qf 2324 21 ornate ornate JJ cord-022526-j9kg00qf 2324 22 letter letter NN cord-022526-j9kg00qf 2324 23 B b NN cord-022526-j9kg00qf 2324 24 , , , cord-022526-j9kg00qf 2324 25 the the DT cord-022526-j9kg00qf 2324 26 upright upright JJ cord-022526-j9kg00qf 2324 27 stroke stroke NN cord-022526-j9kg00qf 2324 28 of of IN cord-022526-j9kg00qf 2324 29 the the DT cord-022526-j9kg00qf 2324 30 B b NN cord-022526-j9kg00qf 2324 31 being be VBG cord-022526-j9kg00qf 2324 32 on on IN cord-022526-j9kg00qf 2324 33 the the DT cord-022526-j9kg00qf 2324 34 lingual lingual JJ cord-022526-j9kg00qf 2324 35 aspect aspect NN cord-022526-j9kg00qf 2324 36 . . . cord-022526-j9kg00qf 2325 1 Dentin dentin NN cord-022526-j9kg00qf 2325 2 supports support VBZ cord-022526-j9kg00qf 2325 3 the the DT cord-022526-j9kg00qf 2325 4 enamel enamel NN cord-022526-j9kg00qf 2325 5 internally internally RB cord-022526-j9kg00qf 2325 6 , , , cord-022526-j9kg00qf 2325 7 cementum cementum NN cord-022526-j9kg00qf 2325 8 supports support VBZ cord-022526-j9kg00qf 2325 9 the the DT cord-022526-j9kg00qf 2325 10 enamel enamel JJ cord-022526-j9kg00qf 2325 11 lakes lake NNS cord-022526-j9kg00qf 2325 12 , , , cord-022526-j9kg00qf 2325 13 and and CC cord-022526-j9kg00qf 2325 14 the the DT cord-022526-j9kg00qf 2325 15 peripheral peripheral JJ cord-022526-j9kg00qf 2325 16 cementum cementum NN cord-022526-j9kg00qf 2325 17 fills fill VBZ cord-022526-j9kg00qf 2325 18 in in IN cord-022526-j9kg00qf 2325 19 the the DT cord-022526-j9kg00qf 2325 20 spaces space NNS cord-022526-j9kg00qf 2325 21 between between IN cord-022526-j9kg00qf 2325 22 the the DT cord-022526-j9kg00qf 2325 23 teeth tooth NNS cord-022526-j9kg00qf 2325 24 so so IN cord-022526-j9kg00qf 2325 25 that that IN cord-022526-j9kg00qf 2325 26 all all DT cord-022526-j9kg00qf 2325 27 six six CD cord-022526-j9kg00qf 2325 28 teeth tooth NNS cord-022526-j9kg00qf 2325 29 may may MD cord-022526-j9kg00qf 2325 30 function function VB cord-022526-j9kg00qf 2325 31 as as IN cord-022526-j9kg00qf 2325 32 a a DT cord-022526-j9kg00qf 2325 33 single single JJ cord-022526-j9kg00qf 2325 34 unit unit NN cord-022526-j9kg00qf 2325 35 , , , cord-022526-j9kg00qf 2325 36 that that RB cord-022526-j9kg00qf 2325 37 is is RB cord-022526-j9kg00qf 2325 38 , , , cord-022526-j9kg00qf 2325 39 the the DT cord-022526-j9kg00qf 2325 40 dental dental JJ cord-022526-j9kg00qf 2325 41 arcade arcade NN cord-022526-j9kg00qf 2325 42 . . . cord-022526-j9kg00qf 2326 1 Transverse transverse JJ cord-022526-j9kg00qf 2326 2 ridges ridge NNS cord-022526-j9kg00qf 2326 3 cross cross VBP cord-022526-j9kg00qf 2326 4 each each DT cord-022526-j9kg00qf 2326 5 tooth tooth NN cord-022526-j9kg00qf 2326 6 so so IN cord-022526-j9kg00qf 2326 7 that that IN cord-022526-j9kg00qf 2326 8 the the DT cord-022526-j9kg00qf 2326 9 whole whole JJ cord-022526-j9kg00qf 2326 10 maxillary maxillary JJ cord-022526-j9kg00qf 2326 11 arcade arcade NN cord-022526-j9kg00qf 2326 12 consists consist VBZ cord-022526-j9kg00qf 2326 13 of of IN cord-022526-j9kg00qf 2326 14 a a DT cord-022526-j9kg00qf 2326 15 serrated serrated JJ cord-022526-j9kg00qf 2326 16 edge edge NN cord-022526-j9kg00qf 2326 17 . . . cord-022526-j9kg00qf 2327 1 The the DT cord-022526-j9kg00qf 2327 2 serrations serration NNS cord-022526-j9kg00qf 2327 3 are be VBP cord-022526-j9kg00qf 2327 4 formed form VBN cord-022526-j9kg00qf 2327 5 so so IN cord-022526-j9kg00qf 2327 6 that that IN cord-022526-j9kg00qf 2327 7 a a DT cord-022526-j9kg00qf 2327 8 valley valley NN cord-022526-j9kg00qf 2327 9 is be VBZ cord-022526-j9kg00qf 2327 10 present present JJ cord-022526-j9kg00qf 2327 11 at at IN cord-022526-j9kg00qf 2327 12 the the DT cord-022526-j9kg00qf 2327 13 area area NN cord-022526-j9kg00qf 2327 14 of of IN cord-022526-j9kg00qf 2327 15 contact contact NN cord-022526-j9kg00qf 2327 16 with with IN cord-022526-j9kg00qf 2327 17 adjacent adjacent JJ cord-022526-j9kg00qf 2327 18 teeth tooth NNS cord-022526-j9kg00qf 2327 19 . . . cord-022526-j9kg00qf 2328 1 These these DT cord-022526-j9kg00qf 2328 2 serrations serration NNS cord-022526-j9kg00qf 2328 3 match match VBP cord-022526-j9kg00qf 2328 4 fitting fitting JJ cord-022526-j9kg00qf 2328 5 serrations serration NNS cord-022526-j9kg00qf 2328 6 on on IN cord-022526-j9kg00qf 2328 7 the the DT cord-022526-j9kg00qf 2328 8 mandibular mandibular JJ cord-022526-j9kg00qf 2328 9 arcade arcade NN cord-022526-j9kg00qf 2328 10 . . . cord-022526-j9kg00qf 2329 1 The the DT cord-022526-j9kg00qf 2329 2 true true JJ cord-022526-j9kg00qf 2329 3 roots root NNS cord-022526-j9kg00qf 2329 4 of of IN cord-022526-j9kg00qf 2329 5 the the DT cord-022526-j9kg00qf 2329 6 cheek cheek NN cord-022526-j9kg00qf 2329 7 teeth tooth NNS cord-022526-j9kg00qf 2329 8 are be VBP cord-022526-j9kg00qf 2329 9 short short JJ cord-022526-j9kg00qf 2329 10 compared compare VBN cord-022526-j9kg00qf 2329 11 with with IN cord-022526-j9kg00qf 2329 12 the the DT cord-022526-j9kg00qf 2329 13 total total JJ cord-022526-j9kg00qf 2329 14 length length NN cord-022526-j9kg00qf 2329 15 of of IN cord-022526-j9kg00qf 2329 16 the the DT cord-022526-j9kg00qf 2329 17 tooth tooth NN cord-022526-j9kg00qf 2329 18 . . . cord-022526-j9kg00qf 2330 1 Cheek cheek NN cord-022526-j9kg00qf 2330 2 teeth tooth NNS cord-022526-j9kg00qf 2330 3 have have VBP cord-022526-j9kg00qf 2330 4 three three CD cord-022526-j9kg00qf 2330 5 roots root NNS cord-022526-j9kg00qf 2330 6 : : : cord-022526-j9kg00qf 2330 7 two two CD cord-022526-j9kg00qf 2330 8 small small JJ cord-022526-j9kg00qf 2330 9 lateral lateral JJ cord-022526-j9kg00qf 2330 10 roots root NNS cord-022526-j9kg00qf 2330 11 and and CC cord-022526-j9kg00qf 2330 12 one one CD cord-022526-j9kg00qf 2330 13 large large JJ cord-022526-j9kg00qf 2330 14 medial medial JJ cord-022526-j9kg00qf 2330 15 root root NN cord-022526-j9kg00qf 2330 16 . . . cord-022526-j9kg00qf 2331 1 By by IN cord-022526-j9kg00qf 2331 2 custom custom NN cord-022526-j9kg00qf 2331 3 , , , cord-022526-j9kg00qf 2331 4 that that DT cord-022526-j9kg00qf 2331 5 portion portion NN cord-022526-j9kg00qf 2331 6 of of IN cord-022526-j9kg00qf 2331 7 the the DT cord-022526-j9kg00qf 2331 8 crown crown NN cord-022526-j9kg00qf 2331 9 embedded embed VBN cord-022526-j9kg00qf 2331 10 within within IN cord-022526-j9kg00qf 2331 11 the the DT cord-022526-j9kg00qf 2331 12 dental dental JJ cord-022526-j9kg00qf 2331 13 alveolus alveolus NNP cord-022526-j9kg00qf 2331 14 is be VBZ cord-022526-j9kg00qf 2331 15 referred refer VBN cord-022526-j9kg00qf 2331 16 to to IN cord-022526-j9kg00qf 2331 17 as as IN cord-022526-j9kg00qf 2331 18 the the DT cord-022526-j9kg00qf 2331 19 reserve reserve NN cord-022526-j9kg00qf 2331 20 crown crown NN cord-022526-j9kg00qf 2331 21 , , , cord-022526-j9kg00qf 2331 22 and and CC cord-022526-j9kg00qf 2331 23 the the DT cord-022526-j9kg00qf 2331 24 term term NN cord-022526-j9kg00qf 2331 25 root root NN cord-022526-j9kg00qf 2331 26 is be VBZ cord-022526-j9kg00qf 2331 27 confined confine VBN cord-022526-j9kg00qf 2331 28 to to IN cord-022526-j9kg00qf 2331 29 that that DT cord-022526-j9kg00qf 2331 30 area area NN cord-022526-j9kg00qf 2331 31 of of IN cord-022526-j9kg00qf 2331 32 the the DT cord-022526-j9kg00qf 2331 33 tooth tooth NN cord-022526-j9kg00qf 2331 34 that that WDT cord-022526-j9kg00qf 2331 35 is be VBZ cord-022526-j9kg00qf 2331 36 comparatively comparatively RB cord-022526-j9kg00qf 2331 37 short short JJ cord-022526-j9kg00qf 2331 38 and and CC cord-022526-j9kg00qf 2331 39 enamel enamel JJ cord-022526-j9kg00qf 2331 40 free free JJ cord-022526-j9kg00qf 2331 41 . . . cord-022526-j9kg00qf 2332 1 Wear wear VB cord-022526-j9kg00qf 2332 2 on on IN cord-022526-j9kg00qf 2332 3 the the DT cord-022526-j9kg00qf 2332 4 tooth tooth NN cord-022526-j9kg00qf 2332 5 gradually gradually RB cord-022526-j9kg00qf 2332 6 exposes expose VBZ cord-022526-j9kg00qf 2332 7 the the DT cord-022526-j9kg00qf 2332 8 reserve reserve NN cord-022526-j9kg00qf 2332 9 crown crown NN cord-022526-j9kg00qf 2332 10 , , , cord-022526-j9kg00qf 2332 11 and and CC cord-022526-j9kg00qf 2332 12 the the DT cord-022526-j9kg00qf 2332 13 roots root NNS cord-022526-j9kg00qf 2332 14 lengthen lengthen VBP cord-022526-j9kg00qf 2332 15 . . . cord-022526-j9kg00qf 2333 1 In in IN cord-022526-j9kg00qf 2333 2 an an DT cord-022526-j9kg00qf 2333 3 adult adult NN cord-022526-j9kg00qf 2333 4 1000-lb 1000-lb CD cord-022526-j9kg00qf 2333 5 horse horse NN cord-022526-j9kg00qf 2333 6 the the DT cord-022526-j9kg00qf 2333 7 maxillary maxillary JJ cord-022526-j9kg00qf 2333 8 cheek cheek NN cord-022526-j9kg00qf 2333 9 teeth tooth NNS cord-022526-j9kg00qf 2333 10 are be VBP cord-022526-j9kg00qf 2333 11 between between IN cord-022526-j9kg00qf 2333 12 8.0 8.0 CD cord-022526-j9kg00qf 2333 13 and and CC cord-022526-j9kg00qf 2333 14 8.5 8.5 CD cord-022526-j9kg00qf 2333 15 cm cm NNS cord-022526-j9kg00qf 2333 16 in in IN cord-022526-j9kg00qf 2333 17 length length NN cord-022526-j9kg00qf 2333 18 . . . cord-022526-j9kg00qf 2334 1 Dental dental JJ cord-022526-j9kg00qf 2334 2 wear wear NN cord-022526-j9kg00qf 2334 3 accounts account NNS cord-022526-j9kg00qf 2334 4 for for IN cord-022526-j9kg00qf 2334 5 erosion erosion NN cord-022526-j9kg00qf 2334 6 and and CC cord-022526-j9kg00qf 2334 7 loss loss NN cord-022526-j9kg00qf 2334 8 of of IN cord-022526-j9kg00qf 2334 9 tooth tooth NN cord-022526-j9kg00qf 2334 10 substance substance NN cord-022526-j9kg00qf 2334 11 at at IN cord-022526-j9kg00qf 2334 12 a a DT cord-022526-j9kg00qf 2334 13 rate rate NN cord-022526-j9kg00qf 2334 14 of of IN cord-022526-j9kg00qf 2334 15 2 2 CD cord-022526-j9kg00qf 2334 16 mm mm NN cord-022526-j9kg00qf 2334 17 / / SYM cord-022526-j9kg00qf 2334 18 yr yr NN cord-022526-j9kg00qf 2334 19 . . . cord-022526-j9kg00qf 2335 1 The the DT cord-022526-j9kg00qf 2335 2 pulp pulp NN cord-022526-j9kg00qf 2335 3 chambers chamber NNS cord-022526-j9kg00qf 2335 4 of of IN cord-022526-j9kg00qf 2335 5 the the DT cord-022526-j9kg00qf 2335 6 teeth tooth NNS cord-022526-j9kg00qf 2335 7 are be VBP cord-022526-j9kg00qf 2335 8 also also RB cord-022526-j9kg00qf 2335 9 complex complex JJ cord-022526-j9kg00qf 2335 10 . . . cord-022526-j9kg00qf 2336 1 The the DT cord-022526-j9kg00qf 2336 2 incisors incisor NNS cord-022526-j9kg00qf 2336 3 and and CC cord-022526-j9kg00qf 2336 4 canines canine NNS cord-022526-j9kg00qf 2336 5 have have VBP cord-022526-j9kg00qf 2336 6 a a DT cord-022526-j9kg00qf 2336 7 single single JJ cord-022526-j9kg00qf 2336 8 pulp pulp NN cord-022526-j9kg00qf 2336 9 chamber chamber NN cord-022526-j9kg00qf 2336 10 . . . cord-022526-j9kg00qf 2337 1 The the DT cord-022526-j9kg00qf 2337 2 mandibular mandibular JJ cord-022526-j9kg00qf 2337 3 cheek cheek NN cord-022526-j9kg00qf 2337 4 teeth tooth NNS cord-022526-j9kg00qf 2337 5 have have VBP cord-022526-j9kg00qf 2337 6 two two CD cord-022526-j9kg00qf 2337 7 roots root NNS cord-022526-j9kg00qf 2337 8 and and CC cord-022526-j9kg00qf 2337 9 two two CD cord-022526-j9kg00qf 2337 10 separate separate JJ cord-022526-j9kg00qf 2337 11 pulp pulp NN cord-022526-j9kg00qf 2337 12 chambers chamber NNS cord-022526-j9kg00qf 2337 13 . . . cord-022526-j9kg00qf 2338 1 The the DT cord-022526-j9kg00qf 2338 2 maxillary maxillary JJ cord-022526-j9kg00qf 2338 3 cheek cheek NN cord-022526-j9kg00qf 2338 4 teeth tooth NNS cord-022526-j9kg00qf 2338 5 , , , cord-022526-j9kg00qf 2338 6 although although IN cord-022526-j9kg00qf 2338 7 they -PRON- PRP cord-022526-j9kg00qf 2338 8 have have VBP cord-022526-j9kg00qf 2338 9 three three CD cord-022526-j9kg00qf 2338 10 roots root NNS cord-022526-j9kg00qf 2338 11 , , , cord-022526-j9kg00qf 2338 12 have have VBP cord-022526-j9kg00qf 2338 13 in in IN cord-022526-j9kg00qf 2338 14 fact fact NN cord-022526-j9kg00qf 2338 15 five five CD cord-022526-j9kg00qf 2338 16 pulp pulp NN cord-022526-j9kg00qf 2338 17 chambers chamber NNS cord-022526-j9kg00qf 2338 18 . . . cord-022526-j9kg00qf 2339 1 As as IN cord-022526-j9kg00qf 2339 2 occlusal occlusal JJ cord-022526-j9kg00qf 2339 3 wear wear NN cord-022526-j9kg00qf 2339 4 proceeds proceed NNS cord-022526-j9kg00qf 2339 5 , , , cord-022526-j9kg00qf 2339 6 deposition deposition NN cord-022526-j9kg00qf 2339 7 of of IN cord-022526-j9kg00qf 2339 8 secondary secondary JJ cord-022526-j9kg00qf 2339 9 dentin dentin NN cord-022526-j9kg00qf 2339 10 within within IN cord-022526-j9kg00qf 2339 11 the the DT cord-022526-j9kg00qf 2339 12 pulp pulp NN cord-022526-j9kg00qf 2339 13 chambers chamber NNS cord-022526-j9kg00qf 2339 14 protects protect VBZ cord-022526-j9kg00qf 2339 15 the the DT cord-022526-j9kg00qf 2339 16 chambers chamber NNS cord-022526-j9kg00qf 2339 17 ( ( -LRB- cord-022526-j9kg00qf 2339 18 e.g. e.g. RB cord-022526-j9kg00qf 2339 19 , , , cord-022526-j9kg00qf 2339 20 the the DT cord-022526-j9kg00qf 2339 21 dental dental JJ cord-022526-j9kg00qf 2339 22 star star NNP cord-022526-j9kg00qf 2339 23 , , , cord-022526-j9kg00qf 2339 24 medial medial JJ cord-022526-j9kg00qf 2339 25 to to IN cord-022526-j9kg00qf 2339 26 the the DT cord-022526-j9kg00qf 2339 27 infundibulum infundibulum NN cord-022526-j9kg00qf 2339 28 on on IN cord-022526-j9kg00qf 2339 29 the the DT cord-022526-j9kg00qf 2339 30 incisor incisor NN cord-022526-j9kg00qf 2339 31 teeth tooth NNS cord-022526-j9kg00qf 2339 32 ) ) -RRB- cord-022526-j9kg00qf 2339 33 . . . cord-022526-j9kg00qf 2340 1 In in IN cord-022526-j9kg00qf 2340 2 the the DT cord-022526-j9kg00qf 2340 3 mandibular mandibular JJ cord-022526-j9kg00qf 2340 4 cheek cheek NN cord-022526-j9kg00qf 2340 5 teeth tooth NNS cord-022526-j9kg00qf 2340 6 the the DT cord-022526-j9kg00qf 2340 7 transverse transverse JJ cord-022526-j9kg00qf 2340 8 folding folding NN cord-022526-j9kg00qf 2340 9 of of IN cord-022526-j9kg00qf 2340 10 the the DT cord-022526-j9kg00qf 2340 11 enamel enamel JJ cord-022526-j9kg00qf 2340 12 anlage anlage NN cord-022526-j9kg00qf 2340 13 ( ( -LRB- cord-022526-j9kg00qf 2340 14 during during IN cord-022526-j9kg00qf 2340 15 morphogenesis morphogenesis NN cord-022526-j9kg00qf 2340 16 of of IN cord-022526-j9kg00qf 2340 17 the the DT cord-022526-j9kg00qf 2340 18 tooth tooth NN cord-022526-j9kg00qf 2340 19 ) ) -RRB- cord-022526-j9kg00qf 2340 20 does do VBZ cord-022526-j9kg00qf 2340 21 not not RB cord-022526-j9kg00qf 2340 22 take take VB cord-022526-j9kg00qf 2340 23 place place NN cord-022526-j9kg00qf 2340 24 , , , cord-022526-j9kg00qf 2340 25 and and CC cord-022526-j9kg00qf 2340 26 the the DT cord-022526-j9kg00qf 2340 27 occlusal occlusal NN cord-022526-j9kg00qf 2340 28 surface surface NN cord-022526-j9kg00qf 2340 29 is be VBZ cord-022526-j9kg00qf 2340 30 a a DT cord-022526-j9kg00qf 2340 31 simple simple JJ cord-022526-j9kg00qf 2340 32 surface surface NN cord-022526-j9kg00qf 2340 33 of of IN cord-022526-j9kg00qf 2340 34 central central JJ cord-022526-j9kg00qf 2340 35 dentin dentin NN cord-022526-j9kg00qf 2340 36 surrounded surround VBN cord-022526-j9kg00qf 2340 37 by by IN cord-022526-j9kg00qf 2340 38 enamel enamel NN cord-022526-j9kg00qf 2340 39 . . . cord-022526-j9kg00qf 2341 1 Each each DT cord-022526-j9kg00qf 2341 2 tooth tooth NN cord-022526-j9kg00qf 2341 3 then then RB cord-022526-j9kg00qf 2341 4 is be VBZ cord-022526-j9kg00qf 2341 5 conformed conform VBN cord-022526-j9kg00qf 2341 6 to to IN cord-022526-j9kg00qf 2341 7 a a DT cord-022526-j9kg00qf 2341 8 single single JJ cord-022526-j9kg00qf 2341 9 arcade arcade NN cord-022526-j9kg00qf 2341 10 by by IN cord-022526-j9kg00qf 2341 11 the the DT cord-022526-j9kg00qf 2341 12 presence presence NN cord-022526-j9kg00qf 2341 13 of of IN cord-022526-j9kg00qf 2341 14 peripheral peripheral JJ cord-022526-j9kg00qf 2341 15 crown crown NN cord-022526-j9kg00qf 2341 16 cementum cementum NN cord-022526-j9kg00qf 2341 17 . . . cord-022526-j9kg00qf 2342 1 The the DT cord-022526-j9kg00qf 2342 2 oral oral JJ cord-022526-j9kg00qf 2342 3 cavity cavity NN cord-022526-j9kg00qf 2342 4 and and CC cord-022526-j9kg00qf 2342 5 oropharynx oropharynx NN cord-022526-j9kg00qf 2342 6 are be VBP cord-022526-j9kg00qf 2342 7 subject subject JJ cord-022526-j9kg00qf 2342 8 to to IN cord-022526-j9kg00qf 2342 9 a a DT cord-022526-j9kg00qf 2342 10 variety variety NN cord-022526-j9kg00qf 2342 11 of of IN cord-022526-j9kg00qf 2342 12 diseases disease NNS cord-022526-j9kg00qf 2342 13 . . . cord-022526-j9kg00qf 2343 1 However however RB cord-022526-j9kg00qf 2343 2 , , , cord-022526-j9kg00qf 2343 3 many many JJ cord-022526-j9kg00qf 2343 4 conditions condition NNS cord-022526-j9kg00qf 2343 5 affecting affect VBG cord-022526-j9kg00qf 2343 6 the the DT cord-022526-j9kg00qf 2343 7 first first JJ cord-022526-j9kg00qf 2343 8 portion portion NN cord-022526-j9kg00qf 2343 9 of of IN cord-022526-j9kg00qf 2343 10 the the DT cord-022526-j9kg00qf 2343 11 alimentary alimentary JJ cord-022526-j9kg00qf 2343 12 system system NN cord-022526-j9kg00qf 2343 13 produce produce VBP cord-022526-j9kg00qf 2343 14 the the DT cord-022526-j9kg00qf 2343 15 same same JJ cord-022526-j9kg00qf 2343 16 clinical clinical JJ cord-022526-j9kg00qf 2343 17 signs sign NNS cord-022526-j9kg00qf 2343 18 , , , cord-022526-j9kg00qf 2343 19 regardless regardless RB cord-022526-j9kg00qf 2343 20 of of IN cord-022526-j9kg00qf 2343 21 their -PRON- PRP$ cord-022526-j9kg00qf 2343 22 cause cause NN cord-022526-j9kg00qf 2343 23 . . . cord-022526-j9kg00qf 2344 1 The the DT cord-022526-j9kg00qf 2344 2 clinical clinical JJ cord-022526-j9kg00qf 2344 3 signs sign NNS cord-022526-j9kg00qf 2344 4 may may MD cord-022526-j9kg00qf 2344 5 include include VB cord-022526-j9kg00qf 2344 6 inappetance inappetance NN cord-022526-j9kg00qf 2344 7 or or CC cord-022526-j9kg00qf 2344 8 reluctance reluctance NN cord-022526-j9kg00qf 2344 9 to to TO cord-022526-j9kg00qf 2344 10 eat eat VB cord-022526-j9kg00qf 2344 11 , , , cord-022526-j9kg00qf 2344 12 pain pain VB cord-022526-j9kg00qf 2344 13 on on IN cord-022526-j9kg00qf 2344 14 eating eat VBG cord-022526-j9kg00qf 2344 15 or or CC cord-022526-j9kg00qf 2344 16 swallowing swallow VBG cord-022526-j9kg00qf 2344 17 , , , cord-022526-j9kg00qf 2344 18 oral oral JJ cord-022526-j9kg00qf 2344 19 swelling swelling NN cord-022526-j9kg00qf 2344 20 , , , cord-022526-j9kg00qf 2344 21 oral oral JJ cord-022526-j9kg00qf 2344 22 discharge discharge NN cord-022526-j9kg00qf 2344 23 , , , cord-022526-j9kg00qf 2344 24 and and CC cord-022526-j9kg00qf 2344 25 fetid fetid JJ cord-022526-j9kg00qf 2344 26 breath breath NN cord-022526-j9kg00qf 2344 27 . . . cord-022526-j9kg00qf 2345 1 Affected affected JJ cord-022526-j9kg00qf 2345 2 animals animal NNS cord-022526-j9kg00qf 2345 3 may may MD cord-022526-j9kg00qf 2345 4 show show VB cord-022526-j9kg00qf 2345 5 some some DT cord-022526-j9kg00qf 2345 6 interest interest NN cord-022526-j9kg00qf 2345 7 in in IN cord-022526-j9kg00qf 2345 8 food food NN cord-022526-j9kg00qf 2345 9 but but CC cord-022526-j9kg00qf 2345 10 hesitate hesitate VBP cord-022526-j9kg00qf 2345 11 to to TO cord-022526-j9kg00qf 2345 12 eat eat VB cord-022526-j9kg00qf 2345 13 it -PRON- PRP cord-022526-j9kg00qf 2345 14 . . . cord-022526-j9kg00qf 2346 1 Salivation salivation NN cord-022526-j9kg00qf 2346 2 may may MD cord-022526-j9kg00qf 2346 3 be be VB cord-022526-j9kg00qf 2346 4 excessive excessive JJ cord-022526-j9kg00qf 2346 5 and and CC cord-022526-j9kg00qf 2346 6 may may MD cord-022526-j9kg00qf 2346 7 be be VB cord-022526-j9kg00qf 2346 8 contaminated contaminate VBN cord-022526-j9kg00qf 2346 9 with with IN cord-022526-j9kg00qf 2346 10 purulent purulent JJ cord-022526-j9kg00qf 2346 11 exudate exudate NN cord-022526-j9kg00qf 2346 12 or or CC cord-022526-j9kg00qf 2346 13 blood blood NN cord-022526-j9kg00qf 2346 14 . . . cord-022526-j9kg00qf 2347 1 The the DT cord-022526-j9kg00qf 2347 2 occurrence occurrence NN cord-022526-j9kg00qf 2347 3 of of IN cord-022526-j9kg00qf 2347 4 bruxism bruxism NN cord-022526-j9kg00qf 2347 5 ( ( -LRB- cord-022526-j9kg00qf 2347 6 i.e. i.e. FW cord-022526-j9kg00qf 2347 7 , , , cord-022526-j9kg00qf 2347 8 grinding grind VBG cord-022526-j9kg00qf 2347 9 of of IN cord-022526-j9kg00qf 2347 10 teeth tooth NNS cord-022526-j9kg00qf 2347 11 ) ) -RRB- cord-022526-j9kg00qf 2347 12 can can MD cord-022526-j9kg00qf 2347 13 indicate indicate VB cord-022526-j9kg00qf 2347 14 discomfort discomfort NN cord-022526-j9kg00qf 2347 15 in in IN cord-022526-j9kg00qf 2347 16 other other JJ cord-022526-j9kg00qf 2347 17 areas area NNS cord-022526-j9kg00qf 2347 18 of of IN cord-022526-j9kg00qf 2347 19 the the DT cord-022526-j9kg00qf 2347 20 alimentary alimentary JJ cord-022526-j9kg00qf 2347 21 tract tract NN cord-022526-j9kg00qf 2347 22 ; ; : cord-022526-j9kg00qf 2347 23 for for IN cord-022526-j9kg00qf 2347 24 example example NN cord-022526-j9kg00qf 2347 25 , , , cord-022526-j9kg00qf 2347 26 bruxism bruxism NN cord-022526-j9kg00qf 2347 27 and and CC cord-022526-j9kg00qf 2347 28 frothing froth VBG cord-022526-j9kg00qf 2347 29 oral oral JJ cord-022526-j9kg00qf 2347 30 saliva saliva NN cord-022526-j9kg00qf 2347 31 are be VBP cord-022526-j9kg00qf 2347 32 characteristic characteristic JJ cord-022526-j9kg00qf 2347 33 features feature NNS cord-022526-j9kg00qf 2347 34 of of IN cord-022526-j9kg00qf 2347 35 gastric gastric JJ cord-022526-j9kg00qf 2347 36 ulceration ulceration NN cord-022526-j9kg00qf 2347 37 in in IN cord-022526-j9kg00qf 2347 38 the the DT cord-022526-j9kg00qf 2347 39 horse horse NN cord-022526-j9kg00qf 2347 40 . . . cord-022526-j9kg00qf 2348 1 The the DT cord-022526-j9kg00qf 2348 2 clinician clinician NN cord-022526-j9kg00qf 2348 3 needs need VBZ cord-022526-j9kg00qf 2348 4 to to TO cord-022526-j9kg00qf 2348 5 be be VB cord-022526-j9kg00qf 2348 6 aware aware JJ cord-022526-j9kg00qf 2348 7 that that IN cord-022526-j9kg00qf 2348 8 considerable considerable JJ cord-022526-j9kg00qf 2348 9 weight weight NN cord-022526-j9kg00qf 2348 10 loss loss NN cord-022526-j9kg00qf 2348 11 can can MD cord-022526-j9kg00qf 2348 12 occur occur VB cord-022526-j9kg00qf 2348 13 rapidly rapidly RB cord-022526-j9kg00qf 2348 14 with with IN cord-022526-j9kg00qf 2348 15 inability inability NN cord-022526-j9kg00qf 2348 16 to to TO cord-022526-j9kg00qf 2348 17 feed feed VB cord-022526-j9kg00qf 2348 18 and and CC cord-022526-j9kg00qf 2348 19 swallow swallow VB cord-022526-j9kg00qf 2348 20 . . . cord-022526-j9kg00qf 2349 1 Diseases disease NNS cord-022526-j9kg00qf 2349 2 that that WDT cord-022526-j9kg00qf 2349 3 result result VBP cord-022526-j9kg00qf 2349 4 in in IN cord-022526-j9kg00qf 2349 5 denervation denervation NN cord-022526-j9kg00qf 2349 6 of of IN cord-022526-j9kg00qf 2349 7 the the DT cord-022526-j9kg00qf 2349 8 pharynx pharynx NN cord-022526-j9kg00qf 2349 9 and and CC cord-022526-j9kg00qf 2349 10 inappropriate inappropriate JJ cord-022526-j9kg00qf 2349 11 swallowing swallowing NN cord-022526-j9kg00qf 2349 12 can can MD cord-022526-j9kg00qf 2349 13 have have VB cord-022526-j9kg00qf 2349 14 the the DT cord-022526-j9kg00qf 2349 15 complication complication NN cord-022526-j9kg00qf 2349 16 of of IN cord-022526-j9kg00qf 2349 17 inhalation inhalation NN cord-022526-j9kg00qf 2349 18 pneumonia pneumonia NN cord-022526-j9kg00qf 2349 19 . . . cord-022526-j9kg00qf 2350 1 After after IN cord-022526-j9kg00qf 2350 2 a a DT cord-022526-j9kg00qf 2350 3 complete complete JJ cord-022526-j9kg00qf 2350 4 physical physical JJ cord-022526-j9kg00qf 2350 5 examination examination NN cord-022526-j9kg00qf 2350 6 and and CC cord-022526-j9kg00qf 2350 7 ascertaining ascertain VBG cord-022526-j9kg00qf 2350 8 the the DT cord-022526-j9kg00qf 2350 9 history history NN cord-022526-j9kg00qf 2350 10 , , , cord-022526-j9kg00qf 2350 11 the the DT cord-022526-j9kg00qf 2350 12 clinician clinician NN cord-022526-j9kg00qf 2350 13 should should MD cord-022526-j9kg00qf 2350 14 approach approach VB cord-022526-j9kg00qf 2350 15 examination examination NN cord-022526-j9kg00qf 2350 16 of of IN cord-022526-j9kg00qf 2350 17 the the DT cord-022526-j9kg00qf 2350 18 mouth mouth NN cord-022526-j9kg00qf 2350 19 systematically systematically RB cord-022526-j9kg00qf 2350 20 in in IN cord-022526-j9kg00qf 2350 21 all all DT cord-022526-j9kg00qf 2350 22 cases case NNS cord-022526-j9kg00qf 2350 23 . . . cord-022526-j9kg00qf 2351 1 One one PRP cord-022526-j9kg00qf 2351 2 can can MD cord-022526-j9kg00qf 2351 3 examine examine VB cord-022526-j9kg00qf 2351 4 a a DT cord-022526-j9kg00qf 2351 5 considerable considerable JJ cord-022526-j9kg00qf 2351 6 portion portion NN cord-022526-j9kg00qf 2351 7 of of IN cord-022526-j9kg00qf 2351 8 the the DT cord-022526-j9kg00qf 2351 9 mouth mouth NN cord-022526-j9kg00qf 2351 10 and and CC cord-022526-j9kg00qf 2351 11 teeth tooth NNS cord-022526-j9kg00qf 2351 12 from from IN cord-022526-j9kg00qf 2351 13 the the DT cord-022526-j9kg00qf 2351 14 outside outside NN cord-022526-j9kg00qf 2351 15 by by IN cord-022526-j9kg00qf 2351 16 palpation palpation NN cord-022526-j9kg00qf 2351 17 of of IN cord-022526-j9kg00qf 2351 18 the the DT cord-022526-j9kg00qf 2351 19 structures structure NNS cord-022526-j9kg00qf 2351 20 through through IN cord-022526-j9kg00qf 2351 21 the the DT cord-022526-j9kg00qf 2351 22 folds fold NNS cord-022526-j9kg00qf 2351 23 of of IN cord-022526-j9kg00qf 2351 24 the the DT cord-022526-j9kg00qf 2351 25 cheek cheek NN cord-022526-j9kg00qf 2351 26 . . . cord-022526-j9kg00qf 2352 1 Most Most JJS cord-022526-j9kg00qf 2352 2 horses horse NNS cord-022526-j9kg00qf 2352 3 allow allow VBP cord-022526-j9kg00qf 2352 4 an an DT cord-022526-j9kg00qf 2352 5 oral oral JJ cord-022526-j9kg00qf 2352 6 examination examination NN cord-022526-j9kg00qf 2352 7 without without IN cord-022526-j9kg00qf 2352 8 sedation sedation NN cord-022526-j9kg00qf 2352 9 or or CC cord-022526-j9kg00qf 2352 10 the the DT cord-022526-j9kg00qf 2352 11 use use NN cord-022526-j9kg00qf 2352 12 of of IN cord-022526-j9kg00qf 2352 13 an an DT cord-022526-j9kg00qf 2352 14 oral oral JJ cord-022526-j9kg00qf 2352 15 speculum speculum NN cord-022526-j9kg00qf 2352 16 . . . cord-022526-j9kg00qf 2353 1 In in IN cord-022526-j9kg00qf 2353 2 many many JJ cord-022526-j9kg00qf 2353 3 cases case NNS cord-022526-j9kg00qf 2353 4 , , , cord-022526-j9kg00qf 2353 5 however however RB cord-022526-j9kg00qf 2353 6 , , , cord-022526-j9kg00qf 2353 7 one one CD cord-022526-j9kg00qf 2353 8 best good JJS cord-022526-j9kg00qf 2353 9 achieves achieve VBZ cord-022526-j9kg00qf 2353 10 the the DT cord-022526-j9kg00qf 2353 11 detailed detailed JJ cord-022526-j9kg00qf 2353 12 oral oral JJ cord-022526-j9kg00qf 2353 13 examination examination NN cord-022526-j9kg00qf 2353 14 by by IN cord-022526-j9kg00qf 2353 15 sedation sedation NN cord-022526-j9kg00qf 2353 16 and and CC cord-022526-j9kg00qf 2353 17 the the DT cord-022526-j9kg00qf 2353 18 use use NN cord-022526-j9kg00qf 2353 19 of of IN cord-022526-j9kg00qf 2353 20 an an DT cord-022526-j9kg00qf 2353 21 oral oral JJ cord-022526-j9kg00qf 2353 22 speculum speculum NN cord-022526-j9kg00qf 2353 23 and and CC cord-022526-j9kg00qf 2353 24 a a DT cord-022526-j9kg00qf 2353 25 light light JJ cord-022526-j9kg00qf 2353 26 source source NN cord-022526-j9kg00qf 2353 27 . . . cord-022526-j9kg00qf 2354 1 One one PRP cord-022526-j9kg00qf 2354 2 should should MD cord-022526-j9kg00qf 2354 3 irrigate irrigate VB cord-022526-j9kg00qf 2354 4 the the DT cord-022526-j9kg00qf 2354 5 mouth mouth NN cord-022526-j9kg00qf 2354 6 to to TO cord-022526-j9kg00qf 2354 7 wash wash VB cord-022526-j9kg00qf 2354 8 out out RP cord-022526-j9kg00qf 2354 9 retained retain VBN cord-022526-j9kg00qf 2354 10 food food NN cord-022526-j9kg00qf 2354 11 material material NN cord-022526-j9kg00qf 2354 12 so so IN cord-022526-j9kg00qf 2354 13 as as IN cord-022526-j9kg00qf 2354 14 to to TO cord-022526-j9kg00qf 2354 15 be be VB cord-022526-j9kg00qf 2354 16 able able JJ cord-022526-j9kg00qf 2354 17 to to TO cord-022526-j9kg00qf 2354 18 inspect inspect VB cord-022526-j9kg00qf 2354 19 and and CC cord-022526-j9kg00qf 2354 20 palpate palpate VB cord-022526-j9kg00qf 2354 21 the the DT cord-022526-j9kg00qf 2354 22 lips lip NNS cord-022526-j9kg00qf 2354 23 , , , cord-022526-j9kg00qf 2354 24 cheeks cheek NNS cord-022526-j9kg00qf 2354 25 , , , cord-022526-j9kg00qf 2354 26 teeth tooth NNS cord-022526-j9kg00qf 2354 27 , , , cord-022526-j9kg00qf 2354 28 and and CC cord-022526-j9kg00qf 2354 29 gums gum NNS cord-022526-j9kg00qf 2354 30 . . . cord-022526-j9kg00qf 2355 1 The the DT cord-022526-j9kg00qf 2355 2 classic classic JJ cord-022526-j9kg00qf 2355 3 signs sign NNS cord-022526-j9kg00qf 2355 4 of of IN cord-022526-j9kg00qf 2355 5 dental dental JJ cord-022526-j9kg00qf 2355 6 disease disease NN cord-022526-j9kg00qf 2355 7 in in IN cord-022526-j9kg00qf 2355 8 the the DT cord-022526-j9kg00qf 2355 9 horse horse NN cord-022526-j9kg00qf 2355 10 include include VBP cord-022526-j9kg00qf 2355 11 difficulty difficulty NN cord-022526-j9kg00qf 2355 12 and and CC cord-022526-j9kg00qf 2355 13 slowness slowness NN cord-022526-j9kg00qf 2355 14 in in IN cord-022526-j9kg00qf 2355 15 feeding feeding NN cord-022526-j9kg00qf 2355 16 , , , cord-022526-j9kg00qf 2355 17 together together RB cord-022526-j9kg00qf 2355 18 with with IN cord-022526-j9kg00qf 2355 19 a a DT cord-022526-j9kg00qf 2355 20 progressive progressive JJ cord-022526-j9kg00qf 2355 21 unthriftiness unthriftiness NN cord-022526-j9kg00qf 2355 22 and and CC cord-022526-j9kg00qf 2355 23 loss loss NN cord-022526-j9kg00qf 2355 24 of of IN cord-022526-j9kg00qf 2355 25 body body NN cord-022526-j9kg00qf 2355 26 condition condition NN cord-022526-j9kg00qf 2355 27 . . . cord-022526-j9kg00qf 2356 1 In in IN cord-022526-j9kg00qf 2356 2 some some DT cord-022526-j9kg00qf 2356 3 instances instance NNS cord-022526-j9kg00qf 2356 4 , , , cord-022526-j9kg00qf 2356 5 the the DT cord-022526-j9kg00qf 2356 6 horse horse NN cord-022526-j9kg00qf 2356 7 may may MD cord-022526-j9kg00qf 2356 8 quid quid VB cord-022526-j9kg00qf 2356 9 , , , cord-022526-j9kg00qf 2356 10 that that RB cord-022526-j9kg00qf 2356 11 is is RB cord-022526-j9kg00qf 2356 12 , , , cord-022526-j9kg00qf 2356 13 it -PRON- PRP cord-022526-j9kg00qf 2356 14 may may MD cord-022526-j9kg00qf 2356 15 drop drop VB cord-022526-j9kg00qf 2356 16 poorly poorly RB cord-022526-j9kg00qf 2356 17 masticated masticate VBN cord-022526-j9kg00qf 2356 18 food food NN cord-022526-j9kg00qf 2356 19 boluses bolus NNS cord-022526-j9kg00qf 2356 20 from from IN cord-022526-j9kg00qf 2356 21 the the DT cord-022526-j9kg00qf 2356 22 mouth mouth NN cord-022526-j9kg00qf 2356 23 , , , cord-022526-j9kg00qf 2356 24 and and CC cord-022526-j9kg00qf 2356 25 halitosis halitosis NN cord-022526-j9kg00qf 2356 26 may may MD cord-022526-j9kg00qf 2356 27 be be VB cord-022526-j9kg00qf 2356 28 obvious obvious JJ cord-022526-j9kg00qf 2356 29 . . . cord-022526-j9kg00qf 2357 1 Additional additional JJ cord-022526-j9kg00qf 2357 2 problems problem NNS cord-022526-j9kg00qf 2357 3 reported report VBN cord-022526-j9kg00qf 2357 4 by by IN cord-022526-j9kg00qf 2357 5 owners owner NNS cord-022526-j9kg00qf 2357 6 include include VBP cord-022526-j9kg00qf 2357 7 bitting bit VBG cord-022526-j9kg00qf 2357 8 and and CC cord-022526-j9kg00qf 2357 9 riding ride VBG cord-022526-j9kg00qf 2357 10 problems problem NNS cord-022526-j9kg00qf 2357 11 and and CC cord-022526-j9kg00qf 2357 12 headshaking headshaking NN cord-022526-j9kg00qf 2357 13 or or CC cord-022526-j9kg00qf 2357 14 head head NN cord-022526-j9kg00qf 2357 15 shyness shyness NN cord-022526-j9kg00qf 2357 16 . . . cord-022526-j9kg00qf 2358 1 Facial facial JJ cord-022526-j9kg00qf 2358 2 or or CC cord-022526-j9kg00qf 2358 3 mandibular mandibular JJ cord-022526-j9kg00qf 2358 4 swelling swelling NN cord-022526-j9kg00qf 2358 5 may may MD cord-022526-j9kg00qf 2358 6 occur occur VB cord-022526-j9kg00qf 2358 7 . . . cord-022526-j9kg00qf 2359 1 Nasal nasal NN cord-022526-j9kg00qf 2359 2 discharge discharge NN cord-022526-j9kg00qf 2359 3 can can MD cord-022526-j9kg00qf 2359 4 result result VB cord-022526-j9kg00qf 2359 5 from from IN cord-022526-j9kg00qf 2359 6 dental dental JJ cord-022526-j9kg00qf 2359 7 disease disease NN cord-022526-j9kg00qf 2359 8 associated associate VBN cord-022526-j9kg00qf 2359 9 with with IN cord-022526-j9kg00qf 2359 10 maxillary maxillary JJ cord-022526-j9kg00qf 2359 11 sinus sinus NN cord-022526-j9kg00qf 2359 12 empyema empyema NN cord-022526-j9kg00qf 2359 13 . . . cord-022526-j9kg00qf 2360 1 Mandibular mandibular JJ cord-022526-j9kg00qf 2360 2 fistulae fistula NNS cord-022526-j9kg00qf 2360 3 frequently frequently RB cord-022526-j9kg00qf 2360 4 are be VBP cord-022526-j9kg00qf 2360 5 caused cause VBN cord-022526-j9kg00qf 2360 6 by by IN cord-022526-j9kg00qf 2360 7 lower low JJR cord-022526-j9kg00qf 2360 8 cheek cheek NN cord-022526-j9kg00qf 2360 9 tooth tooth NN cord-022526-j9kg00qf 2360 10 apical apical JJ cord-022526-j9kg00qf 2360 11 infections infection NNS cord-022526-j9kg00qf 2360 12 . . . cord-022526-j9kg00qf 2361 1 Some some DT cord-022526-j9kg00qf 2361 2 correlation correlation NN cord-022526-j9kg00qf 2361 3 exists exist VBZ cord-022526-j9kg00qf 2361 4 between between IN cord-022526-j9kg00qf 2361 5 the the DT cord-022526-j9kg00qf 2361 6 age age NN cord-022526-j9kg00qf 2361 7 of of IN cord-022526-j9kg00qf 2361 8 the the DT cord-022526-j9kg00qf 2361 9 animal animal NN cord-022526-j9kg00qf 2361 10 and and CC cord-022526-j9kg00qf 2361 11 clinical clinical JJ cord-022526-j9kg00qf 2361 12 signs sign NNS cord-022526-j9kg00qf 2361 13 ( ( -LRB- cord-022526-j9kg00qf 2361 14 Table table NN cord-022526-j9kg00qf 2361 15 13 13 CD cord-022526-j9kg00qf 2361 16 .8 .8 CD cord-022526-j9kg00qf 2361 17 - - SYM cord-022526-j9kg00qf 2361 18 1 1 CD cord-022526-j9kg00qf 2361 19 ) ) -RRB- cord-022526-j9kg00qf 2361 20 . . . cord-022526-j9kg00qf 2362 1 Ancillary ancillary JJ cord-022526-j9kg00qf 2362 2 aids aids NNP cord-022526-j9kg00qf 2362 3 for for IN cord-022526-j9kg00qf 2362 4 a a DT cord-022526-j9kg00qf 2362 5 complete complete JJ cord-022526-j9kg00qf 2362 6 examination examination NN cord-022526-j9kg00qf 2362 7 of of IN cord-022526-j9kg00qf 2362 8 the the DT cord-022526-j9kg00qf 2362 9 oral oral JJ cord-022526-j9kg00qf 2362 10 cavity cavity NN cord-022526-j9kg00qf 2362 11 of of IN cord-022526-j9kg00qf 2362 12 the the DT cord-022526-j9kg00qf 2362 13 horse horse NN cord-022526-j9kg00qf 2362 14 may may MD cord-022526-j9kg00qf 2362 15 include include VB cord-022526-j9kg00qf 2362 16 radiology radiology NN cord-022526-j9kg00qf 2362 17 , , , cord-022526-j9kg00qf 2362 18 endoscopic endoscopic JJ cord-022526-j9kg00qf 2362 19 examination examination NN cord-022526-j9kg00qf 2362 20 , , , cord-022526-j9kg00qf 2362 21 fluoroscopy fluoroscopy NN cord-022526-j9kg00qf 2362 22 , , , cord-022526-j9kg00qf 2362 23 biopsy biopsy NN cord-022526-j9kg00qf 2362 24 , , , cord-022526-j9kg00qf 2362 25 and and CC cord-022526-j9kg00qf 2362 26 culture culture NN cord-022526-j9kg00qf 2362 27 . . . cord-022526-j9kg00qf 2363 1 One one PRP cord-022526-j9kg00qf 2363 2 should should MD cord-022526-j9kg00qf 2363 3 take take VB cord-022526-j9kg00qf 2363 4 care care NN cord-022526-j9kg00qf 2363 5 always always RB cord-022526-j9kg00qf 2363 6 during during IN cord-022526-j9kg00qf 2363 7 endoscopic endoscopic JJ cord-022526-j9kg00qf 2363 8 evaluation evaluation NN cord-022526-j9kg00qf 2363 9 of of IN cord-022526-j9kg00qf 2363 10 the the DT cord-022526-j9kg00qf 2363 11 oral oral JJ cord-022526-j9kg00qf 2363 12 cavity cavity NN cord-022526-j9kg00qf 2363 13 using use VBG cord-022526-j9kg00qf 2363 14 a a DT cord-022526-j9kg00qf 2363 15 flexible flexible JJ cord-022526-j9kg00qf 2363 16 endoscope endoscope NN cord-022526-j9kg00qf 2363 17 . . . cord-022526-j9kg00qf 2364 1 The the DT cord-022526-j9kg00qf 2364 2 author author NN cord-022526-j9kg00qf 2364 3 recommends recommend VBZ cord-022526-j9kg00qf 2364 4 sedation sedation NN cord-022526-j9kg00qf 2364 5 and and CC cord-022526-j9kg00qf 2364 6 the the DT cord-022526-j9kg00qf 2364 7 use use NN cord-022526-j9kg00qf 2364 8 of of IN cord-022526-j9kg00qf 2364 9 an an DT cord-022526-j9kg00qf 2364 10 oral oral JJ cord-022526-j9kg00qf 2364 11 speculum speculum NN cord-022526-j9kg00qf 2364 12 to to TO cord-022526-j9kg00qf 2364 13 prevent prevent VB cord-022526-j9kg00qf 2364 14 inadvertent inadvertent JJ cord-022526-j9kg00qf 2364 15 mastication mastication NN cord-022526-j9kg00qf 2364 16 of of IN cord-022526-j9kg00qf 2364 17 the the DT cord-022526-j9kg00qf 2364 18 endoscope endoscope NN cord-022526-j9kg00qf 2364 19 . . . cord-022526-j9kg00qf 2365 1 If if IN cord-022526-j9kg00qf 2365 2 one one CD cord-022526-j9kg00qf 2365 3 uses use VBZ cord-022526-j9kg00qf 2365 4 general general JJ cord-022526-j9kg00qf 2365 5 anesthesia anesthesia NN cord-022526-j9kg00qf 2365 6 as as IN cord-022526-j9kg00qf 2365 7 part part NN cord-022526-j9kg00qf 2365 8 of of IN cord-022526-j9kg00qf 2365 9 the the DT cord-022526-j9kg00qf 2365 10 diagnostic diagnostic JJ cord-022526-j9kg00qf 2365 11 workup workup NN cord-022526-j9kg00qf 2365 12 , , , cord-022526-j9kg00qf 2365 13 then then RB cord-022526-j9kg00qf 2365 14 endoscopic endoscopic JJ cord-022526-j9kg00qf 2365 15 evaluation evaluation NN cord-022526-j9kg00qf 2365 16 of of IN cord-022526-j9kg00qf 2365 17 the the DT cord-022526-j9kg00qf 2365 18 oral oral JJ cord-022526-j9kg00qf 2365 19 cavity cavity NN cord-022526-j9kg00qf 2365 20 is be VBZ cord-022526-j9kg00qf 2365 21 much much RB cord-022526-j9kg00qf 2365 22 easier easy JJR cord-022526-j9kg00qf 2365 23 . . . cord-022526-j9kg00qf 2366 1 In in IN cord-022526-j9kg00qf 2366 2 selected select VBN cord-022526-j9kg00qf 2366 3 cases case NNS cord-022526-j9kg00qf 2366 4 , , , cord-022526-j9kg00qf 2366 5 advanced advanced JJ cord-022526-j9kg00qf 2366 6 imaging imaging NN cord-022526-j9kg00qf 2366 7 technologies technology NNS cord-022526-j9kg00qf 2366 8 such such JJ cord-022526-j9kg00qf 2366 9 as as IN cord-022526-j9kg00qf 2366 10 computed compute VBN cord-022526-j9kg00qf 2366 11 tomography tomography NN cord-022526-j9kg00qf 2366 12 , , , cord-022526-j9kg00qf 2366 13 magnetic magnetic JJ cord-022526-j9kg00qf 2366 14 resonance resonance NN cord-022526-j9kg00qf 2366 15 imaging imaging NN cord-022526-j9kg00qf 2366 16 , , , cord-022526-j9kg00qf 2366 17 or or CC cord-022526-j9kg00qf 2366 18 nuclear nuclear JJ cord-022526-j9kg00qf 2366 19 scintigraphy scintigraphy NN cord-022526-j9kg00qf 2366 20 may may MD cord-022526-j9kg00qf 2366 21 be be VB cord-022526-j9kg00qf 2366 22 beneficial beneficial JJ cord-022526-j9kg00qf 2366 23 . . . cord-022526-j9kg00qf 2367 1 The the DT cord-022526-j9kg00qf 2367 2 lips lip NNS cord-022526-j9kg00qf 2367 3 of of IN cord-022526-j9kg00qf 2367 4 the the DT cord-022526-j9kg00qf 2367 5 horse horse NN cord-022526-j9kg00qf 2367 6 are be VBP cord-022526-j9kg00qf 2367 7 mobile mobile JJ cord-022526-j9kg00qf 2367 8 and and CC cord-022526-j9kg00qf 2367 9 prehensile prehensile JJ cord-022526-j9kg00qf 2367 10 . . . cord-022526-j9kg00qf 2368 1 In in IN cord-022526-j9kg00qf 2368 2 many many JJ cord-022526-j9kg00qf 2368 3 ways way NNS cord-022526-j9kg00qf 2368 4 they -PRON- PRP cord-022526-j9kg00qf 2368 5 function function VBP cord-022526-j9kg00qf 2368 6 like like IN cord-022526-j9kg00qf 2368 7 the the DT cord-022526-j9kg00qf 2368 8 tip tip NN cord-022526-j9kg00qf 2368 9 of of IN cord-022526-j9kg00qf 2368 10 the the DT cord-022526-j9kg00qf 2368 11 elephant elephant NN cord-022526-j9kg00qf 2368 12 's 's POS cord-022526-j9kg00qf 2368 13 trunk trunk NN cord-022526-j9kg00qf 2368 14 in in IN cord-022526-j9kg00qf 2368 15 that that IN cord-022526-j9kg00qf 2368 16 they -PRON- PRP cord-022526-j9kg00qf 2368 17 test test VBP cord-022526-j9kg00qf 2368 18 , , , cord-022526-j9kg00qf 2368 19 manipulate manipulate VBP cord-022526-j9kg00qf 2368 20 , , , cord-022526-j9kg00qf 2368 21 and and CC cord-022526-j9kg00qf 2368 22 sample sample VB cord-022526-j9kg00qf 2368 23 the the DT cord-022526-j9kg00qf 2368 24 environment environment NN cord-022526-j9kg00qf 2368 25 for for IN cord-022526-j9kg00qf 2368 26 potential potential JJ cord-022526-j9kg00qf 2368 27 nutritive nutritive JJ cord-022526-j9kg00qf 2368 28 value value NN cord-022526-j9kg00qf 2368 29 . . . cord-022526-j9kg00qf 2369 1 Consequently consequently RB cord-022526-j9kg00qf 2369 2 , , , cord-022526-j9kg00qf 2369 3 loss loss NN cord-022526-j9kg00qf 2369 4 of of IN cord-022526-j9kg00qf 2369 5 motor motor NN cord-022526-j9kg00qf 2369 6 function function NN cord-022526-j9kg00qf 2369 7 ( ( -LRB- cord-022526-j9kg00qf 2369 8 e.g. e.g. RB cord-022526-j9kg00qf 2369 9 , , , cord-022526-j9kg00qf 2369 10 facial facial JJ cord-022526-j9kg00qf 2369 11 palsy palsy NN cord-022526-j9kg00qf 2369 12 ) ) -RRB- cord-022526-j9kg00qf 2369 13 affects affect VBZ cord-022526-j9kg00qf 2369 14 the the DT cord-022526-j9kg00qf 2369 15 efficiency efficiency NN cord-022526-j9kg00qf 2369 16 of of IN cord-022526-j9kg00qf 2369 17 the the DT cord-022526-j9kg00qf 2369 18 prehensile prehensile JJ cord-022526-j9kg00qf 2369 19 system system NN cord-022526-j9kg00qf 2369 20 . . . cord-022526-j9kg00qf 2370 1 The the DT cord-022526-j9kg00qf 2370 2 lips lip NNS cord-022526-j9kg00qf 2370 3 grasp grasp VBP cord-022526-j9kg00qf 2370 4 food food NN cord-022526-j9kg00qf 2370 5 in in IN cord-022526-j9kg00qf 2370 6 grazing grazing NN cord-022526-j9kg00qf 2370 7 or or CC cord-022526-j9kg00qf 2370 8 browsing browsing NN cord-022526-j9kg00qf 2370 9 , , , cord-022526-j9kg00qf 2370 10 and and CC cord-022526-j9kg00qf 2370 11 the the DT cord-022526-j9kg00qf 2370 12 incisor incisor NN cord-022526-j9kg00qf 2370 13 teeth tooth NNS cord-022526-j9kg00qf 2370 14 section section VBP cord-022526-j9kg00qf 2370 15 the the DT cord-022526-j9kg00qf 2370 16 food food NN cord-022526-j9kg00qf 2370 17 . . . cord-022526-j9kg00qf 2371 1 With with IN cord-022526-j9kg00qf 2371 2 mastication mastication NN cord-022526-j9kg00qf 2371 3 and and CC cord-022526-j9kg00qf 2371 4 lubrication lubrication NN cord-022526-j9kg00qf 2371 5 with with IN cord-022526-j9kg00qf 2371 6 saliva saliva NN cord-022526-j9kg00qf 2371 7 , , , cord-022526-j9kg00qf 2371 8 the the DT cord-022526-j9kg00qf 2371 9 bolus bolus NN cord-022526-j9kg00qf 2371 10 of of IN cord-022526-j9kg00qf 2371 11 food food NN cord-022526-j9kg00qf 2371 12 forms form NNS cord-022526-j9kg00qf 2371 13 and and CC cord-022526-j9kg00qf 2371 14 is be VBZ cord-022526-j9kg00qf 2371 15 manipulated manipulate VBN cord-022526-j9kg00qf 2371 16 from from IN cord-022526-j9kg00qf 2371 17 side side NN cord-022526-j9kg00qf 2371 18 to to TO cord-022526-j9kg00qf 2371 19 side side VB cord-022526-j9kg00qf 2371 20 across across IN cord-022526-j9kg00qf 2371 21 the the DT cord-022526-j9kg00qf 2371 22 mouth mouth NN cord-022526-j9kg00qf 2371 23 , , , cord-022526-j9kg00qf 2371 24 assisted assist VBN cord-022526-j9kg00qf 2371 25 by by IN cord-022526-j9kg00qf 2371 26 the the DT cord-022526-j9kg00qf 2371 27 tight tight JJ cord-022526-j9kg00qf 2371 28 cheeks cheek NNS cord-022526-j9kg00qf 2371 29 of of IN cord-022526-j9kg00qf 2371 30 the the DT cord-022526-j9kg00qf 2371 31 horse horse NN cord-022526-j9kg00qf 2371 32 and and CC cord-022526-j9kg00qf 2371 33 the the DT cord-022526-j9kg00qf 2371 34 palatine palatine NNP cord-022526-j9kg00qf 2371 35 ridges ridge NNS cord-022526-j9kg00qf 2371 36 . . . cord-022526-j9kg00qf 2372 1 Swallowing swallowing NN cord-022526-j9kg00qf 2372 2 begins begin VBZ cord-022526-j9kg00qf 2372 3 as as IN cord-022526-j9kg00qf 2372 4 the the DT cord-022526-j9kg00qf 2372 5 food food NN cord-022526-j9kg00qf 2372 6 bolus bolus NN cord-022526-j9kg00qf 2372 7 contacts contact VBZ cord-022526-j9kg00qf 2372 8 the the DT cord-022526-j9kg00qf 2372 9 base base NN cord-022526-j9kg00qf 2372 10 of of IN cord-022526-j9kg00qf 2372 11 the the DT cord-022526-j9kg00qf 2372 12 tongue tongue NN cord-022526-j9kg00qf 2372 13 and and CC cord-022526-j9kg00qf 2372 14 the the DT cord-022526-j9kg00qf 2372 15 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2372 16 walls wall NNS cord-022526-j9kg00qf 2372 17 . . . cord-022526-j9kg00qf 2373 1 During during IN cord-022526-j9kg00qf 2373 2 swallowing swallow VBG cord-022526-j9kg00qf 2373 3 , , , cord-022526-j9kg00qf 2373 4 the the DT cord-022526-j9kg00qf 2373 5 soft soft JJ cord-022526-j9kg00qf 2373 6 palate palate NN cord-022526-j9kg00qf 2373 7 elevates elevate VBZ cord-022526-j9kg00qf 2373 8 to to TO cord-022526-j9kg00qf 2373 9 close close VB cord-022526-j9kg00qf 2373 10 the the DT cord-022526-j9kg00qf 2373 11 nasopharynx nasopharynx NN cord-022526-j9kg00qf 2373 12 , , , cord-022526-j9kg00qf 2373 13 the the DT cord-022526-j9kg00qf 2373 14 base base NN cord-022526-j9kg00qf 2373 15 of of IN cord-022526-j9kg00qf 2373 16 the the DT cord-022526-j9kg00qf 2373 17 tongue tongue NN cord-022526-j9kg00qf 2373 18 elevates elevate VBZ cord-022526-j9kg00qf 2373 19 , , , cord-022526-j9kg00qf 2373 20 and and CC cord-022526-j9kg00qf 2373 21 the the DT cord-022526-j9kg00qf 2373 22 hyoid hyoid NN cord-022526-j9kg00qf 2373 23 bone bone NN cord-022526-j9kg00qf 2373 24 and and CC cord-022526-j9kg00qf 2373 25 the the DT cord-022526-j9kg00qf 2373 26 larynx larynx NN cord-022526-j9kg00qf 2373 27 move move NN cord-022526-j9kg00qf 2373 28 rostrally rostrally RB cord-022526-j9kg00qf 2373 29 following follow VBG cord-022526-j9kg00qf 2373 30 contraction contraction NN cord-022526-j9kg00qf 2373 31 of of IN cord-022526-j9kg00qf 2373 32 the the DT cord-022526-j9kg00qf 2373 33 hyoid hyoid NN cord-022526-j9kg00qf 2373 34 muscles muscle NNS cord-022526-j9kg00qf 2373 35 . . . cord-022526-j9kg00qf 2374 1 During during IN cord-022526-j9kg00qf 2374 2 this this DT cord-022526-j9kg00qf 2374 3 process process NN cord-022526-j9kg00qf 2374 4 , , , cord-022526-j9kg00qf 2374 5 the the DT cord-022526-j9kg00qf 2374 6 rima rima NNP cord-022526-j9kg00qf 2374 7 glottidis glottidis NNP cord-022526-j9kg00qf 2374 8 closes close VBZ cord-022526-j9kg00qf 2374 9 and and CC cord-022526-j9kg00qf 2374 10 the the DT cord-022526-j9kg00qf 2374 11 epiglottis epiglottis NN cord-022526-j9kg00qf 2374 12 tilts tilt VBZ cord-022526-j9kg00qf 2374 13 dorsally dorsally RB cord-022526-j9kg00qf 2374 14 and and CC cord-022526-j9kg00qf 2374 15 caudally caudally RB cord-022526-j9kg00qf 2374 16 to to TO cord-022526-j9kg00qf 2374 17 protect protect VB cord-022526-j9kg00qf 2374 18 the the DT cord-022526-j9kg00qf 2374 19 airway airway NN cord-022526-j9kg00qf 2374 20 so so IN cord-022526-j9kg00qf 2374 21 that that IN cord-022526-j9kg00qf 2374 22 food food NN cord-022526-j9kg00qf 2374 23 is be VBZ cord-022526-j9kg00qf 2374 24 swept sweep VBN cord-022526-j9kg00qf 2374 25 through through IN cord-022526-j9kg00qf 2374 26 lateral lateral JJ cord-022526-j9kg00qf 2374 27 food food NN cord-022526-j9kg00qf 2374 28 channels channel NNS cord-022526-j9kg00qf 2374 29 around around IN cord-022526-j9kg00qf 2374 30 the the DT cord-022526-j9kg00qf 2374 31 sides side NNS cord-022526-j9kg00qf 2374 32 of of IN cord-022526-j9kg00qf 2374 33 the the DT cord-022526-j9kg00qf 2374 34 larynx larynx NN cord-022526-j9kg00qf 2374 35 into into IN cord-022526-j9kg00qf 2374 36 the the DT cord-022526-j9kg00qf 2374 37 laryngoesophagus laryngoesophagus NNP cord-022526-j9kg00qf 2374 38 . . . cord-022526-j9kg00qf 2375 1 Fluoroscopic Fluoroscopic NNP cord-022526-j9kg00qf 2375 2 studies study NNS cord-022526-j9kg00qf 2375 3 in in IN cord-022526-j9kg00qf 2375 4 nursing nursing NN cord-022526-j9kg00qf 2375 5 foals foal NNS cord-022526-j9kg00qf 2375 6 in in IN cord-022526-j9kg00qf 2375 7 the the DT cord-022526-j9kg00qf 2375 8 dorsoventral dorsoventral JJ cord-022526-j9kg00qf 2375 9 view view NN cord-022526-j9kg00qf 2375 10 showed show VBD cord-022526-j9kg00qf 2375 11 that that IN cord-022526-j9kg00qf 2375 12 contact contact NN cord-022526-j9kg00qf 2375 13 occurs occur VBZ cord-022526-j9kg00qf 2375 14 between between IN cord-022526-j9kg00qf 2375 15 the the DT cord-022526-j9kg00qf 2375 16 lateral lateral JJ cord-022526-j9kg00qf 2375 17 food food NN cord-022526-j9kg00qf 2375 18 channels channel NNS cord-022526-j9kg00qf 2375 19 in in IN cord-022526-j9kg00qf 2375 20 the the DT cord-022526-j9kg00qf 2375 21 midline midline NN cord-022526-j9kg00qf 2375 22 so so IN cord-022526-j9kg00qf 2375 23 that that IN cord-022526-j9kg00qf 2375 24 in in IN cord-022526-j9kg00qf 2375 25 outline outline NN cord-022526-j9kg00qf 2375 26 the the DT cord-022526-j9kg00qf 2375 27 food food NN cord-022526-j9kg00qf 2375 28 bolus bolus NN cord-022526-j9kg00qf 2375 29 achieves achieve VBZ cord-022526-j9kg00qf 2375 30 a a DT cord-022526-j9kg00qf 2375 31 bow bow NN cord-022526-j9kg00qf 2375 32 tie tie NN cord-022526-j9kg00qf 2375 33 shape shape NN cord-022526-j9kg00qf 2375 34 . . . cord-022526-j9kg00qf 2376 1 4 4 LS cord-022526-j9kg00qf 2376 2 Dysphagia Dysphagia NNP cord-022526-j9kg00qf 2376 3 is be VBZ cord-022526-j9kg00qf 2376 4 defined define VBN cord-022526-j9kg00qf 2376 5 as as IN cord-022526-j9kg00qf 2376 6 a a DT cord-022526-j9kg00qf 2376 7 difficulty difficulty NN cord-022526-j9kg00qf 2376 8 or or CC cord-022526-j9kg00qf 2376 9 inability inability NN cord-022526-j9kg00qf 2376 10 to to TO cord-022526-j9kg00qf 2376 11 swallow swallow VB cord-022526-j9kg00qf 2376 12 . . . cord-022526-j9kg00qf 2377 1 Anatomic anatomic JJ cord-022526-j9kg00qf 2377 2 classifications classification NNS cord-022526-j9kg00qf 2377 3 for for IN cord-022526-j9kg00qf 2377 4 dysphagia dysphagia NN cord-022526-j9kg00qf 2377 5 include include VBP cord-022526-j9kg00qf 2377 6 prepharyngeal prepharyngeal NN cord-022526-j9kg00qf 2377 7 , , , cord-022526-j9kg00qf 2377 8 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2377 9 , , , cord-022526-j9kg00qf 2377 10 and and CC cord-022526-j9kg00qf 2377 11 esophageal esophageal JJ cord-022526-j9kg00qf 2377 12 ( ( -LRB- cord-022526-j9kg00qf 2377 13 postpharyngeal postpharyngeal NNP cord-022526-j9kg00qf 2377 14 ) ) -RRB- cord-022526-j9kg00qf 2377 15 dysphagias dysphagias NNP cord-022526-j9kg00qf 2377 16 . . . cord-022526-j9kg00qf 2378 1 The the DT cord-022526-j9kg00qf 2378 2 site site NN cord-022526-j9kg00qf 2378 3 of of IN cord-022526-j9kg00qf 2378 4 the the DT cord-022526-j9kg00qf 2378 5 cause cause NN cord-022526-j9kg00qf 2378 6 for for IN cord-022526-j9kg00qf 2378 7 dysphagia dysphagia NN cord-022526-j9kg00qf 2378 8 influences influence VBZ cord-022526-j9kg00qf 2378 9 the the DT cord-022526-j9kg00qf 2378 10 clinical clinical JJ cord-022526-j9kg00qf 2378 11 signs sign NNS cord-022526-j9kg00qf 2378 12 . . . cord-022526-j9kg00qf 2379 1 Prepharyngeal prepharyngeal NN cord-022526-j9kg00qf 2379 2 dysphagia dysphagia NN cord-022526-j9kg00qf 2379 3 is be VBZ cord-022526-j9kg00qf 2379 4 characterized characterize VBN cord-022526-j9kg00qf 2379 5 by by IN cord-022526-j9kg00qf 2379 6 dropping drop VBG cord-022526-j9kg00qf 2379 7 food food NN cord-022526-j9kg00qf 2379 8 ( ( -LRB- cord-022526-j9kg00qf 2379 9 quidding quidding NNP cord-022526-j9kg00qf 2379 10 ) ) -RRB- cord-022526-j9kg00qf 2379 11 or or CC cord-022526-j9kg00qf 2379 12 water water NN cord-022526-j9kg00qf 2379 13 from from IN cord-022526-j9kg00qf 2379 14 the the DT cord-022526-j9kg00qf 2379 15 mouth mouth NN cord-022526-j9kg00qf 2379 16 , , , cord-022526-j9kg00qf 2379 17 reluctance reluctance NN cord-022526-j9kg00qf 2379 18 to to TO cord-022526-j9kg00qf 2379 19 chew chew VB cord-022526-j9kg00qf 2379 20 , , , cord-022526-j9kg00qf 2379 21 hypersalivation hypersalivation NN cord-022526-j9kg00qf 2379 22 , , , cord-022526-j9kg00qf 2379 23 or or CC cord-022526-j9kg00qf 2379 24 abnormalities abnormality NNS cord-022526-j9kg00qf 2379 25 in in IN cord-022526-j9kg00qf 2379 26 prehension prehension NN cord-022526-j9kg00qf 2379 27 . . . cord-022526-j9kg00qf 2380 1 Pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2380 2 and and CC cord-022526-j9kg00qf 2380 3 esophageal esophageal JJ cord-022526-j9kg00qf 2380 4 dysphagias dysphagia NNS cord-022526-j9kg00qf 2380 5 are be VBP cord-022526-j9kg00qf 2380 6 characterized characterize VBN cord-022526-j9kg00qf 2380 7 by by IN cord-022526-j9kg00qf 2380 8 coughing cough VBG cord-022526-j9kg00qf 2380 9 ; ; : cord-022526-j9kg00qf 2380 10 nasal nasal NN cord-022526-j9kg00qf 2380 11 discharge discharge NN cord-022526-j9kg00qf 2380 12 containing contain VBG cord-022526-j9kg00qf 2380 13 saliva saliva NN cord-022526-j9kg00qf 2380 14 , , , cord-022526-j9kg00qf 2380 15 water water NN cord-022526-j9kg00qf 2380 16 , , , cord-022526-j9kg00qf 2380 17 or or CC cord-022526-j9kg00qf 2380 18 food food NN cord-022526-j9kg00qf 2380 19 material material NN cord-022526-j9kg00qf 2380 20 ; ; : cord-022526-j9kg00qf 2380 21 gagging gagging NN cord-022526-j9kg00qf 2380 22 ; ; : cord-022526-j9kg00qf 2380 23 anxiousness anxiousness NN cord-022526-j9kg00qf 2380 24 ; ; : cord-022526-j9kg00qf 2380 25 and and CC cord-022526-j9kg00qf 2380 26 neck neck NN cord-022526-j9kg00qf 2380 27 extension extension NN cord-022526-j9kg00qf 2380 28 during during IN cord-022526-j9kg00qf 2380 29 attempts attempt NNS cord-022526-j9kg00qf 2380 30 to to TO cord-022526-j9kg00qf 2380 31 swallow swallow VB cord-022526-j9kg00qf 2380 32 . . . cord-022526-j9kg00qf 2381 1 The the DT cord-022526-j9kg00qf 2381 2 following following JJ cord-022526-j9kg00qf 2381 3 section section NN cord-022526-j9kg00qf 2381 4 describes describe VBZ cord-022526-j9kg00qf 2381 5 esophageal esophageal JJ cord-022526-j9kg00qf 2381 6 dysphagia dysphagia NN cord-022526-j9kg00qf 2381 7 in in IN cord-022526-j9kg00qf 2381 8 more more JJR cord-022526-j9kg00qf 2381 9 detail detail NN cord-022526-j9kg00qf 2381 10 . . . cord-022526-j9kg00qf 2382 1 Causes cause NNS cord-022526-j9kg00qf 2382 2 of of IN cord-022526-j9kg00qf 2382 3 dysphagia dysphagia NN cord-022526-j9kg00qf 2382 4 can can MD cord-022526-j9kg00qf 2382 5 be be VB cord-022526-j9kg00qf 2382 6 divided divide VBN cord-022526-j9kg00qf 2382 7 into into IN cord-022526-j9kg00qf 2382 8 four four CD cord-022526-j9kg00qf 2382 9 types type NNS cord-022526-j9kg00qf 2382 10 : : : cord-022526-j9kg00qf 2382 11 painful painful JJ cord-022526-j9kg00qf 2382 12 , , , cord-022526-j9kg00qf 2382 13 muscular muscular JJ cord-022526-j9kg00qf 2382 14 , , , cord-022526-j9kg00qf 2382 15 neurologic neurologic JJ cord-022526-j9kg00qf 2382 16 , , , cord-022526-j9kg00qf 2382 17 or or CC cord-022526-j9kg00qf 2382 18 obstructive obstructive JJ cord-022526-j9kg00qf 2382 19 ( ( -LRB- cord-022526-j9kg00qf 2382 20 Table table NN cord-022526-j9kg00qf 2382 21 13 13 CD cord-022526-j9kg00qf 2382 22 .8 .8 CD cord-022526-j9kg00qf 2382 23 - - SYM cord-022526-j9kg00qf 2382 24 2 2 CD cord-022526-j9kg00qf 2382 25 ) ) -RRB- cord-022526-j9kg00qf 2382 26 . . . cord-022526-j9kg00qf 2383 1 Pain pain NN cord-022526-j9kg00qf 2383 2 and and CC cord-022526-j9kg00qf 2383 3 obstruction obstruction NN cord-022526-j9kg00qf 2383 4 cause cause NN cord-022526-j9kg00qf 2383 5 dysphagia dysphagia NN cord-022526-j9kg00qf 2383 6 by by IN cord-022526-j9kg00qf 2383 7 interfering interfere VBG cord-022526-j9kg00qf 2383 8 with with IN cord-022526-j9kg00qf 2383 9 the the DT cord-022526-j9kg00qf 2383 10 mechanics mechanic NNS cord-022526-j9kg00qf 2383 11 of of IN cord-022526-j9kg00qf 2383 12 prehension prehension NN cord-022526-j9kg00qf 2383 13 , , , cord-022526-j9kg00qf 2383 14 bolus bolus NN cord-022526-j9kg00qf 2383 15 formation formation NN cord-022526-j9kg00qf 2383 16 and and CC cord-022526-j9kg00qf 2383 17 transfer transfer VB cord-022526-j9kg00qf 2383 18 to to IN cord-022526-j9kg00qf 2383 19 the the DT cord-022526-j9kg00qf 2383 20 pharynx pharynx NN cord-022526-j9kg00qf 2383 21 , , , cord-022526-j9kg00qf 2383 22 and and CC cord-022526-j9kg00qf 2383 23 deglutition deglutition NN cord-022526-j9kg00qf 2383 24 . . . cord-022526-j9kg00qf 2384 1 Muscular muscular JJ cord-022526-j9kg00qf 2384 2 and and CC cord-022526-j9kg00qf 2384 3 neurologic neurologic JJ cord-022526-j9kg00qf 2384 4 causes cause NNS cord-022526-j9kg00qf 2384 5 of of IN cord-022526-j9kg00qf 2384 6 dysphagia dysphagia NN cord-022526-j9kg00qf 2384 7 impede impede VB cord-022526-j9kg00qf 2384 8 prehension prehension NN cord-022526-j9kg00qf 2384 9 and and CC cord-022526-j9kg00qf 2384 10 swallowing swallowing NN cord-022526-j9kg00qf 2384 11 by by IN cord-022526-j9kg00qf 2384 12 affecting affect VBG cord-022526-j9kg00qf 2384 13 the the DT cord-022526-j9kg00qf 2384 14 motor motor NN cord-022526-j9kg00qf 2384 15 function function NN cord-022526-j9kg00qf 2384 16 of of IN cord-022526-j9kg00qf 2384 17 the the DT cord-022526-j9kg00qf 2384 18 lingual lingual JJ cord-022526-j9kg00qf 2384 19 or or CC cord-022526-j9kg00qf 2384 20 buccal buccal JJ cord-022526-j9kg00qf 2384 21 musculature musculature NN cord-022526-j9kg00qf 2384 22 , , , cord-022526-j9kg00qf 2384 23 muscles muscle NNS cord-022526-j9kg00qf 2384 24 of of IN cord-022526-j9kg00qf 2384 25 mastication mastication NN cord-022526-j9kg00qf 2384 26 ( ( -LRB- cord-022526-j9kg00qf 2384 27 temporal temporal JJ cord-022526-j9kg00qf 2384 28 and and CC cord-022526-j9kg00qf 2384 29 masseters masseter NNS cord-022526-j9kg00qf 2384 30 ) ) -RRB- cord-022526-j9kg00qf 2384 31 , , , cord-022526-j9kg00qf 2384 32 and and CC cord-022526-j9kg00qf 2384 33 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2384 34 and and CC cord-022526-j9kg00qf 2384 35 cranial cranial JJ cord-022526-j9kg00qf 2384 36 esophageal esophageal JJ cord-022526-j9kg00qf 2384 37 muscles muscle NNS cord-022526-j9kg00qf 2384 38 . . . cord-022526-j9kg00qf 2385 1 Sensory sensory JJ cord-022526-j9kg00qf 2385 2 loss loss NN cord-022526-j9kg00qf 2385 3 to to IN cord-022526-j9kg00qf 2385 4 the the DT cord-022526-j9kg00qf 2385 5 lips lip NNS cord-022526-j9kg00qf 2385 6 , , , cord-022526-j9kg00qf 2385 7 buccal buccal JJ cord-022526-j9kg00qf 2385 8 mucous mucous JJ cord-022526-j9kg00qf 2385 9 membranes membrane NNS cord-022526-j9kg00qf 2385 10 , , , cord-022526-j9kg00qf 2385 11 pharynx pharynx NN cord-022526-j9kg00qf 2385 12 , , , cord-022526-j9kg00qf 2385 13 or or CC cord-022526-j9kg00qf 2385 14 tongue tongue NN cord-022526-j9kg00qf 2385 15 also also RB cord-022526-j9kg00qf 2385 16 may may MD cord-022526-j9kg00qf 2385 17 cause cause VB cord-022526-j9kg00qf 2385 18 dysphagia dysphagia NN cord-022526-j9kg00qf 2385 19 . . . cord-022526-j9kg00qf 2386 1 Neurologic neurologic JJ cord-022526-j9kg00qf 2386 2 causes cause NNS cord-022526-j9kg00qf 2386 3 of of IN cord-022526-j9kg00qf 2386 4 dysphagia dysphagia NN cord-022526-j9kg00qf 2386 5 may may MD cord-022526-j9kg00qf 2386 6 affect affect VB cord-022526-j9kg00qf 2386 7 the the DT cord-022526-j9kg00qf 2386 8 forebrain forebrain NN cord-022526-j9kg00qf 2386 9 , , , cord-022526-j9kg00qf 2386 10 brainstem brainstem NN cord-022526-j9kg00qf 2386 11 , , , cord-022526-j9kg00qf 2386 12 or or CC cord-022526-j9kg00qf 2386 13 peripheral peripheral JJ cord-022526-j9kg00qf 2386 14 nerves nerve NNS cord-022526-j9kg00qf 2386 15 that that WDT cord-022526-j9kg00qf 2386 16 control control VBP cord-022526-j9kg00qf 2386 17 prehension prehension NN cord-022526-j9kg00qf 2386 18 ( ( -LRB- cord-022526-j9kg00qf 2386 19 cranial cranial JJ cord-022526-j9kg00qf 2386 20 nerves nerve NNS cord-022526-j9kg00qf 2386 21 Vm Vm NNP cord-022526-j9kg00qf 2386 22 , , , cord-022526-j9kg00qf 2386 23 Vs Vs NNP cord-022526-j9kg00qf 2386 24 , , , cord-022526-j9kg00qf 2386 25 VII VII NNP cord-022526-j9kg00qf 2386 26 , , , cord-022526-j9kg00qf 2386 27 and and CC cord-022526-j9kg00qf 2386 28 XII XII NNP cord-022526-j9kg00qf 2386 29 ) ) -RRB- cord-022526-j9kg00qf 2386 30 , , , cord-022526-j9kg00qf 2386 31 transfer transfer NN cord-022526-j9kg00qf 2386 32 of of IN cord-022526-j9kg00qf 2386 33 the the DT cord-022526-j9kg00qf 2386 34 food food NN cord-022526-j9kg00qf 2386 35 bolus bolus NN cord-022526-j9kg00qf 2386 36 to to IN cord-022526-j9kg00qf 2386 37 the the DT cord-022526-j9kg00qf 2386 38 pharynx pharynx NN cord-022526-j9kg00qf 2386 39 ( ( -LRB- cord-022526-j9kg00qf 2386 40 cranial cranial JJ cord-022526-j9kg00qf 2386 41 nerves nerve NNS cord-022526-j9kg00qf 2386 42 Vs Vs NNP cord-022526-j9kg00qf 2386 43 and and CC cord-022526-j9kg00qf 2386 44 XII XII NNP cord-022526-j9kg00qf 2386 45 ) ) -RRB- cord-022526-j9kg00qf 2386 46 and and CC cord-022526-j9kg00qf 2386 47 swallowing swallow VBG cord-022526-j9kg00qf 2386 48 ( ( -LRB- cord-022526-j9kg00qf 2386 49 cranial cranial JJ cord-022526-j9kg00qf 2386 50 nerves nerve NNS cord-022526-j9kg00qf 2386 51 IX IX NNP cord-022526-j9kg00qf 2386 52 and and CC cord-022526-j9kg00qf 2386 53 X X NNP cord-022526-j9kg00qf 2386 54 ) ) -RRB- cord-022526-j9kg00qf 2386 55 . . . cord-022526-j9kg00qf 2387 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 2387 2 of of IN cord-022526-j9kg00qf 2387 3 the the DT cord-022526-j9kg00qf 2387 4 cause cause NN cord-022526-j9kg00qf 2387 5 of of IN cord-022526-j9kg00qf 2387 6 dysphagia dysphagia NN cord-022526-j9kg00qf 2387 7 is be VBZ cord-022526-j9kg00qf 2387 8 based base VBN cord-022526-j9kg00qf 2387 9 on on IN cord-022526-j9kg00qf 2387 10 physical physical JJ cord-022526-j9kg00qf 2387 11 examination examination NN cord-022526-j9kg00qf 2387 12 including include VBG cord-022526-j9kg00qf 2387 13 a a DT cord-022526-j9kg00qf 2387 14 careful careful JJ cord-022526-j9kg00qf 2387 15 oral oral JJ cord-022526-j9kg00qf 2387 16 examination examination NN cord-022526-j9kg00qf 2387 17 , , , cord-022526-j9kg00qf 2387 18 neurologic neurologic JJ cord-022526-j9kg00qf 2387 19 examination examination NN cord-022526-j9kg00qf 2387 20 , , , cord-022526-j9kg00qf 2387 21 clinical clinical JJ cord-022526-j9kg00qf 2387 22 signs sign NNS cord-022526-j9kg00qf 2387 23 , , , cord-022526-j9kg00qf 2387 24 and and CC cord-022526-j9kg00qf 2387 25 endoscopy endoscopy NN cord-022526-j9kg00qf 2387 26 of of IN cord-022526-j9kg00qf 2387 27 the the DT cord-022526-j9kg00qf 2387 28 pharynx pharynx NN cord-022526-j9kg00qf 2387 29 , , , cord-022526-j9kg00qf 2387 30 esophagus esophagus NN cord-022526-j9kg00qf 2387 31 , , , cord-022526-j9kg00qf 2387 32 and and CC cord-022526-j9kg00qf 2387 33 guttural guttural JJ cord-022526-j9kg00qf 2387 34 pouches pouch NNS cord-022526-j9kg00qf 2387 35 . . . cord-022526-j9kg00qf 2388 1 Radiology Radiology NNP cord-022526-j9kg00qf 2388 2 may may MD cord-022526-j9kg00qf 2388 3 be be VB cord-022526-j9kg00qf 2388 4 useful useful JJ cord-022526-j9kg00qf 2388 5 to to TO cord-022526-j9kg00qf 2388 6 assess assess VB cord-022526-j9kg00qf 2388 7 the the DT cord-022526-j9kg00qf 2388 8 bony bony JJ cord-022526-j9kg00qf 2388 9 structures structure NNS cord-022526-j9kg00qf 2388 10 of of IN cord-022526-j9kg00qf 2388 11 the the DT cord-022526-j9kg00qf 2388 12 head head NN cord-022526-j9kg00qf 2388 13 and and CC cord-022526-j9kg00qf 2388 14 throat throat NN cord-022526-j9kg00qf 2388 15 . . . cord-022526-j9kg00qf 2389 1 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 2389 2 is be VBZ cord-022526-j9kg00qf 2389 3 valuable valuable JJ cord-022526-j9kg00qf 2389 4 for for IN cord-022526-j9kg00qf 2389 5 examining examine VBG cord-022526-j9kg00qf 2389 6 the the DT cord-022526-j9kg00qf 2389 7 retropharyngeal retropharyngeal NN cord-022526-j9kg00qf 2389 8 space space NN cord-022526-j9kg00qf 2389 9 and and CC cord-022526-j9kg00qf 2389 10 esophagus esophagus NN cord-022526-j9kg00qf 2389 11 to to TO cord-022526-j9kg00qf 2389 12 detect detect VB cord-022526-j9kg00qf 2389 13 and and CC cord-022526-j9kg00qf 2389 14 evaluate evaluate VB cord-022526-j9kg00qf 2389 15 masses masse NNS cord-022526-j9kg00qf 2389 16 . . . cord-022526-j9kg00qf 2390 1 One one PRP cord-022526-j9kg00qf 2390 2 may may MD cord-022526-j9kg00qf 2390 3 detect detect VB cord-022526-j9kg00qf 2390 4 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2390 5 or or CC cord-022526-j9kg00qf 2390 6 esophageal esophageal JJ cord-022526-j9kg00qf 2390 7 causes cause NNS cord-022526-j9kg00qf 2390 8 of of IN cord-022526-j9kg00qf 2390 9 dysphagia dysphagia NN cord-022526-j9kg00qf 2390 10 with with IN cord-022526-j9kg00qf 2390 11 routine routine JJ cord-022526-j9kg00qf 2390 12 endoscopic endoscopic JJ cord-022526-j9kg00qf 2390 13 examination examination NN cord-022526-j9kg00qf 2390 14 or or CC cord-022526-j9kg00qf 2390 15 with with IN cord-022526-j9kg00qf 2390 16 contrast contrast NN cord-022526-j9kg00qf 2390 17 radiography radiography NN cord-022526-j9kg00qf 2390 18 . . . cord-022526-j9kg00qf 2391 1 Although although IN cord-022526-j9kg00qf 2391 2 one one PRP cord-022526-j9kg00qf 2391 3 also also RB cord-022526-j9kg00qf 2391 4 can can MD cord-022526-j9kg00qf 2391 5 use use VB cord-022526-j9kg00qf 2391 6 endoscopy endoscopy NN cord-022526-j9kg00qf 2391 7 to to TO cord-022526-j9kg00qf 2391 8 assess assess VB cord-022526-j9kg00qf 2391 9 deglutition deglutition NN cord-022526-j9kg00qf 2391 10 , , , cord-022526-j9kg00qf 2391 11 one one PRP cord-022526-j9kg00qf 2391 12 must must MD cord-022526-j9kg00qf 2391 13 remember remember VB cord-022526-j9kg00qf 2391 14 that that IN cord-022526-j9kg00qf 2391 15 sedation sedation NN cord-022526-j9kg00qf 2391 16 adversely adversely RB cord-022526-j9kg00qf 2391 17 affects affect VBZ cord-022526-j9kg00qf 2391 18 the the DT cord-022526-j9kg00qf 2391 19 deglutition deglutition NN cord-022526-j9kg00qf 2391 20 mechanism mechanism NN cord-022526-j9kg00qf 2391 21 . . . cord-022526-j9kg00qf 2392 1 One one CD cord-022526-j9kg00qf 2392 2 may may MD cord-022526-j9kg00qf 2392 3 assess assess VB cord-022526-j9kg00qf 2392 4 deglutition deglutition NN cord-022526-j9kg00qf 2392 5 using use VBG cord-022526-j9kg00qf 2392 6 fluoroscopy fluoroscopy NN cord-022526-j9kg00qf 2392 7 4 4 CD cord-022526-j9kg00qf 2392 8 or or CC cord-022526-j9kg00qf 2392 9 manometry manometry NNP cord-022526-j9kg00qf 2392 10 , , , cord-022526-j9kg00qf 2392 11 5 5 CD cord-022526-j9kg00qf 2392 12 but but CC cord-022526-j9kg00qf 2392 13 these these DT cord-022526-j9kg00qf 2392 14 techniques technique NNS cord-022526-j9kg00qf 2392 15 require require VBP cord-022526-j9kg00qf 2392 16 specialized specialized JJ cord-022526-j9kg00qf 2392 17 equipment equipment NN cord-022526-j9kg00qf 2392 18 . . . cord-022526-j9kg00qf 2393 1 Specific specific JJ cord-022526-j9kg00qf 2393 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 2393 3 procedures procedure NNS cord-022526-j9kg00qf 2393 4 for for IN cord-022526-j9kg00qf 2393 5 nonalimentary nonalimentary JJ cord-022526-j9kg00qf 2393 6 causes cause NNS cord-022526-j9kg00qf 2393 7 of of IN cord-022526-j9kg00qf 2393 8 dysphagia dysphagia NN cord-022526-j9kg00qf 2393 9 are be VBP cord-022526-j9kg00qf 2393 10 covered cover VBN cord-022526-j9kg00qf 2393 11 elsewhere elsewhere RB cord-022526-j9kg00qf 2393 12 in in IN cord-022526-j9kg00qf 2393 13 this this DT cord-022526-j9kg00qf 2393 14 text text NN cord-022526-j9kg00qf 2393 15 ( ( -LRB- cord-022526-j9kg00qf 2393 16 see see VB cord-022526-j9kg00qf 2393 17 Chapter chapter NN cord-022526-j9kg00qf 2393 18 3 3 CD cord-022526-j9kg00qf 2393 19 ) ) -RRB- cord-022526-j9kg00qf 2393 20 . . . cord-022526-j9kg00qf 2394 1 Specific specific JJ cord-022526-j9kg00qf 2394 2 treatments treatment NNS cord-022526-j9kg00qf 2394 3 aimed aim VBN cord-022526-j9kg00qf 2394 4 at at IN cord-022526-j9kg00qf 2394 5 resolving resolve VBG cord-022526-j9kg00qf 2394 6 the the DT cord-022526-j9kg00qf 2394 7 underlying underlie VBG cord-022526-j9kg00qf 2394 8 disorder disorder NN cord-022526-j9kg00qf 2394 9 causing cause VBG cord-022526-j9kg00qf 2394 10 dysphagia dysphagia NN cord-022526-j9kg00qf 2394 11 are be VBP cord-022526-j9kg00qf 2394 12 discussed discuss VBN cord-022526-j9kg00qf 2394 13 in in IN cord-022526-j9kg00qf 2394 14 detail detail NN cord-022526-j9kg00qf 2394 15 elsewhere elsewhere RB cord-022526-j9kg00qf 2394 16 . . . cord-022526-j9kg00qf 2395 1 One one PRP cord-022526-j9kg00qf 2395 2 should should MD cord-022526-j9kg00qf 2395 3 avoid avoid VB cord-022526-j9kg00qf 2395 4 feeding feed VBG cord-022526-j9kg00qf 2395 5 roughage roughage NN cord-022526-j9kg00qf 2395 6 with with IN cord-022526-j9kg00qf 2395 7 long long JJ cord-022526-j9kg00qf 2395 8 fiber fiber NN cord-022526-j9kg00qf 2395 9 length length NN cord-022526-j9kg00qf 2395 10 ( ( -LRB- cord-022526-j9kg00qf 2395 11 hay hay NN cord-022526-j9kg00qf 2395 12 or or CC cord-022526-j9kg00qf 2395 13 grass grass NN cord-022526-j9kg00qf 2395 14 ) ) -RRB- cord-022526-j9kg00qf 2395 15 to to IN cord-022526-j9kg00qf 2395 16 most most JJS cord-022526-j9kg00qf 2395 17 horses horse NNS cord-022526-j9kg00qf 2395 18 with with IN cord-022526-j9kg00qf 2395 19 dysphagia dysphagia NN cord-022526-j9kg00qf 2395 20 . . . cord-022526-j9kg00qf 2396 1 Dietary dietary JJ cord-022526-j9kg00qf 2396 2 modifications modification NNS cord-022526-j9kg00qf 2396 3 that that WDT cord-022526-j9kg00qf 2396 4 promote promote VBP cord-022526-j9kg00qf 2396 5 swallowing swallow VBG cord-022526-j9kg00qf 2396 6 such such JJ cord-022526-j9kg00qf 2396 7 as as IN cord-022526-j9kg00qf 2396 8 feeding feeding NN cord-022526-j9kg00qf 2396 9 slurries slurry NNS cord-022526-j9kg00qf 2396 10 made make VBN cord-022526-j9kg00qf 2396 11 from from IN cord-022526-j9kg00qf 2396 12 complete complete JJ cord-022526-j9kg00qf 2396 13 pelleted pelleted JJ cord-022526-j9kg00qf 2396 14 feeds feed NNS cord-022526-j9kg00qf 2396 15 may may MD cord-022526-j9kg00qf 2396 16 be be VB cord-022526-j9kg00qf 2396 17 sufficient sufficient JJ cord-022526-j9kg00qf 2396 18 to to TO cord-022526-j9kg00qf 2396 19 manage manage VB cord-022526-j9kg00qf 2396 20 some some DT cord-022526-j9kg00qf 2396 21 cases case NNS cord-022526-j9kg00qf 2396 22 of of IN cord-022526-j9kg00qf 2396 23 partial partial JJ cord-022526-j9kg00qf 2396 24 dysphagia dysphagia NN cord-022526-j9kg00qf 2396 25 . . . cord-022526-j9kg00qf 2397 1 One one PRP cord-022526-j9kg00qf 2397 2 must must MD cord-022526-j9kg00qf 2397 3 take take VB cord-022526-j9kg00qf 2397 4 care care NN cord-022526-j9kg00qf 2397 5 to to TO cord-022526-j9kg00qf 2397 6 prevent prevent VB cord-022526-j9kg00qf 2397 7 or or CC cord-022526-j9kg00qf 2397 8 avoid avoid VB cord-022526-j9kg00qf 2397 9 aspiration aspiration NN cord-022526-j9kg00qf 2397 10 pneumonia pneumonia NN cord-022526-j9kg00qf 2397 11 in in IN cord-022526-j9kg00qf 2397 12 horses horse NNS cord-022526-j9kg00qf 2397 13 with with IN cord-022526-j9kg00qf 2397 14 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2397 15 or or CC cord-022526-j9kg00qf 2397 16 esophageal esophageal JJ cord-022526-j9kg00qf 2397 17 dysphagia dysphagia NN cord-022526-j9kg00qf 2397 18 . . . cord-022526-j9kg00qf 2398 1 One one PRP cord-022526-j9kg00qf 2398 2 can can MD cord-022526-j9kg00qf 2398 3 manage manage VB cord-022526-j9kg00qf 2398 4 foals foal NNS cord-022526-j9kg00qf 2398 5 by by IN cord-022526-j9kg00qf 2398 6 feeding feed VBG cord-022526-j9kg00qf 2398 7 mare mare NNP cord-022526-j9kg00qf 2398 8 's 's POS cord-022526-j9kg00qf 2398 9 milk milk NN cord-022526-j9kg00qf 2398 10 or or CC cord-022526-j9kg00qf 2398 11 a a DT cord-022526-j9kg00qf 2398 12 suitable suitable JJ cord-022526-j9kg00qf 2398 13 substitute substitute NN cord-022526-j9kg00qf 2398 14 through through IN cord-022526-j9kg00qf 2398 15 a a DT cord-022526-j9kg00qf 2398 16 nasogastric nasogastric NN cord-022526-j9kg00qf 2398 17 tube tube NN cord-022526-j9kg00qf 2398 18 . . . cord-022526-j9kg00qf 2399 1 One one CD cord-022526-j9kg00qf 2399 2 also also RB cord-022526-j9kg00qf 2399 3 may may MD cord-022526-j9kg00qf 2399 4 administer administer VB cord-022526-j9kg00qf 2399 5 pellet pellet NN cord-022526-j9kg00qf 2399 6 slurries slurry NNS cord-022526-j9kg00qf 2399 7 or or CC cord-022526-j9kg00qf 2399 8 formulated formulate VBN cord-022526-j9kg00qf 2399 9 liquid liquid JJ cord-022526-j9kg00qf 2399 10 diets diet NNS cord-022526-j9kg00qf 2399 11 via via IN cord-022526-j9kg00qf 2399 12 nasogastric nasogastric NN cord-022526-j9kg00qf 2399 13 tubes tube NNS cord-022526-j9kg00qf 2399 14 to to IN cord-022526-j9kg00qf 2399 15 older old JJR cord-022526-j9kg00qf 2399 16 horses horse NNS cord-022526-j9kg00qf 2399 17 . . . cord-022526-j9kg00qf 2400 1 Prolonged prolonged JJ cord-022526-j9kg00qf 2400 2 nutritional nutritional JJ cord-022526-j9kg00qf 2400 3 management management NN cord-022526-j9kg00qf 2400 4 of of IN cord-022526-j9kg00qf 2400 5 dysphagic dysphagic JJ cord-022526-j9kg00qf 2400 6 horses horse NNS cord-022526-j9kg00qf 2400 7 may may MD cord-022526-j9kg00qf 2400 8 require require VB cord-022526-j9kg00qf 2400 9 extraoral extraoral JJ cord-022526-j9kg00qf 2400 10 feeding feeding NN cord-022526-j9kg00qf 2400 11 using use VBG cord-022526-j9kg00qf 2400 12 a a DT cord-022526-j9kg00qf 2400 13 tube tube NN cord-022526-j9kg00qf 2400 14 placed place VBN cord-022526-j9kg00qf 2400 15 through through IN cord-022526-j9kg00qf 2400 16 an an DT cord-022526-j9kg00qf 2400 17 esophagostomy esophagostomy NN cord-022526-j9kg00qf 2400 18 . . . cord-022526-j9kg00qf 2401 1 6 6 CD cord-022526-j9kg00qf 2402 1 Formulated formulate VBN cord-022526-j9kg00qf 2402 2 pelleted pellete VBN cord-022526-j9kg00qf 2402 3 diets diet NNS cord-022526-j9kg00qf 2402 4 are be VBP cord-022526-j9kg00qf 2402 5 often often RB cord-022526-j9kg00qf 2402 6 easy easy JJ cord-022526-j9kg00qf 2402 7 to to TO cord-022526-j9kg00qf 2402 8 administer administer VB cord-022526-j9kg00qf 2402 9 through through IN cord-022526-j9kg00qf 2402 10 a a DT cord-022526-j9kg00qf 2402 11 tube tube NN cord-022526-j9kg00qf 2402 12 as as IN cord-022526-j9kg00qf 2402 13 slurry slurry NN cord-022526-j9kg00qf 2402 14 and and CC cord-022526-j9kg00qf 2402 15 are be VBP cord-022526-j9kg00qf 2402 16 balanced balanced JJ cord-022526-j9kg00qf 2402 17 to to TO cord-022526-j9kg00qf 2402 18 meet meet VB cord-022526-j9kg00qf 2402 19 the the DT cord-022526-j9kg00qf 2402 20 nutritional nutritional JJ cord-022526-j9kg00qf 2402 21 requirements requirement NNS cord-022526-j9kg00qf 2402 22 for for IN cord-022526-j9kg00qf 2402 23 healthy healthy JJ cord-022526-j9kg00qf 2402 24 horses horse NNS cord-022526-j9kg00qf 2402 25 . . . cord-022526-j9kg00qf 2403 1 One one PRP cord-022526-j9kg00qf 2403 2 must must MD cord-022526-j9kg00qf 2403 3 feed feed VB cord-022526-j9kg00qf 2403 4 sufficient sufficient JJ cord-022526-j9kg00qf 2403 5 quantities quantity NNS cord-022526-j9kg00qf 2403 6 to to TO cord-022526-j9kg00qf 2403 7 deliver deliver VB cord-022526-j9kg00qf 2403 8 adequate adequate JJ cord-022526-j9kg00qf 2403 9 calories calorie NNS cord-022526-j9kg00qf 2403 10 ( ( -LRB- cord-022526-j9kg00qf 2403 11 16 16 CD cord-022526-j9kg00qf 2403 12 to to TO cord-022526-j9kg00qf 2403 13 17 17 CD cord-022526-j9kg00qf 2403 14 Mcal Mcal NNP cord-022526-j9kg00qf 2403 15 / / SYM cord-022526-j9kg00qf 2403 16 day day NN cord-022526-j9kg00qf 2403 17 for for IN cord-022526-j9kg00qf 2403 18 a a DT cord-022526-j9kg00qf 2403 19 500-kg 500-kg CD cord-022526-j9kg00qf 2403 20 horse horse NN cord-022526-j9kg00qf 2403 21 ) ) -RRB- cord-022526-j9kg00qf 2403 22 . . . cord-022526-j9kg00qf 2404 1 Adjustments adjustment NNS cord-022526-j9kg00qf 2404 2 may may MD cord-022526-j9kg00qf 2404 3 be be VB cord-022526-j9kg00qf 2404 4 necessary necessary JJ cord-022526-j9kg00qf 2404 5 for for IN cord-022526-j9kg00qf 2404 6 horses horse NNS cord-022526-j9kg00qf 2404 7 that that WDT cord-022526-j9kg00qf 2404 8 are be VBP cord-022526-j9kg00qf 2404 9 cachectic cachectic VBN cord-022526-j9kg00qf 2404 10 or or CC cord-022526-j9kg00qf 2404 11 have have VBP cord-022526-j9kg00qf 2404 12 extra extra JJ cord-022526-j9kg00qf 2404 13 metabolic metabolic JJ cord-022526-j9kg00qf 2404 14 demand demand NN cord-022526-j9kg00qf 2404 15 ( ( -LRB- cord-022526-j9kg00qf 2404 16 such such JJ cord-022526-j9kg00qf 2404 17 as as IN cord-022526-j9kg00qf 2404 18 pregnancy pregnancy NN cord-022526-j9kg00qf 2404 19 ) ) -RRB- cord-022526-j9kg00qf 2404 20 . . . cord-022526-j9kg00qf 2405 1 Adding add VBG cord-022526-j9kg00qf 2405 2 corn corn NN cord-022526-j9kg00qf 2405 3 oil oil NN cord-022526-j9kg00qf 2405 4 to to IN cord-022526-j9kg00qf 2405 5 the the DT cord-022526-j9kg00qf 2405 6 ration ration NN cord-022526-j9kg00qf 2405 7 ( ( -LRB- cord-022526-j9kg00qf 2405 8 1 1 CD cord-022526-j9kg00qf 2405 9 cup cup NN cord-022526-j9kg00qf 2405 10 every every DT cord-022526-j9kg00qf 2405 11 12 12 CD cord-022526-j9kg00qf 2405 12 or or CC cord-022526-j9kg00qf 2405 13 24 24 CD cord-022526-j9kg00qf 2405 14 hours hour NNS cord-022526-j9kg00qf 2405 15 ) ) -RRB- cord-022526-j9kg00qf 2405 16 is be VBZ cord-022526-j9kg00qf 2405 17 a a DT cord-022526-j9kg00qf 2405 18 common common JJ cord-022526-j9kg00qf 2405 19 method method NN cord-022526-j9kg00qf 2405 20 of of IN cord-022526-j9kg00qf 2405 21 increasing increase VBG cord-022526-j9kg00qf 2405 22 fed fed NNP cord-022526-j9kg00qf 2405 23 calories calorie NNS cord-022526-j9kg00qf 2405 24 . . . cord-022526-j9kg00qf 2406 1 Liquid liquid NN cord-022526-j9kg00qf 2406 2 diets diet NNS cord-022526-j9kg00qf 2406 3 also also RB cord-022526-j9kg00qf 2406 4 have have VBP cord-022526-j9kg00qf 2406 5 been be VBN cord-022526-j9kg00qf 2406 6 used use VBN cord-022526-j9kg00qf 2406 7 for for IN cord-022526-j9kg00qf 2406 8 enteral enteral JJ cord-022526-j9kg00qf 2406 9 feeding feed VBG cord-022526-j9kg00qf 2406 10 7 7 CD cord-022526-j9kg00qf 2406 11 but but CC cord-022526-j9kg00qf 2406 12 may may MD cord-022526-j9kg00qf 2406 13 not not RB cord-022526-j9kg00qf 2406 14 be be VB cord-022526-j9kg00qf 2406 15 tolerated tolerate VBN cord-022526-j9kg00qf 2406 16 as as RB cord-022526-j9kg00qf 2406 17 well well RB cord-022526-j9kg00qf 2406 18 as as IN cord-022526-j9kg00qf 2406 19 pelleted pellete VBN cord-022526-j9kg00qf 2406 20 diets diet NNS cord-022526-j9kg00qf 2406 21 . . . cord-022526-j9kg00qf 2407 1 Regardless regardless RB cord-022526-j9kg00qf 2407 2 of of IN cord-022526-j9kg00qf 2407 3 the the DT cord-022526-j9kg00qf 2407 4 method method NN cord-022526-j9kg00qf 2407 5 of of IN cord-022526-j9kg00qf 2407 6 nutritional nutritional JJ cord-022526-j9kg00qf 2407 7 management management NN cord-022526-j9kg00qf 2407 8 , , , cord-022526-j9kg00qf 2407 9 one one PRP cord-022526-j9kg00qf 2407 10 must must MD cord-022526-j9kg00qf 2407 11 monitor monitor VB cord-022526-j9kg00qf 2407 12 and and CC cord-022526-j9kg00qf 2407 13 replace replace VB cord-022526-j9kg00qf 2407 14 salivary salivary JJ cord-022526-j9kg00qf 2407 15 losses loss NNS cord-022526-j9kg00qf 2407 16 of of IN cord-022526-j9kg00qf 2407 17 electrolytes electrolyte NNS cord-022526-j9kg00qf 2407 18 . . . cord-022526-j9kg00qf 2408 1 Saliva saliva NN cord-022526-j9kg00qf 2408 2 contains contain VBZ cord-022526-j9kg00qf 2408 3 high high JJ cord-022526-j9kg00qf 2408 4 concentrations concentration NNS cord-022526-j9kg00qf 2408 5 of of IN cord-022526-j9kg00qf 2408 6 Na Na NNP cord-022526-j9kg00qf 2408 7 , , , cord-022526-j9kg00qf 2408 8 K K NNP cord-022526-j9kg00qf 2408 9 , , , cord-022526-j9kg00qf 2408 10 and and CC cord-022526-j9kg00qf 2408 11 Cl Cl NNP cord-022526-j9kg00qf 2408 12 . . . cord-022526-j9kg00qf 2409 1 A a DT cord-022526-j9kg00qf 2409 2 group group NN cord-022526-j9kg00qf 2409 3 of of IN cord-022526-j9kg00qf 2409 4 ponies pony NNS cord-022526-j9kg00qf 2409 5 with with IN cord-022526-j9kg00qf 2409 6 experimental experimental JJ cord-022526-j9kg00qf 2409 7 esophagostomies esophagostomie NNS cord-022526-j9kg00qf 2409 8 8 8 CD cord-022526-j9kg00qf 2409 9 and and CC cord-022526-j9kg00qf 2409 10 a a DT cord-022526-j9kg00qf 2409 11 horse horse NN cord-022526-j9kg00qf 2409 12 with with IN cord-022526-j9kg00qf 2409 13 esophageal esophageal JJ cord-022526-j9kg00qf 2409 14 squamous squamous JJ cord-022526-j9kg00qf 2409 15 cell cell NN cord-022526-j9kg00qf 2409 16 carcinoma carcinoma NN cord-022526-j9kg00qf 2409 17 9 9 CD cord-022526-j9kg00qf 2409 18 were be VBD cord-022526-j9kg00qf 2409 19 fed feed VBN cord-022526-j9kg00qf 2409 20 a a DT cord-022526-j9kg00qf 2409 21 complete complete JJ cord-022526-j9kg00qf 2409 22 pelleted pellete VBN cord-022526-j9kg00qf 2409 23 diet diet NN cord-022526-j9kg00qf 2409 24 through through IN cord-022526-j9kg00qf 2409 25 esophagostomy esophagostomy JJ cord-022526-j9kg00qf 2409 26 tubes tube NNS cord-022526-j9kg00qf 2409 27 but but CC cord-022526-j9kg00qf 2409 28 developed develop VBD cord-022526-j9kg00qf 2409 29 metabolic metabolic JJ cord-022526-j9kg00qf 2409 30 acidosis acidosis NN cord-022526-j9kg00qf 2409 31 , , , cord-022526-j9kg00qf 2409 32 hyponatremia hyponatremia NN cord-022526-j9kg00qf 2409 33 , , , cord-022526-j9kg00qf 2409 34 and and CC cord-022526-j9kg00qf 2409 35 hypochloremia hypochloremia NN cord-022526-j9kg00qf 2409 36 apparently apparently RB cord-022526-j9kg00qf 2409 37 because because IN cord-022526-j9kg00qf 2409 38 of of IN cord-022526-j9kg00qf 2409 39 salivary salivary JJ cord-022526-j9kg00qf 2409 40 losses loss NNS cord-022526-j9kg00qf 2409 41 . . . cord-022526-j9kg00qf 2410 1 Surprisingly surprisingly RB cord-022526-j9kg00qf 2410 2 , , , cord-022526-j9kg00qf 2410 3 salivary salivary JJ cord-022526-j9kg00qf 2410 4 losses loss NNS cord-022526-j9kg00qf 2410 5 of of IN cord-022526-j9kg00qf 2410 6 potassium potassium NN cord-022526-j9kg00qf 2410 7 did do VBD cord-022526-j9kg00qf 2410 8 not not RB cord-022526-j9kg00qf 2410 9 result result VB cord-022526-j9kg00qf 2410 10 in in IN cord-022526-j9kg00qf 2410 11 hypokalemia hypokalemia NN cord-022526-j9kg00qf 2410 12 in in IN cord-022526-j9kg00qf 2410 13 these these DT cord-022526-j9kg00qf 2410 14 cases case NNS cord-022526-j9kg00qf 2410 15 , , , cord-022526-j9kg00qf 2410 16 presumably presumably RB cord-022526-j9kg00qf 2410 17 because because IN cord-022526-j9kg00qf 2410 18 of of IN cord-022526-j9kg00qf 2410 19 replacement replacement NN cord-022526-j9kg00qf 2410 20 in in IN cord-022526-j9kg00qf 2410 21 the the DT cord-022526-j9kg00qf 2410 22 diet diet NN cord-022526-j9kg00qf 2410 23 . . . cord-022526-j9kg00qf 2411 1 However however RB cord-022526-j9kg00qf 2411 2 , , , cord-022526-j9kg00qf 2411 3 if if IN cord-022526-j9kg00qf 2411 4 the the DT cord-022526-j9kg00qf 2411 5 diet diet NN cord-022526-j9kg00qf 2411 6 is be VBZ cord-022526-j9kg00qf 2411 7 deficient deficient JJ cord-022526-j9kg00qf 2411 8 in in IN cord-022526-j9kg00qf 2411 9 potassium potassium NN cord-022526-j9kg00qf 2411 10 , , , cord-022526-j9kg00qf 2411 11 hypokalemia hypokalemia NN cord-022526-j9kg00qf 2411 12 may may MD cord-022526-j9kg00qf 2411 13 result result VB cord-022526-j9kg00qf 2411 14 . . . cord-022526-j9kg00qf 2412 1 One one CD cord-022526-j9kg00qf 2412 2 often often RB cord-022526-j9kg00qf 2412 3 can can MD cord-022526-j9kg00qf 2412 4 accomplish accomplish VB cord-022526-j9kg00qf 2412 5 electrolyte electrolyte JJ cord-022526-j9kg00qf 2412 6 replacement replacement NN cord-022526-j9kg00qf 2412 7 by by IN cord-022526-j9kg00qf 2412 8 adding add VBG cord-022526-j9kg00qf 2412 9 NaCl NaCl NNP cord-022526-j9kg00qf 2412 10 and and CC cord-022526-j9kg00qf 2412 11 KCl KCl NNS cord-022526-j9kg00qf 2412 12 to to IN cord-022526-j9kg00qf 2412 13 the the DT cord-022526-j9kg00qf 2412 14 diet diet NN cord-022526-j9kg00qf 2412 15 . . . cord-022526-j9kg00qf 2413 1 One one PRP cord-022526-j9kg00qf 2413 2 can can MD cord-022526-j9kg00qf 2413 3 maintain maintain VB cord-022526-j9kg00qf 2413 4 horses horse NNS cord-022526-j9kg00qf 2413 5 for for IN cord-022526-j9kg00qf 2413 6 months month NNS cord-022526-j9kg00qf 2413 7 with with IN cord-022526-j9kg00qf 2413 8 frequent frequent JJ cord-022526-j9kg00qf 2413 9 feedings feeding NNS cord-022526-j9kg00qf 2413 10 through through IN cord-022526-j9kg00qf 2413 11 an an DT cord-022526-j9kg00qf 2413 12 esophagostomy esophagostomy NN cord-022526-j9kg00qf 2413 13 tube tube NN cord-022526-j9kg00qf 2413 14 . . . cord-022526-j9kg00qf 2414 1 9 9 CD cord-022526-j9kg00qf 2415 1 Parenteral parenteral JJ cord-022526-j9kg00qf 2415 2 nutrition nutrition NN cord-022526-j9kg00qf 2415 3 ( ( -LRB- cord-022526-j9kg00qf 2415 4 total total JJ cord-022526-j9kg00qf 2415 5 or or CC cord-022526-j9kg00qf 2415 6 partial partial JJ cord-022526-j9kg00qf 2415 7 ) ) -RRB- cord-022526-j9kg00qf 2415 8 may may MD cord-022526-j9kg00qf 2415 9 be be VB cord-022526-j9kg00qf 2415 10 useful useful JJ cord-022526-j9kg00qf 2415 11 in in IN cord-022526-j9kg00qf 2415 12 the the DT cord-022526-j9kg00qf 2415 13 short short JJ cord-022526-j9kg00qf 2415 14 term term NN cord-022526-j9kg00qf 2415 15 but but CC cord-022526-j9kg00qf 2415 16 is be VBZ cord-022526-j9kg00qf 2415 17 not not RB cord-022526-j9kg00qf 2415 18 often often RB cord-022526-j9kg00qf 2415 19 feasible feasible JJ cord-022526-j9kg00qf 2415 20 for for IN cord-022526-j9kg00qf 2415 21 long long JJ cord-022526-j9kg00qf 2415 22 - - HYPH cord-022526-j9kg00qf 2415 23 term term NN cord-022526-j9kg00qf 2415 24 management management NN cord-022526-j9kg00qf 2415 25 . . . cord-022526-j9kg00qf 2416 1 Tooth tooth NN cord-022526-j9kg00qf 2416 2 eruption eruption NN cord-022526-j9kg00qf 2416 3 is be VBZ cord-022526-j9kg00qf 2416 4 a a DT cord-022526-j9kg00qf 2416 5 complex complex JJ cord-022526-j9kg00qf 2416 6 phenomenon phenomenon NN cord-022526-j9kg00qf 2416 7 involving involve VBG cord-022526-j9kg00qf 2416 8 the the DT cord-022526-j9kg00qf 2416 9 interplay interplay NN cord-022526-j9kg00qf 2416 10 of of IN cord-022526-j9kg00qf 2416 11 dental dental JJ cord-022526-j9kg00qf 2416 12 morphogenesis morphogenesis NN cord-022526-j9kg00qf 2416 13 and and CC cord-022526-j9kg00qf 2416 14 those those DT cord-022526-j9kg00qf 2416 15 vascular vascular JJ cord-022526-j9kg00qf 2416 16 forces force NNS cord-022526-j9kg00qf 2416 17 responsible responsible JJ cord-022526-j9kg00qf 2416 18 for for IN cord-022526-j9kg00qf 2416 19 creating create VBG cord-022526-j9kg00qf 2416 20 the the DT cord-022526-j9kg00qf 2416 21 eruption eruption NN cord-022526-j9kg00qf 2416 22 pathway pathway NN cord-022526-j9kg00qf 2416 23 . . . cord-022526-j9kg00qf 2417 1 These these DT cord-022526-j9kg00qf 2417 2 changes change NNS cord-022526-j9kg00qf 2417 3 are be VBP cord-022526-j9kg00qf 2417 4 responsible responsible JJ cord-022526-j9kg00qf 2417 5 for for IN cord-022526-j9kg00qf 2417 6 osteitis osteitis NN cord-022526-j9kg00qf 2417 7 and and CC cord-022526-j9kg00qf 2417 8 bone bone NN cord-022526-j9kg00qf 2417 9 remodeling remodeling NN cord-022526-j9kg00qf 2417 10 within within IN cord-022526-j9kg00qf 2417 11 the the DT cord-022526-j9kg00qf 2417 12 maxilla maxilla NN cord-022526-j9kg00qf 2417 13 and and CC cord-022526-j9kg00qf 2417 14 mandible mandible NN cord-022526-j9kg00qf 2417 15 . . . cord-022526-j9kg00qf 2418 1 Young young JJ cord-022526-j9kg00qf 2418 2 horses horse NNS cord-022526-j9kg00qf 2418 3 frequently frequently RB cord-022526-j9kg00qf 2418 4 show show VBP cord-022526-j9kg00qf 2418 5 symmetric symmetric JJ cord-022526-j9kg00qf 2418 6 bony bony JJ cord-022526-j9kg00qf 2418 7 swelling swelling NN cord-022526-j9kg00qf 2418 8 resulting result VBG cord-022526-j9kg00qf 2418 9 from from IN cord-022526-j9kg00qf 2418 10 these these DT cord-022526-j9kg00qf 2418 11 eruption eruption NN cord-022526-j9kg00qf 2418 12 cysts cyst NNS cord-022526-j9kg00qf 2418 13 . . . cord-022526-j9kg00qf 2419 1 In in IN cord-022526-j9kg00qf 2419 2 some some DT cord-022526-j9kg00qf 2419 3 cases case NNS cord-022526-j9kg00qf 2419 4 , , , cord-022526-j9kg00qf 2419 5 additional additional JJ cord-022526-j9kg00qf 2419 6 clinical clinical JJ cord-022526-j9kg00qf 2419 7 signs sign NNS cord-022526-j9kg00qf 2419 8 of of IN cord-022526-j9kg00qf 2419 9 nasal nasal JJ cord-022526-j9kg00qf 2419 10 obstruction obstruction NN cord-022526-j9kg00qf 2419 11 with with IN cord-022526-j9kg00qf 2419 12 respiratory respiratory JJ cord-022526-j9kg00qf 2419 13 stridor stridor NNS cord-022526-j9kg00qf 2419 14 or or CC cord-022526-j9kg00qf 2419 15 nasal nasal NN cord-022526-j9kg00qf 2419 16 discharges discharge NNS cord-022526-j9kg00qf 2419 17 may may MD cord-022526-j9kg00qf 2419 18 be be VB cord-022526-j9kg00qf 2419 19 apparent apparent JJ cord-022526-j9kg00qf 2419 20 . . . cord-022526-j9kg00qf 2420 1 Pathologic pathologic JJ cord-022526-j9kg00qf 2420 2 problems problem NNS cord-022526-j9kg00qf 2420 3 associated associate VBN cord-022526-j9kg00qf 2420 4 with with IN cord-022526-j9kg00qf 2420 5 maleruption maleruption NN cord-022526-j9kg00qf 2420 6 include include VBP cord-022526-j9kg00qf 2420 7 a a DT cord-022526-j9kg00qf 2420 8 variety variety NN cord-022526-j9kg00qf 2420 9 of of IN cord-022526-j9kg00qf 2420 10 dental dental JJ cord-022526-j9kg00qf 2420 11 diseases disease NNS cord-022526-j9kg00qf 2420 12 . . . cord-022526-j9kg00qf 2421 1 Oral oral JJ cord-022526-j9kg00qf 2421 2 trauma trauma NN cord-022526-j9kg00qf 2421 3 can can MD cord-022526-j9kg00qf 2421 4 displace displace VB cord-022526-j9kg00qf 2421 5 or or CC cord-022526-j9kg00qf 2421 6 damage damage NN cord-022526-j9kg00qf 2421 7 erupting erupt VBG cord-022526-j9kg00qf 2421 8 teeth tooth NNS cord-022526-j9kg00qf 2421 9 or or CC cord-022526-j9kg00qf 2421 10 the the DT cord-022526-j9kg00qf 2421 11 permanent permanent JJ cord-022526-j9kg00qf 2421 12 tooth tooth NN cord-022526-j9kg00qf 2421 13 buds bud NNS cord-022526-j9kg00qf 2421 14 . . . cord-022526-j9kg00qf 2422 1 As as IN cord-022526-j9kg00qf 2422 2 a a DT cord-022526-j9kg00qf 2422 3 result result NN cord-022526-j9kg00qf 2422 4 , , , cord-022526-j9kg00qf 2422 5 teeth tooth NNS cord-022526-j9kg00qf 2422 6 may may MD cord-022526-j9kg00qf 2422 7 be be VB cord-022526-j9kg00qf 2422 8 displaced displace VBN cord-022526-j9kg00qf 2422 9 and and CC cord-022526-j9kg00qf 2422 10 erupt erupt VB cord-022526-j9kg00qf 2422 11 in in IN cord-022526-j9kg00qf 2422 12 abnormal abnormal JJ cord-022526-j9kg00qf 2422 13 positions position NNS cord-022526-j9kg00qf 2422 14 or or CC cord-022526-j9kg00qf 2422 15 may may MD cord-022526-j9kg00qf 2422 16 have have VB cord-022526-j9kg00qf 2422 17 abnormal abnormal JJ cord-022526-j9kg00qf 2422 18 shapes shape NNS cord-022526-j9kg00qf 2422 19 . . . cord-022526-j9kg00qf 2423 1 Supernumerary supernumerary JJ cord-022526-j9kg00qf 2423 2 teeth tooth NNS cord-022526-j9kg00qf 2423 3 , , , cord-022526-j9kg00qf 2423 4 incisors incisor NNS cord-022526-j9kg00qf 2423 5 and and CC cord-022526-j9kg00qf 2423 6 molars molar NNS cord-022526-j9kg00qf 2423 7 , , , cord-022526-j9kg00qf 2423 8 can can MD cord-022526-j9kg00qf 2423 9 develop develop VB cord-022526-j9kg00qf 2423 10 , , , cord-022526-j9kg00qf 2423 11 as as RB cord-022526-j9kg00qf 2423 12 well well RB cord-022526-j9kg00qf 2423 13 as as IN cord-022526-j9kg00qf 2423 14 palatal palatal JJ cord-022526-j9kg00qf 2423 15 displacement displacement NN cord-022526-j9kg00qf 2423 16 of of IN cord-022526-j9kg00qf 2423 17 impacted impact VBN cord-022526-j9kg00qf 2423 18 teeth tooth NNS cord-022526-j9kg00qf 2423 19 ( ( -LRB- cord-022526-j9kg00qf 2423 20 maxillary maxillary JJ cord-022526-j9kg00qf 2423 21 P3 P3 NNP cord-022526-j9kg00qf 2423 22 - - HYPH cord-022526-j9kg00qf 2423 23 3 3 CD cord-022526-j9kg00qf 2423 24 , , , cord-022526-j9kg00qf 2423 25 or or CC cord-022526-j9kg00qf 2423 26 third third JJ cord-022526-j9kg00qf 2423 27 cheek cheek NN cord-022526-j9kg00qf 2423 28 tooth tooth NN cord-022526-j9kg00qf 2423 29 ) ) -RRB- cord-022526-j9kg00qf 2423 30 . . . cord-022526-j9kg00qf 2424 1 In in IN cord-022526-j9kg00qf 2424 2 almost almost RB cord-022526-j9kg00qf 2424 3 all all DT cord-022526-j9kg00qf 2424 4 of of IN cord-022526-j9kg00qf 2424 5 these these DT cord-022526-j9kg00qf 2424 6 conditions condition NNS cord-022526-j9kg00qf 2424 7 some some DT cord-022526-j9kg00qf 2424 8 form form NN cord-022526-j9kg00qf 2424 9 of of IN cord-022526-j9kg00qf 2424 10 surgical surgical JJ cord-022526-j9kg00qf 2424 11 treatment treatment NN cord-022526-j9kg00qf 2424 12 is be VBZ cord-022526-j9kg00qf 2424 13 necessary necessary JJ cord-022526-j9kg00qf 2424 14 . . . cord-022526-j9kg00qf 2425 1 Significant significant JJ cord-022526-j9kg00qf 2425 2 evidence evidence NN cord-022526-j9kg00qf 2425 3 from from IN cord-022526-j9kg00qf 2425 4 the the DT cord-022526-j9kg00qf 2425 5 location location NN cord-022526-j9kg00qf 2425 6 of of IN cord-022526-j9kg00qf 2425 7 apical apical JJ cord-022526-j9kg00qf 2425 8 osteitis osteitis NN cord-022526-j9kg00qf 2425 9 in in IN cord-022526-j9kg00qf 2425 10 diseased diseased JJ cord-022526-j9kg00qf 2425 11 teeth tooth NNS cord-022526-j9kg00qf 2425 12 ( ( -LRB- cord-022526-j9kg00qf 2425 13 Table table NN cord-022526-j9kg00qf 2425 14 13 13 CD cord-022526-j9kg00qf 2425 15 .8 .8 CD cord-022526-j9kg00qf 2425 16 - - SYM cord-022526-j9kg00qf 2425 17 3 3 CD cord-022526-j9kg00qf 2425 18 ) ) -RRB- cord-022526-j9kg00qf 2425 19 confirms confirm VBZ cord-022526-j9kg00qf 2425 20 that that IN cord-022526-j9kg00qf 2425 21 dental dental JJ cord-022526-j9kg00qf 2425 22 impaction impaction NN cord-022526-j9kg00qf 2425 23 is be VBZ cord-022526-j9kg00qf 2425 24 a a DT cord-022526-j9kg00qf 2425 25 major major JJ cord-022526-j9kg00qf 2425 26 cause cause NN cord-022526-j9kg00qf 2425 27 of of IN cord-022526-j9kg00qf 2425 28 dental dental JJ cord-022526-j9kg00qf 2425 29 disease disease NN cord-022526-j9kg00qf 2425 30 in in IN cord-022526-j9kg00qf 2425 31 the the DT cord-022526-j9kg00qf 2425 32 horse horse NN cord-022526-j9kg00qf 2425 33 . . . cord-022526-j9kg00qf 2426 1 In in IN cord-022526-j9kg00qf 2426 2 a a DT cord-022526-j9kg00qf 2426 3 series series NN cord-022526-j9kg00qf 2426 4 of of IN cord-022526-j9kg00qf 2426 5 142 142 CD cord-022526-j9kg00qf 2426 6 extracted extract VBN cord-022526-j9kg00qf 2426 7 teeth tooth NNS cord-022526-j9kg00qf 2426 8 , , , cord-022526-j9kg00qf 2426 9 63 63 CD cord-022526-j9kg00qf 2426 10 were be VBD cord-022526-j9kg00qf 2426 11 P3 P3 NNP cord-022526-j9kg00qf 2426 12 - - HYPH cord-022526-j9kg00qf 2426 13 3 3 CD cord-022526-j9kg00qf 2426 14 or or CC cord-022526-j9kg00qf 2426 15 P4 P4 NNP cord-022526-j9kg00qf 2426 16 - - HYPH cord-022526-j9kg00qf 2426 17 4 4 CD cord-022526-j9kg00qf 2426 18 ( ( -LRB- cord-022526-j9kg00qf 2426 19 cheek cheek NN cord-022526-j9kg00qf 2426 20 tooth tooth NN cord-022526-j9kg00qf 2426 21 2 2 CD cord-022526-j9kg00qf 2426 22 or or CC cord-022526-j9kg00qf 2426 23 3 3 CD cord-022526-j9kg00qf 2426 24 , , , cord-022526-j9kg00qf 2426 25 respectively respectively RB cord-022526-j9kg00qf 2426 26 ) ) -RRB- cord-022526-j9kg00qf 2426 27 . . . cord-022526-j9kg00qf 2427 1 10 10 CD cord-022526-j9kg00qf 2427 2 Early early JJ cord-022526-j9kg00qf 2427 3 observations observation NNS cord-022526-j9kg00qf 2427 4 had have VBD cord-022526-j9kg00qf 2427 5 indicated indicate VBN cord-022526-j9kg00qf 2427 6 that that IN cord-022526-j9kg00qf 2427 7 the the DT cord-022526-j9kg00qf 2427 8 first first JJ cord-022526-j9kg00qf 2427 9 molar molar NN cord-022526-j9kg00qf 2427 10 ( ( -LRB- cord-022526-j9kg00qf 2427 11 M1 M1 NNP cord-022526-j9kg00qf 2427 12 , , , cord-022526-j9kg00qf 2427 13 or or CC cord-022526-j9kg00qf 2427 14 cheek cheek NN cord-022526-j9kg00qf 2427 15 tooth tooth NN cord-022526-j9kg00qf 2427 16 4 4 CD cord-022526-j9kg00qf 2427 17 ) ) -RRB- cord-022526-j9kg00qf 2427 18 was be VBD cord-022526-j9kg00qf 2427 19 the the DT cord-022526-j9kg00qf 2427 20 most most RBS cord-022526-j9kg00qf 2427 21 commonly commonly RB cord-022526-j9kg00qf 2427 22 diseased diseased JJ cord-022526-j9kg00qf 2427 23 tooth tooth NN cord-022526-j9kg00qf 2427 24 , , , cord-022526-j9kg00qf 2427 25 and and CC cord-022526-j9kg00qf 2427 26 an an DT cord-022526-j9kg00qf 2427 27 " " `` cord-022526-j9kg00qf 2427 28 open open JJ cord-022526-j9kg00qf 2427 29 infundibulum infundibulum NN cord-022526-j9kg00qf 2427 30 " " '' cord-022526-j9kg00qf 2427 31 in in IN cord-022526-j9kg00qf 2427 32 this this DT cord-022526-j9kg00qf 2427 33 tooth tooth NN cord-022526-j9kg00qf 2427 34 has have VBZ cord-022526-j9kg00qf 2427 35 been be VBN cord-022526-j9kg00qf 2427 36 suggested suggest VBN cord-022526-j9kg00qf 2427 37 as as IN cord-022526-j9kg00qf 2427 38 the the DT cord-022526-j9kg00qf 2427 39 cause cause NN cord-022526-j9kg00qf 2427 40 . . . cord-022526-j9kg00qf 2428 1 11 11 CD cord-022526-j9kg00qf 2428 2 Studies Studies NNPS cord-022526-j9kg00qf 2428 3 on on IN cord-022526-j9kg00qf 2428 4 cementogenesis cementogenesis NN cord-022526-j9kg00qf 2428 5 of of IN cord-022526-j9kg00qf 2428 6 the the DT cord-022526-j9kg00qf 2428 7 maxillary maxillary JJ cord-022526-j9kg00qf 2428 8 cheek cheek NN cord-022526-j9kg00qf 2428 9 teeth tooth NNS cord-022526-j9kg00qf 2428 10 have have VBP cord-022526-j9kg00qf 2428 11 shown show VBN cord-022526-j9kg00qf 2428 12 , , , cord-022526-j9kg00qf 2428 13 however however RB cord-022526-j9kg00qf 2428 14 , , , cord-022526-j9kg00qf 2428 15 that that IN cord-022526-j9kg00qf 2428 16 in in IN cord-022526-j9kg00qf 2428 17 fact fact NN cord-022526-j9kg00qf 2428 18 most most JJS cord-022526-j9kg00qf 2428 19 maxillary maxillary JJ cord-022526-j9kg00qf 2428 20 cheek cheek NN cord-022526-j9kg00qf 2428 21 teeth tooth NNS cord-022526-j9kg00qf 2428 22 have have VBP cord-022526-j9kg00qf 2428 23 a a DT cord-022526-j9kg00qf 2428 24 greater great JJR cord-022526-j9kg00qf 2428 25 or or CC cord-022526-j9kg00qf 2428 26 lesser less JJR cord-022526-j9kg00qf 2428 27 degree degree NN cord-022526-j9kg00qf 2428 28 of of IN cord-022526-j9kg00qf 2428 29 hypoplasia hypoplasia NN cord-022526-j9kg00qf 2428 30 of of IN cord-022526-j9kg00qf 2428 31 cementum cementum NN cord-022526-j9kg00qf 2428 32 within within IN cord-022526-j9kg00qf 2428 33 the the DT cord-022526-j9kg00qf 2428 34 enamel enamel JJ cord-022526-j9kg00qf 2428 35 lakes lake NNS cord-022526-j9kg00qf 2428 36 and and CC cord-022526-j9kg00qf 2428 37 that that IN cord-022526-j9kg00qf 2428 38 this this DT cord-022526-j9kg00qf 2428 39 " " `` cord-022526-j9kg00qf 2428 40 lesion lesion NN cord-022526-j9kg00qf 2428 41 " " '' cord-022526-j9kg00qf 2428 42 rarely rarely RB cord-022526-j9kg00qf 2428 43 expands expand VBZ cord-022526-j9kg00qf 2428 44 into into IN cord-022526-j9kg00qf 2428 45 the the DT cord-022526-j9kg00qf 2428 46 pulp pulp NN cord-022526-j9kg00qf 2428 47 . . . cord-022526-j9kg00qf 2429 1 The the DT cord-022526-j9kg00qf 2429 2 central central JJ cord-022526-j9kg00qf 2429 3 infundibular infundibular JJ cord-022526-j9kg00qf 2429 4 hole hole NN cord-022526-j9kg00qf 2429 5 is be VBZ cord-022526-j9kg00qf 2429 6 the the DT cord-022526-j9kg00qf 2429 7 site site NN cord-022526-j9kg00qf 2429 8 of of IN cord-022526-j9kg00qf 2429 9 its -PRON- PRP$ cord-022526-j9kg00qf 2429 10 vascular vascular JJ cord-022526-j9kg00qf 2429 11 supply supply NN cord-022526-j9kg00qf 2429 12 to to IN cord-022526-j9kg00qf 2429 13 the the DT cord-022526-j9kg00qf 2429 14 unerupted unerupted NNP cord-022526-j9kg00qf 2429 15 cement cement NNP cord-022526-j9kg00qf 2429 16 lake lake NNP cord-022526-j9kg00qf 2429 17 . . . cord-022526-j9kg00qf 2430 1 On on IN cord-022526-j9kg00qf 2430 2 those those DT cord-022526-j9kg00qf 2430 3 occasions occasion NNS cord-022526-j9kg00qf 2430 4 in in IN cord-022526-j9kg00qf 2430 5 which which WDT cord-022526-j9kg00qf 2430 6 _SP cord-022526-j9kg00qf 2430 7 cases case NNS cord-022526-j9kg00qf 2430 8 one one PRP cord-022526-j9kg00qf 2430 9 can can MD cord-022526-j9kg00qf 2430 10 use use VB cord-022526-j9kg00qf 2430 11 apicoectomy apicoectomy NN cord-022526-j9kg00qf 2430 12 and and CC cord-022526-j9kg00qf 2430 13 retrograde retrograde JJ cord-022526-j9kg00qf 2430 14 endodontic endodontic JJ cord-022526-j9kg00qf 2430 15 techniques technique NNS cord-022526-j9kg00qf 2430 16 to to TO cord-022526-j9kg00qf 2430 17 save save VB cord-022526-j9kg00qf 2430 18 the the DT cord-022526-j9kg00qf 2430 19 diseased diseased JJ cord-022526-j9kg00qf 2430 20 tooth tooth NN cord-022526-j9kg00qf 2430 21 . . . cord-022526-j9kg00qf 2431 1 One one PRP cord-022526-j9kg00qf 2431 2 must must MD cord-022526-j9kg00qf 2431 3 take take VB cord-022526-j9kg00qf 2431 4 care care NN cord-022526-j9kg00qf 2431 5 , , , cord-022526-j9kg00qf 2431 6 however however RB cord-022526-j9kg00qf 2431 7 , , , cord-022526-j9kg00qf 2431 8 in in IN cord-022526-j9kg00qf 2431 9 selection selection NN cord-022526-j9kg00qf 2431 10 of of IN cord-022526-j9kg00qf 2431 11 patients patient NNS cord-022526-j9kg00qf 2431 12 . . . cord-022526-j9kg00qf 2432 1 In in IN cord-022526-j9kg00qf 2432 2 most most JJS cord-022526-j9kg00qf 2432 3 cases case NNS cord-022526-j9kg00qf 2432 4 of of IN cord-022526-j9kg00qf 2432 5 apical apical JJ cord-022526-j9kg00qf 2432 6 osteitis osteitis NN cord-022526-j9kg00qf 2432 7 in in IN cord-022526-j9kg00qf 2432 8 the the DT cord-022526-j9kg00qf 2432 9 horse horse NN cord-022526-j9kg00qf 2432 10 that that WDT cord-022526-j9kg00qf 2432 11 result result VBP cord-022526-j9kg00qf 2432 12 from from IN cord-022526-j9kg00qf 2432 13 dental dental JJ cord-022526-j9kg00qf 2432 14 impaction impaction NN cord-022526-j9kg00qf 2432 15 , , , cord-022526-j9kg00qf 2432 16 immature immature JJ cord-022526-j9kg00qf 2432 17 root root NN cord-022526-j9kg00qf 2432 18 structures structure NNS cord-022526-j9kg00qf 2432 19 make make VBP cord-022526-j9kg00qf 2432 20 achieving achieve VBG cord-022526-j9kg00qf 2432 21 an an DT cord-022526-j9kg00qf 2432 22 apical apical JJ cord-022526-j9kg00qf 2432 23 seal seal NN cord-022526-j9kg00qf 2432 24 of of IN cord-022526-j9kg00qf 2432 25 the the DT cord-022526-j9kg00qf 2432 26 exposed expose VBN cord-022526-j9kg00qf 2432 27 pulp pulp NN cord-022526-j9kg00qf 2432 28 difficult difficult JJ cord-022526-j9kg00qf 2432 29 . . . cord-022526-j9kg00qf 2433 1 Gingival gingival JJ cord-022526-j9kg00qf 2433 2 hyperemia hyperemia NN cord-022526-j9kg00qf 2433 3 and and CC cord-022526-j9kg00qf 2433 4 inflammation inflammation NN cord-022526-j9kg00qf 2433 5 occur occur VBP cord-022526-j9kg00qf 2433 6 during during IN cord-022526-j9kg00qf 2433 7 the the DT cord-022526-j9kg00qf 2433 8 eruption eruption NN cord-022526-j9kg00qf 2433 9 of of IN cord-022526-j9kg00qf 2433 10 the the DT cord-022526-j9kg00qf 2433 11 permanent permanent JJ cord-022526-j9kg00qf 2433 12 teeth tooth NNS cord-022526-j9kg00qf 2433 13 and and CC cord-022526-j9kg00qf 2433 14 are be VBP cord-022526-j9kg00qf 2433 15 common common JJ cord-022526-j9kg00qf 2433 16 causes cause NNS cord-022526-j9kg00qf 2433 17 of of IN cord-022526-j9kg00qf 2433 18 a a DT cord-022526-j9kg00qf 2433 19 sore sore JJ cord-022526-j9kg00qf 2433 20 mouth mouth NN cord-022526-j9kg00qf 2433 21 in in IN cord-022526-j9kg00qf 2433 22 young young JJ cord-022526-j9kg00qf 2433 23 horses horse NNS cord-022526-j9kg00qf 2433 24 ( ( -LRB- cord-022526-j9kg00qf 2433 25 particularly particularly RB cord-022526-j9kg00qf 2433 26 3-year 3-year CD cord-022526-j9kg00qf 2433 27 - - HYPH cord-022526-j9kg00qf 2433 28 olds old NNS cord-022526-j9kg00qf 2433 29 as as IN cord-022526-j9kg00qf 2433 30 the the DT cord-022526-j9kg00qf 2433 31 first first JJ cord-022526-j9kg00qf 2433 32 dental dental JJ cord-022526-j9kg00qf 2433 33 caps cap NNS cord-022526-j9kg00qf 2433 34 loosen loosen VBP cord-022526-j9kg00qf 2433 35 ) ) -RRB- cord-022526-j9kg00qf 2433 36 . . . cord-022526-j9kg00qf 2434 1 Such such JJ cord-022526-j9kg00qf 2434 2 periodontal periodontal JJ cord-022526-j9kg00qf 2434 3 changes change NNS cord-022526-j9kg00qf 2434 4 usually usually RB cord-022526-j9kg00qf 2434 5 resolve resolve VB cord-022526-j9kg00qf 2434 6 as as IN cord-022526-j9kg00qf 2434 7 the the DT cord-022526-j9kg00qf 2434 8 permanent permanent JJ cord-022526-j9kg00qf 2434 9 dental dental JJ cord-022526-j9kg00qf 2434 10 arcade arcade NN cord-022526-j9kg00qf 2434 11 is be VBZ cord-022526-j9kg00qf 2434 12 established establish VBN cord-022526-j9kg00qf 2434 13 . . . cord-022526-j9kg00qf 2435 1 During during IN cord-022526-j9kg00qf 2435 2 normal normal JJ cord-022526-j9kg00qf 2435 3 mastication mastication NN cord-022526-j9kg00qf 2435 4 , , , cord-022526-j9kg00qf 2435 5 the the DT cord-022526-j9kg00qf 2435 6 shearing shearing NN cord-022526-j9kg00qf 2435 7 forces force NNS cord-022526-j9kg00qf 2435 8 generated generate VBN cord-022526-j9kg00qf 2435 9 by by IN cord-022526-j9kg00qf 2435 10 the the DT cord-022526-j9kg00qf 2435 11 occlusal occlusal NN cord-022526-j9kg00qf 2435 12 contact contact NN cord-022526-j9kg00qf 2435 13 of of IN cord-022526-j9kg00qf 2435 14 the the DT cord-022526-j9kg00qf 2435 15 cheek cheek NN cord-022526-j9kg00qf 2435 16 teeth tooth NNS cord-022526-j9kg00qf 2435 17 essentially essentially RB cord-022526-j9kg00qf 2435 18 clean clean VBP cord-022526-j9kg00qf 2435 19 the the DT cord-022526-j9kg00qf 2435 20 teeth tooth NNS cord-022526-j9kg00qf 2435 21 of of IN cord-022526-j9kg00qf 2435 22 plaque plaque NN cord-022526-j9kg00qf 2435 23 and and CC cord-022526-j9kg00qf 2435 24 effectively effectively RB cord-022526-j9kg00qf 2435 25 inhibit inhibit VB cord-022526-j9kg00qf 2435 26 deposition deposition NN cord-022526-j9kg00qf 2435 27 of of IN cord-022526-j9kg00qf 2435 28 dental dental JJ cord-022526-j9kg00qf 2435 29 calculus calculus NN cord-022526-j9kg00qf 2435 30 . . . cord-022526-j9kg00qf 2436 1 Wherever wherever WRB cord-022526-j9kg00qf 2436 2 occlusal occlusal NN cord-022526-j9kg00qf 2436 3 contact contact NN cord-022526-j9kg00qf 2436 4 is be VBZ cord-022526-j9kg00qf 2436 5 ineffective ineffective JJ cord-022526-j9kg00qf 2436 6 , , , cord-022526-j9kg00qf 2436 7 periodontal periodontal JJ cord-022526-j9kg00qf 2436 8 changes change NNS cord-022526-j9kg00qf 2436 9 and and CC cord-022526-j9kg00qf 2436 10 calculus calculus NN cord-022526-j9kg00qf 2436 11 buildup buildup NN cord-022526-j9kg00qf 2436 12 occur occur VBP cord-022526-j9kg00qf 2436 13 ; ; : cord-022526-j9kg00qf 2436 14 for for IN cord-022526-j9kg00qf 2436 15 example example NN cord-022526-j9kg00qf 2436 16 , , , cord-022526-j9kg00qf 2436 17 the the DT cord-022526-j9kg00qf 2436 18 deposition deposition NN cord-022526-j9kg00qf 2436 19 of of IN cord-022526-j9kg00qf 2436 20 calculus calculus NN cord-022526-j9kg00qf 2436 21 on on IN cord-022526-j9kg00qf 2436 22 the the DT cord-022526-j9kg00qf 2436 23 canine canine JJ cord-022526-j9kg00qf 2436 24 teeth tooth NNS cord-022526-j9kg00qf 2436 25 of of IN cord-022526-j9kg00qf 2436 26 mature mature JJ cord-022526-j9kg00qf 2436 27 geldings gelding NNS cord-022526-j9kg00qf 2436 28 and and CC cord-022526-j9kg00qf 2436 29 stallions stallion NNS cord-022526-j9kg00qf 2436 30 is be VBZ cord-022526-j9kg00qf 2436 31 common common JJ cord-022526-j9kg00qf 2436 32 . . . cord-022526-j9kg00qf 2437 1 Routine routine JJ cord-022526-j9kg00qf 2437 2 dental dental JJ cord-022526-j9kg00qf 2437 3 prophylaxis prophylaxis NN cord-022526-j9kg00qf 2437 4 forms form VBZ cord-022526-j9kg00qf 2437 5 an an DT cord-022526-j9kg00qf 2437 6 important important JJ cord-022526-j9kg00qf 2437 7 component component NN cord-022526-j9kg00qf 2437 8 of of IN cord-022526-j9kg00qf 2437 9 maintaining maintain VBG cord-022526-j9kg00qf 2437 10 normal normal JJ cord-022526-j9kg00qf 2437 11 occlusal occlusal NN cord-022526-j9kg00qf 2437 12 contact contact NN cord-022526-j9kg00qf 2437 13 , , , cord-022526-j9kg00qf 2437 14 and and CC cord-022526-j9kg00qf 2437 15 for for IN cord-022526-j9kg00qf 2437 16 this this DT cord-022526-j9kg00qf 2437 17 reason reason NN cord-022526-j9kg00qf 2437 18 one one PRP cord-022526-j9kg00qf 2437 19 should should MD cord-022526-j9kg00qf 2437 20 remove remove VB cord-022526-j9kg00qf 2437 21 arcade arcade NN cord-022526-j9kg00qf 2437 22 irregularities irregularity NNS cord-022526-j9kg00qf 2437 23 that that WDT cord-022526-j9kg00qf 2437 24 result result VBP cord-022526-j9kg00qf 2437 25 in in IN cord-022526-j9kg00qf 2437 26 enamel enamel NN cord-022526-j9kg00qf 2437 27 point point NN cord-022526-j9kg00qf 2437 28 formation formation NN cord-022526-j9kg00qf 2437 29 on on IN cord-022526-j9kg00qf 2437 30 the the DT cord-022526-j9kg00qf 2437 31 buccal buccal JJ cord-022526-j9kg00qf 2437 32 edges edge NNS cord-022526-j9kg00qf 2437 33 of of IN cord-022526-j9kg00qf 2437 34 the the DT cord-022526-j9kg00qf 2437 35 maxillary maxillary JJ cord-022526-j9kg00qf 2437 36 cheek cheek NN cord-022526-j9kg00qf 2437 37 teeth tooth NNS cord-022526-j9kg00qf 2437 38 and and CC cord-022526-j9kg00qf 2437 39 the the DT cord-022526-j9kg00qf 2437 40 lingual lingual JJ cord-022526-j9kg00qf 2437 41 edges edge NNS cord-022526-j9kg00qf 2437 42 of of IN cord-022526-j9kg00qf 2437 43 the the DT cord-022526-j9kg00qf 2437 44 mandibular mandibular JJ cord-022526-j9kg00qf 2437 45 cheek cheek NN cord-022526-j9kg00qf 2437 46 teeth tooth NNS cord-022526-j9kg00qf 2437 47 . . . cord-022526-j9kg00qf 2438 1 One one PRP cord-022526-j9kg00qf 2438 2 should should MD cord-022526-j9kg00qf 2438 3 remove remove VB cord-022526-j9kg00qf 2438 4 these these DT cord-022526-j9kg00qf 2438 5 edges edge NNS cord-022526-j9kg00qf 2438 6 annually annually RB cord-022526-j9kg00qf 2438 7 in in IN cord-022526-j9kg00qf 2438 8 horses horse NNS cord-022526-j9kg00qf 2438 9 that that WDT cord-022526-j9kg00qf 2438 10 are be VBP cord-022526-j9kg00qf 2438 11 at at IN cord-022526-j9kg00qf 2438 12 grass grass NN cord-022526-j9kg00qf 2438 13 and and CC cord-022526-j9kg00qf 2438 14 twice twice RB cord-022526-j9kg00qf 2438 15 yearly yearly JJ cord-022526-j9kg00qf 2438 16 in in IN cord-022526-j9kg00qf 2438 17 young young JJ cord-022526-j9kg00qf 2438 18 horses horse NNS cord-022526-j9kg00qf 2438 19 , , , cord-022526-j9kg00qf 2438 20 aged aged JJ cord-022526-j9kg00qf 2438 21 horses horse NNS cord-022526-j9kg00qf 2438 22 , , , cord-022526-j9kg00qf 2438 23 and and CC cord-022526-j9kg00qf 2438 24 stabled stable VBD cord-022526-j9kg00qf 2438 25 horses horse NNS cord-022526-j9kg00qf 2438 26 . . . cord-022526-j9kg00qf 2439 1 Horses horse NNS cord-022526-j9kg00qf 2439 2 at at IN cord-022526-j9kg00qf 2439 3 grass grass NN cord-022526-j9kg00qf 2439 4 have have VBP cord-022526-j9kg00qf 2439 5 been be VBN cord-022526-j9kg00qf 2439 6 shown show VBN cord-022526-j9kg00qf 2439 7 to to TO cord-022526-j9kg00qf 2439 8 have have VB cord-022526-j9kg00qf 2439 9 a a DT cord-022526-j9kg00qf 2439 10 greater great JJR cord-022526-j9kg00qf 2439 11 range range NN cord-022526-j9kg00qf 2439 12 of of IN cord-022526-j9kg00qf 2439 13 occlusal occlusal NN cord-022526-j9kg00qf 2439 14 contact contact NN cord-022526-j9kg00qf 2439 15 and and CC cord-022526-j9kg00qf 2439 16 therefore therefore RB cord-022526-j9kg00qf 2439 17 better well JJR cord-022526-j9kg00qf 2439 18 periodontal periodontal JJ cord-022526-j9kg00qf 2439 19 hygiene hygiene NN cord-022526-j9kg00qf 2439 20 than than IN cord-022526-j9kg00qf 2439 21 stabled stabled JJ cord-022526-j9kg00qf 2439 22 horses horse NNS cord-022526-j9kg00qf 2439 23 . . . cord-022526-j9kg00qf 2440 1 In in IN cord-022526-j9kg00qf 2440 2 stabled stabled JJ cord-022526-j9kg00qf 2440 3 horses horse NNS cord-022526-j9kg00qf 2440 4 the the DT cord-022526-j9kg00qf 2440 5 range range NN cord-022526-j9kg00qf 2440 6 of of IN cord-022526-j9kg00qf 2440 7 occlusal occlusal NN cord-022526-j9kg00qf 2440 8 contact contact NN cord-022526-j9kg00qf 2440 9 is be VBZ cord-022526-j9kg00qf 2440 10 narrower narrow JJR cord-022526-j9kg00qf 2440 11 and and CC cord-022526-j9kg00qf 2440 12 the the DT cord-022526-j9kg00qf 2440 13 formation formation NN cord-022526-j9kg00qf 2440 14 of of IN cord-022526-j9kg00qf 2440 15 enamel enamel JJ cord-022526-j9kg00qf 2440 16 points point NNS cord-022526-j9kg00qf 2440 17 occurs occur VBZ cord-022526-j9kg00qf 2440 18 more more RBR cord-022526-j9kg00qf 2440 19 frequently frequently RB cord-022526-j9kg00qf 2440 20 with with IN cord-022526-j9kg00qf 2440 21 subsequent subsequent JJ cord-022526-j9kg00qf 2440 22 buccal buccal JJ cord-022526-j9kg00qf 2440 23 ulceration ulceration NN cord-022526-j9kg00qf 2440 24 and and CC cord-022526-j9kg00qf 2440 25 the the DT cord-022526-j9kg00qf 2440 26 initiation initiation NN cord-022526-j9kg00qf 2440 27 of of IN cord-022526-j9kg00qf 2440 28 a a DT cord-022526-j9kg00qf 2440 29 cycle cycle NN cord-022526-j9kg00qf 2440 30 of of IN cord-022526-j9kg00qf 2440 31 altered alter VBN cord-022526-j9kg00qf 2440 32 occlusal occlusal NN cord-022526-j9kg00qf 2440 33 contact contact NN cord-022526-j9kg00qf 2440 34 and and CC cord-022526-j9kg00qf 2440 35 hence hence RB cord-022526-j9kg00qf 2440 36 irregular irregular JJ cord-022526-j9kg00qf 2440 37 arcade arcade NN cord-022526-j9kg00qf 2440 38 formation formation NN cord-022526-j9kg00qf 2440 39 . . . cord-022526-j9kg00qf 2441 1 This this DT cord-022526-j9kg00qf 2441 2 process process NN cord-022526-j9kg00qf 2441 3 leads lead VBZ cord-022526-j9kg00qf 2441 4 to to IN cord-022526-j9kg00qf 2441 5 severe severe JJ cord-022526-j9kg00qf 2441 6 forms form NNS cord-022526-j9kg00qf 2441 7 of of IN cord-022526-j9kg00qf 2441 8 periodontal periodontal JJ cord-022526-j9kg00qf 2441 9 disease disease NN cord-022526-j9kg00qf 2441 10 and and CC cord-022526-j9kg00qf 2441 11 wave wave VB cord-022526-j9kg00qf 2441 12 mouth mouth NN cord-022526-j9kg00qf 2441 13 formation formation NN cord-022526-j9kg00qf 2441 14 . . . cord-022526-j9kg00qf 2442 1 Periodontal periodontal JJ cord-022526-j9kg00qf 2442 2 disease disease NN cord-022526-j9kg00qf 2442 3 occurs occur VBZ cord-022526-j9kg00qf 2442 4 with with IN cord-022526-j9kg00qf 2442 5 abnormal abnormal JJ cord-022526-j9kg00qf 2442 6 occlusal occlusal NN cord-022526-j9kg00qf 2442 7 contact contact NN cord-022526-j9kg00qf 2442 8 and and CC cord-022526-j9kg00qf 2442 9 initiation initiation NN cord-022526-j9kg00qf 2442 10 of of IN cord-022526-j9kg00qf 2442 11 the the DT cord-022526-j9kg00qf 2442 12 cycle cycle NN cord-022526-j9kg00qf 2442 13 of of IN cord-022526-j9kg00qf 2442 14 irregular irregular JJ cord-022526-j9kg00qf 2442 15 wear wear NN cord-022526-j9kg00qf 2442 16 and and CC cord-022526-j9kg00qf 2442 17 abnormal abnormal JJ cord-022526-j9kg00qf 2442 18 contact contact NN cord-022526-j9kg00qf 2442 19 . . . cord-022526-j9kg00qf 2443 1 Such such JJ cord-022526-j9kg00qf 2443 2 changes change NNS cord-022526-j9kg00qf 2443 3 progress progress VBP cord-022526-j9kg00qf 2443 4 to to IN cord-022526-j9kg00qf 2443 5 loss loss NN cord-022526-j9kg00qf 2443 6 of of IN cord-022526-j9kg00qf 2443 7 alveolar alveolar JJ cord-022526-j9kg00qf 2443 8 bone bone NN cord-022526-j9kg00qf 2443 9 , , , cord-022526-j9kg00qf 2443 10 gross gross JJ cord-022526-j9kg00qf 2443 11 periodontal periodontal JJ cord-022526-j9kg00qf 2443 12 sepsis sepsis NN cord-022526-j9kg00qf 2443 13 , , , cord-022526-j9kg00qf 2443 14 and and CC cord-022526-j9kg00qf 2443 15 loss loss NN cord-022526-j9kg00qf 2443 16 of of IN cord-022526-j9kg00qf 2443 17 tooth tooth NN cord-022526-j9kg00qf 2443 18 support support NN cord-022526-j9kg00qf 2443 19 . . . cord-022526-j9kg00qf 2444 1 In in IN cord-022526-j9kg00qf 2444 2 this this DT cord-022526-j9kg00qf 2444 3 sense sense NN cord-022526-j9kg00qf 2444 4 periodontal periodontal JJ cord-022526-j9kg00qf 2444 5 disease disease NN cord-022526-j9kg00qf 2444 6 truly truly RB cord-022526-j9kg00qf 2444 7 is be VBZ cord-022526-j9kg00qf 2444 8 the the DT cord-022526-j9kg00qf 2444 9 scourge scourge NN cord-022526-j9kg00qf 2444 10 of of IN cord-022526-j9kg00qf 2444 11 the the DT cord-022526-j9kg00qf 2444 12 equine equine JJ cord-022526-j9kg00qf 2444 13 mouth mouth NN cord-022526-j9kg00qf 2444 14 and and CC cord-022526-j9kg00qf 2444 15 results result NNS cord-022526-j9kg00qf 2444 16 in in IN cord-022526-j9kg00qf 2444 17 tooth tooth NN cord-022526-j9kg00qf 2444 18 loss loss NN cord-022526-j9kg00qf 2444 19 . . . cord-022526-j9kg00qf 2445 1 13 13 CD cord-022526-j9kg00qf 2445 2 Palatine Palatine NNP cord-022526-j9kg00qf 2445 3 clefts cleft NNS cord-022526-j9kg00qf 2445 4 may may MD cord-022526-j9kg00qf 2445 5 result result VB cord-022526-j9kg00qf 2445 6 from from IN cord-022526-j9kg00qf 2445 7 an an DT cord-022526-j9kg00qf 2445 8 inherited inherit VBN cord-022526-j9kg00qf 2445 9 defect defect NN cord-022526-j9kg00qf 2445 10 and and CC cord-022526-j9kg00qf 2445 11 are be VBP cord-022526-j9kg00qf 2445 12 caused cause VBN cord-022526-j9kg00qf 2445 13 by by IN cord-022526-j9kg00qf 2445 14 failure failure NN cord-022526-j9kg00qf 2445 15 of of IN cord-022526-j9kg00qf 2445 16 the the DT cord-022526-j9kg00qf 2445 17 transverse transverse JJ cord-022526-j9kg00qf 2445 18 palatal palatal JJ cord-022526-j9kg00qf 2445 19 folds fold NNS cord-022526-j9kg00qf 2445 20 to to TO cord-022526-j9kg00qf 2445 21 fuse fuse VB cord-022526-j9kg00qf 2445 22 in in IN cord-022526-j9kg00qf 2445 23 the the DT cord-022526-j9kg00qf 2445 24 oral oral JJ cord-022526-j9kg00qf 2445 25 cavity cavity NN cord-022526-j9kg00qf 2445 26 . . . cord-022526-j9kg00qf 2446 1 Harelip Harelip NNP cord-022526-j9kg00qf 2446 2 accompanies accompany VBZ cord-022526-j9kg00qf 2446 3 few few JJ cord-022526-j9kg00qf 2446 4 palatine palatine NNP cord-022526-j9kg00qf 2446 5 clefts cleft NNS cord-022526-j9kg00qf 2446 6 in in IN cord-022526-j9kg00qf 2446 7 the the DT cord-022526-j9kg00qf 2446 8 horse horse NN cord-022526-j9kg00qf 2446 9 . . . cord-022526-j9kg00qf 2447 1 The the DT cord-022526-j9kg00qf 2447 2 degree degree NN cord-022526-j9kg00qf 2447 3 of of IN cord-022526-j9kg00qf 2447 4 palatine palatine NNP cord-022526-j9kg00qf 2447 5 clefting clefting NN cord-022526-j9kg00qf 2447 6 depends depend VBZ cord-022526-j9kg00qf 2447 7 on on IN cord-022526-j9kg00qf 2447 8 the the DT cord-022526-j9kg00qf 2447 9 stage stage NN cord-022526-j9kg00qf 2447 10 at at IN cord-022526-j9kg00qf 2447 11 which which WDT cord-022526-j9kg00qf 2447 12 interruption interruption NN cord-022526-j9kg00qf 2447 13 in in IN cord-022526-j9kg00qf 2447 14 the the DT cord-022526-j9kg00qf 2447 15 fusion fusion NN cord-022526-j9kg00qf 2447 16 of of IN cord-022526-j9kg00qf 2447 17 the the DT cord-022526-j9kg00qf 2447 18 852 852 CD cord-022526-j9kg00qf 2447 19 PART PART NNP cord-022526-j9kg00qf 2447 20 II II NNP cord-022526-j9kg00qf 2447 21 Disorders disorder NNS cord-022526-j9kg00qf 2447 22 of of IN cord-022526-j9kg00qf 2447 23 Specific specific JJ cord-022526-j9kg00qf 2447 24 Body Body NNP cord-022526-j9kg00qf 2447 25 Systems Systems NNPS cord-022526-j9kg00qf 2447 26 caries carie NNS cord-022526-j9kg00qf 2447 27 of of IN cord-022526-j9kg00qf 2447 28 cementum cementum NN cord-022526-j9kg00qf 2447 29 occurs occur VBZ cord-022526-j9kg00qf 2447 30 , , , cord-022526-j9kg00qf 2447 31 that that RB cord-022526-j9kg00qf 2447 32 is is RB cord-022526-j9kg00qf 2447 33 , , , cord-022526-j9kg00qf 2447 34 secondary secondary JJ cord-022526-j9kg00qf 2447 35 inflammatory inflammatory JJ cord-022526-j9kg00qf 2447 36 disease disease NN cord-022526-j9kg00qf 2447 37 and and CC cord-022526-j9kg00qf 2447 38 acid acid JJ cord-022526-j9kg00qf 2447 39 necrosis necrosis NN cord-022526-j9kg00qf 2447 40 of of IN cord-022526-j9kg00qf 2447 41 the the DT cord-022526-j9kg00qf 2447 42 cementum cementum NN cord-022526-j9kg00qf 2447 43 , , , cord-022526-j9kg00qf 2447 44 apical apical JJ cord-022526-j9kg00qf 2447 45 osteitis osteitis NN cord-022526-j9kg00qf 2447 46 may may MD cord-022526-j9kg00qf 2447 47 develop develop VB cord-022526-j9kg00qf 2447 48 . . . cord-022526-j9kg00qf 2448 1 Pulpitis Pulpitis NNP cord-022526-j9kg00qf 2448 2 is be VBZ cord-022526-j9kg00qf 2448 3 key key JJ cord-022526-j9kg00qf 2448 4 to to IN cord-022526-j9kg00qf 2448 5 the the DT cord-022526-j9kg00qf 2448 6 pathogenesis pathogenesis NN cord-022526-j9kg00qf 2448 7 of of IN cord-022526-j9kg00qf 2448 8 dental dental JJ cord-022526-j9kg00qf 2448 9 decay decay NN cord-022526-j9kg00qf 2448 10 in in IN cord-022526-j9kg00qf 2448 11 the the DT cord-022526-j9kg00qf 2448 12 horse horse NN cord-022526-j9kg00qf 2448 13 . . . cord-022526-j9kg00qf 2449 1 The the DT cord-022526-j9kg00qf 2449 2 initiation initiation NN cord-022526-j9kg00qf 2449 3 of of IN cord-022526-j9kg00qf 2449 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 2449 5 pulp pulp NN cord-022526-j9kg00qf 2449 6 changes change NNS cord-022526-j9kg00qf 2449 7 may may MD cord-022526-j9kg00qf 2449 8 be be VB cord-022526-j9kg00qf 2449 9 a a DT cord-022526-j9kg00qf 2449 10 sequela sequela NN cord-022526-j9kg00qf 2449 11 to to IN cord-022526-j9kg00qf 2449 12 dental dental JJ cord-022526-j9kg00qf 2449 13 impaction impaction NN cord-022526-j9kg00qf 2449 14 or or CC cord-022526-j9kg00qf 2449 15 dental dental JJ cord-022526-j9kg00qf 2449 16 caries carie NNS cord-022526-j9kg00qf 2449 17 or or CC cord-022526-j9kg00qf 2449 18 may may MD cord-022526-j9kg00qf 2449 19 result result VB cord-022526-j9kg00qf 2449 20 from from IN cord-022526-j9kg00qf 2449 21 fracture fracture NN cord-022526-j9kg00qf 2449 22 of of IN cord-022526-j9kg00qf 2449 23 a a DT cord-022526-j9kg00qf 2449 24 tooth tooth NN cord-022526-j9kg00qf 2449 25 . . . cord-022526-j9kg00qf 2450 1 If if IN cord-022526-j9kg00qf 2450 2 the the DT cord-022526-j9kg00qf 2450 3 onset onset NN cord-022526-j9kg00qf 2450 4 of of IN cord-022526-j9kg00qf 2450 5 the the DT cord-022526-j9kg00qf 2450 6 inflammatory inflammatory JJ cord-022526-j9kg00qf 2450 7 process process NN cord-022526-j9kg00qf 2450 8 is be VBZ cord-022526-j9kg00qf 2450 9 slow slow JJ cord-022526-j9kg00qf 2450 10 , , , cord-022526-j9kg00qf 2450 11 then then RB cord-022526-j9kg00qf 2450 12 formation formation NN cord-022526-j9kg00qf 2450 13 of of IN cord-022526-j9kg00qf 2450 14 secondary secondary JJ cord-022526-j9kg00qf 2450 15 dentin dentin NN cord-022526-j9kg00qf 2450 16 within within IN cord-022526-j9kg00qf 2450 17 the the DT cord-022526-j9kg00qf 2450 18 pulp pulp NN cord-022526-j9kg00qf 2450 19 chambers chamber NNS cord-022526-j9kg00qf 2450 20 may may MD cord-022526-j9kg00qf 2450 21 protect protect VB cord-022526-j9kg00qf 2450 22 the the DT cord-022526-j9kg00qf 2450 23 pulp pulp NN cord-022526-j9kg00qf 2450 24 and and CC cord-022526-j9kg00qf 2450 25 the the DT cord-022526-j9kg00qf 2450 26 tooth tooth NN cord-022526-j9kg00qf 2450 27 . . . cord-022526-j9kg00qf 2451 1 Secondary secondary JJ cord-022526-j9kg00qf 2451 2 dentin dentin NN cord-022526-j9kg00qf 2451 3 formation formation NN cord-022526-j9kg00qf 2451 4 occurs occur VBZ cord-022526-j9kg00qf 2451 5 from from IN cord-022526-j9kg00qf 2451 6 stimulation stimulation NN cord-022526-j9kg00qf 2451 7 of of IN cord-022526-j9kg00qf 2451 8 odontoblasts odontoblast NNS cord-022526-j9kg00qf 2451 9 within within IN cord-022526-j9kg00qf 2451 10 the the DT cord-022526-j9kg00qf 2451 11 pulp pulp NN cord-022526-j9kg00qf 2451 12 chamber chamber NN cord-022526-j9kg00qf 2451 13 . . . cord-022526-j9kg00qf 2452 1 Such such JJ cord-022526-j9kg00qf 2452 2 changes change NNS cord-022526-j9kg00qf 2452 3 are be VBP cord-022526-j9kg00qf 2452 4 the the DT cord-022526-j9kg00qf 2452 5 normal normal JJ cord-022526-j9kg00qf 2452 6 process process NN cord-022526-j9kg00qf 2452 7 of of IN cord-022526-j9kg00qf 2452 8 protection protection NN cord-022526-j9kg00qf 2452 9 during during IN cord-022526-j9kg00qf 2452 10 dental dental JJ cord-022526-j9kg00qf 2452 11 wear wear NN cord-022526-j9kg00qf 2452 12 and and CC cord-022526-j9kg00qf 2452 13 attrition attrition NN cord-022526-j9kg00qf 2452 14 as as IN cord-022526-j9kg00qf 2452 15 crown crown NN cord-022526-j9kg00qf 2452 16 substances substance NNS cord-022526-j9kg00qf 2452 17 wear wear VBP cord-022526-j9kg00qf 2452 18 away away RB cord-022526-j9kg00qf 2452 19 and and CC cord-022526-j9kg00qf 2452 20 the the DT cord-022526-j9kg00qf 2452 21 reserve reserve NN cord-022526-j9kg00qf 2452 22 crown crown NN cord-022526-j9kg00qf 2452 23 comes come VBZ cord-022526-j9kg00qf 2452 24 into into IN cord-022526-j9kg00qf 2452 25 wear wear NN cord-022526-j9kg00qf 2452 26 . . . cord-022526-j9kg00qf 2453 1 In in IN cord-022526-j9kg00qf 2453 2 acute acute JJ cord-022526-j9kg00qf 2453 3 disease disease NN cord-022526-j9kg00qf 2453 4 , , , cord-022526-j9kg00qf 2453 5 however however RB cord-022526-j9kg00qf 2453 6 , , , cord-022526-j9kg00qf 2453 7 this this DT cord-022526-j9kg00qf 2453 8 defense defense NN cord-022526-j9kg00qf 2453 9 mechanism mechanism NN cord-022526-j9kg00qf 2453 10 is be VBZ cord-022526-j9kg00qf 2453 11 ineffective ineffective JJ cord-022526-j9kg00qf 2453 12 , , , cord-022526-j9kg00qf 2453 13 and and CC cord-022526-j9kg00qf 2453 14 the the DT cord-022526-j9kg00qf 2453 15 changes change NNS cord-022526-j9kg00qf 2453 16 that that WDT cord-022526-j9kg00qf 2453 17 occur occur VBP cord-022526-j9kg00qf 2454 1 and and CC cord-022526-j9kg00qf 2454 2 that that DT cord-022526-j9kg00qf 2454 3 are be VBP cord-022526-j9kg00qf 2454 4 sequelae sequelae JJ cord-022526-j9kg00qf 2454 5 to to IN cord-022526-j9kg00qf 2454 6 pulpitis pulpitis NN cord-022526-j9kg00qf 2455 1 reflect reflect VB cord-022526-j9kg00qf 2455 2 the the DT cord-022526-j9kg00qf 2455 3 location location NN cord-022526-j9kg00qf 2455 4 of of IN cord-022526-j9kg00qf 2455 5 each each DT cord-022526-j9kg00qf 2455 6 affected affect VBN cord-022526-j9kg00qf 2455 7 tooth tooth NN cord-022526-j9kg00qf 2455 8 . . . cord-022526-j9kg00qf 2456 1 For for IN cord-022526-j9kg00qf 2456 2 example example NN cord-022526-j9kg00qf 2456 3 , , , cord-022526-j9kg00qf 2456 4 pulpitis pulpitis NN cord-022526-j9kg00qf 2456 5 and and CC cord-022526-j9kg00qf 2456 6 apical apical JJ cord-022526-j9kg00qf 2456 7 osteitis osteitis NN cord-022526-j9kg00qf 2456 8 of of IN cord-022526-j9kg00qf 2456 9 the the DT cord-022526-j9kg00qf 2456 10 third third JJ cord-022526-j9kg00qf 2456 11 mandibular mandibular JJ cord-022526-j9kg00qf 2456 12 cheek cheek NN cord-022526-j9kg00qf 2456 13 tooth tooth NN cord-022526-j9kg00qf 2456 14 most most RBS cord-022526-j9kg00qf 2456 15 commonly commonly RB cord-022526-j9kg00qf 2456 16 results result NNS cord-022526-j9kg00qf 2456 17 in in IN cord-022526-j9kg00qf 2456 18 the the DT cord-022526-j9kg00qf 2456 19 development development NN cord-022526-j9kg00qf 2456 20 of of IN cord-022526-j9kg00qf 2456 21 a a DT cord-022526-j9kg00qf 2456 22 mandibular mandibular JJ cord-022526-j9kg00qf 2456 23 dental dental JJ cord-022526-j9kg00qf 2456 24 fistula fistula NN cord-022526-j9kg00qf 2456 25 . . . cord-022526-j9kg00qf 2457 1 Pulpitis Pulpitis NNP cord-022526-j9kg00qf 2457 2 of of IN cord-022526-j9kg00qf 2457 3 the the DT cord-022526-j9kg00qf 2457 4 third third JJ cord-022526-j9kg00qf 2457 5 maxillary maxillary JJ cord-022526-j9kg00qf 2457 6 cheek cheek NN cord-022526-j9kg00qf 2457 7 tooth tooth NN cord-022526-j9kg00qf 2457 8 , , , cord-022526-j9kg00qf 2457 9 however however RB cord-022526-j9kg00qf 2457 10 , , , cord-022526-j9kg00qf 2457 11 results result VBZ cord-022526-j9kg00qf 2457 12 in in IN cord-022526-j9kg00qf 2457 13 an an DT cord-022526-j9kg00qf 2457 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 2457 15 disease disease NN cord-022526-j9kg00qf 2457 16 within within IN cord-022526-j9kg00qf 2457 17 the the DT cord-022526-j9kg00qf 2457 18 rostral rostral JJ cord-022526-j9kg00qf 2457 19 maxillary maxillary JJ cord-022526-j9kg00qf 2457 20 sinus sinus NN cord-022526-j9kg00qf 2457 21 and and CC cord-022526-j9kg00qf 2457 22 in in IN cord-022526-j9kg00qf 2457 23 development development NN cord-022526-j9kg00qf 2457 24 of of IN cord-022526-j9kg00qf 2457 25 chronic chronic JJ cord-022526-j9kg00qf 2457 26 maxillary maxillary JJ cord-022526-j9kg00qf 2457 27 sinus sinus NN cord-022526-j9kg00qf 2457 28 empyema empyema NN cord-022526-j9kg00qf 2458 1 ( ( -LRB- cord-022526-j9kg00qf 2458 2 Figure figure NN cord-022526-j9kg00qf 2458 3 13.8 13.8 CD cord-022526-j9kg00qf 2458 4 - - SYM cord-022526-j9kg00qf 2458 5 1 1 CD cord-022526-j9kg00qf 2458 6 ) ) -RRB- cord-022526-j9kg00qf 2458 7 . . . cord-022526-j9kg00qf 2459 1 Oblique oblique JJ cord-022526-j9kg00qf 2459 2 radiographs radiograph NNS cord-022526-j9kg00qf 2459 3 greatly greatly RB cord-022526-j9kg00qf 2459 4 assist assist VB cord-022526-j9kg00qf 2459 5 the the DT cord-022526-j9kg00qf 2459 6 diagnosis diagnosis NN cord-022526-j9kg00qf 2459 7 of of IN cord-022526-j9kg00qf 2459 8 dental dental JJ cord-022526-j9kg00qf 2459 9 decay decay NN cord-022526-j9kg00qf 2459 10 by by IN cord-022526-j9kg00qf 2459 11 demonstrating demonstrate VBG cord-022526-j9kg00qf 2459 12 sinus sinus NN cord-022526-j9kg00qf 2459 13 tract tract NN cord-022526-j9kg00qf 2459 14 formation formation NN cord-022526-j9kg00qf 2459 15 , , , cord-022526-j9kg00qf 2459 16 sequestration sequestration NN cord-022526-j9kg00qf 2459 17 of of IN cord-022526-j9kg00qf 2459 18 bone bone NN cord-022526-j9kg00qf 2459 19 , , , cord-022526-j9kg00qf 2459 20 mandibular mandibular JJ cord-022526-j9kg00qf 2459 21 osteitis osteitis NN cord-022526-j9kg00qf 2459 22 , , , cord-022526-j9kg00qf 2459 23 hyperplasia hyperplasia NN cord-022526-j9kg00qf 2459 24 of of IN cord-022526-j9kg00qf 2459 25 cementum cementum NN cord-022526-j9kg00qf 2459 26 , , , cord-022526-j9kg00qf 2459 27 and and CC cord-022526-j9kg00qf 2459 28 new new JJ cord-022526-j9kg00qf 2459 29 bone bone NN cord-022526-j9kg00qf 2459 30 formation formation NN cord-022526-j9kg00qf 2459 31 ( ( -LRB- cord-022526-j9kg00qf 2459 32 so so RB cord-022526-j9kg00qf 2459 33 - - HYPH cord-022526-j9kg00qf 2459 34 called call VBN cord-022526-j9kg00qf 2459 35 alveolar alveolar JJ cord-022526-j9kg00qf 2459 36 periosteitis periosteitis NNP cord-022526-j9kg00qf 2459 37 ) ) -RRB- cord-022526-j9kg00qf 2459 38 . . . cord-022526-j9kg00qf 2460 1 12 12 CD cord-022526-j9kg00qf 2461 1 The the DT cord-022526-j9kg00qf 2461 2 management management NN cord-022526-j9kg00qf 2461 3 of of IN cord-022526-j9kg00qf 2461 4 dental dental JJ cord-022526-j9kg00qf 2461 5 decay decay NN cord-022526-j9kg00qf 2461 6 in in IN cord-022526-j9kg00qf 2461 7 the the DT cord-022526-j9kg00qf 2461 8 horse horse NN cord-022526-j9kg00qf 2461 9 usually usually RB cord-022526-j9kg00qf 2461 10 involves involve VBZ cord-022526-j9kg00qf 2461 11 surgical surgical JJ cord-022526-j9kg00qf 2461 12 extraction extraction NN cord-022526-j9kg00qf 2461 13 of of IN cord-022526-j9kg00qf 2461 14 the the DT cord-022526-j9kg00qf 2461 15 diseased diseased JJ cord-022526-j9kg00qf 2461 16 tooth tooth NN cord-022526-j9kg00qf 2461 17 . . . cord-022526-j9kg00qf 2462 1 In in IN cord-022526-j9kg00qf 2462 2 some some DT cord-022526-j9kg00qf 2462 3 palatopalatal palatopalatal NN cord-022526-j9kg00qf 2462 4 folds fold NNS cord-022526-j9kg00qf 2462 5 occurs occur VBZ cord-022526-j9kg00qf 2462 6 . . . cord-022526-j9kg00qf 2463 1 Toxic toxic JJ cord-022526-j9kg00qf 2463 2 or or CC cord-022526-j9kg00qf 2463 3 teratogenic teratogenic JJ cord-022526-j9kg00qf 2463 4 effects effect NNS cord-022526-j9kg00qf 2463 5 are be VBP cord-022526-j9kg00qf 2463 6 documented document VBN cord-022526-j9kg00qf 2463 7 in in IN cord-022526-j9kg00qf 2463 8 other other JJ cord-022526-j9kg00qf 2463 9 species specie NNS cord-022526-j9kg00qf 2463 10 , , , cord-022526-j9kg00qf 2463 11 but but CC cord-022526-j9kg00qf 2463 12 little little JJ cord-022526-j9kg00qf 2463 13 data datum NNS cord-022526-j9kg00qf 2463 14 are be VBP cord-022526-j9kg00qf 2463 15 available available JJ cord-022526-j9kg00qf 2463 16 in in IN cord-022526-j9kg00qf 2463 17 the the DT cord-022526-j9kg00qf 2463 18 horse horse NN cord-022526-j9kg00qf 2463 19 . . . cord-022526-j9kg00qf 2464 1 In in IN cord-022526-j9kg00qf 2464 2 recent recent JJ cord-022526-j9kg00qf 2464 3 years year NNS cord-022526-j9kg00qf 2464 4 , , , cord-022526-j9kg00qf 2464 5 treatment treatment NN cord-022526-j9kg00qf 2464 6 for for IN cord-022526-j9kg00qf 2464 7 repair repair NN cord-022526-j9kg00qf 2464 8 of of IN cord-022526-j9kg00qf 2464 9 uncomplicated uncomplicated JJ cord-022526-j9kg00qf 2464 10 palatine palatine NNP cord-022526-j9kg00qf 2464 11 defects defect NNS cord-022526-j9kg00qf 2464 12 has have VBZ cord-022526-j9kg00qf 2464 13 been be VBN cord-022526-j9kg00qf 2464 14 recommended recommend VBN cord-022526-j9kg00qf 2464 15 but but CC cord-022526-j9kg00qf 2464 16 prognosis prognosis NN cord-022526-j9kg00qf 2464 17 is be VBZ cord-022526-j9kg00qf 2464 18 generally generally RB cord-022526-j9kg00qf 2464 19 poor poor JJ cord-022526-j9kg00qf 2464 20 because because IN cord-022526-j9kg00qf 2464 21 of of IN cord-022526-j9kg00qf 2464 22 the the DT cord-022526-j9kg00qf 2464 23 considerable considerable JJ cord-022526-j9kg00qf 2464 24 nursing nursing NN cord-022526-j9kg00qf 2464 25 care care NN cord-022526-j9kg00qf 2464 26 required require VBN cord-022526-j9kg00qf 2464 27 and and CC cord-022526-j9kg00qf 2464 28 the the DT cord-022526-j9kg00qf 2464 29 high high JJ cord-022526-j9kg00qf 2464 30 incidence incidence NN cord-022526-j9kg00qf 2464 31 of of IN cord-022526-j9kg00qf 2464 32 surgical surgical JJ cord-022526-j9kg00qf 2464 33 failures failure NNS cord-022526-j9kg00qf 2464 34 . . . cord-022526-j9kg00qf 2465 1 One one PRP cord-022526-j9kg00qf 2465 2 should should MD cord-022526-j9kg00qf 2465 3 emphasize emphasize VB cord-022526-j9kg00qf 2465 4 early early JJ cord-022526-j9kg00qf 2465 5 surgery surgery NN cord-022526-j9kg00qf 2465 6 and and CC cord-022526-j9kg00qf 2465 7 the the DT cord-022526-j9kg00qf 2465 8 use use NN cord-022526-j9kg00qf 2465 9 of of IN cord-022526-j9kg00qf 2465 10 mandibular mandibular JJ cord-022526-j9kg00qf 2465 11 symphysiotomy symphysiotomy NN cord-022526-j9kg00qf 2465 12 in in IN cord-022526-j9kg00qf 2465 13 affording afford VBG cord-022526-j9kg00qf 2465 14 surgical surgical JJ cord-022526-j9kg00qf 2465 15 exposure exposure NN cord-022526-j9kg00qf 2465 16 . . . cord-022526-j9kg00qf 2466 1 The the DT cord-022526-j9kg00qf 2466 2 combination combination NN cord-022526-j9kg00qf 2466 3 of of IN cord-022526-j9kg00qf 2466 4 mandibular mandibular JJ cord-022526-j9kg00qf 2466 5 symphysiotomy symphysiotomy NNP cord-022526-j9kg00qf 2466 6 and and CC cord-022526-j9kg00qf 2466 7 transhyoid transhyoid NNP cord-022526-j9kg00qf 2466 8 pharyngotomy pharyngotomy NNP cord-022526-j9kg00qf 2466 9 to to TO cord-022526-j9kg00qf 2466 10 approach approach VB cord-022526-j9kg00qf 2466 11 the the DT cord-022526-j9kg00qf 2466 12 caudal caudal JJ cord-022526-j9kg00qf 2466 13 margins margin NNS cord-022526-j9kg00qf 2466 14 of of IN cord-022526-j9kg00qf 2466 15 the the DT cord-022526-j9kg00qf 2466 16 soft soft JJ cord-022526-j9kg00qf 2466 17 palate palate NN cord-022526-j9kg00qf 2466 18 affords afford VBZ cord-022526-j9kg00qf 2466 19 surgical surgical JJ cord-022526-j9kg00qf 2466 20 access access NN cord-022526-j9kg00qf 2466 21 , , , cord-022526-j9kg00qf 2466 22 and and CC cord-022526-j9kg00qf 2466 23 one one PRP cord-022526-j9kg00qf 2466 24 can can MD cord-022526-j9kg00qf 2466 25 construct construct VB cord-022526-j9kg00qf 2466 26 mucosal mucosal JJ cord-022526-j9kg00qf 2466 27 flaps flap NNS cord-022526-j9kg00qf 2466 28 to to TO cord-022526-j9kg00qf 2466 29 repair repair VB cord-022526-j9kg00qf 2466 30 the the DT cord-022526-j9kg00qf 2466 31 defects defect NNS cord-022526-j9kg00qf 2466 32 . . . cord-022526-j9kg00qf 2467 1 However however RB cord-022526-j9kg00qf 2467 2 , , , cord-022526-j9kg00qf 2467 3 the the DT cord-022526-j9kg00qf 2467 4 incidence incidence NN cord-022526-j9kg00qf 2467 5 of of IN cord-022526-j9kg00qf 2467 6 surgical surgical JJ cord-022526-j9kg00qf 2467 7 breakdown breakdown NN cord-022526-j9kg00qf 2467 8 is be VBZ cord-022526-j9kg00qf 2467 9 high high JJ cord-022526-j9kg00qf 2467 10 , , , cord-022526-j9kg00qf 2467 11 and and CC cord-022526-j9kg00qf 2467 12 healing healing NN cord-022526-j9kg00qf 2467 13 by by IN cord-022526-j9kg00qf 2467 14 first first JJ cord-022526-j9kg00qf 2467 15 intention intention NN cord-022526-j9kg00qf 2467 16 is be VBZ cord-022526-j9kg00qf 2467 17 the the DT cord-022526-j9kg00qf 2467 18 exception exception NN cord-022526-j9kg00qf 2467 19 rather rather RB cord-022526-j9kg00qf 2467 20 than than IN cord-022526-j9kg00qf 2467 21 the the DT cord-022526-j9kg00qf 2467 22 rule rule NN cord-022526-j9kg00qf 2467 23 . . . cord-022526-j9kg00qf 2468 1 A a DT cord-022526-j9kg00qf 2468 2 recent recent JJ cord-022526-j9kg00qf 2468 3 surgical surgical JJ cord-022526-j9kg00qf 2468 4 report report NN cord-022526-j9kg00qf 2468 5 documented document VBD cord-022526-j9kg00qf 2468 6 the the DT cord-022526-j9kg00qf 2468 7 successful successful JJ cord-022526-j9kg00qf 2468 8 closure closure NN cord-022526-j9kg00qf 2468 9 of of IN cord-022526-j9kg00qf 2468 10 a a DT cord-022526-j9kg00qf 2468 11 median median JJ cord-022526-j9kg00qf 2468 12 cleft cleft NN cord-022526-j9kg00qf 2468 13 of of IN cord-022526-j9kg00qf 2468 14 the the DT cord-022526-j9kg00qf 2468 15 lower low JJR cord-022526-j9kg00qf 2468 16 lip lip NN cord-022526-j9kg00qf 2468 17 and and CC cord-022526-j9kg00qf 2468 18 mandible mandible NN cord-022526-j9kg00qf 2468 19 in in IN cord-022526-j9kg00qf 2468 20 a a DT cord-022526-j9kg00qf 2468 21 donkey donkey NN cord-022526-j9kg00qf 2468 22 . . . cord-022526-j9kg00qf 2469 1 14 14 CD cord-022526-j9kg00qf 2469 2 Foals foal NNS cord-022526-j9kg00qf 2469 3 born bear VBN cord-022526-j9kg00qf 2469 4 with with IN cord-022526-j9kg00qf 2469 5 a a DT cord-022526-j9kg00qf 2469 6 severely severely RB cord-022526-j9kg00qf 2469 7 deviated deviate VBN cord-022526-j9kg00qf 2469 8 premaxilla premaxilla NN cord-022526-j9kg00qf 2469 9 and and CC cord-022526-j9kg00qf 2469 10 palate palate NN cord-022526-j9kg00qf 2469 11 have have VBP cord-022526-j9kg00qf 2469 12 a a DT cord-022526-j9kg00qf 2469 13 wry wry JJ cord-022526-j9kg00qf 2469 14 nose nose NN cord-022526-j9kg00qf 2469 15 . . . cord-022526-j9kg00qf 2470 1 One one PRP cord-022526-j9kg00qf 2470 2 can can MD cord-022526-j9kg00qf 2470 3 achieve achieve VB cord-022526-j9kg00qf 2470 4 surgical surgical JJ cord-022526-j9kg00qf 2470 5 correction correction NN cord-022526-j9kg00qf 2470 6 of of IN cord-022526-j9kg00qf 2470 7 the the DT cord-022526-j9kg00qf 2470 8 deviated deviate VBN cord-022526-j9kg00qf 2470 9 premaxilla premaxilla NN cord-022526-j9kg00qf 2470 10 by by IN cord-022526-j9kg00qf 2470 11 submucosal submucosal NNP cord-022526-j9kg00qf 2470 12 division division NN cord-022526-j9kg00qf 2470 13 of of IN cord-022526-j9kg00qf 2470 14 the the DT cord-022526-j9kg00qf 2470 15 premaxilla premaxilla NN cord-022526-j9kg00qf 2470 16 across across IN cord-022526-j9kg00qf 2470 17 the the DT cord-022526-j9kg00qf 2470 18 nose nose NN cord-022526-j9kg00qf 2470 19 at at IN cord-022526-j9kg00qf 2470 20 the the DT cord-022526-j9kg00qf 2470 21 line line NN cord-022526-j9kg00qf 2470 22 of of IN cord-022526-j9kg00qf 2470 23 the the DT cord-022526-j9kg00qf 2470 24 first first JJ cord-022526-j9kg00qf 2470 25 cheek cheek NN cord-022526-j9kg00qf 2470 26 tooth tooth NN cord-022526-j9kg00qf 2470 27 . . . cord-022526-j9kg00qf 2471 1 Circumstantial circumstantial JJ cord-022526-j9kg00qf 2471 2 evidence evidence NN cord-022526-j9kg00qf 2471 3 indicates indicate VBZ cord-022526-j9kg00qf 2471 4 that that IN cord-022526-j9kg00qf 2471 5 such such PDT cord-022526-j9kg00qf 2471 6 a a DT cord-022526-j9kg00qf 2471 7 defect defect NN cord-022526-j9kg00qf 2471 8 has have VBZ cord-022526-j9kg00qf 2471 9 a a DT cord-022526-j9kg00qf 2471 10 genetic genetic JJ cord-022526-j9kg00qf 2471 11 cause cause NN cord-022526-j9kg00qf 2471 12 , , , cord-022526-j9kg00qf 2471 13 and and CC cord-022526-j9kg00qf 2471 14 the the DT cord-022526-j9kg00qf 2471 15 defect defect NN cord-022526-j9kg00qf 2471 16 occurs occur VBZ cord-022526-j9kg00qf 2471 17 most most RBS cord-022526-j9kg00qf 2471 18 frequently frequently RB cord-022526-j9kg00qf 2471 19 in in IN cord-022526-j9kg00qf 2471 20 the the DT cord-022526-j9kg00qf 2471 21 Arabian arabian JJ cord-022526-j9kg00qf 2471 22 breed breed NN cord-022526-j9kg00qf 2471 23 . . . cord-022526-j9kg00qf 2472 1 Other other JJ cord-022526-j9kg00qf 2472 2 developmental developmental JJ cord-022526-j9kg00qf 2472 3 abnormalities abnormality NNS cord-022526-j9kg00qf 2472 4 are be VBP cord-022526-j9kg00qf 2472 5 subepiglottic subepiglottic JJ cord-022526-j9kg00qf 2472 6 cysts cyst NNS cord-022526-j9kg00qf 2472 7 resulting result VBG cord-022526-j9kg00qf 2472 8 from from IN cord-022526-j9kg00qf 2472 9 cystic cystic JJ cord-022526-j9kg00qf 2472 10 distortion distortion NN cord-022526-j9kg00qf 2472 11 of of IN cord-022526-j9kg00qf 2472 12 remnants remnant NNS cord-022526-j9kg00qf 2472 13 of of IN cord-022526-j9kg00qf 2472 14 the the DT cord-022526-j9kg00qf 2472 15 thyroglossal thyroglossal NN cord-022526-j9kg00qf 2472 16 duct duct NN cord-022526-j9kg00qf 2472 17 , , , cord-022526-j9kg00qf 2472 18 which which WDT cord-022526-j9kg00qf 2472 19 may may MD cord-022526-j9kg00qf 2472 20 cause cause VB cord-022526-j9kg00qf 2472 21 dyspnea dyspnea NN cord-022526-j9kg00qf 2472 22 and and CC cord-022526-j9kg00qf 2472 23 choking choke VBG cord-022526-j9kg00qf 2472 24 in in IN cord-022526-j9kg00qf 2472 25 foals foal NNS cord-022526-j9kg00qf 2472 26 . . . cord-022526-j9kg00qf 2473 1 Surgical surgical JJ cord-022526-j9kg00qf 2473 2 removal removal NN cord-022526-j9kg00qf 2473 3 of of IN cord-022526-j9kg00qf 2473 4 these these DT cord-022526-j9kg00qf 2473 5 cysts cyst NNS cord-022526-j9kg00qf 2473 6 results result NNS cord-022526-j9kg00qf 2473 7 in in IN cord-022526-j9kg00qf 2473 8 normal normal JJ cord-022526-j9kg00qf 2473 9 function function NN cord-022526-j9kg00qf 2473 10 . . . cord-022526-j9kg00qf 2474 1 The the DT cord-022526-j9kg00qf 2474 2 most most RBS cord-022526-j9kg00qf 2474 3 significant significant JJ cord-022526-j9kg00qf 2474 4 developmental developmental JJ cord-022526-j9kg00qf 2474 5 defect defect NN cord-022526-j9kg00qf 2474 6 of of IN cord-022526-j9kg00qf 2474 7 dental dental JJ cord-022526-j9kg00qf 2474 8 origin origin NN cord-022526-j9kg00qf 2474 9 is be VBZ cord-022526-j9kg00qf 2474 10 a a DT cord-022526-j9kg00qf 2474 11 maxilla maxilla NN cord-022526-j9kg00qf 2474 12 that that WDT cord-022526-j9kg00qf 2474 13 is be VBZ cord-022526-j9kg00qf 2474 14 longer long JJR cord-022526-j9kg00qf 2474 15 than than IN cord-022526-j9kg00qf 2474 16 the the DT cord-022526-j9kg00qf 2474 17 mandible mandible NN cord-022526-j9kg00qf 2474 18 , , , cord-022526-j9kg00qf 2474 19 that that RB cord-022526-j9kg00qf 2474 20 is is RB cord-022526-j9kg00qf 2474 21 , , , cord-022526-j9kg00qf 2474 22 the the DT cord-022526-j9kg00qf 2474 23 horse horse NN cord-022526-j9kg00qf 2474 24 is be VBZ cord-022526-j9kg00qf 2474 25 parrot parrot NN cord-022526-j9kg00qf 2474 26 - - HYPH cord-022526-j9kg00qf 2474 27 mouthed mouthed JJ cord-022526-j9kg00qf 2474 28 . . . cord-022526-j9kg00qf 2475 1 An an DT cord-022526-j9kg00qf 2475 2 overbite overbite NN cord-022526-j9kg00qf 2475 3 of of IN cord-022526-j9kg00qf 2475 4 2 2 CD cord-022526-j9kg00qf 2475 5 cm cm NNS cord-022526-j9kg00qf 2475 6 in in IN cord-022526-j9kg00qf 2475 7 the the DT cord-022526-j9kg00qf 2475 8 incisor incisor NN cord-022526-j9kg00qf 2475 9 arcade arcade NN cord-022526-j9kg00qf 2475 10 may may MD cord-022526-j9kg00qf 2475 11 be be VB cord-022526-j9kg00qf 2475 12 present present JJ cord-022526-j9kg00qf 2475 13 in in IN cord-022526-j9kg00qf 2475 14 a a DT cord-022526-j9kg00qf 2475 15 horse horse NN cord-022526-j9kg00qf 2475 16 with with IN cord-022526-j9kg00qf 2475 17 a a DT cord-022526-j9kg00qf 2475 18 mismatch mismatch NN cord-022526-j9kg00qf 2475 19 of of IN cord-022526-j9kg00qf 2475 20 less less JJR cord-022526-j9kg00qf 2475 21 than than IN cord-022526-j9kg00qf 2475 22 1 1 CD cord-022526-j9kg00qf 2475 23 cm cm NNS cord-022526-j9kg00qf 2475 24 between between IN cord-022526-j9kg00qf 2475 25 the the DT cord-022526-j9kg00qf 2475 26 first first JJ cord-022526-j9kg00qf 2475 27 upper upper JJ cord-022526-j9kg00qf 2475 28 and and CC cord-022526-j9kg00qf 2475 29 lower low JJR cord-022526-j9kg00qf 2475 30 cheek cheek NN cord-022526-j9kg00qf 2475 31 teeth tooth NNS cord-022526-j9kg00qf 2475 32 . . . cord-022526-j9kg00qf 2476 1 Parrot Parrot NNP cord-022526-j9kg00qf 2476 2 mouth mouth NN cord-022526-j9kg00qf 2476 3 and and CC cord-022526-j9kg00qf 2476 4 monkey monkey NN cord-022526-j9kg00qf 2476 5 or or CC cord-022526-j9kg00qf 2476 6 sow sow VB cord-022526-j9kg00qf 2476 7 mouth mouth NN cord-022526-j9kg00qf 2476 8 are be VBP cord-022526-j9kg00qf 2476 9 thought think VBN cord-022526-j9kg00qf 2476 10 to to TO cord-022526-j9kg00qf 2476 11 be be VB cord-022526-j9kg00qf 2476 12 inherited inherit VBN cord-022526-j9kg00qf 2476 13 conditions condition NNS cord-022526-j9kg00qf 2476 14 . . . cord-022526-j9kg00qf 2477 1 Some some DT cord-022526-j9kg00qf 2477 2 correction correction NN cord-022526-j9kg00qf 2477 3 of of IN cord-022526-j9kg00qf 2477 4 minor minor JJ cord-022526-j9kg00qf 2477 5 incisor incisor NN cord-022526-j9kg00qf 2477 6 malocclusion malocclusion NN cord-022526-j9kg00qf 2477 7 occurs occur VBZ cord-022526-j9kg00qf 2477 8 up up IN cord-022526-j9kg00qf 2477 9 to to TO cord-022526-j9kg00qf 2477 10 5 5 CD cord-022526-j9kg00qf 2477 11 years year NNS cord-022526-j9kg00qf 2477 12 of of IN cord-022526-j9kg00qf 2477 13 age age NN cord-022526-j9kg00qf 2477 14 . . . cord-022526-j9kg00qf 2478 1 Recognition recognition NN cord-022526-j9kg00qf 2478 2 and and CC cord-022526-j9kg00qf 2478 3 detection detection NN cord-022526-j9kg00qf 2478 4 of of IN cord-022526-j9kg00qf 2478 5 parrot parrot NN cord-022526-j9kg00qf 2478 6 mouth mouth NN cord-022526-j9kg00qf 2478 7 are be VBP cord-022526-j9kg00qf 2478 8 important important JJ cord-022526-j9kg00qf 2478 9 in in IN cord-022526-j9kg00qf 2478 10 the the DT cord-022526-j9kg00qf 2478 11 examination examination NN cord-022526-j9kg00qf 2478 12 of of IN cord-022526-j9kg00qf 2478 13 potential potential JJ cord-022526-j9kg00qf 2478 14 breeding breeding NN cord-022526-j9kg00qf 2478 15 stock stock NN cord-022526-j9kg00qf 2478 16 . . . cord-022526-j9kg00qf 2479 1 Surgical surgical JJ cord-022526-j9kg00qf 2479 2 attempts attempt NNS cord-022526-j9kg00qf 2479 3 to to TO cord-022526-j9kg00qf 2479 4 inhibit inhibit VB cord-022526-j9kg00qf 2479 5 overgrowth overgrowth NN cord-022526-j9kg00qf 2479 6 of of IN cord-022526-j9kg00qf 2479 7 the the DT cord-022526-j9kg00qf 2479 8 premaxilla premaxilla NN cord-022526-j9kg00qf 2479 9 by by IN cord-022526-j9kg00qf 2479 10 wiring wiring NN cord-022526-j9kg00qf 2479 11 or or CC cord-022526-j9kg00qf 2479 12 by by IN cord-022526-j9kg00qf 2479 13 the the DT cord-022526-j9kg00qf 2479 14 application application NN cord-022526-j9kg00qf 2479 15 of of IN cord-022526-j9kg00qf 2479 16 dental dental JJ cord-022526-j9kg00qf 2479 17 bite bite NN cord-022526-j9kg00qf 2479 18 plate plate NN cord-022526-j9kg00qf 2479 19 procedures procedure NNS cord-022526-j9kg00qf 2479 20 have have VBP cord-022526-j9kg00qf 2479 21 been be VBN cord-022526-j9kg00qf 2479 22 documented document VBN cord-022526-j9kg00qf 2479 23 in in IN cord-022526-j9kg00qf 2479 24 recent recent JJ cord-022526-j9kg00qf 2479 25 years year NNS cord-022526-j9kg00qf 2479 26 . . . cord-022526-j9kg00qf 2480 1 15 15 CD cord-022526-j9kg00qf 2481 1 As as IN cord-022526-j9kg00qf 2481 2 has have VBZ cord-022526-j9kg00qf 2481 3 been be VBN cord-022526-j9kg00qf 2481 4 indicated indicate VBN cord-022526-j9kg00qf 2481 5 , , , cord-022526-j9kg00qf 2481 6 the the DT cord-022526-j9kg00qf 2481 7 horse horse NN cord-022526-j9kg00qf 2481 8 is be VBZ cord-022526-j9kg00qf 2481 9 by by IN cord-022526-j9kg00qf 2481 10 nature nature NN cord-022526-j9kg00qf 2481 11 a a DT cord-022526-j9kg00qf 2481 12 curious curious JJ cord-022526-j9kg00qf 2481 13 animal animal NN cord-022526-j9kg00qf 2481 14 and and CC cord-022526-j9kg00qf 2481 15 uses use VBZ cord-022526-j9kg00qf 2481 16 its -PRON- PRP$ cord-022526-j9kg00qf 2481 17 lips lip NNS cord-022526-j9kg00qf 2481 18 as as IN cord-022526-j9kg00qf 2481 19 a a DT cord-022526-j9kg00qf 2481 20 means means NN cord-022526-j9kg00qf 2481 21 of of IN cord-022526-j9kg00qf 2481 22 exploring explore VBG cord-022526-j9kg00qf 2481 23 a a DT cord-022526-j9kg00qf 2481 24 variety variety NN cord-022526-j9kg00qf 2481 25 of of IN cord-022526-j9kg00qf 2481 26 objects object NNS cord-022526-j9kg00qf 2481 27 . . . cord-022526-j9kg00qf 2482 1 Wounds wound NNS cord-022526-j9kg00qf 2482 2 of of IN cord-022526-j9kg00qf 2482 3 the the DT cord-022526-j9kg00qf 2482 4 lips lip NNS cord-022526-j9kg00qf 2482 5 , , , cord-022526-j9kg00qf 2482 6 incisive incisive JJ cord-022526-j9kg00qf 2482 7 bone bone NN cord-022526-j9kg00qf 2482 8 , , , cord-022526-j9kg00qf 2482 9 and and CC cord-022526-j9kg00qf 2482 10 the the DT cord-022526-j9kg00qf 2482 11 mandibular mandibular JJ cord-022526-j9kg00qf 2482 12 incisor incisor NN cord-022526-j9kg00qf 2482 13 area area NN cord-022526-j9kg00qf 2482 14 occur occur VBP cord-022526-j9kg00qf 2482 15 commonly commonly RB cord-022526-j9kg00qf 2482 16 in in IN cord-022526-j9kg00qf 2482 17 the the DT cord-022526-j9kg00qf 2482 18 horse horse NN cord-022526-j9kg00qf 2482 19 and and CC cord-022526-j9kg00qf 2482 20 usually usually RB cord-022526-j9kg00qf 2482 21 result result VBP cord-022526-j9kg00qf 2482 22 from from IN cord-022526-j9kg00qf 2482 23 the the DT cord-022526-j9kg00qf 2482 24 horse horse NN cord-022526-j9kg00qf 2482 25 getting get VBG cord-022526-j9kg00qf 2482 26 the the DT cord-022526-j9kg00qf 2482 27 lips lip NNS cord-022526-j9kg00qf 2482 28 , , , cord-022526-j9kg00qf 2482 29 jaw jaw NN cord-022526-j9kg00qf 2482 30 , , , cord-022526-j9kg00qf 2482 31 or or CC cord-022526-j9kg00qf 2482 32 teeth tooth NNS cord-022526-j9kg00qf 2482 33 caught catch VBN cord-022526-j9kg00qf 2482 34 in in IN cord-022526-j9kg00qf 2482 35 feeding feed VBG cord-022526-j9kg00qf 2482 36 buckets bucket NNS cord-022526-j9kg00qf 2482 37 , , , cord-022526-j9kg00qf 2482 38 in in IN cord-022526-j9kg00qf 2482 39 fence fence NN cord-022526-j9kg00qf 2482 40 posts post NNS cord-022526-j9kg00qf 2482 41 , , , cord-022526-j9kg00qf 2482 42 or or CC cord-022526-j9kg00qf 2482 43 in in IN cord-022526-j9kg00qf 2482 44 halters halter NNS cord-022526-j9kg00qf 2482 45 or or CC cord-022526-j9kg00qf 2482 46 having have VBG cord-022526-j9kg00qf 2482 47 a a DT cord-022526-j9kg00qf 2482 48 segment segment NN cord-022526-j9kg00qf 2482 49 of of IN cord-022526-j9kg00qf 2482 50 tongue tongue NN cord-022526-j9kg00qf 2482 51 encircled encircle VBN cord-022526-j9kg00qf 2482 52 with with IN cord-022526-j9kg00qf 2482 53 hair hair NN cord-022526-j9kg00qf 2482 54 in in IN cord-022526-j9kg00qf 2482 55 tail tail NN cord-022526-j9kg00qf 2482 56 chewing chewing NN cord-022526-j9kg00qf 2482 57 . . . cord-022526-j9kg00qf 2483 1 As as IN cord-022526-j9kg00qf 2483 2 the the DT cord-022526-j9kg00qf 2483 3 horse horse NN cord-022526-j9kg00qf 2483 4 panics panic VBZ cord-022526-j9kg00qf 2483 5 and and CC cord-022526-j9kg00qf 2483 6 pulls pull VBZ cord-022526-j9kg00qf 2483 7 away away RB cord-022526-j9kg00qf 2483 8 from from IN cord-022526-j9kg00qf 2483 9 its -PRON- PRP$ cord-022526-j9kg00qf 2483 10 oral oral JJ cord-022526-j9kg00qf 2483 11 entrapment entrapment NN cord-022526-j9kg00qf 2483 12 , , , cord-022526-j9kg00qf 2483 13 considerable considerable JJ cord-022526-j9kg00qf 2483 14 trauma trauma NN cord-022526-j9kg00qf 2483 15 can can MD cord-022526-j9kg00qf 2483 16 occur occur VB cord-022526-j9kg00qf 2483 17 to to IN cord-022526-j9kg00qf 2483 18 the the DT cord-022526-j9kg00qf 2483 19 lips lip NNS cord-022526-j9kg00qf 2483 20 , , , cord-022526-j9kg00qf 2483 21 teeth tooth NNS cord-022526-j9kg00qf 2483 22 , , , cord-022526-j9kg00qf 2483 23 and and CC cord-022526-j9kg00qf 2483 24 gums gum NNS cord-022526-j9kg00qf 2483 25 . . . cord-022526-j9kg00qf 2484 1 Most Most JJS cord-022526-j9kg00qf 2484 2 wounds wound NNS cord-022526-j9kg00qf 2484 3 repair repair VBP cord-022526-j9kg00qf 2484 4 satisfactorily satisfactorily RB cord-022526-j9kg00qf 2484 5 , , , cord-022526-j9kg00qf 2484 6 provided provide VBD cord-022526-j9kg00qf 2484 7 one one PRP cord-022526-j9kg00qf 2484 8 finds find VBZ cord-022526-j9kg00qf 2484 9 them -PRON- PRP cord-022526-j9kg00qf 2484 10 early early RB cord-022526-j9kg00qf 2484 11 and and CC cord-022526-j9kg00qf 2484 12 observes observe VBZ cord-022526-j9kg00qf 2484 13 the the DT cord-022526-j9kg00qf 2484 14 basic basic JJ cord-022526-j9kg00qf 2484 15 principles principle NNS cord-022526-j9kg00qf 2484 16 of of IN cord-022526-j9kg00qf 2484 17 wound wound NN cord-022526-j9kg00qf 2484 18 hygiene hygiene NN cord-022526-j9kg00qf 2484 19 , , , cord-022526-j9kg00qf 2484 20 excision excision NN cord-022526-j9kg00qf 2484 21 of of IN cord-022526-j9kg00qf 2484 22 necrotic necrotic JJ cord-022526-j9kg00qf 2484 23 tissue tissue NN cord-022526-j9kg00qf 2484 24 , , , cord-022526-j9kg00qf 2484 25 and and CC cord-022526-j9kg00qf 2484 26 wound wound NN cord-022526-j9kg00qf 2484 27 closure closure NN cord-022526-j9kg00qf 2484 28 . . . cord-022526-j9kg00qf 2485 1 One one PRP cord-022526-j9kg00qf 2485 2 must must MD cord-022526-j9kg00qf 2485 3 ensure ensure VB cord-022526-j9kg00qf 2485 4 that that IN cord-022526-j9kg00qf 2485 5 oral oral JJ cord-022526-j9kg00qf 2485 6 mucosal mucosal JJ cord-022526-j9kg00qf 2485 7 defects defect NNS cord-022526-j9kg00qf 2485 8 are be VBP cord-022526-j9kg00qf 2485 9 closed close VBN cord-022526-j9kg00qf 2485 10 and and CC cord-022526-j9kg00qf 2485 11 that that IN cord-022526-j9kg00qf 2485 12 effective effective JJ cord-022526-j9kg00qf 2485 13 oral oral JJ cord-022526-j9kg00qf 2485 14 seals seal NNS cord-022526-j9kg00qf 2485 15 are be VBP cord-022526-j9kg00qf 2485 16 made make VBN cord-022526-j9kg00qf 2485 17 before before IN cord-022526-j9kg00qf 2485 18 external external JJ cord-022526-j9kg00qf 2485 19 wounds wound NNS cord-022526-j9kg00qf 2485 20 are be VBP cord-022526-j9kg00qf 2485 21 closed close VBN cord-022526-j9kg00qf 2485 22 . . . cord-022526-j9kg00qf 2486 1 In in IN cord-022526-j9kg00qf 2486 2 some some DT cord-022526-j9kg00qf 2486 3 cases case NNS cord-022526-j9kg00qf 2486 4 , , , cord-022526-j9kg00qf 2486 5 offering offer VBG cord-022526-j9kg00qf 2486 6 specially specially RB cord-022526-j9kg00qf 2486 7 constructed construct VBN cord-022526-j9kg00qf 2486 8 diets diet NNS cord-022526-j9kg00qf 2486 9 or or CC cord-022526-j9kg00qf 2486 10 even even RB cord-022526-j9kg00qf 2486 11 feeding feed VBG cord-022526-j9kg00qf 2486 12 the the DT cord-022526-j9kg00qf 2486 13 horse horse NN cord-022526-j9kg00qf 2486 14 by by IN cord-022526-j9kg00qf 2486 15 nasogastric nasogastric NN cord-022526-j9kg00qf 2486 16 tube tube NN cord-022526-j9kg00qf 2486 17 or or CC cord-022526-j9kg00qf 2486 18 esophagostomy esophagostomy NN cord-022526-j9kg00qf 2486 19 during during IN cord-022526-j9kg00qf 2486 20 the the DT cord-022526-j9kg00qf 2486 21 healing healing NN cord-022526-j9kg00qf 2486 22 processes process NNS cord-022526-j9kg00qf 2486 23 may may MD cord-022526-j9kg00qf 2486 24 be be VB cord-022526-j9kg00qf 2486 25 necessary necessary JJ cord-022526-j9kg00qf 2486 26 . . . cord-022526-j9kg00qf 2487 1 Foreign foreign JJ cord-022526-j9kg00qf 2487 2 body body NN cord-022526-j9kg00qf 2487 3 penetration penetration NN cord-022526-j9kg00qf 2487 4 of of IN cord-022526-j9kg00qf 2487 5 the the DT cord-022526-j9kg00qf 2487 6 tongue tongue NN cord-022526-j9kg00qf 2487 7 , , , cord-022526-j9kg00qf 2487 8 cheek cheek NN cord-022526-j9kg00qf 2487 9 , , , cord-022526-j9kg00qf 2487 10 or or CC cord-022526-j9kg00qf 2487 11 palate palate NN cord-022526-j9kg00qf 2487 12 has have VBZ cord-022526-j9kg00qf 2487 13 been be VBN cord-022526-j9kg00qf 2487 14 reported report VBN cord-022526-j9kg00qf 2487 15 in in IN cord-022526-j9kg00qf 2487 16 grazing graze VBG cord-022526-j9kg00qf 2487 17 and and CC cord-022526-j9kg00qf 2487 18 browsing browse VBG cord-022526-j9kg00qf 2487 19 horses horse NNS cord-022526-j9kg00qf 2487 20 and and CC cord-022526-j9kg00qf 2487 21 in in IN cord-022526-j9kg00qf 2487 22 particular particular JJ cord-022526-j9kg00qf 2487 23 in in IN cord-022526-j9kg00qf 2487 24 horses horse NNS cord-022526-j9kg00qf 2487 25 that that WDT cord-022526-j9kg00qf 2487 26 have have VBP cord-022526-j9kg00qf 2487 27 certain certain JJ cord-022526-j9kg00qf 2487 28 hay hay NN cord-022526-j9kg00qf 2487 29 sources source NNS cord-022526-j9kg00qf 2487 30 that that WDT cord-022526-j9kg00qf 2487 31 contain contain VBP cord-022526-j9kg00qf 2487 32 desiccated desiccated JJ cord-022526-j9kg00qf 2487 33 barley barley NN cord-022526-j9kg00qf 2487 34 awns awn NNS cord-022526-j9kg00qf 2487 35 or or CC cord-022526-j9kg00qf 2487 36 yellow yellow JJ cord-022526-j9kg00qf 2487 37 bristle bristle NN cord-022526-j9kg00qf 2487 38 grass grass NN cord-022526-j9kg00qf 2487 39 . . . cord-022526-j9kg00qf 2488 1 16 16 CD cord-022526-j9kg00qf 2489 1 Other other JJ cord-022526-j9kg00qf 2489 2 plant plant NN cord-022526-j9kg00qf 2489 3 material material NN cord-022526-j9kg00qf 2489 4 and and CC cord-022526-j9kg00qf 2489 5 grass grass NN cord-022526-j9kg00qf 2489 6 awns awn NNS cord-022526-j9kg00qf 2489 7 also also RB cord-022526-j9kg00qf 2489 8 occasionally occasionally RB cord-022526-j9kg00qf 2489 9 may may MD cord-022526-j9kg00qf 2489 10 penetrate penetrate VB cord-022526-j9kg00qf 2489 11 the the DT cord-022526-j9kg00qf 2489 12 tongue tongue NN cord-022526-j9kg00qf 2489 13 , , , cord-022526-j9kg00qf 2489 14 gingiva gingiva NN cord-022526-j9kg00qf 2489 15 , , , cord-022526-j9kg00qf 2489 16 or or CC cord-022526-j9kg00qf 2489 17 cheek cheek NN cord-022526-j9kg00qf 2489 18 , , , cord-022526-j9kg00qf 2489 19 causing cause VBG cord-022526-j9kg00qf 2489 20 inflammation inflammation NN cord-022526-j9kg00qf 2489 21 or or CC cord-022526-j9kg00qf 2489 22 abscesses abscess NNS cord-022526-j9kg00qf 2489 23 . . . cord-022526-j9kg00qf 2490 1 Ulcerative ulcerative JJ cord-022526-j9kg00qf 2490 2 stomatitis stomatitis NN cord-022526-j9kg00qf 2490 3 also also RB cord-022526-j9kg00qf 2490 4 results result VBZ cord-022526-j9kg00qf 2490 5 from from IN cord-022526-j9kg00qf 2490 6 the the DT cord-022526-j9kg00qf 2490 7 toxicity toxicity NN cord-022526-j9kg00qf 2490 8 of of IN cord-022526-j9kg00qf 2490 9 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 2490 10 therapy therapy NN cord-022526-j9kg00qf 2490 11 . . . cord-022526-j9kg00qf 2491 1 17 17 CD cord-022526-j9kg00qf 2491 2 Vesicular Vesicular NNP cord-022526-j9kg00qf 2491 3 stomatitis stomatitis NN cord-022526-j9kg00qf 2491 4 is be VBZ cord-022526-j9kg00qf 2491 5 a a DT cord-022526-j9kg00qf 2491 6 highly highly RB cord-022526-j9kg00qf 2491 7 contagious contagious JJ cord-022526-j9kg00qf 2491 8 viral viral JJ cord-022526-j9kg00qf 2491 9 blistering blistering JJ cord-022526-j9kg00qf 2491 10 disease disease NN cord-022526-j9kg00qf 2491 11 described describe VBN cord-022526-j9kg00qf 2491 12 in in IN cord-022526-j9kg00qf 2491 13 more more JJR cord-022526-j9kg00qf 2491 14 detail detail NN cord-022526-j9kg00qf 2491 15 elsewhere elsewhere RB cord-022526-j9kg00qf 2491 16 . . . cord-022526-j9kg00qf 2492 1 Treatment treatment NN cord-022526-j9kg00qf 2492 2 of of IN cord-022526-j9kg00qf 2492 3 glossitis glossitis NNP cord-022526-j9kg00qf 2492 4 and and CC cord-022526-j9kg00qf 2492 5 stomatitis stomatitis NN cord-022526-j9kg00qf 2492 6 primarily primarily RB cord-022526-j9kg00qf 2492 7 aims aim VBZ cord-022526-j9kg00qf 2492 8 at at IN cord-022526-j9kg00qf 2492 9 removing remove VBG cord-022526-j9kg00qf 2492 10 the the DT cord-022526-j9kg00qf 2492 11 inciting incite VBG cord-022526-j9kg00qf 2492 12 cause cause NN cord-022526-j9kg00qf 2492 13 . . . cord-022526-j9kg00qf 2493 1 Actinobacillus Actinobacillus NNP cord-022526-j9kg00qf 2493 2 lignieresii lignieresii NNP cord-022526-j9kg00qf 2493 3 , , , cord-022526-j9kg00qf 2493 4 the the DT cord-022526-j9kg00qf 2493 5 causative causative JJ cord-022526-j9kg00qf 2493 6 agent agent NN cord-022526-j9kg00qf 2493 7 of of IN cord-022526-j9kg00qf 2493 8 actinobacillosis actinobacillosis NNP cord-022526-j9kg00qf 2493 9 , , , cord-022526-j9kg00qf 2493 10 has have VBZ cord-022526-j9kg00qf 2493 11 been be VBN cord-022526-j9kg00qf 2493 12 isolated isolate VBN cord-022526-j9kg00qf 2493 13 and and CC cord-022526-j9kg00qf 2493 14 identified identify VBN cord-022526-j9kg00qf 2493 15 from from IN cord-022526-j9kg00qf 2493 16 ulcers ulcer NNS cord-022526-j9kg00qf 2493 17 on on IN cord-022526-j9kg00qf 2493 18 the the DT cord-022526-j9kg00qf 2493 19 free free JJ cord-022526-j9kg00qf 2493 20 border border NN cord-022526-j9kg00qf 2493 21 of of IN cord-022526-j9kg00qf 2493 22 the the DT cord-022526-j9kg00qf 2493 23 soft soft JJ cord-022526-j9kg00qf 2493 24 palate palate NN cord-022526-j9kg00qf 2493 25 and and CC cord-022526-j9kg00qf 2493 26 oral oral JJ cord-022526-j9kg00qf 2493 27 and and CC cord-022526-j9kg00qf 2493 28 laryngeal laryngeal JJ cord-022526-j9kg00qf 2493 29 granulomata granulomata NNP cord-022526-j9kg00qf 2493 30 . . . cord-022526-j9kg00qf 2494 1 The the DT cord-022526-j9kg00qf 2494 2 bacterium bacterium NN cord-022526-j9kg00qf 2494 3 also also RB cord-022526-j9kg00qf 2494 4 was be VBD cord-022526-j9kg00qf 2494 5 reported report VBN cord-022526-j9kg00qf 2494 6 in in IN cord-022526-j9kg00qf 2494 7 a a DT cord-022526-j9kg00qf 2494 8 sublingual sublingual JJ cord-022526-j9kg00qf 2494 9 caruncle caruncle NN cord-022526-j9kg00qf 2494 10 in in IN cord-022526-j9kg00qf 2494 11 a a DT cord-022526-j9kg00qf 2494 12 horse horse NN cord-022526-j9kg00qf 2494 13 with with IN cord-022526-j9kg00qf 2494 14 a a DT cord-022526-j9kg00qf 2494 15 greatly greatly RB cord-022526-j9kg00qf 2494 16 swollen swollen JJ cord-022526-j9kg00qf 2494 17 tongue tongue NN cord-022526-j9kg00qf 2494 18 . . . cord-022526-j9kg00qf 2495 1 18 18 CD cord-022526-j9kg00qf 2495 2 Therapy therapy NN cord-022526-j9kg00qf 2495 3 with with IN cord-022526-j9kg00qf 2495 4 150 150 CD cord-022526-j9kg00qf 2495 5 ml ml NNS cord-022526-j9kg00qf 2495 6 of of IN cord-022526-j9kg00qf 2495 7 20 20 CD cord-022526-j9kg00qf 2495 8 % % NN cord-022526-j9kg00qf 2495 9 sodium sodium NN cord-022526-j9kg00qf 2495 10 iodide iodide NN cord-022526-j9kg00qf 2495 11 and and CC cord-022526-j9kg00qf 2495 12 5 5 CD cord-022526-j9kg00qf 2495 13 g g NN cord-022526-j9kg00qf 2495 14 of of IN cord-022526-j9kg00qf 2495 15 ampicillin ampicillin NN cord-022526-j9kg00qf 2495 16 every every DT cord-022526-j9kg00qf 2495 17 8 8 CD cord-022526-j9kg00qf 2495 18 to to TO cord-022526-j9kg00qf 2495 19 12 12 CD cord-022526-j9kg00qf 2495 20 hours hour NNS cord-022526-j9kg00qf 2495 21 effected effect VBD cord-022526-j9kg00qf 2495 22 a a DT cord-022526-j9kg00qf 2495 23 clinical clinical JJ cord-022526-j9kg00qf 2495 24 cure cure NN cord-022526-j9kg00qf 2495 25 . . . cord-022526-j9kg00qf 2496 1 Saliva saliva NN cord-022526-j9kg00qf 2496 2 is be VBZ cord-022526-j9kg00qf 2496 3 important important JJ cord-022526-j9kg00qf 2496 4 for for IN cord-022526-j9kg00qf 2496 5 lubricating lubricate VBG cord-022526-j9kg00qf 2496 6 and and CC cord-022526-j9kg00qf 2496 7 softening soften VBG cord-022526-j9kg00qf 2496 8 food food NN cord-022526-j9kg00qf 2496 9 material material NN cord-022526-j9kg00qf 2496 10 . . . cord-022526-j9kg00qf 2497 1 The the DT cord-022526-j9kg00qf 2497 2 horse horse NN cord-022526-j9kg00qf 2497 3 has have VBZ cord-022526-j9kg00qf 2497 4 paired pair VBN cord-022526-j9kg00qf 2497 5 parotid parotid NN cord-022526-j9kg00qf 2497 6 , , , cord-022526-j9kg00qf 2497 7 mandibular mandibular JJ cord-022526-j9kg00qf 2497 8 , , , cord-022526-j9kg00qf 2497 9 and and CC cord-022526-j9kg00qf 2497 10 polystomatic polystomatic JJ cord-022526-j9kg00qf 2497 11 sublingual sublingual JJ cord-022526-j9kg00qf 2497 12 salivary salivary NN cord-022526-j9kg00qf 2497 13 glands gland NNS cord-022526-j9kg00qf 2497 14 . . . cord-022526-j9kg00qf 2498 1 The the DT cord-022526-j9kg00qf 2498 2 parotid parotid JJ cord-022526-j9kg00qf 2498 3 gland gland NN cord-022526-j9kg00qf 2498 4 is be VBZ cord-022526-j9kg00qf 2498 5 the the DT cord-022526-j9kg00qf 2498 6 largest large JJS cord-022526-j9kg00qf 2498 7 of of IN cord-022526-j9kg00qf 2498 8 the the DT cord-022526-j9kg00qf 2498 9 salivary salivary JJ cord-022526-j9kg00qf 2498 10 glands gland NNS cord-022526-j9kg00qf 2498 11 in in IN cord-022526-j9kg00qf 2498 12 the the DT cord-022526-j9kg00qf 2498 13 horse horse NN cord-022526-j9kg00qf 2498 14 and and CC cord-022526-j9kg00qf 2498 15 is be VBZ cord-022526-j9kg00qf 2498 16 situated situate VBN cord-022526-j9kg00qf 2498 17 in in IN cord-022526-j9kg00qf 2498 18 the the DT cord-022526-j9kg00qf 2498 19 space space NN cord-022526-j9kg00qf 2498 20 between between IN cord-022526-j9kg00qf 2498 21 the the DT cord-022526-j9kg00qf 2498 22 ramus ramus NNP cord-022526-j9kg00qf 2498 23 of of IN cord-022526-j9kg00qf 2498 24 the the DT cord-022526-j9kg00qf 2498 25 mandible mandible NN cord-022526-j9kg00qf 2498 26 and and CC cord-022526-j9kg00qf 2498 27 the the DT cord-022526-j9kg00qf 2498 28 wing wing NN cord-022526-j9kg00qf 2498 29 of of IN cord-022526-j9kg00qf 2498 30 the the DT cord-022526-j9kg00qf 2498 31 atlas atlas NNP cord-022526-j9kg00qf 2498 32 . . . cord-022526-j9kg00qf 2499 1 The the DT cord-022526-j9kg00qf 2499 2 parotid parotid JJ cord-022526-j9kg00qf 2499 3 duct duct NN cord-022526-j9kg00qf 2499 4 is be VBZ cord-022526-j9kg00qf 2499 5 formed form VBN cord-022526-j9kg00qf 2499 6 at at IN cord-022526-j9kg00qf 2499 7 the the DT cord-022526-j9kg00qf 2499 8 ventral ventral JJ cord-022526-j9kg00qf 2499 9 part part NN cord-022526-j9kg00qf 2499 10 of of IN cord-022526-j9kg00qf 2499 11 the the DT cord-022526-j9kg00qf 2499 12 gland gland NN cord-022526-j9kg00qf 2499 13 near near IN cord-022526-j9kg00qf 2499 14 the the DT cord-022526-j9kg00qf 2499 15 facial facial JJ cord-022526-j9kg00qf 2499 16 crest crest NN cord-022526-j9kg00qf 2499 17 by by IN cord-022526-j9kg00qf 2499 18 the the DT cord-022526-j9kg00qf 2499 19 union union NN cord-022526-j9kg00qf 2499 20 of of IN cord-022526-j9kg00qf 2499 21 three three CD cord-022526-j9kg00qf 2499 22 or or CC cord-022526-j9kg00qf 2499 23 four four CD cord-022526-j9kg00qf 2499 24 smaller small JJR cord-022526-j9kg00qf 2499 25 ducts duct NNS cord-022526-j9kg00qf 2499 26 . . . cord-022526-j9kg00qf 2500 1 The the DT cord-022526-j9kg00qf 2500 2 duct duct NN cord-022526-j9kg00qf 2500 3 leaves leave VBZ cord-022526-j9kg00qf 2500 4 the the DT cord-022526-j9kg00qf 2500 5 gland gland NN cord-022526-j9kg00qf 2500 6 above above IN cord-022526-j9kg00qf 2500 7 the the DT cord-022526-j9kg00qf 2500 8 linguofacial linguofacial JJ cord-022526-j9kg00qf 2500 9 vein vein NN cord-022526-j9kg00qf 2500 10 , , , cord-022526-j9kg00qf 2500 11 crosses cross VBZ cord-022526-j9kg00qf 2500 12 the the DT cord-022526-j9kg00qf 2500 13 tendon tendon NN cord-022526-j9kg00qf 2500 14 of of IN cord-022526-j9kg00qf 2500 15 the the DT cord-022526-j9kg00qf 2500 16 sternocephalicus sternocephalicus NN cord-022526-j9kg00qf 2500 17 muscle muscle NN cord-022526-j9kg00qf 2500 18 , , , cord-022526-j9kg00qf 2500 19 and and CC cord-022526-j9kg00qf 2500 20 enters enter VBZ cord-022526-j9kg00qf 2500 21 the the DT cord-022526-j9kg00qf 2500 22 mouth mouth NN cord-022526-j9kg00qf 2500 23 obliquely obliquely RB cord-022526-j9kg00qf 2500 24 in in IN cord-022526-j9kg00qf 2500 25 the the DT cord-022526-j9kg00qf 2500 26 cheek cheek NN cord-022526-j9kg00qf 2500 27 opposite opposite IN cord-022526-j9kg00qf 2500 28 the the DT cord-022526-j9kg00qf 2500 29 third third JJ cord-022526-j9kg00qf 2500 30 upper upper JJ cord-022526-j9kg00qf 2500 31 cheek cheek NN cord-022526-j9kg00qf 2500 32 tooth tooth NN cord-022526-j9kg00qf 2500 33 . . . cord-022526-j9kg00qf 2501 1 The the DT cord-022526-j9kg00qf 2501 2 parotic parotic JJ cord-022526-j9kg00qf 2501 3 duct duct NN cord-022526-j9kg00qf 2501 4 orifice orifice NN cord-022526-j9kg00qf 2501 5 is be VBZ cord-022526-j9kg00qf 2501 6 small small JJ cord-022526-j9kg00qf 2501 7 , , , cord-022526-j9kg00qf 2501 8 but but CC cord-022526-j9kg00qf 2501 9 some some DT cord-022526-j9kg00qf 2501 10 dilation dilation NN cord-022526-j9kg00qf 2501 11 of of IN cord-022526-j9kg00qf 2501 12 the the DT cord-022526-j9kg00qf 2501 13 duct duct NN cord-022526-j9kg00qf 2501 14 and and CC cord-022526-j9kg00qf 2501 15 a a DT cord-022526-j9kg00qf 2501 16 circular circular JJ cord-022526-j9kg00qf 2501 17 mucous mucous NN cord-022526-j9kg00qf 2501 18 fold fold NN cord-022526-j9kg00qf 2501 19 ( ( -LRB- cord-022526-j9kg00qf 2501 20 the the DT cord-022526-j9kg00qf 2501 21 parotid parotid JJ cord-022526-j9kg00qf 2501 22 papillae papilla NNS cord-022526-j9kg00qf 2501 23 ) ) -RRB- cord-022526-j9kg00qf 2501 24 exist exist VBP cord-022526-j9kg00qf 2501 25 at at IN cord-022526-j9kg00qf 2501 26 this this DT cord-022526-j9kg00qf 2501 27 point point NN cord-022526-j9kg00qf 2501 28 . . . cord-022526-j9kg00qf 2502 1 The the DT cord-022526-j9kg00qf 2502 2 mandibular mandibular JJ cord-022526-j9kg00qf 2502 3 gland gland NN cord-022526-j9kg00qf 2502 4 is be VBZ cord-022526-j9kg00qf 2502 5 smaller small JJR cord-022526-j9kg00qf 2502 6 than than IN cord-022526-j9kg00qf 2502 7 the the DT cord-022526-j9kg00qf 2502 8 parotid parotid JJ cord-022526-j9kg00qf 2502 9 gland gland NN cord-022526-j9kg00qf 2502 10 and and CC cord-022526-j9kg00qf 2502 11 extends extend VBZ cord-022526-j9kg00qf 2502 12 from from IN cord-022526-j9kg00qf 2502 13 the the DT cord-022526-j9kg00qf 2502 14 atlantal atlantal JJ cord-022526-j9kg00qf 2502 15 fossa fossa NN cord-022526-j9kg00qf 2502 16 to to IN cord-022526-j9kg00qf 2502 17 the the DT cord-022526-j9kg00qf 2502 18 basihyoid basihyoid JJ cord-022526-j9kg00qf 2502 19 bone bone NN cord-022526-j9kg00qf 2502 20 . . . cord-022526-j9kg00qf 2503 1 For for IN cord-022526-j9kg00qf 2503 2 the the DT cord-022526-j9kg00qf 2503 3 most most JJS cord-022526-j9kg00qf 2503 4 part part NN cord-022526-j9kg00qf 2503 5 , , , cord-022526-j9kg00qf 2503 6 the the DT cord-022526-j9kg00qf 2503 7 mandibular mandibular JJ cord-022526-j9kg00qf 2503 8 gland gland NN cord-022526-j9kg00qf 2503 9 is be VBZ cord-022526-j9kg00qf 2503 10 covered cover VBN cord-022526-j9kg00qf 2503 11 by by IN cord-022526-j9kg00qf 2503 12 the the DT cord-022526-j9kg00qf 2503 13 parotid parotid JJ cord-022526-j9kg00qf 2503 14 gland gland NN cord-022526-j9kg00qf 2503 15 and and CC cord-022526-j9kg00qf 2503 16 by by IN cord-022526-j9kg00qf 2503 17 the the DT cord-022526-j9kg00qf 2503 18 lower low JJR cord-022526-j9kg00qf 2503 19 jaw jaw NN cord-022526-j9kg00qf 2503 20 . . . cord-022526-j9kg00qf 2504 1 The the DT cord-022526-j9kg00qf 2504 2 mandibular mandibular JJ cord-022526-j9kg00qf 2504 3 duct duct NN cord-022526-j9kg00qf 2504 4 is be VBZ cord-022526-j9kg00qf 2504 5 formed form VBN cord-022526-j9kg00qf 2504 6 by by IN cord-022526-j9kg00qf 2504 7 union union NN cord-022526-j9kg00qf 2504 8 of of IN cord-022526-j9kg00qf 2504 9 a a DT cord-022526-j9kg00qf 2504 10 number number NN cord-022526-j9kg00qf 2504 11 of of IN cord-022526-j9kg00qf 2504 12 small small JJ cord-022526-j9kg00qf 2504 13 duct duct NN cord-022526-j9kg00qf 2504 14 radicles radicle NNS cord-022526-j9kg00qf 2504 15 that that WDT cord-022526-j9kg00qf 2504 16 emerge emerge VBP cord-022526-j9kg00qf 2504 17 along along IN cord-022526-j9kg00qf 2504 18 the the DT cord-022526-j9kg00qf 2504 19 concave concave JJ cord-022526-j9kg00qf 2504 20 edge edge NN cord-022526-j9kg00qf 2504 21 of of IN cord-022526-j9kg00qf 2504 22 the the DT cord-022526-j9kg00qf 2504 23 gland gland NN cord-022526-j9kg00qf 2504 24 and and CC cord-022526-j9kg00qf 2504 25 run run VB cord-022526-j9kg00qf 2504 26 rostral rostral RB cord-022526-j9kg00qf 2504 27 to to IN cord-022526-j9kg00qf 2504 28 the the DT cord-022526-j9kg00qf 2504 29 border border NN cord-022526-j9kg00qf 2504 30 of of IN cord-022526-j9kg00qf 2504 31 the the DT cord-022526-j9kg00qf 2504 32 mouth mouth NN cord-022526-j9kg00qf 2504 33 opposite opposite IN cord-022526-j9kg00qf 2504 34 the the DT cord-022526-j9kg00qf 2504 35 canine canine JJ cord-022526-j9kg00qf 2504 36 tooth tooth NN cord-022526-j9kg00qf 2504 37 . . . cord-022526-j9kg00qf 2505 1 The the DT cord-022526-j9kg00qf 2505 2 orifice orifice NN cord-022526-j9kg00qf 2505 3 is be VBZ cord-022526-j9kg00qf 2505 4 at at IN cord-022526-j9kg00qf 2505 5 the the DT cord-022526-j9kg00qf 2505 6 end end NN cord-022526-j9kg00qf 2505 7 of of IN cord-022526-j9kg00qf 2505 8 a a DT cord-022526-j9kg00qf 2505 9 sublingual sublingual JJ cord-022526-j9kg00qf 2505 10 caruncle caruncle NN cord-022526-j9kg00qf 2505 11 . . . cord-022526-j9kg00qf 2506 1 The the DT cord-022526-j9kg00qf 2506 2 mandibular mandibular JJ cord-022526-j9kg00qf 2506 3 gland gland NN cord-022526-j9kg00qf 2506 4 possesses possess VBZ cord-022526-j9kg00qf 2506 5 serous serous JJ cord-022526-j9kg00qf 2506 6 , , , cord-022526-j9kg00qf 2506 7 mucous mucous JJ cord-022526-j9kg00qf 2506 8 , , , cord-022526-j9kg00qf 2506 9 and and CC cord-022526-j9kg00qf 2506 10 mixed mixed JJ cord-022526-j9kg00qf 2506 11 alveolar alveolar NN cord-022526-j9kg00qf 2506 12 glandular glandular JJ cord-022526-j9kg00qf 2506 13 components component NNS cord-022526-j9kg00qf 2506 14 . . . cord-022526-j9kg00qf 2507 1 The the DT cord-022526-j9kg00qf 2507 2 parotid parotid JJ cord-022526-j9kg00qf 2507 3 gland gland NN cord-022526-j9kg00qf 2507 4 is be VBZ cord-022526-j9kg00qf 2507 5 a a DT cord-022526-j9kg00qf 2507 6 compound compound NN cord-022526-j9kg00qf 2507 7 alveolar alveolar NN cord-022526-j9kg00qf 2507 8 serous serous JJ cord-022526-j9kg00qf 2507 9 gland gland NN cord-022526-j9kg00qf 2507 10 . . . cord-022526-j9kg00qf 2508 1 The the DT cord-022526-j9kg00qf 2508 2 parotid parotid JJ cord-022526-j9kg00qf 2508 3 salivary salivary NN cord-022526-j9kg00qf 2508 4 gland gland NN cord-022526-j9kg00qf 2508 5 can can MD cord-022526-j9kg00qf 2508 6 secrete secrete VB cord-022526-j9kg00qf 2508 7 saliva saliva NN cord-022526-j9kg00qf 2508 8 to to TO cord-022526-j9kg00qf 2508 9 yield yield VB cord-022526-j9kg00qf 2508 10 rates rate NNS cord-022526-j9kg00qf 2508 11 of of IN cord-022526-j9kg00qf 2508 12 50 50 CD cord-022526-j9kg00qf 2508 13 ml ml NNS cord-022526-j9kg00qf 2508 14 / / SYM cord-022526-j9kg00qf 2508 15 min min NN cord-022526-j9kg00qf 2508 16 , , , cord-022526-j9kg00qf 2508 17 and and CC cord-022526-j9kg00qf 2508 18 a a DT cord-022526-j9kg00qf 2508 19 total total JJ cord-022526-j9kg00qf 2508 20 daily daily JJ cord-022526-j9kg00qf 2508 21 parotid parotid JJ cord-022526-j9kg00qf 2508 22 secretion secretion NN cord-022526-j9kg00qf 2508 23 can can MD cord-022526-j9kg00qf 2508 24 be be VB cord-022526-j9kg00qf 2508 25 as as RB cord-022526-j9kg00qf 2508 26 much much JJ cord-022526-j9kg00qf 2508 27 as as IN cord-022526-j9kg00qf 2508 28 12 12 CD cord-022526-j9kg00qf 2508 29 L l NN cord-022526-j9kg00qf 2508 30 in in IN cord-022526-j9kg00qf 2508 31 a a DT cord-022526-j9kg00qf 2508 32 500-kg 500-kg CD cord-022526-j9kg00qf 2508 33 horse horse NN cord-022526-j9kg00qf 2508 34 . . . cord-022526-j9kg00qf 2509 1 Parotid parotid JJ cord-022526-j9kg00qf 2509 2 secretion secretion NN cord-022526-j9kg00qf 2509 3 only only RB cord-022526-j9kg00qf 2509 4 occurs occur VBZ cord-022526-j9kg00qf 2509 5 during during IN cord-022526-j9kg00qf 2509 6 mastication mastication NN cord-022526-j9kg00qf 2509 7 , , , cord-022526-j9kg00qf 2509 8 and and CC cord-022526-j9kg00qf 2509 9 administration administration NN cord-022526-j9kg00qf 2509 10 of of IN cord-022526-j9kg00qf 2509 11 atropine atropine NN cord-022526-j9kg00qf 2509 12 or or CC cord-022526-j9kg00qf 2509 13 anesthesia anesthesia NN cord-022526-j9kg00qf 2509 14 of of IN cord-022526-j9kg00qf 2509 15 the the DT cord-022526-j9kg00qf 2509 16 oral oral JJ cord-022526-j9kg00qf 2509 17 mucosa mucosa NN cord-022526-j9kg00qf 2509 18 can can MD cord-022526-j9kg00qf 2509 19 block block VB cord-022526-j9kg00qf 2509 20 secretion secretion NN cord-022526-j9kg00qf 2509 21 . . . cord-022526-j9kg00qf 2510 1 Parotid parotid JJ cord-022526-j9kg00qf 2510 2 saliva saliva NN cord-022526-j9kg00qf 2510 3 is be VBZ cord-022526-j9kg00qf 2510 4 hypotonic hypotonic JJ cord-022526-j9kg00qf 2510 5 compared compare VBN cord-022526-j9kg00qf 2510 6 with with IN cord-022526-j9kg00qf 2510 7 plasma plasma NN cord-022526-j9kg00qf 2510 8 , , , cord-022526-j9kg00qf 2510 9 but but CC cord-022526-j9kg00qf 2510 10 at at IN cord-022526-j9kg00qf 2510 11 high high JJ cord-022526-j9kg00qf 2510 12 rates rate NNS cord-022526-j9kg00qf 2510 13 of of IN cord-022526-j9kg00qf 2510 14 flow flow NN cord-022526-j9kg00qf 2510 15 , , , cord-022526-j9kg00qf 2510 16 concentrations concentration NNS cord-022526-j9kg00qf 2510 17 of of IN cord-022526-j9kg00qf 2510 18 sodium sodium NN cord-022526-j9kg00qf 2510 19 , , , cord-022526-j9kg00qf 2510 20 chloride chloride NN cord-022526-j9kg00qf 2510 21 , , , cord-022526-j9kg00qf 2510 22 and and CC cord-022526-j9kg00qf 2510 23 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2510 24 ions ion NNS cord-022526-j9kg00qf 2510 25 increase increase VBP cord-022526-j9kg00qf 2510 26 . . . cord-022526-j9kg00qf 2511 1 Parotid parotid JJ cord-022526-j9kg00qf 2511 2 saliva saliva NN cord-022526-j9kg00qf 2511 3 of of IN cord-022526-j9kg00qf 2511 4 the the DT cord-022526-j9kg00qf 2511 5 horse horse NN cord-022526-j9kg00qf 2511 6 has have VBZ cord-022526-j9kg00qf 2511 7 a a DT cord-022526-j9kg00qf 2511 8 high high JJ cord-022526-j9kg00qf 2511 9 concentration concentration NN cord-022526-j9kg00qf 2511 10 of of IN cord-022526-j9kg00qf 2511 11 calcium calcium NN cord-022526-j9kg00qf 2511 12 , , , cord-022526-j9kg00qf 2511 13 and and CC cord-022526-j9kg00qf 2511 14 occasionally occasionally RB cord-022526-j9kg00qf 2511 15 calculi calculus NNS cord-022526-j9kg00qf 2511 16 ( ( -LRB- cord-022526-j9kg00qf 2511 17 sialoliths sialoliths NNP cord-022526-j9kg00qf 2511 18 ) ) -RRB- cord-022526-j9kg00qf 2511 19 form form VBP cord-022526-j9kg00qf 2511 20 within within IN cord-022526-j9kg00qf 2511 21 the the DT cord-022526-j9kg00qf 2511 22 duct duct NN cord-022526-j9kg00qf 2511 23 radicles radicle NNS cord-022526-j9kg00qf 2511 24 of of IN cord-022526-j9kg00qf 2511 25 the the DT cord-022526-j9kg00qf 2511 26 parotid parotid JJ cord-022526-j9kg00qf 2511 27 salivary salivary NN cord-022526-j9kg00qf 2511 28 gland gland NN cord-022526-j9kg00qf 2511 29 . . . cord-022526-j9kg00qf 2512 1 19 19 CD cord-022526-j9kg00qf 2512 2 Congenital congenital JJ cord-022526-j9kg00qf 2512 3 parotid parotid NN cord-022526-j9kg00qf 2512 4 duct duct NN cord-022526-j9kg00qf 2512 5 atresia atresia NN cord-022526-j9kg00qf 2512 6 , , , cord-022526-j9kg00qf 2512 7 acquired acquire VBD cord-022526-j9kg00qf 2512 8 stricture stricture NN cord-022526-j9kg00qf 2512 9 from from IN cord-022526-j9kg00qf 2512 10 trauma trauma NN cord-022526-j9kg00qf 2512 11 to to IN cord-022526-j9kg00qf 2512 12 the the DT cord-022526-j9kg00qf 2512 13 duct duct NN cord-022526-j9kg00qf 2512 14 , , , cord-022526-j9kg00qf 2512 15 or or CC cord-022526-j9kg00qf 2512 16 obstruction obstruction NN cord-022526-j9kg00qf 2512 17 by by IN cord-022526-j9kg00qf 2512 18 plant plant NN cord-022526-j9kg00qf 2512 19 material material NN cord-022526-j9kg00qf 2512 20 ( ( -LRB- cord-022526-j9kg00qf 2512 21 sticks stick NNS cord-022526-j9kg00qf 2512 22 or or CC cord-022526-j9kg00qf 2512 23 foxtails foxtail NNS cord-022526-j9kg00qf 2512 24 and and CC cord-022526-j9kg00qf 2512 25 other other JJ cord-022526-j9kg00qf 2512 26 seeds seed NNS cord-022526-j9kg00qf 2512 27 ) ) -RRB- cord-022526-j9kg00qf 2512 28 also also RB cord-022526-j9kg00qf 2512 29 may may MD cord-022526-j9kg00qf 2512 30 occur occur VB cord-022526-j9kg00qf 2512 31 . . . cord-022526-j9kg00qf 2513 1 The the DT cord-022526-j9kg00qf 2513 2 clinical clinical JJ cord-022526-j9kg00qf 2513 3 signs sign NNS cord-022526-j9kg00qf 2513 4 of of IN cord-022526-j9kg00qf 2513 5 sialolithiasis sialolithiasis NNP cord-022526-j9kg00qf 2513 6 or or CC cord-022526-j9kg00qf 2513 7 other other JJ cord-022526-j9kg00qf 2513 8 forms form NNS cord-022526-j9kg00qf 2513 9 of of IN cord-022526-j9kg00qf 2513 10 ductule ductule JJ cord-022526-j9kg00qf 2513 11 obstruction obstruction NN cord-022526-j9kg00qf 2513 12 include include VBP cord-022526-j9kg00qf 2513 13 a a DT cord-022526-j9kg00qf 2513 14 fluid fluid JJ cord-022526-j9kg00qf 2513 15 swelling swelling NN cord-022526-j9kg00qf 2513 16 in in IN cord-022526-j9kg00qf 2513 17 the the DT cord-022526-j9kg00qf 2513 18 form form NN cord-022526-j9kg00qf 2513 19 of of IN cord-022526-j9kg00qf 2513 20 a a DT cord-022526-j9kg00qf 2513 21 mucocele mucocele NN cord-022526-j9kg00qf 2513 22 proximal proximal JJ cord-022526-j9kg00qf 2513 23 to to IN cord-022526-j9kg00qf 2513 24 the the DT cord-022526-j9kg00qf 2513 25 stone stone NN cord-022526-j9kg00qf 2513 26 and and CC cord-022526-j9kg00qf 2513 27 occasionally occasionally RB cord-022526-j9kg00qf 2513 28 inflammation inflammation NN cord-022526-j9kg00qf 2513 29 of of IN cord-022526-j9kg00qf 2513 30 the the DT cord-022526-j9kg00qf 2513 31 parotid parotid JJ cord-022526-j9kg00qf 2513 32 gland gland NN cord-022526-j9kg00qf 2513 33 . . . cord-022526-j9kg00qf 2514 1 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 2514 2 is be VBZ cord-022526-j9kg00qf 2514 3 useful useful JJ cord-022526-j9kg00qf 2514 4 to to TO cord-022526-j9kg00qf 2514 5 diagnose diagnose VB cord-022526-j9kg00qf 2514 6 salivary salivary JJ cord-022526-j9kg00qf 2514 7 mucoceles mucocele NNS cord-022526-j9kg00qf 2514 8 and and CC cord-022526-j9kg00qf 2514 9 to to TO cord-022526-j9kg00qf 2514 10 detect detect VB cord-022526-j9kg00qf 2514 11 foreign foreign JJ cord-022526-j9kg00qf 2514 12 bodies body NNS cord-022526-j9kg00qf 2514 13 or or CC cord-022526-j9kg00qf 2514 14 sialoliths sialolith NNS cord-022526-j9kg00qf 2514 15 . . . cord-022526-j9kg00qf 2515 1 Measurement measurement NN cord-022526-j9kg00qf 2515 2 of of IN cord-022526-j9kg00qf 2515 3 electrolyte electrolyte JJ cord-022526-j9kg00qf 2515 4 concentrations concentration NNS cord-022526-j9kg00qf 2515 5 in in IN cord-022526-j9kg00qf 2515 6 aspirates aspirate NNS cord-022526-j9kg00qf 2515 7 from from IN cord-022526-j9kg00qf 2515 8 suspected suspect VBN cord-022526-j9kg00qf 2515 9 mucoceles mucocele NNS cord-022526-j9kg00qf 2515 10 might may MD cord-022526-j9kg00qf 2515 11 be be VB cord-022526-j9kg00qf 2515 12 helpful helpful JJ cord-022526-j9kg00qf 2515 13 to to TO cord-022526-j9kg00qf 2515 14 distinguish distinguish VB cord-022526-j9kg00qf 2515 15 them -PRON- PRP cord-022526-j9kg00qf 2515 16 from from IN cord-022526-j9kg00qf 2515 17 hematomas hematoma NNS cord-022526-j9kg00qf 2515 18 . . . cord-022526-j9kg00qf 2516 1 Salivary salivary NN cord-022526-j9kg00qf 2516 2 potassium potassium NN cord-022526-j9kg00qf 2516 3 and and CC cord-022526-j9kg00qf 2516 4 calcium calcium NN cord-022526-j9kg00qf 2516 5 concentrations concentration NNS cord-022526-j9kg00qf 2516 6 are be VBP cord-022526-j9kg00qf 2516 7 higher high JJR cord-022526-j9kg00qf 2516 8 than than IN cord-022526-j9kg00qf 2516 9 plasma plasma NN cord-022526-j9kg00qf 2516 10 . . . cord-022526-j9kg00qf 2517 1 Treatment treatment NN cord-022526-j9kg00qf 2517 2 may may MD cord-022526-j9kg00qf 2517 3 require require VB cord-022526-j9kg00qf 2517 4 surgical surgical JJ cord-022526-j9kg00qf 2517 5 removal removal NN cord-022526-j9kg00qf 2517 6 of of IN cord-022526-j9kg00qf 2517 7 the the DT cord-022526-j9kg00qf 2517 8 stone stone NN cord-022526-j9kg00qf 2517 9 or or CC cord-022526-j9kg00qf 2517 10 plant plant NN cord-022526-j9kg00qf 2517 11 material material NN cord-022526-j9kg00qf 2517 12 in in IN cord-022526-j9kg00qf 2517 13 the the DT cord-022526-j9kg00qf 2517 14 case case NN cord-022526-j9kg00qf 2517 15 of of IN cord-022526-j9kg00qf 2517 16 sialolithiasis sialolithiasis NNP cord-022526-j9kg00qf 2517 17 or or CC cord-022526-j9kg00qf 2517 18 foreign foreign JJ cord-022526-j9kg00qf 2517 19 body body NN cord-022526-j9kg00qf 2517 20 obstructions obstruction NNS cord-022526-j9kg00qf 2517 21 . . . cord-022526-j9kg00qf 2518 1 Other other JJ cord-022526-j9kg00qf 2518 2 causes cause NNS cord-022526-j9kg00qf 2518 3 of of IN cord-022526-j9kg00qf 2518 4 obstruction obstruction NN cord-022526-j9kg00qf 2518 5 may may MD cord-022526-j9kg00qf 2518 6 require require VB cord-022526-j9kg00qf 2518 7 resection resection NN cord-022526-j9kg00qf 2518 8 of of IN cord-022526-j9kg00qf 2518 9 the the DT cord-022526-j9kg00qf 2518 10 affected affected JJ cord-022526-j9kg00qf 2518 11 portion portion NN cord-022526-j9kg00qf 2518 12 of of IN cord-022526-j9kg00qf 2518 13 the the DT cord-022526-j9kg00qf 2518 14 duct duct NN cord-022526-j9kg00qf 2518 15 or or CC cord-022526-j9kg00qf 2518 16 chemical chemical JJ cord-022526-j9kg00qf 2518 17 ablation ablation NN cord-022526-j9kg00qf 2518 18 of of IN cord-022526-j9kg00qf 2518 19 the the DT cord-022526-j9kg00qf 2518 20 gland gland NN cord-022526-j9kg00qf 2518 21 . . . cord-022526-j9kg00qf 2519 1 20 20 CD cord-022526-j9kg00qf 2519 2 Primary primary JJ cord-022526-j9kg00qf 2519 3 sialoadenitis sialoadenitis NN cord-022526-j9kg00qf 2519 4 is be VBZ cord-022526-j9kg00qf 2519 5 unusual unusual JJ cord-022526-j9kg00qf 2519 6 but but CC cord-022526-j9kg00qf 2519 7 can can MD cord-022526-j9kg00qf 2519 8 occur occur VB cord-022526-j9kg00qf 2519 9 in in IN cord-022526-j9kg00qf 2519 10 one one CD cord-022526-j9kg00qf 2519 11 or or CC cord-022526-j9kg00qf 2519 12 both both DT cord-022526-j9kg00qf 2519 13 glands gland NNS cord-022526-j9kg00qf 2519 14 . . . cord-022526-j9kg00qf 2520 1 The the DT cord-022526-j9kg00qf 2520 2 condition condition NN cord-022526-j9kg00qf 2520 3 is be VBZ cord-022526-j9kg00qf 2520 4 painful painful JJ cord-022526-j9kg00qf 2520 5 and and CC cord-022526-j9kg00qf 2520 6 may may MD cord-022526-j9kg00qf 2520 7 be be VB cord-022526-j9kg00qf 2520 8 associated associate VBN cord-022526-j9kg00qf 2520 9 with with IN cord-022526-j9kg00qf 2520 10 a a DT cord-022526-j9kg00qf 2520 11 fever fever NN cord-022526-j9kg00qf 2520 12 and and CC cord-022526-j9kg00qf 2520 13 anorexia anorexia NN cord-022526-j9kg00qf 2520 14 . . . cord-022526-j9kg00qf 2521 1 Secondary secondary JJ cord-022526-j9kg00qf 2521 2 sialoadenitis sialoadenitis NN cord-022526-j9kg00qf 2521 3 is be VBZ cord-022526-j9kg00qf 2521 4 more more RBR cord-022526-j9kg00qf 2521 5 common common JJ cord-022526-j9kg00qf 2521 6 and and CC cord-022526-j9kg00qf 2521 7 usually usually RB cord-022526-j9kg00qf 2521 8 is be VBZ cord-022526-j9kg00qf 2521 9 associated associate VBN cord-022526-j9kg00qf 2521 10 with with IN cord-022526-j9kg00qf 2521 11 trauma trauma NN cord-022526-j9kg00qf 2521 12 . . . cord-022526-j9kg00qf 2522 1 Infectious infectious JJ cord-022526-j9kg00qf 2522 2 sialoadenitis sialoadenitis NN cord-022526-j9kg00qf 2522 3 from from IN cord-022526-j9kg00qf 2522 4 Corynebacterium Corynebacterium NNP cord-022526-j9kg00qf 2522 5 pseudotuberculosis pseudotuberculosis NN cord-022526-j9kg00qf 2522 6 21 21 CD cord-022526-j9kg00qf 2522 7 or or CC cord-022526-j9kg00qf 2522 8 other other JJ cord-022526-j9kg00qf 2522 9 bacterial bacterial JJ cord-022526-j9kg00qf 2522 10 pathogens pathogen NNS cord-022526-j9kg00qf 2522 11 also also RB cord-022526-j9kg00qf 2522 12 may may MD cord-022526-j9kg00qf 2522 13 occur occur VB cord-022526-j9kg00qf 2522 14 . . . cord-022526-j9kg00qf 2523 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 2523 2 is be VBZ cord-022526-j9kg00qf 2523 3 by by IN cord-022526-j9kg00qf 2523 4 physical physical JJ cord-022526-j9kg00qf 2523 5 examination examination NN cord-022526-j9kg00qf 2523 6 and and CC cord-022526-j9kg00qf 2523 7 by by IN cord-022526-j9kg00qf 2523 8 finding find VBG cord-022526-j9kg00qf 2523 9 an an DT cord-022526-j9kg00qf 2523 10 enlarged enlarged JJ cord-022526-j9kg00qf 2523 11 edematous edematous JJ cord-022526-j9kg00qf 2523 12 parotid parotid JJ cord-022526-j9kg00qf 2523 13 gland gland NN cord-022526-j9kg00qf 2523 14 tissue tissue NN cord-022526-j9kg00qf 2523 15 on on IN cord-022526-j9kg00qf 2523 16 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 2523 17 examination examination NN cord-022526-j9kg00qf 2523 18 . . . cord-022526-j9kg00qf 2524 1 Culture culture NN cord-022526-j9kg00qf 2524 2 and and CC cord-022526-j9kg00qf 2524 3 cytologic cytologic JJ cord-022526-j9kg00qf 2524 4 examination examination NN cord-022526-j9kg00qf 2524 5 of of IN cord-022526-j9kg00qf 2524 6 aspirates aspirate NNS cord-022526-j9kg00qf 2524 7 may may MD cord-022526-j9kg00qf 2524 8 be be VB cord-022526-j9kg00qf 2524 9 useful useful JJ cord-022526-j9kg00qf 2524 10 for for IN cord-022526-j9kg00qf 2524 11 diagnostic diagnostic JJ cord-022526-j9kg00qf 2524 12 purposes purpose NNS cord-022526-j9kg00qf 2524 13 . . . cord-022526-j9kg00qf 2525 1 Treatment treatment NN cord-022526-j9kg00qf 2525 2 in in IN cord-022526-j9kg00qf 2525 3 usually usually RB cord-022526-j9kg00qf 2525 4 palliative palliative JJ cord-022526-j9kg00qf 2525 5 , , , cord-022526-j9kg00qf 2525 6 consisting consist VBG cord-022526-j9kg00qf 2525 7 of of IN cord-022526-j9kg00qf 2525 8 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 2525 9 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2525 10 drugs drug NNS cord-022526-j9kg00qf 2525 11 . . . cord-022526-j9kg00qf 2526 1 Appropriate appropriate JJ cord-022526-j9kg00qf 2526 2 antibiotic antibiotic JJ cord-022526-j9kg00qf 2526 3 therapy therapy NN cord-022526-j9kg00qf 2526 4 is be VBZ cord-022526-j9kg00qf 2526 5 indicated indicate VBN cord-022526-j9kg00qf 2526 6 as as IN cord-022526-j9kg00qf 2526 7 directed direct VBN cord-022526-j9kg00qf 2526 8 by by IN cord-022526-j9kg00qf 2526 9 culture culture NN cord-022526-j9kg00qf 2526 10 and and CC cord-022526-j9kg00qf 2526 11 sensitivity sensitivity NN cord-022526-j9kg00qf 2526 12 results result NNS cord-022526-j9kg00qf 2526 13 . . . cord-022526-j9kg00qf 2527 1 Chemical chemical JJ cord-022526-j9kg00qf 2527 2 irritation irritation NN cord-022526-j9kg00qf 2527 3 , , , cord-022526-j9kg00qf 2527 4 glossitis glossitis NNP cord-022526-j9kg00qf 2527 5 , , , cord-022526-j9kg00qf 2527 6 stomatitis stomatitis NN cord-022526-j9kg00qf 2527 7 , , , cord-022526-j9kg00qf 2527 8 or or CC cord-022526-j9kg00qf 2527 9 other other JJ cord-022526-j9kg00qf 2527 10 causes cause NNS cord-022526-j9kg00qf 2527 11 of of IN cord-022526-j9kg00qf 2527 12 prepharyngeal prepharyngeal NN cord-022526-j9kg00qf 2527 13 dysphagia dysphagia NN cord-022526-j9kg00qf 2527 14 cause cause VBP cord-022526-j9kg00qf 2527 15 ptyalism ptyalism NN cord-022526-j9kg00qf 2527 16 or or CC cord-022526-j9kg00qf 2527 17 excessive excessive JJ cord-022526-j9kg00qf 2527 18 salivation salivation NN cord-022526-j9kg00qf 2527 19 in in IN cord-022526-j9kg00qf 2527 20 horses horse NNS cord-022526-j9kg00qf 2527 21 . . . cord-022526-j9kg00qf 2528 1 Specific specific JJ cord-022526-j9kg00qf 2528 2 therapy therapy NN cord-022526-j9kg00qf 2528 3 for for IN cord-022526-j9kg00qf 2528 4 the the DT cord-022526-j9kg00qf 2528 5 ptyalism ptyalism NN cord-022526-j9kg00qf 2528 6 usually usually RB cord-022526-j9kg00qf 2528 7 is be VBZ cord-022526-j9kg00qf 2528 8 not not RB cord-022526-j9kg00qf 2528 9 required require VBN cord-022526-j9kg00qf 2528 10 as as RB cord-022526-j9kg00qf 2528 11 long long RB cord-022526-j9kg00qf 2528 12 as as IN cord-022526-j9kg00qf 2528 13 salivary salivary JJ cord-022526-j9kg00qf 2528 14 losses loss NNS cord-022526-j9kg00qf 2528 15 are be VBP cord-022526-j9kg00qf 2528 16 not not RB cord-022526-j9kg00qf 2528 17 excessive excessive JJ cord-022526-j9kg00qf 2528 18 , , , cord-022526-j9kg00qf 2528 19 resulting result VBG cord-022526-j9kg00qf 2528 20 in in IN cord-022526-j9kg00qf 2528 21 dehydration dehydration NN cord-022526-j9kg00qf 2528 22 and and CC cord-022526-j9kg00qf 2528 23 electrolyte electrolyte JJ cord-022526-j9kg00qf 2528 24 imbalances imbalance NNS cord-022526-j9kg00qf 2528 25 . . . cord-022526-j9kg00qf 2529 1 Ingestion ingestion NN cord-022526-j9kg00qf 2529 2 of of IN cord-022526-j9kg00qf 2529 3 the the DT cord-022526-j9kg00qf 2529 4 fungal fungal JJ cord-022526-j9kg00qf 2529 5 toxin toxin NN cord-022526-j9kg00qf 2529 6 slaframine slaframine NN cord-022526-j9kg00qf 2529 7 also also RB cord-022526-j9kg00qf 2529 8 causes cause VBZ cord-022526-j9kg00qf 2529 9 hypersalivation hypersalivation NN cord-022526-j9kg00qf 2529 10 in in IN cord-022526-j9kg00qf 2529 11 horses horse NNS cord-022526-j9kg00qf 2529 12 . . . cord-022526-j9kg00qf 2530 1 22 22 CD cord-022526-j9kg00qf 2531 1 The the DT cord-022526-j9kg00qf 2531 2 fungus fungus NN cord-022526-j9kg00qf 2531 3 Rhizoctonia Rhizoctonia NNP cord-022526-j9kg00qf 2531 4 leguminicola leguminicola NNP cord-022526-j9kg00qf 2531 5 , , , cord-022526-j9kg00qf 2531 6 which which WDT cord-022526-j9kg00qf 2531 7 produces produce VBZ cord-022526-j9kg00qf 2531 8 slaframine slaframine NN cord-022526-j9kg00qf 2531 9 , , , cord-022526-j9kg00qf 2531 10 causes cause VBZ cord-022526-j9kg00qf 2531 11 black black JJ cord-022526-j9kg00qf 2531 12 patch patch NN cord-022526-j9kg00qf 2531 13 disease disease NN cord-022526-j9kg00qf 2531 14 in in IN cord-022526-j9kg00qf 2531 15 red red JJ cord-022526-j9kg00qf 2531 16 clover clover NN cord-022526-j9kg00qf 2531 17 . . . cord-022526-j9kg00qf 2532 1 Slaframine Slaframine NNP cord-022526-j9kg00qf 2532 2 is be VBZ cord-022526-j9kg00qf 2532 3 a a DT cord-022526-j9kg00qf 2532 4 parasympathomimetic parasympathomimetic JJ cord-022526-j9kg00qf 2532 5 compound compound NN cord-022526-j9kg00qf 2532 6 that that WDT cord-022526-j9kg00qf 2532 7 stimulates stimulate VBZ cord-022526-j9kg00qf 2532 8 exocrine exocrine JJ cord-022526-j9kg00qf 2532 9 secretion secretion NN cord-022526-j9kg00qf 2532 10 in in IN cord-022526-j9kg00qf 2532 11 the the DT cord-022526-j9kg00qf 2532 12 parotid parotid JJ cord-022526-j9kg00qf 2532 13 gland gland NN cord-022526-j9kg00qf 2532 14 . . . cord-022526-j9kg00qf 2533 1 Slaframine slaframine NN cord-022526-j9kg00qf 2533 2 toxicosis toxicosis NN cord-022526-j9kg00qf 2533 3 most most RBS cord-022526-j9kg00qf 2533 4 commonly commonly RB cord-022526-j9kg00qf 2533 5 occurs occur VBZ cord-022526-j9kg00qf 2533 6 in in IN cord-022526-j9kg00qf 2533 7 the the DT cord-022526-j9kg00qf 2533 8 spring spring NN cord-022526-j9kg00qf 2533 9 or or CC cord-022526-j9kg00qf 2533 10 early early JJ cord-022526-j9kg00qf 2533 11 summer summer NN cord-022526-j9kg00qf 2533 12 and and CC cord-022526-j9kg00qf 2533 13 rarely rarely RB cord-022526-j9kg00qf 2533 14 requires require VBZ cord-022526-j9kg00qf 2533 15 treatment treatment NN cord-022526-j9kg00qf 2533 16 other other JJ cord-022526-j9kg00qf 2533 17 than than IN cord-022526-j9kg00qf 2533 18 removal removal NN cord-022526-j9kg00qf 2533 19 from from IN cord-022526-j9kg00qf 2533 20 the the DT cord-022526-j9kg00qf 2533 21 pasture pasture NN cord-022526-j9kg00qf 2533 22 . . . cord-022526-j9kg00qf 2534 1 Mowing mowing NN cord-022526-j9kg00qf 2534 2 removes remove VBZ cord-022526-j9kg00qf 2534 3 the the DT cord-022526-j9kg00qf 2534 4 source source NN cord-022526-j9kg00qf 2534 5 in in IN cord-022526-j9kg00qf 2534 6 most most JJS cord-022526-j9kg00qf 2534 7 cases case NNS cord-022526-j9kg00qf 2534 8 because because IN cord-022526-j9kg00qf 2534 9 regrowth regrowth NN cord-022526-j9kg00qf 2534 10 in in IN cord-022526-j9kg00qf 2534 11 pastures pasture NNS cord-022526-j9kg00qf 2534 12 often often RB cord-022526-j9kg00qf 2534 13 has have VBZ cord-022526-j9kg00qf 2534 14 less less JJR cord-022526-j9kg00qf 2534 15 fungal fungal JJ cord-022526-j9kg00qf 2534 16 contamination contamination NN cord-022526-j9kg00qf 2534 17 . . . cord-022526-j9kg00qf 2535 1 23 23 CD cord-022526-j9kg00qf 2535 2 15 15 CD cord-022526-j9kg00qf 2535 3 . . . cord-022526-j9kg00qf 2536 1 The the DT cord-022526-j9kg00qf 2536 2 esophagus esophagus NN cord-022526-j9kg00qf 2536 3 has have VBZ cord-022526-j9kg00qf 2536 4 no no DT cord-022526-j9kg00qf 2536 5 digestive digestive JJ cord-022526-j9kg00qf 2536 6 or or CC cord-022526-j9kg00qf 2536 7 absorptive absorptive JJ cord-022526-j9kg00qf 2536 8 functions function NNS cord-022526-j9kg00qf 2536 9 and and CC cord-022526-j9kg00qf 2536 10 serves serve VBZ cord-022526-j9kg00qf 2536 11 as as IN cord-022526-j9kg00qf 2536 12 a a DT cord-022526-j9kg00qf 2536 13 conduit conduit NN cord-022526-j9kg00qf 2536 14 to to IN cord-022526-j9kg00qf 2536 15 the the DT cord-022526-j9kg00qf 2536 16 stomach stomach NN cord-022526-j9kg00qf 2536 17 for for IN cord-022526-j9kg00qf 2536 18 food food NN cord-022526-j9kg00qf 2536 19 , , , cord-022526-j9kg00qf 2536 20 water water NN cord-022526-j9kg00qf 2536 21 , , , cord-022526-j9kg00qf 2536 22 and and CC cord-022526-j9kg00qf 2536 23 salivary salivary JJ cord-022526-j9kg00qf 2536 24 secretions secretion NNS cord-022526-j9kg00qf 2536 25 . . . cord-022526-j9kg00qf 2537 1 The the DT cord-022526-j9kg00qf 2537 2 esophageal esophageal JJ cord-022526-j9kg00qf 2537 3 mucosa mucosa NN cord-022526-j9kg00qf 2537 4 is be VBZ cord-022526-j9kg00qf 2537 5 a a DT cord-022526-j9kg00qf 2537 6 keratinized keratinized JJ cord-022526-j9kg00qf 2537 7 stratified stratified JJ cord-022526-j9kg00qf 2537 8 squamous squamous JJ cord-022526-j9kg00qf 2537 9 epithelium epithelium NN cord-022526-j9kg00qf 2537 10 . . . cord-022526-j9kg00qf 2538 1 1 1 LS cord-022526-j9kg00qf 2539 1 The the DT cord-022526-j9kg00qf 2539 2 submucosa submucosa NN cord-022526-j9kg00qf 2539 3 contains contain VBZ cord-022526-j9kg00qf 2539 4 elastic elastic JJ cord-022526-j9kg00qf 2539 5 fibers fiber NNS cord-022526-j9kg00qf 2539 6 that that WDT cord-022526-j9kg00qf 2539 7 contribute contribute VBP cord-022526-j9kg00qf 2539 8 to to IN cord-022526-j9kg00qf 2539 9 the the DT cord-022526-j9kg00qf 2539 10 longitudinal longitudinal JJ cord-022526-j9kg00qf 2539 11 folds fold NNS cord-022526-j9kg00qf 2539 12 of of IN cord-022526-j9kg00qf 2539 13 the the DT cord-022526-j9kg00qf 2539 14 esophagus esophagus NN cord-022526-j9kg00qf 2539 15 and and CC cord-022526-j9kg00qf 2539 16 confer confer VB cord-022526-j9kg00qf 2539 17 elasticity elasticity NN cord-022526-j9kg00qf 2539 18 to to IN cord-022526-j9kg00qf 2539 19 the the DT cord-022526-j9kg00qf 2539 20 esophageal esophageal JJ cord-022526-j9kg00qf 2539 21 wall wall NN cord-022526-j9kg00qf 2539 22 . . . cord-022526-j9kg00qf 2540 1 A a DT cord-022526-j9kg00qf 2540 2 transition transition NN cord-022526-j9kg00qf 2540 3 occurs occur VBZ cord-022526-j9kg00qf 2540 4 in in IN cord-022526-j9kg00qf 2540 5 the the DT cord-022526-j9kg00qf 2540 6 muscle muscle NN cord-022526-j9kg00qf 2540 7 type type NN cord-022526-j9kg00qf 2540 8 composing compose VBG cord-022526-j9kg00qf 2540 9 the the DT cord-022526-j9kg00qf 2540 10 tunica tunica NNP cord-022526-j9kg00qf 2540 11 muscularis muscularis NNP cord-022526-j9kg00qf 2540 12 from from IN cord-022526-j9kg00qf 2540 13 striated striated JJ cord-022526-j9kg00qf 2540 14 skeletal skeletal JJ cord-022526-j9kg00qf 2540 15 muscle muscle NN cord-022526-j9kg00qf 2540 16 in in IN cord-022526-j9kg00qf 2540 17 the the DT cord-022526-j9kg00qf 2540 18 proximal proximal JJ cord-022526-j9kg00qf 2540 19 two two CD cord-022526-j9kg00qf 2540 20 thirds third NNS cord-022526-j9kg00qf 2540 21 of of IN cord-022526-j9kg00qf 2540 22 the the DT cord-022526-j9kg00qf 2540 23 esophagus esophagus NN cord-022526-j9kg00qf 2540 24 to to TO cord-022526-j9kg00qf 2540 25 smooth smooth JJ cord-022526-j9kg00qf 2540 26 muscle muscle NN cord-022526-j9kg00qf 2540 27 in in IN cord-022526-j9kg00qf 2540 28 the the DT cord-022526-j9kg00qf 2540 29 distal distal JJ cord-022526-j9kg00qf 2540 30 third third NN cord-022526-j9kg00qf 2540 31 . . . cord-022526-j9kg00qf 2541 1 In in IN cord-022526-j9kg00qf 2541 2 the the DT cord-022526-j9kg00qf 2541 3 proximal proximal JJ cord-022526-j9kg00qf 2541 4 esophagus esophagus NN cord-022526-j9kg00qf 2541 5 the the DT cord-022526-j9kg00qf 2541 6 skeletal skeletal JJ cord-022526-j9kg00qf 2541 7 muscle muscle NN cord-022526-j9kg00qf 2541 8 layers layer NNS cord-022526-j9kg00qf 2541 9 spiral spiral VBP cord-022526-j9kg00qf 2541 10 across across IN cord-022526-j9kg00qf 2541 11 one one CD cord-022526-j9kg00qf 2541 12 another another DT cord-022526-j9kg00qf 2541 13 at at IN cord-022526-j9kg00qf 2541 14 angles angle NNS cord-022526-j9kg00qf 2541 15 . . . cord-022526-j9kg00qf 2542 1 Within within IN cord-022526-j9kg00qf 2542 2 the the DT cord-022526-j9kg00qf 2542 3 smooth smooth JJ cord-022526-j9kg00qf 2542 4 muscle muscle NN cord-022526-j9kg00qf 2542 5 layers layer NNS cord-022526-j9kg00qf 2542 6 of of IN cord-022526-j9kg00qf 2542 7 the the DT cord-022526-j9kg00qf 2542 8 distal distal JJ cord-022526-j9kg00qf 2542 9 esophagus esophagus NN cord-022526-j9kg00qf 2542 10 the the DT cord-022526-j9kg00qf 2542 11 outer outer JJ cord-022526-j9kg00qf 2542 12 layer layer NN cord-022526-j9kg00qf 2542 13 becomes become VBZ cord-022526-j9kg00qf 2542 14 more more RBR cord-022526-j9kg00qf 2542 15 longitudinal longitudinal JJ cord-022526-j9kg00qf 2542 16 , , , cord-022526-j9kg00qf 2542 17 whereas whereas IN cord-022526-j9kg00qf 2542 18 the the DT cord-022526-j9kg00qf 2542 19 inner inner JJ cord-022526-j9kg00qf 2542 20 layer layer NN cord-022526-j9kg00qf 2542 21 thickens thicken VBZ cord-022526-j9kg00qf 2542 22 and and CC cord-022526-j9kg00qf 2542 23 becomes become VBZ cord-022526-j9kg00qf 2542 24 circular circular JJ cord-022526-j9kg00qf 2542 25 . . . cord-022526-j9kg00qf 2543 1 The the DT cord-022526-j9kg00qf 2543 2 wall wall NN cord-022526-j9kg00qf 2543 3 of of IN cord-022526-j9kg00qf 2543 4 the the DT cord-022526-j9kg00qf 2543 5 terminal terminal JJ cord-022526-j9kg00qf 2543 6 esophagus esophagus NN cord-022526-j9kg00qf 2543 7 can can MD cord-022526-j9kg00qf 2543 8 be be VB cord-022526-j9kg00qf 2543 9 1 1 CD cord-022526-j9kg00qf 2543 10 to to IN cord-022526-j9kg00qf 2543 11 2 2 CD cord-022526-j9kg00qf 2543 12 cm cm NN cord-022526-j9kg00qf 2543 13 thick thick JJ cord-022526-j9kg00qf 2543 14 . . . cord-022526-j9kg00qf 2544 1 Deep deep JJ cord-022526-j9kg00qf 2544 2 cervical cervical JJ cord-022526-j9kg00qf 2544 3 fascia fascia NN cord-022526-j9kg00qf 2544 4 , , , cord-022526-j9kg00qf 2544 5 pleura pleura NN cord-022526-j9kg00qf 2544 6 , , , cord-022526-j9kg00qf 2544 7 and and CC cord-022526-j9kg00qf 2544 8 peritoneum peritoneum NN cord-022526-j9kg00qf 2544 9 contribute contribute VBP cord-022526-j9kg00qf 2544 10 to to IN cord-022526-j9kg00qf 2544 11 the the DT cord-022526-j9kg00qf 2544 12 thin thin JJ cord-022526-j9kg00qf 2544 13 fibrous fibrous JJ cord-022526-j9kg00qf 2544 14 tunica tunica NNP cord-022526-j9kg00qf 2544 15 adventitia adventitia NN cord-022526-j9kg00qf 2544 16 of of IN cord-022526-j9kg00qf 2544 17 the the DT cord-022526-j9kg00qf 2544 18 esophagus esophagus NN cord-022526-j9kg00qf 2544 19 . . . cord-022526-j9kg00qf 2545 1 Motor motor NN cord-022526-j9kg00qf 2545 2 innervation innervation NN cord-022526-j9kg00qf 2545 3 to to IN cord-022526-j9kg00qf 2545 4 the the DT cord-022526-j9kg00qf 2545 5 striated striated JJ cord-022526-j9kg00qf 2545 6 skeletal skeletal JJ cord-022526-j9kg00qf 2545 7 muscle muscle NN cord-022526-j9kg00qf 2545 8 of of IN cord-022526-j9kg00qf 2545 9 the the DT cord-022526-j9kg00qf 2545 10 esophagus esophagus NN cord-022526-j9kg00qf 2545 11 includes include VBZ cord-022526-j9kg00qf 2545 12 the the DT cord-022526-j9kg00qf 2545 13 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2545 14 and and CC cord-022526-j9kg00qf 2545 15 esophageal esophageal JJ cord-022526-j9kg00qf 2545 16 branches branch NNS cord-022526-j9kg00qf 2545 17 of of IN cord-022526-j9kg00qf 2545 18 the the DT cord-022526-j9kg00qf 2545 19 vagus vagus NN cord-022526-j9kg00qf 2545 20 nerve nerve NN cord-022526-j9kg00qf 2545 21 , , , cord-022526-j9kg00qf 2545 22 which which WDT cord-022526-j9kg00qf 2545 23 originate originate VBP cord-022526-j9kg00qf 2545 24 in in IN cord-022526-j9kg00qf 2545 25 the the DT cord-022526-j9kg00qf 2545 26 nucleus nucleus NN cord-022526-j9kg00qf 2545 27 ambiguus ambiguus NN cord-022526-j9kg00qf 2545 28 of of IN cord-022526-j9kg00qf 2545 29 the the DT cord-022526-j9kg00qf 2545 30 medulla medulla NNP cord-022526-j9kg00qf 2545 31 oblongata oblongata NNP cord-022526-j9kg00qf 2545 32 . . . cord-022526-j9kg00qf 2546 1 Parasympathetic parasympathetic JJ cord-022526-j9kg00qf 2546 2 fibers fiber NNS cord-022526-j9kg00qf 2546 3 of of IN cord-022526-j9kg00qf 2546 4 the the DT cord-022526-j9kg00qf 2546 5 vagus vagus NNP cord-022526-j9kg00qf 2546 6 nerve nerve NN cord-022526-j9kg00qf 2546 7 supply supply VBP cord-022526-j9kg00qf 2546 8 the the DT cord-022526-j9kg00qf 2546 9 smooth smooth JJ cord-022526-j9kg00qf 2546 10 muscle muscle NN cord-022526-j9kg00qf 2546 11 of of IN cord-022526-j9kg00qf 2546 12 the the DT cord-022526-j9kg00qf 2546 13 distal distal JJ cord-022526-j9kg00qf 2546 14 esophagus esophagus NN cord-022526-j9kg00qf 2546 15 . . . cord-022526-j9kg00qf 2547 1 Sympathetic sympathetic JJ cord-022526-j9kg00qf 2547 2 innervation innervation NN cord-022526-j9kg00qf 2547 3 of of IN cord-022526-j9kg00qf 2547 4 the the DT cord-022526-j9kg00qf 2547 5 esophagus esophagus NN cord-022526-j9kg00qf 2547 6 is be VBZ cord-022526-j9kg00qf 2547 7 minimal minimal JJ cord-022526-j9kg00qf 2547 8 . . . cord-022526-j9kg00qf 2548 1 Passage passage NN cord-022526-j9kg00qf 2548 2 of of IN cord-022526-j9kg00qf 2548 3 ingesta ingesta NNP cord-022526-j9kg00qf 2548 4 through through IN cord-022526-j9kg00qf 2548 5 the the DT cord-022526-j9kg00qf 2548 6 esophagus esophagus NN cord-022526-j9kg00qf 2548 7 can can MD cord-022526-j9kg00qf 2548 8 be be VB cord-022526-j9kg00qf 2548 9 considered consider VBN cord-022526-j9kg00qf 2548 10 part part NN cord-022526-j9kg00qf 2548 11 of of IN cord-022526-j9kg00qf 2548 12 the the DT cord-022526-j9kg00qf 2548 13 swallowing swallowing NN cord-022526-j9kg00qf 2548 14 process process NN cord-022526-j9kg00qf 2548 15 , , , cord-022526-j9kg00qf 2548 16 which which WDT cord-022526-j9kg00qf 2548 17 consists consist VBZ cord-022526-j9kg00qf 2548 18 of of IN cord-022526-j9kg00qf 2548 19 oral oral JJ cord-022526-j9kg00qf 2548 20 , , , cord-022526-j9kg00qf 2548 21 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2548 22 , , , cord-022526-j9kg00qf 2548 23 and and CC cord-022526-j9kg00qf 2548 24 esophageal esophageal JJ cord-022526-j9kg00qf 2548 25 stages stage NNS cord-022526-j9kg00qf 2548 26 . . . cord-022526-j9kg00qf 2549 1 The the DT cord-022526-j9kg00qf 2549 2 oral oral JJ cord-022526-j9kg00qf 2549 3 stage stage NN cord-022526-j9kg00qf 2549 4 is be VBZ cord-022526-j9kg00qf 2549 5 voluntary voluntary JJ cord-022526-j9kg00qf 2549 6 and and CC cord-022526-j9kg00qf 2549 7 involves involve VBZ cord-022526-j9kg00qf 2549 8 transport transport NN cord-022526-j9kg00qf 2549 9 of of IN cord-022526-j9kg00qf 2549 10 the the DT cord-022526-j9kg00qf 2549 11 food food NN cord-022526-j9kg00qf 2549 12 bolus bolus NN cord-022526-j9kg00qf 2549 13 from from IN cord-022526-j9kg00qf 2549 14 the the DT cord-022526-j9kg00qf 2549 15 mouth mouth NN cord-022526-j9kg00qf 2549 16 into into IN cord-022526-j9kg00qf 2549 17 the the DT cord-022526-j9kg00qf 2549 18 oropharynx oropharynx NN cord-022526-j9kg00qf 2549 19 . . . cord-022526-j9kg00qf 2550 1 During during IN cord-022526-j9kg00qf 2550 2 the the DT cord-022526-j9kg00qf 2550 3 involuntary involuntary JJ cord-022526-j9kg00qf 2550 4 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2550 5 stage stage NN cord-022526-j9kg00qf 2550 6 the the DT cord-022526-j9kg00qf 2550 7 food food NN cord-022526-j9kg00qf 2550 8 bolus bolus NN cord-022526-j9kg00qf 2550 9 is be VBZ cord-022526-j9kg00qf 2550 10 forced force VBN cord-022526-j9kg00qf 2550 11 through through IN cord-022526-j9kg00qf 2550 12 the the DT cord-022526-j9kg00qf 2550 13 momentarily momentarily RB cord-022526-j9kg00qf 2550 14 relaxed relaxed JJ cord-022526-j9kg00qf 2550 15 upper upper JJ cord-022526-j9kg00qf 2550 16 esophageal esophageal JJ cord-022526-j9kg00qf 2550 17 sphincter sphincter NN cord-022526-j9kg00qf 2550 18 by by IN cord-022526-j9kg00qf 2550 19 simultaneous simultaneous JJ cord-022526-j9kg00qf 2550 20 contractions contraction NNS cord-022526-j9kg00qf 2550 21 of of IN cord-022526-j9kg00qf 2550 22 the the DT cord-022526-j9kg00qf 2550 23 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 2550 24 muscles muscle NNS cord-022526-j9kg00qf 2550 25 . . . cord-022526-j9kg00qf 2551 1 In in IN cord-022526-j9kg00qf 2551 2 the the DT cord-022526-j9kg00qf 2551 3 esophageal esophageal JJ cord-022526-j9kg00qf 2551 4 phase phase NN cord-022526-j9kg00qf 2551 5 of of IN cord-022526-j9kg00qf 2551 6 swallowing swallow VBG cord-022526-j9kg00qf 2551 7 the the DT cord-022526-j9kg00qf 2551 8 upper upper JJ cord-022526-j9kg00qf 2551 9 esophageal esophageal JJ cord-022526-j9kg00qf 2551 10 sphincter sphincter NN cord-022526-j9kg00qf 2551 11 closes close VBZ cord-022526-j9kg00qf 2551 12 immediately immediately RB cord-022526-j9kg00qf 2551 13 , , , cord-022526-j9kg00qf 2551 14 the the DT cord-022526-j9kg00qf 2551 15 lower low JJR cord-022526-j9kg00qf 2551 16 esophageal esophageal JJ cord-022526-j9kg00qf 2551 17 sphincter sphincter NN cord-022526-j9kg00qf 2551 18 opens open VBZ cord-022526-j9kg00qf 2551 19 , , , cord-022526-j9kg00qf 2551 20 and and CC cord-022526-j9kg00qf 2551 21 esophageal esophageal JJ cord-022526-j9kg00qf 2551 22 peristalsis peristalsis NN cord-022526-j9kg00qf 2551 23 propels propel VBZ cord-022526-j9kg00qf 2551 24 the the DT cord-022526-j9kg00qf 2551 25 bolus bolus NN cord-022526-j9kg00qf 2551 26 into into IN cord-022526-j9kg00qf 2551 27 the the DT cord-022526-j9kg00qf 2551 28 stomach stomach NN cord-022526-j9kg00qf 2551 29 . . . cord-022526-j9kg00qf 2552 1 2 2 LS cord-022526-j9kg00qf 2553 1 Unlike unlike IN cord-022526-j9kg00qf 2553 2 a a DT cord-022526-j9kg00qf 2553 3 food food NN cord-022526-j9kg00qf 2553 4 bolus bolus NN cord-022526-j9kg00qf 2553 5 , , , cord-022526-j9kg00qf 2553 6 liquids liquid NNS cord-022526-j9kg00qf 2553 7 do do VBP cord-022526-j9kg00qf 2553 8 not not RB cord-022526-j9kg00qf 2553 9 require require VB cord-022526-j9kg00qf 2553 10 peristalsis peristalsis NN cord-022526-j9kg00qf 2553 11 to to TO cord-022526-j9kg00qf 2553 12 reach reach VB cord-022526-j9kg00qf 2553 13 the the DT cord-022526-j9kg00qf 2553 14 lower low JJR cord-022526-j9kg00qf 2553 15 esophageal esophageal JJ cord-022526-j9kg00qf 2553 16 sphincter sphincter NN cord-022526-j9kg00qf 2553 17 and and CC cord-022526-j9kg00qf 2553 18 may may MD cord-022526-j9kg00qf 2553 19 precede precede VB cord-022526-j9kg00qf 2553 20 the the DT cord-022526-j9kg00qf 2553 21 food food NN cord-022526-j9kg00qf 2553 22 bolus bolus NN cord-022526-j9kg00qf 2553 23 during during IN cord-022526-j9kg00qf 2553 24 swallowing swallowing NN cord-022526-j9kg00qf 2553 25 . . . cord-022526-j9kg00qf 2554 1 The the DT cord-022526-j9kg00qf 2554 2 upper upper JJ cord-022526-j9kg00qf 2554 3 esophageal esophageal JJ cord-022526-j9kg00qf 2554 4 sphincter sphincter NN cord-022526-j9kg00qf 2554 5 prevents prevent VBZ cord-022526-j9kg00qf 2554 6 esophagopharyngeal esophagopharyngeal JJ cord-022526-j9kg00qf 2554 7 reflux reflux NN cord-022526-j9kg00qf 2554 8 during during IN cord-022526-j9kg00qf 2554 9 swallowing swallow VBG cord-022526-j9kg00qf 2554 10 and and CC cord-022526-j9kg00qf 2554 11 air air NN cord-022526-j9kg00qf 2554 12 distention distention NN cord-022526-j9kg00qf 2554 13 of of IN cord-022526-j9kg00qf 2554 14 the the DT cord-022526-j9kg00qf 2554 15 esophagus esophagus NN cord-022526-j9kg00qf 2554 16 during during IN cord-022526-j9kg00qf 2554 17 inspiration inspiration NN cord-022526-j9kg00qf 2554 18 . . . cord-022526-j9kg00qf 2555 1 Upper upper JJ cord-022526-j9kg00qf 2555 2 esophageal esophageal JJ cord-022526-j9kg00qf 2555 3 pressure pressure NN cord-022526-j9kg00qf 2555 4 increases increase NNS cord-022526-j9kg00qf 2555 5 in in IN cord-022526-j9kg00qf 2555 6 response response NN cord-022526-j9kg00qf 2555 7 to to TO cord-022526-j9kg00qf 2555 8 pressure pressure NN cord-022526-j9kg00qf 2555 9 from from IN cord-022526-j9kg00qf 2555 10 a a DT cord-022526-j9kg00qf 2555 11 food food NN cord-022526-j9kg00qf 2555 12 bolus bolus NN cord-022526-j9kg00qf 2555 13 and and CC cord-022526-j9kg00qf 2555 14 to to IN cord-022526-j9kg00qf 2555 15 increased increase VBN cord-022526-j9kg00qf 2555 16 intraluminal intraluminal JJ cord-022526-j9kg00qf 2555 17 acidity acidity NN cord-022526-j9kg00qf 2555 18 , , , cord-022526-j9kg00qf 2555 19 as as IN cord-022526-j9kg00qf 2555 20 would would MD cord-022526-j9kg00qf 2555 21 occur occur VB cord-022526-j9kg00qf 2555 22 with with IN cord-022526-j9kg00qf 2555 23 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2555 24 reflux reflux NN cord-022526-j9kg00qf 2555 25 . . . cord-022526-j9kg00qf 2556 1 The the DT cord-022526-j9kg00qf 2556 2 lower low JJR cord-022526-j9kg00qf 2556 3 esophageal esophageal JJ cord-022526-j9kg00qf 2556 4 sphincter sphincter NN cord-022526-j9kg00qf 2556 5 is be VBZ cord-022526-j9kg00qf 2556 6 a a DT cord-022526-j9kg00qf 2556 7 smooth smooth JJ cord-022526-j9kg00qf 2556 8 muscle muscle NN cord-022526-j9kg00qf 2556 9 located locate VBN cord-022526-j9kg00qf 2556 10 at at IN cord-022526-j9kg00qf 2556 11 the the DT cord-022526-j9kg00qf 2556 12 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2556 13 junction junction NN cord-022526-j9kg00qf 2556 14 that that WDT cord-022526-j9kg00qf 2556 15 is be VBZ cord-022526-j9kg00qf 2556 16 morphologically morphologically RB cord-022526-j9kg00qf 2556 17 ill ill RB cord-022526-j9kg00qf 2556 18 defined define VBN cord-022526-j9kg00qf 2556 19 but but CC cord-022526-j9kg00qf 2556 20 forms form VBZ cord-022526-j9kg00qf 2556 21 an an DT cord-022526-j9kg00qf 2556 22 effective effective JJ cord-022526-j9kg00qf 2556 23 functional functional JJ cord-022526-j9kg00qf 2556 24 barrier barrier NN cord-022526-j9kg00qf 2556 25 . . . cord-022526-j9kg00qf 2557 1 2 2 LS cord-022526-j9kg00qf 2558 1 Normally normally RB cord-022526-j9kg00qf 2558 2 the the DT cord-022526-j9kg00qf 2558 3 lower low JJR cord-022526-j9kg00qf 2558 4 esophageal esophageal JJ cord-022526-j9kg00qf 2558 5 sphincter sphincter NN cord-022526-j9kg00qf 2558 6 is be VBZ cord-022526-j9kg00qf 2558 7 closed close VBN cord-022526-j9kg00qf 2558 8 in in IN cord-022526-j9kg00qf 2558 9 response response NN cord-022526-j9kg00qf 2558 10 to to IN cord-022526-j9kg00qf 2558 11 gastric gastric JJ cord-022526-j9kg00qf 2558 12 distention distention NN cord-022526-j9kg00qf 2558 13 to to TO cord-022526-j9kg00qf 2558 14 restrict restrict VB cord-022526-j9kg00qf 2558 15 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2558 16 reflux reflux NN cord-022526-j9kg00qf 2558 17 . . . cord-022526-j9kg00qf 2559 1 Relaxation relaxation NN cord-022526-j9kg00qf 2559 2 of of IN cord-022526-j9kg00qf 2559 3 the the DT cord-022526-j9kg00qf 2559 4 lower low JJR cord-022526-j9kg00qf 2559 5 esophageal esophageal JJ cord-022526-j9kg00qf 2559 6 sphincter sphincter NN cord-022526-j9kg00qf 2559 7 permits permit VBZ cord-022526-j9kg00qf 2559 8 passage passage NN cord-022526-j9kg00qf 2559 9 of of IN cord-022526-j9kg00qf 2559 10 ingested ingest VBN cord-022526-j9kg00qf 2559 11 material material NN cord-022526-j9kg00qf 2559 12 from from IN cord-022526-j9kg00qf 2559 13 the the DT cord-022526-j9kg00qf 2559 14 esophagus esophagus NN cord-022526-j9kg00qf 2559 15 to to IN cord-022526-j9kg00qf 2559 16 the the DT cord-022526-j9kg00qf 2559 17 stomach stomach NN cord-022526-j9kg00qf 2559 18 . . . cord-022526-j9kg00qf 2560 1 Distention Distention NNP cord-022526-j9kg00qf 2560 2 of of IN cord-022526-j9kg00qf 2560 3 the the DT cord-022526-j9kg00qf 2560 4 stomach stomach NN cord-022526-j9kg00qf 2560 5 with with IN cord-022526-j9kg00qf 2560 6 ingesta ingesta NNP cord-022526-j9kg00qf 2560 7 mechanically mechanically RB cord-022526-j9kg00qf 2560 8 constricts constrict VBZ cord-022526-j9kg00qf 2560 9 the the DT cord-022526-j9kg00qf 2560 10 lower low JJR cord-022526-j9kg00qf 2560 11 esophageal esophageal JJ cord-022526-j9kg00qf 2560 12 sphincter sphincter NN cord-022526-j9kg00qf 2560 13 . . . cord-022526-j9kg00qf 2561 1 Gastric gastric JJ cord-022526-j9kg00qf 2561 2 distention distention NN cord-022526-j9kg00qf 2561 3 also also RB cord-022526-j9kg00qf 2561 4 triggers trigger VBZ cord-022526-j9kg00qf 2561 5 a a DT cord-022526-j9kg00qf 2561 6 _SP cord-022526-j9kg00qf 2561 7 The the DT cord-022526-j9kg00qf 2561 8 esophagus esophagus NN cord-022526-j9kg00qf 2561 9 is be VBZ cord-022526-j9kg00qf 2561 10 a a DT cord-022526-j9kg00qf 2561 11 musculomembranous musculomembranous JJ cord-022526-j9kg00qf 2561 12 tube tube NN cord-022526-j9kg00qf 2561 13 that that WDT cord-022526-j9kg00qf 2561 14 originates originate VBZ cord-022526-j9kg00qf 2561 15 from from IN cord-022526-j9kg00qf 2561 16 the the DT cord-022526-j9kg00qf 2561 17 pharynx pharynx NN cord-022526-j9kg00qf 2561 18 dorsal dorsal JJ cord-022526-j9kg00qf 2561 19 to to IN cord-022526-j9kg00qf 2561 20 the the DT cord-022526-j9kg00qf 2561 21 larynx larynx NN cord-022526-j9kg00qf 2561 22 and and CC cord-022526-j9kg00qf 2561 23 terminates terminate VBZ cord-022526-j9kg00qf 2561 24 at at IN cord-022526-j9kg00qf 2561 25 the the DT cord-022526-j9kg00qf 2561 26 cardia cardia NN cord-022526-j9kg00qf 2561 27 of of IN cord-022526-j9kg00qf 2561 28 the the DT cord-022526-j9kg00qf 2561 29 stomach stomach NN cord-022526-j9kg00qf 2561 30 . . . cord-022526-j9kg00qf 2562 1 1 1 LS cord-022526-j9kg00qf 2563 1 In in IN cord-022526-j9kg00qf 2563 2 adult adult NN cord-022526-j9kg00qf 2563 3 Thoroughbred thoroughbred JJ cord-022526-j9kg00qf 2563 4 horses horse NNS cord-022526-j9kg00qf 2564 1 the the DT cord-022526-j9kg00qf 2564 2 esophagus esophagus NN cord-022526-j9kg00qf 2564 3 is be VBZ cord-022526-j9kg00qf 2564 4 approximately approximately RB cord-022526-j9kg00qf 2564 5 120 120 CD cord-022526-j9kg00qf 2564 6 cm cm NNS cord-022526-j9kg00qf 2564 7 long long RB cord-022526-j9kg00qf 2564 8 . . . cord-022526-j9kg00qf 2565 1 The the DT cord-022526-j9kg00qf 2565 2 cervical cervical JJ cord-022526-j9kg00qf 2565 3 portion portion NN cord-022526-j9kg00qf 2565 4 is be VBZ cord-022526-j9kg00qf 2565 5 approximately approximately RB cord-022526-j9kg00qf 2565 6 70 70 CD cord-022526-j9kg00qf 2565 7 cm cm NNS cord-022526-j9kg00qf 2565 8 long long RB cord-022526-j9kg00qf 2565 9 ; ; : cord-022526-j9kg00qf 2565 10 the the DT cord-022526-j9kg00qf 2565 11 thoracic thoracic JJ cord-022526-j9kg00qf 2565 12 portion portion NN cord-022526-j9kg00qf 2565 13 , , , cord-022526-j9kg00qf 2565 14 approximately approximately RB cord-022526-j9kg00qf 2565 15 50 50 CD cord-022526-j9kg00qf 2565 16 cm cm NNS cord-022526-j9kg00qf 2565 17 long long JJ cord-022526-j9kg00qf 2565 18 ; ; : cord-022526-j9kg00qf 2565 19 and and CC cord-022526-j9kg00qf 2565 20 the the DT cord-022526-j9kg00qf 2565 21 short short JJ cord-022526-j9kg00qf 2565 22 abdominal abdominal JJ cord-022526-j9kg00qf 2565 23 portion portion NN cord-022526-j9kg00qf 2565 24 , , , cord-022526-j9kg00qf 2565 25 only only RB cord-022526-j9kg00qf 2565 26 approximately approximately RB cord-022526-j9kg00qf 2565 27 2 2 CD cord-022526-j9kg00qf 2565 28 cm cm NNS cord-022526-j9kg00qf 2565 29 long long RB cord-022526-j9kg00qf 2565 30 . . . cord-022526-j9kg00qf 2566 1 The the DT cord-022526-j9kg00qf 2566 2 cervical cervical JJ cord-022526-j9kg00qf 2566 3 esophagus esophagus NN cord-022526-j9kg00qf 2566 4 generally generally RB cord-022526-j9kg00qf 2566 5 lies lie VBZ cord-022526-j9kg00qf 2566 6 dorsal dorsal JJ cord-022526-j9kg00qf 2566 7 and and CC cord-022526-j9kg00qf 2566 8 to to IN cord-022526-j9kg00qf 2566 9 the the DT cord-022526-j9kg00qf 2566 10 left left NN cord-022526-j9kg00qf 2566 11 of of IN cord-022526-j9kg00qf 2566 12 the the DT cord-022526-j9kg00qf 2566 13 trachea trachea NN cord-022526-j9kg00qf 2566 14 in in IN cord-022526-j9kg00qf 2566 15 the the DT cord-022526-j9kg00qf 2566 16 cervical cervical JJ cord-022526-j9kg00qf 2566 17 region region NN cord-022526-j9kg00qf 2566 18 . . . cord-022526-j9kg00qf 2567 1 In in IN cord-022526-j9kg00qf 2567 2 the the DT cord-022526-j9kg00qf 2567 3 thorax thorax NN cord-022526-j9kg00qf 2567 4 the the DT cord-022526-j9kg00qf 2567 5 esophagus esophagus NN cord-022526-j9kg00qf 2567 6 courses course NNS cord-022526-j9kg00qf 2567 7 through through IN cord-022526-j9kg00qf 2567 8 the the DT cord-022526-j9kg00qf 2567 9 mediastinum mediastinum NN cord-022526-j9kg00qf 2567 10 lying lie VBG cord-022526-j9kg00qf 2567 11 dorsal dorsal JJ cord-022526-j9kg00qf 2567 12 to to IN cord-022526-j9kg00qf 2567 13 the the DT cord-022526-j9kg00qf 2567 14 trachea trachea NN cord-022526-j9kg00qf 2567 15 and and CC cord-022526-j9kg00qf 2567 16 crosses cross VBZ cord-022526-j9kg00qf 2567 17 to to IN cord-022526-j9kg00qf 2567 18 the the DT cord-022526-j9kg00qf 2567 19 right right NN cord-022526-j9kg00qf 2567 20 of of IN cord-022526-j9kg00qf 2567 21 the the DT cord-022526-j9kg00qf 2567 22 aortic aortic JJ cord-022526-j9kg00qf 2567 23 arch arch NN cord-022526-j9kg00qf 2567 24 dorsal dorsal NN cord-022526-j9kg00qf 2567 25 to to IN cord-022526-j9kg00qf 2567 26 the the DT cord-022526-j9kg00qf 2567 27 heart heart NN cord-022526-j9kg00qf 2567 28 base base NN cord-022526-j9kg00qf 2567 29 . . . cord-022526-j9kg00qf 2568 1 impactions impaction NNS cord-022526-j9kg00qf 2568 2 . . . cord-022526-j9kg00qf 2569 1 Intramural intramural JJ cord-022526-j9kg00qf 2569 2 causes cause NNS cord-022526-j9kg00qf 2569 3 of of IN cord-022526-j9kg00qf 2569 4 esophageal esophageal JJ cord-022526-j9kg00qf 2569 5 obstruction obstruction NN cord-022526-j9kg00qf 2569 6 include include VBP cord-022526-j9kg00qf 2569 7 tumors tumor NNS cord-022526-j9kg00qf 2569 8 ( ( -LRB- cord-022526-j9kg00qf 2569 9 squamous squamous JJ cord-022526-j9kg00qf 2569 10 cell cell NN cord-022526-j9kg00qf 2569 11 carcinoma carcinoma NN cord-022526-j9kg00qf 2569 12 ) ) -RRB- cord-022526-j9kg00qf 2569 13 , , , cord-022526-j9kg00qf 2569 14 strictures stricture NNS cord-022526-j9kg00qf 2569 15 , , , cord-022526-j9kg00qf 2569 16 diverticula diverticula NN cord-022526-j9kg00qf 2569 17 , , , cord-022526-j9kg00qf 2569 18 and and CC cord-022526-j9kg00qf 2569 19 cysts cyst NNS cord-022526-j9kg00qf 2569 20 . . . cord-022526-j9kg00qf 2570 1 [ [ -LRB- cord-022526-j9kg00qf 2570 2 3 3 CD cord-022526-j9kg00qf 2570 3 ] ] -RRB- cord-022526-j9kg00qf 2570 4 [ [ -LRB- cord-022526-j9kg00qf 2570 5 4 4 CD cord-022526-j9kg00qf 2570 6 ] ] -RRB- cord-022526-j9kg00qf 2570 7 [ [ -LRB- cord-022526-j9kg00qf 2570 8 5 5 CD cord-022526-j9kg00qf 2570 9 ] ] -RRB- cord-022526-j9kg00qf 2570 10 [ [ -LRB- cord-022526-j9kg00qf 2570 11 6 6 CD cord-022526-j9kg00qf 2570 12 ] ] -RRB- cord-022526-j9kg00qf 2570 13 [ [ -LRB- cord-022526-j9kg00qf 2570 14 7 7 CD cord-022526-j9kg00qf 2570 15 ] ] -RRB- cord-022526-j9kg00qf 2571 1 [ [ -LRB- cord-022526-j9kg00qf 2571 2 8 8 CD cord-022526-j9kg00qf 2571 3 ] ] -RRB- cord-022526-j9kg00qf 2571 4 [ [ -LRB- cord-022526-j9kg00qf 2571 5 9 9 CD cord-022526-j9kg00qf 2571 6 ] ] -RRB- cord-022526-j9kg00qf 2572 1 [ [ -LRB- cord-022526-j9kg00qf 2572 2 10 10 CD cord-022526-j9kg00qf 2572 3 ] ] -RRB- cord-022526-j9kg00qf 2572 4 Mediastinal Mediastinal NNP cord-022526-j9kg00qf 2572 5 or or CC cord-022526-j9kg00qf 2572 6 cervical cervical JJ cord-022526-j9kg00qf 2572 7 masses masse NNS cord-022526-j9kg00qf 2572 8 ( ( -LRB- cord-022526-j9kg00qf 2572 9 tumors tumor NNS cord-022526-j9kg00qf 2572 10 or or CC cord-022526-j9kg00qf 2572 11 abscesses abscess NNS cord-022526-j9kg00qf 2572 12 ) ) -RRB- cord-022526-j9kg00qf 2572 13 may may MD cord-022526-j9kg00qf 2572 14 cause cause VB cord-022526-j9kg00qf 2572 15 extramural extramural JJ cord-022526-j9kg00qf 2572 16 obstructions obstruction NNS cord-022526-j9kg00qf 2572 17 . . . cord-022526-j9kg00qf 2573 1 Congenital congenital JJ cord-022526-j9kg00qf 2573 2 anomalies anomaly NNS cord-022526-j9kg00qf 2573 3 are be VBP cord-022526-j9kg00qf 2573 4 covered cover VBN cord-022526-j9kg00qf 2573 5 in in IN cord-022526-j9kg00qf 2573 6 detail detail NN cord-022526-j9kg00qf 2573 7 later later RB cord-022526-j9kg00qf 2573 8 . . . cord-022526-j9kg00qf 2574 1 The the DT cord-022526-j9kg00qf 2574 2 clinician clinician NN cord-022526-j9kg00qf 2574 3 must must MD cord-022526-j9kg00qf 2574 4 perform perform VB cord-022526-j9kg00qf 2574 5 a a DT cord-022526-j9kg00qf 2574 6 thorough thorough JJ cord-022526-j9kg00qf 2574 7 physical physical JJ cord-022526-j9kg00qf 2574 8 examination examination NN cord-022526-j9kg00qf 2574 9 , , , cord-022526-j9kg00qf 2574 10 including include VBG cord-022526-j9kg00qf 2574 11 complete complete JJ cord-022526-j9kg00qf 2574 12 oral oral JJ cord-022526-j9kg00qf 2574 13 and and CC cord-022526-j9kg00qf 2574 14 neurologic neurologic JJ cord-022526-j9kg00qf 2574 15 examination examination NN cord-022526-j9kg00qf 2574 16 , , , cord-022526-j9kg00qf 2574 17 to to TO cord-022526-j9kg00qf 2574 18 help help VB cord-022526-j9kg00qf 2574 19 rule rule VB cord-022526-j9kg00qf 2574 20 out out RP cord-022526-j9kg00qf 2574 21 causes cause NNS cord-022526-j9kg00qf 2574 22 of of IN cord-022526-j9kg00qf 2574 23 dysphagia dysphagia NN cord-022526-j9kg00qf 2574 24 and and CC cord-022526-j9kg00qf 2574 25 nasal nasal NN cord-022526-j9kg00qf 2574 26 discharge discharge NN cord-022526-j9kg00qf 2574 27 other other JJ cord-022526-j9kg00qf 2574 28 than than IN cord-022526-j9kg00qf 2574 29 esophageal esophageal JJ cord-022526-j9kg00qf 2574 30 obstruction obstruction NN cord-022526-j9kg00qf 2574 31 . . . cord-022526-j9kg00qf 2575 1 The the DT cord-022526-j9kg00qf 2575 2 clinical clinical JJ cord-022526-j9kg00qf 2575 3 signs sign NNS cord-022526-j9kg00qf 2575 4 associated associate VBN cord-022526-j9kg00qf 2575 5 with with IN cord-022526-j9kg00qf 2575 6 esophageal esophageal JJ cord-022526-j9kg00qf 2575 7 obstructions obstruction NNS cord-022526-j9kg00qf 2575 8 are be VBP cord-022526-j9kg00qf 2575 9 related relate VBN cord-022526-j9kg00qf 2575 10 primarily primarily RB cord-022526-j9kg00qf 2575 11 to to IN cord-022526-j9kg00qf 2575 12 regurgitation regurgitation NN cord-022526-j9kg00qf 2575 13 of of IN cord-022526-j9kg00qf 2575 14 food food NN cord-022526-j9kg00qf 2575 15 , , , cord-022526-j9kg00qf 2575 16 water water NN cord-022526-j9kg00qf 2575 17 , , , cord-022526-j9kg00qf 2575 18 and and CC cord-022526-j9kg00qf 2575 19 saliva saliva NN cord-022526-j9kg00qf 2575 20 caused cause VBN cord-022526-j9kg00qf 2575 21 by by IN cord-022526-j9kg00qf 2575 22 esophageal esophageal JJ cord-022526-j9kg00qf 2575 23 ( ( -LRB- cord-022526-j9kg00qf 2575 24 postpharyngeal postpharyngeal NN cord-022526-j9kg00qf 2575 25 ) ) -RRB- cord-022526-j9kg00qf 2575 26 dysphagia dysphagia NN cord-022526-j9kg00qf 2575 27 . . . cord-022526-j9kg00qf 2576 1 11 11 CD cord-022526-j9kg00qf 2576 2 Horses horse NNS cord-022526-j9kg00qf 2576 3 with with IN cord-022526-j9kg00qf 2576 4 esophageal esophageal JJ cord-022526-j9kg00qf 2576 5 obstruction obstruction NN cord-022526-j9kg00qf 2576 6 are be VBP cord-022526-j9kg00qf 2576 7 often often RB cord-022526-j9kg00qf 2576 8 anxious anxious JJ cord-022526-j9kg00qf 2576 9 and and CC cord-022526-j9kg00qf 2576 10 stand stand VBP cord-022526-j9kg00qf 2576 11 with with IN cord-022526-j9kg00qf 2576 12 their -PRON- PRP$ cord-022526-j9kg00qf 2576 13 neck neck NN cord-022526-j9kg00qf 2576 14 extended extend VBN cord-022526-j9kg00qf 2576 15 . . . cord-022526-j9kg00qf 2577 1 One one CD cord-022526-j9kg00qf 2577 2 may may MD cord-022526-j9kg00qf 2577 3 note note VB cord-022526-j9kg00qf 2577 4 gagging gagging NN cord-022526-j9kg00qf 2577 5 or or CC cord-022526-j9kg00qf 2577 6 retching retching NN cord-022526-j9kg00qf 2577 7 , , , cord-022526-j9kg00qf 2577 8 particularly particularly RB cord-022526-j9kg00qf 2577 9 with with IN cord-022526-j9kg00qf 2577 10 acute acute JJ cord-022526-j9kg00qf 2577 11 proximal proximal JJ cord-022526-j9kg00qf 2577 12 obstructions obstruction NNS cord-022526-j9kg00qf 2577 13 . . . cord-022526-j9kg00qf 2578 1 Bilateral bilateral JJ cord-022526-j9kg00qf 2578 2 frothy frothy JJ cord-022526-j9kg00qf 2578 3 nasal nasal NN cord-022526-j9kg00qf 2578 4 discharge discharge NN cord-022526-j9kg00qf 2578 5 containing contain VBG cord-022526-j9kg00qf 2578 6 saliva saliva NN cord-022526-j9kg00qf 2578 7 , , , cord-022526-j9kg00qf 2578 8 water water NN cord-022526-j9kg00qf 2578 9 , , , cord-022526-j9kg00qf 2578 10 and and CC cord-022526-j9kg00qf 2578 11 food food NN cord-022526-j9kg00qf 2578 12 material material NN cord-022526-j9kg00qf 2578 13 ; ; : cord-022526-j9kg00qf 2578 14 coughing cough VBG cord-022526-j9kg00qf 2578 15 ; ; : cord-022526-j9kg00qf 2578 16 odynophagia odynophagia NNP cord-022526-j9kg00qf 2578 17 ; ; : cord-022526-j9kg00qf 2578 18 and and CC cord-022526-j9kg00qf 2578 19 ptyalism ptyalism NN cord-022526-j9kg00qf 2578 20 are be VBP cord-022526-j9kg00qf 2578 21 characteristic characteristic JJ cord-022526-j9kg00qf 2578 22 clinical clinical JJ cord-022526-j9kg00qf 2578 23 signs sign NNS cord-022526-j9kg00qf 2578 24 , , , cord-022526-j9kg00qf 2578 25 the the DT cord-022526-j9kg00qf 2578 26 severity severity NN cord-022526-j9kg00qf 2578 27 of of IN cord-022526-j9kg00qf 2578 28 which which WDT cord-022526-j9kg00qf 2578 29 varies vary VBZ cord-022526-j9kg00qf 2578 30 with with IN cord-022526-j9kg00qf 2578 31 the the DT cord-022526-j9kg00qf 2578 32 degree degree NN cord-022526-j9kg00qf 2578 33 and and CC cord-022526-j9kg00qf 2578 34 location location NN cord-022526-j9kg00qf 2578 35 of of IN cord-022526-j9kg00qf 2578 36 the the DT cord-022526-j9kg00qf 2578 37 obstruction obstruction NN cord-022526-j9kg00qf 2578 38 . . . cord-022526-j9kg00qf 2579 1 Distention Distention NNP cord-022526-j9kg00qf 2579 2 in in IN cord-022526-j9kg00qf 2579 3 the the DT cord-022526-j9kg00qf 2579 4 jugular jugular NN cord-022526-j9kg00qf 2579 5 furrow furrow NN cord-022526-j9kg00qf 2579 6 may may MD cord-022526-j9kg00qf 2579 7 be be VB cord-022526-j9kg00qf 2579 8 evident evident JJ cord-022526-j9kg00qf 2579 9 at at IN cord-022526-j9kg00qf 2579 10 the the DT cord-022526-j9kg00qf 2579 11 site site NN cord-022526-j9kg00qf 2579 12 of of IN cord-022526-j9kg00qf 2579 13 obstruction obstruction NN cord-022526-j9kg00qf 2579 14 . . . cord-022526-j9kg00qf 2580 1 One one CD cord-022526-j9kg00qf 2580 2 may may MD cord-022526-j9kg00qf 2580 3 observe observe VB cord-022526-j9kg00qf 2580 4 other other JJ cord-022526-j9kg00qf 2580 5 clinical clinical JJ cord-022526-j9kg00qf 2580 6 signs sign NNS cord-022526-j9kg00qf 2580 7 related relate VBN cord-022526-j9kg00qf 2580 8 to to IN cord-022526-j9kg00qf 2580 9 regurgitation regurgitation NN cord-022526-j9kg00qf 2580 10 of of IN cord-022526-j9kg00qf 2580 11 saliva saliva NN cord-022526-j9kg00qf 2580 12 , , , cord-022526-j9kg00qf 2580 13 water water NN cord-022526-j9kg00qf 2580 14 , , , cord-022526-j9kg00qf 2580 15 and and CC cord-022526-j9kg00qf 2580 16 food food NN cord-022526-j9kg00qf 2580 17 material material NN cord-022526-j9kg00qf 2580 18 , , , cord-022526-j9kg00qf 2580 19 such such JJ cord-022526-j9kg00qf 2580 20 as as IN cord-022526-j9kg00qf 2580 21 dehydration dehydration NN cord-022526-j9kg00qf 2580 22 , , , cord-022526-j9kg00qf 2580 23 electrolyte electrolyte NN cord-022526-j9kg00qf 2580 24 or or CC cord-022526-j9kg00qf 2580 25 acid acid NN cord-022526-j9kg00qf 2580 26 - - HYPH cord-022526-j9kg00qf 2580 27 base base NN cord-022526-j9kg00qf 2580 28 imbalances imbalance NNS cord-022526-j9kg00qf 2580 29 , , , cord-022526-j9kg00qf 2580 30 weight weight NN cord-022526-j9kg00qf 2580 31 loss loss NN cord-022526-j9kg00qf 2580 32 , , , cord-022526-j9kg00qf 2580 33 and and CC cord-022526-j9kg00qf 2580 34 aspiration aspiration NN cord-022526-j9kg00qf 2580 35 pneumonia pneumonia NN cord-022526-j9kg00qf 2580 36 . . . cord-022526-j9kg00qf 2581 1 In in IN cord-022526-j9kg00qf 2581 2 extreme extreme JJ cord-022526-j9kg00qf 2581 3 cases case NNS cord-022526-j9kg00qf 2581 4 , , , cord-022526-j9kg00qf 2581 5 pressure pressure NN cord-022526-j9kg00qf 2581 6 necrosis necrosis NN cord-022526-j9kg00qf 2581 7 from from IN cord-022526-j9kg00qf 2581 8 the the DT cord-022526-j9kg00qf 2581 9 impaction impaction NN cord-022526-j9kg00qf 2581 10 or or CC cord-022526-j9kg00qf 2581 11 trauma trauma NN cord-022526-j9kg00qf 2581 12 to to IN cord-022526-j9kg00qf 2581 13 the the DT cord-022526-j9kg00qf 2581 14 esophagus esophagus NN cord-022526-j9kg00qf 2581 15 may may MD cord-022526-j9kg00qf 2581 16 cause cause VB cord-022526-j9kg00qf 2581 17 esophageal esophageal JJ cord-022526-j9kg00qf 2581 18 rupture rupture NN cord-022526-j9kg00qf 2581 19 . . . cord-022526-j9kg00qf 2582 1 If if IN cord-022526-j9kg00qf 2582 2 the the DT cord-022526-j9kg00qf 2582 3 rupture rupture NN cord-022526-j9kg00qf 2582 4 is be VBZ cord-022526-j9kg00qf 2582 5 in in IN cord-022526-j9kg00qf 2582 6 the the DT cord-022526-j9kg00qf 2582 7 cervical cervical JJ cord-022526-j9kg00qf 2582 8 esophagus esophagus NN cord-022526-j9kg00qf 2582 9 , , , cord-022526-j9kg00qf 2582 10 crepitus crepitus NN cord-022526-j9kg00qf 2582 11 or or CC cord-022526-j9kg00qf 2582 12 cellulitis cellulitis NN cord-022526-j9kg00qf 2582 13 may may MD cord-022526-j9kg00qf 2582 14 be be VB cord-022526-j9kg00qf 2582 15 evident evident JJ cord-022526-j9kg00qf 2582 16 along along IN cord-022526-j9kg00qf 2582 17 with with IN cord-022526-j9kg00qf 2582 18 signs sign NNS cord-022526-j9kg00qf 2582 19 of of IN cord-022526-j9kg00qf 2582 20 systemic systemic JJ cord-022526-j9kg00qf 2582 21 inflammation inflammation NN cord-022526-j9kg00qf 2582 22 . . . cord-022526-j9kg00qf 2583 1 Thoracic thoracic JJ cord-022526-j9kg00qf 2583 2 auscultation auscultation NN cord-022526-j9kg00qf 2583 3 is be VBZ cord-022526-j9kg00qf 2583 4 important important JJ cord-022526-j9kg00qf 2583 5 to to TO cord-022526-j9kg00qf 2583 6 determine determine VB cord-022526-j9kg00qf 2583 7 whether whether IN cord-022526-j9kg00qf 2583 8 aspiration aspiration NN cord-022526-j9kg00qf 2583 9 pneumonia pneumonia NN cord-022526-j9kg00qf 2583 10 is be VBZ cord-022526-j9kg00qf 2583 11 present present JJ cord-022526-j9kg00qf 2583 12 . . . cord-022526-j9kg00qf 2584 1 Intrathoracic intrathoracic JJ cord-022526-j9kg00qf 2584 2 esophageal esophageal JJ cord-022526-j9kg00qf 2584 3 rupture rupture NN cord-022526-j9kg00qf 2584 4 may may MD cord-022526-j9kg00qf 2584 5 result result VB cord-022526-j9kg00qf 2584 6 in in IN cord-022526-j9kg00qf 2584 7 pleuritis pleuritis NN cord-022526-j9kg00qf 2584 8 and and CC cord-022526-j9kg00qf 2584 9 its -PRON- PRP$ cord-022526-j9kg00qf 2584 10 associated associate VBN cord-022526-j9kg00qf 2584 11 clinical clinical JJ cord-022526-j9kg00qf 2584 12 signs sign NNS cord-022526-j9kg00qf 2584 13 . . . cord-022526-j9kg00qf 2585 1 Passage passage NN cord-022526-j9kg00qf 2585 2 of of IN cord-022526-j9kg00qf 2585 3 a a DT cord-022526-j9kg00qf 2585 4 nasogastric nasogastric NN cord-022526-j9kg00qf 2585 5 tube tube NN cord-022526-j9kg00qf 2585 6 is be VBZ cord-022526-j9kg00qf 2585 7 an an DT cord-022526-j9kg00qf 2585 8 effective effective JJ cord-022526-j9kg00qf 2585 9 way way NN cord-022526-j9kg00qf 2585 10 to to TO cord-022526-j9kg00qf 2585 11 detect detect VB cord-022526-j9kg00qf 2585 12 and and CC cord-022526-j9kg00qf 2585 13 localize localize VB cord-022526-j9kg00qf 2585 14 an an DT cord-022526-j9kg00qf 2585 15 obstruction obstruction NN cord-022526-j9kg00qf 2585 16 but but CC cord-022526-j9kg00qf 2585 17 provides provide VBZ cord-022526-j9kg00qf 2585 18 little little JJ cord-022526-j9kg00qf 2585 19 information information NN cord-022526-j9kg00qf 2585 20 about about IN cord-022526-j9kg00qf 2585 21 the the DT cord-022526-j9kg00qf 2585 22 nature nature NN cord-022526-j9kg00qf 2585 23 of of IN cord-022526-j9kg00qf 2585 24 the the DT cord-022526-j9kg00qf 2585 25 obstruction obstruction NN cord-022526-j9kg00qf 2585 26 or or CC cord-022526-j9kg00qf 2585 27 the the DT cord-022526-j9kg00qf 2585 28 condition condition NN cord-022526-j9kg00qf 2585 29 of of IN cord-022526-j9kg00qf 2585 30 the the DT cord-022526-j9kg00qf 2585 31 esophagus esophagus NN cord-022526-j9kg00qf 2585 32 . . . cord-022526-j9kg00qf 2586 1 The the DT cord-022526-j9kg00qf 2586 2 most most RBS cord-022526-j9kg00qf 2586 3 direct direct JJ cord-022526-j9kg00qf 2586 4 method method NN cord-022526-j9kg00qf 2586 5 for for IN cord-022526-j9kg00qf 2586 6 diagnosis diagnosis NN cord-022526-j9kg00qf 2586 7 of of IN cord-022526-j9kg00qf 2586 8 esophageal esophageal JJ cord-022526-j9kg00qf 2586 9 obstructions obstruction NNS cord-022526-j9kg00qf 2586 10 is be VBZ cord-022526-j9kg00qf 2586 11 endoscopic endoscopic JJ cord-022526-j9kg00qf 2586 12 examination examination NN cord-022526-j9kg00qf 2586 13 . . . cord-022526-j9kg00qf 2587 1 Most Most JJS cord-022526-j9kg00qf 2587 2 cases case NNS cord-022526-j9kg00qf 2587 3 of of IN cord-022526-j9kg00qf 2587 4 esophageal esophageal JJ cord-022526-j9kg00qf 2587 5 obstruction obstruction NN cord-022526-j9kg00qf 2587 6 occur occur VBP cord-022526-j9kg00qf 2587 7 at at IN cord-022526-j9kg00qf 2587 8 sites site NNS cord-022526-j9kg00qf 2587 9 of of IN cord-022526-j9kg00qf 2587 10 natural natural JJ cord-022526-j9kg00qf 2587 11 narrowing narrowing NN cord-022526-j9kg00qf 2587 12 of of IN cord-022526-j9kg00qf 2587 13 the the DT cord-022526-j9kg00qf 2587 14 esophageal esophageal JJ cord-022526-j9kg00qf 2587 15 lumen lumen NN cord-022526-j9kg00qf 2587 16 , , , cord-022526-j9kg00qf 2587 17 such such JJ cord-022526-j9kg00qf 2587 18 as as IN cord-022526-j9kg00qf 2587 19 the the DT cord-022526-j9kg00qf 2587 20 cervical cervical JJ cord-022526-j9kg00qf 2587 21 esophagus esophagus NN cord-022526-j9kg00qf 2587 22 , , , cord-022526-j9kg00qf 2587 23 the the DT cord-022526-j9kg00qf 2587 24 thoracic thoracic JJ cord-022526-j9kg00qf 2587 25 inlet inlet NN cord-022526-j9kg00qf 2587 26 , , , cord-022526-j9kg00qf 2587 27 base base NN cord-022526-j9kg00qf 2587 28 of of IN cord-022526-j9kg00qf 2587 29 the the DT cord-022526-j9kg00qf 2587 30 heart heart NN cord-022526-j9kg00qf 2587 31 , , , cord-022526-j9kg00qf 2587 32 or or CC cord-022526-j9kg00qf 2587 33 the the DT cord-022526-j9kg00qf 2587 34 terminal terminal JJ cord-022526-j9kg00qf 2587 35 esophagus esophagus NN cord-022526-j9kg00qf 2587 36 , , , cord-022526-j9kg00qf 2587 37 thus thus RB cord-022526-j9kg00qf 2587 38 one one PRP cord-022526-j9kg00qf 2587 39 may may MD cord-022526-j9kg00qf 2587 40 need need VB cord-022526-j9kg00qf 2587 41 an an DT cord-022526-j9kg00qf 2587 42 endoscope endoscope NN cord-022526-j9kg00qf 2587 43 longer long RBR cord-022526-j9kg00qf 2587 44 than than IN cord-022526-j9kg00qf 2587 45 1 1 CD cord-022526-j9kg00qf 2587 46 m m NN cord-022526-j9kg00qf 2587 47 for for IN cord-022526-j9kg00qf 2587 48 complete complete JJ cord-022526-j9kg00qf 2587 49 evaluation evaluation NN cord-022526-j9kg00qf 2587 50 . . . cord-022526-j9kg00qf 2588 1 Endoscopic endoscopic JJ cord-022526-j9kg00qf 2588 2 evaluation evaluation NN cord-022526-j9kg00qf 2588 3 is be VBZ cord-022526-j9kg00qf 2588 4 useful useful JJ cord-022526-j9kg00qf 2588 5 before before IN cord-022526-j9kg00qf 2588 6 relief relief NN cord-022526-j9kg00qf 2588 7 of of IN cord-022526-j9kg00qf 2588 8 an an DT cord-022526-j9kg00qf 2588 9 impaction impaction NN cord-022526-j9kg00qf 2588 10 to to TO cord-022526-j9kg00qf 2588 11 localize localize VB cord-022526-j9kg00qf 2588 12 the the DT cord-022526-j9kg00qf 2588 13 obstruction obstruction NN cord-022526-j9kg00qf 2588 14 and and CC cord-022526-j9kg00qf 2588 15 to to TO cord-022526-j9kg00qf 2588 16 investigate investigate VB cord-022526-j9kg00qf 2588 17 the the DT cord-022526-j9kg00qf 2588 18 nature nature NN cord-022526-j9kg00qf 2588 19 of of IN cord-022526-j9kg00qf 2588 20 the the DT cord-022526-j9kg00qf 2588 21 impaction impaction NN cord-022526-j9kg00qf 2588 22 if if IN cord-022526-j9kg00qf 2588 23 one one CD cord-022526-j9kg00qf 2588 24 suspects suspect VBZ cord-022526-j9kg00qf 2588 25 a a DT cord-022526-j9kg00qf 2588 26 foreign foreign JJ cord-022526-j9kg00qf 2588 27 body body NN cord-022526-j9kg00qf 2588 28 . . . cord-022526-j9kg00qf 2589 1 Foreign foreign JJ cord-022526-j9kg00qf 2589 2 bodies body NNS cord-022526-j9kg00qf 2589 3 may may MD cord-022526-j9kg00qf 2589 4 be be VB cord-022526-j9kg00qf 2589 5 retrievable retrievable JJ cord-022526-j9kg00qf 2589 6 via via IN cord-022526-j9kg00qf 2589 7 transendoscopic transendoscopic NNS cord-022526-j9kg00qf 2589 8 tethering tethering NN cord-022526-j9kg00qf 2589 9 . . . cord-022526-j9kg00qf 2590 1 12 12 CD cord-022526-j9kg00qf 2591 1 One one PRP cord-022526-j9kg00qf 2591 2 can can MD cord-022526-j9kg00qf 2591 3 obtain obtain VB cord-022526-j9kg00qf 2591 4 critical critical JJ cord-022526-j9kg00qf 2591 5 diagnostic diagnostic JJ cord-022526-j9kg00qf 2591 6 and and CC cord-022526-j9kg00qf 2591 7 prognostic prognostic JJ cord-022526-j9kg00qf 2591 8 information information NN cord-022526-j9kg00qf 2591 9 following follow VBG cord-022526-j9kg00qf 2591 10 resolution resolution NN cord-022526-j9kg00qf 2591 11 of of IN cord-022526-j9kg00qf 2591 12 the the DT cord-022526-j9kg00qf 2591 13 impaction impaction NN cord-022526-j9kg00qf 2591 14 . . . cord-022526-j9kg00qf 2592 1 Assessing assess VBG cord-022526-j9kg00qf 2592 2 the the DT cord-022526-j9kg00qf 2592 3 affected affect VBN cord-022526-j9kg00qf 2592 4 esophagus esophagus NN cord-022526-j9kg00qf 2592 5 for for IN cord-022526-j9kg00qf 2592 6 mucosal mucosal JJ cord-022526-j9kg00qf 2592 7 ulceration ulceration NN cord-022526-j9kg00qf 2592 8 , , , cord-022526-j9kg00qf 2592 9 rupture rupture NN cord-022526-j9kg00qf 2592 10 , , , cord-022526-j9kg00qf 2592 11 masses masse NNS cord-022526-j9kg00qf 2592 12 , , , cord-022526-j9kg00qf 2592 13 strictures stricture NNS cord-022526-j9kg00qf 2592 14 , , , cord-022526-j9kg00qf 2592 15 diverticula diverticula NN cord-022526-j9kg00qf 2592 16 , , , cord-022526-j9kg00qf 2592 17 and and CC cord-022526-j9kg00qf 2592 18 signs sign NNS cord-022526-j9kg00qf 2592 19 of of IN cord-022526-j9kg00qf 2592 20 functional functional JJ cord-022526-j9kg00qf 2592 21 abnormalities abnormality NNS cord-022526-j9kg00qf 2592 22 is be VBZ cord-022526-j9kg00qf 2592 23 important important JJ cord-022526-j9kg00qf 2592 24 ( ( -LRB- cord-022526-j9kg00qf 2592 25 Figure figure NN cord-022526-j9kg00qf 2592 26 13.9 13.9 CD cord-022526-j9kg00qf 2592 27 - - SYM cord-022526-j9kg00qf 2592 28 1 1 CD cord-022526-j9kg00qf 2592 29 ) ) -RRB- cord-022526-j9kg00qf 2592 30 . . . cord-022526-j9kg00qf 2593 1 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 2593 2 of of IN cord-022526-j9kg00qf 2593 3 the the DT cord-022526-j9kg00qf 2593 4 cervical cervical JJ cord-022526-j9kg00qf 2593 5 region region NN cord-022526-j9kg00qf 2593 6 is be VBZ cord-022526-j9kg00qf 2593 7 useful useful JJ cord-022526-j9kg00qf 2593 8 not not RB cord-022526-j9kg00qf 2593 9 only only RB cord-022526-j9kg00qf 2593 10 to to TO cord-022526-j9kg00qf 2593 11 confirm confirm VB cord-022526-j9kg00qf 2593 12 a a DT cord-022526-j9kg00qf 2593 13 cervical cervical JJ cord-022526-j9kg00qf 2593 14 esophageal esophageal JJ cord-022526-j9kg00qf 2593 15 impaction impaction NN cord-022526-j9kg00qf 2593 16 but but CC cord-022526-j9kg00qf 2593 17 also also RB cord-022526-j9kg00qf 2593 18 856 856 CD cord-022526-j9kg00qf 2593 19 PART part NN cord-022526-j9kg00qf 2593 20 II ii CD cord-022526-j9kg00qf 2593 21 Disorders disorder NNS cord-022526-j9kg00qf 2593 22 of of IN cord-022526-j9kg00qf 2593 23 Specific specific JJ cord-022526-j9kg00qf 2593 24 Body Body NNP cord-022526-j9kg00qf 2593 25 Systems Systems NNPS cord-022526-j9kg00qf 2593 26 vagal vagal JJ cord-022526-j9kg00qf 2593 27 reflex reflex NN cord-022526-j9kg00qf 2593 28 that that WDT cord-022526-j9kg00qf 2593 29 increases increase VBZ cord-022526-j9kg00qf 2593 30 lower low JJR cord-022526-j9kg00qf 2593 31 esophageal esophageal JJ cord-022526-j9kg00qf 2593 32 sphincter sphincter NN cord-022526-j9kg00qf 2593 33 tone tone NN cord-022526-j9kg00qf 2593 34 , , , cord-022526-j9kg00qf 2593 35 a a DT cord-022526-j9kg00qf 2593 36 safety safety NN cord-022526-j9kg00qf 2593 37 mechanism mechanism NN cord-022526-j9kg00qf 2593 38 against against IN cord-022526-j9kg00qf 2593 39 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2593 40 reflux reflux NN cord-022526-j9kg00qf 2593 41 . . . cord-022526-j9kg00qf 2594 1 The the DT cord-022526-j9kg00qf 2594 2 mechanical mechanical JJ cord-022526-j9kg00qf 2594 3 and and CC cord-022526-j9kg00qf 2594 4 vagal vagal JJ cord-022526-j9kg00qf 2594 5 mechanisms mechanism NNS cord-022526-j9kg00qf 2594 6 that that WDT cord-022526-j9kg00qf 2594 7 promote promote VBP cord-022526-j9kg00qf 2594 8 lower low JJR cord-022526-j9kg00qf 2594 9 esophageal esophageal JJ cord-022526-j9kg00qf 2594 10 sphincter sphincter NN cord-022526-j9kg00qf 2594 11 tone tone NN cord-022526-j9kg00qf 2594 12 prevent prevent VBP cord-022526-j9kg00qf 2594 13 spontaneous spontaneous JJ cord-022526-j9kg00qf 2594 14 decompression decompression NN cord-022526-j9kg00qf 2594 15 of of IN cord-022526-j9kg00qf 2594 16 the the DT cord-022526-j9kg00qf 2594 17 stomach stomach NN cord-022526-j9kg00qf 2594 18 , , , cord-022526-j9kg00qf 2594 19 which which WDT cord-022526-j9kg00qf 2594 20 along along IN cord-022526-j9kg00qf 2594 21 with with IN cord-022526-j9kg00qf 2594 22 a a DT cord-022526-j9kg00qf 2594 23 lack lack NN cord-022526-j9kg00qf 2594 24 of of IN cord-022526-j9kg00qf 2594 25 a a DT cord-022526-j9kg00qf 2594 26 vomiting vomiting NN cord-022526-j9kg00qf 2594 27 reflex reflex NN cord-022526-j9kg00qf 2594 28 in in IN cord-022526-j9kg00qf 2594 29 the the DT cord-022526-j9kg00qf 2594 30 horse horse NN cord-022526-j9kg00qf 2594 31 , , , cord-022526-j9kg00qf 2594 32 increases increase VBZ cord-022526-j9kg00qf 2594 33 the the DT cord-022526-j9kg00qf 2594 34 risk risk NN cord-022526-j9kg00qf 2594 35 of of IN cord-022526-j9kg00qf 2594 36 gastric gastric JJ cord-022526-j9kg00qf 2594 37 rupture rupture NN cord-022526-j9kg00qf 2594 38 during during IN cord-022526-j9kg00qf 2594 39 episodes episode NNS cord-022526-j9kg00qf 2594 40 of of IN cord-022526-j9kg00qf 2594 41 severe severe JJ cord-022526-j9kg00qf 2594 42 distention distention NN cord-022526-j9kg00qf 2594 43 . . . cord-022526-j9kg00qf 2595 1 Esophageal esophageal JJ cord-022526-j9kg00qf 2595 2 obstruction obstruction NN cord-022526-j9kg00qf 2595 3 has have VBZ cord-022526-j9kg00qf 2595 4 many many JJ cord-022526-j9kg00qf 2595 5 causes cause NNS cord-022526-j9kg00qf 2595 6 ( ( -LRB- cord-022526-j9kg00qf 2595 7 Table table NN cord-022526-j9kg00qf 2595 8 13 13 CD cord-022526-j9kg00qf 2595 9 .9 .9 CD cord-022526-j9kg00qf 2595 10 - - SYM cord-022526-j9kg00qf 2595 11 1 1 CD cord-022526-j9kg00qf 2595 12 ) ) -RRB- cord-022526-j9kg00qf 2596 1 and and CC cord-022526-j9kg00qf 2596 2 most most RBS cord-022526-j9kg00qf 2596 3 often often RB cord-022526-j9kg00qf 2596 4 is be VBZ cord-022526-j9kg00qf 2596 5 manifested manifest VBN cord-022526-j9kg00qf 2596 6 clinically clinically RB cord-022526-j9kg00qf 2596 7 by by IN cord-022526-j9kg00qf 2596 8 impaction impaction NN cord-022526-j9kg00qf 2596 9 of of IN cord-022526-j9kg00qf 2596 10 food food NN cord-022526-j9kg00qf 2596 11 material material NN cord-022526-j9kg00qf 2596 12 and and CC cord-022526-j9kg00qf 2596 13 resulting result VBG cord-022526-j9kg00qf 2596 14 esophageal esophageal JJ cord-022526-j9kg00qf 2596 15 dysphagia dysphagia NN cord-022526-j9kg00qf 2596 16 . . . cord-022526-j9kg00qf 2597 1 Esophageal esophageal JJ cord-022526-j9kg00qf 2597 2 obstruction obstruction NN cord-022526-j9kg00qf 2597 3 may may MD cord-022526-j9kg00qf 2597 4 be be VB cord-022526-j9kg00qf 2597 5 caused cause VBN cord-022526-j9kg00qf 2597 6 by by IN cord-022526-j9kg00qf 2597 7 primary primary JJ cord-022526-j9kg00qf 2597 8 impactions impaction NNS cord-022526-j9kg00qf 2597 9 ( ( -LRB- cord-022526-j9kg00qf 2597 10 simple simple JJ cord-022526-j9kg00qf 2597 11 choke choke NN cord-022526-j9kg00qf 2597 12 ) ) -RRB- cord-022526-j9kg00qf 2597 13 of of IN cord-022526-j9kg00qf 2597 14 roughage roughage NN cord-022526-j9kg00qf 2597 15 , , , cord-022526-j9kg00qf 2597 16 particularly particularly RB cord-022526-j9kg00qf 2597 17 leafy leafy JJ cord-022526-j9kg00qf 2597 18 alfalfa alfalfa NN cord-022526-j9kg00qf 2597 19 hay hay NN cord-022526-j9kg00qf 2597 20 , , , cord-022526-j9kg00qf 2597 21 coarse coarse JJ cord-022526-j9kg00qf 2597 22 grass grass NN cord-022526-j9kg00qf 2597 23 hay hay NN cord-022526-j9kg00qf 2597 24 , , , cord-022526-j9kg00qf 2597 25 bedding bedding NN cord-022526-j9kg00qf 2597 26 , , , cord-022526-j9kg00qf 2597 27 and and CC cord-022526-j9kg00qf 2597 28 even even RB cord-022526-j9kg00qf 2597 29 grass grass NN cord-022526-j9kg00qf 2597 30 . . . cord-022526-j9kg00qf 2598 1 Prior prior JJ cord-022526-j9kg00qf 2598 2 esophageal esophageal JJ cord-022526-j9kg00qf 2598 3 trauma trauma NN cord-022526-j9kg00qf 2598 4 or or CC cord-022526-j9kg00qf 2598 5 poor poor JJ cord-022526-j9kg00qf 2598 6 mastication mastication NN cord-022526-j9kg00qf 2598 7 caused cause VBN cord-022526-j9kg00qf 2598 8 by by IN cord-022526-j9kg00qf 2598 9 dental dental JJ cord-022526-j9kg00qf 2598 10 abnormalities abnormality NNS cord-022526-j9kg00qf 2598 11 may may MD cord-022526-j9kg00qf 2598 12 predispose predispose VB cord-022526-j9kg00qf 2598 13 horses horse NNS cord-022526-j9kg00qf 2598 14 to to IN cord-022526-j9kg00qf 2598 15 primary primary JJ cord-022526-j9kg00qf 2598 16 esophageal esophageal JJ cord-022526-j9kg00qf 2598 17 impaction impaction NN cord-022526-j9kg00qf 2598 18 . . . cord-022526-j9kg00qf 2599 1 3 3 LS cord-022526-j9kg00qf 2600 1 Wolfing wolf VBG cord-022526-j9kg00qf 2600 2 or or CC cord-022526-j9kg00qf 2600 3 gulping gulp VBG cord-022526-j9kg00qf 2600 4 food food NN cord-022526-j9kg00qf 2600 5 may may MD cord-022526-j9kg00qf 2600 6 precipitate precipitate VB cord-022526-j9kg00qf 2600 7 primary primary JJ cord-022526-j9kg00qf 2600 8 impactions impaction NNS cord-022526-j9kg00qf 2600 9 , , , cord-022526-j9kg00qf 2600 10 particularly particularly RB cord-022526-j9kg00qf 2600 11 if if IN cord-022526-j9kg00qf 2600 12 the the DT cord-022526-j9kg00qf 2600 13 horse horse NN cord-022526-j9kg00qf 2600 14 is be VBZ cord-022526-j9kg00qf 2600 15 exhausted exhaust VBN cord-022526-j9kg00qf 2600 16 or or CC cord-022526-j9kg00qf 2600 17 mildly mildly RB cord-022526-j9kg00qf 2600 18 dehydrated dehydrated JJ cord-022526-j9kg00qf 2600 19 after after IN cord-022526-j9kg00qf 2600 20 a a DT cord-022526-j9kg00qf 2600 21 long long JJ cord-022526-j9kg00qf 2600 22 ride ride NN cord-022526-j9kg00qf 2600 23 or or CC cord-022526-j9kg00qf 2600 24 is be VBZ cord-022526-j9kg00qf 2600 25 weakened weaken VBN cord-022526-j9kg00qf 2600 26 from from IN cord-022526-j9kg00qf 2600 27 chronic chronic JJ cord-022526-j9kg00qf 2600 28 debilitation debilitation NN cord-022526-j9kg00qf 2600 29 . . . cord-022526-j9kg00qf 2601 1 Impactions impaction NNS cord-022526-j9kg00qf 2601 2 also also RB cord-022526-j9kg00qf 2601 3 may may MD cord-022526-j9kg00qf 2601 4 result result VB cord-022526-j9kg00qf 2601 5 from from IN cord-022526-j9kg00qf 2601 6 disorders disorder NNS cord-022526-j9kg00qf 2601 7 that that WDT cord-022526-j9kg00qf 2601 8 physically physically RB cord-022526-j9kg00qf 2601 9 impede impede VBP cord-022526-j9kg00qf 2601 10 the the DT cord-022526-j9kg00qf 2601 11 passage passage NN cord-022526-j9kg00qf 2601 12 of of IN cord-022526-j9kg00qf 2601 13 food food NN cord-022526-j9kg00qf 2601 14 material material NN cord-022526-j9kg00qf 2601 15 and and CC cord-022526-j9kg00qf 2601 16 fluid fluid NN cord-022526-j9kg00qf 2601 17 by by IN cord-022526-j9kg00qf 2601 18 narrowing narrow VBG cord-022526-j9kg00qf 2601 19 the the DT cord-022526-j9kg00qf 2601 20 luminal luminal JJ cord-022526-j9kg00qf 2601 21 diameter diameter NN cord-022526-j9kg00qf 2601 22 , , , cord-022526-j9kg00qf 2601 23 reduce reduce VB cord-022526-j9kg00qf 2601 24 the the DT cord-022526-j9kg00qf 2601 25 compliance compliance NN cord-022526-j9kg00qf 2601 26 of of IN cord-022526-j9kg00qf 2601 27 the the DT cord-022526-j9kg00qf 2601 28 esophageal esophageal JJ cord-022526-j9kg00qf 2601 29 wall wall NN cord-022526-j9kg00qf 2601 30 , , , cord-022526-j9kg00qf 2601 31 or or CC cord-022526-j9kg00qf 2601 32 alter alter VB cord-022526-j9kg00qf 2601 33 the the DT cord-022526-j9kg00qf 2601 34 conformation conformation NN cord-022526-j9kg00qf 2601 35 of of IN cord-022526-j9kg00qf 2601 36 the the DT cord-022526-j9kg00qf 2601 37 esophageal esophageal JJ cord-022526-j9kg00qf 2601 38 wall wall NN cord-022526-j9kg00qf 2601 39 such such JJ cord-022526-j9kg00qf 2601 40 that that IN cord-022526-j9kg00qf 2601 41 food food NN cord-022526-j9kg00qf 2601 42 material material NN cord-022526-j9kg00qf 2601 43 accumulates accumulate VBZ cord-022526-j9kg00qf 2601 44 in in IN cord-022526-j9kg00qf 2601 45 a a DT cord-022526-j9kg00qf 2601 46 pocket pocket NN cord-022526-j9kg00qf 2601 47 or or CC cord-022526-j9kg00qf 2601 48 diverticulum diverticulum NN cord-022526-j9kg00qf 2601 49 . . . cord-022526-j9kg00qf 2602 1 Foreign foreign JJ cord-022526-j9kg00qf 2602 2 bodies body NNS cord-022526-j9kg00qf 2602 3 , , , cord-022526-j9kg00qf 2602 4 intra intra JJ cord-022526-j9kg00qf 2602 5 - - JJ cord-022526-j9kg00qf 2602 6 or or CC cord-022526-j9kg00qf 2602 7 extramural extramural JJ cord-022526-j9kg00qf 2602 8 masses masse NNS cord-022526-j9kg00qf 2602 9 , , , cord-022526-j9kg00qf 2602 10 or or CC cord-022526-j9kg00qf 2602 11 acquired acquire VBN cord-022526-j9kg00qf 2602 12 or or CC cord-022526-j9kg00qf 2602 13 congenital congenital JJ cord-022526-j9kg00qf 2602 14 anomalies anomaly NNS cord-022526-j9kg00qf 2602 15 cause cause VBP cord-022526-j9kg00qf 2602 16 these these DT cord-022526-j9kg00qf 2602 17 so so RB cord-022526-j9kg00qf 2602 18 - - HYPH cord-022526-j9kg00qf 2602 19 called call VBN cord-022526-j9kg00qf 2602 20 secondary secondary JJ cord-022526-j9kg00qf 2602 21 to to TO cord-022526-j9kg00qf 2602 22 provide provide VB cord-022526-j9kg00qf 2602 23 critical critical JJ cord-022526-j9kg00qf 2602 24 information information NN cord-022526-j9kg00qf 2602 25 about about IN cord-022526-j9kg00qf 2602 26 the the DT cord-022526-j9kg00qf 2602 27 location location NN cord-022526-j9kg00qf 2602 28 and and CC cord-022526-j9kg00qf 2602 29 extent extent NN cord-022526-j9kg00qf 2602 30 of of IN cord-022526-j9kg00qf 2602 31 the the DT cord-022526-j9kg00qf 2602 32 impaction impaction NN cord-022526-j9kg00qf 2602 33 and and CC cord-022526-j9kg00qf 2602 34 esophageal esophageal JJ cord-022526-j9kg00qf 2602 35 wall wall NN cord-022526-j9kg00qf 2602 36 thickness thickness NN cord-022526-j9kg00qf 2602 37 and and CC cord-022526-j9kg00qf 2602 38 integrity integrity NN cord-022526-j9kg00qf 2602 39 . . . cord-022526-j9kg00qf 2603 1 Ultrasonography Ultrasonography NNP cord-022526-j9kg00qf 2603 2 may may MD cord-022526-j9kg00qf 2603 3 provide provide VB cord-022526-j9kg00qf 2603 4 information information NN cord-022526-j9kg00qf 2603 5 about about IN cord-022526-j9kg00qf 2603 6 the the DT cord-022526-j9kg00qf 2603 7 cause cause NN cord-022526-j9kg00qf 2603 8 . . . cord-022526-j9kg00qf 2604 1 13 13 CD cord-022526-j9kg00qf 2604 2 Radiographic radiographic JJ cord-022526-j9kg00qf 2604 3 assessment assessment NN cord-022526-j9kg00qf 2604 4 of of IN cord-022526-j9kg00qf 2604 5 the the DT cord-022526-j9kg00qf 2604 6 esophagus esophagus NN cord-022526-j9kg00qf 2604 7 can can MD cord-022526-j9kg00qf 2604 8 confirm confirm VB cord-022526-j9kg00qf 2604 9 the the DT cord-022526-j9kg00qf 2604 10 presence presence NN cord-022526-j9kg00qf 2604 11 of of IN cord-022526-j9kg00qf 2604 12 esophageal esophageal JJ cord-022526-j9kg00qf 2604 13 obstruction obstruction NN cord-022526-j9kg00qf 2604 14 in in IN cord-022526-j9kg00qf 2604 15 cases case NNS cord-022526-j9kg00qf 2604 16 in in IN cord-022526-j9kg00qf 2604 17 which which WDT cord-022526-j9kg00qf 2604 18 one one PRP cord-022526-j9kg00qf 2604 19 can can MD cord-022526-j9kg00qf 2604 20 not not RB cord-022526-j9kg00qf 2604 21 view view VB cord-022526-j9kg00qf 2604 22 the the DT cord-022526-j9kg00qf 2604 23 affected affected JJ cord-022526-j9kg00qf 2604 24 area area NN cord-022526-j9kg00qf 2604 25 adequately adequately RB cord-022526-j9kg00qf 2604 26 using use VBG cord-022526-j9kg00qf 2604 27 endoscopy endoscopy NN cord-022526-j9kg00qf 2604 28 . . . cord-022526-j9kg00qf 2605 1 One one PRP cord-022526-j9kg00qf 2605 2 can can MD cord-022526-j9kg00qf 2605 3 detect detect VB cord-022526-j9kg00qf 2605 4 impacted impact VBN cord-022526-j9kg00qf 2605 5 food food NN cord-022526-j9kg00qf 2605 6 material material NN cord-022526-j9kg00qf 2605 7 in in IN cord-022526-j9kg00qf 2605 8 the the DT cord-022526-j9kg00qf 2605 9 esophagus esophagus NN cord-022526-j9kg00qf 2605 10 by by IN cord-022526-j9kg00qf 2605 11 a a DT cord-022526-j9kg00qf 2605 12 typical typical JJ cord-022526-j9kg00qf 2605 13 granular granular JJ cord-022526-j9kg00qf 2605 14 pattern pattern NN cord-022526-j9kg00qf 2605 15 and and CC cord-022526-j9kg00qf 2605 16 often often RB cord-022526-j9kg00qf 2605 17 can can MD cord-022526-j9kg00qf 2605 18 observe observe VB cord-022526-j9kg00qf 2605 19 gas gas NN cord-022526-j9kg00qf 2605 20 accumulation accumulation NN cord-022526-j9kg00qf 2605 21 proximal proximal JJ cord-022526-j9kg00qf 2605 22 to to IN cord-022526-j9kg00qf 2605 23 the the DT cord-022526-j9kg00qf 2605 24 obstruction obstruction NN cord-022526-j9kg00qf 2605 25 . . . cord-022526-j9kg00qf 2606 1 Air air NN cord-022526-j9kg00qf 2606 2 or or CC cord-022526-j9kg00qf 2606 3 barium barium NN cord-022526-j9kg00qf 2606 4 contrast contrast NN cord-022526-j9kg00qf 2606 5 radiographic radiographic JJ cord-022526-j9kg00qf 2606 6 studies study NNS cord-022526-j9kg00qf 2606 7 are be VBP cord-022526-j9kg00qf 2606 8 most most RBS cord-022526-j9kg00qf 2606 9 useful useful JJ cord-022526-j9kg00qf 2606 10 for for IN cord-022526-j9kg00qf 2606 11 evaluating evaluate VBG cord-022526-j9kg00qf 2606 12 the the DT cord-022526-j9kg00qf 2606 13 esophagus esophagus NN cord-022526-j9kg00qf 2606 14 following follow VBG cord-022526-j9kg00qf 2606 15 relief relief NN cord-022526-j9kg00qf 2606 16 of of IN cord-022526-j9kg00qf 2606 17 the the DT cord-022526-j9kg00qf 2606 18 impaction impaction NN cord-022526-j9kg00qf 2606 19 if if IN cord-022526-j9kg00qf 2606 20 one one CD cord-022526-j9kg00qf 2606 21 suspects suspect VBZ cord-022526-j9kg00qf 2606 22 a a DT cord-022526-j9kg00qf 2606 23 stricture stricture NN cord-022526-j9kg00qf 2606 24 . . . cord-022526-j9kg00qf 2607 1 One one CD cord-022526-j9kg00qf 2607 2 often often RB cord-022526-j9kg00qf 2607 3 can can MD cord-022526-j9kg00qf 2607 4 detect detect VB cord-022526-j9kg00qf 2607 5 esophageal esophageal JJ cord-022526-j9kg00qf 2607 6 dilation dilation NN cord-022526-j9kg00qf 2607 7 , , , cord-022526-j9kg00qf 2607 8 diverticula diverticula NN cord-022526-j9kg00qf 2607 9 , , , cord-022526-j9kg00qf 2607 10 rupture rupture NN cord-022526-j9kg00qf 2607 11 , , , cord-022526-j9kg00qf 2607 12 functional functional JJ cord-022526-j9kg00qf 2607 13 disorder disorder NN cord-022526-j9kg00qf 2607 14 ( ( -LRB- cord-022526-j9kg00qf 2607 15 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2607 16 ) ) -RRB- cord-022526-j9kg00qf 2607 17 , , , cord-022526-j9kg00qf 2607 18 or or CC cord-022526-j9kg00qf 2607 19 luminal luminal JJ cord-022526-j9kg00qf 2607 20 narrowing narrowing NN cord-022526-j9kg00qf 2607 21 caused cause VBN cord-022526-j9kg00qf 2607 22 by by IN cord-022526-j9kg00qf 2607 23 extraluminal extraluminal JJ cord-022526-j9kg00qf 2607 24 compression compression NN cord-022526-j9kg00qf 2607 25 more more RBR cord-022526-j9kg00qf 2607 26 easily easily RB cord-022526-j9kg00qf 2607 27 using use VBG cord-022526-j9kg00qf 2607 28 contrast contrast NN cord-022526-j9kg00qf 2607 29 radiographic radiographic JJ cord-022526-j9kg00qf 2607 30 studies study NNS cord-022526-j9kg00qf 2607 31 instead instead RB cord-022526-j9kg00qf 2607 32 of of IN cord-022526-j9kg00qf 2607 33 endoscopy endoscopy NN cord-022526-j9kg00qf 2607 34 ( ( -LRB- cord-022526-j9kg00qf 2607 35 Figure figure NN cord-022526-j9kg00qf 2607 36 13 13 CD cord-022526-j9kg00qf 2607 37 .9 .9 CD cord-022526-j9kg00qf 2607 38 - - SYM cord-022526-j9kg00qf 2607 39 2 2 CD cord-022526-j9kg00qf 2607 40 ) ) -RRB- cord-022526-j9kg00qf 2607 41 . . . cord-022526-j9kg00qf 2608 1 14 14 CD cord-022526-j9kg00qf 2608 2 - - SYM cord-022526-j9kg00qf 2608 3 16 16 CD cord-022526-j9kg00qf 2608 4 One one PRP cord-022526-j9kg00qf 2608 5 should should MD cord-022526-j9kg00qf 2608 6 take take VB cord-022526-j9kg00qf 2608 7 care care NN cord-022526-j9kg00qf 2608 8 when when WRB cord-022526-j9kg00qf 2608 9 interpreting interpret VBG cord-022526-j9kg00qf 2608 10 radiographic radiographic JJ cord-022526-j9kg00qf 2608 11 studies study NNS cord-022526-j9kg00qf 2608 12 in in IN cord-022526-j9kg00qf 2608 13 sedated sedated JJ cord-022526-j9kg00qf 2608 14 horses horse NNS cord-022526-j9kg00qf 2608 15 , , , cord-022526-j9kg00qf 2608 16 particularly particularly RB cord-022526-j9kg00qf 2608 17 after after IN cord-022526-j9kg00qf 2608 18 passage passage NN cord-022526-j9kg00qf 2608 19 of of IN cord-022526-j9kg00qf 2608 20 a a DT cord-022526-j9kg00qf 2608 21 nasogastric nasogastric NN cord-022526-j9kg00qf 2608 22 tube tube NN cord-022526-j9kg00qf 2608 23 or or CC cord-022526-j9kg00qf 2608 24 other other JJ cord-022526-j9kg00qf 2608 25 esophageal esophageal JJ cord-022526-j9kg00qf 2608 26 manipulations manipulation NNS cord-022526-j9kg00qf 2608 27 that that WDT cord-022526-j9kg00qf 2608 28 may may MD cord-022526-j9kg00qf 2608 29 contribute contribute VB cord-022526-j9kg00qf 2608 30 to to IN cord-022526-j9kg00qf 2608 31 esophageal esophageal JJ cord-022526-j9kg00qf 2608 32 dilation dilation NN cord-022526-j9kg00qf 2608 33 . . . cord-022526-j9kg00qf 2609 1 17 17 CD cord-022526-j9kg00qf 2610 1 The the DT cord-022526-j9kg00qf 2610 2 primary primary JJ cord-022526-j9kg00qf 2610 3 goal goal NN cord-022526-j9kg00qf 2610 4 of of IN cord-022526-j9kg00qf 2610 5 treatment treatment NN cord-022526-j9kg00qf 2610 6 for for IN cord-022526-j9kg00qf 2610 7 esophageal esophageal JJ cord-022526-j9kg00qf 2610 8 impaction impaction NN cord-022526-j9kg00qf 2610 9 is be VBZ cord-022526-j9kg00qf 2610 10 to to TO cord-022526-j9kg00qf 2610 11 relieve relieve VB cord-022526-j9kg00qf 2610 12 the the DT cord-022526-j9kg00qf 2610 13 obstruction obstruction NN cord-022526-j9kg00qf 2610 14 . . . cord-022526-j9kg00qf 2611 1 Parenteral Parenteral NNP cord-022526-j9kg00qf 2611 2 administration administration NN cord-022526-j9kg00qf 2611 3 of of IN cord-022526-j9kg00qf 2611 4 acepromazine acepromazine NNP cord-022526-j9kg00qf 2611 5 ( ( -LRB- cord-022526-j9kg00qf 2611 6 0.05 0.05 CD cord-022526-j9kg00qf 2611 7 mg mg NNP cord-022526-j9kg00qf 2611 8 / / SYM cord-022526-j9kg00qf 2611 9 kg kg NNP cord-022526-j9kg00qf 2611 10 intravenously intravenously RB cord-022526-j9kg00qf 2611 11 ) ) -RRB- cord-022526-j9kg00qf 2611 12 , , , cord-022526-j9kg00qf 2611 13 xylazine xylazine NNP cord-022526-j9kg00qf 2611 14 ( ( -LRB- cord-022526-j9kg00qf 2612 1 0.25 0.25 CD cord-022526-j9kg00qf 2612 2 to to IN cord-022526-j9kg00qf 2612 3 0.5 0.5 CD cord-022526-j9kg00qf 2612 4 mg mg NNP cord-022526-j9kg00qf 2612 5 / / SYM cord-022526-j9kg00qf 2612 6 kg kg NNP cord-022526-j9kg00qf 2612 7 intravenously intravenously RB cord-022526-j9kg00qf 2612 8 ) ) -RRB- cord-022526-j9kg00qf 2612 9 or or CC cord-022526-j9kg00qf 2612 10 detomidine detomidine NN cord-022526-j9kg00qf 2612 11 ( ( -LRB- cord-022526-j9kg00qf 2612 12 0.01 0.01 CD cord-022526-j9kg00qf 2612 13 to to IN cord-022526-j9kg00qf 2612 14 0.02 0.02 CD cord-022526-j9kg00qf 2612 15 mg mg NNP cord-022526-j9kg00qf 2612 16 / / SYM cord-022526-j9kg00qf 2612 17 kg kg NNP cord-022526-j9kg00qf 2612 18 intravenously intravenously RB cord-022526-j9kg00qf 2612 19 ) ) -RRB- cord-022526-j9kg00qf 2612 20 , , , cord-022526-j9kg00qf 2612 21 oxytocin oxytocin NNS cord-022526-j9kg00qf 2612 22 ( ( -LRB- cord-022526-j9kg00qf 2612 23 0.11 0.11 CD cord-022526-j9kg00qf 2612 24 to to IN cord-022526-j9kg00qf 2612 25 0.22 0.22 CD cord-022526-j9kg00qf 2612 26 IU IU NNP cord-022526-j9kg00qf 2612 27 / / SYM cord-022526-j9kg00qf 2612 28 kg kg NNS cord-022526-j9kg00qf 2612 29 intramuscularly intramuscularly RB cord-022526-j9kg00qf 2612 30 ) ) -RRB- cord-022526-j9kg00qf 2612 31 , , . cord-022526-j9kg00qf 2613 1 and/or and/or CC cord-022526-j9kg00qf 2613 2 esophageal esophageal JJ cord-022526-j9kg00qf 2613 3 instillation instillation NN cord-022526-j9kg00qf 2613 4 of of IN cord-022526-j9kg00qf 2613 5 lidocaine lidocaine NN cord-022526-j9kg00qf 2613 6 ( ( -LRB- cord-022526-j9kg00qf 2613 7 30 30 CD cord-022526-j9kg00qf 2613 8 to to TO cord-022526-j9kg00qf 2613 9 60 60 CD cord-022526-j9kg00qf 2613 10 ml ml NNS cord-022526-j9kg00qf 2613 11 of of IN cord-022526-j9kg00qf 2613 12 1 1 CD cord-022526-j9kg00qf 2613 13 % % NN cord-022526-j9kg00qf 2613 14 lidocaine lidocaine NN cord-022526-j9kg00qf 2613 15 ) ) -RRB- cord-022526-j9kg00qf 2613 16 may may MD cord-022526-j9kg00qf 2613 17 reduce reduce VB cord-022526-j9kg00qf 2613 18 esophageal esophageal JJ cord-022526-j9kg00qf 2613 19 spasms spasm NNS cord-022526-j9kg00qf 2613 20 caused cause VBN cord-022526-j9kg00qf 2613 21 by by IN cord-022526-j9kg00qf 2613 22 pain pain NN cord-022526-j9kg00qf 2613 23 or or CC cord-022526-j9kg00qf 2613 24 may may MD cord-022526-j9kg00qf 2613 25 decrease decrease VB cord-022526-j9kg00qf 2613 26 esophageal esophageal JJ cord-022526-j9kg00qf 2613 27 tone tone NN cord-022526-j9kg00qf 2613 28 . . . cord-022526-j9kg00qf 2614 1 [ [ -LRB- cord-022526-j9kg00qf 2614 2 17 17 CD cord-022526-j9kg00qf 2614 3 ] ] -RRB- cord-022526-j9kg00qf 2614 4 [ [ -LRB- cord-022526-j9kg00qf 2614 5 18 18 CD cord-022526-j9kg00qf 2614 6 ] ] -RRB- cord-022526-j9kg00qf 2614 7 [ [ -LRB- cord-022526-j9kg00qf 2614 8 19 19 CD cord-022526-j9kg00qf 2614 9 ] ] -RRB- cord-022526-j9kg00qf 2615 1 [ [ -LRB- cord-022526-j9kg00qf 2615 2 20 20 CD cord-022526-j9kg00qf 2615 3 ] ] -RRB- cord-022526-j9kg00qf 2616 1 Some some DT cord-022526-j9kg00qf 2616 2 clinicians clinician NNS cord-022526-j9kg00qf 2616 3 advocate advocate VBP cord-022526-j9kg00qf 2616 4 parasympatholytic parasympatholytic JJ cord-022526-j9kg00qf 2616 5 drugs drug NNS cord-022526-j9kg00qf 2616 6 such such JJ cord-022526-j9kg00qf 2616 7 as as IN cord-022526-j9kg00qf 2616 8 atropine atropine NN cord-022526-j9kg00qf 2616 9 ( ( -LRB- cord-022526-j9kg00qf 2616 10 0.02 0.02 CD cord-022526-j9kg00qf 2616 11 mg mg NNP cord-022526-j9kg00qf 2616 12 / / SYM cord-022526-j9kg00qf 2616 13 kg kg NNP cord-022526-j9kg00qf 2616 14 intravenously intravenously RB cord-022526-j9kg00qf 2616 15 ) ) -RRB- cord-022526-j9kg00qf 2616 16 to to TO cord-022526-j9kg00qf 2616 17 reduce reduce VB cord-022526-j9kg00qf 2616 18 salivary salivary NN cord-022526-j9kg00qf 2616 19 secretions secretion NNS cord-022526-j9kg00qf 2616 20 and and CC cord-022526-j9kg00qf 2616 21 lessen lessen VB cord-022526-j9kg00qf 2616 22 the the DT cord-022526-j9kg00qf 2616 23 risk risk NN cord-022526-j9kg00qf 2616 24 of of IN cord-022526-j9kg00qf 2616 25 aspiration aspiration NN cord-022526-j9kg00qf 2616 26 . . . cord-022526-j9kg00qf 2617 1 However however RB cord-022526-j9kg00qf 2617 2 , , , cord-022526-j9kg00qf 2617 3 undesirable undesirable JJ cord-022526-j9kg00qf 2617 4 effects effect NNS cord-022526-j9kg00qf 2617 5 of of IN cord-022526-j9kg00qf 2617 6 atropine atropine NN cord-022526-j9kg00qf 2617 7 including include VBG cord-022526-j9kg00qf 2617 8 excessive excessive JJ cord-022526-j9kg00qf 2617 9 drying drying NN cord-022526-j9kg00qf 2617 10 of of IN cord-022526-j9kg00qf 2617 11 the the DT cord-022526-j9kg00qf 2617 12 impaction impaction NN cord-022526-j9kg00qf 2617 13 and and CC cord-022526-j9kg00qf 2617 14 inhibition inhibition NN cord-022526-j9kg00qf 2617 15 of of IN cord-022526-j9kg00qf 2617 16 distal distal JJ cord-022526-j9kg00qf 2617 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2617 18 motility motility NN cord-022526-j9kg00qf 2617 19 may may MD cord-022526-j9kg00qf 2617 20 preclude preclude VB cord-022526-j9kg00qf 2617 21 its -PRON- PRP$ cord-022526-j9kg00qf 2617 22 use use NN cord-022526-j9kg00qf 2617 23 . . . cord-022526-j9kg00qf 2618 1 Resolution resolution NN cord-022526-j9kg00qf 2618 2 of of IN cord-022526-j9kg00qf 2618 3 an an DT cord-022526-j9kg00qf 2618 4 impaction impaction NN cord-022526-j9kg00qf 2618 5 may may MD cord-022526-j9kg00qf 2618 6 require require VB cord-022526-j9kg00qf 2618 7 physical physical JJ cord-022526-j9kg00qf 2618 8 dispersal dispersal NN cord-022526-j9kg00qf 2618 9 of of IN cord-022526-j9kg00qf 2618 10 the the DT cord-022526-j9kg00qf 2618 11 material material NN cord-022526-j9kg00qf 2618 12 . . . cord-022526-j9kg00qf 2619 1 18 18 CD cord-022526-j9kg00qf 2620 1 One one PRP cord-022526-j9kg00qf 2620 2 can can MD cord-022526-j9kg00qf 2620 3 use use VB cord-022526-j9kg00qf 2620 4 a a DT cord-022526-j9kg00qf 2620 5 nasogastric nasogastric NN cord-022526-j9kg00qf 2620 6 tube tube NN cord-022526-j9kg00qf 2620 7 to to TO cord-022526-j9kg00qf 2620 8 displace displace VB cord-022526-j9kg00qf 2620 9 the the DT cord-022526-j9kg00qf 2620 10 impacted impact VBN cord-022526-j9kg00qf 2620 11 material material NN cord-022526-j9kg00qf 2620 12 along along IN cord-022526-j9kg00qf 2620 13 with with IN cord-022526-j9kg00qf 2620 14 external external JJ cord-022526-j9kg00qf 2620 15 massage massage NN cord-022526-j9kg00qf 2620 16 if if IN cord-022526-j9kg00qf 2620 17 the the DT cord-022526-j9kg00qf 2620 18 obstruction obstruction NN cord-022526-j9kg00qf 2620 19 is be VBZ cord-022526-j9kg00qf 2620 20 in in IN cord-022526-j9kg00qf 2620 21 the the DT cord-022526-j9kg00qf 2620 22 cervical cervical JJ cord-022526-j9kg00qf 2620 23 region region NN cord-022526-j9kg00qf 2620 24 . . . cord-022526-j9kg00qf 2621 1 Often often RB cord-022526-j9kg00qf 2621 2 , , , cord-022526-j9kg00qf 2621 3 carefully carefully RB cord-022526-j9kg00qf 2621 4 lavaging lavage VBG cord-022526-j9kg00qf 2621 5 the the DT cord-022526-j9kg00qf 2621 6 esophagus esophagus NN cord-022526-j9kg00qf 2621 7 with with IN cord-022526-j9kg00qf 2621 8 water water NN cord-022526-j9kg00qf 2621 9 via via IN cord-022526-j9kg00qf 2621 10 an an DT cord-022526-j9kg00qf 2621 11 uncuffed uncuffed NNS cord-022526-j9kg00qf 2621 12 or or CC cord-022526-j9kg00qf 2621 13 a a DT cord-022526-j9kg00qf 2621 14 cuffed cuffed JJ cord-022526-j9kg00qf 2621 15 nasogastric nasogastric NN cord-022526-j9kg00qf 2621 16 tube tube NN cord-022526-j9kg00qf 2621 17 while while IN cord-022526-j9kg00qf 2621 18 the the DT cord-022526-j9kg00qf 2621 19 head head NN cord-022526-j9kg00qf 2621 20 is be VBZ cord-022526-j9kg00qf 2621 21 lowered lower VBN cord-022526-j9kg00qf 2621 22 is be VBZ cord-022526-j9kg00qf 2621 23 necessary necessary JJ cord-022526-j9kg00qf 2621 24 to to TO cord-022526-j9kg00qf 2621 25 aid aid VB cord-022526-j9kg00qf 2621 26 in in IN cord-022526-j9kg00qf 2621 27 breaking break VBG cord-022526-j9kg00qf 2621 28 up up RP cord-022526-j9kg00qf 2621 29 the the DT cord-022526-j9kg00qf 2621 30 impaction impaction NN cord-022526-j9kg00qf 2621 31 . . . cord-022526-j9kg00qf 2622 1 Some some DT cord-022526-j9kg00qf 2622 2 clinicians clinician NNS cord-022526-j9kg00qf 2622 3 advocate advocate VBP cord-022526-j9kg00qf 2622 4 a a DT cord-022526-j9kg00qf 2622 5 dual dual JJ cord-022526-j9kg00qf 2622 6 tube tube NN cord-022526-j9kg00qf 2622 7 method method NN cord-022526-j9kg00qf 2622 8 whereby whereby WRB cord-022526-j9kg00qf 2622 9 a a DT cord-022526-j9kg00qf 2622 10 tube tube NN cord-022526-j9kg00qf 2622 11 is be VBZ cord-022526-j9kg00qf 2622 12 placed place VBN cord-022526-j9kg00qf 2622 13 through through IN cord-022526-j9kg00qf 2622 14 each each DT cord-022526-j9kg00qf 2622 15 nasal nasal NN cord-022526-j9kg00qf 2622 16 passage passage NN cord-022526-j9kg00qf 2622 17 into into IN cord-022526-j9kg00qf 2622 18 the the DT cord-022526-j9kg00qf 2622 19 esophagus esophagus NN cord-022526-j9kg00qf 2622 20 for for IN cord-022526-j9kg00qf 2622 21 ingress ingress NN cord-022526-j9kg00qf 2622 22 and and CC cord-022526-j9kg00qf 2622 23 egress egress NN cord-022526-j9kg00qf 2622 24 of of IN cord-022526-j9kg00qf 2622 25 the the DT cord-022526-j9kg00qf 2622 26 lavage lavage NN cord-022526-j9kg00qf 2622 27 fluid fluid NN cord-022526-j9kg00qf 2622 28 . . . cord-022526-j9kg00qf 2623 1 Because because IN cord-022526-j9kg00qf 2623 2 of of IN cord-022526-j9kg00qf 2623 3 the the DT cord-022526-j9kg00qf 2623 4 risk risk NN cord-022526-j9kg00qf 2623 5 of of IN cord-022526-j9kg00qf 2623 6 aspiration aspiration NN cord-022526-j9kg00qf 2623 7 of of IN cord-022526-j9kg00qf 2623 8 water water NN cord-022526-j9kg00qf 2623 9 and and CC cord-022526-j9kg00qf 2623 10 food food NN cord-022526-j9kg00qf 2623 11 material material NN cord-022526-j9kg00qf 2623 12 , , , cord-022526-j9kg00qf 2623 13 esophageal esophageal JJ cord-022526-j9kg00qf 2623 14 lavage lavage NN cord-022526-j9kg00qf 2623 15 sometimes sometimes RB cord-022526-j9kg00qf 2623 16 is be VBZ cord-022526-j9kg00qf 2623 17 done do VBN cord-022526-j9kg00qf 2623 18 under under IN cord-022526-j9kg00qf 2623 19 general general JJ cord-022526-j9kg00qf 2623 20 anesthesia anesthesia NN cord-022526-j9kg00qf 2623 21 with with IN cord-022526-j9kg00qf 2623 22 a a DT cord-022526-j9kg00qf 2623 23 cuffed cuff VBN cord-022526-j9kg00qf 2623 24 nasotracheal nasotracheal JJ cord-022526-j9kg00qf 2623 25 tube tube NN cord-022526-j9kg00qf 2623 26 . . . cord-022526-j9kg00qf 2624 1 In in IN cord-022526-j9kg00qf 2624 2 refractory refractory JJ cord-022526-j9kg00qf 2624 3 cases case NNS cord-022526-j9kg00qf 2624 4 , , , cord-022526-j9kg00qf 2624 5 intravenous intravenous JJ cord-022526-j9kg00qf 2624 6 administration administration NN cord-022526-j9kg00qf 2624 7 of of IN cord-022526-j9kg00qf 2624 8 isotonic isotonic JJ cord-022526-j9kg00qf 2624 9 fluid fluid NNP cord-022526-j9kg00qf 2624 10 containing contain VBG cord-022526-j9kg00qf 2624 11 0.9 0.9 CD cord-022526-j9kg00qf 2624 12 % % NN cord-022526-j9kg00qf 2624 13 NaCl nacl NN cord-022526-j9kg00qf 2624 14 and and CC cord-022526-j9kg00qf 2624 15 KCl KCl NNP cord-022526-j9kg00qf 2624 16 ( ( -LRB- cord-022526-j9kg00qf 2624 17 10 10 CD cord-022526-j9kg00qf 2624 18 to to TO cord-022526-j9kg00qf 2624 19 20 20 CD cord-022526-j9kg00qf 2624 20 mEq mEq NNS cord-022526-j9kg00qf 2624 21 / / SYM cord-022526-j9kg00qf 2624 22 L L NNP cord-022526-j9kg00qf 2624 23 ) ) -RRB- cord-022526-j9kg00qf 2624 24 for for IN cord-022526-j9kg00qf 2624 25 24 24 CD cord-022526-j9kg00qf 2624 26 hours hour NNS cord-022526-j9kg00qf 2624 27 at at IN cord-022526-j9kg00qf 2624 28 a a DT cord-022526-j9kg00qf 2624 29 rate rate NN cord-022526-j9kg00qf 2624 30 of of IN cord-022526-j9kg00qf 2624 31 50 50 CD cord-022526-j9kg00qf 2624 32 to to TO cord-022526-j9kg00qf 2624 33 100 100 CD cord-022526-j9kg00qf 2624 34 ml ml NNS cord-022526-j9kg00qf 2624 35 / / SYM cord-022526-j9kg00qf 2624 36 kg/ kg/ NNS cord-022526-j9kg00qf 2624 37 day day NN cord-022526-j9kg00qf 2624 38 along along IN cord-022526-j9kg00qf 2624 39 with with IN cord-022526-j9kg00qf 2624 40 esophageal esophageal JJ cord-022526-j9kg00qf 2624 41 relaxants relaxant NNS cord-022526-j9kg00qf 2624 42 such such JJ cord-022526-j9kg00qf 2624 43 as as IN cord-022526-j9kg00qf 2624 44 oxytocin oxytocin NN cord-022526-j9kg00qf 2624 45 may may MD cord-022526-j9kg00qf 2624 46 promote promote VB cord-022526-j9kg00qf 2624 47 hydration hydration NN cord-022526-j9kg00qf 2624 48 and and CC cord-022526-j9kg00qf 2624 49 softening softening NN cord-022526-j9kg00qf 2624 50 of of IN cord-022526-j9kg00qf 2624 51 the the DT cord-022526-j9kg00qf 2624 52 impaction impaction NN cord-022526-j9kg00qf 2624 53 and and CC cord-022526-j9kg00qf 2624 54 help help VB cord-022526-j9kg00qf 2624 55 prevent prevent VB cord-022526-j9kg00qf 2624 56 or or CC cord-022526-j9kg00qf 2624 57 alleviate alleviate VB cord-022526-j9kg00qf 2624 58 any any DT cord-022526-j9kg00qf 2624 59 electrolyte electrolyte NN cord-022526-j9kg00qf 2624 60 or or CC cord-022526-j9kg00qf 2624 61 acid acid NN cord-022526-j9kg00qf 2624 62 - - HYPH cord-022526-j9kg00qf 2624 63 base base NN cord-022526-j9kg00qf 2624 64 imbalances imbalance NNS cord-022526-j9kg00qf 2624 65 resulting result VBG cord-022526-j9kg00qf 2624 66 from from IN cord-022526-j9kg00qf 2624 67 salivary salivary JJ cord-022526-j9kg00qf 2624 68 losses loss NNS cord-022526-j9kg00qf 2624 69 of of IN cord-022526-j9kg00qf 2624 70 chloride chloride NN cord-022526-j9kg00qf 2624 71 , , , cord-022526-j9kg00qf 2624 72 sodium sodium NN cord-022526-j9kg00qf 2624 73 , , , cord-022526-j9kg00qf 2624 74 and and CC cord-022526-j9kg00qf 2624 75 potassium potassium NN cord-022526-j9kg00qf 2624 76 . . . cord-022526-j9kg00qf 2625 1 21 21 CD cord-022526-j9kg00qf 2626 1 One one PRP cord-022526-j9kg00qf 2626 2 should should MD cord-022526-j9kg00qf 2626 3 note note VB cord-022526-j9kg00qf 2626 4 that that IN cord-022526-j9kg00qf 2626 5 the the DT cord-022526-j9kg00qf 2626 6 effects effect NNS cord-022526-j9kg00qf 2626 7 of of IN cord-022526-j9kg00qf 2626 8 oxytocin oxytocin NN cord-022526-j9kg00qf 2626 9 on on IN cord-022526-j9kg00qf 2626 10 esophageal esophageal JJ cord-022526-j9kg00qf 2626 11 tone tone NN cord-022526-j9kg00qf 2626 12 occur occur VBP cord-022526-j9kg00qf 2626 13 in in IN cord-022526-j9kg00qf 2626 14 the the DT cord-022526-j9kg00qf 2626 15 proximal proximal JJ cord-022526-j9kg00qf 2626 16 two two CD cord-022526-j9kg00qf 2626 17 thirds third NNS cord-022526-j9kg00qf 2626 18 of of IN cord-022526-j9kg00qf 2626 19 the the DT cord-022526-j9kg00qf 2626 20 esophagus esophagus NN cord-022526-j9kg00qf 2626 21 and and CC cord-022526-j9kg00qf 2626 22 may may MD cord-022526-j9kg00qf 2626 23 not not RB cord-022526-j9kg00qf 2626 24 be be VB cord-022526-j9kg00qf 2626 25 effective effective JJ cord-022526-j9kg00qf 2626 26 for for IN cord-022526-j9kg00qf 2626 27 mucosa mucosa NN cord-022526-j9kg00qf 2626 28 has have VBZ cord-022526-j9kg00qf 2626 29 recovered recover VBN cord-022526-j9kg00qf 2626 30 as as IN cord-022526-j9kg00qf 2626 31 assessed assess VBN cord-022526-j9kg00qf 2626 32 by by IN cord-022526-j9kg00qf 2626 33 endoscopy endoscopy NN cord-022526-j9kg00qf 2626 34 , , , cord-022526-j9kg00qf 2626 35 one one PRP cord-022526-j9kg00qf 2626 36 can can MD cord-022526-j9kg00qf 2626 37 feed feed VB cord-022526-j9kg00qf 2626 38 the the DT cord-022526-j9kg00qf 2626 39 horse horse NN cord-022526-j9kg00qf 2626 40 soft soft JJ cord-022526-j9kg00qf 2626 41 food food NN cord-022526-j9kg00qf 2626 42 ( ( -LRB- cord-022526-j9kg00qf 2626 43 moistened moisten VBN cord-022526-j9kg00qf 2626 44 pellets pellet NNS cord-022526-j9kg00qf 2626 45 and and CC cord-022526-j9kg00qf 2626 46 bran bran NN cord-022526-j9kg00qf 2626 47 mashes mash NNS cord-022526-j9kg00qf 2626 48 ) ) -RRB- cord-022526-j9kg00qf 2626 49 . . . cord-022526-j9kg00qf 2627 1 One one PRP cord-022526-j9kg00qf 2627 2 can can MD cord-022526-j9kg00qf 2627 3 return return VB cord-022526-j9kg00qf 2627 4 the the DT cord-022526-j9kg00qf 2627 5 patient patient NN cord-022526-j9kg00qf 2627 6 gradually gradually RB cord-022526-j9kg00qf 2627 7 to to IN cord-022526-j9kg00qf 2627 8 a a DT cord-022526-j9kg00qf 2627 9 highquality highquality JJ cord-022526-j9kg00qf 2627 10 roughage roughage NN cord-022526-j9kg00qf 2627 11 diet diet NN cord-022526-j9kg00qf 2627 12 over over IN cord-022526-j9kg00qf 2627 13 7 7 CD cord-022526-j9kg00qf 2627 14 to to TO cord-022526-j9kg00qf 2627 15 21 21 CD cord-022526-j9kg00qf 2627 16 days day NNS cord-022526-j9kg00qf 2627 17 , , , cord-022526-j9kg00qf 2627 18 depending depend VBG cord-022526-j9kg00qf 2627 19 on on IN cord-022526-j9kg00qf 2627 20 the the DT cord-022526-j9kg00qf 2627 21 degree degree NN cord-022526-j9kg00qf 2627 22 of of IN cord-022526-j9kg00qf 2627 23 esophageal esophageal JJ cord-022526-j9kg00qf 2627 24 damage damage NN cord-022526-j9kg00qf 2627 25 induced induce VBN cord-022526-j9kg00qf 2627 26 by by IN cord-022526-j9kg00qf 2627 27 the the DT cord-022526-j9kg00qf 2627 28 impaction impaction NN cord-022526-j9kg00qf 2627 29 and and CC cord-022526-j9kg00qf 2627 30 the the DT cord-022526-j9kg00qf 2627 31 nature nature NN cord-022526-j9kg00qf 2627 32 of of IN cord-022526-j9kg00qf 2627 33 any any DT cord-022526-j9kg00qf 2627 34 underlying underlie VBG cord-022526-j9kg00qf 2627 35 disease disease NN cord-022526-j9kg00qf 2627 36 . . . cord-022526-j9kg00qf 2628 1 The the DT cord-022526-j9kg00qf 2628 2 prognosis prognosis NN cord-022526-j9kg00qf 2628 3 for for IN cord-022526-j9kg00qf 2628 4 survival survival NN cord-022526-j9kg00qf 2628 5 is be VBZ cord-022526-j9kg00qf 2628 6 good good JJ cord-022526-j9kg00qf 2628 7 ( ( -LRB- cord-022526-j9kg00qf 2628 8 78 78 CD cord-022526-j9kg00qf 2628 9 % % NN cord-022526-j9kg00qf 2628 10 ) ) -RRB- cord-022526-j9kg00qf 2628 11 , , , cord-022526-j9kg00qf 2628 12 but but CC cord-022526-j9kg00qf 2628 13 some some DT cord-022526-j9kg00qf 2628 14 horses horse NNS cord-022526-j9kg00qf 2628 15 may may MD cord-022526-j9kg00qf 2628 16 require require VB cord-022526-j9kg00qf 2628 17 permanent permanent JJ cord-022526-j9kg00qf 2628 18 dietary dietary JJ cord-022526-j9kg00qf 2628 19 modification modification NN cord-022526-j9kg00qf 2628 20 if if IN cord-022526-j9kg00qf 2628 21 persistent persistent JJ cord-022526-j9kg00qf 2628 22 chronic chronic JJ cord-022526-j9kg00qf 2628 23 obstruction obstruction NN cord-022526-j9kg00qf 2628 24 is be VBZ cord-022526-j9kg00qf 2628 25 a a DT cord-022526-j9kg00qf 2628 26 problem problem NN cord-022526-j9kg00qf 2628 27 . . . cord-022526-j9kg00qf 2629 1 3 3 CD cord-022526-j9kg00qf 2629 2 Aspiration aspiration NN cord-022526-j9kg00qf 2629 3 pneumonia pneumonia NN cord-022526-j9kg00qf 2629 4 and and CC cord-022526-j9kg00qf 2629 5 perforation perforation NN cord-022526-j9kg00qf 2629 6 are be VBP cord-022526-j9kg00qf 2629 7 potential potential JJ cord-022526-j9kg00qf 2629 8 complications complication NNS cord-022526-j9kg00qf 2629 9 of of IN cord-022526-j9kg00qf 2629 10 severe severe JJ cord-022526-j9kg00qf 2629 11 or or CC cord-022526-j9kg00qf 2629 12 prolonged prolonged JJ cord-022526-j9kg00qf 2629 13 esophageal esophageal JJ cord-022526-j9kg00qf 2629 14 obstructions obstruction NNS cord-022526-j9kg00qf 2629 15 . . . cord-022526-j9kg00qf 2630 1 If if IN cord-022526-j9kg00qf 2630 2 aspiration aspiration NN cord-022526-j9kg00qf 2630 3 is be VBZ cord-022526-j9kg00qf 2630 4 suspected suspect VBN cord-022526-j9kg00qf 2630 5 , , , cord-022526-j9kg00qf 2630 6 administration administration NN cord-022526-j9kg00qf 2630 7 of of IN cord-022526-j9kg00qf 2630 8 broad broad JJ cord-022526-j9kg00qf 2630 9 - - HYPH cord-022526-j9kg00qf 2630 10 spectrum spectrum NN cord-022526-j9kg00qf 2630 11 antibiotics antibiotic NNS cord-022526-j9kg00qf 2630 12 that that WDT cord-022526-j9kg00qf 2630 13 are be VBP cord-022526-j9kg00qf 2630 14 effective effective JJ cord-022526-j9kg00qf 2630 15 against against IN cord-022526-j9kg00qf 2630 16 gram gram NN cord-022526-j9kg00qf 2630 17 - - HYPH cord-022526-j9kg00qf 2630 18 positive positive JJ cord-022526-j9kg00qf 2630 19 and and CC cord-022526-j9kg00qf 2630 20 gram gram JJ cord-022526-j9kg00qf 2630 21 - - HYPH cord-022526-j9kg00qf 2630 22 negative negative JJ cord-022526-j9kg00qf 2630 23 organisms organism NNS cord-022526-j9kg00qf 2630 24 , , , cord-022526-j9kg00qf 2630 25 including include VBG cord-022526-j9kg00qf 2630 26 metronidazole metronidazole NNP cord-022526-j9kg00qf 2630 27 ( ( -LRB- cord-022526-j9kg00qf 2630 28 20 20 CD cord-022526-j9kg00qf 2630 29 mg mg NNP cord-022526-j9kg00qf 2630 30 / / SYM cord-022526-j9kg00qf 2630 31 kg kg CC cord-022526-j9kg00qf 2630 32 orally orally RB cord-022526-j9kg00qf 2630 33 every every DT cord-022526-j9kg00qf 2630 34 8 8 CD cord-022526-j9kg00qf 2630 35 hours hour NNS cord-022526-j9kg00qf 2630 36 ) ) -RRB- cord-022526-j9kg00qf 2630 37 for for IN cord-022526-j9kg00qf 2630 38 anaerobes anaerobe NNS cord-022526-j9kg00qf 2630 39 is be VBZ cord-022526-j9kg00qf 2630 40 advisable advisable JJ cord-022526-j9kg00qf 2630 41 . . . cord-022526-j9kg00qf 2631 1 A a DT cord-022526-j9kg00qf 2631 2 subsequent subsequent JJ cord-022526-j9kg00qf 2631 3 section section NN cord-022526-j9kg00qf 2631 4 describes describe VBZ cord-022526-j9kg00qf 2631 5 treatment treatment NN cord-022526-j9kg00qf 2631 6 of of IN cord-022526-j9kg00qf 2631 7 esophageal esophageal JJ cord-022526-j9kg00qf 2631 8 perforation perforation NN cord-022526-j9kg00qf 2631 9 or or CC cord-022526-j9kg00qf 2631 10 rupture rupture NN cord-022526-j9kg00qf 2631 11 . . . cord-022526-j9kg00qf 2632 1 Esophagitis Esophagitis NNP cord-022526-j9kg00qf 2632 2 refers refer VBZ cord-022526-j9kg00qf 2632 3 to to IN cord-022526-j9kg00qf 2632 4 a a DT cord-022526-j9kg00qf 2632 5 clinical clinical JJ cord-022526-j9kg00qf 2632 6 syndrome syndrome NN cord-022526-j9kg00qf 2632 7 of of IN cord-022526-j9kg00qf 2632 8 esophageal esophageal JJ cord-022526-j9kg00qf 2632 9 inflammation inflammation NN cord-022526-j9kg00qf 2632 10 that that WDT cord-022526-j9kg00qf 2632 11 may may MD cord-022526-j9kg00qf 2632 12 or or CC cord-022526-j9kg00qf 2632 13 may may MD cord-022526-j9kg00qf 2632 14 not not RB cord-022526-j9kg00qf 2632 15 be be VB cord-022526-j9kg00qf 2632 16 ulcerative ulcerative JJ cord-022526-j9kg00qf 2632 17 . . . cord-022526-j9kg00qf 2633 1 The the DT cord-022526-j9kg00qf 2633 2 major major JJ cord-022526-j9kg00qf 2633 3 protective protective JJ cord-022526-j9kg00qf 2633 4 mechanisms mechanism NNS cord-022526-j9kg00qf 2633 5 of of IN cord-022526-j9kg00qf 2633 6 the the DT cord-022526-j9kg00qf 2633 7 esophageal esophageal JJ cord-022526-j9kg00qf 2633 8 mucosa mucosa NN cord-022526-j9kg00qf 2633 9 include include VBP cord-022526-j9kg00qf 2633 10 salivary salivary NN cord-022526-j9kg00qf 2633 11 and and CC cord-022526-j9kg00qf 2633 12 food food NN cord-022526-j9kg00qf 2633 13 material material NN cord-022526-j9kg00qf 2633 14 buffers buffer NNS cord-022526-j9kg00qf 2633 15 , , , cord-022526-j9kg00qf 2633 16 normal normal JJ cord-022526-j9kg00qf 2633 17 peristaltic peristaltic JJ cord-022526-j9kg00qf 2633 18 motility motility NN cord-022526-j9kg00qf 2633 19 , , , cord-022526-j9kg00qf 2633 20 and and CC cord-022526-j9kg00qf 2633 21 the the DT cord-022526-j9kg00qf 2633 22 barrier barrier NN cord-022526-j9kg00qf 2633 23 formed form VBN cord-022526-j9kg00qf 2633 24 by by IN cord-022526-j9kg00qf 2633 25 the the DT cord-022526-j9kg00qf 2633 26 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2633 27 sphincter sphincter NN cord-022526-j9kg00qf 2633 28 . . . cord-022526-j9kg00qf 2634 1 Reflux reflux NN cord-022526-j9kg00qf 2634 2 esophagitis esophagitis NN cord-022526-j9kg00qf 2634 3 is be VBZ cord-022526-j9kg00qf 2634 4 caused cause VBN cord-022526-j9kg00qf 2634 5 by by IN cord-022526-j9kg00qf 2634 6 repeated repeat VBN cord-022526-j9kg00qf 2634 7 episodes episode NNS cord-022526-j9kg00qf 2634 8 of of IN cord-022526-j9kg00qf 2634 9 gastric gastric JJ cord-022526-j9kg00qf 2634 10 fluid fluid JJ cord-022526-j9kg00qf 2634 11 regurgitation regurgitation NN cord-022526-j9kg00qf 2634 12 into into IN cord-022526-j9kg00qf 2634 13 the the DT cord-022526-j9kg00qf 2634 14 distal distal JJ cord-022526-j9kg00qf 2634 15 esophagus esophagus NN cord-022526-j9kg00qf 2634 16 and and CC cord-022526-j9kg00qf 2634 17 subsequent subsequent JJ cord-022526-j9kg00qf 2634 18 chemical chemical NN cord-022526-j9kg00qf 2634 19 injury injury NN cord-022526-j9kg00qf 2634 20 to to IN cord-022526-j9kg00qf 2634 21 the the DT cord-022526-j9kg00qf 2634 22 mucosa mucosa NN cord-022526-j9kg00qf 2634 23 ( ( -LRB- cord-022526-j9kg00qf 2634 24 Figure figure NN cord-022526-j9kg00qf 2634 25 13 13 CD cord-022526-j9kg00qf 2634 26 distal distal JJ cord-022526-j9kg00qf 2634 27 obstructions obstruction NNS cord-022526-j9kg00qf 2634 28 . . . cord-022526-j9kg00qf 2635 1 19 19 CD cord-022526-j9kg00qf 2635 2 , , , cord-022526-j9kg00qf 2635 3 20 20 CD cord-022526-j9kg00qf 2635 4 Rarely rarely RB cord-022526-j9kg00qf 2635 5 , , , cord-022526-j9kg00qf 2635 6 esophageal esophageal JJ cord-022526-j9kg00qf 2635 7 obstruction obstruction NN cord-022526-j9kg00qf 2635 8 ultimately ultimately RB cord-022526-j9kg00qf 2635 9 may may MD cord-022526-j9kg00qf 2635 10 require require VB cord-022526-j9kg00qf 2635 11 esophagotomy esophagotomy NN cord-022526-j9kg00qf 2635 12 to to TO cord-022526-j9kg00qf 2635 13 relieve relieve VB cord-022526-j9kg00qf 2635 14 the the DT cord-022526-j9kg00qf 2635 15 impaction impaction NN cord-022526-j9kg00qf 2635 16 . . . cord-022526-j9kg00qf 2636 1 One one PRP cord-022526-j9kg00qf 2636 2 must must MD cord-022526-j9kg00qf 2636 3 enforce enforce VB cord-022526-j9kg00qf 2636 4 strict strict JJ cord-022526-j9kg00qf 2636 5 restriction restriction NN cord-022526-j9kg00qf 2636 6 of of IN cord-022526-j9kg00qf 2636 7 food food NN cord-022526-j9kg00qf 2636 8 and and CC cord-022526-j9kg00qf 2636 9 water water NN cord-022526-j9kg00qf 2636 10 , , , cord-022526-j9kg00qf 2636 11 including include VBG cord-022526-j9kg00qf 2636 12 access access NN cord-022526-j9kg00qf 2636 13 to to IN cord-022526-j9kg00qf 2636 14 bedding bedding NN cord-022526-j9kg00qf 2636 15 material material NN cord-022526-j9kg00qf 2636 16 , , , cord-022526-j9kg00qf 2636 17 until until IN cord-022526-j9kg00qf 2636 18 the the DT cord-022526-j9kg00qf 2636 19 obstruction obstruction NN cord-022526-j9kg00qf 2636 20 is be VBZ cord-022526-j9kg00qf 2636 21 resolved resolve VBN cord-022526-j9kg00qf 2636 22 and and CC cord-022526-j9kg00qf 2636 23 the the DT cord-022526-j9kg00qf 2636 24 esophagus esophagus NN cord-022526-j9kg00qf 2636 25 has have VBZ cord-022526-j9kg00qf 2636 26 regained regain VBN cord-022526-j9kg00qf 2636 27 function function NN cord-022526-j9kg00qf 2636 28 . . . cord-022526-j9kg00qf 2637 1 Systemic systemic JJ cord-022526-j9kg00qf 2637 2 effects effect NNS cord-022526-j9kg00qf 2637 3 of of IN cord-022526-j9kg00qf 2637 4 dysphagia dysphagia NN cord-022526-j9kg00qf 2637 5 associated associate VBN cord-022526-j9kg00qf 2637 6 with with IN cord-022526-j9kg00qf 2637 7 esophageal esophageal JJ cord-022526-j9kg00qf 2637 8 impaction impaction NN cord-022526-j9kg00qf 2637 9 include include VBP cord-022526-j9kg00qf 2637 10 dehydration dehydration NN cord-022526-j9kg00qf 2637 11 , , , cord-022526-j9kg00qf 2637 12 hyponatremia hyponatremia NN cord-022526-j9kg00qf 2637 13 , , , cord-022526-j9kg00qf 2637 14 hypochloremia hypochloremia NN cord-022526-j9kg00qf 2637 15 , , , cord-022526-j9kg00qf 2637 16 and and CC cord-022526-j9kg00qf 2637 17 metabolic metabolic JJ cord-022526-j9kg00qf 2637 18 alkalosis alkalosis NN cord-022526-j9kg00qf 2637 19 from from IN cord-022526-j9kg00qf 2637 20 prolonged prolonged JJ cord-022526-j9kg00qf 2637 21 loss loss NN cord-022526-j9kg00qf 2637 22 of of IN cord-022526-j9kg00qf 2637 23 salivary salivary NN cord-022526-j9kg00qf 2637 24 free free JJ cord-022526-j9kg00qf 2637 25 water water NN cord-022526-j9kg00qf 2637 26 and and CC cord-022526-j9kg00qf 2637 27 electrolytes electrolyte NNS cord-022526-j9kg00qf 2637 28 . . . cord-022526-j9kg00qf 2638 1 21 21 CD cord-022526-j9kg00qf 2639 1 If if IN cord-022526-j9kg00qf 2639 2 the the DT cord-022526-j9kg00qf 2639 3 duration duration NN cord-022526-j9kg00qf 2639 4 of of IN cord-022526-j9kg00qf 2639 5 a a DT cord-022526-j9kg00qf 2639 6 complete complete JJ cord-022526-j9kg00qf 2639 7 esophageal esophageal JJ cord-022526-j9kg00qf 2639 8 obstruction obstruction NN cord-022526-j9kg00qf 2639 9 is be VBZ cord-022526-j9kg00qf 2639 10 48 48 CD cord-022526-j9kg00qf 2639 11 hours hour NNS cord-022526-j9kg00qf 2639 12 or or CC cord-022526-j9kg00qf 2639 13 longer long JJR cord-022526-j9kg00qf 2639 14 , , , cord-022526-j9kg00qf 2639 15 one one PRP cord-022526-j9kg00qf 2639 16 should should MD cord-022526-j9kg00qf 2639 17 correct correct VB cord-022526-j9kg00qf 2639 18 dehydration dehydration NN cord-022526-j9kg00qf 2639 19 and and CC cord-022526-j9kg00qf 2639 20 electrolyte electrolyte NN cord-022526-j9kg00qf 2639 21 and and CC cord-022526-j9kg00qf 2639 22 acid acid NN cord-022526-j9kg00qf 2639 23 - - HYPH cord-022526-j9kg00qf 2639 24 base base NN cord-022526-j9kg00qf 2639 25 imbalances imbalance NNS cord-022526-j9kg00qf 2639 26 . . . cord-022526-j9kg00qf 2640 1 One one PRP cord-022526-j9kg00qf 2640 2 can can MD cord-022526-j9kg00qf 2640 3 restore restore VB cord-022526-j9kg00qf 2640 4 fluid fluid NN cord-022526-j9kg00qf 2640 5 and and CC cord-022526-j9kg00qf 2640 6 electrolyte electrolyte JJ cord-022526-j9kg00qf 2640 7 balance balance NN cord-022526-j9kg00qf 2640 8 with with IN cord-022526-j9kg00qf 2640 9 oral oral JJ cord-022526-j9kg00qf 2640 10 electrolyte electrolyte JJ cord-022526-j9kg00qf 2640 11 solutions solution NNS cord-022526-j9kg00qf 2640 12 if if IN cord-022526-j9kg00qf 2640 13 the the DT cord-022526-j9kg00qf 2640 14 patient patient NN cord-022526-j9kg00qf 2640 15 is be VBZ cord-022526-j9kg00qf 2640 16 less less JJR cord-022526-j9kg00qf 2640 17 than than IN cord-022526-j9kg00qf 2640 18 6 6 CD cord-022526-j9kg00qf 2640 19 % % NN cord-022526-j9kg00qf 2640 20 to to TO cord-022526-j9kg00qf 2640 21 7 7 CD cord-022526-j9kg00qf 2640 22 % % NN cord-022526-j9kg00qf 2640 23 dehydrated dehydrated JJ cord-022526-j9kg00qf 2640 24 and and CC cord-022526-j9kg00qf 2640 25 the the DT cord-022526-j9kg00qf 2640 26 esophageal esophageal JJ cord-022526-j9kg00qf 2640 27 obstruction obstruction NN cord-022526-j9kg00qf 2640 28 is be VBZ cord-022526-j9kg00qf 2640 29 resolved resolve VBN cord-022526-j9kg00qf 2640 30 . . . cord-022526-j9kg00qf 2641 1 Horses horse NNS cord-022526-j9kg00qf 2641 2 that that WDT cord-022526-j9kg00qf 2641 3 are be VBP cord-022526-j9kg00qf 2641 4 greater great JJR cord-022526-j9kg00qf 2641 5 than than IN cord-022526-j9kg00qf 2641 6 6 6 CD cord-022526-j9kg00qf 2641 7 % % NN cord-022526-j9kg00qf 2641 8 to to TO cord-022526-j9kg00qf 2641 9 7 7 CD cord-022526-j9kg00qf 2641 10 % % NN cord-022526-j9kg00qf 2641 11 dehydrated dehydrated JJ cord-022526-j9kg00qf 2641 12 or or CC cord-022526-j9kg00qf 2641 13 those those DT cord-022526-j9kg00qf 2641 14 that that WDT cord-022526-j9kg00qf 2641 15 have have VBP cord-022526-j9kg00qf 2641 16 a a DT cord-022526-j9kg00qf 2641 17 refractory refractory JJ cord-022526-j9kg00qf 2641 18 obstruction obstruction NN cord-022526-j9kg00qf 2641 19 or or CC cord-022526-j9kg00qf 2641 20 moderate moderate JJ cord-022526-j9kg00qf 2641 21 to to IN cord-022526-j9kg00qf 2641 22 severe severe JJ cord-022526-j9kg00qf 2641 23 electrolyte electrolyte JJ cord-022526-j9kg00qf 2641 24 imbalances imbalance NNS cord-022526-j9kg00qf 2641 25 may may MD cord-022526-j9kg00qf 2641 26 require require VB cord-022526-j9kg00qf 2641 27 intravenous intravenous JJ cord-022526-j9kg00qf 2641 28 fluid fluid NN cord-022526-j9kg00qf 2641 29 therapy therapy NN cord-022526-j9kg00qf 2641 30 with with IN cord-022526-j9kg00qf 2641 31 solutions solution NNS cord-022526-j9kg00qf 2641 32 containing contain VBG cord-022526-j9kg00qf 2641 33 0.9 0.9 CD cord-022526-j9kg00qf 2641 34 % % NN cord-022526-j9kg00qf 2641 35 NaCl nacl NN cord-022526-j9kg00qf 2641 36 and and CC cord-022526-j9kg00qf 2641 37 KCl KCl NNP cord-022526-j9kg00qf 2641 38 ( ( -LRB- cord-022526-j9kg00qf 2641 39 10 10 CD cord-022526-j9kg00qf 2641 40 to to TO cord-022526-j9kg00qf 2641 41 20 20 CD cord-022526-j9kg00qf 2641 42 mEq mEq NNS cord-022526-j9kg00qf 2641 43 / / SYM cord-022526-j9kg00qf 2641 44 L L NNP cord-022526-j9kg00qf 2641 45 ) ) -RRB- cord-022526-j9kg00qf 2641 46 . . . cord-022526-j9kg00qf 2642 1 One one PRP cord-022526-j9kg00qf 2642 2 should should MD cord-022526-j9kg00qf 2642 3 perform perform VB cord-022526-j9kg00qf 2642 4 esophageal esophageal JJ cord-022526-j9kg00qf 2642 5 endoscopy endoscopy NN cord-022526-j9kg00qf 2642 6 after after IN cord-022526-j9kg00qf 2642 7 relief relief NN cord-022526-j9kg00qf 2642 8 of of IN cord-022526-j9kg00qf 2642 9 the the DT cord-022526-j9kg00qf 2642 10 impaction impaction NN cord-022526-j9kg00qf 2642 11 to to TO cord-022526-j9kg00qf 2642 12 determine determine VB cord-022526-j9kg00qf 2642 13 whether whether IN cord-022526-j9kg00qf 2642 14 any any DT cord-022526-j9kg00qf 2642 15 complications complication NNS cord-022526-j9kg00qf 2642 16 of of IN cord-022526-j9kg00qf 2642 17 the the DT cord-022526-j9kg00qf 2642 18 impaction impaction NN cord-022526-j9kg00qf 2642 19 have have VBP cord-022526-j9kg00qf 2642 20 developed develop VBN cord-022526-j9kg00qf 2642 21 or or CC cord-022526-j9kg00qf 2642 22 if if IN cord-022526-j9kg00qf 2642 23 a a DT cord-022526-j9kg00qf 2642 24 primary primary JJ cord-022526-j9kg00qf 2642 25 cause cause NN cord-022526-j9kg00qf 2642 26 of of IN cord-022526-j9kg00qf 2642 27 the the DT cord-022526-j9kg00qf 2642 28 obstruction obstruction NN cord-022526-j9kg00qf 2642 29 is be VBZ cord-022526-j9kg00qf 2642 30 present present JJ cord-022526-j9kg00qf 2642 31 . . . cord-022526-j9kg00qf 2643 1 Endoscopic endoscopic JJ cord-022526-j9kg00qf 2643 2 examination examination NN cord-022526-j9kg00qf 2643 3 is be VBZ cord-022526-j9kg00qf 2643 4 critical critical JJ cord-022526-j9kg00qf 2643 5 to to TO cord-022526-j9kg00qf 2643 6 determine determine VB cord-022526-j9kg00qf 2643 7 the the DT cord-022526-j9kg00qf 2643 8 postobstruction postobstruction NN cord-022526-j9kg00qf 2643 9 treatment treatment NN cord-022526-j9kg00qf 2643 10 plan plan NN cord-022526-j9kg00qf 2643 11 and and CC cord-022526-j9kg00qf 2643 12 for for IN cord-022526-j9kg00qf 2643 13 follow follow VB cord-022526-j9kg00qf 2643 14 - - HYPH cord-022526-j9kg00qf 2643 15 up up NN cord-022526-j9kg00qf 2643 16 evaluation evaluation NN cord-022526-j9kg00qf 2643 17 of of IN cord-022526-j9kg00qf 2643 18 esophageal esophageal JJ cord-022526-j9kg00qf 2643 19 healing healing NN cord-022526-j9kg00qf 2643 20 . . . cord-022526-j9kg00qf 2644 1 One one PRP cord-022526-j9kg00qf 2644 2 should should MD cord-022526-j9kg00qf 2644 3 reevaluate reevaluate VB cord-022526-j9kg00qf 2644 4 the the DT cord-022526-j9kg00qf 2644 5 horse horse NN cord-022526-j9kg00qf 2644 6 every every DT cord-022526-j9kg00qf 2644 7 2 2 CD cord-022526-j9kg00qf 2644 8 to to TO cord-022526-j9kg00qf 2644 9 4 4 CD cord-022526-j9kg00qf 2644 10 weeks week NNS cord-022526-j9kg00qf 2644 11 following follow VBG cord-022526-j9kg00qf 2644 12 resolution resolution NN cord-022526-j9kg00qf 2644 13 of of IN cord-022526-j9kg00qf 2644 14 the the DT cord-022526-j9kg00qf 2644 15 impaction impaction NN cord-022526-j9kg00qf 2644 16 if if IN cord-022526-j9kg00qf 2644 17 one one CD cord-022526-j9kg00qf 2644 18 notes note VBZ cord-022526-j9kg00qf 2644 19 esophageal esophageal VBP cord-022526-j9kg00qf 2644 20 dilation dilation NN cord-022526-j9kg00qf 2644 21 or or CC cord-022526-j9kg00qf 2644 22 mucosal mucosal JJ cord-022526-j9kg00qf 2644 23 injury injury NN cord-022526-j9kg00qf 2644 24 . . . cord-022526-j9kg00qf 2645 1 Additional additional JJ cord-022526-j9kg00qf 2645 2 evaluation evaluation NN cord-022526-j9kg00qf 2645 3 via via IN cord-022526-j9kg00qf 2645 4 radiography radiography NN cord-022526-j9kg00qf 2645 5 may may MD cord-022526-j9kg00qf 2645 6 be be VB cord-022526-j9kg00qf 2645 7 warranted warrant VBN cord-022526-j9kg00qf 2645 8 to to TO cord-022526-j9kg00qf 2645 9 assess assess VB cord-022526-j9kg00qf 2645 10 motility motility NN cord-022526-j9kg00qf 2645 11 and and CC cord-022526-j9kg00qf 2645 12 transit transit NN cord-022526-j9kg00qf 2645 13 times time NNS cord-022526-j9kg00qf 2645 14 . . . cord-022526-j9kg00qf 2646 1 Dilation dilation NN cord-022526-j9kg00qf 2646 2 proximal proximal JJ cord-022526-j9kg00qf 2646 3 to to IN cord-022526-j9kg00qf 2646 4 the the DT cord-022526-j9kg00qf 2646 5 site site NN cord-022526-j9kg00qf 2646 6 of of IN cord-022526-j9kg00qf 2646 7 obstruction obstruction NN cord-022526-j9kg00qf 2646 8 , , , cord-022526-j9kg00qf 2646 9 mucosal mucosal JJ cord-022526-j9kg00qf 2646 10 injury injury NN cord-022526-j9kg00qf 2646 11 from from IN cord-022526-j9kg00qf 2646 12 trauma trauma NN cord-022526-j9kg00qf 2646 13 , , , cord-022526-j9kg00qf 2646 14 stricture stricture NN cord-022526-j9kg00qf 2646 15 formation formation NN cord-022526-j9kg00qf 2646 16 , , , cord-022526-j9kg00qf 2646 17 formation formation NN cord-022526-j9kg00qf 2646 18 of of IN cord-022526-j9kg00qf 2646 19 a a DT cord-022526-j9kg00qf 2646 20 diverticulum diverticulum NN cord-022526-j9kg00qf 2646 21 , , , cord-022526-j9kg00qf 2646 22 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2646 23 , , , cord-022526-j9kg00qf 2646 24 and and CC cord-022526-j9kg00qf 2646 25 esophagitis esophagitis NN cord-022526-j9kg00qf 2646 26 are be VBP cord-022526-j9kg00qf 2646 27 sequelae sequela NNS cord-022526-j9kg00qf 2646 28 to to IN cord-022526-j9kg00qf 2646 29 esophageal esophageal JJ cord-022526-j9kg00qf 2646 30 obstruction obstruction NN cord-022526-j9kg00qf 2646 31 that that WDT cord-022526-j9kg00qf 2646 32 predispose predispose VBP cord-022526-j9kg00qf 2646 33 patients patient NNS cord-022526-j9kg00qf 2646 34 to to IN cord-022526-j9kg00qf 2646 35 reobstruction reobstruction NN cord-022526-j9kg00qf 2646 36 . . . cord-022526-j9kg00qf 2647 1 The the DT cord-022526-j9kg00qf 2647 2 rate rate NN cord-022526-j9kg00qf 2647 3 of of IN cord-022526-j9kg00qf 2647 4 reobstruction reobstruction NN cord-022526-j9kg00qf 2647 5 may may MD cord-022526-j9kg00qf 2647 6 be be VB cord-022526-j9kg00qf 2647 7 as as RB cord-022526-j9kg00qf 2647 8 high high JJ cord-022526-j9kg00qf 2647 9 as as IN cord-022526-j9kg00qf 2647 10 37 37 CD cord-022526-j9kg00qf 2647 11 % % NN cord-022526-j9kg00qf 2647 12 . . . cord-022526-j9kg00qf 2648 1 Depending depend VBG cord-022526-j9kg00qf 2648 2 on on IN cord-022526-j9kg00qf 2648 3 the the DT cord-022526-j9kg00qf 2648 4 duration duration NN cord-022526-j9kg00qf 2648 5 of of IN cord-022526-j9kg00qf 2648 6 the the DT cord-022526-j9kg00qf 2648 7 obstruction obstruction NN cord-022526-j9kg00qf 2648 8 and and CC cord-022526-j9kg00qf 2648 9 the the DT cord-022526-j9kg00qf 2648 10 degree degree NN cord-022526-j9kg00qf 2648 11 of of IN cord-022526-j9kg00qf 2648 12 trauma trauma NN cord-022526-j9kg00qf 2648 13 or or CC cord-022526-j9kg00qf 2648 14 dilation dilation NN cord-022526-j9kg00qf 2648 15 , , , cord-022526-j9kg00qf 2648 16 the the DT cord-022526-j9kg00qf 2648 17 risk risk NN cord-022526-j9kg00qf 2648 18 of of IN cord-022526-j9kg00qf 2648 19 reobstruction reobstruction NN cord-022526-j9kg00qf 2648 20 is be VBZ cord-022526-j9kg00qf 2648 21 high high JJ cord-022526-j9kg00qf 2648 22 for for IN cord-022526-j9kg00qf 2648 23 24 24 CD cord-022526-j9kg00qf 2648 24 to to TO cord-022526-j9kg00qf 2648 25 48 48 CD cord-022526-j9kg00qf 2648 26 hours hour NNS cord-022526-j9kg00qf 2648 27 or or CC cord-022526-j9kg00qf 2648 28 longer long RBR cord-022526-j9kg00qf 2648 29 , , , cord-022526-j9kg00qf 2648 30 thus thus RB cord-022526-j9kg00qf 2648 31 one one PRP cord-022526-j9kg00qf 2648 32 should should MD cord-022526-j9kg00qf 2648 33 withhold withhold VB cord-022526-j9kg00qf 2648 34 food food NN cord-022526-j9kg00qf 2648 35 for for IN cord-022526-j9kg00qf 2648 36 at at RB cord-022526-j9kg00qf 2648 37 least least RBS cord-022526-j9kg00qf 2648 38 24 24 CD cord-022526-j9kg00qf 2648 39 to to TO cord-022526-j9kg00qf 2648 40 48 48 CD cord-022526-j9kg00qf 2648 41 hours hour NNS cord-022526-j9kg00qf 2648 42 after after IN cord-022526-j9kg00qf 2648 43 resolution resolution NN cord-022526-j9kg00qf 2648 44 of of IN cord-022526-j9kg00qf 2648 45 the the DT cord-022526-j9kg00qf 2648 46 obstruction obstruction NN cord-022526-j9kg00qf 2648 47 . . . cord-022526-j9kg00qf 2649 1 Sucralfate sucralfate JJ cord-022526-j9kg00qf 2650 1 ( ( -LRB- cord-022526-j9kg00qf 2650 2 20 20 CD cord-022526-j9kg00qf 2650 3 mg mg NNP cord-022526-j9kg00qf 2650 4 / / SYM cord-022526-j9kg00qf 2650 5 kg kg CC cord-022526-j9kg00qf 2650 6 orally orally RB cord-022526-j9kg00qf 2650 7 every every DT cord-022526-j9kg00qf 2650 8 6 6 CD cord-022526-j9kg00qf 2650 9 hours hour NNS cord-022526-j9kg00qf 2650 10 ) ) -RRB- cord-022526-j9kg00qf 2650 11 may may MD cord-022526-j9kg00qf 2650 12 hasten hasten VB cord-022526-j9kg00qf 2650 13 healing healing NN cord-022526-j9kg00qf 2650 14 if if IN cord-022526-j9kg00qf 2650 15 esophageal esophageal JJ cord-022526-j9kg00qf 2650 16 ulceration ulceration NN cord-022526-j9kg00qf 2650 17 is be VBZ cord-022526-j9kg00qf 2650 18 evident evident JJ cord-022526-j9kg00qf 2650 19 , , , cord-022526-j9kg00qf 2650 20 but but CC cord-022526-j9kg00qf 2650 21 the the DT cord-022526-j9kg00qf 2650 22 efficacy efficacy NN cord-022526-j9kg00qf 2650 23 of of IN cord-022526-j9kg00qf 2650 24 sucralfate sucralfate NN cord-022526-j9kg00qf 2650 25 for for IN cord-022526-j9kg00qf 2650 26 this this DT cord-022526-j9kg00qf 2650 27 purpose purpose NN cord-022526-j9kg00qf 2650 28 is be VBZ cord-022526-j9kg00qf 2650 29 not not RB cord-022526-j9kg00qf 2650 30 established establish VBN cord-022526-j9kg00qf 2650 31 . . . cord-022526-j9kg00qf 2651 1 Some some DT cord-022526-j9kg00qf 2651 2 clinicians clinician NNS cord-022526-j9kg00qf 2651 3 suggest suggest VBP cord-022526-j9kg00qf 2651 4 that that IN cord-022526-j9kg00qf 2651 5 administration administration NN cord-022526-j9kg00qf 2651 6 of of IN cord-022526-j9kg00qf 2651 7 a a DT cord-022526-j9kg00qf 2651 8 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 2651 9 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2651 10 drug drug NN cord-022526-j9kg00qf 2651 11 ( ( -LRB- cord-022526-j9kg00qf 2651 12 NSAID NSAID NNP cord-022526-j9kg00qf 2651 13 ) ) -RRB- cord-022526-j9kg00qf 2651 14 such such JJ cord-022526-j9kg00qf 2651 15 as as IN cord-022526-j9kg00qf 2651 16 flunixin flunixin NNP cord-022526-j9kg00qf 2651 17 meglumine meglumine NNP cord-022526-j9kg00qf 2651 18 ( ( -LRB- cord-022526-j9kg00qf 2651 19 1 1 CD cord-022526-j9kg00qf 2651 20 mg mg NNP cord-022526-j9kg00qf 2651 21 / / SYM cord-022526-j9kg00qf 2651 22 kg kg XX cord-022526-j9kg00qf 2651 23 orally orally RB cord-022526-j9kg00qf 2651 24 or or CC cord-022526-j9kg00qf 2651 25 intravenously intravenously RB cord-022526-j9kg00qf 2651 26 every every DT cord-022526-j9kg00qf 2651 27 12 12 CD cord-022526-j9kg00qf 2651 28 hours hour NNS cord-022526-j9kg00qf 2651 29 ) ) -RRB- cord-022526-j9kg00qf 2651 30 or or CC cord-022526-j9kg00qf 2651 31 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 2651 32 ( ( -LRB- cord-022526-j9kg00qf 2651 33 1 1 CD cord-022526-j9kg00qf 2651 34 to to IN cord-022526-j9kg00qf 2651 35 2 2 CD cord-022526-j9kg00qf 2651 36 mg mg NNP cord-022526-j9kg00qf 2651 37 / / SYM cord-022526-j9kg00qf 2651 38 kg kg XX cord-022526-j9kg00qf 2651 39 orally orally RB cord-022526-j9kg00qf 2651 40 or or CC cord-022526-j9kg00qf 2651 41 intravenously intravenously RB cord-022526-j9kg00qf 2651 42 every every DT cord-022526-j9kg00qf 2651 43 12 12 CD cord-022526-j9kg00qf 2651 44 to to TO cord-022526-j9kg00qf 2651 45 24 24 CD cord-022526-j9kg00qf 2651 46 hours hour NNS cord-022526-j9kg00qf 2651 47 ) ) -RRB- cord-022526-j9kg00qf 2651 48 for for IN cord-022526-j9kg00qf 2651 49 2 2 CD cord-022526-j9kg00qf 2651 50 to to TO cord-022526-j9kg00qf 2651 51 4 4 CD cord-022526-j9kg00qf 2651 52 weeks week NNS cord-022526-j9kg00qf 2651 53 after after IN cord-022526-j9kg00qf 2651 54 resolution resolution NN cord-022526-j9kg00qf 2651 55 of of IN cord-022526-j9kg00qf 2651 56 the the DT cord-022526-j9kg00qf 2651 57 impaction impaction NN cord-022526-j9kg00qf 2651 58 may may MD cord-022526-j9kg00qf 2651 59 reduce reduce VB cord-022526-j9kg00qf 2651 60 the the DT cord-022526-j9kg00qf 2651 61 development development NN cord-022526-j9kg00qf 2651 62 of of IN cord-022526-j9kg00qf 2651 63 strictures stricture NNS cord-022526-j9kg00qf 2651 64 . . . cord-022526-j9kg00qf 2652 1 Judicious judicious JJ cord-022526-j9kg00qf 2652 2 use use NN cord-022526-j9kg00qf 2652 3 of of IN cord-022526-j9kg00qf 2652 4 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 2652 5 is be VBZ cord-022526-j9kg00qf 2652 6 recommended recommend VBN cord-022526-j9kg00qf 2652 7 to to TO cord-022526-j9kg00qf 2652 8 prevent prevent VB cord-022526-j9kg00qf 2652 9 NSAID NSAID NNP cord-022526-j9kg00qf 2652 10 - - HYPH cord-022526-j9kg00qf 2652 11 induced induce VBN cord-022526-j9kg00qf 2652 12 worsening worsen VBG cord-022526-j9kg00qf 2652 13 of of IN cord-022526-j9kg00qf 2652 14 esophageal esophageal JJ cord-022526-j9kg00qf 2652 15 mucosal mucosal JJ cord-022526-j9kg00qf 2652 16 injury injury NN cord-022526-j9kg00qf 2652 17 . . . cord-022526-j9kg00qf 2653 1 One one PRP cord-022526-j9kg00qf 2653 2 should should MD cord-022526-j9kg00qf 2653 3 avoid avoid VB cord-022526-j9kg00qf 2653 4 orally orally RB cord-022526-j9kg00qf 2653 5 administered administer VBN cord-022526-j9kg00qf 2653 6 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 2653 7 if if IN cord-022526-j9kg00qf 2653 8 esophagitis esophagitis NN cord-022526-j9kg00qf 2653 9 is be VBZ cord-022526-j9kg00qf 2653 10 present present JJ cord-022526-j9kg00qf 2653 11 . . . cord-022526-j9kg00qf 2654 1 After after IN cord-022526-j9kg00qf 2654 2 48 48 CD cord-022526-j9kg00qf 2654 3 to to TO cord-022526-j9kg00qf 2654 4 72 72 CD cord-022526-j9kg00qf 2654 5 hours hour NNS cord-022526-j9kg00qf 2654 6 or or CC cord-022526-j9kg00qf 2654 7 when when WRB cord-022526-j9kg00qf 2654 8 the the DT cord-022526-j9kg00qf 2654 9 esophageal esophageal JJ cord-022526-j9kg00qf 2654 10 duodenal duodenal JJ cord-022526-j9kg00qf 2654 11 strictures stricture NNS cord-022526-j9kg00qf 2654 12 caused cause VBN cord-022526-j9kg00qf 2654 13 by by IN cord-022526-j9kg00qf 2654 14 chronic chronic JJ cord-022526-j9kg00qf 2654 15 ulceration ulceration NN cord-022526-j9kg00qf 2654 16 commonly commonly RB cord-022526-j9kg00qf 2654 17 have have VBP cord-022526-j9kg00qf 2654 18 reflux reflux NN cord-022526-j9kg00qf 2654 19 esophagitis esophagitis NN cord-022526-j9kg00qf 2654 20 . . . cord-022526-j9kg00qf 2655 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 2655 2 requires require VBZ cord-022526-j9kg00qf 2655 3 endoscopic endoscopic JJ cord-022526-j9kg00qf 2655 4 examination examination NN cord-022526-j9kg00qf 2655 5 of of IN cord-022526-j9kg00qf 2655 6 the the DT cord-022526-j9kg00qf 2655 7 esophagus esophagus NN cord-022526-j9kg00qf 2655 8 . . . cord-022526-j9kg00qf 2656 1 One one CD cord-022526-j9kg00qf 2656 2 may may MD cord-022526-j9kg00qf 2656 3 note note VB cord-022526-j9kg00qf 2656 4 diffuse diffuse JJ cord-022526-j9kg00qf 2656 5 , , , cord-022526-j9kg00qf 2656 6 patchy patchy JJ cord-022526-j9kg00qf 2656 7 , , , cord-022526-j9kg00qf 2656 8 linear linear JJ cord-022526-j9kg00qf 2656 9 , , , cord-022526-j9kg00qf 2656 10 or or CC cord-022526-j9kg00qf 2656 11 coalescing coalesce VBG cord-022526-j9kg00qf 2656 12 erosion erosion NN cord-022526-j9kg00qf 2656 13 or or CC cord-022526-j9kg00qf 2656 14 ulcerations ulceration NNS cord-022526-j9kg00qf 2656 15 ( ( -LRB- cord-022526-j9kg00qf 2656 16 see see VB cord-022526-j9kg00qf 2656 17 Figures figure NNS cord-022526-j9kg00qf 2656 18 13.9 13.9 CD cord-022526-j9kg00qf 2656 19 - - SYM cord-022526-j9kg00qf 2656 20 3 3 CD cord-022526-j9kg00qf 2656 21 and and CC cord-022526-j9kg00qf 2656 22 13.9 13.9 CD cord-022526-j9kg00qf 2656 23 - - SYM cord-022526-j9kg00qf 2656 24 4 4 CD cord-022526-j9kg00qf 2656 25 ) ) -RRB- cord-022526-j9kg00qf 2656 26 . . . cord-022526-j9kg00qf 2657 1 One one CD cord-022526-j9kg00qf 2657 2 also also RB cord-022526-j9kg00qf 2657 3 may may MD cord-022526-j9kg00qf 2657 4 observe observe VB cord-022526-j9kg00qf 2657 5 significant significant JJ cord-022526-j9kg00qf 2657 6 edema edema NN cord-022526-j9kg00qf 2657 7 or or CC cord-022526-j9kg00qf 2657 8 hyperemia hyperemia NN cord-022526-j9kg00qf 2657 9 . . . cord-022526-j9kg00qf 2658 1 Determining determine VBG cord-022526-j9kg00qf 2658 2 whether whether IN cord-022526-j9kg00qf 2658 3 an an DT cord-022526-j9kg00qf 2658 4 underlying underlie VBG cord-022526-j9kg00qf 2658 5 disease disease NN cord-022526-j9kg00qf 2658 6 , , , cord-022526-j9kg00qf 2658 7 such such JJ cord-022526-j9kg00qf 2658 8 as as IN cord-022526-j9kg00qf 2658 9 infection infection NN cord-022526-j9kg00qf 2658 10 , , , cord-022526-j9kg00qf 2658 11 neoplasia neoplasia NN cord-022526-j9kg00qf 2658 12 , , , cord-022526-j9kg00qf 2658 13 esophageal esophageal JJ cord-022526-j9kg00qf 2658 14 strictures stricture NNS cord-022526-j9kg00qf 2658 15 , , , cord-022526-j9kg00qf 2658 16 or or CC cord-022526-j9kg00qf 2658 17 diverticula diverticula NN cord-022526-j9kg00qf 2658 18 , , , cord-022526-j9kg00qf 2658 19 is be VBZ cord-022526-j9kg00qf 2658 20 present present JJ cord-022526-j9kg00qf 2658 21 is be VBZ cord-022526-j9kg00qf 2658 22 important important JJ cord-022526-j9kg00qf 2658 23 . . . cord-022526-j9kg00qf 2659 1 In in IN cord-022526-j9kg00qf 2659 2 addition addition NN cord-022526-j9kg00qf 2659 3 , , , cord-022526-j9kg00qf 2659 4 one one PRP cord-022526-j9kg00qf 2659 5 must must MD cord-022526-j9kg00qf 2659 6 examine examine VB cord-022526-j9kg00qf 2659 7 the the DT cord-022526-j9kg00qf 2659 8 stomach stomach NN cord-022526-j9kg00qf 2659 9 to to TO cord-022526-j9kg00qf 2659 10 determine determine VB cord-022526-j9kg00qf 2659 11 whether whether IN cord-022526-j9kg00qf 2659 12 the the DT cord-022526-j9kg00qf 2659 13 esophagitis esophagitis NN cord-022526-j9kg00qf 2659 14 is be VBZ cord-022526-j9kg00qf 2659 15 associated associate VBN cord-022526-j9kg00qf 2659 16 with with IN cord-022526-j9kg00qf 2659 17 gastritis gastritis NN cord-022526-j9kg00qf 2659 18 , , , cord-022526-j9kg00qf 2659 19 gastric gastric JJ cord-022526-j9kg00qf 2659 20 obstruction obstruction NN cord-022526-j9kg00qf 2659 21 , , , cord-022526-j9kg00qf 2659 22 or or CC cord-022526-j9kg00qf 2659 23 gastric gastric JJ cord-022526-j9kg00qf 2659 24 ulcer ulcer NN cord-022526-j9kg00qf 2659 25 disease disease NN cord-022526-j9kg00qf 2659 26 . . . cord-022526-j9kg00qf 2660 1 Contrast contrast NN cord-022526-j9kg00qf 2660 2 radiography radiography NN cord-022526-j9kg00qf 2660 3 may may MD cord-022526-j9kg00qf 2660 4 be be VB cord-022526-j9kg00qf 2660 5 helpful helpful JJ cord-022526-j9kg00qf 2660 6 to to TO cord-022526-j9kg00qf 2660 7 detect detect VB cord-022526-j9kg00qf 2660 8 esophageal esophageal JJ cord-022526-j9kg00qf 2660 9 ulceration ulceration NN cord-022526-j9kg00qf 2660 10 and and CC cord-022526-j9kg00qf 2660 11 is be VBZ cord-022526-j9kg00qf 2660 12 useful useful JJ cord-022526-j9kg00qf 2660 13 to to TO cord-022526-j9kg00qf 2660 14 assess assess VB cord-022526-j9kg00qf 2660 15 esophageal esophageal JJ cord-022526-j9kg00qf 2660 16 motility motility NN cord-022526-j9kg00qf 2660 17 and and CC cord-022526-j9kg00qf 2660 18 transit transit NN cord-022526-j9kg00qf 2660 19 time time NN cord-022526-j9kg00qf 2660 20 . . . cord-022526-j9kg00qf 2661 1 14 14 CD cord-022526-j9kg00qf 2661 2 _SP cord-022526-j9kg00qf 2662 1 The the DT cord-022526-j9kg00qf 2662 2 principles principle NNS cord-022526-j9kg00qf 2662 3 of of IN cord-022526-j9kg00qf 2662 4 therapy therapy NN cord-022526-j9kg00qf 2662 5 for for IN cord-022526-j9kg00qf 2662 6 reflux reflux NN cord-022526-j9kg00qf 2662 7 esophagitis esophagitis NN cord-022526-j9kg00qf 2662 8 include include VBP cord-022526-j9kg00qf 2662 9 control control NN cord-022526-j9kg00qf 2662 10 of of IN cord-022526-j9kg00qf 2662 11 gastric gastric JJ cord-022526-j9kg00qf 2662 12 acidity acidity NN cord-022526-j9kg00qf 2662 13 , , , cord-022526-j9kg00qf 2662 14 mucosal mucosal JJ cord-022526-j9kg00qf 2662 15 protection protection NN cord-022526-j9kg00qf 2662 16 , , , cord-022526-j9kg00qf 2662 17 and and CC cord-022526-j9kg00qf 2662 18 correction correction NN cord-022526-j9kg00qf 2662 19 of of IN cord-022526-j9kg00qf 2662 20 any any DT cord-022526-j9kg00qf 2662 21 underlying underlying JJ cord-022526-j9kg00qf 2662 22 disorder disorder NN cord-022526-j9kg00qf 2662 23 contributing contribute VBG cord-022526-j9kg00qf 2662 24 to to IN cord-022526-j9kg00qf 2662 25 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2662 26 reflux reflux NN cord-022526-j9kg00qf 2662 27 . . . cord-022526-j9kg00qf 2663 1 Reduction reduction NN cord-022526-j9kg00qf 2663 2 of of IN cord-022526-j9kg00qf 2663 3 gastric gastric JJ cord-022526-j9kg00qf 2663 4 acid acid NN cord-022526-j9kg00qf 2663 5 production production NN cord-022526-j9kg00qf 2663 6 with with IN cord-022526-j9kg00qf 2663 7 H h NN cord-022526-j9kg00qf 2663 8 2 2 CD cord-022526-j9kg00qf 2663 9 histamine histamine NN cord-022526-j9kg00qf 2663 10 receptor receptor NN cord-022526-j9kg00qf 2663 11 blockers blocker NNS cord-022526-j9kg00qf 2663 12 such such JJ cord-022526-j9kg00qf 2663 13 as as IN cord-022526-j9kg00qf 2663 14 ranitidine ranitidine NN cord-022526-j9kg00qf 2663 15 or or CC cord-022526-j9kg00qf 2663 16 proton proton NN cord-022526-j9kg00qf 2663 17 pump pump NN cord-022526-j9kg00qf 2663 18 antagonists antagonist NNS cord-022526-j9kg00qf 2663 19 such such JJ cord-022526-j9kg00qf 2663 20 as as IN cord-022526-j9kg00qf 2663 21 omeprazole omeprazole NN cord-022526-j9kg00qf 2663 22 is be VBZ cord-022526-j9kg00qf 2663 23 critical critical JJ cord-022526-j9kg00qf 2663 24 for for IN cord-022526-j9kg00qf 2663 25 resolution resolution NN cord-022526-j9kg00qf 2663 26 of of IN cord-022526-j9kg00qf 2663 27 the the DT cord-022526-j9kg00qf 2663 28 esophagitis esophagitis NN cord-022526-j9kg00qf 2663 29 . . . cord-022526-j9kg00qf 2664 1 Some some DT cord-022526-j9kg00qf 2664 2 clinicians clinician NNS cord-022526-j9kg00qf 2664 3 advocate advocate VBP cord-022526-j9kg00qf 2664 4 using use VBG cord-022526-j9kg00qf 2664 5 sucralfate sucralfate NNP cord-022526-j9kg00qf 2664 6 to to TO cord-022526-j9kg00qf 2664 7 promote promote VB cord-022526-j9kg00qf 2664 8 healing healing NN cord-022526-j9kg00qf 2664 9 of of IN cord-022526-j9kg00qf 2664 10 ulcerated ulcerated JJ cord-022526-j9kg00qf 2664 11 esophageal esophageal JJ cord-022526-j9kg00qf 2664 12 mucosa mucosa NN cord-022526-j9kg00qf 2664 13 . . . cord-022526-j9kg00qf 2665 1 However however RB cord-022526-j9kg00qf 2665 2 , , , cord-022526-j9kg00qf 2665 3 the the DT cord-022526-j9kg00qf 2665 4 ability ability NN cord-022526-j9kg00qf 2665 5 of of IN cord-022526-j9kg00qf 2665 6 sucralfate sucralfate NN cord-022526-j9kg00qf 2665 7 to to TO cord-022526-j9kg00qf 2665 8 bind bind VB cord-022526-j9kg00qf 2665 9 ulcerated ulcerated JJ cord-022526-j9kg00qf 2665 10 esophageal esophageal JJ cord-022526-j9kg00qf 2665 11 mucosa mucosa NN cord-022526-j9kg00qf 2665 12 is be VBZ cord-022526-j9kg00qf 2665 13 not not RB cord-022526-j9kg00qf 2665 14 proven prove VBN cord-022526-j9kg00qf 2665 15 , , , cord-022526-j9kg00qf 2665 16 nor nor CC cord-022526-j9kg00qf 2665 17 is be VBZ cord-022526-j9kg00qf 2665 18 the the DT cord-022526-j9kg00qf 2665 19 efficacy efficacy NN cord-022526-j9kg00qf 2665 20 of of IN cord-022526-j9kg00qf 2665 21 sucralfate sucralfate NNP cord-022526-j9kg00qf 2665 22 for for IN cord-022526-j9kg00qf 2665 23 hastening hasten VBG cord-022526-j9kg00qf 2665 24 esophageal esophageal JJ cord-022526-j9kg00qf 2665 25 ulcer ulcer NN cord-022526-j9kg00qf 2665 26 healing healing NN cord-022526-j9kg00qf 2665 27 . . . cord-022526-j9kg00qf 2666 1 Horses horse NNS cord-022526-j9kg00qf 2666 2 with with IN cord-022526-j9kg00qf 2666 3 reflux reflux NN cord-022526-j9kg00qf 2666 4 esophagitis esophagitis NN cord-022526-j9kg00qf 2666 5 following follow VBG cord-022526-j9kg00qf 2666 6 delayed delay VBN cord-022526-j9kg00qf 2666 7 gastric gastric JJ cord-022526-j9kg00qf 2666 8 outflow outflow NN cord-022526-j9kg00qf 2666 9 caused cause VBN cord-022526-j9kg00qf 2666 10 by by IN cord-022526-j9kg00qf 2666 11 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 2666 12 ulcer ulcer NN cord-022526-j9kg00qf 2666 13 disease disease NN cord-022526-j9kg00qf 2666 14 , , , cord-022526-j9kg00qf 2666 15 gastric gastric JJ cord-022526-j9kg00qf 2666 16 paresis paresis NN cord-022526-j9kg00qf 2666 17 , , , cord-022526-j9kg00qf 2666 18 or or CC cord-022526-j9kg00qf 2666 19 proximal proximal JJ cord-022526-j9kg00qf 2666 20 enteritis enteritis NN cord-022526-j9kg00qf 2666 21 may may MD cord-022526-j9kg00qf 2666 22 benefit benefit VB cord-022526-j9kg00qf 2666 23 from from IN cord-022526-j9kg00qf 2666 24 prokinetic prokinetic JJ cord-022526-j9kg00qf 2666 25 drugs drug NNS cord-022526-j9kg00qf 2666 26 that that WDT cord-022526-j9kg00qf 2666 27 act act VBP cord-022526-j9kg00qf 2666 28 on on IN cord-022526-j9kg00qf 2666 29 the the DT cord-022526-j9kg00qf 2666 30 proximal proximal JJ cord-022526-j9kg00qf 2666 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2666 32 tract tract NN cord-022526-j9kg00qf 2666 33 . . . cord-022526-j9kg00qf 2667 1 Metoclopramide Metoclopramide NNP cord-022526-j9kg00qf 2667 2 ( ( -LRB- cord-022526-j9kg00qf 2667 3 0.02 0.02 CD cord-022526-j9kg00qf 2667 4 to to IN cord-022526-j9kg00qf 2667 5 0.1 0.1 CD cord-022526-j9kg00qf 2667 6 mg mg NNP cord-022526-j9kg00qf 2667 7 / / SYM cord-022526-j9kg00qf 2667 8 kg kg XX cord-022526-j9kg00qf 2667 9 subcutaneously subcutaneously RB cord-022526-j9kg00qf 2667 10 every every DT cord-022526-j9kg00qf 2667 11 4 4 CD cord-022526-j9kg00qf 2667 12 to to TO cord-022526-j9kg00qf 2667 13 12 12 CD cord-022526-j9kg00qf 2667 14 hours hour NNS cord-022526-j9kg00qf 2667 15 ) ) -RRB- cord-022526-j9kg00qf 2667 16 reduces reduce VBZ cord-022526-j9kg00qf 2667 17 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2667 18 reflux reflux NN cord-022526-j9kg00qf 2667 19 by by IN cord-022526-j9kg00qf 2667 20 increasing increase VBG cord-022526-j9kg00qf 2667 21 lower low JJR cord-022526-j9kg00qf 2667 22 esophageal esophageal JJ cord-022526-j9kg00qf 2667 23 sphincter sphincter NN cord-022526-j9kg00qf 2667 24 tone tone NN cord-022526-j9kg00qf 2667 25 , , , cord-022526-j9kg00qf 2667 26 gastric gastric JJ cord-022526-j9kg00qf 2667 27 emptying emptying NN cord-022526-j9kg00qf 2667 28 , , , cord-022526-j9kg00qf 2667 29 and and CC cord-022526-j9kg00qf 2667 30 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 2667 31 coordination coordination NN cord-022526-j9kg00qf 2667 32 . . . cord-022526-j9kg00qf 2668 1 One one PRP cord-022526-j9kg00qf 2668 2 should should MD cord-022526-j9kg00qf 2668 3 exercise exercise VB cord-022526-j9kg00qf 2668 4 caution caution NN cord-022526-j9kg00qf 2668 5 when when WRB cord-022526-j9kg00qf 2668 6 giving give VBG cord-022526-j9kg00qf 2668 7 metoclopramide metoclopramide NN cord-022526-j9kg00qf 2668 8 to to IN cord-022526-j9kg00qf 2668 9 horses horse NNS cord-022526-j9kg00qf 2668 10 because because IN cord-022526-j9kg00qf 2668 11 they -PRON- PRP cord-022526-j9kg00qf 2668 12 are be VBP cord-022526-j9kg00qf 2668 13 prone prone JJ cord-022526-j9kg00qf 2668 14 to to IN cord-022526-j9kg00qf 2668 15 extrapyramidal extrapyramidal JJ cord-022526-j9kg00qf 2668 16 neurologic neurologic JJ cord-022526-j9kg00qf 2668 17 side side JJ cord-022526-j9kg00qf 2668 18 effects effect NNS cord-022526-j9kg00qf 2668 19 of of IN cord-022526-j9kg00qf 2668 20 the the DT cord-022526-j9kg00qf 2668 21 drug drug NN cord-022526-j9kg00qf 2668 22 . . . cord-022526-j9kg00qf 2669 1 Cholinergic cholinergic JJ cord-022526-j9kg00qf 2669 2 drugs drug NNS cord-022526-j9kg00qf 2669 3 such such JJ cord-022526-j9kg00qf 2669 4 as as IN cord-022526-j9kg00qf 2669 5 bethanechol bethanechol NNP cord-022526-j9kg00qf 2669 6 ( ( -LRB- cord-022526-j9kg00qf 2669 7 0.025 0.025 CD cord-022526-j9kg00qf 2669 8 to to IN cord-022526-j9kg00qf 2669 9 0.035 0.035 CD cord-022526-j9kg00qf 2669 10 mg mg NNP cord-022526-j9kg00qf 2669 11 / / SYM cord-022526-j9kg00qf 2669 12 kg kg NNP cord-022526-j9kg00qf 2669 13 subcutaneously subcutaneously RB cord-022526-j9kg00qf 2669 14 every every DT cord-022526-j9kg00qf 2669 15 4 4 CD cord-022526-j9kg00qf 2669 16 to to TO cord-022526-j9kg00qf 2669 17 24 24 CD cord-022526-j9kg00qf 2669 18 hours hour NNS cord-022526-j9kg00qf 2669 19 or or CC cord-022526-j9kg00qf 2669 20 0.035 0.035 CD cord-022526-j9kg00qf 2669 21 to to IN cord-022526-j9kg00qf 2670 1 0.045 0.045 CD cord-022526-j9kg00qf 2670 2 mg mg NNP cord-022526-j9kg00qf 2670 3 / / SYM cord-022526-j9kg00qf 2670 4 kg kg VBZ cord-022526-j9kg00qf 2670 5 orally orally RB cord-022526-j9kg00qf 2670 6 every every DT cord-022526-j9kg00qf 2670 7 6 6 CD cord-022526-j9kg00qf 2670 8 to to TO cord-022526-j9kg00qf 2670 9 8 8 CD cord-022526-j9kg00qf 2670 10 hours hour NNS cord-022526-j9kg00qf 2670 11 ) ) -RRB- cord-022526-j9kg00qf 2670 12 may may MD cord-022526-j9kg00qf 2670 13 improve improve VB cord-022526-j9kg00qf 2670 14 gastric gastric JJ cord-022526-j9kg00qf 2670 15 emptying emptying NN cord-022526-j9kg00qf 2670 16 and and CC cord-022526-j9kg00qf 2670 17 are be VBP cord-022526-j9kg00qf 2670 18 effective effective JJ cord-022526-j9kg00qf 2670 19 for for IN cord-022526-j9kg00qf 2670 20 treating treat VBG cord-022526-j9kg00qf 2670 21 reflux reflux NN cord-022526-j9kg00qf 2670 22 esophagitis esophagitis NN cord-022526-j9kg00qf 2670 23 . . . cord-022526-j9kg00qf 2671 1 For for IN cord-022526-j9kg00qf 2671 2 esophagitis esophagitis NN cord-022526-j9kg00qf 2671 3 from from IN cord-022526-j9kg00qf 2671 4 trauma trauma NN cord-022526-j9kg00qf 2671 5 or or CC cord-022526-j9kg00qf 2671 6 pressure pressure NN cord-022526-j9kg00qf 2671 7 injury injury NN cord-022526-j9kg00qf 2671 8 after after IN cord-022526-j9kg00qf 2671 9 esophageal esophageal JJ cord-022526-j9kg00qf 2671 10 impaction impaction NN cord-022526-j9kg00qf 2671 11 , , , cord-022526-j9kg00qf 2671 12 judicious judicious JJ cord-022526-j9kg00qf 2671 13 use use NN cord-022526-j9kg00qf 2671 14 of of IN cord-022526-j9kg00qf 2671 15 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 2671 16 may may MD cord-022526-j9kg00qf 2671 17 be be VB cord-022526-j9kg00qf 2671 18 warranted warrant VBN cord-022526-j9kg00qf 2671 19 to to TO cord-022526-j9kg00qf 2671 20 reduce reduce VB cord-022526-j9kg00qf 2671 21 esophageal esophageal JJ cord-022526-j9kg00qf 2671 22 inflammation inflammation NN cord-022526-j9kg00qf 2671 23 and and CC cord-022526-j9kg00qf 2671 24 pain pain NN cord-022526-j9kg00qf 2671 25 . . . cord-022526-j9kg00qf 2672 1 Dietary dietary JJ cord-022526-j9kg00qf 2672 2 modification modification NN cord-022526-j9kg00qf 2672 3 may may MD cord-022526-j9kg00qf 2672 4 be be VB cord-022526-j9kg00qf 2672 5 necessary necessary JJ cord-022526-j9kg00qf 2672 6 for for IN cord-022526-j9kg00qf 2672 7 patients patient NNS cord-022526-j9kg00qf 2672 8 with with IN cord-022526-j9kg00qf 2672 9 esophagitis esophagitis NN cord-022526-j9kg00qf 2672 10 , , , cord-022526-j9kg00qf 2672 11 depending depend VBG cord-022526-j9kg00qf 2672 12 on on IN cord-022526-j9kg00qf 2672 13 the the DT cord-022526-j9kg00qf 2672 14 degree degree NN cord-022526-j9kg00qf 2672 15 of of IN cord-022526-j9kg00qf 2672 16 ulceration ulceration NN cord-022526-j9kg00qf 2672 17 or or CC cord-022526-j9kg00qf 2672 18 if if IN cord-022526-j9kg00qf 2672 19 motility motility NN cord-022526-j9kg00qf 2672 20 is be VBZ cord-022526-j9kg00qf 2672 21 impaired impair VBN cord-022526-j9kg00qf 2672 22 . . . cord-022526-j9kg00qf 2673 1 One one PRP cord-022526-j9kg00qf 2673 2 should should MD cord-022526-j9kg00qf 2673 3 feed feed VB cord-022526-j9kg00qf 2673 4 horses horse NNS cord-022526-j9kg00qf 2673 5 with with IN cord-022526-j9kg00qf 2673 6 mild mild JJ cord-022526-j9kg00qf 2673 7 esophagitis esophagitis JJ cord-022526-j9kg00qf 2673 8 frequent frequent JJ cord-022526-j9kg00qf 2673 9 small small JJ cord-022526-j9kg00qf 2673 10 meals meal NNS cord-022526-j9kg00qf 2673 11 of of IN cord-022526-j9kg00qf 2673 12 moistened moistened JJ cord-022526-j9kg00qf 2673 13 pellets pellet NNS cord-022526-j9kg00qf 2673 14 and and CC cord-022526-j9kg00qf 2673 15 fresh fresh JJ cord-022526-j9kg00qf 2673 16 grass grass NN cord-022526-j9kg00qf 2673 17 . . . cord-022526-j9kg00qf 2674 1 Severe severe JJ cord-022526-j9kg00qf 2674 2 esophagitis esophagitis NN cord-022526-j9kg00qf 2674 3 may may MD cord-022526-j9kg00qf 2674 4 necessitate necessitate VB cord-022526-j9kg00qf 2674 5 withholding withhold VBG cord-022526-j9kg00qf 2674 6 food food NN cord-022526-j9kg00qf 2674 7 and and CC cord-022526-j9kg00qf 2674 8 complete complete VB cord-022526-j9kg00qf 2674 9 esophageal esophageal JJ cord-022526-j9kg00qf 2674 10 rest rest NN cord-022526-j9kg00qf 2674 11 for for IN cord-022526-j9kg00qf 2674 12 several several JJ cord-022526-j9kg00qf 2674 13 days day NNS cord-022526-j9kg00qf 2674 14 . . . cord-022526-j9kg00qf 2675 1 Although although IN cord-022526-j9kg00qf 2675 2 the the DT cord-022526-j9kg00qf 2675 3 prognosis prognosis NN cord-022526-j9kg00qf 2675 4 for for IN cord-022526-j9kg00qf 2675 5 esophagitis esophagitis NN cord-022526-j9kg00qf 2675 6 is be VBZ cord-022526-j9kg00qf 2675 7 good good JJ cord-022526-j9kg00qf 2675 8 in in IN cord-022526-j9kg00qf 2675 9 the the DT cord-022526-j9kg00qf 2675 10 absence absence NN cord-022526-j9kg00qf 2675 11 of of IN cord-022526-j9kg00qf 2675 12 underlying underlie VBG cord-022526-j9kg00qf 2675 13 disease disease NN cord-022526-j9kg00qf 2675 14 , , , cord-022526-j9kg00qf 2675 15 the the DT cord-022526-j9kg00qf 2675 16 risk risk NN cord-022526-j9kg00qf 2675 17 of of IN cord-022526-j9kg00qf 2675 18 esophagus esophagus NN cord-022526-j9kg00qf 2675 19 is be VBZ cord-022526-j9kg00qf 2675 20 delayed delay VBN cord-022526-j9kg00qf 2675 21 , , , cord-022526-j9kg00qf 2675 22 such such JJ cord-022526-j9kg00qf 2675 23 as as IN cord-022526-j9kg00qf 2675 24 in in IN cord-022526-j9kg00qf 2675 25 functional functional JJ cord-022526-j9kg00qf 2675 26 disorders disorder NNS cord-022526-j9kg00qf 2675 27 of of IN cord-022526-j9kg00qf 2675 28 the the DT cord-022526-j9kg00qf 2675 29 esophagus esophagus NN cord-022526-j9kg00qf 2675 30 . . . cord-022526-j9kg00qf 2676 1 Like like IN cord-022526-j9kg00qf 2676 2 ulceration ulceration NN cord-022526-j9kg00qf 2676 3 of of IN cord-022526-j9kg00qf 2676 4 the the DT cord-022526-j9kg00qf 2676 5 squamous squamous JJ cord-022526-j9kg00qf 2676 6 portion portion NN cord-022526-j9kg00qf 2676 7 of of IN cord-022526-j9kg00qf 2676 8 the the DT cord-022526-j9kg00qf 2676 9 stomach stomach NN cord-022526-j9kg00qf 2676 10 in in IN cord-022526-j9kg00qf 2676 11 horses horse NNS cord-022526-j9kg00qf 2676 12 , , , cord-022526-j9kg00qf 2676 13 gastric gastric JJ cord-022526-j9kg00qf 2676 14 acid acid NN cord-022526-j9kg00qf 2676 15 and and CC cord-022526-j9kg00qf 2676 16 bile bile NN cord-022526-j9kg00qf 2676 17 salt salt NN cord-022526-j9kg00qf 2676 18 chemical chemical NN cord-022526-j9kg00qf 2676 19 injury injury NN cord-022526-j9kg00qf 2676 20 is be VBZ cord-022526-j9kg00qf 2676 21 a a DT cord-022526-j9kg00qf 2676 22 major major JJ cord-022526-j9kg00qf 2676 23 mechanism mechanism NN cord-022526-j9kg00qf 2676 24 of of IN cord-022526-j9kg00qf 2676 25 esophageal esophageal JJ cord-022526-j9kg00qf 2676 26 squamous squamous JJ cord-022526-j9kg00qf 2676 27 epithelial epithelial JJ cord-022526-j9kg00qf 2676 28 ulceration ulceration NN cord-022526-j9kg00qf 2676 29 . . . cord-022526-j9kg00qf 2677 1 22 22 CD cord-022526-j9kg00qf 2677 2 , , , cord-022526-j9kg00qf 2677 3 23 23 CD cord-022526-j9kg00qf 2677 4 Reflux reflux NN cord-022526-j9kg00qf 2677 5 esophagitis esophagitis NN cord-022526-j9kg00qf 2677 6 may may MD cord-022526-j9kg00qf 2677 7 occur occur VB cord-022526-j9kg00qf 2677 8 along along IN cord-022526-j9kg00qf 2677 9 with with IN cord-022526-j9kg00qf 2677 10 gastric gastric JJ cord-022526-j9kg00qf 2677 11 ulcer ulcer NN cord-022526-j9kg00qf 2677 12 disease disease NN cord-022526-j9kg00qf 2677 13 , , , cord-022526-j9kg00qf 2677 14 motility motility NN cord-022526-j9kg00qf 2677 15 disorders disorder NNS cord-022526-j9kg00qf 2677 16 , , , cord-022526-j9kg00qf 2677 17 increased increase VBD cord-022526-j9kg00qf 2677 18 gastric gastric JJ cord-022526-j9kg00qf 2677 19 volume volume NN cord-022526-j9kg00qf 2677 20 from from IN cord-022526-j9kg00qf 2677 21 gastric gastric JJ cord-022526-j9kg00qf 2677 22 outflow outflow NN cord-022526-j9kg00qf 2677 23 obstructions obstruction NNS cord-022526-j9kg00qf 2677 24 , , , cord-022526-j9kg00qf 2677 25 gastric gastric JJ cord-022526-j9kg00qf 2677 26 paresis paresis NN cord-022526-j9kg00qf 2677 27 , , , cord-022526-j9kg00qf 2677 28 intestinal intestinal JJ cord-022526-j9kg00qf 2677 29 ileus ileus NN cord-022526-j9kg00qf 2677 30 , , , cord-022526-j9kg00qf 2677 31 or or CC cord-022526-j9kg00qf 2677 32 impaired impair VBN cord-022526-j9kg00qf 2677 33 lower low JJR cord-022526-j9kg00qf 2677 34 esophageal esophageal JJ cord-022526-j9kg00qf 2677 35 sphincter sphincter NN cord-022526-j9kg00qf 2677 36 function function NN cord-022526-j9kg00qf 2677 37 . . . cord-022526-j9kg00qf 2678 1 7 7 CD cord-022526-j9kg00qf 2678 2 , , , cord-022526-j9kg00qf 2678 3 22 22 CD cord-022526-j9kg00qf 2678 4 Other other JJ cord-022526-j9kg00qf 2678 5 causes cause NNS cord-022526-j9kg00qf 2678 6 of of IN cord-022526-j9kg00qf 2678 7 esophagitis esophagitis NN cord-022526-j9kg00qf 2678 8 in in IN cord-022526-j9kg00qf 2678 9 horses horse NNS cord-022526-j9kg00qf 2678 10 include include VBP cord-022526-j9kg00qf 2678 11 trauma trauma NN cord-022526-j9kg00qf 2678 12 ( ( -LRB- cord-022526-j9kg00qf 2678 13 foreign foreign JJ cord-022526-j9kg00qf 2678 14 bodies body NNS cord-022526-j9kg00qf 2678 15 , , , cord-022526-j9kg00qf 2678 16 food food NN cord-022526-j9kg00qf 2678 17 impactions impaction NNS cord-022526-j9kg00qf 2678 18 , , , cord-022526-j9kg00qf 2678 19 nasogastric nasogastric NN cord-022526-j9kg00qf 2678 20 tubes tube NNS cord-022526-j9kg00qf 2678 21 ) ) -RRB- cord-022526-j9kg00qf 2678 22 , , , cord-022526-j9kg00qf 2678 23 infection infection NN cord-022526-j9kg00qf 2678 24 ( ( -LRB- cord-022526-j9kg00qf 2678 25 mural mural NN cord-022526-j9kg00qf 2678 26 abscesses abscess NNS cord-022526-j9kg00qf 2678 27 ) ) -RRB- cord-022526-j9kg00qf 2678 28 , , , cord-022526-j9kg00qf 2678 29 or or CC cord-022526-j9kg00qf 2678 30 chemical chemical JJ cord-022526-j9kg00qf 2678 31 injury injury NN cord-022526-j9kg00qf 2678 32 ( ( -LRB- cord-022526-j9kg00qf 2678 33 pharmaceuticals pharmaceutical NNS cord-022526-j9kg00qf 2678 34 , , , cord-022526-j9kg00qf 2678 35 cantharidin cantharidin NNP cord-022526-j9kg00qf 2678 36 ) ) -RRB- cord-022526-j9kg00qf 2679 1 ( ( -LRB- cord-022526-j9kg00qf 2679 2 Figure figure NN cord-022526-j9kg00qf 2679 3 13 13 CD cord-022526-j9kg00qf 2679 4 .9 .9 CD cord-022526-j9kg00qf 2679 5 - - SYM cord-022526-j9kg00qf 2679 6 4 4 CD cord-022526-j9kg00qf 2679 7 ) ) -RRB- cord-022526-j9kg00qf 2679 8 . . . cord-022526-j9kg00qf 2680 1 [ [ -LRB- cord-022526-j9kg00qf 2680 2 24 24 CD cord-022526-j9kg00qf 2680 3 ] ] -RRB- cord-022526-j9kg00qf 2680 4 [ [ -LRB- cord-022526-j9kg00qf 2680 5 25 25 CD cord-022526-j9kg00qf 2680 6 ] ] -RRB- cord-022526-j9kg00qf 2680 7 [ [ -LRB- cord-022526-j9kg00qf 2680 8 26 26 CD cord-022526-j9kg00qf 2680 9 ] ] -RRB- cord-022526-j9kg00qf 2680 10 [ [ -LRB- cord-022526-j9kg00qf 2680 11 27 27 CD cord-022526-j9kg00qf 2680 12 ] ] -RRB- cord-022526-j9kg00qf 2680 13 _SP cord-022526-j9kg00qf 2681 1 The the DT cord-022526-j9kg00qf 2681 2 clinical clinical JJ cord-022526-j9kg00qf 2681 3 signs sign NNS cord-022526-j9kg00qf 2681 4 of of IN cord-022526-j9kg00qf 2681 5 esophagitis esophagitis NN cord-022526-j9kg00qf 2681 6 are be VBP cord-022526-j9kg00qf 2681 7 nonspecific nonspecific JJ cord-022526-j9kg00qf 2681 8 and and CC cord-022526-j9kg00qf 2681 9 similar similar JJ cord-022526-j9kg00qf 2681 10 to to IN cord-022526-j9kg00qf 2681 11 esophageal esophageal JJ cord-022526-j9kg00qf 2681 12 obstruction obstruction NN cord-022526-j9kg00qf 2681 13 and and CC cord-022526-j9kg00qf 2681 14 gastric gastric JJ cord-022526-j9kg00qf 2681 15 ulcer ulcer NN cord-022526-j9kg00qf 2681 16 diseases disease NNS cord-022526-j9kg00qf 2681 17 . . . cord-022526-j9kg00qf 2682 1 Gagging gagging NN cord-022526-j9kg00qf 2682 2 or or CC cord-022526-j9kg00qf 2682 3 discomfort discomfort NN cord-022526-j9kg00qf 2682 4 when when WRB cord-022526-j9kg00qf 2682 5 swallowing swallowing NN cord-022526-j9kg00qf 2682 6 may may MD cord-022526-j9kg00qf 2682 7 be be VB cord-022526-j9kg00qf 2682 8 evident evident JJ cord-022526-j9kg00qf 2682 9 , , , cord-022526-j9kg00qf 2682 10 and and CC cord-022526-j9kg00qf 2682 11 hypersalivation hypersalivation NN cord-022526-j9kg00qf 2682 12 and and CC cord-022526-j9kg00qf 2682 13 bruxism bruxism NN cord-022526-j9kg00qf 2682 14 are be VBP cord-022526-j9kg00qf 2682 15 signs sign NNS cord-022526-j9kg00qf 2682 16 of of IN cord-022526-j9kg00qf 2682 17 esophageal esophageal JJ cord-022526-j9kg00qf 2682 18 pain pain NN cord-022526-j9kg00qf 2682 19 . . . cord-022526-j9kg00qf 2683 1 Esophageal esophageal NN cord-022526-j9kg00qf 2684 1 ( ( -LRB- cord-022526-j9kg00qf 2684 2 postpharyngeal postpharyngeal NNP cord-022526-j9kg00qf 2684 3 ) ) -RRB- cord-022526-j9kg00qf 2684 4 dysphagia dysphagia NNP cord-022526-j9kg00qf 2684 5 may may MD cord-022526-j9kg00qf 2684 6 be be VB cord-022526-j9kg00qf 2684 7 evident evident JJ cord-022526-j9kg00qf 2684 8 . . . cord-022526-j9kg00qf 2685 1 One one CD cord-022526-j9kg00qf 2685 2 may may MD cord-022526-j9kg00qf 2685 3 note note VB cord-022526-j9kg00qf 2685 4 partial partial JJ cord-022526-j9kg00qf 2685 5 or or CC cord-022526-j9kg00qf 2685 6 complete complete JJ cord-022526-j9kg00qf 2685 7 anorexia anorexia NN cord-022526-j9kg00qf 2685 8 such such JJ cord-022526-j9kg00qf 2685 9 that that IN cord-022526-j9kg00qf 2685 10 horses horse NNS cord-022526-j9kg00qf 2685 11 with with IN cord-022526-j9kg00qf 2685 12 chronic chronic JJ cord-022526-j9kg00qf 2685 13 esophagitis esophagitis NN cord-022526-j9kg00qf 2685 14 may may MD cord-022526-j9kg00qf 2685 15 have have VB cord-022526-j9kg00qf 2685 16 significant significant JJ cord-022526-j9kg00qf 2685 17 weight weight NN cord-022526-j9kg00qf 2685 18 loss loss NN cord-022526-j9kg00qf 2685 19 . . . cord-022526-j9kg00qf 2686 1 Esophageal esophageal JJ cord-022526-j9kg00qf 2686 2 hypomotility hypomotility NN cord-022526-j9kg00qf 2686 3 dysfunction dysfunction NN cord-022526-j9kg00qf 2686 4 caused cause VBN cord-022526-j9kg00qf 2686 5 by by IN cord-022526-j9kg00qf 2686 6 the the DT cord-022526-j9kg00qf 2686 7 inflammatory inflammatory JJ cord-022526-j9kg00qf 2686 8 process process NN cord-022526-j9kg00qf 2686 9 may may MD cord-022526-j9kg00qf 2686 10 result result VB cord-022526-j9kg00qf 2686 11 in in IN cord-022526-j9kg00qf 2686 12 esophageal esophageal JJ cord-022526-j9kg00qf 2686 13 impaction impaction NN cord-022526-j9kg00qf 2686 14 . . . cord-022526-j9kg00qf 2687 1 Clinical clinical JJ cord-022526-j9kg00qf 2687 2 signs sign NNS cord-022526-j9kg00qf 2687 3 of of IN cord-022526-j9kg00qf 2687 4 underlying underlie VBG cord-022526-j9kg00qf 2687 5 diseases disease NNS cord-022526-j9kg00qf 2687 6 that that WDT cord-022526-j9kg00qf 2687 7 predispose predispose VBP cord-022526-j9kg00qf 2687 8 to to TO cord-022526-j9kg00qf 2687 9 esophagitis esophagitis NN cord-022526-j9kg00qf 2687 10 may may MD cord-022526-j9kg00qf 2687 11 predominate predominate VB cord-022526-j9kg00qf 2687 12 or or CC cord-022526-j9kg00qf 2687 13 mask mask VB cord-022526-j9kg00qf 2687 14 the the DT cord-022526-j9kg00qf 2687 15 signs sign NNS cord-022526-j9kg00qf 2687 16 of of IN cord-022526-j9kg00qf 2687 17 esophagitis esophagitis NN cord-022526-j9kg00qf 2687 18 . . . cord-022526-j9kg00qf 2688 1 Horses horse NNS cord-022526-j9kg00qf 2688 2 with with IN cord-022526-j9kg00qf 2688 3 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2688 4 motility motility NN cord-022526-j9kg00qf 2688 5 disorders disorder NNS cord-022526-j9kg00qf 2688 6 such such JJ cord-022526-j9kg00qf 2688 7 as as IN cord-022526-j9kg00qf 2688 8 proximal proximal JJ cord-022526-j9kg00qf 2688 9 enteritis enteritis NN cord-022526-j9kg00qf 2688 10 or or CC cord-022526-j9kg00qf 2688 11 gastric gastric JJ cord-022526-j9kg00qf 2688 12 outflow outflow JJ cord-022526-j9kg00qf 2688 13 obstruction obstruction NN cord-022526-j9kg00qf 2688 14 are be VBP cord-022526-j9kg00qf 2688 15 at at IN cord-022526-j9kg00qf 2688 16 a a DT cord-022526-j9kg00qf 2688 17 high high JJ cord-022526-j9kg00qf 2688 18 risk risk NN cord-022526-j9kg00qf 2688 19 of of IN cord-022526-j9kg00qf 2688 20 developing develop VBG cord-022526-j9kg00qf 2688 21 reflux reflux NN cord-022526-j9kg00qf 2688 22 esophagitis esophagitis NN cord-022526-j9kg00qf 2688 23 because because IN cord-022526-j9kg00qf 2688 24 of of IN cord-022526-j9kg00qf 2688 25 the the DT cord-022526-j9kg00qf 2688 26 presence presence NN cord-022526-j9kg00qf 2688 27 of of IN cord-022526-j9kg00qf 2688 28 gastric gastric JJ cord-022526-j9kg00qf 2688 29 acid acid NN cord-022526-j9kg00qf 2688 30 and and CC cord-022526-j9kg00qf 2688 31 bile bile NN cord-022526-j9kg00qf 2688 32 salts salt NNS cord-022526-j9kg00qf 2688 33 in in IN cord-022526-j9kg00qf 2688 34 the the DT cord-022526-j9kg00qf 2688 35 fluid fluid JJ cord-022526-j9kg00qf 2688 36 reflux reflux NN cord-022526-j9kg00qf 2688 37 . . . cord-022526-j9kg00qf 2689 1 Foals foal NNS cord-022526-j9kg00qf 2689 2 with with IN cord-022526-j9kg00qf 2689 3 gastric gastric JJ cord-022526-j9kg00qf 2689 4 , , , cord-022526-j9kg00qf 2689 5 pyloric pyloric JJ cord-022526-j9kg00qf 2689 6 , , , cord-022526-j9kg00qf 2689 7 or or CC cord-022526-j9kg00qf 2689 8 stricture stricture NN cord-022526-j9kg00qf 2689 9 formation formation NN cord-022526-j9kg00qf 2689 10 is be VBZ cord-022526-j9kg00qf 2689 11 high high JJ cord-022526-j9kg00qf 2689 12 if if IN cord-022526-j9kg00qf 2689 13 severe severe JJ cord-022526-j9kg00qf 2689 14 circumferential circumferential NN cord-022526-j9kg00qf 2689 15 or or CC cord-022526-j9kg00qf 2689 16 coalescing coalescing JJ cord-022526-j9kg00qf 2689 17 ulcerations ulceration NNS cord-022526-j9kg00qf 2689 18 are be VBP cord-022526-j9kg00qf 2689 19 present present JJ cord-022526-j9kg00qf 2689 20 . . . cord-022526-j9kg00qf 2690 1 Esophagitis Esophagitis NNP cord-022526-j9kg00qf 2690 2 from from IN cord-022526-j9kg00qf 2690 3 severe severe JJ cord-022526-j9kg00qf 2690 4 trauma trauma NN cord-022526-j9kg00qf 2690 5 or or CC cord-022526-j9kg00qf 2690 6 infection infection NN cord-022526-j9kg00qf 2690 7 may may MD cord-022526-j9kg00qf 2690 8 be be VB cord-022526-j9kg00qf 2690 9 prone prone JJ cord-022526-j9kg00qf 2690 10 to to IN cord-022526-j9kg00qf 2690 11 stricture stricture NN cord-022526-j9kg00qf 2690 12 formation formation NN cord-022526-j9kg00qf 2690 13 . . . cord-022526-j9kg00qf 2691 1 Motility motility NN cord-022526-j9kg00qf 2691 2 dysfunction dysfunction NN cord-022526-j9kg00qf 2691 3 of of IN cord-022526-j9kg00qf 2691 4 the the DT cord-022526-j9kg00qf 2691 5 equine equine JJ cord-022526-j9kg00qf 2691 6 esophagus esophagus NN cord-022526-j9kg00qf 2691 7 is be VBZ cord-022526-j9kg00qf 2691 8 caused cause VBN cord-022526-j9kg00qf 2691 9 most most RBS cord-022526-j9kg00qf 2691 10 commonly commonly RB cord-022526-j9kg00qf 2691 11 by by IN cord-022526-j9kg00qf 2691 12 hypomotility hypomotility NN cord-022526-j9kg00qf 2691 13 resulting result VBG cord-022526-j9kg00qf 2691 14 in in IN cord-022526-j9kg00qf 2691 15 esophageal esophageal JJ cord-022526-j9kg00qf 2691 16 dilation dilation NN cord-022526-j9kg00qf 2691 17 ( ( -LRB- cord-022526-j9kg00qf 2691 18 ectasia ectasia NNP cord-022526-j9kg00qf 2691 19 ) ) -RRB- cord-022526-j9kg00qf 2691 20 or or CC cord-022526-j9kg00qf 2691 21 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2691 22 . . . cord-022526-j9kg00qf 2692 1 Although although IN cord-022526-j9kg00qf 2692 2 megaesophagus megaesophagu VBN cord-022526-j9kg00qf 2692 3 in in IN cord-022526-j9kg00qf 2692 4 horses horse NNS cord-022526-j9kg00qf 2692 5 most most RBS cord-022526-j9kg00qf 2692 6 commonly commonly RB cord-022526-j9kg00qf 2692 7 is be VBZ cord-022526-j9kg00qf 2692 8 acquired acquire VBN cord-022526-j9kg00qf 2692 9 , , , cord-022526-j9kg00qf 2692 10 reports report NNS cord-022526-j9kg00qf 2692 11 indicate indicate VBP cord-022526-j9kg00qf 2692 12 idiopathic idiopathic JJ cord-022526-j9kg00qf 2692 13 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2692 14 in in IN cord-022526-j9kg00qf 2692 15 young young JJ cord-022526-j9kg00qf 2692 16 horses horse NNS cord-022526-j9kg00qf 2692 17 may may MD cord-022526-j9kg00qf 2692 18 be be VB cord-022526-j9kg00qf 2692 19 congenital congenital JJ cord-022526-j9kg00qf 2692 20 . . . cord-022526-j9kg00qf 2693 1 [ [ -LRB- cord-022526-j9kg00qf 2693 2 28 28 CD cord-022526-j9kg00qf 2693 3 ] ] -RRB- cord-022526-j9kg00qf 2693 4 [ [ -LRB- cord-022526-j9kg00qf 2693 5 29 29 CD cord-022526-j9kg00qf 2693 6 ] ] -RRB- cord-022526-j9kg00qf 2694 1 [ [ -LRB- cord-022526-j9kg00qf 2694 2 30 30 CD cord-022526-j9kg00qf 2694 3 ] ] -RRB- cord-022526-j9kg00qf 2694 4 [ [ -LRB- cord-022526-j9kg00qf 2694 5 31 31 CD cord-022526-j9kg00qf 2694 6 ] ] -RRB- cord-022526-j9kg00qf 2694 7 Acquired acquire VBN cord-022526-j9kg00qf 2695 1 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2695 2 in in IN cord-022526-j9kg00qf 2695 3 horses horse NNS cord-022526-j9kg00qf 2695 4 may may MD cord-022526-j9kg00qf 2695 5 be be VB cord-022526-j9kg00qf 2695 6 a a DT cord-022526-j9kg00qf 2695 7 consequence consequence NN cord-022526-j9kg00qf 2695 8 of of IN cord-022526-j9kg00qf 2695 9 chronic chronic JJ cord-022526-j9kg00qf 2695 10 or or CC cord-022526-j9kg00qf 2695 11 recurrent recurrent JJ cord-022526-j9kg00qf 2695 12 esophageal esophageal JJ cord-022526-j9kg00qf 2695 13 obstruction obstruction NN cord-022526-j9kg00qf 2695 14 . . . cord-022526-j9kg00qf 2696 1 3 3 CD cord-022526-j9kg00qf 2696 2 , , , cord-022526-j9kg00qf 2696 3 7 7 CD cord-022526-j9kg00qf 2696 4 Esophageal esophageal JJ cord-022526-j9kg00qf 2696 5 impactions impaction NNS cord-022526-j9kg00qf 2696 6 of of IN cord-022526-j9kg00qf 2696 7 a a DT cord-022526-j9kg00qf 2696 8 short short JJ cord-022526-j9kg00qf 2696 9 duration duration NN cord-022526-j9kg00qf 2696 10 cause cause VB cord-022526-j9kg00qf 2696 11 a a DT cord-022526-j9kg00qf 2696 12 proximal proximal JJ cord-022526-j9kg00qf 2696 13 dilation dilation NN cord-022526-j9kg00qf 2696 14 of of IN cord-022526-j9kg00qf 2696 15 the the DT cord-022526-j9kg00qf 2696 16 esophagus esophagus NN cord-022526-j9kg00qf 2696 17 that that WDT cord-022526-j9kg00qf 2696 18 is be VBZ cord-022526-j9kg00qf 2696 19 generally generally RB cord-022526-j9kg00qf 2696 20 reversible reversible JJ cord-022526-j9kg00qf 2696 21 . . . cord-022526-j9kg00qf 2697 1 14 14 CD cord-022526-j9kg00qf 2698 1 However however RB cord-022526-j9kg00qf 2698 2 , , , cord-022526-j9kg00qf 2698 3 if if IN cord-022526-j9kg00qf 2698 4 the the DT cord-022526-j9kg00qf 2698 5 duration duration NN cord-022526-j9kg00qf 2698 6 of of IN cord-022526-j9kg00qf 2698 7 the the DT cord-022526-j9kg00qf 2698 8 obstruction obstruction NN cord-022526-j9kg00qf 2698 9 is be VBZ cord-022526-j9kg00qf 2698 10 long long RB cord-022526-j9kg00qf 2698 11 enough enough RB cord-022526-j9kg00qf 2698 12 , , , cord-022526-j9kg00qf 2698 13 the the DT cord-022526-j9kg00qf 2698 14 motility motility NN cord-022526-j9kg00qf 2698 15 of of IN cord-022526-j9kg00qf 2698 16 the the DT cord-022526-j9kg00qf 2698 17 esophagus esophagus NN cord-022526-j9kg00qf 2698 18 proximal proximal JJ cord-022526-j9kg00qf 2698 19 to to IN cord-022526-j9kg00qf 2698 20 the the DT cord-022526-j9kg00qf 2698 21 site site NN cord-022526-j9kg00qf 2698 22 of of IN cord-022526-j9kg00qf 2698 23 obstruction obstruction NN cord-022526-j9kg00qf 2698 24 may may MD cord-022526-j9kg00qf 2698 25 be be VB cord-022526-j9kg00qf 2698 26 impaired impair VBN cord-022526-j9kg00qf 2698 27 permanently permanently RB cord-022526-j9kg00qf 2698 28 . . . cord-022526-j9kg00qf 2699 1 Other other JJ cord-022526-j9kg00qf 2699 2 causes cause NNS cord-022526-j9kg00qf 2699 3 of of IN cord-022526-j9kg00qf 2699 4 acquired acquire VBN cord-022526-j9kg00qf 2699 5 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2699 6 include include VBP cord-022526-j9kg00qf 2699 7 extraesophageal extraesophageal NN cord-022526-j9kg00qf 2699 8 obstruction obstruction NN cord-022526-j9kg00qf 2699 9 by by IN cord-022526-j9kg00qf 2699 10 tumors tumor NNS cord-022526-j9kg00qf 2699 11 or or CC cord-022526-j9kg00qf 2699 12 abscesses abscess NNS cord-022526-j9kg00qf 2699 13 , , , cord-022526-j9kg00qf 2699 14 pleuropneumonia pleuropneumonia NNP cord-022526-j9kg00qf 2699 15 , , , cord-022526-j9kg00qf 2699 16 and and CC cord-022526-j9kg00qf 2699 17 vascular vascular JJ cord-022526-j9kg00qf 2699 18 ring ring NN cord-022526-j9kg00qf 2699 19 anomalies anomaly NNS cord-022526-j9kg00qf 2699 20 . . . cord-022526-j9kg00qf 2700 1 3 3 CD cord-022526-j9kg00qf 2700 2 , , , cord-022526-j9kg00qf 2700 3 8 8 CD cord-022526-j9kg00qf 2700 4 Acquired acquire VBN cord-022526-j9kg00qf 2700 5 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2700 6 also also RB cord-022526-j9kg00qf 2700 7 may may MD cord-022526-j9kg00qf 2700 8 result result VB cord-022526-j9kg00qf 2700 9 from from IN cord-022526-j9kg00qf 2700 10 neurologic neurologic JJ cord-022526-j9kg00qf 2700 11 , , , cord-022526-j9kg00qf 2700 12 neuromuscular neuromuscular NN cord-022526-j9kg00qf 2700 13 , , , cord-022526-j9kg00qf 2700 14 and and CC cord-022526-j9kg00qf 2700 15 muscular muscular JJ cord-022526-j9kg00qf 2700 16 disorders disorder NNS cord-022526-j9kg00qf 2700 17 . . . cord-022526-j9kg00qf 2701 1 Neurologic neurologic JJ cord-022526-j9kg00qf 2701 2 diseases disease NNS cord-022526-j9kg00qf 2701 3 that that WDT cord-022526-j9kg00qf 2701 4 cause cause VBP cord-022526-j9kg00qf 2701 5 vagal vagal JJ cord-022526-j9kg00qf 2701 6 neuropathy neuropathy NN cord-022526-j9kg00qf 2701 7 - - , cord-022526-j9kg00qf 2701 8 such such JJ cord-022526-j9kg00qf 2701 9 as as IN cord-022526-j9kg00qf 2701 10 equine equine JJ cord-022526-j9kg00qf 2701 11 protozoal protozoal NN cord-022526-j9kg00qf 2701 12 myeloencephalitis myeloencephalitis NN cord-022526-j9kg00qf 2701 13 , , , cord-022526-j9kg00qf 2701 14 equine equine JJ cord-022526-j9kg00qf 2701 15 herpesvirus herpesvirus NN cord-022526-j9kg00qf 2701 16 myeloencephalitis myeloencephalitis NN cord-022526-j9kg00qf 2701 17 , , , cord-022526-j9kg00qf 2701 18 and and CC cord-022526-j9kg00qf 2701 19 idiopathic idiopathic JJ cord-022526-j9kg00qf 2701 20 vagal vagal JJ cord-022526-j9kg00qf 2701 21 neuropathy neuropathy NN cord-022526-j9kg00qf 2701 22 - - , cord-022526-j9kg00qf 2701 23 have have VBP cord-022526-j9kg00qf 2701 24 been be VBN cord-022526-j9kg00qf 2701 25 associated associate VBN cord-022526-j9kg00qf 2701 26 with with IN cord-022526-j9kg00qf 2701 27 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2701 28 in in IN cord-022526-j9kg00qf 2701 29 horses horse NNS cord-022526-j9kg00qf 2701 30 . . . cord-022526-j9kg00qf 2702 1 Pleuropneumonia Pleuropneumonia NNP cord-022526-j9kg00qf 2702 2 may may MD cord-022526-j9kg00qf 2702 3 be be VB cord-022526-j9kg00qf 2702 4 associated associate VBN cord-022526-j9kg00qf 2702 5 with with IN cord-022526-j9kg00qf 2702 6 a a DT cord-022526-j9kg00qf 2702 7 vagal vagal JJ cord-022526-j9kg00qf 2702 8 neuropathy neuropathy NN cord-022526-j9kg00qf 2702 9 resulting result VBG cord-022526-j9kg00qf 2702 10 in in IN cord-022526-j9kg00qf 2702 11 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2702 12 . . . cord-022526-j9kg00qf 2703 1 Megaesophagus Megaesophagus NNP cord-022526-j9kg00qf 2703 2 is be VBZ cord-022526-j9kg00qf 2703 3 an an DT cord-022526-j9kg00qf 2703 4 early early JJ cord-022526-j9kg00qf 2703 5 sign sign NN cord-022526-j9kg00qf 2703 6 of of IN cord-022526-j9kg00qf 2703 7 equine equine JJ cord-022526-j9kg00qf 2703 8 dysautonomia dysautonomia NN cord-022526-j9kg00qf 2703 9 32 32 CD cord-022526-j9kg00qf 2703 10 and and CC cord-022526-j9kg00qf 2703 11 may may MD cord-022526-j9kg00qf 2703 12 be be VB cord-022526-j9kg00qf 2703 13 observable observable JJ cord-022526-j9kg00qf 2703 14 in in IN cord-022526-j9kg00qf 2703 15 patients patient NNS cord-022526-j9kg00qf 2703 16 with with IN cord-022526-j9kg00qf 2703 17 botulism botulism NN cord-022526-j9kg00qf 2703 18 . . . cord-022526-j9kg00qf 2704 1 Myasthenia myasthenia NN cord-022526-j9kg00qf 2704 2 gravis gravis NN cord-022526-j9kg00qf 2704 3 is be VBZ cord-022526-j9kg00qf 2704 4 a a DT cord-022526-j9kg00qf 2704 5 well well RB cord-022526-j9kg00qf 2704 6 - - HYPH cord-022526-j9kg00qf 2704 7 known know VBN cord-022526-j9kg00qf 2704 8 cause cause NN cord-022526-j9kg00qf 2704 9 of of IN cord-022526-j9kg00qf 2704 10 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2704 11 in in IN cord-022526-j9kg00qf 2704 12 nonequine nonequine NNP cord-022526-j9kg00qf 2704 13 species species NNP cord-022526-j9kg00qf 2704 14 but but CC cord-022526-j9kg00qf 2704 15 has have VBZ cord-022526-j9kg00qf 2704 16 not not RB cord-022526-j9kg00qf 2704 17 been be VBN cord-022526-j9kg00qf 2704 18 reported report VBN cord-022526-j9kg00qf 2704 19 in in IN cord-022526-j9kg00qf 2704 20 horses horse NNS cord-022526-j9kg00qf 2704 21 . . . cord-022526-j9kg00qf 2705 1 Also also RB cord-022526-j9kg00qf 2705 2 in in IN cord-022526-j9kg00qf 2705 3 other other JJ cord-022526-j9kg00qf 2705 4 species specie NNS cord-022526-j9kg00qf 2705 5 , , , cord-022526-j9kg00qf 2705 6 electrolyte electrolyte JJ cord-022526-j9kg00qf 2705 7 disorders disorder NNS cord-022526-j9kg00qf 2705 8 , , , cord-022526-j9kg00qf 2705 9 cachexia cachexia NN cord-022526-j9kg00qf 2705 10 , , , cord-022526-j9kg00qf 2705 11 primary primary JJ cord-022526-j9kg00qf 2705 12 myopathies myopathy NNS cord-022526-j9kg00qf 2705 13 , , , cord-022526-j9kg00qf 2705 14 myositis myositis NN cord-022526-j9kg00qf 2705 15 , , , cord-022526-j9kg00qf 2705 16 and and CC cord-022526-j9kg00qf 2705 17 Addison Addison NNP cord-022526-j9kg00qf 2705 18 's 's POS cord-022526-j9kg00qf 2705 19 disease disease NN cord-022526-j9kg00qf 2705 20 may may MD cord-022526-j9kg00qf 2705 21 affect affect VB cord-022526-j9kg00qf 2705 22 esophageal esophageal JJ cord-022526-j9kg00qf 2705 23 motility motility NN cord-022526-j9kg00qf 2705 24 but but CC cord-022526-j9kg00qf 2705 25 have have VBP cord-022526-j9kg00qf 2705 26 not not RB cord-022526-j9kg00qf 2705 27 been be VBN cord-022526-j9kg00qf 2705 28 associated associate VBN cord-022526-j9kg00qf 2705 29 with with IN cord-022526-j9kg00qf 2705 30 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2705 31 in in IN cord-022526-j9kg00qf 2705 32 horses horse NNS cord-022526-j9kg00qf 2705 33 . . . cord-022526-j9kg00qf 2706 1 One one PRP cord-022526-j9kg00qf 2706 2 can can MD cord-022526-j9kg00qf 2706 3 induce induce VB cord-022526-j9kg00qf 2706 4 iatrogenic iatrogenic JJ cord-022526-j9kg00qf 2706 5 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2706 6 by by IN cord-022526-j9kg00qf 2706 7 the the DT cord-022526-j9kg00qf 2706 8 α α NN cord-022526-j9kg00qf 2706 9 2adrenergic 2adrenergic CD cord-022526-j9kg00qf 2706 10 agonist agonist NN cord-022526-j9kg00qf 2706 11 detomidine detomidine NN cord-022526-j9kg00qf 2706 12 , , , cord-022526-j9kg00qf 2706 13 but but CC cord-022526-j9kg00qf 2706 14 this this DT cord-022526-j9kg00qf 2706 15 is be VBZ cord-022526-j9kg00qf 2706 16 transient transient JJ cord-022526-j9kg00qf 2706 17 and and CC cord-022526-j9kg00qf 2706 18 reversible reversible JJ cord-022526-j9kg00qf 2706 19 . . . cord-022526-j9kg00qf 2707 1 17 17 CD cord-022526-j9kg00qf 2707 2 , , , cord-022526-j9kg00qf 2707 3 33 33 CD cord-022526-j9kg00qf 2707 4 Nonetheless nonetheless RB cord-022526-j9kg00qf 2707 5 , , , cord-022526-j9kg00qf 2707 6 the the DT cord-022526-j9kg00qf 2707 7 use use NN cord-022526-j9kg00qf 2707 8 of of IN cord-022526-j9kg00qf 2707 9 this this DT cord-022526-j9kg00qf 2707 10 drug drug NN cord-022526-j9kg00qf 2707 11 may may MD cord-022526-j9kg00qf 2707 12 complicate complicate VB cord-022526-j9kg00qf 2707 13 clinical clinical JJ cord-022526-j9kg00qf 2707 14 evaluation evaluation NN cord-022526-j9kg00qf 2707 15 of of IN cord-022526-j9kg00qf 2707 16 esophageal esophageal JJ cord-022526-j9kg00qf 2707 17 motility motility NN cord-022526-j9kg00qf 2707 18 . . . cord-022526-j9kg00qf 2708 1 Esophageal esophageal JJ cord-022526-j9kg00qf 2708 2 inflammation inflammation NN cord-022526-j9kg00qf 2708 3 , , , cord-022526-j9kg00qf 2708 4 particularly particularly RB cord-022526-j9kg00qf 2708 5 reflux reflux NN cord-022526-j9kg00qf 2708 6 esophagitis esophagitis NN cord-022526-j9kg00qf 2708 7 , , , cord-022526-j9kg00qf 2708 8 may may MD cord-022526-j9kg00qf 2708 9 affect affect VB cord-022526-j9kg00qf 2708 10 motility motility NN cord-022526-j9kg00qf 2708 11 and and CC cord-022526-j9kg00qf 2708 12 cause cause VB cord-022526-j9kg00qf 2708 13 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2708 14 . . . cord-022526-j9kg00qf 2709 1 However however RB cord-022526-j9kg00qf 2709 2 , , , cord-022526-j9kg00qf 2709 3 because because IN cord-022526-j9kg00qf 2709 4 esophageal esophageal JJ cord-022526-j9kg00qf 2709 5 hypomotility hypomotility NN cord-022526-j9kg00qf 2709 6 affects affect VBZ cord-022526-j9kg00qf 2709 7 the the DT cord-022526-j9kg00qf 2709 8 tone tone NN cord-022526-j9kg00qf 2709 9 and and CC cord-022526-j9kg00qf 2709 10 function function NN cord-022526-j9kg00qf 2709 11 of of IN cord-022526-j9kg00qf 2709 12 the the DT cord-022526-j9kg00qf 2709 13 lower low JJR cord-022526-j9kg00qf 2709 14 esophageal esophageal JJ cord-022526-j9kg00qf 2709 15 sphincter sphincter NN cord-022526-j9kg00qf 2709 16 , , , cord-022526-j9kg00qf 2709 17 reflux reflux NN cord-022526-j9kg00qf 2709 18 esophagitis esophagitis NN cord-022526-j9kg00qf 2709 19 also also RB cord-022526-j9kg00qf 2709 20 may may MD cord-022526-j9kg00qf 2709 21 be be VB cord-022526-j9kg00qf 2709 22 a a DT cord-022526-j9kg00qf 2709 23 complication complication NN cord-022526-j9kg00qf 2709 24 of of IN cord-022526-j9kg00qf 2709 25 a a DT cord-022526-j9kg00qf 2709 26 primary primary JJ cord-022526-j9kg00qf 2709 27 functional functional JJ cord-022526-j9kg00qf 2709 28 disorder disorder NN cord-022526-j9kg00qf 2709 29 . . . cord-022526-j9kg00qf 2710 1 Thus thus RB cord-022526-j9kg00qf 2710 2 assessing assess VBG cord-022526-j9kg00qf 2710 3 esophageal esophageal JJ cord-022526-j9kg00qf 2710 4 motility motility NN cord-022526-j9kg00qf 2710 5 in in IN cord-022526-j9kg00qf 2710 6 horses horse NNS cord-022526-j9kg00qf 2710 7 with with IN cord-022526-j9kg00qf 2710 8 esophagitis esophagitis NN cord-022526-j9kg00qf 2710 9 that that WDT cord-022526-j9kg00qf 2710 10 is be VBZ cord-022526-j9kg00qf 2710 11 not not RB cord-022526-j9kg00qf 2710 12 responding respond VBG cord-022526-j9kg00qf 2710 13 appropriately appropriately RB cord-022526-j9kg00qf 2710 14 to to IN cord-022526-j9kg00qf 2710 15 treatment treatment NN cord-022526-j9kg00qf 2710 16 is be VBZ cord-022526-j9kg00qf 2710 17 important important JJ cord-022526-j9kg00qf 2710 18 . . . cord-022526-j9kg00qf 2711 1 Along along IN cord-022526-j9kg00qf 2711 2 with with IN cord-022526-j9kg00qf 2711 3 a a DT cord-022526-j9kg00qf 2711 4 complete complete JJ cord-022526-j9kg00qf 2711 5 physical physical JJ cord-022526-j9kg00qf 2711 6 examination examination NN cord-022526-j9kg00qf 2711 7 one one PRP cord-022526-j9kg00qf 2711 8 should should MD cord-022526-j9kg00qf 2711 9 include include VB cord-022526-j9kg00qf 2711 10 a a DT cord-022526-j9kg00qf 2711 11 careful careful JJ cord-022526-j9kg00qf 2711 12 neurologic neurologic JJ cord-022526-j9kg00qf 2711 13 examination examination NN cord-022526-j9kg00qf 2711 14 to to TO cord-022526-j9kg00qf 2711 15 help help VB cord-022526-j9kg00qf 2711 16 rule rule VB cord-022526-j9kg00qf 2711 17 out out RP cord-022526-j9kg00qf 2711 18 primary primary JJ cord-022526-j9kg00qf 2711 19 neurologic neurologic JJ cord-022526-j9kg00qf 2711 20 causes cause NNS cord-022526-j9kg00qf 2711 21 of of IN cord-022526-j9kg00qf 2711 22 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2711 23 . . . cord-022526-j9kg00qf 2712 1 Because because IN cord-022526-j9kg00qf 2712 2 esophageal esophageal JJ cord-022526-j9kg00qf 2712 3 hypomotility hypomotility NN cord-022526-j9kg00qf 2712 4 is be VBZ cord-022526-j9kg00qf 2712 5 a a DT cord-022526-j9kg00qf 2712 6 functional functional JJ cord-022526-j9kg00qf 2712 7 obstruction obstruction NN cord-022526-j9kg00qf 2712 8 , , , cord-022526-j9kg00qf 2712 9 the the DT cord-022526-j9kg00qf 2712 10 clinical clinical JJ cord-022526-j9kg00qf 2712 11 signs sign NNS cord-022526-j9kg00qf 2712 12 of of IN cord-022526-j9kg00qf 2712 13 esophageal esophageal JJ cord-022526-j9kg00qf 2712 14 hypomotility hypomotility NN cord-022526-j9kg00qf 2712 15 or or CC cord-022526-j9kg00qf 2712 16 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2712 17 are be VBP cord-022526-j9kg00qf 2712 18 similar similar JJ cord-022526-j9kg00qf 2712 19 to to IN cord-022526-j9kg00qf 2712 20 esophageal esophageal JJ cord-022526-j9kg00qf 2712 21 obstruction obstruction NN cord-022526-j9kg00qf 2712 22 . . . cord-022526-j9kg00qf 2713 1 Unlike unlike IN cord-022526-j9kg00qf 2713 2 mechanical mechanical JJ cord-022526-j9kg00qf 2713 3 obstruction obstruction NN cord-022526-j9kg00qf 2713 4 the the DT cord-022526-j9kg00qf 2713 5 onset onset NN cord-022526-j9kg00qf 2713 6 of of IN cord-022526-j9kg00qf 2713 7 clinical clinical JJ cord-022526-j9kg00qf 2713 8 signs sign NNS cord-022526-j9kg00qf 2713 9 is be VBZ cord-022526-j9kg00qf 2713 10 insidious insidious JJ cord-022526-j9kg00qf 2713 11 rather rather RB cord-022526-j9kg00qf 2713 12 than than IN cord-022526-j9kg00qf 2713 13 acute acute JJ cord-022526-j9kg00qf 2713 14 . . . cord-022526-j9kg00qf 2714 1 The the DT cord-022526-j9kg00qf 2714 2 clinical clinical JJ cord-022526-j9kg00qf 2714 3 signs sign NNS cord-022526-j9kg00qf 2714 4 include include VBP cord-022526-j9kg00qf 2714 5 those those DT cord-022526-j9kg00qf 2714 6 associated associate VBN cord-022526-j9kg00qf 2714 7 with with IN cord-022526-j9kg00qf 2714 8 esophageal esophageal JJ cord-022526-j9kg00qf 2714 9 dysphagia dysphagia NN cord-022526-j9kg00qf 2714 10 . . . cord-022526-j9kg00qf 2715 1 7 7 CD cord-022526-j9kg00qf 2715 2 , , , cord-022526-j9kg00qf 2715 3 8 8 CD cord-022526-j9kg00qf 2715 4 , , , cord-022526-j9kg00qf 2715 5 [ [ -LRB- cord-022526-j9kg00qf 2715 6 28 28 CD cord-022526-j9kg00qf 2715 7 ] ] -RRB- cord-022526-j9kg00qf 2715 8 [ [ -LRB- cord-022526-j9kg00qf 2715 9 29 29 CD cord-022526-j9kg00qf 2715 10 ] ] -RRB- cord-022526-j9kg00qf 2716 1 [ [ -LRB- cord-022526-j9kg00qf 2716 2 30 30 CD cord-022526-j9kg00qf 2716 3 ] ] -RRB- cord-022526-j9kg00qf 2716 4 [ [ -LRB- cord-022526-j9kg00qf 2716 5 31 31 CD cord-022526-j9kg00qf 2716 6 ] ] -RRB- cord-022526-j9kg00qf 2717 1 The the DT cord-022526-j9kg00qf 2717 2 cervical cervical JJ cord-022526-j9kg00qf 2717 3 esophagus esophagus NN cord-022526-j9kg00qf 2717 4 may may MD cord-022526-j9kg00qf 2717 5 be be VB cord-022526-j9kg00qf 2717 6 dilated dilate VBN cord-022526-j9kg00qf 2717 7 enough enough RB cord-022526-j9kg00qf 2717 8 to to TO cord-022526-j9kg00qf 2717 9 be be VB cord-022526-j9kg00qf 2717 10 evident evident JJ cord-022526-j9kg00qf 2717 11 externally externally RB cord-022526-j9kg00qf 2717 12 . . . cord-022526-j9kg00qf 2718 1 Weight weight NN cord-022526-j9kg00qf 2718 2 loss loss NN cord-022526-j9kg00qf 2718 3 is be VBZ cord-022526-j9kg00qf 2718 4 a a DT cord-022526-j9kg00qf 2718 5 common common JJ cord-022526-j9kg00qf 2718 6 sign sign NN cord-022526-j9kg00qf 2718 7 . . . cord-022526-j9kg00qf 2719 1 Signs sign NNS cord-022526-j9kg00qf 2719 2 attributable attributable JJ cord-022526-j9kg00qf 2719 3 to to IN cord-022526-j9kg00qf 2719 4 an an DT cord-022526-j9kg00qf 2719 5 underlying underlie VBG cord-022526-j9kg00qf 2719 6 disease disease NN cord-022526-j9kg00qf 2719 7 may may MD cord-022526-j9kg00qf 2719 8 be be VB cord-022526-j9kg00qf 2719 9 evident evident JJ cord-022526-j9kg00qf 2719 10 . . . cord-022526-j9kg00qf 2720 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 2720 2 of of IN cord-022526-j9kg00qf 2720 3 esophageal esophageal JJ cord-022526-j9kg00qf 2720 4 hypomotility hypomotility NN cord-022526-j9kg00qf 2720 5 requires require VBZ cord-022526-j9kg00qf 2720 6 transit transit NN cord-022526-j9kg00qf 2720 7 studies study NNS cord-022526-j9kg00qf 2720 8 . . . cord-022526-j9kg00qf 2721 1 One one PRP cord-022526-j9kg00qf 2721 2 can can MD cord-022526-j9kg00qf 2721 3 measure measure VB cord-022526-j9kg00qf 2721 4 the the DT cord-022526-j9kg00qf 2721 5 transit transit NN cord-022526-j9kg00qf 2721 6 time time NN cord-022526-j9kg00qf 2721 7 of of IN cord-022526-j9kg00qf 2721 8 a a DT cord-022526-j9kg00qf 2721 9 bolus bolus NN cord-022526-j9kg00qf 2721 10 from from IN cord-022526-j9kg00qf 2721 11 the the DT cord-022526-j9kg00qf 2721 12 cervical cervical JJ cord-022526-j9kg00qf 2721 13 esophagus esophagus NN cord-022526-j9kg00qf 2721 14 to to IN cord-022526-j9kg00qf 2721 15 the the DT cord-022526-j9kg00qf 2721 16 stomach stomach NN cord-022526-j9kg00qf 2721 17 by by IN cord-022526-j9kg00qf 2721 18 fluoroscopy fluoroscopy NN cord-022526-j9kg00qf 2721 19 or or CC cord-022526-j9kg00qf 2721 20 contrast contrast NN cord-022526-j9kg00qf 2721 21 radiography radiography NN cord-022526-j9kg00qf 2721 22 . . . cord-022526-j9kg00qf 2722 1 14,32 14,32 CD cord-022526-j9kg00qf 2722 2 Other other JJ cord-022526-j9kg00qf 2722 3 signs sign NNS cord-022526-j9kg00qf 2722 4 of of IN cord-022526-j9kg00qf 2722 5 esophageal esophageal JJ cord-022526-j9kg00qf 2722 6 hypomotility hypomotility NN cord-022526-j9kg00qf 2722 7 and and CC cord-022526-j9kg00qf 2722 8 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2722 9 include include VBP cord-022526-j9kg00qf 2722 10 pooling pool VBG cord-022526-j9kg00qf 2722 11 of of IN cord-022526-j9kg00qf 2722 12 contrast contrast NN cord-022526-j9kg00qf 2722 13 material material NN cord-022526-j9kg00qf 2722 14 and and CC cord-022526-j9kg00qf 2722 15 an an DT cord-022526-j9kg00qf 2722 16 absence absence NN cord-022526-j9kg00qf 2722 17 of of IN cord-022526-j9kg00qf 2722 18 peristaltic peristaltic JJ cord-022526-j9kg00qf 2722 19 constrictions constriction NNS cord-022526-j9kg00qf 2722 20 . . . cord-022526-j9kg00qf 2723 1 7,14,28,32 7,14,28,32 DT cord-022526-j9kg00qf 2723 2 Endoscopy Endoscopy NNP cord-022526-j9kg00qf 2723 3 may may MD cord-022526-j9kg00qf 2723 4 reveal reveal VB cord-022526-j9kg00qf 2723 5 a a DT cord-022526-j9kg00qf 2723 6 dilated dilated JJ cord-022526-j9kg00qf 2723 7 esophagus esophagus NN cord-022526-j9kg00qf 2723 8 and and CC cord-022526-j9kg00qf 2723 9 an an DT cord-022526-j9kg00qf 2723 10 absence absence NN cord-022526-j9kg00qf 2723 11 of of IN cord-022526-j9kg00qf 2723 12 peristaltic peristaltic JJ cord-022526-j9kg00qf 2723 13 waves wave NNS cord-022526-j9kg00qf 2723 14 . . . cord-022526-j9kg00qf 2724 1 7,28 7,28 CD cord-022526-j9kg00qf 2725 1 One one CD cord-022526-j9kg00qf 2725 2 may may MD cord-022526-j9kg00qf 2725 3 observe observe VB cord-022526-j9kg00qf 2725 4 evidence evidence NN cord-022526-j9kg00qf 2725 5 of of IN cord-022526-j9kg00qf 2725 6 underlying underlie VBG cord-022526-j9kg00qf 2725 7 disease disease NN cord-022526-j9kg00qf 2725 8 causing cause VBG cord-022526-j9kg00qf 2725 9 obstruction obstruction NN cord-022526-j9kg00qf 2725 10 or or CC cord-022526-j9kg00qf 2725 11 esophageal esophageal JJ cord-022526-j9kg00qf 2725 12 dilation dilation NN cord-022526-j9kg00qf 2725 13 . . . cord-022526-j9kg00qf 2726 1 3 3 LS cord-022526-j9kg00qf 2726 2 , , , cord-022526-j9kg00qf 2726 3 7 7 CD cord-022526-j9kg00qf 2726 4 One one PRP cord-022526-j9kg00qf 2726 5 should should MD cord-022526-j9kg00qf 2726 6 evaluate evaluate VB cord-022526-j9kg00qf 2726 7 the the DT cord-022526-j9kg00qf 2726 8 esophagus esophagus NN cord-022526-j9kg00qf 2726 9 for for IN cord-022526-j9kg00qf 2726 10 evidence evidence NN cord-022526-j9kg00qf 2726 11 of of IN cord-022526-j9kg00qf 2726 12 esophagitis esophagitis NN cord-022526-j9kg00qf 2726 13 that that WDT cord-022526-j9kg00qf 2726 14 is be VBZ cord-022526-j9kg00qf 2726 15 causing cause VBG cord-022526-j9kg00qf 2726 16 esophageal esophageal JJ cord-022526-j9kg00qf 2726 17 motility motility NN cord-022526-j9kg00qf 2726 18 dysfunction dysfunction NN cord-022526-j9kg00qf 2726 19 or or CC cord-022526-j9kg00qf 2726 20 is be VBZ cord-022526-j9kg00qf 2726 21 a a DT cord-022526-j9kg00qf 2726 22 result result NN cord-022526-j9kg00qf 2726 23 of of IN cord-022526-j9kg00qf 2726 24 impaired impaired JJ cord-022526-j9kg00qf 2726 25 esophageal esophageal JJ cord-022526-j9kg00qf 2726 26 clearance clearance NN cord-022526-j9kg00qf 2726 27 of of IN cord-022526-j9kg00qf 2726 28 gastric gastric JJ cord-022526-j9kg00qf 2726 29 fluid fluid NN cord-022526-j9kg00qf 2726 30 . . . cord-022526-j9kg00qf 2727 1 Esophageal esophageal JJ cord-022526-j9kg00qf 2727 2 manometry manometry NN cord-022526-j9kg00qf 2727 3 may may MD cord-022526-j9kg00qf 2727 4 be be VB cord-022526-j9kg00qf 2727 5 useful useful JJ cord-022526-j9kg00qf 2727 6 to to TO cord-022526-j9kg00qf 2727 7 document document VB cord-022526-j9kg00qf 2727 8 abnormal abnormal JJ cord-022526-j9kg00qf 2727 9 postdeglutition postdeglutition NN cord-022526-j9kg00qf 2727 10 contraction contraction NN cord-022526-j9kg00qf 2727 11 pressures pressure NNS cord-022526-j9kg00qf 2727 12 , , , cord-022526-j9kg00qf 2727 13 contraction contraction NN cord-022526-j9kg00qf 2727 14 time time NN cord-022526-j9kg00qf 2727 15 , , , cord-022526-j9kg00qf 2727 16 and and CC cord-022526-j9kg00qf 2727 17 propagation propagation NN cord-022526-j9kg00qf 2727 18 times time NNS cord-022526-j9kg00qf 2727 19 but but CC cord-022526-j9kg00qf 2727 20 is be VBZ cord-022526-j9kg00qf 2727 21 not not RB cord-022526-j9kg00qf 2727 22 often often RB cord-022526-j9kg00qf 2727 23 available available JJ cord-022526-j9kg00qf 2727 24 for for IN cord-022526-j9kg00qf 2727 25 routine routine JJ cord-022526-j9kg00qf 2727 26 clinical clinical JJ cord-022526-j9kg00qf 2727 27 application application NN cord-022526-j9kg00qf 2727 28 . . . cord-022526-j9kg00qf 2728 1 28 28 CD cord-022526-j9kg00qf 2728 2 , , , cord-022526-j9kg00qf 2728 3 34 34 CD cord-022526-j9kg00qf 2728 4 One one PRP cord-022526-j9kg00qf 2728 5 should should MD cord-022526-j9kg00qf 2728 6 perform perform VB cord-022526-j9kg00qf 2728 7 other other JJ cord-022526-j9kg00qf 2728 8 diagnostic diagnostic JJ cord-022526-j9kg00qf 2728 9 tests test NNS cord-022526-j9kg00qf 2728 10 such such JJ cord-022526-j9kg00qf 2728 11 as as IN cord-022526-j9kg00qf 2728 12 a a DT cord-022526-j9kg00qf 2728 13 complete complete JJ cord-022526-j9kg00qf 2728 14 blood blood NN cord-022526-j9kg00qf 2728 15 count count NN cord-022526-j9kg00qf 2728 16 and and CC cord-022526-j9kg00qf 2728 17 chemistry chemistry NN cord-022526-j9kg00qf 2728 18 to to TO cord-022526-j9kg00qf 2728 19 help help VB cord-022526-j9kg00qf 2728 20 determine determine VB cord-022526-j9kg00qf 2728 21 a a DT cord-022526-j9kg00qf 2728 22 possible possible JJ cord-022526-j9kg00qf 2728 23 underlying underlying JJ cord-022526-j9kg00qf 2728 24 cause cause NN cord-022526-j9kg00qf 2728 25 . . . cord-022526-j9kg00qf 2729 1 Cerebral cerebral JJ cord-022526-j9kg00qf 2729 2 spinal spinal JJ cord-022526-j9kg00qf 2729 3 fluid fluid JJ cord-022526-j9kg00qf 2729 4 analysis analysis NN cord-022526-j9kg00qf 2729 5 may may MD cord-022526-j9kg00qf 2729 6 be be VB cord-022526-j9kg00qf 2729 7 indicated indicate VBN cord-022526-j9kg00qf 2729 8 to to TO cord-022526-j9kg00qf 2729 9 rule rule VB cord-022526-j9kg00qf 2729 10 out out RP cord-022526-j9kg00qf 2729 11 neurologic neurologic JJ cord-022526-j9kg00qf 2729 12 disorders disorder NNS cord-022526-j9kg00qf 2729 13 . . . cord-022526-j9kg00qf 2730 1 Specialized specialized JJ cord-022526-j9kg00qf 2730 2 testing testing NN cord-022526-j9kg00qf 2730 3 such such JJ cord-022526-j9kg00qf 2730 4 as as IN cord-022526-j9kg00qf 2730 5 electromyography electromyography NN cord-022526-j9kg00qf 2730 6 to to TO cord-022526-j9kg00qf 2730 7 detect detect VB cord-022526-j9kg00qf 2730 8 neuromuscular neuromuscular JJ cord-022526-j9kg00qf 2730 9 disorders disorder NNS cord-022526-j9kg00qf 2730 10 may may MD cord-022526-j9kg00qf 2730 11 also also RB cord-022526-j9kg00qf 2730 12 be be VB cord-022526-j9kg00qf 2730 13 indicated indicate VBN cord-022526-j9kg00qf 2730 14 . . . cord-022526-j9kg00qf 2731 1 Treatment treatment NN cord-022526-j9kg00qf 2731 2 of of IN cord-022526-j9kg00qf 2731 3 esophageal esophageal JJ cord-022526-j9kg00qf 2731 4 hypomotility hypomotility NN cord-022526-j9kg00qf 2731 5 or or CC cord-022526-j9kg00qf 2731 6 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2731 7 should should MD cord-022526-j9kg00qf 2731 8 aim aim VB cord-022526-j9kg00qf 2731 9 at at IN cord-022526-j9kg00qf 2731 10 treating treat VBG cord-022526-j9kg00qf 2731 11 the the DT cord-022526-j9kg00qf 2731 12 underlying underlying JJ cord-022526-j9kg00qf 2731 13 cause cause NN cord-022526-j9kg00qf 2731 14 . . . cord-022526-j9kg00qf 2732 1 Dietary dietary JJ cord-022526-j9kg00qf 2732 2 modification modification NN cord-022526-j9kg00qf 2732 3 should should MD cord-022526-j9kg00qf 2732 4 aim aim VB cord-022526-j9kg00qf 2732 5 at at IN cord-022526-j9kg00qf 2732 6 improving improve VBG cord-022526-j9kg00qf 2732 7 esophageal esophageal JJ cord-022526-j9kg00qf 2732 8 transit transit NN cord-022526-j9kg00qf 2732 9 of of IN cord-022526-j9kg00qf 2732 10 food food NN cord-022526-j9kg00qf 2732 11 . . . cord-022526-j9kg00qf 2733 1 One one PRP cord-022526-j9kg00qf 2733 2 should should MD cord-022526-j9kg00qf 2733 3 feed feed VB cord-022526-j9kg00qf 2733 4 the the DT cord-022526-j9kg00qf 2733 5 horse horse NN cord-022526-j9kg00qf 2733 6 slurries slurry NNS cord-022526-j9kg00qf 2733 7 of of IN cord-022526-j9kg00qf 2733 8 pellets pellet NNS cord-022526-j9kg00qf 2733 9 , , , cord-022526-j9kg00qf 2733 10 and and CC cord-022526-j9kg00qf 2733 11 feeding feed VBG cord-022526-j9kg00qf 2733 12 from from IN cord-022526-j9kg00qf 2733 13 an an DT cord-022526-j9kg00qf 2733 14 elevated elevated JJ cord-022526-j9kg00qf 2733 15 position position NN cord-022526-j9kg00qf 2733 16 to to TO cord-022526-j9kg00qf 2733 17 promote promote VB cord-022526-j9kg00qf 2733 18 transit transit NN cord-022526-j9kg00qf 2733 19 may may MD cord-022526-j9kg00qf 2733 20 be be VB cord-022526-j9kg00qf 2733 21 beneficial beneficial JJ cord-022526-j9kg00qf 2733 22 . . . cord-022526-j9kg00qf 2734 1 Metoclopramide Metoclopramide NNP cord-022526-j9kg00qf 2734 2 or or CC cord-022526-j9kg00qf 2734 3 bethanechol bethanechol NNP cord-022526-j9kg00qf 2734 4 may may MD cord-022526-j9kg00qf 2734 5 benefit benefit VB cord-022526-j9kg00qf 2734 6 patients patient NNS cord-022526-j9kg00qf 2734 7 with with IN cord-022526-j9kg00qf 2734 8 reflux reflux NN cord-022526-j9kg00qf 2734 9 esophagitis esophagitis NN cord-022526-j9kg00qf 2734 10 associated associate VBN cord-022526-j9kg00qf 2734 11 with with IN cord-022526-j9kg00qf 2734 12 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2734 13 by by IN cord-022526-j9kg00qf 2734 14 increasing increase VBG cord-022526-j9kg00qf 2734 15 lower low JJR cord-022526-j9kg00qf 2734 16 esophageal esophageal JJ cord-022526-j9kg00qf 2734 17 tone tone NN cord-022526-j9kg00qf 2734 18 , , , cord-022526-j9kg00qf 2734 19 gastric gastric JJ cord-022526-j9kg00qf 2734 20 emptying emptying NN cord-022526-j9kg00qf 2734 21 , , , cord-022526-j9kg00qf 2734 22 and and CC cord-022526-j9kg00qf 2734 23 reducing reduce VBG cord-022526-j9kg00qf 2734 24 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2734 25 reflux reflux NN cord-022526-j9kg00qf 2734 26 . . . cord-022526-j9kg00qf 2735 1 The the DT cord-022526-j9kg00qf 2735 2 prognosis prognosis NN cord-022526-j9kg00qf 2735 3 depends depend VBZ cord-022526-j9kg00qf 2735 4 on on IN cord-022526-j9kg00qf 2735 5 the the DT cord-022526-j9kg00qf 2735 6 underlying underlying JJ cord-022526-j9kg00qf 2735 7 cause cause NN cord-022526-j9kg00qf 2735 8 and and CC cord-022526-j9kg00qf 2735 9 the the DT cord-022526-j9kg00qf 2735 10 degree degree NN cord-022526-j9kg00qf 2735 11 of of IN cord-022526-j9kg00qf 2735 12 dilation dilation NN cord-022526-j9kg00qf 2735 13 . . . cord-022526-j9kg00qf 2736 1 Although although IN cord-022526-j9kg00qf 2736 2 many many JJ cord-022526-j9kg00qf 2736 3 cases case NNS cord-022526-j9kg00qf 2736 4 of of IN cord-022526-j9kg00qf 2736 5 megaesophagus megaesophagus JJ cord-022526-j9kg00qf 2736 6 associated associate VBN cord-022526-j9kg00qf 2736 7 with with IN cord-022526-j9kg00qf 2736 8 reflux reflux NN cord-022526-j9kg00qf 2736 9 esophagitis esophagitis NN cord-022526-j9kg00qf 2736 10 respond respond VBP cord-022526-j9kg00qf 2736 11 well well RB cord-022526-j9kg00qf 2736 12 to to IN cord-022526-j9kg00qf 2736 13 treatment treatment NN cord-022526-j9kg00qf 2736 14 , , , cord-022526-j9kg00qf 2736 15 many many JJ cord-022526-j9kg00qf 2736 16 other other JJ cord-022526-j9kg00qf 2736 17 forms form NNS cord-022526-j9kg00qf 2736 18 of of IN cord-022526-j9kg00qf 2736 19 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2736 20 including include VBG cord-022526-j9kg00qf 2736 21 congenital congenital JJ cord-022526-j9kg00qf 2736 22 megaesophagus megaesophagu NNS cord-022526-j9kg00qf 2736 23 have have VBP cord-022526-j9kg00qf 2736 24 a a DT cord-022526-j9kg00qf 2736 25 poor poor JJ cord-022526-j9kg00qf 2736 26 prognosis prognosis NN cord-022526-j9kg00qf 2736 27 . . . cord-022526-j9kg00qf 2737 1 Strictures stricture NNS cord-022526-j9kg00qf 2737 2 most most RBS cord-022526-j9kg00qf 2737 3 commonly commonly RB cord-022526-j9kg00qf 2737 4 are be VBP cord-022526-j9kg00qf 2737 5 caused cause VBN cord-022526-j9kg00qf 2737 6 by by IN cord-022526-j9kg00qf 2737 7 pressure pressure NN cord-022526-j9kg00qf 2737 8 necrosis necrosis NN cord-022526-j9kg00qf 2737 9 from from IN cord-022526-j9kg00qf 2737 10 esophageal esophageal JJ cord-022526-j9kg00qf 2737 11 impactions impaction NNS cord-022526-j9kg00qf 2737 12 that that WDT cord-022526-j9kg00qf 2737 13 induce induce VBP cord-022526-j9kg00qf 2737 14 circumferential circumferential JJ cord-022526-j9kg00qf 2737 15 erosion erosion NN cord-022526-j9kg00qf 2737 16 or or CC cord-022526-j9kg00qf 2737 17 ulceration ulceration NN cord-022526-j9kg00qf 2737 18 of of IN cord-022526-j9kg00qf 2737 19 the the DT cord-022526-j9kg00qf 2737 20 esophageal esophageal JJ cord-022526-j9kg00qf 2737 21 mucosa mucosa NN cord-022526-j9kg00qf 2737 22 , , , cord-022526-j9kg00qf 2737 23 although although IN cord-022526-j9kg00qf 2737 24 esophageal esophageal JJ cord-022526-j9kg00qf 2737 25 injury injury NN cord-022526-j9kg00qf 2737 26 caused cause VBN cord-022526-j9kg00qf 2737 27 by by IN cord-022526-j9kg00qf 2737 28 oral oral JJ cord-022526-j9kg00qf 2737 29 administration administration NN cord-022526-j9kg00qf 2737 30 of of IN cord-022526-j9kg00qf 2737 31 corrosive corrosive JJ cord-022526-j9kg00qf 2737 32 medicinal medicinal JJ cord-022526-j9kg00qf 2737 33 agents agent NNS cord-022526-j9kg00qf 2737 34 and and CC cord-022526-j9kg00qf 2737 35 trauma trauma NN cord-022526-j9kg00qf 2737 36 to to IN cord-022526-j9kg00qf 2737 37 the the DT cord-022526-j9kg00qf 2737 38 neck neck NN cord-022526-j9kg00qf 2737 39 may may MD cord-022526-j9kg00qf 2737 40 also also RB cord-022526-j9kg00qf 2737 41 result result VB cord-022526-j9kg00qf 2737 42 in in IN cord-022526-j9kg00qf 2737 43 stricture stricture NN cord-022526-j9kg00qf 2737 44 formation formation NN cord-022526-j9kg00qf 2737 45 . . . cord-022526-j9kg00qf 2738 1 35 35 CD cord-022526-j9kg00qf 2738 2 Congenital congenital JJ cord-022526-j9kg00qf 2738 3 strictures stricture NNS cord-022526-j9kg00qf 2738 4 also also RB cord-022526-j9kg00qf 2738 5 have have VBP cord-022526-j9kg00qf 2738 6 been be VBN cord-022526-j9kg00qf 2738 7 reported report VBN cord-022526-j9kg00qf 2738 8 . . . cord-022526-j9kg00qf 2739 1 36 36 CD cord-022526-j9kg00qf 2739 2 Strictures stricture NNS cord-022526-j9kg00qf 2739 3 caused cause VBN cord-022526-j9kg00qf 2739 4 by by IN cord-022526-j9kg00qf 2739 5 mucosal mucosal NN cord-022526-j9kg00qf 2739 6 and and CC cord-022526-j9kg00qf 2739 7 submucosal submucosal NNP cord-022526-j9kg00qf 2739 8 trauma trauma NN cord-022526-j9kg00qf 2739 9 are be VBP cord-022526-j9kg00qf 2739 10 termed term VBN cord-022526-j9kg00qf 2739 11 esophageal esophageal JJ cord-022526-j9kg00qf 2739 12 webs web NNS cord-022526-j9kg00qf 2739 13 or or CC cord-022526-j9kg00qf 2739 14 rings ring NNS cord-022526-j9kg00qf 2739 15 . . . cord-022526-j9kg00qf 2740 1 Strictures stricture NNS cord-022526-j9kg00qf 2740 2 may may MD cord-022526-j9kg00qf 2740 3 also also RB cord-022526-j9kg00qf 2740 4 originate originate VB cord-022526-j9kg00qf 2740 5 in in IN cord-022526-j9kg00qf 2740 6 the the DT cord-022526-j9kg00qf 2740 7 muscular muscular JJ cord-022526-j9kg00qf 2740 8 layers layer NNS cord-022526-j9kg00qf 2740 9 and and CC cord-022526-j9kg00qf 2740 10 adventitia adventitia NN cord-022526-j9kg00qf 2740 11 of of IN cord-022526-j9kg00qf 2740 12 the the DT cord-022526-j9kg00qf 2740 13 esophagus esophagus NN cord-022526-j9kg00qf 2740 14 ( ( -LRB- cord-022526-j9kg00qf 2740 15 mural mural NN cord-022526-j9kg00qf 2740 16 strictures stricture NNS cord-022526-j9kg00qf 2740 17 ) ) -RRB- cord-022526-j9kg00qf 2740 18 or or CC cord-022526-j9kg00qf 2740 19 in in IN cord-022526-j9kg00qf 2740 20 all all DT cord-022526-j9kg00qf 2740 21 of of IN cord-022526-j9kg00qf 2740 22 the the DT cord-022526-j9kg00qf 2740 23 layers layer NNS cord-022526-j9kg00qf 2740 24 of of IN cord-022526-j9kg00qf 2740 25 the the DT cord-022526-j9kg00qf 2740 26 esophagus esophagus NN cord-022526-j9kg00qf 2740 27 ( ( -LRB- cord-022526-j9kg00qf 2740 28 annular annular JJ cord-022526-j9kg00qf 2740 29 stenosis stenosis NN cord-022526-j9kg00qf 2740 30 ) ) -RRB- cord-022526-j9kg00qf 2740 31 . . . cord-022526-j9kg00qf 2741 1 36 36 CD cord-022526-j9kg00qf 2741 2 , , , cord-022526-j9kg00qf 2741 3 37 37 CD cord-022526-j9kg00qf 2741 4 Horses horse NNS cord-022526-j9kg00qf 2741 5 with with IN cord-022526-j9kg00qf 2741 6 these these DT cord-022526-j9kg00qf 2741 7 lesions lesion NNS cord-022526-j9kg00qf 2741 8 have have VBP cord-022526-j9kg00qf 2741 9 a a DT cord-022526-j9kg00qf 2741 10 presentation presentation NN cord-022526-j9kg00qf 2741 11 similar similar JJ cord-022526-j9kg00qf 2741 12 to to IN cord-022526-j9kg00qf 2741 13 those those DT cord-022526-j9kg00qf 2741 14 with with IN cord-022526-j9kg00qf 2741 15 simple simple JJ cord-022526-j9kg00qf 2741 16 obstructions obstruction NNS cord-022526-j9kg00qf 2741 17 , , , cord-022526-j9kg00qf 2741 18 because because IN cord-022526-j9kg00qf 2741 19 strictures stricture NNS cord-022526-j9kg00qf 2741 20 result result VBP cord-022526-j9kg00qf 2741 21 in in IN cord-022526-j9kg00qf 2741 22 partial partial JJ cord-022526-j9kg00qf 2741 23 obstruction obstruction NN cord-022526-j9kg00qf 2741 24 and and CC cord-022526-j9kg00qf 2741 25 impaction impaction NN cord-022526-j9kg00qf 2741 26 of of IN cord-022526-j9kg00qf 2741 27 food food NN cord-022526-j9kg00qf 2741 28 material material NN cord-022526-j9kg00qf 2741 29 in in IN cord-022526-j9kg00qf 2741 30 the the DT cord-022526-j9kg00qf 2741 31 lumen lumen NN cord-022526-j9kg00qf 2741 32 . . . cord-022526-j9kg00qf 2742 1 One one PRP cord-022526-j9kg00qf 2742 2 can can MD cord-022526-j9kg00qf 2742 3 detect detect VB cord-022526-j9kg00qf 2742 4 esophageal esophageal JJ cord-022526-j9kg00qf 2742 5 webs web NNS cord-022526-j9kg00qf 2742 6 or or CC cord-022526-j9kg00qf 2742 7 rings ring NNS cord-022526-j9kg00qf 2742 8 with with IN cord-022526-j9kg00qf 2742 9 endoscopy endoscopy NN cord-022526-j9kg00qf 2742 10 ( ( -LRB- cord-022526-j9kg00qf 2742 11 see see VB cord-022526-j9kg00qf 2742 12 Figure figure NN cord-022526-j9kg00qf 2742 13 13 13 CD cord-022526-j9kg00qf 2742 14 .9 .9 CD cord-022526-j9kg00qf 2742 15 - - SYM cord-022526-j9kg00qf 2742 16 1 1 CD cord-022526-j9kg00qf 2742 17 ) ) -RRB- cord-022526-j9kg00qf 2742 18 , , , cord-022526-j9kg00qf 2742 19 whereas whereas IN cord-022526-j9kg00qf 2742 20 identification identification NN cord-022526-j9kg00qf 2742 21 of of IN cord-022526-j9kg00qf 2742 22 mural mural NN cord-022526-j9kg00qf 2742 23 strictures stricture NNS cord-022526-j9kg00qf 2742 24 or or CC cord-022526-j9kg00qf 2742 25 annular annular JJ cord-022526-j9kg00qf 2742 26 stenosis stenosis NN cord-022526-j9kg00qf 2742 27 may may MD cord-022526-j9kg00qf 2742 28 require require VB cord-022526-j9kg00qf 2742 29 a a DT cord-022526-j9kg00qf 2742 30 double double JJ cord-022526-j9kg00qf 2742 31 - - HYPH cord-022526-j9kg00qf 2742 32 contrast contrast NN cord-022526-j9kg00qf 2742 33 esophogram esophogram NNP cord-022526-j9kg00qf 2742 34 ( ( -LRB- cord-022526-j9kg00qf 2742 35 see see VB cord-022526-j9kg00qf 2742 36 Figure Figure NNP cord-022526-j9kg00qf 2742 37 13 13 CD cord-022526-j9kg00qf 2742 38 .9 .9 CD cord-022526-j9kg00qf 2742 39 - - SYM cord-022526-j9kg00qf 2742 40 2 2 CD cord-022526-j9kg00qf 2742 41 ) ) -RRB- cord-022526-j9kg00qf 2742 42 . . . cord-022526-j9kg00qf 2743 1 In in IN cord-022526-j9kg00qf 2743 2 a a DT cord-022526-j9kg00qf 2743 3 retrospective retrospective JJ cord-022526-j9kg00qf 2743 4 study study NN cord-022526-j9kg00qf 2743 5 of of IN cord-022526-j9kg00qf 2743 6 horses horse NNS cord-022526-j9kg00qf 2743 7 with with IN cord-022526-j9kg00qf 2743 8 esophageal esophageal JJ cord-022526-j9kg00qf 2743 9 stricture stricture NN cord-022526-j9kg00qf 2743 10 following follow VBG cord-022526-j9kg00qf 2743 11 simple simple JJ cord-022526-j9kg00qf 2743 12 obstruction obstruction NN cord-022526-j9kg00qf 2743 13 , , , cord-022526-j9kg00qf 2743 14 maximal maximal JJ cord-022526-j9kg00qf 2743 15 reduction reduction NN cord-022526-j9kg00qf 2743 16 in in IN cord-022526-j9kg00qf 2743 17 esophageal esophageal JJ cord-022526-j9kg00qf 2743 18 lumen lumen NN cord-022526-j9kg00qf 2743 19 diameter diameter NN cord-022526-j9kg00qf 2743 20 occurred occur VBD cord-022526-j9kg00qf 2743 21 within within IN cord-022526-j9kg00qf 2743 22 30 30 CD cord-022526-j9kg00qf 2743 23 days day NNS cord-022526-j9kg00qf 2743 24 of of IN cord-022526-j9kg00qf 2743 25 the the DT cord-022526-j9kg00qf 2743 26 esophageal esophageal JJ cord-022526-j9kg00qf 2743 27 obstruction obstruction NN cord-022526-j9kg00qf 2743 28 . . . cord-022526-j9kg00qf 2744 1 Although although IN cord-022526-j9kg00qf 2744 2 surgery surgery NN cord-022526-j9kg00qf 2744 3 has have VBZ cord-022526-j9kg00qf 2744 4 been be VBN cord-022526-j9kg00qf 2744 5 used use VBN cord-022526-j9kg00qf 2744 6 to to TO cord-022526-j9kg00qf 2744 7 relieve relieve VB cord-022526-j9kg00qf 2744 8 such such JJ cord-022526-j9kg00qf 2744 9 strictures stricture NNS cord-022526-j9kg00qf 2744 10 , , , cord-022526-j9kg00qf 2744 11 initial initial JJ cord-022526-j9kg00qf 2744 12 medical medical JJ cord-022526-j9kg00qf 2744 13 management management NN cord-022526-j9kg00qf 2744 14 is be VBZ cord-022526-j9kg00qf 2744 15 warranted warrant VBN cord-022526-j9kg00qf 2744 16 because because IN cord-022526-j9kg00qf 2744 17 strictures stricture NNS cord-022526-j9kg00qf 2744 18 may may MD cord-022526-j9kg00qf 2744 19 resolve resolve VB cord-022526-j9kg00qf 2744 20 with with IN cord-022526-j9kg00qf 2744 21 conservative conservative JJ cord-022526-j9kg00qf 2744 22 therapy therapy NN cord-022526-j9kg00qf 2744 23 , , , cord-022526-j9kg00qf 2744 24 and and CC cord-022526-j9kg00qf 2744 25 the the DT cord-022526-j9kg00qf 2744 26 esophagus esophagus NN cord-022526-j9kg00qf 2744 27 continues continue VBZ cord-022526-j9kg00qf 2744 28 to to TO cord-022526-j9kg00qf 2744 29 remodel remodel VB cord-022526-j9kg00qf 2744 30 for for IN cord-022526-j9kg00qf 2744 31 up up IN cord-022526-j9kg00qf 2744 32 to to TO cord-022526-j9kg00qf 2744 33 60 60 CD cord-022526-j9kg00qf 2744 34 days day NNS cord-022526-j9kg00qf 2744 35 following follow VBG cord-022526-j9kg00qf 2744 36 ulceration ulceration NN cord-022526-j9kg00qf 2744 37 . . . cord-022526-j9kg00qf 2745 1 In in IN cord-022526-j9kg00qf 2745 2 one one CD cord-022526-j9kg00qf 2745 3 report report NN cord-022526-j9kg00qf 2745 4 , , , cord-022526-j9kg00qf 2745 5 seven seven CD cord-022526-j9kg00qf 2745 6 horses horse NNS cord-022526-j9kg00qf 2745 7 with with IN cord-022526-j9kg00qf 2745 8 esophageal esophageal JJ cord-022526-j9kg00qf 2745 9 obstruction obstruction NN cord-022526-j9kg00qf 2745 10 - - HYPH cord-022526-j9kg00qf 2745 11 induced induce VBN cord-022526-j9kg00qf 2745 12 stricture stricture NN cord-022526-j9kg00qf 2745 13 were be VBD cord-022526-j9kg00qf 2745 14 treated treat VBN cord-022526-j9kg00qf 2745 15 conservatively conservatively RB cord-022526-j9kg00qf 2745 16 by by IN cord-022526-j9kg00qf 2745 17 feeding feed VBG cord-022526-j9kg00qf 2745 18 a a DT cord-022526-j9kg00qf 2745 19 slurry slurry NN cord-022526-j9kg00qf 2745 20 diet diet NN cord-022526-j9kg00qf 2745 21 and and CC cord-022526-j9kg00qf 2745 22 administering administer VBG cord-022526-j9kg00qf 2745 23 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2745 24 and and CC cord-022526-j9kg00qf 2745 25 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 2745 26 medications medication NNS cord-022526-j9kg00qf 2745 27 , , , cord-022526-j9kg00qf 2745 28 and and CC cord-022526-j9kg00qf 2745 29 five five CD cord-022526-j9kg00qf 2745 30 of of IN cord-022526-j9kg00qf 2745 31 seven seven CD cord-022526-j9kg00qf 2745 32 were be VBD cord-022526-j9kg00qf 2745 33 clinically clinically RB cord-022526-j9kg00qf 2745 34 normal normal JJ cord-022526-j9kg00qf 2745 35 within within IN cord-022526-j9kg00qf 2745 36 60 60 CD cord-022526-j9kg00qf 2745 37 days day NNS cord-022526-j9kg00qf 2745 38 . . . cord-022526-j9kg00qf 2746 1 35 35 CD cord-022526-j9kg00qf 2746 2 One one CD cord-022526-j9kg00qf 2746 3 of of IN cord-022526-j9kg00qf 2746 4 the the DT cord-022526-j9kg00qf 2746 5 five five CD cord-022526-j9kg00qf 2746 6 successfully successfully RB cord-022526-j9kg00qf 2746 7 treated treat VBN cord-022526-j9kg00qf 2746 8 horses horse NNS cord-022526-j9kg00qf 2746 9 had have VBD cord-022526-j9kg00qf 2746 10 a a DT cord-022526-j9kg00qf 2746 11 10-cm 10-cm CD cord-022526-j9kg00qf 2746 12 area area NN cord-022526-j9kg00qf 2746 13 of of IN cord-022526-j9kg00qf 2746 14 circumferential circumferential JJ cord-022526-j9kg00qf 2746 15 ulceration ulceration NN cord-022526-j9kg00qf 2746 16 , , , cord-022526-j9kg00qf 2746 17 suggesting suggest VBG cord-022526-j9kg00qf 2746 18 that that IN cord-022526-j9kg00qf 2746 19 the the DT cord-022526-j9kg00qf 2746 20 potential potential NN cord-022526-j9kg00qf 2746 21 exists exist VBZ cord-022526-j9kg00qf 2746 22 for for IN cord-022526-j9kg00qf 2746 23 extensive extensive JJ cord-022526-j9kg00qf 2746 24 mucosal mucosal JJ cord-022526-j9kg00qf 2746 25 injury injury NN cord-022526-j9kg00qf 2746 26 to to TO cord-022526-j9kg00qf 2746 27 resolve resolve VB cord-022526-j9kg00qf 2746 28 without without IN cord-022526-j9kg00qf 2746 29 permanent permanent JJ cord-022526-j9kg00qf 2746 30 stricture stricture NN cord-022526-j9kg00qf 2746 31 formation formation NN cord-022526-j9kg00qf 2746 32 . . . cord-022526-j9kg00qf 2747 1 If if IN cord-022526-j9kg00qf 2747 2 resolution resolution NN cord-022526-j9kg00qf 2747 3 of of IN cord-022526-j9kg00qf 2747 4 strictures stricture NNS cord-022526-j9kg00qf 2747 5 within within IN cord-022526-j9kg00qf 2747 6 60 60 CD cord-022526-j9kg00qf 2747 7 days day NNS cord-022526-j9kg00qf 2747 8 is be VBZ cord-022526-j9kg00qf 2747 9 insufficient insufficient JJ cord-022526-j9kg00qf 2747 10 , , , cord-022526-j9kg00qf 2747 11 one one PRP cord-022526-j9kg00qf 2747 12 should should MD cord-022526-j9kg00qf 2747 13 investigate investigate VB cord-022526-j9kg00qf 2747 14 other other JJ cord-022526-j9kg00qf 2747 15 methods method NNS cord-022526-j9kg00qf 2747 16 to to TO cord-022526-j9kg00qf 2747 17 increase increase VB cord-022526-j9kg00qf 2747 18 esophageal esophageal JJ cord-022526-j9kg00qf 2747 19 diameter diameter NN cord-022526-j9kg00qf 2747 20 . . . cord-022526-j9kg00qf 2748 1 Bougienage Bougienage NNP cord-022526-j9kg00qf 2748 2 has have VBZ cord-022526-j9kg00qf 2748 3 been be VBN cord-022526-j9kg00qf 2748 4 used use VBN cord-022526-j9kg00qf 2748 5 successfully successfully RB cord-022526-j9kg00qf 2748 6 in in IN cord-022526-j9kg00qf 2748 7 small small JJ cord-022526-j9kg00qf 2748 8 animal animal NN cord-022526-j9kg00qf 2748 9 patients patient NNS cord-022526-j9kg00qf 2748 10 and and CC cord-022526-j9kg00qf 2748 11 human human JJ cord-022526-j9kg00qf 2748 12 beings being NNS cord-022526-j9kg00qf 2748 13 . . . cord-022526-j9kg00qf 2749 1 The the DT cord-022526-j9kg00qf 2749 2 technique technique NN cord-022526-j9kg00qf 2749 3 involves involve VBZ cord-022526-j9kg00qf 2749 4 passage passage NN cord-022526-j9kg00qf 2749 5 of of IN cord-022526-j9kg00qf 2749 6 a a DT cord-022526-j9kg00qf 2749 7 tubular tubular JJ cord-022526-j9kg00qf 2749 8 dilatable dilatable NN cord-022526-j9kg00qf 2749 9 instrument instrument NN cord-022526-j9kg00qf 2749 10 down down IN cord-022526-j9kg00qf 2749 11 the the DT cord-022526-j9kg00qf 2749 12 esophagus esophagus NN cord-022526-j9kg00qf 2749 13 and and CC cord-022526-j9kg00qf 2749 14 stretching stretching NN cord-022526-j9kg00qf 2749 15 of of IN cord-022526-j9kg00qf 2749 16 the the DT cord-022526-j9kg00qf 2749 17 stricture stricture NN cord-022526-j9kg00qf 2749 18 . . . cord-022526-j9kg00qf 2750 1 One one PRP cord-022526-j9kg00qf 2750 2 may may MD cord-022526-j9kg00qf 2750 3 perform perform VB cord-022526-j9kg00qf 2750 4 the the DT cord-022526-j9kg00qf 2750 5 technique technique NN cord-022526-j9kg00qf 2750 6 by by IN cord-022526-j9kg00qf 2750 7 passing pass VBG cord-022526-j9kg00qf 2750 8 a a DT cord-022526-j9kg00qf 2750 9 nasogastric nasogastric NN cord-022526-j9kg00qf 2750 10 tube tube NN cord-022526-j9kg00qf 2750 11 with with IN cord-022526-j9kg00qf 2750 12 an an DT cord-022526-j9kg00qf 2750 13 inflatable inflatable JJ cord-022526-j9kg00qf 2750 14 cuff cuff NN cord-022526-j9kg00qf 2750 15 . . . cord-022526-j9kg00qf 2751 1 However however RB cord-022526-j9kg00qf 2751 2 , , , cord-022526-j9kg00qf 2751 3 one one PRP cord-022526-j9kg00qf 2751 4 has have VBZ cord-022526-j9kg00qf 2751 5 to to TO cord-022526-j9kg00qf 2751 6 perform perform VB cord-022526-j9kg00qf 2751 7 the the DT cord-022526-j9kg00qf 2751 8 procedure procedure NN cord-022526-j9kg00qf 2751 9 frequently frequently RB cord-022526-j9kg00qf 2751 10 to to TO cord-022526-j9kg00qf 2751 11 have have VB cord-022526-j9kg00qf 2751 12 any any DT cord-022526-j9kg00qf 2751 13 success success NN cord-022526-j9kg00qf 2751 14 , , , cord-022526-j9kg00qf 2751 15 and and CC cord-022526-j9kg00qf 2751 16 horses horse NNS cord-022526-j9kg00qf 2751 17 do do VBP cord-022526-j9kg00qf 2751 18 not not RB cord-022526-j9kg00qf 2751 19 tolerate tolerate VB cord-022526-j9kg00qf 2751 20 it -PRON- PRP cord-022526-j9kg00qf 2751 21 well well RB cord-022526-j9kg00qf 2751 22 . . . cord-022526-j9kg00qf 2752 1 36 36 CD cord-022526-j9kg00qf 2753 1 Alternatively alternatively RB cord-022526-j9kg00qf 2753 2 , , , cord-022526-j9kg00qf 2753 3 a a DT cord-022526-j9kg00qf 2753 4 number number NN cord-022526-j9kg00qf 2753 5 of of IN cord-022526-j9kg00qf 2753 6 surgical surgical JJ cord-022526-j9kg00qf 2753 7 techniques technique NNS cord-022526-j9kg00qf 2753 8 have have VBP cord-022526-j9kg00qf 2753 9 been be VBN cord-022526-j9kg00qf 2753 10 used use VBN cord-022526-j9kg00qf 2753 11 to to TO cord-022526-j9kg00qf 2753 12 resolve resolve VB cord-022526-j9kg00qf 2753 13 strictures stricture NNS cord-022526-j9kg00qf 2753 14 , , , cord-022526-j9kg00qf 2753 15 including include VBG cord-022526-j9kg00qf 2753 16 resection resection NN cord-022526-j9kg00qf 2753 17 and and CC cord-022526-j9kg00qf 2753 18 anastomosis anastomosis NN cord-022526-j9kg00qf 2753 19 , , , cord-022526-j9kg00qf 2753 20 38,39 38,39 CD cord-022526-j9kg00qf 2753 21 temporary temporary JJ cord-022526-j9kg00qf 2753 22 esophagostomy esophagostomy NN cord-022526-j9kg00qf 2753 23 with with IN cord-022526-j9kg00qf 2753 24 fenestration fenestration NN cord-022526-j9kg00qf 2753 25 of of IN cord-022526-j9kg00qf 2753 26 the the DT cord-022526-j9kg00qf 2753 27 stricture stricture NN cord-022526-j9kg00qf 2753 28 , , , cord-022526-j9kg00qf 2753 29 37 37 CD cord-022526-j9kg00qf 2753 30 esophagomyotomy esophagomyotomy NN cord-022526-j9kg00qf 2753 31 for for IN cord-022526-j9kg00qf 2753 32 strictures stricture NNS cord-022526-j9kg00qf 2753 33 of of IN cord-022526-j9kg00qf 2753 34 the the DT cord-022526-j9kg00qf 2753 35 muscularis muscularis NNP cord-022526-j9kg00qf 2753 36 and and CC cord-022526-j9kg00qf 2753 37 adventitia adventitia NN cord-022526-j9kg00qf 2753 38 , , , cord-022526-j9kg00qf 2753 39 40 40 CD cord-022526-j9kg00qf 2753 40 , , , cord-022526-j9kg00qf 2753 41 41 41 CD cord-022526-j9kg00qf 2753 42 or or CC cord-022526-j9kg00qf 2753 43 patch patch NN cord-022526-j9kg00qf 2753 44 grafting grafting NN cord-022526-j9kg00qf 2753 45 with with IN cord-022526-j9kg00qf 2753 46 local local JJ cord-022526-j9kg00qf 2753 47 musculature musculature NN cord-022526-j9kg00qf 2753 48 . . . cord-022526-j9kg00qf 2754 1 42 42 CD cord-022526-j9kg00qf 2755 1 However however RB cord-022526-j9kg00qf 2755 2 , , , cord-022526-j9kg00qf 2755 3 such such JJ cord-022526-j9kg00qf 2755 4 surgeries surgery NNS cord-022526-j9kg00qf 2755 5 are be VBP cord-022526-j9kg00qf 2755 6 fraught fraught JJ cord-022526-j9kg00qf 2755 7 with with IN cord-022526-j9kg00qf 2755 8 complications complication NNS cord-022526-j9kg00qf 2755 9 , , , cord-022526-j9kg00qf 2755 10 largely largely RB cord-022526-j9kg00qf 2755 11 because because IN cord-022526-j9kg00qf 2755 12 of of IN cord-022526-j9kg00qf 2755 13 the the DT cord-022526-j9kg00qf 2755 14 propensity propensity NN cord-022526-j9kg00qf 2755 15 of of IN cord-022526-j9kg00qf 2755 16 the the DT cord-022526-j9kg00qf 2755 17 traumatized traumatize VBN cord-022526-j9kg00qf 2755 18 esophagus esophagu NNS cord-022526-j9kg00qf 2755 19 to to IN cord-022526-j9kg00qf 2755 20 restricture restricture NN cord-022526-j9kg00qf 2755 21 . . . cord-022526-j9kg00qf 2756 1 3 3 CD cord-022526-j9kg00qf 2756 2 , , , cord-022526-j9kg00qf 2756 3 35 35 CD cord-022526-j9kg00qf 2757 1 The the DT cord-022526-j9kg00qf 2757 2 esophagus esophagus NN cord-022526-j9kg00qf 2757 3 lacks lack VBZ cord-022526-j9kg00qf 2757 4 a a DT cord-022526-j9kg00qf 2757 5 serosal serosal NN cord-022526-j9kg00qf 2757 6 layer layer NN cord-022526-j9kg00qf 2757 7 and and CC cord-022526-j9kg00qf 2757 8 does do VBZ cord-022526-j9kg00qf 2757 9 not not RB cord-022526-j9kg00qf 2757 10 rapidly rapidly RB cord-022526-j9kg00qf 2757 11 form form VB cord-022526-j9kg00qf 2757 12 a a DT cord-022526-j9kg00qf 2757 13 fibrin fibrin NN cord-022526-j9kg00qf 2757 14 seal seal NN cord-022526-j9kg00qf 2757 15 as as IN cord-022526-j9kg00qf 2757 16 does do VBZ cord-022526-j9kg00qf 2757 17 the the DT cord-022526-j9kg00qf 2757 18 remainder remainder NN cord-022526-j9kg00qf 2757 19 of of IN cord-022526-j9kg00qf 2757 20 the the DT cord-022526-j9kg00qf 2757 21 intestinal intestinal JJ cord-022526-j9kg00qf 2757 22 tract tract NN cord-022526-j9kg00qf 2757 23 , , , cord-022526-j9kg00qf 2757 24 so so RB cord-022526-j9kg00qf 2757 25 anastomoses anastomosis NNS cord-022526-j9kg00qf 2757 26 tend tend VBP cord-022526-j9kg00qf 2757 27 to to TO cord-022526-j9kg00qf 2757 28 leak leak VB cord-022526-j9kg00qf 2757 29 . . . cord-022526-j9kg00qf 2758 1 38 38 CD cord-022526-j9kg00qf 2759 1 In in IN cord-022526-j9kg00qf 2759 2 addition addition NN cord-022526-j9kg00qf 2759 3 , , , cord-022526-j9kg00qf 2759 4 tension tension NN cord-022526-j9kg00qf 2759 5 on on IN cord-022526-j9kg00qf 2759 6 the the DT cord-022526-j9kg00qf 2759 7 esophagus esophagus NN cord-022526-j9kg00qf 2759 8 during during IN cord-022526-j9kg00qf 2759 9 swallowing swallowing NN cord-022526-j9kg00qf 2759 10 and and CC cord-022526-j9kg00qf 2759 11 movement movement NN cord-022526-j9kg00qf 2759 12 of of IN cord-022526-j9kg00qf 2759 13 the the DT cord-022526-j9kg00qf 2759 14 neck neck NN cord-022526-j9kg00qf 2759 15 impairs impair VBZ cord-022526-j9kg00qf 2759 16 healing healing NN cord-022526-j9kg00qf 2759 17 of of IN cord-022526-j9kg00qf 2759 18 anastomoses anastomosis NNS cord-022526-j9kg00qf 2759 19 . . . cord-022526-j9kg00qf 2760 1 37 37 CD cord-022526-j9kg00qf 2760 2 , , , cord-022526-j9kg00qf 2760 3 39 39 CD cord-022526-j9kg00qf 2761 1 In in IN cord-022526-j9kg00qf 2761 2 spite spite NN cord-022526-j9kg00qf 2761 3 of of IN cord-022526-j9kg00qf 2761 4 these these DT cord-022526-j9kg00qf 2761 5 difficulties difficulty NNS cord-022526-j9kg00qf 2761 6 , , , cord-022526-j9kg00qf 2761 7 the the DT cord-022526-j9kg00qf 2761 8 long long JJ cord-022526-j9kg00qf 2761 9 - - HYPH cord-022526-j9kg00qf 2761 10 term term NN cord-022526-j9kg00qf 2761 11 prognosis prognosis NN cord-022526-j9kg00qf 2761 12 for for IN cord-022526-j9kg00qf 2761 13 horses horse NNS cord-022526-j9kg00qf 2761 14 with with IN cord-022526-j9kg00qf 2761 15 chronic chronic JJ cord-022526-j9kg00qf 2761 16 esophageal esophageal JJ cord-022526-j9kg00qf 2761 17 strictures stricture NNS cord-022526-j9kg00qf 2761 18 treated treat VBN cord-022526-j9kg00qf 2761 19 surgically surgically RB cord-022526-j9kg00qf 2761 20 is be VBZ cord-022526-j9kg00qf 2761 21 better well JJR cord-022526-j9kg00qf 2761 22 than than IN cord-022526-j9kg00qf 2761 23 for for IN cord-022526-j9kg00qf 2761 24 those those DT cord-022526-j9kg00qf 2761 25 treated treat VBN cord-022526-j9kg00qf 2761 26 nonsurgically nonsurgically RB cord-022526-j9kg00qf 2761 27 . . . cord-022526-j9kg00qf 2762 1 3 3 LS cord-022526-j9kg00qf 2763 1 Two two CD cord-022526-j9kg00qf 2763 2 types type NNS cord-022526-j9kg00qf 2763 3 of of IN cord-022526-j9kg00qf 2763 4 diverticula diverticulum NNS cord-022526-j9kg00qf 2763 5 are be VBP cord-022526-j9kg00qf 2763 6 traction traction NN cord-022526-j9kg00qf 2763 7 ( ( -LRB- cord-022526-j9kg00qf 2763 8 true true JJ cord-022526-j9kg00qf 2763 9 ) ) -RRB- cord-022526-j9kg00qf 2763 10 diverticula diverticula NN cord-022526-j9kg00qf 2763 11 and and CC cord-022526-j9kg00qf 2763 12 pulsion pulsion NN cord-022526-j9kg00qf 2763 13 ( ( -LRB- cord-022526-j9kg00qf 2763 14 false false JJ cord-022526-j9kg00qf 2763 15 ) ) -RRB- cord-022526-j9kg00qf 2763 16 diverticula diverticula NN cord-022526-j9kg00qf 2763 17 . . . cord-022526-j9kg00qf 2764 1 Traction traction NN cord-022526-j9kg00qf 2764 2 diverticula diverticula NN cord-022526-j9kg00qf 2764 3 result result NN cord-022526-j9kg00qf 2764 4 from from IN cord-022526-j9kg00qf 2764 5 wounding wounding NN cord-022526-j9kg00qf 2764 6 and and CC cord-022526-j9kg00qf 2764 7 subsequent subsequent JJ cord-022526-j9kg00qf 2764 8 contraction contraction NN cord-022526-j9kg00qf 2764 9 of of IN cord-022526-j9kg00qf 2764 10 periesophageal periesophageal JJ cord-022526-j9kg00qf 2764 11 tissues tissue NNS cord-022526-j9kg00qf 2764 12 , , , cord-022526-j9kg00qf 2764 13 with with IN cord-022526-j9kg00qf 2764 14 resultant resultant JJ cord-022526-j9kg00qf 2764 15 tenting tenting NN cord-022526-j9kg00qf 2764 16 of of IN cord-022526-j9kg00qf 2764 17 the the DT cord-022526-j9kg00qf 2764 18 wall wall NN cord-022526-j9kg00qf 2764 19 of of IN cord-022526-j9kg00qf 2764 20 the the DT cord-022526-j9kg00qf 2764 21 esophagus esophagus NN cord-022526-j9kg00qf 2764 22 . . . cord-022526-j9kg00qf 2765 1 Pulsion Pulsion NNP cord-022526-j9kg00qf 2765 2 diverticula diverticulum NNS cord-022526-j9kg00qf 2765 3 arise arise VBP cord-022526-j9kg00qf 2765 4 from from IN cord-022526-j9kg00qf 2765 5 protrusion protrusion NN cord-022526-j9kg00qf 2765 6 of of IN cord-022526-j9kg00qf 2765 7 esophageal esophageal JJ cord-022526-j9kg00qf 2765 8 mucosa mucosa NN cord-022526-j9kg00qf 2765 9 through through IN cord-022526-j9kg00qf 2765 10 defects defect NNS cord-022526-j9kg00qf 2765 11 in in IN cord-022526-j9kg00qf 2765 12 the the DT cord-022526-j9kg00qf 2765 13 muscular muscular JJ cord-022526-j9kg00qf 2765 14 wall wall NN cord-022526-j9kg00qf 2765 15 of of IN cord-022526-j9kg00qf 2765 16 the the DT cord-022526-j9kg00qf 2765 17 esophagus esophagus NN cord-022526-j9kg00qf 2765 18 and and CC cord-022526-j9kg00qf 2765 19 usually usually RB cord-022526-j9kg00qf 2765 20 result result VBP cord-022526-j9kg00qf 2765 21 from from IN cord-022526-j9kg00qf 2765 22 trauma trauma NN cord-022526-j9kg00qf 2765 23 or or CC cord-022526-j9kg00qf 2765 24 acute acute JJ cord-022526-j9kg00qf 2765 25 changes change NNS cord-022526-j9kg00qf 2765 26 in in IN cord-022526-j9kg00qf 2765 27 intraluminal intraluminal JJ cord-022526-j9kg00qf 2765 28 pressure pressure NN cord-022526-j9kg00qf 2765 29 . . . cord-022526-j9kg00qf 2766 1 36 36 CD cord-022526-j9kg00qf 2766 2 Traction traction NN cord-022526-j9kg00qf 2766 3 diverticula diverticula NN cord-022526-j9kg00qf 2766 4 appear appear VBP cord-022526-j9kg00qf 2766 5 as as IN cord-022526-j9kg00qf 2766 6 a a DT cord-022526-j9kg00qf 2766 7 dilation dilation NN cord-022526-j9kg00qf 2766 8 with with IN cord-022526-j9kg00qf 2766 9 a a DT cord-022526-j9kg00qf 2766 10 broad broad JJ cord-022526-j9kg00qf 2766 11 neck neck NN cord-022526-j9kg00qf 2766 12 on on IN cord-022526-j9kg00qf 2766 13 contrast contrast NN cord-022526-j9kg00qf 2766 14 esophagography esophagography NN cord-022526-j9kg00qf 2766 15 , , , cord-022526-j9kg00qf 2766 16 whereas whereas IN cord-022526-j9kg00qf 2766 17 pulsion pulsion NN cord-022526-j9kg00qf 2766 18 diverticula diverticulum NNS cord-022526-j9kg00qf 2766 19 typically typically RB cord-022526-j9kg00qf 2766 20 have have VBP cord-022526-j9kg00qf 2766 21 a a DT cord-022526-j9kg00qf 2766 22 flask flask NN cord-022526-j9kg00qf 2766 23 shape shape NN cord-022526-j9kg00qf 2766 24 with with IN cord-022526-j9kg00qf 2766 25 a a DT cord-022526-j9kg00qf 2766 26 small small JJ cord-022526-j9kg00qf 2766 27 neck neck NN cord-022526-j9kg00qf 2766 28 on on IN cord-022526-j9kg00qf 2766 29 an an DT cord-022526-j9kg00qf 2766 30 esophagram esophagram NN cord-022526-j9kg00qf 2766 31 ( ( -LRB- cord-022526-j9kg00qf 2766 32 see see VB cord-022526-j9kg00qf 2766 33 Figure Figure NNP cord-022526-j9kg00qf 2766 34 13 13 CD cord-022526-j9kg00qf 2766 35 .9 .9 CD cord-022526-j9kg00qf 2766 36 - - SYM cord-022526-j9kg00qf 2766 37 2 2 CD cord-022526-j9kg00qf 2766 38 ) ) -RRB- cord-022526-j9kg00qf 2766 39 . . . cord-022526-j9kg00qf 2767 1 10 10 CD cord-022526-j9kg00qf 2767 2 , , , cord-022526-j9kg00qf 2767 3 43 43 CD cord-022526-j9kg00qf 2768 1 Although although IN cord-022526-j9kg00qf 2768 2 traction traction NN cord-022526-j9kg00qf 2768 3 diverticula diverticula NN cord-022526-j9kg00qf 2768 4 are be VBP cord-022526-j9kg00qf 2768 5 usually usually RB cord-022526-j9kg00qf 2768 6 asymptomatic asymptomatic JJ cord-022526-j9kg00qf 2768 7 and and CC cord-022526-j9kg00qf 2768 8 of of IN cord-022526-j9kg00qf 2768 9 little little JJ cord-022526-j9kg00qf 2768 10 clinical clinical JJ cord-022526-j9kg00qf 2768 11 significance significance NN cord-022526-j9kg00qf 2768 12 , , , cord-022526-j9kg00qf 2768 13 pulsion pulsion NN cord-022526-j9kg00qf 2768 14 diverticula diverticula NN cord-022526-j9kg00qf 2768 15 may may MD cord-022526-j9kg00qf 2768 16 fill fill VB cord-022526-j9kg00qf 2768 17 with with IN cord-022526-j9kg00qf 2768 18 feed feed NN cord-022526-j9kg00qf 2768 19 material material NN cord-022526-j9kg00qf 2768 20 , , , cord-022526-j9kg00qf 2768 21 ultimately ultimately RB cord-022526-j9kg00qf 2768 22 leading lead VBG cord-022526-j9kg00qf 2768 23 to to IN cord-022526-j9kg00qf 2768 24 esophageal esophageal JJ cord-022526-j9kg00qf 2768 25 obstruction obstruction NN cord-022526-j9kg00qf 2768 26 . . . cord-022526-j9kg00qf 2769 1 [ [ -LRB- cord-022526-j9kg00qf 2769 2 43 43 CD cord-022526-j9kg00qf 2769 3 ] ] -RRB- cord-022526-j9kg00qf 2769 4 [ [ -LRB- cord-022526-j9kg00qf 2769 5 44 44 CD cord-022526-j9kg00qf 2769 6 ] ] -RRB- cord-022526-j9kg00qf 2770 1 [ [ -LRB- cord-022526-j9kg00qf 2770 2 45 45 CD cord-022526-j9kg00qf 2770 3 ] ] -RRB- cord-022526-j9kg00qf 2771 1 A a DT cord-022526-j9kg00qf 2771 2 movable movable JJ cord-022526-j9kg00qf 2771 3 mass mass NN cord-022526-j9kg00qf 2771 4 in in IN cord-022526-j9kg00qf 2771 5 the the DT cord-022526-j9kg00qf 2771 6 midcervical midcervical JJ cord-022526-j9kg00qf 2771 7 region region NN cord-022526-j9kg00qf 2771 8 may may MD cord-022526-j9kg00qf 2771 9 be be VB cord-022526-j9kg00qf 2771 10 noticeable noticeable JJ cord-022526-j9kg00qf 2771 11 before before IN cord-022526-j9kg00qf 2771 12 onset onset NN cord-022526-j9kg00qf 2771 13 of of IN cord-022526-j9kg00qf 2771 14 complete complete JJ cord-022526-j9kg00qf 2771 15 obstruction obstruction NN cord-022526-j9kg00qf 2771 16 . . . cord-022526-j9kg00qf 2772 1 36 36 CD cord-022526-j9kg00qf 2772 2 Pulsion Pulsion NNP cord-022526-j9kg00qf 2772 3 diverticula diverticulum NNS cord-022526-j9kg00qf 2772 4 may may MD cord-022526-j9kg00qf 2772 5 be be VB cord-022526-j9kg00qf 2772 6 corrected correct VBN cord-022526-j9kg00qf 2772 7 surgically surgically RB cord-022526-j9kg00qf 2772 8 by by IN cord-022526-j9kg00qf 2772 9 inverting invert VBG cord-022526-j9kg00qf 2772 10 or or CC cord-022526-j9kg00qf 2772 11 resecting resect VBG cord-022526-j9kg00qf 2772 12 prolapsed prolapsed JJ cord-022526-j9kg00qf 2772 13 mucosa mucosa NN cord-022526-j9kg00qf 2772 14 and and CC cord-022526-j9kg00qf 2772 15 closing close VBG cord-022526-j9kg00qf 2772 16 the the DT cord-022526-j9kg00qf 2772 17 defect defect NN cord-022526-j9kg00qf 2772 18 in in IN cord-022526-j9kg00qf 2772 19 the the DT cord-022526-j9kg00qf 2772 20 wall wall NN cord-022526-j9kg00qf 2772 21 of of IN cord-022526-j9kg00qf 2772 22 the the DT cord-022526-j9kg00qf 2772 23 esophagus esophagus NN cord-022526-j9kg00qf 2772 24 . . . cord-022526-j9kg00qf 2773 1 10 10 CD cord-022526-j9kg00qf 2773 2 , , , cord-022526-j9kg00qf 2773 3 43 43 CD cord-022526-j9kg00qf 2773 4 , , , cord-022526-j9kg00qf 2773 5 45 45 CD cord-022526-j9kg00qf 2773 6 Inversion inversion NN cord-022526-j9kg00qf 2773 7 of of IN cord-022526-j9kg00qf 2773 8 excessive excessive JJ cord-022526-j9kg00qf 2773 9 mucosa mucosa NN cord-022526-j9kg00qf 2773 10 may may MD cord-022526-j9kg00qf 2773 11 reduce reduce VB cord-022526-j9kg00qf 2773 12 the the DT cord-022526-j9kg00qf 2773 13 diameter diameter NN cord-022526-j9kg00qf 2773 14 of of IN cord-022526-j9kg00qf 2773 15 the the DT cord-022526-j9kg00qf 2773 16 esophageal esophageal JJ cord-022526-j9kg00qf 2773 17 lumen lumen NN cord-022526-j9kg00qf 2773 18 and and CC cord-022526-j9kg00qf 2773 19 predispose predispose VB cord-022526-j9kg00qf 2773 20 horses horse NNS cord-022526-j9kg00qf 2773 21 to to TO cord-022526-j9kg00qf 2773 22 esophageal esophageal JJ cord-022526-j9kg00qf 2773 23 obstruction obstruction NN cord-022526-j9kg00qf 2773 24 and and CC cord-022526-j9kg00qf 2773 25 therefore therefore RB cord-022526-j9kg00qf 2773 26 should should MD cord-022526-j9kg00qf 2773 27 be be VB cord-022526-j9kg00qf 2773 28 reserved reserve VBN cord-022526-j9kg00qf 2773 29 for for IN cord-022526-j9kg00qf 2773 30 small small JJ cord-022526-j9kg00qf 2773 31 diverticula diverticulum NNS cord-022526-j9kg00qf 2773 32 . . . cord-022526-j9kg00qf 2774 1 10 10 CD cord-022526-j9kg00qf 2774 2 Congenital congenital JJ cord-022526-j9kg00qf 2774 3 disorders disorder NNS cord-022526-j9kg00qf 2774 4 of of IN cord-022526-j9kg00qf 2774 5 the the DT cord-022526-j9kg00qf 2774 6 esophagus esophagus NN cord-022526-j9kg00qf 2774 7 are be VBP cord-022526-j9kg00qf 2774 8 rare rare JJ cord-022526-j9kg00qf 2774 9 . . . cord-022526-j9kg00qf 2775 1 Reported reported JJ cord-022526-j9kg00qf 2775 2 congenital congenital JJ cord-022526-j9kg00qf 2775 3 abnormalities abnormality NNS cord-022526-j9kg00qf 2775 4 include include VBP cord-022526-j9kg00qf 2775 5 congenital congenital JJ cord-022526-j9kg00qf 2775 6 stenosis stenosis NN cord-022526-j9kg00qf 2775 7 , , , cord-022526-j9kg00qf 2775 8 46 46 CD cord-022526-j9kg00qf 2775 9 persistent persistent JJ cord-022526-j9kg00qf 2775 10 right right JJ cord-022526-j9kg00qf 2775 11 aortic aortic JJ cord-022526-j9kg00qf 2775 12 arch arch NN cord-022526-j9kg00qf 2775 13 , , , cord-022526-j9kg00qf 2775 14 8 8 CD cord-022526-j9kg00qf 2775 15 esophageal esophageal JJ cord-022526-j9kg00qf 2775 16 duplication duplication NN cord-022526-j9kg00qf 2775 17 cysts cyst NNS cord-022526-j9kg00qf 2775 18 , , , cord-022526-j9kg00qf 2775 19 [ [ -LRB- cord-022526-j9kg00qf 2775 20 47 47 CD cord-022526-j9kg00qf 2775 21 ] ] -RRB- cord-022526-j9kg00qf 2775 22 [ [ -LRB- cord-022526-j9kg00qf 2775 23 48 48 CD cord-022526-j9kg00qf 2775 24 ] ] -RRB- cord-022526-j9kg00qf 2775 25 [ [ -LRB- cord-022526-j9kg00qf 2775 26 49 49 CD cord-022526-j9kg00qf 2775 27 ] ] -RRB- cord-022526-j9kg00qf 2775 28 intramural intramural JJ cord-022526-j9kg00qf 2775 29 inclusion inclusion NN cord-022526-j9kg00qf 2775 30 cysts cyst NNS cord-022526-j9kg00qf 2775 31 , , , cord-022526-j9kg00qf 2775 32 9 9 CD cord-022526-j9kg00qf 2775 33 , , , cord-022526-j9kg00qf 2775 34 50 50 CD cord-022526-j9kg00qf 2775 35 and and CC cord-022526-j9kg00qf 2775 36 idiopathic idiopathic JJ cord-022526-j9kg00qf 2775 37 megaesophagus megaesophagus NNP cord-022526-j9kg00qf 2775 38 . . . cord-022526-j9kg00qf 2776 1 28 28 CD cord-022526-j9kg00qf 2776 2 , , , cord-022526-j9kg00qf 2776 3 30 30 CD cord-022526-j9kg00qf 2776 4 , , , cord-022526-j9kg00qf 2776 5 31 31 CD cord-022526-j9kg00qf 2777 1 In in IN cord-022526-j9kg00qf 2777 2 the the DT cord-022526-j9kg00qf 2777 3 one one CD cord-022526-j9kg00qf 2777 4 report report NN cord-022526-j9kg00qf 2777 5 of of IN cord-022526-j9kg00qf 2777 6 congenital congenital JJ cord-022526-j9kg00qf 2777 7 stenosis stenosis NN cord-022526-j9kg00qf 2777 8 , , , cord-022526-j9kg00qf 2777 9 double double JJ cord-022526-j9kg00qf 2777 10 - - HYPH cord-022526-j9kg00qf 2777 11 contrast contrast NN cord-022526-j9kg00qf 2777 12 radiography radiography NN cord-022526-j9kg00qf 2777 13 revealed reveal VBD cord-022526-j9kg00qf 2777 14 concentric concentric JJ cord-022526-j9kg00qf 2777 15 narrowing narrowing NN cord-022526-j9kg00qf 2777 16 of of IN cord-022526-j9kg00qf 2777 17 the the DT cord-022526-j9kg00qf 2777 18 thoracic thoracic JJ cord-022526-j9kg00qf 2777 19 esophagus esophagus NN cord-022526-j9kg00qf 2777 20 in in IN cord-022526-j9kg00qf 2777 21 the the DT cord-022526-j9kg00qf 2777 22 absence absence NN cord-022526-j9kg00qf 2777 23 of of IN cord-022526-j9kg00qf 2777 24 any any DT cord-022526-j9kg00qf 2777 25 vascular vascular JJ cord-022526-j9kg00qf 2777 26 abnormalities abnormality NNS cord-022526-j9kg00qf 2777 27 at at IN cord-022526-j9kg00qf 2777 28 the the DT cord-022526-j9kg00qf 2777 29 base base NN cord-022526-j9kg00qf 2777 30 of of IN cord-022526-j9kg00qf 2777 31 the the DT cord-022526-j9kg00qf 2777 32 heart heart NN cord-022526-j9kg00qf 2777 33 . . . cord-022526-j9kg00qf 2778 1 Successful successful JJ cord-022526-j9kg00qf 2778 2 treatment treatment NN cord-022526-j9kg00qf 2778 3 included include VBD cord-022526-j9kg00qf 2778 4 having have VBG cord-022526-j9kg00qf 2778 5 the the DT cord-022526-j9kg00qf 2778 6 foal foal NN cord-022526-j9kg00qf 2778 7 stand stand VB cord-022526-j9kg00qf 2778 8 with with IN cord-022526-j9kg00qf 2778 9 the the DT cord-022526-j9kg00qf 2778 10 forelimbs forelimb NNS cord-022526-j9kg00qf 2778 11 elevated elevate VBN cord-022526-j9kg00qf 2778 12 off off IN cord-022526-j9kg00qf 2778 13 the the DT cord-022526-j9kg00qf 2778 14 ground ground NN cord-022526-j9kg00qf 2778 15 following follow VBG cord-022526-j9kg00qf 2778 16 each each DT cord-022526-j9kg00qf 2778 17 feeding feeding NN cord-022526-j9kg00qf 2778 18 . . . cord-022526-j9kg00qf 2779 1 46 46 CD cord-022526-j9kg00qf 2780 1 Persistent persistent JJ cord-022526-j9kg00qf 2780 2 right right JJ cord-022526-j9kg00qf 2780 3 aortic aortic JJ cord-022526-j9kg00qf 2780 4 arch arch NN cord-022526-j9kg00qf 2780 5 is be VBZ cord-022526-j9kg00qf 2780 6 a a DT cord-022526-j9kg00qf 2780 7 congenital congenital JJ cord-022526-j9kg00qf 2780 8 anomaly anomaly NN cord-022526-j9kg00qf 2780 9 in in IN cord-022526-j9kg00qf 2780 10 which which WDT cord-022526-j9kg00qf 2780 11 the the DT cord-022526-j9kg00qf 2780 12 right right JJ cord-022526-j9kg00qf 2780 13 fourth fourth JJ cord-022526-j9kg00qf 2780 14 aortic aortic JJ cord-022526-j9kg00qf 2780 15 arch arch NN cord-022526-j9kg00qf 2780 16 becomes become VBZ cord-022526-j9kg00qf 2780 17 the the DT cord-022526-j9kg00qf 2780 18 definitive definitive JJ cord-022526-j9kg00qf 2780 19 aorta aorta NN cord-022526-j9kg00qf 2780 20 instead instead RB cord-022526-j9kg00qf 2780 21 of of IN cord-022526-j9kg00qf 2780 22 the the DT cord-022526-j9kg00qf 2780 23 left left JJ cord-022526-j9kg00qf 2780 24 aortic aortic JJ cord-022526-j9kg00qf 2780 25 arch arch NN cord-022526-j9kg00qf 2780 26 , , , cord-022526-j9kg00qf 2780 27 which which WDT cord-022526-j9kg00qf 2780 28 results result VBZ cord-022526-j9kg00qf 2780 29 in in IN cord-022526-j9kg00qf 2780 30 constriction constriction NN cord-022526-j9kg00qf 2780 31 of of IN cord-022526-j9kg00qf 2780 32 the the DT cord-022526-j9kg00qf 2780 33 esophagus esophagus NN cord-022526-j9kg00qf 2780 34 by by IN cord-022526-j9kg00qf 2780 35 the the DT cord-022526-j9kg00qf 2780 36 ligamentum ligamentum NNP cord-022526-j9kg00qf 2780 37 arteriosum arteriosum NN cord-022526-j9kg00qf 2780 38 as as IN cord-022526-j9kg00qf 2780 39 it -PRON- PRP cord-022526-j9kg00qf 2780 40 extends extend VBZ cord-022526-j9kg00qf 2780 41 between between IN cord-022526-j9kg00qf 2780 42 the the DT cord-022526-j9kg00qf 2780 43 anomalous anomalous JJ cord-022526-j9kg00qf 2780 44 right right JJ cord-022526-j9kg00qf 2780 45 aorta aorta NN cord-022526-j9kg00qf 2780 46 and and CC cord-022526-j9kg00qf 2780 47 the the DT cord-022526-j9kg00qf 2780 48 left left JJ cord-022526-j9kg00qf 2780 49 pulmonary pulmonary JJ cord-022526-j9kg00qf 2780 50 artery artery NN cord-022526-j9kg00qf 2780 51 . . . cord-022526-j9kg00qf 2781 1 Clinical clinical JJ cord-022526-j9kg00qf 2781 2 signs sign NNS cord-022526-j9kg00qf 2781 3 may may MD cord-022526-j9kg00qf 2781 4 include include VB cord-022526-j9kg00qf 2781 5 those those DT cord-022526-j9kg00qf 2781 6 associated associate VBN cord-022526-j9kg00qf 2781 7 with with IN cord-022526-j9kg00qf 2781 8 esophageal esophageal JJ cord-022526-j9kg00qf 2781 9 ( ( -LRB- cord-022526-j9kg00qf 2781 10 postpharyngeal postpharyngeal NN cord-022526-j9kg00qf 2781 11 ) ) -RRB- cord-022526-j9kg00qf 2781 12 dysphagia dysphagia NNP cord-022526-j9kg00qf 2781 13 , , , cord-022526-j9kg00qf 2781 14 drooling drool VBG cord-022526-j9kg00qf 2781 15 , , , cord-022526-j9kg00qf 2781 16 and and CC cord-022526-j9kg00qf 2781 17 distention distention NN cord-022526-j9kg00qf 2781 18 of of IN cord-022526-j9kg00qf 2781 19 the the DT cord-022526-j9kg00qf 2781 20 cervical cervical JJ cord-022526-j9kg00qf 2781 21 esophagus esophagus NN cord-022526-j9kg00qf 2781 22 resulting result VBG cord-022526-j9kg00qf 2781 23 from from IN cord-022526-j9kg00qf 2781 24 partial partial JJ cord-022526-j9kg00qf 2781 25 obstruction obstruction NN cord-022526-j9kg00qf 2781 26 of of IN cord-022526-j9kg00qf 2781 27 the the DT cord-022526-j9kg00qf 2781 28 thoracic thoracic JJ cord-022526-j9kg00qf 2781 29 esophagus esophagus NN cord-022526-j9kg00qf 2781 30 . . . cord-022526-j9kg00qf 2782 1 8 8 CD cord-022526-j9kg00qf 2782 2 , , , cord-022526-j9kg00qf 2782 3 51 51 CD cord-022526-j9kg00qf 2782 4 Endoscopic endoscopic JJ cord-022526-j9kg00qf 2782 5 examination examination NN cord-022526-j9kg00qf 2782 6 typically typically RB cord-022526-j9kg00qf 2782 7 reveals reveal VBZ cord-022526-j9kg00qf 2782 8 dilation dilation NN cord-022526-j9kg00qf 2782 9 of of IN cord-022526-j9kg00qf 2782 10 the the DT cord-022526-j9kg00qf 2782 11 esophagus esophagus NN cord-022526-j9kg00qf 2782 12 cranial cranial NN cord-022526-j9kg00qf 2782 13 to to IN cord-022526-j9kg00qf 2782 14 the the DT cord-022526-j9kg00qf 2782 15 obstruction obstruction NN cord-022526-j9kg00qf 2782 16 SECTION section NN cord-022526-j9kg00qf 2782 17 13.9 13.9 CD cord-022526-j9kg00qf 2782 18 Esophageal esophageal JJ cord-022526-j9kg00qf 2782 19 Diseases disease NNS cord-022526-j9kg00qf 2782 20 with with IN cord-022526-j9kg00qf 2782 21 evidence evidence NN cord-022526-j9kg00qf 2782 22 of of IN cord-022526-j9kg00qf 2782 23 diffuse diffuse JJ cord-022526-j9kg00qf 2782 24 esophagitis esophagitis NN cord-022526-j9kg00qf 2782 25 . . . cord-022526-j9kg00qf 2783 1 Successful successful JJ cord-022526-j9kg00qf 2783 2 surgical surgical JJ cord-022526-j9kg00qf 2783 3 treatment treatment NN cord-022526-j9kg00qf 2783 4 of of IN cord-022526-j9kg00qf 2783 5 persistent persistent JJ cord-022526-j9kg00qf 2783 6 right right JJ cord-022526-j9kg00qf 2783 7 aortic aortic JJ cord-022526-j9kg00qf 2783 8 arch arch NN cord-022526-j9kg00qf 2783 9 has have VBZ cord-022526-j9kg00qf 2783 10 been be VBN cord-022526-j9kg00qf 2783 11 reported report VBN cord-022526-j9kg00qf 2783 12 in in IN cord-022526-j9kg00qf 2783 13 one one CD cord-022526-j9kg00qf 2783 14 foal foal NN cord-022526-j9kg00qf 2783 15 . . . cord-022526-j9kg00qf 2784 1 51 51 CD cord-022526-j9kg00qf 2784 2 Esophageal esophageal JJ cord-022526-j9kg00qf 2784 3 duplication duplication NN cord-022526-j9kg00qf 2784 4 cysts cyst NNS cord-022526-j9kg00qf 2784 5 and and CC cord-022526-j9kg00qf 2784 6 intramural intramural JJ cord-022526-j9kg00qf 2784 7 inclusion inclusion NN cord-022526-j9kg00qf 2784 8 cysts cyst NNS cord-022526-j9kg00qf 2784 9 cause cause VBP cord-022526-j9kg00qf 2784 10 typical typical JJ cord-022526-j9kg00qf 2784 11 signs sign NNS cord-022526-j9kg00qf 2784 12 of of IN cord-022526-j9kg00qf 2784 13 esophageal esophageal JJ cord-022526-j9kg00qf 2784 14 obstruction obstruction NN cord-022526-j9kg00qf 2784 15 , , , cord-022526-j9kg00qf 2784 16 including include VBG cord-022526-j9kg00qf 2784 17 salivation salivation NN cord-022526-j9kg00qf 2784 18 , , , cord-022526-j9kg00qf 2784 19 esophageal esophageal JJ cord-022526-j9kg00qf 2784 20 dysphagia dysphagia NN cord-022526-j9kg00qf 2784 21 , , , cord-022526-j9kg00qf 2784 22 and and CC cord-022526-j9kg00qf 2784 23 swelling swelling NN cord-022526-j9kg00qf 2784 24 of of IN cord-022526-j9kg00qf 2784 25 the the DT cord-022526-j9kg00qf 2784 26 cervical cervical JJ cord-022526-j9kg00qf 2784 27 esophagus esophagus NN cord-022526-j9kg00qf 2784 28 as as IN cord-022526-j9kg00qf 2784 29 the the DT cord-022526-j9kg00qf 2784 30 cysts cyst NNS cord-022526-j9kg00qf 2784 31 enlarge enlarge VBP cord-022526-j9kg00qf 2784 32 . . . cord-022526-j9kg00qf 2785 1 47 47 CD cord-022526-j9kg00qf 2785 2 , , , cord-022526-j9kg00qf 2785 3 49 49 CD cord-022526-j9kg00qf 2785 4 , , , cord-022526-j9kg00qf 2785 5 50 50 CD cord-022526-j9kg00qf 2785 6 Such such JJ cord-022526-j9kg00qf 2785 7 signs sign NNS cord-022526-j9kg00qf 2785 8 can can MD cord-022526-j9kg00qf 2785 9 make make VB cord-022526-j9kg00qf 2785 10 them -PRON- PRP cord-022526-j9kg00qf 2785 11 difficult difficult JJ cord-022526-j9kg00qf 2785 12 to to TO cord-022526-j9kg00qf 2785 13 differentiate differentiate VB cord-022526-j9kg00qf 2785 14 from from IN cord-022526-j9kg00qf 2785 15 other other JJ cord-022526-j9kg00qf 2785 16 forms form NNS cord-022526-j9kg00qf 2785 17 of of IN cord-022526-j9kg00qf 2785 18 esophageal esophageal JJ cord-022526-j9kg00qf 2785 19 obstruction obstruction NN cord-022526-j9kg00qf 2785 20 ( ( -LRB- cord-022526-j9kg00qf 2785 21 choke choke VB cord-022526-j9kg00qf 2785 22 ) ) -RRB- cord-022526-j9kg00qf 2785 23 . . . cord-022526-j9kg00qf 2786 1 Endoscopic endoscopic JJ cord-022526-j9kg00qf 2786 2 examination examination NN cord-022526-j9kg00qf 2786 3 may may MD cord-022526-j9kg00qf 2786 4 reveal reveal VB cord-022526-j9kg00qf 2786 5 compression compression NN cord-022526-j9kg00qf 2786 6 of of IN cord-022526-j9kg00qf 2786 7 the the DT cord-022526-j9kg00qf 2786 8 esophageal esophageal JJ cord-022526-j9kg00qf 2786 9 lumen lumen NN cord-022526-j9kg00qf 2786 10 and and CC cord-022526-j9kg00qf 2786 11 communication communication NN cord-022526-j9kg00qf 2786 12 with with IN cord-022526-j9kg00qf 2786 13 the the DT cord-022526-j9kg00qf 2786 14 esophageal esophageal JJ cord-022526-j9kg00qf 2786 15 lumen lumen NN cord-022526-j9kg00qf 2786 16 if if IN cord-022526-j9kg00qf 2786 17 it -PRON- PRP cord-022526-j9kg00qf 2786 18 exists exist VBZ cord-022526-j9kg00qf 2786 19 . . . cord-022526-j9kg00qf 2787 1 Ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 2787 2 examination examination NN cord-022526-j9kg00qf 2787 3 may may MD cord-022526-j9kg00qf 2787 4 be be VB cord-022526-j9kg00qf 2787 5 the the DT cord-022526-j9kg00qf 2787 6 most most RBS cord-022526-j9kg00qf 2787 7 useful useful JJ cord-022526-j9kg00qf 2787 8 method method NN cord-022526-j9kg00qf 2787 9 of of IN cord-022526-j9kg00qf 2787 10 antemortem antemortem NNP cord-022526-j9kg00qf 2787 11 diagnosis diagnosis NN cord-022526-j9kg00qf 2787 12 if if IN cord-022526-j9kg00qf 2787 13 the the DT cord-022526-j9kg00qf 2787 14 cyst cyst NN cord-022526-j9kg00qf 2787 15 is be VBZ cord-022526-j9kg00qf 2787 16 in in IN cord-022526-j9kg00qf 2787 17 the the DT cord-022526-j9kg00qf 2787 18 cervical cervical JJ cord-022526-j9kg00qf 2787 19 esophagus esophagus NN cord-022526-j9kg00qf 2787 20 . . . cord-022526-j9kg00qf 2788 1 Examination examination NN cord-022526-j9kg00qf 2788 2 of of IN cord-022526-j9kg00qf 2788 3 an an DT cord-022526-j9kg00qf 2788 4 aspirate aspirate NN cord-022526-j9kg00qf 2788 5 of of IN cord-022526-j9kg00qf 2788 6 the the DT cord-022526-j9kg00qf 2788 7 mass mass NN cord-022526-j9kg00qf 2788 8 may may MD cord-022526-j9kg00qf 2788 9 aid aid VB cord-022526-j9kg00qf 2788 10 in in IN cord-022526-j9kg00qf 2788 11 the the DT cord-022526-j9kg00qf 2788 12 diagnosis diagnosis NN cord-022526-j9kg00qf 2788 13 by by IN cord-022526-j9kg00qf 2788 14 revealing reveal VBG cord-022526-j9kg00qf 2788 15 the the DT cord-022526-j9kg00qf 2788 16 presence presence NN cord-022526-j9kg00qf 2788 17 of of IN cord-022526-j9kg00qf 2788 18 keratinized keratinized JJ cord-022526-j9kg00qf 2788 19 squamous squamous JJ cord-022526-j9kg00qf 2788 20 cells cell NNS cord-022526-j9kg00qf 2788 21 . . . cord-022526-j9kg00qf 2789 1 47 47 CD cord-022526-j9kg00qf 2789 2 , , , cord-022526-j9kg00qf 2789 3 50 50 CD cord-022526-j9kg00qf 2789 4 Surgical surgical JJ cord-022526-j9kg00qf 2789 5 treatments treatment NNS cord-022526-j9kg00qf 2789 6 have have VBP cord-022526-j9kg00qf 2789 7 included include VBN cord-022526-j9kg00qf 2789 8 complete complete JJ cord-022526-j9kg00qf 2789 9 surgical surgical JJ cord-022526-j9kg00qf 2789 10 resection resection NN cord-022526-j9kg00qf 2789 11 and and CC cord-022526-j9kg00qf 2789 12 surgical surgical JJ cord-022526-j9kg00qf 2789 13 marsupialization marsupialization NN cord-022526-j9kg00qf 2789 14 . . . cord-022526-j9kg00qf 2790 1 47 47 CD cord-022526-j9kg00qf 2790 2 , , , cord-022526-j9kg00qf 2790 3 49 49 CD cord-022526-j9kg00qf 2790 4 , , , cord-022526-j9kg00qf 2790 5 50 50 CD cord-022526-j9kg00qf 2791 1 The the DT cord-022526-j9kg00qf 2791 2 latter latter NN cord-022526-j9kg00qf 2791 3 appears appear VBZ cord-022526-j9kg00qf 2791 4 to to TO cord-022526-j9kg00qf 2791 5 be be VB cord-022526-j9kg00qf 2791 6 more more RBR cord-022526-j9kg00qf 2791 7 successful successful JJ cord-022526-j9kg00qf 2791 8 and and CC cord-022526-j9kg00qf 2791 9 results result VBZ cord-022526-j9kg00qf 2791 10 in in IN cord-022526-j9kg00qf 2791 11 fewer few JJR cord-022526-j9kg00qf 2791 12 complications complication NNS cord-022526-j9kg00qf 2791 13 . . . cord-022526-j9kg00qf 2792 1 49 49 CD cord-022526-j9kg00qf 2792 2 , , , cord-022526-j9kg00qf 2792 3 50 50 CD cord-022526-j9kg00qf 2792 4 Complications complication NNS cord-022526-j9kg00qf 2792 5 of of IN cord-022526-j9kg00qf 2792 6 surgical surgical JJ cord-022526-j9kg00qf 2792 7 resection resection NN cord-022526-j9kg00qf 2792 8 have have VBP cord-022526-j9kg00qf 2792 9 included include VBN cord-022526-j9kg00qf 2792 10 laryngeal laryngeal NN cord-022526-j9kg00qf 2792 11 hemiplegia hemiplegia NN cord-022526-j9kg00qf 2792 12 following follow VBG cord-022526-j9kg00qf 2792 13 surgical surgical JJ cord-022526-j9kg00qf 2792 14 trauma trauma NN cord-022526-j9kg00qf 2792 15 to to IN cord-022526-j9kg00qf 2792 16 the the DT cord-022526-j9kg00qf 2792 17 recurrent recurrent JJ cord-022526-j9kg00qf 2792 18 laryngeal laryngeal NN cord-022526-j9kg00qf 2792 19 nerve nerve NN cord-022526-j9kg00qf 2792 20 in in IN cord-022526-j9kg00qf 2792 21 the the DT cord-022526-j9kg00qf 2792 22 region region NN cord-022526-j9kg00qf 2792 23 of of IN cord-022526-j9kg00qf 2792 24 the the DT cord-022526-j9kg00qf 2792 25 esophagus esophagus NN cord-022526-j9kg00qf 2792 26 and and CC cord-022526-j9kg00qf 2792 27 esophageal esophageal JJ cord-022526-j9kg00qf 2792 28 fistula fistula NN cord-022526-j9kg00qf 2792 29 formation formation NN cord-022526-j9kg00qf 2792 30 . . . cord-022526-j9kg00qf 2793 1 50 50 CD cord-022526-j9kg00qf 2793 2 Perforation perforation NN cord-022526-j9kg00qf 2793 3 typically typically RB cord-022526-j9kg00qf 2793 4 occurs occur VBZ cord-022526-j9kg00qf 2793 5 in in IN cord-022526-j9kg00qf 2793 6 the the DT cord-022526-j9kg00qf 2793 7 cervical cervical JJ cord-022526-j9kg00qf 2793 8 region region NN cord-022526-j9kg00qf 2793 9 in in IN cord-022526-j9kg00qf 2793 10 response response NN cord-022526-j9kg00qf 2793 11 to to IN cord-022526-j9kg00qf 2793 12 external external JJ cord-022526-j9kg00qf 2793 13 trauma trauma NN cord-022526-j9kg00qf 2793 14 , , , cord-022526-j9kg00qf 2793 15 necrosis necrosis NN cord-022526-j9kg00qf 2793 16 of of IN cord-022526-j9kg00qf 2793 17 the the DT cord-022526-j9kg00qf 2793 18 esophageal esophageal JJ cord-022526-j9kg00qf 2793 19 wall wall NN cord-022526-j9kg00qf 2793 20 caused cause VBN cord-022526-j9kg00qf 2793 21 by by IN cord-022526-j9kg00qf 2793 22 a a DT cord-022526-j9kg00qf 2793 23 food food NN cord-022526-j9kg00qf 2793 24 impaction impaction NN cord-022526-j9kg00qf 2793 25 , , , cord-022526-j9kg00qf 2793 26 or or CC cord-022526-j9kg00qf 2793 27 rupture rupture NN cord-022526-j9kg00qf 2793 28 of of IN cord-022526-j9kg00qf 2793 29 an an DT cord-022526-j9kg00qf 2793 30 esophageal esophageal JJ cord-022526-j9kg00qf 2793 31 lesion lesion NN cord-022526-j9kg00qf 2793 32 such such JJ cord-022526-j9kg00qf 2793 33 as as IN cord-022526-j9kg00qf 2793 34 an an DT cord-022526-j9kg00qf 2793 35 impacted impact VBN cord-022526-j9kg00qf 2793 36 diverticulum diverticulum NN cord-022526-j9kg00qf 2793 37 . . . cord-022526-j9kg00qf 2794 1 The the DT cord-022526-j9kg00qf 2794 2 esophagus esophagus NN cord-022526-j9kg00qf 2794 3 is be VBZ cord-022526-j9kg00qf 2794 4 particularly particularly RB cord-022526-j9kg00qf 2794 5 vulnerable vulnerable JJ cord-022526-j9kg00qf 2794 6 to to IN cord-022526-j9kg00qf 2794 7 external external JJ cord-022526-j9kg00qf 2794 8 trauma trauma NN cord-022526-j9kg00qf 2794 9 in in IN cord-022526-j9kg00qf 2794 10 the the DT cord-022526-j9kg00qf 2794 11 distal distal JJ cord-022526-j9kg00qf 2794 12 third third NN cord-022526-j9kg00qf 2794 13 of of IN cord-022526-j9kg00qf 2794 14 the the DT cord-022526-j9kg00qf 2794 15 neck neck NN cord-022526-j9kg00qf 2794 16 because because IN cord-022526-j9kg00qf 2794 17 only only RB cord-022526-j9kg00qf 2794 18 a a DT cord-022526-j9kg00qf 2794 19 thin thin JJ cord-022526-j9kg00qf 2794 20 layer layer NN cord-022526-j9kg00qf 2794 21 of of IN cord-022526-j9kg00qf 2794 22 muscle muscle NN cord-022526-j9kg00qf 2794 23 covers cover VBZ cord-022526-j9kg00qf 2794 24 it -PRON- PRP cord-022526-j9kg00qf 2794 25 at at IN cord-022526-j9kg00qf 2794 26 this this DT cord-022526-j9kg00qf 2794 27 point point NN cord-022526-j9kg00qf 2794 28 . . . cord-022526-j9kg00qf 2795 1 52 52 CD cord-022526-j9kg00qf 2795 2 Iatrogenic iatrogenic JJ cord-022526-j9kg00qf 2795 3 perforation perforation NN cord-022526-j9kg00qf 2795 4 may may MD cord-022526-j9kg00qf 2795 5 occur occur VB cord-022526-j9kg00qf 2795 6 in in IN cord-022526-j9kg00qf 2795 7 response response NN cord-022526-j9kg00qf 2795 8 to to IN cord-022526-j9kg00qf 2795 9 excessive excessive JJ cord-022526-j9kg00qf 2795 10 force force NN cord-022526-j9kg00qf 2795 11 with with IN cord-022526-j9kg00qf 2795 12 a a DT cord-022526-j9kg00qf 2795 13 stomach stomach NN cord-022526-j9kg00qf 2795 14 tube tube NN cord-022526-j9kg00qf 2795 15 against against IN cord-022526-j9kg00qf 2795 16 an an DT cord-022526-j9kg00qf 2795 17 obstruction obstruction NN cord-022526-j9kg00qf 2795 18 or or CC cord-022526-j9kg00qf 2795 19 a a DT cord-022526-j9kg00qf 2795 20 compromised compromised JJ cord-022526-j9kg00qf 2795 21 region region NN cord-022526-j9kg00qf 2795 22 of of IN cord-022526-j9kg00qf 2795 23 the the DT cord-022526-j9kg00qf 2795 24 esophagus esophagus NN cord-022526-j9kg00qf 2795 25 . . . cord-022526-j9kg00qf 2796 1 24 24 CD cord-022526-j9kg00qf 2796 2 Esophageal esophageal JJ cord-022526-j9kg00qf 2796 3 perforations perforation NNS cord-022526-j9kg00qf 2796 4 may may MD cord-022526-j9kg00qf 2796 5 be be VB cord-022526-j9kg00qf 2796 6 open open JJ cord-022526-j9kg00qf 2796 7 or or CC cord-022526-j9kg00qf 2796 8 closed closed JJ cord-022526-j9kg00qf 2796 9 and and CC cord-022526-j9kg00qf 2796 10 tend tend VB cord-022526-j9kg00qf 2796 11 to to TO cord-022526-j9kg00qf 2796 12 cause cause VB cord-022526-j9kg00qf 2796 13 extensive extensive JJ cord-022526-j9kg00qf 2796 14 cellulitis cellulitis NN cord-022526-j9kg00qf 2796 15 and and CC cord-022526-j9kg00qf 2796 16 necrosis necrosis NN cord-022526-j9kg00qf 2796 17 of of IN cord-022526-j9kg00qf 2796 18 tissues tissue NNS cord-022526-j9kg00qf 2796 19 surrounding surround VBG cord-022526-j9kg00qf 2796 20 the the DT cord-022526-j9kg00qf 2796 21 wound wound NN cord-022526-j9kg00qf 2796 22 because because IN cord-022526-j9kg00qf 2796 23 of of IN cord-022526-j9kg00qf 2796 24 drainage drainage NN cord-022526-j9kg00qf 2796 25 of of IN cord-022526-j9kg00qf 2796 26 saliva saliva NN cord-022526-j9kg00qf 2796 27 and and CC cord-022526-j9kg00qf 2796 28 feed feed VB cord-022526-j9kg00qf 2796 29 material material NN cord-022526-j9kg00qf 2796 30 within within IN cord-022526-j9kg00qf 2796 31 fascial fascial JJ cord-022526-j9kg00qf 2796 32 planes plane NNS cord-022526-j9kg00qf 2796 33 . . . cord-022526-j9kg00qf 2797 1 Systemic systemic JJ cord-022526-j9kg00qf 2797 2 inflammation inflammation NN cord-022526-j9kg00qf 2797 3 associated associate VBN cord-022526-j9kg00qf 2797 4 with with IN cord-022526-j9kg00qf 2797 5 endotoxemia endotoxemia NN cord-022526-j9kg00qf 2797 6 from from IN cord-022526-j9kg00qf 2797 7 septic septic JJ cord-022526-j9kg00qf 2797 8 cellulitis cellulitis NN cord-022526-j9kg00qf 2797 9 may may MD cord-022526-j9kg00qf 2797 10 occur occur VB cord-022526-j9kg00qf 2797 11 . . . cord-022526-j9kg00qf 2798 1 Closed closed JJ cord-022526-j9kg00qf 2798 2 perforations perforation NNS cord-022526-j9kg00qf 2798 3 of of IN cord-022526-j9kg00qf 2798 4 the the DT cord-022526-j9kg00qf 2798 5 esophagus esophagus NN cord-022526-j9kg00qf 2798 6 are be VBP cord-022526-j9kg00qf 2798 7 particularly particularly RB cord-022526-j9kg00qf 2798 8 troublesome troublesome JJ cord-022526-j9kg00qf 2798 9 because because IN cord-022526-j9kg00qf 2798 10 food food NN cord-022526-j9kg00qf 2798 11 material material NN cord-022526-j9kg00qf 2798 12 , , , cord-022526-j9kg00qf 2798 13 water water NN cord-022526-j9kg00qf 2798 14 , , , cord-022526-j9kg00qf 2798 15 saliva saliva NN cord-022526-j9kg00qf 2798 16 , , , cord-022526-j9kg00qf 2798 17 and and CC cord-022526-j9kg00qf 2798 18 air air NN cord-022526-j9kg00qf 2798 19 may may MD cord-022526-j9kg00qf 2798 20 migrate migrate VB cord-022526-j9kg00qf 2798 21 to to IN cord-022526-j9kg00qf 2798 22 the the DT cord-022526-j9kg00qf 2798 23 mediastinum mediastinum NN cord-022526-j9kg00qf 2798 24 and and CC cord-022526-j9kg00qf 2798 25 pleural pleural JJ cord-022526-j9kg00qf 2798 26 space space NN cord-022526-j9kg00qf 2798 27 via via IN cord-022526-j9kg00qf 2798 28 fascial fascial JJ cord-022526-j9kg00qf 2798 29 planes plane NNS cord-022526-j9kg00qf 2798 30 . . . cord-022526-j9kg00qf 2799 1 24 24 CD cord-022526-j9kg00qf 2799 2 , , , cord-022526-j9kg00qf 2799 3 52 52 CD cord-022526-j9kg00qf 2799 4 Because because IN cord-022526-j9kg00qf 2799 5 of of IN cord-022526-j9kg00qf 2799 6 the the DT cord-022526-j9kg00qf 2799 7 leakage leakage NN cord-022526-j9kg00qf 2799 8 of of IN cord-022526-j9kg00qf 2799 9 air air NN cord-022526-j9kg00qf 2799 10 into into IN cord-022526-j9kg00qf 2799 11 the the DT cord-022526-j9kg00qf 2799 12 tissues tissue NNS cord-022526-j9kg00qf 2799 13 surrounding surround VBG cord-022526-j9kg00qf 2799 14 the the DT cord-022526-j9kg00qf 2799 15 rupture rupture NN cord-022526-j9kg00qf 2799 16 , , , cord-022526-j9kg00qf 2799 17 extensive extensive JJ cord-022526-j9kg00qf 2799 18 subcutaneous subcutaneous JJ cord-022526-j9kg00qf 2799 19 and and CC cord-022526-j9kg00qf 2799 20 fascial fascial JJ cord-022526-j9kg00qf 2799 21 emphysema emphysema NN cord-022526-j9kg00qf 2799 22 frequently frequently RB cord-022526-j9kg00qf 2799 23 develops develop VBZ cord-022526-j9kg00qf 2799 24 and and CC cord-022526-j9kg00qf 2799 25 is be VBZ cord-022526-j9kg00qf 2799 26 usually usually RB cord-022526-j9kg00qf 2799 27 evident evident JJ cord-022526-j9kg00qf 2799 28 clinically clinically RB cord-022526-j9kg00qf 2799 29 and and CC cord-022526-j9kg00qf 2799 30 on on IN cord-022526-j9kg00qf 2799 31 cervical cervical JJ cord-022526-j9kg00qf 2799 32 radiographs radiograph NNS cord-022526-j9kg00qf 2799 33 . . . cord-022526-j9kg00qf 2800 1 Pneumomediastinum Pneumomediastinum NNP cord-022526-j9kg00qf 2800 2 and and CC cord-022526-j9kg00qf 2800 3 pneumothorax pneumothorax NN cord-022526-j9kg00qf 2800 4 are be VBP cord-022526-j9kg00qf 2800 5 potentially potentially RB cord-022526-j9kg00qf 2800 6 fatal fatal JJ cord-022526-j9kg00qf 2800 7 complications complication NNS cord-022526-j9kg00qf 2800 8 of of IN cord-022526-j9kg00qf 2800 9 esophageal esophageal JJ cord-022526-j9kg00qf 2800 10 ruptures rupture NNS cord-022526-j9kg00qf 2800 11 . . . cord-022526-j9kg00qf 2801 1 Treatment treatment NN cord-022526-j9kg00qf 2801 2 should should MD cord-022526-j9kg00qf 2801 3 include include VB cord-022526-j9kg00qf 2801 4 converting convert VBG cord-022526-j9kg00qf 2801 5 closed closed JJ cord-022526-j9kg00qf 2801 6 perforations perforation NNS cord-022526-j9kg00qf 2801 7 to to TO cord-022526-j9kg00qf 2801 8 open open VB cord-022526-j9kg00qf 2801 9 perforations perforation NNS cord-022526-j9kg00qf 2801 10 if if IN cord-022526-j9kg00qf 2801 11 possible possible JJ cord-022526-j9kg00qf 2801 12 , , , cord-022526-j9kg00qf 2801 13 53 53 CD cord-022526-j9kg00qf 2801 14 extensive extensive JJ cord-022526-j9kg00qf 2801 15 debridement debridement NN cord-022526-j9kg00qf 2801 16 and and CC cord-022526-j9kg00qf 2801 17 lavage lavage NN cord-022526-j9kg00qf 2801 18 of of IN cord-022526-j9kg00qf 2801 19 affected affected JJ cord-022526-j9kg00qf 2801 20 tissues tissue NNS cord-022526-j9kg00qf 2801 21 , , , cord-022526-j9kg00qf 2801 22 broadspectrum broadspectrum NNP cord-022526-j9kg00qf 2801 23 antibiotics antibiotic NNS cord-022526-j9kg00qf 2801 24 , , , cord-022526-j9kg00qf 2801 25 tetanus tetanus NN cord-022526-j9kg00qf 2801 26 prophylaxis prophylaxis NN cord-022526-j9kg00qf 2801 27 , , , cord-022526-j9kg00qf 2801 28 and and CC cord-022526-j9kg00qf 2801 29 esophageal esophageal JJ cord-022526-j9kg00qf 2801 30 rest rest NN cord-022526-j9kg00qf 2801 31 . . . cord-022526-j9kg00qf 2802 1 The the DT cord-022526-j9kg00qf 2802 2 clinician clinician NN cord-022526-j9kg00qf 2802 3 may may MD cord-022526-j9kg00qf 2802 4 achieve achieve VB cord-022526-j9kg00qf 2802 5 the the DT cord-022526-j9kg00qf 2802 6 latter latter JJ cord-022526-j9kg00qf 2802 7 by by IN cord-022526-j9kg00qf 2802 8 placing place VBG cord-022526-j9kg00qf 2802 9 a a DT cord-022526-j9kg00qf 2802 10 feeding feeding NN cord-022526-j9kg00qf 2802 11 tube tube NN cord-022526-j9kg00qf 2802 12 into into IN cord-022526-j9kg00qf 2802 13 the the DT cord-022526-j9kg00qf 2802 14 esophagus esophagus NN cord-022526-j9kg00qf 2802 15 via via IN cord-022526-j9kg00qf 2802 16 the the DT cord-022526-j9kg00qf 2802 17 wound wound NN cord-022526-j9kg00qf 2802 18 . . . cord-022526-j9kg00qf 2803 1 Alternatively alternatively RB cord-022526-j9kg00qf 2803 2 , , , cord-022526-j9kg00qf 2803 3 one one PRP cord-022526-j9kg00qf 2803 4 may may MD cord-022526-j9kg00qf 2803 5 place place VB cord-022526-j9kg00qf 2803 6 a a DT cord-022526-j9kg00qf 2803 7 nasogastric nasogastric NN cord-022526-j9kg00qf 2803 8 tube tube NN cord-022526-j9kg00qf 2803 9 using use VBG cord-022526-j9kg00qf 2803 10 a a DT cord-022526-j9kg00qf 2803 11 small small JJ cord-022526-j9kg00qf 2803 12 tube tube NN cord-022526-j9kg00qf 2803 13 ( ( -LRB- cord-022526-j9kg00qf 2803 14 12-F 12-f NN cord-022526-j9kg00qf 2803 15 diameter diameter NN cord-022526-j9kg00qf 2803 16 ) ) -RRB- cord-022526-j9kg00qf 2803 17 . . . cord-022526-j9kg00qf 2804 1 24 24 CD cord-022526-j9kg00qf 2805 1 For for IN cord-022526-j9kg00qf 2805 2 open open JJ cord-022526-j9kg00qf 2805 3 perforations perforation NNS cord-022526-j9kg00qf 2805 4 , , , cord-022526-j9kg00qf 2805 5 once once IN cord-022526-j9kg00qf 2805 6 the the DT cord-022526-j9kg00qf 2805 7 wound wound NN cord-022526-j9kg00qf 2805 8 has have VBZ cord-022526-j9kg00qf 2805 9 granulated granulate VBN cord-022526-j9kg00qf 2805 10 and and CC cord-022526-j9kg00qf 2805 11 contracted contract VBN cord-022526-j9kg00qf 2805 12 to to IN cord-022526-j9kg00qf 2805 13 a a DT cord-022526-j9kg00qf 2805 14 small small JJ cord-022526-j9kg00qf 2805 15 size size NN cord-022526-j9kg00qf 2805 16 , , , cord-022526-j9kg00qf 2805 17 one one PRP cord-022526-j9kg00qf 2805 18 may may MD cord-022526-j9kg00qf 2805 19 attempt attempt VB cord-022526-j9kg00qf 2805 20 peroral peroral JJ cord-022526-j9kg00qf 2805 21 feeding feeding NN cord-022526-j9kg00qf 2805 22 . . . cord-022526-j9kg00qf 2806 1 52 52 CD cord-022526-j9kg00qf 2806 2 Extensive extensive JJ cord-022526-j9kg00qf 2806 3 loss loss NN cord-022526-j9kg00qf 2806 4 of of IN cord-022526-j9kg00qf 2806 5 saliva saliva NN cord-022526-j9kg00qf 2806 6 via via IN cord-022526-j9kg00qf 2806 7 esophageal esophageal JJ cord-022526-j9kg00qf 2806 8 wounds wound NNS cord-022526-j9kg00qf 2806 9 may may MD cord-022526-j9kg00qf 2806 10 lead lead VB cord-022526-j9kg00qf 2806 11 to to IN cord-022526-j9kg00qf 2806 12 hyponatremia hyponatremia NN cord-022526-j9kg00qf 2806 13 and and CC cord-022526-j9kg00qf 2806 14 hypochloremia hypochloremia NN cord-022526-j9kg00qf 2806 15 . . . cord-022526-j9kg00qf 2807 1 In in IN cord-022526-j9kg00qf 2807 2 addition addition NN cord-022526-j9kg00qf 2807 3 , , , cord-022526-j9kg00qf 2807 4 transient transient JJ cord-022526-j9kg00qf 2807 5 metabolic metabolic JJ cord-022526-j9kg00qf 2807 6 acidosis acidosis NN cord-022526-j9kg00qf 2807 7 occurs occur VBZ cord-022526-j9kg00qf 2807 8 because because IN cord-022526-j9kg00qf 2807 9 of of IN cord-022526-j9kg00qf 2807 10 salivary salivary JJ cord-022526-j9kg00qf 2807 11 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2807 12 loss loss NN cord-022526-j9kg00qf 2807 13 , , , cord-022526-j9kg00qf 2807 14 followed follow VBN cord-022526-j9kg00qf 2807 15 by by IN cord-022526-j9kg00qf 2807 16 progressive progressive JJ cord-022526-j9kg00qf 2807 17 metabolic metabolic JJ cord-022526-j9kg00qf 2807 18 alkalosis alkalosis NN cord-022526-j9kg00qf 2807 19 . . . cord-022526-j9kg00qf 2808 1 21 21 CD cord-022526-j9kg00qf 2809 1 Although although IN cord-022526-j9kg00qf 2809 2 reports report NNS cord-022526-j9kg00qf 2809 3 of of IN cord-022526-j9kg00qf 2809 4 esophageal esophageal JJ cord-022526-j9kg00qf 2809 5 wounds wound NNS cord-022526-j9kg00qf 2809 6 healing heal VBG cord-022526-j9kg00qf 2809 7 well well RB cord-022526-j9kg00qf 2809 8 by by IN cord-022526-j9kg00qf 2809 9 second second JJ cord-022526-j9kg00qf 2809 10 intention intention NN cord-022526-j9kg00qf 2809 11 exist exist VB cord-022526-j9kg00qf 2809 12 , , , cord-022526-j9kg00qf 2809 13 healing healing NN cord-022526-j9kg00qf 2809 14 takes take VBZ cord-022526-j9kg00qf 2809 15 a a DT cord-022526-j9kg00qf 2809 16 prolonged prolonged JJ cord-022526-j9kg00qf 2809 17 time time NN cord-022526-j9kg00qf 2809 18 . . . cord-022526-j9kg00qf 2810 1 54 54 CD cord-022526-j9kg00qf 2811 1 In in IN cord-022526-j9kg00qf 2811 2 addition addition NN cord-022526-j9kg00qf 2811 3 , , , cord-022526-j9kg00qf 2811 4 some some DT cord-022526-j9kg00qf 2811 5 perforations perforation NNS cord-022526-j9kg00qf 2811 6 never never RB cord-022526-j9kg00qf 2811 7 completely completely RB cord-022526-j9kg00qf 2811 8 heal heal VB cord-022526-j9kg00qf 2811 9 and and CC cord-022526-j9kg00qf 2811 10 form form VB cord-022526-j9kg00qf 2811 11 permanent permanent JJ cord-022526-j9kg00qf 2811 12 esophagocutaneous esophagocutaneous JJ cord-022526-j9kg00qf 2811 13 fistulae fistula NNS cord-022526-j9kg00qf 2811 14 that that WDT cord-022526-j9kg00qf 2811 15 may may MD cord-022526-j9kg00qf 2811 16 require require VB cord-022526-j9kg00qf 2811 17 surgical surgical JJ cord-022526-j9kg00qf 2811 18 correction correction NN cord-022526-j9kg00qf 2811 19 . . . cord-022526-j9kg00qf 2812 1 The the DT cord-022526-j9kg00qf 2812 2 development development NN cord-022526-j9kg00qf 2812 3 of of IN cord-022526-j9kg00qf 2812 4 esophageal esophageal JJ cord-022526-j9kg00qf 2812 5 strictures stricture NNS cord-022526-j9kg00qf 2812 6 is be VBZ cord-022526-j9kg00qf 2812 7 not not RB cord-022526-j9kg00qf 2812 8 common common JJ cord-022526-j9kg00qf 2812 9 because because IN cord-022526-j9kg00qf 2812 10 wounds wound NNS cord-022526-j9kg00qf 2812 11 are be VBP cord-022526-j9kg00qf 2812 12 usually usually RB cord-022526-j9kg00qf 2812 13 linear linear JJ cord-022526-j9kg00qf 2812 14 and and CC cord-022526-j9kg00qf 2812 15 not not RB cord-022526-j9kg00qf 2812 16 circumferential circumferential JJ cord-022526-j9kg00qf 2812 17 . . . cord-022526-j9kg00qf 2813 1 However however RB cord-022526-j9kg00qf 2813 2 , , , cord-022526-j9kg00qf 2813 3 traction traction NN cord-022526-j9kg00qf 2813 4 diverticula diverticula NN cord-022526-j9kg00qf 2813 5 may may MD cord-022526-j9kg00qf 2813 6 develop develop VB cord-022526-j9kg00qf 2813 7 . . . cord-022526-j9kg00qf 2814 1 Other other JJ cord-022526-j9kg00qf 2814 2 complications complication NNS cord-022526-j9kg00qf 2814 3 of of IN cord-022526-j9kg00qf 2814 4 esophageal esophageal JJ cord-022526-j9kg00qf 2814 5 wounds wound NNS cord-022526-j9kg00qf 2814 6 include include VBP cord-022526-j9kg00qf 2814 7 Horner Horner NNP cord-022526-j9kg00qf 2814 8 's 's POS cord-022526-j9kg00qf 2814 9 syndrome syndrome NN cord-022526-j9kg00qf 2814 10 and and CC cord-022526-j9kg00qf 2814 11 left left JJ cord-022526-j9kg00qf 2814 12 laryngeal laryngeal NN cord-022526-j9kg00qf 2814 13 hemiplegia hemiplegia NN cord-022526-j9kg00qf 2814 14 . . . cord-022526-j9kg00qf 2815 1 52 52 CD cord-022526-j9kg00qf 2816 1 In in IN cord-022526-j9kg00qf 2816 2 a a DT cord-022526-j9kg00qf 2816 3 retrospective retrospective JJ cord-022526-j9kg00qf 2816 4 study study NN cord-022526-j9kg00qf 2816 5 on on IN cord-022526-j9kg00qf 2816 6 esophageal esophageal JJ cord-022526-j9kg00qf 2816 7 disorders disorder NNS cord-022526-j9kg00qf 2816 8 , , , cord-022526-j9kg00qf 2816 9 only only RB cord-022526-j9kg00qf 2816 10 2 2 CD cord-022526-j9kg00qf 2816 11 of of IN cord-022526-j9kg00qf 2816 12 11 11 CD cord-022526-j9kg00qf 2816 13 horses horse NNS cord-022526-j9kg00qf 2816 14 with with IN cord-022526-j9kg00qf 2816 15 esophageal esophageal JJ cord-022526-j9kg00qf 2816 16 perforations perforation NNS cord-022526-j9kg00qf 2816 17 survived survive VBD cord-022526-j9kg00qf 2816 18 long long JJ cord-022526-j9kg00qf 2816 19 - - HYPH cord-022526-j9kg00qf 2816 20 term term NN cord-022526-j9kg00qf 2816 21 3 3 CD cord-022526-j9kg00qf 2816 22 ; ; : cord-022526-j9kg00qf 2816 23 in in IN cord-022526-j9kg00qf 2816 24 a a DT cord-022526-j9kg00qf 2816 25 report report NN cord-022526-j9kg00qf 2816 26 of of IN cord-022526-j9kg00qf 2816 27 esophageal esophageal JJ cord-022526-j9kg00qf 2816 28 trauma trauma NN cord-022526-j9kg00qf 2816 29 following follow VBG cord-022526-j9kg00qf 2816 30 nasogastric nasogastric NN cord-022526-j9kg00qf 2816 31 intubation intubation NN cord-022526-j9kg00qf 2816 32 , , , cord-022526-j9kg00qf 2816 33 4 4 CD cord-022526-j9kg00qf 2816 34 of of IN cord-022526-j9kg00qf 2816 35 5 5 CD cord-022526-j9kg00qf 2816 36 horses horse NNS cord-022526-j9kg00qf 2816 37 were be VBD cord-022526-j9kg00qf 2816 38 euthanized euthanize VBN cord-022526-j9kg00qf 2816 39 . . . cord-022526-j9kg00qf 2817 1 24 24 CD cord-022526-j9kg00qf 2818 1 The the DT cord-022526-j9kg00qf 2818 2 prognosis prognosis NN cord-022526-j9kg00qf 2818 3 is be VBZ cord-022526-j9kg00qf 2818 4 therefore therefore RB cord-022526-j9kg00qf 2818 5 poor poor JJ cord-022526-j9kg00qf 2818 6 in in IN cord-022526-j9kg00qf 2818 7 horses horse NNS cord-022526-j9kg00qf 2818 8 with with IN cord-022526-j9kg00qf 2818 9 esophageal esophageal JJ cord-022526-j9kg00qf 2818 10 perforations perforation NNS cord-022526-j9kg00qf 2818 11 , , , cord-022526-j9kg00qf 2818 12 largely largely RB cord-022526-j9kg00qf 2818 13 because because IN cord-022526-j9kg00qf 2818 14 of of IN cord-022526-j9kg00qf 2818 15 the the DT cord-022526-j9kg00qf 2818 16 extent extent NN cord-022526-j9kg00qf 2818 17 of of IN cord-022526-j9kg00qf 2818 18 cellulitis cellulitis NN cord-022526-j9kg00qf 2818 19 , , , cord-022526-j9kg00qf 2818 20 tissue tissue NN cord-022526-j9kg00qf 2818 21 necrosis necrosis NN cord-022526-j9kg00qf 2818 22 , , , cord-022526-j9kg00qf 2818 23 shock shock NN cord-022526-j9kg00qf 2818 24 , , , cord-022526-j9kg00qf 2818 25 and and CC cord-022526-j9kg00qf 2818 26 local local JJ cord-022526-j9kg00qf 2818 27 wound wound NN cord-022526-j9kg00qf 2818 28 complications complication NNS cord-022526-j9kg00qf 2818 29 . . . cord-022526-j9kg00qf 2819 1 14 14 CD cord-022526-j9kg00qf 2819 2 _SP cord-022526-j9kg00qf 2820 1 Specialized specialized JJ cord-022526-j9kg00qf 2820 2 endoscopic endoscopic NN cord-022526-j9kg00qf 2820 3 equipment equipment NN cord-022526-j9kg00qf 2820 4 allowing allow VBG cord-022526-j9kg00qf 2820 5 visual visual JJ cord-022526-j9kg00qf 2820 6 inspection inspection NN cord-022526-j9kg00qf 2820 7 of of IN cord-022526-j9kg00qf 2820 8 the the DT cord-022526-j9kg00qf 2820 9 entire entire JJ cord-022526-j9kg00qf 2820 10 adult adult NN cord-022526-j9kg00qf 2820 11 equine equine JJ cord-022526-j9kg00qf 2820 12 stomach stomach NN cord-022526-j9kg00qf 2820 13 has have VBZ cord-022526-j9kg00qf 2820 14 become become VBN cord-022526-j9kg00qf 2820 15 increasingly increasingly RB cord-022526-j9kg00qf 2820 16 available available JJ cord-022526-j9kg00qf 2820 17 to to IN cord-022526-j9kg00qf 2820 18 veterinarians veterinarian NNS cord-022526-j9kg00qf 2820 19 in in IN cord-022526-j9kg00qf 2820 20 academia academia NN cord-022526-j9kg00qf 2820 21 and and CC cord-022526-j9kg00qf 2820 22 private private JJ cord-022526-j9kg00qf 2820 23 practice practice NN cord-022526-j9kg00qf 2820 24 . . . cord-022526-j9kg00qf 2821 1 Thus thus RB cord-022526-j9kg00qf 2821 2 gastric gastric JJ cord-022526-j9kg00qf 2821 3 disease disease NN cord-022526-j9kg00qf 2821 4 in in IN cord-022526-j9kg00qf 2821 5 horses horse NNS cord-022526-j9kg00qf 2821 6 recently recently RB cord-022526-j9kg00qf 2821 7 SECTION SECTION VBZ cord-022526-j9kg00qf 2821 8 13 13 CD cord-022526-j9kg00qf 2821 9 .10 .10 . cord-022526-j9kg00qf 2822 1 Diseases disease NNS cord-022526-j9kg00qf 2822 2 of of IN cord-022526-j9kg00qf 2822 3 the the DT cord-022526-j9kg00qf 2822 4 Stomach stomach NN cord-022526-j9kg00qf 2822 5 has have VBZ cord-022526-j9kg00qf 2822 6 gained gain VBN cord-022526-j9kg00qf 2822 7 increasing increase VBG cord-022526-j9kg00qf 2822 8 awareness awareness NN cord-022526-j9kg00qf 2822 9 among among IN cord-022526-j9kg00qf 2822 10 veterinarians veterinarian NNS cord-022526-j9kg00qf 2822 11 , , , cord-022526-j9kg00qf 2822 12 owners owner NNS cord-022526-j9kg00qf 2822 13 , , , cord-022526-j9kg00qf 2822 14 and and CC cord-022526-j9kg00qf 2822 15 trainers trainer NNS cord-022526-j9kg00qf 2822 16 . . . cord-022526-j9kg00qf 2823 1 Peptic peptic JJ cord-022526-j9kg00qf 2823 2 ulcer ulcer NN cord-022526-j9kg00qf 2823 3 disease disease NN cord-022526-j9kg00qf 2823 4 is be VBZ cord-022526-j9kg00qf 2823 5 defined define VBN cord-022526-j9kg00qf 2823 6 as as IN cord-022526-j9kg00qf 2823 7 erosions erosion NNS cord-022526-j9kg00qf 2823 8 or or CC cord-022526-j9kg00qf 2823 9 ulcers ulcer NNS cord-022526-j9kg00qf 2823 10 of of IN cord-022526-j9kg00qf 2823 11 any any DT cord-022526-j9kg00qf 2823 12 portion portion NN cord-022526-j9kg00qf 2823 13 of of IN cord-022526-j9kg00qf 2823 14 the the DT cord-022526-j9kg00qf 2823 15 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2823 16 tract tract NN cord-022526-j9kg00qf 2823 17 normally normally RB cord-022526-j9kg00qf 2823 18 exposed expose VBN cord-022526-j9kg00qf 2823 19 to to IN cord-022526-j9kg00qf 2823 20 acid acid NN cord-022526-j9kg00qf 2823 21 . . . cord-022526-j9kg00qf 2824 1 1 1 LS cord-022526-j9kg00qf 2825 1 Mucosal Mucosal NNP cord-022526-j9kg00qf 2825 2 damage damage NN cord-022526-j9kg00qf 2825 3 can can MD cord-022526-j9kg00qf 2825 4 include include VB cord-022526-j9kg00qf 2825 5 inflammation inflammation NN cord-022526-j9kg00qf 2825 6 , , , cord-022526-j9kg00qf 2825 7 erosion erosion NN cord-022526-j9kg00qf 2825 8 ( ( -LRB- cord-022526-j9kg00qf 2825 9 disruption disruption NN cord-022526-j9kg00qf 2825 10 of of IN cord-022526-j9kg00qf 2825 11 the the DT cord-022526-j9kg00qf 2825 12 superficial superficial JJ cord-022526-j9kg00qf 2825 13 mucosa mucosa NN cord-022526-j9kg00qf 2825 14 ) ) -RRB- cord-022526-j9kg00qf 2825 15 , , , cord-022526-j9kg00qf 2825 16 or or CC cord-022526-j9kg00qf 2825 17 ulceration ulceration NN cord-022526-j9kg00qf 2825 18 ( ( -LRB- cord-022526-j9kg00qf 2825 19 penetration penetration NN cord-022526-j9kg00qf 2825 20 of of IN cord-022526-j9kg00qf 2825 21 the the DT cord-022526-j9kg00qf 2825 22 submucosa submucosa NNP cord-022526-j9kg00qf 2825 23 ) ) -RRB- cord-022526-j9kg00qf 2825 24 . . . cord-022526-j9kg00qf 2826 1 In in IN cord-022526-j9kg00qf 2826 2 severe severe JJ cord-022526-j9kg00qf 2826 3 cases case NNS cord-022526-j9kg00qf 2826 4 , , , cord-022526-j9kg00qf 2826 5 fullthickness fullthickness JJ cord-022526-j9kg00qf 2826 6 ulceration ulceration NN cord-022526-j9kg00qf 2826 7 can can MD cord-022526-j9kg00qf 2826 8 occur occur VB cord-022526-j9kg00qf 2826 9 , , , cord-022526-j9kg00qf 2826 10 resulting result VBG cord-022526-j9kg00qf 2826 11 in in IN cord-022526-j9kg00qf 2826 12 perforation perforation NN cord-022526-j9kg00qf 2826 13 . . . cord-022526-j9kg00qf 2827 1 The the DT cord-022526-j9kg00qf 2827 2 proximal proximal JJ cord-022526-j9kg00qf 2827 3 ( ( -LRB- cord-022526-j9kg00qf 2827 4 orad orad NNP cord-022526-j9kg00qf 2827 5 ) ) -RRB- cord-022526-j9kg00qf 2827 6 portion portion NN cord-022526-j9kg00qf 2827 7 of of IN cord-022526-j9kg00qf 2827 8 the the DT cord-022526-j9kg00qf 2827 9 equine equine JJ cord-022526-j9kg00qf 2827 10 stomach stomach NN cord-022526-j9kg00qf 2827 11 is be VBZ cord-022526-j9kg00qf 2827 12 lined line VBN cord-022526-j9kg00qf 2827 13 by by IN cord-022526-j9kg00qf 2827 14 stratified stratified JJ cord-022526-j9kg00qf 2827 15 squamous squamous JJ cord-022526-j9kg00qf 2827 16 mucosa mucosa NN cord-022526-j9kg00qf 2827 17 similar similar JJ cord-022526-j9kg00qf 2827 18 to to IN cord-022526-j9kg00qf 2827 19 the the DT cord-022526-j9kg00qf 2827 20 esophageal esophageal JJ cord-022526-j9kg00qf 2827 21 lining lining NN cord-022526-j9kg00qf 2827 22 . . . cord-022526-j9kg00qf 2828 1 The the DT cord-022526-j9kg00qf 2828 2 distal distal JJ cord-022526-j9kg00qf 2828 3 ( ( -LRB- cord-022526-j9kg00qf 2828 4 aborad aborad NNP cord-022526-j9kg00qf 2828 5 ) ) -RRB- cord-022526-j9kg00qf 2828 6 portion portion NN cord-022526-j9kg00qf 2828 7 of of IN cord-022526-j9kg00qf 2828 8 the the DT cord-022526-j9kg00qf 2828 9 stomach stomach NN cord-022526-j9kg00qf 2828 10 is be VBZ cord-022526-j9kg00qf 2828 11 lined line VBN cord-022526-j9kg00qf 2828 12 with with IN cord-022526-j9kg00qf 2828 13 glandular glandular JJ cord-022526-j9kg00qf 2828 14 mucosa mucosa NN cord-022526-j9kg00qf 2828 15 , , , cord-022526-j9kg00qf 2828 16 and and CC cord-022526-j9kg00qf 2828 17 the the DT cord-022526-j9kg00qf 2828 18 distinct distinct JJ cord-022526-j9kg00qf 2828 19 junction junction NN cord-022526-j9kg00qf 2828 20 between between IN cord-022526-j9kg00qf 2828 21 the the DT cord-022526-j9kg00qf 2828 22 two two CD cord-022526-j9kg00qf 2828 23 regions region NNS cord-022526-j9kg00qf 2828 24 is be VBZ cord-022526-j9kg00qf 2828 25 deemed deem VBN cord-022526-j9kg00qf 2828 26 the the DT cord-022526-j9kg00qf 2828 27 margo margo NNP cord-022526-j9kg00qf 2828 28 plicatus plicatus NNP cord-022526-j9kg00qf 2828 29 . . . cord-022526-j9kg00qf 2829 1 Ulceration ulceration NN cord-022526-j9kg00qf 2829 2 can can MD cord-022526-j9kg00qf 2829 3 occur occur VB cord-022526-j9kg00qf 2829 4 in in IN cord-022526-j9kg00qf 2829 5 either either DT cord-022526-j9kg00qf 2829 6 or or CC cord-022526-j9kg00qf 2829 7 both both CC cord-022526-j9kg00qf 2829 8 gastric gastric JJ cord-022526-j9kg00qf 2829 9 regions region NNS cord-022526-j9kg00qf 2829 10 , , , cord-022526-j9kg00qf 2829 11 although although IN cord-022526-j9kg00qf 2829 12 different different JJ cord-022526-j9kg00qf 2829 13 clinical clinical JJ cord-022526-j9kg00qf 2829 14 syndromes syndrome NNS cord-022526-j9kg00qf 2829 15 and and CC cord-022526-j9kg00qf 2829 16 pathophysiologic pathophysiologic NN cord-022526-j9kg00qf 2829 17 mechanisms mechanism NNS cord-022526-j9kg00qf 2829 18 apply apply VBP cord-022526-j9kg00qf 2829 19 . . . cord-022526-j9kg00qf 2830 1 As as IN cord-022526-j9kg00qf 2830 2 a a DT cord-022526-j9kg00qf 2830 3 result result NN cord-022526-j9kg00qf 2830 4 , , , cord-022526-j9kg00qf 2830 5 the the DT cord-022526-j9kg00qf 2830 6 broad broad JJ cord-022526-j9kg00qf 2830 7 term term NN cord-022526-j9kg00qf 2830 8 equine equine JJ cord-022526-j9kg00qf 2830 9 gastric gastric JJ cord-022526-j9kg00qf 2830 10 ulcer ulcer NN cord-022526-j9kg00qf 2830 11 syndrome syndrome NN cord-022526-j9kg00qf 2830 12 ( ( -LRB- cord-022526-j9kg00qf 2830 13 EGUS EGUS NNP cord-022526-j9kg00qf 2830 14 ) ) -RRB- cord-022526-j9kg00qf 2830 15 has have VBZ cord-022526-j9kg00qf 2830 16 been be VBN cord-022526-j9kg00qf 2830 17 used use VBN cord-022526-j9kg00qf 2830 18 to to TO cord-022526-j9kg00qf 2830 19 encompass encompass VB cord-022526-j9kg00qf 2830 20 the the DT cord-022526-j9kg00qf 2830 21 wide wide JJ cord-022526-j9kg00qf 2830 22 array array NN cord-022526-j9kg00qf 2830 23 of of IN cord-022526-j9kg00qf 2830 24 associated associated JJ cord-022526-j9kg00qf 2830 25 clinical clinical JJ cord-022526-j9kg00qf 2830 26 syndromes syndrome NNS cord-022526-j9kg00qf 2830 27 . . . cord-022526-j9kg00qf 2831 1 EGUS EGUS NNP cord-022526-j9kg00qf 2831 2 develops develop VBZ cord-022526-j9kg00qf 2831 3 in in IN cord-022526-j9kg00qf 2831 4 horses horse NNS cord-022526-j9kg00qf 2831 5 of of IN cord-022526-j9kg00qf 2831 6 all all DT cord-022526-j9kg00qf 2831 7 ages age NNS cord-022526-j9kg00qf 2831 8 and and CC cord-022526-j9kg00qf 2831 9 continues continue VBZ cord-022526-j9kg00qf 2831 10 to to TO cord-022526-j9kg00qf 2831 11 be be VB cord-022526-j9kg00qf 2831 12 of of IN cord-022526-j9kg00qf 2831 13 major major JJ cord-022526-j9kg00qf 2831 14 clinical clinical JJ cord-022526-j9kg00qf 2831 15 and and CC cord-022526-j9kg00qf 2831 16 economical economical JJ cord-022526-j9kg00qf 2831 17 importance importance NN cord-022526-j9kg00qf 2831 18 . . . cord-022526-j9kg00qf 2832 1 2 2 LS cord-022526-j9kg00qf 2833 1 The the DT cord-022526-j9kg00qf 2833 2 prevalence prevalence NN cord-022526-j9kg00qf 2833 3 of of IN cord-022526-j9kg00qf 2833 4 gastric gastric JJ cord-022526-j9kg00qf 2833 5 ulceration ulceration NN cord-022526-j9kg00qf 2833 6 has have VBZ cord-022526-j9kg00qf 2833 7 been be VBN cord-022526-j9kg00qf 2833 8 reported report VBN cord-022526-j9kg00qf 2833 9 for for IN cord-022526-j9kg00qf 2833 10 a a DT cord-022526-j9kg00qf 2833 11 variety variety NN cord-022526-j9kg00qf 2833 12 of of IN cord-022526-j9kg00qf 2833 13 breeds breed NNS cord-022526-j9kg00qf 2833 14 and and CC cord-022526-j9kg00qf 2833 15 types type NNS cord-022526-j9kg00qf 2833 16 of of IN cord-022526-j9kg00qf 2833 17 horses horse NNS cord-022526-j9kg00qf 2833 18 ; ; : cord-022526-j9kg00qf 2833 19 however however RB cord-022526-j9kg00qf 2833 20 , , , cord-022526-j9kg00qf 2833 21 most most JJS cord-022526-j9kg00qf 2833 22 current current JJ cord-022526-j9kg00qf 2833 23 data datum NNS cord-022526-j9kg00qf 2833 24 involve involve VBP cord-022526-j9kg00qf 2833 25 Thoroughbreds thoroughbred NNS cord-022526-j9kg00qf 2833 26 in in IN cord-022526-j9kg00qf 2833 27 race race NN cord-022526-j9kg00qf 2833 28 training training NN cord-022526-j9kg00qf 2833 29 . . . cord-022526-j9kg00qf 2834 1 The the DT cord-022526-j9kg00qf 2834 2 prevalence prevalence NN cord-022526-j9kg00qf 2834 3 of of IN cord-022526-j9kg00qf 2834 4 squamous squamous JJ cord-022526-j9kg00qf 2834 5 ulceration ulceration NN cord-022526-j9kg00qf 2834 6 in in IN cord-022526-j9kg00qf 2834 7 horses horse NNS cord-022526-j9kg00qf 2834 8 in in IN cord-022526-j9kg00qf 2834 9 race race NN cord-022526-j9kg00qf 2834 10 training training NN cord-022526-j9kg00qf 2834 11 varies vary VBZ cord-022526-j9kg00qf 2834 12 from from IN cord-022526-j9kg00qf 2834 13 70 70 CD cord-022526-j9kg00qf 2834 14 % % NN cord-022526-j9kg00qf 2834 15 to to IN cord-022526-j9kg00qf 2834 16 94 94 CD cord-022526-j9kg00qf 2834 17 % % NN cord-022526-j9kg00qf 2834 18 3 3 CD cord-022526-j9kg00qf 2834 19 - - SYM cord-022526-j9kg00qf 2834 20 8 8 CD cord-022526-j9kg00qf 2834 21 and and CC cord-022526-j9kg00qf 2834 22 can can MD cord-022526-j9kg00qf 2834 23 be be VB cord-022526-j9kg00qf 2834 24 as as RB cord-022526-j9kg00qf 2834 25 high high JJ cord-022526-j9kg00qf 2834 26 as as IN cord-022526-j9kg00qf 2834 27 100 100 CD cord-022526-j9kg00qf 2834 28 % % NN cord-022526-j9kg00qf 2834 29 when when WRB cord-022526-j9kg00qf 2834 30 limited limit VBN cord-022526-j9kg00qf 2834 31 to to IN cord-022526-j9kg00qf 2834 32 animals animal NNS cord-022526-j9kg00qf 2834 33 actively actively RB cord-022526-j9kg00qf 2834 34 racing race VBG cord-022526-j9kg00qf 2834 35 . . . cord-022526-j9kg00qf 2835 1 4 4 LS cord-022526-j9kg00qf 2836 1 In in IN cord-022526-j9kg00qf 2836 2 a a DT cord-022526-j9kg00qf 2836 3 survey survey NN cord-022526-j9kg00qf 2836 4 of of IN cord-022526-j9kg00qf 2836 5 50 50 CD cord-022526-j9kg00qf 2836 6 active active JJ cord-022526-j9kg00qf 2836 7 show show NN cord-022526-j9kg00qf 2836 8 horses horse NNS cord-022526-j9kg00qf 2836 9 , , , cord-022526-j9kg00qf 2836 10 58 58 CD cord-022526-j9kg00qf 2836 11 % % NN cord-022526-j9kg00qf 2836 12 had have VBD cord-022526-j9kg00qf 2836 13 gastric gastric JJ cord-022526-j9kg00qf 2836 14 ulceration ulceration NN cord-022526-j9kg00qf 2836 15 , , , cord-022526-j9kg00qf 2836 16 with with IN cord-022526-j9kg00qf 2836 17 only only RB cord-022526-j9kg00qf 2836 18 1 1 CD cord-022526-j9kg00qf 2836 19 horse horse NN cord-022526-j9kg00qf 2836 20 having have VBG cord-022526-j9kg00qf 2836 21 ulceration ulceration NN cord-022526-j9kg00qf 2836 22 of of IN cord-022526-j9kg00qf 2836 23 the the DT cord-022526-j9kg00qf 2836 24 glandular glandular JJ cord-022526-j9kg00qf 2836 25 fundus fundus NN cord-022526-j9kg00qf 2836 26 . . . cord-022526-j9kg00qf 2836 27 9 9 CD cord-022526-j9kg00qf 2837 1 In in IN cord-022526-j9kg00qf 2837 2 one one CD cord-022526-j9kg00qf 2837 3 large large JJ cord-022526-j9kg00qf 2837 4 retrospective retrospective JJ cord-022526-j9kg00qf 2837 5 study study NN cord-022526-j9kg00qf 2837 6 ( ( -LRB- cord-022526-j9kg00qf 2837 7 3715 3715 CD cord-022526-j9kg00qf 2837 8 adult adult NN cord-022526-j9kg00qf 2837 9 horses horse NNS cord-022526-j9kg00qf 2837 10 from from IN cord-022526-j9kg00qf 2837 11 1924 1924 CD cord-022526-j9kg00qf 2837 12 to to IN cord-022526-j9kg00qf 2837 13 1996 1996 CD cord-022526-j9kg00qf 2837 14 ) ) -RRB- cord-022526-j9kg00qf 2837 15 evaluating evaluate VBG cord-022526-j9kg00qf 2837 16 incidence incidence NN cord-022526-j9kg00qf 2837 17 of of IN cord-022526-j9kg00qf 2837 18 gastric gastric JJ cord-022526-j9kg00qf 2837 19 ulceration ulceration NN cord-022526-j9kg00qf 2837 20 identified identify VBN cord-022526-j9kg00qf 2837 21 at at IN cord-022526-j9kg00qf 2837 22 necropsy necropsy JJ cord-022526-j9kg00qf 2837 23 , , , cord-022526-j9kg00qf 2837 24 an an DT cord-022526-j9kg00qf 2837 25 overall overall JJ cord-022526-j9kg00qf 2837 26 prevalence prevalence NN cord-022526-j9kg00qf 2837 27 of of IN cord-022526-j9kg00qf 2837 28 10.3 10.3 CD cord-022526-j9kg00qf 2837 29 % % NN cord-022526-j9kg00qf 2837 30 was be VBD cord-022526-j9kg00qf 2837 31 found find VBN cord-022526-j9kg00qf 2837 32 . . . cord-022526-j9kg00qf 2838 1 The the DT cord-022526-j9kg00qf 2838 2 highest high JJS cord-022526-j9kg00qf 2838 3 prevalence prevalence NN cord-022526-j9kg00qf 2838 4 was be VBD cord-022526-j9kg00qf 2838 5 found find VBN cord-022526-j9kg00qf 2838 6 in in IN cord-022526-j9kg00qf 2838 7 Thoroughbreds thoroughbred NNS cord-022526-j9kg00qf 2838 8 ( ( -LRB- cord-022526-j9kg00qf 2838 9 including include VBG cord-022526-j9kg00qf 2838 10 Arabians Arabians NNPS cord-022526-j9kg00qf 2838 11 ) ) -RRB- cord-022526-j9kg00qf 2838 12 and and CC cord-022526-j9kg00qf 2838 13 Standardbred Standardbred NNP cord-022526-j9kg00qf 2838 14 trotters trotter NNS cord-022526-j9kg00qf 2838 15 , , , cord-022526-j9kg00qf 2838 16 and and CC cord-022526-j9kg00qf 2838 17 cold cold JJ cord-022526-j9kg00qf 2838 18 - - HYPH cord-022526-j9kg00qf 2838 19 blooded blooded JJ cord-022526-j9kg00qf 2838 20 horses horse NNS cord-022526-j9kg00qf 2838 21 were be VBD cord-022526-j9kg00qf 2838 22 affected affect VBN cord-022526-j9kg00qf 2838 23 significantly significantly RB cord-022526-j9kg00qf 2838 24 less less RBR cord-022526-j9kg00qf 2838 25 . . . cord-022526-j9kg00qf 2839 1 Lesions lesion NNS cord-022526-j9kg00qf 2839 2 were be VBD cord-022526-j9kg00qf 2839 3 located locate VBN cord-022526-j9kg00qf 2839 4 most most RBS cord-022526-j9kg00qf 2839 5 commonly commonly RB cord-022526-j9kg00qf 2839 6 in in IN cord-022526-j9kg00qf 2839 7 the the DT cord-022526-j9kg00qf 2839 8 squamous squamous JJ cord-022526-j9kg00qf 2839 9 mucosa mucosa NN cord-022526-j9kg00qf 2839 10 along along IN cord-022526-j9kg00qf 2839 11 the the DT cord-022526-j9kg00qf 2839 12 margo margo NNP cord-022526-j9kg00qf 2839 13 plicatus plicatus NNP cord-022526-j9kg00qf 2839 14 , , , cord-022526-j9kg00qf 2839 15 followed follow VBN cord-022526-j9kg00qf 2839 16 by by IN cord-022526-j9kg00qf 2839 17 the the DT cord-022526-j9kg00qf 2839 18 glandular glandular JJ cord-022526-j9kg00qf 2839 19 body body NN cord-022526-j9kg00qf 2839 20 , , , cord-022526-j9kg00qf 2839 21 proximal proximal JJ cord-022526-j9kg00qf 2839 22 squamous squamous JJ cord-022526-j9kg00qf 2839 23 mucosa mucosa NN cord-022526-j9kg00qf 2839 24 , , , cord-022526-j9kg00qf 2839 25 and and CC cord-022526-j9kg00qf 2839 26 antrum antrum NN cord-022526-j9kg00qf 2839 27 . . . cord-022526-j9kg00qf 2840 1 10 10 CD cord-022526-j9kg00qf 2841 1 Many many JJ cord-022526-j9kg00qf 2841 2 studies study NNS cord-022526-j9kg00qf 2841 3 investigating investigate VBG cord-022526-j9kg00qf 2841 4 prevalence prevalence NN cord-022526-j9kg00qf 2841 5 of of IN cord-022526-j9kg00qf 2841 6 gastric gastric JJ cord-022526-j9kg00qf 2841 7 ulceration ulceration NN cord-022526-j9kg00qf 2841 8 do do VBP cord-022526-j9kg00qf 2841 9 not not RB cord-022526-j9kg00qf 2841 10 differentiate differentiate VB cord-022526-j9kg00qf 2841 11 between between IN cord-022526-j9kg00qf 2841 12 squamous squamous JJ cord-022526-j9kg00qf 2841 13 and and CC cord-022526-j9kg00qf 2841 14 glandular glandular JJ cord-022526-j9kg00qf 2841 15 lesions lesion NNS cord-022526-j9kg00qf 2841 16 or or CC cord-022526-j9kg00qf 2841 17 evaluate evaluate VB cord-022526-j9kg00qf 2841 18 only only JJ cord-022526-j9kg00qf 2841 19 squamous squamous JJ cord-022526-j9kg00qf 2841 20 disease disease NN cord-022526-j9kg00qf 2841 21 . . . cord-022526-j9kg00qf 2842 1 In in IN cord-022526-j9kg00qf 2842 2 a a DT cord-022526-j9kg00qf 2842 3 recent recent JJ cord-022526-j9kg00qf 2842 4 study study NN cord-022526-j9kg00qf 2842 5 in in IN cord-022526-j9kg00qf 2842 6 which which WDT cord-022526-j9kg00qf 2842 7 the the DT cord-022526-j9kg00qf 2842 8 gastric gastric JJ cord-022526-j9kg00qf 2842 9 antrum antrum NN cord-022526-j9kg00qf 2842 10 and and CC cord-022526-j9kg00qf 2842 11 pylorus pylorus NNP cord-022526-j9kg00qf 2842 12 were be VBD cord-022526-j9kg00qf 2842 13 evaluated evaluate VBN cord-022526-j9kg00qf 2842 14 in in IN cord-022526-j9kg00qf 2842 15 162 162 CD cord-022526-j9kg00qf 2842 16 horses horse NNS cord-022526-j9kg00qf 2842 17 in in IN cord-022526-j9kg00qf 2842 18 a a DT cord-022526-j9kg00qf 2842 19 hospital hospital NN cord-022526-j9kg00qf 2842 20 setting setting NN cord-022526-j9kg00qf 2842 21 , , , cord-022526-j9kg00qf 2842 22 58 58 CD cord-022526-j9kg00qf 2842 23 % % NN cord-022526-j9kg00qf 2842 24 had have VBD cord-022526-j9kg00qf 2842 25 antral antral JJ cord-022526-j9kg00qf 2842 26 or or CC cord-022526-j9kg00qf 2842 27 pyloric pyloric JJ cord-022526-j9kg00qf 2842 28 erosions erosion NNS cord-022526-j9kg00qf 2842 29 or or CC cord-022526-j9kg00qf 2842 30 ulcerations ulceration NNS cord-022526-j9kg00qf 2842 31 , , , cord-022526-j9kg00qf 2842 32 58 58 CD cord-022526-j9kg00qf 2842 33 % % NN cord-022526-j9kg00qf 2842 34 had have VBD cord-022526-j9kg00qf 2842 35 squamous squamous JJ cord-022526-j9kg00qf 2842 36 mucosal mucosal JJ cord-022526-j9kg00qf 2842 37 lesions lesion NNS cord-022526-j9kg00qf 2842 38 , , , cord-022526-j9kg00qf 2842 39 and and CC cord-022526-j9kg00qf 2842 40 8 8 CD cord-022526-j9kg00qf 2842 41 % % NN cord-022526-j9kg00qf 2842 42 had have VBD cord-022526-j9kg00qf 2842 43 lesions lesion NNS cord-022526-j9kg00qf 2842 44 involving involve VBG cord-022526-j9kg00qf 2842 45 the the DT cord-022526-j9kg00qf 2842 46 glandular glandular JJ cord-022526-j9kg00qf 2842 47 body body NN cord-022526-j9kg00qf 2842 48 . . . cord-022526-j9kg00qf 2843 1 11 11 CD cord-022526-j9kg00qf 2844 1 A a DT cord-022526-j9kg00qf 2844 2 correlation correlation NN cord-022526-j9kg00qf 2844 3 between between IN cord-022526-j9kg00qf 2844 4 the the DT cord-022526-j9kg00qf 2844 5 presence presence NN cord-022526-j9kg00qf 2844 6 or or CC cord-022526-j9kg00qf 2844 7 severity severity NN cord-022526-j9kg00qf 2844 8 of of IN cord-022526-j9kg00qf 2844 9 squamous squamous JJ cord-022526-j9kg00qf 2844 10 disease disease NN cord-022526-j9kg00qf 2844 11 and and CC cord-022526-j9kg00qf 2844 12 antral antral JJ cord-022526-j9kg00qf 2844 13 / / SYM cord-022526-j9kg00qf 2844 14 pyloric pyloric JJ cord-022526-j9kg00qf 2844 15 disease disease NN cord-022526-j9kg00qf 2844 16 was be VBD cord-022526-j9kg00qf 2844 17 not not RB cord-022526-j9kg00qf 2844 18 identified identify VBN cord-022526-j9kg00qf 2844 19 . . . cord-022526-j9kg00qf 2845 1 The the DT cord-022526-j9kg00qf 2845 2 reported report VBN cord-022526-j9kg00qf 2845 3 prevalence prevalence NN cord-022526-j9kg00qf 2845 4 of of IN cord-022526-j9kg00qf 2845 5 gastric gastric JJ cord-022526-j9kg00qf 2845 6 ulceration ulceration NN cord-022526-j9kg00qf 2845 7 in in IN cord-022526-j9kg00qf 2845 8 foals foal NNS cord-022526-j9kg00qf 2845 9 varies vary VBZ cord-022526-j9kg00qf 2845 10 from from IN cord-022526-j9kg00qf 2845 11 25 25 CD cord-022526-j9kg00qf 2845 12 % % NN cord-022526-j9kg00qf 2845 13 to to IN cord-022526-j9kg00qf 2845 14 57 57 CD cord-022526-j9kg00qf 2845 15 % % NN cord-022526-j9kg00qf 2845 16 . . . cord-022526-j9kg00qf 2846 1 [ [ -LRB- cord-022526-j9kg00qf 2846 2 12 12 CD cord-022526-j9kg00qf 2846 3 ] ] -RRB- cord-022526-j9kg00qf 2846 4 [ [ -LRB- cord-022526-j9kg00qf 2846 5 13 13 CD cord-022526-j9kg00qf 2846 6 ] ] -RRB- cord-022526-j9kg00qf 2847 1 [ [ -LRB- cord-022526-j9kg00qf 2847 2 14 14 CD cord-022526-j9kg00qf 2847 3 ] ] -RRB- cord-022526-j9kg00qf 2847 4 _SP cord-022526-j9kg00qf 2847 5 An an DT cord-022526-j9kg00qf 2847 6 imbalance imbalance NN cord-022526-j9kg00qf 2847 7 between between IN cord-022526-j9kg00qf 2847 8 inciting incite VBG cord-022526-j9kg00qf 2847 9 and and CC cord-022526-j9kg00qf 2847 10 protective protective JJ cord-022526-j9kg00qf 2847 11 factors factor NNS cord-022526-j9kg00qf 2847 12 in in IN cord-022526-j9kg00qf 2847 13 the the DT cord-022526-j9kg00qf 2847 14 mucosal mucosal JJ cord-022526-j9kg00qf 2847 15 environment environment NN cord-022526-j9kg00qf 2847 16 can can MD cord-022526-j9kg00qf 2847 17 result result VB cord-022526-j9kg00qf 2847 18 in in IN cord-022526-j9kg00qf 2847 19 ulcer ulcer NN cord-022526-j9kg00qf 2847 20 formation formation NN cord-022526-j9kg00qf 2847 21 . . . cord-022526-j9kg00qf 2848 1 15 15 CD cord-022526-j9kg00qf 2848 2 , , , cord-022526-j9kg00qf 2848 3 16 16 CD cord-022526-j9kg00qf 2849 1 The the DT cord-022526-j9kg00qf 2849 2 major major JJ cord-022526-j9kg00qf 2849 3 intrinsic intrinsic JJ cord-022526-j9kg00qf 2849 4 factors factor NNS cord-022526-j9kg00qf 2849 5 promoting promote VBG cord-022526-j9kg00qf 2849 6 ulcer ulcer NN cord-022526-j9kg00qf 2849 7 formation formation NN cord-022526-j9kg00qf 2849 8 include include VBP cord-022526-j9kg00qf 2849 9 hydrochloric hydrochloric JJ cord-022526-j9kg00qf 2849 10 acid acid NN cord-022526-j9kg00qf 2849 11 , , , cord-022526-j9kg00qf 2849 12 bile bile NN cord-022526-j9kg00qf 2849 13 acids acid NNS cord-022526-j9kg00qf 2849 14 , , , cord-022526-j9kg00qf 2849 15 and and CC cord-022526-j9kg00qf 2849 16 pepsin pepsin NN cord-022526-j9kg00qf 2849 17 , , , cord-022526-j9kg00qf 2849 18 with with IN cord-022526-j9kg00qf 2849 19 hydrochloric hydrochloric JJ cord-022526-j9kg00qf 2849 20 acid acid NN cord-022526-j9kg00qf 2849 21 being be VBG cord-022526-j9kg00qf 2849 22 the the DT cord-022526-j9kg00qf 2849 23 predominant predominant JJ cord-022526-j9kg00qf 2849 24 factor factor NN cord-022526-j9kg00qf 2849 25 . . . cord-022526-j9kg00qf 2850 1 Various various JJ cord-022526-j9kg00qf 2850 2 intrinsic intrinsic JJ cord-022526-j9kg00qf 2850 3 factors factor NNS cord-022526-j9kg00qf 2850 4 protect protect VBP cord-022526-j9kg00qf 2850 5 against against IN cord-022526-j9kg00qf 2850 6 ulcer ulcer NN cord-022526-j9kg00qf 2850 7 formation formation NN cord-022526-j9kg00qf 2850 8 such such JJ cord-022526-j9kg00qf 2850 9 as as IN cord-022526-j9kg00qf 2850 10 the the DT cord-022526-j9kg00qf 2850 11 mucus mucus NN cord-022526-j9kg00qf 2850 12 - - HYPH cord-022526-j9kg00qf 2850 13 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2850 14 layer layer NN cord-022526-j9kg00qf 2850 15 , , , cord-022526-j9kg00qf 2850 16 maintenance maintenance NN cord-022526-j9kg00qf 2850 17 of of IN cord-022526-j9kg00qf 2850 18 adequate adequate JJ cord-022526-j9kg00qf 2850 19 mucosal mucosal JJ cord-022526-j9kg00qf 2850 20 blood blood NN cord-022526-j9kg00qf 2850 21 flow flow NN cord-022526-j9kg00qf 2850 22 , , , cord-022526-j9kg00qf 2850 23 mucosal mucosal JJ cord-022526-j9kg00qf 2850 24 prostaglandin prostaglandin NN cord-022526-j9kg00qf 2850 25 E e NN cord-022526-j9kg00qf 2850 26 2 2 CD cord-022526-j9kg00qf 2850 27 and and CC cord-022526-j9kg00qf 2850 28 epidermal epidermal JJ cord-022526-j9kg00qf 2850 29 growth growth NN cord-022526-j9kg00qf 2850 30 factor factor NN cord-022526-j9kg00qf 2850 31 production production NN cord-022526-j9kg00qf 2850 32 , , , cord-022526-j9kg00qf 2850 33 and and CC cord-022526-j9kg00qf 2850 34 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 2850 35 motility motility NN cord-022526-j9kg00qf 2850 36 . . . cord-022526-j9kg00qf 2851 1 In in IN cord-022526-j9kg00qf 2851 2 human human JJ cord-022526-j9kg00qf 2851 3 beings being NNS cord-022526-j9kg00qf 2851 4 , , , cord-022526-j9kg00qf 2851 5 extrinsic extrinsic JJ cord-022526-j9kg00qf 2851 6 ulcerogenic ulcerogenic JJ cord-022526-j9kg00qf 2851 7 factors factor NNS cord-022526-j9kg00qf 2851 8 include include VBP cord-022526-j9kg00qf 2851 9 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 2851 10 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2851 11 drugs drug NNS cord-022526-j9kg00qf 2851 12 , , , cord-022526-j9kg00qf 2851 13 Helicobacter helicobacter NN cord-022526-j9kg00qf 2851 14 pylori pylori NN cord-022526-j9kg00qf 2851 15 , , , cord-022526-j9kg00qf 2851 16 stress stress NN cord-022526-j9kg00qf 2851 17 , , , cord-022526-j9kg00qf 2851 18 changes change NNS cord-022526-j9kg00qf 2851 19 in in IN cord-022526-j9kg00qf 2851 20 diet diet NN cord-022526-j9kg00qf 2851 21 , , , cord-022526-j9kg00qf 2851 22 or or CC cord-022526-j9kg00qf 2851 23 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2851 24 disorders disorder NNS cord-022526-j9kg00qf 2851 25 , , , cord-022526-j9kg00qf 2851 26 especially especially RB cord-022526-j9kg00qf 2851 27 those those DT cord-022526-j9kg00qf 2851 28 resulting result VBG cord-022526-j9kg00qf 2851 29 in in IN cord-022526-j9kg00qf 2851 30 delayed delay VBN cord-022526-j9kg00qf 2851 31 gastric gastric JJ cord-022526-j9kg00qf 2851 32 emptying emptying NN cord-022526-j9kg00qf 2851 33 . . . cord-022526-j9kg00qf 2852 1 1 1 LS cord-022526-j9kg00qf 2853 1 In in IN cord-022526-j9kg00qf 2853 2 human human JJ cord-022526-j9kg00qf 2853 3 neonates neonate NNS cord-022526-j9kg00qf 2853 4 , , , cord-022526-j9kg00qf 2853 5 physiologic physiologic JJ cord-022526-j9kg00qf 2853 6 stress stress NN cord-022526-j9kg00qf 2853 7 associated associate VBN cord-022526-j9kg00qf 2853 8 with with IN cord-022526-j9kg00qf 2853 9 a a DT cord-022526-j9kg00qf 2853 10 major major JJ cord-022526-j9kg00qf 2853 11 primary primary JJ cord-022526-j9kg00qf 2853 12 illness illness NN cord-022526-j9kg00qf 2853 13 seems seem VBZ cord-022526-j9kg00qf 2853 14 to to TO cord-022526-j9kg00qf 2853 15 be be VB cord-022526-j9kg00qf 2853 16 associated associate VBN cord-022526-j9kg00qf 2853 17 strongly strongly RB cord-022526-j9kg00qf 2853 18 with with IN cord-022526-j9kg00qf 2853 19 gastric gastric JJ cord-022526-j9kg00qf 2853 20 ulcers ulcer NNS cord-022526-j9kg00qf 2853 21 . . . cord-022526-j9kg00qf 2854 1 17 17 CD cord-022526-j9kg00qf 2854 2 Many many JJ cord-022526-j9kg00qf 2854 3 of of IN cord-022526-j9kg00qf 2854 4 the the DT cord-022526-j9kg00qf 2854 5 other other JJ cord-022526-j9kg00qf 2854 6 factors factor NNS cord-022526-j9kg00qf 2854 7 mentioned mention VBN cord-022526-j9kg00qf 2854 8 previously previously RB cord-022526-j9kg00qf 2854 9 are be VBP cord-022526-j9kg00qf 2854 10 believed believe VBN cord-022526-j9kg00qf 2854 11 to to TO cord-022526-j9kg00qf 2854 12 be be VB cord-022526-j9kg00qf 2854 13 important important JJ cord-022526-j9kg00qf 2854 14 in in IN cord-022526-j9kg00qf 2854 15 horses horse NNS cord-022526-j9kg00qf 2854 16 , , , cord-022526-j9kg00qf 2854 17 but but CC cord-022526-j9kg00qf 2854 18 clear clear JJ cord-022526-j9kg00qf 2854 19 evidence evidence NN cord-022526-j9kg00qf 2854 20 of of IN cord-022526-j9kg00qf 2854 21 an an DT cord-022526-j9kg00qf 2854 22 infectious infectious JJ cord-022526-j9kg00qf 2854 23 agent agent NN cord-022526-j9kg00qf 2854 24 has have VBZ cord-022526-j9kg00qf 2854 25 not not RB cord-022526-j9kg00qf 2854 26 yet yet RB cord-022526-j9kg00qf 2854 27 been be VBN cord-022526-j9kg00qf 2854 28 identified identify VBN cord-022526-j9kg00qf 2854 29 in in IN cord-022526-j9kg00qf 2854 30 horses horse NNS cord-022526-j9kg00qf 2854 31 or or CC cord-022526-j9kg00qf 2854 32 foals foal NNS cord-022526-j9kg00qf 2854 33 with with IN cord-022526-j9kg00qf 2854 34 EGUS egu NNS cord-022526-j9kg00qf 2854 35 . . . cord-022526-j9kg00qf 2855 1 18 18 CD cord-022526-j9kg00qf 2855 2 , , , cord-022526-j9kg00qf 2855 3 19 19 CD cord-022526-j9kg00qf 2856 1 Recently recently RB cord-022526-j9kg00qf 2856 2 , , , cord-022526-j9kg00qf 2856 3 the the DT cord-022526-j9kg00qf 2856 4 possibility possibility NN cord-022526-j9kg00qf 2856 5 of of IN cord-022526-j9kg00qf 2856 6 Helicobacter Helicobacter NNP cord-022526-j9kg00qf 2856 7 infection infection NN cord-022526-j9kg00qf 2856 8 in in IN cord-022526-j9kg00qf 2856 9 horses horse NNS cord-022526-j9kg00qf 2856 10 has have VBZ cord-022526-j9kg00qf 2856 11 reemerged reemerge VBN cord-022526-j9kg00qf 2856 12 with with IN cord-022526-j9kg00qf 2856 13 the the DT cord-022526-j9kg00qf 2856 14 identification identification NN cord-022526-j9kg00qf 2856 15 of of IN cord-022526-j9kg00qf 2856 16 polymerase polymerase NN cord-022526-j9kg00qf 2856 17 chain chain NN cord-022526-j9kg00qf 2856 18 reaction reaction NN cord-022526-j9kg00qf 2856 19 products product NNS cord-022526-j9kg00qf 2856 20 from from IN cord-022526-j9kg00qf 2856 21 Urel Urel NNP cord-022526-j9kg00qf 2856 22 , , , cord-022526-j9kg00qf 2856 23 a a DT cord-022526-j9kg00qf 2856 24 protongated protongated JJ cord-022526-j9kg00qf 2856 25 urea urea NN cord-022526-j9kg00qf 2856 26 channel channel NN cord-022526-j9kg00qf 2856 27 unique unique JJ cord-022526-j9kg00qf 2856 28 to to IN cord-022526-j9kg00qf 2856 29 gastric gastric JJ cord-022526-j9kg00qf 2856 30 - - HYPH cord-022526-j9kg00qf 2856 31 dwelling dwell VBG cord-022526-j9kg00qf 2856 32 Helicobacter Helicobacter NNP cord-022526-j9kg00qf 2856 33 species specie NNS cord-022526-j9kg00qf 2856 34 , , , cord-022526-j9kg00qf 2856 35 in in IN cord-022526-j9kg00qf 2856 36 the the DT cord-022526-j9kg00qf 2856 37 squamous squamous JJ cord-022526-j9kg00qf 2856 38 epithelium epithelium NN cord-022526-j9kg00qf 2856 39 of of IN cord-022526-j9kg00qf 2856 40 three three CD cord-022526-j9kg00qf 2856 41 horses horse NNS cord-022526-j9kg00qf 2856 42 , , , cord-022526-j9kg00qf 2856 43 two two CD cord-022526-j9kg00qf 2856 44 of of IN cord-022526-j9kg00qf 2856 45 which which WDT cord-022526-j9kg00qf 2856 46 had have VBD cord-022526-j9kg00qf 2856 47 squamous squamous JJ cord-022526-j9kg00qf 2856 48 erosions erosion NNS cord-022526-j9kg00qf 2856 49 . . . cord-022526-j9kg00qf 2857 1 20 20 CD cord-022526-j9kg00qf 2858 1 The the DT cord-022526-j9kg00qf 2858 2 specific specific JJ cord-022526-j9kg00qf 2858 3 factors factor NNS cord-022526-j9kg00qf 2858 4 involved involve VBN cord-022526-j9kg00qf 2858 5 in in IN cord-022526-j9kg00qf 2858 6 injury injury NN cord-022526-j9kg00qf 2858 7 and and CC cord-022526-j9kg00qf 2858 8 the the DT cord-022526-j9kg00qf 2858 9 protective protective JJ cord-022526-j9kg00qf 2858 10 mechanisms mechanism NNS cord-022526-j9kg00qf 2858 11 vary vary VBP cord-022526-j9kg00qf 2858 12 between between IN cord-022526-j9kg00qf 2858 13 regions region NNS cord-022526-j9kg00qf 2858 14 of of IN cord-022526-j9kg00qf 2858 15 the the DT cord-022526-j9kg00qf 2858 16 proximal proximal JJ cord-022526-j9kg00qf 2858 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 2858 18 tract tract NN cord-022526-j9kg00qf 2858 19 . . . cord-022526-j9kg00qf 2859 1 The the DT cord-022526-j9kg00qf 2859 2 pathophysiology pathophysiology NN cord-022526-j9kg00qf 2859 3 of of IN cord-022526-j9kg00qf 2859 4 squamous squamous JJ cord-022526-j9kg00qf 2859 5 mucosal mucosal JJ cord-022526-j9kg00qf 2859 6 ulceration ulceration NN cord-022526-j9kg00qf 2859 7 in in IN cord-022526-j9kg00qf 2859 8 the the DT cord-022526-j9kg00qf 2859 9 horse horse NN cord-022526-j9kg00qf 2859 10 appears appear VBZ cord-022526-j9kg00qf 2859 11 similar similar JJ cord-022526-j9kg00qf 2859 12 to to IN cord-022526-j9kg00qf 2859 13 that that DT cord-022526-j9kg00qf 2859 14 in in IN cord-022526-j9kg00qf 2859 15 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2859 16 reflux reflux NN cord-022526-j9kg00qf 2859 17 disease disease NN cord-022526-j9kg00qf 2859 18 in in IN cord-022526-j9kg00qf 2859 19 human human JJ cord-022526-j9kg00qf 2859 20 beings being NNS cord-022526-j9kg00qf 2859 21 and and CC cord-022526-j9kg00qf 2859 22 ulceration ulceration NN cord-022526-j9kg00qf 2859 23 of of IN cord-022526-j9kg00qf 2859 24 the the DT cord-022526-j9kg00qf 2859 25 nonglandular nonglandular JJ cord-022526-j9kg00qf 2859 26 mucosa mucosa NN cord-022526-j9kg00qf 2859 27 in in IN cord-022526-j9kg00qf 2859 28 pigs pig NNS cord-022526-j9kg00qf 2859 29 . . . cord-022526-j9kg00qf 2860 1 Excess excess JJ cord-022526-j9kg00qf 2860 2 acid acid NN cord-022526-j9kg00qf 2860 3 exposure exposure NN cord-022526-j9kg00qf 2860 4 is be VBZ cord-022526-j9kg00qf 2860 5 the the DT cord-022526-j9kg00qf 2860 6 predominant predominant JJ cord-022526-j9kg00qf 2860 7 mechanism mechanism NN cord-022526-j9kg00qf 2860 8 responsible responsible JJ cord-022526-j9kg00qf 2860 9 for for IN cord-022526-j9kg00qf 2860 10 squamous squamous JJ cord-022526-j9kg00qf 2860 11 mucosal mucosal JJ cord-022526-j9kg00qf 2860 12 ulceration ulceration NN cord-022526-j9kg00qf 2860 13 , , , cord-022526-j9kg00qf 2860 14 although although IN cord-022526-j9kg00qf 2860 15 many many JJ cord-022526-j9kg00qf 2860 16 details detail NNS cord-022526-j9kg00qf 2860 17 remain remain VBP cord-022526-j9kg00qf 2860 18 unclear unclear JJ cord-022526-j9kg00qf 2860 19 . . . cord-022526-j9kg00qf 2861 1 21 21 CD cord-022526-j9kg00qf 2861 2 Hydrochloric hydrochloric JJ cord-022526-j9kg00qf 2861 3 acid acid NN cord-022526-j9kg00qf 2861 4 is be VBZ cord-022526-j9kg00qf 2861 5 secreted secrete VBN cord-022526-j9kg00qf 2861 6 by by IN cord-022526-j9kg00qf 2861 7 parietal parietal JJ cord-022526-j9kg00qf 2861 8 cells cell NNS cord-022526-j9kg00qf 2861 9 in in IN cord-022526-j9kg00qf 2861 10 the the DT cord-022526-j9kg00qf 2861 11 gastric gastric JJ cord-022526-j9kg00qf 2861 12 glands gland NNS cord-022526-j9kg00qf 2861 13 via via IN cord-022526-j9kg00qf 2861 14 a a DT cord-022526-j9kg00qf 2861 15 hydrogen hydrogen NN cord-022526-j9kg00qf 2861 16 - - HYPH cord-022526-j9kg00qf 2861 17 potassium potassium NN cord-022526-j9kg00qf 2861 18 adenosine adenosine NN cord-022526-j9kg00qf 2861 19 triphosphatase triphosphatase NN cord-022526-j9kg00qf 2861 20 ( ( -LRB- cord-022526-j9kg00qf 2861 21 H h NN cord-022526-j9kg00qf 2861 22 + + CC cord-022526-j9kg00qf 2861 23 , , , cord-022526-j9kg00qf 2861 24 K k NN cord-022526-j9kg00qf 2861 25 + + CC cord-022526-j9kg00qf 2861 26 -ATPase -atpase NN cord-022526-j9kg00qf 2861 27 ) ) -RRB- cord-022526-j9kg00qf 2861 28 pump pump VB cord-022526-j9kg00qf 2861 29 on on IN cord-022526-j9kg00qf 2861 30 the the DT cord-022526-j9kg00qf 2861 31 luminal luminal JJ cord-022526-j9kg00qf 2861 32 side side NN cord-022526-j9kg00qf 2861 33 . . . cord-022526-j9kg00qf 2862 1 Horses horse NNS cord-022526-j9kg00qf 2862 2 secrete secrete VBP cord-022526-j9kg00qf 2862 3 acid acid NN cord-022526-j9kg00qf 2862 4 continuously continuously RB cord-022526-j9kg00qf 2862 5 , , , cord-022526-j9kg00qf 2862 6 and and CC cord-022526-j9kg00qf 2862 7 measured measure VBN cord-022526-j9kg00qf 2862 8 pH ph NN cord-022526-j9kg00qf 2862 9 of of IN cord-022526-j9kg00qf 2862 10 equine equine JJ cord-022526-j9kg00qf 2862 11 gastric gastric JJ cord-022526-j9kg00qf 2862 12 contents content NNS cord-022526-j9kg00qf 2862 13 varies vary VBZ cord-022526-j9kg00qf 2862 14 from from IN cord-022526-j9kg00qf 2862 15 less less JJR cord-022526-j9kg00qf 2862 16 than than IN cord-022526-j9kg00qf 2862 17 2 2 CD cord-022526-j9kg00qf 2862 18 to to IN cord-022526-j9kg00qf 2862 19 greater great JJR cord-022526-j9kg00qf 2862 20 than than IN cord-022526-j9kg00qf 2862 21 6 6 CD cord-022526-j9kg00qf 2862 22 depending depend VBG cord-022526-j9kg00qf 2862 23 on on IN cord-022526-j9kg00qf 2862 24 the the DT cord-022526-j9kg00qf 2862 25 dietary dietary JJ cord-022526-j9kg00qf 2862 26 state state NN cord-022526-j9kg00qf 2862 27 of of IN cord-022526-j9kg00qf 2862 28 the the DT cord-022526-j9kg00qf 2862 29 horse horse NN cord-022526-j9kg00qf 2862 30 ( ( -LRB- cord-022526-j9kg00qf 2862 31 fed feed VBN cord-022526-j9kg00qf 2862 32 or or CC cord-022526-j9kg00qf 2862 33 fasted fast VBD cord-022526-j9kg00qf 2862 34 ) ) -RRB- cord-022526-j9kg00qf 2862 35 . . . cord-022526-j9kg00qf 2863 1 22,23 22,23 CD cord-022526-j9kg00qf 2864 1 A a DT cord-022526-j9kg00qf 2864 2 protocol protocol NN cord-022526-j9kg00qf 2864 3 of of IN cord-022526-j9kg00qf 2864 4 repeated repeat VBN cord-022526-j9kg00qf 2864 5 24-hour 24-hour JJ cord-022526-j9kg00qf 2864 6 periods period NNS cord-022526-j9kg00qf 2864 7 of of IN cord-022526-j9kg00qf 2864 8 fasting fasting NN cord-022526-j9kg00qf 2864 9 and and CC cord-022526-j9kg00qf 2864 10 feeding feeding NN cord-022526-j9kg00qf 2864 11 has have VBZ cord-022526-j9kg00qf 2864 12 been be VBN cord-022526-j9kg00qf 2864 13 shown show VBN cord-022526-j9kg00qf 2864 14 to to TO cord-022526-j9kg00qf 2864 15 induce induce VB cord-022526-j9kg00qf 2864 16 squamous squamous JJ cord-022526-j9kg00qf 2864 17 erosion erosion NN cord-022526-j9kg00qf 2864 18 and and CC cord-022526-j9kg00qf 2864 19 ulceration ulceration NN cord-022526-j9kg00qf 2864 20 . . . cord-022526-j9kg00qf 2865 1 24 24 CD cord-022526-j9kg00qf 2866 1 Because because IN cord-022526-j9kg00qf 2866 2 this this DT cord-022526-j9kg00qf 2866 3 protocol protocol NN cord-022526-j9kg00qf 2866 4 results result NNS cord-022526-j9kg00qf 2866 5 in in IN cord-022526-j9kg00qf 2866 6 periods period NNS cord-022526-j9kg00qf 2866 7 of of IN cord-022526-j9kg00qf 2866 8 prolonged prolonged JJ cord-022526-j9kg00qf 2866 9 gastric gastric JJ cord-022526-j9kg00qf 2866 10 acidity acidity NN cord-022526-j9kg00qf 2866 11 ( ( -LRB- cord-022526-j9kg00qf 2866 12 pH ph XX cord-022526-j9kg00qf 2866 13 < < XX cord-022526-j9kg00qf 2866 14 2.0 2.0 CD cord-022526-j9kg00qf 2866 15 ) ) -RRB- cord-022526-j9kg00qf 2866 16 and and CC cord-022526-j9kg00qf 2866 17 because because IN cord-022526-j9kg00qf 2866 18 concurrent concurrent JJ cord-022526-j9kg00qf 2866 19 administration administration NN cord-022526-j9kg00qf 2866 20 of of IN cord-022526-j9kg00qf 2866 21 the the DT cord-022526-j9kg00qf 2866 22 histamine histamine NN cord-022526-j9kg00qf 2866 23 2 2 CD cord-022526-j9kg00qf 2867 1 ( ( -LRB- cord-022526-j9kg00qf 2867 2 H h NN cord-022526-j9kg00qf 2867 3 2 2 CD cord-022526-j9kg00qf 2867 4 ) ) -RRB- cord-022526-j9kg00qf 2867 5 receptor receptor NN cord-022526-j9kg00qf 2867 6 antagonist antagonist NN cord-022526-j9kg00qf 2867 7 ranitidine ranitidine NN cord-022526-j9kg00qf 2867 8 reduces reduce VBZ cord-022526-j9kg00qf 2867 9 lesion lesion NN cord-022526-j9kg00qf 2867 10 severity severity NN cord-022526-j9kg00qf 2867 11 , , , cord-022526-j9kg00qf 2867 12 the the DT cord-022526-j9kg00qf 2867 13 protocol protocol NN cord-022526-j9kg00qf 2867 14 supports support VBZ cord-022526-j9kg00qf 2867 15 the the DT cord-022526-j9kg00qf 2867 16 role role NN cord-022526-j9kg00qf 2867 17 of of IN cord-022526-j9kg00qf 2867 18 acid acid JJ cord-022526-j9kg00qf 2867 19 exposure exposure NN cord-022526-j9kg00qf 2867 20 in in IN cord-022526-j9kg00qf 2867 21 the the DT cord-022526-j9kg00qf 2867 22 pathogenesis pathogenesis NN cord-022526-j9kg00qf 2867 23 of of IN cord-022526-j9kg00qf 2867 24 squamous squamous JJ cord-022526-j9kg00qf 2867 25 ulcer ulcer NN cord-022526-j9kg00qf 2867 26 disease disease NN cord-022526-j9kg00qf 2867 27 . . . cord-022526-j9kg00qf 2868 1 Several several JJ cord-022526-j9kg00qf 2868 2 peptides peptide NNS cord-022526-j9kg00qf 2868 3 can can MD cord-022526-j9kg00qf 2868 4 stimulate stimulate VB cord-022526-j9kg00qf 2868 5 or or CC cord-022526-j9kg00qf 2868 6 inhibit inhibit VB cord-022526-j9kg00qf 2868 7 parietal parietal JJ cord-022526-j9kg00qf 2868 8 cell cell NN cord-022526-j9kg00qf 2868 9 secretion secretion NN cord-022526-j9kg00qf 2868 10 of of IN cord-022526-j9kg00qf 2868 11 acid acid NN cord-022526-j9kg00qf 2868 12 . . . cord-022526-j9kg00qf 2869 1 The the DT cord-022526-j9kg00qf 2869 2 predominant predominant JJ cord-022526-j9kg00qf 2869 3 stimuli stimulus NNS cord-022526-j9kg00qf 2869 4 for for IN cord-022526-j9kg00qf 2869 5 hydrochloric hydrochloric JJ cord-022526-j9kg00qf 2869 6 acid acid NN cord-022526-j9kg00qf 2869 7 secretion secretion NN cord-022526-j9kg00qf 2869 8 are be VBP cord-022526-j9kg00qf 2869 9 gastrin gastrin NN cord-022526-j9kg00qf 2869 10 , , , cord-022526-j9kg00qf 2869 11 histamine histamine NN cord-022526-j9kg00qf 2869 12 , , , cord-022526-j9kg00qf 2869 13 and and CC cord-022526-j9kg00qf 2869 14 acetylcholine acetylcholine NN cord-022526-j9kg00qf 2869 15 via via IN cord-022526-j9kg00qf 2869 16 the the DT cord-022526-j9kg00qf 2869 17 vagus vagus NN cord-022526-j9kg00qf 2869 18 nerve nerve NN cord-022526-j9kg00qf 2869 19 . . . cord-022526-j9kg00qf 2870 1 1 1 CD cord-022526-j9kg00qf 2870 2 G g NN cord-022526-j9kg00qf 2870 3 cells cell NNS cord-022526-j9kg00qf 2870 4 release release VBP cord-022526-j9kg00qf 2870 5 gastrin gastrin NN cord-022526-j9kg00qf 2870 6 within within IN cord-022526-j9kg00qf 2870 7 the the DT cord-022526-j9kg00qf 2870 8 antral antral JJ cord-022526-j9kg00qf 2870 9 mucosa mucosa NN cord-022526-j9kg00qf 2870 10 , , , cord-022526-j9kg00qf 2870 11 whereas whereas IN cord-022526-j9kg00qf 2870 12 mast mast NN cord-022526-j9kg00qf 2870 13 cells cell NNS cord-022526-j9kg00qf 2870 14 and and CC cord-022526-j9kg00qf 2870 15 enterochromaffin enterochromaffin NN cord-022526-j9kg00qf 2870 16 - - HYPH cord-022526-j9kg00qf 2870 17 like like JJ cord-022526-j9kg00qf 2870 18 cells cell NNS cord-022526-j9kg00qf 2870 19 release release VBP cord-022526-j9kg00qf 2870 20 histamine histamine NN cord-022526-j9kg00qf 2870 21 in in IN cord-022526-j9kg00qf 2870 22 the the DT cord-022526-j9kg00qf 2870 23 gastric gastric JJ cord-022526-j9kg00qf 2870 24 gland gland NN cord-022526-j9kg00qf 2870 25 . . . cord-022526-j9kg00qf 2871 1 Histamine histamine NN cord-022526-j9kg00qf 2871 2 binds bind VBZ cord-022526-j9kg00qf 2871 3 to to IN cord-022526-j9kg00qf 2871 4 type type NN cord-022526-j9kg00qf 2871 5 2 2 CD cord-022526-j9kg00qf 2871 6 receptors receptor NNS cord-022526-j9kg00qf 2871 7 on on IN cord-022526-j9kg00qf 2871 8 the the DT cord-022526-j9kg00qf 2871 9 parietal parietal JJ cord-022526-j9kg00qf 2871 10 cell cell NN cord-022526-j9kg00qf 2871 11 membrane membrane NN cord-022526-j9kg00qf 2871 12 , , , cord-022526-j9kg00qf 2871 13 causing cause VBG cord-022526-j9kg00qf 2871 14 an an DT cord-022526-j9kg00qf 2871 15 increase increase NN cord-022526-j9kg00qf 2871 16 in in IN cord-022526-j9kg00qf 2871 17 cyclic cyclic JJ cord-022526-j9kg00qf 2871 18 adenosine adenosine NN cord-022526-j9kg00qf 2871 19 monophosphate monophosphate NN cord-022526-j9kg00qf 2871 20 and and CC cord-022526-j9kg00qf 2871 21 resulting result VBG cord-022526-j9kg00qf 2871 22 in in IN cord-022526-j9kg00qf 2871 23 phosphorylation phosphorylation NN cord-022526-j9kg00qf 2871 24 of of IN cord-022526-j9kg00qf 2871 25 enzymes enzyme NNS cord-022526-j9kg00qf 2871 26 that that WDT cord-022526-j9kg00qf 2871 27 activate activate VBP cord-022526-j9kg00qf 2871 28 the the DT cord-022526-j9kg00qf 2871 29 proton proton NN cord-022526-j9kg00qf 2871 30 pump pump NN cord-022526-j9kg00qf 2871 31 . . . cord-022526-j9kg00qf 2872 1 Gastrin Gastrin NNP cord-022526-j9kg00qf 2872 2 and and CC cord-022526-j9kg00qf 2872 3 acetylcholine acetylcholine NN cord-022526-j9kg00qf 2872 4 can can MD cord-022526-j9kg00qf 2872 5 act act VB cord-022526-j9kg00qf 2872 6 via via IN cord-022526-j9kg00qf 2872 7 calcium calcium NN cord-022526-j9kg00qf 2872 8 - - HYPH cord-022526-j9kg00qf 2872 9 mediated mediate VBN cord-022526-j9kg00qf 2872 10 intracellular intracellular JJ cord-022526-j9kg00qf 2872 11 pathways pathway NNS cord-022526-j9kg00qf 2872 12 and and CC cord-022526-j9kg00qf 2872 13 also also RB cord-022526-j9kg00qf 2872 14 stimulate stimulate VB cord-022526-j9kg00qf 2872 15 histamine histamine NN cord-022526-j9kg00qf 2872 16 release release NN cord-022526-j9kg00qf 2872 17 directly directly RB cord-022526-j9kg00qf 2872 18 . . . cord-022526-j9kg00qf 2873 1 25 25 CD cord-022526-j9kg00qf 2874 1 Isolated isolated JJ cord-022526-j9kg00qf 2874 2 equine equine JJ cord-022526-j9kg00qf 2874 3 parietal parietal JJ cord-022526-j9kg00qf 2874 4 cells cell NNS cord-022526-j9kg00qf 2874 5 respond respond VBP cord-022526-j9kg00qf 2874 6 maximally maximally RB cord-022526-j9kg00qf 2874 7 to to IN cord-022526-j9kg00qf 2874 8 histamine histamine VB cord-022526-j9kg00qf 2874 9 stimulation stimulation NN cord-022526-j9kg00qf 2874 10 and and CC cord-022526-j9kg00qf 2874 11 only only RB cord-022526-j9kg00qf 2874 12 minimally minimally RB cord-022526-j9kg00qf 2874 13 to to TO cord-022526-j9kg00qf 2874 14 carbachol carbachol NNP cord-022526-j9kg00qf 2874 15 and and CC cord-022526-j9kg00qf 2874 16 pentagastrin pentagastrin NNP cord-022526-j9kg00qf 2874 17 . . . cord-022526-j9kg00qf 2875 1 26 26 CD cord-022526-j9kg00qf 2875 2 Gastrin Gastrin NNP cord-022526-j9kg00qf 2875 3 release release NN cord-022526-j9kg00qf 2875 4 is be VBZ cord-022526-j9kg00qf 2875 5 controlled control VBN cord-022526-j9kg00qf 2875 6 primarily primarily RB cord-022526-j9kg00qf 2875 7 by by IN cord-022526-j9kg00qf 2875 8 gastrin gastrin NN cord-022526-j9kg00qf 2875 9 - - HYPH cord-022526-j9kg00qf 2875 10 releasing release VBG cord-022526-j9kg00qf 2875 11 peptide peptide NN cord-022526-j9kg00qf 2875 12 , , , cord-022526-j9kg00qf 2875 13 which which WDT cord-022526-j9kg00qf 2875 14 is be VBZ cord-022526-j9kg00qf 2875 15 stimulated stimulate VBN cord-022526-j9kg00qf 2875 16 by by IN cord-022526-j9kg00qf 2875 17 gastric gastric JJ cord-022526-j9kg00qf 2875 18 distention distention NN cord-022526-j9kg00qf 2875 19 and and CC cord-022526-j9kg00qf 2875 20 increased increase VBN cord-022526-j9kg00qf 2875 21 luminal luminal JJ cord-022526-j9kg00qf 2875 22 pH ph NN cord-022526-j9kg00qf 2875 23 , , , cord-022526-j9kg00qf 2875 24 but but CC cord-022526-j9kg00qf 2875 25 the the DT cord-022526-j9kg00qf 2875 26 interaction interaction NN cord-022526-j9kg00qf 2875 27 between between IN cord-022526-j9kg00qf 2875 28 gastrin gastrin NN cord-022526-j9kg00qf 2875 29 and and CC cord-022526-j9kg00qf 2875 30 histamine histamine NN cord-022526-j9kg00qf 2875 31 has have VBZ cord-022526-j9kg00qf 2875 32 not not RB cord-022526-j9kg00qf 2875 33 been be VBN cord-022526-j9kg00qf 2875 34 elucidated elucidate VBN cord-022526-j9kg00qf 2875 35 fully fully RB cord-022526-j9kg00qf 2875 36 in in IN cord-022526-j9kg00qf 2875 37 the the DT cord-022526-j9kg00qf 2875 38 horse horse NN cord-022526-j9kg00qf 2875 39 . . . cord-022526-j9kg00qf 2876 1 Somatostatin somatostatin NN cord-022526-j9kg00qf 2876 2 , , , cord-022526-j9kg00qf 2876 3 released release VBN cord-022526-j9kg00qf 2876 4 by by IN cord-022526-j9kg00qf 2876 5 fundic fundic JJ cord-022526-j9kg00qf 2876 6 and and CC cord-022526-j9kg00qf 2876 7 antral antral JJ cord-022526-j9kg00qf 2876 8 D d NN cord-022526-j9kg00qf 2876 9 cells cell NNS cord-022526-j9kg00qf 2876 10 , , , cord-022526-j9kg00qf 2876 11 is be VBZ cord-022526-j9kg00qf 2876 12 the the DT cord-022526-j9kg00qf 2876 13 primary primary JJ cord-022526-j9kg00qf 2876 14 inhibitor inhibitor NN cord-022526-j9kg00qf 2876 15 of of IN cord-022526-j9kg00qf 2876 16 gastric gastric JJ cord-022526-j9kg00qf 2876 17 acid acid NN cord-022526-j9kg00qf 2876 18 secretion secretion NN cord-022526-j9kg00qf 2876 19 by by IN cord-022526-j9kg00qf 2876 20 parietal parietal JJ cord-022526-j9kg00qf 2876 21 cells cell NNS cord-022526-j9kg00qf 2876 22 . . . cord-022526-j9kg00qf 2877 1 The the DT cord-022526-j9kg00qf 2877 2 inhibitory inhibitory JJ cord-022526-j9kg00qf 2877 3 effect effect NN cord-022526-j9kg00qf 2877 4 of of IN cord-022526-j9kg00qf 2877 5 somatostatin somatostatin NN cord-022526-j9kg00qf 2877 6 is be VBZ cord-022526-j9kg00qf 2877 7 primarily primarily RB cord-022526-j9kg00qf 2877 8 paracrine paracrine JJ cord-022526-j9kg00qf 2877 9 , , , cord-022526-j9kg00qf 2877 10 but but CC cord-022526-j9kg00qf 2877 11 plasma plasma NN cord-022526-j9kg00qf 2877 12 levels level NNS cord-022526-j9kg00qf 2877 13 of of IN cord-022526-j9kg00qf 2877 14 somatostatin somatostatin NN cord-022526-j9kg00qf 2877 15 negatively negatively RB cord-022526-j9kg00qf 2877 16 correlate correlate VBP cord-022526-j9kg00qf 2877 17 with with IN cord-022526-j9kg00qf 2877 18 gastric gastric JJ cord-022526-j9kg00qf 2877 19 luminal luminal JJ cord-022526-j9kg00qf 2877 20 acidity acidity NN cord-022526-j9kg00qf 2877 21 . . . cord-022526-j9kg00qf 2878 1 27 27 CD cord-022526-j9kg00qf 2878 2 Epidermal epidermal JJ cord-022526-j9kg00qf 2878 3 growth growth NN cord-022526-j9kg00qf 2878 4 factor factor NN cord-022526-j9kg00qf 2878 5 , , , cord-022526-j9kg00qf 2878 6 a a DT cord-022526-j9kg00qf 2878 7 peptide peptide NN cord-022526-j9kg00qf 2878 8 produced produce VBN cord-022526-j9kg00qf 2878 9 in in IN cord-022526-j9kg00qf 2878 10 saliva saliva NN cord-022526-j9kg00qf 2878 11 , , , cord-022526-j9kg00qf 2878 12 also also RB cord-022526-j9kg00qf 2878 13 inhibits inhibit VBZ cord-022526-j9kg00qf 2878 14 gastric gastric JJ cord-022526-j9kg00qf 2878 15 acid acid NN cord-022526-j9kg00qf 2878 16 secretion secretion NN cord-022526-j9kg00qf 2878 17 . . . cord-022526-j9kg00qf 2879 1 28 28 CD cord-022526-j9kg00qf 2879 2 Foals foal NNS cord-022526-j9kg00qf 2879 3 can can MD cord-022526-j9kg00qf 2879 4 produce produce VB cord-022526-j9kg00qf 2879 5 significant significant JJ cord-022526-j9kg00qf 2879 6 amounts amount NNS cord-022526-j9kg00qf 2879 7 of of IN cord-022526-j9kg00qf 2879 8 gastric gastric JJ cord-022526-j9kg00qf 2879 9 acid acid NN cord-022526-j9kg00qf 2879 10 by by IN cord-022526-j9kg00qf 2879 11 the the DT cord-022526-j9kg00qf 2879 12 second second JJ cord-022526-j9kg00qf 2879 13 day day NN cord-022526-j9kg00qf 2879 14 of of IN cord-022526-j9kg00qf 2879 15 life life NN cord-022526-j9kg00qf 2879 16 , , , cord-022526-j9kg00qf 2879 17 with with IN cord-022526-j9kg00qf 2879 18 consistent consistent JJ cord-022526-j9kg00qf 2879 19 periods period NNS cord-022526-j9kg00qf 2879 20 of of IN cord-022526-j9kg00qf 2879 21 acidity acidity NN cord-022526-j9kg00qf 2879 22 ( ( -LRB- cord-022526-j9kg00qf 2879 23 pH ph XX cord-022526-j9kg00qf 2879 24 < < XX cord-022526-j9kg00qf 2879 25 2.0 2.0 CD cord-022526-j9kg00qf 2879 26 ) ) -RRB- cord-022526-j9kg00qf 2879 27 in in IN cord-022526-j9kg00qf 2879 28 clinically clinically RB cord-022526-j9kg00qf 2879 29 normal normal JJ cord-022526-j9kg00qf 2879 30 animals animal NNS cord-022526-j9kg00qf 2879 31 . . . cord-022526-j9kg00qf 2880 1 29 29 CD cord-022526-j9kg00qf 2880 2 , , , cord-022526-j9kg00qf 2880 3 30 30 CD cord-022526-j9kg00qf 2880 4 In in IN cord-022526-j9kg00qf 2880 5 one one CD cord-022526-j9kg00qf 2880 6 study study NN cord-022526-j9kg00qf 2880 7 , , , cord-022526-j9kg00qf 2880 8 foals foal NNS cord-022526-j9kg00qf 2880 9 tended tend VBD cord-022526-j9kg00qf 2880 10 to to TO cord-022526-j9kg00qf 2880 11 have have VB cord-022526-j9kg00qf 2880 12 a a DT cord-022526-j9kg00qf 2880 13 high high JJ cord-022526-j9kg00qf 2880 14 gastric gastric JJ cord-022526-j9kg00qf 2880 15 pH ph NN cord-022526-j9kg00qf 2880 16 at at IN cord-022526-j9kg00qf 2880 17 day day NN cord-022526-j9kg00qf 2880 18 1 1 CD cord-022526-j9kg00qf 2880 19 of of IN cord-022526-j9kg00qf 2880 20 age age NN cord-022526-j9kg00qf 2880 21 , , , cord-022526-j9kg00qf 2880 22 30 30 CD cord-022526-j9kg00qf 2880 23 but but CC cord-022526-j9kg00qf 2880 24 in in IN cord-022526-j9kg00qf 2880 25 a a DT cord-022526-j9kg00qf 2880 26 study study NN cord-022526-j9kg00qf 2880 27 of of IN cord-022526-j9kg00qf 2880 28 critically critically RB cord-022526-j9kg00qf 2880 29 ill ill JJ cord-022526-j9kg00qf 2880 30 foals foal NNS cord-022526-j9kg00qf 2880 31 , , , cord-022526-j9kg00qf 2880 32 some some DT cord-022526-j9kg00qf 2880 33 foals foal NNS cord-022526-j9kg00qf 2880 34 demonstrated demonstrate VBD cord-022526-j9kg00qf 2880 35 periods period NNS cord-022526-j9kg00qf 2880 36 of of IN cord-022526-j9kg00qf 2880 37 gastric gastric JJ cord-022526-j9kg00qf 2880 38 acidity acidity NN cord-022526-j9kg00qf 2880 39 on on IN cord-022526-j9kg00qf 2880 40 the the DT cord-022526-j9kg00qf 2880 41 first first JJ cord-022526-j9kg00qf 2880 42 day day NN cord-022526-j9kg00qf 2880 43 of of IN cord-022526-j9kg00qf 2880 44 life life NN cord-022526-j9kg00qf 2880 45 . . . cord-022526-j9kg00qf 2881 1 31 31 CD cord-022526-j9kg00qf 2882 1 Suckling suckle VBG cord-022526-j9kg00qf 2882 2 was be VBD cord-022526-j9kg00qf 2882 3 associated associate VBN cord-022526-j9kg00qf 2882 4 with with IN cord-022526-j9kg00qf 2882 5 an an DT cord-022526-j9kg00qf 2882 6 immediate immediate JJ cord-022526-j9kg00qf 2882 7 rise rise NN cord-022526-j9kg00qf 2882 8 in in IN cord-022526-j9kg00qf 2882 9 gastric gastric JJ cord-022526-j9kg00qf 2882 10 pH ph NN cord-022526-j9kg00qf 2882 11 , , , cord-022526-j9kg00qf 2882 12 whereas whereas IN cord-022526-j9kg00qf 2882 13 periods period NNS cord-022526-j9kg00qf 2882 14 of of IN cord-022526-j9kg00qf 2882 15 rest rest NN cord-022526-j9kg00qf 2882 16 in in IN cord-022526-j9kg00qf 2882 17 which which WDT cord-022526-j9kg00qf 2882 18 foals foal NNS cord-022526-j9kg00qf 2882 19 did do VBD cord-022526-j9kg00qf 2882 20 not not RB cord-022526-j9kg00qf 2882 21 suck suck VB cord-022526-j9kg00qf 2882 22 for for IN cord-022526-j9kg00qf 2882 23 more more JJR cord-022526-j9kg00qf 2882 24 than than IN cord-022526-j9kg00qf 2882 25 20 20 CD cord-022526-j9kg00qf 2882 26 minutes minute NNS cord-022526-j9kg00qf 2882 27 were be VBD cord-022526-j9kg00qf 2882 28 associated associate VBN cord-022526-j9kg00qf 2882 29 with with IN cord-022526-j9kg00qf 2882 30 prolonged prolonged JJ cord-022526-j9kg00qf 2882 31 periods period NNS cord-022526-j9kg00qf 2882 32 of of IN cord-022526-j9kg00qf 2882 33 acidity acidity NN cord-022526-j9kg00qf 2882 34 . . . cord-022526-j9kg00qf 2883 1 29 29 CD cord-022526-j9kg00qf 2884 1 Whereas whereas IN cord-022526-j9kg00qf 2884 2 premature premature JJ cord-022526-j9kg00qf 2884 3 human human JJ cord-022526-j9kg00qf 2884 4 infants infant NNS cord-022526-j9kg00qf 2884 5 are be VBP cord-022526-j9kg00qf 2884 6 capable capable JJ cord-022526-j9kg00qf 2884 7 of of IN cord-022526-j9kg00qf 2884 8 gastric gastric JJ cord-022526-j9kg00qf 2884 9 acid acid NN cord-022526-j9kg00qf 2884 10 production production NN cord-022526-j9kg00qf 2884 11 at at IN cord-022526-j9kg00qf 2884 12 28 28 CD cord-022526-j9kg00qf 2884 13 weeks week NNS cord-022526-j9kg00qf 2884 14 of of IN cord-022526-j9kg00qf 2884 15 gestation gestation NN cord-022526-j9kg00qf 2884 16 , , , cord-022526-j9kg00qf 2884 17 32 32 CD cord-022526-j9kg00qf 2884 18 only only RB cord-022526-j9kg00qf 2884 19 1 1 CD cord-022526-j9kg00qf 2884 20 of of IN cord-022526-j9kg00qf 2884 21 7 7 CD cord-022526-j9kg00qf 2884 22 premature premature JJ cord-022526-j9kg00qf 2884 23 foals foal NNS cord-022526-j9kg00qf 2884 24 demonstrated demonstrate VBD cord-022526-j9kg00qf 2884 25 an an DT cord-022526-j9kg00qf 2884 26 acidic acidic JJ cord-022526-j9kg00qf 2884 27 pH ph NN cord-022526-j9kg00qf 2884 28 recording recording NN cord-022526-j9kg00qf 2884 29 in in IN cord-022526-j9kg00qf 2884 30 a a DT cord-022526-j9kg00qf 2884 31 study study NN cord-022526-j9kg00qf 2884 32 of of IN cord-022526-j9kg00qf 2884 33 gastric gastric JJ cord-022526-j9kg00qf 2884 34 pH pH NNP cord-022526-j9kg00qf 2884 35 profiles profile NNS cord-022526-j9kg00qf 2884 36 in in IN cord-022526-j9kg00qf 2884 37 critically critically RB cord-022526-j9kg00qf 2884 38 ill ill JJ cord-022526-j9kg00qf 2884 39 foals foal NNS cord-022526-j9kg00qf 2884 40 . . . cord-022526-j9kg00qf 2885 1 31 31 CD cord-022526-j9kg00qf 2886 1 However however RB cord-022526-j9kg00qf 2886 2 , , , cord-022526-j9kg00qf 2886 3 multiple multiple JJ cord-022526-j9kg00qf 2886 4 factors factor NNS cord-022526-j9kg00qf 2886 5 likely likely RB cord-022526-j9kg00qf 2886 6 were be VBD cord-022526-j9kg00qf 2886 7 involved involve VBN cord-022526-j9kg00qf 2886 8 in in IN cord-022526-j9kg00qf 2886 9 critically critically RB cord-022526-j9kg00qf 2886 10 ill ill JJ cord-022526-j9kg00qf 2886 11 foals foal NNS cord-022526-j9kg00qf 2886 12 of of IN cord-022526-j9kg00qf 2886 13 this this DT cord-022526-j9kg00qf 2886 14 study study NN cord-022526-j9kg00qf 2886 15 , , , cord-022526-j9kg00qf 2886 16 and and CC cord-022526-j9kg00qf 2886 17 the the DT cord-022526-j9kg00qf 2886 18 true true JJ cord-022526-j9kg00qf 2886 19 ontogeny ontogeny NN cord-022526-j9kg00qf 2886 20 of of IN cord-022526-j9kg00qf 2886 21 gastric gastric JJ cord-022526-j9kg00qf 2886 22 acid acid NN cord-022526-j9kg00qf 2886 23 production production NN cord-022526-j9kg00qf 2886 24 in in IN cord-022526-j9kg00qf 2886 25 foals foal NNS cord-022526-j9kg00qf 2886 26 is be VBZ cord-022526-j9kg00qf 2886 27 currently currently RB cord-022526-j9kg00qf 2886 28 unknown unknown JJ cord-022526-j9kg00qf 2886 29 . . . cord-022526-j9kg00qf 2887 1 Equine equine JJ cord-022526-j9kg00qf 2887 2 squamous squamous JJ cord-022526-j9kg00qf 2887 3 mucosa mucosa NN cord-022526-j9kg00qf 2887 4 is be VBZ cord-022526-j9kg00qf 2887 5 thin thin JJ cord-022526-j9kg00qf 2887 6 at at IN cord-022526-j9kg00qf 2887 7 birth birth NN cord-022526-j9kg00qf 2887 8 but but CC cord-022526-j9kg00qf 2887 9 becomes become VBZ cord-022526-j9kg00qf 2887 10 hyperplastic hyperplastic JJ cord-022526-j9kg00qf 2887 11 and and CC cord-022526-j9kg00qf 2887 12 parakeratotic parakeratotic JJ cord-022526-j9kg00qf 2887 13 within within IN cord-022526-j9kg00qf 2887 14 days day NNS cord-022526-j9kg00qf 2887 15 . . . cord-022526-j9kg00qf 2888 1 33 33 CD cord-022526-j9kg00qf 2889 1 The the DT cord-022526-j9kg00qf 2889 2 parallel parallel NN cord-022526-j9kg00qf 2889 3 between between IN cord-022526-j9kg00qf 2889 4 decreasing decrease VBG cord-022526-j9kg00qf 2889 5 pH ph NN cord-022526-j9kg00qf 2889 6 and and CC cord-022526-j9kg00qf 2889 7 proliferation proliferation NN cord-022526-j9kg00qf 2889 8 of of IN cord-022526-j9kg00qf 2889 9 squamous squamous JJ cord-022526-j9kg00qf 2889 10 epithelium epithelium NN cord-022526-j9kg00qf 2889 11 correlates correlate VBZ cord-022526-j9kg00qf 2889 12 with with IN cord-022526-j9kg00qf 2889 13 that that DT cord-022526-j9kg00qf 2889 14 observed observe VBN cord-022526-j9kg00qf 2889 15 in in IN cord-022526-j9kg00qf 2889 16 other other JJ cord-022526-j9kg00qf 2889 17 species specie NNS cord-022526-j9kg00qf 2889 18 . . . cord-022526-j9kg00qf 2890 1 34 34 CD cord-022526-j9kg00qf 2891 1 The the DT cord-022526-j9kg00qf 2891 2 combination combination NN cord-022526-j9kg00qf 2891 3 of of IN cord-022526-j9kg00qf 2891 4 a a DT cord-022526-j9kg00qf 2891 5 thin thin JJ cord-022526-j9kg00qf 2891 6 gastric gastric JJ cord-022526-j9kg00qf 2891 7 epithelium epithelium NN cord-022526-j9kg00qf 2891 8 with with IN cord-022526-j9kg00qf 2891 9 a a DT cord-022526-j9kg00qf 2891 10 high high JJ cord-022526-j9kg00qf 2891 11 acid acid NN cord-022526-j9kg00qf 2891 12 output output NN cord-022526-j9kg00qf 2891 13 may may MD cord-022526-j9kg00qf 2891 14 leave leave VB cord-022526-j9kg00qf 2891 15 neonatal neonatal JJ cord-022526-j9kg00qf 2891 16 foals foal NNS cord-022526-j9kg00qf 2891 17 susceptible susceptible JJ cord-022526-j9kg00qf 2891 18 to to IN cord-022526-j9kg00qf 2891 19 ulcer ulcer NN cord-022526-j9kg00qf 2891 20 formation formation NN cord-022526-j9kg00qf 2891 21 at at IN cord-022526-j9kg00qf 2891 22 a a DT cord-022526-j9kg00qf 2891 23 young young JJ cord-022526-j9kg00qf 2891 24 age age NN cord-022526-j9kg00qf 2891 25 . . . cord-022526-j9kg00qf 2892 1 In in IN cord-022526-j9kg00qf 2892 2 addition addition NN cord-022526-j9kg00qf 2892 3 , , , cord-022526-j9kg00qf 2892 4 one one PRP cord-022526-j9kg00qf 2892 5 must must MD cord-022526-j9kg00qf 2892 6 remember remember VB cord-022526-j9kg00qf 2892 7 the the DT cord-022526-j9kg00qf 2892 8 difference difference NN cord-022526-j9kg00qf 2892 9 in in IN cord-022526-j9kg00qf 2892 10 normal normal JJ cord-022526-j9kg00qf 2892 11 appearance appearance NN cord-022526-j9kg00qf 2892 12 of of IN cord-022526-j9kg00qf 2892 13 the the DT cord-022526-j9kg00qf 2892 14 squamous squamous JJ cord-022526-j9kg00qf 2892 15 mucosa mucosa NN cord-022526-j9kg00qf 2892 16 when when WRB cord-022526-j9kg00qf 2892 17 interpreting interpret VBG cord-022526-j9kg00qf 2892 18 gastric gastric JJ cord-022526-j9kg00qf 2892 19 endoscopy endoscopy NN cord-022526-j9kg00qf 2892 20 in in IN cord-022526-j9kg00qf 2892 21 a a DT cord-022526-j9kg00qf 2892 22 neonatal neonatal JJ cord-022526-j9kg00qf 2892 23 population population NN cord-022526-j9kg00qf 2892 24 . . . cord-022526-j9kg00qf 2893 1 In in IN cord-022526-j9kg00qf 2893 2 esophageal esophageal JJ cord-022526-j9kg00qf 2893 3 squamous squamous JJ cord-022526-j9kg00qf 2893 4 mucosa mucosa JJ cord-022526-j9kg00qf 2893 5 , , , cord-022526-j9kg00qf 2893 6 intercellular intercellular JJ cord-022526-j9kg00qf 2893 7 tight tight JJ cord-022526-j9kg00qf 2893 8 junctions junction NNS cord-022526-j9kg00qf 2893 9 and and CC cord-022526-j9kg00qf 2893 10 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2893 11 secretion secretion NN cord-022526-j9kg00qf 2893 12 are be VBP cord-022526-j9kg00qf 2893 13 the the DT cord-022526-j9kg00qf 2893 14 major major JJ cord-022526-j9kg00qf 2893 15 factors factor NNS cord-022526-j9kg00qf 2893 16 involved involve VBN cord-022526-j9kg00qf 2893 17 in in IN cord-022526-j9kg00qf 2893 18 protection protection NN cord-022526-j9kg00qf 2893 19 against against IN cord-022526-j9kg00qf 2893 20 acid acid JJ cord-022526-j9kg00qf 2893 21 injury injury NN cord-022526-j9kg00qf 2893 22 in in IN cord-022526-j9kg00qf 2893 23 other other JJ cord-022526-j9kg00qf 2893 24 species specie NNS cord-022526-j9kg00qf 2893 25 , , , cord-022526-j9kg00qf 2893 26 although although IN cord-022526-j9kg00qf 2893 27 squamous squamous JJ cord-022526-j9kg00qf 2893 28 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2893 29 secretion secretion NN cord-022526-j9kg00qf 2893 30 had have VBD cord-022526-j9kg00qf 2893 31 not not RB cord-022526-j9kg00qf 2893 32 been be VBN cord-022526-j9kg00qf 2893 33 documented document VBN cord-022526-j9kg00qf 2893 34 in in IN cord-022526-j9kg00qf 2893 35 the the DT cord-022526-j9kg00qf 2893 36 horse horse NN cord-022526-j9kg00qf 2893 37 . . . cord-022526-j9kg00qf 2894 1 [ [ -LRB- cord-022526-j9kg00qf 2894 2 35 35 CD cord-022526-j9kg00qf 2894 3 ] ] -RRB- cord-022526-j9kg00qf 2894 4 [ [ -LRB- cord-022526-j9kg00qf 2894 5 36 36 CD cord-022526-j9kg00qf 2894 6 ] ] -RRB- cord-022526-j9kg00qf 2895 1 [ [ -LRB- cord-022526-j9kg00qf 2895 2 37 37 CD cord-022526-j9kg00qf 2895 3 ] ] -RRB- cord-022526-j9kg00qf 2896 1 The the DT cord-022526-j9kg00qf 2896 2 principal principal JJ cord-022526-j9kg00qf 2896 3 barrier barrier NN cord-022526-j9kg00qf 2896 4 is be VBZ cord-022526-j9kg00qf 2896 5 a a DT cord-022526-j9kg00qf 2896 6 glycoconjugate glycoconjugate NN cord-022526-j9kg00qf 2896 7 substance substance NN cord-022526-j9kg00qf 2896 8 secreted secrete VBN cord-022526-j9kg00qf 2896 9 by by IN cord-022526-j9kg00qf 2896 10 cells cell NNS cord-022526-j9kg00qf 2896 11 in in IN cord-022526-j9kg00qf 2896 12 the the DT cord-022526-j9kg00qf 2896 13 stratum stratum NN cord-022526-j9kg00qf 2896 14 spinosum spinosum NN cord-022526-j9kg00qf 2896 15 , , , cord-022526-j9kg00qf 2896 16 with with IN cord-022526-j9kg00qf 2896 17 a a DT cord-022526-j9kg00qf 2896 18 contribution contribution NN cord-022526-j9kg00qf 2896 19 from from IN cord-022526-j9kg00qf 2896 20 the the DT cord-022526-j9kg00qf 2896 21 tight tight JJ cord-022526-j9kg00qf 2896 22 junctions junction NNS cord-022526-j9kg00qf 2896 23 in in IN cord-022526-j9kg00qf 2896 24 the the DT cord-022526-j9kg00qf 2896 25 stratum stratum NN cord-022526-j9kg00qf 2896 26 corneum corneum NN cord-022526-j9kg00qf 2896 27 . . . cord-022526-j9kg00qf 2897 1 37 37 CD cord-022526-j9kg00qf 2898 1 This this DT cord-022526-j9kg00qf 2898 2 barrier barrier NN cord-022526-j9kg00qf 2898 3 function function NN cord-022526-j9kg00qf 2898 4 is be VBZ cord-022526-j9kg00qf 2898 5 considered consider VBN cord-022526-j9kg00qf 2898 6 weak weak JJ cord-022526-j9kg00qf 2898 7 at at IN cord-022526-j9kg00qf 2898 8 best good JJS cord-022526-j9kg00qf 2898 9 , , , cord-022526-j9kg00qf 2898 10 and and CC cord-022526-j9kg00qf 2898 11 thus thus RB cord-022526-j9kg00qf 2898 12 a a DT cord-022526-j9kg00qf 2898 13 functioning function VBG cord-022526-j9kg00qf 2898 14 lower low JJR cord-022526-j9kg00qf 2898 15 esophageal esophageal JJ cord-022526-j9kg00qf 2898 16 sphincter sphincter NN cord-022526-j9kg00qf 2898 17 , , , cord-022526-j9kg00qf 2898 18 normal normal JJ cord-022526-j9kg00qf 2898 19 salivary salivary NN cord-022526-j9kg00qf 2898 20 flow flow NN cord-022526-j9kg00qf 2898 21 , , , cord-022526-j9kg00qf 2898 22 and and CC cord-022526-j9kg00qf 2898 23 salivary salivary NN cord-022526-j9kg00qf 2898 24 mucins mucin NNS cord-022526-j9kg00qf 2898 25 contribute contribute VBP cord-022526-j9kg00qf 2898 26 to to IN cord-022526-j9kg00qf 2898 27 the the DT cord-022526-j9kg00qf 2898 28 prevention prevention NN cord-022526-j9kg00qf 2898 29 of of IN cord-022526-j9kg00qf 2898 30 acid acid JJ cord-022526-j9kg00qf 2898 31 injury injury NN cord-022526-j9kg00qf 2898 32 in in IN cord-022526-j9kg00qf 2898 33 human human JJ cord-022526-j9kg00qf 2898 34 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2898 35 reflux reflux NN cord-022526-j9kg00qf 2898 36 disease disease NN cord-022526-j9kg00qf 2898 37 . . . cord-022526-j9kg00qf 2899 1 In in IN cord-022526-j9kg00qf 2899 2 horses horse NNS cord-022526-j9kg00qf 2899 3 a a DT cord-022526-j9kg00qf 2899 4 mechanical mechanical JJ cord-022526-j9kg00qf 2899 5 barrier barrier NN cord-022526-j9kg00qf 2899 6 like like IN cord-022526-j9kg00qf 2899 7 the the DT cord-022526-j9kg00qf 2899 8 lower low JJR cord-022526-j9kg00qf 2899 9 esophageal esophageal JJ cord-022526-j9kg00qf 2899 10 sphincter sphincter NN cord-022526-j9kg00qf 2899 11 is be VBZ cord-022526-j9kg00qf 2899 12 not not RB cord-022526-j9kg00qf 2899 13 available available JJ cord-022526-j9kg00qf 2899 14 to to TO cord-022526-j9kg00qf 2899 15 protect protect VB cord-022526-j9kg00qf 2899 16 the the DT cord-022526-j9kg00qf 2899 17 gastric gastric JJ cord-022526-j9kg00qf 2899 18 squamous squamous JJ cord-022526-j9kg00qf 2899 19 mucosa mucosa NN cord-022526-j9kg00qf 2899 20 from from IN cord-022526-j9kg00qf 2899 21 acid acid JJ cord-022526-j9kg00qf 2899 22 exposure exposure NN cord-022526-j9kg00qf 2899 23 . . . cord-022526-j9kg00qf 2900 1 The the DT cord-022526-j9kg00qf 2900 2 normal normal JJ cord-022526-j9kg00qf 2900 3 gastric gastric JJ cord-022526-j9kg00qf 2900 4 fill fill NN cord-022526-j9kg00qf 2900 5 line line NN cord-022526-j9kg00qf 2900 6 rests rest VBZ cord-022526-j9kg00qf 2900 7 just just RB cord-022526-j9kg00qf 2900 8 below below IN cord-022526-j9kg00qf 2900 9 the the DT cord-022526-j9kg00qf 2900 10 cardia cardia NN cord-022526-j9kg00qf 2900 11 , , , cord-022526-j9kg00qf 2900 12 so so RB cord-022526-j9kg00qf 2901 1 only only RB cord-022526-j9kg00qf 2901 2 the the DT cord-022526-j9kg00qf 2901 3 squamous squamous JJ cord-022526-j9kg00qf 2901 4 mucosa mucosa NN cord-022526-j9kg00qf 2901 5 along along IN cord-022526-j9kg00qf 2901 6 the the DT cord-022526-j9kg00qf 2901 7 lesser less JJR cord-022526-j9kg00qf 2901 8 curvature curvature NN cord-022526-j9kg00qf 2901 9 adjacent adjacent JJ cord-022526-j9kg00qf 2901 10 to to IN cord-022526-j9kg00qf 2901 11 the the DT cord-022526-j9kg00qf 2901 12 margo margo NNP cord-022526-j9kg00qf 2901 13 plicatus plicatus NNP cord-022526-j9kg00qf 2901 14 should should MD cord-022526-j9kg00qf 2901 15 receive receive VB cord-022526-j9kg00qf 2901 16 exposure exposure NN cord-022526-j9kg00qf 2901 17 to to IN cord-022526-j9kg00qf 2901 18 acidic acidic JJ cord-022526-j9kg00qf 2901 19 gastric gastric JJ cord-022526-j9kg00qf 2901 20 contents content NNS cord-022526-j9kg00qf 2901 21 regularly regularly RB cord-022526-j9kg00qf 2901 22 . . . cord-022526-j9kg00qf 2902 1 Not not RB cord-022526-j9kg00qf 2902 2 surprisingly surprisingly RB cord-022526-j9kg00qf 2902 3 , , , cord-022526-j9kg00qf 2902 4 this this DT cord-022526-j9kg00qf 2902 5 correlates correlate VBZ cord-022526-j9kg00qf 2902 6 with with IN cord-022526-j9kg00qf 2902 7 the the DT cord-022526-j9kg00qf 2902 8 most most RBS cord-022526-j9kg00qf 2902 9 common common JJ cord-022526-j9kg00qf 2902 10 location location NN cord-022526-j9kg00qf 2902 11 of of IN cord-022526-j9kg00qf 2902 12 squamous squamous JJ cord-022526-j9kg00qf 2902 13 mucosal mucosal JJ cord-022526-j9kg00qf 2902 14 ulceration ulceration NN cord-022526-j9kg00qf 2902 15 . . . cord-022526-j9kg00qf 2903 1 Bile bile NN cord-022526-j9kg00qf 2903 2 salts salt NNS cord-022526-j9kg00qf 2903 3 and and CC cord-022526-j9kg00qf 2903 4 pepsin pepsin NN cord-022526-j9kg00qf 2903 5 have have VBP cord-022526-j9kg00qf 2903 6 been be VBN cord-022526-j9kg00qf 2903 7 implicated implicate VBN cord-022526-j9kg00qf 2903 8 as as IN cord-022526-j9kg00qf 2903 9 contributing contribute VBG cord-022526-j9kg00qf 2903 10 factors factor NNS cord-022526-j9kg00qf 2903 11 to to IN cord-022526-j9kg00qf 2903 12 ulcer ulcer VB cord-022526-j9kg00qf 2903 13 disease disease NN cord-022526-j9kg00qf 2903 14 in in IN cord-022526-j9kg00qf 2903 15 many many JJ cord-022526-j9kg00qf 2903 16 species specie NNS cord-022526-j9kg00qf 2903 17 . . . cord-022526-j9kg00qf 2904 1 In in IN cord-022526-j9kg00qf 2904 2 rabbit rabbit NN cord-022526-j9kg00qf 2904 3 esophageal esophageal JJ cord-022526-j9kg00qf 2904 4 mucosa mucosa NN cord-022526-j9kg00qf 2904 5 , , , cord-022526-j9kg00qf 2904 6 bile bile NN cord-022526-j9kg00qf 2904 7 salt salt NN cord-022526-j9kg00qf 2904 8 absorption absorption NN cord-022526-j9kg00qf 2904 9 occurs occur VBZ cord-022526-j9kg00qf 2904 10 and and CC cord-022526-j9kg00qf 2904 11 is be VBZ cord-022526-j9kg00qf 2904 12 correlated correlate VBN cord-022526-j9kg00qf 2904 13 directly directly RB cord-022526-j9kg00qf 2904 14 with with IN cord-022526-j9kg00qf 2904 15 mucosal mucosal JJ cord-022526-j9kg00qf 2904 16 barrier barrier NN cord-022526-j9kg00qf 2904 17 disruption disruption NN cord-022526-j9kg00qf 2904 18 . . . cord-022526-j9kg00qf 2905 1 The the DT cord-022526-j9kg00qf 2905 2 unconjugated unconjugated JJ cord-022526-j9kg00qf 2905 3 bile bile NN cord-022526-j9kg00qf 2905 4 salts salt NNS cord-022526-j9kg00qf 2905 5 cholate cholate NN cord-022526-j9kg00qf 2905 6 and and CC cord-022526-j9kg00qf 2905 7 deoxycholate deoxycholate NNP cord-022526-j9kg00qf 2905 8 have have VBP cord-022526-j9kg00qf 2905 9 a a DT cord-022526-j9kg00qf 2905 10 pK pK NNP cord-022526-j9kg00qf 2905 11 a a DT cord-022526-j9kg00qf 2905 12 ( ( -LRB- cord-022526-j9kg00qf 2905 13 negative negative JJ cord-022526-j9kg00qf 2905 14 logarithm logarithm NN cord-022526-j9kg00qf 2905 15 of of IN cord-022526-j9kg00qf 2905 16 the the DT cord-022526-j9kg00qf 2905 17 ionization ionization NN cord-022526-j9kg00qf 2905 18 constant constant JJ cord-022526-j9kg00qf 2905 19 of of IN cord-022526-j9kg00qf 2905 20 an an DT cord-022526-j9kg00qf 2905 21 acid acid NN cord-022526-j9kg00qf 2905 22 ) ) -RRB- cord-022526-j9kg00qf 2905 23 of of IN cord-022526-j9kg00qf 2905 24 5 5 CD cord-022526-j9kg00qf 2905 25 and and CC cord-022526-j9kg00qf 2905 26 5.3 5.3 CD cord-022526-j9kg00qf 2905 27 , , , cord-022526-j9kg00qf 2905 28 respectively respectively RB cord-022526-j9kg00qf 2905 29 , , , cord-022526-j9kg00qf 2905 30 and and CC cord-022526-j9kg00qf 2905 31 therefore therefore RB cord-022526-j9kg00qf 2905 32 can can MD cord-022526-j9kg00qf 2905 33 not not RB cord-022526-j9kg00qf 2905 34 remain remain VB cord-022526-j9kg00qf 2905 35 in in IN cord-022526-j9kg00qf 2905 36 solution solution NN cord-022526-j9kg00qf 2905 37 and and CC cord-022526-j9kg00qf 2905 38 cause cause VB cord-022526-j9kg00qf 2905 39 mucosal mucosal JJ cord-022526-j9kg00qf 2905 40 damage damage NN cord-022526-j9kg00qf 2905 41 in in IN cord-022526-j9kg00qf 2905 42 the the DT cord-022526-j9kg00qf 2905 43 presence presence NN cord-022526-j9kg00qf 2905 44 of of IN cord-022526-j9kg00qf 2905 45 acid acid NN cord-022526-j9kg00qf 2905 46 . . . cord-022526-j9kg00qf 2906 1 Alternatively alternatively RB cord-022526-j9kg00qf 2906 2 , , , cord-022526-j9kg00qf 2906 3 the the DT cord-022526-j9kg00qf 2906 4 conjugated conjugated JJ cord-022526-j9kg00qf 2906 5 bile bile NN cord-022526-j9kg00qf 2906 6 salt salt NN cord-022526-j9kg00qf 2906 7 taurocholate taurocholate NN cord-022526-j9kg00qf 2906 8 ( ( -LRB- cord-022526-j9kg00qf 2906 9 pK pK NNP cord-022526-j9kg00qf 2906 10 a a DT cord-022526-j9kg00qf 2906 11 1.9 1.9 CD cord-022526-j9kg00qf 2906 12 ) ) -RRB- cord-022526-j9kg00qf 2906 13 can can MD cord-022526-j9kg00qf 2906 14 cause cause VB cord-022526-j9kg00qf 2906 15 mucosal mucosal JJ cord-022526-j9kg00qf 2906 16 injury injury NN cord-022526-j9kg00qf 2906 17 in in IN cord-022526-j9kg00qf 2906 18 the the DT cord-022526-j9kg00qf 2906 19 ionized ionized JJ cord-022526-j9kg00qf 2906 20 salt salt NN cord-022526-j9kg00qf 2906 21 form form NN cord-022526-j9kg00qf 2906 22 at at IN cord-022526-j9kg00qf 2906 23 pH pH NNP cord-022526-j9kg00qf 2906 24 7 7 CD cord-022526-j9kg00qf 2906 25 or or CC cord-022526-j9kg00qf 2906 26 the the DT cord-022526-j9kg00qf 2906 27 un un NNP cord-022526-j9kg00qf 2906 28 - - JJ cord-022526-j9kg00qf 2906 29 ionized ionize VBN cord-022526-j9kg00qf 2906 30 acid acid NN cord-022526-j9kg00qf 2906 31 form form NN cord-022526-j9kg00qf 2906 32 at at IN cord-022526-j9kg00qf 2906 33 pH ph NN cord-022526-j9kg00qf 2906 34 1 1 CD cord-022526-j9kg00qf 2906 35 to to IN cord-022526-j9kg00qf 2906 36 2 2 CD cord-022526-j9kg00qf 2906 37 . . . cord-022526-j9kg00qf 2907 1 38 38 CD cord-022526-j9kg00qf 2908 1 In in IN cord-022526-j9kg00qf 2908 2 the the DT cord-022526-j9kg00qf 2908 3 pig pig NN cord-022526-j9kg00qf 2908 4 , , , cord-022526-j9kg00qf 2908 5 bile bile NN cord-022526-j9kg00qf 2908 6 salts salt NNS cord-022526-j9kg00qf 2908 7 or or CC cord-022526-j9kg00qf 2908 8 acid acid NN cord-022526-j9kg00qf 2908 9 alone alone RB cord-022526-j9kg00qf 2908 10 cause cause VBP cord-022526-j9kg00qf 2908 11 squamous squamous JJ cord-022526-j9kg00qf 2908 12 mucosal mucosal JJ cord-022526-j9kg00qf 2908 13 damage damage NN cord-022526-j9kg00qf 2908 14 , , , cord-022526-j9kg00qf 2908 15 whereas whereas IN cord-022526-j9kg00qf 2908 16 a a DT cord-022526-j9kg00qf 2908 17 combination combination NN cord-022526-j9kg00qf 2908 18 of of IN cord-022526-j9kg00qf 2908 19 the the DT cord-022526-j9kg00qf 2908 20 two two CD cord-022526-j9kg00qf 2908 21 result result NN cord-022526-j9kg00qf 2908 22 in in IN cord-022526-j9kg00qf 2908 23 extensive extensive JJ cord-022526-j9kg00qf 2908 24 damage damage NN cord-022526-j9kg00qf 2908 25 in in IN cord-022526-j9kg00qf 2908 26 vitro vitro FW cord-022526-j9kg00qf 2908 27 . . . cord-022526-j9kg00qf 2909 1 39 39 CD cord-022526-j9kg00qf 2910 1 In in IN cord-022526-j9kg00qf 2910 2 the the DT cord-022526-j9kg00qf 2910 3 horse horse NN cord-022526-j9kg00qf 2910 4 a a DT cord-022526-j9kg00qf 2910 5 similar similar JJ cord-022526-j9kg00qf 2910 6 synergistically synergistically RB cord-022526-j9kg00qf 2910 7 damaging damaging JJ cord-022526-j9kg00qf 2910 8 effect effect NN cord-022526-j9kg00qf 2910 9 was be VBD cord-022526-j9kg00qf 2910 10 found find VBN cord-022526-j9kg00qf 2910 11 with with IN cord-022526-j9kg00qf 2910 12 the the DT cord-022526-j9kg00qf 2910 13 addition addition NN cord-022526-j9kg00qf 2910 14 of of IN cord-022526-j9kg00qf 2910 15 bile bile NN cord-022526-j9kg00qf 2910 16 salts salt NNS cord-022526-j9kg00qf 2910 17 and and CC cord-022526-j9kg00qf 2910 18 acid acid NN cord-022526-j9kg00qf 2910 19 ( ( -LRB- cord-022526-j9kg00qf 2910 20 pH pH NNP cord-022526-j9kg00qf 2910 21 2.5 2.5 CD cord-022526-j9kg00qf 2910 22 ) ) -RRB- cord-022526-j9kg00qf 2910 23 to to IN cord-022526-j9kg00qf 2910 24 stratified stratified JJ cord-022526-j9kg00qf 2910 25 squamous squamous JJ cord-022526-j9kg00qf 2910 26 mucosa mucosa NN cord-022526-j9kg00qf 2910 27 in in IN cord-022526-j9kg00qf 2910 28 vitro vitro FW cord-022526-j9kg00qf 2910 29 in in IN cord-022526-j9kg00qf 2910 30 one one CD cord-022526-j9kg00qf 2910 31 study study NN cord-022526-j9kg00qf 2910 32 . . . cord-022526-j9kg00qf 2911 1 40 40 CD cord-022526-j9kg00qf 2912 1 In in IN cord-022526-j9kg00qf 2912 2 addition addition NN cord-022526-j9kg00qf 2912 3 , , , cord-022526-j9kg00qf 2912 4 the the DT cord-022526-j9kg00qf 2912 5 investigators investigator NNS cord-022526-j9kg00qf 2912 6 were be VBD cord-022526-j9kg00qf 2912 7 able able JJ cord-022526-j9kg00qf 2912 8 to to TO cord-022526-j9kg00qf 2912 9 document document VB cord-022526-j9kg00qf 2912 10 levels level NNS cord-022526-j9kg00qf 2912 11 of of IN cord-022526-j9kg00qf 2912 12 bile bile NN cord-022526-j9kg00qf 2912 13 salts salt NNS cord-022526-j9kg00qf 2912 14 and and CC cord-022526-j9kg00qf 2912 15 acid acid NN cord-022526-j9kg00qf 2912 16 sufficient sufficient JJ cord-022526-j9kg00qf 2912 17 to to TO cord-022526-j9kg00qf 2912 18 cause cause VB cord-022526-j9kg00qf 2912 19 mucosal mucosal JJ cord-022526-j9kg00qf 2912 20 damage damage NN cord-022526-j9kg00qf 2912 21 in in IN cord-022526-j9kg00qf 2912 22 gastric gastric JJ cord-022526-j9kg00qf 2912 23 contents content NNS cord-022526-j9kg00qf 2912 24 within within IN cord-022526-j9kg00qf 2912 25 14 14 CD cord-022526-j9kg00qf 2912 26 hours hour NNS cord-022526-j9kg00qf 2912 27 of of IN cord-022526-j9kg00qf 2912 28 feed feed NN cord-022526-j9kg00qf 2912 29 deprivation deprivation NN cord-022526-j9kg00qf 2912 30 . . . cord-022526-j9kg00qf 2913 1 This this DT cord-022526-j9kg00qf 2913 2 is be VBZ cord-022526-j9kg00qf 2913 3 not not RB cord-022526-j9kg00qf 2913 4 surprising surprising JJ cord-022526-j9kg00qf 2913 5 , , , cord-022526-j9kg00qf 2913 6 given give VBN cord-022526-j9kg00qf 2913 7 that that IN cord-022526-j9kg00qf 2913 8 duodenogastric duodenogastric JJ cord-022526-j9kg00qf 2913 9 reflux reflux NN cord-022526-j9kg00qf 2913 10 occurs occur VBZ cord-022526-j9kg00qf 2913 11 normally normally RB cord-022526-j9kg00qf 2913 12 in in IN cord-022526-j9kg00qf 2913 13 the the DT cord-022526-j9kg00qf 2913 14 horse horse NN cord-022526-j9kg00qf 2913 15 . . . cord-022526-j9kg00qf 2914 1 41 41 CD cord-022526-j9kg00qf 2915 1 In in IN cord-022526-j9kg00qf 2915 2 a a DT cord-022526-j9kg00qf 2915 3 separate separate JJ cord-022526-j9kg00qf 2915 4 in in IN cord-022526-j9kg00qf 2915 5 vitro vitro FW cord-022526-j9kg00qf 2915 6 study study NN cord-022526-j9kg00qf 2915 7 of of IN cord-022526-j9kg00qf 2915 8 equine equine JJ cord-022526-j9kg00qf 2915 9 squamous squamous JJ cord-022526-j9kg00qf 2915 10 mucosa mucosa NN cord-022526-j9kg00qf 2915 11 , , , cord-022526-j9kg00qf 2915 12 prolonged prolong VBN cord-022526-j9kg00qf 2915 13 exposure exposure NN cord-022526-j9kg00qf 2915 14 to to IN cord-022526-j9kg00qf 2915 15 acid acid NN cord-022526-j9kg00qf 2915 16 alone alone RB cord-022526-j9kg00qf 2916 1 ( ( -LRB- cord-022526-j9kg00qf 2916 2 pH pH NNP cord-022526-j9kg00qf 2916 3 1.5 1.5 CD cord-022526-j9kg00qf 2916 4 ) ) -RRB- cord-022526-j9kg00qf 2916 5 had have VBD cord-022526-j9kg00qf 2916 6 a a DT cord-022526-j9kg00qf 2916 7 damaging damaging JJ cord-022526-j9kg00qf 2916 8 effect effect NN cord-022526-j9kg00qf 2916 9 , , , cord-022526-j9kg00qf 2916 10 and and CC cord-022526-j9kg00qf 2916 11 synergism synergism NN cord-022526-j9kg00qf 2916 12 with with IN cord-022526-j9kg00qf 2916 13 exposure exposure NN cord-022526-j9kg00qf 2916 14 to to IN cord-022526-j9kg00qf 2916 15 a a DT cord-022526-j9kg00qf 2916 16 combination combination NN cord-022526-j9kg00qf 2916 17 of of IN cord-022526-j9kg00qf 2916 18 acid acid NN cord-022526-j9kg00qf 2916 19 and and CC cord-022526-j9kg00qf 2916 20 pepsin pepsin NN cord-022526-j9kg00qf 2916 21 or or CC cord-022526-j9kg00qf 2916 22 taurocholate taurocholate NNP cord-022526-j9kg00qf 2916 23 was be VBD cord-022526-j9kg00qf 2916 24 not not RB cord-022526-j9kg00qf 2916 25 found find VBN cord-022526-j9kg00qf 2916 26 . . . cord-022526-j9kg00qf 2917 1 42 42 CD cord-022526-j9kg00qf 2918 1 The the DT cord-022526-j9kg00qf 2918 2 lack lack NN cord-022526-j9kg00qf 2918 3 of of IN cord-022526-j9kg00qf 2918 4 synergism synergism NN cord-022526-j9kg00qf 2918 5 likely likely RB cord-022526-j9kg00qf 2918 6 is be VBZ cord-022526-j9kg00qf 2918 7 caused cause VBN cord-022526-j9kg00qf 2918 8 by by IN cord-022526-j9kg00qf 2918 9 the the DT cord-022526-j9kg00qf 2918 10 lower low JJR cord-022526-j9kg00qf 2918 11 pH pH NNP cord-022526-j9kg00qf 2918 12 used use VBN cord-022526-j9kg00qf 2918 13 in in IN cord-022526-j9kg00qf 2918 14 this this DT cord-022526-j9kg00qf 2918 15 study study NN cord-022526-j9kg00qf 2918 16 and and CC cord-022526-j9kg00qf 2918 17 stresses stress VBZ cord-022526-j9kg00qf 2918 18 the the DT cord-022526-j9kg00qf 2918 19 importance importance NN cord-022526-j9kg00qf 2918 20 of of IN cord-022526-j9kg00qf 2918 21 acid acid JJ cord-022526-j9kg00qf 2918 22 exposure exposure NN cord-022526-j9kg00qf 2918 23 in in IN cord-022526-j9kg00qf 2918 24 squamous squamous JJ cord-022526-j9kg00qf 2918 25 ulcer ulcer NN cord-022526-j9kg00qf 2918 26 disease disease NN cord-022526-j9kg00qf 2918 27 . . . cord-022526-j9kg00qf 2919 1 Pepsinogens pepsinogen NNS cord-022526-j9kg00qf 2919 2 are be VBP cord-022526-j9kg00qf 2919 3 secreted secrete VBN cord-022526-j9kg00qf 2919 4 primarily primarily RB cord-022526-j9kg00qf 2919 5 by by IN cord-022526-j9kg00qf 2919 6 chief chief JJ cord-022526-j9kg00qf 2919 7 cells cell NNS cord-022526-j9kg00qf 2919 8 , , , cord-022526-j9kg00qf 2919 9 although although IN cord-022526-j9kg00qf 2919 10 secretion secretion NN cord-022526-j9kg00qf 2919 11 by by IN cord-022526-j9kg00qf 2919 12 neck neck NN cord-022526-j9kg00qf 2919 13 cells cell NNS cord-022526-j9kg00qf 2919 14 , , , cord-022526-j9kg00qf 2919 15 cardiac cardiac JJ cord-022526-j9kg00qf 2919 16 glands gland NNS cord-022526-j9kg00qf 2919 17 , , , cord-022526-j9kg00qf 2919 18 and and CC cord-022526-j9kg00qf 2919 19 antral antral JJ cord-022526-j9kg00qf 2919 20 pyloric pyloric JJ cord-022526-j9kg00qf 2919 21 glands gland NNS cord-022526-j9kg00qf 2919 22 also also RB cord-022526-j9kg00qf 2919 23 occurs occur VBZ cord-022526-j9kg00qf 2919 24 . . . cord-022526-j9kg00qf 2920 1 43 43 CD cord-022526-j9kg00qf 2921 1 In in IN cord-022526-j9kg00qf 2921 2 an an DT cord-022526-j9kg00qf 2921 3 acidic acidic JJ cord-022526-j9kg00qf 2921 4 environment environment NN cord-022526-j9kg00qf 2921 5 ( ( -LRB- cord-022526-j9kg00qf 2921 6 pH ph XX cord-022526-j9kg00qf 2921 7 < < XX cord-022526-j9kg00qf 2921 8 3.0 3.0 CD cord-022526-j9kg00qf 2921 9 ) ) -RRB- cord-022526-j9kg00qf 2921 10 , , , cord-022526-j9kg00qf 2921 11 pepsinogen pepsinogen NNP cord-022526-j9kg00qf 2921 12 is be VBZ cord-022526-j9kg00qf 2921 13 converted convert VBN cord-022526-j9kg00qf 2921 14 to to IN cord-022526-j9kg00qf 2921 15 the the DT cord-022526-j9kg00qf 2921 16 active active JJ cord-022526-j9kg00qf 2921 17 pepsin pepsin NN cord-022526-j9kg00qf 2921 18 . . . cord-022526-j9kg00qf 2922 1 Although although IN cord-022526-j9kg00qf 2922 2 the the DT cord-022526-j9kg00qf 2922 3 proteolytic proteolytic JJ cord-022526-j9kg00qf 2922 4 activity activity NN cord-022526-j9kg00qf 2922 5 of of IN cord-022526-j9kg00qf 2922 6 pepsin pepsin NN cord-022526-j9kg00qf 2922 7 normally normally RB cord-022526-j9kg00qf 2922 8 is be VBZ cord-022526-j9kg00qf 2922 9 directed direct VBN cord-022526-j9kg00qf 2922 10 toward toward IN cord-022526-j9kg00qf 2922 11 dietary dietary JJ cord-022526-j9kg00qf 2922 12 protein protein NN cord-022526-j9kg00qf 2922 13 , , , cord-022526-j9kg00qf 2922 14 it -PRON- PRP cord-022526-j9kg00qf 2922 15 also also RB cord-022526-j9kg00qf 2922 16 can can MD cord-022526-j9kg00qf 2922 17 act act VB cord-022526-j9kg00qf 2922 18 on on IN cord-022526-j9kg00qf 2922 19 the the DT cord-022526-j9kg00qf 2922 20 gastric gastric JJ cord-022526-j9kg00qf 2922 21 mucosa mucosa NN cord-022526-j9kg00qf 2922 22 . . . cord-022526-j9kg00qf 2923 1 44 44 CD cord-022526-j9kg00qf 2924 1 Thus thus RB cord-022526-j9kg00qf 2924 2 acid acid NN cord-022526-j9kg00qf 2924 3 remains remain VBZ cord-022526-j9kg00qf 2924 4 the the DT cord-022526-j9kg00qf 2924 5 major major JJ cord-022526-j9kg00qf 2924 6 contributing contributing NN cord-022526-j9kg00qf 2924 7 factor factor NN cord-022526-j9kg00qf 2924 8 to to IN cord-022526-j9kg00qf 2924 9 squamous squamous JJ cord-022526-j9kg00qf 2924 10 mucosal mucosal JJ cord-022526-j9kg00qf 2924 11 damage damage NN cord-022526-j9kg00qf 2924 12 , , , cord-022526-j9kg00qf 2924 13 although although IN cord-022526-j9kg00qf 2924 14 other other JJ cord-022526-j9kg00qf 2924 15 factors factor NNS cord-022526-j9kg00qf 2924 16 such such JJ cord-022526-j9kg00qf 2924 17 as as IN cord-022526-j9kg00qf 2924 18 pepsin pepsin NN cord-022526-j9kg00qf 2924 19 and and CC cord-022526-j9kg00qf 2924 20 bile bile NN cord-022526-j9kg00qf 2924 21 salts salt NNS cord-022526-j9kg00qf 2924 22 may may MD cord-022526-j9kg00qf 2924 23 play play VB cord-022526-j9kg00qf 2924 24 an an DT cord-022526-j9kg00qf 2924 25 important important JJ cord-022526-j9kg00qf 2924 26 role role NN cord-022526-j9kg00qf 2924 27 as as RB cord-022526-j9kg00qf 2924 28 well well RB cord-022526-j9kg00qf 2924 29 in in IN cord-022526-j9kg00qf 2924 30 the the DT cord-022526-j9kg00qf 2924 31 initiation initiation NN cord-022526-j9kg00qf 2924 32 or or CC cord-022526-j9kg00qf 2924 33 perpetuation perpetuation NN cord-022526-j9kg00qf 2924 34 of of IN cord-022526-j9kg00qf 2924 35 disease disease NN cord-022526-j9kg00qf 2924 36 . . . cord-022526-j9kg00qf 2925 1 Several several JJ cord-022526-j9kg00qf 2925 2 mechanisms mechanism NNS cord-022526-j9kg00qf 2925 3 help help VBP cord-022526-j9kg00qf 2925 4 protect protect VB cord-022526-j9kg00qf 2925 5 the the DT cord-022526-j9kg00qf 2925 6 glandular glandular JJ cord-022526-j9kg00qf 2925 7 mucosa mucosa NN cord-022526-j9kg00qf 2925 8 from from IN cord-022526-j9kg00qf 2925 9 acid acid JJ cord-022526-j9kg00qf 2925 10 injury injury NN cord-022526-j9kg00qf 2925 11 . . . cord-022526-j9kg00qf 2926 1 The the DT cord-022526-j9kg00qf 2926 2 mucus mucus NN cord-022526-j9kg00qf 2926 3 - - HYPH cord-022526-j9kg00qf 2926 4 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2926 5 layer layer NN cord-022526-j9kg00qf 2926 6 serves serve VBZ cord-022526-j9kg00qf 2926 7 to to TO cord-022526-j9kg00qf 2926 8 titrate titrate VB cord-022526-j9kg00qf 2926 9 H h NN cord-022526-j9kg00qf 2926 10 + + CC cord-022526-j9kg00qf 2927 1 ion ion NN cord-022526-j9kg00qf 2927 2 from from IN cord-022526-j9kg00qf 2927 3 the the DT cord-022526-j9kg00qf 2927 4 gastric gastric JJ cord-022526-j9kg00qf 2927 5 lumen lumen NN cord-022526-j9kg00qf 2927 6 to to IN cord-022526-j9kg00qf 2927 7 CO CO NNP cord-022526-j9kg00qf 2927 8 2 2 CD cord-022526-j9kg00qf 2927 9 and and CC cord-022526-j9kg00qf 2927 10 H H NNP cord-022526-j9kg00qf 2927 11 2 2 CD cord-022526-j9kg00qf 2927 12 O. O. NNP cord-022526-j9kg00qf 2927 13 Cellular Cellular NNP cord-022526-j9kg00qf 2927 14 restitution restitution NN cord-022526-j9kg00qf 2927 15 and and CC cord-022526-j9kg00qf 2927 16 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 2927 17 of of IN cord-022526-j9kg00qf 2927 18 the the DT cord-022526-j9kg00qf 2927 19 E E NNP cord-022526-j9kg00qf 2927 20 series series NN cord-022526-j9kg00qf 2927 21 , , , cord-022526-j9kg00qf 2927 22 which which WDT cord-022526-j9kg00qf 2927 23 enhance enhance VBP cord-022526-j9kg00qf 2927 24 mucosal mucosal JJ cord-022526-j9kg00qf 2927 25 blood blood NN cord-022526-j9kg00qf 2927 26 flow flow NN cord-022526-j9kg00qf 2927 27 and and CC cord-022526-j9kg00qf 2927 28 secretion secretion NN cord-022526-j9kg00qf 2927 29 of of IN cord-022526-j9kg00qf 2927 30 mucus mucus NN cord-022526-j9kg00qf 2927 31 and and CC cord-022526-j9kg00qf 2927 32 bicarbonate bicarbonate NN cord-022526-j9kg00qf 2927 33 in in IN cord-022526-j9kg00qf 2927 34 the the DT cord-022526-j9kg00qf 2927 35 glandular glandular JJ cord-022526-j9kg00qf 2927 36 mucosa mucosa NN cord-022526-j9kg00qf 2927 37 have have VBP cord-022526-j9kg00qf 2927 38 not not RB cord-022526-j9kg00qf 2927 39 been be VBN cord-022526-j9kg00qf 2927 40 documented document VBN cord-022526-j9kg00qf 2927 41 in in IN cord-022526-j9kg00qf 2927 42 squamous squamous JJ cord-022526-j9kg00qf 2927 43 epithelium epithelium NN cord-022526-j9kg00qf 2927 44 . . . cord-022526-j9kg00qf 2928 1 21 21 CD cord-022526-j9kg00qf 2928 2 , , , cord-022526-j9kg00qf 2928 3 36 36 CD cord-022526-j9kg00qf 2928 4 Of of IN cord-022526-j9kg00qf 2928 5 these these DT cord-022526-j9kg00qf 2928 6 mechanisms mechanism NNS cord-022526-j9kg00qf 2928 7 , , , cord-022526-j9kg00qf 2928 8 mucosal mucosal JJ cord-022526-j9kg00qf 2928 9 blood blood NN cord-022526-j9kg00qf 2928 10 flow flow NN cord-022526-j9kg00qf 2928 11 is be VBZ cord-022526-j9kg00qf 2928 12 likely likely RB cord-022526-j9kg00qf 2928 13 the the DT cord-022526-j9kg00qf 2928 14 most most RBS cord-022526-j9kg00qf 2928 15 important important JJ cord-022526-j9kg00qf 2928 16 contributor contributor NN cord-022526-j9kg00qf 2928 17 to to IN cord-022526-j9kg00qf 2928 18 overall overall RB cord-022526-j9kg00qf 2928 19 gastric gastric JJ cord-022526-j9kg00qf 2928 20 mucosal mucosal JJ cord-022526-j9kg00qf 2928 21 health health NN cord-022526-j9kg00qf 2928 22 . . . cord-022526-j9kg00qf 2929 1 Nitric nitric NN cord-022526-j9kg00qf 2929 2 oxide oxide NN cord-022526-j9kg00qf 2929 3 is be VBZ cord-022526-j9kg00qf 2929 4 a a DT cord-022526-j9kg00qf 2929 5 key key JJ cord-022526-j9kg00qf 2929 6 regulator regulator NN cord-022526-j9kg00qf 2929 7 of of IN cord-022526-j9kg00qf 2929 8 mucosal mucosal JJ cord-022526-j9kg00qf 2929 9 blood blood NN cord-022526-j9kg00qf 2929 10 flow flow NN cord-022526-j9kg00qf 2929 11 and and CC cord-022526-j9kg00qf 2929 12 prostaglandin prostaglandin NN cord-022526-j9kg00qf 2929 13 synthesis synthesis NN cord-022526-j9kg00qf 2929 14 and and CC cord-022526-j9kg00qf 2929 15 thus thus RB cord-022526-j9kg00qf 2929 16 may may MD cord-022526-j9kg00qf 2929 17 play play VB cord-022526-j9kg00qf 2929 18 a a DT cord-022526-j9kg00qf 2929 19 role role NN cord-022526-j9kg00qf 2929 20 in in IN cord-022526-j9kg00qf 2929 21 mucosal mucosal JJ cord-022526-j9kg00qf 2929 22 protection protection NN cord-022526-j9kg00qf 2929 23 . . . cord-022526-j9kg00qf 2930 1 45 45 CD cord-022526-j9kg00qf 2930 2 Dietary dietary JJ cord-022526-j9kg00qf 2930 3 factors factor NNS cord-022526-j9kg00qf 2930 4 also also RB cord-022526-j9kg00qf 2930 5 have have VBP cord-022526-j9kg00qf 2930 6 been be VBN cord-022526-j9kg00qf 2930 7 implicated implicate VBN cord-022526-j9kg00qf 2930 8 in in IN cord-022526-j9kg00qf 2930 9 ulcer ulcer NN cord-022526-j9kg00qf 2930 10 disease disease NN cord-022526-j9kg00qf 2930 11 . . . cord-022526-j9kg00qf 2931 1 Horses horse NNS cord-022526-j9kg00qf 2931 2 in in IN cord-022526-j9kg00qf 2931 3 race race NN cord-022526-j9kg00qf 2931 4 training training NN cord-022526-j9kg00qf 2931 5 have have VBP cord-022526-j9kg00qf 2931 6 a a DT cord-022526-j9kg00qf 2931 7 high high JJ cord-022526-j9kg00qf 2931 8 incidence incidence NN cord-022526-j9kg00qf 2931 9 of of IN cord-022526-j9kg00qf 2931 10 gastric gastric JJ cord-022526-j9kg00qf 2931 11 ulceration ulceration NN cord-022526-j9kg00qf 2931 12 and and CC cord-022526-j9kg00qf 2931 13 frequently frequently RB cord-022526-j9kg00qf 2931 14 are be VBP cord-022526-j9kg00qf 2931 15 fed feed VBN cord-022526-j9kg00qf 2931 16 high high JJ cord-022526-j9kg00qf 2931 17 - - HYPH cord-022526-j9kg00qf 2931 18 concentrate concentrate NN cord-022526-j9kg00qf 2931 19 , , , cord-022526-j9kg00qf 2931 20 low low JJ cord-022526-j9kg00qf 2931 21 - - HYPH cord-022526-j9kg00qf 2931 22 roughage roughage NN cord-022526-j9kg00qf 2931 23 diets diet NNS cord-022526-j9kg00qf 2931 24 . . . cord-022526-j9kg00qf 2932 1 In in IN cord-022526-j9kg00qf 2932 2 one one CD cord-022526-j9kg00qf 2932 3 study study NN cord-022526-j9kg00qf 2932 4 , , , cord-022526-j9kg00qf 2932 5 higher high JJR cord-022526-j9kg00qf 2932 6 volatile volatile JJ cord-022526-j9kg00qf 2932 7 fatty fatty JJ cord-022526-j9kg00qf 2932 8 acid acid NN cord-022526-j9kg00qf 2932 9 ( ( -LRB- cord-022526-j9kg00qf 2932 10 acetic acetic JJ cord-022526-j9kg00qf 2932 11 , , , cord-022526-j9kg00qf 2932 12 propionic propionic NN cord-022526-j9kg00qf 2932 13 , , , cord-022526-j9kg00qf 2932 14 and and CC cord-022526-j9kg00qf 2932 15 isovaleric isovaleric JJ cord-022526-j9kg00qf 2932 16 acid acid NN cord-022526-j9kg00qf 2932 17 ) ) -RRB- cord-022526-j9kg00qf 2932 18 concentrations concentration NNS cord-022526-j9kg00qf 2932 19 , , , cord-022526-j9kg00qf 2932 20 higher high JJR cord-022526-j9kg00qf 2932 21 gastric gastric JJ cord-022526-j9kg00qf 2932 22 juice juice NN cord-022526-j9kg00qf 2932 23 pH ph NN cord-022526-j9kg00qf 2932 24 , , , cord-022526-j9kg00qf 2932 25 and and CC cord-022526-j9kg00qf 2932 26 lower low JJR cord-022526-j9kg00qf 2932 27 number number NN cord-022526-j9kg00qf 2932 28 and and CC cord-022526-j9kg00qf 2932 29 severity severity NN cord-022526-j9kg00qf 2932 30 of of IN cord-022526-j9kg00qf 2932 31 nonglandular nonglandular JJ cord-022526-j9kg00qf 2932 32 ulceration ulceration NN cord-022526-j9kg00qf 2932 33 were be VBD cord-022526-j9kg00qf 2932 34 documented document VBN cord-022526-j9kg00qf 2932 35 after after IN cord-022526-j9kg00qf 2932 36 feeding feed VBG cord-022526-j9kg00qf 2932 37 an an DT cord-022526-j9kg00qf 2932 38 alfalfa alfalfa NN cord-022526-j9kg00qf 2932 39 hay hay NN cord-022526-j9kg00qf 2932 40 - - HYPH cord-022526-j9kg00qf 2932 41 grain grain NN cord-022526-j9kg00qf 2932 42 diet diet NN cord-022526-j9kg00qf 2932 43 compared compare VBN cord-022526-j9kg00qf 2932 44 with with IN cord-022526-j9kg00qf 2932 45 a a DT cord-022526-j9kg00qf 2932 46 bromegrass bromegrass NNP cord-022526-j9kg00qf 2932 47 hay hay NN cord-022526-j9kg00qf 2932 48 diet diet NN cord-022526-j9kg00qf 2932 49 . . . cord-022526-j9kg00qf 2933 1 46 46 CD cord-022526-j9kg00qf 2934 1 However however RB cord-022526-j9kg00qf 2934 2 , , , cord-022526-j9kg00qf 2934 3 many many JJ cord-022526-j9kg00qf 2934 4 factors factor NNS cord-022526-j9kg00qf 2934 5 differed differ VBD cord-022526-j9kg00qf 2934 6 between between IN cord-022526-j9kg00qf 2934 7 the the DT cord-022526-j9kg00qf 2934 8 diets diet NNS cord-022526-j9kg00qf 2934 9 , , , cord-022526-j9kg00qf 2934 10 such such JJ cord-022526-j9kg00qf 2934 11 as as IN cord-022526-j9kg00qf 2934 12 digestible digestible JJ cord-022526-j9kg00qf 2934 13 energy energy NN cord-022526-j9kg00qf 2934 14 , , , cord-022526-j9kg00qf 2934 15 bulk bulk NN cord-022526-j9kg00qf 2934 16 , , , cord-022526-j9kg00qf 2934 17 crude crude JJ cord-022526-j9kg00qf 2934 18 protein protein NN cord-022526-j9kg00qf 2934 19 , , , cord-022526-j9kg00qf 2934 20 and and CC cord-022526-j9kg00qf 2934 21 mineral mineral NN cord-022526-j9kg00qf 2934 22 content content NN cord-022526-j9kg00qf 2934 23 ( ( -LRB- cord-022526-j9kg00qf 2934 24 especially especially RB cord-022526-j9kg00qf 2934 25 calcium calcium NN cord-022526-j9kg00qf 2934 26 ) ) -RRB- cord-022526-j9kg00qf 2934 27 . . . cord-022526-j9kg00qf 2935 1 Thus thus RB cord-022526-j9kg00qf 2935 2 dietary dietary JJ cord-022526-j9kg00qf 2935 3 factors factor NNS cord-022526-j9kg00qf 2935 4 represent represent VBP cord-022526-j9kg00qf 2935 5 an an DT cord-022526-j9kg00qf 2935 6 important important JJ cord-022526-j9kg00qf 2935 7 area area NN cord-022526-j9kg00qf 2935 8 of of IN cord-022526-j9kg00qf 2935 9 further further JJ cord-022526-j9kg00qf 2935 10 investigation investigation NN cord-022526-j9kg00qf 2935 11 in in IN cord-022526-j9kg00qf 2935 12 the the DT cord-022526-j9kg00qf 2935 13 pathophysiology pathophysiology NN cord-022526-j9kg00qf 2935 14 of of IN cord-022526-j9kg00qf 2935 15 EGUS egu NNS cord-022526-j9kg00qf 2935 16 , , , cord-022526-j9kg00qf 2935 17 particularly particularly RB cord-022526-j9kg00qf 2935 18 squamous squamous JJ cord-022526-j9kg00qf 2935 19 ulceration ulceration NN cord-022526-j9kg00qf 2935 20 . . . cord-022526-j9kg00qf 2936 1 The the DT cord-022526-j9kg00qf 2936 2 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 2936 3 correlation correlation NN cord-022526-j9kg00qf 2936 4 between between IN cord-022526-j9kg00qf 2936 5 exercise exercise NN cord-022526-j9kg00qf 2936 6 and and CC cord-022526-j9kg00qf 2936 7 squamous squamous JJ cord-022526-j9kg00qf 2936 8 ulcer ulcer NN cord-022526-j9kg00qf 2936 9 disease disease NN cord-022526-j9kg00qf 2936 10 has have VBZ cord-022526-j9kg00qf 2936 11 not not RB cord-022526-j9kg00qf 2936 12 yet yet RB cord-022526-j9kg00qf 2936 13 been be VBN cord-022526-j9kg00qf 2936 14 defined define VBN cord-022526-j9kg00qf 2936 15 despite despite IN cord-022526-j9kg00qf 2936 16 the the DT cord-022526-j9kg00qf 2936 17 high high JJ cord-022526-j9kg00qf 2936 18 prevalence prevalence NN cord-022526-j9kg00qf 2936 19 of of IN cord-022526-j9kg00qf 2936 20 ulceration ulceration NN cord-022526-j9kg00qf 2936 21 in in IN cord-022526-j9kg00qf 2936 22 performance performance NN cord-022526-j9kg00qf 2936 23 horses horse NNS cord-022526-j9kg00qf 2936 24 . . . cord-022526-j9kg00qf 2937 1 Preliminary preliminary JJ cord-022526-j9kg00qf 2937 2 work work NN cord-022526-j9kg00qf 2937 3 suggests suggest VBZ cord-022526-j9kg00qf 2937 4 that that IN cord-022526-j9kg00qf 2937 5 gastric gastric JJ cord-022526-j9kg00qf 2937 6 compression compression NN cord-022526-j9kg00qf 2937 7 occurs occur VBZ cord-022526-j9kg00qf 2937 8 during during IN cord-022526-j9kg00qf 2937 9 treadmill treadmill NN cord-022526-j9kg00qf 2937 10 exercise exercise NN cord-022526-j9kg00qf 2937 11 , , , cord-022526-j9kg00qf 2937 12 presumably presumably RB cord-022526-j9kg00qf 2937 13 because because IN cord-022526-j9kg00qf 2937 14 of of IN cord-022526-j9kg00qf 2937 15 an an DT cord-022526-j9kg00qf 2937 16 increase increase NN cord-022526-j9kg00qf 2937 17 in in IN cord-022526-j9kg00qf 2937 18 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 2937 19 pressure pressure NN cord-022526-j9kg00qf 2937 20 . . . cord-022526-j9kg00qf 2938 1 47 47 CD cord-022526-j9kg00qf 2939 1 Such such JJ cord-022526-j9kg00qf 2939 2 contracture contracture NN cord-022526-j9kg00qf 2939 3 could could MD cord-022526-j9kg00qf 2939 4 result result VB cord-022526-j9kg00qf 2939 5 in in IN cord-022526-j9kg00qf 2939 6 increased increase VBN cord-022526-j9kg00qf 2939 7 acid acid NN cord-022526-j9kg00qf 2939 8 exposure exposure NN cord-022526-j9kg00qf 2939 9 to to IN cord-022526-j9kg00qf 2939 10 the the DT cord-022526-j9kg00qf 2939 11 squamous squamous JJ cord-022526-j9kg00qf 2939 12 mucosa mucosa NN cord-022526-j9kg00qf 2939 13 by by IN cord-022526-j9kg00qf 2939 14 raising raise VBG cord-022526-j9kg00qf 2939 15 the the DT cord-022526-j9kg00qf 2939 16 fill fill JJ cord-022526-j9kg00qf 2939 17 line line NN cord-022526-j9kg00qf 2939 18 of of IN cord-022526-j9kg00qf 2939 19 gastric gastric JJ cord-022526-j9kg00qf 2939 20 contents content NNS cord-022526-j9kg00qf 2939 21 . . . cord-022526-j9kg00qf 2940 1 Further further JJ cord-022526-j9kg00qf 2940 2 studies study NNS cord-022526-j9kg00qf 2940 3 in in IN cord-022526-j9kg00qf 2940 4 this this DT cord-022526-j9kg00qf 2940 5 laboratory laboratory NN cord-022526-j9kg00qf 2940 6 have have VBP cord-022526-j9kg00qf 2940 7 provided provide VBN cord-022526-j9kg00qf 2940 8 support support NN cord-022526-j9kg00qf 2940 9 for for IN cord-022526-j9kg00qf 2940 10 this this DT cord-022526-j9kg00qf 2940 11 theory theory NN cord-022526-j9kg00qf 2940 12 by by IN cord-022526-j9kg00qf 2940 13 demonstrating demonstrate VBG cord-022526-j9kg00qf 2940 14 a a DT cord-022526-j9kg00qf 2940 15 high high JJ cord-022526-j9kg00qf 2940 16 pH ph NN cord-022526-j9kg00qf 2940 17 in in IN cord-022526-j9kg00qf 2940 18 the the DT cord-022526-j9kg00qf 2940 19 proximal proximal JJ cord-022526-j9kg00qf 2940 20 stomach stomach NN cord-022526-j9kg00qf 2940 21 , , , cord-022526-j9kg00qf 2940 22 immediately immediately RB cord-022526-j9kg00qf 2940 23 distal distal JJ cord-022526-j9kg00qf 2940 24 to to IN cord-022526-j9kg00qf 2940 25 the the DT cord-022526-j9kg00qf 2940 26 lower low JJR cord-022526-j9kg00qf 2940 27 esophageal esophageal JJ cord-022526-j9kg00qf 2940 28 sphincter sphincter NN cord-022526-j9kg00qf 2940 29 , , , cord-022526-j9kg00qf 2940 30 during during IN cord-022526-j9kg00qf 2940 31 resting rest VBG cord-022526-j9kg00qf 2940 32 conditions condition NNS cord-022526-j9kg00qf 2940 33 that that WDT cord-022526-j9kg00qf 2940 34 decreases decrease VBZ cord-022526-j9kg00qf 2940 35 during during IN cord-022526-j9kg00qf 2940 36 treadmill treadmill NN cord-022526-j9kg00qf 2940 37 exercise exercise NN cord-022526-j9kg00qf 2940 38 ( ( -LRB- cord-022526-j9kg00qf 2940 39 M. M. NNP cord-022526-j9kg00qf 2940 40 Lorenzo Lorenzo NNP cord-022526-j9kg00qf 2940 41 - - HYPH cord-022526-j9kg00qf 2940 42 Figueras Figueras NNP cord-022526-j9kg00qf 2940 43 and and CC cord-022526-j9kg00qf 2940 44 A.M. A.M. NNP cord-022526-j9kg00qf 2940 45 Merritt Merritt NNP cord-022526-j9kg00qf 2940 46 , , , cord-022526-j9kg00qf 2940 47 personal personal JJ cord-022526-j9kg00qf 2940 48 communication communication NN cord-022526-j9kg00qf 2940 49 , , , cord-022526-j9kg00qf 2940 50 2002 2002 CD cord-022526-j9kg00qf 2940 51 ) ) -RRB- cord-022526-j9kg00qf 2940 52 . . . cord-022526-j9kg00qf 2941 1 Risk risk NN cord-022526-j9kg00qf 2941 2 factors factor NNS cord-022526-j9kg00qf 2941 3 associated associate VBN cord-022526-j9kg00qf 2941 4 with with IN cord-022526-j9kg00qf 2941 5 gastric gastric JJ cord-022526-j9kg00qf 2941 6 ulceration ulceration NN cord-022526-j9kg00qf 2941 7 include include VBP cord-022526-j9kg00qf 2941 8 gender gender NN cord-022526-j9kg00qf 2941 9 and and CC cord-022526-j9kg00qf 2941 10 age age NN cord-022526-j9kg00qf 2941 11 , , , cord-022526-j9kg00qf 2941 12 and and CC cord-022526-j9kg00qf 2941 13 the the DT cord-022526-j9kg00qf 2941 14 reported report VBN cord-022526-j9kg00qf 2941 15 prevalence prevalence NN cord-022526-j9kg00qf 2941 16 of of IN cord-022526-j9kg00qf 2941 17 gastric gastric JJ cord-022526-j9kg00qf 2941 18 ulcers ulcer NNS cord-022526-j9kg00qf 2941 19 has have VBZ cord-022526-j9kg00qf 2941 20 increased increase VBN cord-022526-j9kg00qf 2941 21 over over IN cord-022526-j9kg00qf 2941 22 time time NN cord-022526-j9kg00qf 2941 23 . . . cord-022526-j9kg00qf 2942 1 In in IN cord-022526-j9kg00qf 2942 2 one one CD cord-022526-j9kg00qf 2942 3 study study NN cord-022526-j9kg00qf 2942 4 , , , cord-022526-j9kg00qf 2942 5 ulcers ulcer NNS cord-022526-j9kg00qf 2942 6 were be VBD cord-022526-j9kg00qf 2942 7 found find VBN cord-022526-j9kg00qf 2942 8 more more RBR cord-022526-j9kg00qf 2942 9 commonly commonly RB cord-022526-j9kg00qf 2942 10 in in IN cord-022526-j9kg00qf 2942 11 stallions stallion NNS cord-022526-j9kg00qf 2942 12 , , , cord-022526-j9kg00qf 2942 13 and and CC cord-022526-j9kg00qf 2942 14 the the DT cord-022526-j9kg00qf 2942 15 prevalence prevalence NN cord-022526-j9kg00qf 2942 16 of of IN cord-022526-j9kg00qf 2942 17 gastric gastric JJ cord-022526-j9kg00qf 2942 18 ulceration ulceration NN cord-022526-j9kg00qf 2942 19 decreased decrease VBD cord-022526-j9kg00qf 2942 20 with with IN cord-022526-j9kg00qf 2942 21 age age NN cord-022526-j9kg00qf 2942 22 , , , cord-022526-j9kg00qf 2942 23 independent independent JJ cord-022526-j9kg00qf 2942 24 of of IN cord-022526-j9kg00qf 2942 25 gender gender NN cord-022526-j9kg00qf 2942 26 , , , cord-022526-j9kg00qf 2942 27 although although IN cord-022526-j9kg00qf 2942 28 this this DT cord-022526-j9kg00qf 2942 29 trend trend NN cord-022526-j9kg00qf 2942 30 was be VBD cord-022526-j9kg00qf 2942 31 only only RB cord-022526-j9kg00qf 2942 32 significant significant JJ cord-022526-j9kg00qf 2942 33 in in IN cord-022526-j9kg00qf 2942 34 the the DT cord-022526-j9kg00qf 2942 35 population population NN cord-022526-j9kg00qf 2942 36 of of IN cord-022526-j9kg00qf 2942 37 Standardbred Standardbred NNP cord-022526-j9kg00qf 2942 38 trotters trotter NNS cord-022526-j9kg00qf 2942 39 . . . cord-022526-j9kg00qf 2943 1 10 10 CD cord-022526-j9kg00qf 2944 1 Interestingly interestingly RB cord-022526-j9kg00qf 2944 2 , , , cord-022526-j9kg00qf 2944 3 the the DT cord-022526-j9kg00qf 2944 4 frequency frequency NN cord-022526-j9kg00qf 2944 5 of of IN cord-022526-j9kg00qf 2944 6 gastric gastric JJ cord-022526-j9kg00qf 2944 7 ulceration ulceration NN cord-022526-j9kg00qf 2944 8 increased increase VBD cord-022526-j9kg00qf 2944 9 from from IN cord-022526-j9kg00qf 2944 10 less less JJR cord-022526-j9kg00qf 2944 11 than than IN cord-022526-j9kg00qf 2944 12 6 6 CD cord-022526-j9kg00qf 2944 13 % % NN cord-022526-j9kg00qf 2944 14 before before IN cord-022526-j9kg00qf 2944 15 1945 1945 CD cord-022526-j9kg00qf 2944 16 to to IN cord-022526-j9kg00qf 2944 17 approximately approximately RB cord-022526-j9kg00qf 2944 18 18 18 CD cord-022526-j9kg00qf 2944 19 % % NN cord-022526-j9kg00qf 2944 20 after after IN cord-022526-j9kg00qf 2944 21 1975 1975 CD cord-022526-j9kg00qf 2944 22 . . . cord-022526-j9kg00qf 2945 1 In in IN cord-022526-j9kg00qf 2945 2 a a DT cord-022526-j9kg00qf 2945 3 study study NN cord-022526-j9kg00qf 2945 4 of of IN cord-022526-j9kg00qf 2945 5 Thoroughbred thoroughbred JJ cord-022526-j9kg00qf 2945 6 horses horse NNS cord-022526-j9kg00qf 2945 7 in in IN cord-022526-j9kg00qf 2945 8 race race NN cord-022526-j9kg00qf 2945 9 training training NN cord-022526-j9kg00qf 2945 10 , , , cord-022526-j9kg00qf 2945 11 an an DT cord-022526-j9kg00qf 2945 12 increase increase NN cord-022526-j9kg00qf 2945 13 in in IN cord-022526-j9kg00qf 2945 14 squamous squamous JJ cord-022526-j9kg00qf 2945 15 ulcer ulcer NN cord-022526-j9kg00qf 2945 16 severity severity NN cord-022526-j9kg00qf 2945 17 was be VBD cord-022526-j9kg00qf 2945 18 noted note VBN cord-022526-j9kg00qf 2945 19 in in IN cord-022526-j9kg00qf 2945 20 horses horse NNS cord-022526-j9kg00qf 2945 21 3 3 CD cord-022526-j9kg00qf 2945 22 years year NNS cord-022526-j9kg00qf 2945 23 old old JJ cord-022526-j9kg00qf 2945 24 or or CC cord-022526-j9kg00qf 2945 25 older old JJR cord-022526-j9kg00qf 2945 26 and and CC cord-022526-j9kg00qf 2945 27 in in IN cord-022526-j9kg00qf 2945 28 those those DT cord-022526-j9kg00qf 2945 29 horses horse NNS cord-022526-j9kg00qf 2945 30 that that WDT cord-022526-j9kg00qf 2945 31 had have VBD cord-022526-j9kg00qf 2945 32 raced race VBN cord-022526-j9kg00qf 2945 33 . . . cord-022526-j9kg00qf 2946 1 4 4 LS cord-022526-j9kg00qf 2947 1 In in IN cord-022526-j9kg00qf 2947 2 the the DT cord-022526-j9kg00qf 2947 3 same same JJ cord-022526-j9kg00qf 2947 4 study study NN cord-022526-j9kg00qf 2947 5 , , , cord-022526-j9kg00qf 2947 6 severity severity NN cord-022526-j9kg00qf 2947 7 of of IN cord-022526-j9kg00qf 2947 8 glandular glandular JJ cord-022526-j9kg00qf 2947 9 lesions lesion NNS cord-022526-j9kg00qf 2947 10 did do VBD cord-022526-j9kg00qf 2947 11 not not RB cord-022526-j9kg00qf 2947 12 change change VB cord-022526-j9kg00qf 2947 13 between between IN cord-022526-j9kg00qf 2947 14 examinations examination NNS cord-022526-j9kg00qf 2947 15 , , , cord-022526-j9kg00qf 2947 16 and and CC cord-022526-j9kg00qf 2947 17 age age NN cord-022526-j9kg00qf 2947 18 ( ( -LRB- cord-022526-j9kg00qf 2947 19 > > NFP cord-022526-j9kg00qf 2947 20 3 3 CD cord-022526-j9kg00qf 2947 21 years year NNS cord-022526-j9kg00qf 2947 22 ) ) -RRB- cord-022526-j9kg00qf 2947 23 was be VBD cord-022526-j9kg00qf 2947 24 the the DT cord-022526-j9kg00qf 2947 25 only only JJ cord-022526-j9kg00qf 2947 26 factor factor NN cord-022526-j9kg00qf 2947 27 associated associate VBN cord-022526-j9kg00qf 2947 28 with with IN cord-022526-j9kg00qf 2947 29 glandular glandular JJ cord-022526-j9kg00qf 2947 30 lesion lesion NN cord-022526-j9kg00qf 2947 31 severity severity NN cord-022526-j9kg00qf 2947 32 . . . cord-022526-j9kg00qf 2948 1 Several several JJ cord-022526-j9kg00qf 2948 2 studies study NNS cord-022526-j9kg00qf 2948 3 have have VBP cord-022526-j9kg00qf 2948 4 failed fail VBN cord-022526-j9kg00qf 2948 5 to to TO cord-022526-j9kg00qf 2948 6 document document VB cord-022526-j9kg00qf 2948 7 a a DT cord-022526-j9kg00qf 2948 8 correlation correlation NN cord-022526-j9kg00qf 2948 9 between between IN cord-022526-j9kg00qf 2948 10 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 2948 11 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 2948 12 drug drug NN cord-022526-j9kg00qf 2948 13 ( ( -LRB- cord-022526-j9kg00qf 2948 14 NSAID NSAID NNP cord-022526-j9kg00qf 2948 15 ) ) -RRB- cord-022526-j9kg00qf 2948 16 administration administration NN cord-022526-j9kg00qf 2948 17 and and CC cord-022526-j9kg00qf 2948 18 naturally naturally RB cord-022526-j9kg00qf 2948 19 occurring occur VBG cord-022526-j9kg00qf 2948 20 ulcer ulcer NN cord-022526-j9kg00qf 2948 21 disease disease NN cord-022526-j9kg00qf 2948 22 . . . cord-022526-j9kg00qf 2949 1 3 3 CD cord-022526-j9kg00qf 2949 2 , , , cord-022526-j9kg00qf 2949 3 4 4 CD cord-022526-j9kg00qf 2949 4 , , , cord-022526-j9kg00qf 2949 5 6 6 CD cord-022526-j9kg00qf 2949 6 , , , cord-022526-j9kg00qf 2949 7 7 7 CD cord-022526-j9kg00qf 2949 8 , , , cord-022526-j9kg00qf 2949 9 10 10 CD cord-022526-j9kg00qf 2950 1 However however RB cord-022526-j9kg00qf 2950 2 , , , cord-022526-j9kg00qf 2950 3 NSAID NSAID NNP cord-022526-j9kg00qf 2950 4 administration administration NN cord-022526-j9kg00qf 2950 5 is be VBZ cord-022526-j9kg00qf 2950 6 a a DT cord-022526-j9kg00qf 2950 7 well well RB cord-022526-j9kg00qf 2950 8 - - HYPH cord-022526-j9kg00qf 2950 9 known know VBN cord-022526-j9kg00qf 2950 10 cause cause NN cord-022526-j9kg00qf 2950 11 of of IN cord-022526-j9kg00qf 2950 12 gastric gastric JJ cord-022526-j9kg00qf 2950 13 ulceration ulceration NN cord-022526-j9kg00qf 2950 14 under under IN cord-022526-j9kg00qf 2950 15 experimental experimental JJ cord-022526-j9kg00qf 2950 16 conditions condition NNS cord-022526-j9kg00qf 2950 17 . . . cord-022526-j9kg00qf 2951 1 [ [ -LRB- cord-022526-j9kg00qf 2951 2 48 48 CD cord-022526-j9kg00qf 2951 3 ] ] -RRB- cord-022526-j9kg00qf 2951 4 [ [ -LRB- cord-022526-j9kg00qf 2951 5 49 49 CD cord-022526-j9kg00qf 2951 6 ] ] -RRB- cord-022526-j9kg00qf 2951 7 [ [ -LRB- cord-022526-j9kg00qf 2951 8 50 50 CD cord-022526-j9kg00qf 2951 9 ] ] -RRB- cord-022526-j9kg00qf 2951 10 [ [ -LRB- cord-022526-j9kg00qf 2951 11 51 51 CD cord-022526-j9kg00qf 2951 12 ] ] -RRB- cord-022526-j9kg00qf 2952 1 [ [ -LRB- cord-022526-j9kg00qf 2952 2 52 52 CD cord-022526-j9kg00qf 2952 3 ] ] -RRB- cord-022526-j9kg00qf 2952 4 NSAID NSAID NNP cord-022526-j9kg00qf 2952 5 - - HYPH cord-022526-j9kg00qf 2952 6 related relate VBN cord-022526-j9kg00qf 2952 7 ulceration ulceration NN cord-022526-j9kg00qf 2952 8 typically typically RB cord-022526-j9kg00qf 2952 9 is be VBZ cord-022526-j9kg00qf 2952 10 described describe VBN cord-022526-j9kg00qf 2952 11 as as IN cord-022526-j9kg00qf 2952 12 predominantly predominantly RB cord-022526-j9kg00qf 2952 13 glandular glandular JJ cord-022526-j9kg00qf 2952 14 , , , cord-022526-j9kg00qf 2952 15 although although IN cord-022526-j9kg00qf 2952 16 nonglandular nonglandular JJ cord-022526-j9kg00qf 2952 17 ulceration ulceration NN cord-022526-j9kg00qf 2952 18 also also RB cord-022526-j9kg00qf 2952 19 can can MD cord-022526-j9kg00qf 2952 20 occur occur VB cord-022526-j9kg00qf 2952 21 by by IN cord-022526-j9kg00qf 2952 22 a a DT cord-022526-j9kg00qf 2952 23 mechanism mechanism NN cord-022526-j9kg00qf 2952 24 that that WDT cord-022526-j9kg00qf 2952 25 has have VBZ cord-022526-j9kg00qf 2952 26 not not RB cord-022526-j9kg00qf 2952 27 yet yet RB cord-022526-j9kg00qf 2952 28 been be VBN cord-022526-j9kg00qf 2952 29 characterized characterize VBN cord-022526-j9kg00qf 2952 30 fully fully RB cord-022526-j9kg00qf 2952 31 . . . cord-022526-j9kg00qf 2953 1 NSAIDS NSAIDS NNP cord-022526-j9kg00qf 2953 2 cause cause VBP cord-022526-j9kg00qf 2953 3 a a DT cord-022526-j9kg00qf 2953 4 decrease decrease NN cord-022526-j9kg00qf 2953 5 in in IN cord-022526-j9kg00qf 2953 6 prostaglandin prostaglandin NN cord-022526-j9kg00qf 2953 7 E e NN cord-022526-j9kg00qf 2953 8 2 2 CD cord-022526-j9kg00qf 2953 9 synthesis synthesis NN cord-022526-j9kg00qf 2953 10 because because IN cord-022526-j9kg00qf 2953 11 of of IN cord-022526-j9kg00qf 2953 12 inhibition inhibition NN cord-022526-j9kg00qf 2953 13 of of IN cord-022526-j9kg00qf 2953 14 the the DT cord-022526-j9kg00qf 2953 15 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 2953 16 pathway pathway NN cord-022526-j9kg00qf 2953 17 . . . cord-022526-j9kg00qf 2954 1 Therefore therefore RB cord-022526-j9kg00qf 2954 2 a a DT cord-022526-j9kg00qf 2954 3 resultant resultant JJ cord-022526-j9kg00qf 2954 4 decrease decrease NN cord-022526-j9kg00qf 2954 5 in in IN cord-022526-j9kg00qf 2954 6 glandular glandular JJ cord-022526-j9kg00qf 2954 7 mucosal mucosal JJ cord-022526-j9kg00qf 2954 8 protection protection NN cord-022526-j9kg00qf 2954 9 , , , cord-022526-j9kg00qf 2954 10 most most RBS cord-022526-j9kg00qf 2954 11 notably notably RB cord-022526-j9kg00qf 2954 12 via via IN cord-022526-j9kg00qf 2954 13 decreased decrease VBN cord-022526-j9kg00qf 2954 14 mucosal mucosal JJ cord-022526-j9kg00qf 2954 15 blood blood NN cord-022526-j9kg00qf 2954 16 flow flow NN cord-022526-j9kg00qf 2954 17 and and CC cord-022526-j9kg00qf 2954 18 mucus mucus NN cord-022526-j9kg00qf 2954 19 production production NN cord-022526-j9kg00qf 2954 20 , , , cord-022526-j9kg00qf 2954 21 is be VBZ cord-022526-j9kg00qf 2954 22 the the DT cord-022526-j9kg00qf 2954 23 most most RBS cord-022526-j9kg00qf 2954 24 likely likely JJ cord-022526-j9kg00qf 2954 25 mechanism mechanism NN cord-022526-j9kg00qf 2954 26 of of IN cord-022526-j9kg00qf 2954 27 action action NN cord-022526-j9kg00qf 2954 28 . . . cord-022526-j9kg00qf 2955 1 In in IN cord-022526-j9kg00qf 2955 2 one one CD cord-022526-j9kg00qf 2955 3 study study NN cord-022526-j9kg00qf 2955 4 , , , cord-022526-j9kg00qf 2955 5 however however RB cord-022526-j9kg00qf 2955 6 , , , cord-022526-j9kg00qf 2955 7 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 2955 8 administration administration NN cord-022526-j9kg00qf 2955 9 resulted result VBD cord-022526-j9kg00qf 2955 10 in in IN cord-022526-j9kg00qf 2955 11 ulceration ulceration NN cord-022526-j9kg00qf 2955 12 of of IN cord-022526-j9kg00qf 2955 13 the the DT cord-022526-j9kg00qf 2955 14 glandular glandular JJ cord-022526-j9kg00qf 2955 15 mucosa mucosa NN cord-022526-j9kg00qf 2955 16 at at IN cord-022526-j9kg00qf 2955 17 the the DT cord-022526-j9kg00qf 2955 18 pyloric pyloric JJ cord-022526-j9kg00qf 2955 19 antrum antrum NN cord-022526-j9kg00qf 2955 20 but but CC cord-022526-j9kg00qf 2955 21 did do VBD cord-022526-j9kg00qf 2955 22 not not RB cord-022526-j9kg00qf 2955 23 alter alter VB cord-022526-j9kg00qf 2955 24 mucosal mucosal JJ cord-022526-j9kg00qf 2955 25 prostaglandin prostaglandin NN cord-022526-j9kg00qf 2955 26 E e NN cord-022526-j9kg00qf 2955 27 2 2 CD cord-022526-j9kg00qf 2955 28 concentration concentration NN cord-022526-j9kg00qf 2955 29 significantly significantly RB cord-022526-j9kg00qf 2955 30 . . . cord-022526-j9kg00qf 2956 1 52 52 CD cord-022526-j9kg00qf 2956 2 Clinical clinical JJ cord-022526-j9kg00qf 2956 3 signs sign NNS cord-022526-j9kg00qf 2956 4 typically typically RB cord-022526-j9kg00qf 2956 5 associated associate VBN cord-022526-j9kg00qf 2956 6 with with IN cord-022526-j9kg00qf 2956 7 gastric gastric JJ cord-022526-j9kg00qf 2956 8 ulceration ulceration NN cord-022526-j9kg00qf 2956 9 in in IN cord-022526-j9kg00qf 2956 10 foals foal NNS cord-022526-j9kg00qf 2956 11 include include VBP cord-022526-j9kg00qf 2956 12 poor poor JJ cord-022526-j9kg00qf 2956 13 appetite appetite NN cord-022526-j9kg00qf 2956 14 , , , cord-022526-j9kg00qf 2956 15 diarrhea diarrhea NN cord-022526-j9kg00qf 2956 16 , , , cord-022526-j9kg00qf 2956 17 and and CC cord-022526-j9kg00qf 2956 18 colic colic NN cord-022526-j9kg00qf 2956 19 . . . cord-022526-j9kg00qf 2957 1 Many many JJ cord-022526-j9kg00qf 2957 2 foals foal NNS cord-022526-j9kg00qf 2957 3 probably probably RB cord-022526-j9kg00qf 2957 4 never never RB cord-022526-j9kg00qf 2957 5 exhibit exhibit VBP cord-022526-j9kg00qf 2957 6 clinical clinical JJ cord-022526-j9kg00qf 2957 7 signs sign NNS cord-022526-j9kg00qf 2957 8 , , , cord-022526-j9kg00qf 2957 9 and and CC cord-022526-j9kg00qf 2957 10 some some DT cord-022526-j9kg00qf 2957 11 do do VBP cord-022526-j9kg00qf 2957 12 not not RB cord-022526-j9kg00qf 2957 13 exhibit exhibit VB cord-022526-j9kg00qf 2957 14 clinical clinical JJ cord-022526-j9kg00qf 2957 15 signs sign NNS cord-022526-j9kg00qf 2957 16 until until IN cord-022526-j9kg00qf 2957 17 ulceration ulceration NN cord-022526-j9kg00qf 2957 18 is be VBZ cord-022526-j9kg00qf 2957 19 severe severe JJ cord-022526-j9kg00qf 2957 20 or or CC cord-022526-j9kg00qf 2957 21 fatal fatal JJ cord-022526-j9kg00qf 2957 22 perforation perforation NN cord-022526-j9kg00qf 2957 23 has have VBZ cord-022526-j9kg00qf 2957 24 occurred occur VBN cord-022526-j9kg00qf 2957 25 . . . cord-022526-j9kg00qf 2958 1 Glandular glandular JJ cord-022526-j9kg00qf 2958 2 ulceration ulceration NN cord-022526-j9kg00qf 2958 3 typically typically RB cord-022526-j9kg00qf 2958 4 is be VBZ cord-022526-j9kg00qf 2958 5 considered consider VBN cord-022526-j9kg00qf 2958 6 the the DT cord-022526-j9kg00qf 2958 7 most most RBS cord-022526-j9kg00qf 2958 8 clinically clinically RB cord-022526-j9kg00qf 2958 9 significant significant JJ cord-022526-j9kg00qf 2958 10 type type NN cord-022526-j9kg00qf 2958 11 of of IN cord-022526-j9kg00qf 2958 12 disease disease NN cord-022526-j9kg00qf 2958 13 in in IN cord-022526-j9kg00qf 2958 14 this this DT cord-022526-j9kg00qf 2958 15 population population NN cord-022526-j9kg00qf 2958 16 . . . cord-022526-j9kg00qf 2959 1 The the DT cord-022526-j9kg00qf 2959 2 physiologic physiologic JJ cord-022526-j9kg00qf 2959 3 stress stress NN cord-022526-j9kg00qf 2959 4 of of IN cord-022526-j9kg00qf 2959 5 a a DT cord-022526-j9kg00qf 2959 6 concurrent concurrent JJ cord-022526-j9kg00qf 2959 7 illness illness NN cord-022526-j9kg00qf 2959 8 has have VBZ cord-022526-j9kg00qf 2959 9 been be VBN cord-022526-j9kg00qf 2959 10 associated associate VBN cord-022526-j9kg00qf 2959 11 with with IN cord-022526-j9kg00qf 2959 12 gastric gastric JJ cord-022526-j9kg00qf 2959 13 ulceration ulceration NN cord-022526-j9kg00qf 2959 14 in in IN cord-022526-j9kg00qf 2959 15 foals foal NNS cord-022526-j9kg00qf 2959 16 . . . cord-022526-j9kg00qf 2960 1 Retrospectively retrospectively RB cord-022526-j9kg00qf 2960 2 , , , cord-022526-j9kg00qf 2960 3 14 14 CD cord-022526-j9kg00qf 2960 4 ( ( -LRB- cord-022526-j9kg00qf 2960 5 23 23 CD cord-022526-j9kg00qf 2960 6 % % NN cord-022526-j9kg00qf 2960 7 ) ) -RRB- cord-022526-j9kg00qf 2960 8 of of IN cord-022526-j9kg00qf 2960 9 61 61 CD cord-022526-j9kg00qf 2960 10 foals foal NNS cord-022526-j9kg00qf 2960 11 up up IN cord-022526-j9kg00qf 2960 12 to to TO cord-022526-j9kg00qf 2960 13 85 85 CD cord-022526-j9kg00qf 2960 14 days day NNS cord-022526-j9kg00qf 2960 15 of of IN cord-022526-j9kg00qf 2960 16 age age NN cord-022526-j9kg00qf 2960 17 with with IN cord-022526-j9kg00qf 2960 18 a a DT cord-022526-j9kg00qf 2960 19 clinical clinical JJ cord-022526-j9kg00qf 2960 20 disorder disorder NN cord-022526-j9kg00qf 2960 21 were be VBD cord-022526-j9kg00qf 2960 22 found find VBN cord-022526-j9kg00qf 2960 23 to to TO cord-022526-j9kg00qf 2960 24 have have VB cord-022526-j9kg00qf 2960 25 lesions lesion NNS cord-022526-j9kg00qf 2960 26 in in IN cord-022526-j9kg00qf 2960 27 the the DT cord-022526-j9kg00qf 2960 28 gastric gastric JJ cord-022526-j9kg00qf 2960 29 glandular glandular JJ cord-022526-j9kg00qf 2960 30 mucosa mucosa NN cord-022526-j9kg00qf 2960 31 , , , cord-022526-j9kg00qf 2960 32 13 13 CD cord-022526-j9kg00qf 2960 33 and and CC cord-022526-j9kg00qf 2960 34 prospectively prospectively RB cord-022526-j9kg00qf 2960 35 8 8 CD cord-022526-j9kg00qf 2960 36 ( ( -LRB- cord-022526-j9kg00qf 2960 37 40 40 CD cord-022526-j9kg00qf 2960 38 % % NN cord-022526-j9kg00qf 2960 39 ) ) -RRB- cord-022526-j9kg00qf 2960 40 of of IN cord-022526-j9kg00qf 2960 41 20 20 CD cord-022526-j9kg00qf 2960 42 foals foal NNS cord-022526-j9kg00qf 2960 43 up up IN cord-022526-j9kg00qf 2960 44 to to TO cord-022526-j9kg00qf 2960 45 30 30 CD cord-022526-j9kg00qf 2960 46 days day NNS cord-022526-j9kg00qf 2960 47 of of IN cord-022526-j9kg00qf 2960 48 age age NN cord-022526-j9kg00qf 2960 49 with with IN cord-022526-j9kg00qf 2960 50 a a DT cord-022526-j9kg00qf 2960 51 clinical clinical JJ cord-022526-j9kg00qf 2960 52 disorder disorder NN cord-022526-j9kg00qf 2960 53 had have VBD cord-022526-j9kg00qf 2960 54 glandular glandular JJ cord-022526-j9kg00qf 2960 55 ulceration ulceration NN cord-022526-j9kg00qf 2960 56 . . . cord-022526-j9kg00qf 2961 1 53 53 CD cord-022526-j9kg00qf 2962 1 By by IN cord-022526-j9kg00qf 2962 2 contrast contrast NN cord-022526-j9kg00qf 2962 3 , , , cord-022526-j9kg00qf 2962 4 only only RB cord-022526-j9kg00qf 2962 5 4 4 CD cord-022526-j9kg00qf 2962 6 % % NN cord-022526-j9kg00qf 2962 7 to to TO cord-022526-j9kg00qf 2962 8 9 9 CD cord-022526-j9kg00qf 2962 9 % % NN cord-022526-j9kg00qf 2962 10 of of IN cord-022526-j9kg00qf 2962 11 clinically clinically RB cord-022526-j9kg00qf 2962 12 normal normal JJ cord-022526-j9kg00qf 2962 13 foals foal NNS cord-022526-j9kg00qf 2962 14 examined examine VBN cord-022526-j9kg00qf 2962 15 in in IN cord-022526-j9kg00qf 2962 16 endoscopic endoscopic JJ cord-022526-j9kg00qf 2962 17 surveys survey NNS cord-022526-j9kg00qf 2962 18 had have VBD cord-022526-j9kg00qf 2962 19 lesions lesion NNS cord-022526-j9kg00qf 2962 20 observed observe VBN cord-022526-j9kg00qf 2962 21 in in IN cord-022526-j9kg00qf 2962 22 the the DT cord-022526-j9kg00qf 2962 23 gastric gastric JJ cord-022526-j9kg00qf 2962 24 glandular glandular JJ cord-022526-j9kg00qf 2962 25 mucosa mucosa NN cord-022526-j9kg00qf 2962 26 . . . cord-022526-j9kg00qf 2963 1 14 14 CD cord-022526-j9kg00qf 2963 2 , , , cord-022526-j9kg00qf 2963 3 54 54 CD cord-022526-j9kg00qf 2963 4 Critically critically RB cord-022526-j9kg00qf 2963 5 ill ill JJ cord-022526-j9kg00qf 2963 6 neonatal neonatal JJ cord-022526-j9kg00qf 2963 7 foals foal NNS cord-022526-j9kg00qf 2963 8 can can MD cord-022526-j9kg00qf 2963 9 have have VB cord-022526-j9kg00qf 2963 10 a a DT cord-022526-j9kg00qf 2963 11 greatly greatly RB cord-022526-j9kg00qf 2963 12 different different JJ cord-022526-j9kg00qf 2963 13 pH ph NN cord-022526-j9kg00qf 2963 14 profile profile NN cord-022526-j9kg00qf 2963 15 compared compare VBN cord-022526-j9kg00qf 2963 16 with with IN cord-022526-j9kg00qf 2963 17 that that DT cord-022526-j9kg00qf 2963 18 in in IN cord-022526-j9kg00qf 2963 19 clinically clinically RB cord-022526-j9kg00qf 2963 20 normal normal JJ cord-022526-j9kg00qf 2963 21 foals foal NNS cord-022526-j9kg00qf 2963 22 , , , cord-022526-j9kg00qf 2963 23 potentially potentially RB cord-022526-j9kg00qf 2963 24 because because IN cord-022526-j9kg00qf 2963 25 of of IN cord-022526-j9kg00qf 2963 26 alterations alteration NNS cord-022526-j9kg00qf 2963 27 in in IN cord-022526-j9kg00qf 2963 28 gastric gastric JJ cord-022526-j9kg00qf 2963 29 motility motility NN cord-022526-j9kg00qf 2963 30 and and CC cord-022526-j9kg00qf 2963 31 acid acid NN cord-022526-j9kg00qf 2963 32 secretion secretion NN cord-022526-j9kg00qf 2963 33 . . . cord-022526-j9kg00qf 2964 1 31 31 CD cord-022526-j9kg00qf 2964 2 Gastric gastric JJ cord-022526-j9kg00qf 2964 3 ulceration ulceration NN cord-022526-j9kg00qf 2964 4 was be VBD cord-022526-j9kg00qf 2964 5 not not RB cord-022526-j9kg00qf 2964 6 identified identify VBN cord-022526-j9kg00qf 2964 7 in in IN cord-022526-j9kg00qf 2964 8 any any DT cord-022526-j9kg00qf 2964 9 animals animal NNS cord-022526-j9kg00qf 2964 10 at at IN cord-022526-j9kg00qf 2964 11 necropsy necropsy JJ cord-022526-j9kg00qf 2964 12 in in IN cord-022526-j9kg00qf 2964 13 that that DT cord-022526-j9kg00qf 2964 14 study study NN cord-022526-j9kg00qf 2964 15 ; ; : cord-022526-j9kg00qf 2964 16 however however RB cord-022526-j9kg00qf 2964 17 , , , cord-022526-j9kg00qf 2964 18 ulceration ulceration NN cord-022526-j9kg00qf 2964 19 has have VBZ cord-022526-j9kg00qf 2964 20 been be VBN cord-022526-j9kg00qf 2964 21 documented document VBN cord-022526-j9kg00qf 2964 22 in in IN cord-022526-j9kg00qf 2964 23 a a DT cord-022526-j9kg00qf 2964 24 similar similar JJ cord-022526-j9kg00qf 2964 25 population population NN cord-022526-j9kg00qf 2964 26 . . . cord-022526-j9kg00qf 2965 1 12 12 CD cord-022526-j9kg00qf 2966 1 Thus thus RB cord-022526-j9kg00qf 2966 2 factors factor NNS cord-022526-j9kg00qf 2966 3 other other JJ cord-022526-j9kg00qf 2966 4 than than IN cord-022526-j9kg00qf 2966 5 acid acid JJ cord-022526-j9kg00qf 2966 6 exposure exposure NN cord-022526-j9kg00qf 2966 7 , , , cord-022526-j9kg00qf 2966 8 most most RBS cord-022526-j9kg00qf 2966 9 notably notably RB cord-022526-j9kg00qf 2966 10 mucosal mucosal JJ cord-022526-j9kg00qf 2966 11 blood blood NN cord-022526-j9kg00qf 2966 12 flow flow NN cord-022526-j9kg00qf 2966 13 , , , cord-022526-j9kg00qf 2966 14 may may MD cord-022526-j9kg00qf 2966 15 play play VB cord-022526-j9kg00qf 2966 16 an an DT cord-022526-j9kg00qf 2966 17 important important JJ cord-022526-j9kg00qf 2966 18 role role NN cord-022526-j9kg00qf 2966 19 in in IN cord-022526-j9kg00qf 2966 20 the the DT cord-022526-j9kg00qf 2966 21 stressrelated stressrelated JJ cord-022526-j9kg00qf 2966 22 ulceration ulceration NN cord-022526-j9kg00qf 2966 23 in in IN cord-022526-j9kg00qf 2966 24 neonates neonate NNS cord-022526-j9kg00qf 2966 25 . . . cord-022526-j9kg00qf 2967 1 Subjectively subjectively RB cord-022526-j9kg00qf 2967 2 , , , cord-022526-j9kg00qf 2967 3 gastric gastric JJ cord-022526-j9kg00qf 2967 4 ulceration ulceration NN cord-022526-j9kg00qf 2967 5 and and CC cord-022526-j9kg00qf 2967 6 rupture rupture NN cord-022526-j9kg00qf 2967 7 in in IN cord-022526-j9kg00qf 2967 8 the the DT cord-022526-j9kg00qf 2967 9 hospitalized hospitalize VBN cord-022526-j9kg00qf 2967 10 neonatal neonatal JJ cord-022526-j9kg00qf 2967 11 population population NN cord-022526-j9kg00qf 2967 12 occurs occur VBZ cord-022526-j9kg00qf 2967 13 less less RBR cord-022526-j9kg00qf 2967 14 commonly commonly RB cord-022526-j9kg00qf 2967 15 now now RB cord-022526-j9kg00qf 2967 16 than than IN cord-022526-j9kg00qf 2967 17 in in IN cord-022526-j9kg00qf 2967 18 previous previous JJ cord-022526-j9kg00qf 2967 19 reports report NNS cord-022526-j9kg00qf 2967 20 . . . cord-022526-j9kg00qf 2968 1 Advances advance NNS cord-022526-j9kg00qf 2968 2 in in IN cord-022526-j9kg00qf 2968 3 overall overall JJ cord-022526-j9kg00qf 2968 4 neonatal neonatal JJ cord-022526-j9kg00qf 2968 5 care care NN cord-022526-j9kg00qf 2968 6 , , , cord-022526-j9kg00qf 2968 7 especially especially RB cord-022526-j9kg00qf 2968 8 supportive supportive JJ cord-022526-j9kg00qf 2968 9 care care NN cord-022526-j9kg00qf 2968 10 , , , cord-022526-j9kg00qf 2968 11 likely likely RB cord-022526-j9kg00qf 2968 12 have have VBP cord-022526-j9kg00qf 2968 13 contributed contribute VBN cord-022526-j9kg00qf 2968 14 to to IN cord-022526-j9kg00qf 2968 15 this this DT cord-022526-j9kg00qf 2968 16 decline decline NN cord-022526-j9kg00qf 2968 17 . . . cord-022526-j9kg00qf 2969 1 In in IN cord-022526-j9kg00qf 2969 2 suckling suckle VBG cord-022526-j9kg00qf 2969 3 foals foal NNS cord-022526-j9kg00qf 2969 4 less less JJR cord-022526-j9kg00qf 2969 5 than than IN cord-022526-j9kg00qf 2969 6 50 50 CD cord-022526-j9kg00qf 2969 7 days day NNS cord-022526-j9kg00qf 2969 8 old old JJ cord-022526-j9kg00qf 2969 9 , , , cord-022526-j9kg00qf 2969 10 lesions lesion NNS cord-022526-j9kg00qf 2969 11 typically typically RB cord-022526-j9kg00qf 2969 12 originate originate VBP cord-022526-j9kg00qf 2969 13 in in IN cord-022526-j9kg00qf 2969 14 the the DT cord-022526-j9kg00qf 2969 15 squamous squamous JJ cord-022526-j9kg00qf 2969 16 mucosa mucosa NN cord-022526-j9kg00qf 2969 17 adjacent adjacent JJ cord-022526-j9kg00qf 2969 18 to to IN cord-022526-j9kg00qf 2969 19 the the DT cord-022526-j9kg00qf 2969 20 margo margo NNP cord-022526-j9kg00qf 2969 21 plicatus plicatus NNP cord-022526-j9kg00qf 2969 22 along along IN cord-022526-j9kg00qf 2969 23 the the DT cord-022526-j9kg00qf 2969 24 greater great JJR cord-022526-j9kg00qf 2969 25 curvature curvature NN cord-022526-j9kg00qf 2969 26 . . . cord-022526-j9kg00qf 2970 1 Such such JJ cord-022526-j9kg00qf 2970 2 lesions lesion NNS cord-022526-j9kg00qf 2970 3 can can MD cord-022526-j9kg00qf 2970 4 occur occur VB cord-022526-j9kg00qf 2970 5 in in IN cord-022526-j9kg00qf 2970 6 foals foal NNS cord-022526-j9kg00qf 2970 7 as as RB cord-022526-j9kg00qf 2970 8 young young JJ cord-022526-j9kg00qf 2970 9 as as IN cord-022526-j9kg00qf 2970 10 2 2 CD cord-022526-j9kg00qf 2970 11 days day NNS cord-022526-j9kg00qf 2970 12 of of IN cord-022526-j9kg00qf 2970 13 age age NN cord-022526-j9kg00qf 2970 14 and and CC cord-022526-j9kg00qf 2970 15 have have VBP cord-022526-j9kg00qf 2970 16 been be VBN cord-022526-j9kg00qf 2970 17 observed observe VBN cord-022526-j9kg00qf 2970 18 in in IN cord-022526-j9kg00qf 2970 19 50 50 CD cord-022526-j9kg00qf 2970 20 % % NN cord-022526-j9kg00qf 2970 21 of of IN cord-022526-j9kg00qf 2970 22 foals foal NNS cord-022526-j9kg00qf 2970 23 less less JJR cord-022526-j9kg00qf 2970 24 than than IN cord-022526-j9kg00qf 2970 25 50 50 CD cord-022526-j9kg00qf 2970 26 days day NNS cord-022526-j9kg00qf 2970 27 old old JJ cord-022526-j9kg00qf 2970 28 . . . cord-022526-j9kg00qf 2971 1 Histologic Histologic NNP cord-022526-j9kg00qf 2971 2 examination examination NN cord-022526-j9kg00qf 2971 3 of of IN cord-022526-j9kg00qf 2971 4 these these DT cord-022526-j9kg00qf 2971 5 lesions lesion NNS cord-022526-j9kg00qf 2971 6 has have VBZ cord-022526-j9kg00qf 2971 7 revealed reveal VBN cord-022526-j9kg00qf 2971 8 disruption disruption NN cord-022526-j9kg00qf 2971 9 of of IN cord-022526-j9kg00qf 2971 10 the the DT cord-022526-j9kg00qf 2971 11 epithelial epithelial JJ cord-022526-j9kg00qf 2971 12 layers layer NNS cord-022526-j9kg00qf 2971 13 of of IN cord-022526-j9kg00qf 2971 14 the the DT cord-022526-j9kg00qf 2971 15 mucosa mucosa NN cord-022526-j9kg00qf 2971 16 and and CC cord-022526-j9kg00qf 2971 17 a a DT cord-022526-j9kg00qf 2971 18 neutrophilic neutrophilic JJ cord-022526-j9kg00qf 2971 19 infiltration infiltration NN cord-022526-j9kg00qf 2971 20 . . . cord-022526-j9kg00qf 2972 1 Another another DT cord-022526-j9kg00qf 2972 2 phenomenon phenomenon NN cord-022526-j9kg00qf 2972 3 that that WDT cord-022526-j9kg00qf 2972 4 occurs occur VBZ cord-022526-j9kg00qf 2972 5 in in IN cord-022526-j9kg00qf 2972 6 young young JJ cord-022526-j9kg00qf 2972 7 foals foal NNS cord-022526-j9kg00qf 2972 8 is be VBZ cord-022526-j9kg00qf 2972 9 the the DT cord-022526-j9kg00qf 2972 10 shedding shedding NN cord-022526-j9kg00qf 2972 11 , , , cord-022526-j9kg00qf 2972 12 or or CC cord-022526-j9kg00qf 2972 13 desquamation desquamation NN cord-022526-j9kg00qf 2972 14 , , , cord-022526-j9kg00qf 2972 15 of of IN cord-022526-j9kg00qf 2972 16 squamous squamous JJ cord-022526-j9kg00qf 2972 17 epithelium epithelium NN cord-022526-j9kg00qf 2972 18 , , , cord-022526-j9kg00qf 2972 19 which which WDT cord-022526-j9kg00qf 2972 20 appears appear VBZ cord-022526-j9kg00qf 2972 21 as as IN cord-022526-j9kg00qf 2972 22 flakes flake NNS cord-022526-j9kg00qf 2972 23 or or CC cord-022526-j9kg00qf 2972 24 sheets sheet NNS cord-022526-j9kg00qf 2972 25 of of IN cord-022526-j9kg00qf 2972 26 epithelium epithelium NN cord-022526-j9kg00qf 2972 27 . . . cord-022526-j9kg00qf 2973 1 Desquamation desquamation NN cord-022526-j9kg00qf 2973 2 occurs occur VBZ cord-022526-j9kg00qf 2973 3 without without IN cord-022526-j9kg00qf 2973 4 ulceration ulceration NN cord-022526-j9kg00qf 2973 5 in in IN cord-022526-j9kg00qf 2973 6 up up IN cord-022526-j9kg00qf 2973 7 to to TO cord-022526-j9kg00qf 2973 8 80 80 CD cord-022526-j9kg00qf 2973 9 % % NN cord-022526-j9kg00qf 2973 10 of of IN cord-022526-j9kg00qf 2973 11 foals foal NNS cord-022526-j9kg00qf 2973 12 less less JJR cord-022526-j9kg00qf 2973 13 than than IN cord-022526-j9kg00qf 2973 14 35 35 CD cord-022526-j9kg00qf 2973 15 days day NNS cord-022526-j9kg00qf 2973 16 of of IN cord-022526-j9kg00qf 2973 17 age age NN cord-022526-j9kg00qf 2973 18 , , , cord-022526-j9kg00qf 2973 19 and and CC cord-022526-j9kg00qf 2973 20 this this DT cord-022526-j9kg00qf 2973 21 process process NN cord-022526-j9kg00qf 2973 22 typically typically RB cord-022526-j9kg00qf 2973 23 is be VBZ cord-022526-j9kg00qf 2973 24 not not RB cord-022526-j9kg00qf 2973 25 associated associate VBN cord-022526-j9kg00qf 2973 26 with with IN cord-022526-j9kg00qf 2973 27 clinical clinical JJ cord-022526-j9kg00qf 2973 28 signs sign NNS cord-022526-j9kg00qf 2973 29 . . . cord-022526-j9kg00qf 2974 1 13 13 CD cord-022526-j9kg00qf 2974 2 , , , cord-022526-j9kg00qf 2974 3 14 14 CD cord-022526-j9kg00qf 2974 4 , , , cord-022526-j9kg00qf 2974 5 54 54 CD cord-022526-j9kg00qf 2975 1 In in IN cord-022526-j9kg00qf 2975 2 older old JJR cord-022526-j9kg00qf 2975 3 foals foal NNS cord-022526-j9kg00qf 2975 4 , , , cord-022526-j9kg00qf 2975 5 lesions lesion NNS cord-022526-j9kg00qf 2975 6 become become VBP cord-022526-j9kg00qf 2975 7 more more RBR cord-022526-j9kg00qf 2975 8 prevalent prevalent JJ cord-022526-j9kg00qf 2975 9 in in IN cord-022526-j9kg00qf 2975 10 the the DT cord-022526-j9kg00qf 2975 11 squamous squamous JJ cord-022526-j9kg00qf 2975 12 mucosa mucosa NN cord-022526-j9kg00qf 2975 13 , , , cord-022526-j9kg00qf 2975 14 particularly particularly RB cord-022526-j9kg00qf 2975 15 along along IN cord-022526-j9kg00qf 2975 16 the the DT cord-022526-j9kg00qf 2975 17 lesser less JJR cord-022526-j9kg00qf 2975 18 curvature curvature NN cord-022526-j9kg00qf 2975 19 . . . cord-022526-j9kg00qf 2976 1 53 53 CD cord-022526-j9kg00qf 2976 2 Lesions lesion NNS cord-022526-j9kg00qf 2976 3 also also RB cord-022526-j9kg00qf 2976 4 are be VBP cord-022526-j9kg00qf 2976 5 found find VBN cord-022526-j9kg00qf 2976 6 in in IN cord-022526-j9kg00qf 2976 7 the the DT cord-022526-j9kg00qf 2976 8 squamous squamous JJ cord-022526-j9kg00qf 2976 9 mucosa mucosa NN cord-022526-j9kg00qf 2976 10 of of IN cord-022526-j9kg00qf 2976 11 the the DT cord-022526-j9kg00qf 2976 12 fundus fundus NN cord-022526-j9kg00qf 2976 13 and and CC cord-022526-j9kg00qf 2976 14 adjacent adjacent JJ cord-022526-j9kg00qf 2976 15 to to IN cord-022526-j9kg00qf 2976 16 the the DT cord-022526-j9kg00qf 2976 17 margo margo NNP cord-022526-j9kg00qf 2976 18 plicatus plicatus NNP cord-022526-j9kg00qf 2976 19 . . . cord-022526-j9kg00qf 2977 1 These these DT cord-022526-j9kg00qf 2977 2 lesions lesion NNS cord-022526-j9kg00qf 2977 3 can can MD cord-022526-j9kg00qf 2977 4 be be VB cord-022526-j9kg00qf 2977 5 severe severe JJ cord-022526-j9kg00qf 2977 6 and and CC cord-022526-j9kg00qf 2977 7 often often RB cord-022526-j9kg00qf 2977 8 are be VBP cord-022526-j9kg00qf 2977 9 associated associate VBN cord-022526-j9kg00qf 2977 10 with with IN cord-022526-j9kg00qf 2977 11 clinical clinical JJ cord-022526-j9kg00qf 2977 12 signs sign NNS cord-022526-j9kg00qf 2977 13 such such JJ cord-022526-j9kg00qf 2977 14 as as IN cord-022526-j9kg00qf 2977 15 diarrhea diarrhea NN cord-022526-j9kg00qf 2977 16 , , , cord-022526-j9kg00qf 2977 17 poor poor JJ cord-022526-j9kg00qf 2977 18 appetite appetite NN cord-022526-j9kg00qf 2977 19 , , , cord-022526-j9kg00qf 2977 20 and and CC cord-022526-j9kg00qf 2977 21 poor poor JJ cord-022526-j9kg00qf 2977 22 growth growth NN cord-022526-j9kg00qf 2977 23 and and CC cord-022526-j9kg00qf 2977 24 body body NN cord-022526-j9kg00qf 2977 25 condition condition NN cord-022526-j9kg00qf 2977 26 . . . cord-022526-j9kg00qf 2978 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 2978 2 is be VBZ cord-022526-j9kg00qf 2978 3 the the DT cord-022526-j9kg00qf 2978 4 most most RBS cord-022526-j9kg00qf 2978 5 frequent frequent JJ cord-022526-j9kg00qf 2978 6 sign sign NN cord-022526-j9kg00qf 2978 7 in in IN cord-022526-j9kg00qf 2978 8 symptomatic symptomatic JJ cord-022526-j9kg00qf 2978 9 foals foal NNS cord-022526-j9kg00qf 2978 10 with with IN cord-022526-j9kg00qf 2978 11 squamous squamous JJ cord-022526-j9kg00qf 2978 12 mucosal mucosal JJ cord-022526-j9kg00qf 2978 13 lesions lesion NNS cord-022526-j9kg00qf 2978 14 and and CC cord-022526-j9kg00qf 2978 15 is be VBZ cord-022526-j9kg00qf 2978 16 associated associate VBN cord-022526-j9kg00qf 2978 17 with with IN cord-022526-j9kg00qf 2978 18 more more RBR cord-022526-j9kg00qf 2978 19 diffuse diffuse JJ cord-022526-j9kg00qf 2978 20 erosion erosion NN cord-022526-j9kg00qf 2978 21 or or CC cord-022526-j9kg00qf 2978 22 ulceration ulceration NN cord-022526-j9kg00qf 2978 23 of of IN cord-022526-j9kg00qf 2978 24 the the DT cord-022526-j9kg00qf 2978 25 squamous squamous JJ cord-022526-j9kg00qf 2978 26 mucosa mucosa NN cord-022526-j9kg00qf 2978 27 than than IN cord-022526-j9kg00qf 2978 28 that that DT cord-022526-j9kg00qf 2978 29 which which WDT cord-022526-j9kg00qf 2978 30 occurs occur VBZ cord-022526-j9kg00qf 2978 31 in in IN cord-022526-j9kg00qf 2978 32 asymptomatic asymptomatic JJ cord-022526-j9kg00qf 2978 33 foals foal NNS cord-022526-j9kg00qf 2978 34 . . . cord-022526-j9kg00qf 2979 1 In in IN cord-022526-j9kg00qf 2979 2 some some DT cord-022526-j9kg00qf 2979 3 foals foal NNS cord-022526-j9kg00qf 2979 4 , , , cord-022526-j9kg00qf 2979 5 poor poor JJ cord-022526-j9kg00qf 2979 6 growth growth NN cord-022526-j9kg00qf 2979 7 , , , cord-022526-j9kg00qf 2979 8 rough rough JJ cord-022526-j9kg00qf 2979 9 hair hair NN cord-022526-j9kg00qf 2979 10 coat coat NN cord-022526-j9kg00qf 2979 11 , , , cord-022526-j9kg00qf 2979 12 a a DT cord-022526-j9kg00qf 2979 13 potbelly potbelly NN cord-022526-j9kg00qf 2979 14 appearance appearance NN cord-022526-j9kg00qf 2979 15 , , , cord-022526-j9kg00qf 2979 16 or or CC cord-022526-j9kg00qf 2979 17 all all DT cord-022526-j9kg00qf 2979 18 of of IN cord-022526-j9kg00qf 2979 19 those those DT cord-022526-j9kg00qf 2979 20 occur occur VBP cord-022526-j9kg00qf 2979 21 along along IN cord-022526-j9kg00qf 2979 22 with with IN cord-022526-j9kg00qf 2979 23 moderate moderate JJ cord-022526-j9kg00qf 2979 24 to to TO cord-022526-j9kg00qf 2979 25 severe severe JJ cord-022526-j9kg00qf 2979 26 squamous squamous JJ cord-022526-j9kg00qf 2979 27 mucosal mucosal JJ cord-022526-j9kg00qf 2979 28 ulceration ulceration NN cord-022526-j9kg00qf 2979 29 . . . cord-022526-j9kg00qf 2980 1 In in IN cord-022526-j9kg00qf 2980 2 horses horse NNS cord-022526-j9kg00qf 2980 3 with with IN cord-022526-j9kg00qf 2980 4 severe severe JJ cord-022526-j9kg00qf 2980 5 or or CC cord-022526-j9kg00qf 2980 6 diffuse diffuse VB cord-022526-j9kg00qf 2980 7 squamous squamous JJ cord-022526-j9kg00qf 2980 8 ulceration ulceration NN cord-022526-j9kg00qf 2980 9 , , , cord-022526-j9kg00qf 2980 10 bruxism bruxism NN cord-022526-j9kg00qf 2980 11 or or CC cord-022526-j9kg00qf 2980 12 colic colic NN cord-022526-j9kg00qf 2980 13 may may MD cord-022526-j9kg00qf 2980 14 occur occur VB cord-022526-j9kg00qf 2980 15 . . . cord-022526-j9kg00qf 2981 1 Gastroduodenal Gastroduodenal NNP cord-022526-j9kg00qf 2981 2 ulcer ulcer NN cord-022526-j9kg00qf 2981 3 disease disease NN cord-022526-j9kg00qf 2981 4 occurs occur VBZ cord-022526-j9kg00qf 2981 5 almost almost RB cord-022526-j9kg00qf 2981 6 exclusively exclusively RB cord-022526-j9kg00qf 2981 7 in in IN cord-022526-j9kg00qf 2981 8 suckling suckle VBG cord-022526-j9kg00qf 2981 9 and and CC cord-022526-j9kg00qf 2981 10 early early JJ cord-022526-j9kg00qf 2981 11 weanling weanle VBG cord-022526-j9kg00qf 2981 12 foals foal NNS cord-022526-j9kg00qf 2981 13 . . . cord-022526-j9kg00qf 2982 1 Clinical clinical JJ cord-022526-j9kg00qf 2982 2 signs sign NNS cord-022526-j9kg00qf 2982 3 of of IN cord-022526-j9kg00qf 2982 4 duodenal duodenal JJ cord-022526-j9kg00qf 2982 5 ulceration ulceration NN cord-022526-j9kg00qf 2982 6 are be VBP cord-022526-j9kg00qf 2982 7 similar similar JJ cord-022526-j9kg00qf 2982 8 to to IN cord-022526-j9kg00qf 2982 9 those those DT cord-022526-j9kg00qf 2982 10 described describe VBN cord-022526-j9kg00qf 2982 11 for for IN cord-022526-j9kg00qf 2982 12 gastric gastric JJ cord-022526-j9kg00qf 2982 13 ulceration ulceration NN cord-022526-j9kg00qf 2982 14 ( ( -LRB- cord-022526-j9kg00qf 2982 15 bruxism bruxism NN cord-022526-j9kg00qf 2982 16 , , , cord-022526-j9kg00qf 2982 17 colic colic NN cord-022526-j9kg00qf 2982 18 , , , cord-022526-j9kg00qf 2982 19 salivation salivation NN cord-022526-j9kg00qf 2982 20 , , , cord-022526-j9kg00qf 2982 21 diarrhea diarrhea NN cord-022526-j9kg00qf 2982 22 ) ) -RRB- cord-022526-j9kg00qf 2982 23 , , , cord-022526-j9kg00qf 2982 24 but but CC cord-022526-j9kg00qf 2982 25 the the DT cord-022526-j9kg00qf 2982 26 consequences consequence NNS cord-022526-j9kg00qf 2982 27 are be VBP cord-022526-j9kg00qf 2982 28 often often RB cord-022526-j9kg00qf 2982 29 more more RBR cord-022526-j9kg00qf 2982 30 severe severe JJ cord-022526-j9kg00qf 2982 31 . . . cord-022526-j9kg00qf 2983 1 Lesions lesion NNS cord-022526-j9kg00qf 2983 2 occur occur VBP cord-022526-j9kg00qf 2983 3 primarily primarily RB cord-022526-j9kg00qf 2983 4 in in IN cord-022526-j9kg00qf 2983 5 the the DT cord-022526-j9kg00qf 2983 6 proximal proximal JJ cord-022526-j9kg00qf 2983 7 duodenum duodenum NN cord-022526-j9kg00qf 2983 8 and and CC cord-022526-j9kg00qf 2983 9 range range VB cord-022526-j9kg00qf 2983 10 from from IN cord-022526-j9kg00qf 2983 11 diffuse diffuse JJ cord-022526-j9kg00qf 2983 12 inflammation inflammation NN cord-022526-j9kg00qf 2983 13 to to IN cord-022526-j9kg00qf 2983 14 severe severe JJ cord-022526-j9kg00qf 2983 15 ulceration ulceration NN cord-022526-j9kg00qf 2983 16 . . . cord-022526-j9kg00qf 2984 1 Foals foal NNS cord-022526-j9kg00qf 2984 2 with with IN cord-022526-j9kg00qf 2984 3 duodenal duodenal JJ cord-022526-j9kg00qf 2984 4 ulceration ulceration NN cord-022526-j9kg00qf 2984 5 often often RB cord-022526-j9kg00qf 2984 6 have have VBP cord-022526-j9kg00qf 2984 7 delayed delay VBN cord-022526-j9kg00qf 2984 8 gastric gastric JJ cord-022526-j9kg00qf 2984 9 emptying emptying NN cord-022526-j9kg00qf 2984 10 and and CC cord-022526-j9kg00qf 2984 11 may may MD cord-022526-j9kg00qf 2984 12 have have VB cord-022526-j9kg00qf 2984 13 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2984 14 reflux reflux NN cord-022526-j9kg00qf 2984 15 . . . cord-022526-j9kg00qf 2985 1 Complications complication NNS cord-022526-j9kg00qf 2985 2 can can MD cord-022526-j9kg00qf 2985 3 include include VB cord-022526-j9kg00qf 2985 4 gastric gastric JJ cord-022526-j9kg00qf 2985 5 or or CC cord-022526-j9kg00qf 2985 6 duodenal duodenal JJ cord-022526-j9kg00qf 2985 7 rupture rupture NN cord-022526-j9kg00qf 2985 8 , , , cord-022526-j9kg00qf 2985 9 duodenal duodenal JJ cord-022526-j9kg00qf 2985 10 stricture stricture NN cord-022526-j9kg00qf 2985 11 , , , cord-022526-j9kg00qf 2985 12 and and CC cord-022526-j9kg00qf 2985 13 ascending ascend VBG cord-022526-j9kg00qf 2985 14 cholangitis cholangitis NN cord-022526-j9kg00qf 2985 15 . . . cord-022526-j9kg00qf 2986 1 Severe severe JJ cord-022526-j9kg00qf 2986 2 squamous squamous JJ cord-022526-j9kg00qf 2986 3 and and CC cord-022526-j9kg00qf 2986 4 esophageal esophageal JJ cord-022526-j9kg00qf 2986 5 ulceration ulceration NN cord-022526-j9kg00qf 2986 6 and and CC cord-022526-j9kg00qf 2986 7 aspiration aspiration NN cord-022526-j9kg00qf 2986 8 pneumonia pneumonia NN cord-022526-j9kg00qf 2986 9 can can MD cord-022526-j9kg00qf 2986 10 occur occur VB cord-022526-j9kg00qf 2986 11 following follow VBG cord-022526-j9kg00qf 2986 12 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 2986 13 reflux reflux NN cord-022526-j9kg00qf 2986 14 . . . cord-022526-j9kg00qf 2987 1 15 15 CD cord-022526-j9kg00qf 2987 2 , , , cord-022526-j9kg00qf 2987 3 [ [ -LRB- cord-022526-j9kg00qf 2987 4 55 55 CD cord-022526-j9kg00qf 2987 5 ] ] -RRB- cord-022526-j9kg00qf 2987 6 [ [ -LRB- cord-022526-j9kg00qf 2987 7 56 56 CD cord-022526-j9kg00qf 2987 8 ] ] -RRB- cord-022526-j9kg00qf 2987 9 [ [ -LRB- cord-022526-j9kg00qf 2987 10 57 57 CD cord-022526-j9kg00qf 2987 11 ] ] -RRB- cord-022526-j9kg00qf 2987 12 [ [ -LRB- cord-022526-j9kg00qf 2987 13 58 58 CD cord-022526-j9kg00qf 2987 14 ] ] -RRB- cord-022526-j9kg00qf 2988 1 The the DT cord-022526-j9kg00qf 2988 2 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 2988 3 ulcer ulcer NN cord-022526-j9kg00qf 2988 4 disease disease NN cord-022526-j9kg00qf 2988 5 syndrome syndrome NN cord-022526-j9kg00qf 2988 6 can can MD cord-022526-j9kg00qf 2988 7 occur occur VB cord-022526-j9kg00qf 2988 8 in in IN cord-022526-j9kg00qf 2988 9 outbreaks outbreak NNS cord-022526-j9kg00qf 2988 10 and and CC cord-022526-j9kg00qf 2988 11 most most RBS cord-022526-j9kg00qf 2988 12 commonly commonly RB cord-022526-j9kg00qf 2988 13 is be VBZ cord-022526-j9kg00qf 2988 14 identified identify VBN cord-022526-j9kg00qf 2988 15 in in IN cord-022526-j9kg00qf 2988 16 intensive intensive JJ cord-022526-j9kg00qf 2988 17 breeding breeding NN cord-022526-j9kg00qf 2988 18 operations operation NNS cord-022526-j9kg00qf 2988 19 . . . cord-022526-j9kg00qf 2989 1 The the DT cord-022526-j9kg00qf 2989 2 cause cause NN cord-022526-j9kg00qf 2989 3 of of IN cord-022526-j9kg00qf 2989 4 duodenal duodenal JJ cord-022526-j9kg00qf 2989 5 lesions lesion NNS cord-022526-j9kg00qf 2989 6 in in IN cord-022526-j9kg00qf 2989 7 foals foal NNS cord-022526-j9kg00qf 2989 8 is be VBZ cord-022526-j9kg00qf 2989 9 not not RB cord-022526-j9kg00qf 2989 10 known know VBN cord-022526-j9kg00qf 2989 11 . . . cord-022526-j9kg00qf 2990 1 One one CD cord-022526-j9kg00qf 2990 2 theory theory NN cord-022526-j9kg00qf 2990 3 is be VBZ cord-022526-j9kg00qf 2990 4 that that IN cord-022526-j9kg00qf 2990 5 the the DT cord-022526-j9kg00qf 2990 6 problem problem NN cord-022526-j9kg00qf 2990 7 begins begin VBZ cord-022526-j9kg00qf 2990 8 with with IN cord-022526-j9kg00qf 2990 9 diffuse diffuse JJ cord-022526-j9kg00qf 2990 10 duodenal duodenal JJ cord-022526-j9kg00qf 2990 11 inflammation inflammation NN cord-022526-j9kg00qf 2990 12 that that WDT cord-022526-j9kg00qf 2990 13 can can MD cord-022526-j9kg00qf 2990 14 coalesce coalesce VB cord-022526-j9kg00qf 2990 15 down down RP cord-022526-j9kg00qf 2990 16 to to IN cord-022526-j9kg00qf 2990 17 a a DT cord-022526-j9kg00qf 2990 18 focal focal JJ cord-022526-j9kg00qf 2990 19 area area NN cord-022526-j9kg00qf 2990 20 of of IN cord-022526-j9kg00qf 2990 21 ulceration ulceration NN cord-022526-j9kg00qf 2991 1 ( ( -LRB- cord-022526-j9kg00qf 2991 2 G.D. G.D. NNP cord-022526-j9kg00qf 2991 3 Lester Lester NNP cord-022526-j9kg00qf 2991 4 and and CC cord-022526-j9kg00qf 2991 5 A.M. A.M. NNP cord-022526-j9kg00qf 2991 6 Merritt Merritt NNP cord-022526-j9kg00qf 2991 7 , , , cord-022526-j9kg00qf 2991 8 personal personal JJ cord-022526-j9kg00qf 2991 9 communication communication NN cord-022526-j9kg00qf 2991 10 , , , cord-022526-j9kg00qf 2991 11 2002 2002 CD cord-022526-j9kg00qf 2991 12 ) ) -RRB- cord-022526-j9kg00qf 2991 13 . . . cord-022526-j9kg00qf 2992 1 A a DT cord-022526-j9kg00qf 2992 2 temporal temporal JJ cord-022526-j9kg00qf 2992 3 relationship relationship NN cord-022526-j9kg00qf 2992 4 between between IN cord-022526-j9kg00qf 2992 5 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 2992 6 ulcer ulcer NN cord-022526-j9kg00qf 2992 7 disease disease NN cord-022526-j9kg00qf 2992 8 and and CC cord-022526-j9kg00qf 2992 9 rotaviral rotaviral JJ cord-022526-j9kg00qf 2992 10 diarrhea diarrhea NN cord-022526-j9kg00qf 2992 11 has have VBZ cord-022526-j9kg00qf 2992 12 been be VBN cord-022526-j9kg00qf 2992 13 suggested suggest VBN cord-022526-j9kg00qf 2992 14 , , , cord-022526-j9kg00qf 2992 15 but but CC cord-022526-j9kg00qf 2992 16 an an DT cord-022526-j9kg00qf 2992 17 infectious infectious JJ cord-022526-j9kg00qf 2992 18 cause cause NN cord-022526-j9kg00qf 2992 19 remains remain VBZ cord-022526-j9kg00qf 2992 20 unproven unproven JJ cord-022526-j9kg00qf 2992 21 . . . cord-022526-j9kg00qf 2993 1 Although although IN cord-022526-j9kg00qf 2993 2 lesion lesion NN cord-022526-j9kg00qf 2993 3 location location NN cord-022526-j9kg00qf 2993 4 and and CC cord-022526-j9kg00qf 2993 5 severity severity NN cord-022526-j9kg00qf 2993 6 associated associate VBN cord-022526-j9kg00qf 2993 7 with with IN cord-022526-j9kg00qf 2993 8 rotaviral rotaviral JJ cord-022526-j9kg00qf 2993 9 infection infection NN cord-022526-j9kg00qf 2993 10 varies vary VBZ cord-022526-j9kg00qf 2993 11 among among IN cord-022526-j9kg00qf 2993 12 species specie NNS cord-022526-j9kg00qf 2993 13 , , , cord-022526-j9kg00qf 2993 14 duodenal duodenal JJ cord-022526-j9kg00qf 2993 15 ulceration ulceration NN cord-022526-j9kg00qf 2993 16 has have VBZ cord-022526-j9kg00qf 2993 17 not not RB cord-022526-j9kg00qf 2993 18 been be VBN cord-022526-j9kg00qf 2993 19 reported report VBN cord-022526-j9kg00qf 2993 20 . . . cord-022526-j9kg00qf 2994 1 59 59 CD cord-022526-j9kg00qf 2994 2 Clinical clinical JJ cord-022526-j9kg00qf 2994 3 signs sign NNS cord-022526-j9kg00qf 2994 4 attributable attributable JJ cord-022526-j9kg00qf 2994 5 to to IN cord-022526-j9kg00qf 2994 6 EGUS egu NNS cord-022526-j9kg00qf 2994 7 in in IN cord-022526-j9kg00qf 2994 8 older old JJR cord-022526-j9kg00qf 2994 9 horses horse NNS cord-022526-j9kg00qf 2994 10 vary vary VBP cord-022526-j9kg00qf 2994 11 and and CC cord-022526-j9kg00qf 2994 12 classically classically RB cord-022526-j9kg00qf 2994 13 include include VBP cord-022526-j9kg00qf 2994 14 anorexia anorexia NN cord-022526-j9kg00qf 2994 15 and and CC cord-022526-j9kg00qf 2994 16 chronic chronic JJ cord-022526-j9kg00qf 2994 17 or or CC cord-022526-j9kg00qf 2994 18 intermittent intermittent JJ cord-022526-j9kg00qf 2994 19 colic colic NN cord-022526-j9kg00qf 2994 20 of of IN cord-022526-j9kg00qf 2994 21 varying vary VBG cord-022526-j9kg00qf 2994 22 severity severity NN cord-022526-j9kg00qf 2994 23 . . . cord-022526-j9kg00qf 2995 1 60 60 CD cord-022526-j9kg00qf 2995 2 Many many JJ cord-022526-j9kg00qf 2995 3 horses horse NNS cord-022526-j9kg00qf 2995 4 with with IN cord-022526-j9kg00qf 2995 5 endoscopic endoscopic JJ cord-022526-j9kg00qf 2995 6 evidence evidence NN cord-022526-j9kg00qf 2995 7 of of IN cord-022526-j9kg00qf 2995 8 disease disease NN cord-022526-j9kg00qf 2995 9 may may MD cord-022526-j9kg00qf 2995 10 appear appear VB cord-022526-j9kg00qf 2995 11 to to TO cord-022526-j9kg00qf 2995 12 be be VB cord-022526-j9kg00qf 2995 13 clinically clinically RB cord-022526-j9kg00qf 2995 14 normal normal JJ cord-022526-j9kg00qf 2995 15 or or CC cord-022526-j9kg00qf 2995 16 have have VBP cord-022526-j9kg00qf 2995 17 vague vague JJ cord-022526-j9kg00qf 2995 18 signs sign NNS cord-022526-j9kg00qf 2995 19 that that WDT cord-022526-j9kg00qf 2995 20 include include VBP cord-022526-j9kg00qf 2995 21 decreased decrease VBN cord-022526-j9kg00qf 2995 22 consumption consumption NN cord-022526-j9kg00qf 2995 23 of of IN cord-022526-j9kg00qf 2995 24 concentrates concentrate NNS cord-022526-j9kg00qf 2995 25 , , , cord-022526-j9kg00qf 2995 26 postprandial postprandial JJ cord-022526-j9kg00qf 2995 27 episodes episode NNS cord-022526-j9kg00qf 2995 28 of of IN cord-022526-j9kg00qf 2995 29 colic colic NN cord-022526-j9kg00qf 2995 30 , , , cord-022526-j9kg00qf 2995 31 poor poor JJ cord-022526-j9kg00qf 2995 32 performance performance NN cord-022526-j9kg00qf 2995 33 or or CC cord-022526-j9kg00qf 2995 34 failure failure NN cord-022526-j9kg00qf 2995 35 to to TO cord-022526-j9kg00qf 2995 36 train train VB cord-022526-j9kg00qf 2995 37 up up RP cord-022526-j9kg00qf 2995 38 to to IN cord-022526-j9kg00qf 2995 39 expectations expectation NNS cord-022526-j9kg00qf 2995 40 , , , cord-022526-j9kg00qf 2995 41 poorquality poorquality NNP cord-022526-j9kg00qf 2995 42 hair hair NN cord-022526-j9kg00qf 2995 43 coat coat NN cord-022526-j9kg00qf 2995 44 , , , cord-022526-j9kg00qf 2995 45 and and CC cord-022526-j9kg00qf 2995 46 decreased decrease VBD cord-022526-j9kg00qf 2995 47 condition condition NN cord-022526-j9kg00qf 2995 48 or or CC cord-022526-j9kg00qf 2995 49 failure failure NN cord-022526-j9kg00qf 2995 50 to to TO cord-022526-j9kg00qf 2995 51 thrive thrive VB cord-022526-j9kg00qf 2995 52 . . . cord-022526-j9kg00qf 2996 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 2996 2 typically typically RB cord-022526-j9kg00qf 2996 3 is be VBZ cord-022526-j9kg00qf 2996 4 not not RB cord-022526-j9kg00qf 2996 5 associated associate VBN cord-022526-j9kg00qf 2996 6 with with IN cord-022526-j9kg00qf 2996 7 gastric gastric JJ cord-022526-j9kg00qf 2996 8 ulceration ulceration NN cord-022526-j9kg00qf 2996 9 in in IN cord-022526-j9kg00qf 2996 10 adult adult NN cord-022526-j9kg00qf 2996 11 horses horse NNS cord-022526-j9kg00qf 2996 12 , , , cord-022526-j9kg00qf 2996 13 although although IN cord-022526-j9kg00qf 2996 14 ulceration ulceration NN cord-022526-j9kg00qf 2996 15 can can MD cord-022526-j9kg00qf 2996 16 occur occur VB cord-022526-j9kg00qf 2996 17 concurrently concurrently RB cord-022526-j9kg00qf 2996 18 with with IN cord-022526-j9kg00qf 2996 19 other other JJ cord-022526-j9kg00qf 2996 20 causes cause NNS cord-022526-j9kg00qf 2996 21 of of IN cord-022526-j9kg00qf 2996 22 diarrhea diarrhea NN cord-022526-j9kg00qf 2996 23 . . . cord-022526-j9kg00qf 2997 1 Horses horse NNS cord-022526-j9kg00qf 2997 2 actively actively RB cord-022526-j9kg00qf 2997 3 racing race VBG cord-022526-j9kg00qf 2997 4 are be VBP cord-022526-j9kg00qf 2997 5 more more RBR cord-022526-j9kg00qf 2997 6 likely likely JJ cord-022526-j9kg00qf 2997 7 to to TO cord-022526-j9kg00qf 2997 8 have have VB cord-022526-j9kg00qf 2997 9 squamous squamous JJ cord-022526-j9kg00qf 2997 10 ulceration ulceration NN cord-022526-j9kg00qf 2997 11 than than IN cord-022526-j9kg00qf 2997 12 those those DT cord-022526-j9kg00qf 2997 13 solely solely RB cord-022526-j9kg00qf 2997 14 in in IN cord-022526-j9kg00qf 2997 15 training training NN cord-022526-j9kg00qf 2997 16 . . . cord-022526-j9kg00qf 2998 1 4 4 LS cord-022526-j9kg00qf 2998 2 Lesions lesion NNS cord-022526-j9kg00qf 2998 3 occur occur VBP cord-022526-j9kg00qf 2998 4 predominantly predominantly RB cord-022526-j9kg00qf 2998 5 in in IN cord-022526-j9kg00qf 2998 6 the the DT cord-022526-j9kg00qf 2998 7 squamous squamous JJ cord-022526-j9kg00qf 2998 8 mucosa mucosa NN cord-022526-j9kg00qf 2998 9 , , , cord-022526-j9kg00qf 2998 10 particularly particularly RB cord-022526-j9kg00qf 2998 11 adjacent adjacent JJ cord-022526-j9kg00qf 2998 12 to to IN cord-022526-j9kg00qf 2998 13 the the DT cord-022526-j9kg00qf 2998 14 margo margo NNP cord-022526-j9kg00qf 2998 15 plicatus plicatus NNP cord-022526-j9kg00qf 2999 1 ( ( -LRB- cord-022526-j9kg00qf 2999 2 Figure figure NN cord-022526-j9kg00qf 2999 3 13.10 13.10 CD cord-022526-j9kg00qf 2999 4 - - SYM cord-022526-j9kg00qf 2999 5 1 1 CD cord-022526-j9kg00qf 2999 6 ) ) -RRB- cord-022526-j9kg00qf 2999 7 . . . cord-022526-j9kg00qf 3000 1 In in IN cord-022526-j9kg00qf 3000 2 more more JJR cord-022526-j9kg00qf 3000 3 severe severe JJ cord-022526-j9kg00qf 3000 4 cases case NNS cord-022526-j9kg00qf 3000 5 , , , cord-022526-j9kg00qf 3000 6 lesions lesion NNS cord-022526-j9kg00qf 3000 7 can can MD cord-022526-j9kg00qf 3000 8 extend extend VB cord-022526-j9kg00qf 3000 9 dorsally dorsally RB cord-022526-j9kg00qf 3000 10 into into IN cord-022526-j9kg00qf 3000 11 the the DT cord-022526-j9kg00qf 3000 12 squamous squamous JJ cord-022526-j9kg00qf 3000 13 fundus fundus NN cord-022526-j9kg00qf 3000 14 . . . cord-022526-j9kg00qf 3001 1 Clinically clinically RB cord-022526-j9kg00qf 3001 2 relevant relevant JJ cord-022526-j9kg00qf 3001 3 lesions lesion NNS cord-022526-j9kg00qf 3001 4 typically typically RB cord-022526-j9kg00qf 3001 5 affect affect VBP cord-022526-j9kg00qf 3001 6 a a DT cord-022526-j9kg00qf 3001 7 greater great JJR cord-022526-j9kg00qf 3001 8 portion portion NN cord-022526-j9kg00qf 3001 9 of of IN cord-022526-j9kg00qf 3001 10 the the DT cord-022526-j9kg00qf 3001 11 squamous squamous JJ cord-022526-j9kg00qf 3001 12 mucosa mucosa NN cord-022526-j9kg00qf 3001 13 and and CC cord-022526-j9kg00qf 3001 14 can can MD cord-022526-j9kg00qf 3001 15 be be VB cord-022526-j9kg00qf 3001 16 deep deep JJ cord-022526-j9kg00qf 3001 17 enough enough RB cord-022526-j9kg00qf 3001 18 to to TO cord-022526-j9kg00qf 3001 19 cause cause VB cord-022526-j9kg00qf 3001 20 bleeding bleed VBG cord-022526-j9kg00qf 3001 21 . . . cord-022526-j9kg00qf 3002 1 However however RB cord-022526-j9kg00qf 3002 2 , , , cord-022526-j9kg00qf 3002 3 bleeding bleed VBG cord-022526-j9kg00qf 3002 4 from from IN cord-022526-j9kg00qf 3002 5 ulcers ulcer NNS cord-022526-j9kg00qf 3002 6 in in IN cord-022526-j9kg00qf 3002 7 the the DT cord-022526-j9kg00qf 3002 8 gastric gastric JJ cord-022526-j9kg00qf 3002 9 squamous squamous JJ cord-022526-j9kg00qf 3002 10 mucosa mucosa NN cord-022526-j9kg00qf 3002 11 typically typically RB cord-022526-j9kg00qf 3002 12 is be VBZ cord-022526-j9kg00qf 3002 13 not not RB cord-022526-j9kg00qf 3002 14 associated associate VBN cord-022526-j9kg00qf 3002 15 with with IN cord-022526-j9kg00qf 3002 16 anemia anemia NN cord-022526-j9kg00qf 3002 17 or or CC cord-022526-j9kg00qf 3002 18 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 3002 19 . . . cord-022526-j9kg00qf 3003 1 According accord VBG cord-022526-j9kg00qf 3003 2 to to IN cord-022526-j9kg00qf 3003 3 a a DT cord-022526-j9kg00qf 3003 4 recent recent JJ cord-022526-j9kg00qf 3003 5 study study NN cord-022526-j9kg00qf 3003 6 , , , cord-022526-j9kg00qf 3003 7 the the DT cord-022526-j9kg00qf 3003 8 incidence incidence NN cord-022526-j9kg00qf 3003 9 of of IN cord-022526-j9kg00qf 3003 10 glandular glandular JJ cord-022526-j9kg00qf 3003 11 lesions lesion NNS cord-022526-j9kg00qf 3003 12 , , , cord-022526-j9kg00qf 3003 13 particularly particularly RB cord-022526-j9kg00qf 3003 14 within within IN cord-022526-j9kg00qf 3003 15 the the DT cord-022526-j9kg00qf 3003 16 pyloric pyloric JJ cord-022526-j9kg00qf 3003 17 region region NN cord-022526-j9kg00qf 3003 18 , , , cord-022526-j9kg00qf 3003 19 may may MD cord-022526-j9kg00qf 3003 20 be be VB cord-022526-j9kg00qf 3003 21 higher high JJR cord-022526-j9kg00qf 3003 22 than than IN cord-022526-j9kg00qf 3003 23 previously previously RB cord-022526-j9kg00qf 3003 24 reported report VBN cord-022526-j9kg00qf 3003 25 , , , cord-022526-j9kg00qf 3003 26 11 11 CD cord-022526-j9kg00qf 3003 27 which which WDT cord-022526-j9kg00qf 3003 28 emphasizes emphasize VBZ cord-022526-j9kg00qf 3003 29 the the DT cord-022526-j9kg00qf 3003 30 importance importance NN cord-022526-j9kg00qf 3003 31 of of IN cord-022526-j9kg00qf 3003 32 a a DT cord-022526-j9kg00qf 3003 33 thorough thorough JJ cord-022526-j9kg00qf 3003 34 endoscopic endoscopic JJ cord-022526-j9kg00qf 3003 35 examination examination NN cord-022526-j9kg00qf 3003 36 and and CC cord-022526-j9kg00qf 3003 37 proper proper JJ cord-022526-j9kg00qf 3003 38 documentation documentation NN cord-022526-j9kg00qf 3003 39 of of IN cord-022526-j9kg00qf 3003 40 lesion lesion NN cord-022526-j9kg00qf 3003 41 location location NN cord-022526-j9kg00qf 3003 42 when when WRB cord-022526-j9kg00qf 3003 43 reporting report VBG cord-022526-j9kg00qf 3003 44 or or CC cord-022526-j9kg00qf 3003 45 discussing discuss VBG cord-022526-j9kg00qf 3003 46 EGUS EGUS NNP cord-022526-j9kg00qf 3003 47 , , , cord-022526-j9kg00qf 3003 48 especially especially RB cord-022526-j9kg00qf 3003 49 the the DT cord-022526-j9kg00qf 3003 50 differentiation differentiation NN cord-022526-j9kg00qf 3003 51 between between IN cord-022526-j9kg00qf 3003 52 squamous squamous JJ cord-022526-j9kg00qf 3003 53 and and CC cord-022526-j9kg00qf 3003 54 glandular glandular JJ cord-022526-j9kg00qf 3003 55 disease disease NN cord-022526-j9kg00qf 3003 56 . . . cord-022526-j9kg00qf 3003 57 _SP cord-022526-j9kg00qf 3004 1 Although although IN cord-022526-j9kg00qf 3004 2 one one PRP cord-022526-j9kg00qf 3004 3 may may MD cord-022526-j9kg00qf 3004 4 suspect suspect VB cord-022526-j9kg00qf 3004 5 a a DT cord-022526-j9kg00qf 3004 6 diagnosis diagnosis NN cord-022526-j9kg00qf 3004 7 of of IN cord-022526-j9kg00qf 3004 8 EGUS egu NNS cord-022526-j9kg00qf 3004 9 based base VBN cord-022526-j9kg00qf 3004 10 on on IN cord-022526-j9kg00qf 3004 11 clinical clinical JJ cord-022526-j9kg00qf 3004 12 signs sign NNS cord-022526-j9kg00qf 3004 13 and and CC cord-022526-j9kg00qf 3004 14 response response NN cord-022526-j9kg00qf 3004 15 to to IN cord-022526-j9kg00qf 3004 16 treatment treatment NN cord-022526-j9kg00qf 3004 17 , , , cord-022526-j9kg00qf 3004 18 the the DT cord-022526-j9kg00qf 3004 19 only only JJ cord-022526-j9kg00qf 3004 20 current current JJ cord-022526-j9kg00qf 3004 21 method method NN cord-022526-j9kg00qf 3004 22 of of IN cord-022526-j9kg00qf 3004 23 confirmation confirmation NN cord-022526-j9kg00qf 3004 24 is be VBZ cord-022526-j9kg00qf 3004 25 via via IN cord-022526-j9kg00qf 3004 26 gastroendoscopy gastroendoscopy NNP cord-022526-j9kg00qf 3004 27 , , , cord-022526-j9kg00qf 3004 28 which which WDT cord-022526-j9kg00qf 3004 29 one one PRP cord-022526-j9kg00qf 3004 30 can can MD cord-022526-j9kg00qf 3004 31 perform perform VB cord-022526-j9kg00qf 3004 32 easily easily RB cord-022526-j9kg00qf 3004 33 in in IN cord-022526-j9kg00qf 3004 34 the the DT cord-022526-j9kg00qf 3004 35 standing standing JJ cord-022526-j9kg00qf 3004 36 horse horse NN cord-022526-j9kg00qf 3004 37 or or CC cord-022526-j9kg00qf 3004 38 foal foal NN cord-022526-j9kg00qf 3004 39 with with IN cord-022526-j9kg00qf 3004 40 mild mild JJ cord-022526-j9kg00qf 3004 41 sedation sedation NN cord-022526-j9kg00qf 3004 42 . . . cord-022526-j9kg00qf 3005 1 In in IN cord-022526-j9kg00qf 3005 2 adult adult NN cord-022526-j9kg00qf 3005 3 horses horse NNS cord-022526-j9kg00qf 3005 4 a a DT cord-022526-j9kg00qf 3005 5 3-m 3-m CD cord-022526-j9kg00qf 3005 6 endoscope endoscope NN cord-022526-j9kg00qf 3005 7 allows allow VBZ cord-022526-j9kg00qf 3005 8 for for IN cord-022526-j9kg00qf 3005 9 visual visual JJ cord-022526-j9kg00qf 3005 10 inspection inspection NN cord-022526-j9kg00qf 3005 11 of of IN cord-022526-j9kg00qf 3005 12 the the DT cord-022526-j9kg00qf 3005 13 entire entire JJ cord-022526-j9kg00qf 3005 14 stomach stomach NN cord-022526-j9kg00qf 3005 15 , , , cord-022526-j9kg00qf 3005 16 pylorus pylorus NN cord-022526-j9kg00qf 3005 17 , , , cord-022526-j9kg00qf 3005 18 and and CC cord-022526-j9kg00qf 3005 19 proximal proximal JJ cord-022526-j9kg00qf 3005 20 duodenum duodenum NN cord-022526-j9kg00qf 3005 21 . . . cord-022526-j9kg00qf 3006 1 Shorter short JJR cord-022526-j9kg00qf 3006 2 scopes scope NNS cord-022526-j9kg00qf 3006 3 permit permit VBP cord-022526-j9kg00qf 3006 4 examination examination NN cord-022526-j9kg00qf 3006 5 of of IN cord-022526-j9kg00qf 3006 6 the the DT cord-022526-j9kg00qf 3006 7 gastric gastric JJ cord-022526-j9kg00qf 3006 8 body body NN cord-022526-j9kg00qf 3006 9 and and CC cord-022526-j9kg00qf 3006 10 fundus fundus NN cord-022526-j9kg00qf 3006 11 , , , cord-022526-j9kg00qf 3006 12 but but CC cord-022526-j9kg00qf 3006 13 not not RB cord-022526-j9kg00qf 3006 14 the the DT cord-022526-j9kg00qf 3006 15 pyloric pyloric JJ cord-022526-j9kg00qf 3006 16 antrum antrum NN cord-022526-j9kg00qf 3006 17 in in IN cord-022526-j9kg00qf 3006 18 most most JJS cord-022526-j9kg00qf 3006 19 cases case NNS cord-022526-j9kg00qf 3006 20 . . . cord-022526-j9kg00qf 3007 1 One one PRP cord-022526-j9kg00qf 3007 2 should should MD cord-022526-j9kg00qf 3007 3 use use VB cord-022526-j9kg00qf 3007 4 an an DT cord-022526-j9kg00qf 3007 5 endoscope endoscope NN cord-022526-j9kg00qf 3007 6 with with IN cord-022526-j9kg00qf 3007 7 a a DT cord-022526-j9kg00qf 3007 8 maximum maximum JJ cord-022526-j9kg00qf 3007 9 external external JJ cord-022526-j9kg00qf 3007 10 diameter diameter NN cord-022526-j9kg00qf 3007 11 of of IN cord-022526-j9kg00qf 3007 12 9 9 CD cord-022526-j9kg00qf 3007 13 mm mm NNS cord-022526-j9kg00qf 3007 14 for for IN cord-022526-j9kg00qf 3007 15 neonatal neonatal JJ cord-022526-j9kg00qf 3007 16 foals foal NNS cord-022526-j9kg00qf 3007 17 . . . cord-022526-j9kg00qf 3008 1 Numerous numerous JJ cord-022526-j9kg00qf 3008 2 scoring score VBG cord-022526-j9kg00qf 3008 3 systems system NNS cord-022526-j9kg00qf 3008 4 for for IN cord-022526-j9kg00qf 3008 5 lesion lesion NN cord-022526-j9kg00qf 3008 6 severity severity NN cord-022526-j9kg00qf 3008 7 have have VBP cord-022526-j9kg00qf 3008 8 been be VBN cord-022526-j9kg00qf 3008 9 described describe VBN cord-022526-j9kg00qf 3008 10 , , , cord-022526-j9kg00qf 3008 11 but but CC cord-022526-j9kg00qf 3008 12 a a DT cord-022526-j9kg00qf 3008 13 recent recent JJ cord-022526-j9kg00qf 3008 14 consensus consensus NN cord-022526-j9kg00qf 3008 15 has have VBZ cord-022526-j9kg00qf 3008 16 been be VBN cord-022526-j9kg00qf 3008 17 published publish VBN cord-022526-j9kg00qf 3008 18 by by IN cord-022526-j9kg00qf 3008 19 the the DT cord-022526-j9kg00qf 3008 20 Equine Equine NNP cord-022526-j9kg00qf 3008 21 Gastric Gastric NNP cord-022526-j9kg00qf 3008 22 Ulcer Ulcer NNP cord-022526-j9kg00qf 3008 23 Council Council NNP cord-022526-j9kg00qf 3008 24 ( ( -LRB- cord-022526-j9kg00qf 3008 25 Table Table NNP cord-022526-j9kg00qf 3008 26 13 13 CD cord-022526-j9kg00qf 3008 27 .10 .10 CD cord-022526-j9kg00qf 3008 28 - - SYM cord-022526-j9kg00qf 3008 29 1 1 CD cord-022526-j9kg00qf 3008 30 ) ) -RRB- cord-022526-j9kg00qf 3008 31 . . . cord-022526-j9kg00qf 3009 1 2 2 CD cord-022526-j9kg00qf 3009 2 Duodenal duodenal JJ cord-022526-j9kg00qf 3009 3 ulceration ulceration NN cord-022526-j9kg00qf 3009 4 can can MD cord-022526-j9kg00qf 3009 5 be be VB cord-022526-j9kg00qf 3009 6 difficult difficult JJ cord-022526-j9kg00qf 3009 7 to to TO cord-022526-j9kg00qf 3009 8 confirm confirm VB cord-022526-j9kg00qf 3009 9 . . . cord-022526-j9kg00qf 3010 1 Duodenoscopy Duodenoscopy NNP cord-022526-j9kg00qf 3010 2 is be VBZ cord-022526-j9kg00qf 3010 3 the the DT cord-022526-j9kg00qf 3010 4 most most RBS cord-022526-j9kg00qf 3010 5 specific specific JJ cord-022526-j9kg00qf 3010 6 means mean NNS cord-022526-j9kg00qf 3010 7 of of IN cord-022526-j9kg00qf 3010 8 diagnosis diagnosis NN cord-022526-j9kg00qf 3010 9 , , , cord-022526-j9kg00qf 3010 10 although although IN cord-022526-j9kg00qf 3010 11 the the DT cord-022526-j9kg00qf 3010 12 procedure procedure NN cord-022526-j9kg00qf 3010 13 is be VBZ cord-022526-j9kg00qf 3010 14 more more RBR cord-022526-j9kg00qf 3010 15 difficult difficult JJ cord-022526-j9kg00qf 3010 16 than than IN cord-022526-j9kg00qf 3010 17 gastroscopy gastroscopy JJ cord-022526-j9kg00qf 3010 18 . . . cord-022526-j9kg00qf 3011 1 Additionally additionally RB cord-022526-j9kg00qf 3011 2 , , , cord-022526-j9kg00qf 3011 3 an an DT cord-022526-j9kg00qf 3011 4 endoscope endoscope NN cord-022526-j9kg00qf 3011 5 at at RB cord-022526-j9kg00qf 3011 6 least least RBS cord-022526-j9kg00qf 3011 7 200 200 CD cord-022526-j9kg00qf 3011 8 cm cm NNS cord-022526-j9kg00qf 3011 9 in in IN cord-022526-j9kg00qf 3011 10 length length NN cord-022526-j9kg00qf 3011 11 is be VBZ cord-022526-j9kg00qf 3011 12 needed need VBN cord-022526-j9kg00qf 3011 13 for for IN cord-022526-j9kg00qf 3011 14 foals foal NNS cord-022526-j9kg00qf 3011 15 up up IN cord-022526-j9kg00qf 3011 16 to to IN cord-022526-j9kg00qf 3011 17 5 5 CD cord-022526-j9kg00qf 3011 18 to to TO cord-022526-j9kg00qf 3011 19 7 7 CD cord-022526-j9kg00qf 3011 20 months month NNS cord-022526-j9kg00qf 3011 21 old old JJ cord-022526-j9kg00qf 3011 22 , , , cord-022526-j9kg00qf 3011 23 and and CC cord-022526-j9kg00qf 3011 24 a a DT cord-022526-j9kg00qf 3011 25 longer long JJR cord-022526-j9kg00qf 3011 26 endoscope endoscope NN cord-022526-j9kg00qf 3011 27 usually usually RB cord-022526-j9kg00qf 3011 28 is be VBZ cord-022526-j9kg00qf 3011 29 required require VBN cord-022526-j9kg00qf 3011 30 for for IN cord-022526-j9kg00qf 3011 31 older old JJR cord-022526-j9kg00qf 3011 32 animals animal NNS cord-022526-j9kg00qf 3011 33 . . . cord-022526-j9kg00qf 3012 1 Diffuse diffuse VB cord-022526-j9kg00qf 3012 2 reddening reddening NN cord-022526-j9kg00qf 3012 3 or or CC cord-022526-j9kg00qf 3012 4 inflammation inflammation NN cord-022526-j9kg00qf 3012 5 may may MD cord-022526-j9kg00qf 3012 6 be be VB cord-022526-j9kg00qf 3012 7 the the DT cord-022526-j9kg00qf 3012 8 only only JJ cord-022526-j9kg00qf 3012 9 recognizable recognizable JJ cord-022526-j9kg00qf 3012 10 lesion lesion NN cord-022526-j9kg00qf 3012 11 in in IN cord-022526-j9kg00qf 3012 12 cases case NNS cord-022526-j9kg00qf 3012 13 of of IN cord-022526-j9kg00qf 3012 14 early early JJ cord-022526-j9kg00qf 3012 15 duodenal duodenal JJ cord-022526-j9kg00qf 3012 16 disease disease NN cord-022526-j9kg00qf 3012 17 . . . cord-022526-j9kg00qf 3013 1 Excessive excessive JJ cord-022526-j9kg00qf 3013 2 enterogastric enterogastric JJ cord-022526-j9kg00qf 3013 3 reflux reflux NN cord-022526-j9kg00qf 3013 4 of of IN cord-022526-j9kg00qf 3013 5 bile bile NN cord-022526-j9kg00qf 3013 6 through through IN cord-022526-j9kg00qf 3013 7 the the DT cord-022526-j9kg00qf 3013 8 pylorus pylorus NN cord-022526-j9kg00qf 3013 9 suggests suggest VBZ cord-022526-j9kg00qf 3013 10 duodenal duodenal JJ cord-022526-j9kg00qf 3013 11 dysfunction dysfunction NN cord-022526-j9kg00qf 3013 12 . . . cord-022526-j9kg00qf 3014 1 However however RB cord-022526-j9kg00qf 3014 2 , , , cord-022526-j9kg00qf 3014 3 the the DT cord-022526-j9kg00qf 3014 4 pylorus pylorus NN cord-022526-j9kg00qf 3014 5 frequently frequently RB cord-022526-j9kg00qf 3014 6 appears appear VBZ cord-022526-j9kg00qf 3014 7 open open JJ cord-022526-j9kg00qf 3014 8 , , , cord-022526-j9kg00qf 3014 9 and and CC cord-022526-j9kg00qf 3014 10 some some DT cord-022526-j9kg00qf 3014 11 degree degree NN cord-022526-j9kg00qf 3014 12 of of IN cord-022526-j9kg00qf 3014 13 enterogastric enterogastric JJ cord-022526-j9kg00qf 3014 14 reflux reflux NN cord-022526-j9kg00qf 3014 15 is be VBZ cord-022526-j9kg00qf 3014 16 common common JJ cord-022526-j9kg00qf 3014 17 under under IN cord-022526-j9kg00qf 3014 18 normal normal JJ cord-022526-j9kg00qf 3014 19 conditions condition NNS cord-022526-j9kg00qf 3014 20 . . . cord-022526-j9kg00qf 3015 1 Ulceration ulceration NN cord-022526-j9kg00qf 3015 2 at at IN cord-022526-j9kg00qf 3015 3 the the DT cord-022526-j9kg00qf 3015 4 pylorus pylorus JJ cord-022526-j9kg00qf 3015 5 or or CC cord-022526-j9kg00qf 3015 6 pyloric pyloric JJ cord-022526-j9kg00qf 3015 7 antrum antrum NN cord-022526-j9kg00qf 3015 8 also also RB cord-022526-j9kg00qf 3015 9 suggests suggest VBZ cord-022526-j9kg00qf 3015 10 the the DT cord-022526-j9kg00qf 3015 11 presence presence NN cord-022526-j9kg00qf 3015 12 of of IN cord-022526-j9kg00qf 3015 13 a a DT cord-022526-j9kg00qf 3015 14 duodenal duodenal JJ cord-022526-j9kg00qf 3015 15 lesion lesion NN cord-022526-j9kg00qf 3015 16 . . . cord-022526-j9kg00qf 3016 1 If if IN cord-022526-j9kg00qf 3016 2 one one PRP cord-022526-j9kg00qf 3016 3 can can MD cord-022526-j9kg00qf 3016 4 perform perform VB cord-022526-j9kg00qf 3016 5 gastroendoscopy gastroendoscopy NN cord-022526-j9kg00qf 3016 6 , , , cord-022526-j9kg00qf 3016 7 but but CC cord-022526-j9kg00qf 3016 8 not not RB cord-022526-j9kg00qf 3016 9 duodenoscopy duodenoscopy JJ cord-022526-j9kg00qf 3016 10 , , , cord-022526-j9kg00qf 3016 11 the the DT cord-022526-j9kg00qf 3016 12 severity severity NN cord-022526-j9kg00qf 3016 13 of of IN cord-022526-j9kg00qf 3016 14 lesions lesion NNS cord-022526-j9kg00qf 3016 15 , , , cord-022526-j9kg00qf 3016 16 particularly particularly RB cord-022526-j9kg00qf 3016 17 in in IN cord-022526-j9kg00qf 3016 18 the the DT cord-022526-j9kg00qf 3016 19 glandular glandular JJ cord-022526-j9kg00qf 3016 20 mucosa mucosa NN cord-022526-j9kg00qf 3016 21 and and CC cord-022526-j9kg00qf 3016 22 in in IN cord-022526-j9kg00qf 3016 23 the the DT cord-022526-j9kg00qf 3016 24 squamous squamous JJ cord-022526-j9kg00qf 3016 25 mucosa mucosa NN cord-022526-j9kg00qf 3016 26 of of IN cord-022526-j9kg00qf 3016 27 the the DT cord-022526-j9kg00qf 3016 28 lesser less JJR cord-022526-j9kg00qf 3016 29 curvature curvature NN cord-022526-j9kg00qf 3016 30 dorsal dorsal JJ cord-022526-j9kg00qf 3016 31 to to IN cord-022526-j9kg00qf 3016 32 the the DT cord-022526-j9kg00qf 3016 33 pyloric pyloric JJ cord-022526-j9kg00qf 3016 34 antrum antrum NN cord-022526-j9kg00qf 3016 35 , , , cord-022526-j9kg00qf 3016 36 usually usually RB cord-022526-j9kg00qf 3016 37 will will MD cord-022526-j9kg00qf 3016 38 be be VB cord-022526-j9kg00qf 3016 39 severe severe JJ cord-022526-j9kg00qf 3016 40 when when WRB cord-022526-j9kg00qf 3016 41 duodenal duodenal JJ cord-022526-j9kg00qf 3016 42 ulcers ulcer NNS cord-022526-j9kg00qf 3016 43 are be VBP cord-022526-j9kg00qf 3016 44 present present JJ cord-022526-j9kg00qf 3016 45 . . . cord-022526-j9kg00qf 3017 1 Multiple multiple JJ cord-022526-j9kg00qf 3017 2 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 3017 3 treatments treatment NNS cord-022526-j9kg00qf 3017 4 have have VBP cord-022526-j9kg00qf 3017 5 been be VBN cord-022526-j9kg00qf 3017 6 suggested suggest VBN cord-022526-j9kg00qf 3017 7 for for IN cord-022526-j9kg00qf 3017 8 treating treat VBG cord-022526-j9kg00qf 3017 9 EGUS egu NNS cord-022526-j9kg00qf 3017 10 . . . cord-022526-j9kg00qf 3018 1 Because because IN cord-022526-j9kg00qf 3018 2 acid acid NN cord-022526-j9kg00qf 3018 3 has have VBZ cord-022526-j9kg00qf 3018 4 been be VBN cord-022526-j9kg00qf 3018 5 implicated implicate VBN cord-022526-j9kg00qf 3018 6 as as IN cord-022526-j9kg00qf 3018 7 the the DT cord-022526-j9kg00qf 3018 8 most most RBS cord-022526-j9kg00qf 3018 9 important important JJ cord-022526-j9kg00qf 3018 10 pathophysiologic pathophysiologic NN cord-022526-j9kg00qf 3018 11 component component NN cord-022526-j9kg00qf 3018 12 of of IN cord-022526-j9kg00qf 3018 13 squamous squamous JJ cord-022526-j9kg00qf 3018 14 ulcer ulcer NN cord-022526-j9kg00qf 3018 15 disease disease NN cord-022526-j9kg00qf 3018 16 , , , cord-022526-j9kg00qf 3018 17 most most JJS cord-022526-j9kg00qf 3018 18 antiulcer antiulcer NNP cord-022526-j9kg00qf 3018 19 therapy therapy NN cord-022526-j9kg00qf 3018 20 centers center NNS cord-022526-j9kg00qf 3018 21 on on IN cord-022526-j9kg00qf 3018 22 suppression suppression NN cord-022526-j9kg00qf 3018 23 or or CC cord-022526-j9kg00qf 3018 24 neutralization neutralization NN cord-022526-j9kg00qf 3018 25 of of IN cord-022526-j9kg00qf 3018 26 gastric gastric JJ cord-022526-j9kg00qf 3018 27 acid acid NN cord-022526-j9kg00qf 3018 28 . . . cord-022526-j9kg00qf 3019 1 Severity severity NN cord-022526-j9kg00qf 3019 2 and and CC cord-022526-j9kg00qf 3019 3 location location NN cord-022526-j9kg00qf 3019 4 of of IN cord-022526-j9kg00qf 3019 5 gastric gastric JJ cord-022526-j9kg00qf 3019 6 lesions lesion NNS cord-022526-j9kg00qf 3019 7 and and CC cord-022526-j9kg00qf 3019 8 severity severity NN cord-022526-j9kg00qf 3019 9 and and CC cord-022526-j9kg00qf 3019 10 duration duration NN cord-022526-j9kg00qf 3019 11 of of IN cord-022526-j9kg00qf 3019 12 clinical clinical JJ cord-022526-j9kg00qf 3019 13 signs sign NNS cord-022526-j9kg00qf 3019 14 , , , cord-022526-j9kg00qf 3019 15 as as RB cord-022526-j9kg00qf 3019 16 well well RB cord-022526-j9kg00qf 3019 17 as as IN cord-022526-j9kg00qf 3019 18 medication medication NN cord-022526-j9kg00qf 3019 19 cost cost NN cord-022526-j9kg00qf 3019 20 , , , cord-022526-j9kg00qf 3019 21 can can MD cord-022526-j9kg00qf 3019 22 play play VB cord-022526-j9kg00qf 3019 23 a a DT cord-022526-j9kg00qf 3019 24 role role NN cord-022526-j9kg00qf 3019 25 in in IN cord-022526-j9kg00qf 3019 26 the the DT cord-022526-j9kg00qf 3019 27 therapeutic therapeutic JJ cord-022526-j9kg00qf 3019 28 management management NN cord-022526-j9kg00qf 3019 29 of of IN cord-022526-j9kg00qf 3019 30 EGUS EGUS NNP cord-022526-j9kg00qf 3019 31 ( ( -LRB- cord-022526-j9kg00qf 3019 32 Table Table NNP cord-022526-j9kg00qf 3019 33 13 13 CD cord-022526-j9kg00qf 3019 34 .10 .10 CD cord-022526-j9kg00qf 3019 35 - - SYM cord-022526-j9kg00qf 3019 36 2 2 CD cord-022526-j9kg00qf 3019 37 ) ) -RRB- cord-022526-j9kg00qf 3019 38 . . . cord-022526-j9kg00qf 3020 1 If if IN cord-022526-j9kg00qf 3020 2 gastroendoscopy gastroendoscopy NNP cord-022526-j9kg00qf 3020 3 is be VBZ cord-022526-j9kg00qf 3020 4 unavailable unavailable JJ cord-022526-j9kg00qf 3020 5 , , , cord-022526-j9kg00qf 3020 6 some some DT cord-022526-j9kg00qf 3020 7 guidelines guideline NNS cord-022526-j9kg00qf 3020 8 to to IN cord-022526-j9kg00qf 3020 9 therapy therapy NN cord-022526-j9kg00qf 3020 10 can can MD cord-022526-j9kg00qf 3020 11 be be VB cord-022526-j9kg00qf 3020 12 used use VBN cord-022526-j9kg00qf 3020 13 , , , cord-022526-j9kg00qf 3020 14 but but CC cord-022526-j9kg00qf 3020 15 the the DT cord-022526-j9kg00qf 3020 16 efficacy efficacy NN cord-022526-j9kg00qf 3020 17 of of IN cord-022526-j9kg00qf 3020 18 the the DT cord-022526-j9kg00qf 3020 19 treatment treatment NN cord-022526-j9kg00qf 3020 20 is be VBZ cord-022526-j9kg00qf 3020 21 based base VBN cord-022526-j9kg00qf 3020 22 on on IN cord-022526-j9kg00qf 3020 23 clinical clinical JJ cord-022526-j9kg00qf 3020 24 signs sign NNS cord-022526-j9kg00qf 3020 25 , , , cord-022526-j9kg00qf 3020 26 which which WDT cord-022526-j9kg00qf 3020 27 are be VBP cord-022526-j9kg00qf 3020 28 often often RB cord-022526-j9kg00qf 3020 29 vague vague JJ cord-022526-j9kg00qf 3020 30 or or CC cord-022526-j9kg00qf 3020 31 nonspecific nonspecific JJ cord-022526-j9kg00qf 3020 32 . . . cord-022526-j9kg00qf 3021 1 Signs sign NNS cord-022526-j9kg00qf 3021 2 of of IN cord-022526-j9kg00qf 3021 3 colic colic NN cord-022526-j9kg00qf 3021 4 or or CC cord-022526-j9kg00qf 3021 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3021 6 that that WDT cord-022526-j9kg00qf 3021 7 result result VBP cord-022526-j9kg00qf 3021 8 from from IN cord-022526-j9kg00qf 3021 9 gastric gastric JJ cord-022526-j9kg00qf 3021 10 ulcers ulcer NNS cord-022526-j9kg00qf 3021 11 often often RB cord-022526-j9kg00qf 3021 12 resolve resolve VBP cord-022526-j9kg00qf 3021 13 within within IN cord-022526-j9kg00qf 3021 14 48 48 CD cord-022526-j9kg00qf 3021 15 hours hour NNS cord-022526-j9kg00qf 3021 16 . . . cord-022526-j9kg00qf 3022 1 One one PRP cord-022526-j9kg00qf 3022 2 can can MD cord-022526-j9kg00qf 3022 3 note note VB cord-022526-j9kg00qf 3022 4 improvements improvement NNS cord-022526-j9kg00qf 3022 5 in in IN cord-022526-j9kg00qf 3022 6 appetite appetite NN cord-022526-j9kg00qf 3022 7 , , , cord-022526-j9kg00qf 3022 8 bodily bodily JJ cord-022526-j9kg00qf 3022 9 condition condition NN cord-022526-j9kg00qf 3022 10 , , , cord-022526-j9kg00qf 3022 11 and and CC cord-022526-j9kg00qf 3022 12 attitude attitude NN cord-022526-j9kg00qf 3022 13 within within IN cord-022526-j9kg00qf 3022 14 1 1 CD cord-022526-j9kg00qf 3022 15 to to IN cord-022526-j9kg00qf 3022 16 3 3 CD cord-022526-j9kg00qf 3022 17 weeks week NNS cord-022526-j9kg00qf 3022 18 . . . cord-022526-j9kg00qf 3023 1 If if IN cord-022526-j9kg00qf 3023 2 one one PRP cord-022526-j9kg00qf 3023 3 does do VBZ cord-022526-j9kg00qf 3023 4 not not RB cord-022526-j9kg00qf 3023 5 observe observe VB cord-022526-j9kg00qf 3023 6 improvement improvement NN cord-022526-j9kg00qf 3023 7 in in IN cord-022526-j9kg00qf 3023 8 clinical clinical JJ cord-022526-j9kg00qf 3023 9 signs sign NNS cord-022526-j9kg00qf 3023 10 , , , cord-022526-j9kg00qf 3023 11 treatment treatment NN cord-022526-j9kg00qf 3023 12 has have VBZ cord-022526-j9kg00qf 3023 13 not not RB cord-022526-j9kg00qf 3023 14 been be VBN cord-022526-j9kg00qf 3023 15 effective effective JJ cord-022526-j9kg00qf 3023 16 or or CC cord-022526-j9kg00qf 3023 17 gastric gastric JJ cord-022526-j9kg00qf 3023 18 ulceration ulceration NN cord-022526-j9kg00qf 3023 19 was be VBD cord-022526-j9kg00qf 3023 20 not not RB cord-022526-j9kg00qf 3023 21 the the DT cord-022526-j9kg00qf 3023 22 primary primary JJ cord-022526-j9kg00qf 3023 23 problem problem NN cord-022526-j9kg00qf 3023 24 . . . cord-022526-j9kg00qf 3024 1 The the DT cord-022526-j9kg00qf 3024 2 principal principal JJ cord-022526-j9kg00qf 3024 3 therapeutic therapeutic JJ cord-022526-j9kg00qf 3024 4 options option NNS cord-022526-j9kg00qf 3024 5 for for IN cord-022526-j9kg00qf 3024 6 ulcer ulcer NN cord-022526-j9kg00qf 3024 7 treatment treatment NN cord-022526-j9kg00qf 3024 8 include include VBP cord-022526-j9kg00qf 3024 9 H h NN cord-022526-j9kg00qf 3024 10 2 2 CD cord-022526-j9kg00qf 3024 11 antagonists antagonist NNS cord-022526-j9kg00qf 3024 12 ( ( -LRB- cord-022526-j9kg00qf 3024 13 cimetidine cimetidine NN cord-022526-j9kg00qf 3024 14 , , , cord-022526-j9kg00qf 3024 15 ranitidine ranitidine NN cord-022526-j9kg00qf 3024 16 , , , cord-022526-j9kg00qf 3024 17 famotidine famotidine NN cord-022526-j9kg00qf 3024 18 , , , cord-022526-j9kg00qf 3024 19 nizatidine nizatidine NNP cord-022526-j9kg00qf 3024 20 ) ) -RRB- cord-022526-j9kg00qf 3024 21 , , , cord-022526-j9kg00qf 3024 22 proton proton NN cord-022526-j9kg00qf 3024 23 pump pump NN cord-022526-j9kg00qf 3024 24 blockers blocker NNS cord-022526-j9kg00qf 3024 25 ( ( -LRB- cord-022526-j9kg00qf 3024 26 omeprazole omeprazole NN cord-022526-j9kg00qf 3024 27 , , , cord-022526-j9kg00qf 3024 28 pantoprazole pantoprazole NNP cord-022526-j9kg00qf 3024 29 , , , cord-022526-j9kg00qf 3024 30 rabeprazole rabeprazole NNP cord-022526-j9kg00qf 3024 31 , , , cord-022526-j9kg00qf 3024 32 esomeprazole esomeprazole NN cord-022526-j9kg00qf 3024 33 ) ) -RRB- cord-022526-j9kg00qf 3024 34 , , , cord-022526-j9kg00qf 3024 35 the the DT cord-022526-j9kg00qf 3024 36 mucosal mucosal JJ cord-022526-j9kg00qf 3024 37 adherent adherent NN cord-022526-j9kg00qf 3024 38 sucralfate sucralfate JJ cord-022526-j9kg00qf 3024 39 , , , cord-022526-j9kg00qf 3024 40 and and CC cord-022526-j9kg00qf 3024 41 antacids antacid NNS cord-022526-j9kg00qf 3024 42 . . . cord-022526-j9kg00qf 3025 1 The the DT cord-022526-j9kg00qf 3025 2 H h NN cord-022526-j9kg00qf 3025 3 2 2 CD cord-022526-j9kg00qf 3025 4 antagonists antagonist NNS cord-022526-j9kg00qf 3025 5 suppress suppress VBP cord-022526-j9kg00qf 3025 6 hydrochloric hydrochloric JJ cord-022526-j9kg00qf 3025 7 acid acid NN cord-022526-j9kg00qf 3025 8 secretion secretion NN cord-022526-j9kg00qf 3025 9 through through IN cord-022526-j9kg00qf 3025 10 competitive competitive JJ cord-022526-j9kg00qf 3025 11 inhibition inhibition NN cord-022526-j9kg00qf 3025 12 of of IN cord-022526-j9kg00qf 3025 13 the the DT cord-022526-j9kg00qf 3025 14 parietal parietal JJ cord-022526-j9kg00qf 3025 15 cell cell NN cord-022526-j9kg00qf 3025 16 histamine histamine NN cord-022526-j9kg00qf 3025 17 receptor receptor NN cord-022526-j9kg00qf 3025 18 that that WDT cord-022526-j9kg00qf 3025 19 can can MD cord-022526-j9kg00qf 3025 20 be be VB cord-022526-j9kg00qf 3025 21 overcome overcome VBN cord-022526-j9kg00qf 3025 22 partially partially RB cord-022526-j9kg00qf 3025 23 with with IN cord-022526-j9kg00qf 3025 24 exogenous exogenous JJ cord-022526-j9kg00qf 3025 25 pentagastrin pentagastrin NN cord-022526-j9kg00qf 3025 26 . . . cord-022526-j9kg00qf 3026 1 61 61 CD cord-022526-j9kg00qf 3026 2 Use Use NNP cord-022526-j9kg00qf 3026 3 of of IN cord-022526-j9kg00qf 3026 4 H H NNP cord-022526-j9kg00qf 3026 5 2 2 CD cord-022526-j9kg00qf 3026 6 antagonists antagonist NNS cord-022526-j9kg00qf 3026 7 has have VBZ cord-022526-j9kg00qf 3026 8 been be VBN cord-022526-j9kg00qf 3026 9 successful successful JJ cord-022526-j9kg00qf 3026 10 in in IN cord-022526-j9kg00qf 3026 11 raising raise VBG cord-022526-j9kg00qf 3026 12 gastric gastric JJ cord-022526-j9kg00qf 3026 13 pH ph NN cord-022526-j9kg00qf 3026 14 and and CC cord-022526-j9kg00qf 3026 15 resolving resolve VBG cord-022526-j9kg00qf 3026 16 gastric gastric JJ cord-022526-j9kg00qf 3026 17 lesions lesion NNS cord-022526-j9kg00qf 3026 18 in in IN cord-022526-j9kg00qf 3026 19 foals foal NNS cord-022526-j9kg00qf 3026 20 and and CC cord-022526-j9kg00qf 3026 21 adult adult NN cord-022526-j9kg00qf 3026 22 horses horse NNS cord-022526-j9kg00qf 3026 23 . . . cord-022526-j9kg00qf 3027 1 29 29 CD cord-022526-j9kg00qf 3027 2 , , , cord-022526-j9kg00qf 3027 3 55 55 CD cord-022526-j9kg00qf 3027 4 , , , cord-022526-j9kg00qf 3027 5 62 62 CD cord-022526-j9kg00qf 3027 6 Clinical clinical JJ cord-022526-j9kg00qf 3027 7 and and CC cord-022526-j9kg00qf 3027 8 experimental experimental JJ cord-022526-j9kg00qf 3027 9 evidence evidence NN cord-022526-j9kg00qf 3027 10 has have VBZ cord-022526-j9kg00qf 3027 11 demonstrated demonstrate VBN cord-022526-j9kg00qf 3027 12 greater great JJR cord-022526-j9kg00qf 3027 13 individual individual JJ cord-022526-j9kg00qf 3027 14 variability variability NN cord-022526-j9kg00qf 3027 15 with with IN cord-022526-j9kg00qf 3027 16 lower low JJR cord-022526-j9kg00qf 3027 17 dosages dosage NNS cord-022526-j9kg00qf 3027 18 of of IN cord-022526-j9kg00qf 3027 19 H H NNP cord-022526-j9kg00qf 3027 20 2 2 CD cord-022526-j9kg00qf 3027 21 antagonists antagonist NNS cord-022526-j9kg00qf 3027 22 . . . cord-022526-j9kg00qf 3028 1 63 63 CD cord-022526-j9kg00qf 3029 1 Thus thus RB cord-022526-j9kg00qf 3029 2 dosage dosage NN cord-022526-j9kg00qf 3029 3 recommendations recommendation NNS cord-022526-j9kg00qf 3029 4 are be VBP cord-022526-j9kg00qf 3029 5 based base VBN cord-022526-j9kg00qf 3029 6 on on IN cord-022526-j9kg00qf 3029 7 levels level NNS cord-022526-j9kg00qf 3029 8 necessary necessary JJ cord-022526-j9kg00qf 3029 9 to to TO cord-022526-j9kg00qf 3029 10 increase increase VB cord-022526-j9kg00qf 3029 11 gastric gastric JJ cord-022526-j9kg00qf 3029 12 pH ph NN cord-022526-j9kg00qf 3029 13 and and CC cord-022526-j9kg00qf 3029 14 promote promote VB cord-022526-j9kg00qf 3029 15 ulcer ulcer NN cord-022526-j9kg00qf 3029 16 healing healing NN cord-022526-j9kg00qf 3029 17 in in IN cord-022526-j9kg00qf 3029 18 a a DT cord-022526-j9kg00qf 3029 19 majority majority NN cord-022526-j9kg00qf 3029 20 of of IN cord-022526-j9kg00qf 3029 21 horses horse NNS cord-022526-j9kg00qf 3029 22 . . . cord-022526-j9kg00qf 3030 1 Commonly commonly RB cord-022526-j9kg00qf 3030 2 recommended recommend VBN cord-022526-j9kg00qf 3030 3 dosages dosage NNS cord-022526-j9kg00qf 3030 4 are be VBP cord-022526-j9kg00qf 3030 5 20 20 CD cord-022526-j9kg00qf 3030 6 to to TO cord-022526-j9kg00qf 3030 7 30 30 CD cord-022526-j9kg00qf 3030 8 mg mg NN cord-022526-j9kg00qf 3030 9 / / SYM cord-022526-j9kg00qf 3030 10 kg kg CC cord-022526-j9kg00qf 3030 11 orally orally RB cord-022526-j9kg00qf 3030 12 every every DT cord-022526-j9kg00qf 3030 13 8 8 CD cord-022526-j9kg00qf 3030 14 hours hour NNS cord-022526-j9kg00qf 3030 15 or or CC cord-022526-j9kg00qf 3030 16 6.6 6.6 CD cord-022526-j9kg00qf 3030 17 mg mg NNP cord-022526-j9kg00qf 3030 18 / / SYM cord-022526-j9kg00qf 3030 19 kg kg CC cord-022526-j9kg00qf 3030 20 intravenously intravenously RB cord-022526-j9kg00qf 3030 21 every every DT cord-022526-j9kg00qf 3030 22 6 6 CD cord-022526-j9kg00qf 3030 23 hours hour NNS cord-022526-j9kg00qf 3030 24 for for IN cord-022526-j9kg00qf 3030 25 cimetidine cimetidine NN cord-022526-j9kg00qf 3030 26 and and CC cord-022526-j9kg00qf 3030 27 6.6 6.6 CD cord-022526-j9kg00qf 3030 28 mg mg NNP cord-022526-j9kg00qf 3030 29 / / SYM cord-022526-j9kg00qf 3030 30 kg kg VBZ cord-022526-j9kg00qf 3030 31 orally orally RB cord-022526-j9kg00qf 3030 32 every every DT cord-022526-j9kg00qf 3030 33 8 8 CD cord-022526-j9kg00qf 3030 34 hours hour NNS cord-022526-j9kg00qf 3030 35 or or CC cord-022526-j9kg00qf 3031 1 1.5 1.5 CD cord-022526-j9kg00qf 3031 2 to to IN cord-022526-j9kg00qf 3031 3 2 2 CD cord-022526-j9kg00qf 3031 4 mg mg NNP cord-022526-j9kg00qf 3031 5 / / SYM cord-022526-j9kg00qf 3031 6 kg kg CC cord-022526-j9kg00qf 3031 7 intravenously intravenously RB cord-022526-j9kg00qf 3031 8 every every DT cord-022526-j9kg00qf 3031 9 6 6 CD cord-022526-j9kg00qf 3031 10 hours hour NNS cord-022526-j9kg00qf 3031 11 for for IN cord-022526-j9kg00qf 3031 12 ranitidine ranitidine NN cord-022526-j9kg00qf 3031 13 . . . cord-022526-j9kg00qf 3032 1 Famotidine Famotidine NNP cord-022526-j9kg00qf 3032 2 has have VBZ cord-022526-j9kg00qf 3032 3 been be VBN cord-022526-j9kg00qf 3032 4 used use VBN cord-022526-j9kg00qf 3032 5 less less RBR cord-022526-j9kg00qf 3032 6 extensively extensively RB cord-022526-j9kg00qf 3032 7 in in IN cord-022526-j9kg00qf 3032 8 the the DT cord-022526-j9kg00qf 3032 9 horse horse NN cord-022526-j9kg00qf 3032 10 , , , cord-022526-j9kg00qf 3032 11 but but CC cord-022526-j9kg00qf 3032 12 a a DT cord-022526-j9kg00qf 3032 13 dose dose NN cord-022526-j9kg00qf 3032 14 of of IN cord-022526-j9kg00qf 3032 15 10 10 CD cord-022526-j9kg00qf 3032 16 to to TO cord-022526-j9kg00qf 3032 17 15 15 CD cord-022526-j9kg00qf 3032 18 mg mg NNP cord-022526-j9kg00qf 3032 19 / / SYM cord-022526-j9kg00qf 3032 20 kg kg NNP cord-022526-j9kg00qf 3032 21 / / SYM cord-022526-j9kg00qf 3032 22 day day NN cord-022526-j9kg00qf 3032 23 has have VBZ cord-022526-j9kg00qf 3032 24 been be VBN cord-022526-j9kg00qf 3032 25 recommended recommend VBN cord-022526-j9kg00qf 3032 26 . . . cord-022526-j9kg00qf 3033 1 Because because IN cord-022526-j9kg00qf 3033 2 gastric gastric JJ cord-022526-j9kg00qf 3033 3 perforation perforation NN cord-022526-j9kg00qf 3033 4 caused cause VBN cord-022526-j9kg00qf 3033 5 by by IN cord-022526-j9kg00qf 3033 6 glandular glandular JJ cord-022526-j9kg00qf 3033 7 ulcer ulcer NN cord-022526-j9kg00qf 3033 8 disease disease NN cord-022526-j9kg00qf 3033 9 has have VBZ cord-022526-j9kg00qf 3033 10 been be VBN cord-022526-j9kg00qf 3033 11 reported report VBN cord-022526-j9kg00qf 3033 12 in in IN cord-022526-j9kg00qf 3033 13 hospitalized hospitalize VBN cord-022526-j9kg00qf 3033 14 neonates neonate NNS cord-022526-j9kg00qf 3033 15 , , , cord-022526-j9kg00qf 3033 16 many many JJ cord-022526-j9kg00qf 3033 17 clinicians clinician NNS cord-022526-j9kg00qf 3033 18 routinely routinely RB cord-022526-j9kg00qf 3033 19 use use VBP cord-022526-j9kg00qf 3033 20 prophylactic prophylactic JJ cord-022526-j9kg00qf 3033 21 antiulcer antiulcer NN cord-022526-j9kg00qf 3033 22 therapy therapy NN cord-022526-j9kg00qf 3033 23 in in IN cord-022526-j9kg00qf 3033 24 this this DT cord-022526-j9kg00qf 3033 25 population population NN cord-022526-j9kg00qf 3033 26 . . . cord-022526-j9kg00qf 3034 1 Although although IN cord-022526-j9kg00qf 3034 2 clinically clinically RB cord-022526-j9kg00qf 3034 3 normal normal JJ cord-022526-j9kg00qf 3034 4 foals foal NNS cord-022526-j9kg00qf 3034 5 respond respond VBP cord-022526-j9kg00qf 3034 6 predictably predictably RB cord-022526-j9kg00qf 3034 7 to to IN cord-022526-j9kg00qf 3034 8 ranitidine ranitidine NN cord-022526-j9kg00qf 3034 9 , , , cord-022526-j9kg00qf 3034 10 29 29 CD cord-022526-j9kg00qf 3034 11 sick sick JJ cord-022526-j9kg00qf 3034 12 neonates neonate NNS cord-022526-j9kg00qf 3034 13 have have VBP cord-022526-j9kg00qf 3034 14 shown show VBN cord-022526-j9kg00qf 3034 15 variability variability NN cord-022526-j9kg00qf 3034 16 in in IN cord-022526-j9kg00qf 3034 17 pH pH NNP cord-022526-j9kg00qf 3034 18 response response NN cord-022526-j9kg00qf 3034 19 to to IN cord-022526-j9kg00qf 3034 20 intravenously intravenously RB cord-022526-j9kg00qf 3034 21 administered administer VBN cord-022526-j9kg00qf 3034 22 ranitidine ranitidine NN cord-022526-j9kg00qf 3034 23 , , , cord-022526-j9kg00qf 3034 24 with with IN cord-022526-j9kg00qf 3034 25 a a DT cord-022526-j9kg00qf 3034 26 much much RB cord-022526-j9kg00qf 3034 27 shorter short JJR cord-022526-j9kg00qf 3034 28 duration duration NN cord-022526-j9kg00qf 3034 29 of of IN cord-022526-j9kg00qf 3034 30 action action NN cord-022526-j9kg00qf 3034 31 and and CC cord-022526-j9kg00qf 3034 32 in in IN cord-022526-j9kg00qf 3034 33 some some DT cord-022526-j9kg00qf 3034 34 cases case NNS cord-022526-j9kg00qf 3034 35 no no DT cord-022526-j9kg00qf 3034 36 noticeable noticeable JJ cord-022526-j9kg00qf 3034 37 response response NN cord-022526-j9kg00qf 3034 38 . . . cord-022526-j9kg00qf 3035 1 31 31 CD cord-022526-j9kg00qf 3036 1 Thus thus RB cord-022526-j9kg00qf 3036 2 currently currently RB cord-022526-j9kg00qf 3036 3 used use VBN cord-022526-j9kg00qf 3036 4 dosing dosing NN cord-022526-j9kg00qf 3036 5 schedules schedule NNS cord-022526-j9kg00qf 3036 6 for for IN cord-022526-j9kg00qf 3036 7 hospitalized hospitalize VBN cord-022526-j9kg00qf 3036 8 foals foal NNS cord-022526-j9kg00qf 3036 9 may may MD cord-022526-j9kg00qf 3036 10 be be VB cord-022526-j9kg00qf 3036 11 inadequate inadequate JJ cord-022526-j9kg00qf 3036 12 . . . cord-022526-j9kg00qf 3037 1 Because because IN cord-022526-j9kg00qf 3037 2 some some DT cord-022526-j9kg00qf 3037 3 critically critically RB cord-022526-j9kg00qf 3037 4 ill ill JJ cord-022526-j9kg00qf 3037 5 foals foal NNS cord-022526-j9kg00qf 3037 6 have have VBP cord-022526-j9kg00qf 3037 7 a a DT cord-022526-j9kg00qf 3037 8 predominantly predominantly RB cord-022526-j9kg00qf 3037 9 alkaline alkaline JJ cord-022526-j9kg00qf 3037 10 gastric gastric JJ cord-022526-j9kg00qf 3037 11 pH ph NN cord-022526-j9kg00qf 3037 12 profile profile NN cord-022526-j9kg00qf 3037 13 and and CC cord-022526-j9kg00qf 3037 14 because because IN cord-022526-j9kg00qf 3037 15 gastric gastric JJ cord-022526-j9kg00qf 3037 16 acidity acidity NN cord-022526-j9kg00qf 3037 17 may may MD cord-022526-j9kg00qf 3037 18 be be VB cord-022526-j9kg00qf 3037 19 protective protective JJ cord-022526-j9kg00qf 3037 20 against against IN cord-022526-j9kg00qf 3037 21 bacterial bacterial JJ cord-022526-j9kg00qf 3037 22 translocation translocation NN cord-022526-j9kg00qf 3037 23 in in IN cord-022526-j9kg00qf 3037 24 neonates neonate NNS cord-022526-j9kg00qf 3037 25 , , , cord-022526-j9kg00qf 3037 26 the the DT cord-022526-j9kg00qf 3037 27 need need NN cord-022526-j9kg00qf 3037 28 for for IN cord-022526-j9kg00qf 3037 29 prophylactic prophylactic JJ cord-022526-j9kg00qf 3037 30 ulcer ulcer NN cord-022526-j9kg00qf 3037 31 therapy therapy NN cord-022526-j9kg00qf 3037 32 is be VBZ cord-022526-j9kg00qf 3037 33 controversial controversial JJ cord-022526-j9kg00qf 3037 34 . . . cord-022526-j9kg00qf 3038 1 In in IN cord-022526-j9kg00qf 3038 2 critically critically RB cord-022526-j9kg00qf 3038 3 ill ill JJ cord-022526-j9kg00qf 3038 4 human human JJ cord-022526-j9kg00qf 3038 5 neonates neonate NNS cord-022526-j9kg00qf 3038 6 , , , cord-022526-j9kg00qf 3038 7 intravenous intravenous JJ cord-022526-j9kg00qf 3038 8 administration administration NN cord-022526-j9kg00qf 3038 9 of of IN cord-022526-j9kg00qf 3038 10 ranitidine ranitidine NNP cord-022526-j9kg00qf 3038 11 raises raise VBZ cord-022526-j9kg00qf 3038 12 gastric gastric JJ cord-022526-j9kg00qf 3038 13 pH ph NN cord-022526-j9kg00qf 3038 14 and and CC cord-022526-j9kg00qf 3038 15 gastric gastric JJ cord-022526-j9kg00qf 3038 16 bacterial bacterial JJ cord-022526-j9kg00qf 3038 17 colonization colonization NN cord-022526-j9kg00qf 3038 18 but but CC cord-022526-j9kg00qf 3038 19 does do VBZ cord-022526-j9kg00qf 3038 20 not not RB cord-022526-j9kg00qf 3038 21 increase increase VB cord-022526-j9kg00qf 3038 22 the the DT cord-022526-j9kg00qf 3038 23 risk risk NN cord-022526-j9kg00qf 3038 24 of of IN cord-022526-j9kg00qf 3038 25 sepsis sepsis NN cord-022526-j9kg00qf 3038 26 . . . cord-022526-j9kg00qf 3039 1 64 64 CD cord-022526-j9kg00qf 3040 1 In in IN cord-022526-j9kg00qf 3040 2 a a DT cord-022526-j9kg00qf 3040 3 retrospective retrospective JJ cord-022526-j9kg00qf 3040 4 study study NN cord-022526-j9kg00qf 3040 5 of of IN cord-022526-j9kg00qf 3040 6 85 85 CD cord-022526-j9kg00qf 3040 7 hospitalized hospitalize VBN cord-022526-j9kg00qf 3040 8 foals foal NNS cord-022526-j9kg00qf 3040 9 less less JJR cord-022526-j9kg00qf 3040 10 than than IN cord-022526-j9kg00qf 3040 11 30 30 CD cord-022526-j9kg00qf 3040 12 days day NNS cord-022526-j9kg00qf 3040 13 of of IN cord-022526-j9kg00qf 3040 14 age age NN cord-022526-j9kg00qf 3040 15 , , , cord-022526-j9kg00qf 3040 16 no no DT cord-022526-j9kg00qf 3040 17 difference difference NN cord-022526-j9kg00qf 3040 18 in in IN cord-022526-j9kg00qf 3040 19 the the DT cord-022526-j9kg00qf 3040 20 frequency frequency NN cord-022526-j9kg00qf 3040 21 of of IN cord-022526-j9kg00qf 3040 22 gastric gastric JJ cord-022526-j9kg00qf 3040 23 ulceration ulceration NN cord-022526-j9kg00qf 3040 24 at at IN cord-022526-j9kg00qf 3040 25 necropsy necropsy JJ cord-022526-j9kg00qf 3040 26 was be VBD cord-022526-j9kg00qf 3040 27 found find VBN cord-022526-j9kg00qf 3040 28 between between IN cord-022526-j9kg00qf 3040 29 those those DT cord-022526-j9kg00qf 3040 30 foals foal NNS cord-022526-j9kg00qf 3040 31 that that WDT cord-022526-j9kg00qf 3040 32 received receive VBD cord-022526-j9kg00qf 3040 33 prophylactic prophylactic JJ cord-022526-j9kg00qf 3040 34 treatment treatment NN cord-022526-j9kg00qf 3040 35 for for IN cord-022526-j9kg00qf 3040 36 gastric gastric JJ cord-022526-j9kg00qf 3040 37 ulcers ulcer NNS cord-022526-j9kg00qf 3040 38 and and CC cord-022526-j9kg00qf 3040 39 those those DT cord-022526-j9kg00qf 3040 40 that that WDT cord-022526-j9kg00qf 3040 41 did do VBD cord-022526-j9kg00qf 3040 42 not not RB cord-022526-j9kg00qf 3040 43 . . . cord-022526-j9kg00qf 3041 1 65 65 CD cord-022526-j9kg00qf 3042 1 Because because IN cord-022526-j9kg00qf 3042 2 the the DT cord-022526-j9kg00qf 3042 3 study study NN cord-022526-j9kg00qf 3042 4 was be VBD cord-022526-j9kg00qf 3042 5 retrospective retrospective JJ cord-022526-j9kg00qf 3042 6 , , , cord-022526-j9kg00qf 3042 7 specific specific JJ cord-022526-j9kg00qf 3042 8 details detail NNS cord-022526-j9kg00qf 3042 9 regarding regard VBG cord-022526-j9kg00qf 3042 10 lesion lesion NN cord-022526-j9kg00qf 3042 11 location location NN cord-022526-j9kg00qf 3042 12 and and CC cord-022526-j9kg00qf 3042 13 severity severity NN cord-022526-j9kg00qf 3042 14 were be VBD cord-022526-j9kg00qf 3042 15 not not RB cord-022526-j9kg00qf 3042 16 available available JJ cord-022526-j9kg00qf 3042 17 ; ; : cord-022526-j9kg00qf 3042 18 however however RB cord-022526-j9kg00qf 3042 19 , , , cord-022526-j9kg00qf 3042 20 none none NN cord-022526-j9kg00qf 3042 21 of of IN cord-022526-j9kg00qf 3042 22 the the DT cord-022526-j9kg00qf 3042 23 foals foal NNS cord-022526-j9kg00qf 3042 24 in in IN cord-022526-j9kg00qf 3042 25 the the DT cord-022526-j9kg00qf 3042 26 study study NN cord-022526-j9kg00qf 3042 27 died die VBD cord-022526-j9kg00qf 3042 28 because because IN cord-022526-j9kg00qf 3042 29 of of IN cord-022526-j9kg00qf 3042 30 gastric gastric JJ cord-022526-j9kg00qf 3042 31 ulcer ulcer NN cord-022526-j9kg00qf 3042 32 disease disease NN cord-022526-j9kg00qf 3042 33 . . . cord-022526-j9kg00qf 3043 1 H h NN cord-022526-j9kg00qf 3043 2 2 2 CD cord-022526-j9kg00qf 3043 3 antagonist antagonist NN cord-022526-j9kg00qf 3043 4 therapy therapy NN cord-022526-j9kg00qf 3043 5 should should MD cord-022526-j9kg00qf 3043 6 continue continue VB cord-022526-j9kg00qf 3043 7 for for IN cord-022526-j9kg00qf 3043 8 14 14 CD cord-022526-j9kg00qf 3043 9 to to TO cord-022526-j9kg00qf 3043 10 21 21 CD cord-022526-j9kg00qf 3043 11 days day NNS cord-022526-j9kg00qf 3043 12 , , , cord-022526-j9kg00qf 3043 13 but but CC cord-022526-j9kg00qf 3043 14 complete complete JJ cord-022526-j9kg00qf 3043 15 ulcer ulcer NN cord-022526-j9kg00qf 3043 16 healing healing NN cord-022526-j9kg00qf 3043 17 may may MD cord-022526-j9kg00qf 3043 18 take take VB cord-022526-j9kg00qf 3043 19 30 30 CD cord-022526-j9kg00qf 3043 20 to to TO cord-022526-j9kg00qf 3043 21 40 40 CD cord-022526-j9kg00qf 3043 22 days day NNS cord-022526-j9kg00qf 3043 23 . . . cord-022526-j9kg00qf 3044 1 If if IN cord-022526-j9kg00qf 3044 2 an an DT cord-022526-j9kg00qf 3044 3 animal animal NN cord-022526-j9kg00qf 3044 4 is be VBZ cord-022526-j9kg00qf 3044 5 kept keep VBN cord-022526-j9kg00qf 3044 6 in in IN cord-022526-j9kg00qf 3044 7 race race NN cord-022526-j9kg00qf 3044 8 training training NN cord-022526-j9kg00qf 3044 9 during during IN cord-022526-j9kg00qf 3044 10 therapy therapy NN cord-022526-j9kg00qf 3044 11 , , , cord-022526-j9kg00qf 3044 12 clinical clinical JJ cord-022526-j9kg00qf 3044 13 signs sign NNS cord-022526-j9kg00qf 3044 14 may may MD cord-022526-j9kg00qf 3044 15 resolve resolve VB cord-022526-j9kg00qf 3044 16 but but CC cord-022526-j9kg00qf 3044 17 the the DT cord-022526-j9kg00qf 3044 18 lesions lesion NNS cord-022526-j9kg00qf 3044 19 may may MD cord-022526-j9kg00qf 3044 20 not not RB cord-022526-j9kg00qf 3044 21 . . . cord-022526-j9kg00qf 3045 1 Currently currently RB cord-022526-j9kg00qf 3045 2 , , , cord-022526-j9kg00qf 3045 3 cimetidine cimetidine NN cord-022526-j9kg00qf 3045 4 and and CC cord-022526-j9kg00qf 3045 5 ranitidine ranitidine NN cord-022526-j9kg00qf 3045 6 are be VBP cord-022526-j9kg00qf 3045 7 available available JJ cord-022526-j9kg00qf 3045 8 in in IN cord-022526-j9kg00qf 3045 9 injectable injectable JJ cord-022526-j9kg00qf 3045 10 , , , cord-022526-j9kg00qf 3045 11 tablet tablet NN cord-022526-j9kg00qf 3045 12 , , , cord-022526-j9kg00qf 3045 13 and and CC cord-022526-j9kg00qf 3045 14 liquid liquid JJ cord-022526-j9kg00qf 3045 15 forms form NNS cord-022526-j9kg00qf 3045 16 . . . cord-022526-j9kg00qf 3046 1 Famotidine Famotidine NNP cord-022526-j9kg00qf 3046 2 and and CC cord-022526-j9kg00qf 3046 3 nizatidine nizatidine NN cord-022526-j9kg00qf 3046 4 are be VBP cord-022526-j9kg00qf 3046 5 available available JJ cord-022526-j9kg00qf 3046 6 in in IN cord-022526-j9kg00qf 3046 7 tablets tablet NNS cord-022526-j9kg00qf 3046 8 . . . cord-022526-j9kg00qf 3047 1 Proton proton NN cord-022526-j9kg00qf 3047 2 pump pump NN cord-022526-j9kg00qf 3047 3 inhibitors inhibitor NNS cord-022526-j9kg00qf 3047 4 block block VBP cord-022526-j9kg00qf 3047 5 secretion secretion NN cord-022526-j9kg00qf 3047 6 of of IN cord-022526-j9kg00qf 3047 7 H h NN cord-022526-j9kg00qf 3047 8 + + CC cord-022526-j9kg00qf 3047 9 at at IN cord-022526-j9kg00qf 3047 10 the the DT cord-022526-j9kg00qf 3047 11 parietal parietal JJ cord-022526-j9kg00qf 3047 12 cell cell NN cord-022526-j9kg00qf 3047 13 membrane membrane NN cord-022526-j9kg00qf 3047 14 by by IN cord-022526-j9kg00qf 3047 15 irreversibly irreversibly RB cord-022526-j9kg00qf 3047 16 binding bind VBG cord-022526-j9kg00qf 3047 17 to to IN cord-022526-j9kg00qf 3047 18 the the DT cord-022526-j9kg00qf 3047 19 H h NN cord-022526-j9kg00qf 3047 20 + + FW cord-022526-j9kg00qf 3047 21 , , . cord-022526-j9kg00qf 3048 1 K K NNP cord-022526-j9kg00qf 3048 2 + + CC cord-022526-j9kg00qf 3049 1 -ATPase -ATPase NNP cord-022526-j9kg00qf 3050 1 proton proton NN cord-022526-j9kg00qf 3050 2 pump pump NN cord-022526-j9kg00qf 3050 3 of of IN cord-022526-j9kg00qf 3050 4 the the DT cord-022526-j9kg00qf 3050 5 cell cell NN cord-022526-j9kg00qf 3050 6 . . . cord-022526-j9kg00qf 3051 1 These these DT cord-022526-j9kg00qf 3051 2 agents agent NNS cord-022526-j9kg00qf 3051 3 have have VBP cord-022526-j9kg00qf 3051 4 a a DT cord-022526-j9kg00qf 3051 5 prolonged prolong VBN cord-022526-j9kg00qf 3051 6 antisecretory antisecretory NN cord-022526-j9kg00qf 3051 7 effect effect NN cord-022526-j9kg00qf 3051 8 , , , cord-022526-j9kg00qf 3051 9 which which WDT cord-022526-j9kg00qf 3051 10 allows allow VBZ cord-022526-j9kg00qf 3051 11 for for IN cord-022526-j9kg00qf 3051 12 once once RB cord-022526-j9kg00qf 3051 13 - - HYPH cord-022526-j9kg00qf 3051 14 daily daily NN cord-022526-j9kg00qf 3051 15 dosing dosing NN cord-022526-j9kg00qf 3051 16 . . . cord-022526-j9kg00qf 3052 1 Omeprazole Omeprazole NNP cord-022526-j9kg00qf 3052 2 , , , cord-022526-j9kg00qf 3052 3 the the DT cord-022526-j9kg00qf 3052 4 first first JJ cord-022526-j9kg00qf 3052 5 proton proton NN cord-022526-j9kg00qf 3052 6 pump pump NN cord-022526-j9kg00qf 3052 7 inhibitor inhibitor NN cord-022526-j9kg00qf 3052 8 to to TO cord-022526-j9kg00qf 3052 9 be be VB cord-022526-j9kg00qf 3052 10 developed develop VBN cord-022526-j9kg00qf 3052 11 , , , cord-022526-j9kg00qf 3052 12 is be VBZ cord-022526-j9kg00qf 3052 13 the the DT cord-022526-j9kg00qf 3052 14 only only RB cord-022526-j9kg00qf 3052 15 currently currently RB cord-022526-j9kg00qf 3052 16 approved approve VBN cord-022526-j9kg00qf 3052 17 agent agent NN cord-022526-j9kg00qf 3052 18 for for IN cord-022526-j9kg00qf 3052 19 the the DT cord-022526-j9kg00qf 3052 20 treatment treatment NN cord-022526-j9kg00qf 3052 21 of of IN cord-022526-j9kg00qf 3052 22 EGUS egu NNS cord-022526-j9kg00qf 3052 23 . . . cord-022526-j9kg00qf 3053 1 Several several JJ cord-022526-j9kg00qf 3053 2 studies study NNS cord-022526-j9kg00qf 3053 3 have have VBP cord-022526-j9kg00qf 3053 4 documented document VBN cord-022526-j9kg00qf 3053 5 the the DT cord-022526-j9kg00qf 3053 6 safety safety NN cord-022526-j9kg00qf 3053 7 of of IN cord-022526-j9kg00qf 3053 8 orally orally RB cord-022526-j9kg00qf 3053 9 administered administer VBN cord-022526-j9kg00qf 3053 10 omeprazole omeprazole NN cord-022526-j9kg00qf 3053 11 in in IN cord-022526-j9kg00qf 3053 12 foals foal NNS cord-022526-j9kg00qf 3053 13 and and CC cord-022526-j9kg00qf 3053 14 adult adult NN cord-022526-j9kg00qf 3053 15 horses horse NNS cord-022526-j9kg00qf 3053 16 . . . cord-022526-j9kg00qf 3054 1 66 66 CD cord-022526-j9kg00qf 3055 1 , , , cord-022526-j9kg00qf 3055 2 67 67 CD cord-022526-j9kg00qf 3055 3 Omeprazole Omeprazole NNP cord-022526-j9kg00qf 3055 4 has have VBZ cord-022526-j9kg00qf 3055 5 demonstrated demonstrate VBN cord-022526-j9kg00qf 3055 6 efficacy efficacy NN cord-022526-j9kg00qf 3055 7 in in IN cord-022526-j9kg00qf 3055 8 the the DT cord-022526-j9kg00qf 3055 9 healing healing NN cord-022526-j9kg00qf 3055 10 of of IN cord-022526-j9kg00qf 3055 11 NSAID NSAID NNP cord-022526-j9kg00qf 3055 12 - - HYPH cord-022526-j9kg00qf 3055 13 induced induce VBN cord-022526-j9kg00qf 3055 14 ulcers ulcer NNS cord-022526-j9kg00qf 3055 15 in in IN cord-022526-j9kg00qf 3055 16 horses horse NNS cord-022526-j9kg00qf 3055 17 and and CC cord-022526-j9kg00qf 3055 18 in in IN cord-022526-j9kg00qf 3055 19 naturally naturally RB cord-022526-j9kg00qf 3055 20 occurring occur VBG cord-022526-j9kg00qf 3055 21 cases case NNS cord-022526-j9kg00qf 3055 22 of of IN cord-022526-j9kg00qf 3055 23 EGUS egu NNS cord-022526-j9kg00qf 3055 24 . . . cord-022526-j9kg00qf 3056 1 68 68 CD cord-022526-j9kg00qf 3057 1 , , , cord-022526-j9kg00qf 3057 2 69 69 CD cord-022526-j9kg00qf 3057 3 More more RBR cord-022526-j9kg00qf 3057 4 importantly importantly RB cord-022526-j9kg00qf 3057 5 , , , cord-022526-j9kg00qf 3057 6 omeprazole omeprazole NN cord-022526-j9kg00qf 3057 7 has have VBZ cord-022526-j9kg00qf 3057 8 been be VBN cord-022526-j9kg00qf 3057 9 shown show VBN cord-022526-j9kg00qf 3057 10 to to TO cord-022526-j9kg00qf 3057 11 eliminate eliminate VB cord-022526-j9kg00qf 3057 12 or or CC cord-022526-j9kg00qf 3057 13 reduce reduce VB cord-022526-j9kg00qf 3057 14 the the DT cord-022526-j9kg00qf 3057 15 severity severity NN cord-022526-j9kg00qf 3057 16 of of IN cord-022526-j9kg00qf 3057 17 gastric gastric JJ cord-022526-j9kg00qf 3057 18 ulcers ulcer NNS cord-022526-j9kg00qf 3057 19 in in IN cord-022526-j9kg00qf 3057 20 Thoroughbreds Thoroughbreds NNPS cord-022526-j9kg00qf 3057 21 maintained maintain VBN cord-022526-j9kg00qf 3057 22 in in IN cord-022526-j9kg00qf 3057 23 race race NN cord-022526-j9kg00qf 3057 24 training training NN cord-022526-j9kg00qf 3057 25 . . . cord-022526-j9kg00qf 3058 1 70 70 CD cord-022526-j9kg00qf 3059 1 The the DT cord-022526-j9kg00qf 3059 2 available available JJ cord-022526-j9kg00qf 3059 3 equine equine JJ cord-022526-j9kg00qf 3059 4 preparation preparation NN cord-022526-j9kg00qf 3059 5 of of IN cord-022526-j9kg00qf 3059 6 omeprazole omeprazole NN cord-022526-j9kg00qf 3059 7 ( ( -LRB- cord-022526-j9kg00qf 3059 8 GastroGard GastroGard NNP cord-022526-j9kg00qf 3059 9 , , , cord-022526-j9kg00qf 3059 10 Merial Merial NNP cord-022526-j9kg00qf 3059 11 , , , cord-022526-j9kg00qf 3059 12 Ltd. Ltd. NNP cord-022526-j9kg00qf 3059 13 , , , cord-022526-j9kg00qf 3059 14 Duluth Duluth NNP cord-022526-j9kg00qf 3059 15 , , , cord-022526-j9kg00qf 3059 16 Georgia Georgia NNP cord-022526-j9kg00qf 3059 17 ) ) -RRB- cord-022526-j9kg00qf 3059 18 is be VBZ cord-022526-j9kg00qf 3059 19 recommended recommend VBN cord-022526-j9kg00qf 3059 20 at at IN cord-022526-j9kg00qf 3059 21 a a DT cord-022526-j9kg00qf 3059 22 dose dose NN cord-022526-j9kg00qf 3059 23 of of IN cord-022526-j9kg00qf 3059 24 4 4 CD cord-022526-j9kg00qf 3059 25 mg mg NNP cord-022526-j9kg00qf 3059 26 / / SYM cord-022526-j9kg00qf 3059 27 kg kg XX cord-022526-j9kg00qf 3059 28 orally orally RB cord-022526-j9kg00qf 3059 29 every every DT cord-022526-j9kg00qf 3059 30 24 24 CD cord-022526-j9kg00qf 3059 31 hours hour NNS cord-022526-j9kg00qf 3059 32 . . . cord-022526-j9kg00qf 3060 1 Initial initial JJ cord-022526-j9kg00qf 3060 2 reports report NNS cord-022526-j9kg00qf 3060 3 suggested suggest VBD cord-022526-j9kg00qf 3060 4 that that IN cord-022526-j9kg00qf 3060 5 3 3 CD cord-022526-j9kg00qf 3060 6 to to TO cord-022526-j9kg00qf 3060 7 5 5 CD cord-022526-j9kg00qf 3060 8 days day NNS cord-022526-j9kg00qf 3060 9 of of IN cord-022526-j9kg00qf 3060 10 omeprazole omeprazole NN cord-022526-j9kg00qf 3060 11 therapy therapy NN cord-022526-j9kg00qf 3060 12 were be VBD cord-022526-j9kg00qf 3060 13 necessary necessary JJ cord-022526-j9kg00qf 3060 14 to to TO cord-022526-j9kg00qf 3060 15 achieve achieve VB cord-022526-j9kg00qf 3060 16 maximum maximum JJ cord-022526-j9kg00qf 3060 17 acid acid NN cord-022526-j9kg00qf 3060 18 suppression suppression NN cord-022526-j9kg00qf 3060 19 ; ; : cord-022526-j9kg00qf 3060 20 however however RB cord-022526-j9kg00qf 3060 21 , , , cord-022526-j9kg00qf 3060 22 an an DT cord-022526-j9kg00qf 3060 23 increase increase NN cord-022526-j9kg00qf 3060 24 in in IN cord-022526-j9kg00qf 3060 25 gastric gastric JJ cord-022526-j9kg00qf 3060 26 pH ph NN cord-022526-j9kg00qf 3060 27 and and CC cord-022526-j9kg00qf 3060 28 a a DT cord-022526-j9kg00qf 3060 29 decrease decrease NN cord-022526-j9kg00qf 3060 30 in in IN cord-022526-j9kg00qf 3060 31 acid acid NN cord-022526-j9kg00qf 3060 32 output output NN cord-022526-j9kg00qf 3060 33 are be VBP cord-022526-j9kg00qf 3060 34 evident evident JJ cord-022526-j9kg00qf 3060 35 5 5 CD cord-022526-j9kg00qf 3060 36 to to TO cord-022526-j9kg00qf 3060 37 8 8 CD cord-022526-j9kg00qf 3060 38 hours hour NNS cord-022526-j9kg00qf 3060 39 after after IN cord-022526-j9kg00qf 3060 40 omeprazole omeprazole NNP cord-022526-j9kg00qf 3060 41 paste paste NNP cord-022526-j9kg00qf 3060 42 administration administration NNP cord-022526-j9kg00qf 3060 43 . . . cord-022526-j9kg00qf 3061 1 71 71 CD cord-022526-j9kg00qf 3062 1 After after IN cord-022526-j9kg00qf 3062 2 initial initial JJ cord-022526-j9kg00qf 3062 3 treatment treatment NN cord-022526-j9kg00qf 3062 4 ( ( -LRB- cord-022526-j9kg00qf 3062 5 28 28 CD cord-022526-j9kg00qf 3062 6 days day NNS cord-022526-j9kg00qf 3062 7 ) ) -RRB- cord-022526-j9kg00qf 3062 8 , , , cord-022526-j9kg00qf 3062 9 treatment treatment NN cord-022526-j9kg00qf 3062 10 with with IN cord-022526-j9kg00qf 3062 11 2 2 CD cord-022526-j9kg00qf 3062 12 or or CC cord-022526-j9kg00qf 3062 13 4 4 CD cord-022526-j9kg00qf 3062 14 mg mg NNP cord-022526-j9kg00qf 3062 15 / / SYM cord-022526-j9kg00qf 3062 16 kg kg NN cord-022526-j9kg00qf 3062 17 every every DT cord-022526-j9kg00qf 3062 18 24 24 CD cord-022526-j9kg00qf 3062 19 hours hour NNS cord-022526-j9kg00qf 3062 20 has have VBZ cord-022526-j9kg00qf 3062 21 been be VBN cord-022526-j9kg00qf 3062 22 shown show VBN cord-022526-j9kg00qf 3062 23 to to TO cord-022526-j9kg00qf 3062 24 decrease decrease VB cord-022526-j9kg00qf 3062 25 or or CC cord-022526-j9kg00qf 3062 26 prevent prevent VB cord-022526-j9kg00qf 3062 27 the the DT cord-022526-j9kg00qf 3062 28 recurrence recurrence NN cord-022526-j9kg00qf 3062 29 of of IN cord-022526-j9kg00qf 3062 30 disease disease NN cord-022526-j9kg00qf 3062 31 in in IN cord-022526-j9kg00qf 3062 32 animals animal NNS cord-022526-j9kg00qf 3062 33 maintained maintain VBN cord-022526-j9kg00qf 3062 34 in in IN cord-022526-j9kg00qf 3062 35 training training NN cord-022526-j9kg00qf 3062 36 . . . cord-022526-j9kg00qf 3063 1 72 72 CD cord-022526-j9kg00qf 3064 1 The the DT cord-022526-j9kg00qf 3064 2 powder powder NN cord-022526-j9kg00qf 3064 3 form form NN cord-022526-j9kg00qf 3064 4 of of IN cord-022526-j9kg00qf 3064 5 omeprazole omeprazole NN cord-022526-j9kg00qf 3064 6 degrades degrade VBZ cord-022526-j9kg00qf 3064 7 rapidly rapidly RB cord-022526-j9kg00qf 3064 8 in in IN cord-022526-j9kg00qf 3064 9 an an DT cord-022526-j9kg00qf 3064 10 acidic acidic JJ cord-022526-j9kg00qf 3064 11 environment environment NN cord-022526-j9kg00qf 3064 12 , , , cord-022526-j9kg00qf 3064 13 thus thus RB cord-022526-j9kg00qf 3064 14 one one PRP cord-022526-j9kg00qf 3064 15 must must MD cord-022526-j9kg00qf 3064 16 use use VB cord-022526-j9kg00qf 3064 17 an an DT cord-022526-j9kg00qf 3064 18 enteric enteric JJ cord-022526-j9kg00qf 3064 19 - - HYPH cord-022526-j9kg00qf 3064 20 coated coated JJ cord-022526-j9kg00qf 3064 21 capsule capsule NN cord-022526-j9kg00qf 3064 22 ( ( -LRB- cord-022526-j9kg00qf 3064 23 as as IN cord-022526-j9kg00qf 3064 24 used use VBN cord-022526-j9kg00qf 3064 25 in in IN cord-022526-j9kg00qf 3064 26 the the DT cord-022526-j9kg00qf 3064 27 human human JJ cord-022526-j9kg00qf 3064 28 preparation preparation NN cord-022526-j9kg00qf 3064 29 ) ) -RRB- cord-022526-j9kg00qf 3064 30 or or CC cord-022526-j9kg00qf 3064 31 a a DT cord-022526-j9kg00qf 3064 32 specially specially RB cord-022526-j9kg00qf 3064 33 formulated formulate VBN cord-022526-j9kg00qf 3064 34 paste paste NN cord-022526-j9kg00qf 3064 35 ( ( -LRB- cord-022526-j9kg00qf 3064 36 such such JJ cord-022526-j9kg00qf 3064 37 as as IN cord-022526-j9kg00qf 3064 38 GastroGard GastroGard NNP cord-022526-j9kg00qf 3064 39 ) ) -RRB- cord-022526-j9kg00qf 3064 40 to to TO cord-022526-j9kg00qf 3064 41 allow allow VB cord-022526-j9kg00qf 3064 42 delivery delivery NN cord-022526-j9kg00qf 3064 43 of of IN cord-022526-j9kg00qf 3064 44 the the DT cord-022526-j9kg00qf 3064 45 active active JJ cord-022526-j9kg00qf 3064 46 drug drug NN cord-022526-j9kg00qf 3064 47 to to IN cord-022526-j9kg00qf 3064 48 the the DT cord-022526-j9kg00qf 3064 49 small small JJ cord-022526-j9kg00qf 3064 50 intestine intestine NN cord-022526-j9kg00qf 3064 51 for for IN cord-022526-j9kg00qf 3064 52 absorption absorption NN cord-022526-j9kg00qf 3064 53 . . . cord-022526-j9kg00qf 3065 1 Many many JJ cord-022526-j9kg00qf 3065 2 compounding compound VBG cord-022526-j9kg00qf 3065 3 pharmacies pharmacy NNS cord-022526-j9kg00qf 3065 4 prepare prepare VBP cord-022526-j9kg00qf 3065 5 omeprazole omeprazole NN cord-022526-j9kg00qf 3065 6 in in IN cord-022526-j9kg00qf 3065 7 liquid liquid NN cord-022526-j9kg00qf 3065 8 or or CC cord-022526-j9kg00qf 3065 9 paste paste NN cord-022526-j9kg00qf 3065 10 formulation formulation NN cord-022526-j9kg00qf 3065 11 for for IN cord-022526-j9kg00qf 3065 12 use use NN cord-022526-j9kg00qf 3065 13 in in IN cord-022526-j9kg00qf 3065 14 horses horse NNS cord-022526-j9kg00qf 3065 15 , , , cord-022526-j9kg00qf 3065 16 but but CC cord-022526-j9kg00qf 3065 17 their -PRON- PRP$ cord-022526-j9kg00qf 3065 18 efficacy efficacy NN cord-022526-j9kg00qf 3065 19 has have VBZ cord-022526-j9kg00qf 3065 20 not not RB cord-022526-j9kg00qf 3065 21 been be VBN cord-022526-j9kg00qf 3065 22 evaluated evaluate VBN cord-022526-j9kg00qf 3065 23 to to IN cord-022526-j9kg00qf 3065 24 date date NN cord-022526-j9kg00qf 3065 25 . . . cord-022526-j9kg00qf 3066 1 Other other JJ cord-022526-j9kg00qf 3066 2 proton proton NN cord-022526-j9kg00qf 3066 3 pump pump NN cord-022526-j9kg00qf 3066 4 inhibitors inhibitor NNS cord-022526-j9kg00qf 3066 5 have have VBP cord-022526-j9kg00qf 3066 6 been be VBN cord-022526-j9kg00qf 3066 7 developed develop VBN cord-022526-j9kg00qf 3066 8 recently recently RB cord-022526-j9kg00qf 3066 9 for for IN cord-022526-j9kg00qf 3066 10 use use NN cord-022526-j9kg00qf 3066 11 in in IN cord-022526-j9kg00qf 3066 12 human human JJ cord-022526-j9kg00qf 3066 13 beings being NNS cord-022526-j9kg00qf 3066 14 , , , cord-022526-j9kg00qf 3066 15 including include VBG cord-022526-j9kg00qf 3066 16 rabeprazole rabeprazole NNP cord-022526-j9kg00qf 3066 17 , , , cord-022526-j9kg00qf 3066 18 lansoprazole lansoprazole NNP cord-022526-j9kg00qf 3066 19 , , , cord-022526-j9kg00qf 3066 20 esomeprazole esomeprazole NN cord-022526-j9kg00qf 3066 21 , , , cord-022526-j9kg00qf 3066 22 and and CC cord-022526-j9kg00qf 3066 23 pantoprazole pantoprazole NNP cord-022526-j9kg00qf 3066 24 . . . cord-022526-j9kg00qf 3067 1 In in IN cord-022526-j9kg00qf 3067 2 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 3067 3 reflux reflux NN cord-022526-j9kg00qf 3067 4 disease disease NN cord-022526-j9kg00qf 3067 5 treatment treatment NN cord-022526-j9kg00qf 3067 6 in in IN cord-022526-j9kg00qf 3067 7 human human JJ cord-022526-j9kg00qf 3067 8 beings being NNS cord-022526-j9kg00qf 3067 9 , , , cord-022526-j9kg00qf 3067 10 esomeprazole esomeprazole NNP cord-022526-j9kg00qf 3067 11 has have VBZ cord-022526-j9kg00qf 3067 12 demonstrated demonstrate VBN cord-022526-j9kg00qf 3067 13 a a DT cord-022526-j9kg00qf 3067 14 higher high JJR cord-022526-j9kg00qf 3067 15 rate rate NN cord-022526-j9kg00qf 3067 16 of of IN cord-022526-j9kg00qf 3067 17 healing healing NN cord-022526-j9kg00qf 3067 18 at at IN cord-022526-j9kg00qf 3067 19 4 4 CD cord-022526-j9kg00qf 3067 20 and and CC cord-022526-j9kg00qf 3067 21 8 8 CD cord-022526-j9kg00qf 3067 22 weeks week NNS cord-022526-j9kg00qf 3067 23 compared compare VBN cord-022526-j9kg00qf 3067 24 with with IN cord-022526-j9kg00qf 3067 25 omeprazole omeprazole NN cord-022526-j9kg00qf 3067 26 , , , cord-022526-j9kg00qf 3067 27 but but CC cord-022526-j9kg00qf 3067 28 rabeprazole rabeprazole NNP cord-022526-j9kg00qf 3067 29 , , , cord-022526-j9kg00qf 3067 30 lansoprazole lansoprazole NNP cord-022526-j9kg00qf 3067 31 , , , cord-022526-j9kg00qf 3067 32 and and CC cord-022526-j9kg00qf 3067 33 pantoprazole pantoprazole NNP cord-022526-j9kg00qf 3067 34 have have VBP cord-022526-j9kg00qf 3067 35 similar similar JJ cord-022526-j9kg00qf 3067 36 efficacy efficacy NN cord-022526-j9kg00qf 3067 37 . . . cord-022526-j9kg00qf 3068 1 73 73 CD cord-022526-j9kg00qf 3069 1 An an DT cord-022526-j9kg00qf 3069 2 intravenous intravenous JJ cord-022526-j9kg00qf 3069 3 formulation formulation NN cord-022526-j9kg00qf 3069 4 of of IN cord-022526-j9kg00qf 3069 5 pantoprazole pantoprazole NNP cord-022526-j9kg00qf 3069 6 recently recently RB cord-022526-j9kg00qf 3069 7 became become VBD cord-022526-j9kg00qf 3069 8 available available JJ cord-022526-j9kg00qf 3069 9 commercially commercially RB cord-022526-j9kg00qf 3069 10 and and CC cord-022526-j9kg00qf 3069 11 may may MD cord-022526-j9kg00qf 3069 12 prove prove VB cord-022526-j9kg00qf 3069 13 beneficial beneficial JJ cord-022526-j9kg00qf 3069 14 for for IN cord-022526-j9kg00qf 3069 15 patients patient NNS cord-022526-j9kg00qf 3069 16 in in IN cord-022526-j9kg00qf 3069 17 need need NN cord-022526-j9kg00qf 3069 18 of of IN cord-022526-j9kg00qf 3069 19 antiulcer antiulcer NNP cord-022526-j9kg00qf 3069 20 therapy therapy NN cord-022526-j9kg00qf 3069 21 that that WDT cord-022526-j9kg00qf 3069 22 can can MD cord-022526-j9kg00qf 3069 23 not not RB cord-022526-j9kg00qf 3069 24 be be VB cord-022526-j9kg00qf 3069 25 treated treat VBN cord-022526-j9kg00qf 3069 26 orally orally RB cord-022526-j9kg00qf 3069 27 . . . cord-022526-j9kg00qf 3070 1 Research research NN cord-022526-j9kg00qf 3070 2 regarding regard VBG cord-022526-j9kg00qf 3070 3 the the DT cord-022526-j9kg00qf 3070 4 pharmacokinetics pharmacokinetic NNS cord-022526-j9kg00qf 3070 5 and and CC cord-022526-j9kg00qf 3070 6 efficacy efficacy NN cord-022526-j9kg00qf 3070 7 of of IN cord-022526-j9kg00qf 3070 8 other other JJ cord-022526-j9kg00qf 3070 9 proton proton NN cord-022526-j9kg00qf 3070 10 pump pump NN cord-022526-j9kg00qf 3070 11 inhibitors inhibitor NNS cord-022526-j9kg00qf 3070 12 in in IN cord-022526-j9kg00qf 3070 13 horses horse NNS cord-022526-j9kg00qf 3070 14 is be VBZ cord-022526-j9kg00qf 3070 15 not not RB cord-022526-j9kg00qf 3070 16 currently currently RB cord-022526-j9kg00qf 3070 17 available available JJ cord-022526-j9kg00qf 3070 18 . . . cord-022526-j9kg00qf 3071 1 Sucralfate sucralfate NN cord-022526-j9kg00qf 3071 2 is be VBZ cord-022526-j9kg00qf 3071 3 effective effective JJ cord-022526-j9kg00qf 3071 4 in in IN cord-022526-j9kg00qf 3071 5 treating treat VBG cord-022526-j9kg00qf 3071 6 peptic peptic JJ cord-022526-j9kg00qf 3071 7 ulcers ulcer NNS cord-022526-j9kg00qf 3071 8 and and CC cord-022526-j9kg00qf 3071 9 preventing prevent VBG cord-022526-j9kg00qf 3071 10 stress stress NN cord-022526-j9kg00qf 3071 11 - - HYPH cord-022526-j9kg00qf 3071 12 induced induce VBN cord-022526-j9kg00qf 3071 13 ulcers ulcer NNS cord-022526-j9kg00qf 3071 14 in in IN cord-022526-j9kg00qf 3071 15 human human JJ cord-022526-j9kg00qf 3071 16 beings being NNS cord-022526-j9kg00qf 3071 17 . . . cord-022526-j9kg00qf 3072 1 The the DT cord-022526-j9kg00qf 3072 2 mechanism mechanism NN cord-022526-j9kg00qf 3072 3 of of IN cord-022526-j9kg00qf 3072 4 action action NN cord-022526-j9kg00qf 3072 5 likely likely RB cord-022526-j9kg00qf 3072 6 involves involve VBZ cord-022526-j9kg00qf 3072 7 adherence adherence NN cord-022526-j9kg00qf 3072 8 to to IN cord-022526-j9kg00qf 3072 9 ulcerated ulcerated JJ cord-022526-j9kg00qf 3072 10 mucosa mucosa JJ cord-022526-j9kg00qf 3072 11 , , , cord-022526-j9kg00qf 3072 12 stimulation stimulation NN cord-022526-j9kg00qf 3072 13 of of IN cord-022526-j9kg00qf 3072 14 mucus mucus NN cord-022526-j9kg00qf 3072 15 secretion secretion NN cord-022526-j9kg00qf 3072 16 , , , cord-022526-j9kg00qf 3072 17 enhanced enhance VBN cord-022526-j9kg00qf 3072 18 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3072 19 E e NN cord-022526-j9kg00qf 3072 20 synthesis synthesis NN cord-022526-j9kg00qf 3072 21 , , , cord-022526-j9kg00qf 3072 22 and and CC cord-022526-j9kg00qf 3072 23 increased increase VBN cord-022526-j9kg00qf 3072 24 concentration concentration NN cord-022526-j9kg00qf 3072 25 of of IN cord-022526-j9kg00qf 3072 26 growth growth NN cord-022526-j9kg00qf 3072 27 factor factor NN cord-022526-j9kg00qf 3072 28 at at IN cord-022526-j9kg00qf 3072 29 the the DT cord-022526-j9kg00qf 3072 30 site site NN cord-022526-j9kg00qf 3072 31 of of IN cord-022526-j9kg00qf 3072 32 ulceration ulceration NN cord-022526-j9kg00qf 3072 33 , , , cord-022526-j9kg00qf 3072 34 although although IN cord-022526-j9kg00qf 3072 35 the the DT cord-022526-j9kg00qf 3072 36 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3072 37 effects effect NNS cord-022526-j9kg00qf 3072 38 may may MD cord-022526-j9kg00qf 3072 39 not not RB cord-022526-j9kg00qf 3072 40 play play VB cord-022526-j9kg00qf 3072 41 an an DT cord-022526-j9kg00qf 3072 42 important important JJ cord-022526-j9kg00qf 3072 43 role role NN cord-022526-j9kg00qf 3072 44 in in IN cord-022526-j9kg00qf 3072 45 ulcer ulcer NN cord-022526-j9kg00qf 3072 46 healing healing NN cord-022526-j9kg00qf 3072 47 . . . cord-022526-j9kg00qf 3073 1 74 74 CD cord-022526-j9kg00qf 3074 1 These these DT cord-022526-j9kg00qf 3074 2 are be VBP cord-022526-j9kg00qf 3074 3 factors factor NNS cord-022526-j9kg00qf 3074 4 relevant relevant JJ cord-022526-j9kg00qf 3074 5 to to IN cord-022526-j9kg00qf 3074 6 glandular glandular JJ cord-022526-j9kg00qf 3074 7 mucosa mucosa NN cord-022526-j9kg00qf 3074 8 , , , cord-022526-j9kg00qf 3074 9 and and CC cord-022526-j9kg00qf 3074 10 the the DT cord-022526-j9kg00qf 3074 11 efficacy efficacy NN cord-022526-j9kg00qf 3074 12 of of IN cord-022526-j9kg00qf 3074 13 sucralfate sucralfate NN cord-022526-j9kg00qf 3074 14 in in IN cord-022526-j9kg00qf 3074 15 treating treat VBG cord-022526-j9kg00qf 3074 16 ulcers ulcer NNS cord-022526-j9kg00qf 3074 17 in in IN cord-022526-j9kg00qf 3074 18 the the DT cord-022526-j9kg00qf 3074 19 equine equine JJ cord-022526-j9kg00qf 3074 20 gastric gastric JJ cord-022526-j9kg00qf 3074 21 squamous squamous JJ cord-022526-j9kg00qf 3074 22 mucosa mucosa NN cord-022526-j9kg00qf 3074 23 remains remain VBZ cord-022526-j9kg00qf 3074 24 undetermined undetermined JJ cord-022526-j9kg00qf 3074 25 . . . cord-022526-j9kg00qf 3075 1 Sucralfate Sucralfate NNP cord-022526-j9kg00qf 3075 2 may may MD cord-022526-j9kg00qf 3075 3 be be VB cord-022526-j9kg00qf 3075 4 effective effective JJ cord-022526-j9kg00qf 3075 5 in in IN cord-022526-j9kg00qf 3075 6 preventing prevent VBG cord-022526-j9kg00qf 3075 7 stress stress NN cord-022526-j9kg00qf 3075 8 - - HYPH cord-022526-j9kg00qf 3075 9 induced induce VBN cord-022526-j9kg00qf 3075 10 ulcers ulcer NNS cord-022526-j9kg00qf 3075 11 in in IN cord-022526-j9kg00qf 3075 12 neonatal neonatal JJ cord-022526-j9kg00qf 3075 13 foals foal NNS cord-022526-j9kg00qf 3075 14 , , , cord-022526-j9kg00qf 3075 15 because because IN cord-022526-j9kg00qf 3075 16 these these DT cord-022526-j9kg00qf 3075 17 occur occur VBP cord-022526-j9kg00qf 3075 18 in in IN cord-022526-j9kg00qf 3075 19 the the DT cord-022526-j9kg00qf 3075 20 glandular glandular JJ cord-022526-j9kg00qf 3075 21 mucosa mucosa NN cord-022526-j9kg00qf 3075 22 , , , cord-022526-j9kg00qf 3075 23 although although IN cord-022526-j9kg00qf 3075 24 no no DT cord-022526-j9kg00qf 3075 25 clinical clinical JJ cord-022526-j9kg00qf 3075 26 evidence evidence NN cord-022526-j9kg00qf 3075 27 directly directly RB cord-022526-j9kg00qf 3075 28 supports support VBZ cord-022526-j9kg00qf 3075 29 this this DT cord-022526-j9kg00qf 3075 30 concept concept NN cord-022526-j9kg00qf 3075 31 . . . cord-022526-j9kg00qf 3076 1 In in IN cord-022526-j9kg00qf 3076 2 human human JJ cord-022526-j9kg00qf 3076 3 beings being NNS cord-022526-j9kg00qf 3076 4 , , , cord-022526-j9kg00qf 3076 5 sucralfate sucralfate NNP cord-022526-j9kg00qf 3076 6 provides provide VBZ cord-022526-j9kg00qf 3076 7 protection protection NN cord-022526-j9kg00qf 3076 8 against against IN cord-022526-j9kg00qf 3076 9 stress stress NN cord-022526-j9kg00qf 3076 10 - - HYPH cord-022526-j9kg00qf 3076 11 induced induce VBN cord-022526-j9kg00qf 3076 12 ulcers ulcer NNS cord-022526-j9kg00qf 3076 13 with with IN cord-022526-j9kg00qf 3076 14 a a DT cord-022526-j9kg00qf 3076 15 decreased decreased JJ cord-022526-j9kg00qf 3076 16 risk risk NN cord-022526-j9kg00qf 3076 17 of of IN cord-022526-j9kg00qf 3076 18 pathogenic pathogenic JJ cord-022526-j9kg00qf 3076 19 gastric gastric JJ cord-022526-j9kg00qf 3076 20 colonization colonization NN cord-022526-j9kg00qf 3076 21 . . . cord-022526-j9kg00qf 3077 1 75 75 CD cord-022526-j9kg00qf 3077 2 One one PRP cord-022526-j9kg00qf 3077 3 should should MD cord-022526-j9kg00qf 3077 4 give give VB cord-022526-j9kg00qf 3077 5 sucralfate sucralfate NN cord-022526-j9kg00qf 3077 6 at at IN cord-022526-j9kg00qf 3077 7 a a DT cord-022526-j9kg00qf 3077 8 dosage dosage NN cord-022526-j9kg00qf 3077 9 of of IN cord-022526-j9kg00qf 3077 10 10 10 CD cord-022526-j9kg00qf 3077 11 to to TO cord-022526-j9kg00qf 3077 12 20 20 CD cord-022526-j9kg00qf 3077 13 mg mg NNP cord-022526-j9kg00qf 3077 14 / / SYM cord-022526-j9kg00qf 3077 15 kg kg NNP cord-022526-j9kg00qf 3077 16 every every DT cord-022526-j9kg00qf 3077 17 6 6 CD cord-022526-j9kg00qf 3077 18 to to TO cord-022526-j9kg00qf 3077 19 8 8 CD cord-022526-j9kg00qf 3077 20 hours hour NNS cord-022526-j9kg00qf 3077 21 . . . cord-022526-j9kg00qf 3078 1 The the DT cord-022526-j9kg00qf 3078 2 efficacy efficacy NN cord-022526-j9kg00qf 3078 3 of of IN cord-022526-j9kg00qf 3078 4 sucralfate sucralfate NN cord-022526-j9kg00qf 3078 5 in in IN cord-022526-j9kg00qf 3078 6 an an DT cord-022526-j9kg00qf 3078 7 alkaline alkaline JJ cord-022526-j9kg00qf 3078 8 pH ph NN cord-022526-j9kg00qf 3078 9 is be VBZ cord-022526-j9kg00qf 3078 10 controversial controversial JJ cord-022526-j9kg00qf 3078 11 but but CC cord-022526-j9kg00qf 3078 12 appears appear VBZ cord-022526-j9kg00qf 3078 13 likely likely JJ cord-022526-j9kg00qf 3078 14 . . . cord-022526-j9kg00qf 3079 1 [ [ -LRB- cord-022526-j9kg00qf 3079 2 76 76 CD cord-022526-j9kg00qf 3079 3 ] ] -RRB- cord-022526-j9kg00qf 3079 4 [ [ -LRB- cord-022526-j9kg00qf 3079 5 77 77 CD cord-022526-j9kg00qf 3079 6 ] ] -RRB- cord-022526-j9kg00qf 3080 1 [ [ -LRB- cord-022526-j9kg00qf 3080 2 78 78 CD cord-022526-j9kg00qf 3080 3 ] ] -RRB- cord-022526-j9kg00qf 3081 1 Moreover moreover RB cord-022526-j9kg00qf 3081 2 , , , cord-022526-j9kg00qf 3081 3 at at IN cord-022526-j9kg00qf 3081 4 the the DT cord-022526-j9kg00qf 3081 5 time time NN cord-022526-j9kg00qf 3081 6 of of IN cord-022526-j9kg00qf 3081 7 administration administration NN cord-022526-j9kg00qf 3081 8 of of IN cord-022526-j9kg00qf 3081 9 an an DT cord-022526-j9kg00qf 3081 10 SECTION section NN cord-022526-j9kg00qf 3081 11 13 13 CD cord-022526-j9kg00qf 3081 12 . . . cord-022526-j9kg00qf 3082 1 10 10 CD cord-022526-j9kg00qf 3082 2 Diseases disease NNS cord-022526-j9kg00qf 3082 3 of of IN cord-022526-j9kg00qf 3082 4 the the DT cord-022526-j9kg00qf 3082 5 Stomach Stomach NNP cord-022526-j9kg00qf 3082 6 H H NNP cord-022526-j9kg00qf 3082 7 2 2 CD cord-022526-j9kg00qf 3082 8 antagonist antagonist NN cord-022526-j9kg00qf 3082 9 , , , cord-022526-j9kg00qf 3082 10 the the DT cord-022526-j9kg00qf 3082 11 gastric gastric JJ cord-022526-j9kg00qf 3082 12 pH pH NNP cord-022526-j9kg00qf 3082 13 likely likely RB cord-022526-j9kg00qf 3082 14 will will MD cord-022526-j9kg00qf 3082 15 have have VB cord-022526-j9kg00qf 3082 16 returned return VBN cord-022526-j9kg00qf 3082 17 to to IN cord-022526-j9kg00qf 3082 18 an an DT cord-022526-j9kg00qf 3082 19 acidic acidic JJ cord-022526-j9kg00qf 3082 20 pH ph NN cord-022526-j9kg00qf 3082 21 since since IN cord-022526-j9kg00qf 3082 22 the the DT cord-022526-j9kg00qf 3082 23 last last JJ cord-022526-j9kg00qf 3082 24 dosage dosage NN cord-022526-j9kg00qf 3082 25 and and CC cord-022526-j9kg00qf 3082 26 will will MD cord-022526-j9kg00qf 3082 27 remain remain VB cord-022526-j9kg00qf 3082 28 so so RB cord-022526-j9kg00qf 3082 29 for for IN cord-022526-j9kg00qf 3082 30 30 30 CD cord-022526-j9kg00qf 3082 31 to to TO cord-022526-j9kg00qf 3082 32 60 60 CD cord-022526-j9kg00qf 3082 33 minutes minute NNS cord-022526-j9kg00qf 3082 34 depending depend VBG cord-022526-j9kg00qf 3082 35 on on IN cord-022526-j9kg00qf 3082 36 the the DT cord-022526-j9kg00qf 3082 37 route route NN cord-022526-j9kg00qf 3082 38 of of IN cord-022526-j9kg00qf 3082 39 administration administration NN cord-022526-j9kg00qf 3082 40 ; ; : cord-022526-j9kg00qf 3082 41 thus thus RB cord-022526-j9kg00qf 3082 42 one one CD cord-022526-j9kg00qf 3082 43 likely likely RB cord-022526-j9kg00qf 3082 44 can can MD cord-022526-j9kg00qf 3082 45 administer administer VB cord-022526-j9kg00qf 3082 46 the the DT cord-022526-j9kg00qf 3082 47 agents agent NNS cord-022526-j9kg00qf 3082 48 simultaneously simultaneously RB cord-022526-j9kg00qf 3082 49 if if IN cord-022526-j9kg00qf 3082 50 so so RB cord-022526-j9kg00qf 3082 51 desired desire VBN cord-022526-j9kg00qf 3082 52 . . . cord-022526-j9kg00qf 3083 1 The the DT cord-022526-j9kg00qf 3083 2 use use NN cord-022526-j9kg00qf 3083 3 of of IN cord-022526-j9kg00qf 3083 4 antacids antacid NNS cord-022526-j9kg00qf 3083 5 to to TO cord-022526-j9kg00qf 3083 6 treat treat VB cord-022526-j9kg00qf 3083 7 gastric gastric JJ cord-022526-j9kg00qf 3083 8 ulcers ulcer NNS cord-022526-j9kg00qf 3083 9 has have VBZ cord-022526-j9kg00qf 3083 10 not not RB cord-022526-j9kg00qf 3083 11 been be VBN cord-022526-j9kg00qf 3083 12 examined examine VBN cord-022526-j9kg00qf 3083 13 critically critically RB cord-022526-j9kg00qf 3083 14 in in IN cord-022526-j9kg00qf 3083 15 the the DT cord-022526-j9kg00qf 3083 16 horse horse NN cord-022526-j9kg00qf 3083 17 . . . cord-022526-j9kg00qf 3084 1 Research research NN cord-022526-j9kg00qf 3084 2 in in IN cord-022526-j9kg00qf 3084 3 horses horse NNS cord-022526-j9kg00qf 3084 4 has have VBZ cord-022526-j9kg00qf 3084 5 shown show VBN cord-022526-j9kg00qf 3084 6 that that IN cord-022526-j9kg00qf 3084 7 30 30 CD cord-022526-j9kg00qf 3084 8 g g NN cord-022526-j9kg00qf 3084 9 aluminum aluminum NN cord-022526-j9kg00qf 3084 10 hydroxide hydroxide NN cord-022526-j9kg00qf 3084 11 per per IN cord-022526-j9kg00qf 3084 12 15 15 CD cord-022526-j9kg00qf 3084 13 g g NN cord-022526-j9kg00qf 3084 14 magnesium magnesium NN cord-022526-j9kg00qf 3084 15 hydroxide hydroxide NN cord-022526-j9kg00qf 3084 16 results result NNS cord-022526-j9kg00qf 3084 17 in in IN cord-022526-j9kg00qf 3084 18 an an DT cord-022526-j9kg00qf 3084 19 increase increase NN cord-022526-j9kg00qf 3084 20 in in IN cord-022526-j9kg00qf 3084 21 gastric gastric JJ cord-022526-j9kg00qf 3084 22 pH ph NN cord-022526-j9kg00qf 3084 23 above above IN cord-022526-j9kg00qf 3084 24 4 4 CD cord-022526-j9kg00qf 3084 25 for for IN cord-022526-j9kg00qf 3084 26 approximately approximately RB cord-022526-j9kg00qf 3084 27 2 2 CD cord-022526-j9kg00qf 3084 28 hours hour NNS cord-022526-j9kg00qf 3084 29 . . . cord-022526-j9kg00qf 3085 1 79 79 CD cord-022526-j9kg00qf 3086 1 Thus thus RB cord-022526-j9kg00qf 3086 2 although although IN cord-022526-j9kg00qf 3086 3 antacids antacid NNS cord-022526-j9kg00qf 3086 4 may may MD cord-022526-j9kg00qf 3086 5 be be VB cord-022526-j9kg00qf 3086 6 useful useful JJ cord-022526-j9kg00qf 3086 7 for for IN cord-022526-j9kg00qf 3086 8 treating treat VBG cord-022526-j9kg00qf 3086 9 ulcers ulcer NNS cord-022526-j9kg00qf 3086 10 in in IN cord-022526-j9kg00qf 3086 11 horses horse NNS cord-022526-j9kg00qf 3086 12 , , , cord-022526-j9kg00qf 3086 13 a a DT cord-022526-j9kg00qf 3086 14 dose dose NN cord-022526-j9kg00qf 3086 15 of of IN cord-022526-j9kg00qf 3086 16 approximately approximately RB cord-022526-j9kg00qf 3086 17 180 180 CD cord-022526-j9kg00qf 3086 18 to to TO cord-022526-j9kg00qf 3086 19 200 200 CD cord-022526-j9kg00qf 3086 20 ml ml NNS cord-022526-j9kg00qf 3086 21 at at IN cord-022526-j9kg00qf 3086 22 least least JJS cord-022526-j9kg00qf 3086 23 every every DT cord-022526-j9kg00qf 3086 24 4 4 CD cord-022526-j9kg00qf 3086 25 hours hour NNS cord-022526-j9kg00qf 3086 26 is be VBZ cord-022526-j9kg00qf 3086 27 necessary necessary JJ cord-022526-j9kg00qf 3086 28 for for IN cord-022526-j9kg00qf 3086 29 a a DT cord-022526-j9kg00qf 3086 30 standard standard JJ cord-022526-j9kg00qf 3086 31 adult adult NN cord-022526-j9kg00qf 3086 32 horse horse NN cord-022526-j9kg00qf 3086 33 . . . cord-022526-j9kg00qf 3087 1 The the DT cord-022526-j9kg00qf 3087 2 use use NN cord-022526-j9kg00qf 3087 3 of of IN cord-022526-j9kg00qf 3087 4 synthetic synthetic JJ cord-022526-j9kg00qf 3087 5 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3087 6 E e NN cord-022526-j9kg00qf 3087 7 1 1 CD cord-022526-j9kg00qf 3087 8 analogs analog NNS cord-022526-j9kg00qf 3087 9 , , , cord-022526-j9kg00qf 3087 10 such such JJ cord-022526-j9kg00qf 3087 11 as as IN cord-022526-j9kg00qf 3087 12 misoprostol misoprostol NNP cord-022526-j9kg00qf 3087 13 , , , cord-022526-j9kg00qf 3087 14 has have VBZ cord-022526-j9kg00qf 3087 15 been be VBN cord-022526-j9kg00qf 3087 16 effective effective JJ cord-022526-j9kg00qf 3087 17 in in IN cord-022526-j9kg00qf 3087 18 treating treat VBG cord-022526-j9kg00qf 3087 19 gastric gastric JJ cord-022526-j9kg00qf 3087 20 and and CC cord-022526-j9kg00qf 3087 21 duodenal duodenal JJ cord-022526-j9kg00qf 3087 22 ulcers ulcer NNS cord-022526-j9kg00qf 3087 23 in in IN cord-022526-j9kg00qf 3087 24 human human JJ cord-022526-j9kg00qf 3087 25 beings being NNS cord-022526-j9kg00qf 3087 26 , , , cord-022526-j9kg00qf 3087 27 and and CC cord-022526-j9kg00qf 3087 28 the the DT cord-022526-j9kg00qf 3087 29 proposed propose VBN cord-022526-j9kg00qf 3087 30 mechanism mechanism NN cord-022526-j9kg00qf 3087 31 of of IN cord-022526-j9kg00qf 3087 32 action action NN cord-022526-j9kg00qf 3087 33 involves involve VBZ cord-022526-j9kg00qf 3087 34 inhibition inhibition NN cord-022526-j9kg00qf 3087 35 of of IN cord-022526-j9kg00qf 3087 36 gastric gastric JJ cord-022526-j9kg00qf 3087 37 acid acid NN cord-022526-j9kg00qf 3087 38 secretion secretion NN cord-022526-j9kg00qf 3087 39 and and CC cord-022526-j9kg00qf 3087 40 mucosal mucosal JJ cord-022526-j9kg00qf 3087 41 cytoprotection cytoprotection NN cord-022526-j9kg00qf 3087 42 . . . cord-022526-j9kg00qf 3088 1 80 80 CD cord-022526-j9kg00qf 3088 2 Frequently frequently RB cord-022526-j9kg00qf 3088 3 reported report VBD cord-022526-j9kg00qf 3088 4 adverse adverse JJ cord-022526-j9kg00qf 3088 5 effects effect NNS cord-022526-j9kg00qf 3088 6 of of IN cord-022526-j9kg00qf 3088 7 intestinal intestinal JJ cord-022526-j9kg00qf 3088 8 cramping cramping NN cord-022526-j9kg00qf 3088 9 and and CC cord-022526-j9kg00qf 3088 10 diarrhea diarrhea NN cord-022526-j9kg00qf 3088 11 in in IN cord-022526-j9kg00qf 3088 12 human human JJ cord-022526-j9kg00qf 3088 13 beings being NNS cord-022526-j9kg00qf 3088 14 have have VBP cord-022526-j9kg00qf 3088 15 precluded preclude VBN cord-022526-j9kg00qf 3088 16 the the DT cord-022526-j9kg00qf 3088 17 use use NN cord-022526-j9kg00qf 3088 18 of of IN cord-022526-j9kg00qf 3088 19 misoprostol misoprostol NNP cord-022526-j9kg00qf 3088 20 in in IN cord-022526-j9kg00qf 3088 21 horses horse NNS cord-022526-j9kg00qf 3088 22 . . . cord-022526-j9kg00qf 3089 1 One one PRP cord-022526-j9kg00qf 3089 2 should should MD cord-022526-j9kg00qf 3089 3 consider consider VB cord-022526-j9kg00qf 3089 4 prokinetic prokinetic JJ cord-022526-j9kg00qf 3089 5 drugs drug NNS cord-022526-j9kg00qf 3089 6 in in IN cord-022526-j9kg00qf 3089 7 foals foal NNS cord-022526-j9kg00qf 3089 8 with with IN cord-022526-j9kg00qf 3089 9 duodenal duodenal JJ cord-022526-j9kg00qf 3089 10 disease disease NN cord-022526-j9kg00qf 3089 11 and and CC cord-022526-j9kg00qf 3089 12 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 3089 13 reflux reflux NN cord-022526-j9kg00qf 3089 14 and and CC cord-022526-j9kg00qf 3089 15 when when WRB cord-022526-j9kg00qf 3089 16 one one CD cord-022526-j9kg00qf 3089 17 suspects suspect NNS cord-022526-j9kg00qf 3089 18 delayed delay VBD cord-022526-j9kg00qf 3089 19 gastric gastric JJ cord-022526-j9kg00qf 3089 20 emptying emptying NN cord-022526-j9kg00qf 3089 21 without without IN cord-022526-j9kg00qf 3089 22 a a DT cord-022526-j9kg00qf 3089 23 physical physical JJ cord-022526-j9kg00qf 3089 24 obstruction obstruction NN cord-022526-j9kg00qf 3089 25 . . . cord-022526-j9kg00qf 3090 1 The the DT cord-022526-j9kg00qf 3090 2 cholinergic cholinergic JJ cord-022526-j9kg00qf 3090 3 drug drug NN cord-022526-j9kg00qf 3090 4 bethanechol bethanechol NNP cord-022526-j9kg00qf 3090 5 has have VBZ cord-022526-j9kg00qf 3090 6 been be VBN cord-022526-j9kg00qf 3090 7 shown show VBN cord-022526-j9kg00qf 3090 8 to to TO cord-022526-j9kg00qf 3090 9 increase increase VB cord-022526-j9kg00qf 3090 10 the the DT cord-022526-j9kg00qf 3090 11 rate rate NN cord-022526-j9kg00qf 3090 12 of of IN cord-022526-j9kg00qf 3090 13 gastric gastric JJ cord-022526-j9kg00qf 3090 14 emptying emptying NN cord-022526-j9kg00qf 3090 15 in in IN cord-022526-j9kg00qf 3090 16 horses horse NNS cord-022526-j9kg00qf 3090 17 . . . cord-022526-j9kg00qf 3091 1 81 81 CD cord-022526-j9kg00qf 3092 1 In in IN cord-022526-j9kg00qf 3092 2 cases case NNS cord-022526-j9kg00qf 3092 3 of of IN cord-022526-j9kg00qf 3092 4 acute acute JJ cord-022526-j9kg00qf 3092 5 gastric gastric JJ cord-022526-j9kg00qf 3092 6 atony atony NN cord-022526-j9kg00qf 3092 7 , , , cord-022526-j9kg00qf 3092 8 bethanechol bethanechol NNP cord-022526-j9kg00qf 3092 9 0.025 0.025 CD cord-022526-j9kg00qf 3092 10 to to IN cord-022526-j9kg00qf 3092 11 0.030 0.030 CD cord-022526-j9kg00qf 3092 12 mg mg NN cord-022526-j9kg00qf 3092 13 / / SYM cord-022526-j9kg00qf 3092 14 kg kg NNS cord-022526-j9kg00qf 3092 15 administered administer VBD cord-022526-j9kg00qf 3092 16 subcutaneously subcutaneously RB cord-022526-j9kg00qf 3092 17 every every DT cord-022526-j9kg00qf 3092 18 3 3 CD cord-022526-j9kg00qf 3092 19 to to TO cord-022526-j9kg00qf 3092 20 4 4 CD cord-022526-j9kg00qf 3092 21 hours hour NNS cord-022526-j9kg00qf 3092 22 has have VBZ cord-022526-j9kg00qf 3092 23 been be VBN cord-022526-j9kg00qf 3092 24 effective effective JJ cord-022526-j9kg00qf 3092 25 in in IN cord-022526-j9kg00qf 3092 26 promoting promote VBG cord-022526-j9kg00qf 3092 27 gastric gastric JJ cord-022526-j9kg00qf 3092 28 motility motility NN cord-022526-j9kg00qf 3092 29 and and CC cord-022526-j9kg00qf 3092 30 emptying emptying NN cord-022526-j9kg00qf 3092 31 , , , cord-022526-j9kg00qf 3092 32 followed follow VBN cord-022526-j9kg00qf 3092 33 by by IN cord-022526-j9kg00qf 3092 34 oral oral JJ cord-022526-j9kg00qf 3092 35 maintenance maintenance NN cord-022526-j9kg00qf 3092 36 dosages dosage NNS cord-022526-j9kg00qf 3092 37 of of IN cord-022526-j9kg00qf 3092 38 0.35 0.35 CD cord-022526-j9kg00qf 3092 39 to to TO cord-022526-j9kg00qf 3092 40 0.45 0.45 CD cord-022526-j9kg00qf 3092 41 mg mg NNP cord-022526-j9kg00qf 3092 42 / / SYM cord-022526-j9kg00qf 3092 43 kg kg NNP cord-022526-j9kg00qf 3092 44 3 3 CD cord-022526-j9kg00qf 3092 45 to to IN cord-022526-j9kg00qf 3092 46 4 4 CD cord-022526-j9kg00qf 3092 47 times time NNS cord-022526-j9kg00qf 3092 48 daily daily RB cord-022526-j9kg00qf 3092 49 . . . cord-022526-j9kg00qf 3093 1 Adverse adverse JJ cord-022526-j9kg00qf 3093 2 effects effect NNS cord-022526-j9kg00qf 3093 3 can can MD cord-022526-j9kg00qf 3093 4 include include VB cord-022526-j9kg00qf 3093 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3093 6 , , , cord-022526-j9kg00qf 3093 7 inappetance inappetance NN cord-022526-j9kg00qf 3093 8 , , , cord-022526-j9kg00qf 3093 9 salivation salivation NN cord-022526-j9kg00qf 3093 10 , , , cord-022526-j9kg00qf 3093 11 and and CC cord-022526-j9kg00qf 3093 12 colic colic NN cord-022526-j9kg00qf 3093 13 , , , cord-022526-j9kg00qf 3093 14 but but CC cord-022526-j9kg00qf 3093 15 at at IN cord-022526-j9kg00qf 3093 16 the the DT cord-022526-j9kg00qf 3093 17 dosages dosage NNS cord-022526-j9kg00qf 3093 18 stated state VBN cord-022526-j9kg00qf 3093 19 , , , cord-022526-j9kg00qf 3093 20 adverse adverse JJ cord-022526-j9kg00qf 3093 21 effects effect NNS cord-022526-j9kg00qf 3093 22 have have VBP cord-022526-j9kg00qf 3093 23 been be VBN cord-022526-j9kg00qf 3093 24 infrequent infrequent JJ cord-022526-j9kg00qf 3093 25 and and CC cord-022526-j9kg00qf 3093 26 mild mild JJ cord-022526-j9kg00qf 3093 27 . . . cord-022526-j9kg00qf 3094 1 A a DT cord-022526-j9kg00qf 3094 2 complete complete JJ cord-022526-j9kg00qf 3094 3 review review NN cord-022526-j9kg00qf 3094 4 of of IN cord-022526-j9kg00qf 3094 5 ileus ileus NNP cord-022526-j9kg00qf 3094 6 and and CC cord-022526-j9kg00qf 3094 7 prokinetic prokinetic JJ cord-022526-j9kg00qf 3094 8 therapy therapy NN cord-022526-j9kg00qf 3094 9 is be VBZ cord-022526-j9kg00qf 3094 10 available available JJ cord-022526-j9kg00qf 3094 11 in in IN cord-022526-j9kg00qf 3094 12 Chapter chapter NN cord-022526-j9kg00qf 3094 13 13.6 13.6 CD cord-022526-j9kg00qf 3094 14 . . . cord-022526-j9kg00qf 3095 1 For for IN cord-022526-j9kg00qf 3095 2 foals foal NNS cord-022526-j9kg00qf 3095 3 with with IN cord-022526-j9kg00qf 3095 4 severe severe JJ cord-022526-j9kg00qf 3095 5 gastroduodenal gastroduodenal JJ cord-022526-j9kg00qf 3095 6 ulcer ulcer NN cord-022526-j9kg00qf 3095 7 disease disease NN cord-022526-j9kg00qf 3095 8 that that WDT cord-022526-j9kg00qf 3095 9 have have VBP cord-022526-j9kg00qf 3095 10 developed develop VBN cord-022526-j9kg00qf 3095 11 duodenal duodenal JJ cord-022526-j9kg00qf 3095 12 stricture stricture NN cord-022526-j9kg00qf 3095 13 , , , cord-022526-j9kg00qf 3095 14 surgical surgical JJ cord-022526-j9kg00qf 3095 15 therapy therapy NN cord-022526-j9kg00qf 3095 16 is be VBZ cord-022526-j9kg00qf 3095 17 necessary necessary JJ cord-022526-j9kg00qf 3095 18 . . . cord-022526-j9kg00qf 3096 1 57 57 CD cord-022526-j9kg00qf 3096 2 , , , cord-022526-j9kg00qf 3096 3 82 82 CD cord-022526-j9kg00qf 3096 4 These these DT cord-022526-j9kg00qf 3096 5 animals animal NNS cord-022526-j9kg00qf 3096 6 require require VBP cord-022526-j9kg00qf 3096 7 a a DT cord-022526-j9kg00qf 3096 8 serious serious JJ cord-022526-j9kg00qf 3096 9 financial financial JJ cord-022526-j9kg00qf 3096 10 commitment commitment NN cord-022526-j9kg00qf 3096 11 because because IN cord-022526-j9kg00qf 3096 12 intensive intensive JJ cord-022526-j9kg00qf 3096 13 perioperative perioperative JJ cord-022526-j9kg00qf 3096 14 medical medical JJ cord-022526-j9kg00qf 3096 15 therapy therapy NN cord-022526-j9kg00qf 3096 16 is be VBZ cord-022526-j9kg00qf 3096 17 critical critical JJ cord-022526-j9kg00qf 3096 18 for for IN cord-022526-j9kg00qf 3096 19 a a DT cord-022526-j9kg00qf 3096 20 successful successful JJ cord-022526-j9kg00qf 3096 21 outcome outcome NN cord-022526-j9kg00qf 3096 22 . . . cord-022526-j9kg00qf 3097 1 Even even RB cord-022526-j9kg00qf 3097 2 with with IN cord-022526-j9kg00qf 3097 3 surgical surgical JJ cord-022526-j9kg00qf 3097 4 therapy therapy NN cord-022526-j9kg00qf 3097 5 , , , cord-022526-j9kg00qf 3097 6 these these DT cord-022526-j9kg00qf 3097 7 foals foal NNS cord-022526-j9kg00qf 3097 8 often often RB cord-022526-j9kg00qf 3097 9 warrant warrant VBP cord-022526-j9kg00qf 3097 10 a a DT cord-022526-j9kg00qf 3097 11 guarded guard VBN cord-022526-j9kg00qf 3097 12 prognosis prognosis NN cord-022526-j9kg00qf 3097 13 . . . cord-022526-j9kg00qf 3098 1 Pyloric pyloric JJ cord-022526-j9kg00qf 3098 2 stenosis stenosis NN cord-022526-j9kg00qf 3098 3 is be VBZ cord-022526-j9kg00qf 3098 4 a a DT cord-022526-j9kg00qf 3098 5 structural structural JJ cord-022526-j9kg00qf 3098 6 resistance resistance NN cord-022526-j9kg00qf 3098 7 to to IN cord-022526-j9kg00qf 3098 8 gastric gastric JJ cord-022526-j9kg00qf 3098 9 outflow outflow NN cord-022526-j9kg00qf 3098 10 . . . cord-022526-j9kg00qf 3099 1 Congenital congenital JJ cord-022526-j9kg00qf 3099 2 pyloric pyloric JJ cord-022526-j9kg00qf 3099 3 stenosis stenosis NN cord-022526-j9kg00qf 3099 4 has have VBZ cord-022526-j9kg00qf 3099 5 been be VBN cord-022526-j9kg00qf 3099 6 reported report VBN cord-022526-j9kg00qf 3099 7 in in IN cord-022526-j9kg00qf 3099 8 foals foal NNS cord-022526-j9kg00qf 3099 9 and and CC cord-022526-j9kg00qf 3099 10 one one CD cord-022526-j9kg00qf 3099 11 yearling yearling NN cord-022526-j9kg00qf 3099 12 and and CC cord-022526-j9kg00qf 3099 13 results result NNS cord-022526-j9kg00qf 3099 14 from from IN cord-022526-j9kg00qf 3099 15 hypertrophy hypertrophy NN cord-022526-j9kg00qf 3099 16 of of IN cord-022526-j9kg00qf 3099 17 the the DT cord-022526-j9kg00qf 3099 18 pyloric pyloric JJ cord-022526-j9kg00qf 3099 19 musculature musculature NN cord-022526-j9kg00qf 3099 20 . . . cord-022526-j9kg00qf 3100 1 [ [ -LRB- cord-022526-j9kg00qf 3100 2 83 83 CD cord-022526-j9kg00qf 3100 3 ] ] -RRB- cord-022526-j9kg00qf 3100 4 [ [ -LRB- cord-022526-j9kg00qf 3100 5 84 84 CD cord-022526-j9kg00qf 3100 6 ] ] -RRB- cord-022526-j9kg00qf 3101 1 [ [ -LRB- cord-022526-j9kg00qf 3101 2 85 85 CD cord-022526-j9kg00qf 3101 3 ] ] -RRB- cord-022526-j9kg00qf 3101 4 Acquired acquire VBN cord-022526-j9kg00qf 3101 5 pyloric pyloric JJ cord-022526-j9kg00qf 3101 6 stenosis stenosis NN cord-022526-j9kg00qf 3101 7 can can MD cord-022526-j9kg00qf 3101 8 result result VB cord-022526-j9kg00qf 3101 9 from from IN cord-022526-j9kg00qf 3101 10 neoplasia neoplasia NN cord-022526-j9kg00qf 3101 11 or or CC cord-022526-j9kg00qf 3101 12 duodenal duodenal JJ cord-022526-j9kg00qf 3101 13 ulceration ulceration NN cord-022526-j9kg00qf 3101 14 . . . cord-022526-j9kg00qf 3102 1 [ [ -LRB- cord-022526-j9kg00qf 3102 2 86 86 CD cord-022526-j9kg00qf 3102 3 ] ] -RRB- cord-022526-j9kg00qf 3102 4 [ [ -LRB- cord-022526-j9kg00qf 3102 5 87 87 CD cord-022526-j9kg00qf 3102 6 ] ] -RRB- cord-022526-j9kg00qf 3102 7 [ [ -LRB- cord-022526-j9kg00qf 3102 8 88 88 CD cord-022526-j9kg00qf 3102 9 ] ] -RRB- cord-022526-j9kg00qf 3103 1 [ [ -LRB- cord-022526-j9kg00qf 3103 2 89 89 CD cord-022526-j9kg00qf 3103 3 ] ] -RRB- cord-022526-j9kg00qf 3104 1 Clinical clinical JJ cord-022526-j9kg00qf 3104 2 signs sign NNS cord-022526-j9kg00qf 3104 3 depend depend VBP cord-022526-j9kg00qf 3104 4 on on IN cord-022526-j9kg00qf 3104 5 the the DT cord-022526-j9kg00qf 3104 6 degree degree NN cord-022526-j9kg00qf 3104 7 of of IN cord-022526-j9kg00qf 3104 8 obstruction obstruction NN cord-022526-j9kg00qf 3104 9 and and CC cord-022526-j9kg00qf 3104 10 include include VBP cord-022526-j9kg00qf 3104 11 abdominal abdominal JJ cord-022526-j9kg00qf 3104 12 pain pain NN cord-022526-j9kg00qf 3104 13 , , , cord-022526-j9kg00qf 3104 14 salivation salivation NN cord-022526-j9kg00qf 3104 15 , , , cord-022526-j9kg00qf 3104 16 and and CC cord-022526-j9kg00qf 3104 17 teeth tooth NNS cord-022526-j9kg00qf 3104 18 grinding grind VBG cord-022526-j9kg00qf 3104 19 . . . cord-022526-j9kg00qf 3105 1 Complete complete JJ cord-022526-j9kg00qf 3105 2 or or CC cord-022526-j9kg00qf 3105 3 near near IN cord-022526-j9kg00qf 3105 4 complete complete JJ cord-022526-j9kg00qf 3105 5 obstruction obstruction NN cord-022526-j9kg00qf 3105 6 can can MD cord-022526-j9kg00qf 3105 7 result result VB cord-022526-j9kg00qf 3105 8 in in IN cord-022526-j9kg00qf 3105 9 gastric gastric JJ cord-022526-j9kg00qf 3105 10 reflux reflux NN cord-022526-j9kg00qf 3105 11 and and CC cord-022526-j9kg00qf 3105 12 reflux reflux NN cord-022526-j9kg00qf 3105 13 esophagitis esophagitis NN cord-022526-j9kg00qf 3105 14 . . . cord-022526-j9kg00qf 3106 1 In in IN cord-022526-j9kg00qf 3106 2 foals foal NNS cord-022526-j9kg00qf 3106 3 with with IN cord-022526-j9kg00qf 3106 4 congenital congenital JJ cord-022526-j9kg00qf 3106 5 pyloric pyloric JJ cord-022526-j9kg00qf 3106 6 hypertrophy hypertrophy NN cord-022526-j9kg00qf 3106 7 , , , cord-022526-j9kg00qf 3106 8 clinical clinical JJ cord-022526-j9kg00qf 3106 9 signs sign NNS cord-022526-j9kg00qf 3106 10 may may MD cord-022526-j9kg00qf 3106 11 begin begin VB cord-022526-j9kg00qf 3106 12 with with IN cord-022526-j9kg00qf 3106 13 the the DT cord-022526-j9kg00qf 3106 14 consumption consumption NN cord-022526-j9kg00qf 3106 15 of of IN cord-022526-j9kg00qf 3106 16 solid solid JJ cord-022526-j9kg00qf 3106 17 feed feed NN cord-022526-j9kg00qf 3106 18 . . . cord-022526-j9kg00qf 3107 1 In in IN cord-022526-j9kg00qf 3107 2 foals foal NNS cord-022526-j9kg00qf 3107 3 one one PRP cord-022526-j9kg00qf 3107 4 can can MD cord-022526-j9kg00qf 3107 5 make make VB cord-022526-j9kg00qf 3107 6 a a DT cord-022526-j9kg00qf 3107 7 presumptive presumptive JJ cord-022526-j9kg00qf 3107 8 diagnosis diagnosis NN cord-022526-j9kg00qf 3107 9 via via IN cord-022526-j9kg00qf 3107 10 gastric gastric JJ cord-022526-j9kg00qf 3107 11 endoscopy endoscopy NN cord-022526-j9kg00qf 3107 12 and and CC cord-022526-j9kg00qf 3107 13 radiography radiography NN cord-022526-j9kg00qf 3107 14 ( ( -LRB- cord-022526-j9kg00qf 3107 15 plain plain JJ cord-022526-j9kg00qf 3107 16 and and CC cord-022526-j9kg00qf 3107 17 contrast contrast JJ cord-022526-j9kg00qf 3107 18 studies study NNS cord-022526-j9kg00qf 3107 19 ) ) -RRB- cord-022526-j9kg00qf 3107 20 . . . cord-022526-j9kg00qf 3108 1 Depending depend VBG cord-022526-j9kg00qf 3108 2 on on IN cord-022526-j9kg00qf 3108 3 the the DT cord-022526-j9kg00qf 3108 4 cause cause NN cord-022526-j9kg00qf 3108 5 and and CC cord-022526-j9kg00qf 3108 6 severity severity NN cord-022526-j9kg00qf 3108 7 of of IN cord-022526-j9kg00qf 3108 8 disease disease NN cord-022526-j9kg00qf 3108 9 , , , cord-022526-j9kg00qf 3108 10 gastric gastric JJ cord-022526-j9kg00qf 3108 11 endoscopy endoscopy NN cord-022526-j9kg00qf 3108 12 may may MD cord-022526-j9kg00qf 3108 13 provide provide VB cord-022526-j9kg00qf 3108 14 a a DT cord-022526-j9kg00qf 3108 15 presumptive presumptive JJ cord-022526-j9kg00qf 3108 16 diagnosis diagnosis NN cord-022526-j9kg00qf 3108 17 in in IN cord-022526-j9kg00qf 3108 18 the the DT cord-022526-j9kg00qf 3108 19 adult adult NN cord-022526-j9kg00qf 3108 20 horse horse NN cord-022526-j9kg00qf 3108 21 . . . cord-022526-j9kg00qf 3109 1 Measurement measurement NN cord-022526-j9kg00qf 3109 2 of of IN cord-022526-j9kg00qf 3109 3 gastric gastric JJ cord-022526-j9kg00qf 3109 4 emptying emptying NN cord-022526-j9kg00qf 3109 5 can can MD cord-022526-j9kg00qf 3109 6 aid aid VB cord-022526-j9kg00qf 3109 7 the the DT cord-022526-j9kg00qf 3109 8 diagnosis diagnosis NN cord-022526-j9kg00qf 3109 9 . . . cord-022526-j9kg00qf 3110 1 Several several JJ cord-022526-j9kg00qf 3110 2 methods method NNS cord-022526-j9kg00qf 3110 3 of of IN cord-022526-j9kg00qf 3110 4 measurement measurement NN cord-022526-j9kg00qf 3110 5 are be VBP cord-022526-j9kg00qf 3110 6 currently currently RB cord-022526-j9kg00qf 3110 7 available available JJ cord-022526-j9kg00qf 3110 8 , , , cord-022526-j9kg00qf 3110 9 including include VBG cord-022526-j9kg00qf 3110 10 nuclear nuclear JJ cord-022526-j9kg00qf 3110 11 scintigraphy scintigraphy NN cord-022526-j9kg00qf 3110 12 , , , cord-022526-j9kg00qf 3110 13 acetaminophen acetaminophen NN cord-022526-j9kg00qf 3110 14 absorption absorption NN cord-022526-j9kg00qf 3110 15 , , , cord-022526-j9kg00qf 3110 16 and and CC cord-022526-j9kg00qf 3110 17 postconsumption postconsumption NN cord-022526-j9kg00qf 3110 18 [ [ -LRB- cord-022526-j9kg00qf 3110 19 13 13 CD cord-022526-j9kg00qf 3110 20 C C NNP cord-022526-j9kg00qf 3110 21 ] ] -RRB- cord-022526-j9kg00qf 3110 22 octanoic octanoic JJ cord-022526-j9kg00qf 3110 23 acid acid NN cord-022526-j9kg00qf 3110 24 blood blood NN cord-022526-j9kg00qf 3110 25 or or CC cord-022526-j9kg00qf 3110 26 breath breath NN cord-022526-j9kg00qf 3110 27 testing testing NN cord-022526-j9kg00qf 3110 28 . . . cord-022526-j9kg00qf 3111 1 81 81 CD cord-022526-j9kg00qf 3111 2 , , , cord-022526-j9kg00qf 3111 3 90 90 CD cord-022526-j9kg00qf 3111 4 , , , cord-022526-j9kg00qf 3111 5 91 91 CD cord-022526-j9kg00qf 3111 6 Exploratory exploratory JJ cord-022526-j9kg00qf 3111 7 laparotomy laparotomy NN cord-022526-j9kg00qf 3111 8 shows show VBZ cord-022526-j9kg00qf 3111 9 a a DT cord-022526-j9kg00qf 3111 10 distended distended JJ cord-022526-j9kg00qf 3111 11 stomach stomach NN cord-022526-j9kg00qf 3111 12 and and CC cord-022526-j9kg00qf 3111 13 thickened thickened JJ cord-022526-j9kg00qf 3111 14 pylorus pylorus NN cord-022526-j9kg00qf 3111 15 accompanied accompany VBN cord-022526-j9kg00qf 3111 16 by by IN cord-022526-j9kg00qf 3111 17 a a DT cord-022526-j9kg00qf 3111 18 relatively relatively RB cord-022526-j9kg00qf 3111 19 empty empty JJ cord-022526-j9kg00qf 3111 20 intestinal intestinal JJ cord-022526-j9kg00qf 3111 21 tract tract NN cord-022526-j9kg00qf 3111 22 . . . cord-022526-j9kg00qf 3112 1 If if IN cord-022526-j9kg00qf 3112 2 complete complete JJ cord-022526-j9kg00qf 3112 3 obstruction obstruction NN cord-022526-j9kg00qf 3112 4 is be VBZ cord-022526-j9kg00qf 3112 5 not not RB cord-022526-j9kg00qf 3112 6 present present JJ cord-022526-j9kg00qf 3112 7 , , , cord-022526-j9kg00qf 3112 8 medical medical JJ cord-022526-j9kg00qf 3112 9 therapy therapy NN cord-022526-j9kg00qf 3112 10 with with IN cord-022526-j9kg00qf 3112 11 a a DT cord-022526-j9kg00qf 3112 12 prokinetic prokinetic JJ cord-022526-j9kg00qf 3112 13 such such JJ cord-022526-j9kg00qf 3112 14 as as IN cord-022526-j9kg00qf 3112 15 bethanechol bethanechol NNP cord-022526-j9kg00qf 3112 16 can can MD cord-022526-j9kg00qf 3112 17 increase increase VB cord-022526-j9kg00qf 3112 18 the the DT cord-022526-j9kg00qf 3112 19 rate rate NN cord-022526-j9kg00qf 3112 20 of of IN cord-022526-j9kg00qf 3112 21 gastric gastric JJ cord-022526-j9kg00qf 3112 22 emptying emptying NN cord-022526-j9kg00qf 3112 23 . . . cord-022526-j9kg00qf 3113 1 81 81 CD cord-022526-j9kg00qf 3113 2 Phenylbutazone Phenylbutazone NNP cord-022526-j9kg00qf 3113 3 and and CC cord-022526-j9kg00qf 3113 4 cisapride cisapride NNP cord-022526-j9kg00qf 3113 5 also also RB cord-022526-j9kg00qf 3113 6 have have VBP cord-022526-j9kg00qf 3113 7 been be VBN cord-022526-j9kg00qf 3113 8 shown show VBN cord-022526-j9kg00qf 3113 9 to to TO cord-022526-j9kg00qf 3113 10 attenuate attenuate VB cord-022526-j9kg00qf 3113 11 the the DT cord-022526-j9kg00qf 3113 12 delay delay NN cord-022526-j9kg00qf 3113 13 in in IN cord-022526-j9kg00qf 3113 14 gastric gastric JJ cord-022526-j9kg00qf 3113 15 emptying emptying NN cord-022526-j9kg00qf 3113 16 caused cause VBN cord-022526-j9kg00qf 3113 17 by by IN cord-022526-j9kg00qf 3113 18 endotoxin endotoxin NN cord-022526-j9kg00qf 3113 19 administration administration NN cord-022526-j9kg00qf 3113 20 . . . cord-022526-j9kg00qf 3114 1 90 90 CD cord-022526-j9kg00qf 3114 2 , , , cord-022526-j9kg00qf 3114 3 92 92 CD cord-022526-j9kg00qf 3114 4 Surgical surgical JJ cord-022526-j9kg00qf 3114 5 repair repair NN cord-022526-j9kg00qf 3114 6 is be VBZ cord-022526-j9kg00qf 3114 7 necessary necessary JJ cord-022526-j9kg00qf 3114 8 for for IN cord-022526-j9kg00qf 3114 9 definitive definitive JJ cord-022526-j9kg00qf 3114 10 treatment treatment NN cord-022526-j9kg00qf 3114 11 of of IN cord-022526-j9kg00qf 3114 12 complete complete JJ cord-022526-j9kg00qf 3114 13 or or CC cord-022526-j9kg00qf 3114 14 near near RB cord-022526-j9kg00qf 3114 15 - - HYPH cord-022526-j9kg00qf 3114 16 complete complete JJ cord-022526-j9kg00qf 3114 17 obstruction obstruction NN cord-022526-j9kg00qf 3114 18 and and CC cord-022526-j9kg00qf 3114 19 consists consist VBZ cord-022526-j9kg00qf 3114 20 of of IN cord-022526-j9kg00qf 3114 21 gastroenterostomy gastroenterostomy NN cord-022526-j9kg00qf 3114 22 or or CC cord-022526-j9kg00qf 3114 23 pyloroplasty pyloroplasty NNP cord-022526-j9kg00qf 3114 24 . . . cord-022526-j9kg00qf 3115 1 57 57 CD cord-022526-j9kg00qf 3115 2 , , , cord-022526-j9kg00qf 3115 3 82 82 CD cord-022526-j9kg00qf 3115 4 _SP cord-022526-j9kg00qf 3115 5 Gastric gastric JJ cord-022526-j9kg00qf 3115 6 dilation dilation NN cord-022526-j9kg00qf 3115 7 can can MD cord-022526-j9kg00qf 3115 8 be be VB cord-022526-j9kg00qf 3115 9 classified classify VBN cord-022526-j9kg00qf 3115 10 as as IN cord-022526-j9kg00qf 3115 11 primary primary JJ cord-022526-j9kg00qf 3115 12 , , , cord-022526-j9kg00qf 3115 13 secondary secondary JJ cord-022526-j9kg00qf 3115 14 , , , cord-022526-j9kg00qf 3115 15 or or CC cord-022526-j9kg00qf 3115 16 idiopathic idiopathic JJ cord-022526-j9kg00qf 3115 17 . . . cord-022526-j9kg00qf 3116 1 Causes cause NNS cord-022526-j9kg00qf 3116 2 of of IN cord-022526-j9kg00qf 3116 3 primary primary JJ cord-022526-j9kg00qf 3116 4 gastric gastric JJ cord-022526-j9kg00qf 3116 5 dilation dilation NN cord-022526-j9kg00qf 3116 6 include include VBP cord-022526-j9kg00qf 3116 7 gastric gastric JJ cord-022526-j9kg00qf 3116 8 impaction impaction NN cord-022526-j9kg00qf 3116 9 , , , cord-022526-j9kg00qf 3116 10 grain grain NN cord-022526-j9kg00qf 3116 11 engorgement engorgement NN cord-022526-j9kg00qf 3116 12 , , , cord-022526-j9kg00qf 3116 13 excessive excessive JJ cord-022526-j9kg00qf 3116 14 water water NN cord-022526-j9kg00qf 3116 15 intake intake NN cord-022526-j9kg00qf 3116 16 after after IN cord-022526-j9kg00qf 3116 17 exercise exercise NN cord-022526-j9kg00qf 3116 18 , , , cord-022526-j9kg00qf 3116 19 aerophagia aerophagia NNP cord-022526-j9kg00qf 3116 20 , , , cord-022526-j9kg00qf 3116 21 and and CC cord-022526-j9kg00qf 3116 22 parasitism parasitism NN cord-022526-j9kg00qf 3116 23 . . . cord-022526-j9kg00qf 3117 1 86 86 CD cord-022526-j9kg00qf 3117 2 , , , cord-022526-j9kg00qf 3117 3 93 93 CD cord-022526-j9kg00qf 3117 4 Secondary secondary JJ cord-022526-j9kg00qf 3117 5 gastric gastric JJ cord-022526-j9kg00qf 3117 6 dilation dilation NN cord-022526-j9kg00qf 3117 7 occurs occur VBZ cord-022526-j9kg00qf 3117 8 more more RBR cord-022526-j9kg00qf 3117 9 commonly commonly RB cord-022526-j9kg00qf 3117 10 and and CC cord-022526-j9kg00qf 3117 11 can can MD cord-022526-j9kg00qf 3117 12 result result VB cord-022526-j9kg00qf 3117 13 from from IN cord-022526-j9kg00qf 3117 14 primary primary JJ cord-022526-j9kg00qf 3117 15 intestinal intestinal JJ cord-022526-j9kg00qf 3117 16 ileus ileus NN cord-022526-j9kg00qf 3117 17 or or CC cord-022526-j9kg00qf 3117 18 small small JJ cord-022526-j9kg00qf 3117 19 or or CC cord-022526-j9kg00qf 3117 20 large large JJ cord-022526-j9kg00qf 3117 21 intestinal intestinal JJ cord-022526-j9kg00qf 3117 22 obstruction obstruction NN cord-022526-j9kg00qf 3117 23 . . . cord-022526-j9kg00qf 3118 1 Time time NN cord-022526-j9kg00qf 3118 2 to to IN cord-022526-j9kg00qf 3118 3 development development NN cord-022526-j9kg00qf 3118 4 of of IN cord-022526-j9kg00qf 3118 5 gastric gastric JJ cord-022526-j9kg00qf 3118 6 reflux reflux NN cord-022526-j9kg00qf 3118 7 is be VBZ cord-022526-j9kg00qf 3118 8 proportional proportional JJ cord-022526-j9kg00qf 3118 9 to to IN cord-022526-j9kg00qf 3118 10 the the DT cord-022526-j9kg00qf 3118 11 distance distance NN cord-022526-j9kg00qf 3118 12 to to IN cord-022526-j9kg00qf 3118 13 the the DT cord-022526-j9kg00qf 3118 14 intestinal intestinal JJ cord-022526-j9kg00qf 3118 15 segment segment NN cord-022526-j9kg00qf 3118 16 involved involve VBN cord-022526-j9kg00qf 3118 17 , , , cord-022526-j9kg00qf 3118 18 with with IN cord-022526-j9kg00qf 3118 19 duodenal duodenal JJ cord-022526-j9kg00qf 3118 20 obstruction obstruction NN cord-022526-j9kg00qf 3118 21 resulting result VBG cord-022526-j9kg00qf 3118 22 in in IN cord-022526-j9kg00qf 3118 23 reflux reflux NN cord-022526-j9kg00qf 3118 24 within within IN cord-022526-j9kg00qf 3118 25 4 4 CD cord-022526-j9kg00qf 3118 26 hours hour NNS cord-022526-j9kg00qf 3118 27 . . . cord-022526-j9kg00qf 3119 1 94 94 CD cord-022526-j9kg00qf 3119 2 Clinical clinical JJ cord-022526-j9kg00qf 3119 3 signs sign NNS cord-022526-j9kg00qf 3119 4 of of IN cord-022526-j9kg00qf 3119 5 gastric gastric JJ cord-022526-j9kg00qf 3119 6 dilation dilation NN cord-022526-j9kg00qf 3119 7 include include VBP cord-022526-j9kg00qf 3119 8 those those DT cord-022526-j9kg00qf 3119 9 associated associate VBN cord-022526-j9kg00qf 3119 10 with with IN cord-022526-j9kg00qf 3119 11 acute acute JJ cord-022526-j9kg00qf 3119 12 colic colic NN cord-022526-j9kg00qf 3119 13 and and CC cord-022526-j9kg00qf 3119 14 in in IN cord-022526-j9kg00qf 3119 15 severe severe JJ cord-022526-j9kg00qf 3119 16 cases case NNS cord-022526-j9kg00qf 3119 17 , , , cord-022526-j9kg00qf 3119 18 ingesta ingesta NNP cord-022526-j9kg00qf 3119 19 appearing appear VBG cord-022526-j9kg00qf 3119 20 at at IN cord-022526-j9kg00qf 3119 21 the the DT cord-022526-j9kg00qf 3119 22 nares naris NNS cord-022526-j9kg00qf 3119 23 . . . cord-022526-j9kg00qf 3120 1 Associated associated JJ cord-022526-j9kg00qf 3120 2 laboratory laboratory NN cord-022526-j9kg00qf 3120 3 abnormalities abnormality NNS cord-022526-j9kg00qf 3120 4 include include VBP cord-022526-j9kg00qf 3120 5 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 3120 6 , , , cord-022526-j9kg00qf 3120 7 hypokalemia hypokalemia NN cord-022526-j9kg00qf 3120 8 , , , cord-022526-j9kg00qf 3120 9 and and CC cord-022526-j9kg00qf 3120 10 hypochloremia hypochloremia NN cord-022526-j9kg00qf 3120 11 . . . cord-022526-j9kg00qf 3121 1 86 86 CD cord-022526-j9kg00qf 3122 1 The the DT cord-022526-j9kg00qf 3122 2 most most RBS cord-022526-j9kg00qf 3122 3 common common JJ cord-022526-j9kg00qf 3122 4 reported report VBN cord-022526-j9kg00qf 3122 5 cause cause NN cord-022526-j9kg00qf 3122 6 of of IN cord-022526-j9kg00qf 3122 7 gastric gastric JJ cord-022526-j9kg00qf 3122 8 rupture rupture NN cord-022526-j9kg00qf 3122 9 in in IN cord-022526-j9kg00qf 3122 10 horses horse NNS cord-022526-j9kg00qf 3122 11 varies vary VBZ cord-022526-j9kg00qf 3122 12 between between IN cord-022526-j9kg00qf 3122 13 reports report NNS cord-022526-j9kg00qf 3122 14 . . . cord-022526-j9kg00qf 3123 1 In in IN cord-022526-j9kg00qf 3123 2 a a DT cord-022526-j9kg00qf 3123 3 retrospective retrospective JJ cord-022526-j9kg00qf 3123 4 study study NN cord-022526-j9kg00qf 3123 5 of of IN cord-022526-j9kg00qf 3123 6 54 54 CD cord-022526-j9kg00qf 3123 7 horses horse NNS cord-022526-j9kg00qf 3123 8 , , , cord-022526-j9kg00qf 3123 9 gastric gastric JJ cord-022526-j9kg00qf 3123 10 rupture rupture NN cord-022526-j9kg00qf 3123 11 occurred occur VBD cord-022526-j9kg00qf 3123 12 most most RBS cord-022526-j9kg00qf 3123 13 commonly commonly RB cord-022526-j9kg00qf 3123 14 as as IN cord-022526-j9kg00qf 3123 15 a a DT cord-022526-j9kg00qf 3123 16 secondary secondary JJ cord-022526-j9kg00qf 3123 17 phenomenon phenomenon NN cord-022526-j9kg00qf 3123 18 ( ( -LRB- cord-022526-j9kg00qf 3123 19 65 65 CD cord-022526-j9kg00qf 3123 20 % % NN cord-022526-j9kg00qf 3123 21 ) ) -RRB- cord-022526-j9kg00qf 3123 22 , , , cord-022526-j9kg00qf 3123 23 usually usually RB cord-022526-j9kg00qf 3123 24 because because IN cord-022526-j9kg00qf 3123 25 of of IN cord-022526-j9kg00qf 3123 26 small small JJ cord-022526-j9kg00qf 3123 27 intestinal intestinal JJ cord-022526-j9kg00qf 3123 28 obstruction obstruction NN cord-022526-j9kg00qf 3123 29 , , , cord-022526-j9kg00qf 3123 30 with with IN cord-022526-j9kg00qf 3123 31 primary primary JJ cord-022526-j9kg00qf 3123 32 gastric gastric JJ cord-022526-j9kg00qf 3123 33 dilation dilation NN cord-022526-j9kg00qf 3123 34 and and CC cord-022526-j9kg00qf 3123 35 idiopathic idiopathic JJ cord-022526-j9kg00qf 3123 36 rupture rupture NN cord-022526-j9kg00qf 3123 37 occurring occur VBG cord-022526-j9kg00qf 3123 38 almost almost RB cord-022526-j9kg00qf 3123 39 equally equally RB cord-022526-j9kg00qf 3123 40 ( ( -LRB- cord-022526-j9kg00qf 3123 41 15 15 CD cord-022526-j9kg00qf 3123 42 % % NN cord-022526-j9kg00qf 3123 43 and and CC cord-022526-j9kg00qf 3123 44 17 17 CD cord-022526-j9kg00qf 3123 45 % % NN cord-022526-j9kg00qf 3123 46 , , , cord-022526-j9kg00qf 3123 47 respectively respectively RB cord-022526-j9kg00qf 3123 48 ) ) -RRB- cord-022526-j9kg00qf 3123 49 . . . cord-022526-j9kg00qf 3124 1 93 93 CD cord-022526-j9kg00qf 3125 1 In in IN cord-022526-j9kg00qf 3125 2 another another DT cord-022526-j9kg00qf 3125 3 retrospective retrospective JJ cord-022526-j9kg00qf 3125 4 study study NN cord-022526-j9kg00qf 3125 5 of of IN cord-022526-j9kg00qf 3125 6 50 50 CD cord-022526-j9kg00qf 3125 7 horses horse NNS cord-022526-j9kg00qf 3125 8 in in IN cord-022526-j9kg00qf 3125 9 combination combination NN cord-022526-j9kg00qf 3125 10 with with IN cord-022526-j9kg00qf 3125 11 a a DT cord-022526-j9kg00qf 3125 12 search search NN cord-022526-j9kg00qf 3125 13 of of IN cord-022526-j9kg00qf 3125 14 the the DT cord-022526-j9kg00qf 3125 15 Veterinary Veterinary NNP cord-022526-j9kg00qf 3125 16 Medical Medical NNP cord-022526-j9kg00qf 3125 17 Database Database NNP cord-022526-j9kg00qf 3125 18 ( ( -LRB- cord-022526-j9kg00qf 3125 19 VMDB VMDB NNP cord-022526-j9kg00qf 3125 20 ) ) -RRB- cord-022526-j9kg00qf 3125 21 , , , cord-022526-j9kg00qf 3125 22 60 60 CD cord-022526-j9kg00qf 3125 23 % % NN cord-022526-j9kg00qf 3125 24 of of IN cord-022526-j9kg00qf 3125 25 the the DT cord-022526-j9kg00qf 3125 26 gastric gastric JJ cord-022526-j9kg00qf 3125 27 rupture rupture NN cord-022526-j9kg00qf 3125 28 cases case NNS cord-022526-j9kg00qf 3125 29 were be VBD cord-022526-j9kg00qf 3125 30 classified classify VBN cord-022526-j9kg00qf 3125 31 as as IN cord-022526-j9kg00qf 3125 32 idiopathic idiopathic JJ cord-022526-j9kg00qf 3125 33 . . . cord-022526-j9kg00qf 3126 1 95 95 CD cord-022526-j9kg00qf 3126 2 Risk risk NN cord-022526-j9kg00qf 3126 3 factors factor NNS cord-022526-j9kg00qf 3126 4 for for IN cord-022526-j9kg00qf 3126 5 gastric gastric JJ cord-022526-j9kg00qf 3126 6 rupture rupture NN cord-022526-j9kg00qf 3126 7 include include VBP cord-022526-j9kg00qf 3126 8 feeding feed VBG cord-022526-j9kg00qf 3126 9 grass grass NN cord-022526-j9kg00qf 3126 10 hay hay NN cord-022526-j9kg00qf 3126 11 , , , cord-022526-j9kg00qf 3126 12 not not RB cord-022526-j9kg00qf 3126 13 feeding feed VBG cord-022526-j9kg00qf 3126 14 grain grain NN cord-022526-j9kg00qf 3126 15 , , , cord-022526-j9kg00qf 3126 16 gelding gelding NN cord-022526-j9kg00qf 3126 17 , , , cord-022526-j9kg00qf 3126 18 and and CC cord-022526-j9kg00qf 3126 19 a a DT cord-022526-j9kg00qf 3126 20 nonautomatic nonautomatic JJ cord-022526-j9kg00qf 3126 21 water water NN cord-022526-j9kg00qf 3126 22 source source NN cord-022526-j9kg00qf 3126 23 . . . cord-022526-j9kg00qf 3127 1 93 93 CD cord-022526-j9kg00qf 3127 2 , , , cord-022526-j9kg00qf 3127 3 95 95 CD cord-022526-j9kg00qf 3128 1 Nasogastric nasogastric JJ cord-022526-j9kg00qf 3128 2 intubation intubation NN cord-022526-j9kg00qf 3128 3 does do VBZ cord-022526-j9kg00qf 3128 4 not not RB cord-022526-j9kg00qf 3128 5 preclude preclude VB cord-022526-j9kg00qf 3128 6 the the DT cord-022526-j9kg00qf 3128 7 possibility possibility NN cord-022526-j9kg00qf 3128 8 of of IN cord-022526-j9kg00qf 3128 9 gastric gastric JJ cord-022526-j9kg00qf 3128 10 rupture rupture NN cord-022526-j9kg00qf 3128 11 , , , cord-022526-j9kg00qf 3128 12 and and CC cord-022526-j9kg00qf 3128 13 the the DT cord-022526-j9kg00qf 3128 14 amount amount NN cord-022526-j9kg00qf 3128 15 of of IN cord-022526-j9kg00qf 3128 16 reflux reflux NN cord-022526-j9kg00qf 3128 17 obtained obtain VBN cord-022526-j9kg00qf 3128 18 before before IN cord-022526-j9kg00qf 3128 19 rupture rupture NN cord-022526-j9kg00qf 3128 20 varies vary VBZ cord-022526-j9kg00qf 3128 21 greatly greatly RB cord-022526-j9kg00qf 3128 22 . . . cord-022526-j9kg00qf 3129 1 93 93 CD cord-022526-j9kg00qf 3130 1 Because because IN cord-022526-j9kg00qf 3130 2 these these DT cord-022526-j9kg00qf 3130 3 reports report NNS cord-022526-j9kg00qf 3130 4 were be VBD cord-022526-j9kg00qf 3130 5 retrospective retrospective JJ cord-022526-j9kg00qf 3130 6 , , , cord-022526-j9kg00qf 3130 7 one one PRP cord-022526-j9kg00qf 3130 8 can can MD cord-022526-j9kg00qf 3130 9 not not RB cord-022526-j9kg00qf 3130 10 rule rule VB cord-022526-j9kg00qf 3130 11 out out RP cord-022526-j9kg00qf 3130 12 confounding confounding JJ cord-022526-j9kg00qf 3130 13 factors factor NNS cord-022526-j9kg00qf 3130 14 with with IN cord-022526-j9kg00qf 3130 15 certainty certainty NN cord-022526-j9kg00qf 3130 16 . . . cord-022526-j9kg00qf 3131 1 Regardless regardless RB cord-022526-j9kg00qf 3131 2 of of IN cord-022526-j9kg00qf 3131 3 the the DT cord-022526-j9kg00qf 3131 4 initiating initiating NN cord-022526-j9kg00qf 3131 5 cause cause NN cord-022526-j9kg00qf 3131 6 , , , cord-022526-j9kg00qf 3131 7 gastric gastric JJ cord-022526-j9kg00qf 3131 8 rupture rupture NN cord-022526-j9kg00qf 3131 9 usually usually RB cord-022526-j9kg00qf 3131 10 occurs occur VBZ cord-022526-j9kg00qf 3131 11 along along IN cord-022526-j9kg00qf 3131 12 the the DT cord-022526-j9kg00qf 3131 13 greater great JJR cord-022526-j9kg00qf 3131 14 curvature curvature NN cord-022526-j9kg00qf 3131 15 . . . cord-022526-j9kg00qf 3132 1 In in IN cord-022526-j9kg00qf 3132 2 horses horse NNS cord-022526-j9kg00qf 3132 3 with with IN cord-022526-j9kg00qf 3132 4 rupture rupture NN cord-022526-j9kg00qf 3132 5 caused cause VBN cord-022526-j9kg00qf 3132 6 by by IN cord-022526-j9kg00qf 3132 7 gastric gastric JJ cord-022526-j9kg00qf 3132 8 dilation dilation NN cord-022526-j9kg00qf 3132 9 , , , cord-022526-j9kg00qf 3132 10 tears tear NNS cord-022526-j9kg00qf 3132 11 in in IN cord-022526-j9kg00qf 3132 12 the the DT cord-022526-j9kg00qf 3132 13 seromuscular seromuscular NNP cord-022526-j9kg00qf 3132 14 layer layer NN cord-022526-j9kg00qf 3132 15 are be VBP cord-022526-j9kg00qf 3132 16 frequently frequently RB cord-022526-j9kg00qf 3132 17 larger large JJR cord-022526-j9kg00qf 3132 18 than than IN cord-022526-j9kg00qf 3132 19 the the DT cord-022526-j9kg00qf 3132 20 corresponding correspond VBG cord-022526-j9kg00qf 3132 21 tears tear NNS cord-022526-j9kg00qf 3132 22 in in IN cord-022526-j9kg00qf 3132 23 the the DT cord-022526-j9kg00qf 3132 24 mucosal mucosal NN cord-022526-j9kg00qf 3132 25 layer layer NN cord-022526-j9kg00qf 3132 26 , , , cord-022526-j9kg00qf 3132 27 indicating indicate VBG cord-022526-j9kg00qf 3132 28 that that IN cord-022526-j9kg00qf 3132 29 the the DT cord-022526-j9kg00qf 3132 30 seromuscularis seromuscularis NN cord-022526-j9kg00qf 3132 31 likely likely RB cord-022526-j9kg00qf 3132 32 weakens weaken VBZ cord-022526-j9kg00qf 3132 33 and and CC cord-022526-j9kg00qf 3132 34 tears tear NNS cord-022526-j9kg00qf 3132 35 before before IN cord-022526-j9kg00qf 3132 36 the the DT cord-022526-j9kg00qf 3132 37 mucosa mucosa NN cord-022526-j9kg00qf 3132 38 . . . cord-022526-j9kg00qf 3133 1 93 93 CD cord-022526-j9kg00qf 3133 2 , , , cord-022526-j9kg00qf 3133 3 95 95 CD cord-022526-j9kg00qf 3134 1 In in IN cord-022526-j9kg00qf 3134 2 contrast contrast NN cord-022526-j9kg00qf 3134 3 , , , cord-022526-j9kg00qf 3134 4 horses horse NNS cord-022526-j9kg00qf 3134 5 with with IN cord-022526-j9kg00qf 3134 6 gastric gastric JJ cord-022526-j9kg00qf 3134 7 rupture rupture NN cord-022526-j9kg00qf 3134 8 following follow VBG cord-022526-j9kg00qf 3134 9 gastric gastric JJ cord-022526-j9kg00qf 3134 10 ulceration ulceration NN cord-022526-j9kg00qf 3134 11 usually usually RB cord-022526-j9kg00qf 3134 12 demonstrate demonstrate VBP cord-022526-j9kg00qf 3134 13 full full JJ cord-022526-j9kg00qf 3134 14 - - HYPH cord-022526-j9kg00qf 3134 15 thickness thickness NN cord-022526-j9kg00qf 3134 16 tears tear NNS cord-022526-j9kg00qf 3134 17 of of IN cord-022526-j9kg00qf 3134 18 equal equal JJ cord-022526-j9kg00qf 3134 19 size size NN cord-022526-j9kg00qf 3134 20 in in IN cord-022526-j9kg00qf 3134 21 all all DT cord-022526-j9kg00qf 3134 22 layers layer NNS cord-022526-j9kg00qf 3134 23 . . . cord-022526-j9kg00qf 3135 1 Gastric gastric JJ cord-022526-j9kg00qf 3135 2 rupture rupture NN cord-022526-j9kg00qf 3135 3 is be VBZ cord-022526-j9kg00qf 3135 4 usually usually RB cord-022526-j9kg00qf 3135 5 fatal fatal JJ cord-022526-j9kg00qf 3135 6 because because IN cord-022526-j9kg00qf 3135 7 of of IN cord-022526-j9kg00qf 3135 8 widespread widespread JJ cord-022526-j9kg00qf 3135 9 contamination contamination NN cord-022526-j9kg00qf 3135 10 of of IN cord-022526-j9kg00qf 3135 11 the the DT cord-022526-j9kg00qf 3135 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 3135 13 cavity cavity NN cord-022526-j9kg00qf 3135 14 , , , cord-022526-j9kg00qf 3135 15 septic septic JJ cord-022526-j9kg00qf 3135 16 peritonitis peritonitis NN cord-022526-j9kg00qf 3135 17 , , , cord-022526-j9kg00qf 3135 18 and and CC cord-022526-j9kg00qf 3135 19 septic septic JJ cord-022526-j9kg00qf 3135 20 shock shock NN cord-022526-j9kg00qf 3135 21 . . . cord-022526-j9kg00qf 3136 1 Initial initial JJ cord-022526-j9kg00qf 3136 2 clinical clinical JJ cord-022526-j9kg00qf 3136 3 signs sign NNS cord-022526-j9kg00qf 3136 4 vary vary VBP cord-022526-j9kg00qf 3136 5 with with IN cord-022526-j9kg00qf 3136 6 the the DT cord-022526-j9kg00qf 3136 7 primary primary JJ cord-022526-j9kg00qf 3136 8 disease disease NN cord-022526-j9kg00qf 3136 9 ; ; : cord-022526-j9kg00qf 3136 10 however however RB cord-022526-j9kg00qf 3136 11 , , , cord-022526-j9kg00qf 3136 12 when when WRB cord-022526-j9kg00qf 3136 13 rupture rupture NN cord-022526-j9kg00qf 3136 14 occurs occur VBZ cord-022526-j9kg00qf 3136 15 , , , cord-022526-j9kg00qf 3136 16 a a DT cord-022526-j9kg00qf 3136 17 previously previously RB cord-022526-j9kg00qf 3136 18 painful painful JJ cord-022526-j9kg00qf 3136 19 animal animal NN cord-022526-j9kg00qf 3136 20 can can MD cord-022526-j9kg00qf 3136 21 exhibit exhibit VB cord-022526-j9kg00qf 3136 22 signs sign NNS cord-022526-j9kg00qf 3136 23 of of IN cord-022526-j9kg00qf 3136 24 relief relief NN cord-022526-j9kg00qf 3136 25 . . . cord-022526-j9kg00qf 3137 1 Subsequent subsequent JJ cord-022526-j9kg00qf 3137 2 signs sign NNS cord-022526-j9kg00qf 3137 3 are be VBP cord-022526-j9kg00qf 3137 4 consistent consistent JJ cord-022526-j9kg00qf 3137 5 with with IN cord-022526-j9kg00qf 3137 6 peritonitis peritonitis NN cord-022526-j9kg00qf 3137 7 and and CC cord-022526-j9kg00qf 3137 8 shock shock NN cord-022526-j9kg00qf 3137 9 , , , cord-022526-j9kg00qf 3137 10 including include VBG cord-022526-j9kg00qf 3137 11 tachypnea tachypnea NNP cord-022526-j9kg00qf 3137 12 , , , cord-022526-j9kg00qf 3137 13 tachycardia tachycardia NN cord-022526-j9kg00qf 3137 14 , , , cord-022526-j9kg00qf 3137 15 sweating sweating NN cord-022526-j9kg00qf 3137 16 , , , cord-022526-j9kg00qf 3137 17 and and CC cord-022526-j9kg00qf 3137 18 muscle muscle NN cord-022526-j9kg00qf 3137 19 fasciculations fasciculation NNS cord-022526-j9kg00qf 3137 20 . . . cord-022526-j9kg00qf 3138 1 Surgical surgical JJ cord-022526-j9kg00qf 3138 2 repair repair NN cord-022526-j9kg00qf 3138 3 is be VBZ cord-022526-j9kg00qf 3138 4 thus thus RB cord-022526-j9kg00qf 3138 5 limited limit VBN cord-022526-j9kg00qf 3138 6 but but CC cord-022526-j9kg00qf 3138 7 has have VBZ cord-022526-j9kg00qf 3138 8 been be VBN cord-022526-j9kg00qf 3138 9 reported report VBN cord-022526-j9kg00qf 3138 10 for for IN cord-022526-j9kg00qf 3138 11 partial partial JJ cord-022526-j9kg00qf 3138 12 - - HYPH cord-022526-j9kg00qf 3138 13 thickness thickness NN cord-022526-j9kg00qf 3138 14 tears tear NNS cord-022526-j9kg00qf 3138 15 , , , cord-022526-j9kg00qf 3138 16 96 96 CD cord-022526-j9kg00qf 3138 17 and and CC cord-022526-j9kg00qf 3138 18 in in IN cord-022526-j9kg00qf 3138 19 one one CD cord-022526-j9kg00qf 3138 20 case case NN cord-022526-j9kg00qf 3138 21 of of IN cord-022526-j9kg00qf 3138 22 a a DT cord-022526-j9kg00qf 3138 23 combined combine VBN cord-022526-j9kg00qf 3138 24 tear tear NN cord-022526-j9kg00qf 3138 25 of of IN cord-022526-j9kg00qf 3138 26 the the DT cord-022526-j9kg00qf 3138 27 mucosa mucosa JJ cord-022526-j9kg00qf 3138 28 and and CC cord-022526-j9kg00qf 3138 29 muscularis muscularis JJ cord-022526-j9kg00qf 3138 30 with with IN cord-022526-j9kg00qf 3138 31 only only RB cord-022526-j9kg00qf 3138 32 a a DT cord-022526-j9kg00qf 3138 33 focal focal JJ cord-022526-j9kg00qf 3138 34 serosal serosal NN cord-022526-j9kg00qf 3138 35 tear tear NN cord-022526-j9kg00qf 3138 36 , , , cord-022526-j9kg00qf 3138 37 a a DT cord-022526-j9kg00qf 3138 38 full full JJ cord-022526-j9kg00qf 3138 39 - - HYPH cord-022526-j9kg00qf 3138 40 thickness thickness NN cord-022526-j9kg00qf 3138 41 repair repair NN cord-022526-j9kg00qf 3138 42 was be VBD cord-022526-j9kg00qf 3138 43 performed perform VBN cord-022526-j9kg00qf 3138 44 with with IN cord-022526-j9kg00qf 3138 45 a a DT cord-022526-j9kg00qf 3138 46 favorable favorable JJ cord-022526-j9kg00qf 3138 47 outcome outcome NN cord-022526-j9kg00qf 3138 48 . . . cord-022526-j9kg00qf 3139 1 97 97 CD cord-022526-j9kg00qf 3139 2 Gastric gastric JJ cord-022526-j9kg00qf 3139 3 impaction impaction NN cord-022526-j9kg00qf 3139 4 can can MD cord-022526-j9kg00qf 3139 5 result result VB cord-022526-j9kg00qf 3139 6 in in IN cord-022526-j9kg00qf 3139 7 acute acute JJ cord-022526-j9kg00qf 3139 8 or or CC cord-022526-j9kg00qf 3139 9 chronic chronic JJ cord-022526-j9kg00qf 3139 10 signs sign NNS cord-022526-j9kg00qf 3139 11 of of IN cord-022526-j9kg00qf 3139 12 colic colic NN cord-022526-j9kg00qf 3139 13 in in IN cord-022526-j9kg00qf 3139 14 the the DT cord-022526-j9kg00qf 3139 15 horse horse NN cord-022526-j9kg00qf 3139 16 . . . cord-022526-j9kg00qf 3140 1 Although although IN cord-022526-j9kg00qf 3140 2 a a DT cord-022526-j9kg00qf 3140 3 specific specific JJ cord-022526-j9kg00qf 3140 4 cause cause NN cord-022526-j9kg00qf 3140 5 is be VBZ cord-022526-j9kg00qf 3140 6 not not RB cord-022526-j9kg00qf 3140 7 always always RB cord-022526-j9kg00qf 3140 8 evident evident JJ cord-022526-j9kg00qf 3140 9 , , , cord-022526-j9kg00qf 3140 10 ingestion ingestion NN cord-022526-j9kg00qf 3140 11 of of IN cord-022526-j9kg00qf 3140 12 coarse coarse JJ cord-022526-j9kg00qf 3140 13 roughage roughage NN cord-022526-j9kg00qf 3140 14 ( ( -LRB- cord-022526-j9kg00qf 3140 15 straw straw NN cord-022526-j9kg00qf 3140 16 bedding bedding NN cord-022526-j9kg00qf 3140 17 , , , cord-022526-j9kg00qf 3140 18 poor poor JJ cord-022526-j9kg00qf 3140 19 - - HYPH cord-022526-j9kg00qf 3140 20 quality quality NN cord-022526-j9kg00qf 3140 21 forage forage NN cord-022526-j9kg00qf 3140 22 ) ) -RRB- cord-022526-j9kg00qf 3140 23 , , , cord-022526-j9kg00qf 3140 24 foreign foreign JJ cord-022526-j9kg00qf 3140 25 objects object NNS cord-022526-j9kg00qf 3140 26 ( ( -LRB- cord-022526-j9kg00qf 3140 27 rubber rubber NN cord-022526-j9kg00qf 3140 28 fencing fencing NN cord-022526-j9kg00qf 3140 29 material material NN cord-022526-j9kg00qf 3140 30 ) ) -RRB- cord-022526-j9kg00qf 3140 31 , , , cord-022526-j9kg00qf 3140 32 and and CC cord-022526-j9kg00qf 3140 33 feed feed VB cord-022526-j9kg00qf 3140 34 that that WDT cord-022526-j9kg00qf 3140 35 may may MD cord-022526-j9kg00qf 3140 36 swell swell VB cord-022526-j9kg00qf 3140 37 after after IN cord-022526-j9kg00qf 3140 38 ingestion ingestion NN cord-022526-j9kg00qf 3140 39 or or CC cord-022526-j9kg00qf 3140 40 improper improper JJ cord-022526-j9kg00qf 3140 41 mastication mastication NN cord-022526-j9kg00qf 3140 42 ( ( -LRB- cord-022526-j9kg00qf 3140 43 persimmon persimmon NN cord-022526-j9kg00qf 3140 44 seeds seed NNS cord-022526-j9kg00qf 3140 45 , , , cord-022526-j9kg00qf 3140 46 mesquite mesquite NN cord-022526-j9kg00qf 3140 47 beans bean NNS cord-022526-j9kg00qf 3140 48 , , , cord-022526-j9kg00qf 3140 49 wheat wheat NN cord-022526-j9kg00qf 3140 50 , , , cord-022526-j9kg00qf 3140 51 barley barley NN cord-022526-j9kg00qf 3140 52 , , , cord-022526-j9kg00qf 3140 53 sugar sugar NN cord-022526-j9kg00qf 3140 54 beet beet NN cord-022526-j9kg00qf 3140 55 pulp pulp NN cord-022526-j9kg00qf 3140 56 ) ) -RRB- cord-022526-j9kg00qf 3140 57 have have VBP cord-022526-j9kg00qf 3140 58 been be VBN cord-022526-j9kg00qf 3140 59 implicated implicate VBN cord-022526-j9kg00qf 3140 60 . . . cord-022526-j9kg00qf 3141 1 Possible possible JJ cord-022526-j9kg00qf 3141 2 predisposing predisposing JJ cord-022526-j9kg00qf 3141 3 factors factor NNS cord-022526-j9kg00qf 3141 4 include include VBP cord-022526-j9kg00qf 3141 5 poor poor JJ cord-022526-j9kg00qf 3141 6 dentition dentition NN cord-022526-j9kg00qf 3141 7 , , , cord-022526-j9kg00qf 3141 8 poor poor JJ cord-022526-j9kg00qf 3141 9 mastication mastication NN cord-022526-j9kg00qf 3141 10 and and CC cord-022526-j9kg00qf 3141 11 rapid rapid JJ cord-022526-j9kg00qf 3141 12 consumption consumption NN cord-022526-j9kg00qf 3141 13 of of IN cord-022526-j9kg00qf 3141 14 feedstuffs feedstuffs NN cord-022526-j9kg00qf 3141 15 , , , cord-022526-j9kg00qf 3141 16 and and CC cord-022526-j9kg00qf 3141 17 inadequate inadequate JJ cord-022526-j9kg00qf 3141 18 water water NN cord-022526-j9kg00qf 3141 19 consumption consumption NN cord-022526-j9kg00qf 3141 20 . . . cord-022526-j9kg00qf 3142 1 Clinical clinical JJ cord-022526-j9kg00qf 3142 2 signs sign NNS cord-022526-j9kg00qf 3142 3 can can MD cord-022526-j9kg00qf 3142 4 vary vary VB cord-022526-j9kg00qf 3142 5 from from IN cord-022526-j9kg00qf 3142 6 anorexia anorexia NN cord-022526-j9kg00qf 3142 7 and and CC cord-022526-j9kg00qf 3142 8 weight weight NN cord-022526-j9kg00qf 3142 9 loss loss NN cord-022526-j9kg00qf 3142 10 to to IN cord-022526-j9kg00qf 3142 11 those those DT cord-022526-j9kg00qf 3142 12 consistent consistent JJ cord-022526-j9kg00qf 3142 13 with with IN cord-022526-j9kg00qf 3142 14 severe severe JJ cord-022526-j9kg00qf 3142 15 abdominal abdominal JJ cord-022526-j9kg00qf 3142 16 pain pain NN cord-022526-j9kg00qf 3142 17 . . . cord-022526-j9kg00qf 3143 1 In in IN cord-022526-j9kg00qf 3143 2 severe severe JJ cord-022526-j9kg00qf 3143 3 cases case NNS cord-022526-j9kg00qf 3143 4 , , , cord-022526-j9kg00qf 3143 5 spontaneous spontaneous JJ cord-022526-j9kg00qf 3143 6 reflux reflux NN cord-022526-j9kg00qf 3143 7 may may MD cord-022526-j9kg00qf 3143 8 occur occur VB cord-022526-j9kg00qf 3143 9 , , , cord-022526-j9kg00qf 3143 10 with with IN cord-022526-j9kg00qf 3143 11 gastric gastric JJ cord-022526-j9kg00qf 3143 12 contents content NNS cord-022526-j9kg00qf 3143 13 visible visible JJ cord-022526-j9kg00qf 3143 14 at at IN cord-022526-j9kg00qf 3143 15 the the DT cord-022526-j9kg00qf 3143 16 nares naris NNS cord-022526-j9kg00qf 3143 17 . . . cord-022526-j9kg00qf 3144 1 In in IN cord-022526-j9kg00qf 3144 2 cases case NNS cord-022526-j9kg00qf 3144 3 of of IN cord-022526-j9kg00qf 3144 4 acute acute JJ cord-022526-j9kg00qf 3144 5 severe severe JJ cord-022526-j9kg00qf 3144 6 abdominal abdominal JJ cord-022526-j9kg00qf 3144 7 pain pain NN cord-022526-j9kg00qf 3144 8 , , , cord-022526-j9kg00qf 3144 9 one one CD cord-022526-j9kg00qf 3144 10 often often RB cord-022526-j9kg00qf 3144 11 makes make VBZ cord-022526-j9kg00qf 3144 12 a a DT cord-022526-j9kg00qf 3144 13 diagnosis diagnosis NN cord-022526-j9kg00qf 3144 14 during during IN cord-022526-j9kg00qf 3144 15 exploratory exploratory JJ cord-022526-j9kg00qf 3144 16 celiotomy celiotomy NN cord-022526-j9kg00qf 3144 17 . . . cord-022526-j9kg00qf 3145 1 In in IN cord-022526-j9kg00qf 3145 2 animals animal NNS cord-022526-j9kg00qf 3145 3 not not RB cord-022526-j9kg00qf 3145 4 exhibiting exhibit VBG cord-022526-j9kg00qf 3145 5 signs sign NNS cord-022526-j9kg00qf 3145 6 of of IN cord-022526-j9kg00qf 3145 7 colic colic NN cord-022526-j9kg00qf 3145 8 warranting warrant VBG cord-022526-j9kg00qf 3145 9 surgical surgical JJ cord-022526-j9kg00qf 3145 10 intervention intervention NN cord-022526-j9kg00qf 3145 11 , , , cord-022526-j9kg00qf 3145 12 an an DT cord-022526-j9kg00qf 3145 13 endoscopic endoscopic JJ cord-022526-j9kg00qf 3145 14 finding finding NN cord-022526-j9kg00qf 3145 15 of of IN cord-022526-j9kg00qf 3145 16 a a DT cord-022526-j9kg00qf 3145 17 full full JJ cord-022526-j9kg00qf 3145 18 stomach stomach NN cord-022526-j9kg00qf 3145 19 after after IN cord-022526-j9kg00qf 3145 20 a a DT cord-022526-j9kg00qf 3145 21 normally normally RB cord-022526-j9kg00qf 3145 22 adequate adequate JJ cord-022526-j9kg00qf 3145 23 fast fast RB cord-022526-j9kg00qf 3145 24 ( ( -LRB- cord-022526-j9kg00qf 3145 25 18 18 CD cord-022526-j9kg00qf 3145 26 to to TO cord-022526-j9kg00qf 3145 27 24 24 CD cord-022526-j9kg00qf 3145 28 hours hour NNS cord-022526-j9kg00qf 3145 29 ) ) -RRB- cord-022526-j9kg00qf 3145 30 often often RB cord-022526-j9kg00qf 3145 31 can can MD cord-022526-j9kg00qf 3145 32 confirm confirm VB cord-022526-j9kg00qf 3145 33 the the DT cord-022526-j9kg00qf 3145 34 diagnosis diagnosis NN cord-022526-j9kg00qf 3145 35 . . . cord-022526-j9kg00qf 3146 1 Abdominal abdominal JJ cord-022526-j9kg00qf 3146 2 radiographs radiograph NNS cord-022526-j9kg00qf 3146 3 are be VBP cord-022526-j9kg00qf 3146 4 reserved reserve VBN cord-022526-j9kg00qf 3146 5 for for IN cord-022526-j9kg00qf 3146 6 smaller small JJR cord-022526-j9kg00qf 3146 7 horses horse NNS cord-022526-j9kg00qf 3146 8 and and CC cord-022526-j9kg00qf 3146 9 ponies pony NNS cord-022526-j9kg00qf 3146 10 . . . cord-022526-j9kg00qf 3147 1 In in IN cord-022526-j9kg00qf 3147 2 addition addition NN cord-022526-j9kg00qf 3147 3 to to IN cord-022526-j9kg00qf 3147 4 pain pain NN cord-022526-j9kg00qf 3147 5 management management NN cord-022526-j9kg00qf 3147 6 , , , cord-022526-j9kg00qf 3147 7 specific specific JJ cord-022526-j9kg00qf 3147 8 treatment treatment NN cord-022526-j9kg00qf 3147 9 consists consist VBZ cord-022526-j9kg00qf 3147 10 of of IN cord-022526-j9kg00qf 3147 11 gastric gastric JJ cord-022526-j9kg00qf 3147 12 lavage lavage NN cord-022526-j9kg00qf 3147 13 via via IN cord-022526-j9kg00qf 3147 14 nasogastric nasogastric JJ cord-022526-j9kg00qf 3147 15 intubation intubation NN cord-022526-j9kg00qf 3147 16 or or CC cord-022526-j9kg00qf 3147 17 massage massage NN cord-022526-j9kg00qf 3147 18 and and CC cord-022526-j9kg00qf 3147 19 injection injection NN cord-022526-j9kg00qf 3147 20 of of IN cord-022526-j9kg00qf 3147 21 fluid fluid NN cord-022526-j9kg00qf 3147 22 to to TO cord-022526-j9kg00qf 3147 23 soften soften VB cord-022526-j9kg00qf 3147 24 the the DT cord-022526-j9kg00qf 3147 25 impaction impaction NN cord-022526-j9kg00qf 3147 26 during during IN cord-022526-j9kg00qf 3147 27 laparotomy laparotomy NN cord-022526-j9kg00qf 3147 28 . . . cord-022526-j9kg00qf 3148 1 [ [ -LRB- cord-022526-j9kg00qf 3148 2 98 98 CD cord-022526-j9kg00qf 3148 3 ] ] -RRB- cord-022526-j9kg00qf 3148 4 [ [ -LRB- cord-022526-j9kg00qf 3148 5 99 99 CD cord-022526-j9kg00qf 3148 6 ] ] -RRB- cord-022526-j9kg00qf 3149 1 [ [ -LRB- cord-022526-j9kg00qf 3149 2 100 100 CD cord-022526-j9kg00qf 3149 3 ] ] -RRB- cord-022526-j9kg00qf 3149 4 _SP cord-022526-j9kg00qf 3149 5 Nonulcerative Nonulcerative NNP cord-022526-j9kg00qf 3149 6 gastritis gastritis NN cord-022526-j9kg00qf 3149 7 rarely rarely RB cord-022526-j9kg00qf 3149 8 occurs occur VBZ cord-022526-j9kg00qf 3149 9 in in IN cord-022526-j9kg00qf 3149 10 the the DT cord-022526-j9kg00qf 3149 11 horse horse NN cord-022526-j9kg00qf 3149 12 ; ; : cord-022526-j9kg00qf 3149 13 however however RB cord-022526-j9kg00qf 3149 14 , , , cord-022526-j9kg00qf 3149 15 a a DT cord-022526-j9kg00qf 3149 16 single single JJ cord-022526-j9kg00qf 3149 17 case case NN cord-022526-j9kg00qf 3149 18 of of IN cord-022526-j9kg00qf 3149 19 emphysematous emphysematous JJ cord-022526-j9kg00qf 3149 20 gastritis gastritis NN cord-022526-j9kg00qf 3149 21 caused cause VBN cord-022526-j9kg00qf 3149 22 by by IN cord-022526-j9kg00qf 3149 23 Clostridium clostridium NN cord-022526-j9kg00qf 3149 24 perfringens perfringen NNS cord-022526-j9kg00qf 3149 25 has have VBZ cord-022526-j9kg00qf 3149 26 been be VBN cord-022526-j9kg00qf 3149 27 reported report VBN cord-022526-j9kg00qf 3149 28 . . . cord-022526-j9kg00qf 3150 1 101 101 CD cord-022526-j9kg00qf 3150 2 mimic mimic VBP cord-022526-j9kg00qf 3150 3 that that DT cord-022526-j9kg00qf 3150 4 of of IN cord-022526-j9kg00qf 3150 5 a a DT cord-022526-j9kg00qf 3150 6 strangulating strangulating JJ cord-022526-j9kg00qf 3150 7 or or CC cord-022526-j9kg00qf 3150 8 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 3150 9 small small JJ cord-022526-j9kg00qf 3150 10 intestinal intestinal JJ cord-022526-j9kg00qf 3150 11 obstruction obstruction NN cord-022526-j9kg00qf 3150 12 , , , cord-022526-j9kg00qf 3150 13 so so RB cord-022526-j9kg00qf 3150 14 distinguishing distinguish VBG cord-022526-j9kg00qf 3150 15 between between IN cord-022526-j9kg00qf 3150 16 the the DT cord-022526-j9kg00qf 3150 17 two two CD cord-022526-j9kg00qf 3150 18 syndromes syndrome NNS cord-022526-j9kg00qf 3150 19 is be VBZ cord-022526-j9kg00qf 3150 20 important important JJ cord-022526-j9kg00qf 3150 21 because because IN cord-022526-j9kg00qf 3150 22 appropriate appropriate JJ cord-022526-j9kg00qf 3150 23 treatment treatment NN cord-022526-j9kg00qf 3150 24 of of IN cord-022526-j9kg00qf 3150 25 small small JJ cord-022526-j9kg00qf 3150 26 intestinal intestinal JJ cord-022526-j9kg00qf 3150 27 obstruction obstruction NN cord-022526-j9kg00qf 3150 28 usually usually RB cord-022526-j9kg00qf 3150 29 requires require VBZ cord-022526-j9kg00qf 3150 30 surgical surgical JJ cord-022526-j9kg00qf 3150 31 intervention intervention NN cord-022526-j9kg00qf 3150 32 . . . cord-022526-j9kg00qf 3151 1 Studies study NNS cord-022526-j9kg00qf 3151 2 suggest suggest VBP cord-022526-j9kg00qf 3151 3 that that IN cord-022526-j9kg00qf 3151 4 the the DT cord-022526-j9kg00qf 3151 5 survival survival NN cord-022526-j9kg00qf 3151 6 rate rate NN cord-022526-j9kg00qf 3151 7 for for IN cord-022526-j9kg00qf 3151 8 horses horse NNS cord-022526-j9kg00qf 3151 9 with with IN cord-022526-j9kg00qf 3151 10 DPJ dpj NN cord-022526-j9kg00qf 3151 11 that that WDT cord-022526-j9kg00qf 3151 12 endured endure VBD cord-022526-j9kg00qf 3151 13 surgical surgical JJ cord-022526-j9kg00qf 3151 14 exploratory exploratory JJ cord-022526-j9kg00qf 3151 15 laparotomy laparotomy NN cord-022526-j9kg00qf 3151 16 was be VBD cord-022526-j9kg00qf 3151 17 poor poor JJ cord-022526-j9kg00qf 3151 18 compared compare VBN cord-022526-j9kg00qf 3151 19 with with IN cord-022526-j9kg00qf 3151 20 those those DT cord-022526-j9kg00qf 3151 21 treated treat VBN cord-022526-j9kg00qf 3151 22 medically medically RB cord-022526-j9kg00qf 3151 23 , , , cord-022526-j9kg00qf 3151 24 although although IN cord-022526-j9kg00qf 3151 25 differences difference NNS cord-022526-j9kg00qf 3151 26 in in IN cord-022526-j9kg00qf 3151 27 disease disease NN cord-022526-j9kg00qf 3151 28 severity severity NN cord-022526-j9kg00qf 3151 29 may may MD cord-022526-j9kg00qf 3151 30 have have VB cord-022526-j9kg00qf 3151 31 accounted account VBN cord-022526-j9kg00qf 3151 32 for for IN cord-022526-j9kg00qf 3151 33 the the DT cord-022526-j9kg00qf 3151 34 results result NNS cord-022526-j9kg00qf 3151 35 in in IN cord-022526-j9kg00qf 3151 36 these these DT cord-022526-j9kg00qf 3151 37 early early JJ cord-022526-j9kg00qf 3151 38 reports report NNS cord-022526-j9kg00qf 3151 39 . . . cord-022526-j9kg00qf 3152 1 1 1 CD cord-022526-j9kg00qf 3152 2 , , , cord-022526-j9kg00qf 3152 3 2 2 CD cord-022526-j9kg00qf 3153 1 The the DT cord-022526-j9kg00qf 3153 2 clinical clinical JJ cord-022526-j9kg00qf 3153 3 syndrome syndrome NN cord-022526-j9kg00qf 3153 4 of of IN cord-022526-j9kg00qf 3153 5 DPJ DPJ NNP cord-022526-j9kg00qf 3153 6 was be VBD cord-022526-j9kg00qf 3153 7 well well RB cord-022526-j9kg00qf 3153 8 described describe VBN cord-022526-j9kg00qf 3153 9 in in IN cord-022526-j9kg00qf 3153 10 the the DT cord-022526-j9kg00qf 3153 11 1980s 1980 NNS cord-022526-j9kg00qf 3153 12 , , , cord-022526-j9kg00qf 3153 13 and and CC cord-022526-j9kg00qf 3153 14 although although IN cord-022526-j9kg00qf 3153 15 recognized recognize VBN cord-022526-j9kg00qf 3153 16 by by IN cord-022526-j9kg00qf 3153 17 its -PRON- PRP$ cord-022526-j9kg00qf 3153 18 classical classical JJ cord-022526-j9kg00qf 3153 19 presentation presentation NN cord-022526-j9kg00qf 3153 20 , , , cord-022526-j9kg00qf 3153 21 varying vary VBG cord-022526-j9kg00qf 3153 22 degrees degree NNS cord-022526-j9kg00qf 3153 23 of of IN cord-022526-j9kg00qf 3153 24 focal focal JJ cord-022526-j9kg00qf 3153 25 intestinal intestinal JJ cord-022526-j9kg00qf 3153 26 and and CC cord-022526-j9kg00qf 3153 27 systemic systemic JJ cord-022526-j9kg00qf 3153 28 illness illness NN cord-022526-j9kg00qf 3153 29 may may MD cord-022526-j9kg00qf 3153 30 occur occur VB cord-022526-j9kg00qf 3153 31 . . . cord-022526-j9kg00qf 3154 1 1 1 LS cord-022526-j9kg00qf 3154 2 - - SYM cord-022526-j9kg00qf 3154 3 4 4 CD cord-022526-j9kg00qf 3154 4 DPJ dpj NN cord-022526-j9kg00qf 3154 5 usually usually RB cord-022526-j9kg00qf 3154 6 occurs occur VBZ cord-022526-j9kg00qf 3154 7 alone alone RB cord-022526-j9kg00qf 3154 8 but but CC cord-022526-j9kg00qf 3154 9 can can MD cord-022526-j9kg00qf 3154 10 occur occur VB cord-022526-j9kg00qf 3154 11 along along IN cord-022526-j9kg00qf 3154 12 with with IN cord-022526-j9kg00qf 3154 13 gastritis gastritis NN cord-022526-j9kg00qf 3154 14 , , , cord-022526-j9kg00qf 3154 15 ileitis ileitis NNP cord-022526-j9kg00qf 3154 16 , , , cord-022526-j9kg00qf 3154 17 typhlitis typhlitis NNP cord-022526-j9kg00qf 3154 18 , , , cord-022526-j9kg00qf 3154 19 and and CC cord-022526-j9kg00qf 3154 20 or or CC cord-022526-j9kg00qf 3154 21 colitis colitis NN cord-022526-j9kg00qf 3154 22 . . . cord-022526-j9kg00qf 3155 1 Typical typical JJ cord-022526-j9kg00qf 3155 2 pathologic pathologic JJ cord-022526-j9kg00qf 3155 3 findings finding NNS cord-022526-j9kg00qf 3155 4 in in IN cord-022526-j9kg00qf 3155 5 horses horse NNS cord-022526-j9kg00qf 3155 6 with with IN cord-022526-j9kg00qf 3155 7 DPJ dpj NN cord-022526-j9kg00qf 3155 8 include include VBP cord-022526-j9kg00qf 3155 9 involvement involvement NN cord-022526-j9kg00qf 3155 10 of of IN cord-022526-j9kg00qf 3155 11 the the DT cord-022526-j9kg00qf 3155 12 duodenum duodenum NN cord-022526-j9kg00qf 3155 13 and and CC cord-022526-j9kg00qf 3155 14 usually usually RB cord-022526-j9kg00qf 3155 15 the the DT cord-022526-j9kg00qf 3155 16 proximal proximal JJ cord-022526-j9kg00qf 3155 17 jejunum jejunum NNS cord-022526-j9kg00qf 3155 18 . . . cord-022526-j9kg00qf 3156 1 3 3 LS cord-022526-j9kg00qf 3157 1 The the DT cord-022526-j9kg00qf 3157 2 ileum ileum NN cord-022526-j9kg00qf 3157 3 and and CC cord-022526-j9kg00qf 3157 4 large large JJ cord-022526-j9kg00qf 3157 5 colon colon NN cord-022526-j9kg00qf 3157 6 usually usually RB cord-022526-j9kg00qf 3157 7 are be VBP cord-022526-j9kg00qf 3157 8 determined determined JJ cord-022526-j9kg00qf 3157 9 to to TO cord-022526-j9kg00qf 3157 10 be be VB cord-022526-j9kg00qf 3157 11 grossly grossly RB cord-022526-j9kg00qf 3157 12 normal normal JJ cord-022526-j9kg00qf 3157 13 . . . cord-022526-j9kg00qf 3158 1 Gastric gastric JJ cord-022526-j9kg00qf 3158 2 distention distention NN cord-022526-j9kg00qf 3158 3 is be VBZ cord-022526-j9kg00qf 3158 4 a a DT cord-022526-j9kg00qf 3158 5 common common JJ cord-022526-j9kg00qf 3158 6 finding finding NN cord-022526-j9kg00qf 3158 7 and and CC cord-022526-j9kg00qf 3158 8 is be VBZ cord-022526-j9kg00qf 3158 9 thought think VBN cord-022526-j9kg00qf 3158 10 to to TO cord-022526-j9kg00qf 3158 11 be be VB cord-022526-j9kg00qf 3158 12 caused cause VBN cord-022526-j9kg00qf 3158 13 by by IN cord-022526-j9kg00qf 3158 14 hypersecretory hypersecretory NNP cord-022526-j9kg00qf 3158 15 mechanisms mechanism NNS cord-022526-j9kg00qf 3158 16 in in IN cord-022526-j9kg00qf 3158 17 the the DT cord-022526-j9kg00qf 3158 18 proximal proximal JJ cord-022526-j9kg00qf 3158 19 small small JJ cord-022526-j9kg00qf 3158 20 intestine intestine NN cord-022526-j9kg00qf 3158 21 and and CC cord-022526-j9kg00qf 3158 22 a a DT cord-022526-j9kg00qf 3158 23 functional functional JJ cord-022526-j9kg00qf 3158 24 ileus ileus NN cord-022526-j9kg00qf 3158 25 of of IN cord-022526-j9kg00qf 3158 26 affected affected JJ cord-022526-j9kg00qf 3158 27 enteric enteric JJ cord-022526-j9kg00qf 3158 28 segments segment NNS cord-022526-j9kg00qf 3158 29 . . . cord-022526-j9kg00qf 3159 1 The the DT cord-022526-j9kg00qf 3159 2 small small JJ cord-022526-j9kg00qf 3159 3 intestine intestine NN cord-022526-j9kg00qf 3159 4 may may MD cord-022526-j9kg00qf 3159 5 be be VB cord-022526-j9kg00qf 3159 6 5 5 CD cord-022526-j9kg00qf 3159 7 to to TO cord-022526-j9kg00qf 3159 8 7 7 CD cord-022526-j9kg00qf 3159 9 cm cm NNS cord-022526-j9kg00qf 3159 10 in in IN cord-022526-j9kg00qf 3159 11 diameter diameter NN cord-022526-j9kg00qf 3159 12 because because IN cord-022526-j9kg00qf 3159 13 of of IN cord-022526-j9kg00qf 3159 14 fluid fluid JJ cord-022526-j9kg00qf 3159 15 distention distention NN cord-022526-j9kg00qf 3159 16 with with IN cord-022526-j9kg00qf 3159 17 malodorous malodorous JJ cord-022526-j9kg00qf 3159 18 , , , cord-022526-j9kg00qf 3159 19 red red JJ cord-022526-j9kg00qf 3159 20 to to IN cord-022526-j9kg00qf 3159 21 brown brown JJ cord-022526-j9kg00qf 3159 22 - - HYPH cord-022526-j9kg00qf 3159 23 red red JJ cord-022526-j9kg00qf 3159 24 intralumenal intralumenal JJ cord-022526-j9kg00qf 3159 25 fluid fluid JJ cord-022526-j9kg00qf 3159 26 accumulation accumulation NN cord-022526-j9kg00qf 3159 27 . . . cord-022526-j9kg00qf 3160 1 Duodenal duodenal JJ cord-022526-j9kg00qf 3160 2 ( ( -LRB- cord-022526-j9kg00qf 3160 3 and and CC cord-022526-j9kg00qf 3160 4 jejunal jejunal NNP cord-022526-j9kg00qf 3160 5 ) ) -RRB- cord-022526-j9kg00qf 3161 1 serosal serosal NNP cord-022526-j9kg00qf 3161 2 surfaces surface NNS cord-022526-j9kg00qf 3161 3 may may MD cord-022526-j9kg00qf 3161 4 have have VB cord-022526-j9kg00qf 3161 5 varying vary VBG cord-022526-j9kg00qf 3161 6 degrees degree NNS cord-022526-j9kg00qf 3161 7 and and CC cord-022526-j9kg00qf 3161 8 distribution distribution NN cord-022526-j9kg00qf 3161 9 of of IN cord-022526-j9kg00qf 3161 10 bright bright JJ cord-022526-j9kg00qf 3161 11 - - HYPH cord-022526-j9kg00qf 3161 12 red red JJ cord-022526-j9kg00qf 3161 13 to to IN cord-022526-j9kg00qf 3161 14 dark dark JJ cord-022526-j9kg00qf 3161 15 - - HYPH cord-022526-j9kg00qf 3161 16 red red JJ cord-022526-j9kg00qf 3161 17 petechial petechial NN cord-022526-j9kg00qf 3161 18 and and CC cord-022526-j9kg00qf 3161 19 ecchymotic ecchymotic JJ cord-022526-j9kg00qf 3161 20 hemorrhages hemorrhage NNS cord-022526-j9kg00qf 3161 21 and and CC cord-022526-j9kg00qf 3161 22 yellow yellow JJ cord-022526-j9kg00qf 3161 23 to to IN cord-022526-j9kg00qf 3161 24 white white JJ cord-022526-j9kg00qf 3161 25 streaks streak NNS cord-022526-j9kg00qf 3161 26 . . . cord-022526-j9kg00qf 3162 1 The the DT cord-022526-j9kg00qf 3162 2 enteric enteric JJ cord-022526-j9kg00qf 3162 3 mucosal mucosal JJ cord-022526-j9kg00qf 3162 4 surfaces surface NNS cord-022526-j9kg00qf 3162 5 are be VBP cord-022526-j9kg00qf 3162 6 usually usually RB cord-022526-j9kg00qf 3162 7 hyperemic hyperemic JJ cord-022526-j9kg00qf 3162 8 and and CC cord-022526-j9kg00qf 3162 9 have have VBP cord-022526-j9kg00qf 3162 10 varying vary VBG cord-022526-j9kg00qf 3162 11 degrees degree NNS cord-022526-j9kg00qf 3162 12 of of IN cord-022526-j9kg00qf 3162 13 petechiation petechiation NN cord-022526-j9kg00qf 3162 14 and and CC cord-022526-j9kg00qf 3162 15 ulceration ulceration NN cord-022526-j9kg00qf 3162 16 . . . cord-022526-j9kg00qf 3163 1 Microscopically microscopically RB cord-022526-j9kg00qf 3163 2 , , , cord-022526-j9kg00qf 3163 3 the the DT cord-022526-j9kg00qf 3163 4 most most RBS cord-022526-j9kg00qf 3163 5 severe severe JJ cord-022526-j9kg00qf 3163 6 lesions lesion NNS cord-022526-j9kg00qf 3163 7 have have VBP cord-022526-j9kg00qf 3163 8 been be VBN cord-022526-j9kg00qf 3163 9 located locate VBN cord-022526-j9kg00qf 3163 10 in in IN cord-022526-j9kg00qf 3163 11 the the DT cord-022526-j9kg00qf 3163 12 duodenum duodenum NN cord-022526-j9kg00qf 3163 13 and and CC cord-022526-j9kg00qf 3163 14 proximal proximal JJ cord-022526-j9kg00qf 3163 15 jejunum jejunum NNS cord-022526-j9kg00qf 3163 16 but but CC cord-022526-j9kg00qf 3163 17 may may MD cord-022526-j9kg00qf 3163 18 extend extend VB cord-022526-j9kg00qf 3163 19 proximally proximally RB cord-022526-j9kg00qf 3163 20 to to IN cord-022526-j9kg00qf 3163 21 the the DT cord-022526-j9kg00qf 3163 22 gastric gastric JJ cord-022526-j9kg00qf 3163 23 mucosa mucosa NN cord-022526-j9kg00qf 3163 24 and and CC cord-022526-j9kg00qf 3163 25 aborally aborally RB cord-022526-j9kg00qf 3163 26 to to IN cord-022526-j9kg00qf 3163 27 the the DT cord-022526-j9kg00qf 3163 28 large large JJ cord-022526-j9kg00qf 3163 29 intestinal intestinal JJ cord-022526-j9kg00qf 3163 30 mucosa mucosa NN cord-022526-j9kg00qf 3163 31 and and CC cord-022526-j9kg00qf 3163 32 submucosa submucosa NNP cord-022526-j9kg00qf 3163 33 . . . cord-022526-j9kg00qf 3164 1 3 3 CD cord-022526-j9kg00qf 3164 2 Microscopic microscopic JJ cord-022526-j9kg00qf 3164 3 lesions lesion NNS cord-022526-j9kg00qf 3164 4 consist consist VBP cord-022526-j9kg00qf 3164 5 of of IN cord-022526-j9kg00qf 3164 6 varying vary VBG cord-022526-j9kg00qf 3164 7 degrees degree NNS cord-022526-j9kg00qf 3164 8 of of IN cord-022526-j9kg00qf 3164 9 mucosal mucosal NN cord-022526-j9kg00qf 3164 10 and and CC cord-022526-j9kg00qf 3164 11 submucosal submucosal NNP cord-022526-j9kg00qf 3164 12 hyperemia hyperemia NNP cord-022526-j9kg00qf 3164 13 and and CC cord-022526-j9kg00qf 3164 14 edema edema NN cord-022526-j9kg00qf 3164 15 . . . cord-022526-j9kg00qf 3165 1 More More JJR cord-022526-j9kg00qf 3165 2 severe severe JJ cord-022526-j9kg00qf 3165 3 lesions lesion NNS cord-022526-j9kg00qf 3165 4 include include VBP cord-022526-j9kg00qf 3165 5 villus villus NN cord-022526-j9kg00qf 3165 6 degeneration degeneration NN cord-022526-j9kg00qf 3165 7 with with IN cord-022526-j9kg00qf 3165 8 necrosis necrosis NN cord-022526-j9kg00qf 3165 9 and and CC cord-022526-j9kg00qf 3165 10 more more RBR cord-022526-j9kg00qf 3165 11 severely severely RB cord-022526-j9kg00qf 3165 12 , , , cord-022526-j9kg00qf 3165 13 sloughing slough VBG cord-022526-j9kg00qf 3165 14 of of IN cord-022526-j9kg00qf 3165 15 villous villous JJ cord-022526-j9kg00qf 3165 16 epithelium epithelium NN cord-022526-j9kg00qf 3165 17 . . . cord-022526-j9kg00qf 3166 1 The the DT cord-022526-j9kg00qf 3166 2 lamina lamina JJ cord-022526-j9kg00qf 3166 3 propria propria NN cord-022526-j9kg00qf 3166 4 , , , cord-022526-j9kg00qf 3166 5 mucosa mucosa JJ cord-022526-j9kg00qf 3166 6 , , , cord-022526-j9kg00qf 3166 7 and and CC cord-022526-j9kg00qf 3166 8 submucosa submucosa NNP cord-022526-j9kg00qf 3166 9 may may MD cord-022526-j9kg00qf 3166 10 have have VB cord-022526-j9kg00qf 3166 11 varying vary VBG cord-022526-j9kg00qf 3166 12 degrees degree NNS cord-022526-j9kg00qf 3166 13 of of IN cord-022526-j9kg00qf 3166 14 granulocyte granulocyte NN cord-022526-j9kg00qf 3166 15 infiltration infiltration NN cord-022526-j9kg00qf 3166 16 ( ( -LRB- cord-022526-j9kg00qf 3166 17 predominantly predominantly RB cord-022526-j9kg00qf 3166 18 neutrophils neutrophil NNS cord-022526-j9kg00qf 3166 19 ) ) -RRB- cord-022526-j9kg00qf 3166 20 , , , cord-022526-j9kg00qf 3166 21 and and CC cord-022526-j9kg00qf 3166 22 the the DT cord-022526-j9kg00qf 3166 23 muscular muscular JJ cord-022526-j9kg00qf 3166 24 layers layer NNS cord-022526-j9kg00qf 3166 25 and and CC cord-022526-j9kg00qf 3166 26 serosal serosal NN cord-022526-j9kg00qf 3166 27 surfaces surface NNS cord-022526-j9kg00qf 3166 28 contain contain VBP cord-022526-j9kg00qf 3166 29 small small JJ cord-022526-j9kg00qf 3166 30 hemorrhages hemorrhage NNS cord-022526-j9kg00qf 3166 31 . . . cord-022526-j9kg00qf 3167 1 Proximal proximal JJ cord-022526-j9kg00qf 3167 2 small small JJ cord-022526-j9kg00qf 3167 3 intestinal intestinal JJ cord-022526-j9kg00qf 3167 4 serosal serosal NN cord-022526-j9kg00qf 3167 5 fibrinopurulent fibrinopurulent NNP cord-022526-j9kg00qf 3167 6 exudate exudate NNP cord-022526-j9kg00qf 3167 7 is be VBZ cord-022526-j9kg00qf 3167 8 a a DT cord-022526-j9kg00qf 3167 9 common common JJ cord-022526-j9kg00qf 3167 10 finding finding NN cord-022526-j9kg00qf 3167 11 in in IN cord-022526-j9kg00qf 3167 12 the the DT cord-022526-j9kg00qf 3167 13 more more RBR cord-022526-j9kg00qf 3167 14 severe severe JJ cord-022526-j9kg00qf 3167 15 cases case NNS cord-022526-j9kg00qf 3167 16 ; ; : cord-022526-j9kg00qf 3167 17 therefore therefore RB cord-022526-j9kg00qf 3167 18 the the DT cord-022526-j9kg00qf 3167 19 term term NN cord-022526-j9kg00qf 3167 20 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 3167 21 fibrinonecrotic fibrinonecrotic JJ cord-022526-j9kg00qf 3167 22 duodenitis duodenitis NN cord-022526-j9kg00qf 3167 23 - - HYPH cord-022526-j9kg00qf 3167 24 proximal proximal JJ cord-022526-j9kg00qf 3167 25 jejunitis jejunitis NN cord-022526-j9kg00qf 3167 26 has have VBZ cord-022526-j9kg00qf 3167 27 been be VBN cord-022526-j9kg00qf 3167 28 suggested suggest VBN cord-022526-j9kg00qf 3167 29 as as IN cord-022526-j9kg00qf 3167 30 a a DT cord-022526-j9kg00qf 3167 31 more more RBR cord-022526-j9kg00qf 3167 32 descriptive descriptive JJ cord-022526-j9kg00qf 3167 33 name name NN cord-022526-j9kg00qf 3167 34 for for IN cord-022526-j9kg00qf 3167 35 this this DT cord-022526-j9kg00qf 3167 36 syndrome syndrome NN cord-022526-j9kg00qf 3167 37 . . . cord-022526-j9kg00qf 3168 1 Horses horse NNS cord-022526-j9kg00qf 3168 2 with with IN cord-022526-j9kg00qf 3168 3 DPJ dpj NN cord-022526-j9kg00qf 3168 4 often often RB cord-022526-j9kg00qf 3168 5 have have VBP cord-022526-j9kg00qf 3168 6 evidence evidence NN cord-022526-j9kg00qf 3168 7 of of IN cord-022526-j9kg00qf 3168 8 multiple multiple JJ cord-022526-j9kg00qf 3168 9 organ organ NN cord-022526-j9kg00qf 3168 10 involvement involvement NN cord-022526-j9kg00qf 3168 11 such such JJ cord-022526-j9kg00qf 3168 12 as as IN cord-022526-j9kg00qf 3168 13 hepatic hepatic JJ cord-022526-j9kg00qf 3168 14 changes change NNS cord-022526-j9kg00qf 3168 15 including include VBG cord-022526-j9kg00qf 3168 16 congestion congestion NN cord-022526-j9kg00qf 3168 17 and and CC cord-022526-j9kg00qf 3168 18 varying vary VBG cord-022526-j9kg00qf 3168 19 degrees degree NNS cord-022526-j9kg00qf 3168 20 of of IN cord-022526-j9kg00qf 3168 21 biliary biliary JJ cord-022526-j9kg00qf 3168 22 duct duct NN cord-022526-j9kg00qf 3168 23 hyperplasia hyperplasia NN cord-022526-j9kg00qf 3168 24 . . . cord-022526-j9kg00qf 3169 1 Additional additional JJ cord-022526-j9kg00qf 3169 2 systemic systemic JJ cord-022526-j9kg00qf 3169 3 involvement involvement NN cord-022526-j9kg00qf 3169 4 likely likely RB cord-022526-j9kg00qf 3169 5 is be VBZ cord-022526-j9kg00qf 3169 6 caused cause VBN cord-022526-j9kg00qf 3169 7 by by IN cord-022526-j9kg00qf 3169 8 endotoxin endotoxin NN cord-022526-j9kg00qf 3169 9 absorption absorption NN cord-022526-j9kg00qf 3169 10 , , , cord-022526-j9kg00qf 3169 11 metabolic metabolic JJ cord-022526-j9kg00qf 3169 12 imbalances imbalance NNS cord-022526-j9kg00qf 3169 13 such such JJ cord-022526-j9kg00qf 3169 14 as as IN cord-022526-j9kg00qf 3169 15 acidemia acidemia NN cord-022526-j9kg00qf 3169 16 , , , cord-022526-j9kg00qf 3169 17 and and CC cord-022526-j9kg00qf 3169 18 circulatory circulatory JJ cord-022526-j9kg00qf 3169 19 changes change NNS cord-022526-j9kg00qf 3169 20 . . . cord-022526-j9kg00qf 3170 1 The the DT cord-022526-j9kg00qf 3170 2 cause cause NN cord-022526-j9kg00qf 3170 3 of of IN cord-022526-j9kg00qf 3170 4 this this DT cord-022526-j9kg00qf 3170 5 syndrome syndrome NN cord-022526-j9kg00qf 3170 6 remains remain VBZ cord-022526-j9kg00qf 3170 7 an an DT cord-022526-j9kg00qf 3170 8 enigma enigma NN cord-022526-j9kg00qf 3170 9 ( ( -LRB- cord-022526-j9kg00qf 3170 10 much much RB cord-022526-j9kg00qf 3170 11 like like IN cord-022526-j9kg00qf 3170 12 the the DT cord-022526-j9kg00qf 3170 13 cause cause NN cord-022526-j9kg00qf 3170 14 of of IN cord-022526-j9kg00qf 3170 15 other other JJ cord-022526-j9kg00qf 3170 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 3170 17 conditions condition NNS cord-022526-j9kg00qf 3170 18 affecting affect VBG cord-022526-j9kg00qf 3170 19 the the DT cord-022526-j9kg00qf 3170 20 intestinal intestinal JJ cord-022526-j9kg00qf 3170 21 tract tract NN cord-022526-j9kg00qf 3170 22 ) ) -RRB- cord-022526-j9kg00qf 3170 23 . . . cord-022526-j9kg00qf 3171 1 Several several JJ cord-022526-j9kg00qf 3171 2 microorganisms microorganism NNS cord-022526-j9kg00qf 3171 3 have have VBP cord-022526-j9kg00qf 3171 4 been be VBN cord-022526-j9kg00qf 3171 5 implicated implicate VBN cord-022526-j9kg00qf 3171 6 as as IN cord-022526-j9kg00qf 3171 7 playing play VBG cord-022526-j9kg00qf 3171 8 a a DT cord-022526-j9kg00qf 3171 9 role role NN cord-022526-j9kg00qf 3171 10 in in IN cord-022526-j9kg00qf 3171 11 triggering trigger VBG cord-022526-j9kg00qf 3171 12 DPJ dpj NN cord-022526-j9kg00qf 3171 13 , , , cord-022526-j9kg00qf 3171 14 including include VBG cord-022526-j9kg00qf 3171 15 Clostridium clostridium NN cord-022526-j9kg00qf 3171 16 spp spp NNS cord-022526-j9kg00qf 3171 17 . . . cord-022526-j9kg00qf 3172 1 , , , cord-022526-j9kg00qf 3172 2 Salmonella Salmonella NNP cord-022526-j9kg00qf 3172 3 spp spp NNS cord-022526-j9kg00qf 3172 4 . . . cord-022526-j9kg00qf 3173 1 , , , cord-022526-j9kg00qf 3173 2 and and CC cord-022526-j9kg00qf 3173 3 some some DT cord-022526-j9kg00qf 3173 4 mycotoxins mycotoxin NNS cord-022526-j9kg00qf 3173 5 , , , cord-022526-j9kg00qf 3173 6 but but CC cord-022526-j9kg00qf 3173 7 efforts effort NNS cord-022526-j9kg00qf 3173 8 to to TO cord-022526-j9kg00qf 3173 9 reproduce reproduce VB cord-022526-j9kg00qf 3173 10 the the DT cord-022526-j9kg00qf 3173 11 syndrome syndrome NN cord-022526-j9kg00qf 3173 12 experimentally experimentally RB cord-022526-j9kg00qf 3173 13 have have VBP cord-022526-j9kg00qf 3173 14 been be VBN cord-022526-j9kg00qf 3173 15 futile futile JJ cord-022526-j9kg00qf 3173 16 . . . cord-022526-j9kg00qf 3174 1 5 5 LS cord-022526-j9kg00qf 3175 1 A a DT cord-022526-j9kg00qf 3175 2 recent recent JJ cord-022526-j9kg00qf 3175 3 dietary dietary JJ cord-022526-j9kg00qf 3175 4 change change NN cord-022526-j9kg00qf 3175 5 with with IN cord-022526-j9kg00qf 3175 6 an an DT cord-022526-j9kg00qf 3175 7 abrupt abrupt JJ cord-022526-j9kg00qf 3175 8 increase increase NN cord-022526-j9kg00qf 3175 9 in in IN cord-022526-j9kg00qf 3175 10 dietary dietary JJ cord-022526-j9kg00qf 3175 11 concentrate concentrate NN cord-022526-j9kg00qf 3175 12 level level NN cord-022526-j9kg00qf 3175 13 has have VBZ cord-022526-j9kg00qf 3175 14 been be VBN cord-022526-j9kg00qf 3175 15 suggested suggest VBN cord-022526-j9kg00qf 3175 16 to to TO cord-022526-j9kg00qf 3175 17 predispose predispose VB cord-022526-j9kg00qf 3175 18 a a DT cord-022526-j9kg00qf 3175 19 horse horse NN cord-022526-j9kg00qf 3175 20 to to IN cord-022526-j9kg00qf 3175 21 developing develop VBG cord-022526-j9kg00qf 3175 22 DPJ dpj NN cord-022526-j9kg00qf 3175 23 because because IN cord-022526-j9kg00qf 3175 24 of of IN cord-022526-j9kg00qf 3175 25 intraluminal intraluminal JJ cord-022526-j9kg00qf 3175 26 microbial microbial JJ cord-022526-j9kg00qf 3175 27 imbalances imbalance NNS cord-022526-j9kg00qf 3175 28 . . . cord-022526-j9kg00qf 3176 1 Two two CD cord-022526-j9kg00qf 3176 2 intracellular intracellular JJ cord-022526-j9kg00qf 3176 3 processes process NNS cord-022526-j9kg00qf 3176 4 control control VBP cord-022526-j9kg00qf 3176 5 intestinal intestinal JJ cord-022526-j9kg00qf 3176 6 secretion secretion NN cord-022526-j9kg00qf 3176 7 , , , cord-022526-j9kg00qf 3176 8 the the DT cord-022526-j9kg00qf 3176 9 cyclic cyclic JJ cord-022526-j9kg00qf 3176 10 nucleotide nucleotide NN cord-022526-j9kg00qf 3176 11 ( ( -LRB- cord-022526-j9kg00qf 3176 12 cyclic cyclic JJ cord-022526-j9kg00qf 3176 13 adenosine adenosine NN cord-022526-j9kg00qf 3176 14 monophosphate monophosphate NN cord-022526-j9kg00qf 3176 15 and and CC cord-022526-j9kg00qf 3176 16 cyclic cyclic JJ cord-022526-j9kg00qf 3176 17 guanosine guanosine NN cord-022526-j9kg00qf 3176 18 monophosphate monophosphate NN cord-022526-j9kg00qf 3176 19 ) ) -RRB- cord-022526-j9kg00qf 3176 20 and and CC cord-022526-j9kg00qf 3176 21 the the DT cord-022526-j9kg00qf 3176 22 calcium calcium NN cord-022526-j9kg00qf 3176 23 systems system NNS cord-022526-j9kg00qf 3176 24 . . . cord-022526-j9kg00qf 3177 1 6 6 CD cord-022526-j9kg00qf 3177 2 Agents agent NNS cord-022526-j9kg00qf 3177 3 ( ( -LRB- cord-022526-j9kg00qf 3177 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 3177 5 mediators mediator NNS cord-022526-j9kg00qf 3177 6 , , , cord-022526-j9kg00qf 3177 7 microorganisms microorganism NNS cord-022526-j9kg00qf 3177 8 , , , cord-022526-j9kg00qf 3177 9 toxic toxic JJ cord-022526-j9kg00qf 3177 10 agents agent NNS cord-022526-j9kg00qf 3177 11 ) ) -RRB- cord-022526-j9kg00qf 3177 12 can can MD cord-022526-j9kg00qf 3177 13 activate activate VB cord-022526-j9kg00qf 3177 14 adenyl adenyl NNP cord-022526-j9kg00qf 3177 15 cyclase cyclase NN cord-022526-j9kg00qf 3177 16 ( ( -LRB- cord-022526-j9kg00qf 3177 17 vasoactive vasoactive JJ cord-022526-j9kg00qf 3177 18 intestinal intestinal JJ cord-022526-j9kg00qf 3177 19 peptide peptide NN cord-022526-j9kg00qf 3177 20 , , , cord-022526-j9kg00qf 3177 21 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3177 22 E e NN cord-022526-j9kg00qf 3177 23 2 2 CD cord-022526-j9kg00qf 3177 24 ) ) -RRB- cord-022526-j9kg00qf 3177 25 or or CC cord-022526-j9kg00qf 3177 26 guanyl guanyl NNP cord-022526-j9kg00qf 3177 27 cyclase cyclase NN cord-022526-j9kg00qf 3177 28 ( ( -LRB- cord-022526-j9kg00qf 3177 29 bacterial bacterial JJ cord-022526-j9kg00qf 3177 30 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 3177 31 ) ) -RRB- cord-022526-j9kg00qf 3177 32 and and CC cord-022526-j9kg00qf 3177 33 induce induce VB cord-022526-j9kg00qf 3177 34 increases increase NNS cord-022526-j9kg00qf 3177 35 in in IN cord-022526-j9kg00qf 3177 36 cyclic cyclic JJ cord-022526-j9kg00qf 3177 37 adenosine adenosine NN cord-022526-j9kg00qf 3177 38 monophosphate monophosphate NN cord-022526-j9kg00qf 3177 39 and and CC cord-022526-j9kg00qf 3177 40 cyclic cyclic JJ cord-022526-j9kg00qf 3177 41 guanosine guanosine NN cord-022526-j9kg00qf 3177 42 monophosphate monophosphate NN cord-022526-j9kg00qf 3177 43 , , , cord-022526-j9kg00qf 3177 44 respectively respectively RB cord-022526-j9kg00qf 3177 45 . . . cord-022526-j9kg00qf 3178 1 This this DT cord-022526-j9kg00qf 3178 2 reaction reaction NN cord-022526-j9kg00qf 3178 3 causes cause VBZ cord-022526-j9kg00qf 3178 4 phosphorylation phosphorylation NN cord-022526-j9kg00qf 3178 5 of of IN cord-022526-j9kg00qf 3178 6 specific specific JJ cord-022526-j9kg00qf 3178 7 protein protein NN cord-022526-j9kg00qf 3178 8 kinases kinase NNS cord-022526-j9kg00qf 3178 9 , , , cord-022526-j9kg00qf 3178 10 which which WDT cord-022526-j9kg00qf 3178 11 induce induce VBP cord-022526-j9kg00qf 3178 12 the the DT cord-022526-j9kg00qf 3178 13 actual actual JJ cord-022526-j9kg00qf 3178 14 mucosal mucosal JJ cord-022526-j9kg00qf 3178 15 membrane membrane NN cord-022526-j9kg00qf 3178 16 transport transport NN cord-022526-j9kg00qf 3178 17 events event NNS cord-022526-j9kg00qf 3178 18 . . . cord-022526-j9kg00qf 3179 1 Increases increase NNS cord-022526-j9kg00qf 3179 2 in in IN cord-022526-j9kg00qf 3179 3 intracellular intracellular JJ cord-022526-j9kg00qf 3179 4 free free JJ cord-022526-j9kg00qf 3179 5 calcium calcium NN cord-022526-j9kg00qf 3179 6 may may MD cord-022526-j9kg00qf 3179 7 arise arise VB cord-022526-j9kg00qf 3179 8 from from IN cord-022526-j9kg00qf 3179 9 cyclic cyclic JJ cord-022526-j9kg00qf 3179 10 nucleotidedependent nucleotidedependent JJ cord-022526-j9kg00qf 3179 11 release release NN cord-022526-j9kg00qf 3179 12 of of IN cord-022526-j9kg00qf 3179 13 stored store VBN cord-022526-j9kg00qf 3179 14 calcium calcium NN cord-022526-j9kg00qf 3179 15 within within IN cord-022526-j9kg00qf 3179 16 the the DT cord-022526-j9kg00qf 3179 17 cell cell NN cord-022526-j9kg00qf 3179 18 or or CC cord-022526-j9kg00qf 3179 19 from from IN cord-022526-j9kg00qf 3179 20 increased increase VBN cord-022526-j9kg00qf 3179 21 calcium calcium NN cord-022526-j9kg00qf 3179 22 entry entry NN cord-022526-j9kg00qf 3179 23 across across IN cord-022526-j9kg00qf 3179 24 the the DT cord-022526-j9kg00qf 3179 25 cell cell NN cord-022526-j9kg00qf 3179 26 membrane membrane NN cord-022526-j9kg00qf 3179 27 . . . cord-022526-j9kg00qf 3180 1 7 7 CD cord-022526-j9kg00qf 3180 2 Calcium Calcium NNP cord-022526-j9kg00qf 3180 3 may may MD cord-022526-j9kg00qf 3180 4 act act VB cord-022526-j9kg00qf 3180 5 through through IN cord-022526-j9kg00qf 3180 6 calmodulin calmodulin NNP cord-022526-j9kg00qf 3180 7 , , , cord-022526-j9kg00qf 3180 8 which which WDT cord-022526-j9kg00qf 3180 9 then then RB cord-022526-j9kg00qf 3180 10 can can MD cord-022526-j9kg00qf 3180 11 activate activate VB cord-022526-j9kg00qf 3180 12 membrane membrane NN cord-022526-j9kg00qf 3180 13 - - HYPH cord-022526-j9kg00qf 3180 14 phosphorylating phosphorylate VBG cord-022526-j9kg00qf 3180 15 protein protein NN cord-022526-j9kg00qf 3180 16 kinases kinase NNS cord-022526-j9kg00qf 3180 17 . . . cord-022526-j9kg00qf 3181 1 The the DT cord-022526-j9kg00qf 3181 2 net net JJ cord-022526-j9kg00qf 3181 3 effect effect NN cord-022526-j9kg00qf 3181 4 is be VBZ cord-022526-j9kg00qf 3181 5 increased increase VBN cord-022526-j9kg00qf 3181 6 movement movement NN cord-022526-j9kg00qf 3181 7 of of IN cord-022526-j9kg00qf 3181 8 sodium sodium NN cord-022526-j9kg00qf 3181 9 and and CC cord-022526-j9kg00qf 3181 10 chloride chloride NN cord-022526-j9kg00qf 3181 11 into into IN cord-022526-j9kg00qf 3181 12 the the DT cord-022526-j9kg00qf 3181 13 mucosal mucosal JJ cord-022526-j9kg00qf 3181 14 cell cell NN cord-022526-j9kg00qf 3181 15 from from IN cord-022526-j9kg00qf 3181 16 the the DT cord-022526-j9kg00qf 3181 17 interstitium interstitium NN cord-022526-j9kg00qf 3181 18 , , , cord-022526-j9kg00qf 3181 19 with with IN cord-022526-j9kg00qf 3181 20 secretion secretion NN cord-022526-j9kg00qf 3181 21 of of IN cord-022526-j9kg00qf 3181 22 sodium sodium NN cord-022526-j9kg00qf 3181 23 and and CC cord-022526-j9kg00qf 3181 24 chloride chloride NN cord-022526-j9kg00qf 3181 25 into into IN cord-022526-j9kg00qf 3181 26 the the DT cord-022526-j9kg00qf 3181 27 intestinal intestinal JJ cord-022526-j9kg00qf 3181 28 lumen lumen NN cord-022526-j9kg00qf 3181 29 . . . cord-022526-j9kg00qf 3182 1 Water water NN cord-022526-j9kg00qf 3182 2 follows follow VBZ cord-022526-j9kg00qf 3182 3 the the DT cord-022526-j9kg00qf 3182 4 directional directional JJ cord-022526-j9kg00qf 3182 5 flux flux NN cord-022526-j9kg00qf 3182 6 of of IN cord-022526-j9kg00qf 3182 7 sodium sodium NN cord-022526-j9kg00qf 3182 8 and and CC cord-022526-j9kg00qf 3182 9 chloride chloride NN cord-022526-j9kg00qf 3182 10 through through IN cord-022526-j9kg00qf 3182 11 highly highly RB cord-022526-j9kg00qf 3182 12 permeable permeable JJ cord-022526-j9kg00qf 3182 13 intercellular intercellular JJ cord-022526-j9kg00qf 3182 14 spaces space NNS cord-022526-j9kg00qf 3182 15 . . . cord-022526-j9kg00qf 3183 1 Several several JJ cord-022526-j9kg00qf 3183 2 bacterial bacterial JJ cord-022526-j9kg00qf 3183 3 toxins toxin NNS cord-022526-j9kg00qf 3183 4 and and CC cord-022526-j9kg00qf 3183 5 endogenous endogenous JJ cord-022526-j9kg00qf 3183 6 mediators mediator NNS cord-022526-j9kg00qf 3183 7 can can MD cord-022526-j9kg00qf 3183 8 cause cause VB cord-022526-j9kg00qf 3183 9 active active JJ cord-022526-j9kg00qf 3183 10 secretion secretion NN cord-022526-j9kg00qf 3183 11 and and CC cord-022526-j9kg00qf 3183 12 contribute contribute VB cord-022526-j9kg00qf 3183 13 to to IN cord-022526-j9kg00qf 3183 14 a a DT cord-022526-j9kg00qf 3183 15 synergistic synergistic JJ cord-022526-j9kg00qf 3183 16 mucosal mucosal JJ cord-022526-j9kg00qf 3183 17 secretory secretory JJ cord-022526-j9kg00qf 3183 18 response response NN cord-022526-j9kg00qf 3183 19 . . . cord-022526-j9kg00qf 3184 1 Passive passive JJ cord-022526-j9kg00qf 3184 2 secretion secretion NN cord-022526-j9kg00qf 3184 3 of of IN cord-022526-j9kg00qf 3184 4 protein protein NN cord-022526-j9kg00qf 3184 5 - - HYPH cord-022526-j9kg00qf 3184 6 rich rich JJ cord-022526-j9kg00qf 3184 7 fluid fluid NN cord-022526-j9kg00qf 3184 8 into into IN cord-022526-j9kg00qf 3184 9 the the DT cord-022526-j9kg00qf 3184 10 lumen lumen NN cord-022526-j9kg00qf 3184 11 occurs occur VBZ cord-022526-j9kg00qf 3184 12 following follow VBG cord-022526-j9kg00qf 3184 13 damage damage NN cord-022526-j9kg00qf 3184 14 to to IN cord-022526-j9kg00qf 3184 15 the the DT cord-022526-j9kg00qf 3184 16 mucosal mucosal JJ cord-022526-j9kg00qf 3184 17 epithelium epithelium NN cord-022526-j9kg00qf 3184 18 , , , cord-022526-j9kg00qf 3184 19 capillary capillary JJ cord-022526-j9kg00qf 3184 20 endothelium endothelium NN cord-022526-j9kg00qf 3184 21 , , , cord-022526-j9kg00qf 3184 22 and and CC cord-022526-j9kg00qf 3184 23 submucosal submucosal NN cord-022526-j9kg00qf 3184 24 inflammation inflammation NN cord-022526-j9kg00qf 3184 25 in in IN cord-022526-j9kg00qf 3184 26 the the DT cord-022526-j9kg00qf 3184 27 proximal proximal JJ cord-022526-j9kg00qf 3184 28 small small JJ cord-022526-j9kg00qf 3184 29 intestine intestine NN cord-022526-j9kg00qf 3184 30 . . . cord-022526-j9kg00qf 3185 1 The the DT cord-022526-j9kg00qf 3185 2 clinically clinically RB cord-022526-j9kg00qf 3185 3 relevant relevant JJ cord-022526-j9kg00qf 3185 4 events event NNS cord-022526-j9kg00qf 3185 5 that that WDT cord-022526-j9kg00qf 3185 6 result result VBP cord-022526-j9kg00qf 3185 7 from from IN cord-022526-j9kg00qf 3185 8 active active JJ cord-022526-j9kg00qf 3185 9 and and CC cord-022526-j9kg00qf 3185 10 passive passive JJ cord-022526-j9kg00qf 3185 11 fluid fluid JJ cord-022526-j9kg00qf 3185 12 secretion secretion NN cord-022526-j9kg00qf 3185 13 are be VBP cord-022526-j9kg00qf 3185 14 proximal proximal JJ cord-022526-j9kg00qf 3185 15 small small JJ cord-022526-j9kg00qf 3185 16 intestinal intestinal JJ cord-022526-j9kg00qf 3185 17 distention distention NN cord-022526-j9kg00qf 3185 18 and and CC cord-022526-j9kg00qf 3185 19 nasogastric nasogastric NN cord-022526-j9kg00qf 3185 20 reflux reflux NN cord-022526-j9kg00qf 3185 21 , , , cord-022526-j9kg00qf 3185 22 dehydration dehydration NN cord-022526-j9kg00qf 3185 23 , , , cord-022526-j9kg00qf 3185 24 and and CC cord-022526-j9kg00qf 3185 25 circulatory circulatory JJ cord-022526-j9kg00qf 3185 26 shock shock NN cord-022526-j9kg00qf 3185 27 . . . cord-022526-j9kg00qf 3186 1 The the DT cord-022526-j9kg00qf 3186 2 concentration concentration NN cord-022526-j9kg00qf 3186 3 of of IN cord-022526-j9kg00qf 3186 4 protein protein NN cord-022526-j9kg00qf 3186 5 in in IN cord-022526-j9kg00qf 3186 6 the the DT cord-022526-j9kg00qf 3186 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 3186 8 fluid fluid NN cord-022526-j9kg00qf 3186 9 from from IN cord-022526-j9kg00qf 3186 10 horses horse NNS cord-022526-j9kg00qf 3186 11 with with IN cord-022526-j9kg00qf 3186 12 DPJ dpj NN cord-022526-j9kg00qf 3186 13 is be VBZ cord-022526-j9kg00qf 3186 14 usually usually RB cord-022526-j9kg00qf 3186 15 higher high JJR cord-022526-j9kg00qf 3186 16 than than IN cord-022526-j9kg00qf 3186 17 in in IN cord-022526-j9kg00qf 3186 18 horses horse NNS cord-022526-j9kg00qf 3186 19 with with IN cord-022526-j9kg00qf 3186 20 small small JJ cord-022526-j9kg00qf 3186 21 intestinal intestinal JJ cord-022526-j9kg00qf 3186 22 obstruction obstruction NN cord-022526-j9kg00qf 3186 23 . . . cord-022526-j9kg00qf 3187 1 A a DT cord-022526-j9kg00qf 3187 2 disproportionate disproportionate JJ cord-022526-j9kg00qf 3187 3 increase increase NN cord-022526-j9kg00qf 3187 4 in in IN cord-022526-j9kg00qf 3187 5 total total JJ cord-022526-j9kg00qf 3187 6 protein protein NN cord-022526-j9kg00qf 3187 7 concentration concentration NN cord-022526-j9kg00qf 3187 8 relative relative JJ cord-022526-j9kg00qf 3187 9 to to IN cord-022526-j9kg00qf 3187 10 nucleated nucleated JJ cord-022526-j9kg00qf 3187 11 cell cell NN cord-022526-j9kg00qf 3187 12 count count NN cord-022526-j9kg00qf 3187 13 occurs occur VBZ cord-022526-j9kg00qf 3187 14 probably probably RB cord-022526-j9kg00qf 3187 15 by by IN cord-022526-j9kg00qf 3187 16 leakage leakage NN cord-022526-j9kg00qf 3187 17 of of IN cord-022526-j9kg00qf 3187 18 blood blood NN cord-022526-j9kg00qf 3187 19 or or CC cord-022526-j9kg00qf 3187 20 plasma plasma NN cord-022526-j9kg00qf 3187 21 into into IN cord-022526-j9kg00qf 3187 22 the the DT cord-022526-j9kg00qf 3187 23 peritoneal peritoneal JJ cord-022526-j9kg00qf 3187 24 cavity cavity NN cord-022526-j9kg00qf 3187 25 without without IN cord-022526-j9kg00qf 3187 26 a a DT cord-022526-j9kg00qf 3187 27 significant significant JJ cord-022526-j9kg00qf 3187 28 stimulus stimulus NN cord-022526-j9kg00qf 3187 29 for for IN cord-022526-j9kg00qf 3187 30 leukocyte leukocyte NN cord-022526-j9kg00qf 3187 31 chemotaxis chemotaxis NN cord-022526-j9kg00qf 3187 32 . . . cord-022526-j9kg00qf 3188 1 Suggested suggest VBN cord-022526-j9kg00qf 3188 2 mechanisms mechanism NNS cord-022526-j9kg00qf 3188 3 for for IN cord-022526-j9kg00qf 3188 4 increased increase VBN cord-022526-j9kg00qf 3188 5 abdominal abdominal JJ cord-022526-j9kg00qf 3188 6 fluid fluid JJ cord-022526-j9kg00qf 3188 7 protein protein NN cord-022526-j9kg00qf 3188 8 concentration concentration NN cord-022526-j9kg00qf 3188 9 include include VBP cord-022526-j9kg00qf 3188 10 serositis serositis NN cord-022526-j9kg00qf 3188 11 associated associate VBN cord-022526-j9kg00qf 3188 12 with with IN cord-022526-j9kg00qf 3188 13 inflamed inflamed JJ cord-022526-j9kg00qf 3188 14 intestine intestine NN cord-022526-j9kg00qf 3188 15 and and CC cord-022526-j9kg00qf 3188 16 small small JJ cord-022526-j9kg00qf 3188 17 intestinal intestinal JJ cord-022526-j9kg00qf 3188 18 distention distention NN cord-022526-j9kg00qf 3188 19 causing cause VBG cord-022526-j9kg00qf 3188 20 passive passive JJ cord-022526-j9kg00qf 3188 21 congestion congestion NN cord-022526-j9kg00qf 3188 22 and and CC cord-022526-j9kg00qf 3188 23 increased increase VBN cord-022526-j9kg00qf 3188 24 capillary capillary JJ cord-022526-j9kg00qf 3188 25 hydrostatic hydrostatic JJ cord-022526-j9kg00qf 3188 26 pressure pressure NN cord-022526-j9kg00qf 3188 27 of of IN cord-022526-j9kg00qf 3188 28 visceral visceral JJ cord-022526-j9kg00qf 3188 29 peritoneal peritoneal JJ cord-022526-j9kg00qf 3188 30 vessels vessel NNS cord-022526-j9kg00qf 3188 31 . . . cord-022526-j9kg00qf 3189 1 8 8 CD cord-022526-j9kg00qf 3189 2 Small small JJ cord-022526-j9kg00qf 3189 3 intestinal intestinal JJ cord-022526-j9kg00qf 3189 4 ileus ileus NN cord-022526-j9kg00qf 3189 5 is be VBZ cord-022526-j9kg00qf 3189 6 another another DT cord-022526-j9kg00qf 3189 7 hallmark hallmark JJ cord-022526-j9kg00qf 3189 8 sign sign NN cord-022526-j9kg00qf 3189 9 of of IN cord-022526-j9kg00qf 3189 10 DPJ dpj NN cord-022526-j9kg00qf 3189 11 and and CC cord-022526-j9kg00qf 3189 12 the the DT cord-022526-j9kg00qf 3189 13 pathophysiology pathophysiology NN cord-022526-j9kg00qf 3189 14 is be VBZ cord-022526-j9kg00qf 3189 15 complicated complicated JJ cord-022526-j9kg00qf 3189 16 , , , cord-022526-j9kg00qf 3189 17 involving involve VBG cord-022526-j9kg00qf 3189 18 primary primary JJ cord-022526-j9kg00qf 3189 19 and and CC cord-022526-j9kg00qf 3189 20 secondary secondary JJ cord-022526-j9kg00qf 3189 21 dysfunction dysfunction NN cord-022526-j9kg00qf 3189 22 of of IN cord-022526-j9kg00qf 3189 23 the the DT cord-022526-j9kg00qf 3189 24 central central JJ cord-022526-j9kg00qf 3189 25 , , , cord-022526-j9kg00qf 3189 26 autonomic autonomic JJ cord-022526-j9kg00qf 3189 27 , , , cord-022526-j9kg00qf 3189 28 and and CC cord-022526-j9kg00qf 3189 29 enteric enteric JJ cord-022526-j9kg00qf 3189 30 nervous nervous JJ cord-022526-j9kg00qf 3189 31 systems system NNS cord-022526-j9kg00qf 3189 32 and and CC cord-022526-j9kg00qf 3189 33 their -PRON- PRP$ cord-022526-j9kg00qf 3189 34 purported purport VBN cord-022526-j9kg00qf 3189 35 roles role NNS cord-022526-j9kg00qf 3189 36 in in IN cord-022526-j9kg00qf 3189 37 governing govern VBG cord-022526-j9kg00qf 3189 38 intestinal intestinal JJ cord-022526-j9kg00qf 3189 39 motility motility NN cord-022526-j9kg00qf 3189 40 . . . cord-022526-j9kg00qf 3190 1 9 9 CD cord-022526-j9kg00qf 3191 1 Primary primary JJ cord-022526-j9kg00qf 3191 2 role role NN cord-022526-j9kg00qf 3191 3 - - HYPH cord-022526-j9kg00qf 3191 4 players player NNS cord-022526-j9kg00qf 3191 5 in in IN cord-022526-j9kg00qf 3191 6 DPJ dpj NN cord-022526-j9kg00qf 3191 7 - - HYPH cord-022526-j9kg00qf 3191 8 associated associate VBN cord-022526-j9kg00qf 3191 9 ileus ileus NN cord-022526-j9kg00qf 3191 10 include include VBP cord-022526-j9kg00qf 3191 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 3191 12 inflammation inflammation NN cord-022526-j9kg00qf 3191 13 , , , cord-022526-j9kg00qf 3191 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 3191 15 cell cell NN cord-022526-j9kg00qf 3191 16 migration migration NN cord-022526-j9kg00qf 3191 17 / / SYM cord-022526-j9kg00qf 3191 18 activation activation NN cord-022526-j9kg00qf 3191 19 within within IN cord-022526-j9kg00qf 3191 20 the the DT cord-022526-j9kg00qf 3191 21 muscularis muscularis JJ cord-022526-j9kg00qf 3191 22 , , , cord-022526-j9kg00qf 3191 23 small small JJ cord-022526-j9kg00qf 3191 24 intestinal intestinal JJ cord-022526-j9kg00qf 3191 25 mechanical mechanical JJ cord-022526-j9kg00qf 3191 26 distention distention NN cord-022526-j9kg00qf 3191 27 , , , cord-022526-j9kg00qf 3191 28 and and CC cord-022526-j9kg00qf 3191 29 effects effect NNS cord-022526-j9kg00qf 3191 30 of of IN cord-022526-j9kg00qf 3191 31 endotoxin endotoxin NN cord-022526-j9kg00qf 3191 32 absorption absorption NN cord-022526-j9kg00qf 3191 33 . . . cord-022526-j9kg00qf 3192 1 The the DT cord-022526-j9kg00qf 3192 2 use use NN cord-022526-j9kg00qf 3192 3 of of IN cord-022526-j9kg00qf 3192 4 prokinetic prokinetic JJ cord-022526-j9kg00qf 3192 5 agents agent NNS cord-022526-j9kg00qf 3192 6 for for IN cord-022526-j9kg00qf 3192 7 treating treat VBG cord-022526-j9kg00qf 3192 8 ileus ileus NN cord-022526-j9kg00qf 3192 9 and and CC cord-022526-j9kg00qf 3192 10 gastric gastric JJ cord-022526-j9kg00qf 3192 11 / / SYM cord-022526-j9kg00qf 3192 12 small small JJ cord-022526-j9kg00qf 3192 13 intestinal intestinal JJ cord-022526-j9kg00qf 3192 14 distention distention NN cord-022526-j9kg00qf 3192 15 in in IN cord-022526-j9kg00qf 3192 16 horses horse NNS cord-022526-j9kg00qf 3192 17 with with IN cord-022526-j9kg00qf 3192 18 DPJ dpj NN cord-022526-j9kg00qf 3192 19 is be VBZ cord-022526-j9kg00qf 3192 20 becoming become VBG cord-022526-j9kg00qf 3192 21 more more RBR cord-022526-j9kg00qf 3192 22 common common JJ cord-022526-j9kg00qf 3192 23 , , , cord-022526-j9kg00qf 3192 24 but but CC cord-022526-j9kg00qf 3192 25 veterinarians veterinarian NNS cord-022526-j9kg00qf 3192 26 should should MD cord-022526-j9kg00qf 3192 27 realize realize VB cord-022526-j9kg00qf 3192 28 that that IN cord-022526-j9kg00qf 3192 29 a a DT cord-022526-j9kg00qf 3192 30 potential potential JJ cord-022526-j9kg00qf 3192 31 restriction restriction NN cord-022526-j9kg00qf 3192 32 on on IN cord-022526-j9kg00qf 3192 33 their -PRON- PRP$ cord-022526-j9kg00qf 3192 34 use use NN cord-022526-j9kg00qf 3192 35 is be VBZ cord-022526-j9kg00qf 3192 36 the the DT cord-022526-j9kg00qf 3192 37 need need NN cord-022526-j9kg00qf 3192 38 for for IN cord-022526-j9kg00qf 3192 39 normal normal JJ cord-022526-j9kg00qf 3192 40 intestinal intestinal JJ cord-022526-j9kg00qf 3192 41 integrity integrity NN cord-022526-j9kg00qf 3192 42 . . . cord-022526-j9kg00qf 3193 1 In in IN cord-022526-j9kg00qf 3193 2 spite spite NN cord-022526-j9kg00qf 3193 3 of of IN cord-022526-j9kg00qf 3193 4 that that DT cord-022526-j9kg00qf 3193 5 , , , cord-022526-j9kg00qf 3193 6 one one PRP cord-022526-j9kg00qf 3193 7 may may MD cord-022526-j9kg00qf 3193 8 use use VB cord-022526-j9kg00qf 3193 9 motility motility NN cord-022526-j9kg00qf 3193 10 modifiers modifier NNS cord-022526-j9kg00qf 3193 11 judiciously judiciously RB cord-022526-j9kg00qf 3193 12 . . . cord-022526-j9kg00qf 3194 1 The the DT cord-022526-j9kg00qf 3194 2 veterinarian veterinarian NN cord-022526-j9kg00qf 3194 3 has have VBZ cord-022526-j9kg00qf 3194 4 the the DT cord-022526-j9kg00qf 3194 5 challenge challenge NN cord-022526-j9kg00qf 3194 6 of of IN cord-022526-j9kg00qf 3194 7 differentiating differentiate VBG cord-022526-j9kg00qf 3194 8 horses horse NNS cord-022526-j9kg00qf 3194 9 with with IN cord-022526-j9kg00qf 3194 10 DPJ dpj NN cord-022526-j9kg00qf 3194 11 from from IN cord-022526-j9kg00qf 3194 12 horses horse NNS cord-022526-j9kg00qf 3194 13 with with IN cord-022526-j9kg00qf 3194 14 small small JJ cord-022526-j9kg00qf 3194 15 intestinal intestinal JJ cord-022526-j9kg00qf 3194 16 obstructive obstructive JJ cord-022526-j9kg00qf 3194 17 lesions lesion NNS cord-022526-j9kg00qf 3194 18 so so IN cord-022526-j9kg00qf 3194 19 as as IN cord-022526-j9kg00qf 3194 20 to to TO cord-022526-j9kg00qf 3194 21 avoid avoid VB cord-022526-j9kg00qf 3194 22 surgical surgical JJ cord-022526-j9kg00qf 3194 23 intervention intervention NN cord-022526-j9kg00qf 3194 24 ( ( -LRB- cord-022526-j9kg00qf 3194 25 Table Table NNP cord-022526-j9kg00qf 3194 26 13 13 CD cord-022526-j9kg00qf 3194 27 .11 .11 CD cord-022526-j9kg00qf 3194 28 - - SYM cord-022526-j9kg00qf 3194 29 1 1 CD cord-022526-j9kg00qf 3194 30 ) ) -RRB- cord-022526-j9kg00qf 3194 31 . . . cord-022526-j9kg00qf 3195 1 Horses horse NNS cord-022526-j9kg00qf 3195 2 with with IN cord-022526-j9kg00qf 3195 3 DPJ dpj NN cord-022526-j9kg00qf 3195 4 typically typically RB cord-022526-j9kg00qf 3195 5 show show VBP cord-022526-j9kg00qf 3195 6 signs sign NNS cord-022526-j9kg00qf 3195 7 of of IN cord-022526-j9kg00qf 3195 8 acute acute JJ cord-022526-j9kg00qf 3195 9 abdominal abdominal JJ cord-022526-j9kg00qf 3195 10 pain pain NN cord-022526-j9kg00qf 3195 11 initially initially RB cord-022526-j9kg00qf 3195 12 , , , cord-022526-j9kg00qf 3195 13 and and CC cord-022526-j9kg00qf 3195 14 then then RB cord-022526-j9kg00qf 3195 15 after after IN cord-022526-j9kg00qf 3195 16 gastric gastric JJ cord-022526-j9kg00qf 3195 17 decompression decompression NN cord-022526-j9kg00qf 3195 18 , , , cord-022526-j9kg00qf 3195 19 volume volume NN cord-022526-j9kg00qf 3195 20 replacement replacement NN cord-022526-j9kg00qf 3195 21 , , , cord-022526-j9kg00qf 3195 22 and and CC cord-022526-j9kg00qf 3195 23 analgesic analgesic JJ cord-022526-j9kg00qf 3195 24 therapy therapy NN cord-022526-j9kg00qf 3195 25 , , , cord-022526-j9kg00qf 3195 26 the the DT cord-022526-j9kg00qf 3195 27 colic colic NN cord-022526-j9kg00qf 3195 28 signs sign NNS cord-022526-j9kg00qf 3195 29 subside subside VBP cord-022526-j9kg00qf 3195 30 , , , cord-022526-j9kg00qf 3195 31 but but CC cord-022526-j9kg00qf 3195 32 signs sign NNS cord-022526-j9kg00qf 3195 33 of of IN cord-022526-j9kg00qf 3195 34 lethargy lethargy NN cord-022526-j9kg00qf 3195 35 and and CC cord-022526-j9kg00qf 3195 36 malaise malaise NN cord-022526-j9kg00qf 3195 37 become become VBP cord-022526-j9kg00qf 3195 38 more more RBR cord-022526-j9kg00qf 3195 39 apparent apparent JJ cord-022526-j9kg00qf 3195 40 . . . cord-022526-j9kg00qf 3196 1 In in IN cord-022526-j9kg00qf 3196 2 contrast contrast NN cord-022526-j9kg00qf 3196 3 , , , cord-022526-j9kg00qf 3196 4 horses horse NNS cord-022526-j9kg00qf 3196 5 with with IN cord-022526-j9kg00qf 3196 6 obstructive obstructive JJ cord-022526-j9kg00qf 3196 7 lesions lesion NNS cord-022526-j9kg00qf 3196 8 of of IN cord-022526-j9kg00qf 3196 9 the the DT cord-022526-j9kg00qf 3196 10 small small JJ cord-022526-j9kg00qf 3196 11 intestine intestine NN cord-022526-j9kg00qf 3196 12 usually usually RB cord-022526-j9kg00qf 3196 13 show show VBP cord-022526-j9kg00qf 3196 14 signs sign NNS cord-022526-j9kg00qf 3196 15 of of IN cord-022526-j9kg00qf 3196 16 abdominal abdominal JJ cord-022526-j9kg00qf 3196 17 pain pain NN cord-022526-j9kg00qf 3196 18 until until IN cord-022526-j9kg00qf 3196 19 the the DT cord-022526-j9kg00qf 3196 20 affected affected JJ cord-022526-j9kg00qf 3196 21 viscus viscus NN cord-022526-j9kg00qf 3196 22 is be VBZ cord-022526-j9kg00qf 3196 23 repaired repair VBN cord-022526-j9kg00qf 3196 24 via via IN cord-022526-j9kg00qf 3196 25 surgical surgical JJ cord-022526-j9kg00qf 3196 26 intervention intervention NN cord-022526-j9kg00qf 3196 27 or or CC cord-022526-j9kg00qf 3196 28 the the DT cord-022526-j9kg00qf 3196 29 viscus viscus NN cord-022526-j9kg00qf 3196 30 ruptures rupture NNS cord-022526-j9kg00qf 3196 31 . . . cord-022526-j9kg00qf 3197 1 Another another DT cord-022526-j9kg00qf 3197 2 differentiating differentiate VBG cord-022526-j9kg00qf 3197 3 characteristic characteristic NN cord-022526-j9kg00qf 3197 4 is be VBZ cord-022526-j9kg00qf 3197 5 the the DT cord-022526-j9kg00qf 3197 6 large large JJ cord-022526-j9kg00qf 3197 7 volume volume NN cord-022526-j9kg00qf 3197 8 ( ( -LRB- cord-022526-j9kg00qf 3197 9 > > XX cord-022526-j9kg00qf 3197 10 4 4 CD cord-022526-j9kg00qf 3197 11 to to TO cord-022526-j9kg00qf 3197 12 20 20 CD cord-022526-j9kg00qf 3197 13 L l NN cord-022526-j9kg00qf 3197 14 with with IN cord-022526-j9kg00qf 3197 15 each each DT cord-022526-j9kg00qf 3197 16 decompressive decompressive JJ cord-022526-j9kg00qf 3197 17 effort effort NN cord-022526-j9kg00qf 3197 18 ) ) -RRB- cord-022526-j9kg00qf 3197 19 of of IN cord-022526-j9kg00qf 3197 20 nasogastric nasogastric NN cord-022526-j9kg00qf 3197 21 reflux reflux NN cord-022526-j9kg00qf 3197 22 that that WDT cord-022526-j9kg00qf 3197 23 is be VBZ cord-022526-j9kg00qf 3197 24 often often RB cord-022526-j9kg00qf 3197 25 malodorous malodorous JJ cord-022526-j9kg00qf 3197 26 and and CC cord-022526-j9kg00qf 3197 27 orange orange JJ cord-022526-j9kg00qf 3197 28 - - HYPH cord-022526-j9kg00qf 3197 29 brown brown JJ cord-022526-j9kg00qf 3197 30 or or CC cord-022526-j9kg00qf 3197 31 red red JJ cord-022526-j9kg00qf 3197 32 - - HYPH cord-022526-j9kg00qf 3197 33 brown brown JJ cord-022526-j9kg00qf 3197 34 . . . cord-022526-j9kg00qf 3198 1 DPJ dpj NN cord-022526-j9kg00qf 3198 2 - - HYPH cord-022526-j9kg00qf 3198 3 affected affect VBN cord-022526-j9kg00qf 3198 4 horses horse NNS cord-022526-j9kg00qf 3198 5 have have VBP cord-022526-j9kg00qf 3198 6 moderate moderate JJ cord-022526-j9kg00qf 3198 7 to to TO cord-022526-j9kg00qf 3198 8 severe severe JJ cord-022526-j9kg00qf 3198 9 small small JJ cord-022526-j9kg00qf 3198 10 intestinal intestinal JJ cord-022526-j9kg00qf 3198 11 distention distention NN cord-022526-j9kg00qf 3198 12 palpated palpate VBN cord-022526-j9kg00qf 3198 13 on on IN cord-022526-j9kg00qf 3198 14 rectal rectal JJ cord-022526-j9kg00qf 3198 15 examination examination NN cord-022526-j9kg00qf 3198 16 , , , cord-022526-j9kg00qf 3198 17 temperature temperature NN cord-022526-j9kg00qf 3198 18 of of IN cord-022526-j9kg00qf 3198 19 38.6 38.6 CD cord-022526-j9kg00qf 3198 20 ° ° NNS cord-022526-j9kg00qf 3198 21 to to IN cord-022526-j9kg00qf 3198 22 39.1 39.1 CD cord-022526-j9kg00qf 3198 23 ° ° NN cord-022526-j9kg00qf 3198 24 C c NN cord-022526-j9kg00qf 3198 25 ( ( -LRB- cord-022526-j9kg00qf 3198 26 101.5 101.5 CD cord-022526-j9kg00qf 3198 27 ° ° NN cord-022526-j9kg00qf 3198 28 to to IN cord-022526-j9kg00qf 3198 29 102.5 102.5 CD cord-022526-j9kg00qf 3198 30 ° ° NN cord-022526-j9kg00qf 3198 31 F F NNP cord-022526-j9kg00qf 3198 32 ) ) -RRB- cord-022526-j9kg00qf 3198 33 , , , cord-022526-j9kg00qf 3198 34 dehydration dehydration NN cord-022526-j9kg00qf 3198 35 , , , cord-022526-j9kg00qf 3198 36 brick brick NN cord-022526-j9kg00qf 3198 37 - - HYPH cord-022526-j9kg00qf 3198 38 red red JJ cord-022526-j9kg00qf 3198 39 mucous mucous JJ cord-022526-j9kg00qf 3198 40 membranes membrane NNS cord-022526-j9kg00qf 3198 41 , , , cord-022526-j9kg00qf 3198 42 lethargy lethargy NN cord-022526-j9kg00qf 3198 43 and and CC cord-022526-j9kg00qf 3198 44 absent absent JJ cord-022526-j9kg00qf 3198 45 borborygmi borborygmi NN cord-022526-j9kg00qf 3198 46 , , , cord-022526-j9kg00qf 3198 47 prolonged prolonged JJ cord-022526-j9kg00qf 3198 48 capillary capillary JJ cord-022526-j9kg00qf 3198 49 refill refill NN cord-022526-j9kg00qf 3198 50 time time NN cord-022526-j9kg00qf 3198 51 , , , cord-022526-j9kg00qf 3198 52 tachycardia tachycardia NN cord-022526-j9kg00qf 3198 53 ( ( -LRB- cord-022526-j9kg00qf 3198 54 > > SYM cord-022526-j9kg00qf 3198 55 60 60 CD cord-022526-j9kg00qf 3198 56 beats beat NNS cord-022526-j9kg00qf 3198 57 / / SYM cord-022526-j9kg00qf 3198 58 min min NNP cord-022526-j9kg00qf 3198 59 ) ) -RRB- cord-022526-j9kg00qf 3198 60 , , , cord-022526-j9kg00qf 3198 61 and and CC cord-022526-j9kg00qf 3198 62 tachypnea tachypnea NNP cord-022526-j9kg00qf 3198 63 . . . cord-022526-j9kg00qf 3199 1 Although although IN cord-022526-j9kg00qf 3199 2 the the DT cord-022526-j9kg00qf 3199 3 signs sign NNS cord-022526-j9kg00qf 3199 4 of of IN cord-022526-j9kg00qf 3199 5 abdominal abdominal JJ cord-022526-j9kg00qf 3199 6 pain pain NN cord-022526-j9kg00qf 3199 7 usually usually RB cord-022526-j9kg00qf 3199 8 resolve resolve VBP cord-022526-j9kg00qf 3199 9 after after IN cord-022526-j9kg00qf 3199 10 gastric gastric JJ cord-022526-j9kg00qf 3199 11 decompression decompression NN cord-022526-j9kg00qf 3199 12 , , , cord-022526-j9kg00qf 3199 13 most most JJS cord-022526-j9kg00qf 3199 14 horses horse NNS cord-022526-j9kg00qf 3199 15 remain remain VBP cord-022526-j9kg00qf 3199 16 severely severely RB cord-022526-j9kg00qf 3199 17 lethargic lethargic JJ cord-022526-j9kg00qf 3199 18 . . . cord-022526-j9kg00qf 3200 1 Without without IN cord-022526-j9kg00qf 3200 2 periodic periodic JJ cord-022526-j9kg00qf 3200 3 removal removal NN cord-022526-j9kg00qf 3200 4 of of IN cord-022526-j9kg00qf 3200 5 the the DT cord-022526-j9kg00qf 3200 6 fluid fluid NN cord-022526-j9kg00qf 3200 7 that that WDT cord-022526-j9kg00qf 3200 8 accumulates accumulate VBZ cord-022526-j9kg00qf 3200 9 in in IN cord-022526-j9kg00qf 3200 10 the the DT cord-022526-j9kg00qf 3200 11 proximal proximal JJ cord-022526-j9kg00qf 3200 12 intestinal intestinal JJ cord-022526-j9kg00qf 3200 13 tract tract NN cord-022526-j9kg00qf 3200 14 , , , cord-022526-j9kg00qf 3200 15 signs sign NNS cord-022526-j9kg00qf 3200 16 of of IN cord-022526-j9kg00qf 3200 17 abdominal abdominal JJ cord-022526-j9kg00qf 3200 18 pain pain NN cord-022526-j9kg00qf 3200 19 usually usually RB cord-022526-j9kg00qf 3200 20 recur recur VBP cord-022526-j9kg00qf 3200 21 . . . cord-022526-j9kg00qf 3201 1 Horses horse NNS cord-022526-j9kg00qf 3201 2 with with IN cord-022526-j9kg00qf 3201 3 DPJ dpj NN cord-022526-j9kg00qf 3201 4 often often RB cord-022526-j9kg00qf 3201 5 require require VBP cord-022526-j9kg00qf 3201 6 gastric gastric JJ cord-022526-j9kg00qf 3201 7 decompression decompression NN cord-022526-j9kg00qf 3201 8 at at IN cord-022526-j9kg00qf 3201 9 2-hour 2-hour CD cord-022526-j9kg00qf 3201 10 intervals interval NNS cord-022526-j9kg00qf 3201 11 , , , cord-022526-j9kg00qf 3201 12 with with IN cord-022526-j9kg00qf 3201 13 2 2 CD cord-022526-j9kg00qf 3201 14 to to TO cord-022526-j9kg00qf 3201 15 10 10 CD cord-022526-j9kg00qf 3201 16 L l NN cord-022526-j9kg00qf 3201 17 of of IN cord-022526-j9kg00qf 3201 18 fluid fluid NN cord-022526-j9kg00qf 3201 19 recovered recover VBD cord-022526-j9kg00qf 3201 20 each each DT cord-022526-j9kg00qf 3201 21 time time NN cord-022526-j9kg00qf 3201 22 . . . cord-022526-j9kg00qf 3202 1 Nasogastric nasogastric NN cord-022526-j9kg00qf 3202 2 tubes tube NNS cord-022526-j9kg00qf 3202 3 left leave VBN cord-022526-j9kg00qf 3202 4 in in IN cord-022526-j9kg00qf 3202 5 place place NN cord-022526-j9kg00qf 3202 6 for for IN cord-022526-j9kg00qf 3202 7 long long JJ cord-022526-j9kg00qf 3202 8 periods period NNS cord-022526-j9kg00qf 3202 9 of of IN cord-022526-j9kg00qf 3202 10 time time NN cord-022526-j9kg00qf 3202 11 cause cause NN cord-022526-j9kg00qf 3202 12 varying vary VBG cord-022526-j9kg00qf 3202 13 degrees degree NNS cord-022526-j9kg00qf 3202 14 of of IN cord-022526-j9kg00qf 3202 15 pharyngitis pharyngitis NN cord-022526-j9kg00qf 3202 16 , , , cord-022526-j9kg00qf 3202 17 laryngitis laryngitis NN cord-022526-j9kg00qf 3202 18 , , , cord-022526-j9kg00qf 3202 19 and and CC cord-022526-j9kg00qf 3202 20 esophagitis esophagitis NN cord-022526-j9kg00qf 3202 21 . . . cord-022526-j9kg00qf 3203 1 Typical typical JJ cord-022526-j9kg00qf 3203 2 clinical clinical JJ cord-022526-j9kg00qf 3203 3 laboratory laboratory NN cord-022526-j9kg00qf 3203 4 findings finding NNS cord-022526-j9kg00qf 3203 5 include include VBP cord-022526-j9kg00qf 3203 6 an an DT cord-022526-j9kg00qf 3203 7 increased increase VBN cord-022526-j9kg00qf 3203 8 packed packed JJ cord-022526-j9kg00qf 3203 9 cell cell NN cord-022526-j9kg00qf 3203 10 volume volume NN cord-022526-j9kg00qf 3203 11 and and CC cord-022526-j9kg00qf 3203 12 total total JJ cord-022526-j9kg00qf 3203 13 plasma plasma NN cord-022526-j9kg00qf 3203 14 protein protein NN cord-022526-j9kg00qf 3203 15 reflective reflective JJ cord-022526-j9kg00qf 3203 16 of of IN cord-022526-j9kg00qf 3203 17 volume volume NN cord-022526-j9kg00qf 3203 18 depletion depletion NN cord-022526-j9kg00qf 3203 19 , , , cord-022526-j9kg00qf 3203 20 a a DT cord-022526-j9kg00qf 3203 21 metabolic metabolic JJ cord-022526-j9kg00qf 3203 22 acidosis acidosis NN cord-022526-j9kg00qf 3203 23 ( ( -LRB- cord-022526-j9kg00qf 3203 24 with with IN cord-022526-j9kg00qf 3203 25 elevated elevated JJ cord-022526-j9kg00qf 3203 26 anion anion NN cord-022526-j9kg00qf 3203 27 gap gap NN cord-022526-j9kg00qf 3203 28 ) ) -RRB- cord-022526-j9kg00qf 3203 29 in in IN cord-022526-j9kg00qf 3203 30 longstanding longstanding JJ cord-022526-j9kg00qf 3203 31 or or CC cord-022526-j9kg00qf 3203 32 severe severe JJ cord-022526-j9kg00qf 3203 33 cases case NNS cord-022526-j9kg00qf 3203 34 , , , cord-022526-j9kg00qf 3203 35 an an DT cord-022526-j9kg00qf 3203 36 increased increase VBN cord-022526-j9kg00qf 3203 37 peritoneal peritoneal JJ cord-022526-j9kg00qf 3203 38 fluid fluid NN cord-022526-j9kg00qf 3203 39 protein protein NN cord-022526-j9kg00qf 3203 40 concentration concentration NN cord-022526-j9kg00qf 3203 41 ( ( -LRB- cord-022526-j9kg00qf 3203 42 often often RB cord-022526-j9kg00qf 3203 43 > > XX cord-022526-j9kg00qf 3203 44 3.5 3.5 CD cord-022526-j9kg00qf 3203 45 g g NN cord-022526-j9kg00qf 3203 46 / / SYM cord-022526-j9kg00qf 3203 47 dl dl NNP cord-022526-j9kg00qf 3203 48 ) ) -RRB- cord-022526-j9kg00qf 3203 49 , , , cord-022526-j9kg00qf 3203 50 and and CC cord-022526-j9kg00qf 3203 51 a a DT cord-022526-j9kg00qf 3203 52 mild mild JJ cord-022526-j9kg00qf 3203 53 to to IN cord-022526-j9kg00qf 3203 54 moderate moderate JJ cord-022526-j9kg00qf 3203 55 elevation elevation NN cord-022526-j9kg00qf 3203 56 of of IN cord-022526-j9kg00qf 3203 57 the the DT cord-022526-j9kg00qf 3203 58 peritoneal peritoneal JJ cord-022526-j9kg00qf 3203 59 white white JJ cord-022526-j9kg00qf 3203 60 blood blood NN cord-022526-j9kg00qf 3203 61 cell cell NN cord-022526-j9kg00qf 3203 62 count count NN cord-022526-j9kg00qf 3203 63 , , , cord-022526-j9kg00qf 3203 64 although although IN cord-022526-j9kg00qf 3203 65 the the DT cord-022526-j9kg00qf 3203 66 count count NN cord-022526-j9kg00qf 3203 67 usually usually RB cord-022526-j9kg00qf 3203 68 is be VBZ cord-022526-j9kg00qf 3203 69 less less JJR cord-022526-j9kg00qf 3203 70 than than IN cord-022526-j9kg00qf 3203 71 10,000 10,000 CD cord-022526-j9kg00qf 3203 72 cells cell NNS cord-022526-j9kg00qf 3203 73 per per IN cord-022526-j9kg00qf 3203 74 microliter microliter NN cord-022526-j9kg00qf 3203 75 . . . cord-022526-j9kg00qf 3204 1 3 3 LS cord-022526-j9kg00qf 3204 2 , , , cord-022526-j9kg00qf 3204 3 4 4 CD cord-022526-j9kg00qf 3204 4 The the DT cord-022526-j9kg00qf 3204 5 peritoneal peritoneal JJ cord-022526-j9kg00qf 3204 6 fluid fluid NN cord-022526-j9kg00qf 3204 7 is be VBZ cord-022526-j9kg00qf 3204 8 usually usually RB cord-022526-j9kg00qf 3204 9 yellow yellow JJ cord-022526-j9kg00qf 3204 10 and and CC cord-022526-j9kg00qf 3204 11 turbid turbid JJ cord-022526-j9kg00qf 3204 12 , , , cord-022526-j9kg00qf 3204 13 but but CC cord-022526-j9kg00qf 3204 14 in in IN cord-022526-j9kg00qf 3204 15 severe severe JJ cord-022526-j9kg00qf 3204 16 cases case NNS cord-022526-j9kg00qf 3204 17 diapedesis diapedesis NN cord-022526-j9kg00qf 3204 18 occurs occur VBZ cord-022526-j9kg00qf 3204 19 resulting result VBG cord-022526-j9kg00qf 3204 20 in in IN cord-022526-j9kg00qf 3204 21 a a DT cord-022526-j9kg00qf 3204 22 serosanguinous serosanguinous JJ cord-022526-j9kg00qf 3204 23 color color NN cord-022526-j9kg00qf 3204 24 . . . cord-022526-j9kg00qf 3205 1 The the DT cord-022526-j9kg00qf 3205 2 white white JJ cord-022526-j9kg00qf 3205 3 blood blood NN cord-022526-j9kg00qf 3205 4 cell cell NN cord-022526-j9kg00qf 3205 5 count count NN cord-022526-j9kg00qf 3205 6 in in IN cord-022526-j9kg00qf 3205 7 the the DT cord-022526-j9kg00qf 3205 8 peripheral peripheral JJ cord-022526-j9kg00qf 3205 9 blood blood NN cord-022526-j9kg00qf 3205 10 may may MD cord-022526-j9kg00qf 3205 11 be be VB cord-022526-j9kg00qf 3205 12 normal normal JJ cord-022526-j9kg00qf 3205 13 , , , cord-022526-j9kg00qf 3205 14 decreased decrease VBD cord-022526-j9kg00qf 3205 15 , , , cord-022526-j9kg00qf 3205 16 or or CC cord-022526-j9kg00qf 3205 17 increased increase VBD cord-022526-j9kg00qf 3205 18 . . . cord-022526-j9kg00qf 3206 1 In in IN cord-022526-j9kg00qf 3206 2 addition addition NN cord-022526-j9kg00qf 3206 3 , , , cord-022526-j9kg00qf 3206 4 hyponatremia hyponatremia NN cord-022526-j9kg00qf 3206 5 , , , cord-022526-j9kg00qf 3206 6 hypochloremia hypochloremia NN cord-022526-j9kg00qf 3206 7 , , , cord-022526-j9kg00qf 3206 8 hypokalemia hypokalemia NN cord-022526-j9kg00qf 3206 9 , , , cord-022526-j9kg00qf 3206 10 and and CC cord-022526-j9kg00qf 3206 11 acid acid NN cord-022526-j9kg00qf 3206 12 - - HYPH cord-022526-j9kg00qf 3206 13 base base NN cord-022526-j9kg00qf 3206 14 alterations alteration NNS cord-022526-j9kg00qf 3206 15 ( ( -LRB- cord-022526-j9kg00qf 3206 16 elevated elevated JJ cord-022526-j9kg00qf 3206 17 anion anion NN cord-022526-j9kg00qf 3206 18 gap gap NN cord-022526-j9kg00qf 3206 19 ) ) -RRB- cord-022526-j9kg00qf 3206 20 are be VBP cord-022526-j9kg00qf 3206 21 often often RB cord-022526-j9kg00qf 3206 22 evident evident JJ cord-022526-j9kg00qf 3206 23 . . . cord-022526-j9kg00qf 3207 1 The the DT cord-022526-j9kg00qf 3207 2 loss loss NN cord-022526-j9kg00qf 3207 3 of of IN cord-022526-j9kg00qf 3207 4 enteric enteric JJ cord-022526-j9kg00qf 3207 5 bicarbonate bicarbonate NN cord-022526-j9kg00qf 3207 6 through through IN cord-022526-j9kg00qf 3207 7 evacuation evacuation NN cord-022526-j9kg00qf 3207 8 of of IN cord-022526-j9kg00qf 3207 9 enterogastric enterogastric JJ cord-022526-j9kg00qf 3207 10 reflux reflux NN cord-022526-j9kg00qf 3207 11 and and CC cord-022526-j9kg00qf 3207 12 poor poor JJ cord-022526-j9kg00qf 3207 13 tissue tissue NN cord-022526-j9kg00qf 3207 14 perfusion perfusion NN cord-022526-j9kg00qf 3207 15 from from IN cord-022526-j9kg00qf 3207 16 hypovolemia hypovolemia NN cord-022526-j9kg00qf 3207 17 can can MD cord-022526-j9kg00qf 3207 18 lead lead VB cord-022526-j9kg00qf 3207 19 to to IN cord-022526-j9kg00qf 3207 20 metabolic metabolic JJ cord-022526-j9kg00qf 3207 21 acidosis acidosis NN cord-022526-j9kg00qf 3207 22 . . . cord-022526-j9kg00qf 3208 1 One one PRP cord-022526-j9kg00qf 3208 2 makes make VBZ cord-022526-j9kg00qf 3208 3 a a DT cord-022526-j9kg00qf 3208 4 definitive definitive JJ cord-022526-j9kg00qf 3208 5 diagnosis diagnosis NN cord-022526-j9kg00qf 3208 6 of of IN cord-022526-j9kg00qf 3208 7 DPJ dpj NN cord-022526-j9kg00qf 3208 8 in in IN cord-022526-j9kg00qf 3208 9 most most JJS cord-022526-j9kg00qf 3208 10 cases case NNS cord-022526-j9kg00qf 3208 11 by by IN cord-022526-j9kg00qf 3208 12 gross gross JJ cord-022526-j9kg00qf 3208 13 examination examination NN cord-022526-j9kg00qf 3208 14 of of IN cord-022526-j9kg00qf 3208 15 the the DT cord-022526-j9kg00qf 3208 16 duodenum duodenum NN cord-022526-j9kg00qf 3208 17 and and CC cord-022526-j9kg00qf 3208 18 proximal proximal JJ cord-022526-j9kg00qf 3208 19 jejunum jejunum NNS cord-022526-j9kg00qf 3208 20 at at IN cord-022526-j9kg00qf 3208 21 surgery surgery NN cord-022526-j9kg00qf 3208 22 or or CC cord-022526-j9kg00qf 3208 23 at at IN cord-022526-j9kg00qf 3208 24 necropsy necropsy JJ cord-022526-j9kg00qf 3208 25 . . . cord-022526-j9kg00qf 3209 1 Some some DT cord-022526-j9kg00qf 3209 2 equine equine JJ cord-022526-j9kg00qf 3209 3 practitioners practitioner NNS cord-022526-j9kg00qf 3209 4 have have VBP cord-022526-j9kg00qf 3209 5 observed observe VBN cord-022526-j9kg00qf 3209 6 an an DT cord-022526-j9kg00qf 3209 7 apparent apparent JJ cord-022526-j9kg00qf 3209 8 geographic geographic JJ cord-022526-j9kg00qf 3209 9 relationship relationship NN cord-022526-j9kg00qf 3209 10 in in IN cord-022526-j9kg00qf 3209 11 the the DT cord-022526-j9kg00qf 3209 12 incidence incidence NN cord-022526-j9kg00qf 3209 13 and and CC cord-022526-j9kg00qf 3209 14 severity severity NN cord-022526-j9kg00qf 3209 15 of of IN cord-022526-j9kg00qf 3209 16 the the DT cord-022526-j9kg00qf 3209 17 syndrome syndrome NN cord-022526-j9kg00qf 3209 18 , , , cord-022526-j9kg00qf 3209 19 with with IN cord-022526-j9kg00qf 3209 20 more more JJR cord-022526-j9kg00qf 3209 21 cases case NNS cord-022526-j9kg00qf 3209 22 occurring occur VBG cord-022526-j9kg00qf 3209 23 in in IN cord-022526-j9kg00qf 3209 24 the the DT cord-022526-j9kg00qf 3209 25 southeastern southeastern JJ cord-022526-j9kg00qf 3209 26 United United NNP cord-022526-j9kg00qf 3209 27 States States NNP cord-022526-j9kg00qf 3209 28 . . . cord-022526-j9kg00qf 3210 1 Horses horse NNS cord-022526-j9kg00qf 3210 2 with with IN cord-022526-j9kg00qf 3210 3 DPJ dpj NN cord-022526-j9kg00qf 3210 4 appear appear VBP cord-022526-j9kg00qf 3210 5 to to TO cord-022526-j9kg00qf 3210 6 share share VB cord-022526-j9kg00qf 3210 7 a a DT cord-022526-j9kg00qf 3210 8 common common JJ cord-022526-j9kg00qf 3210 9 characteristic characteristic JJ cord-022526-j9kg00qf 3210 10 clinical clinical JJ cord-022526-j9kg00qf 3210 11 presentation presentation NN cord-022526-j9kg00qf 3210 12 , , , cord-022526-j9kg00qf 3210 13 and and CC cord-022526-j9kg00qf 3210 14 the the DT cord-022526-j9kg00qf 3210 15 mechanisms mechanism NNS cord-022526-j9kg00qf 3210 16 leading lead VBG cord-022526-j9kg00qf 3210 17 to to IN cord-022526-j9kg00qf 3210 18 electrolyte electrolyte JJ cord-022526-j9kg00qf 3210 19 imbalances imbalance NNS cord-022526-j9kg00qf 3210 20 , , , cord-022526-j9kg00qf 3210 21 fluid fluid JJ cord-022526-j9kg00qf 3210 22 loss loss NN cord-022526-j9kg00qf 3210 23 , , , cord-022526-j9kg00qf 3210 24 ileus ileus NN cord-022526-j9kg00qf 3210 25 , , , cord-022526-j9kg00qf 3210 26 and and CC cord-022526-j9kg00qf 3210 27 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3210 28 and and CC cord-022526-j9kg00qf 3210 29 septicemia septicemia NN cord-022526-j9kg00qf 3210 30 are be VBP cord-022526-j9kg00qf 3210 31 similar similar JJ cord-022526-j9kg00qf 3210 32 . . . cord-022526-j9kg00qf 3211 1 Treatment treatment NN cord-022526-j9kg00qf 3211 2 regimens regimen NNS cord-022526-j9kg00qf 3211 3 are be VBP cord-022526-j9kg00qf 3211 4 supportive supportive JJ cord-022526-j9kg00qf 3211 5 and and CC cord-022526-j9kg00qf 3211 6 aim aim VB cord-022526-j9kg00qf 3211 7 at at IN cord-022526-j9kg00qf 3211 8 plasma plasma NN cord-022526-j9kg00qf 3211 9 volume volume NN cord-022526-j9kg00qf 3211 10 replacement replacement NN cord-022526-j9kg00qf 3211 11 ( ( -LRB- cord-022526-j9kg00qf 3211 12 usually usually RB cord-022526-j9kg00qf 3211 13 in in IN cord-022526-j9kg00qf 3211 14 the the DT cord-022526-j9kg00qf 3211 15 form form NN cord-022526-j9kg00qf 3211 16 of of IN cord-022526-j9kg00qf 3211 17 crystalloid crystalloid NN cord-022526-j9kg00qf 3211 18 fluid fluid JJ cord-022526-j9kg00qf 3211 19 replacement replacement NN cord-022526-j9kg00qf 3211 20 ) ) -RRB- cord-022526-j9kg00qf 3211 21 , , , cord-022526-j9kg00qf 3211 22 analgesia analgesia NN cord-022526-j9kg00qf 3211 23 and and CC cord-022526-j9kg00qf 3211 24 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3211 25 therapy therapy NN cord-022526-j9kg00qf 3211 26 , , , cord-022526-j9kg00qf 3211 27 gastric gastric JJ cord-022526-j9kg00qf 3211 28 decompression decompression NN cord-022526-j9kg00qf 3211 29 , , , cord-022526-j9kg00qf 3211 30 antiendotoxin antiendotoxin NNP cord-022526-j9kg00qf 3211 31 therapy therapy NN cord-022526-j9kg00qf 3211 32 , , , cord-022526-j9kg00qf 3211 33 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 3211 34 therapy therapy NN cord-022526-j9kg00qf 3211 35 if if IN cord-022526-j9kg00qf 3211 36 indicated indicate VBN cord-022526-j9kg00qf 3211 37 , , , cord-022526-j9kg00qf 3211 38 nutritional nutritional JJ cord-022526-j9kg00qf 3211 39 support support NN cord-022526-j9kg00qf 3211 40 , , , cord-022526-j9kg00qf 3211 41 and and CC cord-022526-j9kg00qf 3211 42 nursing nursing NN cord-022526-j9kg00qf 3211 43 care care NN cord-022526-j9kg00qf 3211 44 . . . cord-022526-j9kg00qf 3212 1 One one PRP cord-022526-j9kg00qf 3212 2 should should MD cord-022526-j9kg00qf 3212 3 institute institute VB cord-022526-j9kg00qf 3212 4 aggressive aggressive JJ cord-022526-j9kg00qf 3212 5 intravenous intravenous JJ cord-022526-j9kg00qf 3212 6 polyionic polyionic JJ cord-022526-j9kg00qf 3212 7 fluid fluid NN cord-022526-j9kg00qf 3212 8 therapy therapy NN cord-022526-j9kg00qf 3212 9 immediately immediately RB cord-022526-j9kg00qf 3212 10 in in IN cord-022526-j9kg00qf 3212 11 a a DT cord-022526-j9kg00qf 3212 12 horse horse NN cord-022526-j9kg00qf 3212 13 with with IN cord-022526-j9kg00qf 3212 14 DPJ dpj NN cord-022526-j9kg00qf 3212 15 . . . cord-022526-j9kg00qf 3213 1 One one PRP cord-022526-j9kg00qf 3213 2 should should MD cord-022526-j9kg00qf 3213 3 calculate calculate VB cord-022526-j9kg00qf 3213 4 the the DT cord-022526-j9kg00qf 3213 5 total total JJ cord-022526-j9kg00qf 3213 6 fluid fluid JJ cord-022526-j9kg00qf 3213 7 deficit deficit NN cord-022526-j9kg00qf 3213 8 based base VBN cord-022526-j9kg00qf 3213 9 on on IN cord-022526-j9kg00qf 3213 10 clinical clinical JJ cord-022526-j9kg00qf 3213 11 assessment assessment NN cord-022526-j9kg00qf 3213 12 of of IN cord-022526-j9kg00qf 3213 13 dehydration dehydration NN cord-022526-j9kg00qf 3213 14 ( ( -LRB- cord-022526-j9kg00qf 3213 15 e.g. e.g. RB cord-022526-j9kg00qf 3213 16 , , , cord-022526-j9kg00qf 3213 17 for for IN cord-022526-j9kg00qf 3213 18 8 8 CD cord-022526-j9kg00qf 3213 19 % % NN cord-022526-j9kg00qf 3213 20 or or CC cord-022526-j9kg00qf 3213 21 moderate moderate JJ cord-022526-j9kg00qf 3213 22 dehydration dehydration NN cord-022526-j9kg00qf 3213 23 , , , cord-022526-j9kg00qf 3213 24 0.08 0.08 CD cord-022526-j9kg00qf 3213 25 × × NN cord-022526-j9kg00qf 3213 26 450 450 CD cord-022526-j9kg00qf 3213 27 kg kg NN cord-022526-j9kg00qf 3213 28 body body NN cord-022526-j9kg00qf 3213 29 mass mass NN cord-022526-j9kg00qf 3213 30 = = SYM cord-022526-j9kg00qf 3213 31 36 36 CD cord-022526-j9kg00qf 3213 32 L l NN cord-022526-j9kg00qf 3213 33 ) ) -RRB- cord-022526-j9kg00qf 3213 34 and and CC cord-022526-j9kg00qf 3213 35 should should MD cord-022526-j9kg00qf 3213 36 administer administer VB cord-022526-j9kg00qf 3213 37 replacement replacement NN cord-022526-j9kg00qf 3213 38 fluids fluid NNS cord-022526-j9kg00qf 3213 39 rapidly rapidly RB cord-022526-j9kg00qf 3213 40 ( ( -LRB- cord-022526-j9kg00qf 3213 41 up up IN cord-022526-j9kg00qf 3213 42 to to TO cord-022526-j9kg00qf 3213 43 6 6 CD cord-022526-j9kg00qf 3213 44 to to TO cord-022526-j9kg00qf 3213 45 10 10 CD cord-022526-j9kg00qf 3213 46 L l NN cord-022526-j9kg00qf 3213 47 per per IN cord-022526-j9kg00qf 3213 48 hour hour NN cord-022526-j9kg00qf 3213 49 per per IN cord-022526-j9kg00qf 3213 50 450-kg 450-kg CD cord-022526-j9kg00qf 3213 51 adult adult NN cord-022526-j9kg00qf 3213 52 horse horse NN cord-022526-j9kg00qf 3213 53 ) ) -RRB- cord-022526-j9kg00qf 3213 54 . . . cord-022526-j9kg00qf 3214 1 Administering administer VBG cord-022526-j9kg00qf 3214 2 intravenous intravenous JJ cord-022526-j9kg00qf 3214 3 hypertonic hypertonic NN cord-022526-j9kg00qf 3214 4 saline saline NN cord-022526-j9kg00qf 3214 5 ( ( -LRB- cord-022526-j9kg00qf 3214 6 7 7 CD cord-022526-j9kg00qf 3214 7 % % NN cord-022526-j9kg00qf 3214 8 ) ) -RRB- cord-022526-j9kg00qf 3214 9 may may MD cord-022526-j9kg00qf 3214 10 be be VB cord-022526-j9kg00qf 3214 11 useful useful JJ cord-022526-j9kg00qf 3214 12 to to TO cord-022526-j9kg00qf 3214 13 treat treat VB cord-022526-j9kg00qf 3214 14 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 3214 15 shock shock NN cord-022526-j9kg00qf 3214 16 in in IN cord-022526-j9kg00qf 3214 17 horses horse NNS cord-022526-j9kg00qf 3214 18 with with IN cord-022526-j9kg00qf 3214 19 severe severe JJ cord-022526-j9kg00qf 3214 20 circulatory circulatory JJ cord-022526-j9kg00qf 3214 21 shock shock NN cord-022526-j9kg00qf 3214 22 . . . cord-022526-j9kg00qf 3215 1 The the DT cord-022526-j9kg00qf 3215 2 use use NN cord-022526-j9kg00qf 3215 3 of of IN cord-022526-j9kg00qf 3215 4 1 1 CD cord-022526-j9kg00qf 3215 5 to to IN cord-022526-j9kg00qf 3215 6 2 2 CD cord-022526-j9kg00qf 3215 7 L l NN cord-022526-j9kg00qf 3215 8 of of IN cord-022526-j9kg00qf 3215 9 hypertonic hypertonic JJ cord-022526-j9kg00qf 3215 10 saline saline NN cord-022526-j9kg00qf 3215 11 ( ( -LRB- cord-022526-j9kg00qf 3215 12 7 7 CD cord-022526-j9kg00qf 3215 13 % % NN cord-022526-j9kg00qf 3215 14 NaCl nacl NN cord-022526-j9kg00qf 3215 15 ) ) -RRB- cord-022526-j9kg00qf 3215 16 improved improve VBN cord-022526-j9kg00qf 3215 17 systemic systemic JJ cord-022526-j9kg00qf 3215 18 blood blood NN cord-022526-j9kg00qf 3215 19 pressure pressure NN cord-022526-j9kg00qf 3215 20 and and CC cord-022526-j9kg00qf 3215 21 cardiac cardiac JJ cord-022526-j9kg00qf 3215 22 output output NN cord-022526-j9kg00qf 3215 23 in in IN cord-022526-j9kg00qf 3215 24 horses horse NNS cord-022526-j9kg00qf 3215 25 with with IN cord-022526-j9kg00qf 3215 26 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 3215 27 shock shock NN cord-022526-j9kg00qf 3215 28 and and CC cord-022526-j9kg00qf 3215 29 in in IN cord-022526-j9kg00qf 3215 30 a a DT cord-022526-j9kg00qf 3215 31 model model NN cord-022526-j9kg00qf 3215 32 of of IN cord-022526-j9kg00qf 3215 33 equine equine JJ cord-022526-j9kg00qf 3215 34 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3215 35 . . . cord-022526-j9kg00qf 3216 1 10 10 CD cord-022526-j9kg00qf 3217 1 If if IN cord-022526-j9kg00qf 3217 2 one one PRP cord-022526-j9kg00qf 3217 3 chooses choose VBZ cord-022526-j9kg00qf 3217 4 this this DT cord-022526-j9kg00qf 3217 5 treatment treatment NN cord-022526-j9kg00qf 3217 6 option option NN cord-022526-j9kg00qf 3217 7 , , , cord-022526-j9kg00qf 3217 8 intravenous intravenous JJ cord-022526-j9kg00qf 3217 9 administration administration NN cord-022526-j9kg00qf 3217 10 of of IN cord-022526-j9kg00qf 3217 11 replacement replacement NN cord-022526-j9kg00qf 3217 12 isotonic isotonic JJ cord-022526-j9kg00qf 3217 13 fluids fluid NNS cord-022526-j9kg00qf 3217 14 must must MD cord-022526-j9kg00qf 3217 15 follow follow VB cord-022526-j9kg00qf 3217 16 immediately immediately RB cord-022526-j9kg00qf 3217 17 to to TO cord-022526-j9kg00qf 3217 18 maintain maintain VB cord-022526-j9kg00qf 3217 19 tissue tissue NN cord-022526-j9kg00qf 3217 20 integrity integrity NN cord-022526-j9kg00qf 3217 21 . . . cord-022526-j9kg00qf 3218 1 One one PRP cord-022526-j9kg00qf 3218 2 should should MD cord-022526-j9kg00qf 3218 3 not not RB cord-022526-j9kg00qf 3218 4 allow allow VB cord-022526-j9kg00qf 3218 5 horses horse NNS cord-022526-j9kg00qf 3218 6 with with IN cord-022526-j9kg00qf 3218 7 significant significant JJ cord-022526-j9kg00qf 3218 8 volumes volume NNS cord-022526-j9kg00qf 3218 9 of of IN cord-022526-j9kg00qf 3218 10 gastric gastric JJ cord-022526-j9kg00qf 3218 11 reflux reflux NN cord-022526-j9kg00qf 3218 12 to to TO cord-022526-j9kg00qf 3218 13 ingest ingest VB cord-022526-j9kg00qf 3218 14 foodstuffs foodstuff NNS cord-022526-j9kg00qf 3218 15 or or CC cord-022526-j9kg00qf 3218 16 liquids liquid NNS cord-022526-j9kg00qf 3218 17 orally orally RB cord-022526-j9kg00qf 3218 18 . . . cord-022526-j9kg00qf 3219 1 Once once IN cord-022526-j9kg00qf 3219 2 one one PRP cord-022526-j9kg00qf 3219 3 has have VBZ cord-022526-j9kg00qf 3219 4 administered administer VBN cord-022526-j9kg00qf 3219 5 replacement replacement NN cord-022526-j9kg00qf 3219 6 fluids fluid NNS cord-022526-j9kg00qf 3219 7 and and CC cord-022526-j9kg00qf 3219 8 the the DT cord-022526-j9kg00qf 3219 9 horse horse NN cord-022526-j9kg00qf 3219 10 is be VBZ cord-022526-j9kg00qf 3219 11 well well RB cord-022526-j9kg00qf 3219 12 hydrated hydrated JJ cord-022526-j9kg00qf 3219 13 , , , cord-022526-j9kg00qf 3219 14 one one PRP cord-022526-j9kg00qf 3219 15 should should MD cord-022526-j9kg00qf 3219 16 administer administer VB cord-022526-j9kg00qf 3219 17 maintenance maintenance NN cord-022526-j9kg00qf 3219 18 fluid fluid NN cord-022526-j9kg00qf 3219 19 amounts amount NNS cord-022526-j9kg00qf 3219 20 , , , cord-022526-j9kg00qf 3219 21 which which WDT cord-022526-j9kg00qf 3219 22 may may MD cord-022526-j9kg00qf 3219 23 be be VB cord-022526-j9kg00qf 3219 24 as as RB cord-022526-j9kg00qf 3219 25 high high JJ cord-022526-j9kg00qf 3219 26 as as IN cord-022526-j9kg00qf 3219 27 120 120 CD cord-022526-j9kg00qf 3219 28 ml ml NNS cord-022526-j9kg00qf 3219 29 / / SYM cord-022526-j9kg00qf 3219 30 kg kg NN cord-022526-j9kg00qf 3219 31 / / SYM cord-022526-j9kg00qf 3219 32 day day NN cord-022526-j9kg00qf 3219 33 . . . cord-022526-j9kg00qf 3220 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 3220 2 , , , cord-022526-j9kg00qf 3220 3 the the DT cord-022526-j9kg00qf 3220 4 intravenous intravenous JJ cord-022526-j9kg00qf 3220 5 fluid fluid NN cord-022526-j9kg00qf 3220 6 therapy therapy NN cord-022526-j9kg00qf 3220 7 itself -PRON- PRP cord-022526-j9kg00qf 3220 8 may may MD cord-022526-j9kg00qf 3220 9 accelerate accelerate VB cord-022526-j9kg00qf 3220 10 the the DT cord-022526-j9kg00qf 3220 11 flux flux NN cord-022526-j9kg00qf 3220 12 of of IN cord-022526-j9kg00qf 3220 13 fluid fluid NN cord-022526-j9kg00qf 3220 14 from from IN cord-022526-j9kg00qf 3220 15 the the DT cord-022526-j9kg00qf 3220 16 vasculature vasculature NN cord-022526-j9kg00qf 3220 17 into into IN cord-022526-j9kg00qf 3220 18 the the DT cord-022526-j9kg00qf 3220 19 intestinal intestinal JJ cord-022526-j9kg00qf 3220 20 lumen lumen NN cord-022526-j9kg00qf 3220 21 because because IN cord-022526-j9kg00qf 3220 22 of of IN cord-022526-j9kg00qf 3220 23 a a DT cord-022526-j9kg00qf 3220 24 reduction reduction NN cord-022526-j9kg00qf 3220 25 in in IN cord-022526-j9kg00qf 3220 26 intravascular intravascular JJ cord-022526-j9kg00qf 3220 27 oncotic oncotic JJ cord-022526-j9kg00qf 3220 28 pressure pressure NN cord-022526-j9kg00qf 3220 29 and and CC cord-022526-j9kg00qf 3220 30 an an DT cord-022526-j9kg00qf 3220 31 increased increase VBN cord-022526-j9kg00qf 3220 32 capillary capillary JJ cord-022526-j9kg00qf 3220 33 perfusion perfusion NN cord-022526-j9kg00qf 3220 34 pressure pressure NN cord-022526-j9kg00qf 3220 35 , , , cord-022526-j9kg00qf 3220 36 which which WDT cord-022526-j9kg00qf 3220 37 can can MD cord-022526-j9kg00qf 3220 38 result result VB cord-022526-j9kg00qf 3220 39 in in IN cord-022526-j9kg00qf 3220 40 an an DT cord-022526-j9kg00qf 3220 41 increased increase VBN cord-022526-j9kg00qf 3220 42 volume volume NN cord-022526-j9kg00qf 3220 43 of of IN cord-022526-j9kg00qf 3220 44 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3220 45 reflux reflux NN cord-022526-j9kg00qf 3220 46 . . . cord-022526-j9kg00qf 3221 1 However however RB cord-022526-j9kg00qf 3221 2 , , , cord-022526-j9kg00qf 3221 3 the the DT cord-022526-j9kg00qf 3221 4 veterinarian veterinarian NN cord-022526-j9kg00qf 3221 5 should should MD cord-022526-j9kg00qf 3221 6 not not RB cord-022526-j9kg00qf 3221 7 consider consider VB cord-022526-j9kg00qf 3221 8 reducing reduce VBG cord-022526-j9kg00qf 3221 9 the the DT cord-022526-j9kg00qf 3221 10 volume volume NN cord-022526-j9kg00qf 3221 11 of of IN cord-022526-j9kg00qf 3221 12 intravenous intravenous JJ cord-022526-j9kg00qf 3221 13 fluid fluid NN cord-022526-j9kg00qf 3221 14 therapy therapy NN cord-022526-j9kg00qf 3221 15 because because IN cord-022526-j9kg00qf 3221 16 excessive excessive JJ cord-022526-j9kg00qf 3221 17 fluid fluid JJ cord-022526-j9kg00qf 3221 18 losses loss NNS cord-022526-j9kg00qf 3221 19 continue continue VBP cord-022526-j9kg00qf 3221 20 to to TO cord-022526-j9kg00qf 3221 21 occur occur VB cord-022526-j9kg00qf 3221 22 . . . cord-022526-j9kg00qf 3222 1 One one PRP cord-022526-j9kg00qf 3222 2 should should MD cord-022526-j9kg00qf 3222 3 monitor monitor VB cord-022526-j9kg00qf 3222 4 plasma plasma NN cord-022526-j9kg00qf 3222 5 protein protein NN cord-022526-j9kg00qf 3222 6 concentration concentration NN cord-022526-j9kg00qf 3222 7 , , , cord-022526-j9kg00qf 3222 8 overall overall JJ cord-022526-j9kg00qf 3222 9 hydration hydration NN cord-022526-j9kg00qf 3222 10 , , , cord-022526-j9kg00qf 3222 11 and and CC cord-022526-j9kg00qf 3222 12 the the DT cord-022526-j9kg00qf 3222 13 volume volume NN cord-022526-j9kg00qf 3222 14 of of IN cord-022526-j9kg00qf 3222 15 reflux reflux NN cord-022526-j9kg00qf 3222 16 and and CC cord-022526-j9kg00qf 3222 17 then then RB cord-022526-j9kg00qf 3222 18 determine determine VB cord-022526-j9kg00qf 3222 19 the the DT cord-022526-j9kg00qf 3222 20 rate rate NN cord-022526-j9kg00qf 3222 21 of of IN cord-022526-j9kg00qf 3222 22 intravenous intravenous JJ cord-022526-j9kg00qf 3222 23 fluid fluid JJ cord-022526-j9kg00qf 3222 24 administration administration NN cord-022526-j9kg00qf 3222 25 . . . cord-022526-j9kg00qf 3223 1 During during IN cord-022526-j9kg00qf 3223 2 the the DT cord-022526-j9kg00qf 3223 3 initial initial JJ cord-022526-j9kg00qf 3223 4 hours hour NNS cord-022526-j9kg00qf 3223 5 of of IN cord-022526-j9kg00qf 3223 6 therapy therapy NN cord-022526-j9kg00qf 3223 7 , , , cord-022526-j9kg00qf 3223 8 even even RB cord-022526-j9kg00qf 3223 9 aggressive aggressive JJ cord-022526-j9kg00qf 3223 10 intravenous intravenous JJ cord-022526-j9kg00qf 3223 11 fluid fluid JJ cord-022526-j9kg00qf 3223 12 administration administration NN cord-022526-j9kg00qf 3223 13 results result NNS cord-022526-j9kg00qf 3223 14 in in IN cord-022526-j9kg00qf 3223 15 only only JJ cord-022526-j9kg00qf 3223 16 moderate moderate JJ cord-022526-j9kg00qf 3223 17 clinical clinical JJ cord-022526-j9kg00qf 3223 18 improvement improvement NN cord-022526-j9kg00qf 3223 19 . . . cord-022526-j9kg00qf 3224 1 The the DT cord-022526-j9kg00qf 3224 2 clinical clinical JJ cord-022526-j9kg00qf 3224 3 response response NN cord-022526-j9kg00qf 3224 4 , , , cord-022526-j9kg00qf 3224 5 as as IN cord-022526-j9kg00qf 3224 6 evidenced evidence VBN cord-022526-j9kg00qf 3224 7 by by IN cord-022526-j9kg00qf 3224 8 improved improved JJ cord-022526-j9kg00qf 3224 9 hydration hydration NN cord-022526-j9kg00qf 3224 10 status status NN cord-022526-j9kg00qf 3224 11 , , , cord-022526-j9kg00qf 3224 12 decreased decrease VBD cord-022526-j9kg00qf 3224 13 nasogastric nasogastric NN cord-022526-j9kg00qf 3224 14 reflux reflux NN cord-022526-j9kg00qf 3224 15 , , , cord-022526-j9kg00qf 3224 16 improved improved JJ cord-022526-j9kg00qf 3224 17 attitude attitude NN cord-022526-j9kg00qf 3224 18 , , , cord-022526-j9kg00qf 3224 19 and and CC cord-022526-j9kg00qf 3224 20 improvement improvement NN cord-022526-j9kg00qf 3224 21 in in IN cord-022526-j9kg00qf 3224 22 values value NNS cord-022526-j9kg00qf 3224 23 reflecting reflect VBG cord-022526-j9kg00qf 3224 24 kidney kidney NN cord-022526-j9kg00qf 3224 25 function function NN cord-022526-j9kg00qf 3224 26 ( ( -LRB- cord-022526-j9kg00qf 3224 27 decreased decrease VBN cord-022526-j9kg00qf 3224 28 blood blood NN cord-022526-j9kg00qf 3224 29 urea urea NN cord-022526-j9kg00qf 3224 30 nitrogen nitrogen NN cord-022526-j9kg00qf 3224 31 and and CC cord-022526-j9kg00qf 3224 32 creatinine creatinine NN cord-022526-j9kg00qf 3224 33 ) ) -RRB- cord-022526-j9kg00qf 3224 34 , , , cord-022526-j9kg00qf 3224 35 correlates correlate VBZ cord-022526-j9kg00qf 3224 36 with with IN cord-022526-j9kg00qf 3224 37 improvement improvement NN cord-022526-j9kg00qf 3224 38 of of IN cord-022526-j9kg00qf 3224 39 intestinal intestinal JJ cord-022526-j9kg00qf 3224 40 damage damage NN cord-022526-j9kg00qf 3224 41 . . . cord-022526-j9kg00qf 3225 1 Horses horse NNS cord-022526-j9kg00qf 3225 2 with with IN cord-022526-j9kg00qf 3225 3 DPJ dpj NN cord-022526-j9kg00qf 3225 4 that that WDT cord-022526-j9kg00qf 3225 5 continue continue VBP cord-022526-j9kg00qf 3225 6 to to TO cord-022526-j9kg00qf 3225 7 reflux reflux VB cord-022526-j9kg00qf 3225 8 large large JJ cord-022526-j9kg00qf 3225 9 volumes volume NNS cord-022526-j9kg00qf 3225 10 of of IN cord-022526-j9kg00qf 3225 11 enterogastric enterogastric NNP cord-022526-j9kg00qf 3225 12 fluid fluid NN cord-022526-j9kg00qf 3225 13 frequently frequently RB cord-022526-j9kg00qf 3225 14 for for IN cord-022526-j9kg00qf 3225 15 more more JJR cord-022526-j9kg00qf 3225 16 than than IN cord-022526-j9kg00qf 3225 17 36 36 CD cord-022526-j9kg00qf 3225 18 to to TO cord-022526-j9kg00qf 3225 19 48 48 CD cord-022526-j9kg00qf 3225 20 hours hour NNS cord-022526-j9kg00qf 3225 21 most most RBS cord-022526-j9kg00qf 3225 22 likely likely RB cord-022526-j9kg00qf 3225 23 will will MD cord-022526-j9kg00qf 3225 24 experience experience VB cord-022526-j9kg00qf 3225 25 protein protein NN cord-022526-j9kg00qf 3225 26 loss loss NN cord-022526-j9kg00qf 3225 27 from from IN cord-022526-j9kg00qf 3225 28 the the DT cord-022526-j9kg00qf 3225 29 inflamed inflamed JJ cord-022526-j9kg00qf 3225 30 and and CC cord-022526-j9kg00qf 3225 31 disrupted disrupt VBD cord-022526-j9kg00qf 3225 32 intestinal intestinal JJ cord-022526-j9kg00qf 3225 33 mucosal mucosal JJ cord-022526-j9kg00qf 3225 34 barrier barrier NN cord-022526-j9kg00qf 3225 35 and and CC cord-022526-j9kg00qf 3225 36 from from IN cord-022526-j9kg00qf 3225 37 systemic systemic JJ cord-022526-j9kg00qf 3225 38 protein protein NN cord-022526-j9kg00qf 3225 39 catabolism catabolism NN cord-022526-j9kg00qf 3225 40 . . . cord-022526-j9kg00qf 3226 1 Decreased decrease VBN cord-022526-j9kg00qf 3226 2 colloid colloid NN cord-022526-j9kg00qf 3226 3 oncotic oncotic JJ cord-022526-j9kg00qf 3226 4 pressure pressure NN cord-022526-j9kg00qf 3226 5 leads lead VBZ cord-022526-j9kg00qf 3226 6 to to IN cord-022526-j9kg00qf 3226 7 decreased decrease VBD cord-022526-j9kg00qf 3226 8 effective effective JJ cord-022526-j9kg00qf 3226 9 circulating circulate VBG cord-022526-j9kg00qf 3226 10 fluid fluid JJ cord-022526-j9kg00qf 3226 11 volume volume NN cord-022526-j9kg00qf 3226 12 and and CC cord-022526-j9kg00qf 3226 13 edema edema NN cord-022526-j9kg00qf 3226 14 . . . cord-022526-j9kg00qf 3227 1 Total total JJ cord-022526-j9kg00qf 3227 2 plasma plasma NN cord-022526-j9kg00qf 3227 3 protein protein NN cord-022526-j9kg00qf 3227 4 may may MD cord-022526-j9kg00qf 3227 5 decline decline VB cord-022526-j9kg00qf 3227 6 to to IN cord-022526-j9kg00qf 3227 7 below below IN cord-022526-j9kg00qf 3227 8 4 4 CD cord-022526-j9kg00qf 3227 9 g g NN cord-022526-j9kg00qf 3227 10 / / SYM cord-022526-j9kg00qf 3227 11 dl dl NN cord-022526-j9kg00qf 3227 12 and and CC cord-022526-j9kg00qf 3227 13 the the DT cord-022526-j9kg00qf 3227 14 albumin albumin NN cord-022526-j9kg00qf 3227 15 may may MD cord-022526-j9kg00qf 3227 16 decrease decrease VB cord-022526-j9kg00qf 3227 17 to to IN cord-022526-j9kg00qf 3227 18 below below IN cord-022526-j9kg00qf 3227 19 2.0 2.0 CD cord-022526-j9kg00qf 3227 20 g g NN cord-022526-j9kg00qf 3227 21 / / SYM cord-022526-j9kg00qf 3227 22 dl dl NN cord-022526-j9kg00qf 3227 23 . . . cord-022526-j9kg00qf 3228 1 Fresh fresh JJ cord-022526-j9kg00qf 3228 2 or or CC cord-022526-j9kg00qf 3228 3 thawed thaw VBD cord-022526-j9kg00qf 3228 4 frozen frozen JJ cord-022526-j9kg00qf 3228 5 plasma plasma NN cord-022526-j9kg00qf 3228 6 is be VBZ cord-022526-j9kg00qf 3228 7 ideal ideal JJ cord-022526-j9kg00qf 3228 8 for for IN cord-022526-j9kg00qf 3228 9 replacement replacement NN cord-022526-j9kg00qf 3228 10 of of IN cord-022526-j9kg00qf 3228 11 functional functional JJ cord-022526-j9kg00qf 3228 12 proteins protein NNS cord-022526-j9kg00qf 3228 13 . . . cord-022526-j9kg00qf 3229 1 One one PRP cord-022526-j9kg00qf 3229 2 should should MD cord-022526-j9kg00qf 3229 3 consider consider VB cord-022526-j9kg00qf 3229 4 treatment treatment NN cord-022526-j9kg00qf 3229 5 with with IN cord-022526-j9kg00qf 3229 6 intravenous intravenous JJ cord-022526-j9kg00qf 3229 7 plasma plasma NN cord-022526-j9kg00qf 3229 8 therapy therapy NN cord-022526-j9kg00qf 3229 9 or or CC cord-022526-j9kg00qf 3229 10 a a DT cord-022526-j9kg00qf 3229 11 combination combination NN cord-022526-j9kg00qf 3229 12 of of IN cord-022526-j9kg00qf 3229 13 plasma plasma NN cord-022526-j9kg00qf 3229 14 and and CC cord-022526-j9kg00qf 3229 15 synthetic synthetic JJ cord-022526-j9kg00qf 3229 16 colloid colloid NN cord-022526-j9kg00qf 3229 17 ( ( -LRB- cord-022526-j9kg00qf 3229 18 e.g. e.g. RB cord-022526-j9kg00qf 3229 19 , , , cord-022526-j9kg00qf 3229 20 synthetic synthetic JJ cord-022526-j9kg00qf 3229 21 amylopectin amylopectin NNS cord-022526-j9kg00qf 3229 22 ) ) -RRB- cord-022526-j9kg00qf 3229 23 as as RB cord-022526-j9kg00qf 3229 24 soon soon RB cord-022526-j9kg00qf 3229 25 as as IN cord-022526-j9kg00qf 3229 26 one one PRP cord-022526-j9kg00qf 3229 27 sees see VBZ cord-022526-j9kg00qf 3229 28 evidence evidence NN cord-022526-j9kg00qf 3229 29 of of IN cord-022526-j9kg00qf 3229 30 a a DT cord-022526-j9kg00qf 3229 31 consistent consistent JJ cord-022526-j9kg00qf 3229 32 decline decline NN cord-022526-j9kg00qf 3229 33 in in IN cord-022526-j9kg00qf 3229 34 total total JJ cord-022526-j9kg00qf 3229 35 plasma plasma NN cord-022526-j9kg00qf 3229 36 protein protein NN cord-022526-j9kg00qf 3229 37 or or CC cord-022526-j9kg00qf 3229 38 albumin albumin NN cord-022526-j9kg00qf 3229 39 ( ( -LRB- cord-022526-j9kg00qf 3229 40 < < NNP cord-022526-j9kg00qf 3229 41 2.0 2.0 CD cord-022526-j9kg00qf 3229 42 g g NN cord-022526-j9kg00qf 3229 43 / / SYM cord-022526-j9kg00qf 3229 44 dl dl NN cord-022526-j9kg00qf 3229 45 ) ) -RRB- cord-022526-j9kg00qf 3229 46 or or CC cord-022526-j9kg00qf 3229 47 if if IN cord-022526-j9kg00qf 3229 48 the the DT cord-022526-j9kg00qf 3229 49 horse horse NN cord-022526-j9kg00qf 3229 50 is be VBZ cord-022526-j9kg00qf 3229 51 developing develop VBG cord-022526-j9kg00qf 3229 52 dependent dependent JJ cord-022526-j9kg00qf 3229 53 edema edema NN cord-022526-j9kg00qf 3229 54 . . . cord-022526-j9kg00qf 3230 1 Fresh fresh JJ cord-022526-j9kg00qf 3230 2 plasma plasma NN cord-022526-j9kg00qf 3230 3 ( ( -LRB- cord-022526-j9kg00qf 3230 4 preferred preferred JJ cord-022526-j9kg00qf 3230 5 ) ) -RRB- cord-022526-j9kg00qf 3230 6 or or CC cord-022526-j9kg00qf 3230 7 fresh fresh JJ cord-022526-j9kg00qf 3230 8 frozen frozen JJ cord-022526-j9kg00qf 3230 9 plasma plasma NN cord-022526-j9kg00qf 3230 10 is be VBZ cord-022526-j9kg00qf 3230 11 the the DT cord-022526-j9kg00qf 3230 12 treatment treatment NN cord-022526-j9kg00qf 3230 13 of of IN cord-022526-j9kg00qf 3230 14 choice choice NN cord-022526-j9kg00qf 3230 15 if if IN cord-022526-j9kg00qf 3230 16 coagulation coagulation NN cord-022526-j9kg00qf 3230 17 disorders disorder NNS cord-022526-j9kg00qf 3230 18 accompany accompany VBP cord-022526-j9kg00qf 3230 19 protein protein NN cord-022526-j9kg00qf 3230 20 loss loss NN cord-022526-j9kg00qf 3230 21 . . . cord-022526-j9kg00qf 3231 1 An an DT cord-022526-j9kg00qf 3231 2 average average JJ cord-022526-j9kg00qf 3231 3 - - HYPH cord-022526-j9kg00qf 3231 4 size size NN cord-022526-j9kg00qf 3231 5 horse horse NN cord-022526-j9kg00qf 3231 6 ( ( -LRB- cord-022526-j9kg00qf 3231 7 450 450 CD cord-022526-j9kg00qf 3231 8 kg kg NNS cord-022526-j9kg00qf 3231 9 ) ) -RRB- cord-022526-j9kg00qf 3231 10 requires require VBZ cord-022526-j9kg00qf 3231 11 6 6 CD cord-022526-j9kg00qf 3231 12 to to TO cord-022526-j9kg00qf 3231 13 10 10 CD cord-022526-j9kg00qf 3231 14 L l NN cord-022526-j9kg00qf 3231 15 of of IN cord-022526-j9kg00qf 3231 16 plasma plasma NN cord-022526-j9kg00qf 3231 17 ( ( -LRB- cord-022526-j9kg00qf 3231 18 albumin albumin NN cord-022526-j9kg00qf 3231 19 3.0 3.0 CD cord-022526-j9kg00qf 3231 20 g g NN cord-022526-j9kg00qf 3231 21 / / SYM cord-022526-j9kg00qf 3231 22 dl dl NN cord-022526-j9kg00qf 3231 23 ) ) -RRB- cord-022526-j9kg00qf 3231 24 or or CC cord-022526-j9kg00qf 3231 25 synthetic synthetic JJ cord-022526-j9kg00qf 3231 26 colloid colloid NN cord-022526-j9kg00qf 3231 27 to to TO cord-022526-j9kg00qf 3231 28 improve improve VB cord-022526-j9kg00qf 3231 29 plasma plasma NN cord-022526-j9kg00qf 3231 30 oncotic oncotic JJ cord-022526-j9kg00qf 3231 31 pressure pressure NN cord-022526-j9kg00qf 3231 32 . . . cord-022526-j9kg00qf 3232 1 Administration administration NN cord-022526-j9kg00qf 3232 2 of of IN cord-022526-j9kg00qf 3232 3 additional additional JJ cord-022526-j9kg00qf 3232 4 aliquots aliquot NNS cord-022526-j9kg00qf 3232 5 of of IN cord-022526-j9kg00qf 3232 6 2 2 CD cord-022526-j9kg00qf 3232 7 to to TO cord-022526-j9kg00qf 3232 8 10 10 CD cord-022526-j9kg00qf 3232 9 L l NN cord-022526-j9kg00qf 3232 10 of of IN cord-022526-j9kg00qf 3232 11 a a DT cord-022526-j9kg00qf 3232 12 balanced balanced JJ cord-022526-j9kg00qf 3232 13 colloidal colloidal NN cord-022526-j9kg00qf 3232 14 solution solution NN cord-022526-j9kg00qf 3232 15 may may MD cord-022526-j9kg00qf 3232 16 be be VB cord-022526-j9kg00qf 3232 17 necessary necessary JJ cord-022526-j9kg00qf 3232 18 if if IN cord-022526-j9kg00qf 3232 19 the the DT cord-022526-j9kg00qf 3232 20 DPJ dpj NN cord-022526-j9kg00qf 3232 21 crisis crisis NN cord-022526-j9kg00qf 3232 22 continues continue VBZ cord-022526-j9kg00qf 3232 23 . . . cord-022526-j9kg00qf 3233 1 In in IN cord-022526-j9kg00qf 3233 2 addition addition NN cord-022526-j9kg00qf 3233 3 to to IN cord-022526-j9kg00qf 3233 4 albumin albumin NN cord-022526-j9kg00qf 3233 5 ( ( -LRB- cord-022526-j9kg00qf 3233 6 the the DT cord-022526-j9kg00qf 3233 7 major major JJ cord-022526-j9kg00qf 3233 8 colloid colloid NN cord-022526-j9kg00qf 3233 9 component component NN cord-022526-j9kg00qf 3233 10 ) ) -RRB- cord-022526-j9kg00qf 3233 11 , , , cord-022526-j9kg00qf 3233 12 plasma plasma NN cord-022526-j9kg00qf 3233 13 contains contain VBZ cord-022526-j9kg00qf 3233 14 other other JJ cord-022526-j9kg00qf 3233 15 components component NNS cord-022526-j9kg00qf 3233 16 that that WDT cord-022526-j9kg00qf 3233 17 provide provide VBP cord-022526-j9kg00qf 3233 18 overall overall JJ cord-022526-j9kg00qf 3233 19 systemic systemic JJ cord-022526-j9kg00qf 3233 20 support support NN cord-022526-j9kg00qf 3233 21 ( ( -LRB- cord-022526-j9kg00qf 3233 22 e.g. e.g. RB cord-022526-j9kg00qf 3233 23 , , , cord-022526-j9kg00qf 3233 24 fibronectins fibronectin NNS cord-022526-j9kg00qf 3233 25 , , , cord-022526-j9kg00qf 3233 26 complement complement NN cord-022526-j9kg00qf 3233 27 inhibitors inhibitor NNS cord-022526-j9kg00qf 3233 28 , , , cord-022526-j9kg00qf 3233 29 elastase elastase NN cord-022526-j9kg00qf 3233 30 and and CC cord-022526-j9kg00qf 3233 31 proteinase proteinase NN cord-022526-j9kg00qf 3233 32 inhibitors inhibitor NNS cord-022526-j9kg00qf 3233 33 , , , cord-022526-j9kg00qf 3233 34 antithrombin antithrombin NN cord-022526-j9kg00qf 3233 35 III III NNP cord-022526-j9kg00qf 3233 36 ) ) -RRB- cord-022526-j9kg00qf 3233 37 . . . cord-022526-j9kg00qf 3234 1 One one CD cord-022526-j9kg00qf 3234 2 may may MD cord-022526-j9kg00qf 3234 3 administer administer VB cord-022526-j9kg00qf 3234 4 a a DT cord-022526-j9kg00qf 3234 5 6 6 CD cord-022526-j9kg00qf 3234 6 % % NN cord-022526-j9kg00qf 3234 7 solution solution NN cord-022526-j9kg00qf 3234 8 of of IN cord-022526-j9kg00qf 3234 9 hydroxyethyl hydroxyethyl NN cord-022526-j9kg00qf 3234 10 starch starch NN cord-022526-j9kg00qf 3234 11 ( ( -LRB- cord-022526-j9kg00qf 3234 12 Hetastarch Hetastarch NNP cord-022526-j9kg00qf 3234 13 ( ( -LRB- cord-022526-j9kg00qf 3234 14 6 6 CD cord-022526-j9kg00qf 3234 15 % % NN cord-022526-j9kg00qf 3234 16 ) ) -RRB- cord-022526-j9kg00qf 3234 17 , , , cord-022526-j9kg00qf 3234 18 Abbott Abbott NNP cord-022526-j9kg00qf 3234 19 Laboratories Laboratories NNP cord-022526-j9kg00qf 3234 20 , , , cord-022526-j9kg00qf 3234 21 North North NNP cord-022526-j9kg00qf 3234 22 Chicago Chicago NNP cord-022526-j9kg00qf 3234 23 , , , cord-022526-j9kg00qf 3234 24 Illinois Illinois NNP cord-022526-j9kg00qf 3234 25 ) ) -RRB- cord-022526-j9kg00qf 3234 26 , , , cord-022526-j9kg00qf 3234 27 a a DT cord-022526-j9kg00qf 3234 28 synthetic synthetic JJ cord-022526-j9kg00qf 3234 29 colloid colloid NN cord-022526-j9kg00qf 3234 30 , , , cord-022526-j9kg00qf 3234 31 at at IN cord-022526-j9kg00qf 3234 32 5 5 CD cord-022526-j9kg00qf 3234 33 to to TO cord-022526-j9kg00qf 3234 34 10 10 CD cord-022526-j9kg00qf 3234 35 ml ml NNS cord-022526-j9kg00qf 3234 36 / / SYM cord-022526-j9kg00qf 3234 37 kg kg NNS cord-022526-j9kg00qf 3234 38 . . . cord-022526-j9kg00qf 3235 1 Because because IN cord-022526-j9kg00qf 3235 2 of of IN cord-022526-j9kg00qf 3235 3 the the DT cord-022526-j9kg00qf 3235 4 large large JJ cord-022526-j9kg00qf 3235 5 size size NN cord-022526-j9kg00qf 3235 6 of of IN cord-022526-j9kg00qf 3235 7 the the DT cord-022526-j9kg00qf 3235 8 starch starch NN cord-022526-j9kg00qf 3235 9 molecules molecule NNS cord-022526-j9kg00qf 3235 10 , , , cord-022526-j9kg00qf 3235 11 this this DT cord-022526-j9kg00qf 3235 12 solution solution NN cord-022526-j9kg00qf 3235 13 is be VBZ cord-022526-j9kg00qf 3235 14 an an DT cord-022526-j9kg00qf 3235 15 effective effective JJ cord-022526-j9kg00qf 3235 16 plasma plasma NN cord-022526-j9kg00qf 3235 17 volume volume NN cord-022526-j9kg00qf 3235 18 expander expander NN cord-022526-j9kg00qf 3235 19 , , , cord-022526-j9kg00qf 3235 20 resulting result VBG cord-022526-j9kg00qf 3235 21 in in IN cord-022526-j9kg00qf 3235 22 sustained sustained JJ cord-022526-j9kg00qf 3235 23 dosedependent dosedependent NN cord-022526-j9kg00qf 3235 24 decreases decrease NNS cord-022526-j9kg00qf 3235 25 in in IN cord-022526-j9kg00qf 3235 26 packed pack VBN cord-022526-j9kg00qf 3235 27 cell cell NN cord-022526-j9kg00qf 3235 28 volume volume NN cord-022526-j9kg00qf 3235 29 and and CC cord-022526-j9kg00qf 3235 30 plasma plasma NN cord-022526-j9kg00qf 3235 31 protein protein NN cord-022526-j9kg00qf 3235 32 concentration concentration NN cord-022526-j9kg00qf 3235 33 with with IN cord-022526-j9kg00qf 3235 34 increased increase VBN cord-022526-j9kg00qf 3235 35 oncotic oncotic JJ cord-022526-j9kg00qf 3235 36 pressure pressure NN cord-022526-j9kg00qf 3235 37 . . . cord-022526-j9kg00qf 3236 1 The the DT cord-022526-j9kg00qf 3236 2 cost cost NN cord-022526-j9kg00qf 3236 3 of of IN cord-022526-j9kg00qf 3236 4 an an DT cord-022526-j9kg00qf 3236 5 appropriate appropriate JJ cord-022526-j9kg00qf 3236 6 amount amount NN cord-022526-j9kg00qf 3236 7 of of IN cord-022526-j9kg00qf 3236 8 commercial commercial JJ cord-022526-j9kg00qf 3236 9 plasma plasma NN cord-022526-j9kg00qf 3236 10 or or CC cord-022526-j9kg00qf 3236 11 synthetic synthetic JJ cord-022526-j9kg00qf 3236 12 colloid colloid NN cord-022526-j9kg00qf 3236 13 solution solution NN cord-022526-j9kg00qf 3236 14 for for IN cord-022526-j9kg00qf 3236 15 treatment treatment NN cord-022526-j9kg00qf 3236 16 of of IN cord-022526-j9kg00qf 3236 17 adult adult NN cord-022526-j9kg00qf 3236 18 horses horse NNS cord-022526-j9kg00qf 3236 19 with with IN cord-022526-j9kg00qf 3236 20 DPJ dpj NN cord-022526-j9kg00qf 3236 21 may may MD cord-022526-j9kg00qf 3236 22 be be VB cord-022526-j9kg00qf 3236 23 prohibitive prohibitive JJ cord-022526-j9kg00qf 3236 24 but but CC cord-022526-j9kg00qf 3236 25 can can MD cord-022526-j9kg00qf 3236 26 be be VB cord-022526-j9kg00qf 3236 27 life life NN cord-022526-j9kg00qf 3236 28 - - HYPH cord-022526-j9kg00qf 3236 29 saving save VBG cord-022526-j9kg00qf 3236 30 . . . cord-022526-j9kg00qf 3237 1 Horses horse NNS cord-022526-j9kg00qf 3237 2 with with IN cord-022526-j9kg00qf 3237 3 enteritis enteritis NN cord-022526-j9kg00qf 3237 4 frequently frequently RB cord-022526-j9kg00qf 3237 5 absorb absorb VB cord-022526-j9kg00qf 3237 6 large large JJ cord-022526-j9kg00qf 3237 7 amounts amount NNS cord-022526-j9kg00qf 3237 8 of of IN cord-022526-j9kg00qf 3237 9 endotoxin endotoxin NN cord-022526-j9kg00qf 3237 10 from from IN cord-022526-j9kg00qf 3237 11 the the DT cord-022526-j9kg00qf 3237 12 disrupted disrupt VBN cord-022526-j9kg00qf 3237 13 intestinal intestinal JJ cord-022526-j9kg00qf 3237 14 mucosal mucosal JJ cord-022526-j9kg00qf 3237 15 barrier barrier NN cord-022526-j9kg00qf 3237 16 , , , cord-022526-j9kg00qf 3237 17 therefore therefore RB cord-022526-j9kg00qf 3237 18 putting put VBG cord-022526-j9kg00qf 3237 19 these these DT cord-022526-j9kg00qf 3237 20 horses horse NNS cord-022526-j9kg00qf 3237 21 at at IN cord-022526-j9kg00qf 3237 22 a a DT cord-022526-j9kg00qf 3237 23 high high JJ cord-022526-j9kg00qf 3237 24 risk risk NN cord-022526-j9kg00qf 3237 25 for for IN cord-022526-j9kg00qf 3237 26 laminitis laminitis NN cord-022526-j9kg00qf 3237 27 . . . cord-022526-j9kg00qf 3238 1 One one PRP cord-022526-j9kg00qf 3238 2 should should MD cord-022526-j9kg00qf 3238 3 monitor monitor VB cord-022526-j9kg00qf 3238 4 digital digital JJ cord-022526-j9kg00qf 3238 5 pulses pulse NNS cord-022526-j9kg00qf 3238 6 every every DT cord-022526-j9kg00qf 3238 7 4 4 CD cord-022526-j9kg00qf 3238 8 to to TO cord-022526-j9kg00qf 3238 9 6 6 CD cord-022526-j9kg00qf 3238 10 hours hour NNS cord-022526-j9kg00qf 3238 11 until until IN cord-022526-j9kg00qf 3238 12 systemic systemic JJ cord-022526-j9kg00qf 3238 13 signs sign NNS cord-022526-j9kg00qf 3238 14 of of IN cord-022526-j9kg00qf 3238 15 enteritis enteritis NN cord-022526-j9kg00qf 3238 16 have have VBP cord-022526-j9kg00qf 3238 17 abated abate VBN cord-022526-j9kg00qf 3238 18 ( ( -LRB- cord-022526-j9kg00qf 3238 19 fever fever NN cord-022526-j9kg00qf 3238 20 , , , cord-022526-j9kg00qf 3238 21 leukopenia leukopenia NN cord-022526-j9kg00qf 3238 22 , , , cord-022526-j9kg00qf 3238 23 etc etc FW cord-022526-j9kg00qf 3238 24 . . . cord-022526-j9kg00qf 3238 25 ) ) -RRB- cord-022526-j9kg00qf 3238 26 . . . cord-022526-j9kg00qf 3239 1 Treatment treatment NN cord-022526-j9kg00qf 3239 2 to to TO cord-022526-j9kg00qf 3239 3 combat combat VB cord-022526-j9kg00qf 3239 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3239 5 is be VBZ cord-022526-j9kg00qf 3239 6 critical critical JJ cord-022526-j9kg00qf 3239 7 , , , cord-022526-j9kg00qf 3239 8 and and CC cord-022526-j9kg00qf 3239 9 several several JJ cord-022526-j9kg00qf 3239 10 therapeutic therapeutic JJ cord-022526-j9kg00qf 3239 11 approaches approach NNS cord-022526-j9kg00qf 3239 12 are be VBP cord-022526-j9kg00qf 3239 13 available available JJ cord-022526-j9kg00qf 3239 14 . . . cord-022526-j9kg00qf 3240 1 Choice choice NN cord-022526-j9kg00qf 3240 2 of of IN cord-022526-j9kg00qf 3240 3 treatment treatment NN cord-022526-j9kg00qf 3240 4 options option NNS cord-022526-j9kg00qf 3240 5 is be VBZ cord-022526-j9kg00qf 3240 6 based base VBN cord-022526-j9kg00qf 3240 7 on on IN cord-022526-j9kg00qf 3240 8 severity severity NN cord-022526-j9kg00qf 3240 9 of of IN cord-022526-j9kg00qf 3240 10 disease disease NN cord-022526-j9kg00qf 3240 11 , , , cord-022526-j9kg00qf 3240 12 renal renal JJ cord-022526-j9kg00qf 3240 13 function function NN cord-022526-j9kg00qf 3240 14 , , , cord-022526-j9kg00qf 3240 15 hydration hydration NN cord-022526-j9kg00qf 3240 16 status status NN cord-022526-j9kg00qf 3240 17 , , , cord-022526-j9kg00qf 3240 18 and and CC cord-022526-j9kg00qf 3240 19 economics economic NNS cord-022526-j9kg00qf 3240 20 . . . cord-022526-j9kg00qf 3241 1 The the DT cord-022526-j9kg00qf 3241 2 reader reader NN cord-022526-j9kg00qf 3241 3 is be VBZ cord-022526-j9kg00qf 3241 4 referred refer VBN cord-022526-j9kg00qf 3241 5 to to IN cord-022526-j9kg00qf 3241 6 Chapter chapter NN cord-022526-j9kg00qf 3241 7 13.7 13.7 CD cord-022526-j9kg00qf 3241 8 for for IN cord-022526-j9kg00qf 3241 9 a a DT cord-022526-j9kg00qf 3241 10 thorough thorough JJ cord-022526-j9kg00qf 3241 11 discussion discussion NN cord-022526-j9kg00qf 3241 12 of of IN cord-022526-j9kg00qf 3241 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3241 14 pathophysiology pathophysiology NN cord-022526-j9kg00qf 3241 15 , , , cord-022526-j9kg00qf 3241 16 treatment treatment NN cord-022526-j9kg00qf 3241 17 , , , cord-022526-j9kg00qf 3241 18 and and CC cord-022526-j9kg00qf 3241 19 prevention prevention NN cord-022526-j9kg00qf 3241 20 . . . cord-022526-j9kg00qf 3242 1 Nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 3242 2 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3242 3 drugs drug NNS cord-022526-j9kg00qf 3242 4 are be VBP cord-022526-j9kg00qf 3242 5 the the DT cord-022526-j9kg00qf 3242 6 most most RBS cord-022526-j9kg00qf 3242 7 frequently frequently RB cord-022526-j9kg00qf 3242 8 used use VBN cord-022526-j9kg00qf 3242 9 group group NN cord-022526-j9kg00qf 3242 10 of of IN cord-022526-j9kg00qf 3242 11 drugs drug NNS cord-022526-j9kg00qf 3242 12 for for IN cord-022526-j9kg00qf 3242 13 treatment treatment NN cord-022526-j9kg00qf 3242 14 of of IN cord-022526-j9kg00qf 3242 15 abdominal abdominal JJ cord-022526-j9kg00qf 3242 16 pain pain NN cord-022526-j9kg00qf 3242 17 in in IN cord-022526-j9kg00qf 3242 18 horses horse NNS cord-022526-j9kg00qf 3242 19 ( ( -LRB- cord-022526-j9kg00qf 3242 20 flunixin flunixin NNP cord-022526-j9kg00qf 3242 21 meglumine meglumine NNP cord-022526-j9kg00qf 3242 22 1.1 1.1 CD cord-022526-j9kg00qf 3242 23 mg mg NNP cord-022526-j9kg00qf 3242 24 / / SYM cord-022526-j9kg00qf 3242 25 kg kg XX cord-022526-j9kg00qf 3242 26 intravenously intravenously RB cord-022526-j9kg00qf 3242 27 every every DT cord-022526-j9kg00qf 3242 28 12 12 CD cord-022526-j9kg00qf 3242 29 hours hour NNS cord-022526-j9kg00qf 3242 30 or or CC cord-022526-j9kg00qf 3242 31 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 3243 1 2.2 2.2 CD cord-022526-j9kg00qf 3243 2 mg mg NNP cord-022526-j9kg00qf 3243 3 / / SYM cord-022526-j9kg00qf 3243 4 kg kg XX cord-022526-j9kg00qf 3243 5 orally orally RB cord-022526-j9kg00qf 3243 6 or or CC cord-022526-j9kg00qf 3243 7 intravenously intravenously RB cord-022526-j9kg00qf 3243 8 every every DT cord-022526-j9kg00qf 3243 9 12 12 CD cord-022526-j9kg00qf 3243 10 hours hour NNS cord-022526-j9kg00qf 3243 11 ) ) -RRB- cord-022526-j9kg00qf 3243 12 . . . cord-022526-j9kg00qf 3244 1 The the DT cord-022526-j9kg00qf 3244 2 clinician clinician NN cord-022526-j9kg00qf 3244 3 must must MD cord-022526-j9kg00qf 3244 4 weigh weigh VB cord-022526-j9kg00qf 3244 5 the the DT cord-022526-j9kg00qf 3244 6 benefit benefit NN cord-022526-j9kg00qf 3244 7 of of IN cord-022526-j9kg00qf 3244 8 the the DT cord-022526-j9kg00qf 3244 9 analgesic analgesic JJ cord-022526-j9kg00qf 3244 10 effect effect NN cord-022526-j9kg00qf 3244 11 of of IN cord-022526-j9kg00qf 3244 12 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 3244 13 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3244 14 drugs drug NNS cord-022526-j9kg00qf 3244 15 with with IN cord-022526-j9kg00qf 3244 16 the the DT cord-022526-j9kg00qf 3244 17 possibility possibility NN cord-022526-j9kg00qf 3244 18 of of IN cord-022526-j9kg00qf 3244 19 further further JJ cord-022526-j9kg00qf 3244 20 damage damage NN cord-022526-j9kg00qf 3244 21 to to IN cord-022526-j9kg00qf 3244 22 the the DT cord-022526-j9kg00qf 3244 23 intestine intestine NN cord-022526-j9kg00qf 3244 24 by by IN cord-022526-j9kg00qf 3244 25 potentially potentially RB cord-022526-j9kg00qf 3244 26 blocking block VBG cord-022526-j9kg00qf 3244 27 the the DT cord-022526-j9kg00qf 3244 28 protective protective JJ cord-022526-j9kg00qf 3244 29 effects effect NNS cord-022526-j9kg00qf 3244 30 of of IN cord-022526-j9kg00qf 3244 31 intestinal intestinal JJ cord-022526-j9kg00qf 3244 32 mucosal mucosal JJ cord-022526-j9kg00qf 3244 33 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 3244 34 . . . cord-022526-j9kg00qf 3245 1 One one PRP cord-022526-j9kg00qf 3245 2 should should MD cord-022526-j9kg00qf 3245 3 consider consider VB cord-022526-j9kg00qf 3245 4 other other JJ cord-022526-j9kg00qf 3245 5 classes class NNS cord-022526-j9kg00qf 3245 6 of of IN cord-022526-j9kg00qf 3245 7 drugs drug NNS cord-022526-j9kg00qf 3245 8 for for IN cord-022526-j9kg00qf 3245 9 treating treat VBG cord-022526-j9kg00qf 3245 10 colic colic NN cord-022526-j9kg00qf 3245 11 associated associate VBN cord-022526-j9kg00qf 3245 12 with with IN cord-022526-j9kg00qf 3245 13 DPJ dpj NN cord-022526-j9kg00qf 3245 14 . . . cord-022526-j9kg00qf 3246 1 Butorphanol Butorphanol NNP cord-022526-j9kg00qf 3246 2 ( ( -LRB- cord-022526-j9kg00qf 3246 3 Torbugesic Torbugesic NNP cord-022526-j9kg00qf 3246 4 ; ; : cord-022526-j9kg00qf 3246 5 an an DT cord-022526-j9kg00qf 3246 6 opioid opioid JJ cord-022526-j9kg00qf 3246 7 analgesic analgesic NN cord-022526-j9kg00qf 3246 8 ) ) -RRB- cord-022526-j9kg00qf 3246 9 at at IN cord-022526-j9kg00qf 3246 10 0.06 0.06 CD cord-022526-j9kg00qf 3246 11 to to IN cord-022526-j9kg00qf 3246 12 0.1 0.1 CD cord-022526-j9kg00qf 3246 13 mg mg NNP cord-022526-j9kg00qf 3246 14 / / SYM cord-022526-j9kg00qf 3246 15 kg kg NNS cord-022526-j9kg00qf 3246 16 with with IN cord-022526-j9kg00qf 3246 17 detomidine detomidine NN cord-022526-j9kg00qf 3246 18 ( ( -LRB- cord-022526-j9kg00qf 3246 19 Dormosedan Dormosedan NNP cord-022526-j9kg00qf 3246 20 ; ; : cord-022526-j9kg00qf 3246 21 an an DT cord-022526-j9kg00qf 3246 22 α α NN cord-022526-j9kg00qf 3246 23 - - HYPH cord-022526-j9kg00qf 3246 24 agonist agonist NN cord-022526-j9kg00qf 3246 25 ) ) -RRB- cord-022526-j9kg00qf 3246 26 at at IN cord-022526-j9kg00qf 3246 27 0.01 0.01 CD cord-022526-j9kg00qf 3246 28 to to IN cord-022526-j9kg00qf 3246 29 0.02 0.02 CD cord-022526-j9kg00qf 3246 30 mg mg NNP cord-022526-j9kg00qf 3246 31 / / SYM cord-022526-j9kg00qf 3246 32 kg kg NNS cord-022526-j9kg00qf 3246 33 given give VBN cord-022526-j9kg00qf 3246 34 intramuscularly intramuscularly RB cord-022526-j9kg00qf 3246 35 every every DT cord-022526-j9kg00qf 3246 36 6 6 CD cord-022526-j9kg00qf 3246 37 to to TO cord-022526-j9kg00qf 3246 38 8 8 CD cord-022526-j9kg00qf 3246 39 hours hour NNS cord-022526-j9kg00qf 3246 40 is be VBZ cord-022526-j9kg00qf 3246 41 a a DT cord-022526-j9kg00qf 3246 42 useful useful JJ cord-022526-j9kg00qf 3246 43 combination combination NN cord-022526-j9kg00qf 3246 44 that that WDT cord-022526-j9kg00qf 3246 45 has have VBZ cord-022526-j9kg00qf 3246 46 minimal minimal JJ cord-022526-j9kg00qf 3246 47 effects effect NNS cord-022526-j9kg00qf 3246 48 on on IN cord-022526-j9kg00qf 3246 49 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3246 50 motility motility NN cord-022526-j9kg00qf 3246 51 . . . cord-022526-j9kg00qf 3247 1 Because because IN cord-022526-j9kg00qf 3247 2 Clostridium clostridium NN cord-022526-j9kg00qf 3247 3 spp spp NNS cord-022526-j9kg00qf 3247 4 . . . cord-022526-j9kg00qf 3248 1 are be VBP cord-022526-j9kg00qf 3248 2 suspected suspect VBN cord-022526-j9kg00qf 3248 3 as as IN cord-022526-j9kg00qf 3248 4 a a DT cord-022526-j9kg00qf 3248 5 causative causative JJ cord-022526-j9kg00qf 3248 6 agent agent NN cord-022526-j9kg00qf 3248 7 of of IN cord-022526-j9kg00qf 3248 8 DPJ dpj NN cord-022526-j9kg00qf 3248 9 , , , cord-022526-j9kg00qf 3248 10 penicillin penicillin NN cord-022526-j9kg00qf 3248 11 often often RB cord-022526-j9kg00qf 3248 12 is be VBZ cord-022526-j9kg00qf 3248 13 administered administer VBN cord-022526-j9kg00qf 3248 14 to to IN cord-022526-j9kg00qf 3248 15 affected affect VBN cord-022526-j9kg00qf 3248 16 horses horse NNS cord-022526-j9kg00qf 3248 17 . . . cord-022526-j9kg00qf 3249 1 However however RB cord-022526-j9kg00qf 3249 2 , , , cord-022526-j9kg00qf 3249 3 one one PRP cord-022526-j9kg00qf 3249 4 should should MD cord-022526-j9kg00qf 3249 5 consider consider VB cord-022526-j9kg00qf 3249 6 broad broad JJ cord-022526-j9kg00qf 3249 7 - - HYPH cord-022526-j9kg00qf 3249 8 spectrum spectrum NN cord-022526-j9kg00qf 3249 9 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 3249 10 coverage coverage NN cord-022526-j9kg00qf 3249 11 for for IN cord-022526-j9kg00qf 3249 12 horses horse NNS cord-022526-j9kg00qf 3249 13 with with IN cord-022526-j9kg00qf 3249 14 DPJ dpj NN cord-022526-j9kg00qf 3249 15 . . . cord-022526-j9kg00qf 3250 1 One one PRP cord-022526-j9kg00qf 3250 2 can can MD cord-022526-j9kg00qf 3250 3 add add VB cord-022526-j9kg00qf 3250 4 an an DT cord-022526-j9kg00qf 3250 5 aminoglycoside aminoglycoside NN cord-022526-j9kg00qf 3250 6 ( ( -LRB- cord-022526-j9kg00qf 3250 7 gentamicin gentamicin NN cord-022526-j9kg00qf 3250 8 , , , cord-022526-j9kg00qf 3250 9 amikacin amikacin NNP cord-022526-j9kg00qf 3250 10 ) ) -RRB- cord-022526-j9kg00qf 3250 11 or or CC cord-022526-j9kg00qf 3250 12 thirdgeneration thirdgeneration NNP cord-022526-j9kg00qf 3250 13 cephalosporin cephalosporin NNP cord-022526-j9kg00qf 3250 14 ( ( -LRB- cord-022526-j9kg00qf 3250 15 ceftiofur ceftiofur JJ cord-022526-j9kg00qf 3250 16 [ [ -LRB- cord-022526-j9kg00qf 3250 17 Naxcel Naxcel NNP cord-022526-j9kg00qf 3250 18 ] ] -RRB- cord-022526-j9kg00qf 3250 19 , , , cord-022526-j9kg00qf 3250 20 Upjohn Upjohn NNP cord-022526-j9kg00qf 3250 21 Co. Co. NNP cord-022526-j9kg00qf 3250 22 , , , cord-022526-j9kg00qf 3250 23 Kalamazoo Kalamazoo NNP cord-022526-j9kg00qf 3250 24 , , , cord-022526-j9kg00qf 3250 25 Michigan Michigan NNP cord-022526-j9kg00qf 3250 26 ) ) -RRB- cord-022526-j9kg00qf 3250 27 to to IN cord-022526-j9kg00qf 3250 28 the the DT cord-022526-j9kg00qf 3250 29 penicillin penicillin NN cord-022526-j9kg00qf 3250 30 therapy therapy NN cord-022526-j9kg00qf 3250 31 , , , cord-022526-j9kg00qf 3250 32 keeping keep VBG cord-022526-j9kg00qf 3250 33 in in IN cord-022526-j9kg00qf 3250 34 mind mind NN cord-022526-j9kg00qf 3250 35 the the DT cord-022526-j9kg00qf 3250 36 potential potential JJ cord-022526-j9kg00qf 3250 37 adverse adverse JJ cord-022526-j9kg00qf 3250 38 effects effect NNS cord-022526-j9kg00qf 3250 39 of of IN cord-022526-j9kg00qf 3250 40 these these DT cord-022526-j9kg00qf 3250 41 drugs drug NNS cord-022526-j9kg00qf 3250 42 on on IN cord-022526-j9kg00qf 3250 43 renal renal JJ cord-022526-j9kg00qf 3250 44 function function NN cord-022526-j9kg00qf 3250 45 . . . cord-022526-j9kg00qf 3251 1 Effective effective JJ cord-022526-j9kg00qf 3251 2 antisecretory antisecretory NN cord-022526-j9kg00qf 3251 3 medications medication NNS cord-022526-j9kg00qf 3251 4 targeting target VBG cord-022526-j9kg00qf 3251 5 the the DT cord-022526-j9kg00qf 3251 6 equine equine JJ cord-022526-j9kg00qf 3251 7 small small JJ cord-022526-j9kg00qf 3251 8 intestine intestine NN cord-022526-j9kg00qf 3251 9 have have VBP cord-022526-j9kg00qf 3251 10 not not RB cord-022526-j9kg00qf 3251 11 been be VBN cord-022526-j9kg00qf 3251 12 identified identify VBN cord-022526-j9kg00qf 3251 13 . . . cord-022526-j9kg00qf 3252 1 One one PRP cord-022526-j9kg00qf 3252 2 should should MD cord-022526-j9kg00qf 3252 3 consider consider VB cord-022526-j9kg00qf 3252 4 the the DT cord-022526-j9kg00qf 3252 5 nutritional nutritional JJ cord-022526-j9kg00qf 3252 6 needs need NNS cord-022526-j9kg00qf 3252 7 of of IN cord-022526-j9kg00qf 3252 8 horses horse NNS cord-022526-j9kg00qf 3252 9 with with IN cord-022526-j9kg00qf 3252 10 DPJ dpj NN cord-022526-j9kg00qf 3252 11 . . . cord-022526-j9kg00qf 3253 1 Most Most JJS cord-022526-j9kg00qf 3253 2 horses horse NNS cord-022526-j9kg00qf 3253 3 have have VBP cord-022526-j9kg00qf 3253 4 a a DT cord-022526-j9kg00qf 3253 5 total total JJ cord-022526-j9kg00qf 3253 6 body body NN cord-022526-j9kg00qf 3253 7 protein protein NN cord-022526-j9kg00qf 3253 8 loss loss NN cord-022526-j9kg00qf 3253 9 from from IN cord-022526-j9kg00qf 3253 10 cachexia cachexia NN cord-022526-j9kg00qf 3253 11 and and CC cord-022526-j9kg00qf 3253 12 a a DT cord-022526-j9kg00qf 3253 13 protein protein NN cord-022526-j9kg00qf 3253 14 - - HYPH cord-022526-j9kg00qf 3253 15 losing lose VBG cord-022526-j9kg00qf 3253 16 enteropathy enteropathy NNP cord-022526-j9kg00qf 3253 17 . . . cord-022526-j9kg00qf 3254 1 Total total JJ cord-022526-j9kg00qf 3254 2 parenteral parenteral JJ cord-022526-j9kg00qf 3254 3 nutrition nutrition NN cord-022526-j9kg00qf 3254 4 may may MD cord-022526-j9kg00qf 3254 5 be be VB cord-022526-j9kg00qf 3254 6 indicated indicate VBN cord-022526-j9kg00qf 3254 7 in in IN cord-022526-j9kg00qf 3254 8 horses horse NNS cord-022526-j9kg00qf 3254 9 that that WDT cord-022526-j9kg00qf 3254 10 remain remain VBP cord-022526-j9kg00qf 3254 11 anorectic anorectic JJ cord-022526-j9kg00qf 3254 12 for for IN cord-022526-j9kg00qf 3254 13 more more JJR cord-022526-j9kg00qf 3254 14 than than IN cord-022526-j9kg00qf 3254 15 3 3 CD cord-022526-j9kg00qf 3254 16 to to TO cord-022526-j9kg00qf 3254 17 4 4 CD cord-022526-j9kg00qf 3254 18 days day NNS cord-022526-j9kg00qf 3254 19 . . . cord-022526-j9kg00qf 3255 1 Parenterally parenterally RB cord-022526-j9kg00qf 3255 2 administered administer VBN cord-022526-j9kg00qf 3255 3 solutions solution NNS cord-022526-j9kg00qf 3255 4 containing contain VBG cord-022526-j9kg00qf 3255 5 glucose glucose NN cord-022526-j9kg00qf 3255 6 , , , cord-022526-j9kg00qf 3255 7 balanced balanced JJ cord-022526-j9kg00qf 3255 8 amino amino NN cord-022526-j9kg00qf 3255 9 acid acid NN cord-022526-j9kg00qf 3255 10 solutions solution NNS cord-022526-j9kg00qf 3255 11 , , , cord-022526-j9kg00qf 3255 12 lipid lipid NN cord-022526-j9kg00qf 3255 13 emulsions emulsion NNS cord-022526-j9kg00qf 3255 14 , , , cord-022526-j9kg00qf 3255 15 balanced balanced JJ cord-022526-j9kg00qf 3255 16 electrolyte electrolyte NN cord-022526-j9kg00qf 3255 17 and and CC cord-022526-j9kg00qf 3255 18 trace trace NN cord-022526-j9kg00qf 3255 19 minerals mineral NNS cord-022526-j9kg00qf 3255 20 , , , cord-022526-j9kg00qf 3255 21 and and CC cord-022526-j9kg00qf 3255 22 vitamins vitamin NNS cord-022526-j9kg00qf 3255 23 have have VBP cord-022526-j9kg00qf 3255 24 been be VBN cord-022526-j9kg00qf 3255 25 administered administer VBN cord-022526-j9kg00qf 3255 26 to to IN cord-022526-j9kg00qf 3255 27 adult adult NN cord-022526-j9kg00qf 3255 28 horses horse NNS cord-022526-j9kg00qf 3255 29 with with IN cord-022526-j9kg00qf 3255 30 small small JJ cord-022526-j9kg00qf 3255 31 intestinal intestinal JJ cord-022526-j9kg00qf 3255 32 ileus ileus NN cord-022526-j9kg00qf 3255 33 or or CC cord-022526-j9kg00qf 3255 34 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3255 35 . . . cord-022526-j9kg00qf 3256 1 Based base VBN cord-022526-j9kg00qf 3256 2 on on IN cord-022526-j9kg00qf 3256 3 a a DT cord-022526-j9kg00qf 3256 4 small small JJ cord-022526-j9kg00qf 3256 5 number number NN cord-022526-j9kg00qf 3256 6 of of IN cord-022526-j9kg00qf 3256 7 horses horse NNS cord-022526-j9kg00qf 3256 8 , , , cord-022526-j9kg00qf 3256 9 this this DT cord-022526-j9kg00qf 3256 10 therapy therapy NN cord-022526-j9kg00qf 3256 11 has have VBZ cord-022526-j9kg00qf 3256 12 proved prove VBN cord-022526-j9kg00qf 3256 13 promising promising JJ cord-022526-j9kg00qf 3256 14 in in IN cord-022526-j9kg00qf 3256 15 terms term NNS cord-022526-j9kg00qf 3256 16 of of IN cord-022526-j9kg00qf 3256 17 minimizing minimize VBG cord-022526-j9kg00qf 3256 18 protein protein NN cord-022526-j9kg00qf 3256 19 losses loss NNS cord-022526-j9kg00qf 3256 20 and and CC cord-022526-j9kg00qf 3256 21 decreasing decrease VBG cord-022526-j9kg00qf 3256 22 the the DT cord-022526-j9kg00qf 3256 23 duration duration NN cord-022526-j9kg00qf 3256 24 of of IN cord-022526-j9kg00qf 3256 25 illness illness NN cord-022526-j9kg00qf 3256 26 . . . cord-022526-j9kg00qf 3257 1 Providing provide VBG cord-022526-j9kg00qf 3257 2 for for IN cord-022526-j9kg00qf 3257 3 part part NN cord-022526-j9kg00qf 3257 4 of of IN cord-022526-j9kg00qf 3257 5 the the DT cord-022526-j9kg00qf 3257 6 nutritional nutritional JJ cord-022526-j9kg00qf 3257 7 requirements requirement NNS cord-022526-j9kg00qf 3257 8 of of IN cord-022526-j9kg00qf 3257 9 the the DT cord-022526-j9kg00qf 3257 10 horse horse NN cord-022526-j9kg00qf 3257 11 ( ( -LRB- cord-022526-j9kg00qf 3257 12 8000 8000 CD cord-022526-j9kg00qf 3257 13 to to IN cord-022526-j9kg00qf 3257 14 12,000 12,000 CD cord-022526-j9kg00qf 3257 15 kcal kcal NNP cord-022526-j9kg00qf 3257 16 / / SYM cord-022526-j9kg00qf 3257 17 day day NN cord-022526-j9kg00qf 3257 18 ) ) -RRB- cord-022526-j9kg00qf 3257 19 is be VBZ cord-022526-j9kg00qf 3257 20 possible possible JJ cord-022526-j9kg00qf 3257 21 with with IN cord-022526-j9kg00qf 3257 22 glucose glucose NN cord-022526-j9kg00qf 3257 23 - - HYPH cord-022526-j9kg00qf 3257 24 amino amino NN cord-022526-j9kg00qf 3257 25 acid acid NN cord-022526-j9kg00qf 3257 26 solutions solution NNS cord-022526-j9kg00qf 3257 27 , , , cord-022526-j9kg00qf 3257 28 which which WDT cord-022526-j9kg00qf 3257 29 are be VBP cord-022526-j9kg00qf 3257 30 of of IN cord-022526-j9kg00qf 3257 31 moderate moderate JJ cord-022526-j9kg00qf 3257 32 cost cost NN cord-022526-j9kg00qf 3257 33 . . . cord-022526-j9kg00qf 3258 1 One one CD cord-022526-j9kg00qf 3258 2 may may MD cord-022526-j9kg00qf 3258 3 suppose suppose VB cord-022526-j9kg00qf 3258 4 reasonably reasonably RB cord-022526-j9kg00qf 3258 5 that that IN cord-022526-j9kg00qf 3258 6 providing provide VBG cord-022526-j9kg00qf 3258 7 nutritional nutritional JJ cord-022526-j9kg00qf 3258 8 support support NN cord-022526-j9kg00qf 3258 9 to to IN cord-022526-j9kg00qf 3258 10 an an DT cord-022526-j9kg00qf 3258 11 anorectic anorectic JJ cord-022526-j9kg00qf 3258 12 , , , cord-022526-j9kg00qf 3258 13 severely severely RB cord-022526-j9kg00qf 3258 14 ill ill JJ cord-022526-j9kg00qf 3258 15 horse horse NN cord-022526-j9kg00qf 3258 16 will will MD cord-022526-j9kg00qf 3258 17 facilitate facilitate VB cord-022526-j9kg00qf 3258 18 the the DT cord-022526-j9kg00qf 3258 19 healing healing NN cord-022526-j9kg00qf 3258 20 process process NN cord-022526-j9kg00qf 3258 21 and and CC cord-022526-j9kg00qf 3258 22 even even RB cord-022526-j9kg00qf 3258 23 shorten shorten VB cord-022526-j9kg00qf 3258 24 the the DT cord-022526-j9kg00qf 3258 25 duration duration NN cord-022526-j9kg00qf 3258 26 of of IN cord-022526-j9kg00qf 3258 27 illness illness NN cord-022526-j9kg00qf 3258 28 . . . cord-022526-j9kg00qf 3259 1 Thus thus RB cord-022526-j9kg00qf 3259 2 the the DT cord-022526-j9kg00qf 3259 3 overall overall JJ cord-022526-j9kg00qf 3259 4 cost cost NN cord-022526-j9kg00qf 3259 5 of of IN cord-022526-j9kg00qf 3259 6 providing provide VBG cord-022526-j9kg00qf 3259 7 parenteral parenteral JJ cord-022526-j9kg00qf 3259 8 nutritional nutritional JJ cord-022526-j9kg00qf 3259 9 supplementation supplementation NN cord-022526-j9kg00qf 3259 10 to to IN cord-022526-j9kg00qf 3259 11 horses horse NNS cord-022526-j9kg00qf 3259 12 with with IN cord-022526-j9kg00qf 3259 13 DPJ dpj NN cord-022526-j9kg00qf 3259 14 may may MD cord-022526-j9kg00qf 3259 15 well well RB cord-022526-j9kg00qf 3259 16 be be VB cord-022526-j9kg00qf 3259 17 offset offset VBN cord-022526-j9kg00qf 3259 18 by by IN cord-022526-j9kg00qf 3259 19 quicker quick JJR cord-022526-j9kg00qf 3259 20 recovery recovery NN cord-022526-j9kg00qf 3259 21 and and CC cord-022526-j9kg00qf 3259 22 diminished diminished JJ cord-022526-j9kg00qf 3259 23 requirements requirement NNS cord-022526-j9kg00qf 3259 24 for for IN cord-022526-j9kg00qf 3259 25 other other JJ cord-022526-j9kg00qf 3259 26 , , , cord-022526-j9kg00qf 3259 27 expensive expensive JJ cord-022526-j9kg00qf 3259 28 treatments treatment NNS cord-022526-j9kg00qf 3259 29 . . . cord-022526-j9kg00qf 3260 1 Normal normal JJ cord-022526-j9kg00qf 3260 2 ( ( -LRB- cord-022526-j9kg00qf 3260 3 healthy healthy JJ cord-022526-j9kg00qf 3260 4 ) ) -RRB- cord-022526-j9kg00qf 3260 5 intestine intestine NN cord-022526-j9kg00qf 3260 6 is be VBZ cord-022526-j9kg00qf 3260 7 necessary necessary JJ cord-022526-j9kg00qf 3260 8 for for IN cord-022526-j9kg00qf 3260 9 optimum optimum JJ cord-022526-j9kg00qf 3260 10 performance performance NN cord-022526-j9kg00qf 3260 11 of of IN cord-022526-j9kg00qf 3260 12 prokinetic prokinetic JJ cord-022526-j9kg00qf 3260 13 agents agent NNS cord-022526-j9kg00qf 3260 14 in in IN cord-022526-j9kg00qf 3260 15 horses horse NNS cord-022526-j9kg00qf 3260 16 . . . cord-022526-j9kg00qf 3261 1 Many many JJ cord-022526-j9kg00qf 3261 2 motilitymodifying motilitymodifye VBG cord-022526-j9kg00qf 3261 3 agents agent NNS cord-022526-j9kg00qf 3261 4 likely likely RB cord-022526-j9kg00qf 3261 5 are be VBP cord-022526-j9kg00qf 3261 6 ineffective ineffective JJ cord-022526-j9kg00qf 3261 7 in in IN cord-022526-j9kg00qf 3261 8 cases case NNS cord-022526-j9kg00qf 3261 9 of of IN cord-022526-j9kg00qf 3261 10 DPJ dpj NN cord-022526-j9kg00qf 3261 11 . . . cord-022526-j9kg00qf 3262 1 However however RB cord-022526-j9kg00qf 3262 2 , , , cord-022526-j9kg00qf 3262 3 some some DT cord-022526-j9kg00qf 3262 4 benefit benefit NN cord-022526-j9kg00qf 3262 5 may may MD cord-022526-j9kg00qf 3262 6 come come VB cord-022526-j9kg00qf 3262 7 of of IN cord-022526-j9kg00qf 3262 8 the the DT cord-022526-j9kg00qf 3262 9 judicious judicious JJ cord-022526-j9kg00qf 3262 10 use use NN cord-022526-j9kg00qf 3262 11 of of IN cord-022526-j9kg00qf 3262 12 prokinetic prokinetic JJ cord-022526-j9kg00qf 3262 13 agents agent NNS cord-022526-j9kg00qf 3262 14 in in IN cord-022526-j9kg00qf 3262 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 3262 16 conditions condition NNS cord-022526-j9kg00qf 3262 17 of of IN cord-022526-j9kg00qf 3262 18 the the DT cord-022526-j9kg00qf 3262 19 equine equine JJ cord-022526-j9kg00qf 3262 20 intestine intestine NN cord-022526-j9kg00qf 3262 21 , , , cord-022526-j9kg00qf 3262 22 particularly particularly RB cord-022526-j9kg00qf 3262 23 if if IN cord-022526-j9kg00qf 3262 24 the the DT cord-022526-j9kg00qf 3262 25 agent agent NN cord-022526-j9kg00qf 3262 26 provides provide VBZ cord-022526-j9kg00qf 3262 27 additional additional JJ cord-022526-j9kg00qf 3262 28 effects effect NNS cord-022526-j9kg00qf 3262 29 such such JJ cord-022526-j9kg00qf 3262 30 as as IN cord-022526-j9kg00qf 3262 31 analgesia analgesia NN cord-022526-j9kg00qf 3262 32 . . . cord-022526-j9kg00qf 3263 1 For for IN cord-022526-j9kg00qf 3263 2 example example NN cord-022526-j9kg00qf 3263 3 , , , cord-022526-j9kg00qf 3263 4 lidocaine lidocaine NN cord-022526-j9kg00qf 3263 5 infusion infusion NN cord-022526-j9kg00qf 3263 6 has have VBZ cord-022526-j9kg00qf 3263 7 several several JJ cord-022526-j9kg00qf 3263 8 actions action NNS cord-022526-j9kg00qf 3263 9 that that WDT cord-022526-j9kg00qf 3263 10 may may MD cord-022526-j9kg00qf 3263 11 be be VB cord-022526-j9kg00qf 3263 12 beneficial beneficial JJ cord-022526-j9kg00qf 3263 13 in in IN cord-022526-j9kg00qf 3263 14 the the DT cord-022526-j9kg00qf 3263 15 treatment treatment NN cord-022526-j9kg00qf 3263 16 of of IN cord-022526-j9kg00qf 3263 17 ileus ileus NNP cord-022526-j9kg00qf 3263 18 , , , cord-022526-j9kg00qf 3263 19 including include VBG cord-022526-j9kg00qf 3263 20 suppression suppression NN cord-022526-j9kg00qf 3263 21 of of IN cord-022526-j9kg00qf 3263 22 primary primary JJ cord-022526-j9kg00qf 3263 23 afferent afferent NN cord-022526-j9kg00qf 3263 24 firing firing NN cord-022526-j9kg00qf 3263 25 , , , cord-022526-j9kg00qf 3263 26 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3263 27 properties property NNS cord-022526-j9kg00qf 3263 28 , , , cord-022526-j9kg00qf 3263 29 an an DT cord-022526-j9kg00qf 3263 30 observed observed JJ cord-022526-j9kg00qf 3263 31 analgesic analgesic JJ cord-022526-j9kg00qf 3263 32 effect effect NN cord-022526-j9kg00qf 3263 33 , , , cord-022526-j9kg00qf 3263 34 and and CC cord-022526-j9kg00qf 3263 35 direct direct JJ cord-022526-j9kg00qf 3263 36 stimulation stimulation NN cord-022526-j9kg00qf 3263 37 of of IN cord-022526-j9kg00qf 3263 38 smooth smooth JJ cord-022526-j9kg00qf 3263 39 muscle muscle NN cord-022526-j9kg00qf 3263 40 . . . cord-022526-j9kg00qf 3264 1 9 9 CD cord-022526-j9kg00qf 3265 1 An an DT cord-022526-j9kg00qf 3265 2 infusion infusion NN cord-022526-j9kg00qf 3265 3 dose dose NN cord-022526-j9kg00qf 3265 4 of of IN cord-022526-j9kg00qf 3265 5 15 15 CD cord-022526-j9kg00qf 3265 6 to to TO cord-022526-j9kg00qf 3265 7 20 20 CD cord-022526-j9kg00qf 3265 8 mg mg NNP cord-022526-j9kg00qf 3265 9 / / SYM cord-022526-j9kg00qf 3265 10 min min NN cord-022526-j9kg00qf 3265 11 over over IN cord-022526-j9kg00qf 3265 12 5 5 CD cord-022526-j9kg00qf 3265 13 to to TO cord-022526-j9kg00qf 3265 14 6 6 CD cord-022526-j9kg00qf 3265 15 hours hour NNS cord-022526-j9kg00qf 3265 16 has have VBZ cord-022526-j9kg00qf 3265 17 been be VBN cord-022526-j9kg00qf 3265 18 recommended recommend VBN cord-022526-j9kg00qf 3265 19 . . . cord-022526-j9kg00qf 3266 1 The the DT cord-022526-j9kg00qf 3266 2 reader reader NN cord-022526-j9kg00qf 3266 3 is be VBZ cord-022526-j9kg00qf 3266 4 referred refer VBN cord-022526-j9kg00qf 3266 5 to to IN cord-022526-j9kg00qf 3266 6 Chapters chapter NNS cord-022526-j9kg00qf 3266 7 13.6 13.6 CD cord-022526-j9kg00qf 3266 8 and and CC cord-022526-j9kg00qf 3266 9 13.15 13.15 CD cord-022526-j9kg00qf 3266 10 for for IN cord-022526-j9kg00qf 3266 11 a a DT cord-022526-j9kg00qf 3266 12 complete complete JJ cord-022526-j9kg00qf 3266 13 description description NN cord-022526-j9kg00qf 3266 14 of of IN cord-022526-j9kg00qf 3266 15 motility motility NN cord-022526-j9kg00qf 3266 16 modifying modify VBG cord-022526-j9kg00qf 3266 17 agents agent NNS cord-022526-j9kg00qf 3266 18 . . . cord-022526-j9kg00qf 3267 1 Medical medical JJ cord-022526-j9kg00qf 3267 2 therapy therapy NN cord-022526-j9kg00qf 3267 3 is be VBZ cord-022526-j9kg00qf 3267 4 sufficient sufficient JJ cord-022526-j9kg00qf 3267 5 in in IN cord-022526-j9kg00qf 3267 6 most most JJS cord-022526-j9kg00qf 3267 7 cases case NNS cord-022526-j9kg00qf 3267 8 of of IN cord-022526-j9kg00qf 3267 9 DPJ dpj NN cord-022526-j9kg00qf 3267 10 , , , cord-022526-j9kg00qf 3267 11 but but CC cord-022526-j9kg00qf 3267 12 in in IN cord-022526-j9kg00qf 3267 13 those those DT cord-022526-j9kg00qf 3267 14 cases case NNS cord-022526-j9kg00qf 3267 15 in in IN cord-022526-j9kg00qf 3267 16 which which WDT cord-022526-j9kg00qf 3267 17 the the DT cord-022526-j9kg00qf 3267 18 horse horse NN cord-022526-j9kg00qf 3267 19 continues continue VBZ cord-022526-j9kg00qf 3267 20 to to TO cord-022526-j9kg00qf 3267 21 produce produce VB cord-022526-j9kg00qf 3267 22 copious copious JJ cord-022526-j9kg00qf 3267 23 enterogastric enterogastric JJ cord-022526-j9kg00qf 3267 24 reflux reflux NN cord-022526-j9kg00qf 3267 25 , , , cord-022526-j9kg00qf 3267 26 one one PRP cord-022526-j9kg00qf 3267 27 may may MD cord-022526-j9kg00qf 3267 28 consider consider VB cord-022526-j9kg00qf 3267 29 surgery surgery NN cord-022526-j9kg00qf 3267 30 as as IN cord-022526-j9kg00qf 3267 31 an an DT cord-022526-j9kg00qf 3267 32 option option NN cord-022526-j9kg00qf 3267 33 . . . cord-022526-j9kg00qf 3268 1 Refractory refractory JJ cord-022526-j9kg00qf 3268 2 cases case NNS cord-022526-j9kg00qf 3268 3 have have VBP cord-022526-j9kg00qf 3268 4 been be VBN cord-022526-j9kg00qf 3268 5 observed observe VBN cord-022526-j9kg00qf 3268 6 to to TO cord-022526-j9kg00qf 3268 7 improve improve VB cord-022526-j9kg00qf 3268 8 with with IN cord-022526-j9kg00qf 3268 9 surgical surgical JJ cord-022526-j9kg00qf 3268 10 intervention intervention NN cord-022526-j9kg00qf 3268 11 ; ; : cord-022526-j9kg00qf 3268 12 however however RB cord-022526-j9kg00qf 3268 13 , , , cord-022526-j9kg00qf 3268 14 some some DT cord-022526-j9kg00qf 3268 15 horses horse NNS cord-022526-j9kg00qf 3268 16 with with IN cord-022526-j9kg00qf 3268 17 refractory refractory JJ cord-022526-j9kg00qf 3268 18 DPJ DPJ NNP cord-022526-j9kg00qf 3268 19 have have VBP cord-022526-j9kg00qf 3268 20 been be VBN cord-022526-j9kg00qf 3268 21 observed observe VBN cord-022526-j9kg00qf 3268 22 to to TO cord-022526-j9kg00qf 3268 23 recover recover VB cord-022526-j9kg00qf 3268 24 with with IN cord-022526-j9kg00qf 3268 25 supportive supportive JJ cord-022526-j9kg00qf 3268 26 medical medical JJ cord-022526-j9kg00qf 3268 27 care care NN cord-022526-j9kg00qf 3268 28 alone alone RB cord-022526-j9kg00qf 3268 29 even even RB cord-022526-j9kg00qf 3268 30 after after IN cord-022526-j9kg00qf 3268 31 20 20 CD cord-022526-j9kg00qf 3268 32 days day NNS cord-022526-j9kg00qf 3268 33 of of IN cord-022526-j9kg00qf 3268 34 refluxing refluxe VBG cord-022526-j9kg00qf 3268 35 large large JJ cord-022526-j9kg00qf 3268 36 amounts amount NNS cord-022526-j9kg00qf 3268 37 of of IN cord-022526-j9kg00qf 3268 38 fluid fluid NN cord-022526-j9kg00qf 3268 39 every every DT cord-022526-j9kg00qf 3268 40 2 2 CD cord-022526-j9kg00qf 3268 41 to to TO cord-022526-j9kg00qf 3268 42 4 4 CD cord-022526-j9kg00qf 3268 43 hours hour NNS cord-022526-j9kg00qf 3268 44 ( ( -LRB- cord-022526-j9kg00qf 3268 45 personal personal JJ cord-022526-j9kg00qf 3268 46 observation observation NN cord-022526-j9kg00qf 3268 47 ) ) -RRB- cord-022526-j9kg00qf 3268 48 . . . cord-022526-j9kg00qf 3269 1 The the DT cord-022526-j9kg00qf 3269 2 decision decision NN cord-022526-j9kg00qf 3269 3 of of IN cord-022526-j9kg00qf 3269 4 when when WRB cord-022526-j9kg00qf 3269 5 to to TO cord-022526-j9kg00qf 3269 6 intervene intervene VB cord-022526-j9kg00qf 3269 7 surgically surgically RB cord-022526-j9kg00qf 3269 8 often often RB cord-022526-j9kg00qf 3269 9 is be VBZ cord-022526-j9kg00qf 3269 10 difficult difficult JJ cord-022526-j9kg00qf 3269 11 . . . cord-022526-j9kg00qf 3270 1 One one CD cord-022526-j9kg00qf 3270 2 may may MD cord-022526-j9kg00qf 3270 3 elect elect VB cord-022526-j9kg00qf 3270 4 surgery surgery NN cord-022526-j9kg00qf 3270 5 to to TO cord-022526-j9kg00qf 3270 6 determine determine VB cord-022526-j9kg00qf 3270 7 the the DT cord-022526-j9kg00qf 3270 8 extent extent NN cord-022526-j9kg00qf 3270 9 of of IN cord-022526-j9kg00qf 3270 10 gross gross JJ cord-022526-j9kg00qf 3270 11 pathologic pathologic JJ cord-022526-j9kg00qf 3270 12 condition condition NN cord-022526-j9kg00qf 3270 13 and and CC cord-022526-j9kg00qf 3270 14 intestinal intestinal JJ cord-022526-j9kg00qf 3270 15 distention distention NN cord-022526-j9kg00qf 3270 16 and and CC cord-022526-j9kg00qf 3270 17 to to TO cord-022526-j9kg00qf 3270 18 perform perform VB cord-022526-j9kg00qf 3270 19 intestinal intestinal JJ cord-022526-j9kg00qf 3270 20 bypass bypass NN cord-022526-j9kg00qf 3270 21 so so IN cord-022526-j9kg00qf 3270 22 as as IN cord-022526-j9kg00qf 3270 23 to to TO cord-022526-j9kg00qf 3270 24 direct direct VB cord-022526-j9kg00qf 3270 25 enterogastric enterogastric JJ cord-022526-j9kg00qf 3270 26 reflux reflux NN cord-022526-j9kg00qf 3270 27 toward toward IN cord-022526-j9kg00qf 3270 28 the the DT cord-022526-j9kg00qf 3270 29 cecum cecum NN cord-022526-j9kg00qf 3270 30 and and CC cord-022526-j9kg00qf 3270 31 colon colon NN cord-022526-j9kg00qf 3270 32 , , , cord-022526-j9kg00qf 3270 33 where where WRB cord-022526-j9kg00qf 3270 34 the the DT cord-022526-j9kg00qf 3270 35 fluid fluid NN cord-022526-j9kg00qf 3270 36 can can MD cord-022526-j9kg00qf 3270 37 be be VB cord-022526-j9kg00qf 3270 38 reabsorbed reabsorb VBN cord-022526-j9kg00qf 3270 39 . . . cord-022526-j9kg00qf 3271 1 Allen Allen NNP cord-022526-j9kg00qf 3271 2 and and CC cord-022526-j9kg00qf 3271 3 Clark Clark NNP cord-022526-j9kg00qf 3271 4 5 5 CD cord-022526-j9kg00qf 3271 5 have have VBP cord-022526-j9kg00qf 3271 6 described describe VBN cord-022526-j9kg00qf 3271 7 two two CD cord-022526-j9kg00qf 3271 8 approaches approach NNS cord-022526-j9kg00qf 3271 9 for for IN cord-022526-j9kg00qf 3271 10 surgical surgical JJ cord-022526-j9kg00qf 3271 11 therapy therapy NN cord-022526-j9kg00qf 3271 12 in in IN cord-022526-j9kg00qf 3271 13 such such JJ cord-022526-j9kg00qf 3271 14 cases case NNS cord-022526-j9kg00qf 3271 15 . . . cord-022526-j9kg00qf 3272 1 A a DT cord-022526-j9kg00qf 3272 2 standing stand VBG cord-022526-j9kg00qf 3272 3 right right RB cord-022526-j9kg00qf 3272 4 flank flank NN cord-022526-j9kg00qf 3272 5 laparotomy laparotomy NN cord-022526-j9kg00qf 3272 6 with with IN cord-022526-j9kg00qf 3272 7 resection resection NN cord-022526-j9kg00qf 3272 8 of of IN cord-022526-j9kg00qf 3272 9 the the DT cord-022526-j9kg00qf 3272 10 last last JJ cord-022526-j9kg00qf 3272 11 rib rib NN cord-022526-j9kg00qf 3272 12 has have VBZ cord-022526-j9kg00qf 3272 13 been be VBN cord-022526-j9kg00qf 3272 14 used use VBN cord-022526-j9kg00qf 3272 15 to to TO cord-022526-j9kg00qf 3272 16 approach approach VB cord-022526-j9kg00qf 3272 17 the the DT cord-022526-j9kg00qf 3272 18 duodenum duodenum NN cord-022526-j9kg00qf 3272 19 and and CC cord-022526-j9kg00qf 3272 20 cecal cecal JJ cord-022526-j9kg00qf 3272 21 base base NN cord-022526-j9kg00qf 3272 22 . . . cord-022526-j9kg00qf 3273 1 Using use VBG cord-022526-j9kg00qf 3273 2 this this DT cord-022526-j9kg00qf 3273 3 approach approach NN cord-022526-j9kg00qf 3273 4 , , , cord-022526-j9kg00qf 3273 5 one one PRP cord-022526-j9kg00qf 3273 6 makes make VBZ cord-022526-j9kg00qf 3273 7 a a DT cord-022526-j9kg00qf 3273 8 small small JJ cord-022526-j9kg00qf 3273 9 stoma stoma NN cord-022526-j9kg00qf 3273 10 between between IN cord-022526-j9kg00qf 3273 11 the the DT cord-022526-j9kg00qf 3273 12 duodenum duodenum NN cord-022526-j9kg00qf 3273 13 and and CC cord-022526-j9kg00qf 3273 14 cecum cecum NN cord-022526-j9kg00qf 3273 15 using use VBG cord-022526-j9kg00qf 3273 16 a a DT cord-022526-j9kg00qf 3273 17 handsewn handsewn JJ cord-022526-j9kg00qf 3273 18 1.0-to 1.0-to CD cord-022526-j9kg00qf 3273 19 1.5-cm 1.5-cm CD cord-022526-j9kg00qf 3273 20 side side NN cord-022526-j9kg00qf 3273 21 - - HYPH cord-022526-j9kg00qf 3273 22 to to IN cord-022526-j9kg00qf 3273 23 - - HYPH cord-022526-j9kg00qf 3273 24 side side NN cord-022526-j9kg00qf 3273 25 anastomosis anastomosis NN cord-022526-j9kg00qf 3273 26 . . . cord-022526-j9kg00qf 3274 1 The the DT cord-022526-j9kg00qf 3274 2 stoma stoma NN cord-022526-j9kg00qf 3274 3 may may MD cord-022526-j9kg00qf 3274 4 act act VB cord-022526-j9kg00qf 3274 5 as as IN cord-022526-j9kg00qf 3274 6 a a DT cord-022526-j9kg00qf 3274 7 shunt shunt NN cord-022526-j9kg00qf 3274 8 to to TO cord-022526-j9kg00qf 3274 9 decompress decompress VB cord-022526-j9kg00qf 3274 10 the the DT cord-022526-j9kg00qf 3274 11 proximal proximal JJ cord-022526-j9kg00qf 3274 12 small small JJ cord-022526-j9kg00qf 3274 13 intestine intestine NN cord-022526-j9kg00qf 3274 14 and and CC cord-022526-j9kg00qf 3274 15 deliver deliver VB cord-022526-j9kg00qf 3274 16 the the DT cord-022526-j9kg00qf 3274 17 small small JJ cord-022526-j9kg00qf 3274 18 intestinal intestinal JJ cord-022526-j9kg00qf 3274 19 fluid fluid NN cord-022526-j9kg00qf 3274 20 to to IN cord-022526-j9kg00qf 3274 21 the the DT cord-022526-j9kg00qf 3274 22 cecum cecum NN cord-022526-j9kg00qf 3274 23 for for IN cord-022526-j9kg00qf 3274 24 reabsorption reabsorption NN cord-022526-j9kg00qf 3274 25 . . . cord-022526-j9kg00qf 3275 1 Following follow VBG cord-022526-j9kg00qf 3275 2 recovery recovery NN cord-022526-j9kg00qf 3275 3 , , , cord-022526-j9kg00qf 3275 4 the the DT cord-022526-j9kg00qf 3275 5 stoma stoma NN cord-022526-j9kg00qf 3275 6 likely likely RB cord-022526-j9kg00qf 3275 7 will will MD cord-022526-j9kg00qf 3275 8 close close VB cord-022526-j9kg00qf 3275 9 . . . cord-022526-j9kg00qf 3276 1 When when WRB cord-022526-j9kg00qf 3276 2 a a DT cord-022526-j9kg00qf 3276 3 veterinarian veterinarian NN cord-022526-j9kg00qf 3276 4 is be VBZ cord-022526-j9kg00qf 3276 5 confronted confront VBN cord-022526-j9kg00qf 3276 6 with with IN cord-022526-j9kg00qf 3276 7 a a DT cord-022526-j9kg00qf 3276 8 horse horse NN cord-022526-j9kg00qf 3276 9 exhibiting exhibit VBG cord-022526-j9kg00qf 3276 10 abdominal abdominal JJ cord-022526-j9kg00qf 3276 11 discomfort discomfort NN cord-022526-j9kg00qf 3276 12 , , , cord-022526-j9kg00qf 3276 13 with with IN cord-022526-j9kg00qf 3276 14 small small JJ cord-022526-j9kg00qf 3276 15 intestinal intestinal JJ cord-022526-j9kg00qf 3276 16 distention distention NN cord-022526-j9kg00qf 3276 17 palpable palpable NN cord-022526-j9kg00qf 3276 18 per per IN cord-022526-j9kg00qf 3276 19 rectum rectum NN cord-022526-j9kg00qf 3276 20 , , , cord-022526-j9kg00qf 3276 21 and and CC cord-022526-j9kg00qf 3276 22 greater great JJR cord-022526-j9kg00qf 3276 23 than than IN cord-022526-j9kg00qf 3276 24 2 2 CD cord-022526-j9kg00qf 3276 25 L l NN cord-022526-j9kg00qf 3276 26 of of IN cord-022526-j9kg00qf 3276 27 gastric gastric JJ cord-022526-j9kg00qf 3276 28 reflux reflux NN cord-022526-j9kg00qf 3276 29 , , , cord-022526-j9kg00qf 3276 30 the the DT cord-022526-j9kg00qf 3276 31 veterinarian veterinarian NN cord-022526-j9kg00qf 3276 32 should should MD cord-022526-j9kg00qf 3276 33 recommend recommend VB cord-022526-j9kg00qf 3276 34 referral referral NN cord-022526-j9kg00qf 3276 35 of of IN cord-022526-j9kg00qf 3276 36 the the DT cord-022526-j9kg00qf 3276 37 horse horse NN cord-022526-j9kg00qf 3276 38 to to IN cord-022526-j9kg00qf 3276 39 a a DT cord-022526-j9kg00qf 3276 40 facility facility NN cord-022526-j9kg00qf 3276 41 capable capable JJ cord-022526-j9kg00qf 3276 42 of of IN cord-022526-j9kg00qf 3276 43 performing perform VBG cord-022526-j9kg00qf 3276 44 abdominal abdominal JJ cord-022526-j9kg00qf 3276 45 surgery surgery NN cord-022526-j9kg00qf 3276 46 . . . cord-022526-j9kg00qf 3277 1 The the DT cord-022526-j9kg00qf 3277 2 chance chance NN cord-022526-j9kg00qf 3277 3 that that IN cord-022526-j9kg00qf 3277 4 such such PDT cord-022526-j9kg00qf 3277 5 a a DT cord-022526-j9kg00qf 3277 6 horse horse NN cord-022526-j9kg00qf 3277 7 has have VBZ cord-022526-j9kg00qf 3277 8 an an DT cord-022526-j9kg00qf 3277 9 intestinal intestinal JJ cord-022526-j9kg00qf 3277 10 obstruction obstruction NN cord-022526-j9kg00qf 3277 11 is be VBZ cord-022526-j9kg00qf 3277 12 too too RB cord-022526-j9kg00qf 3277 13 great great JJ cord-022526-j9kg00qf 3277 14 to to TO cord-022526-j9kg00qf 3277 15 decide decide VB cord-022526-j9kg00qf 3277 16 to to TO cord-022526-j9kg00qf 3277 17 treat treat VB cord-022526-j9kg00qf 3277 18 it -PRON- PRP cord-022526-j9kg00qf 3277 19 as as IN cord-022526-j9kg00qf 3277 20 if if IN cord-022526-j9kg00qf 3277 21 it -PRON- PRP cord-022526-j9kg00qf 3277 22 may may MD cord-022526-j9kg00qf 3277 23 have have VB cord-022526-j9kg00qf 3277 24 DPJ dpj NN cord-022526-j9kg00qf 3277 25 . . . cord-022526-j9kg00qf 3278 1 Surgery surgery NN cord-022526-j9kg00qf 3278 2 on on IN cord-022526-j9kg00qf 3278 3 such such JJ cord-022526-j9kg00qf 3278 4 horses horse NNS cord-022526-j9kg00qf 3278 5 is be VBZ cord-022526-j9kg00qf 3278 6 not not RB cord-022526-j9kg00qf 3278 7 unusual unusual JJ cord-022526-j9kg00qf 3278 8 , , , cord-022526-j9kg00qf 3278 9 even even RB cord-022526-j9kg00qf 3278 10 though though IN cord-022526-j9kg00qf 3278 11 DPJ dpj NN cord-022526-j9kg00qf 3278 12 is be VBZ cord-022526-j9kg00qf 3278 13 possible possible JJ cord-022526-j9kg00qf 3278 14 , , , cord-022526-j9kg00qf 3278 15 to to TO cord-022526-j9kg00qf 3278 16 rule rule VB cord-022526-j9kg00qf 3278 17 out out RP cord-022526-j9kg00qf 3278 18 an an DT cord-022526-j9kg00qf 3278 19 obstruction obstruction NN cord-022526-j9kg00qf 3278 20 . . . cord-022526-j9kg00qf 3279 1 At at IN cord-022526-j9kg00qf 3279 2 present present NN cord-022526-j9kg00qf 3279 3 , , , cord-022526-j9kg00qf 3279 4 the the DT cord-022526-j9kg00qf 3279 5 survival survival NN cord-022526-j9kg00qf 3279 6 of of IN cord-022526-j9kg00qf 3279 7 horses horse NNS cord-022526-j9kg00qf 3279 8 with with IN cord-022526-j9kg00qf 3279 9 DPJ dpj NN cord-022526-j9kg00qf 3279 10 that that WDT cord-022526-j9kg00qf 3279 11 undergo undergo VBP cord-022526-j9kg00qf 3279 12 surgery surgery NN cord-022526-j9kg00qf 3279 13 is be VBZ cord-022526-j9kg00qf 3279 14 much much RB cord-022526-j9kg00qf 3279 15 greater great JJR cord-022526-j9kg00qf 3279 16 than than IN cord-022526-j9kg00qf 3279 17 previously previously RB cord-022526-j9kg00qf 3279 18 described describe VBN cord-022526-j9kg00qf 3279 19 , , , cord-022526-j9kg00qf 3279 20 and and CC cord-022526-j9kg00qf 3279 21 certainly certainly RB cord-022526-j9kg00qf 3279 22 greater great JJR cord-022526-j9kg00qf 3279 23 than than IN cord-022526-j9kg00qf 3279 24 that that DT cord-022526-j9kg00qf 3279 25 of of IN cord-022526-j9kg00qf 3279 26 horses horse NNS cord-022526-j9kg00qf 3279 27 with with IN cord-022526-j9kg00qf 3279 28 small small JJ cord-022526-j9kg00qf 3279 29 intestinal intestinal JJ cord-022526-j9kg00qf 3279 30 obstruction obstruction NN cord-022526-j9kg00qf 3279 31 that that WDT cord-022526-j9kg00qf 3279 32 do do VBP cord-022526-j9kg00qf 3279 33 not not RB cord-022526-j9kg00qf 3279 34 have have VB cord-022526-j9kg00qf 3279 35 surgery surgery NN cord-022526-j9kg00qf 3279 36 . . . cord-022526-j9kg00qf 3280 1 Horses horse NNS cord-022526-j9kg00qf 3280 2 with with IN cord-022526-j9kg00qf 3280 3 DPJ dpj NN cord-022526-j9kg00qf 3280 4 that that WDT cord-022526-j9kg00qf 3280 5 receive receive VBP cord-022526-j9kg00qf 3280 6 appropriate appropriate JJ cord-022526-j9kg00qf 3280 7 therapy therapy NN cord-022526-j9kg00qf 3280 8 have have VBP cord-022526-j9kg00qf 3280 9 a a DT cord-022526-j9kg00qf 3280 10 reasonably reasonably RB cord-022526-j9kg00qf 3280 11 good good JJ cord-022526-j9kg00qf 3280 12 chance chance NN cord-022526-j9kg00qf 3280 13 of of IN cord-022526-j9kg00qf 3280 14 making make VBG cord-022526-j9kg00qf 3280 15 a a DT cord-022526-j9kg00qf 3280 16 full full JJ cord-022526-j9kg00qf 3280 17 recovery recovery NN cord-022526-j9kg00qf 3280 18 . . . cord-022526-j9kg00qf 3281 1 Horses horse NNS cord-022526-j9kg00qf 3281 2 that that WDT cord-022526-j9kg00qf 3281 3 continue continue VBP cord-022526-j9kg00qf 3281 4 to to TO cord-022526-j9kg00qf 3281 5 have have VB cord-022526-j9kg00qf 3281 6 frequent frequent JJ cord-022526-j9kg00qf 3281 7 episodes episode NNS cord-022526-j9kg00qf 3281 8 of of IN cord-022526-j9kg00qf 3281 9 voluminous voluminous JJ cord-022526-j9kg00qf 3281 10 nasogastric nasogastric NN cord-022526-j9kg00qf 3281 11 reflux reflux NN cord-022526-j9kg00qf 3281 12 and and CC cord-022526-j9kg00qf 3281 13 systemic systemic JJ cord-022526-j9kg00qf 3281 14 signs sign NNS cord-022526-j9kg00qf 3281 15 of of IN cord-022526-j9kg00qf 3281 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3281 17 and and CC cord-022526-j9kg00qf 3281 18 septicemia septicemia NN cord-022526-j9kg00qf 3281 19 have have VBP cord-022526-j9kg00qf 3281 20 a a DT cord-022526-j9kg00qf 3281 21 poorer poor JJR cord-022526-j9kg00qf 3281 22 prognosis prognosis NN cord-022526-j9kg00qf 3281 23 for for IN cord-022526-j9kg00qf 3281 24 recovery recovery NN cord-022526-j9kg00qf 3281 25 . . . cord-022526-j9kg00qf 3282 1 Frequent frequent JJ cord-022526-j9kg00qf 3282 2 complications complication NNS cord-022526-j9kg00qf 3282 3 of of IN cord-022526-j9kg00qf 3282 4 DPJ dpj NN cord-022526-j9kg00qf 3282 5 include include VBP cord-022526-j9kg00qf 3282 6 laminitis laminitis NN cord-022526-j9kg00qf 3282 7 , , , cord-022526-j9kg00qf 3282 8 thrombophlebitis thrombophlebitis NNP cord-022526-j9kg00qf 3282 9 , , , cord-022526-j9kg00qf 3282 10 and and CC cord-022526-j9kg00qf 3282 11 weight weight NN cord-022526-j9kg00qf 3282 12 loss loss NN cord-022526-j9kg00qf 3282 13 . . . cord-022526-j9kg00qf 3283 1 The the DT cord-022526-j9kg00qf 3283 2 clinical clinical JJ cord-022526-j9kg00qf 3283 3 signs sign NNS cord-022526-j9kg00qf 3283 4 of of IN cord-022526-j9kg00qf 3283 5 chronic chronic JJ cord-022526-j9kg00qf 3283 6 wasting wasting NN cord-022526-j9kg00qf 3283 7 and and CC cord-022526-j9kg00qf 3283 8 poor poor JJ cord-022526-j9kg00qf 3283 9 body body NN cord-022526-j9kg00qf 3283 10 condition condition NN cord-022526-j9kg00qf 3283 11 , , , cord-022526-j9kg00qf 3283 12 although although IN cord-022526-j9kg00qf 3283 13 nonspecific nonspecific JJ cord-022526-j9kg00qf 3283 14 for for IN cord-022526-j9kg00qf 3283 15 a a DT cord-022526-j9kg00qf 3283 16 diagnosis diagnosis NN cord-022526-j9kg00qf 3283 17 of of IN cord-022526-j9kg00qf 3283 18 malabsorption malabsorption NN cord-022526-j9kg00qf 3283 19 antemortem antemortem NNP cord-022526-j9kg00qf 3283 20 , , , cord-022526-j9kg00qf 3283 21 can can MD cord-022526-j9kg00qf 3283 22 be be VB cord-022526-j9kg00qf 3283 23 attributed attribute VBN cord-022526-j9kg00qf 3283 24 to to IN cord-022526-j9kg00qf 3283 25 proliferative proliferative JJ cord-022526-j9kg00qf 3283 26 or or CC cord-022526-j9kg00qf 3283 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 3283 28 intestinal intestinal JJ cord-022526-j9kg00qf 3283 29 disorders disorder NNS cord-022526-j9kg00qf 3283 30 , , , cord-022526-j9kg00qf 3283 31 often often RB cord-022526-j9kg00qf 3283 32 collectively collectively RB cord-022526-j9kg00qf 3283 33 referred refer VBN cord-022526-j9kg00qf 3283 34 to to IN cord-022526-j9kg00qf 3283 35 as as RB cord-022526-j9kg00qf 3283 36 chronic chronic JJ cord-022526-j9kg00qf 3283 37 inflammatory inflammatory JJ cord-022526-j9kg00qf 3283 38 bowel bowel NN cord-022526-j9kg00qf 3283 39 diseases disease NNS cord-022526-j9kg00qf 3283 40 . . . cord-022526-j9kg00qf 3284 1 1 1 LS cord-022526-j9kg00qf 3284 2 Clinical clinical JJ cord-022526-j9kg00qf 3284 3 signs sign NNS cord-022526-j9kg00qf 3284 4 include include VBP cord-022526-j9kg00qf 3284 5 alimentary alimentary JJ cord-022526-j9kg00qf 3284 6 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 3284 7 , , , cord-022526-j9kg00qf 3284 8 granulomatous granulomatous JJ cord-022526-j9kg00qf 3284 9 enteritis enteritis NN cord-022526-j9kg00qf 3284 10 , , , cord-022526-j9kg00qf 3284 11 multisystemic multisystemic NNP cord-022526-j9kg00qf 3284 12 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3284 13 epitheliotropic epitheliotropic NNP cord-022526-j9kg00qf 3284 14 disease disease NN cord-022526-j9kg00qf 3284 15 ( ( -LRB- cord-022526-j9kg00qf 3284 16 MEED MEED NNP cord-022526-j9kg00qf 3284 17 ) ) -RRB- cord-022526-j9kg00qf 3284 18 , , , cord-022526-j9kg00qf 3284 19 and and CC cord-022526-j9kg00qf 3284 20 lymphocyticplasmacytic lymphocyticplasmacytic JJ cord-022526-j9kg00qf 3284 21 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3284 22 - - HYPH cord-022526-j9kg00qf 3284 23 conditions condition NNS cord-022526-j9kg00qf 3284 24 affecting affect VBG cord-022526-j9kg00qf 3284 25 young young JJ cord-022526-j9kg00qf 3284 26 and and CC cord-022526-j9kg00qf 3284 27 adult adult NN cord-022526-j9kg00qf 3284 28 horses horse NNS cord-022526-j9kg00qf 3284 29 . . . cord-022526-j9kg00qf 3285 1 Proliferative proliferative JJ cord-022526-j9kg00qf 3285 2 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3285 3 , , , cord-022526-j9kg00qf 3285 4 2 2 CD cord-022526-j9kg00qf 3285 5 a a DT cord-022526-j9kg00qf 3285 6 transmissible transmissible JJ cord-022526-j9kg00qf 3285 7 disease disease NN cord-022526-j9kg00qf 3285 8 of of IN cord-022526-j9kg00qf 3285 9 foals foal NNS cord-022526-j9kg00qf 3285 10 3 3 CD cord-022526-j9kg00qf 3285 11 to to TO cord-022526-j9kg00qf 3285 12 7 7 CD cord-022526-j9kg00qf 3285 13 months month NNS cord-022526-j9kg00qf 3285 14 of of IN cord-022526-j9kg00qf 3285 15 age age NN cord-022526-j9kg00qf 3285 16 characterized characterize VBN cord-022526-j9kg00qf 3285 17 by by IN cord-022526-j9kg00qf 3285 18 significant significant JJ cord-022526-j9kg00qf 3285 19 small small JJ cord-022526-j9kg00qf 3285 20 intestinal intestinal JJ cord-022526-j9kg00qf 3285 21 pathologic pathologic JJ cord-022526-j9kg00qf 3285 22 changes change NNS cord-022526-j9kg00qf 3285 23 , , , cord-022526-j9kg00qf 3285 24 will will MD cord-022526-j9kg00qf 3285 25 be be VB cord-022526-j9kg00qf 3285 26 included include VBN cord-022526-j9kg00qf 3285 27 in in IN cord-022526-j9kg00qf 3285 28 this this DT cord-022526-j9kg00qf 3285 29 group group NN cord-022526-j9kg00qf 3285 30 . . . cord-022526-j9kg00qf 3286 1 However however RB cord-022526-j9kg00qf 3286 2 , , , cord-022526-j9kg00qf 3286 3 several several JJ cord-022526-j9kg00qf 3286 4 other other JJ cord-022526-j9kg00qf 3286 5 primarily primarily RB cord-022526-j9kg00qf 3286 6 small small JJ cord-022526-j9kg00qf 3286 7 intestinal intestinal JJ cord-022526-j9kg00qf 3286 8 conditions condition NNS cord-022526-j9kg00qf 3286 9 described describe VBN cord-022526-j9kg00qf 3286 10 from from IN cord-022526-j9kg00qf 3286 11 a a DT cord-022526-j9kg00qf 3286 12 morphologic morphologic JJ cord-022526-j9kg00qf 3286 13 perspective perspective NN cord-022526-j9kg00qf 3286 14 , , , cord-022526-j9kg00qf 3286 15 such such JJ cord-022526-j9kg00qf 3286 16 as as IN cord-022526-j9kg00qf 3286 17 chronic chronic JJ cord-022526-j9kg00qf 3286 18 postinfarctive postinfarctive JJ cord-022526-j9kg00qf 3286 19 inflammation inflammation NN cord-022526-j9kg00qf 3286 20 and and CC cord-022526-j9kg00qf 3286 21 mycobacterial mycobacterial JJ cord-022526-j9kg00qf 3286 22 infections infection NNS cord-022526-j9kg00qf 3286 23 , , , cord-022526-j9kg00qf 3286 24 3 3 CD cord-022526-j9kg00qf 3286 25 will will MD cord-022526-j9kg00qf 3286 26 not not RB cord-022526-j9kg00qf 3286 27 be be VB cord-022526-j9kg00qf 3286 28 discussed discuss VBN cord-022526-j9kg00qf 3286 29 . . . cord-022526-j9kg00qf 3287 1 In in IN cord-022526-j9kg00qf 3287 2 addition addition NN cord-022526-j9kg00qf 3287 3 , , , cord-022526-j9kg00qf 3287 4 a a DT cord-022526-j9kg00qf 3287 5 single single JJ cord-022526-j9kg00qf 3287 6 case case NN cord-022526-j9kg00qf 3287 7 of of IN cord-022526-j9kg00qf 3287 8 AA AA NNP cord-022526-j9kg00qf 3287 9 amyloid amyloid NN cord-022526-j9kg00qf 3287 10 - - HYPH cord-022526-j9kg00qf 3287 11 associated associate VBN cord-022526-j9kg00qf 3287 12 gastroenteropathy gastroenteropathy NNP cord-022526-j9kg00qf 3287 13 in in IN cord-022526-j9kg00qf 3287 14 an an DT cord-022526-j9kg00qf 3287 15 18-year 18-year JJ cord-022526-j9kg00qf 3287 16 - - HYPH cord-022526-j9kg00qf 3287 17 old old JJ cord-022526-j9kg00qf 3287 18 Morgan Morgan NNP cord-022526-j9kg00qf 3287 19 stallion stallion NN cord-022526-j9kg00qf 3287 20 that that WDT cord-022526-j9kg00qf 3287 21 had have VBD cord-022526-j9kg00qf 3287 22 evidence evidence NN cord-022526-j9kg00qf 3287 23 of of IN cord-022526-j9kg00qf 3287 24 severe severe JJ cord-022526-j9kg00qf 3287 25 malabsorption malabsorption NN cord-022526-j9kg00qf 3287 26 based base VBN cord-022526-j9kg00qf 3287 27 on on IN cord-022526-j9kg00qf 3287 28 poor poor JJ cord-022526-j9kg00qf 3287 29 D d NN cord-022526-j9kg00qf 3287 30 - - HYPH cord-022526-j9kg00qf 3287 31 xylose xylose NN cord-022526-j9kg00qf 3287 32 absorption absorption NN cord-022526-j9kg00qf 3287 33 is be VBZ cord-022526-j9kg00qf 3287 34 included include VBN cord-022526-j9kg00qf 3287 35 . . . cord-022526-j9kg00qf 3288 1 4 4 LS cord-022526-j9kg00qf 3289 1 For for IN cord-022526-j9kg00qf 3289 2 comparative comparative JJ cord-022526-j9kg00qf 3289 3 purposes purpose NNS cord-022526-j9kg00qf 3289 4 , , , cord-022526-j9kg00qf 3289 5 Table table NN cord-022526-j9kg00qf 3289 6 13 13 CD cord-022526-j9kg00qf 3289 7 .12 .12 CD cord-022526-j9kg00qf 3289 8 - - SYM cord-022526-j9kg00qf 3289 9 1 1 CD cord-022526-j9kg00qf 3289 10 lists list VBZ cord-022526-j9kg00qf 3289 11 the the DT cord-022526-j9kg00qf 3289 12 clinical clinical JJ cord-022526-j9kg00qf 3289 13 and and CC cord-022526-j9kg00qf 3289 14 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 3289 15 features feature NNS cord-022526-j9kg00qf 3289 16 of of IN cord-022526-j9kg00qf 3289 17 the the DT cord-022526-j9kg00qf 3289 18 diseases disease NNS cord-022526-j9kg00qf 3289 19 , , , cord-022526-j9kg00qf 3289 20 and and CC cord-022526-j9kg00qf 3289 21 Tables Tables NNPS cord-022526-j9kg00qf 3289 22 13.12 13.12 CD cord-022526-j9kg00qf 3289 23 - - SYM cord-022526-j9kg00qf 3289 24 2 2 CD cord-022526-j9kg00qf 3289 25 and and CC cord-022526-j9kg00qf 3289 26 13.12 13.12 CD cord-022526-j9kg00qf 3289 27 - - SYM cord-022526-j9kg00qf 3289 28 3 3 CD cord-022526-j9kg00qf 3290 1 present present VB cord-022526-j9kg00qf 3290 2 the the DT cord-022526-j9kg00qf 3290 3 gross gross JJ cord-022526-j9kg00qf 3290 4 morphologic morphologic JJ cord-022526-j9kg00qf 3290 5 and and CC cord-022526-j9kg00qf 3290 6 histopathologic histopathologic JJ cord-022526-j9kg00qf 3290 7 findings finding NNS cord-022526-j9kg00qf 3290 8 , , , cord-022526-j9kg00qf 3290 9 respectively respectively RB cord-022526-j9kg00qf 3290 10 . . . cord-022526-j9kg00qf 3291 1 The the DT cord-022526-j9kg00qf 3291 2 extent extent NN cord-022526-j9kg00qf 3291 3 of of IN cord-022526-j9kg00qf 3291 4 small small JJ cord-022526-j9kg00qf 3291 5 intestinal intestinal JJ cord-022526-j9kg00qf 3291 6 disease disease NN cord-022526-j9kg00qf 3291 7 is be VBZ cord-022526-j9kg00qf 3291 8 the the DT cord-022526-j9kg00qf 3291 9 key key NN cord-022526-j9kg00qf 3291 10 to to TO cord-022526-j9kg00qf 3291 11 determine determine VB cord-022526-j9kg00qf 3291 12 whether whether IN cord-022526-j9kg00qf 3291 13 one one PRP cord-022526-j9kg00qf 3291 14 can can MD cord-022526-j9kg00qf 3291 15 demonstrate demonstrate VB cord-022526-j9kg00qf 3291 16 malabsorption malabsorption NN cord-022526-j9kg00qf 3291 17 based base VBN cord-022526-j9kg00qf 3291 18 on on IN cord-022526-j9kg00qf 3291 19 abnormal abnormal JJ cord-022526-j9kg00qf 3291 20 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3291 21 absorption absorption NN cord-022526-j9kg00qf 3291 22 . . . cord-022526-j9kg00qf 3292 1 As as IN cord-022526-j9kg00qf 3292 2 described describe VBN cord-022526-j9kg00qf 3292 3 in in IN cord-022526-j9kg00qf 3292 4 Chapter chapter NN cord-022526-j9kg00qf 3292 5 13.4 13.4 CD cord-022526-j9kg00qf 3292 6 , , , cord-022526-j9kg00qf 3292 7 this this DT cord-022526-j9kg00qf 3292 8 is be VBZ cord-022526-j9kg00qf 3292 9 not not RB cord-022526-j9kg00qf 3292 10 an an DT cord-022526-j9kg00qf 3292 11 all all RB cord-022526-j9kg00qf 3292 12 - - HYPH cord-022526-j9kg00qf 3292 13 or or CC cord-022526-j9kg00qf 3292 14 - - HYPH cord-022526-j9kg00qf 3292 15 nothing nothing NN cord-022526-j9kg00qf 3292 16 situation situation NN cord-022526-j9kg00qf 3292 17 . . . cord-022526-j9kg00qf 3293 1 In in IN cord-022526-j9kg00qf 3293 2 the the DT cord-022526-j9kg00qf 3293 3 same same JJ cord-022526-j9kg00qf 3293 4 animal animal NN cord-022526-j9kg00qf 3293 5 the the DT cord-022526-j9kg00qf 3293 6 staging staging NN cord-022526-j9kg00qf 3293 7 of of IN cord-022526-j9kg00qf 3293 8 the the DT cord-022526-j9kg00qf 3293 9 pathologic pathologic JJ cord-022526-j9kg00qf 3293 10 changes change NNS cord-022526-j9kg00qf 3293 11 differs differ VBZ cord-022526-j9kg00qf 3293 12 in in IN cord-022526-j9kg00qf 3293 13 different different JJ cord-022526-j9kg00qf 3293 14 regions region NNS cord-022526-j9kg00qf 3293 15 of of IN cord-022526-j9kg00qf 3293 16 the the DT cord-022526-j9kg00qf 3293 17 small small JJ cord-022526-j9kg00qf 3293 18 and and CC cord-022526-j9kg00qf 3293 19 large large JJ cord-022526-j9kg00qf 3293 20 intestines intestine NNS cord-022526-j9kg00qf 3293 21 , , , cord-022526-j9kg00qf 3293 22 thus thus RB cord-022526-j9kg00qf 3293 23 influencing influence VBG cord-022526-j9kg00qf 3293 24 severity severity NN cord-022526-j9kg00qf 3293 25 of of IN cord-022526-j9kg00qf 3293 26 clinical clinical JJ cord-022526-j9kg00qf 3293 27 signs sign NNS cord-022526-j9kg00qf 3293 28 and and CC cord-022526-j9kg00qf 3293 29 absorption absorption NN cord-022526-j9kg00qf 3293 30 findings finding NNS cord-022526-j9kg00qf 3293 31 . . . cord-022526-j9kg00qf 3294 1 Furthermore furthermore RB cord-022526-j9kg00qf 3294 2 , , , cord-022526-j9kg00qf 3294 3 the the DT cord-022526-j9kg00qf 3294 4 extent extent NN cord-022526-j9kg00qf 3294 5 of of IN cord-022526-j9kg00qf 3294 6 pathologic pathologic JJ cord-022526-j9kg00qf 3294 7 changes change NNS cord-022526-j9kg00qf 3294 8 in in IN cord-022526-j9kg00qf 3294 9 different different JJ cord-022526-j9kg00qf 3294 10 animals animal NNS cord-022526-j9kg00qf 3294 11 with with IN cord-022526-j9kg00qf 3294 12 ultimately ultimately RB cord-022526-j9kg00qf 3294 13 the the DT cord-022526-j9kg00qf 3294 14 same same JJ cord-022526-j9kg00qf 3294 15 morphologic morphologic JJ cord-022526-j9kg00qf 3294 16 diagnosis diagnosis NN cord-022526-j9kg00qf 3294 17 affects affect VBZ cord-022526-j9kg00qf 3294 18 absorption absorption NN cord-022526-j9kg00qf 3294 19 studies study NNS cord-022526-j9kg00qf 3294 20 and and CC cord-022526-j9kg00qf 3294 21 progress progress NN cord-022526-j9kg00qf 3294 22 of of IN cord-022526-j9kg00qf 3294 23 the the DT cord-022526-j9kg00qf 3294 24 disease disease NN cord-022526-j9kg00qf 3294 25 . . . cord-022526-j9kg00qf 3295 1 Early early JJ cord-022526-j9kg00qf 3295 2 diagnosis diagnosis NN cord-022526-j9kg00qf 3295 3 remains remain VBZ cord-022526-j9kg00qf 3295 4 a a DT cord-022526-j9kg00qf 3295 5 challenge challenge NN cord-022526-j9kg00qf 3295 6 , , , cord-022526-j9kg00qf 3295 7 and and CC cord-022526-j9kg00qf 3295 8 even even RB cord-022526-j9kg00qf 3295 9 multiple multiple JJ cord-022526-j9kg00qf 3295 10 intestinal intestinal JJ cord-022526-j9kg00qf 3295 11 biopsies biopsy NNS cord-022526-j9kg00qf 3295 12 taken take VBN cord-022526-j9kg00qf 3295 13 at at IN cord-022526-j9kg00qf 3295 14 exploratory exploratory JJ cord-022526-j9kg00qf 3295 15 laparotomy laparotomy NN cord-022526-j9kg00qf 3295 16 may may MD cord-022526-j9kg00qf 3295 17 prove prove VB cord-022526-j9kg00qf 3295 18 unhelpful unhelpful JJ cord-022526-j9kg00qf 3295 19 . . . cord-022526-j9kg00qf 3296 1 By by IN cord-022526-j9kg00qf 3296 2 contrast contrast NN cord-022526-j9kg00qf 3296 3 , , , cord-022526-j9kg00qf 3296 4 intestinal intestinal JJ cord-022526-j9kg00qf 3296 5 infiltration infiltration NN cord-022526-j9kg00qf 3296 6 with with IN cord-022526-j9kg00qf 3296 7 the the DT cord-022526-j9kg00qf 3296 8 predominant predominant JJ cord-022526-j9kg00qf 3296 9 cell cell NN cord-022526-j9kg00qf 3296 10 types type NNS cord-022526-j9kg00qf 3296 11 can can MD cord-022526-j9kg00qf 3296 12 be be VB cord-022526-j9kg00qf 3296 13 found find VBN cord-022526-j9kg00qf 3296 14 in in IN cord-022526-j9kg00qf 3296 15 grossly grossly RB cord-022526-j9kg00qf 3296 16 normal normal JJ cord-022526-j9kg00qf 3296 17 appearing appear VBG cord-022526-j9kg00qf 3296 18 intestinal intestinal JJ cord-022526-j9kg00qf 3296 19 tissue tissue NN cord-022526-j9kg00qf 3296 20 . . . cord-022526-j9kg00qf 3297 1 Alimentary alimentary JJ cord-022526-j9kg00qf 3297 2 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 3297 3 of of IN cord-022526-j9kg00qf 3297 4 the the DT cord-022526-j9kg00qf 3297 5 horse horse NN cord-022526-j9kg00qf 3297 6 may may MD cord-022526-j9kg00qf 3297 7 represent represent VB cord-022526-j9kg00qf 3297 8 a a DT cord-022526-j9kg00qf 3297 9 primary primary JJ cord-022526-j9kg00qf 3297 10 neoplasia neoplasia NN cord-022526-j9kg00qf 3297 11 of of IN cord-022526-j9kg00qf 3297 12 the the DT cord-022526-j9kg00qf 3297 13 gut gut NN cord-022526-j9kg00qf 3297 14 associated associate VBN cord-022526-j9kg00qf 3297 15 lymphoid lymphoid JJ cord-022526-j9kg00qf 3297 16 tissue tissue NN cord-022526-j9kg00qf 3297 17 with with IN cord-022526-j9kg00qf 3297 18 significant significant JJ cord-022526-j9kg00qf 3297 19 cellular cellular JJ cord-022526-j9kg00qf 3297 20 infiltration infiltration NN cord-022526-j9kg00qf 3297 21 of of IN cord-022526-j9kg00qf 3297 22 the the DT cord-022526-j9kg00qf 3297 23 small small JJ cord-022526-j9kg00qf 3297 24 intestine intestine NN cord-022526-j9kg00qf 3297 25 and and CC cord-022526-j9kg00qf 3297 26 associated associate VBD cord-022526-j9kg00qf 3297 27 lymph lymph NN cord-022526-j9kg00qf 3297 28 nodes node NNS cord-022526-j9kg00qf 3297 29 with with IN cord-022526-j9kg00qf 3297 30 minimal minimal JJ cord-022526-j9kg00qf 3297 31 large large JJ cord-022526-j9kg00qf 3297 32 intestinal intestinal JJ cord-022526-j9kg00qf 3297 33 or or CC cord-022526-j9kg00qf 3297 34 systemic systemic JJ cord-022526-j9kg00qf 3297 35 involvement involvement NN cord-022526-j9kg00qf 3297 36 . . . cord-022526-j9kg00qf 3298 1 Case case NN cord-022526-j9kg00qf 3298 2 series series NN cord-022526-j9kg00qf 3298 3 and and CC cord-022526-j9kg00qf 3298 4 pathology pathology NN cord-022526-j9kg00qf 3298 5 reports report NNS cord-022526-j9kg00qf 3298 6 indicate indicate VBP cord-022526-j9kg00qf 3298 7 that that IN cord-022526-j9kg00qf 3298 8 young young JJ cord-022526-j9kg00qf 3298 9 horses horse NNS cord-022526-j9kg00qf 3298 10 2 2 CD cord-022526-j9kg00qf 3298 11 to to IN cord-022526-j9kg00qf 3298 12 4 4 CD cord-022526-j9kg00qf 3298 13 years year NNS cord-022526-j9kg00qf 3298 14 of of IN cord-022526-j9kg00qf 3298 15 age age NN cord-022526-j9kg00qf 3298 16 primarily primarily RB cord-022526-j9kg00qf 3298 17 are be VBP cord-022526-j9kg00qf 3298 18 affected affect VBN cord-022526-j9kg00qf 3298 19 , , , cord-022526-j9kg00qf 3298 20 although although IN cord-022526-j9kg00qf 3298 21 the the DT cord-022526-j9kg00qf 3298 22 age age NN cord-022526-j9kg00qf 3298 23 range range NN cord-022526-j9kg00qf 3298 24 can can MD cord-022526-j9kg00qf 3298 25 be be VB cord-022526-j9kg00qf 3298 26 broad broad JJ cord-022526-j9kg00qf 3298 27 . . . cord-022526-j9kg00qf 3299 1 [ [ -LRB- cord-022526-j9kg00qf 3299 2 5 5 CD cord-022526-j9kg00qf 3299 3 ] ] -RRB- cord-022526-j9kg00qf 3299 4 [ [ -LRB- cord-022526-j9kg00qf 3299 5 6 6 CD cord-022526-j9kg00qf 3299 6 ] ] -RRB- cord-022526-j9kg00qf 3299 7 [ [ -LRB- cord-022526-j9kg00qf 3299 8 7 7 CD cord-022526-j9kg00qf 3299 9 ] ] -RRB- cord-022526-j9kg00qf 3300 1 No no DT cord-022526-j9kg00qf 3300 2 breed breed NN cord-022526-j9kg00qf 3300 3 or or CC cord-022526-j9kg00qf 3300 4 sex sex NN cord-022526-j9kg00qf 3300 5 predilection predilection NN cord-022526-j9kg00qf 3300 6 exists exist VBZ cord-022526-j9kg00qf 3300 7 . . . cord-022526-j9kg00qf 3301 1 Prevalence prevalence NN cord-022526-j9kg00qf 3301 2 is be VBZ cord-022526-j9kg00qf 3301 3 unknown unknown JJ cord-022526-j9kg00qf 3301 4 . . . cord-022526-j9kg00qf 3302 1 Despite despite IN cord-022526-j9kg00qf 3302 2 the the DT cord-022526-j9kg00qf 3302 3 progressive progressive JJ cord-022526-j9kg00qf 3302 4 nature nature NN cord-022526-j9kg00qf 3302 5 of of IN cord-022526-j9kg00qf 3302 6 lymphomata lymphomata NNP cord-022526-j9kg00qf 3302 7 , , , cord-022526-j9kg00qf 3302 8 onset onset NN cord-022526-j9kg00qf 3302 9 of of IN cord-022526-j9kg00qf 3302 10 clinical clinical JJ cord-022526-j9kg00qf 3302 11 signs sign NNS cord-022526-j9kg00qf 3302 12 can can MD cord-022526-j9kg00qf 3302 13 be be VB cord-022526-j9kg00qf 3302 14 rapid rapid JJ cord-022526-j9kg00qf 3302 15 and and CC cord-022526-j9kg00qf 3302 16 the the DT cord-022526-j9kg00qf 3302 17 animal animal NN cord-022526-j9kg00qf 3302 18 may may MD cord-022526-j9kg00qf 3302 19 become become VB cord-022526-j9kg00qf 3302 20 acutely acutely RB cord-022526-j9kg00qf 3302 21 ill ill JJ cord-022526-j9kg00qf 3302 22 . . . cord-022526-j9kg00qf 3303 1 As as IN cord-022526-j9kg00qf 3303 2 with with IN cord-022526-j9kg00qf 3303 3 all all DT cord-022526-j9kg00qf 3303 4 adult adult NN cord-022526-j9kg00qf 3303 5 cases case NNS cord-022526-j9kg00qf 3303 6 of of IN cord-022526-j9kg00qf 3303 7 chronic chronic JJ cord-022526-j9kg00qf 3303 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 3303 9 bowel bowel NN cord-022526-j9kg00qf 3303 10 disease disease NN cord-022526-j9kg00qf 3303 11 , , , cord-022526-j9kg00qf 3303 12 antemortem antemortem NNP cord-022526-j9kg00qf 3303 13 diagnosis diagnosis NN cord-022526-j9kg00qf 3303 14 is be VBZ cord-022526-j9kg00qf 3303 15 by by IN cord-022526-j9kg00qf 3303 16 a a DT cord-022526-j9kg00qf 3303 17 process process NN cord-022526-j9kg00qf 3303 18 of of IN cord-022526-j9kg00qf 3303 19 exclusion exclusion NN cord-022526-j9kg00qf 3303 20 and and CC cord-022526-j9kg00qf 3303 21 usually usually RB cord-022526-j9kg00qf 3303 22 is be VBZ cord-022526-j9kg00qf 3303 23 confirmed confirm VBN cord-022526-j9kg00qf 3303 24 post post AFX cord-022526-j9kg00qf 3303 25 mortem mortem NN cord-022526-j9kg00qf 3303 26 . . . cord-022526-j9kg00qf 3304 1 Frequently frequently RB cord-022526-j9kg00qf 3304 2 , , , cord-022526-j9kg00qf 3304 3 the the DT cord-022526-j9kg00qf 3304 4 horse horse NN cord-022526-j9kg00qf 3304 5 has have VBZ cord-022526-j9kg00qf 3304 6 anemia anemia NN cord-022526-j9kg00qf 3304 7 , , , cord-022526-j9kg00qf 3304 8 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 3304 9 , , , cord-022526-j9kg00qf 3304 10 neutrophilia neutrophilia NNP cord-022526-j9kg00qf 3304 11 or or CC cord-022526-j9kg00qf 3304 12 neutropenia neutropenia NN cord-022526-j9kg00qf 3304 13 , , , cord-022526-j9kg00qf 3304 14 hypoalbuminemia hypoalbuminemia NNP cord-022526-j9kg00qf 3304 15 , , , cord-022526-j9kg00qf 3304 16 normal normal JJ cord-022526-j9kg00qf 3304 17 serum serum NN cord-022526-j9kg00qf 3304 18 protein protein NN cord-022526-j9kg00qf 3304 19 or or CC cord-022526-j9kg00qf 3304 20 hyperproteinemia hyperproteinemia NN cord-022526-j9kg00qf 3304 21 , , , cord-022526-j9kg00qf 3304 22 and and CC cord-022526-j9kg00qf 3304 23 hypergammaglobulinemia hypergammaglobulinemia NNP cord-022526-j9kg00qf 3304 24 . . . cord-022526-j9kg00qf 3305 1 Lymphocytosis Lymphocytosis NNP cord-022526-j9kg00qf 3305 2 is be VBZ cord-022526-j9kg00qf 3305 3 rare rare JJ cord-022526-j9kg00qf 3305 4 . . . cord-022526-j9kg00qf 3306 1 One one CD cord-022526-j9kg00qf 3306 2 may may MD cord-022526-j9kg00qf 3306 3 palpate palpate VB cord-022526-j9kg00qf 3306 4 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 3306 5 masses masse NNS cord-022526-j9kg00qf 3306 6 , , , cord-022526-j9kg00qf 3306 7 mainly mainly RB cord-022526-j9kg00qf 3306 8 enlarged enlarge VBN cord-022526-j9kg00qf 3306 9 mesenteric mesenteric JJ cord-022526-j9kg00qf 3306 10 lymph lymph NN cord-022526-j9kg00qf 3306 11 nodes node NNS cord-022526-j9kg00qf 3306 12 , , , cord-022526-j9kg00qf 3306 13 rectally rectally RB cord-022526-j9kg00qf 3306 14 . . . cord-022526-j9kg00qf 3307 1 Abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 3307 2 has have VBZ cord-022526-j9kg00qf 3307 3 been be VBN cord-022526-j9kg00qf 3307 4 of of IN cord-022526-j9kg00qf 3307 5 diagnostic diagnostic JJ cord-022526-j9kg00qf 3307 6 value value NN cord-022526-j9kg00qf 3307 7 . . . cord-022526-j9kg00qf 3308 1 Carbohydrate carbohydrate NN cord-022526-j9kg00qf 3308 2 absorption absorption NN cord-022526-j9kg00qf 3308 3 tests test NNS cord-022526-j9kg00qf 3308 4 usually usually RB cord-022526-j9kg00qf 3308 5 reveal reveal VBP cord-022526-j9kg00qf 3308 6 partial partial JJ cord-022526-j9kg00qf 3308 7 to to IN cord-022526-j9kg00qf 3308 8 total total JJ cord-022526-j9kg00qf 3308 9 malabsorption malabsorption NN cord-022526-j9kg00qf 3308 10 indicative indicative JJ cord-022526-j9kg00qf 3308 11 of of IN cord-022526-j9kg00qf 3308 12 the the DT cord-022526-j9kg00qf 3308 13 severely severely RB cord-022526-j9kg00qf 3308 14 reduced reduce VBN cord-022526-j9kg00qf 3308 15 surface surface NN cord-022526-j9kg00qf 3308 16 area area NN cord-022526-j9kg00qf 3308 17 resulting result VBG cord-022526-j9kg00qf 3308 18 from from IN cord-022526-j9kg00qf 3308 19 significant significant JJ cord-022526-j9kg00qf 3308 20 villous villous JJ cord-022526-j9kg00qf 3308 21 atrophy atrophy NN cord-022526-j9kg00qf 3308 22 and and CC cord-022526-j9kg00qf 3308 23 the the DT cord-022526-j9kg00qf 3308 24 extensive extensive JJ cord-022526-j9kg00qf 3308 25 mucosal mucosal NN cord-022526-j9kg00qf 3308 26 or or CC cord-022526-j9kg00qf 3308 27 transmural transmural JJ cord-022526-j9kg00qf 3308 28 infiltration infiltration NN cord-022526-j9kg00qf 3308 29 . . . cord-022526-j9kg00qf 3309 1 Rectal rectal JJ cord-022526-j9kg00qf 3309 2 biopsy biopsy NN cord-022526-j9kg00qf 3309 3 has have VBZ cord-022526-j9kg00qf 3309 4 aided aid VBN cord-022526-j9kg00qf 3309 5 diagnosis diagnosis NN cord-022526-j9kg00qf 3309 6 . . . cord-022526-j9kg00qf 3310 1 Early early JJ cord-022526-j9kg00qf 3310 2 confirmation confirmation NN cord-022526-j9kg00qf 3310 3 of of IN cord-022526-j9kg00qf 3310 4 a a DT cord-022526-j9kg00qf 3310 5 suspected suspect VBN cord-022526-j9kg00qf 3310 6 diagnosis diagnosis NN cord-022526-j9kg00qf 3310 7 necessitates necessitate VBZ cord-022526-j9kg00qf 3310 8 exploratory exploratory JJ cord-022526-j9kg00qf 3310 9 laparotomy laparotomy NN cord-022526-j9kg00qf 3310 10 to to TO cord-022526-j9kg00qf 3310 11 obtain obtain VB cord-022526-j9kg00qf 3310 12 multiple multiple JJ cord-022526-j9kg00qf 3310 13 intestinal intestinal JJ cord-022526-j9kg00qf 3310 14 and and CC cord-022526-j9kg00qf 3310 15 lymph lymph NN cord-022526-j9kg00qf 3310 16 node node NN cord-022526-j9kg00qf 3310 17 biopsies biopsy NNS cord-022526-j9kg00qf 3310 18 . . . cord-022526-j9kg00qf 3311 1 In in IN cord-022526-j9kg00qf 3311 2 the the DT cord-022526-j9kg00qf 3311 3 future future NN cord-022526-j9kg00qf 3311 4 , , , cord-022526-j9kg00qf 3311 5 markers marker NNS cord-022526-j9kg00qf 3311 6 of of IN cord-022526-j9kg00qf 3311 7 cancer cancer NN cord-022526-j9kg00qf 3311 8 cells cell NNS cord-022526-j9kg00qf 3311 9 may may MD cord-022526-j9kg00qf 3311 10 become become VB cord-022526-j9kg00qf 3311 11 available available JJ cord-022526-j9kg00qf 3311 12 and and CC cord-022526-j9kg00qf 3311 13 may may MD cord-022526-j9kg00qf 3311 14 be be VB cord-022526-j9kg00qf 3311 15 cost cost NN cord-022526-j9kg00qf 3311 16 - - HYPH cord-022526-j9kg00qf 3311 17 effective effective JJ cord-022526-j9kg00qf 3311 18 to to TO cord-022526-j9kg00qf 3311 19 aid aid VB cord-022526-j9kg00qf 3311 20 diagnosis diagnosis NN cord-022526-j9kg00qf 3311 21 . . . cord-022526-j9kg00qf 3312 1 Prognosis prognosis NN cord-022526-j9kg00qf 3312 2 is be VBZ cord-022526-j9kg00qf 3312 3 poor poor JJ cord-022526-j9kg00qf 3312 4 . . . cord-022526-j9kg00qf 3313 1 Natural natural JJ cord-022526-j9kg00qf 3313 2 progress progress NN cord-022526-j9kg00qf 3313 3 of of IN cord-022526-j9kg00qf 3313 4 the the DT cord-022526-j9kg00qf 3313 5 disease disease NN cord-022526-j9kg00qf 3313 6 is be VBZ cord-022526-j9kg00qf 3313 7 unknown unknown JJ cord-022526-j9kg00qf 3313 8 . . . cord-022526-j9kg00qf 3314 1 Most Most JJS cord-022526-j9kg00qf 3314 2 horses horse NNS cord-022526-j9kg00qf 3314 3 are be VBP cord-022526-j9kg00qf 3314 4 presented present VBN cord-022526-j9kg00qf 3314 5 in in IN cord-022526-j9kg00qf 3314 6 an an DT cord-022526-j9kg00qf 3314 7 advanced advanced JJ cord-022526-j9kg00qf 3314 8 state state NN cord-022526-j9kg00qf 3314 9 of of IN cord-022526-j9kg00qf 3314 10 disease disease NN cord-022526-j9kg00qf 3314 11 . . . cord-022526-j9kg00qf 3315 1 Immunosuppressive immunosuppressive JJ cord-022526-j9kg00qf 3315 2 drugs drug NNS cord-022526-j9kg00qf 3315 3 or or CC cord-022526-j9kg00qf 3315 4 chemotherapy chemotherapy NN cord-022526-j9kg00qf 3315 5 may may MD cord-022526-j9kg00qf 3315 6 afford afford VB cord-022526-j9kg00qf 3315 7 temporary temporary JJ cord-022526-j9kg00qf 3315 8 improvement improvement NN cord-022526-j9kg00qf 3315 9 . . . cord-022526-j9kg00qf 3316 1 However however RB cord-022526-j9kg00qf 3316 2 , , , cord-022526-j9kg00qf 3316 3 outcome outcome NN cord-022526-j9kg00qf 3316 4 is be VBZ cord-022526-j9kg00qf 3316 5 unaffected unaffected JJ cord-022526-j9kg00qf 3316 6 . . . cord-022526-j9kg00qf 3317 1 The the DT cord-022526-j9kg00qf 3317 2 chronic chronic JJ cord-022526-j9kg00qf 3317 3 wasting waste VBG cord-022526-j9kg00qf 3317 4 condition condition NN cord-022526-j9kg00qf 3317 5 granulomatous granulomatous JJ cord-022526-j9kg00qf 3317 6 enteritis enteritis NN cord-022526-j9kg00qf 3317 7 was be VBD cord-022526-j9kg00qf 3317 8 first first RB cord-022526-j9kg00qf 3317 9 described describe VBN cord-022526-j9kg00qf 3317 10 in in IN cord-022526-j9kg00qf 3317 11 1974 1974 CD cord-022526-j9kg00qf 3317 12 8 8 CD cord-022526-j9kg00qf 3317 13 ; ; : cord-022526-j9kg00qf 3317 14 9 9 CD cord-022526-j9kg00qf 3317 15 of of IN cord-022526-j9kg00qf 3317 16 10 10 CD cord-022526-j9kg00qf 3317 17 horses horse NNS cord-022526-j9kg00qf 3317 18 were be VBD cord-022526-j9kg00qf 3317 19 young young JJ cord-022526-j9kg00qf 3317 20 Standardbreds Standardbreds NNPS cord-022526-j9kg00qf 3317 21 . . . cord-022526-j9kg00qf 3318 1 Most Most JJS cord-022526-j9kg00qf 3318 2 affected affected JJ cord-022526-j9kg00qf 3318 3 horses horse NNS cord-022526-j9kg00qf 3318 4 are be VBP cord-022526-j9kg00qf 3318 5 2 2 CD cord-022526-j9kg00qf 3318 6 to to TO cord-022526-j9kg00qf 3318 7 3 3 CD cord-022526-j9kg00qf 3318 8 years year NNS cord-022526-j9kg00qf 3318 9 of of IN cord-022526-j9kg00qf 3318 10 age age NN cord-022526-j9kg00qf 3318 11 . . . cord-022526-j9kg00qf 3319 1 Case case NN cord-022526-j9kg00qf 3319 2 reports report NNS cord-022526-j9kg00qf 3319 3 from from IN cord-022526-j9kg00qf 3319 4 many many JJ cord-022526-j9kg00qf 3319 5 countries country NNS cord-022526-j9kg00qf 3319 6 revealed reveal VBD cord-022526-j9kg00qf 3319 7 a a DT cord-022526-j9kg00qf 3319 8 predominance predominance NN cord-022526-j9kg00qf 3319 9 of of IN cord-022526-j9kg00qf 3319 10 Standardbred Standardbred NNP cord-022526-j9kg00qf 3319 11 over over IN cord-022526-j9kg00qf 3319 12 Thoroughbred Thoroughbred NNP cord-022526-j9kg00qf 3319 13 horses horse NNS cord-022526-j9kg00qf 3319 14 by by IN cord-022526-j9kg00qf 3319 15 three three CD cord-022526-j9kg00qf 3319 16 to to IN cord-022526-j9kg00qf 3319 17 one one CD cord-022526-j9kg00qf 3319 18 . . . cord-022526-j9kg00qf 3320 1 9,10 9,10 CD cord-022526-j9kg00qf 3321 1 Some some DT cord-022526-j9kg00qf 3321 2 of of IN cord-022526-j9kg00qf 3321 3 the the DT cord-022526-j9kg00qf 3321 4 Standardbreds Standardbreds NNPS cord-022526-j9kg00qf 3321 5 were be VBD cord-022526-j9kg00qf 3321 6 related relate VBN cord-022526-j9kg00qf 3321 7 , , , cord-022526-j9kg00qf 3321 8 implicating implicate VBG cord-022526-j9kg00qf 3321 9 a a DT cord-022526-j9kg00qf 3321 10 genetic genetic JJ cord-022526-j9kg00qf 3321 11 predisposition predisposition NN cord-022526-j9kg00qf 3321 12 . . . cord-022526-j9kg00qf 3322 1 Prevalence prevalence NN cord-022526-j9kg00qf 3322 2 is be VBZ cord-022526-j9kg00qf 3322 3 low low JJ cord-022526-j9kg00qf 3322 4 . . . cord-022526-j9kg00qf 3323 1 The the DT cord-022526-j9kg00qf 3323 2 condition condition NN cord-022526-j9kg00qf 3323 3 is be VBZ cord-022526-j9kg00qf 3323 4 sporadic sporadic JJ cord-022526-j9kg00qf 3323 5 and and CC cord-022526-j9kg00qf 3323 6 has have VBZ cord-022526-j9kg00qf 3323 7 an an DT cord-022526-j9kg00qf 3323 8 insidious insidious JJ cord-022526-j9kg00qf 3323 9 onset onset NN cord-022526-j9kg00qf 3323 10 , , , cord-022526-j9kg00qf 3323 11 and and CC cord-022526-j9kg00qf 3323 12 the the DT cord-022526-j9kg00qf 3323 13 course course NN cord-022526-j9kg00qf 3323 14 can can MD cord-022526-j9kg00qf 3323 15 be be VB cord-022526-j9kg00qf 3323 16 protracted protract VBN cord-022526-j9kg00qf 3323 17 . . . cord-022526-j9kg00qf 3324 1 Significant significant JJ cord-022526-j9kg00qf 3324 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 3324 3 features feature NNS cord-022526-j9kg00qf 3324 4 include include VBP cord-022526-j9kg00qf 3324 5 anemia anemia NN cord-022526-j9kg00qf 3324 6 , , , cord-022526-j9kg00qf 3324 7 slight slight JJ cord-022526-j9kg00qf 3324 8 increases increase NNS cord-022526-j9kg00qf 3324 9 or or CC cord-022526-j9kg00qf 3324 10 decreases decrease NNS cord-022526-j9kg00qf 3324 11 in in IN cord-022526-j9kg00qf 3324 12 white white JJ cord-022526-j9kg00qf 3324 13 blood blood NN cord-022526-j9kg00qf 3324 14 cell cell NN cord-022526-j9kg00qf 3324 15 counts count NNS cord-022526-j9kg00qf 3324 16 , , , cord-022526-j9kg00qf 3324 17 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3324 18 , , , cord-022526-j9kg00qf 3324 19 normal normal JJ cord-022526-j9kg00qf 3324 20 serum serum NN cord-022526-j9kg00qf 3324 21 protein protein NN cord-022526-j9kg00qf 3324 22 or or CC cord-022526-j9kg00qf 3324 23 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 3324 24 , , , cord-022526-j9kg00qf 3324 25 occasional occasional JJ cord-022526-j9kg00qf 3324 26 increases increase NNS cord-022526-j9kg00qf 3324 27 in in IN cord-022526-j9kg00qf 3324 28 serum serum NN cord-022526-j9kg00qf 3324 29 alkaline alkaline JJ cord-022526-j9kg00qf 3324 30 phosphatase phosphatase NN cord-022526-j9kg00qf 3324 31 activity activity NN cord-022526-j9kg00qf 3324 32 , , , cord-022526-j9kg00qf 3324 33 normal normal JJ cord-022526-j9kg00qf 3324 34 serum serum NN cord-022526-j9kg00qf 3324 35 γ γ NN cord-022526-j9kg00qf 3324 36 - - HYPH cord-022526-j9kg00qf 3324 37 glutamyltransferase glutamyltransferase NN cord-022526-j9kg00qf 3324 38 activity activity NN cord-022526-j9kg00qf 3324 39 , , , cord-022526-j9kg00qf 3324 40 and and CC cord-022526-j9kg00qf 3324 41 enlarged enlarge VBN cord-022526-j9kg00qf 3324 42 mesenteric mesenteric JJ cord-022526-j9kg00qf 3324 43 lymph lymph NN cord-022526-j9kg00qf 3324 44 nodes node NNS cord-022526-j9kg00qf 3324 45 on on IN cord-022526-j9kg00qf 3324 46 rectal rectal JJ cord-022526-j9kg00qf 3324 47 palpation palpation NN cord-022526-j9kg00qf 3324 48 . . . cord-022526-j9kg00qf 3325 1 Reduced reduce VBN cord-022526-j9kg00qf 3325 2 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3325 3 absorption absorption NN cord-022526-j9kg00qf 3325 4 to to IN cord-022526-j9kg00qf 3325 5 the the DT cord-022526-j9kg00qf 3325 6 level level NN cord-022526-j9kg00qf 3325 7 of of IN cord-022526-j9kg00qf 3325 8 partial partial JJ cord-022526-j9kg00qf 3325 9 to to IN cord-022526-j9kg00qf 3325 10 total total JJ cord-022526-j9kg00qf 3325 11 malabsorption malabsorption NN cord-022526-j9kg00qf 3325 12 is be VBZ cord-022526-j9kg00qf 3325 13 reported report VBN cord-022526-j9kg00qf 3325 14 frequently frequently RB cord-022526-j9kg00qf 3325 15 , , , cord-022526-j9kg00qf 3325 16 consistent consistent JJ cord-022526-j9kg00qf 3325 17 with with IN cord-022526-j9kg00qf 3325 18 the the DT cord-022526-j9kg00qf 3325 19 severe severe JJ cord-022526-j9kg00qf 3325 20 morphologic morphologic JJ cord-022526-j9kg00qf 3325 21 changes change NNS cord-022526-j9kg00qf 3325 22 throughout throughout IN cord-022526-j9kg00qf 3325 23 the the DT cord-022526-j9kg00qf 3325 24 small small JJ cord-022526-j9kg00qf 3325 25 intestine intestine NN cord-022526-j9kg00qf 3325 26 . . . cord-022526-j9kg00qf 3326 1 One one PRP cord-022526-j9kg00qf 3326 2 can can MD cord-022526-j9kg00qf 3326 3 attribute attribute VB cord-022526-j9kg00qf 3326 4 the the DT cord-022526-j9kg00qf 3326 5 low low JJ cord-022526-j9kg00qf 3326 6 proportion proportion NN cord-022526-j9kg00qf 3326 7 of of IN cord-022526-j9kg00qf 3326 8 horses horse NNS cord-022526-j9kg00qf 3326 9 exhibiting exhibit VBG cord-022526-j9kg00qf 3326 10 diarrhea diarrhea NN cord-022526-j9kg00qf 3326 11 9,10 9,10 CD cord-022526-j9kg00qf 3326 12 to to IN cord-022526-j9kg00qf 3326 13 the the DT cord-022526-j9kg00qf 3326 14 preferential preferential JJ cord-022526-j9kg00qf 3326 15 distribution distribution NN cord-022526-j9kg00qf 3326 16 of of IN cord-022526-j9kg00qf 3326 17 inflammatory inflammatory JJ cord-022526-j9kg00qf 3326 18 infiltration infiltration NN cord-022526-j9kg00qf 3326 19 in in IN cord-022526-j9kg00qf 3326 20 the the DT cord-022526-j9kg00qf 3326 21 small small JJ cord-022526-j9kg00qf 3326 22 intestine intestine NN cord-022526-j9kg00qf 3326 23 , , , cord-022526-j9kg00qf 3326 24 11 11 CD cord-022526-j9kg00qf 3326 25 with with IN cord-022526-j9kg00qf 3326 26 lesser less JJR cord-022526-j9kg00qf 3326 27 involvement involvement NN cord-022526-j9kg00qf 3326 28 of of IN cord-022526-j9kg00qf 3326 29 the the DT cord-022526-j9kg00qf 3326 30 large large JJ cord-022526-j9kg00qf 3326 31 intestine intestine NN cord-022526-j9kg00qf 3326 32 . . . cord-022526-j9kg00qf 3327 1 Rectal rectal JJ cord-022526-j9kg00qf 3327 2 biopsy biopsy NN cord-022526-j9kg00qf 3327 3 can can MD cord-022526-j9kg00qf 3327 4 be be VB cord-022526-j9kg00qf 3327 5 a a DT cord-022526-j9kg00qf 3327 6 useful useful JJ cord-022526-j9kg00qf 3327 7 aid aid NN cord-022526-j9kg00qf 3327 8 to to IN cord-022526-j9kg00qf 3327 9 diagnosis diagnosis NN cord-022526-j9kg00qf 3327 10 . . . cord-022526-j9kg00qf 3328 1 12 12 CD cord-022526-j9kg00qf 3328 2 Treatment treatment NN cord-022526-j9kg00qf 3328 3 of of IN cord-022526-j9kg00qf 3328 4 horses horse NNS cord-022526-j9kg00qf 3328 5 with with IN cord-022526-j9kg00qf 3328 6 granulomatous granulomatous JJ cord-022526-j9kg00qf 3328 7 enteritis enteritis NN cord-022526-j9kg00qf 3328 8 with with IN cord-022526-j9kg00qf 3328 9 a a DT cord-022526-j9kg00qf 3328 10 variety variety NN cord-022526-j9kg00qf 3328 11 of of IN cord-022526-j9kg00qf 3328 12 drugs drug NNS cord-022526-j9kg00qf 3328 13 , , , cord-022526-j9kg00qf 3328 14 particularly particularly RB cord-022526-j9kg00qf 3328 15 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 3328 16 , , , cord-022526-j9kg00qf 3328 17 has have VBZ cord-022526-j9kg00qf 3328 18 not not RB cord-022526-j9kg00qf 3328 19 affected affect VBN cord-022526-j9kg00qf 3328 20 the the DT cord-022526-j9kg00qf 3328 21 outcome outcome NN cord-022526-j9kg00qf 3328 22 except except IN cord-022526-j9kg00qf 3328 23 in in IN cord-022526-j9kg00qf 3328 24 the the DT cord-022526-j9kg00qf 3328 25 short short JJ cord-022526-j9kg00qf 3328 26 term term NN cord-022526-j9kg00qf 3328 27 . . . cord-022526-j9kg00qf 3329 1 13 13 CD cord-022526-j9kg00qf 3330 1 One one CD cord-022526-j9kg00qf 3330 2 successful successful JJ cord-022526-j9kg00qf 3330 3 response response NN cord-022526-j9kg00qf 3330 4 has have VBZ cord-022526-j9kg00qf 3330 5 been be VBN cord-022526-j9kg00qf 3330 6 reported report VBN cord-022526-j9kg00qf 3330 7 . . . cord-022526-j9kg00qf 3331 1 Prolonged prolonged JJ cord-022526-j9kg00qf 3331 2 corticosteroid corticosteroid NNP cord-022526-j9kg00qf 3331 3 administration administration NN cord-022526-j9kg00qf 3331 4 produced produce VBD cord-022526-j9kg00qf 3331 5 clinical clinical JJ cord-022526-j9kg00qf 3331 6 remission remission NN cord-022526-j9kg00qf 3331 7 in in IN cord-022526-j9kg00qf 3331 8 a a DT cord-022526-j9kg00qf 3331 9 6-year 6-year JJ cord-022526-j9kg00qf 3331 10 - - HYPH cord-022526-j9kg00qf 3331 11 old old JJ cord-022526-j9kg00qf 3331 12 Standardbred Standardbred NNP cord-022526-j9kg00qf 3331 13 gelding gelding NN cord-022526-j9kg00qf 3331 14 based base VBN cord-022526-j9kg00qf 3331 15 on on IN cord-022526-j9kg00qf 3331 16 improvement improvement NN cord-022526-j9kg00qf 3331 17 in in IN cord-022526-j9kg00qf 3331 18 clinical clinical JJ cord-022526-j9kg00qf 3331 19 signs sign NNS cord-022526-j9kg00qf 3331 20 and and CC cord-022526-j9kg00qf 3331 21 in in IN cord-022526-j9kg00qf 3331 22 D d JJ cord-022526-j9kg00qf 3331 23 - - HYPH cord-022526-j9kg00qf 3331 24 xylose xylose NN cord-022526-j9kg00qf 3331 25 absorption absorption NN cord-022526-j9kg00qf 3331 26 . . . cord-022526-j9kg00qf 3332 1 14 14 CD cord-022526-j9kg00qf 3332 2 Five five CD cord-022526-j9kg00qf 3332 3 months month NNS cord-022526-j9kg00qf 3332 4 after after IN cord-022526-j9kg00qf 3332 5 cessation cessation NN cord-022526-j9kg00qf 3332 6 of of IN cord-022526-j9kg00qf 3332 7 approximately approximately RB cord-022526-j9kg00qf 3332 8 5 5 CD cord-022526-j9kg00qf 3332 9 months month NNS cord-022526-j9kg00qf 3332 10 therapy therapy NN cord-022526-j9kg00qf 3332 11 , , , cord-022526-j9kg00qf 3332 12 D d NN cord-022526-j9kg00qf 3332 13 - - HYPH cord-022526-j9kg00qf 3332 14 xylose xylose NN cord-022526-j9kg00qf 3332 15 absorption absorption NN cord-022526-j9kg00qf 3332 16 was be VBD cord-022526-j9kg00qf 3332 17 normal normal JJ cord-022526-j9kg00qf 3332 18 and and CC cord-022526-j9kg00qf 3332 19 the the DT cord-022526-j9kg00qf 3332 20 horse horse NN cord-022526-j9kg00qf 3332 21 was be VBD cord-022526-j9kg00qf 3332 22 bright bright JJ cord-022526-j9kg00qf 3332 23 , , , cord-022526-j9kg00qf 3332 24 alert alert JJ cord-022526-j9kg00qf 3332 25 , , , cord-022526-j9kg00qf 3332 26 and and CC cord-022526-j9kg00qf 3332 27 resumed resume VBD cord-022526-j9kg00qf 3332 28 a a DT cord-022526-j9kg00qf 3332 29 level level NN cord-022526-j9kg00qf 3332 30 of of IN cord-022526-j9kg00qf 3332 31 athletic athletic JJ cord-022526-j9kg00qf 3332 32 performance performance NN cord-022526-j9kg00qf 3332 33 . . . cord-022526-j9kg00qf 3333 1 Parenteral Parenteral NNP cord-022526-j9kg00qf 3333 2 administration administration NN cord-022526-j9kg00qf 3333 3 of of IN cord-022526-j9kg00qf 3333 4 dexamethasone dexamethasone NNP cord-022526-j9kg00qf 3333 5 sodium sodium NN cord-022526-j9kg00qf 3333 6 phosphate phosphate NN cord-022526-j9kg00qf 3333 7 was be VBD cord-022526-j9kg00qf 3333 8 tapered taper VBN cord-022526-j9kg00qf 3333 9 to to TO cord-022526-j9kg00qf 3333 10 achieve achieve VB cord-022526-j9kg00qf 3333 11 a a DT cord-022526-j9kg00qf 3333 12 minimal minimal JJ cord-022526-j9kg00qf 3333 13 effective effective JJ cord-022526-j9kg00qf 3333 14 dose dose NN cord-022526-j9kg00qf 3333 15 to to TO cord-022526-j9kg00qf 3333 16 reduce reduce VB cord-022526-j9kg00qf 3333 17 intestinal intestinal JJ cord-022526-j9kg00qf 3333 18 inflammation inflammation NN cord-022526-j9kg00qf 3333 19 and and CC cord-022526-j9kg00qf 3333 20 abolish abolish VB cord-022526-j9kg00qf 3333 21 clinical clinical JJ cord-022526-j9kg00qf 3333 22 signs sign NNS cord-022526-j9kg00qf 3333 23 . . . cord-022526-j9kg00qf 3334 1 Adverse adverse JJ cord-022526-j9kg00qf 3334 2 effects effect NNS cord-022526-j9kg00qf 3334 3 were be VBD cord-022526-j9kg00qf 3334 4 not not RB cord-022526-j9kg00qf 3334 5 reported report VBN cord-022526-j9kg00qf 3334 6 . . . cord-022526-j9kg00qf 3335 1 The the DT cord-022526-j9kg00qf 3335 2 outcome outcome NN cord-022526-j9kg00qf 3335 3 of of IN cord-022526-j9kg00qf 3335 4 this this DT cord-022526-j9kg00qf 3335 5 single single JJ cord-022526-j9kg00qf 3335 6 case case NN cord-022526-j9kg00qf 3335 7 is be VBZ cord-022526-j9kg00qf 3335 8 encouraging encouraging JJ cord-022526-j9kg00qf 3335 9 . . . cord-022526-j9kg00qf 3336 1 Surgery surgery NN cord-022526-j9kg00qf 3336 2 may may MD cord-022526-j9kg00qf 3336 3 be be VB cord-022526-j9kg00qf 3336 4 indicated indicate VBN cord-022526-j9kg00qf 3336 5 if if IN cord-022526-j9kg00qf 3336 6 the the DT cord-022526-j9kg00qf 3336 7 disease disease NN cord-022526-j9kg00qf 3336 8 is be VBZ cord-022526-j9kg00qf 3336 9 localized localize VBN cord-022526-j9kg00qf 3336 10 . . . cord-022526-j9kg00qf 3337 1 Two two CD cord-022526-j9kg00qf 3337 2 young young JJ cord-022526-j9kg00qf 3337 3 horses horse NNS cord-022526-j9kg00qf 3337 4 underwent undergo VBD cord-022526-j9kg00qf 3337 5 resection resection NN cord-022526-j9kg00qf 3337 6 of of IN cord-022526-j9kg00qf 3337 7 the the DT cord-022526-j9kg00qf 3337 8 thickened thickened JJ cord-022526-j9kg00qf 3337 9 terminal terminal JJ cord-022526-j9kg00qf 3337 10 small small JJ cord-022526-j9kg00qf 3337 11 intestine intestine NN cord-022526-j9kg00qf 3337 12 to to TO cord-022526-j9kg00qf 3337 13 confirm confirm VB cord-022526-j9kg00qf 3337 14 a a DT cord-022526-j9kg00qf 3337 15 diagnosis diagnosis NN cord-022526-j9kg00qf 3337 16 and and CC cord-022526-j9kg00qf 3337 17 provide provide VB cord-022526-j9kg00qf 3337 18 a a DT cord-022526-j9kg00qf 3337 19 means means NN cord-022526-j9kg00qf 3337 20 of of IN cord-022526-j9kg00qf 3337 21 treatment treatment NN cord-022526-j9kg00qf 3337 22 ; ; : cord-022526-j9kg00qf 3337 23 one one CD cord-022526-j9kg00qf 3337 24 horse horse NN cord-022526-j9kg00qf 3337 25 died die VBD cord-022526-j9kg00qf 3337 26 4 4 CD cord-022526-j9kg00qf 3337 27 months month NNS cord-022526-j9kg00qf 3337 28 after after IN cord-022526-j9kg00qf 3337 29 surgery surgery NN cord-022526-j9kg00qf 3337 30 , , , cord-022526-j9kg00qf 3337 31 and and CC cord-022526-j9kg00qf 3337 32 the the DT cord-022526-j9kg00qf 3337 33 other other JJ cord-022526-j9kg00qf 3337 34 has have VBZ cord-022526-j9kg00qf 3337 35 remained remain VBN cord-022526-j9kg00qf 3337 36 clinically clinically RB cord-022526-j9kg00qf 3337 37 normal normal JJ cord-022526-j9kg00qf 3337 38 for for IN cord-022526-j9kg00qf 3337 39 at at RB cord-022526-j9kg00qf 3337 40 least least RBS cord-022526-j9kg00qf 3337 41 10 10 CD cord-022526-j9kg00qf 3337 42 years year NNS cord-022526-j9kg00qf 3337 43 . . . cord-022526-j9kg00qf 3338 1 10 10 CD cord-022526-j9kg00qf 3339 1 The the DT cord-022526-j9kg00qf 3339 2 cause cause NN cord-022526-j9kg00qf 3339 3 of of IN cord-022526-j9kg00qf 3339 4 granulomatous granulomatous JJ cord-022526-j9kg00qf 3339 5 enteritis enteritis NN cord-022526-j9kg00qf 3339 6 is be VBZ cord-022526-j9kg00qf 3339 7 unknown unknown JJ cord-022526-j9kg00qf 3339 8 . . . cord-022526-j9kg00qf 3340 1 Several several JJ cord-022526-j9kg00qf 3340 2 infectious infectious JJ cord-022526-j9kg00qf 3340 3 agents agent NNS cord-022526-j9kg00qf 3340 4 have have VBP cord-022526-j9kg00qf 3340 5 been be VBN cord-022526-j9kg00qf 3340 6 implicated implicate VBN cord-022526-j9kg00qf 3340 7 , , , cord-022526-j9kg00qf 3340 8 including include VBG cord-022526-j9kg00qf 3340 9 Mycobacterium Mycobacterium NNP cord-022526-j9kg00qf 3340 10 avium avium NN cord-022526-j9kg00qf 3340 11 . . . cord-022526-j9kg00qf 3341 1 15 15 CD cord-022526-j9kg00qf 3342 1 The the DT cord-022526-j9kg00qf 3342 2 condition condition NN cord-022526-j9kg00qf 3342 3 may may MD cord-022526-j9kg00qf 3342 4 represent represent VB cord-022526-j9kg00qf 3342 5 a a DT cord-022526-j9kg00qf 3342 6 granulomatous granulomatous JJ cord-022526-j9kg00qf 3342 7 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 3342 8 reaction reaction NN cord-022526-j9kg00qf 3342 9 . . . cord-022526-j9kg00qf 3343 1 Immunemediated immunemediate VBN cord-022526-j9kg00qf 3343 2 responses response NNS cord-022526-j9kg00qf 3343 3 to to IN cord-022526-j9kg00qf 3343 4 dietary dietary JJ cord-022526-j9kg00qf 3343 5 , , , cord-022526-j9kg00qf 3343 6 parasitic parasitic JJ cord-022526-j9kg00qf 3343 7 , , , cord-022526-j9kg00qf 3343 8 or or CC cord-022526-j9kg00qf 3343 9 bacterial bacterial JJ cord-022526-j9kg00qf 3343 10 antigens antigen NNS cord-022526-j9kg00qf 3343 11 may may MD cord-022526-j9kg00qf 3343 12 be be VB cord-022526-j9kg00qf 3343 13 important important JJ cord-022526-j9kg00qf 3343 14 initiating initiate VBG cord-022526-j9kg00qf 3343 15 factors factor NNS cord-022526-j9kg00qf 3343 16 . . . cord-022526-j9kg00qf 3344 1 1 1 LS cord-022526-j9kg00qf 3345 1 Recently recently RB cord-022526-j9kg00qf 3345 2 , , , cord-022526-j9kg00qf 3345 3 six six CD cord-022526-j9kg00qf 3345 4 cases case NNS cord-022526-j9kg00qf 3345 5 purported purport VBN cord-022526-j9kg00qf 3345 6 to to TO cord-022526-j9kg00qf 3345 7 represent represent VB cord-022526-j9kg00qf 3345 8 granulomatous granulomatous JJ cord-022526-j9kg00qf 3345 9 enteritis enteritis NN cord-022526-j9kg00qf 3345 10 were be VBD cord-022526-j9kg00qf 3345 11 linked link VBN cord-022526-j9kg00qf 3345 12 to to IN cord-022526-j9kg00qf 3345 13 environmental environmental JJ cord-022526-j9kg00qf 3345 14 contamination contamination NN cord-022526-j9kg00qf 3345 15 with with IN cord-022526-j9kg00qf 3345 16 aluminum aluminum NN cord-022526-j9kg00qf 3345 17 . . . cord-022526-j9kg00qf 3346 1 16 16 CD cord-022526-j9kg00qf 3347 1 Although although IN cord-022526-j9kg00qf 3347 2 the the DT cord-022526-j9kg00qf 3347 3 case case NN cord-022526-j9kg00qf 3347 4 definition definition NN cord-022526-j9kg00qf 3347 5 was be VBD cord-022526-j9kg00qf 3347 6 flawed flaw VBN cord-022526-j9kg00qf 3347 7 and and CC cord-022526-j9kg00qf 3347 8 problems problem NNS cord-022526-j9kg00qf 3347 9 existed exist VBN cord-022526-j9kg00qf 3347 10 with with IN cord-022526-j9kg00qf 3347 11 the the DT cord-022526-j9kg00qf 3347 12 data datum NNS cord-022526-j9kg00qf 3347 13 and and CC cord-022526-j9kg00qf 3347 14 interpretation interpretation NN cord-022526-j9kg00qf 3347 15 , , , cord-022526-j9kg00qf 3347 16 17 17 CD cord-022526-j9kg00qf 3347 17 the the DT cord-022526-j9kg00qf 3347 18 report report NN cord-022526-j9kg00qf 3347 19 nevertheless nevertheless RB cord-022526-j9kg00qf 3347 20 raised raise VBD cord-022526-j9kg00qf 3347 21 the the DT cord-022526-j9kg00qf 3347 22 possibility possibility NN cord-022526-j9kg00qf 3347 23 that that IN cord-022526-j9kg00qf 3347 24 a a DT cord-022526-j9kg00qf 3347 25 toxicologic toxicologic JJ cord-022526-j9kg00qf 3347 26 basis basis NN cord-022526-j9kg00qf 3347 27 may may MD cord-022526-j9kg00qf 3347 28 exist exist VB cord-022526-j9kg00qf 3347 29 for for IN cord-022526-j9kg00qf 3347 30 some some DT cord-022526-j9kg00qf 3347 31 equine equine JJ cord-022526-j9kg00qf 3347 32 inflammatory inflammatory JJ cord-022526-j9kg00qf 3347 33 bowel bowel NN cord-022526-j9kg00qf 3347 34 disorders disorder NNS cord-022526-j9kg00qf 3347 35 . . . cord-022526-j9kg00qf 3348 1 lumen lumen NN cord-022526-j9kg00qf 3348 2 from from IN cord-022526-j9kg00qf 3348 3 parasitic parasitic JJ cord-022526-j9kg00qf 3348 4 , , , cord-022526-j9kg00qf 3348 5 bacterial bacterial JJ cord-022526-j9kg00qf 3348 6 , , , cord-022526-j9kg00qf 3348 7 or or CC cord-022526-j9kg00qf 3348 8 dietary dietary JJ cord-022526-j9kg00qf 3348 9 sources source NNS cord-022526-j9kg00qf 3348 10 . . . cord-022526-j9kg00qf 3349 1 Infectious infectious JJ cord-022526-j9kg00qf 3349 2 agents agent NNS cord-022526-j9kg00qf 3349 3 have have VBP cord-022526-j9kg00qf 3349 4 not not RB cord-022526-j9kg00qf 3349 5 been be VBN cord-022526-j9kg00qf 3349 6 identified identify VBN cord-022526-j9kg00qf 3349 7 . . . cord-022526-j9kg00qf 3350 1 18 18 CD cord-022526-j9kg00qf 3350 2 , , , cord-022526-j9kg00qf 3350 3 19 19 CD cord-022526-j9kg00qf 3350 4 Widespread widespread JJ cord-022526-j9kg00qf 3350 5 use use NN cord-022526-j9kg00qf 3350 6 of of IN cord-022526-j9kg00qf 3350 7 the the DT cord-022526-j9kg00qf 3350 8 avermectins avermectin NNS cord-022526-j9kg00qf 3350 9 has have VBZ cord-022526-j9kg00qf 3350 10 tended tend VBN cord-022526-j9kg00qf 3350 11 to to TO cord-022526-j9kg00qf 3350 12 reduce reduce VB cord-022526-j9kg00qf 3350 13 parasite parasite NN cord-022526-j9kg00qf 3350 14 loads load NNS cord-022526-j9kg00qf 3350 15 and and CC cord-022526-j9kg00qf 3350 16 composition composition NN cord-022526-j9kg00qf 3350 17 to to TO cord-022526-j9kg00qf 3350 18 favor favor VB cord-022526-j9kg00qf 3350 19 small small JJ cord-022526-j9kg00qf 3350 20 strongyles strongyle NNS cord-022526-j9kg00qf 3350 21 ( ( -LRB- cord-022526-j9kg00qf 3350 22 cyathostomes cyathostomes NNP cord-022526-j9kg00qf 3350 23 ) ) -RRB- cord-022526-j9kg00qf 3350 24 . . . cord-022526-j9kg00qf 3351 1 Eosinophilia Eosinophilia NNP cord-022526-j9kg00qf 3351 2 is be VBZ cord-022526-j9kg00qf 3351 3 a a DT cord-022526-j9kg00qf 3351 4 feature feature NN cord-022526-j9kg00qf 3351 5 of of IN cord-022526-j9kg00qf 3351 6 parasitism parasitism NN cord-022526-j9kg00qf 3351 7 in in IN cord-022526-j9kg00qf 3351 8 the the DT cord-022526-j9kg00qf 3351 9 equine equine JJ cord-022526-j9kg00qf 3351 10 intestinal intestinal JJ cord-022526-j9kg00qf 3351 11 tract tract NN cord-022526-j9kg00qf 3351 12 , , , cord-022526-j9kg00qf 3351 13 although although IN cord-022526-j9kg00qf 3351 14 nematodes nematode NNS cord-022526-j9kg00qf 3351 15 rarely rarely RB cord-022526-j9kg00qf 3351 16 have have VBP cord-022526-j9kg00qf 3351 17 been be VBN cord-022526-j9kg00qf 3351 18 identified identify VBN cord-022526-j9kg00qf 3351 19 in in IN cord-022526-j9kg00qf 3351 20 any any DT cord-022526-j9kg00qf 3351 21 lesions lesion NNS cord-022526-j9kg00qf 3351 22 of of IN cord-022526-j9kg00qf 3351 23 MEED MEED NNP cord-022526-j9kg00qf 3351 24 . . . cord-022526-j9kg00qf 3352 1 3 3 CD cord-022526-j9kg00qf 3352 2 , , , cord-022526-j9kg00qf 3352 3 18 18 CD cord-022526-j9kg00qf 3353 1 However however RB cord-022526-j9kg00qf 3353 2 , , , cord-022526-j9kg00qf 3353 3 failure failure NN cord-022526-j9kg00qf 3353 4 to to TO cord-022526-j9kg00qf 3353 5 detect detect VB cord-022526-j9kg00qf 3353 6 larval larval JJ cord-022526-j9kg00qf 3353 7 structures structure NNS cord-022526-j9kg00qf 3353 8 in in IN cord-022526-j9kg00qf 3353 9 these these DT cord-022526-j9kg00qf 3353 10 lesions lesion NNS cord-022526-j9kg00qf 3353 11 may may MD cord-022526-j9kg00qf 3353 12 be be VB cord-022526-j9kg00qf 3353 13 attributable attributable JJ cord-022526-j9kg00qf 3353 14 to to IN cord-022526-j9kg00qf 3353 15 chronicity chronicity NN cord-022526-j9kg00qf 3353 16 of of IN cord-022526-j9kg00qf 3353 17 the the DT cord-022526-j9kg00qf 3353 18 disease disease NN cord-022526-j9kg00qf 3353 19 and and CC cord-022526-j9kg00qf 3353 20 destruction destruction NN cord-022526-j9kg00qf 3353 21 of of IN cord-022526-j9kg00qf 3353 22 the the DT cord-022526-j9kg00qf 3353 23 parasites parasite NNS cord-022526-j9kg00qf 3353 24 in in IN cord-022526-j9kg00qf 3353 25 tissue tissue NN cord-022526-j9kg00qf 3353 26 . . . cord-022526-j9kg00qf 3354 1 10 10 CD cord-022526-j9kg00qf 3354 2 Biopsies biopsy NNS cord-022526-j9kg00qf 3354 3 of of IN cord-022526-j9kg00qf 3354 4 the the DT cord-022526-j9kg00qf 3354 5 rectal rectal JJ cord-022526-j9kg00qf 3354 6 mucosa mucosa JJ cord-022526-j9kg00qf 3354 7 12 12 CD cord-022526-j9kg00qf 3354 8 or or CC cord-022526-j9kg00qf 3354 9 of of IN cord-022526-j9kg00qf 3354 10 the the DT cord-022526-j9kg00qf 3354 11 skin skin NN cord-022526-j9kg00qf 3354 12 , , , cord-022526-j9kg00qf 3354 13 liver liver NN cord-022526-j9kg00qf 3354 14 , , , cord-022526-j9kg00qf 3354 15 intestinal intestinal JJ cord-022526-j9kg00qf 3354 16 tract tract NN cord-022526-j9kg00qf 3354 17 , , , cord-022526-j9kg00qf 3354 18 and and CC cord-022526-j9kg00qf 3354 19 lymph lymph NN cord-022526-j9kg00qf 3354 20 nodes node NNS cord-022526-j9kg00qf 3354 21 may may MD cord-022526-j9kg00qf 3354 22 assist assist VB cord-022526-j9kg00qf 3354 23 in in IN cord-022526-j9kg00qf 3354 24 diagnosis diagnosis NN cord-022526-j9kg00qf 3354 25 . . . cord-022526-j9kg00qf 3355 1 Treatment treatment NN cord-022526-j9kg00qf 3355 2 has have VBZ cord-022526-j9kg00qf 3355 3 been be VBN cord-022526-j9kg00qf 3355 4 attempted attempt VBN cord-022526-j9kg00qf 3355 5 with with IN cord-022526-j9kg00qf 3355 6 a a DT cord-022526-j9kg00qf 3355 7 variety variety NN cord-022526-j9kg00qf 3355 8 of of IN cord-022526-j9kg00qf 3355 9 drugs drug NNS cord-022526-j9kg00qf 3355 10 , , , cord-022526-j9kg00qf 3355 11 including include VBG cord-022526-j9kg00qf 3355 12 antibiotics antibiotic NNS cord-022526-j9kg00qf 3355 13 , , , cord-022526-j9kg00qf 3355 14 corticosteroids corticosteroid NNS cord-022526-j9kg00qf 3355 15 , , , cord-022526-j9kg00qf 3355 16 and and CC cord-022526-j9kg00qf 3355 17 anthelmintics anthelmintic NNS cord-022526-j9kg00qf 3355 18 with with IN cord-022526-j9kg00qf 3355 19 larvicidal larvicidal NNP cord-022526-j9kg00qf 3355 20 activity activity NN cord-022526-j9kg00qf 3355 21 . . . cord-022526-j9kg00qf 3356 1 Immediate immediate JJ cord-022526-j9kg00qf 3356 2 improvement improvement NN cord-022526-j9kg00qf 3356 3 has have VBZ cord-022526-j9kg00qf 3356 4 not not RB cord-022526-j9kg00qf 3356 5 been be VBN cord-022526-j9kg00qf 3356 6 borne bear VBN cord-022526-j9kg00qf 3356 7 out out RP cord-022526-j9kg00qf 3356 8 in in IN cord-022526-j9kg00qf 3356 9 the the DT cord-022526-j9kg00qf 3356 10 long long JJ cord-022526-j9kg00qf 3356 11 term term NN cord-022526-j9kg00qf 3356 12 . . . cord-022526-j9kg00qf 3357 1 Prognosis prognosis NN cord-022526-j9kg00qf 3357 2 is be VBZ cord-022526-j9kg00qf 3357 3 poor poor JJ cord-022526-j9kg00qf 3357 4 . . . cord-022526-j9kg00qf 3358 1 The the DT cord-022526-j9kg00qf 3358 2 clinical clinical JJ cord-022526-j9kg00qf 3358 3 objective objective NN cord-022526-j9kg00qf 3358 4 is be VBZ cord-022526-j9kg00qf 3358 5 to to TO cord-022526-j9kg00qf 3358 6 reach reach VB cord-022526-j9kg00qf 3358 7 a a DT cord-022526-j9kg00qf 3358 8 tentative tentative JJ cord-022526-j9kg00qf 3358 9 diagnosis diagnosis NN cord-022526-j9kg00qf 3358 10 early early RB cord-022526-j9kg00qf 3358 11 in in IN cord-022526-j9kg00qf 3358 12 the the DT cord-022526-j9kg00qf 3358 13 course course NN cord-022526-j9kg00qf 3358 14 of of IN cord-022526-j9kg00qf 3358 15 the the DT cord-022526-j9kg00qf 3358 16 disease disease NN cord-022526-j9kg00qf 3358 17 for for IN cord-022526-j9kg00qf 3358 18 intervention intervention NN cord-022526-j9kg00qf 3358 19 to to TO cord-022526-j9kg00qf 3358 20 be be VB cord-022526-j9kg00qf 3358 21 more more JJR cord-022526-j9kg00qf 3358 22 than than IN cord-022526-j9kg00qf 3358 23 transient transient JJ cord-022526-j9kg00qf 3358 24 . . . cord-022526-j9kg00qf 3359 1 Unlike unlike IN cord-022526-j9kg00qf 3359 2 the the DT cord-022526-j9kg00qf 3359 3 other other JJ cord-022526-j9kg00qf 3359 4 conditions condition NNS cord-022526-j9kg00qf 3359 5 ( ( -LRB- cord-022526-j9kg00qf 3359 6 see see VB cord-022526-j9kg00qf 3359 7 Table Table NNP cord-022526-j9kg00qf 3359 8 13 13 CD cord-022526-j9kg00qf 3359 9 .12 .12 CD cord-022526-j9kg00qf 3359 10 - - SYM cord-022526-j9kg00qf 3359 11 1 1 CD cord-022526-j9kg00qf 3359 12 ) ) -RRB- cord-022526-j9kg00qf 3359 13 , , , cord-022526-j9kg00qf 3359 14 MEED MEED NNP cord-022526-j9kg00qf 3359 15 has have VBZ cord-022526-j9kg00qf 3359 16 definitive definitive JJ cord-022526-j9kg00qf 3359 17 liver liver NN cord-022526-j9kg00qf 3359 18 and and CC cord-022526-j9kg00qf 3359 19 pancreatic pancreatic NN cord-022526-j9kg00qf 3359 20 involvement involvement NN cord-022526-j9kg00qf 3359 21 , , , cord-022526-j9kg00qf 3359 22 and and CC cord-022526-j9kg00qf 3359 23 thus thus RB cord-022526-j9kg00qf 3359 24 maldigestion maldigestion NNP cord-022526-j9kg00qf 3359 25 may may MD cord-022526-j9kg00qf 3359 26 make make VB cord-022526-j9kg00qf 3359 27 a a DT cord-022526-j9kg00qf 3359 28 significant significant JJ cord-022526-j9kg00qf 3359 29 contribution contribution NN cord-022526-j9kg00qf 3359 30 to to IN cord-022526-j9kg00qf 3359 31 the the DT cord-022526-j9kg00qf 3359 32 wasting waste VBG cord-022526-j9kg00qf 3359 33 disease disease NN cord-022526-j9kg00qf 3359 34 . . . cord-022526-j9kg00qf 3360 1 For for IN cord-022526-j9kg00qf 3360 2 example example NN cord-022526-j9kg00qf 3360 3 , , , cord-022526-j9kg00qf 3360 4 the the DT cord-022526-j9kg00qf 3360 5 lowered lower VBN cord-022526-j9kg00qf 3360 6 albumin albumin NN cord-022526-j9kg00qf 3360 7 and and CC cord-022526-j9kg00qf 3360 8 protein protein NN cord-022526-j9kg00qf 3360 9 could could MD cord-022526-j9kg00qf 3360 10 result result VB cord-022526-j9kg00qf 3360 11 in in IN cord-022526-j9kg00qf 3360 12 part part NN cord-022526-j9kg00qf 3360 13 from from IN cord-022526-j9kg00qf 3360 14 impaired impaired JJ cord-022526-j9kg00qf 3360 15 pancreatic pancreatic JJ cord-022526-j9kg00qf 3360 16 enzyme enzyme NN cord-022526-j9kg00qf 3360 17 digestion digestion NN cord-022526-j9kg00qf 3360 18 , , , cord-022526-j9kg00qf 3360 19 and and CC cord-022526-j9kg00qf 3360 20 the the DT cord-022526-j9kg00qf 3360 21 effects effect NNS cord-022526-j9kg00qf 3360 22 of of IN cord-022526-j9kg00qf 3360 23 inflammatory inflammatory JJ cord-022526-j9kg00qf 3360 24 lesions lesion NNS cord-022526-j9kg00qf 3360 25 in in IN cord-022526-j9kg00qf 3360 26 the the DT cord-022526-j9kg00qf 3360 27 liver liver NN cord-022526-j9kg00qf 3360 28 and and CC cord-022526-j9kg00qf 3360 29 ileum ileum NN cord-022526-j9kg00qf 3360 30 may may MD cord-022526-j9kg00qf 3360 31 decrease decrease VB cord-022526-j9kg00qf 3360 32 bile bile NN cord-022526-j9kg00qf 3360 33 salt salt NN cord-022526-j9kg00qf 3360 34 concentrations concentration NNS cord-022526-j9kg00qf 3360 35 . . . cord-022526-j9kg00qf 3361 1 The the DT cord-022526-j9kg00qf 3361 2 morphologic morphologic JJ cord-022526-j9kg00qf 3361 3 findings finding NNS cord-022526-j9kg00qf 3361 4 in in IN cord-022526-j9kg00qf 3361 5 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 3361 6 - - HYPH cord-022526-j9kg00qf 3361 7 plasmacytic plasmacytic JJ cord-022526-j9kg00qf 3361 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3361 9 reflect reflect VBP cord-022526-j9kg00qf 3361 10 the the DT cord-022526-j9kg00qf 3361 11 predominant predominant JJ cord-022526-j9kg00qf 3361 12 infiltrative infiltrative JJ cord-022526-j9kg00qf 3361 13 cellular cellular JJ cord-022526-j9kg00qf 3361 14 elements element NNS cord-022526-j9kg00qf 3361 15 of of IN cord-022526-j9kg00qf 3361 16 this this DT cord-022526-j9kg00qf 3361 17 rarely rarely RB cord-022526-j9kg00qf 3361 18 encountered encounter VBD cord-022526-j9kg00qf 3361 19 condition condition NN cord-022526-j9kg00qf 3361 20 . . . cord-022526-j9kg00qf 3362 1 A a DT cord-022526-j9kg00qf 3362 2 retrospective retrospective JJ cord-022526-j9kg00qf 3362 3 study study NN cord-022526-j9kg00qf 3362 4 of of IN cord-022526-j9kg00qf 3362 5 14 14 CD cord-022526-j9kg00qf 3362 6 horses horse NNS cord-022526-j9kg00qf 3362 7 23 23 CD cord-022526-j9kg00qf 3362 8 provided provide VBD cord-022526-j9kg00qf 3362 9 the the DT cord-022526-j9kg00qf 3362 10 information information NN cord-022526-j9kg00qf 3362 11 presented present VBN cord-022526-j9kg00qf 3362 12 in in IN cord-022526-j9kg00qf 3362 13 the the DT cord-022526-j9kg00qf 3362 14 tables table NNS cord-022526-j9kg00qf 3362 15 . . . cord-022526-j9kg00qf 3363 1 No no DT cord-022526-j9kg00qf 3363 2 specific specific JJ cord-022526-j9kg00qf 3363 3 clinical clinical JJ cord-022526-j9kg00qf 3363 4 or or CC cord-022526-j9kg00qf 3363 5 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 3363 6 features feature NNS cord-022526-j9kg00qf 3363 7 differentiate differentiate VBP cord-022526-j9kg00qf 3363 8 this this DT cord-022526-j9kg00qf 3363 9 condition condition NN cord-022526-j9kg00qf 3363 10 antemortem antemortem NN cord-022526-j9kg00qf 3363 11 from from IN cord-022526-j9kg00qf 3363 12 other other JJ cord-022526-j9kg00qf 3363 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 3363 14 diseases disease NNS cord-022526-j9kg00qf 3363 15 of of IN cord-022526-j9kg00qf 3363 16 adult adult NN cord-022526-j9kg00qf 3363 17 horses horse NNS cord-022526-j9kg00qf 3363 18 . . . cord-022526-j9kg00qf 3364 1 Carbohydrate carbohydrate NN cord-022526-j9kg00qf 3364 2 absorption absorption NN cord-022526-j9kg00qf 3364 3 was be VBD cord-022526-j9kg00qf 3364 4 abnormal abnormal JJ cord-022526-j9kg00qf 3364 5 or or CC cord-022526-j9kg00qf 3364 6 delayed delay VBN cord-022526-j9kg00qf 3364 7 in in IN cord-022526-j9kg00qf 3364 8 9 9 CD cord-022526-j9kg00qf 3364 9 of of IN cord-022526-j9kg00qf 3364 10 12 12 CD cord-022526-j9kg00qf 3364 11 horses horse NNS cord-022526-j9kg00qf 3364 12 , , , cord-022526-j9kg00qf 3364 13 consistent consistent JJ cord-022526-j9kg00qf 3364 14 with with IN cord-022526-j9kg00qf 3364 15 the the DT cord-022526-j9kg00qf 3364 16 predominance predominance NN cord-022526-j9kg00qf 3364 17 of of IN cord-022526-j9kg00qf 3364 18 small small JJ cord-022526-j9kg00qf 3364 19 intestinal intestinal JJ cord-022526-j9kg00qf 3364 20 pathologic pathologic JJ cord-022526-j9kg00qf 3364 21 changes change NNS cord-022526-j9kg00qf 3364 22 . . . cord-022526-j9kg00qf 3365 1 Rectal rectal JJ cord-022526-j9kg00qf 3365 2 biopsies biopsy NNS cord-022526-j9kg00qf 3365 3 were be VBD cord-022526-j9kg00qf 3365 4 abnormal abnormal JJ cord-022526-j9kg00qf 3365 5 in in IN cord-022526-j9kg00qf 3365 6 3 3 CD cord-022526-j9kg00qf 3365 7 of of IN cord-022526-j9kg00qf 3365 8 7 7 CD cord-022526-j9kg00qf 3365 9 horses horse NNS cord-022526-j9kg00qf 3365 10 , , , cord-022526-j9kg00qf 3365 11 two two CD cord-022526-j9kg00qf 3365 12 of of IN cord-022526-j9kg00qf 3365 13 which which WDT cord-022526-j9kg00qf 3365 14 were be VBD cord-022526-j9kg00qf 3365 15 reported report VBN cord-022526-j9kg00qf 3365 16 as as IN cord-022526-j9kg00qf 3365 17 having have VBG cord-022526-j9kg00qf 3365 18 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 3365 19 - - HYPH cord-022526-j9kg00qf 3365 20 plasmacytic plasmacytic JJ cord-022526-j9kg00qf 3365 21 proctitis proctitis NN cord-022526-j9kg00qf 3365 22 . . . cord-022526-j9kg00qf 3366 1 Prognosis prognosis NN cord-022526-j9kg00qf 3366 2 is be VBZ cord-022526-j9kg00qf 3366 3 poor poor JJ cord-022526-j9kg00qf 3366 4 . . . cord-022526-j9kg00qf 3367 1 Treatment treatment NN cord-022526-j9kg00qf 3367 2 has have VBZ cord-022526-j9kg00qf 3367 3 been be VBN cord-022526-j9kg00qf 3367 4 unsuccessful unsuccessful JJ cord-022526-j9kg00qf 3367 5 , , , cord-022526-j9kg00qf 3367 6 probably probably RB cord-022526-j9kg00qf 3367 7 because because IN cord-022526-j9kg00qf 3367 8 of of IN cord-022526-j9kg00qf 3367 9 the the DT cord-022526-j9kg00qf 3367 10 advanced advanced JJ cord-022526-j9kg00qf 3367 11 nature nature NN cord-022526-j9kg00qf 3367 12 of of IN cord-022526-j9kg00qf 3367 13 the the DT cord-022526-j9kg00qf 3367 14 condition condition NN cord-022526-j9kg00qf 3367 15 at at IN cord-022526-j9kg00qf 3367 16 the the DT cord-022526-j9kg00qf 3367 17 beginning beginning NN cord-022526-j9kg00qf 3367 18 of of IN cord-022526-j9kg00qf 3367 19 treatment treatment NN cord-022526-j9kg00qf 3367 20 . . . cord-022526-j9kg00qf 3368 1 Proliferative Proliferative NNP cord-022526-j9kg00qf 3368 2 enteropathy enteropathy NNP cord-022526-j9kg00qf 3368 3 has have VBZ cord-022526-j9kg00qf 3368 4 not not RB cord-022526-j9kg00qf 3368 5 been be VBN cord-022526-j9kg00qf 3368 6 associated associate VBN cord-022526-j9kg00qf 3368 7 with with IN cord-022526-j9kg00qf 3368 8 abnormal abnormal JJ cord-022526-j9kg00qf 3368 9 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3368 10 absorption absorption NN cord-022526-j9kg00qf 3368 11 based base VBN cord-022526-j9kg00qf 3368 12 on on IN cord-022526-j9kg00qf 3368 13 three three CD cord-022526-j9kg00qf 3368 14 horses horse NNS cord-022526-j9kg00qf 3368 15 subjected subject VBN cord-022526-j9kg00qf 3368 16 to to IN cord-022526-j9kg00qf 3368 17 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3368 18 absorption absorption NN cord-022526-j9kg00qf 3368 19 tests test NNS cord-022526-j9kg00qf 3368 20 . . . cord-022526-j9kg00qf 3369 1 However however RB cord-022526-j9kg00qf 3369 2 , , , cord-022526-j9kg00qf 3369 3 the the DT cord-022526-j9kg00qf 3369 4 florid florid JJ cord-022526-j9kg00qf 3369 5 mucosal mucosal JJ cord-022526-j9kg00qf 3369 6 lesions lesion NNS cord-022526-j9kg00qf 3369 7 in in IN cord-022526-j9kg00qf 3369 8 the the DT cord-022526-j9kg00qf 3369 9 jejunum jejunum NN cord-022526-j9kg00qf 3369 10 and and CC cord-022526-j9kg00qf 3369 11 ileum ileum NN cord-022526-j9kg00qf 3369 12 undoubtedly undoubtedly RB cord-022526-j9kg00qf 3369 13 contribute contribute VBP cord-022526-j9kg00qf 3369 14 to to IN cord-022526-j9kg00qf 3369 15 impaired impair VBN cord-022526-j9kg00qf 3369 16 digestive digestive JJ cord-022526-j9kg00qf 3369 17 function function NN cord-022526-j9kg00qf 3369 18 and and CC cord-022526-j9kg00qf 3369 19 potential potential JJ cord-022526-j9kg00qf 3369 20 malabsorption malabsorption NN cord-022526-j9kg00qf 3369 21 of of IN cord-022526-j9kg00qf 3369 22 vitamins vitamin NNS cord-022526-j9kg00qf 3369 23 , , , cord-022526-j9kg00qf 3369 24 minerals mineral NNS cord-022526-j9kg00qf 3369 25 , , , cord-022526-j9kg00qf 3369 26 and and CC cord-022526-j9kg00qf 3369 27 amino amino JJ cord-022526-j9kg00qf 3369 28 acids acid NNS cord-022526-j9kg00qf 3369 29 in in IN cord-022526-j9kg00qf 3369 30 the the DT cord-022526-j9kg00qf 3369 31 distal distal JJ cord-022526-j9kg00qf 3369 32 small small JJ cord-022526-j9kg00qf 3369 33 intestine intestine NN cord-022526-j9kg00qf 3369 34 . . . cord-022526-j9kg00qf 3370 1 The the DT cord-022526-j9kg00qf 3370 2 condition condition NN cord-022526-j9kg00qf 3370 3 MEED MEED NNP cord-022526-j9kg00qf 3370 4 encompasses encompass VBZ cord-022526-j9kg00qf 3370 5 disorders disorder NNS cord-022526-j9kg00qf 3370 6 characterized characterize VBN cord-022526-j9kg00qf 3370 7 by by IN cord-022526-j9kg00qf 3370 8 a a DT cord-022526-j9kg00qf 3370 9 predominant predominant JJ cord-022526-j9kg00qf 3370 10 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3370 11 infiltrate infiltrate NN cord-022526-j9kg00qf 3370 12 in in IN cord-022526-j9kg00qf 3370 13 the the DT cord-022526-j9kg00qf 3370 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3370 15 tract tract NN cord-022526-j9kg00qf 3370 16 , , , cord-022526-j9kg00qf 3370 17 associated associated JJ cord-022526-j9kg00qf 3370 18 lymph lymph NN cord-022526-j9kg00qf 3370 19 nodes node NNS cord-022526-j9kg00qf 3370 20 , , , cord-022526-j9kg00qf 3370 21 liver liver NN cord-022526-j9kg00qf 3370 22 , , , cord-022526-j9kg00qf 3370 23 pancreas pancrea NNS cord-022526-j9kg00qf 3370 24 , , , cord-022526-j9kg00qf 3370 25 skin skin NN cord-022526-j9kg00qf 3370 26 , , , cord-022526-j9kg00qf 3370 27 and and CC cord-022526-j9kg00qf 3370 28 other other JJ cord-022526-j9kg00qf 3370 29 structures structure NNS cord-022526-j9kg00qf 3370 30 and and CC cord-022526-j9kg00qf 3370 31 accompanied accompany VBN cord-022526-j9kg00qf 3370 32 by by IN cord-022526-j9kg00qf 3370 33 some some DT cord-022526-j9kg00qf 3370 34 degree degree NN cord-022526-j9kg00qf 3370 35 of of IN cord-022526-j9kg00qf 3370 36 malabsorption malabsorption NN cord-022526-j9kg00qf 3370 37 and and CC cord-022526-j9kg00qf 3370 38 enteric enteric JJ cord-022526-j9kg00qf 3370 39 protein protein NN cord-022526-j9kg00qf 3370 40 loss loss NN cord-022526-j9kg00qf 3370 41 . . . cord-022526-j9kg00qf 3371 1 The the DT cord-022526-j9kg00qf 3371 2 disorders disorder NNS cord-022526-j9kg00qf 3371 3 include include VBP cord-022526-j9kg00qf 3371 4 chronic chronic JJ cord-022526-j9kg00qf 3371 5 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3371 6 gastroenteritis gastroenteritis NN cord-022526-j9kg00qf 3371 7 , , , cord-022526-j9kg00qf 3371 8 18 18 CD cord-022526-j9kg00qf 3371 9 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3371 10 granulomatosis granulomatosis NN cord-022526-j9kg00qf 3371 11 , , , cord-022526-j9kg00qf 3371 12 9 9 CD cord-022526-j9kg00qf 3371 13 chronic chronic JJ cord-022526-j9kg00qf 3371 14 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3371 15 dermatitis dermatitis NN cord-022526-j9kg00qf 3371 16 , , , cord-022526-j9kg00qf 3371 17 19 19 CD cord-022526-j9kg00qf 3371 18 and and CC cord-022526-j9kg00qf 3371 19 probably probably RB cord-022526-j9kg00qf 3371 20 basophilic basophilic JJ cord-022526-j9kg00qf 3371 21 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3371 22 . . . cord-022526-j9kg00qf 3372 1 20 20 CD cord-022526-j9kg00qf 3373 1 The the DT cord-022526-j9kg00qf 3373 2 condition condition NN cord-022526-j9kg00qf 3373 3 differs differ VBZ cord-022526-j9kg00qf 3373 4 from from IN cord-022526-j9kg00qf 3373 5 idiopathic idiopathic JJ cord-022526-j9kg00qf 3373 6 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3373 7 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3373 8 , , , cord-022526-j9kg00qf 3373 9 10 10 CD cord-022526-j9kg00qf 3373 10 in in IN cord-022526-j9kg00qf 3373 11 which which WDT cord-022526-j9kg00qf 3373 12 segmental segmental JJ cord-022526-j9kg00qf 3373 13 lesions lesion NNS cord-022526-j9kg00qf 3373 14 in in IN cord-022526-j9kg00qf 3373 15 the the DT cord-022526-j9kg00qf 3373 16 small small JJ cord-022526-j9kg00qf 3373 17 or or CC cord-022526-j9kg00qf 3373 18 large large JJ cord-022526-j9kg00qf 3373 19 intestine intestine NN cord-022526-j9kg00qf 3373 20 induce induce NN cord-022526-j9kg00qf 3373 21 signs sign NNS cord-022526-j9kg00qf 3373 22 of of IN cord-022526-j9kg00qf 3373 23 colic colic NN cord-022526-j9kg00qf 3373 24 requiring require VBG cord-022526-j9kg00qf 3373 25 surgical surgical JJ cord-022526-j9kg00qf 3373 26 intervention intervention NN cord-022526-j9kg00qf 3373 27 21,22 21,22 CD cord-022526-j9kg00qf 3373 28 without without IN cord-022526-j9kg00qf 3373 29 evidence evidence NN cord-022526-j9kg00qf 3373 30 of of IN cord-022526-j9kg00qf 3373 31 malabsorption malabsorption NN cord-022526-j9kg00qf 3373 32 or or CC cord-022526-j9kg00qf 3373 33 multisystem multisystem JJ cord-022526-j9kg00qf 3373 34 involvement involvement NN cord-022526-j9kg00qf 3373 35 . . . cord-022526-j9kg00qf 3374 1 Although although IN cord-022526-j9kg00qf 3374 2 prevalence prevalence NN cord-022526-j9kg00qf 3374 3 is be VBZ cord-022526-j9kg00qf 3374 4 low low JJ cord-022526-j9kg00qf 3374 5 , , , cord-022526-j9kg00qf 3374 6 MEED MEED NNP cord-022526-j9kg00qf 3374 7 appears appear VBZ cord-022526-j9kg00qf 3374 8 to to TO cord-022526-j9kg00qf 3374 9 be be VB cord-022526-j9kg00qf 3374 10 more more RBR cord-022526-j9kg00qf 3374 11 common common JJ cord-022526-j9kg00qf 3374 12 than than IN cord-022526-j9kg00qf 3374 13 granulomatous granulomatous JJ cord-022526-j9kg00qf 3374 14 enteritis enteritis NN cord-022526-j9kg00qf 3374 15 based base VBN cord-022526-j9kg00qf 3374 16 on on IN cord-022526-j9kg00qf 3374 17 the the DT cord-022526-j9kg00qf 3374 18 accumulated accumulate VBN cord-022526-j9kg00qf 3374 19 published publish VBN cord-022526-j9kg00qf 3374 20 reports report NNS cord-022526-j9kg00qf 3374 21 and and CC cord-022526-j9kg00qf 3374 22 personal personal JJ cord-022526-j9kg00qf 3374 23 experience experience NN cord-022526-j9kg00qf 3374 24 in in IN cord-022526-j9kg00qf 3374 25 Australia Australia NNP cord-022526-j9kg00qf 3374 26 and and CC cord-022526-j9kg00qf 3374 27 the the DT cord-022526-j9kg00qf 3374 28 United United NNP cord-022526-j9kg00qf 3374 29 States States NNP cord-022526-j9kg00qf 3374 30 . . . cord-022526-j9kg00qf 3375 1 Most Most JJS cord-022526-j9kg00qf 3375 2 affected affected JJ cord-022526-j9kg00qf 3375 3 horses horse NNS cord-022526-j9kg00qf 3375 4 are be VBP cord-022526-j9kg00qf 3375 5 2 2 CD cord-022526-j9kg00qf 3375 6 to to IN cord-022526-j9kg00qf 3375 7 4 4 CD cord-022526-j9kg00qf 3375 8 years year NNS cord-022526-j9kg00qf 3375 9 of of IN cord-022526-j9kg00qf 3375 10 age age NN cord-022526-j9kg00qf 3375 11 , , , cord-022526-j9kg00qf 3375 12 and and CC cord-022526-j9kg00qf 3375 13 Standardbreds Standardbreds NNPS cord-022526-j9kg00qf 3375 14 and and CC cord-022526-j9kg00qf 3375 15 Thoroughbred Thoroughbred NNP cord-022526-j9kg00qf 3375 16 are be VBP cord-022526-j9kg00qf 3375 17 reported report VBN cord-022526-j9kg00qf 3375 18 to to TO cord-022526-j9kg00qf 3375 19 predominate predominate VB cord-022526-j9kg00qf 3375 20 . . . cord-022526-j9kg00qf 3376 1 The the DT cord-022526-j9kg00qf 3376 2 condition condition NN cord-022526-j9kg00qf 3376 3 is be VBZ cord-022526-j9kg00qf 3376 4 sporadic sporadic JJ cord-022526-j9kg00qf 3376 5 and and CC cord-022526-j9kg00qf 3376 6 has have VBZ cord-022526-j9kg00qf 3376 7 an an DT cord-022526-j9kg00qf 3376 8 insidious insidious JJ cord-022526-j9kg00qf 3376 9 onset onset NN cord-022526-j9kg00qf 3376 10 , , , cord-022526-j9kg00qf 3376 11 and and CC cord-022526-j9kg00qf 3376 12 the the DT cord-022526-j9kg00qf 3376 13 course course NN cord-022526-j9kg00qf 3376 14 is be VBZ cord-022526-j9kg00qf 3376 15 protracted protract VBN cord-022526-j9kg00qf 3376 16 with with IN cord-022526-j9kg00qf 3376 17 a a DT cord-022526-j9kg00qf 3376 18 duration duration NN cord-022526-j9kg00qf 3376 19 of of IN cord-022526-j9kg00qf 3376 20 1 1 CD cord-022526-j9kg00qf 3376 21 to to TO cord-022526-j9kg00qf 3376 22 10 10 CD cord-022526-j9kg00qf 3376 23 months month NNS cord-022526-j9kg00qf 3376 24 . . . cord-022526-j9kg00qf 3377 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3377 2 is be VBZ cord-022526-j9kg00qf 3377 3 common common JJ cord-022526-j9kg00qf 3377 4 in in IN cord-022526-j9kg00qf 3377 5 contrast contrast NN cord-022526-j9kg00qf 3377 6 to to IN cord-022526-j9kg00qf 3377 7 granulomatous granulomatous JJ cord-022526-j9kg00qf 3377 8 enteritis enteritis NN cord-022526-j9kg00qf 3377 9 . . . cord-022526-j9kg00qf 3378 1 Severe severe JJ cord-022526-j9kg00qf 3378 2 skin skin NN cord-022526-j9kg00qf 3378 3 lesions lesion NNS cord-022526-j9kg00qf 3378 4 with with IN cord-022526-j9kg00qf 3378 5 exudative exudative JJ cord-022526-j9kg00qf 3378 6 dermatitis dermatitis NN cord-022526-j9kg00qf 3378 7 and and CC cord-022526-j9kg00qf 3378 8 ulcerative ulcerative JJ cord-022526-j9kg00qf 3378 9 coronitis coronitis NNP cord-022526-j9kg00qf 3378 10 are be VBP cord-022526-j9kg00qf 3378 11 prominent prominent JJ cord-022526-j9kg00qf 3378 12 and and CC cord-022526-j9kg00qf 3378 13 frequently frequently RB cord-022526-j9kg00qf 3378 14 are be VBP cord-022526-j9kg00qf 3378 15 the the DT cord-022526-j9kg00qf 3378 16 principal principal JJ cord-022526-j9kg00qf 3378 17 reason reason NN cord-022526-j9kg00qf 3378 18 for for IN cord-022526-j9kg00qf 3378 19 veterinary veterinary JJ cord-022526-j9kg00qf 3378 20 attention attention NN cord-022526-j9kg00qf 3378 21 being be VBG cord-022526-j9kg00qf 3378 22 sought seek VBN cord-022526-j9kg00qf 3378 23 . . . cord-022526-j9kg00qf 3379 1 Despite despite IN cord-022526-j9kg00qf 3379 2 extensive extensive JJ cord-022526-j9kg00qf 3379 3 tissue tissue NN cord-022526-j9kg00qf 3379 4 eosinophilia eosinophilia NN cord-022526-j9kg00qf 3379 5 , , , cord-022526-j9kg00qf 3379 6 systemic systemic JJ cord-022526-j9kg00qf 3379 7 eosinophilia eosinophilia NN cord-022526-j9kg00qf 3379 8 is be VBZ cord-022526-j9kg00qf 3379 9 rare rare JJ cord-022526-j9kg00qf 3379 10 . . . cord-022526-j9kg00qf 3380 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 3380 2 values value NNS cord-022526-j9kg00qf 3380 3 are be VBP cord-022526-j9kg00qf 3380 4 usually usually RB cord-022526-j9kg00qf 3380 5 unremarkable unremarkable JJ cord-022526-j9kg00qf 3380 6 . . . cord-022526-j9kg00qf 3381 1 Notable notable JJ cord-022526-j9kg00qf 3381 2 features feature NNS cord-022526-j9kg00qf 3381 3 include include VBP cord-022526-j9kg00qf 3381 4 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3381 5 and and CC cord-022526-j9kg00qf 3381 6 normal normal JJ cord-022526-j9kg00qf 3381 7 serum serum NN cord-022526-j9kg00qf 3381 8 protein protein NN cord-022526-j9kg00qf 3381 9 or or CC cord-022526-j9kg00qf 3381 10 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 3381 11 , , , cord-022526-j9kg00qf 3381 12 and and CC cord-022526-j9kg00qf 3381 13 because because IN cord-022526-j9kg00qf 3381 14 of of IN cord-022526-j9kg00qf 3381 15 liver liver NN cord-022526-j9kg00qf 3381 16 involvement involvement NN cord-022526-j9kg00qf 3381 17 , , , cord-022526-j9kg00qf 3381 18 serum serum NN cord-022526-j9kg00qf 3381 19 γ γ NN cord-022526-j9kg00qf 3381 20 - - HYPH cord-022526-j9kg00qf 3381 21 glutamyltransferase glutamyltransferase NN cord-022526-j9kg00qf 3381 22 and and CC cord-022526-j9kg00qf 3381 23 alkaline alkaline JJ cord-022526-j9kg00qf 3381 24 phosphatase phosphatase NN cord-022526-j9kg00qf 3381 25 activities activity NNS cord-022526-j9kg00qf 3381 26 may may MD cord-022526-j9kg00qf 3381 27 be be VB cord-022526-j9kg00qf 3381 28 increased increase VBN cord-022526-j9kg00qf 3381 29 . . . cord-022526-j9kg00qf 3382 1 Most Most JJS cord-022526-j9kg00qf 3382 2 reports report NNS cord-022526-j9kg00qf 3382 3 of of IN cord-022526-j9kg00qf 3382 4 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3382 5 absorption absorption NN cord-022526-j9kg00qf 3382 6 test test NN cord-022526-j9kg00qf 3382 7 findings finding NNS cord-022526-j9kg00qf 3382 8 ( ( -LRB- cord-022526-j9kg00qf 3382 9 glucose glucose NN cord-022526-j9kg00qf 3382 10 or or CC cord-022526-j9kg00qf 3382 11 D d NN cord-022526-j9kg00qf 3382 12 - - HYPH cord-022526-j9kg00qf 3382 13 xylose xylose NNP cord-022526-j9kg00qf 3382 14 ) ) -RRB- cord-022526-j9kg00qf 3382 15 indicate indicate VBP cord-022526-j9kg00qf 3382 16 retarded retarded JJ cord-022526-j9kg00qf 3382 17 absorption absorption NN cord-022526-j9kg00qf 3382 18 and and CC cord-022526-j9kg00qf 3382 19 a a DT cord-022526-j9kg00qf 3382 20 reduced reduced JJ cord-022526-j9kg00qf 3382 21 or or CC cord-022526-j9kg00qf 3382 22 normal normal JJ cord-022526-j9kg00qf 3382 23 peak peak NN cord-022526-j9kg00qf 3382 24 concentration concentration NN cord-022526-j9kg00qf 3382 25 delayed delay VBN cord-022526-j9kg00qf 3382 26 to to IN cord-022526-j9kg00qf 3382 27 at at RB cord-022526-j9kg00qf 3382 28 least least RBS cord-022526-j9kg00qf 3382 29 180 180 CD cord-022526-j9kg00qf 3382 30 minutes minute NNS cord-022526-j9kg00qf 3382 31 . . . cord-022526-j9kg00qf 3383 1 One one PRP cord-022526-j9kg00qf 3383 2 can can MD cord-022526-j9kg00qf 3383 3 interpret interpret VB cord-022526-j9kg00qf 3383 4 this this DT cord-022526-j9kg00qf 3383 5 pattern pattern NN cord-022526-j9kg00qf 3383 6 as as IN cord-022526-j9kg00qf 3383 7 the the DT cord-022526-j9kg00qf 3383 8 existence existence NN cord-022526-j9kg00qf 3383 9 of of IN cord-022526-j9kg00qf 3383 10 sufficient sufficient JJ cord-022526-j9kg00qf 3383 11 small small JJ cord-022526-j9kg00qf 3383 12 intestinal intestinal JJ cord-022526-j9kg00qf 3383 13 absorptive absorptive JJ cord-022526-j9kg00qf 3383 14 capacity capacity NN cord-022526-j9kg00qf 3383 15 to to TO cord-022526-j9kg00qf 3383 16 enable enable VB cord-022526-j9kg00qf 3383 17 moderate moderate JJ cord-022526-j9kg00qf 3383 18 absorption absorption NN cord-022526-j9kg00qf 3383 19 with with IN cord-022526-j9kg00qf 3383 20 possibly possibly RB cord-022526-j9kg00qf 3383 21 delayed delayed JJ cord-022526-j9kg00qf 3383 22 gastric gastric JJ cord-022526-j9kg00qf 3383 23 emptying emptying NN cord-022526-j9kg00qf 3383 24 or or CC cord-022526-j9kg00qf 3383 25 ileocecal ileocecal JJ cord-022526-j9kg00qf 3383 26 ejection ejection NN cord-022526-j9kg00qf 3383 27 . . . cord-022526-j9kg00qf 3384 1 Morphologic morphologic JJ cord-022526-j9kg00qf 3384 2 changes change NNS cord-022526-j9kg00qf 3384 3 are be VBP cord-022526-j9kg00qf 3384 4 less less RBR cord-022526-j9kg00qf 3384 5 pronounced pronounced JJ cord-022526-j9kg00qf 3384 6 in in IN cord-022526-j9kg00qf 3384 7 the the DT cord-022526-j9kg00qf 3384 8 small small JJ cord-022526-j9kg00qf 3384 9 intestine intestine NN cord-022526-j9kg00qf 3384 10 than than IN cord-022526-j9kg00qf 3384 11 in in IN cord-022526-j9kg00qf 3384 12 the the DT cord-022526-j9kg00qf 3384 13 large large JJ cord-022526-j9kg00qf 3384 14 intestine intestine NN cord-022526-j9kg00qf 3384 15 , , , cord-022526-j9kg00qf 3385 1 9 9 CD cord-022526-j9kg00qf 3385 2 and and CC cord-022526-j9kg00qf 3385 3 small small JJ cord-022526-j9kg00qf 3385 4 intestinal intestinal JJ cord-022526-j9kg00qf 3385 5 lesions lesion NNS cord-022526-j9kg00qf 3385 6 predominate predominate VBP cord-022526-j9kg00qf 3385 7 segmentally segmentally RB cord-022526-j9kg00qf 3385 8 in in IN cord-022526-j9kg00qf 3385 9 the the DT cord-022526-j9kg00qf 3385 10 proximal proximal JJ cord-022526-j9kg00qf 3385 11 duodenum duodenum NN cord-022526-j9kg00qf 3385 12 and and CC cord-022526-j9kg00qf 3385 13 distal distal JJ cord-022526-j9kg00qf 3385 14 ileum ileum NN cord-022526-j9kg00qf 3385 15 . . . cord-022526-j9kg00qf 3386 1 Furthermore furthermore RB cord-022526-j9kg00qf 3386 2 , , , cord-022526-j9kg00qf 3386 3 significant significant JJ cord-022526-j9kg00qf 3386 4 hyperkeratosis hyperkeratosis NN cord-022526-j9kg00qf 3386 5 of of IN cord-022526-j9kg00qf 3386 6 the the DT cord-022526-j9kg00qf 3386 7 fundic fundic NNP cord-022526-j9kg00qf 3386 8 region region NN cord-022526-j9kg00qf 3386 9 may may MD cord-022526-j9kg00qf 3386 10 contribute contribute VB cord-022526-j9kg00qf 3386 11 to to IN cord-022526-j9kg00qf 3386 12 gastric gastric JJ cord-022526-j9kg00qf 3386 13 muscle muscle NN cord-022526-j9kg00qf 3386 14 contractile contractile JJ cord-022526-j9kg00qf 3386 15 disruption disruption NN cord-022526-j9kg00qf 3386 16 . . . cord-022526-j9kg00qf 3387 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3387 2 can can MD cord-022526-j9kg00qf 3387 3 be be VB cord-022526-j9kg00qf 3387 4 a a DT cord-022526-j9kg00qf 3387 5 consequence consequence NN cord-022526-j9kg00qf 3387 6 of of IN cord-022526-j9kg00qf 3387 7 the the DT cord-022526-j9kg00qf 3387 8 severe severe JJ cord-022526-j9kg00qf 3387 9 segmental segmental JJ cord-022526-j9kg00qf 3387 10 or or CC cord-022526-j9kg00qf 3387 11 multifocal multifocal JJ cord-022526-j9kg00qf 3387 12 granulomatous granulomatous JJ cord-022526-j9kg00qf 3387 13 lesions lesion NNS cord-022526-j9kg00qf 3387 14 in in IN cord-022526-j9kg00qf 3387 15 the the DT cord-022526-j9kg00qf 3387 16 large large JJ cord-022526-j9kg00qf 3387 17 intestine intestine NN cord-022526-j9kg00qf 3387 18 with with IN cord-022526-j9kg00qf 3387 19 mucosal mucosal NN cord-022526-j9kg00qf 3387 20 and and CC cord-022526-j9kg00qf 3387 21 transmural transmural JJ cord-022526-j9kg00qf 3387 22 thickening thickening NN cord-022526-j9kg00qf 3387 23 and and CC cord-022526-j9kg00qf 3387 24 extensive extensive JJ cord-022526-j9kg00qf 3387 25 ulceration ulceration NN cord-022526-j9kg00qf 3387 26 . . . cord-022526-j9kg00qf 3388 1 Abundant abundant JJ cord-022526-j9kg00qf 3388 2 fibrosis fibrosis NN cord-022526-j9kg00qf 3388 3 is be VBZ cord-022526-j9kg00qf 3388 4 a a DT cord-022526-j9kg00qf 3388 5 feature feature NN cord-022526-j9kg00qf 3388 6 of of IN cord-022526-j9kg00qf 3388 7 all all DT cord-022526-j9kg00qf 3388 8 affected affect VBN cord-022526-j9kg00qf 3388 9 tissues tissue NNS cord-022526-j9kg00qf 3388 10 ( ( -LRB- cord-022526-j9kg00qf 3388 11 see see VB cord-022526-j9kg00qf 3388 12 Table Table NNP cord-022526-j9kg00qf 3388 13 13 13 CD cord-022526-j9kg00qf 3388 14 .12 .12 CD cord-022526-j9kg00qf 3388 15 - - SYM cord-022526-j9kg00qf 3388 16 3 3 CD cord-022526-j9kg00qf 3388 17 ) ) -RRB- cord-022526-j9kg00qf 3388 18 . . . cord-022526-j9kg00qf 3389 1 The the DT cord-022526-j9kg00qf 3389 2 cause cause NN cord-022526-j9kg00qf 3389 3 of of IN cord-022526-j9kg00qf 3389 4 MEED MEED NNP cord-022526-j9kg00qf 3389 5 is be VBZ cord-022526-j9kg00qf 3389 6 unknown unknown JJ cord-022526-j9kg00qf 3389 7 and and CC cord-022526-j9kg00qf 3389 8 could could MD cord-022526-j9kg00qf 3389 9 represent represent VB cord-022526-j9kg00qf 3389 10 a a DT cord-022526-j9kg00qf 3389 11 chronic chronic JJ cord-022526-j9kg00qf 3389 12 ongoing ongoing JJ cord-022526-j9kg00qf 3389 13 immediate immediate JJ cord-022526-j9kg00qf 3389 14 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 3389 15 reaction reaction NN cord-022526-j9kg00qf 3389 16 against against IN cord-022526-j9kg00qf 3389 17 undefined undefined JJ cord-022526-j9kg00qf 3389 18 antigens antigen NNS cord-022526-j9kg00qf 3389 19 ingested ingest VBN cord-022526-j9kg00qf 3389 20 or or CC cord-022526-j9kg00qf 3389 21 excreted excrete VBN cord-022526-j9kg00qf 3389 22 into into IN cord-022526-j9kg00qf 3389 23 the the DT cord-022526-j9kg00qf 3389 24 affects affects NN cord-022526-j9kg00qf 3389 25 foals foal NNS cord-022526-j9kg00qf 3389 26 3 3 CD cord-022526-j9kg00qf 3389 27 to to TO cord-022526-j9kg00qf 3389 28 7 7 CD cord-022526-j9kg00qf 3389 29 months month NNS cord-022526-j9kg00qf 3389 30 of of IN cord-022526-j9kg00qf 3389 31 age age NN cord-022526-j9kg00qf 3389 32 , , , cord-022526-j9kg00qf 3389 33 particularly particularly RB cord-022526-j9kg00qf 3389 34 those those DT cord-022526-j9kg00qf 3389 35 that that WDT cord-022526-j9kg00qf 3389 36 have have VBP cord-022526-j9kg00qf 3389 37 been be VBN cord-022526-j9kg00qf 3389 38 weaned wean VBN cord-022526-j9kg00qf 3389 39 recently recently RB cord-022526-j9kg00qf 3389 40 . . . cord-022526-j9kg00qf 3390 1 The the DT cord-022526-j9kg00qf 3390 2 disease disease NN cord-022526-j9kg00qf 3390 3 is be VBZ cord-022526-j9kg00qf 3390 4 caused cause VBN cord-022526-j9kg00qf 3390 5 by by IN cord-022526-j9kg00qf 3390 6 Lawsonia Lawsonia NNP cord-022526-j9kg00qf 3390 7 intracellulare intracellulare NNP cord-022526-j9kg00qf 3390 8 , , , cord-022526-j9kg00qf 3390 9 an an DT cord-022526-j9kg00qf 3390 10 obligate obligate JJ cord-022526-j9kg00qf 3390 11 intracellular intracellular JJ cord-022526-j9kg00qf 3390 12 bacterium bacterium NN cord-022526-j9kg00qf 3390 13 found find VBN cord-022526-j9kg00qf 3390 14 in in IN cord-022526-j9kg00qf 3390 15 the the DT cord-022526-j9kg00qf 3390 16 cytoplasm cytoplasm NN cord-022526-j9kg00qf 3390 17 of of IN cord-022526-j9kg00qf 3390 18 proliferative proliferative JJ cord-022526-j9kg00qf 3390 19 crypt crypt JJ cord-022526-j9kg00qf 3390 20 epithelial epithelial JJ cord-022526-j9kg00qf 3390 21 cells cell NNS cord-022526-j9kg00qf 3390 22 of of IN cord-022526-j9kg00qf 3390 23 the the DT cord-022526-j9kg00qf 3390 24 intestine intestine NN cord-022526-j9kg00qf 3390 25 . . . cord-022526-j9kg00qf 3391 1 The the DT cord-022526-j9kg00qf 3391 2 condition condition NN cord-022526-j9kg00qf 3391 3 in in IN cord-022526-j9kg00qf 3391 4 a a DT cord-022526-j9kg00qf 3391 5 foal foal NN cord-022526-j9kg00qf 3391 6 was be VBD cord-022526-j9kg00qf 3391 7 described describe VBN cord-022526-j9kg00qf 3391 8 first first RB cord-022526-j9kg00qf 3391 9 as as IN cord-022526-j9kg00qf 3391 10 intestinal intestinal JJ cord-022526-j9kg00qf 3391 11 adenomatosis adenomatosis NN cord-022526-j9kg00qf 3391 12 , , , cord-022526-j9kg00qf 3391 13 24 24 CD cord-022526-j9kg00qf 3391 14 because because IN cord-022526-j9kg00qf 3391 15 of of IN cord-022526-j9kg00qf 3391 16 similarity similarity NN cord-022526-j9kg00qf 3391 17 to to IN cord-022526-j9kg00qf 3391 18 the the DT cord-022526-j9kg00qf 3391 19 swine swine NN cord-022526-j9kg00qf 3391 20 disorder disorder NN cord-022526-j9kg00qf 3391 21 of of IN cord-022526-j9kg00qf 3391 22 the the DT cord-022526-j9kg00qf 3391 23 same same JJ cord-022526-j9kg00qf 3391 24 name name NN cord-022526-j9kg00qf 3391 25 . . . cord-022526-j9kg00qf 3392 1 Later later RB cord-022526-j9kg00qf 3392 2 , , , cord-022526-j9kg00qf 3392 3 molecular molecular JJ cord-022526-j9kg00qf 3392 4 studies study NNS cord-022526-j9kg00qf 3392 5 showed show VBD cord-022526-j9kg00qf 3392 6 that that IN cord-022526-j9kg00qf 3392 7 intestines intestine NNS cord-022526-j9kg00qf 3392 8 from from IN cord-022526-j9kg00qf 3392 9 an an DT cord-022526-j9kg00qf 3392 10 affected affected JJ cord-022526-j9kg00qf 3392 11 foal foal NN cord-022526-j9kg00qf 3392 12 contained contain VBD cord-022526-j9kg00qf 3392 13 L. L. NNP cord-022526-j9kg00qf 3392 14 intracellulare intracellulare NNP cord-022526-j9kg00qf 3392 15 sequences sequence NNS cord-022526-j9kg00qf 3392 16 as as IN cord-022526-j9kg00qf 3392 17 determined determine VBN cord-022526-j9kg00qf 3392 18 by by IN cord-022526-j9kg00qf 3392 19 polymerase polymerase NN cord-022526-j9kg00qf 3392 20 chain chain NN cord-022526-j9kg00qf 3392 21 reaction reaction NN cord-022526-j9kg00qf 3392 22 analysis analysis NN cord-022526-j9kg00qf 3392 23 and and CC cord-022526-j9kg00qf 3392 24 confirmed confirm VBN cord-022526-j9kg00qf 3392 25 by by IN cord-022526-j9kg00qf 3392 26 Southern southern JJ cord-022526-j9kg00qf 3392 27 blot blot NN cord-022526-j9kg00qf 3392 28 hybridization hybridization NN cord-022526-j9kg00qf 3392 29 . . . cord-022526-j9kg00qf 3393 1 25 25 CD cord-022526-j9kg00qf 3394 1 Recently recently RB cord-022526-j9kg00qf 3394 2 , , , cord-022526-j9kg00qf 3394 3 studies study NNS cord-022526-j9kg00qf 3394 4 of of IN cord-022526-j9kg00qf 3394 5 a a DT cord-022526-j9kg00qf 3394 6 cluster cluster NN cord-022526-j9kg00qf 3394 7 of of IN cord-022526-j9kg00qf 3394 8 affected affected JJ cord-022526-j9kg00qf 3394 9 foals foal NNS cord-022526-j9kg00qf 3394 10 on on IN cord-022526-j9kg00qf 3394 11 three three CD cord-022526-j9kg00qf 3394 12 breeding breeding NN cord-022526-j9kg00qf 3394 13 farms farm NNS cord-022526-j9kg00qf 3394 14 in in IN cord-022526-j9kg00qf 3394 15 Canada Canada NNP cord-022526-j9kg00qf 3394 16 provided provide VBD cord-022526-j9kg00qf 3394 17 much much JJ cord-022526-j9kg00qf 3394 18 information information NN cord-022526-j9kg00qf 3394 19 on on IN cord-022526-j9kg00qf 3394 20 the the DT cord-022526-j9kg00qf 3394 21 clinical clinical JJ cord-022526-j9kg00qf 3394 22 syndrome syndrome NN cord-022526-j9kg00qf 3394 23 , , , cord-022526-j9kg00qf 3394 24 laboratory laboratory NN cord-022526-j9kg00qf 3394 25 investigations investigation NNS cord-022526-j9kg00qf 3394 26 , , , cord-022526-j9kg00qf 3394 27 and and CC cord-022526-j9kg00qf 3394 28 response response NN cord-022526-j9kg00qf 3394 29 to to IN cord-022526-j9kg00qf 3394 30 treatment treatment NN cord-022526-j9kg00qf 3394 31 . . . cord-022526-j9kg00qf 3395 1 2 2 LS cord-022526-j9kg00qf 3396 1 Two two CD cord-022526-j9kg00qf 3396 2 of of IN cord-022526-j9kg00qf 3396 3 the the DT cord-022526-j9kg00qf 3396 4 three three CD cord-022526-j9kg00qf 3396 5 farms farm NNS cord-022526-j9kg00qf 3396 6 bred breed VBD cord-022526-j9kg00qf 3396 7 Arabians Arabians NNPS cord-022526-j9kg00qf 3396 8 , , , cord-022526-j9kg00qf 3396 9 hence hence RB cord-022526-j9kg00qf 3396 10 a a DT cord-022526-j9kg00qf 3396 11 demographic demographic JJ cord-022526-j9kg00qf 3396 12 predominance predominance NN cord-022526-j9kg00qf 3396 13 of of IN cord-022526-j9kg00qf 3396 14 Arabian arabian JJ cord-022526-j9kg00qf 3396 15 foals foal NNS cord-022526-j9kg00qf 3396 16 exists exist VBZ cord-022526-j9kg00qf 3396 17 . . . cord-022526-j9kg00qf 3397 1 Clinical clinical JJ cord-022526-j9kg00qf 3397 2 signs sign NNS cord-022526-j9kg00qf 3397 3 included include VBD cord-022526-j9kg00qf 3397 4 depression depression NN cord-022526-j9kg00qf 3397 5 , , , cord-022526-j9kg00qf 3397 6 rapid rapid JJ cord-022526-j9kg00qf 3397 7 and and CC cord-022526-j9kg00qf 3397 8 significant significant JJ cord-022526-j9kg00qf 3397 9 weight weight NN cord-022526-j9kg00qf 3397 10 loss loss NN cord-022526-j9kg00qf 3397 11 , , , cord-022526-j9kg00qf 3397 12 edema edema NN cord-022526-j9kg00qf 3397 13 , , , cord-022526-j9kg00qf 3397 14 diarrhea diarrhea NN cord-022526-j9kg00qf 3397 15 , , , cord-022526-j9kg00qf 3397 16 and and CC cord-022526-j9kg00qf 3397 17 colic colic NN cord-022526-j9kg00qf 3397 18 . . . cord-022526-j9kg00qf 3398 1 Poor poor JJ cord-022526-j9kg00qf 3398 2 body body NN cord-022526-j9kg00qf 3398 3 condition condition NN cord-022526-j9kg00qf 3398 4 , , , cord-022526-j9kg00qf 3398 5 a a DT cord-022526-j9kg00qf 3398 6 rough rough JJ cord-022526-j9kg00qf 3398 7 hair hair NN cord-022526-j9kg00qf 3398 8 coat coat NN cord-022526-j9kg00qf 3398 9 , , , cord-022526-j9kg00qf 3398 10 and and CC cord-022526-j9kg00qf 3398 11 potbelly potbelly NN cord-022526-j9kg00qf 3398 12 appearance appearance NN cord-022526-j9kg00qf 3398 13 were be VBD cord-022526-j9kg00qf 3398 14 common common JJ cord-022526-j9kg00qf 3398 15 findings finding NNS cord-022526-j9kg00qf 3398 16 . . . cord-022526-j9kg00qf 3399 1 Other other JJ cord-022526-j9kg00qf 3399 2 problems problem NNS cord-022526-j9kg00qf 3399 3 often often RB cord-022526-j9kg00qf 3399 4 were be VBD cord-022526-j9kg00qf 3399 5 concurrent concurrent JJ cord-022526-j9kg00qf 3399 6 , , , cord-022526-j9kg00qf 3399 7 including include VBG cord-022526-j9kg00qf 3399 8 respiratory respiratory JJ cord-022526-j9kg00qf 3399 9 tract tract NN cord-022526-j9kg00qf 3399 10 infection infection NN cord-022526-j9kg00qf 3399 11 , , , cord-022526-j9kg00qf 3399 12 dermatitis dermatitis NN cord-022526-j9kg00qf 3399 13 , , , cord-022526-j9kg00qf 3399 14 intestinal intestinal JJ cord-022526-j9kg00qf 3399 15 parasitism parasitism NN cord-022526-j9kg00qf 3399 16 , , , cord-022526-j9kg00qf 3399 17 and and CC cord-022526-j9kg00qf 3399 18 gastric gastric JJ cord-022526-j9kg00qf 3399 19 ulceration ulceration NN cord-022526-j9kg00qf 3399 20 . . . cord-022526-j9kg00qf 3400 1 Significant significant JJ cord-022526-j9kg00qf 3400 2 laboratory laboratory NN cord-022526-j9kg00qf 3400 3 findings finding NNS cord-022526-j9kg00qf 3400 4 were be VBD cord-022526-j9kg00qf 3400 5 anemia anemia NN cord-022526-j9kg00qf 3400 6 , , , cord-022526-j9kg00qf 3400 7 transient transient JJ cord-022526-j9kg00qf 3400 8 leucocytosis leucocytosis NNP cord-022526-j9kg00qf 3400 9 , , , cord-022526-j9kg00qf 3400 10 hypoalbuminemia hypoalbuminemia NNP cord-022526-j9kg00qf 3400 11 , , , cord-022526-j9kg00qf 3400 12 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 3400 13 , , , cord-022526-j9kg00qf 3400 14 and and CC cord-022526-j9kg00qf 3400 15 elevated elevated JJ cord-022526-j9kg00qf 3400 16 serum serum NN cord-022526-j9kg00qf 3400 17 creatine creatine NN cord-022526-j9kg00qf 3400 18 kinase kinase NN cord-022526-j9kg00qf 3400 19 concentrations concentration NNS cord-022526-j9kg00qf 3400 20 . . . cord-022526-j9kg00qf 3401 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 3401 2 was be VBD cord-022526-j9kg00qf 3401 3 confirmed confirm VBN cord-022526-j9kg00qf 3401 4 by by IN cord-022526-j9kg00qf 3401 5 identifying identify VBG cord-022526-j9kg00qf 3401 6 characteristic characteristic JJ cord-022526-j9kg00qf 3401 7 intracellular intracellular JJ cord-022526-j9kg00qf 3401 8 bacteria bacteria NNS cord-022526-j9kg00qf 3401 9 within within IN cord-022526-j9kg00qf 3401 10 the the DT cord-022526-j9kg00qf 3401 11 apical apical JJ cord-022526-j9kg00qf 3401 12 cytoplasm cytoplasm NN cord-022526-j9kg00qf 3401 13 of of IN cord-022526-j9kg00qf 3401 14 proliferating proliferate VBG cord-022526-j9kg00qf 3401 15 crypt crypt JJ cord-022526-j9kg00qf 3401 16 epithelial epithelial JJ cord-022526-j9kg00qf 3401 17 cells cell NNS cord-022526-j9kg00qf 3401 18 using use VBG cord-022526-j9kg00qf 3401 19 silver silver NN cord-022526-j9kg00qf 3401 20 stains stain NNS cord-022526-j9kg00qf 3401 21 and and CC cord-022526-j9kg00qf 3401 22 by by IN cord-022526-j9kg00qf 3401 23 results result NNS cord-022526-j9kg00qf 3401 24 of of IN cord-022526-j9kg00qf 3401 25 polymerase polymerase NN cord-022526-j9kg00qf 3401 26 chain chain NN cord-022526-j9kg00qf 3401 27 reaction reaction NN cord-022526-j9kg00qf 3401 28 analysis analysis NN cord-022526-j9kg00qf 3401 29 and and CC cord-022526-j9kg00qf 3401 30 immunohistochemical immunohistochemical JJ cord-022526-j9kg00qf 3401 31 testing testing NN cord-022526-j9kg00qf 3401 32 . . . cord-022526-j9kg00qf 3402 1 Antemortem Antemortem NNP cord-022526-j9kg00qf 3402 2 diagnosis diagnosis NN cord-022526-j9kg00qf 3402 3 relied rely VBD cord-022526-j9kg00qf 3402 4 on on IN cord-022526-j9kg00qf 3402 5 clinical clinical JJ cord-022526-j9kg00qf 3402 6 signs sign NNS cord-022526-j9kg00qf 3402 7 , , , cord-022526-j9kg00qf 3402 8 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 3402 9 , , , cord-022526-j9kg00qf 3402 10 and and CC cord-022526-j9kg00qf 3402 11 exclusion exclusion NN cord-022526-j9kg00qf 3402 12 of of IN cord-022526-j9kg00qf 3402 13 common common JJ cord-022526-j9kg00qf 3402 14 enteric enteric JJ cord-022526-j9kg00qf 3402 15 infections infection NNS cord-022526-j9kg00qf 3402 16 . . . cord-022526-j9kg00qf 3403 1 One one PRP cord-022526-j9kg00qf 3403 2 can can MD cord-022526-j9kg00qf 3403 3 confirm confirm VB cord-022526-j9kg00qf 3403 4 diagnosis diagnosis NN cord-022526-j9kg00qf 3403 5 in in IN cord-022526-j9kg00qf 3403 6 live live JJ cord-022526-j9kg00qf 3403 7 animals animal NNS cord-022526-j9kg00qf 3403 8 by by IN cord-022526-j9kg00qf 3403 9 fecal fecal JJ cord-022526-j9kg00qf 3403 10 polymerase polymerase NN cord-022526-j9kg00qf 3403 11 chain chain NN cord-022526-j9kg00qf 3403 12 reaction reaction NN cord-022526-j9kg00qf 3403 13 analysis analysis NN cord-022526-j9kg00qf 3403 14 ( ( -LRB- cord-022526-j9kg00qf 3403 15 positive positive JJ cord-022526-j9kg00qf 3403 16 in in IN cord-022526-j9kg00qf 3403 17 6 6 CD cord-022526-j9kg00qf 3403 18 of of IN cord-022526-j9kg00qf 3403 19 18 18 CD cord-022526-j9kg00qf 3403 20 foals foal NNS cord-022526-j9kg00qf 3403 21 tested test VBN cord-022526-j9kg00qf 3403 22 ) ) -RRB- cord-022526-j9kg00qf 3403 23 and and CC cord-022526-j9kg00qf 3403 24 serologic serologic JJ cord-022526-j9kg00qf 3403 25 testing testing NN cord-022526-j9kg00qf 3403 26 ; ; : cord-022526-j9kg00qf 3403 27 7 7 CD cord-022526-j9kg00qf 3403 28 foals foal NNS cord-022526-j9kg00qf 3403 29 with with IN cord-022526-j9kg00qf 3403 30 proliferative proliferative JJ cord-022526-j9kg00qf 3403 31 enteropathy enteropathy NNS cord-022526-j9kg00qf 3403 32 were be VBD cord-022526-j9kg00qf 3403 33 evaluated evaluate VBN cord-022526-j9kg00qf 3403 34 serologically serologically RB cord-022526-j9kg00qf 3403 35 and and CC cord-022526-j9kg00qf 3403 36 had have VBD cord-022526-j9kg00qf 3403 37 antibodies antibody NNS cord-022526-j9kg00qf 3403 38 against against IN cord-022526-j9kg00qf 3403 39 Lawsonia Lawsonia NNP cord-022526-j9kg00qf 3403 40 intracellulare intracellulare NNP cord-022526-j9kg00qf 3403 41 . . . cord-022526-j9kg00qf 3404 1 2 2 LS cord-022526-j9kg00qf 3404 2 Treatment treatment NN cord-022526-j9kg00qf 3404 3 is be VBZ cord-022526-j9kg00qf 3404 4 effective effective JJ cord-022526-j9kg00qf 3404 5 . . . cord-022526-j9kg00qf 3405 1 Most Most JJS cord-022526-j9kg00qf 3405 2 foals foal NNS cord-022526-j9kg00qf 3405 3 received receive VBD cord-022526-j9kg00qf 3405 4 erythromycin erythromycin NNP cord-022526-j9kg00qf 3405 5 estolate estolate NNP cord-022526-j9kg00qf 3405 6 ( ( -LRB- cord-022526-j9kg00qf 3405 7 15 15 CD cord-022526-j9kg00qf 3405 8 to to TO cord-022526-j9kg00qf 3405 9 25 25 CD cord-022526-j9kg00qf 3405 10 mg mg NNP cord-022526-j9kg00qf 3405 11 / / SYM cord-022526-j9kg00qf 3405 12 kg kg NN cord-022526-j9kg00qf 3405 13 per per IN cord-022526-j9kg00qf 3405 14 os os NN cord-022526-j9kg00qf 3405 15 every every DT cord-022526-j9kg00qf 3405 16 6 6 CD cord-022526-j9kg00qf 3405 17 to to TO cord-022526-j9kg00qf 3405 18 8 8 CD cord-022526-j9kg00qf 3405 19 hours hour NNS cord-022526-j9kg00qf 3405 20 ) ) -RRB- cord-022526-j9kg00qf 3405 21 , , , cord-022526-j9kg00qf 3405 22 alone alone RB cord-022526-j9kg00qf 3405 23 or or CC cord-022526-j9kg00qf 3405 24 with with IN cord-022526-j9kg00qf 3405 25 rifampin rifampin NNP cord-022526-j9kg00qf 3405 26 ( ( -LRB- cord-022526-j9kg00qf 3405 27 7 7 CD cord-022526-j9kg00qf 3405 28 to to TO cord-022526-j9kg00qf 3405 29 10 10 CD cord-022526-j9kg00qf 3405 30 mg mg NN cord-022526-j9kg00qf 3405 31 / / SYM cord-022526-j9kg00qf 3405 32 kg kg NN cord-022526-j9kg00qf 3405 33 per per IN cord-022526-j9kg00qf 3405 34 os os NN cord-022526-j9kg00qf 3405 35 every every DT cord-022526-j9kg00qf 3405 36 12 12 CD cord-022526-j9kg00qf 3405 37 hours hour NNS cord-022526-j9kg00qf 3405 38 ) ) -RRB- cord-022526-j9kg00qf 3405 39 for for IN cord-022526-j9kg00qf 3405 40 2 2 CD cord-022526-j9kg00qf 3405 41 to to TO cord-022526-j9kg00qf 3405 42 4 4 CD cord-022526-j9kg00qf 3405 43 weeks week NNS cord-022526-j9kg00qf 3405 44 . . . cord-022526-j9kg00qf 3406 1 Foals foal NNS cord-022526-j9kg00qf 3406 2 frequently frequently RB cord-022526-j9kg00qf 3406 3 needed need VBD cord-022526-j9kg00qf 3406 4 supportive supportive JJ cord-022526-j9kg00qf 3406 5 therapy therapy NN cord-022526-j9kg00qf 3406 6 at at IN cord-022526-j9kg00qf 3406 7 the the DT cord-022526-j9kg00qf 3406 8 outset outset NN cord-022526-j9kg00qf 3406 9 for for IN cord-022526-j9kg00qf 3406 10 stabilization stabilization NN cord-022526-j9kg00qf 3406 11 . . . cord-022526-j9kg00qf 3407 1 Response response NN cord-022526-j9kg00qf 3407 2 to to IN cord-022526-j9kg00qf 3407 3 therapy therapy NN cord-022526-j9kg00qf 3407 4 has have VBZ cord-022526-j9kg00qf 3407 5 been be VBN cord-022526-j9kg00qf 3407 6 excellent excellent JJ cord-022526-j9kg00qf 3407 7 . . . cord-022526-j9kg00qf 3408 1 2 2 LS cord-022526-j9kg00qf 3409 1 Rapid rapid JJ cord-022526-j9kg00qf 3409 2 improvement improvement NN cord-022526-j9kg00qf 3409 3 in in IN cord-022526-j9kg00qf 3409 4 clinical clinical JJ cord-022526-j9kg00qf 3409 5 signs sign NNS cord-022526-j9kg00qf 3409 6 even even RB cord-022526-j9kg00qf 3409 7 within within IN cord-022526-j9kg00qf 3409 8 24 24 CD cord-022526-j9kg00qf 3409 9 hours hour NNS cord-022526-j9kg00qf 3409 10 preceded precede VBD cord-022526-j9kg00qf 3409 11 the the DT cord-022526-j9kg00qf 3409 12 rise rise NN cord-022526-j9kg00qf 3409 13 in in IN cord-022526-j9kg00qf 3409 14 plasma plasma NN cord-022526-j9kg00qf 3409 15 protein protein NN cord-022526-j9kg00qf 3409 16 concentration concentration NN cord-022526-j9kg00qf 3409 17 . . . cord-022526-j9kg00qf 3410 1 The the DT cord-022526-j9kg00qf 3410 2 source source NN cord-022526-j9kg00qf 3410 3 of of IN cord-022526-j9kg00qf 3410 4 the the DT cord-022526-j9kg00qf 3410 5 infection infection NN cord-022526-j9kg00qf 3410 6 was be VBD cord-022526-j9kg00qf 3410 7 undetermined undetermined JJ cord-022526-j9kg00qf 3410 8 . . . cord-022526-j9kg00qf 3411 1 No no DT cord-022526-j9kg00qf 3411 2 apparent apparent JJ cord-022526-j9kg00qf 3411 3 link link NN cord-022526-j9kg00qf 3411 4 existed exist VBD cord-022526-j9kg00qf 3411 5 between between IN cord-022526-j9kg00qf 3411 6 the the DT cord-022526-j9kg00qf 3411 7 three three CD cord-022526-j9kg00qf 3411 8 farms farm NNS cord-022526-j9kg00qf 3411 9 and and CC cord-022526-j9kg00qf 3411 10 a a DT cord-022526-j9kg00qf 3411 11 swine swine NN cord-022526-j9kg00qf 3411 12 operation operation NN cord-022526-j9kg00qf 3411 13 or or CC cord-022526-j9kg00qf 3411 14 solid solid JJ cord-022526-j9kg00qf 3411 15 and and CC cord-022526-j9kg00qf 3411 16 liquid liquid JJ cord-022526-j9kg00qf 3411 17 waste waste NN cord-022526-j9kg00qf 3411 18 disposal disposal NN cord-022526-j9kg00qf 3411 19 on on IN cord-022526-j9kg00qf 3411 20 pasture pasture NN cord-022526-j9kg00qf 3411 21 . . . cord-022526-j9kg00qf 3412 1 However however RB cord-022526-j9kg00qf 3412 2 , , , cord-022526-j9kg00qf 3412 3 one one PRP cord-022526-j9kg00qf 3412 4 can can MD cord-022526-j9kg00qf 3412 5 not not RB cord-022526-j9kg00qf 3412 6 exclude exclude VB cord-022526-j9kg00qf 3412 7 airborne airborne JJ cord-022526-j9kg00qf 3412 8 spread spread NN cord-022526-j9kg00qf 3412 9 of of IN cord-022526-j9kg00qf 3412 10 dried dry VBN cord-022526-j9kg00qf 3412 11 fecal fecal JJ cord-022526-j9kg00qf 3412 12 material material NN cord-022526-j9kg00qf 3412 13 over over IN cord-022526-j9kg00qf 3412 14 distances distance NNS cord-022526-j9kg00qf 3412 15 . . . cord-022526-j9kg00qf 3413 1 Comparisons comparison NNS cord-022526-j9kg00qf 3413 2 of of IN cord-022526-j9kg00qf 3413 3 epidemiologic epidemiologic JJ cord-022526-j9kg00qf 3413 4 findings finding NNS cord-022526-j9kg00qf 3413 5 from from IN cord-022526-j9kg00qf 3413 6 the the DT cord-022526-j9kg00qf 3413 7 swine swine NN cord-022526-j9kg00qf 3413 8 disease disease NN cord-022526-j9kg00qf 3413 9 indicated indicate VBD cord-022526-j9kg00qf 3413 10 that that IN cord-022526-j9kg00qf 3413 11 overcrowding overcrowding NN cord-022526-j9kg00qf 3413 12 , , , cord-022526-j9kg00qf 3413 13 feed feed NN cord-022526-j9kg00qf 3413 14 changes change NNS cord-022526-j9kg00qf 3413 15 , , , cord-022526-j9kg00qf 3413 16 antibiotic antibiotic JJ cord-022526-j9kg00qf 3413 17 usage usage NN cord-022526-j9kg00qf 3413 18 , , , cord-022526-j9kg00qf 3413 19 and and CC cord-022526-j9kg00qf 3413 20 mixing mixing NN cord-022526-j9kg00qf 3413 21 and and CC cord-022526-j9kg00qf 3413 22 transportation transportation NN cord-022526-j9kg00qf 3413 23 were be VBD cord-022526-j9kg00qf 3413 24 potential potential JJ cord-022526-j9kg00qf 3413 25 risk risk NN cord-022526-j9kg00qf 3413 26 factors factor NNS cord-022526-j9kg00qf 3413 27 at at IN cord-022526-j9kg00qf 3413 28 two two CD cord-022526-j9kg00qf 3413 29 of of IN cord-022526-j9kg00qf 3413 30 the the DT cord-022526-j9kg00qf 3413 31 farms farm NNS cord-022526-j9kg00qf 3413 32 . . . cord-022526-j9kg00qf 3414 1 Recent recent JJ cord-022526-j9kg00qf 3414 2 weaning weaning NN cord-022526-j9kg00qf 3414 3 appeared appear VBD cord-022526-j9kg00qf 3414 4 to to TO cord-022526-j9kg00qf 3414 5 be be VB cord-022526-j9kg00qf 3414 6 a a DT cord-022526-j9kg00qf 3414 7 key key JJ cord-022526-j9kg00qf 3414 8 element element NN cord-022526-j9kg00qf 3414 9 in in IN cord-022526-j9kg00qf 3414 10 the the DT cord-022526-j9kg00qf 3414 11 pathogenesis pathogenesis NN cord-022526-j9kg00qf 3414 12 . . . cord-022526-j9kg00qf 3415 1 24 24 CD cord-022526-j9kg00qf 3415 2 _SP cord-022526-j9kg00qf 3416 1 Samuel Samuel NNP cord-022526-j9kg00qf 3416 2 L. L. NNP cord-022526-j9kg00qf 3416 3 Jones Jones NNP cord-022526-j9kg00qf 3416 4 Acute Acute NNP cord-022526-j9kg00qf 3416 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3416 6 caused cause VBN cord-022526-j9kg00qf 3416 7 by by IN cord-022526-j9kg00qf 3416 8 colitis colitis NN cord-022526-j9kg00qf 3416 9 in in IN cord-022526-j9kg00qf 3416 10 adult adult NN cord-022526-j9kg00qf 3416 11 or or CC cord-022526-j9kg00qf 3416 12 young young JJ cord-022526-j9kg00qf 3416 13 horses horse NNS cord-022526-j9kg00qf 3416 14 is be VBZ cord-022526-j9kg00qf 3416 15 a a DT cord-022526-j9kg00qf 3416 16 potentially potentially RB cord-022526-j9kg00qf 3416 17 life life NN cord-022526-j9kg00qf 3416 18 - - HYPH cord-022526-j9kg00qf 3416 19 threatening threaten VBG cord-022526-j9kg00qf 3416 20 disorder disorder NN cord-022526-j9kg00qf 3416 21 of of IN cord-022526-j9kg00qf 3416 22 a a DT cord-022526-j9kg00qf 3416 23 variety variety NN cord-022526-j9kg00qf 3416 24 of of IN cord-022526-j9kg00qf 3416 25 causes cause NNS cord-022526-j9kg00qf 3416 26 ( ( -LRB- cord-022526-j9kg00qf 3416 27 Table table NN cord-022526-j9kg00qf 3416 28 13 13 CD cord-022526-j9kg00qf 3416 29 .13 .13 CD cord-022526-j9kg00qf 3416 30 - - SYM cord-022526-j9kg00qf 3416 31 1 1 CD cord-022526-j9kg00qf 3416 32 ) ) -RRB- cord-022526-j9kg00qf 3416 33 characterized characterize VBN cord-022526-j9kg00qf 3416 34 by by IN cord-022526-j9kg00qf 3416 35 hypersecretion hypersecretion NN cord-022526-j9kg00qf 3416 36 of of IN cord-022526-j9kg00qf 3416 37 fluid fluid NN cord-022526-j9kg00qf 3416 38 , , , cord-022526-j9kg00qf 3416 39 motility motility NN cord-022526-j9kg00qf 3416 40 disturbances disturbance NNS cord-022526-j9kg00qf 3416 41 , , , cord-022526-j9kg00qf 3416 42 altered alter VBN cord-022526-j9kg00qf 3416 43 microbial microbial JJ cord-022526-j9kg00qf 3416 44 flora flora NNS cord-022526-j9kg00qf 3416 45 in in IN cord-022526-j9kg00qf 3416 46 the the DT cord-022526-j9kg00qf 3416 47 colon colon NN cord-022526-j9kg00qf 3416 48 , , , cord-022526-j9kg00qf 3416 49 and and CC cord-022526-j9kg00qf 3416 50 an an DT cord-022526-j9kg00qf 3416 51 impaired impaired JJ cord-022526-j9kg00qf 3416 52 mucosal mucosal JJ cord-022526-j9kg00qf 3416 53 barrier barrier NN cord-022526-j9kg00qf 3416 54 caused cause VBN cord-022526-j9kg00qf 3416 55 by by IN cord-022526-j9kg00qf 3416 56 direct direct JJ cord-022526-j9kg00qf 3416 57 injury injury NN cord-022526-j9kg00qf 3416 58 or or CC cord-022526-j9kg00qf 3416 59 inflammation inflammation NN cord-022526-j9kg00qf 3416 60 . . . cord-022526-j9kg00qf 3417 1 Many many JJ cord-022526-j9kg00qf 3417 2 of of IN cord-022526-j9kg00qf 3417 3 the the DT cord-022526-j9kg00qf 3417 4 clinical clinical JJ cord-022526-j9kg00qf 3417 5 and and CC cord-022526-j9kg00qf 3417 6 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 3417 7 features feature NNS cord-022526-j9kg00qf 3417 8 are be VBP cord-022526-j9kg00qf 3417 9 similar similar JJ cord-022526-j9kg00qf 3417 10 regardless regardless RB cord-022526-j9kg00qf 3417 11 of of IN cord-022526-j9kg00qf 3417 12 the the DT cord-022526-j9kg00qf 3417 13 cause cause NN cord-022526-j9kg00qf 3417 14 . . . cord-022526-j9kg00qf 3418 1 Severe severe JJ cord-022526-j9kg00qf 3418 2 dehydration dehydration NN cord-022526-j9kg00qf 3418 3 with with IN cord-022526-j9kg00qf 3418 4 profound profound JJ cord-022526-j9kg00qf 3418 5 electrolyte electrolyte JJ cord-022526-j9kg00qf 3418 6 abnormalities abnormality NNS cord-022526-j9kg00qf 3418 7 is be VBZ cord-022526-j9kg00qf 3418 8 common common JJ cord-022526-j9kg00qf 3418 9 , , , cord-022526-j9kg00qf 3418 10 as as IN cord-022526-j9kg00qf 3418 11 is be VBZ cord-022526-j9kg00qf 3418 12 systemic systemic JJ cord-022526-j9kg00qf 3418 13 inflammation inflammation NN cord-022526-j9kg00qf 3418 14 from from IN cord-022526-j9kg00qf 3418 15 absorption absorption NN cord-022526-j9kg00qf 3418 16 of of IN cord-022526-j9kg00qf 3418 17 endotoxin endotoxin NN cord-022526-j9kg00qf 3418 18 or or CC cord-022526-j9kg00qf 3418 19 other other JJ cord-022526-j9kg00qf 3418 20 bacterial bacterial JJ cord-022526-j9kg00qf 3418 21 products product NNS cord-022526-j9kg00qf 3418 22 through through IN cord-022526-j9kg00qf 3418 23 the the DT cord-022526-j9kg00qf 3418 24 compromised compromise VBN cord-022526-j9kg00qf 3418 25 mucosa mucosa NN cord-022526-j9kg00qf 3418 26 . . . cord-022526-j9kg00qf 3419 1 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3419 2 protein protein NN cord-022526-j9kg00qf 3419 3 loss loss NN cord-022526-j9kg00qf 3419 4 may may MD cord-022526-j9kg00qf 3419 5 result result VB cord-022526-j9kg00qf 3419 6 in in IN cord-022526-j9kg00qf 3419 7 reduced reduce VBN cord-022526-j9kg00qf 3419 8 colloid colloid NN cord-022526-j9kg00qf 3419 9 oncotic oncotic JJ cord-022526-j9kg00qf 3419 10 pressure pressure NN cord-022526-j9kg00qf 3419 11 from from IN cord-022526-j9kg00qf 3419 12 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 3419 13 , , , cord-022526-j9kg00qf 3419 14 leading lead VBG cord-022526-j9kg00qf 3419 15 to to IN cord-022526-j9kg00qf 3419 16 tissue tissue NN cord-022526-j9kg00qf 3419 17 edema edema NN cord-022526-j9kg00qf 3419 18 . . . cord-022526-j9kg00qf 3420 1 Colitis colitis NN cord-022526-j9kg00qf 3420 2 is be VBZ cord-022526-j9kg00qf 3420 3 a a DT cord-022526-j9kg00qf 3420 4 highly highly RB cord-022526-j9kg00qf 3420 5 catabolic catabolic JJ cord-022526-j9kg00qf 3420 6 disorder disorder NN cord-022526-j9kg00qf 3420 7 , , , cord-022526-j9kg00qf 3420 8 and and CC cord-022526-j9kg00qf 3420 9 weight weight NN cord-022526-j9kg00qf 3420 10 loss loss NN cord-022526-j9kg00qf 3420 11 may may MD cord-022526-j9kg00qf 3420 12 be be VB cord-022526-j9kg00qf 3420 13 rapid rapid JJ cord-022526-j9kg00qf 3420 14 and and CC cord-022526-j9kg00qf 3420 15 severe severe JJ cord-022526-j9kg00qf 3420 16 . . . cord-022526-j9kg00qf 3421 1 Some some DT cord-022526-j9kg00qf 3421 2 cases case NNS cord-022526-j9kg00qf 3421 3 of of IN cord-022526-j9kg00qf 3421 4 colitis colitis NN cord-022526-j9kg00qf 3421 5 may may MD cord-022526-j9kg00qf 3421 6 be be VB cord-022526-j9kg00qf 3421 7 complicated complicate VBN cord-022526-j9kg00qf 3421 8 by by IN cord-022526-j9kg00qf 3421 9 extensive extensive JJ cord-022526-j9kg00qf 3421 10 mucosal mucosal JJ cord-022526-j9kg00qf 3421 11 ulceration ulceration NN cord-022526-j9kg00qf 3421 12 , , , cord-022526-j9kg00qf 3421 13 serosal serosal NN cord-022526-j9kg00qf 3421 14 inflammation inflammation NN cord-022526-j9kg00qf 3421 15 , , , cord-022526-j9kg00qf 3421 16 or or CC cord-022526-j9kg00qf 3421 17 mural mural NN cord-022526-j9kg00qf 3421 18 ischemia ischemia NN cord-022526-j9kg00qf 3421 19 / / SYM cord-022526-j9kg00qf 3421 20 infarction infarction NN cord-022526-j9kg00qf 3421 21 extending extend VBG cord-022526-j9kg00qf 3421 22 from from IN cord-022526-j9kg00qf 3421 23 the the DT cord-022526-j9kg00qf 3421 24 inflammation inflammation NN cord-022526-j9kg00qf 3421 25 or or CC cord-022526-j9kg00qf 3421 26 resulting result VBG cord-022526-j9kg00qf 3421 27 from from IN cord-022526-j9kg00qf 3421 28 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 3421 29 . . . cord-022526-j9kg00qf 3422 1 Thus thus RB cord-022526-j9kg00qf 3422 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 3422 3 measures measure NNS cord-022526-j9kg00qf 3422 4 aimed aim VBN cord-022526-j9kg00qf 3422 5 at at IN cord-022526-j9kg00qf 3422 6 determining determine VBG cord-022526-j9kg00qf 3422 7 the the DT cord-022526-j9kg00qf 3422 8 cause cause NN cord-022526-j9kg00qf 3422 9 necessarily necessarily RB cord-022526-j9kg00qf 3422 10 must must MD cord-022526-j9kg00qf 3422 11 be be VB cord-022526-j9kg00qf 3422 12 accompanied accompany VBN cord-022526-j9kg00qf 3422 13 by by IN cord-022526-j9kg00qf 3422 14 clinical clinical JJ cord-022526-j9kg00qf 3422 15 and and CC cord-022526-j9kg00qf 3422 16 laboratory laboratory NN cord-022526-j9kg00qf 3422 17 assessment assessment NN cord-022526-j9kg00qf 3422 18 of of IN cord-022526-j9kg00qf 3422 19 hydration hydration NN cord-022526-j9kg00qf 3422 20 , , , cord-022526-j9kg00qf 3422 21 electrolyte electrolyte NN cord-022526-j9kg00qf 3422 22 and and CC cord-022526-j9kg00qf 3422 23 acid acid NN cord-022526-j9kg00qf 3422 24 - - HYPH cord-022526-j9kg00qf 3422 25 base base NN cord-022526-j9kg00qf 3422 26 balance balance NN cord-022526-j9kg00qf 3422 27 , , , cord-022526-j9kg00qf 3422 28 plasma plasma NN cord-022526-j9kg00qf 3422 29 protein protein NN cord-022526-j9kg00qf 3422 30 concentration concentration NN cord-022526-j9kg00qf 3422 31 and and CC cord-022526-j9kg00qf 3422 32 colloid colloid NN cord-022526-j9kg00qf 3422 33 oncotic oncotic JJ cord-022526-j9kg00qf 3422 34 pressure pressure NN cord-022526-j9kg00qf 3422 35 , , , cord-022526-j9kg00qf 3422 36 organ organ NN cord-022526-j9kg00qf 3422 37 function function NN cord-022526-j9kg00qf 3422 38 , , , cord-022526-j9kg00qf 3422 39 and and CC cord-022526-j9kg00qf 3422 40 evaluation evaluation NN cord-022526-j9kg00qf 3422 41 of of IN cord-022526-j9kg00qf 3422 42 the the DT cord-022526-j9kg00qf 3422 43 degree degree NN cord-022526-j9kg00qf 3422 44 of of IN cord-022526-j9kg00qf 3422 45 systemic systemic JJ cord-022526-j9kg00qf 3422 46 inflammation inflammation NN cord-022526-j9kg00qf 3422 47 and and CC cord-022526-j9kg00qf 3422 48 of of IN cord-022526-j9kg00qf 3422 49 the the DT cord-022526-j9kg00qf 3422 50 integrity integrity NN cord-022526-j9kg00qf 3422 51 of of IN cord-022526-j9kg00qf 3422 52 the the DT cord-022526-j9kg00qf 3422 53 intestinal intestinal JJ cord-022526-j9kg00qf 3422 54 wall wall NN cord-022526-j9kg00qf 3422 55 . . . cord-022526-j9kg00qf 3423 1 Although although IN cord-022526-j9kg00qf 3423 2 therapeutic therapeutic JJ cord-022526-j9kg00qf 3423 3 strategies strategy NNS cord-022526-j9kg00qf 3423 4 are be VBP cord-022526-j9kg00qf 3423 5 similar similar JJ cord-022526-j9kg00qf 3423 6 for for IN cord-022526-j9kg00qf 3423 7 many many JJ cord-022526-j9kg00qf 3423 8 causes cause NNS cord-022526-j9kg00qf 3423 9 of of IN cord-022526-j9kg00qf 3423 10 colitis colitis NN cord-022526-j9kg00qf 3423 11 , , , cord-022526-j9kg00qf 3423 12 consisting consist VBG cord-022526-j9kg00qf 3423 13 primarily primarily RB cord-022526-j9kg00qf 3423 14 of of IN cord-022526-j9kg00qf 3423 15 control control NN cord-022526-j9kg00qf 3423 16 of of IN cord-022526-j9kg00qf 3423 17 local local JJ cord-022526-j9kg00qf 3423 18 and and CC cord-022526-j9kg00qf 3423 19 systemic systemic JJ cord-022526-j9kg00qf 3423 20 inflammation inflammation NN cord-022526-j9kg00qf 3423 21 , , , cord-022526-j9kg00qf 3423 22 maintenance maintenance NN cord-022526-j9kg00qf 3423 23 of of IN cord-022526-j9kg00qf 3423 24 fluid fluid NN cord-022526-j9kg00qf 3423 25 and and CC cord-022526-j9kg00qf 3423 26 electrolyte electrolyte JJ cord-022526-j9kg00qf 3423 27 balance balance NN cord-022526-j9kg00qf 3423 28 , , , cord-022526-j9kg00qf 3423 29 promotion promotion NN cord-022526-j9kg00qf 3423 30 of of IN cord-022526-j9kg00qf 3423 31 tissue tissue NN cord-022526-j9kg00qf 3423 32 perfusion perfusion NN cord-022526-j9kg00qf 3423 33 , , , cord-022526-j9kg00qf 3423 34 replacement replacement NN cord-022526-j9kg00qf 3423 35 of of IN cord-022526-j9kg00qf 3423 36 plasma plasma NN cord-022526-j9kg00qf 3423 37 protein protein NN cord-022526-j9kg00qf 3423 38 , , , cord-022526-j9kg00qf 3423 39 preservation preservation NN cord-022526-j9kg00qf 3423 40 of of IN cord-022526-j9kg00qf 3423 41 colloid colloid NN cord-022526-j9kg00qf 3423 42 oncotic oncotic JJ cord-022526-j9kg00qf 3423 43 pressure pressure NN cord-022526-j9kg00qf 3423 44 , , , cord-022526-j9kg00qf 3423 45 promotion promotion NN cord-022526-j9kg00qf 3423 46 of of IN cord-022526-j9kg00qf 3423 47 mucosal mucosal JJ cord-022526-j9kg00qf 3423 48 repair repair NN cord-022526-j9kg00qf 3423 49 , , , cord-022526-j9kg00qf 3423 50 restoration restoration NN cord-022526-j9kg00qf 3423 51 of of IN cord-022526-j9kg00qf 3423 52 the the DT cord-022526-j9kg00qf 3423 53 microbial microbial JJ cord-022526-j9kg00qf 3423 54 ecology ecology NN cord-022526-j9kg00qf 3423 55 of of IN cord-022526-j9kg00qf 3423 56 the the DT cord-022526-j9kg00qf 3423 57 colon colon NN cord-022526-j9kg00qf 3423 58 , , , cord-022526-j9kg00qf 3423 59 and and CC cord-022526-j9kg00qf 3423 60 nutritional nutritional JJ cord-022526-j9kg00qf 3423 61 management management NN cord-022526-j9kg00qf 3423 62 , , , cord-022526-j9kg00qf 3423 63 some some DT cord-022526-j9kg00qf 3423 64 causes cause NNS cord-022526-j9kg00qf 3423 65 of of IN cord-022526-j9kg00qf 3423 66 acute acute JJ cord-022526-j9kg00qf 3423 67 colitis colitis NN cord-022526-j9kg00qf 3423 68 have have VBP cord-022526-j9kg00qf 3423 69 specific specific JJ cord-022526-j9kg00qf 3423 70 therapies therapy NNS cord-022526-j9kg00qf 3423 71 aimed aim VBN cord-022526-j9kg00qf 3423 72 at at IN cord-022526-j9kg00qf 3423 73 eliminating eliminate VBG cord-022526-j9kg00qf 3423 74 the the DT cord-022526-j9kg00qf 3423 75 cause cause NN cord-022526-j9kg00qf 3423 76 . . . cord-022526-j9kg00qf 3424 1 A a DT cord-022526-j9kg00qf 3424 2 variety variety NN cord-022526-j9kg00qf 3424 3 of of IN cord-022526-j9kg00qf 3424 4 infectious infectious JJ cord-022526-j9kg00qf 3424 5 organisms organism NNS cord-022526-j9kg00qf 3424 6 has have VBZ cord-022526-j9kg00qf 3424 7 been be VBN cord-022526-j9kg00qf 3424 8 identified identify VBN cord-022526-j9kg00qf 3424 9 as as IN cord-022526-j9kg00qf 3424 10 causes cause NNS cord-022526-j9kg00qf 3424 11 of of IN cord-022526-j9kg00qf 3424 12 acute acute JJ cord-022526-j9kg00qf 3424 13 colitis colitis NN cord-022526-j9kg00qf 3424 14 in in IN cord-022526-j9kg00qf 3424 15 adult adult NN cord-022526-j9kg00qf 3424 16 horses horse NNS cord-022526-j9kg00qf 3424 17 . . . cord-022526-j9kg00qf 3425 1 The the DT cord-022526-j9kg00qf 3425 2 clinical clinical JJ cord-022526-j9kg00qf 3425 3 syndromes syndrome NNS cord-022526-j9kg00qf 3425 4 associated associate VBN cord-022526-j9kg00qf 3425 5 with with IN cord-022526-j9kg00qf 3425 6 these these DT cord-022526-j9kg00qf 3425 7 infections infection NNS cord-022526-j9kg00qf 3425 8 are be VBP cord-022526-j9kg00qf 3425 9 indistinguishable indistinguishable JJ cord-022526-j9kg00qf 3425 10 in in IN cord-022526-j9kg00qf 3425 11 most most JJS cord-022526-j9kg00qf 3425 12 horses horse NNS cord-022526-j9kg00qf 3425 13 . . . cord-022526-j9kg00qf 3426 1 However however RB cord-022526-j9kg00qf 3426 2 , , , cord-022526-j9kg00qf 3426 3 appropriate appropriate JJ cord-022526-j9kg00qf 3426 4 diagnostic diagnostic JJ cord-022526-j9kg00qf 3426 5 tests test NNS cord-022526-j9kg00qf 3426 6 including include VBG cord-022526-j9kg00qf 3426 7 fecal fecal JJ cord-022526-j9kg00qf 3426 8 bacterial bacterial JJ cord-022526-j9kg00qf 3426 9 culture culture NN cord-022526-j9kg00qf 3426 10 , , , cord-022526-j9kg00qf 3426 11 fecal fecal JJ cord-022526-j9kg00qf 3426 12 bacterial bacterial JJ cord-022526-j9kg00qf 3426 13 toxin toxin NN cord-022526-j9kg00qf 3426 14 analysis analysis NN cord-022526-j9kg00qf 3426 15 , , , cord-022526-j9kg00qf 3426 16 PCR PCR NNP cord-022526-j9kg00qf 3426 17 , , , cord-022526-j9kg00qf 3426 18 and/or and/or CC cord-022526-j9kg00qf 3426 19 serology serology NN cord-022526-j9kg00qf 3426 20 may may MD cord-022526-j9kg00qf 3426 21 identify identify VB cord-022526-j9kg00qf 3426 22 specific specific JJ cord-022526-j9kg00qf 3426 23 infectious infectious JJ cord-022526-j9kg00qf 3426 24 organisms organism NNS cord-022526-j9kg00qf 3426 25 . . . cord-022526-j9kg00qf 3427 1 Salmonella salmonella NN cord-022526-j9kg00qf 3427 2 is be VBZ cord-022526-j9kg00qf 3427 3 a a DT cord-022526-j9kg00qf 3427 4 genus genus NN cord-022526-j9kg00qf 3427 5 of of IN cord-022526-j9kg00qf 3427 6 gram gram NN cord-022526-j9kg00qf 3427 7 - - HYPH cord-022526-j9kg00qf 3427 8 negative negative JJ cord-022526-j9kg00qf 3427 9 facultatively facultatively RB cord-022526-j9kg00qf 3427 10 anaerobic anaerobic JJ cord-022526-j9kg00qf 3427 11 bacteria bacteria NNS cord-022526-j9kg00qf 3427 12 that that WDT cord-022526-j9kg00qf 3427 13 are be VBP cord-022526-j9kg00qf 3427 14 common common JJ cord-022526-j9kg00qf 3427 15 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3427 16 pathogens pathogen NNS cord-022526-j9kg00qf 3427 17 in in IN cord-022526-j9kg00qf 3427 18 horses horse NNS cord-022526-j9kg00qf 3427 19 . . . cord-022526-j9kg00qf 3428 1 Many many JJ cord-022526-j9kg00qf 3428 2 serotypes serotype NNS cord-022526-j9kg00qf 3428 3 of of IN cord-022526-j9kg00qf 3428 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 3428 5 have have VBP cord-022526-j9kg00qf 3428 6 been be VBN cord-022526-j9kg00qf 3428 7 reported report VBN cord-022526-j9kg00qf 3428 8 to to TO cord-022526-j9kg00qf 3428 9 infect infect VB cord-022526-j9kg00qf 3428 10 horses horse NNS cord-022526-j9kg00qf 3428 11 , , , cord-022526-j9kg00qf 3428 12 but but CC cord-022526-j9kg00qf 3428 13 those those DT cord-022526-j9kg00qf 3428 14 classified classify VBN cord-022526-j9kg00qf 3428 15 in in IN cord-022526-j9kg00qf 3428 16 group group NN cord-022526-j9kg00qf 3428 17 B B NNP cord-022526-j9kg00qf 3428 18 appear appear VB cord-022526-j9kg00qf 3428 19 to to TO cord-022526-j9kg00qf 3428 20 be be VB cord-022526-j9kg00qf 3428 21 associated associate VBN cord-022526-j9kg00qf 3428 22 more more RBR cord-022526-j9kg00qf 3428 23 commonly commonly RB cord-022526-j9kg00qf 3428 24 with with IN cord-022526-j9kg00qf 3428 25 disease disease NN cord-022526-j9kg00qf 3428 26 than than IN cord-022526-j9kg00qf 3428 27 those those DT cord-022526-j9kg00qf 3428 28 in in IN cord-022526-j9kg00qf 3428 29 other other JJ cord-022526-j9kg00qf 3428 30 groups group NNS cord-022526-j9kg00qf 3428 31 . . . cord-022526-j9kg00qf 3429 1 Group Group NNP cord-022526-j9kg00qf 3429 2 B B NNP cord-022526-j9kg00qf 3429 3 includes include VBZ cord-022526-j9kg00qf 3429 4 S. S. NNP cord-022526-j9kg00qf 3429 5 typhimurium typhimurium NN cord-022526-j9kg00qf 3429 6 and and CC cord-022526-j9kg00qf 3429 7 S. S. NNP cord-022526-j9kg00qf 3429 8 agona agona NNP cord-022526-j9kg00qf 3429 9 , , , cord-022526-j9kg00qf 3429 10 two two CD cord-022526-j9kg00qf 3429 11 of of IN cord-022526-j9kg00qf 3429 12 the the DT cord-022526-j9kg00qf 3429 13 species specie NNS cord-022526-j9kg00qf 3429 14 most most RBS cord-022526-j9kg00qf 3429 15 frequently frequently RB cord-022526-j9kg00qf 3429 16 isolated isolate VBN cord-022526-j9kg00qf 3429 17 from from IN cord-022526-j9kg00qf 3429 18 horses horse NNS cord-022526-j9kg00qf 3429 19 . . . cord-022526-j9kg00qf 3430 1 1 1 LS cord-022526-j9kg00qf 3430 2 - - SYM cord-022526-j9kg00qf 3430 3 3 3 CD cord-022526-j9kg00qf 3430 4 S. S. NNP cord-022526-j9kg00qf 3430 5 typhimurium typhimurium NN cord-022526-j9kg00qf 3430 6 is be VBZ cord-022526-j9kg00qf 3430 7 the the DT cord-022526-j9kg00qf 3430 8 most most RBS cord-022526-j9kg00qf 3430 9 pathogenic pathogenic JJ cord-022526-j9kg00qf 3430 10 serotype serotype NN cord-022526-j9kg00qf 3430 11 in in IN cord-022526-j9kg00qf 3430 12 horses horse NNS cord-022526-j9kg00qf 3430 13 and and CC cord-022526-j9kg00qf 3430 14 is be VBZ cord-022526-j9kg00qf 3430 15 associated associate VBN cord-022526-j9kg00qf 3430 16 with with IN cord-022526-j9kg00qf 3430 17 a a DT cord-022526-j9kg00qf 3430 18 higher high JJR cord-022526-j9kg00qf 3430 19 case case NN cord-022526-j9kg00qf 3430 20 fatality fatality NN cord-022526-j9kg00qf 3430 21 rate rate NN cord-022526-j9kg00qf 3430 22 than than IN cord-022526-j9kg00qf 3430 23 other other JJ cord-022526-j9kg00qf 3430 24 species specie NNS cord-022526-j9kg00qf 3430 25 of of IN cord-022526-j9kg00qf 3430 26 Salmonella Salmonella NNP cord-022526-j9kg00qf 3430 27 . . . cord-022526-j9kg00qf 3431 1 1 1 LS cord-022526-j9kg00qf 3432 1 The the DT cord-022526-j9kg00qf 3432 2 number number NN cord-022526-j9kg00qf 3432 3 of of IN cord-022526-j9kg00qf 3432 4 horses horse NNS cord-022526-j9kg00qf 3432 5 that that WDT cord-022526-j9kg00qf 3432 6 are be VBP cord-022526-j9kg00qf 3432 7 infected infect VBN cord-022526-j9kg00qf 3432 8 inapparently inapparently RB cord-022526-j9kg00qf 3432 9 with with IN cord-022526-j9kg00qf 3432 10 and and CC cord-022526-j9kg00qf 3432 11 actively actively RB cord-022526-j9kg00qf 3432 12 shed shed VB cord-022526-j9kg00qf 3432 13 Salmonella salmonella NN cord-022526-j9kg00qf 3432 14 in in IN cord-022526-j9kg00qf 3432 15 their -PRON- PRP$ cord-022526-j9kg00qf 3432 16 feces fece NNS cord-022526-j9kg00qf 3432 17 has have VBZ cord-022526-j9kg00qf 3432 18 been be VBN cord-022526-j9kg00qf 3432 19 reported report VBN cord-022526-j9kg00qf 3432 20 to to TO cord-022526-j9kg00qf 3432 21 be be VB cord-022526-j9kg00qf 3432 22 as as RB cord-022526-j9kg00qf 3432 23 high high JJ cord-022526-j9kg00qf 3432 24 as as IN cord-022526-j9kg00qf 3432 25 10 10 CD cord-022526-j9kg00qf 3432 26 % % NN cord-022526-j9kg00qf 3432 27 to to TO cord-022526-j9kg00qf 3432 28 20 20 CD cord-022526-j9kg00qf 3432 29 % % NN cord-022526-j9kg00qf 3432 30 , , , cord-022526-j9kg00qf 3432 31 but but CC cord-022526-j9kg00qf 3432 32 actual actual JJ cord-022526-j9kg00qf 3432 33 prevalence prevalence NN cord-022526-j9kg00qf 3432 34 of of IN cord-022526-j9kg00qf 3432 35 Salmonella salmonella NN cord-022526-j9kg00qf 3432 36 - - HYPH cord-022526-j9kg00qf 3432 37 shedding shed VBG cord-022526-j9kg00qf 3432 38 in in IN cord-022526-j9kg00qf 3432 39 the the DT cord-022526-j9kg00qf 3432 40 general general JJ cord-022526-j9kg00qf 3432 41 horse horse NN cord-022526-j9kg00qf 3432 42 population population NN cord-022526-j9kg00qf 3432 43 is be VBZ cord-022526-j9kg00qf 3432 44 likely likely JJ cord-022526-j9kg00qf 3432 45 to to TO cord-022526-j9kg00qf 3432 46 be be VB cord-022526-j9kg00qf 3432 47 much much RB cord-022526-j9kg00qf 3432 48 lower low JJR cord-022526-j9kg00qf 3432 49 , , , cord-022526-j9kg00qf 3432 50 less less JJR cord-022526-j9kg00qf 3432 51 than than IN cord-022526-j9kg00qf 3432 52 1 1 CD cord-022526-j9kg00qf 3432 53 % % NN cord-022526-j9kg00qf 3432 54 to to TO cord-022526-j9kg00qf 3432 55 2 2 CD cord-022526-j9kg00qf 3432 56 % % NN cord-022526-j9kg00qf 3432 57 . . . cord-022526-j9kg00qf 3433 1 4 4 LS cord-022526-j9kg00qf 3433 2 Horses horse NNS cord-022526-j9kg00qf 3433 3 shedding shed VBG cord-022526-j9kg00qf 3433 4 salmonellae salmonellae NNP cord-022526-j9kg00qf 3433 5 are be VBP cord-022526-j9kg00qf 3433 6 a a DT cord-022526-j9kg00qf 3433 7 potential potential JJ cord-022526-j9kg00qf 3433 8 source source NN cord-022526-j9kg00qf 3433 9 of of IN cord-022526-j9kg00qf 3433 10 infection infection NN cord-022526-j9kg00qf 3433 11 to to IN cord-022526-j9kg00qf 3433 12 susceptible susceptible JJ cord-022526-j9kg00qf 3433 13 horses horse NNS cord-022526-j9kg00qf 3433 14 , , , cord-022526-j9kg00qf 3433 15 1,5 1,5 CD cord-022526-j9kg00qf 3433 16 as as IN cord-022526-j9kg00qf 3433 17 are be VBP cord-022526-j9kg00qf 3433 18 environmental environmental JJ cord-022526-j9kg00qf 3433 19 reservoirs reservoir NNS cord-022526-j9kg00qf 3433 20 . . . cord-022526-j9kg00qf 3434 1 [ [ -LRB- cord-022526-j9kg00qf 3434 2 6 6 CD cord-022526-j9kg00qf 3434 3 ] ] -RRB- cord-022526-j9kg00qf 3434 4 [ [ -LRB- cord-022526-j9kg00qf 3434 5 7 7 CD cord-022526-j9kg00qf 3434 6 ] ] -RRB- cord-022526-j9kg00qf 3434 7 [ [ -LRB- cord-022526-j9kg00qf 3434 8 8 8 CD cord-022526-j9kg00qf 3434 9 ] ] -RRB- cord-022526-j9kg00qf 3435 1 For for IN cord-022526-j9kg00qf 3435 2 these these DT cord-022526-j9kg00qf 3435 3 reasons reason NNS cord-022526-j9kg00qf 3435 4 , , , cord-022526-j9kg00qf 3435 5 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3435 6 is be VBZ cord-022526-j9kg00qf 3435 7 one one CD cord-022526-j9kg00qf 3435 8 of of IN cord-022526-j9kg00qf 3435 9 the the DT cord-022526-j9kg00qf 3435 10 most most RBS cord-022526-j9kg00qf 3435 11 common common JJ cord-022526-j9kg00qf 3435 12 nosocomial nosocomial JJ cord-022526-j9kg00qf 3435 13 diseases disease NNS cord-022526-j9kg00qf 3435 14 in in IN cord-022526-j9kg00qf 3435 15 horses horse NNS cord-022526-j9kg00qf 3435 16 . . . cord-022526-j9kg00qf 3436 1 Nosocomial nosocomial JJ cord-022526-j9kg00qf 3436 2 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3436 3 significantly significantly RB cord-022526-j9kg00qf 3436 4 affects affect VBZ cord-022526-j9kg00qf 3436 5 morbidity morbidity NN cord-022526-j9kg00qf 3436 6 and and CC cord-022526-j9kg00qf 3436 7 mortality mortality NN cord-022526-j9kg00qf 3436 8 in in IN cord-022526-j9kg00qf 3436 9 hospitalized hospitalize VBN cord-022526-j9kg00qf 3436 10 horses horse NNS cord-022526-j9kg00qf 3436 11 . . . cord-022526-j9kg00qf 3437 1 9 9 CD cord-022526-j9kg00qf 3438 1 The the DT cord-022526-j9kg00qf 3438 2 emergence emergence NN cord-022526-j9kg00qf 3438 3 of of IN cord-022526-j9kg00qf 3438 4 multidrug multidrug NN cord-022526-j9kg00qf 3438 5 resistance resistance NN cord-022526-j9kg00qf 3438 6 in in IN cord-022526-j9kg00qf 3438 7 equine equine JJ cord-022526-j9kg00qf 3438 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 3438 9 isolates isolate NNS cord-022526-j9kg00qf 3438 10 has have VBZ cord-022526-j9kg00qf 3438 11 been be VBN cord-022526-j9kg00qf 3438 12 a a DT cord-022526-j9kg00qf 3438 13 cause cause NN cord-022526-j9kg00qf 3438 14 of of IN cord-022526-j9kg00qf 3438 15 concern concern NN cord-022526-j9kg00qf 3438 16 because because IN cord-022526-j9kg00qf 3438 17 of of IN cord-022526-j9kg00qf 3438 18 the the DT cord-022526-j9kg00qf 3438 19 importance importance NN cord-022526-j9kg00qf 3438 20 of of IN cord-022526-j9kg00qf 3438 21 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3438 22 as as IN cord-022526-j9kg00qf 3438 23 a a DT cord-022526-j9kg00qf 3438 24 nosocomial nosocomial JJ cord-022526-j9kg00qf 3438 25 disease disease NN cord-022526-j9kg00qf 3438 26 and and CC cord-022526-j9kg00qf 3438 27 because because IN cord-022526-j9kg00qf 3438 28 Salmonella Salmonella NNP cord-022526-j9kg00qf 3438 29 represents represent VBZ cord-022526-j9kg00qf 3438 30 a a DT cord-022526-j9kg00qf 3438 31 significant significant JJ cord-022526-j9kg00qf 3438 32 zoonotic zoonotic JJ cord-022526-j9kg00qf 3438 33 pathogen pathogen NN cord-022526-j9kg00qf 3438 34 . . . cord-022526-j9kg00qf 3439 1 7 7 CD cord-022526-j9kg00qf 3439 2 , , , cord-022526-j9kg00qf 3439 3 [ [ -LRB- cord-022526-j9kg00qf 3439 4 10 10 CD cord-022526-j9kg00qf 3439 5 ] ] -RRB- cord-022526-j9kg00qf 3439 6 [ [ -LRB- cord-022526-j9kg00qf 3439 7 11 11 CD cord-022526-j9kg00qf 3439 8 ] ] -RRB- cord-022526-j9kg00qf 3439 9 [ [ -LRB- cord-022526-j9kg00qf 3439 10 12 12 CD cord-022526-j9kg00qf 3439 11 ] ] -RRB- cord-022526-j9kg00qf 3440 1 The the DT cord-022526-j9kg00qf 3440 2 virulence virulence NN cord-022526-j9kg00qf 3440 3 of of IN cord-022526-j9kg00qf 3440 4 the the DT cord-022526-j9kg00qf 3440 5 bacteria bacteria NNS cord-022526-j9kg00qf 3440 6 varies vary VBZ cord-022526-j9kg00qf 3440 7 tremendously tremendously RB cord-022526-j9kg00qf 3440 8 with with IN cord-022526-j9kg00qf 3440 9 serotype serotype NN cord-022526-j9kg00qf 3440 10 and and CC cord-022526-j9kg00qf 3440 11 even even RB cord-022526-j9kg00qf 3440 12 among among IN cord-022526-j9kg00qf 3440 13 strains strain NNS cord-022526-j9kg00qf 3440 14 of of IN cord-022526-j9kg00qf 3440 15 the the DT cord-022526-j9kg00qf 3440 16 same same JJ cord-022526-j9kg00qf 3440 17 serotype serotype NN cord-022526-j9kg00qf 3440 18 in in IN cord-022526-j9kg00qf 3440 19 part part NN cord-022526-j9kg00qf 3440 20 because because IN cord-022526-j9kg00qf 3440 21 of of IN cord-022526-j9kg00qf 3440 22 the the DT cord-022526-j9kg00qf 3440 23 important important JJ cord-022526-j9kg00qf 3440 24 role role NN cord-022526-j9kg00qf 3440 25 of of IN cord-022526-j9kg00qf 3440 26 host host NN cord-022526-j9kg00qf 3440 27 susceptibility susceptibility NN cord-022526-j9kg00qf 3440 28 in in IN cord-022526-j9kg00qf 3440 29 the the DT cord-022526-j9kg00qf 3440 30 pathogenicity pathogenicity NN cord-022526-j9kg00qf 3440 31 of of IN cord-022526-j9kg00qf 3440 32 particular particular JJ cord-022526-j9kg00qf 3440 33 organisms organism NNS cord-022526-j9kg00qf 3440 34 . . . cord-022526-j9kg00qf 3441 1 The the DT cord-022526-j9kg00qf 3441 2 infective infective JJ cord-022526-j9kg00qf 3441 3 dose dose NN cord-022526-j9kg00qf 3441 4 is be VBZ cord-022526-j9kg00qf 3441 5 generally generally RB cord-022526-j9kg00qf 3441 6 millions million NNS cord-022526-j9kg00qf 3441 7 of of IN cord-022526-j9kg00qf 3441 8 organisms organism NNS cord-022526-j9kg00qf 3441 9 inoculated inoculate VBN cord-022526-j9kg00qf 3441 10 orally orally RB cord-022526-j9kg00qf 3441 11 , , , cord-022526-j9kg00qf 3441 12 but but CC cord-022526-j9kg00qf 3441 13 various various JJ cord-022526-j9kg00qf 3441 14 environmental environmental JJ cord-022526-j9kg00qf 3441 15 and and CC cord-022526-j9kg00qf 3441 16 host host NN cord-022526-j9kg00qf 3441 17 factors factor NNS cord-022526-j9kg00qf 3441 18 can can MD cord-022526-j9kg00qf 3441 19 reduce reduce VB cord-022526-j9kg00qf 3441 20 the the DT cord-022526-j9kg00qf 3441 21 infective infective JJ cord-022526-j9kg00qf 3441 22 dose dose NN cord-022526-j9kg00qf 3441 23 to to IN cord-022526-j9kg00qf 3441 24 a a DT cord-022526-j9kg00qf 3441 25 few few JJ cord-022526-j9kg00qf 3441 26 thousand thousand CD cord-022526-j9kg00qf 3441 27 or or CC cord-022526-j9kg00qf 3441 28 even even RB cord-022526-j9kg00qf 3441 29 hundreds hundred NNS cord-022526-j9kg00qf 3441 30 of of IN cord-022526-j9kg00qf 3441 31 organisms organism NNS cord-022526-j9kg00qf 3441 32 . . . cord-022526-j9kg00qf 3442 1 [ [ -LRB- cord-022526-j9kg00qf 3442 2 13 13 CD cord-022526-j9kg00qf 3442 3 ] ] -RRB- cord-022526-j9kg00qf 3442 4 [ [ -LRB- cord-022526-j9kg00qf 3442 5 14 14 CD cord-022526-j9kg00qf 3442 6 ] ] -RRB- cord-022526-j9kg00qf 3442 7 [ [ -LRB- cord-022526-j9kg00qf 3442 8 15 15 CD cord-022526-j9kg00qf 3442 9 ] ] -RRB- cord-022526-j9kg00qf 3442 10 Environmental environmental JJ cord-022526-j9kg00qf 3442 11 factors factor NNS cord-022526-j9kg00qf 3442 12 or or CC cord-022526-j9kg00qf 3442 13 stresses stress NNS cord-022526-j9kg00qf 3442 14 that that WDT cord-022526-j9kg00qf 3442 15 increase increase VBP cord-022526-j9kg00qf 3442 16 susceptibility susceptibility NN cord-022526-j9kg00qf 3442 17 to to IN cord-022526-j9kg00qf 3442 18 Salmonella salmonella NN cord-022526-j9kg00qf 3442 19 infection infection NN cord-022526-j9kg00qf 3442 20 are be VBP cord-022526-j9kg00qf 3442 21 not not RB cord-022526-j9kg00qf 3442 22 well well RB cord-022526-j9kg00qf 3442 23 defined define VBN cord-022526-j9kg00qf 3442 24 , , , cord-022526-j9kg00qf 3442 25 but but CC cord-022526-j9kg00qf 3442 26 high high JJ cord-022526-j9kg00qf 3442 27 ambient ambient JJ cord-022526-j9kg00qf 3442 28 temperature temperature NN cord-022526-j9kg00qf 3442 29 , , , cord-022526-j9kg00qf 3442 30 for for IN cord-022526-j9kg00qf 3442 31 example example NN cord-022526-j9kg00qf 3442 32 , , , cord-022526-j9kg00qf 3442 33 is be VBZ cord-022526-j9kg00qf 3442 34 known know VBN cord-022526-j9kg00qf 3442 35 to to TO cord-022526-j9kg00qf 3442 36 increase increase VB cord-022526-j9kg00qf 3442 37 the the DT cord-022526-j9kg00qf 3442 38 prevalence prevalence NN cord-022526-j9kg00qf 3442 39 of of IN cord-022526-j9kg00qf 3442 40 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3442 41 in in IN cord-022526-j9kg00qf 3442 42 horses horse NNS cord-022526-j9kg00qf 3442 43 greatly greatly RB cord-022526-j9kg00qf 3442 44 . . . cord-022526-j9kg00qf 3443 1 Indeed indeed RB cord-022526-j9kg00qf 3443 2 , , , cord-022526-j9kg00qf 3443 3 the the DT cord-022526-j9kg00qf 3443 4 peak peak NN cord-022526-j9kg00qf 3443 5 incidence incidence NN cord-022526-j9kg00qf 3443 6 of of IN cord-022526-j9kg00qf 3443 7 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3443 8 in in IN cord-022526-j9kg00qf 3443 9 horses horse NNS cord-022526-j9kg00qf 3443 10 occurs occur VBZ cord-022526-j9kg00qf 3443 11 in in IN cord-022526-j9kg00qf 3443 12 late late JJ cord-022526-j9kg00qf 3443 13 summer summer NN cord-022526-j9kg00qf 3443 14 and and CC cord-022526-j9kg00qf 3443 15 fall fall NN cord-022526-j9kg00qf 3443 16 . . . cord-022526-j9kg00qf 3444 1 6 6 CD cord-022526-j9kg00qf 3444 2 , , , cord-022526-j9kg00qf 3444 3 14 14 CD cord-022526-j9kg00qf 3444 4 , , , cord-022526-j9kg00qf 3444 5 15 15 CD cord-022526-j9kg00qf 3444 6 Other other JJ cord-022526-j9kg00qf 3444 7 environmental environmental JJ cord-022526-j9kg00qf 3444 8 and and CC cord-022526-j9kg00qf 3444 9 host host NN cord-022526-j9kg00qf 3444 10 factors factor NNS cord-022526-j9kg00qf 3444 11 that that WDT cord-022526-j9kg00qf 3444 12 increase increase VBP cord-022526-j9kg00qf 3444 13 the the DT cord-022526-j9kg00qf 3444 14 risk risk NN cord-022526-j9kg00qf 3444 15 of of IN cord-022526-j9kg00qf 3444 16 Salmonella Salmonella NNP cord-022526-j9kg00qf 3444 17 infection infection NN cord-022526-j9kg00qf 3444 18 include include VBP cord-022526-j9kg00qf 3444 19 transportation transportation NN cord-022526-j9kg00qf 3444 20 , , , cord-022526-j9kg00qf 3444 21 antibiotic antibiotic JJ cord-022526-j9kg00qf 3444 22 administration administration NN cord-022526-j9kg00qf 3444 23 , , , cord-022526-j9kg00qf 3444 24 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3444 25 surgery surgery NN cord-022526-j9kg00qf 3444 26 , , , cord-022526-j9kg00qf 3444 27 general general JJ cord-022526-j9kg00qf 3444 28 anesthesia anesthesia NN cord-022526-j9kg00qf 3444 29 , , , cord-022526-j9kg00qf 3444 30 preexisting preexist VBG cord-022526-j9kg00qf 3444 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3444 32 disease disease NN cord-022526-j9kg00qf 3444 33 , , , cord-022526-j9kg00qf 3444 34 change change NN cord-022526-j9kg00qf 3444 35 in in IN cord-022526-j9kg00qf 3444 36 diet diet NN cord-022526-j9kg00qf 3444 37 , , , cord-022526-j9kg00qf 3444 38 and and CC cord-022526-j9kg00qf 3444 39 immunosuppression immunosuppression NN cord-022526-j9kg00qf 3444 40 . . . cord-022526-j9kg00qf 3445 1 1 1 CD cord-022526-j9kg00qf 3445 2 , , , cord-022526-j9kg00qf 3445 3 8 8 CD cord-022526-j9kg00qf 3445 4 , , , cord-022526-j9kg00qf 3445 5 15 15 CD cord-022526-j9kg00qf 3445 6 Host host NN cord-022526-j9kg00qf 3445 7 factors factor NNS cord-022526-j9kg00qf 3445 8 that that WDT cord-022526-j9kg00qf 3445 9 restrict restrict VBP cord-022526-j9kg00qf 3445 10 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3445 11 colonization colonization NN cord-022526-j9kg00qf 3445 12 and and CC cord-022526-j9kg00qf 3445 13 invasion invasion NN cord-022526-j9kg00qf 3445 14 by by IN cord-022526-j9kg00qf 3445 15 pathogens pathogen NNS cord-022526-j9kg00qf 3445 16 include include VBP cord-022526-j9kg00qf 3445 17 gastric gastric JJ cord-022526-j9kg00qf 3445 18 pH ph NN cord-022526-j9kg00qf 3445 19 , , , cord-022526-j9kg00qf 3445 20 commensal commensal JJ cord-022526-j9kg00qf 3445 21 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3445 22 flora flora NNS cord-022526-j9kg00qf 3445 23 , , , cord-022526-j9kg00qf 3445 24 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3445 25 motility motility NN cord-022526-j9kg00qf 3445 26 , , , cord-022526-j9kg00qf 3445 27 the the DT cord-022526-j9kg00qf 3445 28 mucosal mucosal JJ cord-022526-j9kg00qf 3445 29 barrier barrier NN cord-022526-j9kg00qf 3445 30 and and CC cord-022526-j9kg00qf 3445 31 mucosal mucosal JJ cord-022526-j9kg00qf 3445 32 immunity immunity NN cord-022526-j9kg00qf 3445 33 . . . cord-022526-j9kg00qf 3446 1 1 1 CD cord-022526-j9kg00qf 3446 2 , , , cord-022526-j9kg00qf 3446 3 16 16 CD cord-022526-j9kg00qf 3446 4 Gastric gastric JJ cord-022526-j9kg00qf 3446 5 acidity acidity NN cord-022526-j9kg00qf 3446 6 is be VBZ cord-022526-j9kg00qf 3446 7 an an DT cord-022526-j9kg00qf 3446 8 important important JJ cord-022526-j9kg00qf 3446 9 defense defense NN cord-022526-j9kg00qf 3446 10 mechanism mechanism NN cord-022526-j9kg00qf 3446 11 preventing prevent VBG cord-022526-j9kg00qf 3446 12 live live JJ cord-022526-j9kg00qf 3446 13 organisms organism NNS cord-022526-j9kg00qf 3446 14 from from IN cord-022526-j9kg00qf 3446 15 reaching reach VBG cord-022526-j9kg00qf 3446 16 the the DT cord-022526-j9kg00qf 3446 17 intestine intestine NN cord-022526-j9kg00qf 3446 18 . . . cord-022526-j9kg00qf 3447 1 Altering alter VBG cord-022526-j9kg00qf 3447 2 the the DT cord-022526-j9kg00qf 3447 3 gastric gastric JJ cord-022526-j9kg00qf 3447 4 pH ph NN cord-022526-j9kg00qf 3447 5 with with IN cord-022526-j9kg00qf 3447 6 histamine histamine JJ cord-022526-j9kg00qf 3447 7 2 2 CD cord-022526-j9kg00qf 3447 8 receptor receptor NN cord-022526-j9kg00qf 3447 9 antagonists antagonist NNS cord-022526-j9kg00qf 3447 10 , , , cord-022526-j9kg00qf 3447 11 for for IN cord-022526-j9kg00qf 3447 12 example example NN cord-022526-j9kg00qf 3447 13 , , , cord-022526-j9kg00qf 3447 14 may may MD cord-022526-j9kg00qf 3447 15 increase increase VB cord-022526-j9kg00qf 3447 16 susceptibility susceptibility NN cord-022526-j9kg00qf 3447 17 to to IN cord-022526-j9kg00qf 3447 18 infection infection NN cord-022526-j9kg00qf 3447 19 . . . cord-022526-j9kg00qf 3448 1 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3448 2 flora flora NNS cord-022526-j9kg00qf 3448 3 inhibits inhibit VBZ cord-022526-j9kg00qf 3448 4 the the DT cord-022526-j9kg00qf 3448 5 proliferation proliferation NN cord-022526-j9kg00qf 3448 6 and and CC cord-022526-j9kg00qf 3448 7 colonization colonization NN cord-022526-j9kg00qf 3448 8 of of IN cord-022526-j9kg00qf 3448 9 Salmonella Salmonella NNP cord-022526-j9kg00qf 3448 10 by by IN cord-022526-j9kg00qf 3448 11 secreting secrete VBG cord-022526-j9kg00qf 3448 12 bacteriocins bacteriocin NNS cord-022526-j9kg00qf 3448 13 , , , cord-022526-j9kg00qf 3448 14 short short JJ cord-022526-j9kg00qf 3448 15 - - HYPH cord-022526-j9kg00qf 3448 16 chain chain NN cord-022526-j9kg00qf 3448 17 fatty fatty JJ cord-022526-j9kg00qf 3448 18 acids acid NNS cord-022526-j9kg00qf 3448 19 , , , cord-022526-j9kg00qf 3448 20 and and CC cord-022526-j9kg00qf 3448 21 other other JJ cord-022526-j9kg00qf 3448 22 substances substance NNS cord-022526-j9kg00qf 3448 23 that that WDT cord-022526-j9kg00qf 3448 24 are be VBP cord-022526-j9kg00qf 3448 25 toxic toxic JJ cord-022526-j9kg00qf 3448 26 to to IN cord-022526-j9kg00qf 3448 27 Salmonella Salmonella NNP cord-022526-j9kg00qf 3448 28 . . . cord-022526-j9kg00qf 3449 1 In in IN cord-022526-j9kg00qf 3449 2 addition addition NN cord-022526-j9kg00qf 3449 3 , , , cord-022526-j9kg00qf 3449 4 elements element NNS cord-022526-j9kg00qf 3449 5 of of IN cord-022526-j9kg00qf 3449 6 the the DT cord-022526-j9kg00qf 3449 7 normal normal JJ cord-022526-j9kg00qf 3449 8 flora flora NNS cord-022526-j9kg00qf 3449 9 compete compete VBP cord-022526-j9kg00qf 3449 10 for for IN cord-022526-j9kg00qf 3449 11 nutrients nutrient NNS cord-022526-j9kg00qf 3449 12 and and CC cord-022526-j9kg00qf 3449 13 space space NN cord-022526-j9kg00qf 3449 14 , , , cord-022526-j9kg00qf 3449 15 especially especially RB cord-022526-j9kg00qf 3449 16 on on IN cord-022526-j9kg00qf 3449 17 the the DT cord-022526-j9kg00qf 3449 18 mucosa mucosa NN cord-022526-j9kg00qf 3449 19 . . . cord-022526-j9kg00qf 3450 1 16 16 CD cord-022526-j9kg00qf 3451 1 Being be VBG cord-022526-j9kg00qf 3451 2 predominantly predominantly RB cord-022526-j9kg00qf 3451 3 anaerobic anaerobic JJ cord-022526-j9kg00qf 3451 4 , , , cord-022526-j9kg00qf 3451 5 the the DT cord-022526-j9kg00qf 3451 6 normal normal JJ cord-022526-j9kg00qf 3451 7 flora flora NNS cord-022526-j9kg00qf 3451 8 maintain maintain VBP cord-022526-j9kg00qf 3451 9 a a DT cord-022526-j9kg00qf 3451 10 low low JJ cord-022526-j9kg00qf 3451 11 oxidationreduction oxidationreduction NN cord-022526-j9kg00qf 3451 12 potential potential NN cord-022526-j9kg00qf 3451 13 in in IN cord-022526-j9kg00qf 3451 14 the the DT cord-022526-j9kg00qf 3451 15 environment environment NN cord-022526-j9kg00qf 3451 16 of of IN cord-022526-j9kg00qf 3451 17 the the DT cord-022526-j9kg00qf 3451 18 large large JJ cord-022526-j9kg00qf 3451 19 intestine intestine NN cord-022526-j9kg00qf 3451 20 , , , cord-022526-j9kg00qf 3451 21 which which WDT cord-022526-j9kg00qf 3451 22 inhibits inhibit VBZ cord-022526-j9kg00qf 3451 23 the the DT cord-022526-j9kg00qf 3451 24 growth growth NN cord-022526-j9kg00qf 3451 25 of of IN cord-022526-j9kg00qf 3451 26 many many JJ cord-022526-j9kg00qf 3451 27 bacterial bacterial JJ cord-022526-j9kg00qf 3451 28 pathogens pathogen NNS cord-022526-j9kg00qf 3451 29 . . . cord-022526-j9kg00qf 3452 1 17 17 CD cord-022526-j9kg00qf 3453 1 The the DT cord-022526-j9kg00qf 3453 2 importance importance NN cord-022526-j9kg00qf 3453 3 of of IN cord-022526-j9kg00qf 3453 4 normal normal JJ cord-022526-j9kg00qf 3453 5 host host NN cord-022526-j9kg00qf 3453 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3453 7 ecology ecology NN cord-022526-j9kg00qf 3453 8 is be VBZ cord-022526-j9kg00qf 3453 9 illustrated illustrate VBN cord-022526-j9kg00qf 3453 10 by by IN cord-022526-j9kg00qf 3453 11 the the DT cord-022526-j9kg00qf 3453 12 fact fact NN cord-022526-j9kg00qf 3453 13 that that IN cord-022526-j9kg00qf 3453 14 disturbances disturbance NNS cord-022526-j9kg00qf 3453 15 of of IN cord-022526-j9kg00qf 3453 16 the the DT cord-022526-j9kg00qf 3453 17 colonic colonic JJ cord-022526-j9kg00qf 3453 18 flora flora NNS cord-022526-j9kg00qf 3453 19 with with IN cord-022526-j9kg00qf 3453 20 antibiotics antibiotic NNS cord-022526-j9kg00qf 3453 21 , , , cord-022526-j9kg00qf 3453 22 changes change NNS cord-022526-j9kg00qf 3453 23 in in IN cord-022526-j9kg00qf 3453 24 feed feed NN cord-022526-j9kg00qf 3453 25 , , , cord-022526-j9kg00qf 3453 26 ileus ileus NNP cord-022526-j9kg00qf 3453 27 , , , cord-022526-j9kg00qf 3453 28 or or CC cord-022526-j9kg00qf 3453 29 other other JJ cord-022526-j9kg00qf 3453 30 underlying underlie VBG cord-022526-j9kg00qf 3453 31 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3453 32 disease disease NN cord-022526-j9kg00qf 3453 33 greatly greatly RB cord-022526-j9kg00qf 3453 34 increase increase VBP cord-022526-j9kg00qf 3453 35 the the DT cord-022526-j9kg00qf 3453 36 susceptibility susceptibility NN cord-022526-j9kg00qf 3453 37 of of IN cord-022526-j9kg00qf 3453 38 the the DT cord-022526-j9kg00qf 3453 39 host host NN cord-022526-j9kg00qf 3453 40 to to IN cord-022526-j9kg00qf 3453 41 infection infection NN cord-022526-j9kg00qf 3453 42 by by IN cord-022526-j9kg00qf 3453 43 Salmonella Salmonella NNP cord-022526-j9kg00qf 3453 44 , , , cord-022526-j9kg00qf 3453 45 often often RB cord-022526-j9kg00qf 3453 46 resulting result VBG cord-022526-j9kg00qf 3453 47 in in IN cord-022526-j9kg00qf 3453 48 serious serious JJ cord-022526-j9kg00qf 3453 49 disease disease NN cord-022526-j9kg00qf 3453 50 . . . cord-022526-j9kg00qf 3454 1 The the DT cord-022526-j9kg00qf 3454 2 immune immune JJ cord-022526-j9kg00qf 3454 3 status status NN cord-022526-j9kg00qf 3454 4 of of IN cord-022526-j9kg00qf 3454 5 the the DT cord-022526-j9kg00qf 3454 6 host host NN cord-022526-j9kg00qf 3454 7 may may MD cord-022526-j9kg00qf 3454 8 be be VB cord-022526-j9kg00qf 3454 9 one one CD cord-022526-j9kg00qf 3454 10 of of IN cord-022526-j9kg00qf 3454 11 the the DT cord-022526-j9kg00qf 3454 12 most most RBS cord-022526-j9kg00qf 3454 13 important important JJ cord-022526-j9kg00qf 3454 14 factors factor NNS cord-022526-j9kg00qf 3454 15 determining determine VBG cord-022526-j9kg00qf 3454 16 not not RB cord-022526-j9kg00qf 3454 17 only only RB cord-022526-j9kg00qf 3454 18 the the DT cord-022526-j9kg00qf 3454 19 susceptibility susceptibility NN cord-022526-j9kg00qf 3454 20 to to IN cord-022526-j9kg00qf 3454 21 Salmonella salmonella NN cord-022526-j9kg00qf 3454 22 infections infection NNS cord-022526-j9kg00qf 3454 23 but but CC cord-022526-j9kg00qf 3454 24 also also RB cord-022526-j9kg00qf 3454 25 the the DT cord-022526-j9kg00qf 3454 26 degree degree NN cord-022526-j9kg00qf 3454 27 of of IN cord-022526-j9kg00qf 3454 28 invasion invasion NN cord-022526-j9kg00qf 3454 29 and and CC cord-022526-j9kg00qf 3454 30 subsequent subsequent JJ cord-022526-j9kg00qf 3454 31 outcome outcome NN cord-022526-j9kg00qf 3454 32 of of IN cord-022526-j9kg00qf 3454 33 the the DT cord-022526-j9kg00qf 3454 34 infection infection NN cord-022526-j9kg00qf 3454 35 . . . cord-022526-j9kg00qf 3455 1 Local local JJ cord-022526-j9kg00qf 3455 2 immunity immunity NN cord-022526-j9kg00qf 3455 3 , , , cord-022526-j9kg00qf 3455 4 such such JJ cord-022526-j9kg00qf 3455 5 as as IN cord-022526-j9kg00qf 3455 6 mucosal mucosal JJ cord-022526-j9kg00qf 3455 7 antibody antibody NN cord-022526-j9kg00qf 3455 8 secretion secretion NN cord-022526-j9kg00qf 3455 9 and and CC cord-022526-j9kg00qf 3455 10 enterocyte enterocyte NN cord-022526-j9kg00qf 3455 11 - - HYPH cord-022526-j9kg00qf 3455 12 derived derive VBN cord-022526-j9kg00qf 3455 13 cationic cationic JJ cord-022526-j9kg00qf 3455 14 peptides peptide NNS cord-022526-j9kg00qf 3455 15 , , , cord-022526-j9kg00qf 3455 16 prevents prevent VBZ cord-022526-j9kg00qf 3455 17 colonization colonization NN cord-022526-j9kg00qf 3455 18 of of IN cord-022526-j9kg00qf 3455 19 the the DT cord-022526-j9kg00qf 3455 20 mucosa mucosa NN cord-022526-j9kg00qf 3455 21 . . . cord-022526-j9kg00qf 3456 1 16 16 CD cord-022526-j9kg00qf 3456 2 , , , cord-022526-j9kg00qf 3456 3 18 18 CD cord-022526-j9kg00qf 3456 4 , , , cord-022526-j9kg00qf 3456 5 19 19 CD cord-022526-j9kg00qf 3456 6 Opsonizing Opsonizing NNP cord-022526-j9kg00qf 3456 7 antibodies antibody NNS cord-022526-j9kg00qf 3456 8 and and CC cord-022526-j9kg00qf 3456 9 activation activation NN cord-022526-j9kg00qf 3456 10 of of IN cord-022526-j9kg00qf 3456 11 the the DT cord-022526-j9kg00qf 3456 12 complement complement NN cord-022526-j9kg00qf 3456 13 cascade cascade NN cord-022526-j9kg00qf 3456 14 are be VBP cord-022526-j9kg00qf 3456 15 important important JJ cord-022526-j9kg00qf 3456 16 in in IN cord-022526-j9kg00qf 3456 17 fighting fight VBG cord-022526-j9kg00qf 3456 18 systemic systemic JJ cord-022526-j9kg00qf 3456 19 invasion invasion NN cord-022526-j9kg00qf 3456 20 by by IN cord-022526-j9kg00qf 3456 21 Salmonella Salmonella NNP cord-022526-j9kg00qf 3456 22 by by IN cord-022526-j9kg00qf 3456 23 increasing increase VBG cord-022526-j9kg00qf 3456 24 the the DT cord-022526-j9kg00qf 3456 25 efficiency efficiency NN cord-022526-j9kg00qf 3456 26 of of IN cord-022526-j9kg00qf 3456 27 phagocytosis phagocytosis NN cord-022526-j9kg00qf 3456 28 and and CC cord-022526-j9kg00qf 3456 29 by by IN cord-022526-j9kg00qf 3456 30 direct direct JJ cord-022526-j9kg00qf 3456 31 bactericidal bactericidal JJ cord-022526-j9kg00qf 3456 32 activity activity NN cord-022526-j9kg00qf 3456 33 . . . cord-022526-j9kg00qf 3457 1 Humoral Humoral NNP cord-022526-j9kg00qf 3457 2 immunity immunity NN cord-022526-j9kg00qf 3457 3 , , , cord-022526-j9kg00qf 3457 4 however however RB cord-022526-j9kg00qf 3457 5 , , , cord-022526-j9kg00qf 3457 6 is be VBZ cord-022526-j9kg00qf 3457 7 often often RB cord-022526-j9kg00qf 3457 8 ineffective ineffective JJ cord-022526-j9kg00qf 3457 9 in in IN cord-022526-j9kg00qf 3457 10 preventing prevent VBG cord-022526-j9kg00qf 3457 11 disease disease NN cord-022526-j9kg00qf 3457 12 and and CC cord-022526-j9kg00qf 3457 13 dissemination dissemination NN cord-022526-j9kg00qf 3457 14 once once IN cord-022526-j9kg00qf 3457 15 invasion invasion NN cord-022526-j9kg00qf 3457 16 occurs occur VBZ cord-022526-j9kg00qf 3457 17 and and CC cord-022526-j9kg00qf 3458 1 Salmonella salmonella NN cord-022526-j9kg00qf 3458 2 has have VBZ cord-022526-j9kg00qf 3458 3 established establish VBN cord-022526-j9kg00qf 3458 4 in in IN cord-022526-j9kg00qf 3458 5 its -PRON- PRP$ cord-022526-j9kg00qf 3458 6 intracellular intracellular JJ cord-022526-j9kg00qf 3458 7 niche niche NN cord-022526-j9kg00qf 3458 8 . . . cord-022526-j9kg00qf 3459 1 Following follow VBG cord-022526-j9kg00qf 3459 2 invasion invasion NN cord-022526-j9kg00qf 3459 3 , , , cord-022526-j9kg00qf 3459 4 Salmonella salmonella NN cord-022526-j9kg00qf 3459 5 is be VBZ cord-022526-j9kg00qf 3459 6 capable capable JJ cord-022526-j9kg00qf 3459 7 of of IN cord-022526-j9kg00qf 3459 8 surviving survive VBG cord-022526-j9kg00qf 3459 9 and and CC cord-022526-j9kg00qf 3459 10 multiplying multiply VBG cord-022526-j9kg00qf 3459 11 within within IN cord-022526-j9kg00qf 3459 12 macrophages macrophage NNS cord-022526-j9kg00qf 3459 13 , , , cord-022526-j9kg00qf 3459 14 rendering render VBG cord-022526-j9kg00qf 3459 15 humoral humoral JJ cord-022526-j9kg00qf 3459 16 ( ( -LRB- cord-022526-j9kg00qf 3459 17 noncellular noncellular JJ cord-022526-j9kg00qf 3459 18 ) ) -RRB- cord-022526-j9kg00qf 3459 19 immune immune JJ cord-022526-j9kg00qf 3459 20 systems system NNS cord-022526-j9kg00qf 3459 21 ineffective ineffective JJ cord-022526-j9kg00qf 3459 22 . . . cord-022526-j9kg00qf 3460 1 20 20 CD cord-022526-j9kg00qf 3460 2 , , , cord-022526-j9kg00qf 3460 3 21 21 CD cord-022526-j9kg00qf 3460 4 Specific specific JJ cord-022526-j9kg00qf 3460 5 cellular cellular JJ cord-022526-j9kg00qf 3460 6 immunity immunity NN cord-022526-j9kg00qf 3460 7 may may MD cord-022526-j9kg00qf 3460 8 be be VB cord-022526-j9kg00qf 3460 9 the the DT cord-022526-j9kg00qf 3460 10 most most RBS cord-022526-j9kg00qf 3460 11 effective effective JJ cord-022526-j9kg00qf 3460 12 defense defense NN cord-022526-j9kg00qf 3460 13 mechanism mechanism NN cord-022526-j9kg00qf 3460 14 in in IN cord-022526-j9kg00qf 3460 15 the the DT cord-022526-j9kg00qf 3460 16 host host NN cord-022526-j9kg00qf 3460 17 arsenal arsenal NN cord-022526-j9kg00qf 3460 18 against against IN cord-022526-j9kg00qf 3460 19 dissemination dissemination NN cord-022526-j9kg00qf 3460 20 and and CC cord-022526-j9kg00qf 3460 21 systemic systemic JJ cord-022526-j9kg00qf 3460 22 infection infection NN cord-022526-j9kg00qf 3460 23 by by IN cord-022526-j9kg00qf 3460 24 Salmonella Salmonella NNP cord-022526-j9kg00qf 3460 25 . . . cord-022526-j9kg00qf 3461 1 21 21 CD cord-022526-j9kg00qf 3461 2 , , , cord-022526-j9kg00qf 3461 3 22 22 CD cord-022526-j9kg00qf 3461 4 Oral oral JJ cord-022526-j9kg00qf 3461 5 inoculation inoculation NN cord-022526-j9kg00qf 3461 6 with with IN cord-022526-j9kg00qf 3461 7 small small JJ cord-022526-j9kg00qf 3461 8 numbers number NNS cord-022526-j9kg00qf 3461 9 of of IN cord-022526-j9kg00qf 3461 10 virulent virulent JJ cord-022526-j9kg00qf 3461 11 organisms organism NNS cord-022526-j9kg00qf 3461 12 may may MD cord-022526-j9kg00qf 3461 13 induce induce VB cord-022526-j9kg00qf 3461 14 protective protective JJ cord-022526-j9kg00qf 3461 15 immunity immunity NN cord-022526-j9kg00qf 3461 16 in in IN cord-022526-j9kg00qf 3461 17 horses horse NNS cord-022526-j9kg00qf 3461 18 and and CC cord-022526-j9kg00qf 3461 19 calves calf NNS cord-022526-j9kg00qf 3461 20 , , , cord-022526-j9kg00qf 3461 21 but but CC cord-022526-j9kg00qf 3461 22 the the DT cord-022526-j9kg00qf 3461 23 duration duration NN cord-022526-j9kg00qf 3461 24 of of IN cord-022526-j9kg00qf 3461 25 the the DT cord-022526-j9kg00qf 3461 26 immunity immunity NN cord-022526-j9kg00qf 3461 27 is be VBZ cord-022526-j9kg00qf 3461 28 not not RB cord-022526-j9kg00qf 3461 29 known know VBN cord-022526-j9kg00qf 3461 30 . . . cord-022526-j9kg00qf 3462 1 23 23 CD cord-022526-j9kg00qf 3462 2 , , , cord-022526-j9kg00qf 3462 3 24 24 CD cord-022526-j9kg00qf 3462 4 Oral oral JJ cord-022526-j9kg00qf 3462 5 and and CC cord-022526-j9kg00qf 3462 6 parenteral parenteral JJ cord-022526-j9kg00qf 3462 7 vaccines vaccine NNS cord-022526-j9kg00qf 3462 8 using use VBG cord-022526-j9kg00qf 3462 9 killed kill VBN cord-022526-j9kg00qf 3462 10 or or CC cord-022526-j9kg00qf 3462 11 attenuated attenuate VBN cord-022526-j9kg00qf 3462 12 organisms organism NNS cord-022526-j9kg00qf 3462 13 and and CC cord-022526-j9kg00qf 3462 14 bacterial bacterial JJ cord-022526-j9kg00qf 3462 15 products product NNS cord-022526-j9kg00qf 3462 16 have have VBP cord-022526-j9kg00qf 3462 17 been be VBN cord-022526-j9kg00qf 3462 18 promising promising JJ cord-022526-j9kg00qf 3462 19 but but CC cord-022526-j9kg00qf 3462 20 are be VBP cord-022526-j9kg00qf 3462 21 effective effective JJ cord-022526-j9kg00qf 3462 22 only only RB cord-022526-j9kg00qf 3462 23 against against IN cord-022526-j9kg00qf 3462 24 homologous homologous JJ cord-022526-j9kg00qf 3462 25 organisms organism NNS cord-022526-j9kg00qf 3462 26 and and CC cord-022526-j9kg00qf 3462 27 are be VBP cord-022526-j9kg00qf 3462 28 usually usually RB cord-022526-j9kg00qf 3462 29 not not RB cord-022526-j9kg00qf 3462 30 cross cross JJ cord-022526-j9kg00qf 3462 31 - - JJ cord-022526-j9kg00qf 3462 32 protective protective JJ cord-022526-j9kg00qf 3462 33 among among IN cord-022526-j9kg00qf 3462 34 different different JJ cord-022526-j9kg00qf 3462 35 serogroups serogroup NNS cord-022526-j9kg00qf 3462 36 . . . cord-022526-j9kg00qf 3463 1 [ [ -LRB- cord-022526-j9kg00qf 3463 2 23 23 CD cord-022526-j9kg00qf 3463 3 ] ] -RRB- cord-022526-j9kg00qf 3463 4 [ [ -LRB- cord-022526-j9kg00qf 3463 5 24 24 CD cord-022526-j9kg00qf 3463 6 ] ] -RRB- cord-022526-j9kg00qf 3464 1 [ [ -LRB- cord-022526-j9kg00qf 3464 2 25 25 CD cord-022526-j9kg00qf 3464 3 ] ] -RRB- cord-022526-j9kg00qf 3465 1 In in IN cord-022526-j9kg00qf 3465 2 adult adult NN cord-022526-j9kg00qf 3465 3 horses horse NNS cord-022526-j9kg00qf 3465 4 , , , cord-022526-j9kg00qf 3465 5 Salmonella Salmonella NNP cord-022526-j9kg00qf 3465 6 primarily primarily RB cord-022526-j9kg00qf 3465 7 infects infect VBZ cord-022526-j9kg00qf 3465 8 the the DT cord-022526-j9kg00qf 3465 9 cecum cecum NN cord-022526-j9kg00qf 3465 10 and and CC cord-022526-j9kg00qf 3465 11 proximal proximal JJ cord-022526-j9kg00qf 3465 12 colon colon NN cord-022526-j9kg00qf 3465 13 , , , cord-022526-j9kg00qf 3465 14 causing cause VBG cord-022526-j9kg00qf 3465 15 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3465 16 , , , cord-022526-j9kg00qf 3465 17 and and CC cord-022526-j9kg00qf 3465 18 the the DT cord-022526-j9kg00qf 3465 19 ability ability NN cord-022526-j9kg00qf 3465 20 to to TO cord-022526-j9kg00qf 3465 21 disseminate disseminate VB cord-022526-j9kg00qf 3465 22 beyond beyond IN cord-022526-j9kg00qf 3465 23 the the DT cord-022526-j9kg00qf 3465 24 intestine intestine NN cord-022526-j9kg00qf 3465 25 and and CC cord-022526-j9kg00qf 3465 26 cause cause VB cord-022526-j9kg00qf 3465 27 enteric enteric JJ cord-022526-j9kg00qf 3465 28 fever fever NN cord-022526-j9kg00qf 3465 29 is be VBZ cord-022526-j9kg00qf 3465 30 limited limit VBN cord-022526-j9kg00qf 3465 31 . . . cord-022526-j9kg00qf 3466 1 In in IN cord-022526-j9kg00qf 3466 2 foals foal NNS cord-022526-j9kg00qf 3466 3 , , , cord-022526-j9kg00qf 3466 4 however however RB cord-022526-j9kg00qf 3466 5 , , , cord-022526-j9kg00qf 3466 6 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3466 7 often often RB cord-022526-j9kg00qf 3466 8 is be VBZ cord-022526-j9kg00qf 3466 9 associated associate VBN cord-022526-j9kg00qf 3466 10 with with IN cord-022526-j9kg00qf 3466 11 septicemia septicemia NN cord-022526-j9kg00qf 3466 12 . . . cord-022526-j9kg00qf 3467 1 The the DT cord-022526-j9kg00qf 3467 2 ability ability NN cord-022526-j9kg00qf 3467 3 of of IN cord-022526-j9kg00qf 3467 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 3467 5 to to TO cord-022526-j9kg00qf 3467 6 cause cause VB cord-022526-j9kg00qf 3467 7 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3467 8 depends depend VBZ cord-022526-j9kg00qf 3467 9 on on IN cord-022526-j9kg00qf 3467 10 the the DT cord-022526-j9kg00qf 3467 11 ability ability NN cord-022526-j9kg00qf 3467 12 of of IN cord-022526-j9kg00qf 3467 13 the the DT cord-022526-j9kg00qf 3467 14 bacteria bacteria NNS cord-022526-j9kg00qf 3467 15 to to TO cord-022526-j9kg00qf 3467 16 invade invade VB cord-022526-j9kg00qf 3467 17 the the DT cord-022526-j9kg00qf 3467 18 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3467 19 mucosa mucosa NN cord-022526-j9kg00qf 3467 20 . . . cord-022526-j9kg00qf 3468 1 16 16 CD cord-022526-j9kg00qf 3468 2 , , , cord-022526-j9kg00qf 3468 3 20 20 CD cord-022526-j9kg00qf 3468 4 Invasion invasion NN cord-022526-j9kg00qf 3468 5 of of IN cord-022526-j9kg00qf 3468 6 the the DT cord-022526-j9kg00qf 3468 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3468 8 mucosa mucosa NN cord-022526-j9kg00qf 3468 9 occurs occur VBZ cord-022526-j9kg00qf 3468 10 preferentially preferentially RB cord-022526-j9kg00qf 3468 11 through through IN cord-022526-j9kg00qf 3468 12 specialized specialized JJ cord-022526-j9kg00qf 3468 13 enterocytes enterocyte NNS cord-022526-j9kg00qf 3468 14 called call VBN cord-022526-j9kg00qf 3468 15 M M NNP cord-022526-j9kg00qf 3468 16 cells cell NNS cord-022526-j9kg00qf 3468 17 that that WDT cord-022526-j9kg00qf 3468 18 overlay overlay VBP cord-022526-j9kg00qf 3468 19 intestinal intestinal JJ cord-022526-j9kg00qf 3468 20 lymphoid lymphoid JJ cord-022526-j9kg00qf 3468 21 tissues tissue NNS cord-022526-j9kg00qf 3468 22 such such JJ cord-022526-j9kg00qf 3468 23 as as IN cord-022526-j9kg00qf 3468 24 Peyer Peyer NNP cord-022526-j9kg00qf 3468 25 's 's POS cord-022526-j9kg00qf 3468 26 patches patch NNS cord-022526-j9kg00qf 3468 27 in in IN cord-022526-j9kg00qf 3468 28 nonequine nonequine NN cord-022526-j9kg00qf 3468 29 species specie NNS cord-022526-j9kg00qf 3468 30 . . . cord-022526-j9kg00qf 3469 1 A a DT cord-022526-j9kg00qf 3469 2 variety variety NN cord-022526-j9kg00qf 3469 3 of of IN cord-022526-j9kg00qf 3469 4 enteric enteric JJ cord-022526-j9kg00qf 3469 5 pathogens pathogen NNS cord-022526-j9kg00qf 3469 6 exploit exploit VBP cord-022526-j9kg00qf 3469 7 M m CD cord-022526-j9kg00qf 3469 8 cells cell NNS cord-022526-j9kg00qf 3469 9 during during IN cord-022526-j9kg00qf 3469 10 infection infection NN cord-022526-j9kg00qf 3469 11 of of IN cord-022526-j9kg00qf 3469 12 intestinal intestinal JJ cord-022526-j9kg00qf 3469 13 tissue tissue NN cord-022526-j9kg00qf 3469 14 . . . cord-022526-j9kg00qf 3470 1 26 26 CD cord-022526-j9kg00qf 3470 2 Invasion invasion NN cord-022526-j9kg00qf 3470 3 of of IN cord-022526-j9kg00qf 3470 4 the the DT cord-022526-j9kg00qf 3470 5 epithelium epithelium NN cord-022526-j9kg00qf 3470 6 occurs occur VBZ cord-022526-j9kg00qf 3470 7 by by IN cord-022526-j9kg00qf 3470 8 self self NN cord-022526-j9kg00qf 3470 9 - - HYPH cord-022526-j9kg00qf 3470 10 induced induce VBN cord-022526-j9kg00qf 3470 11 uptake uptake NN cord-022526-j9kg00qf 3470 12 via via IN cord-022526-j9kg00qf 3470 13 the the DT cord-022526-j9kg00qf 3470 14 apical apical JJ cord-022526-j9kg00qf 3470 15 membrane membrane NN cord-022526-j9kg00qf 3470 16 of of IN cord-022526-j9kg00qf 3470 17 the the DT cord-022526-j9kg00qf 3470 18 M M NNP cord-022526-j9kg00qf 3470 19 cell cell NN cord-022526-j9kg00qf 3470 20 , , , cord-022526-j9kg00qf 3470 21 often often RB cord-022526-j9kg00qf 3470 22 killing kill VBG cord-022526-j9kg00qf 3470 23 the the DT cord-022526-j9kg00qf 3470 24 cell cell NN cord-022526-j9kg00qf 3470 25 in in IN cord-022526-j9kg00qf 3470 26 the the DT cord-022526-j9kg00qf 3470 27 process process NN cord-022526-j9kg00qf 3470 28 . . . cord-022526-j9kg00qf 3471 1 20 20 CD cord-022526-j9kg00qf 3471 2 Salmonellae Salmonellae NNP cord-022526-j9kg00qf 3471 3 then then RB cord-022526-j9kg00qf 3471 4 invade invade VBP cord-022526-j9kg00qf 3471 5 neighboring neighboring NN cord-022526-j9kg00qf 3471 6 cells cell NNS cord-022526-j9kg00qf 3471 7 via via IN cord-022526-j9kg00qf 3471 8 the the DT cord-022526-j9kg00qf 3471 9 basolateral basolateral JJ cord-022526-j9kg00qf 3471 10 membrane membrane NN cord-022526-j9kg00qf 3471 11 , , , cord-022526-j9kg00qf 3471 12 eventually eventually RB cord-022526-j9kg00qf 3471 13 spreading spread VBG cord-022526-j9kg00qf 3471 14 the the DT cord-022526-j9kg00qf 3471 15 destruction destruction NN cord-022526-j9kg00qf 3471 16 of of IN cord-022526-j9kg00qf 3471 17 the the DT cord-022526-j9kg00qf 3471 18 epithelium epithelium NN cord-022526-j9kg00qf 3471 19 beyond beyond IN cord-022526-j9kg00qf 3471 20 the the DT cord-022526-j9kg00qf 3471 21 principle principle JJ cord-022526-j9kg00qf 3471 22 area area NN cord-022526-j9kg00qf 3471 23 of of IN cord-022526-j9kg00qf 3471 24 attack attack NN cord-022526-j9kg00qf 3471 25 . . . cord-022526-j9kg00qf 3472 1 Virulent virulent JJ cord-022526-j9kg00qf 3472 2 salmonellae salmonella NNS cord-022526-j9kg00qf 3472 3 have have VBP cord-022526-j9kg00qf 3472 4 a a DT cord-022526-j9kg00qf 3472 5 well well RB cord-022526-j9kg00qf 3472 6 - - HYPH cord-022526-j9kg00qf 3472 7 developed develop VBN cord-022526-j9kg00qf 3472 8 invasion invasion NN cord-022526-j9kg00qf 3472 9 mechanism mechanism NN cord-022526-j9kg00qf 3472 10 involving involve VBG cord-022526-j9kg00qf 3472 11 generation generation NN cord-022526-j9kg00qf 3472 12 of of IN cord-022526-j9kg00qf 3472 13 an an DT cord-022526-j9kg00qf 3472 14 apparatus apparatus NN cord-022526-j9kg00qf 3472 15 called call VBN cord-022526-j9kg00qf 3472 16 a a DT cord-022526-j9kg00qf 3472 17 type type NN cord-022526-j9kg00qf 3472 18 III iii CD cord-022526-j9kg00qf 3472 19 secretory secretory NN cord-022526-j9kg00qf 3472 20 system system NN cord-022526-j9kg00qf 3472 21 that that WDT cord-022526-j9kg00qf 3472 22 enables enable VBZ cord-022526-j9kg00qf 3472 23 virulence virulence NN cord-022526-j9kg00qf 3472 24 gene gene NN cord-022526-j9kg00qf 3472 25 products product NNS cord-022526-j9kg00qf 3472 26 to to TO cord-022526-j9kg00qf 3472 27 be be VB cord-022526-j9kg00qf 3472 28 injected inject VBN cord-022526-j9kg00qf 3472 29 directly directly RB cord-022526-j9kg00qf 3472 30 into into IN cord-022526-j9kg00qf 3472 31 enterocytes enterocyte NNS cord-022526-j9kg00qf 3472 32 . . . cord-022526-j9kg00qf 3473 1 27 27 CD cord-022526-j9kg00qf 3473 2 Virulence virulence NN cord-022526-j9kg00qf 3473 3 proteins protein NNS cord-022526-j9kg00qf 3473 4 injected inject VBN cord-022526-j9kg00qf 3473 5 by by IN cord-022526-j9kg00qf 3473 6 salmonellae salmonellae NNP cord-022526-j9kg00qf 3473 7 into into IN cord-022526-j9kg00qf 3473 8 enterocytes enterocytes NNPS cord-022526-j9kg00qf 3473 9 engage engage VBP cord-022526-j9kg00qf 3473 10 the the DT cord-022526-j9kg00qf 3473 11 cellular cellular JJ cord-022526-j9kg00qf 3473 12 machinery machinery NN cord-022526-j9kg00qf 3473 13 and and CC cord-022526-j9kg00qf 3473 14 induce induce VB cord-022526-j9kg00qf 3473 15 the the DT cord-022526-j9kg00qf 3473 16 cell cell NN cord-022526-j9kg00qf 3473 17 to to TO cord-022526-j9kg00qf 3473 18 engulf engulf VB cord-022526-j9kg00qf 3473 19 the the DT cord-022526-j9kg00qf 3473 20 bacteria bacteria NNS cord-022526-j9kg00qf 3473 21 by by IN cord-022526-j9kg00qf 3473 22 macropinocytosis macropinocytosis NNP cord-022526-j9kg00qf 3473 23 . . . cord-022526-j9kg00qf 3474 1 Salmonella salmonella NN cord-022526-j9kg00qf 3474 2 virulence virulence NN cord-022526-j9kg00qf 3474 3 gene gene NN cord-022526-j9kg00qf 3474 4 products product NNS cord-022526-j9kg00qf 3474 5 also also RB cord-022526-j9kg00qf 3474 6 induce induce VBP cord-022526-j9kg00qf 3474 7 enterocyte enterocyte NNP cord-022526-j9kg00qf 3474 8 chloride chloride NN cord-022526-j9kg00qf 3474 9 and and CC cord-022526-j9kg00qf 3474 10 fluid fluid JJ cord-022526-j9kg00qf 3474 11 secretion secretion NN cord-022526-j9kg00qf 3474 12 and and CC cord-022526-j9kg00qf 3474 13 upregulate upregulate VB cord-022526-j9kg00qf 3474 14 enterocyte enterocyte NNP cord-022526-j9kg00qf 3474 15 transcription transcription NN cord-022526-j9kg00qf 3474 16 of of IN cord-022526-j9kg00qf 3474 17 inflammatory inflammatory JJ cord-022526-j9kg00qf 3474 18 cytokines cytokine NNS cord-022526-j9kg00qf 3474 19 ( ( -LRB- cord-022526-j9kg00qf 3474 20 tumor tumor NN cord-022526-j9kg00qf 3474 21 necrosis necrosis NN cord-022526-j9kg00qf 3474 22 factor factor NN cord-022526-j9kg00qf 3474 23 α α NN cord-022526-j9kg00qf 3474 24 and and CC cord-022526-j9kg00qf 3474 25 interleukin-1β interleukin-1β NNP cord-022526-j9kg00qf 3474 26 ) ) -RRB- cord-022526-j9kg00qf 3474 27 and and CC cord-022526-j9kg00qf 3474 28 chemokines chemokine NNS cord-022526-j9kg00qf 3474 29 that that WDT cord-022526-j9kg00qf 3474 30 trigger trigger VBP cord-022526-j9kg00qf 3474 31 a a DT cord-022526-j9kg00qf 3474 32 mucosal mucosal JJ cord-022526-j9kg00qf 3474 33 inflammatory inflammatory JJ cord-022526-j9kg00qf 3474 34 response response NN cord-022526-j9kg00qf 3474 35 . . . cord-022526-j9kg00qf 3475 1 20 20 CD cord-022526-j9kg00qf 3475 2 , , , cord-022526-j9kg00qf 3475 3 27 27 CD cord-022526-j9kg00qf 3475 4 , , , cord-022526-j9kg00qf 3475 5 28 28 CD cord-022526-j9kg00qf 3475 6 After after IN cord-022526-j9kg00qf 3475 7 salmonellae salmonella NNS cord-022526-j9kg00qf 3475 8 invade invade VBP cord-022526-j9kg00qf 3475 9 the the DT cord-022526-j9kg00qf 3475 10 mucosa mucosa NN cord-022526-j9kg00qf 3475 11 , , , cord-022526-j9kg00qf 3475 12 they -PRON- PRP cord-022526-j9kg00qf 3475 13 are be VBP cord-022526-j9kg00qf 3475 14 phagocytosed phagocytose VBN cord-022526-j9kg00qf 3475 15 quickly quickly RB cord-022526-j9kg00qf 3475 16 by by IN cord-022526-j9kg00qf 3475 17 macrophages macrophage NNS cord-022526-j9kg00qf 3475 18 and and CC cord-022526-j9kg00qf 3475 19 dendritic dendritic JJ cord-022526-j9kg00qf 3475 20 cells cell NNS cord-022526-j9kg00qf 3475 21 in in IN cord-022526-j9kg00qf 3475 22 the the DT cord-022526-j9kg00qf 3475 23 lamina lamina JJ cord-022526-j9kg00qf 3475 24 propria propria NN cord-022526-j9kg00qf 3475 25 and and CC cord-022526-j9kg00qf 3475 26 lymphoid lymphoid JJ cord-022526-j9kg00qf 3475 27 tissues tissue NNS cord-022526-j9kg00qf 3475 28 . . . cord-022526-j9kg00qf 3476 1 The the DT cord-022526-j9kg00qf 3476 2 ability ability NN cord-022526-j9kg00qf 3476 3 of of IN cord-022526-j9kg00qf 3476 4 salmonellae salmonella NNS cord-022526-j9kg00qf 3476 5 to to TO cord-022526-j9kg00qf 3476 6 disseminate disseminate VB cord-022526-j9kg00qf 3476 7 systemically systemically RB cord-022526-j9kg00qf 3476 8 and and CC cord-022526-j9kg00qf 3476 9 cause cause VB cord-022526-j9kg00qf 3476 10 enteric enteric JJ cord-022526-j9kg00qf 3476 11 fever fever NN cord-022526-j9kg00qf 3476 12 is be VBZ cord-022526-j9kg00qf 3476 13 associated associate VBN cord-022526-j9kg00qf 3476 14 with with IN cord-022526-j9kg00qf 3476 15 the the DT cord-022526-j9kg00qf 3476 16 ability ability NN cord-022526-j9kg00qf 3476 17 to to TO cord-022526-j9kg00qf 3476 18 survive survive VB cord-022526-j9kg00qf 3476 19 and and CC cord-022526-j9kg00qf 3476 20 proliferate proliferate VB cord-022526-j9kg00qf 3476 21 in in IN cord-022526-j9kg00qf 3476 22 macrophages macrophage NNS cord-022526-j9kg00qf 3476 23 . . . cord-022526-j9kg00qf 3477 1 Indeed indeed RB cord-022526-j9kg00qf 3477 2 , , , cord-022526-j9kg00qf 3477 3 phagocytes phagocyte NNS cord-022526-j9kg00qf 3477 4 have have VBP cord-022526-j9kg00qf 3477 5 an an DT cord-022526-j9kg00qf 3477 6 important important JJ cord-022526-j9kg00qf 3477 7 role role NN cord-022526-j9kg00qf 3477 8 in in IN cord-022526-j9kg00qf 3477 9 dissemination dissemination NN cord-022526-j9kg00qf 3477 10 of of IN cord-022526-j9kg00qf 3477 11 the the DT cord-022526-j9kg00qf 3477 12 pathogen pathogen NN cord-022526-j9kg00qf 3477 13 to to IN cord-022526-j9kg00qf 3477 14 blood blood NN cord-022526-j9kg00qf 3477 15 , , , cord-022526-j9kg00qf 3477 16 lymph lymph NN cord-022526-j9kg00qf 3477 17 nodes node NNS cord-022526-j9kg00qf 3477 18 , , , cord-022526-j9kg00qf 3477 19 liver liver NN cord-022526-j9kg00qf 3477 20 , , , cord-022526-j9kg00qf 3477 21 and and CC cord-022526-j9kg00qf 3477 22 spleen spleen NNS cord-022526-j9kg00qf 3477 23 . . . cord-022526-j9kg00qf 3478 1 Most Most JJS cord-022526-j9kg00qf 3478 2 salmonellae salmonella NNS cord-022526-j9kg00qf 3478 3 in in IN cord-022526-j9kg00qf 3478 4 the the DT cord-022526-j9kg00qf 3478 5 blood blood NN cord-022526-j9kg00qf 3478 6 and and CC cord-022526-j9kg00qf 3478 7 tissues tissue NNS cord-022526-j9kg00qf 3478 8 of of IN cord-022526-j9kg00qf 3478 9 infected infected JJ cord-022526-j9kg00qf 3478 10 animals animal NNS cord-022526-j9kg00qf 3478 11 that that WDT cord-022526-j9kg00qf 3478 12 are be VBP cord-022526-j9kg00qf 3478 13 competent competent JJ cord-022526-j9kg00qf 3478 14 to to TO cord-022526-j9kg00qf 3478 15 cause cause VB cord-022526-j9kg00qf 3478 16 enteric enteric JJ cord-022526-j9kg00qf 3478 17 fever fever NN cord-022526-j9kg00qf 3478 18 are be VBP cord-022526-j9kg00qf 3478 19 within within IN cord-022526-j9kg00qf 3478 20 phagocytic phagocytic JJ cord-022526-j9kg00qf 3478 21 cells cell NNS cord-022526-j9kg00qf 3478 22 . . . cord-022526-j9kg00qf 3479 1 29 29 CD cord-022526-j9kg00qf 3480 1 In in IN cord-022526-j9kg00qf 3480 2 adult adult NN cord-022526-j9kg00qf 3480 3 horses horse NNS cord-022526-j9kg00qf 3480 4 with with IN cord-022526-j9kg00qf 3480 5 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3480 6 , , , cord-022526-j9kg00qf 3480 7 dissemination dissemination NN cord-022526-j9kg00qf 3480 8 appears appear VBZ cord-022526-j9kg00qf 3480 9 to to TO cord-022526-j9kg00qf 3480 10 be be VB cord-022526-j9kg00qf 3480 11 limited limit VBN cord-022526-j9kg00qf 3480 12 to to IN cord-022526-j9kg00qf 3480 13 the the DT cord-022526-j9kg00qf 3480 14 intestine intestine NN cord-022526-j9kg00qf 3480 15 and and CC cord-022526-j9kg00qf 3480 16 mesenteric mesenteric JJ cord-022526-j9kg00qf 3480 17 lymph lymph NN cord-022526-j9kg00qf 3480 18 nodes node NNS cord-022526-j9kg00qf 3480 19 , , , cord-022526-j9kg00qf 3480 20 and and CC cord-022526-j9kg00qf 3480 21 Salmonella Salmonella NNP cord-022526-j9kg00qf 3480 22 rarely rarely RB cord-022526-j9kg00qf 3480 23 is be VBZ cord-022526-j9kg00qf 3480 24 cultured culture VBN cord-022526-j9kg00qf 3480 25 from from IN cord-022526-j9kg00qf 3480 26 blood blood NN cord-022526-j9kg00qf 3480 27 . . . cord-022526-j9kg00qf 3481 1 However however RB cord-022526-j9kg00qf 3481 2 , , , cord-022526-j9kg00qf 3481 3 in in IN cord-022526-j9kg00qf 3481 4 foals foal NNS cord-022526-j9kg00qf 3481 5 and and CC cord-022526-j9kg00qf 3481 6 in in IN cord-022526-j9kg00qf 3481 7 some some DT cord-022526-j9kg00qf 3481 8 adults adult NNS cord-022526-j9kg00qf 3481 9 , , , cord-022526-j9kg00qf 3481 10 Salmonella salmonella NN cord-022526-j9kg00qf 3481 11 causes cause VBZ cord-022526-j9kg00qf 3481 12 an an DT cord-022526-j9kg00qf 3481 13 enteric enteric JJ cord-022526-j9kg00qf 3481 14 feverlike feverlike NN cord-022526-j9kg00qf 3481 15 disease disease NN cord-022526-j9kg00qf 3481 16 with with IN cord-022526-j9kg00qf 3481 17 dissemination dissemination NN cord-022526-j9kg00qf 3481 18 to to IN cord-022526-j9kg00qf 3481 19 mesenteric mesenteric JJ cord-022526-j9kg00qf 3481 20 lymph lymph NN cord-022526-j9kg00qf 3481 21 nodes node NNS cord-022526-j9kg00qf 3481 22 , , , cord-022526-j9kg00qf 3481 23 liver liver NN cord-022526-j9kg00qf 3481 24 , , , cord-022526-j9kg00qf 3481 25 spleen spleen NNS cord-022526-j9kg00qf 3481 26 , , , cord-022526-j9kg00qf 3481 27 and and CC cord-022526-j9kg00qf 3481 28 blood blood NN cord-022526-j9kg00qf 3481 29 . . . cord-022526-j9kg00qf 3482 1 Salmonella salmonella NN cord-022526-j9kg00qf 3482 2 organisms organism NNS cord-022526-j9kg00qf 3482 3 require require VBP cord-022526-j9kg00qf 3482 4 specific specific JJ cord-022526-j9kg00qf 3482 5 virulence virulence NN cord-022526-j9kg00qf 3482 6 gene gene NN cord-022526-j9kg00qf 3482 7 clusters cluster NNS cord-022526-j9kg00qf 3482 8 encoded encode VBN cord-022526-j9kg00qf 3482 9 on on IN cord-022526-j9kg00qf 3482 10 the the DT cord-022526-j9kg00qf 3482 11 chromosome chromosome NN cord-022526-j9kg00qf 3482 12 or or CC cord-022526-j9kg00qf 3482 13 on on IN cord-022526-j9kg00qf 3482 14 plasmids plasmid NNS cord-022526-j9kg00qf 3482 15 for for IN cord-022526-j9kg00qf 3482 16 intracellular intracellular JJ cord-022526-j9kg00qf 3482 17 survival survival NN cord-022526-j9kg00qf 3482 18 in in IN cord-022526-j9kg00qf 3482 19 macrophages macrophage NNS cord-022526-j9kg00qf 3482 20 . . . cord-022526-j9kg00qf 3483 1 20 20 CD cord-022526-j9kg00qf 3484 1 Some some DT cord-022526-j9kg00qf 3484 2 of of IN cord-022526-j9kg00qf 3484 3 these these DT cord-022526-j9kg00qf 3484 4 genes gene NNS cord-022526-j9kg00qf 3484 5 are be VBP cord-022526-j9kg00qf 3484 6 sensors sensor NNS cord-022526-j9kg00qf 3484 7 that that WDT cord-022526-j9kg00qf 3484 8 signal signal VBP cord-022526-j9kg00qf 3484 9 the the DT cord-022526-j9kg00qf 3484 10 bacteria bacteria NNS cord-022526-j9kg00qf 3484 11 that that WDT cord-022526-j9kg00qf 3484 12 it -PRON- PRP cord-022526-j9kg00qf 3484 13 has have VBZ cord-022526-j9kg00qf 3484 14 entered enter VBN cord-022526-j9kg00qf 3484 15 an an DT cord-022526-j9kg00qf 3484 16 intracellular intracellular JJ cord-022526-j9kg00qf 3484 17 environment environment NN cord-022526-j9kg00qf 3484 18 and and CC cord-022526-j9kg00qf 3484 19 turn turn VB cord-022526-j9kg00qf 3484 20 on on RP cord-022526-j9kg00qf 3484 21 genes gene NNS cord-022526-j9kg00qf 3484 22 required require VBN cord-022526-j9kg00qf 3484 23 for for IN cord-022526-j9kg00qf 3484 24 intracellular intracellular JJ cord-022526-j9kg00qf 3484 25 survival survival NN cord-022526-j9kg00qf 3484 26 . . . cord-022526-j9kg00qf 3485 1 Others other NNS cord-022526-j9kg00qf 3485 2 , , , cord-022526-j9kg00qf 3485 3 like like IN cord-022526-j9kg00qf 3485 4 invasion invasion NN cord-022526-j9kg00qf 3485 5 genes gene NNS cord-022526-j9kg00qf 3485 6 , , , cord-022526-j9kg00qf 3485 7 are be VBP cord-022526-j9kg00qf 3485 8 transported transport VBN cord-022526-j9kg00qf 3485 9 from from IN cord-022526-j9kg00qf 3485 10 the the DT cord-022526-j9kg00qf 3485 11 bacteria bacteria NNS cord-022526-j9kg00qf 3485 12 and and CC cord-022526-j9kg00qf 3485 13 injected inject VBD cord-022526-j9kg00qf 3485 14 into into IN cord-022526-j9kg00qf 3485 15 macrophage macrophage NN cord-022526-j9kg00qf 3485 16 cytosol cytosol NN cord-022526-j9kg00qf 3485 17 by by IN cord-022526-j9kg00qf 3485 18 a a DT cord-022526-j9kg00qf 3485 19 type type NN cord-022526-j9kg00qf 3485 20 III iii CD cord-022526-j9kg00qf 3485 21 secretory secretory NN cord-022526-j9kg00qf 3485 22 system system NN cord-022526-j9kg00qf 3485 23 to to TO cord-022526-j9kg00qf 3485 24 prevent prevent VB cord-022526-j9kg00qf 3485 25 phagosome phagosome NN cord-022526-j9kg00qf 3485 26 / / SYM cord-022526-j9kg00qf 3485 27 lysosome lysosome NN cord-022526-j9kg00qf 3485 28 fusion fusion NN cord-022526-j9kg00qf 3485 29 and and CC cord-022526-j9kg00qf 3485 30 subvert subvert VB cord-022526-j9kg00qf 3485 31 other other JJ cord-022526-j9kg00qf 3485 32 essential essential JJ cord-022526-j9kg00qf 3485 33 macrophage macrophage NN cord-022526-j9kg00qf 3485 34 killing killing NN cord-022526-j9kg00qf 3485 35 mechanisms mechanism NNS cord-022526-j9kg00qf 3485 36 . . . cord-022526-j9kg00qf 3486 1 Salmonellae Salmonellae NNP cord-022526-j9kg00qf 3486 2 also also RB cord-022526-j9kg00qf 3486 3 possess possess VBP cord-022526-j9kg00qf 3486 4 multiple multiple JJ cord-022526-j9kg00qf 3486 5 genes gene NNS cord-022526-j9kg00qf 3486 6 that that WDT cord-022526-j9kg00qf 3486 7 confer confer VBP cord-022526-j9kg00qf 3486 8 resistance resistance NN cord-022526-j9kg00qf 3486 9 to to IN cord-022526-j9kg00qf 3486 10 reactive reactive JJ cord-022526-j9kg00qf 3486 11 oxygen oxygen NN cord-022526-j9kg00qf 3486 12 and and CC cord-022526-j9kg00qf 3486 13 nitrogen nitrogen NN cord-022526-j9kg00qf 3486 14 metabolites metabolite NNS cord-022526-j9kg00qf 3486 15 , , , cord-022526-j9kg00qf 3486 16 perhaps perhaps RB cord-022526-j9kg00qf 3486 17 the the DT cord-022526-j9kg00qf 3486 18 most most RBS cord-022526-j9kg00qf 3486 19 lethal lethal JJ cord-022526-j9kg00qf 3486 20 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 3486 21 mechanisms mechanism NNS cord-022526-j9kg00qf 3486 22 of of IN cord-022526-j9kg00qf 3486 23 macrophages macrophage NNS cord-022526-j9kg00qf 3486 24 . . . cord-022526-j9kg00qf 3487 1 30 30 CD cord-022526-j9kg00qf 3487 2 Diarrhea diarrhea NN cord-022526-j9kg00qf 3487 3 associated associate VBN cord-022526-j9kg00qf 3487 4 with with IN cord-022526-j9kg00qf 3487 5 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3487 6 has have VBZ cord-022526-j9kg00qf 3487 7 multiple multiple JJ cord-022526-j9kg00qf 3487 8 causes cause NNS cord-022526-j9kg00qf 3487 9 . . . cord-022526-j9kg00qf 3488 1 A a DT cord-022526-j9kg00qf 3488 2 Salmonella Salmonella NNP cord-022526-j9kg00qf 3488 3 cytotoxin cytotoxin NN cord-022526-j9kg00qf 3488 4 inhibits inhibit VBZ cord-022526-j9kg00qf 3488 5 protein protein NN cord-022526-j9kg00qf 3488 6 synthesis synthesis NN cord-022526-j9kg00qf 3488 7 in in IN cord-022526-j9kg00qf 3488 8 mucosal mucosal JJ cord-022526-j9kg00qf 3488 9 cells cell NNS cord-022526-j9kg00qf 3488 10 , , , cord-022526-j9kg00qf 3488 11 causing cause VBG cord-022526-j9kg00qf 3488 12 morphologic morphologic JJ cord-022526-j9kg00qf 3488 13 damage damage NN cord-022526-j9kg00qf 3488 14 and and CC cord-022526-j9kg00qf 3488 15 altered alter VBN cord-022526-j9kg00qf 3488 16 permeability permeability NN cord-022526-j9kg00qf 3488 17 . . . cord-022526-j9kg00qf 3489 1 31 31 CD cord-022526-j9kg00qf 3489 2 Virulent virulent JJ cord-022526-j9kg00qf 3489 3 salmonellae salmonella NNS cord-022526-j9kg00qf 3489 4 also also RB cord-022526-j9kg00qf 3489 5 produce produce VBP cord-022526-j9kg00qf 3489 6 an an DT cord-022526-j9kg00qf 3489 7 enterotoxin enterotoxin NN cord-022526-j9kg00qf 3489 8 similar similar JJ cord-022526-j9kg00qf 3489 9 to to IN cord-022526-j9kg00qf 3489 10 the the DT cord-022526-j9kg00qf 3489 11 heat heat NN cord-022526-j9kg00qf 3489 12 - - HYPH cord-022526-j9kg00qf 3489 13 labile labile JJ cord-022526-j9kg00qf 3489 14 toxin toxin NN cord-022526-j9kg00qf 3489 15 ( ( -LRB- cord-022526-j9kg00qf 3489 16 LT LT NNP cord-022526-j9kg00qf 3489 17 ) ) -RRB- cord-022526-j9kg00qf 3489 18 produced produce VBN cord-022526-j9kg00qf 3489 19 by by IN cord-022526-j9kg00qf 3489 20 Escherichia Escherichia NNP cord-022526-j9kg00qf 3489 21 coli coli NNS cord-022526-j9kg00qf 3489 22 . . . cord-022526-j9kg00qf 3490 1 32 32 CD cord-022526-j9kg00qf 3490 2 , , , cord-022526-j9kg00qf 3490 3 33 33 CD cord-022526-j9kg00qf 3491 1 The the DT cord-022526-j9kg00qf 3491 2 enterotoxin enterotoxin NN cord-022526-j9kg00qf 3491 3 contributes contribute VBZ cord-022526-j9kg00qf 3491 4 to to IN cord-022526-j9kg00qf 3491 5 but but CC cord-022526-j9kg00qf 3491 6 is be VBZ cord-022526-j9kg00qf 3491 7 not not RB cord-022526-j9kg00qf 3491 8 required require VBN cord-022526-j9kg00qf 3491 9 in in IN cord-022526-j9kg00qf 3491 10 the the DT cord-022526-j9kg00qf 3491 11 pathogenesis pathogenesis NN cord-022526-j9kg00qf 3491 12 of of IN cord-022526-j9kg00qf 3491 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3491 14 . . . cord-022526-j9kg00qf 3492 1 34 34 CD cord-022526-j9kg00qf 3492 2 , , , cord-022526-j9kg00qf 3492 3 35 35 CD cord-022526-j9kg00qf 3492 4 Salmonella salmonella NN cord-022526-j9kg00qf 3492 5 enterotoxin enterotoxin NN cord-022526-j9kg00qf 3492 6 increases increase VBZ cord-022526-j9kg00qf 3492 7 secretion secretion NN cord-022526-j9kg00qf 3492 8 of of IN cord-022526-j9kg00qf 3492 9 chloride chloride NN cord-022526-j9kg00qf 3492 10 and and CC cord-022526-j9kg00qf 3492 11 water water NN cord-022526-j9kg00qf 3492 12 by by IN cord-022526-j9kg00qf 3492 13 colonic colonic JJ cord-022526-j9kg00qf 3492 14 mucosal mucosal JJ cord-022526-j9kg00qf 3492 15 cells cell NNS cord-022526-j9kg00qf 3492 16 in in IN cord-022526-j9kg00qf 3492 17 many many JJ cord-022526-j9kg00qf 3492 18 species specie NNS cord-022526-j9kg00qf 3492 19 , , , cord-022526-j9kg00qf 3492 20 including include VBG cord-022526-j9kg00qf 3492 21 horses horse NNS cord-022526-j9kg00qf 3492 22 , , , cord-022526-j9kg00qf 3492 23 by by IN cord-022526-j9kg00qf 3492 24 increasing increase VBG cord-022526-j9kg00qf 3492 25 intracellular intracellular JJ cord-022526-j9kg00qf 3492 26 cyclic cyclic JJ cord-022526-j9kg00qf 3492 27 adenosine adenosine NN cord-022526-j9kg00qf 3492 28 monophosphate monophosphate NN cord-022526-j9kg00qf 3492 29 concentrations concentration NNS cord-022526-j9kg00qf 3492 30 . . . cord-022526-j9kg00qf 3493 1 The the DT cord-022526-j9kg00qf 3493 2 ability ability NN cord-022526-j9kg00qf 3493 3 of of IN cord-022526-j9kg00qf 3493 4 virulent virulent JJ cord-022526-j9kg00qf 3493 5 salmonellae salmonella NNS cord-022526-j9kg00qf 3493 6 to to TO cord-022526-j9kg00qf 3493 7 cause cause VB cord-022526-j9kg00qf 3493 8 diarrhea diarrhea NN cord-022526-j9kg00qf 3493 9 appears appear VBZ cord-022526-j9kg00qf 3493 10 to to TO cord-022526-j9kg00qf 3493 11 be be VB cord-022526-j9kg00qf 3493 12 associated associate VBN cord-022526-j9kg00qf 3493 13 most most RBS cord-022526-j9kg00qf 3493 14 closely closely RB cord-022526-j9kg00qf 3493 15 with with IN cord-022526-j9kg00qf 3493 16 the the DT cord-022526-j9kg00qf 3493 17 ability ability NN cord-022526-j9kg00qf 3493 18 to to TO cord-022526-j9kg00qf 3493 19 invade invade VB cord-022526-j9kg00qf 3493 20 enterocytes enterocyte NNS cord-022526-j9kg00qf 3493 21 and and CC cord-022526-j9kg00qf 3493 22 to to TO cord-022526-j9kg00qf 3493 23 trigger trigger VB cord-022526-j9kg00qf 3493 24 an an DT cord-022526-j9kg00qf 3493 25 inflammatory inflammatory JJ cord-022526-j9kg00qf 3493 26 reaction reaction NN cord-022526-j9kg00qf 3493 27 in in IN cord-022526-j9kg00qf 3493 28 the the DT cord-022526-j9kg00qf 3493 29 intestinal intestinal JJ cord-022526-j9kg00qf 3493 30 tissue tissue NN cord-022526-j9kg00qf 3493 31 . . . cord-022526-j9kg00qf 3494 1 20 20 CD cord-022526-j9kg00qf 3494 2 , , , cord-022526-j9kg00qf 3494 3 36 36 CD cord-022526-j9kg00qf 3494 4 Gene Gene NNP cord-022526-j9kg00qf 3494 5 products product NNS cord-022526-j9kg00qf 3494 6 injected inject VBN cord-022526-j9kg00qf 3494 7 into into IN cord-022526-j9kg00qf 3494 8 enterocyte enterocyte NNP cord-022526-j9kg00qf 3494 9 cytosol cytosol NN cord-022526-j9kg00qf 3494 10 by by IN cord-022526-j9kg00qf 3494 11 the the DT cord-022526-j9kg00qf 3494 12 type type NN cord-022526-j9kg00qf 3494 13 III iii CD cord-022526-j9kg00qf 3494 14 secretory secretory NN cord-022526-j9kg00qf 3494 15 system system NN cord-022526-j9kg00qf 3494 16 of of IN cord-022526-j9kg00qf 3494 17 invading invade VBG cord-022526-j9kg00qf 3494 18 salmonellae salmonellae NNP cord-022526-j9kg00qf 3494 19 stimulate stimulate VBP cord-022526-j9kg00qf 3494 20 chloride chloride NN cord-022526-j9kg00qf 3494 21 and and CC cord-022526-j9kg00qf 3494 22 fluid fluid JJ cord-022526-j9kg00qf 3494 23 secretion secretion NN cord-022526-j9kg00qf 3494 24 . . . cord-022526-j9kg00qf 3495 1 27 27 CD cord-022526-j9kg00qf 3495 2 Salmonella Salmonella NNP cord-022526-j9kg00qf 3495 3 invasion invasion NN cord-022526-j9kg00qf 3495 4 of of IN cord-022526-j9kg00qf 3495 5 enterocytes enterocytes NNP cord-022526-j9kg00qf 3495 6 is be VBZ cord-022526-j9kg00qf 3495 7 also also RB cord-022526-j9kg00qf 3495 8 a a DT cord-022526-j9kg00qf 3495 9 potent potent JJ cord-022526-j9kg00qf 3495 10 activator activator NN cord-022526-j9kg00qf 3495 11 of of IN cord-022526-j9kg00qf 3495 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 3495 13 chemokine chemokine NN cord-022526-j9kg00qf 3495 14 and and CC cord-022526-j9kg00qf 3495 15 cytokine cytokine NN cord-022526-j9kg00qf 3495 16 production production NN cord-022526-j9kg00qf 3495 17 , , , cord-022526-j9kg00qf 3495 18 resulting result VBG cord-022526-j9kg00qf 3495 19 in in IN cord-022526-j9kg00qf 3495 20 the the DT cord-022526-j9kg00qf 3495 21 recruitment recruitment NN cord-022526-j9kg00qf 3495 22 of of IN cord-022526-j9kg00qf 3495 23 leukocytes leukocyte NNS cord-022526-j9kg00qf 3495 24 , , , cord-022526-j9kg00qf 3495 25 particularly particularly RB cord-022526-j9kg00qf 3495 26 neutrophils neutrophil NNS cord-022526-j9kg00qf 3495 27 , , , cord-022526-j9kg00qf 3495 28 and and CC cord-022526-j9kg00qf 3495 29 activation activation NN cord-022526-j9kg00qf 3495 30 of of IN cord-022526-j9kg00qf 3495 31 resident resident JJ cord-022526-j9kg00qf 3495 32 macrophages macrophage NNS cord-022526-j9kg00qf 3495 33 and and CC cord-022526-j9kg00qf 3495 34 mast mast NN cord-022526-j9kg00qf 3495 35 cells cell NNS cord-022526-j9kg00qf 3495 36 . . . cord-022526-j9kg00qf 3496 1 Products product NNS cord-022526-j9kg00qf 3496 2 of of IN cord-022526-j9kg00qf 3496 3 these these DT cord-022526-j9kg00qf 3496 4 activated activate VBN cord-022526-j9kg00qf 3496 5 leukocytes leukocyte NNS cord-022526-j9kg00qf 3496 6 , , , cord-022526-j9kg00qf 3496 7 including include VBG cord-022526-j9kg00qf 3496 8 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 3496 9 , , , cord-022526-j9kg00qf 3496 10 leukotrienes leukotriene NNS cord-022526-j9kg00qf 3496 11 , , , cord-022526-j9kg00qf 3496 12 reactive reactive JJ cord-022526-j9kg00qf 3496 13 oxygen oxygen NN cord-022526-j9kg00qf 3496 14 metabolites metabolite NNS cord-022526-j9kg00qf 3496 15 , , , cord-022526-j9kg00qf 3496 16 and and CC cord-022526-j9kg00qf 3496 17 histamine histamine NN cord-022526-j9kg00qf 3496 18 , , , cord-022526-j9kg00qf 3496 19 are be VBP cord-022526-j9kg00qf 3496 20 potent potent JJ cord-022526-j9kg00qf 3496 21 stimulators stimulator NNS cord-022526-j9kg00qf 3496 22 of of IN cord-022526-j9kg00qf 3496 23 chloride chloride NN cord-022526-j9kg00qf 3496 24 secretion secretion NN cord-022526-j9kg00qf 3496 25 in in IN cord-022526-j9kg00qf 3496 26 the the DT cord-022526-j9kg00qf 3496 27 colon colon NN cord-022526-j9kg00qf 3496 28 of of IN cord-022526-j9kg00qf 3496 29 many many JJ cord-022526-j9kg00qf 3496 30 species specie NNS cord-022526-j9kg00qf 3496 31 . . . cord-022526-j9kg00qf 3497 1 16 16 CD cord-022526-j9kg00qf 3497 2 , , , cord-022526-j9kg00qf 3497 3 [ [ -LRB- cord-022526-j9kg00qf 3497 4 37 37 CD cord-022526-j9kg00qf 3497 5 ] ] -RRB- cord-022526-j9kg00qf 3497 6 [ [ -LRB- cord-022526-j9kg00qf 3497 7 38 38 CD cord-022526-j9kg00qf 3497 8 ] ] -RRB- cord-022526-j9kg00qf 3498 1 [ [ -LRB- cord-022526-j9kg00qf 3498 2 39 39 CD cord-022526-j9kg00qf 3498 3 ] ] -RRB- cord-022526-j9kg00qf 3499 1 The the DT cord-022526-j9kg00qf 3499 2 enteric enteric JJ cord-022526-j9kg00qf 3499 3 nervous nervous JJ cord-022526-j9kg00qf 3499 4 system system NN cord-022526-j9kg00qf 3499 5 integrates integrate VBZ cord-022526-j9kg00qf 3499 6 the the DT cord-022526-j9kg00qf 3499 7 diverse diverse JJ cord-022526-j9kg00qf 3499 8 processes process NNS cord-022526-j9kg00qf 3499 9 of of IN cord-022526-j9kg00qf 3499 10 pathogen pathogen NN cord-022526-j9kg00qf 3499 11 recognition recognition NN cord-022526-j9kg00qf 3499 12 , , , cord-022526-j9kg00qf 3499 13 triggering trigger VBG cord-022526-j9kg00qf 3499 14 of of IN cord-022526-j9kg00qf 3499 15 the the DT cord-022526-j9kg00qf 3499 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 3499 17 response response NN cord-022526-j9kg00qf 3499 18 , , , cord-022526-j9kg00qf 3499 19 and and CC cord-022526-j9kg00qf 3499 20 induction induction NN cord-022526-j9kg00qf 3499 21 of of IN cord-022526-j9kg00qf 3499 22 enterocyte enterocyte NNP cord-022526-j9kg00qf 3499 23 fluid fluid JJ cord-022526-j9kg00qf 3499 24 secretion secretion NN cord-022526-j9kg00qf 3499 25 . . . cord-022526-j9kg00qf 3500 1 39 39 CD cord-022526-j9kg00qf 3500 2 Many many JJ cord-022526-j9kg00qf 3500 3 of of IN cord-022526-j9kg00qf 3500 4 the the DT cord-022526-j9kg00qf 3500 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 3500 6 mediators mediator NNS cord-022526-j9kg00qf 3500 7 studied study VBD cord-022526-j9kg00qf 3500 8 stimulate stimulate VBP cord-022526-j9kg00qf 3500 9 colonic colonic JJ cord-022526-j9kg00qf 3500 10 secretion secretion NN cord-022526-j9kg00qf 3500 11 by by IN cord-022526-j9kg00qf 3500 12 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3500 13 - - HYPH cord-022526-j9kg00qf 3500 14 dependent dependent JJ cord-022526-j9kg00qf 3500 15 mechanisms mechanism NNS cord-022526-j9kg00qf 3500 16 , , , cord-022526-j9kg00qf 3500 17 resulting result VBG cord-022526-j9kg00qf 3500 18 in in IN cord-022526-j9kg00qf 3500 19 increased increase VBN cord-022526-j9kg00qf 3500 20 intracellular intracellular JJ cord-022526-j9kg00qf 3500 21 cyclic cyclic JJ cord-022526-j9kg00qf 3500 22 adenosine adenosine NN cord-022526-j9kg00qf 3500 23 monophosphate monophosphate NN cord-022526-j9kg00qf 3500 24 or or CC cord-022526-j9kg00qf 3500 25 calcium calcium NN cord-022526-j9kg00qf 3500 26 concentrations concentration NNS cord-022526-j9kg00qf 3500 27 or or CC cord-022526-j9kg00qf 3500 28 both both DT cord-022526-j9kg00qf 3500 29 in in IN cord-022526-j9kg00qf 3500 30 mucosal mucosal JJ cord-022526-j9kg00qf 3500 31 cells cell NNS cord-022526-j9kg00qf 3500 32 . . . cord-022526-j9kg00qf 3501 1 37 37 CD cord-022526-j9kg00qf 3502 1 In in IN cord-022526-j9kg00qf 3502 2 addition addition NN cord-022526-j9kg00qf 3502 3 , , , cord-022526-j9kg00qf 3502 4 these these DT cord-022526-j9kg00qf 3502 5 mediators mediator NNS cord-022526-j9kg00qf 3502 6 and and CC cord-022526-j9kg00qf 3502 7 the the DT cord-022526-j9kg00qf 3502 8 enteric enteric JJ cord-022526-j9kg00qf 3502 9 nervous nervous JJ cord-022526-j9kg00qf 3502 10 system system NN cord-022526-j9kg00qf 3502 11 may may MD cord-022526-j9kg00qf 3502 12 stimulate stimulate VB cord-022526-j9kg00qf 3502 13 secretion secretion NN cord-022526-j9kg00qf 3502 14 by by IN cord-022526-j9kg00qf 3502 15 prostaglandin prostaglandin NN cord-022526-j9kg00qf 3502 16 - - HYPH cord-022526-j9kg00qf 3502 17 independent independent JJ cord-022526-j9kg00qf 3502 18 mechanisms mechanism NNS cord-022526-j9kg00qf 3502 19 , , , cord-022526-j9kg00qf 3502 20 inhibit inhibit VBP cord-022526-j9kg00qf 3502 21 sodium sodium NN cord-022526-j9kg00qf 3502 22 and and CC cord-022526-j9kg00qf 3502 23 water water NN cord-022526-j9kg00qf 3502 24 absorption absorption NN cord-022526-j9kg00qf 3502 25 , , , cord-022526-j9kg00qf 3502 26 cause cause VB cord-022526-j9kg00qf 3502 27 motility motility NN cord-022526-j9kg00qf 3502 28 disturbances disturbance NNS cord-022526-j9kg00qf 3502 29 , , , cord-022526-j9kg00qf 3502 30 and and CC cord-022526-j9kg00qf 3502 31 potentiate potentiate VBP cord-022526-j9kg00qf 3502 32 tissue tissue NN cord-022526-j9kg00qf 3502 33 injury injury NN cord-022526-j9kg00qf 3502 34 , , , cord-022526-j9kg00qf 3502 35 all all DT cord-022526-j9kg00qf 3502 36 of of IN cord-022526-j9kg00qf 3502 37 which which WDT cord-022526-j9kg00qf 3502 38 enhance enhance VBP cord-022526-j9kg00qf 3502 39 the the DT cord-022526-j9kg00qf 3502 40 pathogenicity pathogenicity NN cord-022526-j9kg00qf 3502 41 and and CC cord-022526-j9kg00qf 3502 42 dissemination dissemination NN cord-022526-j9kg00qf 3502 43 of of IN cord-022526-j9kg00qf 3502 44 Salmonella Salmonella NNP cord-022526-j9kg00qf 3502 45 and and CC cord-022526-j9kg00qf 3502 46 contribute contribute VB cord-022526-j9kg00qf 3502 47 to to IN cord-022526-j9kg00qf 3502 48 the the DT cord-022526-j9kg00qf 3502 49 pathogenesis pathogenesis NN cord-022526-j9kg00qf 3502 50 of of IN cord-022526-j9kg00qf 3502 51 diarrhea diarrhea NN cord-022526-j9kg00qf 3502 52 . . . cord-022526-j9kg00qf 3503 1 37 37 CD cord-022526-j9kg00qf 3503 2 , , , cord-022526-j9kg00qf 3503 3 39 39 CD cord-022526-j9kg00qf 3503 4 Neutrophils neutrophil NNS cord-022526-j9kg00qf 3503 5 recruited recruit VBN cord-022526-j9kg00qf 3503 6 to to IN cord-022526-j9kg00qf 3503 7 the the DT cord-022526-j9kg00qf 3503 8 mucosa mucosa NN cord-022526-j9kg00qf 3503 9 by by IN cord-022526-j9kg00qf 3503 10 signals signal NNS cord-022526-j9kg00qf 3503 11 generated generate VBN cord-022526-j9kg00qf 3503 12 by by IN cord-022526-j9kg00qf 3503 13 the the DT cord-022526-j9kg00qf 3503 14 infected infected JJ cord-022526-j9kg00qf 3503 15 enterocytes enterocyte NNS cord-022526-j9kg00qf 3503 16 physically physically RB cord-022526-j9kg00qf 3503 17 contribute contribute VBP cord-022526-j9kg00qf 3503 18 to to IN cord-022526-j9kg00qf 3503 19 mucosal mucosal JJ cord-022526-j9kg00qf 3503 20 injury injury NN cord-022526-j9kg00qf 3503 21 by by IN cord-022526-j9kg00qf 3503 22 producing produce VBG cord-022526-j9kg00qf 3503 23 a a DT cord-022526-j9kg00qf 3503 24 variety variety NN cord-022526-j9kg00qf 3503 25 of of IN cord-022526-j9kg00qf 3503 26 products product NNS cord-022526-j9kg00qf 3503 27 that that WDT cord-022526-j9kg00qf 3503 28 are be VBP cord-022526-j9kg00qf 3503 29 lethal lethal JJ cord-022526-j9kg00qf 3503 30 to to IN cord-022526-j9kg00qf 3503 31 pathogens pathogen NNS cord-022526-j9kg00qf 3503 32 but but CC cord-022526-j9kg00qf 3503 33 are be VBP cord-022526-j9kg00qf 3503 34 also also RB cord-022526-j9kg00qf 3503 35 toxic toxic JJ cord-022526-j9kg00qf 3503 36 to to TO cord-022526-j9kg00qf 3503 37 host host VB cord-022526-j9kg00qf 3503 38 cells cell NNS cord-022526-j9kg00qf 3503 39 . . . cord-022526-j9kg00qf 3504 1 40 40 CD cord-022526-j9kg00qf 3504 2 , , , cord-022526-j9kg00qf 3504 3 41 41 CD cord-022526-j9kg00qf 3504 4 Moreover moreover RB cord-022526-j9kg00qf 3504 5 , , , cord-022526-j9kg00qf 3504 6 neutrophils neutrophil NNS cord-022526-j9kg00qf 3504 7 attracted attract VBD cord-022526-j9kg00qf 3504 8 to to IN cord-022526-j9kg00qf 3504 9 infected infected JJ cord-022526-j9kg00qf 3504 10 epithelial epithelial JJ cord-022526-j9kg00qf 3504 11 cells cell NNS cord-022526-j9kg00qf 3504 12 accumulate accumulate VBP cord-022526-j9kg00qf 3504 13 beneath beneath IN cord-022526-j9kg00qf 3504 14 the the DT cord-022526-j9kg00qf 3504 15 monolayer monolayer NN cord-022526-j9kg00qf 3504 16 , , , cord-022526-j9kg00qf 3504 17 lifting lift VBG cord-022526-j9kg00qf 3504 18 it -PRON- PRP cord-022526-j9kg00qf 3504 19 off off IN cord-022526-j9kg00qf 3504 20 the the DT cord-022526-j9kg00qf 3504 21 basement basement NN cord-022526-j9kg00qf 3504 22 membrane membrane NN cord-022526-j9kg00qf 3504 23 in in IN cord-022526-j9kg00qf 3504 24 sheets sheet NNS cord-022526-j9kg00qf 3504 25 . . . cord-022526-j9kg00qf 3505 1 Neutrophils neutrophils NN cord-022526-j9kg00qf 3505 2 also also RB cord-022526-j9kg00qf 3505 3 migrate migrate VBP cord-022526-j9kg00qf 3505 4 across across IN cord-022526-j9kg00qf 3505 5 the the DT cord-022526-j9kg00qf 3505 6 epithelial epithelial JJ cord-022526-j9kg00qf 3505 7 monolayer monolayer NN cord-022526-j9kg00qf 3505 8 in in IN cord-022526-j9kg00qf 3505 9 potentially potentially RB cord-022526-j9kg00qf 3505 10 massive massive JJ cord-022526-j9kg00qf 3505 11 numbers number NNS cord-022526-j9kg00qf 3505 12 . . . cord-022526-j9kg00qf 3506 1 Transepithelial transepithelial JJ cord-022526-j9kg00qf 3506 2 migration migration NN cord-022526-j9kg00qf 3506 3 of of IN cord-022526-j9kg00qf 3506 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 3506 5 increases increase VBZ cord-022526-j9kg00qf 3506 6 the the DT cord-022526-j9kg00qf 3506 7 permeability permeability NN cord-022526-j9kg00qf 3506 8 to to IN cord-022526-j9kg00qf 3506 9 macromolecules macromolecule NNS cord-022526-j9kg00qf 3506 10 , , , cord-022526-j9kg00qf 3506 11 bacterial bacterial JJ cord-022526-j9kg00qf 3506 12 products product NNS cord-022526-j9kg00qf 3506 13 , , , cord-022526-j9kg00qf 3506 14 and and CC cord-022526-j9kg00qf 3506 15 even even RB cord-022526-j9kg00qf 3506 16 bacteria bacteria NNS cord-022526-j9kg00qf 3506 17 . . . cord-022526-j9kg00qf 3507 1 41 41 CD cord-022526-j9kg00qf 3508 1 Potentially potentially RB cord-022526-j9kg00qf 3508 2 massive massive JJ cord-022526-j9kg00qf 3508 3 losses loss NNS cord-022526-j9kg00qf 3508 4 of of IN cord-022526-j9kg00qf 3508 5 electrolytes electrolyte NNS cord-022526-j9kg00qf 3508 6 , , , cord-022526-j9kg00qf 3508 7 water water NN cord-022526-j9kg00qf 3508 8 , , , cord-022526-j9kg00qf 3508 9 and and CC cord-022526-j9kg00qf 3508 10 protein protein NN cord-022526-j9kg00qf 3508 11 can can MD cord-022526-j9kg00qf 3508 12 occur occur VB cord-022526-j9kg00qf 3508 13 depending depend VBG cord-022526-j9kg00qf 3508 14 on on IN cord-022526-j9kg00qf 3508 15 bacterial bacterial JJ cord-022526-j9kg00qf 3508 16 and and CC cord-022526-j9kg00qf 3508 17 host host NN cord-022526-j9kg00qf 3508 18 factors factor NNS cord-022526-j9kg00qf 3508 19 . . . cord-022526-j9kg00qf 3509 1 Perhaps perhaps RB cord-022526-j9kg00qf 3509 2 most most RBS cord-022526-j9kg00qf 3509 3 devastatingly devastatingly RB cord-022526-j9kg00qf 3509 4 , , , cord-022526-j9kg00qf 3509 5 mucosal mucosal JJ cord-022526-j9kg00qf 3509 6 injury injury NN cord-022526-j9kg00qf 3509 7 and and CC cord-022526-j9kg00qf 3509 8 altered alter VBN cord-022526-j9kg00qf 3509 9 permeability permeability NN cord-022526-j9kg00qf 3509 10 allow allow VBP cord-022526-j9kg00qf 3509 11 systemic systemic JJ cord-022526-j9kg00qf 3509 12 absorption absorption NN cord-022526-j9kg00qf 3509 13 of of IN cord-022526-j9kg00qf 3509 14 bacterial bacterial JJ cord-022526-j9kg00qf 3509 15 products product NNS cord-022526-j9kg00qf 3509 16 and and CC cord-022526-j9kg00qf 3509 17 dissemination dissemination NN cord-022526-j9kg00qf 3509 18 of of IN cord-022526-j9kg00qf 3509 19 bacteria bacteria NNS cord-022526-j9kg00qf 3509 20 , , , cord-022526-j9kg00qf 3509 21 resulting result VBG cord-022526-j9kg00qf 3509 22 in in IN cord-022526-j9kg00qf 3509 23 systemic systemic JJ cord-022526-j9kg00qf 3509 24 inflammatory inflammatory JJ cord-022526-j9kg00qf 3509 25 responses response NNS cord-022526-j9kg00qf 3509 26 such such JJ cord-022526-j9kg00qf 3509 27 as as IN cord-022526-j9kg00qf 3509 28 occur occur VBP cord-022526-j9kg00qf 3509 29 with with IN cord-022526-j9kg00qf 3509 30 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3509 31 and and CC cord-022526-j9kg00qf 3509 32 septicemia septicemia NN cord-022526-j9kg00qf 3509 33 . . . cord-022526-j9kg00qf 3510 1 Four four CD cord-022526-j9kg00qf 3510 2 syndromes syndrome NNS cord-022526-j9kg00qf 3510 3 of of IN cord-022526-j9kg00qf 3510 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 3510 5 infection infection NN cord-022526-j9kg00qf 3510 6 have have VBP cord-022526-j9kg00qf 3510 7 been be VBN cord-022526-j9kg00qf 3510 8 described describe VBN cord-022526-j9kg00qf 3510 9 clinically clinically RB cord-022526-j9kg00qf 3510 10 and and CC cord-022526-j9kg00qf 3510 11 reproduced reproduce VBN cord-022526-j9kg00qf 3510 12 experimentally experimentally RB cord-022526-j9kg00qf 3510 13 in in IN cord-022526-j9kg00qf 3510 14 horses horse NNS cord-022526-j9kg00qf 3510 15 : : : cord-022526-j9kg00qf 3510 16 ( ( -LRB- cord-022526-j9kg00qf 3510 17 1 1 LS cord-022526-j9kg00qf 3510 18 ) ) -RRB- cord-022526-j9kg00qf 3510 19 inapparent inapparent JJ cord-022526-j9kg00qf 3510 20 infections infection NNS cord-022526-j9kg00qf 3510 21 with with IN cord-022526-j9kg00qf 3510 22 latent latent JJ cord-022526-j9kg00qf 3510 23 or or CC cord-022526-j9kg00qf 3510 24 active active JJ cord-022526-j9kg00qf 3510 25 carrier carrier NN cord-022526-j9kg00qf 3510 26 states state NNS cord-022526-j9kg00qf 3510 27 ; ; , cord-022526-j9kg00qf 3510 28 ( ( -LRB- cord-022526-j9kg00qf 3510 29 2 2 LS cord-022526-j9kg00qf 3510 30 ) ) -RRB- cord-022526-j9kg00qf 3510 31 depression depression NN cord-022526-j9kg00qf 3510 32 , , , cord-022526-j9kg00qf 3510 33 fever fever NN cord-022526-j9kg00qf 3510 34 , , , cord-022526-j9kg00qf 3510 35 anorexia anorexia NN cord-022526-j9kg00qf 3510 36 , , , cord-022526-j9kg00qf 3510 37 and and CC cord-022526-j9kg00qf 3510 38 neutropenia neutropenia NN cord-022526-j9kg00qf 3510 39 without without IN cord-022526-j9kg00qf 3510 40 diarrhea diarrhea NN cord-022526-j9kg00qf 3510 41 or or CC cord-022526-j9kg00qf 3510 42 colic colic NN cord-022526-j9kg00qf 3510 43 ; ; : cord-022526-j9kg00qf 3510 44 ( ( -LRB- cord-022526-j9kg00qf 3510 45 3 3 LS cord-022526-j9kg00qf 3510 46 ) ) -RRB- cord-022526-j9kg00qf 3510 47 fulminant fulminant JJ cord-022526-j9kg00qf 3510 48 or or CC cord-022526-j9kg00qf 3510 49 peracute peracute JJ cord-022526-j9kg00qf 3510 50 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3510 51 with with IN cord-022526-j9kg00qf 3510 52 diarrhea diarrhea NN cord-022526-j9kg00qf 3510 53 ; ; : cord-022526-j9kg00qf 3510 54 and and CC cord-022526-j9kg00qf 3510 55 ( ( -LRB- cord-022526-j9kg00qf 3510 56 4 4 LS cord-022526-j9kg00qf 3510 57 ) ) -RRB- cord-022526-j9kg00qf 3510 58 septicemia septicemia NN cord-022526-j9kg00qf 3510 59 ( ( -LRB- cord-022526-j9kg00qf 3510 60 enteric enteric JJ cord-022526-j9kg00qf 3510 61 fever fever NN cord-022526-j9kg00qf 3510 62 ) ) -RRB- cord-022526-j9kg00qf 3510 63 with with IN cord-022526-j9kg00qf 3510 64 or or CC cord-022526-j9kg00qf 3510 65 without without IN cord-022526-j9kg00qf 3510 66 diarrhea diarrhea NN cord-022526-j9kg00qf 3510 67 . . . cord-022526-j9kg00qf 3511 1 Inapparent inapparent JJ cord-022526-j9kg00qf 3511 2 infections infection NNS cord-022526-j9kg00qf 3511 3 can can MD cord-022526-j9kg00qf 3511 4 be be VB cord-022526-j9kg00qf 3511 5 activated activate VBN cord-022526-j9kg00qf 3511 6 to to IN cord-022526-j9kg00qf 3511 7 clinical clinical JJ cord-022526-j9kg00qf 3511 8 disease disease NN cord-022526-j9kg00qf 3511 9 in in IN cord-022526-j9kg00qf 3511 10 compromised compromise VBN cord-022526-j9kg00qf 3511 11 horses horse NNS cord-022526-j9kg00qf 3511 12 , , , cord-022526-j9kg00qf 3511 13 such such JJ cord-022526-j9kg00qf 3511 14 as as IN cord-022526-j9kg00qf 3511 15 horses horse NNS cord-022526-j9kg00qf 3511 16 with with IN cord-022526-j9kg00qf 3511 17 colic colic NN cord-022526-j9kg00qf 3511 18 or or CC cord-022526-j9kg00qf 3511 19 horses horse NNS cord-022526-j9kg00qf 3511 20 being be VBG cord-022526-j9kg00qf 3511 21 treated treat VBN cord-022526-j9kg00qf 3511 22 with with IN cord-022526-j9kg00qf 3511 23 antibiotics antibiotic NNS cord-022526-j9kg00qf 3511 24 , , , cord-022526-j9kg00qf 3511 25 causing cause VBG cord-022526-j9kg00qf 3511 26 mild mild JJ cord-022526-j9kg00qf 3511 27 to to IN cord-022526-j9kg00qf 3511 28 severe severe JJ cord-022526-j9kg00qf 3511 29 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3511 30 . . . cord-022526-j9kg00qf 3512 1 In in IN cord-022526-j9kg00qf 3512 2 addition addition NN cord-022526-j9kg00qf 3512 3 , , , cord-022526-j9kg00qf 3512 4 latent latent JJ cord-022526-j9kg00qf 3512 5 infections infection NNS cord-022526-j9kg00qf 3512 6 ( ( -LRB- cord-022526-j9kg00qf 3512 7 nonshedding nonshedding NN cord-022526-j9kg00qf 3512 8 ) ) -RRB- cord-022526-j9kg00qf 3512 9 can can MD cord-022526-j9kg00qf 3512 10 become become VB cord-022526-j9kg00qf 3512 11 active active JJ cord-022526-j9kg00qf 3512 12 infections infection NNS cord-022526-j9kg00qf 3512 13 ( ( -LRB- cord-022526-j9kg00qf 3512 14 shedding shed VBG cord-022526-j9kg00qf 3512 15 ) ) -RRB- cord-022526-j9kg00qf 3512 16 under under IN cord-022526-j9kg00qf 3512 17 certain certain JJ cord-022526-j9kg00qf 3512 18 conditions condition NNS cord-022526-j9kg00qf 3512 19 , , , cord-022526-j9kg00qf 3512 20 such such JJ cord-022526-j9kg00qf 3512 21 as as IN cord-022526-j9kg00qf 3512 22 transportation transportation NN cord-022526-j9kg00qf 3512 23 stress stress NN cord-022526-j9kg00qf 3512 24 and and CC cord-022526-j9kg00qf 3512 25 antibiotic antibiotic JJ cord-022526-j9kg00qf 3512 26 treatment treatment NN cord-022526-j9kg00qf 3512 27 . . . cord-022526-j9kg00qf 3513 1 Horses horse NNS cord-022526-j9kg00qf 3513 2 with with IN cord-022526-j9kg00qf 3513 3 depression depression NN cord-022526-j9kg00qf 3513 4 , , , cord-022526-j9kg00qf 3513 5 anorexia anorexia NN cord-022526-j9kg00qf 3513 6 , , , cord-022526-j9kg00qf 3513 7 fever fever NN cord-022526-j9kg00qf 3513 8 , , , cord-022526-j9kg00qf 3513 9 and and CC cord-022526-j9kg00qf 3513 10 neutropenia neutropenia NN cord-022526-j9kg00qf 3513 11 without without IN cord-022526-j9kg00qf 3513 12 diarrhea diarrhea NN cord-022526-j9kg00qf 3513 13 generally generally RB cord-022526-j9kg00qf 3513 14 have have VBP cord-022526-j9kg00qf 3513 15 a a DT cord-022526-j9kg00qf 3513 16 good good JJ cord-022526-j9kg00qf 3513 17 prognosis prognosis NN cord-022526-j9kg00qf 3513 18 and and CC cord-022526-j9kg00qf 3513 19 recover recover VB cord-022526-j9kg00qf 3513 20 in in IN cord-022526-j9kg00qf 3513 21 several several JJ cord-022526-j9kg00qf 3513 22 days day NNS cord-022526-j9kg00qf 3513 23 without without IN cord-022526-j9kg00qf 3513 24 specific specific JJ cord-022526-j9kg00qf 3513 25 treatment treatment NN cord-022526-j9kg00qf 3513 26 . . . cord-022526-j9kg00qf 3514 1 42 42 CD cord-022526-j9kg00qf 3515 1 The the DT cord-022526-j9kg00qf 3515 2 septicemic septicemic JJ cord-022526-j9kg00qf 3515 3 form form NN cord-022526-j9kg00qf 3515 4 is be VBZ cord-022526-j9kg00qf 3515 5 restricted restrict VBN cord-022526-j9kg00qf 3515 6 mostly mostly RB cord-022526-j9kg00qf 3515 7 to to IN cord-022526-j9kg00qf 3515 8 neonatal neonatal JJ cord-022526-j9kg00qf 3515 9 foals foal NNS cord-022526-j9kg00qf 3515 10 and and CC cord-022526-j9kg00qf 3515 11 is be VBZ cord-022526-j9kg00qf 3515 12 uncommon uncommon JJ cord-022526-j9kg00qf 3515 13 in in IN cord-022526-j9kg00qf 3515 14 adult adult NN cord-022526-j9kg00qf 3515 15 horses horse NNS cord-022526-j9kg00qf 3515 16 . . . cord-022526-j9kg00qf 3516 1 This this DT cord-022526-j9kg00qf 3516 2 discussion discussion NN cord-022526-j9kg00qf 3516 3 focuses focus VBZ cord-022526-j9kg00qf 3516 4 on on IN cord-022526-j9kg00qf 3516 5 acute acute JJ cord-022526-j9kg00qf 3516 6 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3516 7 . . . cord-022526-j9kg00qf 3517 1 Acute acute JJ cord-022526-j9kg00qf 3517 2 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3517 3 is be VBZ cord-022526-j9kg00qf 3517 4 characterized characterize VBN cord-022526-j9kg00qf 3517 5 by by IN cord-022526-j9kg00qf 3517 6 severe severe JJ cord-022526-j9kg00qf 3517 7 fibrinonecrotic fibrinonecrotic JJ cord-022526-j9kg00qf 3517 8 typhlocolitis typhlocolitis NN cord-022526-j9kg00qf 3517 9 , , , cord-022526-j9kg00qf 3517 10 with with IN cord-022526-j9kg00qf 3517 11 interstitial interstitial JJ cord-022526-j9kg00qf 3517 12 edema edema NN cord-022526-j9kg00qf 3517 13 and and CC cord-022526-j9kg00qf 3517 14 variable variable JJ cord-022526-j9kg00qf 3517 15 degrees degree NNS cord-022526-j9kg00qf 3517 16 of of IN cord-022526-j9kg00qf 3517 17 intramural intramural JJ cord-022526-j9kg00qf 3517 18 vascular vascular JJ cord-022526-j9kg00qf 3517 19 thrombosis thrombosis NN cord-022526-j9kg00qf 3517 20 that that WDT cord-022526-j9kg00qf 3517 21 may may MD cord-022526-j9kg00qf 3517 22 progress progress VB cord-022526-j9kg00qf 3517 23 to to IN cord-022526-j9kg00qf 3517 24 infarction infarction NN cord-022526-j9kg00qf 3517 25 . . . cord-022526-j9kg00qf 3518 1 1 1 LS cord-022526-j9kg00qf 3518 2 Severe severe JJ cord-022526-j9kg00qf 3518 3 ulceration ulceration NN cord-022526-j9kg00qf 3518 4 of of IN cord-022526-j9kg00qf 3518 5 the the DT cord-022526-j9kg00qf 3518 6 large large JJ cord-022526-j9kg00qf 3518 7 intestinal intestinal JJ cord-022526-j9kg00qf 3518 8 mucosa mucosa NN cord-022526-j9kg00qf 3518 9 may may MD cord-022526-j9kg00qf 3518 10 occur occur VB cord-022526-j9kg00qf 3518 11 with with IN cord-022526-j9kg00qf 3518 12 serosal serosal NN cord-022526-j9kg00qf 3518 13 ecchymoses ecchymosis NNS cord-022526-j9kg00qf 3518 14 and and CC cord-022526-j9kg00qf 3518 15 congestion congestion NN cord-022526-j9kg00qf 3518 16 . . . cord-022526-j9kg00qf 3519 1 The the DT cord-022526-j9kg00qf 3519 2 earliest early JJS cord-022526-j9kg00qf 3519 3 signs sign NNS cord-022526-j9kg00qf 3519 4 of of IN cord-022526-j9kg00qf 3519 5 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3519 6 are be VBP cord-022526-j9kg00qf 3519 7 usually usually RB cord-022526-j9kg00qf 3519 8 fever fever NN cord-022526-j9kg00qf 3519 9 and and CC cord-022526-j9kg00qf 3519 10 anorexia anorexia NN cord-022526-j9kg00qf 3519 11 . . . cord-022526-j9kg00qf 3520 1 1 1 CD cord-022526-j9kg00qf 3520 2 , , , cord-022526-j9kg00qf 3520 3 15 15 CD cord-022526-j9kg00qf 3520 4 Signs sign NNS cord-022526-j9kg00qf 3520 5 of of IN cord-022526-j9kg00qf 3520 6 colic colic NN cord-022526-j9kg00qf 3520 7 may may MD cord-022526-j9kg00qf 3520 8 be be VB cord-022526-j9kg00qf 3520 9 apparent apparent JJ cord-022526-j9kg00qf 3520 10 early early RB cord-022526-j9kg00qf 3520 11 in in IN cord-022526-j9kg00qf 3520 12 the the DT cord-022526-j9kg00qf 3520 13 course course NN cord-022526-j9kg00qf 3520 14 of of IN cord-022526-j9kg00qf 3520 15 the the DT cord-022526-j9kg00qf 3520 16 disease disease NN cord-022526-j9kg00qf 3520 17 , , , cord-022526-j9kg00qf 3520 18 especially especially RB cord-022526-j9kg00qf 3520 19 if if IN cord-022526-j9kg00qf 3520 20 ileus ileus NNP cord-022526-j9kg00qf 3520 21 is be VBZ cord-022526-j9kg00qf 3520 22 present present JJ cord-022526-j9kg00qf 3520 23 . . . cord-022526-j9kg00qf 3521 1 Clinical clinical JJ cord-022526-j9kg00qf 3521 2 signs sign NNS cord-022526-j9kg00qf 3521 3 of of IN cord-022526-j9kg00qf 3521 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3521 5 are be VBP cord-022526-j9kg00qf 3521 6 common common JJ cord-022526-j9kg00qf 3521 7 and and CC cord-022526-j9kg00qf 3521 8 range range VB cord-022526-j9kg00qf 3521 9 from from IN cord-022526-j9kg00qf 3521 10 fever fever NN cord-022526-j9kg00qf 3521 11 , , , cord-022526-j9kg00qf 3521 12 elevated elevated JJ cord-022526-j9kg00qf 3521 13 heart heart NN cord-022526-j9kg00qf 3521 14 and and CC cord-022526-j9kg00qf 3521 15 respiratory respiratory JJ cord-022526-j9kg00qf 3521 16 rates rate NNS cord-022526-j9kg00qf 3521 17 , , , cord-022526-j9kg00qf 3521 18 poor poor JJ cord-022526-j9kg00qf 3521 19 peripheral peripheral JJ cord-022526-j9kg00qf 3521 20 perfusion perfusion NN cord-022526-j9kg00qf 3521 21 , , , cord-022526-j9kg00qf 3521 22 and and CC cord-022526-j9kg00qf 3521 23 ileus ileus NN cord-022526-j9kg00qf 3521 24 to to TO cord-022526-j9kg00qf 3521 25 fulminant fulminant JJ cord-022526-j9kg00qf 3521 26 and and CC cord-022526-j9kg00qf 3521 27 rapidly rapidly RB cord-022526-j9kg00qf 3521 28 progressive progressive JJ cord-022526-j9kg00qf 3521 29 signs sign NNS cord-022526-j9kg00qf 3521 30 of of IN cord-022526-j9kg00qf 3521 31 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 3521 32 shock shock NN cord-022526-j9kg00qf 3521 33 . . . cord-022526-j9kg00qf 3522 1 Oral oral JJ cord-022526-j9kg00qf 3522 2 mucous mucous JJ cord-022526-j9kg00qf 3522 3 membranes membrane NNS cord-022526-j9kg00qf 3522 4 are be VBP cord-022526-j9kg00qf 3522 5 often often RB cord-022526-j9kg00qf 3522 6 pale pale JJ cord-022526-j9kg00qf 3522 7 with with IN cord-022526-j9kg00qf 3522 8 perigingival perigingival NNP cord-022526-j9kg00qf 3522 9 hyperemia hyperemia NNP cord-022526-j9kg00qf 3522 10 ( ( -LRB- cord-022526-j9kg00qf 3522 11 a a DT cord-022526-j9kg00qf 3522 12 toxic toxic JJ cord-022526-j9kg00qf 3522 13 rim rim NN cord-022526-j9kg00qf 3522 14 ) ) -RRB- cord-022526-j9kg00qf 3522 15 but but CC cord-022526-j9kg00qf 3522 16 may may MD cord-022526-j9kg00qf 3522 17 be be VB cord-022526-j9kg00qf 3522 18 brick brick NN cord-022526-j9kg00qf 3522 19 red red JJ cord-022526-j9kg00qf 3522 20 or or CC cord-022526-j9kg00qf 3522 21 cyanotic cyanotic JJ cord-022526-j9kg00qf 3522 22 , , , cord-022526-j9kg00qf 3522 23 with with IN cord-022526-j9kg00qf 3522 24 prolonged prolonged JJ cord-022526-j9kg00qf 3522 25 capillary capillary JJ cord-022526-j9kg00qf 3522 26 refill refill NN cord-022526-j9kg00qf 3522 27 time time NN cord-022526-j9kg00qf 3522 28 . . . cord-022526-j9kg00qf 3523 1 One one CD cord-022526-j9kg00qf 3523 2 may may MD cord-022526-j9kg00qf 3523 3 note note VB cord-022526-j9kg00qf 3523 4 weakness weakness NN cord-022526-j9kg00qf 3523 5 , , , cord-022526-j9kg00qf 3523 6 muscle muscle NN cord-022526-j9kg00qf 3523 7 fasciculations fasciculation NNS cord-022526-j9kg00qf 3523 8 , , , cord-022526-j9kg00qf 3523 9 cold cold JJ cord-022526-j9kg00qf 3523 10 extremities extremity NNS cord-022526-j9kg00qf 3523 11 , , , cord-022526-j9kg00qf 3523 12 and and CC cord-022526-j9kg00qf 3523 13 other other JJ cord-022526-j9kg00qf 3523 14 signs sign NNS cord-022526-j9kg00qf 3523 15 suggestive suggestive JJ cord-022526-j9kg00qf 3523 16 of of IN cord-022526-j9kg00qf 3523 17 hypotensive hypotensive JJ cord-022526-j9kg00qf 3523 18 shock shock NN cord-022526-j9kg00qf 3523 19 ; ; : cord-022526-j9kg00qf 3523 20 synchronous synchronous JJ cord-022526-j9kg00qf 3523 21 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 3523 22 flutter flutter NN cord-022526-j9kg00qf 3523 23 ; ; : cord-022526-j9kg00qf 3523 24 abdominal abdominal JJ cord-022526-j9kg00qf 3523 25 pain pain NN cord-022526-j9kg00qf 3523 26 ; ; : cord-022526-j9kg00qf 3523 27 and and CC cord-022526-j9kg00qf 3523 28 significant significant JJ cord-022526-j9kg00qf 3523 29 metabolic metabolic JJ cord-022526-j9kg00qf 3523 30 and and CC cord-022526-j9kg00qf 3523 31 electrolyte electrolyte JJ cord-022526-j9kg00qf 3523 32 abnormalities abnormality NNS cord-022526-j9kg00qf 3523 33 in in IN cord-022526-j9kg00qf 3523 34 severe severe JJ cord-022526-j9kg00qf 3523 35 cases case NNS cord-022526-j9kg00qf 3523 36 of of IN cord-022526-j9kg00qf 3523 37 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3523 38 . . . cord-022526-j9kg00qf 3524 1 One one CD cord-022526-j9kg00qf 3524 2 also also RB cord-022526-j9kg00qf 3524 3 may may MD cord-022526-j9kg00qf 3524 4 note note VB cord-022526-j9kg00qf 3524 5 signs sign NNS cord-022526-j9kg00qf 3524 6 of of IN cord-022526-j9kg00qf 3524 7 mild mild JJ cord-022526-j9kg00qf 3524 8 dehydration dehydration NN cord-022526-j9kg00qf 3524 9 before before IN cord-022526-j9kg00qf 3524 10 diarrhea diarrhea NN cord-022526-j9kg00qf 3524 11 is be VBZ cord-022526-j9kg00qf 3524 12 apparent apparent JJ cord-022526-j9kg00qf 3524 13 . . . cord-022526-j9kg00qf 3525 1 Once once IN cord-022526-j9kg00qf 3525 2 diarrhea diarrhea NN cord-022526-j9kg00qf 3525 3 is be VBZ cord-022526-j9kg00qf 3525 4 evident evident JJ cord-022526-j9kg00qf 3525 5 , , , cord-022526-j9kg00qf 3525 6 dehydration dehydration NN cord-022526-j9kg00qf 3525 7 may may MD cord-022526-j9kg00qf 3525 8 become become VB cord-022526-j9kg00qf 3525 9 severe severe JJ cord-022526-j9kg00qf 3525 10 rapidly rapidly RB cord-022526-j9kg00qf 3525 11 . . . cord-022526-j9kg00qf 3526 1 Occasionally occasionally RB cord-022526-j9kg00qf 3526 2 , , , cord-022526-j9kg00qf 3526 3 horses horse NNS cord-022526-j9kg00qf 3526 4 die die VBP cord-022526-j9kg00qf 3526 5 peracutely peracutely RB cord-022526-j9kg00qf 3526 6 , , , cord-022526-j9kg00qf 3526 7 without without IN cord-022526-j9kg00qf 3526 8 developing develop VBG cord-022526-j9kg00qf 3526 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3526 10 . . . cord-022526-j9kg00qf 3527 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3527 2 may may MD cord-022526-j9kg00qf 3527 3 not not RB cord-022526-j9kg00qf 3527 4 be be VB cord-022526-j9kg00qf 3527 5 apparent apparent JJ cord-022526-j9kg00qf 3527 6 for for IN cord-022526-j9kg00qf 3527 7 several several JJ cord-022526-j9kg00qf 3527 8 days day NNS cord-022526-j9kg00qf 3527 9 but but CC cord-022526-j9kg00qf 3527 10 usually usually RB cord-022526-j9kg00qf 3527 11 occurs occur VBZ cord-022526-j9kg00qf 3527 12 by by IN cord-022526-j9kg00qf 3527 13 24 24 CD cord-022526-j9kg00qf 3527 14 to to TO cord-022526-j9kg00qf 3527 15 48 48 CD cord-022526-j9kg00qf 3527 16 hours hour NNS cord-022526-j9kg00qf 3527 17 after after IN cord-022526-j9kg00qf 3527 18 the the DT cord-022526-j9kg00qf 3527 19 fever fever NN cord-022526-j9kg00qf 3527 20 begins begin VBZ cord-022526-j9kg00qf 3527 21 . . . cord-022526-j9kg00qf 3528 1 1 1 CD cord-022526-j9kg00qf 3528 2 , , , cord-022526-j9kg00qf 3528 3 15 15 CD cord-022526-j9kg00qf 3529 1 The the DT cord-022526-j9kg00qf 3529 2 duration duration NN cord-022526-j9kg00qf 3529 3 of of IN cord-022526-j9kg00qf 3529 4 the the DT cord-022526-j9kg00qf 3529 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3529 6 may may MD cord-022526-j9kg00qf 3529 7 be be VB cord-022526-j9kg00qf 3529 8 days day NNS cord-022526-j9kg00qf 3529 9 to to IN cord-022526-j9kg00qf 3529 10 weeks week NNS cord-022526-j9kg00qf 3529 11 . . . cord-022526-j9kg00qf 3530 1 The the DT cord-022526-j9kg00qf 3530 2 character character NN cord-022526-j9kg00qf 3530 3 of of IN cord-022526-j9kg00qf 3530 4 the the DT cord-022526-j9kg00qf 3530 5 first first JJ cord-022526-j9kg00qf 3530 6 diarrheal diarrheal JJ cord-022526-j9kg00qf 3530 7 feces fece NNS cord-022526-j9kg00qf 3530 8 is be VBZ cord-022526-j9kg00qf 3530 9 usually usually RB cord-022526-j9kg00qf 3530 10 watery watery JJ cord-022526-j9kg00qf 3530 11 with with IN cord-022526-j9kg00qf 3530 12 particles particle NNS cord-022526-j9kg00qf 3530 13 of of IN cord-022526-j9kg00qf 3530 14 roughage roughage NN cord-022526-j9kg00qf 3530 15 but but CC cord-022526-j9kg00qf 3530 16 may may MD cord-022526-j9kg00qf 3530 17 become become VB cord-022526-j9kg00qf 3530 18 fluid fluid NN cord-022526-j9kg00qf 3530 19 rapidly rapidly RB cord-022526-j9kg00qf 3530 20 without without IN cord-022526-j9kg00qf 3530 21 solid solid JJ cord-022526-j9kg00qf 3530 22 material material NN cord-022526-j9kg00qf 3530 23 . . . cord-022526-j9kg00qf 3531 1 Finding find VBG cord-022526-j9kg00qf 3531 2 frank frank JJ cord-022526-j9kg00qf 3531 3 blood blood NN cord-022526-j9kg00qf 3531 4 and and CC cord-022526-j9kg00qf 3531 5 fibrin fibrin NN cord-022526-j9kg00qf 3531 6 in in IN cord-022526-j9kg00qf 3531 7 the the DT cord-022526-j9kg00qf 3531 8 feces fece NNS cord-022526-j9kg00qf 3531 9 is be VBZ cord-022526-j9kg00qf 3531 10 unusual unusual JJ cord-022526-j9kg00qf 3531 11 . . . cord-022526-j9kg00qf 3532 1 The the DT cord-022526-j9kg00qf 3532 2 volume volume NN cord-022526-j9kg00qf 3532 3 of of IN cord-022526-j9kg00qf 3532 4 feces fece NNS cord-022526-j9kg00qf 3532 5 is be VBZ cord-022526-j9kg00qf 3532 6 often often RB cord-022526-j9kg00qf 3532 7 large large JJ cord-022526-j9kg00qf 3532 8 , , , cord-022526-j9kg00qf 3532 9 with with IN cord-022526-j9kg00qf 3532 10 frequent frequent JJ cord-022526-j9kg00qf 3532 11 defecation defecation NN cord-022526-j9kg00qf 3532 12 . . . cord-022526-j9kg00qf 3533 1 One one CD cord-022526-j9kg00qf 3533 2 may may MD cord-022526-j9kg00qf 3533 3 note note VB cord-022526-j9kg00qf 3533 4 straining straining NN cord-022526-j9kg00qf 3533 5 or or CC cord-022526-j9kg00qf 3533 6 signs sign NNS cord-022526-j9kg00qf 3533 7 of of IN cord-022526-j9kg00qf 3533 8 colic colic NN cord-022526-j9kg00qf 3533 9 when when WRB cord-022526-j9kg00qf 3533 10 the the DT cord-022526-j9kg00qf 3533 11 patient patient NN cord-022526-j9kg00qf 3533 12 is be VBZ cord-022526-j9kg00qf 3533 13 defecating defecate VBG cord-022526-j9kg00qf 3533 14 , , , cord-022526-j9kg00qf 3533 15 and and CC cord-022526-j9kg00qf 3533 16 rectal rectal JJ cord-022526-j9kg00qf 3533 17 prolapse prolapse NN cord-022526-j9kg00qf 3533 18 may may MD cord-022526-j9kg00qf 3533 19 occur occur VB cord-022526-j9kg00qf 3533 20 occasionally occasionally RB cord-022526-j9kg00qf 3533 21 . . . cord-022526-j9kg00qf 3534 1 Persistent persistent JJ cord-022526-j9kg00qf 3534 2 straining straining NN cord-022526-j9kg00qf 3534 3 and and CC cord-022526-j9kg00qf 3534 4 rectal rectal JJ cord-022526-j9kg00qf 3534 5 prolapse prolapse NN cord-022526-j9kg00qf 3534 6 may may MD cord-022526-j9kg00qf 3534 7 be be VB cord-022526-j9kg00qf 3534 8 a a DT cord-022526-j9kg00qf 3534 9 sign sign NN cord-022526-j9kg00qf 3534 10 of of IN cord-022526-j9kg00qf 3534 11 colonic colonic JJ cord-022526-j9kg00qf 3534 12 infarction infarction NN cord-022526-j9kg00qf 3534 13 . . . cord-022526-j9kg00qf 3535 1 Abdominal abdominal JJ cord-022526-j9kg00qf 3535 2 borborygmi borborygmi NN cord-022526-j9kg00qf 3535 3 are be VBP cord-022526-j9kg00qf 3535 4 often often RB cord-022526-j9kg00qf 3535 5 absent absent JJ cord-022526-j9kg00qf 3535 6 early early RB cord-022526-j9kg00qf 3535 7 in in IN cord-022526-j9kg00qf 3535 8 the the DT cord-022526-j9kg00qf 3535 9 course course NN cord-022526-j9kg00qf 3535 10 of of IN cord-022526-j9kg00qf 3535 11 the the DT cord-022526-j9kg00qf 3535 12 disease disease NN cord-022526-j9kg00qf 3535 13 because because IN cord-022526-j9kg00qf 3535 14 of of IN cord-022526-j9kg00qf 3535 15 ileus ileus NNP cord-022526-j9kg00qf 3535 16 but but CC cord-022526-j9kg00qf 3535 17 become become VBP cord-022526-j9kg00qf 3535 18 evident evident JJ cord-022526-j9kg00qf 3535 19 later later RB cord-022526-j9kg00qf 3535 20 , , , cord-022526-j9kg00qf 3535 21 usually usually RB cord-022526-j9kg00qf 3535 22 when when WRB cord-022526-j9kg00qf 3535 23 diarrhea diarrhea NN cord-022526-j9kg00qf 3535 24 begins begin VBZ cord-022526-j9kg00qf 3535 25 . . . cord-022526-j9kg00qf 3536 1 Fluid fluid NN cord-022526-j9kg00qf 3536 2 and and CC cord-022526-j9kg00qf 3536 3 gas gas NN cord-022526-j9kg00qf 3536 4 sounds sound NNS cord-022526-j9kg00qf 3536 5 are be VBP cord-022526-j9kg00qf 3536 6 commonly commonly RB cord-022526-j9kg00qf 3536 7 audible audible JJ cord-022526-j9kg00qf 3536 8 , , , cord-022526-j9kg00qf 3536 9 but but CC cord-022526-j9kg00qf 3536 10 normal normal JJ cord-022526-j9kg00qf 3536 11 progressive progressive JJ cord-022526-j9kg00qf 3536 12 motility motility NN cord-022526-j9kg00qf 3536 13 is be VBZ cord-022526-j9kg00qf 3536 14 less less RBR cord-022526-j9kg00qf 3536 15 frequently frequently RB cord-022526-j9kg00qf 3536 16 audible audible JJ cord-022526-j9kg00qf 3536 17 than than IN cord-022526-j9kg00qf 3536 18 normally normally RB cord-022526-j9kg00qf 3536 19 . . . cord-022526-j9kg00qf 3537 1 Transrectal transrectal JJ cord-022526-j9kg00qf 3537 2 palpation palpation NN cord-022526-j9kg00qf 3537 3 may may MD cord-022526-j9kg00qf 3537 4 reveal reveal VB cord-022526-j9kg00qf 3537 5 edematous edematous JJ cord-022526-j9kg00qf 3537 6 rectal rectal JJ cord-022526-j9kg00qf 3537 7 mucosa mucosa NN cord-022526-j9kg00qf 3537 8 and and CC cord-022526-j9kg00qf 3537 9 colon colon NN cord-022526-j9kg00qf 3537 10 and and CC cord-022526-j9kg00qf 3537 11 fluid fluid NN cord-022526-j9kg00qf 3537 12 - - HYPH cord-022526-j9kg00qf 3537 13 filled fill VBN cord-022526-j9kg00qf 3537 14 colon colon NN cord-022526-j9kg00qf 3537 15 and and CC cord-022526-j9kg00qf 3537 16 cecum cecum NN cord-022526-j9kg00qf 3537 17 . . . cord-022526-j9kg00qf 3538 1 One one CD cord-022526-j9kg00qf 3538 2 may may MD cord-022526-j9kg00qf 3538 3 obtain obtain VB cord-022526-j9kg00qf 3538 4 gastric gastric JJ cord-022526-j9kg00qf 3538 5 reflux reflux NN cord-022526-j9kg00qf 3538 6 , , , cord-022526-j9kg00qf 3538 7 especially especially RB cord-022526-j9kg00qf 3538 8 early early RB cord-022526-j9kg00qf 3538 9 in in IN cord-022526-j9kg00qf 3538 10 the the DT cord-022526-j9kg00qf 3538 11 course course NN cord-022526-j9kg00qf 3538 12 when when WRB cord-022526-j9kg00qf 3538 13 ileus ileus NNP cord-022526-j9kg00qf 3538 14 is be VBZ cord-022526-j9kg00qf 3538 15 evident evident JJ cord-022526-j9kg00qf 3538 16 . . . cord-022526-j9kg00qf 3539 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 3539 2 abnormalities abnormality NNS cord-022526-j9kg00qf 3539 3 early early RB cord-022526-j9kg00qf 3539 4 in in IN cord-022526-j9kg00qf 3539 5 the the DT cord-022526-j9kg00qf 3539 6 course course NN cord-022526-j9kg00qf 3539 7 of of IN cord-022526-j9kg00qf 3539 8 the the DT cord-022526-j9kg00qf 3539 9 disease disease NN cord-022526-j9kg00qf 3539 10 include include VBP cord-022526-j9kg00qf 3539 11 moderate moderate JJ cord-022526-j9kg00qf 3539 12 to to IN cord-022526-j9kg00qf 3539 13 severe severe JJ cord-022526-j9kg00qf 3539 14 neutropenia neutropenia NN cord-022526-j9kg00qf 3539 15 , , , cord-022526-j9kg00qf 3539 16 lymphopenia lymphopenia NNP cord-022526-j9kg00qf 3539 17 , , , cord-022526-j9kg00qf 3539 18 and and CC cord-022526-j9kg00qf 3539 19 leukopenia leukopenia NN cord-022526-j9kg00qf 3539 20 , , , cord-022526-j9kg00qf 3539 21 a a DT cord-022526-j9kg00qf 3539 22 mild mild JJ cord-022526-j9kg00qf 3539 23 to to TO cord-022526-j9kg00qf 3539 24 moderate moderate JJ cord-022526-j9kg00qf 3539 25 left left JJ cord-022526-j9kg00qf 3539 26 shift shift NN cord-022526-j9kg00qf 3539 27 , , , cord-022526-j9kg00qf 3539 28 and and CC cord-022526-j9kg00qf 3539 29 toxic toxic JJ cord-022526-j9kg00qf 3539 30 changes change NNS cord-022526-j9kg00qf 3539 31 in in IN cord-022526-j9kg00qf 3539 32 the the DT cord-022526-j9kg00qf 3539 33 neutrophils neutrophil NNS cord-022526-j9kg00qf 3539 34 . . . cord-022526-j9kg00qf 3540 1 1 1 CD cord-022526-j9kg00qf 3540 2 , , , cord-022526-j9kg00qf 3540 3 15 15 CD cord-022526-j9kg00qf 3540 4 Thrombocytopenia Thrombocytopenia NNP cord-022526-j9kg00qf 3540 5 , , , cord-022526-j9kg00qf 3540 6 moderate moderate JJ cord-022526-j9kg00qf 3540 7 to to IN cord-022526-j9kg00qf 3540 8 severe severe JJ cord-022526-j9kg00qf 3540 9 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 3540 10 , , , cord-022526-j9kg00qf 3540 11 and and CC cord-022526-j9kg00qf 3540 12 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 3540 13 are be VBP cord-022526-j9kg00qf 3540 14 also also RB cord-022526-j9kg00qf 3540 15 common common JJ cord-022526-j9kg00qf 3540 16 . . . cord-022526-j9kg00qf 3541 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 3541 2 is be VBZ cord-022526-j9kg00qf 3541 3 an an DT cord-022526-j9kg00qf 3541 4 early early JJ cord-022526-j9kg00qf 3541 5 but but CC cord-022526-j9kg00qf 3541 6 nonspecific nonspecific JJ cord-022526-j9kg00qf 3541 7 indicator indicator NN cord-022526-j9kg00qf 3541 8 of of IN cord-022526-j9kg00qf 3541 9 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3541 10 , , , cord-022526-j9kg00qf 3541 11 often often RB cord-022526-j9kg00qf 3541 12 occurring occur VBG cord-022526-j9kg00qf 3541 13 concurrently concurrently RB cord-022526-j9kg00qf 3541 14 with with IN cord-022526-j9kg00qf 3541 15 the the DT cord-022526-j9kg00qf 3541 16 onset onset NN cord-022526-j9kg00qf 3541 17 of of IN cord-022526-j9kg00qf 3541 18 fever fever NN cord-022526-j9kg00qf 3541 19 . . . cord-022526-j9kg00qf 3542 1 1 1 LS cord-022526-j9kg00qf 3543 1 Later later RB cord-022526-j9kg00qf 3543 2 in in IN cord-022526-j9kg00qf 3543 3 the the DT cord-022526-j9kg00qf 3543 4 course course NN cord-022526-j9kg00qf 3543 5 of of IN cord-022526-j9kg00qf 3543 6 disease disease NN cord-022526-j9kg00qf 3543 7 , , , cord-022526-j9kg00qf 3543 8 one one PRP cord-022526-j9kg00qf 3543 9 may may MD cord-022526-j9kg00qf 3543 10 see see VB cord-022526-j9kg00qf 3543 11 neutrophilic neutrophilic NNP cord-022526-j9kg00qf 3543 12 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 3543 13 , , , cord-022526-j9kg00qf 3543 14 indicating indicate VBG cord-022526-j9kg00qf 3543 15 recovery recovery NN cord-022526-j9kg00qf 3543 16 . . . cord-022526-j9kg00qf 3544 1 A a DT cord-022526-j9kg00qf 3544 2 degenerative degenerative JJ cord-022526-j9kg00qf 3544 3 left left JJ cord-022526-j9kg00qf 3544 4 shift shift NN cord-022526-j9kg00qf 3544 5 , , , cord-022526-j9kg00qf 3544 6 with with IN cord-022526-j9kg00qf 3544 7 metamyelocytes metamyelocytes NNP cord-022526-j9kg00qf 3544 8 and and CC cord-022526-j9kg00qf 3544 9 myelocytes myelocytes NNPS cord-022526-j9kg00qf 3544 10 in in IN cord-022526-j9kg00qf 3544 11 the the DT cord-022526-j9kg00qf 3544 12 peripheral peripheral JJ cord-022526-j9kg00qf 3544 13 blood blood NN cord-022526-j9kg00qf 3544 14 , , , cord-022526-j9kg00qf 3544 15 is be VBZ cord-022526-j9kg00qf 3544 16 a a DT cord-022526-j9kg00qf 3544 17 poor poor JJ cord-022526-j9kg00qf 3544 18 prognostic prognostic JJ cord-022526-j9kg00qf 3544 19 sign sign NN cord-022526-j9kg00qf 3544 20 . . . cord-022526-j9kg00qf 3545 1 Serum serum NN cord-022526-j9kg00qf 3545 2 biochemical biochemical JJ cord-022526-j9kg00qf 3545 3 analysis analysis NN cord-022526-j9kg00qf 3545 4 may may MD cord-022526-j9kg00qf 3545 5 reveal reveal VB cord-022526-j9kg00qf 3545 6 azotemia azotemia NN cord-022526-j9kg00qf 3545 7 , , , cord-022526-j9kg00qf 3545 8 elevations elevation NNS cord-022526-j9kg00qf 3545 9 in in IN cord-022526-j9kg00qf 3545 10 serum serum NN cord-022526-j9kg00qf 3545 11 sorbitol sorbitol NN cord-022526-j9kg00qf 3545 12 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 3545 13 and and CC cord-022526-j9kg00qf 3545 14 γglutamine γglutamine NNP cord-022526-j9kg00qf 3545 15 aminotransferase aminotransferase NN cord-022526-j9kg00qf 3545 16 activity activity NN cord-022526-j9kg00qf 3545 17 , , , cord-022526-j9kg00qf 3545 18 and and CC cord-022526-j9kg00qf 3545 19 elevated elevated JJ cord-022526-j9kg00qf 3545 20 serum serum NN cord-022526-j9kg00qf 3545 21 lactic lactic NN cord-022526-j9kg00qf 3545 22 acid acid NN cord-022526-j9kg00qf 3545 23 concentration concentration NN cord-022526-j9kg00qf 3545 24 . . . cord-022526-j9kg00qf 3546 1 Azotemia Azotemia NNP cord-022526-j9kg00qf 3546 2 is be VBZ cord-022526-j9kg00qf 3546 3 often often RB cord-022526-j9kg00qf 3546 4 prerenal prerenal JJ cord-022526-j9kg00qf 3546 5 , , , cord-022526-j9kg00qf 3546 6 but but CC cord-022526-j9kg00qf 3546 7 acute acute JJ cord-022526-j9kg00qf 3546 8 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 3546 9 renal renal JJ cord-022526-j9kg00qf 3546 10 failure failure NN cord-022526-j9kg00qf 3546 11 may may MD cord-022526-j9kg00qf 3546 12 occur occur VB cord-022526-j9kg00qf 3546 13 in in IN cord-022526-j9kg00qf 3546 14 severely severely RB cord-022526-j9kg00qf 3546 15 dehydrated dehydrate VBN cord-022526-j9kg00qf 3546 16 , , , cord-022526-j9kg00qf 3546 17 endotoxemic endotoxemic NNP cord-022526-j9kg00qf 3546 18 , , , cord-022526-j9kg00qf 3546 19 or or CC cord-022526-j9kg00qf 3546 20 septicemic septicemic JJ cord-022526-j9kg00qf 3546 21 patients patient NNS cord-022526-j9kg00qf 3546 22 . . . cord-022526-j9kg00qf 3547 1 Indeed indeed RB cord-022526-j9kg00qf 3547 2 , , , cord-022526-j9kg00qf 3547 3 elevation elevation NN cord-022526-j9kg00qf 3547 4 of of IN cord-022526-j9kg00qf 3547 5 creatinine creatinine NN cord-022526-j9kg00qf 3547 6 concentration concentration NN cord-022526-j9kg00qf 3547 7 is be VBZ cord-022526-j9kg00qf 3547 8 a a DT cord-022526-j9kg00qf 3547 9 poor poor JJ cord-022526-j9kg00qf 3547 10 prognostic prognostic JJ cord-022526-j9kg00qf 3547 11 indicator indicator NN cord-022526-j9kg00qf 3547 12 in in IN cord-022526-j9kg00qf 3547 13 horses horse NNS cord-022526-j9kg00qf 3547 14 with with IN cord-022526-j9kg00qf 3547 15 acute acute JJ cord-022526-j9kg00qf 3547 16 colitis colitis NN cord-022526-j9kg00qf 3547 17 . . . cord-022526-j9kg00qf 3548 1 43 43 CD cord-022526-j9kg00qf 3549 1 Hemodynamic Hemodynamic NNP cord-022526-j9kg00qf 3549 2 renal renal JJ cord-022526-j9kg00qf 3549 3 disease disease NN cord-022526-j9kg00qf 3549 4 may may MD cord-022526-j9kg00qf 3549 5 be be VB cord-022526-j9kg00qf 3549 6 complicated complicate VBN cord-022526-j9kg00qf 3549 7 by by IN cord-022526-j9kg00qf 3549 8 toxic toxic JJ cord-022526-j9kg00qf 3549 9 injury injury NN cord-022526-j9kg00qf 3549 10 caused cause VBN cord-022526-j9kg00qf 3549 11 by by IN cord-022526-j9kg00qf 3549 12 administration administration NN cord-022526-j9kg00qf 3549 13 of of IN cord-022526-j9kg00qf 3549 14 nephrotoxic nephrotoxic NNP cord-022526-j9kg00qf 3549 15 drugs drug NNS cord-022526-j9kg00qf 3549 16 . . . cord-022526-j9kg00qf 3550 1 Hyponatremia hyponatremia NN cord-022526-j9kg00qf 3550 2 may may MD cord-022526-j9kg00qf 3550 3 also also RB cord-022526-j9kg00qf 3550 4 contribute contribute VB cord-022526-j9kg00qf 3550 5 to to IN cord-022526-j9kg00qf 3550 6 prerenal prerenal NNP cord-022526-j9kg00qf 3550 7 azotemia azotemia NNP cord-022526-j9kg00qf 3550 8 . . . cord-022526-j9kg00qf 3551 1 Elevations elevation NNS cord-022526-j9kg00qf 3551 2 in in IN cord-022526-j9kg00qf 3551 3 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 3551 4 enzymes enzyme NNS cord-022526-j9kg00qf 3551 5 are be VBP cord-022526-j9kg00qf 3551 6 usually usually RB cord-022526-j9kg00qf 3551 7 mild mild JJ cord-022526-j9kg00qf 3551 8 and and CC cord-022526-j9kg00qf 3551 9 reflect reflect VBP cord-022526-j9kg00qf 3551 10 damage damage NN cord-022526-j9kg00qf 3551 11 to to IN cord-022526-j9kg00qf 3551 12 the the DT cord-022526-j9kg00qf 3551 13 hepatocytes hepatocyte NNS cord-022526-j9kg00qf 3551 14 from from IN cord-022526-j9kg00qf 3551 15 absorbed absorb VBN cord-022526-j9kg00qf 3551 16 toxins toxin NNS cord-022526-j9kg00qf 3551 17 such such JJ cord-022526-j9kg00qf 3551 18 as as IN cord-022526-j9kg00qf 3551 19 endotoxin endotoxin NN cord-022526-j9kg00qf 3551 20 and and CC cord-022526-j9kg00qf 3551 21 from from IN cord-022526-j9kg00qf 3551 22 poor poor JJ cord-022526-j9kg00qf 3551 23 perfusion perfusion NN cord-022526-j9kg00qf 3551 24 caused cause VBN cord-022526-j9kg00qf 3551 25 by by IN cord-022526-j9kg00qf 3551 26 hypotensive hypotensive JJ cord-022526-j9kg00qf 3551 27 shock shock NN cord-022526-j9kg00qf 3551 28 or or CC cord-022526-j9kg00qf 3551 29 dehydration dehydration NN cord-022526-j9kg00qf 3551 30 . . . cord-022526-j9kg00qf 3552 1 Lactic lactic JJ cord-022526-j9kg00qf 3552 2 acidemia acidemia NN cord-022526-j9kg00qf 3552 3 may may MD cord-022526-j9kg00qf 3552 4 be be VB cord-022526-j9kg00qf 3552 5 present present JJ cord-022526-j9kg00qf 3552 6 , , , cord-022526-j9kg00qf 3552 7 reflecting reflect VBG cord-022526-j9kg00qf 3552 8 poor poor JJ cord-022526-j9kg00qf 3552 9 tissue tissue NN cord-022526-j9kg00qf 3552 10 perfusion perfusion NN cord-022526-j9kg00qf 3552 11 . . . cord-022526-j9kg00qf 3553 1 Plasma plasma NN cord-022526-j9kg00qf 3553 2 protein protein NN cord-022526-j9kg00qf 3553 3 rapidly rapidly RB cord-022526-j9kg00qf 3553 4 drops drop VBZ cord-022526-j9kg00qf 3553 5 as as IN cord-022526-j9kg00qf 3553 6 protein protein NN cord-022526-j9kg00qf 3553 7 is be VBZ cord-022526-j9kg00qf 3553 8 lost lose VBN cord-022526-j9kg00qf 3553 9 in in IN cord-022526-j9kg00qf 3553 10 the the DT cord-022526-j9kg00qf 3553 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3553 12 tract tract NN cord-022526-j9kg00qf 3553 13 , , , cord-022526-j9kg00qf 3553 14 causing cause VBG cord-022526-j9kg00qf 3553 15 moderate moderate JJ cord-022526-j9kg00qf 3553 16 to to IN cord-022526-j9kg00qf 3553 17 severe severe JJ cord-022526-j9kg00qf 3553 18 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3553 19 and and CC cord-022526-j9kg00qf 3553 20 hypoglobulinemia hypoglobulinemia NN cord-022526-j9kg00qf 3553 21 . . . cord-022526-j9kg00qf 3554 1 Peripheral peripheral JJ cord-022526-j9kg00qf 3554 2 or or CC cord-022526-j9kg00qf 3554 3 organ organ NN cord-022526-j9kg00qf 3554 4 edema edema NN cord-022526-j9kg00qf 3554 5 ( ( -LRB- cord-022526-j9kg00qf 3554 6 vascular vascular JJ cord-022526-j9kg00qf 3554 7 leak leak NN cord-022526-j9kg00qf 3554 8 syndrome syndrome NN cord-022526-j9kg00qf 3554 9 ) ) -RRB- cord-022526-j9kg00qf 3554 10 may may MD cord-022526-j9kg00qf 3554 11 occur occur VB cord-022526-j9kg00qf 3554 12 if if IN cord-022526-j9kg00qf 3554 13 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 3554 14 is be VBZ cord-022526-j9kg00qf 3554 15 severe severe JJ cord-022526-j9kg00qf 3554 16 , , , cord-022526-j9kg00qf 3554 17 coupled couple VBN cord-022526-j9kg00qf 3554 18 with with IN cord-022526-j9kg00qf 3554 19 increases increase NNS cord-022526-j9kg00qf 3554 20 in in IN cord-022526-j9kg00qf 3554 21 endothelial endothelial JJ cord-022526-j9kg00qf 3554 22 permeability permeability NN cord-022526-j9kg00qf 3554 23 induced induce VBN cord-022526-j9kg00qf 3554 24 by by IN cord-022526-j9kg00qf 3554 25 systemic systemic JJ cord-022526-j9kg00qf 3554 26 inflammation inflammation NN cord-022526-j9kg00qf 3554 27 . . . cord-022526-j9kg00qf 3555 1 Hypokalemia Hypokalemia NNP cord-022526-j9kg00qf 3555 2 , , , cord-022526-j9kg00qf 3555 3 hyponatremia hyponatremia NN cord-022526-j9kg00qf 3555 4 , , , cord-022526-j9kg00qf 3555 5 hypochloridemia hypochloridemia NN cord-022526-j9kg00qf 3555 6 , , , cord-022526-j9kg00qf 3555 7 and and CC cord-022526-j9kg00qf 3555 8 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 3555 9 are be VBP cord-022526-j9kg00qf 3555 10 common common JJ cord-022526-j9kg00qf 3555 11 electrolyte electrolyte JJ cord-022526-j9kg00qf 3555 12 abnormalities abnormality NNS cord-022526-j9kg00qf 3555 13 in in IN cord-022526-j9kg00qf 3555 14 patients patient NNS cord-022526-j9kg00qf 3555 15 with with IN cord-022526-j9kg00qf 3555 16 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3555 17 . . . cord-022526-j9kg00qf 3556 1 Metabolic metabolic JJ cord-022526-j9kg00qf 3556 2 acidosis acidosis NN cord-022526-j9kg00qf 3556 3 also also RB cord-022526-j9kg00qf 3556 4 may may MD cord-022526-j9kg00qf 3556 5 be be VB cord-022526-j9kg00qf 3556 6 present present JJ cord-022526-j9kg00qf 3556 7 . . . cord-022526-j9kg00qf 3557 1 Coagulopathies coagulopathie NNS cord-022526-j9kg00qf 3557 2 , , , cord-022526-j9kg00qf 3557 3 such such JJ cord-022526-j9kg00qf 3557 4 as as IN cord-022526-j9kg00qf 3557 5 decreased decrease VBN cord-022526-j9kg00qf 3557 6 antithrombin antithrombin NN cord-022526-j9kg00qf 3557 7 III iii CD cord-022526-j9kg00qf 3557 8 activity activity NN cord-022526-j9kg00qf 3557 9 and and CC cord-022526-j9kg00qf 3557 10 disseminated disseminate VBD cord-022526-j9kg00qf 3557 11 intravascular intravascular JJ cord-022526-j9kg00qf 3557 12 coagulation coagulation NN cord-022526-j9kg00qf 3557 13 , , , cord-022526-j9kg00qf 3557 14 may may MD cord-022526-j9kg00qf 3557 15 occur occur VB cord-022526-j9kg00qf 3557 16 . . . cord-022526-j9kg00qf 3558 1 Urinalysis Urinalysis NNP cord-022526-j9kg00qf 3558 2 may may MD cord-022526-j9kg00qf 3558 3 reveal reveal VB cord-022526-j9kg00qf 3558 4 isosthenuria isosthenuria NNS cord-022526-j9kg00qf 3558 5 , , , cord-022526-j9kg00qf 3558 6 proteinuria proteinuria NN cord-022526-j9kg00qf 3558 7 , , , cord-022526-j9kg00qf 3558 8 hematuria hematuria NN cord-022526-j9kg00qf 3558 9 , , , cord-022526-j9kg00qf 3558 10 cylindruria cylindruria NNP cord-022526-j9kg00qf 3558 11 , , , cord-022526-j9kg00qf 3558 12 and and CC cord-022526-j9kg00qf 3558 13 glucosuria glucosuria NN cord-022526-j9kg00qf 3558 14 if if IN cord-022526-j9kg00qf 3558 15 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 3558 16 or or CC cord-022526-j9kg00qf 3558 17 toxic toxic JJ cord-022526-j9kg00qf 3558 18 renal renal JJ cord-022526-j9kg00qf 3558 19 injury injury NN cord-022526-j9kg00qf 3558 20 is be VBZ cord-022526-j9kg00qf 3558 21 present present JJ cord-022526-j9kg00qf 3558 22 . . . cord-022526-j9kg00qf 3559 1 The the DT cord-022526-j9kg00qf 3559 2 number number NN cord-022526-j9kg00qf 3559 3 of of IN cord-022526-j9kg00qf 3559 4 leukocytes leukocyte NNS cord-022526-j9kg00qf 3559 5 in in IN cord-022526-j9kg00qf 3559 6 the the DT cord-022526-j9kg00qf 3559 7 feces fece NNS cord-022526-j9kg00qf 3559 8 usually usually RB cord-022526-j9kg00qf 3559 9 is be VBZ cord-022526-j9kg00qf 3559 10 elevated elevate VBN cord-022526-j9kg00qf 3559 11 , , , cord-022526-j9kg00qf 3559 12 and and CC cord-022526-j9kg00qf 3559 13 occult occult JJ cord-022526-j9kg00qf 3559 14 blood blood NN cord-022526-j9kg00qf 3559 15 may may MD cord-022526-j9kg00qf 3559 16 be be VB cord-022526-j9kg00qf 3559 17 detectable detectable JJ cord-022526-j9kg00qf 3559 18 . . . cord-022526-j9kg00qf 3560 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 3560 2 fluid fluid NN cord-022526-j9kg00qf 3560 3 is be VBZ cord-022526-j9kg00qf 3560 4 usually usually RB cord-022526-j9kg00qf 3560 5 normal normal JJ cord-022526-j9kg00qf 3560 6 except except IN cord-022526-j9kg00qf 3560 7 when when WRB cord-022526-j9kg00qf 3560 8 severe severe JJ cord-022526-j9kg00qf 3560 9 mural mural NN cord-022526-j9kg00qf 3560 10 inflammation inflammation NN cord-022526-j9kg00qf 3560 11 or or CC cord-022526-j9kg00qf 3560 12 colonic colonic JJ cord-022526-j9kg00qf 3560 13 infarction infarction NN cord-022526-j9kg00qf 3560 14 occurs occur VBZ cord-022526-j9kg00qf 3560 15 . . . cord-022526-j9kg00qf 3561 1 Routine routine JJ cord-022526-j9kg00qf 3561 2 detection detection NN cord-022526-j9kg00qf 3561 3 of of IN cord-022526-j9kg00qf 3561 4 salmonellae salmonellae NNP cord-022526-j9kg00qf 3561 5 in in IN cord-022526-j9kg00qf 3561 6 feces fece NNS cord-022526-j9kg00qf 3561 7 involves involve VBZ cord-022526-j9kg00qf 3561 8 five five CD cord-022526-j9kg00qf 3561 9 daily daily JJ cord-022526-j9kg00qf 3561 10 cultures culture NNS cord-022526-j9kg00qf 3561 11 of of IN cord-022526-j9kg00qf 3561 12 large large JJ cord-022526-j9kg00qf 3561 13 samples sample NNS cord-022526-j9kg00qf 3561 14 ( ( -LRB- cord-022526-j9kg00qf 3561 15 10 10 CD cord-022526-j9kg00qf 3561 16 to to TO cord-022526-j9kg00qf 3561 17 30 30 CD cord-022526-j9kg00qf 3561 18 g g NN cord-022526-j9kg00qf 3561 19 ) ) -RRB- cord-022526-j9kg00qf 3561 20 of of IN cord-022526-j9kg00qf 3561 21 feces fece NNS cord-022526-j9kg00qf 3561 22 using use VBG cord-022526-j9kg00qf 3561 23 enrichment enrichment NN cord-022526-j9kg00qf 3561 24 techniques technique NNS cord-022526-j9kg00qf 3561 25 . . . cord-022526-j9kg00qf 3562 1 1 1 CD cord-022526-j9kg00qf 3562 2 , , , cord-022526-j9kg00qf 3562 3 44 44 CD cord-022526-j9kg00qf 3562 4 , , , cord-022526-j9kg00qf 3562 5 45 45 CD cord-022526-j9kg00qf 3563 1 However however RB cord-022526-j9kg00qf 3563 2 , , , cord-022526-j9kg00qf 3563 3 the the DT cord-022526-j9kg00qf 3563 4 sensitivity sensitivity NN cord-022526-j9kg00qf 3563 5 of of IN cord-022526-j9kg00qf 3563 6 fecal fecal JJ cord-022526-j9kg00qf 3563 7 culture culture NN cord-022526-j9kg00qf 3563 8 can can MD cord-022526-j9kg00qf 3563 9 be be VB cord-022526-j9kg00qf 3563 10 as as RB cord-022526-j9kg00qf 3563 11 low low JJ cord-022526-j9kg00qf 3563 12 as as IN cord-022526-j9kg00qf 3563 13 30 30 CD cord-022526-j9kg00qf 3563 14 % % NN cord-022526-j9kg00qf 3563 15 to to TO cord-022526-j9kg00qf 3563 16 50 50 CD cord-022526-j9kg00qf 3563 17 % % NN cord-022526-j9kg00qf 3563 18 , , , cord-022526-j9kg00qf 3563 19 even even RB cord-022526-j9kg00qf 3563 20 if if IN cord-022526-j9kg00qf 3563 21 one one CD cord-022526-j9kg00qf 3563 22 cultures culture NNS cord-022526-j9kg00qf 3563 23 several several JJ cord-022526-j9kg00qf 3563 24 fecal fecal JJ cord-022526-j9kg00qf 3563 25 samples sample NNS cord-022526-j9kg00qf 3563 26 collected collect VBN cord-022526-j9kg00qf 3563 27 daily daily RB cord-022526-j9kg00qf 3563 28 . . . cord-022526-j9kg00qf 3564 1 Concurrent concurrent JJ cord-022526-j9kg00qf 3564 2 culture culture NN cord-022526-j9kg00qf 3564 3 of of IN cord-022526-j9kg00qf 3564 4 rectal rectal JJ cord-022526-j9kg00qf 3564 5 biopsy biopsy NN cord-022526-j9kg00qf 3564 6 specimens specimen NNS cord-022526-j9kg00qf 3564 7 and and CC cord-022526-j9kg00qf 3564 8 feces fece NNS cord-022526-j9kg00qf 3564 9 increases increase VBZ cord-022526-j9kg00qf 3564 10 the the DT cord-022526-j9kg00qf 3564 11 sensitivity sensitivity NN cord-022526-j9kg00qf 3564 12 of of IN cord-022526-j9kg00qf 3564 13 culture culture NN cord-022526-j9kg00qf 3564 14 techniques technique NNS cord-022526-j9kg00qf 3564 15 to to IN cord-022526-j9kg00qf 3564 16 60 60 CD cord-022526-j9kg00qf 3564 17 % % NN cord-022526-j9kg00qf 3564 18 to to TO cord-022526-j9kg00qf 3564 19 75 75 CD cord-022526-j9kg00qf 3564 20 % % NN cord-022526-j9kg00qf 3564 21 . . . cord-022526-j9kg00qf 3565 1 45 45 CD cord-022526-j9kg00qf 3566 1 Currently currently RB cord-022526-j9kg00qf 3566 2 , , , cord-022526-j9kg00qf 3566 3 the the DT cord-022526-j9kg00qf 3566 4 polymerase polymerase NN cord-022526-j9kg00qf 3566 5 chain chain NN cord-022526-j9kg00qf 3566 6 reaction reaction NN cord-022526-j9kg00qf 3566 7 ( ( -LRB- cord-022526-j9kg00qf 3566 8 PCR PCR NNP cord-022526-j9kg00qf 3566 9 ) ) -RRB- cord-022526-j9kg00qf 3566 10 is be VBZ cord-022526-j9kg00qf 3566 11 the the DT cord-022526-j9kg00qf 3566 12 most most RBS cord-022526-j9kg00qf 3566 13 sensitive sensitive JJ cord-022526-j9kg00qf 3566 14 and and CC cord-022526-j9kg00qf 3566 15 rapid rapid JJ cord-022526-j9kg00qf 3566 16 test test NN cord-022526-j9kg00qf 3566 17 for for IN cord-022526-j9kg00qf 3566 18 detecting detect VBG cord-022526-j9kg00qf 3566 19 Salmonella Salmonella NNP cord-022526-j9kg00qf 3566 20 in in IN cord-022526-j9kg00qf 3566 21 feces fece NNS cord-022526-j9kg00qf 3566 22 . . . cord-022526-j9kg00qf 3567 1 A a DT cord-022526-j9kg00qf 3567 2 single single JJ cord-022526-j9kg00qf 3567 3 PCR PCR NNP cord-022526-j9kg00qf 3567 4 test test NN cord-022526-j9kg00qf 3567 5 applied apply VBD cord-022526-j9kg00qf 3567 6 early early RB cord-022526-j9kg00qf 3567 7 in in IN cord-022526-j9kg00qf 3567 8 the the DT cord-022526-j9kg00qf 3567 9 course course NN cord-022526-j9kg00qf 3567 10 of of IN cord-022526-j9kg00qf 3567 11 disease disease NN cord-022526-j9kg00qf 3567 12 is be VBZ cord-022526-j9kg00qf 3567 13 a a DT cord-022526-j9kg00qf 3567 14 more more RBR cord-022526-j9kg00qf 3567 15 sensitive sensitive JJ cord-022526-j9kg00qf 3567 16 test test NN cord-022526-j9kg00qf 3567 17 for for IN cord-022526-j9kg00qf 3567 18 the the DT cord-022526-j9kg00qf 3567 19 presence presence NN cord-022526-j9kg00qf 3567 20 of of IN cord-022526-j9kg00qf 3567 21 Salmonella Salmonella NNP cord-022526-j9kg00qf 3567 22 than than IN cord-022526-j9kg00qf 3567 23 repeated repeat VBN cord-022526-j9kg00qf 3567 24 fecal fecal JJ cord-022526-j9kg00qf 3567 25 cultures culture NNS cord-022526-j9kg00qf 3567 26 . . . cord-022526-j9kg00qf 3568 1 46 46 CD cord-022526-j9kg00qf 3568 2 , , , cord-022526-j9kg00qf 3568 3 47 47 CD cord-022526-j9kg00qf 3568 4 Detection detection NN cord-022526-j9kg00qf 3568 5 of of IN cord-022526-j9kg00qf 3568 6 salmonellae salmonella NNS cord-022526-j9kg00qf 3568 7 in in IN cord-022526-j9kg00qf 3568 8 feces fece NNS cord-022526-j9kg00qf 3568 9 does do VBZ cord-022526-j9kg00qf 3568 10 not not RB cord-022526-j9kg00qf 3568 11 prove prove VB cord-022526-j9kg00qf 3568 12 a a DT cord-022526-j9kg00qf 3568 13 diagnosis diagnosis NN cord-022526-j9kg00qf 3568 14 of of IN cord-022526-j9kg00qf 3568 15 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3568 16 , , , cord-022526-j9kg00qf 3568 17 but but CC cord-022526-j9kg00qf 3568 18 the the DT cord-022526-j9kg00qf 3568 19 positive positive JJ cord-022526-j9kg00qf 3568 20 predictive predictive JJ cord-022526-j9kg00qf 3568 21 value value NN cord-022526-j9kg00qf 3568 22 of of IN cord-022526-j9kg00qf 3568 23 a a DT cord-022526-j9kg00qf 3568 24 positive positive JJ cord-022526-j9kg00qf 3568 25 PCR pcr NN cord-022526-j9kg00qf 3568 26 or or CC cord-022526-j9kg00qf 3568 27 culture culture NN cord-022526-j9kg00qf 3568 28 results result NNS cord-022526-j9kg00qf 3568 29 is be VBZ cord-022526-j9kg00qf 3568 30 high high JJ cord-022526-j9kg00qf 3568 31 in in IN cord-022526-j9kg00qf 3568 32 horses horse NNS cord-022526-j9kg00qf 3568 33 with with IN cord-022526-j9kg00qf 3568 34 compatible compatible JJ cord-022526-j9kg00qf 3568 35 clinical clinical JJ cord-022526-j9kg00qf 3568 36 signs sign NNS cord-022526-j9kg00qf 3568 37 . . . cord-022526-j9kg00qf 3569 1 Culture culture NN cord-022526-j9kg00qf 3569 2 of of IN cord-022526-j9kg00qf 3569 3 peripheral peripheral JJ cord-022526-j9kg00qf 3569 4 blood blood NN cord-022526-j9kg00qf 3569 5 may may MD cord-022526-j9kg00qf 3569 6 allow allow VB cord-022526-j9kg00qf 3569 7 isolation isolation NN cord-022526-j9kg00qf 3569 8 of of IN cord-022526-j9kg00qf 3569 9 the the DT cord-022526-j9kg00qf 3569 10 organism organism NN cord-022526-j9kg00qf 3569 11 if if IN cord-022526-j9kg00qf 3569 12 bacteremia bacteremia NN cord-022526-j9kg00qf 3569 13 or or CC cord-022526-j9kg00qf 3569 14 septicemia septicemia NN cord-022526-j9kg00qf 3569 15 is be VBZ cord-022526-j9kg00qf 3569 16 present present JJ cord-022526-j9kg00qf 3569 17 , , , cord-022526-j9kg00qf 3569 18 but but CC cord-022526-j9kg00qf 3569 19 blood blood NN cord-022526-j9kg00qf 3569 20 cultures culture NNS cord-022526-j9kg00qf 3569 21 are be VBP cord-022526-j9kg00qf 3569 22 not not RB cord-022526-j9kg00qf 3569 23 a a DT cord-022526-j9kg00qf 3569 24 sensitive sensitive JJ cord-022526-j9kg00qf 3569 25 test test NN cord-022526-j9kg00qf 3569 26 for for IN cord-022526-j9kg00qf 3569 27 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3569 28 in in IN cord-022526-j9kg00qf 3569 29 adult adult NN cord-022526-j9kg00qf 3569 30 horses horse NNS cord-022526-j9kg00qf 3569 31 . . . cord-022526-j9kg00qf 3570 1 Although although IN cord-022526-j9kg00qf 3570 2 foals foal NNS cord-022526-j9kg00qf 3570 3 are be VBP cord-022526-j9kg00qf 3570 4 more more RBR cord-022526-j9kg00qf 3570 5 likely likely JJ cord-022526-j9kg00qf 3570 6 than than IN cord-022526-j9kg00qf 3570 7 adults adult NNS cord-022526-j9kg00qf 3570 8 to to TO cord-022526-j9kg00qf 3570 9 become become VB cord-022526-j9kg00qf 3570 10 septicemic septicemic JJ cord-022526-j9kg00qf 3570 11 , , , cord-022526-j9kg00qf 3570 12 culture culture NN cord-022526-j9kg00qf 3570 13 of of IN cord-022526-j9kg00qf 3570 14 blood blood NN cord-022526-j9kg00qf 3570 15 is be VBZ cord-022526-j9kg00qf 3570 16 recommended recommend VBN cord-022526-j9kg00qf 3570 17 in in IN cord-022526-j9kg00qf 3570 18 all all DT cord-022526-j9kg00qf 3570 19 cases case NNS cord-022526-j9kg00qf 3570 20 with with IN cord-022526-j9kg00qf 3570 21 signs sign NNS cord-022526-j9kg00qf 3570 22 suggestive suggestive JJ cord-022526-j9kg00qf 3570 23 of of IN cord-022526-j9kg00qf 3570 24 septicemia septicemia NN cord-022526-j9kg00qf 3570 25 . . . cord-022526-j9kg00qf 3571 1 Increased increase VBN cord-022526-j9kg00qf 3571 2 numbers number NNS cord-022526-j9kg00qf 3571 3 of of IN cord-022526-j9kg00qf 3571 4 fecal fecal JJ cord-022526-j9kg00qf 3571 5 leukocytes leukocyte NNS cord-022526-j9kg00qf 3571 6 suggest suggest VBP cord-022526-j9kg00qf 3571 7 an an DT cord-022526-j9kg00qf 3571 8 invasive invasive JJ cord-022526-j9kg00qf 3571 9 process process NN cord-022526-j9kg00qf 3571 10 in in IN cord-022526-j9kg00qf 3571 11 the the DT cord-022526-j9kg00qf 3571 12 colon colon NN cord-022526-j9kg00qf 3571 13 but but CC cord-022526-j9kg00qf 3571 14 are be VBP cord-022526-j9kg00qf 3571 15 not not RB cord-022526-j9kg00qf 3571 16 specific specific JJ cord-022526-j9kg00qf 3571 17 for for IN cord-022526-j9kg00qf 3571 18 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3571 19 . . . cord-022526-j9kg00qf 3572 1 Early early RB cord-022526-j9kg00qf 3572 2 in in IN cord-022526-j9kg00qf 3572 3 the the DT cord-022526-j9kg00qf 3572 4 course course NN cord-022526-j9kg00qf 3572 5 of of IN cord-022526-j9kg00qf 3572 6 the the DT cord-022526-j9kg00qf 3572 7 disease disease NN cord-022526-j9kg00qf 3572 8 , , , cord-022526-j9kg00qf 3572 9 dehydration dehydration NN cord-022526-j9kg00qf 3572 10 , , , cord-022526-j9kg00qf 3572 11 electrolyte electrolyte NN cord-022526-j9kg00qf 3572 12 and and CC cord-022526-j9kg00qf 3572 13 acid acid NN cord-022526-j9kg00qf 3572 14 - - HYPH cord-022526-j9kg00qf 3572 15 base base NN cord-022526-j9kg00qf 3572 16 imbalances imbalance NNS cord-022526-j9kg00qf 3572 17 , , , cord-022526-j9kg00qf 3572 18 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3572 19 , , , cord-022526-j9kg00qf 3572 20 and and CC cord-022526-j9kg00qf 3572 21 sepsis sepsis NN cord-022526-j9kg00qf 3572 22 may may MD cord-022526-j9kg00qf 3572 23 be be VB cord-022526-j9kg00qf 3572 24 life life NN cord-022526-j9kg00qf 3572 25 threatening threaten VBG cord-022526-j9kg00qf 3572 26 . . . cord-022526-j9kg00qf 3573 1 Aggressive aggressive JJ cord-022526-j9kg00qf 3573 2 treatment treatment NN cord-022526-j9kg00qf 3573 3 during during IN cord-022526-j9kg00qf 3573 4 the the DT cord-022526-j9kg00qf 3573 5 acute acute JJ cord-022526-j9kg00qf 3573 6 stages stage NNS cord-022526-j9kg00qf 3573 7 to to TO cord-022526-j9kg00qf 3573 8 replace replace VB cord-022526-j9kg00qf 3573 9 fluids fluid NNS cord-022526-j9kg00qf 3573 10 lost lose VBN cord-022526-j9kg00qf 3573 11 in in IN cord-022526-j9kg00qf 3573 12 the the DT cord-022526-j9kg00qf 3573 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3573 14 and and CC cord-022526-j9kg00qf 3573 15 to to TO cord-022526-j9kg00qf 3573 16 control control VB cord-022526-j9kg00qf 3573 17 sepsis sepsis NN cord-022526-j9kg00qf 3573 18 and and CC cord-022526-j9kg00qf 3573 19 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3573 20 is be VBZ cord-022526-j9kg00qf 3573 21 often often RB cord-022526-j9kg00qf 3573 22 effective effective JJ cord-022526-j9kg00qf 3573 23 in in IN cord-022526-j9kg00qf 3573 24 controlling control VBG cord-022526-j9kg00qf 3573 25 the the DT cord-022526-j9kg00qf 3573 26 primary primary JJ cord-022526-j9kg00qf 3573 27 disease disease NN cord-022526-j9kg00qf 3573 28 . . . cord-022526-j9kg00qf 3574 1 Weight weight NN cord-022526-j9kg00qf 3574 2 loss loss NN cord-022526-j9kg00qf 3574 3 and and CC cord-022526-j9kg00qf 3574 4 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 3574 5 are be VBP cord-022526-j9kg00qf 3574 6 often often RB cord-022526-j9kg00qf 3574 7 severe severe JJ cord-022526-j9kg00qf 3574 8 . . . cord-022526-j9kg00qf 3575 1 Complications complication NNS cord-022526-j9kg00qf 3575 2 such such JJ cord-022526-j9kg00qf 3575 3 as as IN cord-022526-j9kg00qf 3575 4 multiorgan multiorgan NNP cord-022526-j9kg00qf 3575 5 dysfunction dysfunction NN cord-022526-j9kg00qf 3575 6 , , , cord-022526-j9kg00qf 3575 7 vascular vascular JJ cord-022526-j9kg00qf 3575 8 leak leak NN cord-022526-j9kg00qf 3575 9 syndrome syndrome NN cord-022526-j9kg00qf 3575 10 with with IN cord-022526-j9kg00qf 3575 11 peripheral peripheral JJ cord-022526-j9kg00qf 3575 12 and and CC cord-022526-j9kg00qf 3575 13 organ organ NN cord-022526-j9kg00qf 3575 14 edema edema NN cord-022526-j9kg00qf 3575 15 , , , cord-022526-j9kg00qf 3575 16 laminitis laminitis NN cord-022526-j9kg00qf 3575 17 , , , cord-022526-j9kg00qf 3575 18 acute acute JJ cord-022526-j9kg00qf 3575 19 renal renal JJ cord-022526-j9kg00qf 3575 20 failure failure NN cord-022526-j9kg00qf 3575 21 , , , cord-022526-j9kg00qf 3575 22 venous venous JJ cord-022526-j9kg00qf 3575 23 thrombosis thrombosis NN cord-022526-j9kg00qf 3575 24 and and CC cord-022526-j9kg00qf 3575 25 septic septic JJ cord-022526-j9kg00qf 3575 26 phlebitis phlebitis NN cord-022526-j9kg00qf 3575 27 , , , cord-022526-j9kg00qf 3575 28 irreversible irreversible JJ cord-022526-j9kg00qf 3575 29 protein protein NN cord-022526-j9kg00qf 3575 30 - - HYPH cord-022526-j9kg00qf 3575 31 losing lose VBG cord-022526-j9kg00qf 3575 32 enteropathy enteropathy NNS cord-022526-j9kg00qf 3575 33 or or CC cord-022526-j9kg00qf 3575 34 chronic chronic JJ cord-022526-j9kg00qf 3575 35 malabsorption malabsorption NN cord-022526-j9kg00qf 3575 36 , , , cord-022526-j9kg00qf 3575 37 pulmonary pulmonary JJ cord-022526-j9kg00qf 3575 38 aspergillosis aspergillosis NN cord-022526-j9kg00qf 3575 39 , , , cord-022526-j9kg00qf 3575 40 and and CC cord-022526-j9kg00qf 3575 41 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3575 42 infarction infarction NN cord-022526-j9kg00qf 3575 43 can can MD cord-022526-j9kg00qf 3575 44 occur occur VB cord-022526-j9kg00qf 3575 45 . . . cord-022526-j9kg00qf 3576 1 In in IN cord-022526-j9kg00qf 3576 2 many many JJ cord-022526-j9kg00qf 3576 3 instances instance NNS cord-022526-j9kg00qf 3576 4 , , , cord-022526-j9kg00qf 3576 5 horses horse NNS cord-022526-j9kg00qf 3576 6 recover recover VBP cord-022526-j9kg00qf 3576 7 from from IN cord-022526-j9kg00qf 3576 8 acute acute JJ cord-022526-j9kg00qf 3576 9 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3576 10 with with IN cord-022526-j9kg00qf 3576 11 aggressive aggressive JJ cord-022526-j9kg00qf 3576 12 treatment treatment NN cord-022526-j9kg00qf 3576 13 , , , cord-022526-j9kg00qf 3576 14 only only RB cord-022526-j9kg00qf 3576 15 to to TO cord-022526-j9kg00qf 3576 16 succumb succumb VB cord-022526-j9kg00qf 3576 17 to to IN cord-022526-j9kg00qf 3576 18 complications complication NNS cord-022526-j9kg00qf 3576 19 of of IN cord-022526-j9kg00qf 3576 20 the the DT cord-022526-j9kg00qf 3576 21 disease disease NN cord-022526-j9kg00qf 3576 22 , , , cord-022526-j9kg00qf 3576 23 partially partially RB cord-022526-j9kg00qf 3576 24 explaining explain VBG cord-022526-j9kg00qf 3576 25 the the DT cord-022526-j9kg00qf 3576 26 high high JJ cord-022526-j9kg00qf 3576 27 fatality fatality NN cord-022526-j9kg00qf 3576 28 rate rate NN cord-022526-j9kg00qf 3576 29 of of IN cord-022526-j9kg00qf 3576 30 equine equine JJ cord-022526-j9kg00qf 3576 31 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3576 32 compared compare VBN cord-022526-j9kg00qf 3576 33 with with IN cord-022526-j9kg00qf 3576 34 human human JJ cord-022526-j9kg00qf 3576 35 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3576 36 . . . cord-022526-j9kg00qf 3577 1 Chronic chronic JJ cord-022526-j9kg00qf 3577 2 , , , cord-022526-j9kg00qf 3577 3 mild mild JJ cord-022526-j9kg00qf 3577 4 to to IN cord-022526-j9kg00qf 3577 5 moderate moderate JJ cord-022526-j9kg00qf 3577 6 diarrhea diarrhea NN cord-022526-j9kg00qf 3577 7 occasionally occasionally RB cord-022526-j9kg00qf 3577 8 occurs occur VBZ cord-022526-j9kg00qf 3577 9 in in IN cord-022526-j9kg00qf 3577 10 horses horse NNS cord-022526-j9kg00qf 3577 11 after after IN cord-022526-j9kg00qf 3577 12 a a DT cord-022526-j9kg00qf 3577 13 bout bout NN cord-022526-j9kg00qf 3577 14 of of IN cord-022526-j9kg00qf 3577 15 severe severe JJ cord-022526-j9kg00qf 3577 16 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3577 17 , , , cord-022526-j9kg00qf 3577 18 usually usually RB cord-022526-j9kg00qf 3577 19 with with IN cord-022526-j9kg00qf 3577 20 protein protein NN cord-022526-j9kg00qf 3577 21 - - HYPH cord-022526-j9kg00qf 3577 22 losing lose VBG cord-022526-j9kg00qf 3577 23 enteropathy enteropathy NNP cord-022526-j9kg00qf 3577 24 . . . cord-022526-j9kg00qf 3578 1 If if IN cord-022526-j9kg00qf 3578 2 the the DT cord-022526-j9kg00qf 3578 3 chronic chronic JJ cord-022526-j9kg00qf 3578 4 diarrhea diarrhea NN cord-022526-j9kg00qf 3578 5 persists persist VBZ cord-022526-j9kg00qf 3578 6 beyond beyond IN cord-022526-j9kg00qf 3578 7 4 4 CD cord-022526-j9kg00qf 3578 8 to to TO cord-022526-j9kg00qf 3578 9 5 5 CD cord-022526-j9kg00qf 3578 10 weeks week NNS cord-022526-j9kg00qf 3578 11 after after IN cord-022526-j9kg00qf 3578 12 the the DT cord-022526-j9kg00qf 3578 13 onset onset NN cord-022526-j9kg00qf 3578 14 of of IN cord-022526-j9kg00qf 3578 15 signs sign NNS cord-022526-j9kg00qf 3578 16 , , , cord-022526-j9kg00qf 3578 17 the the DT cord-022526-j9kg00qf 3578 18 prognosis prognosis NN cord-022526-j9kg00qf 3578 19 for for IN cord-022526-j9kg00qf 3578 20 recovery recovery NN cord-022526-j9kg00qf 3578 21 is be VBZ cord-022526-j9kg00qf 3578 22 poor poor JJ cord-022526-j9kg00qf 3578 23 . . . cord-022526-j9kg00qf 3579 1 15 15 CD cord-022526-j9kg00qf 3579 2 Potomac Potomac NNP cord-022526-j9kg00qf 3579 3 horse horse NN cord-022526-j9kg00qf 3579 4 fever fever NN cord-022526-j9kg00qf 3579 5 ( ( -LRB- cord-022526-j9kg00qf 3579 6 equine equine JJ cord-022526-j9kg00qf 3579 7 monocytic monocytic JJ cord-022526-j9kg00qf 3579 8 ehrlichiosis ehrlichiosis NNP cord-022526-j9kg00qf 3579 9 ) ) -RRB- cord-022526-j9kg00qf 3579 10 is be VBZ cord-022526-j9kg00qf 3579 11 caused cause VBN cord-022526-j9kg00qf 3579 12 by by IN cord-022526-j9kg00qf 3579 13 the the DT cord-022526-j9kg00qf 3579 14 obligate obligate JJ cord-022526-j9kg00qf 3579 15 intracellular intracellular JJ cord-022526-j9kg00qf 3579 16 rickettsial rickettsial JJ cord-022526-j9kg00qf 3579 17 organism organism NN cord-022526-j9kg00qf 3579 18 Neorickettsia Neorickettsia NNP cord-022526-j9kg00qf 3579 19 risticii risticii NN cord-022526-j9kg00qf 3579 20 . . . cord-022526-j9kg00qf 3580 1 [ [ -LRB- cord-022526-j9kg00qf 3580 2 48 48 CD cord-022526-j9kg00qf 3580 3 ] ] -RRB- cord-022526-j9kg00qf 3580 4 [ [ -LRB- cord-022526-j9kg00qf 3580 5 49 49 CD cord-022526-j9kg00qf 3580 6 ] ] -RRB- cord-022526-j9kg00qf 3580 7 [ [ -LRB- cord-022526-j9kg00qf 3580 8 50 50 CD cord-022526-j9kg00qf 3580 9 ] ] -RRB- cord-022526-j9kg00qf 3581 1 [ [ -LRB- cord-022526-j9kg00qf 3581 2 51 51 CD cord-022526-j9kg00qf 3581 3 ] ] -RRB- cord-022526-j9kg00qf 3582 1 The the DT cord-022526-j9kg00qf 3582 2 disease disease NN cord-022526-j9kg00qf 3582 3 is be VBZ cord-022526-j9kg00qf 3582 4 most most RBS cord-022526-j9kg00qf 3582 5 common common JJ cord-022526-j9kg00qf 3582 6 from from IN cord-022526-j9kg00qf 3582 7 late late JJ cord-022526-j9kg00qf 3582 8 summer summer NN cord-022526-j9kg00qf 3582 9 to to IN cord-022526-j9kg00qf 3582 10 early early JJ cord-022526-j9kg00qf 3582 11 fall fall NN cord-022526-j9kg00qf 3582 12 , , , cord-022526-j9kg00qf 3582 13 with with IN cord-022526-j9kg00qf 3582 14 a a DT cord-022526-j9kg00qf 3582 15 peak peak NN cord-022526-j9kg00qf 3582 16 incidence incidence NN cord-022526-j9kg00qf 3582 17 in in IN cord-022526-j9kg00qf 3582 18 July July NNP cord-022526-j9kg00qf 3582 19 and and CC cord-022526-j9kg00qf 3582 20 August August NNP cord-022526-j9kg00qf 3582 21 . . . cord-022526-j9kg00qf 3583 1 Potomac Potomac NNP cord-022526-j9kg00qf 3583 2 horse horse NN cord-022526-j9kg00qf 3583 3 fever fever NN cord-022526-j9kg00qf 3583 4 was be VBD cord-022526-j9kg00qf 3583 5 described describe VBN cord-022526-j9kg00qf 3583 6 first first RB cord-022526-j9kg00qf 3583 7 in in IN cord-022526-j9kg00qf 3583 8 the the DT cord-022526-j9kg00qf 3583 9 Northeast Northeast NNP cord-022526-j9kg00qf 3583 10 but but CC cord-022526-j9kg00qf 3583 11 since since IN cord-022526-j9kg00qf 3583 12 has have VBZ cord-022526-j9kg00qf 3583 13 been be VBN cord-022526-j9kg00qf 3583 14 diagnosed diagnose VBN cord-022526-j9kg00qf 3583 15 in in IN cord-022526-j9kg00qf 3583 16 most most JJS cord-022526-j9kg00qf 3583 17 areas area NNS cord-022526-j9kg00qf 3583 18 of of IN cord-022526-j9kg00qf 3583 19 the the DT cord-022526-j9kg00qf 3583 20 continental continental JJ cord-022526-j9kg00qf 3583 21 United United NNP cord-022526-j9kg00qf 3583 22 States States NNP cord-022526-j9kg00qf 3583 23 , , , cord-022526-j9kg00qf 3583 24 with with IN cord-022526-j9kg00qf 3583 25 a a DT cord-022526-j9kg00qf 3583 26 particularly particularly RB cord-022526-j9kg00qf 3583 27 high high JJ cord-022526-j9kg00qf 3583 28 prevalence prevalence NN cord-022526-j9kg00qf 3583 29 in in IN cord-022526-j9kg00qf 3583 30 the the DT cord-022526-j9kg00qf 3583 31 Northeast Northeast NNP cord-022526-j9kg00qf 3583 32 and and CC cord-022526-j9kg00qf 3583 33 Midwest Midwest NNP cord-022526-j9kg00qf 3583 34 . . . cord-022526-j9kg00qf 3584 1 The the DT cord-022526-j9kg00qf 3584 2 geographic geographic JJ cord-022526-j9kg00qf 3584 3 distribution distribution NN cord-022526-j9kg00qf 3584 4 is be VBZ cord-022526-j9kg00qf 3584 5 characterized characterize VBN cord-022526-j9kg00qf 3584 6 by by IN cord-022526-j9kg00qf 3584 7 a a DT cord-022526-j9kg00qf 3584 8 significantly significantly RB cord-022526-j9kg00qf 3584 9 higher high JJR cord-022526-j9kg00qf 3584 10 percentage percentage NN cord-022526-j9kg00qf 3584 11 of of IN cord-022526-j9kg00qf 3584 12 cases case NNS cord-022526-j9kg00qf 3584 13 found find VBN cord-022526-j9kg00qf 3584 14 along along IN cord-022526-j9kg00qf 3584 15 waterways waterway NNS cord-022526-j9kg00qf 3584 16 and and CC cord-022526-j9kg00qf 3584 17 rivers river NNS cord-022526-j9kg00qf 3584 18 . . . cord-022526-j9kg00qf 3585 1 48 48 CD cord-022526-j9kg00qf 3585 2 , , , cord-022526-j9kg00qf 3585 3 49 49 CD cord-022526-j9kg00qf 3586 1 The the DT cord-022526-j9kg00qf 3586 2 disease disease NN cord-022526-j9kg00qf 3586 3 occurs occur VBZ cord-022526-j9kg00qf 3586 4 sporadically sporadically RB cord-022526-j9kg00qf 3586 5 , , , cord-022526-j9kg00qf 3586 6 temporally temporally RB cord-022526-j9kg00qf 3586 7 and and CC cord-022526-j9kg00qf 3586 8 geographically geographically RB cord-022526-j9kg00qf 3586 9 , , , cord-022526-j9kg00qf 3586 10 and and CC cord-022526-j9kg00qf 3586 11 can can MD cord-022526-j9kg00qf 3586 12 affect affect VB cord-022526-j9kg00qf 3586 13 any any DT cord-022526-j9kg00qf 3586 14 age age NN cord-022526-j9kg00qf 3586 15 group group NN cord-022526-j9kg00qf 3586 16 of of IN cord-022526-j9kg00qf 3586 17 horses horse NNS cord-022526-j9kg00qf 3586 18 . . . cord-022526-j9kg00qf 3587 1 The the DT cord-022526-j9kg00qf 3587 2 case case NN cord-022526-j9kg00qf 3587 3 fatality fatality NN cord-022526-j9kg00qf 3587 4 rate rate NN cord-022526-j9kg00qf 3587 5 is be VBZ cord-022526-j9kg00qf 3587 6 5 5 CD cord-022526-j9kg00qf 3587 7 % % NN cord-022526-j9kg00qf 3587 8 to to TO cord-022526-j9kg00qf 3587 9 30 30 CD cord-022526-j9kg00qf 3587 10 % % NN cord-022526-j9kg00qf 3587 11 . . . cord-022526-j9kg00qf 3588 1 48 48 CD cord-022526-j9kg00qf 3589 1 Transmission transmission NN cord-022526-j9kg00qf 3589 2 of of IN cord-022526-j9kg00qf 3589 3 N. N. NNP cord-022526-j9kg00qf 3589 4 risticii risticii NNP cord-022526-j9kg00qf 3589 5 has have VBZ cord-022526-j9kg00qf 3589 6 been be VBN cord-022526-j9kg00qf 3589 7 reproduced reproduce VBN cord-022526-j9kg00qf 3589 8 experimentally experimentally RB cord-022526-j9kg00qf 3589 9 by by IN cord-022526-j9kg00qf 3589 10 oral oral JJ cord-022526-j9kg00qf 3589 11 , , , cord-022526-j9kg00qf 3589 12 intramuscular intramuscular JJ cord-022526-j9kg00qf 3589 13 , , , cord-022526-j9kg00qf 3589 14 intradermal intradermal JJ cord-022526-j9kg00qf 3589 15 , , , cord-022526-j9kg00qf 3589 16 subcutaneous subcutaneous JJ cord-022526-j9kg00qf 3589 17 , , , cord-022526-j9kg00qf 3589 18 and and CC cord-022526-j9kg00qf 3589 19 intravenous intravenous JJ cord-022526-j9kg00qf 3589 20 routes route NNS cord-022526-j9kg00qf 3589 21 . . . cord-022526-j9kg00qf 3590 1 48 48 CD cord-022526-j9kg00qf 3590 2 , , , cord-022526-j9kg00qf 3590 3 52 52 CD cord-022526-j9kg00qf 3591 1 However however RB cord-022526-j9kg00qf 3591 2 , , , cord-022526-j9kg00qf 3591 3 the the DT cord-022526-j9kg00qf 3591 4 natural natural JJ cord-022526-j9kg00qf 3591 5 route route NN cord-022526-j9kg00qf 3591 6 of of IN cord-022526-j9kg00qf 3591 7 infection infection NN cord-022526-j9kg00qf 3591 8 has have VBZ cord-022526-j9kg00qf 3591 9 remained remain VBN cord-022526-j9kg00qf 3591 10 a a DT cord-022526-j9kg00qf 3591 11 mystery mystery NN cord-022526-j9kg00qf 3591 12 until until IN cord-022526-j9kg00qf 3591 13 recently recently RB cord-022526-j9kg00qf 3591 14 . . . cord-022526-j9kg00qf 3592 1 The the DT cord-022526-j9kg00qf 3592 2 epidemiologic epidemiologic JJ cord-022526-j9kg00qf 3592 3 data datum NNS cord-022526-j9kg00qf 3592 4 , , , cord-022526-j9kg00qf 3592 5 the the DT cord-022526-j9kg00qf 3592 6 fact fact NN cord-022526-j9kg00qf 3592 7 that that IN cord-022526-j9kg00qf 3592 8 many many JJ cord-022526-j9kg00qf 3592 9 other other JJ cord-022526-j9kg00qf 3592 10 rickettsial rickettsial JJ cord-022526-j9kg00qf 3592 11 diseases disease NNS cord-022526-j9kg00qf 3592 12 are be VBP cord-022526-j9kg00qf 3592 13 transmitted transmit VBN cord-022526-j9kg00qf 3592 14 by by IN cord-022526-j9kg00qf 3592 15 insect insect NN cord-022526-j9kg00qf 3592 16 vectors vector NNS cord-022526-j9kg00qf 3592 17 , , , cord-022526-j9kg00qf 3592 18 and and CC cord-022526-j9kg00qf 3592 19 the the DT cord-022526-j9kg00qf 3592 20 finding finding NN cord-022526-j9kg00qf 3592 21 that that IN cord-022526-j9kg00qf 3592 22 the the DT cord-022526-j9kg00qf 3592 23 disease disease NN cord-022526-j9kg00qf 3592 24 can can MD cord-022526-j9kg00qf 3592 25 be be VB cord-022526-j9kg00qf 3592 26 transmitted transmit VBN cord-022526-j9kg00qf 3592 27 via via IN cord-022526-j9kg00qf 3592 28 whole whole JJ cord-022526-j9kg00qf 3592 29 blood blood NN cord-022526-j9kg00qf 3592 30 have have VBP cord-022526-j9kg00qf 3592 31 implicated implicate VBN cord-022526-j9kg00qf 3592 32 insect insect NN cord-022526-j9kg00qf 3592 33 vectors vector NNS cord-022526-j9kg00qf 3592 34 in in IN cord-022526-j9kg00qf 3592 35 the the DT cord-022526-j9kg00qf 3592 36 natural natural JJ cord-022526-j9kg00qf 3592 37 transmission transmission NN cord-022526-j9kg00qf 3592 38 of of IN cord-022526-j9kg00qf 3592 39 the the DT cord-022526-j9kg00qf 3592 40 organism organism NN cord-022526-j9kg00qf 3592 41 . . . cord-022526-j9kg00qf 3593 1 Attempts attempt NNS cord-022526-j9kg00qf 3593 2 to to TO cord-022526-j9kg00qf 3593 3 transmit transmit VB cord-022526-j9kg00qf 3593 4 the the DT cord-022526-j9kg00qf 3593 5 disease disease NN cord-022526-j9kg00qf 3593 6 experimentally experimentally RB cord-022526-j9kg00qf 3593 7 with with IN cord-022526-j9kg00qf 3593 8 ticks tick NNS cord-022526-j9kg00qf 3593 9 ( ( -LRB- cord-022526-j9kg00qf 3593 10 Dermacentor Dermacentor NNP cord-022526-j9kg00qf 3593 11 variablis variablis NNP cord-022526-j9kg00qf 3593 12 ) ) -RRB- cord-022526-j9kg00qf 3593 13 or or CC cord-022526-j9kg00qf 3593 14 biting bite VBG cord-022526-j9kg00qf 3593 15 flies fly NNS cord-022526-j9kg00qf 3593 16 ( ( -LRB- cord-022526-j9kg00qf 3593 17 Stomoxys Stomoxys NNP cord-022526-j9kg00qf 3593 18 calcitrans calcitran NNS cord-022526-j9kg00qf 3593 19 ) ) -RRB- cord-022526-j9kg00qf 3593 20 have have VBP cord-022526-j9kg00qf 3593 21 been be VBN cord-022526-j9kg00qf 3593 22 unsuccessful unsuccessful JJ cord-022526-j9kg00qf 3593 23 . . . cord-022526-j9kg00qf 3594 1 53 53 CD cord-022526-j9kg00qf 3594 2 , , , cord-022526-j9kg00qf 3594 3 54 54 CD cord-022526-j9kg00qf 3595 1 Recently recently RB cord-022526-j9kg00qf 3595 2 , , , cord-022526-j9kg00qf 3595 3 N. N. NNP cord-022526-j9kg00qf 3595 4 risticii risticii NNP cord-022526-j9kg00qf 3595 5 has have VBZ cord-022526-j9kg00qf 3595 6 been be VBN cord-022526-j9kg00qf 3595 7 found find VBN cord-022526-j9kg00qf 3595 8 to to TO cord-022526-j9kg00qf 3595 9 infect infect VB cord-022526-j9kg00qf 3595 10 virgulate virgulate NN cord-022526-j9kg00qf 3595 11 cercariae cercaria NNS cord-022526-j9kg00qf 3595 12 larval larval JJ cord-022526-j9kg00qf 3595 13 stages stage NNS cord-022526-j9kg00qf 3595 14 of of IN cord-022526-j9kg00qf 3595 15 trematodes trematode NNS cord-022526-j9kg00qf 3595 16 that that WDT cord-022526-j9kg00qf 3595 17 use use VBP cord-022526-j9kg00qf 3595 18 operculate operculate JJ cord-022526-j9kg00qf 3595 19 freshwater freshwater JJ cord-022526-j9kg00qf 3595 20 snails snail NNS cord-022526-j9kg00qf 3595 21 ( ( -LRB- cord-022526-j9kg00qf 3595 22 Juga Juga NNP cord-022526-j9kg00qf 3595 23 spp spp NNS cord-022526-j9kg00qf 3595 24 . . . cord-022526-j9kg00qf 3595 25 ) ) -RRB- cord-022526-j9kg00qf 3596 1 as as IN cord-022526-j9kg00qf 3596 2 part part NN cord-022526-j9kg00qf 3596 3 of of IN cord-022526-j9kg00qf 3596 4 their -PRON- PRP$ cord-022526-j9kg00qf 3596 5 life life NN cord-022526-j9kg00qf 3596 6 cycle cycle NN cord-022526-j9kg00qf 3596 7 in in IN cord-022526-j9kg00qf 3596 8 northern northern JJ cord-022526-j9kg00qf 3596 9 California California NNP cord-022526-j9kg00qf 3596 10 . . . cord-022526-j9kg00qf 3597 1 55 55 CD cord-022526-j9kg00qf 3598 1 Infected infected JJ cord-022526-j9kg00qf 3598 2 virgulate virgulate NN cord-022526-j9kg00qf 3598 3 cercariae cercaria NNS cord-022526-j9kg00qf 3598 4 have have VBP cord-022526-j9kg00qf 3598 5 been be VBN cord-022526-j9kg00qf 3598 6 identified identify VBN cord-022526-j9kg00qf 3598 7 in in IN cord-022526-j9kg00qf 3598 8 aquatic aquatic JJ cord-022526-j9kg00qf 3598 9 snails snail NNS cord-022526-j9kg00qf 3598 10 collected collect VBN cord-022526-j9kg00qf 3598 11 in in IN cord-022526-j9kg00qf 3598 12 other other JJ cord-022526-j9kg00qf 3598 13 parts part NNS cord-022526-j9kg00qf 3598 14 of of IN cord-022526-j9kg00qf 3598 15 the the DT cord-022526-j9kg00qf 3598 16 country country NN cord-022526-j9kg00qf 3598 17 as as RB cord-022526-j9kg00qf 3598 18 well well RB cord-022526-j9kg00qf 3598 19 . . . cord-022526-j9kg00qf 3599 1 Virgulate Virgulate NNP cord-022526-j9kg00qf 3599 2 cercariae cercaria NNS cord-022526-j9kg00qf 3599 3 are be VBP cord-022526-j9kg00qf 3599 4 part part NN cord-022526-j9kg00qf 3599 5 of of IN cord-022526-j9kg00qf 3599 6 the the DT cord-022526-j9kg00qf 3599 7 life life NN cord-022526-j9kg00qf 3599 8 cycle cycle NN cord-022526-j9kg00qf 3599 9 of of IN cord-022526-j9kg00qf 3599 10 trematodes trematode NNS cord-022526-j9kg00qf 3599 11 that that WDT cord-022526-j9kg00qf 3599 12 are be VBP cord-022526-j9kg00qf 3599 13 common common JJ cord-022526-j9kg00qf 3599 14 parasites parasite NNS cord-022526-j9kg00qf 3599 15 of of IN cord-022526-j9kg00qf 3599 16 many many JJ cord-022526-j9kg00qf 3599 17 species specie NNS cord-022526-j9kg00qf 3599 18 and and CC cord-022526-j9kg00qf 3599 19 use use VB cord-022526-j9kg00qf 3599 20 freshwater freshwater JJ cord-022526-j9kg00qf 3599 21 snails snail NNS cord-022526-j9kg00qf 3599 22 and and CC cord-022526-j9kg00qf 3599 23 aquatic aquatic JJ cord-022526-j9kg00qf 3599 24 insects insect NNS cord-022526-j9kg00qf 3599 25 as as IN cord-022526-j9kg00qf 3599 26 intermediate intermediate JJ cord-022526-j9kg00qf 3599 27 hosts host NNS cord-022526-j9kg00qf 3599 28 . . . cord-022526-j9kg00qf 3600 1 Although although IN cord-022526-j9kg00qf 3600 2 the the DT cord-022526-j9kg00qf 3600 3 trematode trematode NN cord-022526-j9kg00qf 3600 4 species specie NNS cord-022526-j9kg00qf 3600 5 infected infect VBN cord-022526-j9kg00qf 3600 6 with with IN cord-022526-j9kg00qf 3600 7 N. N. NNP cord-022526-j9kg00qf 3600 8 risticii risticii NNP cord-022526-j9kg00qf 3600 9 remains remain VBZ cord-022526-j9kg00qf 3600 10 to to TO cord-022526-j9kg00qf 3600 11 be be VB cord-022526-j9kg00qf 3600 12 identified identify VBN cord-022526-j9kg00qf 3600 13 definitively definitively RB cord-022526-j9kg00qf 3600 14 , , , cord-022526-j9kg00qf 3600 15 at at RB cord-022526-j9kg00qf 3600 16 least least RBS cord-022526-j9kg00qf 3600 17 two two CD cord-022526-j9kg00qf 3600 18 species specie NNS cord-022526-j9kg00qf 3600 19 are be VBP cord-022526-j9kg00qf 3600 20 considered consider VBN cord-022526-j9kg00qf 3600 21 potential potential JJ cord-022526-j9kg00qf 3600 22 vectors vector NNS cord-022526-j9kg00qf 3600 23 . . . cord-022526-j9kg00qf 3601 1 52 52 CD cord-022526-j9kg00qf 3602 1 During during IN cord-022526-j9kg00qf 3602 2 the the DT cord-022526-j9kg00qf 3602 3 trematode trematode NN cord-022526-j9kg00qf 3602 4 life life NN cord-022526-j9kg00qf 3602 5 cycle cycle NN cord-022526-j9kg00qf 3602 6 , , , cord-022526-j9kg00qf 3602 7 aquatic aquatic JJ cord-022526-j9kg00qf 3602 8 snails snail NNS cord-022526-j9kg00qf 3602 9 release release VBP cord-022526-j9kg00qf 3602 10 large large JJ cord-022526-j9kg00qf 3602 11 numbers number NNS cord-022526-j9kg00qf 3602 12 of of IN cord-022526-j9kg00qf 3602 13 infected infected JJ cord-022526-j9kg00qf 3602 14 cercariae cercaria NNS cord-022526-j9kg00qf 3602 15 into into IN cord-022526-j9kg00qf 3602 16 water water NN cord-022526-j9kg00qf 3602 17 , , , cord-022526-j9kg00qf 3602 18 where where WRB cord-022526-j9kg00qf 3602 19 they -PRON- PRP cord-022526-j9kg00qf 3602 20 seek seek VBP cord-022526-j9kg00qf 3602 21 their -PRON- PRP$ cord-022526-j9kg00qf 3602 22 next next JJ cord-022526-j9kg00qf 3602 23 intermediate intermediate JJ cord-022526-j9kg00qf 3602 24 host host NN cord-022526-j9kg00qf 3602 25 . . . cord-022526-j9kg00qf 3603 1 Infected infected JJ cord-022526-j9kg00qf 3603 2 metacercaria metacercaria NNS cord-022526-j9kg00qf 3603 3 have have VBP cord-022526-j9kg00qf 3603 4 been be VBN cord-022526-j9kg00qf 3603 5 identified identify VBN cord-022526-j9kg00qf 3603 6 in in IN cord-022526-j9kg00qf 3603 7 a a DT cord-022526-j9kg00qf 3603 8 variety variety NN cord-022526-j9kg00qf 3603 9 of of IN cord-022526-j9kg00qf 3603 10 aquatic aquatic JJ cord-022526-j9kg00qf 3603 11 insects insect NNS cord-022526-j9kg00qf 3603 12 . . . cord-022526-j9kg00qf 3604 1 56 56 CD cord-022526-j9kg00qf 3604 2 Preliminary preliminary JJ cord-022526-j9kg00qf 3604 3 studies study NNS cord-022526-j9kg00qf 3604 4 suggest suggest VBP cord-022526-j9kg00qf 3604 5 that that IN cord-022526-j9kg00qf 3604 6 N. N. NNP cord-022526-j9kg00qf 3604 7 risticii risticii NN cord-022526-j9kg00qf 3604 8 in in IN cord-022526-j9kg00qf 3604 9 fact fact NN cord-022526-j9kg00qf 3604 10 may may MD cord-022526-j9kg00qf 3604 11 be be VB cord-022526-j9kg00qf 3604 12 transmitted transmit VBN cord-022526-j9kg00qf 3604 13 via via IN cord-022526-j9kg00qf 3604 14 ingestion ingestion NN cord-022526-j9kg00qf 3604 15 of of IN cord-022526-j9kg00qf 3604 16 mature mature JJ cord-022526-j9kg00qf 3604 17 caddis caddis NN cord-022526-j9kg00qf 3604 18 flies fly NNS cord-022526-j9kg00qf 3604 19 containing contain VBG cord-022526-j9kg00qf 3604 20 infected infect VBN cord-022526-j9kg00qf 3604 21 metacercariae metacercariae NN cord-022526-j9kg00qf 3604 22 . . . cord-022526-j9kg00qf 3605 1 57 57 CD cord-022526-j9kg00qf 3606 1 Possibly possibly RB cord-022526-j9kg00qf 3606 2 horses horse NNS cord-022526-j9kg00qf 3606 3 are be VBP cord-022526-j9kg00qf 3606 4 infected infect VBN cord-022526-j9kg00qf 3606 5 by by IN cord-022526-j9kg00qf 3606 6 drinking drink VBG cord-022526-j9kg00qf 3606 7 water water NN cord-022526-j9kg00qf 3606 8 containing contain VBG cord-022526-j9kg00qf 3606 9 infected infect VBN cord-022526-j9kg00qf 3606 10 cercaria cercaria NNP cord-022526-j9kg00qf 3606 11 released release VBN cord-022526-j9kg00qf 3606 12 from from IN cord-022526-j9kg00qf 3606 13 snails snail NNS cord-022526-j9kg00qf 3606 14 or or CC cord-022526-j9kg00qf 3606 15 by by IN cord-022526-j9kg00qf 3606 16 ingesting ingest VBG cord-022526-j9kg00qf 3606 17 infected infect VBN cord-022526-j9kg00qf 3606 18 metacercariae metacercariae NN cord-022526-j9kg00qf 3606 19 in in IN cord-022526-j9kg00qf 3606 20 other other JJ cord-022526-j9kg00qf 3606 21 aquatic aquatic JJ cord-022526-j9kg00qf 3606 22 insects insect NNS cord-022526-j9kg00qf 3606 23 . . . cord-022526-j9kg00qf 3607 1 52 52 CD cord-022526-j9kg00qf 3608 1 The the DT cord-022526-j9kg00qf 3608 2 number number NN cord-022526-j9kg00qf 3608 3 of of IN cord-022526-j9kg00qf 3608 4 PCR pcr NN cord-022526-j9kg00qf 3608 5 - - HYPH cord-022526-j9kg00qf 3608 6 positive positive JJ cord-022526-j9kg00qf 3608 7 snails snail NNS cord-022526-j9kg00qf 3608 8 in in IN cord-022526-j9kg00qf 3608 9 endemic endemic JJ cord-022526-j9kg00qf 3608 10 regions region NNS cord-022526-j9kg00qf 3608 11 corresponds correspond VBZ cord-022526-j9kg00qf 3608 12 to to IN cord-022526-j9kg00qf 3608 13 the the DT cord-022526-j9kg00qf 3608 14 seasonal seasonal JJ cord-022526-j9kg00qf 3608 15 incidence incidence NN cord-022526-j9kg00qf 3608 16 of of IN cord-022526-j9kg00qf 3608 17 Potomac Potomac NNP cord-022526-j9kg00qf 3608 18 horse horse NN cord-022526-j9kg00qf 3608 19 fever fever NN cord-022526-j9kg00qf 3608 20 and and CC cord-022526-j9kg00qf 3608 21 may may MD cord-022526-j9kg00qf 3608 22 be be VB cord-022526-j9kg00qf 3608 23 as as RB cord-022526-j9kg00qf 3608 24 high high JJ cord-022526-j9kg00qf 3608 25 as as IN cord-022526-j9kg00qf 3608 26 26 26 CD cord-022526-j9kg00qf 3608 27 % % NN cord-022526-j9kg00qf 3608 28 . . . cord-022526-j9kg00qf 3609 1 58 58 CD cord-022526-j9kg00qf 3610 1 The the DT cord-022526-j9kg00qf 3610 2 pathogenesis pathogenesis NN cord-022526-j9kg00qf 3610 3 of of IN cord-022526-j9kg00qf 3610 4 N. n. NN cord-022526-j9kg00qf 3610 5 risticii risticii NN cord-022526-j9kg00qf 3610 6 is be VBZ cord-022526-j9kg00qf 3610 7 not not RB cord-022526-j9kg00qf 3610 8 understood understand VBN cord-022526-j9kg00qf 3610 9 completely completely RB cord-022526-j9kg00qf 3610 10 . . . cord-022526-j9kg00qf 3611 1 The the DT cord-022526-j9kg00qf 3611 2 organism organism NN cord-022526-j9kg00qf 3611 3 infects infect VBZ cord-022526-j9kg00qf 3611 4 and and CC cord-022526-j9kg00qf 3611 5 survives survive VBZ cord-022526-j9kg00qf 3611 6 in in IN cord-022526-j9kg00qf 3611 7 monocytes monocyte NNS cord-022526-j9kg00qf 3611 8 and and CC cord-022526-j9kg00qf 3611 9 monocyte monocyte NN cord-022526-j9kg00qf 3611 10 - - HYPH cord-022526-j9kg00qf 3611 11 derived derive VBN cord-022526-j9kg00qf 3611 12 leukocytes leukocyte NNS cord-022526-j9kg00qf 3611 13 and and CC cord-022526-j9kg00qf 3611 14 can can MD cord-022526-j9kg00qf 3611 15 be be VB cord-022526-j9kg00qf 3611 16 found find VBN cord-022526-j9kg00qf 3611 17 in in IN cord-022526-j9kg00qf 3611 18 blood blood NN cord-022526-j9kg00qf 3611 19 monocytes monocyte NNS cord-022526-j9kg00qf 3611 20 during during IN cord-022526-j9kg00qf 3611 21 natural natural JJ cord-022526-j9kg00qf 3611 22 infections infection NNS cord-022526-j9kg00qf 3611 23 , , , cord-022526-j9kg00qf 3611 24 but but CC cord-022526-j9kg00qf 3611 25 the the DT cord-022526-j9kg00qf 3611 26 sequence sequence NN cord-022526-j9kg00qf 3611 27 of of IN cord-022526-j9kg00qf 3611 28 events event NNS cord-022526-j9kg00qf 3611 29 resulting result VBG cord-022526-j9kg00qf 3611 30 in in IN cord-022526-j9kg00qf 3611 31 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3611 32 remains remain VBZ cord-022526-j9kg00qf 3611 33 speculative speculative JJ cord-022526-j9kg00qf 3611 34 . . . cord-022526-j9kg00qf 3612 1 The the DT cord-022526-j9kg00qf 3612 2 organism organism NN cord-022526-j9kg00qf 3612 3 appears appear VBZ cord-022526-j9kg00qf 3612 4 first first RB cord-022526-j9kg00qf 3612 5 to to TO cord-022526-j9kg00qf 3612 6 infect infect VB cord-022526-j9kg00qf 3612 7 blood blood NN cord-022526-j9kg00qf 3612 8 monocytes monocyte NNS cord-022526-j9kg00qf 3612 9 in in IN cord-022526-j9kg00qf 3612 10 experimentally experimentally RB cord-022526-j9kg00qf 3612 11 infected infect VBN cord-022526-j9kg00qf 3612 12 horses horse NNS cord-022526-j9kg00qf 3612 13 , , , cord-022526-j9kg00qf 3612 14 which which WDT cord-022526-j9kg00qf 3612 15 may may MD cord-022526-j9kg00qf 3612 16 be be VB cord-022526-j9kg00qf 3612 17 the the DT cord-022526-j9kg00qf 3612 18 vehicle vehicle NN cord-022526-j9kg00qf 3612 19 of of IN cord-022526-j9kg00qf 3612 20 organ organ NN cord-022526-j9kg00qf 3612 21 infection infection NN cord-022526-j9kg00qf 3612 22 . . . cord-022526-j9kg00qf 3613 1 50 50 CD cord-022526-j9kg00qf 3613 2 , , , cord-022526-j9kg00qf 3613 3 59 59 CD cord-022526-j9kg00qf 3614 1 However however RB cord-022526-j9kg00qf 3614 2 , , , cord-022526-j9kg00qf 3614 3 in in IN cord-022526-j9kg00qf 3614 4 naturally naturally RB cord-022526-j9kg00qf 3614 5 infected infect VBN cord-022526-j9kg00qf 3614 6 horses horse NNS cord-022526-j9kg00qf 3614 7 , , , cord-022526-j9kg00qf 3614 8 whether whether IN cord-022526-j9kg00qf 3614 9 leukocytes leukocyte NNS cord-022526-j9kg00qf 3614 10 of of IN cord-022526-j9kg00qf 3614 11 monocytic monocytic JJ cord-022526-j9kg00qf 3614 12 lineage lineage NN cord-022526-j9kg00qf 3614 13 or or CC cord-022526-j9kg00qf 3614 14 epithelial epithelial JJ cord-022526-j9kg00qf 3614 15 cells cell NNS cord-022526-j9kg00qf 3614 16 are be VBP cord-022526-j9kg00qf 3614 17 infected infect VBN cord-022526-j9kg00qf 3614 18 first first RB cord-022526-j9kg00qf 3614 19 is be VBZ cord-022526-j9kg00qf 3614 20 unclear unclear JJ cord-022526-j9kg00qf 3614 21 . . . cord-022526-j9kg00qf 3615 1 The the DT cord-022526-j9kg00qf 3615 2 target target NN cord-022526-j9kg00qf 3615 3 organ organ NN cord-022526-j9kg00qf 3615 4 is be VBZ cord-022526-j9kg00qf 3615 5 the the DT cord-022526-j9kg00qf 3615 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3615 7 mucosa mucosa NN cord-022526-j9kg00qf 3615 8 , , , cord-022526-j9kg00qf 3615 9 with with IN cord-022526-j9kg00qf 3615 10 the the DT cord-022526-j9kg00qf 3615 11 most most RBS cord-022526-j9kg00qf 3615 12 severe severe JJ cord-022526-j9kg00qf 3615 13 lesions lesion NNS cord-022526-j9kg00qf 3615 14 found find VBN cord-022526-j9kg00qf 3615 15 in in IN cord-022526-j9kg00qf 3615 16 the the DT cord-022526-j9kg00qf 3615 17 large large JJ cord-022526-j9kg00qf 3615 18 intestine intestine NN cord-022526-j9kg00qf 3615 19 . . . cord-022526-j9kg00qf 3616 1 59 59 CD cord-022526-j9kg00qf 3616 2 , , , cord-022526-j9kg00qf 3616 3 60 60 CD cord-022526-j9kg00qf 3616 4 Infection infection NN cord-022526-j9kg00qf 3616 5 of of IN cord-022526-j9kg00qf 3616 6 human human JJ cord-022526-j9kg00qf 3616 7 colonic colonic JJ cord-022526-j9kg00qf 3616 8 cells cell NNS cord-022526-j9kg00qf 3616 9 in in IN cord-022526-j9kg00qf 3616 10 vitro vitro FW cord-022526-j9kg00qf 3616 11 does do VBZ cord-022526-j9kg00qf 3616 12 not not RB cord-022526-j9kg00qf 3616 13 cause cause VB cord-022526-j9kg00qf 3616 14 major major JJ cord-022526-j9kg00qf 3616 15 cytopathologic cytopathologic JJ cord-022526-j9kg00qf 3616 16 effects effect NNS cord-022526-j9kg00qf 3616 17 for for IN cord-022526-j9kg00qf 3616 18 several several JJ cord-022526-j9kg00qf 3616 19 days day NNS cord-022526-j9kg00qf 3616 20 . . . cord-022526-j9kg00qf 3617 1 Disruption disruption NN cord-022526-j9kg00qf 3617 2 of of IN cord-022526-j9kg00qf 3617 3 the the DT cord-022526-j9kg00qf 3617 4 microvilli microvilli NN cord-022526-j9kg00qf 3617 5 in in IN cord-022526-j9kg00qf 3617 6 the the DT cord-022526-j9kg00qf 3617 7 region region NN cord-022526-j9kg00qf 3617 8 of of IN cord-022526-j9kg00qf 3617 9 the the DT cord-022526-j9kg00qf 3617 10 plasma plasma NN cord-022526-j9kg00qf 3617 11 membrane membrane NN cord-022526-j9kg00qf 3617 12 where where WRB cord-022526-j9kg00qf 3617 13 sodium sodium NN cord-022526-j9kg00qf 3617 14 chloride chloride NN cord-022526-j9kg00qf 3617 15 channels channel NNS cord-022526-j9kg00qf 3617 16 are be VBP cord-022526-j9kg00qf 3617 17 located locate VBN cord-022526-j9kg00qf 3617 18 has have VBZ cord-022526-j9kg00qf 3617 19 been be VBN cord-022526-j9kg00qf 3617 20 observed observe VBN cord-022526-j9kg00qf 3617 21 in in IN cord-022526-j9kg00qf 3617 22 human human JJ cord-022526-j9kg00qf 3617 23 colonic colonic JJ cord-022526-j9kg00qf 3617 24 cell cell NN cord-022526-j9kg00qf 3617 25 cultures culture NNS cord-022526-j9kg00qf 3617 26 . . . cord-022526-j9kg00qf 3618 1 61 61 CD cord-022526-j9kg00qf 3618 2 Infection infection NN cord-022526-j9kg00qf 3618 3 in in IN cord-022526-j9kg00qf 3618 4 horses horse NNS cord-022526-j9kg00qf 3618 5 is be VBZ cord-022526-j9kg00qf 3618 6 associated associate VBN cord-022526-j9kg00qf 3618 7 with with IN cord-022526-j9kg00qf 3618 8 variable variable JJ cord-022526-j9kg00qf 3618 9 degrees degree NNS cord-022526-j9kg00qf 3618 10 of of IN cord-022526-j9kg00qf 3618 11 morphologic morphologic JJ cord-022526-j9kg00qf 3618 12 damage damage NN cord-022526-j9kg00qf 3618 13 . . . cord-022526-j9kg00qf 3619 1 59 59 CD cord-022526-j9kg00qf 3619 2 , , , cord-022526-j9kg00qf 3619 3 60 60 CD cord-022526-j9kg00qf 3619 4 Mild mild JJ cord-022526-j9kg00qf 3619 5 morphologic morphologic JJ cord-022526-j9kg00qf 3619 6 damage damage NN cord-022526-j9kg00qf 3619 7 and and CC cord-022526-j9kg00qf 3619 8 mononuclear mononuclear JJ cord-022526-j9kg00qf 3619 9 cell cell NN cord-022526-j9kg00qf 3619 10 infiltration infiltration NN cord-022526-j9kg00qf 3619 11 of of IN cord-022526-j9kg00qf 3619 12 the the DT cord-022526-j9kg00qf 3619 13 lamina lamina JJ cord-022526-j9kg00qf 3619 14 propria propria NN cord-022526-j9kg00qf 3619 15 occur occur VBP cord-022526-j9kg00qf 3619 16 early early RB cord-022526-j9kg00qf 3619 17 during during IN cord-022526-j9kg00qf 3619 18 the the DT cord-022526-j9kg00qf 3619 19 infection infection NN cord-022526-j9kg00qf 3619 20 , , , cord-022526-j9kg00qf 3619 21 but but CC cord-022526-j9kg00qf 3619 22 fibrinous fibrinous NNP cord-022526-j9kg00qf 3619 23 , , , cord-022526-j9kg00qf 3619 24 necrotizing necrotize VBG cord-022526-j9kg00qf 3619 25 typhlocolitis typhlocolitis RB cord-022526-j9kg00qf 3619 26 with with IN cord-022526-j9kg00qf 3619 27 severe severe JJ cord-022526-j9kg00qf 3619 28 mucosal mucosal JJ cord-022526-j9kg00qf 3619 29 ulceration ulceration NN cord-022526-j9kg00qf 3619 30 and and CC cord-022526-j9kg00qf 3619 31 inflammation inflammation NN cord-022526-j9kg00qf 3619 32 of of IN cord-022526-j9kg00qf 3619 33 the the DT cord-022526-j9kg00qf 3619 34 lamina lamina JJ cord-022526-j9kg00qf 3619 35 propria propria FW cord-022526-j9kg00qf 3619 36 may may MD cord-022526-j9kg00qf 3619 37 occur occur VB cord-022526-j9kg00qf 3619 38 later later RB cord-022526-j9kg00qf 3619 39 in in IN cord-022526-j9kg00qf 3619 40 the the DT cord-022526-j9kg00qf 3619 41 disease disease NN cord-022526-j9kg00qf 3619 42 . . . cord-022526-j9kg00qf 3620 1 Vasculitis vasculitis NN cord-022526-j9kg00qf 3620 2 and and CC cord-022526-j9kg00qf 3620 3 intravascular intravascular JJ cord-022526-j9kg00qf 3620 4 coagulation coagulation NN cord-022526-j9kg00qf 3620 5 are be VBP cord-022526-j9kg00qf 3620 6 consistent consistent JJ cord-022526-j9kg00qf 3620 7 features feature NNS cord-022526-j9kg00qf 3620 8 in in IN cord-022526-j9kg00qf 3620 9 the the DT cord-022526-j9kg00qf 3620 10 large large JJ cord-022526-j9kg00qf 3620 11 intestine intestine NN cord-022526-j9kg00qf 3620 12 , , , cord-022526-j9kg00qf 3620 13 with with IN cord-022526-j9kg00qf 3620 14 perivascular perivascular JJ cord-022526-j9kg00qf 3620 15 edema edema NN cord-022526-j9kg00qf 3620 16 . . . cord-022526-j9kg00qf 3621 1 60 60 CD cord-022526-j9kg00qf 3622 1 One one PRP cord-022526-j9kg00qf 3622 2 can can MD cord-022526-j9kg00qf 3622 3 observe observe VB cord-022526-j9kg00qf 3622 4 N. N. NNP cord-022526-j9kg00qf 3622 5 risticii risticii NN cord-022526-j9kg00qf 3622 6 in in IN cord-022526-j9kg00qf 3622 7 mucosal mucosal JJ cord-022526-j9kg00qf 3622 8 cells cell NNS cord-022526-j9kg00qf 3622 9 and and CC cord-022526-j9kg00qf 3622 10 macrophages macrophage NNS cord-022526-j9kg00qf 3622 11 and and CC cord-022526-j9kg00qf 3622 12 mast mast NN cord-022526-j9kg00qf 3622 13 cells cell NNS cord-022526-j9kg00qf 3622 14 of of IN cord-022526-j9kg00qf 3622 15 the the DT cord-022526-j9kg00qf 3622 16 lamina lamina JJ cord-022526-j9kg00qf 3622 17 propria propria NN cord-022526-j9kg00qf 3622 18 . . . cord-022526-j9kg00qf 3623 1 59,60 59,60 CD cord-022526-j9kg00qf 3623 2 N. N. NNP cord-022526-j9kg00qf 3623 3 risticii risticii NN cord-022526-j9kg00qf 3623 4 can can MD cord-022526-j9kg00qf 3623 5 survive survive VB cord-022526-j9kg00qf 3623 6 and and CC cord-022526-j9kg00qf 3623 7 multiply multiply VB cord-022526-j9kg00qf 3623 8 in in IN cord-022526-j9kg00qf 3623 9 macrophages macrophage NNS cord-022526-j9kg00qf 3623 10 by by IN cord-022526-j9kg00qf 3623 11 inhibiting inhibit VBG cord-022526-j9kg00qf 3623 12 the the DT cord-022526-j9kg00qf 3623 13 production production NN cord-022526-j9kg00qf 3623 14 of of IN cord-022526-j9kg00qf 3623 15 reactive reactive JJ cord-022526-j9kg00qf 3623 16 oxygen oxygen NN cord-022526-j9kg00qf 3623 17 intermediates intermediate NNS cord-022526-j9kg00qf 3623 18 and and CC cord-022526-j9kg00qf 3623 19 by by IN cord-022526-j9kg00qf 3623 20 avoiding avoid VBG cord-022526-j9kg00qf 3623 21 lysosomal lysosomal JJ cord-022526-j9kg00qf 3623 22 digestion digestion NN cord-022526-j9kg00qf 3623 23 by by IN cord-022526-j9kg00qf 3623 24 blocking block VBG cord-022526-j9kg00qf 3623 25 phagosome phagosome NN cord-022526-j9kg00qf 3623 26 - - HYPH cord-022526-j9kg00qf 3623 27 lysosome lysosome NN cord-022526-j9kg00qf 3623 28 fusion fusion NN cord-022526-j9kg00qf 3623 29 . . . cord-022526-j9kg00qf 3624 1 [ [ -LRB- cord-022526-j9kg00qf 3624 2 62 62 CD cord-022526-j9kg00qf 3624 3 ] ] -RRB- cord-022526-j9kg00qf 3624 4 [ [ -LRB- cord-022526-j9kg00qf 3624 5 63 63 CD cord-022526-j9kg00qf 3624 6 ] ] -RRB- cord-022526-j9kg00qf 3624 7 [ [ -LRB- cord-022526-j9kg00qf 3624 8 64 64 CD cord-022526-j9kg00qf 3624 9 ] ] -RRB- cord-022526-j9kg00qf 3625 1 Evidence evidence NN cord-022526-j9kg00qf 3625 2 of of IN cord-022526-j9kg00qf 3625 3 impaired impaired JJ cord-022526-j9kg00qf 3625 4 sodium sodium NN cord-022526-j9kg00qf 3625 5 chloride chloride NN cord-022526-j9kg00qf 3625 6 absorption absorption NN cord-022526-j9kg00qf 3625 7 in in IN cord-022526-j9kg00qf 3625 8 the the DT cord-022526-j9kg00qf 3625 9 colon colon NN cord-022526-j9kg00qf 3625 10 has have VBZ cord-022526-j9kg00qf 3625 11 been be VBN cord-022526-j9kg00qf 3625 12 suggested suggest VBN cord-022526-j9kg00qf 3625 13 to to TO cord-022526-j9kg00qf 3625 14 contribute contribute VB cord-022526-j9kg00qf 3625 15 to to IN cord-022526-j9kg00qf 3625 16 diarrhea diarrhea NN cord-022526-j9kg00qf 3625 17 in in IN cord-022526-j9kg00qf 3625 18 infected infected JJ cord-022526-j9kg00qf 3625 19 horses horse NNS cord-022526-j9kg00qf 3625 20 and and CC cord-022526-j9kg00qf 3625 21 may may MD cord-022526-j9kg00qf 3625 22 be be VB cord-022526-j9kg00qf 3625 23 related relate VBN cord-022526-j9kg00qf 3625 24 to to IN cord-022526-j9kg00qf 3625 25 destruction destruction NN cord-022526-j9kg00qf 3625 26 of of IN cord-022526-j9kg00qf 3625 27 the the DT cord-022526-j9kg00qf 3625 28 enterocyte enterocyte NNP cord-022526-j9kg00qf 3625 29 membrane membrane NNP cord-022526-j9kg00qf 3625 30 structure structure NN cord-022526-j9kg00qf 3625 31 in in IN cord-022526-j9kg00qf 3625 32 the the DT cord-022526-j9kg00qf 3625 33 region region NN cord-022526-j9kg00qf 3625 34 of of IN cord-022526-j9kg00qf 3625 35 sodium sodium NN cord-022526-j9kg00qf 3625 36 chloride chloride NN cord-022526-j9kg00qf 3625 37 channels channel NNS cord-022526-j9kg00qf 3625 38 . . . cord-022526-j9kg00qf 3626 1 61 61 CD cord-022526-j9kg00qf 3626 2 , , , cord-022526-j9kg00qf 3626 3 65 65 CD cord-022526-j9kg00qf 3626 4 Direct direct JJ cord-022526-j9kg00qf 3626 5 injury injury NN cord-022526-j9kg00qf 3626 6 to to IN cord-022526-j9kg00qf 3626 7 the the DT cord-022526-j9kg00qf 3626 8 mucosa mucosa NN cord-022526-j9kg00qf 3626 9 by by IN cord-022526-j9kg00qf 3626 10 N. N. NNP cord-022526-j9kg00qf 3626 11 risticii risticii NN cord-022526-j9kg00qf 3626 12 and and CC cord-022526-j9kg00qf 3626 13 colonic colonic JJ cord-022526-j9kg00qf 3626 14 inflammation inflammation NN cord-022526-j9kg00qf 3626 15 are be VBP cord-022526-j9kg00qf 3626 16 likely likely JJ cord-022526-j9kg00qf 3626 17 to to TO cord-022526-j9kg00qf 3626 18 be be VB cord-022526-j9kg00qf 3626 19 prominent prominent JJ cord-022526-j9kg00qf 3626 20 features feature NNS cord-022526-j9kg00qf 3626 21 leading lead VBG cord-022526-j9kg00qf 3626 22 to to IN cord-022526-j9kg00qf 3626 23 diarrhea diarrhea NN cord-022526-j9kg00qf 3626 24 , , , cord-022526-j9kg00qf 3626 25 especially especially RB cord-022526-j9kg00qf 3626 26 later later RB cord-022526-j9kg00qf 3626 27 in in IN cord-022526-j9kg00qf 3626 28 the the DT cord-022526-j9kg00qf 3626 29 disease disease NN cord-022526-j9kg00qf 3626 30 . . . cord-022526-j9kg00qf 3627 1 60 60 CD cord-022526-j9kg00qf 3627 2 Fluid Fluid NNP cord-022526-j9kg00qf 3627 3 , , , cord-022526-j9kg00qf 3627 4 protein protein NN cord-022526-j9kg00qf 3627 5 , , , cord-022526-j9kg00qf 3627 6 and and CC cord-022526-j9kg00qf 3627 7 electrolyte electrolyte JJ cord-022526-j9kg00qf 3627 8 loss loss NN cord-022526-j9kg00qf 3627 9 likely likely RB cord-022526-j9kg00qf 3627 10 is be VBZ cord-022526-j9kg00qf 3627 11 caused cause VBN cord-022526-j9kg00qf 3627 12 by by IN cord-022526-j9kg00qf 3627 13 mucosal mucosal JJ cord-022526-j9kg00qf 3627 14 injury injury NN cord-022526-j9kg00qf 3627 15 and and CC cord-022526-j9kg00qf 3627 16 effects effect NNS cord-022526-j9kg00qf 3627 17 on on IN cord-022526-j9kg00qf 3627 18 enterocyte enterocyte JJ cord-022526-j9kg00qf 3627 19 fluid fluid JJ cord-022526-j9kg00qf 3627 20 secretion secretion NN cord-022526-j9kg00qf 3627 21 caused cause VBN cord-022526-j9kg00qf 3627 22 by by IN cord-022526-j9kg00qf 3627 23 the the DT cord-022526-j9kg00qf 3627 24 inflammatory inflammatory JJ cord-022526-j9kg00qf 3627 25 response response NN cord-022526-j9kg00qf 3627 26 . . . cord-022526-j9kg00qf 3628 1 Like like IN cord-022526-j9kg00qf 3628 2 other other JJ cord-022526-j9kg00qf 3628 3 inflammatory inflammatory JJ cord-022526-j9kg00qf 3628 4 conditions condition NNS cord-022526-j9kg00qf 3628 5 of of IN cord-022526-j9kg00qf 3628 6 the the DT cord-022526-j9kg00qf 3628 7 colon colon NN cord-022526-j9kg00qf 3628 8 , , , cord-022526-j9kg00qf 3628 9 systemic systemic JJ cord-022526-j9kg00qf 3628 10 inflammation inflammation NN cord-022526-j9kg00qf 3628 11 caused cause VBN cord-022526-j9kg00qf 3628 12 by by IN cord-022526-j9kg00qf 3628 13 absorption absorption NN cord-022526-j9kg00qf 3628 14 of of IN cord-022526-j9kg00qf 3628 15 bacteria bacteria NNS cord-022526-j9kg00qf 3628 16 and and CC cord-022526-j9kg00qf 3628 17 bacterial bacterial JJ cord-022526-j9kg00qf 3628 18 products product NNS cord-022526-j9kg00qf 3628 19 is be VBZ cord-022526-j9kg00qf 3628 20 a a DT cord-022526-j9kg00qf 3628 21 potential potential JJ cord-022526-j9kg00qf 3628 22 complication complication NN cord-022526-j9kg00qf 3628 23 of of IN cord-022526-j9kg00qf 3628 24 N. N. NNP cord-022526-j9kg00qf 3628 25 risticii risticii JJ cord-022526-j9kg00qf 3628 26 infections infection NNS cord-022526-j9kg00qf 3628 27 if if IN cord-022526-j9kg00qf 3628 28 mucosal mucosal JJ cord-022526-j9kg00qf 3628 29 injury injury NN cord-022526-j9kg00qf 3628 30 is be VBZ cord-022526-j9kg00qf 3628 31 severe severe JJ cord-022526-j9kg00qf 3628 32 , , , cord-022526-j9kg00qf 3628 33 which which WDT cord-022526-j9kg00qf 3628 34 contributes contribute VBZ cord-022526-j9kg00qf 3628 35 to to IN cord-022526-j9kg00qf 3628 36 the the DT cord-022526-j9kg00qf 3628 37 clinical clinical JJ cord-022526-j9kg00qf 3628 38 signs sign NNS cord-022526-j9kg00qf 3628 39 seen see VBN cord-022526-j9kg00qf 3628 40 during during IN cord-022526-j9kg00qf 3628 41 the the DT cord-022526-j9kg00qf 3628 42 disease disease NN cord-022526-j9kg00qf 3628 43 . . . cord-022526-j9kg00qf 3629 1 N. N. NNP cord-022526-j9kg00qf 3629 2 risticii risticii NNP cord-022526-j9kg00qf 3629 3 infection infection NN cord-022526-j9kg00qf 3629 4 is be VBZ cord-022526-j9kg00qf 3629 5 clinically clinically RB cord-022526-j9kg00qf 3629 6 similar similar JJ cord-022526-j9kg00qf 3629 7 to to IN cord-022526-j9kg00qf 3629 8 other other JJ cord-022526-j9kg00qf 3629 9 forms form NNS cord-022526-j9kg00qf 3629 10 of of IN cord-022526-j9kg00qf 3629 11 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3629 12 and and CC cord-022526-j9kg00qf 3629 13 is be VBZ cord-022526-j9kg00qf 3629 14 characterized characterize VBN cord-022526-j9kg00qf 3629 15 by by IN cord-022526-j9kg00qf 3629 16 anorexia anorexia NN cord-022526-j9kg00qf 3629 17 , , , cord-022526-j9kg00qf 3629 18 depression depression NN cord-022526-j9kg00qf 3629 19 , , , cord-022526-j9kg00qf 3629 20 and and CC cord-022526-j9kg00qf 3629 21 fever fever NN cord-022526-j9kg00qf 3629 22 . . . cord-022526-j9kg00qf 3630 1 48 48 CD cord-022526-j9kg00qf 3630 2 , , , cord-022526-j9kg00qf 3630 3 60 60 CD cord-022526-j9kg00qf 3630 4 , , , cord-022526-j9kg00qf 3630 5 66 66 CD cord-022526-j9kg00qf 3630 6 Experimental experimental JJ cord-022526-j9kg00qf 3630 7 infections infection NNS cord-022526-j9kg00qf 3630 8 produce produce VBP cord-022526-j9kg00qf 3630 9 a a DT cord-022526-j9kg00qf 3630 10 biphasic biphasic JJ cord-022526-j9kg00qf 3630 11 fever fever NN cord-022526-j9kg00qf 3630 12 occurring occur VBG cord-022526-j9kg00qf 3630 13 6 6 CD cord-022526-j9kg00qf 3630 14 to to TO cord-022526-j9kg00qf 3630 15 7 7 CD cord-022526-j9kg00qf 3630 16 days day NNS cord-022526-j9kg00qf 3630 17 apart apart RB cord-022526-j9kg00qf 3630 18 . . . cord-022526-j9kg00qf 3631 1 Decreased decrease VBN cord-022526-j9kg00qf 3631 2 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3631 3 motility motility NN cord-022526-j9kg00qf 3631 4 , , , cord-022526-j9kg00qf 3631 5 manifested manifest VBN cord-022526-j9kg00qf 3631 6 as as IN cord-022526-j9kg00qf 3631 7 reduced reduce VBN cord-022526-j9kg00qf 3631 8 borborygmi borborygmi NN cord-022526-j9kg00qf 3631 9 , , , cord-022526-j9kg00qf 3631 10 occurs occur VBZ cord-022526-j9kg00qf 3631 11 during during IN cord-022526-j9kg00qf 3631 12 the the DT cord-022526-j9kg00qf 3631 13 early early JJ cord-022526-j9kg00qf 3631 14 stages stage NNS cord-022526-j9kg00qf 3631 15 before before IN cord-022526-j9kg00qf 3631 16 the the DT cord-022526-j9kg00qf 3631 17 onset onset NN cord-022526-j9kg00qf 3631 18 of of IN cord-022526-j9kg00qf 3631 19 diarrhea diarrhea NN cord-022526-j9kg00qf 3631 20 . . . cord-022526-j9kg00qf 3632 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3632 2 occurs occur VBZ cord-022526-j9kg00qf 3632 3 in in IN cord-022526-j9kg00qf 3632 4 75 75 CD cord-022526-j9kg00qf 3632 5 % % NN cord-022526-j9kg00qf 3632 6 of of IN cord-022526-j9kg00qf 3632 7 cases case NNS cord-022526-j9kg00qf 3632 8 and and CC cord-022526-j9kg00qf 3632 9 occurs occur VBZ cord-022526-j9kg00qf 3632 10 2 2 CD cord-022526-j9kg00qf 3632 11 days day NNS cord-022526-j9kg00qf 3632 12 after after IN cord-022526-j9kg00qf 3632 13 the the DT cord-022526-j9kg00qf 3632 14 second second JJ cord-022526-j9kg00qf 3632 15 fever fever NN cord-022526-j9kg00qf 3632 16 episode episode NN cord-022526-j9kg00qf 3632 17 during during IN cord-022526-j9kg00qf 3632 18 experimental experimental JJ cord-022526-j9kg00qf 3632 19 infections infection NNS cord-022526-j9kg00qf 3632 20 . . . cord-022526-j9kg00qf 3633 1 66 66 CD cord-022526-j9kg00qf 3633 2 , , , cord-022526-j9kg00qf 3633 3 67 67 CD cord-022526-j9kg00qf 3634 1 The the DT cord-022526-j9kg00qf 3634 2 diarrhea diarrhea NN cord-022526-j9kg00qf 3634 3 can can MD cord-022526-j9kg00qf 3634 4 be be VB cord-022526-j9kg00qf 3634 5 moderate moderate JJ cord-022526-j9kg00qf 3634 6 to to TO cord-022526-j9kg00qf 3634 7 severe severe JJ cord-022526-j9kg00qf 3634 8 and and CC cord-022526-j9kg00qf 3634 9 dehydrating dehydrate VBG cord-022526-j9kg00qf 3634 10 . . . cord-022526-j9kg00qf 3635 1 Ileus Ileus NNP cord-022526-j9kg00qf 3635 2 can can MD cord-022526-j9kg00qf 3635 3 develop develop VB cord-022526-j9kg00qf 3635 4 at at IN cord-022526-j9kg00qf 3635 5 any any DT cord-022526-j9kg00qf 3635 6 stage stage NN cord-022526-j9kg00qf 3635 7 of of IN cord-022526-j9kg00qf 3635 8 the the DT cord-022526-j9kg00qf 3635 9 disease disease NN cord-022526-j9kg00qf 3635 10 and and CC cord-022526-j9kg00qf 3635 11 can can MD cord-022526-j9kg00qf 3635 12 cause cause VB cord-022526-j9kg00qf 3635 13 signs sign NNS cord-022526-j9kg00qf 3635 14 of of IN cord-022526-j9kg00qf 3635 15 moderate moderate JJ cord-022526-j9kg00qf 3635 16 to to IN cord-022526-j9kg00qf 3635 17 severe severe JJ cord-022526-j9kg00qf 3635 18 colic colic NN cord-022526-j9kg00qf 3635 19 . . . cord-022526-j9kg00qf 3636 1 Systemic systemic JJ cord-022526-j9kg00qf 3636 2 signs sign NNS cord-022526-j9kg00qf 3636 3 of of IN cord-022526-j9kg00qf 3636 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3636 5 , , , cord-022526-j9kg00qf 3636 6 shock shock NN cord-022526-j9kg00qf 3636 7 , , , cord-022526-j9kg00qf 3636 8 and and CC cord-022526-j9kg00qf 3636 9 peripheral peripheral JJ cord-022526-j9kg00qf 3636 10 edema edema NN cord-022526-j9kg00qf 3636 11 may may MD cord-022526-j9kg00qf 3636 12 occur occur VB cord-022526-j9kg00qf 3636 13 and and CC cord-022526-j9kg00qf 3636 14 are be VBP cord-022526-j9kg00qf 3636 15 similar similar JJ cord-022526-j9kg00qf 3636 16 to to IN cord-022526-j9kg00qf 3636 17 those those DT cord-022526-j9kg00qf 3636 18 described describe VBN cord-022526-j9kg00qf 3636 19 for for IN cord-022526-j9kg00qf 3636 20 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3636 21 . . . cord-022526-j9kg00qf 3637 1 Experimental experimental JJ cord-022526-j9kg00qf 3637 2 and and CC cord-022526-j9kg00qf 3637 3 natural natural JJ cord-022526-j9kg00qf 3637 4 infection infection NN cord-022526-j9kg00qf 3637 5 with with IN cord-022526-j9kg00qf 3637 6 N. N. NNP cord-022526-j9kg00qf 3637 7 risticii risticii NN cord-022526-j9kg00qf 3637 8 can can MD cord-022526-j9kg00qf 3637 9 cause cause VB cord-022526-j9kg00qf 3637 10 abortion abortion NN cord-022526-j9kg00qf 3637 11 of of IN cord-022526-j9kg00qf 3637 12 infected infected JJ cord-022526-j9kg00qf 3637 13 fetuses fetus NNS cord-022526-j9kg00qf 3637 14 in in IN cord-022526-j9kg00qf 3637 15 pregnant pregnant JJ cord-022526-j9kg00qf 3637 16 mares mare NNS cord-022526-j9kg00qf 3637 17 . . . cord-022526-j9kg00qf 3638 1 68 68 CD cord-022526-j9kg00qf 3639 1 , , , cord-022526-j9kg00qf 3639 2 69 69 CD cord-022526-j9kg00qf 3639 3 Laminitis Laminitis NNP cord-022526-j9kg00qf 3639 4 is be VBZ cord-022526-j9kg00qf 3639 5 a a DT cord-022526-j9kg00qf 3639 6 complication complication NN cord-022526-j9kg00qf 3639 7 in in IN cord-022526-j9kg00qf 3639 8 20 20 CD cord-022526-j9kg00qf 3639 9 % % NN cord-022526-j9kg00qf 3639 10 to to TO cord-022526-j9kg00qf 3639 11 30 30 CD cord-022526-j9kg00qf 3639 12 % % NN cord-022526-j9kg00qf 3639 13 of of IN cord-022526-j9kg00qf 3639 14 naturally naturally RB cord-022526-j9kg00qf 3639 15 occurring occur VBG cord-022526-j9kg00qf 3639 16 cases case NNS cord-022526-j9kg00qf 3639 17 and and CC cord-022526-j9kg00qf 3639 18 is be VBZ cord-022526-j9kg00qf 3639 19 often often RB cord-022526-j9kg00qf 3639 20 severe severe JJ cord-022526-j9kg00qf 3639 21 . . . cord-022526-j9kg00qf 3640 1 Other other JJ cord-022526-j9kg00qf 3640 2 complications complication NNS cord-022526-j9kg00qf 3640 3 include include VBP cord-022526-j9kg00qf 3640 4 protein protein NN cord-022526-j9kg00qf 3640 5 - - HYPH cord-022526-j9kg00qf 3640 6 losing lose VBG cord-022526-j9kg00qf 3640 7 enteropathy enteropathy NN cord-022526-j9kg00qf 3640 8 , , , cord-022526-j9kg00qf 3640 9 thrombosis thrombosis NN cord-022526-j9kg00qf 3640 10 , , , cord-022526-j9kg00qf 3640 11 and and CC cord-022526-j9kg00qf 3640 12 renal renal JJ cord-022526-j9kg00qf 3640 13 failure failure NN cord-022526-j9kg00qf 3640 14 , , , cord-022526-j9kg00qf 3640 15 as as IN cord-022526-j9kg00qf 3640 16 described describe VBN cord-022526-j9kg00qf 3640 17 for for IN cord-022526-j9kg00qf 3640 18 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3640 19 . . . cord-022526-j9kg00qf 3641 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 3641 2 abnormalities abnormality NNS cord-022526-j9kg00qf 3641 3 reflect reflect VBP cord-022526-j9kg00qf 3641 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3641 5 , , , cord-022526-j9kg00qf 3641 6 dehydration dehydration NN cord-022526-j9kg00qf 3641 7 , , , cord-022526-j9kg00qf 3641 8 and and CC cord-022526-j9kg00qf 3641 9 sepsis sepsis NN cord-022526-j9kg00qf 3641 10 and and CC cord-022526-j9kg00qf 3641 11 are be VBP cord-022526-j9kg00qf 3641 12 essentially essentially RB cord-022526-j9kg00qf 3641 13 identical identical JJ cord-022526-j9kg00qf 3641 14 to to IN cord-022526-j9kg00qf 3641 15 those those DT cord-022526-j9kg00qf 3641 16 described describe VBN cord-022526-j9kg00qf 3641 17 for for IN cord-022526-j9kg00qf 3641 18 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3641 19 . . . cord-022526-j9kg00qf 3642 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 3642 2 with with IN cord-022526-j9kg00qf 3642 3 a a DT cord-022526-j9kg00qf 3642 4 left left JJ cord-022526-j9kg00qf 3642 5 shift shift NN cord-022526-j9kg00qf 3642 6 is be VBZ cord-022526-j9kg00qf 3642 7 a a DT cord-022526-j9kg00qf 3642 8 consistent consistent JJ cord-022526-j9kg00qf 3642 9 feature feature NN cord-022526-j9kg00qf 3642 10 and and CC cord-022526-j9kg00qf 3642 11 occurs occur VBZ cord-022526-j9kg00qf 3642 12 concurrently concurrently RB cord-022526-j9kg00qf 3642 13 with with IN cord-022526-j9kg00qf 3642 14 or or CC cord-022526-j9kg00qf 3642 15 soon soon RB cord-022526-j9kg00qf 3642 16 after after IN cord-022526-j9kg00qf 3642 17 the the DT cord-022526-j9kg00qf 3642 18 onset onset NN cord-022526-j9kg00qf 3642 19 of of IN cord-022526-j9kg00qf 3642 20 diarrhea diarrhea NN cord-022526-j9kg00qf 3642 21 . . . cord-022526-j9kg00qf 3643 1 Thrombocytopenia Thrombocytopenia NNP cord-022526-j9kg00qf 3643 2 is be VBZ cord-022526-j9kg00qf 3643 3 common common JJ cord-022526-j9kg00qf 3643 4 and and CC cord-022526-j9kg00qf 3643 5 often often RB cord-022526-j9kg00qf 3643 6 severe severe JJ cord-022526-j9kg00qf 3643 7 . . . cord-022526-j9kg00qf 3644 1 67 67 CD cord-022526-j9kg00qf 3644 2 Neutrophilic Neutrophilic NNP cord-022526-j9kg00qf 3644 3 leukocytosis leukocytosis NN cord-022526-j9kg00qf 3644 4 occurs occur VBZ cord-022526-j9kg00qf 3644 5 later later RB cord-022526-j9kg00qf 3644 6 in in IN cord-022526-j9kg00qf 3644 7 the the DT cord-022526-j9kg00qf 3644 8 course course NN cord-022526-j9kg00qf 3644 9 of of IN cord-022526-j9kg00qf 3644 10 the the DT cord-022526-j9kg00qf 3644 11 disease disease NN cord-022526-j9kg00qf 3644 12 . . . cord-022526-j9kg00qf 3645 1 Hyperfibrinogenemia Hyperfibrinogenemia NNP cord-022526-j9kg00qf 3645 2 is be VBZ cord-022526-j9kg00qf 3645 3 usually usually RB cord-022526-j9kg00qf 3645 4 more more RBR cord-022526-j9kg00qf 3645 5 pronounced pronounced JJ cord-022526-j9kg00qf 3645 6 than than IN cord-022526-j9kg00qf 3645 7 that that DT cord-022526-j9kg00qf 3645 8 with with IN cord-022526-j9kg00qf 3645 9 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3645 10 . . . cord-022526-j9kg00qf 3646 1 Serum serum NN cord-022526-j9kg00qf 3646 2 electrolyte electrolyte NN cord-022526-j9kg00qf 3646 3 , , , cord-022526-j9kg00qf 3646 4 acid acid NN cord-022526-j9kg00qf 3646 5 - - HYPH cord-022526-j9kg00qf 3646 6 base base NN cord-022526-j9kg00qf 3646 7 , , , cord-022526-j9kg00qf 3646 8 and and CC cord-022526-j9kg00qf 3646 9 biochemical biochemical JJ cord-022526-j9kg00qf 3646 10 abnormalities abnormality NNS cord-022526-j9kg00qf 3646 11 are be VBP cord-022526-j9kg00qf 3646 12 also also RB cord-022526-j9kg00qf 3646 13 similar similar JJ cord-022526-j9kg00qf 3646 14 to to IN cord-022526-j9kg00qf 3646 15 those those DT cord-022526-j9kg00qf 3646 16 described describe VBN cord-022526-j9kg00qf 3646 17 for for IN cord-022526-j9kg00qf 3646 18 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3646 19 . . . cord-022526-j9kg00qf 3647 1 Coagulopathies coagulopathie NNS cord-022526-j9kg00qf 3647 2 are be VBP cord-022526-j9kg00qf 3647 3 common common JJ cord-022526-j9kg00qf 3647 4 during during IN cord-022526-j9kg00qf 3647 5 N. N. NNP cord-022526-j9kg00qf 3647 6 risticii risticii JJ cord-022526-j9kg00qf 3647 7 infection infection NN cord-022526-j9kg00qf 3647 8 and and CC cord-022526-j9kg00qf 3647 9 reflect reflect VB cord-022526-j9kg00qf 3647 10 activation activation NN cord-022526-j9kg00qf 3647 11 of of IN cord-022526-j9kg00qf 3647 12 coagulation coagulation NN cord-022526-j9kg00qf 3647 13 pathways pathway NNS cord-022526-j9kg00qf 3647 14 . . . cord-022526-j9kg00qf 3648 1 Disseminated disseminate VBN cord-022526-j9kg00qf 3648 2 intravascular intravascular JJ cord-022526-j9kg00qf 3648 3 coagulation coagulation NN cord-022526-j9kg00qf 3648 4 is be VBZ cord-022526-j9kg00qf 3648 5 common common JJ cord-022526-j9kg00qf 3648 6 and and CC cord-022526-j9kg00qf 3648 7 may may MD cord-022526-j9kg00qf 3648 8 be be VB cord-022526-j9kg00qf 3648 9 related relate VBN cord-022526-j9kg00qf 3648 10 to to IN cord-022526-j9kg00qf 3648 11 the the DT cord-022526-j9kg00qf 3648 12 high high JJ cord-022526-j9kg00qf 3648 13 frequency frequency NN cord-022526-j9kg00qf 3648 14 of of IN cord-022526-j9kg00qf 3648 15 laminitis laminitis NN cord-022526-j9kg00qf 3648 16 associated associate VBN cord-022526-j9kg00qf 3648 17 with with IN cord-022526-j9kg00qf 3648 18 N. n. NN cord-022526-j9kg00qf 3648 19 risticii risticii JJ cord-022526-j9kg00qf 3648 20 infection infection NN cord-022526-j9kg00qf 3648 21 . . . cord-022526-j9kg00qf 3649 1 70 70 CD cord-022526-j9kg00qf 3649 2 One one PRP cord-022526-j9kg00qf 3649 3 can can MD cord-022526-j9kg00qf 3649 4 not not RB cord-022526-j9kg00qf 3649 5 base base VB cord-022526-j9kg00qf 3649 6 diagnosis diagnosis NN cord-022526-j9kg00qf 3649 7 of of IN cord-022526-j9kg00qf 3649 8 N. N. NNP cord-022526-j9kg00qf 3649 9 risticii risticii NN cord-022526-j9kg00qf 3649 10 infection infection NN cord-022526-j9kg00qf 3649 11 solely solely RB cord-022526-j9kg00qf 3649 12 on on IN cord-022526-j9kg00qf 3649 13 clinical clinical JJ cord-022526-j9kg00qf 3649 14 signs sign NNS cord-022526-j9kg00qf 3649 15 because because IN cord-022526-j9kg00qf 3649 16 the the DT cord-022526-j9kg00qf 3649 17 disease disease NN cord-022526-j9kg00qf 3649 18 is be VBZ cord-022526-j9kg00qf 3649 19 clinically clinically RB cord-022526-j9kg00qf 3649 20 similar similar JJ cord-022526-j9kg00qf 3649 21 to to IN cord-022526-j9kg00qf 3649 22 other other JJ cord-022526-j9kg00qf 3649 23 forms form NNS cord-022526-j9kg00qf 3649 24 of of IN cord-022526-j9kg00qf 3649 25 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3649 26 . . . cord-022526-j9kg00qf 3650 1 However however RB cord-022526-j9kg00qf 3650 2 , , , cord-022526-j9kg00qf 3650 3 in in IN cord-022526-j9kg00qf 3650 4 endemic endemic JJ cord-022526-j9kg00qf 3650 5 areas area NNS cord-022526-j9kg00qf 3650 6 , , , cord-022526-j9kg00qf 3650 7 acute acute JJ cord-022526-j9kg00qf 3650 8 colitis colitis NN cord-022526-j9kg00qf 3650 9 is be VBZ cord-022526-j9kg00qf 3650 10 likely likely JJ cord-022526-j9kg00qf 3650 11 to to TO cord-022526-j9kg00qf 3650 12 be be VB cord-022526-j9kg00qf 3650 13 caused cause VBN cord-022526-j9kg00qf 3650 14 by by IN cord-022526-j9kg00qf 3650 15 N. N. NNP cord-022526-j9kg00qf 3650 16 risiticii risiticii NN cord-022526-j9kg00qf 3650 17 , , , cord-022526-j9kg00qf 3650 18 and and CC cord-022526-j9kg00qf 3650 19 thus thus RB cord-022526-j9kg00qf 3650 20 the the DT cord-022526-j9kg00qf 3650 21 clinical clinical JJ cord-022526-j9kg00qf 3650 22 signs sign NNS cord-022526-j9kg00qf 3650 23 of of IN cord-022526-j9kg00qf 3650 24 acute acute JJ cord-022526-j9kg00qf 3650 25 inflammatory inflammatory JJ cord-022526-j9kg00qf 3650 26 colitis colitis NN cord-022526-j9kg00qf 3650 27 in in IN cord-022526-j9kg00qf 3650 28 fact fact NN cord-022526-j9kg00qf 3650 29 may may MD cord-022526-j9kg00qf 3650 30 have have VB cord-022526-j9kg00qf 3650 31 a a DT cord-022526-j9kg00qf 3650 32 high high JJ cord-022526-j9kg00qf 3650 33 predictive predictive JJ cord-022526-j9kg00qf 3650 34 value value NN cord-022526-j9kg00qf 3650 35 . . . cord-022526-j9kg00qf 3651 1 Serologic Serologic NNP cord-022526-j9kg00qf 3651 2 evidence evidence NN cord-022526-j9kg00qf 3651 3 of of IN cord-022526-j9kg00qf 3651 4 infection infection NN cord-022526-j9kg00qf 3651 5 , , , cord-022526-j9kg00qf 3651 6 such such JJ cord-022526-j9kg00qf 3651 7 as as IN cord-022526-j9kg00qf 3651 8 rising rise VBG cord-022526-j9kg00qf 3651 9 antibody antibody NN cord-022526-j9kg00qf 3651 10 titers titer NNS cord-022526-j9kg00qf 3651 11 to to IN cord-022526-j9kg00qf 3651 12 N. N. NNP cord-022526-j9kg00qf 3651 13 risticii risticii NN cord-022526-j9kg00qf 3651 14 detected detect VBN cord-022526-j9kg00qf 3651 15 by by IN cord-022526-j9kg00qf 3651 16 indirect indirect JJ cord-022526-j9kg00qf 3651 17 immunofluorescence immunofluorescence NN cord-022526-j9kg00qf 3651 18 or or CC cord-022526-j9kg00qf 3651 19 enzymelinked enzymelinked JJ cord-022526-j9kg00qf 3651 20 immunosorbent immunosorbent JJ cord-022526-j9kg00qf 3651 21 assay assay NN cord-022526-j9kg00qf 3651 22 in in IN cord-022526-j9kg00qf 3651 23 paired paired JJ cord-022526-j9kg00qf 3651 24 serum serum NN cord-022526-j9kg00qf 3651 25 samples sample NNS cord-022526-j9kg00qf 3651 26 may may MD cord-022526-j9kg00qf 3651 27 be be VB cord-022526-j9kg00qf 3651 28 helpful helpful JJ cord-022526-j9kg00qf 3651 29 in in IN cord-022526-j9kg00qf 3651 30 establishing establish VBG cord-022526-j9kg00qf 3651 31 a a DT cord-022526-j9kg00qf 3651 32 diagnosis diagnosis NN cord-022526-j9kg00qf 3651 33 . . . cord-022526-j9kg00qf 3652 1 49 49 CD cord-022526-j9kg00qf 3652 2 , , , cord-022526-j9kg00qf 3652 3 71 71 CD cord-022526-j9kg00qf 3652 4 One one CD cord-022526-j9kg00qf 3652 5 should should MD cord-022526-j9kg00qf 3652 6 take take VB cord-022526-j9kg00qf 3652 7 care care NN cord-022526-j9kg00qf 3652 8 when when WRB cord-022526-j9kg00qf 3652 9 interpreting interpret VBG cord-022526-j9kg00qf 3652 10 the the DT cord-022526-j9kg00qf 3652 11 indirect indirect JJ cord-022526-j9kg00qf 3652 12 immunofluorescence immunofluorescence NN cord-022526-j9kg00qf 3652 13 serologic serologic NN cord-022526-j9kg00qf 3652 14 test test NN cord-022526-j9kg00qf 3652 15 for for IN cord-022526-j9kg00qf 3652 16 N. N. NNP cord-022526-j9kg00qf 3652 17 risticii risticii NNP cord-022526-j9kg00qf 3652 18 because because IN cord-022526-j9kg00qf 3652 19 the the DT cord-022526-j9kg00qf 3652 20 test test NN cord-022526-j9kg00qf 3652 21 appears appear VBZ cord-022526-j9kg00qf 3652 22 to to TO cord-022526-j9kg00qf 3652 23 have have VB cord-022526-j9kg00qf 3652 24 a a DT cord-022526-j9kg00qf 3652 25 high high JJ cord-022526-j9kg00qf 3652 26 false false JJ cord-022526-j9kg00qf 3652 27 - - HYPH cord-022526-j9kg00qf 3652 28 positive positive JJ cord-022526-j9kg00qf 3652 29 rate rate NN cord-022526-j9kg00qf 3652 30 . . . cord-022526-j9kg00qf 3653 1 72 72 CD cord-022526-j9kg00qf 3653 2 Culture culture NN cord-022526-j9kg00qf 3653 3 of of IN cord-022526-j9kg00qf 3653 4 the the DT cord-022526-j9kg00qf 3653 5 organism organism NN cord-022526-j9kg00qf 3653 6 from from IN cord-022526-j9kg00qf 3653 7 blood blood NN cord-022526-j9kg00qf 3653 8 is be VBZ cord-022526-j9kg00qf 3653 9 possible possible JJ cord-022526-j9kg00qf 3653 10 but but CC cord-022526-j9kg00qf 3653 11 is be VBZ cord-022526-j9kg00qf 3653 12 difficult difficult JJ cord-022526-j9kg00qf 3653 13 and and CC cord-022526-j9kg00qf 3653 14 is be VBZ cord-022526-j9kg00qf 3653 15 generally generally RB cord-022526-j9kg00qf 3653 16 useful useful JJ cord-022526-j9kg00qf 3653 17 only only RB cord-022526-j9kg00qf 3653 18 in in IN cord-022526-j9kg00qf 3653 19 the the DT cord-022526-j9kg00qf 3653 20 research research NN cord-022526-j9kg00qf 3653 21 laboratory laboratory NN cord-022526-j9kg00qf 3653 22 . . . cord-022526-j9kg00qf 3654 1 Recently recently RB cord-022526-j9kg00qf 3654 2 developed develop VBN cord-022526-j9kg00qf 3654 3 polymerase polymerase NN cord-022526-j9kg00qf 3654 4 chain chain NN cord-022526-j9kg00qf 3654 5 PCR PCR NNP cord-022526-j9kg00qf 3654 6 tests test NNS cord-022526-j9kg00qf 3654 7 for for IN cord-022526-j9kg00qf 3654 8 N. N. NNP cord-022526-j9kg00qf 3654 9 risticii risticii NNP cord-022526-j9kg00qf 3654 10 DNA DNA NNP cord-022526-j9kg00qf 3654 11 are be VBP cord-022526-j9kg00qf 3654 12 rapid rapid JJ cord-022526-j9kg00qf 3654 13 , , , cord-022526-j9kg00qf 3654 14 highly highly RB cord-022526-j9kg00qf 3654 15 sensitive sensitive JJ cord-022526-j9kg00qf 3654 16 ( ( -LRB- cord-022526-j9kg00qf 3654 17 as as RB cord-022526-j9kg00qf 3654 18 sensitive sensitive JJ cord-022526-j9kg00qf 3654 19 as as IN cord-022526-j9kg00qf 3654 20 culture culture NN cord-022526-j9kg00qf 3654 21 ) ) -RRB- cord-022526-j9kg00qf 3654 22 , , , cord-022526-j9kg00qf 3654 23 and and CC cord-022526-j9kg00qf 3654 24 specific specific JJ cord-022526-j9kg00qf 3654 25 for for IN cord-022526-j9kg00qf 3654 26 N. n. NN cord-022526-j9kg00qf 3654 27 risticii risticii JJ cord-022526-j9kg00qf 3654 28 infection infection NN cord-022526-j9kg00qf 3654 29 and and CC cord-022526-j9kg00qf 3654 30 can can MD cord-022526-j9kg00qf 3654 31 be be VB cord-022526-j9kg00qf 3654 32 applied apply VBN cord-022526-j9kg00qf 3654 33 to to IN cord-022526-j9kg00qf 3654 34 blood blood NN cord-022526-j9kg00qf 3654 35 or or CC cord-022526-j9kg00qf 3654 36 feces fece NNS cord-022526-j9kg00qf 3654 37 . . . cord-022526-j9kg00qf 3655 1 [ [ -LRB- cord-022526-j9kg00qf 3655 2 73 73 CD cord-022526-j9kg00qf 3655 3 ] ] -RRB- cord-022526-j9kg00qf 3655 4 [ [ -LRB- cord-022526-j9kg00qf 3655 5 74 74 CD cord-022526-j9kg00qf 3655 6 ] ] -RRB- cord-022526-j9kg00qf 3655 7 [ [ -LRB- cord-022526-j9kg00qf 3655 8 75 75 CD cord-022526-j9kg00qf 3655 9 ] ] -RRB- cord-022526-j9kg00qf 3655 10 Prevention Prevention NNP cord-022526-j9kg00qf 3655 11 Prevention Prevention NNP cord-022526-j9kg00qf 3655 12 of of IN cord-022526-j9kg00qf 3655 13 the the DT cord-022526-j9kg00qf 3655 14 disease disease NN cord-022526-j9kg00qf 3655 15 by by IN cord-022526-j9kg00qf 3655 16 reducing reduce VBG cord-022526-j9kg00qf 3655 17 exposure exposure NN cord-022526-j9kg00qf 3655 18 to to IN cord-022526-j9kg00qf 3655 19 the the DT cord-022526-j9kg00qf 3655 20 causative causative JJ cord-022526-j9kg00qf 3655 21 organism organism NN cord-022526-j9kg00qf 3655 22 is be VBZ cord-022526-j9kg00qf 3655 23 difficult difficult JJ cord-022526-j9kg00qf 3655 24 because because IN cord-022526-j9kg00qf 3655 25 the the DT cord-022526-j9kg00qf 3655 26 mode mode NN cord-022526-j9kg00qf 3655 27 of of IN cord-022526-j9kg00qf 3655 28 transmission transmission NN cord-022526-j9kg00qf 3655 29 is be VBZ cord-022526-j9kg00qf 3655 30 not not RB cord-022526-j9kg00qf 3655 31 known know VBN cord-022526-j9kg00qf 3655 32 . . . cord-022526-j9kg00qf 3656 1 A a DT cord-022526-j9kg00qf 3656 2 killed kill VBN cord-022526-j9kg00qf 3656 3 vaccine vaccine NN cord-022526-j9kg00qf 3656 4 has have VBZ cord-022526-j9kg00qf 3656 5 been be VBN cord-022526-j9kg00qf 3656 6 developed develop VBN cord-022526-j9kg00qf 3656 7 that that WDT cord-022526-j9kg00qf 3656 8 is be VBZ cord-022526-j9kg00qf 3656 9 effective effective JJ cord-022526-j9kg00qf 3656 10 in in IN cord-022526-j9kg00qf 3656 11 preventing prevent VBG cord-022526-j9kg00qf 3656 12 clinical clinical JJ cord-022526-j9kg00qf 3656 13 illness illness NN cord-022526-j9kg00qf 3656 14 other other JJ cord-022526-j9kg00qf 3656 15 than than IN cord-022526-j9kg00qf 3656 16 fever fever NN cord-022526-j9kg00qf 3656 17 in in IN cord-022526-j9kg00qf 3656 18 80 80 CD cord-022526-j9kg00qf 3656 19 % % NN cord-022526-j9kg00qf 3656 20 of of IN cord-022526-j9kg00qf 3656 21 experimentally experimentally RB cord-022526-j9kg00qf 3656 22 challenged challenge VBN cord-022526-j9kg00qf 3656 23 horses horse NNS cord-022526-j9kg00qf 3656 24 using use VBG cord-022526-j9kg00qf 3656 25 the the DT cord-022526-j9kg00qf 3656 26 vaccine vaccine NN cord-022526-j9kg00qf 3656 27 strain strain NN cord-022526-j9kg00qf 3656 28 . . . cord-022526-j9kg00qf 3657 1 However however RB cord-022526-j9kg00qf 3657 2 , , , cord-022526-j9kg00qf 3657 3 field field NN cord-022526-j9kg00qf 3657 4 studies study NNS cord-022526-j9kg00qf 3657 5 suggest suggest VBP cord-022526-j9kg00qf 3657 6 the the DT cord-022526-j9kg00qf 3657 7 vaccine vaccine NN cord-022526-j9kg00qf 3657 8 has have VBZ cord-022526-j9kg00qf 3657 9 limited limit VBN cord-022526-j9kg00qf 3657 10 benefit benefit NN cord-022526-j9kg00qf 3657 11 for for IN cord-022526-j9kg00qf 3657 12 prevention prevention NN cord-022526-j9kg00qf 3657 13 or or CC cord-022526-j9kg00qf 3657 14 decreasing decrease VBG cord-022526-j9kg00qf 3657 15 the the DT cord-022526-j9kg00qf 3657 16 severity severity NN cord-022526-j9kg00qf 3657 17 of of IN cord-022526-j9kg00qf 3657 18 natural natural JJ cord-022526-j9kg00qf 3657 19 infection infection NN cord-022526-j9kg00qf 3657 20 . . . cord-022526-j9kg00qf 3658 1 Vaccine vaccine NN cord-022526-j9kg00qf 3658 2 failures failure NNS cord-022526-j9kg00qf 3658 3 have have VBP cord-022526-j9kg00qf 3658 4 been be VBN cord-022526-j9kg00qf 3658 5 attributed attribute VBN cord-022526-j9kg00qf 3658 6 to to TO cord-022526-j9kg00qf 3658 7 strain strain VB cord-022526-j9kg00qf 3658 8 differences difference NNS cord-022526-j9kg00qf 3658 9 in in IN cord-022526-j9kg00qf 3658 10 antigenicity antigenicity NN cord-022526-j9kg00qf 3658 11 or or CC cord-022526-j9kg00qf 3658 12 to to IN cord-022526-j9kg00qf 3658 13 poor poor JJ cord-022526-j9kg00qf 3658 14 antibody antibody NN cord-022526-j9kg00qf 3658 15 responses response NNS cord-022526-j9kg00qf 3658 16 to to IN cord-022526-j9kg00qf 3658 17 the the DT cord-022526-j9kg00qf 3658 18 vaccine vaccine NN cord-022526-j9kg00qf 3658 19 . . . cord-022526-j9kg00qf 3659 1 76 76 CD cord-022526-j9kg00qf 3659 2 , , , cord-022526-j9kg00qf 3659 3 77 77 CD cord-022526-j9kg00qf 3659 4 _SP cord-022526-j9kg00qf 3660 1 Clostridiosis Clostridiosis NNP cord-022526-j9kg00qf 3660 2 is be VBZ cord-022526-j9kg00qf 3660 3 an an DT cord-022526-j9kg00qf 3660 4 important important JJ cord-022526-j9kg00qf 3660 5 cause cause NN cord-022526-j9kg00qf 3660 6 of of IN cord-022526-j9kg00qf 3660 7 acute acute JJ cord-022526-j9kg00qf 3660 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3660 9 in in IN cord-022526-j9kg00qf 3660 10 foals foal NNS cord-022526-j9kg00qf 3660 11 and and CC cord-022526-j9kg00qf 3660 12 adult adult NN cord-022526-j9kg00qf 3660 13 horses horse NNS cord-022526-j9kg00qf 3660 14 . . . cord-022526-j9kg00qf 3661 1 Clostridium clostridium NN cord-022526-j9kg00qf 3661 2 perfringens perfringen NNS cord-022526-j9kg00qf 3661 3 and and CC cord-022526-j9kg00qf 3661 4 C. C. NNP cord-022526-j9kg00qf 3661 5 difficile difficile NN cord-022526-j9kg00qf 3661 6 are be VBP cord-022526-j9kg00qf 3661 7 associated associate VBN cord-022526-j9kg00qf 3661 8 most most RBS cord-022526-j9kg00qf 3661 9 commonly commonly RB cord-022526-j9kg00qf 3661 10 with with IN cord-022526-j9kg00qf 3661 11 intestinal intestinal JJ cord-022526-j9kg00qf 3661 12 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3661 13 in in IN cord-022526-j9kg00qf 3661 14 horses horse NNS cord-022526-j9kg00qf 3661 15 , , , cord-022526-j9kg00qf 3661 16 but but CC cord-022526-j9kg00qf 3661 17 other other JJ cord-022526-j9kg00qf 3661 18 clostridial clostridial JJ cord-022526-j9kg00qf 3661 19 species specie NNS cord-022526-j9kg00qf 3661 20 , , , cord-022526-j9kg00qf 3661 21 including include VBG cord-022526-j9kg00qf 3661 22 C. C. NNP cord-022526-j9kg00qf 3661 23 septicum septicum NNP cord-022526-j9kg00qf 3661 24 , , , cord-022526-j9kg00qf 3661 25 C. C. NNP cord-022526-j9kg00qf 3661 26 cadaveris cadaveris NNP cord-022526-j9kg00qf 3661 27 , , , cord-022526-j9kg00qf 3661 28 and and CC cord-022526-j9kg00qf 3661 29 C. C. NNP cord-022526-j9kg00qf 3661 30 sordellii sordellii NN cord-022526-j9kg00qf 3661 31 also also RB cord-022526-j9kg00qf 3661 32 have have VBP cord-022526-j9kg00qf 3661 33 been be VBN cord-022526-j9kg00qf 3661 34 isolated isolate VBN cord-022526-j9kg00qf 3661 35 from from IN cord-022526-j9kg00qf 3661 36 horses horse NNS cord-022526-j9kg00qf 3661 37 with with IN cord-022526-j9kg00qf 3661 38 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3661 39 . . . cord-022526-j9kg00qf 3662 1 [ [ -LRB- cord-022526-j9kg00qf 3662 2 78 78 CD cord-022526-j9kg00qf 3662 3 ] ] -RRB- cord-022526-j9kg00qf 3662 4 [ [ -LRB- cord-022526-j9kg00qf 3662 5 79 79 CD cord-022526-j9kg00qf 3662 6 ] ] -RRB- cord-022526-j9kg00qf 3663 1 [ [ -LRB- cord-022526-j9kg00qf 3663 2 80 80 CD cord-022526-j9kg00qf 3663 3 ] ] -RRB- cord-022526-j9kg00qf 3664 1 [ [ -LRB- cord-022526-j9kg00qf 3664 2 81 81 CD cord-022526-j9kg00qf 3664 3 ] ] -RRB- cord-022526-j9kg00qf 3665 1 [ [ -LRB- cord-022526-j9kg00qf 3665 2 82 82 CD cord-022526-j9kg00qf 3665 3 ] ] -RRB- cord-022526-j9kg00qf 3666 1 [ [ -LRB- cord-022526-j9kg00qf 3666 2 83 83 CD cord-022526-j9kg00qf 3666 3 ] ] -RRB- cord-022526-j9kg00qf 3667 1 In in IN cord-022526-j9kg00qf 3667 2 horses horse NNS cord-022526-j9kg00qf 3667 3 of of IN cord-022526-j9kg00qf 3667 4 all all DT cord-022526-j9kg00qf 3667 5 ages age NNS cord-022526-j9kg00qf 3667 6 , , , cord-022526-j9kg00qf 3667 7 clostridial clostridial JJ cord-022526-j9kg00qf 3667 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3667 9 appears appear VBZ cord-022526-j9kg00qf 3667 10 to to TO cord-022526-j9kg00qf 3667 11 be be VB cord-022526-j9kg00qf 3667 12 a a DT cord-022526-j9kg00qf 3667 13 common common JJ cord-022526-j9kg00qf 3667 14 antibiotic antibiotic NN cord-022526-j9kg00qf 3667 15 - - HYPH cord-022526-j9kg00qf 3667 16 associated associate VBN cord-022526-j9kg00qf 3667 17 and and CC cord-022526-j9kg00qf 3667 18 nosocomial nosocomial JJ cord-022526-j9kg00qf 3667 19 cause cause NN cord-022526-j9kg00qf 3667 20 of of IN cord-022526-j9kg00qf 3667 21 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3667 22 . . . cord-022526-j9kg00qf 3668 1 82 82 CD cord-022526-j9kg00qf 3668 2 , , , cord-022526-j9kg00qf 3668 3 84 84 CD cord-022526-j9kg00qf 3668 4 , , , cord-022526-j9kg00qf 3668 5 85 85 CD cord-022526-j9kg00qf 3668 6 However however RB cord-022526-j9kg00qf 3668 7 , , , cord-022526-j9kg00qf 3668 8 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3668 9 in in IN cord-022526-j9kg00qf 3668 10 neonatal neonatal JJ cord-022526-j9kg00qf 3668 11 foals foal NNS cord-022526-j9kg00qf 3668 12 is be VBZ cord-022526-j9kg00qf 3668 13 a a DT cord-022526-j9kg00qf 3668 14 distinct distinct JJ cord-022526-j9kg00qf 3668 15 clinical clinical JJ cord-022526-j9kg00qf 3668 16 entity entity NN cord-022526-j9kg00qf 3668 17 and and CC cord-022526-j9kg00qf 3668 18 is be VBZ cord-022526-j9kg00qf 3668 19 discussed discuss VBN cord-022526-j9kg00qf 3668 20 in in IN cord-022526-j9kg00qf 3668 21 more more JJR cord-022526-j9kg00qf 3668 22 detail detail NN cord-022526-j9kg00qf 3668 23 elsewhere elsewhere RB cord-022526-j9kg00qf 3668 24 . . . cord-022526-j9kg00qf 3669 1 This this DT cord-022526-j9kg00qf 3669 2 chapter chapter NN cord-022526-j9kg00qf 3669 3 focuses focus VBZ cord-022526-j9kg00qf 3669 4 on on IN cord-022526-j9kg00qf 3669 5 adult adult NN cord-022526-j9kg00qf 3669 6 intestinal intestinal JJ cord-022526-j9kg00qf 3669 7 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3669 8 . . . cord-022526-j9kg00qf 3670 1 Clostridia Clostridia NNP cord-022526-j9kg00qf 3670 2 are be VBP cord-022526-j9kg00qf 3670 3 obligate obligate VBN cord-022526-j9kg00qf 3670 4 anaerobic anaerobic JJ cord-022526-j9kg00qf 3670 5 to to IN cord-022526-j9kg00qf 3670 6 aerotolerant aerotolerant JJ cord-022526-j9kg00qf 3670 7 spore spore NN cord-022526-j9kg00qf 3670 8 - - HYPH cord-022526-j9kg00qf 3670 9 forming form VBG cord-022526-j9kg00qf 3670 10 gram gram NN cord-022526-j9kg00qf 3670 11 - - HYPH cord-022526-j9kg00qf 3670 12 positive positive JJ cord-022526-j9kg00qf 3670 13 rods rod NNS cord-022526-j9kg00qf 3670 14 that that WDT cord-022526-j9kg00qf 3670 15 are be VBP cord-022526-j9kg00qf 3670 16 ubiquitous ubiquitous JJ cord-022526-j9kg00qf 3670 17 in in IN cord-022526-j9kg00qf 3670 18 the the DT cord-022526-j9kg00qf 3670 19 environment environment NN cord-022526-j9kg00qf 3670 20 in in IN cord-022526-j9kg00qf 3670 21 the the DT cord-022526-j9kg00qf 3670 22 spore spore NN cord-022526-j9kg00qf 3670 23 form form NN cord-022526-j9kg00qf 3670 24 . . . cord-022526-j9kg00qf 3671 1 83 83 CD cord-022526-j9kg00qf 3671 2 Clostridia Clostridia NNP cord-022526-j9kg00qf 3671 3 are be VBP cord-022526-j9kg00qf 3671 4 elements element NNS cord-022526-j9kg00qf 3671 5 of of IN cord-022526-j9kg00qf 3671 6 the the DT cord-022526-j9kg00qf 3671 7 normal normal JJ cord-022526-j9kg00qf 3671 8 flora flora NNS cord-022526-j9kg00qf 3671 9 of of IN cord-022526-j9kg00qf 3671 10 horses horse NNS cord-022526-j9kg00qf 3671 11 of of IN cord-022526-j9kg00qf 3671 12 all all DT cord-022526-j9kg00qf 3671 13 ages age NNS cord-022526-j9kg00qf 3671 14 and and CC cord-022526-j9kg00qf 3671 15 are be VBP cord-022526-j9kg00qf 3671 16 among among IN cord-022526-j9kg00qf 3671 17 the the DT cord-022526-j9kg00qf 3671 18 first first JJ cord-022526-j9kg00qf 3671 19 bacteria bacteria NNS cord-022526-j9kg00qf 3671 20 acquired acquire VBN cord-022526-j9kg00qf 3671 21 after after IN cord-022526-j9kg00qf 3671 22 birth birth NN cord-022526-j9kg00qf 3671 23 . . . cord-022526-j9kg00qf 3672 1 However however RB cord-022526-j9kg00qf 3672 2 , , , cord-022526-j9kg00qf 3672 3 clostridia clostridia NNP cord-022526-j9kg00qf 3672 4 inhabiting inhabit VBG cord-022526-j9kg00qf 3672 5 the the DT cord-022526-j9kg00qf 3672 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3672 7 tract tract NN cord-022526-j9kg00qf 3672 8 normally normally RB cord-022526-j9kg00qf 3672 9 are be VBP cord-022526-j9kg00qf 3672 10 found find VBN cord-022526-j9kg00qf 3672 11 in in IN cord-022526-j9kg00qf 3672 12 low low JJ cord-022526-j9kg00qf 3672 13 numbers number NNS cord-022526-j9kg00qf 3672 14 and and CC cord-022526-j9kg00qf 3672 15 do do VBP cord-022526-j9kg00qf 3672 16 not not RB cord-022526-j9kg00qf 3672 17 produce produce VB cord-022526-j9kg00qf 3672 18 enterotoxins enterotoxin NNS cord-022526-j9kg00qf 3672 19 . . . cord-022526-j9kg00qf 3673 1 Clostridiosis Clostridiosis NNP cord-022526-j9kg00qf 3673 2 is be VBZ cord-022526-j9kg00qf 3673 3 associated associate VBN cord-022526-j9kg00qf 3673 4 with with IN cord-022526-j9kg00qf 3673 5 an an DT cord-022526-j9kg00qf 3673 6 increase increase NN cord-022526-j9kg00qf 3673 7 in in IN cord-022526-j9kg00qf 3673 8 the the DT cord-022526-j9kg00qf 3673 9 number number NN cord-022526-j9kg00qf 3673 10 of of IN cord-022526-j9kg00qf 3673 11 a a DT cord-022526-j9kg00qf 3673 12 particular particular JJ cord-022526-j9kg00qf 3673 13 species species NN cord-022526-j9kg00qf 3673 14 of of IN cord-022526-j9kg00qf 3673 15 clostridia clostridium NNS cord-022526-j9kg00qf 3673 16 in in IN cord-022526-j9kg00qf 3673 17 the the DT cord-022526-j9kg00qf 3673 18 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3673 19 tract tract NN cord-022526-j9kg00qf 3673 20 and and CC cord-022526-j9kg00qf 3673 21 , , , cord-022526-j9kg00qf 3673 22 perhaps perhaps RB cord-022526-j9kg00qf 3673 23 most most RBS cord-022526-j9kg00qf 3673 24 importantly importantly RB cord-022526-j9kg00qf 3673 25 , , , cord-022526-j9kg00qf 3673 26 exotoxin exotoxin NN cord-022526-j9kg00qf 3673 27 production production NN cord-022526-j9kg00qf 3673 28 . . . cord-022526-j9kg00qf 3674 1 Although although IN cord-022526-j9kg00qf 3674 2 the the DT cord-022526-j9kg00qf 3674 3 conditions condition NNS cord-022526-j9kg00qf 3674 4 resulting result VBG cord-022526-j9kg00qf 3674 5 in in IN cord-022526-j9kg00qf 3674 6 exotoxin exotoxin NN cord-022526-j9kg00qf 3674 7 production production NN cord-022526-j9kg00qf 3674 8 are be VBP cord-022526-j9kg00qf 3674 9 not not RB cord-022526-j9kg00qf 3674 10 understood understand VBN cord-022526-j9kg00qf 3674 11 fully fully RB cord-022526-j9kg00qf 3674 12 , , , cord-022526-j9kg00qf 3674 13 several several JJ cord-022526-j9kg00qf 3674 14 factors factor NNS cord-022526-j9kg00qf 3674 15 increase increase VBP cord-022526-j9kg00qf 3674 16 clostridial clostridial JJ cord-022526-j9kg00qf 3674 17 numbers number NNS cord-022526-j9kg00qf 3674 18 in in IN cord-022526-j9kg00qf 3674 19 the the DT cord-022526-j9kg00qf 3674 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3674 21 tract tract NN cord-022526-j9kg00qf 3674 22 . . . cord-022526-j9kg00qf 3675 1 Dietary dietary JJ cord-022526-j9kg00qf 3675 2 factors factor NNS cord-022526-j9kg00qf 3675 3 are be VBP cord-022526-j9kg00qf 3675 4 known know VBN cord-022526-j9kg00qf 3675 5 to to TO cord-022526-j9kg00qf 3675 6 affect affect VB cord-022526-j9kg00qf 3675 7 the the DT cord-022526-j9kg00qf 3675 8 numbers number NNS cord-022526-j9kg00qf 3675 9 of of IN cord-022526-j9kg00qf 3675 10 Clostridium clostridium NN cord-022526-j9kg00qf 3675 11 species specie NNS cord-022526-j9kg00qf 3675 12 shed shed VBN cord-022526-j9kg00qf 3675 13 in in IN cord-022526-j9kg00qf 3675 14 the the DT cord-022526-j9kg00qf 3675 15 horse horse NN cord-022526-j9kg00qf 3675 16 feces fece NNS cord-022526-j9kg00qf 3675 17 . . . cord-022526-j9kg00qf 3676 1 78 78 CD cord-022526-j9kg00qf 3676 2 Experimental experimental JJ cord-022526-j9kg00qf 3676 3 induction induction NN cord-022526-j9kg00qf 3676 4 of of IN cord-022526-j9kg00qf 3676 5 colic colic NN cord-022526-j9kg00qf 3676 6 increases increase VBZ cord-022526-j9kg00qf 3676 7 fecal fecal JJ cord-022526-j9kg00qf 3676 8 shedding shedding NN cord-022526-j9kg00qf 3676 9 of of IN cord-022526-j9kg00qf 3676 10 Clostridium clostridium NN cord-022526-j9kg00qf 3676 11 species specie NNS cord-022526-j9kg00qf 3676 12 in in IN cord-022526-j9kg00qf 3676 13 the the DT cord-022526-j9kg00qf 3676 14 absence absence NN cord-022526-j9kg00qf 3676 15 of of IN cord-022526-j9kg00qf 3676 16 diarrhea diarrhea NN cord-022526-j9kg00qf 3676 17 . . . cord-022526-j9kg00qf 3677 1 86 86 CD cord-022526-j9kg00qf 3677 2 Antibiotics antibiotic NNS cord-022526-j9kg00qf 3677 3 , , , cord-022526-j9kg00qf 3677 4 particularly particularly RB cord-022526-j9kg00qf 3677 5 administered administer VBN cord-022526-j9kg00qf 3677 6 orally orally RB cord-022526-j9kg00qf 3677 7 or or CC cord-022526-j9kg00qf 3677 8 recycled recycle VBN cord-022526-j9kg00qf 3677 9 via via IN cord-022526-j9kg00qf 3677 10 the the DT cord-022526-j9kg00qf 3677 11 enterohepatic enterohepatic JJ cord-022526-j9kg00qf 3677 12 system system NN cord-022526-j9kg00qf 3677 13 , , , cord-022526-j9kg00qf 3677 14 are be VBP cord-022526-j9kg00qf 3677 15 well well RB cord-022526-j9kg00qf 3677 16 documented document VBN cord-022526-j9kg00qf 3677 17 to to TO cord-022526-j9kg00qf 3677 18 increase increase VB cord-022526-j9kg00qf 3677 19 the the DT cord-022526-j9kg00qf 3677 20 recovery recovery NN cord-022526-j9kg00qf 3677 21 of of IN cord-022526-j9kg00qf 3677 22 clostridia clostridia NNP cord-022526-j9kg00qf 3677 23 colony colony NN cord-022526-j9kg00qf 3677 24 - - HYPH cord-022526-j9kg00qf 3677 25 forming form VBG cord-022526-j9kg00qf 3677 26 units unit NNS cord-022526-j9kg00qf 3677 27 ( ( -LRB- cord-022526-j9kg00qf 3677 28 CFUs CFUs NNP cord-022526-j9kg00qf 3677 29 ) ) -RRB- cord-022526-j9kg00qf 3677 30 in in IN cord-022526-j9kg00qf 3677 31 equine equine JJ cord-022526-j9kg00qf 3677 32 feces fece NNS cord-022526-j9kg00qf 3677 33 and and CC cord-022526-j9kg00qf 3677 34 may may MD cord-022526-j9kg00qf 3677 35 result result VB cord-022526-j9kg00qf 3677 36 in in IN cord-022526-j9kg00qf 3677 37 clinical clinical JJ cord-022526-j9kg00qf 3677 38 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3677 39 . . . cord-022526-j9kg00qf 3678 1 79 79 CD cord-022526-j9kg00qf 3678 2 , , , cord-022526-j9kg00qf 3678 3 81 81 CD cord-022526-j9kg00qf 3678 4 , , , cord-022526-j9kg00qf 3678 5 [ [ -LRB- cord-022526-j9kg00qf 3678 6 87 87 CD cord-022526-j9kg00qf 3678 7 ] ] -RRB- cord-022526-j9kg00qf 3679 1 [ [ -LRB- cord-022526-j9kg00qf 3679 2 88 88 CD cord-022526-j9kg00qf 3679 3 ] ] -RRB- cord-022526-j9kg00qf 3680 1 [ [ -LRB- cord-022526-j9kg00qf 3680 2 89 89 CD cord-022526-j9kg00qf 3680 3 ] ] -RRB- cord-022526-j9kg00qf 3681 1 [ [ -LRB- cord-022526-j9kg00qf 3681 2 90 90 CD cord-022526-j9kg00qf 3681 3 ] ] -RRB- cord-022526-j9kg00qf 3682 1 Indeed indeed RB cord-022526-j9kg00qf 3682 2 , , , cord-022526-j9kg00qf 3682 3 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3682 4 associated associate VBN cord-022526-j9kg00qf 3682 5 with with IN cord-022526-j9kg00qf 3682 6 C. C. NNP cord-022526-j9kg00qf 3682 7 perfringens perfringen NNS cord-022526-j9kg00qf 3682 8 or or CC cord-022526-j9kg00qf 3682 9 C. C. NNP cord-022526-j9kg00qf 3682 10 difficile difficile NNP cord-022526-j9kg00qf 3682 11 is be VBZ cord-022526-j9kg00qf 3682 12 likely likely JJ cord-022526-j9kg00qf 3682 13 to to TO cord-022526-j9kg00qf 3682 14 be be VB cord-022526-j9kg00qf 3682 15 the the DT cord-022526-j9kg00qf 3682 16 most most RBS cord-022526-j9kg00qf 3682 17 important important JJ cord-022526-j9kg00qf 3682 18 cause cause NN cord-022526-j9kg00qf 3682 19 of of IN cord-022526-j9kg00qf 3682 20 antibiotic antibiotic NN cord-022526-j9kg00qf 3682 21 - - HYPH cord-022526-j9kg00qf 3682 22 induced induce VBN cord-022526-j9kg00qf 3682 23 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3682 24 in in IN cord-022526-j9kg00qf 3682 25 the the DT cord-022526-j9kg00qf 3682 26 horse horse NN cord-022526-j9kg00qf 3682 27 . . . cord-022526-j9kg00qf 3683 1 Clostridium clostridium NN cord-022526-j9kg00qf 3683 2 perfringens perfringen VBZ cord-022526-j9kg00qf 3683 3 C. C. NNP cord-022526-j9kg00qf 3683 4 perfringens perfringen NNS cord-022526-j9kg00qf 3683 5 is be VBZ cord-022526-j9kg00qf 3683 6 made make VBN cord-022526-j9kg00qf 3683 7 up up RP cord-022526-j9kg00qf 3683 8 of of IN cord-022526-j9kg00qf 3683 9 many many JJ cord-022526-j9kg00qf 3683 10 genetically genetically RB cord-022526-j9kg00qf 3683 11 distinct distinct JJ cord-022526-j9kg00qf 3683 12 strains strain NNS cord-022526-j9kg00qf 3683 13 of of IN cord-022526-j9kg00qf 3683 14 variable variable JJ cord-022526-j9kg00qf 3683 15 virulence virulence NN cord-022526-j9kg00qf 3683 16 that that WDT cord-022526-j9kg00qf 3683 17 produce produce VBP cord-022526-j9kg00qf 3683 18 one one CD cord-022526-j9kg00qf 3683 19 or or CC cord-022526-j9kg00qf 3683 20 more more JJR cord-022526-j9kg00qf 3683 21 of of IN cord-022526-j9kg00qf 3683 22 a a DT cord-022526-j9kg00qf 3683 23 large large JJ cord-022526-j9kg00qf 3683 24 group group NN cord-022526-j9kg00qf 3683 25 of of IN cord-022526-j9kg00qf 3683 26 exotoxins exotoxin NNS cord-022526-j9kg00qf 3683 27 . . . cord-022526-j9kg00qf 3684 1 The the DT cord-022526-j9kg00qf 3684 2 pattern pattern NN cord-022526-j9kg00qf 3684 3 of of IN cord-022526-j9kg00qf 3684 4 exotoxin exotoxin NN cord-022526-j9kg00qf 3684 5 production production NN cord-022526-j9kg00qf 3684 6 is be VBZ cord-022526-j9kg00qf 3684 7 used use VBN cord-022526-j9kg00qf 3684 8 to to TO cord-022526-j9kg00qf 3684 9 classify classify VB cord-022526-j9kg00qf 3684 10 C. C. NNP cord-022526-j9kg00qf 3684 11 perfringens perfringen NNS cord-022526-j9kg00qf 3684 12 into into IN cord-022526-j9kg00qf 3684 13 five five CD cord-022526-j9kg00qf 3684 14 types type NNS cord-022526-j9kg00qf 3684 15 , , , cord-022526-j9kg00qf 3684 16 A A NNP cord-022526-j9kg00qf 3684 17 , , , cord-022526-j9kg00qf 3684 18 B B NNP cord-022526-j9kg00qf 3684 19 , , , cord-022526-j9kg00qf 3684 20 C C NNP cord-022526-j9kg00qf 3684 21 , , , cord-022526-j9kg00qf 3684 22 D D NNP cord-022526-j9kg00qf 3684 23 , , , cord-022526-j9kg00qf 3684 24 and and CC cord-022526-j9kg00qf 3685 1 E. E. NNP cord-022526-j9kg00qf 3685 2 C. C. NNP cord-022526-j9kg00qf 3685 3 perfringens perfringens NN cord-022526-j9kg00qf 3685 4 type type NN cord-022526-j9kg00qf 3685 5 A a NN cord-022526-j9kg00qf 3685 6 is be VBZ cord-022526-j9kg00qf 3685 7 the the DT cord-022526-j9kg00qf 3685 8 most most RBS cord-022526-j9kg00qf 3685 9 common common JJ cord-022526-j9kg00qf 3685 10 clostridium clostridium NN cord-022526-j9kg00qf 3685 11 isolate isolate VBP cord-022526-j9kg00qf 3685 12 from from IN cord-022526-j9kg00qf 3685 13 healthy healthy JJ cord-022526-j9kg00qf 3685 14 horses horse NNS cord-022526-j9kg00qf 3685 15 of of IN cord-022526-j9kg00qf 3685 16 all all DT cord-022526-j9kg00qf 3685 17 ages age NNS cord-022526-j9kg00qf 3685 18 and and CC cord-022526-j9kg00qf 3685 19 adults adult NNS cord-022526-j9kg00qf 3685 20 and and CC cord-022526-j9kg00qf 3685 21 foals foal NNS cord-022526-j9kg00qf 3685 22 with with IN cord-022526-j9kg00qf 3685 23 diarrhea diarrhea NN cord-022526-j9kg00qf 3685 24 worldwide worldwide RB cord-022526-j9kg00qf 3685 25 . . . cord-022526-j9kg00qf 3686 1 C. C. NNP cord-022526-j9kg00qf 3686 2 perfringens perfringen VBZ cord-022526-j9kg00qf 3686 3 types type NNS cord-022526-j9kg00qf 3687 1 A a LS cord-022526-j9kg00qf 3687 2 , , , cord-022526-j9kg00qf 3687 3 B B NNP cord-022526-j9kg00qf 3687 4 , , , cord-022526-j9kg00qf 3687 5 C C NNP cord-022526-j9kg00qf 3687 6 , , , cord-022526-j9kg00qf 3687 7 and and CC cord-022526-j9kg00qf 3687 8 D D NNP cord-022526-j9kg00qf 3687 9 have have VBP cord-022526-j9kg00qf 3687 10 been be VBN cord-022526-j9kg00qf 3687 11 associated associate VBN cord-022526-j9kg00qf 3687 12 with with IN cord-022526-j9kg00qf 3687 13 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 3687 14 enteritis enteritis NN cord-022526-j9kg00qf 3687 15 in in IN cord-022526-j9kg00qf 3687 16 foals foal NNS cord-022526-j9kg00qf 3687 17 less less JJR cord-022526-j9kg00qf 3687 18 than than IN cord-022526-j9kg00qf 3687 19 10 10 CD cord-022526-j9kg00qf 3687 20 days day NNS cord-022526-j9kg00qf 3687 21 of of IN cord-022526-j9kg00qf 3687 22 age age NN cord-022526-j9kg00qf 3687 23 , , , cord-022526-j9kg00qf 3687 24 with with IN cord-022526-j9kg00qf 3687 25 type type NN cord-022526-j9kg00qf 3687 26 C c NN cord-022526-j9kg00qf 3687 27 being be VBG cord-022526-j9kg00qf 3687 28 the the DT cord-022526-j9kg00qf 3687 29 most most RBS cord-022526-j9kg00qf 3687 30 common common JJ cord-022526-j9kg00qf 3687 31 cause cause NN cord-022526-j9kg00qf 3687 32 in in IN cord-022526-j9kg00qf 3687 33 North North NNP cord-022526-j9kg00qf 3687 34 America America NNP cord-022526-j9kg00qf 3687 35 . . . cord-022526-j9kg00qf 3688 1 The the DT cord-022526-j9kg00qf 3688 2 primary primary JJ cord-022526-j9kg00qf 3688 3 toxin toxin NN cord-022526-j9kg00qf 3688 4 produced produce VBN cord-022526-j9kg00qf 3688 5 by by IN cord-022526-j9kg00qf 3688 6 C. C. NNP cord-022526-j9kg00qf 3688 7 perfringens perfringens NN cord-022526-j9kg00qf 3688 8 type type NN cord-022526-j9kg00qf 3688 9 A a NN cord-022526-j9kg00qf 3688 10 is be VBZ cord-022526-j9kg00qf 3688 11 α α NN cord-022526-j9kg00qf 3688 12 - - HYPH cord-022526-j9kg00qf 3688 13 toxin toxin NN cord-022526-j9kg00qf 3688 14 ( ( -LRB- cord-022526-j9kg00qf 3688 15 phospholipase phospholipase NN cord-022526-j9kg00qf 3688 16 C C NNP cord-022526-j9kg00qf 3688 17 ) ) -RRB- cord-022526-j9kg00qf 3688 18 , , , cord-022526-j9kg00qf 3688 19 which which WDT cord-022526-j9kg00qf 3688 20 interferes interfere VBZ cord-022526-j9kg00qf 3688 21 with with IN cord-022526-j9kg00qf 3688 22 glucose glucose NN cord-022526-j9kg00qf 3688 23 uptake uptake NN cord-022526-j9kg00qf 3688 24 and and CC cord-022526-j9kg00qf 3688 25 energy energy NN cord-022526-j9kg00qf 3688 26 production production NN cord-022526-j9kg00qf 3688 27 and and CC cord-022526-j9kg00qf 3688 28 activates activate VBZ cord-022526-j9kg00qf 3688 29 arachidonic arachidonic JJ cord-022526-j9kg00qf 3688 30 acid acid NN cord-022526-j9kg00qf 3688 31 metabolism metabolism NN cord-022526-j9kg00qf 3688 32 and and CC cord-022526-j9kg00qf 3688 33 signaling signal VBG cord-022526-j9kg00qf 3688 34 pathways pathway NNS cord-022526-j9kg00qf 3688 35 in in IN cord-022526-j9kg00qf 3688 36 enterocytes enterocyte NNS cord-022526-j9kg00qf 3688 37 . . . cord-022526-j9kg00qf 3689 1 83 83 CD cord-022526-j9kg00qf 3689 2 Oral oral JJ cord-022526-j9kg00qf 3689 3 administration administration NN cord-022526-j9kg00qf 3689 4 of of IN cord-022526-j9kg00qf 3689 5 α α NN cord-022526-j9kg00qf 3689 6 - - HYPH cord-022526-j9kg00qf 3689 7 toxin toxin NN cord-022526-j9kg00qf 3689 8 does do VBZ cord-022526-j9kg00qf 3689 9 not not RB cord-022526-j9kg00qf 3689 10 cause cause VB cord-022526-j9kg00qf 3689 11 tissue tissue NN cord-022526-j9kg00qf 3689 12 necrosis necrosis NN cord-022526-j9kg00qf 3689 13 but but CC cord-022526-j9kg00qf 3689 14 causes cause NNS cord-022526-j9kg00qf 3689 15 increased increase VBN cord-022526-j9kg00qf 3689 16 secretion secretion NN cord-022526-j9kg00qf 3689 17 by by IN cord-022526-j9kg00qf 3689 18 small small JJ cord-022526-j9kg00qf 3689 19 intestinal intestinal JJ cord-022526-j9kg00qf 3689 20 mucosal mucosal JJ cord-022526-j9kg00qf 3689 21 cells cell NNS cord-022526-j9kg00qf 3689 22 in in IN cord-022526-j9kg00qf 3689 23 human human JJ cord-022526-j9kg00qf 3689 24 beings being NNS cord-022526-j9kg00qf 3689 25 . . . cord-022526-j9kg00qf 3690 1 91 91 CD cord-022526-j9kg00qf 3690 2 , , , cord-022526-j9kg00qf 3690 3 92 92 CD cord-022526-j9kg00qf 3691 1 The the DT cord-022526-j9kg00qf 3691 2 β β NN cord-022526-j9kg00qf 3691 3 - - HYPH cord-022526-j9kg00qf 3691 4 toxin toxin NN cord-022526-j9kg00qf 3691 5 of of IN cord-022526-j9kg00qf 3691 6 types type NNS cord-022526-j9kg00qf 3691 7 B b NN cord-022526-j9kg00qf 3691 8 and and CC cord-022526-j9kg00qf 3691 9 C C NNP cord-022526-j9kg00qf 3691 10 is be VBZ cord-022526-j9kg00qf 3691 11 a a DT cord-022526-j9kg00qf 3691 12 cytotoxin cytotoxin NN cord-022526-j9kg00qf 3691 13 that that WDT cord-022526-j9kg00qf 3691 14 causes cause VBZ cord-022526-j9kg00qf 3691 15 enterocyte enterocyte NNP cord-022526-j9kg00qf 3691 16 necrosis necrosis NN cord-022526-j9kg00qf 3691 17 , , , cord-022526-j9kg00qf 3691 18 ulceration ulceration NN cord-022526-j9kg00qf 3691 19 , , , cord-022526-j9kg00qf 3691 20 and and CC cord-022526-j9kg00qf 3691 21 ultimately ultimately RB cord-022526-j9kg00qf 3691 22 severe severe JJ cord-022526-j9kg00qf 3691 23 intestinal intestinal JJ cord-022526-j9kg00qf 3691 24 inflammation inflammation NN cord-022526-j9kg00qf 3691 25 and and CC cord-022526-j9kg00qf 3691 26 hemorrhage hemorrhage NN cord-022526-j9kg00qf 3691 27 . . . cord-022526-j9kg00qf 3692 1 93 93 CD cord-022526-j9kg00qf 3693 1 A a DT cord-022526-j9kg00qf 3693 2 novel novel JJ cord-022526-j9kg00qf 3693 3 toxin toxin NN cord-022526-j9kg00qf 3693 4 designated designate VBN cord-022526-j9kg00qf 3693 5 β2 β2 NN cord-022526-j9kg00qf 3693 6 may may MD cord-022526-j9kg00qf 3693 7 also also RB cord-022526-j9kg00qf 3693 8 have have VB cord-022526-j9kg00qf 3693 9 a a DT cord-022526-j9kg00qf 3693 10 role role NN cord-022526-j9kg00qf 3693 11 in in IN cord-022526-j9kg00qf 3693 12 C. C. NNP cord-022526-j9kg00qf 3693 13 perfringens perfringens NN cord-022526-j9kg00qf 3693 14 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3693 15 . . . cord-022526-j9kg00qf 3694 1 94 94 CD cord-022526-j9kg00qf 3695 1 The the DT cord-022526-j9kg00qf 3695 2 biologic biologic JJ cord-022526-j9kg00qf 3695 3 activity activity NN cord-022526-j9kg00qf 3695 4 of of IN cord-022526-j9kg00qf 3695 5 the the DT cord-022526-j9kg00qf 3695 6 β2-toxin β2-toxin NNP cord-022526-j9kg00qf 3695 7 is be VBZ cord-022526-j9kg00qf 3695 8 similar similar JJ cord-022526-j9kg00qf 3695 9 to to IN cord-022526-j9kg00qf 3695 10 β β NN cord-022526-j9kg00qf 3695 11 - - HYPH cord-022526-j9kg00qf 3695 12 toxin toxin NN cord-022526-j9kg00qf 3695 13 , , , cord-022526-j9kg00qf 3695 14 but but CC cord-022526-j9kg00qf 3695 15 β2-toxin β2-toxin NNP cord-022526-j9kg00qf 3695 16 is be VBZ cord-022526-j9kg00qf 3695 17 not not RB cord-022526-j9kg00qf 3695 18 related relate VBN cord-022526-j9kg00qf 3695 19 to to IN cord-022526-j9kg00qf 3695 20 β β NN cord-022526-j9kg00qf 3695 21 - - HYPH cord-022526-j9kg00qf 3695 22 toxin toxin NN cord-022526-j9kg00qf 3695 23 in in IN cord-022526-j9kg00qf 3695 24 sequence sequence NN cord-022526-j9kg00qf 3695 25 . . . cord-022526-j9kg00qf 3696 1 The the DT cord-022526-j9kg00qf 3696 2 β2-toxin β2-toxin NN cord-022526-j9kg00qf 3696 3 was be VBD cord-022526-j9kg00qf 3696 4 prevalent prevalent JJ cord-022526-j9kg00qf 3696 5 in in IN cord-022526-j9kg00qf 3696 6 two two CD cord-022526-j9kg00qf 3696 7 groups group NNS cord-022526-j9kg00qf 3696 8 of of IN cord-022526-j9kg00qf 3696 9 horses horse NNS cord-022526-j9kg00qf 3696 10 with with IN cord-022526-j9kg00qf 3696 11 acute acute JJ cord-022526-j9kg00qf 3696 12 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3696 13 but but CC cord-022526-j9kg00qf 3696 14 not not RB cord-022526-j9kg00qf 3696 15 in in IN cord-022526-j9kg00qf 3696 16 healthy healthy JJ cord-022526-j9kg00qf 3696 17 horses horse NNS cord-022526-j9kg00qf 3696 18 . . . cord-022526-j9kg00qf 3697 1 95 95 CD cord-022526-j9kg00qf 3698 1 The the DT cord-022526-j9kg00qf 3698 2 β2-toxin β2-toxin NN cord-022526-j9kg00qf 3698 3 appears appear VBZ cord-022526-j9kg00qf 3698 4 to to TO cord-022526-j9kg00qf 3698 5 be be VB cord-022526-j9kg00qf 3698 6 associated associate VBN cord-022526-j9kg00qf 3698 7 predominantly predominantly RB cord-022526-j9kg00qf 3698 8 with with IN cord-022526-j9kg00qf 3698 9 C. C. NNP cord-022526-j9kg00qf 3698 10 perfringens perfringen NNS cord-022526-j9kg00qf 3698 11 that that WDT cord-022526-j9kg00qf 3698 12 would would MD cord-022526-j9kg00qf 3698 13 have have VB cord-022526-j9kg00qf 3698 14 been be VBN cord-022526-j9kg00qf 3698 15 classified classify VBN cord-022526-j9kg00qf 3698 16 otherwise otherwise RB cord-022526-j9kg00qf 3698 17 as as IN cord-022526-j9kg00qf 3698 18 type type NN cord-022526-j9kg00qf 3698 19 A a NN cord-022526-j9kg00qf 3698 20 but but CC cord-022526-j9kg00qf 3698 21 that that IN cord-022526-j9kg00qf 3698 22 in in IN cord-022526-j9kg00qf 3698 23 fact fact NN cord-022526-j9kg00qf 3698 24 may may MD cord-022526-j9kg00qf 3698 25 represent represent VB cord-022526-j9kg00qf 3698 26 a a DT cord-022526-j9kg00qf 3698 27 previously previously RB cord-022526-j9kg00qf 3698 28 undescribed undescribed JJ cord-022526-j9kg00qf 3698 29 type type NN cord-022526-j9kg00qf 3698 30 . . . cord-022526-j9kg00qf 3699 1 Virulent virulent JJ cord-022526-j9kg00qf 3699 2 strains strain NNS cord-022526-j9kg00qf 3699 3 of of IN cord-022526-j9kg00qf 3699 4 C. C. NNP cord-022526-j9kg00qf 3699 5 perfringens perfringens NN cord-022526-j9kg00qf 3699 6 type type NN cord-022526-j9kg00qf 3699 7 A a NN cord-022526-j9kg00qf 3699 8 and and CC cord-022526-j9kg00qf 3699 9 to to IN cord-022526-j9kg00qf 3699 10 a a DT cord-022526-j9kg00qf 3699 11 lesser less JJR cord-022526-j9kg00qf 3699 12 extent extent NN cord-022526-j9kg00qf 3699 13 type type NN cord-022526-j9kg00qf 3699 14 C C NNP cord-022526-j9kg00qf 3699 15 also also RB cord-022526-j9kg00qf 3699 16 may may MD cord-022526-j9kg00qf 3699 17 produce produce VB cord-022526-j9kg00qf 3699 18 enterotoxin enterotoxin NN cord-022526-j9kg00qf 3699 19 . . . cord-022526-j9kg00qf 3700 1 Enterotoxin Enterotoxin NNP cord-022526-j9kg00qf 3700 2 is be VBZ cord-022526-j9kg00qf 3700 3 a a DT cord-022526-j9kg00qf 3700 4 cytotoxin cytotoxin NN cord-022526-j9kg00qf 3700 5 that that WDT cord-022526-j9kg00qf 3700 6 inserts insert VBZ cord-022526-j9kg00qf 3700 7 into into IN cord-022526-j9kg00qf 3700 8 cell cell NN cord-022526-j9kg00qf 3700 9 membranes membrane NNS cord-022526-j9kg00qf 3700 10 to to TO cord-022526-j9kg00qf 3700 11 form form VB cord-022526-j9kg00qf 3700 12 pores pore NNS cord-022526-j9kg00qf 3700 13 , , , cord-022526-j9kg00qf 3700 14 which which WDT cord-022526-j9kg00qf 3700 15 alter alter VBP cord-022526-j9kg00qf 3700 16 permeability permeability NN cord-022526-j9kg00qf 3700 17 to to IN cord-022526-j9kg00qf 3700 18 water water NN cord-022526-j9kg00qf 3700 19 and and CC cord-022526-j9kg00qf 3700 20 macromolecules macromolecule NNS cord-022526-j9kg00qf 3700 21 and and CC cord-022526-j9kg00qf 3700 22 ultimately ultimately RB cord-022526-j9kg00qf 3700 23 lead lead VBP cord-022526-j9kg00qf 3700 24 to to IN cord-022526-j9kg00qf 3700 25 cellular cellular JJ cord-022526-j9kg00qf 3700 26 necrosis necrosis NN cord-022526-j9kg00qf 3700 27 . . . cord-022526-j9kg00qf 3701 1 96 96 CD cord-022526-j9kg00qf 3701 2 Massive massive JJ cord-022526-j9kg00qf 3701 3 desquamation desquamation NN cord-022526-j9kg00qf 3701 4 of of IN cord-022526-j9kg00qf 3701 5 the the DT cord-022526-j9kg00qf 3701 6 intestinal intestinal JJ cord-022526-j9kg00qf 3701 7 mucosa mucosa NN cord-022526-j9kg00qf 3701 8 resulting result VBG cord-022526-j9kg00qf 3701 9 from from IN cord-022526-j9kg00qf 3701 10 enterotoxin enterotoxin JJ cord-022526-j9kg00qf 3701 11 cytotoxicity cytotoxicity NN cord-022526-j9kg00qf 3701 12 triggers trigger VBZ cord-022526-j9kg00qf 3701 13 an an DT cord-022526-j9kg00qf 3701 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 3701 15 response response NN cord-022526-j9kg00qf 3701 16 , , , cord-022526-j9kg00qf 3701 17 intestinal intestinal JJ cord-022526-j9kg00qf 3701 18 edema edema NN cord-022526-j9kg00qf 3701 19 , , , cord-022526-j9kg00qf 3701 20 mural mural NN cord-022526-j9kg00qf 3701 21 hemorrhage hemorrhage NN cord-022526-j9kg00qf 3701 22 , , , cord-022526-j9kg00qf 3701 23 and and CC cord-022526-j9kg00qf 3701 24 systemic systemic JJ cord-022526-j9kg00qf 3701 25 inflammation inflammation NN cord-022526-j9kg00qf 3701 26 . . . cord-022526-j9kg00qf 3702 1 97 97 CD cord-022526-j9kg00qf 3703 1 Enterotoxin Enterotoxin NNP cord-022526-j9kg00qf 3703 2 also also RB cord-022526-j9kg00qf 3703 3 alters alter VBZ cord-022526-j9kg00qf 3703 4 tight tight JJ cord-022526-j9kg00qf 3703 5 junction junction NN cord-022526-j9kg00qf 3703 6 integrity integrity NN cord-022526-j9kg00qf 3703 7 , , , cord-022526-j9kg00qf 3703 8 resulting result VBG cord-022526-j9kg00qf 3703 9 in in IN cord-022526-j9kg00qf 3703 10 increased increase VBN cord-022526-j9kg00qf 3703 11 paracellular paracellular JJ cord-022526-j9kg00qf 3703 12 permeability permeability NN cord-022526-j9kg00qf 3703 13 by by IN cord-022526-j9kg00qf 3703 14 a a DT cord-022526-j9kg00qf 3703 15 noncytotoxic noncytotoxic NN cord-022526-j9kg00qf 3703 16 mechanism mechanism NN cord-022526-j9kg00qf 3703 17 . . . cord-022526-j9kg00qf 3704 1 98 98 CD cord-022526-j9kg00qf 3704 2 Clostridium clostridium NN cord-022526-j9kg00qf 3704 3 difficile difficile NN cord-022526-j9kg00qf 3704 4 C. c. NN cord-022526-j9kg00qf 3704 5 difficile difficile NN cord-022526-j9kg00qf 3704 6 produces produce VBZ cord-022526-j9kg00qf 3704 7 several several JJ cord-022526-j9kg00qf 3704 8 toxins toxin NNS cord-022526-j9kg00qf 3704 9 , , , cord-022526-j9kg00qf 3704 10 but but CC cord-022526-j9kg00qf 3704 11 only only RB cord-022526-j9kg00qf 3704 12 two two CD cord-022526-j9kg00qf 3704 13 , , , cord-022526-j9kg00qf 3704 14 toxin toxin NN cord-022526-j9kg00qf 3704 15 A a NN cord-022526-j9kg00qf 3704 16 and and CC cord-022526-j9kg00qf 3704 17 toxin toxin NN cord-022526-j9kg00qf 3704 18 B b NN cord-022526-j9kg00qf 3704 19 have have VBP cord-022526-j9kg00qf 3704 20 been be VBN cord-022526-j9kg00qf 3704 21 studied study VBN cord-022526-j9kg00qf 3704 22 in in IN cord-022526-j9kg00qf 3704 23 detail detail NN cord-022526-j9kg00qf 3704 24 . . . cord-022526-j9kg00qf 3705 1 Toxin toxin NN cord-022526-j9kg00qf 3705 2 B B NNP cord-022526-j9kg00qf 3705 3 is be VBZ cord-022526-j9kg00qf 3705 4 a a DT cord-022526-j9kg00qf 3705 5 potent potent JJ cord-022526-j9kg00qf 3705 6 cytotoxin cytotoxin NN cord-022526-j9kg00qf 3705 7 in in IN cord-022526-j9kg00qf 3705 8 vitro vitro FW cord-022526-j9kg00qf 3705 9 , , , cord-022526-j9kg00qf 3705 10 but but CC cord-022526-j9kg00qf 3705 11 its -PRON- PRP$ cord-022526-j9kg00qf 3705 12 role role NN cord-022526-j9kg00qf 3705 13 in in IN cord-022526-j9kg00qf 3705 14 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3705 15 is be VBZ cord-022526-j9kg00qf 3705 16 less less RBR cord-022526-j9kg00qf 3705 17 clear clear JJ cord-022526-j9kg00qf 3705 18 than than IN cord-022526-j9kg00qf 3705 19 the the DT cord-022526-j9kg00qf 3705 20 role role NN cord-022526-j9kg00qf 3705 21 of of IN cord-022526-j9kg00qf 3705 22 toxin toxin NN cord-022526-j9kg00qf 3705 23 A. a. NN cord-022526-j9kg00qf 3705 24 Toxin toxin NN cord-022526-j9kg00qf 3705 25 B B NNP cord-022526-j9kg00qf 3705 26 does do VBZ cord-022526-j9kg00qf 3705 27 not not RB cord-022526-j9kg00qf 3705 28 induce induce VB cord-022526-j9kg00qf 3705 29 fluid fluid JJ cord-022526-j9kg00qf 3705 30 secretion secretion NN cord-022526-j9kg00qf 3705 31 , , , cord-022526-j9kg00qf 3705 32 inflammation inflammation NN cord-022526-j9kg00qf 3705 33 , , , cord-022526-j9kg00qf 3705 34 or or CC cord-022526-j9kg00qf 3705 35 characteristic characteristic JJ cord-022526-j9kg00qf 3705 36 alterations alteration NNS cord-022526-j9kg00qf 3705 37 in in IN cord-022526-j9kg00qf 3705 38 intestinal intestinal JJ cord-022526-j9kg00qf 3705 39 morphology morphology NN cord-022526-j9kg00qf 3705 40 . . . cord-022526-j9kg00qf 3706 1 C. C. NNP cord-022526-j9kg00qf 3706 2 difficile difficile NNP cord-022526-j9kg00qf 3706 3 induces induce VBZ cord-022526-j9kg00qf 3706 4 an an DT cord-022526-j9kg00qf 3706 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 3706 6 response response NN cord-022526-j9kg00qf 3706 7 with with IN cord-022526-j9kg00qf 3706 8 hypersecretory hypersecretory NNP cord-022526-j9kg00qf 3706 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3706 10 that that WDT cord-022526-j9kg00qf 3706 11 is be VBZ cord-022526-j9kg00qf 3706 12 induced induce VBN cord-022526-j9kg00qf 3706 13 in in IN cord-022526-j9kg00qf 3706 14 large large JJ cord-022526-j9kg00qf 3706 15 part part NN cord-022526-j9kg00qf 3706 16 by by IN cord-022526-j9kg00qf 3706 17 the the DT cord-022526-j9kg00qf 3706 18 enterotoxin enterotoxin JJ cord-022526-j9kg00qf 3706 19 toxin toxin NN cord-022526-j9kg00qf 3706 20 A. a. NN cord-022526-j9kg00qf 3707 1 99 99 CD cord-022526-j9kg00qf 3707 2 Toxin toxin NN cord-022526-j9kg00qf 3707 3 A a NN cord-022526-j9kg00qf 3707 4 induces induce VBZ cord-022526-j9kg00qf 3707 5 neutrophil neutrophil NN cord-022526-j9kg00qf 3707 6 influx influx NN cord-022526-j9kg00qf 3707 7 into into IN cord-022526-j9kg00qf 3707 8 intestinal intestinal JJ cord-022526-j9kg00qf 3707 9 tissue tissue NN cord-022526-j9kg00qf 3707 10 , , , cord-022526-j9kg00qf 3707 11 mast mast NN cord-022526-j9kg00qf 3707 12 cell cell NN cord-022526-j9kg00qf 3707 13 degranulation degranulation NN cord-022526-j9kg00qf 3707 14 , , , cord-022526-j9kg00qf 3707 15 and and CC cord-022526-j9kg00qf 3707 16 secretion secretion NN cord-022526-j9kg00qf 3707 17 of of IN cord-022526-j9kg00qf 3707 18 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 3707 19 , , , cord-022526-j9kg00qf 3707 20 histamine histamine NN cord-022526-j9kg00qf 3707 21 , , , cord-022526-j9kg00qf 3707 22 cytokines cytokine NNS cord-022526-j9kg00qf 3707 23 , , , cord-022526-j9kg00qf 3707 24 and and CC cord-022526-j9kg00qf 3707 25 5-hydroxytryptamine 5-hydroxytryptamine CD cord-022526-j9kg00qf 3707 26 by by IN cord-022526-j9kg00qf 3707 27 these these DT cord-022526-j9kg00qf 3707 28 activated activate VBN cord-022526-j9kg00qf 3707 29 leukocytes leukocyte NNS cord-022526-j9kg00qf 3707 30 . . . cord-022526-j9kg00qf 3708 1 100 100 CD cord-022526-j9kg00qf 3708 2 , , , cord-022526-j9kg00qf 3708 3 101 101 CD cord-022526-j9kg00qf 3709 1 The the DT cord-022526-j9kg00qf 3709 2 products product NNS cord-022526-j9kg00qf 3709 3 of of IN cord-022526-j9kg00qf 3709 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 3709 5 and and CC cord-022526-j9kg00qf 3709 6 mast mast NN cord-022526-j9kg00qf 3709 7 cells cell NNS cord-022526-j9kg00qf 3709 8 have have VBP cord-022526-j9kg00qf 3709 9 a a DT cord-022526-j9kg00qf 3709 10 prominent prominent JJ cord-022526-j9kg00qf 3709 11 role role NN cord-022526-j9kg00qf 3709 12 in in IN cord-022526-j9kg00qf 3709 13 the the DT cord-022526-j9kg00qf 3709 14 vasodilatory vasodilatory NN cord-022526-j9kg00qf 3709 15 and and CC cord-022526-j9kg00qf 3709 16 secretory secretory JJ cord-022526-j9kg00qf 3709 17 responses response NNS cord-022526-j9kg00qf 3709 18 in in IN cord-022526-j9kg00qf 3709 19 the the DT cord-022526-j9kg00qf 3709 20 intestine intestine NN cord-022526-j9kg00qf 3709 21 during during IN cord-022526-j9kg00qf 3709 22 C. C. NNP cord-022526-j9kg00qf 3709 23 difficile difficile NN cord-022526-j9kg00qf 3709 24 infection infection NN cord-022526-j9kg00qf 3709 25 . . . cord-022526-j9kg00qf 3710 1 The the DT cord-022526-j9kg00qf 3710 2 enteric enteric JJ cord-022526-j9kg00qf 3710 3 nervous nervous JJ cord-022526-j9kg00qf 3710 4 system system NN cord-022526-j9kg00qf 3710 5 is be VBZ cord-022526-j9kg00qf 3710 6 central central JJ cord-022526-j9kg00qf 3710 7 to to IN cord-022526-j9kg00qf 3710 8 the the DT cord-022526-j9kg00qf 3710 9 induction induction NN cord-022526-j9kg00qf 3710 10 of of IN cord-022526-j9kg00qf 3710 11 intestinal intestinal JJ cord-022526-j9kg00qf 3710 12 inflammation inflammation NN cord-022526-j9kg00qf 3710 13 and and CC cord-022526-j9kg00qf 3710 14 mucosal mucosal JJ cord-022526-j9kg00qf 3710 15 secretion secretion NN cord-022526-j9kg00qf 3710 16 by by IN cord-022526-j9kg00qf 3710 17 toxin toxin NN cord-022526-j9kg00qf 3710 18 A. a. NN cord-022526-j9kg00qf 3710 19 A A NNP cord-022526-j9kg00qf 3710 20 model model NN cord-022526-j9kg00qf 3710 21 for for IN cord-022526-j9kg00qf 3710 22 toxin toxin NN cord-022526-j9kg00qf 3710 23 A a NN cord-022526-j9kg00qf 3710 24 - - HYPH cord-022526-j9kg00qf 3710 25 induced induce VBN cord-022526-j9kg00qf 3710 26 secretory secretory JJ cord-022526-j9kg00qf 3710 27 diarrhea diarrhea NN cord-022526-j9kg00qf 3710 28 has have VBZ cord-022526-j9kg00qf 3710 29 emerged emerge VBN cord-022526-j9kg00qf 3710 30 in in IN cord-022526-j9kg00qf 3710 31 which which WDT cord-022526-j9kg00qf 3710 32 toxin toxin NN cord-022526-j9kg00qf 3710 33 A a NN cord-022526-j9kg00qf 3710 34 stimulates stimulate VBZ cord-022526-j9kg00qf 3710 35 substance substance NN cord-022526-j9kg00qf 3710 36 P p NN cord-022526-j9kg00qf 3710 37 - - HYPH cord-022526-j9kg00qf 3710 38 containing contain VBG cord-022526-j9kg00qf 3710 39 afferent afferent JJ cord-022526-j9kg00qf 3710 40 sensory sensory JJ cord-022526-j9kg00qf 3710 41 nerve nerve NN cord-022526-j9kg00qf 3710 42 fibers fiber NNS cord-022526-j9kg00qf 3710 43 , , , cord-022526-j9kg00qf 3710 44 which which WDT cord-022526-j9kg00qf 3710 45 in in IN cord-022526-j9kg00qf 3710 46 turn turn NN cord-022526-j9kg00qf 3710 47 stimulate stimulate VBP cord-022526-j9kg00qf 3710 48 mast mast JJ cord-022526-j9kg00qf 3710 49 cell cell NN cord-022526-j9kg00qf 3710 50 degranulation degranulation NN cord-022526-j9kg00qf 3710 51 , , , cord-022526-j9kg00qf 3710 52 recruitment recruitment NN cord-022526-j9kg00qf 3710 53 and and CC cord-022526-j9kg00qf 3710 54 activation activation NN cord-022526-j9kg00qf 3710 55 of of IN cord-022526-j9kg00qf 3710 56 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 3710 57 leukocytes leukocyte NNS cord-022526-j9kg00qf 3710 58 , , , cord-022526-j9kg00qf 3710 59 and and CC cord-022526-j9kg00qf 3710 60 vasodilation vasodilation NN cord-022526-j9kg00qf 3710 61 . . . cord-022526-j9kg00qf 3711 1 [ [ -LRB- cord-022526-j9kg00qf 3711 2 102 102 CD cord-022526-j9kg00qf 3711 3 ] ] -RRB- cord-022526-j9kg00qf 3711 4 [ [ -LRB- cord-022526-j9kg00qf 3711 5 103 103 CD cord-022526-j9kg00qf 3711 6 ] ] -RRB- cord-022526-j9kg00qf 3711 7 [ [ -LRB- cord-022526-j9kg00qf 3711 8 104 104 CD cord-022526-j9kg00qf 3711 9 ] ] -RRB- cord-022526-j9kg00qf 3711 10 Toxin toxin NN cord-022526-j9kg00qf 3711 11 A a NN cord-022526-j9kg00qf 3711 12 - - HYPH cord-022526-j9kg00qf 3711 13 induced induce VBN cord-022526-j9kg00qf 3711 14 stimulation stimulation NN cord-022526-j9kg00qf 3711 15 of of IN cord-022526-j9kg00qf 3711 16 enterocyte enterocyte NNP cord-022526-j9kg00qf 3711 17 secretion secretion NN cord-022526-j9kg00qf 3711 18 can can MD cord-022526-j9kg00qf 3711 19 occur occur VB cord-022526-j9kg00qf 3711 20 via via IN cord-022526-j9kg00qf 3711 21 secretomotor secretomotor NN cord-022526-j9kg00qf 3711 22 neuronal neuronal JJ cord-022526-j9kg00qf 3711 23 stimulation stimulation NN cord-022526-j9kg00qf 3711 24 by by IN cord-022526-j9kg00qf 3711 25 substance substance NN cord-022526-j9kg00qf 3711 26 P p NN cord-022526-j9kg00qf 3711 27 - - HYPH cord-022526-j9kg00qf 3711 28 containing contain VBG cord-022526-j9kg00qf 3711 29 sensory sensory JJ cord-022526-j9kg00qf 3711 30 neurons neuron NNS cord-022526-j9kg00qf 3711 31 or or CC cord-022526-j9kg00qf 3711 32 products product NNS cord-022526-j9kg00qf 3711 33 of of IN cord-022526-j9kg00qf 3711 34 mast mast NN cord-022526-j9kg00qf 3711 35 cells cell NNS cord-022526-j9kg00qf 3711 36 and and CC cord-022526-j9kg00qf 3711 37 polymorphonuclear polymorphonuclear NN cord-022526-j9kg00qf 3711 38 leukocytes leukocyte NNS cord-022526-j9kg00qf 3711 39 . . . cord-022526-j9kg00qf 3712 1 Neural neural JJ cord-022526-j9kg00qf 3712 2 blockade blockade NN cord-022526-j9kg00qf 3712 3 or or CC cord-022526-j9kg00qf 3712 4 depletion depletion NN cord-022526-j9kg00qf 3712 5 of of IN cord-022526-j9kg00qf 3712 6 substance substance NN cord-022526-j9kg00qf 3712 7 P p NN cord-022526-j9kg00qf 3712 8 abolishes abolish VBZ cord-022526-j9kg00qf 3712 9 mast mast JJ cord-022526-j9kg00qf 3712 10 cell cell NN cord-022526-j9kg00qf 3712 11 degranulation degranulation NN cord-022526-j9kg00qf 3712 12 , , , cord-022526-j9kg00qf 3712 13 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 3712 14 leukocyte leukocyte NN cord-022526-j9kg00qf 3712 15 influx influx NN cord-022526-j9kg00qf 3712 16 , , , cord-022526-j9kg00qf 3712 17 and and CC cord-022526-j9kg00qf 3712 18 enterocyte enterocyte NNP cord-022526-j9kg00qf 3712 19 secretion secretion NN cord-022526-j9kg00qf 3712 20 . . . cord-022526-j9kg00qf 3713 1 How how WRB cord-022526-j9kg00qf 3713 2 toxin toxin NN cord-022526-j9kg00qf 3713 3 A a DT cord-022526-j9kg00qf 3713 4 triggers trigger VBZ cord-022526-j9kg00qf 3713 5 the the DT cord-022526-j9kg00qf 3713 6 sensory sensory JJ cord-022526-j9kg00qf 3713 7 component component NN cord-022526-j9kg00qf 3713 8 of of IN cord-022526-j9kg00qf 3713 9 the the DT cord-022526-j9kg00qf 3713 10 enteric enteric JJ cord-022526-j9kg00qf 3713 11 nervous nervous JJ cord-022526-j9kg00qf 3713 12 system system NN cord-022526-j9kg00qf 3713 13 is be VBZ cord-022526-j9kg00qf 3713 14 not not RB cord-022526-j9kg00qf 3713 15 known know VBN cord-022526-j9kg00qf 3713 16 yet yet RB cord-022526-j9kg00qf 3713 17 , , , cord-022526-j9kg00qf 3713 18 but but CC cord-022526-j9kg00qf 3713 19 toxin toxin NN cord-022526-j9kg00qf 3713 20 A a NN cord-022526-j9kg00qf 3713 21 - - HYPH cord-022526-j9kg00qf 3713 22 induced induce VBN cord-022526-j9kg00qf 3713 23 necrosis necrosis NN cord-022526-j9kg00qf 3713 24 of of IN cord-022526-j9kg00qf 3713 25 enterocytes enterocytes NNP cord-022526-j9kg00qf 3713 26 likely likely RB cord-022526-j9kg00qf 3713 27 exposes expose VBZ cord-022526-j9kg00qf 3713 28 afferent afferent JJ cord-022526-j9kg00qf 3713 29 neurons neuron NNS cord-022526-j9kg00qf 3713 30 to to IN cord-022526-j9kg00qf 3713 31 the the DT cord-022526-j9kg00qf 3713 32 noxious noxious JJ cord-022526-j9kg00qf 3713 33 milieu milieu NN cord-022526-j9kg00qf 3713 34 of of IN cord-022526-j9kg00qf 3713 35 the the DT cord-022526-j9kg00qf 3713 36 intestinal intestinal JJ cord-022526-j9kg00qf 3713 37 contents content NNS cord-022526-j9kg00qf 3713 38 . . . cord-022526-j9kg00qf 3714 1 Equine equine JJ cord-022526-j9kg00qf 3714 2 intestinal intestinal JJ cord-022526-j9kg00qf 3714 3 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3714 4 is be VBZ cord-022526-j9kg00qf 3714 5 clinically clinically RB cord-022526-j9kg00qf 3714 6 similar similar JJ cord-022526-j9kg00qf 3714 7 to to IN cord-022526-j9kg00qf 3714 8 other other JJ cord-022526-j9kg00qf 3714 9 forms form NNS cord-022526-j9kg00qf 3714 10 of of IN cord-022526-j9kg00qf 3714 11 acute acute JJ cord-022526-j9kg00qf 3714 12 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3714 13 in in IN cord-022526-j9kg00qf 3714 14 horses horse NNS cord-022526-j9kg00qf 3714 15 . . . cord-022526-j9kg00qf 3715 1 78 78 CD cord-022526-j9kg00qf 3715 2 , , , cord-022526-j9kg00qf 3715 3 83 83 CD cord-022526-j9kg00qf 3716 1 Although although IN cord-022526-j9kg00qf 3716 2 the the DT cord-022526-j9kg00qf 3716 3 clinical clinical JJ cord-022526-j9kg00qf 3716 4 course course NN cord-022526-j9kg00qf 3716 5 is be VBZ cord-022526-j9kg00qf 3716 6 usually usually RB cord-022526-j9kg00qf 3716 7 acute acute JJ cord-022526-j9kg00qf 3716 8 , , , cord-022526-j9kg00qf 3716 9 peracute peracute NN cord-022526-j9kg00qf 3716 10 colitis colitis NN cord-022526-j9kg00qf 3716 11 with with IN cord-022526-j9kg00qf 3716 12 rapid rapid JJ cord-022526-j9kg00qf 3716 13 death death NN cord-022526-j9kg00qf 3716 14 may may MD cord-022526-j9kg00qf 3716 15 occur occur VB cord-022526-j9kg00qf 3716 16 . . . cord-022526-j9kg00qf 3717 1 Occasionally occasionally RB cord-022526-j9kg00qf 3717 2 , , , cord-022526-j9kg00qf 3717 3 a a DT cord-022526-j9kg00qf 3717 4 milder mild JJR cord-022526-j9kg00qf 3717 5 , , , cord-022526-j9kg00qf 3717 6 more more RBR cord-022526-j9kg00qf 3717 7 prolonged prolonged JJ cord-022526-j9kg00qf 3717 8 clinical clinical JJ cord-022526-j9kg00qf 3717 9 course course NN cord-022526-j9kg00qf 3717 10 occurs occur VBZ cord-022526-j9kg00qf 3717 11 . . . cord-022526-j9kg00qf 3718 1 One one CD cord-022526-j9kg00qf 3718 2 may may MD cord-022526-j9kg00qf 3718 3 note note VB cord-022526-j9kg00qf 3718 4 fever fever NN cord-022526-j9kg00qf 3718 5 , , , cord-022526-j9kg00qf 3718 6 anorexia anorexia NN cord-022526-j9kg00qf 3718 7 , , , cord-022526-j9kg00qf 3718 8 and and CC cord-022526-j9kg00qf 3718 9 depression depression NN cord-022526-j9kg00qf 3718 10 before before IN cord-022526-j9kg00qf 3718 11 the the DT cord-022526-j9kg00qf 3718 12 onset onset NN cord-022526-j9kg00qf 3718 13 of of IN cord-022526-j9kg00qf 3718 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3718 15 signs sign NNS cord-022526-j9kg00qf 3718 16 , , , cord-022526-j9kg00qf 3718 17 but but CC cord-022526-j9kg00qf 3718 18 more more RBR cord-022526-j9kg00qf 3718 19 commonly commonly RB cord-022526-j9kg00qf 3718 20 no no DT cord-022526-j9kg00qf 3718 21 prodromal prodromal JJ cord-022526-j9kg00qf 3718 22 signs sign NNS cord-022526-j9kg00qf 3718 23 are be VBP cord-022526-j9kg00qf 3718 24 apparent apparent JJ cord-022526-j9kg00qf 3718 25 . . . cord-022526-j9kg00qf 3719 1 Signs sign NNS cord-022526-j9kg00qf 3719 2 of of IN cord-022526-j9kg00qf 3719 3 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3719 4 and and CC cord-022526-j9kg00qf 3719 5 shock shock NN cord-022526-j9kg00qf 3719 6 may may MD cord-022526-j9kg00qf 3719 7 accompany accompany VB cord-022526-j9kg00qf 3719 8 acute acute JJ cord-022526-j9kg00qf 3719 9 signs sign NNS cord-022526-j9kg00qf 3719 10 of of IN cord-022526-j9kg00qf 3719 11 colic colic NN cord-022526-j9kg00qf 3719 12 and and CC cord-022526-j9kg00qf 3719 13 severe severe JJ cord-022526-j9kg00qf 3719 14 , , , cord-022526-j9kg00qf 3719 15 dehydrating dehydrate VBG cord-022526-j9kg00qf 3719 16 diarrhea diarrhea NN cord-022526-j9kg00qf 3719 17 . . . cord-022526-j9kg00qf 3720 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3720 2 may may MD cord-022526-j9kg00qf 3720 3 not not RB cord-022526-j9kg00qf 3720 4 be be VB cord-022526-j9kg00qf 3720 5 profuse profuse JJ cord-022526-j9kg00qf 3720 6 but but CC cord-022526-j9kg00qf 3720 7 is be VBZ cord-022526-j9kg00qf 3720 8 usually usually RB cord-022526-j9kg00qf 3720 9 dark dark JJ cord-022526-j9kg00qf 3720 10 and and CC cord-022526-j9kg00qf 3720 11 foul foul JJ cord-022526-j9kg00qf 3720 12 smelling smelling NN cord-022526-j9kg00qf 3720 13 . . . cord-022526-j9kg00qf 3721 1 Like like IN cord-022526-j9kg00qf 3721 2 the the DT cord-022526-j9kg00qf 3721 3 clinical clinical JJ cord-022526-j9kg00qf 3721 4 signs sign NNS cord-022526-j9kg00qf 3721 5 , , , cord-022526-j9kg00qf 3721 6 hematologic hematologic JJ cord-022526-j9kg00qf 3721 7 and and CC cord-022526-j9kg00qf 3721 8 serum serum JJ cord-022526-j9kg00qf 3721 9 biochemical biochemical JJ cord-022526-j9kg00qf 3721 10 abnormalities abnormality NNS cord-022526-j9kg00qf 3721 11 are be VBP cord-022526-j9kg00qf 3721 12 similar similar JJ cord-022526-j9kg00qf 3721 13 to to IN cord-022526-j9kg00qf 3721 14 those those DT cord-022526-j9kg00qf 3721 15 associated associate VBN cord-022526-j9kg00qf 3721 16 with with IN cord-022526-j9kg00qf 3721 17 other other JJ cord-022526-j9kg00qf 3721 18 forms form NNS cord-022526-j9kg00qf 3721 19 of of IN cord-022526-j9kg00qf 3721 20 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3721 21 and and CC cord-022526-j9kg00qf 3721 22 reflect reflect VBP cord-022526-j9kg00qf 3721 23 fluid fluid NN cord-022526-j9kg00qf 3721 24 , , , cord-022526-j9kg00qf 3721 25 protein protein NN cord-022526-j9kg00qf 3721 26 , , , cord-022526-j9kg00qf 3721 27 and and CC cord-022526-j9kg00qf 3721 28 electrolyte electrolyte JJ cord-022526-j9kg00qf 3721 29 loss loss NN cord-022526-j9kg00qf 3721 30 and and CC cord-022526-j9kg00qf 3721 31 systemic systemic JJ cord-022526-j9kg00qf 3721 32 inflammation inflammation NN cord-022526-j9kg00qf 3721 33 from from IN cord-022526-j9kg00qf 3721 34 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3721 35 . . . cord-022526-j9kg00qf 3722 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 3722 2 , , , cord-022526-j9kg00qf 3722 3 leukopenia leukopenia NN cord-022526-j9kg00qf 3722 4 , , , cord-022526-j9kg00qf 3722 5 and and CC cord-022526-j9kg00qf 3722 6 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 3722 7 are be VBP cord-022526-j9kg00qf 3722 8 common common JJ cord-022526-j9kg00qf 3722 9 . . . cord-022526-j9kg00qf 3723 1 Hypoproteinemia Hypoproteinemia NNP cord-022526-j9kg00qf 3723 2 may may MD cord-022526-j9kg00qf 3723 3 be be VB cord-022526-j9kg00qf 3723 4 profound profound JJ cord-022526-j9kg00qf 3723 5 . . . cord-022526-j9kg00qf 3724 1 One one CD cord-022526-j9kg00qf 3724 2 often often RB cord-022526-j9kg00qf 3724 3 may may MD cord-022526-j9kg00qf 3724 4 note note VB cord-022526-j9kg00qf 3724 5 hyponatremia hyponatremia NN cord-022526-j9kg00qf 3724 6 , , , cord-022526-j9kg00qf 3724 7 hypokalemia hypokalemia NN cord-022526-j9kg00qf 3724 8 , , , cord-022526-j9kg00qf 3724 9 hypochloremia hypochloremia NN cord-022526-j9kg00qf 3724 10 , , , cord-022526-j9kg00qf 3724 11 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 3724 12 , , , cord-022526-j9kg00qf 3724 13 and and CC cord-022526-j9kg00qf 3724 14 a a DT cord-022526-j9kg00qf 3724 15 mixed mixed JJ cord-022526-j9kg00qf 3724 16 prerenal prerenal NNP cord-022526-j9kg00qf 3724 17 / / SYM cord-022526-j9kg00qf 3724 18 renal renal JJ cord-022526-j9kg00qf 3724 19 azotemia azotemia NNP cord-022526-j9kg00qf 3724 20 , , , cord-022526-j9kg00qf 3724 21 as as RB cord-022526-j9kg00qf 3724 22 well well RB cord-022526-j9kg00qf 3724 23 as as IN cord-022526-j9kg00qf 3724 24 metabolic metabolic JJ cord-022526-j9kg00qf 3724 25 acidosis acidosis NN cord-022526-j9kg00qf 3724 26 and and CC cord-022526-j9kg00qf 3724 27 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 3724 28 . . . cord-022526-j9kg00qf 3725 1 Serum serum NN cord-022526-j9kg00qf 3725 2 concentrations concentration NNS cord-022526-j9kg00qf 3725 3 of of IN cord-022526-j9kg00qf 3725 4 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 3725 5 enzymes enzyme NNS cord-022526-j9kg00qf 3725 6 such such JJ cord-022526-j9kg00qf 3725 7 as as IN cord-022526-j9kg00qf 3725 8 sorbitol sorbitol NN cord-022526-j9kg00qf 3725 9 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 3725 10 may may MD cord-022526-j9kg00qf 3725 11 be be VB cord-022526-j9kg00qf 3725 12 elevated elevate VBN cord-022526-j9kg00qf 3725 13 , , , cord-022526-j9kg00qf 3725 14 and and CC cord-022526-j9kg00qf 3725 15 liver liver NN cord-022526-j9kg00qf 3725 16 function function NN cord-022526-j9kg00qf 3725 17 may may MD cord-022526-j9kg00qf 3725 18 be be VB cord-022526-j9kg00qf 3725 19 reduced reduce VBN cord-022526-j9kg00qf 3725 20 . . . cord-022526-j9kg00qf 3726 1 Preliminary preliminary JJ cord-022526-j9kg00qf 3726 2 diagnosis diagnosis NN cord-022526-j9kg00qf 3726 3 of of IN cord-022526-j9kg00qf 3726 4 equine equine JJ cord-022526-j9kg00qf 3726 5 intestinal intestinal JJ cord-022526-j9kg00qf 3726 6 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3726 7 caused cause VBN cord-022526-j9kg00qf 3726 8 by by IN cord-022526-j9kg00qf 3726 9 C. C. NNP cord-022526-j9kg00qf 3726 10 perfringens perfringens NNP cord-022526-j9kg00qf 3726 11 is be VBZ cord-022526-j9kg00qf 3726 12 based base VBN cord-022526-j9kg00qf 3726 13 on on IN cord-022526-j9kg00qf 3726 14 the the DT cord-022526-j9kg00qf 3726 15 isolation isolation NN cord-022526-j9kg00qf 3726 16 of of IN cord-022526-j9kg00qf 3726 17 greater great JJR cord-022526-j9kg00qf 3726 18 than than IN cord-022526-j9kg00qf 3726 19 100 100 CD cord-022526-j9kg00qf 3726 20 CFUs cfu NNS cord-022526-j9kg00qf 3726 21 of of IN cord-022526-j9kg00qf 3726 22 C. C. NNP cord-022526-j9kg00qf 3726 23 perfringens perfringens NN cord-022526-j9kg00qf 3726 24 type type NN cord-022526-j9kg00qf 3726 25 A a NN cord-022526-j9kg00qf 3726 26 per per IN cord-022526-j9kg00qf 3726 27 gram gram NN cord-022526-j9kg00qf 3726 28 of of IN cord-022526-j9kg00qf 3726 29 feces fece NNS cord-022526-j9kg00qf 3726 30 from from IN cord-022526-j9kg00qf 3726 31 patients patient NNS cord-022526-j9kg00qf 3726 32 with with IN cord-022526-j9kg00qf 3726 33 diarrhea diarrhea NN cord-022526-j9kg00qf 3726 34 and and CC cord-022526-j9kg00qf 3726 35 signs sign NNS cord-022526-j9kg00qf 3726 36 suggestive suggestive JJ cord-022526-j9kg00qf 3726 37 of of IN cord-022526-j9kg00qf 3726 38 toxemia toxemia NN cord-022526-j9kg00qf 3726 39 . . . cord-022526-j9kg00qf 3727 1 Similar similar JJ cord-022526-j9kg00qf 3727 2 criteria criterion NNS cord-022526-j9kg00qf 3727 3 are be VBP cord-022526-j9kg00qf 3727 4 used use VBN cord-022526-j9kg00qf 3727 5 to to TO cord-022526-j9kg00qf 3727 6 screen screen VB cord-022526-j9kg00qf 3727 7 human human JJ cord-022526-j9kg00qf 3727 8 patients patient NNS cord-022526-j9kg00qf 3727 9 for for IN cord-022526-j9kg00qf 3727 10 C. C. NNP cord-022526-j9kg00qf 3727 11 perfringens perfringens NN cord-022526-j9kg00qf 3727 12 type type NN cord-022526-j9kg00qf 3727 13 A a DT cord-022526-j9kg00qf 3727 14 infection infection NN cord-022526-j9kg00qf 3727 15 . . . cord-022526-j9kg00qf 3728 1 Normal normal JJ cord-022526-j9kg00qf 3728 2 horses horse NNS cord-022526-j9kg00qf 3728 3 shed shed VBD cord-022526-j9kg00qf 3728 4 fewer few JJR cord-022526-j9kg00qf 3728 5 than than IN cord-022526-j9kg00qf 3728 6 100 100 CD cord-022526-j9kg00qf 3728 7 CFUs cfu NNS cord-022526-j9kg00qf 3728 8 / / SYM cord-022526-j9kg00qf 3728 9 g g NN cord-022526-j9kg00qf 3728 10 of of IN cord-022526-j9kg00qf 3728 11 feces fece NNS cord-022526-j9kg00qf 3728 12 , , , cord-022526-j9kg00qf 3728 13 and and CC cord-022526-j9kg00qf 3728 14 usually usually RB cord-022526-j9kg00qf 3728 15 horses horse NNS cord-022526-j9kg00qf 3728 16 with with IN cord-022526-j9kg00qf 3728 17 intestinal intestinal JJ cord-022526-j9kg00qf 3728 18 clostridiosis clostridiosis NN cord-022526-j9kg00qf 3728 19 shed shed VBD cord-022526-j9kg00qf 3728 20 greater great JJR cord-022526-j9kg00qf 3728 21 than than IN cord-022526-j9kg00qf 3728 22 1 1 CD cord-022526-j9kg00qf 3728 23 × × CD cord-022526-j9kg00qf 3728 24 10 10 CD cord-022526-j9kg00qf 3728 25 6 6 CD cord-022526-j9kg00qf 3729 1 CFUs CFUs NNP cord-022526-j9kg00qf 3729 2 / / SYM cord-022526-j9kg00qf 3729 3 g g NN cord-022526-j9kg00qf 3729 4 . . . cord-022526-j9kg00qf 3730 1 78 78 CD cord-022526-j9kg00qf 3730 2 , , , cord-022526-j9kg00qf 3730 3 105 105 CD cord-022526-j9kg00qf 3731 1 However however RB cord-022526-j9kg00qf 3731 2 , , , cord-022526-j9kg00qf 3731 3 identification identification NN cord-022526-j9kg00qf 3731 4 of of IN cord-022526-j9kg00qf 3731 5 increased increase VBN cord-022526-j9kg00qf 3731 6 numbers number NNS cord-022526-j9kg00qf 3731 7 of of IN cord-022526-j9kg00qf 3731 8 Clostridium clostridium NN cord-022526-j9kg00qf 3731 9 organisms organism NNS cord-022526-j9kg00qf 3731 10 in in IN cord-022526-j9kg00qf 3731 11 the the DT cord-022526-j9kg00qf 3731 12 feces fece NNS cord-022526-j9kg00qf 3731 13 does do VBZ cord-022526-j9kg00qf 3731 14 not not RB cord-022526-j9kg00qf 3731 15 prove prove VB cord-022526-j9kg00qf 3731 16 infection infection NN cord-022526-j9kg00qf 3731 17 . . . cord-022526-j9kg00qf 3732 1 Detection detection NN cord-022526-j9kg00qf 3732 2 of of IN cord-022526-j9kg00qf 3732 3 C. C. NNP cord-022526-j9kg00qf 3732 4 perfringens perfringen VBZ cord-022526-j9kg00qf 3732 5 toxins toxin NNS cord-022526-j9kg00qf 3732 6 in in IN cord-022526-j9kg00qf 3732 7 feces fece NNS cord-022526-j9kg00qf 3732 8 or or CC cord-022526-j9kg00qf 3732 9 intestinal intestinal JJ cord-022526-j9kg00qf 3732 10 contents content NNS cord-022526-j9kg00qf 3732 11 in in IN cord-022526-j9kg00qf 3732 12 horses horse NNS cord-022526-j9kg00qf 3732 13 with with IN cord-022526-j9kg00qf 3732 14 increased increase VBN cord-022526-j9kg00qf 3732 15 numbers number NNS cord-022526-j9kg00qf 3732 16 of of IN cord-022526-j9kg00qf 3732 17 fecal fecal JJ cord-022526-j9kg00qf 3732 18 CFUs cfus NN cord-022526-j9kg00qf 3732 19 and and CC cord-022526-j9kg00qf 3732 20 clinical clinical JJ cord-022526-j9kg00qf 3732 21 signs sign NNS cord-022526-j9kg00qf 3732 22 of of IN cord-022526-j9kg00qf 3732 23 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3732 24 is be VBZ cord-022526-j9kg00qf 3732 25 more more RBR cord-022526-j9kg00qf 3732 26 conclusive conclusive JJ cord-022526-j9kg00qf 3732 27 evidence evidence NN cord-022526-j9kg00qf 3732 28 of of IN cord-022526-j9kg00qf 3732 29 an an DT cord-022526-j9kg00qf 3732 30 enterotoxigenic enterotoxigenic JJ cord-022526-j9kg00qf 3732 31 infection infection NN cord-022526-j9kg00qf 3732 32 than than IN cord-022526-j9kg00qf 3732 33 culture culture NN cord-022526-j9kg00qf 3732 34 alone alone RB cord-022526-j9kg00qf 3732 35 . . . cord-022526-j9kg00qf 3733 1 Immunoassays Immunoassays NNP cord-022526-j9kg00qf 3733 2 are be VBP cord-022526-j9kg00qf 3733 3 available available JJ cord-022526-j9kg00qf 3733 4 that that WDT cord-022526-j9kg00qf 3733 5 are be VBP cord-022526-j9kg00qf 3733 6 primarily primarily RB cord-022526-j9kg00qf 3733 7 designed design VBN cord-022526-j9kg00qf 3733 8 to to TO cord-022526-j9kg00qf 3733 9 detect detect VB cord-022526-j9kg00qf 3733 10 C. C. NNP cord-022526-j9kg00qf 3733 11 perfringens perfringens NN cord-022526-j9kg00qf 3733 12 enterotoxin enterotoxin NN cord-022526-j9kg00qf 3733 13 . . . cord-022526-j9kg00qf 3734 1 83 83 CD cord-022526-j9kg00qf 3735 1 However however RB cord-022526-j9kg00qf 3735 2 , , , cord-022526-j9kg00qf 3735 3 the the DT cord-022526-j9kg00qf 3735 4 reliability reliability NN cord-022526-j9kg00qf 3735 5 ( ( -LRB- cord-022526-j9kg00qf 3735 6 specificity specificity NN cord-022526-j9kg00qf 3735 7 ) ) -RRB- cord-022526-j9kg00qf 3735 8 of of IN cord-022526-j9kg00qf 3735 9 some some DT cord-022526-j9kg00qf 3735 10 immunoassays immunoassay NNS cord-022526-j9kg00qf 3735 11 for for IN cord-022526-j9kg00qf 3735 12 diagnosis diagnosis NN cord-022526-j9kg00qf 3735 13 of of IN cord-022526-j9kg00qf 3735 14 C. C. NNP cord-022526-j9kg00qf 3735 15 perfringens perfringens NN cord-022526-j9kg00qf 3735 16 infection infection NN cord-022526-j9kg00qf 3735 17 has have VBZ cord-022526-j9kg00qf 3735 18 come come VBN cord-022526-j9kg00qf 3735 19 into into IN cord-022526-j9kg00qf 3735 20 question question NN cord-022526-j9kg00qf 3735 21 . . . cord-022526-j9kg00qf 3736 1 Recently recently RB cord-022526-j9kg00qf 3736 2 , , , cord-022526-j9kg00qf 3736 3 PCR PCR NNP cord-022526-j9kg00qf 3736 4 multiplex multiplex NN cord-022526-j9kg00qf 3736 5 and and CC cord-022526-j9kg00qf 3736 6 gene gene NN cord-022526-j9kg00qf 3736 7 probe probe NN cord-022526-j9kg00qf 3736 8 assays assay NNS cord-022526-j9kg00qf 3736 9 have have VBP cord-022526-j9kg00qf 3736 10 been be VBN cord-022526-j9kg00qf 3736 11 developed develop VBN cord-022526-j9kg00qf 3736 12 to to TO cord-022526-j9kg00qf 3736 13 detect detect VB cord-022526-j9kg00qf 3736 14 the the DT cord-022526-j9kg00qf 3736 15 major major JJ cord-022526-j9kg00qf 3736 16 lethal lethal JJ cord-022526-j9kg00qf 3736 17 toxins toxin NNS cord-022526-j9kg00qf 3736 18 in in IN cord-022526-j9kg00qf 3736 19 isolates isolate NNS cord-022526-j9kg00qf 3736 20 or or CC cord-022526-j9kg00qf 3736 21 fecal fecal JJ cord-022526-j9kg00qf 3736 22 samples sample NNS cord-022526-j9kg00qf 3736 23 to to TO cord-022526-j9kg00qf 3736 24 determine determine VB cord-022526-j9kg00qf 3736 25 the the DT cord-022526-j9kg00qf 3736 26 pattern pattern NN cord-022526-j9kg00qf 3736 27 or or CC cord-022526-j9kg00qf 3736 28 toxin toxin NN cord-022526-j9kg00qf 3736 29 production production NN cord-022526-j9kg00qf 3736 30 and and CC cord-022526-j9kg00qf 3736 31 are be VBP cord-022526-j9kg00qf 3736 32 currently currently RB cord-022526-j9kg00qf 3736 33 the the DT cord-022526-j9kg00qf 3736 34 preferred preferred JJ cord-022526-j9kg00qf 3736 35 methods method NNS cord-022526-j9kg00qf 3736 36 of of IN cord-022526-j9kg00qf 3736 37 detection detection NN cord-022526-j9kg00qf 3736 38 . . . cord-022526-j9kg00qf 3737 1 [ [ -LRB- cord-022526-j9kg00qf 3737 2 106 106 CD cord-022526-j9kg00qf 3737 3 ] ] -RRB- cord-022526-j9kg00qf 3737 4 [ [ -LRB- cord-022526-j9kg00qf 3737 5 107 107 CD cord-022526-j9kg00qf 3737 6 ] ] -RRB- cord-022526-j9kg00qf 3738 1 [ [ -LRB- cord-022526-j9kg00qf 3738 2 108 108 CD cord-022526-j9kg00qf 3738 3 ] ] -RRB- cord-022526-j9kg00qf 3739 1 As as IN cord-022526-j9kg00qf 3739 2 for for IN cord-022526-j9kg00qf 3739 3 C. C. NNP cord-022526-j9kg00qf 3739 4 perfringens perfringen NNS cord-022526-j9kg00qf 3739 5 , , , cord-022526-j9kg00qf 3739 6 diagnosis diagnosis NN cord-022526-j9kg00qf 3739 7 of of IN cord-022526-j9kg00qf 3739 8 C. C. NNP cord-022526-j9kg00qf 3739 9 difficile difficile NN cord-022526-j9kg00qf 3739 10 infection infection NN cord-022526-j9kg00qf 3739 11 consists consist VBZ cord-022526-j9kg00qf 3739 12 of of IN cord-022526-j9kg00qf 3739 13 culture culture NN cord-022526-j9kg00qf 3739 14 of of IN cord-022526-j9kg00qf 3739 15 the the DT cord-022526-j9kg00qf 3739 16 organism organism NN cord-022526-j9kg00qf 3739 17 from from IN cord-022526-j9kg00qf 3739 18 feces fece NNS cord-022526-j9kg00qf 3739 19 and and CC cord-022526-j9kg00qf 3739 20 identification identification NN cord-022526-j9kg00qf 3739 21 of of IN cord-022526-j9kg00qf 3739 22 toxins toxin NNS cord-022526-j9kg00qf 3739 23 in in IN cord-022526-j9kg00qf 3739 24 the the DT cord-022526-j9kg00qf 3739 25 feces fece NNS cord-022526-j9kg00qf 3739 26 . . . cord-022526-j9kg00qf 3740 1 Bacterial bacterial JJ cord-022526-j9kg00qf 3740 2 culture culture NN cord-022526-j9kg00qf 3740 3 of of IN cord-022526-j9kg00qf 3740 4 C. C. NNP cord-022526-j9kg00qf 3740 5 difficile difficile NN cord-022526-j9kg00qf 3740 6 may may MD cord-022526-j9kg00qf 3740 7 be be VB cord-022526-j9kg00qf 3740 8 difficult difficult JJ cord-022526-j9kg00qf 3740 9 and and CC cord-022526-j9kg00qf 3740 10 may may MD cord-022526-j9kg00qf 3740 11 be be VB cord-022526-j9kg00qf 3740 12 an an DT cord-022526-j9kg00qf 3740 13 insensitive insensitive JJ cord-022526-j9kg00qf 3740 14 test test NN cord-022526-j9kg00qf 3740 15 in in IN cord-022526-j9kg00qf 3740 16 horses horse NNS cord-022526-j9kg00qf 3740 17 . . . cord-022526-j9kg00qf 3741 1 [ [ -LRB- cord-022526-j9kg00qf 3741 2 109 109 CD cord-022526-j9kg00qf 3741 3 ] ] -RRB- cord-022526-j9kg00qf 3741 4 [ [ -LRB- cord-022526-j9kg00qf 3741 5 110 110 CD cord-022526-j9kg00qf 3741 6 ] ] -RRB- cord-022526-j9kg00qf 3741 7 Detection Detection NNP cord-022526-j9kg00qf 3741 8 may may MD cord-022526-j9kg00qf 3741 9 require require VB cord-022526-j9kg00qf 3741 10 enrichment enrichment NN cord-022526-j9kg00qf 3741 11 techniques technique NNS cord-022526-j9kg00qf 3741 12 and and CC cord-022526-j9kg00qf 3741 13 culture culture NN cord-022526-j9kg00qf 3741 14 of of IN cord-022526-j9kg00qf 3741 15 multiple multiple JJ cord-022526-j9kg00qf 3741 16 fecal fecal JJ cord-022526-j9kg00qf 3741 17 samples sample NNS cord-022526-j9kg00qf 3741 18 . . . cord-022526-j9kg00qf 3742 1 110 110 CD cord-022526-j9kg00qf 3742 2 , , , cord-022526-j9kg00qf 3742 3 111 111 CD cord-022526-j9kg00qf 3742 4 Detection detection NN cord-022526-j9kg00qf 3742 5 of of IN cord-022526-j9kg00qf 3742 6 toxins toxin NNS cord-022526-j9kg00qf 3742 7 A a NN cord-022526-j9kg00qf 3742 8 and and CC cord-022526-j9kg00qf 3742 9 B b NN cord-022526-j9kg00qf 3742 10 in in IN cord-022526-j9kg00qf 3742 11 feces fece NNS cord-022526-j9kg00qf 3742 12 is be VBZ cord-022526-j9kg00qf 3742 13 regarded regard VBN cord-022526-j9kg00qf 3742 14 as as IN cord-022526-j9kg00qf 3742 15 the the DT cord-022526-j9kg00qf 3742 16 preferred preferred JJ cord-022526-j9kg00qf 3742 17 test test NN cord-022526-j9kg00qf 3742 18 for for IN cord-022526-j9kg00qf 3742 19 diagnosis diagnosis NN cord-022526-j9kg00qf 3742 20 of of IN cord-022526-j9kg00qf 3742 21 C. C. NNP cord-022526-j9kg00qf 3742 22 difficile difficile NN cord-022526-j9kg00qf 3742 23 infection infection NN cord-022526-j9kg00qf 3742 24 in in IN cord-022526-j9kg00qf 3742 25 human human JJ cord-022526-j9kg00qf 3742 26 beings being NNS cord-022526-j9kg00qf 3742 27 . . . cord-022526-j9kg00qf 3743 1 83 83 CD cord-022526-j9kg00qf 3743 2 Commercial commercial JJ cord-022526-j9kg00qf 3743 3 enzyme enzyme NN cord-022526-j9kg00qf 3743 4 - - HYPH cord-022526-j9kg00qf 3743 5 linked link VBN cord-022526-j9kg00qf 3743 6 immunosorbent immunosorbent JJ cord-022526-j9kg00qf 3743 7 assays assay NNS cord-022526-j9kg00qf 3743 8 are be VBP cord-022526-j9kg00qf 3743 9 available available JJ cord-022526-j9kg00qf 3743 10 for for IN cord-022526-j9kg00qf 3743 11 toxins toxin NNS cord-022526-j9kg00qf 3743 12 A a NN cord-022526-j9kg00qf 3743 13 and and CC cord-022526-j9kg00qf 3743 14 B b NN cord-022526-j9kg00qf 3743 15 that that WDT cord-022526-j9kg00qf 3743 16 are be VBP cord-022526-j9kg00qf 3743 17 specific specific JJ cord-022526-j9kg00qf 3743 18 and and CC cord-022526-j9kg00qf 3743 19 appear appear VBP cord-022526-j9kg00qf 3743 20 to to TO cord-022526-j9kg00qf 3743 21 be be VB cord-022526-j9kg00qf 3743 22 more more RBR cord-022526-j9kg00qf 3743 23 sensitive sensitive JJ cord-022526-j9kg00qf 3743 24 than than IN cord-022526-j9kg00qf 3743 25 a a DT cord-022526-j9kg00qf 3743 26 single single JJ cord-022526-j9kg00qf 3743 27 culture culture NN cord-022526-j9kg00qf 3743 28 for for IN cord-022526-j9kg00qf 3743 29 identifying identify VBG cord-022526-j9kg00qf 3743 30 C. C. NNP cord-022526-j9kg00qf 3743 31 difficile difficile NN cord-022526-j9kg00qf 3743 32 infection infection NN cord-022526-j9kg00qf 3743 33 in in IN cord-022526-j9kg00qf 3743 34 adult adult NN cord-022526-j9kg00qf 3743 35 horses horse NNS cord-022526-j9kg00qf 3743 36 . . . cord-022526-j9kg00qf 3744 1 109 109 CD cord-022526-j9kg00qf 3744 2 , , , cord-022526-j9kg00qf 3744 3 110 110 CD cord-022526-j9kg00qf 3744 4 One one CD cord-022526-j9kg00qf 3744 5 also also RB cord-022526-j9kg00qf 3744 6 may may MD cord-022526-j9kg00qf 3744 7 induce induce VB cord-022526-j9kg00qf 3744 8 toxin toxin NN cord-022526-j9kg00qf 3744 9 production production NN cord-022526-j9kg00qf 3744 10 by by IN cord-022526-j9kg00qf 3744 11 C. C. NNP cord-022526-j9kg00qf 3744 12 difficile difficile NN cord-022526-j9kg00qf 3744 13 isolates isolate NNS cord-022526-j9kg00qf 3744 14 . . . cord-022526-j9kg00qf 3745 1 Sensitive sensitive JJ cord-022526-j9kg00qf 3745 2 PCR PCR NNP cord-022526-j9kg00qf 3745 3 methods method NNS cord-022526-j9kg00qf 3745 4 also also RB cord-022526-j9kg00qf 3745 5 have have VBP cord-022526-j9kg00qf 3745 6 been be VBN cord-022526-j9kg00qf 3745 7 developed develop VBN cord-022526-j9kg00qf 3745 8 for for IN cord-022526-j9kg00qf 3745 9 application application NN cord-022526-j9kg00qf 3745 10 to to IN cord-022526-j9kg00qf 3745 11 fecal fecal JJ cord-022526-j9kg00qf 3745 12 samples sample NNS cord-022526-j9kg00qf 3745 13 and and CC cord-022526-j9kg00qf 3745 14 isolates isolate NNS cord-022526-j9kg00qf 3745 15 to to TO cord-022526-j9kg00qf 3745 16 detect detect VB cord-022526-j9kg00qf 3745 17 the the DT cord-022526-j9kg00qf 3745 18 genes gene NNS cord-022526-j9kg00qf 3745 19 for for IN cord-022526-j9kg00qf 3746 1 toxins toxin NNS cord-022526-j9kg00qf 3746 2 A A NNP cord-022526-j9kg00qf 3746 3 and and CC cord-022526-j9kg00qf 3746 4 B. B. NNP cord-022526-j9kg00qf 3746 5 83 83 CD cord-022526-j9kg00qf 3746 6 Proliferative Proliferative NNP cord-022526-j9kg00qf 3746 7 enteropathy enteropathy NNP cord-022526-j9kg00qf 3746 8 is be VBZ cord-022526-j9kg00qf 3746 9 a a DT cord-022526-j9kg00qf 3746 10 chronic chronic JJ cord-022526-j9kg00qf 3746 11 hyperplastic hyperplastic JJ cord-022526-j9kg00qf 3746 12 disorder disorder NN cord-022526-j9kg00qf 3746 13 of of IN cord-022526-j9kg00qf 3746 14 the the DT cord-022526-j9kg00qf 3746 15 small small JJ cord-022526-j9kg00qf 3746 16 intestine intestine NN cord-022526-j9kg00qf 3746 17 and and CC cord-022526-j9kg00qf 3746 18 has have VBZ cord-022526-j9kg00qf 3746 19 been be VBN cord-022526-j9kg00qf 3746 20 described describe VBN cord-022526-j9kg00qf 3746 21 in in IN cord-022526-j9kg00qf 3746 22 a a DT cord-022526-j9kg00qf 3746 23 variety variety NN cord-022526-j9kg00qf 3746 24 of of IN cord-022526-j9kg00qf 3746 25 mammalian mammalian JJ cord-022526-j9kg00qf 3746 26 and and CC cord-022526-j9kg00qf 3746 27 avian avian JJ cord-022526-j9kg00qf 3746 28 species specie NNS cord-022526-j9kg00qf 3746 29 . . . cord-022526-j9kg00qf 3747 1 112 112 CD cord-022526-j9kg00qf 3747 2 , , , cord-022526-j9kg00qf 3747 3 113 113 CD cord-022526-j9kg00qf 3748 1 The the DT cord-022526-j9kg00qf 3748 2 only only JJ cord-022526-j9kg00qf 3748 3 causative causative JJ cord-022526-j9kg00qf 3748 4 agent agent NN cord-022526-j9kg00qf 3748 5 identified identify VBN cord-022526-j9kg00qf 3748 6 to to IN cord-022526-j9kg00qf 3748 7 date date NN cord-022526-j9kg00qf 3748 8 that that WDT cord-022526-j9kg00qf 3748 9 induces induce VBZ cord-022526-j9kg00qf 3748 10 proliferative proliferative JJ cord-022526-j9kg00qf 3748 11 enteropathy enteropathy NNP cord-022526-j9kg00qf 3748 12 is be VBZ cord-022526-j9kg00qf 3748 13 the the DT cord-022526-j9kg00qf 3748 14 obligate obligate JJ cord-022526-j9kg00qf 3748 15 intracellular intracellular JJ cord-022526-j9kg00qf 3748 16 pathogen pathogen NN cord-022526-j9kg00qf 3748 17 Lawsonia Lawsonia NNP cord-022526-j9kg00qf 3748 18 intracellulare intracellulare NNP cord-022526-j9kg00qf 3748 19 . . . cord-022526-j9kg00qf 3749 1 113 113 CD cord-022526-j9kg00qf 3749 2 , , , cord-022526-j9kg00qf 3749 3 114 114 CD cord-022526-j9kg00qf 3750 1 The the DT cord-022526-j9kg00qf 3750 2 pig pig NN cord-022526-j9kg00qf 3750 3 is be VBZ cord-022526-j9kg00qf 3750 4 the the DT cord-022526-j9kg00qf 3750 5 most most RBS cord-022526-j9kg00qf 3750 6 frequently frequently RB cord-022526-j9kg00qf 3750 7 naturally naturally RB cord-022526-j9kg00qf 3750 8 affected affect VBN cord-022526-j9kg00qf 3750 9 species specie NNS cord-022526-j9kg00qf 3750 10 . . . cord-022526-j9kg00qf 3751 1 However however RB cord-022526-j9kg00qf 3751 2 , , , cord-022526-j9kg00qf 3751 3 the the DT cord-022526-j9kg00qf 3751 4 reports report NNS cord-022526-j9kg00qf 3751 5 of of IN cord-022526-j9kg00qf 3751 6 equine equine JJ cord-022526-j9kg00qf 3751 7 proliferative proliferative JJ cord-022526-j9kg00qf 3751 8 enteropathy enteropathy NN cord-022526-j9kg00qf 3751 9 associated associate VBN cord-022526-j9kg00qf 3751 10 with with IN cord-022526-j9kg00qf 3751 11 L. L. NNP cord-022526-j9kg00qf 3751 12 intracellulare intracellulare NNP cord-022526-j9kg00qf 3751 13 have have VBP cord-022526-j9kg00qf 3751 14 increased increase VBN cord-022526-j9kg00qf 3751 15 in in IN cord-022526-j9kg00qf 3751 16 recent recent JJ cord-022526-j9kg00qf 3751 17 years year NNS cord-022526-j9kg00qf 3751 18 . . . cord-022526-j9kg00qf 3752 1 [ [ -LRB- cord-022526-j9kg00qf 3752 2 115 115 CD cord-022526-j9kg00qf 3752 3 ] ] -RRB- cord-022526-j9kg00qf 3752 4 [ [ -LRB- cord-022526-j9kg00qf 3752 5 116 116 CD cord-022526-j9kg00qf 3752 6 ] ] -RRB- cord-022526-j9kg00qf 3752 7 [ [ -LRB- cord-022526-j9kg00qf 3752 8 117 117 CD cord-022526-j9kg00qf 3752 9 ] ] -RRB- cord-022526-j9kg00qf 3752 10 [ [ -LRB- cord-022526-j9kg00qf 3752 11 118 118 CD cord-022526-j9kg00qf 3752 12 ] ] -RRB- cord-022526-j9kg00qf 3753 1 The the DT cord-022526-j9kg00qf 3753 2 relatedness relatedness NN cord-022526-j9kg00qf 3753 3 of of IN cord-022526-j9kg00qf 3753 4 the the DT cord-022526-j9kg00qf 3753 5 strains strain NNS cord-022526-j9kg00qf 3753 6 of of IN cord-022526-j9kg00qf 3753 7 L. L. NNP cord-022526-j9kg00qf 3753 8 intracellulare intracellulare NNP cord-022526-j9kg00qf 3753 9 causing cause VBG cord-022526-j9kg00qf 3753 10 proliferative proliferative JJ cord-022526-j9kg00qf 3753 11 enteropathy enteropathy NN cord-022526-j9kg00qf 3753 12 in in IN cord-022526-j9kg00qf 3753 13 pigs pig NNS cord-022526-j9kg00qf 3753 14 and and CC cord-022526-j9kg00qf 3753 15 horses horse NNS cord-022526-j9kg00qf 3753 16 or or CC cord-022526-j9kg00qf 3753 17 even even RB cord-022526-j9kg00qf 3753 18 among among IN cord-022526-j9kg00qf 3753 19 other other JJ cord-022526-j9kg00qf 3753 20 affected affect VBN cord-022526-j9kg00qf 3753 21 species specie NNS cord-022526-j9kg00qf 3753 22 is be VBZ cord-022526-j9kg00qf 3753 23 not not RB cord-022526-j9kg00qf 3753 24 known know VBN cord-022526-j9kg00qf 3753 25 . . . cord-022526-j9kg00qf 3754 1 No no DT cord-022526-j9kg00qf 3754 2 host host NN cord-022526-j9kg00qf 3754 3 restriction restriction NN cord-022526-j9kg00qf 3754 4 is be VBZ cord-022526-j9kg00qf 3754 5 apparent apparent JJ cord-022526-j9kg00qf 3754 6 because because IN cord-022526-j9kg00qf 3754 7 hamsters hamster NNS cord-022526-j9kg00qf 3754 8 and and CC cord-022526-j9kg00qf 3754 9 other other JJ cord-022526-j9kg00qf 3754 10 rodents rodent NNS cord-022526-j9kg00qf 3754 11 can can MD cord-022526-j9kg00qf 3754 12 be be VB cord-022526-j9kg00qf 3754 13 infected infect VBN cord-022526-j9kg00qf 3754 14 with with IN cord-022526-j9kg00qf 3754 15 porcine porcine JJ cord-022526-j9kg00qf 3754 16 strains strain NNS cord-022526-j9kg00qf 3754 17 of of IN cord-022526-j9kg00qf 3754 18 L. L. NNP cord-022526-j9kg00qf 3754 19 intracellulare intracellulare NNP cord-022526-j9kg00qf 3754 20 . . . cord-022526-j9kg00qf 3755 1 Before before IN cord-022526-j9kg00qf 3755 2 the the DT cord-022526-j9kg00qf 3755 3 year year NN cord-022526-j9kg00qf 3755 4 2000 2000 CD cord-022526-j9kg00qf 3755 5 , , , cord-022526-j9kg00qf 3755 6 reports report NNS cord-022526-j9kg00qf 3755 7 of of IN cord-022526-j9kg00qf 3755 8 proliferative proliferative JJ cord-022526-j9kg00qf 3755 9 enteropathy enteropathy NNS cord-022526-j9kg00qf 3755 10 in in IN cord-022526-j9kg00qf 3755 11 the the DT cord-022526-j9kg00qf 3755 12 literature literature NN cord-022526-j9kg00qf 3755 13 describing describe VBG cord-022526-j9kg00qf 3755 14 isolated isolate VBN cord-022526-j9kg00qf 3755 15 cases case NNS cord-022526-j9kg00qf 3755 16 were be VBD cord-022526-j9kg00qf 3755 17 sporadic sporadic JJ cord-022526-j9kg00qf 3755 18 . . . cord-022526-j9kg00qf 3756 1 [ [ -LRB- cord-022526-j9kg00qf 3756 2 116 116 CD cord-022526-j9kg00qf 3756 3 ] ] -RRB- cord-022526-j9kg00qf 3756 4 [ [ -LRB- cord-022526-j9kg00qf 3756 5 117 117 CD cord-022526-j9kg00qf 3756 6 ] ] -RRB- cord-022526-j9kg00qf 3757 1 [ [ -LRB- cord-022526-j9kg00qf 3757 2 118 118 CD cord-022526-j9kg00qf 3757 3 ] ] -RRB- cord-022526-j9kg00qf 3758 1 However however RB cord-022526-j9kg00qf 3758 2 , , , cord-022526-j9kg00qf 3758 3 since since IN cord-022526-j9kg00qf 3758 4 2000 2000 CD cord-022526-j9kg00qf 3758 5 , , , cord-022526-j9kg00qf 3758 6 outbreaks outbreak NNS cord-022526-j9kg00qf 3758 7 on on IN cord-022526-j9kg00qf 3758 8 breeding breed VBG cord-022526-j9kg00qf 3758 9 farms farm NNS cord-022526-j9kg00qf 3758 10 have have VBP cord-022526-j9kg00qf 3758 11 been be VBN cord-022526-j9kg00qf 3758 12 documented document VBN cord-022526-j9kg00qf 3758 13 on on IN cord-022526-j9kg00qf 3758 14 farms farm NNS cord-022526-j9kg00qf 3758 15 in in IN cord-022526-j9kg00qf 3758 16 Canada Canada NNP cord-022526-j9kg00qf 3758 17 , , , cord-022526-j9kg00qf 3758 18 suggesting suggest VBG cord-022526-j9kg00qf 3758 19 that that IN cord-022526-j9kg00qf 3758 20 a a DT cord-022526-j9kg00qf 3758 21 new new JJ cord-022526-j9kg00qf 3758 22 strain strain NN cord-022526-j9kg00qf 3758 23 has have VBZ cord-022526-j9kg00qf 3758 24 emerged emerge VBN cord-022526-j9kg00qf 3758 25 . . . cord-022526-j9kg00qf 3759 1 115 115 CD cord-022526-j9kg00qf 3760 1 The the DT cord-022526-j9kg00qf 3760 2 mode mode NN cord-022526-j9kg00qf 3760 3 of of IN cord-022526-j9kg00qf 3760 4 infection infection NN cord-022526-j9kg00qf 3760 5 is be VBZ cord-022526-j9kg00qf 3760 6 fecal fecal JJ cord-022526-j9kg00qf 3760 7 - - HYPH cord-022526-j9kg00qf 3760 8 oral oral JJ cord-022526-j9kg00qf 3760 9 , , , cord-022526-j9kg00qf 3760 10 and and CC cord-022526-j9kg00qf 3760 11 infected infected JJ cord-022526-j9kg00qf 3760 12 animals animal NNS cord-022526-j9kg00qf 3760 13 can can MD cord-022526-j9kg00qf 3760 14 shed shed VB cord-022526-j9kg00qf 3760 15 large large JJ cord-022526-j9kg00qf 3760 16 numbers number NNS cord-022526-j9kg00qf 3760 17 of of IN cord-022526-j9kg00qf 3760 18 organisms organism NNS cord-022526-j9kg00qf 3760 19 in in IN cord-022526-j9kg00qf 3760 20 feces fece NNS cord-022526-j9kg00qf 3760 21 . . . cord-022526-j9kg00qf 3761 1 113 113 CD cord-022526-j9kg00qf 3761 2 Affected affect VBN cord-022526-j9kg00qf 3761 3 animals animal NNS cord-022526-j9kg00qf 3761 4 shedding shed VBG cord-022526-j9kg00qf 3761 5 the the DT cord-022526-j9kg00qf 3761 6 organism organism NN cord-022526-j9kg00qf 3761 7 in in IN cord-022526-j9kg00qf 3761 8 the the DT cord-022526-j9kg00qf 3761 9 feces fece NNS cord-022526-j9kg00qf 3761 10 serve serve VBP cord-022526-j9kg00qf 3761 11 as as IN cord-022526-j9kg00qf 3761 12 a a DT cord-022526-j9kg00qf 3761 13 source source NN cord-022526-j9kg00qf 3761 14 of of IN cord-022526-j9kg00qf 3761 15 infection infection NN cord-022526-j9kg00qf 3761 16 for for IN cord-022526-j9kg00qf 3761 17 herdmates herdmate NNS cord-022526-j9kg00qf 3761 18 . . . cord-022526-j9kg00qf 3762 1 Possibly possibly RB cord-022526-j9kg00qf 3762 2 nonequine nonequine NNP cord-022526-j9kg00qf 3762 3 species specie NNS cord-022526-j9kg00qf 3762 4 serve serve VBP cord-022526-j9kg00qf 3762 5 as as IN cord-022526-j9kg00qf 3762 6 reservoirs reservoir NNS cord-022526-j9kg00qf 3762 7 contributing contribute VBG cord-022526-j9kg00qf 3762 8 to to IN cord-022526-j9kg00qf 3762 9 outbreaks outbreak NNS cord-022526-j9kg00qf 3762 10 on on IN cord-022526-j9kg00qf 3762 11 horse horse NN cord-022526-j9kg00qf 3762 12 farms farm NNS cord-022526-j9kg00qf 3762 13 . . . cord-022526-j9kg00qf 3763 1 Factors factor NNS cord-022526-j9kg00qf 3763 2 that that WDT cord-022526-j9kg00qf 3763 3 increase increase VBP cord-022526-j9kg00qf 3763 4 the the DT cord-022526-j9kg00qf 3763 5 risk risk NN cord-022526-j9kg00qf 3763 6 of of IN cord-022526-j9kg00qf 3763 7 proliferative proliferative JJ cord-022526-j9kg00qf 3763 8 enteropathy enteropathy NNS cord-022526-j9kg00qf 3763 9 in in IN cord-022526-j9kg00qf 3763 10 pigs pig NNS cord-022526-j9kg00qf 3763 11 include include VBP cord-022526-j9kg00qf 3763 12 overcrowding overcrowding NN cord-022526-j9kg00qf 3763 13 , , , cord-022526-j9kg00qf 3763 14 ration ration NN cord-022526-j9kg00qf 3763 15 changes change NNS cord-022526-j9kg00qf 3763 16 , , , cord-022526-j9kg00qf 3763 17 transport transport NN cord-022526-j9kg00qf 3763 18 , , , cord-022526-j9kg00qf 3763 19 and and CC cord-022526-j9kg00qf 3763 20 weaning weaning NN cord-022526-j9kg00qf 3763 21 . . . cord-022526-j9kg00qf 3764 1 113 113 CD cord-022526-j9kg00qf 3764 2 , , , cord-022526-j9kg00qf 3764 3 114 114 CD cord-022526-j9kg00qf 3765 1 Like like IN cord-022526-j9kg00qf 3765 2 pigs pig NNS cord-022526-j9kg00qf 3765 3 , , , cord-022526-j9kg00qf 3765 4 horses horse NNS cord-022526-j9kg00qf 3765 5 are be VBP cord-022526-j9kg00qf 3765 6 affected affect VBN cord-022526-j9kg00qf 3765 7 as as IN cord-022526-j9kg00qf 3765 8 weanlings weanling NNS cord-022526-j9kg00qf 3765 9 . . . cord-022526-j9kg00qf 3766 1 Factors factor NNS cord-022526-j9kg00qf 3766 2 associated associate VBN cord-022526-j9kg00qf 3766 3 with with IN cord-022526-j9kg00qf 3766 4 weaning weaning NN cord-022526-j9kg00qf 3766 5 and and CC cord-022526-j9kg00qf 3766 6 other other JJ cord-022526-j9kg00qf 3766 7 stresses stress NNS cord-022526-j9kg00qf 3766 8 may may MD cord-022526-j9kg00qf 3766 9 affect affect VB cord-022526-j9kg00qf 3766 10 immunity immunity NN cord-022526-j9kg00qf 3766 11 and and CC cord-022526-j9kg00qf 3766 12 increase increase VB cord-022526-j9kg00qf 3766 13 susceptibility susceptibility NN cord-022526-j9kg00qf 3766 14 to to IN cord-022526-j9kg00qf 3766 15 infection infection NN cord-022526-j9kg00qf 3766 16 . . . cord-022526-j9kg00qf 3767 1 The the DT cord-022526-j9kg00qf 3767 2 incubation incubation NN cord-022526-j9kg00qf 3767 3 period period NN cord-022526-j9kg00qf 3767 4 is be VBZ cord-022526-j9kg00qf 3767 5 2 2 CD cord-022526-j9kg00qf 3767 6 to to TO cord-022526-j9kg00qf 3767 7 3 3 CD cord-022526-j9kg00qf 3767 8 weeks week NNS cord-022526-j9kg00qf 3767 9 in in IN cord-022526-j9kg00qf 3767 10 nonequine nonequine NNP cord-022526-j9kg00qf 3767 11 species specie NNS cord-022526-j9kg00qf 3767 12 and and CC cord-022526-j9kg00qf 3767 13 is be VBZ cord-022526-j9kg00qf 3767 14 presumed presume VBN cord-022526-j9kg00qf 3767 15 to to TO cord-022526-j9kg00qf 3767 16 be be VB cord-022526-j9kg00qf 3767 17 similar similar JJ cord-022526-j9kg00qf 3767 18 in in IN cord-022526-j9kg00qf 3767 19 horses horse NNS cord-022526-j9kg00qf 3767 20 . . . cord-022526-j9kg00qf 3768 1 Experimental Experimental NNP cord-022526-j9kg00qf 3768 2 L. L. NNP cord-022526-j9kg00qf 3768 3 intracellulare intracellulare NNP cord-022526-j9kg00qf 3768 4 infection infection NN cord-022526-j9kg00qf 3768 5 produces produce VBZ cord-022526-j9kg00qf 3768 6 characteristic characteristic JJ cord-022526-j9kg00qf 3768 7 pathologic pathologic JJ cord-022526-j9kg00qf 3768 8 lesions lesion NNS cord-022526-j9kg00qf 3768 9 in in IN cord-022526-j9kg00qf 3768 10 pigs pig NNS cord-022526-j9kg00qf 3768 11 and and CC cord-022526-j9kg00qf 3768 12 hamsters hamster NNS cord-022526-j9kg00qf 3768 13 that that WDT cord-022526-j9kg00qf 3768 14 are be VBP cord-022526-j9kg00qf 3768 15 identical identical JJ cord-022526-j9kg00qf 3768 16 to to IN cord-022526-j9kg00qf 3768 17 lesions lesion NNS cord-022526-j9kg00qf 3768 18 in in IN cord-022526-j9kg00qf 3768 19 horses horse NNS cord-022526-j9kg00qf 3768 20 with with IN cord-022526-j9kg00qf 3768 21 proliferative proliferative JJ cord-022526-j9kg00qf 3768 22 enteropathy enteropathy NNS cord-022526-j9kg00qf 3768 23 . . . cord-022526-j9kg00qf 3769 1 113 113 CD cord-022526-j9kg00qf 3769 2 , , , cord-022526-j9kg00qf 3769 3 114 114 CD cord-022526-j9kg00qf 3770 1 A a DT cord-022526-j9kg00qf 3770 2 profound profound JJ cord-022526-j9kg00qf 3770 3 hyperplasia hyperplasia NN cord-022526-j9kg00qf 3770 4 of of IN cord-022526-j9kg00qf 3770 5 the the DT cord-022526-j9kg00qf 3770 6 mucosa mucosa NN cord-022526-j9kg00qf 3770 7 predominantly predominantly RB cord-022526-j9kg00qf 3770 8 caused cause VBN cord-022526-j9kg00qf 3770 9 by by IN cord-022526-j9kg00qf 3770 10 proliferation proliferation NN cord-022526-j9kg00qf 3770 11 of of IN cord-022526-j9kg00qf 3770 12 crypt crypt JJ cord-022526-j9kg00qf 3770 13 epithelium epithelium NN cord-022526-j9kg00qf 3770 14 and and CC cord-022526-j9kg00qf 3770 15 crypt crypt NN cord-022526-j9kg00qf 3771 1 hyperplasia hyperplasia NN cord-022526-j9kg00qf 3771 2 is be VBZ cord-022526-j9kg00qf 3771 3 induced induce VBN cord-022526-j9kg00qf 3771 4 locally locally RB cord-022526-j9kg00qf 3771 5 in in IN cord-022526-j9kg00qf 3771 6 infected infected JJ cord-022526-j9kg00qf 3771 7 islands island NNS cord-022526-j9kg00qf 3771 8 of of IN cord-022526-j9kg00qf 3771 9 tissue tissue NN cord-022526-j9kg00qf 3771 10 and and CC cord-022526-j9kg00qf 3771 11 eventually eventually RB cord-022526-j9kg00qf 3771 12 extends extend VBZ cord-022526-j9kg00qf 3771 13 to to IN cord-022526-j9kg00qf 3771 14 the the DT cord-022526-j9kg00qf 3771 15 entire entire JJ cord-022526-j9kg00qf 3771 16 distal distal JJ cord-022526-j9kg00qf 3771 17 jejunum jejunum NNS cord-022526-j9kg00qf 3771 18 and and CC cord-022526-j9kg00qf 3771 19 ileum ileum NN cord-022526-j9kg00qf 3771 20 . . . cord-022526-j9kg00qf 3772 1 L. L. NNP cord-022526-j9kg00qf 3772 2 intracellulare intracellulare NNP cord-022526-j9kg00qf 3772 3 preferentially preferentially RB cord-022526-j9kg00qf 3772 4 infects infect VBZ cord-022526-j9kg00qf 3772 5 proliferating proliferate VBG cord-022526-j9kg00qf 3772 6 cells cell NNS cord-022526-j9kg00qf 3772 7 , , , cord-022526-j9kg00qf 3773 1 thus thus RB cord-022526-j9kg00qf 3773 2 the the DT cord-022526-j9kg00qf 3773 3 tropism tropism NN cord-022526-j9kg00qf 3773 4 for for IN cord-022526-j9kg00qf 3773 5 the the DT cord-022526-j9kg00qf 3773 6 crypt crypt JJ cord-022526-j9kg00qf 3773 7 epithelium epithelium NN cord-022526-j9kg00qf 3773 8 . . . cord-022526-j9kg00qf 3774 1 Infected infected JJ cord-022526-j9kg00qf 3774 2 cells cell NNS cord-022526-j9kg00qf 3774 3 proliferate proliferate VBP cord-022526-j9kg00qf 3774 4 far far RB cord-022526-j9kg00qf 3774 5 more more RBR cord-022526-j9kg00qf 3774 6 rapidly rapidly RB cord-022526-j9kg00qf 3774 7 than than IN cord-022526-j9kg00qf 3774 8 uninfected uninfected JJ cord-022526-j9kg00qf 3774 9 cells cell NNS cord-022526-j9kg00qf 3774 10 , , , cord-022526-j9kg00qf 3774 11 suggesting suggest VBG cord-022526-j9kg00qf 3774 12 that that IN cord-022526-j9kg00qf 3774 13 L. L. NNP cord-022526-j9kg00qf 3774 14 intracellulare intracellulare NNP cord-022526-j9kg00qf 3774 15 directly directly RB cord-022526-j9kg00qf 3774 16 induced induce VBD cord-022526-j9kg00qf 3774 17 the the DT cord-022526-j9kg00qf 3774 18 proliferative proliferative JJ cord-022526-j9kg00qf 3774 19 response response NN cord-022526-j9kg00qf 3774 20 . . . cord-022526-j9kg00qf 3775 1 However however RB cord-022526-j9kg00qf 3775 2 , , , cord-022526-j9kg00qf 3775 3 the the DT cord-022526-j9kg00qf 3775 4 molecular molecular JJ cord-022526-j9kg00qf 3775 5 basis basis NN cord-022526-j9kg00qf 3775 6 for for IN cord-022526-j9kg00qf 3775 7 the the DT cord-022526-j9kg00qf 3775 8 enhanced enhance VBN cord-022526-j9kg00qf 3775 9 proliferation proliferation NN cord-022526-j9kg00qf 3775 10 is be VBZ cord-022526-j9kg00qf 3775 11 not not RB cord-022526-j9kg00qf 3775 12 known know VBN cord-022526-j9kg00qf 3775 13 . . . cord-022526-j9kg00qf 3776 1 L. L. NNP cord-022526-j9kg00qf 3776 2 intracellulare intracellulare NNP cord-022526-j9kg00qf 3776 3 penetrates penetrate VBZ cord-022526-j9kg00qf 3776 4 epithelial epithelial JJ cord-022526-j9kg00qf 3776 5 cells cell NNS cord-022526-j9kg00qf 3776 6 in in IN cord-022526-j9kg00qf 3776 7 a a DT cord-022526-j9kg00qf 3776 8 membrane membrane NN cord-022526-j9kg00qf 3776 9 - - HYPH cord-022526-j9kg00qf 3776 10 bound bind VBN cord-022526-j9kg00qf 3776 11 vesicle vesicle NN cord-022526-j9kg00qf 3776 12 but but CC cord-022526-j9kg00qf 3776 13 eventually eventually RB cord-022526-j9kg00qf 3776 14 escapes escape VBZ cord-022526-j9kg00qf 3776 15 the the DT cord-022526-j9kg00qf 3776 16 vacuole vacuole NN cord-022526-j9kg00qf 3776 17 and and CC cord-022526-j9kg00qf 3776 18 is be VBZ cord-022526-j9kg00qf 3776 19 found find VBN cord-022526-j9kg00qf 3776 20 free free JJ cord-022526-j9kg00qf 3776 21 in in IN cord-022526-j9kg00qf 3776 22 the the DT cord-022526-j9kg00qf 3776 23 cytoplasm cytoplasm NN cord-022526-j9kg00qf 3776 24 concentrated concentrate VBN cord-022526-j9kg00qf 3776 25 at at IN cord-022526-j9kg00qf 3776 26 the the DT cord-022526-j9kg00qf 3776 27 apical apical JJ cord-022526-j9kg00qf 3776 28 pole pole NN cord-022526-j9kg00qf 3776 29 of of IN cord-022526-j9kg00qf 3776 30 the the DT cord-022526-j9kg00qf 3776 31 cell cell NN cord-022526-j9kg00qf 3776 32 . . . cord-022526-j9kg00qf 3777 1 The the DT cord-022526-j9kg00qf 3777 2 gross gross JJ cord-022526-j9kg00qf 3777 3 pathologic pathologic JJ cord-022526-j9kg00qf 3777 4 lesions lesion NNS cord-022526-j9kg00qf 3777 5 found find VBN cord-022526-j9kg00qf 3777 6 in in IN cord-022526-j9kg00qf 3777 7 equine equine JJ cord-022526-j9kg00qf 3777 8 proliferative proliferative JJ cord-022526-j9kg00qf 3777 9 enteropathy enteropathy NNS cord-022526-j9kg00qf 3777 10 are be VBP cord-022526-j9kg00qf 3777 11 characteristic characteristic JJ cord-022526-j9kg00qf 3777 12 . . . cord-022526-j9kg00qf 3778 1 [ [ -LRB- cord-022526-j9kg00qf 3778 2 115 115 CD cord-022526-j9kg00qf 3778 3 ] ] -RRB- cord-022526-j9kg00qf 3778 4 [ [ -LRB- cord-022526-j9kg00qf 3778 5 116 116 CD cord-022526-j9kg00qf 3778 6 ] ] -RRB- cord-022526-j9kg00qf 3778 7 [ [ -LRB- cord-022526-j9kg00qf 3778 8 117 117 CD cord-022526-j9kg00qf 3778 9 ] ] -RRB- cord-022526-j9kg00qf 3778 10 [ [ -LRB- cord-022526-j9kg00qf 3778 11 118 118 CD cord-022526-j9kg00qf 3778 12 ] ] -RRB- cord-022526-j9kg00qf 3779 1 Lesions lesion NNS cord-022526-j9kg00qf 3779 2 may may MD cord-022526-j9kg00qf 3779 3 be be VB cord-022526-j9kg00qf 3779 4 segmental segmental JJ cord-022526-j9kg00qf 3779 5 and and CC cord-022526-j9kg00qf 3779 6 typically typically RB cord-022526-j9kg00qf 3779 7 are be VBP cord-022526-j9kg00qf 3779 8 found find VBN cord-022526-j9kg00qf 3779 9 in in IN cord-022526-j9kg00qf 3779 10 the the DT cord-022526-j9kg00qf 3779 11 ileum ileum NN cord-022526-j9kg00qf 3779 12 and and CC cord-022526-j9kg00qf 3779 13 terminal terminal JJ cord-022526-j9kg00qf 3779 14 jejunum jejunum NNS cord-022526-j9kg00qf 3779 15 in in IN cord-022526-j9kg00qf 3779 16 horses horse NNS cord-022526-j9kg00qf 3779 17 . . . cord-022526-j9kg00qf 3780 1 However however RB cord-022526-j9kg00qf 3780 2 , , , cord-022526-j9kg00qf 3780 3 lesions lesion NNS cord-022526-j9kg00qf 3780 4 also also RB cord-022526-j9kg00qf 3780 5 may may MD cord-022526-j9kg00qf 3780 6 affect affect VB cord-022526-j9kg00qf 3780 7 the the DT cord-022526-j9kg00qf 3780 8 duodenum duodenum NN cord-022526-j9kg00qf 3780 9 . . . cord-022526-j9kg00qf 3781 1 Severe severe JJ cord-022526-j9kg00qf 3781 2 mucosal mucosal JJ cord-022526-j9kg00qf 3781 3 hypertrophy hypertrophy NN cord-022526-j9kg00qf 3781 4 often often RB cord-022526-j9kg00qf 3781 5 occurs occur VBZ cord-022526-j9kg00qf 3781 6 but but CC cord-022526-j9kg00qf 3781 7 may may MD cord-022526-j9kg00qf 3781 8 wane wane VB cord-022526-j9kg00qf 3781 9 during during IN cord-022526-j9kg00qf 3781 10 the the DT cord-022526-j9kg00qf 3781 11 chronic chronic JJ cord-022526-j9kg00qf 3781 12 stages stage NNS cord-022526-j9kg00qf 3781 13 of of IN cord-022526-j9kg00qf 3781 14 the the DT cord-022526-j9kg00qf 3781 15 disease disease NN cord-022526-j9kg00qf 3781 16 . . . cord-022526-j9kg00qf 3782 1 The the DT cord-022526-j9kg00qf 3782 2 mucosa mucosa NN cord-022526-j9kg00qf 3782 3 may may MD cord-022526-j9kg00qf 3782 4 become become VB cord-022526-j9kg00qf 3782 5 corrugated corrugated JJ cord-022526-j9kg00qf 3782 6 with with IN cord-022526-j9kg00qf 3782 7 focal focal JJ cord-022526-j9kg00qf 3782 8 erosions erosion NNS cord-022526-j9kg00qf 3782 9 or or CC cord-022526-j9kg00qf 3782 10 ulcers ulcer NNS cord-022526-j9kg00qf 3782 11 . . . cord-022526-j9kg00qf 3783 1 One one CD cord-022526-j9kg00qf 3783 2 often often RB cord-022526-j9kg00qf 3783 3 can can MD cord-022526-j9kg00qf 3783 4 identify identify VB cord-022526-j9kg00qf 3783 5 submucosal submucosal NN cord-022526-j9kg00qf 3783 6 edema edema NN cord-022526-j9kg00qf 3783 7 easily easily RB cord-022526-j9kg00qf 3783 8 on on IN cord-022526-j9kg00qf 3783 9 cut cut NN cord-022526-j9kg00qf 3783 10 sections section NNS cord-022526-j9kg00qf 3783 11 of of IN cord-022526-j9kg00qf 3783 12 affected affect VBN cord-022526-j9kg00qf 3783 13 segments segment NNS cord-022526-j9kg00qf 3783 14 . . . cord-022526-j9kg00qf 3784 1 Moderate moderate JJ cord-022526-j9kg00qf 3784 2 to to IN cord-022526-j9kg00qf 3784 3 severe severe JJ cord-022526-j9kg00qf 3784 4 crypt crypt JJ cord-022526-j9kg00qf 3784 5 hyperplasia hyperplasia NN cord-022526-j9kg00qf 3784 6 with with IN cord-022526-j9kg00qf 3784 7 atrophy atrophy NN cord-022526-j9kg00qf 3784 8 of of IN cord-022526-j9kg00qf 3784 9 the the DT cord-022526-j9kg00qf 3784 10 intestinal intestinal JJ cord-022526-j9kg00qf 3784 11 villi villi NN cord-022526-j9kg00qf 3784 12 is be VBZ cord-022526-j9kg00qf 3784 13 a a DT cord-022526-j9kg00qf 3784 14 consistent consistent JJ cord-022526-j9kg00qf 3784 15 feature feature NN cord-022526-j9kg00qf 3784 16 . . . cord-022526-j9kg00qf 3785 1 The the DT cord-022526-j9kg00qf 3785 2 hyperplastic hyperplastic JJ cord-022526-j9kg00qf 3785 3 crypts crypt NNS cord-022526-j9kg00qf 3785 4 are be VBP cord-022526-j9kg00qf 3785 5 branched branch VBN cord-022526-j9kg00qf 3785 6 and and CC cord-022526-j9kg00qf 3785 7 may may MD cord-022526-j9kg00qf 3785 8 herniate herniate VB cord-022526-j9kg00qf 3785 9 into into IN cord-022526-j9kg00qf 3785 10 the the DT cord-022526-j9kg00qf 3785 11 submucosa submucosa NN cord-022526-j9kg00qf 3785 12 . . . cord-022526-j9kg00qf 3786 1 Necrosis necrosis NN cord-022526-j9kg00qf 3786 2 , , , cord-022526-j9kg00qf 3786 3 edema edema NN cord-022526-j9kg00qf 3786 4 of of IN cord-022526-j9kg00qf 3786 5 the the DT cord-022526-j9kg00qf 3786 6 submucosal submucosal NN cord-022526-j9kg00qf 3786 7 and and CC cord-022526-j9kg00qf 3786 8 lamina lamina NNP cord-022526-j9kg00qf 3786 9 propria propria NN cord-022526-j9kg00qf 3786 10 , , , cord-022526-j9kg00qf 3786 11 hemorrhage hemorrhage NN cord-022526-j9kg00qf 3786 12 , , , cord-022526-j9kg00qf 3786 13 mononuclear mononuclear JJ cord-022526-j9kg00qf 3786 14 inflammation inflammation NN cord-022526-j9kg00qf 3786 15 and and CC cord-022526-j9kg00qf 3786 16 muscular muscular JJ cord-022526-j9kg00qf 3786 17 hypertrophy hypertrophy NN cord-022526-j9kg00qf 3786 18 have have VBP cord-022526-j9kg00qf 3786 19 been be VBN cord-022526-j9kg00qf 3786 20 reported report VBN cord-022526-j9kg00qf 3786 21 in in IN cord-022526-j9kg00qf 3786 22 affected affected JJ cord-022526-j9kg00qf 3786 23 intestinal intestinal JJ cord-022526-j9kg00qf 3786 24 segments segment NNS cord-022526-j9kg00qf 3786 25 but but CC cord-022526-j9kg00qf 3786 26 are be VBP cord-022526-j9kg00qf 3786 27 not not RB cord-022526-j9kg00qf 3786 28 consistent consistent JJ cord-022526-j9kg00qf 3786 29 . . . cord-022526-j9kg00qf 3787 1 Special special JJ cord-022526-j9kg00qf 3787 2 stains stain NNS cord-022526-j9kg00qf 3787 3 such such JJ cord-022526-j9kg00qf 3787 4 as as IN cord-022526-j9kg00qf 3787 5 silver silver NN cord-022526-j9kg00qf 3787 6 stain stain NN cord-022526-j9kg00qf 3787 7 are be VBP cord-022526-j9kg00qf 3787 8 required require VBN cord-022526-j9kg00qf 3787 9 to to TO cord-022526-j9kg00qf 3787 10 detect detect VB cord-022526-j9kg00qf 3787 11 intracellular intracellular JJ cord-022526-j9kg00qf 3787 12 organisms organism NNS cord-022526-j9kg00qf 3787 13 . . . cord-022526-j9kg00qf 3788 1 The the DT cord-022526-j9kg00qf 3788 2 organisms organism NNS cord-022526-j9kg00qf 3788 3 are be VBP cord-022526-j9kg00qf 3788 4 curved curved JJ cord-022526-j9kg00qf 3788 5 or or CC cord-022526-j9kg00qf 3788 6 comma comma JJ cord-022526-j9kg00qf 3788 7 - - HYPH cord-022526-j9kg00qf 3788 8 shaped shape VBN cord-022526-j9kg00qf 3788 9 rods rod NNS cord-022526-j9kg00qf 3788 10 found find VBN cord-022526-j9kg00qf 3788 11 clustered cluster VBN cord-022526-j9kg00qf 3788 12 in in IN cord-022526-j9kg00qf 3788 13 the the DT cord-022526-j9kg00qf 3788 14 apical apical JJ cord-022526-j9kg00qf 3788 15 cytoplasm cytoplasm NN cord-022526-j9kg00qf 3788 16 of of IN cord-022526-j9kg00qf 3788 17 hyperplastic hyperplastic JJ cord-022526-j9kg00qf 3788 18 crypt crypt NN cord-022526-j9kg00qf 3788 19 epithelium epithelium NN cord-022526-j9kg00qf 3788 20 . . . cord-022526-j9kg00qf 3789 1 The the DT cord-022526-j9kg00qf 3789 2 proliferative proliferative JJ cord-022526-j9kg00qf 3789 3 response response NN cord-022526-j9kg00qf 3789 4 of of IN cord-022526-j9kg00qf 3789 5 the the DT cord-022526-j9kg00qf 3789 6 intestinal intestinal JJ cord-022526-j9kg00qf 3789 7 mucosa mucosa NN cord-022526-j9kg00qf 3789 8 alters alter VBZ cord-022526-j9kg00qf 3789 9 absorption absorption NN cord-022526-j9kg00qf 3789 10 of of IN cord-022526-j9kg00qf 3789 11 nutrients nutrient NNS cord-022526-j9kg00qf 3789 12 and and CC cord-022526-j9kg00qf 3789 13 fluid fluid JJ cord-022526-j9kg00qf 3789 14 secretion secretion NN cord-022526-j9kg00qf 3789 15 by by IN cord-022526-j9kg00qf 3789 16 disrupting disrupt VBG cord-022526-j9kg00qf 3789 17 the the DT cord-022526-j9kg00qf 3789 18 architecture architecture NN cord-022526-j9kg00qf 3789 19 of of IN cord-022526-j9kg00qf 3789 20 the the DT cord-022526-j9kg00qf 3789 21 villi villi NN cord-022526-j9kg00qf 3789 22 and and CC cord-022526-j9kg00qf 3789 23 by by IN cord-022526-j9kg00qf 3789 24 altering alter VBG cord-022526-j9kg00qf 3789 25 the the DT cord-022526-j9kg00qf 3789 26 maturation maturation NN cord-022526-j9kg00qf 3789 27 of of IN cord-022526-j9kg00qf 3789 28 epithelial epithelial JJ cord-022526-j9kg00qf 3789 29 cells cell NNS cord-022526-j9kg00qf 3789 30 into into IN cord-022526-j9kg00qf 3789 31 absorptive absorptive JJ cord-022526-j9kg00qf 3789 32 cells cell NNS cord-022526-j9kg00qf 3789 33 , , , cord-022526-j9kg00qf 3789 34 accounting account VBG cord-022526-j9kg00qf 3789 35 for for IN cord-022526-j9kg00qf 3789 36 the the DT cord-022526-j9kg00qf 3789 37 secretory secretory JJ cord-022526-j9kg00qf 3789 38 diarrhea diarrhea NN cord-022526-j9kg00qf 3789 39 and and CC cord-022526-j9kg00qf 3789 40 often often RB cord-022526-j9kg00qf 3789 41 severe severe JJ cord-022526-j9kg00qf 3789 42 weight weight NN cord-022526-j9kg00qf 3789 43 loss loss NN cord-022526-j9kg00qf 3789 44 . . . cord-022526-j9kg00qf 3790 1 112 112 CD cord-022526-j9kg00qf 3790 2 , , , cord-022526-j9kg00qf 3790 3 114 114 CD cord-022526-j9kg00qf 3791 1 The the DT cord-022526-j9kg00qf 3791 2 combined combined JJ cord-022526-j9kg00qf 3791 3 effects effect NNS cord-022526-j9kg00qf 3791 4 of of IN cord-022526-j9kg00qf 3791 5 the the DT cord-022526-j9kg00qf 3791 6 inflammatory inflammatory JJ cord-022526-j9kg00qf 3791 7 892 892 CD cord-022526-j9kg00qf 3791 8 PART part NN cord-022526-j9kg00qf 3791 9 II ii CD cord-022526-j9kg00qf 3791 10 Disorders disorder NNS cord-022526-j9kg00qf 3791 11 of of IN cord-022526-j9kg00qf 3791 12 Specific specific JJ cord-022526-j9kg00qf 3791 13 Body Body NNP cord-022526-j9kg00qf 3791 14 Systems Systems NNPS cord-022526-j9kg00qf 3791 15 response response NN cord-022526-j9kg00qf 3791 16 and and CC cord-022526-j9kg00qf 3791 17 malabsorption malabsorption NN cord-022526-j9kg00qf 3791 18 may may MD cord-022526-j9kg00qf 3791 19 account account VB cord-022526-j9kg00qf 3791 20 for for IN cord-022526-j9kg00qf 3791 21 the the DT cord-022526-j9kg00qf 3791 22 protein protein NN cord-022526-j9kg00qf 3791 23 - - HYPH cord-022526-j9kg00qf 3791 24 losing lose VBG cord-022526-j9kg00qf 3791 25 enteropathy enteropathy NNP cord-022526-j9kg00qf 3791 26 . . . cord-022526-j9kg00qf 3792 1 Proliferative Proliferative NNP cord-022526-j9kg00qf 3792 2 enteritis enteritis NN cord-022526-j9kg00qf 3792 3 most most RBS cord-022526-j9kg00qf 3792 4 commonly commonly RB cord-022526-j9kg00qf 3792 5 affects affect VBZ cord-022526-j9kg00qf 3792 6 weanling weanle VBG cord-022526-j9kg00qf 3792 7 foals foal NNS cord-022526-j9kg00qf 3792 8 ages age NNS cord-022526-j9kg00qf 3792 9 4 4 CD cord-022526-j9kg00qf 3792 10 to to TO cord-022526-j9kg00qf 3792 11 6 6 CD cord-022526-j9kg00qf 3792 12 months month NNS cord-022526-j9kg00qf 3792 13 . . . cord-022526-j9kg00qf 3793 1 The the DT cord-022526-j9kg00qf 3793 2 clinical clinical JJ cord-022526-j9kg00qf 3793 3 signs sign NNS cord-022526-j9kg00qf 3793 4 of of IN cord-022526-j9kg00qf 3793 5 proliferative proliferative JJ cord-022526-j9kg00qf 3793 6 enteropathy enteropathy NNS cord-022526-j9kg00qf 3793 7 include include VBP cord-022526-j9kg00qf 3793 8 ill ill JJ cord-022526-j9kg00qf 3793 9 thrift thrift NN cord-022526-j9kg00qf 3793 10 , , , cord-022526-j9kg00qf 3793 11 weight weight NN cord-022526-j9kg00qf 3793 12 loss loss NN cord-022526-j9kg00qf 3793 13 , , , cord-022526-j9kg00qf 3793 14 peripheral peripheral JJ cord-022526-j9kg00qf 3793 15 edema edema NN cord-022526-j9kg00qf 3793 16 , , , cord-022526-j9kg00qf 3793 17 diarrhea diarrhea NN cord-022526-j9kg00qf 3793 18 , , , cord-022526-j9kg00qf 3793 19 and and CC cord-022526-j9kg00qf 3793 20 colic colic NN cord-022526-j9kg00qf 3793 21 . . . cord-022526-j9kg00qf 3794 1 [ [ -LRB- cord-022526-j9kg00qf 3794 2 115 115 CD cord-022526-j9kg00qf 3794 3 ] ] -RRB- cord-022526-j9kg00qf 3794 4 [ [ -LRB- cord-022526-j9kg00qf 3794 5 116 116 CD cord-022526-j9kg00qf 3794 6 ] ] -RRB- cord-022526-j9kg00qf 3794 7 [ [ -LRB- cord-022526-j9kg00qf 3794 8 117 117 CD cord-022526-j9kg00qf 3794 9 ] ] -RRB- cord-022526-j9kg00qf 3795 1 [ [ -LRB- cord-022526-j9kg00qf 3795 2 118 118 CD cord-022526-j9kg00qf 3795 3 ] ] -RRB- cord-022526-j9kg00qf 3796 1 The the DT cord-022526-j9kg00qf 3796 2 diarrhea diarrhea NN cord-022526-j9kg00qf 3796 3 is be VBZ cord-022526-j9kg00qf 3796 4 usually usually RB cord-022526-j9kg00qf 3796 5 in in IN cord-022526-j9kg00qf 3796 6 the the DT cord-022526-j9kg00qf 3796 7 form form NN cord-022526-j9kg00qf 3796 8 of of IN cord-022526-j9kg00qf 3796 9 soft soft JJ cord-022526-j9kg00qf 3796 10 feces fece NNS cord-022526-j9kg00qf 3796 11 but but CC cord-022526-j9kg00qf 3796 12 may may MD cord-022526-j9kg00qf 3796 13 be be VB cord-022526-j9kg00qf 3796 14 profuse profuse JJ cord-022526-j9kg00qf 3796 15 and and CC cord-022526-j9kg00qf 3796 16 watery watery JJ cord-022526-j9kg00qf 3796 17 . . . cord-022526-j9kg00qf 3797 1 Some some DT cord-022526-j9kg00qf 3797 2 foals foal NNS cord-022526-j9kg00qf 3797 3 with with IN cord-022526-j9kg00qf 3797 4 mild mild JJ cord-022526-j9kg00qf 3797 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3797 6 have have VBP cord-022526-j9kg00qf 3797 7 black black JJ cord-022526-j9kg00qf 3797 8 , , , cord-022526-j9kg00qf 3797 9 tarry tarry VB cord-022526-j9kg00qf 3797 10 feces fece NNS cord-022526-j9kg00qf 3797 11 . . . cord-022526-j9kg00qf 3798 1 Secondary secondary JJ cord-022526-j9kg00qf 3798 2 complications complication NNS cord-022526-j9kg00qf 3798 3 such such JJ cord-022526-j9kg00qf 3798 4 as as IN cord-022526-j9kg00qf 3798 5 gastric gastric JJ cord-022526-j9kg00qf 3798 6 ulceration ulceration NN cord-022526-j9kg00qf 3798 7 , , , cord-022526-j9kg00qf 3798 8 bronchopneumonia bronchopneumonia NN cord-022526-j9kg00qf 3798 9 , , , cord-022526-j9kg00qf 3798 10 or or CC cord-022526-j9kg00qf 3798 11 parasitism parasitism NN cord-022526-j9kg00qf 3798 12 may may MD cord-022526-j9kg00qf 3798 13 occur occur VB cord-022526-j9kg00qf 3798 14 concurrently concurrently RB cord-022526-j9kg00qf 3798 15 with with IN cord-022526-j9kg00qf 3798 16 the the DT cord-022526-j9kg00qf 3798 17 proliferative proliferative JJ cord-022526-j9kg00qf 3798 18 enteropathy enteropathy NNP cord-022526-j9kg00qf 3798 19 . . . cord-022526-j9kg00qf 3799 1 Clinicopathologic Clinicopathologic NNP cord-022526-j9kg00qf 3799 2 features feature NNS cord-022526-j9kg00qf 3799 3 include include VBP cord-022526-j9kg00qf 3799 4 mild mild JJ cord-022526-j9kg00qf 3799 5 to to IN cord-022526-j9kg00qf 3799 6 moderate moderate JJ cord-022526-j9kg00qf 3799 7 anemia anemia NN cord-022526-j9kg00qf 3799 8 , , , cord-022526-j9kg00qf 3799 9 moderate moderate JJ cord-022526-j9kg00qf 3799 10 to to IN cord-022526-j9kg00qf 3799 11 severe severe JJ cord-022526-j9kg00qf 3799 12 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3799 13 ( ( -LRB- cord-022526-j9kg00qf 3799 14 often often RB cord-022526-j9kg00qf 3799 15 < < XX cord-022526-j9kg00qf 3799 16 2 2 CD cord-022526-j9kg00qf 3799 17 g g NN cord-022526-j9kg00qf 3799 18 / / SYM cord-022526-j9kg00qf 3799 19 dl dl NNP cord-022526-j9kg00qf 3799 20 ) ) -RRB- cord-022526-j9kg00qf 3799 21 , , , cord-022526-j9kg00qf 3799 22 hypoglobulinemia hypoglobulinemia NNP cord-022526-j9kg00qf 3799 23 , , , cord-022526-j9kg00qf 3799 24 neutrophilic neutrophilic NNP cord-022526-j9kg00qf 3799 25 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 3799 26 , , , cord-022526-j9kg00qf 3799 27 and and CC cord-022526-j9kg00qf 3799 28 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 3799 29 . . . cord-022526-j9kg00qf 3800 1 Creatine creatine NN cord-022526-j9kg00qf 3800 2 kinase kinase NN cord-022526-j9kg00qf 3800 3 activities activity NNS cord-022526-j9kg00qf 3800 4 may may MD cord-022526-j9kg00qf 3800 5 be be VB cord-022526-j9kg00qf 3800 6 elevated elevate VBN cord-022526-j9kg00qf 3800 7 in in IN cord-022526-j9kg00qf 3800 8 affected affect VBN cord-022526-j9kg00qf 3800 9 foals foal NNS cord-022526-j9kg00qf 3800 10 . . . cord-022526-j9kg00qf 3801 1 Prerenal Prerenal NNP cord-022526-j9kg00qf 3801 2 azotemia azotemia NN cord-022526-j9kg00qf 3801 3 and and CC cord-022526-j9kg00qf 3801 4 electrolyte electrolyte NN cord-022526-j9kg00qf 3801 5 imbalances imbalance NNS cord-022526-j9kg00qf 3801 6 such such JJ cord-022526-j9kg00qf 3801 7 as as IN cord-022526-j9kg00qf 3801 8 hyponatremia hyponatremia NN cord-022526-j9kg00qf 3801 9 may may MD cord-022526-j9kg00qf 3801 10 be be VB cord-022526-j9kg00qf 3801 11 associated associate VBN cord-022526-j9kg00qf 3801 12 with with IN cord-022526-j9kg00qf 3801 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3801 14 . . . cord-022526-j9kg00qf 3802 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 3802 2 fluid fluid JJ cord-022526-j9kg00qf 3802 3 analysis analysis NN cord-022526-j9kg00qf 3802 4 is be VBZ cord-022526-j9kg00qf 3802 5 usually usually RB cord-022526-j9kg00qf 3802 6 unremarkable unremarkable JJ cord-022526-j9kg00qf 3802 7 . . . cord-022526-j9kg00qf 3803 1 Ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 3803 2 examination examination NN cord-022526-j9kg00qf 3803 3 of of IN cord-022526-j9kg00qf 3803 4 the the DT cord-022526-j9kg00qf 3803 5 small small JJ cord-022526-j9kg00qf 3803 6 intestine intestine NN cord-022526-j9kg00qf 3803 7 often often RB cord-022526-j9kg00qf 3803 8 reveals reveal VBZ cord-022526-j9kg00qf 3803 9 significant significant JJ cord-022526-j9kg00qf 3803 10 thickening thickening NN cord-022526-j9kg00qf 3803 11 of of IN cord-022526-j9kg00qf 3803 12 the the DT cord-022526-j9kg00qf 3803 13 intestinal intestinal JJ cord-022526-j9kg00qf 3803 14 wall wall NN cord-022526-j9kg00qf 3803 15 ( ( -LRB- cord-022526-j9kg00qf 3803 16 Figure figure NN cord-022526-j9kg00qf 3803 17 13 13 CD cord-022526-j9kg00qf 3803 18 .13 .13 CD cord-022526-j9kg00qf 3803 19 - - SYM cord-022526-j9kg00qf 3803 20 1 1 CD cord-022526-j9kg00qf 3803 21 ) ) -RRB- cord-022526-j9kg00qf 3803 22 . . . cord-022526-j9kg00qf 3804 1 Intestinal intestinal JJ cord-022526-j9kg00qf 3804 2 edema edema NN cord-022526-j9kg00qf 3804 3 may may MD cord-022526-j9kg00qf 3804 4 be be VB cord-022526-j9kg00qf 3804 5 evident evident JJ cord-022526-j9kg00qf 3804 6 as as IN cord-022526-j9kg00qf 3804 7 a a DT cord-022526-j9kg00qf 3804 8 hypoechoic hypoechoic JJ cord-022526-j9kg00qf 3804 9 appearance appearance NN cord-022526-j9kg00qf 3804 10 to to IN cord-022526-j9kg00qf 3804 11 one one CD cord-022526-j9kg00qf 3804 12 or or CC cord-022526-j9kg00qf 3804 13 more more JJR cord-022526-j9kg00qf 3804 14 layers layer NNS cord-022526-j9kg00qf 3804 15 of of IN cord-022526-j9kg00qf 3804 16 the the DT cord-022526-j9kg00qf 3804 17 intestinal intestinal JJ cord-022526-j9kg00qf 3804 18 wall wall NN cord-022526-j9kg00qf 3804 19 . . . cord-022526-j9kg00qf 3805 1 Methods method NNS cord-022526-j9kg00qf 3805 2 for for IN cord-022526-j9kg00qf 3805 3 antemortem antemortem NNP cord-022526-j9kg00qf 3805 4 diagnosis diagnosis NN cord-022526-j9kg00qf 3805 5 include include VBP cord-022526-j9kg00qf 3805 6 serologic serologic NNP cord-022526-j9kg00qf 3805 7 analysis analysis NN cord-022526-j9kg00qf 3805 8 of of IN cord-022526-j9kg00qf 3805 9 L. L. NNP cord-022526-j9kg00qf 3805 10 intracellulare intracellulare NNP cord-022526-j9kg00qf 3805 11 antibodies antibody NNS cord-022526-j9kg00qf 3805 12 and and CC cord-022526-j9kg00qf 3805 13 PCR PCR NNP cord-022526-j9kg00qf 3805 14 analysis analysis NN cord-022526-j9kg00qf 3805 15 of of IN cord-022526-j9kg00qf 3805 16 feces fece NNS cord-022526-j9kg00qf 3805 17 . . . cord-022526-j9kg00qf 3806 1 115 115 CD cord-022526-j9kg00qf 3806 2 Serologic Serologic NNP cord-022526-j9kg00qf 3806 3 analysis analysis NN cord-022526-j9kg00qf 3806 4 using use VBG cord-022526-j9kg00qf 3806 5 an an DT cord-022526-j9kg00qf 3806 6 indirect indirect JJ cord-022526-j9kg00qf 3806 7 immunofluorescent immunofluorescent JJ cord-022526-j9kg00qf 3806 8 antibody antibody NN cord-022526-j9kg00qf 3806 9 test test NN cord-022526-j9kg00qf 3806 10 may may MD cord-022526-j9kg00qf 3806 11 be be VB cord-022526-j9kg00qf 3806 12 the the DT cord-022526-j9kg00qf 3806 13 most most RBS cord-022526-j9kg00qf 3806 14 useful useful JJ cord-022526-j9kg00qf 3806 15 single single JJ cord-022526-j9kg00qf 3806 16 test test NN cord-022526-j9kg00qf 3806 17 available available JJ cord-022526-j9kg00qf 3806 18 . . . cord-022526-j9kg00qf 3807 1 The the DT cord-022526-j9kg00qf 3807 2 PCR PCR NNP cord-022526-j9kg00qf 3807 3 test test NN cord-022526-j9kg00qf 3807 4 is be VBZ cord-022526-j9kg00qf 3807 5 specific specific JJ cord-022526-j9kg00qf 3807 6 but but CC cord-022526-j9kg00qf 3807 7 the the DT cord-022526-j9kg00qf 3807 8 sensitivity sensitivity NN cord-022526-j9kg00qf 3807 9 may may MD cord-022526-j9kg00qf 3807 10 be be VB cord-022526-j9kg00qf 3807 11 low low JJ cord-022526-j9kg00qf 3807 12 . . . cord-022526-j9kg00qf 3808 1 By by IN cord-022526-j9kg00qf 3808 2 the the DT cord-022526-j9kg00qf 3808 3 time time NN cord-022526-j9kg00qf 3808 4 clinical clinical JJ cord-022526-j9kg00qf 3808 5 signs sign NNS cord-022526-j9kg00qf 3808 6 appear appear VBP cord-022526-j9kg00qf 3808 7 , , , cord-022526-j9kg00qf 3808 8 90 90 CD cord-022526-j9kg00qf 3808 9 % % NN cord-022526-j9kg00qf 3808 10 of of IN cord-022526-j9kg00qf 3808 11 pigs pig NNS cord-022526-j9kg00qf 3808 12 are be VBP cord-022526-j9kg00qf 3808 13 serologically serologically RB cord-022526-j9kg00qf 3808 14 positive positive JJ cord-022526-j9kg00qf 3808 15 for for IN cord-022526-j9kg00qf 3808 16 anti anti JJ cord-022526-j9kg00qf 3808 17 - - JJ cord-022526-j9kg00qf 3808 18 Lawsonia Lawsonia NNP cord-022526-j9kg00qf 3808 19 intracellulare intracellulare NN cord-022526-j9kg00qf 3808 20 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 3808 21 G g NN cord-022526-j9kg00qf 3808 22 ( ( -LRB- cord-022526-j9kg00qf 3808 23 IgG IgG NNP cord-022526-j9kg00qf 3808 24 ) ) -RRB- cord-022526-j9kg00qf 3808 25 . . . cord-022526-j9kg00qf 3809 1 In in IN cord-022526-j9kg00qf 3809 2 contrast contrast NN cord-022526-j9kg00qf 3809 3 , , , cord-022526-j9kg00qf 3809 4 only only RB cord-022526-j9kg00qf 3809 5 37 37 CD cord-022526-j9kg00qf 3809 6 % % NN cord-022526-j9kg00qf 3809 7 of of IN cord-022526-j9kg00qf 3809 8 pigs pig NNS cord-022526-j9kg00qf 3809 9 had have VBD cord-022526-j9kg00qf 3809 10 positive positive JJ cord-022526-j9kg00qf 3809 11 fecal fecal JJ cord-022526-j9kg00qf 3809 12 PCR PCR NNP cord-022526-j9kg00qf 3809 13 tests test NNS cord-022526-j9kg00qf 3809 14 . . . cord-022526-j9kg00qf 3810 1 119 119 CD cord-022526-j9kg00qf 3810 2 Of of IN cord-022526-j9kg00qf 3810 3 the the DT cord-022526-j9kg00qf 3810 4 seven seven CD cord-022526-j9kg00qf 3810 5 foals foal NNS cord-022526-j9kg00qf 3810 6 tested test VBN cord-022526-j9kg00qf 3810 7 in in IN cord-022526-j9kg00qf 3810 8 an an DT cord-022526-j9kg00qf 3810 9 outbreak outbreak NN cord-022526-j9kg00qf 3810 10 of of IN cord-022526-j9kg00qf 3810 11 equine equine JJ cord-022526-j9kg00qf 3810 12 proliferative proliferative JJ cord-022526-j9kg00qf 3810 13 enteropathy enteropathy NNP cord-022526-j9kg00qf 3810 14 , , , cord-022526-j9kg00qf 3810 15 115 115 CD cord-022526-j9kg00qf 3810 16 four four CD cord-022526-j9kg00qf 3810 17 foals foal NNS cord-022526-j9kg00qf 3810 18 with with IN cord-022526-j9kg00qf 3810 19 confirmed confirm VBN cord-022526-j9kg00qf 3810 20 disease disease NN cord-022526-j9kg00qf 3810 21 and and CC cord-022526-j9kg00qf 3810 22 three three CD cord-022526-j9kg00qf 3810 23 with with IN cord-022526-j9kg00qf 3810 24 suspected suspect VBN cord-022526-j9kg00qf 3810 25 proliferative proliferative JJ cord-022526-j9kg00qf 3810 26 enteropathy enteropathy NNS cord-022526-j9kg00qf 3810 27 had have VBD cord-022526-j9kg00qf 3810 28 serologic serologic JJ cord-022526-j9kg00qf 3810 29 titers titer NNS cord-022526-j9kg00qf 3810 30 against against IN cord-022526-j9kg00qf 3810 31 L. L. NNP cord-022526-j9kg00qf 3810 32 intracellulare intracellulare NNP cord-022526-j9kg00qf 3810 33 of of IN cord-022526-j9kg00qf 3810 34 1:30 1:30 CD cord-022526-j9kg00qf 3810 35 or or CC cord-022526-j9kg00qf 3810 36 greater great JJR cord-022526-j9kg00qf 3810 37 . . . cord-022526-j9kg00qf 3811 1 In in IN cord-022526-j9kg00qf 3811 2 contrast contrast NN cord-022526-j9kg00qf 3811 3 , , , cord-022526-j9kg00qf 3811 4 serum serum NN cord-022526-j9kg00qf 3811 5 samples sample NNS cord-022526-j9kg00qf 3811 6 collected collect VBN cord-022526-j9kg00qf 3811 7 from from IN cord-022526-j9kg00qf 3811 8 72 72 CD cord-022526-j9kg00qf 3811 9 foals foal NNS cord-022526-j9kg00qf 3811 10 before before IN cord-022526-j9kg00qf 3811 11 the the DT cord-022526-j9kg00qf 3811 12 outbreak outbreak NN cord-022526-j9kg00qf 3811 13 were be VBD cord-022526-j9kg00qf 3811 14 negative negative JJ cord-022526-j9kg00qf 3811 15 for for IN cord-022526-j9kg00qf 3811 16 L. L. NNP cord-022526-j9kg00qf 3811 17 intracellulare intracellulare NNP cord-022526-j9kg00qf 3811 18 antibodies antibody NNS cord-022526-j9kg00qf 3811 19 . . . cord-022526-j9kg00qf 3812 1 Fecal Fecal NNP cord-022526-j9kg00qf 3812 2 PCR PCR NNP cord-022526-j9kg00qf 3812 3 for for IN cord-022526-j9kg00qf 3812 4 L. L. NNP cord-022526-j9kg00qf 3812 5 intracellulare intracellulare NNP cord-022526-j9kg00qf 3812 6 was be VBD cord-022526-j9kg00qf 3812 7 positive positive JJ cord-022526-j9kg00qf 3812 8 in in IN cord-022526-j9kg00qf 3812 9 6 6 CD cord-022526-j9kg00qf 3812 10 of of IN cord-022526-j9kg00qf 3812 11 18 18 CD cord-022526-j9kg00qf 3812 12 foals foal NNS cord-022526-j9kg00qf 3812 13 tested test VBN cord-022526-j9kg00qf 3812 14 , , , cord-022526-j9kg00qf 3812 15 and and CC cord-022526-j9kg00qf 3812 16 half half NN cord-022526-j9kg00qf 3812 17 of of IN cord-022526-j9kg00qf 3812 18 the the DT cord-022526-j9kg00qf 3812 19 serologically serologically RB cord-022526-j9kg00qf 3812 20 positive positive JJ cord-022526-j9kg00qf 3812 21 foals foal NNS cord-022526-j9kg00qf 3812 22 had have VBD cord-022526-j9kg00qf 3812 23 negative negative JJ cord-022526-j9kg00qf 3812 24 fecal fecal JJ cord-022526-j9kg00qf 3812 25 PCR PCR NNP cord-022526-j9kg00qf 3812 26 tests test NNS cord-022526-j9kg00qf 3812 27 . . . cord-022526-j9kg00qf 3813 1 Many many JJ cord-022526-j9kg00qf 3813 2 clinicians clinician NNS cord-022526-j9kg00qf 3813 3 combine combine VBP cord-022526-j9kg00qf 3813 4 serologic serologic JJ cord-022526-j9kg00qf 3813 5 analysis analysis NN cord-022526-j9kg00qf 3813 6 with with IN cord-022526-j9kg00qf 3813 7 fecal fecal JJ cord-022526-j9kg00qf 3813 8 PCR PCR NNP cord-022526-j9kg00qf 3813 9 testing testing NN cord-022526-j9kg00qf 3813 10 to to TO cord-022526-j9kg00qf 3813 11 increase increase VB cord-022526-j9kg00qf 3813 12 the the DT cord-022526-j9kg00qf 3813 13 sensitivity sensitivity NN cord-022526-j9kg00qf 3813 14 and and CC cord-022526-j9kg00qf 3813 15 specificity specificity NN cord-022526-j9kg00qf 3813 16 of of IN cord-022526-j9kg00qf 3813 17 these these DT cord-022526-j9kg00qf 3813 18 diagnostic diagnostic JJ cord-022526-j9kg00qf 3813 19 methods method NNS cord-022526-j9kg00qf 3813 20 . . . cord-022526-j9kg00qf 3814 1 Isolation isolation NN cord-022526-j9kg00qf 3814 2 and and CC cord-022526-j9kg00qf 3814 3 culture culture NN cord-022526-j9kg00qf 3814 4 of of IN cord-022526-j9kg00qf 3814 5 the the DT cord-022526-j9kg00qf 3814 6 organism organism NN cord-022526-j9kg00qf 3814 7 requires require VBZ cord-022526-j9kg00qf 3814 8 cell cell NN cord-022526-j9kg00qf 3814 9 culture culture NN cord-022526-j9kg00qf 3814 10 techniques technique NNS cord-022526-j9kg00qf 3814 11 that that WDT cord-022526-j9kg00qf 3814 12 are be VBP cord-022526-j9kg00qf 3814 13 not not RB cord-022526-j9kg00qf 3814 14 widely widely RB cord-022526-j9kg00qf 3814 15 available available JJ cord-022526-j9kg00qf 3814 16 . . . cord-022526-j9kg00qf 3815 1 Thus thus RB cord-022526-j9kg00qf 3815 2 no no DT cord-022526-j9kg00qf 3815 3 practical practical JJ cord-022526-j9kg00qf 3815 4 method method NN cord-022526-j9kg00qf 3815 5 exists exist VBZ cord-022526-j9kg00qf 3815 6 for for IN cord-022526-j9kg00qf 3815 7 culturing culture VBG cord-022526-j9kg00qf 3815 8 the the DT cord-022526-j9kg00qf 3815 9 organism organism NN cord-022526-j9kg00qf 3815 10 from from IN cord-022526-j9kg00qf 3815 11 feces fece NNS cord-022526-j9kg00qf 3815 12 or or CC cord-022526-j9kg00qf 3815 13 tissues tissue NNS cord-022526-j9kg00qf 3815 14 that that WDT cord-022526-j9kg00qf 3815 15 is be VBZ cord-022526-j9kg00qf 3815 16 available available JJ cord-022526-j9kg00qf 3815 17 for for IN cord-022526-j9kg00qf 3815 18 clinical clinical JJ cord-022526-j9kg00qf 3815 19 use use NN cord-022526-j9kg00qf 3815 20 . . . cord-022526-j9kg00qf 3816 1 Definitive definitive JJ cord-022526-j9kg00qf 3816 2 diagnosis diagnosis NN cord-022526-j9kg00qf 3816 3 requires require VBZ cord-022526-j9kg00qf 3816 4 histopathologic histopathologic JJ cord-022526-j9kg00qf 3816 5 examination examination NN cord-022526-j9kg00qf 3816 6 of of IN cord-022526-j9kg00qf 3816 7 affected affected JJ cord-022526-j9kg00qf 3816 8 tissues tissue NNS cord-022526-j9kg00qf 3816 9 . . . cord-022526-j9kg00qf 3817 1 112 112 CD cord-022526-j9kg00qf 3817 2 Diagnosis diagnosis NN cord-022526-j9kg00qf 3817 3 is be VBZ cord-022526-j9kg00qf 3817 4 based base VBN cord-022526-j9kg00qf 3817 5 on on IN cord-022526-j9kg00qf 3817 6 typical typical JJ cord-022526-j9kg00qf 3817 7 histopathologic histopathologic JJ cord-022526-j9kg00qf 3817 8 findings finding NNS cord-022526-j9kg00qf 3817 9 of of IN cord-022526-j9kg00qf 3817 10 mucosal mucosal JJ cord-022526-j9kg00qf 3817 11 hypertrophy hypertrophy NN cord-022526-j9kg00qf 3817 12 and and CC cord-022526-j9kg00qf 3817 13 submucosal submucosal NN cord-022526-j9kg00qf 3817 14 edema edema NN cord-022526-j9kg00qf 3817 15 and and CC cord-022526-j9kg00qf 3817 16 identification identification NN cord-022526-j9kg00qf 3817 17 of of IN cord-022526-j9kg00qf 3817 18 small small JJ cord-022526-j9kg00qf 3817 19 , , , cord-022526-j9kg00qf 3817 20 curved curved JJ cord-022526-j9kg00qf 3817 21 , , , cord-022526-j9kg00qf 3817 22 rod rod NN cord-022526-j9kg00qf 3817 23 - - HYPH cord-022526-j9kg00qf 3817 24 shaped shape VBN cord-022526-j9kg00qf 3817 25 intracellular intracellular JJ cord-022526-j9kg00qf 3817 26 bacteria bacteria NNS cord-022526-j9kg00qf 3817 27 at at IN cord-022526-j9kg00qf 3817 28 the the DT cord-022526-j9kg00qf 3817 29 apical apical JJ cord-022526-j9kg00qf 3817 30 pole pole NN cord-022526-j9kg00qf 3817 31 of of IN cord-022526-j9kg00qf 3817 32 epithelial epithelial JJ cord-022526-j9kg00qf 3817 33 cells cell NNS cord-022526-j9kg00qf 3817 34 in in IN cord-022526-j9kg00qf 3817 35 affected affected JJ cord-022526-j9kg00qf 3817 36 segments segment NNS cord-022526-j9kg00qf 3817 37 of of IN cord-022526-j9kg00qf 3817 38 intestine intestine NN cord-022526-j9kg00qf 3817 39 . . . cord-022526-j9kg00qf 3818 1 Special special JJ cord-022526-j9kg00qf 3818 2 stains stain NNS cord-022526-j9kg00qf 3818 3 such such JJ cord-022526-j9kg00qf 3818 4 as as IN cord-022526-j9kg00qf 3818 5 Warthin Warthin NNP cord-022526-j9kg00qf 3818 6 - - HYPH cord-022526-j9kg00qf 3818 7 Starry Starry NNP cord-022526-j9kg00qf 3818 8 silver silver NN cord-022526-j9kg00qf 3818 9 stain stain NN cord-022526-j9kg00qf 3818 10 are be VBP cord-022526-j9kg00qf 3818 11 required require VBN cord-022526-j9kg00qf 3818 12 to to TO cord-022526-j9kg00qf 3818 13 detect detect VB cord-022526-j9kg00qf 3818 14 the the DT cord-022526-j9kg00qf 3818 15 bacteria bacteria NNS cord-022526-j9kg00qf 3818 16 in in IN cord-022526-j9kg00qf 3818 17 histopathologic histopathologic JJ cord-022526-j9kg00qf 3818 18 specimens specimen NNS cord-022526-j9kg00qf 3818 19 . . . cord-022526-j9kg00qf 3819 1 PCR PCR NNP cord-022526-j9kg00qf 3819 2 analysis analysis NN cord-022526-j9kg00qf 3819 3 of of IN cord-022526-j9kg00qf 3819 4 affected affected JJ cord-022526-j9kg00qf 3819 5 intestinal intestinal JJ cord-022526-j9kg00qf 3819 6 tissue tissue NN cord-022526-j9kg00qf 3819 7 is be VBZ cord-022526-j9kg00qf 3819 8 a a DT cord-022526-j9kg00qf 3819 9 specific specific JJ cord-022526-j9kg00qf 3819 10 test test NN cord-022526-j9kg00qf 3819 11 for for IN cord-022526-j9kg00qf 3819 12 the the DT cord-022526-j9kg00qf 3819 13 presence presence NN cord-022526-j9kg00qf 3819 14 of of IN cord-022526-j9kg00qf 3819 15 L. L. NNP cord-022526-j9kg00qf 3819 16 intracellulare intracellulare NNP cord-022526-j9kg00qf 3819 17 and and CC cord-022526-j9kg00qf 3819 18 , , , cord-022526-j9kg00qf 3819 19 unlike unlike IN cord-022526-j9kg00qf 3819 20 fecal fecal JJ cord-022526-j9kg00qf 3819 21 PCR PCR NNP cord-022526-j9kg00qf 3819 22 analysis analysis NN cord-022526-j9kg00qf 3819 23 , , , cord-022526-j9kg00qf 3819 24 appears appear VBZ cord-022526-j9kg00qf 3819 25 to to TO cord-022526-j9kg00qf 3819 26 be be VB cord-022526-j9kg00qf 3819 27 sensitive sensitive JJ cord-022526-j9kg00qf 3819 28 . . . cord-022526-j9kg00qf 3820 1 120 120 CD cord-022526-j9kg00qf 3820 2 Strongyle Strongyle NNP cord-022526-j9kg00qf 3820 3 infections infection NNS cord-022526-j9kg00qf 3820 4 in in IN cord-022526-j9kg00qf 3820 5 horses horse NNS cord-022526-j9kg00qf 3820 6 are be VBP cord-022526-j9kg00qf 3820 7 caused cause VBN cord-022526-j9kg00qf 3820 8 by by IN cord-022526-j9kg00qf 3820 9 two two CD cord-022526-j9kg00qf 3820 10 groups group NNS cord-022526-j9kg00qf 3820 11 of of IN cord-022526-j9kg00qf 3820 12 nematodes nematode NNS cord-022526-j9kg00qf 3820 13 : : : cord-022526-j9kg00qf 3820 14 large large JJ cord-022526-j9kg00qf 3820 15 and and CC cord-022526-j9kg00qf 3820 16 small small JJ cord-022526-j9kg00qf 3820 17 strongyles strongyle NNS cord-022526-j9kg00qf 3820 18 ( ( -LRB- cord-022526-j9kg00qf 3820 19 see see VB cord-022526-j9kg00qf 3820 20 the the DT cord-022526-j9kg00qf 3820 21 section section NN cord-022526-j9kg00qf 3820 22 Cyathostomiasis Cyathostomiasis NNP cord-022526-j9kg00qf 3820 23 ) ) -RRB- cord-022526-j9kg00qf 3820 24 . . . cord-022526-j9kg00qf 3821 1 Large large JJ cord-022526-j9kg00qf 3821 2 strongyles strongyle NNS cord-022526-j9kg00qf 3821 3 that that WDT cord-022526-j9kg00qf 3821 4 are be VBP cord-022526-j9kg00qf 3821 5 pathogenic pathogenic JJ cord-022526-j9kg00qf 3821 6 in in IN cord-022526-j9kg00qf 3821 7 horses horse NNS cord-022526-j9kg00qf 3821 8 include include VBP cord-022526-j9kg00qf 3821 9 Strongylus Strongylus NNP cord-022526-j9kg00qf 3821 10 vulgaris vulgaris NN cord-022526-j9kg00qf 3821 11 , , , cord-022526-j9kg00qf 3821 12 S. S. NNP cord-022526-j9kg00qf 3821 13 edentatus edentatus NN cord-022526-j9kg00qf 3821 14 , , , cord-022526-j9kg00qf 3821 15 and and CC cord-022526-j9kg00qf 3821 16 S. S. NNP cord-022526-j9kg00qf 3821 17 equinus equinus NNP cord-022526-j9kg00qf 3821 18 . . . cord-022526-j9kg00qf 3822 1 Of of IN cord-022526-j9kg00qf 3822 2 these these DT cord-022526-j9kg00qf 3822 3 species specie NNS cord-022526-j9kg00qf 3822 4 , , , cord-022526-j9kg00qf 3822 5 S. S. NNP cord-022526-j9kg00qf 3822 6 vulgaris vulgaris NN cord-022526-j9kg00qf 3822 7 is be VBZ cord-022526-j9kg00qf 3822 8 by by IN cord-022526-j9kg00qf 3822 9 far far RB cord-022526-j9kg00qf 3822 10 the the DT cord-022526-j9kg00qf 3822 11 most most RBS cord-022526-j9kg00qf 3822 12 important important JJ cord-022526-j9kg00qf 3822 13 cause cause NN cord-022526-j9kg00qf 3822 14 of of IN cord-022526-j9kg00qf 3822 15 disease disease NN cord-022526-j9kg00qf 3822 16 in in IN cord-022526-j9kg00qf 3822 17 the the DT cord-022526-j9kg00qf 3822 18 large large JJ cord-022526-j9kg00qf 3822 19 intestine intestine NN cord-022526-j9kg00qf 3822 20 and and CC cord-022526-j9kg00qf 3822 21 in in IN cord-022526-j9kg00qf 3822 22 fact fact NN cord-022526-j9kg00qf 3822 23 is be VBZ cord-022526-j9kg00qf 3822 24 the the DT cord-022526-j9kg00qf 3822 25 most most RBS cord-022526-j9kg00qf 3822 26 pathogenic pathogenic JJ cord-022526-j9kg00qf 3822 27 parasitic parasitic JJ cord-022526-j9kg00qf 3822 28 infection infection NN cord-022526-j9kg00qf 3822 29 in in IN cord-022526-j9kg00qf 3822 30 horses horse NNS cord-022526-j9kg00qf 3822 31 . . . cord-022526-j9kg00qf 3823 1 S. S. NNP cord-022526-j9kg00qf 3823 2 vulgaris vulgaris NN cord-022526-j9kg00qf 3823 3 infection infection NN cord-022526-j9kg00qf 3823 4 in in IN cord-022526-j9kg00qf 3823 5 horses horse NNS cord-022526-j9kg00qf 3823 6 is be VBZ cord-022526-j9kg00qf 3823 7 manifested manifest VBN cord-022526-j9kg00qf 3823 8 clinically clinically RB cord-022526-j9kg00qf 3823 9 by by IN cord-022526-j9kg00qf 3823 10 two two CD cord-022526-j9kg00qf 3823 11 forms form NNS cord-022526-j9kg00qf 3823 12 : : : cord-022526-j9kg00qf 3823 13 acute acute JJ cord-022526-j9kg00qf 3823 14 and and CC cord-022526-j9kg00qf 3823 15 chronic chronic JJ cord-022526-j9kg00qf 3823 16 disease disease NN cord-022526-j9kg00qf 3823 17 . . . cord-022526-j9kg00qf 3824 1 121 121 CD cord-022526-j9kg00qf 3825 1 The the DT cord-022526-j9kg00qf 3825 2 age age NN cord-022526-j9kg00qf 3825 3 and and CC cord-022526-j9kg00qf 3825 4 resistance resistance NN cord-022526-j9kg00qf 3825 5 of of IN cord-022526-j9kg00qf 3825 6 the the DT cord-022526-j9kg00qf 3825 7 host host NN cord-022526-j9kg00qf 3825 8 , , , cord-022526-j9kg00qf 3825 9 the the DT cord-022526-j9kg00qf 3825 10 infective infective JJ cord-022526-j9kg00qf 3825 11 dose dose NN cord-022526-j9kg00qf 3825 12 , , , cord-022526-j9kg00qf 3825 13 and and CC cord-022526-j9kg00qf 3825 14 the the DT cord-022526-j9kg00qf 3825 15 size size NN cord-022526-j9kg00qf 3825 16 and and CC cord-022526-j9kg00qf 3825 17 function function NN cord-022526-j9kg00qf 3825 18 of of IN cord-022526-j9kg00qf 3825 19 the the DT cord-022526-j9kg00qf 3825 20 affected affect VBN cord-022526-j9kg00qf 3825 21 arteries artery NNS cord-022526-j9kg00qf 3825 22 influence influence VBP cord-022526-j9kg00qf 3825 23 the the DT cord-022526-j9kg00qf 3825 24 type type NN cord-022526-j9kg00qf 3825 25 and and CC cord-022526-j9kg00qf 3825 26 degree degree NN cord-022526-j9kg00qf 3825 27 of of IN cord-022526-j9kg00qf 3825 28 disease disease NN cord-022526-j9kg00qf 3825 29 that that WDT cord-022526-j9kg00qf 3825 30 occurs occur VBZ cord-022526-j9kg00qf 3825 31 . . . cord-022526-j9kg00qf 3826 1 Sudden sudden JJ cord-022526-j9kg00qf 3826 2 ingestion ingestion NN cord-022526-j9kg00qf 3826 3 of of IN cord-022526-j9kg00qf 3826 4 large large JJ cord-022526-j9kg00qf 3826 5 numbers number NNS cord-022526-j9kg00qf 3826 6 of of IN cord-022526-j9kg00qf 3826 7 infective infective JJ cord-022526-j9kg00qf 3826 8 larvae larva NNS cord-022526-j9kg00qf 3826 9 by by IN cord-022526-j9kg00qf 3826 10 a a DT cord-022526-j9kg00qf 3826 11 naïve naïve JJ cord-022526-j9kg00qf 3826 12 host host NN cord-022526-j9kg00qf 3826 13 causes cause VBZ cord-022526-j9kg00qf 3826 14 acute acute JJ cord-022526-j9kg00qf 3826 15 strongylosis strongylosis NN cord-022526-j9kg00qf 3826 16 , , , cord-022526-j9kg00qf 3826 17 whereas whereas IN cord-022526-j9kg00qf 3826 18 ingestion ingestion NN cord-022526-j9kg00qf 3826 19 of of IN cord-022526-j9kg00qf 3826 20 fewer few JJR cord-022526-j9kg00qf 3826 21 infective infective JJ cord-022526-j9kg00qf 3826 22 larvae larva NNS cord-022526-j9kg00qf 3826 23 over over IN cord-022526-j9kg00qf 3826 24 a a DT cord-022526-j9kg00qf 3826 25 long long JJ cord-022526-j9kg00qf 3826 26 period period NN cord-022526-j9kg00qf 3826 27 of of IN cord-022526-j9kg00qf 3826 28 time time NN cord-022526-j9kg00qf 3826 29 by by IN cord-022526-j9kg00qf 3826 30 an an DT cord-022526-j9kg00qf 3826 31 older old JJR cord-022526-j9kg00qf 3826 32 , , , cord-022526-j9kg00qf 3826 33 more more RBR cord-022526-j9kg00qf 3826 34 resistant resistant JJ cord-022526-j9kg00qf 3826 35 host host NN cord-022526-j9kg00qf 3826 36 causes cause VBZ cord-022526-j9kg00qf 3826 37 chronic chronic NNP cord-022526-j9kg00qf 3826 38 strongylosis strongylosis NN cord-022526-j9kg00qf 3826 39 . . . cord-022526-j9kg00qf 3827 1 Acute acute JJ cord-022526-j9kg00qf 3827 2 strongylosis strongylosis NN cord-022526-j9kg00qf 3827 3 is be VBZ cord-022526-j9kg00qf 3827 4 more more RBR cord-022526-j9kg00qf 3827 5 likely likely JJ cord-022526-j9kg00qf 3827 6 to to TO cord-022526-j9kg00qf 3827 7 cause cause VB cord-022526-j9kg00qf 3827 8 colic colic NN cord-022526-j9kg00qf 3827 9 than than IN cord-022526-j9kg00qf 3827 10 diarrhea diarrhea NN cord-022526-j9kg00qf 3827 11 and and CC cord-022526-j9kg00qf 3827 12 may may MD cord-022526-j9kg00qf 3827 13 be be VB cord-022526-j9kg00qf 3827 14 rapidly rapidly RB cord-022526-j9kg00qf 3827 15 fatal fatal JJ cord-022526-j9kg00qf 3827 16 . . . cord-022526-j9kg00qf 3828 1 Chronic chronic JJ cord-022526-j9kg00qf 3828 2 strongylosis strongylosis NN cord-022526-j9kg00qf 3828 3 tends tend VBZ cord-022526-j9kg00qf 3828 4 to to TO cord-022526-j9kg00qf 3828 5 cause cause VB cord-022526-j9kg00qf 3828 6 debilitation debilitation NN cord-022526-j9kg00qf 3828 7 and and CC cord-022526-j9kg00qf 3828 8 signs sign NNS cord-022526-j9kg00qf 3828 9 of of IN cord-022526-j9kg00qf 3828 10 colic colic NN cord-022526-j9kg00qf 3828 11 but but CC cord-022526-j9kg00qf 3828 12 may may MD cord-022526-j9kg00qf 3828 13 also also RB cord-022526-j9kg00qf 3828 14 cause cause VB cord-022526-j9kg00qf 3828 15 diarrhea diarrhea NN cord-022526-j9kg00qf 3828 16 . . . cord-022526-j9kg00qf 3829 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3829 2 associated associate VBN cord-022526-j9kg00qf 3829 3 with with IN cord-022526-j9kg00qf 3829 4 acute acute JJ cord-022526-j9kg00qf 3829 5 strongylosis strongylosis NN cord-022526-j9kg00qf 3829 6 occurs occur VBZ cord-022526-j9kg00qf 3829 7 within within IN cord-022526-j9kg00qf 3829 8 several several JJ cord-022526-j9kg00qf 3829 9 days day NNS cord-022526-j9kg00qf 3829 10 of of IN cord-022526-j9kg00qf 3829 11 infection infection NN cord-022526-j9kg00qf 3829 12 and and CC cord-022526-j9kg00qf 3829 13 is be VBZ cord-022526-j9kg00qf 3829 14 likely likely JJ cord-022526-j9kg00qf 3829 15 to to TO cord-022526-j9kg00qf 3829 16 be be VB cord-022526-j9kg00qf 3829 17 caused cause VBN cord-022526-j9kg00qf 3829 18 by by IN cord-022526-j9kg00qf 3829 19 migration migration NN cord-022526-j9kg00qf 3829 20 of of IN cord-022526-j9kg00qf 3829 21 the the DT cord-022526-j9kg00qf 3829 22 larvae larva NNS cord-022526-j9kg00qf 3829 23 through through IN cord-022526-j9kg00qf 3829 24 the the DT cord-022526-j9kg00qf 3829 25 intestinal intestinal JJ cord-022526-j9kg00qf 3829 26 wall wall NN cord-022526-j9kg00qf 3829 27 . . . cord-022526-j9kg00qf 3830 1 Fourth fourth JJ cord-022526-j9kg00qf 3830 2 - - HYPH cord-022526-j9kg00qf 3830 3 stage stage NN cord-022526-j9kg00qf 3830 4 larvae larva NNS cord-022526-j9kg00qf 3830 5 migrate migrate VBP cord-022526-j9kg00qf 3830 6 through through IN cord-022526-j9kg00qf 3830 7 the the DT cord-022526-j9kg00qf 3830 8 mucosa mucosa NN cord-022526-j9kg00qf 3830 9 and and CC cord-022526-j9kg00qf 3830 10 submucosa submucosa NNP cord-022526-j9kg00qf 3830 11 into into IN cord-022526-j9kg00qf 3830 12 the the DT cord-022526-j9kg00qf 3830 13 arterioles arteriole NNS cord-022526-j9kg00qf 3830 14 of of IN cord-022526-j9kg00qf 3830 15 the the DT cord-022526-j9kg00qf 3830 16 intestine intestine NN cord-022526-j9kg00qf 3830 17 , , , cord-022526-j9kg00qf 3830 18 causing cause VBG cord-022526-j9kg00qf 3830 19 mural mural NN cord-022526-j9kg00qf 3830 20 edema edema NN cord-022526-j9kg00qf 3830 21 , , , cord-022526-j9kg00qf 3830 22 hemorrhage hemorrhage NN cord-022526-j9kg00qf 3830 23 , , , cord-022526-j9kg00qf 3830 24 and and CC cord-022526-j9kg00qf 3830 25 infiltration infiltration NN cord-022526-j9kg00qf 3830 26 with with IN cord-022526-j9kg00qf 3830 27 inflammatory inflammatory JJ cord-022526-j9kg00qf 3830 28 cells cell NNS cord-022526-j9kg00qf 3830 29 into into IN cord-022526-j9kg00qf 3830 30 the the DT cord-022526-j9kg00qf 3830 31 intestinal intestinal JJ cord-022526-j9kg00qf 3830 32 wall wall NN cord-022526-j9kg00qf 3830 33 . . . cord-022526-j9kg00qf 3831 1 121,122 121,122 CD cord-022526-j9kg00qf 3831 2 Increased increase VBN cord-022526-j9kg00qf 3831 3 secretion secretion NN cord-022526-j9kg00qf 3831 4 and and CC cord-022526-j9kg00qf 3831 5 decreased decrease VBD cord-022526-j9kg00qf 3831 6 absorption absorption NN cord-022526-j9kg00qf 3831 7 of of IN cord-022526-j9kg00qf 3831 8 fluid fluid NN cord-022526-j9kg00qf 3831 9 and and CC cord-022526-j9kg00qf 3831 10 electrolytes electrolyte NNS cord-022526-j9kg00qf 3831 11 , , , cord-022526-j9kg00qf 3831 12 stimulated stimulate VBN cord-022526-j9kg00qf 3831 13 by by IN cord-022526-j9kg00qf 3831 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 3831 15 mediators mediator NNS cord-022526-j9kg00qf 3831 16 such such JJ cord-022526-j9kg00qf 3831 17 as as IN cord-022526-j9kg00qf 3831 18 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 3831 19 and and CC cord-022526-j9kg00qf 3831 20 histamine histamine NN cord-022526-j9kg00qf 3831 21 , , , cord-022526-j9kg00qf 3831 22 may may MD cord-022526-j9kg00qf 3831 23 play play VB cord-022526-j9kg00qf 3831 24 a a DT cord-022526-j9kg00qf 3831 25 role role NN cord-022526-j9kg00qf 3831 26 in in IN cord-022526-j9kg00qf 3831 27 the the DT cord-022526-j9kg00qf 3831 28 diarrhea diarrhea NN cord-022526-j9kg00qf 3831 29 induced induce VBN cord-022526-j9kg00qf 3831 30 by by IN cord-022526-j9kg00qf 3831 31 S. S. NNP cord-022526-j9kg00qf 3831 32 vulgaris vulgaris NN cord-022526-j9kg00qf 3831 33 . . . cord-022526-j9kg00qf 3832 1 Interstitial interstitial JJ cord-022526-j9kg00qf 3832 2 edema edema NN cord-022526-j9kg00qf 3832 3 and and CC cord-022526-j9kg00qf 3832 4 damage damage NN cord-022526-j9kg00qf 3832 5 to to IN cord-022526-j9kg00qf 3832 6 the the DT cord-022526-j9kg00qf 3832 7 interstitial interstitial JJ cord-022526-j9kg00qf 3832 8 matrix matrix NN cord-022526-j9kg00qf 3832 9 and and CC cord-022526-j9kg00qf 3832 10 mucosa mucosa NN cord-022526-j9kg00qf 3832 11 may may MD cord-022526-j9kg00qf 3832 12 result result VB cord-022526-j9kg00qf 3832 13 from from IN cord-022526-j9kg00qf 3832 14 inflammation inflammation NN cord-022526-j9kg00qf 3832 15 and and CC cord-022526-j9kg00qf 3832 16 migration migration NN cord-022526-j9kg00qf 3832 17 of of IN cord-022526-j9kg00qf 3832 18 the the DT cord-022526-j9kg00qf 3832 19 parasites parasite NNS cord-022526-j9kg00qf 3832 20 , , , cord-022526-j9kg00qf 3832 21 causing cause VBG cord-022526-j9kg00qf 3832 22 increased increase VBN cord-022526-j9kg00qf 3832 23 secretion secretion NN cord-022526-j9kg00qf 3832 24 of of IN cord-022526-j9kg00qf 3832 25 fluid fluid NN cord-022526-j9kg00qf 3832 26 and and CC cord-022526-j9kg00qf 3832 27 albumin albumin NN cord-022526-j9kg00qf 3832 28 loss loss NN cord-022526-j9kg00qf 3832 29 . . . cord-022526-j9kg00qf 3833 1 Abnormal abnormal JJ cord-022526-j9kg00qf 3833 2 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3833 3 motility motility NN cord-022526-j9kg00qf 3833 4 also also RB cord-022526-j9kg00qf 3833 5 may may MD cord-022526-j9kg00qf 3833 6 play play VB cord-022526-j9kg00qf 3833 7 a a DT cord-022526-j9kg00qf 3833 8 role role NN cord-022526-j9kg00qf 3833 9 in in IN cord-022526-j9kg00qf 3833 10 the the DT cord-022526-j9kg00qf 3833 11 development development NN cord-022526-j9kg00qf 3833 12 of of IN cord-022526-j9kg00qf 3833 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3833 14 . . . cord-022526-j9kg00qf 3834 1 Migration migration NN cord-022526-j9kg00qf 3834 2 of of IN cord-022526-j9kg00qf 3834 3 larvae larva NNS cord-022526-j9kg00qf 3834 4 through through IN cord-022526-j9kg00qf 3834 5 the the DT cord-022526-j9kg00qf 3834 6 intestinal intestinal JJ cord-022526-j9kg00qf 3834 7 wall wall NN cord-022526-j9kg00qf 3834 8 early early RB cord-022526-j9kg00qf 3834 9 in in IN cord-022526-j9kg00qf 3834 10 the the DT cord-022526-j9kg00qf 3834 11 course course NN cord-022526-j9kg00qf 3834 12 of of IN cord-022526-j9kg00qf 3834 13 infection infection NN cord-022526-j9kg00qf 3834 14 affects affect VBZ cord-022526-j9kg00qf 3834 15 myoelectric myoelectric JJ cord-022526-j9kg00qf 3834 16 activity activity NN cord-022526-j9kg00qf 3834 17 and and CC cord-022526-j9kg00qf 3834 18 motility motility NN cord-022526-j9kg00qf 3834 19 in in IN cord-022526-j9kg00qf 3834 20 the the DT cord-022526-j9kg00qf 3834 21 large large JJ cord-022526-j9kg00qf 3834 22 intestine intestine NN cord-022526-j9kg00qf 3834 23 and and CC cord-022526-j9kg00qf 3834 24 may may MD cord-022526-j9kg00qf 3834 25 affect affect VB cord-022526-j9kg00qf 3834 26 retention retention NN cord-022526-j9kg00qf 3834 27 of of IN cord-022526-j9kg00qf 3834 28 ingesta ingesta NNP cord-022526-j9kg00qf 3834 29 and and CC cord-022526-j9kg00qf 3834 30 absorption absorption NN cord-022526-j9kg00qf 3834 31 of of IN cord-022526-j9kg00qf 3834 32 fluid fluid NN cord-022526-j9kg00qf 3834 33 . . . cord-022526-j9kg00qf 3835 1 123,124 123,124 CD cord-022526-j9kg00qf 3836 1 The the DT cord-022526-j9kg00qf 3836 2 cause cause NN cord-022526-j9kg00qf 3836 3 of of IN cord-022526-j9kg00qf 3836 4 death death NN cord-022526-j9kg00qf 3836 5 in in IN cord-022526-j9kg00qf 3836 6 acute acute JJ cord-022526-j9kg00qf 3836 7 strongylosis strongylosis NN cord-022526-j9kg00qf 3836 8 has have VBZ cord-022526-j9kg00qf 3836 9 not not RB cord-022526-j9kg00qf 3836 10 been be VBN cord-022526-j9kg00qf 3836 11 addressed address VBN cord-022526-j9kg00qf 3836 12 but but CC cord-022526-j9kg00qf 3836 13 may may MD cord-022526-j9kg00qf 3836 14 be be VB cord-022526-j9kg00qf 3836 15 related relate VBN cord-022526-j9kg00qf 3836 16 to to IN cord-022526-j9kg00qf 3836 17 massive massive JJ cord-022526-j9kg00qf 3836 18 migration migration NN cord-022526-j9kg00qf 3836 19 through through IN cord-022526-j9kg00qf 3836 20 the the DT cord-022526-j9kg00qf 3836 21 vasculature vasculature NN cord-022526-j9kg00qf 3836 22 , , , cord-022526-j9kg00qf 3836 23 causing cause VBG cord-022526-j9kg00qf 3836 24 thrombosis thrombosis NN cord-022526-j9kg00qf 3836 25 with with IN cord-022526-j9kg00qf 3836 26 ischemia ischemia NN cord-022526-j9kg00qf 3836 27 and and CC cord-022526-j9kg00qf 3836 28 infarction infarction NN cord-022526-j9kg00qf 3836 29 of of IN cord-022526-j9kg00qf 3836 30 the the DT cord-022526-j9kg00qf 3836 31 intestine intestine NN cord-022526-j9kg00qf 3836 32 . . . cord-022526-j9kg00qf 3837 1 Chronic chronic JJ cord-022526-j9kg00qf 3837 2 strongylosis strongylosis NN cord-022526-j9kg00qf 3837 3 causes cause VBZ cord-022526-j9kg00qf 3837 4 typical typical JJ cord-022526-j9kg00qf 3837 5 verminous verminous JJ cord-022526-j9kg00qf 3837 6 arteritis arteritis NN cord-022526-j9kg00qf 3837 7 and and CC cord-022526-j9kg00qf 3837 8 is be VBZ cord-022526-j9kg00qf 3837 9 associated associate VBN cord-022526-j9kg00qf 3837 10 more more RBR cord-022526-j9kg00qf 3837 11 commonly commonly RB cord-022526-j9kg00qf 3837 12 with with IN cord-022526-j9kg00qf 3837 13 natural natural JJ cord-022526-j9kg00qf 3837 14 infections infection NNS cord-022526-j9kg00qf 3837 15 in in IN cord-022526-j9kg00qf 3837 16 horses horse NNS cord-022526-j9kg00qf 3837 17 than than IN cord-022526-j9kg00qf 3837 18 with with IN cord-022526-j9kg00qf 3837 19 acute acute JJ cord-022526-j9kg00qf 3837 20 strongylosis strongylosis NN cord-022526-j9kg00qf 3837 21 . . . cord-022526-j9kg00qf 3838 1 121 121 CD cord-022526-j9kg00qf 3838 2 Lesions lesion NNS cord-022526-j9kg00qf 3838 3 of of IN cord-022526-j9kg00qf 3838 4 the the DT cord-022526-j9kg00qf 3838 5 large large JJ cord-022526-j9kg00qf 3838 6 intestinal intestinal JJ cord-022526-j9kg00qf 3838 7 vasculature vasculature NN cord-022526-j9kg00qf 3838 8 caused cause VBN cord-022526-j9kg00qf 3838 9 by by IN cord-022526-j9kg00qf 3838 10 migration migration NN cord-022526-j9kg00qf 3838 11 of of IN cord-022526-j9kg00qf 3838 12 larvae larva NNS cord-022526-j9kg00qf 3838 13 through through IN cord-022526-j9kg00qf 3838 14 the the DT cord-022526-j9kg00qf 3838 15 intima intima NN cord-022526-j9kg00qf 3838 16 are be VBP cord-022526-j9kg00qf 3838 17 characterized characterize VBN cord-022526-j9kg00qf 3838 18 by by IN cord-022526-j9kg00qf 3838 19 thrombus thrombus NN cord-022526-j9kg00qf 3838 20 formation formation NN cord-022526-j9kg00qf 3838 21 , , , cord-022526-j9kg00qf 3838 22 narrowing narrowing NN cord-022526-j9kg00qf 3838 23 of of IN cord-022526-j9kg00qf 3838 24 the the DT cord-022526-j9kg00qf 3838 25 arterial arterial JJ cord-022526-j9kg00qf 3838 26 lumen lumen NN cord-022526-j9kg00qf 3838 27 , , , cord-022526-j9kg00qf 3838 28 fibrosis fibrosis NN cord-022526-j9kg00qf 3838 29 , , , cord-022526-j9kg00qf 3838 30 and and CC cord-022526-j9kg00qf 3838 31 thickening thickening NN cord-022526-j9kg00qf 3838 32 of of IN cord-022526-j9kg00qf 3838 33 the the DT cord-022526-j9kg00qf 3838 34 arterial arterial JJ cord-022526-j9kg00qf 3838 35 wall wall NN cord-022526-j9kg00qf 3838 36 . . . cord-022526-j9kg00qf 3839 1 121,122 121,122 CD cord-022526-j9kg00qf 3839 2 Embolization Embolization NNP cord-022526-j9kg00qf 3839 3 may may MD cord-022526-j9kg00qf 3839 4 occur occur VB cord-022526-j9kg00qf 3839 5 , , , cord-022526-j9kg00qf 3839 6 causing cause VBG cord-022526-j9kg00qf 3839 7 acute acute JJ cord-022526-j9kg00qf 3839 8 segmental segmental JJ cord-022526-j9kg00qf 3839 9 infarction infarction NN cord-022526-j9kg00qf 3839 10 of of IN cord-022526-j9kg00qf 3839 11 the the DT cord-022526-j9kg00qf 3839 12 large large JJ cord-022526-j9kg00qf 3839 13 intestine intestine NN cord-022526-j9kg00qf 3839 14 , , , cord-022526-j9kg00qf 3839 15 but but CC cord-022526-j9kg00qf 3839 16 more more RBR cord-022526-j9kg00qf 3839 17 commonly commonly RB cord-022526-j9kg00qf 3839 18 reduced reduce VBN cord-022526-j9kg00qf 3839 19 blood blood NN cord-022526-j9kg00qf 3839 20 flow flow NN cord-022526-j9kg00qf 3839 21 without without IN cord-022526-j9kg00qf 3839 22 embolization embolization NN cord-022526-j9kg00qf 3839 23 causes cause VBZ cord-022526-j9kg00qf 3839 24 ischemia ischemia NN cord-022526-j9kg00qf 3839 25 and and CC cord-022526-j9kg00qf 3839 26 occasionally occasionally RB cord-022526-j9kg00qf 3839 27 infarction infarction NN cord-022526-j9kg00qf 3839 28 . . . cord-022526-j9kg00qf 3840 1 122,125 122,125 CD cord-022526-j9kg00qf 3840 2 Postmortem Postmortem NNP cord-022526-j9kg00qf 3840 3 examination examination NN cord-022526-j9kg00qf 3840 4 of of IN cord-022526-j9kg00qf 3840 5 horses horse NNS cord-022526-j9kg00qf 3840 6 with with IN cord-022526-j9kg00qf 3840 7 colonic colonic JJ cord-022526-j9kg00qf 3840 8 infarction infarction NN cord-022526-j9kg00qf 3840 9 failed fail VBD cord-022526-j9kg00qf 3840 10 to to TO cord-022526-j9kg00qf 3840 11 reveal reveal VB cord-022526-j9kg00qf 3840 12 embolization embolization NN cord-022526-j9kg00qf 3840 13 as as IN cord-022526-j9kg00qf 3840 14 the the DT cord-022526-j9kg00qf 3840 15 cause cause NN cord-022526-j9kg00qf 3840 16 in in IN cord-022526-j9kg00qf 3840 17 most most JJS cord-022526-j9kg00qf 3840 18 cases case NNS cord-022526-j9kg00qf 3840 19 . . . cord-022526-j9kg00qf 3841 1 125 125 CD cord-022526-j9kg00qf 3842 1 Reduced reduce VBN cord-022526-j9kg00qf 3842 2 blood blood NN cord-022526-j9kg00qf 3842 3 flow flow NN cord-022526-j9kg00qf 3842 4 in in IN cord-022526-j9kg00qf 3842 5 the the DT cord-022526-j9kg00qf 3842 6 tissues tissue NNS cord-022526-j9kg00qf 3842 7 of of IN cord-022526-j9kg00qf 3842 8 the the DT cord-022526-j9kg00qf 3842 9 intestine intestine NN cord-022526-j9kg00qf 3842 10 usually usually RB cord-022526-j9kg00qf 3842 11 results result VBZ cord-022526-j9kg00qf 3842 12 from from IN cord-022526-j9kg00qf 3842 13 narrowing narrow VBG cord-022526-j9kg00qf 3842 14 of of IN cord-022526-j9kg00qf 3842 15 the the DT cord-022526-j9kg00qf 3842 16 arterial arterial JJ cord-022526-j9kg00qf 3842 17 lumen lumen NN cord-022526-j9kg00qf 3842 18 by by IN cord-022526-j9kg00qf 3842 19 the the DT cord-022526-j9kg00qf 3842 20 thrombus thrombus NN cord-022526-j9kg00qf 3842 21 and and CC cord-022526-j9kg00qf 3842 22 formation formation NN cord-022526-j9kg00qf 3842 23 of of IN cord-022526-j9kg00qf 3842 24 microthrombi microthrombi NNP cord-022526-j9kg00qf 3842 25 at at IN cord-022526-j9kg00qf 3842 26 sites site NNS cord-022526-j9kg00qf 3842 27 independent independent JJ cord-022526-j9kg00qf 3842 28 of of IN cord-022526-j9kg00qf 3842 29 the the DT cord-022526-j9kg00qf 3842 30 parasites parasite NNS cord-022526-j9kg00qf 3842 31 . . . cord-022526-j9kg00qf 3843 1 Release release NN cord-022526-j9kg00qf 3843 2 of of IN cord-022526-j9kg00qf 3843 3 vasoconstrictive vasoconstrictive JJ cord-022526-j9kg00qf 3843 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 3843 5 mediators mediator NNS cord-022526-j9kg00qf 3843 6 such such JJ cord-022526-j9kg00qf 3843 7 as as IN cord-022526-j9kg00qf 3843 8 leukotrienes leukotriene NNS cord-022526-j9kg00qf 3843 9 from from IN cord-022526-j9kg00qf 3843 10 platelets platelet NNS cord-022526-j9kg00qf 3843 11 , , , cord-022526-j9kg00qf 3843 12 neutrophils neutrophil NNS cord-022526-j9kg00qf 3843 13 , , , cord-022526-j9kg00qf 3843 14 and and CC cord-022526-j9kg00qf 3843 15 eosinophils eosinophil NNS cord-022526-j9kg00qf 3843 16 and and CC cord-022526-j9kg00qf 3843 17 elaboration elaboration NN cord-022526-j9kg00qf 3843 18 of of IN cord-022526-j9kg00qf 3843 19 parasitic parasitic JJ cord-022526-j9kg00qf 3843 20 antigens antigen NNS cord-022526-j9kg00qf 3843 21 or or CC cord-022526-j9kg00qf 3843 22 toxins toxin NNS cord-022526-j9kg00qf 3843 23 may may MD cord-022526-j9kg00qf 3843 24 cause cause VB cord-022526-j9kg00qf 3843 25 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 3843 26 and and CC cord-022526-j9kg00qf 3843 27 ischemia ischemia NN cord-022526-j9kg00qf 3843 28 . . . cord-022526-j9kg00qf 3844 1 126 126 CD cord-022526-j9kg00qf 3844 2 Horses horse NNS cord-022526-j9kg00qf 3844 3 with with IN cord-022526-j9kg00qf 3844 4 experimental experimental JJ cord-022526-j9kg00qf 3844 5 strongylosis strongylosis NN cord-022526-j9kg00qf 3844 6 were be VBD cord-022526-j9kg00qf 3844 7 found find VBN cord-022526-j9kg00qf 3844 8 to to TO cord-022526-j9kg00qf 3844 9 have have VB cord-022526-j9kg00qf 3844 10 a a DT cord-022526-j9kg00qf 3844 11 50 50 CD cord-022526-j9kg00qf 3844 12 % % NN cord-022526-j9kg00qf 3844 13 reduction reduction NN cord-022526-j9kg00qf 3844 14 of of IN cord-022526-j9kg00qf 3844 15 blood blood NN cord-022526-j9kg00qf 3844 16 flow flow NN cord-022526-j9kg00qf 3844 17 in in IN cord-022526-j9kg00qf 3844 18 the the DT cord-022526-j9kg00qf 3844 19 colonic colonic JJ cord-022526-j9kg00qf 3844 20 vasculature vasculature NN cord-022526-j9kg00qf 3844 21 . . . cord-022526-j9kg00qf 3845 1 127 127 CD cord-022526-j9kg00qf 3845 2 Clearly clearly RB cord-022526-j9kg00qf 3845 3 , , , cord-022526-j9kg00qf 3845 4 reduced reduce VBN cord-022526-j9kg00qf 3845 5 blood blood NN cord-022526-j9kg00qf 3845 6 flow flow NN cord-022526-j9kg00qf 3845 7 is be VBZ cord-022526-j9kg00qf 3845 8 an an DT cord-022526-j9kg00qf 3845 9 important important JJ cord-022526-j9kg00qf 3845 10 effect effect NN cord-022526-j9kg00qf 3845 11 of of IN cord-022526-j9kg00qf 3845 12 chronic chronic JJ cord-022526-j9kg00qf 3845 13 strongylosis strongylosis NN cord-022526-j9kg00qf 3845 14 , , , cord-022526-j9kg00qf 3845 15 but but CC cord-022526-j9kg00qf 3845 16 the the DT cord-022526-j9kg00qf 3845 17 relationship relationship NN cord-022526-j9kg00qf 3845 18 between between IN cord-022526-j9kg00qf 3845 19 blood blood NN cord-022526-j9kg00qf 3845 20 flow flow NN cord-022526-j9kg00qf 3845 21 and and CC cord-022526-j9kg00qf 3845 22 diarrhea diarrhea NN cord-022526-j9kg00qf 3845 23 is be VBZ cord-022526-j9kg00qf 3845 24 unclear unclear JJ cord-022526-j9kg00qf 3845 25 . . . cord-022526-j9kg00qf 3846 1 Disrupted disrupt VBN cord-022526-j9kg00qf 3846 2 motility motility NN cord-022526-j9kg00qf 3846 3 resulting result VBG cord-022526-j9kg00qf 3846 4 from from IN cord-022526-j9kg00qf 3846 5 ischemia ischemia NN cord-022526-j9kg00qf 3846 6 may may MD cord-022526-j9kg00qf 3846 7 lead lead VB cord-022526-j9kg00qf 3846 8 to to IN cord-022526-j9kg00qf 3846 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3846 10 by by IN cord-022526-j9kg00qf 3846 11 reducing reduce VBG cord-022526-j9kg00qf 3846 12 the the DT cord-022526-j9kg00qf 3846 13 retention retention NN cord-022526-j9kg00qf 3846 14 of of IN cord-022526-j9kg00qf 3846 15 ingesta ingesta NNP cord-022526-j9kg00qf 3846 16 and and CC cord-022526-j9kg00qf 3846 17 absorption absorption NN cord-022526-j9kg00qf 3846 18 of of IN cord-022526-j9kg00qf 3846 19 fluid fluid NN cord-022526-j9kg00qf 3846 20 . . . cord-022526-j9kg00qf 3847 1 Acute acute JJ cord-022526-j9kg00qf 3847 2 infarction infarction NN cord-022526-j9kg00qf 3847 3 and and CC cord-022526-j9kg00qf 3847 4 mucosal mucosal JJ cord-022526-j9kg00qf 3847 5 ulceration ulceration NN cord-022526-j9kg00qf 3847 6 have have VBP cord-022526-j9kg00qf 3847 7 been be VBN cord-022526-j9kg00qf 3847 8 found find VBN cord-022526-j9kg00qf 3847 9 to to TO cord-022526-j9kg00qf 3847 10 cause cause VB cord-022526-j9kg00qf 3847 11 severe severe JJ cord-022526-j9kg00qf 3847 12 chronic chronic JJ cord-022526-j9kg00qf 3847 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3847 14 in in IN cord-022526-j9kg00qf 3847 15 naturally naturally RB cord-022526-j9kg00qf 3847 16 infected infect VBN cord-022526-j9kg00qf 3847 17 horses horse NNS cord-022526-j9kg00qf 3847 18 . . . cord-022526-j9kg00qf 3848 1 128 128 CD cord-022526-j9kg00qf 3848 2 Release Release NNP cord-022526-j9kg00qf 3848 3 of of IN cord-022526-j9kg00qf 3848 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 3848 5 mediators mediator NNS cord-022526-j9kg00qf 3848 6 such such JJ cord-022526-j9kg00qf 3848 7 as as IN cord-022526-j9kg00qf 3848 8 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 3848 9 , , , cord-022526-j9kg00qf 3848 10 histamine histamine NN cord-022526-j9kg00qf 3848 11 , , , cord-022526-j9kg00qf 3848 12 and and CC cord-022526-j9kg00qf 3848 13 kinins kinin NNS cord-022526-j9kg00qf 3848 14 from from IN cord-022526-j9kg00qf 3848 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 3848 16 cells cell NNS cord-022526-j9kg00qf 3848 17 associated associate VBN cord-022526-j9kg00qf 3848 18 with with IN cord-022526-j9kg00qf 3848 19 thrombi thrombi NN cord-022526-j9kg00qf 3848 20 and and CC cord-022526-j9kg00qf 3848 21 inflamed inflamed JJ cord-022526-j9kg00qf 3848 22 intestine intestine NN cord-022526-j9kg00qf 3848 23 also also RB cord-022526-j9kg00qf 3848 24 may may MD cord-022526-j9kg00qf 3848 25 affect affect VB cord-022526-j9kg00qf 3848 26 secretion secretion NN cord-022526-j9kg00qf 3848 27 , , , cord-022526-j9kg00qf 3848 28 absorption absorption NN cord-022526-j9kg00qf 3848 29 , , , cord-022526-j9kg00qf 3848 30 and and CC cord-022526-j9kg00qf 3848 31 motility motility NN cord-022526-j9kg00qf 3848 32 , , , cord-022526-j9kg00qf 3848 33 leading lead VBG cord-022526-j9kg00qf 3848 34 to to IN cord-022526-j9kg00qf 3848 35 diarrhea diarrhea NN cord-022526-j9kg00qf 3848 36 . . . cord-022526-j9kg00qf 3849 1 The the DT cord-022526-j9kg00qf 3849 2 clinical clinical JJ cord-022526-j9kg00qf 3849 3 signs sign NNS cord-022526-j9kg00qf 3849 4 of of IN cord-022526-j9kg00qf 3849 5 acute acute JJ cord-022526-j9kg00qf 3849 6 strongylosis strongylosis NN cord-022526-j9kg00qf 3849 7 caused cause VBN cord-022526-j9kg00qf 3849 8 by by IN cord-022526-j9kg00qf 3849 9 S. S. NNP cord-022526-j9kg00qf 3849 10 vulgaris vulgaris NN cord-022526-j9kg00qf 3849 11 infection infection NN cord-022526-j9kg00qf 3849 12 are be VBP cord-022526-j9kg00qf 3849 13 characterized characterize VBN cord-022526-j9kg00qf 3849 14 by by IN cord-022526-j9kg00qf 3849 15 depression depression NN cord-022526-j9kg00qf 3849 16 , , , cord-022526-j9kg00qf 3849 17 moderate moderate JJ cord-022526-j9kg00qf 3849 18 to to IN cord-022526-j9kg00qf 3849 19 severe severe JJ cord-022526-j9kg00qf 3849 20 colic colic NN cord-022526-j9kg00qf 3849 21 , , , cord-022526-j9kg00qf 3849 22 and and CC cord-022526-j9kg00qf 3849 23 fever fever NN cord-022526-j9kg00qf 3849 24 . . . cord-022526-j9kg00qf 3850 1 129 129 CD cord-022526-j9kg00qf 3850 2 Diarrhea diarrhea NN cord-022526-j9kg00qf 3850 3 is be VBZ cord-022526-j9kg00qf 3850 4 less less RBR cord-022526-j9kg00qf 3850 5 often often RB cord-022526-j9kg00qf 3850 6 a a DT cord-022526-j9kg00qf 3850 7 feature feature NN cord-022526-j9kg00qf 3850 8 of of IN cord-022526-j9kg00qf 3850 9 acute acute JJ cord-022526-j9kg00qf 3850 10 strongylosis strongylosis NN cord-022526-j9kg00qf 3850 11 than than IN cord-022526-j9kg00qf 3850 12 is be VBZ cord-022526-j9kg00qf 3850 13 colic colic NN cord-022526-j9kg00qf 3850 14 . . . cord-022526-j9kg00qf 3851 1 121 121 CD cord-022526-j9kg00qf 3852 1 Most Most JJS cord-022526-j9kg00qf 3852 2 cases case NNS cord-022526-j9kg00qf 3852 3 of of IN cord-022526-j9kg00qf 3852 4 acute acute JJ cord-022526-j9kg00qf 3852 5 strongylosis strongylosis NN cord-022526-j9kg00qf 3852 6 occur occur VBP cord-022526-j9kg00qf 3852 7 in in IN cord-022526-j9kg00qf 3852 8 young young JJ cord-022526-j9kg00qf 3852 9 , , , cord-022526-j9kg00qf 3852 10 naïve naïve JJ cord-022526-j9kg00qf 3852 11 horses horse NNS cord-022526-j9kg00qf 3852 12 that that WDT cord-022526-j9kg00qf 3852 13 are be VBP cord-022526-j9kg00qf 3852 14 introduced introduce VBN cord-022526-j9kg00qf 3852 15 to to IN cord-022526-j9kg00qf 3852 16 an an DT cord-022526-j9kg00qf 3852 17 infested infest VBN cord-022526-j9kg00qf 3852 18 environment environment NN cord-022526-j9kg00qf 3852 19 or or CC cord-022526-j9kg00qf 3852 20 are be VBP cord-022526-j9kg00qf 3852 21 inoculated inoculate VBN cord-022526-j9kg00qf 3852 22 experimentally experimentally RB cord-022526-j9kg00qf 3852 23 with with IN cord-022526-j9kg00qf 3852 24 infective infective JJ cord-022526-j9kg00qf 3852 25 larvae larva NNS cord-022526-j9kg00qf 3852 26 . . . cord-022526-j9kg00qf 3853 1 This this DT cord-022526-j9kg00qf 3853 2 form form NN cord-022526-j9kg00qf 3853 3 of of IN cord-022526-j9kg00qf 3853 4 strongylosis strongylosis NN cord-022526-j9kg00qf 3853 5 often often RB cord-022526-j9kg00qf 3853 6 is be VBZ cord-022526-j9kg00qf 3853 7 not not RB cord-022526-j9kg00qf 3853 8 recognized recognize VBN cord-022526-j9kg00qf 3853 9 naturally naturally RB cord-022526-j9kg00qf 3853 10 . . . cord-022526-j9kg00qf 3854 1 Chronic chronic JJ cord-022526-j9kg00qf 3854 2 strongylosis strongylosis NN cord-022526-j9kg00qf 3854 3 , , , cord-022526-j9kg00qf 3854 4 however however RB cord-022526-j9kg00qf 3854 5 , , , cord-022526-j9kg00qf 3854 6 occurs occur VBZ cord-022526-j9kg00qf 3854 7 most most RBS cord-022526-j9kg00qf 3854 8 commonly commonly RB cord-022526-j9kg00qf 3854 9 as as IN cord-022526-j9kg00qf 3854 10 a a DT cord-022526-j9kg00qf 3854 11 natural natural JJ cord-022526-j9kg00qf 3854 12 syndrome syndrome NN cord-022526-j9kg00qf 3854 13 . . . cord-022526-j9kg00qf 3855 1 Weight weight NN cord-022526-j9kg00qf 3855 2 loss loss NN cord-022526-j9kg00qf 3855 3 or or CC cord-022526-j9kg00qf 3855 4 poor poor JJ cord-022526-j9kg00qf 3855 5 weight weight NN cord-022526-j9kg00qf 3855 6 gain gain NN cord-022526-j9kg00qf 3855 7 ; ; : cord-022526-j9kg00qf 3855 8 chronic chronic JJ cord-022526-j9kg00qf 3855 9 , , , cord-022526-j9kg00qf 3855 10 intermittent intermittent JJ cord-022526-j9kg00qf 3855 11 colic colic NN cord-022526-j9kg00qf 3855 12 ; ; : cord-022526-j9kg00qf 3855 13 fever fever NN cord-022526-j9kg00qf 3855 14 ; ; , cord-022526-j9kg00qf 3855 15 poor poor JJ cord-022526-j9kg00qf 3855 16 appetite appetite NN cord-022526-j9kg00qf 3855 17 ; ; : cord-022526-j9kg00qf 3855 18 and and CC cord-022526-j9kg00qf 3855 19 diarrhea diarrhea NN cord-022526-j9kg00qf 3855 20 are be VBP cord-022526-j9kg00qf 3855 21 frequent frequent JJ cord-022526-j9kg00qf 3855 22 signs sign NNS cord-022526-j9kg00qf 3855 23 . . . cord-022526-j9kg00qf 3856 1 121,122 121,122 CD cord-022526-j9kg00qf 3856 2 Diarrhea diarrhea NN cord-022526-j9kg00qf 3856 3 may may MD cord-022526-j9kg00qf 3856 4 be be VB cord-022526-j9kg00qf 3856 5 profuse profuse JJ cord-022526-j9kg00qf 3856 6 and and CC cord-022526-j9kg00qf 3856 7 watery watery JJ cord-022526-j9kg00qf 3856 8 , , , cord-022526-j9kg00qf 3856 9 or or CC cord-022526-j9kg00qf 3856 10 the the DT cord-022526-j9kg00qf 3856 11 feces fece NNS cord-022526-j9kg00qf 3856 12 may may MD cord-022526-j9kg00qf 3856 13 be be VB cord-022526-j9kg00qf 3856 14 soft soft JJ cord-022526-j9kg00qf 3856 15 but but CC cord-022526-j9kg00qf 3856 16 of of IN cord-022526-j9kg00qf 3856 17 normal normal JJ cord-022526-j9kg00qf 3856 18 volume volume NN cord-022526-j9kg00qf 3856 19 . . . cord-022526-j9kg00qf 3857 1 Transrectal transrectal JJ cord-022526-j9kg00qf 3857 2 palpation palpation NN cord-022526-j9kg00qf 3857 3 may may MD cord-022526-j9kg00qf 3857 4 reveal reveal VB cord-022526-j9kg00qf 3857 5 thickening thickening NN cord-022526-j9kg00qf 3857 6 and and CC cord-022526-j9kg00qf 3857 7 fremitus fremitus NN cord-022526-j9kg00qf 3857 8 in in IN cord-022526-j9kg00qf 3857 9 the the DT cord-022526-j9kg00qf 3857 10 cranial cranial JJ cord-022526-j9kg00qf 3857 11 mesenteric mesenteric JJ cord-022526-j9kg00qf 3857 12 artery artery NN cord-022526-j9kg00qf 3857 13 . . . cord-022526-j9kg00qf 3858 1 Young young JJ cord-022526-j9kg00qf 3858 2 horses horse NNS cord-022526-j9kg00qf 3858 3 are be VBP cord-022526-j9kg00qf 3858 4 most most RBS cord-022526-j9kg00qf 3858 5 commonly commonly RB cord-022526-j9kg00qf 3858 6 affected affect VBN cord-022526-j9kg00qf 3858 7 , , , cord-022526-j9kg00qf 3858 8 but but CC cord-022526-j9kg00qf 3858 9 older old JJR cord-022526-j9kg00qf 3858 10 horses horse NNS cord-022526-j9kg00qf 3858 11 also also RB cord-022526-j9kg00qf 3858 12 may may MD cord-022526-j9kg00qf 3858 13 be be VB cord-022526-j9kg00qf 3858 14 affected affect VBN cord-022526-j9kg00qf 3858 15 . . . cord-022526-j9kg00qf 3859 1 Horses horse NNS cord-022526-j9kg00qf 3859 2 with with IN cord-022526-j9kg00qf 3859 3 acute acute JJ cord-022526-j9kg00qf 3859 4 infarction infarction NN cord-022526-j9kg00qf 3859 5 or or CC cord-022526-j9kg00qf 3859 6 large large JJ cord-022526-j9kg00qf 3859 7 intestinal intestinal JJ cord-022526-j9kg00qf 3859 8 ulceration ulceration NN cord-022526-j9kg00qf 3859 9 following follow VBG cord-022526-j9kg00qf 3859 10 chronic chronic JJ cord-022526-j9kg00qf 3859 11 strongylosis strongylosis NN cord-022526-j9kg00qf 3859 12 may may MD cord-022526-j9kg00qf 3859 13 have have VB cord-022526-j9kg00qf 3859 14 signs sign NNS cord-022526-j9kg00qf 3859 15 of of IN cord-022526-j9kg00qf 3859 16 severe severe JJ cord-022526-j9kg00qf 3859 17 abdominal abdominal JJ cord-022526-j9kg00qf 3859 18 pain pain NN cord-022526-j9kg00qf 3859 19 , , , cord-022526-j9kg00qf 3859 20 sepsis sepsis NN cord-022526-j9kg00qf 3859 21 , , , cord-022526-j9kg00qf 3859 22 and and CC cord-022526-j9kg00qf 3859 23 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3859 24 , , , cord-022526-j9kg00qf 3859 25 and and CC cord-022526-j9kg00qf 3859 26 profuse profuse JJ cord-022526-j9kg00qf 3859 27 , , , cord-022526-j9kg00qf 3859 28 watery watery JJ cord-022526-j9kg00qf 3859 29 diarrhea diarrhea NN cord-022526-j9kg00qf 3859 30 is be VBZ cord-022526-j9kg00qf 3859 31 common common JJ cord-022526-j9kg00qf 3859 32 . . . cord-022526-j9kg00qf 3860 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 3860 2 abnormalities abnormality NNS cord-022526-j9kg00qf 3860 3 associated associate VBN cord-022526-j9kg00qf 3860 4 with with IN cord-022526-j9kg00qf 3860 5 strongylosis strongylosis NN cord-022526-j9kg00qf 3860 6 include include VBP cord-022526-j9kg00qf 3860 7 neutrophilic neutrophilic NNP cord-022526-j9kg00qf 3860 8 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 3860 9 and and CC cord-022526-j9kg00qf 3860 10 eosinophilia eosinophilia NN cord-022526-j9kg00qf 3860 11 . . . cord-022526-j9kg00qf 3861 1 [ [ -LRB- cord-022526-j9kg00qf 3861 2 129 129 CD cord-022526-j9kg00qf 3861 3 ] ] -RRB- cord-022526-j9kg00qf 3861 4 [ [ -LRB- cord-022526-j9kg00qf 3861 5 130 130 CD cord-022526-j9kg00qf 3861 6 ] ] -RRB- cord-022526-j9kg00qf 3862 1 [ [ -LRB- cord-022526-j9kg00qf 3862 2 131 131 CD cord-022526-j9kg00qf 3862 3 ] ] -RRB- cord-022526-j9kg00qf 3863 1 Neutrophilia Neutrophilia NNP cord-022526-j9kg00qf 3863 2 appears appear VBZ cord-022526-j9kg00qf 3863 3 to to TO cord-022526-j9kg00qf 3863 4 be be VB cord-022526-j9kg00qf 3863 5 an an DT cord-022526-j9kg00qf 3863 6 early early JJ cord-022526-j9kg00qf 3863 7 event event NN cord-022526-j9kg00qf 3863 8 during during IN cord-022526-j9kg00qf 3863 9 the the DT cord-022526-j9kg00qf 3863 10 course course NN cord-022526-j9kg00qf 3863 11 of of IN cord-022526-j9kg00qf 3863 12 the the DT cord-022526-j9kg00qf 3863 13 disease disease NN cord-022526-j9kg00qf 3863 14 , , , cord-022526-j9kg00qf 3863 15 and and CC cord-022526-j9kg00qf 3863 16 eosinophilia eosinophilia NN cord-022526-j9kg00qf 3863 17 tends tend VBZ cord-022526-j9kg00qf 3863 18 to to TO cord-022526-j9kg00qf 3863 19 appear appear VB cord-022526-j9kg00qf 3863 20 later later RB cord-022526-j9kg00qf 3863 21 . . . cord-022526-j9kg00qf 3864 1 129 129 CD cord-022526-j9kg00qf 3864 2 , , , cord-022526-j9kg00qf 3864 3 131 131 CD cord-022526-j9kg00qf 3864 4 Hyperfibrinogenemia Hyperfibrinogenemia NNP cord-022526-j9kg00qf 3864 5 also also RB cord-022526-j9kg00qf 3864 6 may may MD cord-022526-j9kg00qf 3864 7 occur occur VB cord-022526-j9kg00qf 3864 8 , , , cord-022526-j9kg00qf 3864 9 especially especially RB cord-022526-j9kg00qf 3864 10 later later RB cord-022526-j9kg00qf 3864 11 in in IN cord-022526-j9kg00qf 3864 12 the the DT cord-022526-j9kg00qf 3864 13 course course NN cord-022526-j9kg00qf 3864 14 of of IN cord-022526-j9kg00qf 3864 15 the the DT cord-022526-j9kg00qf 3864 16 disease disease NN cord-022526-j9kg00qf 3864 17 . . . cord-022526-j9kg00qf 3865 1 Serum serum NN cord-022526-j9kg00qf 3865 2 αand αand CC cord-022526-j9kg00qf 3865 3 β β NN cord-022526-j9kg00qf 3865 4 - - HYPH cord-022526-j9kg00qf 3865 5 globulin globulin NNP cord-022526-j9kg00qf 3865 6 and and CC cord-022526-j9kg00qf 3865 7 IgG(T IgG(T NNP cord-022526-j9kg00qf 3865 8 ) ) -RRB- cord-022526-j9kg00qf 3865 9 concentrations concentration NNS cord-022526-j9kg00qf 3865 10 are be VBP cord-022526-j9kg00qf 3865 11 characteristically characteristically RB cord-022526-j9kg00qf 3865 12 elevated elevated JJ cord-022526-j9kg00qf 3865 13 . . . cord-022526-j9kg00qf 3866 1 [ [ -LRB- cord-022526-j9kg00qf 3866 2 130 130 CD cord-022526-j9kg00qf 3866 3 ] ] -RRB- cord-022526-j9kg00qf 3866 4 [ [ -LRB- cord-022526-j9kg00qf 3866 5 131 131 CD cord-022526-j9kg00qf 3866 6 ] ] -RRB- cord-022526-j9kg00qf 3867 1 [ [ -LRB- cord-022526-j9kg00qf 3867 2 132 132 CD cord-022526-j9kg00qf 3867 3 ] ] -RRB- cord-022526-j9kg00qf 3868 1 Horses horse NNS cord-022526-j9kg00qf 3868 2 with with IN cord-022526-j9kg00qf 3868 3 chronic chronic JJ cord-022526-j9kg00qf 3868 4 ulcerative ulcerative JJ cord-022526-j9kg00qf 3868 5 colitis colitis NN cord-022526-j9kg00qf 3868 6 following follow VBG cord-022526-j9kg00qf 3868 7 strongylosis strongylosis NNP cord-022526-j9kg00qf 3868 8 may may MD cord-022526-j9kg00qf 3868 9 exhibit exhibit VB cord-022526-j9kg00qf 3868 10 severe severe JJ cord-022526-j9kg00qf 3868 11 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3868 12 . . . cord-022526-j9kg00qf 3869 1 128 128 CD cord-022526-j9kg00qf 3869 2 Peritoneal Peritoneal NNP cord-022526-j9kg00qf 3869 3 fluid fluid JJ cord-022526-j9kg00qf 3869 4 analysis analysis NN cord-022526-j9kg00qf 3869 5 may may MD cord-022526-j9kg00qf 3869 6 reveal reveal VB cord-022526-j9kg00qf 3869 7 an an DT cord-022526-j9kg00qf 3869 8 elevated elevated JJ cord-022526-j9kg00qf 3869 9 protein protein NN cord-022526-j9kg00qf 3869 10 concentration concentration NN cord-022526-j9kg00qf 3869 11 and and CC cord-022526-j9kg00qf 3869 12 eosinophilia eosinophilia NN cord-022526-j9kg00qf 3869 13 . . . cord-022526-j9kg00qf 3870 1 130 130 CD cord-022526-j9kg00qf 3870 2 , , , cord-022526-j9kg00qf 3870 3 131 131 CD cord-022526-j9kg00qf 3870 4 Tentative tentative JJ cord-022526-j9kg00qf 3870 5 diagnosis diagnosis NN cord-022526-j9kg00qf 3870 6 is be VBZ cord-022526-j9kg00qf 3870 7 based base VBN cord-022526-j9kg00qf 3870 8 on on IN cord-022526-j9kg00qf 3870 9 clinical clinical JJ cord-022526-j9kg00qf 3870 10 signs sign NNS cord-022526-j9kg00qf 3870 11 , , , cord-022526-j9kg00qf 3870 12 hematologic hematologic JJ cord-022526-j9kg00qf 3870 13 abnormalities abnormality NNS cord-022526-j9kg00qf 3870 14 , , , cord-022526-j9kg00qf 3870 15 and and CC cord-022526-j9kg00qf 3870 16 peritoneal peritoneal JJ cord-022526-j9kg00qf 3870 17 fluid fluid NN cord-022526-j9kg00qf 3870 18 analysis analysis NN cord-022526-j9kg00qf 3870 19 . . . cord-022526-j9kg00qf 3871 1 Elevated elevated JJ cord-022526-j9kg00qf 3871 2 serum serum NN cord-022526-j9kg00qf 3871 3 αand αand NN cord-022526-j9kg00qf 3871 4 β β NN cord-022526-j9kg00qf 3871 5 - - HYPH cord-022526-j9kg00qf 3871 6 globulin globulin NN cord-022526-j9kg00qf 3871 7 concentrations concentration NNS cord-022526-j9kg00qf 3871 8 and and CC cord-022526-j9kg00qf 3871 9 IgG(T igg(t NN cord-022526-j9kg00qf 3871 10 ) ) -RRB- cord-022526-j9kg00qf 3871 11 concentration concentration NN cord-022526-j9kg00qf 3871 12 support support VBP cord-022526-j9kg00qf 3871 13 the the DT cord-022526-j9kg00qf 3871 14 diagnosis diagnosis NN cord-022526-j9kg00qf 3871 15 . . . cord-022526-j9kg00qf 3872 1 132 132 CD cord-022526-j9kg00qf 3872 2 Fecal fecal JJ cord-022526-j9kg00qf 3872 3 analysis analysis NN cord-022526-j9kg00qf 3872 4 may may MD cord-022526-j9kg00qf 3872 5 reveal reveal VB cord-022526-j9kg00qf 3872 6 strongyle strongyle NN cord-022526-j9kg00qf 3872 7 eggs egg NNS cord-022526-j9kg00qf 3872 8 , , , cord-022526-j9kg00qf 3872 9 but but CC cord-022526-j9kg00qf 3872 10 fecal fecal JJ cord-022526-j9kg00qf 3872 11 egg egg NN cord-022526-j9kg00qf 3872 12 counts count NNS cord-022526-j9kg00qf 3872 13 are be VBP cord-022526-j9kg00qf 3872 14 often often RB cord-022526-j9kg00qf 3872 15 unreliable unreliable JJ cord-022526-j9kg00qf 3872 16 because because IN cord-022526-j9kg00qf 3872 17 nonpatent nonpatent NNP cord-022526-j9kg00qf 3872 18 larvae larva NNS cord-022526-j9kg00qf 3872 19 cause cause VBP cord-022526-j9kg00qf 3872 20 the the DT cord-022526-j9kg00qf 3872 21 disease disease NN cord-022526-j9kg00qf 3872 22 . . . cord-022526-j9kg00qf 3873 1 Appropriate appropriate JJ cord-022526-j9kg00qf 3873 2 preventive preventive JJ cord-022526-j9kg00qf 3873 3 measures measure NNS cord-022526-j9kg00qf 3873 4 are be VBP cord-022526-j9kg00qf 3873 5 important important JJ cord-022526-j9kg00qf 3873 6 in in IN cord-022526-j9kg00qf 3873 7 controlling control VBG cord-022526-j9kg00qf 3873 8 this this DT cord-022526-j9kg00qf 3873 9 disease disease NN cord-022526-j9kg00qf 3873 10 , , , cord-022526-j9kg00qf 3873 11 including include VBG cord-022526-j9kg00qf 3873 12 management management NN cord-022526-j9kg00qf 3873 13 procedures procedure NNS cord-022526-j9kg00qf 3873 14 such such JJ cord-022526-j9kg00qf 3873 15 as as IN cord-022526-j9kg00qf 3873 16 preventing prevent VBG cord-022526-j9kg00qf 3873 17 overcrowding overcrowding NN cord-022526-j9kg00qf 3873 18 , , , cord-022526-j9kg00qf 3873 19 reducing reduce VBG cord-022526-j9kg00qf 3873 20 exposure exposure NN cord-022526-j9kg00qf 3873 21 of of IN cord-022526-j9kg00qf 3873 22 susceptible susceptible JJ cord-022526-j9kg00qf 3873 23 individuals individual NNS cord-022526-j9kg00qf 3873 24 , , , cord-022526-j9kg00qf 3873 25 and and CC cord-022526-j9kg00qf 3873 26 instituting institute VBG cord-022526-j9kg00qf 3873 27 proper proper JJ cord-022526-j9kg00qf 3873 28 deworming deworme VBG cord-022526-j9kg00qf 3873 29 schedules schedule NNS cord-022526-j9kg00qf 3873 30 . . . cord-022526-j9kg00qf 3874 1 Ivermectin Ivermectin NNP cord-022526-j9kg00qf 3874 2 is be VBZ cord-022526-j9kg00qf 3874 3 the the DT cord-022526-j9kg00qf 3874 4 preferred preferred JJ cord-022526-j9kg00qf 3874 5 anthelmintic anthelmintic NN cord-022526-j9kg00qf 3874 6 used use VBN cord-022526-j9kg00qf 3874 7 to to TO cord-022526-j9kg00qf 3874 8 control control VB cord-022526-j9kg00qf 3874 9 strongylosis strongylosis NN cord-022526-j9kg00qf 3874 10 in in IN cord-022526-j9kg00qf 3874 11 horses horse NNS cord-022526-j9kg00qf 3874 12 . . . cord-022526-j9kg00qf 3875 1 Monitoring monitor VBG cord-022526-j9kg00qf 3875 2 fecal fecal JJ cord-022526-j9kg00qf 3875 3 egg egg NN cord-022526-j9kg00qf 3875 4 counts count VBZ cord-022526-j9kg00qf 3875 5 as as IN cord-022526-j9kg00qf 3875 6 a a DT cord-022526-j9kg00qf 3875 7 means means NN cord-022526-j9kg00qf 3875 8 of of IN cord-022526-j9kg00qf 3875 9 evaluating evaluate VBG cord-022526-j9kg00qf 3875 10 the the DT cord-022526-j9kg00qf 3875 11 efficacy efficacy NN cord-022526-j9kg00qf 3875 12 of of IN cord-022526-j9kg00qf 3875 13 parasite parasite NN cord-022526-j9kg00qf 3875 14 control control NN cord-022526-j9kg00qf 3875 15 measures measure NNS cord-022526-j9kg00qf 3875 16 is be VBZ cord-022526-j9kg00qf 3875 17 recommended recommend VBN cord-022526-j9kg00qf 3875 18 . . . cord-022526-j9kg00qf 3876 1 Infection infection NN cord-022526-j9kg00qf 3876 2 with with IN cord-022526-j9kg00qf 3876 3 small small JJ cord-022526-j9kg00qf 3876 4 strongyles strongyle NNS cord-022526-j9kg00qf 3876 5 ( ( -LRB- cord-022526-j9kg00qf 3876 6 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3876 7 ) ) -RRB- cord-022526-j9kg00qf 3876 8 is be VBZ cord-022526-j9kg00qf 3876 9 well well RB cord-022526-j9kg00qf 3876 10 recognized recognize VBN cord-022526-j9kg00qf 3876 11 as as IN cord-022526-j9kg00qf 3876 12 a a DT cord-022526-j9kg00qf 3876 13 cause cause NN cord-022526-j9kg00qf 3876 14 of of IN cord-022526-j9kg00qf 3876 15 diarrhea diarrhea NN cord-022526-j9kg00qf 3876 16 and and CC cord-022526-j9kg00qf 3876 17 large large JJ cord-022526-j9kg00qf 3876 18 intestinal intestinal JJ cord-022526-j9kg00qf 3876 19 disease disease NN cord-022526-j9kg00qf 3876 20 in in IN cord-022526-j9kg00qf 3876 21 horses horse NNS cord-022526-j9kg00qf 3876 22 of of IN cord-022526-j9kg00qf 3876 23 all all DT cord-022526-j9kg00qf 3876 24 ages age NNS cord-022526-j9kg00qf 3876 25 . . . cord-022526-j9kg00qf 3877 1 [ [ -LRB- cord-022526-j9kg00qf 3877 2 133 133 CD cord-022526-j9kg00qf 3877 3 ] ] -RRB- cord-022526-j9kg00qf 3877 4 [ [ -LRB- cord-022526-j9kg00qf 3877 5 134 134 CD cord-022526-j9kg00qf 3877 6 ] ] -RRB- cord-022526-j9kg00qf 3877 7 [ [ -LRB- cord-022526-j9kg00qf 3877 8 135 135 CD cord-022526-j9kg00qf 3877 9 ] ] -RRB- cord-022526-j9kg00qf 3877 10 [ [ -LRB- cord-022526-j9kg00qf 3877 11 136 136 CD cord-022526-j9kg00qf 3877 12 ] ] -RRB- cord-022526-j9kg00qf 3877 13 [ [ -LRB- cord-022526-j9kg00qf 3877 14 137 137 CD cord-022526-j9kg00qf 3877 15 ] ] -RRB- cord-022526-j9kg00qf 3878 1 [ [ -LRB- cord-022526-j9kg00qf 3878 2 138 138 CD cord-022526-j9kg00qf 3878 3 ] ] -RRB- cord-022526-j9kg00qf 3879 1 Clinical clinical JJ cord-022526-j9kg00qf 3879 2 disease disease NN cord-022526-j9kg00qf 3879 3 is be VBZ cord-022526-j9kg00qf 3879 4 caused cause VBN cord-022526-j9kg00qf 3879 5 by by IN cord-022526-j9kg00qf 3879 6 intramural intramural JJ cord-022526-j9kg00qf 3879 7 larval larval JJ cord-022526-j9kg00qf 3879 8 stages stage NNS cord-022526-j9kg00qf 3879 9 . . . cord-022526-j9kg00qf 3880 1 The the DT cord-022526-j9kg00qf 3880 2 cyathostome cyathostome NN cord-022526-j9kg00qf 3880 3 life life NN cord-022526-j9kg00qf 3880 4 cycle cycle NN cord-022526-j9kg00qf 3880 5 requires require VBZ cord-022526-j9kg00qf 3880 6 migration migration NN cord-022526-j9kg00qf 3880 7 by by IN cord-022526-j9kg00qf 3880 8 fourth fourth JJ cord-022526-j9kg00qf 3880 9 - - HYPH cord-022526-j9kg00qf 3880 10 stage stage NN cord-022526-j9kg00qf 3880 11 larvae larva NNS cord-022526-j9kg00qf 3880 12 through through IN cord-022526-j9kg00qf 3880 13 the the DT cord-022526-j9kg00qf 3880 14 mucosa mucosa NN cord-022526-j9kg00qf 3880 15 of of IN cord-022526-j9kg00qf 3880 16 the the DT cord-022526-j9kg00qf 3880 17 large large JJ cord-022526-j9kg00qf 3880 18 intestine intestine NN cord-022526-j9kg00qf 3880 19 and and CC cord-022526-j9kg00qf 3880 20 may may MD cord-022526-j9kg00qf 3880 21 include include VB cord-022526-j9kg00qf 3880 22 a a DT cord-022526-j9kg00qf 3880 23 period period NN cord-022526-j9kg00qf 3880 24 of of IN cord-022526-j9kg00qf 3880 25 hypobiosis hypobiosis NN cord-022526-j9kg00qf 3880 26 during during IN cord-022526-j9kg00qf 3880 27 which which WDT cord-022526-j9kg00qf 3880 28 the the DT cord-022526-j9kg00qf 3880 29 larvae larva NNS cord-022526-j9kg00qf 3880 30 remain remain VBP cord-022526-j9kg00qf 3880 31 encysted encysted JJ cord-022526-j9kg00qf 3880 32 within within IN cord-022526-j9kg00qf 3880 33 the the DT cord-022526-j9kg00qf 3880 34 mucosal mucosal JJ cord-022526-j9kg00qf 3880 35 layer layer NN cord-022526-j9kg00qf 3880 36 of of IN cord-022526-j9kg00qf 3880 37 the the DT cord-022526-j9kg00qf 3880 38 large large JJ cord-022526-j9kg00qf 3880 39 intestine intestine NN cord-022526-j9kg00qf 3880 40 . . . cord-022526-j9kg00qf 3881 1 After after IN cord-022526-j9kg00qf 3881 2 a a DT cord-022526-j9kg00qf 3881 3 period period NN cord-022526-j9kg00qf 3881 4 of of IN cord-022526-j9kg00qf 3881 5 hypobiosis hypobiosis NN cord-022526-j9kg00qf 3881 6 the the DT cord-022526-j9kg00qf 3881 7 larvae larva NNS cord-022526-j9kg00qf 3881 8 emerge emerge VBP cord-022526-j9kg00qf 3881 9 in in IN cord-022526-j9kg00qf 3881 10 response response NN cord-022526-j9kg00qf 3881 11 to to IN cord-022526-j9kg00qf 3881 12 a a DT cord-022526-j9kg00qf 3881 13 largely largely RB cord-022526-j9kg00qf 3881 14 unknown unknown JJ cord-022526-j9kg00qf 3881 15 stimulus stimulus NN cord-022526-j9kg00qf 3881 16 . . . cord-022526-j9kg00qf 3882 1 Most Most JJS cord-022526-j9kg00qf 3882 2 cases case NNS cord-022526-j9kg00qf 3882 3 occur occur VBP cord-022526-j9kg00qf 3882 4 when when WRB cord-022526-j9kg00qf 3882 5 larval larval JJ cord-022526-j9kg00qf 3882 6 emergence emergence NN cord-022526-j9kg00qf 3882 7 takes take VBZ cord-022526-j9kg00qf 3882 8 place place NN cord-022526-j9kg00qf 3882 9 , , , cord-022526-j9kg00qf 3882 10 classically classically RB cord-022526-j9kg00qf 3882 11 in in IN cord-022526-j9kg00qf 3882 12 the the DT cord-022526-j9kg00qf 3882 13 late late JJ cord-022526-j9kg00qf 3882 14 winter winter NN cord-022526-j9kg00qf 3882 15 and and CC cord-022526-j9kg00qf 3882 16 spring spring NN cord-022526-j9kg00qf 3882 17 in in IN cord-022526-j9kg00qf 3882 18 the the DT cord-022526-j9kg00qf 3882 19 northern northern JJ cord-022526-j9kg00qf 3882 20 temperate temperate JJ cord-022526-j9kg00qf 3882 21 zones zone NNS cord-022526-j9kg00qf 3882 22 when when WRB cord-022526-j9kg00qf 3882 23 larvae larva NNS cord-022526-j9kg00qf 3882 24 are be VBP cord-022526-j9kg00qf 3882 25 expected expect VBN cord-022526-j9kg00qf 3882 26 to to TO cord-022526-j9kg00qf 3882 27 emerge emerge VB cord-022526-j9kg00qf 3882 28 and and CC cord-022526-j9kg00qf 3882 29 in in IN cord-022526-j9kg00qf 3882 30 the the DT cord-022526-j9kg00qf 3882 31 late late JJ cord-022526-j9kg00qf 3882 32 fall fall NN cord-022526-j9kg00qf 3882 33 or or CC cord-022526-j9kg00qf 3882 34 winter winter NN cord-022526-j9kg00qf 3882 35 months month NNS cord-022526-j9kg00qf 3882 36 in in IN cord-022526-j9kg00qf 3882 37 the the DT cord-022526-j9kg00qf 3882 38 southeastern southeastern JJ cord-022526-j9kg00qf 3882 39 United United NNP cord-022526-j9kg00qf 3882 40 States States NNP cord-022526-j9kg00qf 3882 41 and and CC cord-022526-j9kg00qf 3882 42 subtropical subtropical JJ cord-022526-j9kg00qf 3882 43 regions region NNS cord-022526-j9kg00qf 3882 44 . . . cord-022526-j9kg00qf 3883 1 133 133 CD cord-022526-j9kg00qf 3884 1 Sudden sudden JJ cord-022526-j9kg00qf 3884 2 emergence emergence NN cord-022526-j9kg00qf 3884 3 of of IN cord-022526-j9kg00qf 3884 4 encysted encysted JJ cord-022526-j9kg00qf 3884 5 larvae larva NNS cord-022526-j9kg00qf 3884 6 causes cause VBZ cord-022526-j9kg00qf 3884 7 the the DT cord-022526-j9kg00qf 3884 8 mucosal mucosal JJ cord-022526-j9kg00qf 3884 9 injury injury NN cord-022526-j9kg00qf 3884 10 , , , cord-022526-j9kg00qf 3884 11 ulceration ulceration NN cord-022526-j9kg00qf 3884 12 , , , cord-022526-j9kg00qf 3884 13 and and CC cord-022526-j9kg00qf 3884 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 3884 15 reaction reaction NN cord-022526-j9kg00qf 3884 16 responsible responsible JJ cord-022526-j9kg00qf 3884 17 in in IN cord-022526-j9kg00qf 3884 18 large large JJ cord-022526-j9kg00qf 3884 19 part part NN cord-022526-j9kg00qf 3884 20 for for IN cord-022526-j9kg00qf 3884 21 the the DT cord-022526-j9kg00qf 3884 22 clinical clinical JJ cord-022526-j9kg00qf 3884 23 disease disease NN cord-022526-j9kg00qf 3884 24 . . . cord-022526-j9kg00qf 3885 1 133 133 CD cord-022526-j9kg00qf 3886 1 , , , cord-022526-j9kg00qf 3886 2 139 139 CD cord-022526-j9kg00qf 3887 1 However however RB cord-022526-j9kg00qf 3887 2 , , , cord-022526-j9kg00qf 3887 3 migration migration NN cord-022526-j9kg00qf 3887 4 of of IN cord-022526-j9kg00qf 3887 5 the the DT cord-022526-j9kg00qf 3887 6 larvae larva NNS cord-022526-j9kg00qf 3887 7 as as IN cord-022526-j9kg00qf 3887 8 they -PRON- PRP cord-022526-j9kg00qf 3887 9 penetrate penetrate VBP cord-022526-j9kg00qf 3887 10 the the DT cord-022526-j9kg00qf 3887 11 mucosa mucosa NN cord-022526-j9kg00qf 3887 12 affects affect VBZ cord-022526-j9kg00qf 3887 13 motility motility NN cord-022526-j9kg00qf 3887 14 patterns pattern NNS cord-022526-j9kg00qf 3887 15 and and CC cord-022526-j9kg00qf 3887 16 can can MD cord-022526-j9kg00qf 3887 17 cause cause VB cord-022526-j9kg00qf 3887 18 inflammation inflammation NN cord-022526-j9kg00qf 3887 19 that that WDT cord-022526-j9kg00qf 3887 20 may may MD cord-022526-j9kg00qf 3887 21 contribute contribute VB cord-022526-j9kg00qf 3887 22 to to IN cord-022526-j9kg00qf 3887 23 diarrhea diarrhea NN cord-022526-j9kg00qf 3887 24 . . . cord-022526-j9kg00qf 3888 1 139 139 CD cord-022526-j9kg00qf 3888 2 Chronic Chronic NNP cord-022526-j9kg00qf 3888 3 , , , cord-022526-j9kg00qf 3888 4 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3888 5 , , , cord-022526-j9kg00qf 3888 6 granulomatous granulomatous JJ cord-022526-j9kg00qf 3888 7 colitis colitis NN cord-022526-j9kg00qf 3888 8 and and CC cord-022526-j9kg00qf 3888 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3888 10 with with IN cord-022526-j9kg00qf 3888 11 histopathologic histopathologic JJ cord-022526-j9kg00qf 3888 12 evidence evidence NN cord-022526-j9kg00qf 3888 13 of of IN cord-022526-j9kg00qf 3888 14 hypobiotic hypobiotic NNP cord-022526-j9kg00qf 3888 15 cyathostome cyathostome NNP cord-022526-j9kg00qf 3888 16 larvae larva NNS cord-022526-j9kg00qf 3888 17 in in IN cord-022526-j9kg00qf 3888 18 the the DT cord-022526-j9kg00qf 3888 19 large large JJ cord-022526-j9kg00qf 3888 20 intestine intestine NN cord-022526-j9kg00qf 3888 21 have have VBP cord-022526-j9kg00qf 3888 22 been be VBN cord-022526-j9kg00qf 3888 23 reported report VBN cord-022526-j9kg00qf 3888 24 in in IN cord-022526-j9kg00qf 3888 25 two two CD cord-022526-j9kg00qf 3888 26 horses horse NNS cord-022526-j9kg00qf 3888 27 during during IN cord-022526-j9kg00qf 3888 28 a a DT cord-022526-j9kg00qf 3888 29 period period NN cord-022526-j9kg00qf 3888 30 in in IN cord-022526-j9kg00qf 3888 31 which which WDT cord-022526-j9kg00qf 3888 32 emergence emergence NN cord-022526-j9kg00qf 3888 33 of of IN cord-022526-j9kg00qf 3888 34 larvae larva NNS cord-022526-j9kg00qf 3888 35 would would MD cord-022526-j9kg00qf 3888 36 not not RB cord-022526-j9kg00qf 3888 37 be be VB cord-022526-j9kg00qf 3888 38 expected expect VBN cord-022526-j9kg00qf 3888 39 to to TO cord-022526-j9kg00qf 3888 40 occur occur VB cord-022526-j9kg00qf 3888 41 ( ( -LRB- cord-022526-j9kg00qf 3888 42 early early JJ cord-022526-j9kg00qf 3888 43 winter winter NN cord-022526-j9kg00qf 3888 44 ) ) -RRB- cord-022526-j9kg00qf 3888 45 . . . cord-022526-j9kg00qf 3889 1 133 133 CD cord-022526-j9kg00qf 3889 2 Natural natural JJ cord-022526-j9kg00qf 3889 3 emergence emergence NN cord-022526-j9kg00qf 3889 4 of of IN cord-022526-j9kg00qf 3889 5 cyathostome cyathostome NN cord-022526-j9kg00qf 3889 6 larvae larva NNS cord-022526-j9kg00qf 3889 7 causes cause VBZ cord-022526-j9kg00qf 3889 8 fibrinous fibrinous JJ cord-022526-j9kg00qf 3889 9 inflammation inflammation NN cord-022526-j9kg00qf 3889 10 of of IN cord-022526-j9kg00qf 3889 11 the the DT cord-022526-j9kg00qf 3889 12 large large JJ cord-022526-j9kg00qf 3889 13 intestine intestine NN cord-022526-j9kg00qf 3889 14 , , , cord-022526-j9kg00qf 3889 15 focal focal JJ cord-022526-j9kg00qf 3889 16 necrosis necrosis NN cord-022526-j9kg00qf 3889 17 , , , cord-022526-j9kg00qf 3889 18 mural mural NN cord-022526-j9kg00qf 3889 19 hemorrhage hemorrhage NN cord-022526-j9kg00qf 3889 20 , , , cord-022526-j9kg00qf 3889 21 and and CC cord-022526-j9kg00qf 3889 22 ulceration ulceration NN cord-022526-j9kg00qf 3889 23 of of IN cord-022526-j9kg00qf 3889 24 the the DT cord-022526-j9kg00qf 3889 25 large large JJ cord-022526-j9kg00qf 3889 26 intestinal intestinal JJ cord-022526-j9kg00qf 3889 27 mucosa mucosa NN cord-022526-j9kg00qf 3889 28 , , , cord-022526-j9kg00qf 3889 29 which which WDT cord-022526-j9kg00qf 3889 30 even even RB cord-022526-j9kg00qf 3889 31 may may MD cord-022526-j9kg00qf 3889 32 result result VB cord-022526-j9kg00qf 3889 33 in in IN cord-022526-j9kg00qf 3889 34 bleeding bleed VBG cord-022526-j9kg00qf 3889 35 into into IN cord-022526-j9kg00qf 3889 36 the the DT cord-022526-j9kg00qf 3889 37 lumen lumen NN cord-022526-j9kg00qf 3889 38 . . . cord-022526-j9kg00qf 3890 1 Mild mild JJ cord-022526-j9kg00qf 3890 2 to to TO cord-022526-j9kg00qf 3890 3 moderate moderate VB cord-022526-j9kg00qf 3890 4 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 3890 5 and and CC cord-022526-j9kg00qf 3890 6 mononuclear mononuclear JJ cord-022526-j9kg00qf 3890 7 inflammation inflammation NN cord-022526-j9kg00qf 3890 8 of of IN cord-022526-j9kg00qf 3890 9 the the DT cord-022526-j9kg00qf 3890 10 lamina lamina JJ cord-022526-j9kg00qf 3890 11 propria propria NN cord-022526-j9kg00qf 3890 12 occurs occur VBZ cord-022526-j9kg00qf 3890 13 , , , cord-022526-j9kg00qf 3890 14 and and CC cord-022526-j9kg00qf 3890 15 moderate moderate JJ cord-022526-j9kg00qf 3890 16 to to IN cord-022526-j9kg00qf 3890 17 severe severe JJ cord-022526-j9kg00qf 3890 18 interstitial interstitial JJ cord-022526-j9kg00qf 3890 19 edema edema NN cord-022526-j9kg00qf 3890 20 frequently frequently RB cord-022526-j9kg00qf 3890 21 occurs occur VBZ cord-022526-j9kg00qf 3890 22 . . . cord-022526-j9kg00qf 3891 1 122 122 CD cord-022526-j9kg00qf 3891 2 , , , cord-022526-j9kg00qf 3891 3 139 139 CD cord-022526-j9kg00qf 3891 4 Colonic colonic JJ cord-022526-j9kg00qf 3891 5 inflammation inflammation NN cord-022526-j9kg00qf 3891 6 and and CC cord-022526-j9kg00qf 3891 7 interstitial interstitial JJ cord-022526-j9kg00qf 3891 8 edema edema NN cord-022526-j9kg00qf 3891 9 may may MD cord-022526-j9kg00qf 3891 10 contribute contribute VB cord-022526-j9kg00qf 3891 11 to to IN cord-022526-j9kg00qf 3891 12 the the DT cord-022526-j9kg00qf 3891 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3891 14 , , , cord-022526-j9kg00qf 3891 15 along along IN cord-022526-j9kg00qf 3891 16 with with IN cord-022526-j9kg00qf 3891 17 the the DT cord-022526-j9kg00qf 3891 18 loss loss NN cord-022526-j9kg00qf 3891 19 of of IN cord-022526-j9kg00qf 3891 20 the the DT cord-022526-j9kg00qf 3891 21 mucosal mucosal JJ cord-022526-j9kg00qf 3891 22 barrier barrier NN cord-022526-j9kg00qf 3891 23 , , , cord-022526-j9kg00qf 3891 24 by by IN cord-022526-j9kg00qf 3891 25 causing cause VBG cord-022526-j9kg00qf 3891 26 increased increase VBN cord-022526-j9kg00qf 3891 27 active active JJ cord-022526-j9kg00qf 3891 28 and and CC cord-022526-j9kg00qf 3891 29 passive passive JJ cord-022526-j9kg00qf 3891 30 secretion secretion NN cord-022526-j9kg00qf 3891 31 of of IN cord-022526-j9kg00qf 3891 32 fluid fluid NN cord-022526-j9kg00qf 3891 33 , , , cord-022526-j9kg00qf 3891 34 electrolytes electrolyte NNS cord-022526-j9kg00qf 3891 35 , , , cord-022526-j9kg00qf 3891 36 and and CC cord-022526-j9kg00qf 3891 37 protein protein NN cord-022526-j9kg00qf 3891 38 . . . cord-022526-j9kg00qf 3892 1 Protein protein NN cord-022526-j9kg00qf 3892 2 loss loss NN cord-022526-j9kg00qf 3892 3 is be VBZ cord-022526-j9kg00qf 3892 4 often often RB cord-022526-j9kg00qf 3892 5 significant significant JJ cord-022526-j9kg00qf 3892 6 , , , cord-022526-j9kg00qf 3892 7 resulting result VBG cord-022526-j9kg00qf 3892 8 in in IN cord-022526-j9kg00qf 3892 9 profound profound JJ cord-022526-j9kg00qf 3892 10 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3892 11 and and CC cord-022526-j9kg00qf 3892 12 interstitial interstitial JJ cord-022526-j9kg00qf 3892 13 edema edema NN cord-022526-j9kg00qf 3892 14 of of IN cord-022526-j9kg00qf 3892 15 skin skin NN cord-022526-j9kg00qf 3892 16 and and CC cord-022526-j9kg00qf 3892 17 other other JJ cord-022526-j9kg00qf 3892 18 organs organ NNS cord-022526-j9kg00qf 3892 19 . . . cord-022526-j9kg00qf 3893 1 Chronic chronic JJ cord-022526-j9kg00qf 3893 2 , , , cord-022526-j9kg00qf 3893 3 granulomatous granulomatous JJ cord-022526-j9kg00qf 3893 4 colitis colitis NN cord-022526-j9kg00qf 3893 5 has have VBZ cord-022526-j9kg00qf 3893 6 been be VBN cord-022526-j9kg00qf 3893 7 reported report VBN cord-022526-j9kg00qf 3893 8 to to TO cord-022526-j9kg00qf 3893 9 occur occur VB cord-022526-j9kg00qf 3893 10 in in IN cord-022526-j9kg00qf 3893 11 response response NN cord-022526-j9kg00qf 3893 12 to to IN cord-022526-j9kg00qf 3893 13 encysted encysted JJ cord-022526-j9kg00qf 3893 14 larvae larva NNS cord-022526-j9kg00qf 3893 15 and and CC cord-022526-j9kg00qf 3893 16 may may MD cord-022526-j9kg00qf 3893 17 cause cause VB cord-022526-j9kg00qf 3893 18 diarrhea diarrhea NN cord-022526-j9kg00qf 3893 19 by by IN cord-022526-j9kg00qf 3893 20 increased increase VBN cord-022526-j9kg00qf 3893 21 secretion secretion NN cord-022526-j9kg00qf 3893 22 following follow VBG cord-022526-j9kg00qf 3893 23 granulomatous granulomatous JJ cord-022526-j9kg00qf 3893 24 inflammation inflammation NN cord-022526-j9kg00qf 3893 25 or or CC cord-022526-j9kg00qf 3893 26 disruption disruption NN cord-022526-j9kg00qf 3893 27 of of IN cord-022526-j9kg00qf 3893 28 the the DT cord-022526-j9kg00qf 3893 29 interstitium interstitium NN cord-022526-j9kg00qf 3893 30 by by IN cord-022526-j9kg00qf 3893 31 granulomatous granulomatous JJ cord-022526-j9kg00qf 3893 32 infiltration infiltration NN cord-022526-j9kg00qf 3893 33 . . . cord-022526-j9kg00qf 3894 1 Administration administration NN cord-022526-j9kg00qf 3894 2 of of IN cord-022526-j9kg00qf 3894 3 an an DT cord-022526-j9kg00qf 3894 4 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 3894 5 to to IN cord-022526-j9kg00qf 3894 6 horses horse NNS cord-022526-j9kg00qf 3894 7 with with IN cord-022526-j9kg00qf 3894 8 a a DT cord-022526-j9kg00qf 3894 9 heavy heavy JJ cord-022526-j9kg00qf 3894 10 load load NN cord-022526-j9kg00qf 3894 11 of of IN cord-022526-j9kg00qf 3894 12 encysted encysted JJ cord-022526-j9kg00qf 3894 13 larvae larva NNS cord-022526-j9kg00qf 3894 14 also also RB cord-022526-j9kg00qf 3894 15 may may MD cord-022526-j9kg00qf 3894 16 cause cause VB cord-022526-j9kg00qf 3894 17 rapid rapid JJ cord-022526-j9kg00qf 3894 18 larval larval JJ cord-022526-j9kg00qf 3894 19 death death NN cord-022526-j9kg00qf 3894 20 and and CC cord-022526-j9kg00qf 3894 21 acute acute JJ cord-022526-j9kg00qf 3894 22 and and CC cord-022526-j9kg00qf 3894 23 often often RB cord-022526-j9kg00qf 3894 24 severe severe JJ cord-022526-j9kg00qf 3894 25 inflammation inflammation NN cord-022526-j9kg00qf 3894 26 similar similar JJ cord-022526-j9kg00qf 3894 27 to to IN cord-022526-j9kg00qf 3894 28 natural natural JJ cord-022526-j9kg00qf 3894 29 emergence emergence NN cord-022526-j9kg00qf 3894 30 . . . cord-022526-j9kg00qf 3895 1 Cyathostomiasis Cyathostomiasis NNP cord-022526-j9kg00qf 3895 2 may may MD cord-022526-j9kg00qf 3895 3 be be VB cord-022526-j9kg00qf 3895 4 the the DT cord-022526-j9kg00qf 3895 5 most most RBS cord-022526-j9kg00qf 3895 6 commonly commonly RB cord-022526-j9kg00qf 3895 7 identified identify VBN cord-022526-j9kg00qf 3895 8 cause cause NN cord-022526-j9kg00qf 3895 9 of of IN cord-022526-j9kg00qf 3895 10 chronic chronic JJ cord-022526-j9kg00qf 3895 11 diarrhea diarrhea NN cord-022526-j9kg00qf 3895 12 in in IN cord-022526-j9kg00qf 3895 13 the the DT cord-022526-j9kg00qf 3895 14 horse horse NN cord-022526-j9kg00qf 3895 15 . . . cord-022526-j9kg00qf 3896 1 [ [ -LRB- cord-022526-j9kg00qf 3896 2 140 140 CD cord-022526-j9kg00qf 3896 3 ] ] -RRB- cord-022526-j9kg00qf 3896 4 [ [ -LRB- cord-022526-j9kg00qf 3896 5 141 141 CD cord-022526-j9kg00qf 3896 6 ] ] -RRB- cord-022526-j9kg00qf 3896 7 [ [ -LRB- cord-022526-j9kg00qf 3896 8 142 142 CD cord-022526-j9kg00qf 3896 9 ] ] -RRB- cord-022526-j9kg00qf 3897 1 However however RB cord-022526-j9kg00qf 3897 2 , , , cord-022526-j9kg00qf 3897 3 an an DT cord-022526-j9kg00qf 3897 4 acute acute JJ cord-022526-j9kg00qf 3897 5 syndrome syndrome NN cord-022526-j9kg00qf 3897 6 also also RB cord-022526-j9kg00qf 3897 7 has have VBZ cord-022526-j9kg00qf 3897 8 been be VBN cord-022526-j9kg00qf 3897 9 associated associate VBN cord-022526-j9kg00qf 3897 10 with with IN cord-022526-j9kg00qf 3897 11 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3897 12 . . . cord-022526-j9kg00qf 3898 1 138 138 CD cord-022526-j9kg00qf 3898 2 Clinical clinical JJ cord-022526-j9kg00qf 3898 3 signs sign NNS cord-022526-j9kg00qf 3898 4 of of IN cord-022526-j9kg00qf 3898 5 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3898 6 are be VBP cord-022526-j9kg00qf 3898 7 characterized characterize VBN cord-022526-j9kg00qf 3898 8 by by IN cord-022526-j9kg00qf 3898 9 moderate moderate JJ cord-022526-j9kg00qf 3898 10 to to IN cord-022526-j9kg00qf 3898 11 severe severe JJ cord-022526-j9kg00qf 3898 12 weight weight NN cord-022526-j9kg00qf 3898 13 loss loss NN cord-022526-j9kg00qf 3898 14 or or CC cord-022526-j9kg00qf 3898 15 poor poor JJ cord-022526-j9kg00qf 3898 16 weight weight NN cord-022526-j9kg00qf 3898 17 gain gain NN cord-022526-j9kg00qf 3898 18 , , , cord-022526-j9kg00qf 3898 19 ill ill JJ cord-022526-j9kg00qf 3898 20 thrift thrift NN cord-022526-j9kg00qf 3898 21 , , , cord-022526-j9kg00qf 3898 22 ventral ventral JJ cord-022526-j9kg00qf 3898 23 edema edema NN cord-022526-j9kg00qf 3898 24 , , , cord-022526-j9kg00qf 3898 25 intermittent intermittent JJ cord-022526-j9kg00qf 3898 26 fever fever NN cord-022526-j9kg00qf 3898 27 , , , cord-022526-j9kg00qf 3898 28 and and CC cord-022526-j9kg00qf 3898 29 intermittent intermittent JJ cord-022526-j9kg00qf 3898 30 , , , cord-022526-j9kg00qf 3898 31 mild mild JJ cord-022526-j9kg00qf 3898 32 colic colic NN cord-022526-j9kg00qf 3898 33 . . . cord-022526-j9kg00qf 3899 1 Acute acute JJ cord-022526-j9kg00qf 3899 2 onset onset NN cord-022526-j9kg00qf 3899 3 of of IN cord-022526-j9kg00qf 3899 4 diarrhea diarrhea NN cord-022526-j9kg00qf 3899 5 is be VBZ cord-022526-j9kg00qf 3899 6 typically typically RB cord-022526-j9kg00qf 3899 7 profuse profuse JJ cord-022526-j9kg00qf 3899 8 and and CC cord-022526-j9kg00qf 3899 9 progresses progress VBZ cord-022526-j9kg00qf 3899 10 to to IN cord-022526-j9kg00qf 3899 11 chronic chronic JJ cord-022526-j9kg00qf 3899 12 diarrhea diarrhea NN cord-022526-j9kg00qf 3899 13 that that WDT cord-022526-j9kg00qf 3899 14 is be VBZ cord-022526-j9kg00qf 3899 15 often often RB cord-022526-j9kg00qf 3899 16 mild mild JJ cord-022526-j9kg00qf 3899 17 , , , cord-022526-j9kg00qf 3899 18 is be VBZ cord-022526-j9kg00qf 3899 19 the the DT cord-022526-j9kg00qf 3899 20 consistency consistency NN cord-022526-j9kg00qf 3899 21 of of IN cord-022526-j9kg00qf 3899 22 bovine bovine JJ cord-022526-j9kg00qf 3899 23 feces fece NNS cord-022526-j9kg00qf 3899 24 , , , cord-022526-j9kg00qf 3899 25 and and CC cord-022526-j9kg00qf 3899 26 may may MD cord-022526-j9kg00qf 3899 27 be be VB cord-022526-j9kg00qf 3899 28 intermittent intermittent JJ cord-022526-j9kg00qf 3899 29 . . . cord-022526-j9kg00qf 3900 1 [ [ -LRB- cord-022526-j9kg00qf 3900 2 133 133 CD cord-022526-j9kg00qf 3900 3 ] ] -RRB- cord-022526-j9kg00qf 3900 4 [ [ -LRB- cord-022526-j9kg00qf 3900 5 134 134 CD cord-022526-j9kg00qf 3900 6 ] ] -RRB- cord-022526-j9kg00qf 3900 7 [ [ -LRB- cord-022526-j9kg00qf 3900 8 135 135 CD cord-022526-j9kg00qf 3900 9 ] ] -RRB- cord-022526-j9kg00qf 3900 10 [ [ -LRB- cord-022526-j9kg00qf 3900 11 136 136 CD cord-022526-j9kg00qf 3900 12 ] ] -RRB- cord-022526-j9kg00qf 3900 13 [ [ -LRB- cord-022526-j9kg00qf 3900 14 137 137 CD cord-022526-j9kg00qf 3900 15 ] ] -RRB- cord-022526-j9kg00qf 3900 16 [ [ -LRB- cord-022526-j9kg00qf 3900 17 138 138 CD cord-022526-j9kg00qf 3900 18 ] ] -RRB- cord-022526-j9kg00qf 3901 1 142 142 CD cord-022526-j9kg00qf 3901 2 Appetite appetite NN cord-022526-j9kg00qf 3901 3 is be VBZ cord-022526-j9kg00qf 3901 4 usually usually RB cord-022526-j9kg00qf 3901 5 normal normal JJ cord-022526-j9kg00qf 3901 6 , , , cord-022526-j9kg00qf 3901 7 but but CC cord-022526-j9kg00qf 3901 8 affected affect VBN cord-022526-j9kg00qf 3901 9 horses horse NNS cord-022526-j9kg00qf 3901 10 occasionally occasionally RB cord-022526-j9kg00qf 3901 11 have have VBP cord-022526-j9kg00qf 3901 12 a a DT cord-022526-j9kg00qf 3901 13 ravenous ravenous JJ cord-022526-j9kg00qf 3901 14 appetite appetite NN cord-022526-j9kg00qf 3901 15 . . . cord-022526-j9kg00qf 3902 1 Transrectal transrectal JJ cord-022526-j9kg00qf 3902 2 palpation palpation NN cord-022526-j9kg00qf 3902 3 usually usually RB cord-022526-j9kg00qf 3902 4 does do VBZ cord-022526-j9kg00qf 3902 5 not not RB cord-022526-j9kg00qf 3902 6 reveal reveal VB cord-022526-j9kg00qf 3902 7 any any DT cord-022526-j9kg00qf 3902 8 abnormalities abnormality NNS cord-022526-j9kg00qf 3902 9 . . . cord-022526-j9kg00qf 3903 1 Cyathostomiasis Cyathostomiasis NNP cord-022526-j9kg00qf 3903 2 may may MD cord-022526-j9kg00qf 3903 3 affect affect VB cord-022526-j9kg00qf 3903 4 any any DT cord-022526-j9kg00qf 3903 5 age age NN cord-022526-j9kg00qf 3903 6 of of IN cord-022526-j9kg00qf 3903 7 horse horse NN cord-022526-j9kg00qf 3903 8 , , , cord-022526-j9kg00qf 3903 9 and and CC cord-022526-j9kg00qf 3903 10 clinical clinical JJ cord-022526-j9kg00qf 3903 11 signs sign NNS cord-022526-j9kg00qf 3903 12 are be VBP cord-022526-j9kg00qf 3903 13 more more RBR cord-022526-j9kg00qf 3903 14 common common JJ cord-022526-j9kg00qf 3903 15 during during IN cord-022526-j9kg00qf 3903 16 periods period NNS cord-022526-j9kg00qf 3903 17 of of IN cord-022526-j9kg00qf 3903 18 emergence emergence NN cord-022526-j9kg00qf 3903 19 of of IN cord-022526-j9kg00qf 3903 20 larvae larva NNS cord-022526-j9kg00qf 3903 21 , , , cord-022526-j9kg00qf 3903 22 corresponding correspond VBG cord-022526-j9kg00qf 3903 23 to to IN cord-022526-j9kg00qf 3903 24 late late JJ cord-022526-j9kg00qf 3903 25 winter winter NN cord-022526-j9kg00qf 3903 26 and and CC cord-022526-j9kg00qf 3903 27 spring spring NN cord-022526-j9kg00qf 3903 28 in in IN cord-022526-j9kg00qf 3903 29 northern northern JJ cord-022526-j9kg00qf 3903 30 temperate temperate JJ cord-022526-j9kg00qf 3903 31 zones zone NNS cord-022526-j9kg00qf 3903 32 . . . cord-022526-j9kg00qf 3904 1 The the DT cord-022526-j9kg00qf 3904 2 deworming deworme VBG cord-022526-j9kg00qf 3904 3 history history NN cord-022526-j9kg00qf 3904 4 may may MD cord-022526-j9kg00qf 3904 5 appear appear VB cord-022526-j9kg00qf 3904 6 to to TO cord-022526-j9kg00qf 3904 7 be be VB cord-022526-j9kg00qf 3904 8 adequate adequate JJ cord-022526-j9kg00qf 3904 9 . . . cord-022526-j9kg00qf 3905 1 Neutrophilic Neutrophilic NNP cord-022526-j9kg00qf 3905 2 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 3905 3 is be VBZ cord-022526-j9kg00qf 3905 4 typically typically RB cord-022526-j9kg00qf 3905 5 evident evident JJ cord-022526-j9kg00qf 3905 6 , , , cord-022526-j9kg00qf 3905 7 but but CC cord-022526-j9kg00qf 3905 8 the the DT cord-022526-j9kg00qf 3905 9 white white JJ cord-022526-j9kg00qf 3905 10 blood blood NN cord-022526-j9kg00qf 3905 11 cell cell NN cord-022526-j9kg00qf 3905 12 count count NN cord-022526-j9kg00qf 3905 13 may may MD cord-022526-j9kg00qf 3905 14 be be VB cord-022526-j9kg00qf 3905 15 normal normal JJ cord-022526-j9kg00qf 3905 16 . . . cord-022526-j9kg00qf 3906 1 [ [ -LRB- cord-022526-j9kg00qf 3906 2 133 133 CD cord-022526-j9kg00qf 3906 3 ] ] -RRB- cord-022526-j9kg00qf 3906 4 [ [ -LRB- cord-022526-j9kg00qf 3906 5 134 134 CD cord-022526-j9kg00qf 3906 6 ] ] -RRB- cord-022526-j9kg00qf 3906 7 [ [ -LRB- cord-022526-j9kg00qf 3906 8 135 135 CD cord-022526-j9kg00qf 3906 9 ] ] -RRB- cord-022526-j9kg00qf 3906 10 [ [ -LRB- cord-022526-j9kg00qf 3906 11 136 136 CD cord-022526-j9kg00qf 3906 12 ] ] -RRB- cord-022526-j9kg00qf 3906 13 [ [ -LRB- cord-022526-j9kg00qf 3906 14 137 137 CD cord-022526-j9kg00qf 3906 15 ] ] -RRB- cord-022526-j9kg00qf 3907 1 [ [ -LRB- cord-022526-j9kg00qf 3907 2 138 138 CD cord-022526-j9kg00qf 3907 3 ] ] -RRB- cord-022526-j9kg00qf 3908 1 Profound profound JJ cord-022526-j9kg00qf 3908 2 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3908 3 is be VBZ cord-022526-j9kg00qf 3908 4 a a DT cord-022526-j9kg00qf 3908 5 characteristic characteristic JJ cord-022526-j9kg00qf 3908 6 feature feature NN cord-022526-j9kg00qf 3908 7 of of IN cord-022526-j9kg00qf 3908 8 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3908 9 , , , cord-022526-j9kg00qf 3908 10 manifested manifest VBN cord-022526-j9kg00qf 3908 11 clinically clinically RB cord-022526-j9kg00qf 3908 12 by by IN cord-022526-j9kg00qf 3908 13 ventral ventral JJ cord-022526-j9kg00qf 3908 14 edema edema NN cord-022526-j9kg00qf 3908 15 . . . cord-022526-j9kg00qf 3909 1 Plasma plasma NN cord-022526-j9kg00qf 3909 2 αand αand NN cord-022526-j9kg00qf 3910 1 β β NN cord-022526-j9kg00qf 3910 2 - - HYPH cord-022526-j9kg00qf 3910 3 globulin globulin NN cord-022526-j9kg00qf 3910 4 concentrations concentration NNS cord-022526-j9kg00qf 3910 5 may may MD cord-022526-j9kg00qf 3910 6 be be VB cord-022526-j9kg00qf 3910 7 elevated elevate VBN cord-022526-j9kg00qf 3910 8 , , , cord-022526-j9kg00qf 3910 9 which which WDT cord-022526-j9kg00qf 3910 10 can can MD cord-022526-j9kg00qf 3910 11 result result VB cord-022526-j9kg00qf 3910 12 in in IN cord-022526-j9kg00qf 3910 13 a a DT cord-022526-j9kg00qf 3910 14 normal normal JJ cord-022526-j9kg00qf 3910 15 total total JJ cord-022526-j9kg00qf 3910 16 plasma plasma NN cord-022526-j9kg00qf 3910 17 protein protein NN cord-022526-j9kg00qf 3910 18 concentration concentration NN cord-022526-j9kg00qf 3910 19 in in IN cord-022526-j9kg00qf 3910 20 spite spite NN cord-022526-j9kg00qf 3910 21 of of IN cord-022526-j9kg00qf 3910 22 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3910 23 . . . cord-022526-j9kg00qf 3911 1 [ [ -LRB- cord-022526-j9kg00qf 3911 2 134 134 CD cord-022526-j9kg00qf 3911 3 ] ] -RRB- cord-022526-j9kg00qf 3911 4 [ [ -LRB- cord-022526-j9kg00qf 3911 5 135 135 CD cord-022526-j9kg00qf 3911 6 ] ] -RRB- cord-022526-j9kg00qf 3911 7 [ [ -LRB- cord-022526-j9kg00qf 3911 8 136 136 CD cord-022526-j9kg00qf 3911 9 ] ] -RRB- cord-022526-j9kg00qf 3912 1 The the DT cord-022526-j9kg00qf 3912 2 serum serum NN cord-022526-j9kg00qf 3912 3 IgG(T igg(t NN cord-022526-j9kg00qf 3912 4 ) ) -RRB- cord-022526-j9kg00qf 3912 5 concentration concentration NN cord-022526-j9kg00qf 3912 6 , , , cord-022526-j9kg00qf 3912 7 however however RB cord-022526-j9kg00qf 3912 8 , , , cord-022526-j9kg00qf 3912 9 has have VBZ cord-022526-j9kg00qf 3912 10 been be VBN cord-022526-j9kg00qf 3912 11 reported report VBN cord-022526-j9kg00qf 3912 12 to to TO cord-022526-j9kg00qf 3912 13 be be VB cord-022526-j9kg00qf 3912 14 normal normal JJ cord-022526-j9kg00qf 3912 15 , , , cord-022526-j9kg00qf 3912 16 which which WDT cord-022526-j9kg00qf 3912 17 may may MD cord-022526-j9kg00qf 3912 18 help help VB cord-022526-j9kg00qf 3912 19 distinguish distinguish VB cord-022526-j9kg00qf 3912 20 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3912 21 from from IN cord-022526-j9kg00qf 3912 22 S. S. NNP cord-022526-j9kg00qf 3912 23 vulgaris vulgaris NN cord-022526-j9kg00qf 3912 24 infection infection NN cord-022526-j9kg00qf 3912 25 . . . cord-022526-j9kg00qf 3913 1 133 133 CD cord-022526-j9kg00qf 3913 2 , , , cord-022526-j9kg00qf 3913 3 135 135 CD cord-022526-j9kg00qf 3913 4 , , , cord-022526-j9kg00qf 3913 5 136 136 CD cord-022526-j9kg00qf 3914 1 In in IN cord-022526-j9kg00qf 3914 2 addition addition NN cord-022526-j9kg00qf 3914 3 , , , cord-022526-j9kg00qf 3914 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 3914 5 fluid fluid NN cord-022526-j9kg00qf 3914 6 analysis analysis NN cord-022526-j9kg00qf 3914 7 does do VBZ cord-022526-j9kg00qf 3914 8 not not RB cord-022526-j9kg00qf 3914 9 usually usually RB cord-022526-j9kg00qf 3914 10 reveal reveal VB cord-022526-j9kg00qf 3914 11 any any DT cord-022526-j9kg00qf 3914 12 abnormalities abnormality NNS cord-022526-j9kg00qf 3914 13 , , , cord-022526-j9kg00qf 3914 14 in in IN cord-022526-j9kg00qf 3914 15 contrast contrast NN cord-022526-j9kg00qf 3914 16 to to IN cord-022526-j9kg00qf 3914 17 horses horse NNS cord-022526-j9kg00qf 3914 18 with with IN cord-022526-j9kg00qf 3914 19 S. S. NNP cord-022526-j9kg00qf 3914 20 vulgaris vulgaris NN cord-022526-j9kg00qf 3914 21 infection infection NN cord-022526-j9kg00qf 3914 22 . . . cord-022526-j9kg00qf 3915 1 Fecal fecal JJ cord-022526-j9kg00qf 3915 2 analysis analysis NN cord-022526-j9kg00qf 3915 3 may may MD cord-022526-j9kg00qf 3915 4 be be VB cord-022526-j9kg00qf 3915 5 unrewarding unrewarding JJ cord-022526-j9kg00qf 3915 6 because because IN cord-022526-j9kg00qf 3915 7 the the DT cord-022526-j9kg00qf 3915 8 infection infection NN cord-022526-j9kg00qf 3915 9 is be VBZ cord-022526-j9kg00qf 3915 10 often often RB cord-022526-j9kg00qf 3915 11 not not RB cord-022526-j9kg00qf 3915 12 patent patent NN cord-022526-j9kg00qf 3915 13 when when WRB cord-022526-j9kg00qf 3915 14 clinical clinical JJ cord-022526-j9kg00qf 3915 15 signs sign NNS cord-022526-j9kg00qf 3915 16 are be VBP cord-022526-j9kg00qf 3915 17 apparent apparent JJ cord-022526-j9kg00qf 3915 18 . . . cord-022526-j9kg00qf 3916 1 Measurement measurement NN cord-022526-j9kg00qf 3916 2 of of IN cord-022526-j9kg00qf 3916 3 plasma plasma NN cord-022526-j9kg00qf 3916 4 fructosamine fructosamine NN cord-022526-j9kg00qf 3916 5 may may MD cord-022526-j9kg00qf 3916 6 provide provide VB cord-022526-j9kg00qf 3916 7 a a DT cord-022526-j9kg00qf 3916 8 measure measure NN cord-022526-j9kg00qf 3916 9 of of IN cord-022526-j9kg00qf 3916 10 protein protein NN cord-022526-j9kg00qf 3916 11 catabolism catabolism NN cord-022526-j9kg00qf 3916 12 or or CC cord-022526-j9kg00qf 3916 13 protein protein NN cord-022526-j9kg00qf 3916 14 loss loss NN cord-022526-j9kg00qf 3916 15 in in IN cord-022526-j9kg00qf 3916 16 the the DT cord-022526-j9kg00qf 3916 17 absence absence NN cord-022526-j9kg00qf 3916 18 of of IN cord-022526-j9kg00qf 3916 19 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 3916 20 . . . cord-022526-j9kg00qf 3917 1 Plasma plasma NN cord-022526-j9kg00qf 3917 2 fructosamine fructosamine NN cord-022526-j9kg00qf 3917 3 concentrations concentration NNS cord-022526-j9kg00qf 3917 4 are be VBP cord-022526-j9kg00qf 3917 5 significantly significantly RB cord-022526-j9kg00qf 3917 6 lower low JJR cord-022526-j9kg00qf 3917 7 in in IN cord-022526-j9kg00qf 3917 8 horses horse NNS cord-022526-j9kg00qf 3917 9 with with IN cord-022526-j9kg00qf 3917 10 experimental experimental JJ cord-022526-j9kg00qf 3917 11 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3917 12 than than IN cord-022526-j9kg00qf 3917 13 in in IN cord-022526-j9kg00qf 3917 14 normal normal JJ cord-022526-j9kg00qf 3917 15 controls control NNS cord-022526-j9kg00qf 3917 16 , , , cord-022526-j9kg00qf 3917 17 142 142 CD cord-022526-j9kg00qf 3917 18 , , , cord-022526-j9kg00qf 3917 19 143 143 CD cord-022526-j9kg00qf 3917 20 suggesting suggest VBG cord-022526-j9kg00qf 3917 21 that that IN cord-022526-j9kg00qf 3917 22 this this DT cord-022526-j9kg00qf 3917 23 test test NN cord-022526-j9kg00qf 3917 24 may may MD cord-022526-j9kg00qf 3917 25 be be VB cord-022526-j9kg00qf 3917 26 a a DT cord-022526-j9kg00qf 3917 27 useful useful JJ cord-022526-j9kg00qf 3917 28 diagnostic diagnostic JJ cord-022526-j9kg00qf 3917 29 tool tool NN cord-022526-j9kg00qf 3917 30 . . . cord-022526-j9kg00qf 3918 1 However however RB cord-022526-j9kg00qf 3918 2 , , , cord-022526-j9kg00qf 3918 3 the the DT cord-022526-j9kg00qf 3918 4 test test NN cord-022526-j9kg00qf 3918 5 has have VBZ cord-022526-j9kg00qf 3918 6 not not RB cord-022526-j9kg00qf 3918 7 yet yet RB cord-022526-j9kg00qf 3918 8 been be VBN cord-022526-j9kg00qf 3918 9 validated validate VBN cord-022526-j9kg00qf 3918 10 in in IN cord-022526-j9kg00qf 3918 11 naturally naturally RB cord-022526-j9kg00qf 3918 12 occurring occur VBG cord-022526-j9kg00qf 3918 13 cases case NNS cord-022526-j9kg00qf 3918 14 , , , cord-022526-j9kg00qf 3918 15 and and CC cord-022526-j9kg00qf 3918 16 neither neither CC cord-022526-j9kg00qf 3918 17 the the DT cord-022526-j9kg00qf 3918 18 specificity specificity NN cord-022526-j9kg00qf 3918 19 nor nor CC cord-022526-j9kg00qf 3918 20 the the DT cord-022526-j9kg00qf 3918 21 sensitivity sensitivity NN cord-022526-j9kg00qf 3918 22 is be VBZ cord-022526-j9kg00qf 3918 23 known know VBN cord-022526-j9kg00qf 3918 24 . . . cord-022526-j9kg00qf 3919 1 Rectal rectal JJ cord-022526-j9kg00qf 3919 2 scrapings scraping NNS cord-022526-j9kg00qf 3919 3 or or CC cord-022526-j9kg00qf 3919 4 rectal rectal JJ cord-022526-j9kg00qf 3919 5 mucosal mucosal JJ cord-022526-j9kg00qf 3919 6 biopsies biopsy NNS cord-022526-j9kg00qf 3919 7 may may MD cord-022526-j9kg00qf 3919 8 reveal reveal VB cord-022526-j9kg00qf 3919 9 evidence evidence NN cord-022526-j9kg00qf 3919 10 of of IN cord-022526-j9kg00qf 3919 11 cyathostome cyathostome NN cord-022526-j9kg00qf 3919 12 larvae larva NNS cord-022526-j9kg00qf 3919 13 . . . cord-022526-j9kg00qf 3920 1 133 133 CD cord-022526-j9kg00qf 3920 2 , , , cord-022526-j9kg00qf 3920 3 136 136 CD cord-022526-j9kg00qf 3920 4 Definitive definitive JJ cord-022526-j9kg00qf 3920 5 diagnosis diagnosis NN cord-022526-j9kg00qf 3920 6 usually usually RB cord-022526-j9kg00qf 3920 7 requires require VBZ cord-022526-j9kg00qf 3920 8 microscopic microscopic JJ cord-022526-j9kg00qf 3920 9 examination examination NN cord-022526-j9kg00qf 3920 10 of of IN cord-022526-j9kg00qf 3920 11 biopsy biopsy NN cord-022526-j9kg00qf 3920 12 specimens specimen NNS cord-022526-j9kg00qf 3920 13 of of IN cord-022526-j9kg00qf 3920 14 the the DT cord-022526-j9kg00qf 3920 15 cecum cecum NN cord-022526-j9kg00qf 3920 16 and and CC cord-022526-j9kg00qf 3920 17 ascending ascend VBG cord-022526-j9kg00qf 3920 18 colon colon NN cord-022526-j9kg00qf 3920 19 , , , cord-022526-j9kg00qf 3920 20 collected collect VBN cord-022526-j9kg00qf 3920 21 by by IN cord-022526-j9kg00qf 3920 22 laparotomy laparotomy NN cord-022526-j9kg00qf 3920 23 . . . cord-022526-j9kg00qf 3921 1 Examination examination NN cord-022526-j9kg00qf 3921 2 of of IN cord-022526-j9kg00qf 3921 3 biopsy biopsy NN cord-022526-j9kg00qf 3921 4 specimens specimen NNS cord-022526-j9kg00qf 3921 5 collected collect VBN cord-022526-j9kg00qf 3921 6 from from IN cord-022526-j9kg00qf 3921 7 the the DT cord-022526-j9kg00qf 3921 8 small small JJ cord-022526-j9kg00qf 3921 9 intestine intestine NN cord-022526-j9kg00qf 3921 10 is be VBZ cord-022526-j9kg00qf 3921 11 recommended recommend VBN cord-022526-j9kg00qf 3921 12 to to TO cord-022526-j9kg00qf 3921 13 rule rule VB cord-022526-j9kg00qf 3921 14 out out RP cord-022526-j9kg00qf 3921 15 other other JJ cord-022526-j9kg00qf 3921 16 causes cause NNS cord-022526-j9kg00qf 3921 17 of of IN cord-022526-j9kg00qf 3921 18 weight weight NN cord-022526-j9kg00qf 3921 19 loss loss NN cord-022526-j9kg00qf 3921 20 and and CC cord-022526-j9kg00qf 3921 21 diarrhea diarrhea NN cord-022526-j9kg00qf 3921 22 . . . cord-022526-j9kg00qf 3922 1 One one PRP cord-022526-j9kg00qf 3922 2 should should MD cord-022526-j9kg00qf 3922 3 include include VB cord-022526-j9kg00qf 3922 4 appropriate appropriate JJ cord-022526-j9kg00qf 3922 5 diagnostic diagnostic JJ cord-022526-j9kg00qf 3922 6 tests test NNS cord-022526-j9kg00qf 3922 7 , , , cord-022526-j9kg00qf 3922 8 such such JJ cord-022526-j9kg00qf 3922 9 as as IN cord-022526-j9kg00qf 3922 10 culture culture NN cord-022526-j9kg00qf 3922 11 of of IN cord-022526-j9kg00qf 3922 12 feces fece NNS cord-022526-j9kg00qf 3922 13 for for IN cord-022526-j9kg00qf 3922 14 pathogenic pathogenic JJ cord-022526-j9kg00qf 3922 15 bacteria bacteria NNS cord-022526-j9kg00qf 3922 16 , , , cord-022526-j9kg00qf 3922 17 in in IN cord-022526-j9kg00qf 3922 18 the the DT cord-022526-j9kg00qf 3922 19 workup workup NN cord-022526-j9kg00qf 3922 20 to to TO cord-022526-j9kg00qf 3922 21 rule rule VB cord-022526-j9kg00qf 3922 22 out out RP cord-022526-j9kg00qf 3922 23 other other JJ cord-022526-j9kg00qf 3922 24 causes cause NNS cord-022526-j9kg00qf 3922 25 . . . cord-022526-j9kg00qf 3923 1 Preventive preventive JJ cord-022526-j9kg00qf 3923 2 measures measure NNS cord-022526-j9kg00qf 3923 3 are be VBP cord-022526-j9kg00qf 3923 4 appropriate appropriate JJ cord-022526-j9kg00qf 3923 5 for for IN cord-022526-j9kg00qf 3923 6 other other JJ cord-022526-j9kg00qf 3923 7 horses horse NNS cord-022526-j9kg00qf 3923 8 on on IN cord-022526-j9kg00qf 3923 9 premises premise NNS cord-022526-j9kg00qf 3923 10 known know VBN cord-022526-j9kg00qf 3923 11 to to TO cord-022526-j9kg00qf 3923 12 have have VB cord-022526-j9kg00qf 3923 13 a a DT cord-022526-j9kg00qf 3923 14 problem problem NN cord-022526-j9kg00qf 3923 15 with with IN cord-022526-j9kg00qf 3923 16 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 3923 17 , , , cord-022526-j9kg00qf 3923 18 particularly particularly RB cord-022526-j9kg00qf 3923 19 frequent frequent JJ cord-022526-j9kg00qf 3923 20 deworming deworming NN cord-022526-j9kg00qf 3923 21 ( ( -LRB- cord-022526-j9kg00qf 3923 22 every every DT cord-022526-j9kg00qf 3923 23 6 6 CD cord-022526-j9kg00qf 3923 24 weeks week NNS cord-022526-j9kg00qf 3923 25 ) ) -RRB- cord-022526-j9kg00qf 3923 26 during during IN cord-022526-j9kg00qf 3923 27 times time NNS cord-022526-j9kg00qf 3923 28 of of IN cord-022526-j9kg00qf 3923 29 high high JJ cord-022526-j9kg00qf 3923 30 infectivity infectivity NN cord-022526-j9kg00qf 3923 31 ( ( -LRB- cord-022526-j9kg00qf 3923 32 spring spring NN cord-022526-j9kg00qf 3923 33 and and CC cord-022526-j9kg00qf 3923 34 summer summer NN cord-022526-j9kg00qf 3923 35 in in IN cord-022526-j9kg00qf 3923 36 the the DT cord-022526-j9kg00qf 3923 37 north north NN cord-022526-j9kg00qf 3923 38 and and CC cord-022526-j9kg00qf 3923 39 fall fall VB cord-022526-j9kg00qf 3923 40 , , , cord-022526-j9kg00qf 3923 41 winter winter NN cord-022526-j9kg00qf 3923 42 , , , cord-022526-j9kg00qf 3923 43 and and CC cord-022526-j9kg00qf 3923 44 early early JJ cord-022526-j9kg00qf 3923 45 spring spring NN cord-022526-j9kg00qf 3923 46 in in IN cord-022526-j9kg00qf 3923 47 the the DT cord-022526-j9kg00qf 3923 48 south south NN cord-022526-j9kg00qf 3923 49 ) ) -RRB- cord-022526-j9kg00qf 3923 50 to to TO cord-022526-j9kg00qf 3923 51 eliminate eliminate VB cord-022526-j9kg00qf 3923 52 parasites parasite NNS cord-022526-j9kg00qf 3923 53 before before IN cord-022526-j9kg00qf 3923 54 they -PRON- PRP cord-022526-j9kg00qf 3923 55 become become VBP cord-022526-j9kg00qf 3923 56 patent patent NN cord-022526-j9kg00qf 3923 57 . . . cord-022526-j9kg00qf 3924 1 133 133 CD cord-022526-j9kg00qf 3925 1 Because because IN cord-022526-j9kg00qf 3925 2 of of IN cord-022526-j9kg00qf 3925 3 high high JJ cord-022526-j9kg00qf 3925 4 levels level NNS cord-022526-j9kg00qf 3925 5 of of IN cord-022526-j9kg00qf 3925 6 resistance resistance NN cord-022526-j9kg00qf 3925 7 to to IN cord-022526-j9kg00qf 3925 8 benzimidazoles benzimidazoles NNP cord-022526-j9kg00qf 3925 9 , , , cord-022526-j9kg00qf 3925 10 avermectins avermectins NNP cord-022526-j9kg00qf 3925 11 ( ( -LRB- cord-022526-j9kg00qf 3925 12 ivermectin ivermectin NNP cord-022526-j9kg00qf 3925 13 or or CC cord-022526-j9kg00qf 3925 14 moxidectin moxidectin NNP cord-022526-j9kg00qf 3925 15 ) ) -RRB- cord-022526-j9kg00qf 3925 16 are be VBP cord-022526-j9kg00qf 3925 17 the the DT cord-022526-j9kg00qf 3925 18 drugs drug NNS cord-022526-j9kg00qf 3925 19 of of IN cord-022526-j9kg00qf 3925 20 choice choice NN cord-022526-j9kg00qf 3925 21 . . . cord-022526-j9kg00qf 3926 1 [ [ -LRB- cord-022526-j9kg00qf 3926 2 144 144 CD cord-022526-j9kg00qf 3926 3 ] ] -RRB- cord-022526-j9kg00qf 3926 4 [ [ -LRB- cord-022526-j9kg00qf 3926 5 145 145 CD cord-022526-j9kg00qf 3926 6 ] ] -RRB- cord-022526-j9kg00qf 3927 1 [ [ -LRB- cord-022526-j9kg00qf 3927 2 146 146 CD cord-022526-j9kg00qf 3927 3 ] ] -RRB- cord-022526-j9kg00qf 3927 4 Resistance Resistance NNP cord-022526-j9kg00qf 3927 5 to to IN cord-022526-j9kg00qf 3927 6 ivermectin ivermectin NNP cord-022526-j9kg00qf 3927 7 has have VBZ cord-022526-j9kg00qf 3927 8 been be VBN cord-022526-j9kg00qf 3927 9 demonstrated demonstrate VBN cord-022526-j9kg00qf 3927 10 , , , cord-022526-j9kg00qf 3927 11 but but CC cord-022526-j9kg00qf 3927 12 the the DT cord-022526-j9kg00qf 3927 13 prevalence prevalence NN cord-022526-j9kg00qf 3927 14 of of IN cord-022526-j9kg00qf 3927 15 ivermectin ivermectin NNP cord-022526-j9kg00qf 3927 16 resistance resistance NN cord-022526-j9kg00qf 3927 17 appears appear VBZ cord-022526-j9kg00qf 3927 18 to to TO cord-022526-j9kg00qf 3927 19 remain remain VB cord-022526-j9kg00qf 3927 20 low low JJ cord-022526-j9kg00qf 3927 21 . . . cord-022526-j9kg00qf 3927 22 144 144 CD cord-022526-j9kg00qf 3928 1 Although although IN cord-022526-j9kg00qf 3928 2 daily daily JJ cord-022526-j9kg00qf 3928 3 pyrantel pyrantel NNP cord-022526-j9kg00qf 3928 4 pamoate pamoate NNP cord-022526-j9kg00qf 3928 5 administration administration NNP cord-022526-j9kg00qf 3928 6 also also RB cord-022526-j9kg00qf 3928 7 has have VBZ cord-022526-j9kg00qf 3928 8 been be VBN cord-022526-j9kg00qf 3928 9 reported report VBN cord-022526-j9kg00qf 3928 10 to to TO cord-022526-j9kg00qf 3928 11 reduce reduce VB cord-022526-j9kg00qf 3928 12 worm worm NN cord-022526-j9kg00qf 3928 13 burdens burden NNS cord-022526-j9kg00qf 3928 14 and and CC cord-022526-j9kg00qf 3928 15 pasture pasture NN cord-022526-j9kg00qf 3928 16 infectivity infectivity NN cord-022526-j9kg00qf 3928 17 in in IN cord-022526-j9kg00qf 3928 18 young young JJ cord-022526-j9kg00qf 3928 19 and and CC cord-022526-j9kg00qf 3928 20 mature mature JJ cord-022526-j9kg00qf 3928 21 horses horse NNS cord-022526-j9kg00qf 3928 22 effectively effectively RB cord-022526-j9kg00qf 3928 23 , , , cord-022526-j9kg00qf 3928 24 147 147 CD cord-022526-j9kg00qf 3928 25 cyathostome cyathostome NN cord-022526-j9kg00qf 3928 26 resistance resistance NN cord-022526-j9kg00qf 3928 27 has have VBZ cord-022526-j9kg00qf 3928 28 been be VBN cord-022526-j9kg00qf 3928 29 reported report VBN cord-022526-j9kg00qf 3928 30 and and CC cord-022526-j9kg00qf 3928 31 is be VBZ cord-022526-j9kg00qf 3928 32 a a DT cord-022526-j9kg00qf 3928 33 concern concern NN cord-022526-j9kg00qf 3928 34 for for IN cord-022526-j9kg00qf 3928 35 the the DT cord-022526-j9kg00qf 3928 36 use use NN cord-022526-j9kg00qf 3928 37 of of IN cord-022526-j9kg00qf 3928 38 this this DT cord-022526-j9kg00qf 3928 39 drug drug NN cord-022526-j9kg00qf 3928 40 as as IN cord-022526-j9kg00qf 3928 41 a a DT cord-022526-j9kg00qf 3928 42 routine routine JJ cord-022526-j9kg00qf 3928 43 preventive preventive JJ cord-022526-j9kg00qf 3928 44 anthelmintic anthelmintic NN cord-022526-j9kg00qf 3928 45 . . . cord-022526-j9kg00qf 3929 1 145 145 CD cord-022526-j9kg00qf 3929 2 , , , cord-022526-j9kg00qf 3929 3 148 148 CD cord-022526-j9kg00qf 3929 4 _SP cord-022526-j9kg00qf 3929 5 Diarrhea diarrhea NN cord-022526-j9kg00qf 3929 6 in in IN cord-022526-j9kg00qf 3929 7 adult adult NN cord-022526-j9kg00qf 3929 8 horses horse NNS cord-022526-j9kg00qf 3929 9 may may MD cord-022526-j9kg00qf 3929 10 also also RB cord-022526-j9kg00qf 3929 11 occur occur VB cord-022526-j9kg00qf 3929 12 secondary secondary JJ cord-022526-j9kg00qf 3929 13 to to IN cord-022526-j9kg00qf 3929 14 administration administration NN cord-022526-j9kg00qf 3929 15 of of IN cord-022526-j9kg00qf 3929 16 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 3929 17 or or CC cord-022526-j9kg00qf 3929 18 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3929 19 medications medication NNS cord-022526-j9kg00qf 3929 20 or or CC cord-022526-j9kg00qf 3929 21 after after IN cord-022526-j9kg00qf 3929 22 ingestion ingestion NN cord-022526-j9kg00qf 3929 23 of of IN cord-022526-j9kg00qf 3929 24 toxic toxic JJ cord-022526-j9kg00qf 3929 25 compounds compound NNS cord-022526-j9kg00qf 3929 26 . . . cord-022526-j9kg00qf 3930 1 Affected affected JJ cord-022526-j9kg00qf 3930 2 horses horse NNS cord-022526-j9kg00qf 3930 3 exhibit exhibit VBP cord-022526-j9kg00qf 3930 4 clinical clinical JJ cord-022526-j9kg00qf 3930 5 signs sign NNS cord-022526-j9kg00qf 3930 6 that that WDT cord-022526-j9kg00qf 3930 7 may may MD cord-022526-j9kg00qf 3930 8 be be VB cord-022526-j9kg00qf 3930 9 indistinguishable indistinguishable JJ cord-022526-j9kg00qf 3930 10 from from IN cord-022526-j9kg00qf 3930 11 signs sign NNS cord-022526-j9kg00qf 3930 12 exhibited exhibit VBN cord-022526-j9kg00qf 3930 13 by by IN cord-022526-j9kg00qf 3930 14 horses horse NNS cord-022526-j9kg00qf 3930 15 with with IN cord-022526-j9kg00qf 3930 16 diarrhea diarrhea NN cord-022526-j9kg00qf 3930 17 of of IN cord-022526-j9kg00qf 3930 18 infectious infectious JJ cord-022526-j9kg00qf 3930 19 etiology etiology NN cord-022526-j9kg00qf 3930 20 . . . cord-022526-j9kg00qf 3931 1 Antibiotic antibiotic NN cord-022526-j9kg00qf 3931 2 - - HYPH cord-022526-j9kg00qf 3931 3 associated associate VBN cord-022526-j9kg00qf 3931 4 diarrhea diarrhea NN cord-022526-j9kg00qf 3931 5 has have VBZ cord-022526-j9kg00qf 3931 6 been be VBN cord-022526-j9kg00qf 3931 7 reported report VBN cord-022526-j9kg00qf 3931 8 in in IN cord-022526-j9kg00qf 3931 9 many many JJ cord-022526-j9kg00qf 3931 10 species specie NNS cord-022526-j9kg00qf 3931 11 , , , cord-022526-j9kg00qf 3931 12 including include VBG cord-022526-j9kg00qf 3931 13 horses horse NNS cord-022526-j9kg00qf 3931 14 . . . cord-022526-j9kg00qf 3932 1 149 149 CD cord-022526-j9kg00qf 3933 1 Certain certain JJ cord-022526-j9kg00qf 3933 2 antibiotics antibiotic NNS cord-022526-j9kg00qf 3933 3 - - : cord-022526-j9kg00qf 3933 4 such such JJ cord-022526-j9kg00qf 3933 5 as as IN cord-022526-j9kg00qf 3933 6 trimethoprim trimethoprim NN cord-022526-j9kg00qf 3933 7 - - HYPH cord-022526-j9kg00qf 3933 8 sulfonamide sulfonamide NN cord-022526-j9kg00qf 3933 9 combinations combination NNS cord-022526-j9kg00qf 3933 10 , , , cord-022526-j9kg00qf 3933 11 erythromycin erythromycin NN cord-022526-j9kg00qf 3933 12 , , , cord-022526-j9kg00qf 3933 13 penicillins penicillin NNS cord-022526-j9kg00qf 3933 14 , , , cord-022526-j9kg00qf 3933 15 tetracyclines tetracycline NNS cord-022526-j9kg00qf 3933 16 , , , cord-022526-j9kg00qf 3933 17 clindamycin clindamycin NN cord-022526-j9kg00qf 3933 18 , , , cord-022526-j9kg00qf 3933 19 and and CC cord-022526-j9kg00qf 3933 20 lincomycinare lincomycinare NNP cord-022526-j9kg00qf 3934 1 associated associate VBN cord-022526-j9kg00qf 3934 2 with with IN cord-022526-j9kg00qf 3934 3 naturally naturally RB cord-022526-j9kg00qf 3934 4 occurring occur VBG cord-022526-j9kg00qf 3934 5 and and CC cord-022526-j9kg00qf 3934 6 experimental experimental JJ cord-022526-j9kg00qf 3934 7 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3934 8 syndromes syndrome NNS cord-022526-j9kg00qf 3934 9 in in IN cord-022526-j9kg00qf 3934 10 horses horse NNS cord-022526-j9kg00qf 3934 11 . . . cord-022526-j9kg00qf 3935 1 79 79 CD cord-022526-j9kg00qf 3935 2 , , , cord-022526-j9kg00qf 3935 3 [ [ -LRB- cord-022526-j9kg00qf 3935 4 149 149 CD cord-022526-j9kg00qf 3935 5 ] ] -RRB- cord-022526-j9kg00qf 3935 6 [ [ -LRB- cord-022526-j9kg00qf 3935 7 150 150 CD cord-022526-j9kg00qf 3935 8 ] ] -RRB- cord-022526-j9kg00qf 3935 9 [ [ -LRB- cord-022526-j9kg00qf 3935 10 151 151 CD cord-022526-j9kg00qf 3935 11 ] ] -RRB- cord-022526-j9kg00qf 3935 12 [ [ -LRB- cord-022526-j9kg00qf 3935 13 152 152 CD cord-022526-j9kg00qf 3935 14 ] ] -RRB- cord-022526-j9kg00qf 3936 1 In in IN cord-022526-j9kg00qf 3936 2 some some DT cord-022526-j9kg00qf 3936 3 cases case NNS cord-022526-j9kg00qf 3936 4 , , , cord-022526-j9kg00qf 3936 5 such such JJ cord-022526-j9kg00qf 3936 6 as as IN cord-022526-j9kg00qf 3936 7 with with IN cord-022526-j9kg00qf 3936 8 trimethoprim trimethoprim NN cord-022526-j9kg00qf 3936 9 - - HYPH cord-022526-j9kg00qf 3936 10 sulfonamide sulfonamide NN cord-022526-j9kg00qf 3936 11 combinations combination NNS cord-022526-j9kg00qf 3936 12 , , , cord-022526-j9kg00qf 3936 13 the the DT cord-022526-j9kg00qf 3936 14 geographic geographic JJ cord-022526-j9kg00qf 3936 15 incidence incidence NN cord-022526-j9kg00qf 3936 16 of of IN cord-022526-j9kg00qf 3936 17 antibiotic antibiotic JJ cord-022526-j9kg00qf 3936 18 - - HYPH cord-022526-j9kg00qf 3936 19 associated associated JJ cord-022526-j9kg00qf 3936 20 diarrhea diarrhea NN cord-022526-j9kg00qf 3936 21 appears appear VBZ cord-022526-j9kg00qf 3936 22 to to TO cord-022526-j9kg00qf 3936 23 differ differ VB cord-022526-j9kg00qf 3936 24 considerably considerably RB cord-022526-j9kg00qf 3936 25 . . . cord-022526-j9kg00qf 3937 1 Clostridium clostridium NN cord-022526-j9kg00qf 3937 2 perfringens perfringen NNS cord-022526-j9kg00qf 3937 3 , , , cord-022526-j9kg00qf 3937 4 C. C. NNP cord-022526-j9kg00qf 3937 5 difficile difficile NN cord-022526-j9kg00qf 3937 6 , , , cord-022526-j9kg00qf 3937 7 and and CC cord-022526-j9kg00qf 3937 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 3937 9 spp spp NNS cord-022526-j9kg00qf 3937 10 . . . cord-022526-j9kg00qf 3938 1 are be VBP cord-022526-j9kg00qf 3938 2 apparently apparently RB cord-022526-j9kg00qf 3938 3 the the DT cord-022526-j9kg00qf 3938 4 most most RBS cord-022526-j9kg00qf 3938 5 common common JJ cord-022526-j9kg00qf 3938 6 causes cause NNS cord-022526-j9kg00qf 3938 7 of of IN cord-022526-j9kg00qf 3938 8 antibioticassociated antibioticassociated JJ cord-022526-j9kg00qf 3938 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3938 10 in in IN cord-022526-j9kg00qf 3938 11 horses horse NNS cord-022526-j9kg00qf 3938 12 . . . cord-022526-j9kg00qf 3939 1 Outbreaks outbreak NNS cord-022526-j9kg00qf 3939 2 of of IN cord-022526-j9kg00qf 3939 3 C. C. NNP cord-022526-j9kg00qf 3939 4 difficile difficile NN cord-022526-j9kg00qf 3939 5 have have VBP cord-022526-j9kg00qf 3939 6 been be VBN cord-022526-j9kg00qf 3939 7 reported report VBN cord-022526-j9kg00qf 3939 8 in in IN cord-022526-j9kg00qf 3939 9 hospitalized hospitalize VBN cord-022526-j9kg00qf 3939 10 horses horse NNS cord-022526-j9kg00qf 3939 11 being be VBG cord-022526-j9kg00qf 3939 12 treated treat VBN cord-022526-j9kg00qf 3939 13 with with IN cord-022526-j9kg00qf 3939 14 antibiotics antibiotic NNS cord-022526-j9kg00qf 3939 15 . . . cord-022526-j9kg00qf 3940 1 81 81 CD cord-022526-j9kg00qf 3940 2 , , , cord-022526-j9kg00qf 3940 3 85 85 CD cord-022526-j9kg00qf 3941 1 In in IN cord-022526-j9kg00qf 3941 2 Sweden Sweden NNP cord-022526-j9kg00qf 3941 3 , , , cord-022526-j9kg00qf 3941 4 accidental accidental JJ cord-022526-j9kg00qf 3941 5 erythromycin erythromycin JJ cord-022526-j9kg00qf 3941 6 ingestion ingestion NN cord-022526-j9kg00qf 3941 7 has have VBZ cord-022526-j9kg00qf 3941 8 been be VBN cord-022526-j9kg00qf 3941 9 associated associate VBN cord-022526-j9kg00qf 3941 10 with with IN cord-022526-j9kg00qf 3941 11 C. C. NNP cord-022526-j9kg00qf 3941 12 difficile difficile NN cord-022526-j9kg00qf 3941 13 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3941 14 in in IN cord-022526-j9kg00qf 3941 15 mares mare NNS cord-022526-j9kg00qf 3941 16 in in IN cord-022526-j9kg00qf 3941 17 which which WDT cord-022526-j9kg00qf 3941 18 their -PRON- PRP$ cord-022526-j9kg00qf 3941 19 foals foal NNS cord-022526-j9kg00qf 3941 20 were be VBD cord-022526-j9kg00qf 3941 21 being be VBG cord-022526-j9kg00qf 3941 22 treated treat VBN cord-022526-j9kg00qf 3941 23 for for IN cord-022526-j9kg00qf 3941 24 Rhodococcus Rhodococcus NNP cord-022526-j9kg00qf 3941 25 equi equi NN cord-022526-j9kg00qf 3941 26 . . . cord-022526-j9kg00qf 3942 1 89 89 CD cord-022526-j9kg00qf 3942 2 , , , cord-022526-j9kg00qf 3942 3 151 151 CD cord-022526-j9kg00qf 3942 4 , , , cord-022526-j9kg00qf 3942 5 153 153 CD cord-022526-j9kg00qf 3943 1 Interestingly interestingly RB cord-022526-j9kg00qf 3943 2 , , , cord-022526-j9kg00qf 3943 3 this this DT cord-022526-j9kg00qf 3943 4 phenomenon phenomenon NN cord-022526-j9kg00qf 3943 5 has have VBZ cord-022526-j9kg00qf 3943 6 not not RB cord-022526-j9kg00qf 3943 7 been be VBN cord-022526-j9kg00qf 3943 8 reported report VBN cord-022526-j9kg00qf 3943 9 in in IN cord-022526-j9kg00qf 3943 10 other other JJ cord-022526-j9kg00qf 3943 11 areas area NNS cord-022526-j9kg00qf 3943 12 of of IN cord-022526-j9kg00qf 3943 13 the the DT cord-022526-j9kg00qf 3943 14 world world NN cord-022526-j9kg00qf 3943 15 . . . cord-022526-j9kg00qf 3944 1 Foals foal NNS cord-022526-j9kg00qf 3944 2 being be VBG cord-022526-j9kg00qf 3944 3 treated treat VBN cord-022526-j9kg00qf 3944 4 with with IN cord-022526-j9kg00qf 3944 5 erythromycin erythromycin NNS cord-022526-j9kg00qf 3944 6 are be VBP cord-022526-j9kg00qf 3944 7 at at IN cord-022526-j9kg00qf 3944 8 a a DT cord-022526-j9kg00qf 3944 9 higher high JJR cord-022526-j9kg00qf 3944 10 risk risk NN cord-022526-j9kg00qf 3944 11 for for IN cord-022526-j9kg00qf 3944 12 diarrhea diarrhea NN cord-022526-j9kg00qf 3944 13 than than IN cord-022526-j9kg00qf 3944 14 foals foal NNS cord-022526-j9kg00qf 3944 15 being be VBG cord-022526-j9kg00qf 3944 16 treated treat VBN cord-022526-j9kg00qf 3944 17 with with IN cord-022526-j9kg00qf 3944 18 other other JJ cord-022526-j9kg00qf 3944 19 antibiotics antibiotic NNS cord-022526-j9kg00qf 3944 20 . . . cord-022526-j9kg00qf 3945 1 Tetracycline Tetracycline NNP cord-022526-j9kg00qf 3945 2 administration administration NN cord-022526-j9kg00qf 3945 3 has have VBZ cord-022526-j9kg00qf 3945 4 been be VBN cord-022526-j9kg00qf 3945 5 shown show VBN cord-022526-j9kg00qf 3945 6 to to TO cord-022526-j9kg00qf 3945 7 be be VB cord-022526-j9kg00qf 3945 8 associated associate VBN cord-022526-j9kg00qf 3945 9 with with IN cord-022526-j9kg00qf 3945 10 an an DT cord-022526-j9kg00qf 3945 11 increase increase NN cord-022526-j9kg00qf 3945 12 in in IN cord-022526-j9kg00qf 3945 13 the the DT cord-022526-j9kg00qf 3945 14 numbers number NNS cord-022526-j9kg00qf 3945 15 of of IN cord-022526-j9kg00qf 3945 16 gram gram NN cord-022526-j9kg00qf 3945 17 - - HYPH cord-022526-j9kg00qf 3945 18 negative negative JJ cord-022526-j9kg00qf 3945 19 enteric enteric JJ cord-022526-j9kg00qf 3945 20 bacteria bacteria NNS cord-022526-j9kg00qf 3945 21 and and CC cord-022526-j9kg00qf 3945 22 C. C. NNP cord-022526-j9kg00qf 3945 23 perfringens perfringen NNS cord-022526-j9kg00qf 3945 24 in in IN cord-022526-j9kg00qf 3945 25 the the DT cord-022526-j9kg00qf 3945 26 feces fece NNS cord-022526-j9kg00qf 3945 27 of of IN cord-022526-j9kg00qf 3945 28 horses horse NNS cord-022526-j9kg00qf 3945 29 and and CC cord-022526-j9kg00qf 3945 30 reactivation reactivation NN cord-022526-j9kg00qf 3945 31 of of IN cord-022526-j9kg00qf 3945 32 salmonellosis salmonellosis NN cord-022526-j9kg00qf 3945 33 and and CC cord-022526-j9kg00qf 3945 34 prolongation prolongation NN cord-022526-j9kg00qf 3945 35 of of IN cord-022526-j9kg00qf 3945 36 fecal fecal JJ cord-022526-j9kg00qf 3945 37 shedding shedding NN cord-022526-j9kg00qf 3945 38 of of IN cord-022526-j9kg00qf 3945 39 Salmonella Salmonella NNP cord-022526-j9kg00qf 3945 40 . . . cord-022526-j9kg00qf 3946 1 78 78 CD cord-022526-j9kg00qf 3946 2 , , , cord-022526-j9kg00qf 3946 3 154 154 CD cord-022526-j9kg00qf 3947 1 The the DT cord-022526-j9kg00qf 3947 2 most most RBS cord-022526-j9kg00qf 3947 3 common common JJ cord-022526-j9kg00qf 3947 4 mechanism mechanism NN cord-022526-j9kg00qf 3947 5 by by IN cord-022526-j9kg00qf 3947 6 which which WDT cord-022526-j9kg00qf 3947 7 antibiotics antibiotic NNS cord-022526-j9kg00qf 3947 8 cause cause VBP cord-022526-j9kg00qf 3947 9 diarrhea diarrhea NN cord-022526-j9kg00qf 3947 10 is be VBZ cord-022526-j9kg00qf 3947 11 by by IN cord-022526-j9kg00qf 3947 12 disrupting disrupt VBG cord-022526-j9kg00qf 3947 13 the the DT cord-022526-j9kg00qf 3947 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3947 15 flora flora NNS cord-022526-j9kg00qf 3947 16 . . . cord-022526-j9kg00qf 3948 1 The the DT cord-022526-j9kg00qf 3948 2 normal normal JJ cord-022526-j9kg00qf 3948 3 large large JJ cord-022526-j9kg00qf 3948 4 intestinal intestinal JJ cord-022526-j9kg00qf 3948 5 flora flora NNS cord-022526-j9kg00qf 3948 6 , , , cord-022526-j9kg00qf 3948 7 comprised comprise VBN cord-022526-j9kg00qf 3948 8 of of IN cord-022526-j9kg00qf 3948 9 mainly mainly RB cord-022526-j9kg00qf 3948 10 obligate obligate VBP cord-022526-j9kg00qf 3948 11 anaerobes anaerobe NNS cord-022526-j9kg00qf 3948 12 and and CC cord-022526-j9kg00qf 3948 13 streptococci streptococcus NNS cord-022526-j9kg00qf 3948 14 , , , cord-022526-j9kg00qf 3948 15 protects protect VBZ cord-022526-j9kg00qf 3948 16 the the DT cord-022526-j9kg00qf 3948 17 host host NN cord-022526-j9kg00qf 3948 18 from from IN cord-022526-j9kg00qf 3948 19 pathogenic pathogenic JJ cord-022526-j9kg00qf 3948 20 bacteria bacteria NNS cord-022526-j9kg00qf 3948 21 by by IN cord-022526-j9kg00qf 3948 22 colonization colonization NN cord-022526-j9kg00qf 3948 23 resistance resistance NN cord-022526-j9kg00qf 3948 24 . . . cord-022526-j9kg00qf 3949 1 17 17 CD cord-022526-j9kg00qf 3949 2 Ecologic Ecologic NNP cord-022526-j9kg00qf 3949 3 factors factor NNS cord-022526-j9kg00qf 3949 4 play play VBP cord-022526-j9kg00qf 3949 5 an an DT cord-022526-j9kg00qf 3949 6 important important JJ cord-022526-j9kg00qf 3949 7 role role NN cord-022526-j9kg00qf 3949 8 in in IN cord-022526-j9kg00qf 3949 9 colonization colonization NN cord-022526-j9kg00qf 3949 10 resistance resistance NN cord-022526-j9kg00qf 3949 11 . . . cord-022526-j9kg00qf 3950 1 For for IN cord-022526-j9kg00qf 3950 2 example example NN cord-022526-j9kg00qf 3950 3 , , , cord-022526-j9kg00qf 3950 4 surface surface NN cord-022526-j9kg00qf 3950 5 bacteria bacteria NNS cord-022526-j9kg00qf 3950 6 in in IN cord-022526-j9kg00qf 3950 7 the the DT cord-022526-j9kg00qf 3950 8 large large JJ cord-022526-j9kg00qf 3950 9 intestine intestine NN cord-022526-j9kg00qf 3950 10 interact interact VBP cord-022526-j9kg00qf 3950 11 with with IN cord-022526-j9kg00qf 3950 12 receptors receptor NNS cord-022526-j9kg00qf 3950 13 on on IN cord-022526-j9kg00qf 3950 14 the the DT cord-022526-j9kg00qf 3950 15 mucosal mucosal JJ cord-022526-j9kg00qf 3950 16 cells cell NNS cord-022526-j9kg00qf 3950 17 , , , cord-022526-j9kg00qf 3950 18 facilitating facilitate VBG cord-022526-j9kg00qf 3950 19 adherence adherence NN cord-022526-j9kg00qf 3950 20 to to IN cord-022526-j9kg00qf 3950 21 the the DT cord-022526-j9kg00qf 3950 22 mucosa mucosa NN cord-022526-j9kg00qf 3950 23 . . . cord-022526-j9kg00qf 3951 1 17 17 CD cord-022526-j9kg00qf 3951 2 , , , cord-022526-j9kg00qf 3951 3 155 155 CD cord-022526-j9kg00qf 3952 1 In in IN cord-022526-j9kg00qf 3952 2 doing do VBG cord-022526-j9kg00qf 3952 3 so so RB cord-022526-j9kg00qf 3952 4 , , , cord-022526-j9kg00qf 3952 5 the the DT cord-022526-j9kg00qf 3952 6 normal normal JJ cord-022526-j9kg00qf 3952 7 organisms organism NNS cord-022526-j9kg00qf 3952 8 compete compete VBP cord-022526-j9kg00qf 3952 9 more more RBR cord-022526-j9kg00qf 3952 10 successfully successfully RB cord-022526-j9kg00qf 3952 11 for for IN cord-022526-j9kg00qf 3952 12 this this DT cord-022526-j9kg00qf 3952 13 important important JJ cord-022526-j9kg00qf 3952 14 niche niche NN cord-022526-j9kg00qf 3952 15 . . . cord-022526-j9kg00qf 3953 1 Competition competition NN cord-022526-j9kg00qf 3953 2 for for IN cord-022526-j9kg00qf 3953 3 space space NN cord-022526-j9kg00qf 3953 4 and and CC cord-022526-j9kg00qf 3953 5 nutrients nutrient NNS cord-022526-j9kg00qf 3953 6 is be VBZ cord-022526-j9kg00qf 3953 7 an an DT cord-022526-j9kg00qf 3953 8 important important JJ cord-022526-j9kg00qf 3953 9 means mean NNS cord-022526-j9kg00qf 3953 10 of of IN cord-022526-j9kg00qf 3953 11 preventing prevent VBG cord-022526-j9kg00qf 3953 12 colonization colonization NN cord-022526-j9kg00qf 3953 13 and and CC cord-022526-j9kg00qf 3953 14 proliferation proliferation NN cord-022526-j9kg00qf 3953 15 of of IN cord-022526-j9kg00qf 3953 16 pathogenic pathogenic JJ cord-022526-j9kg00qf 3953 17 bacteria bacteria NNS cord-022526-j9kg00qf 3953 18 . . . cord-022526-j9kg00qf 3954 1 In in IN cord-022526-j9kg00qf 3954 2 addition addition NN cord-022526-j9kg00qf 3954 3 , , , cord-022526-j9kg00qf 3954 4 anaerobic anaerobic JJ cord-022526-j9kg00qf 3954 5 bacteria bacteria NNS cord-022526-j9kg00qf 3954 6 produce produce VBP cord-022526-j9kg00qf 3954 7 short short JJ cord-022526-j9kg00qf 3954 8 - - HYPH cord-022526-j9kg00qf 3954 9 chain chain NN cord-022526-j9kg00qf 3954 10 fatty fatty JJ cord-022526-j9kg00qf 3954 11 acids acid NNS cord-022526-j9kg00qf 3954 12 ( ( -LRB- cord-022526-j9kg00qf 3954 13 SCFAs SCFAs NNP cord-022526-j9kg00qf 3954 14 ) ) -RRB- cord-022526-j9kg00qf 3954 15 and and CC cord-022526-j9kg00qf 3954 16 other other JJ cord-022526-j9kg00qf 3954 17 metabolites metabolite NNS cord-022526-j9kg00qf 3954 18 that that WDT cord-022526-j9kg00qf 3954 19 are be VBP cord-022526-j9kg00qf 3954 20 toxic toxic JJ cord-022526-j9kg00qf 3954 21 to to TO cord-022526-j9kg00qf 3954 22 facultative facultative JJ cord-022526-j9kg00qf 3954 23 anaerobic anaerobic JJ cord-022526-j9kg00qf 3954 24 bacteria bacteria NNS cord-022526-j9kg00qf 3954 25 , , , cord-022526-j9kg00qf 3954 26 especially especially RB cord-022526-j9kg00qf 3954 27 in in IN cord-022526-j9kg00qf 3954 28 the the DT cord-022526-j9kg00qf 3954 29 conditions condition NNS cord-022526-j9kg00qf 3954 30 of of IN cord-022526-j9kg00qf 3954 31 the the DT cord-022526-j9kg00qf 3954 32 large large JJ cord-022526-j9kg00qf 3954 33 intestine intestine NN cord-022526-j9kg00qf 3954 34 . . . cord-022526-j9kg00qf 3955 1 16 16 CD cord-022526-j9kg00qf 3955 2 , , , cord-022526-j9kg00qf 3955 3 17 17 CD cord-022526-j9kg00qf 3955 4 , , , cord-022526-j9kg00qf 3955 5 155 155 CD cord-022526-j9kg00qf 3955 6 Organisms organism NNS cord-022526-j9kg00qf 3955 7 of of IN cord-022526-j9kg00qf 3955 8 the the DT cord-022526-j9kg00qf 3955 9 normal normal JJ cord-022526-j9kg00qf 3955 10 flora flora NNS cord-022526-j9kg00qf 3955 11 also also RB cord-022526-j9kg00qf 3955 12 produce produce VBP cord-022526-j9kg00qf 3955 13 bacteriocins bacteriocin NNS cord-022526-j9kg00qf 3955 14 that that WDT cord-022526-j9kg00qf 3955 15 inhibit inhibit VBP cord-022526-j9kg00qf 3955 16 growth growth NN cord-022526-j9kg00qf 3955 17 of of IN cord-022526-j9kg00qf 3955 18 potential potential JJ cord-022526-j9kg00qf 3955 19 pathogens pathogen NNS cord-022526-j9kg00qf 3955 20 . . . cord-022526-j9kg00qf 3956 1 16 16 CD cord-022526-j9kg00qf 3956 2 Antibiotics antibiotic NNS cord-022526-j9kg00qf 3956 3 that that WDT cord-022526-j9kg00qf 3956 4 deplete deplete VBP cord-022526-j9kg00qf 3956 5 the the DT cord-022526-j9kg00qf 3956 6 population population NN cord-022526-j9kg00qf 3956 7 of of IN cord-022526-j9kg00qf 3956 8 obligate obligate JJ cord-022526-j9kg00qf 3956 9 anaerobes anaerobe NNS cord-022526-j9kg00qf 3956 10 and and CC cord-022526-j9kg00qf 3956 11 streptococci streptococcus NNS cord-022526-j9kg00qf 3956 12 efficiently efficiently RB cord-022526-j9kg00qf 3956 13 decrease decrease VBP cord-022526-j9kg00qf 3956 14 colonization colonization NN cord-022526-j9kg00qf 3956 15 resistance resistance NN cord-022526-j9kg00qf 3956 16 . . . cord-022526-j9kg00qf 3957 1 16 16 CD cord-022526-j9kg00qf 3957 2 Production production NN cord-022526-j9kg00qf 3957 3 of of IN cord-022526-j9kg00qf 3957 4 fatty fatty JJ cord-022526-j9kg00qf 3957 5 acids acid NNS cord-022526-j9kg00qf 3957 6 diminishes diminish VBZ cord-022526-j9kg00qf 3957 7 , , , cord-022526-j9kg00qf 3957 8 thus thus RB cord-022526-j9kg00qf 3957 9 reducing reduce VBG cord-022526-j9kg00qf 3957 10 competition competition NN cord-022526-j9kg00qf 3957 11 for for IN cord-022526-j9kg00qf 3957 12 space space NN cord-022526-j9kg00qf 3957 13 and and CC cord-022526-j9kg00qf 3957 14 nutrients nutrient NNS cord-022526-j9kg00qf 3957 15 . . . cord-022526-j9kg00qf 3958 1 As as IN cord-022526-j9kg00qf 3958 2 a a DT cord-022526-j9kg00qf 3958 3 result result NN cord-022526-j9kg00qf 3958 4 , , , cord-022526-j9kg00qf 3958 5 gram gram NN cord-022526-j9kg00qf 3958 6 - - HYPH cord-022526-j9kg00qf 3958 7 negative negative JJ cord-022526-j9kg00qf 3958 8 enteric enteric JJ cord-022526-j9kg00qf 3958 9 bacteria bacteria NNS cord-022526-j9kg00qf 3958 10 such such JJ cord-022526-j9kg00qf 3958 11 as as IN cord-022526-j9kg00qf 3958 12 Salmonella Salmonella NNP cord-022526-j9kg00qf 3958 13 are be VBP cord-022526-j9kg00qf 3958 14 able able JJ cord-022526-j9kg00qf 3958 15 to to TO cord-022526-j9kg00qf 3958 16 proliferate proliferate VB cord-022526-j9kg00qf 3958 17 . . . cord-022526-j9kg00qf 3959 1 In in IN cord-022526-j9kg00qf 3959 2 addition addition NN cord-022526-j9kg00qf 3959 3 , , , cord-022526-j9kg00qf 3959 4 pathogenic pathogenic JJ cord-022526-j9kg00qf 3959 5 anaerobes anaerobe NNS cord-022526-j9kg00qf 3959 6 normally normally RB cord-022526-j9kg00qf 3959 7 found find VBN cord-022526-j9kg00qf 3959 8 in in IN cord-022526-j9kg00qf 3959 9 low low JJ cord-022526-j9kg00qf 3959 10 numbers number NNS cord-022526-j9kg00qf 3959 11 can can MD cord-022526-j9kg00qf 3959 12 proliferate proliferate VB cord-022526-j9kg00qf 3959 13 . . . cord-022526-j9kg00qf 3960 1 Antibiotic antibiotic JJ cord-022526-j9kg00qf 3960 2 - - HYPH cord-022526-j9kg00qf 3960 3 resistant resistant JJ cord-022526-j9kg00qf 3960 4 strains strain NNS cord-022526-j9kg00qf 3960 5 of of IN cord-022526-j9kg00qf 3960 6 bacteria bacteria NNS cord-022526-j9kg00qf 3960 7 , , , cord-022526-j9kg00qf 3960 8 especially especially RB cord-022526-j9kg00qf 3960 9 gram gram NN cord-022526-j9kg00qf 3960 10 - - HYPH cord-022526-j9kg00qf 3960 11 negative negative JJ cord-022526-j9kg00qf 3960 12 enteric enteric JJ cord-022526-j9kg00qf 3960 13 bacteria bacteria NNS cord-022526-j9kg00qf 3960 14 and and CC cord-022526-j9kg00qf 3960 15 possibly possibly RB cord-022526-j9kg00qf 3960 16 clostridia clostridia NNP cord-022526-j9kg00qf 3960 17 , , , cord-022526-j9kg00qf 3960 18 may may MD cord-022526-j9kg00qf 3960 19 be be VB cord-022526-j9kg00qf 3960 20 selected select VBN cord-022526-j9kg00qf 3960 21 by by IN cord-022526-j9kg00qf 3960 22 antibiotic antibiotic JJ cord-022526-j9kg00qf 3960 23 administration administration NN cord-022526-j9kg00qf 3960 24 , , , cord-022526-j9kg00qf 3960 25 allowing allow VBG cord-022526-j9kg00qf 3960 26 proliferation proliferation NN cord-022526-j9kg00qf 3960 27 of of IN cord-022526-j9kg00qf 3960 28 pathogenic pathogenic JJ cord-022526-j9kg00qf 3960 29 bacteria bacteria NNS cord-022526-j9kg00qf 3960 30 resistant resistant JJ cord-022526-j9kg00qf 3960 31 to to IN cord-022526-j9kg00qf 3960 32 many many JJ cord-022526-j9kg00qf 3960 33 antibiotics antibiotic NNS cord-022526-j9kg00qf 3960 34 . . . cord-022526-j9kg00qf 3961 1 156 156 CD cord-022526-j9kg00qf 3961 2 Obligate obligate VB cord-022526-j9kg00qf 3961 3 anaerobic anaerobic JJ cord-022526-j9kg00qf 3961 4 commensal commensal JJ cord-022526-j9kg00qf 3961 5 organisms organism NNS cord-022526-j9kg00qf 3961 6 , , , cord-022526-j9kg00qf 3961 7 perhaps perhaps RB cord-022526-j9kg00qf 3961 8 the the DT cord-022526-j9kg00qf 3961 9 most most RBS cord-022526-j9kg00qf 3961 10 critical critical JJ cord-022526-j9kg00qf 3961 11 group group NN cord-022526-j9kg00qf 3961 12 of of IN cord-022526-j9kg00qf 3961 13 microbes microbe NNS cord-022526-j9kg00qf 3961 14 for for IN cord-022526-j9kg00qf 3961 15 maintaining maintain VBG cord-022526-j9kg00qf 3961 16 colonization colonization NN cord-022526-j9kg00qf 3961 17 resistance resistance NN cord-022526-j9kg00qf 3961 18 , , , cord-022526-j9kg00qf 3961 19 are be VBP cord-022526-j9kg00qf 3961 20 usually usually RB cord-022526-j9kg00qf 3961 21 susceptible susceptible JJ cord-022526-j9kg00qf 3961 22 to to IN cord-022526-j9kg00qf 3961 23 macrolides macrolide NNS cord-022526-j9kg00qf 3961 24 , , , cord-022526-j9kg00qf 3961 25 tetracyclines tetracycline NNS cord-022526-j9kg00qf 3961 26 , , , cord-022526-j9kg00qf 3961 27 β β NN cord-022526-j9kg00qf 3961 28 - - HYPH cord-022526-j9kg00qf 3961 29 lactams lactam NNS cord-022526-j9kg00qf 3961 30 , , , cord-022526-j9kg00qf 3961 31 and and CC cord-022526-j9kg00qf 3961 32 lincosamides lincosamide NNS cord-022526-j9kg00qf 3961 33 , , , cord-022526-j9kg00qf 3961 34 perhaps perhaps RB cord-022526-j9kg00qf 3961 35 explaining explain VBG cord-022526-j9kg00qf 3961 36 the the DT cord-022526-j9kg00qf 3961 37 high high JJ cord-022526-j9kg00qf 3961 38 incidence incidence NN cord-022526-j9kg00qf 3961 39 of of IN cord-022526-j9kg00qf 3961 40 diarrhea diarrhea NN cord-022526-j9kg00qf 3961 41 associated associate VBN cord-022526-j9kg00qf 3961 42 with with IN cord-022526-j9kg00qf 3961 43 the the DT cord-022526-j9kg00qf 3961 44 administration administration NN cord-022526-j9kg00qf 3961 45 of of IN cord-022526-j9kg00qf 3961 46 these these DT cord-022526-j9kg00qf 3961 47 antibiotics antibiotic NNS cord-022526-j9kg00qf 3961 48 . . . cord-022526-j9kg00qf 3962 1 83 83 CD cord-022526-j9kg00qf 3963 1 In in IN cord-022526-j9kg00qf 3963 2 addition addition NN cord-022526-j9kg00qf 3963 3 to to IN cord-022526-j9kg00qf 3963 4 reduction reduction NN cord-022526-j9kg00qf 3963 5 of of IN cord-022526-j9kg00qf 3963 6 colonization colonization NN cord-022526-j9kg00qf 3963 7 resistance resistance NN cord-022526-j9kg00qf 3963 8 , , , cord-022526-j9kg00qf 3963 9 depletion depletion NN cord-022526-j9kg00qf 3963 10 of of IN cord-022526-j9kg00qf 3963 11 the the DT cord-022526-j9kg00qf 3963 12 normal normal JJ cord-022526-j9kg00qf 3963 13 anaerobic anaerobic JJ cord-022526-j9kg00qf 3963 14 microbial microbial JJ cord-022526-j9kg00qf 3963 15 population population NN cord-022526-j9kg00qf 3963 16 in in IN cord-022526-j9kg00qf 3963 17 the the DT cord-022526-j9kg00qf 3963 18 intestine intestine NN cord-022526-j9kg00qf 3963 19 decreases decrease VBZ cord-022526-j9kg00qf 3963 20 carbohydrate carbohydrate NN cord-022526-j9kg00qf 3963 21 fermentation fermentation NN cord-022526-j9kg00qf 3963 22 and and CC cord-022526-j9kg00qf 3963 23 production production NN cord-022526-j9kg00qf 3963 24 of of IN cord-022526-j9kg00qf 3963 25 SCFAs scfa NNS cord-022526-j9kg00qf 3963 26 , , , cord-022526-j9kg00qf 3963 27 which which WDT cord-022526-j9kg00qf 3963 28 contributes contribute VBZ cord-022526-j9kg00qf 3963 29 to to IN cord-022526-j9kg00qf 3963 30 the the DT cord-022526-j9kg00qf 3963 31 pathogenesis pathogenesis NN cord-022526-j9kg00qf 3963 32 of of IN cord-022526-j9kg00qf 3963 33 antibiotic antibiotic NN cord-022526-j9kg00qf 3963 34 - - HYPH cord-022526-j9kg00qf 3963 35 associated associated JJ cord-022526-j9kg00qf 3963 36 diarrhea diarrhea NN cord-022526-j9kg00qf 3963 37 by by IN cord-022526-j9kg00qf 3963 38 decreasing decrease VBG cord-022526-j9kg00qf 3963 39 absorption absorption NN cord-022526-j9kg00qf 3963 40 of of IN cord-022526-j9kg00qf 3963 41 sodium sodium NN cord-022526-j9kg00qf 3963 42 and and CC cord-022526-j9kg00qf 3963 43 water water NN cord-022526-j9kg00qf 3963 44 by by IN cord-022526-j9kg00qf 3963 45 the the DT cord-022526-j9kg00qf 3963 46 colonic colonic JJ cord-022526-j9kg00qf 3963 47 mucosa mucosa NN cord-022526-j9kg00qf 3963 48 . . . cord-022526-j9kg00qf 3964 1 157 157 CD cord-022526-j9kg00qf 3965 1 Ampicillin Ampicillin NNP cord-022526-j9kg00qf 3965 2 decreases decrease VBZ cord-022526-j9kg00qf 3965 3 colonic colonic JJ cord-022526-j9kg00qf 3965 4 fermentation fermentation NN cord-022526-j9kg00qf 3965 5 of of IN cord-022526-j9kg00qf 3965 6 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 3965 7 in in IN cord-022526-j9kg00qf 3965 8 human human JJ cord-022526-j9kg00qf 3965 9 beings being NNS cord-022526-j9kg00qf 3965 10 . . . cord-022526-j9kg00qf 3966 1 158 158 CD cord-022526-j9kg00qf 3966 2 Human human JJ cord-022526-j9kg00qf 3966 3 patients patient NNS cord-022526-j9kg00qf 3966 4 with with IN cord-022526-j9kg00qf 3966 5 antibioticassociated antibioticassociated JJ cord-022526-j9kg00qf 3966 6 diarrhea diarrhea NN cord-022526-j9kg00qf 3966 7 have have VBP cord-022526-j9kg00qf 3966 8 greatly greatly RB cord-022526-j9kg00qf 3966 9 impaired impair VBN cord-022526-j9kg00qf 3966 10 colonic colonic JJ cord-022526-j9kg00qf 3966 11 fermentation fermentation NN cord-022526-j9kg00qf 3966 12 and and CC cord-022526-j9kg00qf 3966 13 low low JJ cord-022526-j9kg00qf 3966 14 production production NN cord-022526-j9kg00qf 3966 15 of of IN cord-022526-j9kg00qf 3966 16 SCFAs scfa NNS cord-022526-j9kg00qf 3966 17 . . . cord-022526-j9kg00qf 3967 1 Erythromycin erythromycin NN cord-022526-j9kg00qf 3967 2 , , , cord-022526-j9kg00qf 3967 3 ampicillin ampicillin NN cord-022526-j9kg00qf 3967 4 , , , cord-022526-j9kg00qf 3967 5 or or CC cord-022526-j9kg00qf 3967 6 metronidazole metronidazole NN cord-022526-j9kg00qf 3967 7 treatment treatment NN cord-022526-j9kg00qf 3967 8 is be VBZ cord-022526-j9kg00qf 3967 9 associated associate VBN cord-022526-j9kg00qf 3967 10 with with IN cord-022526-j9kg00qf 3967 11 decreased decreased JJ cord-022526-j9kg00qf 3967 12 production production NN cord-022526-j9kg00qf 3967 13 of of IN cord-022526-j9kg00qf 3967 14 SCFAs scfa NNS cord-022526-j9kg00qf 3967 15 in in IN cord-022526-j9kg00qf 3967 16 patients patient NNS cord-022526-j9kg00qf 3967 17 with with IN cord-022526-j9kg00qf 3967 18 and and CC cord-022526-j9kg00qf 3967 19 without without IN cord-022526-j9kg00qf 3967 20 diarrhea diarrhea NN cord-022526-j9kg00qf 3967 21 . . . cord-022526-j9kg00qf 3968 1 88 88 CD cord-022526-j9kg00qf 3968 2 Absorption absorption NN cord-022526-j9kg00qf 3968 3 of of IN cord-022526-j9kg00qf 3968 4 sodium sodium NN cord-022526-j9kg00qf 3968 5 and and CC cord-022526-j9kg00qf 3968 6 water water NN cord-022526-j9kg00qf 3968 7 is be VBZ cord-022526-j9kg00qf 3968 8 stimulated stimulate VBN cord-022526-j9kg00qf 3968 9 by by IN cord-022526-j9kg00qf 3968 10 absorption absorption NN cord-022526-j9kg00qf 3968 11 of of IN cord-022526-j9kg00qf 3968 12 SCFAs scfa NNS cord-022526-j9kg00qf 3968 13 in in IN cord-022526-j9kg00qf 3968 14 the the DT cord-022526-j9kg00qf 3968 15 equine equine JJ cord-022526-j9kg00qf 3968 16 colon colon NN cord-022526-j9kg00qf 3968 17 , , , cord-022526-j9kg00qf 3968 18 suggesting suggest VBG cord-022526-j9kg00qf 3968 19 that that IN cord-022526-j9kg00qf 3968 20 reduction reduction NN cord-022526-j9kg00qf 3968 21 of of IN cord-022526-j9kg00qf 3968 22 colonic colonic JJ cord-022526-j9kg00qf 3968 23 SCFA SCFA NNP cord-022526-j9kg00qf 3968 24 content content NN cord-022526-j9kg00qf 3968 25 by by IN cord-022526-j9kg00qf 3968 26 antibiotic antibiotic NN cord-022526-j9kg00qf 3968 27 - - HYPH cord-022526-j9kg00qf 3968 28 induced induce VBN cord-022526-j9kg00qf 3968 29 depletion depletion NN cord-022526-j9kg00qf 3968 30 of of IN cord-022526-j9kg00qf 3968 31 anaerobic anaerobic JJ cord-022526-j9kg00qf 3968 32 flora flora NNS cord-022526-j9kg00qf 3968 33 has have VBZ cord-022526-j9kg00qf 3968 34 similar similar JJ cord-022526-j9kg00qf 3968 35 effects effect NNS cord-022526-j9kg00qf 3968 36 in in IN cord-022526-j9kg00qf 3968 37 horses horse NNS cord-022526-j9kg00qf 3968 38 as as IN cord-022526-j9kg00qf 3968 39 in in IN cord-022526-j9kg00qf 3968 40 human human JJ cord-022526-j9kg00qf 3968 41 beings being NNS cord-022526-j9kg00qf 3968 42 . . . cord-022526-j9kg00qf 3969 1 157 157 CD cord-022526-j9kg00qf 3969 2 Broad broad JJ cord-022526-j9kg00qf 3969 3 - - HYPH cord-022526-j9kg00qf 3969 4 spectrum spectrum NN cord-022526-j9kg00qf 3969 5 antibiotics antibiotic NNS cord-022526-j9kg00qf 3969 6 exert exert VBP cord-022526-j9kg00qf 3969 7 a a DT cord-022526-j9kg00qf 3969 8 more more RBR cord-022526-j9kg00qf 3969 9 profound profound JJ cord-022526-j9kg00qf 3969 10 effect effect NN cord-022526-j9kg00qf 3969 11 on on IN cord-022526-j9kg00qf 3969 12 the the DT cord-022526-j9kg00qf 3969 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3969 14 flora flora NNS cord-022526-j9kg00qf 3969 15 than than IN cord-022526-j9kg00qf 3969 16 narrow narrow JJ cord-022526-j9kg00qf 3969 17 - - HYPH cord-022526-j9kg00qf 3969 18 spectrum spectrum NN cord-022526-j9kg00qf 3969 19 antibiotics antibiotic NNS cord-022526-j9kg00qf 3969 20 . . . cord-022526-j9kg00qf 3970 1 Antibiotics antibiotic NNS cord-022526-j9kg00qf 3970 2 administered administer VBD cord-022526-j9kg00qf 3970 3 orally orally RB cord-022526-j9kg00qf 3970 4 , , , cord-022526-j9kg00qf 3970 5 especially especially RB cord-022526-j9kg00qf 3970 6 those those DT cord-022526-j9kg00qf 3970 7 that that WDT cord-022526-j9kg00qf 3970 8 are be VBP cord-022526-j9kg00qf 3970 9 poorly poorly RB cord-022526-j9kg00qf 3970 10 absorbed absorb VBN cord-022526-j9kg00qf 3970 11 , , , cord-022526-j9kg00qf 3970 12 are be VBP cord-022526-j9kg00qf 3970 13 more more RBR cord-022526-j9kg00qf 3970 14 likely likely JJ cord-022526-j9kg00qf 3970 15 to to TO cord-022526-j9kg00qf 3970 16 cause cause VB cord-022526-j9kg00qf 3970 17 diarrhea diarrhea NN cord-022526-j9kg00qf 3970 18 than than IN cord-022526-j9kg00qf 3970 19 are be VBP cord-022526-j9kg00qf 3970 20 parenterally parenterally RB cord-022526-j9kg00qf 3970 21 administered administer VBN cord-022526-j9kg00qf 3970 22 antibiotics antibiotic NNS cord-022526-j9kg00qf 3970 23 . . . cord-022526-j9kg00qf 3971 1 For for IN cord-022526-j9kg00qf 3971 2 instance instance NN cord-022526-j9kg00qf 3971 3 , , , cord-022526-j9kg00qf 3971 4 clindamycin clindamycin NN cord-022526-j9kg00qf 3971 5 is be VBZ cord-022526-j9kg00qf 3971 6 less less RBR cord-022526-j9kg00qf 3971 7 likely likely JJ cord-022526-j9kg00qf 3971 8 to to TO cord-022526-j9kg00qf 3971 9 cause cause VB cord-022526-j9kg00qf 3971 10 diarrhea diarrhea NN cord-022526-j9kg00qf 3971 11 in in IN cord-022526-j9kg00qf 3971 12 human human JJ cord-022526-j9kg00qf 3971 13 beings being NNS cord-022526-j9kg00qf 3971 14 when when WRB cord-022526-j9kg00qf 3971 15 administered administer VBN cord-022526-j9kg00qf 3971 16 intravenously intravenously RB cord-022526-j9kg00qf 3971 17 than than IN cord-022526-j9kg00qf 3971 18 when when WRB cord-022526-j9kg00qf 3971 19 administered administer VBN cord-022526-j9kg00qf 3971 20 orally orally RB cord-022526-j9kg00qf 3971 21 . . . cord-022526-j9kg00qf 3972 1 Antibiotics antibiotic NNS cord-022526-j9kg00qf 3972 2 with with IN cord-022526-j9kg00qf 3972 3 extensive extensive JJ cord-022526-j9kg00qf 3972 4 enterohepatic enterohepatic JJ cord-022526-j9kg00qf 3972 5 circulation circulation NN cord-022526-j9kg00qf 3972 6 , , , cord-022526-j9kg00qf 3972 7 such such JJ cord-022526-j9kg00qf 3972 8 as as IN cord-022526-j9kg00qf 3972 9 tetracyclines tetracycline NNS cord-022526-j9kg00qf 3972 10 and and CC cord-022526-j9kg00qf 3972 11 erythromycin erythromycin NNS cord-022526-j9kg00qf 3972 12 , , , cord-022526-j9kg00qf 3972 13 are be VBP cord-022526-j9kg00qf 3972 14 excreted excrete VBN cord-022526-j9kg00qf 3972 15 in in IN cord-022526-j9kg00qf 3972 16 high high JJ cord-022526-j9kg00qf 3972 17 concentrations concentration NNS cord-022526-j9kg00qf 3972 18 in in IN cord-022526-j9kg00qf 3972 19 the the DT cord-022526-j9kg00qf 3972 20 bile bile NN cord-022526-j9kg00qf 3972 21 and and CC cord-022526-j9kg00qf 3972 22 are be VBP cord-022526-j9kg00qf 3972 23 associated associate VBN cord-022526-j9kg00qf 3972 24 more more RBR cord-022526-j9kg00qf 3972 25 commonly commonly RB cord-022526-j9kg00qf 3972 26 with with IN cord-022526-j9kg00qf 3972 27 diarrhea diarrhea NN cord-022526-j9kg00qf 3972 28 than than IN cord-022526-j9kg00qf 3972 29 antibiotics antibiotic NNS cord-022526-j9kg00qf 3972 30 that that WDT cord-022526-j9kg00qf 3972 31 do do VBP cord-022526-j9kg00qf 3972 32 not not RB cord-022526-j9kg00qf 3972 33 undergo undergo VB cord-022526-j9kg00qf 3972 34 enterohepatic enterohepatic JJ cord-022526-j9kg00qf 3972 35 circulation circulation NN cord-022526-j9kg00qf 3972 36 . . . cord-022526-j9kg00qf 3973 1 159 159 CD cord-022526-j9kg00qf 3973 2 Antibiotics antibiotic NNS cord-022526-j9kg00qf 3973 3 may may MD cord-022526-j9kg00qf 3973 4 cause cause VB cord-022526-j9kg00qf 3973 5 diarrhea diarrhea NN cord-022526-j9kg00qf 3973 6 by by IN cord-022526-j9kg00qf 3973 7 means mean NNS cord-022526-j9kg00qf 3973 8 other other JJ cord-022526-j9kg00qf 3973 9 than than IN cord-022526-j9kg00qf 3973 10 by by IN cord-022526-j9kg00qf 3973 11 disrupting disrupt VBG cord-022526-j9kg00qf 3973 12 the the DT cord-022526-j9kg00qf 3973 13 normal normal JJ cord-022526-j9kg00qf 3973 14 flora flora NNS cord-022526-j9kg00qf 3973 15 . . . cord-022526-j9kg00qf 3974 1 Direct direct JJ cord-022526-j9kg00qf 3974 2 toxic toxic JJ cord-022526-j9kg00qf 3974 3 effects effect NNS cord-022526-j9kg00qf 3974 4 may may MD cord-022526-j9kg00qf 3974 5 play play VB cord-022526-j9kg00qf 3974 6 a a DT cord-022526-j9kg00qf 3974 7 role role NN cord-022526-j9kg00qf 3974 8 in in IN cord-022526-j9kg00qf 3974 9 producing produce VBG cord-022526-j9kg00qf 3974 10 irritation irritation NN cord-022526-j9kg00qf 3974 11 , , , cord-022526-j9kg00qf 3974 12 increasing increase VBG cord-022526-j9kg00qf 3974 13 secretion secretion NN cord-022526-j9kg00qf 3974 14 , , , cord-022526-j9kg00qf 3974 15 and and CC cord-022526-j9kg00qf 3974 16 disrupting disrupt VBG cord-022526-j9kg00qf 3974 17 motility motility NN cord-022526-j9kg00qf 3974 18 patterns pattern NNS cord-022526-j9kg00qf 3974 19 . . . cord-022526-j9kg00qf 3975 1 Tetracyclines tetracycline NNS cord-022526-j9kg00qf 3975 2 are be VBP cord-022526-j9kg00qf 3975 3 irritating irritating JJ cord-022526-j9kg00qf 3975 4 to to IN cord-022526-j9kg00qf 3975 5 the the DT cord-022526-j9kg00qf 3975 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3975 7 mucosa mucosa NN cord-022526-j9kg00qf 3975 8 and and CC cord-022526-j9kg00qf 3975 9 may may MD cord-022526-j9kg00qf 3975 10 cause cause VB cord-022526-j9kg00qf 3975 11 inflammation inflammation NN cord-022526-j9kg00qf 3975 12 and and CC cord-022526-j9kg00qf 3975 13 increase increase VB cord-022526-j9kg00qf 3975 14 secretion secretion NN cord-022526-j9kg00qf 3975 15 . . . cord-022526-j9kg00qf 3976 1 159 159 CD cord-022526-j9kg00qf 3976 2 Erythromycin Erythromycin NNP cord-022526-j9kg00qf 3976 3 has have VBZ cord-022526-j9kg00qf 3976 4 been be VBN cord-022526-j9kg00qf 3976 5 shown show VBN cord-022526-j9kg00qf 3976 6 to to TO cord-022526-j9kg00qf 3976 7 interact interact VB cord-022526-j9kg00qf 3976 8 with with IN cord-022526-j9kg00qf 3976 9 smooth smooth JJ cord-022526-j9kg00qf 3976 10 muscle muscle NN cord-022526-j9kg00qf 3976 11 cells cell NNS cord-022526-j9kg00qf 3976 12 , , , cord-022526-j9kg00qf 3976 13 stimulating stimulate VBG cord-022526-j9kg00qf 3976 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3976 15 motility motility NN cord-022526-j9kg00qf 3976 16 . . . cord-022526-j9kg00qf 3977 1 159 159 CD cord-022526-j9kg00qf 3977 2 , , , cord-022526-j9kg00qf 3977 3 160 160 CD cord-022526-j9kg00qf 3977 4 Normal normal JJ cord-022526-j9kg00qf 3977 5 peristalsis peristalsis NN cord-022526-j9kg00qf 3977 6 plays play VBZ cord-022526-j9kg00qf 3977 7 an an DT cord-022526-j9kg00qf 3977 8 important important JJ cord-022526-j9kg00qf 3977 9 role role NN cord-022526-j9kg00qf 3977 10 in in IN cord-022526-j9kg00qf 3977 11 suppressing suppress VBG cord-022526-j9kg00qf 3977 12 the the DT cord-022526-j9kg00qf 3977 13 population population NN cord-022526-j9kg00qf 3977 14 size size NN cord-022526-j9kg00qf 3977 15 of of IN cord-022526-j9kg00qf 3977 16 potentially potentially RB cord-022526-j9kg00qf 3977 17 pathogenic pathogenic JJ cord-022526-j9kg00qf 3977 18 bacteria bacteria NNS cord-022526-j9kg00qf 3977 19 . . . cord-022526-j9kg00qf 3978 1 Normally normally RB cord-022526-j9kg00qf 3978 2 , , , cord-022526-j9kg00qf 3978 3 bacteria bacteria NNS cord-022526-j9kg00qf 3978 4 that that WDT cord-022526-j9kg00qf 3978 5 are be VBP cord-022526-j9kg00qf 3978 6 prevented prevent VBN cord-022526-j9kg00qf 3978 7 from from IN cord-022526-j9kg00qf 3978 8 adhering adhere VBG cord-022526-j9kg00qf 3978 9 to to IN cord-022526-j9kg00qf 3978 10 the the DT cord-022526-j9kg00qf 3978 11 mucosa mucosa NN cord-022526-j9kg00qf 3978 12 by by IN cord-022526-j9kg00qf 3978 13 colonization colonization NN cord-022526-j9kg00qf 3978 14 resistance resistance NN cord-022526-j9kg00qf 3978 15 are be VBP cord-022526-j9kg00qf 3978 16 swept sweep VBN cord-022526-j9kg00qf 3978 17 aborally aborally RB cord-022526-j9kg00qf 3978 18 by by IN cord-022526-j9kg00qf 3978 19 peristalsis peristalsis NN cord-022526-j9kg00qf 3978 20 and and CC cord-022526-j9kg00qf 3978 21 are be VBP cord-022526-j9kg00qf 3978 22 excreted excrete VBN cord-022526-j9kg00qf 3978 23 in in IN cord-022526-j9kg00qf 3978 24 the the DT cord-022526-j9kg00qf 3978 25 feces fece NNS cord-022526-j9kg00qf 3978 26 . . . cord-022526-j9kg00qf 3979 1 Disruption disruption NN cord-022526-j9kg00qf 3979 2 of of IN cord-022526-j9kg00qf 3979 3 normal normal JJ cord-022526-j9kg00qf 3979 4 motility motility NN cord-022526-j9kg00qf 3979 5 patterns pattern NNS cord-022526-j9kg00qf 3979 6 may may MD cord-022526-j9kg00qf 3979 7 prevent prevent VB cord-022526-j9kg00qf 3979 8 clearance clearance NN cord-022526-j9kg00qf 3979 9 of of IN cord-022526-j9kg00qf 3979 10 pathogenic pathogenic JJ cord-022526-j9kg00qf 3979 11 bacteria bacteria NNS cord-022526-j9kg00qf 3979 12 , , , cord-022526-j9kg00qf 3979 13 contributing contribute VBG cord-022526-j9kg00qf 3979 14 to to IN cord-022526-j9kg00qf 3979 15 the the DT cord-022526-j9kg00qf 3979 16 colonization colonization NN cord-022526-j9kg00qf 3979 17 of of IN cord-022526-j9kg00qf 3979 18 mucosal mucosal JJ cord-022526-j9kg00qf 3979 19 surfaces surface NNS cord-022526-j9kg00qf 3979 20 . . . cord-022526-j9kg00qf 3980 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 3980 2 induced induce VBN cord-022526-j9kg00qf 3980 3 by by IN cord-022526-j9kg00qf 3980 4 antibiotics antibiotic NNS cord-022526-j9kg00qf 3980 5 usually usually RB cord-022526-j9kg00qf 3980 6 occurs occur VBZ cord-022526-j9kg00qf 3980 7 within within IN cord-022526-j9kg00qf 3980 8 7 7 CD cord-022526-j9kg00qf 3980 9 days day NNS cord-022526-j9kg00qf 3980 10 of of IN cord-022526-j9kg00qf 3980 11 antibiotic antibiotic JJ cord-022526-j9kg00qf 3980 12 administration administration NN cord-022526-j9kg00qf 3980 13 or or CC cord-022526-j9kg00qf 3980 14 can can MD cord-022526-j9kg00qf 3980 15 occur occur VB cord-022526-j9kg00qf 3980 16 several several JJ cord-022526-j9kg00qf 3980 17 days day NNS cord-022526-j9kg00qf 3980 18 after after IN cord-022526-j9kg00qf 3980 19 cessation cessation NN cord-022526-j9kg00qf 3980 20 of of IN cord-022526-j9kg00qf 3980 21 antibiotic antibiotic JJ cord-022526-j9kg00qf 3980 22 treatment treatment NN cord-022526-j9kg00qf 3980 23 . . . cord-022526-j9kg00qf 3981 1 The the DT cord-022526-j9kg00qf 3981 2 clinical clinical JJ cord-022526-j9kg00qf 3981 3 syndrome syndrome NN cord-022526-j9kg00qf 3981 4 of of IN cord-022526-j9kg00qf 3981 5 antibiotic antibiotic NN cord-022526-j9kg00qf 3981 6 - - HYPH cord-022526-j9kg00qf 3981 7 associated associated JJ cord-022526-j9kg00qf 3981 8 diarrhea diarrhea NN cord-022526-j9kg00qf 3981 9 can can MD cord-022526-j9kg00qf 3981 10 vary vary VB cord-022526-j9kg00qf 3981 11 from from IN cord-022526-j9kg00qf 3981 12 mild mild JJ cord-022526-j9kg00qf 3981 13 diarrhea diarrhea NN cord-022526-j9kg00qf 3981 14 to to IN cord-022526-j9kg00qf 3981 15 fulminant fulminant JJ cord-022526-j9kg00qf 3981 16 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3981 17 with with IN cord-022526-j9kg00qf 3981 18 severe severe JJ cord-022526-j9kg00qf 3981 19 diarrhea diarrhea NN cord-022526-j9kg00qf 3981 20 . . . cord-022526-j9kg00qf 3982 1 Mild mild JJ cord-022526-j9kg00qf 3982 2 cases case NNS cord-022526-j9kg00qf 3982 3 of of IN cord-022526-j9kg00qf 3982 4 diarrhea diarrhea NN cord-022526-j9kg00qf 3982 5 are be VBP cord-022526-j9kg00qf 3982 6 common common JJ cord-022526-j9kg00qf 3982 7 , , , cord-022526-j9kg00qf 3982 8 especially especially RB cord-022526-j9kg00qf 3982 9 in in IN cord-022526-j9kg00qf 3982 10 foals foal NNS cord-022526-j9kg00qf 3982 11 receiving receive VBG cord-022526-j9kg00qf 3982 12 erythromycin erythromycin NN cord-022526-j9kg00qf 3982 13 , , , cord-022526-j9kg00qf 3982 14 trimethoprim trimethoprim NN cord-022526-j9kg00qf 3982 15 - - HYPH cord-022526-j9kg00qf 3982 16 sulfonamide sulfonamide NN cord-022526-j9kg00qf 3982 17 combinations combination NNS cord-022526-j9kg00qf 3982 18 , , , cord-022526-j9kg00qf 3982 19 or or CC cord-022526-j9kg00qf 3982 20 rifampin rifampin NN cord-022526-j9kg00qf 3982 21 . . . cord-022526-j9kg00qf 3983 1 151 151 CD cord-022526-j9kg00qf 3983 2 , , , cord-022526-j9kg00qf 3983 3 161 161 CD cord-022526-j9kg00qf 3983 4 Mild mild JJ cord-022526-j9kg00qf 3983 5 cases case NNS cord-022526-j9kg00qf 3983 6 of of IN cord-022526-j9kg00qf 3983 7 diarrhea diarrhea NN cord-022526-j9kg00qf 3983 8 are be VBP cord-022526-j9kg00qf 3983 9 usually usually RB cord-022526-j9kg00qf 3983 10 not not RB cord-022526-j9kg00qf 3983 11 clinically clinically RB cord-022526-j9kg00qf 3983 12 significant significant JJ cord-022526-j9kg00qf 3983 13 . . . cord-022526-j9kg00qf 3984 1 However however RB cord-022526-j9kg00qf 3984 2 , , , cord-022526-j9kg00qf 3984 3 acute acute JJ cord-022526-j9kg00qf 3984 4 , , , cord-022526-j9kg00qf 3984 5 severe severe JJ cord-022526-j9kg00qf 3984 6 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3984 7 can can MD cord-022526-j9kg00qf 3984 8 occur occur VB cord-022526-j9kg00qf 3984 9 in in IN cord-022526-j9kg00qf 3984 10 all all DT cord-022526-j9kg00qf 3984 11 ages age NNS cord-022526-j9kg00qf 3984 12 of of IN cord-022526-j9kg00qf 3984 13 horses horse NNS cord-022526-j9kg00qf 3984 14 receiving receive VBG cord-022526-j9kg00qf 3984 15 antibiotics antibiotic NNS cord-022526-j9kg00qf 3984 16 and and CC cord-022526-j9kg00qf 3984 17 can can MD cord-022526-j9kg00qf 3984 18 be be VB cord-022526-j9kg00qf 3984 19 life life NN cord-022526-j9kg00qf 3984 20 threatening threaten VBG cord-022526-j9kg00qf 3984 21 . . . cord-022526-j9kg00qf 3985 1 Clinical clinical JJ cord-022526-j9kg00qf 3985 2 signs sign NNS cord-022526-j9kg00qf 3985 3 are be VBP cord-022526-j9kg00qf 3985 4 identical identical JJ cord-022526-j9kg00qf 3985 5 to to IN cord-022526-j9kg00qf 3985 6 other other JJ cord-022526-j9kg00qf 3985 7 causes cause NNS cord-022526-j9kg00qf 3985 8 of of IN cord-022526-j9kg00qf 3985 9 acute acute JJ cord-022526-j9kg00qf 3985 10 enterocolitis enterocolitis NN cord-022526-j9kg00qf 3985 11 . . . cord-022526-j9kg00qf 3986 1 Severe severe JJ cord-022526-j9kg00qf 3986 2 , , , cord-022526-j9kg00qf 3986 3 dehydrating dehydrate VBG cord-022526-j9kg00qf 3986 4 diarrhea diarrhea NN cord-022526-j9kg00qf 3986 5 , , , cord-022526-j9kg00qf 3986 6 endotoxemia endotoxemia NN cord-022526-j9kg00qf 3986 7 , , , cord-022526-j9kg00qf 3986 8 sepsis sepsis NN cord-022526-j9kg00qf 3986 9 , , , cord-022526-j9kg00qf 3986 10 and and CC cord-022526-j9kg00qf 3986 11 shock shock NN cord-022526-j9kg00qf 3986 12 may may MD cord-022526-j9kg00qf 3986 13 occur occur VB cord-022526-j9kg00qf 3986 14 . . . cord-022526-j9kg00qf 3987 1 Hemoconcentration Hemoconcentration NNP cord-022526-j9kg00qf 3987 2 , , , cord-022526-j9kg00qf 3987 3 neutropenia neutropenia NN cord-022526-j9kg00qf 3987 4 , , , cord-022526-j9kg00qf 3987 5 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 3987 6 , , , cord-022526-j9kg00qf 3987 7 and and CC cord-022526-j9kg00qf 3987 8 electrolyte electrolyte NN cord-022526-j9kg00qf 3987 9 and and CC cord-022526-j9kg00qf 3987 10 acid acid NN cord-022526-j9kg00qf 3987 11 - - HYPH cord-022526-j9kg00qf 3987 12 base base NN cord-022526-j9kg00qf 3987 13 imbalances imbalance NNS cord-022526-j9kg00qf 3987 14 are be VBP cord-022526-j9kg00qf 3987 15 common common JJ cord-022526-j9kg00qf 3987 16 . . . cord-022526-j9kg00qf 3988 1 Severe severe JJ cord-022526-j9kg00qf 3988 2 hyponatremia hyponatremia NN cord-022526-j9kg00qf 3988 3 may may MD cord-022526-j9kg00qf 3988 4 occur occur VB cord-022526-j9kg00qf 3988 5 in in IN cord-022526-j9kg00qf 3988 6 foals foal NNS cord-022526-j9kg00qf 3988 7 with with IN cord-022526-j9kg00qf 3988 8 antibiotic antibiotic NN cord-022526-j9kg00qf 3988 9 - - HYPH cord-022526-j9kg00qf 3988 10 associated associated JJ cord-022526-j9kg00qf 3988 11 diarrhea diarrhea NN cord-022526-j9kg00qf 3988 12 , , , cord-022526-j9kg00qf 3988 13 especially especially RB cord-022526-j9kg00qf 3988 14 if if IN cord-022526-j9kg00qf 3988 15 trimethoprimsulfonamide trimethoprimsulfonamide NN cord-022526-j9kg00qf 3988 16 and and CC cord-022526-j9kg00qf 3988 17 rifampin rifampin NN cord-022526-j9kg00qf 3988 18 combinations combination NNS cord-022526-j9kg00qf 3988 19 are be VBP cord-022526-j9kg00qf 3988 20 the the DT cord-022526-j9kg00qf 3988 21 cause cause NN cord-022526-j9kg00qf 3988 22 . . . cord-022526-j9kg00qf 3989 1 161 161 CD cord-022526-j9kg00qf 3989 2 More more RBR cord-022526-j9kg00qf 3989 3 detailed detailed JJ cord-022526-j9kg00qf 3989 4 descriptions description NNS cord-022526-j9kg00qf 3989 5 of of IN cord-022526-j9kg00qf 3989 6 the the DT cord-022526-j9kg00qf 3989 7 clinical clinical JJ cord-022526-j9kg00qf 3989 8 and and CC cord-022526-j9kg00qf 3989 9 laboratory laboratory NN cord-022526-j9kg00qf 3989 10 findings finding NNS cord-022526-j9kg00qf 3989 11 were be VBD cord-022526-j9kg00qf 3989 12 given give VBN cord-022526-j9kg00qf 3989 13 previously previously RB cord-022526-j9kg00qf 3989 14 . . . cord-022526-j9kg00qf 3990 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 3990 2 is be VBZ cord-022526-j9kg00qf 3990 3 presumptive presumptive JJ cord-022526-j9kg00qf 3990 4 , , , cord-022526-j9kg00qf 3990 5 because because IN cord-022526-j9kg00qf 3990 6 definitive definitive JJ cord-022526-j9kg00qf 3990 7 diagnosis diagnosis NN cord-022526-j9kg00qf 3990 8 of of IN cord-022526-j9kg00qf 3990 9 antibiotic antibiotic NN cord-022526-j9kg00qf 3990 10 - - HYPH cord-022526-j9kg00qf 3990 11 associated associated JJ cord-022526-j9kg00qf 3990 12 diarrhea diarrhea NN cord-022526-j9kg00qf 3990 13 is be VBZ cord-022526-j9kg00qf 3990 14 impossible impossible JJ cord-022526-j9kg00qf 3990 15 . . . cord-022526-j9kg00qf 3991 1 Fecal fecal JJ cord-022526-j9kg00qf 3991 2 culture culture NN cord-022526-j9kg00qf 3991 3 and and CC cord-022526-j9kg00qf 3991 4 PCR PCR NNP cord-022526-j9kg00qf 3991 5 testing testing NN cord-022526-j9kg00qf 3991 6 may may MD cord-022526-j9kg00qf 3991 7 reveal reveal VB cord-022526-j9kg00qf 3991 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 3991 9 or or CC cord-022526-j9kg00qf 3991 10 Clostridium clostridium NN cord-022526-j9kg00qf 3991 11 infection infection NN cord-022526-j9kg00qf 3991 12 . . . cord-022526-j9kg00qf 3992 1 Toxicity toxicity NN cord-022526-j9kg00qf 3992 2 resulting result VBG cord-022526-j9kg00qf 3992 3 from from IN cord-022526-j9kg00qf 3992 4 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 3992 5 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 3992 6 drug drug NN cord-022526-j9kg00qf 3992 7 ( ( -LRB- cord-022526-j9kg00qf 3992 8 NSAID NSAID NNP cord-022526-j9kg00qf 3992 9 ) ) -RRB- cord-022526-j9kg00qf 3992 10 administration administration NN cord-022526-j9kg00qf 3992 11 has have VBZ cord-022526-j9kg00qf 3992 12 been be VBN cord-022526-j9kg00qf 3992 13 well well RB cord-022526-j9kg00qf 3992 14 documented document VBN cord-022526-j9kg00qf 3992 15 in in IN cord-022526-j9kg00qf 3992 16 several several JJ cord-022526-j9kg00qf 3992 17 species specie NNS cord-022526-j9kg00qf 3992 18 , , , cord-022526-j9kg00qf 3992 19 including include VBG cord-022526-j9kg00qf 3992 20 horses horse NNS cord-022526-j9kg00qf 3992 21 . . . cord-022526-j9kg00qf 3993 1 [ [ -LRB- cord-022526-j9kg00qf 3993 2 162 162 CD cord-022526-j9kg00qf 3993 3 ] ] -RRB- cord-022526-j9kg00qf 3993 4 [ [ -LRB- cord-022526-j9kg00qf 3993 5 163 163 CD cord-022526-j9kg00qf 3993 6 ] ] -RRB- cord-022526-j9kg00qf 3993 7 [ [ -LRB- cord-022526-j9kg00qf 3993 8 164 164 CD cord-022526-j9kg00qf 3993 9 ] ] -RRB- cord-022526-j9kg00qf 3994 1 [ [ -LRB- cord-022526-j9kg00qf 3994 2 165 165 CD cord-022526-j9kg00qf 3994 3 ] ] -RRB- cord-022526-j9kg00qf 3994 4 [ [ -LRB- cord-022526-j9kg00qf 3994 5 166 166 CD cord-022526-j9kg00qf 3994 6 ] ] -RRB- cord-022526-j9kg00qf 3994 7 [ [ -LRB- cord-022526-j9kg00qf 3994 8 167 167 CD cord-022526-j9kg00qf 3994 9 ] ] -RRB- cord-022526-j9kg00qf 3994 10 [ [ -LRB- cord-022526-j9kg00qf 3994 11 168 168 CD cord-022526-j9kg00qf 3994 12 ] ] -RRB- cord-022526-j9kg00qf 3995 1 In in IN cord-022526-j9kg00qf 3995 2 horses horse NNS cord-022526-j9kg00qf 3995 3 and and CC cord-022526-j9kg00qf 3995 4 human human JJ cord-022526-j9kg00qf 3995 5 beings being NNS cord-022526-j9kg00qf 3995 6 , , , cord-022526-j9kg00qf 3995 7 NSAID NSAID NNP cord-022526-j9kg00qf 3995 8 toxicity toxicity NN cord-022526-j9kg00qf 3995 9 is be VBZ cord-022526-j9kg00qf 3995 10 manifested manifest VBN cord-022526-j9kg00qf 3995 11 by by IN cord-022526-j9kg00qf 3995 12 renal renal JJ cord-022526-j9kg00qf 3995 13 and and CC cord-022526-j9kg00qf 3995 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3995 15 disease disease NN cord-022526-j9kg00qf 3995 16 . . . cord-022526-j9kg00qf 3996 1 Elderly elderly JJ cord-022526-j9kg00qf 3996 2 human human JJ cord-022526-j9kg00qf 3996 3 patients patient NNS cord-022526-j9kg00qf 3996 4 are be VBP cord-022526-j9kg00qf 3996 5 more more RBR cord-022526-j9kg00qf 3996 6 susceptible susceptible JJ cord-022526-j9kg00qf 3996 7 to to IN cord-022526-j9kg00qf 3996 8 NSAID nsaid NN cord-022526-j9kg00qf 3996 9 toxicity toxicity NN cord-022526-j9kg00qf 3996 10 , , , cord-022526-j9kg00qf 3996 11 but but CC cord-022526-j9kg00qf 3996 12 the the DT cord-022526-j9kg00qf 3996 13 effects effect NNS cord-022526-j9kg00qf 3996 14 of of IN cord-022526-j9kg00qf 3996 15 age age NN cord-022526-j9kg00qf 3996 16 on on IN cord-022526-j9kg00qf 3996 17 NSAID NSAID NNP cord-022526-j9kg00qf 3996 18 toxicity toxicity NN cord-022526-j9kg00qf 3996 19 in in IN cord-022526-j9kg00qf 3996 20 horses horse NNS cord-022526-j9kg00qf 3996 21 are be VBP cord-022526-j9kg00qf 3996 22 less less RBR cord-022526-j9kg00qf 3996 23 well well RB cord-022526-j9kg00qf 3996 24 defined define VBN cord-022526-j9kg00qf 3996 25 . . . cord-022526-j9kg00qf 3997 1 Foals foal NNS cord-022526-j9kg00qf 3997 2 are be VBP cord-022526-j9kg00qf 3997 3 considered consider VBN cord-022526-j9kg00qf 3997 4 to to TO cord-022526-j9kg00qf 3997 5 be be VB cord-022526-j9kg00qf 3997 6 more more RBR cord-022526-j9kg00qf 3997 7 susceptible susceptible JJ cord-022526-j9kg00qf 3997 8 than than IN cord-022526-j9kg00qf 3997 9 adult adult NN cord-022526-j9kg00qf 3997 10 horses horse NNS cord-022526-j9kg00qf 3997 11 to to IN cord-022526-j9kg00qf 3997 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3997 13 disease disease NN cord-022526-j9kg00qf 3997 14 following follow VBG cord-022526-j9kg00qf 3997 15 NSAID NSAID NNP cord-022526-j9kg00qf 3997 16 administration administration NN cord-022526-j9kg00qf 3997 17 , , , cord-022526-j9kg00qf 3997 18 and and CC cord-022526-j9kg00qf 3997 19 ponies pony NNS cord-022526-j9kg00qf 3997 20 may may MD cord-022526-j9kg00qf 3997 21 be be VB cord-022526-j9kg00qf 3997 22 more more RBR cord-022526-j9kg00qf 3997 23 susceptible susceptible JJ cord-022526-j9kg00qf 3997 24 than than IN cord-022526-j9kg00qf 3997 25 horses horse NNS cord-022526-j9kg00qf 3997 26 . . . cord-022526-j9kg00qf 3998 1 All all DT cord-022526-j9kg00qf 3998 2 NSAIDs nsaid NNS cord-022526-j9kg00qf 3998 3 are be VBP cord-022526-j9kg00qf 3998 4 capable capable JJ cord-022526-j9kg00qf 3998 5 of of IN cord-022526-j9kg00qf 3998 6 inducing induce VBG cord-022526-j9kg00qf 3998 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 3998 8 and and CC cord-022526-j9kg00qf 3998 9 renal renal JJ cord-022526-j9kg00qf 3998 10 damage damage NN cord-022526-j9kg00qf 3998 11 at at IN cord-022526-j9kg00qf 3998 12 toxic toxic JJ cord-022526-j9kg00qf 3998 13 concentrations concentration NNS cord-022526-j9kg00qf 3998 14 , , , cord-022526-j9kg00qf 3998 15 and and CC cord-022526-j9kg00qf 3998 16 the the DT cord-022526-j9kg00qf 3998 17 toxicity toxicity NN cord-022526-j9kg00qf 3998 18 is be VBZ cord-022526-j9kg00qf 3998 19 not not RB cord-022526-j9kg00qf 3998 20 significantly significantly RB cord-022526-j9kg00qf 3998 21 different different JJ cord-022526-j9kg00qf 3998 22 among among IN cord-022526-j9kg00qf 3998 23 products product NNS cord-022526-j9kg00qf 3998 24 . . . cord-022526-j9kg00qf 3999 1 Aspirin aspirin NN cord-022526-j9kg00qf 3999 2 is be VBZ cord-022526-j9kg00qf 3999 3 potentially potentially RB cord-022526-j9kg00qf 3999 4 more more RBR cord-022526-j9kg00qf 3999 5 toxic toxic JJ cord-022526-j9kg00qf 3999 6 than than IN cord-022526-j9kg00qf 3999 7 other other JJ cord-022526-j9kg00qf 3999 8 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 3999 9 because because IN cord-022526-j9kg00qf 3999 10 it -PRON- PRP cord-022526-j9kg00qf 3999 11 irreversibly irreversibly RB cord-022526-j9kg00qf 3999 12 inactivates inactivate VBZ cord-022526-j9kg00qf 3999 13 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 3999 14 by by IN cord-022526-j9kg00qf 3999 15 acetylation acetylation NN cord-022526-j9kg00qf 3999 16 , , , cord-022526-j9kg00qf 3999 17 whereas whereas IN cord-022526-j9kg00qf 3999 18 other other JJ cord-022526-j9kg00qf 3999 19 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 3999 20 reversibly reversibly RB cord-022526-j9kg00qf 3999 21 inhibit inhibit VBP cord-022526-j9kg00qf 3999 22 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 3999 23 . . . cord-022526-j9kg00qf 4000 1 162 162 CD cord-022526-j9kg00qf 4001 1 However however RB cord-022526-j9kg00qf 4001 2 , , , cord-022526-j9kg00qf 4001 3 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4001 4 is be VBZ cord-022526-j9kg00qf 4001 5 the the DT cord-022526-j9kg00qf 4001 6 drug drug NN cord-022526-j9kg00qf 4001 7 most most RBS cord-022526-j9kg00qf 4001 8 commonly commonly RB cord-022526-j9kg00qf 4001 9 reported report VBN cord-022526-j9kg00qf 4001 10 to to TO cord-022526-j9kg00qf 4001 11 cause cause VB cord-022526-j9kg00qf 4001 12 toxicity toxicity NN cord-022526-j9kg00qf 4001 13 in in IN cord-022526-j9kg00qf 4001 14 horses horse NNS cord-022526-j9kg00qf 4001 15 , , , cord-022526-j9kg00qf 4001 16 perhaps perhaps RB cord-022526-j9kg00qf 4001 17 because because IN cord-022526-j9kg00qf 4001 18 of of IN cord-022526-j9kg00qf 4001 19 its -PRON- PRP$ cord-022526-j9kg00qf 4001 20 widespread widespread JJ cord-022526-j9kg00qf 4001 21 use use NN cord-022526-j9kg00qf 4001 22 by by IN cord-022526-j9kg00qf 4001 23 veterinarians veterinarian NNS cord-022526-j9kg00qf 4001 24 and and CC cord-022526-j9kg00qf 4001 25 horse horse NN cord-022526-j9kg00qf 4001 26 owners owner NNS cord-022526-j9kg00qf 4001 27 . . . cord-022526-j9kg00qf 4002 1 Phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 4002 2 toxicity toxicity NN cord-022526-j9kg00qf 4002 3 in in IN cord-022526-j9kg00qf 4002 4 horses horse NNS cord-022526-j9kg00qf 4002 5 is be VBZ cord-022526-j9kg00qf 4002 6 characterized characterize VBN cord-022526-j9kg00qf 4002 7 by by IN cord-022526-j9kg00qf 4002 8 mucosal mucosal JJ cord-022526-j9kg00qf 4002 9 ulceration ulceration NN cord-022526-j9kg00qf 4002 10 throughout throughout IN cord-022526-j9kg00qf 4002 11 the the DT cord-022526-j9kg00qf 4002 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4002 13 tract tract NN cord-022526-j9kg00qf 4002 14 , , , cord-022526-j9kg00qf 4002 15 oral oral JJ cord-022526-j9kg00qf 4002 16 ulceration ulceration NN cord-022526-j9kg00qf 4002 17 , , , cord-022526-j9kg00qf 4002 18 renal renal JJ cord-022526-j9kg00qf 4002 19 papillary papillary JJ cord-022526-j9kg00qf 4002 20 necrosis necrosis NN cord-022526-j9kg00qf 4002 21 , , , cord-022526-j9kg00qf 4002 22 vasculopathy vasculopathy NNP cord-022526-j9kg00qf 4002 23 , , , cord-022526-j9kg00qf 4002 24 thrombosis thrombosis NN cord-022526-j9kg00qf 4002 25 , , , cord-022526-j9kg00qf 4002 26 and and CC cord-022526-j9kg00qf 4002 27 protein protein NN cord-022526-j9kg00qf 4002 28 - - HYPH cord-022526-j9kg00qf 4002 29 losing lose VBG cord-022526-j9kg00qf 4002 30 enteropathy enteropathy NNP cord-022526-j9kg00qf 4002 31 with with IN cord-022526-j9kg00qf 4002 32 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4002 33 . . . cord-022526-j9kg00qf 4003 1 [ [ -LRB- cord-022526-j9kg00qf 4003 2 164 164 CD cord-022526-j9kg00qf 4003 3 ] ] -RRB- cord-022526-j9kg00qf 4003 4 [ [ -LRB- cord-022526-j9kg00qf 4003 5 165 165 CD cord-022526-j9kg00qf 4003 6 ] ] -RRB- cord-022526-j9kg00qf 4004 1 [ [ -LRB- cord-022526-j9kg00qf 4004 2 166 166 CD cord-022526-j9kg00qf 4004 3 ] ] -RRB- cord-022526-j9kg00qf 4005 1 This this DT cord-022526-j9kg00qf 4005 2 discussion discussion NN cord-022526-j9kg00qf 4005 3 focuses focus VBZ cord-022526-j9kg00qf 4005 4 on on IN cord-022526-j9kg00qf 4005 5 the the DT cord-022526-j9kg00qf 4005 6 toxic toxic JJ cord-022526-j9kg00qf 4005 7 effects effect NNS cord-022526-j9kg00qf 4005 8 of of IN cord-022526-j9kg00qf 4005 9 NSAIDs nsaid NNS cord-022526-j9kg00qf 4005 10 on on IN cord-022526-j9kg00qf 4005 11 the the DT cord-022526-j9kg00qf 4005 12 large large JJ cord-022526-j9kg00qf 4005 13 intestine intestine NN cord-022526-j9kg00qf 4005 14 but but CC cord-022526-j9kg00qf 4005 15 necessarily necessarily RB cord-022526-j9kg00qf 4005 16 includes include VBZ cord-022526-j9kg00qf 4005 17 elements element NNS cord-022526-j9kg00qf 4005 18 of of IN cord-022526-j9kg00qf 4005 19 upper upper JJ cord-022526-j9kg00qf 4005 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4005 21 and and CC cord-022526-j9kg00qf 4005 22 renal renal JJ cord-022526-j9kg00qf 4005 23 disease disease NN cord-022526-j9kg00qf 4005 24 . . . cord-022526-j9kg00qf 4006 1 Horses horse NNS cord-022526-j9kg00qf 4006 2 with with IN cord-022526-j9kg00qf 4006 3 large large JJ cord-022526-j9kg00qf 4006 4 intestinal intestinal JJ cord-022526-j9kg00qf 4006 5 disease disease NN cord-022526-j9kg00qf 4006 6 resulting result VBG cord-022526-j9kg00qf 4006 7 from from IN cord-022526-j9kg00qf 4006 8 NSAID NSAID NNP cord-022526-j9kg00qf 4006 9 toxicity toxicity NN cord-022526-j9kg00qf 4006 10 generally generally RB cord-022526-j9kg00qf 4006 11 are be VBP cord-022526-j9kg00qf 4006 12 receiving receive VBG cord-022526-j9kg00qf 4006 13 inappropriately inappropriately RB cord-022526-j9kg00qf 4006 14 large large JJ cord-022526-j9kg00qf 4006 15 doses dose NNS cord-022526-j9kg00qf 4006 16 . . . cord-022526-j9kg00qf 4007 1 The the DT cord-022526-j9kg00qf 4007 2 dosage dosage NN cord-022526-j9kg00qf 4007 3 regimen regimen NN cord-022526-j9kg00qf 4007 4 recommended recommend VBD cord-022526-j9kg00qf 4007 5 for for IN cord-022526-j9kg00qf 4007 6 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4007 7 ( ( -LRB- cord-022526-j9kg00qf 4007 8 4.4 4.4 CD cord-022526-j9kg00qf 4007 9 mg mg NNP cord-022526-j9kg00qf 4007 10 / / SYM cord-022526-j9kg00qf 4007 11 kg kg NNS cord-022526-j9kg00qf 4007 12 twice twice RB cord-022526-j9kg00qf 4007 13 in in IN cord-022526-j9kg00qf 4007 14 1 1 CD cord-022526-j9kg00qf 4007 15 day day NN cord-022526-j9kg00qf 4008 1 and and CC cord-022526-j9kg00qf 4008 2 then then RB cord-022526-j9kg00qf 4008 3 2.2 2.2 CD cord-022526-j9kg00qf 4008 4 mg mg NNP cord-022526-j9kg00qf 4008 5 / / SYM cord-022526-j9kg00qf 4008 6 kg kg NNS cord-022526-j9kg00qf 4008 7 twice twice RB cord-022526-j9kg00qf 4008 8 daily daily RB cord-022526-j9kg00qf 4008 9 ) ) -RRB- cord-022526-j9kg00qf 4008 10 is be VBZ cord-022526-j9kg00qf 4008 11 considered consider VBN cord-022526-j9kg00qf 4008 12 to to TO cord-022526-j9kg00qf 4008 13 be be VB cord-022526-j9kg00qf 4008 14 safe safe JJ cord-022526-j9kg00qf 4008 15 . . . cord-022526-j9kg00qf 4009 1 Experimental experimental JJ cord-022526-j9kg00qf 4009 2 studies study NNS cord-022526-j9kg00qf 4009 3 in in IN cord-022526-j9kg00qf 4009 4 horses horse NNS cord-022526-j9kg00qf 4009 5 , , , cord-022526-j9kg00qf 4009 6 however however RB cord-022526-j9kg00qf 4009 7 , , , cord-022526-j9kg00qf 4009 8 have have VBP cord-022526-j9kg00qf 4009 9 shown show VBN cord-022526-j9kg00qf 4009 10 toxicity toxicity NN cord-022526-j9kg00qf 4009 11 to to TO cord-022526-j9kg00qf 4009 12 occur occur VB cord-022526-j9kg00qf 4009 13 when when WRB cord-022526-j9kg00qf 4009 14 greater great JJR cord-022526-j9kg00qf 4009 15 than than IN cord-022526-j9kg00qf 4009 16 the the DT cord-022526-j9kg00qf 4009 17 recommended recommend VBN cord-022526-j9kg00qf 4009 18 dosage dosage NN cord-022526-j9kg00qf 4009 19 ( ( -LRB- cord-022526-j9kg00qf 4009 20 6.6 6.6 CD cord-022526-j9kg00qf 4009 21 mg mg NNP cord-022526-j9kg00qf 4009 22 / / SYM cord-022526-j9kg00qf 4009 23 kg kg NNP cord-022526-j9kg00qf 4009 24 / / SYM cord-022526-j9kg00qf 4009 25 day day NN cord-022526-j9kg00qf 4009 26 ) ) -RRB- cord-022526-j9kg00qf 4009 27 is be VBZ cord-022526-j9kg00qf 4009 28 administered administer VBN cord-022526-j9kg00qf 4009 29 for for IN cord-022526-j9kg00qf 4009 30 several several JJ cord-022526-j9kg00qf 4009 31 days day NNS cord-022526-j9kg00qf 4009 32 . . . cord-022526-j9kg00qf 4010 1 164 164 CD cord-022526-j9kg00qf 4010 2 , , , cord-022526-j9kg00qf 4010 3 165 165 CD cord-022526-j9kg00qf 4011 1 In in IN cord-022526-j9kg00qf 4011 2 most most RBS cord-022526-j9kg00qf 4011 3 reported report VBN cord-022526-j9kg00qf 4011 4 cases case NNS cord-022526-j9kg00qf 4011 5 of of IN cord-022526-j9kg00qf 4011 6 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 4011 7 toxicosis toxicosis NN cord-022526-j9kg00qf 4011 8 horses horse NNS cord-022526-j9kg00qf 4011 9 were be VBD cord-022526-j9kg00qf 4011 10 receiving receive VBG cord-022526-j9kg00qf 4011 11 higher high JJR cord-022526-j9kg00qf 4011 12 than than IN cord-022526-j9kg00qf 4011 13 recommended recommend VBN cord-022526-j9kg00qf 4011 14 dosages dosage NNS cord-022526-j9kg00qf 4011 15 . . . cord-022526-j9kg00qf 4012 1 166 166 CD cord-022526-j9kg00qf 4012 2 , , , cord-022526-j9kg00qf 4012 3 168 168 CD cord-022526-j9kg00qf 4012 4 , , , cord-022526-j9kg00qf 4012 5 169 169 CD cord-022526-j9kg00qf 4013 1 Regardless regardless RB cord-022526-j9kg00qf 4013 2 , , , cord-022526-j9kg00qf 4013 3 administration administration NN cord-022526-j9kg00qf 4013 4 of of IN cord-022526-j9kg00qf 4013 5 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4013 6 at at IN cord-022526-j9kg00qf 4013 7 the the DT cord-022526-j9kg00qf 4013 8 recommended recommend VBN cord-022526-j9kg00qf 4013 9 dosage dosage NN cord-022526-j9kg00qf 4013 10 has have VBZ cord-022526-j9kg00qf 4013 11 been be VBN cord-022526-j9kg00qf 4013 12 reported report VBN cord-022526-j9kg00qf 4013 13 to to TO cord-022526-j9kg00qf 4013 14 cause cause VB cord-022526-j9kg00qf 4013 15 a a DT cord-022526-j9kg00qf 4013 16 significant significant JJ cord-022526-j9kg00qf 4013 17 decrease decrease NN cord-022526-j9kg00qf 4013 18 in in IN cord-022526-j9kg00qf 4013 19 plasma plasma NN cord-022526-j9kg00qf 4013 20 protein protein NN cord-022526-j9kg00qf 4013 21 concentration concentration NN cord-022526-j9kg00qf 4013 22 and and CC cord-022526-j9kg00qf 4013 23 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4013 24 disease disease NN cord-022526-j9kg00qf 4013 25 . . . cord-022526-j9kg00qf 4014 1 165 165 CD cord-022526-j9kg00qf 4014 2 , , , cord-022526-j9kg00qf 4014 3 170 170 CD cord-022526-j9kg00qf 4015 1 Moreover moreover RB cord-022526-j9kg00qf 4015 2 , , , cord-022526-j9kg00qf 4015 3 signs sign NNS cord-022526-j9kg00qf 4015 4 of of IN cord-022526-j9kg00qf 4015 5 NSAID NSAID NNP cord-022526-j9kg00qf 4015 6 toxicity toxicity NN cord-022526-j9kg00qf 4015 7 have have VBP cord-022526-j9kg00qf 4015 8 been be VBN cord-022526-j9kg00qf 4015 9 reported report VBN cord-022526-j9kg00qf 4015 10 in in IN cord-022526-j9kg00qf 4015 11 normovolemic normovolemic JJ cord-022526-j9kg00qf 4015 12 horses horse NNS cord-022526-j9kg00qf 4015 13 treated treat VBN cord-022526-j9kg00qf 4015 14 with with IN cord-022526-j9kg00qf 4015 15 appropriate appropriate JJ cord-022526-j9kg00qf 4015 16 doses dose NNS cord-022526-j9kg00qf 4015 17 of of IN cord-022526-j9kg00qf 4015 18 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4015 19 . . . cord-022526-j9kg00qf 4016 1 170 170 CD cord-022526-j9kg00qf 4016 2 , , , cord-022526-j9kg00qf 4016 3 171 171 CD cord-022526-j9kg00qf 4016 4 Dehydration dehydration NN cord-022526-j9kg00qf 4016 5 , , , cord-022526-j9kg00qf 4016 6 sepsis sepsis NN cord-022526-j9kg00qf 4016 7 , , , cord-022526-j9kg00qf 4016 8 and and CC cord-022526-j9kg00qf 4016 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4016 10 exacerbate exacerbate VBP cord-022526-j9kg00qf 4016 11 the the DT cord-022526-j9kg00qf 4016 12 renal renal JJ cord-022526-j9kg00qf 4016 13 and and CC cord-022526-j9kg00qf 4016 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4016 15 toxicity toxicity NN cord-022526-j9kg00qf 4016 16 of of IN cord-022526-j9kg00qf 4016 17 NSAIDs nsaid NNS cord-022526-j9kg00qf 4016 18 . . . cord-022526-j9kg00qf 4017 1 162 162 CD cord-022526-j9kg00qf 4018 1 Clearly clearly RB cord-022526-j9kg00qf 4018 2 , , , cord-022526-j9kg00qf 4018 3 the the DT cord-022526-j9kg00qf 4018 4 margin margin NN cord-022526-j9kg00qf 4018 5 of of IN cord-022526-j9kg00qf 4018 6 safety safety NN cord-022526-j9kg00qf 4018 7 is be VBZ cord-022526-j9kg00qf 4018 8 narrow narrow JJ cord-022526-j9kg00qf 4018 9 for for IN cord-022526-j9kg00qf 4018 10 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 4018 11 and and CC cord-022526-j9kg00qf 4018 12 probably probably RB cord-022526-j9kg00qf 4018 13 for for IN cord-022526-j9kg00qf 4018 14 other other JJ cord-022526-j9kg00qf 4018 15 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4018 16 used use VBN cord-022526-j9kg00qf 4018 17 in in IN cord-022526-j9kg00qf 4018 18 horses horse NNS cord-022526-j9kg00qf 4018 19 as as RB cord-022526-j9kg00qf 4018 20 well well RB cord-022526-j9kg00qf 4018 21 . . . cord-022526-j9kg00qf 4019 1 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4019 2 disease disease NN cord-022526-j9kg00qf 4019 3 induced induce VBN cord-022526-j9kg00qf 4019 4 by by IN cord-022526-j9kg00qf 4019 5 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4019 6 is be VBZ cord-022526-j9kg00qf 4019 7 manifested manifest VBN cord-022526-j9kg00qf 4019 8 by by IN cord-022526-j9kg00qf 4019 9 mucosal mucosal JJ cord-022526-j9kg00qf 4019 10 ulceration ulceration NN cord-022526-j9kg00qf 4019 11 , , , cord-022526-j9kg00qf 4019 12 inflammation inflammation NN cord-022526-j9kg00qf 4019 13 , , , cord-022526-j9kg00qf 4019 14 bleeding bleed VBG cord-022526-j9kg00qf 4019 15 , , , cord-022526-j9kg00qf 4019 16 and and CC cord-022526-j9kg00qf 4019 17 protein protein NN cord-022526-j9kg00qf 4019 18 - - HYPH cord-022526-j9kg00qf 4019 19 losing lose VBG cord-022526-j9kg00qf 4019 20 enteropathy enteropathy NNP cord-022526-j9kg00qf 4019 21 . . . cord-022526-j9kg00qf 4020 1 164 164 CD cord-022526-j9kg00qf 4020 2 , , , cord-022526-j9kg00qf 4020 3 165 165 CD cord-022526-j9kg00qf 4020 4 , , , cord-022526-j9kg00qf 4020 5 168 168 CD cord-022526-j9kg00qf 4020 6 , , , cord-022526-j9kg00qf 4020 7 170 170 CD cord-022526-j9kg00qf 4021 1 In in IN cord-022526-j9kg00qf 4021 2 addition addition NN cord-022526-j9kg00qf 4021 3 to to IN cord-022526-j9kg00qf 4021 4 direct direct JJ cord-022526-j9kg00qf 4021 5 effects effect NNS cord-022526-j9kg00qf 4021 6 on on IN cord-022526-j9kg00qf 4021 7 the the DT cord-022526-j9kg00qf 4021 8 mucosal mucosal JJ cord-022526-j9kg00qf 4021 9 barrier barrier NN cord-022526-j9kg00qf 4021 10 , , , cord-022526-j9kg00qf 4021 11 NSAID NSAID NNP cord-022526-j9kg00qf 4021 12 administration administration NN cord-022526-j9kg00qf 4021 13 has have VBZ cord-022526-j9kg00qf 4021 14 been be VBN cord-022526-j9kg00qf 4021 15 shown show VBN cord-022526-j9kg00qf 4021 16 to to TO cord-022526-j9kg00qf 4021 17 cause cause VB cord-022526-j9kg00qf 4021 18 an an DT cord-022526-j9kg00qf 4021 19 acute acute JJ cord-022526-j9kg00qf 4021 20 relapse relapse NN cord-022526-j9kg00qf 4021 21 of of IN cord-022526-j9kg00qf 4021 22 preexisting preexist VBG cord-022526-j9kg00qf 4021 23 colonic colonic JJ cord-022526-j9kg00qf 4021 24 inflammatory inflammatory JJ cord-022526-j9kg00qf 4021 25 disease disease NN cord-022526-j9kg00qf 4021 26 and and CC cord-022526-j9kg00qf 4021 27 worsen worsen VB cord-022526-j9kg00qf 4021 28 colonic colonic JJ cord-022526-j9kg00qf 4021 29 inflammation inflammation NN cord-022526-j9kg00qf 4021 30 in in IN cord-022526-j9kg00qf 4021 31 human human JJ cord-022526-j9kg00qf 4021 32 beings being NNS cord-022526-j9kg00qf 4021 33 . . . cord-022526-j9kg00qf 4022 1 164 164 CD cord-022526-j9kg00qf 4022 2 , , , cord-022526-j9kg00qf 4022 3 165 165 CD cord-022526-j9kg00qf 4022 4 , , , cord-022526-j9kg00qf 4022 5 170 170 CD cord-022526-j9kg00qf 4022 6 Whether whether IN cord-022526-j9kg00qf 4022 7 this this DT cord-022526-j9kg00qf 4022 8 occurs occur VBZ cord-022526-j9kg00qf 4022 9 in in IN cord-022526-j9kg00qf 4022 10 horses horse NNS cord-022526-j9kg00qf 4022 11 is be VBZ cord-022526-j9kg00qf 4022 12 not not RB cord-022526-j9kg00qf 4022 13 clear clear JJ cord-022526-j9kg00qf 4022 14 . . . cord-022526-j9kg00qf 4023 1 The the DT cord-022526-j9kg00qf 4023 2 mechanism mechanism NN cord-022526-j9kg00qf 4023 3 by by IN cord-022526-j9kg00qf 4023 4 which which WDT cord-022526-j9kg00qf 4023 5 NSAIDs nsaid NNS cord-022526-j9kg00qf 4023 6 induce induce VBP cord-022526-j9kg00qf 4023 7 mucosal mucosal JJ cord-022526-j9kg00qf 4023 8 damage damage NN cord-022526-j9kg00qf 4023 9 is be VBZ cord-022526-j9kg00qf 4023 10 probably probably RB cord-022526-j9kg00qf 4023 11 multifactorial multifactorial JJ cord-022526-j9kg00qf 4023 12 . . . cord-022526-j9kg00qf 4024 1 Direct direct JJ cord-022526-j9kg00qf 4024 2 irritation irritation NN cord-022526-j9kg00qf 4024 3 may may MD cord-022526-j9kg00qf 4024 4 play play VB cord-022526-j9kg00qf 4024 5 a a DT cord-022526-j9kg00qf 4024 6 role role NN cord-022526-j9kg00qf 4024 7 in in IN cord-022526-j9kg00qf 4024 8 oral oral JJ cord-022526-j9kg00qf 4024 9 and and CC cord-022526-j9kg00qf 4024 10 gastric gastric JJ cord-022526-j9kg00qf 4024 11 irritation irritation NN cord-022526-j9kg00qf 4024 12 and and CC cord-022526-j9kg00qf 4024 13 ulceration ulceration NN cord-022526-j9kg00qf 4024 14 ; ; : cord-022526-j9kg00qf 4024 15 however however RB cord-022526-j9kg00qf 4024 16 , , , cord-022526-j9kg00qf 4024 17 parenteral parenteral JJ cord-022526-j9kg00qf 4024 18 administration administration NN cord-022526-j9kg00qf 4024 19 of of IN cord-022526-j9kg00qf 4024 20 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4024 21 produces produce VBZ cord-022526-j9kg00qf 4024 22 oral oral JJ cord-022526-j9kg00qf 4024 23 and and CC cord-022526-j9kg00qf 4024 24 gastric gastric JJ cord-022526-j9kg00qf 4024 25 ulceration ulceration NN cord-022526-j9kg00qf 4024 26 as as RB cord-022526-j9kg00qf 4024 27 well well RB cord-022526-j9kg00qf 4024 28 . . . cord-022526-j9kg00qf 4025 1 Inhibition inhibition NN cord-022526-j9kg00qf 4025 2 of of IN cord-022526-j9kg00qf 4025 3 prostaglandin prostaglandin NN cord-022526-j9kg00qf 4025 4 synthesis synthesis NN cord-022526-j9kg00qf 4025 5 by by IN cord-022526-j9kg00qf 4025 6 inhibition inhibition NN cord-022526-j9kg00qf 4025 7 of of IN cord-022526-j9kg00qf 4025 8 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 4025 9 1 1 CD cord-022526-j9kg00qf 4025 10 ( ( -LRB- cord-022526-j9kg00qf 4025 11 the the DT cord-022526-j9kg00qf 4025 12 constitutive constitutive JJ cord-022526-j9kg00qf 4025 13 COX COX NNP cord-022526-j9kg00qf 4025 14 ) ) -RRB- cord-022526-j9kg00qf 4025 15 and and CC cord-022526-j9kg00qf 4025 16 cyclooxygenase cyclooxygenase JJ cord-022526-j9kg00qf 4025 17 2 2 CD cord-022526-j9kg00qf 4025 18 ( ( -LRB- cord-022526-j9kg00qf 4025 19 the the DT cord-022526-j9kg00qf 4025 20 inducible inducible JJ cord-022526-j9kg00qf 4025 21 COX COX NNP cord-022526-j9kg00qf 4025 22 ) ) -RRB- cord-022526-j9kg00qf 4025 23 appears appear VBZ cord-022526-j9kg00qf 4025 24 to to TO cord-022526-j9kg00qf 4025 25 be be VB cord-022526-j9kg00qf 4025 26 the the DT cord-022526-j9kg00qf 4025 27 most most RBS cord-022526-j9kg00qf 4025 28 important important JJ cord-022526-j9kg00qf 4025 29 mechanism mechanism NN cord-022526-j9kg00qf 4025 30 of of IN cord-022526-j9kg00qf 4025 31 mucosal mucosal JJ cord-022526-j9kg00qf 4025 32 injury injury NN cord-022526-j9kg00qf 4025 33 . . . cord-022526-j9kg00qf 4026 1 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4026 2 , , , cord-022526-j9kg00qf 4026 3 particularly particularly RB cord-022526-j9kg00qf 4026 4 PGE PGE NNP cord-022526-j9kg00qf 4026 5 2 2 CD cord-022526-j9kg00qf 4026 6 and and CC cord-022526-j9kg00qf 4026 7 PGI PGI NNP cord-022526-j9kg00qf 4026 8 2 2 CD cord-022526-j9kg00qf 4026 9 , , , cord-022526-j9kg00qf 4026 10 are be VBP cord-022526-j9kg00qf 4026 11 critical critical JJ cord-022526-j9kg00qf 4026 12 for for IN cord-022526-j9kg00qf 4026 13 mucosal mucosal JJ cord-022526-j9kg00qf 4026 14 health health NN cord-022526-j9kg00qf 4026 15 . . . cord-022526-j9kg00qf 4027 1 172,173 172,173 CD cord-022526-j9kg00qf 4027 2 PGE PGE NNP cord-022526-j9kg00qf 4027 3 2 2 CD cord-022526-j9kg00qf 4027 4 has have VBZ cord-022526-j9kg00qf 4027 5 been be VBN cord-022526-j9kg00qf 4027 6 shown show VBN cord-022526-j9kg00qf 4027 7 to to TO cord-022526-j9kg00qf 4027 8 increase increase VB cord-022526-j9kg00qf 4027 9 mucosal mucosal JJ cord-022526-j9kg00qf 4027 10 blood blood NN cord-022526-j9kg00qf 4027 11 flow flow NN cord-022526-j9kg00qf 4027 12 ; ; : cord-022526-j9kg00qf 4027 13 increase increase VBP cord-022526-j9kg00qf 4027 14 secretion secretion NN cord-022526-j9kg00qf 4027 15 of of IN cord-022526-j9kg00qf 4027 16 mucus mucus NN cord-022526-j9kg00qf 4027 17 , , , cord-022526-j9kg00qf 4027 18 water water NN cord-022526-j9kg00qf 4027 19 , , , cord-022526-j9kg00qf 4027 20 and and CC cord-022526-j9kg00qf 4027 21 bicarbonate bicarbonate NN cord-022526-j9kg00qf 4027 22 ; ; : cord-022526-j9kg00qf 4027 23 increase increase VB cord-022526-j9kg00qf 4027 24 mucosal mucosal JJ cord-022526-j9kg00qf 4027 25 cell cell NN cord-022526-j9kg00qf 4027 26 turnover turnover NN cord-022526-j9kg00qf 4027 27 rate rate NN cord-022526-j9kg00qf 4027 28 and and CC cord-022526-j9kg00qf 4027 29 migration migration NN cord-022526-j9kg00qf 4027 30 ; ; , cord-022526-j9kg00qf 4027 31 stimulate stimulate VB cord-022526-j9kg00qf 4027 32 adenyl adenyl NN cord-022526-j9kg00qf 4027 33 cyclase cyclase NN cord-022526-j9kg00qf 4027 34 activity activity NN cord-022526-j9kg00qf 4027 35 ; ; : cord-022526-j9kg00qf 4027 36 and and CC cord-022526-j9kg00qf 4027 37 exert exert VB cord-022526-j9kg00qf 4027 38 other other JJ cord-022526-j9kg00qf 4027 39 protective protective JJ cord-022526-j9kg00qf 4027 40 effects effect NNS cord-022526-j9kg00qf 4027 41 in in IN cord-022526-j9kg00qf 4027 42 the the DT cord-022526-j9kg00qf 4027 43 gastric gastric JJ cord-022526-j9kg00qf 4027 44 mucosa mucosa NN cord-022526-j9kg00qf 4027 45 of of IN cord-022526-j9kg00qf 4027 46 several several JJ cord-022526-j9kg00qf 4027 47 species specie NNS cord-022526-j9kg00qf 4027 48 . . . cord-022526-j9kg00qf 4028 1 162 162 CD cord-022526-j9kg00qf 4028 2 , , , cord-022526-j9kg00qf 4028 3 172 172 CD cord-022526-j9kg00qf 4028 4 , , , cord-022526-j9kg00qf 4028 5 173 173 CD cord-022526-j9kg00qf 4028 6 Perhaps perhaps RB cord-022526-j9kg00qf 4028 7 most most RBS cord-022526-j9kg00qf 4028 8 importantly importantly RB cord-022526-j9kg00qf 4028 9 , , , cord-022526-j9kg00qf 4028 10 PGE PGE NNP cord-022526-j9kg00qf 4028 11 2 2 CD cord-022526-j9kg00qf 4028 12 and and CC cord-022526-j9kg00qf 4028 13 PGI PGI NNP cord-022526-j9kg00qf 4028 14 2 2 CD cord-022526-j9kg00qf 4028 15 have have VBP cord-022526-j9kg00qf 4028 16 a a DT cord-022526-j9kg00qf 4028 17 role role NN cord-022526-j9kg00qf 4028 18 in in IN cord-022526-j9kg00qf 4028 19 maintaining maintain VBG cord-022526-j9kg00qf 4028 20 epithelial epithelial JJ cord-022526-j9kg00qf 4028 21 tight tight JJ cord-022526-j9kg00qf 4028 22 junction junction NN cord-022526-j9kg00qf 4028 23 integrity integrity NN cord-022526-j9kg00qf 4028 24 , , , cord-022526-j9kg00qf 4028 25 which which WDT cord-022526-j9kg00qf 4028 26 is be VBZ cord-022526-j9kg00qf 4028 27 indispensable indispensable JJ cord-022526-j9kg00qf 4028 28 for for IN cord-022526-j9kg00qf 4028 29 mucosal mucosal JJ cord-022526-j9kg00qf 4028 30 barrier barrier NN cord-022526-j9kg00qf 4028 31 function function NN cord-022526-j9kg00qf 4028 32 and and CC cord-022526-j9kg00qf 4028 33 repair repair NN cord-022526-j9kg00qf 4028 34 after after IN cord-022526-j9kg00qf 4028 35 mucosal mucosal JJ cord-022526-j9kg00qf 4028 36 injury injury NN cord-022526-j9kg00qf 4028 37 . . . cord-022526-j9kg00qf 4029 1 172 172 CD cord-022526-j9kg00qf 4030 1 In in IN cord-022526-j9kg00qf 4030 2 spite spite NN cord-022526-j9kg00qf 4030 3 of of IN cord-022526-j9kg00qf 4030 4 the the DT cord-022526-j9kg00qf 4030 5 overwhelming overwhelming JJ cord-022526-j9kg00qf 4030 6 amount amount NN cord-022526-j9kg00qf 4030 7 of of IN cord-022526-j9kg00qf 4030 8 information information NN cord-022526-j9kg00qf 4030 9 about about IN cord-022526-j9kg00qf 4030 10 the the DT cord-022526-j9kg00qf 4030 11 role role NN cord-022526-j9kg00qf 4030 12 of of IN cord-022526-j9kg00qf 4030 13 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4030 14 in in IN cord-022526-j9kg00qf 4030 15 maintaining maintain VBG cord-022526-j9kg00qf 4030 16 the the DT cord-022526-j9kg00qf 4030 17 mucosal mucosal JJ cord-022526-j9kg00qf 4030 18 barrier barrier NN cord-022526-j9kg00qf 4030 19 in in IN cord-022526-j9kg00qf 4030 20 other other JJ cord-022526-j9kg00qf 4030 21 species specie NNS cord-022526-j9kg00qf 4030 22 and and CC cord-022526-j9kg00qf 4030 23 clear clear JJ cord-022526-j9kg00qf 4030 24 clinical clinical JJ cord-022526-j9kg00qf 4030 25 and and CC cord-022526-j9kg00qf 4030 26 experimental experimental JJ cord-022526-j9kg00qf 4030 27 evidence evidence NN cord-022526-j9kg00qf 4030 28 that that IN cord-022526-j9kg00qf 4030 29 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4030 30 injure injure VB cord-022526-j9kg00qf 4030 31 the the DT cord-022526-j9kg00qf 4030 32 equine equine JJ cord-022526-j9kg00qf 4030 33 colonic colonic JJ cord-022526-j9kg00qf 4030 34 mucosa mucosa NN cord-022526-j9kg00qf 4030 35 , , , cord-022526-j9kg00qf 4030 36 the the DT cord-022526-j9kg00qf 4030 37 role role NN cord-022526-j9kg00qf 4030 38 of of IN cord-022526-j9kg00qf 4030 39 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4030 40 in in IN cord-022526-j9kg00qf 4030 41 mucosal mucosal JJ cord-022526-j9kg00qf 4030 42 protection protection NN cord-022526-j9kg00qf 4030 43 in in IN cord-022526-j9kg00qf 4030 44 the the DT cord-022526-j9kg00qf 4030 45 equine equine JJ cord-022526-j9kg00qf 4030 46 colon colon NN cord-022526-j9kg00qf 4030 47 is be VBZ cord-022526-j9kg00qf 4030 48 not not RB cord-022526-j9kg00qf 4030 49 yet yet RB cord-022526-j9kg00qf 4030 50 well well RB cord-022526-j9kg00qf 4030 51 defined define VBN cord-022526-j9kg00qf 4030 52 . . . cord-022526-j9kg00qf 4031 1 Inhibition inhibition NN cord-022526-j9kg00qf 4031 2 of of IN cord-022526-j9kg00qf 4031 3 COX-1 COX-1 NNP cord-022526-j9kg00qf 4031 4 and and CC cord-022526-j9kg00qf 4031 5 COX-2 COX-2 NNP cord-022526-j9kg00qf 4031 6 in in IN cord-022526-j9kg00qf 4031 7 equine equine JJ cord-022526-j9kg00qf 4031 8 colonic colonic JJ cord-022526-j9kg00qf 4031 9 mucosa mucosa NN cord-022526-j9kg00qf 4031 10 with with IN cord-022526-j9kg00qf 4031 11 flunixin flunixin NNP cord-022526-j9kg00qf 4031 12 meglumine meglumine NNP cord-022526-j9kg00qf 4031 13 resulted result VBD cord-022526-j9kg00qf 4031 14 in in IN cord-022526-j9kg00qf 4031 15 reduced reduce VBN cord-022526-j9kg00qf 4031 16 electric electric JJ cord-022526-j9kg00qf 4031 17 resistance resistance NN cord-022526-j9kg00qf 4031 18 of of IN cord-022526-j9kg00qf 4031 19 the the DT cord-022526-j9kg00qf 4031 20 mucosa mucosa JJ cord-022526-j9kg00qf 4031 21 and and CC cord-022526-j9kg00qf 4031 22 increased increase VBN cord-022526-j9kg00qf 4031 23 permeability permeability NN cord-022526-j9kg00qf 4031 24 to to IN cord-022526-j9kg00qf 4031 25 macromolecules macromolecule NNS cord-022526-j9kg00qf 4031 26 in in IN cord-022526-j9kg00qf 4031 27 vitro vitro FW cord-022526-j9kg00qf 4031 28 ( ( -LRB- cord-022526-j9kg00qf 4031 29 A.T. A.T. NNP cord-022526-j9kg00qf 4031 30 Blikslager Blikslager NNP cord-022526-j9kg00qf 4031 31 and and CC cord-022526-j9kg00qf 4031 32 S.L. S.L. NNP cord-022526-j9kg00qf 4031 33 Jones Jones NNP cord-022526-j9kg00qf 4031 34 , , , cord-022526-j9kg00qf 4031 35 2002 2002 CD cord-022526-j9kg00qf 4031 36 ) ) -RRB- cord-022526-j9kg00qf 4031 37 , , , cord-022526-j9kg00qf 4031 38 suggesting suggest VBG cord-022526-j9kg00qf 4031 39 that that IN cord-022526-j9kg00qf 4031 40 flunixin flunixin NNP cord-022526-j9kg00qf 4031 41 treatment treatment NN cord-022526-j9kg00qf 4031 42 disrupts disrupt VBZ cord-022526-j9kg00qf 4031 43 the the DT cord-022526-j9kg00qf 4031 44 epithelial epithelial JJ cord-022526-j9kg00qf 4031 45 tight tight JJ cord-022526-j9kg00qf 4031 46 junctions junction NNS cord-022526-j9kg00qf 4031 47 in in IN cord-022526-j9kg00qf 4031 48 the the DT cord-022526-j9kg00qf 4031 49 equine equine JJ cord-022526-j9kg00qf 4031 50 colon colon NN cord-022526-j9kg00qf 4031 51 . . . cord-022526-j9kg00qf 4032 1 Mucosal Mucosal NNP cord-022526-j9kg00qf 4032 2 changes change NNS cord-022526-j9kg00qf 4032 3 were be VBD cord-022526-j9kg00qf 4032 4 correlated correlate VBN cord-022526-j9kg00qf 4032 5 with with IN cord-022526-j9kg00qf 4032 6 a a DT cord-022526-j9kg00qf 4032 7 profound profound JJ cord-022526-j9kg00qf 4032 8 inhibition inhibition NN cord-022526-j9kg00qf 4032 9 of of IN cord-022526-j9kg00qf 4032 10 PGE PGE NNP cord-022526-j9kg00qf 4032 11 2 2 CD cord-022526-j9kg00qf 4032 12 and and CC cord-022526-j9kg00qf 4032 13 PGI PGI NNP cord-022526-j9kg00qf 4032 14 2 2 CD cord-022526-j9kg00qf 4032 15 concentrations concentration NNS cord-022526-j9kg00qf 4032 16 in in IN cord-022526-j9kg00qf 4032 17 the the DT cord-022526-j9kg00qf 4032 18 treated treat VBN cord-022526-j9kg00qf 4032 19 tissues tissue NNS cord-022526-j9kg00qf 4032 20 . . . cord-022526-j9kg00qf 4033 1 In in IN cord-022526-j9kg00qf 4033 2 other other JJ cord-022526-j9kg00qf 4033 3 studies study NNS cord-022526-j9kg00qf 4033 4 , , , cord-022526-j9kg00qf 4033 5 administration administration NN cord-022526-j9kg00qf 4033 6 of of IN cord-022526-j9kg00qf 4033 7 a a DT cord-022526-j9kg00qf 4033 8 PGE PGE NNP cord-022526-j9kg00qf 4033 9 2 2 CD cord-022526-j9kg00qf 4033 10 analog analog NN cord-022526-j9kg00qf 4033 11 prevented prevent VBD cord-022526-j9kg00qf 4033 12 the the DT cord-022526-j9kg00qf 4033 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4033 14 manifestations manifestation NNS cord-022526-j9kg00qf 4033 15 of of IN cord-022526-j9kg00qf 4033 16 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 4033 17 toxicosis toxicosis NN cord-022526-j9kg00qf 4033 18 in in IN cord-022526-j9kg00qf 4033 19 ponies pony NNS cord-022526-j9kg00qf 4033 20 . . . cord-022526-j9kg00qf 4034 1 165 165 CD cord-022526-j9kg00qf 4034 2 Recent recent JJ cord-022526-j9kg00qf 4034 3 development development NN cord-022526-j9kg00qf 4034 4 of of IN cord-022526-j9kg00qf 4034 5 NSAIDs nsaids JJ cord-022526-j9kg00qf 4034 6 specific specific JJ cord-022526-j9kg00qf 4034 7 for for IN cord-022526-j9kg00qf 4034 8 COX-2 COX-2 NNP cord-022526-j9kg00qf 4034 9 have have VBP cord-022526-j9kg00qf 4034 10 greatly greatly RB cord-022526-j9kg00qf 4034 11 reduced reduce VBN cord-022526-j9kg00qf 4034 12 the the DT cord-022526-j9kg00qf 4034 13 frequency frequency NN cord-022526-j9kg00qf 4034 14 and and CC cord-022526-j9kg00qf 4034 15 severity severity NN cord-022526-j9kg00qf 4034 16 of of IN cord-022526-j9kg00qf 4034 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4034 18 side side NN cord-022526-j9kg00qf 4034 19 effects effect NNS cord-022526-j9kg00qf 4034 20 in in IN cord-022526-j9kg00qf 4034 21 human human JJ cord-022526-j9kg00qf 4034 22 beings being NNS cord-022526-j9kg00qf 4034 23 taking take VBG cord-022526-j9kg00qf 4034 24 NSAIDs nsaid NNS cord-022526-j9kg00qf 4034 25 for for IN cord-022526-j9kg00qf 4034 26 chronic chronic JJ cord-022526-j9kg00qf 4034 27 musculoskeletal musculoskeletal JJ cord-022526-j9kg00qf 4034 28 conditions condition NNS cord-022526-j9kg00qf 4034 29 . . . cord-022526-j9kg00qf 4035 1 174 174 CD cord-022526-j9kg00qf 4036 1 Thus thus RB cord-022526-j9kg00qf 4037 1 COX-2-specific COX-2-specific NNP cord-022526-j9kg00qf 4037 2 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4037 3 hold hold VBP cord-022526-j9kg00qf 4037 4 promise promise NN cord-022526-j9kg00qf 4037 5 for for IN cord-022526-j9kg00qf 4037 6 use use NN cord-022526-j9kg00qf 4037 7 in in IN cord-022526-j9kg00qf 4037 8 horses horse NNS cord-022526-j9kg00qf 4037 9 to to TO cord-022526-j9kg00qf 4037 10 treat treat VB cord-022526-j9kg00qf 4037 11 arthritis arthritis NN cord-022526-j9kg00qf 4037 12 and and CC cord-022526-j9kg00qf 4037 13 reduce reduce VB cord-022526-j9kg00qf 4037 14 the the DT cord-022526-j9kg00qf 4037 15 incidence incidence NN cord-022526-j9kg00qf 4037 16 of of IN cord-022526-j9kg00qf 4037 17 toxicity toxicity NN cord-022526-j9kg00qf 4037 18 . . . cord-022526-j9kg00qf 4038 1 For for IN cord-022526-j9kg00qf 4038 2 example example NN cord-022526-j9kg00qf 4038 3 , , , cord-022526-j9kg00qf 4038 4 the the DT cord-022526-j9kg00qf 4038 5 COX-2-specific COX-2-specific NNP cord-022526-j9kg00qf 4038 6 inhibitor inhibitor NN cord-022526-j9kg00qf 4038 7 etodolac etodolac NNP cord-022526-j9kg00qf 4038 8 was be VBD cord-022526-j9kg00qf 4038 9 less less RBR cord-022526-j9kg00qf 4038 10 harmful harmful JJ cord-022526-j9kg00qf 4038 11 to to IN cord-022526-j9kg00qf 4038 12 equine equine JJ cord-022526-j9kg00qf 4038 13 colonic colonic JJ cord-022526-j9kg00qf 4038 14 mucosa mucosa NN cord-022526-j9kg00qf 4038 15 than than IN cord-022526-j9kg00qf 4038 16 flunixin flunixin NNP cord-022526-j9kg00qf 4038 17 meglumine meglumine NNP cord-022526-j9kg00qf 4038 18 in in FW cord-022526-j9kg00qf 4038 19 vitro vitro FW cord-022526-j9kg00qf 4038 20 ( ( -LRB- cord-022526-j9kg00qf 4038 21 A.T. A.T. NNP cord-022526-j9kg00qf 4038 22 Blikslager Blikslager NNP cord-022526-j9kg00qf 4038 23 and and CC cord-022526-j9kg00qf 4038 24 S.L. S.L. NNP cord-022526-j9kg00qf 4038 25 Jones Jones NNP cord-022526-j9kg00qf 4038 26 , , , cord-022526-j9kg00qf 4038 27 2002 2002 CD cord-022526-j9kg00qf 4038 28 ) ) -RRB- cord-022526-j9kg00qf 4038 29 . . . cord-022526-j9kg00qf 4039 1 Moreover moreover RB cord-022526-j9kg00qf 4039 2 , , , cord-022526-j9kg00qf 4039 3 etodolac etodolac NNP cord-022526-j9kg00qf 4039 4 was be VBD cord-022526-j9kg00qf 4039 5 significantly significantly RB cord-022526-j9kg00qf 4039 6 more more RBR cord-022526-j9kg00qf 4039 7 permissive permissive JJ cord-022526-j9kg00qf 4039 8 than than IN cord-022526-j9kg00qf 4039 9 flunixin flunixin NNP cord-022526-j9kg00qf 4039 10 for for IN cord-022526-j9kg00qf 4039 11 recovery recovery NN cord-022526-j9kg00qf 4039 12 of of IN cord-022526-j9kg00qf 4039 13 the the DT cord-022526-j9kg00qf 4039 14 mucosa mucosa NN cord-022526-j9kg00qf 4039 15 in in IN cord-022526-j9kg00qf 4039 16 equine equine JJ cord-022526-j9kg00qf 4039 17 ischemic ischemic JJ cord-022526-j9kg00qf 4039 18 - - HYPH cord-022526-j9kg00qf 4039 19 injured injured JJ cord-022526-j9kg00qf 4039 20 intestinal intestinal JJ cord-022526-j9kg00qf 4039 21 tissues tissue NNS cord-022526-j9kg00qf 4039 22 , , , cord-022526-j9kg00qf 4039 23 and and CC cord-022526-j9kg00qf 4039 24 in in IN cord-022526-j9kg00qf 4039 25 fact fact NN cord-022526-j9kg00qf 4039 26 , , , cord-022526-j9kg00qf 4039 27 recovery recovery NN cord-022526-j9kg00qf 4039 28 was be VBD cord-022526-j9kg00qf 4039 29 no no RB cord-022526-j9kg00qf 4039 30 different different JJ cord-022526-j9kg00qf 4039 31 than than IN cord-022526-j9kg00qf 4039 32 control control NN cord-022526-j9kg00qf 4039 33 tissues tissue NNS cord-022526-j9kg00qf 4039 34 . . . cord-022526-j9kg00qf 4040 1 175 175 CD cord-022526-j9kg00qf 4041 1 However however RB cord-022526-j9kg00qf 4041 2 , , , cord-022526-j9kg00qf 4041 3 their -PRON- PRP$ cord-022526-j9kg00qf 4041 4 use use NN cord-022526-j9kg00qf 4041 5 is be VBZ cord-022526-j9kg00qf 4041 6 at at IN cord-022526-j9kg00qf 4041 7 present present JJ cord-022526-j9kg00qf 4041 8 limited limit VBN cord-022526-j9kg00qf 4041 9 because because IN cord-022526-j9kg00qf 4041 10 the the DT cord-022526-j9kg00qf 4041 11 specificity specificity NN cord-022526-j9kg00qf 4041 12 of of IN cord-022526-j9kg00qf 4041 13 the the DT cord-022526-j9kg00qf 4041 14 so so RB cord-022526-j9kg00qf 4041 15 - - HYPH cord-022526-j9kg00qf 4041 16 called call VBN cord-022526-j9kg00qf 4041 17 COX-2selective cox-2selective JJ cord-022526-j9kg00qf 4041 18 inhibitors inhibitor NNS cord-022526-j9kg00qf 4041 19 and and CC cord-022526-j9kg00qf 4041 20 their -PRON- PRP$ cord-022526-j9kg00qf 4041 21 efficacy efficacy NN cord-022526-j9kg00qf 4041 22 as as IN cord-022526-j9kg00qf 4041 23 analgesics analgesic NNS cord-022526-j9kg00qf 4041 24 have have VBP cord-022526-j9kg00qf 4041 25 not not RB cord-022526-j9kg00qf 4041 26 been be VBN cord-022526-j9kg00qf 4041 27 demonstrated demonstrate VBN cord-022526-j9kg00qf 4041 28 in in IN cord-022526-j9kg00qf 4041 29 the the DT cord-022526-j9kg00qf 4041 30 horse horse NN cord-022526-j9kg00qf 4041 31 . . . cord-022526-j9kg00qf 4042 1 NSAID NSAID NNP cord-022526-j9kg00qf 4042 2 - - HYPH cord-022526-j9kg00qf 4042 3 induced induce VBN cord-022526-j9kg00qf 4042 4 mucosal mucosal JJ cord-022526-j9kg00qf 4042 5 injury injury NN cord-022526-j9kg00qf 4042 6 is be VBZ cord-022526-j9kg00qf 4042 7 associated associate VBN cord-022526-j9kg00qf 4042 8 with with IN cord-022526-j9kg00qf 4042 9 a a DT cord-022526-j9kg00qf 4042 10 significant significant JJ cord-022526-j9kg00qf 4042 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 4042 12 response response NN cord-022526-j9kg00qf 4042 13 to to IN cord-022526-j9kg00qf 4042 14 microbial microbial JJ cord-022526-j9kg00qf 4042 15 products product NNS cord-022526-j9kg00qf 4042 16 exposed expose VBN cord-022526-j9kg00qf 4042 17 to to IN cord-022526-j9kg00qf 4042 18 the the DT cord-022526-j9kg00qf 4042 19 lamina lamina JJ cord-022526-j9kg00qf 4042 20 propria propria NN cord-022526-j9kg00qf 4042 21 . . . cord-022526-j9kg00qf 4043 1 176 176 CD cord-022526-j9kg00qf 4044 1 This this DT cord-022526-j9kg00qf 4044 2 inflammation inflammation NN cord-022526-j9kg00qf 4044 3 exacerbates exacerbate VBZ cord-022526-j9kg00qf 4044 4 mucosal mucosal JJ cord-022526-j9kg00qf 4044 5 dysfunction dysfunction NN cord-022526-j9kg00qf 4044 6 and and CC cord-022526-j9kg00qf 4044 7 injury injury NN cord-022526-j9kg00qf 4044 8 associated associate VBN cord-022526-j9kg00qf 4044 9 with with IN cord-022526-j9kg00qf 4044 10 NSAID NSAID NNP cord-022526-j9kg00qf 4044 11 toxicity toxicity NN cord-022526-j9kg00qf 4044 12 . . . cord-022526-j9kg00qf 4045 1 For for IN cord-022526-j9kg00qf 4045 2 example example NN cord-022526-j9kg00qf 4045 3 , , , cord-022526-j9kg00qf 4045 4 depletion depletion NN cord-022526-j9kg00qf 4045 5 of of IN cord-022526-j9kg00qf 4045 6 neutrophils neutrophil NNS cord-022526-j9kg00qf 4045 7 or or CC cord-022526-j9kg00qf 4045 8 blockade blockade NN cord-022526-j9kg00qf 4045 9 of of IN cord-022526-j9kg00qf 4045 10 neutrophil neutrophil NN cord-022526-j9kg00qf 4045 11 influx influx NN cord-022526-j9kg00qf 4045 12 into into IN cord-022526-j9kg00qf 4045 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4045 14 tissues tissue NNS cord-022526-j9kg00qf 4045 15 or or CC cord-022526-j9kg00qf 4045 16 inhibition inhibition NN cord-022526-j9kg00qf 4045 17 of of IN cord-022526-j9kg00qf 4045 18 neutrophil neutrophil NN cord-022526-j9kg00qf 4045 19 activation activation NN cord-022526-j9kg00qf 4045 20 and and CC cord-022526-j9kg00qf 4045 21 release release NN cord-022526-j9kg00qf 4045 22 of of IN cord-022526-j9kg00qf 4045 23 toxic toxic JJ cord-022526-j9kg00qf 4045 24 products product NNS cord-022526-j9kg00qf 4045 25 prevents prevent VBZ cord-022526-j9kg00qf 4045 26 many many JJ cord-022526-j9kg00qf 4045 27 of of IN cord-022526-j9kg00qf 4045 28 the the DT cord-022526-j9kg00qf 4045 29 pathophysiologic pathophysiologic JJ cord-022526-j9kg00qf 4045 30 effects effect NNS cord-022526-j9kg00qf 4045 31 of of IN cord-022526-j9kg00qf 4045 32 NSAID NSAID NNP cord-022526-j9kg00qf 4045 33 toxicity toxicity NN cord-022526-j9kg00qf 4045 34 in in IN cord-022526-j9kg00qf 4045 35 the the DT cord-022526-j9kg00qf 4045 36 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4045 37 tract tract NN cord-022526-j9kg00qf 4045 38 . . . cord-022526-j9kg00qf 4046 1 [ [ -LRB- cord-022526-j9kg00qf 4046 2 177 177 CD cord-022526-j9kg00qf 4046 3 ] ] -RRB- cord-022526-j9kg00qf 4046 4 [ [ -LRB- cord-022526-j9kg00qf 4046 5 178 178 CD cord-022526-j9kg00qf 4046 6 ] ] -RRB- cord-022526-j9kg00qf 4046 7 [ [ -LRB- cord-022526-j9kg00qf 4046 8 179 179 CD cord-022526-j9kg00qf 4046 9 ] ] -RRB- cord-022526-j9kg00qf 4047 1 [ [ -LRB- cord-022526-j9kg00qf 4047 2 180 180 CD cord-022526-j9kg00qf 4047 3 ] ] -RRB- cord-022526-j9kg00qf 4048 1 The the DT cord-022526-j9kg00qf 4048 2 inflammatory inflammatory JJ cord-022526-j9kg00qf 4048 3 response response NN cord-022526-j9kg00qf 4048 4 alone alone RB cord-022526-j9kg00qf 4048 5 may may MD cord-022526-j9kg00qf 4048 6 result result VB cord-022526-j9kg00qf 4048 7 in in IN cord-022526-j9kg00qf 4048 8 moderate moderate JJ cord-022526-j9kg00qf 4048 9 to to TO cord-022526-j9kg00qf 4048 10 severe severe JJ cord-022526-j9kg00qf 4048 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4048 12 ulceration ulceration NN cord-022526-j9kg00qf 4048 13 , , , cord-022526-j9kg00qf 4048 14 mural mural JJ cord-022526-j9kg00qf 4048 15 vascular vascular JJ cord-022526-j9kg00qf 4048 16 thrombosis thrombosis NN cord-022526-j9kg00qf 4048 17 and and CC cord-022526-j9kg00qf 4048 18 edema edema NN cord-022526-j9kg00qf 4048 19 , , , cord-022526-j9kg00qf 4048 20 fluid fluid JJ cord-022526-j9kg00qf 4048 21 secretion secretion NN cord-022526-j9kg00qf 4048 22 , , , cord-022526-j9kg00qf 4048 23 protein protein NN cord-022526-j9kg00qf 4048 24 - - HYPH cord-022526-j9kg00qf 4048 25 losing lose VBG cord-022526-j9kg00qf 4048 26 enteropathy enteropathy NN cord-022526-j9kg00qf 4048 27 , , , cord-022526-j9kg00qf 4048 28 and and CC cord-022526-j9kg00qf 4048 29 mucosal mucosal JJ cord-022526-j9kg00qf 4048 30 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4048 31 . . . cord-022526-j9kg00qf 4049 1 NSAID NSAID NNP cord-022526-j9kg00qf 4049 2 colitis colitis NN cord-022526-j9kg00qf 4049 3 manifests manifest VBZ cord-022526-j9kg00qf 4049 4 as as IN cord-022526-j9kg00qf 4049 5 two two CD cord-022526-j9kg00qf 4049 6 clinical clinical JJ cord-022526-j9kg00qf 4049 7 syndromes syndrome NNS cord-022526-j9kg00qf 4049 8 : : : cord-022526-j9kg00qf 4049 9 right right JJ cord-022526-j9kg00qf 4049 10 dorsal dorsal JJ cord-022526-j9kg00qf 4049 11 colitis colitis NN cord-022526-j9kg00qf 4049 12 ( ( -LRB- cord-022526-j9kg00qf 4049 13 RDC RDC NNP cord-022526-j9kg00qf 4049 14 ) ) -RRB- cord-022526-j9kg00qf 4049 15 and and CC cord-022526-j9kg00qf 4049 16 generalized generalize VBD cord-022526-j9kg00qf 4049 17 NSAID NSAID NNP cord-022526-j9kg00qf 4049 18 toxicity toxicity NN cord-022526-j9kg00qf 4049 19 . . . cord-022526-j9kg00qf 4050 1 RDC RDC NNP cord-022526-j9kg00qf 4050 2 is be VBZ cord-022526-j9kg00qf 4050 3 an an DT cord-022526-j9kg00qf 4050 4 ulcerative ulcerative JJ cord-022526-j9kg00qf 4050 5 disorder disorder NN cord-022526-j9kg00qf 4050 6 isolated isolate VBN cord-022526-j9kg00qf 4050 7 to to IN cord-022526-j9kg00qf 4050 8 the the DT cord-022526-j9kg00qf 4050 9 right right JJ cord-022526-j9kg00qf 4050 10 dorsal dorsal JJ cord-022526-j9kg00qf 4050 11 segment segment NN cord-022526-j9kg00qf 4050 12 of of IN cord-022526-j9kg00qf 4050 13 the the DT cord-022526-j9kg00qf 4050 14 large large JJ cord-022526-j9kg00qf 4050 15 intestine intestine NN cord-022526-j9kg00qf 4050 16 . . . cord-022526-j9kg00qf 4051 1 167 167 CD cord-022526-j9kg00qf 4051 2 , , , cord-022526-j9kg00qf 4051 3 168 168 CD cord-022526-j9kg00qf 4051 4 , , , cord-022526-j9kg00qf 4051 5 171 171 CD cord-022526-j9kg00qf 4052 1 The the DT cord-022526-j9kg00qf 4052 2 most most RBS cord-022526-j9kg00qf 4052 3 prominent prominent JJ cord-022526-j9kg00qf 4052 4 clinical clinical JJ cord-022526-j9kg00qf 4052 5 signs sign NNS cord-022526-j9kg00qf 4052 6 of of IN cord-022526-j9kg00qf 4052 7 RDC RDC NNP cord-022526-j9kg00qf 4052 8 are be VBP cord-022526-j9kg00qf 4052 9 anorexia anorexia NN cord-022526-j9kg00qf 4052 10 , , , cord-022526-j9kg00qf 4052 11 lethargy lethargy NN cord-022526-j9kg00qf 4052 12 , , , cord-022526-j9kg00qf 4052 13 and and CC cord-022526-j9kg00qf 4052 14 colic colic NN cord-022526-j9kg00qf 4052 15 . . . cord-022526-j9kg00qf 4053 1 Anorexia anorexia NN cord-022526-j9kg00qf 4053 2 , , , cord-022526-j9kg00qf 4053 3 depression depression NN cord-022526-j9kg00qf 4053 4 , , , cord-022526-j9kg00qf 4053 5 diarrhea diarrhea NN cord-022526-j9kg00qf 4053 6 , , , cord-022526-j9kg00qf 4053 7 fever fever NN cord-022526-j9kg00qf 4053 8 , , , cord-022526-j9kg00qf 4053 9 and and CC cord-022526-j9kg00qf 4053 10 signs sign NNS cord-022526-j9kg00qf 4053 11 of of IN cord-022526-j9kg00qf 4053 12 SECTION section NN cord-022526-j9kg00qf 4053 13 13.13 13.13 CD cord-022526-j9kg00qf 4053 14 Inflammatory inflammatory JJ cord-022526-j9kg00qf 4053 15 Diseases disease NNS cord-022526-j9kg00qf 4053 16 of of IN cord-022526-j9kg00qf 4053 17 the the DT cord-022526-j9kg00qf 4053 18 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4053 19 Tract tract NN cord-022526-j9kg00qf 4053 20 Causing cause VBG cord-022526-j9kg00qf 4053 21 Diarrhea diarrhea NN cord-022526-j9kg00qf 4053 22 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4053 23 also also RB cord-022526-j9kg00qf 4053 24 may may MD cord-022526-j9kg00qf 4053 25 be be VB cord-022526-j9kg00qf 4053 26 features feature NNS cord-022526-j9kg00qf 4053 27 . . . cord-022526-j9kg00qf 4054 1 If if IN cord-022526-j9kg00qf 4054 2 the the DT cord-022526-j9kg00qf 4054 3 RDC RDC NNP cord-022526-j9kg00qf 4054 4 is be VBZ cord-022526-j9kg00qf 4054 5 chronic chronic JJ cord-022526-j9kg00qf 4054 6 , , , cord-022526-j9kg00qf 4054 7 weight weight NN cord-022526-j9kg00qf 4054 8 loss loss NN cord-022526-j9kg00qf 4054 9 , , , cord-022526-j9kg00qf 4054 10 intermittent intermittent JJ cord-022526-j9kg00qf 4054 11 colic colic NN cord-022526-j9kg00qf 4054 12 , , , cord-022526-j9kg00qf 4054 13 lethargy lethargy NN cord-022526-j9kg00qf 4054 14 , , , cord-022526-j9kg00qf 4054 15 anorexia anorexia NN cord-022526-j9kg00qf 4054 16 , , , cord-022526-j9kg00qf 4054 17 and and CC cord-022526-j9kg00qf 4054 18 ventral ventral JJ cord-022526-j9kg00qf 4054 19 edema edema NN cord-022526-j9kg00qf 4054 20 are be VBP cord-022526-j9kg00qf 4054 21 common common JJ cord-022526-j9kg00qf 4054 22 clinical clinical JJ cord-022526-j9kg00qf 4054 23 signs sign NNS cord-022526-j9kg00qf 4054 24 , , , cord-022526-j9kg00qf 4054 25 along along IN cord-022526-j9kg00qf 4054 26 with with IN cord-022526-j9kg00qf 4054 27 soft soft JJ cord-022526-j9kg00qf 4054 28 and and CC cord-022526-j9kg00qf 4054 29 unformed unformed JJ cord-022526-j9kg00qf 4054 30 feces fece NNS cord-022526-j9kg00qf 4054 31 . . . cord-022526-j9kg00qf 4055 1 Severe severe JJ cord-022526-j9kg00qf 4055 2 ulceration ulceration NN cord-022526-j9kg00qf 4055 3 of of IN cord-022526-j9kg00qf 4055 4 the the DT cord-022526-j9kg00qf 4055 5 right right JJ cord-022526-j9kg00qf 4055 6 dorsal dorsal JJ cord-022526-j9kg00qf 4055 7 colonic colonic JJ cord-022526-j9kg00qf 4055 8 mucosa mucosa NN cord-022526-j9kg00qf 4055 9 results result NNS cord-022526-j9kg00qf 4055 10 in in IN cord-022526-j9kg00qf 4055 11 proteinlosing proteinlose VBG cord-022526-j9kg00qf 4055 12 enteropathy enteropathy NNS cord-022526-j9kg00qf 4055 13 and and CC cord-022526-j9kg00qf 4055 14 significant significant JJ cord-022526-j9kg00qf 4055 15 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 4055 16 attributable attributable JJ cord-022526-j9kg00qf 4055 17 mainly mainly RB cord-022526-j9kg00qf 4055 18 to to IN cord-022526-j9kg00qf 4055 19 hypoalbuminemia hypoalbuminemia NNP cord-022526-j9kg00qf 4055 20 . . . cord-022526-j9kg00qf 4056 1 Hypoproteinemia Hypoproteinemia NNP cord-022526-j9kg00qf 4056 2 may may MD cord-022526-j9kg00qf 4056 3 be be VB cord-022526-j9kg00qf 4056 4 severe severe JJ cord-022526-j9kg00qf 4056 5 enough enough RB cord-022526-j9kg00qf 4056 6 to to TO cord-022526-j9kg00qf 4056 7 cause cause VB cord-022526-j9kg00qf 4056 8 peripheral peripheral JJ cord-022526-j9kg00qf 4056 9 ( ( -LRB- cord-022526-j9kg00qf 4056 10 usually usually RB cord-022526-j9kg00qf 4056 11 ventral ventral JJ cord-022526-j9kg00qf 4056 12 ) ) -RRB- cord-022526-j9kg00qf 4056 13 edema edema NN cord-022526-j9kg00qf 4056 14 . . . cord-022526-j9kg00qf 4057 1 In in IN cord-022526-j9kg00qf 4057 2 some some DT cord-022526-j9kg00qf 4057 3 cases case NNS cord-022526-j9kg00qf 4057 4 , , , cord-022526-j9kg00qf 4057 5 one one PRP cord-022526-j9kg00qf 4057 6 may may MD cord-022526-j9kg00qf 4057 7 note note VB cord-022526-j9kg00qf 4057 8 dehydration dehydration NN cord-022526-j9kg00qf 4057 9 , , , cord-022526-j9kg00qf 4057 10 electrolyte electrolyte JJ cord-022526-j9kg00qf 4057 11 abnormalities abnormality NNS cord-022526-j9kg00qf 4057 12 , , , cord-022526-j9kg00qf 4057 13 neutropenia neutropenia NN cord-022526-j9kg00qf 4057 14 or or CC cord-022526-j9kg00qf 4057 15 anemia anemia NN cord-022526-j9kg00qf 4057 16 , , , cord-022526-j9kg00qf 4057 17 azotemia azotemia NN cord-022526-j9kg00qf 4057 18 , , , cord-022526-j9kg00qf 4057 19 and and CC cord-022526-j9kg00qf 4057 20 biochemical biochemical JJ cord-022526-j9kg00qf 4057 21 abnormalities abnormality NNS cord-022526-j9kg00qf 4057 22 if if IN cord-022526-j9kg00qf 4057 23 the the DT cord-022526-j9kg00qf 4057 24 ulceration ulceration NN cord-022526-j9kg00qf 4057 25 and and CC cord-022526-j9kg00qf 4057 26 diarrhea diarrhea NN cord-022526-j9kg00qf 4057 27 are be VBP cord-022526-j9kg00qf 4057 28 severe severe JJ cord-022526-j9kg00qf 4057 29 or or CC cord-022526-j9kg00qf 4057 30 if if IN cord-022526-j9kg00qf 4057 31 systemic systemic JJ cord-022526-j9kg00qf 4057 32 inflammation inflammation NN cord-022526-j9kg00qf 4057 33 is be VBZ cord-022526-j9kg00qf 4057 34 present present JJ cord-022526-j9kg00qf 4057 35 . . . cord-022526-j9kg00qf 4058 1 Clinical clinical JJ cord-022526-j9kg00qf 4058 2 signs sign NNS cord-022526-j9kg00qf 4058 3 of of IN cord-022526-j9kg00qf 4058 4 generalized generalize VBN cord-022526-j9kg00qf 4058 5 NSAID NSAID NNP cord-022526-j9kg00qf 4058 6 toxicity toxicity NN cord-022526-j9kg00qf 4058 7 may may MD cord-022526-j9kg00qf 4058 8 vary vary VB cord-022526-j9kg00qf 4058 9 from from IN cord-022526-j9kg00qf 4058 10 mild mild JJ cord-022526-j9kg00qf 4058 11 diarrhea diarrhea NN cord-022526-j9kg00qf 4058 12 with with IN cord-022526-j9kg00qf 4058 13 no no DT cord-022526-j9kg00qf 4058 14 systemic systemic JJ cord-022526-j9kg00qf 4058 15 signs sign NNS cord-022526-j9kg00qf 4058 16 to to IN cord-022526-j9kg00qf 4058 17 severe severe JJ cord-022526-j9kg00qf 4058 18 dehydrating dehydrate VBG cord-022526-j9kg00qf 4058 19 diarrhea diarrhea NN cord-022526-j9kg00qf 4058 20 with with IN cord-022526-j9kg00qf 4058 21 anorexia anorexia NN cord-022526-j9kg00qf 4058 22 , , , cord-022526-j9kg00qf 4058 23 fever fever NN cord-022526-j9kg00qf 4058 24 , , , cord-022526-j9kg00qf 4058 25 depression depression NN cord-022526-j9kg00qf 4058 26 , , , cord-022526-j9kg00qf 4058 27 peripheral peripheral JJ cord-022526-j9kg00qf 4058 28 edema edema NN cord-022526-j9kg00qf 4058 29 , , , cord-022526-j9kg00qf 4058 30 oral oral JJ cord-022526-j9kg00qf 4058 31 ulceration ulceration NN cord-022526-j9kg00qf 4058 32 , , , cord-022526-j9kg00qf 4058 33 and and CC cord-022526-j9kg00qf 4058 34 colic colic NN cord-022526-j9kg00qf 4058 35 . . . cord-022526-j9kg00qf 4059 1 165 165 CD cord-022526-j9kg00qf 4059 2 , , , cord-022526-j9kg00qf 4059 3 166 166 CD cord-022526-j9kg00qf 4059 4 , , , cord-022526-j9kg00qf 4059 5 169 169 CD cord-022526-j9kg00qf 4059 6 Clinical clinical JJ cord-022526-j9kg00qf 4059 7 signs sign NNS cord-022526-j9kg00qf 4059 8 of of IN cord-022526-j9kg00qf 4059 9 systemic systemic JJ cord-022526-j9kg00qf 4059 10 inflammation inflammation NN cord-022526-j9kg00qf 4059 11 caused cause VBN cord-022526-j9kg00qf 4059 12 by by IN cord-022526-j9kg00qf 4059 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4059 14 may may MD cord-022526-j9kg00qf 4059 15 occur occur VB cord-022526-j9kg00qf 4059 16 , , , cord-022526-j9kg00qf 4059 17 manifested manifest VBN cord-022526-j9kg00qf 4059 18 as as IN cord-022526-j9kg00qf 4059 19 poor poor JJ cord-022526-j9kg00qf 4059 20 peripheral peripheral JJ cord-022526-j9kg00qf 4059 21 perfusion perfusion NN cord-022526-j9kg00qf 4059 22 , , , cord-022526-j9kg00qf 4059 23 tachycardia tachycardia NN cord-022526-j9kg00qf 4059 24 , , , cord-022526-j9kg00qf 4059 25 tachypnea tachypnea NNP cord-022526-j9kg00qf 4059 26 , , , cord-022526-j9kg00qf 4059 27 weakness weakness NN cord-022526-j9kg00qf 4059 28 , , , cord-022526-j9kg00qf 4059 29 trembling tremble VBG cord-022526-j9kg00qf 4059 30 , , , cord-022526-j9kg00qf 4059 31 and and CC cord-022526-j9kg00qf 4059 32 cyanotic cyanotic JJ cord-022526-j9kg00qf 4059 33 or or CC cord-022526-j9kg00qf 4059 34 hyperemic hyperemic JJ cord-022526-j9kg00qf 4059 35 oral oral JJ cord-022526-j9kg00qf 4059 36 mucous mucous JJ cord-022526-j9kg00qf 4059 37 membranes membrane NNS cord-022526-j9kg00qf 4059 38 . . . cord-022526-j9kg00qf 4060 1 Hematuria Hematuria NNP cord-022526-j9kg00qf 4060 2 or or CC cord-022526-j9kg00qf 4060 3 oliguria oliguria NNP cord-022526-j9kg00qf 4060 4 may may MD cord-022526-j9kg00qf 4060 5 be be VB cord-022526-j9kg00qf 4060 6 present present JJ cord-022526-j9kg00qf 4060 7 if if IN cord-022526-j9kg00qf 4060 8 renal renal JJ cord-022526-j9kg00qf 4060 9 involvement involvement NN cord-022526-j9kg00qf 4060 10 is be VBZ cord-022526-j9kg00qf 4060 11 present present JJ cord-022526-j9kg00qf 4060 12 . . . cord-022526-j9kg00qf 4061 1 Complications complication NNS cord-022526-j9kg00qf 4061 2 associated associate VBN cord-022526-j9kg00qf 4061 3 with with IN cord-022526-j9kg00qf 4061 4 other other JJ cord-022526-j9kg00qf 4061 5 forms form NNS cord-022526-j9kg00qf 4061 6 of of IN cord-022526-j9kg00qf 4061 7 severe severe JJ cord-022526-j9kg00qf 4061 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4061 9 , , , cord-022526-j9kg00qf 4061 10 such such JJ cord-022526-j9kg00qf 4061 11 as as IN cord-022526-j9kg00qf 4061 12 laminitis laminitis NN cord-022526-j9kg00qf 4061 13 , , , cord-022526-j9kg00qf 4061 14 thrombophlebitis thrombophlebitis NNP cord-022526-j9kg00qf 4061 15 , , , cord-022526-j9kg00qf 4061 16 and and CC cord-022526-j9kg00qf 4061 17 severe severe JJ cord-022526-j9kg00qf 4061 18 weight weight NN cord-022526-j9kg00qf 4061 19 loss loss NN cord-022526-j9kg00qf 4061 20 , , , cord-022526-j9kg00qf 4061 21 may may MD cord-022526-j9kg00qf 4061 22 occur occur VB cord-022526-j9kg00qf 4061 23 . . . cord-022526-j9kg00qf 4062 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 4062 2 abnormalities abnormality NNS cord-022526-j9kg00qf 4062 3 of of IN cord-022526-j9kg00qf 4062 4 generalized generalize VBN cord-022526-j9kg00qf 4062 5 NSAID NSAID NNP cord-022526-j9kg00qf 4062 6 toxicity toxicity NN cord-022526-j9kg00qf 4062 7 are be VBP cord-022526-j9kg00qf 4062 8 nonspecific nonspecific JJ cord-022526-j9kg00qf 4062 9 and and CC cord-022526-j9kg00qf 4062 10 include include VBP cord-022526-j9kg00qf 4062 11 neutropenia neutropenia NN cord-022526-j9kg00qf 4062 12 with with IN cord-022526-j9kg00qf 4062 13 a a DT cord-022526-j9kg00qf 4062 14 left left JJ cord-022526-j9kg00qf 4062 15 shift shift NN cord-022526-j9kg00qf 4062 16 or or CC cord-022526-j9kg00qf 4062 17 leukocytosis leukocytosis NN cord-022526-j9kg00qf 4062 18 and and CC cord-022526-j9kg00qf 4062 19 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 4062 20 . . . cord-022526-j9kg00qf 4063 1 Serum serum NN cord-022526-j9kg00qf 4063 2 biochemical biochemical JJ cord-022526-j9kg00qf 4063 3 analysis analysis NN cord-022526-j9kg00qf 4063 4 is be VBZ cord-022526-j9kg00qf 4063 5 characterized characterize VBN cord-022526-j9kg00qf 4063 6 by by IN cord-022526-j9kg00qf 4063 7 profound profound JJ cord-022526-j9kg00qf 4063 8 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 4063 9 , , , cord-022526-j9kg00qf 4063 10 hyponatremia hyponatremia NN cord-022526-j9kg00qf 4063 11 , , , cord-022526-j9kg00qf 4063 12 and and CC cord-022526-j9kg00qf 4063 13 metabolic metabolic JJ cord-022526-j9kg00qf 4063 14 acidosis acidosis NN cord-022526-j9kg00qf 4063 15 . . . cord-022526-j9kg00qf 4064 1 169 169 CD cord-022526-j9kg00qf 4064 2 , , , cord-022526-j9kg00qf 4064 3 170 170 CD cord-022526-j9kg00qf 4064 4 Hypocalcemia Hypocalcemia NNP cord-022526-j9kg00qf 4064 5 , , , cord-022526-j9kg00qf 4064 6 hypokalemia hypokalemia NN cord-022526-j9kg00qf 4064 7 , , , cord-022526-j9kg00qf 4064 8 hypochloremia hypochloremia NN cord-022526-j9kg00qf 4064 9 , , , cord-022526-j9kg00qf 4064 10 and and CC cord-022526-j9kg00qf 4064 11 elevated elevated JJ cord-022526-j9kg00qf 4064 12 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 4064 13 enzyme enzyme NN cord-022526-j9kg00qf 4064 14 activities activity NNS cord-022526-j9kg00qf 4064 15 also also RB cord-022526-j9kg00qf 4064 16 may may MD cord-022526-j9kg00qf 4064 17 occur occur VB cord-022526-j9kg00qf 4064 18 . . . cord-022526-j9kg00qf 4065 1 Hypoproteinemia Hypoproteinemia NNP cord-022526-j9kg00qf 4065 2 may may MD cord-022526-j9kg00qf 4065 3 occur occur VB cord-022526-j9kg00qf 4065 4 without without IN cord-022526-j9kg00qf 4065 5 signs sign NNS cord-022526-j9kg00qf 4065 6 of of IN cord-022526-j9kg00qf 4065 7 diarrhea diarrhea NN cord-022526-j9kg00qf 4065 8 . . . cord-022526-j9kg00qf 4066 1 Azotemia Azotemia NNP cord-022526-j9kg00qf 4066 2 may may MD cord-022526-j9kg00qf 4066 3 be be VB cord-022526-j9kg00qf 4066 4 prerenal prerenal JJ cord-022526-j9kg00qf 4066 5 from from IN cord-022526-j9kg00qf 4066 6 dehydration dehydration NN cord-022526-j9kg00qf 4066 7 but but CC cord-022526-j9kg00qf 4066 8 frequently frequently RB cord-022526-j9kg00qf 4066 9 is be VBZ cord-022526-j9kg00qf 4066 10 caused cause VBN cord-022526-j9kg00qf 4066 11 by by IN cord-022526-j9kg00qf 4066 12 renal renal JJ cord-022526-j9kg00qf 4066 13 failure failure NN cord-022526-j9kg00qf 4066 14 resulting result VBG cord-022526-j9kg00qf 4066 15 from from IN cord-022526-j9kg00qf 4066 16 a a DT cord-022526-j9kg00qf 4066 17 combination combination NN cord-022526-j9kg00qf 4066 18 of of IN cord-022526-j9kg00qf 4066 19 hemodynamic hemodynamic JJ cord-022526-j9kg00qf 4066 20 and and CC cord-022526-j9kg00qf 4066 21 toxic toxic JJ cord-022526-j9kg00qf 4066 22 renal renal JJ cord-022526-j9kg00qf 4066 23 injury injury NN cord-022526-j9kg00qf 4066 24 . . . cord-022526-j9kg00qf 4067 1 Urinalysis urinalysis NN cord-022526-j9kg00qf 4067 2 frequently frequently RB cord-022526-j9kg00qf 4067 3 reveals reveal VBZ cord-022526-j9kg00qf 4067 4 hematuria hematuria NN cord-022526-j9kg00qf 4067 5 , , , cord-022526-j9kg00qf 4067 6 proteinuria proteinuria NN cord-022526-j9kg00qf 4067 7 , , , cord-022526-j9kg00qf 4067 8 cylindruria cylindruria NNP cord-022526-j9kg00qf 4067 9 , , , cord-022526-j9kg00qf 4067 10 and and CC cord-022526-j9kg00qf 4067 11 isosthenuria isosthenuria NNP cord-022526-j9kg00qf 4067 12 . . . cord-022526-j9kg00qf 4068 1 Fecal fecal JJ cord-022526-j9kg00qf 4068 2 occult occult JJ cord-022526-j9kg00qf 4068 3 blood blood NN cord-022526-j9kg00qf 4068 4 is be VBZ cord-022526-j9kg00qf 4068 5 frequently frequently RB cord-022526-j9kg00qf 4068 6 detectable detectable JJ cord-022526-j9kg00qf 4068 7 . . . cord-022526-j9kg00qf 4069 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 4069 2 of of IN cord-022526-j9kg00qf 4069 3 either either DT cord-022526-j9kg00qf 4069 4 form form NN cord-022526-j9kg00qf 4069 5 of of IN cord-022526-j9kg00qf 4069 6 NSAID NSAID NNP cord-022526-j9kg00qf 4069 7 colitis colitis NN cord-022526-j9kg00qf 4069 8 is be VBZ cord-022526-j9kg00qf 4069 9 often often RB cord-022526-j9kg00qf 4069 10 presumptive presumptive JJ cord-022526-j9kg00qf 4069 11 , , , cord-022526-j9kg00qf 4069 12 with with IN cord-022526-j9kg00qf 4069 13 a a DT cord-022526-j9kg00qf 4069 14 history history NN cord-022526-j9kg00qf 4069 15 of of IN cord-022526-j9kg00qf 4069 16 overdose overdose NN cord-022526-j9kg00qf 4069 17 of of IN cord-022526-j9kg00qf 4069 18 NSAIDs nsaid NNS cord-022526-j9kg00qf 4069 19 being be VBG cord-022526-j9kg00qf 4069 20 strong strong JJ cord-022526-j9kg00qf 4069 21 evidence evidence NN cord-022526-j9kg00qf 4069 22 of of IN cord-022526-j9kg00qf 4069 23 NSAID NSAID NNP cord-022526-j9kg00qf 4069 24 toxicity toxicity NN cord-022526-j9kg00qf 4069 25 . . . cord-022526-j9kg00qf 4070 1 But but CC cord-022526-j9kg00qf 4070 2 as as IN cord-022526-j9kg00qf 4070 3 discussed discuss VBN cord-022526-j9kg00qf 4070 4 earlier early RBR cord-022526-j9kg00qf 4070 5 , , , cord-022526-j9kg00qf 4070 6 toxicity toxicity NN cord-022526-j9kg00qf 4070 7 may may MD cord-022526-j9kg00qf 4070 8 occur occur VB cord-022526-j9kg00qf 4070 9 with with IN cord-022526-j9kg00qf 4070 10 dosage dosage NN cord-022526-j9kg00qf 4070 11 regimens regimen NNS cord-022526-j9kg00qf 4070 12 that that WDT cord-022526-j9kg00qf 4070 13 are be VBP cord-022526-j9kg00qf 4070 14 not not RB cord-022526-j9kg00qf 4070 15 considered consider VBN cord-022526-j9kg00qf 4070 16 inappropriate inappropriate JJ cord-022526-j9kg00qf 4070 17 , , , cord-022526-j9kg00qf 4070 18 particularly particularly RB cord-022526-j9kg00qf 4070 19 if if IN cord-022526-j9kg00qf 4070 20 the the DT cord-022526-j9kg00qf 4070 21 horse horse NN cord-022526-j9kg00qf 4070 22 experiences experience VBZ cord-022526-j9kg00qf 4070 23 a a DT cord-022526-j9kg00qf 4070 24 concurrent concurrent JJ cord-022526-j9kg00qf 4070 25 period period NN cord-022526-j9kg00qf 4070 26 of of IN cord-022526-j9kg00qf 4070 27 dehydration dehydration NN cord-022526-j9kg00qf 4070 28 . . . cord-022526-j9kg00qf 4071 1 One one PRP cord-022526-j9kg00qf 4071 2 can can MD cord-022526-j9kg00qf 4071 3 use use VB cord-022526-j9kg00qf 4071 4 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 4071 5 examination examination NN cord-022526-j9kg00qf 4071 6 of of IN cord-022526-j9kg00qf 4071 7 the the DT cord-022526-j9kg00qf 4071 8 right right JJ cord-022526-j9kg00qf 4071 9 dorsal dorsal JJ cord-022526-j9kg00qf 4071 10 colon colon NN cord-022526-j9kg00qf 4071 11 to to TO cord-022526-j9kg00qf 4071 12 confirm confirm VB cord-022526-j9kg00qf 4071 13 a a DT cord-022526-j9kg00qf 4071 14 diagnosis diagnosis NN cord-022526-j9kg00qf 4071 15 of of IN cord-022526-j9kg00qf 4071 16 RDC RDC NNP cord-022526-j9kg00qf 4071 17 , , , cord-022526-j9kg00qf 4071 18 but but CC cord-022526-j9kg00qf 4071 19 the the DT cord-022526-j9kg00qf 4071 20 sensitivity sensitivity NN cord-022526-j9kg00qf 4071 21 of of IN cord-022526-j9kg00qf 4071 22 this this DT cord-022526-j9kg00qf 4071 23 method method NN cord-022526-j9kg00qf 4071 24 is be VBZ cord-022526-j9kg00qf 4071 25 questionable questionable JJ cord-022526-j9kg00qf 4071 26 . . . cord-022526-j9kg00qf 4072 1 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 4072 2 ( ( -LRB- cord-022526-j9kg00qf 4072 3 3.5-to 3.5-to CD cord-022526-j9kg00qf 4072 4 5-MHz 5-mhz CD cord-022526-j9kg00qf 4072 5 transducer transducer NN cord-022526-j9kg00qf 4072 6 at at IN cord-022526-j9kg00qf 4072 7 the the DT cord-022526-j9kg00qf 4072 8 right right JJ cord-022526-j9kg00qf 4072 9 twelfth twelfth JJ cord-022526-j9kg00qf 4072 10 to to IN cord-022526-j9kg00qf 4072 11 fifteenth fifteenth JJ cord-022526-j9kg00qf 4072 12 intercostal intercostal JJ cord-022526-j9kg00qf 4072 13 spaces space NNS cord-022526-j9kg00qf 4072 14 below below IN cord-022526-j9kg00qf 4072 15 the the DT cord-022526-j9kg00qf 4072 16 margin margin NN cord-022526-j9kg00qf 4072 17 of of IN cord-022526-j9kg00qf 4072 18 the the DT cord-022526-j9kg00qf 4072 19 lung lung NN cord-022526-j9kg00qf 4072 20 axial axial NN cord-022526-j9kg00qf 4072 21 to to IN cord-022526-j9kg00qf 4072 22 the the DT cord-022526-j9kg00qf 4072 23 liver liver NN cord-022526-j9kg00qf 4072 24 ) ) -RRB- cord-022526-j9kg00qf 4072 25 may may MD cord-022526-j9kg00qf 4072 26 reveal reveal VB cord-022526-j9kg00qf 4072 27 a a DT cord-022526-j9kg00qf 4072 28 thickened thickened JJ cord-022526-j9kg00qf 4072 29 right right JJ cord-022526-j9kg00qf 4072 30 dorsal dorsal JJ cord-022526-j9kg00qf 4072 31 colon colon NN cord-022526-j9kg00qf 4072 32 ( ( -LRB- cord-022526-j9kg00qf 4072 33 > > NFP cord-022526-j9kg00qf 4072 34 0.5 0.5 CD cord-022526-j9kg00qf 4072 35 cm cm NNS cord-022526-j9kg00qf 4072 36 ) ) -RRB- cord-022526-j9kg00qf 4072 37 and and CC cord-022526-j9kg00qf 4072 38 evidence evidence NN cord-022526-j9kg00qf 4072 39 of of IN cord-022526-j9kg00qf 4072 40 colonic colonic JJ cord-022526-j9kg00qf 4072 41 edema edema NN cord-022526-j9kg00qf 4072 42 in in IN cord-022526-j9kg00qf 4072 43 horses horse NNS cord-022526-j9kg00qf 4072 44 with with IN cord-022526-j9kg00qf 4072 45 RDC RDC NNP cord-022526-j9kg00qf 4072 46 . . . cord-022526-j9kg00qf 4073 1 181 181 CD cord-022526-j9kg00qf 4074 1 However however RB cord-022526-j9kg00qf 4074 2 , , , cord-022526-j9kg00qf 4074 3 the the DT cord-022526-j9kg00qf 4074 4 sensitivity sensitivity NN cord-022526-j9kg00qf 4074 5 of of IN cord-022526-j9kg00qf 4074 6 this this DT cord-022526-j9kg00qf 4074 7 method method NN cord-022526-j9kg00qf 4074 8 of of IN cord-022526-j9kg00qf 4074 9 diagnosis diagnosis NN cord-022526-j9kg00qf 4074 10 is be VBZ cord-022526-j9kg00qf 4074 11 questionable questionable JJ cord-022526-j9kg00qf 4074 12 . . . cord-022526-j9kg00qf 4075 1 One one PRP cord-022526-j9kg00qf 4075 2 can can MD cord-022526-j9kg00qf 4075 3 use use VB cord-022526-j9kg00qf 4075 4 nuclear nuclear JJ cord-022526-j9kg00qf 4075 5 scintigraphy scintigraphy NN cord-022526-j9kg00qf 4075 6 of of IN cord-022526-j9kg00qf 4075 7 horses horse NNS cord-022526-j9kg00qf 4075 8 after after IN cord-022526-j9kg00qf 4075 9 infusion infusion NN cord-022526-j9kg00qf 4075 10 with with IN cord-022526-j9kg00qf 4075 11 technetium technetium NN cord-022526-j9kg00qf 4075 12 99-labeled 99-labeled CD cord-022526-j9kg00qf 4075 13 white white JJ cord-022526-j9kg00qf 4075 14 blood blood NN cord-022526-j9kg00qf 4075 15 cells cell NNS cord-022526-j9kg00qf 4075 16 to to IN cord-022526-j9kg00qf 4075 17 document document NN cord-022526-j9kg00qf 4075 18 inflammation inflammation NN cord-022526-j9kg00qf 4075 19 of of IN cord-022526-j9kg00qf 4075 20 the the DT cord-022526-j9kg00qf 4075 21 right right JJ cord-022526-j9kg00qf 4075 22 dorsal dorsal JJ cord-022526-j9kg00qf 4075 23 colon colon NN cord-022526-j9kg00qf 4075 24 . . . cord-022526-j9kg00qf 4076 1 182 182 CD cord-022526-j9kg00qf 4076 2 Diagnosis Diagnosis NNP cord-022526-j9kg00qf 4076 3 of of IN cord-022526-j9kg00qf 4076 4 RDC RDC NNP cord-022526-j9kg00qf 4076 5 may may MD cord-022526-j9kg00qf 4076 6 require require VB cord-022526-j9kg00qf 4076 7 one one CD cord-022526-j9kg00qf 4076 8 to to TO cord-022526-j9kg00qf 4076 9 perform perform VB cord-022526-j9kg00qf 4076 10 laparotomy laparotomy NN cord-022526-j9kg00qf 4076 11 or or CC cord-022526-j9kg00qf 4076 12 laparoscopic laparoscopic JJ cord-022526-j9kg00qf 4076 13 examination examination NN cord-022526-j9kg00qf 4076 14 of of IN cord-022526-j9kg00qf 4076 15 the the DT cord-022526-j9kg00qf 4076 16 right right JJ cord-022526-j9kg00qf 4076 17 dorsal dorsal JJ cord-022526-j9kg00qf 4076 18 colon colon NN cord-022526-j9kg00qf 4076 19 . . . cord-022526-j9kg00qf 4077 1 One one PRP cord-022526-j9kg00qf 4077 2 must must MD cord-022526-j9kg00qf 4077 3 rule rule VB cord-022526-j9kg00qf 4077 4 out out RP cord-022526-j9kg00qf 4077 5 other other JJ cord-022526-j9kg00qf 4077 6 causes cause NNS cord-022526-j9kg00qf 4077 7 of of IN cord-022526-j9kg00qf 4077 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4077 9 , , , cord-022526-j9kg00qf 4077 10 such such JJ cord-022526-j9kg00qf 4077 11 as as IN cord-022526-j9kg00qf 4077 12 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4077 13 , , , cord-022526-j9kg00qf 4077 14 Potomac Potomac NNP cord-022526-j9kg00qf 4077 15 horse horse NN cord-022526-j9kg00qf 4077 16 fever fever NN cord-022526-j9kg00qf 4077 17 , , , cord-022526-j9kg00qf 4077 18 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4077 19 , , , cord-022526-j9kg00qf 4077 20 and and CC cord-022526-j9kg00qf 4077 21 antibiotic antibiotic NN cord-022526-j9kg00qf 4077 22 - - HYPH cord-022526-j9kg00qf 4077 23 associated associated JJ cord-022526-j9kg00qf 4077 24 diarrhea diarrhea NN cord-022526-j9kg00qf 4077 25 . . . cord-022526-j9kg00qf 4078 1 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 4078 2 is be VBZ cord-022526-j9kg00qf 4078 3 the the DT cord-022526-j9kg00qf 4078 4 toxic toxic JJ cord-022526-j9kg00qf 4078 5 principle principle NN cord-022526-j9kg00qf 4078 6 found find VBN cord-022526-j9kg00qf 4078 7 in in IN cord-022526-j9kg00qf 4078 8 beetles beetle NNS cord-022526-j9kg00qf 4078 9 of of IN cord-022526-j9kg00qf 4078 10 the the DT cord-022526-j9kg00qf 4078 11 genus genus NN cord-022526-j9kg00qf 4078 12 Epicauta Epicauta NNP cord-022526-j9kg00qf 4078 13 , , , cord-022526-j9kg00qf 4078 14 commonly commonly RB cord-022526-j9kg00qf 4078 15 known know VBN cord-022526-j9kg00qf 4078 16 as as IN cord-022526-j9kg00qf 4078 17 blister blister NN cord-022526-j9kg00qf 4078 18 beetles beetle NNS cord-022526-j9kg00qf 4078 19 . . . cord-022526-j9kg00qf 4079 1 [ [ -LRB- cord-022526-j9kg00qf 4079 2 183 183 CD cord-022526-j9kg00qf 4079 3 ] ] -RRB- cord-022526-j9kg00qf 4079 4 [ [ -LRB- cord-022526-j9kg00qf 4079 5 184 184 CD cord-022526-j9kg00qf 4079 6 ] ] -RRB- cord-022526-j9kg00qf 4079 7 [ [ -LRB- cord-022526-j9kg00qf 4079 8 185 185 CD cord-022526-j9kg00qf 4079 9 ] ] -RRB- cord-022526-j9kg00qf 4080 1 Ingestion ingestion NN cord-022526-j9kg00qf 4080 2 of of IN cord-022526-j9kg00qf 4080 3 the the DT cord-022526-j9kg00qf 4080 4 beetles beetle NNS cord-022526-j9kg00qf 4080 5 in in IN cord-022526-j9kg00qf 4080 6 contaminated contaminate VBN cord-022526-j9kg00qf 4080 7 alfalfa alfalfa NN cord-022526-j9kg00qf 4080 8 hay hay NN cord-022526-j9kg00qf 4080 9 causes cause VBZ cord-022526-j9kg00qf 4080 10 release release NN cord-022526-j9kg00qf 4080 11 of of IN cord-022526-j9kg00qf 4080 12 the the DT cord-022526-j9kg00qf 4080 13 toxin toxin NN cord-022526-j9kg00qf 4080 14 from from IN cord-022526-j9kg00qf 4080 15 the the DT cord-022526-j9kg00qf 4080 16 tissues tissue NNS cord-022526-j9kg00qf 4080 17 of of IN cord-022526-j9kg00qf 4080 18 the the DT cord-022526-j9kg00qf 4080 19 beetle beetle NN cord-022526-j9kg00qf 4080 20 and and CC cord-022526-j9kg00qf 4080 21 absorption absorption NN cord-022526-j9kg00qf 4080 22 through through IN cord-022526-j9kg00qf 4080 23 the the DT cord-022526-j9kg00qf 4080 24 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4080 25 tract tract NN cord-022526-j9kg00qf 4080 26 . . . cord-022526-j9kg00qf 4081 1 Transcutaneous transcutaneous JJ cord-022526-j9kg00qf 4081 2 absorption absorption NN cord-022526-j9kg00qf 4081 3 may may MD cord-022526-j9kg00qf 4081 4 occur occur VB cord-022526-j9kg00qf 4081 5 but but CC cord-022526-j9kg00qf 4081 6 appears appear VBZ cord-022526-j9kg00qf 4081 7 to to TO cord-022526-j9kg00qf 4081 8 be be VB cord-022526-j9kg00qf 4081 9 rare rare JJ cord-022526-j9kg00qf 4081 10 in in IN cord-022526-j9kg00qf 4081 11 horses horse NNS cord-022526-j9kg00qf 4081 12 . . . cord-022526-j9kg00qf 4082 1 184 184 CD cord-022526-j9kg00qf 4082 2 Blister Blister NNP cord-022526-j9kg00qf 4082 3 beetles beetle NNS cord-022526-j9kg00qf 4082 4 feed feed VBP cord-022526-j9kg00qf 4082 5 on on IN cord-022526-j9kg00qf 4082 6 the the DT cord-022526-j9kg00qf 4082 7 flowers flower NNS cord-022526-j9kg00qf 4082 8 of of IN cord-022526-j9kg00qf 4082 9 alfalfa alfalfa NN cord-022526-j9kg00qf 4082 10 and and CC cord-022526-j9kg00qf 4082 11 may may MD cord-022526-j9kg00qf 4082 12 be be VB cord-022526-j9kg00qf 4082 13 incorporated incorporate VBN cord-022526-j9kg00qf 4082 14 into into IN cord-022526-j9kg00qf 4082 15 processed process VBN cord-022526-j9kg00qf 4082 16 alfalfa alfalfa NN cord-022526-j9kg00qf 4082 17 hay hay NN cord-022526-j9kg00qf 4082 18 if if IN cord-022526-j9kg00qf 4082 19 the the DT cord-022526-j9kg00qf 4082 20 hay hay NN cord-022526-j9kg00qf 4082 21 is be VBZ cord-022526-j9kg00qf 4082 22 cut cut VBN cord-022526-j9kg00qf 4082 23 and and CC cord-022526-j9kg00qf 4082 24 processed process VBN cord-022526-j9kg00qf 4082 25 simultaneously simultaneously RB cord-022526-j9kg00qf 4082 26 , , , cord-022526-j9kg00qf 4082 27 as as IN cord-022526-j9kg00qf 4082 28 by by IN cord-022526-j9kg00qf 4082 29 crimping crimping NN cord-022526-j9kg00qf 4082 30 . . . cord-022526-j9kg00qf 4083 1 [ [ -LRB- cord-022526-j9kg00qf 4083 2 183 183 CD cord-022526-j9kg00qf 4083 3 ] ] -RRB- cord-022526-j9kg00qf 4083 4 [ [ -LRB- cord-022526-j9kg00qf 4083 5 184 184 CD cord-022526-j9kg00qf 4083 6 ] ] -RRB- cord-022526-j9kg00qf 4084 1 [ [ -LRB- cord-022526-j9kg00qf 4084 2 185 185 CD cord-022526-j9kg00qf 4084 3 ] ] -RRB- cord-022526-j9kg00qf 4085 1 The the DT cord-022526-j9kg00qf 4085 2 beetles beetle NNS cord-022526-j9kg00qf 4085 3 often often RB cord-022526-j9kg00qf 4085 4 swarm swarm VBP cord-022526-j9kg00qf 4085 5 , , , cord-022526-j9kg00qf 4085 6 and and CC cord-022526-j9kg00qf 4085 7 one one PRP cord-022526-j9kg00qf 4085 8 may may MD cord-022526-j9kg00qf 4085 9 find find VB cord-022526-j9kg00qf 4085 10 large large JJ cord-022526-j9kg00qf 4085 11 numbers number NNS cord-022526-j9kg00qf 4085 12 of of IN cord-022526-j9kg00qf 4085 13 beetles beetle NNS cord-022526-j9kg00qf 4085 14 in in IN cord-022526-j9kg00qf 4085 15 small small JJ cord-022526-j9kg00qf 4085 16 portions portion NNS cord-022526-j9kg00qf 4085 17 of of IN cord-022526-j9kg00qf 4085 18 hay hay NN cord-022526-j9kg00qf 4085 19 . . . cord-022526-j9kg00qf 4086 1 The the DT cord-022526-j9kg00qf 4086 2 lethal lethal JJ cord-022526-j9kg00qf 4086 3 dose dose NN cord-022526-j9kg00qf 4086 4 of of IN cord-022526-j9kg00qf 4086 5 cantharidin cantharidin NNP cord-022526-j9kg00qf 4086 6 is be VBZ cord-022526-j9kg00qf 4086 7 less less JJR cord-022526-j9kg00qf 4086 8 than than IN cord-022526-j9kg00qf 4086 9 1 1 CD cord-022526-j9kg00qf 4086 10 mg mg NNP cord-022526-j9kg00qf 4086 11 / / SYM cord-022526-j9kg00qf 4086 12 kg kg NNP cord-022526-j9kg00qf 4086 13 , , , cord-022526-j9kg00qf 4086 14 but but CC cord-022526-j9kg00qf 4086 15 the the DT cord-022526-j9kg00qf 4086 16 concentration concentration NN cord-022526-j9kg00qf 4086 17 of of IN cord-022526-j9kg00qf 4086 18 cantharidin cantharidin NNP cord-022526-j9kg00qf 4086 19 varies vary VBZ cord-022526-j9kg00qf 4086 20 from from IN cord-022526-j9kg00qf 4086 21 species specie NNS cord-022526-j9kg00qf 4086 22 to to IN cord-022526-j9kg00qf 4086 23 species specie NNS cord-022526-j9kg00qf 4086 24 of of IN cord-022526-j9kg00qf 4086 25 blister blister NN cord-022526-j9kg00qf 4086 26 beetles beetle NNS cord-022526-j9kg00qf 4086 27 and and CC cord-022526-j9kg00qf 4086 28 between between IN cord-022526-j9kg00qf 4086 29 sexes sex NNS cord-022526-j9kg00qf 4086 30 . . . cord-022526-j9kg00qf 4087 1 183 183 CD cord-022526-j9kg00qf 4087 2 , , , cord-022526-j9kg00qf 4087 3 184 184 CD cord-022526-j9kg00qf 4087 4 As as RB cord-022526-j9kg00qf 4087 5 many many JJ cord-022526-j9kg00qf 4087 6 as as IN cord-022526-j9kg00qf 4087 7 100 100 CD cord-022526-j9kg00qf 4087 8 to to IN cord-022526-j9kg00qf 4087 9 as as RB cord-022526-j9kg00qf 4087 10 few few JJ cord-022526-j9kg00qf 4087 11 as as IN cord-022526-j9kg00qf 4087 12 6 6 CD cord-022526-j9kg00qf 4087 13 to to TO cord-022526-j9kg00qf 4087 14 8 8 CD cord-022526-j9kg00qf 4087 15 beetles beetle NNS cord-022526-j9kg00qf 4087 16 may may MD cord-022526-j9kg00qf 4087 17 be be VB cord-022526-j9kg00qf 4087 18 lethal lethal JJ cord-022526-j9kg00qf 4087 19 . . . cord-022526-j9kg00qf 4088 1 Usually usually RB cord-022526-j9kg00qf 4088 2 , , , cord-022526-j9kg00qf 4088 3 only only RB cord-022526-j9kg00qf 4088 4 one one CD cord-022526-j9kg00qf 4088 5 or or CC cord-022526-j9kg00qf 4088 6 a a DT cord-022526-j9kg00qf 4088 7 few few JJ cord-022526-j9kg00qf 4088 8 horses horse NNS cord-022526-j9kg00qf 4088 9 fed feed VBD cord-022526-j9kg00qf 4088 10 contaminated contaminate VBD cord-022526-j9kg00qf 4088 11 hay hay NN cord-022526-j9kg00qf 4088 12 ingest ingest VBP cord-022526-j9kg00qf 4088 13 beetles beetle NNS cord-022526-j9kg00qf 4088 14 because because IN cord-022526-j9kg00qf 4088 15 the the DT cord-022526-j9kg00qf 4088 16 beetles beetle NNS cord-022526-j9kg00qf 4088 17 are be VBP cord-022526-j9kg00qf 4088 18 concentrated concentrate VBN cord-022526-j9kg00qf 4088 19 in in IN cord-022526-j9kg00qf 4088 20 a a DT cord-022526-j9kg00qf 4088 21 small small JJ cord-022526-j9kg00qf 4088 22 portion portion NN cord-022526-j9kg00qf 4088 23 of of IN cord-022526-j9kg00qf 4088 24 the the DT cord-022526-j9kg00qf 4088 25 hay hay NN cord-022526-j9kg00qf 4088 26 . . . cord-022526-j9kg00qf 4089 1 However however RB cord-022526-j9kg00qf 4089 2 , , , cord-022526-j9kg00qf 4089 3 outbreaks outbreak NNS cord-022526-j9kg00qf 4089 4 involving involve VBG cord-022526-j9kg00qf 4089 5 many many JJ cord-022526-j9kg00qf 4089 6 horses horse NNS cord-022526-j9kg00qf 4089 7 on on IN cord-022526-j9kg00qf 4089 8 a a DT cord-022526-j9kg00qf 4089 9 farm farm NN cord-022526-j9kg00qf 4089 10 have have VBP cord-022526-j9kg00qf 4089 11 occurred occur VBN cord-022526-j9kg00qf 4089 12 . . . cord-022526-j9kg00qf 4090 1 Most Most JJS cord-022526-j9kg00qf 4090 2 cases case NNS cord-022526-j9kg00qf 4090 3 occur occur VBP cord-022526-j9kg00qf 4090 4 in in IN cord-022526-j9kg00qf 4090 5 Texas Texas NNP cord-022526-j9kg00qf 4090 6 and and CC cord-022526-j9kg00qf 4090 7 Oklahoma Oklahoma NNP cord-022526-j9kg00qf 4090 8 , , , cord-022526-j9kg00qf 4090 9 but but CC cord-022526-j9kg00qf 4090 10 horses horse NNS cord-022526-j9kg00qf 4090 11 in in IN cord-022526-j9kg00qf 4090 12 other other JJ cord-022526-j9kg00qf 4090 13 states state NNS cord-022526-j9kg00qf 4090 14 may may MD cord-022526-j9kg00qf 4090 15 be be VB cord-022526-j9kg00qf 4090 16 affected affect VBN cord-022526-j9kg00qf 4090 17 as as RB cord-022526-j9kg00qf 4090 18 well well RB cord-022526-j9kg00qf 4090 19 , , , cord-022526-j9kg00qf 4090 20 especially especially RB cord-022526-j9kg00qf 4090 21 if if IN cord-022526-j9kg00qf 4090 22 hay hay NN cord-022526-j9kg00qf 4090 23 is be VBZ cord-022526-j9kg00qf 4090 24 imported import VBN cord-022526-j9kg00qf 4090 25 from from IN cord-022526-j9kg00qf 4090 26 states state NNS cord-022526-j9kg00qf 4090 27 where where WRB cord-022526-j9kg00qf 4090 28 blister blister NN cord-022526-j9kg00qf 4090 29 beetles beetle NNS cord-022526-j9kg00qf 4090 30 are be VBP cord-022526-j9kg00qf 4090 31 common common JJ cord-022526-j9kg00qf 4090 32 . . . cord-022526-j9kg00qf 4091 1 Peak peak NN cord-022526-j9kg00qf 4091 2 incidence incidence NN cord-022526-j9kg00qf 4091 3 is be VBZ cord-022526-j9kg00qf 4091 4 in in IN cord-022526-j9kg00qf 4091 5 late late JJ cord-022526-j9kg00qf 4091 6 summer summer NN cord-022526-j9kg00qf 4091 7 and and CC cord-022526-j9kg00qf 4091 8 fall fall NN cord-022526-j9kg00qf 4091 9 . . . cord-022526-j9kg00qf 4092 1 186 186 CD cord-022526-j9kg00qf 4093 1 The the DT cord-022526-j9kg00qf 4093 2 fatality fatality NN cord-022526-j9kg00qf 4093 3 rate rate NN cord-022526-j9kg00qf 4093 4 may may MD cord-022526-j9kg00qf 4093 5 be be VB cord-022526-j9kg00qf 4093 6 50 50 CD cord-022526-j9kg00qf 4093 7 % % NN cord-022526-j9kg00qf 4093 8 or or CC cord-022526-j9kg00qf 4093 9 greater great JJR cord-022526-j9kg00qf 4093 10 , , , cord-022526-j9kg00qf 4093 11 183 183 CD cord-022526-j9kg00qf 4093 12 , , , cord-022526-j9kg00qf 4093 13 187 187 CD cord-022526-j9kg00qf 4093 14 but but CC cord-022526-j9kg00qf 4093 15 if if IN cord-022526-j9kg00qf 4093 16 the the DT cord-022526-j9kg00qf 4093 17 patient patient NN cord-022526-j9kg00qf 4093 18 survives survive VBZ cord-022526-j9kg00qf 4093 19 several several JJ cord-022526-j9kg00qf 4093 20 days day NNS cord-022526-j9kg00qf 4093 21 , , , cord-022526-j9kg00qf 4093 22 recovery recovery NN cord-022526-j9kg00qf 4093 23 is be VBZ cord-022526-j9kg00qf 4093 24 probable probable JJ cord-022526-j9kg00qf 4093 25 . . . cord-022526-j9kg00qf 4094 1 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 4094 2 is be VBZ cord-022526-j9kg00qf 4094 3 absorbed absorb VBN cord-022526-j9kg00qf 4094 4 from from IN cord-022526-j9kg00qf 4094 5 the the DT cord-022526-j9kg00qf 4094 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4094 7 tract tract NN cord-022526-j9kg00qf 4094 8 and and CC cord-022526-j9kg00qf 4094 9 excreted excrete VBN cord-022526-j9kg00qf 4094 10 via via IN cord-022526-j9kg00qf 4094 11 the the DT cord-022526-j9kg00qf 4094 12 kidney kidney NN cord-022526-j9kg00qf 4094 13 . . . cord-022526-j9kg00qf 4095 1 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 4095 2 is be VBZ cord-022526-j9kg00qf 4095 3 a a DT cord-022526-j9kg00qf 4095 4 potent potent JJ cord-022526-j9kg00qf 4095 5 irritant irritant NN cord-022526-j9kg00qf 4095 6 , , , cord-022526-j9kg00qf 4095 7 causing cause VBG cord-022526-j9kg00qf 4095 8 acantholysis acantholysis NN cord-022526-j9kg00qf 4095 9 and and CC cord-022526-j9kg00qf 4095 10 vesicle vesicle NN cord-022526-j9kg00qf 4095 11 formation formation NN cord-022526-j9kg00qf 4095 12 when when WRB cord-022526-j9kg00qf 4095 13 applied apply VBD cord-022526-j9kg00qf 4095 14 topically topically RB cord-022526-j9kg00qf 4095 15 . . . cord-022526-j9kg00qf 4096 1 183 183 CD cord-022526-j9kg00qf 4096 2 , , , cord-022526-j9kg00qf 4096 3 185 185 CD cord-022526-j9kg00qf 4096 4 , , , cord-022526-j9kg00qf 4096 5 187 187 CD cord-022526-j9kg00qf 4097 1 The the DT cord-022526-j9kg00qf 4097 2 chemical chemical NN cord-022526-j9kg00qf 4097 3 is be VBZ cord-022526-j9kg00qf 4097 4 thought think VBN cord-022526-j9kg00qf 4097 5 to to TO cord-022526-j9kg00qf 4097 6 disrupt disrupt VB cord-022526-j9kg00qf 4097 7 oxidative oxidative JJ cord-022526-j9kg00qf 4097 8 metabolism metabolism NN cord-022526-j9kg00qf 4097 9 in in IN cord-022526-j9kg00qf 4097 10 the the DT cord-022526-j9kg00qf 4097 11 mitochondria mitochondrion NNS cord-022526-j9kg00qf 4097 12 , , , cord-022526-j9kg00qf 4097 13 causing cause VBG cord-022526-j9kg00qf 4097 14 mitochondrial mitochondrial JJ cord-022526-j9kg00qf 4097 15 swelling swelling NN cord-022526-j9kg00qf 4097 16 , , , cord-022526-j9kg00qf 4097 17 plasma plasma NN cord-022526-j9kg00qf 4097 18 membrane membrane NN cord-022526-j9kg00qf 4097 19 damage damage NN cord-022526-j9kg00qf 4097 20 , , , cord-022526-j9kg00qf 4097 21 and and CC cord-022526-j9kg00qf 4097 22 changes change NNS cord-022526-j9kg00qf 4097 23 in in IN cord-022526-j9kg00qf 4097 24 membrane membrane NN cord-022526-j9kg00qf 4097 25 permeability permeability NN cord-022526-j9kg00qf 4097 26 . . . cord-022526-j9kg00qf 4098 1 183 183 CD cord-022526-j9kg00qf 4099 1 The the DT cord-022526-j9kg00qf 4099 2 mucosa mucosa NN cord-022526-j9kg00qf 4099 3 of of IN cord-022526-j9kg00qf 4099 4 the the DT cord-022526-j9kg00qf 4099 5 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4099 6 tract tract NN cord-022526-j9kg00qf 4099 7 is be VBZ cord-022526-j9kg00qf 4099 8 affected affect VBN cord-022526-j9kg00qf 4099 9 most most RBS cord-022526-j9kg00qf 4099 10 commonly commonly RB cord-022526-j9kg00qf 4099 11 in in IN cord-022526-j9kg00qf 4099 12 horses horse NNS cord-022526-j9kg00qf 4099 13 because because IN cord-022526-j9kg00qf 4099 14 they -PRON- PRP cord-022526-j9kg00qf 4099 15 ingest ingest VBP cord-022526-j9kg00qf 4099 16 the the DT cord-022526-j9kg00qf 4099 17 toxin toxin NN cord-022526-j9kg00qf 4099 18 . . . cord-022526-j9kg00qf 4100 1 Cell cell NN cord-022526-j9kg00qf 4100 2 swelling swelling NN cord-022526-j9kg00qf 4100 3 and and CC cord-022526-j9kg00qf 4100 4 necrosis necrosis NN cord-022526-j9kg00qf 4100 5 occur occur VBP cord-022526-j9kg00qf 4100 6 , , , cord-022526-j9kg00qf 4100 7 resulting result VBG cord-022526-j9kg00qf 4100 8 in in IN cord-022526-j9kg00qf 4100 9 mucosal mucosal JJ cord-022526-j9kg00qf 4100 10 ulceration ulceration NN cord-022526-j9kg00qf 4100 11 . . . cord-022526-j9kg00qf 4101 1 Oral oral JJ cord-022526-j9kg00qf 4101 2 , , , cord-022526-j9kg00qf 4101 3 esophageal esophageal JJ cord-022526-j9kg00qf 4101 4 , , , cord-022526-j9kg00qf 4101 5 gastric gastric JJ cord-022526-j9kg00qf 4101 6 , , , cord-022526-j9kg00qf 4101 7 and and CC cord-022526-j9kg00qf 4101 8 small small JJ cord-022526-j9kg00qf 4101 9 and and CC cord-022526-j9kg00qf 4101 10 large large JJ cord-022526-j9kg00qf 4101 11 intestinal intestinal JJ cord-022526-j9kg00qf 4101 12 ulceration ulceration NN cord-022526-j9kg00qf 4101 13 have have VBP cord-022526-j9kg00qf 4101 14 been be VBN cord-022526-j9kg00qf 4101 15 observed observe VBN cord-022526-j9kg00qf 4101 16 in in IN cord-022526-j9kg00qf 4101 17 natural natural JJ cord-022526-j9kg00qf 4101 18 and and CC cord-022526-j9kg00qf 4101 19 experimental experimental JJ cord-022526-j9kg00qf 4101 20 canthariasis canthariasis NN cord-022526-j9kg00qf 4101 21 . . . cord-022526-j9kg00qf 4102 1 183 183 CD cord-022526-j9kg00qf 4102 2 , , , cord-022526-j9kg00qf 4102 3 185 185 CD cord-022526-j9kg00qf 4102 4 , , , cord-022526-j9kg00qf 4102 5 187 187 CD cord-022526-j9kg00qf 4102 6 Severe severe JJ cord-022526-j9kg00qf 4102 7 fibrinous fibrinous JJ cord-022526-j9kg00qf 4102 8 to to IN cord-022526-j9kg00qf 4102 9 pseudomembranous pseudomembranous JJ cord-022526-j9kg00qf 4102 10 inflammation inflammation NN cord-022526-j9kg00qf 4102 11 and and CC cord-022526-j9kg00qf 4102 12 submucosal submucosal NNP cord-022526-j9kg00qf 4102 13 edema edema NN cord-022526-j9kg00qf 4102 14 of of IN cord-022526-j9kg00qf 4102 15 the the DT cord-022526-j9kg00qf 4102 16 intestine intestine NN cord-022526-j9kg00qf 4102 17 also also RB cord-022526-j9kg00qf 4102 18 have have VBP cord-022526-j9kg00qf 4102 19 been be VBN cord-022526-j9kg00qf 4102 20 reported report VBN cord-022526-j9kg00qf 4102 21 . . . cord-022526-j9kg00qf 4103 1 Diarrhea diarrhea NN cord-022526-j9kg00qf 4103 2 probably probably RB cord-022526-j9kg00qf 4103 3 results result VBZ cord-022526-j9kg00qf 4103 4 from from IN cord-022526-j9kg00qf 4103 5 the the DT cord-022526-j9kg00qf 4103 6 severe severe JJ cord-022526-j9kg00qf 4103 7 ulceration ulceration NN cord-022526-j9kg00qf 4103 8 and and CC cord-022526-j9kg00qf 4103 9 inflammation inflammation NN cord-022526-j9kg00qf 4103 10 of of IN cord-022526-j9kg00qf 4103 11 the the DT cord-022526-j9kg00qf 4103 12 large large JJ cord-022526-j9kg00qf 4103 13 intestine intestine NN cord-022526-j9kg00qf 4103 14 , , , cord-022526-j9kg00qf 4103 15 causing cause VBG cord-022526-j9kg00qf 4103 16 increased increase VBN cord-022526-j9kg00qf 4103 17 secretion secretion NN cord-022526-j9kg00qf 4103 18 of of IN cord-022526-j9kg00qf 4103 19 water water NN cord-022526-j9kg00qf 4103 20 , , , cord-022526-j9kg00qf 4103 21 electrolytes electrolyte NNS cord-022526-j9kg00qf 4103 22 , , , cord-022526-j9kg00qf 4103 23 and and CC cord-022526-j9kg00qf 4103 24 protein protein NN cord-022526-j9kg00qf 4103 25 and and CC cord-022526-j9kg00qf 4103 26 decreased decrease VBD cord-022526-j9kg00qf 4103 27 absorption absorption NN cord-022526-j9kg00qf 4103 28 of of IN cord-022526-j9kg00qf 4103 29 fluid fluid NN cord-022526-j9kg00qf 4103 30 . . . cord-022526-j9kg00qf 4104 1 Large large JJ cord-022526-j9kg00qf 4104 2 volumes volume NNS cord-022526-j9kg00qf 4104 3 of of IN cord-022526-j9kg00qf 4104 4 fluid fluid NN cord-022526-j9kg00qf 4104 5 and and CC cord-022526-j9kg00qf 4104 6 protein protein NN cord-022526-j9kg00qf 4104 7 are be VBP cord-022526-j9kg00qf 4104 8 lost lose VBN cord-022526-j9kg00qf 4104 9 in in IN cord-022526-j9kg00qf 4104 10 the the DT cord-022526-j9kg00qf 4104 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4104 12 tract tract NN cord-022526-j9kg00qf 4104 13 , , , cord-022526-j9kg00qf 4104 14 causing cause VBG cord-022526-j9kg00qf 4104 15 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 4104 16 and and CC cord-022526-j9kg00qf 4104 17 profound profound JJ cord-022526-j9kg00qf 4104 18 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4104 19 in in IN cord-022526-j9kg00qf 4104 20 some some DT cord-022526-j9kg00qf 4104 21 cases case NNS cord-022526-j9kg00qf 4104 22 . . . cord-022526-j9kg00qf 4105 1 183 183 CD cord-022526-j9kg00qf 4105 2 , , , cord-022526-j9kg00qf 4105 3 184 184 CD cord-022526-j9kg00qf 4105 4 , , , cord-022526-j9kg00qf 4105 5 187 187 CD cord-022526-j9kg00qf 4105 6 Cystitis cystiti NNS cord-022526-j9kg00qf 4105 7 and and CC cord-022526-j9kg00qf 4105 8 myocarditis myocarditis NN cord-022526-j9kg00qf 4105 9 occur occur VBP cord-022526-j9kg00qf 4105 10 in in IN cord-022526-j9kg00qf 4105 11 natural natural JJ cord-022526-j9kg00qf 4105 12 and and CC cord-022526-j9kg00qf 4105 13 experimentally experimentally RB cord-022526-j9kg00qf 4105 14 produced produce VBN cord-022526-j9kg00qf 4105 15 cases case NNS cord-022526-j9kg00qf 4105 16 of of IN cord-022526-j9kg00qf 4105 17 cantharidin cantharidin JJ cord-022526-j9kg00qf 4105 18 toxicity toxicity NN cord-022526-j9kg00qf 4105 19 . . . cord-022526-j9kg00qf 4106 1 183 183 CD cord-022526-j9kg00qf 4106 2 , , , cord-022526-j9kg00qf 4106 3 185 185 CD cord-022526-j9kg00qf 4106 4 , , , cord-022526-j9kg00qf 4106 5 187 187 CD cord-022526-j9kg00qf 4106 6 Cystitis Cystitis NNP cord-022526-j9kg00qf 4106 7 occurs occur VBZ cord-022526-j9kg00qf 4106 8 because because IN cord-022526-j9kg00qf 4106 9 renal renal JJ cord-022526-j9kg00qf 4106 10 excretion excretion NN cord-022526-j9kg00qf 4106 11 of of IN cord-022526-j9kg00qf 4106 12 cantharidin cantharidin JJ cord-022526-j9kg00qf 4106 13 results result NNS cord-022526-j9kg00qf 4106 14 in in IN cord-022526-j9kg00qf 4106 15 high high JJ cord-022526-j9kg00qf 4106 16 concentrations concentration NNS cord-022526-j9kg00qf 4106 17 in in IN cord-022526-j9kg00qf 4106 18 urine urine NN cord-022526-j9kg00qf 4106 19 . . . cord-022526-j9kg00qf 4107 1 Occasionally occasionally RB cord-022526-j9kg00qf 4107 2 , , , cord-022526-j9kg00qf 4107 3 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4107 4 cystitis cystitis NN cord-022526-j9kg00qf 4107 5 may may MD cord-022526-j9kg00qf 4107 6 occur occur VB cord-022526-j9kg00qf 4107 7 , , , cord-022526-j9kg00qf 4107 8 with with IN cord-022526-j9kg00qf 4107 9 hematuria hematuria NN cord-022526-j9kg00qf 4107 10 or or CC cord-022526-j9kg00qf 4107 11 frank frank JJ cord-022526-j9kg00qf 4107 12 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4107 13 into into IN cord-022526-j9kg00qf 4107 14 the the DT cord-022526-j9kg00qf 4107 15 bladder bladder NN cord-022526-j9kg00qf 4107 16 . . . cord-022526-j9kg00qf 4108 1 183 183 CD cord-022526-j9kg00qf 4109 1 The the DT cord-022526-j9kg00qf 4109 2 cause cause NN cord-022526-j9kg00qf 4109 3 of of IN cord-022526-j9kg00qf 4109 4 the the DT cord-022526-j9kg00qf 4109 5 myocarditis myocarditis NN cord-022526-j9kg00qf 4109 6 and and CC cord-022526-j9kg00qf 4109 7 myocardial myocardial JJ cord-022526-j9kg00qf 4109 8 necrosis necrosis NN cord-022526-j9kg00qf 4109 9 is be VBZ cord-022526-j9kg00qf 4109 10 unknown unknown JJ cord-022526-j9kg00qf 4109 11 but but CC cord-022526-j9kg00qf 4109 12 also also RB cord-022526-j9kg00qf 4109 13 may may MD cord-022526-j9kg00qf 4109 14 be be VB cord-022526-j9kg00qf 4109 15 a a DT cord-022526-j9kg00qf 4109 16 direct direct JJ cord-022526-j9kg00qf 4109 17 effect effect NN cord-022526-j9kg00qf 4109 18 of of IN cord-022526-j9kg00qf 4109 19 the the DT cord-022526-j9kg00qf 4109 20 toxin toxin NN cord-022526-j9kg00qf 4109 21 on on IN cord-022526-j9kg00qf 4109 22 the the DT cord-022526-j9kg00qf 4109 23 myocardium myocardium NN cord-022526-j9kg00qf 4109 24 . . . cord-022526-j9kg00qf 4110 1 Elevated elevated JJ cord-022526-j9kg00qf 4110 2 plasma plasma NN cord-022526-j9kg00qf 4110 3 creatine creatine NN cord-022526-j9kg00qf 4110 4 kinase kinase NN cord-022526-j9kg00qf 4110 5 activity activity NN cord-022526-j9kg00qf 4110 6 often often RB cord-022526-j9kg00qf 4110 7 occurs occur VBZ cord-022526-j9kg00qf 4110 8 and and CC cord-022526-j9kg00qf 4110 9 has have VBZ cord-022526-j9kg00qf 4110 10 been be VBN cord-022526-j9kg00qf 4110 11 postulated postulate VBN cord-022526-j9kg00qf 4110 12 to to TO cord-022526-j9kg00qf 4110 13 arise arise VB cord-022526-j9kg00qf 4110 14 from from IN cord-022526-j9kg00qf 4110 15 the the DT cord-022526-j9kg00qf 4110 16 damaged damage VBN cord-022526-j9kg00qf 4110 17 myocardium myocardium NN cord-022526-j9kg00qf 4110 18 . . . cord-022526-j9kg00qf 4111 1 183 183 CD cord-022526-j9kg00qf 4111 2 , , , cord-022526-j9kg00qf 4111 3 184 184 CD cord-022526-j9kg00qf 4111 4 Horses horse NNS cord-022526-j9kg00qf 4111 5 have have VBP cord-022526-j9kg00qf 4111 6 a a DT cord-022526-j9kg00qf 4111 7 characteristically characteristically RB cord-022526-j9kg00qf 4111 8 stiff stiff JJ cord-022526-j9kg00qf 4111 9 gait gait NN cord-022526-j9kg00qf 4111 10 , , , cord-022526-j9kg00qf 4111 11 but but CC cord-022526-j9kg00qf 4111 12 histopathologic histopathologic JJ cord-022526-j9kg00qf 4111 13 evidence evidence NN cord-022526-j9kg00qf 4111 14 of of IN cord-022526-j9kg00qf 4111 15 skeletal skeletal JJ cord-022526-j9kg00qf 4111 16 muscle muscle NN cord-022526-j9kg00qf 4111 17 injury injury NN cord-022526-j9kg00qf 4111 18 that that WDT cord-022526-j9kg00qf 4111 19 explains explain VBZ cord-022526-j9kg00qf 4111 20 the the DT cord-022526-j9kg00qf 4111 21 elevated elevated JJ cord-022526-j9kg00qf 4111 22 plasma plasma NN cord-022526-j9kg00qf 4111 23 creatine creatine NN cord-022526-j9kg00qf 4111 24 kinase kinase NN cord-022526-j9kg00qf 4111 25 activity activity NN cord-022526-j9kg00qf 4111 26 has have VBZ cord-022526-j9kg00qf 4111 27 not not RB cord-022526-j9kg00qf 4111 28 been be VBN cord-022526-j9kg00qf 4111 29 observed observe VBN cord-022526-j9kg00qf 4111 30 . . . cord-022526-j9kg00qf 4112 1 184 184 CD cord-022526-j9kg00qf 4113 1 The the DT cord-022526-j9kg00qf 4113 2 kidneys kidney NNS cord-022526-j9kg00qf 4113 3 are be VBP cord-022526-j9kg00qf 4113 4 often often RB cord-022526-j9kg00qf 4113 5 pale pale JJ cord-022526-j9kg00qf 4113 6 , , , cord-022526-j9kg00qf 4113 7 swollen swollen JJ cord-022526-j9kg00qf 4113 8 , , , cord-022526-j9kg00qf 4113 9 and and CC cord-022526-j9kg00qf 4113 10 moist moist JJ cord-022526-j9kg00qf 4113 11 , , , cord-022526-j9kg00qf 4113 12 with with IN cord-022526-j9kg00qf 4113 13 occasional occasional JJ cord-022526-j9kg00qf 4113 14 infarcts infarct NNS cord-022526-j9kg00qf 4113 15 . . . cord-022526-j9kg00qf 4114 1 185 185 CD cord-022526-j9kg00qf 4114 2 Hypocalcemia Hypocalcemia NNP cord-022526-j9kg00qf 4114 3 and and CC cord-022526-j9kg00qf 4114 4 hypomagnesemia hypomagnesemia NN cord-022526-j9kg00qf 4114 5 are be VBP cord-022526-j9kg00qf 4114 6 biochemical biochemical JJ cord-022526-j9kg00qf 4114 7 features feature NNS cord-022526-j9kg00qf 4114 8 of of IN cord-022526-j9kg00qf 4114 9 cantharidin cantharidin JJ cord-022526-j9kg00qf 4114 10 toxicity toxicity NN cord-022526-j9kg00qf 4114 11 in in IN cord-022526-j9kg00qf 4114 12 horses horse NNS cord-022526-j9kg00qf 4114 13 that that WDT cord-022526-j9kg00qf 4114 14 have have VBP cord-022526-j9kg00qf 4114 15 not not RB cord-022526-j9kg00qf 4114 16 been be VBN cord-022526-j9kg00qf 4114 17 explained explain VBN cord-022526-j9kg00qf 4114 18 . . . cord-022526-j9kg00qf 4115 1 183 183 CD cord-022526-j9kg00qf 4115 2 , , , cord-022526-j9kg00qf 4115 3 184 184 CD cord-022526-j9kg00qf 4115 4 , , , cord-022526-j9kg00qf 4115 5 187 187 CD cord-022526-j9kg00qf 4115 6 Hypocalcemia Hypocalcemia NNP cord-022526-j9kg00qf 4115 7 may may MD cord-022526-j9kg00qf 4115 8 occur occur VB cord-022526-j9kg00qf 4115 9 from from IN cord-022526-j9kg00qf 4115 10 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4115 11 , , , cord-022526-j9kg00qf 4115 12 but but CC cord-022526-j9kg00qf 4115 13 the the DT cord-022526-j9kg00qf 4115 14 ionized ionized JJ cord-022526-j9kg00qf 4115 15 calcium calcium NN cord-022526-j9kg00qf 4115 16 concentration concentration NN cord-022526-j9kg00qf 4115 17 often often RB cord-022526-j9kg00qf 4115 18 is be VBZ cord-022526-j9kg00qf 4115 19 decreased decrease VBN cord-022526-j9kg00qf 4115 20 along along IN cord-022526-j9kg00qf 4115 21 with with IN cord-022526-j9kg00qf 4115 22 the the DT cord-022526-j9kg00qf 4115 23 total total JJ cord-022526-j9kg00qf 4115 24 calcium calcium NN cord-022526-j9kg00qf 4115 25 concentration concentration NN cord-022526-j9kg00qf 4115 26 , , , cord-022526-j9kg00qf 4115 27 indicating indicate VBG cord-022526-j9kg00qf 4115 28 that that IN cord-022526-j9kg00qf 4115 29 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4115 30 is be VBZ cord-022526-j9kg00qf 4115 31 not not RB cord-022526-j9kg00qf 4115 32 responsible responsible JJ cord-022526-j9kg00qf 4115 33 for for IN cord-022526-j9kg00qf 4115 34 the the DT cord-022526-j9kg00qf 4115 35 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4115 36 . . . cord-022526-j9kg00qf 4116 1 184 184 CD cord-022526-j9kg00qf 4117 1 In in IN cord-022526-j9kg00qf 4117 2 addition addition NN cord-022526-j9kg00qf 4117 3 , , , cord-022526-j9kg00qf 4117 4 clinical clinical JJ cord-022526-j9kg00qf 4117 5 signs sign NNS cord-022526-j9kg00qf 4117 6 of of IN cord-022526-j9kg00qf 4117 7 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4117 8 , , , cord-022526-j9kg00qf 4117 9 such such JJ cord-022526-j9kg00qf 4117 10 as as IN cord-022526-j9kg00qf 4117 11 synchronous synchronous JJ cord-022526-j9kg00qf 4117 12 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4117 13 flutter flutter NN cord-022526-j9kg00qf 4117 14 , , , cord-022526-j9kg00qf 4117 15 are be VBP cord-022526-j9kg00qf 4117 16 often often RB cord-022526-j9kg00qf 4117 17 associated associate VBN cord-022526-j9kg00qf 4117 18 with with IN cord-022526-j9kg00qf 4117 19 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4117 20 from from IN cord-022526-j9kg00qf 4117 21 cantharidin cantharidin JJ cord-022526-j9kg00qf 4117 22 toxicity toxicity NN cord-022526-j9kg00qf 4117 23 . . . cord-022526-j9kg00qf 4118 1 Hypocalcemia Hypocalcemia NNP cord-022526-j9kg00qf 4118 2 associated associate VBN cord-022526-j9kg00qf 4118 3 with with IN cord-022526-j9kg00qf 4118 4 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4118 5 alone alone RB cord-022526-j9kg00qf 4118 6 does do VBZ cord-022526-j9kg00qf 4118 7 not not RB cord-022526-j9kg00qf 4118 8 produce produce VB cord-022526-j9kg00qf 4118 9 clinical clinical JJ cord-022526-j9kg00qf 4118 10 signs sign NNS cord-022526-j9kg00qf 4118 11 . . . cord-022526-j9kg00qf 4119 1 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 4119 2 toxicity toxicity NN cord-022526-j9kg00qf 4119 3 can can MD cord-022526-j9kg00qf 4119 4 cause cause VB cord-022526-j9kg00qf 4119 5 a a DT cord-022526-j9kg00qf 4119 6 range range NN cord-022526-j9kg00qf 4119 7 of of IN cord-022526-j9kg00qf 4119 8 clinical clinical JJ cord-022526-j9kg00qf 4119 9 signs sign NNS cord-022526-j9kg00qf 4119 10 from from IN cord-022526-j9kg00qf 4119 11 mild mild JJ cord-022526-j9kg00qf 4119 12 depression depression NN cord-022526-j9kg00qf 4119 13 and and CC cord-022526-j9kg00qf 4119 14 abdominal abdominal JJ cord-022526-j9kg00qf 4119 15 discomfort discomfort NN cord-022526-j9kg00qf 4119 16 to to IN cord-022526-j9kg00qf 4119 17 fulminant fulminant JJ cord-022526-j9kg00qf 4119 18 signs sign NNS cord-022526-j9kg00qf 4119 19 of of IN cord-022526-j9kg00qf 4119 20 toxemia toxemia NN cord-022526-j9kg00qf 4119 21 and and CC cord-022526-j9kg00qf 4119 22 rapid rapid JJ cord-022526-j9kg00qf 4119 23 death death NN cord-022526-j9kg00qf 4119 24 , , , cord-022526-j9kg00qf 4119 25 depending depend VBG cord-022526-j9kg00qf 4119 26 on on IN cord-022526-j9kg00qf 4119 27 the the DT cord-022526-j9kg00qf 4119 28 ingested ingested JJ cord-022526-j9kg00qf 4119 29 dose dose NN cord-022526-j9kg00qf 4119 30 of of IN cord-022526-j9kg00qf 4119 31 toxin toxin NN cord-022526-j9kg00qf 4119 32 . . . cord-022526-j9kg00qf 4120 1 Most most RBS cord-022526-j9kg00qf 4120 2 commonly commonly RB cord-022526-j9kg00qf 4120 3 , , , cord-022526-j9kg00qf 4120 4 clinical clinical JJ cord-022526-j9kg00qf 4120 5 signs sign NNS cord-022526-j9kg00qf 4120 6 include include VBP cord-022526-j9kg00qf 4120 7 depression depression NN cord-022526-j9kg00qf 4120 8 , , , cord-022526-j9kg00qf 4120 9 sweating sweating NN cord-022526-j9kg00qf 4120 10 , , , cord-022526-j9kg00qf 4120 11 irritability irritability NN cord-022526-j9kg00qf 4120 12 , , , cord-022526-j9kg00qf 4120 13 abdominal abdominal JJ cord-022526-j9kg00qf 4120 14 pain pain NN cord-022526-j9kg00qf 4120 15 , , , cord-022526-j9kg00qf 4120 16 elevated elevated JJ cord-022526-j9kg00qf 4120 17 heart heart NN cord-022526-j9kg00qf 4120 18 and and CC cord-022526-j9kg00qf 4120 19 respiratory respiratory JJ cord-022526-j9kg00qf 4120 20 rates rate NNS cord-022526-j9kg00qf 4120 21 , , , cord-022526-j9kg00qf 4120 22 fever fever NN cord-022526-j9kg00qf 4120 23 , , , cord-022526-j9kg00qf 4120 24 polyuria polyuria NN cord-022526-j9kg00qf 4120 25 , , , cord-022526-j9kg00qf 4120 26 polydypsia polydypsia NN cord-022526-j9kg00qf 4120 27 , , , cord-022526-j9kg00qf 4120 28 and and CC cord-022526-j9kg00qf 4120 29 profuse profuse JJ cord-022526-j9kg00qf 4120 30 diarrhea diarrhea NN cord-022526-j9kg00qf 4120 31 . . . cord-022526-j9kg00qf 4121 1 183 183 CD cord-022526-j9kg00qf 4121 2 , , , cord-022526-j9kg00qf 4121 3 184 184 CD cord-022526-j9kg00qf 4121 4 , , , cord-022526-j9kg00qf 4121 5 187 187 CD cord-022526-j9kg00qf 4121 6 Blood blood NN cord-022526-j9kg00qf 4121 7 is be VBZ cord-022526-j9kg00qf 4121 8 rarely rarely RB cord-022526-j9kg00qf 4121 9 visible visible JJ cord-022526-j9kg00qf 4121 10 in in IN cord-022526-j9kg00qf 4121 11 the the DT cord-022526-j9kg00qf 4121 12 feces fece NNS cord-022526-j9kg00qf 4121 13 . . . cord-022526-j9kg00qf 4122 1 Affected affected JJ cord-022526-j9kg00qf 4122 2 horses horse NNS cord-022526-j9kg00qf 4122 3 frequently frequently RB cord-022526-j9kg00qf 4122 4 posture posture VBP cord-022526-j9kg00qf 4122 5 to to TO cord-022526-j9kg00qf 4122 6 urinate urinate VB cord-022526-j9kg00qf 4122 7 ; ; : cord-022526-j9kg00qf 4122 8 indeed indeed RB cord-022526-j9kg00qf 4122 9 , , , cord-022526-j9kg00qf 4122 10 stranguria stranguria NNP cord-022526-j9kg00qf 4122 11 and and CC cord-022526-j9kg00qf 4122 12 pollakiuria pollakiuria NNP cord-022526-j9kg00qf 4122 13 are be VBP cord-022526-j9kg00qf 4122 14 characteristic characteristic JJ cord-022526-j9kg00qf 4122 15 of of IN cord-022526-j9kg00qf 4122 16 cantharidin cantharidin JJ cord-022526-j9kg00qf 4122 17 toxicity toxicity NN cord-022526-j9kg00qf 4122 18 . . . cord-022526-j9kg00qf 4123 1 183 183 CD cord-022526-j9kg00qf 4123 2 Signs sign NNS cord-022526-j9kg00qf 4123 3 of of IN cord-022526-j9kg00qf 4123 4 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4123 5 include include VBP cord-022526-j9kg00qf 4123 6 synchronous synchronous JJ cord-022526-j9kg00qf 4123 7 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4123 8 flutter flutter NN cord-022526-j9kg00qf 4123 9 and and CC cord-022526-j9kg00qf 4123 10 tremors tremor NNS cord-022526-j9kg00qf 4123 11 . . . cord-022526-j9kg00qf 4124 1 A a DT cord-022526-j9kg00qf 4124 2 stiff stiff JJ cord-022526-j9kg00qf 4124 3 and and CC cord-022526-j9kg00qf 4124 4 stilted stilted JJ cord-022526-j9kg00qf 4124 5 gait gait NN cord-022526-j9kg00qf 4124 6 may may MD cord-022526-j9kg00qf 4124 7 be be VB cord-022526-j9kg00qf 4124 8 evident evident JJ cord-022526-j9kg00qf 4124 9 . . . cord-022526-j9kg00qf 4125 1 One one CD cord-022526-j9kg00qf 4125 2 may may MD cord-022526-j9kg00qf 4125 3 note note VB cord-022526-j9kg00qf 4125 4 neurologic neurologic JJ cord-022526-j9kg00qf 4125 5 signs sign NNS cord-022526-j9kg00qf 4125 6 such such JJ cord-022526-j9kg00qf 4125 7 as as IN cord-022526-j9kg00qf 4125 8 head head NN cord-022526-j9kg00qf 4125 9 pressing press VBG cord-022526-j9kg00qf 4125 10 , , , cord-022526-j9kg00qf 4125 11 swaying sway VBG cord-022526-j9kg00qf 4125 12 , , , cord-022526-j9kg00qf 4125 13 and and CC cord-022526-j9kg00qf 4125 14 disorientation disorientation NN cord-022526-j9kg00qf 4125 15 . . . cord-022526-j9kg00qf 4126 1 187 187 CD cord-022526-j9kg00qf 4126 2 Signs sign NNS cord-022526-j9kg00qf 4126 3 of of IN cord-022526-j9kg00qf 4126 4 systemic systemic JJ cord-022526-j9kg00qf 4126 5 inflammation inflammation NN cord-022526-j9kg00qf 4126 6 from from IN cord-022526-j9kg00qf 4126 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4126 8 may may MD cord-022526-j9kg00qf 4126 9 be be VB cord-022526-j9kg00qf 4126 10 apparent apparent JJ cord-022526-j9kg00qf 4126 11 in in IN cord-022526-j9kg00qf 4126 12 severe severe JJ cord-022526-j9kg00qf 4126 13 cases case NNS cord-022526-j9kg00qf 4126 14 . . . cord-022526-j9kg00qf 4127 1 Some some DT cord-022526-j9kg00qf 4127 2 horses horse NNS cord-022526-j9kg00qf 4127 3 develop develop VBP cord-022526-j9kg00qf 4127 4 severe severe JJ cord-022526-j9kg00qf 4127 5 depression depression NN cord-022526-j9kg00qf 4127 6 and and CC cord-022526-j9kg00qf 4127 7 toxemia toxemia NN cord-022526-j9kg00qf 4127 8 and and CC cord-022526-j9kg00qf 4127 9 may may MD cord-022526-j9kg00qf 4127 10 die die VB cord-022526-j9kg00qf 4127 11 within within IN cord-022526-j9kg00qf 4127 12 hours hour NNS cord-022526-j9kg00qf 4127 13 after after IN cord-022526-j9kg00qf 4127 14 ingestion ingestion NN cord-022526-j9kg00qf 4127 15 of of IN cord-022526-j9kg00qf 4127 16 cantharidin cantharidin NNS cord-022526-j9kg00qf 4127 17 without without IN cord-022526-j9kg00qf 4127 18 developing develop VBG cord-022526-j9kg00qf 4127 19 diarrhea diarrhea NN cord-022526-j9kg00qf 4127 20 . . . cord-022526-j9kg00qf 4128 1 183 183 CD cord-022526-j9kg00qf 4128 2 , , , cord-022526-j9kg00qf 4128 3 187 187 CD cord-022526-j9kg00qf 4128 4 Hematologic Hematologic NNP cord-022526-j9kg00qf 4128 5 abnormalities abnormality NNS cord-022526-j9kg00qf 4128 6 include include VBP cord-022526-j9kg00qf 4128 7 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 4128 8 and and CC cord-022526-j9kg00qf 4128 9 neutrophilic neutrophilic NNP cord-022526-j9kg00qf 4128 10 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 4128 11 . . . cord-022526-j9kg00qf 4129 1 Occasionally occasionally RB cord-022526-j9kg00qf 4129 2 , , , cord-022526-j9kg00qf 4129 3 neutropenia neutropenia NN cord-022526-j9kg00qf 4129 4 and and CC cord-022526-j9kg00qf 4129 5 leukopenia leukopenia NN cord-022526-j9kg00qf 4129 6 may may MD cord-022526-j9kg00qf 4129 7 accompany accompany VB cord-022526-j9kg00qf 4129 8 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4129 9 . . . cord-022526-j9kg00qf 4130 1 Serum serum NN cord-022526-j9kg00qf 4130 2 biochemical biochemical JJ cord-022526-j9kg00qf 4130 3 analysis analysis NN cord-022526-j9kg00qf 4130 4 usually usually RB cord-022526-j9kg00qf 4130 5 reveals reveal VBZ cord-022526-j9kg00qf 4130 6 elevated elevate VBN cord-022526-j9kg00qf 4130 7 creatine creatine NN cord-022526-j9kg00qf 4130 8 kinase kinase NN cord-022526-j9kg00qf 4130 9 activity activity NN cord-022526-j9kg00qf 4130 10 , , , cord-022526-j9kg00qf 4130 11 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4130 12 , , , cord-022526-j9kg00qf 4130 13 and and CC cord-022526-j9kg00qf 4130 14 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 4130 15 . . . cord-022526-j9kg00qf 4131 1 183 183 CD cord-022526-j9kg00qf 4131 2 , , , cord-022526-j9kg00qf 4131 3 184 184 CD cord-022526-j9kg00qf 4131 4 Biochemical biochemical JJ cord-022526-j9kg00qf 4131 5 abnormalities abnormality NNS cord-022526-j9kg00qf 4131 6 include include VBP cord-022526-j9kg00qf 4131 7 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4131 8 ( ( -LRB- cord-022526-j9kg00qf 4131 9 ionized ionized JJ cord-022526-j9kg00qf 4131 10 and and CC cord-022526-j9kg00qf 4131 11 total total JJ cord-022526-j9kg00qf 4131 12 calcium calcium NN cord-022526-j9kg00qf 4131 13 concentrations concentration NNS cord-022526-j9kg00qf 4131 14 ) ) -RRB- cord-022526-j9kg00qf 4131 15 , , , cord-022526-j9kg00qf 4131 16 hypomagnesemia hypomagnesemia NN cord-022526-j9kg00qf 4131 17 , , , cord-022526-j9kg00qf 4131 18 and and CC cord-022526-j9kg00qf 4131 19 azotemia azotemia NN cord-022526-j9kg00qf 4131 20 . . . cord-022526-j9kg00qf 4132 1 183 183 CD cord-022526-j9kg00qf 4132 2 , , , cord-022526-j9kg00qf 4132 3 184 184 CD cord-022526-j9kg00qf 4132 4 , , , cord-022526-j9kg00qf 4132 5 187 187 CD cord-022526-j9kg00qf 4132 6 Urine urine NN cord-022526-j9kg00qf 4132 7 specific specific JJ cord-022526-j9kg00qf 4132 8 gravity gravity NN cord-022526-j9kg00qf 4132 9 is be VBZ cord-022526-j9kg00qf 4132 10 characteristically characteristically RB cord-022526-j9kg00qf 4132 11 in in IN cord-022526-j9kg00qf 4132 12 the the DT cord-022526-j9kg00qf 4132 13 hyposthenuric hyposthenuric JJ cord-022526-j9kg00qf 4132 14 range range NN cord-022526-j9kg00qf 4132 15 . . . cord-022526-j9kg00qf 4133 1 183 183 CD cord-022526-j9kg00qf 4133 2 , , , cord-022526-j9kg00qf 4133 3 184 184 CD cord-022526-j9kg00qf 4133 4 Microscopic microscopic JJ cord-022526-j9kg00qf 4133 5 hematuria hematuria NN cord-022526-j9kg00qf 4133 6 and and CC cord-022526-j9kg00qf 4133 7 mild mild JJ cord-022526-j9kg00qf 4133 8 proteinuria proteinuria NN cord-022526-j9kg00qf 4133 9 may may MD cord-022526-j9kg00qf 4133 10 be be VB cord-022526-j9kg00qf 4133 11 evident evident JJ cord-022526-j9kg00qf 4133 12 . . . cord-022526-j9kg00qf 4134 1 Fecal fecal JJ cord-022526-j9kg00qf 4134 2 occult occult JJ cord-022526-j9kg00qf 4134 3 blood blood NN cord-022526-j9kg00qf 4134 4 is be VBZ cord-022526-j9kg00qf 4134 5 often often RB cord-022526-j9kg00qf 4134 6 present present JJ cord-022526-j9kg00qf 4134 7 , , , cord-022526-j9kg00qf 4134 8 but but CC cord-022526-j9kg00qf 4134 9 hematochezia hematochezia NNP cord-022526-j9kg00qf 4134 10 is be VBZ cord-022526-j9kg00qf 4134 11 unusual unusual JJ cord-022526-j9kg00qf 4134 12 . . . cord-022526-j9kg00qf 4135 1 One one PRP cord-022526-j9kg00qf 4135 2 can can MD cord-022526-j9kg00qf 4135 3 make make VB cord-022526-j9kg00qf 4135 4 a a DT cord-022526-j9kg00qf 4135 5 tentative tentative JJ cord-022526-j9kg00qf 4135 6 diagnosis diagnosis NN cord-022526-j9kg00qf 4135 7 based base VBN cord-022526-j9kg00qf 4135 8 on on IN cord-022526-j9kg00qf 4135 9 clinical clinical JJ cord-022526-j9kg00qf 4135 10 signs sign NNS cord-022526-j9kg00qf 4135 11 and and CC cord-022526-j9kg00qf 4135 12 the the DT cord-022526-j9kg00qf 4135 13 finding finding NN cord-022526-j9kg00qf 4135 14 of of IN cord-022526-j9kg00qf 4135 15 blister blister NN cord-022526-j9kg00qf 4135 16 beetles beetle NNS cord-022526-j9kg00qf 4135 17 in in IN cord-022526-j9kg00qf 4135 18 the the DT cord-022526-j9kg00qf 4135 19 hay hay NN cord-022526-j9kg00qf 4135 20 . . . cord-022526-j9kg00qf 4136 1 Determining determine VBG cord-022526-j9kg00qf 4136 2 the the DT cord-022526-j9kg00qf 4136 3 species specie NNS cord-022526-j9kg00qf 4136 4 of of IN cord-022526-j9kg00qf 4136 5 the the DT cord-022526-j9kg00qf 4136 6 insects insect NNS cord-022526-j9kg00qf 4136 7 may may MD cord-022526-j9kg00qf 4136 8 be be VB cord-022526-j9kg00qf 4136 9 necessary necessary JJ cord-022526-j9kg00qf 4136 10 to to TO cord-022526-j9kg00qf 4136 11 estimate estimate VB cord-022526-j9kg00qf 4136 12 the the DT cord-022526-j9kg00qf 4136 13 amount amount NN cord-022526-j9kg00qf 4136 14 of of IN cord-022526-j9kg00qf 4136 15 cantharidin cantharidin NNP cord-022526-j9kg00qf 4136 16 ingested ingest VBN cord-022526-j9kg00qf 4136 17 . . . cord-022526-j9kg00qf 4137 1 All all DT cord-022526-j9kg00qf 4137 2 species specie NNS cord-022526-j9kg00qf 4137 3 of of IN cord-022526-j9kg00qf 4137 4 Epicauta Epicauta NNP cord-022526-j9kg00qf 4137 5 contain contain VBP cord-022526-j9kg00qf 4137 6 cantharidin cantharidin NNS cord-022526-j9kg00qf 4137 7 , , , cord-022526-j9kg00qf 4137 8 but but CC cord-022526-j9kg00qf 4137 9 some some DT cord-022526-j9kg00qf 4137 10 have have VBP cord-022526-j9kg00qf 4137 11 small small JJ cord-022526-j9kg00qf 4137 12 amounts amount NNS cord-022526-j9kg00qf 4137 13 . . . cord-022526-j9kg00qf 4138 1 Definitive definitive JJ cord-022526-j9kg00qf 4138 2 diagnosis diagnosis NN cord-022526-j9kg00qf 4138 3 requires require VBZ cord-022526-j9kg00qf 4138 4 the the DT cord-022526-j9kg00qf 4138 5 measurement measurement NN cord-022526-j9kg00qf 4138 6 of of IN cord-022526-j9kg00qf 4138 7 the the DT cord-022526-j9kg00qf 4138 8 cantharidin cantharidin JJ cord-022526-j9kg00qf 4138 9 concentration concentration NN cord-022526-j9kg00qf 4138 10 in in IN cord-022526-j9kg00qf 4138 11 gastric gastric JJ cord-022526-j9kg00qf 4138 12 or or CC cord-022526-j9kg00qf 4138 13 intestinal intestinal JJ cord-022526-j9kg00qf 4138 14 contents content NNS cord-022526-j9kg00qf 4138 15 and and CC cord-022526-j9kg00qf 4138 16 urine urine NN cord-022526-j9kg00qf 4138 17 . . . cord-022526-j9kg00qf 4139 1 183 183 CD cord-022526-j9kg00qf 4139 2 , , , cord-022526-j9kg00qf 4139 3 186 186 CD cord-022526-j9kg00qf 4139 4 Measurement Measurement NNP cord-022526-j9kg00qf 4139 5 of of IN cord-022526-j9kg00qf 4139 6 cantharidin cantharidin NNP cord-022526-j9kg00qf 4139 7 concentration concentration NN cord-022526-j9kg00qf 4139 8 in in IN cord-022526-j9kg00qf 4139 9 the the DT cord-022526-j9kg00qf 4139 10 beetles beetle NNS cord-022526-j9kg00qf 4139 11 is be VBZ cord-022526-j9kg00qf 4139 12 often often RB cord-022526-j9kg00qf 4139 13 done do VBN cord-022526-j9kg00qf 4139 14 but but CC cord-022526-j9kg00qf 4139 15 is be VBZ cord-022526-j9kg00qf 4139 16 not not RB cord-022526-j9kg00qf 4139 17 necessary necessary JJ cord-022526-j9kg00qf 4139 18 . . . cord-022526-j9kg00qf 4140 1 Arsenic arsenic NN cord-022526-j9kg00qf 4140 2 toxicosis toxicosis NN cord-022526-j9kg00qf 4140 3 is be VBZ cord-022526-j9kg00qf 4140 4 an an DT cord-022526-j9kg00qf 4140 5 unusual unusual JJ cord-022526-j9kg00qf 4140 6 cause cause NN cord-022526-j9kg00qf 4140 7 of of IN cord-022526-j9kg00qf 4140 8 diarrhea diarrhea NN cord-022526-j9kg00qf 4140 9 in in IN cord-022526-j9kg00qf 4140 10 horses horse NNS cord-022526-j9kg00qf 4140 11 , , , cord-022526-j9kg00qf 4140 12 resulting result VBG cord-022526-j9kg00qf 4140 13 from from IN cord-022526-j9kg00qf 4140 14 ingestion ingestion NN cord-022526-j9kg00qf 4140 15 of of IN cord-022526-j9kg00qf 4140 16 arsenic arsenic NN cord-022526-j9kg00qf 4140 17 - - HYPH cord-022526-j9kg00qf 4140 18 containing contain VBG cord-022526-j9kg00qf 4140 19 herbicides herbicide NNS cord-022526-j9kg00qf 4140 20 , , , cord-022526-j9kg00qf 4140 21 insecticides insecticide NNS cord-022526-j9kg00qf 4140 22 , , , cord-022526-j9kg00qf 4140 23 and and CC cord-022526-j9kg00qf 4140 24 other other JJ cord-022526-j9kg00qf 4140 25 pest pest NN cord-022526-j9kg00qf 4140 26 control control NN cord-022526-j9kg00qf 4140 27 products product NNS cord-022526-j9kg00qf 4140 28 contaminating contaminate VBG cord-022526-j9kg00qf 4140 29 water water NN cord-022526-j9kg00qf 4140 30 or or CC cord-022526-j9kg00qf 4140 31 roughage roughage NN cord-022526-j9kg00qf 4140 32 used use VBN cord-022526-j9kg00qf 4140 33 as as IN cord-022526-j9kg00qf 4140 34 a a DT cord-022526-j9kg00qf 4140 35 food food NN cord-022526-j9kg00qf 4140 36 source source NN cord-022526-j9kg00qf 4140 37 . . . cord-022526-j9kg00qf 4141 1 188 188 CD cord-022526-j9kg00qf 4142 1 The the DT cord-022526-j9kg00qf 4142 2 toxicity toxicity NN cord-022526-j9kg00qf 4142 3 of of IN cord-022526-j9kg00qf 4142 4 arsenic arsenic NN cord-022526-j9kg00qf 4142 5 depends depend VBZ cord-022526-j9kg00qf 4142 6 on on IN cord-022526-j9kg00qf 4142 7 the the DT cord-022526-j9kg00qf 4142 8 valence valence NN cord-022526-j9kg00qf 4142 9 of of IN cord-022526-j9kg00qf 4142 10 the the DT cord-022526-j9kg00qf 4142 11 element element NN cord-022526-j9kg00qf 4142 12 . . . cord-022526-j9kg00qf 4143 1 188 188 CD cord-022526-j9kg00qf 4143 2 , , , cord-022526-j9kg00qf 4143 3 189 189 CD cord-022526-j9kg00qf 4143 4 Arsenate Arsenate NNP cord-022526-j9kg00qf 4143 5 may may MD cord-022526-j9kg00qf 4143 6 be be VB cord-022526-j9kg00qf 4143 7 reduced reduce VBN cord-022526-j9kg00qf 4143 8 to to IN cord-022526-j9kg00qf 4143 9 arsenite arsenite JJ cord-022526-j9kg00qf 4143 10 in in IN cord-022526-j9kg00qf 4143 11 mammalian mammalian JJ cord-022526-j9kg00qf 4143 12 systems system NNS cord-022526-j9kg00qf 4143 13 , , , cord-022526-j9kg00qf 4143 14 and and CC cord-022526-j9kg00qf 4143 15 arsenite arsenite NNP cord-022526-j9kg00qf 4143 16 is be VBZ cord-022526-j9kg00qf 4143 17 thought think VBN cord-022526-j9kg00qf 4143 18 to to TO cord-022526-j9kg00qf 4143 19 be be VB cord-022526-j9kg00qf 4143 20 more more RBR cord-022526-j9kg00qf 4143 21 toxic toxic JJ cord-022526-j9kg00qf 4143 22 than than IN cord-022526-j9kg00qf 4143 23 arsenate arsenate NN cord-022526-j9kg00qf 4143 24 and and CC cord-022526-j9kg00qf 4143 25 less less RBR cord-022526-j9kg00qf 4143 26 rapidly rapidly RB cord-022526-j9kg00qf 4143 27 excreted excrete VBN cord-022526-j9kg00qf 4143 28 in in IN cord-022526-j9kg00qf 4143 29 urine urine NN cord-022526-j9kg00qf 4143 30 . . . cord-022526-j9kg00qf 4144 1 Arsenate arsenate NN cord-022526-j9kg00qf 4144 2 and and CC cord-022526-j9kg00qf 4144 3 arsenite arsenite JJ cord-022526-j9kg00qf 4144 4 uncouple uncouple VBP cord-022526-j9kg00qf 4144 5 oxidative oxidative JJ cord-022526-j9kg00qf 4144 6 phosphorylation phosphorylation NN cord-022526-j9kg00qf 4144 7 , , , cord-022526-j9kg00qf 4144 8 leading lead VBG cord-022526-j9kg00qf 4144 9 to to IN cord-022526-j9kg00qf 4144 10 breakdown breakdown NN cord-022526-j9kg00qf 4144 11 of of IN cord-022526-j9kg00qf 4144 12 energy energy NN cord-022526-j9kg00qf 4144 13 metabolism metabolism NN cord-022526-j9kg00qf 4144 14 in in IN cord-022526-j9kg00qf 4144 15 the the DT cord-022526-j9kg00qf 4144 16 cells cell NNS cord-022526-j9kg00qf 4144 17 of of IN cord-022526-j9kg00qf 4144 18 many many JJ cord-022526-j9kg00qf 4144 19 tissues tissue NNS cord-022526-j9kg00qf 4144 20 . . . cord-022526-j9kg00qf 4145 1 189 189 CD cord-022526-j9kg00qf 4146 1 Widespread widespread JJ cord-022526-j9kg00qf 4146 2 cellular cellular JJ cord-022526-j9kg00qf 4146 3 injury injury NN cord-022526-j9kg00qf 4146 4 and and CC cord-022526-j9kg00qf 4146 5 death death NN cord-022526-j9kg00qf 4146 6 occur occur VBP cord-022526-j9kg00qf 4146 7 rapidly rapidly RB cord-022526-j9kg00qf 4146 8 during during IN cord-022526-j9kg00qf 4146 9 acute acute JJ cord-022526-j9kg00qf 4146 10 arsenic arsenic NN cord-022526-j9kg00qf 4146 11 toxicosis toxicosis NN cord-022526-j9kg00qf 4146 12 . . . cord-022526-j9kg00qf 4147 1 Multiorgan multiorgan JJ cord-022526-j9kg00qf 4147 2 failure failure NN cord-022526-j9kg00qf 4147 3 usually usually RB cord-022526-j9kg00qf 4147 4 results result VBZ cord-022526-j9kg00qf 4147 5 . . . cord-022526-j9kg00qf 4148 1 In in IN cord-022526-j9kg00qf 4148 2 fact fact NN cord-022526-j9kg00qf 4148 3 , , , cord-022526-j9kg00qf 4148 4 cardiomyopathy cardiomyopathy NN cord-022526-j9kg00qf 4148 5 and and CC cord-022526-j9kg00qf 4148 6 pulmonary pulmonary JJ cord-022526-j9kg00qf 4148 7 disease disease NN cord-022526-j9kg00qf 4148 8 are be VBP cord-022526-j9kg00qf 4148 9 common common JJ cord-022526-j9kg00qf 4148 10 causes cause NNS cord-022526-j9kg00qf 4148 11 of of IN cord-022526-j9kg00qf 4148 12 death death NN cord-022526-j9kg00qf 4148 13 in in IN cord-022526-j9kg00qf 4148 14 human human JJ cord-022526-j9kg00qf 4148 15 beings being NNS cord-022526-j9kg00qf 4148 16 . . . cord-022526-j9kg00qf 4149 1 190 190 CD cord-022526-j9kg00qf 4149 2 Damage damage NN cord-022526-j9kg00qf 4149 3 to to IN cord-022526-j9kg00qf 4149 4 the the DT cord-022526-j9kg00qf 4149 5 large large JJ cord-022526-j9kg00qf 4149 6 intestine intestine NN cord-022526-j9kg00qf 4149 7 is be VBZ cord-022526-j9kg00qf 4149 8 probably probably RB cord-022526-j9kg00qf 4149 9 caused cause VBN cord-022526-j9kg00qf 4149 10 in in IN cord-022526-j9kg00qf 4149 11 part part NN cord-022526-j9kg00qf 4149 12 by by IN cord-022526-j9kg00qf 4149 13 direct direct JJ cord-022526-j9kg00qf 4149 14 cellular cellular JJ cord-022526-j9kg00qf 4149 15 toxicity toxicity NN cord-022526-j9kg00qf 4149 16 and and CC cord-022526-j9kg00qf 4149 17 corrosion corrosion NN cord-022526-j9kg00qf 4149 18 by by IN cord-022526-j9kg00qf 4149 19 the the DT cord-022526-j9kg00qf 4149 20 compound compound NN cord-022526-j9kg00qf 4149 21 . . . cord-022526-j9kg00qf 4150 1 However however RB cord-022526-j9kg00qf 4150 2 , , , cord-022526-j9kg00qf 4150 3 vasculitis vasculitis NN cord-022526-j9kg00qf 4150 4 is be VBZ cord-022526-j9kg00qf 4150 5 a a DT cord-022526-j9kg00qf 4150 6 hallmark hallmark NN cord-022526-j9kg00qf 4150 7 of of IN cord-022526-j9kg00qf 4150 8 the the DT cord-022526-j9kg00qf 4150 9 disease disease NN cord-022526-j9kg00qf 4150 10 in in IN cord-022526-j9kg00qf 4150 11 human human JJ cord-022526-j9kg00qf 4150 12 beings being NNS cord-022526-j9kg00qf 4150 13 and and CC cord-022526-j9kg00qf 4150 14 horses horse NNS cord-022526-j9kg00qf 4150 15 and and CC cord-022526-j9kg00qf 4150 16 is be VBZ cord-022526-j9kg00qf 4150 17 thought think VBN cord-022526-j9kg00qf 4150 18 to to TO cord-022526-j9kg00qf 4150 19 be be VB cord-022526-j9kg00qf 4150 20 the the DT cord-022526-j9kg00qf 4150 21 most most RBS cord-022526-j9kg00qf 4150 22 important important JJ cord-022526-j9kg00qf 4150 23 mechanism mechanism NN cord-022526-j9kg00qf 4150 24 of of IN cord-022526-j9kg00qf 4150 25 large large JJ cord-022526-j9kg00qf 4150 26 intestinal intestinal JJ cord-022526-j9kg00qf 4150 27 disease disease NN cord-022526-j9kg00qf 4150 28 in in IN cord-022526-j9kg00qf 4150 29 human human JJ cord-022526-j9kg00qf 4150 30 beings being NNS cord-022526-j9kg00qf 4150 31 . . . cord-022526-j9kg00qf 4151 1 181 181 CD cord-022526-j9kg00qf 4151 2 , , , cord-022526-j9kg00qf 4151 3 191 191 CD cord-022526-j9kg00qf 4151 4 Acute acute JJ cord-022526-j9kg00qf 4151 5 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4151 6 colitis colitis NN cord-022526-j9kg00qf 4151 7 is be VBZ cord-022526-j9kg00qf 4151 8 a a DT cord-022526-j9kg00qf 4151 9 feature feature NN cord-022526-j9kg00qf 4151 10 of of IN cord-022526-j9kg00qf 4151 11 arsenic arsenic NN cord-022526-j9kg00qf 4151 12 toxicosis toxicosis NN cord-022526-j9kg00qf 4151 13 , , , cord-022526-j9kg00qf 4151 14 with with IN cord-022526-j9kg00qf 4151 15 severe severe JJ cord-022526-j9kg00qf 4151 16 mural mural NN cord-022526-j9kg00qf 4151 17 edema edema NN cord-022526-j9kg00qf 4151 18 and and CC cord-022526-j9kg00qf 4151 19 mucosal mucosal JJ cord-022526-j9kg00qf 4151 20 ulceration ulceration NN cord-022526-j9kg00qf 4151 21 . . . cord-022526-j9kg00qf 4152 1 188 188 CD cord-022526-j9kg00qf 4153 1 Profuse profuse JJ cord-022526-j9kg00qf 4153 2 , , , cord-022526-j9kg00qf 4153 3 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4153 4 diarrhea diarrhea NN cord-022526-j9kg00qf 4153 5 and and CC cord-022526-j9kg00qf 4153 6 abdominal abdominal JJ cord-022526-j9kg00qf 4153 7 pain pain NN cord-022526-j9kg00qf 4153 8 result result NN cord-022526-j9kg00qf 4153 9 . . . cord-022526-j9kg00qf 4154 1 Chronic chronic JJ cord-022526-j9kg00qf 4154 2 arsenic arsenic NN cord-022526-j9kg00qf 4154 3 toxicity toxicity NN cord-022526-j9kg00qf 4154 4 can can MD cord-022526-j9kg00qf 4154 5 occur occur VB cord-022526-j9kg00qf 4154 6 but but CC cord-022526-j9kg00qf 4154 7 appears appear VBZ cord-022526-j9kg00qf 4154 8 to to TO cord-022526-j9kg00qf 4154 9 be be VB cord-022526-j9kg00qf 4154 10 rare rare JJ cord-022526-j9kg00qf 4154 11 in in IN cord-022526-j9kg00qf 4154 12 horses horse NNS cord-022526-j9kg00qf 4154 13 . . . cord-022526-j9kg00qf 4155 1 Acute acute JJ cord-022526-j9kg00qf 4155 2 depression depression NN cord-022526-j9kg00qf 4155 3 , , , cord-022526-j9kg00qf 4155 4 weakness weakness NN cord-022526-j9kg00qf 4155 5 , , , cord-022526-j9kg00qf 4155 6 abdominal abdominal JJ cord-022526-j9kg00qf 4155 7 pain pain NN cord-022526-j9kg00qf 4155 8 , , , cord-022526-j9kg00qf 4155 9 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4155 10 diarrhea diarrhea NN cord-022526-j9kg00qf 4155 11 , , , cord-022526-j9kg00qf 4155 12 and and CC cord-022526-j9kg00qf 4155 13 shock shock NN cord-022526-j9kg00qf 4155 14 are be VBP cord-022526-j9kg00qf 4155 15 characteristic characteristic JJ cord-022526-j9kg00qf 4155 16 of of IN cord-022526-j9kg00qf 4155 17 acute acute JJ cord-022526-j9kg00qf 4155 18 arsenic arsenic NN cord-022526-j9kg00qf 4155 19 toxicosis toxicosis NN cord-022526-j9kg00qf 4155 20 in in IN cord-022526-j9kg00qf 4155 21 horses horse NNS cord-022526-j9kg00qf 4155 22 . . . cord-022526-j9kg00qf 4156 1 Death death NN cord-022526-j9kg00qf 4156 2 may may MD cord-022526-j9kg00qf 4156 3 occur occur VB cord-022526-j9kg00qf 4156 4 before before IN cord-022526-j9kg00qf 4156 5 diarrhea diarrhea NN cord-022526-j9kg00qf 4156 6 is be VBZ cord-022526-j9kg00qf 4156 7 evident evident JJ cord-022526-j9kg00qf 4156 8 . . . cord-022526-j9kg00qf 4157 1 Initial initial JJ cord-022526-j9kg00qf 4157 2 clinical clinical JJ cord-022526-j9kg00qf 4157 3 signs sign NNS cord-022526-j9kg00qf 4157 4 may may MD cord-022526-j9kg00qf 4157 5 be be VB cord-022526-j9kg00qf 4157 6 difficult difficult JJ cord-022526-j9kg00qf 4157 7 to to TO cord-022526-j9kg00qf 4157 8 distinguish distinguish VB cord-022526-j9kg00qf 4157 9 from from IN cord-022526-j9kg00qf 4157 10 other other JJ cord-022526-j9kg00qf 4157 11 peracute peracute NN cord-022526-j9kg00qf 4157 12 forms form NNS cord-022526-j9kg00qf 4157 13 of of IN cord-022526-j9kg00qf 4157 14 colitis colitis NN cord-022526-j9kg00qf 4157 15 and and CC cord-022526-j9kg00qf 4157 16 are be VBP cord-022526-j9kg00qf 4157 17 related relate VBN cord-022526-j9kg00qf 4157 18 to to IN cord-022526-j9kg00qf 4157 19 endotoxic endotoxic JJ cord-022526-j9kg00qf 4157 20 shock shock NN cord-022526-j9kg00qf 4157 21 , , , cord-022526-j9kg00qf 4157 22 metabolic metabolic JJ cord-022526-j9kg00qf 4157 23 disturbances disturbance NNS cord-022526-j9kg00qf 4157 24 , , , cord-022526-j9kg00qf 4157 25 and and CC cord-022526-j9kg00qf 4157 26 dehydration dehydration NN cord-022526-j9kg00qf 4157 27 . . . cord-022526-j9kg00qf 4158 1 Later later RB cord-022526-j9kg00qf 4158 2 , , , cord-022526-j9kg00qf 4158 3 cardiac cardiac NN cord-022526-j9kg00qf 4158 4 arrhythmias arrhythmia NNS cord-022526-j9kg00qf 4158 5 , , , cord-022526-j9kg00qf 4158 6 pulmonary pulmonary JJ cord-022526-j9kg00qf 4158 7 edema edema NN cord-022526-j9kg00qf 4158 8 , , , cord-022526-j9kg00qf 4158 9 acute acute JJ cord-022526-j9kg00qf 4158 10 renal renal JJ cord-022526-j9kg00qf 4158 11 failure failure NN cord-022526-j9kg00qf 4158 12 , , , cord-022526-j9kg00qf 4158 13 and and CC cord-022526-j9kg00qf 4158 14 neurologic neurologic JJ cord-022526-j9kg00qf 4158 15 deficits deficit NNS cord-022526-j9kg00qf 4158 16 ( ( -LRB- cord-022526-j9kg00qf 4158 17 ataxia ataxia NN cord-022526-j9kg00qf 4158 18 and and CC cord-022526-j9kg00qf 4158 19 stupor stupor NN cord-022526-j9kg00qf 4158 20 ) ) -RRB- cord-022526-j9kg00qf 4158 21 may may MD cord-022526-j9kg00qf 4158 22 develop develop VB cord-022526-j9kg00qf 4158 23 . . . cord-022526-j9kg00qf 4159 1 188 188 CD cord-022526-j9kg00qf 4159 2 One one CD cord-022526-j9kg00qf 4159 3 may may MD cord-022526-j9kg00qf 4159 4 observe observe VB cord-022526-j9kg00qf 4159 5 anuria anuria NN cord-022526-j9kg00qf 4159 6 or or CC cord-022526-j9kg00qf 4159 7 polyuria polyuria NN cord-022526-j9kg00qf 4159 8 . . . cord-022526-j9kg00qf 4160 1 Hemolytic hemolytic JJ cord-022526-j9kg00qf 4160 2 anemia anemia NN cord-022526-j9kg00qf 4160 3 caused cause VBN cord-022526-j9kg00qf 4160 4 by by IN cord-022526-j9kg00qf 4160 5 preferential preferential JJ cord-022526-j9kg00qf 4160 6 binding binding NN cord-022526-j9kg00qf 4160 7 of of IN cord-022526-j9kg00qf 4160 8 arsenic arsenic NN cord-022526-j9kg00qf 4160 9 compounds compound NNS cord-022526-j9kg00qf 4160 10 to to IN cord-022526-j9kg00qf 4160 11 red red JJ cord-022526-j9kg00qf 4160 12 blood blood NN cord-022526-j9kg00qf 4160 13 cells cell NNS cord-022526-j9kg00qf 4160 14 is be VBZ cord-022526-j9kg00qf 4160 15 a a DT cord-022526-j9kg00qf 4160 16 feature feature NN cord-022526-j9kg00qf 4160 17 of of IN cord-022526-j9kg00qf 4160 18 arsenic arsenic NN cord-022526-j9kg00qf 4160 19 poisoning poisoning NN cord-022526-j9kg00qf 4160 20 in in IN cord-022526-j9kg00qf 4160 21 human human JJ cord-022526-j9kg00qf 4160 22 beings being NNS cord-022526-j9kg00qf 4160 23 . . . cord-022526-j9kg00qf 4161 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 4161 2 abnormalities abnormality NNS cord-022526-j9kg00qf 4161 3 may may MD cord-022526-j9kg00qf 4161 4 be be VB cord-022526-j9kg00qf 4161 5 apparent apparent JJ cord-022526-j9kg00qf 4161 6 after after IN cord-022526-j9kg00qf 4161 7 the the DT cord-022526-j9kg00qf 4161 8 peracute peracute NN cord-022526-j9kg00qf 4161 9 stages stage NNS cord-022526-j9kg00qf 4161 10 from from IN cord-022526-j9kg00qf 4161 11 injury injury NN cord-022526-j9kg00qf 4161 12 to to IN cord-022526-j9kg00qf 4161 13 bone bone NN cord-022526-j9kg00qf 4161 14 marrow marrow NN cord-022526-j9kg00qf 4161 15 cells cell NNS cord-022526-j9kg00qf 4161 16 and and CC cord-022526-j9kg00qf 4161 17 ongoing ongoing JJ cord-022526-j9kg00qf 4161 18 hemolysis hemolysis NN cord-022526-j9kg00qf 4161 19 . . . cord-022526-j9kg00qf 4162 1 Leukopenia leukopenia NN cord-022526-j9kg00qf 4162 2 and and CC cord-022526-j9kg00qf 4162 3 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 4162 4 have have VBP cord-022526-j9kg00qf 4162 5 been be VBN cord-022526-j9kg00qf 4162 6 described describe VBN cord-022526-j9kg00qf 4162 7 in in IN cord-022526-j9kg00qf 4162 8 human human JJ cord-022526-j9kg00qf 4162 9 patients patient NNS cord-022526-j9kg00qf 4162 10 . . . cord-022526-j9kg00qf 4163 1 190 190 CD cord-022526-j9kg00qf 4163 2 Serum serum NN cord-022526-j9kg00qf 4163 3 biochemical biochemical JJ cord-022526-j9kg00qf 4163 4 analysis analysis NN cord-022526-j9kg00qf 4163 5 may may MD cord-022526-j9kg00qf 4163 6 reveal reveal VB cord-022526-j9kg00qf 4163 7 azotemia azotemia NN cord-022526-j9kg00qf 4163 8 , , , cord-022526-j9kg00qf 4163 9 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 4163 10 enzyme enzyme NN cord-022526-j9kg00qf 4163 11 activities activity NNS cord-022526-j9kg00qf 4163 12 higher high JJR cord-022526-j9kg00qf 4163 13 than than IN cord-022526-j9kg00qf 4163 14 generally generally RB cord-022526-j9kg00qf 4163 15 attributed attribute VBN cord-022526-j9kg00qf 4163 16 to to IN cord-022526-j9kg00qf 4163 17 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4163 18 , , , cord-022526-j9kg00qf 4163 19 and and CC cord-022526-j9kg00qf 4163 20 elevated elevate VBN cord-022526-j9kg00qf 4163 21 creatine creatine NN cord-022526-j9kg00qf 4163 22 kinase kinase NN cord-022526-j9kg00qf 4163 23 activity activity NN cord-022526-j9kg00qf 4163 24 . . . cord-022526-j9kg00qf 4164 1 188 188 CD cord-022526-j9kg00qf 4164 2 Urine urine NN cord-022526-j9kg00qf 4164 3 specific specific JJ cord-022526-j9kg00qf 4164 4 gravity gravity NN cord-022526-j9kg00qf 4164 5 may may MD cord-022526-j9kg00qf 4164 6 be be VB cord-022526-j9kg00qf 4164 7 in in IN cord-022526-j9kg00qf 4164 8 the the DT cord-022526-j9kg00qf 4164 9 isosthenuric isosthenuric JJ cord-022526-j9kg00qf 4164 10 range range NN cord-022526-j9kg00qf 4164 11 , , , cord-022526-j9kg00qf 4164 12 with with IN cord-022526-j9kg00qf 4164 13 hematuria hematuria NN cord-022526-j9kg00qf 4164 14 , , , cord-022526-j9kg00qf 4164 15 cylindruria cylindruria NNP cord-022526-j9kg00qf 4164 16 , , , cord-022526-j9kg00qf 4164 17 and and CC cord-022526-j9kg00qf 4164 18 proteinuria proteinuria NN cord-022526-j9kg00qf 4164 19 evident evident JJ cord-022526-j9kg00qf 4164 20 by by IN cord-022526-j9kg00qf 4164 21 urinalysis urinalysis NN cord-022526-j9kg00qf 4164 22 . . . cord-022526-j9kg00qf 4165 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 4165 2 may may MD cord-022526-j9kg00qf 4165 3 be be VB cord-022526-j9kg00qf 4165 4 possible possible JJ cord-022526-j9kg00qf 4165 5 by by IN cord-022526-j9kg00qf 4165 6 measuring measure VBG cord-022526-j9kg00qf 4165 7 blood blood NN cord-022526-j9kg00qf 4165 8 and and CC cord-022526-j9kg00qf 4165 9 urine urine NN cord-022526-j9kg00qf 4165 10 arsenic arsenic NN cord-022526-j9kg00qf 4165 11 concentration concentration NN cord-022526-j9kg00qf 4165 12 , , , cord-022526-j9kg00qf 4165 13 but but CC cord-022526-j9kg00qf 4165 14 these these DT cord-022526-j9kg00qf 4165 15 tests test NNS cord-022526-j9kg00qf 4165 16 may may MD cord-022526-j9kg00qf 4165 17 not not RB cord-022526-j9kg00qf 4165 18 be be VB cord-022526-j9kg00qf 4165 19 diagnostic diagnostic JJ cord-022526-j9kg00qf 4165 20 . . . cord-022526-j9kg00qf 4166 1 Postmortem postmortem JJ cord-022526-j9kg00qf 4166 2 diagnosis diagnosis NN cord-022526-j9kg00qf 4166 3 is be VBZ cord-022526-j9kg00qf 4166 4 by by IN cord-022526-j9kg00qf 4166 5 measuring measure VBG cord-022526-j9kg00qf 4166 6 the the DT cord-022526-j9kg00qf 4166 7 arsenic arsenic NN cord-022526-j9kg00qf 4166 8 concentration concentration NN cord-022526-j9kg00qf 4166 9 in in IN cord-022526-j9kg00qf 4166 10 liver liver NN cord-022526-j9kg00qf 4166 11 and and CC cord-022526-j9kg00qf 4166 12 kidney kidney NN cord-022526-j9kg00qf 4166 13 samples sample NNS cord-022526-j9kg00qf 4166 14 . . . cord-022526-j9kg00qf 4167 1 188 188 CD cord-022526-j9kg00qf 4167 2 History history NN cord-022526-j9kg00qf 4167 3 of of IN cord-022526-j9kg00qf 4167 4 exposure exposure NN cord-022526-j9kg00qf 4167 5 and and CC cord-022526-j9kg00qf 4167 6 clinical clinical JJ cord-022526-j9kg00qf 4167 7 signs sign NNS cord-022526-j9kg00qf 4167 8 remain remain VBP cord-022526-j9kg00qf 4167 9 the the DT cord-022526-j9kg00qf 4167 10 primary primary JJ cord-022526-j9kg00qf 4167 11 means mean NNS cord-022526-j9kg00qf 4167 12 of of IN cord-022526-j9kg00qf 4167 13 diagnosis diagnosis NN cord-022526-j9kg00qf 4167 14 . . . cord-022526-j9kg00qf 4168 1 Other other JJ cord-022526-j9kg00qf 4168 2 disorders disorder NNS cord-022526-j9kg00qf 4168 3 associated associate VBN cord-022526-j9kg00qf 4168 4 with with IN cord-022526-j9kg00qf 4168 5 diarrhea diarrhea NN cord-022526-j9kg00qf 4168 6 in in IN cord-022526-j9kg00qf 4168 7 adult adult NN cord-022526-j9kg00qf 4168 8 horses horse NNS cord-022526-j9kg00qf 4168 9 include include VBP cord-022526-j9kg00qf 4168 10 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4168 11 , , , cord-022526-j9kg00qf 4168 12 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4168 13 overload overload NN cord-022526-j9kg00qf 4168 14 , , , cord-022526-j9kg00qf 4168 15 and and CC cord-022526-j9kg00qf 4168 16 sand sand NN cord-022526-j9kg00qf 4168 17 enteropathy enteropathy NNP cord-022526-j9kg00qf 4168 18 . . . cord-022526-j9kg00qf 4169 1 Careful careful JJ cord-022526-j9kg00qf 4169 2 evaluation evaluation NN cord-022526-j9kg00qf 4169 3 of of IN cord-022526-j9kg00qf 4169 4 history history NN cord-022526-j9kg00qf 4169 5 , , , cord-022526-j9kg00qf 4169 6 environment environment NN cord-022526-j9kg00qf 4169 7 , , , cord-022526-j9kg00qf 4169 8 and and CC cord-022526-j9kg00qf 4169 9 management management NN cord-022526-j9kg00qf 4169 10 will will MD cord-022526-j9kg00qf 4169 11 assist assist VB cord-022526-j9kg00qf 4169 12 the the DT cord-022526-j9kg00qf 4169 13 clinician clinician NN cord-022526-j9kg00qf 4169 14 in in IN cord-022526-j9kg00qf 4169 15 arriving arrive VBG cord-022526-j9kg00qf 4169 16 at at IN cord-022526-j9kg00qf 4169 17 an an DT cord-022526-j9kg00qf 4169 18 accurate accurate JJ cord-022526-j9kg00qf 4169 19 diagnosis diagnosis NN cord-022526-j9kg00qf 4169 20 . . . cord-022526-j9kg00qf 4170 1 Severe severe JJ cord-022526-j9kg00qf 4170 2 intestinal intestinal JJ cord-022526-j9kg00qf 4170 3 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4170 4 is be VBZ cord-022526-j9kg00qf 4170 5 a a DT cord-022526-j9kg00qf 4170 6 syndrome syndrome NN cord-022526-j9kg00qf 4170 7 in in IN cord-022526-j9kg00qf 4170 8 horses horse NNS cord-022526-j9kg00qf 4170 9 characterized characterize VBN cord-022526-j9kg00qf 4170 10 by by IN cord-022526-j9kg00qf 4170 11 peracute peracute NNP cord-022526-j9kg00qf 4170 12 , , , cord-022526-j9kg00qf 4170 13 rapidly rapidly RB cord-022526-j9kg00qf 4170 14 fatal fatal JJ cord-022526-j9kg00qf 4170 15 colitis colitis NN cord-022526-j9kg00qf 4170 16 . . . cord-022526-j9kg00qf 4171 1 192 192 CD cord-022526-j9kg00qf 4172 1 The the DT cord-022526-j9kg00qf 4172 2 severe severe JJ cord-022526-j9kg00qf 4172 3 syndrome syndrome NN cord-022526-j9kg00qf 4172 4 is be VBZ cord-022526-j9kg00qf 4172 5 clinically clinically RB cord-022526-j9kg00qf 4172 6 and and CC cord-022526-j9kg00qf 4172 7 pathologically pathologically RB cord-022526-j9kg00qf 4172 8 similar similar JJ cord-022526-j9kg00qf 4172 9 to to IN cord-022526-j9kg00qf 4172 10 other other JJ cord-022526-j9kg00qf 4172 11 known know VBN cord-022526-j9kg00qf 4172 12 causes cause NNS cord-022526-j9kg00qf 4172 13 of of IN cord-022526-j9kg00qf 4172 14 peracute peracute NN cord-022526-j9kg00qf 4172 15 colitis colitis NN cord-022526-j9kg00qf 4172 16 , , , cord-022526-j9kg00qf 4172 17 such such JJ cord-022526-j9kg00qf 4172 18 as as IN cord-022526-j9kg00qf 4172 19 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4172 20 , , , cord-022526-j9kg00qf 4172 21 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4172 22 , , , cord-022526-j9kg00qf 4172 23 and and CC cord-022526-j9kg00qf 4172 24 antibiotic antibiotic NN cord-022526-j9kg00qf 4172 25 - - HYPH cord-022526-j9kg00qf 4172 26 associated associated JJ cord-022526-j9kg00qf 4172 27 diarrhea diarrhea NN cord-022526-j9kg00qf 4172 28 . . . cord-022526-j9kg00qf 4173 1 Some some DT cord-022526-j9kg00qf 4173 2 cases case NNS cord-022526-j9kg00qf 4173 3 are be VBP cord-022526-j9kg00qf 4173 4 less less RBR cord-022526-j9kg00qf 4173 5 severe severe JJ cord-022526-j9kg00qf 4173 6 and and CC cord-022526-j9kg00qf 4173 7 manifest manifest JJ cord-022526-j9kg00qf 4173 8 as as RB cord-022526-j9kg00qf 4173 9 mild mild JJ cord-022526-j9kg00qf 4173 10 to to IN cord-022526-j9kg00qf 4173 11 moderate moderate JJ cord-022526-j9kg00qf 4173 12 diarrhea diarrhea NN cord-022526-j9kg00qf 4173 13 or or CC cord-022526-j9kg00qf 4173 14 colic colic NN cord-022526-j9kg00qf 4173 15 . . . cord-022526-j9kg00qf 4174 1 An an DT cord-022526-j9kg00qf 4174 2 IgE ige NN cord-022526-j9kg00qf 4174 3 - - HYPH cord-022526-j9kg00qf 4174 4 mediated mediate VBN cord-022526-j9kg00qf 4174 5 type type NN cord-022526-j9kg00qf 4174 6 I -PRON- PRP cord-022526-j9kg00qf 4174 7 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 4174 8 or or CC cord-022526-j9kg00qf 4174 9 an an DT cord-022526-j9kg00qf 4174 10 IgE ige JJ cord-022526-j9kg00qf 4174 11 - - HYPH cord-022526-j9kg00qf 4174 12 independent independent JJ cord-022526-j9kg00qf 4174 13 anaphylactoid anaphylactoid NNP cord-022526-j9kg00qf 4174 14 reaction reaction NN cord-022526-j9kg00qf 4174 15 can can MD cord-022526-j9kg00qf 4174 16 produce produce VB cord-022526-j9kg00qf 4174 17 the the DT cord-022526-j9kg00qf 4174 18 syndrome syndrome NN cord-022526-j9kg00qf 4174 19 of of IN cord-022526-j9kg00qf 4174 20 intestinal intestinal JJ cord-022526-j9kg00qf 4174 21 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4174 22 . . . cord-022526-j9kg00qf 4175 1 193 193 CD cord-022526-j9kg00qf 4175 2 , , , cord-022526-j9kg00qf 4175 3 194 194 CD cord-022526-j9kg00qf 4175 4 Local local JJ cord-022526-j9kg00qf 4175 5 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4175 6 exposure exposure NN cord-022526-j9kg00qf 4175 7 to to IN cord-022526-j9kg00qf 4175 8 a a DT cord-022526-j9kg00qf 4175 9 food food NN cord-022526-j9kg00qf 4175 10 , , , cord-022526-j9kg00qf 4175 11 environmental environmental JJ cord-022526-j9kg00qf 4175 12 contaminant contaminant NN cord-022526-j9kg00qf 4175 13 , , , cord-022526-j9kg00qf 4175 14 drug drug NN cord-022526-j9kg00qf 4175 15 , , , cord-022526-j9kg00qf 4175 16 or or CC cord-022526-j9kg00qf 4175 17 other other JJ cord-022526-j9kg00qf 4175 18 allergen allergen NN cord-022526-j9kg00qf 4175 19 usually usually RB cord-022526-j9kg00qf 4175 20 induces induce VBZ cord-022526-j9kg00qf 4175 21 intestinal intestinal JJ cord-022526-j9kg00qf 4175 22 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4175 23 , , , cord-022526-j9kg00qf 4175 24 193 193 CD cord-022526-j9kg00qf 4175 25 , , , cord-022526-j9kg00qf 4175 26 195 195 CD cord-022526-j9kg00qf 4175 27 but but CC cord-022526-j9kg00qf 4175 28 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4175 29 also also RB cord-022526-j9kg00qf 4175 30 may may MD cord-022526-j9kg00qf 4175 31 occur occur VB cord-022526-j9kg00qf 4175 32 with with IN cord-022526-j9kg00qf 4175 33 systemic systemic JJ cord-022526-j9kg00qf 4175 34 exposure exposure NN cord-022526-j9kg00qf 4175 35 to to IN cord-022526-j9kg00qf 4175 36 an an DT cord-022526-j9kg00qf 4175 37 allergen allergen NN cord-022526-j9kg00qf 4175 38 . . . cord-022526-j9kg00qf 4176 1 [ [ -LRB- cord-022526-j9kg00qf 4176 2 196 196 CD cord-022526-j9kg00qf 4176 3 ] ] -RRB- cord-022526-j9kg00qf 4176 4 [ [ -LRB- cord-022526-j9kg00qf 4176 5 197 197 CD cord-022526-j9kg00qf 4176 6 ] ] -RRB- cord-022526-j9kg00qf 4177 1 [ [ -LRB- cord-022526-j9kg00qf 4177 2 198 198 CD cord-022526-j9kg00qf 4177 3 ] ] -RRB- cord-022526-j9kg00qf 4178 1 [ [ -LRB- cord-022526-j9kg00qf 4178 2 199 199 CD cord-022526-j9kg00qf 4178 3 ] ] -RRB- cord-022526-j9kg00qf 4179 1 Massive massive JJ cord-022526-j9kg00qf 4179 2 mast mast JJ cord-022526-j9kg00qf 4179 3 cell cell NN cord-022526-j9kg00qf 4179 4 degranulation degranulation NN cord-022526-j9kg00qf 4179 5 , , , cord-022526-j9kg00qf 4179 6 secretion secretion NN cord-022526-j9kg00qf 4179 7 of of IN cord-022526-j9kg00qf 4179 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 4179 9 mediators mediator NNS cord-022526-j9kg00qf 4179 10 , , , cord-022526-j9kg00qf 4179 11 and and CC cord-022526-j9kg00qf 4179 12 activation activation NN cord-022526-j9kg00qf 4179 13 of of IN cord-022526-j9kg00qf 4179 14 enteric enteric JJ cord-022526-j9kg00qf 4179 15 neural neural JJ cord-022526-j9kg00qf 4179 16 reflexes reflex NNS cord-022526-j9kg00qf 4179 17 in in IN cord-022526-j9kg00qf 4179 18 the the DT cord-022526-j9kg00qf 4179 19 intestine intestine NN cord-022526-j9kg00qf 4179 20 causes cause VBZ cord-022526-j9kg00qf 4179 21 profound profound JJ cord-022526-j9kg00qf 4179 22 alterations alteration NNS cord-022526-j9kg00qf 4179 23 in in IN cord-022526-j9kg00qf 4179 24 blood blood NN cord-022526-j9kg00qf 4179 25 flow flow NN cord-022526-j9kg00qf 4179 26 , , , cord-022526-j9kg00qf 4179 27 increased increase VBD cord-022526-j9kg00qf 4179 28 vascular vascular JJ cord-022526-j9kg00qf 4179 29 permeability permeability NN cord-022526-j9kg00qf 4179 30 and and CC cord-022526-j9kg00qf 4179 31 interstitial interstitial JJ cord-022526-j9kg00qf 4179 32 edema edema NN cord-022526-j9kg00qf 4179 33 , , , cord-022526-j9kg00qf 4179 34 recruitment recruitment NN cord-022526-j9kg00qf 4179 35 of of IN cord-022526-j9kg00qf 4179 36 neutrophils neutrophil NNS cord-022526-j9kg00qf 4179 37 , , , cord-022526-j9kg00qf 4179 38 altered alter VBN cord-022526-j9kg00qf 4179 39 motility motility NN cord-022526-j9kg00qf 4179 40 , , , cord-022526-j9kg00qf 4179 41 mucosal mucosal JJ cord-022526-j9kg00qf 4179 42 injury injury NN cord-022526-j9kg00qf 4179 43 , , , cord-022526-j9kg00qf 4179 44 absorption absorption NN cord-022526-j9kg00qf 4179 45 of of IN cord-022526-j9kg00qf 4179 46 microbial microbial JJ cord-022526-j9kg00qf 4179 47 products product NNS cord-022526-j9kg00qf 4179 48 , , , cord-022526-j9kg00qf 4179 49 and and CC cord-022526-j9kg00qf 4179 50 mucosal mucosal JJ cord-022526-j9kg00qf 4179 51 hypersecretion hypersecretion NN cord-022526-j9kg00qf 4179 52 . . . cord-022526-j9kg00qf 4180 1 [ [ -LRB- cord-022526-j9kg00qf 4180 2 200 200 CD cord-022526-j9kg00qf 4180 3 ] ] -RRB- cord-022526-j9kg00qf 4180 4 [ [ -LRB- cord-022526-j9kg00qf 4180 5 201 201 CD cord-022526-j9kg00qf 4180 6 ] ] -RRB- cord-022526-j9kg00qf 4180 7 [ [ -LRB- cord-022526-j9kg00qf 4180 8 202 202 CD cord-022526-j9kg00qf 4180 9 ] ] -RRB- cord-022526-j9kg00qf 4180 10 [ [ -LRB- cord-022526-j9kg00qf 4180 11 203 203 CD cord-022526-j9kg00qf 4180 12 ] ] -RRB- cord-022526-j9kg00qf 4180 13 [ [ -LRB- cord-022526-j9kg00qf 4180 14 204 204 CD cord-022526-j9kg00qf 4180 15 ] ] -RRB- cord-022526-j9kg00qf 4181 1 Systemic systemic JJ cord-022526-j9kg00qf 4181 2 signs sign NNS cord-022526-j9kg00qf 4181 3 may may MD cord-022526-j9kg00qf 4181 4 be be VB cord-022526-j9kg00qf 4181 5 caused cause VBN cord-022526-j9kg00qf 4181 6 by by IN cord-022526-j9kg00qf 4181 7 the the DT cord-022526-j9kg00qf 4181 8 anaphylactic anaphylactic JJ cord-022526-j9kg00qf 4181 9 reaction reaction NN cord-022526-j9kg00qf 4181 10 or or CC cord-022526-j9kg00qf 4181 11 may may MD cord-022526-j9kg00qf 4181 12 be be VB cord-022526-j9kg00qf 4181 13 associated associate VBN cord-022526-j9kg00qf 4181 14 with with IN cord-022526-j9kg00qf 4181 15 systemic systemic JJ cord-022526-j9kg00qf 4181 16 inflammation inflammation NN cord-022526-j9kg00qf 4181 17 triggered trigger VBN cord-022526-j9kg00qf 4181 18 by by IN cord-022526-j9kg00qf 4181 19 microbial microbial JJ cord-022526-j9kg00qf 4181 20 products product NNS cord-022526-j9kg00qf 4181 21 ( ( -LRB- cord-022526-j9kg00qf 4181 22 endotoxin endotoxin NN cord-022526-j9kg00qf 4181 23 ) ) -RRB- cord-022526-j9kg00qf 4181 24 absorbed absorb VBN cord-022526-j9kg00qf 4181 25 through through IN cord-022526-j9kg00qf 4181 26 the the DT cord-022526-j9kg00qf 4181 27 injured injured JJ cord-022526-j9kg00qf 4181 28 and and CC cord-022526-j9kg00qf 4181 29 hyperpermeable hyperpermeable JJ cord-022526-j9kg00qf 4181 30 mucosa mucosa NN cord-022526-j9kg00qf 4181 31 . . . cord-022526-j9kg00qf 4182 1 Intestinal intestinal JJ cord-022526-j9kg00qf 4182 2 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4182 3 in in IN cord-022526-j9kg00qf 4182 4 horses horse NNS cord-022526-j9kg00qf 4182 5 may may MD cord-022526-j9kg00qf 4182 6 be be VB cord-022526-j9kg00qf 4182 7 a a DT cord-022526-j9kg00qf 4182 8 peracute peracute NN cord-022526-j9kg00qf 4182 9 , , , cord-022526-j9kg00qf 4182 10 fulminant fulminant JJ cord-022526-j9kg00qf 4182 11 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4182 12 with with IN cord-022526-j9kg00qf 4182 13 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4182 14 that that WDT cord-022526-j9kg00qf 4182 15 may may MD cord-022526-j9kg00qf 4182 16 be be VB cord-022526-j9kg00qf 4182 17 fatal fatal JJ cord-022526-j9kg00qf 4182 18 . . . cord-022526-j9kg00qf 4183 1 192 192 CD cord-022526-j9kg00qf 4183 2 , , , cord-022526-j9kg00qf 4183 3 205 205 CD cord-022526-j9kg00qf 4184 1 This this DT cord-022526-j9kg00qf 4184 2 form form NN cord-022526-j9kg00qf 4184 3 is be VBZ cord-022526-j9kg00qf 4184 4 characterized characterize VBN cord-022526-j9kg00qf 4184 5 by by IN cord-022526-j9kg00qf 4184 6 severe severe JJ cord-022526-j9kg00qf 4184 7 intramural intramural JJ cord-022526-j9kg00qf 4184 8 edema edema NN cord-022526-j9kg00qf 4184 9 and and CC cord-022526-j9kg00qf 4184 10 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4184 11 inflammation inflammation NN cord-022526-j9kg00qf 4184 12 of of IN cord-022526-j9kg00qf 4184 13 the the DT cord-022526-j9kg00qf 4184 14 large large JJ cord-022526-j9kg00qf 4184 15 intestine intestine NN cord-022526-j9kg00qf 4184 16 , , , cord-022526-j9kg00qf 4184 17 often often RB cord-022526-j9kg00qf 4184 18 producing produce VBG cord-022526-j9kg00qf 4184 19 submucosal submucosal NN cord-022526-j9kg00qf 4184 20 thickening thicken VBG cord-022526-j9kg00qf 4184 21 on on IN cord-022526-j9kg00qf 4184 22 the the DT cord-022526-j9kg00qf 4184 23 order order NN cord-022526-j9kg00qf 4184 24 of of IN cord-022526-j9kg00qf 4184 25 many many JJ cord-022526-j9kg00qf 4184 26 centimeters centimeter NNS cord-022526-j9kg00qf 4184 27 . . . cord-022526-j9kg00qf 4185 1 Vascular vascular JJ cord-022526-j9kg00qf 4185 2 thrombosis thrombosis NN cord-022526-j9kg00qf 4185 3 may may MD cord-022526-j9kg00qf 4185 4 be be VB cord-022526-j9kg00qf 4185 5 widespread widespread JJ cord-022526-j9kg00qf 4185 6 with with IN cord-022526-j9kg00qf 4185 7 mucosal mucosal NN cord-022526-j9kg00qf 4185 8 and and CC cord-022526-j9kg00qf 4185 9 serosal serosal NNP cord-022526-j9kg00qf 4185 10 petechia petechia NNP cord-022526-j9kg00qf 4185 11 and and CC cord-022526-j9kg00qf 4185 12 ecchymoses ecchymoses NNP cord-022526-j9kg00qf 4185 13 . . . cord-022526-j9kg00qf 4186 1 Less less RBR cord-022526-j9kg00qf 4186 2 severe severe JJ cord-022526-j9kg00qf 4186 3 forms form NNS cord-022526-j9kg00qf 4186 4 of of IN cord-022526-j9kg00qf 4186 5 intestinal intestinal JJ cord-022526-j9kg00qf 4186 6 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4186 7 may may MD cord-022526-j9kg00qf 4186 8 manifest manifest VB cord-022526-j9kg00qf 4186 9 as as IN cord-022526-j9kg00qf 4186 10 patchy patchy JJ cord-022526-j9kg00qf 4186 11 areas area NNS cord-022526-j9kg00qf 4186 12 of of IN cord-022526-j9kg00qf 4186 13 intestinal intestinal JJ cord-022526-j9kg00qf 4186 14 edema edema NN cord-022526-j9kg00qf 4186 15 and and CC cord-022526-j9kg00qf 4186 16 congestion congestion NN cord-022526-j9kg00qf 4186 17 . . . cord-022526-j9kg00qf 4187 1 196 196 CD cord-022526-j9kg00qf 4187 2 Diarrhea diarrhea NN cord-022526-j9kg00qf 4187 3 results result NNS cord-022526-j9kg00qf 4187 4 from from IN cord-022526-j9kg00qf 4187 5 intestinal intestinal JJ cord-022526-j9kg00qf 4187 6 inflammation inflammation NN cord-022526-j9kg00qf 4187 7 initiated initiate VBN cord-022526-j9kg00qf 4187 8 by by IN cord-022526-j9kg00qf 4187 9 the the DT cord-022526-j9kg00qf 4187 10 type type NN cord-022526-j9kg00qf 4187 11 I -PRON- PRP cord-022526-j9kg00qf 4187 12 hypersensitivity hypersensitivity VBP cord-022526-j9kg00qf 4187 13 response response NN cord-022526-j9kg00qf 4187 14 . . . cord-022526-j9kg00qf 4188 1 Many many JJ cord-022526-j9kg00qf 4188 2 of of IN cord-022526-j9kg00qf 4188 3 the the DT cord-022526-j9kg00qf 4188 4 mediators mediator NNS cord-022526-j9kg00qf 4188 5 of of IN cord-022526-j9kg00qf 4188 6 type type NN cord-022526-j9kg00qf 4188 7 I -PRON- PRP cord-022526-j9kg00qf 4188 8 hypersensitivity hypersensitivity NN cord-022526-j9kg00qf 4188 9 , , , cord-022526-j9kg00qf 4188 10 such such JJ cord-022526-j9kg00qf 4188 11 as as IN cord-022526-j9kg00qf 4188 12 histamine histamine NN cord-022526-j9kg00qf 4188 13 and and CC cord-022526-j9kg00qf 4188 14 5-hydroxytryptamine 5-hydroxytryptamine CD cord-022526-j9kg00qf 4188 15 , , , cord-022526-j9kg00qf 4188 16 have have VBP cord-022526-j9kg00qf 4188 17 well well RB cord-022526-j9kg00qf 4188 18 - - HYPH cord-022526-j9kg00qf 4188 19 documented document VBN cord-022526-j9kg00qf 4188 20 stimulatory stimulatory JJ cord-022526-j9kg00qf 4188 21 effects effect NNS cord-022526-j9kg00qf 4188 22 on on IN cord-022526-j9kg00qf 4188 23 mucosal mucosal JJ cord-022526-j9kg00qf 4188 24 secretory secretory JJ cord-022526-j9kg00qf 4188 25 activity activity NN cord-022526-j9kg00qf 4188 26 , , , cord-022526-j9kg00qf 4188 27 vascular vascular JJ cord-022526-j9kg00qf 4188 28 and and CC cord-022526-j9kg00qf 4188 29 epithelial epithelial JJ cord-022526-j9kg00qf 4188 30 permeability permeability NN cord-022526-j9kg00qf 4188 31 , , , cord-022526-j9kg00qf 4188 32 and and CC cord-022526-j9kg00qf 4188 33 motility motility NN cord-022526-j9kg00qf 4188 34 [ [ -LRB- cord-022526-j9kg00qf 4188 35 200 200 CD cord-022526-j9kg00qf 4188 36 ] ] -RRB- cord-022526-j9kg00qf 4188 37 [ [ -LRB- cord-022526-j9kg00qf 4188 38 201 201 CD cord-022526-j9kg00qf 4188 39 ] ] -RRB- cord-022526-j9kg00qf 4188 40 [ [ -LRB- cord-022526-j9kg00qf 4188 41 202 202 CD cord-022526-j9kg00qf 4188 42 ] ] -RRB- cord-022526-j9kg00qf 4188 43 in in IN cord-022526-j9kg00qf 4188 44 the the DT cord-022526-j9kg00qf 4188 45 intestine intestine NN cord-022526-j9kg00qf 4188 46 . . . cord-022526-j9kg00qf 4189 1 Systemic systemic JJ cord-022526-j9kg00qf 4189 2 inflammation inflammation NN cord-022526-j9kg00qf 4189 3 from from IN cord-022526-j9kg00qf 4189 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4189 5 may may MD cord-022526-j9kg00qf 4189 6 be be VB cord-022526-j9kg00qf 4189 7 overwhelming overwhelming JJ cord-022526-j9kg00qf 4189 8 once once IN cord-022526-j9kg00qf 4189 9 the the DT cord-022526-j9kg00qf 4189 10 mucosal mucosal JJ cord-022526-j9kg00qf 4189 11 barrier barrier NN cord-022526-j9kg00qf 4189 12 breaks break VBZ cord-022526-j9kg00qf 4189 13 down down RP cord-022526-j9kg00qf 4189 14 . . . cord-022526-j9kg00qf 4190 1 Infarction infarction NN cord-022526-j9kg00qf 4190 2 of of IN cord-022526-j9kg00qf 4190 3 intestinal intestinal JJ cord-022526-j9kg00qf 4190 4 segments segment NNS cord-022526-j9kg00qf 4190 5 and and CC cord-022526-j9kg00qf 4190 6 other other JJ cord-022526-j9kg00qf 4190 7 organs organ NNS cord-022526-j9kg00qf 4190 8 may may MD cord-022526-j9kg00qf 4190 9 occur occur VB cord-022526-j9kg00qf 4190 10 from from IN cord-022526-j9kg00qf 4190 11 intravascular intravascular JJ cord-022526-j9kg00qf 4190 12 coagulation coagulation NN cord-022526-j9kg00qf 4190 13 . . . cord-022526-j9kg00qf 4191 1 Ileus Ileus NNP cord-022526-j9kg00qf 4191 2 , , , cord-022526-j9kg00qf 4191 3 abdominal abdominal JJ cord-022526-j9kg00qf 4191 4 distention distention NN cord-022526-j9kg00qf 4191 5 , , , cord-022526-j9kg00qf 4191 6 and and CC cord-022526-j9kg00qf 4191 7 moderate moderate JJ cord-022526-j9kg00qf 4191 8 to to IN cord-022526-j9kg00qf 4191 9 severe severe JJ cord-022526-j9kg00qf 4191 10 abdominal abdominal JJ cord-022526-j9kg00qf 4191 11 pain pain NN cord-022526-j9kg00qf 4191 12 may may MD cord-022526-j9kg00qf 4191 13 result result VB cord-022526-j9kg00qf 4191 14 from from IN cord-022526-j9kg00qf 4191 15 motility motility NN cord-022526-j9kg00qf 4191 16 disturbances disturbance NNS cord-022526-j9kg00qf 4191 17 and and CC cord-022526-j9kg00qf 4191 18 infarction infarction NN cord-022526-j9kg00qf 4191 19 of of IN cord-022526-j9kg00qf 4191 20 the the DT cord-022526-j9kg00qf 4191 21 large large JJ cord-022526-j9kg00qf 4191 22 intestine intestine NN cord-022526-j9kg00qf 4191 23 . . . cord-022526-j9kg00qf 4192 1 The the DT cord-022526-j9kg00qf 4192 2 clinical clinical JJ cord-022526-j9kg00qf 4192 3 signs sign NNS cord-022526-j9kg00qf 4192 4 are be VBP cord-022526-j9kg00qf 4192 5 similar similar JJ cord-022526-j9kg00qf 4192 6 to to IN cord-022526-j9kg00qf 4192 7 those those DT cord-022526-j9kg00qf 4192 8 described describe VBN cord-022526-j9kg00qf 4192 9 for for IN cord-022526-j9kg00qf 4192 10 other other JJ cord-022526-j9kg00qf 4192 11 forms form NNS cord-022526-j9kg00qf 4192 12 of of IN cord-022526-j9kg00qf 4192 13 peracute peracute NN cord-022526-j9kg00qf 4192 14 colitis colitis NN cord-022526-j9kg00qf 4192 15 . . . cord-022526-j9kg00qf 4193 1 However however RB cord-022526-j9kg00qf 4193 2 , , , cord-022526-j9kg00qf 4193 3 the the DT cord-022526-j9kg00qf 4193 4 severity severity NN cord-022526-j9kg00qf 4193 5 may may MD cord-022526-j9kg00qf 4193 6 vary vary VB cord-022526-j9kg00qf 4193 7 , , , cord-022526-j9kg00qf 4193 8 manifesting manifest VBG cord-022526-j9kg00qf 4193 9 as as IN cord-022526-j9kg00qf 4193 10 colic colic NN cord-022526-j9kg00qf 4193 11 or or CC cord-022526-j9kg00qf 4193 12 moderate moderate JJ cord-022526-j9kg00qf 4193 13 diarrhea diarrhea NN cord-022526-j9kg00qf 4193 14 . . . cord-022526-j9kg00qf 4194 1 Characteristically characteristically RB cord-022526-j9kg00qf 4194 2 , , , cord-022526-j9kg00qf 4194 3 severe severe JJ cord-022526-j9kg00qf 4194 4 shock shock NN cord-022526-j9kg00qf 4194 5 , , , cord-022526-j9kg00qf 4194 6 signs sign NNS cord-022526-j9kg00qf 4194 7 of of IN cord-022526-j9kg00qf 4194 8 systemic systemic JJ cord-022526-j9kg00qf 4194 9 inflammation inflammation NN cord-022526-j9kg00qf 4194 10 from from IN cord-022526-j9kg00qf 4194 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4194 12 , , , cord-022526-j9kg00qf 4194 13 and and CC cord-022526-j9kg00qf 4194 14 severe severe JJ cord-022526-j9kg00qf 4194 15 metabolic metabolic JJ cord-022526-j9kg00qf 4194 16 disturbances disturbance NNS cord-022526-j9kg00qf 4194 17 are be VBP cord-022526-j9kg00qf 4194 18 observable observable JJ cord-022526-j9kg00qf 4194 19 . . . cord-022526-j9kg00qf 4195 1 192 192 CD cord-022526-j9kg00qf 4195 2 , , , cord-022526-j9kg00qf 4195 3 205 205 CD cord-022526-j9kg00qf 4195 4 Heart heart NN cord-022526-j9kg00qf 4195 5 and and CC cord-022526-j9kg00qf 4195 6 respiratory respiratory JJ cord-022526-j9kg00qf 4195 7 rates rate NNS cord-022526-j9kg00qf 4195 8 may may MD cord-022526-j9kg00qf 4195 9 be be VB cord-022526-j9kg00qf 4195 10 elevated elevate VBN cord-022526-j9kg00qf 4195 11 greatly greatly RB cord-022526-j9kg00qf 4195 12 , , , cord-022526-j9kg00qf 4195 13 with with IN cord-022526-j9kg00qf 4195 14 other other JJ cord-022526-j9kg00qf 4195 15 signs sign NNS cord-022526-j9kg00qf 4195 16 of of IN cord-022526-j9kg00qf 4195 17 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 4195 18 collapse collapse NN cord-022526-j9kg00qf 4195 19 such such JJ cord-022526-j9kg00qf 4195 20 as as IN cord-022526-j9kg00qf 4195 21 weak weak JJ cord-022526-j9kg00qf 4195 22 and and CC cord-022526-j9kg00qf 4195 23 thready thready JJ cord-022526-j9kg00qf 4195 24 peripheral peripheral JJ cord-022526-j9kg00qf 4195 25 pulses pulse NNS cord-022526-j9kg00qf 4195 26 and and CC cord-022526-j9kg00qf 4195 27 peripheral peripheral JJ cord-022526-j9kg00qf 4195 28 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 4195 29 . . . cord-022526-j9kg00qf 4196 1 However however RB cord-022526-j9kg00qf 4196 2 , , , cord-022526-j9kg00qf 4196 3 peripheral peripheral JJ cord-022526-j9kg00qf 4196 4 vasodilation vasodilation NN cord-022526-j9kg00qf 4196 5 may may MD cord-022526-j9kg00qf 4196 6 occur occur VB cord-022526-j9kg00qf 4196 7 later later RB cord-022526-j9kg00qf 4196 8 in in IN cord-022526-j9kg00qf 4196 9 the the DT cord-022526-j9kg00qf 4196 10 course course NN cord-022526-j9kg00qf 4196 11 of of IN cord-022526-j9kg00qf 4196 12 disease disease NN cord-022526-j9kg00qf 4196 13 . . . cord-022526-j9kg00qf 4197 1 Dark dark JJ cord-022526-j9kg00qf 4197 2 red red JJ cord-022526-j9kg00qf 4197 3 , , , cord-022526-j9kg00qf 4197 4 muddy muddy JJ cord-022526-j9kg00qf 4197 5 , , , cord-022526-j9kg00qf 4197 6 or or CC cord-022526-j9kg00qf 4197 7 cyanotic cyanotic JJ cord-022526-j9kg00qf 4197 8 mucous mucous JJ cord-022526-j9kg00qf 4197 9 membranes membrane NNS cord-022526-j9kg00qf 4197 10 with with IN cord-022526-j9kg00qf 4197 11 a a DT cord-022526-j9kg00qf 4197 12 prolonged prolonged JJ cord-022526-j9kg00qf 4197 13 capillary capillary JJ cord-022526-j9kg00qf 4197 14 refill refill NN cord-022526-j9kg00qf 4197 15 time time NN cord-022526-j9kg00qf 4197 16 signify signify VB cord-022526-j9kg00qf 4197 17 sepsis sepsis NN cord-022526-j9kg00qf 4197 18 . . . cord-022526-j9kg00qf 4198 1 Borborygmi borborygmus NNS cord-022526-j9kg00qf 4198 2 are be VBP cord-022526-j9kg00qf 4198 3 usually usually RB cord-022526-j9kg00qf 4198 4 absent absent JJ cord-022526-j9kg00qf 4198 5 , , , cord-022526-j9kg00qf 4198 6 and and CC cord-022526-j9kg00qf 4198 7 abdominal abdominal JJ cord-022526-j9kg00qf 4198 8 tympany tympany NN cord-022526-j9kg00qf 4198 9 may may MD cord-022526-j9kg00qf 4198 10 be be VB cord-022526-j9kg00qf 4198 11 heard hear VBN cord-022526-j9kg00qf 4198 12 on on IN cord-022526-j9kg00qf 4198 13 percussion percussion NN cord-022526-j9kg00qf 4198 14 , , , cord-022526-j9kg00qf 4198 15 following follow VBG cord-022526-j9kg00qf 4198 16 ileus ileus NNP cord-022526-j9kg00qf 4198 17 . . . cord-022526-j9kg00qf 4199 1 Moderate moderate JJ cord-022526-j9kg00qf 4199 2 to to IN cord-022526-j9kg00qf 4199 3 severe severe JJ cord-022526-j9kg00qf 4199 4 colic colic NN cord-022526-j9kg00qf 4199 5 may may MD cord-022526-j9kg00qf 4199 6 accompany accompany VB cord-022526-j9kg00qf 4199 7 ileus ileus NNP cord-022526-j9kg00qf 4199 8 . . . cord-022526-j9kg00qf 4200 1 Severe severe JJ cord-022526-j9kg00qf 4200 2 diarrhea diarrhea NN cord-022526-j9kg00qf 4200 3 may may MD cord-022526-j9kg00qf 4200 4 occur occur VB cord-022526-j9kg00qf 4200 5 , , , cord-022526-j9kg00qf 4200 6 but but CC cord-022526-j9kg00qf 4200 7 death death NN cord-022526-j9kg00qf 4200 8 may may MD cord-022526-j9kg00qf 4200 9 occur occur VB cord-022526-j9kg00qf 4200 10 before before IN cord-022526-j9kg00qf 4200 11 diarrhea diarrhea NN cord-022526-j9kg00qf 4200 12 is be VBZ cord-022526-j9kg00qf 4200 13 evident evident JJ cord-022526-j9kg00qf 4200 14 . . . cord-022526-j9kg00qf 4201 1 Multiorgan multiorgan JJ cord-022526-j9kg00qf 4201 2 failure failure NN cord-022526-j9kg00qf 4201 3 from from IN cord-022526-j9kg00qf 4201 4 disseminated disseminate VBN cord-022526-j9kg00qf 4201 5 intravascular intravascular JJ cord-022526-j9kg00qf 4201 6 coagulation coagulation NN cord-022526-j9kg00qf 4201 7 is be VBZ cord-022526-j9kg00qf 4201 8 not not RB cord-022526-j9kg00qf 4201 9 unusual unusual JJ cord-022526-j9kg00qf 4201 10 . . . cord-022526-j9kg00qf 4202 1 Rapid rapid JJ cord-022526-j9kg00qf 4202 2 onset onset NN cord-022526-j9kg00qf 4202 3 of of IN cord-022526-j9kg00qf 4202 4 weakness weakness NN cord-022526-j9kg00qf 4202 5 , , , cord-022526-j9kg00qf 4202 6 staggering staggering JJ cord-022526-j9kg00qf 4202 7 , , , cord-022526-j9kg00qf 4202 8 and and CC cord-022526-j9kg00qf 4202 9 trembling tremble VBG cord-022526-j9kg00qf 4202 10 commonly commonly RB cord-022526-j9kg00qf 4202 11 precedes precede VBZ cord-022526-j9kg00qf 4202 12 death death NN cord-022526-j9kg00qf 4202 13 . . . cord-022526-j9kg00qf 4203 1 The the DT cord-022526-j9kg00qf 4203 2 syndrome syndrome NN cord-022526-j9kg00qf 4203 3 may may MD cord-022526-j9kg00qf 4203 4 cause cause VB cord-022526-j9kg00qf 4203 5 death death NN cord-022526-j9kg00qf 4203 6 in in IN cord-022526-j9kg00qf 4203 7 4 4 CD cord-022526-j9kg00qf 4203 8 to to TO cord-022526-j9kg00qf 4203 9 24 24 CD cord-022526-j9kg00qf 4203 10 hours hour NNS cord-022526-j9kg00qf 4203 11 . . . cord-022526-j9kg00qf 4204 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 4204 2 abnormalities abnormality NNS cord-022526-j9kg00qf 4204 3 include include VBP cord-022526-j9kg00qf 4204 4 severe severe JJ cord-022526-j9kg00qf 4204 5 neutropenia neutropenia NN cord-022526-j9kg00qf 4204 6 and and CC cord-022526-j9kg00qf 4204 7 leukopenia leukopenia NN cord-022526-j9kg00qf 4204 8 , , , cord-022526-j9kg00qf 4204 9 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 4204 10 , , , cord-022526-j9kg00qf 4204 11 and and CC cord-022526-j9kg00qf 4204 12 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 4204 13 . . . cord-022526-j9kg00qf 4205 1 192 192 CD cord-022526-j9kg00qf 4205 2 Serum serum NN cord-022526-j9kg00qf 4205 3 biochemical biochemical JJ cord-022526-j9kg00qf 4205 4 alterations alteration NNS cord-022526-j9kg00qf 4205 5 include include VBP cord-022526-j9kg00qf 4205 6 hyponatremia hyponatremia NN cord-022526-j9kg00qf 4205 7 , , , cord-022526-j9kg00qf 4205 8 hypokalemia hypokalemia NN cord-022526-j9kg00qf 4205 9 , , , cord-022526-j9kg00qf 4205 10 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4205 11 , , , cord-022526-j9kg00qf 4205 12 and and CC cord-022526-j9kg00qf 4205 13 severe severe JJ cord-022526-j9kg00qf 4205 14 metabolic metabolic JJ cord-022526-j9kg00qf 4205 15 acidosis acidosis NN cord-022526-j9kg00qf 4205 16 . . . cord-022526-j9kg00qf 4206 1 Blood blood NN cord-022526-j9kg00qf 4206 2 urea urea NN cord-022526-j9kg00qf 4206 3 nitrogen nitrogen NN cord-022526-j9kg00qf 4206 4 and and CC cord-022526-j9kg00qf 4206 5 creatinine creatinine NN cord-022526-j9kg00qf 4206 6 may may MD cord-022526-j9kg00qf 4206 7 be be VB cord-022526-j9kg00qf 4206 8 elevated elevate VBN cord-022526-j9kg00qf 4206 9 from from IN cord-022526-j9kg00qf 4206 10 prerenal prerenal JJ cord-022526-j9kg00qf 4206 11 or or CC cord-022526-j9kg00qf 4206 12 renal renal JJ cord-022526-j9kg00qf 4206 13 azotemia azotemia NN cord-022526-j9kg00qf 4206 14 . . . cord-022526-j9kg00qf 4207 1 If if IN cord-022526-j9kg00qf 4207 2 acute acute JJ cord-022526-j9kg00qf 4207 3 renal renal JJ cord-022526-j9kg00qf 4207 4 failure failure NN cord-022526-j9kg00qf 4207 5 accompanies accompany VBZ cord-022526-j9kg00qf 4207 6 the the DT cord-022526-j9kg00qf 4207 7 colitis colitis NN cord-022526-j9kg00qf 4207 8 , , , cord-022526-j9kg00qf 4207 9 hyperkalemia hyperkalemia NN cord-022526-j9kg00qf 4207 10 may may MD cord-022526-j9kg00qf 4207 11 result result VB cord-022526-j9kg00qf 4207 12 . . . cord-022526-j9kg00qf 4208 1 Hepatocellular hepatocellular JJ cord-022526-j9kg00qf 4208 2 enzyme enzyme NN cord-022526-j9kg00qf 4208 3 activity activity NN cord-022526-j9kg00qf 4208 4 may may MD cord-022526-j9kg00qf 4208 5 be be VB cord-022526-j9kg00qf 4208 6 elevated elevate VBN cord-022526-j9kg00qf 4208 7 in in IN cord-022526-j9kg00qf 4208 8 the the DT cord-022526-j9kg00qf 4208 9 serum serum NN cord-022526-j9kg00qf 4208 10 from from IN cord-022526-j9kg00qf 4208 11 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4208 12 . . . cord-022526-j9kg00qf 4209 1 Severe severe JJ cord-022526-j9kg00qf 4209 2 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 4209 3 are be VBP cord-022526-j9kg00qf 4209 4 common common JJ cord-022526-j9kg00qf 4209 5 , , , cord-022526-j9kg00qf 4209 6 resulting result VBG cord-022526-j9kg00qf 4209 7 in in IN cord-022526-j9kg00qf 4209 8 prolonged prolonged JJ cord-022526-j9kg00qf 4209 9 coagulation coagulation NN cord-022526-j9kg00qf 4209 10 times time NNS cord-022526-j9kg00qf 4209 11 , , , cord-022526-j9kg00qf 4209 12 elevated elevated JJ cord-022526-j9kg00qf 4209 13 fibrinogen fibrinogen NN cord-022526-j9kg00qf 4209 14 , , , cord-022526-j9kg00qf 4209 15 decreased decrease VBD cord-022526-j9kg00qf 4209 16 antithrombin antithrombin NN cord-022526-j9kg00qf 4209 17 III iii CD cord-022526-j9kg00qf 4209 18 activity activity NN cord-022526-j9kg00qf 4209 19 , , , cord-022526-j9kg00qf 4209 20 and and CC cord-022526-j9kg00qf 4209 21 elevated elevated JJ cord-022526-j9kg00qf 4209 22 plasma plasma NN cord-022526-j9kg00qf 4209 23 concentration concentration NN cord-022526-j9kg00qf 4209 24 of of IN cord-022526-j9kg00qf 4209 25 fibrin fibrin NN cord-022526-j9kg00qf 4209 26 degradation degradation NN cord-022526-j9kg00qf 4209 27 products product NNS cord-022526-j9kg00qf 4209 28 . . . cord-022526-j9kg00qf 4210 1 Analysis analysis NN cord-022526-j9kg00qf 4210 2 of of IN cord-022526-j9kg00qf 4210 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 4210 4 fluid fluid NN cord-022526-j9kg00qf 4210 5 may may MD cord-022526-j9kg00qf 4210 6 be be VB cord-022526-j9kg00qf 4210 7 valuable valuable JJ cord-022526-j9kg00qf 4210 8 because because IN cord-022526-j9kg00qf 4210 9 infarction infarction NN cord-022526-j9kg00qf 4210 10 of of IN cord-022526-j9kg00qf 4210 11 the the DT cord-022526-j9kg00qf 4210 12 large large JJ cord-022526-j9kg00qf 4210 13 intestine intestine NN cord-022526-j9kg00qf 4210 14 is be VBZ cord-022526-j9kg00qf 4210 15 not not RB cord-022526-j9kg00qf 4210 16 unusual unusual JJ cord-022526-j9kg00qf 4210 17 . . . cord-022526-j9kg00qf 4211 1 Protein protein NN cord-022526-j9kg00qf 4211 2 concentration concentration NN cord-022526-j9kg00qf 4211 3 and and CC cord-022526-j9kg00qf 4211 4 the the DT cord-022526-j9kg00qf 4211 5 white white JJ cord-022526-j9kg00qf 4211 6 blood blood NN cord-022526-j9kg00qf 4211 7 cell cell NN cord-022526-j9kg00qf 4211 8 count count NN cord-022526-j9kg00qf 4211 9 may may MD cord-022526-j9kg00qf 4211 10 be be VB cord-022526-j9kg00qf 4211 11 elevated elevate VBN cord-022526-j9kg00qf 4211 12 . . . cord-022526-j9kg00qf 4212 1 Red red JJ cord-022526-j9kg00qf 4212 2 blood blood NN cord-022526-j9kg00qf 4212 3 cell cell NN cord-022526-j9kg00qf 4212 4 counts count NNS cord-022526-j9kg00qf 4212 5 are be VBP cord-022526-j9kg00qf 4212 6 less less RBR cord-022526-j9kg00qf 4212 7 likely likely JJ cord-022526-j9kg00qf 4212 8 to to TO cord-022526-j9kg00qf 4212 9 be be VB cord-022526-j9kg00qf 4212 10 elevated elevate VBN cord-022526-j9kg00qf 4212 11 , , , cord-022526-j9kg00qf 4212 12 because because IN cord-022526-j9kg00qf 4212 13 infarction infarction NN cord-022526-j9kg00qf 4212 14 and and CC cord-022526-j9kg00qf 4212 15 not not RB cord-022526-j9kg00qf 4212 16 strangulation strangulation NN cord-022526-j9kg00qf 4212 17 of of IN cord-022526-j9kg00qf 4212 18 the the DT cord-022526-j9kg00qf 4212 19 intestine intestine NN cord-022526-j9kg00qf 4212 20 occurs occur VBZ cord-022526-j9kg00qf 4212 21 . . . cord-022526-j9kg00qf 4213 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 4213 2 is be VBZ cord-022526-j9kg00qf 4213 3 based base VBN cord-022526-j9kg00qf 4213 4 on on IN cord-022526-j9kg00qf 4213 5 clinical clinical JJ cord-022526-j9kg00qf 4213 6 signs sign NNS cord-022526-j9kg00qf 4213 7 , , , cord-022526-j9kg00qf 4213 8 postmortem postmortem JJ cord-022526-j9kg00qf 4213 9 findings finding NNS cord-022526-j9kg00qf 4213 10 , , , cord-022526-j9kg00qf 4213 11 and and CC cord-022526-j9kg00qf 4213 12 exclusion exclusion NN cord-022526-j9kg00qf 4213 13 of of IN cord-022526-j9kg00qf 4213 14 other other JJ cord-022526-j9kg00qf 4213 15 causes cause NNS cord-022526-j9kg00qf 4213 16 . . . cord-022526-j9kg00qf 4214 1 Cultures culture NNS cord-022526-j9kg00qf 4214 2 and and CC cord-022526-j9kg00qf 4214 3 toxicologic toxicologic NN cord-022526-j9kg00qf 4214 4 analysis analysis NN cord-022526-j9kg00qf 4214 5 of of IN cord-022526-j9kg00qf 4214 6 fecal fecal JJ cord-022526-j9kg00qf 4214 7 samples sample NNS cord-022526-j9kg00qf 4214 8 and and CC cord-022526-j9kg00qf 4214 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4214 10 tissues tissue NNS cord-022526-j9kg00qf 4214 11 fail fail VBP cord-022526-j9kg00qf 4214 12 to to TO cord-022526-j9kg00qf 4214 13 demonstrate demonstrate VB cord-022526-j9kg00qf 4214 14 a a DT cord-022526-j9kg00qf 4214 15 clear clear JJ cord-022526-j9kg00qf 4214 16 cause cause NN cord-022526-j9kg00qf 4214 17 . . . cord-022526-j9kg00qf 4215 1 Other other JJ cord-022526-j9kg00qf 4215 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 4215 3 tests test NNS cord-022526-j9kg00qf 4215 4 are be VBP cord-022526-j9kg00qf 4215 5 also also RB cord-022526-j9kg00qf 4215 6 inconclusive inconclusive JJ cord-022526-j9kg00qf 4215 7 . . . cord-022526-j9kg00qf 4216 1 If if IN cord-022526-j9kg00qf 4216 2 an an DT cord-022526-j9kg00qf 4216 3 antigen antigen NN cord-022526-j9kg00qf 4216 4 is be VBZ cord-022526-j9kg00qf 4216 5 suspected suspect VBN cord-022526-j9kg00qf 4216 6 as as IN cord-022526-j9kg00qf 4216 7 the the DT cord-022526-j9kg00qf 4216 8 trigger trigger NN cord-022526-j9kg00qf 4216 9 of of IN cord-022526-j9kg00qf 4216 10 the the DT cord-022526-j9kg00qf 4216 11 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4216 12 , , , cord-022526-j9kg00qf 4216 13 a a DT cord-022526-j9kg00qf 4216 14 Prausnitz Prausnitz NNP cord-022526-j9kg00qf 4216 15 - - HYPH cord-022526-j9kg00qf 4216 16 Küstner Küstner NNP cord-022526-j9kg00qf 4216 17 passive passive JJ cord-022526-j9kg00qf 4216 18 cutaneous cutaneous JJ cord-022526-j9kg00qf 4216 19 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4216 20 sensitization sensitization NN cord-022526-j9kg00qf 4216 21 test test NN cord-022526-j9kg00qf 4216 22 can can MD cord-022526-j9kg00qf 4216 23 confirm confirm VB cord-022526-j9kg00qf 4216 24 the the DT cord-022526-j9kg00qf 4216 25 presence presence NN cord-022526-j9kg00qf 4216 26 of of IN cord-022526-j9kg00qf 4216 27 antigen antigen NN cord-022526-j9kg00qf 4216 28 - - HYPH cord-022526-j9kg00qf 4216 29 specific specific JJ cord-022526-j9kg00qf 4216 30 IgE ige NN cord-022526-j9kg00qf 4216 31 in in IN cord-022526-j9kg00qf 4216 32 the the DT cord-022526-j9kg00qf 4216 33 patient patient JJ cord-022526-j9kg00qf 4216 34 serum serum NN cord-022526-j9kg00qf 4216 35 . . . cord-022526-j9kg00qf 4217 1 196 196 CD cord-022526-j9kg00qf 4218 1 Overeating overeat VBG cord-022526-j9kg00qf 4218 2 of of IN cord-022526-j9kg00qf 4218 3 soluble soluble JJ cord-022526-j9kg00qf 4218 4 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4218 5 , , , cord-022526-j9kg00qf 4218 6 especially especially RB cord-022526-j9kg00qf 4218 7 so so RB cord-022526-j9kg00qf 4218 8 - - HYPH cord-022526-j9kg00qf 4218 9 called call VBN cord-022526-j9kg00qf 4218 10 hot hot JJ cord-022526-j9kg00qf 4218 11 grains grain NNS cord-022526-j9kg00qf 4218 12 such such JJ cord-022526-j9kg00qf 4218 13 as as IN cord-022526-j9kg00qf 4218 14 corn corn NN cord-022526-j9kg00qf 4218 15 , , , cord-022526-j9kg00qf 4218 16 overwhelms overwhelm VBZ cord-022526-j9kg00qf 4218 17 the the DT cord-022526-j9kg00qf 4218 18 digestive digestive JJ cord-022526-j9kg00qf 4218 19 capability capability NN cord-022526-j9kg00qf 4218 20 of of IN cord-022526-j9kg00qf 4218 21 the the DT cord-022526-j9kg00qf 4218 22 small small JJ cord-022526-j9kg00qf 4218 23 intestine intestine NN cord-022526-j9kg00qf 4218 24 , , , cord-022526-j9kg00qf 4218 25 resulting result VBG cord-022526-j9kg00qf 4218 26 in in IN cord-022526-j9kg00qf 4218 27 a a DT cord-022526-j9kg00qf 4218 28 high high JJ cord-022526-j9kg00qf 4218 29 percentage percentage NN cord-022526-j9kg00qf 4218 30 of of IN cord-022526-j9kg00qf 4218 31 the the DT cord-022526-j9kg00qf 4218 32 soluble soluble JJ cord-022526-j9kg00qf 4218 33 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4218 34 entering enter VBG cord-022526-j9kg00qf 4218 35 the the DT cord-022526-j9kg00qf 4218 36 large large JJ cord-022526-j9kg00qf 4218 37 intestine intestine NN cord-022526-j9kg00qf 4218 38 . . . cord-022526-j9kg00qf 4219 1 The the DT cord-022526-j9kg00qf 4219 2 amount amount NN cord-022526-j9kg00qf 4219 3 of of IN cord-022526-j9kg00qf 4219 4 soluble soluble JJ cord-022526-j9kg00qf 4219 5 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4219 6 that that WDT cord-022526-j9kg00qf 4219 7 produce produce VBP cord-022526-j9kg00qf 4219 8 diarrhea diarrhea NN cord-022526-j9kg00qf 4219 9 varies vary VBZ cord-022526-j9kg00qf 4219 10 according accord VBG cord-022526-j9kg00qf 4219 11 to to IN cord-022526-j9kg00qf 4219 12 the the DT cord-022526-j9kg00qf 4219 13 previous previous JJ cord-022526-j9kg00qf 4219 14 dietary dietary JJ cord-022526-j9kg00qf 4219 15 history history NN cord-022526-j9kg00qf 4219 16 of of IN cord-022526-j9kg00qf 4219 17 the the DT cord-022526-j9kg00qf 4219 18 individual individual NN cord-022526-j9kg00qf 4219 19 . . . cord-022526-j9kg00qf 4220 1 Horses horse NNS cord-022526-j9kg00qf 4220 2 fed feed VBD cord-022526-j9kg00qf 4220 3 diets diet NNS cord-022526-j9kg00qf 4220 4 higher higher RBR cord-022526-j9kg00qf 4220 5 in in IN cord-022526-j9kg00qf 4220 6 soluble soluble JJ cord-022526-j9kg00qf 4220 7 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4220 8 are be VBP cord-022526-j9kg00qf 4220 9 more more RBR cord-022526-j9kg00qf 4220 10 resistant resistant JJ cord-022526-j9kg00qf 4220 11 to to IN cord-022526-j9kg00qf 4220 12 the the DT cord-022526-j9kg00qf 4220 13 deleterious deleterious JJ cord-022526-j9kg00qf 4220 14 effects effect NNS cord-022526-j9kg00qf 4220 15 of of IN cord-022526-j9kg00qf 4220 16 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4220 17 overload overload NN cord-022526-j9kg00qf 4220 18 . . . cord-022526-j9kg00qf 4221 1 Gradual gradual JJ cord-022526-j9kg00qf 4221 2 accommodation accommodation NN cord-022526-j9kg00qf 4221 3 to to IN cord-022526-j9kg00qf 4221 4 a a DT cord-022526-j9kg00qf 4221 5 diet diet NN cord-022526-j9kg00qf 4221 6 high high RB cord-022526-j9kg00qf 4221 7 in in IN cord-022526-j9kg00qf 4221 8 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4221 9 can can MD cord-022526-j9kg00qf 4221 10 be be VB cord-022526-j9kg00qf 4221 11 accomplished accomplish VBN cord-022526-j9kg00qf 4221 12 over over IN cord-022526-j9kg00qf 4221 13 several several JJ cord-022526-j9kg00qf 4221 14 weeks week NNS cord-022526-j9kg00qf 4221 15 . . . cord-022526-j9kg00qf 4222 1 However however RB cord-022526-j9kg00qf 4222 2 , , , cord-022526-j9kg00qf 4222 3 horses horse NNS cord-022526-j9kg00qf 4222 4 fed feed VBD cord-022526-j9kg00qf 4222 5 an an DT cord-022526-j9kg00qf 4222 6 unusually unusually RB cord-022526-j9kg00qf 4222 7 large large JJ cord-022526-j9kg00qf 4222 8 amount amount NN cord-022526-j9kg00qf 4222 9 of of IN cord-022526-j9kg00qf 4222 10 grains grain NNS cord-022526-j9kg00qf 4222 11 or or CC cord-022526-j9kg00qf 4222 12 other other JJ cord-022526-j9kg00qf 4222 13 form form NN cord-022526-j9kg00qf 4222 14 of of IN cord-022526-j9kg00qf 4222 15 soluble soluble JJ cord-022526-j9kg00qf 4222 16 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4222 17 often often RB cord-022526-j9kg00qf 4222 18 develop develop VBP cord-022526-j9kg00qf 4222 19 diarrhea diarrhea NN cord-022526-j9kg00qf 4222 20 and and CC cord-022526-j9kg00qf 4222 21 may may MD cord-022526-j9kg00qf 4222 22 , , , cord-022526-j9kg00qf 4222 23 depending depend VBG cord-022526-j9kg00qf 4222 24 on on IN cord-022526-j9kg00qf 4222 25 the the DT cord-022526-j9kg00qf 4222 26 amount amount NN cord-022526-j9kg00qf 4222 27 ingested ingest VBN cord-022526-j9kg00qf 4222 28 , , , cord-022526-j9kg00qf 4222 29 develop develop VB cord-022526-j9kg00qf 4222 30 severe severe JJ cord-022526-j9kg00qf 4222 31 colitis colitis NN cord-022526-j9kg00qf 4222 32 , , , cord-022526-j9kg00qf 4222 33 systemic systemic JJ cord-022526-j9kg00qf 4222 34 inflammation inflammation NN cord-022526-j9kg00qf 4222 35 from from IN cord-022526-j9kg00qf 4222 36 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4222 37 , , , cord-022526-j9kg00qf 4222 38 metabolic metabolic JJ cord-022526-j9kg00qf 4222 39 acidosis acidosis NN cord-022526-j9kg00qf 4222 40 , , , cord-022526-j9kg00qf 4222 41 and and CC cord-022526-j9kg00qf 4222 42 laminitis laminitis NN cord-022526-j9kg00qf 4222 43 . . . cord-022526-j9kg00qf 4223 1 [ [ -LRB- cord-022526-j9kg00qf 4223 2 206 206 CD cord-022526-j9kg00qf 4223 3 ] ] -RRB- cord-022526-j9kg00qf 4223 4 [ [ -LRB- cord-022526-j9kg00qf 4223 5 207 207 CD cord-022526-j9kg00qf 4223 6 ] ] -RRB- cord-022526-j9kg00qf 4223 7 [ [ -LRB- cord-022526-j9kg00qf 4223 8 208 208 CD cord-022526-j9kg00qf 4223 9 ] ] -RRB- cord-022526-j9kg00qf 4223 10 [ [ -LRB- cord-022526-j9kg00qf 4223 11 209 209 CD cord-022526-j9kg00qf 4223 12 ] ] -RRB- cord-022526-j9kg00qf 4224 1 The the DT cord-022526-j9kg00qf 4224 2 pathogenesis pathogenesis NN cord-022526-j9kg00qf 4224 3 of of IN cord-022526-j9kg00qf 4224 4 colitis colitis NN cord-022526-j9kg00qf 4224 5 from from IN cord-022526-j9kg00qf 4224 6 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4224 7 overload overload NN cord-022526-j9kg00qf 4224 8 is be VBZ cord-022526-j9kg00qf 4224 9 caused cause VBN cord-022526-j9kg00qf 4224 10 primarily primarily RB cord-022526-j9kg00qf 4224 11 by by IN cord-022526-j9kg00qf 4224 12 the the DT cord-022526-j9kg00qf 4224 13 toxic toxic JJ cord-022526-j9kg00qf 4224 14 effects effect NNS cord-022526-j9kg00qf 4224 15 on on IN cord-022526-j9kg00qf 4224 16 the the DT cord-022526-j9kg00qf 4224 17 microbial microbial JJ cord-022526-j9kg00qf 4224 18 flora flora NNS cord-022526-j9kg00qf 4224 19 in in IN cord-022526-j9kg00qf 4224 20 the the DT cord-022526-j9kg00qf 4224 21 large large JJ cord-022526-j9kg00qf 4224 22 intestine intestine NN cord-022526-j9kg00qf 4224 23 . . . cord-022526-j9kg00qf 4225 1 207 207 CD cord-022526-j9kg00qf 4226 1 A a DT cord-022526-j9kg00qf 4226 2 sudden sudden JJ cord-022526-j9kg00qf 4226 3 delivery delivery NN cord-022526-j9kg00qf 4226 4 of of IN cord-022526-j9kg00qf 4226 5 soluble soluble JJ cord-022526-j9kg00qf 4226 6 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4226 7 to to IN cord-022526-j9kg00qf 4226 8 the the DT cord-022526-j9kg00qf 4226 9 large large JJ cord-022526-j9kg00qf 4226 10 intestine intestine NN cord-022526-j9kg00qf 4226 11 causes cause VBZ cord-022526-j9kg00qf 4226 12 rapid rapid JJ cord-022526-j9kg00qf 4226 13 fermentation fermentation NN cord-022526-j9kg00qf 4226 14 by by IN cord-022526-j9kg00qf 4226 15 gram gram NN cord-022526-j9kg00qf 4226 16 - - HYPH cord-022526-j9kg00qf 4226 17 positive positive JJ cord-022526-j9kg00qf 4226 18 lactic lactic JJ cord-022526-j9kg00qf 4226 19 acid acid NN cord-022526-j9kg00qf 4226 20 - - HYPH cord-022526-j9kg00qf 4226 21 producing produce VBG cord-022526-j9kg00qf 4226 22 bacteria bacteria NNS cord-022526-j9kg00qf 4226 23 and and CC cord-022526-j9kg00qf 4226 24 a a DT cord-022526-j9kg00qf 4226 25 sudden sudden JJ cord-022526-j9kg00qf 4226 26 increase increase NN cord-022526-j9kg00qf 4226 27 in in IN cord-022526-j9kg00qf 4226 28 organic organic JJ cord-022526-j9kg00qf 4226 29 acid acid NN cord-022526-j9kg00qf 4226 30 production production NN cord-022526-j9kg00qf 4226 31 . . . cord-022526-j9kg00qf 4227 1 The the DT cord-022526-j9kg00qf 4227 2 cecal cecal JJ cord-022526-j9kg00qf 4227 3 pH ph NN cord-022526-j9kg00qf 4227 4 rapidly rapidly RB cord-022526-j9kg00qf 4227 5 decreases decrease VBZ cord-022526-j9kg00qf 4227 6 , , , cord-022526-j9kg00qf 4227 7 and and CC cord-022526-j9kg00qf 4227 8 the the DT cord-022526-j9kg00qf 4227 9 lactic lactic JJ cord-022526-j9kg00qf 4227 10 acid acid NN cord-022526-j9kg00qf 4227 11 concentration concentration NN cord-022526-j9kg00qf 4227 12 rapidly rapidly RB cord-022526-j9kg00qf 4227 13 increases increase VBZ cord-022526-j9kg00qf 4227 14 . . . cord-022526-j9kg00qf 4228 1 Rapid rapid JJ cord-022526-j9kg00qf 4228 2 organic organic JJ cord-022526-j9kg00qf 4228 3 acid acid NN cord-022526-j9kg00qf 4228 4 production production NN cord-022526-j9kg00qf 4228 5 overwhelms overwhelm VBZ cord-022526-j9kg00qf 4228 6 the the DT cord-022526-j9kg00qf 4228 7 buffering buffering NN cord-022526-j9kg00qf 4228 8 capacity capacity NN cord-022526-j9kg00qf 4228 9 of of IN cord-022526-j9kg00qf 4228 10 the the DT cord-022526-j9kg00qf 4228 11 large large JJ cord-022526-j9kg00qf 4228 12 intestine intestine NN cord-022526-j9kg00qf 4228 13 not not RB cord-022526-j9kg00qf 4228 14 only only RB cord-022526-j9kg00qf 4228 15 by by IN cord-022526-j9kg00qf 4228 16 directly directly RB cord-022526-j9kg00qf 4228 17 depleting deplete VBG cord-022526-j9kg00qf 4228 18 the the DT cord-022526-j9kg00qf 4228 19 buffers buffer NNS cord-022526-j9kg00qf 4228 20 found find VBN cord-022526-j9kg00qf 4228 21 in in IN cord-022526-j9kg00qf 4228 22 the the DT cord-022526-j9kg00qf 4228 23 contents content NNS cord-022526-j9kg00qf 4228 24 but but CC cord-022526-j9kg00qf 4228 25 also also RB cord-022526-j9kg00qf 4228 26 by by IN cord-022526-j9kg00qf 4228 27 reducing reduce VBG cord-022526-j9kg00qf 4228 28 the the DT cord-022526-j9kg00qf 4228 29 efficiency efficiency NN cord-022526-j9kg00qf 4228 30 of of IN cord-022526-j9kg00qf 4228 31 buffer buffer NN cord-022526-j9kg00qf 4228 32 secretion secretion NN cord-022526-j9kg00qf 4228 33 . . . cord-022526-j9kg00qf 4229 1 Bicarbonate bicarbonate NN cord-022526-j9kg00qf 4229 2 secretion secretion NN cord-022526-j9kg00qf 4229 3 is be VBZ cord-022526-j9kg00qf 4229 4 linked link VBN cord-022526-j9kg00qf 4229 5 to to IN cord-022526-j9kg00qf 4229 6 absorption absorption NN cord-022526-j9kg00qf 4229 7 of of IN cord-022526-j9kg00qf 4229 8 volatile volatile JJ cord-022526-j9kg00qf 4229 9 fatty fatty JJ cord-022526-j9kg00qf 4229 10 acids acid NNS cord-022526-j9kg00qf 4229 11 , , , cord-022526-j9kg00qf 4229 12 which which WDT cord-022526-j9kg00qf 4229 13 are be VBP cord-022526-j9kg00qf 4229 14 produced produce VBN cord-022526-j9kg00qf 4229 15 in in IN cord-022526-j9kg00qf 4229 16 low low JJ cord-022526-j9kg00qf 4229 17 amounts amount NNS cord-022526-j9kg00qf 4229 18 by by IN cord-022526-j9kg00qf 4229 19 fermentation fermentation NN cord-022526-j9kg00qf 4229 20 of of IN cord-022526-j9kg00qf 4229 21 soluble soluble JJ cord-022526-j9kg00qf 4229 22 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4229 23 . . . cord-022526-j9kg00qf 4230 1 The the DT cord-022526-j9kg00qf 4230 2 contents content NNS cord-022526-j9kg00qf 4230 3 of of IN cord-022526-j9kg00qf 4230 4 the the DT cord-022526-j9kg00qf 4230 5 large large JJ cord-022526-j9kg00qf 4230 6 intestine intestine NN cord-022526-j9kg00qf 4230 7 become become VBP cord-022526-j9kg00qf 4230 8 profoundly profoundly RB cord-022526-j9kg00qf 4230 9 acidic acidic JJ cord-022526-j9kg00qf 4230 10 , , , cord-022526-j9kg00qf 4230 11 resulting result VBG cord-022526-j9kg00qf 4230 12 in in IN cord-022526-j9kg00qf 4230 13 unfavorable unfavorable JJ cord-022526-j9kg00qf 4230 14 conditions condition NNS cord-022526-j9kg00qf 4230 15 for for IN cord-022526-j9kg00qf 4230 16 the the DT cord-022526-j9kg00qf 4230 17 microbial microbial JJ cord-022526-j9kg00qf 4230 18 flora flora NNS cord-022526-j9kg00qf 4230 19 . . . cord-022526-j9kg00qf 4231 1 Lactic lactic JJ cord-022526-j9kg00qf 4231 2 acid acid NN cord-022526-j9kg00qf 4231 3 - - HYPH cord-022526-j9kg00qf 4231 4 producing produce VBG cord-022526-j9kg00qf 4231 5 bacteria bacteria NNS cord-022526-j9kg00qf 4231 6 flourish flourish VBP cord-022526-j9kg00qf 4231 7 , , , cord-022526-j9kg00qf 4231 8 while while IN cord-022526-j9kg00qf 4231 9 the the DT cord-022526-j9kg00qf 4231 10 gram gram NN cord-022526-j9kg00qf 4231 11 - - HYPH cord-022526-j9kg00qf 4231 12 negative negative JJ cord-022526-j9kg00qf 4231 13 bacteria bacteria NNS cord-022526-j9kg00qf 4231 14 , , , cord-022526-j9kg00qf 4231 15 especially especially RB cord-022526-j9kg00qf 4231 16 the the DT cord-022526-j9kg00qf 4231 17 Enterobacteriaceae Enterobacteriaceae NNP cord-022526-j9kg00qf 4231 18 , , , cord-022526-j9kg00qf 4231 19 are be VBP cord-022526-j9kg00qf 4231 20 killed kill VBN cord-022526-j9kg00qf 4231 21 in in IN cord-022526-j9kg00qf 4231 22 large large JJ cord-022526-j9kg00qf 4231 23 numbers number NNS cord-022526-j9kg00qf 4231 24 by by IN cord-022526-j9kg00qf 4231 25 the the DT cord-022526-j9kg00qf 4231 26 acids acid NNS cord-022526-j9kg00qf 4231 27 . . . cord-022526-j9kg00qf 4232 1 Large large JJ cord-022526-j9kg00qf 4232 2 quantities quantity NNS cord-022526-j9kg00qf 4232 3 of of IN cord-022526-j9kg00qf 4232 4 endotoxin endotoxin NN cord-022526-j9kg00qf 4232 5 are be VBP cord-022526-j9kg00qf 4232 6 released release VBN cord-022526-j9kg00qf 4232 7 from from IN cord-022526-j9kg00qf 4232 8 the the DT cord-022526-j9kg00qf 4232 9 dying die VBG cord-022526-j9kg00qf 4232 10 bacteria bacteria NNS cord-022526-j9kg00qf 4232 11 . . . cord-022526-j9kg00qf 4233 1 208 208 CD cord-022526-j9kg00qf 4234 1 The the DT cord-022526-j9kg00qf 4234 2 osmotic osmotic JJ cord-022526-j9kg00qf 4234 3 load load NN cord-022526-j9kg00qf 4234 4 from from IN cord-022526-j9kg00qf 4234 5 the the DT cord-022526-j9kg00qf 4234 6 lactic lactic JJ cord-022526-j9kg00qf 4234 7 acid acid NN cord-022526-j9kg00qf 4234 8 produced produce VBN cord-022526-j9kg00qf 4234 9 in in IN cord-022526-j9kg00qf 4234 10 the the DT cord-022526-j9kg00qf 4234 11 large large JJ cord-022526-j9kg00qf 4234 12 intestine intestine NN cord-022526-j9kg00qf 4234 13 is be VBZ cord-022526-j9kg00qf 4234 14 an an DT cord-022526-j9kg00qf 4234 15 important important JJ cord-022526-j9kg00qf 4234 16 factor factor NN cord-022526-j9kg00qf 4234 17 in in IN cord-022526-j9kg00qf 4234 18 the the DT cord-022526-j9kg00qf 4234 19 development development NN cord-022526-j9kg00qf 4234 20 of of IN cord-022526-j9kg00qf 4234 21 diarrhea diarrhea NN cord-022526-j9kg00qf 4234 22 because because IN cord-022526-j9kg00qf 4234 23 organic organic JJ cord-022526-j9kg00qf 4234 24 acids acid NNS cord-022526-j9kg00qf 4234 25 such such JJ cord-022526-j9kg00qf 4234 26 as as IN cord-022526-j9kg00qf 4234 27 lactic lactic JJ cord-022526-j9kg00qf 4234 28 acid acid NN cord-022526-j9kg00qf 4234 29 are be VBP cord-022526-j9kg00qf 4234 30 absorbed absorb VBN cord-022526-j9kg00qf 4234 31 poorly poorly RB cord-022526-j9kg00qf 4234 32 . . . cord-022526-j9kg00qf 4235 1 Mild mild JJ cord-022526-j9kg00qf 4235 2 cases case NNS cord-022526-j9kg00qf 4235 3 of of IN cord-022526-j9kg00qf 4235 4 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4235 5 overload overload NN cord-022526-j9kg00qf 4235 6 may may MD cord-022526-j9kg00qf 4235 7 result result VB cord-022526-j9kg00qf 4235 8 purely purely RB cord-022526-j9kg00qf 4235 9 from from IN cord-022526-j9kg00qf 4235 10 osmotic osmotic JJ cord-022526-j9kg00qf 4235 11 diarrhea diarrhea NN cord-022526-j9kg00qf 4235 12 . . . cord-022526-j9kg00qf 4236 1 In in IN cord-022526-j9kg00qf 4236 2 more more JJR cord-022526-j9kg00qf 4236 3 severe severe JJ cord-022526-j9kg00qf 4236 4 cases case NNS cord-022526-j9kg00qf 4236 5 , , , cord-022526-j9kg00qf 4236 6 the the DT cord-022526-j9kg00qf 4236 7 acidic acidic JJ cord-022526-j9kg00qf 4236 8 contents content NNS cord-022526-j9kg00qf 4236 9 of of IN cord-022526-j9kg00qf 4236 10 the the DT cord-022526-j9kg00qf 4236 11 large large JJ cord-022526-j9kg00qf 4236 12 intestine intestine NN cord-022526-j9kg00qf 4236 13 are be VBP cord-022526-j9kg00qf 4236 14 toxic toxic JJ cord-022526-j9kg00qf 4236 15 to to IN cord-022526-j9kg00qf 4236 16 the the DT cord-022526-j9kg00qf 4236 17 mucosa mucosa NN cord-022526-j9kg00qf 4236 18 , , , cord-022526-j9kg00qf 4236 19 causing cause VBG cord-022526-j9kg00qf 4236 20 necrosis necrosis NN cord-022526-j9kg00qf 4236 21 of of IN cord-022526-j9kg00qf 4236 22 the the DT cord-022526-j9kg00qf 4236 23 mucosal mucosal JJ cord-022526-j9kg00qf 4236 24 tissues tissue NNS cord-022526-j9kg00qf 4236 25 , , , cord-022526-j9kg00qf 4236 26 similar similar JJ cord-022526-j9kg00qf 4236 27 to to IN cord-022526-j9kg00qf 4236 28 that that DT cord-022526-j9kg00qf 4236 29 occurring occur VBG cord-022526-j9kg00qf 4236 30 in in IN cord-022526-j9kg00qf 4236 31 ruminal ruminal JJ cord-022526-j9kg00qf 4236 32 acidosis acidosis NN cord-022526-j9kg00qf 4236 33 . . . cord-022526-j9kg00qf 4237 1 Mucosal Mucosal NNP cord-022526-j9kg00qf 4237 2 ulceration ulceration NN cord-022526-j9kg00qf 4237 3 allows allow VBZ cord-022526-j9kg00qf 4237 4 absorption absorption NN cord-022526-j9kg00qf 4237 5 of of IN cord-022526-j9kg00qf 4237 6 large large JJ cord-022526-j9kg00qf 4237 7 quantities quantity NNS cord-022526-j9kg00qf 4237 8 of of IN cord-022526-j9kg00qf 4237 9 endotoxin endotoxin NN cord-022526-j9kg00qf 4237 10 and and CC cord-022526-j9kg00qf 4237 11 lactic lactic JJ cord-022526-j9kg00qf 4237 12 acid acid NN cord-022526-j9kg00qf 4237 13 produced produce VBN cord-022526-j9kg00qf 4237 14 by by IN cord-022526-j9kg00qf 4237 15 the the DT cord-022526-j9kg00qf 4237 16 massive massive JJ cord-022526-j9kg00qf 4237 17 die die NN cord-022526-j9kg00qf 4237 18 - - HYPH cord-022526-j9kg00qf 4237 19 off off NN cord-022526-j9kg00qf 4237 20 of of IN cord-022526-j9kg00qf 4237 21 acid acid NN cord-022526-j9kg00qf 4237 22 - - HYPH cord-022526-j9kg00qf 4237 23 intolerant intolerant JJ cord-022526-j9kg00qf 4237 24 microbes microbe NNS cord-022526-j9kg00qf 4237 25 and and CC cord-022526-j9kg00qf 4237 26 fermentation fermentation NN cord-022526-j9kg00qf 4237 27 of of IN cord-022526-j9kg00qf 4237 28 soluble soluble JJ cord-022526-j9kg00qf 4237 29 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4237 30 , , , cord-022526-j9kg00qf 4237 31 normally normally RB cord-022526-j9kg00qf 4237 32 poorly poorly RB cord-022526-j9kg00qf 4237 33 absorbed absorb VBN cord-022526-j9kg00qf 4237 34 by by IN cord-022526-j9kg00qf 4237 35 intact intact JJ cord-022526-j9kg00qf 4237 36 mucosa mucosa JJ cord-022526-j9kg00qf 4237 37 . . . cord-022526-j9kg00qf 4238 1 209 209 CD cord-022526-j9kg00qf 4238 2 Systemic systemic JJ cord-022526-j9kg00qf 4238 3 inflammation inflammation NN cord-022526-j9kg00qf 4238 4 from from IN cord-022526-j9kg00qf 4238 5 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4238 6 may may MD cord-022526-j9kg00qf 4238 7 be be VB cord-022526-j9kg00qf 4238 8 overwhelming overwhelming JJ cord-022526-j9kg00qf 4238 9 , , , cord-022526-j9kg00qf 4238 10 and and CC cord-022526-j9kg00qf 4238 11 profound profound JJ cord-022526-j9kg00qf 4238 12 metabolic metabolic JJ cord-022526-j9kg00qf 4238 13 acidosis acidosis NN cord-022526-j9kg00qf 4238 14 may may MD cord-022526-j9kg00qf 4238 15 occur occur VB cord-022526-j9kg00qf 4238 16 . . . cord-022526-j9kg00qf 4239 1 Secretory secretory JJ cord-022526-j9kg00qf 4239 2 diarrhea diarrhea NN cord-022526-j9kg00qf 4239 3 caused cause VBN cord-022526-j9kg00qf 4239 4 by by IN cord-022526-j9kg00qf 4239 5 the the DT cord-022526-j9kg00qf 4239 6 direct direct JJ cord-022526-j9kg00qf 4239 7 effects effect NNS cord-022526-j9kg00qf 4239 8 of of IN cord-022526-j9kg00qf 4239 9 acid acid JJ cord-022526-j9kg00qf 4239 10 luminal luminal JJ cord-022526-j9kg00qf 4239 11 contents content NNS cord-022526-j9kg00qf 4239 12 on on IN cord-022526-j9kg00qf 4239 13 the the DT cord-022526-j9kg00qf 4239 14 mucosa mucosa NN cord-022526-j9kg00qf 4239 15 , , , cord-022526-j9kg00qf 4239 16 as as RB cord-022526-j9kg00qf 4239 17 well well RB cord-022526-j9kg00qf 4239 18 as as IN cord-022526-j9kg00qf 4239 19 the the DT cord-022526-j9kg00qf 4239 20 effects effect NNS cord-022526-j9kg00qf 4239 21 of of IN cord-022526-j9kg00qf 4239 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 4239 23 mediators mediator NNS cord-022526-j9kg00qf 4239 24 on on IN cord-022526-j9kg00qf 4239 25 enterocyte enterocyte NNP cord-022526-j9kg00qf 4239 26 secretion secretion NN cord-022526-j9kg00qf 4239 27 , , , cord-022526-j9kg00qf 4239 28 worsens worsen VBZ cord-022526-j9kg00qf 4239 29 the the DT cord-022526-j9kg00qf 4239 30 acidosis acidosis NN cord-022526-j9kg00qf 4239 31 and and CC cord-022526-j9kg00qf 4239 32 dehydration dehydration NN cord-022526-j9kg00qf 4239 33 . . . cord-022526-j9kg00qf 4240 1 Systemic systemic JJ cord-022526-j9kg00qf 4240 2 inflammation inflammation NN cord-022526-j9kg00qf 4240 3 from from IN cord-022526-j9kg00qf 4240 4 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4240 5 , , , cord-022526-j9kg00qf 4240 6 along along IN cord-022526-j9kg00qf 4240 7 with with IN cord-022526-j9kg00qf 4240 8 intestinal intestinal JJ cord-022526-j9kg00qf 4240 9 inflammation inflammation NN cord-022526-j9kg00qf 4240 10 , , , cord-022526-j9kg00qf 4240 11 adversely adversely RB cord-022526-j9kg00qf 4240 12 affects affect VBZ cord-022526-j9kg00qf 4240 13 intestinal intestinal JJ cord-022526-j9kg00qf 4240 14 motility motility NN cord-022526-j9kg00qf 4240 15 , , , cord-022526-j9kg00qf 4240 16 and and CC cord-022526-j9kg00qf 4240 17 ileus ileus NNP cord-022526-j9kg00qf 4240 18 develops develop VBZ cord-022526-j9kg00qf 4240 19 . . . cord-022526-j9kg00qf 4241 1 Ileus Ileus NNP cord-022526-j9kg00qf 4241 2 and and CC cord-022526-j9kg00qf 4241 3 gas gas NN cord-022526-j9kg00qf 4241 4 production production NN cord-022526-j9kg00qf 4241 5 from from IN cord-022526-j9kg00qf 4241 6 fermentation fermentation NN cord-022526-j9kg00qf 4241 7 of of IN cord-022526-j9kg00qf 4241 8 the the DT cord-022526-j9kg00qf 4241 9 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4241 10 may may MD cord-022526-j9kg00qf 4241 11 cause cause VB cord-022526-j9kg00qf 4241 12 severe severe JJ cord-022526-j9kg00qf 4241 13 distention distention NN cord-022526-j9kg00qf 4241 14 of of IN cord-022526-j9kg00qf 4241 15 the the DT cord-022526-j9kg00qf 4241 16 large large JJ cord-022526-j9kg00qf 4241 17 intestine intestine NN cord-022526-j9kg00qf 4241 18 and and CC cord-022526-j9kg00qf 4241 19 signs sign NNS cord-022526-j9kg00qf 4241 20 of of IN cord-022526-j9kg00qf 4241 21 abdominal abdominal JJ cord-022526-j9kg00qf 4241 22 pain pain NN cord-022526-j9kg00qf 4241 23 . . . cord-022526-j9kg00qf 4242 1 Laminitis Laminitis NNP cord-022526-j9kg00qf 4242 2 is be VBZ cord-022526-j9kg00qf 4242 3 a a DT cord-022526-j9kg00qf 4242 4 frequent frequent JJ cord-022526-j9kg00qf 4242 5 complication complication NN cord-022526-j9kg00qf 4242 6 of of IN cord-022526-j9kg00qf 4242 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4242 8 and and CC cord-022526-j9kg00qf 4242 9 lactic lactic JJ cord-022526-j9kg00qf 4242 10 acidosis acidosis NN cord-022526-j9kg00qf 4242 11 . . . cord-022526-j9kg00qf 4243 1 In in IN cord-022526-j9kg00qf 4243 2 fact fact NN cord-022526-j9kg00qf 4243 3 , , , cord-022526-j9kg00qf 4243 4 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4243 5 overload overload NN cord-022526-j9kg00qf 4243 6 is be VBZ cord-022526-j9kg00qf 4243 7 used use VBN cord-022526-j9kg00qf 4243 8 to to TO cord-022526-j9kg00qf 4243 9 induce induce VB cord-022526-j9kg00qf 4243 10 laminitis laminitis NN cord-022526-j9kg00qf 4243 11 as as IN cord-022526-j9kg00qf 4243 12 an an DT cord-022526-j9kg00qf 4243 13 experimental experimental JJ cord-022526-j9kg00qf 4243 14 model model NN cord-022526-j9kg00qf 4243 15 because because IN cord-022526-j9kg00qf 4243 16 of of IN cord-022526-j9kg00qf 4243 17 the the DT cord-022526-j9kg00qf 4243 18 consistency consistency NN cord-022526-j9kg00qf 4243 19 of of IN cord-022526-j9kg00qf 4243 20 the the DT cord-022526-j9kg00qf 4243 21 laminitis laminitis NN cord-022526-j9kg00qf 4243 22 produced produce VBN cord-022526-j9kg00qf 4243 23 . . . cord-022526-j9kg00qf 4244 1 [ [ -LRB- cord-022526-j9kg00qf 4244 2 207 207 CD cord-022526-j9kg00qf 4244 3 ] ] -RRB- cord-022526-j9kg00qf 4244 4 [ [ -LRB- cord-022526-j9kg00qf 4244 5 208 208 CD cord-022526-j9kg00qf 4244 6 ] ] -RRB- cord-022526-j9kg00qf 4244 7 [ [ -LRB- cord-022526-j9kg00qf 4244 8 209 209 CD cord-022526-j9kg00qf 4244 9 ] ] -RRB- cord-022526-j9kg00qf 4244 10 _SP cord-022526-j9kg00qf 4244 11 Clinical clinical JJ cord-022526-j9kg00qf 4244 12 signs sign NNS cord-022526-j9kg00qf 4244 13 of of IN cord-022526-j9kg00qf 4244 14 colitis colitis NN cord-022526-j9kg00qf 4244 15 from from IN cord-022526-j9kg00qf 4244 16 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4244 17 overload overload NN cord-022526-j9kg00qf 4244 18 can can MD cord-022526-j9kg00qf 4244 19 vary vary VB cord-022526-j9kg00qf 4244 20 according accord VBG cord-022526-j9kg00qf 4244 21 to to IN cord-022526-j9kg00qf 4244 22 the the DT cord-022526-j9kg00qf 4244 23 amount amount NN cord-022526-j9kg00qf 4244 24 of of IN cord-022526-j9kg00qf 4244 25 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4244 26 ingested ingest VBN cord-022526-j9kg00qf 4244 27 and and CC cord-022526-j9kg00qf 4244 28 accommodation accommodation NN cord-022526-j9kg00qf 4244 29 of of IN cord-022526-j9kg00qf 4244 30 the the DT cord-022526-j9kg00qf 4244 31 flora flora NNS cord-022526-j9kg00qf 4244 32 to to IN cord-022526-j9kg00qf 4244 33 a a DT cord-022526-j9kg00qf 4244 34 high high JJ cord-022526-j9kg00qf 4244 35 - - HYPH cord-022526-j9kg00qf 4244 36 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4244 37 diet diet NN cord-022526-j9kg00qf 4244 38 . . . cord-022526-j9kg00qf 4245 1 Mild mild JJ cord-022526-j9kg00qf 4245 2 cases case NNS cord-022526-j9kg00qf 4245 3 may may MD cord-022526-j9kg00qf 4245 4 result result VB cord-022526-j9kg00qf 4245 5 in in IN cord-022526-j9kg00qf 4245 6 a a DT cord-022526-j9kg00qf 4245 7 transient transient JJ cord-022526-j9kg00qf 4245 8 osmotic osmotic JJ cord-022526-j9kg00qf 4245 9 diarrhea diarrhea NN cord-022526-j9kg00qf 4245 10 with with IN cord-022526-j9kg00qf 4245 11 no no DT cord-022526-j9kg00qf 4245 12 systemic systemic JJ cord-022526-j9kg00qf 4245 13 effects effect NNS cord-022526-j9kg00qf 4245 14 . . . cord-022526-j9kg00qf 4246 1 More More JJR cord-022526-j9kg00qf 4246 2 severe severe JJ cord-022526-j9kg00qf 4246 3 cases case NNS cord-022526-j9kg00qf 4246 4 are be VBP cord-022526-j9kg00qf 4246 5 characterized characterize VBN cord-022526-j9kg00qf 4246 6 by by IN cord-022526-j9kg00qf 4246 7 signs sign NNS cord-022526-j9kg00qf 4246 8 similar similar JJ cord-022526-j9kg00qf 4246 9 to to IN cord-022526-j9kg00qf 4246 10 those those DT cord-022526-j9kg00qf 4246 11 described describe VBN cord-022526-j9kg00qf 4246 12 for for IN cord-022526-j9kg00qf 4246 13 other other JJ cord-022526-j9kg00qf 4246 14 forms form NNS cord-022526-j9kg00qf 4246 15 of of IN cord-022526-j9kg00qf 4246 16 colitis colitis NN cord-022526-j9kg00qf 4246 17 , , , cord-022526-j9kg00qf 4246 18 including include VBG cord-022526-j9kg00qf 4246 19 abdominal abdominal JJ cord-022526-j9kg00qf 4246 20 pain pain NN cord-022526-j9kg00qf 4246 21 , , , cord-022526-j9kg00qf 4246 22 moderate moderate JJ cord-022526-j9kg00qf 4246 23 to to IN cord-022526-j9kg00qf 4246 24 severe severe JJ cord-022526-j9kg00qf 4246 25 diarrhea diarrhea NN cord-022526-j9kg00qf 4246 26 , , , cord-022526-j9kg00qf 4246 27 and and CC cord-022526-j9kg00qf 4246 28 dehydration dehydration NN cord-022526-j9kg00qf 4246 29 . . . cord-022526-j9kg00qf 4247 1 Signs sign NNS cord-022526-j9kg00qf 4247 2 of of IN cord-022526-j9kg00qf 4247 3 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4247 4 and and CC cord-022526-j9kg00qf 4247 5 sepsis sepsis NN cord-022526-j9kg00qf 4247 6 are be VBP cord-022526-j9kg00qf 4247 7 frequently frequently RB cord-022526-j9kg00qf 4247 8 present present JJ cord-022526-j9kg00qf 4247 9 in in IN cord-022526-j9kg00qf 4247 10 severe severe JJ cord-022526-j9kg00qf 4247 11 cases case NNS cord-022526-j9kg00qf 4247 12 . . . cord-022526-j9kg00qf 4248 1 Elevated elevated JJ cord-022526-j9kg00qf 4248 2 heart heart NN cord-022526-j9kg00qf 4248 3 and and CC cord-022526-j9kg00qf 4248 4 respiratory respiratory JJ cord-022526-j9kg00qf 4248 5 rates rate NNS cord-022526-j9kg00qf 4248 6 are be VBP cord-022526-j9kg00qf 4248 7 common common JJ cord-022526-j9kg00qf 4248 8 , , , cord-022526-j9kg00qf 4248 9 with with IN cord-022526-j9kg00qf 4248 10 peripheral peripheral JJ cord-022526-j9kg00qf 4248 11 vasoconstriction vasoconstriction NN cord-022526-j9kg00qf 4248 12 early early RB cord-022526-j9kg00qf 4248 13 in in IN cord-022526-j9kg00qf 4248 14 the the DT cord-022526-j9kg00qf 4248 15 disease disease NN cord-022526-j9kg00qf 4248 16 , , , cord-022526-j9kg00qf 4248 17 followed follow VBN cord-022526-j9kg00qf 4248 18 by by IN cord-022526-j9kg00qf 4248 19 peripheral peripheral JJ cord-022526-j9kg00qf 4248 20 vasodilation vasodilation NN cord-022526-j9kg00qf 4248 21 as as IN cord-022526-j9kg00qf 4248 22 the the DT cord-022526-j9kg00qf 4248 23 disease disease NN cord-022526-j9kg00qf 4248 24 progresses progress VBZ cord-022526-j9kg00qf 4248 25 . . . cord-022526-j9kg00qf 4249 1 Depression depression NN cord-022526-j9kg00qf 4249 2 may may MD cord-022526-j9kg00qf 4249 3 be be VB cord-022526-j9kg00qf 4249 4 profound profound JJ cord-022526-j9kg00qf 4249 5 from from IN cord-022526-j9kg00qf 4249 6 metabolic metabolic JJ cord-022526-j9kg00qf 4249 7 acidosis acidosis NN cord-022526-j9kg00qf 4249 8 and and CC cord-022526-j9kg00qf 4249 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4249 10 . . . cord-022526-j9kg00qf 4250 1 Abdominal abdominal JJ cord-022526-j9kg00qf 4250 2 auscultation auscultation NN cord-022526-j9kg00qf 4250 3 and and CC cord-022526-j9kg00qf 4250 4 percussion percussion NN cord-022526-j9kg00qf 4250 5 may may MD cord-022526-j9kg00qf 4250 6 reveal reveal VB cord-022526-j9kg00qf 4250 7 ileus ileus NNP cord-022526-j9kg00qf 4250 8 and and CC cord-022526-j9kg00qf 4250 9 intestinal intestinal JJ cord-022526-j9kg00qf 4250 10 tympany tympany NNP cord-022526-j9kg00qf 4250 11 . . . cord-022526-j9kg00qf 4251 1 Nasogastric nasogastric NN cord-022526-j9kg00qf 4251 2 intubation intubation NN cord-022526-j9kg00qf 4251 3 may may MD cord-022526-j9kg00qf 4251 4 yield yield VB cord-022526-j9kg00qf 4251 5 significant significant JJ cord-022526-j9kg00qf 4251 6 gastric gastric JJ cord-022526-j9kg00qf 4251 7 acidic acidic JJ cord-022526-j9kg00qf 4251 8 reflux reflux NN cord-022526-j9kg00qf 4251 9 . . . cord-022526-j9kg00qf 4252 1 One one CD cord-022526-j9kg00qf 4252 2 may may MD cord-022526-j9kg00qf 4252 3 note note VB cord-022526-j9kg00qf 4252 4 particles particle NNS cord-022526-j9kg00qf 4252 5 of of IN cord-022526-j9kg00qf 4252 6 grain grain NN cord-022526-j9kg00qf 4252 7 in in IN cord-022526-j9kg00qf 4252 8 the the DT cord-022526-j9kg00qf 4252 9 gastric gastric JJ cord-022526-j9kg00qf 4252 10 reflux reflux NN cord-022526-j9kg00qf 4252 11 and and CC cord-022526-j9kg00qf 4252 12 the the DT cord-022526-j9kg00qf 4252 13 feces fece NNS cord-022526-j9kg00qf 4252 14 , , , cord-022526-j9kg00qf 4252 15 if if IN cord-022526-j9kg00qf 4252 16 grain grain NN cord-022526-j9kg00qf 4252 17 overload overload NN cord-022526-j9kg00qf 4252 18 is be VBZ cord-022526-j9kg00qf 4252 19 the the DT cord-022526-j9kg00qf 4252 20 source source NN cord-022526-j9kg00qf 4252 21 of of IN cord-022526-j9kg00qf 4252 22 the the DT cord-022526-j9kg00qf 4252 23 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4252 24 overload overload NN cord-022526-j9kg00qf 4252 25 . . . cord-022526-j9kg00qf 4253 1 Laminitis Laminitis NNP cord-022526-j9kg00qf 4253 2 may may MD cord-022526-j9kg00qf 4253 3 complicate complicate VB cord-022526-j9kg00qf 4253 4 mild mild JJ cord-022526-j9kg00qf 4253 5 and and CC cord-022526-j9kg00qf 4253 6 severe severe JJ cord-022526-j9kg00qf 4253 7 cases case NNS cord-022526-j9kg00qf 4253 8 of of IN cord-022526-j9kg00qf 4253 9 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4253 10 overload overload NN cord-022526-j9kg00qf 4253 11 , , , cord-022526-j9kg00qf 4253 12 especially especially RB cord-022526-j9kg00qf 4253 13 if if IN cord-022526-j9kg00qf 4253 14 the the DT cord-022526-j9kg00qf 4253 15 animal animal NN cord-022526-j9kg00qf 4253 16 has have VBZ cord-022526-j9kg00qf 4253 17 had have VBN cord-022526-j9kg00qf 4253 18 previous previous JJ cord-022526-j9kg00qf 4253 19 bouts bout NNS cord-022526-j9kg00qf 4253 20 of of IN cord-022526-j9kg00qf 4253 21 laminitis laminitis NN cord-022526-j9kg00qf 4253 22 . . . cord-022526-j9kg00qf 4254 1 Hematologic Hematologic NNP cord-022526-j9kg00qf 4254 2 abnormalities abnormality NNS cord-022526-j9kg00qf 4254 3 include include VBP cord-022526-j9kg00qf 4254 4 neutropenia neutropenia NN cord-022526-j9kg00qf 4254 5 and and CC cord-022526-j9kg00qf 4254 6 leukopenia leukopenia NN cord-022526-j9kg00qf 4254 7 . . . cord-022526-j9kg00qf 4255 1 Severe severe JJ cord-022526-j9kg00qf 4255 2 dehydration dehydration NN cord-022526-j9kg00qf 4255 3 may may MD cord-022526-j9kg00qf 4255 4 result result VB cord-022526-j9kg00qf 4255 5 in in IN cord-022526-j9kg00qf 4255 6 profound profound JJ cord-022526-j9kg00qf 4255 7 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 4255 8 . . . cord-022526-j9kg00qf 4256 1 Protein protein NN cord-022526-j9kg00qf 4256 2 loss loss NN cord-022526-j9kg00qf 4256 3 later later RB cord-022526-j9kg00qf 4256 4 in in IN cord-022526-j9kg00qf 4256 5 the the DT cord-022526-j9kg00qf 4256 6 course course NN cord-022526-j9kg00qf 4256 7 of of IN cord-022526-j9kg00qf 4256 8 disease disease NN cord-022526-j9kg00qf 4256 9 may may MD cord-022526-j9kg00qf 4256 10 result result VB cord-022526-j9kg00qf 4256 11 in in IN cord-022526-j9kg00qf 4256 12 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 4256 13 . . . cord-022526-j9kg00qf 4257 1 Serum serum NN cord-022526-j9kg00qf 4257 2 biochemical biochemical JJ cord-022526-j9kg00qf 4257 3 abnormalities abnormality NNS cord-022526-j9kg00qf 4257 4 include include VBP cord-022526-j9kg00qf 4257 5 azotemia azotemia NN cord-022526-j9kg00qf 4257 6 , , , cord-022526-j9kg00qf 4257 7 elevated elevate VBN cord-022526-j9kg00qf 4257 8 hepatocellular hepatocellular JJ cord-022526-j9kg00qf 4257 9 enzyme enzyme NN cord-022526-j9kg00qf 4257 10 activity activity NN cord-022526-j9kg00qf 4257 11 , , , cord-022526-j9kg00qf 4257 12 hyponatremia hyponatremia NN cord-022526-j9kg00qf 4257 13 , , , cord-022526-j9kg00qf 4257 14 and and CC cord-022526-j9kg00qf 4257 15 hypokalemia hypokalemia NN cord-022526-j9kg00qf 4257 16 . . . cord-022526-j9kg00qf 4258 1 Severe severe JJ cord-022526-j9kg00qf 4258 2 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4258 3 and and CC cord-022526-j9kg00qf 4258 4 metabolic metabolic JJ cord-022526-j9kg00qf 4258 5 acidosis acidosis NN cord-022526-j9kg00qf 4258 6 are be VBP cord-022526-j9kg00qf 4258 7 characteristic characteristic JJ cord-022526-j9kg00qf 4258 8 of of IN cord-022526-j9kg00qf 4258 9 the the DT cord-022526-j9kg00qf 4258 10 disease disease NN cord-022526-j9kg00qf 4258 11 . . . cord-022526-j9kg00qf 4259 1 Serum serum NN cord-022526-j9kg00qf 4259 2 lactate lactate NN cord-022526-j9kg00qf 4259 3 concentrations concentration NNS cord-022526-j9kg00qf 4259 4 are be VBP cord-022526-j9kg00qf 4259 5 elevated elevate VBN cord-022526-j9kg00qf 4259 6 in in IN cord-022526-j9kg00qf 4259 7 the the DT cord-022526-j9kg00qf 4259 8 absence absence NN cord-022526-j9kg00qf 4259 9 of of IN cord-022526-j9kg00qf 4259 10 evidence evidence NN cord-022526-j9kg00qf 4259 11 of of IN cord-022526-j9kg00qf 4259 12 intestinal intestinal JJ cord-022526-j9kg00qf 4259 13 strangulation strangulation NN cord-022526-j9kg00qf 4259 14 or or CC cord-022526-j9kg00qf 4259 15 infarction infarction NN cord-022526-j9kg00qf 4259 16 . . . cord-022526-j9kg00qf 4260 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 4260 2 fluid fluid JJ cord-022526-j9kg00qf 4260 3 analysis analysis NN cord-022526-j9kg00qf 4260 4 often often RB cord-022526-j9kg00qf 4260 5 reveals reveal VBZ cord-022526-j9kg00qf 4260 6 no no DT cord-022526-j9kg00qf 4260 7 abnormalities abnormality NNS cord-022526-j9kg00qf 4260 8 . . . cord-022526-j9kg00qf 4261 1 Sand sand NN cord-022526-j9kg00qf 4261 2 enteropathy enteropathy NNP cord-022526-j9kg00qf 4261 3 is be VBZ cord-022526-j9kg00qf 4261 4 described describe VBN cord-022526-j9kg00qf 4261 5 in in IN cord-022526-j9kg00qf 4261 6 more more JJR cord-022526-j9kg00qf 4261 7 detail detail NN cord-022526-j9kg00qf 4261 8 under under IN cord-022526-j9kg00qf 4261 9 the the DT cord-022526-j9kg00qf 4261 10 heading heading NN cord-022526-j9kg00qf 4261 11 of of IN cord-022526-j9kg00qf 4261 12 obstructive obstructive JJ cord-022526-j9kg00qf 4261 13 diseases disease NNS cord-022526-j9kg00qf 4261 14 , , , cord-022526-j9kg00qf 4261 15 because because IN cord-022526-j9kg00qf 4261 16 acute acute JJ cord-022526-j9kg00qf 4261 17 obstruction obstruction NN cord-022526-j9kg00qf 4261 18 is be VBZ cord-022526-j9kg00qf 4261 19 often often RB cord-022526-j9kg00qf 4261 20 associated associate VBN cord-022526-j9kg00qf 4261 21 with with IN cord-022526-j9kg00qf 4261 22 abnormally abnormally RB cord-022526-j9kg00qf 4261 23 large large JJ cord-022526-j9kg00qf 4261 24 amounts amount NNS cord-022526-j9kg00qf 4261 25 of of IN cord-022526-j9kg00qf 4261 26 sand sand NN cord-022526-j9kg00qf 4261 27 in in IN cord-022526-j9kg00qf 4261 28 the the DT cord-022526-j9kg00qf 4261 29 large large JJ cord-022526-j9kg00qf 4261 30 intestine intestine NN cord-022526-j9kg00qf 4261 31 . . . cord-022526-j9kg00qf 4262 1 210 210 CD cord-022526-j9kg00qf 4263 1 However however RB cord-022526-j9kg00qf 4263 2 , , , cord-022526-j9kg00qf 4263 3 chronic chronic JJ cord-022526-j9kg00qf 4263 4 sand sand NN cord-022526-j9kg00qf 4263 5 - - HYPH cord-022526-j9kg00qf 4263 6 induced induce VBN cord-022526-j9kg00qf 4263 7 diarrhea diarrhea NN cord-022526-j9kg00qf 4263 8 is be VBZ cord-022526-j9kg00qf 4263 9 a a DT cord-022526-j9kg00qf 4263 10 distinct distinct JJ cord-022526-j9kg00qf 4263 11 syndrome syndrome NN cord-022526-j9kg00qf 4263 12 that that WDT cord-022526-j9kg00qf 4263 13 can can MD cord-022526-j9kg00qf 4263 14 occur occur VB cord-022526-j9kg00qf 4263 15 at at IN cord-022526-j9kg00qf 4263 16 any any DT cord-022526-j9kg00qf 4263 17 age age NN cord-022526-j9kg00qf 4263 18 from from IN cord-022526-j9kg00qf 4263 19 abnormal abnormal JJ cord-022526-j9kg00qf 4263 20 accumulation accumulation NN cord-022526-j9kg00qf 4263 21 of of IN cord-022526-j9kg00qf 4263 22 sand sand NN cord-022526-j9kg00qf 4263 23 in in IN cord-022526-j9kg00qf 4263 24 the the DT cord-022526-j9kg00qf 4263 25 large large JJ cord-022526-j9kg00qf 4263 26 intestine intestine NN cord-022526-j9kg00qf 4263 27 . . . cord-022526-j9kg00qf 4264 1 211 211 CD cord-022526-j9kg00qf 4264 2 , , , cord-022526-j9kg00qf 4264 3 212 212 CD cord-022526-j9kg00qf 4264 4 Chronic chronic JJ cord-022526-j9kg00qf 4264 5 diarrhea diarrhea NN cord-022526-j9kg00qf 4264 6 and and CC cord-022526-j9kg00qf 4264 7 signs sign NNS cord-022526-j9kg00qf 4264 8 of of IN cord-022526-j9kg00qf 4264 9 colic colic NN cord-022526-j9kg00qf 4264 10 may may MD cord-022526-j9kg00qf 4264 11 occur occur VB cord-022526-j9kg00qf 4264 12 without without IN cord-022526-j9kg00qf 4264 13 obstruction obstruction NN cord-022526-j9kg00qf 4264 14 . . . cord-022526-j9kg00qf 4265 1 The the DT cord-022526-j9kg00qf 4265 2 pathogenesis pathogenesis NN cord-022526-j9kg00qf 4265 3 of of IN cord-022526-j9kg00qf 4265 4 sand sand NN cord-022526-j9kg00qf 4265 5 accumulation accumulation NN cord-022526-j9kg00qf 4265 6 in in IN cord-022526-j9kg00qf 4265 7 individual individual JJ cord-022526-j9kg00qf 4265 8 horses horse NNS cord-022526-j9kg00qf 4265 9 , , , cord-022526-j9kg00qf 4265 10 other other JJ cord-022526-j9kg00qf 4265 11 than than IN cord-022526-j9kg00qf 4265 12 simple simple JJ cord-022526-j9kg00qf 4265 13 ingestion ingestion NN cord-022526-j9kg00qf 4265 14 of of IN cord-022526-j9kg00qf 4265 15 large large JJ cord-022526-j9kg00qf 4265 16 quantities quantity NNS cord-022526-j9kg00qf 4265 17 , , , cord-022526-j9kg00qf 4265 18 is be VBZ cord-022526-j9kg00qf 4265 19 unclear unclear JJ cord-022526-j9kg00qf 4265 20 . . . cord-022526-j9kg00qf 4266 1 Presumably presumably RB cord-022526-j9kg00qf 4266 2 the the DT cord-022526-j9kg00qf 4266 3 sand sand NN cord-022526-j9kg00qf 4266 4 causes cause VBZ cord-022526-j9kg00qf 4266 5 irritation irritation NN cord-022526-j9kg00qf 4266 6 and and CC cord-022526-j9kg00qf 4266 7 may may MD cord-022526-j9kg00qf 4266 8 disrupt disrupt VB cord-022526-j9kg00qf 4266 9 motility motility NN cord-022526-j9kg00qf 4266 10 , , , cord-022526-j9kg00qf 4266 11 leading lead VBG cord-022526-j9kg00qf 4266 12 to to IN cord-022526-j9kg00qf 4266 13 diarrhea diarrhea NN cord-022526-j9kg00qf 4266 14 . . . cord-022526-j9kg00qf 4267 1 The the DT cord-022526-j9kg00qf 4267 2 diarrhea diarrhea NN cord-022526-j9kg00qf 4267 3 is be VBZ cord-022526-j9kg00qf 4267 4 usually usually RB cord-022526-j9kg00qf 4267 5 not not RB cord-022526-j9kg00qf 4267 6 severe severe JJ cord-022526-j9kg00qf 4267 7 and and CC cord-022526-j9kg00qf 4267 8 dehydrating dehydrate VBG cord-022526-j9kg00qf 4267 9 and and CC cord-022526-j9kg00qf 4267 10 may may MD cord-022526-j9kg00qf 4267 11 be be VB cord-022526-j9kg00qf 4267 12 intermittent intermittent JJ cord-022526-j9kg00qf 4267 13 . . . cord-022526-j9kg00qf 4268 1 Weight weight NN cord-022526-j9kg00qf 4268 2 loss loss NN cord-022526-j9kg00qf 4268 3 is be VBZ cord-022526-j9kg00qf 4268 4 characteristic characteristic JJ cord-022526-j9kg00qf 4268 5 and and CC cord-022526-j9kg00qf 4268 6 can can MD cord-022526-j9kg00qf 4268 7 be be VB cord-022526-j9kg00qf 4268 8 severe severe JJ cord-022526-j9kg00qf 4268 9 in in IN cord-022526-j9kg00qf 4268 10 some some DT cord-022526-j9kg00qf 4268 11 cases case NNS cord-022526-j9kg00qf 4268 12 . . . cord-022526-j9kg00qf 4269 1 Complications complication NNS cord-022526-j9kg00qf 4269 2 may may MD cord-022526-j9kg00qf 4269 3 occur occur VB cord-022526-j9kg00qf 4269 4 such such JJ cord-022526-j9kg00qf 4269 5 as as IN cord-022526-j9kg00qf 4269 6 peritonitis peritonitis NN cord-022526-j9kg00qf 4269 7 and and CC cord-022526-j9kg00qf 4269 8 acute acute JJ cord-022526-j9kg00qf 4269 9 obstruction obstruction NN cord-022526-j9kg00qf 4269 10 . . . cord-022526-j9kg00qf 4270 1 211 211 CD cord-022526-j9kg00qf 4270 2 Diagnosis diagnosis NN cord-022526-j9kg00qf 4270 3 usually usually RB cord-022526-j9kg00qf 4270 4 is be VBZ cord-022526-j9kg00qf 4270 5 based base VBN cord-022526-j9kg00qf 4270 6 on on IN cord-022526-j9kg00qf 4270 7 finding find VBG cord-022526-j9kg00qf 4270 8 abnormal abnormal JJ cord-022526-j9kg00qf 4270 9 amounts amount NNS cord-022526-j9kg00qf 4270 10 of of IN cord-022526-j9kg00qf 4270 11 sand sand NN cord-022526-j9kg00qf 4270 12 in in IN cord-022526-j9kg00qf 4270 13 the the DT cord-022526-j9kg00qf 4270 14 feces fece NNS cord-022526-j9kg00qf 4270 15 . . . cord-022526-j9kg00qf 4271 1 Because because IN cord-022526-j9kg00qf 4271 2 sand sand NN cord-022526-j9kg00qf 4271 3 - - HYPH cord-022526-j9kg00qf 4271 4 induced induce VBN cord-022526-j9kg00qf 4271 5 chronic chronic JJ cord-022526-j9kg00qf 4271 6 diarrhea diarrhea NN cord-022526-j9kg00qf 4271 7 is be VBZ cord-022526-j9kg00qf 4271 8 associated associate VBN cord-022526-j9kg00qf 4271 9 primarily primarily RB cord-022526-j9kg00qf 4271 10 with with IN cord-022526-j9kg00qf 4271 11 sand sand NN cord-022526-j9kg00qf 4271 12 accumulation accumulation NN cord-022526-j9kg00qf 4271 13 in in IN cord-022526-j9kg00qf 4271 14 the the DT cord-022526-j9kg00qf 4271 15 ventral ventral JJ cord-022526-j9kg00qf 4271 16 colon colon NN cord-022526-j9kg00qf 4271 17 , , , cord-022526-j9kg00qf 4271 18 auscultation auscultation NN cord-022526-j9kg00qf 4271 19 of of IN cord-022526-j9kg00qf 4271 20 the the DT cord-022526-j9kg00qf 4271 21 ventral ventral JJ cord-022526-j9kg00qf 4271 22 abdomen abdomen NN cord-022526-j9kg00qf 4271 23 immediately immediately RB cord-022526-j9kg00qf 4271 24 behind behind IN cord-022526-j9kg00qf 4271 25 the the DT cord-022526-j9kg00qf 4271 26 xiphoid xiphoid NN cord-022526-j9kg00qf 4271 27 process process NN cord-022526-j9kg00qf 4271 28 may may MD cord-022526-j9kg00qf 4271 29 reveal reveal VB cord-022526-j9kg00qf 4271 30 characteristic characteristic JJ cord-022526-j9kg00qf 4271 31 sand sand NN cord-022526-j9kg00qf 4271 32 sounds sound VBZ cord-022526-j9kg00qf 4271 33 . . . cord-022526-j9kg00qf 4272 1 213 213 CD cord-022526-j9kg00qf 4273 1 This this DT cord-022526-j9kg00qf 4273 2 technique technique NN cord-022526-j9kg00qf 4273 3 is be VBZ cord-022526-j9kg00qf 4273 4 only only RB cord-022526-j9kg00qf 4273 5 sensitive sensitive JJ cord-022526-j9kg00qf 4273 6 if if IN cord-022526-j9kg00qf 4273 7 peristalsis peristalsis NN cord-022526-j9kg00qf 4273 8 is be VBZ cord-022526-j9kg00qf 4273 9 present present JJ cord-022526-j9kg00qf 4273 10 . . . cord-022526-j9kg00qf 4274 1 Ultrasonography Ultrasonography NNP cord-022526-j9kg00qf 4274 2 also also RB cord-022526-j9kg00qf 4274 3 may may MD cord-022526-j9kg00qf 4274 4 be be VB cord-022526-j9kg00qf 4274 5 useful useful JJ cord-022526-j9kg00qf 4274 6 to to TO cord-022526-j9kg00qf 4274 7 identify identify VB cord-022526-j9kg00qf 4274 8 sand sand NN cord-022526-j9kg00qf 4274 9 in in IN cord-022526-j9kg00qf 4274 10 the the DT cord-022526-j9kg00qf 4274 11 ventral ventral JJ cord-022526-j9kg00qf 4274 12 colon colon NN cord-022526-j9kg00qf 4274 13 but but CC cord-022526-j9kg00qf 4274 14 is be VBZ cord-022526-j9kg00qf 4274 15 not not RB cord-022526-j9kg00qf 4274 16 useful useful JJ cord-022526-j9kg00qf 4274 17 to to TO cord-022526-j9kg00qf 4274 18 quantitate quantitate VB cord-022526-j9kg00qf 4274 19 the the DT cord-022526-j9kg00qf 4274 20 amount amount NN cord-022526-j9kg00qf 4274 21 of of IN cord-022526-j9kg00qf 4274 22 sand sand NN cord-022526-j9kg00qf 4274 23 . . . cord-022526-j9kg00qf 4275 1 Occasionally occasionally RB cord-022526-j9kg00qf 4275 2 , , , cord-022526-j9kg00qf 4275 3 radiography radiography NN cord-022526-j9kg00qf 4275 4 may may MD cord-022526-j9kg00qf 4275 5 be be VB cord-022526-j9kg00qf 4275 6 required require VBN cord-022526-j9kg00qf 4275 7 to to TO cord-022526-j9kg00qf 4275 8 detect detect VB cord-022526-j9kg00qf 4275 9 sand sand NN cord-022526-j9kg00qf 4275 10 in in IN cord-022526-j9kg00qf 4275 11 the the DT cord-022526-j9kg00qf 4275 12 colon colon NN cord-022526-j9kg00qf 4275 13 . . . cord-022526-j9kg00qf 4276 1 211 211 CD cord-022526-j9kg00qf 4277 1 The the DT cord-022526-j9kg00qf 4277 2 principles principle NNS cord-022526-j9kg00qf 4277 3 of of IN cord-022526-j9kg00qf 4277 4 therapy therapy NN cord-022526-j9kg00qf 4277 5 of of IN cord-022526-j9kg00qf 4277 6 acute acute JJ cord-022526-j9kg00qf 4277 7 diarrhea diarrhea NN cord-022526-j9kg00qf 4277 8 from from IN cord-022526-j9kg00qf 4277 9 colitis colitis NN cord-022526-j9kg00qf 4277 10 are be VBP cord-022526-j9kg00qf 4277 11 similar similar JJ cord-022526-j9kg00qf 4277 12 regardless regardless RB cord-022526-j9kg00qf 4277 13 of of IN cord-022526-j9kg00qf 4277 14 the the DT cord-022526-j9kg00qf 4277 15 cause cause NN cord-022526-j9kg00qf 4277 16 and and CC cord-022526-j9kg00qf 4277 17 include include VBP cord-022526-j9kg00qf 4277 18 replacement replacement NN cord-022526-j9kg00qf 4277 19 of of IN cord-022526-j9kg00qf 4277 20 fluid fluid JJ cord-022526-j9kg00qf 4277 21 and and CC cord-022526-j9kg00qf 4277 22 electrolyte electrolyte JJ cord-022526-j9kg00qf 4277 23 losses loss NNS cord-022526-j9kg00qf 4277 24 , , , cord-022526-j9kg00qf 4277 25 control control NN cord-022526-j9kg00qf 4277 26 of of IN cord-022526-j9kg00qf 4277 27 colonic colonic JJ cord-022526-j9kg00qf 4277 28 inflammation inflammation NN cord-022526-j9kg00qf 4277 29 and and CC cord-022526-j9kg00qf 4277 30 reduction reduction NN cord-022526-j9kg00qf 4277 31 of of IN cord-022526-j9kg00qf 4277 32 fluid fluid JJ cord-022526-j9kg00qf 4277 33 secretion secretion NN cord-022526-j9kg00qf 4277 34 , , , cord-022526-j9kg00qf 4277 35 promotion promotion NN cord-022526-j9kg00qf 4277 36 of of IN cord-022526-j9kg00qf 4277 37 mucosal mucosal JJ cord-022526-j9kg00qf 4277 38 repair repair NN cord-022526-j9kg00qf 4277 39 , , , cord-022526-j9kg00qf 4277 40 control control NN cord-022526-j9kg00qf 4277 41 of of IN cord-022526-j9kg00qf 4277 42 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4277 43 and and CC cord-022526-j9kg00qf 4277 44 sepsis sepsis NN cord-022526-j9kg00qf 4277 45 , , , cord-022526-j9kg00qf 4277 46 and and CC cord-022526-j9kg00qf 4277 47 reestablishment reestablishment NN cord-022526-j9kg00qf 4277 48 of of IN cord-022526-j9kg00qf 4277 49 normal normal JJ cord-022526-j9kg00qf 4277 50 flora flora NNS cord-022526-j9kg00qf 4277 51 . . . cord-022526-j9kg00qf 4278 1 This this DT cord-022526-j9kg00qf 4278 2 section section NN cord-022526-j9kg00qf 4278 3 focuses focus VBZ cord-022526-j9kg00qf 4278 4 on on IN cord-022526-j9kg00qf 4278 5 a a DT cord-022526-j9kg00qf 4278 6 review review NN cord-022526-j9kg00qf 4278 7 the the DT cord-022526-j9kg00qf 4278 8 principles principle NNS cord-022526-j9kg00qf 4278 9 of of IN cord-022526-j9kg00qf 4278 10 therapy therapy NN cord-022526-j9kg00qf 4278 11 with with IN cord-022526-j9kg00qf 4278 12 references reference NNS cord-022526-j9kg00qf 4278 13 to to IN cord-022526-j9kg00qf 4278 14 specific specific JJ cord-022526-j9kg00qf 4278 15 therapies therapy NNS cord-022526-j9kg00qf 4278 16 for for IN cord-022526-j9kg00qf 4278 17 particular particular JJ cord-022526-j9kg00qf 4278 18 causes cause NNS cord-022526-j9kg00qf 4278 19 as as IN cord-022526-j9kg00qf 4278 20 they -PRON- PRP cord-022526-j9kg00qf 4278 21 arise arise VBP cord-022526-j9kg00qf 4278 22 . . . cord-022526-j9kg00qf 4279 1 Replacement replacement NN cord-022526-j9kg00qf 4279 2 of of IN cord-022526-j9kg00qf 4279 3 fluid fluid JJ cord-022526-j9kg00qf 4279 4 and and CC cord-022526-j9kg00qf 4279 5 electrolyte electrolyte JJ cord-022526-j9kg00qf 4279 6 losses loss NNS cord-022526-j9kg00qf 4279 7 is be VBZ cord-022526-j9kg00qf 4279 8 of of IN cord-022526-j9kg00qf 4279 9 primary primary JJ cord-022526-j9kg00qf 4279 10 concern concern NN cord-022526-j9kg00qf 4279 11 in in IN cord-022526-j9kg00qf 4279 12 treating treat VBG cord-022526-j9kg00qf 4279 13 horses horse NNS cord-022526-j9kg00qf 4279 14 with with IN cord-022526-j9kg00qf 4279 15 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4279 16 . . . cord-022526-j9kg00qf 4280 1 Depending depend VBG cord-022526-j9kg00qf 4280 2 on on IN cord-022526-j9kg00qf 4280 3 the the DT cord-022526-j9kg00qf 4280 4 severity severity NN cord-022526-j9kg00qf 4280 5 of of IN cord-022526-j9kg00qf 4280 6 the the DT cord-022526-j9kg00qf 4280 7 disease disease NN cord-022526-j9kg00qf 4280 8 , , , cord-022526-j9kg00qf 4280 9 fluid fluid JJ cord-022526-j9kg00qf 4280 10 losses loss NNS cord-022526-j9kg00qf 4280 11 may may MD cord-022526-j9kg00qf 4280 12 be be VB cord-022526-j9kg00qf 4280 13 minimal minimal JJ cord-022526-j9kg00qf 4280 14 or or CC cord-022526-j9kg00qf 4280 15 massive massive JJ cord-022526-j9kg00qf 4280 16 . . . cord-022526-j9kg00qf 4281 1 One one PRP cord-022526-j9kg00qf 4281 2 can can MD cord-022526-j9kg00qf 4281 3 administer administer VB cord-022526-j9kg00qf 4281 4 fluid fluid NN cord-022526-j9kg00qf 4281 5 and and CC cord-022526-j9kg00qf 4281 6 electrolytes electrolyte NNS cord-022526-j9kg00qf 4281 7 orally orally RB cord-022526-j9kg00qf 4281 8 or or CC cord-022526-j9kg00qf 4281 9 intravenously intravenously RB cord-022526-j9kg00qf 4281 10 . . . cord-022526-j9kg00qf 4282 1 Some some DT cord-022526-j9kg00qf 4282 2 horses horse NNS cord-022526-j9kg00qf 4282 3 with with IN cord-022526-j9kg00qf 4282 4 mild mild JJ cord-022526-j9kg00qf 4282 5 to to IN cord-022526-j9kg00qf 4282 6 moderate moderate JJ cord-022526-j9kg00qf 4282 7 diarrhea diarrhea NN cord-022526-j9kg00qf 4282 8 may may MD cord-022526-j9kg00qf 4282 9 maintain maintain VB cord-022526-j9kg00qf 4282 10 hydration hydration NN cord-022526-j9kg00qf 4282 11 and and CC cord-022526-j9kg00qf 4282 12 electrolyte electrolyte JJ cord-022526-j9kg00qf 4282 13 balance balance NN cord-022526-j9kg00qf 4282 14 by by IN cord-022526-j9kg00qf 4282 15 consuming consume VBG cord-022526-j9kg00qf 4282 16 water water NN cord-022526-j9kg00qf 4282 17 and and CC cord-022526-j9kg00qf 4282 18 electrolytes electrolyte NNS cord-022526-j9kg00qf 4282 19 voluntarily voluntarily RB cord-022526-j9kg00qf 4282 20 . . . cord-022526-j9kg00qf 4283 1 Freshwater freshwater NN cord-022526-j9kg00qf 4283 2 and and CC cord-022526-j9kg00qf 4283 3 water water NN cord-022526-j9kg00qf 4283 4 containing contain VBG cord-022526-j9kg00qf 4283 5 electrolytes electrolyte NNS cord-022526-j9kg00qf 4283 6 should should MD cord-022526-j9kg00qf 4283 7 be be VB cord-022526-j9kg00qf 4283 8 available available JJ cord-022526-j9kg00qf 4283 9 in in IN cord-022526-j9kg00qf 4283 10 all all DT cord-022526-j9kg00qf 4283 11 cases case NNS cord-022526-j9kg00qf 4283 12 . . . cord-022526-j9kg00qf 4284 1 In in IN cord-022526-j9kg00qf 4284 2 many many JJ cord-022526-j9kg00qf 4284 3 instances instance NNS cord-022526-j9kg00qf 4284 4 , , , cord-022526-j9kg00qf 4284 5 periodic periodic JJ cord-022526-j9kg00qf 4284 6 nasogastric nasogastric NN cord-022526-j9kg00qf 4284 7 intubation intubation NN cord-022526-j9kg00qf 4284 8 and and CC cord-022526-j9kg00qf 4284 9 administration administration NN cord-022526-j9kg00qf 4284 10 of of IN cord-022526-j9kg00qf 4284 11 water water NN cord-022526-j9kg00qf 4284 12 and and CC cord-022526-j9kg00qf 4284 13 electrolytes electrolyte NNS cord-022526-j9kg00qf 4284 14 via via IN cord-022526-j9kg00qf 4284 15 the the DT cord-022526-j9kg00qf 4284 16 tube tube NN cord-022526-j9kg00qf 4284 17 may may MD cord-022526-j9kg00qf 4284 18 be be VB cord-022526-j9kg00qf 4284 19 sufficient sufficient JJ cord-022526-j9kg00qf 4284 20 to to TO cord-022526-j9kg00qf 4284 21 maintain maintain VB cord-022526-j9kg00qf 4284 22 hydration hydration NN cord-022526-j9kg00qf 4284 23 . . . cord-022526-j9kg00qf 4285 1 214 214 CD cord-022526-j9kg00qf 4286 1 In in IN cord-022526-j9kg00qf 4286 2 more more JJR cord-022526-j9kg00qf 4286 3 severe severe JJ cord-022526-j9kg00qf 4286 4 cases case NNS cord-022526-j9kg00qf 4286 5 , , , cord-022526-j9kg00qf 4286 6 one one PRP cord-022526-j9kg00qf 4286 7 can can MD cord-022526-j9kg00qf 4286 8 maintain maintain VB cord-022526-j9kg00qf 4286 9 indwelling indwell VBG cord-022526-j9kg00qf 4286 10 nasogastric nasogastric NN cord-022526-j9kg00qf 4286 11 tubes tube NNS cord-022526-j9kg00qf 4286 12 and and CC cord-022526-j9kg00qf 4286 13 can can MD cord-022526-j9kg00qf 4286 14 administer administer VB cord-022526-j9kg00qf 4286 15 up up IN cord-022526-j9kg00qf 4286 16 to to TO cord-022526-j9kg00qf 4286 17 4 4 CD cord-022526-j9kg00qf 4286 18 to to TO cord-022526-j9kg00qf 4286 19 8 8 CD cord-022526-j9kg00qf 4286 20 L l NN cord-022526-j9kg00qf 4286 21 of of IN cord-022526-j9kg00qf 4286 22 fluid fluid NN cord-022526-j9kg00qf 4286 23 by by IN cord-022526-j9kg00qf 4286 24 the the DT cord-022526-j9kg00qf 4286 25 tube tube NN cord-022526-j9kg00qf 4286 26 every every DT cord-022526-j9kg00qf 4286 27 20 20 CD cord-022526-j9kg00qf 4286 28 to to TO cord-022526-j9kg00qf 4286 29 30 30 CD cord-022526-j9kg00qf 4286 30 minutes minute NNS cord-022526-j9kg00qf 4286 31 , , , cord-022526-j9kg00qf 4286 32 if if IN cord-022526-j9kg00qf 4286 33 ileus ileus NNP cord-022526-j9kg00qf 4286 34 is be VBZ cord-022526-j9kg00qf 4286 35 not not RB cord-022526-j9kg00qf 4286 36 evident evident JJ cord-022526-j9kg00qf 4286 37 . . . cord-022526-j9kg00qf 4287 1 However however RB cord-022526-j9kg00qf 4287 2 , , , cord-022526-j9kg00qf 4287 3 intravenous intravenous JJ cord-022526-j9kg00qf 4287 4 administration administration NN cord-022526-j9kg00qf 4287 5 of of IN cord-022526-j9kg00qf 4287 6 fluids fluid NNS cord-022526-j9kg00qf 4287 7 is be VBZ cord-022526-j9kg00qf 4287 8 preferred prefer VBN cord-022526-j9kg00qf 4287 9 in in IN cord-022526-j9kg00qf 4287 10 most most JJS cord-022526-j9kg00qf 4287 11 cases case NNS cord-022526-j9kg00qf 4287 12 , , , cord-022526-j9kg00qf 4287 13 requiring require VBG cord-022526-j9kg00qf 4287 14 significant significant JJ cord-022526-j9kg00qf 4287 15 quantities quantity NNS cord-022526-j9kg00qf 4287 16 of of IN cord-022526-j9kg00qf 4287 17 fluid fluid NN cord-022526-j9kg00qf 4287 18 to to TO cord-022526-j9kg00qf 4287 19 replace replace VB cord-022526-j9kg00qf 4287 20 and and CC cord-022526-j9kg00qf 4287 21 maintain maintain VB cord-022526-j9kg00qf 4287 22 hydration hydration NN cord-022526-j9kg00qf 4287 23 and and CC cord-022526-j9kg00qf 4287 24 electrolyte electrolyte JJ cord-022526-j9kg00qf 4287 25 balance balance NN cord-022526-j9kg00qf 4287 26 . . . cord-022526-j9kg00qf 4288 1 215 215 CD cord-022526-j9kg00qf 4289 1 For for IN cord-022526-j9kg00qf 4289 2 patients patient NNS cord-022526-j9kg00qf 4289 3 with with IN cord-022526-j9kg00qf 4289 4 severe severe JJ cord-022526-j9kg00qf 4289 5 diarrhea diarrhea NN cord-022526-j9kg00qf 4289 6 to to TO cord-022526-j9kg00qf 4289 7 require require VB cord-022526-j9kg00qf 4289 8 large large JJ cord-022526-j9kg00qf 4289 9 volumes volume NNS cord-022526-j9kg00qf 4289 10 ( ( -LRB- cord-022526-j9kg00qf 4289 11 50 50 CD cord-022526-j9kg00qf 4289 12 to to TO cord-022526-j9kg00qf 4289 13 100 100 CD cord-022526-j9kg00qf 4289 14 L l NN cord-022526-j9kg00qf 4289 15 / / SYM cord-022526-j9kg00qf 4289 16 day day NN cord-022526-j9kg00qf 4289 17 ) ) -RRB- cord-022526-j9kg00qf 4289 18 of of IN cord-022526-j9kg00qf 4289 19 intravenous intravenous JJ cord-022526-j9kg00qf 4289 20 fluids fluid NNS cord-022526-j9kg00qf 4289 21 to to TO cord-022526-j9kg00qf 4289 22 maintain maintain VB cord-022526-j9kg00qf 4289 23 hydration hydration NN cord-022526-j9kg00qf 4289 24 is be VBZ cord-022526-j9kg00qf 4289 25 not not RB cord-022526-j9kg00qf 4289 26 unusual unusual JJ cord-022526-j9kg00qf 4289 27 . . . cord-022526-j9kg00qf 4290 1 Frequent frequent JJ cord-022526-j9kg00qf 4290 2 monitoring monitoring NN cord-022526-j9kg00qf 4290 3 of of IN cord-022526-j9kg00qf 4290 4 packed pack VBN cord-022526-j9kg00qf 4290 5 cell cell NN cord-022526-j9kg00qf 4290 6 volume volume NN cord-022526-j9kg00qf 4290 7 , , , cord-022526-j9kg00qf 4290 8 serum serum NN cord-022526-j9kg00qf 4290 9 electrolyte electrolyte NN cord-022526-j9kg00qf 4290 10 concentration concentration NN cord-022526-j9kg00qf 4290 11 , , , cord-022526-j9kg00qf 4290 12 venous venous JJ cord-022526-j9kg00qf 4290 13 blood blood NN cord-022526-j9kg00qf 4290 14 gases gas NNS cord-022526-j9kg00qf 4290 15 or or CC cord-022526-j9kg00qf 4290 16 total total JJ cord-022526-j9kg00qf 4290 17 serum serum NN cord-022526-j9kg00qf 4290 18 carbon carbon NN cord-022526-j9kg00qf 4290 19 dioxide dioxide NN cord-022526-j9kg00qf 4290 20 , , , cord-022526-j9kg00qf 4290 21 blood blood NN cord-022526-j9kg00qf 4290 22 urea urea NN cord-022526-j9kg00qf 4290 23 nitrogen nitrogen NN cord-022526-j9kg00qf 4290 24 and and CC cord-022526-j9kg00qf 4290 25 creatinine creatinine NN cord-022526-j9kg00qf 4290 26 , , , cord-022526-j9kg00qf 4290 27 urine urine NN cord-022526-j9kg00qf 4290 28 protein protein NN cord-022526-j9kg00qf 4290 29 and and CC cord-022526-j9kg00qf 4290 30 cytologic cytologic JJ cord-022526-j9kg00qf 4290 31 findings finding NNS cord-022526-j9kg00qf 4290 32 , , , cord-022526-j9kg00qf 4290 33 and and CC cord-022526-j9kg00qf 4290 34 body body NN cord-022526-j9kg00qf 4290 35 weight weight NN cord-022526-j9kg00qf 4290 36 is be VBZ cord-022526-j9kg00qf 4290 37 important important JJ cord-022526-j9kg00qf 4290 38 to to TO cord-022526-j9kg00qf 4290 39 monitor monitor VB cord-022526-j9kg00qf 4290 40 hydration hydration NN cord-022526-j9kg00qf 4290 41 , , , cord-022526-j9kg00qf 4290 42 electrolyte electrolyte NN cord-022526-j9kg00qf 4290 43 and and CC cord-022526-j9kg00qf 4290 44 acid acid NN cord-022526-j9kg00qf 4290 45 - - HYPH cord-022526-j9kg00qf 4290 46 base base NN cord-022526-j9kg00qf 4290 47 balance balance NN cord-022526-j9kg00qf 4290 48 , , , cord-022526-j9kg00qf 4290 49 and and CC cord-022526-j9kg00qf 4290 50 renal renal JJ cord-022526-j9kg00qf 4290 51 function function NN cord-022526-j9kg00qf 4290 52 . . . cord-022526-j9kg00qf 4291 1 Isotonic isotonic JJ cord-022526-j9kg00qf 4291 2 sodium sodium NN cord-022526-j9kg00qf 4291 3 chloride chloride NN cord-022526-j9kg00qf 4291 4 or or CC cord-022526-j9kg00qf 4291 5 lactated lactate VBD cord-022526-j9kg00qf 4291 6 Ringer Ringer NNP cord-022526-j9kg00qf 4291 7 's 's POS cord-022526-j9kg00qf 4291 8 solution solution NN cord-022526-j9kg00qf 4291 9 frequently frequently RB cord-022526-j9kg00qf 4291 10 is be VBZ cord-022526-j9kg00qf 4291 11 used use VBN cord-022526-j9kg00qf 4291 12 to to TO cord-022526-j9kg00qf 4291 13 restore restore VB cord-022526-j9kg00qf 4291 14 and and CC cord-022526-j9kg00qf 4291 15 maintain maintain VB cord-022526-j9kg00qf 4291 16 fluid fluid JJ cord-022526-j9kg00qf 4291 17 and and CC cord-022526-j9kg00qf 4291 18 electrolyte electrolyte JJ cord-022526-j9kg00qf 4291 19 balance balance NN cord-022526-j9kg00qf 4291 20 . . . cord-022526-j9kg00qf 4292 1 One one PRP cord-022526-j9kg00qf 4292 2 can can MD cord-022526-j9kg00qf 4292 3 add add VB cord-022526-j9kg00qf 4292 4 potassium potassium NN cord-022526-j9kg00qf 4292 5 chloride chloride NN cord-022526-j9kg00qf 4292 6 to to IN cord-022526-j9kg00qf 4292 7 the the DT cord-022526-j9kg00qf 4292 8 fluids fluid NNS cord-022526-j9kg00qf 4292 9 and and CC cord-022526-j9kg00qf 4292 10 administer administer VB cord-022526-j9kg00qf 4292 11 it -PRON- PRP cord-022526-j9kg00qf 4292 12 at at IN cord-022526-j9kg00qf 4292 13 a a DT cord-022526-j9kg00qf 4292 14 rate rate NN cord-022526-j9kg00qf 4292 15 up up IN cord-022526-j9kg00qf 4292 16 to to IN cord-022526-j9kg00qf 4292 17 0.5 0.5 CD cord-022526-j9kg00qf 4292 18 to to TO cord-022526-j9kg00qf 4292 19 1.0 1.0 CD cord-022526-j9kg00qf 4292 20 mEq/ mEq/ NNP cord-022526-j9kg00qf 4292 21 kg kg NNP cord-022526-j9kg00qf 4292 22 / / SYM cord-022526-j9kg00qf 4292 23 hr hr NN cord-022526-j9kg00qf 4292 24 . . . cord-022526-j9kg00qf 4293 1 Generally generally RB cord-022526-j9kg00qf 4293 2 , , , cord-022526-j9kg00qf 4293 3 a a DT cord-022526-j9kg00qf 4293 4 rate rate NN cord-022526-j9kg00qf 4293 5 of of IN cord-022526-j9kg00qf 4293 6 less less JJR cord-022526-j9kg00qf 4293 7 than than IN cord-022526-j9kg00qf 4293 8 0.5 0.5 CD cord-022526-j9kg00qf 4293 9 mEq mEq NNS cord-022526-j9kg00qf 4293 10 / / SYM cord-022526-j9kg00qf 4293 11 kg kg NNP cord-022526-j9kg00qf 4293 12 / / SYM cord-022526-j9kg00qf 4293 13 hr hr NNP cord-022526-j9kg00qf 4293 14 is be VBZ cord-022526-j9kg00qf 4293 15 used use VBN cord-022526-j9kg00qf 4293 16 . . . cord-022526-j9kg00qf 4294 1 Hypertonic Hypertonic NNP cord-022526-j9kg00qf 4294 2 NaCl NaCl NNP cord-022526-j9kg00qf 4294 3 solutions solution NNS cord-022526-j9kg00qf 4294 4 ( ( -LRB- cord-022526-j9kg00qf 4294 5 1 1 CD cord-022526-j9kg00qf 4294 6 to to IN cord-022526-j9kg00qf 4294 7 2 2 CD cord-022526-j9kg00qf 4294 8 L l NN cord-022526-j9kg00qf 4294 9 of of IN cord-022526-j9kg00qf 4294 10 3 3 CD cord-022526-j9kg00qf 4294 11 % % NN cord-022526-j9kg00qf 4294 12 to to TO cord-022526-j9kg00qf 4294 13 5 5 CD cord-022526-j9kg00qf 4294 14 % % NN cord-022526-j9kg00qf 4294 15 NaCl nacl NN cord-022526-j9kg00qf 4294 16 ) ) -RRB- cord-022526-j9kg00qf 4294 17 have have VBP cord-022526-j9kg00qf 4294 18 been be VBN cord-022526-j9kg00qf 4294 19 used use VBN cord-022526-j9kg00qf 4294 20 in in IN cord-022526-j9kg00qf 4294 21 horses horse NNS cord-022526-j9kg00qf 4294 22 that that WDT cord-022526-j9kg00qf 4294 23 are be VBP cord-022526-j9kg00qf 4294 24 severely severely RB cord-022526-j9kg00qf 4294 25 hyponatremic hyponatremic JJ cord-022526-j9kg00qf 4294 26 ( ( -LRB- cord-022526-j9kg00qf 4294 27 < < XX cord-022526-j9kg00qf 4294 28 120 120 CD cord-022526-j9kg00qf 4294 29 mEq mEq NNS cord-022526-j9kg00qf 4294 30 / / SYM cord-022526-j9kg00qf 4294 31 dl dl NNP cord-022526-j9kg00qf 4294 32 ) ) -RRB- cord-022526-j9kg00qf 4294 33 . . . cord-022526-j9kg00qf 4295 1 One one PRP cord-022526-j9kg00qf 4295 2 should should MD cord-022526-j9kg00qf 4295 3 not not RB cord-022526-j9kg00qf 4295 4 administer administer VB cord-022526-j9kg00qf 4295 5 hypertonic hypertonic JJ cord-022526-j9kg00qf 4295 6 solutions solution NNS cord-022526-j9kg00qf 4295 7 to to IN cord-022526-j9kg00qf 4295 8 severely severely RB cord-022526-j9kg00qf 4295 9 dehydrated dehydrated JJ cord-022526-j9kg00qf 4295 10 horses horse NNS cord-022526-j9kg00qf 4295 11 , , , cord-022526-j9kg00qf 4295 12 but but CC cord-022526-j9kg00qf 4295 13 such such JJ cord-022526-j9kg00qf 4295 14 solutions solution NNS cord-022526-j9kg00qf 4295 15 have have VBP cord-022526-j9kg00qf 4295 16 been be VBN cord-022526-j9kg00qf 4295 17 used use VBN cord-022526-j9kg00qf 4295 18 clinically clinically RB cord-022526-j9kg00qf 4295 19 without without IN cord-022526-j9kg00qf 4295 20 complication complication NN cord-022526-j9kg00qf 4295 21 and and CC cord-022526-j9kg00qf 4295 22 with with IN cord-022526-j9kg00qf 4295 23 considerable considerable JJ cord-022526-j9kg00qf 4295 24 beneficial beneficial JJ cord-022526-j9kg00qf 4295 25 effect effect NN cord-022526-j9kg00qf 4295 26 in in IN cord-022526-j9kg00qf 4295 27 patients patient NNS cord-022526-j9kg00qf 4295 28 with with IN cord-022526-j9kg00qf 4295 29 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4295 30 . . . cord-022526-j9kg00qf 4296 1 The the DT cord-022526-j9kg00qf 4296 2 beneficial beneficial JJ cord-022526-j9kg00qf 4296 3 effects effect NNS cord-022526-j9kg00qf 4296 4 of of IN cord-022526-j9kg00qf 4296 5 hypertonic hypertonic JJ cord-022526-j9kg00qf 4296 6 NaCl nacl NN cord-022526-j9kg00qf 4296 7 are be VBP cord-022526-j9kg00qf 4296 8 short short RB cord-022526-j9kg00qf 4296 9 - - HYPH cord-022526-j9kg00qf 4296 10 lived live VBN cord-022526-j9kg00qf 4296 11 ( ( -LRB- cord-022526-j9kg00qf 4296 12 30 30 CD cord-022526-j9kg00qf 4296 13 to to TO cord-022526-j9kg00qf 4296 14 60 60 CD cord-022526-j9kg00qf 4296 15 minutes minute NNS cord-022526-j9kg00qf 4296 16 ) ) -RRB- cord-022526-j9kg00qf 4296 17 . . . cord-022526-j9kg00qf 4297 1 One one PRP cord-022526-j9kg00qf 4297 2 should should MD cord-022526-j9kg00qf 4297 3 administer administer VB cord-022526-j9kg00qf 4297 4 isotonic isotonic JJ cord-022526-j9kg00qf 4297 5 solutions solution NNS cord-022526-j9kg00qf 4297 6 concurrently concurrently RB cord-022526-j9kg00qf 4297 7 or or CC cord-022526-j9kg00qf 4297 8 immediately immediately RB cord-022526-j9kg00qf 4297 9 following follow VBG cord-022526-j9kg00qf 4297 10 administration administration NN cord-022526-j9kg00qf 4297 11 of of IN cord-022526-j9kg00qf 4297 12 hypertonic hypertonic JJ cord-022526-j9kg00qf 4297 13 NaCl NaCl NNP cord-022526-j9kg00qf 4297 14 solutions solution NNS cord-022526-j9kg00qf 4297 15 . . . cord-022526-j9kg00qf 4298 1 Isotonic isotonic JJ cord-022526-j9kg00qf 4298 2 ( ( -LRB- cord-022526-j9kg00qf 4298 3 1.3 1.3 CD cord-022526-j9kg00qf 4298 4 % % NN cord-022526-j9kg00qf 4298 5 ) ) -RRB- cord-022526-j9kg00qf 4298 6 or or CC cord-022526-j9kg00qf 4298 7 hypertonic hypertonic JJ cord-022526-j9kg00qf 4298 8 ( ( -LRB- cord-022526-j9kg00qf 4298 9 5.0 5.0 CD cord-022526-j9kg00qf 4298 10 % % NN cord-022526-j9kg00qf 4298 11 ) ) -RRB- cord-022526-j9kg00qf 4298 12 sodium sodium NN cord-022526-j9kg00qf 4298 13 bicarbonate bicarbonate NN cord-022526-j9kg00qf 4298 14 solutions solution NNS cord-022526-j9kg00qf 4298 15 are be VBP cord-022526-j9kg00qf 4298 16 used use VBN cord-022526-j9kg00qf 4298 17 to to TO cord-022526-j9kg00qf 4298 18 correct correct VB cord-022526-j9kg00qf 4298 19 metabolic metabolic JJ cord-022526-j9kg00qf 4298 20 acidosis acidosis NN cord-022526-j9kg00qf 4298 21 . . . cord-022526-j9kg00qf 4299 1 Prolonged prolonged JJ cord-022526-j9kg00qf 4299 2 administration administration NN cord-022526-j9kg00qf 4299 3 of of IN cord-022526-j9kg00qf 4299 4 sodium sodium NN cord-022526-j9kg00qf 4299 5 - - HYPH cord-022526-j9kg00qf 4299 6 containing contain VBG cord-022526-j9kg00qf 4299 7 fluids fluid NNS cord-022526-j9kg00qf 4299 8 may may MD cord-022526-j9kg00qf 4299 9 promote promote VB cord-022526-j9kg00qf 4299 10 diuresis diuresis NN cord-022526-j9kg00qf 4299 11 and and CC cord-022526-j9kg00qf 4299 12 renal renal JJ cord-022526-j9kg00qf 4299 13 water water NN cord-022526-j9kg00qf 4299 14 loss loss NN cord-022526-j9kg00qf 4299 15 or or CC cord-022526-j9kg00qf 4299 16 accumulation accumulation NN cord-022526-j9kg00qf 4299 17 of of IN cord-022526-j9kg00qf 4299 18 peripheral peripheral JJ cord-022526-j9kg00qf 4299 19 edema edema NN cord-022526-j9kg00qf 4299 20 and and CC cord-022526-j9kg00qf 4299 21 should should MD cord-022526-j9kg00qf 4299 22 be be VB cord-022526-j9kg00qf 4299 23 used use VBN cord-022526-j9kg00qf 4299 24 conservatively conservatively RB cord-022526-j9kg00qf 4299 25 when when WRB cord-022526-j9kg00qf 4299 26 one one CD cord-022526-j9kg00qf 4299 27 notes note VBZ cord-022526-j9kg00qf 4299 28 a a DT cord-022526-j9kg00qf 4299 29 free free JJ cord-022526-j9kg00qf 4299 30 water water NN cord-022526-j9kg00qf 4299 31 loss loss NN cord-022526-j9kg00qf 4299 32 . . . cord-022526-j9kg00qf 4300 1 Administration administration NN cord-022526-j9kg00qf 4300 2 of of IN cord-022526-j9kg00qf 4300 3 isotonic isotonic JJ cord-022526-j9kg00qf 4300 4 dextrose dextrose NN cord-022526-j9kg00qf 4300 5 ( ( -LRB- cord-022526-j9kg00qf 4300 6 5 5 CD cord-022526-j9kg00qf 4300 7 % % NN cord-022526-j9kg00qf 4300 8 ) ) -RRB- cord-022526-j9kg00qf 4300 9 or or CC cord-022526-j9kg00qf 4300 10 2.5 2.5 CD cord-022526-j9kg00qf 4300 11 % % NN cord-022526-j9kg00qf 4300 12 dextrose/0.45 dextrose/0.45 CD cord-022526-j9kg00qf 4300 13 % % NN cord-022526-j9kg00qf 4300 14 NaCl nacl NN cord-022526-j9kg00qf 4300 15 solutions solution NNS cord-022526-j9kg00qf 4300 16 may may MD cord-022526-j9kg00qf 4300 17 be be VB cord-022526-j9kg00qf 4300 18 beneficial beneficial JJ cord-022526-j9kg00qf 4300 19 when when WRB cord-022526-j9kg00qf 4300 20 free free JJ cord-022526-j9kg00qf 4300 21 water water NN cord-022526-j9kg00qf 4300 22 loss loss NN cord-022526-j9kg00qf 4300 23 ( ( -LRB- cord-022526-j9kg00qf 4300 24 sodium sodium NN cord-022526-j9kg00qf 4300 25 excess excess NN cord-022526-j9kg00qf 4300 26 ) ) -RRB- cord-022526-j9kg00qf 4300 27 is be VBZ cord-022526-j9kg00qf 4300 28 evident evident JJ cord-022526-j9kg00qf 4300 29 . . . cord-022526-j9kg00qf 4301 1 Many many JJ cord-022526-j9kg00qf 4301 2 horses horse NNS cord-022526-j9kg00qf 4301 3 with with IN cord-022526-j9kg00qf 4301 4 acute acute JJ cord-022526-j9kg00qf 4301 5 colitis colitis NN cord-022526-j9kg00qf 4301 6 are be VBP cord-022526-j9kg00qf 4301 7 concurrently concurrently RB cord-022526-j9kg00qf 4301 8 hypoproteinemic hypoproteinemic JJ cord-022526-j9kg00qf 4301 9 because because IN cord-022526-j9kg00qf 4301 10 of of IN cord-022526-j9kg00qf 4301 11 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4301 12 losses loss NNS cord-022526-j9kg00qf 4301 13 and and CC cord-022526-j9kg00qf 4301 14 are be VBP cord-022526-j9kg00qf 4301 15 absorbing absorb VBG cord-022526-j9kg00qf 4301 16 bacterial bacterial JJ cord-022526-j9kg00qf 4301 17 products product NNS cord-022526-j9kg00qf 4301 18 that that WDT cord-022526-j9kg00qf 4301 19 induce induce VBP cord-022526-j9kg00qf 4301 20 a a DT cord-022526-j9kg00qf 4301 21 systemic systemic JJ cord-022526-j9kg00qf 4301 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 4301 23 response response NN cord-022526-j9kg00qf 4301 24 . . . cord-022526-j9kg00qf 4302 1 Thus thus RB cord-022526-j9kg00qf 4302 2 plasma plasma NN cord-022526-j9kg00qf 4302 3 oncotic oncotic JJ cord-022526-j9kg00qf 4302 4 pressures pressure NNS cord-022526-j9kg00qf 4302 5 are be VBP cord-022526-j9kg00qf 4302 6 abnormally abnormally RB cord-022526-j9kg00qf 4302 7 low low JJ cord-022526-j9kg00qf 4302 8 in in IN cord-022526-j9kg00qf 4302 9 the the DT cord-022526-j9kg00qf 4302 10 face face NN cord-022526-j9kg00qf 4302 11 of of IN cord-022526-j9kg00qf 4302 12 increased increase VBN cord-022526-j9kg00qf 4302 13 vascular vascular JJ cord-022526-j9kg00qf 4302 14 permeability permeability NN cord-022526-j9kg00qf 4302 15 . . . cord-022526-j9kg00qf 4303 1 Interstitial interstitial JJ cord-022526-j9kg00qf 4303 2 edema edema NN cord-022526-j9kg00qf 4303 3 formation formation NN cord-022526-j9kg00qf 4303 4 is be VBZ cord-022526-j9kg00qf 4303 5 a a DT cord-022526-j9kg00qf 4303 6 clinical clinical JJ cord-022526-j9kg00qf 4303 7 problem problem NN cord-022526-j9kg00qf 4303 8 in in IN cord-022526-j9kg00qf 4303 9 these these DT cord-022526-j9kg00qf 4303 10 patients patient NNS cord-022526-j9kg00qf 4303 11 and and CC cord-022526-j9kg00qf 4303 12 contributes contribute VBZ cord-022526-j9kg00qf 4303 13 to to IN cord-022526-j9kg00qf 4303 14 organ organ NN cord-022526-j9kg00qf 4303 15 dysfunction dysfunction NN cord-022526-j9kg00qf 4303 16 . . . cord-022526-j9kg00qf 4304 1 Crystalloid crystalloid NN cord-022526-j9kg00qf 4304 2 fluids fluid NNS cord-022526-j9kg00qf 4304 3 , , , cord-022526-j9kg00qf 4304 4 although although IN cord-022526-j9kg00qf 4304 5 critical critical JJ cord-022526-j9kg00qf 4304 6 for for IN cord-022526-j9kg00qf 4304 7 replacing replace VBG cord-022526-j9kg00qf 4304 8 water water NN cord-022526-j9kg00qf 4304 9 and and CC cord-022526-j9kg00qf 4304 10 electrolyte electrolyte JJ cord-022526-j9kg00qf 4304 11 losses loss NNS cord-022526-j9kg00qf 4304 12 from from IN cord-022526-j9kg00qf 4304 13 diarrhea diarrhea NN cord-022526-j9kg00qf 4304 14 , , , cord-022526-j9kg00qf 4304 15 actually actually RB cord-022526-j9kg00qf 4304 16 may may MD cord-022526-j9kg00qf 4304 17 contribute contribute VB cord-022526-j9kg00qf 4304 18 to to IN cord-022526-j9kg00qf 4304 19 a a DT cord-022526-j9kg00qf 4304 20 drop drop NN cord-022526-j9kg00qf 4304 21 in in IN cord-022526-j9kg00qf 4304 22 plasma plasma NN cord-022526-j9kg00qf 4304 23 oncotic oncotic JJ cord-022526-j9kg00qf 4304 24 pressure pressure NN cord-022526-j9kg00qf 4304 25 because because IN cord-022526-j9kg00qf 4304 26 of of IN cord-022526-j9kg00qf 4304 27 hemodilution hemodilution NN cord-022526-j9kg00qf 4304 28 . . . cord-022526-j9kg00qf 4305 1 216 216 CD cord-022526-j9kg00qf 4305 2 , , , cord-022526-j9kg00qf 4305 3 217 217 CD cord-022526-j9kg00qf 4305 4 Administration Administration NNP cord-022526-j9kg00qf 4305 5 of of IN cord-022526-j9kg00qf 4305 6 colloid colloid NN cord-022526-j9kg00qf 4305 7 solutions solution NNS cord-022526-j9kg00qf 4305 8 are be VBP cord-022526-j9kg00qf 4305 9 important important JJ cord-022526-j9kg00qf 4305 10 for for IN cord-022526-j9kg00qf 4305 11 volume volume NN cord-022526-j9kg00qf 4305 12 expansion expansion NN cord-022526-j9kg00qf 4305 13 and and CC cord-022526-j9kg00qf 4305 14 to to TO cord-022526-j9kg00qf 4305 15 maintain maintain VB cord-022526-j9kg00qf 4305 16 plasma plasma NN cord-022526-j9kg00qf 4305 17 oncotic oncotic JJ cord-022526-j9kg00qf 4305 18 pressures pressure NNS cord-022526-j9kg00qf 4305 19 , , , cord-022526-j9kg00qf 4305 20 which which WDT cord-022526-j9kg00qf 4305 21 improve improve VBP cord-022526-j9kg00qf 4305 22 tissue tissue NN cord-022526-j9kg00qf 4305 23 perfusion perfusion NN cord-022526-j9kg00qf 4305 24 and and CC cord-022526-j9kg00qf 4305 25 oxygenation oxygenation NN cord-022526-j9kg00qf 4305 26 and and CC cord-022526-j9kg00qf 4305 27 organ organ NN cord-022526-j9kg00qf 4305 28 function function NN cord-022526-j9kg00qf 4305 29 in in IN cord-022526-j9kg00qf 4305 30 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 4305 31 , , , cord-022526-j9kg00qf 4305 32 hypotensive hypotensive JJ cord-022526-j9kg00qf 4305 33 , , , cord-022526-j9kg00qf 4305 34 and and CC cord-022526-j9kg00qf 4305 35 hypoproteinemic hypoproteinemic NN cord-022526-j9kg00qf 4305 36 patients patient NNS cord-022526-j9kg00qf 4305 37 with with IN cord-022526-j9kg00qf 4305 38 or or CC cord-022526-j9kg00qf 4305 39 without without IN cord-022526-j9kg00qf 4305 40 systemic systemic JJ cord-022526-j9kg00qf 4305 41 inflammatory inflammatory JJ cord-022526-j9kg00qf 4305 42 response response NN cord-022526-j9kg00qf 4305 43 syndrome syndrome NN cord-022526-j9kg00qf 4305 44 . . . cord-022526-j9kg00qf 4306 1 218 218 CD cord-022526-j9kg00qf 4306 2 Colloids colloid NNS cord-022526-j9kg00qf 4306 3 are be VBP cord-022526-j9kg00qf 4306 4 more more RBR cord-022526-j9kg00qf 4306 5 effective effective JJ cord-022526-j9kg00qf 4306 6 than than IN cord-022526-j9kg00qf 4306 7 crystalloid crystalloid JJ cord-022526-j9kg00qf 4306 8 fluids fluid NNS cord-022526-j9kg00qf 4306 9 at at IN cord-022526-j9kg00qf 4306 10 expanding expand VBG cord-022526-j9kg00qf 4306 11 plasma plasma NN cord-022526-j9kg00qf 4306 12 volume volume NN cord-022526-j9kg00qf 4306 13 and and CC cord-022526-j9kg00qf 4306 14 thus thus RB cord-022526-j9kg00qf 4306 15 require require VBP cord-022526-j9kg00qf 4306 16 smaller small JJR cord-022526-j9kg00qf 4306 17 volumes volume NNS cord-022526-j9kg00qf 4306 18 . . . cord-022526-j9kg00qf 4307 1 Moreover moreover RB cord-022526-j9kg00qf 4307 2 , , , cord-022526-j9kg00qf 4307 3 the the DT cord-022526-j9kg00qf 4307 4 effect effect NN cord-022526-j9kg00qf 4307 5 of of IN cord-022526-j9kg00qf 4307 6 colloid colloid NN cord-022526-j9kg00qf 4307 7 volume volume NN cord-022526-j9kg00qf 4307 8 expansion expansion NN cord-022526-j9kg00qf 4307 9 is be VBZ cord-022526-j9kg00qf 4307 10 longer long RBR cord-022526-j9kg00qf 4307 11 lasting last VBG cord-022526-j9kg00qf 4307 12 than than IN cord-022526-j9kg00qf 4307 13 crystalloid crystalloid JJ cord-022526-j9kg00qf 4307 14 fluid fluid JJ cord-022526-j9kg00qf 4307 15 volume volume NN cord-022526-j9kg00qf 4307 16 expansion expansion NN cord-022526-j9kg00qf 4307 17 , , , cord-022526-j9kg00qf 4307 18 because because IN cord-022526-j9kg00qf 4307 19 colloids colloid NNS cord-022526-j9kg00qf 4307 20 are be VBP cord-022526-j9kg00qf 4307 21 retained retain VBN cord-022526-j9kg00qf 4307 22 in in IN cord-022526-j9kg00qf 4307 23 the the DT cord-022526-j9kg00qf 4307 24 vasculature vasculature NN cord-022526-j9kg00qf 4307 25 better well RBR cord-022526-j9kg00qf 4307 26 . . . cord-022526-j9kg00qf 4308 1 217 217 CD cord-022526-j9kg00qf 4308 2 , , , cord-022526-j9kg00qf 4308 3 218 218 CD cord-022526-j9kg00qf 4308 4 Natural natural JJ cord-022526-j9kg00qf 4308 5 colloids colloid NNS cord-022526-j9kg00qf 4308 6 , , , cord-022526-j9kg00qf 4308 7 such such JJ cord-022526-j9kg00qf 4308 8 as as IN cord-022526-j9kg00qf 4308 9 plasma plasma NN cord-022526-j9kg00qf 4308 10 and and CC cord-022526-j9kg00qf 4308 11 purified purified JJ cord-022526-j9kg00qf 4308 12 albumin albumin NN cord-022526-j9kg00qf 4308 13 are be VBP cord-022526-j9kg00qf 4308 14 used use VBN cord-022526-j9kg00qf 4308 15 commonly commonly RB cord-022526-j9kg00qf 4308 16 . . . cord-022526-j9kg00qf 4309 1 In in IN cord-022526-j9kg00qf 4309 2 addition addition NN cord-022526-j9kg00qf 4309 3 to to IN cord-022526-j9kg00qf 4309 4 its -PRON- PRP$ cord-022526-j9kg00qf 4309 5 beneficial beneficial JJ cord-022526-j9kg00qf 4309 6 colloidal colloidal NN cord-022526-j9kg00qf 4309 7 properties property NNS cord-022526-j9kg00qf 4309 8 , , , cord-022526-j9kg00qf 4309 9 plasma plasma NN cord-022526-j9kg00qf 4309 10 harvested harvest VBN cord-022526-j9kg00qf 4309 11 from from IN cord-022526-j9kg00qf 4309 12 donor donor NN cord-022526-j9kg00qf 4309 13 horses horse NNS cord-022526-j9kg00qf 4309 14 immunized immunize VBN cord-022526-j9kg00qf 4309 15 with with IN cord-022526-j9kg00qf 4309 16 rough rough JJ cord-022526-j9kg00qf 4309 17 mutants mutant NNS cord-022526-j9kg00qf 4309 18 of of IN cord-022526-j9kg00qf 4309 19 Escherichia Escherichia NNP cord-022526-j9kg00qf 4309 20 coli coli NNS cord-022526-j9kg00qf 4309 21 ( ( -LRB- cord-022526-j9kg00qf 4309 22 J5 J5 NNP cord-022526-j9kg00qf 4309 23 ) ) -RRB- cord-022526-j9kg00qf 4309 24 or or CC cord-022526-j9kg00qf 4309 25 Salmonella Salmonella NNP cord-022526-j9kg00qf 4309 26 typhimurium typhimurium NN cord-022526-j9kg00qf 4309 27 may may MD cord-022526-j9kg00qf 4309 28 have have VB cord-022526-j9kg00qf 4309 29 other other JJ cord-022526-j9kg00qf 4309 30 benefits benefit NNS cord-022526-j9kg00qf 4309 31 for for IN cord-022526-j9kg00qf 4309 32 treatment treatment NN cord-022526-j9kg00qf 4309 33 of of IN cord-022526-j9kg00qf 4309 34 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4309 35 from from IN cord-022526-j9kg00qf 4309 36 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4309 37 disease disease NN cord-022526-j9kg00qf 4309 38 . . . cord-022526-j9kg00qf 4310 1 219 219 CD cord-022526-j9kg00qf 4310 2 , , , cord-022526-j9kg00qf 4310 3 220 220 CD cord-022526-j9kg00qf 4311 1 The the DT cord-022526-j9kg00qf 4311 2 horse horse NN cord-022526-j9kg00qf 4311 3 may may MD cord-022526-j9kg00qf 4311 4 require require VB cord-022526-j9kg00qf 4311 5 large large JJ cord-022526-j9kg00qf 4311 6 volumes volume NNS cord-022526-j9kg00qf 4311 7 ( ( -LRB- cord-022526-j9kg00qf 4311 8 6 6 CD cord-022526-j9kg00qf 4311 9 to to TO cord-022526-j9kg00qf 4311 10 8 8 CD cord-022526-j9kg00qf 4311 11 L l NN cord-022526-j9kg00qf 4311 12 / / SYM cord-022526-j9kg00qf 4311 13 day day NN cord-022526-j9kg00qf 4311 14 ) ) -RRB- cord-022526-j9kg00qf 4311 15 to to TO cord-022526-j9kg00qf 4311 16 increase increase VB cord-022526-j9kg00qf 4311 17 and and CC cord-022526-j9kg00qf 4311 18 maintain maintain VB cord-022526-j9kg00qf 4311 19 plasma plasma NN cord-022526-j9kg00qf 4311 20 protein protein NN cord-022526-j9kg00qf 4311 21 concentration concentration NN cord-022526-j9kg00qf 4311 22 significantly significantly RB cord-022526-j9kg00qf 4311 23 . . . cord-022526-j9kg00qf 4312 1 Synthetic synthetic JJ cord-022526-j9kg00qf 4312 2 colloids colloid NNS cord-022526-j9kg00qf 4312 3 such such JJ cord-022526-j9kg00qf 4312 4 as as IN cord-022526-j9kg00qf 4312 5 dextrans dextran NNS cord-022526-j9kg00qf 4312 6 , , , cord-022526-j9kg00qf 4312 7 starches starch NNS cord-022526-j9kg00qf 4312 8 , , , cord-022526-j9kg00qf 4312 9 or or CC cord-022526-j9kg00qf 4312 10 polymerized polymerize VBN cord-022526-j9kg00qf 4312 11 hemoglobin hemoglobin NN cord-022526-j9kg00qf 4312 12 are be VBP cord-022526-j9kg00qf 4312 13 also also RB cord-022526-j9kg00qf 4312 14 available available JJ cord-022526-j9kg00qf 4312 15 for for IN cord-022526-j9kg00qf 4312 16 use use NN cord-022526-j9kg00qf 4312 17 in in IN cord-022526-j9kg00qf 4312 18 the the DT cord-022526-j9kg00qf 4312 19 horse horse NN cord-022526-j9kg00qf 4312 20 . . . cord-022526-j9kg00qf 4313 1 Hetastarch Hetastarch NNP cord-022526-j9kg00qf 4313 2 ( ( -LRB- cord-022526-j9kg00qf 4313 3 5 5 CD cord-022526-j9kg00qf 4313 4 to to TO cord-022526-j9kg00qf 4313 5 10 10 CD cord-022526-j9kg00qf 4313 6 ml ml NNS cord-022526-j9kg00qf 4313 7 / / SYM cord-022526-j9kg00qf 4313 8 kg kg NNS cord-022526-j9kg00qf 4313 9 of of IN cord-022526-j9kg00qf 4313 10 a a DT cord-022526-j9kg00qf 4313 11 6 6 CD cord-022526-j9kg00qf 4313 12 % % NN cord-022526-j9kg00qf 4313 13 solution solution NN cord-022526-j9kg00qf 4313 14 ) ) -RRB- cord-022526-j9kg00qf 4313 15 increases increase VBZ cord-022526-j9kg00qf 4313 16 colloidal colloidal NN cord-022526-j9kg00qf 4313 17 oncotic oncotic JJ cord-022526-j9kg00qf 4313 18 pressures pressure NNS cord-022526-j9kg00qf 4313 19 for for IN cord-022526-j9kg00qf 4313 20 up up IN cord-022526-j9kg00qf 4313 21 to to TO cord-022526-j9kg00qf 4313 22 24 24 CD cord-022526-j9kg00qf 4313 23 hours hour NNS cord-022526-j9kg00qf 4313 24 in in IN cord-022526-j9kg00qf 4313 25 hypoproteinemic hypoproteinemic JJ cord-022526-j9kg00qf 4313 26 horses horse NNS cord-022526-j9kg00qf 4313 27 and and CC cord-022526-j9kg00qf 4313 28 has have VBZ cord-022526-j9kg00qf 4313 29 beneficial beneficial JJ cord-022526-j9kg00qf 4313 30 effects effect NNS cord-022526-j9kg00qf 4313 31 on on IN cord-022526-j9kg00qf 4313 32 cardiac cardiac JJ cord-022526-j9kg00qf 4313 33 output output NN cord-022526-j9kg00qf 4313 34 and and CC cord-022526-j9kg00qf 4313 35 other other JJ cord-022526-j9kg00qf 4313 36 cardiorespiratory cardiorespiratory JJ cord-022526-j9kg00qf 4313 37 parameters parameter NNS cord-022526-j9kg00qf 4313 38 , , , cord-022526-j9kg00qf 4313 39 vascular vascular JJ cord-022526-j9kg00qf 4313 40 permeability permeability NN cord-022526-j9kg00qf 4313 41 , , , cord-022526-j9kg00qf 4313 42 interstitial interstitial JJ cord-022526-j9kg00qf 4313 43 fluid fluid NN cord-022526-j9kg00qf 4313 44 content content NN cord-022526-j9kg00qf 4313 45 , , , cord-022526-j9kg00qf 4313 46 and and CC cord-022526-j9kg00qf 4313 47 tissue tissue NN cord-022526-j9kg00qf 4313 48 perfusion perfusion NN cord-022526-j9kg00qf 4313 49 in in IN cord-022526-j9kg00qf 4313 50 models model NNS cord-022526-j9kg00qf 4313 51 of of IN cord-022526-j9kg00qf 4313 52 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 4313 53 and and CC cord-022526-j9kg00qf 4313 54 systemic systemic JJ cord-022526-j9kg00qf 4313 55 inflammatory inflammatory JJ cord-022526-j9kg00qf 4313 56 response response NN cord-022526-j9kg00qf 4313 57 syndrome syndrome NN cord-022526-j9kg00qf 4313 58 . . . cord-022526-j9kg00qf 4314 1 When when WRB cord-022526-j9kg00qf 4314 2 one one PRP cord-022526-j9kg00qf 4314 3 administers administer VBZ cord-022526-j9kg00qf 4314 4 synthetic synthetic JJ cord-022526-j9kg00qf 4314 5 or or CC cord-022526-j9kg00qf 4314 6 even even RB cord-022526-j9kg00qf 4314 7 natural natural JJ cord-022526-j9kg00qf 4314 8 colloids colloid NNS cord-022526-j9kg00qf 4314 9 , , , cord-022526-j9kg00qf 4314 10 monitoring monitor VBG cord-022526-j9kg00qf 4314 11 plasma plasma NN cord-022526-j9kg00qf 4314 12 oncotic oncotic JJ cord-022526-j9kg00qf 4314 13 pressure pressure NN cord-022526-j9kg00qf 4314 14 may may MD cord-022526-j9kg00qf 4314 15 be be VB cord-022526-j9kg00qf 4314 16 more more RBR cord-022526-j9kg00qf 4314 17 relevant relevant JJ cord-022526-j9kg00qf 4314 18 than than IN cord-022526-j9kg00qf 4314 19 monitoring monitor VBG cord-022526-j9kg00qf 4314 20 plasma plasma NN cord-022526-j9kg00qf 4314 21 protein protein NN cord-022526-j9kg00qf 4314 22 concentrations concentration NNS cord-022526-j9kg00qf 4314 23 as as IN cord-022526-j9kg00qf 4314 24 a a DT cord-022526-j9kg00qf 4314 25 means means NN cord-022526-j9kg00qf 4314 26 of of IN cord-022526-j9kg00qf 4314 27 assessing assess VBG cord-022526-j9kg00qf 4314 28 the the DT cord-022526-j9kg00qf 4314 29 need need NN cord-022526-j9kg00qf 4314 30 for for IN cord-022526-j9kg00qf 4314 31 plasma plasma NN cord-022526-j9kg00qf 4314 32 or or CC cord-022526-j9kg00qf 4314 33 other other JJ cord-022526-j9kg00qf 4314 34 colloid colloid NN cord-022526-j9kg00qf 4314 35 administration administration NN cord-022526-j9kg00qf 4314 36 . . . cord-022526-j9kg00qf 4315 1 216 216 CD cord-022526-j9kg00qf 4316 1 Hetastarch Hetastarch NNP cord-022526-j9kg00qf 4316 2 may may MD cord-022526-j9kg00qf 4316 3 prolong prolong VB cord-022526-j9kg00qf 4316 4 bleeding bleed VBG cord-022526-j9kg00qf 4316 5 times time NNS cord-022526-j9kg00qf 4316 6 by by IN cord-022526-j9kg00qf 4316 7 altering alter VBG cord-022526-j9kg00qf 4316 8 von von NNP cord-022526-j9kg00qf 4316 9 Willebrand Willebrand NNP cord-022526-j9kg00qf 4316 10 's 's POS cord-022526-j9kg00qf 4316 11 factor factor NN cord-022526-j9kg00qf 4316 12 function function NN cord-022526-j9kg00qf 4316 13 ; ; : cord-022526-j9kg00qf 4316 14 thus thus RB cord-022526-j9kg00qf 4316 15 one one PRP cord-022526-j9kg00qf 4316 16 should should MD cord-022526-j9kg00qf 4316 17 use use VB cord-022526-j9kg00qf 4316 18 this this DT cord-022526-j9kg00qf 4316 19 synthetic synthetic JJ cord-022526-j9kg00qf 4316 20 colloid colloid NN cord-022526-j9kg00qf 4316 21 cautiously cautiously RB cord-022526-j9kg00qf 4316 22 in in IN cord-022526-j9kg00qf 4316 23 horses horse NNS cord-022526-j9kg00qf 4316 24 with with IN cord-022526-j9kg00qf 4316 25 suspected suspect VBN cord-022526-j9kg00qf 4316 26 coagulopathies coagulopathie NNS cord-022526-j9kg00qf 4316 27 , , , cord-022526-j9kg00qf 4316 28 active active JJ cord-022526-j9kg00qf 4316 29 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4316 30 , , , cord-022526-j9kg00qf 4316 31 or or CC cord-022526-j9kg00qf 4316 32 other other JJ cord-022526-j9kg00qf 4316 33 bleeding bleed VBG cord-022526-j9kg00qf 4316 34 problems problem NNS cord-022526-j9kg00qf 4316 35 . . . cord-022526-j9kg00qf 4317 1 217 217 CD cord-022526-j9kg00qf 4317 2 Control control NN cord-022526-j9kg00qf 4317 3 of of IN cord-022526-j9kg00qf 4317 4 colonic colonic JJ cord-022526-j9kg00qf 4317 5 inflammation inflammation NN cord-022526-j9kg00qf 4317 6 and and CC cord-022526-j9kg00qf 4317 7 secretion secretion NN cord-022526-j9kg00qf 4317 8 is be VBZ cord-022526-j9kg00qf 4317 9 a a DT cord-022526-j9kg00qf 4317 10 difficult difficult JJ cord-022526-j9kg00qf 4317 11 and and CC cord-022526-j9kg00qf 4317 12 poorly poorly RB cord-022526-j9kg00qf 4317 13 studied study VBN cord-022526-j9kg00qf 4317 14 aspect aspect NN cord-022526-j9kg00qf 4317 15 of of IN cord-022526-j9kg00qf 4317 16 equine equine JJ cord-022526-j9kg00qf 4317 17 acute acute JJ cord-022526-j9kg00qf 4317 18 colitis colitis NN cord-022526-j9kg00qf 4317 19 . . . cord-022526-j9kg00qf 4318 1 The the DT cord-022526-j9kg00qf 4318 2 role role NN cord-022526-j9kg00qf 4318 3 of of IN cord-022526-j9kg00qf 4318 4 inflammation inflammation NN cord-022526-j9kg00qf 4318 5 and and CC cord-022526-j9kg00qf 4318 6 mediators mediator NNS cord-022526-j9kg00qf 4318 7 such such JJ cord-022526-j9kg00qf 4318 8 as as IN cord-022526-j9kg00qf 4318 9 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4318 10 as as IN cord-022526-j9kg00qf 4318 11 causes cause NNS cord-022526-j9kg00qf 4318 12 of of IN cord-022526-j9kg00qf 4318 13 fluid fluid JJ cord-022526-j9kg00qf 4318 14 loss loss NN cord-022526-j9kg00qf 4318 15 is be VBZ cord-022526-j9kg00qf 4318 16 well well RB cord-022526-j9kg00qf 4318 17 known know VBN cord-022526-j9kg00qf 4318 18 for for IN cord-022526-j9kg00qf 4318 19 Salmonella Salmonella NNP cord-022526-j9kg00qf 4318 20 and and CC cord-022526-j9kg00qf 4318 21 Clostridium clostridium NN cord-022526-j9kg00qf 4318 22 infections infection NNS cord-022526-j9kg00qf 4318 23 . . . cord-022526-j9kg00qf 4319 1 COX COX NNP cord-022526-j9kg00qf 4319 2 inhibitors inhibitor NNS cord-022526-j9kg00qf 4319 3 ( ( -LRB- cord-022526-j9kg00qf 4319 4 NSAIDs nsaid NNS cord-022526-j9kg00qf 4319 5 ) ) -RRB- cord-022526-j9kg00qf 4319 6 have have VBP cord-022526-j9kg00qf 4319 7 antisecretory antisecretory NN cord-022526-j9kg00qf 4319 8 effects effect NNS cord-022526-j9kg00qf 4319 9 in in IN cord-022526-j9kg00qf 4319 10 the the DT cord-022526-j9kg00qf 4319 11 equine equine JJ cord-022526-j9kg00qf 4319 12 colon colon NN cord-022526-j9kg00qf 4319 13 and and CC cord-022526-j9kg00qf 4319 14 in in IN cord-022526-j9kg00qf 4319 15 models model NNS cord-022526-j9kg00qf 4319 16 of of IN cord-022526-j9kg00qf 4319 17 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4319 18 that that WDT cord-022526-j9kg00qf 4319 19 appear appear VBP cord-022526-j9kg00qf 4319 20 to to TO cord-022526-j9kg00qf 4319 21 extend extend VB cord-022526-j9kg00qf 4319 22 to to IN cord-022526-j9kg00qf 4319 23 clinical clinical JJ cord-022526-j9kg00qf 4319 24 management management NN cord-022526-j9kg00qf 4319 25 of of IN cord-022526-j9kg00qf 4319 26 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4319 27 . . . cord-022526-j9kg00qf 4320 1 16 16 CD cord-022526-j9kg00qf 4320 2 , , , cord-022526-j9kg00qf 4320 3 36 36 CD cord-022526-j9kg00qf 4320 4 , , , cord-022526-j9kg00qf 4320 5 [ [ -LRB- cord-022526-j9kg00qf 4320 6 221 221 CD cord-022526-j9kg00qf 4320 7 ] ] -RRB- cord-022526-j9kg00qf 4320 8 [ [ -LRB- cord-022526-j9kg00qf 4320 9 222 222 CD cord-022526-j9kg00qf 4320 10 ] ] -RRB- cord-022526-j9kg00qf 4320 11 [ [ -LRB- cord-022526-j9kg00qf 4320 12 223 223 CD cord-022526-j9kg00qf 4320 13 ] ] -RRB- cord-022526-j9kg00qf 4321 1 Indeed indeed RB cord-022526-j9kg00qf 4321 2 , , , cord-022526-j9kg00qf 4321 3 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4321 4 commonly commonly RB cord-022526-j9kg00qf 4321 5 are be VBP cord-022526-j9kg00qf 4321 6 administered administer VBN cord-022526-j9kg00qf 4321 7 to to IN cord-022526-j9kg00qf 4321 8 horses horse NNS cord-022526-j9kg00qf 4321 9 with with IN cord-022526-j9kg00qf 4321 10 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4321 11 . . . cord-022526-j9kg00qf 4322 1 However however RB cord-022526-j9kg00qf 4322 2 , , , cord-022526-j9kg00qf 4322 3 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4322 4 such such JJ cord-022526-j9kg00qf 4322 5 as as IN cord-022526-j9kg00qf 4322 6 PGE PGE NNP cord-022526-j9kg00qf 4322 7 2 2 CD cord-022526-j9kg00qf 4322 8 and and CC cord-022526-j9kg00qf 4322 9 PGI PGI NNP cord-022526-j9kg00qf 4322 10 2 2 CD cord-022526-j9kg00qf 4322 11 are be VBP cord-022526-j9kg00qf 4322 12 also also RB cord-022526-j9kg00qf 4322 13 cytoprotective cytoprotective JJ cord-022526-j9kg00qf 4322 14 to to IN cord-022526-j9kg00qf 4322 15 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4322 16 mucosa mucosa JJ cord-022526-j9kg00qf 4322 17 and and CC cord-022526-j9kg00qf 4322 18 critical critical JJ cord-022526-j9kg00qf 4322 19 for for IN cord-022526-j9kg00qf 4322 20 mucosal mucosal JJ cord-022526-j9kg00qf 4322 21 repair repair NN cord-022526-j9kg00qf 4322 22 . . . cord-022526-j9kg00qf 4323 1 172 172 CD cord-022526-j9kg00qf 4324 1 The the DT cord-022526-j9kg00qf 4324 2 doses dose NNS cord-022526-j9kg00qf 4324 3 of of IN cord-022526-j9kg00qf 4324 4 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4324 5 used use VBN cord-022526-j9kg00qf 4324 6 pharmacologically pharmacologically RB cord-022526-j9kg00qf 4324 7 to to TO cord-022526-j9kg00qf 4324 8 inhibit inhibit VB cord-022526-j9kg00qf 4324 9 colonic colonic JJ cord-022526-j9kg00qf 4324 10 inflammation inflammation NN cord-022526-j9kg00qf 4324 11 and and CC cord-022526-j9kg00qf 4324 12 secretion secretion NN cord-022526-j9kg00qf 4324 13 in in IN cord-022526-j9kg00qf 4324 14 fact fact NN cord-022526-j9kg00qf 4324 15 may may MD cord-022526-j9kg00qf 4324 16 be be VB cord-022526-j9kg00qf 4324 17 detrimental detrimental JJ cord-022526-j9kg00qf 4324 18 to to IN cord-022526-j9kg00qf 4324 19 the the DT cord-022526-j9kg00qf 4324 20 mucosa mucosa NN cord-022526-j9kg00qf 4324 21 if if IN cord-022526-j9kg00qf 4324 22 not not RB cord-022526-j9kg00qf 4324 23 used use VBN cord-022526-j9kg00qf 4324 24 judiciously judiciously RB cord-022526-j9kg00qf 4324 25 . . . cord-022526-j9kg00qf 4325 1 NSAIDs nsaid NNS cord-022526-j9kg00qf 4325 2 have have VBP cord-022526-j9kg00qf 4325 3 been be VBN cord-022526-j9kg00qf 4325 4 shown show VBN cord-022526-j9kg00qf 4325 5 to to TO cord-022526-j9kg00qf 4325 6 exacerbate exacerbate VB cord-022526-j9kg00qf 4325 7 colonic colonic JJ cord-022526-j9kg00qf 4325 8 inflammation inflammation NN cord-022526-j9kg00qf 4325 9 in in IN cord-022526-j9kg00qf 4325 10 human human JJ cord-022526-j9kg00qf 4325 11 beings being NNS cord-022526-j9kg00qf 4325 12 with with IN cord-022526-j9kg00qf 4325 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 4325 14 colitis colitis NN cord-022526-j9kg00qf 4325 15 , , , cord-022526-j9kg00qf 4325 16 impede impede VB cord-022526-j9kg00qf 4325 17 mucosal mucosal JJ cord-022526-j9kg00qf 4325 18 healing healing NN cord-022526-j9kg00qf 4325 19 in in IN cord-022526-j9kg00qf 4325 20 several several JJ cord-022526-j9kg00qf 4325 21 models model NNS cord-022526-j9kg00qf 4325 22 of of IN cord-022526-j9kg00qf 4325 23 mucosal mucosal JJ cord-022526-j9kg00qf 4325 24 injury injury NN cord-022526-j9kg00qf 4325 25 , , , cord-022526-j9kg00qf 4325 26 and and CC cord-022526-j9kg00qf 4325 27 have have VBP cord-022526-j9kg00qf 4325 28 well well RB cord-022526-j9kg00qf 4325 29 - - HYPH cord-022526-j9kg00qf 4325 30 documented document VBN cord-022526-j9kg00qf 4325 31 detrimental detrimental JJ cord-022526-j9kg00qf 4325 32 effects effect NNS cord-022526-j9kg00qf 4325 33 on on IN cord-022526-j9kg00qf 4325 34 colonic colonic JJ cord-022526-j9kg00qf 4325 35 mucosa mucosa NN cord-022526-j9kg00qf 4325 36 in in IN cord-022526-j9kg00qf 4325 37 horses horse NNS cord-022526-j9kg00qf 4325 38 . . . cord-022526-j9kg00qf 4326 1 164 164 CD cord-022526-j9kg00qf 4326 2 , , , cord-022526-j9kg00qf 4326 3 172 172 CD cord-022526-j9kg00qf 4326 4 , , , cord-022526-j9kg00qf 4326 5 224 224 CD cord-022526-j9kg00qf 4327 1 In in IN cord-022526-j9kg00qf 4327 2 addition addition NN cord-022526-j9kg00qf 4327 3 to to IN cord-022526-j9kg00qf 4327 4 toxicity toxicity NN cord-022526-j9kg00qf 4327 5 to to IN cord-022526-j9kg00qf 4327 6 the the DT cord-022526-j9kg00qf 4327 7 colonic colonic JJ cord-022526-j9kg00qf 4327 8 mucosa mucosa NN cord-022526-j9kg00qf 4327 9 , , , cord-022526-j9kg00qf 4327 10 gastric gastric JJ cord-022526-j9kg00qf 4327 11 ulceration ulceration NN cord-022526-j9kg00qf 4327 12 is be VBZ cord-022526-j9kg00qf 4327 13 not not RB cord-022526-j9kg00qf 4327 14 unusual unusual JJ cord-022526-j9kg00qf 4327 15 in in IN cord-022526-j9kg00qf 4327 16 horses horse NNS cord-022526-j9kg00qf 4327 17 with with IN cord-022526-j9kg00qf 4327 18 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4327 19 and and CC cord-022526-j9kg00qf 4327 20 may may MD cord-022526-j9kg00qf 4327 21 be be VB cord-022526-j9kg00qf 4327 22 related relate VBN cord-022526-j9kg00qf 4327 23 to to IN cord-022526-j9kg00qf 4327 24 treatment treatment NN cord-022526-j9kg00qf 4327 25 with with IN cord-022526-j9kg00qf 4327 26 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4327 27 . . . cord-022526-j9kg00qf 4328 1 In in IN cord-022526-j9kg00qf 4328 2 addition addition NN cord-022526-j9kg00qf 4328 3 to to IN cord-022526-j9kg00qf 4328 4 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4328 5 , , , cord-022526-j9kg00qf 4328 6 other other JJ cord-022526-j9kg00qf 4328 7 drugs drug NNS cord-022526-j9kg00qf 4328 8 occasionally occasionally RB cord-022526-j9kg00qf 4328 9 are be VBP cord-022526-j9kg00qf 4328 10 used use VBN cord-022526-j9kg00qf 4328 11 as as IN cord-022526-j9kg00qf 4328 12 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 4328 13 or or CC cord-022526-j9kg00qf 4328 14 antisecretory antisecretory NN cord-022526-j9kg00qf 4328 15 therapy therapy NN cord-022526-j9kg00qf 4328 16 . . . cord-022526-j9kg00qf 4329 1 Metronidazole Metronidazole NNP cord-022526-j9kg00qf 4329 2 has have VBZ cord-022526-j9kg00qf 4329 3 beneficial beneficial JJ cord-022526-j9kg00qf 4329 4 effects effect NNS cord-022526-j9kg00qf 4329 5 in in IN cord-022526-j9kg00qf 4329 6 experimental experimental JJ cord-022526-j9kg00qf 4329 7 models model NNS cord-022526-j9kg00qf 4329 8 of of IN cord-022526-j9kg00qf 4329 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4329 10 inflammation inflammation NN cord-022526-j9kg00qf 4329 11 , , , cord-022526-j9kg00qf 4329 12 including include VBG cord-022526-j9kg00qf 4329 13 NSAID NSAID NNP cord-022526-j9kg00qf 4329 14 toxicity toxicity NN cord-022526-j9kg00qf 4329 15 176 176 CD cord-022526-j9kg00qf 4329 16 and and CC cord-022526-j9kg00qf 4329 17 may may MD cord-022526-j9kg00qf 4329 18 be be VB cord-022526-j9kg00qf 4329 19 useful useful JJ cord-022526-j9kg00qf 4329 20 for for IN cord-022526-j9kg00qf 4329 21 treating treat VBG cord-022526-j9kg00qf 4329 22 horses horse NNS cord-022526-j9kg00qf 4329 23 with with IN cord-022526-j9kg00qf 4329 24 colitis colitis NN cord-022526-j9kg00qf 4329 25 , , , cord-022526-j9kg00qf 4329 26 but but CC cord-022526-j9kg00qf 4329 27 evidence evidence NN cord-022526-j9kg00qf 4329 28 supporting support VBG cord-022526-j9kg00qf 4329 29 its -PRON- PRP$ cord-022526-j9kg00qf 4329 30 use use NN cord-022526-j9kg00qf 4329 31 is be VBZ cord-022526-j9kg00qf 4329 32 lacking lack VBG cord-022526-j9kg00qf 4329 33 . . . cord-022526-j9kg00qf 4330 1 Bismuth bismuth JJ cord-022526-j9kg00qf 4330 2 subsalicylate subsalicylate NN cord-022526-j9kg00qf 4330 3 solutions solution NNS cord-022526-j9kg00qf 4330 4 administered administer VBN cord-022526-j9kg00qf 4330 5 orally orally RB cord-022526-j9kg00qf 4330 6 often often RB cord-022526-j9kg00qf 4330 7 are be VBP cord-022526-j9kg00qf 4330 8 used use VBN cord-022526-j9kg00qf 4330 9 to to TO cord-022526-j9kg00qf 4330 10 decrease decrease VB cord-022526-j9kg00qf 4330 11 inflammation inflammation NN cord-022526-j9kg00qf 4330 12 and and CC cord-022526-j9kg00qf 4330 13 secretion secretion NN cord-022526-j9kg00qf 4330 14 in in IN cord-022526-j9kg00qf 4330 15 the the DT cord-022526-j9kg00qf 4330 16 colon colon NN cord-022526-j9kg00qf 4330 17 . . . cord-022526-j9kg00qf 4331 1 In in IN cord-022526-j9kg00qf 4331 2 adult adult NN cord-022526-j9kg00qf 4331 3 horses horse NNS cord-022526-j9kg00qf 4331 4 the the DT cord-022526-j9kg00qf 4331 5 volume volume NN cord-022526-j9kg00qf 4331 6 of of IN cord-022526-j9kg00qf 4331 7 solution solution NN cord-022526-j9kg00qf 4331 8 necessary necessary JJ cord-022526-j9kg00qf 4331 9 to to TO cord-022526-j9kg00qf 4331 10 be be VB cord-022526-j9kg00qf 4331 11 beneficial beneficial JJ cord-022526-j9kg00qf 4331 12 is be VBZ cord-022526-j9kg00qf 4331 13 large large JJ cord-022526-j9kg00qf 4331 14 ( ( -LRB- cord-022526-j9kg00qf 4331 15 3 3 CD cord-022526-j9kg00qf 4331 16 to to IN cord-022526-j9kg00qf 4331 17 4 4 CD cord-022526-j9kg00qf 4331 18 L l NN cord-022526-j9kg00qf 4331 19 every every DT cord-022526-j9kg00qf 4331 20 4 4 CD cord-022526-j9kg00qf 4331 21 to to TO cord-022526-j9kg00qf 4331 22 6 6 CD cord-022526-j9kg00qf 4331 23 hours hour NNS cord-022526-j9kg00qf 4331 24 ) ) -RRB- cord-022526-j9kg00qf 4331 25 . . . cord-022526-j9kg00qf 4332 1 Often often RB cord-022526-j9kg00qf 4332 2 the the DT cord-022526-j9kg00qf 4332 3 solution solution NN cord-022526-j9kg00qf 4332 4 is be VBZ cord-022526-j9kg00qf 4332 5 administered administer VBN cord-022526-j9kg00qf 4332 6 twice twice RB cord-022526-j9kg00qf 4332 7 daily daily RB cord-022526-j9kg00qf 4332 8 instead instead RB cord-022526-j9kg00qf 4332 9 of of IN cord-022526-j9kg00qf 4332 10 4 4 CD cord-022526-j9kg00qf 4332 11 to to TO cord-022526-j9kg00qf 4332 12 6 6 CD cord-022526-j9kg00qf 4332 13 times time NNS cord-022526-j9kg00qf 4332 14 daily daily RB cord-022526-j9kg00qf 4332 15 . . . cord-022526-j9kg00qf 4333 1 If if IN cord-022526-j9kg00qf 4333 2 one one PRP cord-022526-j9kg00qf 4333 3 does do VBZ cord-022526-j9kg00qf 4333 4 not not RB cord-022526-j9kg00qf 4333 5 achieve achieve VB cord-022526-j9kg00qf 4333 6 a a DT cord-022526-j9kg00qf 4333 7 beneficial beneficial JJ cord-022526-j9kg00qf 4333 8 effect effect NN cord-022526-j9kg00qf 4333 9 within within IN cord-022526-j9kg00qf 4333 10 3 3 CD cord-022526-j9kg00qf 4333 11 to to TO cord-022526-j9kg00qf 4333 12 4 4 CD cord-022526-j9kg00qf 4333 13 days day NNS cord-022526-j9kg00qf 4333 14 of of IN cord-022526-j9kg00qf 4333 15 treatment treatment NN cord-022526-j9kg00qf 4333 16 , , , cord-022526-j9kg00qf 4333 17 one one PRP cord-022526-j9kg00qf 4333 18 should should MD cord-022526-j9kg00qf 4333 19 discontinue discontinue VB cord-022526-j9kg00qf 4333 20 administration administration NN cord-022526-j9kg00qf 4333 21 of of IN cord-022526-j9kg00qf 4333 22 bismuth bismuth NNP cord-022526-j9kg00qf 4333 23 subsalicylate subsalicylate NNP cord-022526-j9kg00qf 4333 24 solution solution NN cord-022526-j9kg00qf 4333 25 . . . cord-022526-j9kg00qf 4334 1 One one PRP cord-022526-j9kg00qf 4334 2 can can MD cord-022526-j9kg00qf 4334 3 administer administer VB cord-022526-j9kg00qf 4334 4 the the DT cord-022526-j9kg00qf 4334 5 treatment treatment NN cord-022526-j9kg00qf 4334 6 more more RBR cord-022526-j9kg00qf 4334 7 frequently frequently RB cord-022526-j9kg00qf 4334 8 in in IN cord-022526-j9kg00qf 4334 9 foals foal NNS cord-022526-j9kg00qf 4334 10 , , , cord-022526-j9kg00qf 4334 11 and and CC cord-022526-j9kg00qf 4334 12 clinical clinical JJ cord-022526-j9kg00qf 4334 13 improvement improvement NN cord-022526-j9kg00qf 4334 14 occurs occur VBZ cord-022526-j9kg00qf 4334 15 more more RBR cord-022526-j9kg00qf 4334 16 often often RB cord-022526-j9kg00qf 4334 17 in in IN cord-022526-j9kg00qf 4334 18 foals foal NNS cord-022526-j9kg00qf 4334 19 than than IN cord-022526-j9kg00qf 4334 20 in in IN cord-022526-j9kg00qf 4334 21 adult adult NN cord-022526-j9kg00qf 4334 22 horses horse NNS cord-022526-j9kg00qf 4334 23 . . . cord-022526-j9kg00qf 4335 1 In in IN cord-022526-j9kg00qf 4335 2 light light NN cord-022526-j9kg00qf 4335 3 of of IN cord-022526-j9kg00qf 4335 4 the the DT cord-022526-j9kg00qf 4335 5 role role NN cord-022526-j9kg00qf 4335 6 of of IN cord-022526-j9kg00qf 4335 7 reactive reactive JJ cord-022526-j9kg00qf 4335 8 oxygen oxygen NN cord-022526-j9kg00qf 4335 9 metabolites metabolite NNS cord-022526-j9kg00qf 4335 10 in in IN cord-022526-j9kg00qf 4335 11 colonic colonic JJ cord-022526-j9kg00qf 4335 12 inflammation inflammation NN cord-022526-j9kg00qf 4335 13 , , , cord-022526-j9kg00qf 4335 14 free free JJ cord-022526-j9kg00qf 4335 15 radical radical JJ cord-022526-j9kg00qf 4335 16 scavengers scavenger NNS cord-022526-j9kg00qf 4335 17 have have VBP cord-022526-j9kg00qf 4335 18 been be VBN cord-022526-j9kg00qf 4335 19 advocated advocate VBN cord-022526-j9kg00qf 4335 20 to to TO cord-022526-j9kg00qf 4335 21 reduce reduce VB cord-022526-j9kg00qf 4335 22 the the DT cord-022526-j9kg00qf 4335 23 effects effect NNS cord-022526-j9kg00qf 4335 24 of of IN cord-022526-j9kg00qf 4335 25 these these DT cord-022526-j9kg00qf 4335 26 molecules molecule NNS cord-022526-j9kg00qf 4335 27 . . . cord-022526-j9kg00qf 4336 1 Sulfasalazine Sulfasalazine NNP cord-022526-j9kg00qf 4336 2 metabolites metabolite NNS cord-022526-j9kg00qf 4336 3 have have VBP cord-022526-j9kg00qf 4336 4 been be VBN cord-022526-j9kg00qf 4336 5 shown show VBN cord-022526-j9kg00qf 4336 6 to to TO cord-022526-j9kg00qf 4336 7 reduce reduce VB cord-022526-j9kg00qf 4336 8 reactive reactive JJ cord-022526-j9kg00qf 4336 9 oxygen oxygen NN cord-022526-j9kg00qf 4336 10 metabolite metabolite NN cord-022526-j9kg00qf 4336 11 - - HYPH cord-022526-j9kg00qf 4336 12 induced induce VBN cord-022526-j9kg00qf 4336 13 colonic colonic JJ cord-022526-j9kg00qf 4336 14 inflammation inflammation NN cord-022526-j9kg00qf 4336 15 in in IN cord-022526-j9kg00qf 4336 16 other other JJ cord-022526-j9kg00qf 4336 17 species specie NNS cord-022526-j9kg00qf 4336 18 , , , cord-022526-j9kg00qf 4336 19 176 176 CD cord-022526-j9kg00qf 4336 20 and and CC cord-022526-j9kg00qf 4336 21 sulfasalazine sulfasalazine NN cord-022526-j9kg00qf 4336 22 has have VBZ cord-022526-j9kg00qf 4336 23 been be VBN cord-022526-j9kg00qf 4336 24 used use VBN cord-022526-j9kg00qf 4336 25 to to TO cord-022526-j9kg00qf 4336 26 treat treat VB cord-022526-j9kg00qf 4336 27 chronic chronic JJ cord-022526-j9kg00qf 4336 28 inflammatory inflammatory JJ cord-022526-j9kg00qf 4336 29 disease disease NN cord-022526-j9kg00qf 4336 30 in in IN cord-022526-j9kg00qf 4336 31 horses horse NNS cord-022526-j9kg00qf 4336 32 but but CC cord-022526-j9kg00qf 4336 33 has have VBZ cord-022526-j9kg00qf 4336 34 not not RB cord-022526-j9kg00qf 4336 35 been be VBN cord-022526-j9kg00qf 4336 36 used use VBN cord-022526-j9kg00qf 4336 37 to to TO cord-022526-j9kg00qf 4336 38 treat treat VB cord-022526-j9kg00qf 4336 39 acute acute JJ cord-022526-j9kg00qf 4336 40 colitis colitis NN cord-022526-j9kg00qf 4336 41 . . . cord-022526-j9kg00qf 4337 1 The the DT cord-022526-j9kg00qf 4337 2 only only JJ cord-022526-j9kg00qf 4337 3 free free JJ cord-022526-j9kg00qf 4337 4 radical radical JJ cord-022526-j9kg00qf 4337 5 scavenger scavenger NN cord-022526-j9kg00qf 4337 6 used use VBN cord-022526-j9kg00qf 4337 7 commonly commonly RB cord-022526-j9kg00qf 4337 8 in in IN cord-022526-j9kg00qf 4337 9 horses horse NNS cord-022526-j9kg00qf 4337 10 with with IN cord-022526-j9kg00qf 4337 11 colitis colitis NN cord-022526-j9kg00qf 4337 12 is be VBZ cord-022526-j9kg00qf 4337 13 dimethyl dimethyl NN cord-022526-j9kg00qf 4337 14 sulfoxide sulfoxide NN cord-022526-j9kg00qf 4337 15 , , , cord-022526-j9kg00qf 4337 16 which which WDT cord-022526-j9kg00qf 4337 17 at at IN cord-022526-j9kg00qf 4337 18 a a DT cord-022526-j9kg00qf 4337 19 dosage dosage NN cord-022526-j9kg00qf 4337 20 of of IN cord-022526-j9kg00qf 4337 21 0.1 0.1 CD cord-022526-j9kg00qf 4337 22 to to TO cord-022526-j9kg00qf 4337 23 1.0 1.0 CD cord-022526-j9kg00qf 4337 24 g g NN cord-022526-j9kg00qf 4337 25 / / SYM cord-022526-j9kg00qf 4337 26 kg kg CC cord-022526-j9kg00qf 4337 27 intravenously intravenously RB cord-022526-j9kg00qf 4337 28 every every DT cord-022526-j9kg00qf 4337 29 12 12 CD cord-022526-j9kg00qf 4337 30 to to TO cord-022526-j9kg00qf 4337 31 24 24 CD cord-022526-j9kg00qf 4337 32 hours hour NNS cord-022526-j9kg00qf 4337 33 in in IN cord-022526-j9kg00qf 4337 34 a a DT cord-022526-j9kg00qf 4337 35 10 10 CD cord-022526-j9kg00qf 4337 36 % % NN cord-022526-j9kg00qf 4337 37 solution solution NN cord-022526-j9kg00qf 4337 38 has have VBZ cord-022526-j9kg00qf 4337 39 been be VBN cord-022526-j9kg00qf 4337 40 used use VBN cord-022526-j9kg00qf 4337 41 in in IN cord-022526-j9kg00qf 4337 42 clinical clinical JJ cord-022526-j9kg00qf 4337 43 cases case NNS cord-022526-j9kg00qf 4337 44 of of IN cord-022526-j9kg00qf 4337 45 colitis colitis NN cord-022526-j9kg00qf 4337 46 , , , cord-022526-j9kg00qf 4337 47 but but CC cord-022526-j9kg00qf 4337 48 evidence evidence NN cord-022526-j9kg00qf 4337 49 of of IN cord-022526-j9kg00qf 4337 50 efficacy efficacy NN cord-022526-j9kg00qf 4337 51 has have VBZ cord-022526-j9kg00qf 4337 52 not not RB cord-022526-j9kg00qf 4337 53 been be VBN cord-022526-j9kg00qf 4337 54 established establish VBN cord-022526-j9kg00qf 4337 55 . . . cord-022526-j9kg00qf 4338 1 Systemic systemic JJ cord-022526-j9kg00qf 4338 2 inflammatory inflammatory JJ cord-022526-j9kg00qf 4338 3 response response NN cord-022526-j9kg00qf 4338 4 syndrome syndrome NN cord-022526-j9kg00qf 4338 5 associated associate VBN cord-022526-j9kg00qf 4338 6 with with IN cord-022526-j9kg00qf 4338 7 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4338 8 frequently frequently RB cord-022526-j9kg00qf 4338 9 occurs occur VBZ cord-022526-j9kg00qf 4338 10 in in IN cord-022526-j9kg00qf 4338 11 patients patient NNS cord-022526-j9kg00qf 4338 12 with with IN cord-022526-j9kg00qf 4338 13 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4338 14 . . . cord-022526-j9kg00qf 4339 1 The the DT cord-022526-j9kg00qf 4339 2 principles principle NNS cord-022526-j9kg00qf 4339 3 of of IN cord-022526-j9kg00qf 4339 4 therapy therapy NN cord-022526-j9kg00qf 4339 5 for for IN cord-022526-j9kg00qf 4339 6 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4339 7 are be VBP cord-022526-j9kg00qf 4339 8 covered cover VBN cord-022526-j9kg00qf 4339 9 in in IN cord-022526-j9kg00qf 4339 10 detail detail NN cord-022526-j9kg00qf 4339 11 elsewhere elsewhere RB cord-022526-j9kg00qf 4339 12 in in IN cord-022526-j9kg00qf 4339 13 this this DT cord-022526-j9kg00qf 4339 14 chapter chapter NN cord-022526-j9kg00qf 4339 15 . . . cord-022526-j9kg00qf 4340 1 Oral oral JJ cord-022526-j9kg00qf 4340 2 administration administration NN cord-022526-j9kg00qf 4340 3 of of IN cord-022526-j9kg00qf 4340 4 activated activate VBN cord-022526-j9kg00qf 4340 5 charcoal charcoal NN cord-022526-j9kg00qf 4340 6 and and CC cord-022526-j9kg00qf 4340 7 mineral mineral NN cord-022526-j9kg00qf 4340 8 oil oil NN cord-022526-j9kg00qf 4340 9 is be VBZ cord-022526-j9kg00qf 4340 10 used use VBN cord-022526-j9kg00qf 4340 11 commonly commonly RB cord-022526-j9kg00qf 4340 12 to to TO cord-022526-j9kg00qf 4340 13 reduce reduce VB cord-022526-j9kg00qf 4340 14 absorption absorption NN cord-022526-j9kg00qf 4340 15 of of IN cord-022526-j9kg00qf 4340 16 endotoxin endotoxin NN cord-022526-j9kg00qf 4340 17 in in IN cord-022526-j9kg00qf 4340 18 horses horse NNS cord-022526-j9kg00qf 4340 19 with with IN cord-022526-j9kg00qf 4340 20 colitis colitis NN cord-022526-j9kg00qf 4340 21 . . . cord-022526-j9kg00qf 4341 1 Low low JJ cord-022526-j9kg00qf 4341 2 doses dose NNS cord-022526-j9kg00qf 4341 3 of of IN cord-022526-j9kg00qf 4341 4 NSAIDs nsaid NNS cord-022526-j9kg00qf 4341 5 ( ( -LRB- cord-022526-j9kg00qf 4341 6 such such JJ cord-022526-j9kg00qf 4341 7 as as IN cord-022526-j9kg00qf 4341 8 flunixin flunixin NNP cord-022526-j9kg00qf 4341 9 meglumine meglumine NNP cord-022526-j9kg00qf 4341 10 at at IN cord-022526-j9kg00qf 4341 11 0.1 0.1 CD cord-022526-j9kg00qf 4341 12 to to IN cord-022526-j9kg00qf 4341 13 0.25 0.25 CD cord-022526-j9kg00qf 4341 14 mg mg NN cord-022526-j9kg00qf 4341 15 / / SYM cord-022526-j9kg00qf 4341 16 kg kg CC cord-022526-j9kg00qf 4341 17 intravenously intravenously RB cord-022526-j9kg00qf 4341 18 every every DT cord-022526-j9kg00qf 4341 19 6 6 CD cord-022526-j9kg00qf 4341 20 to to TO cord-022526-j9kg00qf 4341 21 8 8 CD cord-022526-j9kg00qf 4341 22 hours hour NNS cord-022526-j9kg00qf 4341 23 ) ) -RRB- cord-022526-j9kg00qf 4342 1 inhibit inhibit VB cord-022526-j9kg00qf 4342 2 eicosanoid eicosanoid JJ cord-022526-j9kg00qf 4342 3 synthesis synthesis NN cord-022526-j9kg00qf 4342 4 induced induce VBN cord-022526-j9kg00qf 4342 5 by by IN cord-022526-j9kg00qf 4342 6 endotoxin endotoxin NN cord-022526-j9kg00qf 4342 7 . . . cord-022526-j9kg00qf 4343 1 In in IN cord-022526-j9kg00qf 4343 2 addition addition NN cord-022526-j9kg00qf 4343 3 , , , cord-022526-j9kg00qf 4343 4 administration administration NN cord-022526-j9kg00qf 4343 5 of of IN cord-022526-j9kg00qf 4343 6 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4343 7 prevents prevent VBZ cord-022526-j9kg00qf 4343 8 laminitis laminitis NN cord-022526-j9kg00qf 4343 9 from from IN cord-022526-j9kg00qf 4343 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4343 11 , , , cord-022526-j9kg00qf 4343 12 a a DT cord-022526-j9kg00qf 4343 13 devastating devastating JJ cord-022526-j9kg00qf 4343 14 complication complication NN cord-022526-j9kg00qf 4343 15 of of IN cord-022526-j9kg00qf 4343 16 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4343 17 . . . cord-022526-j9kg00qf 4344 1 One one PRP cord-022526-j9kg00qf 4344 2 must must MD cord-022526-j9kg00qf 4344 3 remember remember VB cord-022526-j9kg00qf 4344 4 that that IN cord-022526-j9kg00qf 4344 5 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 4344 6 are be VBP cord-022526-j9kg00qf 4344 7 important important JJ cord-022526-j9kg00qf 4344 8 for for IN cord-022526-j9kg00qf 4344 9 mucosal mucosal JJ cord-022526-j9kg00qf 4344 10 healing healing NN cord-022526-j9kg00qf 4344 11 and and CC cord-022526-j9kg00qf 4344 12 may may MD cord-022526-j9kg00qf 4344 13 worsen worsen VB cord-022526-j9kg00qf 4344 14 mucosal mucosal JJ cord-022526-j9kg00qf 4344 15 injury injury NN cord-022526-j9kg00qf 4344 16 in in IN cord-022526-j9kg00qf 4344 17 colitis colitis NN cord-022526-j9kg00qf 4344 18 . . . cord-022526-j9kg00qf 4345 1 Although although IN cord-022526-j9kg00qf 4345 2 the the DT cord-022526-j9kg00qf 4345 3 benefits benefit NNS cord-022526-j9kg00qf 4345 4 of of IN cord-022526-j9kg00qf 4345 5 low low JJ cord-022526-j9kg00qf 4345 6 doses dose NNS cord-022526-j9kg00qf 4345 7 of of IN cord-022526-j9kg00qf 4345 8 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4345 9 administered administer VBN cord-022526-j9kg00qf 4345 10 to to IN cord-022526-j9kg00qf 4345 11 horses horse NNS cord-022526-j9kg00qf 4345 12 with with IN cord-022526-j9kg00qf 4345 13 systemic systemic JJ cord-022526-j9kg00qf 4345 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 4345 15 response response NN cord-022526-j9kg00qf 4345 16 syndrome syndrome NN cord-022526-j9kg00qf 4345 17 are be VBP cord-022526-j9kg00qf 4345 18 believed believe VBN cord-022526-j9kg00qf 4345 19 to to TO cord-022526-j9kg00qf 4345 20 outweigh outweigh VB cord-022526-j9kg00qf 4345 21 the the DT cord-022526-j9kg00qf 4345 22 risks risk NNS cord-022526-j9kg00qf 4345 23 of of IN cord-022526-j9kg00qf 4345 24 worsening worsen VBG cord-022526-j9kg00qf 4345 25 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4345 26 damage damage NN cord-022526-j9kg00qf 4345 27 , , , cord-022526-j9kg00qf 4345 28 judicious judicious JJ cord-022526-j9kg00qf 4345 29 use use NN cord-022526-j9kg00qf 4345 30 is be VBZ cord-022526-j9kg00qf 4345 31 recommended recommend VBN cord-022526-j9kg00qf 4345 32 . . . cord-022526-j9kg00qf 4346 1 Sucralfate sucralfate JJ cord-022526-j9kg00qf 4346 2 ( ( -LRB- cord-022526-j9kg00qf 4346 3 20 20 CD cord-022526-j9kg00qf 4346 4 mg mg NN cord-022526-j9kg00qf 4346 5 / / SYM cord-022526-j9kg00qf 4346 6 kg kg CC cord-022526-j9kg00qf 4346 7 orally orally RB cord-022526-j9kg00qf 4346 8 every every DT cord-022526-j9kg00qf 4346 9 6 6 CD cord-022526-j9kg00qf 4346 10 hours hour NNS cord-022526-j9kg00qf 4346 11 ) ) -RRB- cord-022526-j9kg00qf 4346 12 has have VBZ cord-022526-j9kg00qf 4346 13 been be VBN cord-022526-j9kg00qf 4346 14 advocated advocate VBN cord-022526-j9kg00qf 4346 15 to to TO cord-022526-j9kg00qf 4346 16 aid aid VB cord-022526-j9kg00qf 4346 17 in in IN cord-022526-j9kg00qf 4346 18 healing heal VBG cord-022526-j9kg00qf 4346 19 the the DT cord-022526-j9kg00qf 4346 20 colonic colonic JJ cord-022526-j9kg00qf 4346 21 mucosa mucosa NN cord-022526-j9kg00qf 4346 22 , , , cord-022526-j9kg00qf 4346 23 but but CC cord-022526-j9kg00qf 4346 24 the the DT cord-022526-j9kg00qf 4346 25 efficacy efficacy NN cord-022526-j9kg00qf 4346 26 in in IN cord-022526-j9kg00qf 4346 27 the the DT cord-022526-j9kg00qf 4346 28 large large JJ cord-022526-j9kg00qf 4346 29 intestine intestine NN cord-022526-j9kg00qf 4346 30 is be VBZ cord-022526-j9kg00qf 4346 31 questionable questionable JJ cord-022526-j9kg00qf 4346 32 . . . cord-022526-j9kg00qf 4347 1 94 94 CD cord-022526-j9kg00qf 4347 2 Misoprostol Misoprostol NNP cord-022526-j9kg00qf 4347 3 ( ( -LRB- cord-022526-j9kg00qf 4347 4 2 2 CD cord-022526-j9kg00qf 4347 5 µg µg NN cord-022526-j9kg00qf 4347 6 / / SYM cord-022526-j9kg00qf 4347 7 kg kg CC cord-022526-j9kg00qf 4347 8 orally orally RB cord-022526-j9kg00qf 4347 9 3 3 CD cord-022526-j9kg00qf 4347 10 to to IN cord-022526-j9kg00qf 4347 11 4 4 CD cord-022526-j9kg00qf 4347 12 times time NNS cord-022526-j9kg00qf 4347 13 daily daily JJ cord-022526-j9kg00qf 4347 14 ) ) -RRB- cord-022526-j9kg00qf 4347 15 and and CC cord-022526-j9kg00qf 4347 16 other other JJ cord-022526-j9kg00qf 4347 17 synthetic synthetic JJ cord-022526-j9kg00qf 4347 18 PGE PGE NNP cord-022526-j9kg00qf 4347 19 analogs analog NNS cord-022526-j9kg00qf 4347 20 have have VBP cord-022526-j9kg00qf 4347 21 been be VBN cord-022526-j9kg00qf 4347 22 shown show VBN cord-022526-j9kg00qf 4347 23 in in IN cord-022526-j9kg00qf 4347 24 several several JJ cord-022526-j9kg00qf 4347 25 species specie NNS cord-022526-j9kg00qf 4347 26 including include VBG cord-022526-j9kg00qf 4347 27 horses horse NNS cord-022526-j9kg00qf 4347 28 to to TO cord-022526-j9kg00qf 4347 29 enhance enhance VB cord-022526-j9kg00qf 4347 30 mucosal mucosal JJ cord-022526-j9kg00qf 4347 31 healing healing NN cord-022526-j9kg00qf 4347 32 in in IN cord-022526-j9kg00qf 4347 33 the the DT cord-022526-j9kg00qf 4347 34 intestine intestine NN cord-022526-j9kg00qf 4347 35 and and CC cord-022526-j9kg00qf 4347 36 promote promote VB cord-022526-j9kg00qf 4347 37 recovery recovery NN cord-022526-j9kg00qf 4347 38 in in IN cord-022526-j9kg00qf 4347 39 experimental experimental JJ cord-022526-j9kg00qf 4347 40 models model NNS cord-022526-j9kg00qf 4347 41 of of IN cord-022526-j9kg00qf 4347 42 colitis colitis NN cord-022526-j9kg00qf 4347 43 . . . cord-022526-j9kg00qf 4348 1 225 225 CD cord-022526-j9kg00qf 4348 2 Misoprostol Misoprostol NNP cord-022526-j9kg00qf 4348 3 may may MD cord-022526-j9kg00qf 4348 4 be be VB cord-022526-j9kg00qf 4348 5 particularly particularly RB cord-022526-j9kg00qf 4348 6 useful useful JJ cord-022526-j9kg00qf 4348 7 for for IN cord-022526-j9kg00qf 4348 8 treating treat VBG cord-022526-j9kg00qf 4348 9 NSAID nsaid NN cord-022526-j9kg00qf 4348 10 toxicity toxicity NN cord-022526-j9kg00qf 4348 11 , , , cord-022526-j9kg00qf 4348 12 the the DT cord-022526-j9kg00qf 4348 13 generalized generalized JJ cord-022526-j9kg00qf 4348 14 form form NN cord-022526-j9kg00qf 4348 15 or or CC cord-022526-j9kg00qf 4348 16 RDC RDC NNP cord-022526-j9kg00qf 4348 17 . . . cord-022526-j9kg00qf 4349 1 However however RB cord-022526-j9kg00qf 4349 2 , , , cord-022526-j9kg00qf 4349 3 the the DT cord-022526-j9kg00qf 4349 4 efficacy efficacy NN cord-022526-j9kg00qf 4349 5 of of IN cord-022526-j9kg00qf 4349 6 misoprostil misoprostil NNP cord-022526-j9kg00qf 4349 7 for for IN cord-022526-j9kg00qf 4349 8 hastening hasten VBG cord-022526-j9kg00qf 4349 9 mucosal mucosal JJ cord-022526-j9kg00qf 4349 10 healing healing NN cord-022526-j9kg00qf 4349 11 is be VBZ cord-022526-j9kg00qf 4349 12 clinically clinically RB cord-022526-j9kg00qf 4349 13 unproven unproven JJ cord-022526-j9kg00qf 4349 14 in in IN cord-022526-j9kg00qf 4349 15 equine equine JJ cord-022526-j9kg00qf 4349 16 colitis colitis NN cord-022526-j9kg00qf 4349 17 . . . cord-022526-j9kg00qf 4350 1 The the DT cord-022526-j9kg00qf 4350 2 primary primary JJ cord-022526-j9kg00qf 4350 3 drawbacks drawback NNS cord-022526-j9kg00qf 4350 4 of of IN cord-022526-j9kg00qf 4350 5 prostaglandin prostaglandin NN cord-022526-j9kg00qf 4350 6 analogs analog NNS cord-022526-j9kg00qf 4350 7 such such JJ cord-022526-j9kg00qf 4350 8 as as IN cord-022526-j9kg00qf 4350 9 misoprostol misoprostol NNP cord-022526-j9kg00qf 4350 10 are be VBP cord-022526-j9kg00qf 4350 11 the the DT cord-022526-j9kg00qf 4350 12 side side JJ cord-022526-j9kg00qf 4350 13 effects effect NNS cord-022526-j9kg00qf 4350 14 of of IN cord-022526-j9kg00qf 4350 15 the the DT cord-022526-j9kg00qf 4350 16 drug drug NN cord-022526-j9kg00qf 4350 17 , , , cord-022526-j9kg00qf 4350 18 including include VBG cord-022526-j9kg00qf 4350 19 abdominal abdominal JJ cord-022526-j9kg00qf 4350 20 cramping cramping NN cord-022526-j9kg00qf 4350 21 , , , cord-022526-j9kg00qf 4350 22 diarrhea diarrhea NN cord-022526-j9kg00qf 4350 23 , , , cord-022526-j9kg00qf 4350 24 sweating sweating NN cord-022526-j9kg00qf 4350 25 , , , cord-022526-j9kg00qf 4350 26 and and CC cord-022526-j9kg00qf 4350 27 abortion abortion NN cord-022526-j9kg00qf 4350 28 in in IN cord-022526-j9kg00qf 4350 29 pregnant pregnant JJ cord-022526-j9kg00qf 4350 30 mares mare NNS cord-022526-j9kg00qf 4350 31 . . . cord-022526-j9kg00qf 4351 1 One one PRP cord-022526-j9kg00qf 4351 2 can can MD cord-022526-j9kg00qf 4351 3 add add VB cord-022526-j9kg00qf 4351 4 psyllium psyllium NN cord-022526-j9kg00qf 4351 5 mucilloid mucilloid NN cord-022526-j9kg00qf 4351 6 to to IN cord-022526-j9kg00qf 4351 7 the the DT cord-022526-j9kg00qf 4351 8 diet diet NN cord-022526-j9kg00qf 4351 9 ( ( -LRB- cord-022526-j9kg00qf 4351 10 5 5 CD cord-022526-j9kg00qf 4351 11 tablespoons tablespoon NNS cord-022526-j9kg00qf 4351 12 once once RB cord-022526-j9kg00qf 4351 13 or or CC cord-022526-j9kg00qf 4351 14 twice twice RB cord-022526-j9kg00qf 4351 15 daily daily RB cord-022526-j9kg00qf 4351 16 ) ) -RRB- cord-022526-j9kg00qf 4351 17 to to TO cord-022526-j9kg00qf 4351 18 increase increase VB cord-022526-j9kg00qf 4351 19 the the DT cord-022526-j9kg00qf 4351 20 production production NN cord-022526-j9kg00qf 4351 21 of of IN cord-022526-j9kg00qf 4351 22 SCFAs scfa NNS cord-022526-j9kg00qf 4351 23 in in IN cord-022526-j9kg00qf 4351 24 the the DT cord-022526-j9kg00qf 4351 25 colon colon NN cord-022526-j9kg00qf 4351 26 . . . cord-022526-j9kg00qf 4352 1 Amylase amylase NN cord-022526-j9kg00qf 4352 2 - - HYPH cord-022526-j9kg00qf 4352 3 resistant resistant JJ cord-022526-j9kg00qf 4352 4 fermentable fermentable JJ cord-022526-j9kg00qf 4352 5 fiber fiber NN cord-022526-j9kg00qf 4352 6 such such JJ cord-022526-j9kg00qf 4352 7 as as IN cord-022526-j9kg00qf 4352 8 psyllium psyllium NN cord-022526-j9kg00qf 4352 9 is be VBZ cord-022526-j9kg00qf 4352 10 hydrolyzed hydrolyze VBN cord-022526-j9kg00qf 4352 11 by by IN cord-022526-j9kg00qf 4352 12 colonic colonic JJ cord-022526-j9kg00qf 4352 13 bacteria bacteria NNS cord-022526-j9kg00qf 4352 14 to to IN cord-022526-j9kg00qf 4352 15 SCFAs scfa NNS cord-022526-j9kg00qf 4352 16 such such JJ cord-022526-j9kg00qf 4352 17 as as IN cord-022526-j9kg00qf 4352 18 butyrate butyrate NN cord-022526-j9kg00qf 4352 19 , , , cord-022526-j9kg00qf 4352 20 which which WDT cord-022526-j9kg00qf 4352 21 represent represent VBP cord-022526-j9kg00qf 4352 22 a a DT cord-022526-j9kg00qf 4352 23 major major JJ cord-022526-j9kg00qf 4352 24 energy energy NN cord-022526-j9kg00qf 4352 25 source source NN cord-022526-j9kg00qf 4352 26 for for IN cord-022526-j9kg00qf 4352 27 colonocytes colonocyte NNS cord-022526-j9kg00qf 4352 28 . . . cord-022526-j9kg00qf 4353 1 Butyrate Butyrate NNP cord-022526-j9kg00qf 4353 2 and and CC cord-022526-j9kg00qf 4353 3 other other JJ cord-022526-j9kg00qf 4353 4 SCFAs scfa NNS cord-022526-j9kg00qf 4353 5 hasten hasten VBP cord-022526-j9kg00qf 4353 6 epithelial epithelial JJ cord-022526-j9kg00qf 4353 7 maturation maturation NN cord-022526-j9kg00qf 4353 8 and and CC cord-022526-j9kg00qf 4353 9 stimulate stimulate VB cord-022526-j9kg00qf 4353 10 salt salt NN cord-022526-j9kg00qf 4353 11 ( ( -LRB- cord-022526-j9kg00qf 4353 12 and and CC cord-022526-j9kg00qf 4353 13 thus thus RB cord-022526-j9kg00qf 4353 14 fluid fluid JJ cord-022526-j9kg00qf 4353 15 ) ) -RRB- cord-022526-j9kg00qf 4353 16 absorption absorption NN cord-022526-j9kg00qf 4353 17 in in IN cord-022526-j9kg00qf 4353 18 the the DT cord-022526-j9kg00qf 4353 19 colon colon NN cord-022526-j9kg00qf 4353 20 , , , cord-022526-j9kg00qf 4353 21 improve improve VB cord-022526-j9kg00qf 4353 22 the the DT cord-022526-j9kg00qf 4353 23 clinical clinical JJ cord-022526-j9kg00qf 4353 24 course course NN cord-022526-j9kg00qf 4353 25 of of IN cord-022526-j9kg00qf 4353 26 ulcerative ulcerative JJ cord-022526-j9kg00qf 4353 27 colitis colitis NN cord-022526-j9kg00qf 4353 28 , , , cord-022526-j9kg00qf 4353 29 and and CC cord-022526-j9kg00qf 4353 30 hasten hasten VB cord-022526-j9kg00qf 4353 31 colon colon NN cord-022526-j9kg00qf 4353 32 healing healing NN cord-022526-j9kg00qf 4353 33 . . . cord-022526-j9kg00qf 4354 1 226 226 CD cord-022526-j9kg00qf 4354 2 Psyllium psyllium NN cord-022526-j9kg00qf 4354 3 is be VBZ cord-022526-j9kg00qf 4354 4 itself -PRON- PRP cord-022526-j9kg00qf 4354 5 a a DT cord-022526-j9kg00qf 4354 6 source source NN cord-022526-j9kg00qf 4354 7 of of IN cord-022526-j9kg00qf 4354 8 butyrate butyrate NN cord-022526-j9kg00qf 4354 9 in in IN cord-022526-j9kg00qf 4354 10 the the DT cord-022526-j9kg00qf 4354 11 colon colon NN cord-022526-j9kg00qf 4354 12 and and CC cord-022526-j9kg00qf 4354 13 also also RB cord-022526-j9kg00qf 4354 14 promotes promote VBZ cord-022526-j9kg00qf 4354 15 the the DT cord-022526-j9kg00qf 4354 16 movement movement NN cord-022526-j9kg00qf 4354 17 of of IN cord-022526-j9kg00qf 4354 18 amylase amylase NN cord-022526-j9kg00qf 4354 19 sensitive sensitive JJ cord-022526-j9kg00qf 4354 20 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4354 21 into into IN cord-022526-j9kg00qf 4354 22 the the DT cord-022526-j9kg00qf 4354 23 distal distal JJ cord-022526-j9kg00qf 4354 24 colon colon NN cord-022526-j9kg00qf 4354 25 , , , cord-022526-j9kg00qf 4354 26 which which WDT cord-022526-j9kg00qf 4354 27 then then RB cord-022526-j9kg00qf 4354 28 are be VBP cord-022526-j9kg00qf 4354 29 fermented ferment VBN cord-022526-j9kg00qf 4354 30 to to IN cord-022526-j9kg00qf 4354 31 SCFAs scfa NNS cord-022526-j9kg00qf 4354 32 . . . cord-022526-j9kg00qf 4355 1 Thus thus RB cord-022526-j9kg00qf 4355 2 psyllium psyllium NN cord-022526-j9kg00qf 4355 3 is be VBZ cord-022526-j9kg00qf 4355 4 thought think VBN cord-022526-j9kg00qf 4355 5 to to TO cord-022526-j9kg00qf 4355 6 be be VB cord-022526-j9kg00qf 4355 7 clinically clinically RB cord-022526-j9kg00qf 4355 8 useful useful JJ cord-022526-j9kg00qf 4355 9 for for IN cord-022526-j9kg00qf 4355 10 promoting promote VBG cord-022526-j9kg00qf 4355 11 mucosal mucosal JJ cord-022526-j9kg00qf 4355 12 healing healing NN cord-022526-j9kg00qf 4355 13 in in IN cord-022526-j9kg00qf 4355 14 colitis colitis NN cord-022526-j9kg00qf 4355 15 . . . cord-022526-j9kg00qf 4356 1 Many many JJ cord-022526-j9kg00qf 4356 2 horses horse NNS cord-022526-j9kg00qf 4356 3 with with IN cord-022526-j9kg00qf 4356 4 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4356 5 or or CC cord-022526-j9kg00qf 4356 6 other other JJ cord-022526-j9kg00qf 4356 7 forms form NNS cord-022526-j9kg00qf 4356 8 of of IN cord-022526-j9kg00qf 4356 9 colitis colitis NN cord-022526-j9kg00qf 4356 10 have have VBP cord-022526-j9kg00qf 4356 11 mild mild JJ cord-022526-j9kg00qf 4356 12 to to IN cord-022526-j9kg00qf 4356 13 severe severe JJ cord-022526-j9kg00qf 4356 14 signs sign NNS cord-022526-j9kg00qf 4356 15 of of IN cord-022526-j9kg00qf 4356 16 abdominal abdominal JJ cord-022526-j9kg00qf 4356 17 pain pain NN cord-022526-j9kg00qf 4356 18 from from IN cord-022526-j9kg00qf 4356 19 gas gas NN cord-022526-j9kg00qf 4356 20 and and CC cord-022526-j9kg00qf 4356 21 fluid fluid JJ cord-022526-j9kg00qf 4356 22 distention distention NN cord-022526-j9kg00qf 4356 23 of of IN cord-022526-j9kg00qf 4356 24 the the DT cord-022526-j9kg00qf 4356 25 colon colon NN cord-022526-j9kg00qf 4356 26 , , , cord-022526-j9kg00qf 4356 27 colonic colonic JJ cord-022526-j9kg00qf 4356 28 ischemia ischemia NN cord-022526-j9kg00qf 4356 29 , , , cord-022526-j9kg00qf 4356 30 or or CC cord-022526-j9kg00qf 4356 31 infarction infarction NN cord-022526-j9kg00qf 4356 32 . . . cord-022526-j9kg00qf 4357 1 One one PRP cord-022526-j9kg00qf 4357 2 can can MD cord-022526-j9kg00qf 4357 3 accomplish accomplish VB cord-022526-j9kg00qf 4357 4 analgesia analgesia JJ cord-022526-j9kg00qf 4357 5 with with IN cord-022526-j9kg00qf 4357 6 NSAIDs nsaids JJ cord-022526-j9kg00qf 4357 7 such such JJ cord-022526-j9kg00qf 4357 8 as as IN cord-022526-j9kg00qf 4357 9 flunixin flunixin NNP cord-022526-j9kg00qf 4357 10 , , , cord-022526-j9kg00qf 4357 11 but but CC cord-022526-j9kg00qf 4357 12 the the DT cord-022526-j9kg00qf 4357 13 potential potential NN cord-022526-j9kg00qf 4357 14 for for IN cord-022526-j9kg00qf 4357 15 worsening worsen VBG cord-022526-j9kg00qf 4357 16 mucosal mucosal JJ cord-022526-j9kg00qf 4357 17 injury injury NN cord-022526-j9kg00qf 4357 18 or or CC cord-022526-j9kg00qf 4357 19 nephrotoxicity nephrotoxicity NN cord-022526-j9kg00qf 4357 20 may may MD cord-022526-j9kg00qf 4357 21 prevent prevent VB cord-022526-j9kg00qf 4357 22 the the DT cord-022526-j9kg00qf 4357 23 use use NN cord-022526-j9kg00qf 4357 24 of of IN cord-022526-j9kg00qf 4357 25 analgesic analgesic JJ cord-022526-j9kg00qf 4357 26 doses dose NNS cord-022526-j9kg00qf 4357 27 , , , cord-022526-j9kg00qf 4357 28 especially especially RB cord-022526-j9kg00qf 4357 29 in in IN cord-022526-j9kg00qf 4357 30 horses horse NNS cord-022526-j9kg00qf 4357 31 with with IN cord-022526-j9kg00qf 4357 32 suspected suspect VBN cord-022526-j9kg00qf 4357 33 NSAID NSAID NNP cord-022526-j9kg00qf 4357 34 toxicity toxicity NN cord-022526-j9kg00qf 4357 35 . . . cord-022526-j9kg00qf 4358 1 Newer new JJR cord-022526-j9kg00qf 4358 2 NSAIDs nsaid NNS cord-022526-j9kg00qf 4358 3 that that WDT cord-022526-j9kg00qf 4358 4 specifically specifically RB cord-022526-j9kg00qf 4358 5 target target VB cord-022526-j9kg00qf 4358 6 COX-2 COX-2 NNP cord-022526-j9kg00qf 4358 7 ( ( -LRB- cord-022526-j9kg00qf 4358 8 the the DT cord-022526-j9kg00qf 4358 9 inducible inducible JJ cord-022526-j9kg00qf 4358 10 COX COX NNP cord-022526-j9kg00qf 4358 11 ) ) -RRB- cord-022526-j9kg00qf 4358 12 but but CC cord-022526-j9kg00qf 4358 13 have have VBP cord-022526-j9kg00qf 4358 14 little little JJ cord-022526-j9kg00qf 4358 15 activity activity NN cord-022526-j9kg00qf 4358 16 against against IN cord-022526-j9kg00qf 4358 17 COX-1 cox-1 NN cord-022526-j9kg00qf 4358 18 ( ( -LRB- cord-022526-j9kg00qf 4358 19 the the DT cord-022526-j9kg00qf 4358 20 constitutive constitutive JJ cord-022526-j9kg00qf 4358 21 COX COX NNP cord-022526-j9kg00qf 4358 22 ) ) -RRB- cord-022526-j9kg00qf 4358 23 may may MD cord-022526-j9kg00qf 4358 24 be be VB cord-022526-j9kg00qf 4358 25 useful useful JJ cord-022526-j9kg00qf 4358 26 analgesics analgesic NNS cord-022526-j9kg00qf 4358 27 that that WDT cord-022526-j9kg00qf 4358 28 spare spare VBP cord-022526-j9kg00qf 4358 29 the the DT cord-022526-j9kg00qf 4358 30 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4358 31 mucosa mucosa NN cord-022526-j9kg00qf 4358 32 . . . cord-022526-j9kg00qf 4359 1 For for IN cord-022526-j9kg00qf 4359 2 example example NN cord-022526-j9kg00qf 4359 3 , , , cord-022526-j9kg00qf 4359 4 etodolac etodolac NNP cord-022526-j9kg00qf 4359 5 ( ( -LRB- cord-022526-j9kg00qf 4359 6 10 10 CD cord-022526-j9kg00qf 4359 7 to to TO cord-022526-j9kg00qf 4359 8 15 15 CD cord-022526-j9kg00qf 4359 9 mg mg NNP cord-022526-j9kg00qf 4359 10 / / SYM cord-022526-j9kg00qf 4359 11 kg kg CC cord-022526-j9kg00qf 4359 12 intravenously intravenously RB cord-022526-j9kg00qf 4359 13 or or CC cord-022526-j9kg00qf 4359 14 orally orally RB cord-022526-j9kg00qf 4359 15 once once IN cord-022526-j9kg00qf 4359 16 daily daily RB cord-022526-j9kg00qf 4359 17 ) ) -RRB- cord-022526-j9kg00qf 4359 18 has have VBZ cord-022526-j9kg00qf 4359 19 analgesic analgesic JJ cord-022526-j9kg00qf 4359 20 properties property NNS cord-022526-j9kg00qf 4359 21 in in IN cord-022526-j9kg00qf 4359 22 horses horse NNS cord-022526-j9kg00qf 4359 23 and and CC cord-022526-j9kg00qf 4359 24 may may MD cord-022526-j9kg00qf 4359 25 spare spare VB cord-022526-j9kg00qf 4359 26 the the DT cord-022526-j9kg00qf 4359 27 intestinal intestinal JJ cord-022526-j9kg00qf 4359 28 mucosa mucosa NN cord-022526-j9kg00qf 4359 29 from from IN cord-022526-j9kg00qf 4359 30 the the DT cord-022526-j9kg00qf 4359 31 detrimental detrimental JJ cord-022526-j9kg00qf 4359 32 effects effect NNS cord-022526-j9kg00qf 4359 33 associated associate VBN cord-022526-j9kg00qf 4359 34 with with IN cord-022526-j9kg00qf 4359 35 nonselective nonselective JJ cord-022526-j9kg00qf 4359 36 COX COX NNP cord-022526-j9kg00qf 4359 37 inhibitors inhibitor NNS cord-022526-j9kg00qf 4359 38 ( ( -LRB- cord-022526-j9kg00qf 4359 39 A.T. A.T. NNP cord-022526-j9kg00qf 4359 40 Blikslager Blikslager NNP cord-022526-j9kg00qf 4359 41 , , , cord-022526-j9kg00qf 4359 42 personal personal JJ cord-022526-j9kg00qf 4359 43 communication communication NN cord-022526-j9kg00qf 4359 44 , , , cord-022526-j9kg00qf 4359 45 2002 2002 CD cord-022526-j9kg00qf 4359 46 ) ) -RRB- cord-022526-j9kg00qf 4359 47 . . . cord-022526-j9kg00qf 4360 1 However however RB cord-022526-j9kg00qf 4360 2 , , , cord-022526-j9kg00qf 4360 3 the the DT cord-022526-j9kg00qf 4360 4 specificity specificity NN cord-022526-j9kg00qf 4360 5 for for IN cord-022526-j9kg00qf 4360 6 COX-2 COX-2 NNP cord-022526-j9kg00qf 4360 7 in in IN cord-022526-j9kg00qf 4360 8 horses horse NNS cord-022526-j9kg00qf 4360 9 is be VBZ cord-022526-j9kg00qf 4360 10 unproven unproven JJ cord-022526-j9kg00qf 4360 11 . . . cord-022526-j9kg00qf 4361 1 Thus thus RB cord-022526-j9kg00qf 4361 2 avoiding avoid VBG cord-022526-j9kg00qf 4361 3 the the DT cord-022526-j9kg00qf 4361 4 use use NN cord-022526-j9kg00qf 4361 5 of of IN cord-022526-j9kg00qf 4361 6 any any DT cord-022526-j9kg00qf 4361 7 NSAIDs nsaid NNS cord-022526-j9kg00qf 4361 8 in in IN cord-022526-j9kg00qf 4361 9 horses horse NNS cord-022526-j9kg00qf 4361 10 with with IN cord-022526-j9kg00qf 4361 11 RDC RDC NNP cord-022526-j9kg00qf 4361 12 or or CC cord-022526-j9kg00qf 4361 13 other other JJ cord-022526-j9kg00qf 4361 14 forms form NNS cord-022526-j9kg00qf 4361 15 of of IN cord-022526-j9kg00qf 4361 16 NSAID NSAID NNP cord-022526-j9kg00qf 4361 17 toxicity toxicity NN cord-022526-j9kg00qf 4361 18 is be VBZ cord-022526-j9kg00qf 4361 19 advisable advisable JJ cord-022526-j9kg00qf 4361 20 . . . cord-022526-j9kg00qf 4362 1 Xylazine xylazine NN cord-022526-j9kg00qf 4362 2 or or CC cord-022526-j9kg00qf 4362 3 detomidine detomidine NN cord-022526-j9kg00qf 4362 4 may may MD cord-022526-j9kg00qf 4362 5 provide provide VB cord-022526-j9kg00qf 4362 6 temporary temporary JJ cord-022526-j9kg00qf 4362 7 relief relief NN cord-022526-j9kg00qf 4362 8 of of IN cord-022526-j9kg00qf 4362 9 pain pain NN cord-022526-j9kg00qf 4362 10 . . . cord-022526-j9kg00qf 4363 1 Butorphanol Butorphanol NNP cord-022526-j9kg00qf 4363 2 is be VBZ cord-022526-j9kg00qf 4363 3 a a DT cord-022526-j9kg00qf 4363 4 useful useful JJ cord-022526-j9kg00qf 4363 5 analgesic analgesic NN cord-022526-j9kg00qf 4363 6 that that IN cord-022526-j9kg00qf 4363 7 one one PRP cord-022526-j9kg00qf 4363 8 can can MD cord-022526-j9kg00qf 4363 9 administer administer VB cord-022526-j9kg00qf 4363 10 intramuscularly intramuscularly RB cord-022526-j9kg00qf 4363 11 ( ( -LRB- cord-022526-j9kg00qf 4363 12 0.1 0.1 CD cord-022526-j9kg00qf 4363 13 mg mg NNP cord-022526-j9kg00qf 4363 14 / / SYM cord-022526-j9kg00qf 4363 15 kg kg NNP cord-022526-j9kg00qf 4363 16 every every DT cord-022526-j9kg00qf 4363 17 6 6 CD cord-022526-j9kg00qf 4363 18 hours hour NNS cord-022526-j9kg00qf 4363 19 ) ) -RRB- cord-022526-j9kg00qf 4363 20 or or CC cord-022526-j9kg00qf 4363 21 as as IN cord-022526-j9kg00qf 4363 22 a a DT cord-022526-j9kg00qf 4363 23 continuous continuous JJ cord-022526-j9kg00qf 4363 24 infusion infusion NN cord-022526-j9kg00qf 4363 25 . . . cord-022526-j9kg00qf 4364 1 An an DT cord-022526-j9kg00qf 4364 2 infusion infusion NN cord-022526-j9kg00qf 4364 3 of of IN cord-022526-j9kg00qf 4364 4 13.2 13.2 CD cord-022526-j9kg00qf 4364 5 µg µg NNP cord-022526-j9kg00qf 4364 6 / / SYM cord-022526-j9kg00qf 4364 7 kg kg NNP cord-022526-j9kg00qf 4364 8 / / SYM cord-022526-j9kg00qf 4364 9 hr hr NN cord-022526-j9kg00qf 4364 10 in in IN cord-022526-j9kg00qf 4364 11 isotonic isotonic JJ cord-022526-j9kg00qf 4364 12 crystalloid crystalloid NN cord-022526-j9kg00qf 4364 13 fluid fluid NN cord-022526-j9kg00qf 4364 14 such such JJ cord-022526-j9kg00qf 4364 15 as as IN cord-022526-j9kg00qf 4364 16 lactated lactate VBN cord-022526-j9kg00qf 4364 17 Ringer Ringer NNP cord-022526-j9kg00qf 4364 18 's 's POS cord-022526-j9kg00qf 4364 19 solution solution NN cord-022526-j9kg00qf 4364 20 has have VBZ cord-022526-j9kg00qf 4364 21 been be VBN cord-022526-j9kg00qf 4364 22 suggested suggest VBN cord-022526-j9kg00qf 4364 23 . . . cord-022526-j9kg00qf 4365 1 227 227 CD cord-022526-j9kg00qf 4365 2 Continuous continuous JJ cord-022526-j9kg00qf 4365 3 lidocaine lidocaine NN cord-022526-j9kg00qf 4365 4 infusions infusion NNS cord-022526-j9kg00qf 4365 5 ( ( -LRB- cord-022526-j9kg00qf 4365 6 1.3 1.3 CD cord-022526-j9kg00qf 4365 7 mg mg NNP cord-022526-j9kg00qf 4365 8 / / SYM cord-022526-j9kg00qf 4365 9 kg kg NN cord-022526-j9kg00qf 4365 10 intravenous intravenous JJ cord-022526-j9kg00qf 4365 11 loading loading NN cord-022526-j9kg00qf 4365 12 dose dose NN cord-022526-j9kg00qf 4365 13 administered administer VBN cord-022526-j9kg00qf 4365 14 slowly slowly RB cord-022526-j9kg00qf 4365 15 over over IN cord-022526-j9kg00qf 4365 16 5 5 CD cord-022526-j9kg00qf 4365 17 minutes minute NNS cord-022526-j9kg00qf 4365 18 and and CC cord-022526-j9kg00qf 4365 19 followed follow VBD cord-022526-j9kg00qf 4365 20 by by IN cord-022526-j9kg00qf 4365 21 3 3 CD cord-022526-j9kg00qf 4365 22 mg mg NNP cord-022526-j9kg00qf 4365 23 / / SYM cord-022526-j9kg00qf 4365 24 kg kg NNP cord-022526-j9kg00qf 4365 25 / / SYM cord-022526-j9kg00qf 4365 26 hr hr NN cord-022526-j9kg00qf 4365 27 infusion infusion NN cord-022526-j9kg00qf 4365 28 in in IN cord-022526-j9kg00qf 4365 29 isotonic isotonic JJ cord-022526-j9kg00qf 4365 30 crystalloid crystalloid NN cord-022526-j9kg00qf 4365 31 fluids fluid NNS cord-022526-j9kg00qf 4365 32 ) ) -RRB- cord-022526-j9kg00qf 4365 33 can can MD cord-022526-j9kg00qf 4365 34 provide provide VB cord-022526-j9kg00qf 4365 35 profound profound JJ cord-022526-j9kg00qf 4365 36 visceral visceral JJ cord-022526-j9kg00qf 4365 37 analgesia analgesia NN cord-022526-j9kg00qf 4365 38 and and CC cord-022526-j9kg00qf 4365 39 may may MD cord-022526-j9kg00qf 4365 40 have have VB cord-022526-j9kg00qf 4365 41 added add VBN cord-022526-j9kg00qf 4365 42 prokinetic prokinetic JJ cord-022526-j9kg00qf 4365 43 benefits benefit NNS cord-022526-j9kg00qf 4365 44 if if IN cord-022526-j9kg00qf 4365 45 ileus ileus NNP cord-022526-j9kg00qf 4365 46 is be VBZ cord-022526-j9kg00qf 4365 47 present present JJ cord-022526-j9kg00qf 4365 48 . . . cord-022526-j9kg00qf 4366 1 Broad broad JJ cord-022526-j9kg00qf 4366 2 - - HYPH cord-022526-j9kg00qf 4366 3 spectrum spectrum NN cord-022526-j9kg00qf 4366 4 antibiotic antibiotic JJ cord-022526-j9kg00qf 4366 5 treatment treatment NN cord-022526-j9kg00qf 4366 6 often often RB cord-022526-j9kg00qf 4366 7 is be VBZ cord-022526-j9kg00qf 4366 8 recommended recommend VBN cord-022526-j9kg00qf 4366 9 in in IN cord-022526-j9kg00qf 4366 10 neutropenic neutropenic JJ cord-022526-j9kg00qf 4366 11 horses horse NNS cord-022526-j9kg00qf 4366 12 or or CC cord-022526-j9kg00qf 4366 13 horses horse NNS cord-022526-j9kg00qf 4366 14 with with IN cord-022526-j9kg00qf 4366 15 signs sign NNS cord-022526-j9kg00qf 4366 16 of of IN cord-022526-j9kg00qf 4366 17 septicemia septicemia NN cord-022526-j9kg00qf 4366 18 . . . cord-022526-j9kg00qf 4367 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 4367 2 is be VBZ cord-022526-j9kg00qf 4367 3 associated associate VBN cord-022526-j9kg00qf 4367 4 with with IN cord-022526-j9kg00qf 4367 5 an an DT cord-022526-j9kg00qf 4367 6 increased increase VBN cord-022526-j9kg00qf 4367 7 risk risk NN cord-022526-j9kg00qf 4367 8 of of IN cord-022526-j9kg00qf 4367 9 septicemia septicemia NN cord-022526-j9kg00qf 4367 10 and and CC cord-022526-j9kg00qf 4367 11 septic septic JJ cord-022526-j9kg00qf 4367 12 complications complication NNS cord-022526-j9kg00qf 4367 13 such such JJ cord-022526-j9kg00qf 4367 14 as as IN cord-022526-j9kg00qf 4367 15 septic septic JJ cord-022526-j9kg00qf 4367 16 phlebitis phlebitis NN cord-022526-j9kg00qf 4367 17 and and CC cord-022526-j9kg00qf 4367 18 infection infection NN cord-022526-j9kg00qf 4367 19 of of IN cord-022526-j9kg00qf 4367 20 surgical surgical JJ cord-022526-j9kg00qf 4367 21 site site NN cord-022526-j9kg00qf 4367 22 . . . cord-022526-j9kg00qf 4368 1 1 1 LS cord-022526-j9kg00qf 4368 2 Septicemia septicemia NN cord-022526-j9kg00qf 4368 3 is be VBZ cord-022526-j9kg00qf 4368 4 a a DT cord-022526-j9kg00qf 4368 5 potentially potentially RB cord-022526-j9kg00qf 4368 6 life life NN cord-022526-j9kg00qf 4368 7 - - HYPH cord-022526-j9kg00qf 4368 8 threatening threaten VBG cord-022526-j9kg00qf 4368 9 complication complication NN cord-022526-j9kg00qf 4368 10 of of IN cord-022526-j9kg00qf 4368 11 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4368 12 and and CC cord-022526-j9kg00qf 4368 13 may may MD cord-022526-j9kg00qf 4368 14 be be VB cord-022526-j9kg00qf 4368 15 caused cause VBN cord-022526-j9kg00qf 4368 16 directly directly RB cord-022526-j9kg00qf 4368 17 by by IN cord-022526-j9kg00qf 4368 18 Salmonella Salmonella NNP cord-022526-j9kg00qf 4368 19 , , , cord-022526-j9kg00qf 4368 20 Clostridium Clostridium NNP cord-022526-j9kg00qf 4368 21 , , , cord-022526-j9kg00qf 4368 22 other other JJ cord-022526-j9kg00qf 4368 23 invasive invasive JJ cord-022526-j9kg00qf 4368 24 enteric enteric JJ cord-022526-j9kg00qf 4368 25 bacteria bacteria NNS cord-022526-j9kg00qf 4368 26 , , , cord-022526-j9kg00qf 4368 27 or or CC cord-022526-j9kg00qf 4368 28 indirectly indirectly RB cord-022526-j9kg00qf 4368 29 by by IN cord-022526-j9kg00qf 4368 30 toxic toxic JJ cord-022526-j9kg00qf 4368 31 injury injury NN cord-022526-j9kg00qf 4368 32 to to IN cord-022526-j9kg00qf 4368 33 the the DT cord-022526-j9kg00qf 4368 34 colonic colonic JJ cord-022526-j9kg00qf 4368 35 mucosa mucosa NN cord-022526-j9kg00qf 4368 36 that that WDT cord-022526-j9kg00qf 4368 37 breaks break VBZ cord-022526-j9kg00qf 4368 38 down down RP cord-022526-j9kg00qf 4368 39 the the DT cord-022526-j9kg00qf 4368 40 barrier barrier NN cord-022526-j9kg00qf 4368 41 to to IN cord-022526-j9kg00qf 4368 42 luminal luminal JJ cord-022526-j9kg00qf 4368 43 microbes microbe NNS cord-022526-j9kg00qf 4368 44 . . . cord-022526-j9kg00qf 4369 1 Neutropenia neutropenia NN cord-022526-j9kg00qf 4369 2 possibly possibly RB cord-022526-j9kg00qf 4369 3 may may MD cord-022526-j9kg00qf 4369 4 weaken weaken VB cord-022526-j9kg00qf 4369 5 host host NN cord-022526-j9kg00qf 4369 6 defenses defense NNS cord-022526-j9kg00qf 4369 7 enough enough JJ cord-022526-j9kg00qf 4369 8 to to TO cord-022526-j9kg00qf 4369 9 render render VB cord-022526-j9kg00qf 4369 10 horses horse NNS cord-022526-j9kg00qf 4369 11 susceptible susceptible JJ cord-022526-j9kg00qf 4369 12 to to IN cord-022526-j9kg00qf 4369 13 organisms organism NNS cord-022526-j9kg00qf 4369 14 that that WDT cord-022526-j9kg00qf 4369 15 breach breach VBP cord-022526-j9kg00qf 4369 16 the the DT cord-022526-j9kg00qf 4369 17 mucosal mucosal JJ cord-022526-j9kg00qf 4369 18 barrier barrier NN cord-022526-j9kg00qf 4369 19 . . . cord-022526-j9kg00qf 4370 1 Although although IN cord-022526-j9kg00qf 4370 2 most most JJS cord-022526-j9kg00qf 4370 3 attempts attempt NNS cord-022526-j9kg00qf 4370 4 to to IN cord-022526-j9kg00qf 4370 5 culture culture NN cord-022526-j9kg00qf 4370 6 bacteria bacteria NNS cord-022526-j9kg00qf 4370 7 from from IN cord-022526-j9kg00qf 4370 8 the the DT cord-022526-j9kg00qf 4370 9 blood blood NN cord-022526-j9kg00qf 4370 10 of of IN cord-022526-j9kg00qf 4370 11 adult adult NN cord-022526-j9kg00qf 4370 12 horses horse NNS cord-022526-j9kg00qf 4370 13 with with IN cord-022526-j9kg00qf 4370 14 colitis colitis NN cord-022526-j9kg00qf 4370 15 fail fail VBP cord-022526-j9kg00qf 4370 16 to to TO cord-022526-j9kg00qf 4370 17 isolate isolate VB cord-022526-j9kg00qf 4370 18 organisms organism NNS cord-022526-j9kg00qf 4370 19 , , , cord-022526-j9kg00qf 4370 20 no no DT cord-022526-j9kg00qf 4370 21 detailed detailed JJ cord-022526-j9kg00qf 4370 22 studies study NNS cord-022526-j9kg00qf 4370 23 have have VBP cord-022526-j9kg00qf 4370 24 been be VBN cord-022526-j9kg00qf 4370 25 undertaken undertake VBN cord-022526-j9kg00qf 4370 26 to to TO cord-022526-j9kg00qf 4370 27 determine determine VB cord-022526-j9kg00qf 4370 28 the the DT cord-022526-j9kg00qf 4370 29 prevalence prevalence NN cord-022526-j9kg00qf 4370 30 of of IN cord-022526-j9kg00qf 4370 31 bacteremia bacteremia NN cord-022526-j9kg00qf 4370 32 or or CC cord-022526-j9kg00qf 4370 33 septicemia septicemia NN cord-022526-j9kg00qf 4370 34 in in IN cord-022526-j9kg00qf 4370 35 these these DT cord-022526-j9kg00qf 4370 36 patients patient NNS cord-022526-j9kg00qf 4370 37 . . . cord-022526-j9kg00qf 4371 1 Disseminated disseminate VBN cord-022526-j9kg00qf 4371 2 aspergillosis aspergillosis NNP cord-022526-j9kg00qf 4371 3 has have VBZ cord-022526-j9kg00qf 4371 4 been be VBN cord-022526-j9kg00qf 4371 5 reported report VBN cord-022526-j9kg00qf 4371 6 in in IN cord-022526-j9kg00qf 4371 7 horses horse NNS cord-022526-j9kg00qf 4371 8 as as IN cord-022526-j9kg00qf 4371 9 a a DT cord-022526-j9kg00qf 4371 10 complication complication NN cord-022526-j9kg00qf 4371 11 of of IN cord-022526-j9kg00qf 4371 12 acute acute JJ cord-022526-j9kg00qf 4371 13 colitis colitis NN cord-022526-j9kg00qf 4371 14 , , , cord-022526-j9kg00qf 4371 15 demonstrating demonstrate VBG cord-022526-j9kg00qf 4371 16 the the DT cord-022526-j9kg00qf 4371 17 potential potential NN cord-022526-j9kg00qf 4371 18 for for IN cord-022526-j9kg00qf 4371 19 systemic systemic JJ cord-022526-j9kg00qf 4371 20 infections infection NNS cord-022526-j9kg00qf 4371 21 with with IN cord-022526-j9kg00qf 4371 22 rarely rarely RB cord-022526-j9kg00qf 4371 23 pathogenic pathogenic JJ cord-022526-j9kg00qf 4371 24 organisms organism NNS cord-022526-j9kg00qf 4371 25 stemming stem VBG cord-022526-j9kg00qf 4371 26 from from IN cord-022526-j9kg00qf 4371 27 colonic colonic JJ cord-022526-j9kg00qf 4371 28 mucosal mucosal JJ cord-022526-j9kg00qf 4371 29 injury injury NN cord-022526-j9kg00qf 4371 30 in in IN cord-022526-j9kg00qf 4371 31 the the DT cord-022526-j9kg00qf 4371 32 face face NN cord-022526-j9kg00qf 4371 33 of of IN cord-022526-j9kg00qf 4371 34 potential potential JJ cord-022526-j9kg00qf 4371 35 immunosuppression immunosuppression NN cord-022526-j9kg00qf 4371 36 from from IN cord-022526-j9kg00qf 4371 37 neutropenia neutropenia NN cord-022526-j9kg00qf 4371 38 . . . cord-022526-j9kg00qf 4372 1 228 228 CD cord-022526-j9kg00qf 4372 2 , , , cord-022526-j9kg00qf 4372 3 229 229 CD cord-022526-j9kg00qf 4372 4 Broad Broad NNP cord-022526-j9kg00qf 4372 5 - - HYPH cord-022526-j9kg00qf 4372 6 spectrum spectrum NN cord-022526-j9kg00qf 4372 7 antibiotics antibiotic NNS cord-022526-j9kg00qf 4372 8 lessen lessen VBP cord-022526-j9kg00qf 4372 9 septic septic JJ cord-022526-j9kg00qf 4372 10 complications complication NNS cord-022526-j9kg00qf 4372 11 in in IN cord-022526-j9kg00qf 4372 12 human human JJ cord-022526-j9kg00qf 4372 13 patients patient NNS cord-022526-j9kg00qf 4372 14 . . . cord-022526-j9kg00qf 4373 1 However however RB cord-022526-j9kg00qf 4373 2 , , , cord-022526-j9kg00qf 4373 3 evidence evidence NN cord-022526-j9kg00qf 4373 4 supporting support VBG cord-022526-j9kg00qf 4373 5 this this DT cord-022526-j9kg00qf 4373 6 principle principle NN cord-022526-j9kg00qf 4373 7 in in IN cord-022526-j9kg00qf 4373 8 horses horse NNS cord-022526-j9kg00qf 4373 9 with with IN cord-022526-j9kg00qf 4373 10 colitis colitis NN cord-022526-j9kg00qf 4373 11 is be VBZ cord-022526-j9kg00qf 4373 12 lacking lack VBG cord-022526-j9kg00qf 4373 13 . . . cord-022526-j9kg00qf 4374 1 Treatment treatment NN cord-022526-j9kg00qf 4374 2 with with IN cord-022526-j9kg00qf 4374 3 antibiotics antibiotic NNS cord-022526-j9kg00qf 4374 4 is be VBZ cord-022526-j9kg00qf 4374 5 controversial controversial JJ cord-022526-j9kg00qf 4374 6 in in IN cord-022526-j9kg00qf 4374 7 horses horse NNS cord-022526-j9kg00qf 4374 8 with with IN cord-022526-j9kg00qf 4374 9 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4374 10 and and CC cord-022526-j9kg00qf 4374 11 is be VBZ cord-022526-j9kg00qf 4374 12 not not RB cord-022526-j9kg00qf 4374 13 thought think VBN cord-022526-j9kg00qf 4374 14 to to TO cord-022526-j9kg00qf 4374 15 alter alter VB cord-022526-j9kg00qf 4374 16 the the DT cord-022526-j9kg00qf 4374 17 course course NN cord-022526-j9kg00qf 4374 18 of of IN cord-022526-j9kg00qf 4374 19 the the DT cord-022526-j9kg00qf 4374 20 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4374 21 . . . cord-022526-j9kg00qf 4375 1 Antibiotics antibiotic NNS cord-022526-j9kg00qf 4375 2 directly directly RB cord-022526-j9kg00qf 4375 3 targeted target VBN cord-022526-j9kg00qf 4375 4 at at IN cord-022526-j9kg00qf 4375 5 the the DT cord-022526-j9kg00qf 4375 6 Salmonella Salmonella NNP cord-022526-j9kg00qf 4375 7 are be VBP cord-022526-j9kg00qf 4375 8 reserved reserve VBN cord-022526-j9kg00qf 4375 9 for for IN cord-022526-j9kg00qf 4375 10 patients patient NNS cord-022526-j9kg00qf 4375 11 with with IN cord-022526-j9kg00qf 4375 12 the the DT cord-022526-j9kg00qf 4375 13 enteric enteric JJ cord-022526-j9kg00qf 4375 14 fever fever NN cord-022526-j9kg00qf 4375 15 ( ( -LRB- cord-022526-j9kg00qf 4375 16 septicemia septicemia NN cord-022526-j9kg00qf 4375 17 ) ) -RRB- cord-022526-j9kg00qf 4375 18 form form NN cord-022526-j9kg00qf 4375 19 of of IN cord-022526-j9kg00qf 4375 20 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4375 21 , , , cord-022526-j9kg00qf 4375 22 documented document VBN cord-022526-j9kg00qf 4375 23 with with IN cord-022526-j9kg00qf 4375 24 positive positive JJ cord-022526-j9kg00qf 4375 25 blood blood NN cord-022526-j9kg00qf 4375 26 cultures culture NNS cord-022526-j9kg00qf 4375 27 . . . cord-022526-j9kg00qf 4376 1 Lipid lipid NN cord-022526-j9kg00qf 4376 2 - - HYPH cord-022526-j9kg00qf 4376 3 soluble soluble JJ cord-022526-j9kg00qf 4376 4 antibiotics antibiotic NNS cord-022526-j9kg00qf 4376 5 are be VBP cord-022526-j9kg00qf 4376 6 suited suit VBN cord-022526-j9kg00qf 4376 7 ideally ideally RB cord-022526-j9kg00qf 4376 8 for for IN cord-022526-j9kg00qf 4376 9 Salmonella salmonella NN cord-022526-j9kg00qf 4376 10 infections infection NNS cord-022526-j9kg00qf 4376 11 , , , cord-022526-j9kg00qf 4376 12 because because IN cord-022526-j9kg00qf 4376 13 the the DT cord-022526-j9kg00qf 4376 14 bacteria bacteria NNS cord-022526-j9kg00qf 4376 15 persist persist VBP cord-022526-j9kg00qf 4376 16 intracellularly intracellularly RB cord-022526-j9kg00qf 4376 17 . . . cord-022526-j9kg00qf 4377 1 Trimethoprim Trimethoprim NNP cord-022526-j9kg00qf 4377 2 - - HYPH cord-022526-j9kg00qf 4377 3 sulfadiazine sulfadiazine NNP cord-022526-j9kg00qf 4377 4 or or CC cord-022526-j9kg00qf 4377 5 other other JJ cord-022526-j9kg00qf 4377 6 potentiated potentiated JJ cord-022526-j9kg00qf 4377 7 sulfa sulfa NN cord-022526-j9kg00qf 4377 8 drugs drug NNS cord-022526-j9kg00qf 4377 9 , , , cord-022526-j9kg00qf 4377 10 enrofloxacin enrofloxacin NNS cord-022526-j9kg00qf 4377 11 , , , cord-022526-j9kg00qf 4377 12 and and CC cord-022526-j9kg00qf 4377 13 chloramphenicol chloramphenicol NN cord-022526-j9kg00qf 4377 14 are be VBP cord-022526-j9kg00qf 4377 15 preferred prefer VBN cord-022526-j9kg00qf 4377 16 antibiotics antibiotic NNS cord-022526-j9kg00qf 4377 17 for for IN cord-022526-j9kg00qf 4377 18 the the DT cord-022526-j9kg00qf 4377 19 enteric enteric JJ cord-022526-j9kg00qf 4377 20 fever fever NN cord-022526-j9kg00qf 4377 21 form form NN cord-022526-j9kg00qf 4377 22 of of IN cord-022526-j9kg00qf 4377 23 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4377 24 for for IN cord-022526-j9kg00qf 4377 25 this this DT cord-022526-j9kg00qf 4377 26 reason reason NN cord-022526-j9kg00qf 4377 27 . . . cord-022526-j9kg00qf 4378 1 As as IN cord-022526-j9kg00qf 4378 2 with with IN cord-022526-j9kg00qf 4378 3 other other JJ cord-022526-j9kg00qf 4378 4 causes cause NNS cord-022526-j9kg00qf 4378 5 of of IN cord-022526-j9kg00qf 4378 6 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4378 7 , , , cord-022526-j9kg00qf 4378 8 the the DT cord-022526-j9kg00qf 4378 9 use use NN cord-022526-j9kg00qf 4378 10 of of IN cord-022526-j9kg00qf 4378 11 antibiotics antibiotic NNS cord-022526-j9kg00qf 4378 12 for for IN cord-022526-j9kg00qf 4378 13 equine equine JJ cord-022526-j9kg00qf 4378 14 monocytic monocytic JJ cord-022526-j9kg00qf 4378 15 ehrlichiosis ehrlichiosis NNP cord-022526-j9kg00qf 4378 16 is be VBZ cord-022526-j9kg00qf 4378 17 controversial controversial JJ cord-022526-j9kg00qf 4378 18 . . . cord-022526-j9kg00qf 4379 1 Fear fear NN cord-022526-j9kg00qf 4379 2 of of IN cord-022526-j9kg00qf 4379 3 inducing induce VBG cord-022526-j9kg00qf 4379 4 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4379 5 or or CC cord-022526-j9kg00qf 4379 6 other other JJ cord-022526-j9kg00qf 4379 7 forms form NNS cord-022526-j9kg00qf 4379 8 of of IN cord-022526-j9kg00qf 4379 9 antibiotic antibiotic NN cord-022526-j9kg00qf 4379 10 - - HYPH cord-022526-j9kg00qf 4379 11 induced induce VBN cord-022526-j9kg00qf 4379 12 diarrhea diarrhea NN cord-022526-j9kg00qf 4379 13 and and CC cord-022526-j9kg00qf 4379 14 the the DT cord-022526-j9kg00qf 4379 15 difficulty difficulty NN cord-022526-j9kg00qf 4379 16 of of IN cord-022526-j9kg00qf 4379 17 diagnosing diagnose VBG cord-022526-j9kg00qf 4379 18 the the DT cord-022526-j9kg00qf 4379 19 disease disease NN cord-022526-j9kg00qf 4379 20 early early RB cord-022526-j9kg00qf 4379 21 have have VBP cord-022526-j9kg00qf 4379 22 caused cause VBN cord-022526-j9kg00qf 4379 23 most most JJS cord-022526-j9kg00qf 4379 24 authors author NNS cord-022526-j9kg00qf 4379 25 to to TO cord-022526-j9kg00qf 4379 26 recommend recommend VB cord-022526-j9kg00qf 4379 27 judicious judicious JJ cord-022526-j9kg00qf 4379 28 use use NN cord-022526-j9kg00qf 4379 29 of of IN cord-022526-j9kg00qf 4379 30 antibiotics antibiotic NNS cord-022526-j9kg00qf 4379 31 . . . cord-022526-j9kg00qf 4380 1 49 49 CD cord-022526-j9kg00qf 4381 1 However however RB cord-022526-j9kg00qf 4381 2 , , , cord-022526-j9kg00qf 4381 3 in in IN cord-022526-j9kg00qf 4381 4 patients patient NNS cord-022526-j9kg00qf 4381 5 with with IN cord-022526-j9kg00qf 4381 6 a a DT cord-022526-j9kg00qf 4381 7 high high JJ cord-022526-j9kg00qf 4381 8 suspicion suspicion NN cord-022526-j9kg00qf 4381 9 of of IN cord-022526-j9kg00qf 4381 10 Neorickettsia Neorickettsia NNP cord-022526-j9kg00qf 4381 11 risticii risticii JJ cord-022526-j9kg00qf 4381 12 infection infection NN cord-022526-j9kg00qf 4381 13 , , , cord-022526-j9kg00qf 4381 14 treatment treatment NN cord-022526-j9kg00qf 4381 15 with with IN cord-022526-j9kg00qf 4381 16 antibiotics antibiotic NNS cord-022526-j9kg00qf 4381 17 often often RB cord-022526-j9kg00qf 4381 18 is be VBZ cord-022526-j9kg00qf 4381 19 indicated indicate VBN cord-022526-j9kg00qf 4381 20 before before IN cord-022526-j9kg00qf 4381 21 definitive definitive JJ cord-022526-j9kg00qf 4381 22 diagnosis diagnosis NN cord-022526-j9kg00qf 4381 23 . . . cord-022526-j9kg00qf 4382 1 Lipid lipid NN cord-022526-j9kg00qf 4382 2 - - HYPH cord-022526-j9kg00qf 4382 3 soluble soluble JJ cord-022526-j9kg00qf 4382 4 drugs drug NNS cord-022526-j9kg00qf 4382 5 are be VBP cord-022526-j9kg00qf 4382 6 desirable desirable JJ cord-022526-j9kg00qf 4382 7 because because IN cord-022526-j9kg00qf 4382 8 the the DT cord-022526-j9kg00qf 4382 9 organism organism NN cord-022526-j9kg00qf 4382 10 can can MD cord-022526-j9kg00qf 4382 11 live live VB cord-022526-j9kg00qf 4382 12 within within IN cord-022526-j9kg00qf 4382 13 cells cell NNS cord-022526-j9kg00qf 4382 14 . . . cord-022526-j9kg00qf 4383 1 Oxytetracycline Oxytetracycline NNP cord-022526-j9kg00qf 4383 2 ( ( -LRB- cord-022526-j9kg00qf 4383 3 6.6 6.6 CD cord-022526-j9kg00qf 4383 4 mg mg NNP cord-022526-j9kg00qf 4383 5 / / SYM cord-022526-j9kg00qf 4383 6 kg kg XX cord-022526-j9kg00qf 4383 7 intravenously intravenously RB cord-022526-j9kg00qf 4383 8 every every DT cord-022526-j9kg00qf 4383 9 24 24 CD cord-022526-j9kg00qf 4383 10 hours hour NNS cord-022526-j9kg00qf 4383 11 ) ) -RRB- cord-022526-j9kg00qf 4383 12 , , , cord-022526-j9kg00qf 4383 13 doxycycline doxycycline NNP cord-022526-j9kg00qf 4383 14 ( ( -LRB- cord-022526-j9kg00qf 4383 15 10 10 CD cord-022526-j9kg00qf 4383 16 mg mg NNP cord-022526-j9kg00qf 4383 17 / / SYM cord-022526-j9kg00qf 4383 18 kg kg CC cord-022526-j9kg00qf 4383 19 orally orally RB cord-022526-j9kg00qf 4383 20 every every DT cord-022526-j9kg00qf 4383 21 12 12 CD cord-022526-j9kg00qf 4383 22 hours hour NNS cord-022526-j9kg00qf 4383 23 ) ) -RRB- cord-022526-j9kg00qf 4383 24 , , , cord-022526-j9kg00qf 4383 25 trimethoprim trimethoprim NNP cord-022526-j9kg00qf 4383 26 - - HYPH cord-022526-j9kg00qf 4383 27 sulfadiazine sulfadiazine NNP cord-022526-j9kg00qf 4384 1 ( ( -LRB- cord-022526-j9kg00qf 4384 2 5 5 CD cord-022526-j9kg00qf 4384 3 mg mg NNP cord-022526-j9kg00qf 4384 4 / / SYM cord-022526-j9kg00qf 4384 5 kg kg NNP cord-022526-j9kg00qf 4384 6 trimethoprim trimethoprim NNP cord-022526-j9kg00qf 4384 7 orally orally RB cord-022526-j9kg00qf 4384 8 or or CC cord-022526-j9kg00qf 4384 9 intravenously intravenously RB cord-022526-j9kg00qf 4384 10 every every DT cord-022526-j9kg00qf 4384 11 8 8 CD cord-022526-j9kg00qf 4384 12 to to TO cord-022526-j9kg00qf 4384 13 12 12 CD cord-022526-j9kg00qf 4384 14 hours hour NNS cord-022526-j9kg00qf 4384 15 and and CC cord-022526-j9kg00qf 4384 16 25 25 CD cord-022526-j9kg00qf 4384 17 mg mg NNP cord-022526-j9kg00qf 4384 18 / / SYM cord-022526-j9kg00qf 4384 19 kg kg NN cord-022526-j9kg00qf 4384 20 sulfadiazine sulfadiazine NNP cord-022526-j9kg00qf 4384 21 every every DT cord-022526-j9kg00qf 4384 22 8 8 CD cord-022526-j9kg00qf 4384 23 to to TO cord-022526-j9kg00qf 4384 24 12 12 CD cord-022526-j9kg00qf 4384 25 hours hour NNS cord-022526-j9kg00qf 4384 26 ) ) -RRB- cord-022526-j9kg00qf 4384 27 , , , cord-022526-j9kg00qf 4384 28 or or CC cord-022526-j9kg00qf 4384 29 erythromycinrifampin erythromycinrifampin NNP cord-022526-j9kg00qf 4384 30 ( ( -LRB- cord-022526-j9kg00qf 4384 31 30 30 CD cord-022526-j9kg00qf 4384 32 mg mg NNP cord-022526-j9kg00qf 4384 33 / / SYM cord-022526-j9kg00qf 4384 34 kg kg NNS cord-022526-j9kg00qf 4384 35 and and CC cord-022526-j9kg00qf 4384 36 5 5 CD cord-022526-j9kg00qf 4384 37 mg mg NNP cord-022526-j9kg00qf 4384 38 / / SYM cord-022526-j9kg00qf 4384 39 kg kg NNS cord-022526-j9kg00qf 4384 40 , , , cord-022526-j9kg00qf 4384 41 respectively respectively RB cord-022526-j9kg00qf 4384 42 , , , cord-022526-j9kg00qf 4384 43 orally orally RB cord-022526-j9kg00qf 4384 44 every every DT cord-022526-j9kg00qf 4384 45 12 12 CD cord-022526-j9kg00qf 4384 46 hours hour NNS cord-022526-j9kg00qf 4384 47 ) ) -RRB- cord-022526-j9kg00qf 4384 48 have have VBP cord-022526-j9kg00qf 4384 49 been be VBN cord-022526-j9kg00qf 4384 50 used use VBN cord-022526-j9kg00qf 4384 51 effectively effectively RB cord-022526-j9kg00qf 4384 52 to to TO cord-022526-j9kg00qf 4384 53 treat treat VB cord-022526-j9kg00qf 4384 54 clinical clinical JJ cord-022526-j9kg00qf 4384 55 cases case NNS cord-022526-j9kg00qf 4384 56 . . . cord-022526-j9kg00qf 4385 1 49 49 CD cord-022526-j9kg00qf 4385 2 , , , cord-022526-j9kg00qf 4385 3 [ [ -LRB- cord-022526-j9kg00qf 4385 4 230 230 CD cord-022526-j9kg00qf 4385 5 ] ] -RRB- cord-022526-j9kg00qf 4385 6 [ [ -LRB- cord-022526-j9kg00qf 4385 7 231 231 CD cord-022526-j9kg00qf 4385 8 ] ] -RRB- cord-022526-j9kg00qf 4385 9 [ [ -LRB- cord-022526-j9kg00qf 4385 10 232 232 CD cord-022526-j9kg00qf 4385 11 ] ] -RRB- cord-022526-j9kg00qf 4386 1 The the DT cord-022526-j9kg00qf 4386 2 tetracyclines tetracycline NNS cord-022526-j9kg00qf 4386 3 appear appear VBP cord-022526-j9kg00qf 4386 4 to to TO cord-022526-j9kg00qf 4386 5 be be VB cord-022526-j9kg00qf 4386 6 the the DT cord-022526-j9kg00qf 4386 7 most most RBS cord-022526-j9kg00qf 4386 8 effective effective JJ cord-022526-j9kg00qf 4386 9 antibiotics antibiotic NNS cord-022526-j9kg00qf 4386 10 for for IN cord-022526-j9kg00qf 4386 11 treatment treatment NN cord-022526-j9kg00qf 4386 12 of of IN cord-022526-j9kg00qf 4386 13 Potomac Potomac NNP cord-022526-j9kg00qf 4386 14 horse horse NN cord-022526-j9kg00qf 4386 15 fever fever NN cord-022526-j9kg00qf 4386 16 . . . cord-022526-j9kg00qf 4387 1 Treatment treatment NN cord-022526-j9kg00qf 4387 2 is be VBZ cord-022526-j9kg00qf 4387 3 most most RBS cord-022526-j9kg00qf 4387 4 successful successful JJ cord-022526-j9kg00qf 4387 5 if if IN cord-022526-j9kg00qf 4387 6 initiated initiate VBN cord-022526-j9kg00qf 4387 7 before before IN cord-022526-j9kg00qf 4387 8 the the DT cord-022526-j9kg00qf 4387 9 onset onset NN cord-022526-j9kg00qf 4387 10 of of IN cord-022526-j9kg00qf 4387 11 diarrhea diarrhea NN cord-022526-j9kg00qf 4387 12 . . . cord-022526-j9kg00qf 4388 1 49 49 CD cord-022526-j9kg00qf 4388 2 , , , cord-022526-j9kg00qf 4388 3 231 231 CD cord-022526-j9kg00qf 4388 4 Clostridiosis Clostridiosis NNP cord-022526-j9kg00qf 4388 5 If if IN cord-022526-j9kg00qf 4388 6 one one PRP cord-022526-j9kg00qf 4388 7 has have VBZ cord-022526-j9kg00qf 4388 8 administered administer VBN cord-022526-j9kg00qf 4388 9 antibiotics antibiotic NNS cord-022526-j9kg00qf 4388 10 since since IN cord-022526-j9kg00qf 4388 11 the the DT cord-022526-j9kg00qf 4388 12 onset onset NN cord-022526-j9kg00qf 4388 13 of of IN cord-022526-j9kg00qf 4388 14 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4388 15 , , , cord-022526-j9kg00qf 4388 16 one one PRP cord-022526-j9kg00qf 4388 17 should should MD cord-022526-j9kg00qf 4388 18 discontinue discontinue VB cord-022526-j9kg00qf 4388 19 administration administration NN cord-022526-j9kg00qf 4388 20 as as RB cord-022526-j9kg00qf 4388 21 soon soon RB cord-022526-j9kg00qf 4388 22 as as IN cord-022526-j9kg00qf 4388 23 possible possible JJ cord-022526-j9kg00qf 4388 24 . . . cord-022526-j9kg00qf 4389 1 Specific specific JJ cord-022526-j9kg00qf 4389 2 treatment treatment NN cord-022526-j9kg00qf 4389 3 with with IN cord-022526-j9kg00qf 4389 4 metronidazole metronidazole NNP cord-022526-j9kg00qf 4389 5 ( ( -LRB- cord-022526-j9kg00qf 4389 6 15 15 CD cord-022526-j9kg00qf 4389 7 to to TO cord-022526-j9kg00qf 4389 8 25 25 CD cord-022526-j9kg00qf 4389 9 mg mg NNP cord-022526-j9kg00qf 4389 10 / / SYM cord-022526-j9kg00qf 4389 11 kg kg CC cord-022526-j9kg00qf 4389 12 orally orally RB cord-022526-j9kg00qf 4389 13 every every DT cord-022526-j9kg00qf 4389 14 8 8 CD cord-022526-j9kg00qf 4389 15 hours hour NNS cord-022526-j9kg00qf 4389 16 ) ) -RRB- cord-022526-j9kg00qf 4389 17 is be VBZ cord-022526-j9kg00qf 4389 18 effective effective JJ cord-022526-j9kg00qf 4389 19 for for IN cord-022526-j9kg00qf 4389 20 treating treat VBG cord-022526-j9kg00qf 4389 21 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4389 22 in in IN cord-022526-j9kg00qf 4389 23 human human JJ cord-022526-j9kg00qf 4389 24 beings being NNS cord-022526-j9kg00qf 4389 25 and and CC cord-022526-j9kg00qf 4389 26 appears appear VBZ cord-022526-j9kg00qf 4389 27 to to TO cord-022526-j9kg00qf 4389 28 be be VB cord-022526-j9kg00qf 4389 29 effective effective JJ cord-022526-j9kg00qf 4389 30 in in IN cord-022526-j9kg00qf 4389 31 horses horse NNS cord-022526-j9kg00qf 4389 32 . . . cord-022526-j9kg00qf 4390 1 83 83 CD cord-022526-j9kg00qf 4390 2 , , , cord-022526-j9kg00qf 4390 3 233 233 CD cord-022526-j9kg00qf 4390 4 Metronidazole Metronidazole NNP cord-022526-j9kg00qf 4390 5 resistance resistance NN cord-022526-j9kg00qf 4390 6 in in IN cord-022526-j9kg00qf 4390 7 clinical clinical JJ cord-022526-j9kg00qf 4390 8 isolates isolate NNS cord-022526-j9kg00qf 4390 9 of of IN cord-022526-j9kg00qf 4390 10 Clostridium clostridium NN cord-022526-j9kg00qf 4390 11 difficile difficile NN cord-022526-j9kg00qf 4390 12 has have VBZ cord-022526-j9kg00qf 4390 13 been be VBN cord-022526-j9kg00qf 4390 14 reported report VBN cord-022526-j9kg00qf 4390 15 in in IN cord-022526-j9kg00qf 4390 16 one one CD cord-022526-j9kg00qf 4390 17 outbreak outbreak NN cord-022526-j9kg00qf 4390 18 but but CC cord-022526-j9kg00qf 4390 19 appears appear VBZ cord-022526-j9kg00qf 4390 20 to to TO cord-022526-j9kg00qf 4390 21 be be VB cord-022526-j9kg00qf 4390 22 rare rare JJ cord-022526-j9kg00qf 4390 23 in in IN cord-022526-j9kg00qf 4390 24 most most JJS cord-022526-j9kg00qf 4390 25 human human JJ cord-022526-j9kg00qf 4390 26 and and CC cord-022526-j9kg00qf 4390 27 equine equine JJ cord-022526-j9kg00qf 4390 28 cases case NNS cord-022526-j9kg00qf 4390 29 . . . cord-022526-j9kg00qf 4391 1 234 234 CD cord-022526-j9kg00qf 4391 2 Metronidazole Metronidazole NNP cord-022526-j9kg00qf 4391 3 - - HYPH cord-022526-j9kg00qf 4391 4 resistant resistant JJ cord-022526-j9kg00qf 4391 5 isolates isolate NNS cord-022526-j9kg00qf 4391 6 were be VBD cord-022526-j9kg00qf 4391 7 sensitive sensitive JJ cord-022526-j9kg00qf 4391 8 to to IN cord-022526-j9kg00qf 4391 9 vancomycin vancomycin NN cord-022526-j9kg00qf 4391 10 , , , cord-022526-j9kg00qf 4391 11 which which WDT cord-022526-j9kg00qf 4391 12 may may MD cord-022526-j9kg00qf 4391 13 be be VB cord-022526-j9kg00qf 4391 14 effective effective JJ cord-022526-j9kg00qf 4391 15 for for IN cord-022526-j9kg00qf 4391 16 treating treat VBG cord-022526-j9kg00qf 4391 17 clinical clinical JJ cord-022526-j9kg00qf 4391 18 cases case NNS cord-022526-j9kg00qf 4391 19 if if IN cord-022526-j9kg00qf 4391 20 one one CD cord-022526-j9kg00qf 4391 21 suspects suspect NNS cord-022526-j9kg00qf 4391 22 metronidazole metronidazole VBP cord-022526-j9kg00qf 4391 23 resistance resistance NN cord-022526-j9kg00qf 4391 24 . . . cord-022526-j9kg00qf 4392 1 However however RB cord-022526-j9kg00qf 4392 2 , , , cord-022526-j9kg00qf 4392 3 metronidazole metronidazole NNP cord-022526-j9kg00qf 4392 4 remains remain VBZ cord-022526-j9kg00qf 4392 5 the the DT cord-022526-j9kg00qf 4392 6 treatment treatment NN cord-022526-j9kg00qf 4392 7 of of IN cord-022526-j9kg00qf 4392 8 choice choice NN cord-022526-j9kg00qf 4392 9 . . . cord-022526-j9kg00qf 4393 1 Some some DT cord-022526-j9kg00qf 4393 2 authors author NNS cord-022526-j9kg00qf 4393 3 describe describe VBP cord-022526-j9kg00qf 4393 4 the the DT cord-022526-j9kg00qf 4393 5 off off JJ cord-022526-j9kg00qf 4393 6 - - HYPH cord-022526-j9kg00qf 4393 7 label label NN cord-022526-j9kg00qf 4393 8 use use NN cord-022526-j9kg00qf 4393 9 of of IN cord-022526-j9kg00qf 4393 10 C. C. NNP cord-022526-j9kg00qf 4393 11 perfringens perfringens NN cord-022526-j9kg00qf 4393 12 type type NN cord-022526-j9kg00qf 4393 13 C c NN cord-022526-j9kg00qf 4393 14 antitoxin antitoxin NN cord-022526-j9kg00qf 4393 15 in in IN cord-022526-j9kg00qf 4393 16 cases case NNS cord-022526-j9kg00qf 4393 17 of of IN cord-022526-j9kg00qf 4393 18 neonatal neonatal JJ cord-022526-j9kg00qf 4393 19 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4393 20 , , , cord-022526-j9kg00qf 4393 21 described describe VBN cord-022526-j9kg00qf 4393 22 in in IN cord-022526-j9kg00qf 4393 23 more more JJR cord-022526-j9kg00qf 4393 24 detail detail NN cord-022526-j9kg00qf 4393 25 elsewhere elsewhere RB cord-022526-j9kg00qf 4393 26 . . . cord-022526-j9kg00qf 4394 1 235 235 CD cord-022526-j9kg00qf 4394 2 Antitoxin antitoxin NN cord-022526-j9kg00qf 4394 3 preparations preparation NNS cord-022526-j9kg00qf 4394 4 generally generally RB cord-022526-j9kg00qf 4394 5 are be VBP cord-022526-j9kg00qf 4394 6 not not RB cord-022526-j9kg00qf 4394 7 advocated advocate VBN cord-022526-j9kg00qf 4394 8 for for IN cord-022526-j9kg00qf 4394 9 use use NN cord-022526-j9kg00qf 4394 10 in in IN cord-022526-j9kg00qf 4394 11 adult adult NN cord-022526-j9kg00qf 4394 12 horses horse NNS cord-022526-j9kg00qf 4394 13 with with IN cord-022526-j9kg00qf 4394 14 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4394 15 . . . cord-022526-j9kg00qf 4395 1 Lawsonia Lawsonia NNP cord-022526-j9kg00qf 4395 2 intracellulare intracellulare NNP cord-022526-j9kg00qf 4395 3 is be VBZ cord-022526-j9kg00qf 4395 4 susceptible susceptible JJ cord-022526-j9kg00qf 4395 5 to to IN cord-022526-j9kg00qf 4395 6 a a DT cord-022526-j9kg00qf 4395 7 variety variety NN cord-022526-j9kg00qf 4395 8 of of IN cord-022526-j9kg00qf 4395 9 antibiotics antibiotic NNS cord-022526-j9kg00qf 4395 10 in in IN cord-022526-j9kg00qf 4395 11 vitro vitro FW cord-022526-j9kg00qf 4395 12 , , , cord-022526-j9kg00qf 4395 13 including include VBG cord-022526-j9kg00qf 4395 14 chlortetracycline chlortetracycline NN cord-022526-j9kg00qf 4395 15 , , , cord-022526-j9kg00qf 4395 16 erythromycin erythromycin NN cord-022526-j9kg00qf 4395 17 , , , cord-022526-j9kg00qf 4395 18 penicillin penicillin NN cord-022526-j9kg00qf 4395 19 , , , cord-022526-j9kg00qf 4395 20 difloxacin difloxacin NNS cord-022526-j9kg00qf 4395 21 , , , cord-022526-j9kg00qf 4395 22 and and CC cord-022526-j9kg00qf 4395 23 ampicillin ampicillin NN cord-022526-j9kg00qf 4395 24 . . . cord-022526-j9kg00qf 4396 1 236 236 CD cord-022526-j9kg00qf 4396 2 Lipid lipid NN cord-022526-j9kg00qf 4396 3 - - HYPH cord-022526-j9kg00qf 4396 4 soluble soluble JJ cord-022526-j9kg00qf 4396 5 antibiotics antibiotic NNS cord-022526-j9kg00qf 4396 6 with with IN cord-022526-j9kg00qf 4396 7 a a DT cord-022526-j9kg00qf 4396 8 large large JJ cord-022526-j9kg00qf 4396 9 volume volume NN cord-022526-j9kg00qf 4396 10 of of IN cord-022526-j9kg00qf 4396 11 distribution distribution NN cord-022526-j9kg00qf 4396 12 usually usually RB cord-022526-j9kg00qf 4396 13 are be VBP cord-022526-j9kg00qf 4396 14 chosen choose VBN cord-022526-j9kg00qf 4396 15 to to TO cord-022526-j9kg00qf 4396 16 treat treat VB cord-022526-j9kg00qf 4396 17 proliferative proliferative JJ cord-022526-j9kg00qf 4396 18 enteropathy enteropathy NN cord-022526-j9kg00qf 4396 19 because because IN cord-022526-j9kg00qf 4396 20 L. L. NNP cord-022526-j9kg00qf 4396 21 intracellulare intracellulare NNP cord-022526-j9kg00qf 4396 22 is be VBZ cord-022526-j9kg00qf 4396 23 an an DT cord-022526-j9kg00qf 4396 24 intracellular intracellular JJ cord-022526-j9kg00qf 4396 25 organism organism NN cord-022526-j9kg00qf 4396 26 . . . cord-022526-j9kg00qf 4397 1 Erythromycin Erythromycin NNP cord-022526-j9kg00qf 4397 2 estolate estolate NNP cord-022526-j9kg00qf 4397 3 ( ( -LRB- cord-022526-j9kg00qf 4397 4 15 15 CD cord-022526-j9kg00qf 4397 5 to to TO cord-022526-j9kg00qf 4397 6 25 25 CD cord-022526-j9kg00qf 4397 7 mg mg NN cord-022526-j9kg00qf 4398 1 /kg /kg NFP cord-022526-j9kg00qf 4398 2 orally orally RB cord-022526-j9kg00qf 4398 3 every every DT cord-022526-j9kg00qf 4398 4 6 6 CD cord-022526-j9kg00qf 4398 5 to to TO cord-022526-j9kg00qf 4398 6 8 8 CD cord-022526-j9kg00qf 4398 7 hours hour NNS cord-022526-j9kg00qf 4398 8 ) ) -RRB- cord-022526-j9kg00qf 4399 1 alone alone JJ cord-022526-j9kg00qf 4399 2 or or CC cord-022526-j9kg00qf 4399 3 with with IN cord-022526-j9kg00qf 4399 4 rifampin rifampin NNP cord-022526-j9kg00qf 4399 5 ( ( -LRB- cord-022526-j9kg00qf 4399 6 5 5 CD cord-022526-j9kg00qf 4399 7 mg mg NNP cord-022526-j9kg00qf 4399 8 / / SYM cord-022526-j9kg00qf 4399 9 kg kg XX cord-022526-j9kg00qf 4399 10 orally orally RB cord-022526-j9kg00qf 4399 11 every every DT cord-022526-j9kg00qf 4399 12 12 12 CD cord-022526-j9kg00qf 4399 13 hours hour NNS cord-022526-j9kg00qf 4399 14 ) ) -RRB- cord-022526-j9kg00qf 4400 1 is be VBZ cord-022526-j9kg00qf 4400 2 the the DT cord-022526-j9kg00qf 4400 3 most most RBS cord-022526-j9kg00qf 4400 4 commonly commonly RB cord-022526-j9kg00qf 4400 5 reported report VBN cord-022526-j9kg00qf 4400 6 efficacious efficacious JJ cord-022526-j9kg00qf 4400 7 treatment treatment NN cord-022526-j9kg00qf 4400 8 for for IN cord-022526-j9kg00qf 4400 9 proliferative proliferative JJ cord-022526-j9kg00qf 4400 10 enteropathy enteropathy NNP cord-022526-j9kg00qf 4400 11 . . . cord-022526-j9kg00qf 4401 1 Chloramphenicol Chloramphenicol NNP cord-022526-j9kg00qf 4401 2 ( ( -LRB- cord-022526-j9kg00qf 4401 3 50 50 CD cord-022526-j9kg00qf 4401 4 mg mg NNP cord-022526-j9kg00qf 4401 5 / / SYM cord-022526-j9kg00qf 4401 6 kg kg VBZ cord-022526-j9kg00qf 4401 7 orally orally RB cord-022526-j9kg00qf 4401 8 every every DT cord-022526-j9kg00qf 4401 9 6 6 CD cord-022526-j9kg00qf 4401 10 hours hour NNS cord-022526-j9kg00qf 4401 11 ) ) -RRB- cord-022526-j9kg00qf 4401 12 has have VBZ cord-022526-j9kg00qf 4401 13 also also RB cord-022526-j9kg00qf 4401 14 been be VBN cord-022526-j9kg00qf 4401 15 reported report VBN cord-022526-j9kg00qf 4401 16 to to TO cord-022526-j9kg00qf 4401 17 be be VB cord-022526-j9kg00qf 4401 18 effective effective JJ cord-022526-j9kg00qf 4401 19 if if IN cord-022526-j9kg00qf 4401 20 erythromycin erythromycin NN cord-022526-j9kg00qf 4401 21 worsens worsen VBZ cord-022526-j9kg00qf 4401 22 the the DT cord-022526-j9kg00qf 4401 23 diarrhea diarrhea NN cord-022526-j9kg00qf 4401 24 . . . cord-022526-j9kg00qf 4402 1 115 115 CD cord-022526-j9kg00qf 4402 2 Anecdotal anecdotal JJ cord-022526-j9kg00qf 4402 3 reports report NNS cord-022526-j9kg00qf 4402 4 suggest suggest VBP cord-022526-j9kg00qf 4402 5 that that IN cord-022526-j9kg00qf 4402 6 oxytetracycline oxytetracycline NNP cord-022526-j9kg00qf 4402 7 and and CC cord-022526-j9kg00qf 4402 8 doxycycline doxycycline NNP cord-022526-j9kg00qf 4402 9 also also RB cord-022526-j9kg00qf 4402 10 may may MD cord-022526-j9kg00qf 4402 11 be be VB cord-022526-j9kg00qf 4402 12 effective effective JJ cord-022526-j9kg00qf 4402 13 . . . cord-022526-j9kg00qf 4403 1 Supportive supportive JJ cord-022526-j9kg00qf 4403 2 care care NN cord-022526-j9kg00qf 4403 3 including include VBG cord-022526-j9kg00qf 4403 4 maintenance maintenance NN cord-022526-j9kg00qf 4403 5 of of IN cord-022526-j9kg00qf 4403 6 hydration hydration NN cord-022526-j9kg00qf 4403 7 and and CC cord-022526-j9kg00qf 4403 8 electrolyte electrolyte JJ cord-022526-j9kg00qf 4403 9 balance balance NN cord-022526-j9kg00qf 4403 10 and and CC cord-022526-j9kg00qf 4403 11 plasma plasma NN cord-022526-j9kg00qf 4403 12 or or CC cord-022526-j9kg00qf 4403 13 colloid colloid NN cord-022526-j9kg00qf 4403 14 administration administration NN cord-022526-j9kg00qf 4403 15 to to TO cord-022526-j9kg00qf 4403 16 increase increase VB cord-022526-j9kg00qf 4403 17 colloid colloid NN cord-022526-j9kg00qf 4403 18 oncotic oncotic JJ cord-022526-j9kg00qf 4403 19 pressure pressure NN cord-022526-j9kg00qf 4403 20 in in IN cord-022526-j9kg00qf 4403 21 hypoalbuminemic hypoalbuminemic NNP cord-022526-j9kg00qf 4403 22 patients patient NNS cord-022526-j9kg00qf 4403 23 is be VBZ cord-022526-j9kg00qf 4403 24 also also RB cord-022526-j9kg00qf 4403 25 indicated indicate VBN cord-022526-j9kg00qf 4403 26 . . . cord-022526-j9kg00qf 4404 1 One one PRP cord-022526-j9kg00qf 4404 2 should should MD cord-022526-j9kg00qf 4404 3 treat treat VB cord-022526-j9kg00qf 4404 4 affected affected JJ cord-022526-j9kg00qf 4404 5 foals foal NNS cord-022526-j9kg00qf 4404 6 until until IN cord-022526-j9kg00qf 4404 7 clinical clinical JJ cord-022526-j9kg00qf 4404 8 signs sign NNS cord-022526-j9kg00qf 4404 9 , , , cord-022526-j9kg00qf 4404 10 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 4404 11 , , , cord-022526-j9kg00qf 4404 12 and and CC cord-022526-j9kg00qf 4404 13 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 4404 14 evidence evidence NN cord-022526-j9kg00qf 4404 15 of of IN cord-022526-j9kg00qf 4404 16 intestinal intestinal JJ cord-022526-j9kg00qf 4404 17 thickening thickening NN cord-022526-j9kg00qf 4404 18 resolve resolve NN cord-022526-j9kg00qf 4404 19 . . . cord-022526-j9kg00qf 4405 1 The the DT cord-022526-j9kg00qf 4405 2 prognosis prognosis NN cord-022526-j9kg00qf 4405 3 depends depend VBZ cord-022526-j9kg00qf 4405 4 on on IN cord-022526-j9kg00qf 4405 5 the the DT cord-022526-j9kg00qf 4405 6 duration duration NN cord-022526-j9kg00qf 4405 7 of of IN cord-022526-j9kg00qf 4405 8 the the DT cord-022526-j9kg00qf 4405 9 disease disease NN cord-022526-j9kg00qf 4405 10 and and CC cord-022526-j9kg00qf 4405 11 the the DT cord-022526-j9kg00qf 4405 12 degree degree NN cord-022526-j9kg00qf 4405 13 of of IN cord-022526-j9kg00qf 4405 14 fibrosis fibrosis NN cord-022526-j9kg00qf 4405 15 and and CC cord-022526-j9kg00qf 4405 16 destruction destruction NN cord-022526-j9kg00qf 4405 17 of of IN cord-022526-j9kg00qf 4405 18 the the DT cord-022526-j9kg00qf 4405 19 intestinal intestinal JJ cord-022526-j9kg00qf 4405 20 architecture architecture NN cord-022526-j9kg00qf 4405 21 . . . cord-022526-j9kg00qf 4406 1 Hypercoagulability Hypercoagulability NNP cord-022526-j9kg00qf 4406 2 is be VBZ cord-022526-j9kg00qf 4406 3 a a DT cord-022526-j9kg00qf 4406 4 common common JJ cord-022526-j9kg00qf 4406 5 complication complication NN cord-022526-j9kg00qf 4406 6 of of IN cord-022526-j9kg00qf 4406 7 enterocolitis enterocolitis NN cord-022526-j9kg00qf 4406 8 , , , cord-022526-j9kg00qf 4406 9 associated associate VBN cord-022526-j9kg00qf 4406 10 with with IN cord-022526-j9kg00qf 4406 11 systemic systemic JJ cord-022526-j9kg00qf 4406 12 inflammation inflammation NN cord-022526-j9kg00qf 4406 13 from from IN cord-022526-j9kg00qf 4406 14 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4406 15 . . . cord-022526-j9kg00qf 4407 1 Administration administration NN cord-022526-j9kg00qf 4407 2 of of IN cord-022526-j9kg00qf 4407 3 heparin heparin NNP cord-022526-j9kg00qf 4407 4 ( ( -LRB- cord-022526-j9kg00qf 4407 5 20 20 CD cord-022526-j9kg00qf 4407 6 to to TO cord-022526-j9kg00qf 4407 7 80 80 CD cord-022526-j9kg00qf 4407 8 IU IU NNP cord-022526-j9kg00qf 4407 9 / / SYM cord-022526-j9kg00qf 4407 10 kg kg NNS cord-022526-j9kg00qf 4407 11 subcutaneously subcutaneously RB cord-022526-j9kg00qf 4407 12 or or CC cord-022526-j9kg00qf 4407 13 intravenously intravenously RB cord-022526-j9kg00qf 4407 14 every every DT cord-022526-j9kg00qf 4407 15 6 6 CD cord-022526-j9kg00qf 4407 16 to to TO cord-022526-j9kg00qf 4407 17 12 12 CD cord-022526-j9kg00qf 4407 18 hours hour NNS cord-022526-j9kg00qf 4407 19 ) ) -RRB- cord-022526-j9kg00qf 4407 20 may may MD cord-022526-j9kg00qf 4407 21 prevent prevent VB cord-022526-j9kg00qf 4407 22 thrombosis thrombosis NN cord-022526-j9kg00qf 4407 23 in in IN cord-022526-j9kg00qf 4407 24 these these DT cord-022526-j9kg00qf 4407 25 patients patient NNS cord-022526-j9kg00qf 4407 26 , , , cord-022526-j9kg00qf 4407 27 provided provide VBD cord-022526-j9kg00qf 4407 28 antithrombin antithrombin NN cord-022526-j9kg00qf 4407 29 III iii CD cord-022526-j9kg00qf 4407 30 concentrations concentration NNS cord-022526-j9kg00qf 4407 31 are be VBP cord-022526-j9kg00qf 4407 32 adequate adequate JJ cord-022526-j9kg00qf 4407 33 in in IN cord-022526-j9kg00qf 4407 34 the the DT cord-022526-j9kg00qf 4407 35 plasma plasma NN cord-022526-j9kg00qf 4407 36 . . . cord-022526-j9kg00qf 4408 1 Concentrated concentrated JJ cord-022526-j9kg00qf 4408 2 sources source NNS cord-022526-j9kg00qf 4408 3 of of IN cord-022526-j9kg00qf 4408 4 antithrombin antithrombin NN cord-022526-j9kg00qf 4408 5 III III NNP cord-022526-j9kg00qf 4408 6 are be VBP cord-022526-j9kg00qf 4408 7 not not RB cord-022526-j9kg00qf 4408 8 available available JJ cord-022526-j9kg00qf 4408 9 for for IN cord-022526-j9kg00qf 4408 10 use use NN cord-022526-j9kg00qf 4408 11 in in IN cord-022526-j9kg00qf 4408 12 horses horse NNS cord-022526-j9kg00qf 4408 13 , , , cord-022526-j9kg00qf 4408 14 but but CC cord-022526-j9kg00qf 4408 15 whole whole JJ cord-022526-j9kg00qf 4408 16 plasma plasma NN cord-022526-j9kg00qf 4408 17 may may MD cord-022526-j9kg00qf 4408 18 provide provide VB cord-022526-j9kg00qf 4408 19 an an DT cord-022526-j9kg00qf 4408 20 important important JJ cord-022526-j9kg00qf 4408 21 source source NN cord-022526-j9kg00qf 4408 22 . . . cord-022526-j9kg00qf 4409 1 Treatment treatment NN cord-022526-j9kg00qf 4409 2 with with IN cord-022526-j9kg00qf 4409 3 heparin heparin NN cord-022526-j9kg00qf 4409 4 is be VBZ cord-022526-j9kg00qf 4409 5 thought think VBN cord-022526-j9kg00qf 4409 6 to to TO cord-022526-j9kg00qf 4409 7 decrease decrease VB cord-022526-j9kg00qf 4409 8 thrombosis thrombosis NN cord-022526-j9kg00qf 4409 9 , , , cord-022526-j9kg00qf 4409 10 especially especially RB cord-022526-j9kg00qf 4409 11 of of IN cord-022526-j9kg00qf 4409 12 the the DT cord-022526-j9kg00qf 4409 13 jugular jugular NN cord-022526-j9kg00qf 4409 14 vein vein NN cord-022526-j9kg00qf 4409 15 , , , cord-022526-j9kg00qf 4409 16 a a DT cord-022526-j9kg00qf 4409 17 serious serious JJ cord-022526-j9kg00qf 4409 18 complication complication NN cord-022526-j9kg00qf 4409 19 of of IN cord-022526-j9kg00qf 4409 20 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4409 21 . . . cord-022526-j9kg00qf 4410 1 Low low JJ cord-022526-j9kg00qf 4410 2 - - HYPH cord-022526-j9kg00qf 4410 3 dose dose NN cord-022526-j9kg00qf 4410 4 aspirin aspirin NN cord-022526-j9kg00qf 4410 5 treatment treatment NN cord-022526-j9kg00qf 4410 6 ( ( -LRB- cord-022526-j9kg00qf 4410 7 15 15 CD cord-022526-j9kg00qf 4410 8 mg mg NNP cord-022526-j9kg00qf 4410 9 / / SYM cord-022526-j9kg00qf 4410 10 kg kg XX cord-022526-j9kg00qf 4410 11 orally orally RB cord-022526-j9kg00qf 4410 12 every every DT cord-022526-j9kg00qf 4410 13 24 24 CD cord-022526-j9kg00qf 4410 14 to to TO cord-022526-j9kg00qf 4410 15 48 48 CD cord-022526-j9kg00qf 4410 16 hours hour NNS cord-022526-j9kg00qf 4410 17 ) ) -RRB- cord-022526-j9kg00qf 4410 18 along along IN cord-022526-j9kg00qf 4410 19 with with IN cord-022526-j9kg00qf 4410 20 heparin heparin JJ cord-022526-j9kg00qf 4410 21 treatment treatment NN cord-022526-j9kg00qf 4410 22 may may MD cord-022526-j9kg00qf 4410 23 provide provide VB cord-022526-j9kg00qf 4410 24 added add VBN cord-022526-j9kg00qf 4410 25 benefit benefit NN cord-022526-j9kg00qf 4410 26 by by IN cord-022526-j9kg00qf 4410 27 irreversibly irreversibly RB cord-022526-j9kg00qf 4410 28 inhibiting inhibit VBG cord-022526-j9kg00qf 4410 29 platelet platelet NN cord-022526-j9kg00qf 4410 30 function function NN cord-022526-j9kg00qf 4410 31 . . . cord-022526-j9kg00qf 4411 1 237 237 CD cord-022526-j9kg00qf 4411 2 Heparin Heparin NNP cord-022526-j9kg00qf 4411 3 and and CC cord-022526-j9kg00qf 4411 4 aspirin aspirin NN cord-022526-j9kg00qf 4411 5 may may MD cord-022526-j9kg00qf 4411 6 have have VB cord-022526-j9kg00qf 4411 7 protective protective JJ cord-022526-j9kg00qf 4411 8 effects effect NNS cord-022526-j9kg00qf 4411 9 on on IN cord-022526-j9kg00qf 4411 10 the the DT cord-022526-j9kg00qf 4411 11 digital digital JJ cord-022526-j9kg00qf 4411 12 lamina lamina NN cord-022526-j9kg00qf 4411 13 . . . cord-022526-j9kg00qf 4412 1 237 237 CD cord-022526-j9kg00qf 4412 2 , , , cord-022526-j9kg00qf 4412 3 238 238 CD cord-022526-j9kg00qf 4412 4 Heparin Heparin NNP cord-022526-j9kg00qf 4412 5 also also RB cord-022526-j9kg00qf 4412 6 may may MD cord-022526-j9kg00qf 4412 7 enhance enhance VB cord-022526-j9kg00qf 4412 8 the the DT cord-022526-j9kg00qf 4412 9 phagocytic phagocytic JJ cord-022526-j9kg00qf 4412 10 activity activity NN cord-022526-j9kg00qf 4412 11 of of IN cord-022526-j9kg00qf 4412 12 the the DT cord-022526-j9kg00qf 4412 13 reticuloendothelial reticuloendothelial JJ cord-022526-j9kg00qf 4412 14 system system NN cord-022526-j9kg00qf 4412 15 by by IN cord-022526-j9kg00qf 4412 16 enhancing enhance VBG cord-022526-j9kg00qf 4412 17 the the DT cord-022526-j9kg00qf 4412 18 efficiency efficiency NN cord-022526-j9kg00qf 4412 19 of of IN cord-022526-j9kg00qf 4412 20 opsonins opsonin NNS cord-022526-j9kg00qf 4412 21 such such JJ cord-022526-j9kg00qf 4412 22 as as IN cord-022526-j9kg00qf 4412 23 fibronectin fibronectin NN cord-022526-j9kg00qf 4412 24 and and CC cord-022526-j9kg00qf 4412 25 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 4412 26 , , , cord-022526-j9kg00qf 4412 27 thereby thereby RB cord-022526-j9kg00qf 4412 28 stimulating stimulate VBG cord-022526-j9kg00qf 4412 29 phagocytosis phagocytosis NN cord-022526-j9kg00qf 4412 30 of of IN cord-022526-j9kg00qf 4412 31 products product NNS cord-022526-j9kg00qf 4412 32 of of IN cord-022526-j9kg00qf 4412 33 coagulation coagulation NN cord-022526-j9kg00qf 4412 34 and and CC cord-022526-j9kg00qf 4412 35 possibly possibly RB cord-022526-j9kg00qf 4412 36 other other JJ cord-022526-j9kg00qf 4412 37 particles particle NNS cord-022526-j9kg00qf 4412 38 , , , cord-022526-j9kg00qf 4412 39 including include VBG cord-022526-j9kg00qf 4412 40 bacteria bacteria NNS cord-022526-j9kg00qf 4412 41 . . . cord-022526-j9kg00qf 4413 1 239 239 CD cord-022526-j9kg00qf 4413 2 , , , cord-022526-j9kg00qf 4413 3 240 240 CD cord-022526-j9kg00qf 4413 4 _SP cord-022526-j9kg00qf 4413 5 Maintenance maintenance NN cord-022526-j9kg00qf 4413 6 of of IN cord-022526-j9kg00qf 4413 7 the the DT cord-022526-j9kg00qf 4413 8 bacterial bacterial JJ cord-022526-j9kg00qf 4413 9 flora flora NNS cord-022526-j9kg00qf 4413 10 and and CC cord-022526-j9kg00qf 4413 11 antagonism antagonism NN cord-022526-j9kg00qf 4413 12 of of IN cord-022526-j9kg00qf 4413 13 pathogenic pathogenic JJ cord-022526-j9kg00qf 4413 14 bacteria bacteria NNS cord-022526-j9kg00qf 4413 15 such such JJ cord-022526-j9kg00qf 4413 16 as as IN cord-022526-j9kg00qf 4413 17 Salmonella Salmonella NNP cord-022526-j9kg00qf 4413 18 in in IN cord-022526-j9kg00qf 4413 19 the the DT cord-022526-j9kg00qf 4413 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4413 21 tract tract NN cord-022526-j9kg00qf 4413 22 are be VBP cord-022526-j9kg00qf 4413 23 important important JJ cord-022526-j9kg00qf 4413 24 defense defense NN cord-022526-j9kg00qf 4413 25 mechanisms mechanism NNS cord-022526-j9kg00qf 4413 26 preventing prevent VBG cord-022526-j9kg00qf 4413 27 colonization colonization NN cord-022526-j9kg00qf 4413 28 by by IN cord-022526-j9kg00qf 4413 29 pathogenic pathogenic JJ cord-022526-j9kg00qf 4413 30 bacteria bacteria NNS cord-022526-j9kg00qf 4413 31 . . . cord-022526-j9kg00qf 4414 1 The the DT cord-022526-j9kg00qf 4414 2 use use NN cord-022526-j9kg00qf 4414 3 of of IN cord-022526-j9kg00qf 4414 4 probiotic probiotic JJ cord-022526-j9kg00qf 4414 5 preparations preparation NNS cord-022526-j9kg00qf 4414 6 containing contain VBG cord-022526-j9kg00qf 4414 7 beneficial beneficial JJ cord-022526-j9kg00qf 4414 8 bacteria bacteria NNS cord-022526-j9kg00qf 4414 9 has have VBZ cord-022526-j9kg00qf 4414 10 been be VBN cord-022526-j9kg00qf 4414 11 shown show VBN cord-022526-j9kg00qf 4414 12 to to TO cord-022526-j9kg00qf 4414 13 prevent prevent VB cord-022526-j9kg00qf 4414 14 colonization colonization NN cord-022526-j9kg00qf 4414 15 of of IN cord-022526-j9kg00qf 4414 16 pathogenic pathogenic JJ cord-022526-j9kg00qf 4414 17 bacteria bacteria NNS cord-022526-j9kg00qf 4414 18 , , , cord-022526-j9kg00qf 4414 19 including include VBG cord-022526-j9kg00qf 4414 20 Salmonella Salmonella NNP cord-022526-j9kg00qf 4414 21 , , , cord-022526-j9kg00qf 4414 22 in in IN cord-022526-j9kg00qf 4414 23 poultry poultry NN cord-022526-j9kg00qf 4414 24 . . . cord-022526-j9kg00qf 4415 1 241 241 CD cord-022526-j9kg00qf 4416 1 Little little JJ cord-022526-j9kg00qf 4416 2 work work NN cord-022526-j9kg00qf 4416 3 has have VBZ cord-022526-j9kg00qf 4416 4 been be VBN cord-022526-j9kg00qf 4416 5 done do VBN cord-022526-j9kg00qf 4416 6 to to TO cord-022526-j9kg00qf 4416 7 investigate investigate VB cord-022526-j9kg00qf 4416 8 the the DT cord-022526-j9kg00qf 4416 9 efficacy efficacy NN cord-022526-j9kg00qf 4416 10 of of IN cord-022526-j9kg00qf 4416 11 these these DT cord-022526-j9kg00qf 4416 12 products product NNS cord-022526-j9kg00qf 4416 13 in in IN cord-022526-j9kg00qf 4416 14 preventing prevent VBG cord-022526-j9kg00qf 4416 15 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4416 16 in in IN cord-022526-j9kg00qf 4416 17 horses horse NNS cord-022526-j9kg00qf 4416 18 , , , cord-022526-j9kg00qf 4416 19 but but CC cord-022526-j9kg00qf 4416 20 ongoing ongoing JJ cord-022526-j9kg00qf 4416 21 studies study NNS cord-022526-j9kg00qf 4416 22 may may MD cord-022526-j9kg00qf 4416 23 provide provide VB cord-022526-j9kg00qf 4416 24 important important JJ cord-022526-j9kg00qf 4416 25 information information NN cord-022526-j9kg00qf 4416 26 . . . cord-022526-j9kg00qf 4417 1 Probiotic probiotic JJ cord-022526-j9kg00qf 4417 2 and and CC cord-022526-j9kg00qf 4417 3 other other JJ cord-022526-j9kg00qf 4417 4 preparations preparation NNS cord-022526-j9kg00qf 4417 5 designed design VBN cord-022526-j9kg00qf 4417 6 to to TO cord-022526-j9kg00qf 4417 7 restore restore VB cord-022526-j9kg00qf 4417 8 normal normal JJ cord-022526-j9kg00qf 4417 9 flora flora NNS cord-022526-j9kg00qf 4417 10 to to IN cord-022526-j9kg00qf 4417 11 the the DT cord-022526-j9kg00qf 4417 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4417 13 tract tract NN cord-022526-j9kg00qf 4417 14 , , , cord-022526-j9kg00qf 4417 15 such such JJ cord-022526-j9kg00qf 4417 16 as as IN cord-022526-j9kg00qf 4417 17 fecal fecal JJ cord-022526-j9kg00qf 4417 18 suspensions suspension NNS cord-022526-j9kg00qf 4417 19 , , , cord-022526-j9kg00qf 4417 20 sour sour JJ cord-022526-j9kg00qf 4417 21 milk milk NN cord-022526-j9kg00qf 4417 22 , , , cord-022526-j9kg00qf 4417 23 and and CC cord-022526-j9kg00qf 4417 24 yogurt yogurt NN cord-022526-j9kg00qf 4417 25 , , , cord-022526-j9kg00qf 4417 26 have have VBP cord-022526-j9kg00qf 4417 27 been be VBN cord-022526-j9kg00qf 4417 28 used use VBN cord-022526-j9kg00qf 4417 29 clinically clinically RB cord-022526-j9kg00qf 4417 30 to to TO cord-022526-j9kg00qf 4417 31 shorten shorten VB cord-022526-j9kg00qf 4417 32 the the DT cord-022526-j9kg00qf 4417 33 course course NN cord-022526-j9kg00qf 4417 34 of of IN cord-022526-j9kg00qf 4417 35 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4417 36 , , , cord-022526-j9kg00qf 4417 37 with with IN cord-022526-j9kg00qf 4417 38 variable variable JJ cord-022526-j9kg00qf 4417 39 results result NNS cord-022526-j9kg00qf 4417 40 . . . cord-022526-j9kg00qf 4418 1 Therefore therefore RB cord-022526-j9kg00qf 4418 2 prevention prevention NN cord-022526-j9kg00qf 4418 3 of of IN cord-022526-j9kg00qf 4418 4 infection infection NN cord-022526-j9kg00qf 4418 5 by by IN cord-022526-j9kg00qf 4418 6 using use VBG cord-022526-j9kg00qf 4418 7 probiotic probiotic JJ cord-022526-j9kg00qf 4418 8 agents agent NNS cord-022526-j9kg00qf 4418 9 and and CC cord-022526-j9kg00qf 4418 10 other other JJ cord-022526-j9kg00qf 4418 11 means mean NNS cord-022526-j9kg00qf 4418 12 is be VBZ cord-022526-j9kg00qf 4418 13 important important JJ cord-022526-j9kg00qf 4418 14 . . . cord-022526-j9kg00qf 4419 1 Exposure exposure NN cord-022526-j9kg00qf 4419 2 of of IN cord-022526-j9kg00qf 4419 3 susceptible susceptible JJ cord-022526-j9kg00qf 4419 4 horses horse NNS cord-022526-j9kg00qf 4419 5 to to IN cord-022526-j9kg00qf 4419 6 Salmonella Salmonella NNP cord-022526-j9kg00qf 4419 7 should should MD cord-022526-j9kg00qf 4419 8 be be VB cord-022526-j9kg00qf 4419 9 avoided avoid VBN cord-022526-j9kg00qf 4419 10 , , , cord-022526-j9kg00qf 4419 11 but but CC cord-022526-j9kg00qf 4419 12 the the DT cord-022526-j9kg00qf 4419 13 task task NN cord-022526-j9kg00qf 4419 14 is be VBZ cord-022526-j9kg00qf 4419 15 difficult difficult JJ cord-022526-j9kg00qf 4419 16 , , , cord-022526-j9kg00qf 4419 17 especially especially RB cord-022526-j9kg00qf 4419 18 because because IN cord-022526-j9kg00qf 4419 19 asymptomatic asymptomatic JJ cord-022526-j9kg00qf 4419 20 infections infection NNS cord-022526-j9kg00qf 4419 21 are be VBP cord-022526-j9kg00qf 4419 22 common common JJ cord-022526-j9kg00qf 4419 23 and and CC cord-022526-j9kg00qf 4419 24 the the DT cord-022526-j9kg00qf 4419 25 bacteria bacteria NNS cord-022526-j9kg00qf 4419 26 are be VBP cord-022526-j9kg00qf 4419 27 ubiquitous ubiquitous JJ cord-022526-j9kg00qf 4419 28 in in IN cord-022526-j9kg00qf 4419 29 the the DT cord-022526-j9kg00qf 4419 30 environment environment NN cord-022526-j9kg00qf 4419 31 . . . cord-022526-j9kg00qf 4420 1 Prophylactic prophylactic JJ cord-022526-j9kg00qf 4420 2 use use NN cord-022526-j9kg00qf 4420 3 of of IN cord-022526-j9kg00qf 4420 4 probiotic probiotic JJ cord-022526-j9kg00qf 4420 5 preparations preparation NNS cord-022526-j9kg00qf 4420 6 , , , cord-022526-j9kg00qf 4420 7 judicious judicious JJ cord-022526-j9kg00qf 4420 8 use use NN cord-022526-j9kg00qf 4420 9 of of IN cord-022526-j9kg00qf 4420 10 antibiotics antibiotic NNS cord-022526-j9kg00qf 4420 11 in in IN cord-022526-j9kg00qf 4420 12 susceptible susceptible JJ cord-022526-j9kg00qf 4420 13 horses horse NNS cord-022526-j9kg00qf 4420 14 , , , cord-022526-j9kg00qf 4420 15 control control NN cord-022526-j9kg00qf 4420 16 of of IN cord-022526-j9kg00qf 4420 17 environmental environmental JJ cord-022526-j9kg00qf 4420 18 conditions condition NNS cord-022526-j9kg00qf 4420 19 such such JJ cord-022526-j9kg00qf 4420 20 as as IN cord-022526-j9kg00qf 4420 21 temperature temperature NN cord-022526-j9kg00qf 4420 22 , , , cord-022526-j9kg00qf 4420 23 and and CC cord-022526-j9kg00qf 4420 24 restricted restrict VBN cord-022526-j9kg00qf 4420 25 exposure exposure NN cord-022526-j9kg00qf 4420 26 to to IN cord-022526-j9kg00qf 4420 27 pathogenic pathogenic JJ cord-022526-j9kg00qf 4420 28 bacteria bacteria NNS cord-022526-j9kg00qf 4420 29 are be VBP cord-022526-j9kg00qf 4420 30 important important JJ cord-022526-j9kg00qf 4420 31 for for IN cord-022526-j9kg00qf 4420 32 control control NN cord-022526-j9kg00qf 4420 33 of of IN cord-022526-j9kg00qf 4420 34 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4420 35 . . . cord-022526-j9kg00qf 4421 1 Because because IN cord-022526-j9kg00qf 4421 2 altered alter VBN cord-022526-j9kg00qf 4421 3 large large JJ cord-022526-j9kg00qf 4421 4 intestinal intestinal JJ cord-022526-j9kg00qf 4421 5 flora flora NNS cord-022526-j9kg00qf 4421 6 appears appear VBZ cord-022526-j9kg00qf 4421 7 to to TO cord-022526-j9kg00qf 4421 8 play play VB cord-022526-j9kg00qf 4421 9 an an DT cord-022526-j9kg00qf 4421 10 important important JJ cord-022526-j9kg00qf 4421 11 role role NN cord-022526-j9kg00qf 4421 12 in in IN cord-022526-j9kg00qf 4421 13 the the DT cord-022526-j9kg00qf 4421 14 pathogenesis pathogenesis NN cord-022526-j9kg00qf 4421 15 of of IN cord-022526-j9kg00qf 4421 16 equine equine JJ cord-022526-j9kg00qf 4421 17 intestinal intestinal JJ cord-022526-j9kg00qf 4421 18 clostridiosis clostridiosis NN cord-022526-j9kg00qf 4421 19 or or CC cord-022526-j9kg00qf 4421 20 any any DT cord-022526-j9kg00qf 4421 21 antibiotic antibiotic JJ cord-022526-j9kg00qf 4421 22 - - HYPH cord-022526-j9kg00qf 4421 23 associated associate VBN cord-022526-j9kg00qf 4421 24 diarrhea diarrhea NN cord-022526-j9kg00qf 4421 25 , , , cord-022526-j9kg00qf 4421 26 probiotic probiotic JJ cord-022526-j9kg00qf 4421 27 preparations preparation NNS cord-022526-j9kg00qf 4421 28 have have VBP cord-022526-j9kg00qf 4421 29 been be VBN cord-022526-j9kg00qf 4421 30 advocated advocate VBN cord-022526-j9kg00qf 4421 31 to to TO cord-022526-j9kg00qf 4421 32 treat treat VB cord-022526-j9kg00qf 4421 33 affected affected JJ cord-022526-j9kg00qf 4421 34 horses horse NNS cord-022526-j9kg00qf 4421 35 . . . cord-022526-j9kg00qf 4422 1 Sour sour JJ cord-022526-j9kg00qf 4422 2 milk milk NN cord-022526-j9kg00qf 4422 3 , , , cord-022526-j9kg00qf 4422 4 a a DT cord-022526-j9kg00qf 4422 5 product product NN cord-022526-j9kg00qf 4422 6 containing contain VBG cord-022526-j9kg00qf 4422 7 lactose lactose NN cord-022526-j9kg00qf 4422 8 - - HYPH cord-022526-j9kg00qf 4422 9 producing produce VBG cord-022526-j9kg00qf 4422 10 Streptococcus streptococcus NN cord-022526-j9kg00qf 4422 11 species specie NNS cord-022526-j9kg00qf 4422 12 , , , cord-022526-j9kg00qf 4422 13 appears appear VBZ cord-022526-j9kg00qf 4422 14 to to TO cord-022526-j9kg00qf 4422 15 improve improve VB cord-022526-j9kg00qf 4422 16 the the DT cord-022526-j9kg00qf 4422 17 clinical clinical JJ cord-022526-j9kg00qf 4422 18 course course NN cord-022526-j9kg00qf 4422 19 greatly greatly RB cord-022526-j9kg00qf 4422 20 in in IN cord-022526-j9kg00qf 4422 21 horses horse NNS cord-022526-j9kg00qf 4422 22 suspected suspect VBN cord-022526-j9kg00qf 4422 23 of of IN cord-022526-j9kg00qf 4422 24 having have VBG cord-022526-j9kg00qf 4422 25 Clostridium clostridium NN cord-022526-j9kg00qf 4422 26 perfringens perfringens NN cord-022526-j9kg00qf 4422 27 type type NN cord-022526-j9kg00qf 4422 28 A a DT cord-022526-j9kg00qf 4422 29 infection infection NN cord-022526-j9kg00qf 4422 30 . . . cord-022526-j9kg00qf 4423 1 Sour sour JJ cord-022526-j9kg00qf 4423 2 milk milk NN cord-022526-j9kg00qf 4423 3 may may MD cord-022526-j9kg00qf 4423 4 benefit benefit VB cord-022526-j9kg00qf 4423 5 the the DT cord-022526-j9kg00qf 4423 6 patient patient NN cord-022526-j9kg00qf 4423 7 by by IN cord-022526-j9kg00qf 4423 8 altering alter VBG cord-022526-j9kg00qf 4423 9 the the DT cord-022526-j9kg00qf 4423 10 flora flora NNS cord-022526-j9kg00qf 4423 11 and and CC cord-022526-j9kg00qf 4423 12 antagonizing antagonize VBG cord-022526-j9kg00qf 4423 13 enterotoxigenic enterotoxigenic NNP cord-022526-j9kg00qf 4423 14 C. C. NNP cord-022526-j9kg00qf 4423 15 perfringens perfringens NN cord-022526-j9kg00qf 4423 16 type type NN cord-022526-j9kg00qf 4423 17 A a NN cord-022526-j9kg00qf 4423 18 but but CC cord-022526-j9kg00qf 4423 19 also also RB cord-022526-j9kg00qf 4423 20 is be VBZ cord-022526-j9kg00qf 4423 21 reported report VBN cord-022526-j9kg00qf 4423 22 to to TO cord-022526-j9kg00qf 4423 23 be be VB cord-022526-j9kg00qf 4423 24 bactericidal bactericidal JJ cord-022526-j9kg00qf 4423 25 against against IN cord-022526-j9kg00qf 4423 26 C. C. NNP cord-022526-j9kg00qf 4423 27 perfringens perfringens NN cord-022526-j9kg00qf 4423 28 type type NN cord-022526-j9kg00qf 4423 29 A. a. NN cord-022526-j9kg00qf 4423 30 78 78 CD cord-022526-j9kg00qf 4423 31 Preparations Preparations NNPS cord-022526-j9kg00qf 4423 32 of of IN cord-022526-j9kg00qf 4423 33 Saccharomyces Saccharomyces NNP cord-022526-j9kg00qf 4423 34 boulardi boulardi NNS cord-022526-j9kg00qf 4423 35 are be VBP cord-022526-j9kg00qf 4423 36 effective effective JJ cord-022526-j9kg00qf 4423 37 for for IN cord-022526-j9kg00qf 4423 38 reducing reduce VBG cord-022526-j9kg00qf 4423 39 diarrhea diarrhea NN cord-022526-j9kg00qf 4423 40 and and CC cord-022526-j9kg00qf 4423 41 the the DT cord-022526-j9kg00qf 4423 42 frequency frequency NN cord-022526-j9kg00qf 4423 43 of of IN cord-022526-j9kg00qf 4423 44 C. C. NNP cord-022526-j9kg00qf 4423 45 difficile difficile NN cord-022526-j9kg00qf 4423 46 recurrence recurrence NN cord-022526-j9kg00qf 4423 47 in in IN cord-022526-j9kg00qf 4423 48 human human JJ cord-022526-j9kg00qf 4423 49 beings being NNS cord-022526-j9kg00qf 4423 50 . . . cord-022526-j9kg00qf 4424 1 83 83 CD cord-022526-j9kg00qf 4425 1 However however RB cord-022526-j9kg00qf 4425 2 , , , cord-022526-j9kg00qf 4425 3 whether whether IN cord-022526-j9kg00qf 4425 4 relapse relapse NN cord-022526-j9kg00qf 4425 5 is be VBZ cord-022526-j9kg00qf 4425 6 a a DT cord-022526-j9kg00qf 4425 7 problem problem NN cord-022526-j9kg00qf 4425 8 in in IN cord-022526-j9kg00qf 4425 9 horses horse NNS cord-022526-j9kg00qf 4425 10 with with IN cord-022526-j9kg00qf 4425 11 C. C. NNP cord-022526-j9kg00qf 4425 12 difficile difficile NN cord-022526-j9kg00qf 4425 13 colitis colitis NN cord-022526-j9kg00qf 4425 14 is be VBZ cord-022526-j9kg00qf 4425 15 not not RB cord-022526-j9kg00qf 4425 16 clear clear JJ cord-022526-j9kg00qf 4425 17 . . . cord-022526-j9kg00qf 4426 1 Lactobacillus lactobacillus NN cord-022526-j9kg00qf 4426 2 preparations preparation NNS cord-022526-j9kg00qf 4426 3 have have VBP cord-022526-j9kg00qf 4426 4 a a DT cord-022526-j9kg00qf 4426 5 protective protective JJ cord-022526-j9kg00qf 4426 6 effect effect NN cord-022526-j9kg00qf 4426 7 in in IN cord-022526-j9kg00qf 4426 8 human human JJ cord-022526-j9kg00qf 4426 9 beings being NNS cord-022526-j9kg00qf 4426 10 and and CC cord-022526-j9kg00qf 4426 11 decrease decrease VB cord-022526-j9kg00qf 4426 12 the the DT cord-022526-j9kg00qf 4426 13 severity severity NN cord-022526-j9kg00qf 4426 14 and and CC cord-022526-j9kg00qf 4426 15 duration duration NN cord-022526-j9kg00qf 4426 16 of of IN cord-022526-j9kg00qf 4426 17 antibioticassociated antibioticassociated JJ cord-022526-j9kg00qf 4426 18 diarrhea diarrhea NN cord-022526-j9kg00qf 4426 19 . . . cord-022526-j9kg00qf 4427 1 242 242 CD cord-022526-j9kg00qf 4427 2 , , , cord-022526-j9kg00qf 4427 3 243 243 CD cord-022526-j9kg00qf 4428 1 However however RB cord-022526-j9kg00qf 4428 2 , , , cord-022526-j9kg00qf 4428 3 evidence evidence NN cord-022526-j9kg00qf 4428 4 of of IN cord-022526-j9kg00qf 4428 5 their -PRON- PRP$ cord-022526-j9kg00qf 4428 6 clinical clinical JJ cord-022526-j9kg00qf 4428 7 usefulness usefulness NN cord-022526-j9kg00qf 4428 8 in in IN cord-022526-j9kg00qf 4428 9 horses horse NNS cord-022526-j9kg00qf 4428 10 is be VBZ cord-022526-j9kg00qf 4428 11 lacking lack VBG cord-022526-j9kg00qf 4428 12 . . . cord-022526-j9kg00qf 4429 1 Good good JJ cord-022526-j9kg00qf 4429 2 nursing nursing NN cord-022526-j9kg00qf 4429 3 care care NN cord-022526-j9kg00qf 4429 4 and and CC cord-022526-j9kg00qf 4429 5 adequate adequate JJ cord-022526-j9kg00qf 4429 6 nutrition nutrition NN cord-022526-j9kg00qf 4429 7 are be VBP cord-022526-j9kg00qf 4429 8 vital vital JJ cord-022526-j9kg00qf 4429 9 to to IN cord-022526-j9kg00qf 4429 10 the the DT cord-022526-j9kg00qf 4429 11 treatment treatment NN cord-022526-j9kg00qf 4429 12 of of IN cord-022526-j9kg00qf 4429 13 horses horse NNS cord-022526-j9kg00qf 4429 14 with with IN cord-022526-j9kg00qf 4429 15 salmonellosis salmonellosis NN cord-022526-j9kg00qf 4429 16 . . . cord-022526-j9kg00qf 4430 1 Salmonellosis salmonellosis NN cord-022526-j9kg00qf 4430 2 is be VBZ cord-022526-j9kg00qf 4430 3 a a DT cord-022526-j9kg00qf 4430 4 severely severely RB cord-022526-j9kg00qf 4430 5 catabolic catabolic JJ cord-022526-j9kg00qf 4430 6 disease disease NN cord-022526-j9kg00qf 4430 7 , , , cord-022526-j9kg00qf 4430 8 increasing increase VBG cord-022526-j9kg00qf 4430 9 caloric caloric JJ cord-022526-j9kg00qf 4430 10 requirements requirement NNS cord-022526-j9kg00qf 4430 11 greatly greatly RB cord-022526-j9kg00qf 4430 12 . . . cord-022526-j9kg00qf 4431 1 Normal normal JJ cord-022526-j9kg00qf 4431 2 intake intake NN cord-022526-j9kg00qf 4431 3 of of IN cord-022526-j9kg00qf 4431 4 roughage roughage NN cord-022526-j9kg00qf 4431 5 to to TO cord-022526-j9kg00qf 4431 6 provide provide VB cord-022526-j9kg00qf 4431 7 energy energy NN cord-022526-j9kg00qf 4431 8 may may MD cord-022526-j9kg00qf 4431 9 be be VB cord-022526-j9kg00qf 4431 10 inadequate inadequate JJ cord-022526-j9kg00qf 4431 11 ; ; : cord-022526-j9kg00qf 4431 12 however however RB cord-022526-j9kg00qf 4431 13 , , , cord-022526-j9kg00qf 4431 14 one one PRP cord-022526-j9kg00qf 4431 15 should should MD cord-022526-j9kg00qf 4431 16 avoid avoid VB cord-022526-j9kg00qf 4431 17 feeding feeding NN cord-022526-j9kg00qf 4431 18 of of IN cord-022526-j9kg00qf 4431 19 grains grain NNS cord-022526-j9kg00qf 4431 20 to to TO cord-022526-j9kg00qf 4431 21 prevent prevent VB cord-022526-j9kg00qf 4431 22 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4431 23 overload overload NN cord-022526-j9kg00qf 4431 24 . . . cord-022526-j9kg00qf 4432 1 Dietary dietary JJ cord-022526-j9kg00qf 4432 2 management management NN cord-022526-j9kg00qf 4432 3 usually usually RB cord-022526-j9kg00qf 4432 4 consists consist VBZ cord-022526-j9kg00qf 4432 5 of of IN cord-022526-j9kg00qf 4432 6 restricting restrict VBG cord-022526-j9kg00qf 4432 7 or or CC cord-022526-j9kg00qf 4432 8 eliminating eliminate VBG cord-022526-j9kg00qf 4432 9 long long JJ cord-022526-j9kg00qf 4432 10 - - HYPH cord-022526-j9kg00qf 4432 11 stem stem NN cord-022526-j9kg00qf 4432 12 roughage roughage NN cord-022526-j9kg00qf 4432 13 ( ( -LRB- cord-022526-j9kg00qf 4432 14 hay hay NN cord-022526-j9kg00qf 4432 15 ) ) -RRB- cord-022526-j9kg00qf 4432 16 from from IN cord-022526-j9kg00qf 4432 17 the the DT cord-022526-j9kg00qf 4432 18 diet diet NN cord-022526-j9kg00qf 4432 19 and and CC cord-022526-j9kg00qf 4432 20 feeding feed VBG cord-022526-j9kg00qf 4432 21 exclusively exclusively RB cord-022526-j9kg00qf 4432 22 a a DT cord-022526-j9kg00qf 4432 23 complete complete JJ cord-022526-j9kg00qf 4432 24 pelleted pellete VBN cord-022526-j9kg00qf 4432 25 diet diet NN cord-022526-j9kg00qf 4432 26 ( ( -LRB- cord-022526-j9kg00qf 4432 27 at at RB cord-022526-j9kg00qf 4432 28 least least RBS cord-022526-j9kg00qf 4432 29 30 30 CD cord-022526-j9kg00qf 4432 30 % % NN cord-022526-j9kg00qf 4432 31 dietary dietary JJ cord-022526-j9kg00qf 4432 32 fiber fiber NN cord-022526-j9kg00qf 4432 33 ) ) -RRB- cord-022526-j9kg00qf 4432 34 . . . cord-022526-j9kg00qf 4433 1 The the DT cord-022526-j9kg00qf 4433 2 rationale rationale NN cord-022526-j9kg00qf 4433 3 behind behind IN cord-022526-j9kg00qf 4433 4 this this DT cord-022526-j9kg00qf 4433 5 recommendation recommendation NN cord-022526-j9kg00qf 4433 6 is be VBZ cord-022526-j9kg00qf 4433 7 to to TO cord-022526-j9kg00qf 4433 8 reduce reduce VB cord-022526-j9kg00qf 4433 9 the the DT cord-022526-j9kg00qf 4433 10 mechanical mechanical JJ cord-022526-j9kg00qf 4433 11 load load NN cord-022526-j9kg00qf 4433 12 on on IN cord-022526-j9kg00qf 4433 13 the the DT cord-022526-j9kg00qf 4433 14 colon colon NN cord-022526-j9kg00qf 4433 15 . . . cord-022526-j9kg00qf 4434 1 Frequent frequent JJ cord-022526-j9kg00qf 4434 2 meals meal NNS cord-022526-j9kg00qf 4434 3 ( ( -LRB- cord-022526-j9kg00qf 4434 4 4 4 CD cord-022526-j9kg00qf 4434 5 to to TO cord-022526-j9kg00qf 4434 6 6 6 CD cord-022526-j9kg00qf 4434 7 times time NNS cord-022526-j9kg00qf 4434 8 a a DT cord-022526-j9kg00qf 4434 9 day day NN cord-022526-j9kg00qf 4434 10 ) ) -RRB- cord-022526-j9kg00qf 4434 11 are be VBP cord-022526-j9kg00qf 4434 12 recommended recommend VBN cord-022526-j9kg00qf 4434 13 . . . cord-022526-j9kg00qf 4435 1 One one PRP cord-022526-j9kg00qf 4435 2 can can MD cord-022526-j9kg00qf 4435 3 add add VB cord-022526-j9kg00qf 4435 4 corn corn NN cord-022526-j9kg00qf 4435 5 oil oil NN cord-022526-j9kg00qf 4435 6 ( ( -LRB- cord-022526-j9kg00qf 4435 7 1 1 CD cord-022526-j9kg00qf 4435 8 cup cup NN cord-022526-j9kg00qf 4435 9 every every DT cord-022526-j9kg00qf 4435 10 12 12 CD cord-022526-j9kg00qf 4435 11 to to TO cord-022526-j9kg00qf 4435 12 24 24 CD cord-022526-j9kg00qf 4435 13 hours hour NNS cord-022526-j9kg00qf 4435 14 ) ) -RRB- cord-022526-j9kg00qf 4435 15 to to IN cord-022526-j9kg00qf 4435 16 the the DT cord-022526-j9kg00qf 4435 17 pellets pellet NNS cord-022526-j9kg00qf 4435 18 to to TO cord-022526-j9kg00qf 4435 19 increase increase VB cord-022526-j9kg00qf 4435 20 the the DT cord-022526-j9kg00qf 4435 21 caloric caloric JJ cord-022526-j9kg00qf 4435 22 intake intake NN cord-022526-j9kg00qf 4435 23 without without IN cord-022526-j9kg00qf 4435 24 adding add VBG cord-022526-j9kg00qf 4435 25 roughage roughage NN cord-022526-j9kg00qf 4435 26 or or CC cord-022526-j9kg00qf 4435 27 grain grain NN cord-022526-j9kg00qf 4435 28 . . . cord-022526-j9kg00qf 4436 1 One one PRP cord-022526-j9kg00qf 4436 2 should should MD cord-022526-j9kg00qf 4436 3 note note VB cord-022526-j9kg00qf 4436 4 that that IN cord-022526-j9kg00qf 4436 5 if if IN cord-022526-j9kg00qf 4436 6 a a DT cord-022526-j9kg00qf 4436 7 horse horse NN cord-022526-j9kg00qf 4436 8 with with IN cord-022526-j9kg00qf 4436 9 colitis colitis NN cord-022526-j9kg00qf 4436 10 refuses refuse VBZ cord-022526-j9kg00qf 4436 11 to to TO cord-022526-j9kg00qf 4436 12 eat eat VB cord-022526-j9kg00qf 4436 13 pelleted pellete VBN cord-022526-j9kg00qf 4436 14 feed feed NN cord-022526-j9kg00qf 4436 15 , , , cord-022526-j9kg00qf 4436 16 then then RB cord-022526-j9kg00qf 4436 17 one one PRP cord-022526-j9kg00qf 4436 18 should should MD cord-022526-j9kg00qf 4436 19 feed feed VB cord-022526-j9kg00qf 4436 20 good good JJ cord-022526-j9kg00qf 4436 21 - - HYPH cord-022526-j9kg00qf 4436 22 quality quality NN cord-022526-j9kg00qf 4436 23 grass grass NN cord-022526-j9kg00qf 4436 24 hay hay NN cord-022526-j9kg00qf 4436 25 . . . cord-022526-j9kg00qf 4437 1 In in IN cord-022526-j9kg00qf 4437 2 anorectic anorectic JJ cord-022526-j9kg00qf 4437 3 or or CC cord-022526-j9kg00qf 4437 4 severely severely RB cord-022526-j9kg00qf 4437 5 catabolic catabolic JJ cord-022526-j9kg00qf 4437 6 patients patient NNS cord-022526-j9kg00qf 4437 7 , , , cord-022526-j9kg00qf 4437 8 enteral enteral JJ cord-022526-j9kg00qf 4437 9 and and CC cord-022526-j9kg00qf 4437 10 parenteral parenteral JJ cord-022526-j9kg00qf 4437 11 nutrition nutrition NN cord-022526-j9kg00qf 4437 12 ( ( -LRB- cord-022526-j9kg00qf 4437 13 total total JJ cord-022526-j9kg00qf 4437 14 and and CC cord-022526-j9kg00qf 4437 15 partial partial JJ cord-022526-j9kg00qf 4437 16 ) ) -RRB- cord-022526-j9kg00qf 4437 17 has have VBZ cord-022526-j9kg00qf 4437 18 been be VBN cord-022526-j9kg00qf 4437 19 used use VBN cord-022526-j9kg00qf 4437 20 successfully successfully RB cord-022526-j9kg00qf 4437 21 to to TO cord-022526-j9kg00qf 4437 22 provide provide VB cord-022526-j9kg00qf 4437 23 calories calorie NNS cord-022526-j9kg00qf 4437 24 and and CC cord-022526-j9kg00qf 4437 25 nutritional nutritional JJ cord-022526-j9kg00qf 4437 26 support support NN cord-022526-j9kg00qf 4437 27 . . . cord-022526-j9kg00qf 4438 1 Strongylus strongylus JJ cord-022526-j9kg00qf 4438 2 vulgaris vulgaris NN cord-022526-j9kg00qf 4438 3 infection infection NN cord-022526-j9kg00qf 4438 4 requires require VBZ cord-022526-j9kg00qf 4438 5 treatment treatment NN cord-022526-j9kg00qf 4438 6 of of IN cord-022526-j9kg00qf 4438 7 the the DT cord-022526-j9kg00qf 4438 8 migrating migrate VBG cord-022526-j9kg00qf 4438 9 parasite parasite NN cord-022526-j9kg00qf 4438 10 larvae larva NNS cord-022526-j9kg00qf 4438 11 and and CC cord-022526-j9kg00qf 4438 12 the the DT cord-022526-j9kg00qf 4438 13 lesions lesion NNS cord-022526-j9kg00qf 4438 14 produced produce VBN cord-022526-j9kg00qf 4438 15 by by IN cord-022526-j9kg00qf 4438 16 the the DT cord-022526-j9kg00qf 4438 17 parasite parasite NN cord-022526-j9kg00qf 4438 18 . . . cord-022526-j9kg00qf 4439 1 Fenbendazole Fenbendazole NNP cord-022526-j9kg00qf 4439 2 ( ( -LRB- cord-022526-j9kg00qf 4439 3 10 10 CD cord-022526-j9kg00qf 4439 4 mg mg NN cord-022526-j9kg00qf 4439 5 / / SYM cord-022526-j9kg00qf 4439 6 kg kg XX cord-022526-j9kg00qf 4439 7 orally orally RB cord-022526-j9kg00qf 4439 8 every every DT cord-022526-j9kg00qf 4439 9 24 24 CD cord-022526-j9kg00qf 4439 10 hours hour NNS cord-022526-j9kg00qf 4439 11 for for IN cord-022526-j9kg00qf 4439 12 3 3 CD cord-022526-j9kg00qf 4439 13 days day NNS cord-022526-j9kg00qf 4439 14 or or CC cord-022526-j9kg00qf 4439 15 10 10 CD cord-022526-j9kg00qf 4439 16 mg mg NNS cord-022526-j9kg00qf 4439 17 / / SYM cord-022526-j9kg00qf 4439 18 kg kg XX cord-022526-j9kg00qf 4439 19 orally orally RB cord-022526-j9kg00qf 4440 1 every every DT cord-022526-j9kg00qf 4440 2 24 24 CD cord-022526-j9kg00qf 4440 3 hours hour NNS cord-022526-j9kg00qf 4440 4 for for IN cord-022526-j9kg00qf 4440 5 5 5 CD cord-022526-j9kg00qf 4440 6 days day NNS cord-022526-j9kg00qf 4440 7 ) ) -RRB- cord-022526-j9kg00qf 4440 8 and and CC cord-022526-j9kg00qf 4440 9 ivermectin ivermectin NNP cord-022526-j9kg00qf 4440 10 ( ( -LRB- cord-022526-j9kg00qf 4440 11 200 200 CD cord-022526-j9kg00qf 4440 12 mg mg NNP cord-022526-j9kg00qf 4440 13 / / SYM cord-022526-j9kg00qf 4440 14 kg kg NNP cord-022526-j9kg00qf 4440 15 orally orally RB cord-022526-j9kg00qf 4440 16 ) ) -RRB- cord-022526-j9kg00qf 4440 17 are be VBP cord-022526-j9kg00qf 4440 18 effective effective JJ cord-022526-j9kg00qf 4440 19 in in IN cord-022526-j9kg00qf 4440 20 killing kill VBG cord-022526-j9kg00qf 4440 21 fourth fourth JJ cord-022526-j9kg00qf 4440 22 - - HYPH cord-022526-j9kg00qf 4440 23 stage stage NN cord-022526-j9kg00qf 4440 24 larvae larva NNS cord-022526-j9kg00qf 4440 25 . . . cord-022526-j9kg00qf 4441 1 121 121 CD cord-022526-j9kg00qf 4441 2 Other other JJ cord-022526-j9kg00qf 4441 3 anthelmintics anthelmintic NNS cord-022526-j9kg00qf 4441 4 also also RB cord-022526-j9kg00qf 4441 5 may may MD cord-022526-j9kg00qf 4441 6 be be VB cord-022526-j9kg00qf 4441 7 906 906 CD cord-022526-j9kg00qf 4441 8 PART part NN cord-022526-j9kg00qf 4441 9 II ii CD cord-022526-j9kg00qf 4441 10 Disorders disorder NNS cord-022526-j9kg00qf 4441 11 of of IN cord-022526-j9kg00qf 4441 12 Specific specific JJ cord-022526-j9kg00qf 4441 13 Body Body NNP cord-022526-j9kg00qf 4441 14 Systems Systems NNPS cord-022526-j9kg00qf 4441 15 effective effective JJ cord-022526-j9kg00qf 4441 16 when when WRB cord-022526-j9kg00qf 4441 17 given give VBN cord-022526-j9kg00qf 4441 18 at at IN cord-022526-j9kg00qf 4441 19 higher high JJR cord-022526-j9kg00qf 4441 20 doses dose NNS cord-022526-j9kg00qf 4441 21 than than IN cord-022526-j9kg00qf 4441 22 those those DT cord-022526-j9kg00qf 4441 23 required require VBN cord-022526-j9kg00qf 4441 24 to to TO cord-022526-j9kg00qf 4441 25 kill kill VB cord-022526-j9kg00qf 4441 26 adult adult NN cord-022526-j9kg00qf 4441 27 worms worm NNS cord-022526-j9kg00qf 4441 28 . . . cord-022526-j9kg00qf 4442 1 The the DT cord-022526-j9kg00qf 4442 2 efficacy efficacy NN cord-022526-j9kg00qf 4442 3 of of IN cord-022526-j9kg00qf 4442 4 these these DT cord-022526-j9kg00qf 4442 5 anthelmintics anthelmintic NNS cord-022526-j9kg00qf 4442 6 against against IN cord-022526-j9kg00qf 4442 7 larvae larva NNS cord-022526-j9kg00qf 4442 8 within within IN cord-022526-j9kg00qf 4442 9 thrombi thrombi NNP cord-022526-j9kg00qf 4442 10 is be VBZ cord-022526-j9kg00qf 4442 11 not not RB cord-022526-j9kg00qf 4442 12 known know VBN cord-022526-j9kg00qf 4442 13 . . . cord-022526-j9kg00qf 4443 1 Thrombolytic thrombolytic JJ cord-022526-j9kg00qf 4443 2 and and CC cord-022526-j9kg00qf 4443 3 antithrombotic antithrombotic JJ cord-022526-j9kg00qf 4443 4 therapy therapy NN cord-022526-j9kg00qf 4443 5 has have VBZ cord-022526-j9kg00qf 4443 6 been be VBN cord-022526-j9kg00qf 4443 7 advocated advocate VBN cord-022526-j9kg00qf 4443 8 in in IN cord-022526-j9kg00qf 4443 9 horses horse NNS cord-022526-j9kg00qf 4443 10 with with IN cord-022526-j9kg00qf 4443 11 suspected suspect VBN cord-022526-j9kg00qf 4443 12 strongylosis strongylosis NN cord-022526-j9kg00qf 4443 13 . . . cord-022526-j9kg00qf 4444 1 121 121 CD cord-022526-j9kg00qf 4444 2 , , , cord-022526-j9kg00qf 4444 3 128 128 CD cord-022526-j9kg00qf 4444 4 Heparin Heparin NNP cord-022526-j9kg00qf 4444 5 ( ( -LRB- cord-022526-j9kg00qf 4444 6 20 20 CD cord-022526-j9kg00qf 4444 7 to to TO cord-022526-j9kg00qf 4444 8 80 80 CD cord-022526-j9kg00qf 4444 9 IU IU NNP cord-022526-j9kg00qf 4444 10 intravenously intravenously RB cord-022526-j9kg00qf 4444 11 or or CC cord-022526-j9kg00qf 4444 12 subcutaneously subcutaneously RB cord-022526-j9kg00qf 4444 13 every every DT cord-022526-j9kg00qf 4444 14 6 6 CD cord-022526-j9kg00qf 4444 15 to to TO cord-022526-j9kg00qf 4444 16 12 12 CD cord-022526-j9kg00qf 4444 17 hours hour NNS cord-022526-j9kg00qf 4444 18 ) ) -RRB- cord-022526-j9kg00qf 4444 19 is be VBZ cord-022526-j9kg00qf 4444 20 often often RB cord-022526-j9kg00qf 4444 21 administered administer VBN cord-022526-j9kg00qf 4444 22 as as IN cord-022526-j9kg00qf 4444 23 an an DT cord-022526-j9kg00qf 4444 24 anticoagulant anticoagulant NN cord-022526-j9kg00qf 4444 25 . . . cord-022526-j9kg00qf 4445 1 Aspirin aspirin NN cord-022526-j9kg00qf 4445 2 ( ( -LRB- cord-022526-j9kg00qf 4445 3 10 10 CD cord-022526-j9kg00qf 4445 4 to to TO cord-022526-j9kg00qf 4445 5 30 30 CD cord-022526-j9kg00qf 4445 6 mg mg NN cord-022526-j9kg00qf 4445 7 / / SYM cord-022526-j9kg00qf 4445 8 kg kg XX cord-022526-j9kg00qf 4445 9 orally orally RB cord-022526-j9kg00qf 4445 10 every every DT cord-022526-j9kg00qf 4445 11 12 12 CD cord-022526-j9kg00qf 4445 12 to to TO cord-022526-j9kg00qf 4445 13 48 48 CD cord-022526-j9kg00qf 4445 14 hours hour NNS cord-022526-j9kg00qf 4445 15 ) ) -RRB- cord-022526-j9kg00qf 4445 16 is be VBZ cord-022526-j9kg00qf 4445 17 usually usually RB cord-022526-j9kg00qf 4445 18 combined combine VBN cord-022526-j9kg00qf 4445 19 with with IN cord-022526-j9kg00qf 4445 20 heparin heparin NN cord-022526-j9kg00qf 4445 21 to to TO cord-022526-j9kg00qf 4445 22 inhibit inhibit VB cord-022526-j9kg00qf 4445 23 platelet platelet NN cord-022526-j9kg00qf 4445 24 adhesion adhesion NN cord-022526-j9kg00qf 4445 25 . . . cord-022526-j9kg00qf 4446 1 Aspirin aspirin NN cord-022526-j9kg00qf 4446 2 also also RB cord-022526-j9kg00qf 4446 3 may may MD cord-022526-j9kg00qf 4446 4 inhibit inhibit VB cord-022526-j9kg00qf 4446 5 release release NN cord-022526-j9kg00qf 4446 6 of of IN cord-022526-j9kg00qf 4446 7 platelet platelet NN cord-022526-j9kg00qf 4446 8 products product NNS cord-022526-j9kg00qf 4446 9 such such JJ cord-022526-j9kg00qf 4446 10 as as IN cord-022526-j9kg00qf 4446 11 thromboxane thromboxane NN cord-022526-j9kg00qf 4446 12 that that WDT cord-022526-j9kg00qf 4446 13 affect affect VBP cord-022526-j9kg00qf 4446 14 the the DT cord-022526-j9kg00qf 4446 15 motility motility NN cord-022526-j9kg00qf 4446 16 of of IN cord-022526-j9kg00qf 4446 17 the the DT cord-022526-j9kg00qf 4446 18 large large JJ cord-022526-j9kg00qf 4446 19 intestine intestine NN cord-022526-j9kg00qf 4446 20 . . . cord-022526-j9kg00qf 4447 1 Low low JJ cord-022526-j9kg00qf 4447 2 - - HYPH cord-022526-j9kg00qf 4447 3 molecular molecular JJ cord-022526-j9kg00qf 4447 4 - - HYPH cord-022526-j9kg00qf 4447 5 weight weight NN cord-022526-j9kg00qf 4447 6 dextrans dextran NNS cord-022526-j9kg00qf 4447 7 have have VBP cord-022526-j9kg00qf 4447 8 been be VBN cord-022526-j9kg00qf 4447 9 advocated advocate VBN cord-022526-j9kg00qf 4447 10 as as IN cord-022526-j9kg00qf 4447 11 antithrombotics antithrombotic NNS cord-022526-j9kg00qf 4447 12 that that WDT cord-022526-j9kg00qf 4447 13 act act VBP cord-022526-j9kg00qf 4447 14 by by IN cord-022526-j9kg00qf 4447 15 inhibiting inhibit VBG cord-022526-j9kg00qf 4447 16 platelet platelet NN cord-022526-j9kg00qf 4447 17 function function NN cord-022526-j9kg00qf 4447 18 and and CC cord-022526-j9kg00qf 4447 19 coagulation coagulation NN cord-022526-j9kg00qf 4447 20 . . . cord-022526-j9kg00qf 4448 1 128 128 CD cord-022526-j9kg00qf 4448 2 , , , cord-022526-j9kg00qf 4448 3 218 218 CD cord-022526-j9kg00qf 4449 1 The the DT cord-022526-j9kg00qf 4449 2 clinical clinical JJ cord-022526-j9kg00qf 4449 3 efficacy efficacy NN cord-022526-j9kg00qf 4449 4 of of IN cord-022526-j9kg00qf 4449 5 dextran dextran NN cord-022526-j9kg00qf 4449 6 administration administration NN cord-022526-j9kg00qf 4449 7 appears appear VBZ cord-022526-j9kg00qf 4449 8 to to TO cord-022526-j9kg00qf 4449 9 be be VB cord-022526-j9kg00qf 4449 10 good good JJ cord-022526-j9kg00qf 4449 11 , , , cord-022526-j9kg00qf 4449 12 but but CC cord-022526-j9kg00qf 4449 13 no no DT cord-022526-j9kg00qf 4449 14 controlled control VBN cord-022526-j9kg00qf 4449 15 studies study NNS cord-022526-j9kg00qf 4449 16 have have VBP cord-022526-j9kg00qf 4449 17 been be VBN cord-022526-j9kg00qf 4449 18 performed perform VBN cord-022526-j9kg00qf 4449 19 . . . cord-022526-j9kg00qf 4450 1 Anthelmintic Anthelmintic NNP cord-022526-j9kg00qf 4450 2 administration administration NN cord-022526-j9kg00qf 4450 3 is be VBZ cord-022526-j9kg00qf 4450 4 usually usually RB cord-022526-j9kg00qf 4450 5 the the DT cord-022526-j9kg00qf 4450 6 only only JJ cord-022526-j9kg00qf 4450 7 treatment treatment NN cord-022526-j9kg00qf 4450 8 necessary necessary JJ cord-022526-j9kg00qf 4450 9 for for IN cord-022526-j9kg00qf 4450 10 mild mild JJ cord-022526-j9kg00qf 4450 11 to to IN cord-022526-j9kg00qf 4450 12 moderate moderate JJ cord-022526-j9kg00qf 4450 13 cases case NNS cord-022526-j9kg00qf 4450 14 of of IN cord-022526-j9kg00qf 4450 15 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 4450 16 treated treat VBN cord-022526-j9kg00qf 4450 17 early early RB cord-022526-j9kg00qf 4450 18 in in IN cord-022526-j9kg00qf 4450 19 the the DT cord-022526-j9kg00qf 4450 20 course course NN cord-022526-j9kg00qf 4450 21 of of IN cord-022526-j9kg00qf 4450 22 the the DT cord-022526-j9kg00qf 4450 23 disease disease NN cord-022526-j9kg00qf 4450 24 ( ( -LRB- cord-022526-j9kg00qf 4450 25 within within IN cord-022526-j9kg00qf 4450 26 1 1 CD cord-022526-j9kg00qf 4450 27 to to IN cord-022526-j9kg00qf 4450 28 3 3 CD cord-022526-j9kg00qf 4450 29 weeks week NNS cord-022526-j9kg00qf 4450 30 of of IN cord-022526-j9kg00qf 4450 31 onset onset NN cord-022526-j9kg00qf 4450 32 ) ) -RRB- cord-022526-j9kg00qf 4450 33 . . . cord-022526-j9kg00qf 4451 1 Fenbendazole Fenbendazole NNP cord-022526-j9kg00qf 4451 2 is be VBZ cord-022526-j9kg00qf 4451 3 effective effective JJ cord-022526-j9kg00qf 4451 4 against against IN cord-022526-j9kg00qf 4451 5 many many JJ cord-022526-j9kg00qf 4451 6 larval larval JJ cord-022526-j9kg00qf 4451 7 stages stage NNS cord-022526-j9kg00qf 4451 8 , , , cord-022526-j9kg00qf 4451 9 but but CC cord-022526-j9kg00qf 4451 10 resistance resistance NN cord-022526-j9kg00qf 4451 11 is be VBZ cord-022526-j9kg00qf 4451 12 increasing increase VBG cord-022526-j9kg00qf 4451 13 . . . cord-022526-j9kg00qf 4452 1 Although although IN cord-022526-j9kg00qf 4452 2 the the DT cord-022526-j9kg00qf 4452 3 reported report VBN cord-022526-j9kg00qf 4452 4 efficacy efficacy NN cord-022526-j9kg00qf 4452 5 of of IN cord-022526-j9kg00qf 4452 6 ivermectin ivermectin NNP cord-022526-j9kg00qf 4452 7 varies vary VBZ cord-022526-j9kg00qf 4452 8 against against IN cord-022526-j9kg00qf 4452 9 certain certain JJ cord-022526-j9kg00qf 4452 10 stages stage NNS cord-022526-j9kg00qf 4452 11 , , , cord-022526-j9kg00qf 4452 12 244 244 CD cord-022526-j9kg00qf 4452 13 one one CD cord-022526-j9kg00qf 4452 14 study study NN cord-022526-j9kg00qf 4452 15 reported report VBD cord-022526-j9kg00qf 4452 16 an an DT cord-022526-j9kg00qf 4452 17 overall overall JJ cord-022526-j9kg00qf 4452 18 efficacy efficacy NN cord-022526-j9kg00qf 4452 19 of of IN cord-022526-j9kg00qf 4452 20 75 75 CD cord-022526-j9kg00qf 4452 21 % % NN cord-022526-j9kg00qf 4452 22 . . . cord-022526-j9kg00qf 4453 1 245 245 CD cord-022526-j9kg00qf 4454 1 Currently currently RB cord-022526-j9kg00qf 4454 2 , , , cord-022526-j9kg00qf 4454 3 fenbendazole fenbendazole NNP cord-022526-j9kg00qf 4454 4 ( ( -LRB- cord-022526-j9kg00qf 4454 5 7.5 7.5 CD cord-022526-j9kg00qf 4454 6 to to TO cord-022526-j9kg00qf 4454 7 10 10 CD cord-022526-j9kg00qf 4454 8 mg mg NN cord-022526-j9kg00qf 4454 9 / / SYM cord-022526-j9kg00qf 4454 10 kg kg XX cord-022526-j9kg00qf 4454 11 orally orally RB cord-022526-j9kg00qf 4454 12 every every DT cord-022526-j9kg00qf 4454 13 24 24 CD cord-022526-j9kg00qf 4454 14 hours hour NNS cord-022526-j9kg00qf 4454 15 for for IN cord-022526-j9kg00qf 4454 16 5 5 CD cord-022526-j9kg00qf 4454 17 days day NNS cord-022526-j9kg00qf 4454 18 ) ) -RRB- cord-022526-j9kg00qf 4454 19 followed follow VBD cord-022526-j9kg00qf 4454 20 on on IN cord-022526-j9kg00qf 4454 21 day day NN cord-022526-j9kg00qf 4454 22 6 6 CD cord-022526-j9kg00qf 4454 23 by by IN cord-022526-j9kg00qf 4454 24 ivermectin ivermectin NNP cord-022526-j9kg00qf 4454 25 ( ( -LRB- cord-022526-j9kg00qf 4454 26 200 200 CD cord-022526-j9kg00qf 4454 27 mg mg NNP cord-022526-j9kg00qf 4454 28 / / SYM cord-022526-j9kg00qf 4454 29 kg kg NNP cord-022526-j9kg00qf 4454 30 orally orally RB cord-022526-j9kg00qf 4454 31 ) ) -RRB- cord-022526-j9kg00qf 4454 32 is be VBZ cord-022526-j9kg00qf 4454 33 the the DT cord-022526-j9kg00qf 4454 34 most most RBS cord-022526-j9kg00qf 4454 35 commonly commonly RB cord-022526-j9kg00qf 4454 36 advocated advocate VBN cord-022526-j9kg00qf 4454 37 treatment treatment NN cord-022526-j9kg00qf 4454 38 regimen regimen NN cord-022526-j9kg00qf 4454 39 . . . cord-022526-j9kg00qf 4455 1 133 133 CD cord-022526-j9kg00qf 4455 2 , , , cord-022526-j9kg00qf 4455 3 246 246 CD cord-022526-j9kg00qf 4455 4 Moxidectin Moxidectin NNP cord-022526-j9kg00qf 4455 5 ( ( -LRB- cord-022526-j9kg00qf 4455 6 400 400 CD cord-022526-j9kg00qf 4455 7 µg µg NN cord-022526-j9kg00qf 4455 8 / / SYM cord-022526-j9kg00qf 4455 9 kg kg CC cord-022526-j9kg00qf 4455 10 orally orally RB cord-022526-j9kg00qf 4455 11 once once IN cord-022526-j9kg00qf 4455 12 daily daily RB cord-022526-j9kg00qf 4455 13 ) ) -RRB- cord-022526-j9kg00qf 4455 14 also also RB cord-022526-j9kg00qf 4455 15 may may MD cord-022526-j9kg00qf 4455 16 be be VB cord-022526-j9kg00qf 4455 17 effective effective JJ cord-022526-j9kg00qf 4455 18 against against IN cord-022526-j9kg00qf 4455 19 adults adult NNS cord-022526-j9kg00qf 4455 20 and and CC cord-022526-j9kg00qf 4455 21 L L NNP cord-022526-j9kg00qf 4455 22 3 3 CD cord-022526-j9kg00qf 4455 23 and and CC cord-022526-j9kg00qf 4455 24 L L NNP cord-022526-j9kg00qf 4455 25 4 4 CD cord-022526-j9kg00qf 4455 26 larval larval JJ cord-022526-j9kg00qf 4455 27 stages stage NNS cord-022526-j9kg00qf 4455 28 247 247 CD cord-022526-j9kg00qf 4455 29 and and CC cord-022526-j9kg00qf 4455 30 may may MD cord-022526-j9kg00qf 4455 31 be be VB cord-022526-j9kg00qf 4455 32 useful useful JJ cord-022526-j9kg00qf 4455 33 for for IN cord-022526-j9kg00qf 4455 34 treating treat VBG cord-022526-j9kg00qf 4455 35 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 4455 36 . . . cord-022526-j9kg00qf 4456 1 Antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 4456 2 therapy therapy NN cord-022526-j9kg00qf 4456 3 also also RB cord-022526-j9kg00qf 4456 4 may may MD cord-022526-j9kg00qf 4456 5 be be VB cord-022526-j9kg00qf 4456 6 beneficial beneficial JJ cord-022526-j9kg00qf 4456 7 , , , cord-022526-j9kg00qf 4456 8 especially especially RB cord-022526-j9kg00qf 4456 9 in in IN cord-022526-j9kg00qf 4456 10 severe severe JJ cord-022526-j9kg00qf 4456 11 or or CC cord-022526-j9kg00qf 4456 12 refractory refractory JJ cord-022526-j9kg00qf 4456 13 cases case NNS cord-022526-j9kg00qf 4456 14 . . . cord-022526-j9kg00qf 4457 1 NSAID NSAID NNP cord-022526-j9kg00qf 4457 2 administration administration NN cord-022526-j9kg00qf 4457 3 may may MD cord-022526-j9kg00qf 4457 4 have have VB cord-022526-j9kg00qf 4457 5 limited limit VBN cord-022526-j9kg00qf 4457 6 value value NN cord-022526-j9kg00qf 4457 7 , , , cord-022526-j9kg00qf 4457 8 but but CC cord-022526-j9kg00qf 4457 9 dexamethasone dexamethasone NN cord-022526-j9kg00qf 4457 10 appears appear VBZ cord-022526-j9kg00qf 4457 11 to to TO cord-022526-j9kg00qf 4457 12 be be VB cord-022526-j9kg00qf 4457 13 efficacious efficacious JJ cord-022526-j9kg00qf 4457 14 in in IN cord-022526-j9kg00qf 4457 15 refractory refractory JJ cord-022526-j9kg00qf 4457 16 cases case NNS cord-022526-j9kg00qf 4457 17 when when WRB cord-022526-j9kg00qf 4457 18 used use VBN cord-022526-j9kg00qf 4457 19 with with IN cord-022526-j9kg00qf 4457 20 larvicidal larvicidal NNP cord-022526-j9kg00qf 4457 21 anthelmintics anthelmintics NNP cord-022526-j9kg00qf 4457 22 . . . cord-022526-j9kg00qf 4458 1 133 133 CD cord-022526-j9kg00qf 4458 2 , , , cord-022526-j9kg00qf 4458 3 136 136 CD cord-022526-j9kg00qf 4458 4 Pretreatment Pretreatment NNP cord-022526-j9kg00qf 4458 5 with with IN cord-022526-j9kg00qf 4458 6 dexamethasone dexamethasone NN cord-022526-j9kg00qf 4458 7 or or CC cord-022526-j9kg00qf 4458 8 prednisolone prednisolone NN cord-022526-j9kg00qf 4458 9 is be VBZ cord-022526-j9kg00qf 4458 10 indicated indicate VBN cord-022526-j9kg00qf 4458 11 before before IN cord-022526-j9kg00qf 4458 12 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 4458 13 administration administration NN cord-022526-j9kg00qf 4458 14 if if IN cord-022526-j9kg00qf 4458 15 heavy heavy JJ cord-022526-j9kg00qf 4458 16 larval larval JJ cord-022526-j9kg00qf 4458 17 loads load NNS cord-022526-j9kg00qf 4458 18 are be VBP cord-022526-j9kg00qf 4458 19 suspected suspect VBN cord-022526-j9kg00qf 4458 20 to to TO cord-022526-j9kg00qf 4458 21 prevent prevent VB cord-022526-j9kg00qf 4458 22 an an DT cord-022526-j9kg00qf 4458 23 acute acute JJ cord-022526-j9kg00qf 4458 24 exacerbation exacerbation NN cord-022526-j9kg00qf 4458 25 of of IN cord-022526-j9kg00qf 4458 26 the the DT cord-022526-j9kg00qf 4458 27 disease disease NN cord-022526-j9kg00qf 4458 28 by by IN cord-022526-j9kg00qf 4458 29 rapid rapid JJ cord-022526-j9kg00qf 4458 30 death death NN cord-022526-j9kg00qf 4458 31 of of IN cord-022526-j9kg00qf 4458 32 encysted encysted JJ cord-022526-j9kg00qf 4458 33 larvae larva NNS cord-022526-j9kg00qf 4458 34 . . . cord-022526-j9kg00qf 4459 1 Bismuth Bismuth NNP cord-022526-j9kg00qf 4459 2 subsalicylate subsalicylate NN cord-022526-j9kg00qf 4459 3 often often RB cord-022526-j9kg00qf 4459 4 is be VBZ cord-022526-j9kg00qf 4459 5 administered administer VBN cord-022526-j9kg00qf 4459 6 orally orally RB cord-022526-j9kg00qf 4459 7 as as IN cord-022526-j9kg00qf 4459 8 an an DT cord-022526-j9kg00qf 4459 9 antisecretory antisecretory NN cord-022526-j9kg00qf 4459 10 agent agent NN cord-022526-j9kg00qf 4459 11 in in IN cord-022526-j9kg00qf 4459 12 young young JJ cord-022526-j9kg00qf 4459 13 animals animal NNS cord-022526-j9kg00qf 4459 14 . . . cord-022526-j9kg00qf 4460 1 Supportive supportive JJ cord-022526-j9kg00qf 4460 2 care care NN cord-022526-j9kg00qf 4460 3 may may MD cord-022526-j9kg00qf 4460 4 be be VB cord-022526-j9kg00qf 4460 5 necessary necessary JJ cord-022526-j9kg00qf 4460 6 in in IN cord-022526-j9kg00qf 4460 7 severe severe JJ cord-022526-j9kg00qf 4460 8 cases case NNS cord-022526-j9kg00qf 4460 9 , , , cord-022526-j9kg00qf 4460 10 particularly particularly RB cord-022526-j9kg00qf 4460 11 if if IN cord-022526-j9kg00qf 4460 12 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 4460 13 is be VBZ cord-022526-j9kg00qf 4460 14 severe severe JJ cord-022526-j9kg00qf 4460 15 . . . cord-022526-j9kg00qf 4461 1 Horses horse NNS cord-022526-j9kg00qf 4461 2 occasionally occasionally RB cord-022526-j9kg00qf 4461 3 require require VBP cord-022526-j9kg00qf 4461 4 administration administration NN cord-022526-j9kg00qf 4461 5 of of IN cord-022526-j9kg00qf 4461 6 intravenous intravenous JJ cord-022526-j9kg00qf 4461 7 crystalloid crystalloid NN cord-022526-j9kg00qf 4461 8 fluids fluid NNS cord-022526-j9kg00qf 4461 9 and and CC cord-022526-j9kg00qf 4461 10 plasma plasma NN cord-022526-j9kg00qf 4461 11 or or CC cord-022526-j9kg00qf 4461 12 other other JJ cord-022526-j9kg00qf 4461 13 colloids colloid NNS cord-022526-j9kg00qf 4461 14 . . . cord-022526-j9kg00qf 4462 1 Proper proper JJ cord-022526-j9kg00qf 4462 2 nutritional nutritional JJ cord-022526-j9kg00qf 4462 3 support support NN cord-022526-j9kg00qf 4462 4 is be VBZ cord-022526-j9kg00qf 4462 5 also also RB cord-022526-j9kg00qf 4462 6 important important JJ cord-022526-j9kg00qf 4462 7 . . . cord-022526-j9kg00qf 4463 1 Supportive supportive JJ cord-022526-j9kg00qf 4463 2 care care NN cord-022526-j9kg00qf 4463 3 is be VBZ cord-022526-j9kg00qf 4463 4 the the DT cord-022526-j9kg00qf 4463 5 most most RBS cord-022526-j9kg00qf 4463 6 important important JJ cord-022526-j9kg00qf 4463 7 principle principle NN cord-022526-j9kg00qf 4463 8 of of IN cord-022526-j9kg00qf 4463 9 therapy therapy NN cord-022526-j9kg00qf 4463 10 for for IN cord-022526-j9kg00qf 4463 11 cantharidin cantharidin NNP cord-022526-j9kg00qf 4463 12 toxicity toxicity NN cord-022526-j9kg00qf 4463 13 . . . cord-022526-j9kg00qf 4464 1 Intravenous intravenous JJ cord-022526-j9kg00qf 4464 2 fluid fluid JJ cord-022526-j9kg00qf 4464 3 administration administration NN cord-022526-j9kg00qf 4464 4 ; ; : cord-022526-j9kg00qf 4464 5 maintenance maintenance NN cord-022526-j9kg00qf 4464 6 of of IN cord-022526-j9kg00qf 4464 7 electrolyte electrolyte JJ cord-022526-j9kg00qf 4464 8 balance balance NN cord-022526-j9kg00qf 4464 9 , , , cord-022526-j9kg00qf 4464 10 especially especially RB cord-022526-j9kg00qf 4464 11 calcium calcium NN cord-022526-j9kg00qf 4464 12 ; ; : cord-022526-j9kg00qf 4464 13 and and CC cord-022526-j9kg00qf 4464 14 prevention prevention NN cord-022526-j9kg00qf 4464 15 of of IN cord-022526-j9kg00qf 4464 16 further further JJ cord-022526-j9kg00qf 4464 17 renal renal JJ cord-022526-j9kg00qf 4464 18 and and CC cord-022526-j9kg00qf 4464 19 urinary urinary JJ cord-022526-j9kg00qf 4464 20 tract tract NN cord-022526-j9kg00qf 4464 21 damage damage NN cord-022526-j9kg00qf 4464 22 is be VBZ cord-022526-j9kg00qf 4464 23 important important JJ cord-022526-j9kg00qf 4464 24 . . . cord-022526-j9kg00qf 4465 1 183 183 CD cord-022526-j9kg00qf 4466 1 , , , cord-022526-j9kg00qf 4466 2 187 187 CD cord-022526-j9kg00qf 4466 3 Diuresis Diuresis NNP cord-022526-j9kg00qf 4466 4 by by IN cord-022526-j9kg00qf 4466 5 intravenous intravenous JJ cord-022526-j9kg00qf 4466 6 fluid fluid JJ cord-022526-j9kg00qf 4466 7 administration administration NN cord-022526-j9kg00qf 4466 8 is be VBZ cord-022526-j9kg00qf 4466 9 often often RB cord-022526-j9kg00qf 4466 10 sufficient sufficient JJ cord-022526-j9kg00qf 4466 11 to to TO cord-022526-j9kg00qf 4466 12 prevent prevent VB cord-022526-j9kg00qf 4466 13 renal renal JJ cord-022526-j9kg00qf 4466 14 failure failure NN cord-022526-j9kg00qf 4466 15 . . . cord-022526-j9kg00qf 4467 1 Furosemide Furosemide NNP cord-022526-j9kg00qf 4467 2 often often RB cord-022526-j9kg00qf 4467 3 is be VBZ cord-022526-j9kg00qf 4467 4 administered administer VBN cord-022526-j9kg00qf 4467 5 after after IN cord-022526-j9kg00qf 4467 6 rehydration rehydration NN cord-022526-j9kg00qf 4467 7 of of IN cord-022526-j9kg00qf 4467 8 the the DT cord-022526-j9kg00qf 4467 9 patient patient NN cord-022526-j9kg00qf 4467 10 to to TO cord-022526-j9kg00qf 4467 11 further further RB cord-022526-j9kg00qf 4467 12 promote promote VB cord-022526-j9kg00qf 4467 13 diuresis diuresis NN cord-022526-j9kg00qf 4467 14 and and CC cord-022526-j9kg00qf 4467 15 to to TO cord-022526-j9kg00qf 4467 16 decrease decrease VB cord-022526-j9kg00qf 4467 17 the the DT cord-022526-j9kg00qf 4467 18 concentration concentration NN cord-022526-j9kg00qf 4467 19 of of IN cord-022526-j9kg00qf 4467 20 the the DT cord-022526-j9kg00qf 4467 21 toxin toxin NN cord-022526-j9kg00qf 4467 22 in in IN cord-022526-j9kg00qf 4467 23 the the DT cord-022526-j9kg00qf 4467 24 urine urine NN cord-022526-j9kg00qf 4467 25 , , , cord-022526-j9kg00qf 4467 26 which which WDT cord-022526-j9kg00qf 4467 27 may may MD cord-022526-j9kg00qf 4467 28 ameliorate ameliorate VB cord-022526-j9kg00qf 4467 29 some some DT cord-022526-j9kg00qf 4467 30 of of IN cord-022526-j9kg00qf 4467 31 the the DT cord-022526-j9kg00qf 4467 32 effects effect NNS cord-022526-j9kg00qf 4467 33 on on IN cord-022526-j9kg00qf 4467 34 the the DT cord-022526-j9kg00qf 4467 35 urinary urinary JJ cord-022526-j9kg00qf 4467 36 tract tract NN cord-022526-j9kg00qf 4467 37 mucosa mucosa NN cord-022526-j9kg00qf 4467 38 . . . cord-022526-j9kg00qf 4468 1 Diuresis Diuresis NNP cord-022526-j9kg00qf 4468 2 also also RB cord-022526-j9kg00qf 4468 3 has have VBZ cord-022526-j9kg00qf 4468 4 been be VBN cord-022526-j9kg00qf 4468 5 suggested suggest VBN cord-022526-j9kg00qf 4468 6 to to TO cord-022526-j9kg00qf 4468 7 increase increase VB cord-022526-j9kg00qf 4468 8 clearance clearance NN cord-022526-j9kg00qf 4468 9 of of IN cord-022526-j9kg00qf 4468 10 the the DT cord-022526-j9kg00qf 4468 11 toxin toxin NN cord-022526-j9kg00qf 4468 12 , , , cord-022526-j9kg00qf 4468 13 but but CC cord-022526-j9kg00qf 4468 14 no no DT cord-022526-j9kg00qf 4468 15 evidence evidence NN cord-022526-j9kg00qf 4468 16 for for IN cord-022526-j9kg00qf 4468 17 this this DT cord-022526-j9kg00qf 4468 18 has have VBZ cord-022526-j9kg00qf 4468 19 been be VBN cord-022526-j9kg00qf 4468 20 found find VBN cord-022526-j9kg00qf 4468 21 . . . cord-022526-j9kg00qf 4469 1 Judicious judicious JJ cord-022526-j9kg00qf 4469 2 use use NN cord-022526-j9kg00qf 4469 3 of of IN cord-022526-j9kg00qf 4469 4 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4469 5 may may MD cord-022526-j9kg00qf 4469 6 be be VB cord-022526-j9kg00qf 4469 7 necessary necessary JJ cord-022526-j9kg00qf 4469 8 to to TO cord-022526-j9kg00qf 4469 9 control control VB cord-022526-j9kg00qf 4469 10 abdominal abdominal JJ cord-022526-j9kg00qf 4469 11 pain pain NN cord-022526-j9kg00qf 4469 12 but but CC cord-022526-j9kg00qf 4469 13 should should MD cord-022526-j9kg00qf 4469 14 be be VB cord-022526-j9kg00qf 4469 15 reserved reserve VBN cord-022526-j9kg00qf 4469 16 until until IN cord-022526-j9kg00qf 4469 17 the the DT cord-022526-j9kg00qf 4469 18 patient patient NN cord-022526-j9kg00qf 4469 19 is be VBZ cord-022526-j9kg00qf 4469 20 rehydrated rehydrate VBN cord-022526-j9kg00qf 4469 21 and and CC cord-022526-j9kg00qf 4469 22 renal renal JJ cord-022526-j9kg00qf 4469 23 failure failure NN cord-022526-j9kg00qf 4469 24 has have VBZ cord-022526-j9kg00qf 4469 25 been be VBN cord-022526-j9kg00qf 4469 26 ruled rule VBN cord-022526-j9kg00qf 4469 27 out out RP cord-022526-j9kg00qf 4469 28 . . . cord-022526-j9kg00qf 4470 1 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 4470 2 is be VBZ cord-022526-j9kg00qf 4470 3 lipid lipid NN cord-022526-j9kg00qf 4470 4 - - HYPH cord-022526-j9kg00qf 4470 5 soluble soluble JJ cord-022526-j9kg00qf 4470 6 ; ; : cord-022526-j9kg00qf 4470 7 therefore therefore RB cord-022526-j9kg00qf 4470 8 oral oral JJ cord-022526-j9kg00qf 4470 9 administration administration NN cord-022526-j9kg00qf 4470 10 of of IN cord-022526-j9kg00qf 4470 11 mineral mineral NNP cord-022526-j9kg00qf 4470 12 oil oil NN cord-022526-j9kg00qf 4470 13 may may MD cord-022526-j9kg00qf 4470 14 prevent prevent VB cord-022526-j9kg00qf 4470 15 further further JJ cord-022526-j9kg00qf 4470 16 absorption absorption NN cord-022526-j9kg00qf 4470 17 of of IN cord-022526-j9kg00qf 4470 18 the the DT cord-022526-j9kg00qf 4470 19 toxin toxin NN cord-022526-j9kg00qf 4470 20 . . . cord-022526-j9kg00qf 4471 1 183 183 CD cord-022526-j9kg00qf 4471 2 Activated activate VBN cord-022526-j9kg00qf 4471 3 charcoal charcoal NN cord-022526-j9kg00qf 4471 4 often often RB cord-022526-j9kg00qf 4471 5 is be VBZ cord-022526-j9kg00qf 4471 6 administered administer VBN cord-022526-j9kg00qf 4471 7 with with IN cord-022526-j9kg00qf 4471 8 the the DT cord-022526-j9kg00qf 4471 9 mineral mineral NN cord-022526-j9kg00qf 4471 10 oil oil NN cord-022526-j9kg00qf 4471 11 . . . cord-022526-j9kg00qf 4472 1 To to TO cord-022526-j9kg00qf 4472 2 reduce reduce VB cord-022526-j9kg00qf 4472 3 arsenic arsenic NN cord-022526-j9kg00qf 4472 4 absorption absorption NN cord-022526-j9kg00qf 4472 5 , , , cord-022526-j9kg00qf 4472 6 one one PRP cord-022526-j9kg00qf 4472 7 should should MD cord-022526-j9kg00qf 4472 8 initiate initiate VB cord-022526-j9kg00qf 4472 9 administration administration NN cord-022526-j9kg00qf 4472 10 of of IN cord-022526-j9kg00qf 4472 11 cathartics cathartic NNS cord-022526-j9kg00qf 4472 12 such such JJ cord-022526-j9kg00qf 4472 13 as as IN cord-022526-j9kg00qf 4472 14 mineral mineral NN cord-022526-j9kg00qf 4472 15 oil oil NN cord-022526-j9kg00qf 4472 16 and and CC cord-022526-j9kg00qf 4472 17 magnesium magnesium NN cord-022526-j9kg00qf 4472 18 sulfate sulfate NN cord-022526-j9kg00qf 4472 19 slurries slurry NNS cord-022526-j9kg00qf 4472 20 and and CC cord-022526-j9kg00qf 4472 21 activated activate VBN cord-022526-j9kg00qf 4472 22 charcoal charcoal NN cord-022526-j9kg00qf 4472 23 by by IN cord-022526-j9kg00qf 4472 24 nasogastric nasogastric NN cord-022526-j9kg00qf 4472 25 tube tube NN cord-022526-j9kg00qf 4472 26 immediately immediately RB cord-022526-j9kg00qf 4472 27 . . . cord-022526-j9kg00qf 4473 1 Chelation chelation NN cord-022526-j9kg00qf 4473 2 therapy therapy NN cord-022526-j9kg00qf 4473 3 with with IN cord-022526-j9kg00qf 4473 4 sodium sodium NN cord-022526-j9kg00qf 4473 5 thiosulfate thiosulfate NN cord-022526-j9kg00qf 4473 6 20 20 CD cord-022526-j9kg00qf 4473 7 to to TO cord-022526-j9kg00qf 4473 8 30 30 CD cord-022526-j9kg00qf 4473 9 g g NN cord-022526-j9kg00qf 4473 10 in in IN cord-022526-j9kg00qf 4473 11 300 300 CD cord-022526-j9kg00qf 4473 12 ml ml NNS cord-022526-j9kg00qf 4473 13 of of IN cord-022526-j9kg00qf 4473 14 water water NN cord-022526-j9kg00qf 4473 15 orally orally RB cord-022526-j9kg00qf 4473 16 and and CC cord-022526-j9kg00qf 4473 17 dimercaprol dimercaprol NNP cord-022526-j9kg00qf 4473 18 ( ( -LRB- cord-022526-j9kg00qf 4473 19 BAL bal NN cord-022526-j9kg00qf 4473 20 ) ) -RRB- cord-022526-j9kg00qf 4474 1 3 3 LS cord-022526-j9kg00qf 4475 1 mg mg NNP cord-022526-j9kg00qf 4475 2 / / SYM cord-022526-j9kg00qf 4475 3 kg kg NNP cord-022526-j9kg00qf 4475 4 intramuscularly intramuscularly RB cord-022526-j9kg00qf 4475 5 every every DT cord-022526-j9kg00qf 4475 6 4 4 CD cord-022526-j9kg00qf 4475 7 hours hour NNS cord-022526-j9kg00qf 4475 8 is be VBZ cord-022526-j9kg00qf 4475 9 indicated indicate VBN cord-022526-j9kg00qf 4475 10 . . . cord-022526-j9kg00qf 4476 1 188 188 CD cord-022526-j9kg00qf 4476 2 Dimercaprol Dimercaprol NNP cord-022526-j9kg00qf 4476 3 is be VBZ cord-022526-j9kg00qf 4476 4 a a DT cord-022526-j9kg00qf 4476 5 specific specific JJ cord-022526-j9kg00qf 4476 6 antidote antidote NN cord-022526-j9kg00qf 4476 7 for for IN cord-022526-j9kg00qf 4476 8 trivalent trivalent JJ cord-022526-j9kg00qf 4476 9 arsenicals arsenical NNS cord-022526-j9kg00qf 4476 10 , , , cord-022526-j9kg00qf 4476 11 but but CC cord-022526-j9kg00qf 4476 12 its -PRON- PRP$ cord-022526-j9kg00qf 4476 13 efficacy efficacy NN cord-022526-j9kg00qf 4476 14 in in IN cord-022526-j9kg00qf 4476 15 horses horse NNS cord-022526-j9kg00qf 4476 16 is be VBZ cord-022526-j9kg00qf 4476 17 questionable questionable JJ cord-022526-j9kg00qf 4476 18 . . . cord-022526-j9kg00qf 4477 1 Intravenous intravenous JJ cord-022526-j9kg00qf 4477 2 fluid fluid JJ cord-022526-j9kg00qf 4477 3 administration administration NN cord-022526-j9kg00qf 4477 4 may may MD cord-022526-j9kg00qf 4477 5 help help VB cord-022526-j9kg00qf 4477 6 treat treat VB cord-022526-j9kg00qf 4477 7 shock shock NN cord-022526-j9kg00qf 4477 8 , , , cord-022526-j9kg00qf 4477 9 replace replace VB cord-022526-j9kg00qf 4477 10 fluid fluid NN cord-022526-j9kg00qf 4477 11 lost lose VBN cord-022526-j9kg00qf 4477 12 in in IN cord-022526-j9kg00qf 4477 13 feces fece NNS cord-022526-j9kg00qf 4477 14 , , , cord-022526-j9kg00qf 4477 15 and and CC cord-022526-j9kg00qf 4477 16 promote promote VB cord-022526-j9kg00qf 4477 17 diuresis diuresis NN cord-022526-j9kg00qf 4477 18 but but CC cord-022526-j9kg00qf 4477 19 should should MD cord-022526-j9kg00qf 4477 20 be be VB cord-022526-j9kg00qf 4477 21 monitored monitor VBN cord-022526-j9kg00qf 4477 22 carefully carefully RB cord-022526-j9kg00qf 4477 23 because because IN cord-022526-j9kg00qf 4477 24 pulmonary pulmonary JJ cord-022526-j9kg00qf 4477 25 edema edema NN cord-022526-j9kg00qf 4477 26 is be VBZ cord-022526-j9kg00qf 4477 27 a a DT cord-022526-j9kg00qf 4477 28 frequent frequent JJ cord-022526-j9kg00qf 4477 29 complication complication NN cord-022526-j9kg00qf 4477 30 . . . cord-022526-j9kg00qf 4478 1 The the DT cord-022526-j9kg00qf 4478 2 horse horse NN cord-022526-j9kg00qf 4478 3 may may MD cord-022526-j9kg00qf 4478 4 require require VB cord-022526-j9kg00qf 4478 5 more more RBR cord-022526-j9kg00qf 4478 6 specific specific JJ cord-022526-j9kg00qf 4478 7 treatment treatment NN cord-022526-j9kg00qf 4478 8 of of IN cord-022526-j9kg00qf 4478 9 renal renal JJ cord-022526-j9kg00qf 4478 10 , , , cord-022526-j9kg00qf 4478 11 cardiac cardiac JJ cord-022526-j9kg00qf 4478 12 , , , cord-022526-j9kg00qf 4478 13 pulmonary pulmonary JJ cord-022526-j9kg00qf 4478 14 , , , cord-022526-j9kg00qf 4478 15 or or CC cord-022526-j9kg00qf 4478 16 neurologic neurologic JJ cord-022526-j9kg00qf 4478 17 disease disease NN cord-022526-j9kg00qf 4478 18 . . . cord-022526-j9kg00qf 4479 1 Treatment treatment NN cord-022526-j9kg00qf 4479 2 of of IN cord-022526-j9kg00qf 4479 3 intestinal intestinal JJ cord-022526-j9kg00qf 4479 4 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 4479 5 is be VBZ cord-022526-j9kg00qf 4479 6 in in IN cord-022526-j9kg00qf 4479 7 principle principle NN cord-022526-j9kg00qf 4479 8 similar similar JJ cord-022526-j9kg00qf 4479 9 to to IN cord-022526-j9kg00qf 4479 10 treatment treatment NN cord-022526-j9kg00qf 4479 11 of of IN cord-022526-j9kg00qf 4479 12 other other JJ cord-022526-j9kg00qf 4479 13 forms form NNS cord-022526-j9kg00qf 4479 14 of of IN cord-022526-j9kg00qf 4479 15 colitis colitis NN cord-022526-j9kg00qf 4479 16 but but CC cord-022526-j9kg00qf 4479 17 is be VBZ cord-022526-j9kg00qf 4479 18 often often RB cord-022526-j9kg00qf 4479 19 unsuccessful unsuccessful JJ cord-022526-j9kg00qf 4479 20 because because IN cord-022526-j9kg00qf 4479 21 of of IN cord-022526-j9kg00qf 4479 22 the the DT cord-022526-j9kg00qf 4479 23 rapidly rapidly RB cord-022526-j9kg00qf 4479 24 progressive progressive JJ cord-022526-j9kg00qf 4479 25 nature nature NN cord-022526-j9kg00qf 4479 26 of of IN cord-022526-j9kg00qf 4479 27 the the DT cord-022526-j9kg00qf 4479 28 syndrome syndrome NN cord-022526-j9kg00qf 4479 29 . . . cord-022526-j9kg00qf 4480 1 Inclusion inclusion NN cord-022526-j9kg00qf 4480 2 of of IN cord-022526-j9kg00qf 4480 3 heparin heparin NN cord-022526-j9kg00qf 4480 4 in in IN cord-022526-j9kg00qf 4480 5 intravenous intravenous JJ cord-022526-j9kg00qf 4480 6 fluids fluid NNS cord-022526-j9kg00qf 4480 7 ( ( -LRB- cord-022526-j9kg00qf 4480 8 20 20 CD cord-022526-j9kg00qf 4480 9 to to TO cord-022526-j9kg00qf 4480 10 80 80 CD cord-022526-j9kg00qf 4480 11 IU IU NNP cord-022526-j9kg00qf 4480 12 / / SYM cord-022526-j9kg00qf 4480 13 kg kg CC cord-022526-j9kg00qf 4480 14 intravenously intravenously RB cord-022526-j9kg00qf 4480 15 every every DT cord-022526-j9kg00qf 4480 16 8 8 CD cord-022526-j9kg00qf 4480 17 to to TO cord-022526-j9kg00qf 4480 18 12 12 CD cord-022526-j9kg00qf 4480 19 hours hour NNS cord-022526-j9kg00qf 4480 20 ) ) -RRB- cord-022526-j9kg00qf 4480 21 may may MD cord-022526-j9kg00qf 4480 22 help help VB cord-022526-j9kg00qf 4480 23 prevent prevent VB cord-022526-j9kg00qf 4480 24 vascular vascular JJ cord-022526-j9kg00qf 4480 25 thrombosis thrombosis NN cord-022526-j9kg00qf 4480 26 . . . cord-022526-j9kg00qf 4481 1 Administration administration NN cord-022526-j9kg00qf 4481 2 of of IN cord-022526-j9kg00qf 4481 3 hypertonic hypertonic JJ cord-022526-j9kg00qf 4481 4 saline saline NN cord-022526-j9kg00qf 4481 5 solutions solution NNS cord-022526-j9kg00qf 4481 6 or or CC cord-022526-j9kg00qf 4481 7 colloids colloid NNS cord-022526-j9kg00qf 4481 8 may may MD cord-022526-j9kg00qf 4481 9 prove prove VB cord-022526-j9kg00qf 4481 10 to to TO cord-022526-j9kg00qf 4481 11 be be VB cord-022526-j9kg00qf 4481 12 useful useful JJ cord-022526-j9kg00qf 4481 13 during during IN cord-022526-j9kg00qf 4481 14 initial initial JJ cord-022526-j9kg00qf 4481 15 periods period NNS cord-022526-j9kg00qf 4481 16 of of IN cord-022526-j9kg00qf 4481 17 shock shock NN cord-022526-j9kg00qf 4481 18 . . . cord-022526-j9kg00qf 4482 1 Early early JJ cord-022526-j9kg00qf 4482 2 treatment treatment NN cord-022526-j9kg00qf 4482 3 with with IN cord-022526-j9kg00qf 4482 4 prednisolone prednisolone NNP cord-022526-j9kg00qf 4482 5 succinate succinate NNP cord-022526-j9kg00qf 4482 6 ( ( -LRB- cord-022526-j9kg00qf 4482 7 10 10 CD cord-022526-j9kg00qf 4482 8 to to TO cord-022526-j9kg00qf 4482 9 20 20 CD cord-022526-j9kg00qf 4482 10 mg mg NN cord-022526-j9kg00qf 4482 11 / / SYM cord-022526-j9kg00qf 4482 12 kg kg NNP cord-022526-j9kg00qf 4482 13 intravenously intravenously RB cord-022526-j9kg00qf 4482 14 ) ) -RRB- cord-022526-j9kg00qf 4482 15 or or CC cord-022526-j9kg00qf 4482 16 dexamethasone dexamethasone NN cord-022526-j9kg00qf 4482 17 ( ( -LRB- cord-022526-j9kg00qf 4482 18 0.1 0.1 CD cord-022526-j9kg00qf 4482 19 to to TO cord-022526-j9kg00qf 4482 20 0.2 0.2 CD cord-022526-j9kg00qf 4482 21 mg mg NN cord-022526-j9kg00qf 4482 22 / / SYM cord-022526-j9kg00qf 4482 23 kg kg NNP cord-022526-j9kg00qf 4482 24 intravenously intravenously RB cord-022526-j9kg00qf 4482 25 ) ) -RRB- cord-022526-j9kg00qf 4482 26 may may MD cord-022526-j9kg00qf 4482 27 be be VB cord-022526-j9kg00qf 4482 28 essential essential JJ cord-022526-j9kg00qf 4482 29 for for IN cord-022526-j9kg00qf 4482 30 successful successful JJ cord-022526-j9kg00qf 4482 31 treatment treatment NN cord-022526-j9kg00qf 4482 32 . . . cord-022526-j9kg00qf 4483 1 192 192 CD cord-022526-j9kg00qf 4484 1 Mild mild JJ cord-022526-j9kg00qf 4484 2 cases case NNS cord-022526-j9kg00qf 4484 3 of of IN cord-022526-j9kg00qf 4484 4 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4484 5 overload overload NN cord-022526-j9kg00qf 4484 6 may may MD cord-022526-j9kg00qf 4484 7 not not RB cord-022526-j9kg00qf 4484 8 require require VB cord-022526-j9kg00qf 4484 9 treatment treatment NN cord-022526-j9kg00qf 4484 10 other other JJ cord-022526-j9kg00qf 4484 11 than than IN cord-022526-j9kg00qf 4484 12 exclusion exclusion NN cord-022526-j9kg00qf 4484 13 of of IN cord-022526-j9kg00qf 4484 14 grains grain NNS cord-022526-j9kg00qf 4484 15 from from IN cord-022526-j9kg00qf 4484 16 the the DT cord-022526-j9kg00qf 4484 17 diet diet NN cord-022526-j9kg00qf 4484 18 for for IN cord-022526-j9kg00qf 4484 19 several several JJ cord-022526-j9kg00qf 4484 20 days day NNS cord-022526-j9kg00qf 4484 21 to to IN cord-022526-j9kg00qf 4484 22 weeks week NNS cord-022526-j9kg00qf 4484 23 and and CC cord-022526-j9kg00qf 4484 24 gradual gradual JJ cord-022526-j9kg00qf 4484 25 reintroduction reintroduction NN cord-022526-j9kg00qf 4484 26 of of IN cord-022526-j9kg00qf 4484 27 grain grain NN cord-022526-j9kg00qf 4484 28 into into IN cord-022526-j9kg00qf 4484 29 the the DT cord-022526-j9kg00qf 4484 30 diet diet NN cord-022526-j9kg00qf 4484 31 later later RB cord-022526-j9kg00qf 4484 32 if if IN cord-022526-j9kg00qf 4484 33 the the DT cord-022526-j9kg00qf 4484 34 horse horse NN cord-022526-j9kg00qf 4484 35 needs need VBZ cord-022526-j9kg00qf 4484 36 the the DT cord-022526-j9kg00qf 4484 37 extra extra JJ cord-022526-j9kg00qf 4484 38 energy energy NN cord-022526-j9kg00qf 4484 39 . . . cord-022526-j9kg00qf 4485 1 Patients patient NNS cord-022526-j9kg00qf 4485 2 showing show VBG cord-022526-j9kg00qf 4485 3 signs sign NNS cord-022526-j9kg00qf 4485 4 of of IN cord-022526-j9kg00qf 4485 5 colic colic NN cord-022526-j9kg00qf 4485 6 or or CC cord-022526-j9kg00qf 4485 7 diarrhea diarrhea NN cord-022526-j9kg00qf 4485 8 without without IN cord-022526-j9kg00qf 4485 9 other other JJ cord-022526-j9kg00qf 4485 10 systemic systemic JJ cord-022526-j9kg00qf 4485 11 signs sign NNS cord-022526-j9kg00qf 4485 12 may may MD cord-022526-j9kg00qf 4485 13 benefit benefit VB cord-022526-j9kg00qf 4485 14 from from IN cord-022526-j9kg00qf 4485 15 administration administration NN cord-022526-j9kg00qf 4485 16 of of IN cord-022526-j9kg00qf 4485 17 mineral mineral NNP cord-022526-j9kg00qf 4485 18 oil oil NN cord-022526-j9kg00qf 4485 19 , , , cord-022526-j9kg00qf 4485 20 charcoal charcoal NN cord-022526-j9kg00qf 4485 21 , , , cord-022526-j9kg00qf 4485 22 and and CC cord-022526-j9kg00qf 4485 23 fluids fluid NNS cord-022526-j9kg00qf 4485 24 via via IN cord-022526-j9kg00qf 4485 25 nasogastric nasogastric NN cord-022526-j9kg00qf 4485 26 tube tube NN cord-022526-j9kg00qf 4485 27 . . . cord-022526-j9kg00qf 4486 1 One one CD cord-022526-j9kg00qf 4486 2 also also RB cord-022526-j9kg00qf 4486 3 may may MD cord-022526-j9kg00qf 4486 4 lavage lavage VB cord-022526-j9kg00qf 4486 5 residual residual JJ cord-022526-j9kg00qf 4486 6 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4486 7 from from IN cord-022526-j9kg00qf 4486 8 the the DT cord-022526-j9kg00qf 4486 9 stomach stomach NN cord-022526-j9kg00qf 4486 10 with with IN cord-022526-j9kg00qf 4486 11 the the DT cord-022526-j9kg00qf 4486 12 nasogastric nasogastric NN cord-022526-j9kg00qf 4486 13 tube tube NN cord-022526-j9kg00qf 4486 14 . . . cord-022526-j9kg00qf 4487 1 NSAIDs nsaid NNS cord-022526-j9kg00qf 4487 2 such such JJ cord-022526-j9kg00qf 4487 3 as as IN cord-022526-j9kg00qf 4487 4 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4487 5 ( ( -LRB- cord-022526-j9kg00qf 4487 6 2.2 2.2 CD cord-022526-j9kg00qf 4487 7 to to TO cord-022526-j9kg00qf 4487 8 4.4 4.4 CD cord-022526-j9kg00qf 4487 9 mg mg NNP cord-022526-j9kg00qf 4487 10 / / SYM cord-022526-j9kg00qf 4487 11 kg kg NNP cord-022526-j9kg00qf 4487 12 / / SYM cord-022526-j9kg00qf 4487 13 day day NN cord-022526-j9kg00qf 4487 14 intravenously intravenously RB cord-022526-j9kg00qf 4487 15 ) ) -RRB- cord-022526-j9kg00qf 4487 16 or or CC cord-022526-j9kg00qf 4487 17 flunixin flunixin NNP cord-022526-j9kg00qf 4487 18 meglumine meglumine NNP cord-022526-j9kg00qf 4487 19 ( ( -LRB- cord-022526-j9kg00qf 4487 20 1 1 CD cord-022526-j9kg00qf 4487 21 mg mg NNP cord-022526-j9kg00qf 4487 22 / / SYM cord-022526-j9kg00qf 4487 23 kg kg XX cord-022526-j9kg00qf 4487 24 intravenously intravenously RB cord-022526-j9kg00qf 4487 25 every every DT cord-022526-j9kg00qf 4487 26 12 12 CD cord-022526-j9kg00qf 4487 27 hours hour NNS cord-022526-j9kg00qf 4487 28 ) ) -RRB- cord-022526-j9kg00qf 4487 29 often often RB cord-022526-j9kg00qf 4487 30 are be VBP cord-022526-j9kg00qf 4487 31 administered administer VBN cord-022526-j9kg00qf 4487 32 to to TO cord-022526-j9kg00qf 4487 33 prevent prevent VB cord-022526-j9kg00qf 4487 34 laminitis laminitis NN cord-022526-j9kg00qf 4487 35 . . . cord-022526-j9kg00qf 4488 1 Phenoxybenzamine Phenoxybenzamine NNP cord-022526-j9kg00qf 4488 2 and and CC cord-022526-j9kg00qf 4488 3 heparin heparin NN cord-022526-j9kg00qf 4488 4 given give VBN cord-022526-j9kg00qf 4488 5 before before IN cord-022526-j9kg00qf 4488 6 the the DT cord-022526-j9kg00qf 4488 7 onset onset NN cord-022526-j9kg00qf 4488 8 of of IN cord-022526-j9kg00qf 4488 9 laminitis laminitis NN cord-022526-j9kg00qf 4488 10 may may MD cord-022526-j9kg00qf 4488 11 prevent prevent VB cord-022526-j9kg00qf 4488 12 or or CC cord-022526-j9kg00qf 4488 13 decrease decrease VB cord-022526-j9kg00qf 4488 14 the the DT cord-022526-j9kg00qf 4488 15 severity severity NN cord-022526-j9kg00qf 4488 16 of of IN cord-022526-j9kg00qf 4488 17 laminitis laminitis NN cord-022526-j9kg00qf 4488 18 . . . cord-022526-j9kg00qf 4489 1 238 238 CD cord-022526-j9kg00qf 4489 2 , , , cord-022526-j9kg00qf 4489 3 248 248 CD cord-022526-j9kg00qf 4489 4 More More JJR cord-022526-j9kg00qf 4489 5 severe severe JJ cord-022526-j9kg00qf 4489 6 cases case NNS cord-022526-j9kg00qf 4489 7 with with IN cord-022526-j9kg00qf 4489 8 dehydrating dehydrate VBG cord-022526-j9kg00qf 4489 9 diarrhea diarrhea NN cord-022526-j9kg00qf 4489 10 , , , cord-022526-j9kg00qf 4489 11 systemic systemic JJ cord-022526-j9kg00qf 4489 12 signs sign NNS cord-022526-j9kg00qf 4489 13 of of IN cord-022526-j9kg00qf 4489 14 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4489 15 , , , cord-022526-j9kg00qf 4489 16 or or CC cord-022526-j9kg00qf 4489 17 metabolic metabolic JJ cord-022526-j9kg00qf 4489 18 acidosis acidosis NN cord-022526-j9kg00qf 4489 19 require require VBP cord-022526-j9kg00qf 4489 20 intravenous intravenous JJ cord-022526-j9kg00qf 4489 21 fluid fluid NN cord-022526-j9kg00qf 4489 22 support support NN cord-022526-j9kg00qf 4489 23 to to TO cord-022526-j9kg00qf 4489 24 maintain maintain VB cord-022526-j9kg00qf 4489 25 water water NN cord-022526-j9kg00qf 4489 26 , , , cord-022526-j9kg00qf 4489 27 electrolyte electrolyte NN cord-022526-j9kg00qf 4489 28 , , , cord-022526-j9kg00qf 4489 29 and and CC cord-022526-j9kg00qf 4489 30 acid acid NN cord-022526-j9kg00qf 4489 31 - - HYPH cord-022526-j9kg00qf 4489 32 base base NN cord-022526-j9kg00qf 4489 33 balance balance NN cord-022526-j9kg00qf 4489 34 in in IN cord-022526-j9kg00qf 4489 35 addition addition NN cord-022526-j9kg00qf 4489 36 to to IN cord-022526-j9kg00qf 4489 37 the the DT cord-022526-j9kg00qf 4489 38 previously previously RB cord-022526-j9kg00qf 4489 39 mentioned mention VBN cord-022526-j9kg00qf 4489 40 treatments treatment NNS cord-022526-j9kg00qf 4489 41 . . . cord-022526-j9kg00qf 4490 1 Large large JJ cord-022526-j9kg00qf 4490 2 amounts amount NNS cord-022526-j9kg00qf 4490 3 of of IN cord-022526-j9kg00qf 4490 4 bicarbonatecontaining bicarbonatecontaining NN cord-022526-j9kg00qf 4490 5 solutions solution NNS cord-022526-j9kg00qf 4490 6 may may MD cord-022526-j9kg00qf 4490 7 be be VB cord-022526-j9kg00qf 4490 8 required require VBN cord-022526-j9kg00qf 4490 9 . . . cord-022526-j9kg00qf 4491 1 One one PRP cord-022526-j9kg00qf 4491 2 should should MD cord-022526-j9kg00qf 4491 3 take take VB cord-022526-j9kg00qf 4491 4 care care NN cord-022526-j9kg00qf 4491 5 when when WRB cord-022526-j9kg00qf 4491 6 administering administer VBG cord-022526-j9kg00qf 4491 7 hypertonic hypertonic JJ cord-022526-j9kg00qf 4491 8 bicarbonate bicarbonate NN cord-022526-j9kg00qf 4491 9 solutions solution NNS cord-022526-j9kg00qf 4491 10 , , , cord-022526-j9kg00qf 4491 11 because because IN cord-022526-j9kg00qf 4491 12 many many JJ cord-022526-j9kg00qf 4491 13 patients patient NNS cord-022526-j9kg00qf 4491 14 already already RB cord-022526-j9kg00qf 4491 15 may may MD cord-022526-j9kg00qf 4491 16 be be VB cord-022526-j9kg00qf 4491 17 hyperosmotic hyperosmotic JJ cord-022526-j9kg00qf 4491 18 from from IN cord-022526-j9kg00qf 4491 19 lactic lactic JJ cord-022526-j9kg00qf 4491 20 acidemia acidemia NN cord-022526-j9kg00qf 4491 21 . . . cord-022526-j9kg00qf 4492 1 Isotonic isotonic JJ cord-022526-j9kg00qf 4492 2 sodium sodium NN cord-022526-j9kg00qf 4492 3 bicarbonate bicarbonate NN cord-022526-j9kg00qf 4492 4 1.3 1.3 CD cord-022526-j9kg00qf 4492 5 % % NN cord-022526-j9kg00qf 4492 6 may may MD cord-022526-j9kg00qf 4492 7 be be VB cord-022526-j9kg00qf 4492 8 useful useful JJ cord-022526-j9kg00qf 4492 9 in in IN cord-022526-j9kg00qf 4492 10 the the DT cord-022526-j9kg00qf 4492 11 hyperosmotic hyperosmotic JJ cord-022526-j9kg00qf 4492 12 patient patient NN cord-022526-j9kg00qf 4492 13 . . . cord-022526-j9kg00qf 4493 1 Careful careful JJ cord-022526-j9kg00qf 4493 2 attention attention NN cord-022526-j9kg00qf 4493 3 to to IN cord-022526-j9kg00qf 4493 4 calcium calcium NN cord-022526-j9kg00qf 4493 5 balance balance NN cord-022526-j9kg00qf 4493 6 is be VBZ cord-022526-j9kg00qf 4493 7 also also RB cord-022526-j9kg00qf 4493 8 important important JJ cord-022526-j9kg00qf 4493 9 , , , cord-022526-j9kg00qf 4493 10 because because IN cord-022526-j9kg00qf 4493 11 severe severe JJ cord-022526-j9kg00qf 4493 12 hypocalcemia hypocalcemia NN cord-022526-j9kg00qf 4493 13 may may MD cord-022526-j9kg00qf 4493 14 occur occur VB cord-022526-j9kg00qf 4493 15 . . . cord-022526-j9kg00qf 4494 1 One one PRP cord-022526-j9kg00qf 4494 2 should should MD cord-022526-j9kg00qf 4494 3 institute institute VB cord-022526-j9kg00qf 4494 4 aggressive aggressive JJ cord-022526-j9kg00qf 4494 5 therapy therapy NN cord-022526-j9kg00qf 4494 6 for for IN cord-022526-j9kg00qf 4494 7 systemic systemic JJ cord-022526-j9kg00qf 4494 8 inflammation inflammation NN cord-022526-j9kg00qf 4494 9 from from IN cord-022526-j9kg00qf 4494 10 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4494 11 . . . cord-022526-j9kg00qf 4495 1 One one PRP cord-022526-j9kg00qf 4495 2 should should MD cord-022526-j9kg00qf 4495 3 administer administer VB cord-022526-j9kg00qf 4495 4 broad broad JJ cord-022526-j9kg00qf 4495 5 - - HYPH cord-022526-j9kg00qf 4495 6 spectrum spectrum NN cord-022526-j9kg00qf 4495 7 antibiotics antibiotic NNS cord-022526-j9kg00qf 4495 8 intravenously intravenously RB cord-022526-j9kg00qf 4495 9 to to TO cord-022526-j9kg00qf 4495 10 combat combat VB cord-022526-j9kg00qf 4495 11 bacteremia bacteremia NN cord-022526-j9kg00qf 4495 12 and and CC cord-022526-j9kg00qf 4495 13 septicemia septicemia NN cord-022526-j9kg00qf 4495 14 , , , cord-022526-j9kg00qf 4495 15 which which WDT cord-022526-j9kg00qf 4495 16 frequently frequently RB cord-022526-j9kg00qf 4495 17 complicate complicate VBP cord-022526-j9kg00qf 4495 18 colitis colitis NN cord-022526-j9kg00qf 4495 19 induced induce VBN cord-022526-j9kg00qf 4495 20 by by IN cord-022526-j9kg00qf 4495 21 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4495 22 overload overload NN cord-022526-j9kg00qf 4495 23 . . . cord-022526-j9kg00qf 4496 1 In in IN cord-022526-j9kg00qf 4496 2 extreme extreme JJ cord-022526-j9kg00qf 4496 3 cases case NNS cord-022526-j9kg00qf 4496 4 , , , cord-022526-j9kg00qf 4496 5 especially especially RB cord-022526-j9kg00qf 4496 6 if if IN cord-022526-j9kg00qf 4496 7 the the DT cord-022526-j9kg00qf 4496 8 patient patient NN cord-022526-j9kg00qf 4496 9 has have VBZ cord-022526-j9kg00qf 4496 10 ingested ingest VBN cord-022526-j9kg00qf 4496 11 a a DT cord-022526-j9kg00qf 4496 12 large large JJ cord-022526-j9kg00qf 4496 13 quantity quantity NN cord-022526-j9kg00qf 4496 14 of of IN cord-022526-j9kg00qf 4496 15 grain grain NN cord-022526-j9kg00qf 4496 16 , , , cord-022526-j9kg00qf 4496 17 surgical surgical JJ cord-022526-j9kg00qf 4496 18 removal removal NN cord-022526-j9kg00qf 4496 19 of of IN cord-022526-j9kg00qf 4496 20 the the DT cord-022526-j9kg00qf 4496 21 grain grain NN cord-022526-j9kg00qf 4496 22 from from IN cord-022526-j9kg00qf 4496 23 the the DT cord-022526-j9kg00qf 4496 24 large large JJ cord-022526-j9kg00qf 4496 25 intestine intestine NN cord-022526-j9kg00qf 4496 26 may may MD cord-022526-j9kg00qf 4496 27 be be VB cord-022526-j9kg00qf 4496 28 indicated indicate VBN cord-022526-j9kg00qf 4496 29 , , , cord-022526-j9kg00qf 4496 30 especially especially RB cord-022526-j9kg00qf 4496 31 if if IN cord-022526-j9kg00qf 4496 32 one one PRP cord-022526-j9kg00qf 4496 33 can can MD cord-022526-j9kg00qf 4496 34 accomplish accomplish VB cord-022526-j9kg00qf 4496 35 surgery surgery NN cord-022526-j9kg00qf 4496 36 before before IN cord-022526-j9kg00qf 4496 37 the the DT cord-022526-j9kg00qf 4496 38 onset onset NN cord-022526-j9kg00qf 4496 39 of of IN cord-022526-j9kg00qf 4496 40 severe severe JJ cord-022526-j9kg00qf 4496 41 clinical clinical JJ cord-022526-j9kg00qf 4496 42 signs sign NNS cord-022526-j9kg00qf 4496 43 . . . cord-022526-j9kg00qf 4497 1 However however RB cord-022526-j9kg00qf 4497 2 , , , cord-022526-j9kg00qf 4497 3 administration administration NN cord-022526-j9kg00qf 4497 4 of of IN cord-022526-j9kg00qf 4497 5 oral oral JJ cord-022526-j9kg00qf 4497 6 cathartics cathartic NNS cord-022526-j9kg00qf 4497 7 , , , cord-022526-j9kg00qf 4497 8 such such JJ cord-022526-j9kg00qf 4497 9 as as IN cord-022526-j9kg00qf 4497 10 magnesium magnesium NN cord-022526-j9kg00qf 4497 11 sulfate sulfate NN cord-022526-j9kg00qf 4497 12 slurries slurry NNS cord-022526-j9kg00qf 4497 13 or or CC cord-022526-j9kg00qf 4497 14 mineral mineral NN cord-022526-j9kg00qf 4497 15 oil oil NN cord-022526-j9kg00qf 4497 16 , , , cord-022526-j9kg00qf 4497 17 or or CC cord-022526-j9kg00qf 4497 18 a a DT cord-022526-j9kg00qf 4497 19 combination combination NN cord-022526-j9kg00qf 4497 20 of of IN cord-022526-j9kg00qf 4497 21 these these DT cord-022526-j9kg00qf 4497 22 , , , cord-022526-j9kg00qf 4497 23 is be VBZ cord-022526-j9kg00qf 4497 24 often often RB cord-022526-j9kg00qf 4497 25 sufficient sufficient JJ cord-022526-j9kg00qf 4497 26 to to TO cord-022526-j9kg00qf 4497 27 clear clear VB cord-022526-j9kg00qf 4497 28 the the DT cord-022526-j9kg00qf 4497 29 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4497 30 from from IN cord-022526-j9kg00qf 4497 31 the the DT cord-022526-j9kg00qf 4497 32 large large JJ cord-022526-j9kg00qf 4497 33 intestine intestine NN cord-022526-j9kg00qf 4497 34 before before IN cord-022526-j9kg00qf 4497 35 fermentation fermentation NN cord-022526-j9kg00qf 4497 36 , , , cord-022526-j9kg00qf 4497 37 mucosal mucosal JJ cord-022526-j9kg00qf 4497 38 damage damage NN cord-022526-j9kg00qf 4497 39 , , , cord-022526-j9kg00qf 4497 40 and and CC cord-022526-j9kg00qf 4497 41 absorption absorption NN cord-022526-j9kg00qf 4497 42 of of IN cord-022526-j9kg00qf 4497 43 endotoxin endotoxin NN cord-022526-j9kg00qf 4497 44 and and CC cord-022526-j9kg00qf 4497 45 lactic lactic JJ cord-022526-j9kg00qf 4497 46 acid acid NN cord-022526-j9kg00qf 4497 47 occur occur VBP cord-022526-j9kg00qf 4497 48 . . . cord-022526-j9kg00qf 4498 1 Oral oral JJ cord-022526-j9kg00qf 4498 2 administration administration NN cord-022526-j9kg00qf 4498 3 of of IN cord-022526-j9kg00qf 4498 4 activated activate VBN cord-022526-j9kg00qf 4498 5 charcoal charcoal NN cord-022526-j9kg00qf 4498 6 may may MD cord-022526-j9kg00qf 4498 7 prevent prevent VB cord-022526-j9kg00qf 4498 8 absorption absorption NN cord-022526-j9kg00qf 4498 9 of of IN cord-022526-j9kg00qf 4498 10 endotoxin endotoxin NN cord-022526-j9kg00qf 4498 11 by by IN cord-022526-j9kg00qf 4498 12 binding bind VBG cord-022526-j9kg00qf 4498 13 the the DT cord-022526-j9kg00qf 4498 14 molecules molecule NNS cord-022526-j9kg00qf 4498 15 in in IN cord-022526-j9kg00qf 4498 16 the the DT cord-022526-j9kg00qf 4498 17 lumen lumen NN cord-022526-j9kg00qf 4498 18 of of IN cord-022526-j9kg00qf 4498 19 the the DT cord-022526-j9kg00qf 4498 20 bowel bowel NN cord-022526-j9kg00qf 4498 21 . . . cord-022526-j9kg00qf 4499 1 In in IN cord-022526-j9kg00qf 4499 2 any any DT cord-022526-j9kg00qf 4499 3 case case NN cord-022526-j9kg00qf 4499 4 , , , cord-022526-j9kg00qf 4499 5 one one PRP cord-022526-j9kg00qf 4499 6 should should MD cord-022526-j9kg00qf 4499 7 discontinue discontinue VB cord-022526-j9kg00qf 4499 8 feeding feeding NN cord-022526-j9kg00qf 4499 9 of of IN cord-022526-j9kg00qf 4499 10 the the DT cord-022526-j9kg00qf 4499 11 source source NN cord-022526-j9kg00qf 4499 12 of of IN cord-022526-j9kg00qf 4499 13 the the DT cord-022526-j9kg00qf 4499 14 soluble soluble JJ cord-022526-j9kg00qf 4499 15 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 4499 16 , , , cord-022526-j9kg00qf 4499 17 such such JJ cord-022526-j9kg00qf 4499 18 as as IN cord-022526-j9kg00qf 4499 19 grains grain NNS cord-022526-j9kg00qf 4499 20 . . . cord-022526-j9kg00qf 4500 1 One one PRP cord-022526-j9kg00qf 4500 2 should should MD cord-022526-j9kg00qf 4500 3 feed feed VB cord-022526-j9kg00qf 4500 4 the the DT cord-022526-j9kg00qf 4500 5 horse horse NN cord-022526-j9kg00qf 4500 6 low low JJ cord-022526-j9kg00qf 4500 7 - - HYPH cord-022526-j9kg00qf 4500 8 carbohydrate carbohydrate NN cord-022526-j9kg00qf 4500 9 and and CC cord-022526-j9kg00qf 4500 10 low low JJ cord-022526-j9kg00qf 4500 11 - - HYPH cord-022526-j9kg00qf 4500 12 protein protein NN cord-022526-j9kg00qf 4500 13 roughage roughage NN cord-022526-j9kg00qf 4500 14 such such JJ cord-022526-j9kg00qf 4500 15 as as IN cord-022526-j9kg00qf 4500 16 grass grass NN cord-022526-j9kg00qf 4500 17 or or CC cord-022526-j9kg00qf 4500 18 oat oat NN cord-022526-j9kg00qf 4500 19 hays hays NNP cord-022526-j9kg00qf 4500 20 until until IN cord-022526-j9kg00qf 4500 21 the the DT cord-022526-j9kg00qf 4500 22 microbial microbial JJ cord-022526-j9kg00qf 4500 23 flora flora NNP cord-022526-j9kg00qf 4500 24 recovers recover VBZ cord-022526-j9kg00qf 4500 25 . . . cord-022526-j9kg00qf 4501 1 Oral oral JJ cord-022526-j9kg00qf 4501 2 administration administration NN cord-022526-j9kg00qf 4501 3 of of IN cord-022526-j9kg00qf 4501 4 probiotic probiotic JJ cord-022526-j9kg00qf 4501 5 preparations preparation NNS cord-022526-j9kg00qf 4501 6 containing contain VBG cord-022526-j9kg00qf 4501 7 Lactobacillus lactobacillus NN cord-022526-j9kg00qf 4501 8 is be VBZ cord-022526-j9kg00qf 4501 9 contraindicated contraindicate VBN cord-022526-j9kg00qf 4501 10 ; ; : cord-022526-j9kg00qf 4501 11 however however RB cord-022526-j9kg00qf 4501 12 , , , cord-022526-j9kg00qf 4501 13 other other JJ cord-022526-j9kg00qf 4501 14 sources source NNS cord-022526-j9kg00qf 4501 15 of of IN cord-022526-j9kg00qf 4501 16 normal normal JJ cord-022526-j9kg00qf 4501 17 equine equine JJ cord-022526-j9kg00qf 4501 18 large large JJ cord-022526-j9kg00qf 4501 19 intestinal intestinal JJ cord-022526-j9kg00qf 4501 20 microbial microbial JJ cord-022526-j9kg00qf 4501 21 flora flora NNS cord-022526-j9kg00qf 4501 22 , , , cord-022526-j9kg00qf 4501 23 such such JJ cord-022526-j9kg00qf 4501 24 as as IN cord-022526-j9kg00qf 4501 25 fecal fecal JJ cord-022526-j9kg00qf 4501 26 extracts extract NNS cord-022526-j9kg00qf 4501 27 from from IN cord-022526-j9kg00qf 4501 28 normal normal JJ cord-022526-j9kg00qf 4501 29 feces fece NNS cord-022526-j9kg00qf 4501 30 , , , cord-022526-j9kg00qf 4501 31 may may MD cord-022526-j9kg00qf 4501 32 be be VB cord-022526-j9kg00qf 4501 33 useful useful JJ cord-022526-j9kg00qf 4501 34 to to TO cord-022526-j9kg00qf 4501 35 reintroduce reintroduce VB cord-022526-j9kg00qf 4501 36 appropriate appropriate JJ cord-022526-j9kg00qf 4501 37 microorganisms microorganism NNS cord-022526-j9kg00qf 4501 38 . . . cord-022526-j9kg00qf 4502 1 Complications complication NNS cord-022526-j9kg00qf 4502 2 from from IN cord-022526-j9kg00qf 4502 3 laminitis laminitis NN cord-022526-j9kg00qf 4502 4 and and CC cord-022526-j9kg00qf 4502 5 sepsis sepsis NN cord-022526-j9kg00qf 4502 6 are be VBP cord-022526-j9kg00qf 4502 7 common common JJ cord-022526-j9kg00qf 4502 8 and and CC cord-022526-j9kg00qf 4502 9 often often RB cord-022526-j9kg00qf 4502 10 cause cause VBP cord-022526-j9kg00qf 4502 11 death death NN cord-022526-j9kg00qf 4502 12 . . . cord-022526-j9kg00qf 4503 1 Treatment treatment NN cord-022526-j9kg00qf 4503 2 of of IN cord-022526-j9kg00qf 4503 3 sand sand NN cord-022526-j9kg00qf 4503 4 enteropathy enteropathy NNP cord-022526-j9kg00qf 4503 5 requires require VBZ cord-022526-j9kg00qf 4503 6 removal removal NN cord-022526-j9kg00qf 4503 7 of of IN cord-022526-j9kg00qf 4503 8 the the DT cord-022526-j9kg00qf 4503 9 sand sand NN cord-022526-j9kg00qf 4503 10 from from IN cord-022526-j9kg00qf 4503 11 the the DT cord-022526-j9kg00qf 4503 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4503 13 tract tract NN cord-022526-j9kg00qf 4503 14 using use VBG cord-022526-j9kg00qf 4503 15 psyllium psyllium NN cord-022526-j9kg00qf 4503 16 products product NNS cord-022526-j9kg00qf 4503 17 and and CC cord-022526-j9kg00qf 4503 18 magnesium magnesium NN cord-022526-j9kg00qf 4503 19 sulfate sulfate NN cord-022526-j9kg00qf 4503 20 slurries slurry NNS cord-022526-j9kg00qf 4503 21 administered administer VBD cord-022526-j9kg00qf 4503 22 orally orally RB cord-022526-j9kg00qf 4503 23 . . . cord-022526-j9kg00qf 4504 1 Analgesics analgesic NNS cord-022526-j9kg00qf 4504 2 may may MD cord-022526-j9kg00qf 4504 3 be be VB cord-022526-j9kg00qf 4504 4 required require VBN cord-022526-j9kg00qf 4504 5 initially initially RB cord-022526-j9kg00qf 4504 6 to to TO cord-022526-j9kg00qf 4504 7 relieve relieve VB cord-022526-j9kg00qf 4504 8 pain pain NN cord-022526-j9kg00qf 4504 9 and and CC cord-022526-j9kg00qf 4504 10 stimulate stimulate VB cord-022526-j9kg00qf 4504 11 appetite appetite NN cord-022526-j9kg00qf 4504 12 . . . cord-022526-j9kg00qf 4505 1 A a DT cord-022526-j9kg00qf 4505 2 diet diet NN cord-022526-j9kg00qf 4505 3 high high JJ cord-022526-j9kg00qf 4505 4 in in IN cord-022526-j9kg00qf 4505 5 roughage roughage NN cord-022526-j9kg00qf 4505 6 often often RB cord-022526-j9kg00qf 4505 7 stimulates stimulate VBZ cord-022526-j9kg00qf 4505 8 further further JJ cord-022526-j9kg00qf 4505 9 passage passage NN cord-022526-j9kg00qf 4505 10 of of IN cord-022526-j9kg00qf 4505 11 sand sand NN cord-022526-j9kg00qf 4505 12 . . . cord-022526-j9kg00qf 4506 1 Treatment treatment NN cord-022526-j9kg00qf 4506 2 may may MD cord-022526-j9kg00qf 4506 3 require require VB cord-022526-j9kg00qf 4506 4 several several JJ cord-022526-j9kg00qf 4506 5 weeks week NNS cord-022526-j9kg00qf 4506 6 to to TO cord-022526-j9kg00qf 4506 7 remove remove VB cord-022526-j9kg00qf 4506 8 as as RB cord-022526-j9kg00qf 4506 9 much much JJ cord-022526-j9kg00qf 4506 10 sand sand NN cord-022526-j9kg00qf 4506 11 as as IN cord-022526-j9kg00qf 4506 12 possible possible JJ cord-022526-j9kg00qf 4506 13 . . . cord-022526-j9kg00qf 4507 1 Prevention prevention NN cord-022526-j9kg00qf 4507 2 of of IN cord-022526-j9kg00qf 4507 3 the the DT cord-022526-j9kg00qf 4507 4 disease disease NN cord-022526-j9kg00qf 4507 5 is be VBZ cord-022526-j9kg00qf 4507 6 important important JJ cord-022526-j9kg00qf 4507 7 , , , cord-022526-j9kg00qf 4507 8 and and CC cord-022526-j9kg00qf 4507 9 recurrence recurrence NN cord-022526-j9kg00qf 4507 10 is be VBZ cord-022526-j9kg00qf 4507 11 not not RB cord-022526-j9kg00qf 4507 12 unusual unusual JJ cord-022526-j9kg00qf 4507 13 . . . cord-022526-j9kg00qf 4508 1 lumen lumen JJ cord-022526-j9kg00qf 4508 2 results result NNS cord-022526-j9kg00qf 4508 3 in in IN cord-022526-j9kg00qf 4508 4 clinical clinical JJ cord-022526-j9kg00qf 4508 5 signs sign NNS cord-022526-j9kg00qf 4508 6 similar similar JJ cord-022526-j9kg00qf 4508 7 to to IN cord-022526-j9kg00qf 4508 8 those those DT cord-022526-j9kg00qf 4508 9 of of IN cord-022526-j9kg00qf 4508 10 simple simple JJ cord-022526-j9kg00qf 4508 11 obstruction obstruction NN cord-022526-j9kg00qf 4508 12 , , , cord-022526-j9kg00qf 4508 13 occlusion occlusion NN cord-022526-j9kg00qf 4508 14 of of IN cord-022526-j9kg00qf 4508 15 the the DT cord-022526-j9kg00qf 4508 16 blood blood NN cord-022526-j9kg00qf 4508 17 supply supply NN cord-022526-j9kg00qf 4508 18 results result NNS cord-022526-j9kg00qf 4508 19 in in IN cord-022526-j9kg00qf 4508 20 a a DT cord-022526-j9kg00qf 4508 21 more more RBR cord-022526-j9kg00qf 4508 22 rapid rapid JJ cord-022526-j9kg00qf 4508 23 deterioration deterioration NN cord-022526-j9kg00qf 4508 24 of of IN cord-022526-j9kg00qf 4508 25 the the DT cord-022526-j9kg00qf 4508 26 intestinal intestinal JJ cord-022526-j9kg00qf 4508 27 mucosa mucosa NN cord-022526-j9kg00qf 4508 28 and and CC cord-022526-j9kg00qf 4508 29 subsequent subsequent JJ cord-022526-j9kg00qf 4508 30 onset onset NN cord-022526-j9kg00qf 4508 31 of of IN cord-022526-j9kg00qf 4508 32 endotoxemic endotoxemic JJ cord-022526-j9kg00qf 4508 33 shock shock NN cord-022526-j9kg00qf 4508 34 . . . cord-022526-j9kg00qf 4509 1 Although although IN cord-022526-j9kg00qf 4509 2 a a DT cord-022526-j9kg00qf 4509 3 great great JJ cord-022526-j9kg00qf 4509 4 deal deal NN cord-022526-j9kg00qf 4509 5 of of IN cord-022526-j9kg00qf 4509 6 interest interest NN cord-022526-j9kg00qf 4509 7 in in IN cord-022526-j9kg00qf 4509 8 the the DT cord-022526-j9kg00qf 4509 9 relevance relevance NN cord-022526-j9kg00qf 4509 10 and and CC cord-022526-j9kg00qf 4509 11 treatment treatment NN cord-022526-j9kg00qf 4509 12 of of IN cord-022526-j9kg00qf 4509 13 intestinal intestinal JJ cord-022526-j9kg00qf 4509 14 reperfusion reperfusion NN cord-022526-j9kg00qf 4509 15 injury injury NN cord-022526-j9kg00qf 4509 16 has have VBZ cord-022526-j9kg00qf 4509 17 arisen arise VBN cord-022526-j9kg00qf 4509 18 recently recently RB cord-022526-j9kg00qf 4509 19 , , , cord-022526-j9kg00qf 4509 20 1 1 CD cord-022526-j9kg00qf 4509 21 - - SYM cord-022526-j9kg00qf 4509 22 3 3 CD cord-022526-j9kg00qf 4509 23 the the DT cord-022526-j9kg00qf 4509 24 lesion lesion NN cord-022526-j9kg00qf 4509 25 that that WDT cord-022526-j9kg00qf 4509 26 develops develop VBZ cord-022526-j9kg00qf 4509 27 during during IN cord-022526-j9kg00qf 4509 28 strangulation strangulation NN cord-022526-j9kg00qf 4509 29 is be VBZ cord-022526-j9kg00qf 4509 30 often often RB cord-022526-j9kg00qf 4509 31 severe severe JJ cord-022526-j9kg00qf 4509 32 , , , cord-022526-j9kg00qf 4509 33 leaving leave VBG cord-022526-j9kg00qf 4509 34 little little JJ cord-022526-j9kg00qf 4509 35 viable viable JJ cord-022526-j9kg00qf 4509 36 bowel bowel NN cord-022526-j9kg00qf 4509 37 for for IN cord-022526-j9kg00qf 4509 38 further further JJ cord-022526-j9kg00qf 4509 39 injury injury NN cord-022526-j9kg00qf 4509 40 during during IN cord-022526-j9kg00qf 4509 41 reperfusion reperfusion NN cord-022526-j9kg00qf 4509 42 . . . cord-022526-j9kg00qf 4510 1 2 2 LS cord-022526-j9kg00qf 4511 1 Although although IN cord-022526-j9kg00qf 4511 2 extensive extensive JJ cord-022526-j9kg00qf 4511 3 lengths length NNS cord-022526-j9kg00qf 4511 4 of of IN cord-022526-j9kg00qf 4511 5 strangulated strangulated JJ cord-022526-j9kg00qf 4511 6 small small JJ cord-022526-j9kg00qf 4511 7 intestine intestine NN cord-022526-j9kg00qf 4511 8 may may MD cord-022526-j9kg00qf 4511 9 be be VB cord-022526-j9kg00qf 4511 10 resected resect VBN cord-022526-j9kg00qf 4511 11 , , , cord-022526-j9kg00qf 4511 12 strangulation strangulation NN cord-022526-j9kg00qf 4511 13 of of IN cord-022526-j9kg00qf 4511 14 the the DT cord-022526-j9kg00qf 4511 15 large large JJ cord-022526-j9kg00qf 4511 16 colon colon NN cord-022526-j9kg00qf 4511 17 presents present VBZ cord-022526-j9kg00qf 4511 18 a a DT cord-022526-j9kg00qf 4511 19 much much RB cord-022526-j9kg00qf 4511 20 greater great JJR cord-022526-j9kg00qf 4511 21 treatment treatment NN cord-022526-j9kg00qf 4511 22 dilemma dilemma NN cord-022526-j9kg00qf 4511 23 because because IN cord-022526-j9kg00qf 4511 24 strangulated strangulated JJ cord-022526-j9kg00qf 4511 25 intestine intestine NN cord-022526-j9kg00qf 4511 26 usually usually RB cord-022526-j9kg00qf 4511 27 extends extend VBZ cord-022526-j9kg00qf 4511 28 beyond beyond IN cord-022526-j9kg00qf 4511 29 the the DT cord-022526-j9kg00qf 4511 30 limits limit NNS cord-022526-j9kg00qf 4511 31 of of IN cord-022526-j9kg00qf 4511 32 surgical surgical JJ cord-022526-j9kg00qf 4511 33 resection resection NN cord-022526-j9kg00qf 4511 34 . . . cord-022526-j9kg00qf 4512 1 4 4 LS cord-022526-j9kg00qf 4513 1 Therefore therefore RB cord-022526-j9kg00qf 4513 2 horses horse NNS cord-022526-j9kg00qf 4513 3 with with IN cord-022526-j9kg00qf 4513 4 large large JJ cord-022526-j9kg00qf 4513 5 intestinal intestinal JJ cord-022526-j9kg00qf 4513 6 strangulation strangulation NN cord-022526-j9kg00qf 4513 7 often often RB cord-022526-j9kg00qf 4513 8 recover recover VBP cord-022526-j9kg00qf 4513 9 with with IN cord-022526-j9kg00qf 4513 10 extensive extensive JJ cord-022526-j9kg00qf 4513 11 intestinal intestinal JJ cord-022526-j9kg00qf 4513 12 injury injury NN cord-022526-j9kg00qf 4513 13 left leave VBN cord-022526-j9kg00qf 4513 14 in in IN cord-022526-j9kg00qf 4513 15 place place NN cord-022526-j9kg00qf 4513 16 . . . cord-022526-j9kg00qf 4514 1 Thus thus RB cord-022526-j9kg00qf 4514 2 subtle subtle JJ cord-022526-j9kg00qf 4514 3 degrees degree NNS cord-022526-j9kg00qf 4514 4 of of IN cord-022526-j9kg00qf 4514 5 reperfusion reperfusion NN cord-022526-j9kg00qf 4514 6 injury injury NN cord-022526-j9kg00qf 4514 7 may may MD cord-022526-j9kg00qf 4514 8 be be VB cord-022526-j9kg00qf 4514 9 important important JJ cord-022526-j9kg00qf 4514 10 in in IN cord-022526-j9kg00qf 4514 11 horses horse NNS cord-022526-j9kg00qf 4514 12 with with IN cord-022526-j9kg00qf 4514 13 large large JJ cord-022526-j9kg00qf 4514 14 colon colon NN cord-022526-j9kg00qf 4514 15 disease disease NN cord-022526-j9kg00qf 4514 16 , , , cord-022526-j9kg00qf 4514 17 warranting warrant VBG cord-022526-j9kg00qf 4514 18 further further JJ cord-022526-j9kg00qf 4514 19 work work NN cord-022526-j9kg00qf 4514 20 in in IN cord-022526-j9kg00qf 4514 21 this this DT cord-022526-j9kg00qf 4514 22 area area NN cord-022526-j9kg00qf 4514 23 in in IN cord-022526-j9kg00qf 4514 24 an an DT cord-022526-j9kg00qf 4514 25 attempt attempt NN cord-022526-j9kg00qf 4514 26 to to TO cord-022526-j9kg00qf 4514 27 reduce reduce VB cord-022526-j9kg00qf 4514 28 mortality mortality NN cord-022526-j9kg00qf 4514 29 . . . cord-022526-j9kg00qf 4515 1 3 3 CD cord-022526-j9kg00qf 4515 2 Strangulating strangulating JJ cord-022526-j9kg00qf 4515 3 obstruction obstruction NN cord-022526-j9kg00qf 4515 4 may may MD cord-022526-j9kg00qf 4515 5 be be VB cord-022526-j9kg00qf 4515 6 divided divide VBN cord-022526-j9kg00qf 4515 7 into into IN cord-022526-j9kg00qf 4515 8 hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4515 9 and and CC cord-022526-j9kg00qf 4515 10 ischemic ischemic JJ cord-022526-j9kg00qf 4515 11 forms form NNS cord-022526-j9kg00qf 4515 12 . . . cord-022526-j9kg00qf 4516 1 5 5 CD cord-022526-j9kg00qf 4516 2 , , , cord-022526-j9kg00qf 4516 3 6 6 CD cord-022526-j9kg00qf 4516 4 Hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 4516 5 strangulating strangulating JJ cord-022526-j9kg00qf 4516 6 obstruction obstruction NN cord-022526-j9kg00qf 4516 7 , , , cord-022526-j9kg00qf 4516 8 which which WDT cord-022526-j9kg00qf 4516 9 is be VBZ cord-022526-j9kg00qf 4516 10 most most RBS cord-022526-j9kg00qf 4516 11 common common JJ cord-022526-j9kg00qf 4516 12 , , , cord-022526-j9kg00qf 4516 13 involves involve VBZ cord-022526-j9kg00qf 4516 14 initial initial JJ cord-022526-j9kg00qf 4516 15 occlusion occlusion NN cord-022526-j9kg00qf 4516 16 of of IN cord-022526-j9kg00qf 4516 17 veins vein NNS cord-022526-j9kg00qf 4516 18 before before IN cord-022526-j9kg00qf 4516 19 occlusion occlusion NN cord-022526-j9kg00qf 4516 20 of of IN cord-022526-j9kg00qf 4516 21 arteries artery NNS cord-022526-j9kg00qf 4516 22 because because IN cord-022526-j9kg00qf 4516 23 of of IN cord-022526-j9kg00qf 4516 24 the the DT cord-022526-j9kg00qf 4516 25 greater great JJR cord-022526-j9kg00qf 4516 26 stiffness stiffness NN cord-022526-j9kg00qf 4516 27 of of IN cord-022526-j9kg00qf 4516 28 arterial arterial JJ cord-022526-j9kg00qf 4516 29 walls wall NNS cord-022526-j9kg00qf 4516 30 . . . cord-022526-j9kg00qf 4517 1 This this DT cord-022526-j9kg00qf 4517 2 lesion lesion NN cord-022526-j9kg00qf 4517 3 is be VBZ cord-022526-j9kg00qf 4517 4 characterized characterize VBN cord-022526-j9kg00qf 4517 5 by by IN cord-022526-j9kg00qf 4517 6 a a DT cord-022526-j9kg00qf 4517 7 darkened darken VBN cord-022526-j9kg00qf 4517 8 appearance appearance NN cord-022526-j9kg00qf 4517 9 to to IN cord-022526-j9kg00qf 4517 10 affected affected JJ cord-022526-j9kg00qf 4517 11 bowel bowel NN cord-022526-j9kg00qf 4517 12 and and CC cord-022526-j9kg00qf 4517 13 increased increased JJ cord-022526-j9kg00qf 4517 14 thickness thickness NN cord-022526-j9kg00qf 4517 15 as as IN cord-022526-j9kg00qf 4517 16 blood blood NN cord-022526-j9kg00qf 4517 17 is be VBZ cord-022526-j9kg00qf 4517 18 pumped pump VBN cord-022526-j9kg00qf 4517 19 into into IN cord-022526-j9kg00qf 4517 20 the the DT cord-022526-j9kg00qf 4517 21 lesion lesion NN cord-022526-j9kg00qf 4517 22 . . . cord-022526-j9kg00qf 4518 1 Ischemic ischemic JJ cord-022526-j9kg00qf 4518 2 strangulating strangulating JJ cord-022526-j9kg00qf 4518 3 obstruction obstruction NN cord-022526-j9kg00qf 4518 4 occurs occur VBZ cord-022526-j9kg00qf 4518 5 if if IN cord-022526-j9kg00qf 4518 6 the the DT cord-022526-j9kg00qf 4518 7 intestine intestine NN cord-022526-j9kg00qf 4518 8 is be VBZ cord-022526-j9kg00qf 4518 9 twisted twist VBN cord-022526-j9kg00qf 4518 10 tightly tightly RB cord-022526-j9kg00qf 4518 11 enough enough RB cord-022526-j9kg00qf 4518 12 to to TO cord-022526-j9kg00qf 4518 13 occlude occlude VB cord-022526-j9kg00qf 4518 14 arteries artery NNS cord-022526-j9kg00qf 4518 15 and and CC cord-022526-j9kg00qf 4518 16 veins vein NNS cord-022526-j9kg00qf 4518 17 simultaneously simultaneously RB cord-022526-j9kg00qf 4518 18 . . . cord-022526-j9kg00qf 4519 1 In in IN cord-022526-j9kg00qf 4519 2 the the DT cord-022526-j9kg00qf 4519 3 case case NN cord-022526-j9kg00qf 4519 4 of of IN cord-022526-j9kg00qf 4519 5 the the DT cord-022526-j9kg00qf 4519 6 colon colon NN cord-022526-j9kg00qf 4519 7 , , , cord-022526-j9kg00qf 4519 8 such such JJ cord-022526-j9kg00qf 4519 9 strangulation strangulation NN cord-022526-j9kg00qf 4519 10 has have VBZ cord-022526-j9kg00qf 4519 11 been be VBN cord-022526-j9kg00qf 4519 12 suggested suggest VBN cord-022526-j9kg00qf 4519 13 to to TO cord-022526-j9kg00qf 4519 14 be be VB cord-022526-j9kg00qf 4519 15 determined determine VBN cord-022526-j9kg00qf 4519 16 by by IN cord-022526-j9kg00qf 4519 17 how how WRB cord-022526-j9kg00qf 4519 18 much much JJ cord-022526-j9kg00qf 4519 19 ingesta ingesta JJ cord-022526-j9kg00qf 4519 20 is be VBZ cord-022526-j9kg00qf 4519 21 in in IN cord-022526-j9kg00qf 4519 22 the the DT cord-022526-j9kg00qf 4519 23 colon colon NN cord-022526-j9kg00qf 4519 24 , , , cord-022526-j9kg00qf 4519 25 because because IN cord-022526-j9kg00qf 4519 26 intestinal intestinal JJ cord-022526-j9kg00qf 4519 27 contents content NNS cord-022526-j9kg00qf 4519 28 may may MD cord-022526-j9kg00qf 4519 29 prevent prevent VB cord-022526-j9kg00qf 4519 30 the the DT cord-022526-j9kg00qf 4519 31 intestine intestine NN cord-022526-j9kg00qf 4519 32 from from IN cord-022526-j9kg00qf 4519 33 twisting twist VBG cord-022526-j9kg00qf 4519 34 tightly tightly RB cord-022526-j9kg00qf 4519 35 . . . cord-022526-j9kg00qf 4520 1 7 7 CD cord-022526-j9kg00qf 4520 2 Tissue tissue NN cord-022526-j9kg00qf 4520 3 involved involve VBN cord-022526-j9kg00qf 4520 4 in in IN cord-022526-j9kg00qf 4520 5 ischemic ischemic JJ cord-022526-j9kg00qf 4520 6 strangulating strangulating JJ cord-022526-j9kg00qf 4520 7 obstruction obstruction NN cord-022526-j9kg00qf 4520 8 appears appear VBZ cord-022526-j9kg00qf 4520 9 pale pale JJ cord-022526-j9kg00qf 4520 10 and and CC cord-022526-j9kg00qf 4520 11 of of IN cord-022526-j9kg00qf 4520 12 normal normal JJ cord-022526-j9kg00qf 4520 13 or or CC cord-022526-j9kg00qf 4520 14 reduced reduced JJ cord-022526-j9kg00qf 4520 15 thickness thickness NN cord-022526-j9kg00qf 4520 16 because because IN cord-022526-j9kg00qf 4520 17 of of IN cord-022526-j9kg00qf 4520 18 a a DT cord-022526-j9kg00qf 4520 19 complete complete JJ cord-022526-j9kg00qf 4520 20 lack lack NN cord-022526-j9kg00qf 4520 21 of of IN cord-022526-j9kg00qf 4520 22 blood blood NN cord-022526-j9kg00qf 4520 23 flow flow NN cord-022526-j9kg00qf 4521 1 ( ( -LRB- cord-022526-j9kg00qf 4521 2 Figure figure NN cord-022526-j9kg00qf 4521 3 13 13 CD cord-022526-j9kg00qf 4521 4 .14 .14 CD cord-022526-j9kg00qf 4521 5 - - SYM cord-022526-j9kg00qf 4521 6 1 1 CD cord-022526-j9kg00qf 4521 7 ) ) -RRB- cord-022526-j9kg00qf 4521 8 . . . cord-022526-j9kg00qf 4522 1 Bowel bowel NN cord-022526-j9kg00qf 4522 2 peripheral peripheral JJ cord-022526-j9kg00qf 4522 3 to to IN cord-022526-j9kg00qf 4522 4 strangulating strangulating JJ cord-022526-j9kg00qf 4522 5 lesions lesion NNS cord-022526-j9kg00qf 4522 6 also also RB cord-022526-j9kg00qf 4522 7 may may MD cord-022526-j9kg00qf 4522 8 become become VB cord-022526-j9kg00qf 4522 9 injured injure VBN cord-022526-j9kg00qf 4522 10 because because IN cord-022526-j9kg00qf 4522 11 of of IN cord-022526-j9kg00qf 4522 12 distention distention NN cord-022526-j9kg00qf 4522 13 , , , cord-022526-j9kg00qf 4522 14 which which WDT cord-022526-j9kg00qf 4522 15 reduces reduce VBZ cord-022526-j9kg00qf 4522 16 mural mural NN cord-022526-j9kg00qf 4522 17 blood blood NN cord-022526-j9kg00qf 4522 18 flow flow NN cord-022526-j9kg00qf 4522 19 once once IN cord-022526-j9kg00qf 4522 20 it -PRON- PRP cord-022526-j9kg00qf 4522 21 reaches reach VBZ cord-022526-j9kg00qf 4522 22 critical critical JJ cord-022526-j9kg00qf 4522 23 levels level NNS cord-022526-j9kg00qf 4522 24 . . . cord-022526-j9kg00qf 4523 1 Furthermore furthermore RB cord-022526-j9kg00qf 4523 2 , , , cord-022526-j9kg00qf 4523 3 as as IN cord-022526-j9kg00qf 4523 4 this this DT cord-022526-j9kg00qf 4523 5 intestine intestine NN cord-022526-j9kg00qf 4523 6 is be VBZ cord-022526-j9kg00qf 4523 7 decompressed decompress VBN cord-022526-j9kg00qf 4523 8 , , , cord-022526-j9kg00qf 4523 9 it -PRON- PRP cord-022526-j9kg00qf 4523 10 also also RB cord-022526-j9kg00qf 4523 11 may may MD cord-022526-j9kg00qf 4523 12 undergo undergo VB cord-022526-j9kg00qf 4523 13 reperfusion reperfusion NN cord-022526-j9kg00qf 4523 14 injury injury NN cord-022526-j9kg00qf 4523 15 . . . cord-022526-j9kg00qf 4524 1 [ [ -LRB- cord-022526-j9kg00qf 4524 2 8 8 CD cord-022526-j9kg00qf 4524 3 ] ] -RRB- cord-022526-j9kg00qf 4524 4 [ [ -LRB- cord-022526-j9kg00qf 4524 5 9 9 CD cord-022526-j9kg00qf 4524 6 ] ] -RRB- cord-022526-j9kg00qf 4524 7 [ [ -LRB- cord-022526-j9kg00qf 4524 8 10 10 CD cord-022526-j9kg00qf 4524 9 ] ] -RRB- cord-022526-j9kg00qf 4524 10 Small small JJ cord-022526-j9kg00qf 4524 11 Intestinal intestinal JJ cord-022526-j9kg00qf 4524 12 Strangulation strangulation NN cord-022526-j9kg00qf 4524 13 Horses horse NNS cord-022526-j9kg00qf 4524 14 with with IN cord-022526-j9kg00qf 4524 15 small small JJ cord-022526-j9kg00qf 4524 16 intestinal intestinal JJ cord-022526-j9kg00qf 4524 17 strangulating strangulating JJ cord-022526-j9kg00qf 4524 18 obstruction obstruction NN cord-022526-j9kg00qf 4524 19 typically typically RB cord-022526-j9kg00qf 4524 20 have have VBP cord-022526-j9kg00qf 4524 21 moderate moderate JJ cord-022526-j9kg00qf 4524 22 to to IN cord-022526-j9kg00qf 4524 23 severe severe JJ cord-022526-j9kg00qf 4524 24 signs sign NNS cord-022526-j9kg00qf 4524 25 of of IN cord-022526-j9kg00qf 4524 26 abdominal abdominal JJ cord-022526-j9kg00qf 4524 27 pain pain NN cord-022526-j9kg00qf 4524 28 that that WDT cord-022526-j9kg00qf 4524 29 are be VBP cord-022526-j9kg00qf 4524 30 only only RB cord-022526-j9kg00qf 4524 31 intermittently intermittently RB cord-022526-j9kg00qf 4524 32 responsive responsive JJ cord-022526-j9kg00qf 4524 33 to to IN cord-022526-j9kg00qf 4524 34 analgesic analgesic JJ cord-022526-j9kg00qf 4524 35 medications medication NNS cord-022526-j9kg00qf 4524 36 . . . cord-022526-j9kg00qf 4525 1 During during IN cord-022526-j9kg00qf 4525 2 the the DT cord-022526-j9kg00qf 4525 3 latter latter JJ cord-022526-j9kg00qf 4525 4 stages stage NNS cord-022526-j9kg00qf 4525 5 of of IN cord-022526-j9kg00qf 4525 6 the the DT cord-022526-j9kg00qf 4525 7 disease disease NN cord-022526-j9kg00qf 4525 8 process process NN cord-022526-j9kg00qf 4525 9 , , , cord-022526-j9kg00qf 4525 10 horses horse NNS cord-022526-j9kg00qf 4525 11 may may MD cord-022526-j9kg00qf 4525 12 become become VB cord-022526-j9kg00qf 4525 13 profoundly profoundly RB cord-022526-j9kg00qf 4525 14 depressed depressed JJ cord-022526-j9kg00qf 4525 15 rather rather RB cord-022526-j9kg00qf 4525 16 than than IN cord-022526-j9kg00qf 4525 17 painful painful JJ cord-022526-j9kg00qf 4525 18 as as IN cord-022526-j9kg00qf 4525 19 affected affect VBN cord-022526-j9kg00qf 4525 20 intestine intestine NN cord-022526-j9kg00qf 4525 21 necroses necrose NNS cord-022526-j9kg00qf 4525 22 . . . cord-022526-j9kg00qf 4526 1 Horses horse NNS cord-022526-j9kg00qf 4526 2 have have VBP cord-022526-j9kg00qf 4526 3 progressive progressive JJ cord-022526-j9kg00qf 4526 4 signs sign NNS cord-022526-j9kg00qf 4526 5 of of IN cord-022526-j9kg00qf 4526 6 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4526 7 , , , cord-022526-j9kg00qf 4526 8 including include VBG cord-022526-j9kg00qf 4526 9 congested congested JJ cord-022526-j9kg00qf 4526 10 mucous mucous JJ cord-022526-j9kg00qf 4526 11 membranes membrane NNS cord-022526-j9kg00qf 4526 12 , , , cord-022526-j9kg00qf 4526 13 delayed delay VBN cord-022526-j9kg00qf 4526 14 capillary capillary JJ cord-022526-j9kg00qf 4526 15 refill refill NN cord-022526-j9kg00qf 4526 16 time time NN cord-022526-j9kg00qf 4526 17 , , , cord-022526-j9kg00qf 4526 18 and and CC cord-022526-j9kg00qf 4526 19 an an DT cord-022526-j9kg00qf 4526 20 elevated elevated JJ cord-022526-j9kg00qf 4526 21 heart heart NN cord-022526-j9kg00qf 4526 22 rate rate NN cord-022526-j9kg00qf 4526 23 ( ( -LRB- cord-022526-j9kg00qf 4526 24 > > SYM cord-022526-j9kg00qf 4526 25 60 60 CD cord-022526-j9kg00qf 4526 26 beats beat NNS cord-022526-j9kg00qf 4526 27 / / SYM cord-022526-j9kg00qf 4526 28 min min NN cord-022526-j9kg00qf 4526 29 in in IN cord-022526-j9kg00qf 4526 30 most most JJS cord-022526-j9kg00qf 4526 31 cases case NNS cord-022526-j9kg00qf 4526 32 ) ) -RRB- cord-022526-j9kg00qf 4526 33 . . . cord-022526-j9kg00qf 4527 1 In in IN cord-022526-j9kg00qf 4527 2 addition addition NN cord-022526-j9kg00qf 4527 3 , , , cord-022526-j9kg00qf 4527 4 one one CD cord-022526-j9kg00qf 4527 5 typically typically RB cord-022526-j9kg00qf 4527 6 obtains obtain VBZ cord-022526-j9kg00qf 4527 7 reflux reflux NN cord-022526-j9kg00qf 4527 8 following follow VBG cord-022526-j9kg00qf 4527 9 passage passage NN cord-022526-j9kg00qf 4527 10 of of IN cord-022526-j9kg00qf 4527 11 a a DT cord-022526-j9kg00qf 4527 12 stomach stomach NN cord-022526-j9kg00qf 4527 13 tube tube NN cord-022526-j9kg00qf 4527 14 , , , cord-022526-j9kg00qf 4527 15 and and CC cord-022526-j9kg00qf 4527 16 one one CD cord-022526-j9kg00qf 4527 17 usually usually RB cord-022526-j9kg00qf 4527 18 can can MD cord-022526-j9kg00qf 4527 19 detect detect VB cord-022526-j9kg00qf 4527 20 loops loop NNS cord-022526-j9kg00qf 4527 21 of of IN cord-022526-j9kg00qf 4527 22 distended distended JJ cord-022526-j9kg00qf 4527 23 small small JJ cord-022526-j9kg00qf 4527 24 intestine intestine NN cord-022526-j9kg00qf 4527 25 on on IN cord-022526-j9kg00qf 4527 26 rectal rectal JJ cord-022526-j9kg00qf 4527 27 palpation palpation NN cord-022526-j9kg00qf 4527 28 of of IN cord-022526-j9kg00qf 4527 29 the the DT cord-022526-j9kg00qf 4527 30 abdomen abdomen NN cord-022526-j9kg00qf 4527 31 . . . cord-022526-j9kg00qf 4528 1 11 11 CD cord-022526-j9kg00qf 4529 1 However however RB cord-022526-j9kg00qf 4529 2 , , , cord-022526-j9kg00qf 4529 3 these these DT cord-022526-j9kg00qf 4529 4 latter latter JJ cord-022526-j9kg00qf 4529 5 findings finding NNS cord-022526-j9kg00qf 4529 6 vary vary VBP cord-022526-j9kg00qf 4529 7 depending depend VBG cord-022526-j9kg00qf 4529 8 on on IN cord-022526-j9kg00qf 4529 9 the the DT cord-022526-j9kg00qf 4529 10 duration duration NN cord-022526-j9kg00qf 4529 11 and and CC cord-022526-j9kg00qf 4529 12 location location NN cord-022526-j9kg00qf 4529 13 of of IN cord-022526-j9kg00qf 4529 14 the the DT cord-022526-j9kg00qf 4529 15 obstruction obstruction NN cord-022526-j9kg00qf 4529 16 . . . cord-022526-j9kg00qf 4530 1 For for IN cord-022526-j9kg00qf 4530 2 example example NN cord-022526-j9kg00qf 4530 3 , , , cord-022526-j9kg00qf 4530 4 horses horse NNS cord-022526-j9kg00qf 4530 5 with with IN cord-022526-j9kg00qf 4530 6 ileal ileal JJ cord-022526-j9kg00qf 4530 7 obstructions obstruction NNS cord-022526-j9kg00qf 4530 8 tend tend VBP cord-022526-j9kg00qf 4530 9 to to TO cord-022526-j9kg00qf 4530 10 reflux reflux VB cord-022526-j9kg00qf 4530 11 later later RB cord-022526-j9kg00qf 4530 12 in in IN cord-022526-j9kg00qf 4530 13 the the DT cord-022526-j9kg00qf 4530 14 course course NN cord-022526-j9kg00qf 4530 15 of of IN cord-022526-j9kg00qf 4530 16 the the DT cord-022526-j9kg00qf 4530 17 disease disease NN cord-022526-j9kg00qf 4530 18 process process NN cord-022526-j9kg00qf 4530 19 than than IN cord-022526-j9kg00qf 4530 20 horses horse NNS cord-022526-j9kg00qf 4530 21 with with IN cord-022526-j9kg00qf 4530 22 a a DT cord-022526-j9kg00qf 4530 23 jejunal jejunal JJ cord-022526-j9kg00qf 4530 24 obstruction obstruction NN cord-022526-j9kg00qf 4530 25 . . . cord-022526-j9kg00qf 4531 1 Furthermore furthermore RB cord-022526-j9kg00qf 4531 2 , , , cord-022526-j9kg00qf 4531 3 a a DT cord-022526-j9kg00qf 4531 4 horse horse NN cord-022526-j9kg00qf 4531 5 that that WDT cord-022526-j9kg00qf 4531 6 has have VBZ cord-022526-j9kg00qf 4531 7 an an DT cord-022526-j9kg00qf 4531 8 entrapment entrapment NN cord-022526-j9kg00qf 4531 9 of of IN cord-022526-j9kg00qf 4531 10 small small JJ cord-022526-j9kg00qf 4531 11 intestine intestine NN cord-022526-j9kg00qf 4531 12 in in IN cord-022526-j9kg00qf 4531 13 the the DT cord-022526-j9kg00qf 4531 14 epiploic epiploic JJ cord-022526-j9kg00qf 4531 15 foramen foramen NN cord-022526-j9kg00qf 4531 16 may may MD cord-022526-j9kg00qf 4531 17 not not RB cord-022526-j9kg00qf 4531 18 have have VB cord-022526-j9kg00qf 4531 19 palpable palpable JJ cord-022526-j9kg00qf 4531 20 loops loop NNS cord-022526-j9kg00qf 4531 21 of of IN cord-022526-j9kg00qf 4531 22 small small JJ cord-022526-j9kg00qf 4531 23 intestine intestine NN cord-022526-j9kg00qf 4531 24 because because IN cord-022526-j9kg00qf 4531 25 of of IN cord-022526-j9kg00qf 4531 26 the the DT cord-022526-j9kg00qf 4531 27 cranial cranial JJ cord-022526-j9kg00qf 4531 28 location location NN cord-022526-j9kg00qf 4531 29 of of IN cord-022526-j9kg00qf 4531 30 these these DT cord-022526-j9kg00qf 4531 31 structures structure NNS cord-022526-j9kg00qf 4531 32 . . . cord-022526-j9kg00qf 4532 1 12 12 CD cord-022526-j9kg00qf 4533 1 Abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4533 2 can can MD cord-022526-j9kg00qf 4533 3 provide provide VB cord-022526-j9kg00qf 4533 4 critical critical JJ cord-022526-j9kg00qf 4533 5 information information NN cord-022526-j9kg00qf 4533 6 on on IN cord-022526-j9kg00qf 4533 7 the the DT cord-022526-j9kg00qf 4533 8 integrity integrity NN cord-022526-j9kg00qf 4533 9 of of IN cord-022526-j9kg00qf 4533 10 the the DT cord-022526-j9kg00qf 4533 11 intestine intestine NN cord-022526-j9kg00qf 4533 12 and and CC cord-022526-j9kg00qf 4533 13 is be VBZ cord-022526-j9kg00qf 4533 14 indicated indicate VBN cord-022526-j9kg00qf 4533 15 in in IN cord-022526-j9kg00qf 4533 16 horses horse NNS cord-022526-j9kg00qf 4533 17 in in IN cord-022526-j9kg00qf 4533 18 which which WDT cord-022526-j9kg00qf 4533 19 one one CD cord-022526-j9kg00qf 4533 20 suspects suspect VBZ cord-022526-j9kg00qf 4533 21 strangulation strangulation NN cord-022526-j9kg00qf 4533 22 of of IN cord-022526-j9kg00qf 4533 23 the the DT cord-022526-j9kg00qf 4533 24 small small JJ cord-022526-j9kg00qf 4533 25 intestine intestine NN cord-022526-j9kg00qf 4533 26 . . . cord-022526-j9kg00qf 4534 1 13 13 CD cord-022526-j9kg00qf 4535 1 A a DT cord-022526-j9kg00qf 4535 2 horse horse NN cord-022526-j9kg00qf 4535 3 that that WDT cord-022526-j9kg00qf 4535 4 has have VBZ cord-022526-j9kg00qf 4535 5 signs sign NNS cord-022526-j9kg00qf 4535 6 compatible compatible JJ cord-022526-j9kg00qf 4535 7 with with IN cord-022526-j9kg00qf 4535 8 a a DT cord-022526-j9kg00qf 4535 9 small small JJ cord-022526-j9kg00qf 4535 10 intestinal intestinal JJ cord-022526-j9kg00qf 4535 11 obstruction obstruction NN cord-022526-j9kg00qf 4535 12 and and CC cord-022526-j9kg00qf 4535 13 additionally additionally RB cord-022526-j9kg00qf 4535 14 has have VBZ cord-022526-j9kg00qf 4535 15 serosanguinous serosanguinous JJ cord-022526-j9kg00qf 4535 16 abdominal abdominal JJ cord-022526-j9kg00qf 4535 17 fluid fluid NN cord-022526-j9kg00qf 4535 18 with with IN cord-022526-j9kg00qf 4535 19 an an DT cord-022526-j9kg00qf 4535 20 elevated elevated JJ cord-022526-j9kg00qf 4535 21 protein protein NN cord-022526-j9kg00qf 4535 22 level level NN cord-022526-j9kg00qf 4535 23 ( ( -LRB- cord-022526-j9kg00qf 4535 24 > > NFP cord-022526-j9kg00qf 4535 25 2.5 2.5 CD cord-022526-j9kg00qf 4535 26 mg mg NNP cord-022526-j9kg00qf 4535 27 / / SYM cord-022526-j9kg00qf 4535 28 dl dl NNP cord-022526-j9kg00qf 4535 29 ) ) -RRB- cord-022526-j9kg00qf 4535 30 is be VBZ cord-022526-j9kg00qf 4535 31 likely likely JJ cord-022526-j9kg00qf 4535 32 to to TO cord-022526-j9kg00qf 4535 33 require require VB cord-022526-j9kg00qf 4535 34 surgery surgery NN cord-022526-j9kg00qf 4535 35 , , , cord-022526-j9kg00qf 4535 36 although although IN cord-022526-j9kg00qf 4535 37 one one PRP cord-022526-j9kg00qf 4535 38 must must MD cord-022526-j9kg00qf 4535 39 differentiate differentiate VB cord-022526-j9kg00qf 4535 40 these these DT cord-022526-j9kg00qf 4535 41 A A NNP cord-022526-j9kg00qf 4535 42 B B NNP cord-022526-j9kg00qf 4535 43 Figure figure NN cord-022526-j9kg00qf 4535 44 13 13 CD cord-022526-j9kg00qf 4535 45 .14 .14 . cord-022526-j9kg00qf 4536 1 -1 -1 CC cord-022526-j9kg00qf 4536 2 Ischemic ischemic JJ cord-022526-j9kg00qf 4536 3 strangulating strangulating JJ cord-022526-j9kg00qf 4536 4 obstruction obstruction NN cord-022526-j9kg00qf 4536 5 of of IN cord-022526-j9kg00qf 4536 6 the the DT cord-022526-j9kg00qf 4536 7 small small JJ cord-022526-j9kg00qf 4536 8 colon colon NN cord-022526-j9kg00qf 4536 9 by by IN cord-022526-j9kg00qf 4536 10 a a DT cord-022526-j9kg00qf 4536 11 mesenteric mesenteric JJ cord-022526-j9kg00qf 4536 12 lipoma lipoma NN cord-022526-j9kg00qf 4536 13 . . . cord-022526-j9kg00qf 4537 1 A a DT cord-022526-j9kg00qf 4537 2 , , , cord-022526-j9kg00qf 4537 3 The the DT cord-022526-j9kg00qf 4537 4 lipoma lipoma NN cord-022526-j9kg00qf 4537 5 ( ( -LRB- cord-022526-j9kg00qf 4537 6 arrow arrow NN cord-022526-j9kg00qf 4537 7 ) ) -RRB- cord-022526-j9kg00qf 4537 8 has have VBZ cord-022526-j9kg00qf 4537 9 encircled encircle VBN cord-022526-j9kg00qf 4537 10 a a DT cord-022526-j9kg00qf 4537 11 segment segment NN cord-022526-j9kg00qf 4537 12 of of IN cord-022526-j9kg00qf 4537 13 small small JJ cord-022526-j9kg00qf 4537 14 colon colon NN cord-022526-j9kg00qf 4537 15 tightly tightly RB cord-022526-j9kg00qf 4537 16 . . . cord-022526-j9kg00qf 4538 1 B b NN cord-022526-j9kg00qf 4538 2 , , , cord-022526-j9kg00qf 4538 3 Following follow VBG cord-022526-j9kg00qf 4538 4 resection resection NN cord-022526-j9kg00qf 4538 5 of of IN cord-022526-j9kg00qf 4538 6 the the DT cord-022526-j9kg00qf 4538 7 lipoma lipoma NN cord-022526-j9kg00qf 4538 8 , , , cord-022526-j9kg00qf 4538 9 a a DT cord-022526-j9kg00qf 4538 10 pale pale JJ cord-022526-j9kg00qf 4538 11 area area NN cord-022526-j9kg00qf 4538 12 of of IN cord-022526-j9kg00qf 4538 13 strangulated strangulated JJ cord-022526-j9kg00qf 4538 14 small small JJ cord-022526-j9kg00qf 4538 15 colon colon NN cord-022526-j9kg00qf 4538 16 clearly clearly RB cord-022526-j9kg00qf 4538 17 is be VBZ cord-022526-j9kg00qf 4538 18 demarcated demarcate VBN cord-022526-j9kg00qf 4538 19 ( ( -LRB- cord-022526-j9kg00qf 4538 20 arrows arrow NNS cord-022526-j9kg00qf 4538 21 ) ) -RRB- cord-022526-j9kg00qf 4538 22 , , , cord-022526-j9kg00qf 4538 23 the the DT cord-022526-j9kg00qf 4538 24 appearance appearance NN cord-022526-j9kg00qf 4538 25 of of IN cord-022526-j9kg00qf 4538 26 which which WDT cord-022526-j9kg00qf 4538 27 is be VBZ cord-022526-j9kg00qf 4538 28 consistent consistent JJ cord-022526-j9kg00qf 4538 29 with with IN cord-022526-j9kg00qf 4538 30 ischemic ischemic JJ cord-022526-j9kg00qf 4538 31 strangulating strangulating JJ cord-022526-j9kg00qf 4538 32 obstruction obstruction NN cord-022526-j9kg00qf 4538 33 . . . cord-022526-j9kg00qf 4539 1 cases case NNS cord-022526-j9kg00qf 4539 2 from from IN cord-022526-j9kg00qf 4539 3 proximal proximal JJ cord-022526-j9kg00qf 4539 4 enteritis enteritis NN cord-022526-j9kg00qf 4539 5 . . . cord-022526-j9kg00qf 4540 1 In in IN cord-022526-j9kg00qf 4540 2 general general JJ cord-022526-j9kg00qf 4540 3 , , , cord-022526-j9kg00qf 4540 4 horses horse NNS cord-022526-j9kg00qf 4540 5 with with IN cord-022526-j9kg00qf 4540 6 small small JJ cord-022526-j9kg00qf 4540 7 intestinal intestinal JJ cord-022526-j9kg00qf 4540 8 strangulation strangulation NN cord-022526-j9kg00qf 4540 9 show show NN cord-022526-j9kg00qf 4540 10 continued continue VBD cord-022526-j9kg00qf 4540 11 signs sign NNS cord-022526-j9kg00qf 4540 12 of of IN cord-022526-j9kg00qf 4540 13 abdominal abdominal JJ cord-022526-j9kg00qf 4540 14 pain pain NN cord-022526-j9kg00qf 4540 15 , , , cord-022526-j9kg00qf 4540 16 whereas whereas IN cord-022526-j9kg00qf 4540 17 horses horse NNS cord-022526-j9kg00qf 4540 18 with with IN cord-022526-j9kg00qf 4540 19 proximal proximal JJ cord-022526-j9kg00qf 4540 20 enteritis enteritis NN cord-022526-j9kg00qf 4540 21 tend tend VBP cord-022526-j9kg00qf 4540 22 to to TO cord-022526-j9kg00qf 4540 23 be be VB cord-022526-j9kg00qf 4540 24 depressed depress VBN cord-022526-j9kg00qf 4540 25 after after IN cord-022526-j9kg00qf 4540 26 initial initial JJ cord-022526-j9kg00qf 4540 27 episodes episode NNS cord-022526-j9kg00qf 4540 28 of of IN cord-022526-j9kg00qf 4540 29 mild mild JJ cord-022526-j9kg00qf 4540 30 abdominal abdominal JJ cord-022526-j9kg00qf 4540 31 pain pain NN cord-022526-j9kg00qf 4540 32 . . . cord-022526-j9kg00qf 4541 1 In in IN cord-022526-j9kg00qf 4541 2 addition addition NN cord-022526-j9kg00qf 4541 3 , , , cord-022526-j9kg00qf 4541 4 horses horse NNS cord-022526-j9kg00qf 4541 5 with with IN cord-022526-j9kg00qf 4541 6 small small JJ cord-022526-j9kg00qf 4541 7 intestinal intestinal JJ cord-022526-j9kg00qf 4541 8 strangulation strangulation NN cord-022526-j9kg00qf 4541 9 continue continue VBP cord-022526-j9kg00qf 4541 10 to to TO cord-022526-j9kg00qf 4541 11 deteriorate deteriorate VB cord-022526-j9kg00qf 4541 12 clinically clinically RB cord-022526-j9kg00qf 4541 13 despite despite IN cord-022526-j9kg00qf 4541 14 appropriate appropriate JJ cord-022526-j9kg00qf 4541 15 medical medical JJ cord-022526-j9kg00qf 4541 16 therapy therapy NN cord-022526-j9kg00qf 4541 17 and and CC cord-022526-j9kg00qf 4541 18 will will MD cord-022526-j9kg00qf 4541 19 likely likely RB cord-022526-j9kg00qf 4541 20 begin begin VB cord-022526-j9kg00qf 4541 21 to to TO cord-022526-j9kg00qf 4541 22 show show VB cord-022526-j9kg00qf 4541 23 an an DT cord-022526-j9kg00qf 4541 24 increased increase VBN cord-022526-j9kg00qf 4541 25 white white JJ cord-022526-j9kg00qf 4541 26 blood blood NN cord-022526-j9kg00qf 4541 27 cell cell NN cord-022526-j9kg00qf 4541 28 count count NN cord-022526-j9kg00qf 4541 29 ( ( -LRB- cord-022526-j9kg00qf 4541 30 > > VBZ cord-022526-j9kg00qf 4541 31 10,000 10,000 CD cord-022526-j9kg00qf 4541 32 cells/µl cells/µl NNP cord-022526-j9kg00qf 4541 33 ) ) -RRB- cord-022526-j9kg00qf 4541 34 in in IN cord-022526-j9kg00qf 4541 35 the the DT cord-022526-j9kg00qf 4541 36 abdominal abdominal JJ cord-022526-j9kg00qf 4541 37 fluid fluid NN cord-022526-j9kg00qf 4541 38 as as IN cord-022526-j9kg00qf 4541 39 the the DT cord-022526-j9kg00qf 4541 40 duration duration NN cord-022526-j9kg00qf 4541 41 of of IN cord-022526-j9kg00qf 4541 42 strangulation strangulation NN cord-022526-j9kg00qf 4541 43 increases increase NNS cord-022526-j9kg00qf 4541 44 . . . cord-022526-j9kg00qf 4542 1 However however RB cord-022526-j9kg00qf 4542 2 , , , cord-022526-j9kg00qf 4542 3 cases case NNS cord-022526-j9kg00qf 4542 4 occur occur VBP cord-022526-j9kg00qf 4542 5 in in IN cord-022526-j9kg00qf 4542 6 which which WDT cord-022526-j9kg00qf 4542 7 the the DT cord-022526-j9kg00qf 4542 8 differentiation differentiation NN cord-022526-j9kg00qf 4542 9 between between IN cord-022526-j9kg00qf 4542 10 small small JJ cord-022526-j9kg00qf 4542 11 intestinal intestinal JJ cord-022526-j9kg00qf 4542 12 strangulation strangulation NN cord-022526-j9kg00qf 4542 13 and and CC cord-022526-j9kg00qf 4542 14 proximal proximal JJ cord-022526-j9kg00qf 4542 15 enteritis enteritis NN cord-022526-j9kg00qf 4542 16 is be VBZ cord-022526-j9kg00qf 4542 17 not not RB cord-022526-j9kg00qf 4542 18 clear clear JJ cord-022526-j9kg00qf 4542 19 , , , cord-022526-j9kg00qf 4542 20 at at IN cord-022526-j9kg00qf 4542 21 which which WDT cord-022526-j9kg00qf 4542 22 point point NN cord-022526-j9kg00qf 4542 23 one one PRP cord-022526-j9kg00qf 4542 24 may may MD cord-022526-j9kg00qf 4542 25 elect elect VB cord-022526-j9kg00qf 4542 26 surgery surgery NN cord-022526-j9kg00qf 4542 27 rather rather RB cord-022526-j9kg00qf 4542 28 than than IN cord-022526-j9kg00qf 4542 29 risking risk VBG cord-022526-j9kg00qf 4542 30 delay delay NN cord-022526-j9kg00qf 4542 31 of of IN cord-022526-j9kg00qf 4542 32 abdominal abdominal JJ cord-022526-j9kg00qf 4542 33 exploration exploration NN cord-022526-j9kg00qf 4542 34 of of IN cord-022526-j9kg00qf 4542 35 a a DT cord-022526-j9kg00qf 4542 36 horse horse NN cord-022526-j9kg00qf 4542 37 with with IN cord-022526-j9kg00qf 4542 38 a a DT cord-022526-j9kg00qf 4542 39 potential potential JJ cord-022526-j9kg00qf 4542 40 strangulating strangulate VBG cord-022526-j9kg00qf 4542 41 lesion lesion NN cord-022526-j9kg00qf 4542 42 . . . cord-022526-j9kg00qf 4543 1 14 14 CD cord-022526-j9kg00qf 4544 1 The the DT cord-022526-j9kg00qf 4544 2 prognosis prognosis NN cord-022526-j9kg00qf 4544 3 for for IN cord-022526-j9kg00qf 4544 4 survival survival NN cord-022526-j9kg00qf 4544 5 in in IN cord-022526-j9kg00qf 4544 6 horses horse NNS cord-022526-j9kg00qf 4544 7 with with IN cord-022526-j9kg00qf 4544 8 small small JJ cord-022526-j9kg00qf 4544 9 intestinal intestinal JJ cord-022526-j9kg00qf 4544 10 strangulating strangulating JJ cord-022526-j9kg00qf 4544 11 lesions lesion NNS cord-022526-j9kg00qf 4544 12 is be VBZ cord-022526-j9kg00qf 4544 13 generally generally RB cord-022526-j9kg00qf 4544 14 lower low JJR cord-022526-j9kg00qf 4544 15 than than IN cord-022526-j9kg00qf 4544 16 for for IN cord-022526-j9kg00qf 4544 17 most most JJS cord-022526-j9kg00qf 4544 18 forms form NNS cord-022526-j9kg00qf 4544 19 of of IN cord-022526-j9kg00qf 4544 20 colic colic NN cord-022526-j9kg00qf 4544 21 . . . cord-022526-j9kg00qf 4545 1 15 15 CD cord-022526-j9kg00qf 4546 1 However however RB cord-022526-j9kg00qf 4546 2 , , , cord-022526-j9kg00qf 4546 3 recent recent JJ cord-022526-j9kg00qf 4546 4 studies study NNS cord-022526-j9kg00qf 4546 5 indicate indicate VBP cord-022526-j9kg00qf 4546 6 that that IN cord-022526-j9kg00qf 4546 7 in in IN cord-022526-j9kg00qf 4546 8 excess excess NN cord-022526-j9kg00qf 4546 9 of of IN cord-022526-j9kg00qf 4546 10 80 80 CD cord-022526-j9kg00qf 4546 11 % % NN cord-022526-j9kg00qf 4546 12 of of IN cord-022526-j9kg00qf 4546 13 horses horse NNS cord-022526-j9kg00qf 4546 14 with with IN cord-022526-j9kg00qf 4546 15 small small JJ cord-022526-j9kg00qf 4546 16 intestinal intestinal JJ cord-022526-j9kg00qf 4546 17 strangulating strangulating JJ cord-022526-j9kg00qf 4546 18 lesions lesion NNS cord-022526-j9kg00qf 4546 19 are be VBP cord-022526-j9kg00qf 4546 20 discharged discharge VBN cord-022526-j9kg00qf 4546 21 from from IN cord-022526-j9kg00qf 4546 22 the the DT cord-022526-j9kg00qf 4546 23 hospital hospital NN cord-022526-j9kg00qf 4546 24 . . . cord-022526-j9kg00qf 4547 1 16 16 CD cord-022526-j9kg00qf 4548 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 4548 2 , , , cord-022526-j9kg00qf 4548 3 veterinarians veterinarian NNS cord-022526-j9kg00qf 4548 4 should should MD cord-022526-j9kg00qf 4548 5 warn warn VB cord-022526-j9kg00qf 4548 6 owners owner NNS cord-022526-j9kg00qf 4548 7 that that IN cord-022526-j9kg00qf 4548 8 the the DT cord-022526-j9kg00qf 4548 9 long long JJ cord-022526-j9kg00qf 4548 10 - - HYPH cord-022526-j9kg00qf 4548 11 term term NN cord-022526-j9kg00qf 4548 12 survival survival NN cord-022526-j9kg00qf 4548 13 rates rate NNS cord-022526-j9kg00qf 4548 14 are be VBP cord-022526-j9kg00qf 4548 15 reduced reduce VBN cord-022526-j9kg00qf 4548 16 substantially substantially RB cord-022526-j9kg00qf 4548 17 to to IN cord-022526-j9kg00qf 4548 18 below below IN cord-022526-j9kg00qf 4548 19 70 70 CD cord-022526-j9kg00qf 4548 20 % % NN cord-022526-j9kg00qf 4548 21 , , , cord-022526-j9kg00qf 4548 22 17 17 CD cord-022526-j9kg00qf 4548 23 in in IN cord-022526-j9kg00qf 4548 24 part part NN cord-022526-j9kg00qf 4548 25 because because IN cord-022526-j9kg00qf 4548 26 of of IN cord-022526-j9kg00qf 4548 27 long long JJ cord-022526-j9kg00qf 4548 28 - - HYPH cord-022526-j9kg00qf 4548 29 term term NN cord-022526-j9kg00qf 4548 30 complications complication NNS cord-022526-j9kg00qf 4548 31 such such JJ cord-022526-j9kg00qf 4548 32 as as IN cord-022526-j9kg00qf 4548 33 adhesions adhesion NNS cord-022526-j9kg00qf 4548 34 . . . cord-022526-j9kg00qf 4549 1 18 18 CD cord-022526-j9kg00qf 4549 2 , , , cord-022526-j9kg00qf 4549 3 19 19 CD cord-022526-j9kg00qf 4550 1 In in IN cord-022526-j9kg00qf 4550 2 addition addition NN cord-022526-j9kg00qf 4550 3 , , , cord-022526-j9kg00qf 4550 4 the the DT cord-022526-j9kg00qf 4550 5 prognosis prognosis NN cord-022526-j9kg00qf 4550 6 is be VBZ cord-022526-j9kg00qf 4550 7 particularly particularly RB cord-022526-j9kg00qf 4550 8 low low JJ cord-022526-j9kg00qf 4550 9 for for IN cord-022526-j9kg00qf 4550 10 some some DT cord-022526-j9kg00qf 4550 11 forms form NNS cord-022526-j9kg00qf 4550 12 of of IN cord-022526-j9kg00qf 4550 13 strangulation strangulation NN cord-022526-j9kg00qf 4550 14 , , , cord-022526-j9kg00qf 4550 15 including include VBG cord-022526-j9kg00qf 4550 16 entrapment entrapment NN cord-022526-j9kg00qf 4550 17 of of IN cord-022526-j9kg00qf 4550 18 small small JJ cord-022526-j9kg00qf 4550 19 intestine intestine NN cord-022526-j9kg00qf 4550 20 within within IN cord-022526-j9kg00qf 4550 21 a a DT cord-022526-j9kg00qf 4550 22 mesenteric mesenteric JJ cord-022526-j9kg00qf 4550 23 rent rent NN cord-022526-j9kg00qf 4550 24 . . . cord-022526-j9kg00qf 4551 1 20 20 CD cord-022526-j9kg00qf 4552 1 The the DT cord-022526-j9kg00qf 4552 2 epiploic epiploic JJ cord-022526-j9kg00qf 4552 3 foramen foramen NN cord-022526-j9kg00qf 4552 4 is be VBZ cord-022526-j9kg00qf 4552 5 a a DT cord-022526-j9kg00qf 4552 6 potential potential JJ cord-022526-j9kg00qf 4552 7 opening opening NN cord-022526-j9kg00qf 4552 8 ( ( -LRB- cord-022526-j9kg00qf 4552 9 because because IN cord-022526-j9kg00qf 4552 10 the the DT cord-022526-j9kg00qf 4552 11 walls wall NNS cord-022526-j9kg00qf 4552 12 of of IN cord-022526-j9kg00qf 4552 13 the the DT cord-022526-j9kg00qf 4552 14 foramen foramen NN cord-022526-j9kg00qf 4552 15 are be VBP cord-022526-j9kg00qf 4552 16 usually usually RB cord-022526-j9kg00qf 4552 17 in in IN cord-022526-j9kg00qf 4552 18 contact contact NN cord-022526-j9kg00qf 4552 19 ) ) -RRB- cord-022526-j9kg00qf 4552 20 to to IN cord-022526-j9kg00qf 4552 21 the the DT cord-022526-j9kg00qf 4552 22 omental omental JJ cord-022526-j9kg00qf 4552 23 bursa bursa NN cord-022526-j9kg00qf 4552 24 located locate VBN cord-022526-j9kg00qf 4552 25 within within IN cord-022526-j9kg00qf 4552 26 the the DT cord-022526-j9kg00qf 4552 27 right right JJ cord-022526-j9kg00qf 4552 28 cranial cranial JJ cord-022526-j9kg00qf 4552 29 quadrant quadrant NN cord-022526-j9kg00qf 4552 30 of of IN cord-022526-j9kg00qf 4552 31 the the DT cord-022526-j9kg00qf 4552 32 abdomen abdomen NN cord-022526-j9kg00qf 4552 33 . . . cord-022526-j9kg00qf 4553 1 The the DT cord-022526-j9kg00qf 4553 2 foramen foramen NN cord-022526-j9kg00qf 4553 3 thus thus RB cord-022526-j9kg00qf 4553 4 is be VBZ cord-022526-j9kg00qf 4553 5 bounded bound VBN cord-022526-j9kg00qf 4553 6 dorsally dorsally RB cord-022526-j9kg00qf 4553 7 by by IN cord-022526-j9kg00qf 4553 8 the the DT cord-022526-j9kg00qf 4553 9 caudate caudate NN cord-022526-j9kg00qf 4553 10 process process NN cord-022526-j9kg00qf 4553 11 of of IN cord-022526-j9kg00qf 4553 12 the the DT cord-022526-j9kg00qf 4553 13 liver liver NN cord-022526-j9kg00qf 4553 14 and and CC cord-022526-j9kg00qf 4553 15 caudal caudal JJ cord-022526-j9kg00qf 4553 16 vena vena FW cord-022526-j9kg00qf 4553 17 cava cava NN cord-022526-j9kg00qf 4553 18 and and CC cord-022526-j9kg00qf 4553 19 ventrally ventrally RB cord-022526-j9kg00qf 4553 20 by by IN cord-022526-j9kg00qf 4553 21 the the DT cord-022526-j9kg00qf 4553 22 pancreas pancrea NNS cord-022526-j9kg00qf 4553 23 , , , cord-022526-j9kg00qf 4553 24 hepatoduodenal hepatoduodenal JJ cord-022526-j9kg00qf 4553 25 ligament ligament NN cord-022526-j9kg00qf 4553 26 , , , cord-022526-j9kg00qf 4553 27 and and CC cord-022526-j9kg00qf 4553 28 portal portal JJ cord-022526-j9kg00qf 4553 29 vein vein NN cord-022526-j9kg00qf 4553 30 . . . cord-022526-j9kg00qf 4554 1 Intestine intestine NN cord-022526-j9kg00qf 4554 2 may may MD cord-022526-j9kg00qf 4554 3 enter enter VB cord-022526-j9kg00qf 4554 4 the the DT cord-022526-j9kg00qf 4554 5 foramen foramen NN cord-022526-j9kg00qf 4554 6 from from IN cord-022526-j9kg00qf 4554 7 the the DT cord-022526-j9kg00qf 4554 8 visceral visceral JJ cord-022526-j9kg00qf 4554 9 surface surface NN cord-022526-j9kg00qf 4554 10 of of IN cord-022526-j9kg00qf 4554 11 the the DT cord-022526-j9kg00qf 4554 12 liver liver NN cord-022526-j9kg00qf 4554 13 toward toward IN cord-022526-j9kg00qf 4554 14 the the DT cord-022526-j9kg00qf 4554 15 right right JJ cord-022526-j9kg00qf 4554 16 body body NN cord-022526-j9kg00qf 4554 17 wall wall NN cord-022526-j9kg00qf 4554 18 or or CC cord-022526-j9kg00qf 4554 19 the the DT cord-022526-j9kg00qf 4554 20 opposite opposite JJ cord-022526-j9kg00qf 4554 21 direction direction NN cord-022526-j9kg00qf 4554 22 . . . cord-022526-j9kg00qf 4555 1 Studies study NNS cord-022526-j9kg00qf 4555 2 differ differ VBP cord-022526-j9kg00qf 4555 3 as as IN cord-022526-j9kg00qf 4555 4 to to TO cord-022526-j9kg00qf 4555 5 which which WDT cord-022526-j9kg00qf 4555 6 is be VBZ cord-022526-j9kg00qf 4555 7 the the DT cord-022526-j9kg00qf 4555 8 most most RBS cord-022526-j9kg00qf 4555 9 common common JJ cord-022526-j9kg00qf 4555 10 form form NN cord-022526-j9kg00qf 4555 11 . . . cord-022526-j9kg00qf 4556 1 12 12 CD cord-022526-j9kg00qf 4556 2 , , , cord-022526-j9kg00qf 4556 3 21 21 CD cord-022526-j9kg00qf 4557 1 In in IN cord-022526-j9kg00qf 4557 2 the the DT cord-022526-j9kg00qf 4557 3 case case NN cord-022526-j9kg00qf 4557 4 of of IN cord-022526-j9kg00qf 4557 5 entrapments entrapment NNS cord-022526-j9kg00qf 4557 6 that that WDT cord-022526-j9kg00qf 4557 7 enter enter VBP cord-022526-j9kg00qf 4557 8 the the DT cord-022526-j9kg00qf 4557 9 foramen foramen NN cord-022526-j9kg00qf 4557 10 in in IN cord-022526-j9kg00qf 4557 11 a a DT cord-022526-j9kg00qf 4557 12 left left JJ cord-022526-j9kg00qf 4557 13 - - HYPH cord-022526-j9kg00qf 4557 14 to to IN cord-022526-j9kg00qf 4557 15 - - HYPH cord-022526-j9kg00qf 4557 16 right right JJ cord-022526-j9kg00qf 4557 17 direction direction NN cord-022526-j9kg00qf 4557 18 , , , cord-022526-j9kg00qf 4557 19 the the DT cord-022526-j9kg00qf 4557 20 omental omental JJ cord-022526-j9kg00qf 4557 21 bursa bursa NN cord-022526-j9kg00qf 4557 22 ruptures rupture VBZ cord-022526-j9kg00qf 4557 23 as as IN cord-022526-j9kg00qf 4557 24 the the DT cord-022526-j9kg00qf 4557 25 intestine intestine NN cord-022526-j9kg00qf 4557 26 migrates migrate VBZ cord-022526-j9kg00qf 4557 27 through through IN cord-022526-j9kg00qf 4557 28 the the DT cord-022526-j9kg00qf 4557 29 epiploic epiploic NN cord-022526-j9kg00qf 4557 30 foramen foramen NN cord-022526-j9kg00qf 4557 31 , , , cord-022526-j9kg00qf 4557 32 which which WDT cord-022526-j9kg00qf 4557 33 may may MD cord-022526-j9kg00qf 4557 34 contribute contribute VB cord-022526-j9kg00qf 4557 35 to to IN cord-022526-j9kg00qf 4557 36 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 4557 37 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4557 38 often often RB cord-022526-j9kg00qf 4557 39 seen see VBN cord-022526-j9kg00qf 4557 40 with with IN cord-022526-j9kg00qf 4557 41 this this DT cord-022526-j9kg00qf 4557 42 condition condition NN cord-022526-j9kg00qf 4557 43 . . . cord-022526-j9kg00qf 4558 1 Clinical clinical JJ cord-022526-j9kg00qf 4558 2 signs sign NNS cord-022526-j9kg00qf 4558 3 include include VBP cord-022526-j9kg00qf 4558 4 acute acute JJ cord-022526-j9kg00qf 4558 5 onset onset NN cord-022526-j9kg00qf 4558 6 of of IN cord-022526-j9kg00qf 4558 7 severe severe JJ cord-022526-j9kg00qf 4558 8 colic colic NN cord-022526-j9kg00qf 4558 9 with with IN cord-022526-j9kg00qf 4558 10 examination examination NN cord-022526-j9kg00qf 4558 11 findings finding NNS cord-022526-j9kg00qf 4558 12 compatible compatible JJ cord-022526-j9kg00qf 4558 13 with with IN cord-022526-j9kg00qf 4558 14 small small JJ cord-022526-j9kg00qf 4558 15 intestinal intestinal JJ cord-022526-j9kg00qf 4558 16 obstruction obstruction NN cord-022526-j9kg00qf 4558 17 . . . cord-022526-j9kg00qf 4559 1 The the DT cord-022526-j9kg00qf 4559 2 condition condition NN cord-022526-j9kg00qf 4559 3 tends tend VBZ cord-022526-j9kg00qf 4559 4 to to TO cord-022526-j9kg00qf 4559 5 be be VB cord-022526-j9kg00qf 4559 6 more more RBR cord-022526-j9kg00qf 4559 7 prevalent prevalent JJ cord-022526-j9kg00qf 4559 8 in in IN cord-022526-j9kg00qf 4559 9 older old JJR cord-022526-j9kg00qf 4559 10 horses horse NNS cord-022526-j9kg00qf 4559 11 , , , cord-022526-j9kg00qf 4559 12 12 12 CD cord-022526-j9kg00qf 4559 13 possibly possibly RB cord-022526-j9kg00qf 4559 14 because because IN cord-022526-j9kg00qf 4559 15 of of IN cord-022526-j9kg00qf 4559 16 enlargement enlargement NN cord-022526-j9kg00qf 4559 17 of of IN cord-022526-j9kg00qf 4559 18 the the DT cord-022526-j9kg00qf 4559 19 epiploic epiploic JJ cord-022526-j9kg00qf 4559 20 foramen foramen NN cord-022526-j9kg00qf 4559 21 as as IN cord-022526-j9kg00qf 4559 22 the the DT cord-022526-j9kg00qf 4559 23 right right JJ cord-022526-j9kg00qf 4559 24 lobe lobe NN cord-022526-j9kg00qf 4559 25 of of IN cord-022526-j9kg00qf 4559 26 the the DT cord-022526-j9kg00qf 4559 27 liver liver NN cord-022526-j9kg00qf 4559 28 undergoes undergo VBZ cord-022526-j9kg00qf 4559 29 ageassociated ageassociate VBN cord-022526-j9kg00qf 4559 30 atrophy atrophy NN cord-022526-j9kg00qf 4559 31 . . . cord-022526-j9kg00qf 4560 1 22 22 CD cord-022526-j9kg00qf 4561 1 However however RB cord-022526-j9kg00qf 4561 2 , , , cord-022526-j9kg00qf 4561 3 the the DT cord-022526-j9kg00qf 4561 4 disease disease NN cord-022526-j9kg00qf 4561 5 also also RB cord-022526-j9kg00qf 4561 6 has have VBZ cord-022526-j9kg00qf 4561 7 been be VBN cord-022526-j9kg00qf 4561 8 recognized recognize VBN cord-022526-j9kg00qf 4561 9 in in IN cord-022526-j9kg00qf 4561 10 foals foal NNS cord-022526-j9kg00qf 4561 11 as as RB cord-022526-j9kg00qf 4561 12 young young JJ cord-022526-j9kg00qf 4561 13 as as IN cord-022526-j9kg00qf 4561 14 4 4 CD cord-022526-j9kg00qf 4561 15 months month NNS cord-022526-j9kg00qf 4561 16 of of IN cord-022526-j9kg00qf 4561 17 age age NN cord-022526-j9kg00qf 4561 18 . . . cord-022526-j9kg00qf 4562 1 23 23 CD cord-022526-j9kg00qf 4563 1 One one PRP cord-022526-j9kg00qf 4563 2 makes make VBZ cord-022526-j9kg00qf 4563 3 a a DT cord-022526-j9kg00qf 4563 4 definitive definitive JJ cord-022526-j9kg00qf 4563 5 diagnosis diagnosis NN cord-022526-j9kg00qf 4563 6 at at IN cord-022526-j9kg00qf 4563 7 surgery surgery NN cord-022526-j9kg00qf 4563 8 , , , cord-022526-j9kg00qf 4563 9 although although IN cord-022526-j9kg00qf 4563 10 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 4563 11 findings finding NNS cord-022526-j9kg00qf 4563 12 of of IN cord-022526-j9kg00qf 4563 13 distended distended JJ cord-022526-j9kg00qf 4563 14 loops loop NNS cord-022526-j9kg00qf 4563 15 of of IN cord-022526-j9kg00qf 4563 16 edematous edematous JJ cord-022526-j9kg00qf 4563 17 small small JJ cord-022526-j9kg00qf 4563 18 intestine intestine NN cord-022526-j9kg00qf 4563 19 adjacent adjacent JJ cord-022526-j9kg00qf 4563 20 to to IN cord-022526-j9kg00qf 4563 21 the the DT cord-022526-j9kg00qf 4563 22 right right JJ cord-022526-j9kg00qf 4563 23 middle middle JJ cord-022526-j9kg00qf 4563 24 body body NN cord-022526-j9kg00qf 4563 25 wall wall NN cord-022526-j9kg00qf 4563 26 suggest suggest VBP cord-022526-j9kg00qf 4563 27 epiploic epiploic NNP cord-022526-j9kg00qf 4563 28 foramen foramen NN cord-022526-j9kg00qf 4563 29 entrapment entrapment NN cord-022526-j9kg00qf 4563 30 . . . cord-022526-j9kg00qf 4564 1 12 12 CD cord-022526-j9kg00qf 4565 1 In in IN cord-022526-j9kg00qf 4565 2 general general JJ cord-022526-j9kg00qf 4565 3 , , , cord-022526-j9kg00qf 4565 4 thickened thickened JJ cord-022526-j9kg00qf 4565 5 , , , cord-022526-j9kg00qf 4565 6 amotile amotile JJ cord-022526-j9kg00qf 4565 7 intestine intestine NN cord-022526-j9kg00qf 4565 8 on on IN cord-022526-j9kg00qf 4565 9 ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 4565 10 examination examination NN cord-022526-j9kg00qf 4565 11 is be VBZ cord-022526-j9kg00qf 4565 12 highly highly RB cord-022526-j9kg00qf 4565 13 predictive predictive JJ cord-022526-j9kg00qf 4565 14 for for IN cord-022526-j9kg00qf 4565 15 small small JJ cord-022526-j9kg00qf 4565 16 intestinal intestinal JJ cord-022526-j9kg00qf 4565 17 strangulating strangulating JJ cord-022526-j9kg00qf 4565 18 obstruction obstruction NN cord-022526-j9kg00qf 4565 19 . . . cord-022526-j9kg00qf 4566 1 24 24 CD cord-022526-j9kg00qf 4566 2 Small small JJ cord-022526-j9kg00qf 4566 3 intestine intestine NN cord-022526-j9kg00qf 4566 4 entrapped entrap VBN cord-022526-j9kg00qf 4566 5 in in IN cord-022526-j9kg00qf 4566 6 the the DT cord-022526-j9kg00qf 4566 7 epiploic epiploic JJ cord-022526-j9kg00qf 4566 8 foramen foramen NN cord-022526-j9kg00qf 4566 9 may may MD cord-022526-j9kg00qf 4566 10 be be VB cord-022526-j9kg00qf 4566 11 limited limit VBN cord-022526-j9kg00qf 4566 12 to to IN cord-022526-j9kg00qf 4566 13 a a DT cord-022526-j9kg00qf 4566 14 portion portion NN cord-022526-j9kg00qf 4566 15 of of IN cord-022526-j9kg00qf 4566 16 the the DT cord-022526-j9kg00qf 4566 17 intestinal intestinal JJ cord-022526-j9kg00qf 4566 18 wall wall NN cord-022526-j9kg00qf 4566 19 ( ( -LRB- cord-022526-j9kg00qf 4566 20 parietal parietal NNP cord-022526-j9kg00qf 4566 21 hernia hernia NNP cord-022526-j9kg00qf 4566 22 ) ) -RRB- cord-022526-j9kg00qf 4566 23 , , . cord-022526-j9kg00qf 4567 1 25 25 CD cord-022526-j9kg00qf 4567 2 and and CC cord-022526-j9kg00qf 4567 3 the the DT cord-022526-j9kg00qf 4567 4 large large JJ cord-022526-j9kg00qf 4567 5 colon colon NN cord-022526-j9kg00qf 4567 6 may may MD cord-022526-j9kg00qf 4567 7 become become VB cord-022526-j9kg00qf 4567 8 entrapped entrap VBN cord-022526-j9kg00qf 4567 9 within within IN cord-022526-j9kg00qf 4567 10 the the DT cord-022526-j9kg00qf 4567 11 epiploic epiploic JJ cord-022526-j9kg00qf 4567 12 foramen foramen NN cord-022526-j9kg00qf 4567 13 . . . cord-022526-j9kg00qf 4568 1 26 26 CD cord-022526-j9kg00qf 4569 1 In in IN cord-022526-j9kg00qf 4569 2 treating treat VBG cord-022526-j9kg00qf 4569 3 epiploic epiploic NN cord-022526-j9kg00qf 4569 4 foramen foramen NN cord-022526-j9kg00qf 4569 5 entrapment entrapment NN cord-022526-j9kg00qf 4569 6 , , , cord-022526-j9kg00qf 4569 7 one one PRP cord-022526-j9kg00qf 4569 8 must must MD cord-022526-j9kg00qf 4569 9 not not RB cord-022526-j9kg00qf 4569 10 enlarge enlarge VB cord-022526-j9kg00qf 4569 11 the the DT cord-022526-j9kg00qf 4569 12 epiploic epiploic JJ cord-022526-j9kg00qf 4569 13 foramen foramen NN cord-022526-j9kg00qf 4569 14 by by IN cord-022526-j9kg00qf 4569 15 blunt blunt JJ cord-022526-j9kg00qf 4569 16 force force NN cord-022526-j9kg00qf 4569 17 or or CC cord-022526-j9kg00qf 4569 18 with with IN cord-022526-j9kg00qf 4569 19 a a DT cord-022526-j9kg00qf 4569 20 sharp sharp JJ cord-022526-j9kg00qf 4569 21 instrument instrument NN cord-022526-j9kg00qf 4569 22 , , , cord-022526-j9kg00qf 4569 23 because because IN cord-022526-j9kg00qf 4569 24 rupture rupture NN cord-022526-j9kg00qf 4569 25 of of IN cord-022526-j9kg00qf 4569 26 the the DT cord-022526-j9kg00qf 4569 27 vena vena NNP cord-022526-j9kg00qf 4569 28 cava cava NNP cord-022526-j9kg00qf 4569 29 or or CC cord-022526-j9kg00qf 4569 30 portal portal JJ cord-022526-j9kg00qf 4569 31 vein vein NN cord-022526-j9kg00qf 4569 32 and and CC cord-022526-j9kg00qf 4569 33 fatal fatal JJ cord-022526-j9kg00qf 4569 34 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4569 35 may may MD cord-022526-j9kg00qf 4569 36 occur occur VB cord-022526-j9kg00qf 4569 37 . . . cord-022526-j9kg00qf 4570 1 Prognosis prognosis NN cord-022526-j9kg00qf 4570 2 has have VBZ cord-022526-j9kg00qf 4570 3 improved improve VBN cord-022526-j9kg00qf 4570 4 substantially substantially RB cord-022526-j9kg00qf 4570 5 over over IN cord-022526-j9kg00qf 4570 6 the the DT cord-022526-j9kg00qf 4570 7 last last JJ cord-022526-j9kg00qf 4570 8 decade decade NN cord-022526-j9kg00qf 4570 9 , , , cord-022526-j9kg00qf 4570 10 with with IN cord-022526-j9kg00qf 4570 11 current current JJ cord-022526-j9kg00qf 4570 12 short short JJ cord-022526-j9kg00qf 4570 13 - - HYPH cord-022526-j9kg00qf 4570 14 term term NN cord-022526-j9kg00qf 4570 15 survival survival NN cord-022526-j9kg00qf 4570 16 rates rate NNS cord-022526-j9kg00qf 4570 17 ( ( -LRB- cord-022526-j9kg00qf 4570 18 discharge discharge NN cord-022526-j9kg00qf 4570 19 from from IN cord-022526-j9kg00qf 4570 20 the the DT cord-022526-j9kg00qf 4570 21 hospital hospital NN cord-022526-j9kg00qf 4570 22 ) ) -RRB- cord-022526-j9kg00qf 4570 23 ranging range VBG cord-022526-j9kg00qf 4570 24 from from IN cord-022526-j9kg00qf 4570 25 74 74 CD cord-022526-j9kg00qf 4570 26 % % NN cord-022526-j9kg00qf 4570 27 27 27 CD cord-022526-j9kg00qf 4570 28 to to TO cord-022526-j9kg00qf 4570 29 79 79 CD cord-022526-j9kg00qf 4570 30 % % NN cord-022526-j9kg00qf 4570 31 . . . cord-022526-j9kg00qf 4571 1 12 12 CD cord-022526-j9kg00qf 4572 1 Preoperative preoperative JJ cord-022526-j9kg00qf 4572 2 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4572 3 has have VBZ cord-022526-j9kg00qf 4572 4 been be VBN cord-022526-j9kg00qf 4572 5 found find VBN cord-022526-j9kg00qf 4572 6 consistently consistently RB cord-022526-j9kg00qf 4572 7 to to TO cord-022526-j9kg00qf 4572 8 be be VB cord-022526-j9kg00qf 4572 9 the the DT cord-022526-j9kg00qf 4572 10 most most RBS cord-022526-j9kg00qf 4572 11 predictive predictive JJ cord-022526-j9kg00qf 4572 12 test test NN cord-022526-j9kg00qf 4572 13 of of IN cord-022526-j9kg00qf 4572 14 postoperative postoperative JJ cord-022526-j9kg00qf 4572 15 survival survival NN cord-022526-j9kg00qf 4572 16 . . . cord-022526-j9kg00qf 4573 1 12,27 12,27 CD cord-022526-j9kg00qf 4573 2 Lipomata Lipomata NNP cord-022526-j9kg00qf 4573 3 form form NN cord-022526-j9kg00qf 4573 4 between between IN cord-022526-j9kg00qf 4573 5 the the DT cord-022526-j9kg00qf 4573 6 leaves leave NNS cord-022526-j9kg00qf 4573 7 of of IN cord-022526-j9kg00qf 4573 8 the the DT cord-022526-j9kg00qf 4573 9 mesentery mesentery NN cord-022526-j9kg00qf 4573 10 as as IN cord-022526-j9kg00qf 4573 11 horses horse NNS cord-022526-j9kg00qf 4573 12 age age VBP cord-022526-j9kg00qf 4573 13 and and CC cord-022526-j9kg00qf 4573 14 develop develop VB cord-022526-j9kg00qf 4573 15 mesenteric mesenteric JJ cord-022526-j9kg00qf 4573 16 stalks stalk NNS cord-022526-j9kg00qf 4573 17 as as IN cord-022526-j9kg00qf 4573 18 the the DT cord-022526-j9kg00qf 4573 19 weight weight NN cord-022526-j9kg00qf 4573 20 of of IN cord-022526-j9kg00qf 4573 21 the the DT cord-022526-j9kg00qf 4573 22 lipoma lipoma NN cord-022526-j9kg00qf 4573 23 tugs tug VBZ cord-022526-j9kg00qf 4573 24 on on IN cord-022526-j9kg00qf 4573 25 the the DT cord-022526-j9kg00qf 4573 26 mesentery mesentery NN cord-022526-j9kg00qf 4573 27 . . . cord-022526-j9kg00qf 4574 1 The the DT cord-022526-j9kg00qf 4574 2 stalk stalk NN cord-022526-j9kg00qf 4574 3 of of IN cord-022526-j9kg00qf 4574 4 the the DT cord-022526-j9kg00qf 4574 5 lipoma lipoma NN cord-022526-j9kg00qf 4574 6 subsequently subsequently RB cord-022526-j9kg00qf 4574 7 may may MD cord-022526-j9kg00qf 4574 8 wrap wrap VB cord-022526-j9kg00qf 4574 9 around around RP cord-022526-j9kg00qf 4574 10 a a DT cord-022526-j9kg00qf 4574 11 loop loop NN cord-022526-j9kg00qf 4574 12 of of IN cord-022526-j9kg00qf 4574 13 small small JJ cord-022526-j9kg00qf 4574 14 intestine intestine NN cord-022526-j9kg00qf 4574 15 or or CC cord-022526-j9kg00qf 4574 16 small small JJ cord-022526-j9kg00qf 4574 17 colon colon NN cord-022526-j9kg00qf 4574 18 causing cause VBG cord-022526-j9kg00qf 4574 19 strangulation strangulation NN cord-022526-j9kg00qf 4574 20 . . . cord-022526-j9kg00qf 4575 1 One one PRP cord-022526-j9kg00qf 4575 2 should should MD cord-022526-j9kg00qf 4575 3 suspect suspect VB cord-022526-j9kg00qf 4575 4 strangulating strangulating JJ cord-022526-j9kg00qf 4575 5 lipomata lipomata NN cord-022526-j9kg00qf 4575 6 in in IN cord-022526-j9kg00qf 4575 7 aged aged JJ cord-022526-j9kg00qf 4575 8 ( ( -LRB- cord-022526-j9kg00qf 4575 9 > > NFP cord-022526-j9kg00qf 4575 10 15 15 CD cord-022526-j9kg00qf 4575 11 years year NNS cord-022526-j9kg00qf 4575 12 old old JJ cord-022526-j9kg00qf 4575 13 ) ) -RRB- cord-022526-j9kg00qf 4575 14 geldings gelding NNS cord-022526-j9kg00qf 4575 15 with with IN cord-022526-j9kg00qf 4575 16 acute acute JJ cord-022526-j9kg00qf 4575 17 colic colic NN cord-022526-j9kg00qf 4575 18 referable referable JJ cord-022526-j9kg00qf 4575 19 to to IN cord-022526-j9kg00qf 4575 20 the the DT cord-022526-j9kg00qf 4575 21 small small JJ cord-022526-j9kg00qf 4575 22 intestinal intestinal JJ cord-022526-j9kg00qf 4575 23 tract tract NN cord-022526-j9kg00qf 4575 24 . . . cord-022526-j9kg00qf 4576 1 28 28 CD cord-022526-j9kg00qf 4576 2 , , , cord-022526-j9kg00qf 4576 3 29 29 CD cord-022526-j9kg00qf 4576 4 Ponies Ponies NNPS cord-022526-j9kg00qf 4576 5 also also RB cord-022526-j9kg00qf 4576 6 appear appear VBP cord-022526-j9kg00qf 4576 7 to to TO cord-022526-j9kg00qf 4576 8 be be VB cord-022526-j9kg00qf 4576 9 at at IN cord-022526-j9kg00qf 4576 10 risk risk NN cord-022526-j9kg00qf 4576 11 of of IN cord-022526-j9kg00qf 4576 12 developing develop VBG cord-022526-j9kg00qf 4576 13 disease disease NN cord-022526-j9kg00qf 4576 14 , , , cord-022526-j9kg00qf 4576 15 29 29 CD cord-022526-j9kg00qf 4576 16 suggesting suggest VBG cord-022526-j9kg00qf 4576 17 alterations alteration NNS cord-022526-j9kg00qf 4576 18 in in IN cord-022526-j9kg00qf 4576 19 fat fat JJ cord-022526-j9kg00qf 4576 20 metabolism metabolism NN cord-022526-j9kg00qf 4576 21 may may MD cord-022526-j9kg00qf 4576 22 predispose predispose VB cord-022526-j9kg00qf 4576 23 certain certain JJ cord-022526-j9kg00qf 4576 24 horses horse NNS cord-022526-j9kg00qf 4576 25 to to IN cord-022526-j9kg00qf 4576 26 development development NN cord-022526-j9kg00qf 4576 27 of of IN cord-022526-j9kg00qf 4576 28 mesenteric mesenteric JJ cord-022526-j9kg00qf 4576 29 lipomata lipomata NN cord-022526-j9kg00qf 4576 30 . . . cord-022526-j9kg00qf 4577 1 One one CD cord-022526-j9kg00qf 4577 2 usually usually RB cord-022526-j9kg00qf 4577 3 makes make VBZ cord-022526-j9kg00qf 4577 4 the the DT cord-022526-j9kg00qf 4577 5 diagnosis diagnosis NN cord-022526-j9kg00qf 4577 6 at at IN cord-022526-j9kg00qf 4577 7 surgery surgery NN cord-022526-j9kg00qf 4577 8 , , , cord-022526-j9kg00qf 4577 9 although although IN cord-022526-j9kg00qf 4577 10 on on IN cord-022526-j9kg00qf 4577 11 rare rare JJ cord-022526-j9kg00qf 4577 12 occasions occasion NNS cord-022526-j9kg00qf 4577 13 one one PRP cord-022526-j9kg00qf 4577 14 can can MD cord-022526-j9kg00qf 4577 15 palpate palpate VB cord-022526-j9kg00qf 4577 16 a a DT cord-022526-j9kg00qf 4577 17 lipoma lipoma NN cord-022526-j9kg00qf 4577 18 per per IN cord-022526-j9kg00qf 4577 19 rectum rectum NN cord-022526-j9kg00qf 4577 20 . . . cord-022526-j9kg00qf 4578 1 30 30 CD cord-022526-j9kg00qf 4578 2 Treatment treatment NN cord-022526-j9kg00qf 4578 3 involves involve VBZ cord-022526-j9kg00qf 4578 4 surgical surgical JJ cord-022526-j9kg00qf 4578 5 resection resection NN cord-022526-j9kg00qf 4578 6 of of IN cord-022526-j9kg00qf 4578 7 the the DT cord-022526-j9kg00qf 4578 8 lipoma lipoma NN cord-022526-j9kg00qf 4578 9 and and CC cord-022526-j9kg00qf 4578 10 strangulated strangulated JJ cord-022526-j9kg00qf 4578 11 bowel bowel NN cord-022526-j9kg00qf 4578 12 , , , cord-022526-j9kg00qf 4578 13 although although IN cord-022526-j9kg00qf 4578 14 strangulated strangulated JJ cord-022526-j9kg00qf 4578 15 intestine intestine NN cord-022526-j9kg00qf 4578 16 is be VBZ cord-022526-j9kg00qf 4578 17 not not RB cord-022526-j9kg00qf 4578 18 always always RB cord-022526-j9kg00qf 4578 19 nonviable nonviable JJ cord-022526-j9kg00qf 4578 20 . . . cord-022526-j9kg00qf 4579 1 28 28 CD cord-022526-j9kg00qf 4579 2 Studies study NNS cord-022526-j9kg00qf 4579 3 indicate indicate VBP cord-022526-j9kg00qf 4579 4 that that IN cord-022526-j9kg00qf 4579 5 approximately approximately RB cord-022526-j9kg00qf 4579 6 50 50 CD cord-022526-j9kg00qf 4579 7 % % NN cord-022526-j9kg00qf 4579 8 29 29 CD cord-022526-j9kg00qf 4579 9 to to TO cord-022526-j9kg00qf 4579 10 80 80 CD cord-022526-j9kg00qf 4579 11 % % NN cord-022526-j9kg00qf 4579 12 28 28 CD cord-022526-j9kg00qf 4579 13 of of IN cord-022526-j9kg00qf 4579 14 horses horse NNS cord-022526-j9kg00qf 4579 15 are be VBP cord-022526-j9kg00qf 4579 16 discharged discharge VBN cord-022526-j9kg00qf 4579 17 from from IN cord-022526-j9kg00qf 4579 18 the the DT cord-022526-j9kg00qf 4579 19 hospital hospital NN cord-022526-j9kg00qf 4579 20 following follow VBG cord-022526-j9kg00qf 4579 21 surgical surgical JJ cord-022526-j9kg00qf 4579 22 treatment treatment NN cord-022526-j9kg00qf 4579 23 . . . cord-022526-j9kg00qf 4580 1 A a DT cord-022526-j9kg00qf 4580 2 volvulus volvulus NN cord-022526-j9kg00qf 4580 3 is be VBZ cord-022526-j9kg00qf 4580 4 a a DT cord-022526-j9kg00qf 4580 5 twist twist NN cord-022526-j9kg00qf 4580 6 along along IN cord-022526-j9kg00qf 4580 7 the the DT cord-022526-j9kg00qf 4580 8 axis axis NN cord-022526-j9kg00qf 4580 9 of of IN cord-022526-j9kg00qf 4580 10 the the DT cord-022526-j9kg00qf 4580 11 mesentery mesentery NN cord-022526-j9kg00qf 4580 12 , , , cord-022526-j9kg00qf 4580 13 whereas whereas IN cord-022526-j9kg00qf 4580 14 torsion torsion NN cord-022526-j9kg00qf 4580 15 is be VBZ cord-022526-j9kg00qf 4580 16 a a DT cord-022526-j9kg00qf 4580 17 twist twist NN cord-022526-j9kg00qf 4580 18 along along IN cord-022526-j9kg00qf 4580 19 the the DT cord-022526-j9kg00qf 4580 20 longitudinal longitudinal JJ cord-022526-j9kg00qf 4580 21 axis axis NN cord-022526-j9kg00qf 4580 22 of of IN cord-022526-j9kg00qf 4580 23 the the DT cord-022526-j9kg00qf 4580 24 intestine intestine NN cord-022526-j9kg00qf 4580 25 . . . cord-022526-j9kg00qf 4581 1 Small small JJ cord-022526-j9kg00qf 4581 2 intestinal intestinal JJ cord-022526-j9kg00qf 4581 3 volvulus volvulus NN cord-022526-j9kg00qf 4581 4 theoretically theoretically RB cord-022526-j9kg00qf 4581 5 is be VBZ cord-022526-j9kg00qf 4581 6 initiated initiate VBN cord-022526-j9kg00qf 4581 7 by by IN cord-022526-j9kg00qf 4581 8 a a DT cord-022526-j9kg00qf 4581 9 change change NN cord-022526-j9kg00qf 4581 10 in in IN cord-022526-j9kg00qf 4581 11 local local JJ cord-022526-j9kg00qf 4581 12 peristalsis peristalsis NN cord-022526-j9kg00qf 4581 13 or or CC cord-022526-j9kg00qf 4581 14 the the DT cord-022526-j9kg00qf 4581 15 occurrence occurrence NN cord-022526-j9kg00qf 4581 16 of of IN cord-022526-j9kg00qf 4581 17 a a DT cord-022526-j9kg00qf 4581 18 lesion lesion NN cord-022526-j9kg00qf 4581 19 around around IN cord-022526-j9kg00qf 4581 20 which which WDT cord-022526-j9kg00qf 4581 21 the the DT cord-022526-j9kg00qf 4581 22 intestine intestine NN cord-022526-j9kg00qf 4581 23 and and CC cord-022526-j9kg00qf 4581 24 its -PRON- PRP$ cord-022526-j9kg00qf 4581 25 mesentery mesentery NN cord-022526-j9kg00qf 4581 26 may may MD cord-022526-j9kg00qf 4581 27 twist twist VB cord-022526-j9kg00qf 4581 28 ( ( -LRB- cord-022526-j9kg00qf 4581 29 such such JJ cord-022526-j9kg00qf 4581 30 as as IN cord-022526-j9kg00qf 4581 31 an an DT cord-022526-j9kg00qf 4581 32 ascarid ascarid JJ cord-022526-j9kg00qf 4581 33 impaction impaction NN cord-022526-j9kg00qf 4581 34 ) ) -RRB- cord-022526-j9kg00qf 4581 35 . . . cord-022526-j9kg00qf 4582 1 11 11 CD cord-022526-j9kg00qf 4582 2 Volvulus Volvulus NNP cord-022526-j9kg00qf 4582 3 is be VBZ cord-022526-j9kg00qf 4582 4 reportedly reportedly RB cord-022526-j9kg00qf 4582 5 one one CD cord-022526-j9kg00qf 4582 6 of of IN cord-022526-j9kg00qf 4582 7 the the DT cord-022526-j9kg00qf 4582 8 most most RBS cord-022526-j9kg00qf 4582 9 commonly commonly RB cord-022526-j9kg00qf 4582 10 diagnosed diagnose VBN cord-022526-j9kg00qf 4582 11 causes cause NNS cord-022526-j9kg00qf 4582 12 of of IN cord-022526-j9kg00qf 4582 13 small small JJ cord-022526-j9kg00qf 4582 14 intestinal intestinal JJ cord-022526-j9kg00qf 4582 15 obstruction obstruction NN cord-022526-j9kg00qf 4582 16 in in IN cord-022526-j9kg00qf 4582 17 foals foal NNS cord-022526-j9kg00qf 4582 18 . . . cord-022526-j9kg00qf 4583 1 31 31 CD cord-022526-j9kg00qf 4583 2 , , , cord-022526-j9kg00qf 4583 3 32 32 CD cord-022526-j9kg00qf 4583 4 The the DT cord-022526-j9kg00qf 4583 5 theory theory NN cord-022526-j9kg00qf 4583 6 is be VBZ cord-022526-j9kg00qf 4583 7 that that IN cord-022526-j9kg00qf 4583 8 young young JJ cord-022526-j9kg00qf 4583 9 foals foal NNS cord-022526-j9kg00qf 4583 10 may may MD cord-022526-j9kg00qf 4583 11 be be VB cord-022526-j9kg00qf 4583 12 at at IN cord-022526-j9kg00qf 4583 13 risk risk NN cord-022526-j9kg00qf 4583 14 of of IN cord-022526-j9kg00qf 4583 15 small small JJ cord-022526-j9kg00qf 4583 16 intestinal intestinal JJ cord-022526-j9kg00qf 4583 17 volvulus volvulus NN cord-022526-j9kg00qf 4583 18 because because IN cord-022526-j9kg00qf 4583 19 of of IN cord-022526-j9kg00qf 4583 20 changing change VBG cord-022526-j9kg00qf 4583 21 feed feed NN cord-022526-j9kg00qf 4583 22 habits habit NNS cord-022526-j9kg00qf 4583 23 and and CC cord-022526-j9kg00qf 4583 24 adaptation adaptation NN cord-022526-j9kg00qf 4583 25 to to IN cord-022526-j9kg00qf 4583 26 a a DT cord-022526-j9kg00qf 4583 27 bulkier bulky JJR cord-022526-j9kg00qf 4583 28 adult adult NN cord-022526-j9kg00qf 4583 29 diet diet NN cord-022526-j9kg00qf 4583 30 . . . cord-022526-j9kg00qf 4584 1 Onset onset NN cord-022526-j9kg00qf 4584 2 of of IN cord-022526-j9kg00qf 4584 3 acute acute JJ cord-022526-j9kg00qf 4584 4 , , , cord-022526-j9kg00qf 4584 5 severe severe JJ cord-022526-j9kg00qf 4584 6 colic colic NN cord-022526-j9kg00qf 4584 7 , , , cord-022526-j9kg00qf 4584 8 a a DT cord-022526-j9kg00qf 4584 9 distended distended JJ cord-022526-j9kg00qf 4584 10 abdomen abdomen NN cord-022526-j9kg00qf 4584 11 , , , cord-022526-j9kg00qf 4584 12 and and CC cord-022526-j9kg00qf 4584 13 radiographic radiographic JJ cord-022526-j9kg00qf 4584 14 evidence evidence NN cord-022526-j9kg00qf 4584 15 of of IN cord-022526-j9kg00qf 4584 16 multiple multiple JJ cord-022526-j9kg00qf 4584 17 loops loop NNS cord-022526-j9kg00qf 4584 18 of of IN cord-022526-j9kg00qf 4584 19 distended distended JJ cord-022526-j9kg00qf 4584 20 small small JJ cord-022526-j9kg00qf 4584 21 intestine intestine NN cord-022526-j9kg00qf 4584 22 in in IN cord-022526-j9kg00qf 4584 23 a a DT cord-022526-j9kg00qf 4584 24 young young JJ cord-022526-j9kg00qf 4584 25 foal foal NN cord-022526-j9kg00qf 4584 26 suggest suggest VBP cord-022526-j9kg00qf 4584 27 small small JJ cord-022526-j9kg00qf 4584 28 intestinal intestinal JJ cord-022526-j9kg00qf 4584 29 volvulus volvulus NN cord-022526-j9kg00qf 4584 30 . . . cord-022526-j9kg00qf 4585 1 However however RB cord-022526-j9kg00qf 4585 2 , , , cord-022526-j9kg00qf 4585 3 one one PRP cord-022526-j9kg00qf 4585 4 can can MD cord-022526-j9kg00qf 4585 5 not not RB cord-022526-j9kg00qf 4585 6 differentiate differentiate VB cord-022526-j9kg00qf 4585 7 volvulus volvulus NN cord-022526-j9kg00qf 4585 8 from from IN cord-022526-j9kg00qf 4585 9 other other JJ cord-022526-j9kg00qf 4585 10 causes cause NNS cord-022526-j9kg00qf 4585 11 of of IN cord-022526-j9kg00qf 4585 12 small small JJ cord-022526-j9kg00qf 4585 13 intestinal intestinal JJ cord-022526-j9kg00qf 4585 14 obstruction obstruction NN cord-022526-j9kg00qf 4585 15 preoperatively preoperatively NN cord-022526-j9kg00qf 4585 16 . . . cord-022526-j9kg00qf 4586 1 In in IN cord-022526-j9kg00qf 4586 2 adult adult NN cord-022526-j9kg00qf 4586 3 horses horse NNS cord-022526-j9kg00qf 4586 4 , , , cord-022526-j9kg00qf 4586 5 volvulus volvulus NN cord-022526-j9kg00qf 4586 6 frequently frequently RB cord-022526-j9kg00qf 4586 7 occurs occur VBZ cord-022526-j9kg00qf 4586 8 in in IN cord-022526-j9kg00qf 4586 9 association association NN cord-022526-j9kg00qf 4586 10 with with IN cord-022526-j9kg00qf 4586 11 another another DT cord-022526-j9kg00qf 4586 12 disease disease NN cord-022526-j9kg00qf 4586 13 process process NN cord-022526-j9kg00qf 4586 14 , , , cord-022526-j9kg00qf 4586 15 during during IN cord-022526-j9kg00qf 4586 16 which which WDT cord-022526-j9kg00qf 4586 17 small small JJ cord-022526-j9kg00qf 4586 18 intestinal intestinal JJ cord-022526-j9kg00qf 4586 19 obstruction obstruction NN cord-022526-j9kg00qf 4586 20 results result NNS cord-022526-j9kg00qf 4586 21 in in IN cord-022526-j9kg00qf 4586 22 distention distention NN cord-022526-j9kg00qf 4586 23 and and CC cord-022526-j9kg00qf 4586 24 subsequent subsequent JJ cord-022526-j9kg00qf 4586 25 rotation rotation NN cord-022526-j9kg00qf 4586 26 of of IN cord-022526-j9kg00qf 4586 27 the the DT cord-022526-j9kg00qf 4586 28 small small JJ cord-022526-j9kg00qf 4586 29 intestine intestine NN cord-022526-j9kg00qf 4586 30 around around IN cord-022526-j9kg00qf 4586 31 the the DT cord-022526-j9kg00qf 4586 32 root root NN cord-022526-j9kg00qf 4586 33 of of IN cord-022526-j9kg00qf 4586 34 the the DT cord-022526-j9kg00qf 4586 35 mesentery mesentery NN cord-022526-j9kg00qf 4586 36 . . . cord-022526-j9kg00qf 4587 1 Although although IN cord-022526-j9kg00qf 4587 2 any any DT cord-022526-j9kg00qf 4587 3 segment segment NN cord-022526-j9kg00qf 4587 4 of of IN cord-022526-j9kg00qf 4587 5 the the DT cord-022526-j9kg00qf 4587 6 small small JJ cord-022526-j9kg00qf 4587 7 intestine intestine NN cord-022526-j9kg00qf 4587 8 may may MD cord-022526-j9kg00qf 4587 9 be be VB cord-022526-j9kg00qf 4587 10 involved involve VBN cord-022526-j9kg00qf 4587 11 , , , cord-022526-j9kg00qf 4587 12 the the DT cord-022526-j9kg00qf 4587 13 distal distal JJ cord-022526-j9kg00qf 4587 14 jejunum jejunum NNS cord-022526-j9kg00qf 4587 15 and and CC cord-022526-j9kg00qf 4587 16 ileum ileum NN cord-022526-j9kg00qf 4587 17 are be VBP cord-022526-j9kg00qf 4587 18 affected affect VBN cord-022526-j9kg00qf 4587 19 most most RBS cord-022526-j9kg00qf 4587 20 frequently frequently RB cord-022526-j9kg00qf 4587 21 because because IN cord-022526-j9kg00qf 4587 22 of of IN cord-022526-j9kg00qf 4587 23 their -PRON- PRP$ cord-022526-j9kg00qf 4587 24 longer long JJR cord-022526-j9kg00qf 4587 25 mesenteries mesentery NNS cord-022526-j9kg00qf 4587 26 . . . cord-022526-j9kg00qf 4588 1 11 11 CD cord-022526-j9kg00qf 4589 1 One one PRP cord-022526-j9kg00qf 4589 2 makes make VBZ cord-022526-j9kg00qf 4589 3 the the DT cord-022526-j9kg00qf 4589 4 diagnosis diagnosis NN cord-022526-j9kg00qf 4589 5 at at IN cord-022526-j9kg00qf 4589 6 surgery surgery NN cord-022526-j9kg00qf 4589 7 by by IN cord-022526-j9kg00qf 4589 8 palpating palpate VBG cord-022526-j9kg00qf 4589 9 a a DT cord-022526-j9kg00qf 4589 10 twist twist NN cord-022526-j9kg00qf 4589 11 at at IN cord-022526-j9kg00qf 4589 12 the the DT cord-022526-j9kg00qf 4589 13 origin origin NN cord-022526-j9kg00qf 4589 14 of of IN cord-022526-j9kg00qf 4589 15 the the DT cord-022526-j9kg00qf 4589 16 cranial cranial JJ cord-022526-j9kg00qf 4589 17 mesenteric mesenteric JJ cord-022526-j9kg00qf 4589 18 artery artery NN cord-022526-j9kg00qf 4589 19 . . . cord-022526-j9kg00qf 4590 1 Treatment treatment NN cord-022526-j9kg00qf 4590 2 includes include VBZ cord-022526-j9kg00qf 4590 3 resection resection NN cord-022526-j9kg00qf 4590 4 of of IN cord-022526-j9kg00qf 4590 5 devitalized devitalized JJ cord-022526-j9kg00qf 4590 6 bowel bowel NN cord-022526-j9kg00qf 4590 7 , , , cord-022526-j9kg00qf 4590 8 which which WDT cord-022526-j9kg00qf 4590 9 may may MD cord-022526-j9kg00qf 4590 10 not not RB cord-022526-j9kg00qf 4590 11 be be VB cord-022526-j9kg00qf 4590 12 an an DT cord-022526-j9kg00qf 4590 13 option option NN cord-022526-j9kg00qf 4590 14 because because IN cord-022526-j9kg00qf 4590 15 of of IN cord-022526-j9kg00qf 4590 16 the the DT cord-022526-j9kg00qf 4590 17 extent extent NN cord-022526-j9kg00qf 4590 18 of of IN cord-022526-j9kg00qf 4590 19 small small JJ cord-022526-j9kg00qf 4590 20 intestinal intestinal JJ cord-022526-j9kg00qf 4590 21 involvement involvement NN cord-022526-j9kg00qf 4590 22 ( ( -LRB- cord-022526-j9kg00qf 4590 23 similar similar JJ cord-022526-j9kg00qf 4590 24 to to IN cord-022526-j9kg00qf 4590 25 large large JJ cord-022526-j9kg00qf 4590 26 colon colon NN cord-022526-j9kg00qf 4590 27 volvulus volvulus NN cord-022526-j9kg00qf 4590 28 ) ) -RRB- cord-022526-j9kg00qf 4590 29 . . . cord-022526-j9kg00qf 4591 1 Prognosis prognosis NN cord-022526-j9kg00qf 4591 2 is be VBZ cord-022526-j9kg00qf 4591 3 based base VBN cord-022526-j9kg00qf 4591 4 on on IN cord-022526-j9kg00qf 4591 5 the the DT cord-022526-j9kg00qf 4591 6 extent extent NN cord-022526-j9kg00qf 4591 7 of of IN cord-022526-j9kg00qf 4591 8 small small JJ cord-022526-j9kg00qf 4591 9 intestine intestine NN cord-022526-j9kg00qf 4591 10 involved involve VBN cord-022526-j9kg00qf 4591 11 and and CC cord-022526-j9kg00qf 4591 12 its -PRON- PRP$ cord-022526-j9kg00qf 4591 13 appearance appearance NN cord-022526-j9kg00qf 4591 14 following follow VBG cord-022526-j9kg00qf 4591 15 surgical surgical JJ cord-022526-j9kg00qf 4591 16 correction correction NN cord-022526-j9kg00qf 4591 17 of of IN cord-022526-j9kg00qf 4591 18 the the DT cord-022526-j9kg00qf 4591 19 lesion lesion NN cord-022526-j9kg00qf 4591 20 . . . cord-022526-j9kg00qf 4592 1 In in IN cord-022526-j9kg00qf 4592 2 general general JJ cord-022526-j9kg00qf 4592 3 , , , cord-022526-j9kg00qf 4592 4 horses horse NNS cord-022526-j9kg00qf 4592 5 with with IN cord-022526-j9kg00qf 4592 6 greater great JJR cord-022526-j9kg00qf 4592 7 than than IN cord-022526-j9kg00qf 4592 8 50 50 CD cord-022526-j9kg00qf 4592 9 % % NN cord-022526-j9kg00qf 4592 10 of of IN cord-022526-j9kg00qf 4592 11 the the DT cord-022526-j9kg00qf 4592 12 small small JJ cord-022526-j9kg00qf 4592 13 intestine intestine NN cord-022526-j9kg00qf 4592 14 devitalized devitalize VBN cord-022526-j9kg00qf 4592 15 are be VBP cord-022526-j9kg00qf 4592 16 considered consider VBN cord-022526-j9kg00qf 4592 17 to to TO cord-022526-j9kg00qf 4592 18 have have VB cord-022526-j9kg00qf 4592 19 a a DT cord-022526-j9kg00qf 4592 20 grave grave JJ cord-022526-j9kg00qf 4592 21 prognosis prognosis NN cord-022526-j9kg00qf 4592 22 . . . cord-022526-j9kg00qf 4593 1 33 33 CD cord-022526-j9kg00qf 4593 2 A a DT cord-022526-j9kg00qf 4593 3 number number NN cord-022526-j9kg00qf 4593 4 of of IN cord-022526-j9kg00qf 4593 5 structures structure NNS cord-022526-j9kg00qf 4593 6 , , , cord-022526-j9kg00qf 4593 7 when when WRB cord-022526-j9kg00qf 4593 8 torn tear VBN cord-022526-j9kg00qf 4593 9 , , , cord-022526-j9kg00qf 4593 10 may may MD cord-022526-j9kg00qf 4593 11 incarcerate incarcerate VB cord-022526-j9kg00qf 4593 12 a a DT cord-022526-j9kg00qf 4593 13 segment segment NN cord-022526-j9kg00qf 4593 14 of of IN cord-022526-j9kg00qf 4593 15 intestine intestine NN cord-022526-j9kg00qf 4593 16 ( ( -LRB- cord-022526-j9kg00qf 4593 17 typically typically RB cord-022526-j9kg00qf 4593 18 the the DT cord-022526-j9kg00qf 4593 19 small small JJ cord-022526-j9kg00qf 4593 20 intestine intestine NN cord-022526-j9kg00qf 4593 21 ) ) -RRB- cord-022526-j9kg00qf 4593 22 , , , cord-022526-j9kg00qf 4593 23 including include VBG cord-022526-j9kg00qf 4593 24 intestinal intestinal JJ cord-022526-j9kg00qf 4593 25 mesentery mesentery NN cord-022526-j9kg00qf 4593 26 , , , cord-022526-j9kg00qf 4593 27 20 20 CD cord-022526-j9kg00qf 4593 28 the the DT cord-022526-j9kg00qf 4593 29 gastrosplenic gastrosplenic NNP cord-022526-j9kg00qf 4593 30 ligament ligament NN cord-022526-j9kg00qf 4593 31 , , , cord-022526-j9kg00qf 4593 32 34 34 CD cord-022526-j9kg00qf 4593 33 the the DT cord-022526-j9kg00qf 4593 34 broad broad JJ cord-022526-j9kg00qf 4593 35 ligament ligament NN cord-022526-j9kg00qf 4593 36 , , , cord-022526-j9kg00qf 4593 37 35 35 CD cord-022526-j9kg00qf 4593 38 and and CC cord-022526-j9kg00qf 4593 39 the the DT cord-022526-j9kg00qf 4593 40 cecocolic cecocolic JJ cord-022526-j9kg00qf 4593 41 ligament ligament NN cord-022526-j9kg00qf 4593 42 . . . cord-022526-j9kg00qf 4594 1 36 36 CD cord-022526-j9kg00qf 4594 2 Horses horse NNS cord-022526-j9kg00qf 4594 3 with with IN cord-022526-j9kg00qf 4594 4 such such JJ cord-022526-j9kg00qf 4594 5 incarcerations incarceration NNS cord-022526-j9kg00qf 4594 6 have have VBP cord-022526-j9kg00qf 4594 7 signs sign NNS cord-022526-j9kg00qf 4594 8 typical typical JJ cord-022526-j9kg00qf 4594 9 of of IN cord-022526-j9kg00qf 4594 10 a a DT cord-022526-j9kg00qf 4594 11 horse horse NN cord-022526-j9kg00qf 4594 12 with with IN cord-022526-j9kg00qf 4594 13 strangulating strangulate VBG cord-022526-j9kg00qf 4594 14 small small JJ cord-022526-j9kg00qf 4594 15 intestine intestine NN cord-022526-j9kg00qf 4594 16 , , , cord-022526-j9kg00qf 4594 17 including include VBG cord-022526-j9kg00qf 4594 18 moderate moderate JJ cord-022526-j9kg00qf 4594 19 to to IN cord-022526-j9kg00qf 4594 20 severe severe JJ cord-022526-j9kg00qf 4594 21 signs sign NNS cord-022526-j9kg00qf 4594 22 of of IN cord-022526-j9kg00qf 4594 23 abdominal abdominal JJ cord-022526-j9kg00qf 4594 24 pain pain NN cord-022526-j9kg00qf 4594 25 , , , cord-022526-j9kg00qf 4594 26 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4594 27 , , , cord-022526-j9kg00qf 4594 28 absent absent JJ cord-022526-j9kg00qf 4594 29 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4594 30 sounds sound NNS cord-022526-j9kg00qf 4594 31 , , , cord-022526-j9kg00qf 4594 32 distended distend VBD cord-022526-j9kg00qf 4594 33 small small JJ cord-022526-j9kg00qf 4594 34 intestine intestine NN cord-022526-j9kg00qf 4594 35 on on IN cord-022526-j9kg00qf 4594 36 per per IN cord-022526-j9kg00qf 4594 37 rectal rectal JJ cord-022526-j9kg00qf 4594 38 palpation palpation NN cord-022526-j9kg00qf 4594 39 , , , cord-022526-j9kg00qf 4594 40 nasogastric nasogastric NN cord-022526-j9kg00qf 4594 41 reflux reflux NN cord-022526-j9kg00qf 4594 42 , , , cord-022526-j9kg00qf 4594 43 and and CC cord-022526-j9kg00qf 4594 44 serosanguinous serosanguinous JJ cord-022526-j9kg00qf 4594 45 abdominal abdominal JJ cord-022526-j9kg00qf 4594 46 fluid fluid NN cord-022526-j9kg00qf 4594 47 . . . cord-022526-j9kg00qf 4595 1 However however RB cord-022526-j9kg00qf 4595 2 , , , cord-022526-j9kg00qf 4595 3 the the DT cord-022526-j9kg00qf 4595 4 prognosis prognosis NN cord-022526-j9kg00qf 4595 5 for for IN cord-022526-j9kg00qf 4595 6 many many JJ cord-022526-j9kg00qf 4595 7 of of IN cord-022526-j9kg00qf 4595 8 these these DT cord-022526-j9kg00qf 4595 9 horses horse NNS cord-022526-j9kg00qf 4595 10 appears appear VBZ cord-022526-j9kg00qf 4595 11 to to TO cord-022526-j9kg00qf 4595 12 be be VB cord-022526-j9kg00qf 4595 13 lower low JJR cord-022526-j9kg00qf 4595 14 than than IN cord-022526-j9kg00qf 4595 15 for for IN cord-022526-j9kg00qf 4595 16 horses horse NNS cord-022526-j9kg00qf 4595 17 with with IN cord-022526-j9kg00qf 4595 18 other other JJ cord-022526-j9kg00qf 4595 19 types type NNS cord-022526-j9kg00qf 4595 20 of of IN cord-022526-j9kg00qf 4595 21 small small JJ cord-022526-j9kg00qf 4595 22 intestinal intestinal JJ cord-022526-j9kg00qf 4595 23 strangulations strangulation NNS cord-022526-j9kg00qf 4595 24 . . . cord-022526-j9kg00qf 4596 1 For for IN cord-022526-j9kg00qf 4596 2 example example NN cord-022526-j9kg00qf 4596 3 , , , cord-022526-j9kg00qf 4596 4 in in IN cord-022526-j9kg00qf 4596 5 horses horse NNS cord-022526-j9kg00qf 4596 6 with with IN cord-022526-j9kg00qf 4596 7 small small JJ cord-022526-j9kg00qf 4596 8 intestine intestine NN cord-022526-j9kg00qf 4596 9 entrapped entrap VBN cord-022526-j9kg00qf 4596 10 in in IN cord-022526-j9kg00qf 4596 11 a a DT cord-022526-j9kg00qf 4596 12 mesenteric mesenteric JJ cord-022526-j9kg00qf 4596 13 rent rent NN cord-022526-j9kg00qf 4596 14 , , , cord-022526-j9kg00qf 4596 15 only only RB cord-022526-j9kg00qf 4596 16 7 7 CD cord-022526-j9kg00qf 4596 17 of of IN cord-022526-j9kg00qf 4596 18 15 15 CD cord-022526-j9kg00qf 4596 19 horses horse NNS cord-022526-j9kg00qf 4596 20 were be VBD cord-022526-j9kg00qf 4596 21 discharged discharge VBN cord-022526-j9kg00qf 4596 22 from from IN cord-022526-j9kg00qf 4596 23 the the DT cord-022526-j9kg00qf 4596 24 hospital hospital NN cord-022526-j9kg00qf 4596 25 , , , cord-022526-j9kg00qf 4596 26 and and CC cord-022526-j9kg00qf 4596 27 only only RB cord-022526-j9kg00qf 4596 28 2 2 CD cord-022526-j9kg00qf 4596 29 of of IN cord-022526-j9kg00qf 4596 30 5 5 CD cord-022526-j9kg00qf 4596 31 horses horse NNS cord-022526-j9kg00qf 4596 32 for for IN cord-022526-j9kg00qf 4596 33 which which WDT cord-022526-j9kg00qf 4596 34 follow follow NN cord-022526-j9kg00qf 4596 35 - - HYPH cord-022526-j9kg00qf 4596 36 up up RP cord-022526-j9kg00qf 4596 37 information information NN cord-022526-j9kg00qf 4596 38 was be VBD cord-022526-j9kg00qf 4596 39 available available JJ cord-022526-j9kg00qf 4596 40 survived survive VBN cord-022526-j9kg00qf 4596 41 long long JJ cord-022526-j9kg00qf 4596 42 term term NN cord-022526-j9kg00qf 4596 43 ( ( -LRB- cord-022526-j9kg00qf 4596 44 > > NFP cord-022526-j9kg00qf 4596 45 5 5 CD cord-022526-j9kg00qf 4596 46 months month NNS cord-022526-j9kg00qf 4596 47 ) ) -RRB- cord-022526-j9kg00qf 4596 48 . . . cord-022526-j9kg00qf 4597 1 20 20 CD cord-022526-j9kg00qf 4597 2 Poor poor JJ cord-022526-j9kg00qf 4597 3 outcome outcome NN cord-022526-j9kg00qf 4597 4 may may MD cord-022526-j9kg00qf 4597 5 result result VB cord-022526-j9kg00qf 4597 6 from from IN cord-022526-j9kg00qf 4597 7 the the DT cord-022526-j9kg00qf 4597 8 difficulty difficulty NN cord-022526-j9kg00qf 4597 9 in in IN cord-022526-j9kg00qf 4597 10 unentrapping unentrappe VBG cord-022526-j9kg00qf 4597 11 incarcerated incarcerate VBN cord-022526-j9kg00qf 4597 12 intestine intestine NN cord-022526-j9kg00qf 4597 13 , , , cord-022526-j9kg00qf 4597 14 the the DT cord-022526-j9kg00qf 4597 15 degree degree NN cord-022526-j9kg00qf 4597 16 of of IN cord-022526-j9kg00qf 4597 17 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4597 18 , , , cord-022526-j9kg00qf 4597 19 and and CC cord-022526-j9kg00qf 4597 20 the the DT cord-022526-j9kg00qf 4597 21 length length NN cord-022526-j9kg00qf 4597 22 of of IN cord-022526-j9kg00qf 4597 23 intestine intestine NN cord-022526-j9kg00qf 4597 24 affected affect VBN cord-022526-j9kg00qf 4597 25 . . . cord-022526-j9kg00qf 4598 1 Inguinal inguinal JJ cord-022526-j9kg00qf 4598 2 herniae herniae NN cord-022526-j9kg00qf 4598 3 are be VBP cord-022526-j9kg00qf 4598 4 more more RBR cord-022526-j9kg00qf 4598 5 common common JJ cord-022526-j9kg00qf 4598 6 in in IN cord-022526-j9kg00qf 4598 7 Standardbred Standardbred NNP cord-022526-j9kg00qf 4598 8 and and CC cord-022526-j9kg00qf 4598 9 Tennessee Tennessee NNP cord-022526-j9kg00qf 4598 10 Walking walk VBG cord-022526-j9kg00qf 4598 11 horses horse NNS cord-022526-j9kg00qf 4598 12 that that WDT cord-022526-j9kg00qf 4598 13 tend tend VBP cord-022526-j9kg00qf 4598 14 to to TO cord-022526-j9kg00qf 4598 15 have have VB cord-022526-j9kg00qf 4598 16 congenitally congenitally RB cord-022526-j9kg00qf 4598 17 large large JJ cord-022526-j9kg00qf 4598 18 inguinal inguinal JJ cord-022526-j9kg00qf 4598 19 canals canal NNS cord-022526-j9kg00qf 4598 20 . . . cord-022526-j9kg00qf 4599 1 11 11 CD cord-022526-j9kg00qf 4599 2 Inguinal inguinal JJ cord-022526-j9kg00qf 4599 3 herniae herniae NN cord-022526-j9kg00qf 4599 4 also also RB cord-022526-j9kg00qf 4599 5 may may MD cord-022526-j9kg00qf 4599 6 occur occur VB cord-022526-j9kg00qf 4599 7 in in IN cord-022526-j9kg00qf 4599 8 neonatal neonatal JJ cord-022526-j9kg00qf 4599 9 foals foal NNS cord-022526-j9kg00qf 4599 10 but but CC cord-022526-j9kg00qf 4599 11 differ differ VBP cord-022526-j9kg00qf 4599 12 from from IN cord-022526-j9kg00qf 4599 13 herniae herniae NN cord-022526-j9kg00qf 4599 14 in in IN cord-022526-j9kg00qf 4599 15 mature mature JJ cord-022526-j9kg00qf 4599 16 horses horse NNS cord-022526-j9kg00qf 4599 17 in in IN cord-022526-j9kg00qf 4599 18 that that IN cord-022526-j9kg00qf 4599 19 they -PRON- PRP cord-022526-j9kg00qf 4599 20 are be VBP cord-022526-j9kg00qf 4599 21 typically typically RB cord-022526-j9kg00qf 4599 22 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 4599 23 . . . cord-022526-j9kg00qf 4600 1 The the DT cord-022526-j9kg00qf 4600 2 nature nature NN cord-022526-j9kg00qf 4600 3 of of IN cord-022526-j9kg00qf 4600 4 the the DT cord-022526-j9kg00qf 4600 5 hernia hernia NN cord-022526-j9kg00qf 4600 6 ( ( -LRB- cord-022526-j9kg00qf 4600 7 direct direct JJ cord-022526-j9kg00qf 4600 8 versus versus IN cord-022526-j9kg00qf 4600 9 indirect indirect JJ cord-022526-j9kg00qf 4600 10 ) ) -RRB- cord-022526-j9kg00qf 4600 11 is be VBZ cord-022526-j9kg00qf 4600 12 based base VBN cord-022526-j9kg00qf 4600 13 on on IN cord-022526-j9kg00qf 4600 14 the the DT cord-022526-j9kg00qf 4600 15 integrity integrity NN cord-022526-j9kg00qf 4600 16 of of IN cord-022526-j9kg00qf 4600 17 the the DT cord-022526-j9kg00qf 4600 18 parietal parietal JJ cord-022526-j9kg00qf 4600 19 vaginal vaginal JJ cord-022526-j9kg00qf 4600 20 tunic tunic NN cord-022526-j9kg00qf 4600 21 . . . cord-022526-j9kg00qf 4601 1 In in IN cord-022526-j9kg00qf 4601 2 horses horse NNS cord-022526-j9kg00qf 4601 3 in in IN cord-022526-j9kg00qf 4601 4 which which WDT cord-022526-j9kg00qf 4601 5 the the DT cord-022526-j9kg00qf 4601 6 bowel bowel NN cord-022526-j9kg00qf 4601 7 remains remain VBZ cord-022526-j9kg00qf 4601 8 within within IN cord-022526-j9kg00qf 4601 9 the the DT cord-022526-j9kg00qf 4601 10 parietal parietal JJ cord-022526-j9kg00qf 4601 11 vaginal vaginal JJ cord-022526-j9kg00qf 4601 12 tunic tunic NN cord-022526-j9kg00qf 4601 13 , , , cord-022526-j9kg00qf 4601 14 the the DT cord-022526-j9kg00qf 4601 15 hernia hernia NN cord-022526-j9kg00qf 4601 16 is be VBZ cord-022526-j9kg00qf 4601 17 referred refer VBN cord-022526-j9kg00qf 4601 18 to to IN cord-022526-j9kg00qf 4601 19 as as RB cord-022526-j9kg00qf 4601 20 indirect indirect JJ cord-022526-j9kg00qf 4601 21 , , , cord-022526-j9kg00qf 4601 22 because because IN cord-022526-j9kg00qf 4601 23 strictly strictly RB cord-022526-j9kg00qf 4601 24 speaking speak VBG cord-022526-j9kg00qf 4601 25 the the DT cord-022526-j9kg00qf 4601 26 bowel bowel NN cord-022526-j9kg00qf 4601 27 remains remain VBZ cord-022526-j9kg00qf 4601 28 within within IN cord-022526-j9kg00qf 4601 29 the the DT cord-022526-j9kg00qf 4601 30 peritoneal peritoneal JJ cord-022526-j9kg00qf 4601 31 cavity cavity NN cord-022526-j9kg00qf 4601 32 . . . cord-022526-j9kg00qf 4602 1 Direct direct JJ cord-022526-j9kg00qf 4602 2 herniae herniae NN cord-022526-j9kg00qf 4602 3 are be VBP cord-022526-j9kg00qf 4602 4 those those DT cord-022526-j9kg00qf 4602 5 in in IN cord-022526-j9kg00qf 4602 6 which which WDT cord-022526-j9kg00qf 4602 7 strangulated strangulated JJ cord-022526-j9kg00qf 4602 8 bowel bowel NN cord-022526-j9kg00qf 4602 9 ruptures rupture NNS cord-022526-j9kg00qf 4602 10 through through IN cord-022526-j9kg00qf 4602 11 the the DT cord-022526-j9kg00qf 4602 12 parietal parietal JJ cord-022526-j9kg00qf 4602 13 vaginal vaginal JJ cord-022526-j9kg00qf 4602 14 tunic tunic NN cord-022526-j9kg00qf 4602 15 and and CC cord-022526-j9kg00qf 4602 16 occupies occupy VBZ cord-022526-j9kg00qf 4602 17 a a DT cord-022526-j9kg00qf 4602 18 subcutaneous subcutaneous JJ cord-022526-j9kg00qf 4602 19 location location NN cord-022526-j9kg00qf 4602 20 . . . cord-022526-j9kg00qf 4603 1 These these DT cord-022526-j9kg00qf 4603 2 direct direct JJ cord-022526-j9kg00qf 4603 3 herniae herniae NN cord-022526-j9kg00qf 4603 4 most most RBS cord-022526-j9kg00qf 4603 5 commonly commonly RB cord-022526-j9kg00qf 4603 6 occur occur VBP cord-022526-j9kg00qf 4603 7 in in IN cord-022526-j9kg00qf 4603 8 foals foal NNS cord-022526-j9kg00qf 4603 9 and and CC cord-022526-j9kg00qf 4603 10 should should MD cord-022526-j9kg00qf 4603 11 be be VB cord-022526-j9kg00qf 4603 12 suspected suspect VBN cord-022526-j9kg00qf 4603 13 when when WRB cord-022526-j9kg00qf 4603 14 a a DT cord-022526-j9kg00qf 4603 15 congenital congenital JJ cord-022526-j9kg00qf 4603 16 inguinal inguinal JJ cord-022526-j9kg00qf 4603 17 hernia hernia NN cord-022526-j9kg00qf 4603 18 is be VBZ cord-022526-j9kg00qf 4603 19 associated associate VBN cord-022526-j9kg00qf 4603 20 with with IN cord-022526-j9kg00qf 4603 21 colic colic NN cord-022526-j9kg00qf 4603 22 , , , cord-022526-j9kg00qf 4603 23 swelling swell VBG cord-022526-j9kg00qf 4603 24 that that WDT cord-022526-j9kg00qf 4603 25 extends extend VBZ cord-022526-j9kg00qf 4603 26 from from IN cord-022526-j9kg00qf 4603 27 the the DT cord-022526-j9kg00qf 4603 28 inguinal inguinal JJ cord-022526-j9kg00qf 4603 29 region region NN cord-022526-j9kg00qf 4603 30 or or CC cord-022526-j9kg00qf 4603 31 the the DT cord-022526-j9kg00qf 4603 32 prepuce prepuce NN cord-022526-j9kg00qf 4603 33 , , , cord-022526-j9kg00qf 4603 34 and and CC cord-022526-j9kg00qf 4603 35 intestine intestine NN cord-022526-j9kg00qf 4603 36 that that WDT cord-022526-j9kg00qf 4603 37 may may MD cord-022526-j9kg00qf 4603 38 be be VB cord-022526-j9kg00qf 4603 39 palpated palpate VBN cord-022526-j9kg00qf 4603 40 subcutaneously subcutaneously RB cord-022526-j9kg00qf 4603 41 . . . cord-022526-j9kg00qf 4604 1 37 37 CD cord-022526-j9kg00qf 4604 2 , , , cord-022526-j9kg00qf 4604 3 38 38 CD cord-022526-j9kg00qf 4605 1 Although although IN cord-022526-j9kg00qf 4605 2 most most JJS cord-022526-j9kg00qf 4605 3 congenital congenital JJ cord-022526-j9kg00qf 4605 4 indirect indirect JJ cord-022526-j9kg00qf 4605 5 inguinal inguinal JJ cord-022526-j9kg00qf 4605 6 herniae herniae NN cord-022526-j9kg00qf 4605 7 resolve resolve VB cord-022526-j9kg00qf 4605 8 with with IN cord-022526-j9kg00qf 4605 9 repeated repeat VBN cord-022526-j9kg00qf 4605 10 manual manual JJ cord-022526-j9kg00qf 4605 11 reduction reduction NN cord-022526-j9kg00qf 4605 12 or or CC cord-022526-j9kg00qf 4605 13 application application NN cord-022526-j9kg00qf 4605 14 of of IN cord-022526-j9kg00qf 4605 15 a a DT cord-022526-j9kg00qf 4605 16 diaper diaper NN cord-022526-j9kg00qf 4605 17 , , , cord-022526-j9kg00qf 4605 18 surgical surgical JJ cord-022526-j9kg00qf 4605 19 intervention intervention NN cord-022526-j9kg00qf 4605 20 is be VBZ cord-022526-j9kg00qf 4605 21 recommended recommend VBN cord-022526-j9kg00qf 4605 22 for for IN cord-022526-j9kg00qf 4605 23 congenial congenial JJ cord-022526-j9kg00qf 4605 24 direct direct JJ cord-022526-j9kg00qf 4605 25 herniae herniae NN cord-022526-j9kg00qf 4605 26 . . . cord-022526-j9kg00qf 4606 1 37 37 CD cord-022526-j9kg00qf 4606 2 Historical historical JJ cord-022526-j9kg00qf 4606 3 findings finding NNS cord-022526-j9kg00qf 4606 4 in in IN cord-022526-j9kg00qf 4606 5 horses horse NNS cord-022526-j9kg00qf 4606 6 with with IN cord-022526-j9kg00qf 4606 7 strangulating strangulate VBG cord-022526-j9kg00qf 4606 8 inguinal inguinal JJ cord-022526-j9kg00qf 4606 9 herniae herniae NN cord-022526-j9kg00qf 4606 10 include include VBP cord-022526-j9kg00qf 4606 11 acute acute JJ cord-022526-j9kg00qf 4606 12 onset onset NN cord-022526-j9kg00qf 4606 13 of of IN cord-022526-j9kg00qf 4606 14 colic colic NN cord-022526-j9kg00qf 4606 15 in in IN cord-022526-j9kg00qf 4606 16 a a DT cord-022526-j9kg00qf 4606 17 stallion stallion NN cord-022526-j9kg00qf 4606 18 that that WDT cord-022526-j9kg00qf 4606 19 recently recently RB cord-022526-j9kg00qf 4606 20 had have VBD cord-022526-j9kg00qf 4606 21 been be VBN cord-022526-j9kg00qf 4606 22 used use VBN cord-022526-j9kg00qf 4606 23 for for IN cord-022526-j9kg00qf 4606 24 breeding breed VBG cord-022526-j9kg00qf 4606 25 . . . cord-022526-j9kg00qf 4607 1 A a DT cord-022526-j9kg00qf 4607 2 cardinal cardinal JJ cord-022526-j9kg00qf 4607 3 sign sign NN cord-022526-j9kg00qf 4607 4 of of IN cord-022526-j9kg00qf 4607 5 inguinal inguinal JJ cord-022526-j9kg00qf 4607 6 herniation herniation NN cord-022526-j9kg00qf 4607 7 is be VBZ cord-022526-j9kg00qf 4607 8 a a DT cord-022526-j9kg00qf 4607 9 cool cool JJ cord-022526-j9kg00qf 4607 10 , , , cord-022526-j9kg00qf 4607 11 enlarged enlarged JJ cord-022526-j9kg00qf 4607 12 testicle testicle NN cord-022526-j9kg00qf 4607 13 on on IN cord-022526-j9kg00qf 4607 14 one one CD cord-022526-j9kg00qf 4607 15 side side NN cord-022526-j9kg00qf 4607 16 of of IN cord-022526-j9kg00qf 4607 17 the the DT cord-022526-j9kg00qf 4607 18 scrotum scrotum NN cord-022526-j9kg00qf 4608 1 ( ( -LRB- cord-022526-j9kg00qf 4608 2 Figure figure NN cord-022526-j9kg00qf 4608 3 13 13 CD cord-022526-j9kg00qf 4608 4 .14 .14 CD cord-022526-j9kg00qf 4608 5 - - SYM cord-022526-j9kg00qf 4608 6 2 2 CD cord-022526-j9kg00qf 4608 7 ) ) -RRB- cord-022526-j9kg00qf 4608 8 . . . cord-022526-j9kg00qf 4609 1 39 39 CD cord-022526-j9kg00qf 4609 2 , , , cord-022526-j9kg00qf 4609 3 40 40 CD cord-022526-j9kg00qf 4610 1 However however RB cord-022526-j9kg00qf 4610 2 , , , cord-022526-j9kg00qf 4610 3 inguinal inguinal JJ cord-022526-j9kg00qf 4610 4 herniae herniae NN cord-022526-j9kg00qf 4610 5 also also RB cord-022526-j9kg00qf 4610 6 have have VBP cord-022526-j9kg00qf 4610 7 been be VBN cord-022526-j9kg00qf 4610 8 reported report VBN cord-022526-j9kg00qf 4610 9 in in IN cord-022526-j9kg00qf 4610 10 geldings gelding NNS cord-022526-j9kg00qf 4610 11 . . . cord-022526-j9kg00qf 4611 1 41 41 CD cord-022526-j9kg00qf 4611 2 One one CD cord-022526-j9kg00qf 4611 3 also also RB cord-022526-j9kg00qf 4611 4 can can MD cord-022526-j9kg00qf 4611 5 detect detect VB cord-022526-j9kg00qf 4611 6 inguinal inguinal JJ cord-022526-j9kg00qf 4611 7 herniae herniae NN cord-022526-j9kg00qf 4611 8 on on IN cord-022526-j9kg00qf 4611 9 rectal rectal JJ cord-022526-j9kg00qf 4611 10 palpation palpation NN cord-022526-j9kg00qf 4611 11 , , , cord-022526-j9kg00qf 4611 12 and and CC cord-022526-j9kg00qf 4611 13 one one PRP cord-022526-j9kg00qf 4611 14 can can MD cord-022526-j9kg00qf 4611 15 use use VB cord-022526-j9kg00qf 4611 16 manipulation manipulation NN cord-022526-j9kg00qf 4611 17 of of IN cord-022526-j9kg00qf 4611 18 herniated herniated JJ cord-022526-j9kg00qf 4611 19 bowel bowel NN cord-022526-j9kg00qf 4611 20 per per IN cord-022526-j9kg00qf 4611 21 rectum rectum NN cord-022526-j9kg00qf 4611 22 to to TO cord-022526-j9kg00qf 4611 23 reduce reduce VB cord-022526-j9kg00qf 4611 24 a a DT cord-022526-j9kg00qf 4611 25 hernia hernia NN cord-022526-j9kg00qf 4611 26 , , , cord-022526-j9kg00qf 4611 27 but but CC cord-022526-j9kg00qf 4611 28 this this DT cord-022526-j9kg00qf 4611 29 is be VBZ cord-022526-j9kg00qf 4611 30 generally generally RB cord-022526-j9kg00qf 4611 31 not not RB cord-022526-j9kg00qf 4611 32 recommended recommend VBN cord-022526-j9kg00qf 4611 33 because because IN cord-022526-j9kg00qf 4611 34 of of IN cord-022526-j9kg00qf 4611 35 the the DT cord-022526-j9kg00qf 4611 36 risk risk NN cord-022526-j9kg00qf 4611 37 of of IN cord-022526-j9kg00qf 4611 38 rectal rectal JJ cord-022526-j9kg00qf 4611 39 tears tear NNS cord-022526-j9kg00qf 4611 40 . . . cord-022526-j9kg00qf 4612 1 In in IN cord-022526-j9kg00qf 4612 2 many many JJ cord-022526-j9kg00qf 4612 3 cases case NNS cord-022526-j9kg00qf 4612 4 , , , cord-022526-j9kg00qf 4612 5 the the DT cord-022526-j9kg00qf 4612 6 short short JJ cord-022526-j9kg00qf 4612 7 segment segment NN cord-022526-j9kg00qf 4612 8 of of IN cord-022526-j9kg00qf 4612 9 herniated herniated JJ cord-022526-j9kg00qf 4612 10 intestine intestine NN cord-022526-j9kg00qf 4612 11 greatly greatly RB cord-022526-j9kg00qf 4612 12 improves improve VBZ cord-022526-j9kg00qf 4612 13 in in IN cord-022526-j9kg00qf 4612 14 appearance appearance NN cord-022526-j9kg00qf 4612 15 after after IN cord-022526-j9kg00qf 4612 16 reduction reduction NN cord-022526-j9kg00qf 4612 17 and and CC cord-022526-j9kg00qf 4612 18 in in IN cord-022526-j9kg00qf 4612 19 some some DT cord-022526-j9kg00qf 4612 20 cases case NNS cord-022526-j9kg00qf 4612 21 can can MD cord-022526-j9kg00qf 4612 22 be be VB cord-022526-j9kg00qf 4612 23 left leave VBN cord-022526-j9kg00qf 4612 24 unresected unresected JJ cord-022526-j9kg00qf 4612 25 . . . cord-022526-j9kg00qf 4613 1 The the DT cord-022526-j9kg00qf 4613 2 affected affected JJ cord-022526-j9kg00qf 4613 3 testicle testicle NN cord-022526-j9kg00qf 4613 4 will will MD cord-022526-j9kg00qf 4613 5 be be VB cord-022526-j9kg00qf 4613 6 congested congest VBN cord-022526-j9kg00qf 4613 7 because because IN cord-022526-j9kg00qf 4613 8 of of IN cord-022526-j9kg00qf 4613 9 vascular vascular JJ cord-022526-j9kg00qf 4613 10 compromise compromise NN cord-022526-j9kg00qf 4613 11 within within IN cord-022526-j9kg00qf 4613 12 the the DT cord-022526-j9kg00qf 4613 13 spermatic spermatic JJ cord-022526-j9kg00qf 4613 14 cord cord NN cord-022526-j9kg00qf 4613 15 , , , cord-022526-j9kg00qf 4613 16 and and CC cord-022526-j9kg00qf 4613 17 although although IN cord-022526-j9kg00qf 4613 18 the the DT cord-022526-j9kg00qf 4613 19 testicle testicle NN cord-022526-j9kg00qf 4613 20 may may MD cord-022526-j9kg00qf 4613 21 remain remain VB cord-022526-j9kg00qf 4613 22 viable viable JJ cord-022526-j9kg00qf 4613 23 , , , cord-022526-j9kg00qf 4613 24 resection resection NN cord-022526-j9kg00qf 4613 25 generally generally RB cord-022526-j9kg00qf 4613 26 is be VBZ cord-022526-j9kg00qf 4613 27 recommended recommend VBN cord-022526-j9kg00qf 4613 28 . . . cord-022526-j9kg00qf 4614 1 42 42 CD cord-022526-j9kg00qf 4615 1 The the DT cord-022526-j9kg00qf 4615 2 prognosis prognosis NN cord-022526-j9kg00qf 4615 3 in in IN cord-022526-j9kg00qf 4615 4 adult adult NN cord-022526-j9kg00qf 4615 5 horses horse NNS cord-022526-j9kg00qf 4615 6 is be VBZ cord-022526-j9kg00qf 4615 7 good good JJ cord-022526-j9kg00qf 4615 8 , , , cord-022526-j9kg00qf 4615 9 with with IN cord-022526-j9kg00qf 4615 10 up up IN cord-022526-j9kg00qf 4615 11 to to TO cord-022526-j9kg00qf 4615 12 75 75 CD cord-022526-j9kg00qf 4615 13 % % NN cord-022526-j9kg00qf 4615 14 of of IN cord-022526-j9kg00qf 4615 15 horses horse NNS cord-022526-j9kg00qf 4615 16 surviving survive VBG cord-022526-j9kg00qf 4615 17 to to IN cord-022526-j9kg00qf 4615 18 6 6 CD cord-022526-j9kg00qf 4615 19 months month NNS cord-022526-j9kg00qf 4615 20 . . . cord-022526-j9kg00qf 4616 1 40 40 CD cord-022526-j9kg00qf 4616 2 Horses horse NNS cord-022526-j9kg00qf 4616 3 that that WDT cord-022526-j9kg00qf 4616 4 have have VBP cord-022526-j9kg00qf 4616 5 been be VBN cord-022526-j9kg00qf 4616 6 treated treat VBN cord-022526-j9kg00qf 4616 7 for for IN cord-022526-j9kg00qf 4616 8 inguinal inguinal JJ cord-022526-j9kg00qf 4616 9 herniae herniae NN cord-022526-j9kg00qf 4616 10 may may MD cord-022526-j9kg00qf 4616 11 be be VB cord-022526-j9kg00qf 4616 12 used use VBN cord-022526-j9kg00qf 4616 13 for for IN cord-022526-j9kg00qf 4616 14 breeding breed VBG cord-022526-j9kg00qf 4616 15 . . . cord-022526-j9kg00qf 4617 1 In in IN cord-022526-j9kg00qf 4617 2 these these DT cord-022526-j9kg00qf 4617 3 horses horse NNS cord-022526-j9kg00qf 4617 4 , , , cord-022526-j9kg00qf 4617 5 the the DT cord-022526-j9kg00qf 4617 6 remaining remain VBG cord-022526-j9kg00qf 4617 7 testicle testicle NN cord-022526-j9kg00qf 4617 8 will will MD cord-022526-j9kg00qf 4617 9 have have VB cord-022526-j9kg00qf 4617 10 increased increase VBN cord-022526-j9kg00qf 4617 11 sperm sperm NN cord-022526-j9kg00qf 4617 12 production production NN cord-022526-j9kg00qf 4617 13 , , , cord-022526-j9kg00qf 4617 14 although although IN cord-022526-j9kg00qf 4617 15 an an DT cord-022526-j9kg00qf 4617 16 increased increase VBN cord-022526-j9kg00qf 4617 17 number number NN cord-022526-j9kg00qf 4617 18 of of IN cord-022526-j9kg00qf 4617 19 sperm sperm NN cord-022526-j9kg00qf 4617 20 abnormalities abnormality NNS cord-022526-j9kg00qf 4617 21 will will MD cord-022526-j9kg00qf 4617 22 be be VB cord-022526-j9kg00qf 4617 23 noticeable noticeable JJ cord-022526-j9kg00qf 4617 24 following follow VBG cord-022526-j9kg00qf 4617 25 surgery surgery NN cord-022526-j9kg00qf 4617 26 because because IN cord-022526-j9kg00qf 4617 27 of of IN cord-022526-j9kg00qf 4617 28 edema edema NN cord-022526-j9kg00qf 4617 29 and and CC cord-022526-j9kg00qf 4617 30 increased increase VBN cord-022526-j9kg00qf 4617 31 temperature temperature NN cord-022526-j9kg00qf 4617 32 of of IN cord-022526-j9kg00qf 4617 33 the the DT cord-022526-j9kg00qf 4617 34 scrotum scrotum NN cord-022526-j9kg00qf 4617 35 . . . cord-022526-j9kg00qf 4618 1 Although although IN cord-022526-j9kg00qf 4618 2 umbilical umbilical JJ cord-022526-j9kg00qf 4618 3 herniae herniae NN cord-022526-j9kg00qf 4618 4 are be VBP cord-022526-j9kg00qf 4618 5 common common JJ cord-022526-j9kg00qf 4618 6 in in IN cord-022526-j9kg00qf 4618 7 foals foal NNS cord-022526-j9kg00qf 4618 8 , , , cord-022526-j9kg00qf 4618 9 strangulation strangulation NN cord-022526-j9kg00qf 4618 10 of of IN cord-022526-j9kg00qf 4618 11 herniated herniated JJ cord-022526-j9kg00qf 4618 12 bowel bowel NN cord-022526-j9kg00qf 4618 13 is be VBZ cord-022526-j9kg00qf 4618 14 rare rare JJ cord-022526-j9kg00qf 4618 15 . . . cord-022526-j9kg00qf 4619 1 In in IN cord-022526-j9kg00qf 4619 2 one one CD cord-022526-j9kg00qf 4619 3 study study NN cord-022526-j9kg00qf 4619 4 , , , cord-022526-j9kg00qf 4619 5 6 6 CD cord-022526-j9kg00qf 4619 6 of of IN cord-022526-j9kg00qf 4619 7 147 147 CD cord-022526-j9kg00qf 4619 8 ( ( -LRB- cord-022526-j9kg00qf 4619 9 4 4 CD cord-022526-j9kg00qf 4619 10 % % NN cord-022526-j9kg00qf 4619 11 ) ) -RRB- cord-022526-j9kg00qf 4619 12 horses horse NNS cord-022526-j9kg00qf 4619 13 with with IN cord-022526-j9kg00qf 4619 14 umbilical umbilical JJ cord-022526-j9kg00qf 4619 15 herniae herniae NN cord-022526-j9kg00qf 4619 16 had have VBD cord-022526-j9kg00qf 4619 17 incarcerated incarcerate VBN cord-022526-j9kg00qf 4619 18 intestine intestine NN cord-022526-j9kg00qf 4619 19 . . . cord-022526-j9kg00qf 4620 1 43 43 CD cord-022526-j9kg00qf 4620 2 Clinical clinical JJ cord-022526-j9kg00qf 4620 3 signs sign NNS cord-022526-j9kg00qf 4620 4 include include VBP cord-022526-j9kg00qf 4620 5 a a DT cord-022526-j9kg00qf 4620 6 warm warm JJ cord-022526-j9kg00qf 4620 7 , , , cord-022526-j9kg00qf 4620 8 swollen swollen JJ cord-022526-j9kg00qf 4620 9 , , , cord-022526-j9kg00qf 4620 10 firm firm JJ cord-022526-j9kg00qf 4620 11 , , , cord-022526-j9kg00qf 4620 12 and and CC cord-022526-j9kg00qf 4620 13 painful painful JJ cord-022526-j9kg00qf 4620 14 hernia hernia NN cord-022526-j9kg00qf 4620 15 sac sac NN cord-022526-j9kg00qf 4620 16 associated associate VBN cord-022526-j9kg00qf 4620 17 with with IN cord-022526-j9kg00qf 4620 18 signs sign NNS cord-022526-j9kg00qf 4620 19 of of IN cord-022526-j9kg00qf 4620 20 colic colic NN cord-022526-j9kg00qf 4620 21 . . . cord-022526-j9kg00qf 4621 1 The the DT cord-022526-j9kg00qf 4621 2 affected affected JJ cord-022526-j9kg00qf 4621 3 segment segment NN cord-022526-j9kg00qf 4621 4 of of IN cord-022526-j9kg00qf 4621 5 bowel bowel NN cord-022526-j9kg00qf 4621 6 is be VBZ cord-022526-j9kg00qf 4621 7 usually usually RB cord-022526-j9kg00qf 4621 8 small small JJ cord-022526-j9kg00qf 4621 9 intestine intestine NN cord-022526-j9kg00qf 4621 10 , , , cord-022526-j9kg00qf 4621 11 but but CC cord-022526-j9kg00qf 4621 12 herniation herniation NN cord-022526-j9kg00qf 4621 13 of of IN cord-022526-j9kg00qf 4621 14 cecum cecum NN cord-022526-j9kg00qf 4621 15 or or CC cord-022526-j9kg00qf 4621 16 large large JJ cord-022526-j9kg00qf 4621 17 colon colon NN cord-022526-j9kg00qf 4621 18 also also RB cord-022526-j9kg00qf 4621 19 has have VBZ cord-022526-j9kg00qf 4621 20 been be VBN cord-022526-j9kg00qf 4621 21 reported report VBN cord-022526-j9kg00qf 4621 22 . . . cord-022526-j9kg00qf 4622 1 In in IN cord-022526-j9kg00qf 4622 2 rare rare JJ cord-022526-j9kg00qf 4622 3 cases case NNS cord-022526-j9kg00qf 4622 4 , , , cord-022526-j9kg00qf 4622 5 one one PRP cord-022526-j9kg00qf 4622 6 may may MD cord-022526-j9kg00qf 4622 7 find find VB cord-022526-j9kg00qf 4622 8 a a DT cord-022526-j9kg00qf 4622 9 hernia hernia NN cord-022526-j9kg00qf 4622 10 that that WDT cord-022526-j9kg00qf 4622 11 involves involve VBZ cord-022526-j9kg00qf 4622 12 only only RB cord-022526-j9kg00qf 4622 13 part part NN cord-022526-j9kg00qf 4622 14 of of IN cord-022526-j9kg00qf 4622 15 the the DT cord-022526-j9kg00qf 4622 16 intestinal intestinal JJ cord-022526-j9kg00qf 4622 17 wall wall NN cord-022526-j9kg00qf 4622 18 , , , cord-022526-j9kg00qf 4622 19 called call VBD cord-022526-j9kg00qf 4622 20 a a DT cord-022526-j9kg00qf 4622 21 Richter Richter NNP cord-022526-j9kg00qf 4622 22 's 's POS cord-022526-j9kg00qf 4622 23 hernia hernia NN cord-022526-j9kg00qf 4622 24 . . . cord-022526-j9kg00qf 4623 1 In in IN cord-022526-j9kg00qf 4623 2 foals foal NNS cord-022526-j9kg00qf 4623 3 that that WDT cord-022526-j9kg00qf 4623 4 have have VBP cord-022526-j9kg00qf 4623 5 a a DT cord-022526-j9kg00qf 4623 6 Richter Richter NNP cord-022526-j9kg00qf 4623 7 's 's POS cord-022526-j9kg00qf 4623 8 hernia hernia NN cord-022526-j9kg00qf 4623 9 , , , cord-022526-j9kg00qf 4623 10 an an DT cord-022526-j9kg00qf 4623 11 enterocutaneous enterocutaneous JJ cord-022526-j9kg00qf 4623 12 fistula fistula NN cord-022526-j9kg00qf 4623 13 may may MD cord-022526-j9kg00qf 4623 14 develop develop VB cord-022526-j9kg00qf 4623 15 . . . cord-022526-j9kg00qf 4624 1 In in IN cord-022526-j9kg00qf 4624 2 one one CD cord-022526-j9kg00qf 4624 3 study study NN cord-022526-j9kg00qf 4624 4 , , , cord-022526-j9kg00qf 4624 5 13 13 CD cord-022526-j9kg00qf 4624 6 of of IN cord-022526-j9kg00qf 4624 7 13 13 CD cord-022526-j9kg00qf 4624 8 foals foal NNS cord-022526-j9kg00qf 4624 9 with with IN cord-022526-j9kg00qf 4624 10 strangulating strangulating JJ cord-022526-j9kg00qf 4624 11 umbilical umbilical JJ cord-022526-j9kg00qf 4624 12 herniae herniae NN cord-022526-j9kg00qf 4624 13 survived survive VBD cord-022526-j9kg00qf 4624 14 to to TO cord-022526-j9kg00qf 4624 15 discharge discharge VB cord-022526-j9kg00qf 4624 16 , , , cord-022526-j9kg00qf 4624 17 although although IN cord-022526-j9kg00qf 4624 18 at at RB cord-022526-j9kg00qf 4624 19 least least JJS cord-022526-j9kg00qf 4624 20 3 3 CD cord-022526-j9kg00qf 4624 21 died die VBD cord-022526-j9kg00qf 4624 22 of of IN cord-022526-j9kg00qf 4624 23 long long JJ cord-022526-j9kg00qf 4624 24 - - HYPH cord-022526-j9kg00qf 4624 25 term term NN cord-022526-j9kg00qf 4624 26 complications complication NNS cord-022526-j9kg00qf 4624 27 . . . cord-022526-j9kg00qf 4625 1 44 44 CD cord-022526-j9kg00qf 4626 1 An an DT cord-022526-j9kg00qf 4626 2 intussusception intussusception NN cord-022526-j9kg00qf 4626 3 involves involve VBZ cord-022526-j9kg00qf 4626 4 a a DT cord-022526-j9kg00qf 4626 5 segment segment NN cord-022526-j9kg00qf 4626 6 of of IN cord-022526-j9kg00qf 4626 7 bowel bowel NN cord-022526-j9kg00qf 4626 8 ( ( -LRB- cord-022526-j9kg00qf 4626 9 intussusceptum intussusceptum NNP cord-022526-j9kg00qf 4626 10 ) ) -RRB- cord-022526-j9kg00qf 4626 11 that that IN cord-022526-j9kg00qf 4626 12 invaginates invaginate VBZ cord-022526-j9kg00qf 4626 13 into into IN cord-022526-j9kg00qf 4626 14 an an DT cord-022526-j9kg00qf 4626 15 adjacent adjacent JJ cord-022526-j9kg00qf 4626 16 aboral aboral JJ cord-022526-j9kg00qf 4626 17 segment segment NN cord-022526-j9kg00qf 4626 18 of of IN cord-022526-j9kg00qf 4626 19 bowel bowel NN cord-022526-j9kg00qf 4626 20 ( ( -LRB- cord-022526-j9kg00qf 4626 21 intussuscipiens intussuscipiens NNP cord-022526-j9kg00qf 4626 22 ) ) -RRB- cord-022526-j9kg00qf 4626 23 . . . cord-022526-j9kg00qf 4627 1 The the DT cord-022526-j9kg00qf 4627 2 reason reason NN cord-022526-j9kg00qf 4627 3 for for IN cord-022526-j9kg00qf 4627 4 such such JJ cord-022526-j9kg00qf 4627 5 invagination invagination NN cord-022526-j9kg00qf 4627 6 is be VBZ cord-022526-j9kg00qf 4627 7 not not RB cord-022526-j9kg00qf 4627 8 always always RB cord-022526-j9kg00qf 4627 9 clear clear JJ cord-022526-j9kg00qf 4627 10 but but CC cord-022526-j9kg00qf 4627 11 may may MD cord-022526-j9kg00qf 4627 12 involve involve VB cord-022526-j9kg00qf 4627 13 a a DT cord-022526-j9kg00qf 4627 14 lesion lesion NN cord-022526-j9kg00qf 4627 15 at at IN cord-022526-j9kg00qf 4627 16 the the DT cord-022526-j9kg00qf 4627 17 leading leading JJ cord-022526-j9kg00qf 4627 18 edge edge NN cord-022526-j9kg00qf 4627 19 of of IN cord-022526-j9kg00qf 4627 20 the the DT cord-022526-j9kg00qf 4627 21 intussusception intussusception NN cord-022526-j9kg00qf 4627 22 , , , cord-022526-j9kg00qf 4627 23 including include VBG cord-022526-j9kg00qf 4627 24 small small JJ cord-022526-j9kg00qf 4627 25 masses masse NNS cord-022526-j9kg00qf 4627 26 , , , cord-022526-j9kg00qf 4627 27 foreign foreign JJ cord-022526-j9kg00qf 4627 28 bodies body NNS cord-022526-j9kg00qf 4627 29 , , , cord-022526-j9kg00qf 4627 30 or or CC cord-022526-j9kg00qf 4627 31 parasites parasite NNS cord-022526-j9kg00qf 4627 32 . . . cord-022526-j9kg00qf 4628 1 In in IN cord-022526-j9kg00qf 4628 2 particular particular JJ cord-022526-j9kg00qf 4628 3 , , , cord-022526-j9kg00qf 4628 4 tapeworms tapeworm NNS cord-022526-j9kg00qf 4628 5 ( ( -LRB- cord-022526-j9kg00qf 4628 6 Anoplocephala Anoplocephala NNP cord-022526-j9kg00qf 4628 7 perfoliata perfoliata NNP cord-022526-j9kg00qf 4628 8 ) ) -RRB- cord-022526-j9kg00qf 4628 9 have have VBP cord-022526-j9kg00qf 4628 10 been be VBN cord-022526-j9kg00qf 4628 11 implicated implicate VBN cord-022526-j9kg00qf 4628 12 . . . cord-022526-j9kg00qf 4629 1 45 45 CD cord-022526-j9kg00qf 4629 2 Ileocecal Ileocecal NNP cord-022526-j9kg00qf 4629 3 intussusceptions intussusception NNS cord-022526-j9kg00qf 4629 4 are be VBP cord-022526-j9kg00qf 4629 5 the the DT cord-022526-j9kg00qf 4629 6 most most RBS cord-022526-j9kg00qf 4629 7 common common JJ cord-022526-j9kg00qf 4629 8 intestinal intestinal JJ cord-022526-j9kg00qf 4629 9 intussusceptions intussusception NNS cord-022526-j9kg00qf 4629 10 in in IN cord-022526-j9kg00qf 4629 11 the the DT cord-022526-j9kg00qf 4629 12 horse horse NN cord-022526-j9kg00qf 4629 13 and and CC cord-022526-j9kg00qf 4629 14 typically typically RB cord-022526-j9kg00qf 4629 15 affect affect VB cord-022526-j9kg00qf 4629 16 young young JJ cord-022526-j9kg00qf 4629 17 animals animal NNS cord-022526-j9kg00qf 4629 18 . . . cord-022526-j9kg00qf 4630 1 In in IN cord-022526-j9kg00qf 4630 2 one one CD cord-022526-j9kg00qf 4630 3 study study NN cord-022526-j9kg00qf 4630 4 evaluating evaluate VBG cord-022526-j9kg00qf 4630 5 26 26 CD cord-022526-j9kg00qf 4630 6 cases case NNS cord-022526-j9kg00qf 4630 7 of of IN cord-022526-j9kg00qf 4630 8 ileocecal ileocecal JJ cord-022526-j9kg00qf 4630 9 intussusception intussusception NN cord-022526-j9kg00qf 4630 10 , , , cord-022526-j9kg00qf 4630 11 the the DT cord-022526-j9kg00qf 4630 12 median median JJ cord-022526-j9kg00qf 4630 13 age age NN cord-022526-j9kg00qf 4630 14 of of IN cord-022526-j9kg00qf 4630 15 the the DT cord-022526-j9kg00qf 4630 16 horses horse NNS cord-022526-j9kg00qf 4630 17 was be VBD cord-022526-j9kg00qf 4630 18 1 1 CD cord-022526-j9kg00qf 4630 19 year year NN cord-022526-j9kg00qf 4630 20 old old JJ cord-022526-j9kg00qf 4630 21 . . . cord-022526-j9kg00qf 4631 1 Acute acute JJ cord-022526-j9kg00qf 4631 2 ileocecal ileocecal JJ cord-022526-j9kg00qf 4631 3 intussusceptions intussusception NNS cord-022526-j9kg00qf 4631 4 are be VBP cord-022526-j9kg00qf 4631 5 those those DT cord-022526-j9kg00qf 4631 6 in in IN cord-022526-j9kg00qf 4631 7 which which WDT cord-022526-j9kg00qf 4631 8 the the DT cord-022526-j9kg00qf 4631 9 horses horse NNS cord-022526-j9kg00qf 4631 10 has have VBZ cord-022526-j9kg00qf 4631 11 a a DT cord-022526-j9kg00qf 4631 12 duration duration NN cord-022526-j9kg00qf 4631 13 of of IN cord-022526-j9kg00qf 4631 14 colic colic NN cord-022526-j9kg00qf 4631 15 of of IN cord-022526-j9kg00qf 4631 16 less less JJR cord-022526-j9kg00qf 4631 17 than than IN cord-022526-j9kg00qf 4631 18 24 24 CD cord-022526-j9kg00qf 4631 19 hours hour NNS cord-022526-j9kg00qf 4631 20 and and CC cord-022526-j9kg00qf 4631 21 involve involve VBP cord-022526-j9kg00qf 4631 22 variable variable JJ cord-022526-j9kg00qf 4631 23 lengths length NNS cord-022526-j9kg00qf 4631 24 of of IN cord-022526-j9kg00qf 4631 25 intestine intestine NN cord-022526-j9kg00qf 4631 26 that that WDT cord-022526-j9kg00qf 4631 27 ranged range VBD cord-022526-j9kg00qf 4631 28 in in IN cord-022526-j9kg00qf 4631 29 one one CD cord-022526-j9kg00qf 4631 30 study study NN cord-022526-j9kg00qf 4631 31 from from IN cord-022526-j9kg00qf 4631 32 6 6 CD cord-022526-j9kg00qf 4631 33 to to IN cord-022526-j9kg00qf 4631 34 457 457 CD cord-022526-j9kg00qf 4631 35 cm cm NNS cord-022526-j9kg00qf 4631 36 long long RB cord-022526-j9kg00qf 4631 37 . . . cord-022526-j9kg00qf 4632 1 In in IN cord-022526-j9kg00qf 4632 2 acute acute JJ cord-022526-j9kg00qf 4632 3 cases case NNS cord-022526-j9kg00qf 4632 4 the the DT cord-022526-j9kg00qf 4632 5 involved involve VBN cord-022526-j9kg00qf 4632 6 segment segment NN cord-022526-j9kg00qf 4632 7 of of IN cord-022526-j9kg00qf 4632 8 ileum ileum NN cord-022526-j9kg00qf 4632 9 typically typically RB cord-022526-j9kg00qf 4632 10 has have VBZ cord-022526-j9kg00qf 4632 11 a a DT cord-022526-j9kg00qf 4632 12 compromised compromise VBN cord-022526-j9kg00qf 4632 13 blood blood NN cord-022526-j9kg00qf 4632 14 supply supply NN cord-022526-j9kg00qf 4632 15 . . . cord-022526-j9kg00qf 4633 1 Chronic chronic JJ cord-022526-j9kg00qf 4633 2 ileocecal ileocecal JJ cord-022526-j9kg00qf 4633 3 intussusceptions intussusception NNS cord-022526-j9kg00qf 4633 4 typically typically RB cord-022526-j9kg00qf 4633 5 involve involve VBP cord-022526-j9kg00qf 4633 6 short short JJ cord-022526-j9kg00qf 4633 7 segments segment NNS cord-022526-j9kg00qf 4633 8 of of IN cord-022526-j9kg00qf 4633 9 ileum ileum NN cord-022526-j9kg00qf 4633 10 ( ( -LRB- cord-022526-j9kg00qf 4633 11 up up IN cord-022526-j9kg00qf 4633 12 to to TO cord-022526-j9kg00qf 4633 13 10 10 CD cord-022526-j9kg00qf 4633 14 cm cm NNS cord-022526-j9kg00qf 4633 15 long long JJ cord-022526-j9kg00qf 4633 16 ) ) -RRB- cord-022526-j9kg00qf 4633 17 , , , cord-022526-j9kg00qf 4633 18 and and CC cord-022526-j9kg00qf 4633 19 the the DT cord-022526-j9kg00qf 4633 20 ileal ileal JJ cord-022526-j9kg00qf 4633 21 blood blood NN cord-022526-j9kg00qf 4633 22 supply supply NN cord-022526-j9kg00qf 4633 23 is be VBZ cord-022526-j9kg00qf 4633 24 frequently frequently RB cord-022526-j9kg00qf 4633 25 intact intact JJ cord-022526-j9kg00qf 4633 26 . . . cord-022526-j9kg00qf 4634 1 46 46 CD cord-022526-j9kg00qf 4635 1 Abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4635 2 results result NNS cord-022526-j9kg00qf 4635 3 vary vary VBP cord-022526-j9kg00qf 4635 4 because because IN cord-022526-j9kg00qf 4635 5 strangulated strangulated JJ cord-022526-j9kg00qf 4635 6 bowel bowel NN cord-022526-j9kg00qf 4635 7 is be VBZ cord-022526-j9kg00qf 4635 8 contained contain VBN cord-022526-j9kg00qf 4635 9 within within IN cord-022526-j9kg00qf 4635 10 the the DT cord-022526-j9kg00qf 4635 11 adjacent adjacent JJ cord-022526-j9kg00qf 4635 12 bowel bowel NN cord-022526-j9kg00qf 4635 13 . . . cord-022526-j9kg00qf 4636 1 Obstruction obstruction NN cord-022526-j9kg00qf 4636 2 of of IN cord-022526-j9kg00qf 4636 3 the the DT cord-022526-j9kg00qf 4636 4 small small JJ cord-022526-j9kg00qf 4636 5 intestine intestine NN cord-022526-j9kg00qf 4636 6 often often RB cord-022526-j9kg00qf 4636 7 is be VBZ cord-022526-j9kg00qf 4636 8 evident evident JJ cord-022526-j9kg00qf 4636 9 , , , cord-022526-j9kg00qf 4636 10 including include VBG cord-022526-j9kg00qf 4636 11 nasogastric nasogastric NN cord-022526-j9kg00qf 4636 12 reflux reflux NN cord-022526-j9kg00qf 4636 13 and and CC cord-022526-j9kg00qf 4636 14 multiple multiple JJ cord-022526-j9kg00qf 4636 15 distended distended JJ cord-022526-j9kg00qf 4636 16 loops loop NNS cord-022526-j9kg00qf 4636 17 of of IN cord-022526-j9kg00qf 4636 18 small small JJ cord-022526-j9kg00qf 4636 19 intestine intestine NN cord-022526-j9kg00qf 4636 20 on on IN cord-022526-j9kg00qf 4636 21 rectal rectal JJ cord-022526-j9kg00qf 4636 22 palpation palpation NN cord-022526-j9kg00qf 4636 23 . . . cord-022526-j9kg00qf 4637 1 Horses horse NNS cord-022526-j9kg00qf 4637 2 with with IN cord-022526-j9kg00qf 4637 3 chronic chronic JJ cord-022526-j9kg00qf 4637 4 ileocecal ileocecal JJ cord-022526-j9kg00qf 4637 5 intussusceptions intussusception NNS cord-022526-j9kg00qf 4637 6 have have VBP cord-022526-j9kg00qf 4637 7 mild mild JJ cord-022526-j9kg00qf 4637 8 , , , cord-022526-j9kg00qf 4637 9 intermittent intermittent JJ cord-022526-j9kg00qf 4637 10 colic colic NN cord-022526-j9kg00qf 4637 11 , , , cord-022526-j9kg00qf 4637 12 often often RB cord-022526-j9kg00qf 4637 13 without without IN cord-022526-j9kg00qf 4637 14 evidence evidence NN cord-022526-j9kg00qf 4637 15 of of IN cord-022526-j9kg00qf 4637 16 small small JJ cord-022526-j9kg00qf 4637 17 intestinal intestinal JJ cord-022526-j9kg00qf 4637 18 obstruction obstruction NN cord-022526-j9kg00qf 4637 19 . . . cord-022526-j9kg00qf 4638 1 In in IN cord-022526-j9kg00qf 4638 2 one one CD cord-022526-j9kg00qf 4638 3 study study NN cord-022526-j9kg00qf 4638 4 , , , cord-022526-j9kg00qf 4638 5 a a DT cord-022526-j9kg00qf 4638 6 mass mass NN cord-022526-j9kg00qf 4638 7 was be VBD cord-022526-j9kg00qf 4638 8 palpated palpate VBN cord-022526-j9kg00qf 4638 9 in in IN cord-022526-j9kg00qf 4638 10 the the DT cord-022526-j9kg00qf 4638 11 region region NN cord-022526-j9kg00qf 4638 12 of of IN cord-022526-j9kg00qf 4638 13 the the DT cord-022526-j9kg00qf 4638 14 cecal cecal JJ cord-022526-j9kg00qf 4638 15 base base NN cord-022526-j9kg00qf 4638 16 in in IN cord-022526-j9kg00qf 4638 17 approximately approximately RB cord-022526-j9kg00qf 4638 18 50 50 CD cord-022526-j9kg00qf 4638 19 % % NN cord-022526-j9kg00qf 4638 20 of of IN cord-022526-j9kg00qf 4638 21 cases case NNS cord-022526-j9kg00qf 4638 22 . . . cord-022526-j9kg00qf 4639 1 45 45 CD cord-022526-j9kg00qf 4640 1 Transabdominal Transabdominal NNP cord-022526-j9kg00qf 4640 2 ultrasound ultrasound NN cord-022526-j9kg00qf 4640 3 may may MD cord-022526-j9kg00qf 4640 4 be be VB cord-022526-j9kg00qf 4640 5 helpful helpful JJ cord-022526-j9kg00qf 4640 6 in in IN cord-022526-j9kg00qf 4640 7 discerning discern VBG cord-022526-j9kg00qf 4640 8 the the DT cord-022526-j9kg00qf 4640 9 nature nature NN cord-022526-j9kg00qf 4640 10 of of IN cord-022526-j9kg00qf 4640 11 the the DT cord-022526-j9kg00qf 4640 12 mass mass NN cord-022526-j9kg00qf 4640 13 . . . cord-022526-j9kg00qf 4641 1 The the DT cord-022526-j9kg00qf 4641 2 intussusception intussusception NN cord-022526-j9kg00qf 4641 3 has have VBZ cord-022526-j9kg00qf 4641 4 a a DT cord-022526-j9kg00qf 4641 5 characteristic characteristic JJ cord-022526-j9kg00qf 4641 6 target target NN cord-022526-j9kg00qf 4641 7 appearance appearance NN cord-022526-j9kg00qf 4641 8 on on IN cord-022526-j9kg00qf 4641 9 cross cross NN cord-022526-j9kg00qf 4641 10 section section NN cord-022526-j9kg00qf 4641 11 . . . cord-022526-j9kg00qf 4642 1 47 47 CD cord-022526-j9kg00qf 4642 2 Other other JJ cord-022526-j9kg00qf 4642 3 segments segment NNS cord-022526-j9kg00qf 4642 4 of of IN cord-022526-j9kg00qf 4642 5 the the DT cord-022526-j9kg00qf 4642 6 small small JJ cord-022526-j9kg00qf 4642 7 intestine intestine NN cord-022526-j9kg00qf 4642 8 also also RB cord-022526-j9kg00qf 4642 9 may may MD cord-022526-j9kg00qf 4642 10 be be VB cord-022526-j9kg00qf 4642 11 intussuscepted intussuscept VBN cord-022526-j9kg00qf 4642 12 , , , cord-022526-j9kg00qf 4642 13 including include VBG cord-022526-j9kg00qf 4642 14 the the DT cord-022526-j9kg00qf 4642 15 jejunum jejunum NNS cord-022526-j9kg00qf 4642 16 ( ( -LRB- cord-022526-j9kg00qf 4642 17 Figure figure NN cord-022526-j9kg00qf 4642 18 13.14 13.14 CD cord-022526-j9kg00qf 4642 19 - - SYM cord-022526-j9kg00qf 4642 20 3 3 CD cord-022526-j9kg00qf 4642 21 ) ) -RRB- cord-022526-j9kg00qf 4642 22 . . . cord-022526-j9kg00qf 4643 1 In in IN cord-022526-j9kg00qf 4643 2 one one CD cord-022526-j9kg00qf 4643 3 study study NN cord-022526-j9kg00qf 4643 4 of of IN cord-022526-j9kg00qf 4643 5 11 11 CD cord-022526-j9kg00qf 4643 6 jejunojejunal jejunojejunal NNP cord-022526-j9kg00qf 4643 7 intussusceptions intussusception NNS cord-022526-j9kg00qf 4643 8 , , , cord-022526-j9kg00qf 4643 9 the the DT cord-022526-j9kg00qf 4643 10 length length NN cord-022526-j9kg00qf 4643 11 of of IN cord-022526-j9kg00qf 4643 12 bowel bowel NN cord-022526-j9kg00qf 4643 13 involved involve VBN cord-022526-j9kg00qf 4643 14 ranged range VBD cord-022526-j9kg00qf 4643 15 from from IN cord-022526-j9kg00qf 4643 16 0.4 0.4 CD cord-022526-j9kg00qf 4643 17 to to IN cord-022526-j9kg00qf 4643 18 9.1 9.1 CD cord-022526-j9kg00qf 4643 19 m. m. NN cord-022526-j9kg00qf 4643 20 48 48 CD cord-022526-j9kg00qf 4643 21 Attempts attempt NNS cord-022526-j9kg00qf 4643 22 to to TO cord-022526-j9kg00qf 4643 23 reduce reduce VB cord-022526-j9kg00qf 4643 24 intussusceptions intussusception NNS cord-022526-j9kg00qf 4643 25 at at IN cord-022526-j9kg00qf 4643 26 surgery surgery NN cord-022526-j9kg00qf 4643 27 are be VBP cord-022526-j9kg00qf 4643 28 usually usually RB cord-022526-j9kg00qf 4643 29 futile futile JJ cord-022526-j9kg00qf 4643 30 because because IN cord-022526-j9kg00qf 4643 31 of of IN cord-022526-j9kg00qf 4643 32 intramural intramural JJ cord-022526-j9kg00qf 4643 33 swelling swelling NN cord-022526-j9kg00qf 4643 34 of of IN cord-022526-j9kg00qf 4643 35 affected affected JJ cord-022526-j9kg00qf 4643 36 bowel bowel NN cord-022526-j9kg00qf 4643 37 . . . cord-022526-j9kg00qf 4644 1 One one PRP cord-022526-j9kg00qf 4644 2 should should MD cord-022526-j9kg00qf 4644 3 resect resect VB cord-022526-j9kg00qf 4644 4 jejunojejunal jejunojejunal JJ cord-022526-j9kg00qf 4644 5 intussusceptions intussusception NNS cord-022526-j9kg00qf 4644 6 . . . cord-022526-j9kg00qf 4645 1 For for IN cord-022526-j9kg00qf 4645 2 acute acute JJ cord-022526-j9kg00qf 4645 3 ileocecal ileocecal JJ cord-022526-j9kg00qf 4645 4 intussusceptions intussusception NNS cord-022526-j9kg00qf 4645 5 , , , cord-022526-j9kg00qf 4645 6 one one PRP cord-022526-j9kg00qf 4645 7 should should MD cord-022526-j9kg00qf 4645 8 transect transect VB cord-022526-j9kg00qf 4645 9 the the DT cord-022526-j9kg00qf 4645 10 small small JJ cord-022526-j9kg00qf 4645 11 intestine intestine NN cord-022526-j9kg00qf 4645 12 as as RB cord-022526-j9kg00qf 4645 13 far far RB cord-022526-j9kg00qf 4645 14 distally distally RB cord-022526-j9kg00qf 4645 15 as as IN cord-022526-j9kg00qf 4645 16 possible possible JJ cord-022526-j9kg00qf 4645 17 and and CC cord-022526-j9kg00qf 4645 18 perform perform VB cord-022526-j9kg00qf 4645 19 a a DT cord-022526-j9kg00qf 4645 20 jejunocecal jejunocecal JJ cord-022526-j9kg00qf 4645 21 anastomosis anastomosis NN cord-022526-j9kg00qf 4645 22 . . . cord-022526-j9kg00qf 4646 1 In in IN cord-022526-j9kg00qf 4646 2 horses horse NNS cord-022526-j9kg00qf 4646 3 with with IN cord-022526-j9kg00qf 4646 4 particularly particularly RB cord-022526-j9kg00qf 4646 5 long long JJ cord-022526-j9kg00qf 4646 6 intussusceptions intussusception NNS cord-022526-j9kg00qf 4646 7 ( ( -LRB- cord-022526-j9kg00qf 4646 8 up up IN cord-022526-j9kg00qf 4646 9 to to TO cord-022526-j9kg00qf 4646 10 10 10 CD cord-022526-j9kg00qf 4646 11 m m NN cord-022526-j9kg00qf 4646 12 has have VBZ cord-022526-j9kg00qf 4646 13 been be VBN cord-022526-j9kg00qf 4646 14 reported report VBN cord-022526-j9kg00qf 4646 15 ) ) -RRB- cord-022526-j9kg00qf 4646 16 , , , cord-022526-j9kg00qf 4646 17 one one PRP cord-022526-j9kg00qf 4646 18 may may MD cord-022526-j9kg00qf 4646 19 attempt attempt VB cord-022526-j9kg00qf 4646 20 an an DT cord-022526-j9kg00qf 4646 21 intracecal intracecal JJ cord-022526-j9kg00qf 4646 22 resection resection NN cord-022526-j9kg00qf 4646 23 . . . cord-022526-j9kg00qf 4647 1 49 49 CD cord-022526-j9kg00qf 4648 1 For for IN cord-022526-j9kg00qf 4648 2 horses horse NNS cord-022526-j9kg00qf 4648 3 with with IN cord-022526-j9kg00qf 4648 4 chronic chronic JJ cord-022526-j9kg00qf 4648 5 ileocecal ileocecal JJ cord-022526-j9kg00qf 4648 6 intussusceptions intussusception NNS cord-022526-j9kg00qf 4648 7 , , , cord-022526-j9kg00qf 4648 8 one one PRP cord-022526-j9kg00qf 4648 9 should should MD cord-022526-j9kg00qf 4648 10 perform perform VB cord-022526-j9kg00qf 4648 11 a a DT cord-022526-j9kg00qf 4648 12 jejunocecal jejunocecal JJ cord-022526-j9kg00qf 4648 13 bypass bypass NN cord-022526-j9kg00qf 4648 14 without without IN cord-022526-j9kg00qf 4648 15 small small JJ cord-022526-j9kg00qf 4648 16 intestinal intestinal JJ cord-022526-j9kg00qf 4648 17 transection transection NN cord-022526-j9kg00qf 4648 18 . . . cord-022526-j9kg00qf 4649 1 The the DT cord-022526-j9kg00qf 4649 2 prognosis prognosis NN cord-022526-j9kg00qf 4649 3 is be VBZ cord-022526-j9kg00qf 4649 4 good good JJ cord-022526-j9kg00qf 4649 5 for for IN cord-022526-j9kg00qf 4649 6 horses horse NNS cord-022526-j9kg00qf 4649 7 with with IN cord-022526-j9kg00qf 4649 8 chronic chronic JJ cord-022526-j9kg00qf 4649 9 ileocecal ileocecal JJ cord-022526-j9kg00qf 4649 10 intussusceptions intussusception NNS cord-022526-j9kg00qf 4649 11 and and CC cord-022526-j9kg00qf 4649 12 guarded guard VBN cord-022526-j9kg00qf 4649 13 to to IN cord-022526-j9kg00qf 4649 14 poor poor JJ cord-022526-j9kg00qf 4649 15 for for IN cord-022526-j9kg00qf 4649 16 horses horse NNS cord-022526-j9kg00qf 4649 17 with with IN cord-022526-j9kg00qf 4649 18 acute acute JJ cord-022526-j9kg00qf 4649 19 ileocecal ileocecal JJ cord-022526-j9kg00qf 4649 20 intussusceptions intussusception NNS cord-022526-j9kg00qf 4649 21 , , , cord-022526-j9kg00qf 4649 22 depending depend VBG cord-022526-j9kg00qf 4649 23 on on IN cord-022526-j9kg00qf 4649 24 the the DT cord-022526-j9kg00qf 4649 25 length length NN cord-022526-j9kg00qf 4649 26 of of IN cord-022526-j9kg00qf 4649 27 bowel bowel NN cord-022526-j9kg00qf 4649 28 involved involve VBN cord-022526-j9kg00qf 4649 29 . . . cord-022526-j9kg00qf 4650 1 46 46 CD cord-022526-j9kg00qf 4650 2 _SP cord-022526-j9kg00qf 4650 3 Herniation Herniation NNP cord-022526-j9kg00qf 4650 4 of of IN cord-022526-j9kg00qf 4650 5 intestine intestine NN cord-022526-j9kg00qf 4650 6 through through IN cord-022526-j9kg00qf 4650 7 a a DT cord-022526-j9kg00qf 4650 8 rent rent NN cord-022526-j9kg00qf 4650 9 in in IN cord-022526-j9kg00qf 4650 10 the the DT cord-022526-j9kg00qf 4650 11 diaphragm diaphragm NN cord-022526-j9kg00qf 4650 12 is be VBZ cord-022526-j9kg00qf 4650 13 rare rare JJ cord-022526-j9kg00qf 4650 14 in in IN cord-022526-j9kg00qf 4650 15 the the DT cord-022526-j9kg00qf 4650 16 horse horse NN cord-022526-j9kg00qf 4650 17 and and CC cord-022526-j9kg00qf 4650 18 may may MD cord-022526-j9kg00qf 4650 19 involve involve VB cord-022526-j9kg00qf 4650 20 any any DT cord-022526-j9kg00qf 4650 21 segment segment NN cord-022526-j9kg00qf 4650 22 of of IN cord-022526-j9kg00qf 4650 23 bowel bowel NN cord-022526-j9kg00qf 4650 24 , , , cord-022526-j9kg00qf 4650 25 although although IN cord-022526-j9kg00qf 4650 26 small small JJ cord-022526-j9kg00qf 4650 27 intestine intestine NN cord-022526-j9kg00qf 4650 28 is be VBZ cord-022526-j9kg00qf 4650 29 herniated herniate VBN cord-022526-j9kg00qf 4650 30 most most RBS cord-022526-j9kg00qf 4650 31 frequently frequently RB cord-022526-j9kg00qf 4650 32 . . . cord-022526-j9kg00qf 4651 1 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4651 2 rents rent NNS cord-022526-j9kg00qf 4651 3 may may MD cord-022526-j9kg00qf 4651 4 be be VB cord-022526-j9kg00qf 4651 5 congenital congenital JJ cord-022526-j9kg00qf 4651 6 or or CC cord-022526-j9kg00qf 4651 7 acquired acquire VBN cord-022526-j9kg00qf 4651 8 , , , cord-022526-j9kg00qf 4651 9 but but CC cord-022526-j9kg00qf 4651 10 acquired acquire VBD cord-022526-j9kg00qf 4651 11 herniae herniae NNP cord-022526-j9kg00qf 4651 12 are be VBP cord-022526-j9kg00qf 4651 13 more more RBR cord-022526-j9kg00qf 4651 14 common common JJ cord-022526-j9kg00qf 4651 15 . . . cord-022526-j9kg00qf 4652 1 Congenital congenital JJ cord-022526-j9kg00qf 4652 2 rents rent NNS cord-022526-j9kg00qf 4652 3 may may MD cord-022526-j9kg00qf 4652 4 result result VB cord-022526-j9kg00qf 4652 5 from from IN cord-022526-j9kg00qf 4652 6 incomplete incomplete JJ cord-022526-j9kg00qf 4652 7 fusion fusion NN cord-022526-j9kg00qf 4652 8 of of IN cord-022526-j9kg00qf 4652 9 any any DT cord-022526-j9kg00qf 4652 10 of of IN cord-022526-j9kg00qf 4652 11 the the DT cord-022526-j9kg00qf 4652 12 four four CD cord-022526-j9kg00qf 4652 13 embryonic embryonic JJ cord-022526-j9kg00qf 4652 14 components component NNS cord-022526-j9kg00qf 4652 15 of of IN cord-022526-j9kg00qf 4652 16 the the DT cord-022526-j9kg00qf 4652 17 diaphragm diaphragm NN cord-022526-j9kg00qf 4652 18 : : : cord-022526-j9kg00qf 4652 19 pleuroperitoneal pleuroperitoneal NN cord-022526-j9kg00qf 4652 20 membranes membrane NNS cord-022526-j9kg00qf 4652 21 , , , cord-022526-j9kg00qf 4652 22 transverse transverse JJ cord-022526-j9kg00qf 4652 23 septum septum NN cord-022526-j9kg00qf 4652 24 , , , cord-022526-j9kg00qf 4652 25 and and CC cord-022526-j9kg00qf 4652 26 esophageal esophageal JJ cord-022526-j9kg00qf 4652 27 mesentery mesentery NN cord-022526-j9kg00qf 4652 28 . . . cord-022526-j9kg00qf 4653 1 In in IN cord-022526-j9kg00qf 4653 2 addition addition NN cord-022526-j9kg00qf 4653 3 , , , cord-022526-j9kg00qf 4653 4 abdominal abdominal JJ cord-022526-j9kg00qf 4653 5 compression compression NN cord-022526-j9kg00qf 4653 6 of of IN cord-022526-j9kg00qf 4653 7 the the DT cord-022526-j9kg00qf 4653 8 foal foal NN cord-022526-j9kg00qf 4653 9 at at IN cord-022526-j9kg00qf 4653 10 parturition parturition NN cord-022526-j9kg00qf 4653 11 may may MD cord-022526-j9kg00qf 4653 12 result result VB cord-022526-j9kg00qf 4653 13 in in IN cord-022526-j9kg00qf 4653 14 a a DT cord-022526-j9kg00qf 4653 15 congenital congenital JJ cord-022526-j9kg00qf 4653 16 hernia hernia NN cord-022526-j9kg00qf 4653 17 . . . cord-022526-j9kg00qf 4654 1 50 50 CD cord-022526-j9kg00qf 4655 1 Acquired Acquired NNP cord-022526-j9kg00qf 4655 2 herniae herniae NNP cord-022526-j9kg00qf 4655 3 are be VBP cord-022526-j9kg00qf 4655 4 presumed presume VBN cord-022526-j9kg00qf 4655 5 to to TO cord-022526-j9kg00qf 4655 6 result result VB cord-022526-j9kg00qf 4655 7 from from IN cord-022526-j9kg00qf 4655 8 trauma trauma NN cord-022526-j9kg00qf 4655 9 to to IN cord-022526-j9kg00qf 4655 10 the the DT cord-022526-j9kg00qf 4655 11 chest chest NN cord-022526-j9kg00qf 4655 12 or or CC cord-022526-j9kg00qf 4655 13 a a DT cord-022526-j9kg00qf 4655 14 sudden sudden JJ cord-022526-j9kg00qf 4655 15 increase increase NN cord-022526-j9kg00qf 4655 16 in in IN cord-022526-j9kg00qf 4655 17 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 4655 18 pressure pressure NN cord-022526-j9kg00qf 4655 19 , , , cord-022526-j9kg00qf 4655 20 such such JJ cord-022526-j9kg00qf 4655 21 as as IN cord-022526-j9kg00qf 4655 22 might may MD cord-022526-j9kg00qf 4655 23 occur occur VB cord-022526-j9kg00qf 4655 24 during during IN cord-022526-j9kg00qf 4655 25 parturition parturition NN cord-022526-j9kg00qf 4655 26 , , , cord-022526-j9kg00qf 4655 27 distention distention NN cord-022526-j9kg00qf 4655 28 of of IN cord-022526-j9kg00qf 4655 29 the the DT cord-022526-j9kg00qf 4655 30 abdomen abdomen NN cord-022526-j9kg00qf 4655 31 , , , cord-022526-j9kg00qf 4655 32 a a DT cord-022526-j9kg00qf 4655 33 sudden sudden JJ cord-022526-j9kg00qf 4655 34 fall fall NN cord-022526-j9kg00qf 4655 35 , , , cord-022526-j9kg00qf 4655 36 or or CC cord-022526-j9kg00qf 4655 37 strenuous strenuous JJ cord-022526-j9kg00qf 4655 38 exercise exercise NN cord-022526-j9kg00qf 4655 39 . . . cord-022526-j9kg00qf 4656 1 51 51 CD cord-022526-j9kg00qf 4657 1 Herniae Herniae NNP cord-022526-j9kg00qf 4657 2 have have VBP cord-022526-j9kg00qf 4657 3 been be VBN cord-022526-j9kg00qf 4657 4 found find VBN cord-022526-j9kg00qf 4657 5 in in IN cord-022526-j9kg00qf 4657 6 a a DT cord-022526-j9kg00qf 4657 7 number number NN cord-022526-j9kg00qf 4657 8 of of IN cord-022526-j9kg00qf 4657 9 different different JJ cord-022526-j9kg00qf 4657 10 locations location NNS cord-022526-j9kg00qf 4657 11 , , , cord-022526-j9kg00qf 4657 12 although although IN cord-022526-j9kg00qf 4657 13 large large JJ cord-022526-j9kg00qf 4657 14 congenital congenital JJ cord-022526-j9kg00qf 4657 15 herniae herniae NN cord-022526-j9kg00qf 4657 16 are be VBP cord-022526-j9kg00qf 4657 17 typically typically RB cord-022526-j9kg00qf 4657 18 present present JJ cord-022526-j9kg00qf 4657 19 at at IN cord-022526-j9kg00qf 4657 20 the the DT cord-022526-j9kg00qf 4657 21 ventral ventral JJ cord-022526-j9kg00qf 4657 22 most most JJS cord-022526-j9kg00qf 4657 23 aspect aspect NN cord-022526-j9kg00qf 4657 24 of of IN cord-022526-j9kg00qf 4657 25 the the DT cord-022526-j9kg00qf 4657 26 diaphragm diaphragm NN cord-022526-j9kg00qf 4657 27 , , , cord-022526-j9kg00qf 4657 28 and and CC cord-022526-j9kg00qf 4657 29 most most RBS cord-022526-j9kg00qf 4657 30 acquired acquire VBN cord-022526-j9kg00qf 4657 31 herniae herniae NNP cord-022526-j9kg00qf 4657 32 are be VBP cord-022526-j9kg00qf 4657 33 located locate VBN cord-022526-j9kg00qf 4657 34 at at IN cord-022526-j9kg00qf 4657 35 the the DT cord-022526-j9kg00qf 4657 36 junction junction NN cord-022526-j9kg00qf 4657 37 of of IN cord-022526-j9kg00qf 4657 38 the the DT cord-022526-j9kg00qf 4657 39 muscular muscular JJ cord-022526-j9kg00qf 4657 40 and and CC cord-022526-j9kg00qf 4657 41 tendinous tendinous JJ cord-022526-j9kg00qf 4657 42 portions portion NNS cord-022526-j9kg00qf 4657 43 of of IN cord-022526-j9kg00qf 4657 44 the the DT cord-022526-j9kg00qf 4657 45 diaphragm diaphragm NN cord-022526-j9kg00qf 4657 46 . . . cord-022526-j9kg00qf 4658 1 50 50 CD cord-022526-j9kg00qf 4659 1 A a DT cord-022526-j9kg00qf 4659 2 peritoneopericardial peritoneopericardial JJ cord-022526-j9kg00qf 4659 3 hernia hernia NN cord-022526-j9kg00qf 4659 4 has have VBZ cord-022526-j9kg00qf 4659 5 been be VBN cord-022526-j9kg00qf 4659 6 documented document VBN cord-022526-j9kg00qf 4659 7 in in IN cord-022526-j9kg00qf 4659 8 at at RB cord-022526-j9kg00qf 4659 9 least least RBS cord-022526-j9kg00qf 4659 10 one one CD cord-022526-j9kg00qf 4659 11 horse horse NN cord-022526-j9kg00qf 4659 12 . . . cord-022526-j9kg00qf 4660 1 52 52 CD cord-022526-j9kg00qf 4660 2 Figure figure NN cord-022526-j9kg00qf 4660 3 13 13 CD cord-022526-j9kg00qf 4660 4 .14 .14 CD cord-022526-j9kg00qf 4660 5 - - SYM cord-022526-j9kg00qf 4660 6 3 3 CD cord-022526-j9kg00qf 4660 7 Jejunojejunal Jejunojejunal NNP cord-022526-j9kg00qf 4660 8 intussusception intussusception NN cord-022526-j9kg00qf 4660 9 in in IN cord-022526-j9kg00qf 4660 10 a a DT cord-022526-j9kg00qf 4660 11 horse horse NN cord-022526-j9kg00qf 4660 12 presented present VBN cord-022526-j9kg00qf 4660 13 for for IN cord-022526-j9kg00qf 4660 14 colic colic NN cord-022526-j9kg00qf 4660 15 . . . cord-022526-j9kg00qf 4661 1 The the DT cord-022526-j9kg00qf 4661 2 intussusceptum intussusceptum NN cord-022526-j9kg00qf 4661 3 has have VBZ cord-022526-j9kg00qf 4661 4 become become VBN cord-022526-j9kg00qf 4661 5 ischemic ischemic JJ cord-022526-j9kg00qf 4661 6 because because IN cord-022526-j9kg00qf 4661 7 of of IN cord-022526-j9kg00qf 4661 8 invagination invagination NN cord-022526-j9kg00qf 4661 9 of of IN cord-022526-j9kg00qf 4661 10 intestine intestine NN cord-022526-j9kg00qf 4661 11 and and CC cord-022526-j9kg00qf 4661 12 its -PRON- PRP$ cord-022526-j9kg00qf 4661 13 mesenteric mesenteric JJ cord-022526-j9kg00qf 4661 14 blood blood NN cord-022526-j9kg00qf 4661 15 supply supply NN cord-022526-j9kg00qf 4661 16 into into IN cord-022526-j9kg00qf 4661 17 the the DT cord-022526-j9kg00qf 4661 18 intussuscipiens intussuscipien NNS cord-022526-j9kg00qf 4661 19 . . . cord-022526-j9kg00qf 4662 1 Clinical clinical JJ cord-022526-j9kg00qf 4662 2 signs sign NNS cord-022526-j9kg00qf 4662 3 usually usually RB cord-022526-j9kg00qf 4662 4 are be VBP cord-022526-j9kg00qf 4662 5 associated associate VBN cord-022526-j9kg00qf 4662 6 with with IN cord-022526-j9kg00qf 4662 7 intestinal intestinal JJ cord-022526-j9kg00qf 4662 8 obstruction obstruction NN cord-022526-j9kg00qf 4662 9 rather rather RB cord-022526-j9kg00qf 4662 10 than than IN cord-022526-j9kg00qf 4662 11 respiratory respiratory JJ cord-022526-j9kg00qf 4662 12 embarrassment embarrassment NN cord-022526-j9kg00qf 4662 13 . . . cord-022526-j9kg00qf 4663 1 51 51 CD cord-022526-j9kg00qf 4664 1 However however RB cord-022526-j9kg00qf 4664 2 , , , cord-022526-j9kg00qf 4664 3 careful careful JJ cord-022526-j9kg00qf 4664 4 auscultation auscultation NN cord-022526-j9kg00qf 4664 5 may may MD cord-022526-j9kg00qf 4664 6 reveal reveal VB cord-022526-j9kg00qf 4664 7 an an DT cord-022526-j9kg00qf 4664 8 area area NN cord-022526-j9kg00qf 4664 9 of of IN cord-022526-j9kg00qf 4664 10 decreased decrease VBN cord-022526-j9kg00qf 4664 11 lung lung NN cord-022526-j9kg00qf 4664 12 sounds sound VBZ cord-022526-j9kg00qf 4664 13 associated associate VBN cord-022526-j9kg00qf 4664 14 with with IN cord-022526-j9kg00qf 4664 15 obstructed obstruct VBN cord-022526-j9kg00qf 4664 16 intestine intestine NN cord-022526-j9kg00qf 4664 17 and and CC cord-022526-j9kg00qf 4664 18 increased increase VBN cord-022526-j9kg00qf 4664 19 fluid fluid NN cord-022526-j9kg00qf 4664 20 within within IN cord-022526-j9kg00qf 4664 21 the the DT cord-022526-j9kg00qf 4664 22 chest chest NN cord-022526-j9kg00qf 4664 23 cavity cavity NN cord-022526-j9kg00qf 4664 24 . . . cord-022526-j9kg00qf 4665 1 53 53 CD cord-022526-j9kg00qf 4666 1 Such such JJ cord-022526-j9kg00qf 4666 2 signs sign NNS cord-022526-j9kg00qf 4666 3 may may MD cord-022526-j9kg00qf 4666 4 prompt prompt VB cord-022526-j9kg00qf 4666 5 thoracic thoracic JJ cord-022526-j9kg00qf 4666 6 radiography radiography NN cord-022526-j9kg00qf 4666 7 or or CC cord-022526-j9kg00qf 4666 8 ultrasound ultrasound NN cord-022526-j9kg00qf 4666 9 , , , cord-022526-j9kg00qf 4666 10 both both DT cord-022526-j9kg00qf 4666 11 of of IN cord-022526-j9kg00qf 4666 12 which which WDT cord-022526-j9kg00qf 4666 13 one one PRP cord-022526-j9kg00qf 4666 14 can can MD cord-022526-j9kg00qf 4666 15 use use VB cord-022526-j9kg00qf 4666 16 to to TO cord-022526-j9kg00qf 4666 17 make make VB cord-022526-j9kg00qf 4666 18 a a DT cord-022526-j9kg00qf 4666 19 diagnosis diagnosis NN cord-022526-j9kg00qf 4666 20 . . . cord-022526-j9kg00qf 4667 1 Auscultation Auscultation NNP cord-022526-j9kg00qf 4667 2 also also RB cord-022526-j9kg00qf 4667 3 may may MD cord-022526-j9kg00qf 4667 4 reveal reveal VB cord-022526-j9kg00qf 4667 5 thoracic thoracic JJ cord-022526-j9kg00qf 4667 6 intestinal intestinal JJ cord-022526-j9kg00qf 4667 7 sounds sound NNS cord-022526-j9kg00qf 4667 8 , , , cord-022526-j9kg00qf 4667 9 but but CC cord-022526-j9kg00qf 4667 10 differentiating differentiate VBG cord-022526-j9kg00qf 4667 11 these these DT cord-022526-j9kg00qf 4667 12 from from IN cord-022526-j9kg00qf 4667 13 sounds sound NNS cord-022526-j9kg00qf 4667 14 referred refer VBN cord-022526-j9kg00qf 4667 15 from from IN cord-022526-j9kg00qf 4667 16 the the DT cord-022526-j9kg00qf 4667 17 abdomen abdomen NN cord-022526-j9kg00qf 4667 18 typically typically RB cord-022526-j9kg00qf 4667 19 is be VBZ cord-022526-j9kg00qf 4667 20 not not RB cord-022526-j9kg00qf 4667 21 possible possible JJ cord-022526-j9kg00qf 4667 22 . . . cord-022526-j9kg00qf 4668 1 In in IN cord-022526-j9kg00qf 4668 2 one one CD cord-022526-j9kg00qf 4668 3 report report NN cord-022526-j9kg00qf 4668 4 , , , cord-022526-j9kg00qf 4668 5 two two CD cord-022526-j9kg00qf 4668 6 of of IN cord-022526-j9kg00qf 4668 7 three three CD cord-022526-j9kg00qf 4668 8 horses horse NNS cord-022526-j9kg00qf 4668 9 diagnosed diagnose VBN cord-022526-j9kg00qf 4668 10 with with IN cord-022526-j9kg00qf 4668 11 small small JJ cord-022526-j9kg00qf 4668 12 intestinal intestinal JJ cord-022526-j9kg00qf 4668 13 strangulation strangulation NN cord-022526-j9kg00qf 4668 14 by by IN cord-022526-j9kg00qf 4668 15 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4668 16 hernia hernia NN cord-022526-j9kg00qf 4668 17 had have VBD cord-022526-j9kg00qf 4668 18 respiratory respiratory JJ cord-022526-j9kg00qf 4668 19 acidemia acidemia NN cord-022526-j9kg00qf 4668 20 attributable attributable JJ cord-022526-j9kg00qf 4668 21 to to IN cord-022526-j9kg00qf 4668 22 decreased decrease VBN cord-022526-j9kg00qf 4668 23 ventilation ventilation NN cord-022526-j9kg00qf 4668 24 . . . cord-022526-j9kg00qf 4669 1 54 54 CD cord-022526-j9kg00qf 4669 2 Treatment treatment NN cord-022526-j9kg00qf 4669 3 of of IN cord-022526-j9kg00qf 4669 4 horses horse NNS cord-022526-j9kg00qf 4669 5 with with IN cord-022526-j9kg00qf 4669 6 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4669 7 hernia hernia NN cord-022526-j9kg00qf 4669 8 is be VBZ cord-022526-j9kg00qf 4669 9 fraught fraught JJ cord-022526-j9kg00qf 4669 10 with with IN cord-022526-j9kg00qf 4669 11 complications complication NNS cord-022526-j9kg00qf 4669 12 because because IN cord-022526-j9kg00qf 4669 13 of of IN cord-022526-j9kg00qf 4669 14 the the DT cord-022526-j9kg00qf 4669 15 need need NN cord-022526-j9kg00qf 4669 16 to to TO cord-022526-j9kg00qf 4669 17 reduce reduce VB cord-022526-j9kg00qf 4669 18 and and CC cord-022526-j9kg00qf 4669 19 resect resect VB cord-022526-j9kg00qf 4669 20 strangulated strangulated JJ cord-022526-j9kg00qf 4669 21 bowel bowel NN cord-022526-j9kg00qf 4669 22 and and CC cord-022526-j9kg00qf 4669 23 the the DT cord-022526-j9kg00qf 4669 24 need need NN cord-022526-j9kg00qf 4669 25 to to TO cord-022526-j9kg00qf 4669 26 repair repair VB cord-022526-j9kg00qf 4669 27 the the DT cord-022526-j9kg00qf 4669 28 defect defect NN cord-022526-j9kg00qf 4669 29 in in IN cord-022526-j9kg00qf 4669 30 the the DT cord-022526-j9kg00qf 4669 31 diaphragm diaphragm NN cord-022526-j9kg00qf 4669 32 . . . cord-022526-j9kg00qf 4670 1 55 55 CD cord-022526-j9kg00qf 4670 2 , , , cord-022526-j9kg00qf 4670 3 56 56 CD cord-022526-j9kg00qf 4671 1 Because because IN cord-022526-j9kg00qf 4671 2 dorsal dorsal JJ cord-022526-j9kg00qf 4671 3 defects defect NNS cord-022526-j9kg00qf 4671 4 in in IN cord-022526-j9kg00qf 4671 5 the the DT cord-022526-j9kg00qf 4671 6 diaphragm diaphragm NN cord-022526-j9kg00qf 4671 7 are be VBP cord-022526-j9kg00qf 4671 8 among among IN cord-022526-j9kg00qf 4671 9 the the DT cord-022526-j9kg00qf 4671 10 common common JJ cord-022526-j9kg00qf 4671 11 forms form NNS cord-022526-j9kg00qf 4671 12 of of IN cord-022526-j9kg00qf 4671 13 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4671 14 defect defect NN cord-022526-j9kg00qf 4671 15 , , , cord-022526-j9kg00qf 4671 16 closing close VBG cord-022526-j9kg00qf 4671 17 the the DT cord-022526-j9kg00qf 4671 18 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4671 19 hernia hernia NN cord-022526-j9kg00qf 4671 20 via via IN cord-022526-j9kg00qf 4671 21 the the DT cord-022526-j9kg00qf 4671 22 approach approach NN cord-022526-j9kg00qf 4671 23 used use VBN cord-022526-j9kg00qf 4671 24 for for IN cord-022526-j9kg00qf 4671 25 abdominal abdominal JJ cord-022526-j9kg00qf 4671 26 exploration exploration NN cord-022526-j9kg00qf 4671 27 may may MD cord-022526-j9kg00qf 4671 28 not not RB cord-022526-j9kg00qf 4671 29 be be VB cord-022526-j9kg00qf 4671 30 possible possible JJ cord-022526-j9kg00qf 4671 31 . . . cord-022526-j9kg00qf 4672 1 However however RB cord-022526-j9kg00qf 4672 2 , , , cord-022526-j9kg00qf 4672 3 because because IN cord-022526-j9kg00qf 4672 4 herniation herniation NN cord-022526-j9kg00qf 4672 5 is be VBZ cord-022526-j9kg00qf 4672 6 likely likely JJ cord-022526-j9kg00qf 4672 7 to to TO cord-022526-j9kg00qf 4672 8 recur recur VB cord-022526-j9kg00qf 4672 9 , , , cord-022526-j9kg00qf 4672 10 55 55 CD cord-022526-j9kg00qf 4672 11 scheduling scheduling NN cord-022526-j9kg00qf 4672 12 a a DT cord-022526-j9kg00qf 4672 13 second second JJ cord-022526-j9kg00qf 4672 14 surgery surgery NN cord-022526-j9kg00qf 4672 15 using use VBG cord-022526-j9kg00qf 4672 16 an an DT cord-022526-j9kg00qf 4672 17 appropriate appropriate JJ cord-022526-j9kg00qf 4672 18 approach approach NN cord-022526-j9kg00qf 4672 19 to to TO cord-022526-j9kg00qf 4672 20 resolve resolve VB cord-022526-j9kg00qf 4672 21 the the DT cord-022526-j9kg00qf 4672 22 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4672 23 defect defect NN cord-022526-j9kg00qf 4672 24 is be VBZ cord-022526-j9kg00qf 4672 25 appropriate appropriate JJ cord-022526-j9kg00qf 4672 26 . . . cord-022526-j9kg00qf 4673 1 Horses horse NNS cord-022526-j9kg00qf 4673 2 with with IN cord-022526-j9kg00qf 4673 3 large large JJ cord-022526-j9kg00qf 4673 4 colon colon NN cord-022526-j9kg00qf 4673 5 volvulus volvulus NN cord-022526-j9kg00qf 4673 6 have have VBP cord-022526-j9kg00qf 4673 7 rapid rapid JJ cord-022526-j9kg00qf 4673 8 onset onset NN cord-022526-j9kg00qf 4673 9 of of IN cord-022526-j9kg00qf 4673 10 severe severe JJ cord-022526-j9kg00qf 4673 11 , , , cord-022526-j9kg00qf 4673 12 unrelenting unrelenting JJ cord-022526-j9kg00qf 4673 13 abdominal abdominal JJ cord-022526-j9kg00qf 4673 14 pain pain NN cord-022526-j9kg00qf 4673 15 , , , cord-022526-j9kg00qf 4673 16 most most RBS cord-022526-j9kg00qf 4673 17 often often RB cord-022526-j9kg00qf 4673 18 in in IN cord-022526-j9kg00qf 4673 19 postpartum postpartum NN cord-022526-j9kg00qf 4673 20 broodmares broodmare NNS cord-022526-j9kg00qf 4673 21 . . . cord-022526-j9kg00qf 4674 1 4 4 LS cord-022526-j9kg00qf 4675 1 Once once IN cord-022526-j9kg00qf 4675 2 the the DT cord-022526-j9kg00qf 4675 3 large large JJ cord-022526-j9kg00qf 4675 4 colon colon NN cord-022526-j9kg00qf 4675 5 strangulates strangulate NNS cord-022526-j9kg00qf 4675 6 ( ( -LRB- cord-022526-j9kg00qf 4675 7 ≥270-degree ≥270-degree NNP cord-022526-j9kg00qf 4675 8 volvulus volvulus NN cord-022526-j9kg00qf 4675 9 ) ) -RRB- cord-022526-j9kg00qf 4675 10 , , , cord-022526-j9kg00qf 4675 11 gas gas NN cord-022526-j9kg00qf 4675 12 distention distention NN cord-022526-j9kg00qf 4675 13 is be VBZ cord-022526-j9kg00qf 4675 14 significant significant JJ cord-022526-j9kg00qf 4675 15 , , , cord-022526-j9kg00qf 4675 16 leading lead VBG cord-022526-j9kg00qf 4675 17 to to IN cord-022526-j9kg00qf 4675 18 gross gross JJ cord-022526-j9kg00qf 4675 19 distention distention NN cord-022526-j9kg00qf 4675 20 of of IN cord-022526-j9kg00qf 4675 21 the the DT cord-022526-j9kg00qf 4675 22 abdomen abdomen NN cord-022526-j9kg00qf 4675 23 , , , cord-022526-j9kg00qf 4675 24 compromised compromise VBN cord-022526-j9kg00qf 4675 25 respiration respiration NN cord-022526-j9kg00qf 4675 26 as as IN cord-022526-j9kg00qf 4675 27 the the DT cord-022526-j9kg00qf 4675 28 distended distended JJ cord-022526-j9kg00qf 4675 29 bowel bowel NN cord-022526-j9kg00qf 4675 30 presses press VBZ cord-022526-j9kg00qf 4675 31 up up RP cord-022526-j9kg00qf 4675 32 against against IN cord-022526-j9kg00qf 4675 33 the the DT cord-022526-j9kg00qf 4675 34 diaphragm diaphragm NN cord-022526-j9kg00qf 4675 35 , , , cord-022526-j9kg00qf 4675 36 and and CC cord-022526-j9kg00qf 4675 37 visceral visceral JJ cord-022526-j9kg00qf 4675 38 pooling pooling NN cord-022526-j9kg00qf 4675 39 of of IN cord-022526-j9kg00qf 4675 40 blood blood NN cord-022526-j9kg00qf 4675 41 as as IN cord-022526-j9kg00qf 4675 42 the the DT cord-022526-j9kg00qf 4675 43 caudal caudal JJ cord-022526-j9kg00qf 4675 44 vena vena FW cord-022526-j9kg00qf 4675 45 cava cava NNP cord-022526-j9kg00qf 4675 46 is be VBZ cord-022526-j9kg00qf 4675 47 compressed compress VBN cord-022526-j9kg00qf 4675 48 . . . cord-022526-j9kg00qf 4676 1 Horses horse NNS cord-022526-j9kg00qf 4676 2 with with IN cord-022526-j9kg00qf 4676 3 this this DT cord-022526-j9kg00qf 4676 4 condition condition NN cord-022526-j9kg00qf 4676 5 are be VBP cord-022526-j9kg00qf 4676 6 frequently frequently RB cord-022526-j9kg00qf 4676 7 refractory refractory JJ cord-022526-j9kg00qf 4676 8 even even RB cord-022526-j9kg00qf 4676 9 to to IN cord-022526-j9kg00qf 4676 10 the the DT cord-022526-j9kg00qf 4676 11 most most RBS cord-022526-j9kg00qf 4676 12 potent potent JJ cord-022526-j9kg00qf 4676 13 of of IN cord-022526-j9kg00qf 4676 14 analgesics analgesic NNS cord-022526-j9kg00qf 4676 15 . . . cord-022526-j9kg00qf 4677 1 These these DT cord-022526-j9kg00qf 4677 2 horses horse NNS cord-022526-j9kg00qf 4677 3 may may MD cord-022526-j9kg00qf 4677 4 prefer prefer VB cord-022526-j9kg00qf 4677 5 to to TO cord-022526-j9kg00qf 4677 6 lie lie VB cord-022526-j9kg00qf 4677 7 in in IN cord-022526-j9kg00qf 4677 8 dorsal dorsal JJ cord-022526-j9kg00qf 4677 9 recumbency recumbency NN cord-022526-j9kg00qf 4677 10 , , , cord-022526-j9kg00qf 4677 11 presumably presumably RB cord-022526-j9kg00qf 4677 12 to to TO cord-022526-j9kg00qf 4677 13 take take VB cord-022526-j9kg00qf 4677 14 weight weight NN cord-022526-j9kg00qf 4677 15 off off IN cord-022526-j9kg00qf 4677 16 the the DT cord-022526-j9kg00qf 4677 17 strangulated strangulated JJ cord-022526-j9kg00qf 4677 18 colon colon NN cord-022526-j9kg00qf 4677 19 . . . cord-022526-j9kg00qf 4678 1 An an DT cord-022526-j9kg00qf 4678 2 abbreviated abbreviated JJ cord-022526-j9kg00qf 4678 3 physical physical JJ cord-022526-j9kg00qf 4678 4 examination examination NN cord-022526-j9kg00qf 4678 5 is be VBZ cord-022526-j9kg00qf 4678 6 warranted warrant VBN cord-022526-j9kg00qf 4678 7 in in IN cord-022526-j9kg00qf 4678 8 these these DT cord-022526-j9kg00qf 4678 9 cases case NNS cord-022526-j9kg00qf 4678 10 , , , cord-022526-j9kg00qf 4678 11 because because IN cord-022526-j9kg00qf 4678 12 the the DT cord-022526-j9kg00qf 4678 13 time time NN cord-022526-j9kg00qf 4678 14 elapsed elapse VBN cord-022526-j9kg00qf 4678 15 from from IN cord-022526-j9kg00qf 4678 16 the the DT cord-022526-j9kg00qf 4678 17 onset onset NN cord-022526-j9kg00qf 4678 18 of of IN cord-022526-j9kg00qf 4678 19 strangulation strangulation NN cord-022526-j9kg00qf 4678 20 to to IN cord-022526-j9kg00qf 4678 21 surgical surgical JJ cord-022526-j9kg00qf 4678 22 correction correction NN cord-022526-j9kg00qf 4678 23 is be VBZ cord-022526-j9kg00qf 4678 24 critical critical JJ cord-022526-j9kg00qf 4678 25 . . . cord-022526-j9kg00qf 4679 1 Under under IN cord-022526-j9kg00qf 4679 2 experimental experimental JJ cord-022526-j9kg00qf 4679 3 conditions condition NNS cord-022526-j9kg00qf 4679 4 , , , cord-022526-j9kg00qf 4679 5 the the DT cord-022526-j9kg00qf 4679 6 colon colon NN cord-022526-j9kg00qf 4679 7 is be VBZ cord-022526-j9kg00qf 4679 8 irreversibly irreversibly RB cord-022526-j9kg00qf 4679 9 damaged damage VBN cord-022526-j9kg00qf 4679 10 within within IN cord-022526-j9kg00qf 4679 11 3 3 CD cord-022526-j9kg00qf 4679 12 to to IN cord-022526-j9kg00qf 4679 13 4 4 CD cord-022526-j9kg00qf 4679 14 hours hour NNS cord-022526-j9kg00qf 4679 15 of of IN cord-022526-j9kg00qf 4679 16 a a DT cord-022526-j9kg00qf 4679 17 360-degree 360-degree CD cord-022526-j9kg00qf 4679 18 volvulus volvulus NN cord-022526-j9kg00qf 4679 19 of of IN cord-022526-j9kg00qf 4679 20 the the DT cord-022526-j9kg00qf 4679 21 entire entire JJ cord-022526-j9kg00qf 4679 22 colon colon NN cord-022526-j9kg00qf 4679 23 . . . cord-022526-j9kg00qf 4680 1 57 57 CD cord-022526-j9kg00qf 4681 1 Despite despite IN cord-022526-j9kg00qf 4681 2 severe severe JJ cord-022526-j9kg00qf 4681 3 pain pain NN cord-022526-j9kg00qf 4681 4 and and CC cord-022526-j9kg00qf 4681 5 hypovolemia hypovolemia NN cord-022526-j9kg00qf 4681 6 , , , cord-022526-j9kg00qf 4681 7 horses horse NNS cord-022526-j9kg00qf 4681 8 may may MD cord-022526-j9kg00qf 4681 9 have have VB cord-022526-j9kg00qf 4681 10 a a DT cord-022526-j9kg00qf 4681 11 paradoxically paradoxically RB cord-022526-j9kg00qf 4681 12 low low JJ cord-022526-j9kg00qf 4681 13 heart heart NN cord-022526-j9kg00qf 4681 14 rate rate NN cord-022526-j9kg00qf 4681 15 , , , cord-022526-j9kg00qf 4681 16 possibly possibly RB cord-022526-j9kg00qf 4681 17 related relate VBN cord-022526-j9kg00qf 4681 18 to to IN cord-022526-j9kg00qf 4681 19 increased increase VBN cord-022526-j9kg00qf 4681 20 vagal vagal JJ cord-022526-j9kg00qf 4681 21 tone tone NN cord-022526-j9kg00qf 4681 22 . . . cord-022526-j9kg00qf 4682 1 In in IN cord-022526-j9kg00qf 4682 2 addition addition NN cord-022526-j9kg00qf 4682 3 , , , cord-022526-j9kg00qf 4682 4 results result NNS cord-022526-j9kg00qf 4682 5 of of IN cord-022526-j9kg00qf 4682 6 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4682 7 often often RB cord-022526-j9kg00qf 4682 8 do do VBP cord-022526-j9kg00qf 4682 9 not not RB cord-022526-j9kg00qf 4682 10 indicate indicate VB cord-022526-j9kg00qf 4682 11 the the DT cord-022526-j9kg00qf 4682 12 degree degree NN cord-022526-j9kg00qf 4682 13 of of IN cord-022526-j9kg00qf 4682 14 colonic colonic JJ cord-022526-j9kg00qf 4682 15 compromise compromise NN cord-022526-j9kg00qf 4682 16 4,58 4,58 CD cord-022526-j9kg00qf 4682 17 and and CC cord-022526-j9kg00qf 4682 18 in in IN cord-022526-j9kg00qf 4682 19 many many JJ cord-022526-j9kg00qf 4682 20 cases case NNS cord-022526-j9kg00qf 4682 21 are be VBP cord-022526-j9kg00qf 4682 22 not not RB cord-022526-j9kg00qf 4682 23 worth worth JJ cord-022526-j9kg00qf 4682 24 attempting attempt VBG cord-022526-j9kg00qf 4682 25 because because IN cord-022526-j9kg00qf 4682 26 of of IN cord-022526-j9kg00qf 4682 27 extreme extreme JJ cord-022526-j9kg00qf 4682 28 colonic colonic JJ cord-022526-j9kg00qf 4682 29 distention distention NN cord-022526-j9kg00qf 4682 30 . . . cord-022526-j9kg00qf 4683 1 59 59 CD cord-022526-j9kg00qf 4684 1 Palpation palpation NN cord-022526-j9kg00qf 4684 2 per per IN cord-022526-j9kg00qf 4684 3 rectum rectum NN cord-022526-j9kg00qf 4684 4 reveals reveal VBZ cord-022526-j9kg00qf 4684 5 severe severe JJ cord-022526-j9kg00qf 4684 6 gas gas NN cord-022526-j9kg00qf 4684 7 distention distention NN cord-022526-j9kg00qf 4684 8 of of IN cord-022526-j9kg00qf 4684 9 the the DT cord-022526-j9kg00qf 4684 10 large large JJ cord-022526-j9kg00qf 4684 11 colon colon NN cord-022526-j9kg00qf 4684 12 , , , cord-022526-j9kg00qf 4684 13 often often RB cord-022526-j9kg00qf 4684 14 restricting restrict VBG cord-022526-j9kg00qf 4684 15 access access NN cord-022526-j9kg00qf 4684 16 to to IN cord-022526-j9kg00qf 4684 17 the the DT cord-022526-j9kg00qf 4684 18 abdomen abdomen NN cord-022526-j9kg00qf 4684 19 beyond beyond IN cord-022526-j9kg00qf 4684 20 the the DT cord-022526-j9kg00qf 4684 21 pelvic pelvic JJ cord-022526-j9kg00qf 4684 22 brim brim NN cord-022526-j9kg00qf 4684 23 . . . cord-022526-j9kg00qf 4685 1 One one CD cord-022526-j9kg00qf 4685 2 may may MD cord-022526-j9kg00qf 4685 3 make make VB cord-022526-j9kg00qf 4685 4 the the DT cord-022526-j9kg00qf 4685 5 diagnosis diagnosis NN cord-022526-j9kg00qf 4685 6 tentatively tentatively RB cord-022526-j9kg00qf 4685 7 based base VBN cord-022526-j9kg00qf 4685 8 on on IN cord-022526-j9kg00qf 4685 9 signalment signalment JJ cord-022526-j9kg00qf 4685 10 , , , cord-022526-j9kg00qf 4685 11 severity severity NN cord-022526-j9kg00qf 4685 12 of of IN cord-022526-j9kg00qf 4685 13 pain pain NN cord-022526-j9kg00qf 4685 14 , , , cord-022526-j9kg00qf 4685 15 and and CC cord-022526-j9kg00qf 4685 16 degree degree NN cord-022526-j9kg00qf 4685 17 of of IN cord-022526-j9kg00qf 4685 18 distention distention NN cord-022526-j9kg00qf 4685 19 . . . cord-022526-j9kg00qf 4686 1 At at IN cord-022526-j9kg00qf 4686 2 surgery surgery NN cord-022526-j9kg00qf 4686 3 , , , cord-022526-j9kg00qf 4686 4 the the DT cord-022526-j9kg00qf 4686 5 volvulus volvulus NN cord-022526-j9kg00qf 4686 6 typically typically RB cord-022526-j9kg00qf 4686 7 is be VBZ cord-022526-j9kg00qf 4686 8 located locate VBN cord-022526-j9kg00qf 4686 9 at at IN cord-022526-j9kg00qf 4686 10 the the DT cord-022526-j9kg00qf 4686 11 mesenteric mesenteric JJ cord-022526-j9kg00qf 4686 12 attachment attachment NN cord-022526-j9kg00qf 4686 13 of of IN cord-022526-j9kg00qf 4686 14 the the DT cord-022526-j9kg00qf 4686 15 colon colon NN cord-022526-j9kg00qf 4686 16 to to IN cord-022526-j9kg00qf 4686 17 the the DT cord-022526-j9kg00qf 4686 18 dorsal dorsal JJ cord-022526-j9kg00qf 4686 19 body body NN cord-022526-j9kg00qf 4686 20 wall wall NN cord-022526-j9kg00qf 4686 21 and and CC cord-022526-j9kg00qf 4686 22 the the DT cord-022526-j9kg00qf 4686 23 most most RBS cord-022526-j9kg00qf 4686 24 common common JJ cord-022526-j9kg00qf 4686 25 direction direction NN cord-022526-j9kg00qf 4686 26 of of IN cord-022526-j9kg00qf 4686 27 the the DT cord-022526-j9kg00qf 4686 28 twist twist NN cord-022526-j9kg00qf 4686 29 is be VBZ cord-022526-j9kg00qf 4686 30 dorsomedial dorsomedial NN cord-022526-j9kg00qf 4686 31 using use VBG cord-022526-j9kg00qf 4686 32 the the DT cord-022526-j9kg00qf 4686 33 right right JJ cord-022526-j9kg00qf 4686 34 ventral ventral JJ cord-022526-j9kg00qf 4686 35 colon colon NN cord-022526-j9kg00qf 4686 36 as as IN cord-022526-j9kg00qf 4686 37 a a DT cord-022526-j9kg00qf 4686 38 reference reference NN cord-022526-j9kg00qf 4686 39 point point NN cord-022526-j9kg00qf 4686 40 . . . cord-022526-j9kg00qf 4687 1 However however RB cord-022526-j9kg00qf 4687 2 , , , cord-022526-j9kg00qf 4687 3 the the DT cord-022526-j9kg00qf 4687 4 colon colon NN cord-022526-j9kg00qf 4687 5 may may MD cord-022526-j9kg00qf 4687 6 twist twist VB cord-022526-j9kg00qf 4687 7 in in IN cord-022526-j9kg00qf 4687 8 the the DT cord-022526-j9kg00qf 4687 9 opposite opposite JJ cord-022526-j9kg00qf 4687 10 direction direction NN cord-022526-j9kg00qf 4687 11 , , , cord-022526-j9kg00qf 4687 12 twist twist VB cord-022526-j9kg00qf 4687 13 greater great JJR cord-022526-j9kg00qf 4687 14 than than IN cord-022526-j9kg00qf 4687 15 360 360 CD cord-022526-j9kg00qf 4687 16 degrees degree NNS cord-022526-j9kg00qf 4687 17 ( ( -LRB- cord-022526-j9kg00qf 4687 18 up up IN cord-022526-j9kg00qf 4687 19 to to TO cord-022526-j9kg00qf 4687 20 720 720 CD cord-022526-j9kg00qf 4687 21 degrees degree NNS cord-022526-j9kg00qf 4687 22 has have VBZ cord-022526-j9kg00qf 4687 23 been be VBN cord-022526-j9kg00qf 4687 24 reported report VBN cord-022526-j9kg00qf 4687 25 ) ) -RRB- cord-022526-j9kg00qf 4687 26 or or CC cord-022526-j9kg00qf 4687 27 twist twist VB cord-022526-j9kg00qf 4687 28 at at IN cord-022526-j9kg00qf 4687 29 the the DT cord-022526-j9kg00qf 4687 30 level level NN cord-022526-j9kg00qf 4687 31 of of IN cord-022526-j9kg00qf 4687 32 the the DT cord-022526-j9kg00qf 4687 33 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 4687 34 and and CC cord-022526-j9kg00qf 4687 35 sternal sternal JJ cord-022526-j9kg00qf 4687 36 flexures flexure NNS cord-022526-j9kg00qf 4687 37 . . . cord-022526-j9kg00qf 4688 1 4 4 LS cord-022526-j9kg00qf 4689 1 In in IN cord-022526-j9kg00qf 4689 2 all all DT cord-022526-j9kg00qf 4689 3 cases case NNS cord-022526-j9kg00qf 4689 4 , , , cord-022526-j9kg00qf 4689 5 one one PRP cord-022526-j9kg00qf 4689 6 should should MD cord-022526-j9kg00qf 4689 7 decompress decompress VB cord-022526-j9kg00qf 4689 8 the the DT cord-022526-j9kg00qf 4689 9 colon colon NN cord-022526-j9kg00qf 4689 10 as as RB cord-022526-j9kg00qf 4689 11 much much RB cord-022526-j9kg00qf 4689 12 as as IN cord-022526-j9kg00qf 4689 13 possible possible JJ cord-022526-j9kg00qf 4689 14 , , , cord-022526-j9kg00qf 4689 15 and and CC cord-022526-j9kg00qf 4689 16 in in IN cord-022526-j9kg00qf 4689 17 many many JJ cord-022526-j9kg00qf 4689 18 cases case NNS cord-022526-j9kg00qf 4689 19 a a DT cord-022526-j9kg00qf 4689 20 colonic colonic JJ cord-022526-j9kg00qf 4689 21 evacuation evacuation NN cord-022526-j9kg00qf 4689 22 via via IN cord-022526-j9kg00qf 4689 23 a a DT cord-022526-j9kg00qf 4689 24 pelvic pelvic JJ cord-022526-j9kg00qf 4689 25 flexure flexure NN cord-022526-j9kg00qf 4689 26 enterotomy enterotomy NNP cord-022526-j9kg00qf 4689 27 greatly greatly RB cord-022526-j9kg00qf 4689 28 aids aid VBZ cord-022526-j9kg00qf 4689 29 correction correction NN cord-022526-j9kg00qf 4689 30 of of IN cord-022526-j9kg00qf 4689 31 the the DT cord-022526-j9kg00qf 4689 32 volvulus volvulus NN cord-022526-j9kg00qf 4689 33 . . . cord-022526-j9kg00qf 4690 1 One one PRP cord-022526-j9kg00qf 4690 2 must must MD cord-022526-j9kg00qf 4690 3 determine determine VB cord-022526-j9kg00qf 4690 4 after after IN cord-022526-j9kg00qf 4690 5 correction correction NN cord-022526-j9kg00qf 4690 6 of of IN cord-022526-j9kg00qf 4690 7 the the DT cord-022526-j9kg00qf 4690 8 volvulus volvulus NN cord-022526-j9kg00qf 4690 9 whether whether IN cord-022526-j9kg00qf 4690 10 the the DT cord-022526-j9kg00qf 4690 11 colon colon NN cord-022526-j9kg00qf 4690 12 has have VBZ cord-022526-j9kg00qf 4690 13 been be VBN cord-022526-j9kg00qf 4690 14 injured injure VBN cord-022526-j9kg00qf 4690 15 irreversibly irreversibly RB cord-022526-j9kg00qf 4690 16 and and CC cord-022526-j9kg00qf 4690 17 should should MD cord-022526-j9kg00qf 4690 18 base base VB cord-022526-j9kg00qf 4690 19 the the DT cord-022526-j9kg00qf 4690 20 determination determination NN cord-022526-j9kg00qf 4690 21 on on IN cord-022526-j9kg00qf 4690 22 mucosal mucosal JJ cord-022526-j9kg00qf 4690 23 color color NN cord-022526-j9kg00qf 4690 24 and and CC cord-022526-j9kg00qf 4690 25 bleeding bleeding NN cord-022526-j9kg00qf 4690 26 ( ( -LRB- cord-022526-j9kg00qf 4690 27 if if IN cord-022526-j9kg00qf 4690 28 an an DT cord-022526-j9kg00qf 4690 29 enterotomy enterotomy NN cord-022526-j9kg00qf 4690 30 has have VBZ cord-022526-j9kg00qf 4690 31 been be VBN cord-022526-j9kg00qf 4690 32 performed perform VBN cord-022526-j9kg00qf 4690 33 ) ) -RRB- cord-022526-j9kg00qf 4690 34 , , , cord-022526-j9kg00qf 4690 35 palpation palpation NN cord-022526-j9kg00qf 4690 36 of of IN cord-022526-j9kg00qf 4690 37 a a DT cord-022526-j9kg00qf 4690 38 pulse pulse NN cord-022526-j9kg00qf 4690 39 in in IN cord-022526-j9kg00qf 4690 40 the the DT cord-022526-j9kg00qf 4690 41 colonic colonic JJ cord-022526-j9kg00qf 4690 42 arteries artery NNS cord-022526-j9kg00qf 4690 43 , , , cord-022526-j9kg00qf 4690 44 serosal serosal NN cord-022526-j9kg00qf 4690 45 color color NN cord-022526-j9kg00qf 4690 46 , , , cord-022526-j9kg00qf 4690 47 and and CC cord-022526-j9kg00qf 4690 48 appearance appearance NN cord-022526-j9kg00qf 4690 49 of of IN cord-022526-j9kg00qf 4690 50 muscular muscular JJ cord-022526-j9kg00qf 4690 51 motility motility NN cord-022526-j9kg00qf 4690 52 . . . cord-022526-j9kg00qf 4691 1 If if IN cord-022526-j9kg00qf 4691 2 one one CD cord-022526-j9kg00qf 4691 3 judges judge VBZ cord-022526-j9kg00qf 4691 4 the the DT cord-022526-j9kg00qf 4691 5 colon colon NN cord-022526-j9kg00qf 4691 6 to to TO cord-022526-j9kg00qf 4691 7 be be VB cord-022526-j9kg00qf 4691 8 damaged damage VBN cord-022526-j9kg00qf 4691 9 irreversibly irreversibly RB cord-022526-j9kg00qf 4691 10 , , , cord-022526-j9kg00qf 4691 11 one one PRP cord-022526-j9kg00qf 4691 12 can can MD cord-022526-j9kg00qf 4691 13 consider consider VB cord-022526-j9kg00qf 4691 14 the the DT cord-022526-j9kg00qf 4691 15 feasibility feasibility NN cord-022526-j9kg00qf 4691 16 of of IN cord-022526-j9kg00qf 4691 17 a a DT cord-022526-j9kg00qf 4691 18 large large JJ cord-022526-j9kg00qf 4691 19 colon colon NN cord-022526-j9kg00qf 4691 20 resection resection NN cord-022526-j9kg00qf 4691 21 . . . cord-022526-j9kg00qf 4692 1 Although although IN cord-022526-j9kg00qf 4692 2 95 95 CD cord-022526-j9kg00qf 4692 3 % % NN cord-022526-j9kg00qf 4692 4 of of IN cord-022526-j9kg00qf 4692 5 the the DT cord-022526-j9kg00qf 4692 6 colon colon NN cord-022526-j9kg00qf 4692 7 can can MD cord-022526-j9kg00qf 4692 8 be be VB cord-022526-j9kg00qf 4692 9 resected resect VBN cord-022526-j9kg00qf 4692 10 ( ( -LRB- cord-022526-j9kg00qf 4692 11 that that DT cord-022526-j9kg00qf 4692 12 part part NN cord-022526-j9kg00qf 4692 13 of of IN cord-022526-j9kg00qf 4692 14 the the DT cord-022526-j9kg00qf 4692 15 colon colon NN cord-022526-j9kg00qf 4692 16 distal distal IN cord-022526-j9kg00qf 4692 17 to to IN cord-022526-j9kg00qf 4692 18 the the DT cord-022526-j9kg00qf 4692 19 level level NN cord-022526-j9kg00qf 4692 20 of of IN cord-022526-j9kg00qf 4692 21 the the DT cord-022526-j9kg00qf 4692 22 cecocolic cecocolic JJ cord-022526-j9kg00qf 4692 23 fold fold NN cord-022526-j9kg00qf 4692 24 ) ) -RRB- cord-022526-j9kg00qf 4692 25 , , , cord-022526-j9kg00qf 4692 26 damage damage NN cord-022526-j9kg00qf 4692 27 from from IN cord-022526-j9kg00qf 4692 28 the the DT cord-022526-j9kg00qf 4692 29 volvulus volvulus NN cord-022526-j9kg00qf 4692 30 usually usually RB cord-022526-j9kg00qf 4692 31 exceeds exceed VBZ cord-022526-j9kg00qf 4692 32 that that IN cord-022526-j9kg00qf 4692 33 which which WDT cord-022526-j9kg00qf 4692 34 can can MD cord-022526-j9kg00qf 4692 35 be be VB cord-022526-j9kg00qf 4692 36 resected resect VBN cord-022526-j9kg00qf 4692 37 . . . cord-022526-j9kg00qf 4693 1 In in IN cord-022526-j9kg00qf 4693 2 these these DT cord-022526-j9kg00qf 4693 3 cases case NNS cord-022526-j9kg00qf 4693 4 , , , cord-022526-j9kg00qf 4693 5 surgeons surgeon NNS cord-022526-j9kg00qf 4693 6 may may MD cord-022526-j9kg00qf 4693 7 elect elect VB cord-022526-j9kg00qf 4693 8 to to TO cord-022526-j9kg00qf 4693 9 resect resect VB cord-022526-j9kg00qf 4693 10 as as RB cord-022526-j9kg00qf 4693 11 much much JJ cord-022526-j9kg00qf 4693 12 damaged damage VBN cord-022526-j9kg00qf 4693 13 bowel bowel NN cord-022526-j9kg00qf 4693 14 as as IN cord-022526-j9kg00qf 4693 15 possible possible JJ cord-022526-j9kg00qf 4693 16 or or CC cord-022526-j9kg00qf 4693 17 may may MD cord-022526-j9kg00qf 4693 18 advise advise VB cord-022526-j9kg00qf 4693 19 euthanasia euthanasia NN cord-022526-j9kg00qf 4693 20 . . . cord-022526-j9kg00qf 4694 1 7 7 CD cord-022526-j9kg00qf 4695 1 The the DT cord-022526-j9kg00qf 4695 2 prognosis prognosis NN cord-022526-j9kg00qf 4695 3 is be VBZ cord-022526-j9kg00qf 4695 4 guarded guard VBN cord-022526-j9kg00qf 4695 5 to to IN cord-022526-j9kg00qf 4695 6 poor poor JJ cord-022526-j9kg00qf 4695 7 because because IN cord-022526-j9kg00qf 4695 8 of of IN cord-022526-j9kg00qf 4695 9 the the DT cord-022526-j9kg00qf 4695 10 rapid rapid JJ cord-022526-j9kg00qf 4695 11 onset onset NN cord-022526-j9kg00qf 4695 12 of of IN cord-022526-j9kg00qf 4695 13 this this DT cord-022526-j9kg00qf 4695 14 disease disease NN cord-022526-j9kg00qf 4695 15 . . . cord-022526-j9kg00qf 4696 1 In in IN cord-022526-j9kg00qf 4696 2 one one CD cord-022526-j9kg00qf 4696 3 study study NN cord-022526-j9kg00qf 4696 4 the the DT cord-022526-j9kg00qf 4696 5 survival survival NN cord-022526-j9kg00qf 4696 6 rate rate NN cord-022526-j9kg00qf 4696 7 was be VBD cord-022526-j9kg00qf 4696 8 35 35 CD cord-022526-j9kg00qf 4696 9 % % NN cord-022526-j9kg00qf 4696 10 . . . cord-022526-j9kg00qf 4697 1 58 58 CD cord-022526-j9kg00qf 4698 1 In in IN cord-022526-j9kg00qf 4698 2 a a DT cord-022526-j9kg00qf 4698 3 more more RBR cord-022526-j9kg00qf 4698 4 recent recent JJ cord-022526-j9kg00qf 4698 5 report report NN cord-022526-j9kg00qf 4698 6 the the DT cord-022526-j9kg00qf 4698 7 survival survival NN cord-022526-j9kg00qf 4698 8 rate rate NN cord-022526-j9kg00qf 4698 9 was be VBD cord-022526-j9kg00qf 4698 10 36 36 CD cord-022526-j9kg00qf 4698 11 % % NN cord-022526-j9kg00qf 4698 12 for for IN cord-022526-j9kg00qf 4698 13 horses horse NNS cord-022526-j9kg00qf 4698 14 with with IN cord-022526-j9kg00qf 4698 15 360-degree 360-degree CD cord-022526-j9kg00qf 4698 16 volvulus volvulus NN cord-022526-j9kg00qf 4698 17 of of IN cord-022526-j9kg00qf 4698 18 the the DT cord-022526-j9kg00qf 4698 19 large large JJ cord-022526-j9kg00qf 4698 20 colon colon NN cord-022526-j9kg00qf 4698 21 compared compare VBN cord-022526-j9kg00qf 4698 22 with with IN cord-022526-j9kg00qf 4698 23 71 71 CD cord-022526-j9kg00qf 4698 24 % % NN cord-022526-j9kg00qf 4698 25 for for IN cord-022526-j9kg00qf 4698 26 horses horse NNS cord-022526-j9kg00qf 4698 27 with with IN cord-022526-j9kg00qf 4698 28 270-degree 270-degree CD cord-022526-j9kg00qf 4698 29 volvulus volvulus NN cord-022526-j9kg00qf 4698 30 . . . cord-022526-j9kg00qf 4699 1 4 4 LS cord-022526-j9kg00qf 4700 1 However however RB cord-022526-j9kg00qf 4700 2 , , , cord-022526-j9kg00qf 4700 3 one one CD cord-022526-j9kg00qf 4700 4 study study NN cord-022526-j9kg00qf 4700 5 in in IN cord-022526-j9kg00qf 4700 6 central central JJ cord-022526-j9kg00qf 4700 7 Kentucky Kentucky NNP cord-022526-j9kg00qf 4700 8 documented document VBD cord-022526-j9kg00qf 4700 9 a a DT cord-022526-j9kg00qf 4700 10 high high JJ cord-022526-j9kg00qf 4700 11 success success NN cord-022526-j9kg00qf 4700 12 rate rate NN cord-022526-j9kg00qf 4700 13 , , , cord-022526-j9kg00qf 4700 14 possibly possibly RB cord-022526-j9kg00qf 4700 15 because because IN cord-022526-j9kg00qf 4700 16 of of IN cord-022526-j9kg00qf 4700 17 early early JJ cord-022526-j9kg00qf 4700 18 recognition recognition NN cord-022526-j9kg00qf 4700 19 of of IN cord-022526-j9kg00qf 4700 20 the the DT cord-022526-j9kg00qf 4700 21 disease disease NN cord-022526-j9kg00qf 4700 22 and and CC cord-022526-j9kg00qf 4700 23 the the DT cord-022526-j9kg00qf 4700 24 proximity proximity NN cord-022526-j9kg00qf 4700 25 of of IN cord-022526-j9kg00qf 4700 26 the the DT cord-022526-j9kg00qf 4700 27 hospital hospital NN cord-022526-j9kg00qf 4700 28 to to IN cord-022526-j9kg00qf 4700 29 the the DT cord-022526-j9kg00qf 4700 30 surgical surgical JJ cord-022526-j9kg00qf 4700 31 caseload caseload NN cord-022526-j9kg00qf 4700 32 . . . cord-022526-j9kg00qf 4701 1 60 60 CD cord-022526-j9kg00qf 4701 2 Postoperative postoperative JJ cord-022526-j9kg00qf 4701 3 complications complication NNS cord-022526-j9kg00qf 4701 4 include include VBP cord-022526-j9kg00qf 4701 5 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 4701 6 and and CC cord-022526-j9kg00qf 4701 7 endotoxic endotoxic JJ cord-022526-j9kg00qf 4701 8 shock shock NN cord-022526-j9kg00qf 4701 9 , , , cord-022526-j9kg00qf 4701 10 extensive extensive JJ cord-022526-j9kg00qf 4701 11 loss loss NN cord-022526-j9kg00qf 4701 12 of of IN cord-022526-j9kg00qf 4701 13 circulating circulate VBG cord-022526-j9kg00qf 4701 14 protein protein NN cord-022526-j9kg00qf 4701 15 , , , cord-022526-j9kg00qf 4701 16 disseminated disseminate VBN cord-022526-j9kg00qf 4701 17 intravascular intravascular JJ cord-022526-j9kg00qf 4701 18 coagulation coagulation NN cord-022526-j9kg00qf 4701 19 , , , cord-022526-j9kg00qf 4701 20 and and CC cord-022526-j9kg00qf 4701 21 laminitis laminitis NN cord-022526-j9kg00qf 4701 22 . . . cord-022526-j9kg00qf 4702 1 In in IN cord-022526-j9kg00qf 4702 2 addition addition NN cord-022526-j9kg00qf 4702 3 , , , cord-022526-j9kg00qf 4702 4 large large JJ cord-022526-j9kg00qf 4702 5 colon colon NN cord-022526-j9kg00qf 4702 6 volvulus volvulus NN cord-022526-j9kg00qf 4702 7 has have VBZ cord-022526-j9kg00qf 4702 8 a a DT cord-022526-j9kg00qf 4702 9 propensity propensity NN cord-022526-j9kg00qf 4702 10 to to TO cord-022526-j9kg00qf 4702 11 recur recur VB cord-022526-j9kg00qf 4702 12 . . . cord-022526-j9kg00qf 4703 1 Although although IN cord-022526-j9kg00qf 4703 2 one one CD cord-022526-j9kg00qf 4703 3 study study NN cord-022526-j9kg00qf 4703 4 documented document VBD cord-022526-j9kg00qf 4703 5 a a DT cord-022526-j9kg00qf 4703 6 recurrence recurrence NN cord-022526-j9kg00qf 4703 7 rate rate NN cord-022526-j9kg00qf 4703 8 of of IN cord-022526-j9kg00qf 4703 9 less less JJR cord-022526-j9kg00qf 4703 10 than than IN cord-022526-j9kg00qf 4703 11 5 5 CD cord-022526-j9kg00qf 4703 12 % % NN cord-022526-j9kg00qf 4703 13 , , , cord-022526-j9kg00qf 4703 14 58 58 CD cord-022526-j9kg00qf 4704 1 some some DT cord-022526-j9kg00qf 4704 2 authors author NNS cord-022526-j9kg00qf 4704 3 believe believe VBP cord-022526-j9kg00qf 4704 4 recurrence recurrence NN cord-022526-j9kg00qf 4704 5 may may MD cord-022526-j9kg00qf 4704 6 be be VB cord-022526-j9kg00qf 4704 7 as as RB cord-022526-j9kg00qf 4704 8 high high JJ cord-022526-j9kg00qf 4704 9 as as IN cord-022526-j9kg00qf 4704 10 50 50 CD cord-022526-j9kg00qf 4704 11 % % NN cord-022526-j9kg00qf 4704 12 . . . cord-022526-j9kg00qf 4705 1 7 7 CD cord-022526-j9kg00qf 4706 1 Therefore therefore RB cord-022526-j9kg00qf 4706 2 one one PRP cord-022526-j9kg00qf 4706 3 should should MD cord-022526-j9kg00qf 4706 4 consider consider VB cord-022526-j9kg00qf 4706 5 methods method NNS cord-022526-j9kg00qf 4706 6 to to TO cord-022526-j9kg00qf 4706 7 prevent prevent VB cord-022526-j9kg00qf 4706 8 recurrence recurrence NN cord-022526-j9kg00qf 4706 9 in in IN cord-022526-j9kg00qf 4706 10 patients patient NNS cord-022526-j9kg00qf 4706 11 at at IN cord-022526-j9kg00qf 4706 12 risk risk NN cord-022526-j9kg00qf 4706 13 of of IN cord-022526-j9kg00qf 4706 14 recurrence recurrence NN cord-022526-j9kg00qf 4706 15 , , , cord-022526-j9kg00qf 4706 16 particularly particularly RB cord-022526-j9kg00qf 4706 17 broodmares broodmare NNS cord-022526-j9kg00qf 4706 18 that that WDT cord-022526-j9kg00qf 4706 19 tend tend VBP cord-022526-j9kg00qf 4706 20 to to TO cord-022526-j9kg00qf 4706 21 suffer suffer VB cord-022526-j9kg00qf 4706 22 from from IN cord-022526-j9kg00qf 4706 23 the the DT cord-022526-j9kg00qf 4706 24 disease disease NN cord-022526-j9kg00qf 4706 25 recurrently recurrently RB cord-022526-j9kg00qf 4706 26 during during IN cord-022526-j9kg00qf 4706 27 the the DT cord-022526-j9kg00qf 4706 28 foaling foaling NN cord-022526-j9kg00qf 4706 29 season season NN cord-022526-j9kg00qf 4706 30 . . . cord-022526-j9kg00qf 4707 1 61 61 CD cord-022526-j9kg00qf 4707 2 , , , cord-022526-j9kg00qf 4707 3 62 62 CD cord-022526-j9kg00qf 4707 4 _SP cord-022526-j9kg00qf 4708 1 The the DT cord-022526-j9kg00qf 4708 2 most most RBS cord-022526-j9kg00qf 4708 3 common common JJ cord-022526-j9kg00qf 4708 4 intussusceptions intussusception NNS cord-022526-j9kg00qf 4708 5 of of IN cord-022526-j9kg00qf 4708 6 the the DT cord-022526-j9kg00qf 4708 7 large large JJ cord-022526-j9kg00qf 4708 8 intestine intestine NN cord-022526-j9kg00qf 4708 9 are be VBP cord-022526-j9kg00qf 4708 10 cecocecal cecocecal JJ cord-022526-j9kg00qf 4708 11 and and CC cord-022526-j9kg00qf 4708 12 cecocolic cecocolic JJ cord-022526-j9kg00qf 4708 13 intussusceptions intussusception NNS cord-022526-j9kg00qf 4708 14 . . . cord-022526-j9kg00qf 4709 1 63 63 CD cord-022526-j9kg00qf 4709 2 , , , cord-022526-j9kg00qf 4709 3 64 64 CD cord-022526-j9kg00qf 4709 4 Both both DT cord-022526-j9kg00qf 4709 5 are be VBP cord-022526-j9kg00qf 4709 6 likely likely RB cord-022526-j9kg00qf 4709 7 attributable attributable JJ cord-022526-j9kg00qf 4709 8 to to IN cord-022526-j9kg00qf 4709 9 the the DT cord-022526-j9kg00qf 4709 10 same same JJ cord-022526-j9kg00qf 4709 11 disease disease NN cord-022526-j9kg00qf 4709 12 process process NN cord-022526-j9kg00qf 4709 13 , , , cord-022526-j9kg00qf 4709 14 with with IN cord-022526-j9kg00qf 4709 15 variable variable JJ cord-022526-j9kg00qf 4709 16 inversion inversion NN cord-022526-j9kg00qf 4709 17 of of IN cord-022526-j9kg00qf 4709 18 the the DT cord-022526-j9kg00qf 4709 19 cecum cecum NN cord-022526-j9kg00qf 4709 20 . . . cord-022526-j9kg00qf 4710 1 These these DT cord-022526-j9kg00qf 4710 2 conditions condition NNS cord-022526-j9kg00qf 4710 3 doughnut doughnut NN cord-022526-j9kg00qf 4710 4 - - HYPH cord-022526-j9kg00qf 4710 5 shaped shape VBN cord-022526-j9kg00qf 4710 6 prolapse prolapse NN cord-022526-j9kg00qf 4710 7 of of IN cord-022526-j9kg00qf 4710 8 rectal rectal JJ cord-022526-j9kg00qf 4710 9 mucosa mucosa NN cord-022526-j9kg00qf 4710 10 and and CC cord-022526-j9kg00qf 4710 11 submucosa submucosa NNP cord-022526-j9kg00qf 4710 12 . . . cord-022526-j9kg00qf 4711 1 Type type NN cord-022526-j9kg00qf 4711 2 II II NNP cord-022526-j9kg00qf 4711 3 prolapses prolapse NNS cord-022526-j9kg00qf 4711 4 involve involve VBP cord-022526-j9kg00qf 4711 5 full full JJ cord-022526-j9kg00qf 4711 6 - - HYPH cord-022526-j9kg00qf 4711 7 thickness thickness NN cord-022526-j9kg00qf 4711 8 rectal rectal JJ cord-022526-j9kg00qf 4711 9 tissue tissue NN cord-022526-j9kg00qf 4711 10 , , , cord-022526-j9kg00qf 4711 11 whereas whereas IN cord-022526-j9kg00qf 4711 12 type type NN cord-022526-j9kg00qf 4711 13 III iii CD cord-022526-j9kg00qf 4711 14 prolapses prolapse NNS cord-022526-j9kg00qf 4711 15 additionally additionally RB cord-022526-j9kg00qf 4711 16 have have VBP cord-022526-j9kg00qf 4711 17 invagination invagination NN cord-022526-j9kg00qf 4711 18 of of IN cord-022526-j9kg00qf 4711 19 small small JJ cord-022526-j9kg00qf 4711 20 colon colon NN cord-022526-j9kg00qf 4711 21 into into IN cord-022526-j9kg00qf 4711 22 the the DT cord-022526-j9kg00qf 4711 23 rectum rectum NN cord-022526-j9kg00qf 4711 24 . . . cord-022526-j9kg00qf 4712 1 Type type NN cord-022526-j9kg00qf 4712 2 IV IV NNP cord-022526-j9kg00qf 4712 3 prolapses prolapse NNS cord-022526-j9kg00qf 4712 4 involve involve VBP cord-022526-j9kg00qf 4712 5 intussusception intussusception NN cord-022526-j9kg00qf 4712 6 of of IN cord-022526-j9kg00qf 4712 7 proximal proximal JJ cord-022526-j9kg00qf 4712 8 rectum rectum NN cord-022526-j9kg00qf 4712 9 or or CC cord-022526-j9kg00qf 4712 10 small small JJ cord-022526-j9kg00qf 4712 11 colon colon NN cord-022526-j9kg00qf 4712 12 through through IN cord-022526-j9kg00qf 4712 13 the the DT cord-022526-j9kg00qf 4712 14 anus anus NN cord-022526-j9kg00qf 4712 15 in in IN cord-022526-j9kg00qf 4712 16 the the DT cord-022526-j9kg00qf 4712 17 absence absence NN cord-022526-j9kg00qf 4712 18 of of IN cord-022526-j9kg00qf 4712 19 prolapse prolapse NN cord-022526-j9kg00qf 4712 20 of of IN cord-022526-j9kg00qf 4712 21 tissue tissue NN cord-022526-j9kg00qf 4712 22 at at IN cord-022526-j9kg00qf 4712 23 the the DT cord-022526-j9kg00qf 4712 24 mucocutaneous mucocutaneous JJ cord-022526-j9kg00qf 4712 25 junction junction NNP cord-022526-j9kg00qf 4712 26 at at IN cord-022526-j9kg00qf 4712 27 the the DT cord-022526-j9kg00qf 4712 28 anus anus NN cord-022526-j9kg00qf 4712 29 . . . cord-022526-j9kg00qf 4713 1 73 73 CD cord-022526-j9kg00qf 4714 1 One one PRP cord-022526-j9kg00qf 4714 2 can can MD cord-022526-j9kg00qf 4714 3 differentiate differentiate VB cord-022526-j9kg00qf 4714 4 type type NN cord-022526-j9kg00qf 4714 5 IV IV NNP cord-022526-j9kg00qf 4714 6 from from IN cord-022526-j9kg00qf 4714 7 other other JJ cord-022526-j9kg00qf 4714 8 forms form NNS cord-022526-j9kg00qf 4714 9 of of IN cord-022526-j9kg00qf 4714 10 prolapse prolapse NN cord-022526-j9kg00qf 4714 11 by by IN cord-022526-j9kg00qf 4714 12 their -PRON- PRP$ cord-022526-j9kg00qf 4714 13 appearance appearance NN cord-022526-j9kg00qf 4714 14 and and CC cord-022526-j9kg00qf 4714 15 a a DT cord-022526-j9kg00qf 4714 16 palpable palpable JJ cord-022526-j9kg00qf 4714 17 trench trench NN cord-022526-j9kg00qf 4714 18 between between IN cord-022526-j9kg00qf 4714 19 prolapsed prolapsed JJ cord-022526-j9kg00qf 4714 20 tissue tissue NN cord-022526-j9kg00qf 4714 21 and and CC cord-022526-j9kg00qf 4714 22 the the DT cord-022526-j9kg00qf 4714 23 anus anus NN cord-022526-j9kg00qf 4714 24 . . . cord-022526-j9kg00qf 4715 1 Type type NN cord-022526-j9kg00qf 4716 1 I -PRON- PRP cord-022526-j9kg00qf 4716 2 prolapses prolapse NNS cord-022526-j9kg00qf 4716 3 occur occur VBP cord-022526-j9kg00qf 4716 4 most most RBS cord-022526-j9kg00qf 4716 5 frequently frequently RB cord-022526-j9kg00qf 4716 6 in in IN cord-022526-j9kg00qf 4716 7 horses horse NNS cord-022526-j9kg00qf 4716 8 with with IN cord-022526-j9kg00qf 4716 9 diarrhea diarrhea NN cord-022526-j9kg00qf 4716 10 , , , cord-022526-j9kg00qf 4716 11 in in IN cord-022526-j9kg00qf 4716 12 which which WDT cord-022526-j9kg00qf 4716 13 the the DT cord-022526-j9kg00qf 4716 14 rectal rectal JJ cord-022526-j9kg00qf 4716 15 mucosa mucosa NN cord-022526-j9kg00qf 4716 16 becomes become VBZ cord-022526-j9kg00qf 4716 17 irritated irritated JJ cord-022526-j9kg00qf 4716 18 and and CC cord-022526-j9kg00qf 4716 19 protrudes protrude VBZ cord-022526-j9kg00qf 4716 20 intermittently intermittently RB cord-022526-j9kg00qf 4716 21 during during IN cord-022526-j9kg00qf 4716 22 episodes episode NNS cord-022526-j9kg00qf 4716 23 of of IN cord-022526-j9kg00qf 4716 24 tenesmus tenesmus NNP cord-022526-j9kg00qf 4716 25 . . . cord-022526-j9kg00qf 4717 1 If if IN cord-022526-j9kg00qf 4717 2 tenesmus tenesmus NNP cord-022526-j9kg00qf 4717 3 persists persist VBZ cord-022526-j9kg00qf 4717 4 , , , cord-022526-j9kg00qf 4717 5 rectal rectal JJ cord-022526-j9kg00qf 4717 6 mucosa mucosa NN cord-022526-j9kg00qf 4717 7 can can MD cord-022526-j9kg00qf 4717 8 remain remain VB cord-022526-j9kg00qf 4717 9 prolapsed prolapsed JJ cord-022526-j9kg00qf 4717 10 . . . cord-022526-j9kg00qf 4718 1 Rectal rectal JJ cord-022526-j9kg00qf 4718 2 mucosa mucosa NN cord-022526-j9kg00qf 4718 3 rapidly rapidly RB cord-022526-j9kg00qf 4718 4 becomes become VBZ cord-022526-j9kg00qf 4718 5 congested congested JJ cord-022526-j9kg00qf 4718 6 and and CC cord-022526-j9kg00qf 4718 7 edematous edematous JJ cord-022526-j9kg00qf 4718 8 under under IN cord-022526-j9kg00qf 4718 9 these these DT cord-022526-j9kg00qf 4718 10 conditions condition NNS cord-022526-j9kg00qf 4718 11 , , , cord-022526-j9kg00qf 4718 12 which which WDT cord-022526-j9kg00qf 4718 13 one one PRP cord-022526-j9kg00qf 4718 14 should should MD cord-022526-j9kg00qf 4718 15 treat treat VB cord-022526-j9kg00qf 4718 16 with with IN cord-022526-j9kg00qf 4718 17 osmotic osmotic JJ cord-022526-j9kg00qf 4718 18 agents agent NNS cord-022526-j9kg00qf 4718 19 such such JJ cord-022526-j9kg00qf 4718 20 as as IN cord-022526-j9kg00qf 4718 21 glycerin glycerin NN cord-022526-j9kg00qf 4718 22 or or CC cord-022526-j9kg00qf 4718 23 magnesium magnesium NN cord-022526-j9kg00qf 4718 24 sulfate sulfate NN cord-022526-j9kg00qf 4718 25 and and CC cord-022526-j9kg00qf 4718 26 by by IN cord-022526-j9kg00qf 4718 27 massaging massage VBG cord-022526-j9kg00qf 4718 28 and and CC cord-022526-j9kg00qf 4718 29 reducing reduce VBG cord-022526-j9kg00qf 4718 30 the the DT cord-022526-j9kg00qf 4718 31 prolapse prolapse NN cord-022526-j9kg00qf 4718 32 . . . cord-022526-j9kg00qf 4719 1 74 74 CD cord-022526-j9kg00qf 4720 1 A a DT cord-022526-j9kg00qf 4720 2 purse purse NN cord-022526-j9kg00qf 4720 3 - - HYPH cord-022526-j9kg00qf 4720 4 string string NN cord-022526-j9kg00qf 4720 5 suture suture NN cord-022526-j9kg00qf 4720 6 may may MD cord-022526-j9kg00qf 4720 7 be be VB cord-022526-j9kg00qf 4720 8 required require VBN cord-022526-j9kg00qf 4720 9 to to TO cord-022526-j9kg00qf 4720 10 keep keep VB cord-022526-j9kg00qf 4720 11 the the DT cord-022526-j9kg00qf 4720 12 mucosa mucosa NN cord-022526-j9kg00qf 4720 13 inside inside IN cord-022526-j9kg00qf 4720 14 the the DT cord-022526-j9kg00qf 4720 15 rectum rectum NN cord-022526-j9kg00qf 4720 16 . . . cord-022526-j9kg00qf 4721 1 Topical topical JJ cord-022526-j9kg00qf 4721 2 application application NN cord-022526-j9kg00qf 4721 3 of of IN cord-022526-j9kg00qf 4721 4 lidocaine lidocaine NN cord-022526-j9kg00qf 4721 5 solution solution NN cord-022526-j9kg00qf 4721 6 or or CC cord-022526-j9kg00qf 4721 7 jelly jelly NN cord-022526-j9kg00qf 4721 8 , , , cord-022526-j9kg00qf 4721 9 epidural epidural NN cord-022526-j9kg00qf 4721 10 anesthesia anesthesia NN cord-022526-j9kg00qf 4721 11 , , , cord-022526-j9kg00qf 4721 12 and and CC cord-022526-j9kg00qf 4721 13 sedation sedation NN cord-022526-j9kg00qf 4721 14 may may MD cord-022526-j9kg00qf 4721 15 help help VB cord-022526-j9kg00qf 4721 16 reduce reduce VB cord-022526-j9kg00qf 4721 17 tenesmus tenesmus NN cord-022526-j9kg00qf 4721 18 that that WDT cord-022526-j9kg00qf 4721 19 incites incite VBZ cord-022526-j9kg00qf 4721 20 and and CC cord-022526-j9kg00qf 4721 21 exacerbates exacerbate VBZ cord-022526-j9kg00qf 4721 22 rectal rectal JJ cord-022526-j9kg00qf 4721 23 prolapse prolapse NN cord-022526-j9kg00qf 4721 24 . . . cord-022526-j9kg00qf 4722 1 One one PRP cord-022526-j9kg00qf 4722 2 can can MD cord-022526-j9kg00qf 4722 3 apply apply VB cord-022526-j9kg00qf 4722 4 similar similar JJ cord-022526-j9kg00qf 4722 5 treatments treatment NNS cord-022526-j9kg00qf 4722 6 to to TO cord-022526-j9kg00qf 4722 7 type type VB cord-022526-j9kg00qf 4722 8 II ii CD cord-022526-j9kg00qf 4722 9 rectal rectal JJ cord-022526-j9kg00qf 4722 10 prolapses prolapse NNS cord-022526-j9kg00qf 4722 11 . . . cord-022526-j9kg00qf 4723 1 However however RB cord-022526-j9kg00qf 4723 2 , , , cord-022526-j9kg00qf 4723 3 these these DT cord-022526-j9kg00qf 4723 4 more more RBR cord-022526-j9kg00qf 4723 5 severe severe JJ cord-022526-j9kg00qf 4723 6 prolapses prolapse NNS cord-022526-j9kg00qf 4723 7 may may MD cord-022526-j9kg00qf 4723 8 not not RB cord-022526-j9kg00qf 4723 9 be be VB cord-022526-j9kg00qf 4723 10 reducible reducible JJ cord-022526-j9kg00qf 4723 11 without without IN cord-022526-j9kg00qf 4723 12 surgical surgical JJ cord-022526-j9kg00qf 4723 13 resection resection NN cord-022526-j9kg00qf 4723 14 of of IN cord-022526-j9kg00qf 4723 15 mucosa mucosa JJ cord-022526-j9kg00qf 4723 16 and and CC cord-022526-j9kg00qf 4723 17 submucosa submucosa NNPS cord-022526-j9kg00qf 4723 18 from from IN cord-022526-j9kg00qf 4723 19 the the DT cord-022526-j9kg00qf 4723 20 prolapsed prolapsed JJ cord-022526-j9kg00qf 4723 21 bowel bowel NN cord-022526-j9kg00qf 4723 22 . . . cord-022526-j9kg00qf 4724 1 70 70 CD cord-022526-j9kg00qf 4724 2 , , , cord-022526-j9kg00qf 4724 3 74 74 CD cord-022526-j9kg00qf 4724 4 Type Type NNP cord-022526-j9kg00qf 4724 5 III III NNP cord-022526-j9kg00qf 4724 6 and and CC cord-022526-j9kg00qf 4724 7 IV IV NNP cord-022526-j9kg00qf 4724 8 rectal rectal JJ cord-022526-j9kg00qf 4724 9 prolapses prolapse NNS cord-022526-j9kg00qf 4724 10 are be VBP cord-022526-j9kg00qf 4724 11 more more RBR cord-022526-j9kg00qf 4724 12 serious serious JJ cord-022526-j9kg00qf 4724 13 injuries injury NNS cord-022526-j9kg00qf 4724 14 because because IN cord-022526-j9kg00qf 4724 15 of of IN cord-022526-j9kg00qf 4724 16 involvement involvement NN cord-022526-j9kg00qf 4724 17 of of IN cord-022526-j9kg00qf 4724 18 small small JJ cord-022526-j9kg00qf 4724 19 colon colon NN cord-022526-j9kg00qf 4724 20 . . . cord-022526-j9kg00qf 4725 1 75 75 CD cord-022526-j9kg00qf 4726 1 In in IN cord-022526-j9kg00qf 4726 2 horses horse NNS cord-022526-j9kg00qf 4726 3 with with IN cord-022526-j9kg00qf 4726 4 type type NN cord-022526-j9kg00qf 4726 5 III iii CD cord-022526-j9kg00qf 4726 6 prolapses prolapse NNS cord-022526-j9kg00qf 4726 7 , , , cord-022526-j9kg00qf 4726 8 one one PRP cord-022526-j9kg00qf 4726 9 should should MD cord-022526-j9kg00qf 4726 10 perform perform VB cord-022526-j9kg00qf 4726 11 an an DT cord-022526-j9kg00qf 4726 12 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4726 13 to to TO cord-022526-j9kg00qf 4726 14 determine determine VB cord-022526-j9kg00qf 4726 15 if if IN cord-022526-j9kg00qf 4726 16 injured injure VBN cord-022526-j9kg00qf 4726 17 small small JJ cord-022526-j9kg00qf 4726 18 colon colon NN cord-022526-j9kg00qf 4726 19 has have VBZ cord-022526-j9kg00qf 4726 20 resulted result VBN cord-022526-j9kg00qf 4726 21 in in IN cord-022526-j9kg00qf 4726 22 peritonitis peritonitis NN cord-022526-j9kg00qf 4726 23 . . . cord-022526-j9kg00qf 4727 1 One one PRP cord-022526-j9kg00qf 4727 2 should should MD cord-022526-j9kg00qf 4727 3 reduce reduce VB cord-022526-j9kg00qf 4727 4 the the DT cord-022526-j9kg00qf 4727 5 small small JJ cord-022526-j9kg00qf 4727 6 colon colon NN cord-022526-j9kg00qf 4727 7 component component NN cord-022526-j9kg00qf 4727 8 manually manually RB cord-022526-j9kg00qf 4727 9 if if IN cord-022526-j9kg00qf 4727 10 possible possible JJ cord-022526-j9kg00qf 4727 11 , , , cord-022526-j9kg00qf 4727 12 although although IN cord-022526-j9kg00qf 4727 13 prolapsed prolapsed JJ cord-022526-j9kg00qf 4727 14 rectal rectal JJ cord-022526-j9kg00qf 4727 15 tissue tissue NN cord-022526-j9kg00qf 4727 16 typically typically RB cord-022526-j9kg00qf 4727 17 requires require VBZ cord-022526-j9kg00qf 4727 18 mucosal/ mucosal/ NNS cord-022526-j9kg00qf 4727 19 submucosal submucosal NNP cord-022526-j9kg00qf 4727 20 resection resection NN cord-022526-j9kg00qf 4727 21 . . . cord-022526-j9kg00qf 4728 1 One one PRP cord-022526-j9kg00qf 4728 2 should should MD cord-022526-j9kg00qf 4728 3 perform perform VB cord-022526-j9kg00qf 4728 4 surgical surgical JJ cord-022526-j9kg00qf 4728 5 exploration exploration NN cord-022526-j9kg00qf 4728 6 of of IN cord-022526-j9kg00qf 4728 7 the the DT cord-022526-j9kg00qf 4728 8 abdomen abdomen NN cord-022526-j9kg00qf 4728 9 to to TO cord-022526-j9kg00qf 4728 10 determine determine VB cord-022526-j9kg00qf 4728 11 the the DT cord-022526-j9kg00qf 4728 12 status status NN cord-022526-j9kg00qf 4728 13 of of IN cord-022526-j9kg00qf 4728 14 the the DT cord-022526-j9kg00qf 4728 15 small small JJ cord-022526-j9kg00qf 4728 16 colon colon NN cord-022526-j9kg00qf 4728 17 , , , cord-022526-j9kg00qf 4728 18 although although IN cord-022526-j9kg00qf 4728 19 one one PRP cord-022526-j9kg00qf 4728 20 can can MD cord-022526-j9kg00qf 4728 21 use use VB cord-022526-j9kg00qf 4728 22 serial serial JJ cord-022526-j9kg00qf 4728 23 abdominocenteses abdominocentese NNS cord-022526-j9kg00qf 4728 24 in in IN cord-022526-j9kg00qf 4728 25 lieu lieu NN cord-022526-j9kg00qf 4728 26 of of IN cord-022526-j9kg00qf 4728 27 surgery surgery NN cord-022526-j9kg00qf 4728 28 to to TO cord-022526-j9kg00qf 4728 29 detect detect VB cord-022526-j9kg00qf 4728 30 progressive progressive JJ cord-022526-j9kg00qf 4728 31 necrosis necrosis NN cord-022526-j9kg00qf 4728 32 of of IN cord-022526-j9kg00qf 4728 33 bowel bowel NN cord-022526-j9kg00qf 4728 34 . . . cord-022526-j9kg00qf 4729 1 Type type NN cord-022526-j9kg00qf 4729 2 IV IV NNP cord-022526-j9kg00qf 4729 3 prolapses prolapse NNS cord-022526-j9kg00qf 4729 4 occur occur VBP cord-022526-j9kg00qf 4729 5 most most RBS cord-022526-j9kg00qf 4729 6 commonly commonly RB cord-022526-j9kg00qf 4729 7 in in IN cord-022526-j9kg00qf 4729 8 horses horse NNS cord-022526-j9kg00qf 4729 9 with with IN cord-022526-j9kg00qf 4729 10 dystocia dystocia NN cord-022526-j9kg00qf 4729 11 . . . cord-022526-j9kg00qf 4730 1 73 73 CD cord-022526-j9kg00qf 4731 1 These these DT cord-022526-j9kg00qf 4731 2 prolapses prolapse NNS cord-022526-j9kg00qf 4731 3 are be VBP cord-022526-j9kg00qf 4731 4 almost almost RB cord-022526-j9kg00qf 4731 5 always always RB cord-022526-j9kg00qf 4731 6 fatal fatal JJ cord-022526-j9kg00qf 4731 7 because because IN cord-022526-j9kg00qf 4731 8 of of IN cord-022526-j9kg00qf 4731 9 stretching stretch VBG cord-022526-j9kg00qf 4731 10 and and CC cord-022526-j9kg00qf 4731 11 tearing tearing NN cord-022526-j9kg00qf 4731 12 of of IN cord-022526-j9kg00qf 4731 13 mesenteric mesenteric JJ cord-022526-j9kg00qf 4731 14 vasculature vasculature NN cord-022526-j9kg00qf 4731 15 , , , cord-022526-j9kg00qf 4731 16 with with IN cord-022526-j9kg00qf 4731 17 subsequent subsequent JJ cord-022526-j9kg00qf 4731 18 infarction infarction NN cord-022526-j9kg00qf 4731 19 of of IN cord-022526-j9kg00qf 4731 20 affected affected JJ cord-022526-j9kg00qf 4731 21 bowel bowel NN cord-022526-j9kg00qf 4731 22 . . . cord-022526-j9kg00qf 4732 1 Therefore therefore RB cord-022526-j9kg00qf 4732 2 euthanasia euthanasia NN cord-022526-j9kg00qf 4732 3 usually usually RB cord-022526-j9kg00qf 4732 4 is be VBZ cord-022526-j9kg00qf 4732 5 warranted warrant VBN cord-022526-j9kg00qf 4732 6 tend tend VBP cord-022526-j9kg00qf 4732 7 to to TO cord-022526-j9kg00qf 4732 8 occur occur VB cord-022526-j9kg00qf 4732 9 in in IN cord-022526-j9kg00qf 4732 10 young young JJ cord-022526-j9kg00qf 4732 11 horses horse NNS cord-022526-j9kg00qf 4732 12 ( ( -LRB- cord-022526-j9kg00qf 4732 13 63 63 CD cord-022526-j9kg00qf 4732 14 % % NN cord-022526-j9kg00qf 4732 15 were be VBD cord-022526-j9kg00qf 4732 16 less less JJR cord-022526-j9kg00qf 4732 17 than than IN cord-022526-j9kg00qf 4732 18 3 3 CD cord-022526-j9kg00qf 4732 19 years year NNS cord-022526-j9kg00qf 4732 20 old old JJ cord-022526-j9kg00qf 4732 21 in in IN cord-022526-j9kg00qf 4732 22 one one CD cord-022526-j9kg00qf 4732 23 study study NN cord-022526-j9kg00qf 4732 24 ) ) -RRB- cord-022526-j9kg00qf 4732 25 and and CC cord-022526-j9kg00qf 4732 26 may may MD cord-022526-j9kg00qf 4732 27 be be VB cord-022526-j9kg00qf 4732 28 associated associate VBN cord-022526-j9kg00qf 4732 29 with with IN cord-022526-j9kg00qf 4732 30 intestinal intestinal JJ cord-022526-j9kg00qf 4732 31 tapeworms tapeworm NNS cord-022526-j9kg00qf 4732 32 . . . cord-022526-j9kg00qf 4733 1 Horses horse NNS cord-022526-j9kg00qf 4733 2 show show VBP cord-022526-j9kg00qf 4733 3 highly highly RB cord-022526-j9kg00qf 4733 4 variable variable JJ cord-022526-j9kg00qf 4733 5 clinical clinical JJ cord-022526-j9kg00qf 4733 6 signs sign NNS cord-022526-j9kg00qf 4733 7 , , , cord-022526-j9kg00qf 4733 8 including include VBG cord-022526-j9kg00qf 4733 9 acute acute JJ cord-022526-j9kg00qf 4733 10 severe severe JJ cord-022526-j9kg00qf 4733 11 colic colic NN cord-022526-j9kg00qf 4733 12 , , , cord-022526-j9kg00qf 4733 13 intermittent intermittent JJ cord-022526-j9kg00qf 4733 14 pain pain NN cord-022526-j9kg00qf 4733 15 over over IN cord-022526-j9kg00qf 4733 16 a a DT cord-022526-j9kg00qf 4733 17 number number NN cord-022526-j9kg00qf 4733 18 of of IN cord-022526-j9kg00qf 4733 19 days day NNS cord-022526-j9kg00qf 4733 20 , , , cord-022526-j9kg00qf 4733 21 or or CC cord-022526-j9kg00qf 4733 22 chronic chronic JJ cord-022526-j9kg00qf 4733 23 weight weight NN cord-022526-j9kg00qf 4733 24 loss loss NN cord-022526-j9kg00qf 4733 25 . . . cord-022526-j9kg00qf 4734 1 64 64 CD cord-022526-j9kg00qf 4735 1 These these DT cord-022526-j9kg00qf 4735 2 variable variable JJ cord-022526-j9kg00qf 4735 3 presentations presentation NNS cord-022526-j9kg00qf 4735 4 likely likely RB cord-022526-j9kg00qf 4735 5 relate relate VBP cord-022526-j9kg00qf 4735 6 to to IN cord-022526-j9kg00qf 4735 7 the the DT cord-022526-j9kg00qf 4735 8 degree degree NN cord-022526-j9kg00qf 4735 9 to to TO cord-022526-j9kg00qf 4735 10 which which WDT cord-022526-j9kg00qf 4735 11 the the DT cord-022526-j9kg00qf 4735 12 cecum cecum NN cord-022526-j9kg00qf 4735 13 has have VBZ cord-022526-j9kg00qf 4735 14 intussuscepted intussuscept VBN cord-022526-j9kg00qf 4735 15 . . . cord-022526-j9kg00qf 4736 1 Initially initially RB cord-022526-j9kg00qf 4736 2 , , , cord-022526-j9kg00qf 4736 3 the the DT cord-022526-j9kg00qf 4736 4 cecal cecal JJ cord-022526-j9kg00qf 4736 5 tip tip NN cord-022526-j9kg00qf 4736 6 inverts invert NNS cord-022526-j9kg00qf 4736 7 , , , cord-022526-j9kg00qf 4736 8 creating create VBG cord-022526-j9kg00qf 4736 9 a a DT cord-022526-j9kg00qf 4736 10 cecocecal cecocecal JJ cord-022526-j9kg00qf 4736 11 intussusception intussusception NN cord-022526-j9kg00qf 4736 12 , , , cord-022526-j9kg00qf 4736 13 which which WDT cord-022526-j9kg00qf 4736 14 does do VBZ cord-022526-j9kg00qf 4736 15 not not RB cord-022526-j9kg00qf 4736 16 obstruct obstruct VB cord-022526-j9kg00qf 4736 17 flow flow NN cord-022526-j9kg00qf 4736 18 of of IN cord-022526-j9kg00qf 4736 19 ingesta ingesta NNP cord-022526-j9kg00qf 4736 20 . . . cord-022526-j9kg00qf 4737 1 As as IN cord-022526-j9kg00qf 4737 2 the the DT cord-022526-j9kg00qf 4737 3 intussusception intussusception NN cord-022526-j9kg00qf 4737 4 progresses progress VBZ cord-022526-j9kg00qf 4737 5 , , , cord-022526-j9kg00qf 4737 6 the the DT cord-022526-j9kg00qf 4737 7 cecum cecum NN cord-022526-j9kg00qf 4737 8 inverts invert VBZ cord-022526-j9kg00qf 4737 9 into into IN cord-022526-j9kg00qf 4737 10 the the DT cord-022526-j9kg00qf 4737 11 right right JJ cord-022526-j9kg00qf 4737 12 ventral ventral JJ cord-022526-j9kg00qf 4737 13 colon colon NN cord-022526-j9kg00qf 4737 14 ( ( -LRB- cord-022526-j9kg00qf 4737 15 cecocolic cecocolic JJ cord-022526-j9kg00qf 4737 16 intussusception intussusception NN cord-022526-j9kg00qf 4737 17 ) ) -RRB- cord-022526-j9kg00qf 4737 18 , , , cord-022526-j9kg00qf 4737 19 obstructs obstruct VBZ cord-022526-j9kg00qf 4737 20 flow flow NN cord-022526-j9kg00qf 4737 21 of of IN cord-022526-j9kg00qf 4737 22 ingesta ingesta NNP cord-022526-j9kg00qf 4737 23 , , , cord-022526-j9kg00qf 4737 24 and and CC cord-022526-j9kg00qf 4737 25 often often RB cord-022526-j9kg00qf 4737 26 causes cause VBZ cord-022526-j9kg00qf 4737 27 severe severe JJ cord-022526-j9kg00qf 4737 28 colic colic NN cord-022526-j9kg00qf 4737 29 . . . cord-022526-j9kg00qf 4738 1 The the DT cord-022526-j9kg00qf 4738 2 cause cause NN cord-022526-j9kg00qf 4738 3 of of IN cord-022526-j9kg00qf 4738 4 abdominal abdominal JJ cord-022526-j9kg00qf 4738 5 pain pain NN cord-022526-j9kg00qf 4738 6 is be VBZ cord-022526-j9kg00qf 4738 7 often often RB cord-022526-j9kg00qf 4738 8 difficult difficult JJ cord-022526-j9kg00qf 4738 9 to to TO cord-022526-j9kg00qf 4738 10 differentiate differentiate VB cord-022526-j9kg00qf 4738 11 in in IN cord-022526-j9kg00qf 4738 12 these these DT cord-022526-j9kg00qf 4738 13 cases case NNS cord-022526-j9kg00qf 4738 14 , , , cord-022526-j9kg00qf 4738 15 although although IN cord-022526-j9kg00qf 4738 16 detecting detect VBG cord-022526-j9kg00qf 4738 17 a a DT cord-022526-j9kg00qf 4738 18 mass mass NN cord-022526-j9kg00qf 4738 19 on on IN cord-022526-j9kg00qf 4738 20 the the DT cord-022526-j9kg00qf 4738 21 right right JJ cord-022526-j9kg00qf 4738 22 side side NN cord-022526-j9kg00qf 4738 23 of of IN cord-022526-j9kg00qf 4738 24 the the DT cord-022526-j9kg00qf 4738 25 abdomen abdomen NN cord-022526-j9kg00qf 4738 26 by by IN cord-022526-j9kg00qf 4738 27 per per IN cord-022526-j9kg00qf 4738 28 rectal rectal JJ cord-022526-j9kg00qf 4738 29 palpation palpation NN cord-022526-j9kg00qf 4738 30 or or CC cord-022526-j9kg00qf 4738 31 ultrasound ultrasound NN cord-022526-j9kg00qf 4738 32 examination examination NN cord-022526-j9kg00qf 4738 33 sometimes sometimes RB cord-022526-j9kg00qf 4738 34 is be VBZ cord-022526-j9kg00qf 4738 35 possible possible JJ cord-022526-j9kg00qf 4738 36 . . . cord-022526-j9kg00qf 4739 1 63 63 CD cord-022526-j9kg00qf 4739 2 , , , cord-022526-j9kg00qf 4739 3 64 64 CD cord-022526-j9kg00qf 4739 4 Treatment treatment NN cord-022526-j9kg00qf 4739 5 involves involve VBZ cord-022526-j9kg00qf 4739 6 manual manual JJ cord-022526-j9kg00qf 4739 7 surgical surgical JJ cord-022526-j9kg00qf 4739 8 reduction reduction NN cord-022526-j9kg00qf 4739 9 by by IN cord-022526-j9kg00qf 4739 10 retracting retract VBG cord-022526-j9kg00qf 4739 11 the the DT cord-022526-j9kg00qf 4739 12 intussusceptum intussusceptum NN cord-022526-j9kg00qf 4739 13 directly directly RB cord-022526-j9kg00qf 4739 14 63 63 CD cord-022526-j9kg00qf 4739 15 or or CC cord-022526-j9kg00qf 4739 16 via via IN cord-022526-j9kg00qf 4739 17 an an DT cord-022526-j9kg00qf 4739 18 enterotomy enterotomy NN cord-022526-j9kg00qf 4739 19 in in IN cord-022526-j9kg00qf 4739 20 the the DT cord-022526-j9kg00qf 4739 21 right right JJ cord-022526-j9kg00qf 4739 22 ventral ventral JJ cord-022526-j9kg00qf 4739 23 colon colon NN cord-022526-j9kg00qf 4739 24 . . . cord-022526-j9kg00qf 4740 1 65 65 CD cord-022526-j9kg00qf 4741 1 However however RB cord-022526-j9kg00qf 4741 2 , , , cord-022526-j9kg00qf 4741 3 a a DT cord-022526-j9kg00qf 4741 4 number number NN cord-022526-j9kg00qf 4741 5 of of IN cord-022526-j9kg00qf 4741 6 cases case NNS cord-022526-j9kg00qf 4741 7 occur occur VBP cord-022526-j9kg00qf 4741 8 in in IN cord-022526-j9kg00qf 4741 9 which which WDT cord-022526-j9kg00qf 4741 10 one one PRP cord-022526-j9kg00qf 4741 11 can can MD cord-022526-j9kg00qf 4741 12 not not RB cord-022526-j9kg00qf 4741 13 reduce reduce VB cord-022526-j9kg00qf 4741 14 the the DT cord-022526-j9kg00qf 4741 15 cecum cecum NN cord-022526-j9kg00qf 4741 16 readily readily RB cord-022526-j9kg00qf 4741 17 because because IN cord-022526-j9kg00qf 4741 18 of of IN cord-022526-j9kg00qf 4741 19 severe severe JJ cord-022526-j9kg00qf 4741 20 thickening thickening NN cord-022526-j9kg00qf 4741 21 or or CC cord-022526-j9kg00qf 4741 22 in in IN cord-022526-j9kg00qf 4741 23 which which WDT cord-022526-j9kg00qf 4741 24 surgical surgical JJ cord-022526-j9kg00qf 4741 25 procedures procedure NNS cord-022526-j9kg00qf 4741 26 result result VBP cord-022526-j9kg00qf 4741 27 in in IN cord-022526-j9kg00qf 4741 28 fatal fatal JJ cord-022526-j9kg00qf 4741 29 contamination contamination NN cord-022526-j9kg00qf 4741 30 . . . cord-022526-j9kg00qf 4742 1 For for IN cord-022526-j9kg00qf 4742 2 example example NN cord-022526-j9kg00qf 4742 3 , , , cord-022526-j9kg00qf 4742 4 one one CD cord-022526-j9kg00qf 4742 5 report report NN cord-022526-j9kg00qf 4742 6 stated state VBD cord-022526-j9kg00qf 4742 7 that that IN cord-022526-j9kg00qf 4742 8 8 8 CD cord-022526-j9kg00qf 4742 9 of of IN cord-022526-j9kg00qf 4742 10 11 11 CD cord-022526-j9kg00qf 4742 11 horses horse NNS cord-022526-j9kg00qf 4742 12 were be VBD cord-022526-j9kg00qf 4742 13 euthanized euthanize VBN cord-022526-j9kg00qf 4742 14 in in IN cord-022526-j9kg00qf 4742 15 the the DT cord-022526-j9kg00qf 4742 16 perioperative perioperative JJ cord-022526-j9kg00qf 4742 17 period period NN cord-022526-j9kg00qf 4742 18 because because IN cord-022526-j9kg00qf 4742 19 of of IN cord-022526-j9kg00qf 4742 20 complications complication NNS cord-022526-j9kg00qf 4742 21 , , , cord-022526-j9kg00qf 4742 22 63 63 CD cord-022526-j9kg00qf 4742 23 and and CC cord-022526-j9kg00qf 4742 24 another another DT cord-022526-j9kg00qf 4742 25 report report NN cord-022526-j9kg00qf 4742 26 stated state VBD cord-022526-j9kg00qf 4742 27 that that IN cord-022526-j9kg00qf 4742 28 12 12 CD cord-022526-j9kg00qf 4742 29 of of IN cord-022526-j9kg00qf 4742 30 30 30 CD cord-022526-j9kg00qf 4742 31 horses horse NNS cord-022526-j9kg00qf 4742 32 were be VBD cord-022526-j9kg00qf 4742 33 euthanized euthanize VBN cord-022526-j9kg00qf 4742 34 before before IN cord-022526-j9kg00qf 4742 35 or or CC cord-022526-j9kg00qf 4742 36 during during IN cord-022526-j9kg00qf 4742 37 surgery surgery NN cord-022526-j9kg00qf 4742 38 . . . cord-022526-j9kg00qf 4743 1 The the DT cord-022526-j9kg00qf 4743 2 latter latter JJ cord-022526-j9kg00qf 4743 3 included include VBD cord-022526-j9kg00qf 4743 4 all all DT cord-022526-j9kg00qf 4743 5 of of IN cord-022526-j9kg00qf 4743 6 the the DT cord-022526-j9kg00qf 4743 7 horses horse NNS cord-022526-j9kg00qf 4743 8 with with IN cord-022526-j9kg00qf 4743 9 chronic chronic JJ cord-022526-j9kg00qf 4743 10 disease disease NN cord-022526-j9kg00qf 4743 11 because because IN cord-022526-j9kg00qf 4743 12 of of IN cord-022526-j9kg00qf 4743 13 irreversible irreversible JJ cord-022526-j9kg00qf 4743 14 changes change NNS cord-022526-j9kg00qf 4743 15 to to IN cord-022526-j9kg00qf 4743 16 the the DT cord-022526-j9kg00qf 4743 17 cecum cecum NN cord-022526-j9kg00qf 4743 18 . . . cord-022526-j9kg00qf 4744 1 64 64 CD cord-022526-j9kg00qf 4745 1 However however RB cord-022526-j9kg00qf 4745 2 , , , cord-022526-j9kg00qf 4745 3 one one CD cord-022526-j9kg00qf 4745 4 recent recent JJ cord-022526-j9kg00qf 4745 5 report report NN cord-022526-j9kg00qf 4745 6 on on IN cord-022526-j9kg00qf 4745 7 cecocolic cecocolic NNP cord-022526-j9kg00qf 4745 8 intussusceptions intussusception NNS cord-022526-j9kg00qf 4745 9 indicated indicate VBD cord-022526-j9kg00qf 4745 10 that that IN cord-022526-j9kg00qf 4745 11 seven seven CD cord-022526-j9kg00qf 4745 12 of of IN cord-022526-j9kg00qf 4745 13 eight eight CD cord-022526-j9kg00qf 4745 14 horses horse NNS cord-022526-j9kg00qf 4745 15 that that WDT cord-022526-j9kg00qf 4745 16 underwent undergo VBD cord-022526-j9kg00qf 4745 17 right right JJ cord-022526-j9kg00qf 4745 18 ventral ventral JJ cord-022526-j9kg00qf 4745 19 colon colon NN cord-022526-j9kg00qf 4745 20 enterotomy enterotomy NNP cord-022526-j9kg00qf 4745 21 and and CC cord-022526-j9kg00qf 4745 22 cecal cecal JJ cord-022526-j9kg00qf 4745 23 resection resection NN cord-022526-j9kg00qf 4745 24 survived survive VBD cord-022526-j9kg00qf 4745 25 long long JJ cord-022526-j9kg00qf 4745 26 - - HYPH cord-022526-j9kg00qf 4745 27 term term NN cord-022526-j9kg00qf 4745 28 , , , cord-022526-j9kg00qf 4745 29 65 65 CD cord-022526-j9kg00qf 4745 30 suggesting suggest VBG cord-022526-j9kg00qf 4745 31 that that IN cord-022526-j9kg00qf 4745 32 continued continue VBN cord-022526-j9kg00qf 4745 33 improvements improvement NNS cord-022526-j9kg00qf 4745 34 in in IN cord-022526-j9kg00qf 4745 35 surgical surgical JJ cord-022526-j9kg00qf 4745 36 techniques technique NNS cord-022526-j9kg00qf 4745 37 may may MD cord-022526-j9kg00qf 4745 38 improve improve VB cord-022526-j9kg00qf 4745 39 the the DT cord-022526-j9kg00qf 4745 40 prognosis prognosis NN cord-022526-j9kg00qf 4745 41 . . . cord-022526-j9kg00qf 4746 1 Colocolic Colocolic NNP cord-022526-j9kg00qf 4746 2 intussusceptions intussusception NNS cord-022526-j9kg00qf 4746 3 are be VBP cord-022526-j9kg00qf 4746 4 rare rare JJ cord-022526-j9kg00qf 4746 5 but but CC cord-022526-j9kg00qf 4746 6 have have VBP cord-022526-j9kg00qf 4746 7 been be VBN cord-022526-j9kg00qf 4746 8 reported report VBN cord-022526-j9kg00qf 4746 9 to to TO cord-022526-j9kg00qf 4746 10 affect affect VB cord-022526-j9kg00qf 4746 11 the the DT cord-022526-j9kg00qf 4746 12 pelvic pelvic JJ cord-022526-j9kg00qf 4746 13 flexure flexure NN cord-022526-j9kg00qf 4746 14 and and CC cord-022526-j9kg00qf 4746 15 the the DT cord-022526-j9kg00qf 4746 16 left left JJ cord-022526-j9kg00qf 4746 17 colons colon NNS cord-022526-j9kg00qf 4746 18 . . . cord-022526-j9kg00qf 4747 1 [ [ -LRB- cord-022526-j9kg00qf 4747 2 66 66 CD cord-022526-j9kg00qf 4747 3 ] ] -RRB- cord-022526-j9kg00qf 4747 4 [ [ -LRB- cord-022526-j9kg00qf 4747 5 67 67 CD cord-022526-j9kg00qf 4747 6 ] ] -RRB- cord-022526-j9kg00qf 4748 1 [ [ -LRB- cord-022526-j9kg00qf 4748 2 68 68 CD cord-022526-j9kg00qf 4748 3 ] ] -RRB- cord-022526-j9kg00qf 4749 1 [ [ -LRB- cord-022526-j9kg00qf 4749 2 69 69 CD cord-022526-j9kg00qf 4749 3 ] ] -RRB- cord-022526-j9kg00qf 4750 1 Although although IN cord-022526-j9kg00qf 4750 2 the the DT cord-022526-j9kg00qf 4750 3 condition condition NN cord-022526-j9kg00qf 4750 4 is be VBZ cord-022526-j9kg00qf 4750 5 reported report VBN cord-022526-j9kg00qf 4750 6 to to TO cord-022526-j9kg00qf 4750 7 be be VB cord-022526-j9kg00qf 4750 8 more more RBR cord-022526-j9kg00qf 4750 9 common common JJ cord-022526-j9kg00qf 4750 10 in in IN cord-022526-j9kg00qf 4750 11 young young JJ cord-022526-j9kg00qf 4750 12 horses horse NNS cord-022526-j9kg00qf 4750 13 , , , cord-022526-j9kg00qf 4750 14 67 67 CD cord-022526-j9kg00qf 4750 15 - - SYM cord-022526-j9kg00qf 4750 16 69 69 CD cord-022526-j9kg00qf 4750 17 the the DT cord-022526-j9kg00qf 4750 18 condition condition NN cord-022526-j9kg00qf 4750 19 may may MD cord-022526-j9kg00qf 4750 20 affect affect VB cord-022526-j9kg00qf 4750 21 older old JJR cord-022526-j9kg00qf 4750 22 horses horse NNS cord-022526-j9kg00qf 4750 23 . . . cord-022526-j9kg00qf 4751 1 66 66 CD cord-022526-j9kg00qf 4751 2 Clinical clinical JJ cord-022526-j9kg00qf 4751 3 findings finding NNS cord-022526-j9kg00qf 4751 4 may may MD cord-022526-j9kg00qf 4751 5 include include VB cord-022526-j9kg00qf 4751 6 a a DT cord-022526-j9kg00qf 4751 7 palpable palpable JJ cord-022526-j9kg00qf 4751 8 mass mass NN cord-022526-j9kg00qf 4751 9 on on IN cord-022526-j9kg00qf 4751 10 the the DT cord-022526-j9kg00qf 4751 11 left left JJ cord-022526-j9kg00qf 4751 12 side side NN cord-022526-j9kg00qf 4751 13 of of IN cord-022526-j9kg00qf 4751 14 the the DT cord-022526-j9kg00qf 4751 15 abdomen abdomen NN cord-022526-j9kg00qf 4751 16 . . . cord-022526-j9kg00qf 4752 1 67 67 CD cord-022526-j9kg00qf 4752 2 Ultrasonography Ultrasonography NNP cord-022526-j9kg00qf 4752 3 also also RB cord-022526-j9kg00qf 4752 4 may may MD cord-022526-j9kg00qf 4752 5 be be VB cord-022526-j9kg00qf 4752 6 useful useful JJ cord-022526-j9kg00qf 4752 7 . . . cord-022526-j9kg00qf 4753 1 Treatment treatment NN cord-022526-j9kg00qf 4753 2 requires require VBZ cord-022526-j9kg00qf 4753 3 manual manual JJ cord-022526-j9kg00qf 4753 4 reduction reduction NN cord-022526-j9kg00qf 4753 5 of of IN cord-022526-j9kg00qf 4753 6 the the DT cord-022526-j9kg00qf 4753 7 intussusception intussusception NN cord-022526-j9kg00qf 4753 8 at at IN cord-022526-j9kg00qf 4753 9 surgery surgery NN cord-022526-j9kg00qf 4753 10 , , , cord-022526-j9kg00qf 4753 11 67 67 CD cord-022526-j9kg00qf 4753 12 , , , cord-022526-j9kg00qf 4753 13 69 69 CD cord-022526-j9kg00qf 4753 14 or or CC cord-022526-j9kg00qf 4753 15 resection resection NN cord-022526-j9kg00qf 4753 16 of of IN cord-022526-j9kg00qf 4753 17 affected affected JJ cord-022526-j9kg00qf 4753 18 bowel bowel NN cord-022526-j9kg00qf 4753 19 . . . cord-022526-j9kg00qf 4754 1 66 66 CD cord-022526-j9kg00qf 4755 1 Because because IN cord-022526-j9kg00qf 4755 2 the the DT cord-022526-j9kg00qf 4755 3 left left JJ cord-022526-j9kg00qf 4755 4 colons colon NNS cord-022526-j9kg00qf 4755 5 may may MD cord-022526-j9kg00qf 4755 6 be be VB cord-022526-j9kg00qf 4755 7 exteriorized exteriorize VBN cord-022526-j9kg00qf 4755 8 extensively extensively RB cord-022526-j9kg00qf 4755 9 and and CC cord-022526-j9kg00qf 4755 10 manipulated manipulate VBN cord-022526-j9kg00qf 4755 11 at at IN cord-022526-j9kg00qf 4755 12 surgery surgery NN cord-022526-j9kg00qf 4755 13 , , , cord-022526-j9kg00qf 4755 14 66 66 CD cord-022526-j9kg00qf 4755 15 - - SYM cord-022526-j9kg00qf 4755 16 69 69 CD cord-022526-j9kg00qf 4755 17 the the DT cord-022526-j9kg00qf 4755 18 prognosis prognosis NN cord-022526-j9kg00qf 4755 19 is be VBZ cord-022526-j9kg00qf 4755 20 fair fair JJ cord-022526-j9kg00qf 4755 21 . . . cord-022526-j9kg00qf 4756 1 Rectal rectal JJ cord-022526-j9kg00qf 4756 2 prolapse prolapse NN cord-022526-j9kg00qf 4756 3 may may MD cord-022526-j9kg00qf 4756 4 occur occur VB cord-022526-j9kg00qf 4756 5 following follow VBG cord-022526-j9kg00qf 4756 6 any any DT cord-022526-j9kg00qf 4756 7 disease disease NN cord-022526-j9kg00qf 4756 8 that that WDT cord-022526-j9kg00qf 4756 9 causes cause VBZ cord-022526-j9kg00qf 4756 10 tenesmus tenesmus NNP cord-022526-j9kg00qf 4756 11 , , , cord-022526-j9kg00qf 4756 12 including include VBG cord-022526-j9kg00qf 4756 13 diarrhea diarrhea NN cord-022526-j9kg00qf 4756 14 , , , cord-022526-j9kg00qf 4756 15 rectal rectal JJ cord-022526-j9kg00qf 4756 16 neoplasia neoplasia NN cord-022526-j9kg00qf 4756 17 , , , cord-022526-j9kg00qf 4756 18 and and CC cord-022526-j9kg00qf 4756 19 parasitism parasitism NN cord-022526-j9kg00qf 4756 20 , , , cord-022526-j9kg00qf 4756 21 70 70 CD cord-022526-j9kg00qf 4756 22 or or CC cord-022526-j9kg00qf 4756 23 prolapse prolapse NN cord-022526-j9kg00qf 4756 24 can can MD cord-022526-j9kg00qf 4756 25 occur occur VB cord-022526-j9kg00qf 4756 26 following follow VBG cord-022526-j9kg00qf 4756 27 elevations elevation NNS cord-022526-j9kg00qf 4756 28 in in IN cord-022526-j9kg00qf 4756 29 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 4756 30 pressure pressure NN cord-022526-j9kg00qf 4756 31 during during IN cord-022526-j9kg00qf 4756 32 parturition parturition NN cord-022526-j9kg00qf 4756 33 or or CC cord-022526-j9kg00qf 4756 34 episodes episode NNS cord-022526-j9kg00qf 4756 35 of of IN cord-022526-j9kg00qf 4756 36 coughing coughing NN cord-022526-j9kg00qf 4756 37 . . . cord-022526-j9kg00qf 4757 1 71 71 CD cord-022526-j9kg00qf 4757 2 , , , cord-022526-j9kg00qf 4757 3 72 72 CD cord-022526-j9kg00qf 4757 4 Rectal rectal JJ cord-022526-j9kg00qf 4757 5 prolapses prolapse NNS cord-022526-j9kg00qf 4757 6 are be VBP cord-022526-j9kg00qf 4757 7 classified classify VBN cord-022526-j9kg00qf 4757 8 into into IN cord-022526-j9kg00qf 4757 9 four four CD cord-022526-j9kg00qf 4757 10 categories category NNS cord-022526-j9kg00qf 4757 11 ( ( -LRB- cord-022526-j9kg00qf 4757 12 Table Table NNP cord-022526-j9kg00qf 4757 13 13 13 CD cord-022526-j9kg00qf 4757 14 . . . cord-022526-j9kg00qf 4758 1 14 14 CD cord-022526-j9kg00qf 4758 2 - - SYM cord-022526-j9kg00qf 4758 3 1 1 CD cord-022526-j9kg00qf 4758 4 ) ) -RRB- cord-022526-j9kg00qf 4759 1 based base VBN cord-022526-j9kg00qf 4759 2 on on IN cord-022526-j9kg00qf 4759 3 the the DT cord-022526-j9kg00qf 4759 4 extent extent NN cord-022526-j9kg00qf 4759 5 of of IN cord-022526-j9kg00qf 4759 6 tissue tissue NN cord-022526-j9kg00qf 4759 7 prolapsed prolapsed JJ cord-022526-j9kg00qf 4759 8 and and CC cord-022526-j9kg00qf 4759 9 the the DT cord-022526-j9kg00qf 4759 10 severity severity NN cord-022526-j9kg00qf 4759 11 . . . cord-022526-j9kg00qf 4760 1 Type type NN cord-022526-j9kg00qf 4760 2 I -PRON- PRP cord-022526-j9kg00qf 4760 3 rectal rectal JJ cord-022526-j9kg00qf 4760 4 prolapse prolapse NN cord-022526-j9kg00qf 4760 5 is be VBZ cord-022526-j9kg00qf 4760 6 most most RBS cord-022526-j9kg00qf 4760 7 common common JJ cord-022526-j9kg00qf 4760 8 and and CC cord-022526-j9kg00qf 4760 9 is be VBZ cord-022526-j9kg00qf 4760 10 characterized characterize VBN cord-022526-j9kg00qf 4760 11 by by IN cord-022526-j9kg00qf 4760 12 a a DT cord-022526-j9kg00qf 4760 13 Intussusception Intussusception NNP cord-022526-j9kg00qf 4760 14 of of IN cord-022526-j9kg00qf 4760 15 rectum rectum NN cord-022526-j9kg00qf 4760 16 and and CC cord-022526-j9kg00qf 4760 17 Poor poor JJ cord-022526-j9kg00qf 4760 18 small small JJ cord-022526-j9kg00qf 4760 19 colon colon NN cord-022526-j9kg00qf 4760 20 through through IN cord-022526-j9kg00qf 4760 21 the the DT cord-022526-j9kg00qf 4760 22 anus anus NN cord-022526-j9kg00qf 4760 23 based base VBN cord-022526-j9kg00qf 4760 24 on on IN cord-022526-j9kg00qf 4760 25 physical physical JJ cord-022526-j9kg00qf 4760 26 examination examination NN cord-022526-j9kg00qf 4760 27 findings finding NNS cord-022526-j9kg00qf 4760 28 . . . cord-022526-j9kg00qf 4761 1 However however RB cord-022526-j9kg00qf 4761 2 , , , cord-022526-j9kg00qf 4761 3 confirmation confirmation NN cord-022526-j9kg00qf 4761 4 of of IN cord-022526-j9kg00qf 4761 5 severe severe JJ cord-022526-j9kg00qf 4761 6 small small JJ cord-022526-j9kg00qf 4761 7 colonic colonic JJ cord-022526-j9kg00qf 4761 8 injury injury NN cord-022526-j9kg00qf 4761 9 requires require VBZ cord-022526-j9kg00qf 4761 10 abdominal abdominal JJ cord-022526-j9kg00qf 4761 11 exploration exploration NN cord-022526-j9kg00qf 4761 12 via via IN cord-022526-j9kg00qf 4761 13 a a DT cord-022526-j9kg00qf 4761 14 midline midline JJ cord-022526-j9kg00qf 4761 15 approach approach NN cord-022526-j9kg00qf 4761 16 or or CC cord-022526-j9kg00qf 4761 17 laparoscopy laparoscopy NN cord-022526-j9kg00qf 4761 18 . . . cord-022526-j9kg00qf 4762 1 76 76 CD cord-022526-j9kg00qf 4763 1 A a DT cord-022526-j9kg00qf 4763 2 horse horse NN cord-022526-j9kg00qf 4763 3 with with IN cord-022526-j9kg00qf 4763 4 compromised compromise VBN cord-022526-j9kg00qf 4763 5 small small JJ cord-022526-j9kg00qf 4763 6 colon colon NN cord-022526-j9kg00qf 4763 7 conceivably conceivably RB cord-022526-j9kg00qf 4763 8 could could MD cord-022526-j9kg00qf 4763 9 undergo undergo VB cord-022526-j9kg00qf 4763 10 a a DT cord-022526-j9kg00qf 4763 11 colostomy colostomy NN cord-022526-j9kg00qf 4763 12 of of IN cord-022526-j9kg00qf 4763 13 the the DT cord-022526-j9kg00qf 4763 14 proximal proximal JJ cord-022526-j9kg00qf 4763 15 small small JJ cord-022526-j9kg00qf 4763 16 colon colon NN cord-022526-j9kg00qf 4763 17 , , , cord-022526-j9kg00qf 4763 18 but but CC cord-022526-j9kg00qf 4763 19 the the DT cord-022526-j9kg00qf 4763 20 compromised compromised JJ cord-022526-j9kg00qf 4763 21 small small JJ cord-022526-j9kg00qf 4763 22 colon colon NN cord-022526-j9kg00qf 4763 23 typically typically RB cord-022526-j9kg00qf 4763 24 necroses necrose VBZ cord-022526-j9kg00qf 4763 25 beyond beyond IN cord-022526-j9kg00qf 4763 26 that that DT cord-022526-j9kg00qf 4763 27 which which WDT cord-022526-j9kg00qf 4763 28 can can MD cord-022526-j9kg00qf 4763 29 be be VB cord-022526-j9kg00qf 4763 30 resected resect VBN cord-022526-j9kg00qf 4763 31 via via IN cord-022526-j9kg00qf 4763 32 a a DT cord-022526-j9kg00qf 4763 33 midline midline JJ cord-022526-j9kg00qf 4763 34 abdominal abdominal JJ cord-022526-j9kg00qf 4763 35 approach approach NN cord-022526-j9kg00qf 4763 36 . . . cord-022526-j9kg00qf 4764 1 74 74 CD cord-022526-j9kg00qf 4765 1 Nonstrangulating Nonstrangulating NNP cord-022526-j9kg00qf 4765 2 infarction infarction NN cord-022526-j9kg00qf 4765 3 occurs occur VBZ cord-022526-j9kg00qf 4765 4 following follow VBG cord-022526-j9kg00qf 4765 5 cranial cranial JJ cord-022526-j9kg00qf 4765 6 mesenteric mesenteric JJ cord-022526-j9kg00qf 4765 7 arteritis arteritis NN cord-022526-j9kg00qf 4765 8 caused cause VBN cord-022526-j9kg00qf 4765 9 by by IN cord-022526-j9kg00qf 4765 10 migration migration NN cord-022526-j9kg00qf 4765 11 of of IN cord-022526-j9kg00qf 4765 12 Strongylus Strongylus NNP cord-022526-j9kg00qf 4765 13 vulgaris vulgaris NN cord-022526-j9kg00qf 4765 14 and and CC cord-022526-j9kg00qf 4765 15 has have VBZ cord-022526-j9kg00qf 4765 16 become become VBN cord-022526-j9kg00qf 4765 17 a a DT cord-022526-j9kg00qf 4765 18 rare rare JJ cord-022526-j9kg00qf 4765 19 disorder disorder NN cord-022526-j9kg00qf 4765 20 since since IN cord-022526-j9kg00qf 4765 21 the the DT cord-022526-j9kg00qf 4765 22 advent advent NN cord-022526-j9kg00qf 4765 23 of of IN cord-022526-j9kg00qf 4765 24 broad broad JJ cord-022526-j9kg00qf 4765 25 - - HYPH cord-022526-j9kg00qf 4765 26 spectrum spectrum NN cord-022526-j9kg00qf 4765 27 anthelmintics anthelmintic NNS cord-022526-j9kg00qf 4765 28 . . . cord-022526-j9kg00qf 4766 1 Although although IN cord-022526-j9kg00qf 4766 2 thromboemboli thromboemboli NNS cord-022526-j9kg00qf 4766 3 have have VBP cord-022526-j9kg00qf 4766 4 been be VBN cord-022526-j9kg00qf 4766 5 implicated implicate VBN cord-022526-j9kg00qf 4766 6 in in IN cord-022526-j9kg00qf 4766 7 the the DT cord-022526-j9kg00qf 4766 8 pathogenesis pathogenesis NN cord-022526-j9kg00qf 4766 9 of of IN cord-022526-j9kg00qf 4766 10 this this DT cord-022526-j9kg00qf 4766 11 disease disease NN cord-022526-j9kg00qf 4766 12 , , , cord-022526-j9kg00qf 4766 13 careful careful JJ cord-022526-j9kg00qf 4766 14 dissection dissection NN cord-022526-j9kg00qf 4766 15 of of IN cord-022526-j9kg00qf 4766 16 naturally naturally RB cord-022526-j9kg00qf 4766 17 occurring occur VBG cord-022526-j9kg00qf 4766 18 lesions lesion NNS cord-022526-j9kg00qf 4766 19 has have VBZ cord-022526-j9kg00qf 4766 20 not not RB cord-022526-j9kg00qf 4766 21 revealed reveal VBN cord-022526-j9kg00qf 4766 22 the the DT cord-022526-j9kg00qf 4766 23 presence presence NN cord-022526-j9kg00qf 4766 24 of of IN cord-022526-j9kg00qf 4766 25 thrombi thrombi NNP cord-022526-j9kg00qf 4766 26 at at IN cord-022526-j9kg00qf 4766 27 the the DT cord-022526-j9kg00qf 4766 28 site site NN cord-022526-j9kg00qf 4766 29 of of IN cord-022526-j9kg00qf 4766 30 intestinal intestinal JJ cord-022526-j9kg00qf 4766 31 infarctions infarction NNS cord-022526-j9kg00qf 4766 32 in in IN cord-022526-j9kg00qf 4766 33 most most JJS cord-022526-j9kg00qf 4766 34 cases case NNS cord-022526-j9kg00qf 4766 35 . . . cord-022526-j9kg00qf 4767 1 77 77 CD cord-022526-j9kg00qf 4768 1 These these DT cord-022526-j9kg00qf 4768 2 findings finding NNS cord-022526-j9kg00qf 4768 3 suggest suggest VBP cord-022526-j9kg00qf 4768 4 that that IN cord-022526-j9kg00qf 4768 5 vasospasm vasospasm NN cord-022526-j9kg00qf 4768 6 plays play VBZ cord-022526-j9kg00qf 4768 7 an an DT cord-022526-j9kg00qf 4768 8 important important JJ cord-022526-j9kg00qf 4768 9 role role NN cord-022526-j9kg00qf 4768 10 in in IN cord-022526-j9kg00qf 4768 11 this this DT cord-022526-j9kg00qf 4768 12 disease disease NN cord-022526-j9kg00qf 4768 13 . . . cord-022526-j9kg00qf 4769 1 78 78 CD cord-022526-j9kg00qf 4769 2 Clinical clinical JJ cord-022526-j9kg00qf 4769 3 signs sign NNS cord-022526-j9kg00qf 4769 4 vary vary VBP cord-022526-j9kg00qf 4769 5 greatly greatly RB cord-022526-j9kg00qf 4769 6 depending depend VBG cord-022526-j9kg00qf 4769 7 on on IN cord-022526-j9kg00qf 4769 8 the the DT cord-022526-j9kg00qf 4769 9 extent extent NN cord-022526-j9kg00qf 4769 10 to to TO cord-022526-j9kg00qf 4769 11 which which WDT cord-022526-j9kg00qf 4769 12 arterial arterial JJ cord-022526-j9kg00qf 4769 13 flow flow NN cord-022526-j9kg00qf 4769 14 is be VBZ cord-022526-j9kg00qf 4769 15 reduced reduce VBN cord-022526-j9kg00qf 4769 16 and and CC cord-022526-j9kg00qf 4769 17 the the DT cord-022526-j9kg00qf 4769 18 segment segment NN cord-022526-j9kg00qf 4769 19 of of IN cord-022526-j9kg00qf 4769 20 intestine intestine NN cord-022526-j9kg00qf 4769 21 affected affect VBN cord-022526-j9kg00qf 4769 22 . . . cord-022526-j9kg00qf 4770 1 Any any DT cord-022526-j9kg00qf 4770 2 segment segment NN cord-022526-j9kg00qf 4770 3 of of IN cord-022526-j9kg00qf 4770 4 intestine intestine NN cord-022526-j9kg00qf 4770 5 supplied supply VBN cord-022526-j9kg00qf 4770 6 by by IN cord-022526-j9kg00qf 4770 7 the the DT cord-022526-j9kg00qf 4770 8 cranial cranial JJ cord-022526-j9kg00qf 4770 9 mesenteric mesenteric JJ cord-022526-j9kg00qf 4770 10 artery artery NN cord-022526-j9kg00qf 4770 11 or or CC cord-022526-j9kg00qf 4770 12 one one CD cord-022526-j9kg00qf 4770 13 of of IN cord-022526-j9kg00qf 4770 14 its -PRON- PRP$ cord-022526-j9kg00qf 4770 15 major major JJ cord-022526-j9kg00qf 4770 16 branches branch NNS cord-022526-j9kg00qf 4770 17 may may MD cord-022526-j9kg00qf 4770 18 be be VB cord-022526-j9kg00qf 4770 19 affected affect VBN cord-022526-j9kg00qf 4770 20 , , , cord-022526-j9kg00qf 4770 21 but but CC cord-022526-j9kg00qf 4770 22 the the DT cord-022526-j9kg00qf 4770 23 distal distal JJ cord-022526-j9kg00qf 4770 24 small small JJ cord-022526-j9kg00qf 4770 25 intestine intestine NN cord-022526-j9kg00qf 4770 26 and and CC cord-022526-j9kg00qf 4770 27 large large JJ cord-022526-j9kg00qf 4770 28 colon colon NN cord-022526-j9kg00qf 4770 29 are be VBP cord-022526-j9kg00qf 4770 30 more more RBR cord-022526-j9kg00qf 4770 31 commonly commonly RB cord-022526-j9kg00qf 4770 32 involved involve VBN cord-022526-j9kg00qf 4770 33 . . . cord-022526-j9kg00qf 4771 1 No no DT cord-022526-j9kg00qf 4771 2 clinical clinical JJ cord-022526-j9kg00qf 4771 3 variables variable NNS cord-022526-j9kg00qf 4771 4 exist exist VBP cord-022526-j9kg00qf 4771 5 that that IN cord-022526-j9kg00qf 4771 6 one one PRP cord-022526-j9kg00qf 4771 7 can can MD cord-022526-j9kg00qf 4771 8 use use VB cord-022526-j9kg00qf 4771 9 to to TO cord-022526-j9kg00qf 4771 10 differentiate differentiate VB cord-022526-j9kg00qf 4771 11 this this DT cord-022526-j9kg00qf 4771 12 disease disease NN cord-022526-j9kg00qf 4771 13 from from IN cord-022526-j9kg00qf 4771 14 strangulating strangulate VBG cord-022526-j9kg00qf 4771 15 obstruction obstruction NN cord-022526-j9kg00qf 4771 16 reliably reliably RB cord-022526-j9kg00qf 4771 17 . . . cord-022526-j9kg00qf 4772 1 In in IN cord-022526-j9kg00qf 4772 2 some some DT cord-022526-j9kg00qf 4772 3 cases case NNS cord-022526-j9kg00qf 4772 4 , , , cord-022526-j9kg00qf 4772 5 massive massive JJ cord-022526-j9kg00qf 4772 6 infarction infarction NN cord-022526-j9kg00qf 4772 7 results result NNS cord-022526-j9kg00qf 4772 8 in in IN cord-022526-j9kg00qf 4772 9 acute acute JJ cord-022526-j9kg00qf 4772 10 , , , cord-022526-j9kg00qf 4772 11 severe severe JJ cord-022526-j9kg00qf 4772 12 colic colic NN cord-022526-j9kg00qf 4772 13 . . . cord-022526-j9kg00qf 4773 1 77 77 CD cord-022526-j9kg00qf 4774 1 Occasionally occasionally RB cord-022526-j9kg00qf 4774 2 , , , cord-022526-j9kg00qf 4774 3 one one PRP cord-022526-j9kg00qf 4774 4 may may MD cord-022526-j9kg00qf 4774 5 detect detect VB cord-022526-j9kg00qf 4774 6 an an DT cord-022526-j9kg00qf 4774 7 abnormal abnormal JJ cord-022526-j9kg00qf 4774 8 mass mass NN cord-022526-j9kg00qf 4774 9 and and CC cord-022526-j9kg00qf 4774 10 fremitus fremitus NN cord-022526-j9kg00qf 4774 11 on on IN cord-022526-j9kg00qf 4774 12 palpation palpation NN cord-022526-j9kg00qf 4774 13 of of IN cord-022526-j9kg00qf 4774 14 the the DT cord-022526-j9kg00qf 4774 15 root root NN cord-022526-j9kg00qf 4774 16 of of IN cord-022526-j9kg00qf 4774 17 the the DT cord-022526-j9kg00qf 4774 18 cranial cranial JJ cord-022526-j9kg00qf 4774 19 mesenteric mesenteric JJ cord-022526-j9kg00qf 4774 20 artery artery NN cord-022526-j9kg00qf 4774 21 per per IN cord-022526-j9kg00qf 4774 22 rectum rectum NN cord-022526-j9kg00qf 4774 23 . . . cord-022526-j9kg00qf 4775 1 One one PRP cord-022526-j9kg00qf 4775 2 should should MD cord-022526-j9kg00qf 4775 3 consider consider VB cord-022526-j9kg00qf 4775 4 this this DT cord-022526-j9kg00qf 4775 5 disease disease NN cord-022526-j9kg00qf 4775 6 a a DT cord-022526-j9kg00qf 4775 7 differential differential JJ cord-022526-j9kg00qf 4775 8 diagnosis diagnosis NN cord-022526-j9kg00qf 4775 9 in in IN cord-022526-j9kg00qf 4775 10 horses horse NNS cord-022526-j9kg00qf 4775 11 with with IN cord-022526-j9kg00qf 4775 12 a a DT cord-022526-j9kg00qf 4775 13 history history NN cord-022526-j9kg00qf 4775 14 of of IN cord-022526-j9kg00qf 4775 15 inadequate inadequate JJ cord-022526-j9kg00qf 4775 16 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 4775 17 treatment treatment NN cord-022526-j9kg00qf 4775 18 and and CC cord-022526-j9kg00qf 4775 19 the the DT cord-022526-j9kg00qf 4775 20 presence presence NN cord-022526-j9kg00qf 4775 21 of of IN cord-022526-j9kg00qf 4775 22 intermittent intermittent JJ cord-022526-j9kg00qf 4775 23 colic colic NN cord-022526-j9kg00qf 4775 24 that that WDT cord-022526-j9kg00qf 4775 25 is be VBZ cord-022526-j9kg00qf 4775 26 difficult difficult JJ cord-022526-j9kg00qf 4775 27 to to TO cord-022526-j9kg00qf 4775 28 localize localize VB cord-022526-j9kg00qf 4775 29 . . . cord-022526-j9kg00qf 4776 1 Although although IN cord-022526-j9kg00qf 4776 2 one one PRP cord-022526-j9kg00qf 4776 3 should should MD cord-022526-j9kg00qf 4776 4 perform perform VB cord-022526-j9kg00qf 4776 5 fecal fecal JJ cord-022526-j9kg00qf 4776 6 parasite parasite NN cord-022526-j9kg00qf 4776 7 egg egg NN cord-022526-j9kg00qf 4776 8 counts count NNS cord-022526-j9kg00qf 4776 9 , , , cord-022526-j9kg00qf 4776 10 they -PRON- PRP cord-022526-j9kg00qf 4776 11 are be VBP cord-022526-j9kg00qf 4776 12 not not RB cord-022526-j9kg00qf 4776 13 indicative indicative JJ cord-022526-j9kg00qf 4776 14 of of IN cord-022526-j9kg00qf 4776 15 the the DT cord-022526-j9kg00qf 4776 16 degree degree NN cord-022526-j9kg00qf 4776 17 of of IN cord-022526-j9kg00qf 4776 18 parasitic parasitic JJ cord-022526-j9kg00qf 4776 19 infestation infestation NN cord-022526-j9kg00qf 4776 20 . . . cord-022526-j9kg00qf 4777 1 In in IN cord-022526-j9kg00qf 4777 2 addition addition NN cord-022526-j9kg00qf 4777 3 to to IN cord-022526-j9kg00qf 4777 4 routine routine JJ cord-022526-j9kg00qf 4777 5 treatment treatment NN cord-022526-j9kg00qf 4777 6 of of IN cord-022526-j9kg00qf 4777 7 colic colic NN cord-022526-j9kg00qf 4777 8 , , , cord-022526-j9kg00qf 4777 9 dehydration dehydration NN cord-022526-j9kg00qf 4777 10 , , , cord-022526-j9kg00qf 4777 11 and and CC cord-022526-j9kg00qf 4777 12 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4777 13 , , , cord-022526-j9kg00qf 4777 14 medical medical JJ cord-022526-j9kg00qf 4777 15 treatment treatment NN cord-022526-j9kg00qf 4777 16 may may MD cord-022526-j9kg00qf 4777 17 include include VB cord-022526-j9kg00qf 4777 18 aspirin aspirin NN cord-022526-j9kg00qf 4777 19 ( ( -LRB- cord-022526-j9kg00qf 4777 20 20 20 CD cord-022526-j9kg00qf 4777 21 mg mg NNP cord-022526-j9kg00qf 4777 22 / / SYM cord-022526-j9kg00qf 4777 23 kg kg NN cord-022526-j9kg00qf 4777 24 every every DT cord-022526-j9kg00qf 4777 25 24 24 CD cord-022526-j9kg00qf 4777 26 hours hour NNS cord-022526-j9kg00qf 4777 27 ) ) -RRB- cord-022526-j9kg00qf 4777 28 to to TO cord-022526-j9kg00qf 4777 29 decrease decrease VB cord-022526-j9kg00qf 4777 30 thrombosis thrombosis NN cord-022526-j9kg00qf 4777 31 . . . cord-022526-j9kg00qf 4778 1 78 78 CD cord-022526-j9kg00qf 4778 2 Definitive definitive JJ cord-022526-j9kg00qf 4778 3 diagnosis diagnosis NN cord-022526-j9kg00qf 4778 4 requires require VBZ cord-022526-j9kg00qf 4778 5 surgical surgical JJ cord-022526-j9kg00qf 4778 6 exploration exploration NN cord-022526-j9kg00qf 4778 7 . . . cord-022526-j9kg00qf 4779 1 However however RB cord-022526-j9kg00qf 4779 2 , , , cord-022526-j9kg00qf 4779 3 these these DT cord-022526-j9kg00qf 4779 4 cases case NNS cord-022526-j9kg00qf 4779 5 are be VBP cord-022526-j9kg00qf 4779 6 difficult difficult JJ cord-022526-j9kg00qf 4779 7 to to TO cord-022526-j9kg00qf 4779 8 treat treat VB cord-022526-j9kg00qf 4779 9 because because IN cord-022526-j9kg00qf 4779 10 of of IN cord-022526-j9kg00qf 4779 11 the the DT cord-022526-j9kg00qf 4779 12 patchy patchy JJ cord-022526-j9kg00qf 4779 13 distribution distribution NN cord-022526-j9kg00qf 4779 14 of of IN cord-022526-j9kg00qf 4779 15 the the DT cord-022526-j9kg00qf 4779 16 lesions lesion NNS cord-022526-j9kg00qf 4779 17 and and CC cord-022526-j9kg00qf 4779 18 the the DT cord-022526-j9kg00qf 4779 19 possibility possibility NN cord-022526-j9kg00qf 4779 20 of of IN cord-022526-j9kg00qf 4779 21 lesions lesion NNS cord-022526-j9kg00qf 4779 22 extending extend VBG cord-022526-j9kg00qf 4779 23 beyond beyond IN cord-022526-j9kg00qf 4779 24 the the DT cord-022526-j9kg00qf 4779 25 limits limit NNS cord-022526-j9kg00qf 4779 26 of of IN cord-022526-j9kg00qf 4779 27 surgical surgical JJ cord-022526-j9kg00qf 4779 28 resection resection NN cord-022526-j9kg00qf 4779 29 . . . cord-022526-j9kg00qf 4780 1 In in IN cord-022526-j9kg00qf 4780 2 addition addition NN cord-022526-j9kg00qf 4780 3 , , , cord-022526-j9kg00qf 4780 4 further further JJ cord-022526-j9kg00qf 4780 5 infarction infarction NN cord-022526-j9kg00qf 4780 6 may may MD cord-022526-j9kg00qf 4780 7 occur occur VB cord-022526-j9kg00qf 4780 8 following follow VBG cord-022526-j9kg00qf 4780 9 surgery surgery NN cord-022526-j9kg00qf 4780 10 . . . cord-022526-j9kg00qf 4781 1 The the DT cord-022526-j9kg00qf 4781 2 prognosis prognosis NN cord-022526-j9kg00qf 4781 3 is be VBZ cord-022526-j9kg00qf 4781 4 fair fair JJ cord-022526-j9kg00qf 4781 5 for for IN cord-022526-j9kg00qf 4781 6 horses horse NNS cord-022526-j9kg00qf 4781 7 with with IN cord-022526-j9kg00qf 4781 8 intermittent intermittent JJ cord-022526-j9kg00qf 4781 9 mild mild JJ cord-022526-j9kg00qf 4781 10 episodes episode NNS cord-022526-j9kg00qf 4781 11 of of IN cord-022526-j9kg00qf 4781 12 colic colic NN cord-022526-j9kg00qf 4781 13 that that WDT cord-022526-j9kg00qf 4781 14 may may MD cord-022526-j9kg00qf 4781 15 be be VB cord-022526-j9kg00qf 4781 16 amenable amenable JJ cord-022526-j9kg00qf 4781 17 to to IN cord-022526-j9kg00qf 4781 18 medical medical JJ cord-022526-j9kg00qf 4781 19 therapy therapy NN cord-022526-j9kg00qf 4781 20 but but CC cord-022526-j9kg00qf 4781 21 is be VBZ cord-022526-j9kg00qf 4781 22 poor poor JJ cord-022526-j9kg00qf 4781 23 in in IN cord-022526-j9kg00qf 4781 24 horses horse NNS cord-022526-j9kg00qf 4781 25 that that WDT cord-022526-j9kg00qf 4781 26 require require VBP cord-022526-j9kg00qf 4781 27 surgical surgical JJ cord-022526-j9kg00qf 4781 28 intervention intervention NN cord-022526-j9kg00qf 4781 29 . . . cord-022526-j9kg00qf 4782 1 77 77 CD cord-022526-j9kg00qf 4782 2 , , , cord-022526-j9kg00qf 4782 3 78 78 CD cord-022526-j9kg00qf 4782 4 surgical surgical JJ cord-022526-j9kg00qf 4782 5 exploration exploration NN cord-022526-j9kg00qf 4782 6 of of IN cord-022526-j9kg00qf 4782 7 a a DT cord-022526-j9kg00qf 4782 8 horse horse NN cord-022526-j9kg00qf 4782 9 with with IN cord-022526-j9kg00qf 4782 10 on on IN cord-022526-j9kg00qf 4782 11 - - HYPH cord-022526-j9kg00qf 4782 12 going go VBG cord-022526-j9kg00qf 4782 13 intestinal intestinal JJ cord-022526-j9kg00qf 4782 14 injury injury NN cord-022526-j9kg00qf 4782 15 exacerbates exacerbate VBZ cord-022526-j9kg00qf 4782 16 shock shock NN cord-022526-j9kg00qf 4782 17 induced induce VBN cord-022526-j9kg00qf 4782 18 largely largely RB cord-022526-j9kg00qf 4782 19 by by IN cord-022526-j9kg00qf 4782 20 endotoxin endotoxin NN cord-022526-j9kg00qf 4782 21 traversing traverse VBG cord-022526-j9kg00qf 4782 22 damaged damage VBN cord-022526-j9kg00qf 4782 23 mucosa mucosa NN cord-022526-j9kg00qf 4782 24 , , , cord-022526-j9kg00qf 4782 25 and and CC cord-022526-j9kg00qf 4782 26 this this DT cord-022526-j9kg00qf 4782 27 in in IN cord-022526-j9kg00qf 4782 28 turn turn NN cord-022526-j9kg00qf 4782 29 correlates correlate VBZ cord-022526-j9kg00qf 4782 30 with with IN cord-022526-j9kg00qf 4782 31 mortality mortality NN cord-022526-j9kg00qf 4782 32 . . . cord-022526-j9kg00qf 4783 1 3 3 LS cord-022526-j9kg00qf 4784 1 The the DT cord-022526-j9kg00qf 4784 2 initial initial JJ cord-022526-j9kg00qf 4784 3 clinical clinical JJ cord-022526-j9kg00qf 4784 4 step step NN cord-022526-j9kg00qf 4784 5 in in IN cord-022526-j9kg00qf 4784 6 the the DT cord-022526-j9kg00qf 4784 7 workup workup NN cord-022526-j9kg00qf 4784 8 of of IN cord-022526-j9kg00qf 4784 9 horses horse NNS cord-022526-j9kg00qf 4784 10 with with IN cord-022526-j9kg00qf 4784 11 colic colic NN cord-022526-j9kg00qf 4784 12 is be VBZ cord-022526-j9kg00qf 4784 13 taking take VBG cord-022526-j9kg00qf 4784 14 a a DT cord-022526-j9kg00qf 4784 15 thorough thorough JJ cord-022526-j9kg00qf 4784 16 history history NN cord-022526-j9kg00qf 4784 17 . . . cord-022526-j9kg00qf 4785 1 However however RB cord-022526-j9kg00qf 4785 2 , , , cord-022526-j9kg00qf 4785 3 one one PRP cord-022526-j9kg00qf 4785 4 may may MD cord-022526-j9kg00qf 4785 5 have have VB cord-022526-j9kg00qf 4785 6 to to TO cord-022526-j9kg00qf 4785 7 delay delay VB cord-022526-j9kg00qf 4785 8 taking take VBG cord-022526-j9kg00qf 4785 9 a a DT cord-022526-j9kg00qf 4785 10 complete complete JJ cord-022526-j9kg00qf 4785 11 history history NN cord-022526-j9kg00qf 4785 12 until until IN cord-022526-j9kg00qf 4785 13 after after IN cord-022526-j9kg00qf 4785 14 the the DT cord-022526-j9kg00qf 4785 15 physical physical JJ cord-022526-j9kg00qf 4785 16 examination examination NN cord-022526-j9kg00qf 4785 17 and and CC cord-022526-j9kg00qf 4785 18 initial initial JJ cord-022526-j9kg00qf 4785 19 treatment treatment NN cord-022526-j9kg00qf 4785 20 , , , cord-022526-j9kg00qf 4785 21 because because IN cord-022526-j9kg00qf 4785 22 management management NN cord-022526-j9kg00qf 4785 23 of of IN cord-022526-j9kg00qf 4785 24 abdominal abdominal JJ cord-022526-j9kg00qf 4785 25 pain pain NN cord-022526-j9kg00qf 4785 26 may may MD cord-022526-j9kg00qf 4785 27 take take VB cord-022526-j9kg00qf 4785 28 precedence precedence NN cord-022526-j9kg00qf 4785 29 . . . cord-022526-j9kg00qf 4786 1 If if IN cord-022526-j9kg00qf 4786 2 possible possible JJ cord-022526-j9kg00qf 4786 3 , , , cord-022526-j9kg00qf 4786 4 one one PRP cord-022526-j9kg00qf 4786 5 should should MD cord-022526-j9kg00qf 4786 6 obtain obtain VB cord-022526-j9kg00qf 4786 7 the the DT cord-022526-j9kg00qf 4786 8 vital vital JJ cord-022526-j9kg00qf 4786 9 components component NNS cord-022526-j9kg00qf 4786 10 of of IN cord-022526-j9kg00qf 4786 11 the the DT cord-022526-j9kg00qf 4786 12 history history NN cord-022526-j9kg00qf 4786 13 before before IN cord-022526-j9kg00qf 4786 14 examination examination NN cord-022526-j9kg00qf 4786 15 and and CC cord-022526-j9kg00qf 4786 16 treatment treatment NN cord-022526-j9kg00qf 4786 17 : : : cord-022526-j9kg00qf 4786 18 the the DT cord-022526-j9kg00qf 4786 19 duration duration NN cord-022526-j9kg00qf 4786 20 and and CC cord-022526-j9kg00qf 4786 21 severity severity NN cord-022526-j9kg00qf 4786 22 of of IN cord-022526-j9kg00qf 4786 23 colic colic NN cord-022526-j9kg00qf 4786 24 symptoms symptom NNS cord-022526-j9kg00qf 4786 25 , , , cord-022526-j9kg00qf 4786 26 analgesics analgesic NNS cord-022526-j9kg00qf 4786 27 already already RB cord-022526-j9kg00qf 4786 28 administered administer VBN cord-022526-j9kg00qf 4786 29 , , , cord-022526-j9kg00qf 4786 30 and and CC cord-022526-j9kg00qf 4786 31 a a DT cord-022526-j9kg00qf 4786 32 history history NN cord-022526-j9kg00qf 4786 33 of of IN cord-022526-j9kg00qf 4786 34 any any DT cord-022526-j9kg00qf 4786 35 adverse adverse JJ cord-022526-j9kg00qf 4786 36 drug drug NN cord-022526-j9kg00qf 4786 37 reactions reaction NNS cord-022526-j9kg00qf 4786 38 . . . cord-022526-j9kg00qf 4787 1 The the DT cord-022526-j9kg00qf 4787 2 two two CD cord-022526-j9kg00qf 4787 3 most most RBS cord-022526-j9kg00qf 4787 4 critical critical JJ cord-022526-j9kg00qf 4787 5 factors factor NNS cord-022526-j9kg00qf 4787 6 from from IN cord-022526-j9kg00qf 4787 7 a a DT cord-022526-j9kg00qf 4787 8 history history NN cord-022526-j9kg00qf 4787 9 that that WDT cord-022526-j9kg00qf 4787 10 would would MD cord-022526-j9kg00qf 4787 11 support support VB cord-022526-j9kg00qf 4787 12 a a DT cord-022526-j9kg00qf 4787 13 decision decision NN cord-022526-j9kg00qf 4787 14 to to TO cord-022526-j9kg00qf 4787 15 explore explore VB cord-022526-j9kg00qf 4787 16 a a DT cord-022526-j9kg00qf 4787 17 horse horse NN cord-022526-j9kg00qf 4787 18 with with IN cord-022526-j9kg00qf 4787 19 colic colic NN cord-022526-j9kg00qf 4787 20 surgically surgically RB cord-022526-j9kg00qf 4787 21 are be VBP cord-022526-j9kg00qf 4787 22 the the DT cord-022526-j9kg00qf 4787 23 duration duration NN cord-022526-j9kg00qf 4787 24 of of IN cord-022526-j9kg00qf 4787 25 signs sign NNS cord-022526-j9kg00qf 4787 26 and and CC cord-022526-j9kg00qf 4787 27 the the DT cord-022526-j9kg00qf 4787 28 extent extent NN cord-022526-j9kg00qf 4787 29 of of IN cord-022526-j9kg00qf 4787 30 pain pain NN cord-022526-j9kg00qf 4787 31 . . . cord-022526-j9kg00qf 4788 1 One one CD cord-022526-j9kg00qf 4788 2 deduces deduce VBZ cord-022526-j9kg00qf 4788 3 the the DT cord-022526-j9kg00qf 4788 4 latter latter JJ cord-022526-j9kg00qf 4788 5 from from IN cord-022526-j9kg00qf 4788 6 asking ask VBG cord-022526-j9kg00qf 4788 7 the the DT cord-022526-j9kg00qf 4788 8 owner owner NN cord-022526-j9kg00qf 4788 9 about about IN cord-022526-j9kg00qf 4788 10 the the DT cord-022526-j9kg00qf 4788 11 presence presence NN cord-022526-j9kg00qf 4788 12 and and CC cord-022526-j9kg00qf 4788 13 frequency frequency NN cord-022526-j9kg00qf 4788 14 of of IN cord-022526-j9kg00qf 4788 15 pawing paw VBG cord-022526-j9kg00qf 4788 16 , , , cord-022526-j9kg00qf 4788 17 looking look VBG cord-022526-j9kg00qf 4788 18 at at IN cord-022526-j9kg00qf 4788 19 the the DT cord-022526-j9kg00qf 4788 20 flanks flank NNS cord-022526-j9kg00qf 4788 21 , , , cord-022526-j9kg00qf 4788 22 rolling roll VBG cord-022526-j9kg00qf 4788 23 , , , cord-022526-j9kg00qf 4788 24 repeatedly repeatedly RB cord-022526-j9kg00qf 4788 25 going go VBG cord-022526-j9kg00qf 4788 26 down down RP cord-022526-j9kg00qf 4788 27 and and CC cord-022526-j9kg00qf 4788 28 getting get VBG cord-022526-j9kg00qf 4788 29 back back RB cord-022526-j9kg00qf 4788 30 up up RB cord-022526-j9kg00qf 4788 31 , , , cord-022526-j9kg00qf 4788 32 posturing posture VBG cord-022526-j9kg00qf 4788 33 as as IN cord-022526-j9kg00qf 4788 34 if if IN cord-022526-j9kg00qf 4788 35 to to TO cord-022526-j9kg00qf 4788 36 lie lie VB cord-022526-j9kg00qf 4788 37 down down RB cord-022526-j9kg00qf 4788 38 or or CC cord-022526-j9kg00qf 4788 39 urinate urinate VB cord-022526-j9kg00qf 4788 40 , , , cord-022526-j9kg00qf 4788 41 among among IN cord-022526-j9kg00qf 4788 42 other other JJ cord-022526-j9kg00qf 4788 43 clinical clinical JJ cord-022526-j9kg00qf 4788 44 evidence evidence NN cord-022526-j9kg00qf 4788 45 of of IN cord-022526-j9kg00qf 4788 46 pain pain NN cord-022526-j9kg00qf 4788 47 . . . cord-022526-j9kg00qf 4789 1 4 4 CD cord-022526-j9kg00qf 4789 2 Table table NN cord-022526-j9kg00qf 4789 3 13 13 CD cord-022526-j9kg00qf 4789 4 .15 .15 CD cord-022526-j9kg00qf 4789 5 - - SYM cord-022526-j9kg00qf 4789 6 1 1 CD cord-022526-j9kg00qf 4789 7 lists list NNS cord-022526-j9kg00qf 4789 8 other other JJ cord-022526-j9kg00qf 4789 9 important important JJ cord-022526-j9kg00qf 4789 10 components component NNS cord-022526-j9kg00qf 4789 11 of of IN cord-022526-j9kg00qf 4789 12 the the DT cord-022526-j9kg00qf 4789 13 history history NN cord-022526-j9kg00qf 4790 1 one one PRP cord-022526-j9kg00qf 4790 2 should should MD cord-022526-j9kg00qf 4790 3 obtain obtain VB cord-022526-j9kg00qf 4790 4 to to TO cord-022526-j9kg00qf 4790 5 try try VB cord-022526-j9kg00qf 4790 6 to to TO cord-022526-j9kg00qf 4790 7 ascertain ascertain VB cord-022526-j9kg00qf 4790 8 why why WRB cord-022526-j9kg00qf 4790 9 colic colic NN cord-022526-j9kg00qf 4790 10 has have VBZ cord-022526-j9kg00qf 4790 11 occurred occur VBN cord-022526-j9kg00qf 4790 12 . . . cord-022526-j9kg00qf 4791 1 Just just RB cord-022526-j9kg00qf 4791 2 as as IN cord-022526-j9kg00qf 4791 3 the the DT cord-022526-j9kg00qf 4791 4 history history NN cord-022526-j9kg00qf 4791 5 necessarily necessarily RB cord-022526-j9kg00qf 4791 6 may may MD cord-022526-j9kg00qf 4791 7 need need VB cord-022526-j9kg00qf 4791 8 to to TO cord-022526-j9kg00qf 4791 9 be be VB cord-022526-j9kg00qf 4791 10 brief brief JJ cord-022526-j9kg00qf 4791 11 to to TO cord-022526-j9kg00qf 4791 12 allow allow VB cord-022526-j9kg00qf 4791 13 rapid rapid JJ cord-022526-j9kg00qf 4791 14 treatment treatment NN cord-022526-j9kg00qf 4791 15 of of IN cord-022526-j9kg00qf 4791 16 colic colic NN cord-022526-j9kg00qf 4791 17 , , , cord-022526-j9kg00qf 4791 18 so so CC cord-022526-j9kg00qf 4791 19 the the DT cord-022526-j9kg00qf 4791 20 clinician clinician NN cord-022526-j9kg00qf 4791 21 must must MD cord-022526-j9kg00qf 4791 22 be be VB cord-022526-j9kg00qf 4791 23 able able JJ cord-022526-j9kg00qf 4791 24 to to TO cord-022526-j9kg00qf 4791 25 alter alter VB cord-022526-j9kg00qf 4791 26 the the DT cord-022526-j9kg00qf 4791 27 extent extent NN cord-022526-j9kg00qf 4791 28 of of IN cord-022526-j9kg00qf 4791 29 the the DT cord-022526-j9kg00qf 4791 30 physical physical JJ cord-022526-j9kg00qf 4791 31 examination examination NN cord-022526-j9kg00qf 4791 32 to to TO cord-022526-j9kg00qf 4791 33 treat treat VB cord-022526-j9kg00qf 4791 34 the the DT cord-022526-j9kg00qf 4791 35 horse horse NN cord-022526-j9kg00qf 4791 36 in in IN cord-022526-j9kg00qf 4791 37 a a DT cord-022526-j9kg00qf 4791 38 timely timely JJ cord-022526-j9kg00qf 4791 39 fashion fashion NN cord-022526-j9kg00qf 4791 40 . . . cord-022526-j9kg00qf 4792 1 The the DT cord-022526-j9kg00qf 4792 2 most most RBS cord-022526-j9kg00qf 4792 3 critical critical JJ cord-022526-j9kg00qf 4792 4 examination examination NN cord-022526-j9kg00qf 4792 5 finding finding NN cord-022526-j9kg00qf 4792 6 is be VBZ cord-022526-j9kg00qf 4792 7 the the DT cord-022526-j9kg00qf 4792 8 heart heart NN cord-022526-j9kg00qf 4792 9 rate rate NN cord-022526-j9kg00qf 4792 10 of of IN cord-022526-j9kg00qf 4792 11 the the DT cord-022526-j9kg00qf 4792 12 horse horse NN cord-022526-j9kg00qf 4792 13 , , , cord-022526-j9kg00qf 4792 14 because because IN cord-022526-j9kg00qf 4792 15 it -PRON- PRP cord-022526-j9kg00qf 4792 16 provides provide VBZ cord-022526-j9kg00qf 4792 17 an an DT cord-022526-j9kg00qf 4792 18 excellent excellent JJ cord-022526-j9kg00qf 4792 19 assessment assessment NN cord-022526-j9kg00qf 4792 20 of of IN cord-022526-j9kg00qf 4792 21 the the DT cord-022526-j9kg00qf 4792 22 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 4792 23 status status NN cord-022526-j9kg00qf 4792 24 of of IN cord-022526-j9kg00qf 4792 25 the the DT cord-022526-j9kg00qf 4792 26 horse horse NN cord-022526-j9kg00qf 4792 27 . . . cord-022526-j9kg00qf 4793 1 4 4 LS cord-022526-j9kg00qf 4794 1 The the DT cord-022526-j9kg00qf 4794 2 heart heart NN cord-022526-j9kg00qf 4794 3 rate rate NN cord-022526-j9kg00qf 4794 4 is be VBZ cord-022526-j9kg00qf 4794 5 likely likely RB cord-022526-j9kg00qf 4794 6 the the DT cord-022526-j9kg00qf 4794 7 single single JJ cord-022526-j9kg00qf 4794 8 most most RBS cord-022526-j9kg00qf 4794 9 reliable reliable JJ cord-022526-j9kg00qf 4794 10 predictor predictor NN cord-022526-j9kg00qf 4794 11 of of IN cord-022526-j9kg00qf 4794 12 the the DT cord-022526-j9kg00qf 4794 13 need need NN cord-022526-j9kg00qf 4794 14 for for IN cord-022526-j9kg00qf 4794 15 surgery surgery NN cord-022526-j9kg00qf 4794 16 and and CC cord-022526-j9kg00qf 4794 17 survival survival NN cord-022526-j9kg00qf 4794 18 . . . cord-022526-j9kg00qf 4795 1 4 4 LS cord-022526-j9kg00qf 4795 2 , , , cord-022526-j9kg00qf 4795 3 5 5 CD cord-022526-j9kg00qf 4796 1 Because because IN cord-022526-j9kg00qf 4796 2 analgesics analgesic NNS cord-022526-j9kg00qf 4796 3 can can MD cord-022526-j9kg00qf 4796 4 alter alter VB cord-022526-j9kg00qf 4796 5 the the DT cord-022526-j9kg00qf 4796 6 heart heart NN cord-022526-j9kg00qf 4796 7 rate rate NN cord-022526-j9kg00qf 4796 8 dramatically dramatically RB cord-022526-j9kg00qf 4796 9 , , , cord-022526-j9kg00qf 4796 10 if if IN cord-022526-j9kg00qf 4796 11 possible possible JJ cord-022526-j9kg00qf 4796 12 , , , cord-022526-j9kg00qf 4796 13 one one PRP cord-022526-j9kg00qf 4796 14 should should MD cord-022526-j9kg00qf 4796 15 obtain obtain VB cord-022526-j9kg00qf 4796 16 the the DT cord-022526-j9kg00qf 4796 17 heart heart NN cord-022526-j9kg00qf 4796 18 rate rate NN cord-022526-j9kg00qf 4796 19 before before IN cord-022526-j9kg00qf 4796 20 administering administer VBG cord-022526-j9kg00qf 4796 21 analgesics analgesic NNS cord-022526-j9kg00qf 4796 22 . . . cord-022526-j9kg00qf 4797 1 Other other JJ cord-022526-j9kg00qf 4797 2 components component NNS cord-022526-j9kg00qf 4797 3 of of IN cord-022526-j9kg00qf 4797 4 the the DT cord-022526-j9kg00qf 4797 5 examination examination NN cord-022526-j9kg00qf 4797 6 are be VBP cord-022526-j9kg00qf 4797 7 designed design VBN cord-022526-j9kg00qf 4797 8 specifically specifically RB cord-022526-j9kg00qf 4797 9 to to TO cord-022526-j9kg00qf 4797 10 gather gather VB cord-022526-j9kg00qf 4797 11 information information NN cord-022526-j9kg00qf 4797 12 about about IN cord-022526-j9kg00qf 4797 13 the the DT cord-022526-j9kg00qf 4797 14 cardiopulmonary cardiopulmonary JJ cord-022526-j9kg00qf 4797 15 status status NN cord-022526-j9kg00qf 4797 16 of of IN cord-022526-j9kg00qf 4797 17 the the DT cord-022526-j9kg00qf 4797 18 horse horse NN cord-022526-j9kg00qf 4797 19 ( ( -LRB- cord-022526-j9kg00qf 4797 20 quality quality NN cord-022526-j9kg00qf 4797 21 of of IN cord-022526-j9kg00qf 4797 22 the the DT cord-022526-j9kg00qf 4797 23 pulse pulse NN cord-022526-j9kg00qf 4797 24 , , , cord-022526-j9kg00qf 4797 25 mucous mucous JJ cord-022526-j9kg00qf 4797 26 membrane membrane NN cord-022526-j9kg00qf 4797 27 color color NN cord-022526-j9kg00qf 4797 28 , , , cord-022526-j9kg00qf 4797 29 capillary capillary JJ cord-022526-j9kg00qf 4797 30 refill refill NN cord-022526-j9kg00qf 4797 31 time time NN cord-022526-j9kg00qf 4797 32 , , , cord-022526-j9kg00qf 4797 33 respiratory respiratory JJ cord-022526-j9kg00qf 4797 34 rate rate NN cord-022526-j9kg00qf 4797 35 , , , cord-022526-j9kg00qf 4797 36 and and CC cord-022526-j9kg00qf 4797 37 full full JJ cord-022526-j9kg00qf 4797 38 auscultation auscultation NN cord-022526-j9kg00qf 4797 39 of of IN cord-022526-j9kg00qf 4797 40 the the DT cord-022526-j9kg00qf 4797 41 chest chest NN cord-022526-j9kg00qf 4797 42 ) ) -RRB- cord-022526-j9kg00qf 4797 43 , , , cord-022526-j9kg00qf 4797 44 and and CC cord-022526-j9kg00qf 4797 45 the the DT cord-022526-j9kg00qf 4797 46 nature nature NN cord-022526-j9kg00qf 4797 47 of of IN cord-022526-j9kg00qf 4797 48 the the DT cord-022526-j9kg00qf 4797 49 intestinal intestinal JJ cord-022526-j9kg00qf 4797 50 obstruction obstruction NN cord-022526-j9kg00qf 4797 51 ( ( -LRB- cord-022526-j9kg00qf 4797 52 auscultation auscultation NN cord-022526-j9kg00qf 4797 53 of of IN cord-022526-j9kg00qf 4797 54 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4797 55 sounds sound NNS cord-022526-j9kg00qf 4797 56 , , , cord-022526-j9kg00qf 4797 57 per per IN cord-022526-j9kg00qf 4797 58 rectal rectal JJ cord-022526-j9kg00qf 4797 59 palpation palpation NN cord-022526-j9kg00qf 4797 60 of of IN cord-022526-j9kg00qf 4797 61 the the DT cord-022526-j9kg00qf 4797 62 abdomen abdomen NN cord-022526-j9kg00qf 4797 63 , , , cord-022526-j9kg00qf 4797 64 and and CC cord-022526-j9kg00qf 4797 65 presence presence NN cord-022526-j9kg00qf 4797 66 of of IN cord-022526-j9kg00qf 4797 67 nasogastric nasogastric NN cord-022526-j9kg00qf 4797 68 reflux reflux NN cord-022526-j9kg00qf 4797 69 ) ) -RRB- cord-022526-j9kg00qf 4797 70 . . . cord-022526-j9kg00qf 4798 1 Although although IN cord-022526-j9kg00qf 4798 2 classic classic JJ cord-022526-j9kg00qf 4798 3 presentations presentation NNS cord-022526-j9kg00qf 4798 4 exist exist VBP cord-022526-j9kg00qf 4798 5 for for IN cord-022526-j9kg00qf 4798 6 horses horse NNS cord-022526-j9kg00qf 4798 7 with with IN cord-022526-j9kg00qf 4798 8 obstructions obstruction NNS cord-022526-j9kg00qf 4798 9 of of IN cord-022526-j9kg00qf 4798 10 the the DT cord-022526-j9kg00qf 4798 11 small small JJ cord-022526-j9kg00qf 4798 12 or or CC cord-022526-j9kg00qf 4798 13 large large JJ cord-022526-j9kg00qf 4798 14 intestine intestine NN cord-022526-j9kg00qf 4798 15 ( ( -LRB- cord-022526-j9kg00qf 4798 16 Table Table NNP cord-022526-j9kg00qf 4798 17 _SP cord-022526-j9kg00qf 4798 18 13 13 CD cord-022526-j9kg00qf 4798 19 . . . cord-022526-j9kg00qf 4798 20 _SP cord-022526-j9kg00qf 4799 1 Clinical clinical JJ cord-022526-j9kg00qf 4799 2 management management NN cord-022526-j9kg00qf 4799 3 of of IN cord-022526-j9kg00qf 4799 4 colic colic NN cord-022526-j9kg00qf 4799 5 is be VBZ cord-022526-j9kg00qf 4799 6 distinctly distinctly RB cord-022526-j9kg00qf 4799 7 different different JJ cord-022526-j9kg00qf 4799 8 from from IN cord-022526-j9kg00qf 4799 9 management management NN cord-022526-j9kg00qf 4799 10 of of IN cord-022526-j9kg00qf 4799 11 many many JJ cord-022526-j9kg00qf 4799 12 other other JJ cord-022526-j9kg00qf 4799 13 clinical clinical JJ cord-022526-j9kg00qf 4799 14 syndromes syndrome NNS cord-022526-j9kg00qf 4799 15 because because IN cord-022526-j9kg00qf 4799 16 the the DT cord-022526-j9kg00qf 4799 17 initial initial JJ cord-022526-j9kg00qf 4799 18 focus focus NN cord-022526-j9kg00qf 4799 19 is be VBZ cord-022526-j9kg00qf 4799 20 often often RB cord-022526-j9kg00qf 4799 21 not not RB cord-022526-j9kg00qf 4799 22 on on IN cord-022526-j9kg00qf 4799 23 defining define VBG cord-022526-j9kg00qf 4799 24 the the DT cord-022526-j9kg00qf 4799 25 definitive definitive JJ cord-022526-j9kg00qf 4799 26 diagnosis diagnosis NN cord-022526-j9kg00qf 4799 27 but but CC cord-022526-j9kg00qf 4799 28 rather rather RB cord-022526-j9kg00qf 4799 29 on on IN cord-022526-j9kg00qf 4799 30 deciding decide VBG cord-022526-j9kg00qf 4799 31 whether whether IN cord-022526-j9kg00qf 4799 32 a a DT cord-022526-j9kg00qf 4799 33 horse horse NN cord-022526-j9kg00qf 4799 34 requires require VBZ cord-022526-j9kg00qf 4799 35 surgical surgical JJ cord-022526-j9kg00qf 4799 36 exploration exploration NN cord-022526-j9kg00qf 4799 37 . . . cord-022526-j9kg00qf 4800 1 Therefore therefore RB cord-022526-j9kg00qf 4800 2 the the DT cord-022526-j9kg00qf 4800 3 clinician clinician NN cord-022526-j9kg00qf 4800 4 must must MD cord-022526-j9kg00qf 4800 5 collect collect VB cord-022526-j9kg00qf 4800 6 historical historical JJ cord-022526-j9kg00qf 4800 7 , , , cord-022526-j9kg00qf 4800 8 physical physical JJ cord-022526-j9kg00qf 4800 9 examination examination NN cord-022526-j9kg00qf 4800 10 , , , cord-022526-j9kg00qf 4800 11 and and CC cord-022526-j9kg00qf 4800 12 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 4800 13 information information NN cord-022526-j9kg00qf 4800 14 and and CC cord-022526-j9kg00qf 4800 15 make make VB cord-022526-j9kg00qf 4800 16 a a DT cord-022526-j9kg00qf 4800 17 decision decision NN cord-022526-j9kg00qf 4800 18 whether whether IN cord-022526-j9kg00qf 4800 19 these these DT cord-022526-j9kg00qf 4800 20 findings finding NNS cord-022526-j9kg00qf 4800 21 warrant warrant VBP cord-022526-j9kg00qf 4800 22 medical medical JJ cord-022526-j9kg00qf 4800 23 management management NN cord-022526-j9kg00qf 4800 24 or or CC cord-022526-j9kg00qf 4800 25 whether whether IN cord-022526-j9kg00qf 4800 26 to to TO cord-022526-j9kg00qf 4800 27 perform perform VB cord-022526-j9kg00qf 4800 28 surgical surgical JJ cord-022526-j9kg00qf 4800 29 exploration exploration NN cord-022526-j9kg00qf 4800 30 of of IN cord-022526-j9kg00qf 4800 31 the the DT cord-022526-j9kg00qf 4800 32 abdomen abdomen NN cord-022526-j9kg00qf 4800 33 because because IN cord-022526-j9kg00qf 4800 34 of of IN cord-022526-j9kg00qf 4800 35 a a DT cord-022526-j9kg00qf 4800 36 suspected suspect VBN cord-022526-j9kg00qf 4800 37 obstructive obstructive JJ cord-022526-j9kg00qf 4800 38 or or CC cord-022526-j9kg00qf 4800 39 ischemic ischemic JJ cord-022526-j9kg00qf 4800 40 lesion lesion NN cord-022526-j9kg00qf 4800 41 . . . cord-022526-j9kg00qf 4801 1 For for IN cord-022526-j9kg00qf 4801 2 example example NN cord-022526-j9kg00qf 4801 3 , , , cord-022526-j9kg00qf 4801 4 one one PRP cord-022526-j9kg00qf 4801 5 may may MD cord-022526-j9kg00qf 4801 6 examine examine VB cord-022526-j9kg00qf 4801 7 a a DT cord-022526-j9kg00qf 4801 8 horse horse NN cord-022526-j9kg00qf 4801 9 with with IN cord-022526-j9kg00qf 4801 10 signs sign NNS cord-022526-j9kg00qf 4801 11 of of IN cord-022526-j9kg00qf 4801 12 severe severe JJ cord-022526-j9kg00qf 4801 13 abdominal abdominal JJ cord-022526-j9kg00qf 4801 14 pain pain NN cord-022526-j9kg00qf 4801 15 , , , cord-022526-j9kg00qf 4801 16 poor poor JJ cord-022526-j9kg00qf 4801 17 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 4801 18 status status NN cord-022526-j9kg00qf 4801 19 , , , cord-022526-j9kg00qf 4801 20 and and CC cord-022526-j9kg00qf 4801 21 abdominal abdominal JJ cord-022526-j9kg00qf 4801 22 distention distention NN cord-022526-j9kg00qf 4801 23 that that WDT cord-022526-j9kg00qf 4801 24 may may MD cord-022526-j9kg00qf 4801 25 be be VB cord-022526-j9kg00qf 4801 26 compatible compatible JJ cord-022526-j9kg00qf 4801 27 with with IN cord-022526-j9kg00qf 4801 28 an an DT cord-022526-j9kg00qf 4801 29 extensive extensive JJ cord-022526-j9kg00qf 4801 30 list list NN cord-022526-j9kg00qf 4801 31 of of IN cord-022526-j9kg00qf 4801 32 differential differential JJ cord-022526-j9kg00qf 4801 33 diagnoses diagnosis NNS cord-022526-j9kg00qf 4801 34 but but CC cord-022526-j9kg00qf 4801 35 that that IN cord-022526-j9kg00qf 4801 36 more more RBR cord-022526-j9kg00qf 4801 37 importantly importantly RB cord-022526-j9kg00qf 4801 38 indicate indicate VBP cord-022526-j9kg00qf 4801 39 the the DT cord-022526-j9kg00qf 4801 40 need need NN cord-022526-j9kg00qf 4801 41 for for IN cord-022526-j9kg00qf 4801 42 abdominal abdominal JJ cord-022526-j9kg00qf 4801 43 exploration exploration NN cord-022526-j9kg00qf 4801 44 to to TO cord-022526-j9kg00qf 4801 45 minimize minimize VB cord-022526-j9kg00qf 4801 46 the the DT cord-022526-j9kg00qf 4801 47 extent extent NN cord-022526-j9kg00qf 4801 48 of of IN cord-022526-j9kg00qf 4801 49 intestinal intestinal JJ cord-022526-j9kg00qf 4801 50 injury injury NN cord-022526-j9kg00qf 4801 51 . . . cord-022526-j9kg00qf 4802 1 The the DT cord-022526-j9kg00qf 4802 2 speed speed NN cord-022526-j9kg00qf 4802 3 with with IN cord-022526-j9kg00qf 4802 4 which which WDT cord-022526-j9kg00qf 4802 5 one one PRP cord-022526-j9kg00qf 4802 6 can can MD cord-022526-j9kg00qf 4802 7 make make VB cord-022526-j9kg00qf 4802 8 this this DT cord-022526-j9kg00qf 4802 9 clinical clinical JJ cord-022526-j9kg00qf 4802 10 decision decision NN cord-022526-j9kg00qf 4802 11 has have VBZ cord-022526-j9kg00qf 4802 12 a a DT cord-022526-j9kg00qf 4802 13 tremendous tremendous JJ cord-022526-j9kg00qf 4802 14 effect effect NN cord-022526-j9kg00qf 4802 15 on on IN cord-022526-j9kg00qf 4802 16 the the DT cord-022526-j9kg00qf 4802 17 well well NN cord-022526-j9kg00qf 4802 18 - - HYPH cord-022526-j9kg00qf 4802 19 being being NN cord-022526-j9kg00qf 4802 20 of of IN cord-022526-j9kg00qf 4802 21 the the DT cord-022526-j9kg00qf 4802 22 patient patient NN cord-022526-j9kg00qf 4802 23 , , , cord-022526-j9kg00qf 4802 24 1,2 1,2 CD cord-022526-j9kg00qf 4802 25 because because IN cord-022526-j9kg00qf 4802 26 delaying delay VBG cord-022526-j9kg00qf 4802 27 gastric gastric JJ cord-022526-j9kg00qf 4802 28 fluid fluid JJ cord-022526-j9kg00qf 4802 29 accumulation accumulation NN cord-022526-j9kg00qf 4802 30 because because IN cord-022526-j9kg00qf 4802 31 of of IN cord-022526-j9kg00qf 4802 32 direct direct JJ cord-022526-j9kg00qf 4802 33 compression compression NN cord-022526-j9kg00qf 4802 34 of of IN cord-022526-j9kg00qf 4802 35 the the DT cord-022526-j9kg00qf 4802 36 small small JJ cord-022526-j9kg00qf 4802 37 intestine intestine NN cord-022526-j9kg00qf 4802 38 by by IN cord-022526-j9kg00qf 4802 39 distended distended JJ cord-022526-j9kg00qf 4802 40 colon colon NN cord-022526-j9kg00qf 4802 41 or or CC cord-022526-j9kg00qf 4802 42 via via IN cord-022526-j9kg00qf 4802 43 tension tension NN cord-022526-j9kg00qf 4802 44 on on IN cord-022526-j9kg00qf 4802 45 the the DT cord-022526-j9kg00qf 4802 46 duodenocolic duodenocolic NN cord-022526-j9kg00qf 4802 47 ligament ligament NN cord-022526-j9kg00qf 4802 48 . . . cord-022526-j9kg00qf 4803 1 The the DT cord-022526-j9kg00qf 4803 2 most most RBS cord-022526-j9kg00qf 4803 3 useful useful JJ cord-022526-j9kg00qf 4803 4 diagnostic diagnostic JJ cord-022526-j9kg00qf 4803 5 test test NN cord-022526-j9kg00qf 4803 6 for for IN cord-022526-j9kg00qf 4803 7 determining determine VBG cord-022526-j9kg00qf 4803 8 the the DT cord-022526-j9kg00qf 4803 9 type type NN cord-022526-j9kg00qf 4803 10 of of IN cord-022526-j9kg00qf 4803 11 intestinal intestinal JJ cord-022526-j9kg00qf 4803 12 obstruction obstruction NN cord-022526-j9kg00qf 4803 13 is be VBZ cord-022526-j9kg00qf 4803 14 rectal rectal JJ cord-022526-j9kg00qf 4803 15 palpation palpation NN cord-022526-j9kg00qf 4803 16 of of IN cord-022526-j9kg00qf 4803 17 the the DT cord-022526-j9kg00qf 4803 18 abdomen abdomen NN cord-022526-j9kg00qf 4803 19 . . . cord-022526-j9kg00qf 4804 1 4 4 LS cord-022526-j9kg00qf 4805 1 However however RB cord-022526-j9kg00qf 4805 2 , , , cord-022526-j9kg00qf 4805 3 one one PRP cord-022526-j9kg00qf 4805 4 can can MD cord-022526-j9kg00qf 4805 5 reach reach VB cord-022526-j9kg00qf 4805 6 only only RB cord-022526-j9kg00qf 4805 7 approximately approximately RB cord-022526-j9kg00qf 4805 8 one one CD cord-022526-j9kg00qf 4805 9 third third NN cord-022526-j9kg00qf 4805 10 of of IN cord-022526-j9kg00qf 4805 11 the the DT cord-022526-j9kg00qf 4805 12 abdomen abdomen NN cord-022526-j9kg00qf 4805 13 via via IN cord-022526-j9kg00qf 4805 14 the the DT cord-022526-j9kg00qf 4805 15 rectum rectum NN cord-022526-j9kg00qf 4805 16 , , , cord-022526-j9kg00qf 4805 17 and and CC cord-022526-j9kg00qf 4805 18 this this DT cord-022526-j9kg00qf 4805 19 percentage percentage NN cord-022526-j9kg00qf 4805 20 may may MD cord-022526-j9kg00qf 4805 21 be be VB cord-022526-j9kg00qf 4805 22 substantially substantially RB cord-022526-j9kg00qf 4805 23 less less JJR cord-022526-j9kg00qf 4805 24 in in IN cord-022526-j9kg00qf 4805 25 large large JJ cord-022526-j9kg00qf 4805 26 horses horse NNS cord-022526-j9kg00qf 4805 27 or or CC cord-022526-j9kg00qf 4805 28 heavily heavily RB cord-022526-j9kg00qf 4805 29 pregnant pregnant JJ cord-022526-j9kg00qf 4805 30 horses horse NNS cord-022526-j9kg00qf 4805 31 . . . cord-022526-j9kg00qf 4806 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 4806 2 , , , cord-022526-j9kg00qf 4806 3 attempting attempt VBG cord-022526-j9kg00qf 4806 4 to to TO cord-022526-j9kg00qf 4806 5 determine determine VB cord-022526-j9kg00qf 4806 6 the the DT cord-022526-j9kg00qf 4806 7 type type NN cord-022526-j9kg00qf 4806 8 of of IN cord-022526-j9kg00qf 4806 9 obstruction obstruction NN cord-022526-j9kg00qf 4806 10 present present JJ cord-022526-j9kg00qf 4806 11 ( ( -LRB- cord-022526-j9kg00qf 4806 12 small small JJ cord-022526-j9kg00qf 4806 13 intestine intestine NN cord-022526-j9kg00qf 4806 14 versus versus IN cord-022526-j9kg00qf 4806 15 large large JJ cord-022526-j9kg00qf 4806 16 intestine intestine NN cord-022526-j9kg00qf 4806 17 , , , cord-022526-j9kg00qf 4806 18 and and CC cord-022526-j9kg00qf 4806 19 simple simple JJ cord-022526-j9kg00qf 4806 20 obstruction obstruction NN cord-022526-j9kg00qf 4806 21 versus versus IN cord-022526-j9kg00qf 4806 22 strangulating strangulating JJ cord-022526-j9kg00qf 4806 23 obstruction obstruction NN cord-022526-j9kg00qf 4806 24 ) ) -RRB- cord-022526-j9kg00qf 4806 25 is be VBZ cord-022526-j9kg00qf 4806 26 worthwhile worthwhile JJ cord-022526-j9kg00qf 4806 27 ; ; : cord-022526-j9kg00qf 4806 28 this this DT cord-022526-j9kg00qf 4806 29 information information NN cord-022526-j9kg00qf 4806 30 directly directly RB cord-022526-j9kg00qf 4806 31 affects affect VBZ cord-022526-j9kg00qf 4806 32 prognosis prognosis NN cord-022526-j9kg00qf 4806 33 . . . cord-022526-j9kg00qf 4807 1 In in IN cord-022526-j9kg00qf 4807 2 one one CD cord-022526-j9kg00qf 4807 3 study study NN cord-022526-j9kg00qf 4807 4 , , , cord-022526-j9kg00qf 4807 5 interns intern NNS cord-022526-j9kg00qf 4807 6 and and CC cord-022526-j9kg00qf 4807 7 residents resident NNS cord-022526-j9kg00qf 4807 8 at at IN cord-022526-j9kg00qf 4807 9 a a DT cord-022526-j9kg00qf 4807 10 veterinary veterinary JJ cord-022526-j9kg00qf 4807 11 teaching teaching NN cord-022526-j9kg00qf 4807 12 hospital hospital NN cord-022526-j9kg00qf 4807 13 were be VBD cord-022526-j9kg00qf 4807 14 able able JJ cord-022526-j9kg00qf 4807 15 to to TO cord-022526-j9kg00qf 4807 16 predict predict VB cord-022526-j9kg00qf 4807 17 the the DT cord-022526-j9kg00qf 4807 18 type type NN cord-022526-j9kg00qf 4807 19 of of IN cord-022526-j9kg00qf 4807 20 lesion lesion NN cord-022526-j9kg00qf 4807 21 with with IN cord-022526-j9kg00qf 4807 22 a a DT cord-022526-j9kg00qf 4807 23 specificity specificity NN cord-022526-j9kg00qf 4807 24 exceeding exceed VBG cord-022526-j9kg00qf 4807 25 90 90 CD cord-022526-j9kg00qf 4807 26 % % NN cord-022526-j9kg00qf 4807 27 . . . cord-022526-j9kg00qf 4808 1 6 6 CD cord-022526-j9kg00qf 4808 2 Findings finding NNS cord-022526-j9kg00qf 4808 3 from from IN cord-022526-j9kg00qf 4808 4 palpation palpation NN cord-022526-j9kg00qf 4808 5 are be VBP cord-022526-j9kg00qf 4808 6 helpful helpful JJ cord-022526-j9kg00qf 4808 7 in in IN cord-022526-j9kg00qf 4808 8 educating educate VBG cord-022526-j9kg00qf 4808 9 the the DT cord-022526-j9kg00qf 4808 10 client client NN cord-022526-j9kg00qf 4808 11 about about IN cord-022526-j9kg00qf 4808 12 the the DT cord-022526-j9kg00qf 4808 13 potential potential JJ cord-022526-j9kg00qf 4808 14 findings finding NNS cord-022526-j9kg00qf 4808 15 in in IN cord-022526-j9kg00qf 4808 16 surgery surgery NN cord-022526-j9kg00qf 4808 17 and and CC cord-022526-j9kg00qf 4808 18 the the DT cord-022526-j9kg00qf 4808 19 likelihood likelihood NN cord-022526-j9kg00qf 4808 20 of of IN cord-022526-j9kg00qf 4808 21 survival survival NN cord-022526-j9kg00qf 4808 22 for for IN cord-022526-j9kg00qf 4808 23 the the DT cord-022526-j9kg00qf 4808 24 horse horse NN cord-022526-j9kg00qf 4808 25 . . . cord-022526-j9kg00qf 4809 1 Before before IN cord-022526-j9kg00qf 4809 2 considering consider VBG cord-022526-j9kg00qf 4809 3 how how WRB cord-022526-j9kg00qf 4809 4 to to TO cord-022526-j9kg00qf 4809 5 manage manage VB cord-022526-j9kg00qf 4809 6 signs sign NNS cord-022526-j9kg00qf 4809 7 of of IN cord-022526-j9kg00qf 4809 8 colic colic NN cord-022526-j9kg00qf 4809 9 , , , cord-022526-j9kg00qf 4809 10 one one PRP cord-022526-j9kg00qf 4809 11 should should MD cord-022526-j9kg00qf 4809 12 remember remember VB cord-022526-j9kg00qf 4809 13 that that IN cord-022526-j9kg00qf 4809 14 such such JJ cord-022526-j9kg00qf 4809 15 signs sign NNS cord-022526-j9kg00qf 4809 16 are be VBP cord-022526-j9kg00qf 4809 17 poorly poorly RB cord-022526-j9kg00qf 4809 18 localized localize VBN cord-022526-j9kg00qf 4809 19 . . . cord-022526-j9kg00qf 4810 1 Therefore therefore RB cord-022526-j9kg00qf 4810 2 although although IN cord-022526-j9kg00qf 4810 3 colic colic NN cord-022526-j9kg00qf 4810 4 is be VBZ cord-022526-j9kg00qf 4810 5 most most RBS cord-022526-j9kg00qf 4810 6 frequently frequently RB cord-022526-j9kg00qf 4810 7 associated associate VBN cord-022526-j9kg00qf 4810 8 with with IN cord-022526-j9kg00qf 4810 9 intestinal intestinal JJ cord-022526-j9kg00qf 4810 10 disease disease NN cord-022526-j9kg00qf 4810 11 , , , cord-022526-j9kg00qf 4810 12 one one PRP cord-022526-j9kg00qf 4810 13 should should MD cord-022526-j9kg00qf 4810 14 consider consider VB cord-022526-j9kg00qf 4810 15 dysfunction dysfunction NN cord-022526-j9kg00qf 4810 16 of of IN cord-022526-j9kg00qf 4810 17 other other JJ cord-022526-j9kg00qf 4810 18 organ organ NN cord-022526-j9kg00qf 4810 19 systems system NNS cord-022526-j9kg00qf 4810 20 , , , cord-022526-j9kg00qf 4810 21 including include VBG cord-022526-j9kg00qf 4810 22 urinary urinary JJ cord-022526-j9kg00qf 4810 23 obstruction obstruction NN cord-022526-j9kg00qf 4810 24 , , , cord-022526-j9kg00qf 4810 25 7,8 7,8 CD cord-022526-j9kg00qf 4810 26 biliary biliary JJ cord-022526-j9kg00qf 4810 27 obstruction obstruction NN cord-022526-j9kg00qf 4810 28 , , , cord-022526-j9kg00qf 4810 29 9 9 CD cord-022526-j9kg00qf 4810 30 uterine uterine JJ cord-022526-j9kg00qf 4810 31 torsion torsion NN cord-022526-j9kg00qf 4810 32 or or CC cord-022526-j9kg00qf 4810 33 tears tear NNS cord-022526-j9kg00qf 4810 34 , , , cord-022526-j9kg00qf 4810 35 10,11 10,11 CD cord-022526-j9kg00qf 4810 36 ovarian ovarian JJ cord-022526-j9kg00qf 4810 37 artery artery NN cord-022526-j9kg00qf 4810 38 hemorrhage hemorrhage NN cord-022526-j9kg00qf 4810 39 , , , cord-022526-j9kg00qf 4810 40 10 10 CD cord-022526-j9kg00qf 4810 41 and and CC cord-022526-j9kg00qf 4810 42 neurologic neurologic JJ cord-022526-j9kg00qf 4810 43 disease disease NN cord-022526-j9kg00qf 4810 44 as as IN cord-022526-j9kg00qf 4810 45 differential differential JJ cord-022526-j9kg00qf 4810 46 diagnoses diagnosis NNS cord-022526-j9kg00qf 4810 47 . . . cord-022526-j9kg00qf 4811 1 12 12 CD cord-022526-j9kg00qf 4812 1 However however RB cord-022526-j9kg00qf 4812 2 , , , cord-022526-j9kg00qf 4812 3 the the DT cord-022526-j9kg00qf 4812 4 duration duration NN cord-022526-j9kg00qf 4812 5 and and CC cord-022526-j9kg00qf 4812 6 severity severity NN cord-022526-j9kg00qf 4812 7 of of IN cord-022526-j9kg00qf 4812 8 colic colic NN cord-022526-j9kg00qf 4812 9 _SP cord-022526-j9kg00qf 4813 1 The the DT cord-022526-j9kg00qf 4813 2 most most RBS cord-022526-j9kg00qf 4813 3 immediately immediately RB cord-022526-j9kg00qf 4813 4 useful useful JJ cord-022526-j9kg00qf 4813 5 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 4813 6 information information NN cord-022526-j9kg00qf 4813 7 in in IN cord-022526-j9kg00qf 4813 8 horses horse NNS cord-022526-j9kg00qf 4813 9 with with IN cord-022526-j9kg00qf 4813 10 colic colic NN cord-022526-j9kg00qf 4813 11 are be VBP cord-022526-j9kg00qf 4813 12 the the DT cord-022526-j9kg00qf 4813 13 packed packed JJ cord-022526-j9kg00qf 4813 14 cell cell NN cord-022526-j9kg00qf 4813 15 volume volume NN cord-022526-j9kg00qf 4813 16 and and CC cord-022526-j9kg00qf 4813 17 total total JJ cord-022526-j9kg00qf 4813 18 protein protein NN cord-022526-j9kg00qf 4813 19 , , , cord-022526-j9kg00qf 4813 20 because because IN cord-022526-j9kg00qf 4813 21 one one PRP cord-022526-j9kg00qf 4813 22 can can MD cord-022526-j9kg00qf 4813 23 use use VB cord-022526-j9kg00qf 4813 24 them -PRON- PRP cord-022526-j9kg00qf 4813 25 to to TO cord-022526-j9kg00qf 4813 26 substantiate substantiate VB cord-022526-j9kg00qf 4813 27 clinical clinical JJ cord-022526-j9kg00qf 4813 28 estimates estimate NNS cord-022526-j9kg00qf 4813 29 of of IN cord-022526-j9kg00qf 4813 30 dehydration dehydration NN cord-022526-j9kg00qf 4813 31 and and CC cord-022526-j9kg00qf 4813 32 they -PRON- PRP cord-022526-j9kg00qf 4813 33 correlate correlate VBP cord-022526-j9kg00qf 4813 34 strongly strongly RB cord-022526-j9kg00qf 4813 35 with with IN cord-022526-j9kg00qf 4813 36 prognosis prognosis NN cord-022526-j9kg00qf 4813 37 . . . cord-022526-j9kg00qf 4814 1 20 20 CD cord-022526-j9kg00qf 4814 2 , , , cord-022526-j9kg00qf 4814 3 21 21 CD cord-022526-j9kg00qf 4814 4 A a DT cord-022526-j9kg00qf 4814 5 serum serum NN cord-022526-j9kg00qf 4814 6 biochemical biochemical JJ cord-022526-j9kg00qf 4814 7 profile profile NN cord-022526-j9kg00qf 4814 8 is be VBZ cord-022526-j9kg00qf 4814 9 useful useful JJ cord-022526-j9kg00qf 4814 10 for for IN cord-022526-j9kg00qf 4814 11 assessing assess VBG cord-022526-j9kg00qf 4814 12 electrolyte electrolyte JJ cord-022526-j9kg00qf 4814 13 imbalances imbalance NNS cord-022526-j9kg00qf 4814 14 , , , cord-022526-j9kg00qf 4814 15 tissue tissue NN cord-022526-j9kg00qf 4814 16 perfusion perfusion NN cord-022526-j9kg00qf 4814 17 ( ( -LRB- cord-022526-j9kg00qf 4814 18 anion anion NN cord-022526-j9kg00qf 4814 19 gap gap NN cord-022526-j9kg00qf 4814 20 or or CC cord-022526-j9kg00qf 4814 21 lactate lactate NN cord-022526-j9kg00qf 4814 22 ) ) -RRB- cord-022526-j9kg00qf 4814 23 , , , cord-022526-j9kg00qf 4814 24 and and CC cord-022526-j9kg00qf 4814 25 kidney kidney NN cord-022526-j9kg00qf 4814 26 and and CC cord-022526-j9kg00qf 4814 27 liver liver NN cord-022526-j9kg00qf 4814 28 function function NN cord-022526-j9kg00qf 4814 29 . . . cord-022526-j9kg00qf 4815 1 One one PRP cord-022526-j9kg00qf 4815 2 can can MD cord-022526-j9kg00qf 4815 3 use use VB cord-022526-j9kg00qf 4815 4 serum serum NN cord-022526-j9kg00qf 4815 5 biochemical biochemical JJ cord-022526-j9kg00qf 4815 6 or or CC cord-022526-j9kg00qf 4815 7 blood blood NN cord-022526-j9kg00qf 4815 8 gas gas NN cord-022526-j9kg00qf 4815 9 analysis analysis NN cord-022526-j9kg00qf 4815 10 to to TO cord-022526-j9kg00qf 4815 11 assess assess VB cord-022526-j9kg00qf 4815 12 acid acid NN cord-022526-j9kg00qf 4815 13 - - HYPH cord-022526-j9kg00qf 4815 14 base base NN cord-022526-j9kg00qf 4815 15 status status NN cord-022526-j9kg00qf 4815 16 . . . cord-022526-j9kg00qf 4816 1 Horses horse NNS cord-022526-j9kg00qf 4816 2 with with IN cord-022526-j9kg00qf 4816 3 colic colic NN cord-022526-j9kg00qf 4816 4 most most RBS cord-022526-j9kg00qf 4816 5 frequently frequently RB cord-022526-j9kg00qf 4816 6 show show VBP cord-022526-j9kg00qf 4816 7 evidence evidence NN cord-022526-j9kg00qf 4816 8 of of IN cord-022526-j9kg00qf 4816 9 metabolic metabolic JJ cord-022526-j9kg00qf 4816 10 acidosis acidosis NN cord-022526-j9kg00qf 4816 11 associated associate VBN cord-022526-j9kg00qf 4816 12 with with IN cord-022526-j9kg00qf 4816 13 poor poor JJ cord-022526-j9kg00qf 4816 14 tissue tissue NN cord-022526-j9kg00qf 4816 15 perfusion perfusion NN cord-022526-j9kg00qf 4816 16 caused cause VBN cord-022526-j9kg00qf 4816 17 by by IN cord-022526-j9kg00qf 4816 18 hypovolemia hypovolemia NN cord-022526-j9kg00qf 4816 19 or or CC cord-022526-j9kg00qf 4816 20 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4816 21 , , , cord-022526-j9kg00qf 4816 22 but but CC cord-022526-j9kg00qf 4816 23 one one PRP cord-022526-j9kg00qf 4816 24 may may MD cord-022526-j9kg00qf 4816 25 note note VB cord-022526-j9kg00qf 4816 26 other other JJ cord-022526-j9kg00qf 4816 27 abnormalities abnormality NNS cord-022526-j9kg00qf 4816 28 such such JJ cord-022526-j9kg00qf 4816 29 as as IN cord-022526-j9kg00qf 4816 30 metabolic metabolic JJ cord-022526-j9kg00qf 4816 31 alkalosis alkalosis NN cord-022526-j9kg00qf 4816 32 in in IN cord-022526-j9kg00qf 4816 33 association association NN cord-022526-j9kg00qf 4816 34 with with IN cord-022526-j9kg00qf 4816 35 extensive extensive JJ cord-022526-j9kg00qf 4816 36 loss loss NN cord-022526-j9kg00qf 4816 37 or or CC cord-022526-j9kg00qf 4816 38 sequestration sequestration NN cord-022526-j9kg00qf 4816 39 of of IN cord-022526-j9kg00qf 4816 40 stomach stomach NN cord-022526-j9kg00qf 4816 41 chloride chloride NN cord-022526-j9kg00qf 4816 42 . . . cord-022526-j9kg00qf 4817 1 Metabolic metabolic JJ cord-022526-j9kg00qf 4817 2 acidosis acidosis NN cord-022526-j9kg00qf 4817 3 has have VBZ cord-022526-j9kg00qf 4817 4 been be VBN cord-022526-j9kg00qf 4817 5 investigated investigate VBN cord-022526-j9kg00qf 4817 6 further further RB cord-022526-j9kg00qf 4817 7 in in IN cord-022526-j9kg00qf 4817 8 horses horse NNS cord-022526-j9kg00qf 4817 9 with with IN cord-022526-j9kg00qf 4817 10 colic colic NN cord-022526-j9kg00qf 4817 11 by by IN cord-022526-j9kg00qf 4817 12 measuring measure VBG cord-022526-j9kg00qf 4817 13 blood blood NN cord-022526-j9kg00qf 4817 14 lactate lactate NN cord-022526-j9kg00qf 4817 15 , , , cord-022526-j9kg00qf 4817 16 although although IN cord-022526-j9kg00qf 4817 17 this this DT cord-022526-j9kg00qf 4817 18 test test NN cord-022526-j9kg00qf 4817 19 is be VBZ cord-022526-j9kg00qf 4817 20 not not RB cord-022526-j9kg00qf 4817 21 offered offer VBN cord-022526-j9kg00qf 4817 22 routinely routinely RB cord-022526-j9kg00qf 4817 23 in in IN cord-022526-j9kg00qf 4817 24 many many JJ cord-022526-j9kg00qf 4817 25 laboratories laboratory NNS cord-022526-j9kg00qf 4817 26 . . . cord-022526-j9kg00qf 4818 1 Lactate lactate NN cord-022526-j9kg00qf 4818 2 levels level NNS cord-022526-j9kg00qf 4818 3 also also RB cord-022526-j9kg00qf 4818 4 have have VBP cord-022526-j9kg00qf 4818 5 been be VBN cord-022526-j9kg00qf 4818 6 inferred infer VBN cord-022526-j9kg00qf 4818 7 from from IN cord-022526-j9kg00qf 4818 8 measurement measurement NN cord-022526-j9kg00qf 4818 9 of of IN cord-022526-j9kg00qf 4818 10 the the DT cord-022526-j9kg00qf 4818 11 anion anion NN cord-022526-j9kg00qf 4818 12 gap gap NN cord-022526-j9kg00qf 4818 13 , , , cord-022526-j9kg00qf 4818 14 although although IN cord-022526-j9kg00qf 4818 15 one one CD cord-022526-j9kg00qf 4818 16 study study NN cord-022526-j9kg00qf 4818 17 noted note VBD cord-022526-j9kg00qf 4818 18 that that IN cord-022526-j9kg00qf 4818 19 lactate lactate NN cord-022526-j9kg00qf 4818 20 in in IN cord-022526-j9kg00qf 4818 21 horses horse NNS cord-022526-j9kg00qf 4818 22 with with IN cord-022526-j9kg00qf 4818 23 colic colic NN cord-022526-j9kg00qf 4818 24 did do VBD cord-022526-j9kg00qf 4818 25 not not RB cord-022526-j9kg00qf 4818 26 account account VB cord-022526-j9kg00qf 4818 27 for for IN cord-022526-j9kg00qf 4818 28 the the DT cord-022526-j9kg00qf 4818 29 entire entire JJ cord-022526-j9kg00qf 4818 30 anion anion NN cord-022526-j9kg00qf 4818 31 gap gap NN cord-022526-j9kg00qf 4818 32 . . . cord-022526-j9kg00qf 4819 1 22 22 CD cord-022526-j9kg00qf 4819 2 Lactate Lactate NNP cord-022526-j9kg00qf 4819 3 levels level NNS cord-022526-j9kg00qf 4819 4 and and CC cord-022526-j9kg00qf 4819 5 anion anion NN cord-022526-j9kg00qf 4819 6 gap gap NN cord-022526-j9kg00qf 4819 7 closely closely RB cord-022526-j9kg00qf 4819 8 correlate correlate VBP cord-022526-j9kg00qf 4819 9 with with IN cord-022526-j9kg00qf 4819 10 prognosis prognosis NN cord-022526-j9kg00qf 4819 11 for for IN cord-022526-j9kg00qf 4819 12 survival survival NN cord-022526-j9kg00qf 4819 13 . . . cord-022526-j9kg00qf 4820 1 20 20 CD cord-022526-j9kg00qf 4820 2 , , , cord-022526-j9kg00qf 4820 3 23 23 CD cord-022526-j9kg00qf 4820 4 , , , cord-022526-j9kg00qf 4820 5 24 24 CD cord-022526-j9kg00qf 4820 6 Other other JJ cord-022526-j9kg00qf 4820 7 key key JJ cord-022526-j9kg00qf 4820 8 components component NNS cord-022526-j9kg00qf 4820 9 of of IN cord-022526-j9kg00qf 4820 10 assessment assessment NN cord-022526-j9kg00qf 4820 11 of of IN cord-022526-j9kg00qf 4820 12 the the DT cord-022526-j9kg00qf 4820 13 horse horse NN cord-022526-j9kg00qf 4820 14 with with IN cord-022526-j9kg00qf 4820 15 colic colic NN cord-022526-j9kg00qf 4820 16 are be VBP cord-022526-j9kg00qf 4820 17 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4820 18 and and CC cord-022526-j9kg00qf 4820 19 complete complete JJ cord-022526-j9kg00qf 4820 20 blood blood NN cord-022526-j9kg00qf 4820 21 count count NN cord-022526-j9kg00qf 4820 22 . . . cord-022526-j9kg00qf 4821 1 The the DT cord-022526-j9kg00qf 4821 2 total total JJ cord-022526-j9kg00qf 4821 3 white white JJ cord-022526-j9kg00qf 4821 4 blood blood NN cord-022526-j9kg00qf 4821 5 cell cell NN cord-022526-j9kg00qf 4821 6 count count NN cord-022526-j9kg00qf 4821 7 and and CC cord-022526-j9kg00qf 4821 8 differential differential NN cord-022526-j9kg00qf 4821 9 can can MD cord-022526-j9kg00qf 4821 10 provide provide VB cord-022526-j9kg00qf 4821 11 crucial crucial JJ cord-022526-j9kg00qf 4821 12 evidence evidence NN cord-022526-j9kg00qf 4821 13 of of IN cord-022526-j9kg00qf 4821 14 systemic systemic JJ cord-022526-j9kg00qf 4821 15 inflammation inflammation NN cord-022526-j9kg00qf 4821 16 associated associate VBN cord-022526-j9kg00qf 4821 17 with with IN cord-022526-j9kg00qf 4821 18 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4821 19 stemming stem VBG cord-022526-j9kg00qf 4821 20 from from IN cord-022526-j9kg00qf 4821 21 colic colic NN cord-022526-j9kg00qf 4821 22 attributable attributable JJ cord-022526-j9kg00qf 4821 23 to to IN cord-022526-j9kg00qf 4821 24 colitis colitis NN cord-022526-j9kg00qf 4821 25 ( ( -LRB- cord-022526-j9kg00qf 4821 26 leukopenia leukopenia NN cord-022526-j9kg00qf 4821 27 , , , cord-022526-j9kg00qf 4821 28 neutropenia neutropenia NN cord-022526-j9kg00qf 4821 29 , , , cord-022526-j9kg00qf 4821 30 and and CC cord-022526-j9kg00qf 4821 31 a a DT cord-022526-j9kg00qf 4821 32 left left JJ cord-022526-j9kg00qf 4821 33 shift shift NN cord-022526-j9kg00qf 4821 34 ) ) -RRB- cord-022526-j9kg00qf 4821 35 rather rather RB cord-022526-j9kg00qf 4821 36 than than IN cord-022526-j9kg00qf 4821 37 an an DT cord-022526-j9kg00qf 4821 38 obstruction obstruction NN cord-022526-j9kg00qf 4821 39 ( ( -LRB- cord-022526-j9kg00qf 4821 40 highly highly RB cord-022526-j9kg00qf 4821 41 variable variable JJ cord-022526-j9kg00qf 4821 42 complete complete JJ cord-022526-j9kg00qf 4821 43 blood blood NN cord-022526-j9kg00qf 4821 44 count count NN cord-022526-j9kg00qf 4821 45 findings finding NNS cord-022526-j9kg00qf 4821 46 ) ) -RRB- cord-022526-j9kg00qf 4821 47 . . . cord-022526-j9kg00qf 4822 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 4822 2 fluid fluid NN cord-022526-j9kg00qf 4822 3 may may MD cord-022526-j9kg00qf 4822 4 be be VB cord-022526-j9kg00qf 4822 5 helpful helpful JJ cord-022526-j9kg00qf 4822 6 in in IN cord-022526-j9kg00qf 4822 7 determining determine VBG cord-022526-j9kg00qf 4822 8 the the DT cord-022526-j9kg00qf 4822 9 integrity integrity NN cord-022526-j9kg00qf 4822 10 of of IN cord-022526-j9kg00qf 4822 11 the the DT cord-022526-j9kg00qf 4822 12 intestine intestine NN cord-022526-j9kg00qf 4822 13 . . . cord-022526-j9kg00qf 4823 1 Specifically specifically RB cord-022526-j9kg00qf 4823 2 , , , cord-022526-j9kg00qf 4823 3 as as IN cord-022526-j9kg00qf 4823 4 the the DT cord-022526-j9kg00qf 4823 5 intestine intestine NN cord-022526-j9kg00qf 4823 6 becomes become VBZ cord-022526-j9kg00qf 4823 7 progressively progressively RB cord-022526-j9kg00qf 4823 8 devitalized devitalize VBN cord-022526-j9kg00qf 4823 9 , , , cord-022526-j9kg00qf 4823 10 the the DT cord-022526-j9kg00qf 4823 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 4823 12 fluid fluid NN cord-022526-j9kg00qf 4823 13 becomes become VBZ cord-022526-j9kg00qf 4823 14 serosanguinous serosanguinous JJ cord-022526-j9kg00qf 4823 15 as as IN cord-022526-j9kg00qf 4823 16 red red JJ cord-022526-j9kg00qf 4823 17 blood blood NN cord-022526-j9kg00qf 4823 18 cells cell NNS cord-022526-j9kg00qf 4823 19 leak leak VBP cord-022526-j9kg00qf 4823 20 into into IN cord-022526-j9kg00qf 4823 21 the the DT cord-022526-j9kg00qf 4823 22 abdomen abdomen NN cord-022526-j9kg00qf 4823 23 , , , cord-022526-j9kg00qf 4823 24 followed follow VBN cord-022526-j9kg00qf 4823 25 by by IN cord-022526-j9kg00qf 4823 26 an an DT cord-022526-j9kg00qf 4823 27 elevation elevation NN cord-022526-j9kg00qf 4823 28 in in IN cord-022526-j9kg00qf 4823 29 the the DT cord-022526-j9kg00qf 4823 30 total total JJ cord-022526-j9kg00qf 4823 31 protein protein NN cord-022526-j9kg00qf 4823 32 ( ( -LRB- cord-022526-j9kg00qf 4823 33 > > NFP cord-022526-j9kg00qf 4823 34 2.5 2.5 CD cord-022526-j9kg00qf 4823 35 g g NN cord-022526-j9kg00qf 4823 36 / / SYM cord-022526-j9kg00qf 4823 37 dl dl NN cord-022526-j9kg00qf 4823 38 ) ) -RRB- cord-022526-j9kg00qf 4823 39 and and CC cord-022526-j9kg00qf 4823 40 progressive progressive JJ cord-022526-j9kg00qf 4823 41 increases increase NNS cord-022526-j9kg00qf 4823 42 in in IN cord-022526-j9kg00qf 4823 43 total total JJ cord-022526-j9kg00qf 4823 44 nucleated nucleated JJ cord-022526-j9kg00qf 4823 45 cell cell NN cord-022526-j9kg00qf 4823 46 count count NN cord-022526-j9kg00qf 4823 47 ( ( -LRB- cord-022526-j9kg00qf 4823 48 > > VBZ cord-022526-j9kg00qf 4823 49 10,000 10,000 CD cord-022526-j9kg00qf 4823 50 cells/µl cells/µl NNP cord-022526-j9kg00qf 4823 51 ) ) -RRB- cord-022526-j9kg00qf 4823 52 . . . cord-022526-j9kg00qf 4824 1 However however RB cord-022526-j9kg00qf 4824 2 , , , cord-022526-j9kg00qf 4824 3 these these DT cord-022526-j9kg00qf 4824 4 findings finding NNS cord-022526-j9kg00qf 4824 5 do do VBP cord-022526-j9kg00qf 4824 6 not not RB cord-022526-j9kg00qf 4824 7 always always RB cord-022526-j9kg00qf 4824 8 correlate correlate VB cord-022526-j9kg00qf 4824 9 well well JJ cord-022526-j9kg00qf 4824 10 with with IN cord-022526-j9kg00qf 4824 11 the the DT cord-022526-j9kg00qf 4824 12 condition condition NN cord-022526-j9kg00qf 4824 13 of of IN cord-022526-j9kg00qf 4824 14 the the DT cord-022526-j9kg00qf 4824 15 intestine intestine NN cord-022526-j9kg00qf 4824 16 , , , cord-022526-j9kg00qf 4824 17 particularly particularly RB cord-022526-j9kg00qf 4824 18 in in IN cord-022526-j9kg00qf 4824 19 horses horse NNS cord-022526-j9kg00qf 4824 20 with with IN cord-022526-j9kg00qf 4824 21 large large JJ cord-022526-j9kg00qf 4824 22 colon colon NN cord-022526-j9kg00qf 4824 23 volvulus volvulus NN cord-022526-j9kg00qf 4824 24 . . . cord-022526-j9kg00qf 4825 1 For for IN cord-022526-j9kg00qf 4825 2 example example NN cord-022526-j9kg00qf 4825 3 , , , cord-022526-j9kg00qf 4825 4 in in IN cord-022526-j9kg00qf 4825 5 a a DT cord-022526-j9kg00qf 4825 6 study study NN cord-022526-j9kg00qf 4825 7 of of IN cord-022526-j9kg00qf 4825 8 57 57 CD cord-022526-j9kg00qf 4825 9 horses horse NNS cord-022526-j9kg00qf 4825 10 with with IN cord-022526-j9kg00qf 4825 11 large large JJ cord-022526-j9kg00qf 4825 12 colon colon NN cord-022526-j9kg00qf 4825 13 volvulus volvulus NN cord-022526-j9kg00qf 4825 14 , , , cord-022526-j9kg00qf 4825 15 the the DT cord-022526-j9kg00qf 4825 16 average average JJ cord-022526-j9kg00qf 4825 17 total total JJ cord-022526-j9kg00qf 4825 18 protein protein NN cord-022526-j9kg00qf 4825 19 ( ( -LRB- cord-022526-j9kg00qf 4825 20 2.5 2.5 CD cord-022526-j9kg00qf 4825 21 g g NN cord-022526-j9kg00qf 4825 22 / / SYM cord-022526-j9kg00qf 4825 23 dl dl NN cord-022526-j9kg00qf 4825 24 ) ) -RRB- cord-022526-j9kg00qf 4825 25 and and CC cord-022526-j9kg00qf 4825 26 total total JJ cord-022526-j9kg00qf 4825 27 nucleated nucleated JJ cord-022526-j9kg00qf 4825 28 cell cell NN cord-022526-j9kg00qf 4825 29 count count NN cord-022526-j9kg00qf 4825 30 ( ( -LRB- cord-022526-j9kg00qf 4825 31 1000 1000 CD cord-022526-j9kg00qf 4825 32 cells/µl cells/µl NNP cord-022526-j9kg00qf 4825 33 ) ) -RRB- cord-022526-j9kg00qf 4825 34 were be VBD cord-022526-j9kg00qf 4825 35 normal normal JJ cord-022526-j9kg00qf 4825 36 despite despite IN cord-022526-j9kg00qf 4825 37 the the DT cord-022526-j9kg00qf 4825 38 fact fact NN cord-022526-j9kg00qf 4825 39 that that IN cord-022526-j9kg00qf 4825 40 only only RB cord-022526-j9kg00qf 4825 41 36 36 CD cord-022526-j9kg00qf 4825 42 % % NN cord-022526-j9kg00qf 4825 43 with with IN cord-022526-j9kg00qf 4825 44 a a DT cord-022526-j9kg00qf 4825 45 360-degree 360-degree CD cord-022526-j9kg00qf 4825 46 volvulus volvulus NN cord-022526-j9kg00qf 4825 47 survived survive VBN cord-022526-j9kg00qf 4825 48 . . . cord-022526-j9kg00qf 4826 1 4 4 CD cord-022526-j9kg00qf 4826 2 , , , cord-022526-j9kg00qf 4826 3 25 25 CD cord-022526-j9kg00qf 4827 1 These these DT cord-022526-j9kg00qf 4827 2 measures measure NNS cord-022526-j9kg00qf 4827 3 may may MD cord-022526-j9kg00qf 4827 4 appear appear VB cord-022526-j9kg00qf 4827 5 normal normal JJ cord-022526-j9kg00qf 4827 6 because because IN cord-022526-j9kg00qf 4827 7 the the DT cord-022526-j9kg00qf 4827 8 development development NN cord-022526-j9kg00qf 4827 9 of of IN cord-022526-j9kg00qf 4827 10 severe severe JJ cord-022526-j9kg00qf 4827 11 mucosal mucosal JJ cord-022526-j9kg00qf 4827 12 injury injury NN cord-022526-j9kg00qf 4827 13 following follow VBG cord-022526-j9kg00qf 4827 14 large large JJ cord-022526-j9kg00qf 4827 15 colon colon NN cord-022526-j9kg00qf 4827 16 volvulus volvulus NN cord-022526-j9kg00qf 4827 17 is be VBZ cord-022526-j9kg00qf 4827 18 rapid rapid JJ cord-022526-j9kg00qf 4827 19 and and CC cord-022526-j9kg00qf 4827 20 may may MD cord-022526-j9kg00qf 4827 21 not not RB cord-022526-j9kg00qf 4827 22 allow allow VB cord-022526-j9kg00qf 4827 23 enough enough JJ cord-022526-j9kg00qf 4827 24 time time NN cord-022526-j9kg00qf 4827 25 for for IN cord-022526-j9kg00qf 4827 26 protein protein NN cord-022526-j9kg00qf 4827 27 and and CC cord-022526-j9kg00qf 4827 28 leukocytes leukocyte NNS cord-022526-j9kg00qf 4827 29 to to TO cord-022526-j9kg00qf 4827 30 equilibrate equilibrate VB cord-022526-j9kg00qf 4827 31 with with IN cord-022526-j9kg00qf 4827 32 the the DT cord-022526-j9kg00qf 4827 33 abdominal abdominal JJ cord-022526-j9kg00qf 4827 34 fluid fluid NN cord-022526-j9kg00qf 4827 35 . . . cord-022526-j9kg00qf 4828 1 26 26 CD cord-022526-j9kg00qf 4828 2 Investigators investigator NNS cord-022526-j9kg00qf 4828 3 have have VBP cord-022526-j9kg00qf 4828 4 taken take VBN cord-022526-j9kg00qf 4828 5 all all PDT cord-022526-j9kg00qf 4828 6 the the DT cord-022526-j9kg00qf 4828 7 variables variable NNS cord-022526-j9kg00qf 4828 8 routinely routinely RB cord-022526-j9kg00qf 4828 9 assessed assess VBN cord-022526-j9kg00qf 4828 10 during during IN cord-022526-j9kg00qf 4828 11 evaluation evaluation NN cord-022526-j9kg00qf 4828 12 of of IN cord-022526-j9kg00qf 4828 13 horses horse NNS cord-022526-j9kg00qf 4828 14 for for IN cord-022526-j9kg00qf 4828 15 colic colic NN cord-022526-j9kg00qf 4828 16 and and CC cord-022526-j9kg00qf 4828 17 have have VBP cord-022526-j9kg00qf 4828 18 attempted attempt VBN cord-022526-j9kg00qf 4828 19 to to TO cord-022526-j9kg00qf 4828 20 develop develop VB cord-022526-j9kg00qf 4828 21 models model NNS cord-022526-j9kg00qf 4828 22 to to TO cord-022526-j9kg00qf 4828 23 predict predict VB cord-022526-j9kg00qf 4828 24 accurately accurately RB cord-022526-j9kg00qf 4828 25 the the DT cord-022526-j9kg00qf 4828 26 need need NN cord-022526-j9kg00qf 4828 27 for for IN cord-022526-j9kg00qf 4828 28 surgery surgery NN cord-022526-j9kg00qf 4828 29 and and CC cord-022526-j9kg00qf 4828 30 the the DT cord-022526-j9kg00qf 4828 31 prognosis prognosis NN cord-022526-j9kg00qf 4828 32 for for IN cord-022526-j9kg00qf 4828 33 life life NN cord-022526-j9kg00qf 4828 34 . . . cord-022526-j9kg00qf 4829 1 [ [ -LRB- cord-022526-j9kg00qf 4829 2 27 27 CD cord-022526-j9kg00qf 4829 3 ] ] -RRB- cord-022526-j9kg00qf 4829 4 [ [ -LRB- cord-022526-j9kg00qf 4829 5 28 28 CD cord-022526-j9kg00qf 4829 6 ] ] -RRB- cord-022526-j9kg00qf 4830 1 [ [ -LRB- cord-022526-j9kg00qf 4830 2 29 29 CD cord-022526-j9kg00qf 4830 3 ] ] -RRB- cord-022526-j9kg00qf 4831 1 [ [ -LRB- cord-022526-j9kg00qf 4831 2 30 30 CD cord-022526-j9kg00qf 4831 3 ] ] -RRB- cord-022526-j9kg00qf 4832 1 None none NN cord-022526-j9kg00qf 4832 2 of of IN cord-022526-j9kg00qf 4832 3 these these DT cord-022526-j9kg00qf 4832 4 predictor predictor NN cord-022526-j9kg00qf 4832 5 models model NNS cord-022526-j9kg00qf 4832 6 has have VBZ cord-022526-j9kg00qf 4832 7 taken take VBN cord-022526-j9kg00qf 4832 8 the the DT cord-022526-j9kg00qf 4832 9 place place NN cord-022526-j9kg00qf 4832 10 of of IN cord-022526-j9kg00qf 4832 11 clinical clinical JJ cord-022526-j9kg00qf 4832 12 decision decision NN cord-022526-j9kg00qf 4832 13 making making NN cord-022526-j9kg00qf 4832 14 , , , cord-022526-j9kg00qf 4832 15 although although IN cord-022526-j9kg00qf 4832 16 these these DT cord-022526-j9kg00qf 4832 17 studies study NNS cord-022526-j9kg00qf 4832 18 have have VBP cord-022526-j9kg00qf 4832 19 added add VBN cord-022526-j9kg00qf 4832 20 924 924 CD cord-022526-j9kg00qf 4832 21 PART part NN cord-022526-j9kg00qf 4832 22 II ii CD cord-022526-j9kg00qf 4832 23 Disorders disorder NNS cord-022526-j9kg00qf 4832 24 of of IN cord-022526-j9kg00qf 4832 25 Specific specific JJ cord-022526-j9kg00qf 4832 26 Body Body NNP cord-022526-j9kg00qf 4832 27 Systems Systems NNPS cord-022526-j9kg00qf 4832 28 signs sign NNS cord-022526-j9kg00qf 4832 29 are be VBP cord-022526-j9kg00qf 4832 30 excellent excellent JJ cord-022526-j9kg00qf 4832 31 predictors predictor NNS cord-022526-j9kg00qf 4832 32 of of IN cord-022526-j9kg00qf 4832 33 whether whether IN cord-022526-j9kg00qf 4832 34 a a DT cord-022526-j9kg00qf 4832 35 horse horse NN cord-022526-j9kg00qf 4832 36 requires require VBZ cord-022526-j9kg00qf 4832 37 surgical surgical JJ cord-022526-j9kg00qf 4832 38 exploration exploration NN cord-022526-j9kg00qf 4832 39 of of IN cord-022526-j9kg00qf 4832 40 the the DT cord-022526-j9kg00qf 4832 41 abdomen abdomen NN cord-022526-j9kg00qf 4832 42 . . . cord-022526-j9kg00qf 4833 1 In in IN cord-022526-j9kg00qf 4833 2 fact fact NN cord-022526-j9kg00qf 4833 3 , , , cord-022526-j9kg00qf 4833 4 refractory refractory JJ cord-022526-j9kg00qf 4833 5 pain pain NN cord-022526-j9kg00qf 4833 6 supersedes supersede VBZ cord-022526-j9kg00qf 4833 7 all all DT cord-022526-j9kg00qf 4833 8 other other JJ cord-022526-j9kg00qf 4833 9 predictors predictor NNS cord-022526-j9kg00qf 4833 10 of of IN cord-022526-j9kg00qf 4833 11 the the DT cord-022526-j9kg00qf 4833 12 need need NN cord-022526-j9kg00qf 4833 13 for for IN cord-022526-j9kg00qf 4833 14 surgery surgery NN cord-022526-j9kg00qf 4833 15 in in IN cord-022526-j9kg00qf 4833 16 the the DT cord-022526-j9kg00qf 4833 17 colic colic NN cord-022526-j9kg00qf 4833 18 patient patient NN cord-022526-j9kg00qf 4833 19 . . . cord-022526-j9kg00qf 4834 1 Once once IN cord-022526-j9kg00qf 4834 2 signs sign NNS cord-022526-j9kg00qf 4834 3 of of IN cord-022526-j9kg00qf 4834 4 colic colic NN cord-022526-j9kg00qf 4834 5 have have VBP cord-022526-j9kg00qf 4834 6 been be VBN cord-022526-j9kg00qf 4834 7 recognized recognize VBN cord-022526-j9kg00qf 4834 8 and and CC cord-022526-j9kg00qf 4834 9 categorized categorize VBN cord-022526-j9kg00qf 4834 10 as as IN cord-022526-j9kg00qf 4834 11 to to IN cord-022526-j9kg00qf 4834 12 their -PRON- PRP$ cord-022526-j9kg00qf 4834 13 severity severity NN cord-022526-j9kg00qf 4834 14 , , , cord-022526-j9kg00qf 4834 15 rapidly rapidly RB cord-022526-j9kg00qf 4834 16 and and CC cord-022526-j9kg00qf 4834 17 effectively effectively RB cord-022526-j9kg00qf 4834 18 relieving relieve VBG cord-022526-j9kg00qf 4834 19 the the DT cord-022526-j9kg00qf 4834 20 pain pain NN cord-022526-j9kg00qf 4834 21 is be VBZ cord-022526-j9kg00qf 4834 22 critical critical JJ cord-022526-j9kg00qf 4834 23 for for IN cord-022526-j9kg00qf 4834 24 the the DT cord-022526-j9kg00qf 4834 25 well well NN cord-022526-j9kg00qf 4834 26 - - HYPH cord-022526-j9kg00qf 4834 27 being being NN cord-022526-j9kg00qf 4834 28 of of IN cord-022526-j9kg00qf 4834 29 the the DT cord-022526-j9kg00qf 4834 30 horse horse NN cord-022526-j9kg00qf 4834 31 and and CC cord-022526-j9kg00qf 4834 32 to to TO cord-022526-j9kg00qf 4834 33 reduce reduce VB cord-022526-j9kg00qf 4834 34 the the DT cord-022526-j9kg00qf 4834 35 owner owner NN cord-022526-j9kg00qf 4834 36 's 's POS cord-022526-j9kg00qf 4834 37 anxiety anxiety NN cord-022526-j9kg00qf 4834 38 . . . cord-022526-j9kg00qf 4835 1 In in IN cord-022526-j9kg00qf 4835 2 addition addition NN cord-022526-j9kg00qf 4835 3 , , , cord-022526-j9kg00qf 4835 4 pain pain NN cord-022526-j9kg00qf 4835 5 is be VBZ cord-022526-j9kg00qf 4835 6 best well RBS cord-022526-j9kg00qf 4835 7 managed manage VBN cord-022526-j9kg00qf 4835 8 before before IN cord-022526-j9kg00qf 4835 9 it -PRON- PRP cord-022526-j9kg00qf 4835 10 becomes become VBZ cord-022526-j9kg00qf 4835 11 severe severe JJ cord-022526-j9kg00qf 4835 12 . . . cord-022526-j9kg00qf 4836 1 13 13 CD cord-022526-j9kg00qf 4837 1 Several several JJ cord-022526-j9kg00qf 4837 2 classes class NNS cord-022526-j9kg00qf 4837 3 of of IN cord-022526-j9kg00qf 4837 4 analgesics analgesic NNS cord-022526-j9kg00qf 4837 5 are be VBP cord-022526-j9kg00qf 4837 6 readily readily RB cord-022526-j9kg00qf 4837 7 available available JJ cord-022526-j9kg00qf 4837 8 to to TO cord-022526-j9kg00qf 4837 9 treat treat VB cord-022526-j9kg00qf 4837 10 horses horse NNS cord-022526-j9kg00qf 4837 11 with with IN cord-022526-j9kg00qf 4837 12 colic colic NN cord-022526-j9kg00qf 4837 13 ( ( -LRB- cord-022526-j9kg00qf 4837 14 Table Table NNP cord-022526-j9kg00qf 4837 15 13 13 CD cord-022526-j9kg00qf 4837 16 . . . cord-022526-j9kg00qf 4838 1 15 15 CD cord-022526-j9kg00qf 4838 2 - - SYM cord-022526-j9kg00qf 4838 3 3 3 CD cord-022526-j9kg00qf 4838 4 ) ) -RRB- cord-022526-j9kg00qf 4838 5 , , , cord-022526-j9kg00qf 4838 6 including include VBG cord-022526-j9kg00qf 4838 7 α α NN cord-022526-j9kg00qf 4838 8 2 2 CD cord-022526-j9kg00qf 4838 9 -agonists -agonist NNS cord-022526-j9kg00qf 4838 10 ( ( -LRB- cord-022526-j9kg00qf 4838 11 xylazine xylazine NNP cord-022526-j9kg00qf 4838 12 , , , cord-022526-j9kg00qf 4838 13 detomidine detomidine NNP cord-022526-j9kg00qf 4838 14 ) ) -RRB- cord-022526-j9kg00qf 4838 15 , , , cord-022526-j9kg00qf 4838 16 opiates opiate NNS cord-022526-j9kg00qf 4838 17 ( ( -LRB- cord-022526-j9kg00qf 4838 18 butorphanol butorphanol NNP cord-022526-j9kg00qf 4838 19 ) ) -RRB- cord-022526-j9kg00qf 4838 20 , , , cord-022526-j9kg00qf 4838 21 and and CC cord-022526-j9kg00qf 4838 22 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 4838 23 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 4838 24 drugs drug NNS cord-022526-j9kg00qf 4838 25 ( ( -LRB- cord-022526-j9kg00qf 4838 26 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 4838 27 , , , cord-022526-j9kg00qf 4838 28 such such JJ cord-022526-j9kg00qf 4838 29 as as IN cord-022526-j9kg00qf 4838 30 flunixin flunixin NNP cord-022526-j9kg00qf 4838 31 meglumine meglumine NNP cord-022526-j9kg00qf 4838 32 ) ) -RRB- cord-022526-j9kg00qf 4838 33 . . . cord-022526-j9kg00qf 4839 1 Although although IN cord-022526-j9kg00qf 4839 2 much much JJ cord-022526-j9kg00qf 4839 3 of of IN cord-022526-j9kg00qf 4839 4 this this DT cord-022526-j9kg00qf 4839 5 information information NN cord-022526-j9kg00qf 4839 6 is be VBZ cord-022526-j9kg00qf 4839 7 familiar familiar JJ cord-022526-j9kg00qf 4839 8 to to IN cord-022526-j9kg00qf 4839 9 most most JJS cord-022526-j9kg00qf 4839 10 practitioners practitioner NNS cord-022526-j9kg00qf 4839 11 , , , cord-022526-j9kg00qf 4839 12 several several JJ cord-022526-j9kg00qf 4839 13 principles principle NNS cord-022526-j9kg00qf 4839 14 deserve deserve VBP cord-022526-j9kg00qf 4839 15 emphasis emphasis NN cord-022526-j9kg00qf 4839 16 . . . cord-022526-j9kg00qf 4840 1 The the DT cord-022526-j9kg00qf 4840 2 short short JJ cord-022526-j9kg00qf 4840 3 - - HYPH cord-022526-j9kg00qf 4840 4 duration duration NN cord-022526-j9kg00qf 4840 5 drugs drug NNS cord-022526-j9kg00qf 4840 6 xylazine xylazine NN cord-022526-j9kg00qf 4840 7 and and CC cord-022526-j9kg00qf 4840 8 butorphanol butorphanol NNP cord-022526-j9kg00qf 4840 9 , , , cord-022526-j9kg00qf 4840 10 which which WDT cord-022526-j9kg00qf 4840 11 provide provide VBP cord-022526-j9kg00qf 4840 12 analgesia analgesia NN cord-022526-j9kg00qf 4840 13 for for IN cord-022526-j9kg00qf 4840 14 30 30 CD cord-022526-j9kg00qf 4840 15 to to TO cord-022526-j9kg00qf 4840 16 45 45 CD cord-022526-j9kg00qf 4840 17 minutes minute NNS cord-022526-j9kg00qf 4840 18 , , , cord-022526-j9kg00qf 4840 19 allow allow VB cord-022526-j9kg00qf 4840 20 the the DT cord-022526-j9kg00qf 4840 21 veterinarian veterinarian NN cord-022526-j9kg00qf 4840 22 to to TO cord-022526-j9kg00qf 4840 23 determine determine VB cord-022526-j9kg00qf 4840 24 if if IN cord-022526-j9kg00qf 4840 25 pain pain NN cord-022526-j9kg00qf 4840 26 is be VBZ cord-022526-j9kg00qf 4840 27 recurrent recurrent JJ cord-022526-j9kg00qf 4840 28 within within IN cord-022526-j9kg00qf 4840 29 the the DT cord-022526-j9kg00qf 4840 30 time time NN cord-022526-j9kg00qf 4840 31 period period NN cord-022526-j9kg00qf 4840 32 of of IN cord-022526-j9kg00qf 4840 33 the the DT cord-022526-j9kg00qf 4840 34 typical typical JJ cord-022526-j9kg00qf 4840 35 examination examination NN cord-022526-j9kg00qf 4840 36 . . . cord-022526-j9kg00qf 4841 1 In in IN cord-022526-j9kg00qf 4841 2 contrast contrast NN cord-022526-j9kg00qf 4841 3 , , , cord-022526-j9kg00qf 4841 4 flunixin flunixin NNP cord-022526-j9kg00qf 4841 5 meglumine meglumine NNP cord-022526-j9kg00qf 4841 6 is be VBZ cord-022526-j9kg00qf 4841 7 not not RB cord-022526-j9kg00qf 4841 8 as as RB cord-022526-j9kg00qf 4841 9 potent potent JJ cord-022526-j9kg00qf 4841 10 as as IN cord-022526-j9kg00qf 4841 11 an an DT cord-022526-j9kg00qf 4841 12 analgesic analgesic NN cord-022526-j9kg00qf 4841 13 but but CC cord-022526-j9kg00qf 4841 14 has have VBZ cord-022526-j9kg00qf 4841 15 a a DT cord-022526-j9kg00qf 4841 16 much much RB cord-022526-j9kg00qf 4841 17 longer long JJR cord-022526-j9kg00qf 4841 18 duration duration NN cord-022526-j9kg00qf 4841 19 of of IN cord-022526-j9kg00qf 4841 20 action action NN cord-022526-j9kg00qf 4841 21 . . . cord-022526-j9kg00qf 4842 1 To to TO cord-022526-j9kg00qf 4842 2 avoid avoid VB cord-022526-j9kg00qf 4842 3 deleterious deleterious JJ cord-022526-j9kg00qf 4842 4 effects effect NNS cord-022526-j9kg00qf 4842 5 on on IN cord-022526-j9kg00qf 4842 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4842 7 mucosa mucosa NN cord-022526-j9kg00qf 4842 8 and and CC cord-022526-j9kg00qf 4842 9 the the DT cord-022526-j9kg00qf 4842 10 kidneys kidney NNS cord-022526-j9kg00qf 4842 11 , , , cord-022526-j9kg00qf 4842 12 one one PRP cord-022526-j9kg00qf 4842 13 should should MD cord-022526-j9kg00qf 4842 14 not not RB cord-022526-j9kg00qf 4842 15 administer administer VB cord-022526-j9kg00qf 4842 16 flunixin flunixin NNP cord-022526-j9kg00qf 4842 17 meglumine meglumine NNP cord-022526-j9kg00qf 4842 18 more more RBR cord-022526-j9kg00qf 4842 19 frequently frequently RB cord-022526-j9kg00qf 4842 20 than than IN cord-022526-j9kg00qf 4842 21 recommended recommend VBN cord-022526-j9kg00qf 4842 22 . . . cord-022526-j9kg00qf 4843 1 14 14 CD cord-022526-j9kg00qf 4843 2 , , , cord-022526-j9kg00qf 4843 3 15 15 CD cord-022526-j9kg00qf 4844 1 The the DT cord-022526-j9kg00qf 4844 2 recent recent JJ cord-022526-j9kg00qf 4844 3 discovery discovery NN cord-022526-j9kg00qf 4844 4 of of IN cord-022526-j9kg00qf 4844 5 two two CD cord-022526-j9kg00qf 4844 6 isoforms isoform NNS cord-022526-j9kg00qf 4844 7 of of IN cord-022526-j9kg00qf 4844 8 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 4844 9 ( ( -LRB- cord-022526-j9kg00qf 4844 10 COX COX NNP cord-022526-j9kg00qf 4844 11 ) ) -RRB- cord-022526-j9kg00qf 4844 12 , , , cord-022526-j9kg00qf 4844 13 the the DT cord-022526-j9kg00qf 4844 14 enzyme enzyme NN cord-022526-j9kg00qf 4844 15 inhibited inhibit VBN cord-022526-j9kg00qf 4844 16 by by IN cord-022526-j9kg00qf 4844 17 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4844 18 , , , cord-022526-j9kg00qf 4844 19 has have VBZ cord-022526-j9kg00qf 4844 20 resulted result VBN cord-022526-j9kg00qf 4844 21 in in IN cord-022526-j9kg00qf 4844 22 discovery discovery NN cord-022526-j9kg00qf 4844 23 of of IN cord-022526-j9kg00qf 4844 24 drugs drug NNS cord-022526-j9kg00qf 4844 25 that that WDT cord-022526-j9kg00qf 4844 26 can can MD cord-022526-j9kg00qf 4844 27 more more RBR cord-022526-j9kg00qf 4844 28 selectively selectively RB cord-022526-j9kg00qf 4844 29 inhibit inhibit VB cord-022526-j9kg00qf 4844 30 proinflammatory proinflammatory JJ cord-022526-j9kg00qf 4844 31 COX-2 COX-2 NNP cord-022526-j9kg00qf 4844 32 while while IN cord-022526-j9kg00qf 4844 33 permitting permit VBG cord-022526-j9kg00qf 4844 34 continued continued JJ cord-022526-j9kg00qf 4844 35 constitutive constitutive JJ cord-022526-j9kg00qf 4844 36 production production NN cord-022526-j9kg00qf 4844 37 of of IN cord-022526-j9kg00qf 4844 38 prostanoids prostanoid NNS cord-022526-j9kg00qf 4844 39 . . . cord-022526-j9kg00qf 4845 1 Such such JJ cord-022526-j9kg00qf 4845 2 specificity specificity NN cord-022526-j9kg00qf 4845 3 may may MD cord-022526-j9kg00qf 4845 4 be be VB cord-022526-j9kg00qf 4845 5 advantageous advantageous JJ cord-022526-j9kg00qf 4845 6 in in IN cord-022526-j9kg00qf 4845 7 horses horse NNS cord-022526-j9kg00qf 4845 8 with with IN cord-022526-j9kg00qf 4845 9 colic colic NN cord-022526-j9kg00qf 4845 10 , , , cord-022526-j9kg00qf 4845 11 particularly particularly RB cord-022526-j9kg00qf 4845 12 when when WRB cord-022526-j9kg00qf 4845 13 one one PRP cord-022526-j9kg00qf 4845 14 considers consider VBZ cord-022526-j9kg00qf 4845 15 recent recent JJ cord-022526-j9kg00qf 4845 16 evidence evidence NN cord-022526-j9kg00qf 4845 17 of of IN cord-022526-j9kg00qf 4845 18 reduced reduce VBN cord-022526-j9kg00qf 4845 19 intestinal intestinal JJ cord-022526-j9kg00qf 4845 20 recovery recovery NN cord-022526-j9kg00qf 4845 21 from from IN cord-022526-j9kg00qf 4845 22 an an DT cord-022526-j9kg00qf 4845 23 ischemic ischemic JJ cord-022526-j9kg00qf 4845 24 event event NN cord-022526-j9kg00qf 4845 25 with with IN cord-022526-j9kg00qf 4845 26 flunixin flunixin NNP cord-022526-j9kg00qf 4845 27 compared compare VBN cord-022526-j9kg00qf 4845 28 with with IN cord-022526-j9kg00qf 4845 29 a a DT cord-022526-j9kg00qf 4845 30 drug drug NN cord-022526-j9kg00qf 4845 31 that that WDT cord-022526-j9kg00qf 4845 32 is be VBZ cord-022526-j9kg00qf 4845 33 more more RBR cord-022526-j9kg00qf 4845 34 selective selective JJ cord-022526-j9kg00qf 4845 35 for for IN cord-022526-j9kg00qf 4845 36 COX-2 COX-2 NNP cord-022526-j9kg00qf 4845 37 . . . cord-022526-j9kg00qf 4846 1 16 16 CD cord-022526-j9kg00qf 4847 1 One one PRP cord-022526-j9kg00qf 4847 2 should should MD cord-022526-j9kg00qf 4847 3 reserve reserve VB cord-022526-j9kg00qf 4847 4 the the DT cord-022526-j9kg00qf 4847 5 α α NN cord-022526-j9kg00qf 4847 6 2agonist 2agonist CD cord-022526-j9kg00qf 4847 7 detomidine detomidine NN cord-022526-j9kg00qf 4847 8 for for IN cord-022526-j9kg00qf 4847 9 horses horse NNS cord-022526-j9kg00qf 4847 10 with with IN cord-022526-j9kg00qf 4847 11 severe severe JJ cord-022526-j9kg00qf 4847 12 , , , cord-022526-j9kg00qf 4847 13 unrelenting unrelenting JJ cord-022526-j9kg00qf 4847 14 pain pain NN cord-022526-j9kg00qf 4847 15 because because IN cord-022526-j9kg00qf 4847 16 of of IN cord-022526-j9kg00qf 4847 17 its -PRON- PRP$ cord-022526-j9kg00qf 4847 18 tremendous tremendous JJ cord-022526-j9kg00qf 4847 19 potency potency NN cord-022526-j9kg00qf 4847 20 . . . cord-022526-j9kg00qf 4848 1 17 17 CD cord-022526-j9kg00qf 4849 1 In in IN cord-022526-j9kg00qf 4849 2 addition addition NN cord-022526-j9kg00qf 4849 3 , , , cord-022526-j9kg00qf 4849 4 one one PRP cord-022526-j9kg00qf 4849 5 should should MD cord-022526-j9kg00qf 4849 6 remember remember VB cord-022526-j9kg00qf 4849 7 that that IN cord-022526-j9kg00qf 4849 8 α α NN cord-022526-j9kg00qf 4849 9 2 2 CD cord-022526-j9kg00qf 4849 10 -agonists -agonist NNS cord-022526-j9kg00qf 4849 11 reduce reduce VB cord-022526-j9kg00qf 4849 12 the the DT cord-022526-j9kg00qf 4849 13 heart heart NN cord-022526-j9kg00qf 4849 14 rate rate NN cord-022526-j9kg00qf 4849 15 associated associate VBN cord-022526-j9kg00qf 4849 16 with with IN cord-022526-j9kg00qf 4849 17 a a DT cord-022526-j9kg00qf 4849 18 transient transient JJ cord-022526-j9kg00qf 4849 19 increase increase NN cord-022526-j9kg00qf 4849 20 in in IN cord-022526-j9kg00qf 4849 21 blood blood NN cord-022526-j9kg00qf 4849 22 pressure pressure NN cord-022526-j9kg00qf 4849 23 , , , cord-022526-j9kg00qf 4849 24 18 18 CD cord-022526-j9kg00qf 4849 25 , , , cord-022526-j9kg00qf 4849 26 19 19 CD cord-022526-j9kg00qf 4849 27 thereby thereby RB cord-022526-j9kg00qf 4849 28 reducing reduce VBG cord-022526-j9kg00qf 4849 29 the the DT cord-022526-j9kg00qf 4849 30 predictive predictive JJ cord-022526-j9kg00qf 4849 31 value value NN cord-022526-j9kg00qf 4849 32 of of IN cord-022526-j9kg00qf 4849 33 the the DT cord-022526-j9kg00qf 4849 34 heart heart NN cord-022526-j9kg00qf 4849 35 rate rate NN cord-022526-j9kg00qf 4849 36 and and CC cord-022526-j9kg00qf 4849 37 pulse pulse NN cord-022526-j9kg00qf 4849 38 pressure pressure NN cord-022526-j9kg00qf 4849 39 . . . cord-022526-j9kg00qf 4850 1 tremendously tremendously RB cord-022526-j9kg00qf 4850 2 to to IN cord-022526-j9kg00qf 4850 3 understanding understanding NN cord-022526-j9kg00qf 4850 4 of of IN cord-022526-j9kg00qf 4850 5 the the DT cord-022526-j9kg00qf 4850 6 importance importance NN cord-022526-j9kg00qf 4850 7 of of IN cord-022526-j9kg00qf 4850 8 some some DT cord-022526-j9kg00qf 4850 9 prognostic prognostic JJ cord-022526-j9kg00qf 4850 10 factors factor NNS cord-022526-j9kg00qf 4850 11 , , , cord-022526-j9kg00qf 4850 12 particularly particularly RB cord-022526-j9kg00qf 4850 13 those those DT cord-022526-j9kg00qf 4850 14 reflecting reflect VBG cord-022526-j9kg00qf 4850 15 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 4850 16 function function NN cord-022526-j9kg00qf 4850 17 . . . cord-022526-j9kg00qf 4851 1 Simple simple JJ cord-022526-j9kg00qf 4851 2 obstruction obstruction NN cord-022526-j9kg00qf 4851 3 involves involve VBZ cord-022526-j9kg00qf 4851 4 intestinal intestinal JJ cord-022526-j9kg00qf 4851 5 obstruction obstruction NN cord-022526-j9kg00qf 4851 6 of of IN cord-022526-j9kg00qf 4851 7 the the DT cord-022526-j9kg00qf 4851 8 lumen lumen NN cord-022526-j9kg00qf 4851 9 without without IN cord-022526-j9kg00qf 4851 10 obstruction obstruction NN cord-022526-j9kg00qf 4851 11 of of IN cord-022526-j9kg00qf 4851 12 vascular vascular JJ cord-022526-j9kg00qf 4851 13 flow flow NN cord-022526-j9kg00qf 4851 14 . . . cord-022526-j9kg00qf 4852 1 However however RB cord-022526-j9kg00qf 4852 2 , , , cord-022526-j9kg00qf 4852 3 because because IN cord-022526-j9kg00qf 4852 4 a a DT cord-022526-j9kg00qf 4852 5 tremendous tremendous JJ cord-022526-j9kg00qf 4852 6 volume volume NN cord-022526-j9kg00qf 4852 7 of of IN cord-022526-j9kg00qf 4852 8 fluid fluid NN cord-022526-j9kg00qf 4852 9 enters enter VBZ cord-022526-j9kg00qf 4852 10 the the DT cord-022526-j9kg00qf 4852 11 small small JJ cord-022526-j9kg00qf 4852 12 intestinal intestinal JJ cord-022526-j9kg00qf 4852 13 lumen lumen NN cord-022526-j9kg00qf 4852 14 daily daily NN cord-022526-j9kg00qf 4852 15 , , , cord-022526-j9kg00qf 4852 16 31,32 31,32 CD cord-022526-j9kg00qf 4852 17 the the DT cord-022526-j9kg00qf 4852 18 obstructed obstruct VBN cord-022526-j9kg00qf 4852 19 intestine intestine NN cord-022526-j9kg00qf 4852 20 tends tend VBZ cord-022526-j9kg00qf 4852 21 to to TO cord-022526-j9kg00qf 4852 22 become become VB cord-022526-j9kg00qf 4852 23 distended distended JJ cord-022526-j9kg00qf 4852 24 , , , cord-022526-j9kg00qf 4852 25 which which WDT cord-022526-j9kg00qf 4852 26 in in IN cord-022526-j9kg00qf 4852 27 turn turn NN cord-022526-j9kg00qf 4852 28 may may MD cord-022526-j9kg00qf 4852 29 reduce reduce VB cord-022526-j9kg00qf 4852 30 mural mural NN cord-022526-j9kg00qf 4852 31 blood blood NN cord-022526-j9kg00qf 4852 32 flow flow NN cord-022526-j9kg00qf 4852 33 . . . cord-022526-j9kg00qf 4853 1 33 33 CD cord-022526-j9kg00qf 4853 2 Ultimately ultimately RB cord-022526-j9kg00qf 4853 3 , , , cord-022526-j9kg00qf 4853 4 such such JJ cord-022526-j9kg00qf 4853 5 distention distention NN cord-022526-j9kg00qf 4853 6 may may MD cord-022526-j9kg00qf 4853 7 result result VB cord-022526-j9kg00qf 4853 8 in in IN cord-022526-j9kg00qf 4853 9 necrosis necrosis NN cord-022526-j9kg00qf 4853 10 of of IN cord-022526-j9kg00qf 4853 11 tissues tissue NNS cord-022526-j9kg00qf 4853 12 , , , cord-022526-j9kg00qf 4853 13 particularly particularly RB cord-022526-j9kg00qf 4853 14 in in IN cord-022526-j9kg00qf 4853 15 the the DT cord-022526-j9kg00qf 4853 16 immediate immediate JJ cord-022526-j9kg00qf 4853 17 vicinity vicinity NN cord-022526-j9kg00qf 4853 18 of of IN cord-022526-j9kg00qf 4853 19 the the DT cord-022526-j9kg00qf 4853 20 obstruction obstruction NN cord-022526-j9kg00qf 4853 21 . . . cord-022526-j9kg00qf 4854 1 34 34 CD cord-022526-j9kg00qf 4854 2 Few few JJ cord-022526-j9kg00qf 4854 3 are be VBP cord-022526-j9kg00qf 4854 4 the the DT cord-022526-j9kg00qf 4854 5 causes cause NNS cord-022526-j9kg00qf 4854 6 of of IN cord-022526-j9kg00qf 4854 7 simple simple JJ cord-022526-j9kg00qf 4854 8 obstruction obstruction NN cord-022526-j9kg00qf 4854 9 in in IN cord-022526-j9kg00qf 4854 10 the the DT cord-022526-j9kg00qf 4854 11 small small JJ cord-022526-j9kg00qf 4854 12 intestine intestine NN cord-022526-j9kg00qf 4854 13 , , , cord-022526-j9kg00qf 4854 14 and and CC cord-022526-j9kg00qf 4854 15 the the DT cord-022526-j9kg00qf 4854 16 incidence incidence NN cord-022526-j9kg00qf 4854 17 of of IN cord-022526-j9kg00qf 4854 18 these these DT cord-022526-j9kg00qf 4854 19 obstructions obstruction NNS cord-022526-j9kg00qf 4854 20 is be VBZ cord-022526-j9kg00qf 4854 21 low low JJ cord-022526-j9kg00qf 4854 22 ( ( -LRB- cord-022526-j9kg00qf 4854 23 approximately approximately RB cord-022526-j9kg00qf 4854 24 3 3 CD cord-022526-j9kg00qf 4854 25 % % NN cord-022526-j9kg00qf 4854 26 of of IN cord-022526-j9kg00qf 4854 27 all all DT cord-022526-j9kg00qf 4854 28 referred refer VBN cord-022526-j9kg00qf 4854 29 horses horse NNS cord-022526-j9kg00qf 4854 30 in in IN cord-022526-j9kg00qf 4854 31 one one CD cord-022526-j9kg00qf 4854 32 large large JJ cord-022526-j9kg00qf 4854 33 hospital hospital NN cord-022526-j9kg00qf 4854 34 - - HYPH cord-022526-j9kg00qf 4854 35 based base VBN cord-022526-j9kg00qf 4854 36 study study NN cord-022526-j9kg00qf 4854 37 ) ) -RRB- cord-022526-j9kg00qf 4854 38 . . . cord-022526-j9kg00qf 4855 1 5 5 LS cord-022526-j9kg00qf 4856 1 However however RB cord-022526-j9kg00qf 4856 2 , , , cord-022526-j9kg00qf 4856 3 in in IN cord-022526-j9kg00qf 4856 4 some some DT cord-022526-j9kg00qf 4856 5 geographic geographic JJ cord-022526-j9kg00qf 4856 6 regions region NNS cord-022526-j9kg00qf 4856 7 , , , cord-022526-j9kg00qf 4856 8 this this DT cord-022526-j9kg00qf 4856 9 type type NN cord-022526-j9kg00qf 4856 10 of of IN cord-022526-j9kg00qf 4856 11 obstruction obstruction NN cord-022526-j9kg00qf 4856 12 is be VBZ cord-022526-j9kg00qf 4856 13 prevalent prevalent JJ cord-022526-j9kg00qf 4856 14 . . . cord-022526-j9kg00qf 4857 1 For for IN cord-022526-j9kg00qf 4857 2 example example NN cord-022526-j9kg00qf 4857 3 , , , cord-022526-j9kg00qf 4857 4 in in IN cord-022526-j9kg00qf 4857 5 the the DT cord-022526-j9kg00qf 4857 6 southeastern southeastern JJ cord-022526-j9kg00qf 4857 7 United United NNP cord-022526-j9kg00qf 4857 8 States States NNP cord-022526-j9kg00qf 4857 9 , , , cord-022526-j9kg00qf 4857 10 ileal ileal JJ cord-022526-j9kg00qf 4857 11 impactions impaction NNS cord-022526-j9kg00qf 4857 12 are be VBP cord-022526-j9kg00qf 4857 13 common common JJ cord-022526-j9kg00qf 4857 14 . . . cord-022526-j9kg00qf 4858 1 35 35 CD cord-022526-j9kg00qf 4858 2 _SP cord-022526-j9kg00qf 4859 1 Ileal ileal NN cord-022526-j9kg00qf 4859 2 impactions impaction NNS cord-022526-j9kg00qf 4859 3 most most RBS cord-022526-j9kg00qf 4859 4 commonly commonly RB cord-022526-j9kg00qf 4859 5 occur occur VBP cord-022526-j9kg00qf 4859 6 in in IN cord-022526-j9kg00qf 4859 7 adult adult NN cord-022526-j9kg00qf 4859 8 horses horse NNS cord-022526-j9kg00qf 4859 9 in in IN cord-022526-j9kg00qf 4859 10 the the DT cord-022526-j9kg00qf 4859 11 southeastern southeastern JJ cord-022526-j9kg00qf 4859 12 United United NNP cord-022526-j9kg00qf 4859 13 States States NNP cord-022526-j9kg00qf 4859 14 . . . cord-022526-j9kg00qf 4860 1 Although although IN cord-022526-j9kg00qf 4860 2 feeding feed VBG cord-022526-j9kg00qf 4860 3 of of IN cord-022526-j9kg00qf 4860 4 coastal coastal JJ cord-022526-j9kg00qf 4860 5 Bermuda Bermuda NNP cord-022526-j9kg00qf 4860 6 hay hay NN cord-022526-j9kg00qf 4860 7 has have VBZ cord-022526-j9kg00qf 4860 8 been be VBN cord-022526-j9kg00qf 4860 9 implicated implicate VBN cord-022526-j9kg00qf 4860 10 in in IN cord-022526-j9kg00qf 4860 11 the the DT cord-022526-j9kg00qf 4860 12 regional regional JJ cord-022526-j9kg00qf 4860 13 distribution distribution NN cord-022526-j9kg00qf 4860 14 of of IN cord-022526-j9kg00qf 4860 15 the the DT cord-022526-j9kg00qf 4860 16 disease disease NN cord-022526-j9kg00qf 4860 17 , , , cord-022526-j9kg00qf 4860 18 separating separate VBG cord-022526-j9kg00qf 4860 19 geographic geographic JJ cord-022526-j9kg00qf 4860 20 location location NN cord-022526-j9kg00qf 4860 21 from from IN cord-022526-j9kg00qf 4860 22 regional regional JJ cord-022526-j9kg00qf 4860 23 hay hay NN cord-022526-j9kg00qf 4860 24 sources source NNS cord-022526-j9kg00qf 4860 25 as as IN cord-022526-j9kg00qf 4860 26 risk risk NN cord-022526-j9kg00qf 4860 27 factors factor NNS cord-022526-j9kg00qf 4860 28 has have VBZ cord-022526-j9kg00qf 4860 29 been be VBN cord-022526-j9kg00qf 4860 30 difficult difficult JJ cord-022526-j9kg00qf 4860 31 . . . cord-022526-j9kg00qf 4861 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 4861 2 , , , cord-022526-j9kg00qf 4861 3 feeding feed VBG cord-022526-j9kg00qf 4861 4 coastal coastal JJ cord-022526-j9kg00qf 4861 5 Bermuda Bermuda NNP cord-022526-j9kg00qf 4861 6 hay hay NN cord-022526-j9kg00qf 4861 7 likely likely JJ cord-022526-j9kg00qf 4861 8 places place VBZ cord-022526-j9kg00qf 4861 9 horses horse NNS cord-022526-j9kg00qf 4861 10 at at IN cord-022526-j9kg00qf 4861 11 risk risk NN cord-022526-j9kg00qf 4861 12 of of IN cord-022526-j9kg00qf 4861 13 ileal ileal JJ cord-022526-j9kg00qf 4861 14 impaction impaction NN cord-022526-j9kg00qf 4861 15 , , , cord-022526-j9kg00qf 4861 16 particularly particularly RB cord-022526-j9kg00qf 4861 17 if if IN cord-022526-j9kg00qf 4861 18 the the DT cord-022526-j9kg00qf 4861 19 coarse coarse JJ cord-022526-j9kg00qf 4861 20 fiber fiber NN cord-022526-j9kg00qf 4861 21 content content NN cord-022526-j9kg00qf 4861 22 of of IN cord-022526-j9kg00qf 4861 23 the the DT cord-022526-j9kg00qf 4861 24 hay hay NN cord-022526-j9kg00qf 4861 25 is be VBZ cord-022526-j9kg00qf 4861 26 high high JJ cord-022526-j9kg00qf 4861 27 . . . cord-022526-j9kg00qf 4862 1 Furthermore furthermore RB cord-022526-j9kg00qf 4862 2 , , , cord-022526-j9kg00qf 4862 3 sudden sudden JJ cord-022526-j9kg00qf 4862 4 changes change NNS cord-022526-j9kg00qf 4862 5 in in IN cord-022526-j9kg00qf 4862 6 feed feed NN cord-022526-j9kg00qf 4862 7 from from IN cord-022526-j9kg00qf 4862 8 an an DT cord-022526-j9kg00qf 4862 9 alternate alternate JJ cord-022526-j9kg00qf 4862 10 type type NN cord-022526-j9kg00qf 4862 11 of of IN cord-022526-j9kg00qf 4862 12 hay hay NN cord-022526-j9kg00qf 4862 13 to to TO cord-022526-j9kg00qf 4862 14 coastal coastal JJ cord-022526-j9kg00qf 4862 15 Bermuda Bermuda NNP cord-022526-j9kg00qf 4862 16 hay hay NN cord-022526-j9kg00qf 4862 17 likely likely RB cord-022526-j9kg00qf 4862 18 places place VBZ cord-022526-j9kg00qf 4862 19 a a DT cord-022526-j9kg00qf 4862 20 horse horse NN cord-022526-j9kg00qf 4862 21 at at IN cord-022526-j9kg00qf 4862 22 risk risk NN cord-022526-j9kg00qf 4862 23 of of IN cord-022526-j9kg00qf 4862 24 ileal ileal JJ cord-022526-j9kg00qf 4862 25 impaction impaction NN cord-022526-j9kg00qf 4862 26 . . . cord-022526-j9kg00qf 4863 1 38 38 CD cord-022526-j9kg00qf 4863 2 Studies Studies NNPS cord-022526-j9kg00qf 4863 3 in in IN cord-022526-j9kg00qf 4863 4 England England NNP cord-022526-j9kg00qf 4863 5 have have VBP cord-022526-j9kg00qf 4863 6 revealed reveal VBN cord-022526-j9kg00qf 4863 7 tapeworm tapeworm NN cord-022526-j9kg00qf 4863 8 infection infection NN cord-022526-j9kg00qf 4863 9 as as IN cord-022526-j9kg00qf 4863 10 another another DT cord-022526-j9kg00qf 4863 11 important important JJ cord-022526-j9kg00qf 4863 12 risk risk NN cord-022526-j9kg00qf 4863 13 factor factor NN cord-022526-j9kg00qf 4863 14 for for IN cord-022526-j9kg00qf 4863 15 ileal ileal JJ cord-022526-j9kg00qf 4863 16 impaction impaction NN cord-022526-j9kg00qf 4863 17 . . . cord-022526-j9kg00qf 4864 1 Based base VBN cord-022526-j9kg00qf 4864 2 on on IN cord-022526-j9kg00qf 4864 3 risk risk NN cord-022526-j9kg00qf 4864 4 analysis analysis NN cord-022526-j9kg00qf 4864 5 , , , cord-022526-j9kg00qf 4864 6 the the DT cord-022526-j9kg00qf 4864 7 data datum NNS cord-022526-j9kg00qf 4864 8 suggested suggest VBD cord-022526-j9kg00qf 4864 9 that that IN cord-022526-j9kg00qf 4864 10 in in IN cord-022526-j9kg00qf 4864 11 excess excess NN cord-022526-j9kg00qf 4864 12 of of IN cord-022526-j9kg00qf 4864 13 80 80 CD cord-022526-j9kg00qf 4864 14 % % NN cord-022526-j9kg00qf 4864 15 of of IN cord-022526-j9kg00qf 4864 16 the the DT cord-022526-j9kg00qf 4864 17 ileal ileal JJ cord-022526-j9kg00qf 4864 18 impaction impaction NN cord-022526-j9kg00qf 4864 19 cases case NNS cord-022526-j9kg00qf 4864 20 studied study VBN cord-022526-j9kg00qf 4864 21 were be VBD cord-022526-j9kg00qf 4864 22 associated associate VBN cord-022526-j9kg00qf 4864 23 with with IN cord-022526-j9kg00qf 4864 24 serologic serologic NN cord-022526-j9kg00qf 4864 25 or or CC cord-022526-j9kg00qf 4864 26 fecal fecal JJ cord-022526-j9kg00qf 4864 27 evidence evidence NN cord-022526-j9kg00qf 4864 28 of of IN cord-022526-j9kg00qf 4864 29 tapeworm tapeworm NN cord-022526-j9kg00qf 4864 30 infection infection NN cord-022526-j9kg00qf 4864 31 . . . cord-022526-j9kg00qf 4865 1 39 39 CD cord-022526-j9kg00qf 4866 1 Because because IN cord-022526-j9kg00qf 4866 2 of of IN cord-022526-j9kg00qf 4866 3 the the DT cord-022526-j9kg00qf 4866 4 poor poor JJ cord-022526-j9kg00qf 4866 5 sensitivity sensitivity NN cord-022526-j9kg00qf 4866 6 of of IN cord-022526-j9kg00qf 4866 7 fecal fecal JJ cord-022526-j9kg00qf 4866 8 analysis analysis NN cord-022526-j9kg00qf 4866 9 for for IN cord-022526-j9kg00qf 4866 10 tapeworms tapeworm NNS cord-022526-j9kg00qf 4866 11 , , , cord-022526-j9kg00qf 4866 12 Proudman Proudman NNP cord-022526-j9kg00qf 4866 13 and and CC cord-022526-j9kg00qf 4866 14 Trees tree NNS cord-022526-j9kg00qf 4866 15 have have VBP cord-022526-j9kg00qf 4866 16 developed develop VBN cord-022526-j9kg00qf 4866 17 a a DT cord-022526-j9kg00qf 4866 18 serologic serologic JJ cord-022526-j9kg00qf 4866 19 test test NN cord-022526-j9kg00qf 4866 20 ( ( -LRB- cord-022526-j9kg00qf 4866 21 enzyme enzyme NN cord-022526-j9kg00qf 4866 22 - - HYPH cord-022526-j9kg00qf 4866 23 linked link VBN cord-022526-j9kg00qf 4866 24 immunosorbent immunosorbent JJ cord-022526-j9kg00qf 4866 25 assay assay NN cord-022526-j9kg00qf 4866 26 ) ) -RRB- cord-022526-j9kg00qf 4866 27 with with IN cord-022526-j9kg00qf 4866 28 a a DT cord-022526-j9kg00qf 4866 29 sensitivity sensitivity NN cord-022526-j9kg00qf 4866 30 of of IN cord-022526-j9kg00qf 4866 31 approximately approximately RB cord-022526-j9kg00qf 4866 32 70 70 CD cord-022526-j9kg00qf 4866 33 % % NN cord-022526-j9kg00qf 4866 34 and and CC cord-022526-j9kg00qf 4866 35 a a DT cord-022526-j9kg00qf 4866 36 specificity specificity NN cord-022526-j9kg00qf 4866 37 of of IN cord-022526-j9kg00qf 4866 38 95 95 CD cord-022526-j9kg00qf 4866 39 % % NN cord-022526-j9kg00qf 4866 40 . . . cord-022526-j9kg00qf 4867 1 40 40 CD cord-022526-j9kg00qf 4867 2 Clinical clinical JJ cord-022526-j9kg00qf 4867 3 signs sign NNS cord-022526-j9kg00qf 4867 4 of of IN cord-022526-j9kg00qf 4867 5 horses horse NNS cord-022526-j9kg00qf 4867 6 with with IN cord-022526-j9kg00qf 4867 7 ileal ileal JJ cord-022526-j9kg00qf 4867 8 impaction impaction NN cord-022526-j9kg00qf 4867 9 are be VBP cord-022526-j9kg00qf 4867 10 typical typical JJ cord-022526-j9kg00qf 4867 11 for for IN cord-022526-j9kg00qf 4867 12 a a DT cord-022526-j9kg00qf 4867 13 horse horse NN cord-022526-j9kg00qf 4867 14 with with IN cord-022526-j9kg00qf 4867 15 small small JJ cord-022526-j9kg00qf 4867 16 intestinal intestinal JJ cord-022526-j9kg00qf 4867 17 obstruction obstruction NN cord-022526-j9kg00qf 4867 18 , , , cord-022526-j9kg00qf 4867 19 including include VBG cord-022526-j9kg00qf 4867 20 onset onset NN cord-022526-j9kg00qf 4867 21 of of IN cord-022526-j9kg00qf 4867 22 moderate moderate JJ cord-022526-j9kg00qf 4867 23 to to IN cord-022526-j9kg00qf 4867 24 severe severe JJ cord-022526-j9kg00qf 4867 25 colic colic NN cord-022526-j9kg00qf 4867 26 and and CC cord-022526-j9kg00qf 4867 27 loops loop NNS cord-022526-j9kg00qf 4867 28 of of IN cord-022526-j9kg00qf 4867 29 distended distended JJ cord-022526-j9kg00qf 4867 30 small small JJ cord-022526-j9kg00qf 4867 31 intestine intestine NN cord-022526-j9kg00qf 4867 32 palpable palpable NN cord-022526-j9kg00qf 4867 33 per per IN cord-022526-j9kg00qf 4867 34 rectum rectum NN cord-022526-j9kg00qf 4867 35 as as IN cord-022526-j9kg00qf 4867 36 the the DT cord-022526-j9kg00qf 4867 37 condition condition NN cord-022526-j9kg00qf 4867 38 progresses progress VBZ cord-022526-j9kg00qf 4867 39 . . . cord-022526-j9kg00qf 4868 1 Because because IN cord-022526-j9kg00qf 4868 2 the the DT cord-022526-j9kg00qf 4868 3 ileum ileum NN cord-022526-j9kg00qf 4868 4 is be VBZ cord-022526-j9kg00qf 4868 5 the the DT cord-022526-j9kg00qf 4868 6 distal distal JJ cord-022526-j9kg00qf 4868 7 most most JJS cord-022526-j9kg00qf 4868 8 aspect aspect NN cord-022526-j9kg00qf 4868 9 of of IN cord-022526-j9kg00qf 4868 10 the the DT cord-022526-j9kg00qf 4868 11 small small JJ cord-022526-j9kg00qf 4868 12 intestinal intestinal JJ cord-022526-j9kg00qf 4868 13 tract tract NN cord-022526-j9kg00qf 4868 14 , , , cord-022526-j9kg00qf 4868 15 nasogastric nasogastric NN cord-022526-j9kg00qf 4868 16 reflux reflux NN cord-022526-j9kg00qf 4868 17 may may MD cord-022526-j9kg00qf 4868 18 take take VB cord-022526-j9kg00qf 4868 19 a a DT cord-022526-j9kg00qf 4868 20 considerable considerable JJ cord-022526-j9kg00qf 4868 21 time time NN cord-022526-j9kg00qf 4868 22 to to TO cord-022526-j9kg00qf 4868 23 develop develop VB cord-022526-j9kg00qf 4868 24 and and CC cord-022526-j9kg00qf 4868 25 is be VBZ cord-022526-j9kg00qf 4868 26 found find VBN cord-022526-j9kg00qf 4868 27 in in IN cord-022526-j9kg00qf 4868 28 approximately approximately RB cord-022526-j9kg00qf 4868 29 50 50 CD cord-022526-j9kg00qf 4868 30 % % NN cord-022526-j9kg00qf 4868 31 of of IN cord-022526-j9kg00qf 4868 32 horses horse NNS cord-022526-j9kg00qf 4868 33 requiring require VBG cord-022526-j9kg00qf 4868 34 surgical surgical JJ cord-022526-j9kg00qf 4868 35 correction correction NN cord-022526-j9kg00qf 4868 36 of of IN cord-022526-j9kg00qf 4868 37 impacted impact VBN cord-022526-j9kg00qf 4868 38 ileum ileum NN cord-022526-j9kg00qf 4868 39 . . . cord-022526-j9kg00qf 4869 1 35 35 CD cord-022526-j9kg00qf 4869 2 , , , cord-022526-j9kg00qf 4869 3 41 41 CD cord-022526-j9kg00qf 4869 4 One one CD cord-022526-j9kg00qf 4869 5 usually usually RB cord-022526-j9kg00qf 4869 6 makes make VBZ cord-022526-j9kg00qf 4869 7 the the DT cord-022526-j9kg00qf 4869 8 diagnosis diagnosis NN cord-022526-j9kg00qf 4869 9 at at IN cord-022526-j9kg00qf 4869 10 surgery surgery NN cord-022526-j9kg00qf 4869 11 , , , cord-022526-j9kg00qf 4869 12 although although IN cord-022526-j9kg00qf 4869 13 on on IN cord-022526-j9kg00qf 4869 14 occasion occasion NN cord-022526-j9kg00qf 4869 15 one one PRP cord-022526-j9kg00qf 4869 16 may may MD cord-022526-j9kg00qf 4869 17 palpate palpate VB cord-022526-j9kg00qf 4869 18 an an DT cord-022526-j9kg00qf 4869 19 impacted impact VBN cord-022526-j9kg00qf 4869 20 ileum ileum NN cord-022526-j9kg00qf 4869 21 per per IN cord-022526-j9kg00qf 4869 22 rectum rectum NN cord-022526-j9kg00qf 4869 23 . . . cord-022526-j9kg00qf 4870 1 Multiple multiple JJ cord-022526-j9kg00qf 4870 2 loops loop NNS cord-022526-j9kg00qf 4870 3 of of IN cord-022526-j9kg00qf 4870 4 distended distended JJ cord-022526-j9kg00qf 4870 5 small small JJ cord-022526-j9kg00qf 4870 6 intestine intestine NN cord-022526-j9kg00qf 4870 7 frequently frequently RB cord-022526-j9kg00qf 4870 8 make make VBP cord-022526-j9kg00qf 4870 9 the the DT cord-022526-j9kg00qf 4870 10 impaction impaction NN cord-022526-j9kg00qf 4870 11 difficult difficult JJ cord-022526-j9kg00qf 4870 12 to to TO cord-022526-j9kg00qf 4870 13 palpate palpate VB cord-022526-j9kg00qf 4870 14 . . . cord-022526-j9kg00qf 4871 1 Ileal ileal NN cord-022526-j9kg00qf 4871 2 impactions impaction NNS cord-022526-j9kg00qf 4871 3 may may MD cord-022526-j9kg00qf 4871 4 resolve resolve VB cord-022526-j9kg00qf 4871 5 with with IN cord-022526-j9kg00qf 4871 6 medical medical JJ cord-022526-j9kg00qf 4871 7 treatment treatment NN cord-022526-j9kg00qf 4871 8 36 36 CD cord-022526-j9kg00qf 4871 9 but but CC cord-022526-j9kg00qf 4871 10 frequently frequently RB cord-022526-j9kg00qf 4871 11 require require VBP cord-022526-j9kg00qf 4871 12 surgical surgical JJ cord-022526-j9kg00qf 4871 13 intervention intervention NN cord-022526-j9kg00qf 4871 14 ( ( -LRB- cord-022526-j9kg00qf 4871 15 Figure Figure NNP cord-022526-j9kg00qf 4871 16 13.15 13.15 CD cord-022526-j9kg00qf 4871 17 - - SYM cord-022526-j9kg00qf 4871 18 2 2 CD cord-022526-j9kg00qf 4871 19 ) ) -RRB- cord-022526-j9kg00qf 4871 20 . . . cord-022526-j9kg00qf 4872 1 At at IN cord-022526-j9kg00qf 4872 2 surgery surgery NN cord-022526-j9kg00qf 4872 3 , , , cord-022526-j9kg00qf 4872 4 one one PRP cord-022526-j9kg00qf 4872 5 can can MD cord-022526-j9kg00qf 4872 6 infuse infuse VB cord-022526-j9kg00qf 4872 7 fluids fluid NNS cord-022526-j9kg00qf 4872 8 directly directly RB cord-022526-j9kg00qf 4872 9 Figure figure NN cord-022526-j9kg00qf 4872 10 13 13 CD cord-022526-j9kg00qf 4872 11 .15 .15 CD cord-022526-j9kg00qf 4872 12 - - SYM cord-022526-j9kg00qf 4872 13 1 1 CD cord-022526-j9kg00qf 4872 14 Appearance appearance NN cord-022526-j9kg00qf 4872 15 of of IN cord-022526-j9kg00qf 4872 16 roundworms roundworm NNS cord-022526-j9kg00qf 4872 17 that that WDT cord-022526-j9kg00qf 4872 18 have have VBP cord-022526-j9kg00qf 4872 19 been be VBN cord-022526-j9kg00qf 4872 20 retrieved retrieve VBN cord-022526-j9kg00qf 4872 21 within within IN cord-022526-j9kg00qf 4872 22 the the DT cord-022526-j9kg00qf 4872 23 nasogastric nasogastric NN cord-022526-j9kg00qf 4872 24 reflux reflux NN cord-022526-j9kg00qf 4872 25 from from IN cord-022526-j9kg00qf 4872 26 a a DT cord-022526-j9kg00qf 4872 27 foal foal NN cord-022526-j9kg00qf 4872 28 with with IN cord-022526-j9kg00qf 4872 29 an an DT cord-022526-j9kg00qf 4872 30 ascarid ascarid JJ cord-022526-j9kg00qf 4872 31 impaction impaction NN cord-022526-j9kg00qf 4872 32 . . . cord-022526-j9kg00qf 4873 1 The the DT cord-022526-j9kg00qf 4873 2 large large JJ cord-022526-j9kg00qf 4873 3 size size NN cord-022526-j9kg00qf 4873 4 of of IN cord-022526-j9kg00qf 4873 5 these these DT cord-022526-j9kg00qf 4873 6 ascarids ascarid NNS cord-022526-j9kg00qf 4873 7 ( ( -LRB- cord-022526-j9kg00qf 4873 8 bar bar NN cord-022526-j9kg00qf 4873 9 = = SYM cord-022526-j9kg00qf 4873 10 1 1 CD cord-022526-j9kg00qf 4873 11 cm cm NN cord-022526-j9kg00qf 4873 12 ) ) -RRB- cord-022526-j9kg00qf 4873 13 contributes contribute VBZ cord-022526-j9kg00qf 4873 14 to to IN cord-022526-j9kg00qf 4873 15 the the DT cord-022526-j9kg00qf 4873 16 risk risk NN cord-022526-j9kg00qf 4873 17 of of IN cord-022526-j9kg00qf 4873 18 impaction impaction NN cord-022526-j9kg00qf 4873 19 following follow VBG cord-022526-j9kg00qf 4873 20 sudden sudden JJ cord-022526-j9kg00qf 4873 21 kills kill NNS cord-022526-j9kg00qf 4873 22 of of IN cord-022526-j9kg00qf 4873 23 these these DT cord-022526-j9kg00qf 4873 24 parasites parasite NNS cord-022526-j9kg00qf 4873 25 by by IN cord-022526-j9kg00qf 4873 26 broad broad JJ cord-022526-j9kg00qf 4873 27 - - HYPH cord-022526-j9kg00qf 4873 28 spectrum spectrum NN cord-022526-j9kg00qf 4873 29 anthelmintics anthelmintic NNS cord-022526-j9kg00qf 4873 30 . . . cord-022526-j9kg00qf 4874 1 into into IN cord-022526-j9kg00qf 4874 2 the the DT cord-022526-j9kg00qf 4874 3 mass mass NN cord-022526-j9kg00qf 4874 4 , , , cord-022526-j9kg00qf 4874 5 allowing allow VBG cord-022526-j9kg00qf 4874 6 the the DT cord-022526-j9kg00qf 4874 7 surgeon surgeon NN cord-022526-j9kg00qf 4874 8 to to TO cord-022526-j9kg00qf 4874 9 breakdown breakdown VB cord-022526-j9kg00qf 4874 10 the the DT cord-022526-j9kg00qf 4874 11 impaction impaction NN cord-022526-j9kg00qf 4874 12 . . . cord-022526-j9kg00qf 4875 1 The the DT cord-022526-j9kg00qf 4875 2 surgeon surgeon NN cord-022526-j9kg00qf 4875 3 may may MD cord-022526-j9kg00qf 4875 4 include include VB cord-022526-j9kg00qf 4875 5 dioctyl dioctyl NNP cord-022526-j9kg00qf 4875 6 sodium sodium NN cord-022526-j9kg00qf 4875 7 sulfosuccinate sulfosuccinate NNP cord-022526-j9kg00qf 4875 8 in in IN cord-022526-j9kg00qf 4875 9 the the DT cord-022526-j9kg00qf 4875 10 infused infuse VBN cord-022526-j9kg00qf 4875 11 fluid fluid NN cord-022526-j9kg00qf 4875 12 to to TO cord-022526-j9kg00qf 4875 13 aid aid VB cord-022526-j9kg00qf 4875 14 in in IN cord-022526-j9kg00qf 4875 15 disruption disruption NN cord-022526-j9kg00qf 4875 16 of of IN cord-022526-j9kg00qf 4875 17 the the DT cord-022526-j9kg00qf 4875 18 mass mass NN cord-022526-j9kg00qf 4875 19 . . . cord-022526-j9kg00qf 4876 1 Extensive extensive JJ cord-022526-j9kg00qf 4876 2 small small JJ cord-022526-j9kg00qf 4876 3 intestinal intestinal JJ cord-022526-j9kg00qf 4876 4 distention distention NN cord-022526-j9kg00qf 4876 5 and and CC cord-022526-j9kg00qf 4876 6 intraoperative intraoperative JJ cord-022526-j9kg00qf 4876 7 manipulation manipulation NN cord-022526-j9kg00qf 4876 8 of of IN cord-022526-j9kg00qf 4876 9 the the DT cord-022526-j9kg00qf 4876 10 ileum ileum NN cord-022526-j9kg00qf 4876 11 may may MD cord-022526-j9kg00qf 4876 12 lead lead VB cord-022526-j9kg00qf 4876 13 to to IN cord-022526-j9kg00qf 4876 14 postoperative postoperative JJ cord-022526-j9kg00qf 4876 15 ileus ileus NN cord-022526-j9kg00qf 4876 16 , , , cord-022526-j9kg00qf 4876 17 42 42 CD cord-022526-j9kg00qf 4876 18 but but CC cord-022526-j9kg00qf 4877 1 recent recent JJ cord-022526-j9kg00qf 4877 2 studies study NNS cord-022526-j9kg00qf 4877 3 indicate indicate VBP cord-022526-j9kg00qf 4877 4 that that IN cord-022526-j9kg00qf 4877 5 this this DT cord-022526-j9kg00qf 4877 6 complication complication NN cord-022526-j9kg00qf 4877 7 is be VBZ cord-022526-j9kg00qf 4877 8 less less RBR cord-022526-j9kg00qf 4877 9 frequent frequent JJ cord-022526-j9kg00qf 4877 10 as as IN cord-022526-j9kg00qf 4877 11 the the DT cord-022526-j9kg00qf 4877 12 duration duration NN cord-022526-j9kg00qf 4877 13 of of IN cord-022526-j9kg00qf 4877 14 disease disease NN cord-022526-j9kg00qf 4877 15 before before IN cord-022526-j9kg00qf 4877 16 admission admission NN cord-022526-j9kg00qf 4877 17 decreases decrease VBZ cord-022526-j9kg00qf 4877 18 . . . cord-022526-j9kg00qf 4878 1 35 35 CD cord-022526-j9kg00qf 4878 2 Recent recent JJ cord-022526-j9kg00qf 4878 3 studies study NNS cord-022526-j9kg00qf 4878 4 indicate indicate VBP cord-022526-j9kg00qf 4878 5 that that IN cord-022526-j9kg00qf 4878 6 the the DT cord-022526-j9kg00qf 4878 7 prognosis prognosis NN cord-022526-j9kg00qf 4878 8 for for IN cord-022526-j9kg00qf 4878 9 survival survival NN cord-022526-j9kg00qf 4878 10 is be VBZ cord-022526-j9kg00qf 4878 11 good good JJ cord-022526-j9kg00qf 4878 12 . . . cord-022526-j9kg00qf 4879 1 35 35 CD cord-022526-j9kg00qf 4879 2 , , , cord-022526-j9kg00qf 4879 3 36 36 CD cord-022526-j9kg00qf 4879 4 _SP cord-022526-j9kg00qf 4879 5 Ileal Ileal NNP cord-022526-j9kg00qf 4879 6 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4879 7 is be VBZ cord-022526-j9kg00qf 4879 8 a a DT cord-022526-j9kg00qf 4879 9 disorder disorder NN cord-022526-j9kg00qf 4879 10 in in IN cord-022526-j9kg00qf 4879 11 which which WDT cord-022526-j9kg00qf 4879 12 the the DT cord-022526-j9kg00qf 4879 13 muscular muscular JJ cord-022526-j9kg00qf 4879 14 layers layer NNS cord-022526-j9kg00qf 4879 15 ( ( -LRB- cord-022526-j9kg00qf 4879 16 circular circular JJ cord-022526-j9kg00qf 4879 17 and and CC cord-022526-j9kg00qf 4879 18 longitudinal longitudinal JJ cord-022526-j9kg00qf 4879 19 ) ) -RRB- cord-022526-j9kg00qf 4879 20 of of IN cord-022526-j9kg00qf 4879 21 the the DT cord-022526-j9kg00qf 4879 22 ileum ileum JJ cord-022526-j9kg00qf 4879 23 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4879 24 for for IN cord-022526-j9kg00qf 4879 25 unknown unknown JJ cord-022526-j9kg00qf 4879 26 reasons reason NNS cord-022526-j9kg00qf 4879 27 ( ( -LRB- cord-022526-j9kg00qf 4879 28 idiopathic idiopathic JJ cord-022526-j9kg00qf 4879 29 ) ) -RRB- cord-022526-j9kg00qf 4879 30 or or CC cord-022526-j9kg00qf 4879 31 following follow VBG cord-022526-j9kg00qf 4879 32 an an DT cord-022526-j9kg00qf 4879 33 incomplete incomplete JJ cord-022526-j9kg00qf 4879 34 or or CC cord-022526-j9kg00qf 4879 35 functional functional JJ cord-022526-j9kg00qf 4879 36 obstruction obstruction NN cord-022526-j9kg00qf 4879 37 . . . cord-022526-j9kg00qf 4880 1 For for IN cord-022526-j9kg00qf 4880 2 idiopathic idiopathic JJ cord-022526-j9kg00qf 4880 3 cases case NNS cord-022526-j9kg00qf 4880 4 , , , cord-022526-j9kg00qf 4880 5 proposed propose VBN cord-022526-j9kg00qf 4880 6 mechanisms mechanism NNS cord-022526-j9kg00qf 4880 7 include include VBP cord-022526-j9kg00qf 4880 8 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 4880 9 neural neural JJ cord-022526-j9kg00qf 4880 10 dysfunction dysfunction NN cord-022526-j9kg00qf 4880 11 resulting result VBG cord-022526-j9kg00qf 4880 12 in in IN cord-022526-j9kg00qf 4880 13 chronically chronically RB cord-022526-j9kg00qf 4880 14 increased increase VBN cord-022526-j9kg00qf 4880 15 muscle muscle NN cord-022526-j9kg00qf 4880 16 tone tone NN cord-022526-j9kg00qf 4880 17 and and CC cord-022526-j9kg00qf 4880 18 subsequent subsequent JJ cord-022526-j9kg00qf 4880 19 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4880 20 of of IN cord-022526-j9kg00qf 4880 21 the the DT cord-022526-j9kg00qf 4880 22 muscular muscular JJ cord-022526-j9kg00qf 4880 23 layers layer NNS cord-022526-j9kg00qf 4880 24 of of IN cord-022526-j9kg00qf 4880 25 the the DT cord-022526-j9kg00qf 4880 26 ileal ileal JJ cord-022526-j9kg00qf 4880 27 wall wall NN cord-022526-j9kg00qf 4880 28 . . . cord-022526-j9kg00qf 4881 1 Such such JJ cord-022526-j9kg00qf 4881 2 neural neural JJ cord-022526-j9kg00qf 4881 3 dysfunction dysfunction NN cord-022526-j9kg00qf 4881 4 possibly possibly RB cord-022526-j9kg00qf 4881 5 could could MD cord-022526-j9kg00qf 4881 6 result result VB cord-022526-j9kg00qf 4881 7 from from IN cord-022526-j9kg00qf 4881 8 parasite parasite NN cord-022526-j9kg00qf 4881 9 migration migration NN cord-022526-j9kg00qf 4881 10 . . . cord-022526-j9kg00qf 4882 1 Alternative alternative JJ cord-022526-j9kg00qf 4882 2 hypotheses hypothesis NNS cord-022526-j9kg00qf 4882 3 include include VBP cord-022526-j9kg00qf 4882 4 chronic chronic JJ cord-022526-j9kg00qf 4882 5 increases increase NNS cord-022526-j9kg00qf 4882 6 in in IN cord-022526-j9kg00qf 4882 7 the the DT cord-022526-j9kg00qf 4882 8 muscular muscular JJ cord-022526-j9kg00qf 4882 9 tone tone NN cord-022526-j9kg00qf 4882 10 of of IN cord-022526-j9kg00qf 4882 11 the the DT cord-022526-j9kg00qf 4882 12 ileocecal ileocecal JJ cord-022526-j9kg00qf 4882 13 valve valve NN cord-022526-j9kg00qf 4882 14 , , , cord-022526-j9kg00qf 4882 15 leading lead VBG cord-022526-j9kg00qf 4882 16 to to IN cord-022526-j9kg00qf 4882 17 muscular muscular JJ cord-022526-j9kg00qf 4882 18 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4882 19 of of IN cord-022526-j9kg00qf 4882 20 the the DT cord-022526-j9kg00qf 4882 21 ileum ileum NN cord-022526-j9kg00qf 4882 22 as as IN cord-022526-j9kg00qf 4882 23 it -PRON- PRP cord-022526-j9kg00qf 4882 24 contracts contract VBZ cord-022526-j9kg00qf 4882 25 against against IN cord-022526-j9kg00qf 4882 26 a a DT cord-022526-j9kg00qf 4882 27 partially partially RB cord-022526-j9kg00qf 4882 28 occluded occlude VBN cord-022526-j9kg00qf 4882 29 ileocecal ileocecal JJ cord-022526-j9kg00qf 4882 30 valve valve NN cord-022526-j9kg00qf 4882 31 . . . cord-022526-j9kg00qf 4883 1 The the DT cord-022526-j9kg00qf 4883 2 jejunum jejunum NNS cord-022526-j9kg00qf 4883 3 also also RB cord-022526-j9kg00qf 4883 4 may may MD cord-022526-j9kg00qf 4883 5 be be VB cord-022526-j9kg00qf 4883 6 hypertrophied hypertrophied JJ cord-022526-j9kg00qf 4883 7 , , , cord-022526-j9kg00qf 4883 8 alone alone JJ cord-022526-j9kg00qf 4883 9 or or CC cord-022526-j9kg00qf 4883 10 with with IN cord-022526-j9kg00qf 4883 11 the the DT cord-022526-j9kg00qf 4883 12 ileum ileum NN cord-022526-j9kg00qf 4883 13 . . . cord-022526-j9kg00qf 4884 1 Clinical clinical JJ cord-022526-j9kg00qf 4884 2 signs sign NNS cord-022526-j9kg00qf 4884 3 include include VBP cord-022526-j9kg00qf 4884 4 chronic chronic JJ cord-022526-j9kg00qf 4884 5 intermittent intermittent JJ cord-022526-j9kg00qf 4884 6 colic colic NN cord-022526-j9kg00qf 4884 7 as as IN cord-022526-j9kg00qf 4884 8 the the DT cord-022526-j9kg00qf 4884 9 ileum ileum NN cord-022526-j9kg00qf 4884 10 hypertrophies hypertrophy NNS cord-022526-j9kg00qf 4884 11 and and CC cord-022526-j9kg00qf 4884 12 gradually gradually RB cord-022526-j9kg00qf 4884 13 narrows narrow VBZ cord-022526-j9kg00qf 4884 14 the the DT cord-022526-j9kg00qf 4884 15 lumen lumen NN cord-022526-j9kg00qf 4884 16 diameter diameter NN cord-022526-j9kg00qf 4884 17 . . . cord-022526-j9kg00qf 4885 1 In in IN cord-022526-j9kg00qf 4885 2 one one CD cord-022526-j9kg00qf 4885 3 study study NN cord-022526-j9kg00qf 4885 4 , , , cord-022526-j9kg00qf 4885 5 partial partial JJ cord-022526-j9kg00qf 4885 6 anorexia anorexia NN cord-022526-j9kg00qf 4885 7 and and CC cord-022526-j9kg00qf 4885 8 chronic chronic JJ cord-022526-j9kg00qf 4885 9 weight weight NN cord-022526-j9kg00qf 4885 10 loss loss NN cord-022526-j9kg00qf 4885 11 ( ( -LRB- cord-022526-j9kg00qf 4885 12 1 1 CD cord-022526-j9kg00qf 4885 13 to to IN cord-022526-j9kg00qf 4885 14 6 6 CD cord-022526-j9kg00qf 4885 15 months month NNS cord-022526-j9kg00qf 4885 16 ) ) -RRB- cord-022526-j9kg00qf 4885 17 were be VBD cord-022526-j9kg00qf 4885 18 documented document VBN cord-022526-j9kg00qf 4885 19 in in IN cord-022526-j9kg00qf 4885 20 45 45 CD cord-022526-j9kg00qf 4885 21 % % NN cord-022526-j9kg00qf 4885 22 of of IN cord-022526-j9kg00qf 4885 23 the the DT cord-022526-j9kg00qf 4885 24 horses horse NNS cord-022526-j9kg00qf 4885 25 , , , cord-022526-j9kg00qf 4885 26 most most RBS cord-022526-j9kg00qf 4885 27 likely likely JJ cord-022526-j9kg00qf 4885 28 because because IN cord-022526-j9kg00qf 4885 29 of of IN cord-022526-j9kg00qf 4885 30 intermittent intermittent JJ cord-022526-j9kg00qf 4885 31 colic colic NN cord-022526-j9kg00qf 4885 32 and and CC cord-022526-j9kg00qf 4885 33 reduced reduce VBN cord-022526-j9kg00qf 4885 34 appetite appetite NN cord-022526-j9kg00qf 4885 35 . . . cord-022526-j9kg00qf 4886 1 Because because IN cord-022526-j9kg00qf 4886 2 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4886 3 does do VBZ cord-022526-j9kg00qf 4886 4 not not RB cord-022526-j9kg00qf 4886 5 affect affect VB cord-022526-j9kg00qf 4886 6 the the DT cord-022526-j9kg00qf 4886 7 ileal ileal JJ cord-022526-j9kg00qf 4886 8 mucosa mucosa NN cord-022526-j9kg00qf 4886 9 , , , cord-022526-j9kg00qf 4886 10 no no DT cord-022526-j9kg00qf 4886 11 reason reason NN cord-022526-j9kg00qf 4886 12 exists exist VBZ cord-022526-j9kg00qf 4886 13 to to TO cord-022526-j9kg00qf 4886 14 believe believe VB cord-022526-j9kg00qf 4886 15 that that IN cord-022526-j9kg00qf 4886 16 these these DT cord-022526-j9kg00qf 4886 17 horses horse NNS cord-022526-j9kg00qf 4886 18 experience experience VBP cord-022526-j9kg00qf 4886 19 malabsorption malabsorption NN cord-022526-j9kg00qf 4886 20 of of IN cord-022526-j9kg00qf 4886 21 nutrients nutrient NNS cord-022526-j9kg00qf 4886 22 . . . cord-022526-j9kg00qf 4887 1 One one CD cord-022526-j9kg00qf 4887 2 usually usually RB cord-022526-j9kg00qf 4887 3 makes make VBZ cord-022526-j9kg00qf 4887 4 the the DT cord-022526-j9kg00qf 4887 5 diagnosis diagnosis NN cord-022526-j9kg00qf 4887 6 at at IN cord-022526-j9kg00qf 4887 7 surgery surgery NN cord-022526-j9kg00qf 4887 8 , , , cord-022526-j9kg00qf 4887 9 although although IN cord-022526-j9kg00qf 4887 10 one one PRP cord-022526-j9kg00qf 4887 11 may may MD cord-022526-j9kg00qf 4887 12 palpate palpate VB cord-022526-j9kg00qf 4887 13 the the DT cord-022526-j9kg00qf 4887 14 hypertophied hypertophie VBN cord-022526-j9kg00qf 4887 15 ileum ileum NN cord-022526-j9kg00qf 4887 16 per per IN cord-022526-j9kg00qf 4887 17 rectum rectum NN cord-022526-j9kg00qf 4887 18 in in IN cord-022526-j9kg00qf 4887 19 some some DT cord-022526-j9kg00qf 4887 20 cases case NNS cord-022526-j9kg00qf 4887 21 . . . cord-022526-j9kg00qf 4888 1 For for IN cord-022526-j9kg00qf 4888 2 treatment treatment NN cord-022526-j9kg00qf 4888 3 , , , cord-022526-j9kg00qf 4888 4 one one PRP cord-022526-j9kg00qf 4888 5 performs perform VBZ cord-022526-j9kg00qf 4888 6 an an DT cord-022526-j9kg00qf 4888 7 ileocecal ileocecal JJ cord-022526-j9kg00qf 4888 8 or or CC cord-022526-j9kg00qf 4888 9 jejunocecal jejunocecal JJ cord-022526-j9kg00qf 4888 10 anastomosis anastomosis NN cord-022526-j9kg00qf 4888 11 to to TO cord-022526-j9kg00qf 4888 12 bypass bypass VB cord-022526-j9kg00qf 4888 13 the the DT cord-022526-j9kg00qf 4888 14 hypertrophied hypertrophied JJ cord-022526-j9kg00qf 4888 15 ileum ileum NN cord-022526-j9kg00qf 4888 16 . . . cord-022526-j9kg00qf 4889 1 Without without IN cord-022526-j9kg00qf 4889 2 surgical surgical JJ cord-022526-j9kg00qf 4889 3 bypass bypass NN cord-022526-j9kg00qf 4889 4 , , , cord-022526-j9kg00qf 4889 5 intermittent intermittent JJ cord-022526-j9kg00qf 4889 6 colic colic NN cord-022526-j9kg00qf 4889 7 persists persist VBZ cord-022526-j9kg00qf 4889 8 and and CC cord-022526-j9kg00qf 4889 9 the the DT cord-022526-j9kg00qf 4889 10 thickened thickened JJ cord-022526-j9kg00qf 4889 11 ileum ileum NN cord-022526-j9kg00qf 4889 12 ultimately ultimately RB cord-022526-j9kg00qf 4889 13 may may MD cord-022526-j9kg00qf 4889 14 rupture rupture VB cord-022526-j9kg00qf 4889 15 . . . cord-022526-j9kg00qf 4890 1 43 43 CD cord-022526-j9kg00qf 4891 1 The the DT cord-022526-j9kg00qf 4891 2 prognosis prognosis NN cord-022526-j9kg00qf 4891 3 is be VBZ cord-022526-j9kg00qf 4891 4 fair fair JJ cord-022526-j9kg00qf 4891 5 with with IN cord-022526-j9kg00qf 4891 6 surgical surgical JJ cord-022526-j9kg00qf 4891 7 treatment treatment NN cord-022526-j9kg00qf 4891 8 . . . cord-022526-j9kg00qf 4892 1 44 44 CD cord-022526-j9kg00qf 4892 2 Secondary secondary JJ cord-022526-j9kg00qf 4892 3 ileal ileal JJ cord-022526-j9kg00qf 4892 4 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4892 5 is be VBZ cord-022526-j9kg00qf 4892 6 most most RBS cord-022526-j9kg00qf 4892 7 commonly commonly RB cord-022526-j9kg00qf 4892 8 notable notable JJ cord-022526-j9kg00qf 4892 9 in in IN cord-022526-j9kg00qf 4892 10 horses horse NNS cord-022526-j9kg00qf 4892 11 that that WDT cord-022526-j9kg00qf 4892 12 previously previously RB cord-022526-j9kg00qf 4892 13 have have VBP cord-022526-j9kg00qf 4892 14 had have VBN cord-022526-j9kg00qf 4892 15 colic colic NN cord-022526-j9kg00qf 4892 16 surgery surgery NN cord-022526-j9kg00qf 4892 17 and and CC cord-022526-j9kg00qf 4892 18 that that WDT cord-022526-j9kg00qf 4892 19 may may MD cord-022526-j9kg00qf 4892 20 have have VB cord-022526-j9kg00qf 4892 21 a a DT cord-022526-j9kg00qf 4892 22 partial partial JJ cord-022526-j9kg00qf 4892 23 or or CC cord-022526-j9kg00qf 4892 24 functional functional JJ cord-022526-j9kg00qf 4892 25 obstruction obstruction NN cord-022526-j9kg00qf 4892 26 at at IN cord-022526-j9kg00qf 4892 27 an an DT cord-022526-j9kg00qf 4892 28 anastomotic anastomotic JJ cord-022526-j9kg00qf 4892 29 site site NN cord-022526-j9kg00qf 4892 30 . . . cord-022526-j9kg00qf 4893 1 For for IN cord-022526-j9kg00qf 4893 2 example example NN cord-022526-j9kg00qf 4893 3 , , , cord-022526-j9kg00qf 4893 4 in in IN cord-022526-j9kg00qf 4893 5 one one CD cord-022526-j9kg00qf 4893 6 case case NN cord-022526-j9kg00qf 4893 7 report report NN cord-022526-j9kg00qf 4893 8 , , , cord-022526-j9kg00qf 4893 9 a a DT cord-022526-j9kg00qf 4893 10 horse horse NN cord-022526-j9kg00qf 4893 11 developed develop VBD cord-022526-j9kg00qf 4893 12 ileal ileal JJ cord-022526-j9kg00qf 4893 13 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4893 14 after after IN cord-022526-j9kg00qf 4893 15 surgical surgical JJ cord-022526-j9kg00qf 4893 16 correction correction NN cord-022526-j9kg00qf 4893 17 of of IN cord-022526-j9kg00qf 4893 18 an an DT cord-022526-j9kg00qf 4893 19 ileocecal ileocecal JJ cord-022526-j9kg00qf 4893 20 intussusception intussusception NN cord-022526-j9kg00qf 4893 21 . . . cord-022526-j9kg00qf 4894 1 45 45 CD cord-022526-j9kg00qf 4894 2 Ileal Ileal NNP cord-022526-j9kg00qf 4894 3 hypertrophy hypertrophy NN cord-022526-j9kg00qf 4894 4 also also RB cord-022526-j9kg00qf 4894 5 was be VBD cord-022526-j9kg00qf 4894 6 noted note VBN cord-022526-j9kg00qf 4894 7 in in IN cord-022526-j9kg00qf 4894 8 a a DT cord-022526-j9kg00qf 4894 9 horse horse NN cord-022526-j9kg00qf 4894 10 with with IN cord-022526-j9kg00qf 4894 11 cecal cecal JJ cord-022526-j9kg00qf 4894 12 impaction impaction NN cord-022526-j9kg00qf 4894 13 in in IN cord-022526-j9kg00qf 4894 14 which which WDT cord-022526-j9kg00qf 4894 15 an an DT cord-022526-j9kg00qf 4894 16 ileocolic ileocolic JJ cord-022526-j9kg00qf 4894 17 anastomosis anastomosis NN cord-022526-j9kg00qf 4894 18 was be VBD cord-022526-j9kg00qf 4894 19 oriented orient VBN cord-022526-j9kg00qf 4894 20 incorrectly incorrectly RB cord-022526-j9kg00qf 4894 21 . . . cord-022526-j9kg00qf 4895 1 46 46 CD cord-022526-j9kg00qf 4895 2 Horses horse NNS cord-022526-j9kg00qf 4895 3 are be VBP cord-022526-j9kg00qf 4895 4 typically typically RB cord-022526-j9kg00qf 4895 5 re re VBG cord-022526-j9kg00qf 4895 6 - - VBN cord-022526-j9kg00qf 4895 7 presented present VBN cord-022526-j9kg00qf 4895 8 for for IN cord-022526-j9kg00qf 4895 9 recurrence recurrence NN cord-022526-j9kg00qf 4895 10 of of IN cord-022526-j9kg00qf 4895 11 colic colic NN cord-022526-j9kg00qf 4895 12 in in IN cord-022526-j9kg00qf 4895 13 these these DT cord-022526-j9kg00qf 4895 14 cases case NNS cord-022526-j9kg00qf 4895 15 . . . cord-022526-j9kg00qf 4896 1 Surgical surgical JJ cord-022526-j9kg00qf 4896 2 therapy therapy NN cord-022526-j9kg00qf 4896 3 is be VBZ cord-022526-j9kg00qf 4896 4 directed direct VBN cord-022526-j9kg00qf 4896 5 at at IN cord-022526-j9kg00qf 4896 6 addressing address VBG cord-022526-j9kg00qf 4896 7 the the DT cord-022526-j9kg00qf 4896 8 cause cause NN cord-022526-j9kg00qf 4896 9 of of IN cord-022526-j9kg00qf 4896 10 small small JJ cord-022526-j9kg00qf 4896 11 intestinal intestinal JJ cord-022526-j9kg00qf 4896 12 obstruction obstruction NN cord-022526-j9kg00qf 4896 13 and and CC cord-022526-j9kg00qf 4896 14 resecting resect VBG cord-022526-j9kg00qf 4896 15 hypertrophied hypertrophied JJ cord-022526-j9kg00qf 4896 16 intestine intestine NN cord-022526-j9kg00qf 4896 17 . . . cord-022526-j9kg00qf 4897 1 Meckel Meckel NNP cord-022526-j9kg00qf 4897 2 's 's POS cord-022526-j9kg00qf 4897 3 diverticulum diverticulum NN cord-022526-j9kg00qf 4897 4 is be VBZ cord-022526-j9kg00qf 4897 5 an an DT cord-022526-j9kg00qf 4897 6 embryonic embryonic JJ cord-022526-j9kg00qf 4897 7 remnant remnant NN cord-022526-j9kg00qf 4897 8 of of IN cord-022526-j9kg00qf 4897 9 the the DT cord-022526-j9kg00qf 4897 10 vitelloumbilical vitelloumbilical JJ cord-022526-j9kg00qf 4897 11 duct duct NN cord-022526-j9kg00qf 4897 12 , , , cord-022526-j9kg00qf 4897 13 which which WDT cord-022526-j9kg00qf 4897 14 fails fail VBZ cord-022526-j9kg00qf 4897 15 to to TO cord-022526-j9kg00qf 4897 16 atrophy atrophy VB cord-022526-j9kg00qf 4897 17 completely completely RB cord-022526-j9kg00qf 4897 18 and and CC cord-022526-j9kg00qf 4897 19 becomes become VBZ cord-022526-j9kg00qf 4897 20 a a DT cord-022526-j9kg00qf 4897 21 blind blind JJ cord-022526-j9kg00qf 4897 22 pouch pouch NN cord-022526-j9kg00qf 4897 23 projecting project VBG cord-022526-j9kg00qf 4897 24 from from IN cord-022526-j9kg00qf 4897 25 the the DT cord-022526-j9kg00qf 4897 26 antimesenteric antimesenteric JJ cord-022526-j9kg00qf 4897 27 border border NN cord-022526-j9kg00qf 4897 28 of of IN cord-022526-j9kg00qf 4897 29 the the DT cord-022526-j9kg00qf 4897 30 ileum ileum NN cord-022526-j9kg00qf 4897 31 . . . cord-022526-j9kg00qf 4898 1 47 47 CD cord-022526-j9kg00qf 4898 2 , , , cord-022526-j9kg00qf 4898 3 48 48 CD cord-022526-j9kg00qf 4899 1 However however RB cord-022526-j9kg00qf 4899 2 , , , cord-022526-j9kg00qf 4899 3 similar similar JJ cord-022526-j9kg00qf 4899 4 diverticula diverticula NN cord-022526-j9kg00qf 4899 5 also also RB cord-022526-j9kg00qf 4899 6 have have VBP cord-022526-j9kg00qf 4899 7 been be VBN cord-022526-j9kg00qf 4899 8 noted note VBN cord-022526-j9kg00qf 4899 9 in in IN cord-022526-j9kg00qf 4899 10 the the DT cord-022526-j9kg00qf 4899 11 jejunum jejunum NN cord-022526-j9kg00qf 4899 12 . . . cord-022526-j9kg00qf 4900 1 49 49 CD cord-022526-j9kg00qf 4901 1 These these DT cord-022526-j9kg00qf 4901 2 diverticula diverticulum NNS cord-022526-j9kg00qf 4901 3 may may MD cord-022526-j9kg00qf 4901 4 become become VB cord-022526-j9kg00qf 4901 5 impacted impact VBN cord-022526-j9kg00qf 4901 6 , , , cord-022526-j9kg00qf 4901 7 resulting result VBG cord-022526-j9kg00qf 4901 8 in in IN cord-022526-j9kg00qf 4901 9 partial partial JJ cord-022526-j9kg00qf 4901 10 luminal luminal JJ cord-022526-j9kg00qf 4901 11 obstruction obstruction NN cord-022526-j9kg00qf 4901 12 , , , cord-022526-j9kg00qf 4901 13 or or CC cord-022526-j9kg00qf 4901 14 may may MD cord-022526-j9kg00qf 4901 15 wrap wrap VB cord-022526-j9kg00qf 4901 16 around around RP cord-022526-j9kg00qf 4901 17 an an DT cord-022526-j9kg00qf 4901 18 adjacent adjacent JJ cord-022526-j9kg00qf 4901 19 segment segment NN cord-022526-j9kg00qf 4901 20 of of IN cord-022526-j9kg00qf 4901 21 intestine intestine NN cord-022526-j9kg00qf 4901 22 , , , cord-022526-j9kg00qf 4901 23 causing cause VBG cord-022526-j9kg00qf 4901 24 strangulation strangulation NN cord-022526-j9kg00qf 4901 25 . . . cord-022526-j9kg00qf 4902 1 47 47 CD cord-022526-j9kg00qf 4902 2 Occasionally occasionally RB cord-022526-j9kg00qf 4902 3 , , , cord-022526-j9kg00qf 4902 4 an an DT cord-022526-j9kg00qf 4902 5 associated associate VBN cord-022526-j9kg00qf 4902 6 mesodiverticular mesodiverticular NNP cord-022526-j9kg00qf 4902 7 band band NN cord-022526-j9kg00qf 4902 8 may may MD cord-022526-j9kg00qf 4902 9 course course RB cord-022526-j9kg00qf 4902 10 from from IN cord-022526-j9kg00qf 4902 11 the the DT cord-022526-j9kg00qf 4902 12 diverticulum diverticulum NN cord-022526-j9kg00qf 4902 13 to to IN cord-022526-j9kg00qf 4902 14 the the DT cord-022526-j9kg00qf 4902 15 umbilical umbilical JJ cord-022526-j9kg00qf 4902 16 remnant remnant NN cord-022526-j9kg00qf 4902 17 and and CC cord-022526-j9kg00qf 4902 18 serve serve VB cord-022526-j9kg00qf 4902 19 as as IN cord-022526-j9kg00qf 4902 20 a a DT cord-022526-j9kg00qf 4902 21 point point NN cord-022526-j9kg00qf 4902 22 around around IN cord-022526-j9kg00qf 4902 23 which which WDT cord-022526-j9kg00qf 4902 24 small small JJ cord-022526-j9kg00qf 4902 25 intestine intestine NN cord-022526-j9kg00qf 4902 26 may may MD cord-022526-j9kg00qf 4902 27 become become VB cord-022526-j9kg00qf 4902 28 strangulated strangulate VBN cord-022526-j9kg00qf 4902 29 . . . cord-022526-j9kg00qf 4903 1 Mesodiverticular Mesodiverticular NNP cord-022526-j9kg00qf 4903 2 bands band NNS cord-022526-j9kg00qf 4903 3 also also RB cord-022526-j9kg00qf 4903 4 may may MD cord-022526-j9kg00qf 4903 5 originate originate VB cord-022526-j9kg00qf 4903 6 from from IN cord-022526-j9kg00qf 4903 7 the the DT cord-022526-j9kg00qf 4903 8 embryonic embryonic JJ cord-022526-j9kg00qf 4903 9 ventral ventral JJ cord-022526-j9kg00qf 4903 10 mesentery mesentery NN cord-022526-j9kg00qf 4903 11 and and CC cord-022526-j9kg00qf 4903 12 attach attach VB cord-022526-j9kg00qf 4903 13 to to IN cord-022526-j9kg00qf 4903 14 the the DT cord-022526-j9kg00qf 4903 15 antimesenteric antimesenteric JJ cord-022526-j9kg00qf 4903 16 surface surface NN cord-022526-j9kg00qf 4903 17 of of IN cord-022526-j9kg00qf 4903 18 the the DT cord-022526-j9kg00qf 4903 19 bowel bowel NN cord-022526-j9kg00qf 4903 20 , , , cord-022526-j9kg00qf 4903 21 thereby thereby RB cord-022526-j9kg00qf 4903 22 forming form VBG cord-022526-j9kg00qf 4903 23 a a DT cord-022526-j9kg00qf 4903 24 potential potential JJ cord-022526-j9kg00qf 4903 25 space space NN cord-022526-j9kg00qf 4903 26 within within IN cord-022526-j9kg00qf 4903 27 which which WDT cord-022526-j9kg00qf 4903 28 intestine intestine NN cord-022526-j9kg00qf 4903 29 may may MD cord-022526-j9kg00qf 4903 30 become become VB cord-022526-j9kg00qf 4903 31 entrapped entrap VBN cord-022526-j9kg00qf 4903 32 . . . cord-022526-j9kg00qf 4904 1 Clinical clinical JJ cord-022526-j9kg00qf 4904 2 signs sign NNS cord-022526-j9kg00qf 4904 3 range range VBP cord-022526-j9kg00qf 4904 4 from from IN cord-022526-j9kg00qf 4904 5 chronic chronic JJ cord-022526-j9kg00qf 4904 6 colic colic NN cord-022526-j9kg00qf 4904 7 for for IN cord-022526-j9kg00qf 4904 8 an an DT cord-022526-j9kg00qf 4904 9 impacted impact VBN cord-022526-j9kg00qf 4904 10 Meckel Meckel NNP cord-022526-j9kg00qf 4904 11 's 's POS cord-022526-j9kg00qf 4904 12 diverticulum diverticulum NN cord-022526-j9kg00qf 4904 13 to to IN cord-022526-j9kg00qf 4904 14 acute acute JJ cord-022526-j9kg00qf 4904 15 severe severe JJ cord-022526-j9kg00qf 4904 16 colic colic NN cord-022526-j9kg00qf 4904 17 for for IN cord-022526-j9kg00qf 4904 18 intestine intestine NN cord-022526-j9kg00qf 4904 19 strangulated strangulate VBN cord-022526-j9kg00qf 4904 20 by by IN cord-022526-j9kg00qf 4904 21 a a DT cord-022526-j9kg00qf 4904 22 mesodiverticular mesodiverticular JJ cord-022526-j9kg00qf 4904 23 band band NN cord-022526-j9kg00qf 4904 24 . . . cord-022526-j9kg00qf 4905 1 One one PRP cord-022526-j9kg00qf 4905 2 makes make VBZ cord-022526-j9kg00qf 4905 3 the the DT cord-022526-j9kg00qf 4905 4 diagnosis diagnosis NN cord-022526-j9kg00qf 4905 5 at at IN cord-022526-j9kg00qf 4905 6 surgery surgery NN cord-022526-j9kg00qf 4905 7 , , , cord-022526-j9kg00qf 4905 8 and and CC cord-022526-j9kg00qf 4905 9 treatment treatment NN cord-022526-j9kg00qf 4905 10 requires require VBZ cord-022526-j9kg00qf 4905 11 resection resection NN cord-022526-j9kg00qf 4905 12 of of IN cord-022526-j9kg00qf 4905 13 the the DT cord-022526-j9kg00qf 4905 14 diverticulum diverticulum NN cord-022526-j9kg00qf 4905 15 and and CC cord-022526-j9kg00qf 4905 16 any any DT cord-022526-j9kg00qf 4905 17 associated associated JJ cord-022526-j9kg00qf 4905 18 bands band NNS cord-022526-j9kg00qf 4905 19 . . . cord-022526-j9kg00qf 4906 1 The the DT cord-022526-j9kg00qf 4906 2 prognosis prognosis NN cord-022526-j9kg00qf 4906 3 is be VBZ cord-022526-j9kg00qf 4906 4 good good JJ cord-022526-j9kg00qf 4906 5 for for IN cord-022526-j9kg00qf 4906 6 horses horse NNS cord-022526-j9kg00qf 4906 7 with with IN cord-022526-j9kg00qf 4906 8 simple simple JJ cord-022526-j9kg00qf 4906 9 impaction impaction NN cord-022526-j9kg00qf 4906 10 of of IN cord-022526-j9kg00qf 4906 11 a a DT cord-022526-j9kg00qf 4906 12 Meckel Meckel NNP cord-022526-j9kg00qf 4906 13 's 's POS cord-022526-j9kg00qf 4906 14 diverticulum diverticulum NN cord-022526-j9kg00qf 4906 15 and and CC cord-022526-j9kg00qf 4906 16 is be VBZ cord-022526-j9kg00qf 4906 17 guarded guard VBN cord-022526-j9kg00qf 4906 18 for for IN cord-022526-j9kg00qf 4906 19 horses horse NNS cord-022526-j9kg00qf 4906 20 with with IN cord-022526-j9kg00qf 4906 21 an an DT cord-022526-j9kg00qf 4906 22 associated associated JJ cord-022526-j9kg00qf 4906 23 small small JJ cord-022526-j9kg00qf 4906 24 intestinal intestinal JJ cord-022526-j9kg00qf 4906 25 strangulation strangulation NN cord-022526-j9kg00qf 4906 26 . . . cord-022526-j9kg00qf 4907 1 50 50 CD cord-022526-j9kg00qf 4907 2 Adhesions adhesion NNS cord-022526-j9kg00qf 4907 3 of of IN cord-022526-j9kg00qf 4907 4 one one CD cord-022526-j9kg00qf 4907 5 segment segment NN cord-022526-j9kg00qf 4907 6 of of IN cord-022526-j9kg00qf 4907 7 bowel bowel NN cord-022526-j9kg00qf 4907 8 to to IN cord-022526-j9kg00qf 4907 9 another another DT cord-022526-j9kg00qf 4907 10 or or CC cord-022526-j9kg00qf 4907 11 of of IN cord-022526-j9kg00qf 4907 12 a a DT cord-022526-j9kg00qf 4907 13 segment segment NN cord-022526-j9kg00qf 4907 14 of of IN cord-022526-j9kg00qf 4907 15 intestine intestine NN cord-022526-j9kg00qf 4907 16 to to IN cord-022526-j9kg00qf 4907 17 other other JJ cord-022526-j9kg00qf 4907 18 organs organ NNS cord-022526-j9kg00qf 4907 19 and and CC cord-022526-j9kg00qf 4907 20 the the DT cord-022526-j9kg00qf 4907 21 body body NN cord-022526-j9kg00qf 4907 22 wall wall NN cord-022526-j9kg00qf 4907 23 most most RBS cord-022526-j9kg00qf 4907 24 typically typically RB cord-022526-j9kg00qf 4907 25 occur occur VBP cord-022526-j9kg00qf 4907 26 following follow VBG cord-022526-j9kg00qf 4907 27 abdominal abdominal JJ cord-022526-j9kg00qf 4907 28 surgery surgery NN cord-022526-j9kg00qf 4907 29 and and CC cord-022526-j9kg00qf 4907 30 may may MD cord-022526-j9kg00qf 4907 31 be be VB cord-022526-j9kg00qf 4907 32 clinically clinically RB cord-022526-j9kg00qf 4907 33 silent silent JJ cord-022526-j9kg00qf 4907 34 , , , cord-022526-j9kg00qf 4907 35 cause cause VBP cord-022526-j9kg00qf 4907 36 chronic chronic JJ cord-022526-j9kg00qf 4907 37 colic colic NN cord-022526-j9kg00qf 4907 38 attributable attributable JJ cord-022526-j9kg00qf 4907 39 to to IN cord-022526-j9kg00qf 4907 40 partial partial JJ cord-022526-j9kg00qf 4907 41 obstruction obstruction NN cord-022526-j9kg00qf 4907 42 , , , cord-022526-j9kg00qf 4907 43 or or CC cord-022526-j9kg00qf 4907 44 result result VB cord-022526-j9kg00qf 4907 45 in in IN cord-022526-j9kg00qf 4907 46 acute acute JJ cord-022526-j9kg00qf 4907 47 obstruction obstruction NN cord-022526-j9kg00qf 4907 48 . . . cord-022526-j9kg00qf 4908 1 These these DT cord-022526-j9kg00qf 4908 2 differing differ VBG cord-022526-j9kg00qf 4908 3 clinical clinical JJ cord-022526-j9kg00qf 4908 4 syndromes syndrome NNS cord-022526-j9kg00qf 4908 5 are be VBP cord-022526-j9kg00qf 4908 6 attributable attributable JJ cord-022526-j9kg00qf 4908 7 to to IN cord-022526-j9kg00qf 4908 8 the the DT cord-022526-j9kg00qf 4908 9 type type NN cord-022526-j9kg00qf 4908 10 of of IN cord-022526-j9kg00qf 4908 11 adhesions adhesion NNS cord-022526-j9kg00qf 4908 12 that that WDT cord-022526-j9kg00qf 4908 13 develop develop VBP cord-022526-j9kg00qf 4908 14 . . . cord-022526-j9kg00qf 4909 1 For for IN cord-022526-j9kg00qf 4909 2 example example NN cord-022526-j9kg00qf 4909 3 , , , cord-022526-j9kg00qf 4909 4 a a DT cord-022526-j9kg00qf 4909 5 fibrous fibrous JJ cord-022526-j9kg00qf 4909 6 adhesion adhesion NN cord-022526-j9kg00qf 4909 7 that that WDT cord-022526-j9kg00qf 4909 8 does do VBZ cord-022526-j9kg00qf 4909 9 not not RB cord-022526-j9kg00qf 4909 10 by by IN cord-022526-j9kg00qf 4909 11 itself -PRON- PRP cord-022526-j9kg00qf 4909 12 obstruct obstruct VB cord-022526-j9kg00qf 4909 13 the the DT cord-022526-j9kg00qf 4909 14 intestinal intestinal JJ cord-022526-j9kg00qf 4909 15 lumen lumen NN cord-022526-j9kg00qf 4909 16 might may MD cord-022526-j9kg00qf 4909 17 serve serve VB cord-022526-j9kg00qf 4909 18 as as IN cord-022526-j9kg00qf 4909 19 the the DT cord-022526-j9kg00qf 4909 20 pivot pivot NN cord-022526-j9kg00qf 4909 21 point point NN cord-022526-j9kg00qf 4909 22 for for IN cord-022526-j9kg00qf 4909 23 a a DT cord-022526-j9kg00qf 4909 24 volvulus volvulus NN cord-022526-j9kg00qf 4909 25 , , , cord-022526-j9kg00qf 4909 26 whereas whereas IN cord-022526-j9kg00qf 4909 27 an an DT cord-022526-j9kg00qf 4909 28 adhesion adhesion NN cord-022526-j9kg00qf 4909 29 between between IN cord-022526-j9kg00qf 4909 30 adjacent adjacent JJ cord-022526-j9kg00qf 4909 31 segments segment NNS cord-022526-j9kg00qf 4909 32 of of IN cord-022526-j9kg00qf 4909 33 the the DT cord-022526-j9kg00qf 4909 34 intestinal intestinal JJ cord-022526-j9kg00qf 4909 35 tract tract NN cord-022526-j9kg00qf 4909 36 may may MD cord-022526-j9kg00qf 4909 37 create create VB cord-022526-j9kg00qf 4909 38 a a DT cord-022526-j9kg00qf 4909 39 hairpin hairpin NN cord-022526-j9kg00qf 4909 40 turn turn NN cord-022526-j9kg00qf 4909 41 that that WDT cord-022526-j9kg00qf 4909 42 causes cause VBZ cord-022526-j9kg00qf 4909 43 chronic chronic JJ cord-022526-j9kg00qf 4909 44 partial partial JJ cord-022526-j9kg00qf 4909 45 obstruction obstruction NN cord-022526-j9kg00qf 4909 46 . . . cord-022526-j9kg00qf 4910 1 51 51 CD cord-022526-j9kg00qf 4911 1 The the DT cord-022526-j9kg00qf 4911 2 number number NN cord-022526-j9kg00qf 4911 3 of of IN cord-022526-j9kg00qf 4911 4 adhesions adhesion NNS cord-022526-j9kg00qf 4911 5 that that WDT cord-022526-j9kg00qf 4911 6 develop develop VBP cord-022526-j9kg00qf 4911 7 also also RB cord-022526-j9kg00qf 4911 8 may may MD cord-022526-j9kg00qf 4911 9 vary vary VB cord-022526-j9kg00qf 4911 10 greatly greatly RB cord-022526-j9kg00qf 4911 11 from from IN cord-022526-j9kg00qf 4911 12 horse horse NN cord-022526-j9kg00qf 4911 13 to to IN cord-022526-j9kg00qf 4911 14 horse horse NN cord-022526-j9kg00qf 4911 15 . . . cord-022526-j9kg00qf 4912 1 Some some DT cord-022526-j9kg00qf 4912 2 horses horse NNS cord-022526-j9kg00qf 4912 3 may may MD cord-022526-j9kg00qf 4912 4 develop develop VB cord-022526-j9kg00qf 4912 5 a a DT cord-022526-j9kg00qf 4912 6 single single JJ cord-022526-j9kg00qf 4912 7 adhesion adhesion NN cord-022526-j9kg00qf 4912 8 adjacent adjacent JJ cord-022526-j9kg00qf 4912 9 to to IN cord-022526-j9kg00qf 4912 10 an an DT cord-022526-j9kg00qf 4912 11 anastomotic anastomotic JJ cord-022526-j9kg00qf 4912 12 site site NN cord-022526-j9kg00qf 4912 13 or or CC cord-022526-j9kg00qf 4912 14 a a DT cord-022526-j9kg00qf 4912 15 discrete discrete JJ cord-022526-j9kg00qf 4912 16 segment segment NN cord-022526-j9kg00qf 4912 17 of of IN cord-022526-j9kg00qf 4912 18 injured injured JJ cord-022526-j9kg00qf 4912 19 intestine intestine NN cord-022526-j9kg00qf 4912 20 , , , cord-022526-j9kg00qf 4912 21 whereas whereas IN cord-022526-j9kg00qf 4912 22 other other JJ cord-022526-j9kg00qf 4912 23 horses horse NNS cord-022526-j9kg00qf 4912 24 may may MD cord-022526-j9kg00qf 4912 25 develop develop VB cord-022526-j9kg00qf 4912 26 diffuse diffuse JJ cord-022526-j9kg00qf 4912 27 adhesions adhesion NNS cord-022526-j9kg00qf 4912 28 involving involve VBG cord-022526-j9kg00qf 4912 29 multiple multiple JJ cord-022526-j9kg00qf 4912 30 segments segment NNS cord-022526-j9kg00qf 4912 31 of of IN cord-022526-j9kg00qf 4912 32 intestine intestine NN cord-022526-j9kg00qf 4912 33 , , , cord-022526-j9kg00qf 4912 34 likely likely JJ cord-022526-j9kg00qf 4912 35 because because IN cord-022526-j9kg00qf 4912 36 of of IN cord-022526-j9kg00qf 4912 37 widespread widespread JJ cord-022526-j9kg00qf 4912 38 inflammation inflammation NN cord-022526-j9kg00qf 4912 39 of of IN cord-022526-j9kg00qf 4912 40 the the DT cord-022526-j9kg00qf 4912 41 peritoneum peritoneum NN cord-022526-j9kg00qf 4912 42 at at IN cord-022526-j9kg00qf 4912 43 the the DT cord-022526-j9kg00qf 4912 44 time time NN cord-022526-j9kg00qf 4912 45 of of IN cord-022526-j9kg00qf 4912 46 the the DT cord-022526-j9kg00qf 4912 47 original original JJ cord-022526-j9kg00qf 4912 48 surgery surgery NN cord-022526-j9kg00qf 4912 49 . . . cord-022526-j9kg00qf 4913 1 The the DT cord-022526-j9kg00qf 4913 2 mechanism mechanism NN cord-022526-j9kg00qf 4913 3 whereby whereby WRB cord-022526-j9kg00qf 4913 4 adhesions adhesion NNS cord-022526-j9kg00qf 4913 5 develop develop VBP cord-022526-j9kg00qf 4913 6 is be VBZ cord-022526-j9kg00qf 4913 7 complex complex JJ cord-022526-j9kg00qf 4913 8 but but CC cord-022526-j9kg00qf 4913 9 likely likely JJ cord-022526-j9kg00qf 4913 10 involves involve VBZ cord-022526-j9kg00qf 4913 11 initial initial JJ cord-022526-j9kg00qf 4913 12 injury injury NN cord-022526-j9kg00qf 4913 13 to to IN cord-022526-j9kg00qf 4913 14 the the DT cord-022526-j9kg00qf 4913 15 serosa serosa NNP cord-022526-j9kg00qf 4913 16 initiated initiate VBN cord-022526-j9kg00qf 4913 17 by by IN cord-022526-j9kg00qf 4913 18 intestinal intestinal JJ cord-022526-j9kg00qf 4913 19 ischemia ischemia NN cord-022526-j9kg00qf 4913 20 , , , cord-022526-j9kg00qf 4913 21 reperfusion reperfusion NN cord-022526-j9kg00qf 4913 22 injury injury NN cord-022526-j9kg00qf 4913 23 , , , cord-022526-j9kg00qf 4913 24 and and CC cord-022526-j9kg00qf 4913 25 luminal luminal JJ cord-022526-j9kg00qf 4913 26 distention distention NN cord-022526-j9kg00qf 4913 27 . . . cord-022526-j9kg00qf 4914 1 52 52 CD cord-022526-j9kg00qf 4915 1 Importantly importantly RB cord-022526-j9kg00qf 4915 2 , , , cord-022526-j9kg00qf 4915 3 such such JJ cord-022526-j9kg00qf 4915 4 injury injury NN cord-022526-j9kg00qf 4915 5 involves involve VBZ cord-022526-j9kg00qf 4915 6 infiltration infiltration NN cord-022526-j9kg00qf 4915 7 of of IN cord-022526-j9kg00qf 4915 8 neutrophils neutrophil NNS cord-022526-j9kg00qf 4915 9 into into IN cord-022526-j9kg00qf 4915 10 the the DT cord-022526-j9kg00qf 4915 11 serosa serosa NNP cord-022526-j9kg00qf 4915 12 accompanied accompany VBN cord-022526-j9kg00qf 4915 13 by by IN cord-022526-j9kg00qf 4915 14 loss loss NN cord-022526-j9kg00qf 4915 15 of of IN cord-022526-j9kg00qf 4915 16 mesothelial mesothelial JJ cord-022526-j9kg00qf 4915 17 cells cell NNS cord-022526-j9kg00qf 4915 18 . . . cord-022526-j9kg00qf 4916 1 In in IN cord-022526-j9kg00qf 4916 2 one one CD cord-022526-j9kg00qf 4916 3 study study NN cord-022526-j9kg00qf 4916 4 assessing assess VBG cord-022526-j9kg00qf 4916 5 the the DT cord-022526-j9kg00qf 4916 6 margins margin NNS cord-022526-j9kg00qf 4916 7 of of IN cord-022526-j9kg00qf 4916 8 resected resect VBN cord-022526-j9kg00qf 4916 9 small small JJ cord-022526-j9kg00qf 4916 10 intestine intestine NN cord-022526-j9kg00qf 4916 11 , , , cord-022526-j9kg00qf 4916 12 extensive extensive JJ cord-022526-j9kg00qf 4916 13 neutrophil neutrophil NN cord-022526-j9kg00qf 4916 14 infiltration infiltration NN cord-022526-j9kg00qf 4916 15 was be VBD cord-022526-j9kg00qf 4916 16 documented document VBN cord-022526-j9kg00qf 4916 17 in in IN cord-022526-j9kg00qf 4916 18 the the DT cord-022526-j9kg00qf 4916 19 serosa serosa NN cord-022526-j9kg00qf 4916 20 , , , cord-022526-j9kg00qf 4916 21 particularly particularly RB cord-022526-j9kg00qf 4916 22 in in IN cord-022526-j9kg00qf 4916 23 the the DT cord-022526-j9kg00qf 4916 24 proximal proximal JJ cord-022526-j9kg00qf 4916 25 resection resection NN cord-022526-j9kg00qf 4916 26 margin margin NN cord-022526-j9kg00qf 4916 27 that that WDT cord-022526-j9kg00qf 4916 28 had have VBD cord-022526-j9kg00qf 4916 29 been be VBN cord-022526-j9kg00qf 4916 30 distended distend VBN cord-022526-j9kg00qf 4916 31 before before IN cord-022526-j9kg00qf 4916 32 correction correction NN cord-022526-j9kg00qf 4916 33 of of IN cord-022526-j9kg00qf 4916 34 a a DT cord-022526-j9kg00qf 4916 35 variety variety NN cord-022526-j9kg00qf 4916 36 of of IN cord-022526-j9kg00qf 4916 37 strangulating strangulating JJ cord-022526-j9kg00qf 4916 38 lesions lesion NNS cord-022526-j9kg00qf 4916 39 . . . cord-022526-j9kg00qf 4917 1 53 53 CD cord-022526-j9kg00qf 4917 2 Regions region NNS cord-022526-j9kg00qf 4917 3 of of IN cord-022526-j9kg00qf 4917 4 serosal serosal NN cord-022526-j9kg00qf 4917 5 injury injury NN cord-022526-j9kg00qf 4917 6 and and CC cord-022526-j9kg00qf 4917 7 inflammation inflammation NN cord-022526-j9kg00qf 4917 8 subsequently subsequently RB cord-022526-j9kg00qf 4917 9 undergo undergo VBP cord-022526-j9kg00qf 4917 10 reparative reparative JJ cord-022526-j9kg00qf 4917 11 events event NNS cord-022526-j9kg00qf 4917 12 similar similar JJ cord-022526-j9kg00qf 4917 13 to to IN cord-022526-j9kg00qf 4917 14 any any DT cord-022526-j9kg00qf 4917 15 wound wound NN cord-022526-j9kg00qf 4917 16 , , , cord-022526-j9kg00qf 4917 17 including include VBG cord-022526-j9kg00qf 4917 18 local local JJ cord-022526-j9kg00qf 4917 19 production production NN cord-022526-j9kg00qf 4917 20 of of IN cord-022526-j9kg00qf 4917 21 fibrin fibrin NN cord-022526-j9kg00qf 4917 22 , , , cord-022526-j9kg00qf 4917 23 de de FW cord-022526-j9kg00qf 4917 24 novo novo NNP cord-022526-j9kg00qf 4917 25 synthesis synthesis NN cord-022526-j9kg00qf 4917 26 of of IN cord-022526-j9kg00qf 4917 27 collagen collagen NN cord-022526-j9kg00qf 4917 28 by by IN cord-022526-j9kg00qf 4917 29 infiltrating infiltrate VBG cord-022526-j9kg00qf 4917 30 fibroblasts fibroblast NNS cord-022526-j9kg00qf 4917 31 , , , cord-022526-j9kg00qf 4917 32 and and CC cord-022526-j9kg00qf 4917 33 ultimately ultimately RB cord-022526-j9kg00qf 4917 34 maturation maturation NN cord-022526-j9kg00qf 4917 35 and and CC cord-022526-j9kg00qf 4917 36 remodeling remodeling NN cord-022526-j9kg00qf 4917 37 of of IN cord-022526-j9kg00qf 4917 38 fibrous fibrous JJ cord-022526-j9kg00qf 4917 39 tissue tissue NN cord-022526-j9kg00qf 4917 40 . . . cord-022526-j9kg00qf 4918 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 4918 2 , , , cord-022526-j9kg00qf 4918 3 during during IN cord-022526-j9kg00qf 4918 4 this this DT cord-022526-j9kg00qf 4918 5 process process NN cord-022526-j9kg00qf 4918 6 , , , cord-022526-j9kg00qf 4918 7 fibrin fibrin NN cord-022526-j9kg00qf 4918 8 may may MD cord-022526-j9kg00qf 4918 9 result result VB cord-022526-j9kg00qf 4918 10 in in IN cord-022526-j9kg00qf 4918 11 injured injured JJ cord-022526-j9kg00qf 4918 12 intestinal intestinal JJ cord-022526-j9kg00qf 4918 13 surfaces surface NNS cord-022526-j9kg00qf 4918 14 adhering adhere VBG cord-022526-j9kg00qf 4918 15 to to IN cord-022526-j9kg00qf 4918 16 adjacent adjacent JJ cord-022526-j9kg00qf 4918 17 injured injured JJ cord-022526-j9kg00qf 4918 18 bowel bowel NN cord-022526-j9kg00qf 4918 19 or or CC cord-022526-j9kg00qf 4918 20 an an DT cord-022526-j9kg00qf 4918 21 adjacent adjacent JJ cord-022526-j9kg00qf 4918 22 organ organ NN cord-022526-j9kg00qf 4918 23 . . . cord-022526-j9kg00qf 4919 1 Once once IN cord-022526-j9kg00qf 4919 2 a a DT cord-022526-j9kg00qf 4919 3 fibrinous fibrinous JJ cord-022526-j9kg00qf 4919 4 adhesion adhesion NN cord-022526-j9kg00qf 4919 5 has have VBZ cord-022526-j9kg00qf 4919 6 developed develop VBN cord-022526-j9kg00qf 4919 7 , , , cord-022526-j9kg00qf 4919 8 new new JJ cord-022526-j9kg00qf 4919 9 collagen collagen NN cord-022526-j9kg00qf 4919 10 synthesis synthesis NN cord-022526-j9kg00qf 4919 11 may may MD cord-022526-j9kg00qf 4919 12 result result VB cord-022526-j9kg00qf 4919 13 in in IN cord-022526-j9kg00qf 4919 14 a a DT cord-022526-j9kg00qf 4919 15 permanent permanent JJ cord-022526-j9kg00qf 4919 16 fibrous fibrous JJ cord-022526-j9kg00qf 4919 17 adhesion adhesion NN cord-022526-j9kg00qf 4919 18 . . . cord-022526-j9kg00qf 4920 1 Alternatively alternatively RB cord-022526-j9kg00qf 4920 2 , , , cord-022526-j9kg00qf 4920 3 proteases protease NNS cord-022526-j9kg00qf 4920 4 released release VBN cord-022526-j9kg00qf 4920 5 by by IN cord-022526-j9kg00qf 4920 6 local local JJ cord-022526-j9kg00qf 4920 7 phagocytes phagocyte NNS cord-022526-j9kg00qf 4920 8 may may MD cord-022526-j9kg00qf 4920 9 lyse lyse VB cord-022526-j9kg00qf 4920 10 fibrinous fibrinous NNP cord-022526-j9kg00qf 4920 11 exudate exudate NNP cord-022526-j9kg00qf 4920 12 , , , cord-022526-j9kg00qf 4920 13 thereby thereby RB cord-022526-j9kg00qf 4920 14 reversing reverse VBG cord-022526-j9kg00qf 4920 15 the the DT cord-022526-j9kg00qf 4920 16 adhesive adhesive JJ cord-022526-j9kg00qf 4920 17 process process NN cord-022526-j9kg00qf 4920 18 . . . cord-022526-j9kg00qf 4921 1 Thus thus RB cord-022526-j9kg00qf 4921 2 one one PRP cord-022526-j9kg00qf 4921 3 can can MD cord-022526-j9kg00qf 4921 4 view view VB cord-022526-j9kg00qf 4921 5 formation formation NN cord-022526-j9kg00qf 4921 6 of of IN cord-022526-j9kg00qf 4921 7 adhesions adhesion NNS cord-022526-j9kg00qf 4921 8 as as IN cord-022526-j9kg00qf 4921 9 an an DT cord-022526-j9kg00qf 4921 10 imbalance imbalance NN cord-022526-j9kg00qf 4921 11 of of IN cord-022526-j9kg00qf 4921 12 fibrin fibrin NN cord-022526-j9kg00qf 4921 13 deposition deposition NN cord-022526-j9kg00qf 4921 14 and and CC cord-022526-j9kg00qf 4921 15 fibrinolysis fibrinolysis NN cord-022526-j9kg00qf 4921 16 . . . cord-022526-j9kg00qf 4922 1 54 54 CD cord-022526-j9kg00qf 4922 2 Prevention prevention NN cord-022526-j9kg00qf 4922 3 of of IN cord-022526-j9kg00qf 4922 4 adhesions adhesion NNS cord-022526-j9kg00qf 4922 5 depends depend VBZ cord-022526-j9kg00qf 4922 6 on on IN cord-022526-j9kg00qf 4922 7 inhibition inhibition NN cord-022526-j9kg00qf 4922 8 of of IN cord-022526-j9kg00qf 4922 9 the the DT cord-022526-j9kg00qf 4922 10 mechanisms mechanism NNS cord-022526-j9kg00qf 4922 11 involved involve VBN cord-022526-j9kg00qf 4922 12 in in IN cord-022526-j9kg00qf 4922 13 adhesion adhesion NN cord-022526-j9kg00qf 4922 14 formation formation NN cord-022526-j9kg00qf 4922 15 , , , cord-022526-j9kg00qf 4922 16 including include VBG cord-022526-j9kg00qf 4922 17 reduction reduction NN cord-022526-j9kg00qf 4922 18 of of IN cord-022526-j9kg00qf 4922 19 serosal serosal NN cord-022526-j9kg00qf 4922 20 injury injury NN cord-022526-j9kg00qf 4922 21 with with IN cord-022526-j9kg00qf 4922 22 early early JJ cord-022526-j9kg00qf 4922 23 intervention intervention NN cord-022526-j9kg00qf 4922 24 and and CC cord-022526-j9kg00qf 4922 25 good good JJ cord-022526-j9kg00qf 4922 26 surgical surgical JJ cord-022526-j9kg00qf 4922 27 technique technique NN cord-022526-j9kg00qf 4922 28 , , , cord-022526-j9kg00qf 4922 29 reduction reduction NN cord-022526-j9kg00qf 4922 30 of of IN cord-022526-j9kg00qf 4922 31 inflammation inflammation NN cord-022526-j9kg00qf 4922 32 by by IN cord-022526-j9kg00qf 4922 33 administration administration NN cord-022526-j9kg00qf 4922 34 of of IN cord-022526-j9kg00qf 4922 35 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 4922 36 medications medication NNS cord-022526-j9kg00qf 4922 37 , , , cord-022526-j9kg00qf 4922 38 physical physical JJ cord-022526-j9kg00qf 4922 39 separation separation NN cord-022526-j9kg00qf 4922 40 of of IN cord-022526-j9kg00qf 4922 41 inflamed inflamed JJ cord-022526-j9kg00qf 4922 42 serosal serosal NN cord-022526-j9kg00qf 4922 43 surfaces surface NNS cord-022526-j9kg00qf 4922 44 ( ( -LRB- cord-022526-j9kg00qf 4922 45 e.g. e.g. RB cord-022526-j9kg00qf 4922 46 , , , cord-022526-j9kg00qf 4922 47 carboxymethylcellulose carboxymethylcellulose NNP cord-022526-j9kg00qf 4922 48 and and CC cord-022526-j9kg00qf 4922 49 hyaluronan hyaluronan NNP cord-022526-j9kg00qf 4922 50 ) ) -RRB- cord-022526-j9kg00qf 4922 51 , , , cord-022526-j9kg00qf 4922 52 [ [ -LRB- cord-022526-j9kg00qf 4922 53 55 55 CD cord-022526-j9kg00qf 4922 54 ] ] -RRB- cord-022526-j9kg00qf 4923 1 [ [ -LRB- cord-022526-j9kg00qf 4923 2 56 56 CD cord-022526-j9kg00qf 4923 3 ] ] -RRB- cord-022526-j9kg00qf 4923 4 [ [ -LRB- cord-022526-j9kg00qf 4923 5 57 57 CD cord-022526-j9kg00qf 4923 6 ] ] -RRB- cord-022526-j9kg00qf 4923 7 and and CC cord-022526-j9kg00qf 4923 8 pharmacologic pharmacologic JJ cord-022526-j9kg00qf 4923 9 modulation modulation NN cord-022526-j9kg00qf 4923 10 of of IN cord-022526-j9kg00qf 4923 11 fibrinous fibrinous JJ cord-022526-j9kg00qf 4923 12 adhesion adhesion NN cord-022526-j9kg00qf 4923 13 formation formation NN cord-022526-j9kg00qf 4923 14 ( ( -LRB- cord-022526-j9kg00qf 4923 15 e.g. e.g. RB cord-022526-j9kg00qf 4923 16 , , , cord-022526-j9kg00qf 4923 17 heparin heparin NN cord-022526-j9kg00qf 4923 18 ) ) -RRB- cord-022526-j9kg00qf 4923 19 . . . cord-022526-j9kg00qf 4924 1 58 58 CD cord-022526-j9kg00qf 4925 1 In in IN cord-022526-j9kg00qf 4925 2 addition addition NN cord-022526-j9kg00qf 4925 3 , , , cord-022526-j9kg00qf 4925 4 early early JJ cord-022526-j9kg00qf 4925 5 return return NN cord-022526-j9kg00qf 4925 6 of of IN cord-022526-j9kg00qf 4925 7 motility motility NN cord-022526-j9kg00qf 4925 8 in in IN cord-022526-j9kg00qf 4925 9 the the DT cord-022526-j9kg00qf 4925 10 small small JJ cord-022526-j9kg00qf 4925 11 intestine intestine NN cord-022526-j9kg00qf 4925 12 after after IN cord-022526-j9kg00qf 4925 13 surgery surgery NN cord-022526-j9kg00qf 4925 14 may may MD cord-022526-j9kg00qf 4925 15 reduce reduce VB cord-022526-j9kg00qf 4925 16 contact contact NN cord-022526-j9kg00qf 4925 17 time time NN cord-022526-j9kg00qf 4925 18 between between IN cord-022526-j9kg00qf 4925 19 inflamed inflamed JJ cord-022526-j9kg00qf 4925 20 surfaces surface NNS cord-022526-j9kg00qf 4925 21 of of IN cord-022526-j9kg00qf 4925 22 intestine intestine NN cord-022526-j9kg00qf 4925 23 , , , cord-022526-j9kg00qf 4925 24 thereby thereby RB cord-022526-j9kg00qf 4925 25 reducing reduce VBG cord-022526-j9kg00qf 4925 26 the the DT cord-022526-j9kg00qf 4925 27 chances chance NNS cord-022526-j9kg00qf 4925 28 of of IN cord-022526-j9kg00qf 4925 29 adhesion adhesion NN cord-022526-j9kg00qf 4925 30 formation formation NN cord-022526-j9kg00qf 4925 31 . . . cord-022526-j9kg00qf 4926 1 54 54 CD cord-022526-j9kg00qf 4926 2 Horses horse NNS cord-022526-j9kg00qf 4926 3 at at IN cord-022526-j9kg00qf 4926 4 greatest great JJS cord-022526-j9kg00qf 4926 5 risk risk NN cord-022526-j9kg00qf 4926 6 of of IN cord-022526-j9kg00qf 4926 7 developing develop VBG cord-022526-j9kg00qf 4926 8 adhesions adhesion NNS cord-022526-j9kg00qf 4926 9 after after IN cord-022526-j9kg00qf 4926 10 colic colic NN cord-022526-j9kg00qf 4926 11 surgery surgery NN cord-022526-j9kg00qf 4926 12 appear appear VBP cord-022526-j9kg00qf 4926 13 to to TO cord-022526-j9kg00qf 4926 14 be be VB cord-022526-j9kg00qf 4926 15 those those DT cord-022526-j9kg00qf 4926 16 that that WDT cord-022526-j9kg00qf 4926 17 have have VBP cord-022526-j9kg00qf 4926 18 small small JJ cord-022526-j9kg00qf 4926 19 intestinal intestinal JJ cord-022526-j9kg00qf 4926 20 disease disease NN cord-022526-j9kg00qf 4926 21 . . . cord-022526-j9kg00qf 4927 1 51 51 CD cord-022526-j9kg00qf 4927 2 , , , cord-022526-j9kg00qf 4927 3 59 59 CD cord-022526-j9kg00qf 4928 1 In in IN cord-022526-j9kg00qf 4928 2 one one CD cord-022526-j9kg00qf 4928 3 study study NN cord-022526-j9kg00qf 4928 4 of of IN cord-022526-j9kg00qf 4928 5 horses horse NNS cord-022526-j9kg00qf 4928 6 undergoing undergo VBG cord-022526-j9kg00qf 4928 7 surgical surgical JJ cord-022526-j9kg00qf 4928 8 correction correction NN cord-022526-j9kg00qf 4928 9 of of IN cord-022526-j9kg00qf 4928 10 small small JJ cord-022526-j9kg00qf 4928 11 intestinal intestinal JJ cord-022526-j9kg00qf 4928 12 obstruction obstruction NN cord-022526-j9kg00qf 4928 13 , , , cord-022526-j9kg00qf 4928 14 22 22 CD cord-022526-j9kg00qf 4928 15 % % NN cord-022526-j9kg00qf 4928 16 developed develop VBD cord-022526-j9kg00qf 4928 17 a a DT cord-022526-j9kg00qf 4928 18 surgical surgical JJ cord-022526-j9kg00qf 4928 19 lesion lesion NN cord-022526-j9kg00qf 4928 20 associated associate VBN cord-022526-j9kg00qf 4928 21 with with IN cord-022526-j9kg00qf 4928 22 adhesions adhesion NNS cord-022526-j9kg00qf 4928 23 . . . cord-022526-j9kg00qf 4929 1 Foals foal NNS cord-022526-j9kg00qf 4929 2 appear appear VBP cord-022526-j9kg00qf 4929 3 to to TO cord-022526-j9kg00qf 4929 4 have have VB cord-022526-j9kg00qf 4929 5 an an DT cord-022526-j9kg00qf 4929 6 increased increase VBN cord-022526-j9kg00qf 4929 7 incidence incidence NN cord-022526-j9kg00qf 4929 8 of of IN cord-022526-j9kg00qf 4929 9 adhesions adhesion NNS cord-022526-j9kg00qf 4929 10 compared compare VBN cord-022526-j9kg00qf 4929 11 with with IN cord-022526-j9kg00qf 4929 12 mature mature JJ cord-022526-j9kg00qf 4929 13 horses horse NNS cord-022526-j9kg00qf 4929 14 regardless regardless RB cord-022526-j9kg00qf 4929 15 of of IN cord-022526-j9kg00qf 4929 16 the the DT cord-022526-j9kg00qf 4929 17 nature nature NN cord-022526-j9kg00qf 4929 18 of of IN cord-022526-j9kg00qf 4929 19 the the DT cord-022526-j9kg00qf 4929 20 abdominal abdominal JJ cord-022526-j9kg00qf 4929 21 surgery surgery NN cord-022526-j9kg00qf 4929 22 . . . cord-022526-j9kg00qf 4930 1 51 51 CD cord-022526-j9kg00qf 4931 1 One one CD cord-022526-j9kg00qf 4931 2 study study NN cord-022526-j9kg00qf 4931 3 indicated indicate VBD cord-022526-j9kg00qf 4931 4 that that IN cord-022526-j9kg00qf 4931 5 17 17 CD cord-022526-j9kg00qf 4931 6 % % NN cord-022526-j9kg00qf 4931 7 of of IN cord-022526-j9kg00qf 4931 8 foals foal NNS cord-022526-j9kg00qf 4931 9 developed develop VBD cord-022526-j9kg00qf 4931 10 lesions lesion NNS cord-022526-j9kg00qf 4931 11 attributable attributable JJ cord-022526-j9kg00qf 4931 12 to to IN cord-022526-j9kg00qf 4931 13 adhesions adhesion NNS cord-022526-j9kg00qf 4931 14 regardless regardless RB cord-022526-j9kg00qf 4931 15 of of IN cord-022526-j9kg00qf 4931 16 the the DT cord-022526-j9kg00qf 4931 17 type type NN cord-022526-j9kg00qf 4931 18 of of IN cord-022526-j9kg00qf 4931 19 initial initial JJ cord-022526-j9kg00qf 4931 20 surgery surgery NN cord-022526-j9kg00qf 4931 21 . . . cord-022526-j9kg00qf 4932 1 60 60 CD cord-022526-j9kg00qf 4932 2 Studies study NNS cord-022526-j9kg00qf 4932 3 conflict conflict NN cord-022526-j9kg00qf 4932 4 as as IN cord-022526-j9kg00qf 4932 5 to to IN cord-022526-j9kg00qf 4932 6 whether whether IN cord-022526-j9kg00qf 4932 7 the the DT cord-022526-j9kg00qf 4932 8 degree degree NN cord-022526-j9kg00qf 4932 9 of of IN cord-022526-j9kg00qf 4932 10 surgical surgical JJ cord-022526-j9kg00qf 4932 11 intervention intervention NN cord-022526-j9kg00qf 4932 12 influences influence VBZ cord-022526-j9kg00qf 4932 13 adhesion adhesion NN cord-022526-j9kg00qf 4932 14 formation formation NN cord-022526-j9kg00qf 4932 15 , , , cord-022526-j9kg00qf 4932 16 51 51 CD cord-022526-j9kg00qf 4932 17 but but CC cord-022526-j9kg00qf 4932 18 in in IN cord-022526-j9kg00qf 4932 19 one one CD cord-022526-j9kg00qf 4932 20 study study NN cord-022526-j9kg00qf 4932 21 , , , cord-022526-j9kg00qf 4932 22 horses horse NNS cord-022526-j9kg00qf 4932 23 that that WDT cord-022526-j9kg00qf 4932 24 require require VBP cord-022526-j9kg00qf 4932 25 enterotomy enterotomy NN cord-022526-j9kg00qf 4932 26 or or CC cord-022526-j9kg00qf 4932 27 resection resection NN cord-022526-j9kg00qf 4932 28 and and CC cord-022526-j9kg00qf 4932 29 anastomosis anastomosis NN cord-022526-j9kg00qf 4932 30 were be VBD cord-022526-j9kg00qf 4932 31 at at IN cord-022526-j9kg00qf 4932 32 greatest great JJS cord-022526-j9kg00qf 4932 33 risk risk NN cord-022526-j9kg00qf 4932 34 of of IN cord-022526-j9kg00qf 4932 35 developing develop VBG cord-022526-j9kg00qf 4932 36 adhesions adhesion NNS cord-022526-j9kg00qf 4932 37 . . . cord-022526-j9kg00qf 4933 1 59 59 CD cord-022526-j9kg00qf 4934 1 As as IN cord-022526-j9kg00qf 4934 2 an an DT cord-022526-j9kg00qf 4934 3 indication indication NN cord-022526-j9kg00qf 4934 4 of of IN cord-022526-j9kg00qf 4934 5 the the DT cord-022526-j9kg00qf 4934 6 importance importance NN cord-022526-j9kg00qf 4934 7 of of IN cord-022526-j9kg00qf 4934 8 postoperative postoperative JJ cord-022526-j9kg00qf 4934 9 adhesion adhesion NN cord-022526-j9kg00qf 4934 10 formation formation NN cord-022526-j9kg00qf 4934 11 , , , cord-022526-j9kg00qf 4934 12 adhesions adhesion NNS cord-022526-j9kg00qf 4934 13 were be VBD cord-022526-j9kg00qf 4934 14 among among IN cord-022526-j9kg00qf 4934 15 the the DT cord-022526-j9kg00qf 4934 16 most most RBS cord-022526-j9kg00qf 4934 17 common common JJ cord-022526-j9kg00qf 4934 18 reasons reason NNS cord-022526-j9kg00qf 4934 19 for for IN cord-022526-j9kg00qf 4934 20 repeat repeat NN cord-022526-j9kg00qf 4934 21 laparotomy laparotomy NN cord-022526-j9kg00qf 4934 22 in in IN cord-022526-j9kg00qf 4934 23 postoperative postoperative JJ cord-022526-j9kg00qf 4934 24 colic colic NN cord-022526-j9kg00qf 4934 25 patients patient NNS cord-022526-j9kg00qf 4934 26 . . . cord-022526-j9kg00qf 4935 1 59 59 CD cord-022526-j9kg00qf 4935 2 , , , cord-022526-j9kg00qf 4935 3 61 61 CD cord-022526-j9kg00qf 4935 4 Clinical clinical JJ cord-022526-j9kg00qf 4935 5 signs sign NNS cord-022526-j9kg00qf 4935 6 of of IN cord-022526-j9kg00qf 4935 7 horses horse NNS cord-022526-j9kg00qf 4935 8 with with IN cord-022526-j9kg00qf 4935 9 adhesions adhesion NNS cord-022526-j9kg00qf 4935 10 vary vary VBP cord-022526-j9kg00qf 4935 11 greatly greatly RB cord-022526-j9kg00qf 4935 12 depending depend VBG cord-022526-j9kg00qf 4935 13 on on IN cord-022526-j9kg00qf 4935 14 whether whether IN cord-022526-j9kg00qf 4935 15 the the DT cord-022526-j9kg00qf 4935 16 adhesion adhesion NN cord-022526-j9kg00qf 4935 17 is be VBZ cord-022526-j9kg00qf 4935 18 causing cause VBG cord-022526-j9kg00qf 4935 19 partial partial JJ cord-022526-j9kg00qf 4935 20 obstruction obstruction NN cord-022526-j9kg00qf 4935 21 or or CC cord-022526-j9kg00qf 4935 22 complete complete JJ cord-022526-j9kg00qf 4935 23 luminal luminal JJ cord-022526-j9kg00qf 4935 24 obstruction obstruction NN cord-022526-j9kg00qf 4935 25 or or CC cord-022526-j9kg00qf 4935 26 involves involve VBZ cord-022526-j9kg00qf 4935 27 intestinal intestinal JJ cord-022526-j9kg00qf 4935 28 vasculature vasculature NN cord-022526-j9kg00qf 4935 29 . . . cord-022526-j9kg00qf 4936 1 Adhesions adhesion NNS cord-022526-j9kg00qf 4936 2 would would MD cord-022526-j9kg00qf 4936 3 be be VB cord-022526-j9kg00qf 4936 4 an an DT cord-022526-j9kg00qf 4936 5 important important JJ cord-022526-j9kg00qf 4936 6 differential differential JJ cord-022526-j9kg00qf 4936 7 diagnosis diagnosis NN cord-022526-j9kg00qf 4936 8 for for IN cord-022526-j9kg00qf 4936 9 intermittent intermittent JJ cord-022526-j9kg00qf 4936 10 colic colic NN cord-022526-j9kg00qf 4936 11 in in IN cord-022526-j9kg00qf 4936 12 the the DT cord-022526-j9kg00qf 4936 13 postoperative postoperative JJ cord-022526-j9kg00qf 4936 14 period period NN cord-022526-j9kg00qf 4936 15 , , , cord-022526-j9kg00qf 4936 16 particularly particularly RB cord-022526-j9kg00qf 4936 17 if if IN cord-022526-j9kg00qf 4936 18 such such JJ cord-022526-j9kg00qf 4936 19 colic colic NN cord-022526-j9kg00qf 4936 20 was be VBD cord-022526-j9kg00qf 4936 21 not not RB cord-022526-j9kg00qf 4936 22 relieved relieve VBN cord-022526-j9kg00qf 4936 23 by by IN cord-022526-j9kg00qf 4936 24 nasogastric nasogastric NN cord-022526-j9kg00qf 4936 25 decompression decompression NN cord-022526-j9kg00qf 4936 26 of of IN cord-022526-j9kg00qf 4936 27 the the DT cord-022526-j9kg00qf 4936 28 stomach stomach NN cord-022526-j9kg00qf 4936 29 . . . cord-022526-j9kg00qf 4937 1 Continued continue VBN cord-022526-j9kg00qf 4937 2 intermittent intermittent JJ cord-022526-j9kg00qf 4937 3 colic colic NN cord-022526-j9kg00qf 4937 4 should should MD cord-022526-j9kg00qf 4937 5 prompt prompt VB cord-022526-j9kg00qf 4937 6 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 4937 7 to to TO cord-022526-j9kg00qf 4937 8 determine determine VB cord-022526-j9kg00qf 4937 9 if if IN cord-022526-j9kg00qf 4937 10 septic septic JJ cord-022526-j9kg00qf 4937 11 peritonitis peritonitis NN cord-022526-j9kg00qf 4937 12 is be VBZ cord-022526-j9kg00qf 4937 13 present present JJ cord-022526-j9kg00qf 4937 14 , , , cord-022526-j9kg00qf 4937 15 which which WDT cord-022526-j9kg00qf 4937 16 may may MD cord-022526-j9kg00qf 4937 17 contribute contribute VB cord-022526-j9kg00qf 4937 18 to to IN cord-022526-j9kg00qf 4937 19 adhesion adhesion NN cord-022526-j9kg00qf 4937 20 formation formation NN cord-022526-j9kg00qf 4937 21 . . . cord-022526-j9kg00qf 4938 1 Placement placement NN cord-022526-j9kg00qf 4938 2 of of IN cord-022526-j9kg00qf 4938 3 a a DT cord-022526-j9kg00qf 4938 4 large large JJ cord-022526-j9kg00qf 4938 5 bore bore NN cord-022526-j9kg00qf 4938 6 drain drain NN cord-022526-j9kg00qf 4938 7 and and CC cord-022526-j9kg00qf 4938 8 peritoneal peritoneal JJ cord-022526-j9kg00qf 4938 9 lavage lavage NN cord-022526-j9kg00qf 4938 10 ( ( -LRB- cord-022526-j9kg00qf 4938 11 Figure figure NN cord-022526-j9kg00qf 4938 12 13 13 CD cord-022526-j9kg00qf 4938 13 surgery surgery NN cord-022526-j9kg00qf 4938 14 should should MD cord-022526-j9kg00qf 4938 15 prompt prompt VB cord-022526-j9kg00qf 4938 16 immediate immediate JJ cord-022526-j9kg00qf 4938 17 nasogastric nasogastric NN cord-022526-j9kg00qf 4938 18 intubation intubation NN cord-022526-j9kg00qf 4938 19 to to TO cord-022526-j9kg00qf 4938 20 decompress decompress VB cord-022526-j9kg00qf 4938 21 the the DT cord-022526-j9kg00qf 4938 22 stomach stomach NN cord-022526-j9kg00qf 4938 23 . . . cord-022526-j9kg00qf 4939 1 Treatment treatment NN cord-022526-j9kg00qf 4939 2 should should MD cord-022526-j9kg00qf 4939 3 include include VB cord-022526-j9kg00qf 4939 4 attempts attempt NNS cord-022526-j9kg00qf 4939 5 at at IN cord-022526-j9kg00qf 4939 6 obtaining obtain VBG cord-022526-j9kg00qf 4939 7 reflux reflux NN cord-022526-j9kg00qf 4939 8 from from IN cord-022526-j9kg00qf 4939 9 the the DT cord-022526-j9kg00qf 4939 10 horse horse NN cord-022526-j9kg00qf 4939 11 at at IN cord-022526-j9kg00qf 4939 12 frequent frequent JJ cord-022526-j9kg00qf 4939 13 intervals interval NNS cord-022526-j9kg00qf 4939 14 rather rather RB cord-022526-j9kg00qf 4939 15 than than IN cord-022526-j9kg00qf 4939 16 relying rely VBG cord-022526-j9kg00qf 4939 17 on on IN cord-022526-j9kg00qf 4939 18 passive passive JJ cord-022526-j9kg00qf 4939 19 flow flow NN cord-022526-j9kg00qf 4939 20 of of IN cord-022526-j9kg00qf 4939 21 reflux reflux NN cord-022526-j9kg00qf 4939 22 . . . cord-022526-j9kg00qf 4940 1 In in IN cord-022526-j9kg00qf 4940 2 addition addition NN cord-022526-j9kg00qf 4940 3 , , , cord-022526-j9kg00qf 4940 4 administration administration NN cord-022526-j9kg00qf 4940 5 of of IN cord-022526-j9kg00qf 4940 6 intravenous intravenous JJ cord-022526-j9kg00qf 4940 7 fluids fluid NNS cord-022526-j9kg00qf 4940 8 should should MD cord-022526-j9kg00qf 4940 9 account account VB cord-022526-j9kg00qf 4940 10 for for IN cord-022526-j9kg00qf 4940 11 the the DT cord-022526-j9kg00qf 4940 12 maintenance maintenance NN cord-022526-j9kg00qf 4940 13 requirement requirement NN cord-022526-j9kg00qf 4940 14 ( ( -LRB- cord-022526-j9kg00qf 4940 15 50 50 CD cord-022526-j9kg00qf 4940 16 ml ml NNS cord-022526-j9kg00qf 4940 17 / / SYM cord-022526-j9kg00qf 4940 18 kg kg NN cord-022526-j9kg00qf 4940 19 / / SYM cord-022526-j9kg00qf 4940 20 day day NN cord-022526-j9kg00qf 4940 21 , , , cord-022526-j9kg00qf 4940 22 about about RB cord-022526-j9kg00qf 4940 23 1 1 CD cord-022526-j9kg00qf 4940 24 L l NN cord-022526-j9kg00qf 4940 25 / / SYM cord-022526-j9kg00qf 4940 26 hr hr NN cord-022526-j9kg00qf 4940 27 in in IN cord-022526-j9kg00qf 4940 28 the the DT cord-022526-j9kg00qf 4940 29 average average JJ cord-022526-j9kg00qf 4940 30 horse horse NN cord-022526-j9kg00qf 4940 31 ) ) -RRB- cord-022526-j9kg00qf 4940 32 and and CC cord-022526-j9kg00qf 4940 33 fluid fluid JJ cord-022526-j9kg00qf 4940 34 losses loss NNS cord-022526-j9kg00qf 4940 35 via via IN cord-022526-j9kg00qf 4940 36 reflux reflux NN cord-022526-j9kg00qf 4940 37 . . . cord-022526-j9kg00qf 4941 1 In in IN cord-022526-j9kg00qf 4941 2 practice practice NN cord-022526-j9kg00qf 4941 3 , , , cord-022526-j9kg00qf 4941 4 this this DT cord-022526-j9kg00qf 4941 5 requires require VBZ cord-022526-j9kg00qf 4941 6 frequent frequent JJ cord-022526-j9kg00qf 4941 7 monitoring monitoring NN cord-022526-j9kg00qf 4941 8 of of IN cord-022526-j9kg00qf 4941 9 packed pack VBN cord-022526-j9kg00qf 4941 10 cell cell NN cord-022526-j9kg00qf 4941 11 volume volume NN cord-022526-j9kg00qf 4941 12 and and CC cord-022526-j9kg00qf 4941 13 total total JJ cord-022526-j9kg00qf 4941 14 protein protein NN cord-022526-j9kg00qf 4941 15 to to TO cord-022526-j9kg00qf 4941 16 ensure ensure VB cord-022526-j9kg00qf 4941 17 that that IN cord-022526-j9kg00qf 4941 18 the the DT cord-022526-j9kg00qf 4941 19 horse horse NN cord-022526-j9kg00qf 4941 20 remains remain VBZ cord-022526-j9kg00qf 4941 21 well well RB cord-022526-j9kg00qf 4941 22 hydrated hydrated JJ cord-022526-j9kg00qf 4941 23 . . . cord-022526-j9kg00qf 4942 1 Although although IN cord-022526-j9kg00qf 4942 2 concerns concern NNS cord-022526-j9kg00qf 4942 3 have have VBP cord-022526-j9kg00qf 4942 4 arisen arise VBN cord-022526-j9kg00qf 4942 5 that that IN cord-022526-j9kg00qf 4942 6 overhydrating overhydrate VBG cord-022526-j9kg00qf 4942 7 horses horse NNS cord-022526-j9kg00qf 4942 8 may may MD cord-022526-j9kg00qf 4942 9 contribute contribute VB cord-022526-j9kg00qf 4942 10 to to IN cord-022526-j9kg00qf 4942 11 increased increase VBN cord-022526-j9kg00qf 4942 12 nasogastric nasogastric NN cord-022526-j9kg00qf 4942 13 reflux reflux NN cord-022526-j9kg00qf 4942 14 , , , cord-022526-j9kg00qf 4942 15 42 42 CD cord-022526-j9kg00qf 4942 16 keeping keep VBG cord-022526-j9kg00qf 4942 17 horses horse NNS cord-022526-j9kg00qf 4942 18 well well RB cord-022526-j9kg00qf 4942 19 - - HYPH cord-022526-j9kg00qf 4942 20 hydrated hydrate VBN cord-022526-j9kg00qf 4942 21 to to TO cord-022526-j9kg00qf 4942 22 avoid avoid VB cord-022526-j9kg00qf 4942 23 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 4942 24 shock shock NN cord-022526-j9kg00qf 4942 25 is be VBZ cord-022526-j9kg00qf 4942 26 critical critical JJ cord-022526-j9kg00qf 4942 27 . . . cord-022526-j9kg00qf 4943 1 Additionally additionally RB cord-022526-j9kg00qf 4943 2 , , , cord-022526-j9kg00qf 4943 3 one one PRP cord-022526-j9kg00qf 4943 4 should should MD cord-022526-j9kg00qf 4943 5 monitor monitor VB cord-022526-j9kg00qf 4943 6 electrolytes electrolyte NNS cord-022526-j9kg00qf 4943 7 frequently frequently RB cord-022526-j9kg00qf 4943 8 , , , cord-022526-j9kg00qf 4943 9 particularly particularly RB cord-022526-j9kg00qf 4943 10 considering consider VBG cord-022526-j9kg00qf 4943 11 their -PRON- PRP$ cord-022526-j9kg00qf 4943 12 potential potential JJ cord-022526-j9kg00qf 4943 13 role role NN cord-022526-j9kg00qf 4943 14 in in IN cord-022526-j9kg00qf 4943 15 smooth smooth JJ cord-022526-j9kg00qf 4943 16 muscle muscle NN cord-022526-j9kg00qf 4943 17 contraction contraction NN cord-022526-j9kg00qf 4943 18 and and CC cord-022526-j9kg00qf 4943 19 nerve nerve NN cord-022526-j9kg00qf 4943 20 excitability excitability NN cord-022526-j9kg00qf 4943 21 . . . cord-022526-j9kg00qf 4944 1 Because because IN cord-022526-j9kg00qf 4944 2 of of IN cord-022526-j9kg00qf 4944 3 the the DT cord-022526-j9kg00qf 4944 4 important important JJ cord-022526-j9kg00qf 4944 5 role role NN cord-022526-j9kg00qf 4944 6 of of IN cord-022526-j9kg00qf 4944 7 inflammation inflammation NN cord-022526-j9kg00qf 4944 8 in in IN cord-022526-j9kg00qf 4944 9 postoperative postoperative JJ cord-022526-j9kg00qf 4944 10 ileus ileus NN cord-022526-j9kg00qf 4944 11 , , , cord-022526-j9kg00qf 4944 12 including include VBG cord-022526-j9kg00qf 4944 13 elaboration elaboration NN cord-022526-j9kg00qf 4944 14 of of IN cord-022526-j9kg00qf 4944 15 COX-2-produced cox-2-produced JJ cord-022526-j9kg00qf 4944 16 prostanoids prostanoid NNS cord-022526-j9kg00qf 4944 17 , , , cord-022526-j9kg00qf 4944 18 70 70 CD cord-022526-j9kg00qf 4944 19 administration administration NN cord-022526-j9kg00qf 4944 20 of of IN cord-022526-j9kg00qf 4944 21 NSAIDs NSAIDs NNP cord-022526-j9kg00qf 4944 22 is be VBZ cord-022526-j9kg00qf 4944 23 indicated indicate VBN cord-022526-j9kg00qf 4944 24 . . . cord-022526-j9kg00qf 4945 1 NSAID NSAID NNP cord-022526-j9kg00qf 4945 2 administration administration NN cord-022526-j9kg00qf 4945 3 is be VBZ cord-022526-j9kg00qf 4945 4 particularly particularly RB cord-022526-j9kg00qf 4945 5 necessary necessary JJ cord-022526-j9kg00qf 4945 6 if if IN cord-022526-j9kg00qf 4945 7 postoperative postoperative JJ cord-022526-j9kg00qf 4945 8 ileus ileus NN cord-022526-j9kg00qf 4945 9 is be VBZ cord-022526-j9kg00qf 4945 10 associated associate VBN cord-022526-j9kg00qf 4945 11 with with IN cord-022526-j9kg00qf 4945 12 endotoxemia endotoxemia NN cord-022526-j9kg00qf 4945 13 , , , cord-022526-j9kg00qf 4945 14 because because IN cord-022526-j9kg00qf 4945 15 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 4945 16 - - HYPH cord-022526-j9kg00qf 4945 17 induced induce VBN cord-022526-j9kg00qf 4945 18 prostanoid prostanoid JJ cord-022526-j9kg00qf 4945 19 production production NN cord-022526-j9kg00qf 4945 20 disrupts disrupt VBZ cord-022526-j9kg00qf 4945 21 propulsive propulsive JJ cord-022526-j9kg00qf 4945 22 motility motility NN cord-022526-j9kg00qf 4945 23 in in IN cord-022526-j9kg00qf 4945 24 horses horse NNS cord-022526-j9kg00qf 4945 25 . . . cord-022526-j9kg00qf 4946 1 71 71 CD cord-022526-j9kg00qf 4946 2 , , , cord-022526-j9kg00qf 4946 3 72 72 CD cord-022526-j9kg00qf 4947 1 Interestingly interestingly RB cord-022526-j9kg00qf 4947 2 , , , cord-022526-j9kg00qf 4947 3 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4947 4 is be VBZ cord-022526-j9kg00qf 4947 5 more more RBR cord-022526-j9kg00qf 4947 6 effective effective JJ cord-022526-j9kg00qf 4947 7 than than IN cord-022526-j9kg00qf 4947 8 flunixin flunixin NNP cord-022526-j9kg00qf 4947 9 meglumine meglumine NNP cord-022526-j9kg00qf 4947 10 at at IN cord-022526-j9kg00qf 4947 11 reducing reduce VBG cord-022526-j9kg00qf 4947 12 the the DT cord-022526-j9kg00qf 4947 13 deleterious deleterious JJ cord-022526-j9kg00qf 4947 14 actions action NNS cord-022526-j9kg00qf 4947 15 of of IN cord-022526-j9kg00qf 4947 16 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 4947 17 on on IN cord-022526-j9kg00qf 4947 18 intestinal intestinal JJ cord-022526-j9kg00qf 4947 19 motility motility NN cord-022526-j9kg00qf 4947 20 . . . cord-022526-j9kg00qf 4948 1 73 73 CD cord-022526-j9kg00qf 4949 1 However however RB cord-022526-j9kg00qf 4949 2 , , , cord-022526-j9kg00qf 4949 3 one one PRP cord-022526-j9kg00qf 4949 4 should should MD cord-022526-j9kg00qf 4949 5 use use VB cord-022526-j9kg00qf 4949 6 caution caution NN cord-022526-j9kg00qf 4949 7 when when WRB cord-022526-j9kg00qf 4949 8 administering administer VBG cord-022526-j9kg00qf 4949 9 NSAIDs nsaid NNS cord-022526-j9kg00qf 4949 10 to to IN cord-022526-j9kg00qf 4949 11 patients patient NNS cord-022526-j9kg00qf 4949 12 with with IN cord-022526-j9kg00qf 4949 13 postoperative postoperative JJ cord-022526-j9kg00qf 4949 14 ileus ileus NN cord-022526-j9kg00qf 4949 15 in in IN cord-022526-j9kg00qf 4949 16 light light NN cord-022526-j9kg00qf 4949 17 of of IN cord-022526-j9kg00qf 4949 18 research research NN cord-022526-j9kg00qf 4949 19 suggesting suggest VBG cord-022526-j9kg00qf 4949 20 that that IN cord-022526-j9kg00qf 4949 21 complete complete JJ cord-022526-j9kg00qf 4949 22 inhibition inhibition NN cord-022526-j9kg00qf 4949 23 of of IN cord-022526-j9kg00qf 4949 24 prostanoid prostanoid JJ cord-022526-j9kg00qf 4949 25 production production NN cord-022526-j9kg00qf 4949 26 can can MD cord-022526-j9kg00qf 4949 27 alter alter VB cord-022526-j9kg00qf 4949 28 motility motility NN cord-022526-j9kg00qf 4949 29 patterns pattern NNS cord-022526-j9kg00qf 4949 30 in in IN cord-022526-j9kg00qf 4949 31 normal normal JJ cord-022526-j9kg00qf 4949 32 equine equine JJ cord-022526-j9kg00qf 4949 33 intestine intestine NN cord-022526-j9kg00qf 4949 34 . . . cord-022526-j9kg00qf 4950 1 68 68 CD cord-022526-j9kg00qf 4951 1 The the DT cord-022526-j9kg00qf 4951 2 advent advent NN cord-022526-j9kg00qf 4951 3 of of IN cord-022526-j9kg00qf 4951 4 selective selective JJ cord-022526-j9kg00qf 4951 5 COX-2 COX-2 NNP cord-022526-j9kg00qf 4951 6 inhibitors inhibitor NNS cord-022526-j9kg00qf 4951 7 may may MD cord-022526-j9kg00qf 4951 8 provide provide VB cord-022526-j9kg00qf 4951 9 optimal optimal JJ cord-022526-j9kg00qf 4951 10 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 4951 11 treatment treatment NN cord-022526-j9kg00qf 4951 12 in in IN cord-022526-j9kg00qf 4951 13 the the DT cord-022526-j9kg00qf 4951 14 future future NN cord-022526-j9kg00qf 4951 15 . . . cord-022526-j9kg00qf 4952 1 74 74 CD cord-022526-j9kg00qf 4952 2 Other other JJ cord-022526-j9kg00qf 4952 3 treatments treatment NNS cord-022526-j9kg00qf 4952 4 aimed aim VBN cord-022526-j9kg00qf 4952 5 at at IN cord-022526-j9kg00qf 4952 6 specifically specifically RB cord-022526-j9kg00qf 4952 7 modulating modulate VBG cord-022526-j9kg00qf 4952 8 intestinal intestinal JJ cord-022526-j9kg00qf 4952 9 motility motility NN cord-022526-j9kg00qf 4952 10 include include VBP cord-022526-j9kg00qf 4952 11 lidocaine lidocaine NN cord-022526-j9kg00qf 4952 12 ( ( -LRB- cord-022526-j9kg00qf 4952 13 bolus bolus NN cord-022526-j9kg00qf 4952 14 of of IN cord-022526-j9kg00qf 4952 15 1.3 1.3 CD cord-022526-j9kg00qf 4952 16 mg mg NNP cord-022526-j9kg00qf 4952 17 / / SYM cord-022526-j9kg00qf 4952 18 kg kg NNS cord-022526-j9kg00qf 4952 19 followed follow VBD cord-022526-j9kg00qf 4952 20 by by IN cord-022526-j9kg00qf 4952 21 0.05 0.05 CD cord-022526-j9kg00qf 4952 22 mg mg NNP cord-022526-j9kg00qf 4952 23 / / SYM cord-022526-j9kg00qf 4952 24 kg kg NNP cord-022526-j9kg00qf 4952 25 / / SYM cord-022526-j9kg00qf 4952 26 min min NN cord-022526-j9kg00qf 4952 27 for for IN cord-022526-j9kg00qf 4952 28 24 24 CD cord-022526-j9kg00qf 4952 29 hours hour NNS cord-022526-j9kg00qf 4952 30 ) ) -RRB- cord-022526-j9kg00qf 4952 31 , , , cord-022526-j9kg00qf 4952 32 erythromycin erythromycin JJ cord-022526-j9kg00qf 4952 33 ( ( -LRB- cord-022526-j9kg00qf 4952 34 0.5 0.5 CD cord-022526-j9kg00qf 4952 35 to to TO cord-022526-j9kg00qf 4952 36 1.0 1.0 CD cord-022526-j9kg00qf 4952 37 mg mg NNS cord-022526-j9kg00qf 4952 38 / / SYM cord-022526-j9kg00qf 4952 39 kg kg NNS cord-022526-j9kg00qf 4952 40 slow slow JJ cord-022526-j9kg00qf 4952 41 intravenous intravenous JJ cord-022526-j9kg00qf 4952 42 infusion infusion NN cord-022526-j9kg00qf 4952 43 in in IN cord-022526-j9kg00qf 4952 44 1 1 CD cord-022526-j9kg00qf 4952 45 L L NNP cord-022526-j9kg00qf 4952 46 saline saline NN cord-022526-j9kg00qf 4952 47 every every DT cord-022526-j9kg00qf 4952 48 6 6 CD cord-022526-j9kg00qf 4952 49 hours hour NNS cord-022526-j9kg00qf 4952 50 ) ) -RRB- cord-022526-j9kg00qf 4952 51 , , , cord-022526-j9kg00qf 4952 52 and and CC cord-022526-j9kg00qf 4952 53 metoclopramide metoclopramide NN cord-022526-j9kg00qf 4952 54 ( ( -LRB- cord-022526-j9kg00qf 4952 55 0.04 0.04 CD cord-022526-j9kg00qf 4952 56 mg mg NNP cord-022526-j9kg00qf 4952 57 / / SYM cord-022526-j9kg00qf 4952 58 kg kg NNP cord-022526-j9kg00qf 4952 59 / / SYM cord-022526-j9kg00qf 4952 60 hr hr NN cord-022526-j9kg00qf 4952 61 ) ) -RRB- cord-022526-j9kg00qf 4952 62 . . . cord-022526-j9kg00qf 4953 1 66 66 CD cord-022526-j9kg00qf 4953 2 , , , cord-022526-j9kg00qf 4953 3 75 75 CD cord-022526-j9kg00qf 4953 4 , , , cord-022526-j9kg00qf 4953 5 76 76 CD cord-022526-j9kg00qf 4954 1 The the DT cord-022526-j9kg00qf 4954 2 mechanism mechanism NN cord-022526-j9kg00qf 4954 3 of of IN cord-022526-j9kg00qf 4954 4 lidocaine lidocaine NN cord-022526-j9kg00qf 4954 5 is be VBZ cord-022526-j9kg00qf 4954 6 presumed presume VBN cord-022526-j9kg00qf 4954 7 to to TO cord-022526-j9kg00qf 4954 8 be be VB cord-022526-j9kg00qf 4954 9 inhibition inhibition NN cord-022526-j9kg00qf 4954 10 of of IN cord-022526-j9kg00qf 4954 11 sensory sensory JJ cord-022526-j9kg00qf 4954 12 nerve nerve NN cord-022526-j9kg00qf 4954 13 activity activity NN cord-022526-j9kg00qf 4954 14 within within IN cord-022526-j9kg00qf 4954 15 the the DT cord-022526-j9kg00qf 4954 16 wall wall NN cord-022526-j9kg00qf 4954 17 of of IN cord-022526-j9kg00qf 4954 18 the the DT cord-022526-j9kg00qf 4954 19 intestine intestine NN cord-022526-j9kg00qf 4954 20 , , , cord-022526-j9kg00qf 4954 21 thereby thereby RB cord-022526-j9kg00qf 4954 22 reducing reduce VBG cord-022526-j9kg00qf 4954 23 reflex reflex NN cord-022526-j9kg00qf 4954 24 sympathetic sympathetic JJ cord-022526-j9kg00qf 4954 25 inhibitory inhibitory JJ cord-022526-j9kg00qf 4954 26 activity activity NN cord-022526-j9kg00qf 4954 27 . . . cord-022526-j9kg00qf 4955 1 In in IN cord-022526-j9kg00qf 4955 2 addition addition NN cord-022526-j9kg00qf 4955 3 , , , cord-022526-j9kg00qf 4955 4 intravenously intravenously RB cord-022526-j9kg00qf 4955 5 administered administer VBN cord-022526-j9kg00qf 4955 6 lidocaine lidocaine NN cord-022526-j9kg00qf 4955 7 appears appear VBZ cord-022526-j9kg00qf 4955 8 to to TO cord-022526-j9kg00qf 4955 9 be be VB cord-022526-j9kg00qf 4955 10 an an DT cord-022526-j9kg00qf 4955 11 effective effective JJ cord-022526-j9kg00qf 4955 12 analgesic analgesic NN cord-022526-j9kg00qf 4955 13 . . . cord-022526-j9kg00qf 4956 1 Thus thus RB cord-022526-j9kg00qf 4956 2 an an DT cord-022526-j9kg00qf 4956 3 important important JJ cord-022526-j9kg00qf 4956 4 feature feature NN cord-022526-j9kg00qf 4956 5 of of IN cord-022526-j9kg00qf 4956 6 intravenous intravenous JJ cord-022526-j9kg00qf 4956 7 lidocaine lidocaine NN cord-022526-j9kg00qf 4956 8 therapy therapy NN cord-022526-j9kg00qf 4956 9 may may MD cord-022526-j9kg00qf 4956 10 be be VB cord-022526-j9kg00qf 4956 11 to to TO cord-022526-j9kg00qf 4956 12 control control VB cord-022526-j9kg00qf 4956 13 postoperative postoperative JJ cord-022526-j9kg00qf 4956 14 pain pain NN cord-022526-j9kg00qf 4956 15 - - HYPH cord-022526-j9kg00qf 4956 16 induced induce VBN cord-022526-j9kg00qf 4956 17 reduction reduction NN cord-022526-j9kg00qf 4956 18 of of IN cord-022526-j9kg00qf 4956 19 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4956 20 motility motility NN cord-022526-j9kg00qf 4956 21 and and CC cord-022526-j9kg00qf 4956 22 mucosal mucosal JJ cord-022526-j9kg00qf 4956 23 secretory secretory JJ cord-022526-j9kg00qf 4956 24 activity activity NN cord-022526-j9kg00qf 4956 25 . . . cord-022526-j9kg00qf 4957 1 77 77 CD cord-022526-j9kg00qf 4957 2 Metoclopramide Metoclopramide NNP cord-022526-j9kg00qf 4957 3 may may MD cord-022526-j9kg00qf 4957 4 stimulate stimulate VB cord-022526-j9kg00qf 4957 5 intestinal intestinal JJ cord-022526-j9kg00qf 4957 6 motility motility NN cord-022526-j9kg00qf 4957 7 by by IN cord-022526-j9kg00qf 4957 8 several several JJ cord-022526-j9kg00qf 4957 9 mechanisms mechanism NNS cord-022526-j9kg00qf 4957 10 , , , cord-022526-j9kg00qf 4957 11 including include VBG cord-022526-j9kg00qf 4957 12 dopamine dopamine NN cord-022526-j9kg00qf 4957 13 receptor receptor NN cord-022526-j9kg00qf 4957 14 blockade blockade NN cord-022526-j9kg00qf 4957 15 , , , cord-022526-j9kg00qf 4957 16 cholinergic cholinergic JJ cord-022526-j9kg00qf 4957 17 stimulation stimulation NN cord-022526-j9kg00qf 4957 18 , , , cord-022526-j9kg00qf 4957 19 and and CC cord-022526-j9kg00qf 4957 20 adrenergic adrenergic JJ cord-022526-j9kg00qf 4957 21 blockade blockade NN cord-022526-j9kg00qf 4957 22 . . . cord-022526-j9kg00qf 4958 1 66 66 CD cord-022526-j9kg00qf 4959 1 Although although IN cord-022526-j9kg00qf 4959 2 metoclopramide metoclopramide NN cord-022526-j9kg00qf 4959 3 has have VBZ cord-022526-j9kg00qf 4959 4 been be VBN cord-022526-j9kg00qf 4959 5 shown show VBN cord-022526-j9kg00qf 4959 6 to to TO cord-022526-j9kg00qf 4959 7 be be VB cord-022526-j9kg00qf 4959 8 beneficial beneficial JJ cord-022526-j9kg00qf 4959 9 for for IN cord-022526-j9kg00qf 4959 10 reversing reverse VBG cord-022526-j9kg00qf 4959 11 postoperative postoperative JJ cord-022526-j9kg00qf 4959 12 ileus ileus NN cord-022526-j9kg00qf 4959 13 in in IN cord-022526-j9kg00qf 4959 14 clinical clinical JJ cord-022526-j9kg00qf 4959 15 patients patient NNS cord-022526-j9kg00qf 4959 16 and and CC cord-022526-j9kg00qf 4959 17 research research NN cord-022526-j9kg00qf 4959 18 animals animal NNS cord-022526-j9kg00qf 4959 19 , , , cord-022526-j9kg00qf 4959 20 it -PRON- PRP cord-022526-j9kg00qf 4959 21 has have VBZ cord-022526-j9kg00qf 4959 22 central central JJ cord-022526-j9kg00qf 4959 23 nervous nervous JJ cord-022526-j9kg00qf 4959 24 system system NN cord-022526-j9kg00qf 4959 25 excitatory excitatory JJ cord-022526-j9kg00qf 4959 26 side side NN cord-022526-j9kg00qf 4959 27 effects effect NNS cord-022526-j9kg00qf 4959 28 in in IN cord-022526-j9kg00qf 4959 29 the the DT cord-022526-j9kg00qf 4959 30 horse horse NN cord-022526-j9kg00qf 4959 31 that that WDT cord-022526-j9kg00qf 4959 32 make make VBP cord-022526-j9kg00qf 4959 33 its -PRON- PRP$ cord-022526-j9kg00qf 4959 34 use use NN cord-022526-j9kg00qf 4959 35 difficult difficult JJ cord-022526-j9kg00qf 4959 36 . . . cord-022526-j9kg00qf 4960 1 Nonetheless nonetheless RB cord-022526-j9kg00qf 4960 2 , , , cord-022526-j9kg00qf 4960 3 administration administration NN cord-022526-j9kg00qf 4960 4 of of IN cord-022526-j9kg00qf 4960 5 metoclopramide metoclopramide NN cord-022526-j9kg00qf 4960 6 to to IN cord-022526-j9kg00qf 4960 7 horses horse NNS cord-022526-j9kg00qf 4960 8 with with IN cord-022526-j9kg00qf 4960 9 postoperative postoperative JJ cord-022526-j9kg00qf 4960 10 ileus ileus NN cord-022526-j9kg00qf 4960 11 resulted result VBD cord-022526-j9kg00qf 4960 12 in in IN cord-022526-j9kg00qf 4960 13 elect elect NN cord-022526-j9kg00qf 4960 14 repeat repeat VB cord-022526-j9kg00qf 4960 15 laparotomy laparotomy NN cord-022526-j9kg00qf 4960 16 or or CC cord-022526-j9kg00qf 4960 17 laparoscopy laparoscopy NN cord-022526-j9kg00qf 4960 18 . . . cord-022526-j9kg00qf 4961 1 In in IN cord-022526-j9kg00qf 4961 2 one one CD cord-022526-j9kg00qf 4961 3 study study NN cord-022526-j9kg00qf 4961 4 of of IN cord-022526-j9kg00qf 4961 5 adhesions adhesion NNS cord-022526-j9kg00qf 4961 6 , , , cord-022526-j9kg00qf 4961 7 70 70 CD cord-022526-j9kg00qf 4961 8 % % NN cord-022526-j9kg00qf 4961 9 of of IN cord-022526-j9kg00qf 4961 10 repeat repeat NN cord-022526-j9kg00qf 4961 11 laparotomies laparotomy NNS cord-022526-j9kg00qf 4961 12 were be VBD cord-022526-j9kg00qf 4961 13 performed perform VBN cord-022526-j9kg00qf 4961 14 within within IN cord-022526-j9kg00qf 4961 15 60 60 CD cord-022526-j9kg00qf 4961 16 days day NNS cord-022526-j9kg00qf 4961 17 , , , cord-022526-j9kg00qf 4961 18 suggesting suggest VBG cord-022526-j9kg00qf 4961 19 that that IN cord-022526-j9kg00qf 4961 20 surgical surgical JJ cord-022526-j9kg00qf 4961 21 colic colic NN cord-022526-j9kg00qf 4961 22 attributable attributable JJ cord-022526-j9kg00qf 4961 23 to to IN cord-022526-j9kg00qf 4961 24 adhesions adhesion NNS cord-022526-j9kg00qf 4961 25 typically typically RB cord-022526-j9kg00qf 4961 26 occurs occur VBZ cord-022526-j9kg00qf 4961 27 within within IN cord-022526-j9kg00qf 4961 28 2 2 CD cord-022526-j9kg00qf 4961 29 months month NNS cord-022526-j9kg00qf 4961 30 of of IN cord-022526-j9kg00qf 4961 31 an an DT cord-022526-j9kg00qf 4961 32 initial initial JJ cord-022526-j9kg00qf 4961 33 surgical surgical JJ cord-022526-j9kg00qf 4961 34 procedure procedure NN cord-022526-j9kg00qf 4961 35 . . . cord-022526-j9kg00qf 4962 1 Unfortunately unfortunately RB cord-022526-j9kg00qf 4962 2 , , , cord-022526-j9kg00qf 4962 3 the the DT cord-022526-j9kg00qf 4962 4 prognosis prognosis NN cord-022526-j9kg00qf 4962 5 for for IN cord-022526-j9kg00qf 4962 6 horses horse NNS cord-022526-j9kg00qf 4962 7 with with IN cord-022526-j9kg00qf 4962 8 colic colic NN cord-022526-j9kg00qf 4962 9 attributable attributable JJ cord-022526-j9kg00qf 4962 10 to to IN cord-022526-j9kg00qf 4962 11 adhesions adhesion NNS cord-022526-j9kg00qf 4962 12 is be VBZ cord-022526-j9kg00qf 4962 13 low low JJ cord-022526-j9kg00qf 4962 14 , , , cord-022526-j9kg00qf 4962 15 with with IN cord-022526-j9kg00qf 4962 16 only only RB cord-022526-j9kg00qf 4962 17 16 16 CD cord-022526-j9kg00qf 4962 18 % % NN cord-022526-j9kg00qf 4962 19 of of IN cord-022526-j9kg00qf 4962 20 horses horse NNS cord-022526-j9kg00qf 4962 21 in in IN cord-022526-j9kg00qf 4962 22 one one CD cord-022526-j9kg00qf 4962 23 study study NN cord-022526-j9kg00qf 4962 24 surviving survive VBG cord-022526-j9kg00qf 4962 25 from from IN cord-022526-j9kg00qf 4962 26 adhesion adhesion NN cord-022526-j9kg00qf 4962 27 - - HYPH cord-022526-j9kg00qf 4962 28 induced induce VBN cord-022526-j9kg00qf 4962 29 colic colic NN cord-022526-j9kg00qf 4962 30 . . . cord-022526-j9kg00qf 4963 1 51 51 CD cord-022526-j9kg00qf 4964 1 The the DT cord-022526-j9kg00qf 4964 2 definition definition NN cord-022526-j9kg00qf 4964 3 of of IN cord-022526-j9kg00qf 4964 4 ileus ileus NN cord-022526-j9kg00qf 4964 5 is be VBZ cord-022526-j9kg00qf 4964 6 intestinal intestinal JJ cord-022526-j9kg00qf 4964 7 obstruction obstruction NN cord-022526-j9kg00qf 4964 8 , , , cord-022526-j9kg00qf 4964 9 including include VBG cord-022526-j9kg00qf 4964 10 physical physical JJ cord-022526-j9kg00qf 4964 11 and and CC cord-022526-j9kg00qf 4964 12 functional functional JJ cord-022526-j9kg00qf 4964 13 obstructions obstruction NNS cord-022526-j9kg00qf 4964 14 . . . cord-022526-j9kg00qf 4965 1 However however RB cord-022526-j9kg00qf 4965 2 , , , cord-022526-j9kg00qf 4965 3 in in IN cord-022526-j9kg00qf 4965 4 veterinary veterinary JJ cord-022526-j9kg00qf 4965 5 medicine medicine NN cord-022526-j9kg00qf 4965 6 , , , cord-022526-j9kg00qf 4965 7 the the DT cord-022526-j9kg00qf 4965 8 term term NN cord-022526-j9kg00qf 4965 9 typically typically RB cord-022526-j9kg00qf 4965 10 is be VBZ cord-022526-j9kg00qf 4965 11 used use VBN cord-022526-j9kg00qf 4965 12 to to TO cord-022526-j9kg00qf 4965 13 designate designate VB cord-022526-j9kg00qf 4965 14 a a DT cord-022526-j9kg00qf 4965 15 lack lack NN cord-022526-j9kg00qf 4965 16 of of IN cord-022526-j9kg00qf 4965 17 progressive progressive JJ cord-022526-j9kg00qf 4965 18 aboral aboral JJ cord-022526-j9kg00qf 4965 19 propulsion propulsion NN cord-022526-j9kg00qf 4965 20 of of IN cord-022526-j9kg00qf 4965 21 ingesta ingesta NNP cord-022526-j9kg00qf 4965 22 resulting result VBG cord-022526-j9kg00qf 4965 23 in in IN cord-022526-j9kg00qf 4965 24 functional functional JJ cord-022526-j9kg00qf 4965 25 obstruction obstruction NN cord-022526-j9kg00qf 4965 26 . . . cord-022526-j9kg00qf 4966 1 62 62 CD cord-022526-j9kg00qf 4967 1 One one NN cord-022526-j9kg00qf 4967 2 typically typically RB cord-022526-j9kg00qf 4967 3 bases base VBZ cord-022526-j9kg00qf 4967 4 the the DT cord-022526-j9kg00qf 4967 5 diagnosis diagnosis NN cord-022526-j9kg00qf 4967 6 of of IN cord-022526-j9kg00qf 4967 7 postoperative postoperative JJ cord-022526-j9kg00qf 4967 8 ileus ileus NN cord-022526-j9kg00qf 4967 9 on on IN cord-022526-j9kg00qf 4967 10 the the DT cord-022526-j9kg00qf 4967 11 presence presence NN cord-022526-j9kg00qf 4967 12 of of IN cord-022526-j9kg00qf 4967 13 excessive excessive JJ cord-022526-j9kg00qf 4967 14 gastric gastric JJ cord-022526-j9kg00qf 4967 15 fluid fluid JJ cord-022526-j9kg00qf 4967 16 accumulation accumulation NN cord-022526-j9kg00qf 4967 17 ( ( -LRB- cord-022526-j9kg00qf 4967 18 reflected reflect VBN cord-022526-j9kg00qf 4967 19 as as IN cord-022526-j9kg00qf 4967 20 excessive excessive JJ cord-022526-j9kg00qf 4967 21 nasogastric nasogastric NN cord-022526-j9kg00qf 4967 22 reflux reflux NN cord-022526-j9kg00qf 4967 23 ) ) -RRB- cord-022526-j9kg00qf 4967 24 . . . cord-022526-j9kg00qf 4968 1 Postoperative postoperative JJ cord-022526-j9kg00qf 4968 2 ileus ileus NN cord-022526-j9kg00qf 4968 3 may may MD cord-022526-j9kg00qf 4968 4 occur occur VB cord-022526-j9kg00qf 4968 5 following follow VBG cord-022526-j9kg00qf 4968 6 any any DT cord-022526-j9kg00qf 4968 7 abdominal abdominal JJ cord-022526-j9kg00qf 4968 8 exploratory exploratory JJ cord-022526-j9kg00qf 4968 9 procedure procedure NN cord-022526-j9kg00qf 4968 10 . . . cord-022526-j9kg00qf 4969 1 However however RB cord-022526-j9kg00qf 4969 2 , , , cord-022526-j9kg00qf 4969 3 horses horse NNS cord-022526-j9kg00qf 4969 4 undergoing undergo VBG cord-022526-j9kg00qf 4969 5 surgery surgery NN cord-022526-j9kg00qf 4969 6 for for IN cord-022526-j9kg00qf 4969 7 strangulating strangulate VBG cord-022526-j9kg00qf 4969 8 small small JJ cord-022526-j9kg00qf 4969 9 intestinal intestinal JJ cord-022526-j9kg00qf 4969 10 lesions lesion NNS cord-022526-j9kg00qf 4969 11 or or CC cord-022526-j9kg00qf 4969 12 small small JJ cord-022526-j9kg00qf 4969 13 intestinal intestinal JJ cord-022526-j9kg00qf 4969 14 obstructive obstructive JJ cord-022526-j9kg00qf 4969 15 lesions lesion NNS cord-022526-j9kg00qf 4969 16 such such JJ cord-022526-j9kg00qf 4969 17 as as IN cord-022526-j9kg00qf 4969 18 an an DT cord-022526-j9kg00qf 4969 19 ileal ileal JJ cord-022526-j9kg00qf 4969 20 impaction impaction NN cord-022526-j9kg00qf 4969 21 are be VBP cord-022526-j9kg00qf 4969 22 at at IN cord-022526-j9kg00qf 4969 23 greatest great JJS cord-022526-j9kg00qf 4969 24 risk risk NN cord-022526-j9kg00qf 4969 25 . . . cord-022526-j9kg00qf 4970 1 42 42 CD cord-022526-j9kg00qf 4971 1 Recently recently RB cord-022526-j9kg00qf 4971 2 , , , cord-022526-j9kg00qf 4971 3 the the DT cord-022526-j9kg00qf 4971 4 syndrome syndrome NN cord-022526-j9kg00qf 4971 5 of of IN cord-022526-j9kg00qf 4971 6 postoperative postoperative JJ cord-022526-j9kg00qf 4971 7 ileus ileus NN cord-022526-j9kg00qf 4971 8 in in IN cord-022526-j9kg00qf 4971 9 horses horse NNS cord-022526-j9kg00qf 4971 10 has have VBZ cord-022526-j9kg00qf 4971 11 been be VBN cord-022526-j9kg00qf 4971 12 broadened broaden VBN cord-022526-j9kg00qf 4971 13 to to TO cord-022526-j9kg00qf 4971 14 include include VB cord-022526-j9kg00qf 4971 15 those those DT cord-022526-j9kg00qf 4971 16 horses horse NNS cord-022526-j9kg00qf 4971 17 that that WDT cord-022526-j9kg00qf 4971 18 may may MD cord-022526-j9kg00qf 4971 19 have have VB cord-022526-j9kg00qf 4971 20 delayed delay VBN cord-022526-j9kg00qf 4971 21 transit transit NN cord-022526-j9kg00qf 4971 22 of of IN cord-022526-j9kg00qf 4971 23 ingesta ingesta NNP cord-022526-j9kg00qf 4971 24 through through IN cord-022526-j9kg00qf 4971 25 the the DT cord-022526-j9kg00qf 4971 26 large large JJ cord-022526-j9kg00qf 4971 27 intestine intestine NN cord-022526-j9kg00qf 4971 28 following follow VBG cord-022526-j9kg00qf 4971 29 surgery surgery NN cord-022526-j9kg00qf 4971 30 . . . cord-022526-j9kg00qf 4972 1 This this DT cord-022526-j9kg00qf 4972 2 large large JJ cord-022526-j9kg00qf 4972 3 intestinal intestinal JJ cord-022526-j9kg00qf 4972 4 ileus ileus NN cord-022526-j9kg00qf 4972 5 may may MD cord-022526-j9kg00qf 4972 6 follow follow VB cord-022526-j9kg00qf 4972 7 any any DT cord-022526-j9kg00qf 4972 8 type type NN cord-022526-j9kg00qf 4972 9 of of IN cord-022526-j9kg00qf 4972 10 surgery surgery NN cord-022526-j9kg00qf 4972 11 , , , cord-022526-j9kg00qf 4972 12 particularly particularly RB cord-022526-j9kg00qf 4972 13 horses horse NNS cord-022526-j9kg00qf 4972 14 that that WDT cord-022526-j9kg00qf 4972 15 have have VBP cord-022526-j9kg00qf 4972 16 had have VBN cord-022526-j9kg00qf 4972 17 orthopedic orthopedic NN cord-022526-j9kg00qf 4972 18 surgery surgery NN cord-022526-j9kg00qf 4972 19 , , , cord-022526-j9kg00qf 4972 20 and and CC cord-022526-j9kg00qf 4972 21 is be VBZ cord-022526-j9kg00qf 4972 22 characterized characterize VBN cord-022526-j9kg00qf 4972 23 by by IN cord-022526-j9kg00qf 4972 24 reduced reduce VBN cord-022526-j9kg00qf 4972 25 fecal fecal JJ cord-022526-j9kg00qf 4972 26 output output NN cord-022526-j9kg00qf 4972 27 ( ( -LRB- cord-022526-j9kg00qf 4972 28 fewer few JJR cord-022526-j9kg00qf 4972 29 than than IN cord-022526-j9kg00qf 4972 30 three three CD cord-022526-j9kg00qf 4972 31 piles pile NNS cord-022526-j9kg00qf 4972 32 of of IN cord-022526-j9kg00qf 4972 33 manure manure NN cord-022526-j9kg00qf 4972 34 per per IN cord-022526-j9kg00qf 4972 35 day day NN cord-022526-j9kg00qf 4972 36 ) ) -RRB- cord-022526-j9kg00qf 4972 37 rather rather RB cord-022526-j9kg00qf 4972 38 than than IN cord-022526-j9kg00qf 4972 39 excessive excessive JJ cord-022526-j9kg00qf 4972 40 nasogastric nasogastric NN cord-022526-j9kg00qf 4972 41 reflux reflux NN cord-022526-j9kg00qf 4972 42 . . . cord-022526-j9kg00qf 4973 1 62 62 CD cord-022526-j9kg00qf 4974 1 However however RB cord-022526-j9kg00qf 4974 2 , , , cord-022526-j9kg00qf 4974 3 horses horse NNS cord-022526-j9kg00qf 4974 4 with with IN cord-022526-j9kg00qf 4974 5 excessive excessive JJ cord-022526-j9kg00qf 4974 6 nasogastric nasogastric NN cord-022526-j9kg00qf 4974 7 reflux reflux NN cord-022526-j9kg00qf 4974 8 are be VBP cord-022526-j9kg00qf 4974 9 unlikely unlikely JJ cord-022526-j9kg00qf 4974 10 to to TO cord-022526-j9kg00qf 4974 11 have have VB cord-022526-j9kg00qf 4974 12 normal normal JJ cord-022526-j9kg00qf 4974 13 fecal fecal JJ cord-022526-j9kg00qf 4974 14 output output NN cord-022526-j9kg00qf 4974 15 , , , cord-022526-j9kg00qf 4974 16 so so IN cord-022526-j9kg00qf 4974 17 the the DT cord-022526-j9kg00qf 4974 18 distinction distinction NN cord-022526-j9kg00qf 4974 19 between between IN cord-022526-j9kg00qf 4974 20 these these DT cord-022526-j9kg00qf 4974 21 two two CD cord-022526-j9kg00qf 4974 22 manifestations manifestation NNS cord-022526-j9kg00qf 4974 23 of of IN cord-022526-j9kg00qf 4974 24 ileus ileus NN cord-022526-j9kg00qf 4974 25 is be VBZ cord-022526-j9kg00qf 4974 26 not not RB cord-022526-j9kg00qf 4974 27 absolute absolute JJ cord-022526-j9kg00qf 4974 28 . . . cord-022526-j9kg00qf 4975 1 Mechanisms mechanism NNS cord-022526-j9kg00qf 4975 2 involved involve VBN cord-022526-j9kg00qf 4975 3 in in IN cord-022526-j9kg00qf 4975 4 precipitating precipitate VBG cord-022526-j9kg00qf 4975 5 postoperative postoperative JJ cord-022526-j9kg00qf 4975 6 ileus ileus NN cord-022526-j9kg00qf 4975 7 characterized characterize VBN cord-022526-j9kg00qf 4975 8 by by IN cord-022526-j9kg00qf 4975 9 small small JJ cord-022526-j9kg00qf 4975 10 intestinal intestinal JJ cord-022526-j9kg00qf 4975 11 dysfunction dysfunction NN cord-022526-j9kg00qf 4975 12 likely likely RB cord-022526-j9kg00qf 4975 13 involve involve VBP cord-022526-j9kg00qf 4975 14 local local JJ cord-022526-j9kg00qf 4975 15 inflammation inflammation NN cord-022526-j9kg00qf 4975 16 , , , cord-022526-j9kg00qf 4975 17 reduced reduce VBN cord-022526-j9kg00qf 4975 18 coordination coordination NN cord-022526-j9kg00qf 4975 19 of of IN cord-022526-j9kg00qf 4975 20 progressive progressive JJ cord-022526-j9kg00qf 4975 21 motility motility NN cord-022526-j9kg00qf 4975 22 , , , cord-022526-j9kg00qf 4975 23 and and CC cord-022526-j9kg00qf 4975 24 increased increase VBN cord-022526-j9kg00qf 4975 25 sympathetic sympathetic JJ cord-022526-j9kg00qf 4975 26 tone tone NN cord-022526-j9kg00qf 4975 27 . . . cord-022526-j9kg00qf 4976 1 A a DT cord-022526-j9kg00qf 4976 2 recent recent JJ cord-022526-j9kg00qf 4976 3 series series NN cord-022526-j9kg00qf 4976 4 of of IN cord-022526-j9kg00qf 4976 5 studies study NNS cord-022526-j9kg00qf 4976 6 in in IN cord-022526-j9kg00qf 4976 7 the the DT cord-022526-j9kg00qf 4976 8 rat rat NN cord-022526-j9kg00qf 4976 9 has have VBZ cord-022526-j9kg00qf 4976 10 shown show VBN cord-022526-j9kg00qf 4976 11 that that IN cord-022526-j9kg00qf 4976 12 surgical surgical JJ cord-022526-j9kg00qf 4976 13 manipulation manipulation NN cord-022526-j9kg00qf 4976 14 of of IN cord-022526-j9kg00qf 4976 15 intestine intestine NN cord-022526-j9kg00qf 4976 16 results result NNS cord-022526-j9kg00qf 4976 17 in in IN cord-022526-j9kg00qf 4976 18 delayed delay VBN cord-022526-j9kg00qf 4976 19 transit transit NN cord-022526-j9kg00qf 4976 20 time time NN cord-022526-j9kg00qf 4976 21 associated associate VBN cord-022526-j9kg00qf 4976 22 with with IN cord-022526-j9kg00qf 4976 23 infiltration infiltration NN cord-022526-j9kg00qf 4976 24 of of IN cord-022526-j9kg00qf 4976 25 neutrophils neutrophil NNS cord-022526-j9kg00qf 4976 26 into into IN cord-022526-j9kg00qf 4976 27 intestinal intestinal JJ cord-022526-j9kg00qf 4976 28 longitudinal longitudinal JJ cord-022526-j9kg00qf 4976 29 muscle muscle NN cord-022526-j9kg00qf 4976 30 [ [ -LRB- cord-022526-j9kg00qf 4976 31 63 63 CD cord-022526-j9kg00qf 4976 32 ] ] -RRB- cord-022526-j9kg00qf 4976 33 [ [ -LRB- cord-022526-j9kg00qf 4976 34 64 64 CD cord-022526-j9kg00qf 4976 35 ] ] -RRB- cord-022526-j9kg00qf 4976 36 [ [ -LRB- cord-022526-j9kg00qf 4976 37 65 65 CD cord-022526-j9kg00qf 4976 38 ] ] -RRB- cord-022526-j9kg00qf 4976 39 and and CC cord-022526-j9kg00qf 4976 40 upregulation upregulation NN cord-022526-j9kg00qf 4976 41 of of IN cord-022526-j9kg00qf 4976 42 inducible inducible JJ cord-022526-j9kg00qf 4976 43 nitric nitric NN cord-022526-j9kg00qf 4976 44 oxide oxide NN cord-022526-j9kg00qf 4976 45 synthase synthase NN cord-022526-j9kg00qf 4976 46 and and CC cord-022526-j9kg00qf 4976 47 COX-2 COX-2 NNP cord-022526-j9kg00qf 4976 48 . . . cord-022526-j9kg00qf 4977 1 The the DT cord-022526-j9kg00qf 4977 2 mechanisms mechanism NNS cord-022526-j9kg00qf 4977 3 in in IN cord-022526-j9kg00qf 4977 4 the the DT cord-022526-j9kg00qf 4977 5 horse horse NN cord-022526-j9kg00qf 4977 6 may may MD cord-022526-j9kg00qf 4977 7 be be VB cord-022526-j9kg00qf 4977 8 similar similar JJ cord-022526-j9kg00qf 4977 9 in in IN cord-022526-j9kg00qf 4977 10 that that DT cord-022526-j9kg00qf 4977 11 extensive extensive JJ cord-022526-j9kg00qf 4977 12 manipulation manipulation NN cord-022526-j9kg00qf 4977 13 of of IN cord-022526-j9kg00qf 4977 14 the the DT cord-022526-j9kg00qf 4977 15 intestine intestine NN cord-022526-j9kg00qf 4977 16 resulted result VBD cord-022526-j9kg00qf 4977 17 in in IN cord-022526-j9kg00qf 4977 18 abnormal abnormal JJ cord-022526-j9kg00qf 4977 19 intestinal intestinal JJ cord-022526-j9kg00qf 4977 20 motility motility NN cord-022526-j9kg00qf 4977 21 in in IN cord-022526-j9kg00qf 4977 22 ponies pony NNS cord-022526-j9kg00qf 4977 23 , , , cord-022526-j9kg00qf 4977 24 66 66 CD cord-022526-j9kg00qf 4977 25 and and CC cord-022526-j9kg00qf 4977 26 prostanoids prostanoid NNS cord-022526-j9kg00qf 4977 27 and and CC cord-022526-j9kg00qf 4977 28 nitric nitric NN cord-022526-j9kg00qf 4977 29 oxide oxide NN cord-022526-j9kg00qf 4977 30 alter alter VB cord-022526-j9kg00qf 4977 31 or or CC cord-022526-j9kg00qf 4977 32 reduce reduce VB cord-022526-j9kg00qf 4977 33 intestinal intestinal JJ cord-022526-j9kg00qf 4977 34 motility motility NN cord-022526-j9kg00qf 4977 35 in in IN cord-022526-j9kg00qf 4977 36 horses horse NNS cord-022526-j9kg00qf 4977 37 . . . cord-022526-j9kg00qf 4978 1 [ [ -LRB- cord-022526-j9kg00qf 4978 2 67 67 CD cord-022526-j9kg00qf 4978 3 ] ] -RRB- cord-022526-j9kg00qf 4978 4 [ [ -LRB- cord-022526-j9kg00qf 4978 5 68 68 CD cord-022526-j9kg00qf 4978 6 ] ] -RRB- cord-022526-j9kg00qf 4979 1 [ [ -LRB- cord-022526-j9kg00qf 4979 2 69 69 CD cord-022526-j9kg00qf 4979 3 ] ] -RRB- cord-022526-j9kg00qf 4980 1 Clinical clinical JJ cord-022526-j9kg00qf 4980 2 signs sign NNS cord-022526-j9kg00qf 4980 3 of of IN cord-022526-j9kg00qf 4980 4 postoperative postoperative JJ cord-022526-j9kg00qf 4980 5 ileus ileus NN cord-022526-j9kg00qf 4980 6 following follow VBG cord-022526-j9kg00qf 4980 7 colic colic NN cord-022526-j9kg00qf 4980 8 surgery surgery NN cord-022526-j9kg00qf 4980 9 include include VBP cord-022526-j9kg00qf 4980 10 evidence evidence NN cord-022526-j9kg00qf 4980 11 of of IN cord-022526-j9kg00qf 4980 12 abdominal abdominal JJ cord-022526-j9kg00qf 4980 13 pain pain NN cord-022526-j9kg00qf 4980 14 , , , cord-022526-j9kg00qf 4980 15 increased increase VBN cord-022526-j9kg00qf 4980 16 heart heart NN cord-022526-j9kg00qf 4980 17 rate rate NN cord-022526-j9kg00qf 4980 18 , , , cord-022526-j9kg00qf 4980 19 reduced reduce VBN cord-022526-j9kg00qf 4980 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4980 21 sounds sound NNS cord-022526-j9kg00qf 4980 22 , , , cord-022526-j9kg00qf 4980 23 and and CC cord-022526-j9kg00qf 4980 24 reflux reflux NN cord-022526-j9kg00qf 4980 25 of of IN cord-022526-j9kg00qf 4980 26 gastric gastric JJ cord-022526-j9kg00qf 4980 27 fluid fluid NN cord-022526-j9kg00qf 4980 28 via via IN cord-022526-j9kg00qf 4980 29 a a DT cord-022526-j9kg00qf 4980 30 nasogastric nasogastric NN cord-022526-j9kg00qf 4980 31 tube tube NN cord-022526-j9kg00qf 4980 32 . . . cord-022526-j9kg00qf 4981 1 Of of IN cord-022526-j9kg00qf 4981 2 these these DT cord-022526-j9kg00qf 4981 3 signs sign NNS cord-022526-j9kg00qf 4981 4 , , , cord-022526-j9kg00qf 4981 5 heart heart NN cord-022526-j9kg00qf 4981 6 rate rate NN cord-022526-j9kg00qf 4981 7 is be VBZ cord-022526-j9kg00qf 4981 8 critical critical JJ cord-022526-j9kg00qf 4981 9 because because IN cord-022526-j9kg00qf 4981 10 it -PRON- PRP cord-022526-j9kg00qf 4981 11 appears appear VBZ cord-022526-j9kg00qf 4981 12 to to TO cord-022526-j9kg00qf 4981 13 be be VB cord-022526-j9kg00qf 4981 14 a a DT cord-022526-j9kg00qf 4981 15 more more RBR cord-022526-j9kg00qf 4981 16 sensitive sensitive JJ cord-022526-j9kg00qf 4981 17 indicator indicator NN cord-022526-j9kg00qf 4981 18 of of IN cord-022526-j9kg00qf 4981 19 pain pain NN cord-022526-j9kg00qf 4981 20 in in IN cord-022526-j9kg00qf 4981 21 the the DT cord-022526-j9kg00qf 4981 22 postoperative postoperative JJ cord-022526-j9kg00qf 4981 23 period period NN cord-022526-j9kg00qf 4981 24 than than IN cord-022526-j9kg00qf 4981 25 overt overt JJ cord-022526-j9kg00qf 4981 26 evidence evidence NN cord-022526-j9kg00qf 4981 27 of of IN cord-022526-j9kg00qf 4981 28 colic colic NN cord-022526-j9kg00qf 4981 29 . . . cord-022526-j9kg00qf 4982 1 Therefore therefore RB cord-022526-j9kg00qf 4982 2 a a DT cord-022526-j9kg00qf 4982 3 sudden sudden JJ cord-022526-j9kg00qf 4982 4 increase increase NN cord-022526-j9kg00qf 4982 5 in in IN cord-022526-j9kg00qf 4982 6 the the DT cord-022526-j9kg00qf 4982 7 heart heart NN cord-022526-j9kg00qf 4982 8 rate rate NN cord-022526-j9kg00qf 4982 9 of of IN cord-022526-j9kg00qf 4982 10 a a DT cord-022526-j9kg00qf 4982 11 postoperative postoperative JJ cord-022526-j9kg00qf 4982 12 patient patient NN cord-022526-j9kg00qf 4982 13 following follow VBG cord-022526-j9kg00qf 4982 14 colic colic NN cord-022526-j9kg00qf 4982 15 a a DT cord-022526-j9kg00qf 4982 16 significantly significantly RB cord-022526-j9kg00qf 4982 17 reduced reduce VBN cord-022526-j9kg00qf 4982 18 duration duration NN cord-022526-j9kg00qf 4982 19 of of IN cord-022526-j9kg00qf 4982 20 reflux reflux NN cord-022526-j9kg00qf 4982 21 and and CC cord-022526-j9kg00qf 4982 22 shorter short JJR cord-022526-j9kg00qf 4982 23 postoperative postoperative JJ cord-022526-j9kg00qf 4982 24 hospital hospital NN cord-022526-j9kg00qf 4982 25 stays stay VBZ cord-022526-j9kg00qf 4982 26 compared compare VBN cord-022526-j9kg00qf 4982 27 with with IN cord-022526-j9kg00qf 4982 28 horses horse NNS cord-022526-j9kg00qf 4982 29 not not RB cord-022526-j9kg00qf 4982 30 receiving receive VBG cord-022526-j9kg00qf 4982 31 this this DT cord-022526-j9kg00qf 4982 32 drug drug NN cord-022526-j9kg00qf 4982 33 . . . cord-022526-j9kg00qf 4983 1 76 76 CD cord-022526-j9kg00qf 4984 1 In in IN cord-022526-j9kg00qf 4984 2 the the DT cord-022526-j9kg00qf 4984 3 same same JJ cord-022526-j9kg00qf 4984 4 study study NN cord-022526-j9kg00qf 4984 5 , , , cord-022526-j9kg00qf 4984 6 constant constant JJ cord-022526-j9kg00qf 4984 7 infusion infusion NN cord-022526-j9kg00qf 4984 8 of of IN cord-022526-j9kg00qf 4984 9 metoclopramide metoclopramide NN cord-022526-j9kg00qf 4984 10 was be VBD cord-022526-j9kg00qf 4984 11 superior superior JJ cord-022526-j9kg00qf 4984 12 to to IN cord-022526-j9kg00qf 4984 13 intermittent intermittent JJ cord-022526-j9kg00qf 4984 14 infusion infusion NN cord-022526-j9kg00qf 4984 15 . . . cord-022526-j9kg00qf 4985 1 Recent recent JJ cord-022526-j9kg00qf 4985 2 in in IN cord-022526-j9kg00qf 4985 3 vitro vitro FW cord-022526-j9kg00qf 4985 4 studies study NNS cord-022526-j9kg00qf 4985 5 indicate indicate VBP cord-022526-j9kg00qf 4985 6 that that IN cord-022526-j9kg00qf 4985 7 metoclopramide metoclopramide NN cord-022526-j9kg00qf 4985 8 effectively effectively RB cord-022526-j9kg00qf 4985 9 increases increase VBZ cord-022526-j9kg00qf 4985 10 smooth smooth JJ cord-022526-j9kg00qf 4985 11 muscle muscle NN cord-022526-j9kg00qf 4985 12 contractile contractile JJ cord-022526-j9kg00qf 4985 13 activity activity NN cord-022526-j9kg00qf 4985 14 throughout throughout IN cord-022526-j9kg00qf 4985 15 the the DT cord-022526-j9kg00qf 4985 16 small small JJ cord-022526-j9kg00qf 4985 17 intestine intestine NN cord-022526-j9kg00qf 4985 18 . . . cord-022526-j9kg00qf 4986 1 Similarly similarly RB cord-022526-j9kg00qf 4986 2 , , , cord-022526-j9kg00qf 4986 3 the the DT cord-022526-j9kg00qf 4986 4 motilin motilin NNP cord-022526-j9kg00qf 4986 5 agonist agonist NN cord-022526-j9kg00qf 4986 6 erythromycin erythromycin NNP cord-022526-j9kg00qf 4986 7 had have VBD cord-022526-j9kg00qf 4986 8 stimulatory stimulatory JJ cord-022526-j9kg00qf 4986 9 effects effect NNS cord-022526-j9kg00qf 4986 10 on on IN cord-022526-j9kg00qf 4986 11 equine equine JJ cord-022526-j9kg00qf 4986 12 small small JJ cord-022526-j9kg00qf 4986 13 intestine intestine NN cord-022526-j9kg00qf 4986 14 , , , cord-022526-j9kg00qf 4986 15 although although IN cord-022526-j9kg00qf 4986 16 the the DT cord-022526-j9kg00qf 4986 17 results result NNS cord-022526-j9kg00qf 4986 18 were be VBD cord-022526-j9kg00qf 4986 19 not not RB cord-022526-j9kg00qf 4986 20 uniform uniform JJ cord-022526-j9kg00qf 4986 21 throughout throughout IN cord-022526-j9kg00qf 4986 22 the the DT cord-022526-j9kg00qf 4986 23 small small JJ cord-022526-j9kg00qf 4986 24 intestine intestine NN cord-022526-j9kg00qf 4986 25 . . . cord-022526-j9kg00qf 4987 1 Erythromycin erythromycin NN cord-022526-j9kg00qf 4987 2 stimulates stimulate VBZ cord-022526-j9kg00qf 4987 3 contractile contractile JJ cord-022526-j9kg00qf 4987 4 activity activity NN cord-022526-j9kg00qf 4987 5 in in IN cord-022526-j9kg00qf 4987 6 the the DT cord-022526-j9kg00qf 4987 7 longitudinal longitudinal JJ cord-022526-j9kg00qf 4987 8 muscle muscle NN cord-022526-j9kg00qf 4987 9 of of IN cord-022526-j9kg00qf 4987 10 the the DT cord-022526-j9kg00qf 4987 11 pyloric pyloric JJ cord-022526-j9kg00qf 4987 12 antrum antrum NN cord-022526-j9kg00qf 4987 13 but but CC cord-022526-j9kg00qf 4987 14 inhibits inhibit VBZ cord-022526-j9kg00qf 4987 15 contractile contractile JJ cord-022526-j9kg00qf 4987 16 activity activity NN cord-022526-j9kg00qf 4987 17 in in IN cord-022526-j9kg00qf 4987 18 circular circular JJ cord-022526-j9kg00qf 4987 19 smooth smooth JJ cord-022526-j9kg00qf 4987 20 muscle muscle NN cord-022526-j9kg00qf 4987 21 in in IN cord-022526-j9kg00qf 4987 22 this this DT cord-022526-j9kg00qf 4987 23 segment segment NN cord-022526-j9kg00qf 4987 24 of of IN cord-022526-j9kg00qf 4987 25 the the DT cord-022526-j9kg00qf 4987 26 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4987 27 tract tract NN cord-022526-j9kg00qf 4987 28 . . . cord-022526-j9kg00qf 4988 1 75 75 CD cord-022526-j9kg00qf 4989 1 The the DT cord-022526-j9kg00qf 4989 2 latter latter JJ cord-022526-j9kg00qf 4989 3 may may MD cord-022526-j9kg00qf 4989 4 be be VB cord-022526-j9kg00qf 4989 5 attributable attributable JJ cord-022526-j9kg00qf 4989 6 to to IN cord-022526-j9kg00qf 4989 7 activation activation NN cord-022526-j9kg00qf 4989 8 of of IN cord-022526-j9kg00qf 4989 9 motilin motilin NN cord-022526-j9kg00qf 4989 10 receptors receptor NNS cord-022526-j9kg00qf 4989 11 on on IN cord-022526-j9kg00qf 4989 12 inhibitory inhibitory JJ cord-022526-j9kg00qf 4989 13 nerves nerve NNS cord-022526-j9kg00qf 4989 14 and and CC cord-022526-j9kg00qf 4989 15 may may MD cord-022526-j9kg00qf 4989 16 result result VB cord-022526-j9kg00qf 4989 17 in in IN cord-022526-j9kg00qf 4989 18 enhanced enhanced JJ cord-022526-j9kg00qf 4989 19 gastric gastric JJ cord-022526-j9kg00qf 4989 20 emptying emptying NN cord-022526-j9kg00qf 4989 21 . . . cord-022526-j9kg00qf 4990 1 In in IN cord-022526-j9kg00qf 4990 2 vivo vivo NNP cord-022526-j9kg00qf 4990 3 studies study NNS cord-022526-j9kg00qf 4990 4 on on IN cord-022526-j9kg00qf 4990 5 erythromycin erythromycin NNP cord-022526-j9kg00qf 4990 6 confirmed confirm VBD cord-022526-j9kg00qf 4990 7 the the DT cord-022526-j9kg00qf 4990 8 stimulatory stimulatory JJ cord-022526-j9kg00qf 4990 9 action action NN cord-022526-j9kg00qf 4990 10 of of IN cord-022526-j9kg00qf 4990 11 this this DT cord-022526-j9kg00qf 4990 12 drug drug NN cord-022526-j9kg00qf 4990 13 on on IN cord-022526-j9kg00qf 4990 14 the the DT cord-022526-j9kg00qf 4990 15 distal distal JJ cord-022526-j9kg00qf 4990 16 small small JJ cord-022526-j9kg00qf 4990 17 intestine intestine NN cord-022526-j9kg00qf 4990 18 and and CC cord-022526-j9kg00qf 4990 19 indicated indicate VBD cord-022526-j9kg00qf 4990 20 this this DT cord-022526-j9kg00qf 4990 21 drug drug NN cord-022526-j9kg00qf 4990 22 also also RB cord-022526-j9kg00qf 4990 23 stimulates stimulate VBZ cord-022526-j9kg00qf 4990 24 contractile contractile JJ cord-022526-j9kg00qf 4990 25 activity activity NN cord-022526-j9kg00qf 4990 26 in in IN cord-022526-j9kg00qf 4990 27 the the DT cord-022526-j9kg00qf 4990 28 cecum cecum NN cord-022526-j9kg00qf 4990 29 and and CC cord-022526-j9kg00qf 4990 30 pelvic pelvic JJ cord-022526-j9kg00qf 4990 31 flexure flexure NN cord-022526-j9kg00qf 4990 32 . . . cord-022526-j9kg00qf 4991 1 However however RB cord-022526-j9kg00qf 4991 2 , , , cord-022526-j9kg00qf 4991 3 the the DT cord-022526-j9kg00qf 4991 4 stimulation stimulation NN cord-022526-j9kg00qf 4991 5 depends depend VBZ cord-022526-j9kg00qf 4991 6 on on IN cord-022526-j9kg00qf 4991 7 the the DT cord-022526-j9kg00qf 4991 8 temporal temporal JJ cord-022526-j9kg00qf 4991 9 association association NN cord-022526-j9kg00qf 4991 10 with with IN cord-022526-j9kg00qf 4991 11 surgery surgery NN cord-022526-j9kg00qf 4991 12 . . . cord-022526-j9kg00qf 4992 1 Erythromycin erythromycin NN cord-022526-j9kg00qf 4992 2 stimulated stimulate VBD cord-022526-j9kg00qf 4992 3 contractile contractile JJ cord-022526-j9kg00qf 4992 4 activity activity NN cord-022526-j9kg00qf 4992 5 in in IN cord-022526-j9kg00qf 4992 6 the the DT cord-022526-j9kg00qf 4992 7 postoperative postoperative JJ cord-022526-j9kg00qf 4992 8 period period NN cord-022526-j9kg00qf 4992 9 in in IN cord-022526-j9kg00qf 4992 10 the the DT cord-022526-j9kg00qf 4992 11 ileum ileum NN cord-022526-j9kg00qf 4992 12 and and CC cord-022526-j9kg00qf 4992 13 pelvic pelvic JJ cord-022526-j9kg00qf 4992 14 flexure flexure NN cord-022526-j9kg00qf 4992 15 but but CC cord-022526-j9kg00qf 4992 16 not not RB cord-022526-j9kg00qf 4992 17 the the DT cord-022526-j9kg00qf 4992 18 cecum cecum NN cord-022526-j9kg00qf 4992 19 , , , cord-022526-j9kg00qf 4992 20 78 78 CD cord-022526-j9kg00qf 4992 21 suggesting suggest VBG cord-022526-j9kg00qf 4992 22 this this DT cord-022526-j9kg00qf 4992 23 drug drug NN cord-022526-j9kg00qf 4992 24 may may MD cord-022526-j9kg00qf 4992 25 be be VB cord-022526-j9kg00qf 4992 26 useful useful JJ cord-022526-j9kg00qf 4992 27 for for IN cord-022526-j9kg00qf 4992 28 treating treat VBG cord-022526-j9kg00qf 4992 29 select select JJ cord-022526-j9kg00qf 4992 30 cases case NNS cord-022526-j9kg00qf 4992 31 of of IN cord-022526-j9kg00qf 4992 32 postoperative postoperative JJ cord-022526-j9kg00qf 4992 33 ileus ileus NN cord-022526-j9kg00qf 4992 34 . . . cord-022526-j9kg00qf 4993 1 For for IN cord-022526-j9kg00qf 4993 2 horses horse NNS cord-022526-j9kg00qf 4993 3 with with IN cord-022526-j9kg00qf 4993 4 presumed presume VBN cord-022526-j9kg00qf 4993 5 ileus ileus NN cord-022526-j9kg00qf 4993 6 of of IN cord-022526-j9kg00qf 4993 7 the the DT cord-022526-j9kg00qf 4993 8 large large JJ cord-022526-j9kg00qf 4993 9 colon colon NN cord-022526-j9kg00qf 4993 10 , , , cord-022526-j9kg00qf 4993 11 signs sign NNS cord-022526-j9kg00qf 4993 12 included include VBD cord-022526-j9kg00qf 4993 13 reduced reduce VBN cord-022526-j9kg00qf 4993 14 fecal fecal JJ cord-022526-j9kg00qf 4993 15 output output NN cord-022526-j9kg00qf 4993 16 ( ( -LRB- cord-022526-j9kg00qf 4993 17 fewer few JJR cord-022526-j9kg00qf 4993 18 than than IN cord-022526-j9kg00qf 4993 19 three three CD cord-022526-j9kg00qf 4993 20 piles pile NNS cord-022526-j9kg00qf 4993 21 of of IN cord-022526-j9kg00qf 4993 22 manure manure NN cord-022526-j9kg00qf 4993 23 per per IN cord-022526-j9kg00qf 4993 24 day day NN cord-022526-j9kg00qf 4993 25 ) ) -RRB- cord-022526-j9kg00qf 4993 26 , , , cord-022526-j9kg00qf 4993 27 reduced reduce VBN cord-022526-j9kg00qf 4993 28 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 4993 29 sounds sound NNS cord-022526-j9kg00qf 4993 30 , , , cord-022526-j9kg00qf 4993 31 variable variable JJ cord-022526-j9kg00qf 4993 32 presence presence NN cord-022526-j9kg00qf 4993 33 of of IN cord-022526-j9kg00qf 4993 34 colic colic NN cord-022526-j9kg00qf 4993 35 , , , cord-022526-j9kg00qf 4993 36 and and CC cord-022526-j9kg00qf 4993 37 on on IN cord-022526-j9kg00qf 4993 38 occasion occasion NN cord-022526-j9kg00qf 4993 39 a a DT cord-022526-j9kg00qf 4993 40 palpable palpable JJ cord-022526-j9kg00qf 4993 41 impaction impaction NN cord-022526-j9kg00qf 4993 42 of of IN cord-022526-j9kg00qf 4993 43 the the DT cord-022526-j9kg00qf 4993 44 cecum cecum NN cord-022526-j9kg00qf 4993 45 or or CC cord-022526-j9kg00qf 4993 46 large large JJ cord-022526-j9kg00qf 4993 47 colon colon NN cord-022526-j9kg00qf 4993 48 . . . cord-022526-j9kg00qf 4994 1 Risk risk NN cord-022526-j9kg00qf 4994 2 factors factor NNS cord-022526-j9kg00qf 4994 3 for for IN cord-022526-j9kg00qf 4994 4 this this DT cord-022526-j9kg00qf 4994 5 syndrome syndrome NN cord-022526-j9kg00qf 4994 6 include include VBP cord-022526-j9kg00qf 4994 7 orthopedic orthopedic NN cord-022526-j9kg00qf 4994 8 surgery surgery NN cord-022526-j9kg00qf 4994 9 , , , cord-022526-j9kg00qf 4994 10 length length NN cord-022526-j9kg00qf 4994 11 of of IN cord-022526-j9kg00qf 4994 12 the the DT cord-022526-j9kg00qf 4994 13 operative operative JJ cord-022526-j9kg00qf 4994 14 period period NN cord-022526-j9kg00qf 4994 15 , , , cord-022526-j9kg00qf 4994 16 and and CC cord-022526-j9kg00qf 4994 17 most most RBS cord-022526-j9kg00qf 4994 18 importantly importantly RB cord-022526-j9kg00qf 4994 19 inadequate inadequate JJ cord-022526-j9kg00qf 4994 20 treatment treatment NN cord-022526-j9kg00qf 4994 21 with with IN cord-022526-j9kg00qf 4994 22 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 4994 23 , , , cord-022526-j9kg00qf 4994 24 presumably presumably RB cord-022526-j9kg00qf 4994 25 resulting result VBG cord-022526-j9kg00qf 4994 26 from from IN cord-022526-j9kg00qf 4994 27 insufficient insufficient JJ cord-022526-j9kg00qf 4994 28 control control NN cord-022526-j9kg00qf 4994 29 of of IN cord-022526-j9kg00qf 4994 30 postoperative postoperative JJ cord-022526-j9kg00qf 4994 31 pain pain NN cord-022526-j9kg00qf 4994 32 . . . cord-022526-j9kg00qf 4995 1 Although although IN cord-022526-j9kg00qf 4995 2 treatment treatment NN cord-022526-j9kg00qf 4995 3 of of IN cord-022526-j9kg00qf 4995 4 large large JJ cord-022526-j9kg00qf 4995 5 colon colon NN cord-022526-j9kg00qf 4995 6 impaction impaction NN cord-022526-j9kg00qf 4995 7 in in IN cord-022526-j9kg00qf 4995 8 the the DT cord-022526-j9kg00qf 4995 9 postoperative postoperative JJ cord-022526-j9kg00qf 4995 10 period period NN cord-022526-j9kg00qf 4995 11 typically typically RB cord-022526-j9kg00qf 4995 12 is be VBZ cord-022526-j9kg00qf 4995 13 uncomplicated uncomplicated JJ cord-022526-j9kg00qf 4995 14 , , , cord-022526-j9kg00qf 4995 15 onset onset NN cord-022526-j9kg00qf 4995 16 of of IN cord-022526-j9kg00qf 4995 17 cecal cecal JJ cord-022526-j9kg00qf 4995 18 impaction impaction NN cord-022526-j9kg00qf 4995 19 is be VBZ cord-022526-j9kg00qf 4995 20 fatal fatal JJ cord-022526-j9kg00qf 4995 21 in in IN cord-022526-j9kg00qf 4995 22 many many JJ cord-022526-j9kg00qf 4995 23 cases case NNS cord-022526-j9kg00qf 4995 24 because because IN cord-022526-j9kg00qf 4995 25 of of IN cord-022526-j9kg00qf 4995 26 the the DT cord-022526-j9kg00qf 4995 27 difficulty difficulty NN cord-022526-j9kg00qf 4995 28 in in IN cord-022526-j9kg00qf 4995 29 recognizing recognize VBG cord-022526-j9kg00qf 4995 30 horses horse NNS cord-022526-j9kg00qf 4995 31 that that WDT cord-022526-j9kg00qf 4995 32 have have VBP cord-022526-j9kg00qf 4995 33 cecal cecal JJ cord-022526-j9kg00qf 4995 34 dysfunction dysfunction NN cord-022526-j9kg00qf 4995 35 . . . cord-022526-j9kg00qf 4996 1 Therefore therefore RB cord-022526-j9kg00qf 4996 2 one one PRP cord-022526-j9kg00qf 4996 3 should should MD cord-022526-j9kg00qf 4996 4 pay pay VB cord-022526-j9kg00qf 4996 5 close close JJ cord-022526-j9kg00qf 4996 6 attention attention NN cord-022526-j9kg00qf 4996 7 to to IN cord-022526-j9kg00qf 4996 8 fecal fecal JJ cord-022526-j9kg00qf 4996 9 production production NN cord-022526-j9kg00qf 4996 10 and and CC cord-022526-j9kg00qf 4996 11 optimal optimal JJ cord-022526-j9kg00qf 4996 12 analgesic analgesic JJ cord-022526-j9kg00qf 4996 13 treatment treatment NN cord-022526-j9kg00qf 4996 14 in in IN cord-022526-j9kg00qf 4996 15 any any DT cord-022526-j9kg00qf 4996 16 horse horse NN cord-022526-j9kg00qf 4996 17 following follow VBG cord-022526-j9kg00qf 4996 18 an an DT cord-022526-j9kg00qf 4996 19 orthopedic orthopedic JJ cord-022526-j9kg00qf 4996 20 procedure procedure NN cord-022526-j9kg00qf 4996 21 . . . cord-022526-j9kg00qf 4997 1 62 62 CD cord-022526-j9kg00qf 4998 1 Other other JJ cord-022526-j9kg00qf 4998 2 painful painful JJ cord-022526-j9kg00qf 4998 3 procedures procedure NNS cord-022526-j9kg00qf 4998 4 , , , cord-022526-j9kg00qf 4998 5 including include VBG cord-022526-j9kg00qf 4998 6 ophthalmologic ophthalmologic JJ cord-022526-j9kg00qf 4998 7 procedures procedure NNS cord-022526-j9kg00qf 4998 8 , , , cord-022526-j9kg00qf 4998 9 also also RB cord-022526-j9kg00qf 4998 10 likely likely JJ cord-022526-j9kg00qf 4998 11 place place NN cord-022526-j9kg00qf 4998 12 horses horse NNS cord-022526-j9kg00qf 4998 13 at at IN cord-022526-j9kg00qf 4998 14 risk risk NN cord-022526-j9kg00qf 4998 15 of of IN cord-022526-j9kg00qf 4998 16 developing develop VBG cord-022526-j9kg00qf 4998 17 ileus ileus NN cord-022526-j9kg00qf 4998 18 of of IN cord-022526-j9kg00qf 4998 19 the the DT cord-022526-j9kg00qf 4998 20 large large JJ cord-022526-j9kg00qf 4998 21 intestine intestine NN cord-022526-j9kg00qf 4998 22 . . . cord-022526-j9kg00qf 4999 1 Simple simple JJ cord-022526-j9kg00qf 4999 2 obstructions obstruction NNS cord-022526-j9kg00qf 4999 3 of of IN cord-022526-j9kg00qf 4999 4 the the DT cord-022526-j9kg00qf 4999 5 large large JJ cord-022526-j9kg00qf 4999 6 intestine intestine NN cord-022526-j9kg00qf 4999 7 such such JJ cord-022526-j9kg00qf 4999 8 as as IN cord-022526-j9kg00qf 4999 9 impaction impaction NN cord-022526-j9kg00qf 4999 10 tend tend VB cord-022526-j9kg00qf 4999 11 to to TO cord-022526-j9kg00qf 4999 12 have have VB cord-022526-j9kg00qf 4999 13 a a DT cord-022526-j9kg00qf 4999 14 more more RBR cord-022526-j9kg00qf 4999 15 gradual gradual JJ cord-022526-j9kg00qf 4999 16 onset onset NN cord-022526-j9kg00qf 4999 17 than than IN cord-022526-j9kg00qf 4999 18 those those DT cord-022526-j9kg00qf 4999 19 of of IN cord-022526-j9kg00qf 4999 20 the the DT cord-022526-j9kg00qf 4999 21 small small JJ cord-022526-j9kg00qf 4999 22 intestine intestine NN cord-022526-j9kg00qf 4999 23 , , , cord-022526-j9kg00qf 4999 24 although although IN cord-022526-j9kg00qf 4999 25 horses horse NNS cord-022526-j9kg00qf 4999 26 may may MD cord-022526-j9kg00qf 4999 27 become become VB cord-022526-j9kg00qf 4999 28 acutely acutely RB cord-022526-j9kg00qf 4999 29 and and CC cord-022526-j9kg00qf 4999 30 severely severely RB cord-022526-j9kg00qf 4999 31 painful painful JJ cord-022526-j9kg00qf 4999 32 with with IN cord-022526-j9kg00qf 4999 33 some some DT cord-022526-j9kg00qf 4999 34 forms form NNS cord-022526-j9kg00qf 4999 35 of of IN cord-022526-j9kg00qf 4999 36 colon colon NN cord-022526-j9kg00qf 4999 37 displacement displacement NN cord-022526-j9kg00qf 4999 38 . . . cord-022526-j9kg00qf 5000 1 In in IN cord-022526-j9kg00qf 5000 2 fact fact NN cord-022526-j9kg00qf 5000 3 , , , cord-022526-j9kg00qf 5000 4 some some DT cord-022526-j9kg00qf 5000 5 of of IN cord-022526-j9kg00qf 5000 6 these these DT cord-022526-j9kg00qf 5000 7 cases case NNS cord-022526-j9kg00qf 5000 8 mimic mimic VBP cord-022526-j9kg00qf 5000 9 and and CC cord-022526-j9kg00qf 5000 10 may may MD cord-022526-j9kg00qf 5000 11 progress progress VB cord-022526-j9kg00qf 5000 12 toward toward IN cord-022526-j9kg00qf 5000 13 large large JJ cord-022526-j9kg00qf 5000 14 colon colon NN cord-022526-j9kg00qf 5000 15 volvulus volvulus NN cord-022526-j9kg00qf 5000 16 . . . cord-022526-j9kg00qf 5001 1 Medical medical JJ cord-022526-j9kg00qf 5001 2 therapy therapy NN cord-022526-j9kg00qf 5001 3 is be VBZ cord-022526-j9kg00qf 5001 4 frequently frequently RB cord-022526-j9kg00qf 5001 5 successful successful JJ cord-022526-j9kg00qf 5001 6 in in IN cord-022526-j9kg00qf 5001 7 correcting correct VBG cord-022526-j9kg00qf 5001 8 large large JJ cord-022526-j9kg00qf 5001 9 colon colon NN cord-022526-j9kg00qf 5001 10 impactions impaction NNS cord-022526-j9kg00qf 5001 11 . . . cord-022526-j9kg00qf 5002 1 However however RB cord-022526-j9kg00qf 5002 2 , , , cord-022526-j9kg00qf 5002 3 cecal cecal JJ cord-022526-j9kg00qf 5002 4 impactions impaction NNS cord-022526-j9kg00qf 5002 5 present present VBP cord-022526-j9kg00qf 5002 6 much much RB cord-022526-j9kg00qf 5002 7 more more JJR cord-022526-j9kg00qf 5002 8 of of IN cord-022526-j9kg00qf 5002 9 a a DT cord-022526-j9kg00qf 5002 10 dilemma dilemma NN cord-022526-j9kg00qf 5002 11 because because IN cord-022526-j9kg00qf 5002 12 of of IN cord-022526-j9kg00qf 5002 13 the the DT cord-022526-j9kg00qf 5002 14 greater great JJR cord-022526-j9kg00qf 5002 15 propensity propensity NN cord-022526-j9kg00qf 5002 16 of of IN cord-022526-j9kg00qf 5002 17 this this DT cord-022526-j9kg00qf 5002 18 organ organ NN cord-022526-j9kg00qf 5002 19 to to IN cord-022526-j9kg00qf 5002 20 rupture rupture NN cord-022526-j9kg00qf 5002 21 , , , cord-022526-j9kg00qf 5002 22 the the DT cord-022526-j9kg00qf 5002 23 relative relative JJ cord-022526-j9kg00qf 5002 24 difficulty difficulty NN cord-022526-j9kg00qf 5002 25 of of IN cord-022526-j9kg00qf 5002 26 surgically surgically RB cord-022526-j9kg00qf 5002 27 manipulating manipulate VBG cord-022526-j9kg00qf 5002 28 the the DT cord-022526-j9kg00qf 5002 29 cecum cecum NN cord-022526-j9kg00qf 5002 30 , , , cord-022526-j9kg00qf 5002 31 and and CC cord-022526-j9kg00qf 5002 32 the the DT cord-022526-j9kg00qf 5002 33 onset onset NN cord-022526-j9kg00qf 5002 34 of of IN cord-022526-j9kg00qf 5002 35 cecal cecal JJ cord-022526-j9kg00qf 5002 36 dysfunction dysfunction NN cord-022526-j9kg00qf 5002 37 that that WDT cord-022526-j9kg00qf 5002 38 may may MD cord-022526-j9kg00qf 5002 39 prevent prevent VB cord-022526-j9kg00qf 5002 40 the the DT cord-022526-j9kg00qf 5002 41 cecum cecum NN cord-022526-j9kg00qf 5002 42 from from IN cord-022526-j9kg00qf 5002 43 emptying empty VBG cord-022526-j9kg00qf 5002 44 following follow VBG cord-022526-j9kg00qf 5002 45 surgical surgical JJ cord-022526-j9kg00qf 5002 46 resolution resolution NN cord-022526-j9kg00qf 5002 47 of of IN cord-022526-j9kg00qf 5002 48 impaction impaction NN cord-022526-j9kg00qf 5002 49 . . . cord-022526-j9kg00qf 5003 1 Cecal Cecal NNP cord-022526-j9kg00qf 5003 2 impaction impaction NN cord-022526-j9kg00qf 5003 3 may may MD cord-022526-j9kg00qf 5003 4 be be VB cord-022526-j9kg00qf 5003 5 divided divide VBN cord-022526-j9kg00qf 5003 6 into into IN cord-022526-j9kg00qf 5003 7 two two CD cord-022526-j9kg00qf 5003 8 syndromes syndrome NNS cord-022526-j9kg00qf 5003 9 : : : cord-022526-j9kg00qf 5003 10 primary primary JJ cord-022526-j9kg00qf 5003 11 cecal cecal JJ cord-022526-j9kg00qf 5003 12 impactions impaction NNS cord-022526-j9kg00qf 5003 13 that that WDT cord-022526-j9kg00qf 5003 14 result result VBP cord-022526-j9kg00qf 5003 15 from from IN cord-022526-j9kg00qf 5003 16 excessive excessive JJ cord-022526-j9kg00qf 5003 17 accumulation accumulation NN cord-022526-j9kg00qf 5003 18 of of IN cord-022526-j9kg00qf 5003 19 ingesta ingesta NNP cord-022526-j9kg00qf 5003 20 in in IN cord-022526-j9kg00qf 5003 21 the the DT cord-022526-j9kg00qf 5003 22 cecum cecum NN cord-022526-j9kg00qf 5003 23 and and CC cord-022526-j9kg00qf 5003 24 secondary secondary JJ cord-022526-j9kg00qf 5003 25 cecal cecal JJ cord-022526-j9kg00qf 5003 26 impactions impaction NNS cord-022526-j9kg00qf 5003 27 that that WDT cord-022526-j9kg00qf 5003 28 develop develop VBP cord-022526-j9kg00qf 5003 29 while while IN cord-022526-j9kg00qf 5003 30 a a DT cord-022526-j9kg00qf 5003 31 horse horse NN cord-022526-j9kg00qf 5003 32 is be VBZ cord-022526-j9kg00qf 5003 33 being be VBG cord-022526-j9kg00qf 5003 34 treated treat VBN cord-022526-j9kg00qf 5003 35 for for IN cord-022526-j9kg00qf 5003 36 a a DT cord-022526-j9kg00qf 5003 37 separate separate JJ cord-022526-j9kg00qf 5003 38 problem problem NN cord-022526-j9kg00qf 5003 39 . . . cord-022526-j9kg00qf 5004 1 79 79 CD cord-022526-j9kg00qf 5004 2 , , , cord-022526-j9kg00qf 5004 3 80 80 CD cord-022526-j9kg00qf 5005 1 Although although IN cord-022526-j9kg00qf 5005 2 primary primary JJ cord-022526-j9kg00qf 5005 3 impactions impaction NNS cord-022526-j9kg00qf 5005 4 typically typically RB cord-022526-j9kg00qf 5005 5 consist consist VBP cord-022526-j9kg00qf 5005 6 of of IN cord-022526-j9kg00qf 5005 7 impacted impact VBN cord-022526-j9kg00qf 5005 8 , , , cord-022526-j9kg00qf 5005 9 relatively relatively RB cord-022526-j9kg00qf 5005 10 dry dry JJ cord-022526-j9kg00qf 5005 11 fecal fecal JJ cord-022526-j9kg00qf 5005 12 material material NN cord-022526-j9kg00qf 5005 13 and and CC cord-022526-j9kg00qf 5005 14 secondary secondary JJ cord-022526-j9kg00qf 5005 15 cecal cecal JJ cord-022526-j9kg00qf 5005 16 impactions impaction NNS cord-022526-j9kg00qf 5005 17 tend tend VBP cord-022526-j9kg00qf 5005 18 to to TO cord-022526-j9kg00qf 5005 19 have have VB cord-022526-j9kg00qf 5005 20 fluid fluid JJ cord-022526-j9kg00qf 5005 21 contents content NNS cord-022526-j9kg00qf 5005 22 , , , cord-022526-j9kg00qf 5005 23 considerable considerable JJ cord-022526-j9kg00qf 5005 24 overlap overlap NN cord-022526-j9kg00qf 5005 25 exists exist VBZ cord-022526-j9kg00qf 5005 26 between between IN cord-022526-j9kg00qf 5005 27 the the DT cord-022526-j9kg00qf 5005 28 two two CD cord-022526-j9kg00qf 5005 29 syndromes syndrome NNS cord-022526-j9kg00qf 5005 30 , , , cord-022526-j9kg00qf 5005 31 and and CC cord-022526-j9kg00qf 5005 32 one one PRP cord-022526-j9kg00qf 5005 33 must must MD cord-022526-j9kg00qf 5005 34 approach approach VB cord-022526-j9kg00qf 5005 35 each each DT cord-022526-j9kg00qf 5005 36 case case NN cord-022526-j9kg00qf 5005 37 carefully carefully RB cord-022526-j9kg00qf 5005 38 . . . cord-022526-j9kg00qf 5006 1 In in IN cord-022526-j9kg00qf 5006 2 horses horse NNS cord-022526-j9kg00qf 5006 3 with with IN cord-022526-j9kg00qf 5006 4 primary primary JJ cord-022526-j9kg00qf 5006 5 cecal cecal JJ cord-022526-j9kg00qf 5006 6 impactions impaction NNS cord-022526-j9kg00qf 5006 7 , , , cord-022526-j9kg00qf 5006 8 onset onset NN cord-022526-j9kg00qf 5006 9 of of IN cord-022526-j9kg00qf 5006 10 abdominal abdominal JJ cord-022526-j9kg00qf 5006 11 pain pain NN cord-022526-j9kg00qf 5006 12 occurs occur VBZ cord-022526-j9kg00qf 5006 13 over over IN cord-022526-j9kg00qf 5006 14 a a DT cord-022526-j9kg00qf 5006 15 number number NN cord-022526-j9kg00qf 5006 16 of of IN cord-022526-j9kg00qf 5006 17 days day NNS cord-022526-j9kg00qf 5006 18 , , , cord-022526-j9kg00qf 5006 19 reminiscent reminiscent JJ cord-022526-j9kg00qf 5006 20 of of IN cord-022526-j9kg00qf 5006 21 the the DT cord-022526-j9kg00qf 5006 22 development development NN cord-022526-j9kg00qf 5006 23 of of IN cord-022526-j9kg00qf 5006 24 a a DT cord-022526-j9kg00qf 5006 25 large large JJ cord-022526-j9kg00qf 5006 26 colon colon NN cord-022526-j9kg00qf 5006 27 impaction impaction NN cord-022526-j9kg00qf 5006 28 . . . cord-022526-j9kg00qf 5007 1 One one PRP cord-022526-j9kg00qf 5007 2 should should MD cord-022526-j9kg00qf 5007 3 differentiate differentiate VB cord-022526-j9kg00qf 5007 4 cecal cecal JJ cord-022526-j9kg00qf 5007 5 impactions impaction NNS cord-022526-j9kg00qf 5007 6 from from IN cord-022526-j9kg00qf 5007 7 large large JJ cord-022526-j9kg00qf 5007 8 colon colon NN cord-022526-j9kg00qf 5007 9 impactions impaction NNS cord-022526-j9kg00qf 5007 10 on on IN cord-022526-j9kg00qf 5007 11 the the DT cord-022526-j9kg00qf 5007 12 basis basis NN cord-022526-j9kg00qf 5007 13 of of IN cord-022526-j9kg00qf 5007 14 rectal rectal JJ cord-022526-j9kg00qf 5007 15 palpation palpation NN cord-022526-j9kg00qf 5007 16 findings finding NNS cord-022526-j9kg00qf 5007 17 . . . cord-022526-j9kg00qf 5008 1 Cecal Cecal NNP cord-022526-j9kg00qf 5008 2 impactions impaction NNS cord-022526-j9kg00qf 5008 3 have have VBP cord-022526-j9kg00qf 5008 4 a a DT cord-022526-j9kg00qf 5008 5 propensity propensity NN cord-022526-j9kg00qf 5008 6 to to TO cord-022526-j9kg00qf 5008 7 rupture rupture VB cord-022526-j9kg00qf 5008 8 before before IN cord-022526-j9kg00qf 5008 9 the the DT cord-022526-j9kg00qf 5008 10 development development NN cord-022526-j9kg00qf 5008 11 of of IN cord-022526-j9kg00qf 5008 12 severe severe JJ cord-022526-j9kg00qf 5008 13 abdominal abdominal JJ cord-022526-j9kg00qf 5008 14 pain pain NN cord-022526-j9kg00qf 5008 15 or or CC cord-022526-j9kg00qf 5008 16 systemic systemic JJ cord-022526-j9kg00qf 5008 17 deterioration deterioration NN cord-022526-j9kg00qf 5008 18 and and CC cord-022526-j9kg00qf 5008 19 therefore therefore RB cord-022526-j9kg00qf 5008 20 must must MD cord-022526-j9kg00qf 5008 21 be be VB cord-022526-j9kg00qf 5008 22 monitored monitor VBN cord-022526-j9kg00qf 5008 23 closely closely RB cord-022526-j9kg00qf 5008 24 . . . cord-022526-j9kg00qf 5009 1 79 79 CD cord-022526-j9kg00qf 5009 2 Secondary secondary JJ cord-022526-j9kg00qf 5009 3 cecal cecal JJ cord-022526-j9kg00qf 5009 4 impactions impaction NNS cord-022526-j9kg00qf 5009 5 typically typically RB cord-022526-j9kg00qf 5009 6 develop develop VBP cord-022526-j9kg00qf 5009 7 following follow VBG cord-022526-j9kg00qf 5009 8 unrelated unrelated JJ cord-022526-j9kg00qf 5009 9 surgical surgical JJ cord-022526-j9kg00qf 5009 10 procedures procedure NNS cord-022526-j9kg00qf 5009 11 that that WDT cord-022526-j9kg00qf 5009 12 result result VBP cord-022526-j9kg00qf 5009 13 in in IN cord-022526-j9kg00qf 5009 14 postoperative postoperative JJ cord-022526-j9kg00qf 5009 15 pain pain NN cord-022526-j9kg00qf 5009 16 ( ( -LRB- cord-022526-j9kg00qf 5009 17 particularly particularly RB cord-022526-j9kg00qf 5009 18 orthopedic orthopedic JJ cord-022526-j9kg00qf 5009 19 surgeries surgery NNS cord-022526-j9kg00qf 5009 20 ) ) -RRB- cord-022526-j9kg00qf 5009 21 . . . cord-022526-j9kg00qf 5010 1 Secondary secondary JJ cord-022526-j9kg00qf 5010 2 cecal cecal JJ cord-022526-j9kg00qf 5010 3 impactions impaction NNS cord-022526-j9kg00qf 5010 4 may may MD cord-022526-j9kg00qf 5010 5 be be VB cord-022526-j9kg00qf 5010 6 even even RB cord-022526-j9kg00qf 5010 7 more more RBR cord-022526-j9kg00qf 5010 8 difficult difficult JJ cord-022526-j9kg00qf 5010 9 to to TO cord-022526-j9kg00qf 5010 10 detect detect VB cord-022526-j9kg00qf 5010 11 because because IN cord-022526-j9kg00qf 5010 12 one one PRP cord-022526-j9kg00qf 5010 13 may may MD cord-022526-j9kg00qf 5010 14 attribute attribute VB cord-022526-j9kg00qf 5010 15 postoperative postoperative JJ cord-022526-j9kg00qf 5010 16 depression depression NN cord-022526-j9kg00qf 5010 17 and and CC cord-022526-j9kg00qf 5010 18 decreased decrease VBD cord-022526-j9kg00qf 5010 19 fecal fecal JJ cord-022526-j9kg00qf 5010 20 output output NN cord-022526-j9kg00qf 5010 21 to to IN cord-022526-j9kg00qf 5010 22 the the DT cord-022526-j9kg00qf 5010 23 operative operative JJ cord-022526-j9kg00qf 5010 24 procedure procedure NN cord-022526-j9kg00qf 5010 25 rather rather RB cord-022526-j9kg00qf 5010 26 than than IN cord-022526-j9kg00qf 5010 27 to to IN cord-022526-j9kg00qf 5010 28 colic colic NN cord-022526-j9kg00qf 5010 29 . . . cord-022526-j9kg00qf 5011 1 By by IN cord-022526-j9kg00qf 5011 2 the the DT cord-022526-j9kg00qf 5011 3 time time NN cord-022526-j9kg00qf 5011 4 horses horse NNS cord-022526-j9kg00qf 5011 5 with with IN cord-022526-j9kg00qf 5011 6 secondary secondary JJ cord-022526-j9kg00qf 5011 7 cecal cecal JJ cord-022526-j9kg00qf 5011 8 impactions impaction NNS cord-022526-j9kg00qf 5011 9 show show VBP cord-022526-j9kg00qf 5011 10 noticeable noticeable JJ cord-022526-j9kg00qf 5011 11 signs sign NNS cord-022526-j9kg00qf 5011 12 of of IN cord-022526-j9kg00qf 5011 13 colic colic NN cord-022526-j9kg00qf 5011 14 , , , cord-022526-j9kg00qf 5011 15 the the DT cord-022526-j9kg00qf 5011 16 cecum cecum NN cord-022526-j9kg00qf 5011 17 may may MD cord-022526-j9kg00qf 5011 18 be be VB cord-022526-j9kg00qf 5011 19 close close JJ cord-022526-j9kg00qf 5011 20 to to TO cord-022526-j9kg00qf 5011 21 rupture rupture VB cord-022526-j9kg00qf 5011 22 . . . cord-022526-j9kg00qf 5012 1 In in IN cord-022526-j9kg00qf 5012 2 many many JJ cord-022526-j9kg00qf 5012 3 cases case NNS cord-022526-j9kg00qf 5012 4 , , , cord-022526-j9kg00qf 5012 5 no no DT cord-022526-j9kg00qf 5012 6 signs sign NNS cord-022526-j9kg00qf 5012 7 of of IN cord-022526-j9kg00qf 5012 8 impending impend VBG cord-022526-j9kg00qf 5012 9 rupture rupture NN cord-022526-j9kg00qf 5012 10 are be VBP cord-022526-j9kg00qf 5012 11 evident evident JJ cord-022526-j9kg00qf 5012 12 . . . cord-022526-j9kg00qf 5013 1 80 80 CD cord-022526-j9kg00qf 5014 1 Therefore therefore RB cord-022526-j9kg00qf 5014 2 all all DT cord-022526-j9kg00qf 5014 3 horses horse NNS cord-022526-j9kg00qf 5014 4 that that WDT cord-022526-j9kg00qf 5014 5 undergo undergo VBP cord-022526-j9kg00qf 5014 6 surgeries surgery NNS cord-022526-j9kg00qf 5014 7 in in IN cord-022526-j9kg00qf 5014 8 which which WDT cord-022526-j9kg00qf 5014 9 considerable considerable JJ cord-022526-j9kg00qf 5014 10 postoperative postoperative JJ cord-022526-j9kg00qf 5014 11 pain pain NN cord-022526-j9kg00qf 5014 12 may may MD cord-022526-j9kg00qf 5014 13 develop develop VB cord-022526-j9kg00qf 5014 14 should should MD cord-022526-j9kg00qf 5014 15 have have VB cord-022526-j9kg00qf 5014 16 feed feed NN cord-022526-j9kg00qf 5014 17 intake intake NN cord-022526-j9kg00qf 5014 18 and and CC cord-022526-j9kg00qf 5014 19 manure manure NN cord-022526-j9kg00qf 5014 20 production production NN cord-022526-j9kg00qf 5014 21 closely closely RB cord-022526-j9kg00qf 5014 22 monitored monitor VBD cord-022526-j9kg00qf 5014 23 . . . cord-022526-j9kg00qf 5015 1 A a DT cord-022526-j9kg00qf 5015 2 recent recent JJ cord-022526-j9kg00qf 5015 3 study study NN cord-022526-j9kg00qf 5015 4 indicated indicate VBD cord-022526-j9kg00qf 5015 5 that that IN cord-022526-j9kg00qf 5015 6 horses horse NNS cord-022526-j9kg00qf 5015 7 that that WDT cord-022526-j9kg00qf 5015 8 produce produce VBP cord-022526-j9kg00qf 5015 9 fewer few JJR cord-022526-j9kg00qf 5015 10 than than IN cord-022526-j9kg00qf 5015 11 three three CD cord-022526-j9kg00qf 5015 12 piles pile NNS cord-022526-j9kg00qf 5015 13 of of IN cord-022526-j9kg00qf 5015 14 manure manure NN cord-022526-j9kg00qf 5015 15 daily daily RB cord-022526-j9kg00qf 5015 16 in in IN cord-022526-j9kg00qf 5015 17 the the DT cord-022526-j9kg00qf 5015 18 postoperative postoperative JJ cord-022526-j9kg00qf 5015 19 period period NN cord-022526-j9kg00qf 5015 20 are be VBP cord-022526-j9kg00qf 5015 21 at at IN cord-022526-j9kg00qf 5015 22 risk risk NN cord-022526-j9kg00qf 5015 23 of of IN cord-022526-j9kg00qf 5015 24 developing develop VBG cord-022526-j9kg00qf 5015 25 a a DT cord-022526-j9kg00qf 5015 26 large large JJ cord-022526-j9kg00qf 5015 27 intestinal intestinal JJ cord-022526-j9kg00qf 5015 28 impaction impaction NN cord-022526-j9kg00qf 5015 29 . . . cord-022526-j9kg00qf 5016 1 Furthermore furthermore RB cord-022526-j9kg00qf 5016 2 , , , cord-022526-j9kg00qf 5016 3 horses horse NNS cord-022526-j9kg00qf 5016 4 that that WDT cord-022526-j9kg00qf 5016 5 underwent undergo VBD cord-022526-j9kg00qf 5016 6 prolonged prolonged JJ cord-022526-j9kg00qf 5016 7 ( ( -LRB- cord-022526-j9kg00qf 5016 8 > > NFP cord-022526-j9kg00qf 5016 9 1 1 CD cord-022526-j9kg00qf 5016 10 hour hour NN cord-022526-j9kg00qf 5016 11 ) ) -RRB- cord-022526-j9kg00qf 5016 12 orthopedic orthopedic NN cord-022526-j9kg00qf 5016 13 surgery surgery NN cord-022526-j9kg00qf 5016 14 that that WDT cord-022526-j9kg00qf 5016 15 received receive VBD cord-022526-j9kg00qf 5016 16 inadequate inadequate JJ cord-022526-j9kg00qf 5016 17 treatment treatment NN cord-022526-j9kg00qf 5016 18 with with IN cord-022526-j9kg00qf 5016 19 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 5016 20 were be VBD cord-022526-j9kg00qf 5016 21 at at IN cord-022526-j9kg00qf 5016 22 considerable considerable JJ cord-022526-j9kg00qf 5016 23 risk risk NN cord-022526-j9kg00qf 5016 24 of of IN cord-022526-j9kg00qf 5016 25 reduced reduce VBN cord-022526-j9kg00qf 5016 26 postoperative postoperative JJ cord-022526-j9kg00qf 5016 27 fecal fecal JJ cord-022526-j9kg00qf 5016 28 output output NN cord-022526-j9kg00qf 5016 29 . . . cord-022526-j9kg00qf 5017 1 62 62 CD cord-022526-j9kg00qf 5018 1 These these DT cord-022526-j9kg00qf 5018 2 results result NNS cord-022526-j9kg00qf 5018 3 are be VBP cord-022526-j9kg00qf 5018 4 in in IN cord-022526-j9kg00qf 5018 5 contrast contrast NN cord-022526-j9kg00qf 5018 6 to to IN cord-022526-j9kg00qf 5018 7 statements statement NNS cord-022526-j9kg00qf 5018 8 indicating indicate VBG cord-022526-j9kg00qf 5018 9 that that IN cord-022526-j9kg00qf 5018 10 NSAIDs NSAIDs NNPS cord-022526-j9kg00qf 5018 11 may may MD cord-022526-j9kg00qf 5018 12 place place VB cord-022526-j9kg00qf 5018 13 horses horse NNS cord-022526-j9kg00qf 5018 14 at at IN cord-022526-j9kg00qf 5018 15 risk risk NN cord-022526-j9kg00qf 5018 16 of of IN cord-022526-j9kg00qf 5018 17 impaction impaction NN cord-022526-j9kg00qf 5018 18 , , , cord-022526-j9kg00qf 5018 19 statements statement NNS cord-022526-j9kg00qf 5018 20 that that WDT cord-022526-j9kg00qf 5018 21 appear appear VBP cord-022526-j9kg00qf 5018 22 to to TO cord-022526-j9kg00qf 5018 23 be be VB cord-022526-j9kg00qf 5018 24 based base VBN cord-022526-j9kg00qf 5018 25 largely largely RB cord-022526-j9kg00qf 5018 26 on on IN cord-022526-j9kg00qf 5018 27 clinical clinical JJ cord-022526-j9kg00qf 5018 28 impressions impression NNS cord-022526-j9kg00qf 5018 29 rather rather RB cord-022526-j9kg00qf 5018 30 than than IN cord-022526-j9kg00qf 5018 31 on on IN cord-022526-j9kg00qf 5018 32 risk risk NN cord-022526-j9kg00qf 5018 33 analysis analysis NN cord-022526-j9kg00qf 5018 34 . . . cord-022526-j9kg00qf 5019 1 80 80 CD cord-022526-j9kg00qf 5020 1 The the DT cord-022526-j9kg00qf 5020 2 diagnosis diagnosis NN cord-022526-j9kg00qf 5020 3 of of IN cord-022526-j9kg00qf 5020 4 primary primary JJ cord-022526-j9kg00qf 5020 5 cecal cecal JJ cord-022526-j9kg00qf 5020 6 impaction impaction NN cord-022526-j9kg00qf 5020 7 is be VBZ cord-022526-j9kg00qf 5020 8 based base VBN cord-022526-j9kg00qf 5020 9 on on IN cord-022526-j9kg00qf 5020 10 palpation palpation NN cord-022526-j9kg00qf 5020 11 of of IN cord-022526-j9kg00qf 5020 12 a a DT cord-022526-j9kg00qf 5020 13 firm firm NN cord-022526-j9kg00qf 5020 14 , , , cord-022526-j9kg00qf 5020 15 impacted impact VBN cord-022526-j9kg00qf 5020 16 cecum cecum NN cord-022526-j9kg00qf 5020 17 per per IN cord-022526-j9kg00qf 5020 18 rectum rectum NN cord-022526-j9kg00qf 5020 19 . . . cord-022526-j9kg00qf 5021 1 In in IN cord-022526-j9kg00qf 5021 2 some some DT cord-022526-j9kg00qf 5021 3 cases case NNS cord-022526-j9kg00qf 5021 4 , , , cord-022526-j9kg00qf 5021 5 cecal cecal JJ cord-022526-j9kg00qf 5021 6 impactions impaction NNS cord-022526-j9kg00qf 5021 7 may may MD cord-022526-j9kg00qf 5021 8 be be VB cord-022526-j9kg00qf 5021 9 difficult difficult JJ cord-022526-j9kg00qf 5021 10 to to TO cord-022526-j9kg00qf 5021 11 differentiate differentiate VB cord-022526-j9kg00qf 5021 12 from from IN cord-022526-j9kg00qf 5021 13 large large JJ cord-022526-j9kg00qf 5021 14 colon colon NN cord-022526-j9kg00qf 5021 15 impactions impaction NNS cord-022526-j9kg00qf 5021 16 . . . cord-022526-j9kg00qf 5022 1 However however RB cord-022526-j9kg00qf 5022 2 , , , cord-022526-j9kg00qf 5022 3 careful careful JJ cord-022526-j9kg00qf 5022 4 palpation palpation NN cord-022526-j9kg00qf 5022 5 reveals reveal VBZ cord-022526-j9kg00qf 5022 6 the the DT cord-022526-j9kg00qf 5022 7 inability inability NN cord-022526-j9kg00qf 5022 8 to to TO cord-022526-j9kg00qf 5022 9 move move VB cord-022526-j9kg00qf 5022 10 the the DT cord-022526-j9kg00qf 5022 11 hand hand NN cord-022526-j9kg00qf 5022 12 completely completely RB cord-022526-j9kg00qf 5022 13 dorsal dorsal JJ cord-022526-j9kg00qf 5022 14 to to IN cord-022526-j9kg00qf 5022 15 the the DT cord-022526-j9kg00qf 5022 16 impacted impact VBN cord-022526-j9kg00qf 5022 17 viscus viscus NN cord-022526-j9kg00qf 5022 18 because because IN cord-022526-j9kg00qf 5022 19 of of IN cord-022526-j9kg00qf 5022 20 the the DT cord-022526-j9kg00qf 5022 21 attachment attachment NN cord-022526-j9kg00qf 5022 22 of of IN cord-022526-j9kg00qf 5022 23 the the DT cord-022526-j9kg00qf 5022 24 cecum cecum NN cord-022526-j9kg00qf 5022 25 to to IN cord-022526-j9kg00qf 5022 26 the the DT cord-022526-j9kg00qf 5022 27 dorsal dorsal JJ cord-022526-j9kg00qf 5022 28 body body NN cord-022526-j9kg00qf 5022 29 wall wall NN cord-022526-j9kg00qf 5022 30 . . . cord-022526-j9kg00qf 5023 1 Treatment treatment NN cord-022526-j9kg00qf 5023 2 for for IN cord-022526-j9kg00qf 5023 3 horses horse NNS cord-022526-j9kg00qf 5023 4 with with IN cord-022526-j9kg00qf 5023 5 primary primary JJ cord-022526-j9kg00qf 5023 6 cecal cecal JJ cord-022526-j9kg00qf 5023 7 impactions impaction NNS cord-022526-j9kg00qf 5023 8 may may MD cord-022526-j9kg00qf 5023 9 include include VB cord-022526-j9kg00qf 5023 10 initial initial JJ cord-022526-j9kg00qf 5023 11 medical medical JJ cord-022526-j9kg00qf 5023 12 therapy therapy NN cord-022526-j9kg00qf 5023 13 , , , cord-022526-j9kg00qf 5023 14 including include VBG cord-022526-j9kg00qf 5023 15 aggressive aggressive JJ cord-022526-j9kg00qf 5023 16 administration administration NN cord-022526-j9kg00qf 5023 17 of of IN cord-022526-j9kg00qf 5023 18 intravenous intravenous JJ cord-022526-j9kg00qf 5023 19 fluids fluid NNS cord-022526-j9kg00qf 5023 20 and and CC cord-022526-j9kg00qf 5023 21 judicious judicious JJ cord-022526-j9kg00qf 5023 22 use use NN cord-022526-j9kg00qf 5023 23 of of IN cord-022526-j9kg00qf 5023 24 analgesics analgesic NNS cord-022526-j9kg00qf 5023 25 . . . cord-022526-j9kg00qf 5024 1 80 80 CD cord-022526-j9kg00qf 5025 1 However however RB cord-022526-j9kg00qf 5025 2 , , , cord-022526-j9kg00qf 5025 3 if if IN cord-022526-j9kg00qf 5025 4 the the DT cord-022526-j9kg00qf 5025 5 cecum cecum NN cord-022526-j9kg00qf 5025 6 is be VBZ cord-022526-j9kg00qf 5025 7 distended distend VBN cord-022526-j9kg00qf 5025 8 grossly grossly RB cord-022526-j9kg00qf 5025 9 or or CC cord-022526-j9kg00qf 5025 10 if if IN cord-022526-j9kg00qf 5025 11 medical medical JJ cord-022526-j9kg00qf 5025 12 therapy therapy NN cord-022526-j9kg00qf 5025 13 hasno hasno NN cord-022526-j9kg00qf 5025 14 effect effect NN cord-022526-j9kg00qf 5025 15 within within IN cord-022526-j9kg00qf 5025 16 a a DT cord-022526-j9kg00qf 5025 17 reasonable reasonable JJ cord-022526-j9kg00qf 5025 18 period period NN cord-022526-j9kg00qf 5025 19 of of IN cord-022526-j9kg00qf 5025 20 time time NN cord-022526-j9kg00qf 5025 21 , , , cord-022526-j9kg00qf 5025 22 surgical surgical JJ cord-022526-j9kg00qf 5025 23 evacuation evacuation NN cord-022526-j9kg00qf 5025 24 of of IN cord-022526-j9kg00qf 5025 25 the the DT cord-022526-j9kg00qf 5025 26 cecum cecum NN cord-022526-j9kg00qf 5025 27 via via IN cord-022526-j9kg00qf 5025 28 a a DT cord-022526-j9kg00qf 5025 29 typhlotomy typhlotomy NN cord-022526-j9kg00qf 5025 30 is be VBZ cord-022526-j9kg00qf 5025 31 indicated indicate VBN cord-022526-j9kg00qf 5025 32 . . . cord-022526-j9kg00qf 5026 1 79 79 CD cord-022526-j9kg00qf 5027 1 In in IN cord-022526-j9kg00qf 5027 2 addition addition NN cord-022526-j9kg00qf 5027 3 , , , cord-022526-j9kg00qf 5027 4 performing perform VBG cord-022526-j9kg00qf 5027 5 an an DT cord-022526-j9kg00qf 5027 6 ileocolostomy ileocolostomy NN cord-022526-j9kg00qf 5027 7 to to TO cord-022526-j9kg00qf 5027 8 bypass bypass VB cord-022526-j9kg00qf 5027 9 the the DT cord-022526-j9kg00qf 5027 10 cecum cecum NN cord-022526-j9kg00qf 5027 11 is be VBZ cord-022526-j9kg00qf 5027 12 advisable advisable JJ cord-022526-j9kg00qf 5027 13 , , , cord-022526-j9kg00qf 5027 14 because because IN cord-022526-j9kg00qf 5027 15 postoperative postoperative JJ cord-022526-j9kg00qf 5027 16 cecal cecal JJ cord-022526-j9kg00qf 5027 17 motility motility NN cord-022526-j9kg00qf 5027 18 dysfunction dysfunction NN cord-022526-j9kg00qf 5027 19 with with IN cord-022526-j9kg00qf 5027 20 recurrence recurrence NN cord-022526-j9kg00qf 5027 21 of of IN cord-022526-j9kg00qf 5027 22 the the DT cord-022526-j9kg00qf 5027 23 impaction impaction NN cord-022526-j9kg00qf 5027 24 is be VBZ cord-022526-j9kg00qf 5027 25 common common JJ cord-022526-j9kg00qf 5027 26 . . . cord-022526-j9kg00qf 5028 1 46 46 CD cord-022526-j9kg00qf 5028 2 , , , cord-022526-j9kg00qf 5028 3 81 81 CD cord-022526-j9kg00qf 5029 1 In in IN cord-022526-j9kg00qf 5029 2 horses horse NNS cord-022526-j9kg00qf 5029 3 that that WDT cord-022526-j9kg00qf 5029 4 develop develop VBP cord-022526-j9kg00qf 5029 5 secondary secondary JJ cord-022526-j9kg00qf 5029 6 cecal cecal JJ cord-022526-j9kg00qf 5029 7 impactions impaction NNS cord-022526-j9kg00qf 5029 8 , , , cord-022526-j9kg00qf 5029 9 diagnosis diagnosis NN cord-022526-j9kg00qf 5029 10 is be VBZ cord-022526-j9kg00qf 5029 11 based base VBN cord-022526-j9kg00qf 5029 12 on on IN cord-022526-j9kg00qf 5029 13 palpation palpation NN cord-022526-j9kg00qf 5029 14 of of IN cord-022526-j9kg00qf 5029 15 a a DT cord-022526-j9kg00qf 5029 16 greatly greatly RB cord-022526-j9kg00qf 5029 17 distended distended JJ cord-022526-j9kg00qf 5029 18 cecum cecum NN cord-022526-j9kg00qf 5029 19 filled fill VBN cord-022526-j9kg00qf 5029 20 with with IN cord-022526-j9kg00qf 5029 21 semifluid semifluid JJ cord-022526-j9kg00qf 5029 22 intestinal intestinal JJ cord-022526-j9kg00qf 5029 23 contents content NNS cord-022526-j9kg00qf 5029 24 . . . cord-022526-j9kg00qf 5030 1 The the DT cord-022526-j9kg00qf 5030 2 nature nature NN cord-022526-j9kg00qf 5030 3 of of IN cord-022526-j9kg00qf 5030 4 the the DT cord-022526-j9kg00qf 5030 5 contents content NNS cord-022526-j9kg00qf 5030 6 likely likely RB cord-022526-j9kg00qf 5030 7 is be VBZ cord-022526-j9kg00qf 5030 8 related relate VBN cord-022526-j9kg00qf 5030 9 to to IN cord-022526-j9kg00qf 5030 10 the the DT cord-022526-j9kg00qf 5030 11 more more RBR cord-022526-j9kg00qf 5030 12 rapid rapid JJ cord-022526-j9kg00qf 5030 13 progression progression NN cord-022526-j9kg00qf 5030 14 of of IN cord-022526-j9kg00qf 5030 15 this this DT cord-022526-j9kg00qf 5030 16 disease disease NN cord-022526-j9kg00qf 5030 17 compared compare VBN cord-022526-j9kg00qf 5030 18 with with IN cord-022526-j9kg00qf 5030 19 primary primary JJ cord-022526-j9kg00qf 5030 20 cecal cecal JJ cord-022526-j9kg00qf 5030 21 impaction impaction NN cord-022526-j9kg00qf 5030 22 . . . cord-022526-j9kg00qf 5031 1 One one PRP cord-022526-j9kg00qf 5031 2 should should MD cord-022526-j9kg00qf 5031 3 not not RB cord-022526-j9kg00qf 5031 4 delay delay VB cord-022526-j9kg00qf 5031 5 surgery surgery NN cord-022526-j9kg00qf 5031 6 because because IN cord-022526-j9kg00qf 5031 7 of of IN cord-022526-j9kg00qf 5031 8 the the DT cord-022526-j9kg00qf 5031 9 risk risk NN cord-022526-j9kg00qf 5031 10 of of IN cord-022526-j9kg00qf 5031 11 cecal cecal JJ cord-022526-j9kg00qf 5031 12 rupture rupture NN cord-022526-j9kg00qf 5031 13 . . . cord-022526-j9kg00qf 5032 1 82 82 CD cord-022526-j9kg00qf 5033 1 However however RB cord-022526-j9kg00qf 5033 2 , , , cord-022526-j9kg00qf 5033 3 if if IN cord-022526-j9kg00qf 5033 4 the the DT cord-022526-j9kg00qf 5033 5 cecum cecum NN cord-022526-j9kg00qf 5033 6 appears appear VBZ cord-022526-j9kg00qf 5033 7 healthy healthy JJ cord-022526-j9kg00qf 5033 8 following follow VBG cord-022526-j9kg00qf 5033 9 typhlotomy typhlotomy NN cord-022526-j9kg00qf 5033 10 and and CC cord-022526-j9kg00qf 5033 11 evacuation evacuation NN cord-022526-j9kg00qf 5033 12 , , , cord-022526-j9kg00qf 5033 13 bypass bypass NN cord-022526-j9kg00qf 5033 14 of of IN cord-022526-j9kg00qf 5033 15 the the DT cord-022526-j9kg00qf 5033 16 cecum cecum NN cord-022526-j9kg00qf 5033 17 is be VBZ cord-022526-j9kg00qf 5033 18 not not RB cord-022526-j9kg00qf 5033 19 as as RB cord-022526-j9kg00qf 5033 20 critical critical JJ cord-022526-j9kg00qf 5033 21 as as IN cord-022526-j9kg00qf 5033 22 it -PRON- PRP cord-022526-j9kg00qf 5033 23 is be VBZ cord-022526-j9kg00qf 5033 24 for for IN cord-022526-j9kg00qf 5033 25 primary primary JJ cord-022526-j9kg00qf 5033 26 impactions impaction NNS cord-022526-j9kg00qf 5033 27 as as RB cord-022526-j9kg00qf 5033 28 long long RB cord-022526-j9kg00qf 5033 29 as as IN cord-022526-j9kg00qf 5033 30 one one PRP cord-022526-j9kg00qf 5033 31 can can MD cord-022526-j9kg00qf 5033 32 control control VB cord-022526-j9kg00qf 5033 33 the the DT cord-022526-j9kg00qf 5033 34 inciting incite VBG cord-022526-j9kg00qf 5033 35 cause cause NN cord-022526-j9kg00qf 5033 36 of of IN cord-022526-j9kg00qf 5033 37 the the DT cord-022526-j9kg00qf 5033 38 impaction impaction NN cord-022526-j9kg00qf 5033 39 ( ( -LRB- cord-022526-j9kg00qf 5033 40 such such JJ cord-022526-j9kg00qf 5033 41 as as IN cord-022526-j9kg00qf 5033 42 orthopedic orthopedic NN cord-022526-j9kg00qf 5033 43 pain pain NN cord-022526-j9kg00qf 5033 44 ) ) -RRB- cord-022526-j9kg00qf 5033 45 . . . cord-022526-j9kg00qf 5034 1 The the DT cord-022526-j9kg00qf 5034 2 prognosis prognosis NN cord-022526-j9kg00qf 5034 3 is be VBZ cord-022526-j9kg00qf 5034 4 guarded guard VBN cord-022526-j9kg00qf 5034 5 for for IN cord-022526-j9kg00qf 5034 6 surgical surgical JJ cord-022526-j9kg00qf 5034 7 treatment treatment NN cord-022526-j9kg00qf 5034 8 of of IN cord-022526-j9kg00qf 5034 9 all all DT cord-022526-j9kg00qf 5034 10 cecal cecal JJ cord-022526-j9kg00qf 5034 11 impactions impaction NNS cord-022526-j9kg00qf 5034 12 because because IN cord-022526-j9kg00qf 5034 13 of of IN cord-022526-j9kg00qf 5034 14 the the DT cord-022526-j9kg00qf 5034 15 potential potential NN cord-022526-j9kg00qf 5034 16 for for IN cord-022526-j9kg00qf 5034 17 the the DT cord-022526-j9kg00qf 5034 18 cecum cecum NN cord-022526-j9kg00qf 5034 19 to to TO cord-022526-j9kg00qf 5034 20 rupture rupture VB cord-022526-j9kg00qf 5034 21 during during IN cord-022526-j9kg00qf 5034 22 prolonged prolonged JJ cord-022526-j9kg00qf 5034 23 medical medical JJ cord-022526-j9kg00qf 5034 24 treatment treatment NN cord-022526-j9kg00qf 5034 25 or or CC cord-022526-j9kg00qf 5034 26 during during IN cord-022526-j9kg00qf 5034 27 surgical surgical JJ cord-022526-j9kg00qf 5034 28 manipulation manipulation NN cord-022526-j9kg00qf 5034 29 , , , cord-022526-j9kg00qf 5034 30 the the DT cord-022526-j9kg00qf 5034 31 possibility possibility NN cord-022526-j9kg00qf 5034 32 of of IN cord-022526-j9kg00qf 5034 33 abdominal abdominal JJ cord-022526-j9kg00qf 5034 34 contamination contamination NN cord-022526-j9kg00qf 5034 35 during during IN cord-022526-j9kg00qf 5034 36 surgery surgery NN cord-022526-j9kg00qf 5034 37 , , , cord-022526-j9kg00qf 5034 38 and and CC cord-022526-j9kg00qf 5034 39 the the DT cord-022526-j9kg00qf 5034 40 extensive extensive JJ cord-022526-j9kg00qf 5034 41 surgical surgical JJ cord-022526-j9kg00qf 5034 42 procedures procedure NNS cord-022526-j9kg00qf 5034 43 required require VBN cord-022526-j9kg00qf 5034 44 . . . cord-022526-j9kg00qf 5035 1 In in IN cord-022526-j9kg00qf 5035 2 a a DT cord-022526-j9kg00qf 5035 3 recent recent JJ cord-022526-j9kg00qf 5035 4 report report NN cord-022526-j9kg00qf 5035 5 , , , cord-022526-j9kg00qf 5035 6 seven seven CD cord-022526-j9kg00qf 5035 7 of of IN cord-022526-j9kg00qf 5035 8 nine nine CD cord-022526-j9kg00qf 5035 9 horses horse NNS cord-022526-j9kg00qf 5035 10 for for IN cord-022526-j9kg00qf 5035 11 which which WDT cord-022526-j9kg00qf 5035 12 cecal cecal JJ cord-022526-j9kg00qf 5035 13 impaction impaction NN cord-022526-j9kg00qf 5035 14 was be VBD cord-022526-j9kg00qf 5035 15 treated treat VBN cord-022526-j9kg00qf 5035 16 by by IN cord-022526-j9kg00qf 5035 17 typhlotomy typhlotomy NN cord-022526-j9kg00qf 5035 18 and and CC cord-022526-j9kg00qf 5035 19 ileocolostomy ileocolostomy NN cord-022526-j9kg00qf 5035 20 or or CC cord-022526-j9kg00qf 5035 21 jejunocolostomy jejunocolostomy NN cord-022526-j9kg00qf 5035 22 lived live VBD cord-022526-j9kg00qf 5035 23 long long JJ cord-022526-j9kg00qf 5035 24 term term NN cord-022526-j9kg00qf 5035 25 . . . cord-022526-j9kg00qf 5036 1 46 46 CD cord-022526-j9kg00qf 5037 1 However however RB cord-022526-j9kg00qf 5037 2 , , , cord-022526-j9kg00qf 5037 3 a a DT cord-022526-j9kg00qf 5037 4 separate separate JJ cord-022526-j9kg00qf 5037 5 report report NN cord-022526-j9kg00qf 5037 6 indicated indicate VBD cord-022526-j9kg00qf 5037 7 that that IN cord-022526-j9kg00qf 5037 8 all all DT cord-022526-j9kg00qf 5037 9 horses horse NNS cord-022526-j9kg00qf 5037 10 with with IN cord-022526-j9kg00qf 5037 11 cecal cecal JJ cord-022526-j9kg00qf 5037 12 impaction impaction NN cord-022526-j9kg00qf 5037 13 following follow VBG cord-022526-j9kg00qf 5037 14 another another DT cord-022526-j9kg00qf 5037 15 disease disease NN cord-022526-j9kg00qf 5037 16 process process NN cord-022526-j9kg00qf 5037 17 had have VBD cord-022526-j9kg00qf 5037 18 cecal cecal JJ cord-022526-j9kg00qf 5037 19 rupture rupture NN cord-022526-j9kg00qf 5037 20 without without IN cord-022526-j9kg00qf 5037 21 any any DT cord-022526-j9kg00qf 5037 22 signs sign NNS cord-022526-j9kg00qf 5037 23 of of IN cord-022526-j9kg00qf 5037 24 impending impend VBG cord-022526-j9kg00qf 5037 25 rupture rupture NN cord-022526-j9kg00qf 5037 26 . . . cord-022526-j9kg00qf 5038 1 80 80 CD cord-022526-j9kg00qf 5039 1 Ingesta Ingesta NNP cord-022526-j9kg00qf 5039 2 impactions impaction NNS cord-022526-j9kg00qf 5039 3 of of IN cord-022526-j9kg00qf 5039 4 the the DT cord-022526-j9kg00qf 5039 5 large large JJ cord-022526-j9kg00qf 5039 6 colon colon NN cord-022526-j9kg00qf 5039 7 occur occur VBP cord-022526-j9kg00qf 5039 8 at at IN cord-022526-j9kg00qf 5039 9 sites site NNS cord-022526-j9kg00qf 5039 10 of of IN cord-022526-j9kg00qf 5039 11 anatomic anatomic JJ cord-022526-j9kg00qf 5039 12 reductions reduction NNS cord-022526-j9kg00qf 5039 13 in in IN cord-022526-j9kg00qf 5039 14 luminal luminal JJ cord-022526-j9kg00qf 5039 15 diameter diameter NN cord-022526-j9kg00qf 5039 16 , , , cord-022526-j9kg00qf 5039 17 particularly particularly RB cord-022526-j9kg00qf 5039 18 the the DT cord-022526-j9kg00qf 5039 19 pelvic pelvic JJ cord-022526-j9kg00qf 5039 20 flexure flexure NN cord-022526-j9kg00qf 5039 21 and and CC cord-022526-j9kg00qf 5039 22 the the DT cord-022526-j9kg00qf 5039 23 right right JJ cord-022526-j9kg00qf 5039 24 dorsal dorsal JJ cord-022526-j9kg00qf 5039 25 colon colon NN cord-022526-j9kg00qf 5039 26 . . . cord-022526-j9kg00qf 5040 1 83 83 CD cord-022526-j9kg00qf 5041 1 Although although IN cord-022526-j9kg00qf 5041 2 a a DT cord-022526-j9kg00qf 5041 3 number number NN cord-022526-j9kg00qf 5041 4 of of IN cord-022526-j9kg00qf 5041 5 risk risk NN cord-022526-j9kg00qf 5041 6 factors factor NNS cord-022526-j9kg00qf 5041 7 have have VBP cord-022526-j9kg00qf 5041 8 been be VBN cord-022526-j9kg00qf 5041 9 reported report VBN cord-022526-j9kg00qf 5041 10 , , , cord-022526-j9kg00qf 5041 11 most most JJS cord-022526-j9kg00qf 5041 12 have have VBP cord-022526-j9kg00qf 5041 13 not not RB cord-022526-j9kg00qf 5041 14 been be VBN cord-022526-j9kg00qf 5041 15 proved prove VBN cord-022526-j9kg00qf 5041 16 . . . cord-022526-j9kg00qf 5042 1 However however RB cord-022526-j9kg00qf 5042 2 , , , cord-022526-j9kg00qf 5042 3 a a DT cord-022526-j9kg00qf 5042 4 sudden sudden JJ cord-022526-j9kg00qf 5042 5 restriction restriction NN cord-022526-j9kg00qf 5042 6 in in IN cord-022526-j9kg00qf 5042 7 exercise exercise NN cord-022526-j9kg00qf 5042 8 associated associate VBN cord-022526-j9kg00qf 5042 9 with with IN cord-022526-j9kg00qf 5042 10 musculoskeletal musculoskeletal JJ cord-022526-j9kg00qf 5042 11 injury injury NN cord-022526-j9kg00qf 5042 12 appears appear VBZ cord-022526-j9kg00qf 5042 13 frequently frequently RB cord-022526-j9kg00qf 5042 14 to to TO cord-022526-j9kg00qf 5042 15 be be VB cord-022526-j9kg00qf 5042 16 associated associate VBN cord-022526-j9kg00qf 5042 17 with with IN cord-022526-j9kg00qf 5042 18 onset onset NN cord-022526-j9kg00qf 5042 19 of of IN cord-022526-j9kg00qf 5042 20 impaction impaction NN cord-022526-j9kg00qf 5042 21 . . . cord-022526-j9kg00qf 5043 1 84 84 CD cord-022526-j9kg00qf 5044 1 Another another DT cord-022526-j9kg00qf 5044 2 consideration consideration NN cord-022526-j9kg00qf 5044 3 is be VBZ cord-022526-j9kg00qf 5044 4 equine equine JJ cord-022526-j9kg00qf 5044 5 feeding feed VBG cord-022526-j9kg00qf 5044 6 regimens regimen NNS cord-022526-j9kg00qf 5044 7 , , , cord-022526-j9kg00qf 5044 8 which which WDT cord-022526-j9kg00qf 5044 9 usually usually RB cord-022526-j9kg00qf 5044 10 entail entail VBP cord-022526-j9kg00qf 5044 11 twice twice JJ cord-022526-j9kg00qf 5044 12 daily daily JJ cord-022526-j9kg00qf 5044 13 feeding feeding NN cord-022526-j9kg00qf 5044 14 of of IN cord-022526-j9kg00qf 5044 15 concentrate concentrate NN cord-022526-j9kg00qf 5044 16 . . . cord-022526-j9kg00qf 5045 1 Such such JJ cord-022526-j9kg00qf 5045 2 regimens regimen NNS cord-022526-j9kg00qf 5045 3 are be VBP cord-022526-j9kg00qf 5045 4 associated associate VBN cord-022526-j9kg00qf 5045 5 with with IN cord-022526-j9kg00qf 5045 6 large large JJ cord-022526-j9kg00qf 5045 7 fluxes flux NNS cord-022526-j9kg00qf 5045 8 of of IN cord-022526-j9kg00qf 5045 9 fluid fluid NN cord-022526-j9kg00qf 5045 10 into into IN cord-022526-j9kg00qf 5045 11 and and CC cord-022526-j9kg00qf 5045 12 out out IN cord-022526-j9kg00qf 5045 13 of of IN cord-022526-j9kg00qf 5045 14 the the DT cord-022526-j9kg00qf 5045 15 colon colon NN cord-022526-j9kg00qf 5045 16 , , , cord-022526-j9kg00qf 5045 17 associated associate VBN cord-022526-j9kg00qf 5045 18 with with IN cord-022526-j9kg00qf 5045 19 readily readily RB cord-022526-j9kg00qf 5045 20 fermentable fermentable JJ cord-022526-j9kg00qf 5045 21 carbohydrate carbohydrate NN cord-022526-j9kg00qf 5045 22 in in IN cord-022526-j9kg00qf 5045 23 the the DT cord-022526-j9kg00qf 5045 24 colon colon NN cord-022526-j9kg00qf 5045 25 and and CC cord-022526-j9kg00qf 5045 26 subsequent subsequent JJ cord-022526-j9kg00qf 5045 27 increases increase NNS cord-022526-j9kg00qf 5045 28 in in IN cord-022526-j9kg00qf 5045 29 serum serum NN cord-022526-j9kg00qf 5045 30 aldosterone aldosterone NN cord-022526-j9kg00qf 5045 31 , , , cord-022526-j9kg00qf 5045 32 respectively respectively RB cord-022526-j9kg00qf 5045 33 . . . cord-022526-j9kg00qf 5046 1 One one CD cord-022526-j9kg00qf 5046 2 may may MD cord-022526-j9kg00qf 5046 3 prevent prevent VB cord-022526-j9kg00qf 5046 4 these these DT cord-022526-j9kg00qf 5046 5 fluid fluid JJ cord-022526-j9kg00qf 5046 6 fluxes flux NNS cord-022526-j9kg00qf 5046 7 , , , cord-022526-j9kg00qf 5046 8 which which WDT cord-022526-j9kg00qf 5046 9 may may MD cord-022526-j9kg00qf 5046 10 cause cause VB cord-022526-j9kg00qf 5046 11 dehydration dehydration NN cord-022526-j9kg00qf 5046 12 of of IN cord-022526-j9kg00qf 5046 13 ingesta ingesta NNS cord-022526-j9kg00qf 5046 14 during during IN cord-022526-j9kg00qf 5046 15 aldosterone aldosterone NN cord-022526-j9kg00qf 5046 16 - - HYPH cord-022526-j9kg00qf 5046 17 stimulated stimulate VBN cord-022526-j9kg00qf 5046 18 net net JJ cord-022526-j9kg00qf 5046 19 fluid fluid NN cord-022526-j9kg00qf 5046 20 flux flux NN cord-022526-j9kg00qf 5046 21 out out IN cord-022526-j9kg00qf 5046 22 of of IN cord-022526-j9kg00qf 5046 23 the the DT cord-022526-j9kg00qf 5046 24 colon colon NN cord-022526-j9kg00qf 5046 25 , , , cord-022526-j9kg00qf 5046 26 with with IN cord-022526-j9kg00qf 5046 27 frequent frequent JJ cord-022526-j9kg00qf 5046 28 small small JJ cord-022526-j9kg00qf 5046 29 feedings feeding NNS cord-022526-j9kg00qf 5046 30 . . . cord-022526-j9kg00qf 5047 1 32 32 CD cord-022526-j9kg00qf 5047 2 Amitraz Amitraz NNP cord-022526-j9kg00qf 5047 3 , , , cord-022526-j9kg00qf 5047 4 an an DT cord-022526-j9kg00qf 5047 5 acaricide acaricide NN cord-022526-j9kg00qf 5047 6 associated associate VBN cord-022526-j9kg00qf 5047 7 with with IN cord-022526-j9kg00qf 5047 8 clinical clinical JJ cord-022526-j9kg00qf 5047 9 cases case NNS cord-022526-j9kg00qf 5047 10 of of IN cord-022526-j9kg00qf 5047 11 colon colon NN cord-022526-j9kg00qf 5047 12 impaction impaction NN cord-022526-j9kg00qf 5047 13 , , , cord-022526-j9kg00qf 5047 14 can can MD cord-022526-j9kg00qf 5047 15 induce induce VB cord-022526-j9kg00qf 5047 16 impaction impaction NN cord-022526-j9kg00qf 5047 17 of of IN cord-022526-j9kg00qf 5047 18 the the DT cord-022526-j9kg00qf 5047 19 ascending ascend VBG cord-022526-j9kg00qf 5047 20 colon colon NN cord-022526-j9kg00qf 5047 21 . . . cord-022526-j9kg00qf 5048 1 85 85 CD cord-022526-j9kg00qf 5048 2 , , , cord-022526-j9kg00qf 5048 3 86 86 CD cord-022526-j9kg00qf 5049 1 This this DT cord-022526-j9kg00qf 5049 2 effect effect NN cord-022526-j9kg00qf 5049 3 may may MD cord-022526-j9kg00qf 5049 4 provide provide VB cord-022526-j9kg00qf 5049 5 some some DT cord-022526-j9kg00qf 5049 6 clues clue NNS cord-022526-j9kg00qf 5049 7 as as IN cord-022526-j9kg00qf 5049 8 to to IN cord-022526-j9kg00qf 5049 9 the the DT cord-022526-j9kg00qf 5049 10 pathogenesis pathogenesis NN cord-022526-j9kg00qf 5049 11 of of IN cord-022526-j9kg00qf 5049 12 large large JJ cord-022526-j9kg00qf 5049 13 colon colon NN cord-022526-j9kg00qf 5049 14 impaction impaction NN cord-022526-j9kg00qf 5049 15 . . . cord-022526-j9kg00qf 5050 1 In in IN cord-022526-j9kg00qf 5050 2 particular particular JJ cord-022526-j9kg00qf 5050 3 , , , cord-022526-j9kg00qf 5050 4 amitraz amitraz NNP cord-022526-j9kg00qf 5050 5 appears appear VBZ cord-022526-j9kg00qf 5050 6 to to TO cord-022526-j9kg00qf 5050 7 alter alter VB cord-022526-j9kg00qf 5050 8 pelvic pelvic JJ cord-022526-j9kg00qf 5050 9 flexure flexure NN cord-022526-j9kg00qf 5050 10 pacemaker pacemaker NN cord-022526-j9kg00qf 5050 11 activity activity NN cord-022526-j9kg00qf 5050 12 , , , cord-022526-j9kg00qf 5050 13 resulting result VBG cord-022526-j9kg00qf 5050 14 in in IN cord-022526-j9kg00qf 5050 15 uncoordinated uncoordinated JJ cord-022526-j9kg00qf 5050 16 motility motility NN cord-022526-j9kg00qf 5050 17 patterns pattern NNS cord-022526-j9kg00qf 5050 18 between between IN cord-022526-j9kg00qf 5050 19 the the DT cord-022526-j9kg00qf 5050 20 left left JJ cord-022526-j9kg00qf 5050 21 ventral ventral JJ cord-022526-j9kg00qf 5050 22 and and CC cord-022526-j9kg00qf 5050 23 left left JJ cord-022526-j9kg00qf 5050 24 dorsal dorsal JJ cord-022526-j9kg00qf 5050 25 colon colon NN cord-022526-j9kg00qf 5050 26 and and CC cord-022526-j9kg00qf 5050 27 excessive excessive JJ cord-022526-j9kg00qf 5050 28 retention retention NN cord-022526-j9kg00qf 5050 29 of of IN cord-022526-j9kg00qf 5050 30 ingesta ingesta NNP cord-022526-j9kg00qf 5050 31 . . . cord-022526-j9kg00qf 5051 1 Absorption absorption NN cord-022526-j9kg00qf 5051 2 of of IN cord-022526-j9kg00qf 5051 3 water water NN cord-022526-j9kg00qf 5051 4 from from IN cord-022526-j9kg00qf 5051 5 the the DT cord-022526-j9kg00qf 5051 6 ingesta ingesta NNP cord-022526-j9kg00qf 5051 7 increases increase VBZ cord-022526-j9kg00qf 5051 8 with with IN cord-022526-j9kg00qf 5051 9 retention retention NN cord-022526-j9kg00qf 5051 10 time time NN cord-022526-j9kg00qf 5051 11 , , , cord-022526-j9kg00qf 5051 12 dehydrates dehydrate VBZ cord-022526-j9kg00qf 5051 13 the the DT cord-022526-j9kg00qf 5051 14 contents content NNS cord-022526-j9kg00qf 5051 15 of of IN cord-022526-j9kg00qf 5051 16 the the DT cord-022526-j9kg00qf 5051 17 colon colon NN cord-022526-j9kg00qf 5051 18 , , , cord-022526-j9kg00qf 5051 19 and and CC cord-022526-j9kg00qf 5051 20 results result NNS cord-022526-j9kg00qf 5051 21 in in IN cord-022526-j9kg00qf 5051 22 impaction impaction NN cord-022526-j9kg00qf 5051 23 . . . cord-022526-j9kg00qf 5052 1 Conceivably conceivably RB cord-022526-j9kg00qf 5052 2 , , , cord-022526-j9kg00qf 5052 3 parasite parasite NN cord-022526-j9kg00qf 5052 4 migration migration NN cord-022526-j9kg00qf 5052 5 in in IN cord-022526-j9kg00qf 5052 6 the the DT cord-022526-j9kg00qf 5052 7 region region NN cord-022526-j9kg00qf 5052 8 of of IN cord-022526-j9kg00qf 5052 9 a a DT cord-022526-j9kg00qf 5052 10 pacemaker pacemaker NN cord-022526-j9kg00qf 5052 11 may may MD cord-022526-j9kg00qf 5052 12 have have VB cord-022526-j9kg00qf 5052 13 a a DT cord-022526-j9kg00qf 5052 14 similar similar JJ cord-022526-j9kg00qf 5052 15 action action NN cord-022526-j9kg00qf 5052 16 . . . cord-022526-j9kg00qf 5053 1 87 87 CD cord-022526-j9kg00qf 5054 1 Other other JJ cord-022526-j9kg00qf 5054 2 factors factor NNS cord-022526-j9kg00qf 5054 3 implicated implicate VBN cord-022526-j9kg00qf 5054 4 in in IN cord-022526-j9kg00qf 5054 5 large large JJ cord-022526-j9kg00qf 5054 6 colon colon NN cord-022526-j9kg00qf 5054 7 impaction impaction NN cord-022526-j9kg00qf 5054 8 include include VBP cord-022526-j9kg00qf 5054 9 limited limited JJ cord-022526-j9kg00qf 5054 10 exercise exercise NN cord-022526-j9kg00qf 5054 11 , , , cord-022526-j9kg00qf 5054 12 poor poor JJ cord-022526-j9kg00qf 5054 13 dentition dentition NN cord-022526-j9kg00qf 5054 14 , , , cord-022526-j9kg00qf 5054 15 coarse coarse JJ cord-022526-j9kg00qf 5054 16 roughage roughage NN cord-022526-j9kg00qf 5054 17 , , , cord-022526-j9kg00qf 5054 18 or or CC cord-022526-j9kg00qf 5054 19 dehydration dehydration NN cord-022526-j9kg00qf 5054 20 . . . cord-022526-j9kg00qf 5055 1 Clinical clinical JJ cord-022526-j9kg00qf 5055 2 signs sign NNS cord-022526-j9kg00qf 5055 3 of of IN cord-022526-j9kg00qf 5055 4 large large JJ cord-022526-j9kg00qf 5055 5 colon colon NN cord-022526-j9kg00qf 5055 6 impaction impaction NN cord-022526-j9kg00qf 5055 7 include include VBP cord-022526-j9kg00qf 5055 8 slow slow JJ cord-022526-j9kg00qf 5055 9 onset onset NN cord-022526-j9kg00qf 5055 10 of of IN cord-022526-j9kg00qf 5055 11 mild mild JJ cord-022526-j9kg00qf 5055 12 to to IN cord-022526-j9kg00qf 5055 13 moderate moderate JJ cord-022526-j9kg00qf 5055 14 colic colic NN cord-022526-j9kg00qf 5055 15 . . . cord-022526-j9kg00qf 5056 1 Fecal fecal JJ cord-022526-j9kg00qf 5056 2 production production NN cord-022526-j9kg00qf 5056 3 decreases decrease NNS cord-022526-j9kg00qf 5056 4 , , , cord-022526-j9kg00qf 5056 5 and and CC cord-022526-j9kg00qf 5056 6 the the DT cord-022526-j9kg00qf 5056 7 feces fece NNS cord-022526-j9kg00qf 5056 8 are be VBP cord-022526-j9kg00qf 5056 9 often often RB cord-022526-j9kg00qf 5056 10 hard hard JJ cord-022526-j9kg00qf 5056 11 , , , cord-022526-j9kg00qf 5056 12 dry dry JJ cord-022526-j9kg00qf 5056 13 , , , cord-022526-j9kg00qf 5056 14 and and CC cord-022526-j9kg00qf 5056 15 mucuscovered mucuscovere VBD cord-022526-j9kg00qf 5056 16 because because IN cord-022526-j9kg00qf 5056 17 of of IN cord-022526-j9kg00qf 5056 18 delayed delay VBN cord-022526-j9kg00qf 5056 19 transit transit NN cord-022526-j9kg00qf 5056 20 time time NN cord-022526-j9kg00qf 5056 21 . . . cord-022526-j9kg00qf 5057 1 The the DT cord-022526-j9kg00qf 5057 2 heart heart NN cord-022526-j9kg00qf 5057 3 rate rate NN cord-022526-j9kg00qf 5057 4 may may MD cord-022526-j9kg00qf 5057 5 be be VB cord-022526-j9kg00qf 5057 6 elevated elevate VBN cord-022526-j9kg00qf 5057 7 mildly mildly RB cord-022526-j9kg00qf 5057 8 during during IN cord-022526-j9kg00qf 5057 9 episodes episode NNS cord-022526-j9kg00qf 5057 10 of of IN cord-022526-j9kg00qf 5057 11 pain pain NN cord-022526-j9kg00qf 5057 12 but but CC cord-022526-j9kg00qf 5057 13 is be VBZ cord-022526-j9kg00qf 5057 14 often often RB cord-022526-j9kg00qf 5057 15 normal normal JJ cord-022526-j9kg00qf 5057 16 . . . cord-022526-j9kg00qf 5058 1 Signs sign NNS cord-022526-j9kg00qf 5058 2 of of IN cord-022526-j9kg00qf 5058 3 abdominal abdominal JJ cord-022526-j9kg00qf 5058 4 pain pain NN cord-022526-j9kg00qf 5058 5 are be VBP cord-022526-j9kg00qf 5058 6 typically typically RB cord-022526-j9kg00qf 5058 7 well well RB cord-022526-j9kg00qf 5058 8 controlled control VBN cord-022526-j9kg00qf 5058 9 with with IN cord-022526-j9kg00qf 5058 10 administration administration NN cord-022526-j9kg00qf 5058 11 of of IN cord-022526-j9kg00qf 5058 12 analgesics analgesic NNS cord-022526-j9kg00qf 5058 13 but but CC cord-022526-j9kg00qf 5058 14 become become VBP cord-022526-j9kg00qf 5058 15 increasingly increasingly RB cord-022526-j9kg00qf 5058 16 more more RBR cord-022526-j9kg00qf 5058 17 severe severe JJ cord-022526-j9kg00qf 5058 18 and and CC cord-022526-j9kg00qf 5058 19 refractory refractory JJ cord-022526-j9kg00qf 5058 20 if if IN cord-022526-j9kg00qf 5058 21 the the DT cord-022526-j9kg00qf 5058 22 impaction impaction NN cord-022526-j9kg00qf 5058 23 does do VBZ cord-022526-j9kg00qf 5058 24 not not RB cord-022526-j9kg00qf 5058 25 resolve resolve VB cord-022526-j9kg00qf 5058 26 . . . cord-022526-j9kg00qf 5059 1 The the DT cord-022526-j9kg00qf 5059 2 diagnosis diagnosis NN cord-022526-j9kg00qf 5059 3 is be VBZ cord-022526-j9kg00qf 5059 4 based base VBN cord-022526-j9kg00qf 5059 5 on on IN cord-022526-j9kg00qf 5059 6 palpation palpation NN cord-022526-j9kg00qf 5059 7 of of IN cord-022526-j9kg00qf 5059 8 a a DT cord-022526-j9kg00qf 5059 9 firm firm JJ cord-022526-j9kg00qf 5059 10 mass mass NN cord-022526-j9kg00qf 5059 11 in in IN cord-022526-j9kg00qf 5059 12 the the DT cord-022526-j9kg00qf 5059 13 large large JJ cord-022526-j9kg00qf 5059 14 colon colon NN cord-022526-j9kg00qf 5059 15 per per IN cord-022526-j9kg00qf 5059 16 rectum rectum NN cord-022526-j9kg00qf 5059 17 . . . cord-022526-j9kg00qf 5060 1 However however RB cord-022526-j9kg00qf 5060 2 , , , cord-022526-j9kg00qf 5060 3 one one PRP cord-022526-j9kg00qf 5060 4 may may MD cord-022526-j9kg00qf 5060 5 underestimate underestimate VB cord-022526-j9kg00qf 5060 6 the the DT cord-022526-j9kg00qf 5060 7 extent extent NN cord-022526-j9kg00qf 5060 8 of of IN cord-022526-j9kg00qf 5060 9 the the DT cord-022526-j9kg00qf 5060 10 impaction impaction NN cord-022526-j9kg00qf 5060 11 by by IN cord-022526-j9kg00qf 5060 12 rectal rectal JJ cord-022526-j9kg00qf 5060 13 palpation palpation NN cord-022526-j9kg00qf 5060 14 alone alone RB cord-022526-j9kg00qf 5060 15 because because IN cord-022526-j9kg00qf 5060 16 much much JJ cord-022526-j9kg00qf 5060 17 of of IN cord-022526-j9kg00qf 5060 18 the the DT cord-022526-j9kg00qf 5060 19 colon colon NN cord-022526-j9kg00qf 5060 20 is be VBZ cord-022526-j9kg00qf 5060 21 out out IN cord-022526-j9kg00qf 5060 22 of of IN cord-022526-j9kg00qf 5060 23 reach reach NN cord-022526-j9kg00qf 5060 24 . . . cord-022526-j9kg00qf 5061 1 Adjacent adjacent JJ cord-022526-j9kg00qf 5061 2 colon colon NN cord-022526-j9kg00qf 5061 3 may may MD cord-022526-j9kg00qf 5061 4 be be VB cord-022526-j9kg00qf 5061 5 distended distend VBN cord-022526-j9kg00qf 5061 6 if if IN cord-022526-j9kg00qf 5061 7 the the DT cord-022526-j9kg00qf 5061 8 impaction impaction NN cord-022526-j9kg00qf 5061 9 has have VBZ cord-022526-j9kg00qf 5061 10 resulted result VBN cord-022526-j9kg00qf 5061 11 in in IN cord-022526-j9kg00qf 5061 12 complete complete JJ cord-022526-j9kg00qf 5061 13 obstruction obstruction NN cord-022526-j9kg00qf 5061 14 . . . cord-022526-j9kg00qf 5062 1 One one PRP cord-022526-j9kg00qf 5062 2 should should MD cord-022526-j9kg00qf 5062 3 attempt attempt VB cord-022526-j9kg00qf 5062 4 initial initial JJ cord-022526-j9kg00qf 5062 5 medical medical JJ cord-022526-j9kg00qf 5062 6 treatment treatment NN cord-022526-j9kg00qf 5062 7 . . . cord-022526-j9kg00qf 5063 1 Administration administration NN cord-022526-j9kg00qf 5063 2 of of IN cord-022526-j9kg00qf 5063 3 analgesics analgesic NNS cord-022526-j9kg00qf 5063 4 ( ( -LRB- cord-022526-j9kg00qf 5063 5 e.g. e.g. RB cord-022526-j9kg00qf 5063 6 , , , cord-022526-j9kg00qf 5063 7 flunixin flunixin NNP cord-022526-j9kg00qf 5063 8 meglumine meglumine NNP cord-022526-j9kg00qf 5063 9 at at IN cord-022526-j9kg00qf 5063 10 0.5 0.5 CD cord-022526-j9kg00qf 5063 11 to to TO cord-022526-j9kg00qf 5063 12 1.1 1.1 CD cord-022526-j9kg00qf 5063 13 mg mg NN cord-022526-j9kg00qf 5064 1 /kg /kg NFP cord-022526-j9kg00qf 5064 2 intravenously intravenously RB cord-022526-j9kg00qf 5064 3 every every DT cord-022526-j9kg00qf 5064 4 8 8 CD cord-022526-j9kg00qf 5064 5 to to TO cord-022526-j9kg00qf 5064 6 12 12 CD cord-022526-j9kg00qf 5064 7 hours hour NNS cord-022526-j9kg00qf 5064 8 ; ; : cord-022526-j9kg00qf 5064 9 butorphanol butorphanol NN cord-022526-j9kg00qf 5064 10 at at IN cord-022526-j9kg00qf 5064 11 0.04 0.04 CD cord-022526-j9kg00qf 5064 12 to to IN cord-022526-j9kg00qf 5064 13 0.1 0.1 CD cord-022526-j9kg00qf 5064 14 mg mg NNP cord-022526-j9kg00qf 5064 15 / / SYM cord-022526-j9kg00qf 5064 16 kg kg NNS cord-022526-j9kg00qf 5064 17 intramuscularly intramuscularly RB cord-022526-j9kg00qf 5064 18 every every DT cord-022526-j9kg00qf 5064 19 4 4 CD cord-022526-j9kg00qf 5064 20 to to TO cord-022526-j9kg00qf 5064 21 6 6 CD cord-022526-j9kg00qf 5064 22 hours hour NNS cord-022526-j9kg00qf 5064 23 ; ; : cord-022526-j9kg00qf 5064 24 or or CC cord-022526-j9kg00qf 5064 25 xylazine xylazine NN cord-022526-j9kg00qf 5064 26 at at IN cord-022526-j9kg00qf 5064 27 0.3 0.3 CD cord-022526-j9kg00qf 5064 28 to to IN cord-022526-j9kg00qf 5064 29 0.5 0.5 CD cord-022526-j9kg00qf 5064 30 mg mg NNP cord-022526-j9kg00qf 5064 31 / / SYM cord-022526-j9kg00qf 5064 32 kg kg XX cord-022526-j9kg00qf 5064 33 intravenously intravenously RB cord-022526-j9kg00qf 5064 34 as as IN cord-022526-j9kg00qf 5064 35 needed need VBN cord-022526-j9kg00qf 5064 36 ) ) -RRB- cord-022526-j9kg00qf 5064 37 controls control VBZ cord-022526-j9kg00qf 5064 38 intermittent intermittent JJ cord-022526-j9kg00qf 5064 39 abdominal abdominal JJ cord-022526-j9kg00qf 5064 40 pain pain NN cord-022526-j9kg00qf 5064 41 . . . cord-022526-j9kg00qf 5065 1 Administration administration NN cord-022526-j9kg00qf 5065 2 of of IN cord-022526-j9kg00qf 5065 3 oral oral JJ cord-022526-j9kg00qf 5065 4 laxatives laxative NNS cord-022526-j9kg00qf 5065 5 such such JJ cord-022526-j9kg00qf 5065 6 as as IN cord-022526-j9kg00qf 5065 7 mineral mineral NN cord-022526-j9kg00qf 5065 8 oil oil NN cord-022526-j9kg00qf 5065 9 ( ( -LRB- cord-022526-j9kg00qf 5065 10 2 2 CD cord-022526-j9kg00qf 5065 11 to to IN cord-022526-j9kg00qf 5065 12 4 4 CD cord-022526-j9kg00qf 5065 13 L l NN cord-022526-j9kg00qf 5065 14 by by IN cord-022526-j9kg00qf 5065 15 nasogastric nasogastric NN cord-022526-j9kg00qf 5065 16 tube tube NN cord-022526-j9kg00qf 5065 17 every every DT cord-022526-j9kg00qf 5065 18 12 12 CD cord-022526-j9kg00qf 5065 19 to to TO cord-022526-j9kg00qf 5065 20 24 24 CD cord-022526-j9kg00qf 5065 21 hours hour NNS cord-022526-j9kg00qf 5065 22 ) ) -RRB- cord-022526-j9kg00qf 5065 23 and and CC cord-022526-j9kg00qf 5065 24 the the DT cord-022526-j9kg00qf 5065 25 anionic anionic JJ cord-022526-j9kg00qf 5065 26 surfactant surfactant NN cord-022526-j9kg00qf 5065 27 dioctyl dioctyl NNP cord-022526-j9kg00qf 5065 28 sodium sodium NNP cord-022526-j9kg00qf 5065 29 sulfosuccinate sulfosuccinate NNP cord-022526-j9kg00qf 5065 30 ( ( -LRB- cord-022526-j9kg00qf 5065 31 6 6 CD cord-022526-j9kg00qf 5065 32 to to TO cord-022526-j9kg00qf 5065 33 12 12 CD cord-022526-j9kg00qf 5065 34 g/500 g/500 NNP cord-022526-j9kg00qf 5065 35 kg kg NNS cord-022526-j9kg00qf 5065 36 diluted dilute VBN cord-022526-j9kg00qf 5065 37 in in IN cord-022526-j9kg00qf 5065 38 2 2 CD cord-022526-j9kg00qf 5065 39 to to IN cord-022526-j9kg00qf 5065 40 4 4 CD cord-022526-j9kg00qf 5065 41 L l NN cord-022526-j9kg00qf 5065 42 of of IN cord-022526-j9kg00qf 5065 43 water water NN cord-022526-j9kg00qf 5065 44 by by IN cord-022526-j9kg00qf 5065 45 nasogastric nasogastric NN cord-022526-j9kg00qf 5065 46 tube tube NN cord-022526-j9kg00qf 5065 47 every every DT cord-022526-j9kg00qf 5065 48 12 12 CD cord-022526-j9kg00qf 5065 49 to to TO cord-022526-j9kg00qf 5065 50 24 24 CD cord-022526-j9kg00qf 5065 51 hours hour NNS cord-022526-j9kg00qf 5065 52 ) ) -RRB- cord-022526-j9kg00qf 5065 53 are be VBP cord-022526-j9kg00qf 5065 54 used use VBN cord-022526-j9kg00qf 5065 55 commonly commonly RB cord-022526-j9kg00qf 5065 56 to to TO cord-022526-j9kg00qf 5065 57 soften soften VB cord-022526-j9kg00qf 5065 58 the the DT cord-022526-j9kg00qf 5065 59 impaction impaction NN cord-022526-j9kg00qf 5065 60 . . . cord-022526-j9kg00qf 5066 1 Saline Saline NNP cord-022526-j9kg00qf 5066 2 cathartics cathartic NNS cord-022526-j9kg00qf 5066 3 such such JJ cord-022526-j9kg00qf 5066 4 as as IN cord-022526-j9kg00qf 5066 5 magnesium magnesium NN cord-022526-j9kg00qf 5066 6 sulfate sulfate NN cord-022526-j9kg00qf 5066 7 ( ( -LRB- cord-022526-j9kg00qf 5066 8 0.1 0.1 CD cord-022526-j9kg00qf 5066 9 mg mg NNP cord-022526-j9kg00qf 5066 10 / / SYM cord-022526-j9kg00qf 5066 11 kg kg NNS cord-022526-j9kg00qf 5066 12 in in IN cord-022526-j9kg00qf 5066 13 2 2 CD cord-022526-j9kg00qf 5066 14 to to IN cord-022526-j9kg00qf 5066 15 4 4 CD cord-022526-j9kg00qf 5066 16 L l NN cord-022526-j9kg00qf 5066 17 by by IN cord-022526-j9kg00qf 5066 18 nasogastric nasogastric NN cord-022526-j9kg00qf 5066 19 tube tube NN cord-022526-j9kg00qf 5066 20 ) ) -RRB- cord-022526-j9kg00qf 5066 21 also also RB cord-022526-j9kg00qf 5066 22 may may MD cord-022526-j9kg00qf 5066 23 be be VB cord-022526-j9kg00qf 5066 24 useful useful JJ cord-022526-j9kg00qf 5066 25 . . . cord-022526-j9kg00qf 5067 1 One one PRP cord-022526-j9kg00qf 5067 2 should should MD cord-022526-j9kg00qf 5067 3 not not RB cord-022526-j9kg00qf 5067 4 permit permit VB cord-022526-j9kg00qf 5067 5 access access NN cord-022526-j9kg00qf 5067 6 to to IN cord-022526-j9kg00qf 5067 7 feed feed NN cord-022526-j9kg00qf 5067 8 . . . cord-022526-j9kg00qf 5068 1 For for IN cord-022526-j9kg00qf 5068 2 impactions impaction NNS cord-022526-j9kg00qf 5068 3 that that WDT cord-022526-j9kg00qf 5068 4 persist persist VBP cord-022526-j9kg00qf 5068 5 , , , cord-022526-j9kg00qf 5068 6 one one PRP cord-022526-j9kg00qf 5068 7 should should MD cord-022526-j9kg00qf 5068 8 institute institute VB cord-022526-j9kg00qf 5068 9 aggressive aggressive JJ cord-022526-j9kg00qf 5068 10 oral oral JJ cord-022526-j9kg00qf 5068 11 and and CC cord-022526-j9kg00qf 5068 12 intravenous intravenous JJ cord-022526-j9kg00qf 5068 13 fluid fluid NN cord-022526-j9kg00qf 5068 14 therapy therapy NN cord-022526-j9kg00qf 5068 15 ( ( -LRB- cord-022526-j9kg00qf 5068 16 2 2 CD cord-022526-j9kg00qf 5068 17 to to IN cord-022526-j9kg00qf 5068 18 4 4 CD cord-022526-j9kg00qf 5068 19 times time NNS cord-022526-j9kg00qf 5068 20 the the DT cord-022526-j9kg00qf 5068 21 maintenance maintenance NN cord-022526-j9kg00qf 5068 22 fluid fluid NN cord-022526-j9kg00qf 5068 23 requirement requirement NN cord-022526-j9kg00qf 5068 24 ) ) -RRB- cord-022526-j9kg00qf 5068 25 . . . cord-022526-j9kg00qf 5069 1 If if IN cord-022526-j9kg00qf 5069 2 the the DT cord-022526-j9kg00qf 5069 3 impaction impaction NN cord-022526-j9kg00qf 5069 4 remains remain VBZ cord-022526-j9kg00qf 5069 5 unresolved unresolved JJ cord-022526-j9kg00qf 5069 6 , , , cord-022526-j9kg00qf 5069 7 the the DT cord-022526-j9kg00qf 5069 8 horse horse NN cord-022526-j9kg00qf 5069 9 becomes become VBZ cord-022526-j9kg00qf 5069 10 uncontrollably uncontrollably RB cord-022526-j9kg00qf 5069 11 painful painful JJ cord-022526-j9kg00qf 5069 12 , , , cord-022526-j9kg00qf 5069 13 or or CC cord-022526-j9kg00qf 5069 14 extensive extensive JJ cord-022526-j9kg00qf 5069 15 gas gas NN cord-022526-j9kg00qf 5069 16 distention distention NN cord-022526-j9kg00qf 5069 17 of of IN cord-022526-j9kg00qf 5069 18 the the DT cord-022526-j9kg00qf 5069 19 colon colon NN cord-022526-j9kg00qf 5069 20 occurs occur VBZ cord-022526-j9kg00qf 5069 21 , , , cord-022526-j9kg00qf 5069 22 surgery surgery NN cord-022526-j9kg00qf 5069 23 is be VBZ cord-022526-j9kg00qf 5069 24 indicated indicate VBN cord-022526-j9kg00qf 5069 25 . . . cord-022526-j9kg00qf 5070 1 In in IN cord-022526-j9kg00qf 5070 2 addition addition NN cord-022526-j9kg00qf 5070 3 , , , cord-022526-j9kg00qf 5070 4 one one PRP cord-022526-j9kg00qf 5070 5 can can MD cord-022526-j9kg00qf 5070 6 monitor monitor VB cord-022526-j9kg00qf 5070 7 abdominal abdominal JJ cord-022526-j9kg00qf 5070 8 fluid fluid NN cord-022526-j9kg00qf 5070 9 serially serially RB cord-022526-j9kg00qf 5070 10 to to TO cord-022526-j9kg00qf 5070 11 determine determine VB cord-022526-j9kg00qf 5070 12 the the DT cord-022526-j9kg00qf 5070 13 onset onset NN cord-022526-j9kg00qf 5070 14 of of IN cord-022526-j9kg00qf 5070 15 intestinal intestinal JJ cord-022526-j9kg00qf 5070 16 compromise compromise NN cord-022526-j9kg00qf 5070 17 . . . cord-022526-j9kg00qf 5071 1 83 83 CD cord-022526-j9kg00qf 5072 1 At at IN cord-022526-j9kg00qf 5072 2 surgery surgery NN cord-022526-j9kg00qf 5072 3 , , , cord-022526-j9kg00qf 5072 4 one one PRP cord-022526-j9kg00qf 5072 5 evacuates evacuate VBZ cord-022526-j9kg00qf 5072 6 the the DT cord-022526-j9kg00qf 5072 7 contents content NNS cord-022526-j9kg00qf 5072 8 of of IN cord-022526-j9kg00qf 5072 9 the the DT cord-022526-j9kg00qf 5072 10 colon colon NN cord-022526-j9kg00qf 5072 11 via via IN cord-022526-j9kg00qf 5072 12 a a DT cord-022526-j9kg00qf 5072 13 pelvic pelvic JJ cord-022526-j9kg00qf 5072 14 flexure flexure NN cord-022526-j9kg00qf 5072 15 enterotomy enterotomy NN cord-022526-j9kg00qf 5072 16 . . . cord-022526-j9kg00qf 5073 1 The the DT cord-022526-j9kg00qf 5073 2 prognosis prognosis NN cord-022526-j9kg00qf 5073 3 is be VBZ cord-022526-j9kg00qf 5073 4 good good JJ cord-022526-j9kg00qf 5073 5 for for IN cord-022526-j9kg00qf 5073 6 those those DT cord-022526-j9kg00qf 5073 7 horses horse NNS cord-022526-j9kg00qf 5073 8 in in IN cord-022526-j9kg00qf 5073 9 which which WDT cord-022526-j9kg00qf 5073 10 impactions impaction NNS cord-022526-j9kg00qf 5073 11 resolve resolve VBP cord-022526-j9kg00qf 5073 12 medically medically RB cord-022526-j9kg00qf 5073 13 ( ( -LRB- cord-022526-j9kg00qf 5073 14 95 95 CD cord-022526-j9kg00qf 5073 15 % % NN cord-022526-j9kg00qf 5073 16 long long JJ cord-022526-j9kg00qf 5073 17 - - HYPH cord-022526-j9kg00qf 5073 18 term term NN cord-022526-j9kg00qf 5073 19 survival survival NN cord-022526-j9kg00qf 5073 20 in in IN cord-022526-j9kg00qf 5073 21 one one CD cord-022526-j9kg00qf 5073 22 study study NN cord-022526-j9kg00qf 5073 23 ) ) -RRB- cord-022526-j9kg00qf 5073 24 and and CC cord-022526-j9kg00qf 5073 25 fair fair JJ cord-022526-j9kg00qf 5073 26 in in IN cord-022526-j9kg00qf 5073 27 horses horse NNS cord-022526-j9kg00qf 5073 28 that that WDT cord-022526-j9kg00qf 5073 29 require require VBP cord-022526-j9kg00qf 5073 30 surgical surgical JJ cord-022526-j9kg00qf 5073 31 intervention intervention NN cord-022526-j9kg00qf 5073 32 ( ( -LRB- cord-022526-j9kg00qf 5073 33 58 58 CD cord-022526-j9kg00qf 5073 34 % % NN cord-022526-j9kg00qf 5073 35 long long JJ cord-022526-j9kg00qf 5073 36 - - HYPH cord-022526-j9kg00qf 5073 37 term term NN cord-022526-j9kg00qf 5073 38 survival survival NN cord-022526-j9kg00qf 5073 39 in in IN cord-022526-j9kg00qf 5073 40 the the DT cord-022526-j9kg00qf 5073 41 same same JJ cord-022526-j9kg00qf 5073 42 study study NN cord-022526-j9kg00qf 5073 43 ) ) -RRB- cord-022526-j9kg00qf 5073 44 . . . cord-022526-j9kg00qf 5074 1 84 84 CD cord-022526-j9kg00qf 5075 1 Enteroliths enterolith NNS cord-022526-j9kg00qf 5075 2 are be VBP cord-022526-j9kg00qf 5075 3 mineralized mineralized JJ cord-022526-j9kg00qf 5075 4 masses masse NNS cord-022526-j9kg00qf 5075 5 typically typically RB cord-022526-j9kg00qf 5075 6 composed compose VBN cord-022526-j9kg00qf 5075 7 of of IN cord-022526-j9kg00qf 5075 8 magnesium magnesium NN cord-022526-j9kg00qf 5075 9 ammonium ammonium NN cord-022526-j9kg00qf 5075 10 phosphate phosphate NN cord-022526-j9kg00qf 5075 11 ( ( -LRB- cord-022526-j9kg00qf 5075 12 struvite struvite NN cord-022526-j9kg00qf 5075 13 ) ) -RRB- cord-022526-j9kg00qf 5075 14 . . . cord-022526-j9kg00qf 5076 1 88 88 CD cord-022526-j9kg00qf 5077 1 However however RB cord-022526-j9kg00qf 5077 2 , , , cord-022526-j9kg00qf 5077 3 magnesium magnesium NN cord-022526-j9kg00qf 5077 4 vivianite vivianite NN cord-022526-j9kg00qf 5077 5 also also RB cord-022526-j9kg00qf 5077 6 has have VBZ cord-022526-j9kg00qf 5077 7 been be VBN cord-022526-j9kg00qf 5077 8 identified identify VBN cord-022526-j9kg00qf 5077 9 in in IN cord-022526-j9kg00qf 5077 10 enteroliths enterolith NNS cord-022526-j9kg00qf 5077 11 , , , cord-022526-j9kg00qf 5077 12 along along IN cord-022526-j9kg00qf 5077 13 with with IN cord-022526-j9kg00qf 5077 14 variable variable JJ cord-022526-j9kg00qf 5077 15 quantities quantity NNS cord-022526-j9kg00qf 5077 16 of of IN cord-022526-j9kg00qf 5077 17 sodium sodium NN cord-022526-j9kg00qf 5077 18 , , , cord-022526-j9kg00qf 5077 19 sulfur sulfur NN cord-022526-j9kg00qf 5077 20 , , , cord-022526-j9kg00qf 5077 21 potassium potassium NN cord-022526-j9kg00qf 5077 22 , , , cord-022526-j9kg00qf 5077 23 and and CC cord-022526-j9kg00qf 5077 24 calcium calcium NN cord-022526-j9kg00qf 5077 25 . . . cord-022526-j9kg00qf 5078 1 The the DT cord-022526-j9kg00qf 5078 2 formation formation NN cord-022526-j9kg00qf 5078 3 of of IN cord-022526-j9kg00qf 5078 4 magnesiumbased magnesiumbased JJ cord-022526-j9kg00qf 5078 5 minerals mineral NNS cord-022526-j9kg00qf 5078 6 is be VBZ cord-022526-j9kg00qf 5078 7 puzzling puzzle VBG cord-022526-j9kg00qf 5078 8 because because IN cord-022526-j9kg00qf 5078 9 of of IN cord-022526-j9kg00qf 5078 10 the the DT cord-022526-j9kg00qf 5078 11 relative relative JJ cord-022526-j9kg00qf 5078 12 abundance abundance NN cord-022526-j9kg00qf 5078 13 of of IN cord-022526-j9kg00qf 5078 14 calcium calcium NN cord-022526-j9kg00qf 5078 15 in in IN cord-022526-j9kg00qf 5078 16 colonic colonic JJ cord-022526-j9kg00qf 5078 17 fluids fluid NNS cord-022526-j9kg00qf 5078 18 , , , cord-022526-j9kg00qf 5078 19 which which WDT cord-022526-j9kg00qf 5078 20 would would MD cord-022526-j9kg00qf 5078 21 favor favor VB cord-022526-j9kg00qf 5078 22 the the DT cord-022526-j9kg00qf 5078 23 formation formation NN cord-022526-j9kg00qf 5078 24 of of IN cord-022526-j9kg00qf 5078 25 calcium calcium NN cord-022526-j9kg00qf 5078 26 phosphates phosphate NNS cord-022526-j9kg00qf 5078 27 ( ( -LRB- cord-022526-j9kg00qf 5078 28 apatite apatite NN cord-022526-j9kg00qf 5078 29 ) ) -RRB- cord-022526-j9kg00qf 5078 30 rather rather RB cord-022526-j9kg00qf 5078 31 than than IN cord-022526-j9kg00qf 5078 32 struvite struvite NN cord-022526-j9kg00qf 5078 33 . . . cord-022526-j9kg00qf 5079 1 89 89 CD cord-022526-j9kg00qf 5080 1 However however RB cord-022526-j9kg00qf 5080 2 , , , cord-022526-j9kg00qf 5080 3 elevated elevated JJ cord-022526-j9kg00qf 5080 4 dietary dietary JJ cord-022526-j9kg00qf 5080 5 intake intake NN cord-022526-j9kg00qf 5080 6 of of IN cord-022526-j9kg00qf 5080 7 magnesium magnesium NN cord-022526-j9kg00qf 5080 8 and and CC cord-022526-j9kg00qf 5080 9 protein protein NN cord-022526-j9kg00qf 5080 10 may may MD cord-022526-j9kg00qf 5080 11 play play VB cord-022526-j9kg00qf 5080 12 a a DT cord-022526-j9kg00qf 5080 13 role role NN cord-022526-j9kg00qf 5080 14 . . . cord-022526-j9kg00qf 5081 1 Many many JJ cord-022526-j9kg00qf 5081 2 horses horse NNS cord-022526-j9kg00qf 5081 3 that that WDT cord-022526-j9kg00qf 5081 4 develop develop VBP cord-022526-j9kg00qf 5081 5 enteroliths enterolith NNS cord-022526-j9kg00qf 5081 6 are be VBP cord-022526-j9kg00qf 5081 7 located locate VBN cord-022526-j9kg00qf 5081 8 in in IN cord-022526-j9kg00qf 5081 9 California California NNP cord-022526-j9kg00qf 5081 10 and and CC cord-022526-j9kg00qf 5081 11 are be VBP cord-022526-j9kg00qf 5081 12 fed feed VBN cord-022526-j9kg00qf 5081 13 a a DT cord-022526-j9kg00qf 5081 14 diet diet NN cord-022526-j9kg00qf 5081 15 consisting consist VBG cord-022526-j9kg00qf 5081 16 mainly mainly RB cord-022526-j9kg00qf 5081 17 of of IN cord-022526-j9kg00qf 5081 18 alfalfa alfalfa NN cord-022526-j9kg00qf 5081 19 hay hay NN cord-022526-j9kg00qf 5081 20 . . . cord-022526-j9kg00qf 5082 1 Analysis analysis NN cord-022526-j9kg00qf 5082 2 of of IN cord-022526-j9kg00qf 5082 3 this this DT cord-022526-j9kg00qf 5082 4 hay hay NN cord-022526-j9kg00qf 5082 5 has have VBZ cord-022526-j9kg00qf 5082 6 revealed reveal VBN cord-022526-j9kg00qf 5082 7 a a DT cord-022526-j9kg00qf 5082 8 concentration concentration NN cord-022526-j9kg00qf 5082 9 of of IN cord-022526-j9kg00qf 5082 10 magnesium magnesium NN cord-022526-j9kg00qf 5082 11 approximately approximately RB cord-022526-j9kg00qf 5082 12 6 6 CD cord-022526-j9kg00qf 5082 13 times time NNS cord-022526-j9kg00qf 5082 14 the the DT cord-022526-j9kg00qf 5082 15 daily daily JJ cord-022526-j9kg00qf 5082 16 requirements requirement NNS cord-022526-j9kg00qf 5082 17 of of IN cord-022526-j9kg00qf 5082 18 the the DT cord-022526-j9kg00qf 5082 19 horse horse NN cord-022526-j9kg00qf 5082 20 . . . cord-022526-j9kg00qf 5083 1 90 90 CD cord-022526-j9kg00qf 5084 1 Furthermore furthermore RB cord-022526-j9kg00qf 5084 2 , , , cord-022526-j9kg00qf 5084 3 the the DT cord-022526-j9kg00qf 5084 4 high high JJ cord-022526-j9kg00qf 5084 5 protein protein NN cord-022526-j9kg00qf 5084 6 concentration concentration NN cord-022526-j9kg00qf 5084 7 in in IN cord-022526-j9kg00qf 5084 8 alfalfa alfalfa NN cord-022526-j9kg00qf 5084 9 hay hay NN cord-022526-j9kg00qf 5084 10 may may MD cord-022526-j9kg00qf 5084 11 contribute contribute VB cord-022526-j9kg00qf 5084 12 to to IN cord-022526-j9kg00qf 5084 13 calculi calculus NNS cord-022526-j9kg00qf 5084 14 formation formation NN cord-022526-j9kg00qf 5084 15 by by IN cord-022526-j9kg00qf 5084 16 increasing increase VBG cord-022526-j9kg00qf 5084 17 the the DT cord-022526-j9kg00qf 5084 18 ammonia ammonia NN cord-022526-j9kg00qf 5084 19 nitrogen nitrogen NN cord-022526-j9kg00qf 5084 20 load load NN cord-022526-j9kg00qf 5084 21 in in IN cord-022526-j9kg00qf 5084 22 the the DT cord-022526-j9kg00qf 5084 23 large large JJ cord-022526-j9kg00qf 5084 24 intestine intestine NN cord-022526-j9kg00qf 5084 25 . . . cord-022526-j9kg00qf 5085 1 Enteroliths enterolith NNS cord-022526-j9kg00qf 5085 2 most most RBS cord-022526-j9kg00qf 5085 3 commonly commonly RB cord-022526-j9kg00qf 5085 4 form form VBP cord-022526-j9kg00qf 5085 5 around around IN cord-022526-j9kg00qf 5085 6 a a DT cord-022526-j9kg00qf 5085 7 nucleus nucleus NN cord-022526-j9kg00qf 5085 8 of of IN cord-022526-j9kg00qf 5085 9 silicon silicon NN cord-022526-j9kg00qf 5085 10 dioxide dioxide NN cord-022526-j9kg00qf 5085 11 ( ( -LRB- cord-022526-j9kg00qf 5085 12 a a DT cord-022526-j9kg00qf 5085 13 flintlike flintlike NNP cord-022526-j9kg00qf 5085 14 stone stone NN cord-022526-j9kg00qf 5085 15 ) ) -RRB- cord-022526-j9kg00qf 5085 16 , , , cord-022526-j9kg00qf 5085 17 but but CC cord-022526-j9kg00qf 5085 18 nidi nidi NNP cord-022526-j9kg00qf 5085 19 have have VBP cord-022526-j9kg00qf 5085 20 included include VBN cord-022526-j9kg00qf 5085 21 ingested ingest VBN cord-022526-j9kg00qf 5085 22 nails nail NNS cord-022526-j9kg00qf 5085 23 , , , cord-022526-j9kg00qf 5085 24 rope rope NN cord-022526-j9kg00qf 5085 25 , , , cord-022526-j9kg00qf 5085 26 and and CC cord-022526-j9kg00qf 5085 27 hair hair NN cord-022526-j9kg00qf 5085 28 . . . cord-022526-j9kg00qf 5086 1 88 88 CD cord-022526-j9kg00qf 5087 1 Enteroliths enterolith NNS cord-022526-j9kg00qf 5087 2 usually usually RB cord-022526-j9kg00qf 5087 3 are be VBP cord-022526-j9kg00qf 5087 4 found find VBN cord-022526-j9kg00qf 5087 5 in in IN cord-022526-j9kg00qf 5087 6 the the DT cord-022526-j9kg00qf 5087 7 right right JJ cord-022526-j9kg00qf 5087 8 dorsal dorsal JJ cord-022526-j9kg00qf 5087 9 and and CC cord-022526-j9kg00qf 5087 10 transverse transverse JJ cord-022526-j9kg00qf 5087 11 colons colon NNS cord-022526-j9kg00qf 5087 12 . . . cord-022526-j9kg00qf 5088 1 90 90 CD cord-022526-j9kg00qf 5089 1 Although although IN cord-022526-j9kg00qf 5089 2 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5089 3 has have VBZ cord-022526-j9kg00qf 5089 4 a a DT cord-022526-j9kg00qf 5089 5 wide wide JJ cord-022526-j9kg00qf 5089 6 geographic geographic JJ cord-022526-j9kg00qf 5089 7 distribution distribution NN cord-022526-j9kg00qf 5089 8 , , , cord-022526-j9kg00qf 5089 9 horses horse NNS cord-022526-j9kg00qf 5089 10 in in IN cord-022526-j9kg00qf 5089 11 California California NNP cord-022526-j9kg00qf 5089 12 have have VBP cord-022526-j9kg00qf 5089 13 the the DT cord-022526-j9kg00qf 5089 14 highest high JJS cord-022526-j9kg00qf 5089 15 incidence incidence NN cord-022526-j9kg00qf 5089 16 . . . cord-022526-j9kg00qf 5090 1 In in IN cord-022526-j9kg00qf 5090 2 one one CD cord-022526-j9kg00qf 5090 3 California California NNP cord-022526-j9kg00qf 5090 4 study study NN cord-022526-j9kg00qf 5090 5 , , , cord-022526-j9kg00qf 5090 6 horses horse NNS cord-022526-j9kg00qf 5090 7 with with IN cord-022526-j9kg00qf 5090 8 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5090 9 represented represent VBD cord-022526-j9kg00qf 5090 10 28 28 CD cord-022526-j9kg00qf 5090 11 % % NN cord-022526-j9kg00qf 5090 12 of of IN cord-022526-j9kg00qf 5090 13 the the DT cord-022526-j9kg00qf 5090 14 surgical surgical JJ cord-022526-j9kg00qf 5090 15 colic colic NN cord-022526-j9kg00qf 5090 16 population population NN cord-022526-j9kg00qf 5090 17 , , , cord-022526-j9kg00qf 5090 18 and and CC cord-022526-j9kg00qf 5090 19 Arabians Arabians NNPS cord-022526-j9kg00qf 5090 20 , , , cord-022526-j9kg00qf 5090 21 Morgans Morgans NNPS cord-022526-j9kg00qf 5090 22 , , , cord-022526-j9kg00qf 5090 23 American American NNP cord-022526-j9kg00qf 5090 24 Saddlebreds Saddlebreds NNP cord-022526-j9kg00qf 5090 25 , , , cord-022526-j9kg00qf 5090 26 and and CC cord-022526-j9kg00qf 5090 27 donkeys donkey NNS cord-022526-j9kg00qf 5090 28 were be VBD cord-022526-j9kg00qf 5090 29 at at IN cord-022526-j9kg00qf 5090 30 greatest great JJS cord-022526-j9kg00qf 5090 31 risk risk NN cord-022526-j9kg00qf 5090 32 of of IN cord-022526-j9kg00qf 5090 33 this this DT cord-022526-j9kg00qf 5090 34 disease disease NN cord-022526-j9kg00qf 5090 35 . . . cord-022526-j9kg00qf 5091 1 91 91 CD cord-022526-j9kg00qf 5092 1 In in IN cord-022526-j9kg00qf 5092 2 a a DT cord-022526-j9kg00qf 5092 3 study study NN cord-022526-j9kg00qf 5092 4 of of IN cord-022526-j9kg00qf 5092 5 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5092 6 in in IN cord-022526-j9kg00qf 5092 7 Texas Texas NNP cord-022526-j9kg00qf 5092 8 , , , cord-022526-j9kg00qf 5092 9 risk risk NN cord-022526-j9kg00qf 5092 10 factors factor NNS cord-022526-j9kg00qf 5092 11 also also RB cord-022526-j9kg00qf 5092 12 included include VBD cord-022526-j9kg00qf 5092 13 feeding feeding NN cord-022526-j9kg00qf 5092 14 of of IN cord-022526-j9kg00qf 5092 15 alfalfa alfalfa NN cord-022526-j9kg00qf 5092 16 hay hay NN cord-022526-j9kg00qf 5092 17 and and CC cord-022526-j9kg00qf 5092 18 Arabian arabian JJ cord-022526-j9kg00qf 5092 19 breed breed NN cord-022526-j9kg00qf 5092 20 . . . cord-022526-j9kg00qf 5093 1 However however RB cord-022526-j9kg00qf 5093 2 , , , cord-022526-j9kg00qf 5093 3 in in IN cord-022526-j9kg00qf 5093 4 that that DT cord-022526-j9kg00qf 5093 5 study study NN cord-022526-j9kg00qf 5093 6 , , , cord-022526-j9kg00qf 5093 7 miniature miniature JJ cord-022526-j9kg00qf 5093 8 horses horse NNS cord-022526-j9kg00qf 5093 9 were be VBD cord-022526-j9kg00qf 5093 10 also also RB cord-022526-j9kg00qf 5093 11 at at IN cord-022526-j9kg00qf 5093 12 risk risk NN cord-022526-j9kg00qf 5093 13 . . . cord-022526-j9kg00qf 5094 1 92 92 CD cord-022526-j9kg00qf 5094 2 Horses horse NNS cord-022526-j9kg00qf 5094 3 with with IN cord-022526-j9kg00qf 5094 4 enteroliths enterolith NNS cord-022526-j9kg00qf 5094 5 are be VBP cord-022526-j9kg00qf 5094 6 rarely rarely RB cord-022526-j9kg00qf 5094 7 under under IN cord-022526-j9kg00qf 5094 8 4 4 CD cord-022526-j9kg00qf 5094 9 years year NNS cord-022526-j9kg00qf 5094 10 old old JJ cord-022526-j9kg00qf 5094 11 , , , cord-022526-j9kg00qf 5094 12 90 90 CD cord-022526-j9kg00qf 5094 13 although although IN cord-022526-j9kg00qf 5094 14 an an DT cord-022526-j9kg00qf 5094 15 enterolith enterolith NN cord-022526-j9kg00qf 5094 16 in in IN cord-022526-j9kg00qf 5094 17 an an DT cord-022526-j9kg00qf 5094 18 11-month 11-month JJ cord-022526-j9kg00qf 5094 19 - - HYPH cord-022526-j9kg00qf 5094 20 old old JJ cord-022526-j9kg00qf 5094 21 miniature miniature JJ cord-022526-j9kg00qf 5094 22 horse horse NN cord-022526-j9kg00qf 5094 23 has have VBZ cord-022526-j9kg00qf 5094 24 been be VBN cord-022526-j9kg00qf 5094 25 reported report VBN cord-022526-j9kg00qf 5094 26 recently recently RB cord-022526-j9kg00qf 5094 27 . . . cord-022526-j9kg00qf 5095 1 93 93 CD cord-022526-j9kg00qf 5096 1 Enterolithiasis Enterolithiasis NNP cord-022526-j9kg00qf 5096 2 is be VBZ cord-022526-j9kg00qf 5096 3 characterized characterize VBN cord-022526-j9kg00qf 5096 4 by by IN cord-022526-j9kg00qf 5096 5 episodic episodic JJ cord-022526-j9kg00qf 5096 6 , , , cord-022526-j9kg00qf 5096 7 mild mild JJ cord-022526-j9kg00qf 5096 8 to to TO cord-022526-j9kg00qf 5096 9 moderate moderate JJ cord-022526-j9kg00qf 5096 10 , , , cord-022526-j9kg00qf 5096 11 intermittent intermittent JJ cord-022526-j9kg00qf 5096 12 abdominal abdominal JJ cord-022526-j9kg00qf 5096 13 pain pain NN cord-022526-j9kg00qf 5096 14 . . . cord-022526-j9kg00qf 5097 1 90 90 CD cord-022526-j9kg00qf 5097 2 Progressive progressive JJ cord-022526-j9kg00qf 5097 3 anorexia anorexia NN cord-022526-j9kg00qf 5097 4 and and CC cord-022526-j9kg00qf 5097 5 depression depression NN cord-022526-j9kg00qf 5097 6 may may MD cord-022526-j9kg00qf 5097 7 develop develop VB cord-022526-j9kg00qf 5097 8 . . . cord-022526-j9kg00qf 5098 1 The the DT cord-022526-j9kg00qf 5098 2 amount amount NN cord-022526-j9kg00qf 5098 3 of of IN cord-022526-j9kg00qf 5098 4 pain pain NN cord-022526-j9kg00qf 5098 5 depends depend VBZ cord-022526-j9kg00qf 5098 6 on on IN cord-022526-j9kg00qf 5098 7 the the DT cord-022526-j9kg00qf 5098 8 degree degree NN cord-022526-j9kg00qf 5098 9 of of IN cord-022526-j9kg00qf 5098 10 obstruction obstruction NN cord-022526-j9kg00qf 5098 11 and and CC cord-022526-j9kg00qf 5098 12 amount amount NN cord-022526-j9kg00qf 5098 13 of of IN cord-022526-j9kg00qf 5098 14 distention distention NN cord-022526-j9kg00qf 5098 15 . . . cord-022526-j9kg00qf 5099 1 Partial partial JJ cord-022526-j9kg00qf 5099 2 luminal luminal JJ cord-022526-j9kg00qf 5099 3 obstruction obstruction NN cord-022526-j9kg00qf 5099 4 allows allow VBZ cord-022526-j9kg00qf 5099 5 the the DT cord-022526-j9kg00qf 5099 6 passage passage NN cord-022526-j9kg00qf 5099 7 of of IN cord-022526-j9kg00qf 5099 8 scant scant JJ cord-022526-j9kg00qf 5099 9 , , , cord-022526-j9kg00qf 5099 10 pasty pasty JJ cord-022526-j9kg00qf 5099 11 feces fece NNS cord-022526-j9kg00qf 5099 12 . . . cord-022526-j9kg00qf 5100 1 Heart heart NN cord-022526-j9kg00qf 5100 2 rate rate NN cord-022526-j9kg00qf 5100 3 varies vary VBZ cord-022526-j9kg00qf 5100 4 and and CC cord-022526-j9kg00qf 5100 5 depends depend VBZ cord-022526-j9kg00qf 5100 6 on on IN cord-022526-j9kg00qf 5100 7 the the DT cord-022526-j9kg00qf 5100 8 degree degree NN cord-022526-j9kg00qf 5100 9 of of IN cord-022526-j9kg00qf 5100 10 pain pain NN cord-022526-j9kg00qf 5100 11 . . . cord-022526-j9kg00qf 5101 1 In in IN cord-022526-j9kg00qf 5101 2 some some DT cord-022526-j9kg00qf 5101 3 cases case NNS cord-022526-j9kg00qf 5101 4 , , , cord-022526-j9kg00qf 5101 5 an an DT cord-022526-j9kg00qf 5101 6 enterolith enterolith NN cord-022526-j9kg00qf 5101 7 is be VBZ cord-022526-j9kg00qf 5101 8 forced force VBN cord-022526-j9kg00qf 5101 9 into into IN cord-022526-j9kg00qf 5101 10 the the DT cord-022526-j9kg00qf 5101 11 small small JJ cord-022526-j9kg00qf 5101 12 colon colon NN cord-022526-j9kg00qf 5101 13 , , , cord-022526-j9kg00qf 5101 14 where where WRB cord-022526-j9kg00qf 5101 15 it -PRON- PRP cord-022526-j9kg00qf 5101 16 causes cause VBZ cord-022526-j9kg00qf 5101 17 acute acute JJ cord-022526-j9kg00qf 5101 18 small small JJ cord-022526-j9kg00qf 5101 19 colon colon NN cord-022526-j9kg00qf 5101 20 obstruction obstruction NN cord-022526-j9kg00qf 5101 21 . . . cord-022526-j9kg00qf 5102 1 One one CD cord-022526-j9kg00qf 5102 2 may may MD cord-022526-j9kg00qf 5102 3 diagnose diagnose VB cord-022526-j9kg00qf 5102 4 enteroliths enterolith NNS cord-022526-j9kg00qf 5102 5 by by IN cord-022526-j9kg00qf 5102 6 abdominal abdominal JJ cord-022526-j9kg00qf 5102 7 radiography radiography NN cord-022526-j9kg00qf 5102 8 or or CC cord-022526-j9kg00qf 5102 9 at at IN cord-022526-j9kg00qf 5102 10 surgery surgery NN cord-022526-j9kg00qf 5102 11 . . . cord-022526-j9kg00qf 5103 1 On on IN cord-022526-j9kg00qf 5103 2 rare rare JJ cord-022526-j9kg00qf 5103 3 occasions occasion NNS cord-022526-j9kg00qf 5103 4 , , , cord-022526-j9kg00qf 5103 5 one one PRP cord-022526-j9kg00qf 5103 6 may may MD cord-022526-j9kg00qf 5103 7 palpate palpate VB cord-022526-j9kg00qf 5103 8 an an DT cord-022526-j9kg00qf 5103 9 enterolith enterolith NN cord-022526-j9kg00qf 5103 10 per per IN cord-022526-j9kg00qf 5103 11 rectum rectum NN cord-022526-j9kg00qf 5103 12 , , , cord-022526-j9kg00qf 5103 13 particularly particularly RB cord-022526-j9kg00qf 5103 14 if if IN cord-022526-j9kg00qf 5103 15 it -PRON- PRP cord-022526-j9kg00qf 5103 16 is be VBZ cord-022526-j9kg00qf 5103 17 present present JJ cord-022526-j9kg00qf 5103 18 in in IN cord-022526-j9kg00qf 5103 19 the the DT cord-022526-j9kg00qf 5103 20 distal distal JJ cord-022526-j9kg00qf 5103 21 small small JJ cord-022526-j9kg00qf 5103 22 colon colon NN cord-022526-j9kg00qf 5103 23 . . . cord-022526-j9kg00qf 5104 1 In in IN cord-022526-j9kg00qf 5104 2 general general JJ cord-022526-j9kg00qf 5104 3 , , , cord-022526-j9kg00qf 5104 4 these these DT cord-022526-j9kg00qf 5104 5 cases case NNS cord-022526-j9kg00qf 5104 6 require require VBP cord-022526-j9kg00qf 5104 7 surgery surgery NN cord-022526-j9kg00qf 5104 8 , , , cord-022526-j9kg00qf 5104 9 although although IN cord-022526-j9kg00qf 5104 10 enteroliths enterolith NNS cord-022526-j9kg00qf 5104 11 being be VBG cord-022526-j9kg00qf 5104 12 retrieved retrieve VBN cord-022526-j9kg00qf 5104 13 per per IN cord-022526-j9kg00qf 5104 14 rectum rectum NN cord-022526-j9kg00qf 5104 15 have have VBP cord-022526-j9kg00qf 5104 16 been be VBN cord-022526-j9kg00qf 5104 17 reported report VBN cord-022526-j9kg00qf 5104 18 . . . cord-022526-j9kg00qf 5105 1 In in IN cord-022526-j9kg00qf 5105 2 fact fact NN cord-022526-j9kg00qf 5105 3 in in IN cord-022526-j9kg00qf 5105 4 one one CD cord-022526-j9kg00qf 5105 5 study study NN cord-022526-j9kg00qf 5105 6 , , , cord-022526-j9kg00qf 5105 7 14 14 CD cord-022526-j9kg00qf 5105 8 % % NN cord-022526-j9kg00qf 5105 9 of of IN cord-022526-j9kg00qf 5105 10 horses horse NNS cord-022526-j9kg00qf 5105 11 presented present VBN cord-022526-j9kg00qf 5105 12 for for IN cord-022526-j9kg00qf 5105 13 treatment treatment NN cord-022526-j9kg00qf 5105 14 of of IN cord-022526-j9kg00qf 5105 15 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5105 16 had have VBD cord-022526-j9kg00qf 5105 17 a a DT cord-022526-j9kg00qf 5105 18 history history NN cord-022526-j9kg00qf 5105 19 of of IN cord-022526-j9kg00qf 5105 20 passing pass VBG cord-022526-j9kg00qf 5105 21 an an DT cord-022526-j9kg00qf 5105 22 enterolith enterolith NN cord-022526-j9kg00qf 5105 23 in in IN cord-022526-j9kg00qf 5105 24 the the DT cord-022526-j9kg00qf 5105 25 feces fece NNS cord-022526-j9kg00qf 5105 26 . . . cord-022526-j9kg00qf 5106 1 However however RB cord-022526-j9kg00qf 5106 2 , , , cord-022526-j9kg00qf 5106 3 enteroliths enterolith NNS cord-022526-j9kg00qf 5106 4 typically typically RB cord-022526-j9kg00qf 5106 5 are be VBP cord-022526-j9kg00qf 5106 6 located locate VBN cord-022526-j9kg00qf 5106 7 in in IN cord-022526-j9kg00qf 5106 8 the the DT cord-022526-j9kg00qf 5106 9 right right JJ cord-022526-j9kg00qf 5106 10 dorsal dorsal JJ cord-022526-j9kg00qf 5106 11 colon colon NN cord-022526-j9kg00qf 5106 12 , , , cord-022526-j9kg00qf 5106 13 transverse transverse JJ cord-022526-j9kg00qf 5106 14 colon colon NN cord-022526-j9kg00qf 5106 15 , , , cord-022526-j9kg00qf 5106 16 or or CC cord-022526-j9kg00qf 5106 17 small small JJ cord-022526-j9kg00qf 5106 18 colon colon NN cord-022526-j9kg00qf 5106 19 . . . cord-022526-j9kg00qf 5107 1 At at IN cord-022526-j9kg00qf 5107 2 surgery surgery NN cord-022526-j9kg00qf 5107 3 , , , cord-022526-j9kg00qf 5107 4 one one CD cord-022526-j9kg00qf 5107 5 gently gently RB cord-022526-j9kg00qf 5107 6 pushes push VBZ cord-022526-j9kg00qf 5107 7 the the DT cord-022526-j9kg00qf 5107 8 enterolith enterolith NN cord-022526-j9kg00qf 5107 9 toward toward IN cord-022526-j9kg00qf 5107 10 a a DT cord-022526-j9kg00qf 5107 11 pelvic pelvic JJ cord-022526-j9kg00qf 5107 12 flexure flexure NN cord-022526-j9kg00qf 5107 13 enterotomy enterotomy NN cord-022526-j9kg00qf 5107 14 , , , cord-022526-j9kg00qf 5107 15 but but CC cord-022526-j9kg00qf 5107 16 removal removal NN cord-022526-j9kg00qf 5107 17 frequently frequently RB cord-022526-j9kg00qf 5107 18 requires require VBZ cord-022526-j9kg00qf 5107 19 a a DT cord-022526-j9kg00qf 5107 20 separate separate JJ cord-022526-j9kg00qf 5107 21 right right JJ cord-022526-j9kg00qf 5107 22 dorsal dorsal JJ cord-022526-j9kg00qf 5107 23 colon colon NN cord-022526-j9kg00qf 5107 24 enterotomy enterotomy NNP cord-022526-j9kg00qf 5107 25 to to TO cord-022526-j9kg00qf 5107 26 prevent prevent VB cord-022526-j9kg00qf 5107 27 rupture rupture NN cord-022526-j9kg00qf 5107 28 of of IN cord-022526-j9kg00qf 5107 29 the the DT cord-022526-j9kg00qf 5107 30 colon colon NN cord-022526-j9kg00qf 5107 31 . . . cord-022526-j9kg00qf 5108 1 Following follow VBG cord-022526-j9kg00qf 5108 2 removal removal NN cord-022526-j9kg00qf 5108 3 of of IN cord-022526-j9kg00qf 5108 4 an an DT cord-022526-j9kg00qf 5108 5 enterolith enterolith NN cord-022526-j9kg00qf 5108 6 , , , cord-022526-j9kg00qf 5108 7 one one PRP cord-022526-j9kg00qf 5108 8 must must MD cord-022526-j9kg00qf 5108 9 conduct conduct VB cord-022526-j9kg00qf 5108 10 further further JJ cord-022526-j9kg00qf 5108 11 exploration exploration NN cord-022526-j9kg00qf 5108 12 to to TO cord-022526-j9kg00qf 5108 13 determine determine VB cord-022526-j9kg00qf 5108 14 if if IN cord-022526-j9kg00qf 5108 15 other other JJ cord-022526-j9kg00qf 5108 16 enteroliths enterolith NNS cord-022526-j9kg00qf 5108 17 are be VBP cord-022526-j9kg00qf 5108 18 present present JJ cord-022526-j9kg00qf 5108 19 . . . cord-022526-j9kg00qf 5109 1 Solitary solitary JJ cord-022526-j9kg00qf 5109 2 enteroliths enterolith NNS cord-022526-j9kg00qf 5109 3 are be VBP cord-022526-j9kg00qf 5109 4 usually usually RB cord-022526-j9kg00qf 5109 5 round round JJ cord-022526-j9kg00qf 5109 6 , , , cord-022526-j9kg00qf 5109 7 whereas whereas IN cord-022526-j9kg00qf 5109 8 multiple multiple JJ cord-022526-j9kg00qf 5109 9 enteroliths enterolith NNS cord-022526-j9kg00qf 5109 10 have have VBP cord-022526-j9kg00qf 5109 11 flat flat JJ cord-022526-j9kg00qf 5109 12 sides side NNS cord-022526-j9kg00qf 5109 13 . . . cord-022526-j9kg00qf 5110 1 The the DT cord-022526-j9kg00qf 5110 2 prognosis prognosis NN cord-022526-j9kg00qf 5110 3 is be VBZ cord-022526-j9kg00qf 5110 4 good good JJ cord-022526-j9kg00qf 5110 5 ( ( -LRB- cord-022526-j9kg00qf 5110 6 92 92 CD cord-022526-j9kg00qf 5110 7 % % NN cord-022526-j9kg00qf 5110 8 1-year 1-year CD cord-022526-j9kg00qf 5110 9 survival survival NN cord-022526-j9kg00qf 5110 10 in in IN cord-022526-j9kg00qf 5110 11 one one CD cord-022526-j9kg00qf 5110 12 study study NN cord-022526-j9kg00qf 5110 13 of of IN cord-022526-j9kg00qf 5110 14 900 900 CD cord-022526-j9kg00qf 5110 15 cases case NNS cord-022526-j9kg00qf 5110 16 ) ) -RRB- cord-022526-j9kg00qf 5110 17 , , , cord-022526-j9kg00qf 5110 18 unless unless IN cord-022526-j9kg00qf 5110 19 the the DT cord-022526-j9kg00qf 5110 20 colon colon NN cord-022526-j9kg00qf 5110 21 ruptures rupture NNS cord-022526-j9kg00qf 5110 22 during during IN cord-022526-j9kg00qf 5110 23 removal removal NN cord-022526-j9kg00qf 5110 24 of of IN cord-022526-j9kg00qf 5110 25 an an DT cord-022526-j9kg00qf 5110 26 enterolith enterolith NN cord-022526-j9kg00qf 5110 27 . . . cord-022526-j9kg00qf 5111 1 In in IN cord-022526-j9kg00qf 5111 2 one one CD cord-022526-j9kg00qf 5111 3 recent recent JJ cord-022526-j9kg00qf 5111 4 study study NN cord-022526-j9kg00qf 5111 5 , , , cord-022526-j9kg00qf 5111 6 rupture rupture NN cord-022526-j9kg00qf 5111 7 occurred occur VBD cord-022526-j9kg00qf 5111 8 in in IN cord-022526-j9kg00qf 5111 9 15 15 CD cord-022526-j9kg00qf 5111 10 % % NN cord-022526-j9kg00qf 5111 11 of of IN cord-022526-j9kg00qf 5111 12 cases case NNS cord-022526-j9kg00qf 5111 13 . . . cord-022526-j9kg00qf 5112 1 91 91 CD cord-022526-j9kg00qf 5112 2 Sand sand NN cord-022526-j9kg00qf 5112 3 impactions impaction NNS cord-022526-j9kg00qf 5112 4 are be VBP cord-022526-j9kg00qf 5112 5 common common JJ cord-022526-j9kg00qf 5112 6 in in IN cord-022526-j9kg00qf 5112 7 horses horse NNS cord-022526-j9kg00qf 5112 8 with with IN cord-022526-j9kg00qf 5112 9 access access NN cord-022526-j9kg00qf 5112 10 to to IN cord-022526-j9kg00qf 5112 11 sandy sandy JJ cord-022526-j9kg00qf 5112 12 soils soil NNS cord-022526-j9kg00qf 5112 13 , , , cord-022526-j9kg00qf 5112 14 particularly particularly RB cord-022526-j9kg00qf 5112 15 horses horse NNS cord-022526-j9kg00qf 5112 16 eating eat VBG cord-022526-j9kg00qf 5112 17 feed feed NN cord-022526-j9kg00qf 5112 18 placed place VBN cord-022526-j9kg00qf 5112 19 on on IN cord-022526-j9kg00qf 5112 20 the the DT cord-022526-j9kg00qf 5112 21 ground ground NN cord-022526-j9kg00qf 5112 22 . . . cord-022526-j9kg00qf 5113 1 Some some DT cord-022526-j9kg00qf 5113 2 horses horse NNS cord-022526-j9kg00qf 5113 3 , , , cord-022526-j9kg00qf 5113 4 especially especially RB cord-022526-j9kg00qf 5113 5 foals foal NNS cord-022526-j9kg00qf 5113 6 , , , cord-022526-j9kg00qf 5113 7 deliberately deliberately RB cord-022526-j9kg00qf 5113 8 eat eat VB cord-022526-j9kg00qf 5113 9 sand sand NN cord-022526-j9kg00qf 5113 10 . . . cord-022526-j9kg00qf 5114 1 Fine fine JJ cord-022526-j9kg00qf 5114 2 sand sand NN cord-022526-j9kg00qf 5114 3 tends tend VBZ cord-022526-j9kg00qf 5114 4 to to TO cord-022526-j9kg00qf 5114 5 accumulate accumulate VB cord-022526-j9kg00qf 5114 6 in in IN cord-022526-j9kg00qf 5114 7 the the DT cord-022526-j9kg00qf 5114 8 ventral ventral JJ cord-022526-j9kg00qf 5114 9 colon colon NN cord-022526-j9kg00qf 5114 10 , , , cord-022526-j9kg00qf 5114 11 whereas whereas IN cord-022526-j9kg00qf 5114 12 coarse coarse JJ cord-022526-j9kg00qf 5114 13 sand sand NN cord-022526-j9kg00qf 5114 14 may may MD cord-022526-j9kg00qf 5114 15 accumulate accumulate VB cord-022526-j9kg00qf 5114 16 in in IN cord-022526-j9kg00qf 5114 17 the the DT cord-022526-j9kg00qf 5114 18 dorsal dorsal JJ cord-022526-j9kg00qf 5114 19 colon colon NN cord-022526-j9kg00qf 5114 20 . . . cord-022526-j9kg00qf 5115 1 94 94 CD cord-022526-j9kg00qf 5115 2 , , , cord-022526-j9kg00qf 5115 3 95 95 CD cord-022526-j9kg00qf 5116 1 However however RB cord-022526-j9kg00qf 5116 2 , , , cord-022526-j9kg00qf 5116 3 individual individual JJ cord-022526-j9kg00qf 5116 4 differences difference NNS cord-022526-j9kg00qf 5116 5 in in IN cord-022526-j9kg00qf 5116 6 colonic colonic JJ cord-022526-j9kg00qf 5116 7 function function NN cord-022526-j9kg00qf 5116 8 may may MD cord-022526-j9kg00qf 5116 9 contribute contribute VB cord-022526-j9kg00qf 5116 10 to to IN cord-022526-j9kg00qf 5116 11 accumulation accumulation NN cord-022526-j9kg00qf 5116 12 of of IN cord-022526-j9kg00qf 5116 13 sand sand NN cord-022526-j9kg00qf 5116 14 , , , cord-022526-j9kg00qf 5116 15 because because IN cord-022526-j9kg00qf 5116 16 some some DT cord-022526-j9kg00qf 5116 17 horses horse NNS cord-022526-j9kg00qf 5116 18 can can MD cord-022526-j9kg00qf 5116 19 clear clear VB cord-022526-j9kg00qf 5116 20 consumed consume VBN cord-022526-j9kg00qf 5116 21 sand sand NN cord-022526-j9kg00qf 5116 22 , , , cord-022526-j9kg00qf 5116 23 whereas whereas IN cord-022526-j9kg00qf 5116 24 others other NNS cord-022526-j9kg00qf 5116 25 can can MD cord-022526-j9kg00qf 5116 26 not not RB cord-022526-j9kg00qf 5116 27 . . . cord-022526-j9kg00qf 5117 1 Distention Distention NNP cord-022526-j9kg00qf 5117 2 from from IN cord-022526-j9kg00qf 5117 3 the the DT cord-022526-j9kg00qf 5117 4 impaction impaction NN cord-022526-j9kg00qf 5117 5 itself -PRON- PRP cord-022526-j9kg00qf 5117 6 , , , cord-022526-j9kg00qf 5117 7 or or CC cord-022526-j9kg00qf 5117 8 gas gas NN cord-022526-j9kg00qf 5117 9 proximal proximal JJ cord-022526-j9kg00qf 5117 10 to to IN cord-022526-j9kg00qf 5117 11 the the DT cord-022526-j9kg00qf 5117 12 impaction impaction NN cord-022526-j9kg00qf 5117 13 , , , cord-022526-j9kg00qf 5117 14 causes cause VBZ cord-022526-j9kg00qf 5117 15 abdominal abdominal JJ cord-022526-j9kg00qf 5117 16 pain pain NN cord-022526-j9kg00qf 5117 17 . . . cord-022526-j9kg00qf 5118 1 In in IN cord-022526-j9kg00qf 5118 2 addition addition NN cord-022526-j9kg00qf 5118 3 , , , cord-022526-j9kg00qf 5118 4 sand sand NN cord-022526-j9kg00qf 5118 5 may may MD cord-022526-j9kg00qf 5118 6 trigger trigger VB cord-022526-j9kg00qf 5118 7 diarrhea diarrhea NN cord-022526-j9kg00qf 5118 8 , , , cord-022526-j9kg00qf 5118 9 presumably presumably RB cord-022526-j9kg00qf 5118 10 because because IN cord-022526-j9kg00qf 5118 11 of of IN cord-022526-j9kg00qf 5118 12 irritation irritation NN cord-022526-j9kg00qf 5118 13 of of IN cord-022526-j9kg00qf 5118 14 the the DT cord-022526-j9kg00qf 5118 15 colonic colonic JJ cord-022526-j9kg00qf 5118 16 mucosa mucosa NN cord-022526-j9kg00qf 5118 17 . . . cord-022526-j9kg00qf 5119 1 96 96 CD cord-022526-j9kg00qf 5120 1 In in IN cord-022526-j9kg00qf 5120 2 horses horse NNS cord-022526-j9kg00qf 5120 3 with with IN cord-022526-j9kg00qf 5120 4 sand sand NN cord-022526-j9kg00qf 5120 5 impactions impaction NNS cord-022526-j9kg00qf 5120 6 , , , cord-022526-j9kg00qf 5120 7 clinical clinical JJ cord-022526-j9kg00qf 5120 8 signs sign NNS cord-022526-j9kg00qf 5120 9 are be VBP cord-022526-j9kg00qf 5120 10 similar similar JJ cord-022526-j9kg00qf 5120 11 to to IN cord-022526-j9kg00qf 5120 12 those those DT cord-022526-j9kg00qf 5120 13 of of IN cord-022526-j9kg00qf 5120 14 horses horse NNS cord-022526-j9kg00qf 5120 15 with with IN cord-022526-j9kg00qf 5120 16 large large JJ cord-022526-j9kg00qf 5120 17 colon colon NN cord-022526-j9kg00qf 5120 18 impactions impaction NNS cord-022526-j9kg00qf 5120 19 . . . cord-022526-j9kg00qf 5121 1 94 94 CD cord-022526-j9kg00qf 5122 1 One one PRP cord-022526-j9kg00qf 5122 2 may may MD cord-022526-j9kg00qf 5122 3 find find VB cord-022526-j9kg00qf 5122 4 sand sand NN cord-022526-j9kg00qf 5122 5 in in IN cord-022526-j9kg00qf 5122 6 the the DT cord-022526-j9kg00qf 5122 7 feces fece NNS cord-022526-j9kg00qf 5122 8 , , , cord-022526-j9kg00qf 5122 9 and and CC cord-022526-j9kg00qf 5122 10 auscultation auscultation NN cord-022526-j9kg00qf 5122 11 of of IN cord-022526-j9kg00qf 5122 12 the the DT cord-022526-j9kg00qf 5122 13 ventral ventral JJ cord-022526-j9kg00qf 5122 14 abdomen abdomen NN cord-022526-j9kg00qf 5122 15 may may MD cord-022526-j9kg00qf 5122 16 reveal reveal VB cord-022526-j9kg00qf 5122 17 sounds sound NNS cord-022526-j9kg00qf 5122 18 of of IN cord-022526-j9kg00qf 5122 19 sand sand NN cord-022526-j9kg00qf 5122 20 moving move VBG cord-022526-j9kg00qf 5122 21 within within IN cord-022526-j9kg00qf 5122 22 the the DT cord-022526-j9kg00qf 5122 23 large large JJ cord-022526-j9kg00qf 5122 24 colon colon NN cord-022526-j9kg00qf 5122 25 . . . cord-022526-j9kg00qf 5123 1 97 97 CD cord-022526-j9kg00qf 5124 1 However however RB cord-022526-j9kg00qf 5124 2 , , , cord-022526-j9kg00qf 5124 3 unlike unlike IN cord-022526-j9kg00qf 5124 4 sand sand NN cord-022526-j9kg00qf 5124 5 - - HYPH cord-022526-j9kg00qf 5124 6 induced induce VBN cord-022526-j9kg00qf 5124 7 diarrhea diarrhea NN cord-022526-j9kg00qf 5124 8 , , , cord-022526-j9kg00qf 5124 9 one one PRP cord-022526-j9kg00qf 5124 10 may may MD cord-022526-j9kg00qf 5124 11 not not RB cord-022526-j9kg00qf 5124 12 hear hear VB cord-022526-j9kg00qf 5124 13 sand sand NN cord-022526-j9kg00qf 5124 14 impactions impaction NNS cord-022526-j9kg00qf 5124 15 easily easily RB cord-022526-j9kg00qf 5124 16 because because IN cord-022526-j9kg00qf 5124 17 of of IN cord-022526-j9kg00qf 5124 18 the the DT cord-022526-j9kg00qf 5124 19 lack lack NN cord-022526-j9kg00qf 5124 20 of of IN cord-022526-j9kg00qf 5124 21 colonic colonic JJ cord-022526-j9kg00qf 5124 22 motility motility NN cord-022526-j9kg00qf 5124 23 . . . cord-022526-j9kg00qf 5125 1 To to TO cord-022526-j9kg00qf 5125 2 determine determine VB cord-022526-j9kg00qf 5125 3 the the DT cord-022526-j9kg00qf 5125 4 presence presence NN cord-022526-j9kg00qf 5125 5 of of IN cord-022526-j9kg00qf 5125 6 fecal fecal JJ cord-022526-j9kg00qf 5125 7 sand sand NN cord-022526-j9kg00qf 5125 8 , , , cord-022526-j9kg00qf 5125 9 one one CD cord-022526-j9kg00qf 5125 10 places place VBZ cord-022526-j9kg00qf 5125 11 several several JJ cord-022526-j9kg00qf 5125 12 fecal fecal JJ cord-022526-j9kg00qf 5125 13 balls ball NNS cord-022526-j9kg00qf 5125 14 in in IN cord-022526-j9kg00qf 5125 15 a a DT cord-022526-j9kg00qf 5125 16 rectal rectal JJ cord-022526-j9kg00qf 5125 17 palpation palpation NN cord-022526-j9kg00qf 5125 18 sleeve sleeve NN cord-022526-j9kg00qf 5125 19 or or CC cord-022526-j9kg00qf 5125 20 other other JJ cord-022526-j9kg00qf 5125 21 container container NN cord-022526-j9kg00qf 5125 22 , , , cord-022526-j9kg00qf 5125 23 which which WDT cord-022526-j9kg00qf 5125 24 subsequently subsequently RB cord-022526-j9kg00qf 5125 25 is be VBZ cord-022526-j9kg00qf 5125 26 filled fill VBN cord-022526-j9kg00qf 5125 27 with with IN cord-022526-j9kg00qf 5125 28 water water NN cord-022526-j9kg00qf 5125 29 . . . cord-022526-j9kg00qf 5126 1 If if IN cord-022526-j9kg00qf 5126 2 sand sand NN cord-022526-j9kg00qf 5126 3 is be VBZ cord-022526-j9kg00qf 5126 4 present present JJ cord-022526-j9kg00qf 5126 5 , , , cord-022526-j9kg00qf 5126 6 it -PRON- PRP cord-022526-j9kg00qf 5126 7 accumulates accumulate VBZ cord-022526-j9kg00qf 5126 8 at at IN cord-022526-j9kg00qf 5126 9 the the DT cord-022526-j9kg00qf 5126 10 bottom bottom NN cord-022526-j9kg00qf 5126 11 of of IN cord-022526-j9kg00qf 5126 12 the the DT cord-022526-j9kg00qf 5126 13 container container NN cord-022526-j9kg00qf 5126 14 . . . cord-022526-j9kg00qf 5127 1 In in IN cord-022526-j9kg00qf 5127 2 addition addition NN cord-022526-j9kg00qf 5127 3 , , , cord-022526-j9kg00qf 5127 4 one one PRP cord-022526-j9kg00qf 5127 5 may may MD cord-022526-j9kg00qf 5127 6 detect detect VB cord-022526-j9kg00qf 5127 7 mineral mineral NN cord-022526-j9kg00qf 5127 8 opacity opacity NN cord-022526-j9kg00qf 5127 9 within within IN cord-022526-j9kg00qf 5127 10 the the DT cord-022526-j9kg00qf 5127 11 colon colon NN cord-022526-j9kg00qf 5127 12 on on IN cord-022526-j9kg00qf 5127 13 abdominal abdominal JJ cord-022526-j9kg00qf 5127 14 radiographs radiograph NNS cord-022526-j9kg00qf 5127 15 , , , cord-022526-j9kg00qf 5127 16 particularly particularly RB cord-022526-j9kg00qf 5127 17 in in IN cord-022526-j9kg00qf 5127 18 foals foal NNS cord-022526-j9kg00qf 5127 19 , , , cord-022526-j9kg00qf 5127 20 ponies pony NNS cord-022526-j9kg00qf 5127 21 , , , cord-022526-j9kg00qf 5127 22 and and CC cord-022526-j9kg00qf 5127 23 small small JJ cord-022526-j9kg00qf 5127 24 horses horse NNS cord-022526-j9kg00qf 5127 25 . . . cord-022526-j9kg00qf 5128 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5128 2 paracentesis paracentesi NNS cord-022526-j9kg00qf 5128 3 typically typically RB cord-022526-j9kg00qf 5128 4 yields yield VBZ cord-022526-j9kg00qf 5128 5 normal normal JJ cord-022526-j9kg00qf 5128 6 fluid fluid NN cord-022526-j9kg00qf 5128 7 and and CC cord-022526-j9kg00qf 5128 8 poses pose VBZ cord-022526-j9kg00qf 5128 9 some some DT cord-022526-j9kg00qf 5128 10 risk risk NN cord-022526-j9kg00qf 5128 11 because because IN cord-022526-j9kg00qf 5128 12 large large JJ cord-022526-j9kg00qf 5128 13 quantities quantity NNS cord-022526-j9kg00qf 5128 14 of of IN cord-022526-j9kg00qf 5128 15 sand sand NN cord-022526-j9kg00qf 5128 16 in in IN cord-022526-j9kg00qf 5128 17 the the DT cord-022526-j9kg00qf 5128 18 ventral ventral JJ cord-022526-j9kg00qf 5128 19 colon colon NN cord-022526-j9kg00qf 5128 20 make make VB cord-022526-j9kg00qf 5128 21 inadvertent inadvertent JJ cord-022526-j9kg00qf 5128 22 perforation perforation NN cord-022526-j9kg00qf 5128 23 of of IN cord-022526-j9kg00qf 5128 24 the the DT cord-022526-j9kg00qf 5128 25 colon colon NN cord-022526-j9kg00qf 5128 26 more more RBR cord-022526-j9kg00qf 5128 27 likely likely JJ cord-022526-j9kg00qf 5128 28 . . . cord-022526-j9kg00qf 5129 1 95 95 CD cord-022526-j9kg00qf 5129 2 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5129 3 fluid fluid NN cord-022526-j9kg00qf 5129 4 is be VBZ cord-022526-j9kg00qf 5129 5 often often RB cord-022526-j9kg00qf 5129 6 normal normal JJ cord-022526-j9kg00qf 5129 7 but but CC cord-022526-j9kg00qf 5129 8 may may MD cord-022526-j9kg00qf 5129 9 have have VB cord-022526-j9kg00qf 5129 10 an an DT cord-022526-j9kg00qf 5129 11 elevated elevated JJ cord-022526-j9kg00qf 5129 12 protein protein NN cord-022526-j9kg00qf 5129 13 concentration concentration NN cord-022526-j9kg00qf 5129 14 . . . cord-022526-j9kg00qf 5130 1 Initially initially RB cord-022526-j9kg00qf 5130 2 , , , cord-022526-j9kg00qf 5130 3 medical medical JJ cord-022526-j9kg00qf 5130 4 therapy therapy NN cord-022526-j9kg00qf 5130 5 is be VBZ cord-022526-j9kg00qf 5130 6 warranted warrant VBN cord-022526-j9kg00qf 5130 7 . . . cord-022526-j9kg00qf 5131 1 Administration administration NN cord-022526-j9kg00qf 5131 2 of of IN cord-022526-j9kg00qf 5131 3 psyllium psyllium NN cord-022526-j9kg00qf 5131 4 hydrophilic hydrophilic JJ cord-022526-j9kg00qf 5131 5 mucilloid mucilloid NNP cord-022526-j9kg00qf 5131 6 ( ( -LRB- cord-022526-j9kg00qf 5131 7 0.25 0.25 CD cord-022526-j9kg00qf 5131 8 to to IN cord-022526-j9kg00qf 5131 9 0.5 0.5 CD cord-022526-j9kg00qf 5131 10 kg/500 kg/500 NNP cord-022526-j9kg00qf 5131 11 kg kg NNS cord-022526-j9kg00qf 5131 12 in in IN cord-022526-j9kg00qf 5131 13 4 4 CD cord-022526-j9kg00qf 5131 14 to to TO cord-022526-j9kg00qf 5131 15 8 8 CD cord-022526-j9kg00qf 5131 16 L l NN cord-022526-j9kg00qf 5131 17 of of IN cord-022526-j9kg00qf 5131 18 water water NN cord-022526-j9kg00qf 5131 19 by by IN cord-022526-j9kg00qf 5131 20 stomach stomach NN cord-022526-j9kg00qf 5131 21 tube tube NN cord-022526-j9kg00qf 5131 22 ) ) -RRB- cord-022526-j9kg00qf 5131 23 may may MD cord-022526-j9kg00qf 5131 24 facilitate facilitate VB cord-022526-j9kg00qf 5131 25 passage passage NN cord-022526-j9kg00qf 5131 26 of of IN cord-022526-j9kg00qf 5131 27 sand sand NN cord-022526-j9kg00qf 5131 28 . . . cord-022526-j9kg00qf 5132 1 One one PRP cord-022526-j9kg00qf 5132 2 should should MD cord-022526-j9kg00qf 5132 3 administer administer VB cord-022526-j9kg00qf 5132 4 the the DT cord-022526-j9kg00qf 5132 5 solution solution NN cord-022526-j9kg00qf 5132 6 rapidly rapidly RB cord-022526-j9kg00qf 5132 7 because because IN cord-022526-j9kg00qf 5132 8 it -PRON- PRP cord-022526-j9kg00qf 5132 9 will will MD cord-022526-j9kg00qf 5132 10 form form VB cord-022526-j9kg00qf 5132 11 a a DT cord-022526-j9kg00qf 5132 12 viscous viscous JJ cord-022526-j9kg00qf 5132 13 gel gel NN cord-022526-j9kg00qf 5132 14 . . . cord-022526-j9kg00qf 5133 1 An an DT cord-022526-j9kg00qf 5133 2 alternative alternative JJ cord-022526-j9kg00qf 5133 3 method method NN cord-022526-j9kg00qf 5133 4 of of IN cord-022526-j9kg00qf 5133 5 administration administration NN cord-022526-j9kg00qf 5133 6 is be VBZ cord-022526-j9kg00qf 5133 7 to to TO cord-022526-j9kg00qf 5133 8 mix mix VB cord-022526-j9kg00qf 5133 9 psyllium psyllium NN cord-022526-j9kg00qf 5133 10 with with IN cord-022526-j9kg00qf 5133 11 2 2 CD cord-022526-j9kg00qf 5133 12 L l NN cord-022526-j9kg00qf 5133 13 of of IN cord-022526-j9kg00qf 5133 14 mineral mineral NN cord-022526-j9kg00qf 5133 15 oil oil NN cord-022526-j9kg00qf 5133 16 , , , cord-022526-j9kg00qf 5133 17 which which WDT cord-022526-j9kg00qf 5133 18 will will MD cord-022526-j9kg00qf 5133 19 not not RB cord-022526-j9kg00qf 5133 20 form form VB cord-022526-j9kg00qf 5133 21 a a DT cord-022526-j9kg00qf 5133 22 gel gel NN cord-022526-j9kg00qf 5133 23 and and CC cord-022526-j9kg00qf 5133 24 can can MD cord-022526-j9kg00qf 5133 25 be be VB cord-022526-j9kg00qf 5133 26 pumped pump VBN cord-022526-j9kg00qf 5133 27 through through IN cord-022526-j9kg00qf 5133 28 a a DT cord-022526-j9kg00qf 5133 29 nasogastric nasogastric NN cord-022526-j9kg00qf 5133 30 tube tube NN cord-022526-j9kg00qf 5133 31 easily easily RB cord-022526-j9kg00qf 5133 32 . . . cord-022526-j9kg00qf 5134 1 One one CD cord-022526-j9kg00qf 5134 2 then then RB cord-022526-j9kg00qf 5134 3 pumps pump VBZ cord-022526-j9kg00qf 5134 4 2 2 CD cord-022526-j9kg00qf 5134 5 to to IN cord-022526-j9kg00qf 5134 6 4 4 CD cord-022526-j9kg00qf 5134 7 L l NN cord-022526-j9kg00qf 5134 8 of of IN cord-022526-j9kg00qf 5134 9 water water NN cord-022526-j9kg00qf 5134 10 through through IN cord-022526-j9kg00qf 5134 11 the the DT cord-022526-j9kg00qf 5134 12 tube tube NN cord-022526-j9kg00qf 5134 13 . . . cord-022526-j9kg00qf 5135 1 The the DT cord-022526-j9kg00qf 5135 2 psyllium psyllium NN cord-022526-j9kg00qf 5135 3 separates separate VBZ cord-022526-j9kg00qf 5135 4 from from IN cord-022526-j9kg00qf 5135 5 the the DT cord-022526-j9kg00qf 5135 6 oil oil NN cord-022526-j9kg00qf 5135 7 phase phase NN cord-022526-j9kg00qf 5135 8 and and CC cord-022526-j9kg00qf 5135 9 mixes mix VBZ cord-022526-j9kg00qf 5135 10 with with IN cord-022526-j9kg00qf 5135 11 the the DT cord-022526-j9kg00qf 5135 12 water water NN cord-022526-j9kg00qf 5135 13 , , , cord-022526-j9kg00qf 5135 14 forming form VBG cord-022526-j9kg00qf 5135 15 a a DT cord-022526-j9kg00qf 5135 16 gel gel NN cord-022526-j9kg00qf 5135 17 within within IN cord-022526-j9kg00qf 5135 18 the the DT cord-022526-j9kg00qf 5135 19 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5135 20 tract tract NN cord-022526-j9kg00qf 5135 21 . . . cord-022526-j9kg00qf 5136 1 Psyllium psyllium NN cord-022526-j9kg00qf 5136 2 is be VBZ cord-022526-j9kg00qf 5136 3 thought think VBN cord-022526-j9kg00qf 5136 4 to to TO cord-022526-j9kg00qf 5136 5 act act VB cord-022526-j9kg00qf 5136 6 by by IN cord-022526-j9kg00qf 5136 7 stimulating stimulate VBG cord-022526-j9kg00qf 5136 8 motility motility NN cord-022526-j9kg00qf 5136 9 or or CC cord-022526-j9kg00qf 5136 10 by by IN cord-022526-j9kg00qf 5136 11 agglutinating agglutinate VBG cord-022526-j9kg00qf 5136 12 the the DT cord-022526-j9kg00qf 5136 13 sand sand NN cord-022526-j9kg00qf 5136 14 . . . cord-022526-j9kg00qf 5137 1 However however RB cord-022526-j9kg00qf 5137 2 , , , cord-022526-j9kg00qf 5137 3 a a DT cord-022526-j9kg00qf 5137 4 recent recent JJ cord-022526-j9kg00qf 5137 5 experimental experimental JJ cord-022526-j9kg00qf 5137 6 study study NN cord-022526-j9kg00qf 5137 7 failed fail VBD cord-022526-j9kg00qf 5137 8 to to TO cord-022526-j9kg00qf 5137 9 show show VB cord-022526-j9kg00qf 5137 10 a a DT cord-022526-j9kg00qf 5137 11 benefit benefit NN cord-022526-j9kg00qf 5137 12 of of IN cord-022526-j9kg00qf 5137 13 this this DT cord-022526-j9kg00qf 5137 14 treatment treatment NN cord-022526-j9kg00qf 5137 15 for for IN cord-022526-j9kg00qf 5137 16 clearing clear VBG cord-022526-j9kg00qf 5137 17 sand sand NN cord-022526-j9kg00qf 5137 18 from from IN cord-022526-j9kg00qf 5137 19 the the DT cord-022526-j9kg00qf 5137 20 colons colon NNS cord-022526-j9kg00qf 5137 21 of of IN cord-022526-j9kg00qf 5137 22 otherwise otherwise RB cord-022526-j9kg00qf 5137 23 normal normal JJ cord-022526-j9kg00qf 5137 24 horses horse NNS cord-022526-j9kg00qf 5137 25 . . . cord-022526-j9kg00qf 5138 1 98 98 CD cord-022526-j9kg00qf 5139 1 If if IN cord-022526-j9kg00qf 5139 2 a a DT cord-022526-j9kg00qf 5139 3 severe severe JJ cord-022526-j9kg00qf 5139 4 impaction impaction NN cord-022526-j9kg00qf 5139 5 is be VBZ cord-022526-j9kg00qf 5139 6 present present JJ cord-022526-j9kg00qf 5139 7 , , , cord-022526-j9kg00qf 5139 8 one one PRP cord-022526-j9kg00qf 5139 9 should should MD cord-022526-j9kg00qf 5139 10 not not RB cord-022526-j9kg00qf 5139 11 give give VB cord-022526-j9kg00qf 5139 12 the the DT cord-022526-j9kg00qf 5139 13 psyllium psyllium NN cord-022526-j9kg00qf 5139 14 until until IN cord-022526-j9kg00qf 5139 15 softening soften VBG cord-022526-j9kg00qf 5139 16 the the DT cord-022526-j9kg00qf 5139 17 impaction impaction NN cord-022526-j9kg00qf 5139 18 by by IN cord-022526-j9kg00qf 5139 19 administrating administrate VBG cord-022526-j9kg00qf 5139 20 intravenous intravenous JJ cord-022526-j9kg00qf 5139 21 or or CC cord-022526-j9kg00qf 5139 22 oral oral JJ cord-022526-j9kg00qf 5139 23 fluids fluid NNS cord-022526-j9kg00qf 5139 24 and and CC cord-022526-j9kg00qf 5139 25 other other JJ cord-022526-j9kg00qf 5139 26 laxatives laxative NNS cord-022526-j9kg00qf 5139 27 . . . cord-022526-j9kg00qf 5140 1 Perforation perforation NN cord-022526-j9kg00qf 5140 2 is be VBZ cord-022526-j9kg00qf 5140 3 a a DT cord-022526-j9kg00qf 5140 4 potential potential JJ cord-022526-j9kg00qf 5140 5 complication complication NN cord-022526-j9kg00qf 5140 6 in in IN cord-022526-j9kg00qf 5140 7 horses horse NNS cord-022526-j9kg00qf 5140 8 with with IN cord-022526-j9kg00qf 5140 9 sand sand NN cord-022526-j9kg00qf 5140 10 impactions impaction NNS cord-022526-j9kg00qf 5140 11 because because IN cord-022526-j9kg00qf 5140 12 the the DT cord-022526-j9kg00qf 5140 13 sand sand NN cord-022526-j9kg00qf 5140 14 stretches stretch VBZ cord-022526-j9kg00qf 5140 15 and and CC cord-022526-j9kg00qf 5140 16 irritates irritate VBZ cord-022526-j9kg00qf 5140 17 the the DT cord-022526-j9kg00qf 5140 18 intestinal intestinal JJ cord-022526-j9kg00qf 5140 19 wall wall NN cord-022526-j9kg00qf 5140 20 and and CC cord-022526-j9kg00qf 5140 21 causes cause VBZ cord-022526-j9kg00qf 5140 22 inflammation inflammation NN cord-022526-j9kg00qf 5140 23 . . . cord-022526-j9kg00qf 5141 1 Therefore therefore RB cord-022526-j9kg00qf 5141 2 if if IN cord-022526-j9kg00qf 5141 3 colic colic NN cord-022526-j9kg00qf 5141 4 becomes become VBZ cord-022526-j9kg00qf 5141 5 intractable intractable JJ cord-022526-j9kg00qf 5141 6 , , , cord-022526-j9kg00qf 5141 7 one one PRP cord-022526-j9kg00qf 5141 8 should should MD cord-022526-j9kg00qf 5141 9 perform perform VB cord-022526-j9kg00qf 5141 10 surgical surgical JJ cord-022526-j9kg00qf 5141 11 evacuation evacuation NN cord-022526-j9kg00qf 5141 12 of of IN cord-022526-j9kg00qf 5141 13 the the DT cord-022526-j9kg00qf 5141 14 large large JJ cord-022526-j9kg00qf 5141 15 colon colon NN cord-022526-j9kg00qf 5141 16 . . . cord-022526-j9kg00qf 5142 1 The the DT cord-022526-j9kg00qf 5142 2 prognosis prognosis NN cord-022526-j9kg00qf 5142 3 is be VBZ cord-022526-j9kg00qf 5142 4 generally generally RB cord-022526-j9kg00qf 5142 5 good good JJ cord-022526-j9kg00qf 5142 6 . . . cord-022526-j9kg00qf 5143 1 94 94 CD cord-022526-j9kg00qf 5143 2 , , , cord-022526-j9kg00qf 5143 3 95 95 CD cord-022526-j9kg00qf 5143 4 _SP cord-022526-j9kg00qf 5143 5 Displacement displacement NN cord-022526-j9kg00qf 5143 6 of of IN cord-022526-j9kg00qf 5143 7 the the DT cord-022526-j9kg00qf 5143 8 ascending ascend VBG cord-022526-j9kg00qf 5143 9 colon colon NN cord-022526-j9kg00qf 5143 10 is be VBZ cord-022526-j9kg00qf 5143 11 a a DT cord-022526-j9kg00qf 5143 12 common common JJ cord-022526-j9kg00qf 5143 13 cause cause NN cord-022526-j9kg00qf 5143 14 of of IN cord-022526-j9kg00qf 5143 15 large large JJ cord-022526-j9kg00qf 5143 16 intestinal intestinal JJ cord-022526-j9kg00qf 5143 17 obstruction obstruction NN cord-022526-j9kg00qf 5143 18 . . . cord-022526-j9kg00qf 5144 1 The the DT cord-022526-j9kg00qf 5144 2 ascending ascend VBG cord-022526-j9kg00qf 5144 3 colon colon NN cord-022526-j9kg00qf 5144 4 is be VBZ cord-022526-j9kg00qf 5144 5 freely freely RB cord-022526-j9kg00qf 5144 6 movable movable JJ cord-022526-j9kg00qf 5144 7 except except IN cord-022526-j9kg00qf 5144 8 for for IN cord-022526-j9kg00qf 5144 9 the the DT cord-022526-j9kg00qf 5144 10 right right JJ cord-022526-j9kg00qf 5144 11 dorsal dorsal JJ cord-022526-j9kg00qf 5144 12 and and CC cord-022526-j9kg00qf 5144 13 ventral ventral JJ cord-022526-j9kg00qf 5144 14 colons colon NNS cord-022526-j9kg00qf 5144 15 . . . cord-022526-j9kg00qf 5145 1 Contact contact NN cord-022526-j9kg00qf 5145 2 with with IN cord-022526-j9kg00qf 5145 3 adjacent adjacent JJ cord-022526-j9kg00qf 5145 4 viscera viscera NN cord-022526-j9kg00qf 5145 5 and and CC cord-022526-j9kg00qf 5145 6 the the DT cord-022526-j9kg00qf 5145 7 abdominal abdominal JJ cord-022526-j9kg00qf 5145 8 wall wall NN cord-022526-j9kg00qf 5145 9 tends tend VBZ cord-022526-j9kg00qf 5145 10 to to TO cord-022526-j9kg00qf 5145 11 inhibit inhibit VB cord-022526-j9kg00qf 5145 12 movement movement NN cord-022526-j9kg00qf 5145 13 of of IN cord-022526-j9kg00qf 5145 14 the the DT cord-022526-j9kg00qf 5145 15 ascending ascend VBG cord-022526-j9kg00qf 5145 16 colon colon NN cord-022526-j9kg00qf 5145 17 from from IN cord-022526-j9kg00qf 5145 18 a a DT cord-022526-j9kg00qf 5145 19 normal normal JJ cord-022526-j9kg00qf 5145 20 position position NN cord-022526-j9kg00qf 5145 21 ; ; : cord-022526-j9kg00qf 5145 22 however however RB cord-022526-j9kg00qf 5145 23 , , , cord-022526-j9kg00qf 5145 24 accumulation accumulation NN cord-022526-j9kg00qf 5145 25 of of IN cord-022526-j9kg00qf 5145 26 gas gas NN cord-022526-j9kg00qf 5145 27 and and CC cord-022526-j9kg00qf 5145 28 fluid fluid NN cord-022526-j9kg00qf 5145 29 or or CC cord-022526-j9kg00qf 5145 30 ingesta ingesta NNS cord-022526-j9kg00qf 5145 31 may may MD cord-022526-j9kg00qf 5145 32 cause cause VB cord-022526-j9kg00qf 5145 33 the the DT cord-022526-j9kg00qf 5145 34 colon colon NN cord-022526-j9kg00qf 5145 35 to to TO cord-022526-j9kg00qf 5145 36 migrate migrate VB cord-022526-j9kg00qf 5145 37 . . . cord-022526-j9kg00qf 5146 1 99 99 CD cord-022526-j9kg00qf 5146 2 Feeding feeding NN cord-022526-j9kg00qf 5146 3 practices practice NNS cord-022526-j9kg00qf 5146 4 , , , cord-022526-j9kg00qf 5146 5 including include VBG cord-022526-j9kg00qf 5146 6 feeding feeding NN cord-022526-j9kg00qf 5146 7 of of IN cord-022526-j9kg00qf 5146 8 large large JJ cord-022526-j9kg00qf 5146 9 concentrate concentrate NN cord-022526-j9kg00qf 5146 10 meals meal NNS cord-022526-j9kg00qf 5146 11 , , , cord-022526-j9kg00qf 5146 12 likely likely RB cord-022526-j9kg00qf 5146 13 plays play VBZ cord-022526-j9kg00qf 5146 14 a a DT cord-022526-j9kg00qf 5146 15 role role NN cord-022526-j9kg00qf 5146 16 in in IN cord-022526-j9kg00qf 5146 17 initiating initiate VBG cord-022526-j9kg00qf 5146 18 displacement displacement NN cord-022526-j9kg00qf 5146 19 of of IN cord-022526-j9kg00qf 5146 20 the the DT cord-022526-j9kg00qf 5146 21 large large JJ cord-022526-j9kg00qf 5146 22 colon colon NN cord-022526-j9kg00qf 5146 23 . . . cord-022526-j9kg00qf 5147 1 Large large JJ cord-022526-j9kg00qf 5147 2 concentrate concentrate NN cord-022526-j9kg00qf 5147 3 meals meal NNS cord-022526-j9kg00qf 5147 4 increase increase VBP cord-022526-j9kg00qf 5147 5 the the DT cord-022526-j9kg00qf 5147 6 rate rate NN cord-022526-j9kg00qf 5147 7 of of IN cord-022526-j9kg00qf 5147 8 passage passage NN cord-022526-j9kg00qf 5147 9 of of IN cord-022526-j9kg00qf 5147 10 ingesta ingesta NNP cord-022526-j9kg00qf 5147 11 , , , cord-022526-j9kg00qf 5147 12 allowing allow VBG cord-022526-j9kg00qf 5147 13 a a DT cord-022526-j9kg00qf 5147 14 greater great JJR cord-022526-j9kg00qf 5147 15 percentage percentage NN cord-022526-j9kg00qf 5147 16 of of IN cord-022526-j9kg00qf 5147 17 soluble soluble JJ cord-022526-j9kg00qf 5147 18 carbohydrates carbohydrate NNS cord-022526-j9kg00qf 5147 19 to to TO cord-022526-j9kg00qf 5147 20 reach reach VB cord-022526-j9kg00qf 5147 21 the the DT cord-022526-j9kg00qf 5147 22 large large JJ cord-022526-j9kg00qf 5147 23 intestine intestine NN cord-022526-j9kg00qf 5147 24 , , , cord-022526-j9kg00qf 5147 25 31 31 CD cord-022526-j9kg00qf 5147 26 which which WDT cord-022526-j9kg00qf 5147 27 in in IN cord-022526-j9kg00qf 5147 28 turn turn NN cord-022526-j9kg00qf 5147 29 increases increase VBZ cord-022526-j9kg00qf 5147 30 the the DT cord-022526-j9kg00qf 5147 31 rate rate NN cord-022526-j9kg00qf 5147 32 of of IN cord-022526-j9kg00qf 5147 33 fermentation fermentation NN cord-022526-j9kg00qf 5147 34 and and CC cord-022526-j9kg00qf 5147 35 the the DT cord-022526-j9kg00qf 5147 36 amount amount NN cord-022526-j9kg00qf 5147 37 of of IN cord-022526-j9kg00qf 5147 38 gas gas NN cord-022526-j9kg00qf 5147 39 and and CC cord-022526-j9kg00qf 5147 40 volatile volatile JJ cord-022526-j9kg00qf 5147 41 fatty fatty JJ cord-022526-j9kg00qf 5147 42 acids acid NNS cord-022526-j9kg00qf 5147 43 produced produce VBN cord-022526-j9kg00qf 5147 44 . . . cord-022526-j9kg00qf 5148 1 The the DT cord-022526-j9kg00qf 5148 2 production production NN cord-022526-j9kg00qf 5148 3 of of IN cord-022526-j9kg00qf 5148 4 large large JJ cord-022526-j9kg00qf 5148 5 amounts amount NNS cord-022526-j9kg00qf 5148 6 of of IN cord-022526-j9kg00qf 5148 7 volatile volatile JJ cord-022526-j9kg00qf 5148 8 fatty fatty JJ cord-022526-j9kg00qf 5148 9 acids acid NNS cord-022526-j9kg00qf 5148 10 stimulates stimulate VBZ cord-022526-j9kg00qf 5148 11 the the DT cord-022526-j9kg00qf 5148 12 secretion secretion NN cord-022526-j9kg00qf 5148 13 of of IN cord-022526-j9kg00qf 5148 14 large large JJ cord-022526-j9kg00qf 5148 15 volumes volume NNS cord-022526-j9kg00qf 5148 16 of of IN cord-022526-j9kg00qf 5148 17 fluid fluid NN cord-022526-j9kg00qf 5148 18 into into IN cord-022526-j9kg00qf 5148 19 the the DT cord-022526-j9kg00qf 5148 20 colon colon NN cord-022526-j9kg00qf 5148 21 . . . cord-022526-j9kg00qf 5149 1 100 100 CD cord-022526-j9kg00qf 5150 1 The the DT cord-022526-j9kg00qf 5150 2 association association NN cord-022526-j9kg00qf 5150 3 between between IN cord-022526-j9kg00qf 5150 4 feeding feeding NN cord-022526-j9kg00qf 5150 5 concentrate concentrate NN cord-022526-j9kg00qf 5150 6 and and CC cord-022526-j9kg00qf 5150 7 development development NN cord-022526-j9kg00qf 5150 8 of of IN cord-022526-j9kg00qf 5150 9 displacements displacement NNS cord-022526-j9kg00qf 5150 10 of of IN cord-022526-j9kg00qf 5150 11 the the DT cord-022526-j9kg00qf 5150 12 large large JJ cord-022526-j9kg00qf 5150 13 colon colon NN cord-022526-j9kg00qf 5150 14 is be VBZ cord-022526-j9kg00qf 5150 15 illustrated illustrate VBN cord-022526-j9kg00qf 5150 16 by by IN cord-022526-j9kg00qf 5150 17 studies study NNS cord-022526-j9kg00qf 5150 18 indicating indicate VBG cord-022526-j9kg00qf 5150 19 that that IN cord-022526-j9kg00qf 5150 20 ascending ascend VBG cord-022526-j9kg00qf 5150 21 colon colon NN cord-022526-j9kg00qf 5150 22 displacement displacement NN cord-022526-j9kg00qf 5150 23 is be VBZ cord-022526-j9kg00qf 5150 24 more more RBR cord-022526-j9kg00qf 5150 25 prevalent prevalent JJ cord-022526-j9kg00qf 5150 26 in in IN cord-022526-j9kg00qf 5150 27 horses horse NNS cord-022526-j9kg00qf 5150 28 fed feed VBD cord-022526-j9kg00qf 5150 29 a a DT cord-022526-j9kg00qf 5150 30 highconcentrate highconcentrate NN cord-022526-j9kg00qf 5150 31 , , , cord-022526-j9kg00qf 5150 32 low low JJ cord-022526-j9kg00qf 5150 33 - - HYPH cord-022526-j9kg00qf 5150 34 roughage roughage NN cord-022526-j9kg00qf 5150 35 diet diet NN cord-022526-j9kg00qf 5150 36 . . . cord-022526-j9kg00qf 5151 1 101 101 CD cord-022526-j9kg00qf 5151 2 Abnormal abnormal JJ cord-022526-j9kg00qf 5151 3 motility motility NN cord-022526-j9kg00qf 5151 4 patterns pattern NNS cord-022526-j9kg00qf 5151 5 of of IN cord-022526-j9kg00qf 5151 6 the the DT cord-022526-j9kg00qf 5151 7 ascending ascend VBG cord-022526-j9kg00qf 5151 8 colon colon NN cord-022526-j9kg00qf 5151 9 also also RB cord-022526-j9kg00qf 5151 10 have have VBP cord-022526-j9kg00qf 5151 11 been be VBN cord-022526-j9kg00qf 5151 12 suggested suggest VBN cord-022526-j9kg00qf 5151 13 to to TO cord-022526-j9kg00qf 5151 14 contribute contribute VB cord-022526-j9kg00qf 5151 15 to to IN cord-022526-j9kg00qf 5151 16 the the DT cord-022526-j9kg00qf 5151 17 development development NN cord-022526-j9kg00qf 5151 18 of of IN cord-022526-j9kg00qf 5151 19 colonic colonic JJ cord-022526-j9kg00qf 5151 20 displacement displacement NN cord-022526-j9kg00qf 5151 21 . . . cord-022526-j9kg00qf 5152 1 Feeding feeding NN cord-022526-j9kg00qf 5152 2 stimulates stimulate VBZ cord-022526-j9kg00qf 5152 3 colonic colonic JJ cord-022526-j9kg00qf 5152 4 motility motility NN cord-022526-j9kg00qf 5152 5 via via IN cord-022526-j9kg00qf 5152 6 the the DT cord-022526-j9kg00qf 5152 7 gastrocolic gastrocolic JJ cord-022526-j9kg00qf 5152 8 reflex reflex NN cord-022526-j9kg00qf 5152 9 , , , cord-022526-j9kg00qf 5152 10 but but CC cord-022526-j9kg00qf 5152 11 large large JJ cord-022526-j9kg00qf 5152 12 meals meal NNS cord-022526-j9kg00qf 5152 13 may may MD cord-022526-j9kg00qf 5152 14 alter alter VB cord-022526-j9kg00qf 5152 15 normal normal JJ cord-022526-j9kg00qf 5152 16 motility motility NN cord-022526-j9kg00qf 5152 17 patterns pattern NNS cord-022526-j9kg00qf 5152 18 and and CC cord-022526-j9kg00qf 5152 19 concurrently concurrently RB cord-022526-j9kg00qf 5152 20 allow allow VB cord-022526-j9kg00qf 5152 21 rapid rapid JJ cord-022526-j9kg00qf 5152 22 accumulation accumulation NN cord-022526-j9kg00qf 5152 23 of of IN cord-022526-j9kg00qf 5152 24 gas gas NN cord-022526-j9kg00qf 5152 25 and and CC cord-022526-j9kg00qf 5152 26 fluid fluid NN cord-022526-j9kg00qf 5152 27 from from IN cord-022526-j9kg00qf 5152 28 fermentation fermentation NN cord-022526-j9kg00qf 5152 29 . . . cord-022526-j9kg00qf 5153 1 31 31 CD cord-022526-j9kg00qf 5153 2 , , , cord-022526-j9kg00qf 5153 3 102 102 CD cord-022526-j9kg00qf 5153 4 Migration migration NN cord-022526-j9kg00qf 5153 5 of of IN cord-022526-j9kg00qf 5153 6 parasite parasite NN cord-022526-j9kg00qf 5153 7 larvae larva NNS cord-022526-j9kg00qf 5153 8 ( ( -LRB- cord-022526-j9kg00qf 5153 9 strongyles strongyles NNP cord-022526-j9kg00qf 5153 10 ) ) -RRB- cord-022526-j9kg00qf 5153 11 through through IN cord-022526-j9kg00qf 5153 12 the the DT cord-022526-j9kg00qf 5153 13 intestinal intestinal JJ cord-022526-j9kg00qf 5153 14 wall wall NN cord-022526-j9kg00qf 5153 15 also also RB cord-022526-j9kg00qf 5153 16 has have VBZ cord-022526-j9kg00qf 5153 17 been be VBN cord-022526-j9kg00qf 5153 18 shown show VBN cord-022526-j9kg00qf 5153 19 to to TO cord-022526-j9kg00qf 5153 20 alter alter VB cord-022526-j9kg00qf 5153 21 colonic colonic JJ cord-022526-j9kg00qf 5153 22 motility motility NN cord-022526-j9kg00qf 5153 23 patterns pattern NNS cord-022526-j9kg00qf 5153 24 . . . cord-022526-j9kg00qf 5154 1 Other other JJ cord-022526-j9kg00qf 5154 2 experimental experimental JJ cord-022526-j9kg00qf 5154 3 studies study NNS cord-022526-j9kg00qf 5154 4 also also RB cord-022526-j9kg00qf 5154 5 have have VBP cord-022526-j9kg00qf 5154 6 shown show VBN cord-022526-j9kg00qf 5154 7 that that IN cord-022526-j9kg00qf 5154 8 Strongylus Strongylus NNP cord-022526-j9kg00qf 5154 9 vulgaris vulgaris NN cord-022526-j9kg00qf 5154 10 infection infection NN cord-022526-j9kg00qf 5154 11 results result VBZ cord-022526-j9kg00qf 5154 12 in in IN cord-022526-j9kg00qf 5154 13 reduced reduce VBN cord-022526-j9kg00qf 5154 14 blood blood NN cord-022526-j9kg00qf 5154 15 flow flow NN cord-022526-j9kg00qf 5154 16 to to IN cord-022526-j9kg00qf 5154 17 segments segment NNS cord-022526-j9kg00qf 5154 18 of of IN cord-022526-j9kg00qf 5154 19 the the DT cord-022526-j9kg00qf 5154 20 large large JJ cord-022526-j9kg00qf 5154 21 intestine intestine NN cord-022526-j9kg00qf 5154 22 without without IN cord-022526-j9kg00qf 5154 23 necessarily necessarily RB cord-022526-j9kg00qf 5154 24 causing cause VBG cord-022526-j9kg00qf 5154 25 infarction infarction NN cord-022526-j9kg00qf 5154 26 . . . cord-022526-j9kg00qf 5155 1 Electric electric JJ cord-022526-j9kg00qf 5155 2 activity activity NN cord-022526-j9kg00qf 5155 3 of of IN cord-022526-j9kg00qf 5155 4 the the DT cord-022526-j9kg00qf 5155 5 colon colon NN cord-022526-j9kg00qf 5155 6 and and CC cord-022526-j9kg00qf 5155 7 cecocolic cecocolic JJ cord-022526-j9kg00qf 5155 8 junction junction NN cord-022526-j9kg00qf 5155 9 increases increase NNS cord-022526-j9kg00qf 5155 10 after after IN cord-022526-j9kg00qf 5155 11 infection infection NN cord-022526-j9kg00qf 5155 12 with with IN cord-022526-j9kg00qf 5155 13 S. S. NNP cord-022526-j9kg00qf 5155 14 vulgaris vulgaris NN cord-022526-j9kg00qf 5155 15 and and CC cord-022526-j9kg00qf 5155 16 cyathostome cyathostome NN cord-022526-j9kg00qf 5155 17 larvae larva NNS cord-022526-j9kg00qf 5155 18 , , , cord-022526-j9kg00qf 5155 19 probably probably RB cord-022526-j9kg00qf 5155 20 reflecting reflect VBG cord-022526-j9kg00qf 5155 21 a a DT cord-022526-j9kg00qf 5155 22 direct direct JJ cord-022526-j9kg00qf 5155 23 effect effect NN cord-022526-j9kg00qf 5155 24 of of IN cord-022526-j9kg00qf 5155 25 migration migration NN cord-022526-j9kg00qf 5155 26 through through IN cord-022526-j9kg00qf 5155 27 the the DT cord-022526-j9kg00qf 5155 28 intestine intestine NN cord-022526-j9kg00qf 5155 29 and and CC cord-022526-j9kg00qf 5155 30 an an DT cord-022526-j9kg00qf 5155 31 early early JJ cord-022526-j9kg00qf 5155 32 response response NN cord-022526-j9kg00qf 5155 33 to to IN cord-022526-j9kg00qf 5155 34 reduced reduce VBN cord-022526-j9kg00qf 5155 35 blood blood NN cord-022526-j9kg00qf 5155 36 flow flow NN cord-022526-j9kg00qf 5155 37 . . . cord-022526-j9kg00qf 5156 1 103 103 CD cord-022526-j9kg00qf 5156 2 Displacements displacement NNS cord-022526-j9kg00qf 5156 3 of of IN cord-022526-j9kg00qf 5156 4 the the DT cord-022526-j9kg00qf 5156 5 ascending ascend VBG cord-022526-j9kg00qf 5156 6 colon colon NN cord-022526-j9kg00qf 5156 7 generally generally RB cord-022526-j9kg00qf 5156 8 are be VBP cord-022526-j9kg00qf 5156 9 divided divide VBN cord-022526-j9kg00qf 5156 10 into into IN cord-022526-j9kg00qf 5156 11 three three CD cord-022526-j9kg00qf 5156 12 types type NNS cord-022526-j9kg00qf 5156 13 : : : cord-022526-j9kg00qf 5156 14 left leave VBN cord-022526-j9kg00qf 5156 15 dorsal dorsal JJ cord-022526-j9kg00qf 5156 16 displacement displacement NN cord-022526-j9kg00qf 5156 17 , , , cord-022526-j9kg00qf 5156 18 right right JJ cord-022526-j9kg00qf 5156 19 dorsal dorsal JJ cord-022526-j9kg00qf 5156 20 displacement displacement NN cord-022526-j9kg00qf 5156 21 , , , cord-022526-j9kg00qf 5156 22 and and CC cord-022526-j9kg00qf 5156 23 retroflexion retroflexion NN cord-022526-j9kg00qf 5156 24 . . . cord-022526-j9kg00qf 5157 1 Left leave VBN cord-022526-j9kg00qf 5157 2 dorsal dorsal JJ cord-022526-j9kg00qf 5157 3 displacement displacement NN cord-022526-j9kg00qf 5157 4 is be VBZ cord-022526-j9kg00qf 5157 5 characterized characterize VBN cord-022526-j9kg00qf 5157 6 by by IN cord-022526-j9kg00qf 5157 7 entrapment entrapment NN cord-022526-j9kg00qf 5157 8 of of IN cord-022526-j9kg00qf 5157 9 the the DT cord-022526-j9kg00qf 5157 10 ascending ascend VBG cord-022526-j9kg00qf 5157 11 colon colon NN cord-022526-j9kg00qf 5157 12 in in IN cord-022526-j9kg00qf 5157 13 the the DT cord-022526-j9kg00qf 5157 14 renosplenic renosplenic JJ cord-022526-j9kg00qf 5157 15 space space NN cord-022526-j9kg00qf 5157 16 . . . cord-022526-j9kg00qf 5158 1 The the DT cord-022526-j9kg00qf 5158 2 colon colon NN cord-022526-j9kg00qf 5158 3 often often RB cord-022526-j9kg00qf 5158 4 is be VBZ cord-022526-j9kg00qf 5158 5 twisted twist VBN cord-022526-j9kg00qf 5158 6 180 180 CD cord-022526-j9kg00qf 5158 7 degrees degree NNS cord-022526-j9kg00qf 5158 8 such such JJ cord-022526-j9kg00qf 5158 9 that that IN cord-022526-j9kg00qf 5158 10 the the DT cord-022526-j9kg00qf 5158 11 left left JJ cord-022526-j9kg00qf 5158 12 ventral ventral JJ cord-022526-j9kg00qf 5158 13 colon colon NN cord-022526-j9kg00qf 5158 14 is be VBZ cord-022526-j9kg00qf 5158 15 situated situate VBN cord-022526-j9kg00qf 5158 16 in in IN cord-022526-j9kg00qf 5158 17 a a DT cord-022526-j9kg00qf 5158 18 dorsal dorsal JJ cord-022526-j9kg00qf 5158 19 position position NN cord-022526-j9kg00qf 5158 20 relative relative JJ cord-022526-j9kg00qf 5158 21 to to IN cord-022526-j9kg00qf 5158 22 the the DT cord-022526-j9kg00qf 5158 23 left left JJ cord-022526-j9kg00qf 5158 24 dorsal dorsal JJ cord-022526-j9kg00qf 5158 25 colon colon NN cord-022526-j9kg00qf 5158 26 . . . cord-022526-j9kg00qf 5159 1 The the DT cord-022526-j9kg00qf 5159 2 entrapped entrap VBN cord-022526-j9kg00qf 5159 3 portion portion NN cord-022526-j9kg00qf 5159 4 may may MD cord-022526-j9kg00qf 5159 5 be be VB cord-022526-j9kg00qf 5159 6 only only RB cord-022526-j9kg00qf 5159 7 the the DT cord-022526-j9kg00qf 5159 8 pelvic pelvic JJ cord-022526-j9kg00qf 5159 9 flexure flexure NN cord-022526-j9kg00qf 5159 10 or or CC cord-022526-j9kg00qf 5159 11 may may MD cord-022526-j9kg00qf 5159 12 involve involve VB cord-022526-j9kg00qf 5159 13 a a DT cord-022526-j9kg00qf 5159 14 large large JJ cord-022526-j9kg00qf 5159 15 portion portion NN cord-022526-j9kg00qf 5159 16 of of IN cord-022526-j9kg00qf 5159 17 the the DT cord-022526-j9kg00qf 5159 18 ascending ascend VBG cord-022526-j9kg00qf 5159 19 colon colon NN cord-022526-j9kg00qf 5159 20 , , , cord-022526-j9kg00qf 5159 21 with with IN cord-022526-j9kg00qf 5159 22 the the DT cord-022526-j9kg00qf 5159 23 pelvic pelvic JJ cord-022526-j9kg00qf 5159 24 flexure flexure NN cord-022526-j9kg00qf 5159 25 situated situate VBN cord-022526-j9kg00qf 5159 26 near near IN cord-022526-j9kg00qf 5159 27 the the DT cord-022526-j9kg00qf 5159 28 diaphragm diaphragm NN cord-022526-j9kg00qf 5159 29 . . . cord-022526-j9kg00qf 5160 1 The the DT cord-022526-j9kg00qf 5160 2 colon colon NN cord-022526-j9kg00qf 5160 3 may may MD cord-022526-j9kg00qf 5160 4 become become VB cord-022526-j9kg00qf 5160 5 entrapped entrap VBN cord-022526-j9kg00qf 5160 6 by by IN cord-022526-j9kg00qf 5160 7 migrating migrate VBG cord-022526-j9kg00qf 5160 8 dorsally dorsally RB cord-022526-j9kg00qf 5160 9 between between IN cord-022526-j9kg00qf 5160 10 the the DT cord-022526-j9kg00qf 5160 11 left left JJ cord-022526-j9kg00qf 5160 12 abdominal abdominal JJ cord-022526-j9kg00qf 5160 13 wall wall NN cord-022526-j9kg00qf 5160 14 and and CC cord-022526-j9kg00qf 5160 15 the the DT cord-022526-j9kg00qf 5160 16 spleen spleen NN cord-022526-j9kg00qf 5160 17 or or CC cord-022526-j9kg00qf 5160 18 may may MD cord-022526-j9kg00qf 5160 19 migrate migrate VB cord-022526-j9kg00qf 5160 20 in in IN cord-022526-j9kg00qf 5160 21 a a DT cord-022526-j9kg00qf 5160 22 caudodorsal caudodorsal NN cord-022526-j9kg00qf 5160 23 direction direction NN cord-022526-j9kg00qf 5160 24 over over IN cord-022526-j9kg00qf 5160 25 the the DT cord-022526-j9kg00qf 5160 26 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5160 27 ligament ligament NN cord-022526-j9kg00qf 5160 28 . . . cord-022526-j9kg00qf 5161 1 Occasionally occasionally RB cord-022526-j9kg00qf 5161 2 , , , cord-022526-j9kg00qf 5161 3 one one PRP cord-022526-j9kg00qf 5161 4 can can MD cord-022526-j9kg00qf 5161 5 palpate palpate VB cord-022526-j9kg00qf 5161 6 the the DT cord-022526-j9kg00qf 5161 7 ascending ascend VBG cord-022526-j9kg00qf 5161 8 colon colon NN cord-022526-j9kg00qf 5161 9 between between IN cord-022526-j9kg00qf 5161 10 the the DT cord-022526-j9kg00qf 5161 11 spleen spleen NNS cord-022526-j9kg00qf 5161 12 and and CC cord-022526-j9kg00qf 5161 13 abdominal abdominal JJ cord-022526-j9kg00qf 5161 14 wall wall NN cord-022526-j9kg00qf 5161 15 , , , cord-022526-j9kg00qf 5161 16 lending lend VBG cord-022526-j9kg00qf 5161 17 support support NN cord-022526-j9kg00qf 5161 18 to to IN cord-022526-j9kg00qf 5161 19 the the DT cord-022526-j9kg00qf 5161 20 first first JJ cord-022526-j9kg00qf 5161 21 mechanism mechanism NN cord-022526-j9kg00qf 5161 22 of of IN cord-022526-j9kg00qf 5161 23 displacement displacement NN cord-022526-j9kg00qf 5161 24 . . . cord-022526-j9kg00qf 5162 1 Gastric gastric JJ cord-022526-j9kg00qf 5162 2 distention distention NN cord-022526-j9kg00qf 5162 3 is be VBZ cord-022526-j9kg00qf 5162 4 thought think VBN cord-022526-j9kg00qf 5162 5 to to TO cord-022526-j9kg00qf 5162 6 predispose predispose VB cord-022526-j9kg00qf 5162 7 horses horse NNS cord-022526-j9kg00qf 5162 8 to to IN cord-022526-j9kg00qf 5162 9 left leave VBN cord-022526-j9kg00qf 5162 10 dorsal dorsal JJ cord-022526-j9kg00qf 5162 11 displacement displacement NN cord-022526-j9kg00qf 5162 12 of of IN cord-022526-j9kg00qf 5162 13 the the DT cord-022526-j9kg00qf 5162 14 ascending ascend VBG cord-022526-j9kg00qf 5162 15 colon colon NN cord-022526-j9kg00qf 5162 16 by by IN cord-022526-j9kg00qf 5162 17 displacing displace VBG cord-022526-j9kg00qf 5162 18 the the DT cord-022526-j9kg00qf 5162 19 spleen spleen NNS cord-022526-j9kg00qf 5162 20 medially medially RB cord-022526-j9kg00qf 5162 21 , , , cord-022526-j9kg00qf 5162 22 allowing allow VBG cord-022526-j9kg00qf 5162 23 the the DT cord-022526-j9kg00qf 5162 24 colon colon NN cord-022526-j9kg00qf 5162 25 room room NN cord-022526-j9kg00qf 5162 26 to to TO cord-022526-j9kg00qf 5162 27 migrate migrate VB cord-022526-j9kg00qf 5162 28 along along IN cord-022526-j9kg00qf 5162 29 the the DT cord-022526-j9kg00qf 5162 30 abdominal abdominal JJ cord-022526-j9kg00qf 5162 31 wall wall NN cord-022526-j9kg00qf 5162 32 . . . cord-022526-j9kg00qf 5163 1 Right right JJ cord-022526-j9kg00qf 5163 2 dorsal dorsal JJ cord-022526-j9kg00qf 5163 3 displacement displacement NN cord-022526-j9kg00qf 5163 4 begins begin VBZ cord-022526-j9kg00qf 5163 5 by by IN cord-022526-j9kg00qf 5163 6 movement movement NN cord-022526-j9kg00qf 5163 7 of of IN cord-022526-j9kg00qf 5163 8 the the DT cord-022526-j9kg00qf 5163 9 colon colon NN cord-022526-j9kg00qf 5163 10 cranially cranially NN cord-022526-j9kg00qf 5163 11 , , , cord-022526-j9kg00qf 5163 12 medial medial JJ cord-022526-j9kg00qf 5163 13 ( ( -LRB- cord-022526-j9kg00qf 5163 14 medial medial JJ cord-022526-j9kg00qf 5163 15 flexion flexion NN cord-022526-j9kg00qf 5163 16 ) ) -RRB- cord-022526-j9kg00qf 5163 17 or or CC cord-022526-j9kg00qf 5163 18 lateral lateral JJ cord-022526-j9kg00qf 5163 19 ( ( -LRB- cord-022526-j9kg00qf 5163 20 lateral lateral JJ cord-022526-j9kg00qf 5163 21 flexion flexion NN cord-022526-j9kg00qf 5163 22 ) ) -RRB- cord-022526-j9kg00qf 5163 23 to to IN cord-022526-j9kg00qf 5163 24 the the DT cord-022526-j9kg00qf 5163 25 cecum cecum NN cord-022526-j9kg00qf 5163 26 . . . cord-022526-j9kg00qf 5164 1 According accord VBG cord-022526-j9kg00qf 5164 2 to to IN cord-022526-j9kg00qf 5164 3 one one CD cord-022526-j9kg00qf 5164 4 author author NN cord-022526-j9kg00qf 5164 5 , , , cord-022526-j9kg00qf 5164 6 the the DT cord-022526-j9kg00qf 5164 7 proportion proportion NN cord-022526-j9kg00qf 5164 8 of of IN cord-022526-j9kg00qf 5164 9 right right JJ cord-022526-j9kg00qf 5164 10 dorsal dorsal JJ cord-022526-j9kg00qf 5164 11 displacements displacement NNS cord-022526-j9kg00qf 5164 12 with with IN cord-022526-j9kg00qf 5164 13 medial medial JJ cord-022526-j9kg00qf 5164 14 versus versus IN cord-022526-j9kg00qf 5164 15 lateral lateral JJ cord-022526-j9kg00qf 5164 16 flexion flexion NN cord-022526-j9kg00qf 5164 17 is be VBZ cord-022526-j9kg00qf 5164 18 approximately approximately RB cord-022526-j9kg00qf 5164 19 1:15 1:15 CD cord-022526-j9kg00qf 5164 20 . . . cord-022526-j9kg00qf 5164 21 104 104 CD cord-022526-j9kg00qf 5165 1 In in IN cord-022526-j9kg00qf 5165 2 either either DT cord-022526-j9kg00qf 5165 3 case case NN cord-022526-j9kg00qf 5165 4 the the DT cord-022526-j9kg00qf 5165 5 pelvic pelvic JJ cord-022526-j9kg00qf 5165 6 flexure flexure NN cord-022526-j9kg00qf 5165 7 ends end VBZ cord-022526-j9kg00qf 5165 8 up up RP cord-022526-j9kg00qf 5165 9 adjacent adjacent JJ cord-022526-j9kg00qf 5165 10 to to IN cord-022526-j9kg00qf 5165 11 the the DT cord-022526-j9kg00qf 5165 12 diaphragm diaphragm NN cord-022526-j9kg00qf 5165 13 . . . cord-022526-j9kg00qf 5166 1 Retroflexion Retroflexion NNP cord-022526-j9kg00qf 5166 2 of of IN cord-022526-j9kg00qf 5166 3 the the DT cord-022526-j9kg00qf 5166 4 ascending ascend VBG cord-022526-j9kg00qf 5166 5 colon colon NN cord-022526-j9kg00qf 5166 6 occurs occur VBZ cord-022526-j9kg00qf 5166 7 by by IN cord-022526-j9kg00qf 5166 8 movement movement NN cord-022526-j9kg00qf 5166 9 of of IN cord-022526-j9kg00qf 5166 10 the the DT cord-022526-j9kg00qf 5166 11 pelvic pelvic JJ cord-022526-j9kg00qf 5166 12 flexure flexure NN cord-022526-j9kg00qf 5166 13 cranially cranially RB cord-022526-j9kg00qf 5166 14 without without IN cord-022526-j9kg00qf 5166 15 movement movement NN cord-022526-j9kg00qf 5166 16 of of IN cord-022526-j9kg00qf 5166 17 the the DT cord-022526-j9kg00qf 5166 18 sternal sternal JJ cord-022526-j9kg00qf 5166 19 or or CC cord-022526-j9kg00qf 5166 20 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5166 21 flexures flexure NNS cord-022526-j9kg00qf 5166 22 . . . cord-022526-j9kg00qf 5167 1 Displacement displacement NN cord-022526-j9kg00qf 5167 2 of of IN cord-022526-j9kg00qf 5167 3 the the DT cord-022526-j9kg00qf 5167 4 ascending ascend VBG cord-022526-j9kg00qf 5167 5 colon colon NN cord-022526-j9kg00qf 5167 6 partially partially RB cord-022526-j9kg00qf 5167 7 obstructs obstruct VBZ cord-022526-j9kg00qf 5167 8 the the DT cord-022526-j9kg00qf 5167 9 lumen lumen NN cord-022526-j9kg00qf 5167 10 , , , cord-022526-j9kg00qf 5167 11 resulting result VBG cord-022526-j9kg00qf 5167 12 in in IN cord-022526-j9kg00qf 5167 13 accumulation accumulation NN cord-022526-j9kg00qf 5167 14 of of IN cord-022526-j9kg00qf 5167 15 gas gas NN cord-022526-j9kg00qf 5167 16 or or CC cord-022526-j9kg00qf 5167 17 ingesta ingesta NNS cord-022526-j9kg00qf 5167 18 and and CC cord-022526-j9kg00qf 5167 19 causing cause VBG cord-022526-j9kg00qf 5167 20 distention distention NN cord-022526-j9kg00qf 5167 21 . . . cord-022526-j9kg00qf 5168 1 Secretion secretion NN cord-022526-j9kg00qf 5168 2 of of IN cord-022526-j9kg00qf 5168 3 fluid fluid NN cord-022526-j9kg00qf 5168 4 in in IN cord-022526-j9kg00qf 5168 5 response response NN cord-022526-j9kg00qf 5168 6 may may MD cord-022526-j9kg00qf 5168 7 exacerbate exacerbate VB cord-022526-j9kg00qf 5168 8 the the DT cord-022526-j9kg00qf 5168 9 distention distention NN cord-022526-j9kg00qf 5168 10 . . . cord-022526-j9kg00qf 5169 1 105 105 CD cord-022526-j9kg00qf 5169 2 Tension tension NN cord-022526-j9kg00qf 5169 3 and and CC cord-022526-j9kg00qf 5169 4 stretch stretch NN cord-022526-j9kg00qf 5169 5 of of IN cord-022526-j9kg00qf 5169 6 the the DT cord-022526-j9kg00qf 5169 7 visceral visceral JJ cord-022526-j9kg00qf 5169 8 wall wall NN cord-022526-j9kg00qf 5169 9 is be VBZ cord-022526-j9kg00qf 5169 10 an an DT cord-022526-j9kg00qf 5169 11 important important JJ cord-022526-j9kg00qf 5169 12 source source NN cord-022526-j9kg00qf 5169 13 of of IN cord-022526-j9kg00qf 5169 14 the the DT cord-022526-j9kg00qf 5169 15 pain pain NN cord-022526-j9kg00qf 5169 16 associated associate VBN cord-022526-j9kg00qf 5169 17 with with IN cord-022526-j9kg00qf 5169 18 colonic colonic JJ cord-022526-j9kg00qf 5169 19 displacement displacement NN cord-022526-j9kg00qf 5169 20 . . . cord-022526-j9kg00qf 5170 1 Tension tension NN cord-022526-j9kg00qf 5170 2 on on IN cord-022526-j9kg00qf 5170 3 mesenteric mesenteric JJ cord-022526-j9kg00qf 5170 4 attachments attachment NNS cord-022526-j9kg00qf 5170 5 and and CC cord-022526-j9kg00qf 5170 6 the the DT cord-022526-j9kg00qf 5170 7 root root NN cord-022526-j9kg00qf 5170 8 of of IN cord-022526-j9kg00qf 5170 9 the the DT cord-022526-j9kg00qf 5170 10 mesentery mesentery NN cord-022526-j9kg00qf 5170 11 by by IN cord-022526-j9kg00qf 5170 12 the the DT cord-022526-j9kg00qf 5170 13 enlarged enlarged JJ cord-022526-j9kg00qf 5170 14 colon colon NN cord-022526-j9kg00qf 5170 15 also also RB cord-022526-j9kg00qf 5170 16 may may MD cord-022526-j9kg00qf 5170 17 cause cause VB cord-022526-j9kg00qf 5170 18 pain pain NN cord-022526-j9kg00qf 5170 19 . . . cord-022526-j9kg00qf 5171 1 99 99 CD cord-022526-j9kg00qf 5171 2 Ischemia ischemia NN cord-022526-j9kg00qf 5171 3 rarely rarely RB cord-022526-j9kg00qf 5171 4 is be VBZ cord-022526-j9kg00qf 5171 5 associated associate VBN cord-022526-j9kg00qf 5171 6 with with IN cord-022526-j9kg00qf 5171 7 nonstrangulating nonstrangulate VBG cord-022526-j9kg00qf 5171 8 displacement displacement NN cord-022526-j9kg00qf 5171 9 of of IN cord-022526-j9kg00qf 5171 10 the the DT cord-022526-j9kg00qf 5171 11 colon colon NN cord-022526-j9kg00qf 5171 12 . . . cord-022526-j9kg00qf 5172 1 However however RB cord-022526-j9kg00qf 5172 2 , , , cord-022526-j9kg00qf 5172 3 vascular vascular JJ cord-022526-j9kg00qf 5172 4 congestion congestion NN cord-022526-j9kg00qf 5172 5 and and CC cord-022526-j9kg00qf 5172 6 edema edema NN cord-022526-j9kg00qf 5172 7 often often RB cord-022526-j9kg00qf 5172 8 occur occur VBP cord-022526-j9kg00qf 5172 9 in in IN cord-022526-j9kg00qf 5172 10 the the DT cord-022526-j9kg00qf 5172 11 displaced displace VBN cord-022526-j9kg00qf 5172 12 segments segment NNS cord-022526-j9kg00qf 5172 13 of of IN cord-022526-j9kg00qf 5172 14 colon colon NN cord-022526-j9kg00qf 5172 15 , , , cord-022526-j9kg00qf 5172 16 resulting result VBG cord-022526-j9kg00qf 5172 17 from from IN cord-022526-j9kg00qf 5172 18 increased increase VBN cord-022526-j9kg00qf 5172 19 hydrostatic hydrostatic JJ cord-022526-j9kg00qf 5172 20 pressure pressure NN cord-022526-j9kg00qf 5172 21 from from IN cord-022526-j9kg00qf 5172 22 reduced reduce VBN cord-022526-j9kg00qf 5172 23 venous venous JJ cord-022526-j9kg00qf 5172 24 outflow outflow NN cord-022526-j9kg00qf 5172 25 . . . cord-022526-j9kg00qf 5173 1 Morphologic morphologic JJ cord-022526-j9kg00qf 5173 2 damage damage NN cord-022526-j9kg00qf 5173 3 to to IN cord-022526-j9kg00qf 5173 4 the the DT cord-022526-j9kg00qf 5173 5 tissues tissue NNS cord-022526-j9kg00qf 5173 6 is be VBZ cord-022526-j9kg00qf 5173 7 usually usually RB cord-022526-j9kg00qf 5173 8 minor minor JJ cord-022526-j9kg00qf 5173 9 . . . cord-022526-j9kg00qf 5174 1 Clinically clinically RB cord-022526-j9kg00qf 5174 2 , , , cord-022526-j9kg00qf 5174 3 displacement displacement NN cord-022526-j9kg00qf 5174 4 of of IN cord-022526-j9kg00qf 5174 5 the the DT cord-022526-j9kg00qf 5174 6 ascending ascend VBG cord-022526-j9kg00qf 5174 7 colon colon NN cord-022526-j9kg00qf 5174 8 is be VBZ cord-022526-j9kg00qf 5174 9 characterized characterize VBN cord-022526-j9kg00qf 5174 10 by by IN cord-022526-j9kg00qf 5174 11 intermittent intermittent JJ cord-022526-j9kg00qf 5174 12 signs sign NNS cord-022526-j9kg00qf 5174 13 of of IN cord-022526-j9kg00qf 5174 14 mild mild JJ cord-022526-j9kg00qf 5174 15 to to TO cord-022526-j9kg00qf 5174 16 moderate moderate JJ cord-022526-j9kg00qf 5174 17 abdominal abdominal JJ cord-022526-j9kg00qf 5174 18 pain pain NN cord-022526-j9kg00qf 5174 19 of of IN cord-022526-j9kg00qf 5174 20 acute acute JJ cord-022526-j9kg00qf 5174 21 onset onset NN cord-022526-j9kg00qf 5174 22 . . . cord-022526-j9kg00qf 5175 1 However however RB cord-022526-j9kg00qf 5175 2 , , , cord-022526-j9kg00qf 5175 3 one one CD cord-022526-j9kg00qf 5175 4 also also RB cord-022526-j9kg00qf 5175 5 may may MD cord-022526-j9kg00qf 5175 6 note note VB cord-022526-j9kg00qf 5175 7 an an DT cord-022526-j9kg00qf 5175 8 insidious insidious JJ cord-022526-j9kg00qf 5175 9 onset onset NN cord-022526-j9kg00qf 5175 10 of of IN cord-022526-j9kg00qf 5175 11 colic colic NN cord-022526-j9kg00qf 5175 12 . . . cord-022526-j9kg00qf 5176 1 104 104 CD cord-022526-j9kg00qf 5177 1 One one CD cord-022526-j9kg00qf 5177 2 may may MD cord-022526-j9kg00qf 5177 3 note note VB cord-022526-j9kg00qf 5177 4 dehydration dehydration NN cord-022526-j9kg00qf 5177 5 if if IN cord-022526-j9kg00qf 5177 6 the the DT cord-022526-j9kg00qf 5177 7 duration duration NN cord-022526-j9kg00qf 5177 8 of of IN cord-022526-j9kg00qf 5177 9 the the DT cord-022526-j9kg00qf 5177 10 displacement displacement NN cord-022526-j9kg00qf 5177 11 is be VBZ cord-022526-j9kg00qf 5177 12 prolonged prolong VBN cord-022526-j9kg00qf 5177 13 . . . cord-022526-j9kg00qf 5178 1 The the DT cord-022526-j9kg00qf 5178 2 heart heart NN cord-022526-j9kg00qf 5178 3 rate rate NN cord-022526-j9kg00qf 5178 4 may may MD cord-022526-j9kg00qf 5178 5 be be VB cord-022526-j9kg00qf 5178 6 elevated elevate VBN cord-022526-j9kg00qf 5178 7 during during IN cord-022526-j9kg00qf 5178 8 periods period NNS cord-022526-j9kg00qf 5178 9 of of IN cord-022526-j9kg00qf 5178 10 abdominal abdominal JJ cord-022526-j9kg00qf 5178 11 pain pain NN cord-022526-j9kg00qf 5178 12 but but CC cord-022526-j9kg00qf 5178 13 is be VBZ cord-022526-j9kg00qf 5178 14 often often RB cord-022526-j9kg00qf 5178 15 normal normal JJ cord-022526-j9kg00qf 5178 16 . . . cord-022526-j9kg00qf 5179 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5179 2 distention distention NN cord-022526-j9kg00qf 5179 3 may may MD cord-022526-j9kg00qf 5179 4 be be VB cord-022526-j9kg00qf 5179 5 present present JJ cord-022526-j9kg00qf 5179 6 if if IN cord-022526-j9kg00qf 5179 7 the the DT cord-022526-j9kg00qf 5179 8 colon colon NN cord-022526-j9kg00qf 5179 9 is be VBZ cord-022526-j9kg00qf 5179 10 enlarged enlarge VBN cord-022526-j9kg00qf 5179 11 by by IN cord-022526-j9kg00qf 5179 12 gas gas NN cord-022526-j9kg00qf 5179 13 , , , cord-022526-j9kg00qf 5179 14 fluid fluid NN cord-022526-j9kg00qf 5179 15 , , , cord-022526-j9kg00qf 5179 16 or or CC cord-022526-j9kg00qf 5179 17 ingesta ingesta JJ cord-022526-j9kg00qf 5179 18 . . . cord-022526-j9kg00qf 5180 1 Fecal fecal JJ cord-022526-j9kg00qf 5180 2 production production NN cord-022526-j9kg00qf 5180 3 is be VBZ cord-022526-j9kg00qf 5180 4 reduced reduce VBN cord-022526-j9kg00qf 5180 5 because because IN cord-022526-j9kg00qf 5180 6 progressive progressive JJ cord-022526-j9kg00qf 5180 7 motility motility NN cord-022526-j9kg00qf 5180 8 of of IN cord-022526-j9kg00qf 5180 9 the the DT cord-022526-j9kg00qf 5180 10 large large JJ cord-022526-j9kg00qf 5180 11 intestine intestine NN cord-022526-j9kg00qf 5180 12 is be VBZ cord-022526-j9kg00qf 5180 13 absent absent JJ cord-022526-j9kg00qf 5180 14 . . . cord-022526-j9kg00qf 5181 1 One one CD cord-022526-j9kg00qf 5181 2 often often RB cord-022526-j9kg00qf 5181 3 diagnoses diagnose VBZ cord-022526-j9kg00qf 5181 4 left leave VBN cord-022526-j9kg00qf 5181 5 dorsal dorsal JJ cord-022526-j9kg00qf 5181 6 displacements displacement NNS cord-022526-j9kg00qf 5181 7 by by IN cord-022526-j9kg00qf 5181 8 palpation palpation NN cord-022526-j9kg00qf 5181 9 per per IN cord-022526-j9kg00qf 5181 10 rectum rectum NN cord-022526-j9kg00qf 5181 11 . . . cord-022526-j9kg00qf 5182 1 One one PRP cord-022526-j9kg00qf 5182 2 can can MD cord-022526-j9kg00qf 5182 3 feel feel VB cord-022526-j9kg00qf 5182 4 the the DT cord-022526-j9kg00qf 5182 5 left left JJ cord-022526-j9kg00qf 5182 6 ventral ventral JJ cord-022526-j9kg00qf 5182 7 colon colon NN cord-022526-j9kg00qf 5182 8 in in IN cord-022526-j9kg00qf 5182 9 a a DT cord-022526-j9kg00qf 5182 10 dorsal dorsal JJ cord-022526-j9kg00qf 5182 11 position position NN cord-022526-j9kg00qf 5182 12 ; ; : cord-022526-j9kg00qf 5182 13 it -PRON- PRP cord-022526-j9kg00qf 5182 14 often often RB cord-022526-j9kg00qf 5182 15 is be VBZ cord-022526-j9kg00qf 5182 16 filled fill VBN cord-022526-j9kg00qf 5182 17 with with IN cord-022526-j9kg00qf 5182 18 gas gas NN cord-022526-j9kg00qf 5182 19 . . . cord-022526-j9kg00qf 5183 1 One one PRP cord-022526-j9kg00qf 5183 2 can can MD cord-022526-j9kg00qf 5183 3 trace trace VB cord-022526-j9kg00qf 5183 4 the the DT cord-022526-j9kg00qf 5183 5 ascending ascend VBG cord-022526-j9kg00qf 5183 6 colon colon NN cord-022526-j9kg00qf 5183 7 to to IN cord-022526-j9kg00qf 5183 8 the the DT cord-022526-j9kg00qf 5183 9 nephrosplenic nephrosplenic NNP cord-022526-j9kg00qf 5183 10 space space NN cord-022526-j9kg00qf 5183 11 , , , cord-022526-j9kg00qf 5183 12 and and CC cord-022526-j9kg00qf 5183 13 the the DT cord-022526-j9kg00qf 5183 14 spleen spleen NN cord-022526-j9kg00qf 5183 15 may may MD cord-022526-j9kg00qf 5183 16 be be VB cord-022526-j9kg00qf 5183 17 displaced displace VBN cord-022526-j9kg00qf 5183 18 medially medially RB cord-022526-j9kg00qf 5183 19 . . . cord-022526-j9kg00qf 5184 1 Alternatively alternatively RB cord-022526-j9kg00qf 5184 2 , , , cord-022526-j9kg00qf 5184 3 one one PRP cord-022526-j9kg00qf 5184 4 can can MD cord-022526-j9kg00qf 5184 5 reach reach VB cord-022526-j9kg00qf 5184 6 a a DT cord-022526-j9kg00qf 5184 7 tentative tentative JJ cord-022526-j9kg00qf 5184 8 diagnosis diagnosis NN cord-022526-j9kg00qf 5184 9 using use VBG cord-022526-j9kg00qf 5184 10 abdominal abdominal JJ cord-022526-j9kg00qf 5184 11 ultrasonography ultrasonography NN cord-022526-j9kg00qf 5184 12 . . . cord-022526-j9kg00qf 5185 1 The the DT cord-022526-j9kg00qf 5185 2 spleen spleen NN cord-022526-j9kg00qf 5185 3 is be VBZ cord-022526-j9kg00qf 5185 4 visible visible JJ cord-022526-j9kg00qf 5185 5 on on IN cord-022526-j9kg00qf 5185 6 the the DT cord-022526-j9kg00qf 5185 7 left left JJ cord-022526-j9kg00qf 5185 8 side side NN cord-022526-j9kg00qf 5185 9 of of IN cord-022526-j9kg00qf 5185 10 the the DT cord-022526-j9kg00qf 5185 11 abdomen abdomen NN cord-022526-j9kg00qf 5185 12 , , , cord-022526-j9kg00qf 5185 13 but but CC cord-022526-j9kg00qf 5185 14 the the DT cord-022526-j9kg00qf 5185 15 gasdistended gasdistended JJ cord-022526-j9kg00qf 5185 16 bowel bowel NN cord-022526-j9kg00qf 5185 17 obscures obscure VBZ cord-022526-j9kg00qf 5185 18 the the DT cord-022526-j9kg00qf 5185 19 left left JJ cord-022526-j9kg00qf 5185 20 kidney kidney NN cord-022526-j9kg00qf 5185 21 . . . cord-022526-j9kg00qf 5186 1 Evaluation evaluation NN cord-022526-j9kg00qf 5186 2 of of IN cord-022526-j9kg00qf 5186 3 this this DT cord-022526-j9kg00qf 5186 4 technique technique NN cord-022526-j9kg00qf 5186 5 indicates indicate VBZ cord-022526-j9kg00qf 5186 6 that that IN cord-022526-j9kg00qf 5186 7 false false JJ cord-022526-j9kg00qf 5186 8 positives positive NNS cord-022526-j9kg00qf 5186 9 occur occur VBP cord-022526-j9kg00qf 5186 10 in in IN cord-022526-j9kg00qf 5186 11 few few JJ cord-022526-j9kg00qf 5186 12 instances instance NNS cord-022526-j9kg00qf 5186 13 , , , cord-022526-j9kg00qf 5186 14 although although IN cord-022526-j9kg00qf 5186 15 false false JJ cord-022526-j9kg00qf 5186 16 negatives negative NNS cord-022526-j9kg00qf 5186 17 occasionally occasionally RB cord-022526-j9kg00qf 5186 18 may may MD cord-022526-j9kg00qf 5186 19 occur occur VB cord-022526-j9kg00qf 5186 20 . . . cord-022526-j9kg00qf 5187 1 106 106 CD cord-022526-j9kg00qf 5187 2 A a DT cord-022526-j9kg00qf 5187 3 definitive definitive JJ cord-022526-j9kg00qf 5187 4 diagnosis diagnosis NN cord-022526-j9kg00qf 5187 5 therefore therefore RB cord-022526-j9kg00qf 5187 6 may may MD cord-022526-j9kg00qf 5187 7 require require VB cord-022526-j9kg00qf 5187 8 surgery surgery NN cord-022526-j9kg00qf 5187 9 . . . cord-022526-j9kg00qf 5188 1 Right right JJ cord-022526-j9kg00qf 5188 2 dorsal dorsal JJ cord-022526-j9kg00qf 5188 3 displacements displacement NNS cord-022526-j9kg00qf 5188 4 are be VBP cord-022526-j9kg00qf 5188 5 characterized characterize VBN cord-022526-j9kg00qf 5188 6 by by IN cord-022526-j9kg00qf 5188 7 the the DT cord-022526-j9kg00qf 5188 8 presence presence NN cord-022526-j9kg00qf 5188 9 of of IN cord-022526-j9kg00qf 5188 10 the the DT cord-022526-j9kg00qf 5188 11 distended distended JJ cord-022526-j9kg00qf 5188 12 ventral ventral JJ cord-022526-j9kg00qf 5188 13 colon colon NN cord-022526-j9kg00qf 5188 14 running run VBG cord-022526-j9kg00qf 5188 15 across across IN cord-022526-j9kg00qf 5188 16 the the DT cord-022526-j9kg00qf 5188 17 pelvic pelvic JJ cord-022526-j9kg00qf 5188 18 inlet inlet NN cord-022526-j9kg00qf 5188 19 and and CC cord-022526-j9kg00qf 5188 20 may may MD cord-022526-j9kg00qf 5188 21 be be VB cord-022526-j9kg00qf 5188 22 felt feel VBN cord-022526-j9kg00qf 5188 23 between between IN cord-022526-j9kg00qf 5188 24 the the DT cord-022526-j9kg00qf 5188 25 cecum cecum NN cord-022526-j9kg00qf 5188 26 and and CC cord-022526-j9kg00qf 5188 27 the the DT cord-022526-j9kg00qf 5188 28 body body NN cord-022526-j9kg00qf 5188 29 wall wall NN cord-022526-j9kg00qf 5188 30 if if IN cord-022526-j9kg00qf 5188 31 a a DT cord-022526-j9kg00qf 5188 32 lateral lateral JJ cord-022526-j9kg00qf 5188 33 flexion flexion NN cord-022526-j9kg00qf 5188 34 is be VBZ cord-022526-j9kg00qf 5188 35 present present JJ cord-022526-j9kg00qf 5188 36 . . . cord-022526-j9kg00qf 5189 1 The the DT cord-022526-j9kg00qf 5189 2 pelvic pelvic JJ cord-022526-j9kg00qf 5189 3 flexure flexure NN cord-022526-j9kg00qf 5189 4 is be VBZ cord-022526-j9kg00qf 5189 5 usually usually RB cord-022526-j9kg00qf 5189 6 not not RB cord-022526-j9kg00qf 5189 7 palpable palpable JJ cord-022526-j9kg00qf 5189 8 . . . cord-022526-j9kg00qf 5190 1 Retroflexion Retroflexion NNP cord-022526-j9kg00qf 5190 2 of of IN cord-022526-j9kg00qf 5190 3 the the DT cord-022526-j9kg00qf 5190 4 ascending ascend VBG cord-022526-j9kg00qf 5190 5 colon colon NN cord-022526-j9kg00qf 5190 6 may may MD cord-022526-j9kg00qf 5190 7 produce produce VB cord-022526-j9kg00qf 5190 8 a a DT cord-022526-j9kg00qf 5190 9 palpable palpable JJ cord-022526-j9kg00qf 5190 10 kink kink NN cord-022526-j9kg00qf 5190 11 in in IN cord-022526-j9kg00qf 5190 12 the the DT cord-022526-j9kg00qf 5190 13 colon colon NN cord-022526-j9kg00qf 5190 14 . . . cord-022526-j9kg00qf 5191 1 If if IN cord-022526-j9kg00qf 5191 2 the the DT cord-022526-j9kg00qf 5191 3 displaced displace VBN cord-022526-j9kg00qf 5191 4 colons colon NNS cord-022526-j9kg00qf 5191 5 are be VBP cord-022526-j9kg00qf 5191 6 not not RB cord-022526-j9kg00qf 5191 7 distended distend VBN cord-022526-j9kg00qf 5191 8 by by IN cord-022526-j9kg00qf 5191 9 gas gas NN cord-022526-j9kg00qf 5191 10 in in IN cord-022526-j9kg00qf 5191 11 the the DT cord-022526-j9kg00qf 5191 12 instance instance NN cord-022526-j9kg00qf 5191 13 of of IN cord-022526-j9kg00qf 5191 14 right right JJ cord-022526-j9kg00qf 5191 15 dorsal dorsal JJ cord-022526-j9kg00qf 5191 16 displacement displacement NN cord-022526-j9kg00qf 5191 17 and and CC cord-022526-j9kg00qf 5191 18 retroflexion retroflexion NN cord-022526-j9kg00qf 5191 19 , , , cord-022526-j9kg00qf 5191 20 the the DT cord-022526-j9kg00qf 5191 21 ascending ascend VBG cord-022526-j9kg00qf 5191 22 colon colon NN cord-022526-j9kg00qf 5191 23 may may MD cord-022526-j9kg00qf 5191 24 not not RB cord-022526-j9kg00qf 5191 25 be be VB cord-022526-j9kg00qf 5191 26 palpable palpable JJ cord-022526-j9kg00qf 5191 27 and and CC cord-022526-j9kg00qf 5191 28 is be VBZ cord-022526-j9kg00qf 5191 29 conspicuous conspicuous JJ cord-022526-j9kg00qf 5191 30 by by IN cord-022526-j9kg00qf 5191 31 its -PRON- PRP$ cord-022526-j9kg00qf 5191 32 absence absence NN cord-022526-j9kg00qf 5191 33 from from IN cord-022526-j9kg00qf 5191 34 a a DT cord-022526-j9kg00qf 5191 35 normal normal JJ cord-022526-j9kg00qf 5191 36 position position NN cord-022526-j9kg00qf 5191 37 . . . cord-022526-j9kg00qf 5192 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5192 2 fluid fluid NN cord-022526-j9kg00qf 5192 3 may may MD cord-022526-j9kg00qf 5192 4 increase increase VB cord-022526-j9kg00qf 5192 5 in in IN cord-022526-j9kg00qf 5192 6 amount amount NN cord-022526-j9kg00qf 5192 7 , , , cord-022526-j9kg00qf 5192 8 but but CC cord-022526-j9kg00qf 5192 9 the the DT cord-022526-j9kg00qf 5192 10 color color NN cord-022526-j9kg00qf 5192 11 , , , cord-022526-j9kg00qf 5192 12 protein protein NN cord-022526-j9kg00qf 5192 13 concentration concentration NN cord-022526-j9kg00qf 5192 14 , , , cord-022526-j9kg00qf 5192 15 and and CC cord-022526-j9kg00qf 5192 16 white white JJ cord-022526-j9kg00qf 5192 17 blood blood NN cord-022526-j9kg00qf 5192 18 cell cell NN cord-022526-j9kg00qf 5192 19 count count NN cord-022526-j9kg00qf 5192 20 are be VBP cord-022526-j9kg00qf 5192 21 usually usually RB cord-022526-j9kg00qf 5192 22 normal normal JJ cord-022526-j9kg00qf 5192 23 . . . cord-022526-j9kg00qf 5193 1 However however RB cord-022526-j9kg00qf 5193 2 , , , cord-022526-j9kg00qf 5193 3 as as IN cord-022526-j9kg00qf 5193 4 the the DT cord-022526-j9kg00qf 5193 5 displaced displace VBN cord-022526-j9kg00qf 5193 6 segment segment NN cord-022526-j9kg00qf 5193 7 becomes become VBZ cord-022526-j9kg00qf 5193 8 edematous edematous JJ cord-022526-j9kg00qf 5193 9 , , , cord-022526-j9kg00qf 5193 10 fluid fluid JJ cord-022526-j9kg00qf 5193 11 leaking leaking NN cord-022526-j9kg00qf 5193 12 through through IN cord-022526-j9kg00qf 5193 13 the the DT cord-022526-j9kg00qf 5193 14 serosa serosa NNP cord-022526-j9kg00qf 5193 15 into into IN cord-022526-j9kg00qf 5193 16 the the DT cord-022526-j9kg00qf 5193 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5193 18 fluid fluid NN cord-022526-j9kg00qf 5193 19 increases increase VBZ cord-022526-j9kg00qf 5193 20 the the DT cord-022526-j9kg00qf 5193 21 protein protein NN cord-022526-j9kg00qf 5193 22 concentration concentration NN cord-022526-j9kg00qf 5193 23 . . . cord-022526-j9kg00qf 5194 1 Surgical surgical JJ cord-022526-j9kg00qf 5194 2 correction correction NN cord-022526-j9kg00qf 5194 3 of of IN cord-022526-j9kg00qf 5194 4 colon colon NN cord-022526-j9kg00qf 5194 5 displacement displacement NN cord-022526-j9kg00qf 5194 6 is be VBZ cord-022526-j9kg00qf 5194 7 the the DT cord-022526-j9kg00qf 5194 8 most most RBS cord-022526-j9kg00qf 5194 9 effective effective JJ cord-022526-j9kg00qf 5194 10 means mean NNS cord-022526-j9kg00qf 5194 11 of of IN cord-022526-j9kg00qf 5194 12 resolving resolve VBG cord-022526-j9kg00qf 5194 13 this this DT cord-022526-j9kg00qf 5194 14 disorder disorder NN cord-022526-j9kg00qf 5194 15 . . . cord-022526-j9kg00qf 5195 1 However however RB cord-022526-j9kg00qf 5195 2 , , , cord-022526-j9kg00qf 5195 3 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5195 4 intervention intervention NN cord-022526-j9kg00qf 5195 5 has have VBZ cord-022526-j9kg00qf 5195 6 been be VBN cord-022526-j9kg00qf 5195 7 successful successful JJ cord-022526-j9kg00qf 5195 8 in in IN cord-022526-j9kg00qf 5195 9 select select JJ cord-022526-j9kg00qf 5195 10 cases case NNS cord-022526-j9kg00qf 5195 11 of of IN cord-022526-j9kg00qf 5195 12 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5195 13 entrapment entrapment NN cord-022526-j9kg00qf 5195 14 of of IN cord-022526-j9kg00qf 5195 15 the the DT cord-022526-j9kg00qf 5195 16 large large JJ cord-022526-j9kg00qf 5195 17 colon colon NN cord-022526-j9kg00qf 5195 18 . . . cord-022526-j9kg00qf 5196 1 [ [ -LRB- cord-022526-j9kg00qf 5196 2 106 106 CD cord-022526-j9kg00qf 5196 3 ] ] -RRB- cord-022526-j9kg00qf 5196 4 [ [ -LRB- cord-022526-j9kg00qf 5196 5 107 107 CD cord-022526-j9kg00qf 5196 6 ] ] -RRB- cord-022526-j9kg00qf 5197 1 [ [ -LRB- cord-022526-j9kg00qf 5197 2 108 108 CD cord-022526-j9kg00qf 5197 3 ] ] -RRB- cord-022526-j9kg00qf 5197 4 Before before IN cord-022526-j9kg00qf 5197 5 attempting attempt VBG cord-022526-j9kg00qf 5197 6 such such JJ cord-022526-j9kg00qf 5197 7 manipulations manipulation NNS cord-022526-j9kg00qf 5197 8 , , , cord-022526-j9kg00qf 5197 9 the the DT cord-022526-j9kg00qf 5197 10 clinician clinician NN cord-022526-j9kg00qf 5197 11 must must MD cord-022526-j9kg00qf 5197 12 be be VB cord-022526-j9kg00qf 5197 13 certain certain JJ cord-022526-j9kg00qf 5197 14 of of IN cord-022526-j9kg00qf 5197 15 a a DT cord-022526-j9kg00qf 5197 16 diagnosis diagnosis NN cord-022526-j9kg00qf 5197 17 . . . cord-022526-j9kg00qf 5198 1 One one CD cord-022526-j9kg00qf 5198 2 anesthetizes anesthetizes VBP cord-022526-j9kg00qf 5198 3 the the DT cord-022526-j9kg00qf 5198 4 horse horse NN cord-022526-j9kg00qf 5198 5 and and CC cord-022526-j9kg00qf 5198 6 places place VBZ cord-022526-j9kg00qf 5198 7 it -PRON- PRP cord-022526-j9kg00qf 5198 8 in in IN cord-022526-j9kg00qf 5198 9 right right JJ cord-022526-j9kg00qf 5198 10 lateral lateral JJ cord-022526-j9kg00qf 5198 11 recumbency recumbency NN cord-022526-j9kg00qf 5198 12 , , , cord-022526-j9kg00qf 5198 13 rotates rotate VBZ cord-022526-j9kg00qf 5198 14 the the DT cord-022526-j9kg00qf 5198 15 horse horse NN cord-022526-j9kg00qf 5198 16 up up RP cord-022526-j9kg00qf 5198 17 to to IN cord-022526-j9kg00qf 5198 18 dorsal dorsal JJ cord-022526-j9kg00qf 5198 19 recumbency recumbency NN cord-022526-j9kg00qf 5198 20 , , , cord-022526-j9kg00qf 5198 21 rocking rock VBG cord-022526-j9kg00qf 5198 22 it -PRON- PRP cord-022526-j9kg00qf 5198 23 back back RB cord-022526-j9kg00qf 5198 24 and and CC cord-022526-j9kg00qf 5198 25 forth forth RB cord-022526-j9kg00qf 5198 26 for for IN cord-022526-j9kg00qf 5198 27 5 5 CD cord-022526-j9kg00qf 5198 28 to to TO cord-022526-j9kg00qf 5198 29 10 10 CD cord-022526-j9kg00qf 5198 30 minutes minute NNS cord-022526-j9kg00qf 5198 31 , , , cord-022526-j9kg00qf 5198 32 and and CC cord-022526-j9kg00qf 5198 33 then then RB cord-022526-j9kg00qf 5198 34 rolls roll VBZ cord-022526-j9kg00qf 5198 35 the the DT cord-022526-j9kg00qf 5198 36 horse horse NN cord-022526-j9kg00qf 5198 37 down down RP cord-022526-j9kg00qf 5198 38 into into IN cord-022526-j9kg00qf 5198 39 left left JJ cord-022526-j9kg00qf 5198 40 lateral lateral JJ cord-022526-j9kg00qf 5198 41 recumbency recumbency NN cord-022526-j9kg00qf 5198 42 . . . cord-022526-j9kg00qf 5199 1 109 109 CD cord-022526-j9kg00qf 5199 2 One one PRP cord-022526-j9kg00qf 5199 3 should should MD cord-022526-j9kg00qf 5199 4 palpate palpate VB cord-022526-j9kg00qf 5199 5 the the DT cord-022526-j9kg00qf 5199 6 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5199 7 space space NN cord-022526-j9kg00qf 5199 8 per per IN cord-022526-j9kg00qf 5199 9 rectum rectum NN cord-022526-j9kg00qf 5199 10 to to TO cord-022526-j9kg00qf 5199 11 determine determine VB cord-022526-j9kg00qf 5199 12 whether whether IN cord-022526-j9kg00qf 5199 13 the the DT cord-022526-j9kg00qf 5199 14 entrapment entrapment NN cord-022526-j9kg00qf 5199 15 has have VBZ cord-022526-j9kg00qf 5199 16 been be VBN cord-022526-j9kg00qf 5199 17 relieved relieve VBN cord-022526-j9kg00qf 5199 18 before before IN cord-022526-j9kg00qf 5199 19 recovering recover VBG cord-022526-j9kg00qf 5199 20 the the DT cord-022526-j9kg00qf 5199 21 horse horse NN cord-022526-j9kg00qf 5199 22 from from IN cord-022526-j9kg00qf 5199 23 anesthesia anesthesia NN cord-022526-j9kg00qf 5199 24 . . . cord-022526-j9kg00qf 5200 1 One one PRP cord-022526-j9kg00qf 5200 2 may may MD cord-022526-j9kg00qf 5200 3 administer administer VB cord-022526-j9kg00qf 5200 4 phenylephrine phenylephrine NNP cord-022526-j9kg00qf 5200 5 ( ( -LRB- cord-022526-j9kg00qf 5200 6 3 3 CD cord-022526-j9kg00qf 5200 7 - - SYM cord-022526-j9kg00qf 5200 8 6 6 CD cord-022526-j9kg00qf 5200 9 µg µg NN cord-022526-j9kg00qf 5200 10 / / SYM cord-022526-j9kg00qf 5200 11 kg kg NNP cord-022526-j9kg00qf 5200 12 / / SYM cord-022526-j9kg00qf 5200 13 min min NN cord-022526-j9kg00qf 5200 14 over over IN cord-022526-j9kg00qf 5200 15 15 15 CD cord-022526-j9kg00qf 5200 16 minutes minute NNS cord-022526-j9kg00qf 5200 17 ) ) -RRB- cord-022526-j9kg00qf 5200 18 to to TO cord-022526-j9kg00qf 5200 19 decrease decrease VB cord-022526-j9kg00qf 5200 20 the the DT cord-022526-j9kg00qf 5200 21 size size NN cord-022526-j9kg00qf 5200 22 of of IN cord-022526-j9kg00qf 5200 23 the the DT cord-022526-j9kg00qf 5200 24 spleen spleen NN cord-022526-j9kg00qf 5200 25 . . . cord-022526-j9kg00qf 5201 1 110 110 CD cord-022526-j9kg00qf 5202 1 More more RBR cord-022526-j9kg00qf 5202 2 recently recently RB cord-022526-j9kg00qf 5202 3 , , , cord-022526-j9kg00qf 5202 4 phenylephrine phenylephrine NNP cord-022526-j9kg00qf 5202 5 has have VBZ cord-022526-j9kg00qf 5202 6 been be VBN cord-022526-j9kg00qf 5202 7 used use VBN cord-022526-j9kg00qf 5202 8 successfully successfully RB cord-022526-j9kg00qf 5202 9 with with IN cord-022526-j9kg00qf 5202 10 30 30 CD cord-022526-j9kg00qf 5202 11 to to TO cord-022526-j9kg00qf 5202 12 45 45 CD cord-022526-j9kg00qf 5202 13 minutes minute NNS cord-022526-j9kg00qf 5202 14 of of IN cord-022526-j9kg00qf 5202 15 exercise exercise NN cord-022526-j9kg00qf 5202 16 to to TO cord-022526-j9kg00qf 5202 17 reduce reduce VB cord-022526-j9kg00qf 5202 18 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5202 19 entrapments entrapment NNS cord-022526-j9kg00qf 5202 20 in in IN cord-022526-j9kg00qf 5202 21 four four CD cord-022526-j9kg00qf 5202 22 of of IN cord-022526-j9kg00qf 5202 23 six six CD cord-022526-j9kg00qf 5202 24 horses horse NNS cord-022526-j9kg00qf 5202 25 . . . cord-022526-j9kg00qf 5203 1 26 26 CD cord-022526-j9kg00qf 5204 1 The the DT cord-022526-j9kg00qf 5204 2 authors author NNS cord-022526-j9kg00qf 5204 3 suggested suggest VBD cord-022526-j9kg00qf 5204 4 that that IN cord-022526-j9kg00qf 5204 5 the the DT cord-022526-j9kg00qf 5204 6 technique technique NN cord-022526-j9kg00qf 5204 7 be be VB cord-022526-j9kg00qf 5204 8 used use VBN cord-022526-j9kg00qf 5204 9 on on IN cord-022526-j9kg00qf 5204 10 horses horse NNS cord-022526-j9kg00qf 5204 11 with with IN cord-022526-j9kg00qf 5204 12 mild mild JJ cord-022526-j9kg00qf 5204 13 to to TO cord-022526-j9kg00qf 5204 14 moderate moderate JJ cord-022526-j9kg00qf 5204 15 colonic colonic JJ cord-022526-j9kg00qf 5204 16 distention distention NN cord-022526-j9kg00qf 5204 17 , , , cord-022526-j9kg00qf 5204 18 particularly particularly RB cord-022526-j9kg00qf 5204 19 when when WRB cord-022526-j9kg00qf 5204 20 financial financial JJ cord-022526-j9kg00qf 5204 21 constraints constraint NNS cord-022526-j9kg00qf 5204 22 are be VBP cord-022526-j9kg00qf 5204 23 severe severe JJ cord-022526-j9kg00qf 5204 24 . . . cord-022526-j9kg00qf 5205 1 A a DT cord-022526-j9kg00qf 5205 2 number number NN cord-022526-j9kg00qf 5205 3 of of IN cord-022526-j9kg00qf 5205 4 cases case NNS cord-022526-j9kg00qf 5205 5 occur occur VBP cord-022526-j9kg00qf 5205 6 in in IN cord-022526-j9kg00qf 5205 7 which which WDT cord-022526-j9kg00qf 5205 8 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5205 9 interventions intervention NNS cord-022526-j9kg00qf 5205 10 do do VBP cord-022526-j9kg00qf 5205 11 not not RB cord-022526-j9kg00qf 5205 12 correct correct VB cord-022526-j9kg00qf 5205 13 the the DT cord-022526-j9kg00qf 5205 14 problem problem NN cord-022526-j9kg00qf 5205 15 and and CC cord-022526-j9kg00qf 5205 16 others other NNS cord-022526-j9kg00qf 5205 17 in in IN cord-022526-j9kg00qf 5205 18 which which WDT cord-022526-j9kg00qf 5205 19 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5205 20 manipulations manipulation NNS cord-022526-j9kg00qf 5205 21 correct correct VBP cord-022526-j9kg00qf 5205 22 the the DT cord-022526-j9kg00qf 5205 23 entrapment entrapment NN cord-022526-j9kg00qf 5205 24 but but CC cord-022526-j9kg00qf 5205 25 result result NN cord-022526-j9kg00qf 5205 26 in in IN cord-022526-j9kg00qf 5205 27 large large JJ cord-022526-j9kg00qf 5205 28 colon colon NN cord-022526-j9kg00qf 5205 29 volvulus volvulus NN cord-022526-j9kg00qf 5205 30 or or CC cord-022526-j9kg00qf 5205 31 displacement displacement NN cord-022526-j9kg00qf 5205 32 . . . cord-022526-j9kg00qf 5206 1 111 111 CD cord-022526-j9kg00qf 5207 1 One one PRP cord-022526-j9kg00qf 5207 2 should should MD cord-022526-j9kg00qf 5207 3 take take VB cord-022526-j9kg00qf 5207 4 horses horse NNS cord-022526-j9kg00qf 5207 5 in in IN cord-022526-j9kg00qf 5207 6 such such JJ cord-022526-j9kg00qf 5207 7 condition condition NN cord-022526-j9kg00qf 5207 8 to to IN cord-022526-j9kg00qf 5207 9 surgery surgery NN cord-022526-j9kg00qf 5207 10 promptly promptly RB cord-022526-j9kg00qf 5207 11 . . . cord-022526-j9kg00qf 5208 1 The the DT cord-022526-j9kg00qf 5208 2 prognosis prognosis NN cord-022526-j9kg00qf 5208 3 for for IN cord-022526-j9kg00qf 5208 4 horses horse NNS cord-022526-j9kg00qf 5208 5 with with IN cord-022526-j9kg00qf 5208 6 large large JJ cord-022526-j9kg00qf 5208 7 colon colon NN cord-022526-j9kg00qf 5208 8 displacement displacement NN cord-022526-j9kg00qf 5208 9 is be VBZ cord-022526-j9kg00qf 5208 10 good good JJ cord-022526-j9kg00qf 5208 11 . . . cord-022526-j9kg00qf 5209 1 In in IN cord-022526-j9kg00qf 5209 2 one one CD cord-022526-j9kg00qf 5209 3 study study NN cord-022526-j9kg00qf 5209 4 on on IN cord-022526-j9kg00qf 5209 5 horses horse NNS cord-022526-j9kg00qf 5209 6 with with IN cord-022526-j9kg00qf 5209 7 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5209 8 entrapment entrapment NN cord-022526-j9kg00qf 5209 9 of of IN cord-022526-j9kg00qf 5209 10 the the DT cord-022526-j9kg00qf 5209 11 large large JJ cord-022526-j9kg00qf 5209 12 colon colon NN cord-022526-j9kg00qf 5209 13 , , , cord-022526-j9kg00qf 5209 14 survival survival NN cord-022526-j9kg00qf 5209 15 exceeded exceed VBD cord-022526-j9kg00qf 5209 16 90 90 CD cord-022526-j9kg00qf 5209 17 % % NN cord-022526-j9kg00qf 5209 18 . . . cord-022526-j9kg00qf 5210 1 108 108 CD cord-022526-j9kg00qf 5211 1 The the DT cord-022526-j9kg00qf 5211 2 horse horse NN cord-022526-j9kg00qf 5211 3 , , , cord-022526-j9kg00qf 5211 4 particularly particularly RB cord-022526-j9kg00qf 5211 5 young young JJ cord-022526-j9kg00qf 5211 6 horses horse NNS cord-022526-j9kg00qf 5211 7 , , , cord-022526-j9kg00qf 5211 8 may may MD cord-022526-j9kg00qf 5211 9 ingest ingest VB cord-022526-j9kg00qf 5211 10 foreign foreign JJ cord-022526-j9kg00qf 5211 11 material material NN cord-022526-j9kg00qf 5211 12 that that WDT cord-022526-j9kg00qf 5211 13 can can MD cord-022526-j9kg00qf 5211 14 cause cause VB cord-022526-j9kg00qf 5211 15 obstruction obstruction NN cord-022526-j9kg00qf 5211 16 , , , cord-022526-j9kg00qf 5211 17 such such JJ cord-022526-j9kg00qf 5211 18 as as IN cord-022526-j9kg00qf 5211 19 bedding bedding NN cord-022526-j9kg00qf 5211 20 , , , cord-022526-j9kg00qf 5211 21 rope rope NN cord-022526-j9kg00qf 5211 22 , , , cord-022526-j9kg00qf 5211 23 plastic plastic NN cord-022526-j9kg00qf 5211 24 , , , cord-022526-j9kg00qf 5211 25 fence fence NN cord-022526-j9kg00qf 5211 26 material material NN cord-022526-j9kg00qf 5211 27 , , , cord-022526-j9kg00qf 5211 28 and and CC cord-022526-j9kg00qf 5211 29 feedbags feedbags NNP cord-022526-j9kg00qf 5211 30 . . . cord-022526-j9kg00qf 5212 1 These these DT cord-022526-j9kg00qf 5212 2 foreign foreign JJ cord-022526-j9kg00qf 5212 3 bodies body NNS cord-022526-j9kg00qf 5212 4 may may MD cord-022526-j9kg00qf 5212 5 result result VB cord-022526-j9kg00qf 5212 6 in in IN cord-022526-j9kg00qf 5212 7 impaction impaction NN cord-022526-j9kg00qf 5212 8 with with IN cord-022526-j9kg00qf 5212 9 ingesta ingesta NNS cord-022526-j9kg00qf 5212 10 and and CC cord-022526-j9kg00qf 5212 11 distention distention NN cord-022526-j9kg00qf 5212 12 of of IN cord-022526-j9kg00qf 5212 13 the the DT cord-022526-j9kg00qf 5212 14 intestine intestine NN cord-022526-j9kg00qf 5212 15 , , , cord-022526-j9kg00qf 5212 16 typically typically RB cord-022526-j9kg00qf 5212 17 in in IN cord-022526-j9kg00qf 5212 18 the the DT cord-022526-j9kg00qf 5212 19 transverse transverse JJ cord-022526-j9kg00qf 5212 20 or or CC cord-022526-j9kg00qf 5212 21 descending descend VBG cord-022526-j9kg00qf 5212 22 colon colon NN cord-022526-j9kg00qf 5212 23 . . . cord-022526-j9kg00qf 5213 1 Young young JJ cord-022526-j9kg00qf 5213 2 horses horse NNS cord-022526-j9kg00qf 5213 3 usually usually RB cord-022526-j9kg00qf 5213 4 are be VBP cord-022526-j9kg00qf 5213 5 affected affect VBN cord-022526-j9kg00qf 5213 6 . . . cord-022526-j9kg00qf 5214 1 In in IN cord-022526-j9kg00qf 5214 2 one one CD cord-022526-j9kg00qf 5214 3 study study NN cord-022526-j9kg00qf 5214 4 the the DT cord-022526-j9kg00qf 5214 5 obstructing obstruct VBG cord-022526-j9kg00qf 5214 6 mass mass NN cord-022526-j9kg00qf 5214 7 could could MD cord-022526-j9kg00qf 5214 8 be be VB cord-022526-j9kg00qf 5214 9 palpated palpate VBN cord-022526-j9kg00qf 5214 10 per per IN cord-022526-j9kg00qf 5214 11 rectum rectum NN cord-022526-j9kg00qf 5214 12 in in IN cord-022526-j9kg00qf 5214 13 three three CD cord-022526-j9kg00qf 5214 14 of of IN cord-022526-j9kg00qf 5214 15 six six CD cord-022526-j9kg00qf 5214 16 horses horse NNS cord-022526-j9kg00qf 5214 17 . . . cord-022526-j9kg00qf 5215 1 112 112 CD cord-022526-j9kg00qf 5215 2 Fecaliths fecalith NNS cord-022526-j9kg00qf 5215 3 are be VBP cord-022526-j9kg00qf 5215 4 common common JJ cord-022526-j9kg00qf 5215 5 in in IN cord-022526-j9kg00qf 5215 6 ponies pony NNS cord-022526-j9kg00qf 5215 7 , , , cord-022526-j9kg00qf 5215 8 miniature miniature JJ cord-022526-j9kg00qf 5215 9 horses horse NNS cord-022526-j9kg00qf 5215 10 , , , cord-022526-j9kg00qf 5215 11 and and CC cord-022526-j9kg00qf 5215 12 foals foal NNS cord-022526-j9kg00qf 5215 13 . . . cord-022526-j9kg00qf 5216 1 113 113 CD cord-022526-j9kg00qf 5217 1 Older old JJR cord-022526-j9kg00qf 5217 2 horses horse NNS cord-022526-j9kg00qf 5217 3 with with IN cord-022526-j9kg00qf 5217 4 poor poor JJ cord-022526-j9kg00qf 5217 5 dentition dentition NN cord-022526-j9kg00qf 5217 6 also also RB cord-022526-j9kg00qf 5217 7 may may MD cord-022526-j9kg00qf 5217 8 be be VB cord-022526-j9kg00qf 5217 9 predisposed predisposed JJ cord-022526-j9kg00qf 5217 10 to to IN cord-022526-j9kg00qf 5217 11 fecaliths fecalith NNS cord-022526-j9kg00qf 5217 12 because because IN cord-022526-j9kg00qf 5217 13 of of IN cord-022526-j9kg00qf 5217 14 the the DT cord-022526-j9kg00qf 5217 15 inability inability NN cord-022526-j9kg00qf 5217 16 to to TO cord-022526-j9kg00qf 5217 17 masticate masticate VB cord-022526-j9kg00qf 5217 18 fibrous fibrous JJ cord-022526-j9kg00qf 5217 19 feed feed NN cord-022526-j9kg00qf 5217 20 material material NN cord-022526-j9kg00qf 5217 21 fully fully RB cord-022526-j9kg00qf 5217 22 . . . cord-022526-j9kg00qf 5218 1 Fecaliths Fecaliths NNP cord-022526-j9kg00qf 5218 2 commonly commonly RB cord-022526-j9kg00qf 5218 3 cause cause VBP cord-022526-j9kg00qf 5218 4 obstruction obstruction NN cord-022526-j9kg00qf 5218 5 in in IN cord-022526-j9kg00qf 5218 6 the the DT cord-022526-j9kg00qf 5218 7 descending descend VBG cord-022526-j9kg00qf 5218 8 colon colon NN cord-022526-j9kg00qf 5218 9 and and CC cord-022526-j9kg00qf 5218 10 may may MD cord-022526-j9kg00qf 5218 11 cause cause VB cord-022526-j9kg00qf 5218 12 tenesmus tenesmus NNP cord-022526-j9kg00qf 5218 13 . . . cord-022526-j9kg00qf 5219 1 112 112 CD cord-022526-j9kg00qf 5220 1 Other other JJ cord-022526-j9kg00qf 5220 2 clinical clinical JJ cord-022526-j9kg00qf 5220 3 signs sign NNS cord-022526-j9kg00qf 5220 4 are be VBP cord-022526-j9kg00qf 5220 5 similar similar JJ cord-022526-j9kg00qf 5220 6 to to IN cord-022526-j9kg00qf 5220 7 those those DT cord-022526-j9kg00qf 5220 8 of of IN cord-022526-j9kg00qf 5220 9 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5220 10 . . . cord-022526-j9kg00qf 5221 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5221 2 radiography radiography NN cord-022526-j9kg00qf 5221 3 may may MD cord-022526-j9kg00qf 5221 4 be be VB cord-022526-j9kg00qf 5221 5 useful useful JJ cord-022526-j9kg00qf 5221 6 in in IN cord-022526-j9kg00qf 5221 7 smaller small JJR cord-022526-j9kg00qf 5221 8 patients patient NNS cord-022526-j9kg00qf 5221 9 to to TO cord-022526-j9kg00qf 5221 10 identify identify VB cord-022526-j9kg00qf 5221 11 the the DT cord-022526-j9kg00qf 5221 12 obstruction obstruction NN cord-022526-j9kg00qf 5221 13 , , , cord-022526-j9kg00qf 5221 14 especially especially RB cord-022526-j9kg00qf 5221 15 if if IN cord-022526-j9kg00qf 5221 16 gas gas NN cord-022526-j9kg00qf 5221 17 distention distention NN cord-022526-j9kg00qf 5221 18 around around IN cord-022526-j9kg00qf 5221 19 the the DT cord-022526-j9kg00qf 5221 20 foreign foreign JJ cord-022526-j9kg00qf 5221 21 body body NN cord-022526-j9kg00qf 5221 22 or or CC cord-022526-j9kg00qf 5221 23 fecalith fecalith NN cord-022526-j9kg00qf 5221 24 provides provide VBZ cord-022526-j9kg00qf 5221 25 contrast contrast NN cord-022526-j9kg00qf 5221 26 . . . cord-022526-j9kg00qf 5222 1 The the DT cord-022526-j9kg00qf 5222 2 horse horse NN cord-022526-j9kg00qf 5222 3 usually usually RB cord-022526-j9kg00qf 5222 4 requires require VBZ cord-022526-j9kg00qf 5222 5 surgical surgical JJ cord-022526-j9kg00qf 5222 6 treatment treatment NN cord-022526-j9kg00qf 5222 7 . . . cord-022526-j9kg00qf 5223 1 Mural mural NN cord-022526-j9kg00qf 5223 2 masses masse NNS cord-022526-j9kg00qf 5223 3 such such JJ cord-022526-j9kg00qf 5223 4 as as IN cord-022526-j9kg00qf 5223 5 abscesses abscess NNS cord-022526-j9kg00qf 5223 6 , , , cord-022526-j9kg00qf 5223 7 tumors tumor NNS cord-022526-j9kg00qf 5223 8 ( ( -LRB- cord-022526-j9kg00qf 5223 9 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5223 10 , , , cord-022526-j9kg00qf 5223 11 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5223 12 ) ) -RRB- cord-022526-j9kg00qf 5223 13 , , , cord-022526-j9kg00qf 5223 14 granulomata granulomata NNP cord-022526-j9kg00qf 5223 15 , , , cord-022526-j9kg00qf 5223 16 and and CC cord-022526-j9kg00qf 5223 17 hematomas hematoma NNS cord-022526-j9kg00qf 5223 18 ( ( -LRB- cord-022526-j9kg00qf 5223 19 Figure figure NN cord-022526-j9kg00qf 5223 20 13 13 CD cord-022526-j9kg00qf 5223 21 .15 .15 CD cord-022526-j9kg00qf 5223 22 - - SYM cord-022526-j9kg00qf 5223 23 4 4 CD cord-022526-j9kg00qf 5223 24 ) ) -RRB- cord-022526-j9kg00qf 5223 25 can can MD cord-022526-j9kg00qf 5223 26 cause cause VB cord-022526-j9kg00qf 5223 27 luminal luminal JJ cord-022526-j9kg00qf 5223 28 obstruction obstruction NN cord-022526-j9kg00qf 5223 29 and and CC cord-022526-j9kg00qf 5223 30 impaction impaction NN cord-022526-j9kg00qf 5223 31 , , , cord-022526-j9kg00qf 5223 32 typically typically RB cord-022526-j9kg00qf 5223 33 in in IN cord-022526-j9kg00qf 5223 34 older old JJR cord-022526-j9kg00qf 5223 35 horses horse NNS cord-022526-j9kg00qf 5223 36 . . . cord-022526-j9kg00qf 5224 1 Impaction impaction NN cord-022526-j9kg00qf 5224 2 may may MD cord-022526-j9kg00qf 5224 3 result result VB cord-022526-j9kg00qf 5224 4 from from IN cord-022526-j9kg00qf 5224 5 obstruction obstruction NN cord-022526-j9kg00qf 5224 6 of of IN cord-022526-j9kg00qf 5224 7 the the DT cord-022526-j9kg00qf 5224 8 lumen lumen NN cord-022526-j9kg00qf 5224 9 or or CC cord-022526-j9kg00qf 5224 10 impaired impaired JJ cord-022526-j9kg00qf 5224 11 motility motility NN cord-022526-j9kg00qf 5224 12 in in IN cord-022526-j9kg00qf 5224 13 the the DT cord-022526-j9kg00qf 5224 14 segment segment NN cord-022526-j9kg00qf 5224 15 of of IN cord-022526-j9kg00qf 5224 16 intestine intestine NN cord-022526-j9kg00qf 5224 17 with with IN cord-022526-j9kg00qf 5224 18 the the DT cord-022526-j9kg00qf 5224 19 mass mass NN cord-022526-j9kg00qf 5224 20 . . . cord-022526-j9kg00qf 5225 1 Abscesses abscess NNS cord-022526-j9kg00qf 5225 2 may may MD cord-022526-j9kg00qf 5225 3 originate originate VB cord-022526-j9kg00qf 5225 4 from from IN cord-022526-j9kg00qf 5225 5 the the DT cord-022526-j9kg00qf 5225 6 lumen lumen NN cord-022526-j9kg00qf 5225 7 of of IN cord-022526-j9kg00qf 5225 8 the the DT cord-022526-j9kg00qf 5225 9 intestine intestine NN cord-022526-j9kg00qf 5225 10 or or CC cord-022526-j9kg00qf 5225 11 may may MD cord-022526-j9kg00qf 5225 12 extend extend VB cord-022526-j9kg00qf 5225 13 from from IN cord-022526-j9kg00qf 5225 14 the the DT cord-022526-j9kg00qf 5225 15 mesentery mesentery NN cord-022526-j9kg00qf 5225 16 or or CC cord-022526-j9kg00qf 5225 17 mesenteric mesenteric JJ cord-022526-j9kg00qf 5225 18 lymph lymph NN cord-022526-j9kg00qf 5225 19 nodes node NNS cord-022526-j9kg00qf 5225 20 . . . cord-022526-j9kg00qf 5226 1 Intramural intramural JJ cord-022526-j9kg00qf 5226 2 hematomas hematoma NNS cord-022526-j9kg00qf 5226 3 form form VBP cord-022526-j9kg00qf 5226 4 most most RBS cord-022526-j9kg00qf 5226 5 commonly commonly RB cord-022526-j9kg00qf 5226 6 in in IN cord-022526-j9kg00qf 5226 7 the the DT cord-022526-j9kg00qf 5226 8 descending descend VBG cord-022526-j9kg00qf 5226 9 colon colon NN cord-022526-j9kg00qf 5226 10 and and CC cord-022526-j9kg00qf 5226 11 cause cause VB cord-022526-j9kg00qf 5226 12 acute acute JJ cord-022526-j9kg00qf 5226 13 abdominal abdominal JJ cord-022526-j9kg00qf 5226 14 pain pain NN cord-022526-j9kg00qf 5226 15 . . . cord-022526-j9kg00qf 5227 1 114 114 CD cord-022526-j9kg00qf 5228 1 Once once IN cord-022526-j9kg00qf 5228 2 the the DT cord-022526-j9kg00qf 5228 3 acute acute JJ cord-022526-j9kg00qf 5228 4 pain pain NN cord-022526-j9kg00qf 5228 5 from from IN cord-022526-j9kg00qf 5228 6 the the DT cord-022526-j9kg00qf 5228 7 hematoma hematoma NN cord-022526-j9kg00qf 5228 8 subsides subside VBZ cord-022526-j9kg00qf 5228 9 , , , cord-022526-j9kg00qf 5228 10 impaction impaction NN cord-022526-j9kg00qf 5228 11 proximal proximal JJ cord-022526-j9kg00qf 5228 12 to to IN cord-022526-j9kg00qf 5228 13 the the DT cord-022526-j9kg00qf 5228 14 hematoma hematoma NN cord-022526-j9kg00qf 5228 15 develops develop VBZ cord-022526-j9kg00qf 5228 16 because because IN cord-022526-j9kg00qf 5228 17 of of IN cord-022526-j9kg00qf 5228 18 impaired impaired JJ cord-022526-j9kg00qf 5228 19 motility motility NN cord-022526-j9kg00qf 5228 20 through through IN cord-022526-j9kg00qf 5228 21 the the DT cord-022526-j9kg00qf 5228 22 affected affected JJ cord-022526-j9kg00qf 5228 23 portion portion NN cord-022526-j9kg00qf 5228 24 of of IN cord-022526-j9kg00qf 5228 25 the the DT cord-022526-j9kg00qf 5228 26 colon colon NN cord-022526-j9kg00qf 5228 27 . . . cord-022526-j9kg00qf 5229 1 Trauma trauma NN cord-022526-j9kg00qf 5229 2 , , , cord-022526-j9kg00qf 5229 3 ulceration ulceration NN cord-022526-j9kg00qf 5229 4 of of IN cord-022526-j9kg00qf 5229 5 the the DT cord-022526-j9kg00qf 5229 6 mucosa mucosa NN cord-022526-j9kg00qf 5229 7 , , , cord-022526-j9kg00qf 5229 8 and and CC cord-022526-j9kg00qf 5229 9 parasitic parasitic JJ cord-022526-j9kg00qf 5229 10 damage damage NN cord-022526-j9kg00qf 5229 11 are be VBP cord-022526-j9kg00qf 5229 12 speculated speculate VBN cord-022526-j9kg00qf 5229 13 causes cause NNS cord-022526-j9kg00qf 5229 14 of of IN cord-022526-j9kg00qf 5229 15 intramural intramural JJ cord-022526-j9kg00qf 5229 16 hematomas hematoma NNS cord-022526-j9kg00qf 5229 17 . . . cord-022526-j9kg00qf 5230 1 114 114 CD cord-022526-j9kg00qf 5230 2 , , , cord-022526-j9kg00qf 5230 3 115 115 CD cord-022526-j9kg00qf 5230 4 Stricture stricture NN cord-022526-j9kg00qf 5230 5 of of IN cord-022526-j9kg00qf 5230 6 the the DT cord-022526-j9kg00qf 5230 7 large large JJ cord-022526-j9kg00qf 5230 8 intestine intestine NN cord-022526-j9kg00qf 5230 9 occurs occur VBZ cord-022526-j9kg00qf 5230 10 when when WRB cord-022526-j9kg00qf 5230 11 fibrous fibrous JJ cord-022526-j9kg00qf 5230 12 tissue tissue NN cord-022526-j9kg00qf 5230 13 forms form NNS cord-022526-j9kg00qf 5230 14 in in IN cord-022526-j9kg00qf 5230 15 a a DT cord-022526-j9kg00qf 5230 16 circular circular JJ cord-022526-j9kg00qf 5230 17 pattern pattern NN cord-022526-j9kg00qf 5230 18 around around RB cord-022526-j9kg00qf 5230 19 or or CC cord-022526-j9kg00qf 5230 20 within within IN cord-022526-j9kg00qf 5230 21 the the DT cord-022526-j9kg00qf 5230 22 intestine intestine NN cord-022526-j9kg00qf 5230 23 , , , cord-022526-j9kg00qf 5230 24 reducing reduce VBG cord-022526-j9kg00qf 5230 25 the the DT cord-022526-j9kg00qf 5230 26 luminal luminal JJ cord-022526-j9kg00qf 5230 27 diameter diameter NN cord-022526-j9kg00qf 5230 28 and and CC cord-022526-j9kg00qf 5230 29 the the DT cord-022526-j9kg00qf 5230 30 ability ability NN cord-022526-j9kg00qf 5230 31 of of IN cord-022526-j9kg00qf 5230 32 the the DT cord-022526-j9kg00qf 5230 33 wall wall NN cord-022526-j9kg00qf 5230 34 to to TO cord-022526-j9kg00qf 5230 35 stretch stretch VB cord-022526-j9kg00qf 5230 36 . . . cord-022526-j9kg00qf 5231 1 Strictures stricture NNS cord-022526-j9kg00qf 5231 2 may may MD cord-022526-j9kg00qf 5231 3 be be VB cord-022526-j9kg00qf 5231 4 congenital congenital JJ cord-022526-j9kg00qf 5231 5 or or CC cord-022526-j9kg00qf 5231 6 may may MD cord-022526-j9kg00qf 5231 7 follow follow VB cord-022526-j9kg00qf 5231 8 peritonitis peritonitis NN cord-022526-j9kg00qf 5231 9 , , , cord-022526-j9kg00qf 5231 10 previous previous JJ cord-022526-j9kg00qf 5231 11 abdominal abdominal JJ cord-022526-j9kg00qf 5231 12 surgery surgery NN cord-022526-j9kg00qf 5231 13 , , , cord-022526-j9kg00qf 5231 14 or or CC cord-022526-j9kg00qf 5231 15 inflammatory inflammatory JJ cord-022526-j9kg00qf 5231 16 bowel bowel NN cord-022526-j9kg00qf 5231 17 disease disease NN cord-022526-j9kg00qf 5231 18 . . . cord-022526-j9kg00qf 5232 1 In in IN cord-022526-j9kg00qf 5232 2 a a DT cord-022526-j9kg00qf 5232 3 report report NN cord-022526-j9kg00qf 5232 4 of of IN cord-022526-j9kg00qf 5232 5 11 11 CD cord-022526-j9kg00qf 5232 6 horses horse NNS cord-022526-j9kg00qf 5232 7 with with IN cord-022526-j9kg00qf 5232 8 inflammatory inflammatory JJ cord-022526-j9kg00qf 5232 9 bowel bowel NN cord-022526-j9kg00qf 5232 10 disease disease NN cord-022526-j9kg00qf 5232 11 , , , cord-022526-j9kg00qf 5232 12 6 6 CD cord-022526-j9kg00qf 5232 13 horses horse NNS cord-022526-j9kg00qf 5232 14 had have VBD cord-022526-j9kg00qf 5232 15 strictures stricture NNS cord-022526-j9kg00qf 5232 16 , , , cord-022526-j9kg00qf 5232 17 four four CD cord-022526-j9kg00qf 5232 18 of of IN cord-022526-j9kg00qf 5232 19 which which WDT cord-022526-j9kg00qf 5232 20 were be VBD cord-022526-j9kg00qf 5232 21 in in IN cord-022526-j9kg00qf 5232 22 the the DT cord-022526-j9kg00qf 5232 23 small small JJ cord-022526-j9kg00qf 5232 24 intestine intestine NN cord-022526-j9kg00qf 5232 25 and and CC cord-022526-j9kg00qf 5232 26 two two CD cord-022526-j9kg00qf 5232 27 of of IN cord-022526-j9kg00qf 5232 28 which which WDT cord-022526-j9kg00qf 5232 29 were be VBD cord-022526-j9kg00qf 5232 30 in in IN cord-022526-j9kg00qf 5232 31 the the DT cord-022526-j9kg00qf 5232 32 large large JJ cord-022526-j9kg00qf 5232 33 colon colon NN cord-022526-j9kg00qf 5232 34 . . . cord-022526-j9kg00qf 5233 1 116 116 CD cord-022526-j9kg00qf 5233 2 Clinical clinical JJ cord-022526-j9kg00qf 5233 3 signs sign NNS cord-022526-j9kg00qf 5233 4 vary vary VBP cord-022526-j9kg00qf 5233 5 according accord VBG cord-022526-j9kg00qf 5233 6 to to IN cord-022526-j9kg00qf 5233 7 the the DT cord-022526-j9kg00qf 5233 8 degree degree NN cord-022526-j9kg00qf 5233 9 of of IN cord-022526-j9kg00qf 5233 10 luminal luminal JJ cord-022526-j9kg00qf 5233 11 obstruction obstruction NN cord-022526-j9kg00qf 5233 12 . . . cord-022526-j9kg00qf 5234 1 Partial partial JJ cord-022526-j9kg00qf 5234 2 obstruction obstruction NN cord-022526-j9kg00qf 5234 3 and and CC cord-022526-j9kg00qf 5234 4 impaction impaction NN cord-022526-j9kg00qf 5234 5 tend tend VB cord-022526-j9kg00qf 5234 6 to to TO cord-022526-j9kg00qf 5234 7 produce produce VB cord-022526-j9kg00qf 5234 8 mild mild JJ cord-022526-j9kg00qf 5234 9 to to TO cord-022526-j9kg00qf 5234 10 moderate moderate JJ cord-022526-j9kg00qf 5234 11 abdominal abdominal JJ cord-022526-j9kg00qf 5234 12 pain pain NN cord-022526-j9kg00qf 5234 13 of of IN cord-022526-j9kg00qf 5234 14 insidious insidious JJ cord-022526-j9kg00qf 5234 15 onset onset NN cord-022526-j9kg00qf 5234 16 . . . cord-022526-j9kg00qf 5235 1 Mural mural NN cord-022526-j9kg00qf 5235 2 hematomas hematoma NNS cord-022526-j9kg00qf 5235 3 tend tend VBP cord-022526-j9kg00qf 5235 4 to to TO cord-022526-j9kg00qf 5235 5 produce produce VB cord-022526-j9kg00qf 5235 6 signs sign NNS cord-022526-j9kg00qf 5235 7 of of IN cord-022526-j9kg00qf 5235 8 acute acute JJ cord-022526-j9kg00qf 5235 9 abdominal abdominal JJ cord-022526-j9kg00qf 5235 10 pain pain NN cord-022526-j9kg00qf 5235 11 . . . cord-022526-j9kg00qf 5236 1 114 114 CD cord-022526-j9kg00qf 5236 2 , , , cord-022526-j9kg00qf 5236 3 115 115 CD cord-022526-j9kg00qf 5236 4 Per per IN cord-022526-j9kg00qf 5236 5 rectal rectal JJ cord-022526-j9kg00qf 5236 6 palpation palpation NN cord-022526-j9kg00qf 5236 7 of of IN cord-022526-j9kg00qf 5236 8 the the DT cord-022526-j9kg00qf 5236 9 abdomen abdomen NN cord-022526-j9kg00qf 5236 10 may may MD cord-022526-j9kg00qf 5236 11 reveal reveal VB cord-022526-j9kg00qf 5236 12 the the DT cord-022526-j9kg00qf 5236 13 presence presence NN cord-022526-j9kg00qf 5236 14 of of IN cord-022526-j9kg00qf 5236 15 a a DT cord-022526-j9kg00qf 5236 16 mass mass NN cord-022526-j9kg00qf 5236 17 or or CC cord-022526-j9kg00qf 5236 18 simply simply RB cord-022526-j9kg00qf 5236 19 the the DT cord-022526-j9kg00qf 5236 20 impacted impact VBN cord-022526-j9kg00qf 5236 21 segment segment NN cord-022526-j9kg00qf 5236 22 but but CC cord-022526-j9kg00qf 5236 23 not not RB cord-022526-j9kg00qf 5236 24 the the DT cord-022526-j9kg00qf 5236 25 mass mass NN cord-022526-j9kg00qf 5236 26 itself -PRON- PRP cord-022526-j9kg00qf 5236 27 . . . cord-022526-j9kg00qf 5237 1 One one CD cord-022526-j9kg00qf 5237 2 may may MD cord-022526-j9kg00qf 5237 3 note note VB cord-022526-j9kg00qf 5237 4 fever fever NN cord-022526-j9kg00qf 5237 5 , , , cord-022526-j9kg00qf 5237 6 weight weight NN cord-022526-j9kg00qf 5237 7 loss loss NN cord-022526-j9kg00qf 5237 8 , , , cord-022526-j9kg00qf 5237 9 and and CC cord-022526-j9kg00qf 5237 10 anorexia anorexia VB cord-022526-j9kg00qf 5237 11 if if IN cord-022526-j9kg00qf 5237 12 an an DT cord-022526-j9kg00qf 5237 13 abscess abscess NN cord-022526-j9kg00qf 5237 14 or or CC cord-022526-j9kg00qf 5237 15 tumor tumor NN cord-022526-j9kg00qf 5237 16 is be VBZ cord-022526-j9kg00qf 5237 17 the the DT cord-022526-j9kg00qf 5237 18 cause cause NN cord-022526-j9kg00qf 5237 19 . . . cord-022526-j9kg00qf 5238 1 An an DT cord-022526-j9kg00qf 5238 2 elevated elevated JJ cord-022526-j9kg00qf 5238 3 white white JJ cord-022526-j9kg00qf 5238 4 blood blood NN cord-022526-j9kg00qf 5238 5 cell cell NN cord-022526-j9kg00qf 5238 6 count count NN cord-022526-j9kg00qf 5238 7 ; ; : cord-022526-j9kg00qf 5238 8 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 5238 9 ; ; : cord-022526-j9kg00qf 5238 10 hyperglobulinemia hyperglobulinemia NNP cord-022526-j9kg00qf 5238 11 ; ; : cord-022526-j9kg00qf 5238 12 or or CC cord-022526-j9kg00qf 5238 13 normocytic normocytic JJ cord-022526-j9kg00qf 5238 14 , , , cord-022526-j9kg00qf 5238 15 normochromic normochromic JJ cord-022526-j9kg00qf 5238 16 anemia anemia NN cord-022526-j9kg00qf 5238 17 may may MD cord-022526-j9kg00qf 5238 18 occur occur VB cord-022526-j9kg00qf 5238 19 with with IN cord-022526-j9kg00qf 5238 20 abscesses abscess NNS cord-022526-j9kg00qf 5238 21 or or CC cord-022526-j9kg00qf 5238 22 tumors tumor NNS cord-022526-j9kg00qf 5238 23 . . . cord-022526-j9kg00qf 5239 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5239 2 fluid fluid NN cord-022526-j9kg00qf 5239 3 may may MD cord-022526-j9kg00qf 5239 4 reflect reflect VB cord-022526-j9kg00qf 5239 5 the the DT cord-022526-j9kg00qf 5239 6 cause cause NN cord-022526-j9kg00qf 5239 7 of of IN cord-022526-j9kg00qf 5239 8 the the DT cord-022526-j9kg00qf 5239 9 mass mass NN cord-022526-j9kg00qf 5239 10 . . . cord-022526-j9kg00qf 5240 1 Tumor tumor NN cord-022526-j9kg00qf 5240 2 cells cell NNS cord-022526-j9kg00qf 5240 3 may may MD cord-022526-j9kg00qf 5240 4 occur occur VB cord-022526-j9kg00qf 5240 5 infrequently infrequently RB cord-022526-j9kg00qf 5240 6 . . . cord-022526-j9kg00qf 5241 1 One one CD cord-022526-j9kg00qf 5241 2 may may MD cord-022526-j9kg00qf 5241 3 note note VB cord-022526-j9kg00qf 5241 4 evidence evidence NN cord-022526-j9kg00qf 5241 5 of of IN cord-022526-j9kg00qf 5241 6 inflammation inflammation NN cord-022526-j9kg00qf 5241 7 with with IN cord-022526-j9kg00qf 5241 8 bacteria bacteria NNS cord-022526-j9kg00qf 5241 9 if if IN cord-022526-j9kg00qf 5241 10 the the DT cord-022526-j9kg00qf 5241 11 cause cause NN cord-022526-j9kg00qf 5241 12 of of IN cord-022526-j9kg00qf 5241 13 colic colic NN cord-022526-j9kg00qf 5241 14 is be VBZ cord-022526-j9kg00qf 5241 15 an an DT cord-022526-j9kg00qf 5241 16 abscess abscess NN cord-022526-j9kg00qf 5241 17 or or CC cord-022526-j9kg00qf 5241 18 granuloma granuloma NN cord-022526-j9kg00qf 5241 19 , , , cord-022526-j9kg00qf 5241 20 in in IN cord-022526-j9kg00qf 5241 21 which which WDT cord-022526-j9kg00qf 5241 22 case case NN cord-022526-j9kg00qf 5241 23 one one PRP cord-022526-j9kg00qf 5241 24 should should MD cord-022526-j9kg00qf 5241 25 culture culture VB cord-022526-j9kg00qf 5241 26 the the DT cord-022526-j9kg00qf 5241 27 fluid fluid NN cord-022526-j9kg00qf 5241 28 . . . cord-022526-j9kg00qf 5242 1 Hematomas Hematomas NNP cord-022526-j9kg00qf 5242 2 may may MD cord-022526-j9kg00qf 5242 3 cause cause VB cord-022526-j9kg00qf 5242 4 hemorrhage hemorrhage NN cord-022526-j9kg00qf 5242 5 into into IN cord-022526-j9kg00qf 5242 6 the the DT cord-022526-j9kg00qf 5242 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 5242 8 fluid fluid NN cord-022526-j9kg00qf 5242 9 . . . cord-022526-j9kg00qf 5243 1 Treatment treatment NN cord-022526-j9kg00qf 5243 2 usually usually RB cord-022526-j9kg00qf 5243 3 requires require VBZ cord-022526-j9kg00qf 5243 4 surgical surgical JJ cord-022526-j9kg00qf 5243 5 resection resection NN cord-022526-j9kg00qf 5243 6 of of IN cord-022526-j9kg00qf 5243 7 the the DT cord-022526-j9kg00qf 5243 8 mass mass NN cord-022526-j9kg00qf 5243 9 . . . cord-022526-j9kg00qf 5244 1 One one CD cord-022526-j9kg00qf 5244 2 may may MD cord-022526-j9kg00qf 5244 3 treat treat VB cord-022526-j9kg00qf 5244 4 abscesses abscess NNS cord-022526-j9kg00qf 5244 5 with with IN cord-022526-j9kg00qf 5244 6 appropriate appropriate JJ cord-022526-j9kg00qf 5244 7 antibiotics antibiotic NNS cord-022526-j9kg00qf 5244 8 if if IN cord-022526-j9kg00qf 5244 9 the the DT cord-022526-j9kg00qf 5244 10 impaction impaction NN cord-022526-j9kg00qf 5244 11 can can MD cord-022526-j9kg00qf 5244 12 be be VB cord-022526-j9kg00qf 5244 13 resolved resolve VBN cord-022526-j9kg00qf 5244 14 medically medically RB cord-022526-j9kg00qf 5244 15 with with IN cord-022526-j9kg00qf 5244 16 oral oral JJ cord-022526-j9kg00qf 5244 17 or or CC cord-022526-j9kg00qf 5244 18 intravenous intravenous JJ cord-022526-j9kg00qf 5244 19 analgesics analgesic NNS cord-022526-j9kg00qf 5244 20 and and CC cord-022526-j9kg00qf 5244 21 laxatives laxative NNS cord-022526-j9kg00qf 5244 22 . . . cord-022526-j9kg00qf 5245 1 Streptococcus streptococcus NN cord-022526-j9kg00qf 5245 2 spp spp NNS cord-022526-j9kg00qf 5245 3 , , , cord-022526-j9kg00qf 5245 4 Actinomyces Actinomyces NNP cord-022526-j9kg00qf 5245 5 pyogenes pyogene NNS cord-022526-j9kg00qf 5245 6 , , , cord-022526-j9kg00qf 5245 7 Corynebacterium Corynebacterium NNP cord-022526-j9kg00qf 5245 8 pseudotuberculosis pseudotuberculosis NN cord-022526-j9kg00qf 5245 9 , , , cord-022526-j9kg00qf 5245 10 Rhodococcus Rhodococcus NNP cord-022526-j9kg00qf 5245 11 equi equi NN cord-022526-j9kg00qf 5245 12 , , , cord-022526-j9kg00qf 5245 13 anaerobic anaerobic JJ cord-022526-j9kg00qf 5245 14 bacteria bacteria NNS cord-022526-j9kg00qf 5245 15 , , , cord-022526-j9kg00qf 5245 16 and and CC cord-022526-j9kg00qf 5245 17 gram gram NN cord-022526-j9kg00qf 5245 18 - - HYPH cord-022526-j9kg00qf 5245 19 negative negative JJ cord-022526-j9kg00qf 5245 20 enteric enteric JJ cord-022526-j9kg00qf 5245 21 organisms organism NNS cord-022526-j9kg00qf 5245 22 commonly commonly RB cord-022526-j9kg00qf 5245 23 are be VBP cord-022526-j9kg00qf 5245 24 involved involve VBN cord-022526-j9kg00qf 5245 25 in in IN cord-022526-j9kg00qf 5245 26 abscesses abscess NNS cord-022526-j9kg00qf 5245 27 . . . cord-022526-j9kg00qf 5246 1 Atresia Atresia NNP cord-022526-j9kg00qf 5246 2 of of IN cord-022526-j9kg00qf 5246 3 a a DT cord-022526-j9kg00qf 5246 4 segment segment NN cord-022526-j9kg00qf 5246 5 of of IN cord-022526-j9kg00qf 5246 6 the the DT cord-022526-j9kg00qf 5246 7 colon colon NN cord-022526-j9kg00qf 5246 8 is be VBZ cord-022526-j9kg00qf 5246 9 a a DT cord-022526-j9kg00qf 5246 10 rare rare JJ cord-022526-j9kg00qf 5246 11 congenital congenital JJ cord-022526-j9kg00qf 5246 12 abnormality abnormality NN cord-022526-j9kg00qf 5246 13 in in IN cord-022526-j9kg00qf 5246 14 horses horse NNS cord-022526-j9kg00qf 5246 15 . . . cord-022526-j9kg00qf 5247 1 The the DT cord-022526-j9kg00qf 5247 2 heritability heritability NN cord-022526-j9kg00qf 5247 3 and and CC cord-022526-j9kg00qf 5247 4 causes cause NNS cord-022526-j9kg00qf 5247 5 of of IN cord-022526-j9kg00qf 5247 6 the the DT cord-022526-j9kg00qf 5247 7 condition condition NN cord-022526-j9kg00qf 5247 8 are be VBP cord-022526-j9kg00qf 5247 9 unknown unknown JJ cord-022526-j9kg00qf 5247 10 . . . cord-022526-j9kg00qf 5248 1 One one CD cord-022526-j9kg00qf 5248 2 potential potential JJ cord-022526-j9kg00qf 5248 3 mechanism mechanism NN cord-022526-j9kg00qf 5248 4 for for IN cord-022526-j9kg00qf 5248 5 development development NN cord-022526-j9kg00qf 5248 6 of of IN cord-022526-j9kg00qf 5248 7 the the DT cord-022526-j9kg00qf 5248 8 lesion lesion NN cord-022526-j9kg00qf 5248 9 is be VBZ cord-022526-j9kg00qf 5248 10 intestinal intestinal JJ cord-022526-j9kg00qf 5248 11 ischemia ischemia NN cord-022526-j9kg00qf 5248 12 during during IN cord-022526-j9kg00qf 5248 13 fetal fetal JJ cord-022526-j9kg00qf 5248 14 life life NN cord-022526-j9kg00qf 5248 15 , , , cord-022526-j9kg00qf 5248 16 which which WDT cord-022526-j9kg00qf 5248 17 results result VBZ cord-022526-j9kg00qf 5248 18 in in IN cord-022526-j9kg00qf 5248 19 necrosis necrosis NN cord-022526-j9kg00qf 5248 20 of of IN cord-022526-j9kg00qf 5248 21 a a DT cord-022526-j9kg00qf 5248 22 segment segment NN cord-022526-j9kg00qf 5248 23 of of IN cord-022526-j9kg00qf 5248 24 intestine intestine NN cord-022526-j9kg00qf 5248 25 . . . cord-022526-j9kg00qf 5249 1 Clinical clinical JJ cord-022526-j9kg00qf 5249 2 signs sign NNS cord-022526-j9kg00qf 5249 3 include include VBP cord-022526-j9kg00qf 5249 4 a a DT cord-022526-j9kg00qf 5249 5 failure failure NN cord-022526-j9kg00qf 5249 6 to to TO cord-022526-j9kg00qf 5249 7 pass pass VB cord-022526-j9kg00qf 5249 8 meconium meconium NN cord-022526-j9kg00qf 5249 9 and and CC cord-022526-j9kg00qf 5249 10 colic colic NN cord-022526-j9kg00qf 5249 11 within within IN cord-022526-j9kg00qf 5249 12 the the DT cord-022526-j9kg00qf 5249 13 first first JJ cord-022526-j9kg00qf 5249 14 12 12 CD cord-022526-j9kg00qf 5249 15 to to TO cord-022526-j9kg00qf 5249 16 24 24 CD cord-022526-j9kg00qf 5249 17 hours hour NNS cord-022526-j9kg00qf 5249 18 of of IN cord-022526-j9kg00qf 5249 19 life life NN cord-022526-j9kg00qf 5249 20 . . . cord-022526-j9kg00qf 5250 1 Secondary secondary JJ cord-022526-j9kg00qf 5250 2 abdominal abdominal JJ cord-022526-j9kg00qf 5250 3 distention distention NN cord-022526-j9kg00qf 5250 4 results result NNS cord-022526-j9kg00qf 5250 5 from from IN cord-022526-j9kg00qf 5250 6 complete complete JJ cord-022526-j9kg00qf 5250 7 intestinal intestinal JJ cord-022526-j9kg00qf 5250 8 obstruction obstruction NN cord-022526-j9kg00qf 5250 9 , , , cord-022526-j9kg00qf 5250 10 and and CC cord-022526-j9kg00qf 5250 11 abdominal abdominal JJ cord-022526-j9kg00qf 5250 12 radiographs radiograph NNS cord-022526-j9kg00qf 5250 13 may may MD cord-022526-j9kg00qf 5250 14 reveal reveal VB cord-022526-j9kg00qf 5250 15 gas gas NN cord-022526-j9kg00qf 5250 16 - - HYPH cord-022526-j9kg00qf 5250 17 distended distend VBN cord-022526-j9kg00qf 5250 18 colon colon NN cord-022526-j9kg00qf 5250 19 . . . cord-022526-j9kg00qf 5251 1 One one PRP cord-022526-j9kg00qf 5251 2 makes make VBZ cord-022526-j9kg00qf 5251 3 the the DT cord-022526-j9kg00qf 5251 4 diagnosis diagnosis NN cord-022526-j9kg00qf 5251 5 at at IN cord-022526-j9kg00qf 5251 6 surgery surgery NN cord-022526-j9kg00qf 5251 7 . . . cord-022526-j9kg00qf 5252 1 Any any DT cord-022526-j9kg00qf 5252 2 portion portion NN cord-022526-j9kg00qf 5252 3 of of IN cord-022526-j9kg00qf 5252 4 the the DT cord-022526-j9kg00qf 5252 5 colon colon NN cord-022526-j9kg00qf 5252 6 may may MD cord-022526-j9kg00qf 5252 7 be be VB cord-022526-j9kg00qf 5252 8 absent absent JJ cord-022526-j9kg00qf 5252 9 , , , cord-022526-j9kg00qf 5252 10 but but CC cord-022526-j9kg00qf 5252 11 the the DT cord-022526-j9kg00qf 5252 12 distal distal JJ cord-022526-j9kg00qf 5252 13 segment segment NN cord-022526-j9kg00qf 5252 14 of of IN cord-022526-j9kg00qf 5252 15 the the DT cord-022526-j9kg00qf 5252 16 large large JJ cord-022526-j9kg00qf 5252 17 colon colon NN cord-022526-j9kg00qf 5252 18 or or CC cord-022526-j9kg00qf 5252 19 the the DT cord-022526-j9kg00qf 5252 20 proximal proximal JJ cord-022526-j9kg00qf 5252 21 small small JJ cord-022526-j9kg00qf 5252 22 colon colon NN cord-022526-j9kg00qf 5252 23 usually usually RB cord-022526-j9kg00qf 5252 24 is be VBZ cord-022526-j9kg00qf 5252 25 affected affect VBN cord-022526-j9kg00qf 5252 26 most most RBS cord-022526-j9kg00qf 5252 27 severely severely RB cord-022526-j9kg00qf 5252 28 . . . cord-022526-j9kg00qf 5253 1 If if IN cord-022526-j9kg00qf 5253 2 sufficient sufficient JJ cord-022526-j9kg00qf 5253 3 tissue tissue NN cord-022526-j9kg00qf 5253 4 is be VBZ cord-022526-j9kg00qf 5253 5 present present JJ cord-022526-j9kg00qf 5253 6 , , , cord-022526-j9kg00qf 5253 7 one one PRP cord-022526-j9kg00qf 5253 8 may may MD cord-022526-j9kg00qf 5253 9 attempt attempt VB cord-022526-j9kg00qf 5253 10 anastomosis anastomosis NN cord-022526-j9kg00qf 5253 11 to to IN cord-022526-j9kg00qf 5253 12 the the DT cord-022526-j9kg00qf 5253 13 proximal proximal JJ cord-022526-j9kg00qf 5253 14 blind blind JJ cord-022526-j9kg00qf 5253 15 end end NN cord-022526-j9kg00qf 5253 16 of of IN cord-022526-j9kg00qf 5253 17 the the DT cord-022526-j9kg00qf 5253 18 colon colon NN cord-022526-j9kg00qf 5253 19 . . . cord-022526-j9kg00qf 5254 1 117 117 CD cord-022526-j9kg00qf 5255 1 The the DT cord-022526-j9kg00qf 5255 2 prognosis prognosis NN cord-022526-j9kg00qf 5255 3 depends depend VBZ cord-022526-j9kg00qf 5255 4 on on IN cord-022526-j9kg00qf 5255 5 which which WDT cord-022526-j9kg00qf 5255 6 segment segment NN cord-022526-j9kg00qf 5255 7 of of IN cord-022526-j9kg00qf 5255 8 the the DT cord-022526-j9kg00qf 5255 9 colon colon NN cord-022526-j9kg00qf 5255 10 is be VBZ cord-022526-j9kg00qf 5255 11 absent absent JJ cord-022526-j9kg00qf 5255 12 but but CC cord-022526-j9kg00qf 5255 13 is be VBZ cord-022526-j9kg00qf 5255 14 usually usually RB cord-022526-j9kg00qf 5255 15 poor poor JJ cord-022526-j9kg00qf 5255 16 because because IN cord-022526-j9kg00qf 5255 17 of of IN cord-022526-j9kg00qf 5255 18 an an DT cord-022526-j9kg00qf 5255 19 absence absence NN cord-022526-j9kg00qf 5255 20 of of IN cord-022526-j9kg00qf 5255 21 distal distal JJ cord-022526-j9kg00qf 5255 22 colon colon NN cord-022526-j9kg00qf 5255 23 . . . cord-022526-j9kg00qf 5256 1 Neoplasia neoplasia NN cord-022526-j9kg00qf 5256 2 in in IN cord-022526-j9kg00qf 5256 3 the the DT cord-022526-j9kg00qf 5256 4 alimentary alimentary JJ cord-022526-j9kg00qf 5256 5 tract tract NN cord-022526-j9kg00qf 5256 6 of of IN cord-022526-j9kg00qf 5256 7 the the DT cord-022526-j9kg00qf 5256 8 horse horse NN cord-022526-j9kg00qf 5256 9 is be VBZ cord-022526-j9kg00qf 5256 10 uncommon uncommon JJ cord-022526-j9kg00qf 5256 11 . . . cord-022526-j9kg00qf 5257 1 1 1 LS cord-022526-j9kg00qf 5258 1 Primary primary JJ cord-022526-j9kg00qf 5258 2 and and CC cord-022526-j9kg00qf 5258 3 metastatic metastatic JJ cord-022526-j9kg00qf 5258 4 neoplasia neoplasia NN cord-022526-j9kg00qf 5258 5 can can MD cord-022526-j9kg00qf 5258 6 affect affect VB cord-022526-j9kg00qf 5258 7 multiple multiple JJ cord-022526-j9kg00qf 5258 8 locations location NNS cord-022526-j9kg00qf 5258 9 within within IN cord-022526-j9kg00qf 5258 10 the the DT cord-022526-j9kg00qf 5258 11 oral oral JJ cord-022526-j9kg00qf 5258 12 cavity cavity NN cord-022526-j9kg00qf 5258 13 and and CC cord-022526-j9kg00qf 5258 14 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5258 15 tract tract NN cord-022526-j9kg00qf 5258 16 ( ( -LRB- cord-022526-j9kg00qf 5258 17 Boxes box NNS cord-022526-j9kg00qf 5258 18 13.16 13.16 CD cord-022526-j9kg00qf 5258 19 - - SYM cord-022526-j9kg00qf 5258 20 1 1 CD cord-022526-j9kg00qf 5258 21 and and CC cord-022526-j9kg00qf 5258 22 13.16 13.16 CD cord-022526-j9kg00qf 5258 23 - - SYM cord-022526-j9kg00qf 5258 24 2 2 CD cord-022526-j9kg00qf 5258 25 ) ) -RRB- cord-022526-j9kg00qf 5258 26 . . . cord-022526-j9kg00qf 5259 1 Neoplasia neoplasia NN cord-022526-j9kg00qf 5259 2 is be VBZ cord-022526-j9kg00qf 5259 3 not not RB cord-022526-j9kg00qf 5259 4 limited limit VBN cord-022526-j9kg00qf 5259 5 to to IN cord-022526-j9kg00qf 5259 6 older old JJR cord-022526-j9kg00qf 5259 7 horses horse NNS cord-022526-j9kg00qf 5259 8 . . . cord-022526-j9kg00qf 5260 1 The the DT cord-022526-j9kg00qf 5260 2 average average JJ cord-022526-j9kg00qf 5260 3 age age NN cord-022526-j9kg00qf 5260 4 of of IN cord-022526-j9kg00qf 5260 5 horses horse NNS cord-022526-j9kg00qf 5260 6 with with IN cord-022526-j9kg00qf 5260 7 squamous squamous JJ cord-022526-j9kg00qf 5260 8 cell cell NN cord-022526-j9kg00qf 5260 9 carcinoma carcinoma NN cord-022526-j9kg00qf 5260 10 is be VBZ cord-022526-j9kg00qf 5260 11 8.6 8.6 CD cord-022526-j9kg00qf 5260 12 to to IN cord-022526-j9kg00qf 5260 13 14.6 14.6 CD cord-022526-j9kg00qf 5260 14 years year NNS cord-022526-j9kg00qf 5260 15 . . . cord-022526-j9kg00qf 5261 1 2 2 LS cord-022526-j9kg00qf 5261 2 , , , cord-022526-j9kg00qf 5261 3 3 3 CD cord-022526-j9kg00qf 5262 1 The the DT cord-022526-j9kg00qf 5262 2 alimentary alimentary JJ cord-022526-j9kg00qf 5262 3 form form NN cord-022526-j9kg00qf 5262 4 of of IN cord-022526-j9kg00qf 5262 5 lymphoma lymphoma NN cord-022526-j9kg00qf 5262 6 occurs occur VBZ cord-022526-j9kg00qf 5262 7 most most RBS cord-022526-j9kg00qf 5262 8 commonly commonly RB cord-022526-j9kg00qf 5262 9 in in IN cord-022526-j9kg00qf 5262 10 horses horse NNS cord-022526-j9kg00qf 5262 11 less less JJR cord-022526-j9kg00qf 5262 12 than than IN cord-022526-j9kg00qf 5262 13 5 5 CD cord-022526-j9kg00qf 5262 14 years year NNS cord-022526-j9kg00qf 5262 15 of of IN cord-022526-j9kg00qf 5262 16 age age NN cord-022526-j9kg00qf 5262 17 . . . cord-022526-j9kg00qf 5263 1 4 4 LS cord-022526-j9kg00qf 5263 2 Identification identification NN cord-022526-j9kg00qf 5263 3 of of IN cord-022526-j9kg00qf 5263 4 benign benign JJ cord-022526-j9kg00qf 5263 5 versus versus IN cord-022526-j9kg00qf 5263 6 malignant malignant JJ cord-022526-j9kg00qf 5263 7 tumors tumor NNS cord-022526-j9kg00qf 5263 8 is be VBZ cord-022526-j9kg00qf 5263 9 imperative imperative JJ cord-022526-j9kg00qf 5263 10 to to TO cord-022526-j9kg00qf 5263 11 justify justify VB cord-022526-j9kg00qf 5263 12 treatment treatment NN cord-022526-j9kg00qf 5263 13 and and CC cord-022526-j9kg00qf 5263 14 predict predict VB cord-022526-j9kg00qf 5263 15 survival survival NN cord-022526-j9kg00qf 5263 16 . . . cord-022526-j9kg00qf 5264 1 Clinical clinical JJ cord-022526-j9kg00qf 5264 2 signs sign NNS cord-022526-j9kg00qf 5264 3 associated associate VBN cord-022526-j9kg00qf 5264 4 with with IN cord-022526-j9kg00qf 5264 5 alimentary alimentary JJ cord-022526-j9kg00qf 5264 6 neoplasia neoplasia NNS cord-022526-j9kg00qf 5264 7 are be VBP cord-022526-j9kg00qf 5264 8 related relate VBN cord-022526-j9kg00qf 5264 9 to to IN cord-022526-j9kg00qf 5264 10 the the DT cord-022526-j9kg00qf 5264 11 tumor tumor NN cord-022526-j9kg00qf 5264 12 location location NN cord-022526-j9kg00qf 5264 13 . . . cord-022526-j9kg00qf 5265 1 Clinical clinical JJ cord-022526-j9kg00qf 5265 2 signs sign NNS cord-022526-j9kg00qf 5265 3 of of IN cord-022526-j9kg00qf 5265 4 oral oral JJ cord-022526-j9kg00qf 5265 5 neoplasia neoplasia NN cord-022526-j9kg00qf 5265 6 can can MD cord-022526-j9kg00qf 5265 7 include include VB cord-022526-j9kg00qf 5265 8 enlargement enlargement NN cord-022526-j9kg00qf 5265 9 or or CC cord-022526-j9kg00qf 5265 10 ulceration ulceration NN cord-022526-j9kg00qf 5265 11 of of IN cord-022526-j9kg00qf 5265 12 the the DT cord-022526-j9kg00qf 5265 13 mandible mandible NN cord-022526-j9kg00qf 5265 14 or or CC cord-022526-j9kg00qf 5265 15 maxilla maxilla NN cord-022526-j9kg00qf 5265 16 . . . cord-022526-j9kg00qf 5266 1 48 48 CD cord-022526-j9kg00qf 5266 2 Neoplasia neoplasia NN cord-022526-j9kg00qf 5266 3 of of IN cord-022526-j9kg00qf 5266 4 the the DT cord-022526-j9kg00qf 5266 5 tongue tongue NN cord-022526-j9kg00qf 5266 6 results result NNS cord-022526-j9kg00qf 5266 7 in in IN cord-022526-j9kg00qf 5266 8 weight weight NN cord-022526-j9kg00qf 5266 9 loss loss NN cord-022526-j9kg00qf 5266 10 , , , cord-022526-j9kg00qf 5266 11 quidding quidding NN cord-022526-j9kg00qf 5266 12 , , , cord-022526-j9kg00qf 5266 13 prepharyngeal prepharyngeal NN cord-022526-j9kg00qf 5266 14 dysphagia dysphagia NN cord-022526-j9kg00qf 5266 15 , , , cord-022526-j9kg00qf 5266 16 halitosis halitosis NN cord-022526-j9kg00qf 5266 17 , , , cord-022526-j9kg00qf 5266 18 and and CC cord-022526-j9kg00qf 5266 19 nasal nasal NN cord-022526-j9kg00qf 5266 20 discharge discharge NN cord-022526-j9kg00qf 5266 21 containing contain VBG cord-022526-j9kg00qf 5266 22 feed feed NN cord-022526-j9kg00qf 5266 23 material material NN cord-022526-j9kg00qf 5266 24 if if IN cord-022526-j9kg00qf 5266 25 the the DT cord-022526-j9kg00qf 5266 26 oropharynx oropharynx NN cord-022526-j9kg00qf 5266 27 is be VBZ cord-022526-j9kg00qf 5266 28 involved involve VBN cord-022526-j9kg00qf 5266 29 . . . cord-022526-j9kg00qf 5267 1 [ [ -LRB- cord-022526-j9kg00qf 5267 2 6 6 CD cord-022526-j9kg00qf 5267 3 ] ] -RRB- cord-022526-j9kg00qf 5267 4 [ [ -LRB- cord-022526-j9kg00qf 5267 5 7 7 CD cord-022526-j9kg00qf 5267 6 ] ] -RRB- cord-022526-j9kg00qf 5267 7 [ [ -LRB- cord-022526-j9kg00qf 5267 8 8 8 CD cord-022526-j9kg00qf 5267 9 ] ] -RRB- cord-022526-j9kg00qf 5268 1 Tumors tumor NNS cord-022526-j9kg00qf 5268 2 of of IN cord-022526-j9kg00qf 5268 3 the the DT cord-022526-j9kg00qf 5268 4 esophagus esophagus NN cord-022526-j9kg00qf 5268 5 cause cause NN cord-022526-j9kg00qf 5268 6 signs sign NNS cord-022526-j9kg00qf 5268 7 typical typical JJ cord-022526-j9kg00qf 5268 8 of of IN cord-022526-j9kg00qf 5268 9 esophageal esophageal JJ cord-022526-j9kg00qf 5268 10 dysphagia dysphagia NN cord-022526-j9kg00qf 5268 11 , , , cord-022526-j9kg00qf 5268 12 ptyalism ptyalism NN cord-022526-j9kg00qf 5268 13 , , , cord-022526-j9kg00qf 5268 14 choke choke VB cord-022526-j9kg00qf 5268 15 , , , cord-022526-j9kg00qf 5268 16 intermittent intermittent JJ cord-022526-j9kg00qf 5268 17 colic colic NN cord-022526-j9kg00qf 5268 18 , , , cord-022526-j9kg00qf 5268 19 fever fever NN cord-022526-j9kg00qf 5268 20 , , , cord-022526-j9kg00qf 5268 21 weight weight NN cord-022526-j9kg00qf 5268 22 loss loss NN cord-022526-j9kg00qf 5268 23 , , , cord-022526-j9kg00qf 5268 24 and and CC cord-022526-j9kg00qf 5268 25 halitosis halitosis NN cord-022526-j9kg00qf 5268 26 . . . cord-022526-j9kg00qf 5269 1 10 10 CD cord-022526-j9kg00qf 5269 2 , , , cord-022526-j9kg00qf 5269 3 49 49 CD cord-022526-j9kg00qf 5269 4 , , , cord-022526-j9kg00qf 5269 5 50 50 CD cord-022526-j9kg00qf 5269 6 Gastric gastric JJ cord-022526-j9kg00qf 5269 7 neoplasia neoplasia NNS cord-022526-j9kg00qf 5269 8 can can MD cord-022526-j9kg00qf 5269 9 be be VB cord-022526-j9kg00qf 5269 10 associated associate VBN cord-022526-j9kg00qf 5269 11 with with IN cord-022526-j9kg00qf 5269 12 abnormal abnormal JJ cord-022526-j9kg00qf 5269 13 chewing chewing NN cord-022526-j9kg00qf 5269 14 and and CC cord-022526-j9kg00qf 5269 15 swallowing swallow VBG cord-022526-j9kg00qf 5269 16 behavior behavior NN cord-022526-j9kg00qf 5269 17 , , , cord-022526-j9kg00qf 5269 18 anorexia anorexia NN cord-022526-j9kg00qf 5269 19 , , , cord-022526-j9kg00qf 5269 20 weight weight NN cord-022526-j9kg00qf 5269 21 loss loss NN cord-022526-j9kg00qf 5269 22 , , , cord-022526-j9kg00qf 5269 23 chronic chronic JJ cord-022526-j9kg00qf 5269 24 intermittent intermittent JJ cord-022526-j9kg00qf 5269 25 colic colic NN cord-022526-j9kg00qf 5269 26 , , , cord-022526-j9kg00qf 5269 27 abdominal abdominal JJ cord-022526-j9kg00qf 5269 28 distention distention NN cord-022526-j9kg00qf 5269 29 , , , cord-022526-j9kg00qf 5269 30 and and CC cord-022526-j9kg00qf 5269 31 intermittent intermittent JJ cord-022526-j9kg00qf 5269 32 fever fever NN cord-022526-j9kg00qf 5269 33 . . . cord-022526-j9kg00qf 5270 1 16 16 CD cord-022526-j9kg00qf 5270 2 Abdominal abdominal JJ cord-022526-j9kg00qf 5270 3 neoplasia neoplasia NN cord-022526-j9kg00qf 5270 4 has have VBZ cord-022526-j9kg00qf 5270 5 been be VBN cord-022526-j9kg00qf 5270 6 implicated implicate VBN cord-022526-j9kg00qf 5270 7 in in IN cord-022526-j9kg00qf 5270 8 4 4 CD cord-022526-j9kg00qf 5270 9 % % NN cord-022526-j9kg00qf 5270 10 of of IN cord-022526-j9kg00qf 5270 11 horses horse NNS cord-022526-j9kg00qf 5270 12 with with IN cord-022526-j9kg00qf 5270 13 intermittent intermittent JJ cord-022526-j9kg00qf 5270 14 or or CC cord-022526-j9kg00qf 5270 15 chronic chronic JJ cord-022526-j9kg00qf 5270 16 colic colic NN cord-022526-j9kg00qf 5270 17 . . . cord-022526-j9kg00qf 5271 1 51 51 CD cord-022526-j9kg00qf 5271 2 , , , cord-022526-j9kg00qf 5271 3 52 52 CD cord-022526-j9kg00qf 5271 4 Altered alter VBN cord-022526-j9kg00qf 5271 5 stool stool NN cord-022526-j9kg00qf 5271 6 character character NN cord-022526-j9kg00qf 5271 7 , , , cord-022526-j9kg00qf 5271 8 weight weight NN cord-022526-j9kg00qf 5271 9 loss loss NN cord-022526-j9kg00qf 5271 10 , , , cord-022526-j9kg00qf 5271 11 ventral ventral JJ cord-022526-j9kg00qf 5271 12 edema edema NN cord-022526-j9kg00qf 5271 13 , , , cord-022526-j9kg00qf 5271 14 and and CC cord-022526-j9kg00qf 5271 15 recurrent recurrent JJ cord-022526-j9kg00qf 5271 16 fever fever NN cord-022526-j9kg00qf 5271 17 have have VBP cord-022526-j9kg00qf 5271 18 been be VBN cord-022526-j9kg00qf 5271 19 associated associate VBN cord-022526-j9kg00qf 5271 20 with with IN cord-022526-j9kg00qf 5271 21 intestinal intestinal JJ cord-022526-j9kg00qf 5271 22 neoplasia neoplasia NN cord-022526-j9kg00qf 5271 23 . . . cord-022526-j9kg00qf 5272 1 4 4 CD cord-022526-j9kg00qf 5272 2 Acute acute JJ cord-022526-j9kg00qf 5272 3 signs sign NNS cord-022526-j9kg00qf 5272 4 of of IN cord-022526-j9kg00qf 5272 5 abdominal abdominal JJ cord-022526-j9kg00qf 5272 6 discomfort discomfort NN cord-022526-j9kg00qf 5272 7 can can MD cord-022526-j9kg00qf 5272 8 occur occur VB cord-022526-j9kg00qf 5272 9 in in IN cord-022526-j9kg00qf 5272 10 intestinal intestinal JJ cord-022526-j9kg00qf 5272 11 obstructions obstruction NNS cord-022526-j9kg00qf 5272 12 from from IN cord-022526-j9kg00qf 5272 13 malignant malignant JJ cord-022526-j9kg00qf 5272 14 and and CC cord-022526-j9kg00qf 5272 15 benign benign JJ cord-022526-j9kg00qf 5272 16 neoplastic neoplastic JJ cord-022526-j9kg00qf 5272 17 disease disease NN cord-022526-j9kg00qf 5272 18 . . . cord-022526-j9kg00qf 5273 1 Paraneoplastic paraneoplastic JJ cord-022526-j9kg00qf 5273 2 syndromes syndrome NNS cord-022526-j9kg00qf 5273 3 may may MD cord-022526-j9kg00qf 5273 4 occur occur VB cord-022526-j9kg00qf 5273 5 in in IN cord-022526-j9kg00qf 5273 6 the the DT cord-022526-j9kg00qf 5273 7 horse horse NN cord-022526-j9kg00qf 5273 8 . . . cord-022526-j9kg00qf 5274 1 The the DT cord-022526-j9kg00qf 5274 2 most most RBS cord-022526-j9kg00qf 5274 3 common common JJ cord-022526-j9kg00qf 5274 4 syndromes syndrome NNS cord-022526-j9kg00qf 5274 5 are be VBP cord-022526-j9kg00qf 5274 6 cancer cancer NN cord-022526-j9kg00qf 5274 7 cachexia cachexia NN cord-022526-j9kg00qf 5274 8 , , , cord-022526-j9kg00qf 5274 9 ectopic ectopic JJ cord-022526-j9kg00qf 5274 10 hormone hormone NN cord-022526-j9kg00qf 5274 11 production production NN cord-022526-j9kg00qf 5274 12 , , , cord-022526-j9kg00qf 5274 13 anemia anemia NN cord-022526-j9kg00qf 5274 14 , , , cord-022526-j9kg00qf 5274 15 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 5274 16 , , , cord-022526-j9kg00qf 5274 17 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 5274 18 , , , cord-022526-j9kg00qf 5274 19 hypergammaglobulinemia hypergammaglobulinemia NN cord-022526-j9kg00qf 5274 20 , , , cord-022526-j9kg00qf 5274 21 fever fever NN cord-022526-j9kg00qf 5274 22 , , , cord-022526-j9kg00qf 5274 23 and and CC cord-022526-j9kg00qf 5274 24 neurologic neurologic JJ cord-022526-j9kg00qf 5274 25 abnormalities abnormality NNS cord-022526-j9kg00qf 5274 26 . . . cord-022526-j9kg00qf 5275 1 53 53 CD cord-022526-j9kg00qf 5275 2 Horses horse NNS cord-022526-j9kg00qf 5275 3 with with IN cord-022526-j9kg00qf 5275 4 cancer cancer NN cord-022526-j9kg00qf 5275 5 cachexia cachexia NN cord-022526-j9kg00qf 5275 6 have have VBP cord-022526-j9kg00qf 5275 7 profound profound JJ cord-022526-j9kg00qf 5275 8 weight weight NN cord-022526-j9kg00qf 5275 9 loss loss NN cord-022526-j9kg00qf 5275 10 despite despite IN cord-022526-j9kg00qf 5275 11 adequate adequate JJ cord-022526-j9kg00qf 5275 12 consumption consumption NN cord-022526-j9kg00qf 5275 13 of of IN cord-022526-j9kg00qf 5275 14 calories calorie NNS cord-022526-j9kg00qf 5275 15 . . . cord-022526-j9kg00qf 5276 1 Diagnosis diagnosis NN cord-022526-j9kg00qf 5276 2 of of IN cord-022526-j9kg00qf 5276 3 alimentary alimentary JJ cord-022526-j9kg00qf 5276 4 neoplasia neoplasia NN cord-022526-j9kg00qf 5276 5 can can MD cord-022526-j9kg00qf 5276 6 be be VB cord-022526-j9kg00qf 5276 7 challenging challenging JJ cord-022526-j9kg00qf 5276 8 . . . cord-022526-j9kg00qf 5277 1 Data datum NNS cord-022526-j9kg00qf 5277 2 collected collect VBN cord-022526-j9kg00qf 5277 3 from from IN cord-022526-j9kg00qf 5277 4 a a DT cord-022526-j9kg00qf 5277 5 complete complete JJ cord-022526-j9kg00qf 5277 6 blood blood NN cord-022526-j9kg00qf 5277 7 count count NN cord-022526-j9kg00qf 5277 8 , , , cord-022526-j9kg00qf 5277 9 biochemistry biochemistry NN cord-022526-j9kg00qf 5277 10 panel panel NN cord-022526-j9kg00qf 5277 11 , , , cord-022526-j9kg00qf 5277 12 and and CC cord-022526-j9kg00qf 5277 13 urinalysis urinalysis NN cord-022526-j9kg00qf 5277 14 may may MD cord-022526-j9kg00qf 5277 15 support support VB cord-022526-j9kg00qf 5277 16 the the DT cord-022526-j9kg00qf 5277 17 diagnosis diagnosis NN cord-022526-j9kg00qf 5277 18 of of IN cord-022526-j9kg00qf 5277 19 neoplasia neoplasia NN cord-022526-j9kg00qf 5277 20 but but CC cord-022526-j9kg00qf 5277 21 rarely rarely RB cord-022526-j9kg00qf 5277 22 confirms confirm VBZ cord-022526-j9kg00qf 5277 23 it -PRON- PRP cord-022526-j9kg00qf 5277 24 . . . cord-022526-j9kg00qf 5278 1 Normocytic normocytic JJ cord-022526-j9kg00qf 5278 2 normochromic normochromic JJ cord-022526-j9kg00qf 5278 3 anemia anemia NN cord-022526-j9kg00qf 5278 4 indicates indicate VBZ cord-022526-j9kg00qf 5278 5 chronic chronic JJ cord-022526-j9kg00qf 5278 6 disease disease NN cord-022526-j9kg00qf 5278 7 and and CC cord-022526-j9kg00qf 5278 8 is be VBZ cord-022526-j9kg00qf 5278 9 the the DT cord-022526-j9kg00qf 5278 10 most most RBS cord-022526-j9kg00qf 5278 11 likely likely JJ cord-022526-j9kg00qf 5278 12 cause cause NN cord-022526-j9kg00qf 5278 13 of of IN cord-022526-j9kg00qf 5278 14 anemia anemia NN cord-022526-j9kg00qf 5278 15 associated associate VBN cord-022526-j9kg00qf 5278 16 with with IN cord-022526-j9kg00qf 5278 17 neoplasia neoplasia NN cord-022526-j9kg00qf 5278 18 . . . cord-022526-j9kg00qf 5279 1 Blood blood NN cord-022526-j9kg00qf 5279 2 loss loss NN cord-022526-j9kg00qf 5279 3 anemia anemia NN cord-022526-j9kg00qf 5279 4 ( ( -LRB- cord-022526-j9kg00qf 5279 5 via via IN cord-022526-j9kg00qf 5279 6 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5279 7 tract tract NN cord-022526-j9kg00qf 5279 8 ) ) -RRB- cord-022526-j9kg00qf 5279 9 and and CC cord-022526-j9kg00qf 5279 10 immune immune NN cord-022526-j9kg00qf 5279 11 - - HYPH cord-022526-j9kg00qf 5279 12 mediated mediate VBN cord-022526-j9kg00qf 5279 13 hemolytic hemolytic JJ cord-022526-j9kg00qf 5279 14 anemia anemia NN cord-022526-j9kg00qf 5279 15 ( ( -LRB- cord-022526-j9kg00qf 5279 16 lymphoma lymphoma NN cord-022526-j9kg00qf 5279 17 ) ) -RRB- cord-022526-j9kg00qf 5279 18 54 54 CD cord-022526-j9kg00qf 5279 19 are be VBP cord-022526-j9kg00qf 5279 20 less less RBR cord-022526-j9kg00qf 5279 21 frequent frequent JJ cord-022526-j9kg00qf 5279 22 causes cause NNS cord-022526-j9kg00qf 5279 23 of of IN cord-022526-j9kg00qf 5279 24 anemia anemia NN cord-022526-j9kg00qf 5279 25 associated associate VBN cord-022526-j9kg00qf 5279 26 with with IN cord-022526-j9kg00qf 5279 27 abdominal abdominal JJ cord-022526-j9kg00qf 5279 28 neoplasia neoplasia NN cord-022526-j9kg00qf 5279 29 . . . cord-022526-j9kg00qf 5280 1 Peripheral peripheral JJ cord-022526-j9kg00qf 5280 2 eosinophilia eosinophilia NN cord-022526-j9kg00qf 5280 3 has have VBZ cord-022526-j9kg00qf 5280 4 been be VBN cord-022526-j9kg00qf 5280 5 reported report VBN cord-022526-j9kg00qf 5280 6 in in IN cord-022526-j9kg00qf 5280 7 association association NN cord-022526-j9kg00qf 5280 8 with with IN cord-022526-j9kg00qf 5280 9 multisystemic multisystemic NNP cord-022526-j9kg00qf 5280 10 eosinophilic eosinophilic NNP cord-022526-j9kg00qf 5280 11 , , , cord-022526-j9kg00qf 5280 12 epitheliotropic epitheliotropic NNP cord-022526-j9kg00qf 5280 13 disease disease NN cord-022526-j9kg00qf 5280 14 with with IN cord-022526-j9kg00qf 5280 15 lymphoma lymphoma NN cord-022526-j9kg00qf 5280 16 . . . cord-022526-j9kg00qf 5281 1 14 14 CD cord-022526-j9kg00qf 5282 1 Leukocytosis Leukocytosis NNP cord-022526-j9kg00qf 5282 2 and and CC cord-022526-j9kg00qf 5282 3 hyperfibrinogenemia hyperfibrinogenemia NN cord-022526-j9kg00qf 5282 4 are be VBP cord-022526-j9kg00qf 5282 5 common common JJ cord-022526-j9kg00qf 5282 6 findings finding NNS cord-022526-j9kg00qf 5282 7 . . . cord-022526-j9kg00qf 5283 1 Serum serum NN cord-022526-j9kg00qf 5283 2 chemistry chemistry NN cord-022526-j9kg00qf 5283 3 can can MD cord-022526-j9kg00qf 5283 4 confirm confirm VB cord-022526-j9kg00qf 5283 5 hypoalbuminemia hypoalbuminemia NN cord-022526-j9kg00qf 5283 6 caused cause VBN cord-022526-j9kg00qf 5283 7 by by IN cord-022526-j9kg00qf 5283 8 inflammation inflammation NN cord-022526-j9kg00qf 5283 9 of of IN cord-022526-j9kg00qf 5283 10 the the DT cord-022526-j9kg00qf 5283 11 bowel bowel NN cord-022526-j9kg00qf 5283 12 wall wall NN cord-022526-j9kg00qf 5283 13 . . . cord-022526-j9kg00qf 5284 1 Hyperglobulinemia Hyperglobulinemia NNP cord-022526-j9kg00qf 5284 2 can can MD cord-022526-j9kg00qf 5284 3 be be VB cord-022526-j9kg00qf 5284 4 characterized characterize VBN cord-022526-j9kg00qf 5284 5 with with IN cord-022526-j9kg00qf 5284 6 serum serum NN cord-022526-j9kg00qf 5284 7 electrophoresis electrophoresis NN cord-022526-j9kg00qf 5284 8 , , , cord-022526-j9kg00qf 5284 9 which which WDT cord-022526-j9kg00qf 5284 10 is be VBZ cord-022526-j9kg00qf 5284 11 nonspecific nonspecific JJ cord-022526-j9kg00qf 5284 12 and and CC cord-022526-j9kg00qf 5284 13 can can MD cord-022526-j9kg00qf 5284 14 reveal reveal VB cord-022526-j9kg00qf 5284 15 chronic chronic JJ cord-022526-j9kg00qf 5284 16 inflammation inflammation NN cord-022526-j9kg00qf 5284 17 . . . cord-022526-j9kg00qf 5285 1 A a DT cord-022526-j9kg00qf 5285 2 few few JJ cord-022526-j9kg00qf 5285 3 cases case NNS cord-022526-j9kg00qf 5285 4 of of IN cord-022526-j9kg00qf 5285 5 lymphoma lymphoma NN cord-022526-j9kg00qf 5285 6 have have VBP cord-022526-j9kg00qf 5285 7 been be VBN cord-022526-j9kg00qf 5285 8 identified identify VBN cord-022526-j9kg00qf 5285 9 with with IN cord-022526-j9kg00qf 5285 10 monoclonal monoclonal JJ cord-022526-j9kg00qf 5285 11 hypergammaglobulinemia hypergammaglobulinemia NN cord-022526-j9kg00qf 5285 12 . . . cord-022526-j9kg00qf 5286 1 55 55 CD cord-022526-j9kg00qf 5286 2 Ectopic ectopic JJ cord-022526-j9kg00qf 5286 3 hormone hormone NN cord-022526-j9kg00qf 5286 4 production production NN cord-022526-j9kg00qf 5286 5 may may MD cord-022526-j9kg00qf 5286 6 result result VB cord-022526-j9kg00qf 5286 7 in in IN cord-022526-j9kg00qf 5286 8 hypercalcemia hypercalcemia NN cord-022526-j9kg00qf 5286 9 ( ( -LRB- cord-022526-j9kg00qf 5286 10 calcium calcium NN cord-022526-j9kg00qf 5286 11 > > XX cord-022526-j9kg00qf 5286 12 14 14 CD cord-022526-j9kg00qf 5286 13 mg mg NNP cord-022526-j9kg00qf 5286 14 / / SYM cord-022526-j9kg00qf 5286 15 dl dl NNP cord-022526-j9kg00qf 5286 16 ) ) -RRB- cord-022526-j9kg00qf 5286 17 , , , cord-022526-j9kg00qf 5286 18 which which WDT cord-022526-j9kg00qf 5286 19 is be VBZ cord-022526-j9kg00qf 5286 20 associated associate VBN cord-022526-j9kg00qf 5286 21 with with IN cord-022526-j9kg00qf 5286 22 alimentary alimentary JJ cord-022526-j9kg00qf 5286 23 neoplasia neoplasia NN cord-022526-j9kg00qf 5286 24 such such JJ cord-022526-j9kg00qf 5286 25 as as IN cord-022526-j9kg00qf 5286 26 lymphoma lymphoma NN cord-022526-j9kg00qf 5286 27 , , , cord-022526-j9kg00qf 5286 28 multiple multiple JJ cord-022526-j9kg00qf 5286 29 myeloma myeloma NN cord-022526-j9kg00qf 5286 30 , , , cord-022526-j9kg00qf 5286 31 carcinomata carcinomata NN cord-022526-j9kg00qf 5286 32 , , , cord-022526-j9kg00qf 5286 33 and and CC cord-022526-j9kg00qf 5286 34 ameloblastoma ameloblastoma NN cord-022526-j9kg00qf 5286 35 . . . cord-022526-j9kg00qf 5287 1 2 2 LS cord-022526-j9kg00qf 5287 2 , , , cord-022526-j9kg00qf 5287 3 56 56 CD cord-022526-j9kg00qf 5287 4 Hypoglycemia hypoglycemia NN cord-022526-j9kg00qf 5287 5 ( ( -LRB- cord-022526-j9kg00qf 5287 6 blood blood NN cord-022526-j9kg00qf 5287 7 glucose glucose NN cord-022526-j9kg00qf 5288 1 < < XX cord-022526-j9kg00qf 5288 2 70 70 CD cord-022526-j9kg00qf 5288 3 mg mg NNP cord-022526-j9kg00qf 5288 4 / / SYM cord-022526-j9kg00qf 5288 5 dl dl NN cord-022526-j9kg00qf 5288 6 ) ) -RRB- cord-022526-j9kg00qf 5288 7 can can MD cord-022526-j9kg00qf 5288 8 occur occur VB cord-022526-j9kg00qf 5288 9 with with IN cord-022526-j9kg00qf 5288 10 neoplasia neoplasia NN cord-022526-j9kg00qf 5288 11 of of IN cord-022526-j9kg00qf 5288 12 the the DT cord-022526-j9kg00qf 5288 13 pancreas pancreas NN cord-022526-j9kg00qf 5288 14 or or CC cord-022526-j9kg00qf 5288 15 liver liver NN cord-022526-j9kg00qf 5288 16 . . . cord-022526-j9kg00qf 5289 1 2 2 CD cord-022526-j9kg00qf 5289 2 Rectal rectal JJ cord-022526-j9kg00qf 5289 3 examination examination NN cord-022526-j9kg00qf 5289 4 may may MD cord-022526-j9kg00qf 5289 5 detect detect VB cord-022526-j9kg00qf 5289 6 an an DT cord-022526-j9kg00qf 5289 7 abdominal abdominal JJ cord-022526-j9kg00qf 5289 8 mass mass NN cord-022526-j9kg00qf 5289 9 , , , cord-022526-j9kg00qf 5289 10 thickening thickening NN cord-022526-j9kg00qf 5289 11 of of IN cord-022526-j9kg00qf 5289 12 the the DT cord-022526-j9kg00qf 5289 13 intestinal intestinal JJ cord-022526-j9kg00qf 5289 14 wall wall NN cord-022526-j9kg00qf 5289 15 , , , cord-022526-j9kg00qf 5289 16 lymph lymph NN cord-022526-j9kg00qf 5289 17 node node NN cord-022526-j9kg00qf 5289 18 enlargement enlargement NN cord-022526-j9kg00qf 5289 19 , , , cord-022526-j9kg00qf 5289 20 or or CC cord-022526-j9kg00qf 5289 21 a a DT cord-022526-j9kg00qf 5289 22 gritty gritty JJ cord-022526-j9kg00qf 5289 23 texture texture NN cord-022526-j9kg00qf 5289 24 in in IN cord-022526-j9kg00qf 5289 25 horses horse NNS cord-022526-j9kg00qf 5289 26 with with IN cord-022526-j9kg00qf 5289 27 carcinomatosis carcinomatosis NN cord-022526-j9kg00qf 5289 28 . . . cord-022526-j9kg00qf 5290 1 2 2 CD cord-022526-j9kg00qf 5290 2 Rectal rectal JJ cord-022526-j9kg00qf 5290 3 biopsy biopsy NN cord-022526-j9kg00qf 5290 4 can can MD cord-022526-j9kg00qf 5290 5 reveal reveal VB cord-022526-j9kg00qf 5290 6 lymphoma lymphoma NN cord-022526-j9kg00qf 5290 7 in in IN cord-022526-j9kg00qf 5290 8 some some DT cord-022526-j9kg00qf 5290 9 cases case NNS cord-022526-j9kg00qf 5290 10 . . . cord-022526-j9kg00qf 5291 1 42 42 CD cord-022526-j9kg00qf 5291 2 Fecal fecal JJ cord-022526-j9kg00qf 5291 3 occult occult JJ cord-022526-j9kg00qf 5291 4 blood blood NN cord-022526-j9kg00qf 5291 5 test test NN cord-022526-j9kg00qf 5291 6 is be VBZ cord-022526-j9kg00qf 5291 7 nonspecific nonspecific JJ cord-022526-j9kg00qf 5291 8 for for IN cord-022526-j9kg00qf 5291 9 neoplastic neoplastic JJ cord-022526-j9kg00qf 5291 10 disease disease NN cord-022526-j9kg00qf 5291 11 but but CC cord-022526-j9kg00qf 5291 12 can can MD cord-022526-j9kg00qf 5291 13 reveal reveal VB cord-022526-j9kg00qf 5291 14 blood blood NN cord-022526-j9kg00qf 5291 15 loss loss NN cord-022526-j9kg00qf 5291 16 through through IN cord-022526-j9kg00qf 5291 17 the the DT cord-022526-j9kg00qf 5291 18 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5291 19 tract tract NN cord-022526-j9kg00qf 5291 20 . . . cord-022526-j9kg00qf 5292 1 Occasionally occasionally RB cord-022526-j9kg00qf 5292 2 , , , cord-022526-j9kg00qf 5292 3 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 5292 4 can can MD cord-022526-j9kg00qf 5292 5 identify identify VB cord-022526-j9kg00qf 5292 6 neoplasia neoplasia NN cord-022526-j9kg00qf 5292 7 if if IN cord-022526-j9kg00qf 5292 8 the the DT cord-022526-j9kg00qf 5292 9 tumor tumor NN cord-022526-j9kg00qf 5292 10 exfoliates exfoliate VBZ cord-022526-j9kg00qf 5292 11 cells cell NNS cord-022526-j9kg00qf 5292 12 into into IN cord-022526-j9kg00qf 5292 13 the the DT cord-022526-j9kg00qf 5292 14 abdomen abdomen NN cord-022526-j9kg00qf 5292 15 . . . cord-022526-j9kg00qf 5293 1 One one PRP cord-022526-j9kg00qf 5293 2 can can MD cord-022526-j9kg00qf 5293 3 diagnose diagnose VB cord-022526-j9kg00qf 5293 4 squamous squamous JJ cord-022526-j9kg00qf 5293 5 cell cell NN cord-022526-j9kg00qf 5293 6 carcinoma carcinoma NN cord-022526-j9kg00qf 5293 7 , , , cord-022526-j9kg00qf 5293 8 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5293 9 , , , cord-022526-j9kg00qf 5293 10 and and CC cord-022526-j9kg00qf 5293 11 mesothelioma mesothelioma NN cord-022526-j9kg00qf 5293 12 from from IN cord-022526-j9kg00qf 5293 13 peritoneal peritoneal JJ cord-022526-j9kg00qf 5293 14 fluid fluid NN cord-022526-j9kg00qf 5293 15 . . . cord-022526-j9kg00qf 5294 1 10 10 CD cord-022526-j9kg00qf 5294 2 , , , cord-022526-j9kg00qf 5294 3 45 45 CD cord-022526-j9kg00qf 5294 4 , , , cord-022526-j9kg00qf 5294 5 46 46 CD cord-022526-j9kg00qf 5294 6 , , , cord-022526-j9kg00qf 5294 7 57 57 CD cord-022526-j9kg00qf 5294 8 Characterization characterization NN cord-022526-j9kg00qf 5294 9 of of IN cord-022526-j9kg00qf 5294 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5294 11 fluid fluid NN cord-022526-j9kg00qf 5294 12 as as IN cord-022526-j9kg00qf 5294 13 an an DT cord-022526-j9kg00qf 5294 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 5294 15 exudate exudate NN cord-022526-j9kg00qf 5294 16 or or CC cord-022526-j9kg00qf 5294 17 modified modify VBN cord-022526-j9kg00qf 5294 18 transudate transudate NN cord-022526-j9kg00qf 5294 19 without without IN cord-022526-j9kg00qf 5294 20 any any DT cord-022526-j9kg00qf 5294 21 neoplastic neoplastic JJ cord-022526-j9kg00qf 5294 22 cells cell NNS cord-022526-j9kg00qf 5294 23 present present JJ cord-022526-j9kg00qf 5294 24 is be VBZ cord-022526-j9kg00qf 5294 25 common common JJ cord-022526-j9kg00qf 5294 26 . . . cord-022526-j9kg00qf 5295 1 Cytologic cytologic JJ cord-022526-j9kg00qf 5295 2 analysis analysis NN cord-022526-j9kg00qf 5295 3 of of IN cord-022526-j9kg00qf 5295 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5295 5 fluid fluid NN cord-022526-j9kg00qf 5295 6 samples sample NNS cord-022526-j9kg00qf 5295 7 collected collect VBN cord-022526-j9kg00qf 5295 8 by by IN cord-022526-j9kg00qf 5295 9 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 5295 10 accurately accurately RB cord-022526-j9kg00qf 5295 11 predicted predict VBD cord-022526-j9kg00qf 5295 12 the the DT cord-022526-j9kg00qf 5295 13 presence presence NN cord-022526-j9kg00qf 5295 14 of of IN cord-022526-j9kg00qf 5295 15 neoplasia neoplasia NN cord-022526-j9kg00qf 5295 16 in in IN cord-022526-j9kg00qf 5295 17 11 11 CD cord-022526-j9kg00qf 5295 18 of of IN cord-022526-j9kg00qf 5295 19 25 25 CD cord-022526-j9kg00qf 5295 20 cases case NNS cord-022526-j9kg00qf 5295 21 in in IN cord-022526-j9kg00qf 5295 22 one one CD cord-022526-j9kg00qf 5295 23 study study NN cord-022526-j9kg00qf 5295 24 . . . cord-022526-j9kg00qf 5296 1 58 58 CD cord-022526-j9kg00qf 5296 2 Cytologic Cytologic NNP cord-022526-j9kg00qf 5296 3 examination examination NN cord-022526-j9kg00qf 5296 4 of of IN cord-022526-j9kg00qf 5296 5 two two CD cord-022526-j9kg00qf 5296 6 or or CC cord-022526-j9kg00qf 5296 7 more more RBR cord-022526-j9kg00qf 5296 8 peritoneal peritoneal JJ cord-022526-j9kg00qf 5296 9 fluid fluid NN cord-022526-j9kg00qf 5296 10 samples sample NNS cord-022526-j9kg00qf 5296 11 increases increase VBZ cord-022526-j9kg00qf 5296 12 the the DT cord-022526-j9kg00qf 5296 13 sensitivity sensitivity NN cord-022526-j9kg00qf 5296 14 of of IN cord-022526-j9kg00qf 5296 15 this this DT cord-022526-j9kg00qf 5296 16 test test NN cord-022526-j9kg00qf 5296 17 for for IN cord-022526-j9kg00qf 5296 18 detecting detect VBG cord-022526-j9kg00qf 5296 19 abdominal abdominal JJ cord-022526-j9kg00qf 5296 20 neoplasia neoplasia NN cord-022526-j9kg00qf 5296 21 . . . cord-022526-j9kg00qf 5297 1 Measurement measurement NN cord-022526-j9kg00qf 5297 2 of of IN cord-022526-j9kg00qf 5297 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5297 4 fluid fluid JJ cord-022526-j9kg00qf 5297 5 glucose glucose NN cord-022526-j9kg00qf 5297 6 concentration concentration NN cord-022526-j9kg00qf 5297 7 and and CC cord-022526-j9kg00qf 5297 8 pH ph NN cord-022526-j9kg00qf 5297 9 is be VBZ cord-022526-j9kg00qf 5297 10 valuable valuable JJ cord-022526-j9kg00qf 5297 11 to to TO cord-022526-j9kg00qf 5297 12 differentiate differentiate VB cord-022526-j9kg00qf 5297 13 inflammation inflammation NN cord-022526-j9kg00qf 5297 14 in in IN cord-022526-j9kg00qf 5297 15 the the DT cord-022526-j9kg00qf 5297 16 peritoneum peritoneum NN cord-022526-j9kg00qf 5297 17 caused cause VBN cord-022526-j9kg00qf 5297 18 by by IN cord-022526-j9kg00qf 5297 19 neoplasia neoplasia NN cord-022526-j9kg00qf 5297 20 from from IN cord-022526-j9kg00qf 5297 21 bacterial bacterial JJ cord-022526-j9kg00qf 5297 22 peritonitis peritonitis NN cord-022526-j9kg00qf 5297 23 . . . cord-022526-j9kg00qf 5298 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5298 2 neoplasia neoplasia NN cord-022526-j9kg00qf 5298 3 typically typically RB cord-022526-j9kg00qf 5298 4 is be VBZ cord-022526-j9kg00qf 5298 5 associated associate VBN cord-022526-j9kg00qf 5298 6 with with IN cord-022526-j9kg00qf 5298 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 5298 8 glucose glucose NN cord-022526-j9kg00qf 5298 9 concentrations concentration NNS cord-022526-j9kg00qf 5298 10 similar similar JJ cord-022526-j9kg00qf 5298 11 to to IN cord-022526-j9kg00qf 5298 12 blood blood NN cord-022526-j9kg00qf 5298 13 and and CC cord-022526-j9kg00qf 5298 14 pH ph NN cord-022526-j9kg00qf 5298 15 higher high JJR cord-022526-j9kg00qf 5298 16 than than IN cord-022526-j9kg00qf 5298 17 7.3 7.3 CD cord-022526-j9kg00qf 5298 18 . . . cord-022526-j9kg00qf 5299 1 D d JJ cord-022526-j9kg00qf 5299 2 - - HYPH cord-022526-j9kg00qf 5299 3 xylose xylose NN cord-022526-j9kg00qf 5299 4 absorption absorption NN cord-022526-j9kg00qf 5299 5 tests test NNS cord-022526-j9kg00qf 5299 6 can can MD cord-022526-j9kg00qf 5299 7 reveal reveal VB cord-022526-j9kg00qf 5299 8 malabsorptive malabsorptive JJ cord-022526-j9kg00qf 5299 9 diseases disease NNS cord-022526-j9kg00qf 5299 10 that that WDT cord-022526-j9kg00qf 5299 11 include include VBP cord-022526-j9kg00qf 5299 12 lymphoma lymphoma NN cord-022526-j9kg00qf 5299 13 . . . cord-022526-j9kg00qf 5300 1 42 42 CD cord-022526-j9kg00qf 5300 2 , , , cord-022526-j9kg00qf 5300 3 59 59 CD cord-022526-j9kg00qf 5300 4 Immunoglobulin Immunoglobulin NNP cord-022526-j9kg00qf 5300 5 M M NNP cord-022526-j9kg00qf 5300 6 deficiency deficiency NN cord-022526-j9kg00qf 5300 7 is be VBZ cord-022526-j9kg00qf 5300 8 associated associate VBN cord-022526-j9kg00qf 5300 9 with with IN cord-022526-j9kg00qf 5300 10 lymphoma lymphoma NN cord-022526-j9kg00qf 5300 11 in in IN cord-022526-j9kg00qf 5300 12 some some DT cord-022526-j9kg00qf 5300 13 young young JJ cord-022526-j9kg00qf 5300 14 adult adult NN cord-022526-j9kg00qf 5300 15 horses horse NNS cord-022526-j9kg00qf 5300 16 , , , cord-022526-j9kg00qf 5300 17 but but CC cord-022526-j9kg00qf 5300 18 the the DT cord-022526-j9kg00qf 5300 19 prevalence prevalence NN cord-022526-j9kg00qf 5300 20 of of IN cord-022526-j9kg00qf 5300 21 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 5300 22 M m CD cord-022526-j9kg00qf 5300 23 deficiency deficiency NN cord-022526-j9kg00qf 5300 24 in in IN cord-022526-j9kg00qf 5300 25 horses horse NNS cord-022526-j9kg00qf 5300 26 with with IN cord-022526-j9kg00qf 5300 27 lymphoma lymphoma NN cord-022526-j9kg00qf 5300 28 and and CC cord-022526-j9kg00qf 5300 29 the the DT cord-022526-j9kg00qf 5300 30 value value NN cord-022526-j9kg00qf 5300 31 of of IN cord-022526-j9kg00qf 5300 32 measuring measure VBG cord-022526-j9kg00qf 5300 33 serum serum NN cord-022526-j9kg00qf 5300 34 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 5300 35 M m CD cord-022526-j9kg00qf 5300 36 concentrations concentration NNS cord-022526-j9kg00qf 5300 37 for for IN cord-022526-j9kg00qf 5300 38 the the DT cord-022526-j9kg00qf 5300 39 diagnosis diagnosis NN cord-022526-j9kg00qf 5300 40 of of IN cord-022526-j9kg00qf 5300 41 lymphoma lymphoma NN cord-022526-j9kg00qf 5300 42 have have VBP cord-022526-j9kg00qf 5300 43 not not RB cord-022526-j9kg00qf 5300 44 been be VBN cord-022526-j9kg00qf 5300 45 evaluated evaluate VBN cord-022526-j9kg00qf 5300 46 . . . cord-022526-j9kg00qf 5301 1 60 60 CD cord-022526-j9kg00qf 5301 2 DNA dna NN cord-022526-j9kg00qf 5301 3 cell cell NN cord-022526-j9kg00qf 5301 4 cycle cycle NN cord-022526-j9kg00qf 5301 5 analysis analysis NN cord-022526-j9kg00qf 5301 6 of of IN cord-022526-j9kg00qf 5301 7 suspect suspect JJ cord-022526-j9kg00qf 5301 8 neoplastic neoplastic JJ cord-022526-j9kg00qf 5301 9 cells cell NNS cord-022526-j9kg00qf 5301 10 has have VBZ cord-022526-j9kg00qf 5301 11 been be VBN cord-022526-j9kg00qf 5301 12 used use VBN cord-022526-j9kg00qf 5301 13 to to TO cord-022526-j9kg00qf 5301 14 detect detect VB cord-022526-j9kg00qf 5301 15 lymphoma lymphoma NN cord-022526-j9kg00qf 5301 16 in in IN cord-022526-j9kg00qf 5301 17 equine equine JJ cord-022526-j9kg00qf 5301 18 patients patient NNS cord-022526-j9kg00qf 5301 19 confirmed confirm VBD cord-022526-j9kg00qf 5301 20 with with IN cord-022526-j9kg00qf 5301 21 the the DT cord-022526-j9kg00qf 5301 22 disease disease NN cord-022526-j9kg00qf 5301 23 . . . cord-022526-j9kg00qf 5302 1 This this DT cord-022526-j9kg00qf 5302 2 method method NN cord-022526-j9kg00qf 5302 3 of of IN cord-022526-j9kg00qf 5302 4 evaluating evaluate VBG cord-022526-j9kg00qf 5302 5 fluid fluid NN cord-022526-j9kg00qf 5302 6 or or CC cord-022526-j9kg00qf 5302 7 tissues tissue NNS cord-022526-j9kg00qf 5302 8 aspirates aspirate NNS cord-022526-j9kg00qf 5302 9 may may MD cord-022526-j9kg00qf 5302 10 increase increase VB cord-022526-j9kg00qf 5302 11 the the DT cord-022526-j9kg00qf 5302 12 accuracy accuracy NN cord-022526-j9kg00qf 5302 13 for for IN cord-022526-j9kg00qf 5302 14 diagnosing diagnose VBG cord-022526-j9kg00qf 5302 15 neoplasia neoplasia NN cord-022526-j9kg00qf 5302 16 in in IN cord-022526-j9kg00qf 5302 17 the the DT cord-022526-j9kg00qf 5302 18 future future NN cord-022526-j9kg00qf 5302 19 . . . cord-022526-j9kg00qf 5303 1 61 61 CD cord-022526-j9kg00qf 5304 1 A a DT cord-022526-j9kg00qf 5304 2 complete complete JJ cord-022526-j9kg00qf 5304 3 evaluation evaluation NN cord-022526-j9kg00qf 5304 4 of of IN cord-022526-j9kg00qf 5304 5 the the DT cord-022526-j9kg00qf 5304 6 oral oral JJ cord-022526-j9kg00qf 5304 7 cavity cavity NN cord-022526-j9kg00qf 5304 8 may may MD cord-022526-j9kg00qf 5304 9 include include VB cord-022526-j9kg00qf 5304 10 using use VBG cord-022526-j9kg00qf 5304 11 a a DT cord-022526-j9kg00qf 5304 12 full full JJ cord-022526-j9kg00qf 5304 13 - - HYPH cord-022526-j9kg00qf 5304 14 mouth mouth NN cord-022526-j9kg00qf 5304 15 speculum speculum NN cord-022526-j9kg00qf 5304 16 , , , cord-022526-j9kg00qf 5304 17 radiographs radiograph NNS cord-022526-j9kg00qf 5304 18 , , , cord-022526-j9kg00qf 5304 19 and and CC cord-022526-j9kg00qf 5304 20 endoscopy endoscopy NN cord-022526-j9kg00qf 5304 21 of of IN cord-022526-j9kg00qf 5304 22 the the DT cord-022526-j9kg00qf 5304 23 pharynx pharynx NN cord-022526-j9kg00qf 5304 24 . . . cord-022526-j9kg00qf 5305 1 Evaluation evaluation NN cord-022526-j9kg00qf 5305 2 of of IN cord-022526-j9kg00qf 5305 3 the the DT cord-022526-j9kg00qf 5305 4 esophagus esophagus NN cord-022526-j9kg00qf 5305 5 and and CC cord-022526-j9kg00qf 5305 6 stomach stomach NN cord-022526-j9kg00qf 5305 7 with with IN cord-022526-j9kg00qf 5305 8 a a DT cord-022526-j9kg00qf 5305 9 3-m 3-m CD cord-022526-j9kg00qf 5305 10 endoscope endoscope NN cord-022526-j9kg00qf 5305 11 can can MD cord-022526-j9kg00qf 5305 12 reveal reveal VB cord-022526-j9kg00qf 5305 13 intralumenal intralumenal JJ cord-022526-j9kg00qf 5305 14 masses masse NNS cord-022526-j9kg00qf 5305 15 . . . cord-022526-j9kg00qf 5306 1 11 11 CD cord-022526-j9kg00qf 5307 1 Pleuroscopy Pleuroscopy NNP cord-022526-j9kg00qf 5307 2 has have VBZ cord-022526-j9kg00qf 5307 3 been be VBN cord-022526-j9kg00qf 5307 4 used use VBN cord-022526-j9kg00qf 5307 5 to to TO cord-022526-j9kg00qf 5307 6 obtain obtain VB cord-022526-j9kg00qf 5307 7 biopsy biopsy NN cord-022526-j9kg00qf 5307 8 samples sample NNS cord-022526-j9kg00qf 5307 9 of of IN cord-022526-j9kg00qf 5307 10 extralumenal extralumenal JJ cord-022526-j9kg00qf 5307 11 masses masse NNS cord-022526-j9kg00qf 5307 12 surrounding surround VBG cord-022526-j9kg00qf 5307 13 the the DT cord-022526-j9kg00qf 5307 14 esophagus esophagus NN cord-022526-j9kg00qf 5307 15 . . . cord-022526-j9kg00qf 5308 1 49 49 CD cord-022526-j9kg00qf 5309 1 Contrast contrast NN cord-022526-j9kg00qf 5309 2 radiography radiography NN cord-022526-j9kg00qf 5309 3 can can MD cord-022526-j9kg00qf 5309 4 assist assist VB cord-022526-j9kg00qf 5309 5 in in IN cord-022526-j9kg00qf 5309 6 the the DT cord-022526-j9kg00qf 5309 7 diagnosis diagnosis NN cord-022526-j9kg00qf 5309 8 of of IN cord-022526-j9kg00qf 5309 9 neoplasia neoplasia NN cord-022526-j9kg00qf 5309 10 within within IN cord-022526-j9kg00qf 5309 11 the the DT cord-022526-j9kg00qf 5309 12 wall wall NN cord-022526-j9kg00qf 5309 13 or or CC cord-022526-j9kg00qf 5309 14 outside outside IN cord-022526-j9kg00qf 5309 15 of of IN cord-022526-j9kg00qf 5309 16 the the DT cord-022526-j9kg00qf 5309 17 esophagus esophagus NN cord-022526-j9kg00qf 5309 18 . . . cord-022526-j9kg00qf 5310 1 49 49 CD cord-022526-j9kg00qf 5310 2 , , , cord-022526-j9kg00qf 5310 3 62 62 CD cord-022526-j9kg00qf 5310 4 Ultrasonography ultrasonography NN cord-022526-j9kg00qf 5310 5 of of IN cord-022526-j9kg00qf 5310 6 the the DT cord-022526-j9kg00qf 5310 7 stomach stomach NN cord-022526-j9kg00qf 5310 8 , , , cord-022526-j9kg00qf 5310 9 small small JJ cord-022526-j9kg00qf 5310 10 intestine intestine NN cord-022526-j9kg00qf 5310 11 , , , cord-022526-j9kg00qf 5310 12 cecum cecum NN cord-022526-j9kg00qf 5310 13 , , , cord-022526-j9kg00qf 5310 14 and and CC cord-022526-j9kg00qf 5310 15 large large JJ cord-022526-j9kg00qf 5310 16 colon colon NN cord-022526-j9kg00qf 5310 17 is be VBZ cord-022526-j9kg00qf 5310 18 useful useful JJ cord-022526-j9kg00qf 5310 19 in in IN cord-022526-j9kg00qf 5310 20 detecting detect VBG cord-022526-j9kg00qf 5310 21 intestinal intestinal JJ cord-022526-j9kg00qf 5310 22 wall wall NN cord-022526-j9kg00qf 5310 23 thickness thickness NN cord-022526-j9kg00qf 5310 24 , , , cord-022526-j9kg00qf 5310 25 abdominal abdominal JJ cord-022526-j9kg00qf 5310 26 masses masse NNS cord-022526-j9kg00qf 5310 27 , , , cord-022526-j9kg00qf 5310 28 and and CC cord-022526-j9kg00qf 5310 29 excessive excessive JJ cord-022526-j9kg00qf 5310 30 peritoneal peritoneal JJ cord-022526-j9kg00qf 5310 31 fluid fluid NN cord-022526-j9kg00qf 5310 32 . . . cord-022526-j9kg00qf 5311 1 63 63 CD cord-022526-j9kg00qf 5311 2 Identification identification NN cord-022526-j9kg00qf 5311 3 of of IN cord-022526-j9kg00qf 5311 4 neoplasia neoplasia NN cord-022526-j9kg00qf 5311 5 in in IN cord-022526-j9kg00qf 5311 6 the the DT cord-022526-j9kg00qf 5311 7 liver liver NN cord-022526-j9kg00qf 5311 8 , , , cord-022526-j9kg00qf 5311 9 kidney kidney NN cord-022526-j9kg00qf 5311 10 or or CC cord-022526-j9kg00qf 5311 11 spleen spleen NN cord-022526-j9kg00qf 5311 12 may may MD cord-022526-j9kg00qf 5311 13 support support VB cord-022526-j9kg00qf 5311 14 metastasis metastasis NN cord-022526-j9kg00qf 5311 15 to to IN cord-022526-j9kg00qf 5311 16 other other JJ cord-022526-j9kg00qf 5311 17 parts part NNS cord-022526-j9kg00qf 5311 18 of of IN cord-022526-j9kg00qf 5311 19 the the DT cord-022526-j9kg00qf 5311 20 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5311 21 tract tract NN cord-022526-j9kg00qf 5311 22 or or CC cord-022526-j9kg00qf 5311 23 lymph lymph NN cord-022526-j9kg00qf 5311 24 nodes node NNS cord-022526-j9kg00qf 5311 25 . . . cord-022526-j9kg00qf 5312 1 Laparoscopy laparoscopy JJ cord-022526-j9kg00qf 5312 2 and and CC cord-022526-j9kg00qf 5312 3 exploratory exploratory JJ cord-022526-j9kg00qf 5312 4 laparotomy laparotomy NN cord-022526-j9kg00qf 5312 5 often often RB cord-022526-j9kg00qf 5312 6 are be VBP cord-022526-j9kg00qf 5312 7 required require VBN cord-022526-j9kg00qf 5312 8 to to TO cord-022526-j9kg00qf 5312 9 obtain obtain VB cord-022526-j9kg00qf 5312 10 a a DT cord-022526-j9kg00qf 5312 11 final final JJ cord-022526-j9kg00qf 5312 12 diagnosis diagnosis NN cord-022526-j9kg00qf 5312 13 . . . cord-022526-j9kg00qf 5313 1 64 64 CD cord-022526-j9kg00qf 5313 2 _SP cord-022526-j9kg00qf 5314 1 Lymphoma Lymphoma NNP cord-022526-j9kg00qf 5314 2 is be VBZ cord-022526-j9kg00qf 5314 3 the the DT cord-022526-j9kg00qf 5314 4 most most RBS cord-022526-j9kg00qf 5314 5 common common JJ cord-022526-j9kg00qf 5314 6 neoplasia neoplasia NN cord-022526-j9kg00qf 5314 7 in in IN cord-022526-j9kg00qf 5314 8 the the DT cord-022526-j9kg00qf 5314 9 horse horse NN cord-022526-j9kg00qf 5314 10 and and CC cord-022526-j9kg00qf 5314 11 has have VBZ cord-022526-j9kg00qf 5314 12 been be VBN cord-022526-j9kg00qf 5314 13 divided divide VBN cord-022526-j9kg00qf 5314 14 into into IN cord-022526-j9kg00qf 5314 15 four four CD cord-022526-j9kg00qf 5314 16 categories category NNS cord-022526-j9kg00qf 5314 17 . . . cord-022526-j9kg00qf 5315 1 This this DT cord-022526-j9kg00qf 5315 2 section section NN cord-022526-j9kg00qf 5315 3 covers cover VBZ cord-022526-j9kg00qf 5315 4 only only RB cord-022526-j9kg00qf 5315 5 the the DT cord-022526-j9kg00qf 5315 6 intestinal intestinal JJ cord-022526-j9kg00qf 5315 7 / / SYM cord-022526-j9kg00qf 5315 8 alimentary alimentary JJ cord-022526-j9kg00qf 5315 9 form form NN cord-022526-j9kg00qf 5315 10 . . . cord-022526-j9kg00qf 5316 1 In in IN cord-022526-j9kg00qf 5316 2 the the DT cord-022526-j9kg00qf 5316 3 past past NN cord-022526-j9kg00qf 5316 4 , , , cord-022526-j9kg00qf 5316 5 lymphoma lymphoma NN cord-022526-j9kg00qf 5316 6 has have VBZ cord-022526-j9kg00qf 5316 7 been be VBN cord-022526-j9kg00qf 5316 8 called call VBN cord-022526-j9kg00qf 5316 9 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5316 10 , , , cord-022526-j9kg00qf 5316 11 but but CC cord-022526-j9kg00qf 5316 12 the the DT cord-022526-j9kg00qf 5316 13 preferred preferred JJ cord-022526-j9kg00qf 5316 14 term term NN cord-022526-j9kg00qf 5316 15 by by IN cord-022526-j9kg00qf 5316 16 oncologists oncologist NNS cord-022526-j9kg00qf 5316 17 is be VBZ cord-022526-j9kg00qf 5316 18 lymphoma lymphoma NN cord-022526-j9kg00qf 5316 19 because because IN cord-022526-j9kg00qf 5316 20 no no DT cord-022526-j9kg00qf 5316 21 benign benign JJ cord-022526-j9kg00qf 5316 22 form form NN cord-022526-j9kg00qf 5316 23 of of IN cord-022526-j9kg00qf 5316 24 this this DT cord-022526-j9kg00qf 5316 25 disease disease NN cord-022526-j9kg00qf 5316 26 exists exist VBZ cord-022526-j9kg00qf 5316 27 . . . cord-022526-j9kg00qf 5317 1 2 2 CD cord-022526-j9kg00qf 5317 2 Lymphoma Lymphoma NNP cord-022526-j9kg00qf 5317 3 originates originate VBZ cord-022526-j9kg00qf 5317 4 from from IN cord-022526-j9kg00qf 5317 5 lymphoid lymphoid JJ cord-022526-j9kg00qf 5317 6 tissue tissue NN cord-022526-j9kg00qf 5317 7 and and CC cord-022526-j9kg00qf 5317 8 predominantly predominantly RB cord-022526-j9kg00qf 5317 9 affects affect VBZ cord-022526-j9kg00qf 5317 10 the the DT cord-022526-j9kg00qf 5317 11 small small JJ cord-022526-j9kg00qf 5317 12 intestine intestine NN cord-022526-j9kg00qf 5317 13 and and CC cord-022526-j9kg00qf 5317 14 intestinal intestinal JJ cord-022526-j9kg00qf 5317 15 lymph lymph NN cord-022526-j9kg00qf 5317 16 nodes node NNS cord-022526-j9kg00qf 5317 17 . . . cord-022526-j9kg00qf 5318 1 Chronic chronic JJ cord-022526-j9kg00qf 5318 2 weight weight NN cord-022526-j9kg00qf 5318 3 loss loss NN cord-022526-j9kg00qf 5318 4 from from IN cord-022526-j9kg00qf 5318 5 malabsorption malabsorption NN cord-022526-j9kg00qf 5318 6 , , , cord-022526-j9kg00qf 5318 7 intermittent intermittent JJ cord-022526-j9kg00qf 5318 8 colic colic NN cord-022526-j9kg00qf 5318 9 , , , cord-022526-j9kg00qf 5318 10 and and CC cord-022526-j9kg00qf 5318 11 fever fever NN cord-022526-j9kg00qf 5318 12 are be VBP cord-022526-j9kg00qf 5318 13 the the DT cord-022526-j9kg00qf 5318 14 most most RBS cord-022526-j9kg00qf 5318 15 common common JJ cord-022526-j9kg00qf 5318 16 clinical clinical JJ cord-022526-j9kg00qf 5318 17 findings finding NNS cord-022526-j9kg00qf 5318 18 . . . cord-022526-j9kg00qf 5319 1 27 27 CD cord-022526-j9kg00qf 5319 2 , , , cord-022526-j9kg00qf 5319 3 65 65 CD cord-022526-j9kg00qf 5319 4 Chronic chronic JJ cord-022526-j9kg00qf 5319 5 diarrhea diarrhea NN cord-022526-j9kg00qf 5319 6 has have VBZ cord-022526-j9kg00qf 5319 7 been be VBN cord-022526-j9kg00qf 5319 8 reported report VBN cord-022526-j9kg00qf 5319 9 in in IN cord-022526-j9kg00qf 5319 10 some some DT cord-022526-j9kg00qf 5319 11 cases case NNS cord-022526-j9kg00qf 5319 12 . . . cord-022526-j9kg00qf 5320 1 66 66 CD cord-022526-j9kg00qf 5321 1 Paraneoplastic paraneoplastic JJ cord-022526-j9kg00qf 5321 2 pruritus pruritus NN cord-022526-j9kg00qf 5321 3 and and CC cord-022526-j9kg00qf 5321 4 alopecia alopecia NNS cord-022526-j9kg00qf 5321 5 have have VBP cord-022526-j9kg00qf 5321 6 been be VBN cord-022526-j9kg00qf 5321 7 identified identify VBN cord-022526-j9kg00qf 5321 8 in in IN cord-022526-j9kg00qf 5321 9 one one CD cord-022526-j9kg00qf 5321 10 case case NN cord-022526-j9kg00qf 5321 11 of of IN cord-022526-j9kg00qf 5321 12 diffuse diffuse JJ cord-022526-j9kg00qf 5321 13 lymphoma lymphoma NN cord-022526-j9kg00qf 5321 14 . . . cord-022526-j9kg00qf 5322 1 67 67 CD cord-022526-j9kg00qf 5323 1 One one CD cord-022526-j9kg00qf 5323 2 generally generally RB cord-022526-j9kg00qf 5323 3 does do VBZ cord-022526-j9kg00qf 5323 4 not not RB cord-022526-j9kg00qf 5323 5 note note VB cord-022526-j9kg00qf 5323 6 peripheral peripheral JJ cord-022526-j9kg00qf 5323 7 lymphadenopathy lymphadenopathy NN cord-022526-j9kg00qf 5323 8 , , , cord-022526-j9kg00qf 5323 9 but but CC cord-022526-j9kg00qf 5323 10 one one PRP cord-022526-j9kg00qf 5323 11 may may MD cord-022526-j9kg00qf 5323 12 palpate palpate VB cord-022526-j9kg00qf 5323 13 enlargement enlargement NN cord-022526-j9kg00qf 5323 14 of of IN cord-022526-j9kg00qf 5323 15 the the DT cord-022526-j9kg00qf 5323 16 intestinal intestinal JJ cord-022526-j9kg00qf 5323 17 lymph lymph NN cord-022526-j9kg00qf 5323 18 nodes node NNS cord-022526-j9kg00qf 5323 19 on on IN cord-022526-j9kg00qf 5323 20 rectal rectal JJ cord-022526-j9kg00qf 5323 21 examination examination NN cord-022526-j9kg00qf 5323 22 . . . cord-022526-j9kg00qf 5324 1 4 4 CD cord-022526-j9kg00qf 5324 2 Large large JJ cord-022526-j9kg00qf 5324 3 colon colon NN cord-022526-j9kg00qf 5324 4 resection resection NN cord-022526-j9kg00qf 5324 5 for for IN cord-022526-j9kg00qf 5324 6 treatment treatment NN cord-022526-j9kg00qf 5324 7 of of IN cord-022526-j9kg00qf 5324 8 lymphoma lymphoma NN cord-022526-j9kg00qf 5324 9 in in IN cord-022526-j9kg00qf 5324 10 horses horse NNS cord-022526-j9kg00qf 5324 11 has have VBZ cord-022526-j9kg00qf 5324 12 increased increase VBN cord-022526-j9kg00qf 5324 13 short short JJ cord-022526-j9kg00qf 5324 14 - - HYPH cord-022526-j9kg00qf 5324 15 term term NN cord-022526-j9kg00qf 5324 16 survival survival NN cord-022526-j9kg00qf 5324 17 in in IN cord-022526-j9kg00qf 5324 18 two two CD cord-022526-j9kg00qf 5324 19 horses horse NNS cord-022526-j9kg00qf 5324 20 . . . cord-022526-j9kg00qf 5325 1 35 35 CD cord-022526-j9kg00qf 5325 2 Chemotherapy chemotherapy NN cord-022526-j9kg00qf 5325 3 in in IN cord-022526-j9kg00qf 5325 4 two two CD cord-022526-j9kg00qf 5325 5 mares mare NNS cord-022526-j9kg00qf 5325 6 that that WDT cord-022526-j9kg00qf 5325 7 were be VBD cord-022526-j9kg00qf 5325 8 pregnant pregnant JJ cord-022526-j9kg00qf 5325 9 extended extend VBD cord-022526-j9kg00qf 5325 10 their -PRON- PRP$ cord-022526-j9kg00qf 5325 11 lives life NNS cord-022526-j9kg00qf 5325 12 long long RB cord-022526-j9kg00qf 5325 13 enough enough RB cord-022526-j9kg00qf 5325 14 to to TO cord-022526-j9kg00qf 5325 15 foal foal VB cord-022526-j9kg00qf 5325 16 normally normally RB cord-022526-j9kg00qf 5325 17 . . . cord-022526-j9kg00qf 5326 1 68 68 CD cord-022526-j9kg00qf 5326 2 Long long JJ cord-022526-j9kg00qf 5326 3 - - HYPH cord-022526-j9kg00qf 5326 4 term term NN cord-022526-j9kg00qf 5326 5 prognosis prognosis NN cord-022526-j9kg00qf 5326 6 for for IN cord-022526-j9kg00qf 5326 7 intestinal intestinal JJ cord-022526-j9kg00qf 5326 8 lymphoma lymphoma NN cord-022526-j9kg00qf 5326 9 is be VBZ cord-022526-j9kg00qf 5326 10 poor poor JJ cord-022526-j9kg00qf 5326 11 . . . cord-022526-j9kg00qf 5327 1 Squamous squamous JJ cord-022526-j9kg00qf 5327 2 cell cell NN cord-022526-j9kg00qf 5327 3 carcinoma carcinoma NN cord-022526-j9kg00qf 5327 4 ( ( -LRB- cord-022526-j9kg00qf 5327 5 SCC SCC NNP cord-022526-j9kg00qf 5327 6 ) ) -RRB- cord-022526-j9kg00qf 5327 7 is be VBZ cord-022526-j9kg00qf 5327 8 a a DT cord-022526-j9kg00qf 5327 9 malignant malignant JJ cord-022526-j9kg00qf 5327 10 tumor tumor NN cord-022526-j9kg00qf 5327 11 of of IN cord-022526-j9kg00qf 5327 12 the the DT cord-022526-j9kg00qf 5327 13 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5327 14 epithelium epithelium NN cord-022526-j9kg00qf 5327 15 . . . cord-022526-j9kg00qf 5328 1 SCC SCC NNP cord-022526-j9kg00qf 5328 2 is be VBZ cord-022526-j9kg00qf 5328 3 the the DT cord-022526-j9kg00qf 5328 4 second second JJ cord-022526-j9kg00qf 5328 5 most most RBS cord-022526-j9kg00qf 5328 6 common common JJ cord-022526-j9kg00qf 5328 7 neoplasia neoplasia NN cord-022526-j9kg00qf 5328 8 in in IN cord-022526-j9kg00qf 5328 9 the the DT cord-022526-j9kg00qf 5328 10 horse horse NN cord-022526-j9kg00qf 5328 11 and and CC cord-022526-j9kg00qf 5328 12 is be VBZ cord-022526-j9kg00qf 5328 13 the the DT cord-022526-j9kg00qf 5328 14 most most RBS cord-022526-j9kg00qf 5328 15 common common JJ cord-022526-j9kg00qf 5328 16 oral oral JJ cord-022526-j9kg00qf 5328 17 neoplasia neoplasia NN cord-022526-j9kg00qf 5328 18 . . . cord-022526-j9kg00qf 5329 1 However however RB cord-022526-j9kg00qf 5329 2 , , , cord-022526-j9kg00qf 5329 3 the the DT cord-022526-j9kg00qf 5329 4 incidence incidence NN cord-022526-j9kg00qf 5329 5 of of IN cord-022526-j9kg00qf 5329 6 SCC SCC NNP cord-022526-j9kg00qf 5329 7 is be VBZ cord-022526-j9kg00qf 5329 8 rare rare JJ cord-022526-j9kg00qf 5329 9 . . . cord-022526-j9kg00qf 5330 1 10 10 CD cord-022526-j9kg00qf 5330 2 , , , cord-022526-j9kg00qf 5330 3 16 16 CD cord-022526-j9kg00qf 5330 4 , , , cord-022526-j9kg00qf 5330 5 50 50 CD cord-022526-j9kg00qf 5331 1 In in IN cord-022526-j9kg00qf 5331 2 the the DT cord-022526-j9kg00qf 5331 3 oral oral JJ cord-022526-j9kg00qf 5331 4 cavity cavity NN cord-022526-j9kg00qf 5331 5 SCC SCC NNP cord-022526-j9kg00qf 5331 6 may may MD cord-022526-j9kg00qf 5331 7 affect affect VB cord-022526-j9kg00qf 5331 8 the the DT cord-022526-j9kg00qf 5331 9 lips lip NNS cord-022526-j9kg00qf 5331 10 , , , cord-022526-j9kg00qf 5331 11 tongue tongue NN cord-022526-j9kg00qf 5331 12 , , , cord-022526-j9kg00qf 5331 13 hard hard JJ cord-022526-j9kg00qf 5331 14 palate palate NN cord-022526-j9kg00qf 5331 15 , , , cord-022526-j9kg00qf 5331 16 pharynx pharynx NN cord-022526-j9kg00qf 5331 17 , , , cord-022526-j9kg00qf 5331 18 and and CC cord-022526-j9kg00qf 5331 19 mucosa mucosa JJ cord-022526-j9kg00qf 5331 20 . . . cord-022526-j9kg00qf 5332 1 69 69 CD cord-022526-j9kg00qf 5332 2 , , , cord-022526-j9kg00qf 5332 3 70 70 CD cord-022526-j9kg00qf 5332 4 Treatment treatment NN cord-022526-j9kg00qf 5332 5 for for IN cord-022526-j9kg00qf 5332 6 SCC SCC NNP cord-022526-j9kg00qf 5332 7 in in IN cord-022526-j9kg00qf 5332 8 the the DT cord-022526-j9kg00qf 5332 9 oral oral JJ cord-022526-j9kg00qf 5332 10 cavity cavity NN cord-022526-j9kg00qf 5332 11 may may MD cord-022526-j9kg00qf 5332 12 involve involve VB cord-022526-j9kg00qf 5332 13 surgical surgical JJ cord-022526-j9kg00qf 5332 14 resection resection NN cord-022526-j9kg00qf 5332 15 , , , cord-022526-j9kg00qf 5332 16 iridium-192 iridium-192 JJ cord-022526-j9kg00qf 5332 17 brachytherapy brachytherapy NN cord-022526-j9kg00qf 5332 18 , , , cord-022526-j9kg00qf 5332 19 5-fluorouracil 5-fluorouracil CD cord-022526-j9kg00qf 5332 20 , , , cord-022526-j9kg00qf 5332 21 or or CC cord-022526-j9kg00qf 5332 22 intralesional intralesional JJ cord-022526-j9kg00qf 5332 23 cisplatin cisplatin NN cord-022526-j9kg00qf 5332 24 . . . cord-022526-j9kg00qf 5333 1 5 5 LS cord-022526-j9kg00qf 5333 2 , , , cord-022526-j9kg00qf 5333 3 [ [ -LRB- cord-022526-j9kg00qf 5333 4 71 71 CD cord-022526-j9kg00qf 5333 5 ] ] -RRB- cord-022526-j9kg00qf 5333 6 [ [ -LRB- cord-022526-j9kg00qf 5333 7 72 72 CD cord-022526-j9kg00qf 5333 8 ] ] -RRB- cord-022526-j9kg00qf 5334 1 [ [ -LRB- cord-022526-j9kg00qf 5334 2 73 73 CD cord-022526-j9kg00qf 5334 3 ] ] -RRB- cord-022526-j9kg00qf 5335 1 The the DT cord-022526-j9kg00qf 5335 2 prognosis prognosis NN cord-022526-j9kg00qf 5335 3 for for IN cord-022526-j9kg00qf 5335 4 survival survival NN cord-022526-j9kg00qf 5335 5 is be VBZ cord-022526-j9kg00qf 5335 6 good good JJ cord-022526-j9kg00qf 5335 7 if if IN cord-022526-j9kg00qf 5335 8 complete complete JJ cord-022526-j9kg00qf 5335 9 removal removal NN cord-022526-j9kg00qf 5335 10 of of IN cord-022526-j9kg00qf 5335 11 the the DT cord-022526-j9kg00qf 5335 12 tumor tumor NN cord-022526-j9kg00qf 5335 13 is be VBZ cord-022526-j9kg00qf 5335 14 possible possible JJ cord-022526-j9kg00qf 5335 15 . . . cord-022526-j9kg00qf 5336 1 Metastasis metastasis NN cord-022526-j9kg00qf 5336 2 beyond beyond IN cord-022526-j9kg00qf 5336 3 the the DT cord-022526-j9kg00qf 5336 4 regional regional JJ cord-022526-j9kg00qf 5336 5 lymph lymph NN cord-022526-j9kg00qf 5336 6 nodes node NNS cord-022526-j9kg00qf 5336 7 is be VBZ cord-022526-j9kg00qf 5336 8 rare rare JJ cord-022526-j9kg00qf 5336 9 for for IN cord-022526-j9kg00qf 5336 10 oral oral JJ cord-022526-j9kg00qf 5336 11 SCC SCC NNP cord-022526-j9kg00qf 5336 12 . . . cord-022526-j9kg00qf 5337 1 Squamous squamous JJ cord-022526-j9kg00qf 5337 2 cell cell NN cord-022526-j9kg00qf 5337 3 carcinoma carcinoma NN cord-022526-j9kg00qf 5337 4 is be VBZ cord-022526-j9kg00qf 5337 5 the the DT cord-022526-j9kg00qf 5337 6 most most RBS cord-022526-j9kg00qf 5337 7 common common JJ cord-022526-j9kg00qf 5337 8 tumor tumor NN cord-022526-j9kg00qf 5337 9 of of IN cord-022526-j9kg00qf 5337 10 the the DT cord-022526-j9kg00qf 5337 11 stomach stomach NN cord-022526-j9kg00qf 5337 12 and and CC cord-022526-j9kg00qf 5337 13 esophagus esophagus NN cord-022526-j9kg00qf 5337 14 11 11 CD cord-022526-j9kg00qf 5337 15 , , , cord-022526-j9kg00qf 5337 16 16 16 CD cord-022526-j9kg00qf 5337 17 and and CC cord-022526-j9kg00qf 5337 18 can can MD cord-022526-j9kg00qf 5337 19 invade invade VB cord-022526-j9kg00qf 5337 20 these these DT cord-022526-j9kg00qf 5337 21 areas area NNS cord-022526-j9kg00qf 5337 22 and and CC cord-022526-j9kg00qf 5337 23 metastasize metastasize VB cord-022526-j9kg00qf 5337 24 to to IN cord-022526-j9kg00qf 5337 25 the the DT cord-022526-j9kg00qf 5337 26 lymph lymph NN cord-022526-j9kg00qf 5337 27 nodes node NNS cord-022526-j9kg00qf 5337 28 and and CC cord-022526-j9kg00qf 5337 29 lungs lung NNS cord-022526-j9kg00qf 5337 30 . . . cord-022526-j9kg00qf 5338 1 Abnormal abnormal JJ cord-022526-j9kg00qf 5338 2 masses masse NNS cord-022526-j9kg00qf 5338 3 were be VBD cord-022526-j9kg00qf 5338 4 palpated palpate VBN cord-022526-j9kg00qf 5338 5 on on IN cord-022526-j9kg00qf 5338 6 rectal rectal JJ cord-022526-j9kg00qf 5338 7 examination examination NN cord-022526-j9kg00qf 5338 8 in in IN cord-022526-j9kg00qf 5338 9 four four CD cord-022526-j9kg00qf 5338 10 of of IN cord-022526-j9kg00qf 5338 11 five five CD cord-022526-j9kg00qf 5338 12 cases case NNS cord-022526-j9kg00qf 5338 13 of of IN cord-022526-j9kg00qf 5338 14 gastric gastric JJ cord-022526-j9kg00qf 5338 15 SCC SCC NNP cord-022526-j9kg00qf 5338 16 . . . cord-022526-j9kg00qf 5339 1 16 16 CD cord-022526-j9kg00qf 5339 2 Treatment treatment NN cord-022526-j9kg00qf 5339 3 by by IN cord-022526-j9kg00qf 5339 4 surgical surgical JJ cord-022526-j9kg00qf 5339 5 resection resection NN cord-022526-j9kg00qf 5339 6 is be VBZ cord-022526-j9kg00qf 5339 7 not not RB cord-022526-j9kg00qf 5339 8 possible possible JJ cord-022526-j9kg00qf 5339 9 in in IN cord-022526-j9kg00qf 5339 10 most most JJS cord-022526-j9kg00qf 5339 11 cases case NNS cord-022526-j9kg00qf 5339 12 and and CC cord-022526-j9kg00qf 5339 13 the the DT cord-022526-j9kg00qf 5339 14 horses horse NNS cord-022526-j9kg00qf 5339 15 die die VBP cord-022526-j9kg00qf 5339 16 or or CC cord-022526-j9kg00qf 5339 17 are be VBP cord-022526-j9kg00qf 5339 18 euthanized euthanize VBN cord-022526-j9kg00qf 5339 19 . . . cord-022526-j9kg00qf 5340 1 2 2 LS cord-022526-j9kg00qf 5341 1 Adenocarcinoma Adenocarcinoma NNP cord-022526-j9kg00qf 5341 2 is be VBZ cord-022526-j9kg00qf 5341 3 a a DT cord-022526-j9kg00qf 5341 4 malignant malignant JJ cord-022526-j9kg00qf 5341 5 tumor tumor NN cord-022526-j9kg00qf 5341 6 that that WDT cord-022526-j9kg00qf 5341 7 can can MD cord-022526-j9kg00qf 5341 8 occur occur VB cord-022526-j9kg00qf 5341 9 in in IN cord-022526-j9kg00qf 5341 10 the the DT cord-022526-j9kg00qf 5341 11 small small JJ cord-022526-j9kg00qf 5341 12 intestine intestine NN cord-022526-j9kg00qf 5341 13 , , , cord-022526-j9kg00qf 5341 14 cecum cecum NN cord-022526-j9kg00qf 5341 15 , , , cord-022526-j9kg00qf 5341 16 and and CC cord-022526-j9kg00qf 5341 17 large large JJ cord-022526-j9kg00qf 5341 18 colon colon NN cord-022526-j9kg00qf 5341 19 . . . cord-022526-j9kg00qf 5342 1 18 18 CD cord-022526-j9kg00qf 5343 1 The the DT cord-022526-j9kg00qf 5343 2 tumor tumor NN cord-022526-j9kg00qf 5343 3 arises arise VBZ cord-022526-j9kg00qf 5343 4 from from IN cord-022526-j9kg00qf 5343 5 the the DT cord-022526-j9kg00qf 5343 6 glandular glandular JJ cord-022526-j9kg00qf 5343 7 crypts crypt NNS cord-022526-j9kg00qf 5343 8 of of IN cord-022526-j9kg00qf 5343 9 the the DT cord-022526-j9kg00qf 5343 10 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5343 11 tract tract NN cord-022526-j9kg00qf 5343 12 and and CC cord-022526-j9kg00qf 5343 13 has have VBZ cord-022526-j9kg00qf 5343 14 been be VBN cord-022526-j9kg00qf 5343 15 reported report VBN cord-022526-j9kg00qf 5343 16 in in IN cord-022526-j9kg00qf 5343 17 middle middle NN cord-022526-j9kg00qf 5343 18 - - HYPH cord-022526-j9kg00qf 5343 19 aged aged JJ cord-022526-j9kg00qf 5343 20 and and CC cord-022526-j9kg00qf 5343 21 older old JJR cord-022526-j9kg00qf 5343 22 horses horse NNS cord-022526-j9kg00qf 5343 23 . . . cord-022526-j9kg00qf 5344 1 Metastasis metastasis NN cord-022526-j9kg00qf 5344 2 to to IN cord-022526-j9kg00qf 5344 3 the the DT cord-022526-j9kg00qf 5344 4 lymph lymph NN cord-022526-j9kg00qf 5344 5 nodes node NNS cord-022526-j9kg00qf 5344 6 , , , cord-022526-j9kg00qf 5344 7 liver liver NN cord-022526-j9kg00qf 5344 8 , , , cord-022526-j9kg00qf 5344 9 and and CC cord-022526-j9kg00qf 5344 10 lungs lung NNS cord-022526-j9kg00qf 5344 11 can can MD cord-022526-j9kg00qf 5344 12 occur occur VB cord-022526-j9kg00qf 5344 13 . . . cord-022526-j9kg00qf 5345 1 Intestinal intestinal JJ cord-022526-j9kg00qf 5345 2 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5345 3 has have VBZ cord-022526-j9kg00qf 5345 4 been be VBN cord-022526-j9kg00qf 5345 5 reported report VBN cord-022526-j9kg00qf 5345 6 to to TO cord-022526-j9kg00qf 5345 7 metastasize metastasize VB cord-022526-j9kg00qf 5345 8 to to IN cord-022526-j9kg00qf 5345 9 the the DT cord-022526-j9kg00qf 5345 10 bone bone NN cord-022526-j9kg00qf 5345 11 and and CC cord-022526-j9kg00qf 5345 12 was be VBD cord-022526-j9kg00qf 5345 13 diagnosed diagnose VBN cord-022526-j9kg00qf 5345 14 using use VBG cord-022526-j9kg00qf 5345 15 nuclear nuclear JJ cord-022526-j9kg00qf 5345 16 scintigraphy scintigraphy NN cord-022526-j9kg00qf 5345 17 following follow VBG cord-022526-j9kg00qf 5345 18 injection injection NN cord-022526-j9kg00qf 5345 19 of of IN cord-022526-j9kg00qf 5345 20 technetium-99 technetium-99 NNP cord-022526-j9kg00qf 5345 21 m m NNP cord-022526-j9kg00qf 5345 22 hydroxymethylene hydroxymethylene NNP cord-022526-j9kg00qf 5345 23 diphosphate diphosphate NN cord-022526-j9kg00qf 5345 24 . . . cord-022526-j9kg00qf 5346 1 29 29 CD cord-022526-j9kg00qf 5346 2 , , , cord-022526-j9kg00qf 5346 3 32 32 CD cord-022526-j9kg00qf 5347 1 No no DT cord-022526-j9kg00qf 5347 2 reports report NNS cord-022526-j9kg00qf 5347 3 of of IN cord-022526-j9kg00qf 5347 4 successful successful JJ cord-022526-j9kg00qf 5347 5 surgical surgical JJ cord-022526-j9kg00qf 5347 6 resection resection NN cord-022526-j9kg00qf 5347 7 have have VBP cord-022526-j9kg00qf 5347 8 been be VBN cord-022526-j9kg00qf 5347 9 published publish VBN cord-022526-j9kg00qf 5347 10 . . . cord-022526-j9kg00qf 5348 1 Leiomyosarcoma Leiomyosarcoma NNP cord-022526-j9kg00qf 5348 2 is be VBZ cord-022526-j9kg00qf 5348 3 a a DT cord-022526-j9kg00qf 5348 4 malignant malignant JJ cord-022526-j9kg00qf 5348 5 tumor tumor NN cord-022526-j9kg00qf 5348 6 of of IN cord-022526-j9kg00qf 5348 7 the the DT cord-022526-j9kg00qf 5348 8 smooth smooth JJ cord-022526-j9kg00qf 5348 9 muscle muscle NN cord-022526-j9kg00qf 5348 10 lining line VBG cord-022526-j9kg00qf 5348 11 the the DT cord-022526-j9kg00qf 5348 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5348 13 tract tract NN cord-022526-j9kg00qf 5348 14 and and CC cord-022526-j9kg00qf 5348 15 has have VBZ cord-022526-j9kg00qf 5348 16 been be VBN cord-022526-j9kg00qf 5348 17 reported report VBN cord-022526-j9kg00qf 5348 18 in in IN cord-022526-j9kg00qf 5348 19 the the DT cord-022526-j9kg00qf 5348 20 stomach stomach NN cord-022526-j9kg00qf 5348 21 , , , cord-022526-j9kg00qf 5348 22 small small JJ cord-022526-j9kg00qf 5348 23 intestine intestine NN cord-022526-j9kg00qf 5348 24 , , , cord-022526-j9kg00qf 5348 25 and and CC cord-022526-j9kg00qf 5348 26 rectum rectum NN cord-022526-j9kg00qf 5348 27 . . . cord-022526-j9kg00qf 5349 1 13 13 CD cord-022526-j9kg00qf 5349 2 , , , cord-022526-j9kg00qf 5349 3 22 22 CD cord-022526-j9kg00qf 5349 4 , , , cord-022526-j9kg00qf 5349 5 23 23 CD cord-022526-j9kg00qf 5349 6 , , , cord-022526-j9kg00qf 5349 7 40 40 CD cord-022526-j9kg00qf 5349 8 , , , cord-022526-j9kg00qf 5349 9 58 58 CD cord-022526-j9kg00qf 5349 10 In in IN cord-022526-j9kg00qf 5349 11 one one CD cord-022526-j9kg00qf 5349 12 case case NN cord-022526-j9kg00qf 5349 13 report report NN cord-022526-j9kg00qf 5349 14 , , , cord-022526-j9kg00qf 5349 15 gastroscopy gastroscopy NN cord-022526-j9kg00qf 5349 16 could could MD cord-022526-j9kg00qf 5349 17 not not RB cord-022526-j9kg00qf 5349 18 identify identify VB cord-022526-j9kg00qf 5349 19 the the DT cord-022526-j9kg00qf 5349 20 mural mural NN cord-022526-j9kg00qf 5349 21 mass mass NN cord-022526-j9kg00qf 5349 22 in in IN cord-022526-j9kg00qf 5349 23 the the DT cord-022526-j9kg00qf 5349 24 stomach stomach NN cord-022526-j9kg00qf 5349 25 that that WDT cord-022526-j9kg00qf 5349 26 was be VBD cord-022526-j9kg00qf 5349 27 found find VBN cord-022526-j9kg00qf 5349 28 during during IN cord-022526-j9kg00qf 5349 29 exploratory exploratory JJ cord-022526-j9kg00qf 5349 30 surgery surgery NN cord-022526-j9kg00qf 5349 31 . . . cord-022526-j9kg00qf 5350 1 Another another DT cord-022526-j9kg00qf 5350 2 report report NN cord-022526-j9kg00qf 5350 3 describes describe VBZ cord-022526-j9kg00qf 5350 4 a a DT cord-022526-j9kg00qf 5350 5 favorable favorable JJ cord-022526-j9kg00qf 5350 6 outcome outcome NN cord-022526-j9kg00qf 5350 7 for for IN cord-022526-j9kg00qf 5350 8 surgical surgical JJ cord-022526-j9kg00qf 5350 9 resection resection NN cord-022526-j9kg00qf 5350 10 of of IN cord-022526-j9kg00qf 5350 11 a a DT cord-022526-j9kg00qf 5350 12 leiomyosarcoma leiomyosarcoma NN cord-022526-j9kg00qf 5350 13 that that WDT cord-022526-j9kg00qf 5350 14 was be VBD cord-022526-j9kg00qf 5350 15 protruding protrude VBG cord-022526-j9kg00qf 5350 16 from from IN cord-022526-j9kg00qf 5350 17 the the DT cord-022526-j9kg00qf 5350 18 anal anal JJ cord-022526-j9kg00qf 5350 19 sphincter sphincter NN cord-022526-j9kg00qf 5350 20 in in IN cord-022526-j9kg00qf 5350 21 a a DT cord-022526-j9kg00qf 5350 22 4-year 4-year JJ cord-022526-j9kg00qf 5350 23 - - HYPH cord-022526-j9kg00qf 5350 24 old old JJ cord-022526-j9kg00qf 5350 25 Quarter Quarter NNP cord-022526-j9kg00qf 5350 26 Horse Horse NNP cord-022526-j9kg00qf 5350 27 . . . cord-022526-j9kg00qf 5351 1 40 40 CD cord-022526-j9kg00qf 5351 2 Prognosis prognosis NN cord-022526-j9kg00qf 5351 3 for for IN cord-022526-j9kg00qf 5351 4 survival survival NN cord-022526-j9kg00qf 5351 5 is be VBZ cord-022526-j9kg00qf 5351 6 favorable favorable JJ cord-022526-j9kg00qf 5351 7 if if IN cord-022526-j9kg00qf 5351 8 surgical surgical JJ cord-022526-j9kg00qf 5351 9 resection resection NN cord-022526-j9kg00qf 5351 10 is be VBZ cord-022526-j9kg00qf 5351 11 possible possible JJ cord-022526-j9kg00qf 5351 12 . . . cord-022526-j9kg00qf 5352 1 Leiomyoma Leiomyoma NNP cord-022526-j9kg00qf 5352 2 is be VBZ cord-022526-j9kg00qf 5352 3 a a DT cord-022526-j9kg00qf 5352 4 benign benign JJ cord-022526-j9kg00qf 5352 5 tumor tumor NN cord-022526-j9kg00qf 5352 6 of of IN cord-022526-j9kg00qf 5352 7 the the DT cord-022526-j9kg00qf 5352 8 smooth smooth JJ cord-022526-j9kg00qf 5352 9 muscle muscle NN cord-022526-j9kg00qf 5352 10 of of IN cord-022526-j9kg00qf 5352 11 the the DT cord-022526-j9kg00qf 5352 12 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5352 13 tract tract NN cord-022526-j9kg00qf 5352 14 that that WDT cord-022526-j9kg00qf 5352 15 can can MD cord-022526-j9kg00qf 5352 16 occur occur VB cord-022526-j9kg00qf 5352 17 in in IN cord-022526-j9kg00qf 5352 18 the the DT cord-022526-j9kg00qf 5352 19 stomach stomach NN cord-022526-j9kg00qf 5352 20 , , , cord-022526-j9kg00qf 5352 21 small small JJ cord-022526-j9kg00qf 5352 22 intestine intestine NN cord-022526-j9kg00qf 5352 23 , , , cord-022526-j9kg00qf 5352 24 and and CC cord-022526-j9kg00qf 5352 25 small small JJ cord-022526-j9kg00qf 5352 26 colon colon NN cord-022526-j9kg00qf 5352 27 . . . cord-022526-j9kg00qf 5353 1 37 37 CD cord-022526-j9kg00qf 5353 2 , , , cord-022526-j9kg00qf 5353 3 38 38 CD cord-022526-j9kg00qf 5353 4 Clinical clinical JJ cord-022526-j9kg00qf 5353 5 signs sign NNS cord-022526-j9kg00qf 5353 6 are be VBP cord-022526-j9kg00qf 5353 7 consistent consistent JJ cord-022526-j9kg00qf 5353 8 with with IN cord-022526-j9kg00qf 5353 9 intestinal intestinal JJ cord-022526-j9kg00qf 5353 10 obstruction obstruction NN cord-022526-j9kg00qf 5353 11 . . . cord-022526-j9kg00qf 5354 1 Surgical surgical JJ cord-022526-j9kg00qf 5354 2 resection resection NN cord-022526-j9kg00qf 5354 3 and and CC cord-022526-j9kg00qf 5354 4 anastomosis anastomosis NN cord-022526-j9kg00qf 5354 5 of of IN cord-022526-j9kg00qf 5354 6 the the DT cord-022526-j9kg00qf 5354 7 affected affected JJ cord-022526-j9kg00qf 5354 8 portion portion NN cord-022526-j9kg00qf 5354 9 of of IN cord-022526-j9kg00qf 5354 10 the the DT cord-022526-j9kg00qf 5354 11 intestine intestine NN cord-022526-j9kg00qf 5354 12 have have VBP cord-022526-j9kg00qf 5354 13 been be VBN cord-022526-j9kg00qf 5354 14 performed perform VBN cord-022526-j9kg00qf 5354 15 without without IN cord-022526-j9kg00qf 5354 16 complications complication NNS cord-022526-j9kg00qf 5354 17 . . . cord-022526-j9kg00qf 5355 1 Lipoma Lipoma NNP cord-022526-j9kg00qf 5355 2 is be VBZ cord-022526-j9kg00qf 5355 3 a a DT cord-022526-j9kg00qf 5355 4 benign benign JJ cord-022526-j9kg00qf 5355 5 tumor tumor NN cord-022526-j9kg00qf 5355 6 that that WDT cord-022526-j9kg00qf 5355 7 occurs occur VBZ cord-022526-j9kg00qf 5355 8 in in IN cord-022526-j9kg00qf 5355 9 older old JJR cord-022526-j9kg00qf 5355 10 horses horse NNS cord-022526-j9kg00qf 5355 11 ( ( -LRB- cord-022526-j9kg00qf 5355 12 10 10 CD cord-022526-j9kg00qf 5355 13 to to TO cord-022526-j9kg00qf 5355 14 26 26 CD cord-022526-j9kg00qf 5355 15 years year NNS cord-022526-j9kg00qf 5355 16 ) ) -RRB- cord-022526-j9kg00qf 5355 17 and and CC cord-022526-j9kg00qf 5355 18 arises arise VBZ cord-022526-j9kg00qf 5355 19 from from IN cord-022526-j9kg00qf 5355 20 mesenteric mesenteric JJ cord-022526-j9kg00qf 5355 21 adipocytes adipocyte NNS cord-022526-j9kg00qf 5355 22 . . . cord-022526-j9kg00qf 5356 1 The the DT cord-022526-j9kg00qf 5356 2 tumor tumor NN cord-022526-j9kg00qf 5356 3 grows grow VBZ cord-022526-j9kg00qf 5356 4 on on IN cord-022526-j9kg00qf 5356 5 a a DT cord-022526-j9kg00qf 5356 6 stalk stalk NN cord-022526-j9kg00qf 5356 7 that that WDT cord-022526-j9kg00qf 5356 8 wraps wrap VBZ cord-022526-j9kg00qf 5356 9 around around IN cord-022526-j9kg00qf 5356 10 the the DT cord-022526-j9kg00qf 5356 11 intestine intestine NN cord-022526-j9kg00qf 5356 12 , , , cord-022526-j9kg00qf 5356 13 causing cause VBG cord-022526-j9kg00qf 5356 14 a a DT cord-022526-j9kg00qf 5356 15 strangulating strangulating JJ cord-022526-j9kg00qf 5356 16 lesion lesion NN cord-022526-j9kg00qf 5356 17 manifested manifest VBN cord-022526-j9kg00qf 5356 18 clinically clinically RB cord-022526-j9kg00qf 5356 19 by by IN cord-022526-j9kg00qf 5356 20 acute acute JJ cord-022526-j9kg00qf 5356 21 obstructive obstructive JJ cord-022526-j9kg00qf 5356 22 colic colic NN cord-022526-j9kg00qf 5356 23 . . . cord-022526-j9kg00qf 5357 1 Intestinal intestinal JJ cord-022526-j9kg00qf 5357 2 injury injury NN cord-022526-j9kg00qf 5357 3 caused cause VBN cord-022526-j9kg00qf 5357 4 by by IN cord-022526-j9kg00qf 5357 5 pedunculated pedunculated JJ cord-022526-j9kg00qf 5357 6 lipomata lipomata NNP cord-022526-j9kg00qf 5357 7 may may MD cord-022526-j9kg00qf 5357 8 occur occur VB cord-022526-j9kg00qf 5357 9 in in IN cord-022526-j9kg00qf 5357 10 the the DT cord-022526-j9kg00qf 5357 11 small small JJ cord-022526-j9kg00qf 5357 12 intestine intestine NN cord-022526-j9kg00qf 5357 13 , , , cord-022526-j9kg00qf 5357 14 small small JJ cord-022526-j9kg00qf 5357 15 colon colon NN cord-022526-j9kg00qf 5357 16 , , , cord-022526-j9kg00qf 5357 17 and and CC cord-022526-j9kg00qf 5357 18 rectum rectum NN cord-022526-j9kg00qf 5357 19 . . . cord-022526-j9kg00qf 5358 1 Long long JJ cord-022526-j9kg00qf 5358 2 - - HYPH cord-022526-j9kg00qf 5358 3 term term NN cord-022526-j9kg00qf 5358 4 survival survival NN cord-022526-j9kg00qf 5358 5 with with IN cord-022526-j9kg00qf 5358 6 surgical surgical JJ cord-022526-j9kg00qf 5358 7 resection resection NN cord-022526-j9kg00qf 5358 8 and and CC cord-022526-j9kg00qf 5358 9 anastomosis anastomosis NN cord-022526-j9kg00qf 5358 10 of of IN cord-022526-j9kg00qf 5358 11 the the DT cord-022526-j9kg00qf 5358 12 affected affect VBN cord-022526-j9kg00qf 5358 13 segment segment NN cord-022526-j9kg00qf 5358 14 has have VBZ cord-022526-j9kg00qf 5358 15 been be VBN cord-022526-j9kg00qf 5358 16 reported report VBN cord-022526-j9kg00qf 5358 17 to to TO cord-022526-j9kg00qf 5358 18 be be VB cord-022526-j9kg00qf 5358 19 40 40 CD cord-022526-j9kg00qf 5358 20 % % NN cord-022526-j9kg00qf 5358 21 to to TO cord-022526-j9kg00qf 5358 22 50 50 CD cord-022526-j9kg00qf 5358 23 % % NN cord-022526-j9kg00qf 5358 24 . . . cord-022526-j9kg00qf 5359 1 26 26 CD cord-022526-j9kg00qf 5359 2 , , , cord-022526-j9kg00qf 5359 3 74 74 CD cord-022526-j9kg00qf 5359 4 ORAL oral JJ cord-022526-j9kg00qf 5359 5 NEOPLASIA neoplasia NN cord-022526-j9kg00qf 5360 1 Oral oral JJ cord-022526-j9kg00qf 5360 2 cavity cavity NN cord-022526-j9kg00qf 5360 3 neoplasia neoplasia NN cord-022526-j9kg00qf 5360 4 may may MD cord-022526-j9kg00qf 5360 5 involve involve VB cord-022526-j9kg00qf 5360 6 the the DT cord-022526-j9kg00qf 5360 7 dental dental JJ cord-022526-j9kg00qf 5360 8 tissue tissue NN cord-022526-j9kg00qf 5360 9 ( ( -LRB- cord-022526-j9kg00qf 5360 10 odontogenic odontogenic JJ cord-022526-j9kg00qf 5360 11 tumors tumor NNS cord-022526-j9kg00qf 5360 12 ) ) -RRB- cord-022526-j9kg00qf 5360 13 , , , cord-022526-j9kg00qf 5360 14 bone bone NN cord-022526-j9kg00qf 5360 15 ( ( -LRB- cord-022526-j9kg00qf 5360 16 osteogenic osteogenic JJ cord-022526-j9kg00qf 5360 17 tumors tumor NNS cord-022526-j9kg00qf 5360 18 ) ) -RRB- cord-022526-j9kg00qf 5360 19 , , , cord-022526-j9kg00qf 5360 20 or or CC cord-022526-j9kg00qf 5360 21 soft soft JJ cord-022526-j9kg00qf 5360 22 tissues tissue NNS cord-022526-j9kg00qf 5360 23 ( ( -LRB- cord-022526-j9kg00qf 5360 24 see see VB cord-022526-j9kg00qf 5360 25 Box Box NNP cord-022526-j9kg00qf 5360 26 13.16 13.16 CD cord-022526-j9kg00qf 5360 27 - - SYM cord-022526-j9kg00qf 5360 28 1 1 CD cord-022526-j9kg00qf 5360 29 ) ) -RRB- cord-022526-j9kg00qf 5360 30 . . . cord-022526-j9kg00qf 5361 1 Ameloblastoma ameloblastoma NN cord-022526-j9kg00qf 5361 2 occurs occur VBZ cord-022526-j9kg00qf 5361 3 in in IN cord-022526-j9kg00qf 5361 4 horses horse NNS cord-022526-j9kg00qf 5361 5 greater great JJR cord-022526-j9kg00qf 5361 6 than than IN cord-022526-j9kg00qf 5361 7 10 10 CD cord-022526-j9kg00qf 5361 8 years year NNS cord-022526-j9kg00qf 5361 9 old old JJ cord-022526-j9kg00qf 5361 10 and and CC cord-022526-j9kg00qf 5361 11 mainly mainly RB cord-022526-j9kg00qf 5361 12 affects affect VBZ cord-022526-j9kg00qf 5361 13 the the DT cord-022526-j9kg00qf 5361 14 mandible mandible NN cord-022526-j9kg00qf 5361 15 . . . cord-022526-j9kg00qf 5362 1 Ameloblastic Ameloblastic NNP cord-022526-j9kg00qf 5362 2 odontoma odontoma NNP cord-022526-j9kg00qf 5362 3 affects affect VBZ cord-022526-j9kg00qf 5362 4 younger young JJR cord-022526-j9kg00qf 5362 5 horses horse NNS cord-022526-j9kg00qf 5362 6 and and CC cord-022526-j9kg00qf 5362 7 usually usually RB cord-022526-j9kg00qf 5362 8 involves involve VBZ cord-022526-j9kg00qf 5362 9 the the DT cord-022526-j9kg00qf 5362 10 maxilla maxilla NN cord-022526-j9kg00qf 5362 11 . . . cord-022526-j9kg00qf 5363 1 Both both DT cord-022526-j9kg00qf 5363 2 are be VBP cord-022526-j9kg00qf 5363 3 benign benign JJ cord-022526-j9kg00qf 5363 4 but but CC cord-022526-j9kg00qf 5363 5 locally locally RB cord-022526-j9kg00qf 5363 6 invasive invasive JJ cord-022526-j9kg00qf 5363 7 . . . cord-022526-j9kg00qf 5364 1 Radiographs radiograph NNS cord-022526-j9kg00qf 5364 2 may may MD cord-022526-j9kg00qf 5364 3 distinguish distinguish VB cord-022526-j9kg00qf 5364 4 the the DT cord-022526-j9kg00qf 5364 5 difference difference NN cord-022526-j9kg00qf 5364 6 between between IN cord-022526-j9kg00qf 5364 7 an an DT cord-022526-j9kg00qf 5364 8 ameloblastoma ameloblastoma NN cord-022526-j9kg00qf 5364 9 ( ( -LRB- cord-022526-j9kg00qf 5364 10 radiolucent radiolucent JJ cord-022526-j9kg00qf 5364 11 lesion lesion NN cord-022526-j9kg00qf 5364 12 ) ) -RRB- cord-022526-j9kg00qf 5364 13 and and CC cord-022526-j9kg00qf 5364 14 ameloblastic ameloblastic NNP cord-022526-j9kg00qf 5364 15 odontoma odontoma NNP cord-022526-j9kg00qf 5364 16 ( ( -LRB- cord-022526-j9kg00qf 5364 17 radiolucent radiolucent JJ cord-022526-j9kg00qf 5364 18 lesion lesion NN cord-022526-j9kg00qf 5364 19 with with IN cord-022526-j9kg00qf 5364 20 partially partially RB cord-022526-j9kg00qf 5364 21 mineralized mineralized JJ cord-022526-j9kg00qf 5364 22 density density NN cord-022526-j9kg00qf 5364 23 ) ) -RRB- cord-022526-j9kg00qf 5364 24 . . . cord-022526-j9kg00qf 5365 1 The the DT cord-022526-j9kg00qf 5365 2 best good JJS cord-022526-j9kg00qf 5365 3 treatment treatment NN cord-022526-j9kg00qf 5365 4 option option NN cord-022526-j9kg00qf 5365 5 is be VBZ cord-022526-j9kg00qf 5365 6 surgical surgical JJ cord-022526-j9kg00qf 5365 7 resection resection NN cord-022526-j9kg00qf 5365 8 and and CC cord-022526-j9kg00qf 5365 9 radiation radiation NN cord-022526-j9kg00qf 5365 10 therapy therapy NN cord-022526-j9kg00qf 5365 11 regardless regardless RB cord-022526-j9kg00qf 5365 12 of of IN cord-022526-j9kg00qf 5365 13 the the DT cord-022526-j9kg00qf 5365 14 type type NN cord-022526-j9kg00qf 5365 15 . . . cord-022526-j9kg00qf 5366 1 48 48 CD cord-022526-j9kg00qf 5367 1 Juvenile juvenile JJ cord-022526-j9kg00qf 5367 2 mandibular mandibular NN cord-022526-j9kg00qf 5368 1 ossifying ossify VBG cord-022526-j9kg00qf 5368 2 fibroma fibroma NN cord-022526-j9kg00qf 5368 3 occurs occur VBZ cord-022526-j9kg00qf 5368 4 in in IN cord-022526-j9kg00qf 5368 5 the the DT cord-022526-j9kg00qf 5368 6 rostral rostral JJ cord-022526-j9kg00qf 5368 7 mandible mandible NN cord-022526-j9kg00qf 5368 8 of of IN cord-022526-j9kg00qf 5368 9 young young JJ cord-022526-j9kg00qf 5368 10 horses horse NNS cord-022526-j9kg00qf 5368 11 between between IN cord-022526-j9kg00qf 5368 12 the the DT cord-022526-j9kg00qf 5368 13 ages age NNS cord-022526-j9kg00qf 5368 14 of of IN cord-022526-j9kg00qf 5368 15 2 2 CD cord-022526-j9kg00qf 5368 16 months month NNS cord-022526-j9kg00qf 5368 17 and and CC cord-022526-j9kg00qf 5368 18 2 2 CD cord-022526-j9kg00qf 5368 19 years year NNS cord-022526-j9kg00qf 5368 20 . . . cord-022526-j9kg00qf 5369 1 The the DT cord-022526-j9kg00qf 5369 2 fibroma fibroma NN cord-022526-j9kg00qf 5369 3 may may MD cord-022526-j9kg00qf 5369 4 cause cause VB cord-022526-j9kg00qf 5369 5 significant significant JJ cord-022526-j9kg00qf 5369 6 distortion distortion NN cord-022526-j9kg00qf 5369 7 of of IN cord-022526-j9kg00qf 5369 8 the the DT cord-022526-j9kg00qf 5369 9 bone bone NN cord-022526-j9kg00qf 5369 10 . . . cord-022526-j9kg00qf 5370 1 With with IN cord-022526-j9kg00qf 5370 2 early early JJ cord-022526-j9kg00qf 5370 3 diagnosis diagnosis NN cord-022526-j9kg00qf 5370 4 and and CC cord-022526-j9kg00qf 5370 5 surgical surgical JJ cord-022526-j9kg00qf 5370 6 excision excision NN cord-022526-j9kg00qf 5370 7 of of IN cord-022526-j9kg00qf 5370 8 the the DT cord-022526-j9kg00qf 5370 9 mass mass NN cord-022526-j9kg00qf 5370 10 , , , cord-022526-j9kg00qf 5370 11 the the DT cord-022526-j9kg00qf 5370 12 horse horse NN cord-022526-j9kg00qf 5370 13 has have VBZ cord-022526-j9kg00qf 5370 14 a a DT cord-022526-j9kg00qf 5370 15 good good JJ cord-022526-j9kg00qf 5370 16 prognosis prognosis NN cord-022526-j9kg00qf 5370 17 . . . cord-022526-j9kg00qf 5371 1 75 75 CD cord-022526-j9kg00qf 5372 1 Melanomas melanoma NNS cord-022526-j9kg00qf 5372 2 , , , cord-022526-j9kg00qf 5372 3 sarcoids sarcoid NNS cord-022526-j9kg00qf 5372 4 , , , cord-022526-j9kg00qf 5372 5 and and CC cord-022526-j9kg00qf 5372 6 oral oral JJ cord-022526-j9kg00qf 5372 7 papilloma papilloma NN cord-022526-j9kg00qf 5372 8 occur occur VBP cord-022526-j9kg00qf 5372 9 on on IN cord-022526-j9kg00qf 5372 10 the the DT cord-022526-j9kg00qf 5372 11 mouth mouth NN cord-022526-j9kg00qf 5372 12 and and CC cord-022526-j9kg00qf 5372 13 lips lip NNS cord-022526-j9kg00qf 5372 14 . . . cord-022526-j9kg00qf 5373 1 Melanomas melanoma NNS cord-022526-j9kg00qf 5373 2 rarely rarely RB cord-022526-j9kg00qf 5373 3 metastasize metastasize VB cord-022526-j9kg00qf 5373 4 , , , cord-022526-j9kg00qf 5373 5 but but CC cord-022526-j9kg00qf 5373 6 they -PRON- PRP cord-022526-j9kg00qf 5373 7 commonly commonly RB cord-022526-j9kg00qf 5373 8 are be VBP cord-022526-j9kg00qf 5373 9 found find VBN cord-022526-j9kg00qf 5373 10 in in IN cord-022526-j9kg00qf 5373 11 the the DT cord-022526-j9kg00qf 5373 12 parotid parotid JJ cord-022526-j9kg00qf 5373 13 salivary salivary NN cord-022526-j9kg00qf 5373 14 glands gland NNS cord-022526-j9kg00qf 5373 15 and and CC cord-022526-j9kg00qf 5373 16 lymph lymph NN cord-022526-j9kg00qf 5373 17 nodes node NNS cord-022526-j9kg00qf 5373 18 . . . cord-022526-j9kg00qf 5374 1 Sarcoids sarcoid NNS cord-022526-j9kg00qf 5374 2 are be VBP cord-022526-j9kg00qf 5374 3 the the DT cord-022526-j9kg00qf 5374 4 most most RBS cord-022526-j9kg00qf 5374 5 common common JJ cord-022526-j9kg00qf 5374 6 skin skin NN cord-022526-j9kg00qf 5374 7 tumor tumor NN cord-022526-j9kg00qf 5374 8 that that WDT cord-022526-j9kg00qf 5374 9 can can MD cord-022526-j9kg00qf 5374 10 involve involve VB cord-022526-j9kg00qf 5374 11 the the DT cord-022526-j9kg00qf 5374 12 mouth mouth NN cord-022526-j9kg00qf 5374 13 . . . cord-022526-j9kg00qf 5375 1 Ulcerations ulceration NNS cord-022526-j9kg00qf 5375 2 of of IN cord-022526-j9kg00qf 5375 3 the the DT cord-022526-j9kg00qf 5375 4 buccal buccal JJ cord-022526-j9kg00qf 5375 5 mucosa mucosa NN cord-022526-j9kg00qf 5375 6 are be VBP cord-022526-j9kg00qf 5375 7 difficult difficult JJ cord-022526-j9kg00qf 5375 8 to to TO cord-022526-j9kg00qf 5375 9 treat treat VB cord-022526-j9kg00qf 5375 10 . . . cord-022526-j9kg00qf 5376 1 Intralesional Intralesional NNP cord-022526-j9kg00qf 5376 2 cisplatin cisplatin NN cord-022526-j9kg00qf 5376 3 , , , cord-022526-j9kg00qf 5376 4 cryosurgery cryosurgery NN cord-022526-j9kg00qf 5376 5 , , , cord-022526-j9kg00qf 5376 6 radiation radiation NN cord-022526-j9kg00qf 5376 7 , , , cord-022526-j9kg00qf 5376 8 and and CC cord-022526-j9kg00qf 5376 9 laser laser NN cord-022526-j9kg00qf 5376 10 excision excision NN cord-022526-j9kg00qf 5376 11 have have VBP cord-022526-j9kg00qf 5376 12 been be VBN cord-022526-j9kg00qf 5376 13 tried try VBN cord-022526-j9kg00qf 5376 14 with with IN cord-022526-j9kg00qf 5376 15 limited limited JJ cord-022526-j9kg00qf 5376 16 success success NN cord-022526-j9kg00qf 5376 17 . . . cord-022526-j9kg00qf 5377 1 5 5 CD cord-022526-j9kg00qf 5377 2 Equine equine JJ cord-022526-j9kg00qf 5377 3 papilloma papilloma NN cord-022526-j9kg00qf 5377 4 virus virus NN cord-022526-j9kg00qf 5377 5 is be VBZ cord-022526-j9kg00qf 5377 6 responsible responsible JJ cord-022526-j9kg00qf 5377 7 for for IN cord-022526-j9kg00qf 5377 8 the the DT cord-022526-j9kg00qf 5377 9 common common JJ cord-022526-j9kg00qf 5377 10 skin skin NN cord-022526-j9kg00qf 5377 11 wart wart NN cord-022526-j9kg00qf 5377 12 found find VBD cord-022526-j9kg00qf 5377 13 on on IN cord-022526-j9kg00qf 5377 14 the the DT cord-022526-j9kg00qf 5377 15 lips lip NNS cord-022526-j9kg00qf 5377 16 and and CC cord-022526-j9kg00qf 5377 17 muzzle muzzle NN cord-022526-j9kg00qf 5377 18 of of IN cord-022526-j9kg00qf 5377 19 young young JJ cord-022526-j9kg00qf 5377 20 horses horse NNS cord-022526-j9kg00qf 5377 21 . . . cord-022526-j9kg00qf 5378 1 These these DT cord-022526-j9kg00qf 5378 2 lesions lesion NNS cord-022526-j9kg00qf 5378 3 are be VBP cord-022526-j9kg00qf 5378 4 usually usually RB cord-022526-j9kg00qf 5378 5 selflimiting selflimite VBG cord-022526-j9kg00qf 5378 6 but but CC cord-022526-j9kg00qf 5378 7 may may MD cord-022526-j9kg00qf 5378 8 be be VB cord-022526-j9kg00qf 5378 9 removed remove VBN cord-022526-j9kg00qf 5378 10 successfully successfully RB cord-022526-j9kg00qf 5378 11 by by IN cord-022526-j9kg00qf 5378 12 cryosurgery cryosurgery NN cord-022526-j9kg00qf 5378 13 or or CC cord-022526-j9kg00qf 5378 14 excision excision NN cord-022526-j9kg00qf 5378 15 . . . cord-022526-j9kg00qf 5379 1 A a DT cord-022526-j9kg00qf 5379 2 number number NN cord-022526-j9kg00qf 5379 3 of of IN cord-022526-j9kg00qf 5379 4 detailed detailed JJ cord-022526-j9kg00qf 5379 5 and and CC cord-022526-j9kg00qf 5379 6 informative informative JJ cord-022526-j9kg00qf 5379 7 reviews review NNS cord-022526-j9kg00qf 5379 8 are be VBP cord-022526-j9kg00qf 5379 9 available available JJ cord-022526-j9kg00qf 5379 10 describing describe VBG cord-022526-j9kg00qf 5379 11 the the DT cord-022526-j9kg00qf 5379 12 anatomy anatomy NN cord-022526-j9kg00qf 5379 13 , , , cord-022526-j9kg00qf 5379 14 physiology physiology NN cord-022526-j9kg00qf 5379 15 , , , cord-022526-j9kg00qf 5379 16 and and CC cord-022526-j9kg00qf 5379 17 pathophysiology pathophysiology NN cord-022526-j9kg00qf 5379 18 of of IN cord-022526-j9kg00qf 5379 19 the the DT cord-022526-j9kg00qf 5379 20 equine equine JJ cord-022526-j9kg00qf 5379 21 peritoneum peritoneum NN cord-022526-j9kg00qf 5379 22 . . . cord-022526-j9kg00qf 5380 1 [ [ -LRB- cord-022526-j9kg00qf 5380 2 1 1 CD cord-022526-j9kg00qf 5380 3 ] ] -RRB- cord-022526-j9kg00qf 5380 4 [ [ -LRB- cord-022526-j9kg00qf 5380 5 2 2 CD cord-022526-j9kg00qf 5380 6 ] ] -RRB- cord-022526-j9kg00qf 5380 7 [ [ -LRB- cord-022526-j9kg00qf 5380 8 3 3 CD cord-022526-j9kg00qf 5380 9 ] ] -RRB- cord-022526-j9kg00qf 5380 10 [ [ -LRB- cord-022526-j9kg00qf 5380 11 4 4 CD cord-022526-j9kg00qf 5380 12 ] ] -RRB- cord-022526-j9kg00qf 5381 1 [ [ -LRB- cord-022526-j9kg00qf 5381 2 5 5 CD cord-022526-j9kg00qf 5381 3 ] ] -RRB- cord-022526-j9kg00qf 5382 1 The the DT cord-022526-j9kg00qf 5382 2 peritoneum peritoneum NN cord-022526-j9kg00qf 5382 3 consists consist VBZ cord-022526-j9kg00qf 5382 4 of of IN cord-022526-j9kg00qf 5382 5 a a DT cord-022526-j9kg00qf 5382 6 single single JJ cord-022526-j9kg00qf 5382 7 layer layer NN cord-022526-j9kg00qf 5382 8 of of IN cord-022526-j9kg00qf 5382 9 mesothelial mesothelial JJ cord-022526-j9kg00qf 5382 10 cells cell NNS cord-022526-j9kg00qf 5382 11 lining line VBG cord-022526-j9kg00qf 5382 12 the the DT cord-022526-j9kg00qf 5382 13 peritoneal peritoneal JJ cord-022526-j9kg00qf 5382 14 cavity cavity NN cord-022526-j9kg00qf 5382 15 and and CC cord-022526-j9kg00qf 5382 16 serosal serosal NN cord-022526-j9kg00qf 5382 17 surfaces surface NNS cord-022526-j9kg00qf 5382 18 of of IN cord-022526-j9kg00qf 5382 19 the the DT cord-022526-j9kg00qf 5382 20 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 5382 21 viscera viscera NNS cord-022526-j9kg00qf 5382 22 . . . cord-022526-j9kg00qf 5383 1 The the DT cord-022526-j9kg00qf 5383 2 mesothelial mesothelial JJ cord-022526-j9kg00qf 5383 3 lining lining NN cord-022526-j9kg00qf 5383 4 of of IN cord-022526-j9kg00qf 5383 5 the the DT cord-022526-j9kg00qf 5383 6 diaphragm diaphragm NN cord-022526-j9kg00qf 5383 7 , , , cord-022526-j9kg00qf 5383 8 abdominal abdominal JJ cord-022526-j9kg00qf 5383 9 walls wall NNS cord-022526-j9kg00qf 5383 10 , , , cord-022526-j9kg00qf 5383 11 and and CC cord-022526-j9kg00qf 5383 12 pelvic pelvic JJ cord-022526-j9kg00qf 5383 13 cavity cavity NN cord-022526-j9kg00qf 5383 14 is be VBZ cord-022526-j9kg00qf 5383 15 termed term VBN cord-022526-j9kg00qf 5383 16 parietal parietal JJ cord-022526-j9kg00qf 5383 17 peritoneum peritoneum NN cord-022526-j9kg00qf 5383 18 . . . cord-022526-j9kg00qf 5384 1 The the DT cord-022526-j9kg00qf 5384 2 visceral visceral JJ cord-022526-j9kg00qf 5384 3 peritoneum peritoneum NN cord-022526-j9kg00qf 5384 4 includes include VBZ cord-022526-j9kg00qf 5384 5 the the DT cord-022526-j9kg00qf 5384 6 serosal serosal NN cord-022526-j9kg00qf 5384 7 surfaces surface NNS cord-022526-j9kg00qf 5384 8 of of IN cord-022526-j9kg00qf 5384 9 the the DT cord-022526-j9kg00qf 5384 10 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 5384 11 organs organ NNS cord-022526-j9kg00qf 5384 12 . . . cord-022526-j9kg00qf 5385 1 The the DT cord-022526-j9kg00qf 5385 2 parietal parietal JJ cord-022526-j9kg00qf 5385 3 and and CC cord-022526-j9kg00qf 5385 4 visceral visceral JJ cord-022526-j9kg00qf 5385 5 portions portion NNS cord-022526-j9kg00qf 5385 6 of of IN cord-022526-j9kg00qf 5385 7 the the DT cord-022526-j9kg00qf 5385 8 peritoneum peritoneum NN cord-022526-j9kg00qf 5385 9 are be VBP cord-022526-j9kg00qf 5385 10 contiguous contiguous JJ cord-022526-j9kg00qf 5385 11 with with IN cord-022526-j9kg00qf 5385 12 each each DT cord-022526-j9kg00qf 5385 13 other other JJ cord-022526-j9kg00qf 5385 14 through through IN cord-022526-j9kg00qf 5385 15 the the DT cord-022526-j9kg00qf 5385 16 omentum omentum NN cord-022526-j9kg00qf 5385 17 , , , cord-022526-j9kg00qf 5385 18 mesenteries mesentery NNS cord-022526-j9kg00qf 5385 19 , , , cord-022526-j9kg00qf 5385 20 and and CC cord-022526-j9kg00qf 5385 21 ligaments ligament NNS cord-022526-j9kg00qf 5385 22 . . . cord-022526-j9kg00qf 5386 1 Caudally caudally RB cord-022526-j9kg00qf 5386 2 , , , cord-022526-j9kg00qf 5386 3 the the DT cord-022526-j9kg00qf 5386 4 peritoneum peritoneum NN cord-022526-j9kg00qf 5386 5 reflects reflect VBZ cord-022526-j9kg00qf 5386 6 over over IN cord-022526-j9kg00qf 5386 7 the the DT cord-022526-j9kg00qf 5386 8 surfaces surface NNS cord-022526-j9kg00qf 5386 9 of of IN cord-022526-j9kg00qf 5386 10 the the DT cord-022526-j9kg00qf 5386 11 pelvic pelvic JJ cord-022526-j9kg00qf 5386 12 organs organ NNS cord-022526-j9kg00qf 5386 13 ( ( -LRB- cord-022526-j9kg00qf 5386 14 portions portion NNS cord-022526-j9kg00qf 5386 15 of of IN cord-022526-j9kg00qf 5386 16 the the DT cord-022526-j9kg00qf 5386 17 urogenital urogenital JJ cord-022526-j9kg00qf 5386 18 tract tract NN cord-022526-j9kg00qf 5386 19 and and CC cord-022526-j9kg00qf 5386 20 rectum rectum NN cord-022526-j9kg00qf 5386 21 ) ) -RRB- cord-022526-j9kg00qf 5386 22 , , , cord-022526-j9kg00qf 5386 23 excluding exclude VBG cord-022526-j9kg00qf 5386 24 them -PRON- PRP cord-022526-j9kg00qf 5386 25 from from IN cord-022526-j9kg00qf 5386 26 the the DT cord-022526-j9kg00qf 5386 27 peritoneal peritoneal JJ cord-022526-j9kg00qf 5386 28 space space NN cord-022526-j9kg00qf 5386 29 , , , cord-022526-j9kg00qf 5386 30 and and CC cord-022526-j9kg00qf 5386 31 thus thus RB cord-022526-j9kg00qf 5386 32 much much JJ cord-022526-j9kg00qf 5386 33 of of IN cord-022526-j9kg00qf 5386 34 the the DT cord-022526-j9kg00qf 5386 35 pelvic pelvic JJ cord-022526-j9kg00qf 5386 36 cavity cavity NN cord-022526-j9kg00qf 5386 37 and and CC cord-022526-j9kg00qf 5386 38 contents content NNS cord-022526-j9kg00qf 5386 39 are be VBP cord-022526-j9kg00qf 5386 40 described describe VBN cord-022526-j9kg00qf 5386 41 as as IN cord-022526-j9kg00qf 5386 42 retroperitoneal retroperitoneal JJ cord-022526-j9kg00qf 5386 43 . . . cord-022526-j9kg00qf 5387 1 The the DT cord-022526-j9kg00qf 5387 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5387 3 space space NN cord-022526-j9kg00qf 5387 4 communicates communicate VBZ cord-022526-j9kg00qf 5387 5 with with IN cord-022526-j9kg00qf 5387 6 the the DT cord-022526-j9kg00qf 5387 7 lumen lumen NN cord-022526-j9kg00qf 5387 8 of of IN cord-022526-j9kg00qf 5387 9 the the DT cord-022526-j9kg00qf 5387 10 uterus uterus NN cord-022526-j9kg00qf 5387 11 ( ( -LRB- cord-022526-j9kg00qf 5387 12 and and CC cord-022526-j9kg00qf 5387 13 thus thus RB cord-022526-j9kg00qf 5387 14 the the DT cord-022526-j9kg00qf 5387 15 external external JJ cord-022526-j9kg00qf 5387 16 environment environment NN cord-022526-j9kg00qf 5387 17 ) ) -RRB- cord-022526-j9kg00qf 5387 18 via via IN cord-022526-j9kg00qf 5387 19 the the DT cord-022526-j9kg00qf 5387 20 fallopian fallopian JJ cord-022526-j9kg00qf 5387 21 tubes tube NNS cord-022526-j9kg00qf 5387 22 in in IN cord-022526-j9kg00qf 5387 23 females female NNS cord-022526-j9kg00qf 5387 24 . . . cord-022526-j9kg00qf 5388 1 In in IN cord-022526-j9kg00qf 5388 2 males male NNS cord-022526-j9kg00qf 5388 3 the the DT cord-022526-j9kg00qf 5388 4 peritoneum peritoneum NN cord-022526-j9kg00qf 5388 5 forms form VBZ cord-022526-j9kg00qf 5388 6 a a DT cord-022526-j9kg00qf 5388 7 true true JJ cord-022526-j9kg00qf 5388 8 blind blind JJ cord-022526-j9kg00qf 5388 9 sac sac NN cord-022526-j9kg00qf 5388 10 . . . cord-022526-j9kg00qf 5389 1 The the DT cord-022526-j9kg00qf 5389 2 vascular vascular JJ cord-022526-j9kg00qf 5389 3 supply supply NN cord-022526-j9kg00qf 5389 4 and and CC cord-022526-j9kg00qf 5389 5 nervous nervous JJ cord-022526-j9kg00qf 5389 6 innervation innervation NN cord-022526-j9kg00qf 5389 7 of of IN cord-022526-j9kg00qf 5389 8 the the DT cord-022526-j9kg00qf 5389 9 visceral visceral JJ cord-022526-j9kg00qf 5389 10 peritoneum peritoneum NNS cord-022526-j9kg00qf 5389 11 are be VBP cord-022526-j9kg00qf 5389 12 supplied supply VBN cord-022526-j9kg00qf 5389 13 by by IN cord-022526-j9kg00qf 5389 14 the the DT cord-022526-j9kg00qf 5389 15 splanchnic splanchnic JJ cord-022526-j9kg00qf 5389 16 vessels vessel NNS cord-022526-j9kg00qf 5389 17 and and CC cord-022526-j9kg00qf 5389 18 visceral visceral JJ cord-022526-j9kg00qf 5389 19 autonomic autonomic JJ cord-022526-j9kg00qf 5389 20 nerves nerve NNS cord-022526-j9kg00qf 5389 21 , , , cord-022526-j9kg00qf 5389 22 respectively respectively RB cord-022526-j9kg00qf 5389 23 . . . cord-022526-j9kg00qf 5390 1 Branches branch NNS cord-022526-j9kg00qf 5390 2 of of IN cord-022526-j9kg00qf 5390 3 the the DT cord-022526-j9kg00qf 5390 4 intercostal intercostal JJ cord-022526-j9kg00qf 5390 5 , , , cord-022526-j9kg00qf 5390 6 lumbar lumbar NN cord-022526-j9kg00qf 5390 7 , , , cord-022526-j9kg00qf 5390 8 and and CC cord-022526-j9kg00qf 5390 9 iliac iliac NN cord-022526-j9kg00qf 5390 10 arteries artery NNS cord-022526-j9kg00qf 5390 11 supply supply VBP cord-022526-j9kg00qf 5390 12 the the DT cord-022526-j9kg00qf 5390 13 parietal parietal JJ cord-022526-j9kg00qf 5390 14 peritoneum peritoneum NN cord-022526-j9kg00qf 5390 15 , , , cord-022526-j9kg00qf 5390 16 and and CC cord-022526-j9kg00qf 5390 17 the the DT cord-022526-j9kg00qf 5390 18 phrenic phrenic JJ cord-022526-j9kg00qf 5390 19 and and CC cord-022526-j9kg00qf 5390 20 intercostal intercostal JJ cord-022526-j9kg00qf 5390 21 nerves nerve NNS cord-022526-j9kg00qf 5390 22 provide provide VBP cord-022526-j9kg00qf 5390 23 nervous nervous JJ cord-022526-j9kg00qf 5390 24 innervation innervation NN cord-022526-j9kg00qf 5390 25 . . . cord-022526-j9kg00qf 5391 1 The the DT cord-022526-j9kg00qf 5391 2 clinical clinical JJ cord-022526-j9kg00qf 5391 3 relevance relevance NN cord-022526-j9kg00qf 5391 4 is be VBZ cord-022526-j9kg00qf 5391 5 that that DT cord-022526-j9kg00qf 5391 6 inflammation inflammation NN cord-022526-j9kg00qf 5391 7 of of IN cord-022526-j9kg00qf 5391 8 the the DT cord-022526-j9kg00qf 5391 9 parietal parietal JJ cord-022526-j9kg00qf 5391 10 peritoneum peritoneum NN cord-022526-j9kg00qf 5391 11 is be VBZ cord-022526-j9kg00qf 5391 12 perceived perceive VBN cord-022526-j9kg00qf 5391 13 as as IN cord-022526-j9kg00qf 5391 14 somatic somatic JJ cord-022526-j9kg00qf 5391 15 pain pain NN cord-022526-j9kg00qf 5391 16 , , , cord-022526-j9kg00qf 5391 17 resulting result VBG cord-022526-j9kg00qf 5391 18 in in IN cord-022526-j9kg00qf 5391 19 a a DT cord-022526-j9kg00qf 5391 20 splinted splint VBN cord-022526-j9kg00qf 5391 21 abdominal abdominal JJ cord-022526-j9kg00qf 5391 22 wall wall NN cord-022526-j9kg00qf 5391 23 , , , cord-022526-j9kg00qf 5391 24 pain pain NN cord-022526-j9kg00qf 5391 25 on on IN cord-022526-j9kg00qf 5391 26 external external JJ cord-022526-j9kg00qf 5391 27 palpation palpation NN cord-022526-j9kg00qf 5391 28 , , , cord-022526-j9kg00qf 5391 29 and and CC cord-022526-j9kg00qf 5391 30 reluctance reluctance NN cord-022526-j9kg00qf 5391 31 to to TO cord-022526-j9kg00qf 5391 32 move move VB cord-022526-j9kg00qf 5391 33 . . . cord-022526-j9kg00qf 5392 1 Visceral visceral JJ cord-022526-j9kg00qf 5392 2 pain pain NN cord-022526-j9kg00qf 5392 3 is be VBZ cord-022526-j9kg00qf 5392 4 mediated mediate VBN cord-022526-j9kg00qf 5392 5 by by IN cord-022526-j9kg00qf 5392 6 small small JJ cord-022526-j9kg00qf 5392 7 type type NN cord-022526-j9kg00qf 5392 8 C c NN cord-022526-j9kg00qf 5392 9 sensory sensory JJ cord-022526-j9kg00qf 5392 10 fibers fiber NNS cord-022526-j9kg00qf 5392 11 , , , cord-022526-j9kg00qf 5392 12 which which WDT cord-022526-j9kg00qf 5392 13 are be VBP cord-022526-j9kg00qf 5392 14 believed believe VBN cord-022526-j9kg00qf 5392 15 to to TO cord-022526-j9kg00qf 5392 16 be be VB cord-022526-j9kg00qf 5392 17 stimulated stimulate VBN cord-022526-j9kg00qf 5392 18 by by IN cord-022526-j9kg00qf 5392 19 bowel bowel NN cord-022526-j9kg00qf 5392 20 distention distention NN cord-022526-j9kg00qf 5392 21 , , , cord-022526-j9kg00qf 5392 22 smooth smooth JJ cord-022526-j9kg00qf 5392 23 muscle muscle NN cord-022526-j9kg00qf 5392 24 spasms spasm NNS cord-022526-j9kg00qf 5392 25 , , , cord-022526-j9kg00qf 5392 26 tension tension NN cord-022526-j9kg00qf 5392 27 on on IN cord-022526-j9kg00qf 5392 28 the the DT cord-022526-j9kg00qf 5392 29 mesentery mesentery NN cord-022526-j9kg00qf 5392 30 , , , cord-022526-j9kg00qf 5392 31 and and CC cord-022526-j9kg00qf 5392 32 ischemia ischemia NN cord-022526-j9kg00qf 5392 33 . . . cord-022526-j9kg00qf 5393 1 The the DT cord-022526-j9kg00qf 5393 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5393 3 lining lining NN cord-022526-j9kg00qf 5393 4 functions function NNS cord-022526-j9kg00qf 5393 5 as as IN cord-022526-j9kg00qf 5393 6 a a DT cord-022526-j9kg00qf 5393 7 semipermeable semipermeable JJ cord-022526-j9kg00qf 5393 8 barrier barrier NN cord-022526-j9kg00qf 5393 9 to to IN cord-022526-j9kg00qf 5393 10 the the DT cord-022526-j9kg00qf 5393 11 diffusion diffusion NN cord-022526-j9kg00qf 5393 12 of of IN cord-022526-j9kg00qf 5393 13 water water NN cord-022526-j9kg00qf 5393 14 and and CC cord-022526-j9kg00qf 5393 15 low low JJ cord-022526-j9kg00qf 5393 16 - - HYPH cord-022526-j9kg00qf 5393 17 molecular molecular JJ cord-022526-j9kg00qf 5393 18 weight weight NN cord-022526-j9kg00qf 5393 19 solutes solute NNS cord-022526-j9kg00qf 5393 20 between between IN cord-022526-j9kg00qf 5393 21 the the DT cord-022526-j9kg00qf 5393 22 blood blood NN cord-022526-j9kg00qf 5393 23 and and CC cord-022526-j9kg00qf 5393 24 the the DT cord-022526-j9kg00qf 5393 25 abdominal abdominal JJ cord-022526-j9kg00qf 5393 26 cavity cavity NN cord-022526-j9kg00qf 5393 27 . . . cord-022526-j9kg00qf 5394 1 1 1 LS cord-022526-j9kg00qf 5395 1 The the DT cord-022526-j9kg00qf 5395 2 peritoneum peritoneum NN cord-022526-j9kg00qf 5395 3 secretes secrete VBZ cord-022526-j9kg00qf 5395 4 a a DT cord-022526-j9kg00qf 5395 5 serous serous JJ cord-022526-j9kg00qf 5395 6 fluid fluid NN cord-022526-j9kg00qf 5395 7 that that WDT cord-022526-j9kg00qf 5395 8 lubricates lubricate VBZ cord-022526-j9kg00qf 5395 9 the the DT cord-022526-j9kg00qf 5395 10 abdominal abdominal JJ cord-022526-j9kg00qf 5395 11 cavity cavity NN cord-022526-j9kg00qf 5395 12 , , , cord-022526-j9kg00qf 5395 13 inhibits inhibit VBZ cord-022526-j9kg00qf 5395 14 adhesion adhesion NN cord-022526-j9kg00qf 5395 15 formation formation NN cord-022526-j9kg00qf 5395 16 , , , cord-022526-j9kg00qf 5395 17 and and CC cord-022526-j9kg00qf 5395 18 has have VBZ cord-022526-j9kg00qf 5395 19 minor minor JJ cord-022526-j9kg00qf 5395 20 antibacterial antibacterial JJ cord-022526-j9kg00qf 5395 21 properties property NNS cord-022526-j9kg00qf 5395 22 . . . cord-022526-j9kg00qf 5396 1 1,2 1,2 LS cord-022526-j9kg00qf 5396 2 Macrophages macrophage NNS cord-022526-j9kg00qf 5396 3 , , , cord-022526-j9kg00qf 5396 4 mast mast NN cord-022526-j9kg00qf 5396 5 cells cell NNS cord-022526-j9kg00qf 5396 6 , , , cord-022526-j9kg00qf 5396 7 mesothelial mesothelial JJ cord-022526-j9kg00qf 5396 8 cells cell NNS cord-022526-j9kg00qf 5396 9 , , , cord-022526-j9kg00qf 5396 10 and and CC cord-022526-j9kg00qf 5396 11 lymphocytes lymphocyte NNS cord-022526-j9kg00qf 5396 12 provide provide VBP cord-022526-j9kg00qf 5396 13 immune immune JJ cord-022526-j9kg00qf 5396 14 function function NN cord-022526-j9kg00qf 5396 15 within within IN cord-022526-j9kg00qf 5396 16 the the DT cord-022526-j9kg00qf 5396 17 peritoneum peritoneum NN cord-022526-j9kg00qf 5396 18 . . . cord-022526-j9kg00qf 5397 1 2,3 2,3 LS cord-022526-j9kg00qf 5398 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5398 2 macrophages macrophage NNS cord-022526-j9kg00qf 5398 3 impart impart VBP cord-022526-j9kg00qf 5398 4 antibacterial antibacterial JJ cord-022526-j9kg00qf 5398 5 activity activity NN cord-022526-j9kg00qf 5398 6 via via IN cord-022526-j9kg00qf 5398 7 complement complement JJ cord-022526-j9kg00qf 5398 8 receptors receptor NNS cord-022526-j9kg00qf 5398 9 , , , cord-022526-j9kg00qf 5398 10 phagocytic phagocytic JJ cord-022526-j9kg00qf 5398 11 activity activity NN cord-022526-j9kg00qf 5398 12 , , , cord-022526-j9kg00qf 5398 13 interaction interaction NN cord-022526-j9kg00qf 5398 14 with with IN cord-022526-j9kg00qf 5398 15 T t NN cord-022526-j9kg00qf 5398 16 lymphocytes lymphocyte NNS cord-022526-j9kg00qf 5398 17 , , , cord-022526-j9kg00qf 5398 18 neutrophil neutrophil NN cord-022526-j9kg00qf 5398 19 chemotaxis chemotaxis NN cord-022526-j9kg00qf 5398 20 , , , cord-022526-j9kg00qf 5398 21 and and CC cord-022526-j9kg00qf 5398 22 fibroblast fibroblast NN cord-022526-j9kg00qf 5398 23 activation activation NN cord-022526-j9kg00qf 5398 24 . . . cord-022526-j9kg00qf 5399 1 The the DT cord-022526-j9kg00qf 5399 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5399 3 surface surface NN cord-022526-j9kg00qf 5399 4 maintains maintain VBZ cord-022526-j9kg00qf 5399 5 a a DT cord-022526-j9kg00qf 5399 6 high high JJ cord-022526-j9kg00qf 5399 7 level level NN cord-022526-j9kg00qf 5399 8 of of IN cord-022526-j9kg00qf 5399 9 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 5399 10 activity activity NN cord-022526-j9kg00qf 5399 11 through through IN cord-022526-j9kg00qf 5399 12 the the DT cord-022526-j9kg00qf 5399 13 production production NN cord-022526-j9kg00qf 5399 14 of of IN cord-022526-j9kg00qf 5399 15 plasminogen plasminogen NN cord-022526-j9kg00qf 5399 16 activators activator NNS cord-022526-j9kg00qf 5399 17 by by IN cord-022526-j9kg00qf 5399 18 mesothelial mesothelial JJ cord-022526-j9kg00qf 5399 19 cells cell NNS cord-022526-j9kg00qf 5399 20 . . . cord-022526-j9kg00qf 5400 1 This this DT cord-022526-j9kg00qf 5400 2 function function NN cord-022526-j9kg00qf 5400 3 , , , cord-022526-j9kg00qf 5400 4 together together RB cord-022526-j9kg00qf 5400 5 with with IN cord-022526-j9kg00qf 5400 6 the the DT cord-022526-j9kg00qf 5400 7 lubricant lubricant NN cord-022526-j9kg00qf 5400 8 properties property NNS cord-022526-j9kg00qf 5400 9 of of IN cord-022526-j9kg00qf 5400 10 the the DT cord-022526-j9kg00qf 5400 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 5400 12 fluid fluid NN cord-022526-j9kg00qf 5400 13 , , , cord-022526-j9kg00qf 5400 14 helps help VBZ cord-022526-j9kg00qf 5400 15 to to TO cord-022526-j9kg00qf 5400 16 maintain maintain VB cord-022526-j9kg00qf 5400 17 gliding gliding NN cord-022526-j9kg00qf 5400 18 surfaces surface NNS cord-022526-j9kg00qf 5400 19 within within IN cord-022526-j9kg00qf 5400 20 the the DT cord-022526-j9kg00qf 5400 21 peritoneum peritoneum NN cord-022526-j9kg00qf 5400 22 and and CC cord-022526-j9kg00qf 5400 23 prevent prevent VB cord-022526-j9kg00qf 5400 24 adhesion adhesion NN cord-022526-j9kg00qf 5400 25 formation formation NN cord-022526-j9kg00qf 5400 26 . . . cord-022526-j9kg00qf 5401 1 In in IN cord-022526-j9kg00qf 5401 2 quadrupeds quadruped NNS cord-022526-j9kg00qf 5401 3 , , , cord-022526-j9kg00qf 5401 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5401 5 fluid fluid NN cord-022526-j9kg00qf 5401 6 produced produce VBN cord-022526-j9kg00qf 5401 7 by by IN cord-022526-j9kg00qf 5401 8 the the DT cord-022526-j9kg00qf 5401 9 mesothelium mesothelium NN cord-022526-j9kg00qf 5401 10 tends tend VBZ cord-022526-j9kg00qf 5401 11 to to TO cord-022526-j9kg00qf 5401 12 move move VB cord-022526-j9kg00qf 5401 13 ventrally ventrally RB cord-022526-j9kg00qf 5401 14 and and CC cord-022526-j9kg00qf 5401 15 cranially cranially RB cord-022526-j9kg00qf 5401 16 , , , cord-022526-j9kg00qf 5401 17 aided aid VBN cord-022526-j9kg00qf 5401 18 largely largely RB cord-022526-j9kg00qf 5401 19 by by IN cord-022526-j9kg00qf 5401 20 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5401 21 movement movement NN cord-022526-j9kg00qf 5401 22 . . . cord-022526-j9kg00qf 5402 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5402 2 fluid fluid NN cord-022526-j9kg00qf 5402 3 , , , cord-022526-j9kg00qf 5402 4 waste waste NN cord-022526-j9kg00qf 5402 5 products product NNS cord-022526-j9kg00qf 5402 6 , , , cord-022526-j9kg00qf 5402 7 and and CC cord-022526-j9kg00qf 5402 8 foreign foreign JJ cord-022526-j9kg00qf 5402 9 material material NN cord-022526-j9kg00qf 5402 10 ( ( -LRB- cord-022526-j9kg00qf 5402 11 including include VBG cord-022526-j9kg00qf 5402 12 bacteria bacteria NNS cord-022526-j9kg00qf 5402 13 ) ) -RRB- cord-022526-j9kg00qf 5402 14 exit exit VB cord-022526-j9kg00qf 5402 15 the the DT cord-022526-j9kg00qf 5402 16 peritoneal peritoneal JJ cord-022526-j9kg00qf 5402 17 cavity cavity NN cord-022526-j9kg00qf 5402 18 to to TO cord-022526-j9kg00qf 5402 19 enter enter VB cord-022526-j9kg00qf 5402 20 the the DT cord-022526-j9kg00qf 5402 21 lymphatic lymphatic JJ cord-022526-j9kg00qf 5402 22 system system NN cord-022526-j9kg00qf 5402 23 through through IN cord-022526-j9kg00qf 5402 24 diffusely diffusely RB cord-022526-j9kg00qf 5402 25 distributed distribute VBN cord-022526-j9kg00qf 5402 26 subendothelial subendothelial JJ cord-022526-j9kg00qf 5402 27 pores pore NNS cord-022526-j9kg00qf 5402 28 or or CC cord-022526-j9kg00qf 5402 29 via via IN cord-022526-j9kg00qf 5402 30 the the DT cord-022526-j9kg00qf 5402 31 large large JJ cord-022526-j9kg00qf 5402 32 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5402 33 stomata stoma NNS cord-022526-j9kg00qf 5402 34 , , , cord-022526-j9kg00qf 5402 35 depending depend VBG cord-022526-j9kg00qf 5402 36 on on IN cord-022526-j9kg00qf 5402 37 particle particle NN cord-022526-j9kg00qf 5402 38 size size NN cord-022526-j9kg00qf 5402 39 . . . cord-022526-j9kg00qf 5403 1 Large large JJ cord-022526-j9kg00qf 5403 2 molecules molecule NNS cord-022526-j9kg00qf 5403 3 and and CC cord-022526-j9kg00qf 5403 4 particles particle NNS cord-022526-j9kg00qf 5404 1 greater great JJR cord-022526-j9kg00qf 5404 2 than than IN cord-022526-j9kg00qf 5404 3 approximately approximately RB cord-022526-j9kg00qf 5404 4 40,000 40,000 CD cord-022526-j9kg00qf 5404 5 MW MW NNP cord-022526-j9kg00qf 5404 6 ( ( -LRB- cord-022526-j9kg00qf 5404 7 such such JJ cord-022526-j9kg00qf 5404 8 as as IN cord-022526-j9kg00qf 5404 9 bacteria bacteria NNS cord-022526-j9kg00qf 5404 10 ) ) -RRB- cord-022526-j9kg00qf 5404 11 exit exit VBP cord-022526-j9kg00qf 5404 12 through through IN cord-022526-j9kg00qf 5404 13 the the DT cord-022526-j9kg00qf 5404 14 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5404 15 stomata stoma NNS cord-022526-j9kg00qf 5404 16 and and CC cord-022526-j9kg00qf 5404 17 ultimately ultimately RB cord-022526-j9kg00qf 5404 18 enter enter VBP cord-022526-j9kg00qf 5404 19 the the DT cord-022526-j9kg00qf 5404 20 thoracic thoracic JJ cord-022526-j9kg00qf 5404 21 duct duct NN cord-022526-j9kg00qf 5404 22 . . . cord-022526-j9kg00qf 5405 1 Peritonitis peritonitis NN cord-022526-j9kg00qf 5405 2 is be VBZ cord-022526-j9kg00qf 5405 3 inflammation inflammation NN cord-022526-j9kg00qf 5405 4 of of IN cord-022526-j9kg00qf 5405 5 the the DT cord-022526-j9kg00qf 5405 6 mesothelial mesothelial JJ cord-022526-j9kg00qf 5405 7 lining lining NN cord-022526-j9kg00qf 5405 8 of of IN cord-022526-j9kg00qf 5405 9 the the DT cord-022526-j9kg00qf 5405 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5405 11 cavity cavity NN cord-022526-j9kg00qf 5405 12 and and CC cord-022526-j9kg00qf 5405 13 is be VBZ cord-022526-j9kg00qf 5405 14 characterized characterize VBN cord-022526-j9kg00qf 5405 15 by by IN cord-022526-j9kg00qf 5405 16 desquamation desquamation NN cord-022526-j9kg00qf 5405 17 and and CC cord-022526-j9kg00qf 5405 18 transformation transformation NN cord-022526-j9kg00qf 5405 19 of of IN cord-022526-j9kg00qf 5405 20 mesothelial mesothelial JJ cord-022526-j9kg00qf 5405 21 cells cell NNS cord-022526-j9kg00qf 5405 22 ; ; : cord-022526-j9kg00qf 5405 23 chemotaxis chemotaxis NN cord-022526-j9kg00qf 5405 24 of of IN cord-022526-j9kg00qf 5405 25 neutrophils neutrophil NNS cord-022526-j9kg00qf 5405 26 ; ; : cord-022526-j9kg00qf 5405 27 release release NN cord-022526-j9kg00qf 5405 28 of of IN cord-022526-j9kg00qf 5405 29 several several JJ cord-022526-j9kg00qf 5405 30 soluble soluble JJ cord-022526-j9kg00qf 5405 31 mediators mediator NNS cord-022526-j9kg00qf 5405 32 of of IN cord-022526-j9kg00qf 5405 33 inflammation inflammation NN cord-022526-j9kg00qf 5405 34 ; ; : cord-022526-j9kg00qf 5405 35 exudation exudation NN cord-022526-j9kg00qf 5405 36 of of IN cord-022526-j9kg00qf 5405 37 serum serum NN cord-022526-j9kg00qf 5405 38 , , , cord-022526-j9kg00qf 5405 39 fibrin fibrin NN cord-022526-j9kg00qf 5405 40 , , , cord-022526-j9kg00qf 5405 41 and and CC cord-022526-j9kg00qf 5405 42 protein protein NN cord-022526-j9kg00qf 5405 43 into into IN cord-022526-j9kg00qf 5405 44 the the DT cord-022526-j9kg00qf 5405 45 peritoneal peritoneal JJ cord-022526-j9kg00qf 5405 46 cavity cavity NN cord-022526-j9kg00qf 5405 47 ; ; : cord-022526-j9kg00qf 5405 48 and and CC cord-022526-j9kg00qf 5405 49 depression depression NN cord-022526-j9kg00qf 5405 50 of of IN cord-022526-j9kg00qf 5405 51 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 5405 52 activity activity NN cord-022526-j9kg00qf 5405 53 . . . cord-022526-j9kg00qf 5406 1 Peritonitis peritonitis NN cord-022526-j9kg00qf 5406 2 occurs occur VBZ cord-022526-j9kg00qf 5406 3 in in IN cord-022526-j9kg00qf 5406 4 association association NN cord-022526-j9kg00qf 5406 5 with with IN cord-022526-j9kg00qf 5406 6 a a DT cord-022526-j9kg00qf 5406 7 variety variety NN cord-022526-j9kg00qf 5406 8 of of IN cord-022526-j9kg00qf 5406 9 disorders disorder NNS cord-022526-j9kg00qf 5406 10 that that WDT cord-022526-j9kg00qf 5406 11 result result VBP cord-022526-j9kg00qf 5406 12 in in IN cord-022526-j9kg00qf 5406 13 mechanical mechanical JJ cord-022526-j9kg00qf 5406 14 , , , cord-022526-j9kg00qf 5406 15 chemical chemical NN cord-022526-j9kg00qf 5406 16 , , , cord-022526-j9kg00qf 5406 17 or or CC cord-022526-j9kg00qf 5406 18 infectious infectious JJ cord-022526-j9kg00qf 5406 19 insult insult NN cord-022526-j9kg00qf 5406 20 to to IN cord-022526-j9kg00qf 5406 21 the the DT cord-022526-j9kg00qf 5406 22 peritoneal peritoneal JJ cord-022526-j9kg00qf 5406 23 lining lining NN cord-022526-j9kg00qf 5406 24 . . . cord-022526-j9kg00qf 5407 1 [ [ -LRB- cord-022526-j9kg00qf 5407 2 1 1 CD cord-022526-j9kg00qf 5407 3 ] ] -RRB- cord-022526-j9kg00qf 5407 4 [ [ -LRB- cord-022526-j9kg00qf 5407 5 2 2 CD cord-022526-j9kg00qf 5407 6 ] ] -RRB- cord-022526-j9kg00qf 5407 7 [ [ -LRB- cord-022526-j9kg00qf 5407 8 3 3 CD cord-022526-j9kg00qf 5407 9 ] ] -RRB- cord-022526-j9kg00qf 5407 10 [ [ -LRB- cord-022526-j9kg00qf 5407 11 4 4 CD cord-022526-j9kg00qf 5407 12 ] ] -RRB- cord-022526-j9kg00qf 5408 1 Any any DT cord-022526-j9kg00qf 5408 2 process process NN cord-022526-j9kg00qf 5408 3 resulting result VBG cord-022526-j9kg00qf 5408 4 in in IN cord-022526-j9kg00qf 5408 5 disruption disruption NN cord-022526-j9kg00qf 5408 6 or or CC cord-022526-j9kg00qf 5408 7 irritation irritation NN cord-022526-j9kg00qf 5408 8 of of IN cord-022526-j9kg00qf 5408 9 the the DT cord-022526-j9kg00qf 5408 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5408 11 lining lining NN cord-022526-j9kg00qf 5408 12 , , , cord-022526-j9kg00qf 5408 13 inflammation inflammation NN cord-022526-j9kg00qf 5408 14 or or CC cord-022526-j9kg00qf 5408 15 infection infection NN cord-022526-j9kg00qf 5408 16 of of IN cord-022526-j9kg00qf 5408 17 abdominal abdominal JJ cord-022526-j9kg00qf 5408 18 organs organ NNS cord-022526-j9kg00qf 5408 19 , , , cord-022526-j9kg00qf 5408 20 or or CC cord-022526-j9kg00qf 5408 21 compromise compromise NN cord-022526-j9kg00qf 5408 22 of of IN cord-022526-j9kg00qf 5408 23 the the DT cord-022526-j9kg00qf 5408 24 intestinal intestinal JJ cord-022526-j9kg00qf 5408 25 wall wall NN cord-022526-j9kg00qf 5408 26 can can MD cord-022526-j9kg00qf 5408 27 result result VB cord-022526-j9kg00qf 5408 28 in in IN cord-022526-j9kg00qf 5408 29 peritonitis peritonitis NN cord-022526-j9kg00qf 5408 30 ( ( -LRB- cord-022526-j9kg00qf 5408 31 Box Box NNP cord-022526-j9kg00qf 5408 32 13.17 13.17 CD cord-022526-j9kg00qf 5408 33 - - SYM cord-022526-j9kg00qf 5408 34 1 1 CD cord-022526-j9kg00qf 5408 35 ) ) -RRB- cord-022526-j9kg00qf 5408 36 . . . cord-022526-j9kg00qf 5409 1 Common common JJ cord-022526-j9kg00qf 5409 2 mechanical mechanical JJ cord-022526-j9kg00qf 5409 3 injuries injury NNS cord-022526-j9kg00qf 5409 4 include include VBP cord-022526-j9kg00qf 5409 5 blunt blunt JJ cord-022526-j9kg00qf 5409 6 or or CC cord-022526-j9kg00qf 5409 7 perforating perforate VBG cord-022526-j9kg00qf 5409 8 trauma trauma NN cord-022526-j9kg00qf 5409 9 to to IN cord-022526-j9kg00qf 5409 10 the the DT cord-022526-j9kg00qf 5409 11 abdominal abdominal JJ cord-022526-j9kg00qf 5409 12 wall wall NN cord-022526-j9kg00qf 5409 13 , , , cord-022526-j9kg00qf 5409 14 breeding breeding NN cord-022526-j9kg00qf 5409 15 and and CC cord-022526-j9kg00qf 5409 16 foaling foal VBG cord-022526-j9kg00qf 5409 17 accidents accident NNS cord-022526-j9kg00qf 5409 18 , , , cord-022526-j9kg00qf 5409 19 and and CC cord-022526-j9kg00qf 5409 20 abdominal abdominal JJ cord-022526-j9kg00qf 5409 21 surgery surgery NN cord-022526-j9kg00qf 5409 22 . . . cord-022526-j9kg00qf 5410 1 A a DT cord-022526-j9kg00qf 5410 2 variety variety NN cord-022526-j9kg00qf 5410 3 of of IN cord-022526-j9kg00qf 5410 4 traumatic traumatic JJ cord-022526-j9kg00qf 5410 5 insults insult NNS cord-022526-j9kg00qf 5410 6 of of IN cord-022526-j9kg00qf 5410 7 iatrogenic iatrogenic JJ cord-022526-j9kg00qf 5410 8 origin origin NN cord-022526-j9kg00qf 5410 9 can can MD cord-022526-j9kg00qf 5410 10 cause cause VB cord-022526-j9kg00qf 5410 11 peritonitis peritonitis NN cord-022526-j9kg00qf 5410 12 , , , cord-022526-j9kg00qf 5410 13 such such JJ cord-022526-j9kg00qf 5410 14 as as IN cord-022526-j9kg00qf 5410 15 the the DT cord-022526-j9kg00qf 5410 16 pathogenesis pathogenesis NN cord-022526-j9kg00qf 5410 17 of of IN cord-022526-j9kg00qf 5410 18 peritonitis peritonitis NN cord-022526-j9kg00qf 5410 19 as as IN cord-022526-j9kg00qf 5410 20 a a DT cord-022526-j9kg00qf 5410 21 series series NN cord-022526-j9kg00qf 5410 22 of of IN cord-022526-j9kg00qf 5410 23 stages stage NNS cord-022526-j9kg00qf 5410 24 , , , cord-022526-j9kg00qf 5410 25 as as IN cord-022526-j9kg00qf 5410 26 reviewed review VBN cord-022526-j9kg00qf 5410 27 and and CC cord-022526-j9kg00qf 5410 28 described describe VBN cord-022526-j9kg00qf 5410 29 by by IN cord-022526-j9kg00qf 5410 30 Trent Trent NNP cord-022526-j9kg00qf 5410 31 , , , cord-022526-j9kg00qf 5410 32 is be VBZ cord-022526-j9kg00qf 5410 33 useful useful JJ cord-022526-j9kg00qf 5410 34 . . . cord-022526-j9kg00qf 5411 1 2 2 LS cord-022526-j9kg00qf 5412 1 The the DT cord-022526-j9kg00qf 5412 2 contamination contamination NN cord-022526-j9kg00qf 5412 3 stage stage NN cord-022526-j9kg00qf 5412 4 , , , cord-022526-j9kg00qf 5412 5 lasting last VBG cord-022526-j9kg00qf 5412 6 3 3 CD cord-022526-j9kg00qf 5412 7 to to TO cord-022526-j9kg00qf 5412 8 6 6 CD cord-022526-j9kg00qf 5412 9 hours hour NNS cord-022526-j9kg00qf 5412 10 , , , cord-022526-j9kg00qf 5412 11 involves involve VBZ cord-022526-j9kg00qf 5412 12 introduction introduction NN cord-022526-j9kg00qf 5412 13 of of IN cord-022526-j9kg00qf 5412 14 bacteria bacteria NNS cord-022526-j9kg00qf 5412 15 into into IN cord-022526-j9kg00qf 5412 16 the the DT cord-022526-j9kg00qf 5412 17 peritoneum peritoneum NN cord-022526-j9kg00qf 5412 18 and and CC cord-022526-j9kg00qf 5412 19 initiation initiation NN cord-022526-j9kg00qf 5412 20 of of IN cord-022526-j9kg00qf 5412 21 the the DT cord-022526-j9kg00qf 5412 22 acute acute JJ cord-022526-j9kg00qf 5412 23 inflammatory inflammatory JJ cord-022526-j9kg00qf 5412 24 response response NN cord-022526-j9kg00qf 5412 25 previously previously RB cord-022526-j9kg00qf 5412 26 described describe VBD cord-022526-j9kg00qf 5412 27 . . . cord-022526-j9kg00qf 5413 1 If if IN cord-022526-j9kg00qf 5413 2 the the DT cord-022526-j9kg00qf 5413 3 organisms organism NNS cord-022526-j9kg00qf 5413 4 are be VBP cord-022526-j9kg00qf 5413 5 not not RB cord-022526-j9kg00qf 5413 6 eliminated eliminate VBN cord-022526-j9kg00qf 5413 7 and and CC cord-022526-j9kg00qf 5413 8 infection infection NN cord-022526-j9kg00qf 5413 9 is be VBZ cord-022526-j9kg00qf 5413 10 established establish VBN cord-022526-j9kg00qf 5413 11 , , , cord-022526-j9kg00qf 5413 12 the the DT cord-022526-j9kg00qf 5413 13 process process NN cord-022526-j9kg00qf 5413 14 evolves evolve VBZ cord-022526-j9kg00qf 5413 15 to to IN cord-022526-j9kg00qf 5413 16 the the DT cord-022526-j9kg00qf 5413 17 stage stage NN cord-022526-j9kg00qf 5413 18 of of IN cord-022526-j9kg00qf 5413 19 acute acute JJ cord-022526-j9kg00qf 5413 20 diffuse diffuse JJ cord-022526-j9kg00qf 5413 21 peritonitis peritonitis NN cord-022526-j9kg00qf 5413 22 . . . cord-022526-j9kg00qf 5414 1 Although although IN cord-022526-j9kg00qf 5414 2 the the DT cord-022526-j9kg00qf 5414 3 overall overall JJ cord-022526-j9kg00qf 5414 4 movement movement NN cord-022526-j9kg00qf 5414 5 of of IN cord-022526-j9kg00qf 5414 6 contaminants contaminant NNS cord-022526-j9kg00qf 5414 7 is be VBZ cord-022526-j9kg00qf 5414 8 toward toward IN cord-022526-j9kg00qf 5414 9 the the DT cord-022526-j9kg00qf 5414 10 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5414 11 stomata stoma NNS cord-022526-j9kg00qf 5414 12 and and CC cord-022526-j9kg00qf 5414 13 into into IN cord-022526-j9kg00qf 5414 14 the the DT cord-022526-j9kg00qf 5414 15 thoracic thoracic JJ cord-022526-j9kg00qf 5414 16 duct duct NN cord-022526-j9kg00qf 5414 17 , , , cord-022526-j9kg00qf 5414 18 the the DT cord-022526-j9kg00qf 5414 19 nature nature NN cord-022526-j9kg00qf 5414 20 of of IN cord-022526-j9kg00qf 5414 21 the the DT cord-022526-j9kg00qf 5414 22 peritoneal peritoneal JJ cord-022526-j9kg00qf 5414 23 circulation circulation NN cord-022526-j9kg00qf 5414 24 is be VBZ cord-022526-j9kg00qf 5414 25 such such JJ cord-022526-j9kg00qf 5414 26 that that IN cord-022526-j9kg00qf 5414 27 regardless regardless RB cord-022526-j9kg00qf 5414 28 of of IN cord-022526-j9kg00qf 5414 29 the the DT cord-022526-j9kg00qf 5414 30 location location NN cord-022526-j9kg00qf 5414 31 of of IN cord-022526-j9kg00qf 5414 32 the the DT cord-022526-j9kg00qf 5414 33 initial initial JJ cord-022526-j9kg00qf 5414 34 contamination contamination NN cord-022526-j9kg00qf 5414 35 , , , cord-022526-j9kg00qf 5414 36 bacteria bacteria NNS cord-022526-j9kg00qf 5414 37 spread spread VBN cord-022526-j9kg00qf 5414 38 throughout throughout IN cord-022526-j9kg00qf 5414 39 the the DT cord-022526-j9kg00qf 5414 40 peritoneum peritoneum NN cord-022526-j9kg00qf 5414 41 within within IN cord-022526-j9kg00qf 5414 42 several several JJ cord-022526-j9kg00qf 5414 43 hours hour NNS cord-022526-j9kg00qf 5414 44 . . . cord-022526-j9kg00qf 5415 1 The the DT cord-022526-j9kg00qf 5415 2 stage stage NN cord-022526-j9kg00qf 5415 3 of of IN cord-022526-j9kg00qf 5415 4 acute acute JJ cord-022526-j9kg00qf 5415 5 diffuse diffuse JJ cord-022526-j9kg00qf 5415 6 peritonitis peritonitis NN cord-022526-j9kg00qf 5415 7 lasts last VBZ cord-022526-j9kg00qf 5415 8 up up IN cord-022526-j9kg00qf 5415 9 to to TO cord-022526-j9kg00qf 5415 10 5 5 CD cord-022526-j9kg00qf 5415 11 days day NNS cord-022526-j9kg00qf 5415 12 . . . cord-022526-j9kg00qf 5416 1 The the DT cord-022526-j9kg00qf 5416 2 inflammatory inflammatory JJ cord-022526-j9kg00qf 5416 3 response response NN cord-022526-j9kg00qf 5416 4 persists persist VBZ cord-022526-j9kg00qf 5416 5 and and CC cord-022526-j9kg00qf 5416 6 escalates escalate VBZ cord-022526-j9kg00qf 5416 7 with with IN cord-022526-j9kg00qf 5416 8 continued continue VBN cord-022526-j9kg00qf 5416 9 exudation exudation NN cord-022526-j9kg00qf 5416 10 of of IN cord-022526-j9kg00qf 5416 11 proteinaceous proteinaceous JJ cord-022526-j9kg00qf 5416 12 fluid fluid NN cord-022526-j9kg00qf 5416 13 and and CC cord-022526-j9kg00qf 5416 14 influx influx NN cord-022526-j9kg00qf 5416 15 of of IN cord-022526-j9kg00qf 5416 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 5416 17 cells cell NNS cord-022526-j9kg00qf 5416 18 . . . cord-022526-j9kg00qf 5417 1 Offending offend VBG cord-022526-j9kg00qf 5417 2 organisms organism NNS cord-022526-j9kg00qf 5417 3 are be VBP cord-022526-j9kg00qf 5417 4 delivered deliver VBN cord-022526-j9kg00qf 5417 5 to to IN cord-022526-j9kg00qf 5417 6 the the DT cord-022526-j9kg00qf 5417 7 lymphatic lymphatic JJ cord-022526-j9kg00qf 5417 8 system system NN cord-022526-j9kg00qf 5417 9 and and CC cord-022526-j9kg00qf 5417 10 may may MD cord-022526-j9kg00qf 5417 11 be be VB cord-022526-j9kg00qf 5417 12 eliminated eliminate VBN cord-022526-j9kg00qf 5417 13 by by IN cord-022526-j9kg00qf 5417 14 the the DT cord-022526-j9kg00qf 5417 15 immune immune JJ cord-022526-j9kg00qf 5417 16 system system NN cord-022526-j9kg00qf 5417 17 . . . cord-022526-j9kg00qf 5418 1 Organisms organism NNS cord-022526-j9kg00qf 5418 2 , , , cord-022526-j9kg00qf 5418 3 however however RB cord-022526-j9kg00qf 5418 4 , , , cord-022526-j9kg00qf 5418 5 may may MD cord-022526-j9kg00qf 5418 6 gain gain VB cord-022526-j9kg00qf 5418 7 access access NN cord-022526-j9kg00qf 5418 8 to to IN cord-022526-j9kg00qf 5418 9 the the DT cord-022526-j9kg00qf 5418 10 systemic systemic JJ cord-022526-j9kg00qf 5418 11 circulation circulation NN cord-022526-j9kg00qf 5418 12 in in IN cord-022526-j9kg00qf 5418 13 sufficient sufficient JJ cord-022526-j9kg00qf 5418 14 numbers number NNS cord-022526-j9kg00qf 5418 15 to to TO cord-022526-j9kg00qf 5418 16 result result VB cord-022526-j9kg00qf 5418 17 in in IN cord-022526-j9kg00qf 5418 18 clinically clinically RB cord-022526-j9kg00qf 5418 19 relevant relevant JJ cord-022526-j9kg00qf 5418 20 septicemia septicemia NN cord-022526-j9kg00qf 5418 21 . . . cord-022526-j9kg00qf 5419 1 In in IN cord-022526-j9kg00qf 5419 2 human human JJ cord-022526-j9kg00qf 5419 3 beings being NNS cord-022526-j9kg00qf 5419 4 and and CC cord-022526-j9kg00qf 5419 5 laboratory laboratory NN cord-022526-j9kg00qf 5419 6 animals animal NNS cord-022526-j9kg00qf 5419 7 having have VBG cord-022526-j9kg00qf 5419 8 undergone undergo VBN cord-022526-j9kg00qf 5419 9 polymicrobial polymicrobial JJ cord-022526-j9kg00qf 5419 10 contamination contamination NN cord-022526-j9kg00qf 5419 11 of of IN cord-022526-j9kg00qf 5419 12 the the DT cord-022526-j9kg00qf 5419 13 peritoneum peritoneum NN cord-022526-j9kg00qf 5419 14 , , , cord-022526-j9kg00qf 5419 15 the the DT cord-022526-j9kg00qf 5419 16 organisms organism NNS cord-022526-j9kg00qf 5419 17 causing cause VBG cord-022526-j9kg00qf 5419 18 septicemia septicemia NN cord-022526-j9kg00qf 5419 19 at at IN cord-022526-j9kg00qf 5419 20 this this DT cord-022526-j9kg00qf 5419 21 stage stage NN cord-022526-j9kg00qf 5419 22 are be VBP cord-022526-j9kg00qf 5419 23 usually usually RB cord-022526-j9kg00qf 5419 24 coliforms coliform NNS cord-022526-j9kg00qf 5419 25 , , , cord-022526-j9kg00qf 5419 26 E. E. NNP cord-022526-j9kg00qf 5419 27 coli coli NNS cord-022526-j9kg00qf 5419 28 in in IN cord-022526-j9kg00qf 5419 29 particular particular JJ cord-022526-j9kg00qf 5419 30 . . . cord-022526-j9kg00qf 5420 1 This this DT cord-022526-j9kg00qf 5420 2 stage stage NN cord-022526-j9kg00qf 5420 3 of of IN cord-022526-j9kg00qf 5420 4 the the DT cord-022526-j9kg00qf 5420 5 disease disease NN cord-022526-j9kg00qf 5420 6 process process NN cord-022526-j9kg00qf 5420 7 has have VBZ cord-022526-j9kg00qf 5420 8 the the DT cord-022526-j9kg00qf 5420 9 highest high JJS cord-022526-j9kg00qf 5420 10 mortality mortality NN cord-022526-j9kg00qf 5420 11 because because IN cord-022526-j9kg00qf 5420 12 of of IN cord-022526-j9kg00qf 5420 13 the the DT cord-022526-j9kg00qf 5420 14 effects effect NNS cord-022526-j9kg00qf 5420 15 of of IN cord-022526-j9kg00qf 5420 16 severe severe JJ cord-022526-j9kg00qf 5420 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5420 18 inflammation inflammation NN cord-022526-j9kg00qf 5420 19 , , , cord-022526-j9kg00qf 5420 20 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5420 21 , , , cord-022526-j9kg00qf 5420 22 and and CC cord-022526-j9kg00qf 5420 23 septicemia septicemia NN cord-022526-j9kg00qf 5420 24 . . . cord-022526-j9kg00qf 5421 1 If if IN cord-022526-j9kg00qf 5421 2 the the DT cord-022526-j9kg00qf 5421 3 animal animal NN cord-022526-j9kg00qf 5421 4 survives survive VBZ cord-022526-j9kg00qf 5421 5 this this DT cord-022526-j9kg00qf 5421 6 stage stage NN cord-022526-j9kg00qf 5421 7 but but CC cord-022526-j9kg00qf 5421 8 fails fail VBZ cord-022526-j9kg00qf 5421 9 to to TO cord-022526-j9kg00qf 5421 10 eliminate eliminate VB cord-022526-j9kg00qf 5421 11 the the DT cord-022526-j9kg00qf 5421 12 infection infection NN cord-022526-j9kg00qf 5421 13 in in IN cord-022526-j9kg00qf 5421 14 the the DT cord-022526-j9kg00qf 5421 15 peritoneal peritoneal JJ cord-022526-j9kg00qf 5421 16 cavity cavity NN cord-022526-j9kg00qf 5421 17 , , , cord-022526-j9kg00qf 5421 18 the the DT cord-022526-j9kg00qf 5421 19 disease disease NN cord-022526-j9kg00qf 5421 20 enters enter VBZ cord-022526-j9kg00qf 5421 21 a a DT cord-022526-j9kg00qf 5421 22 transitional transitional JJ cord-022526-j9kg00qf 5421 23 phase phase NN cord-022526-j9kg00qf 5421 24 referred refer VBN cord-022526-j9kg00qf 5421 25 to to IN cord-022526-j9kg00qf 5421 26 as as IN cord-022526-j9kg00qf 5421 27 the the DT cord-022526-j9kg00qf 5421 28 acute acute JJ cord-022526-j9kg00qf 5421 29 adhesive adhesive NN cord-022526-j9kg00qf 5421 30 ( ( -LRB- cord-022526-j9kg00qf 5421 31 or or CC cord-022526-j9kg00qf 5421 32 localizing localize VBG cord-022526-j9kg00qf 5421 33 ) ) -RRB- cord-022526-j9kg00qf 5421 34 stage stage NN cord-022526-j9kg00qf 5421 35 . . . cord-022526-j9kg00qf 5422 1 This this DT cord-022526-j9kg00qf 5422 2 stage stage NN cord-022526-j9kg00qf 5422 3 occupies occupy VBZ cord-022526-j9kg00qf 5422 4 a a DT cord-022526-j9kg00qf 5422 5 time time NN cord-022526-j9kg00qf 5422 6 frame frame NN cord-022526-j9kg00qf 5422 7 of of IN cord-022526-j9kg00qf 5422 8 perhaps perhaps RB cord-022526-j9kg00qf 5422 9 4 4 CD cord-022526-j9kg00qf 5422 10 to to TO cord-022526-j9kg00qf 5422 11 10 10 CD cord-022526-j9kg00qf 5422 12 days day NNS cord-022526-j9kg00qf 5422 13 after after IN cord-022526-j9kg00qf 5422 14 the the DT cord-022526-j9kg00qf 5422 15 initial initial JJ cord-022526-j9kg00qf 5422 16 insult insult NN cord-022526-j9kg00qf 5422 17 . . . cord-022526-j9kg00qf 5423 1 Neutrophils neutrophil NNS cord-022526-j9kg00qf 5423 2 are be VBP cord-022526-j9kg00qf 5423 3 still still RB cord-022526-j9kg00qf 5423 4 active active JJ cord-022526-j9kg00qf 5423 5 , , , cord-022526-j9kg00qf 5423 6 macrophages macrophage NNS cord-022526-j9kg00qf 5423 7 are be VBP cord-022526-j9kg00qf 5423 8 increasing increase VBG cord-022526-j9kg00qf 5423 9 in in IN cord-022526-j9kg00qf 5423 10 numbers number NNS cord-022526-j9kg00qf 5423 11 , , , cord-022526-j9kg00qf 5423 12 and and CC cord-022526-j9kg00qf 5423 13 fibrin fibrin NN cord-022526-j9kg00qf 5423 14 aggregates aggregate NNS cord-022526-j9kg00qf 5423 15 are be VBP cord-022526-j9kg00qf 5423 16 being be VBG cord-022526-j9kg00qf 5423 17 organized organize VBN cord-022526-j9kg00qf 5423 18 or or CC cord-022526-j9kg00qf 5423 19 lysed lyse VBN cord-022526-j9kg00qf 5423 20 . . . cord-022526-j9kg00qf 5424 1 In in IN cord-022526-j9kg00qf 5424 2 human human JJ cord-022526-j9kg00qf 5424 3 beings being NNS cord-022526-j9kg00qf 5424 4 and and CC cord-022526-j9kg00qf 5424 5 laboratory laboratory NN cord-022526-j9kg00qf 5424 6 animals animal NNS cord-022526-j9kg00qf 5424 7 , , , cord-022526-j9kg00qf 5424 8 selective selective JJ cord-022526-j9kg00qf 5424 9 reduction reduction NN cord-022526-j9kg00qf 5424 10 and and CC cord-022526-j9kg00qf 5424 11 synergism synergism NN cord-022526-j9kg00qf 5424 12 continue continue VBP cord-022526-j9kg00qf 5424 13 such such JJ cord-022526-j9kg00qf 5424 14 that that IN cord-022526-j9kg00qf 5424 15 anaerobes anaerobe NNS cord-022526-j9kg00qf 5424 16 and and CC cord-022526-j9kg00qf 5424 17 gram gram NN cord-022526-j9kg00qf 5424 18 - - HYPH cord-022526-j9kg00qf 5424 19 negative negative JJ cord-022526-j9kg00qf 5424 20 aerobes aerobe NNS cord-022526-j9kg00qf 5424 21 predominate predominate VBP cord-022526-j9kg00qf 5424 22 . . . cord-022526-j9kg00qf 5425 1 If if IN cord-022526-j9kg00qf 5425 2 infection infection NN cord-022526-j9kg00qf 5425 3 persists persist VBZ cord-022526-j9kg00qf 5425 4 beyond beyond IN cord-022526-j9kg00qf 5425 5 this this DT cord-022526-j9kg00qf 5425 6 point point NN cord-022526-j9kg00qf 5425 7 , , , cord-022526-j9kg00qf 5425 8 organization organization NN cord-022526-j9kg00qf 5425 9 of of IN cord-022526-j9kg00qf 5425 10 fibrin fibrin NN cord-022526-j9kg00qf 5425 11 proceeds proceed NNS cord-022526-j9kg00qf 5425 12 and and CC cord-022526-j9kg00qf 5425 13 organisms organism NNS cord-022526-j9kg00qf 5425 14 become become VBP cord-022526-j9kg00qf 5425 15 isolated isolate VBN cord-022526-j9kg00qf 5425 16 from from IN cord-022526-j9kg00qf 5425 17 host host NN cord-022526-j9kg00qf 5425 18 defenses defense NNS cord-022526-j9kg00qf 5425 19 . . . cord-022526-j9kg00qf 5426 1 At at IN cord-022526-j9kg00qf 5426 2 this this DT cord-022526-j9kg00qf 5426 3 point point NN cord-022526-j9kg00qf 5426 4 , , , cord-022526-j9kg00qf 5426 5 the the DT cord-022526-j9kg00qf 5426 6 disease disease NN cord-022526-j9kg00qf 5426 7 process process NN cord-022526-j9kg00qf 5426 8 enters enter VBZ cord-022526-j9kg00qf 5426 9 the the DT cord-022526-j9kg00qf 5426 10 stage stage NN cord-022526-j9kg00qf 5426 11 of of IN cord-022526-j9kg00qf 5426 12 chronic chronic JJ cord-022526-j9kg00qf 5426 13 abscessation abscessation NN cord-022526-j9kg00qf 5426 14 . . . cord-022526-j9kg00qf 5427 1 This this DT cord-022526-j9kg00qf 5427 2 stage stage NN cord-022526-j9kg00qf 5427 3 can can MD cord-022526-j9kg00qf 5427 4 begin begin VB cord-022526-j9kg00qf 5427 5 as as RB cord-022526-j9kg00qf 5427 6 early early RB cord-022526-j9kg00qf 5427 7 as as IN cord-022526-j9kg00qf 5427 8 8 8 CD cord-022526-j9kg00qf 5427 9 days day NNS cord-022526-j9kg00qf 5427 10 after after IN cord-022526-j9kg00qf 5427 11 inoculation inoculation NN cord-022526-j9kg00qf 5427 12 and and CC cord-022526-j9kg00qf 5427 13 persists persist VBZ cord-022526-j9kg00qf 5427 14 indefinitely indefinitely RB cord-022526-j9kg00qf 5427 15 . . . cord-022526-j9kg00qf 5428 1 Clinical clinical JJ cord-022526-j9kg00qf 5428 2 signs sign NNS cord-022526-j9kg00qf 5428 3 of of IN cord-022526-j9kg00qf 5428 4 peritonitis peritonitis NN cord-022526-j9kg00qf 5428 5 depend depend VB cord-022526-j9kg00qf 5428 6 on on IN cord-022526-j9kg00qf 5428 7 the the DT cord-022526-j9kg00qf 5428 8 primary primary JJ cord-022526-j9kg00qf 5428 9 disease disease NN cord-022526-j9kg00qf 5428 10 process process NN cord-022526-j9kg00qf 5428 11 , , , cord-022526-j9kg00qf 5428 12 the the DT cord-022526-j9kg00qf 5428 13 duration duration NN cord-022526-j9kg00qf 5428 14 of of IN cord-022526-j9kg00qf 5428 15 the the DT cord-022526-j9kg00qf 5428 16 problem problem NN cord-022526-j9kg00qf 5428 17 , , , cord-022526-j9kg00qf 5428 18 and and CC cord-022526-j9kg00qf 5428 19 the the DT cord-022526-j9kg00qf 5428 20 extent extent NN cord-022526-j9kg00qf 5428 21 of of IN cord-022526-j9kg00qf 5428 22 peritoneal peritoneal JJ cord-022526-j9kg00qf 5428 23 inflammation inflammation NN cord-022526-j9kg00qf 5428 24 . . . cord-022526-j9kg00qf 5429 1 Localized localized JJ cord-022526-j9kg00qf 5429 2 peritonitis peritonitis NN cord-022526-j9kg00qf 5429 3 may may MD cord-022526-j9kg00qf 5429 4 have have VB cord-022526-j9kg00qf 5429 5 few few JJ cord-022526-j9kg00qf 5429 6 or or CC cord-022526-j9kg00qf 5429 7 no no DT cord-022526-j9kg00qf 5429 8 systemic systemic JJ cord-022526-j9kg00qf 5429 9 manifestations manifestation NNS cord-022526-j9kg00qf 5429 10 , , , cord-022526-j9kg00qf 5429 11 whereas whereas IN cord-022526-j9kg00qf 5429 12 severe severe JJ cord-022526-j9kg00qf 5429 13 localized localize VBN cord-022526-j9kg00qf 5429 14 or or CC cord-022526-j9kg00qf 5429 15 generalized generalized JJ cord-022526-j9kg00qf 5429 16 peritonitis peritonitis NN cord-022526-j9kg00qf 5429 17 often often RB cord-022526-j9kg00qf 5429 18 is be VBZ cord-022526-j9kg00qf 5429 19 accompanied accompany VBN cord-022526-j9kg00qf 5429 20 by by IN cord-022526-j9kg00qf 5429 21 severe severe JJ cord-022526-j9kg00qf 5429 22 toxemia toxemia NN cord-022526-j9kg00qf 5429 23 or or CC cord-022526-j9kg00qf 5429 24 septicemia septicemia NN cord-022526-j9kg00qf 5429 25 or or CC cord-022526-j9kg00qf 5429 26 both both DT cord-022526-j9kg00qf 5429 27 . . . cord-022526-j9kg00qf 5430 1 Septic septic JJ cord-022526-j9kg00qf 5430 2 peritonitis peritonitis NN cord-022526-j9kg00qf 5430 3 usually usually RB cord-022526-j9kg00qf 5430 4 causes cause VBZ cord-022526-j9kg00qf 5430 5 more more RBR cord-022526-j9kg00qf 5430 6 severe severe JJ cord-022526-j9kg00qf 5430 7 clinical clinical JJ cord-022526-j9kg00qf 5430 8 signs sign NNS cord-022526-j9kg00qf 5430 9 because because IN cord-022526-j9kg00qf 5430 10 of of IN cord-022526-j9kg00qf 5430 11 the the DT cord-022526-j9kg00qf 5430 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 5430 13 mediators mediator NNS cord-022526-j9kg00qf 5430 14 released release VBN cord-022526-j9kg00qf 5430 15 in in IN cord-022526-j9kg00qf 5430 16 response response NN cord-022526-j9kg00qf 5430 17 to to IN cord-022526-j9kg00qf 5430 18 bacterial bacterial JJ cord-022526-j9kg00qf 5430 19 toxins toxin NNS cord-022526-j9kg00qf 5430 20 and and CC cord-022526-j9kg00qf 5430 21 because because IN cord-022526-j9kg00qf 5430 22 of of IN cord-022526-j9kg00qf 5430 23 the the DT cord-022526-j9kg00qf 5430 24 presence presence NN cord-022526-j9kg00qf 5430 25 of of IN cord-022526-j9kg00qf 5430 26 endotoxin endotoxin NN cord-022526-j9kg00qf 5430 27 when when WRB cord-022526-j9kg00qf 5430 28 gram gram NN cord-022526-j9kg00qf 5430 29 - - HYPH cord-022526-j9kg00qf 5430 30 negative negative JJ cord-022526-j9kg00qf 5430 31 organisms organism NNS cord-022526-j9kg00qf 5430 32 are be VBP cord-022526-j9kg00qf 5430 33 involved involve VBN cord-022526-j9kg00qf 5430 34 . . . cord-022526-j9kg00qf 5431 1 Most Most JJS cord-022526-j9kg00qf 5431 2 clinical clinical JJ cord-022526-j9kg00qf 5431 3 signs sign NNS cord-022526-j9kg00qf 5431 4 are be VBP cord-022526-j9kg00qf 5431 5 nonspecific nonspecific JJ cord-022526-j9kg00qf 5431 6 and and CC cord-022526-j9kg00qf 5431 7 include include VBP cord-022526-j9kg00qf 5431 8 fever fever NN cord-022526-j9kg00qf 5431 9 , , , cord-022526-j9kg00qf 5431 10 depression depression NN cord-022526-j9kg00qf 5431 11 , , , cord-022526-j9kg00qf 5431 12 inappetance inappetance NN cord-022526-j9kg00qf 5431 13 , , , cord-022526-j9kg00qf 5431 14 decreased decrease VBD cord-022526-j9kg00qf 5431 15 borborygmi borborygmi NN cord-022526-j9kg00qf 5431 16 , , , cord-022526-j9kg00qf 5431 17 and and CC cord-022526-j9kg00qf 5431 18 dehydration dehydration NN cord-022526-j9kg00qf 5431 19 . . . cord-022526-j9kg00qf 5432 1 Additional additional JJ cord-022526-j9kg00qf 5432 2 signs sign NNS cord-022526-j9kg00qf 5432 3 , , , cord-022526-j9kg00qf 5432 4 reported report VBN cord-022526-j9kg00qf 5432 5 in in IN cord-022526-j9kg00qf 5432 6 30 30 CD cord-022526-j9kg00qf 5432 7 horses horse NNS cord-022526-j9kg00qf 5432 8 ( ( -LRB- cord-022526-j9kg00qf 5432 9 ages age NNS cord-022526-j9kg00qf 5432 10 2 2 CD cord-022526-j9kg00qf 5432 11 months month NNS cord-022526-j9kg00qf 5432 12 to to IN cord-022526-j9kg00qf 5432 13 16 16 CD cord-022526-j9kg00qf 5432 14 years year NNS cord-022526-j9kg00qf 5432 15 ) ) -RRB- cord-022526-j9kg00qf 5432 16 with with IN cord-022526-j9kg00qf 5432 17 peritonitis peritonitis NN cord-022526-j9kg00qf 5432 18 , , , cord-022526-j9kg00qf 5432 19 were be VBD cord-022526-j9kg00qf 5432 20 colic colic NN cord-022526-j9kg00qf 5432 21 , , , cord-022526-j9kg00qf 5432 22 ileus ileus NN cord-022526-j9kg00qf 5432 23 , , , cord-022526-j9kg00qf 5432 24 weight weight NN cord-022526-j9kg00qf 5432 25 loss loss NN cord-022526-j9kg00qf 5432 26 , , , cord-022526-j9kg00qf 5432 27 and and CC cord-022526-j9kg00qf 5432 28 diarrhea diarrhea NN cord-022526-j9kg00qf 5432 29 . . . cord-022526-j9kg00qf 5433 1 14 14 CD cord-022526-j9kg00qf 5433 2 Horses horse NNS cord-022526-j9kg00qf 5433 3 with with IN cord-022526-j9kg00qf 5433 4 peracute peracute NN cord-022526-j9kg00qf 5433 5 peritonitis peritonitis NN cord-022526-j9kg00qf 5433 6 , , , cord-022526-j9kg00qf 5433 7 as as IN cord-022526-j9kg00qf 5433 8 occurs occur VBZ cord-022526-j9kg00qf 5433 9 with with IN cord-022526-j9kg00qf 5433 10 rupture rupture NN cord-022526-j9kg00qf 5433 11 of of IN cord-022526-j9kg00qf 5433 12 the the DT cord-022526-j9kg00qf 5433 13 bowel bowel NN cord-022526-j9kg00qf 5433 14 or or CC cord-022526-j9kg00qf 5433 15 rectal rectal JJ cord-022526-j9kg00qf 5433 16 tear tear NN cord-022526-j9kg00qf 5433 17 , , , cord-022526-j9kg00qf 5433 18 have have VBP cord-022526-j9kg00qf 5433 19 severe severe JJ cord-022526-j9kg00qf 5433 20 toxemia toxemia NN cord-022526-j9kg00qf 5433 21 , , , cord-022526-j9kg00qf 5433 22 weakness weakness NN cord-022526-j9kg00qf 5433 23 , , , cord-022526-j9kg00qf 5433 24 depression depression NN cord-022526-j9kg00qf 5433 25 or or CC cord-022526-j9kg00qf 5433 26 severe severe JJ cord-022526-j9kg00qf 5433 27 colic colic NN cord-022526-j9kg00qf 5433 28 , , , cord-022526-j9kg00qf 5433 29 tachycardia tachycardia NN cord-022526-j9kg00qf 5433 30 , , , cord-022526-j9kg00qf 5433 31 tachypnea tachypnea NNP cord-022526-j9kg00qf 5433 32 , , , cord-022526-j9kg00qf 5433 33 and and CC cord-022526-j9kg00qf 5433 34 circulatory circulatory JJ cord-022526-j9kg00qf 5433 35 failure failure NN cord-022526-j9kg00qf 5433 36 . . . cord-022526-j9kg00qf 5434 1 Fever fever NN cord-022526-j9kg00qf 5434 2 may may MD cord-022526-j9kg00qf 5434 3 not not RB cord-022526-j9kg00qf 5434 4 be be VB cord-022526-j9kg00qf 5434 5 present present JJ cord-022526-j9kg00qf 5434 6 depending depend VBG cord-022526-j9kg00qf 5434 7 on on IN cord-022526-j9kg00qf 5434 8 the the DT cord-022526-j9kg00qf 5434 9 degree degree NN cord-022526-j9kg00qf 5434 10 of of IN cord-022526-j9kg00qf 5434 11 shock shock NN cord-022526-j9kg00qf 5434 12 . . . cord-022526-j9kg00qf 5435 1 Typical typical JJ cord-022526-j9kg00qf 5435 2 clinical clinical JJ cord-022526-j9kg00qf 5435 3 findings finding NNS cord-022526-j9kg00qf 5435 4 include include VBP cord-022526-j9kg00qf 5435 5 sweating sweating NN cord-022526-j9kg00qf 5435 6 , , , cord-022526-j9kg00qf 5435 7 pawing paw VBG cord-022526-j9kg00qf 5435 8 , , , cord-022526-j9kg00qf 5435 9 muscle muscle NN cord-022526-j9kg00qf 5435 10 fasciculations fasciculation NNS cord-022526-j9kg00qf 5435 11 , , , cord-022526-j9kg00qf 5435 12 weak weak JJ cord-022526-j9kg00qf 5435 13 peripheral peripheral JJ cord-022526-j9kg00qf 5435 14 pulses pulse NNS cord-022526-j9kg00qf 5435 15 , , , cord-022526-j9kg00qf 5435 16 red red JJ cord-022526-j9kg00qf 5435 17 to to IN cord-022526-j9kg00qf 5435 18 purple purple JJ cord-022526-j9kg00qf 5435 19 mucous mucous JJ cord-022526-j9kg00qf 5435 20 membranes membrane NNS cord-022526-j9kg00qf 5435 21 , , , cord-022526-j9kg00qf 5435 22 prolonged prolong VBN cord-022526-j9kg00qf 5435 23 capillary capillary JJ cord-022526-j9kg00qf 5435 24 refill refill NN cord-022526-j9kg00qf 5435 25 time time NN cord-022526-j9kg00qf 5435 26 , , , cord-022526-j9kg00qf 5435 27 and and CC cord-022526-j9kg00qf 5435 28 decreased decrease VBD cord-022526-j9kg00qf 5435 29 skin skin NN cord-022526-j9kg00qf 5435 30 elasticity elasticity NN cord-022526-j9kg00qf 5435 31 . . . cord-022526-j9kg00qf 5436 1 Parietal parietal JJ cord-022526-j9kg00qf 5436 2 pain pain NN cord-022526-j9kg00qf 5436 3 , , , cord-022526-j9kg00qf 5436 4 characterized characterize VBN cord-022526-j9kg00qf 5436 5 by by IN cord-022526-j9kg00qf 5436 6 reluctance reluctance NN cord-022526-j9kg00qf 5436 7 to to TO cord-022526-j9kg00qf 5436 8 move move VB cord-022526-j9kg00qf 5436 9 , , , cord-022526-j9kg00qf 5436 10 splinting splinting NN cord-022526-j9kg00qf 5436 11 of of IN cord-022526-j9kg00qf 5436 12 the the DT cord-022526-j9kg00qf 5436 13 abdominal abdominal JJ cord-022526-j9kg00qf 5436 14 wall wall NN cord-022526-j9kg00qf 5436 15 , , , cord-022526-j9kg00qf 5436 16 and and CC cord-022526-j9kg00qf 5436 17 sensitivity sensitivity NN cord-022526-j9kg00qf 5436 18 to to IN cord-022526-j9kg00qf 5436 19 external external JJ cord-022526-j9kg00qf 5436 20 abdominal abdominal JJ cord-022526-j9kg00qf 5436 21 pressure pressure NN cord-022526-j9kg00qf 5436 22 occur occur VBP cord-022526-j9kg00qf 5436 23 in in IN cord-022526-j9kg00qf 5436 24 some some DT cord-022526-j9kg00qf 5436 25 acute acute JJ cord-022526-j9kg00qf 5436 26 cases case NNS cord-022526-j9kg00qf 5436 27 . . . cord-022526-j9kg00qf 5437 1 Urination urination NN cord-022526-j9kg00qf 5437 2 or or CC cord-022526-j9kg00qf 5437 3 defecation defecation NN cord-022526-j9kg00qf 5437 4 may may MD cord-022526-j9kg00qf 5437 5 be be VB cord-022526-j9kg00qf 5437 6 painful painful JJ cord-022526-j9kg00qf 5437 7 for for IN cord-022526-j9kg00qf 5437 8 the the DT cord-022526-j9kg00qf 5437 9 horse horse NN cord-022526-j9kg00qf 5437 10 , , , cord-022526-j9kg00qf 5437 11 and and CC cord-022526-j9kg00qf 5437 12 urine urine NN cord-022526-j9kg00qf 5437 13 and and CC cord-022526-j9kg00qf 5437 14 fecal fecal JJ cord-022526-j9kg00qf 5437 15 retention retention NN cord-022526-j9kg00qf 5437 16 may may MD cord-022526-j9kg00qf 5437 17 be be VB cord-022526-j9kg00qf 5437 18 evident evident JJ cord-022526-j9kg00qf 5437 19 on on IN cord-022526-j9kg00qf 5437 20 rectal rectal JJ cord-022526-j9kg00qf 5437 21 examination examination NN cord-022526-j9kg00qf 5437 22 . . . cord-022526-j9kg00qf 5438 1 Palpation palpation NN cord-022526-j9kg00qf 5438 2 of of IN cord-022526-j9kg00qf 5438 3 the the DT cord-022526-j9kg00qf 5438 4 abdomen abdomen NN cord-022526-j9kg00qf 5438 5 externally externally RB cord-022526-j9kg00qf 5438 6 may may MD cord-022526-j9kg00qf 5438 7 elicit elicit VB cord-022526-j9kg00qf 5438 8 flinching flinch VBG cord-022526-j9kg00qf 5438 9 , , , cord-022526-j9kg00qf 5438 10 aversion aversion NN cord-022526-j9kg00qf 5438 11 movements movement NNS cord-022526-j9kg00qf 5438 12 , , , cord-022526-j9kg00qf 5438 13 or or CC cord-022526-j9kg00qf 5438 14 groaning groaning NN cord-022526-j9kg00qf 5438 15 . . . cord-022526-j9kg00qf 5439 1 With with IN cord-022526-j9kg00qf 5439 2 extensive extensive JJ cord-022526-j9kg00qf 5439 3 abdominal abdominal JJ cord-022526-j9kg00qf 5439 4 fecal fecal JJ cord-022526-j9kg00qf 5439 5 contamination contamination NN cord-022526-j9kg00qf 5439 6 , , , cord-022526-j9kg00qf 5439 7 rectal rectal JJ cord-022526-j9kg00qf 5439 8 examination examination NN cord-022526-j9kg00qf 5439 9 may may MD cord-022526-j9kg00qf 5439 10 reveal reveal VB cord-022526-j9kg00qf 5439 11 a a DT cord-022526-j9kg00qf 5439 12 gritty gritty JJ cord-022526-j9kg00qf 5439 13 feeling feeling NN cord-022526-j9kg00qf 5439 14 of of IN cord-022526-j9kg00qf 5439 15 the the DT cord-022526-j9kg00qf 5439 16 serosal serosal NN cord-022526-j9kg00qf 5439 17 and and CC cord-022526-j9kg00qf 5439 18 parietal parietal JJ cord-022526-j9kg00qf 5439 19 surface surface NN cord-022526-j9kg00qf 5439 20 of of IN cord-022526-j9kg00qf 5439 21 the the DT cord-022526-j9kg00qf 5439 22 peritoneum peritoneum NN cord-022526-j9kg00qf 5439 23 because because IN cord-022526-j9kg00qf 5439 24 of of IN cord-022526-j9kg00qf 5439 25 fibrin fibrin NN cord-022526-j9kg00qf 5439 26 deposition deposition NN cord-022526-j9kg00qf 5439 27 and and CC cord-022526-j9kg00qf 5439 28 a a DT cord-022526-j9kg00qf 5439 29 dry dry JJ cord-022526-j9kg00qf 5439 30 texture texture NN cord-022526-j9kg00qf 5439 31 of of IN cord-022526-j9kg00qf 5439 32 the the DT cord-022526-j9kg00qf 5439 33 peritoneum peritoneum NN cord-022526-j9kg00qf 5439 34 . . . cord-022526-j9kg00qf 5440 1 In in IN cord-022526-j9kg00qf 5440 2 horses horse NNS cord-022526-j9kg00qf 5440 3 with with IN cord-022526-j9kg00qf 5440 4 more more JJR cord-022526-j9kg00qf 5440 5 chronic chronic JJ cord-022526-j9kg00qf 5440 6 peritonitis peritonitis NN cord-022526-j9kg00qf 5440 7 , , , cord-022526-j9kg00qf 5440 8 rectal rectal JJ cord-022526-j9kg00qf 5440 9 examination examination NN cord-022526-j9kg00qf 5440 10 findings finding NNS cord-022526-j9kg00qf 5440 11 can can MD cord-022526-j9kg00qf 5440 12 include include VB cord-022526-j9kg00qf 5440 13 pain pain NN cord-022526-j9kg00qf 5440 14 on on IN cord-022526-j9kg00qf 5440 15 palpation palpation NN cord-022526-j9kg00qf 5440 16 of of IN cord-022526-j9kg00qf 5440 17 fibrinous fibrinous JJ cord-022526-j9kg00qf 5440 18 or or CC cord-022526-j9kg00qf 5440 19 fibrous fibrous JJ cord-022526-j9kg00qf 5440 20 adhesions adhesion NNS cord-022526-j9kg00qf 5440 21 , , , cord-022526-j9kg00qf 5440 22 intestinal intestinal JJ cord-022526-j9kg00qf 5440 23 impaction impaction NN cord-022526-j9kg00qf 5440 24 or or CC cord-022526-j9kg00qf 5440 25 distention distention NN cord-022526-j9kg00qf 5440 26 following follow VBG cord-022526-j9kg00qf 5440 27 ileus ileus NN cord-022526-j9kg00qf 5440 28 and and CC cord-022526-j9kg00qf 5440 29 dehydration dehydration NN cord-022526-j9kg00qf 5440 30 , , , cord-022526-j9kg00qf 5440 31 an an DT cord-022526-j9kg00qf 5440 32 abdominal abdominal JJ cord-022526-j9kg00qf 5440 33 mass mass NN cord-022526-j9kg00qf 5440 34 ( ( -LRB- cord-022526-j9kg00qf 5440 35 abscess abscess NN cord-022526-j9kg00qf 5440 36 or or CC cord-022526-j9kg00qf 5440 37 neoplasia neoplasia NN cord-022526-j9kg00qf 5440 38 ) ) -RRB- cord-022526-j9kg00qf 5440 39 , , , cord-022526-j9kg00qf 5440 40 or or CC cord-022526-j9kg00qf 5440 41 an an DT cord-022526-j9kg00qf 5440 42 impression impression NN cord-022526-j9kg00qf 5440 43 of of IN cord-022526-j9kg00qf 5440 44 bowel bowel NN cord-022526-j9kg00qf 5440 45 floating float VBG cord-022526-j9kg00qf 5440 46 in in IN cord-022526-j9kg00qf 5440 47 fluid fluid NN cord-022526-j9kg00qf 5440 48 . . . cord-022526-j9kg00qf 5441 1 In in IN cord-022526-j9kg00qf 5441 2 many many JJ cord-022526-j9kg00qf 5441 3 cases case NNS cord-022526-j9kg00qf 5441 4 , , , cord-022526-j9kg00qf 5441 5 one one PRP cord-022526-j9kg00qf 5441 6 can can MD cord-022526-j9kg00qf 5441 7 detect detect VB cord-022526-j9kg00qf 5441 8 no no DT cord-022526-j9kg00qf 5441 9 abnormalities abnormality NNS cord-022526-j9kg00qf 5441 10 on on IN cord-022526-j9kg00qf 5441 11 rectal rectal JJ cord-022526-j9kg00qf 5441 12 examination examination NN cord-022526-j9kg00qf 5441 13 . . . cord-022526-j9kg00qf 5442 1 Horses horse NNS cord-022526-j9kg00qf 5442 2 with with IN cord-022526-j9kg00qf 5442 3 localized localized JJ cord-022526-j9kg00qf 5442 4 , , , cord-022526-j9kg00qf 5442 5 subacute subacute JJ cord-022526-j9kg00qf 5442 6 , , , cord-022526-j9kg00qf 5442 7 or or CC cord-022526-j9kg00qf 5442 8 chronic chronic JJ cord-022526-j9kg00qf 5442 9 peritonitis peritonitis NN cord-022526-j9kg00qf 5442 10 may may MD cord-022526-j9kg00qf 5442 11 have have VB cord-022526-j9kg00qf 5442 12 signs sign NNS cord-022526-j9kg00qf 5442 13 of of IN cord-022526-j9kg00qf 5442 14 chronic chronic JJ cord-022526-j9kg00qf 5442 15 or or CC cord-022526-j9kg00qf 5442 16 intermittent intermittent JJ cord-022526-j9kg00qf 5442 17 colic colic NN cord-022526-j9kg00qf 5442 18 , , , cord-022526-j9kg00qf 5442 19 depression depression NN cord-022526-j9kg00qf 5442 20 , , , cord-022526-j9kg00qf 5442 21 anorexia anorexia NN cord-022526-j9kg00qf 5442 22 , , , cord-022526-j9kg00qf 5442 23 weight weight NN cord-022526-j9kg00qf 5442 24 loss loss NN cord-022526-j9kg00qf 5442 25 , , , cord-022526-j9kg00qf 5442 26 intermittent intermittent JJ cord-022526-j9kg00qf 5442 27 fever fever NN cord-022526-j9kg00qf 5442 28 , , , cord-022526-j9kg00qf 5442 29 ventral ventral JJ cord-022526-j9kg00qf 5442 30 edema edema NN cord-022526-j9kg00qf 5442 31 , , , cord-022526-j9kg00qf 5442 32 exercise exercise NN cord-022526-j9kg00qf 5442 33 intolerance intolerance NN cord-022526-j9kg00qf 5442 34 , , , cord-022526-j9kg00qf 5442 35 decreased decrease VBD cord-022526-j9kg00qf 5442 36 or or CC cord-022526-j9kg00qf 5442 37 absent absent JJ cord-022526-j9kg00qf 5442 38 intestinal intestinal JJ cord-022526-j9kg00qf 5442 39 sounds sound NNS cord-022526-j9kg00qf 5442 40 , , , cord-022526-j9kg00qf 5442 41 and and CC cord-022526-j9kg00qf 5442 42 mild mild JJ cord-022526-j9kg00qf 5442 43 dehydration dehydration NN cord-022526-j9kg00qf 5442 44 . . . cord-022526-j9kg00qf 5443 1 Heart heart NN cord-022526-j9kg00qf 5443 2 rate rate NN cord-022526-j9kg00qf 5443 3 and and CC cord-022526-j9kg00qf 5443 4 respiratory respiratory JJ cord-022526-j9kg00qf 5443 5 rate rate NN cord-022526-j9kg00qf 5443 6 may may MD cord-022526-j9kg00qf 5443 7 be be VB cord-022526-j9kg00qf 5443 8 normal normal JJ cord-022526-j9kg00qf 5443 9 . . . cord-022526-j9kg00qf 5444 1 Fecal fecal JJ cord-022526-j9kg00qf 5444 2 output output NN cord-022526-j9kg00qf 5444 3 may may MD cord-022526-j9kg00qf 5444 4 be be VB cord-022526-j9kg00qf 5444 5 normal normal JJ cord-022526-j9kg00qf 5444 6 ; ; : cord-022526-j9kg00qf 5444 7 however however RB cord-022526-j9kg00qf 5444 8 , , , cord-022526-j9kg00qf 5444 9 horses horse NNS cord-022526-j9kg00qf 5444 10 with with IN cord-022526-j9kg00qf 5444 11 chronic chronic JJ cord-022526-j9kg00qf 5444 12 diarrhea diarrhea NN cord-022526-j9kg00qf 5444 13 and and CC cord-022526-j9kg00qf 5444 14 weight weight NN cord-022526-j9kg00qf 5444 15 loss loss NN cord-022526-j9kg00qf 5444 16 have have VBP cord-022526-j9kg00qf 5444 17 been be VBN cord-022526-j9kg00qf 5444 18 reported report VBN cord-022526-j9kg00qf 5444 19 . . . cord-022526-j9kg00qf 5445 1 14 14 CD cord-022526-j9kg00qf 5445 2 Foals foal NNS cord-022526-j9kg00qf 5445 3 with with IN cord-022526-j9kg00qf 5445 4 peritonitis peritonitis NN cord-022526-j9kg00qf 5445 5 usually usually RB cord-022526-j9kg00qf 5445 6 exhibit exhibit VBP cord-022526-j9kg00qf 5445 7 signs sign NNS cord-022526-j9kg00qf 5445 8 of of IN cord-022526-j9kg00qf 5445 9 colic colic NN cord-022526-j9kg00qf 5445 10 ( ( -LRB- cord-022526-j9kg00qf 5445 11 acute acute JJ cord-022526-j9kg00qf 5445 12 or or CC cord-022526-j9kg00qf 5445 13 chronic chronic JJ cord-022526-j9kg00qf 5445 14 ) ) -RRB- cord-022526-j9kg00qf 5445 15 and and CC cord-022526-j9kg00qf 5445 16 are be VBP cord-022526-j9kg00qf 5445 17 febrile febrile JJ cord-022526-j9kg00qf 5445 18 , , , cord-022526-j9kg00qf 5445 19 depressed depressed JJ cord-022526-j9kg00qf 5445 20 , , , cord-022526-j9kg00qf 5445 21 and and CC cord-022526-j9kg00qf 5445 22 inappetant inappetant NN cord-022526-j9kg00qf 5445 23 . . . cord-022526-j9kg00qf 5446 1 In in IN cord-022526-j9kg00qf 5446 2 some some DT cord-022526-j9kg00qf 5446 3 foals foal NNS cord-022526-j9kg00qf 5446 4 with with IN cord-022526-j9kg00qf 5446 5 primary primary JJ cord-022526-j9kg00qf 5446 6 peritonitis peritonitis NN cord-022526-j9kg00qf 5446 7 , , , cord-022526-j9kg00qf 5446 8 pleural pleural JJ cord-022526-j9kg00qf 5446 9 effusion effusion NN cord-022526-j9kg00qf 5446 10 occurs occur VBZ cord-022526-j9kg00qf 5446 11 . . . cord-022526-j9kg00qf 5447 1 In in IN cord-022526-j9kg00qf 5447 2 young young JJ cord-022526-j9kg00qf 5447 3 foals foal NNS cord-022526-j9kg00qf 5447 4 , , , cord-022526-j9kg00qf 5447 5 peritonitis peritonitis NN cord-022526-j9kg00qf 5447 6 can can MD cord-022526-j9kg00qf 5447 7 cause cause VB cord-022526-j9kg00qf 5447 8 rapid rapid JJ cord-022526-j9kg00qf 5447 9 metabolic metabolic JJ cord-022526-j9kg00qf 5447 10 deterioration deterioration NN cord-022526-j9kg00qf 5447 11 , , , cord-022526-j9kg00qf 5447 12 and and CC cord-022526-j9kg00qf 5447 13 determination determination NN cord-022526-j9kg00qf 5447 14 and and CC cord-022526-j9kg00qf 5447 15 correction correction NN cord-022526-j9kg00qf 5447 16 of of IN cord-022526-j9kg00qf 5447 17 the the DT cord-022526-j9kg00qf 5447 18 primary primary JJ cord-022526-j9kg00qf 5447 19 problem problem NN cord-022526-j9kg00qf 5447 20 requires require VBZ cord-022526-j9kg00qf 5447 21 immediate immediate JJ cord-022526-j9kg00qf 5447 22 attention attention NN cord-022526-j9kg00qf 5447 23 . . . cord-022526-j9kg00qf 5448 1 In in IN cord-022526-j9kg00qf 5448 2 older old JJR cord-022526-j9kg00qf 5448 3 foals foal NNS cord-022526-j9kg00qf 5448 4 , , , cord-022526-j9kg00qf 5448 5 peritonitis peritonitis NN cord-022526-j9kg00qf 5448 6 may may MD cord-022526-j9kg00qf 5448 7 occur occur VB cord-022526-j9kg00qf 5448 8 insidiously insidiously RB cord-022526-j9kg00qf 5448 9 , , , cord-022526-j9kg00qf 5448 10 as as IN cord-022526-j9kg00qf 5448 11 occurs occur VBZ cord-022526-j9kg00qf 5448 12 following follow VBG cord-022526-j9kg00qf 5448 13 S. S. NNP cord-022526-j9kg00qf 5448 14 equi equi NN cord-022526-j9kg00qf 5448 15 or or CC cord-022526-j9kg00qf 5448 16 R. R. NNP cord-022526-j9kg00qf 5448 17 equi equi JJ cord-022526-j9kg00qf 5448 18 infections infection NNS cord-022526-j9kg00qf 5448 19 . . . cord-022526-j9kg00qf 5449 1 Clinicopathologic Clinicopathologic NNP cord-022526-j9kg00qf 5449 2 abnormalities abnormality NNS cord-022526-j9kg00qf 5449 3 vary vary VBP cord-022526-j9kg00qf 5449 4 depending depend VBG cord-022526-j9kg00qf 5449 5 on on IN cord-022526-j9kg00qf 5449 6 the the DT cord-022526-j9kg00qf 5449 7 time time NN cord-022526-j9kg00qf 5449 8 of of IN cord-022526-j9kg00qf 5449 9 onset onset NN cord-022526-j9kg00qf 5449 10 and and CC cord-022526-j9kg00qf 5449 11 severity severity NN cord-022526-j9kg00qf 5449 12 of of IN cord-022526-j9kg00qf 5449 13 peritonitis peritonitis NN cord-022526-j9kg00qf 5449 14 . . . cord-022526-j9kg00qf 5450 1 Horses horse NNS cord-022526-j9kg00qf 5450 2 with with IN cord-022526-j9kg00qf 5450 3 acute acute JJ cord-022526-j9kg00qf 5450 4 , , , cord-022526-j9kg00qf 5450 5 septic septic JJ cord-022526-j9kg00qf 5450 6 peritonitis peritonitis NN cord-022526-j9kg00qf 5450 7 can can MD cord-022526-j9kg00qf 5450 8 have have VB cord-022526-j9kg00qf 5450 9 leukopenia leukopenia NN cord-022526-j9kg00qf 5450 10 , , , cord-022526-j9kg00qf 5450 11 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 5450 12 , , , cord-022526-j9kg00qf 5450 13 metabolic metabolic JJ cord-022526-j9kg00qf 5450 14 acidemia acidemia NN cord-022526-j9kg00qf 5450 15 , , , cord-022526-j9kg00qf 5450 16 azotemia azotemia NN cord-022526-j9kg00qf 5450 17 , , , cord-022526-j9kg00qf 5450 18 and and CC cord-022526-j9kg00qf 5450 19 electrolyte electrolyte NN cord-022526-j9kg00qf 5450 20 imbalances imbalance NNS cord-022526-j9kg00qf 5450 21 reflective reflective JJ cord-022526-j9kg00qf 5450 22 of of IN cord-022526-j9kg00qf 5450 23 systemic systemic JJ cord-022526-j9kg00qf 5450 24 inflammation inflammation NN cord-022526-j9kg00qf 5450 25 from from IN cord-022526-j9kg00qf 5450 26 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5450 27 and and CC cord-022526-j9kg00qf 5450 28 hypovolemia hypovolemia NN cord-022526-j9kg00qf 5450 29 . . . cord-022526-j9kg00qf 5451 1 Horses horse NNS cord-022526-j9kg00qf 5451 2 with with IN cord-022526-j9kg00qf 5451 3 peritonitis peritonitis NN cord-022526-j9kg00qf 5451 4 of of IN cord-022526-j9kg00qf 5451 5 a a DT cord-022526-j9kg00qf 5451 6 few few JJ cord-022526-j9kg00qf 5451 7 days day NNS cord-022526-j9kg00qf 5451 8 ' ' POS cord-022526-j9kg00qf 5451 9 duration duration NN cord-022526-j9kg00qf 5451 10 may may MD cord-022526-j9kg00qf 5451 11 have have VB cord-022526-j9kg00qf 5451 12 leukocytosis leukocytosis NNP cord-022526-j9kg00qf 5451 13 and and CC cord-022526-j9kg00qf 5451 14 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 5451 15 . . . cord-022526-j9kg00qf 5452 1 Plasma plasma NN cord-022526-j9kg00qf 5452 2 protein protein NN cord-022526-j9kg00qf 5452 3 levels level NNS cord-022526-j9kg00qf 5452 4 vary vary VBP cord-022526-j9kg00qf 5452 5 depending depend VBG cord-022526-j9kg00qf 5452 6 on on IN cord-022526-j9kg00qf 5452 7 the the DT cord-022526-j9kg00qf 5452 8 hydration hydration NN cord-022526-j9kg00qf 5452 9 status status NN cord-022526-j9kg00qf 5452 10 , , , cord-022526-j9kg00qf 5452 11 degree degree NN cord-022526-j9kg00qf 5452 12 of of IN cord-022526-j9kg00qf 5452 13 exudation exudation NN cord-022526-j9kg00qf 5452 14 into into IN cord-022526-j9kg00qf 5452 15 the the DT cord-022526-j9kg00qf 5452 16 peritoneum peritoneum NN cord-022526-j9kg00qf 5452 17 , , , cord-022526-j9kg00qf 5452 18 and and CC cord-022526-j9kg00qf 5452 19 type type NN cord-022526-j9kg00qf 5452 20 of of IN cord-022526-j9kg00qf 5452 21 underlying underlying JJ cord-022526-j9kg00qf 5452 22 problem problem NN cord-022526-j9kg00qf 5452 23 . . . cord-022526-j9kg00qf 5453 1 In in IN cord-022526-j9kg00qf 5453 2 chronic chronic JJ cord-022526-j9kg00qf 5453 3 peritonitis peritonitis NN cord-022526-j9kg00qf 5453 4 , , , cord-022526-j9kg00qf 5453 5 hyperproteinemia hyperproteinemia NN cord-022526-j9kg00qf 5453 6 with with IN cord-022526-j9kg00qf 5453 7 hyperglobulinemia hyperglobulinemia NNP cord-022526-j9kg00qf 5453 8 may may MD cord-022526-j9kg00qf 5453 9 be be VB cord-022526-j9kg00qf 5453 10 present present JJ cord-022526-j9kg00qf 5453 11 . . . cord-022526-j9kg00qf 5454 1 Neonates neonate NNS cord-022526-j9kg00qf 5454 2 with with IN cord-022526-j9kg00qf 5454 3 uroperitoneum uroperitoneum NN cord-022526-j9kg00qf 5454 4 caused cause VBN cord-022526-j9kg00qf 5454 5 by by IN cord-022526-j9kg00qf 5454 6 urinary urinary JJ cord-022526-j9kg00qf 5454 7 bladder bladder NN cord-022526-j9kg00qf 5454 8 rupture rupture NN cord-022526-j9kg00qf 5454 9 or or CC cord-022526-j9kg00qf 5454 10 urachal urachal NN cord-022526-j9kg00qf 5454 11 disease disease NN cord-022526-j9kg00qf 5454 12 tend tend VBP cord-022526-j9kg00qf 5454 13 to to TO cord-022526-j9kg00qf 5454 14 develop develop VB cord-022526-j9kg00qf 5454 15 azotemia azotemia NN cord-022526-j9kg00qf 5454 16 , , , cord-022526-j9kg00qf 5454 17 hyponatremia hyponatremia NN cord-022526-j9kg00qf 5454 18 , , , cord-022526-j9kg00qf 5454 19 hypochloremia hypochloremia NN cord-022526-j9kg00qf 5454 20 , , , cord-022526-j9kg00qf 5454 21 hyperkalemia hyperkalemia NN cord-022526-j9kg00qf 5454 22 , , , cord-022526-j9kg00qf 5454 23 and and CC cord-022526-j9kg00qf 5454 24 acidosis acidosis NN cord-022526-j9kg00qf 5454 25 . . . cord-022526-j9kg00qf 5455 1 Foals foal NNS cord-022526-j9kg00qf 5455 2 with with IN cord-022526-j9kg00qf 5455 3 peritonitis peritonitis NN cord-022526-j9kg00qf 5455 4 following follow VBG cord-022526-j9kg00qf 5455 5 septicemia septicemia NN cord-022526-j9kg00qf 5455 6 , , , cord-022526-j9kg00qf 5455 7 severe severe JJ cord-022526-j9kg00qf 5455 8 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5455 9 , , , cord-022526-j9kg00qf 5455 10 severe severe JJ cord-022526-j9kg00qf 5455 11 meconium meconium NN cord-022526-j9kg00qf 5455 12 impaction impaction NN cord-022526-j9kg00qf 5455 13 , , , cord-022526-j9kg00qf 5455 14 intussusception intussusception NN cord-022526-j9kg00qf 5455 15 , , , cord-022526-j9kg00qf 5455 16 small small JJ cord-022526-j9kg00qf 5455 17 intestinal intestinal JJ cord-022526-j9kg00qf 5455 18 volvulus volvulus NN cord-022526-j9kg00qf 5455 19 , , , cord-022526-j9kg00qf 5455 20 gastric gastric JJ cord-022526-j9kg00qf 5455 21 or or CC cord-022526-j9kg00qf 5455 22 duodenal duodenal JJ cord-022526-j9kg00qf 5455 23 rupture rupture NN cord-022526-j9kg00qf 5455 24 , , , cord-022526-j9kg00qf 5455 25 or or CC cord-022526-j9kg00qf 5455 26 ascarid ascarid VBN cord-022526-j9kg00qf 5456 1 impactions impaction NNS cord-022526-j9kg00qf 5456 2 usually usually RB cord-022526-j9kg00qf 5456 3 have have VBP cord-022526-j9kg00qf 5456 4 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 5456 5 findings finding NNS cord-022526-j9kg00qf 5456 6 reflective reflective JJ cord-022526-j9kg00qf 5456 7 of of IN cord-022526-j9kg00qf 5456 8 systemic systemic JJ cord-022526-j9kg00qf 5456 9 inflammation inflammation NN cord-022526-j9kg00qf 5456 10 , , , cord-022526-j9kg00qf 5456 11 such such JJ cord-022526-j9kg00qf 5456 12 as as IN cord-022526-j9kg00qf 5456 13 inflammatory inflammatory JJ cord-022526-j9kg00qf 5456 14 leukogram leukogram NN cord-022526-j9kg00qf 5456 15 or or CC cord-022526-j9kg00qf 5456 16 leukopenia leukopenia NN cord-022526-j9kg00qf 5456 17 , , , cord-022526-j9kg00qf 5456 18 hemoconcentration hemoconcentration NN cord-022526-j9kg00qf 5456 19 , , , cord-022526-j9kg00qf 5456 20 and and CC cord-022526-j9kg00qf 5456 21 acidosis acidosis NN cord-022526-j9kg00qf 5456 22 . . . cord-022526-j9kg00qf 5457 1 Chronic chronic JJ cord-022526-j9kg00qf 5457 2 abscessation abscessation NN cord-022526-j9kg00qf 5457 3 , , , cord-022526-j9kg00qf 5457 4 as as IN cord-022526-j9kg00qf 5457 5 occurs occur NNS cord-022526-j9kg00qf 5457 6 in in IN cord-022526-j9kg00qf 5457 7 foals foal NNS cord-022526-j9kg00qf 5457 8 with with IN cord-022526-j9kg00qf 5457 9 R. R. NNP cord-022526-j9kg00qf 5457 10 equi equi NN cord-022526-j9kg00qf 5457 11 and and CC cord-022526-j9kg00qf 5457 12 streptococcal streptococcal JJ cord-022526-j9kg00qf 5457 13 infections infection NNS cord-022526-j9kg00qf 5457 14 , , , cord-022526-j9kg00qf 5457 15 results result NNS cord-022526-j9kg00qf 5457 16 in in IN cord-022526-j9kg00qf 5457 17 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 5457 18 findings finding NNS cord-022526-j9kg00qf 5457 19 reflecting reflect VBG cord-022526-j9kg00qf 5457 20 chronic chronic JJ cord-022526-j9kg00qf 5457 21 inflammation inflammation NN cord-022526-j9kg00qf 5457 22 ( ( -LRB- cord-022526-j9kg00qf 5457 23 anemia anemia NN cord-022526-j9kg00qf 5457 24 , , , cord-022526-j9kg00qf 5457 25 hyperfibrinogenemia hyperfibrinogenemia NNP cord-022526-j9kg00qf 5457 26 , , , cord-022526-j9kg00qf 5457 27 hyperglobulinemia hyperglobulinemia NNP cord-022526-j9kg00qf 5457 28 ) ) -RRB- cord-022526-j9kg00qf 5457 29 . . . cord-022526-j9kg00qf 5458 1 Abnormalities abnormality NNS cord-022526-j9kg00qf 5458 2 in in IN cord-022526-j9kg00qf 5458 3 the the DT cord-022526-j9kg00qf 5458 4 composition composition NN cord-022526-j9kg00qf 5458 5 of of IN cord-022526-j9kg00qf 5458 6 peritoneal peritoneal JJ cord-022526-j9kg00qf 5458 7 fluid fluid NN cord-022526-j9kg00qf 5458 8 occur occur VBP cord-022526-j9kg00qf 5458 9 with with IN cord-022526-j9kg00qf 5458 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5458 11 inflammation inflammation NN cord-022526-j9kg00qf 5458 12 , , , cord-022526-j9kg00qf 5458 13 and and CC cord-022526-j9kg00qf 5458 14 peritoneal peritoneal JJ cord-022526-j9kg00qf 5458 15 fluid fluid NN cord-022526-j9kg00qf 5458 16 analysis analysis NN cord-022526-j9kg00qf 5458 17 is be VBZ cord-022526-j9kg00qf 5458 18 principal principal JJ cord-022526-j9kg00qf 5458 19 to to IN cord-022526-j9kg00qf 5458 20 the the DT cord-022526-j9kg00qf 5458 21 diagnosis diagnosis NN cord-022526-j9kg00qf 5458 22 of of IN cord-022526-j9kg00qf 5458 23 peritonitis peritonitis NN cord-022526-j9kg00qf 5458 24 . . . cord-022526-j9kg00qf 5459 1 One one PRP cord-022526-j9kg00qf 5459 2 collects collect VBZ cord-022526-j9kg00qf 5459 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5459 4 fluid fluid NN cord-022526-j9kg00qf 5459 5 through through IN cord-022526-j9kg00qf 5459 6 puncture puncture NN cord-022526-j9kg00qf 5459 7 of of IN cord-022526-j9kg00qf 5459 8 the the DT cord-022526-j9kg00qf 5459 9 abdomen abdomen NN cord-022526-j9kg00qf 5459 10 on on IN cord-022526-j9kg00qf 5459 11 the the DT cord-022526-j9kg00qf 5459 12 ventral ventral JJ cord-022526-j9kg00qf 5459 13 midline midline NN cord-022526-j9kg00qf 5459 14 . . . cord-022526-j9kg00qf 5460 1 One one PRP cord-022526-j9kg00qf 5460 2 should should MD cord-022526-j9kg00qf 5460 3 clip clip VB cord-022526-j9kg00qf 5460 4 and and CC cord-022526-j9kg00qf 5460 5 prepare prepare VB cord-022526-j9kg00qf 5460 6 an an DT cord-022526-j9kg00qf 5460 7 area area NN cord-022526-j9kg00qf 5460 8 aseptically aseptically RB cord-022526-j9kg00qf 5460 9 . . . cord-022526-j9kg00qf 5461 1 Usually usually RB cord-022526-j9kg00qf 5461 2 , , , cord-022526-j9kg00qf 5461 3 the the DT cord-022526-j9kg00qf 5461 4 lowest low JJS cord-022526-j9kg00qf 5461 5 point point NN cord-022526-j9kg00qf 5461 6 of of IN cord-022526-j9kg00qf 5461 7 the the DT cord-022526-j9kg00qf 5461 8 abdomen abdomen NN cord-022526-j9kg00qf 5461 9 , , , cord-022526-j9kg00qf 5461 10 5 5 CD cord-022526-j9kg00qf 5461 11 to to TO cord-022526-j9kg00qf 5461 12 10 10 CD cord-022526-j9kg00qf 5461 13 cm cm NNS cord-022526-j9kg00qf 5461 14 caudal caudal NN cord-022526-j9kg00qf 5461 15 to to IN cord-022526-j9kg00qf 5461 16 the the DT cord-022526-j9kg00qf 5461 17 xiphoid xiphoid NN cord-022526-j9kg00qf 5461 18 cartilage cartilage NN cord-022526-j9kg00qf 5461 19 , , , cord-022526-j9kg00qf 5461 20 is be VBZ cord-022526-j9kg00qf 5461 21 prepared prepare VBN cord-022526-j9kg00qf 5461 22 for for IN cord-022526-j9kg00qf 5461 23 puncture puncture NN cord-022526-j9kg00qf 5461 24 ; ; : cord-022526-j9kg00qf 5461 25 although although IN cord-022526-j9kg00qf 5461 26 in in IN cord-022526-j9kg00qf 5461 27 some some DT cord-022526-j9kg00qf 5461 28 cases case NNS cord-022526-j9kg00qf 5461 29 one one PRP cord-022526-j9kg00qf 5461 30 may may MD cord-022526-j9kg00qf 5461 31 perform perform VB cord-022526-j9kg00qf 5461 32 paracentesis paracentesi NNS cord-022526-j9kg00qf 5461 33 more more RBR cord-022526-j9kg00qf 5461 34 caudally caudally RB cord-022526-j9kg00qf 5461 35 , , , cord-022526-j9kg00qf 5461 36 particularly particularly RB cord-022526-j9kg00qf 5461 37 when when WRB cord-022526-j9kg00qf 5461 38 one one CD cord-022526-j9kg00qf 5461 39 suspects suspect VBZ cord-022526-j9kg00qf 5461 40 a a DT cord-022526-j9kg00qf 5461 41 specific specific JJ cord-022526-j9kg00qf 5461 42 area area NN cord-022526-j9kg00qf 5461 43 of of IN cord-022526-j9kg00qf 5461 44 sequestered sequester VBN cord-022526-j9kg00qf 5461 45 fluid fluid NN cord-022526-j9kg00qf 5461 46 or or CC cord-022526-j9kg00qf 5461 47 abscessation abscessation NN cord-022526-j9kg00qf 5461 48 . . . cord-022526-j9kg00qf 5462 1 In in IN cord-022526-j9kg00qf 5462 2 addition addition NN cord-022526-j9kg00qf 5462 3 , , , cord-022526-j9kg00qf 5462 4 one one PRP cord-022526-j9kg00qf 5462 5 may may MD cord-022526-j9kg00qf 5462 6 choose choose VB cord-022526-j9kg00qf 5462 7 a a DT cord-022526-j9kg00qf 5462 8 site site NN cord-022526-j9kg00qf 5462 9 to to IN cord-022526-j9kg00qf 5462 10 the the DT cord-022526-j9kg00qf 5462 11 right right NN cord-022526-j9kg00qf 5462 12 of of IN cord-022526-j9kg00qf 5462 13 midline midline NN cord-022526-j9kg00qf 5462 14 in in IN cord-022526-j9kg00qf 5462 15 an an DT cord-022526-j9kg00qf 5462 16 attempt attempt NN cord-022526-j9kg00qf 5462 17 to to TO cord-022526-j9kg00qf 5462 18 avoid avoid VB cord-022526-j9kg00qf 5462 19 the the DT cord-022526-j9kg00qf 5462 20 spleen spleen NN cord-022526-j9kg00qf 5462 21 . . . cord-022526-j9kg00qf 5463 1 One one PRP cord-022526-j9kg00qf 5463 2 can can MD cord-022526-j9kg00qf 5463 3 perform perform VB cord-022526-j9kg00qf 5463 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5463 5 puncture puncture NN cord-022526-j9kg00qf 5463 6 using use VBG cord-022526-j9kg00qf 5463 7 a a DT cord-022526-j9kg00qf 5463 8 1 1 CD cord-022526-j9kg00qf 5463 9 1 1 CD cord-022526-j9kg00qf 5463 10 / / SYM cord-022526-j9kg00qf 5463 11 2 2 CD cord-022526-j9kg00qf 5463 12 -inch -inch SYM cord-022526-j9kg00qf 5463 13 , , , cord-022526-j9kg00qf 5463 14 18-gauge 18-gauge CD cord-022526-j9kg00qf 5463 15 needle needle NN cord-022526-j9kg00qf 5463 16 or or CC cord-022526-j9kg00qf 5463 17 , , , cord-022526-j9kg00qf 5463 18 following follow VBG cord-022526-j9kg00qf 5463 19 local local JJ cord-022526-j9kg00qf 5463 20 anesthesia anesthesia NN cord-022526-j9kg00qf 5463 21 and and CC cord-022526-j9kg00qf 5463 22 a a DT cord-022526-j9kg00qf 5463 23 stab stab NN cord-022526-j9kg00qf 5463 24 incision incision NN cord-022526-j9kg00qf 5463 25 with with IN cord-022526-j9kg00qf 5463 26 a a DT cord-022526-j9kg00qf 5463 27 No no NN cord-022526-j9kg00qf 5463 28 . . NN cord-022526-j9kg00qf 5463 29 15 15 CD cord-022526-j9kg00qf 5463 30 scalpel scalpel NN cord-022526-j9kg00qf 5463 31 blade blade NN cord-022526-j9kg00qf 5463 32 , , , cord-022526-j9kg00qf 5463 33 using use VBG cord-022526-j9kg00qf 5463 34 a a DT cord-022526-j9kg00qf 5463 35 sterile sterile JJ cord-022526-j9kg00qf 5463 36 cannula cannula NN cord-022526-j9kg00qf 5463 37 . . . cord-022526-j9kg00qf 5464 1 One one PRP cord-022526-j9kg00qf 5464 2 collects collect VBZ cord-022526-j9kg00qf 5464 3 fluid fluid NN cord-022526-j9kg00qf 5464 4 by by IN cord-022526-j9kg00qf 5464 5 gravity gravity NN cord-022526-j9kg00qf 5464 6 flow flow NN cord-022526-j9kg00qf 5464 7 and and CC cord-022526-j9kg00qf 5464 8 should should MD cord-022526-j9kg00qf 5464 9 collect collect VB cord-022526-j9kg00qf 5464 10 fluid fluid NN cord-022526-j9kg00qf 5464 11 in in IN cord-022526-j9kg00qf 5464 12 a a DT cord-022526-j9kg00qf 5464 13 tube tube NN cord-022526-j9kg00qf 5464 14 containing contain VBG cord-022526-j9kg00qf 5464 15 anticoagulant anticoagulant NN cord-022526-j9kg00qf 5464 16 , , , cord-022526-j9kg00qf 5464 17 preferably preferably RB cord-022526-j9kg00qf 5464 18 EDTA EDTA NNP cord-022526-j9kg00qf 5464 19 for for IN cord-022526-j9kg00qf 5464 20 cytologic cytologic JJ cord-022526-j9kg00qf 5464 21 examination examination NN cord-022526-j9kg00qf 5464 22 , , , cord-022526-j9kg00qf 5464 23 and and CC cord-022526-j9kg00qf 5464 24 in in IN cord-022526-j9kg00qf 5464 25 a a DT cord-022526-j9kg00qf 5464 26 sterile sterile JJ cord-022526-j9kg00qf 5464 27 tube tube NN cord-022526-j9kg00qf 5464 28 without without IN cord-022526-j9kg00qf 5464 29 anticoagulant anticoagulant NN cord-022526-j9kg00qf 5464 30 for for IN cord-022526-j9kg00qf 5464 31 visual visual JJ cord-022526-j9kg00qf 5464 32 inspection inspection NN cord-022526-j9kg00qf 5464 33 and and CC cord-022526-j9kg00qf 5464 34 , , , cord-022526-j9kg00qf 5464 35 if if IN cord-022526-j9kg00qf 5464 36 desired desire VBN cord-022526-j9kg00qf 5464 37 , , , cord-022526-j9kg00qf 5464 38 for for IN cord-022526-j9kg00qf 5464 39 culture culture NN cord-022526-j9kg00qf 5464 40 . . . cord-022526-j9kg00qf 5465 1 One one PRP cord-022526-j9kg00qf 5465 2 should should MD cord-022526-j9kg00qf 5465 3 fill fill VB cord-022526-j9kg00qf 5465 4 the the DT cord-022526-j9kg00qf 5465 5 EDTA edta NN cord-022526-j9kg00qf 5465 6 tube tube NN cord-022526-j9kg00qf 5465 7 to to IN cord-022526-j9kg00qf 5465 8 half half PDT cord-022526-j9kg00qf 5465 9 its -PRON- PRP$ cord-022526-j9kg00qf 5465 10 volume volume NN cord-022526-j9kg00qf 5465 11 , , , cord-022526-j9kg00qf 5465 12 because because IN cord-022526-j9kg00qf 5465 13 the the DT cord-022526-j9kg00qf 5465 14 EDTA EDTA NNP cord-022526-j9kg00qf 5465 15 will will MD cord-022526-j9kg00qf 5465 16 alter alter VB cord-022526-j9kg00qf 5465 17 the the DT cord-022526-j9kg00qf 5465 18 refractive refractive JJ cord-022526-j9kg00qf 5465 19 index index NN cord-022526-j9kg00qf 5465 20 of of IN cord-022526-j9kg00qf 5465 21 the the DT cord-022526-j9kg00qf 5465 22 fluid fluid NN cord-022526-j9kg00qf 5465 23 , , , cord-022526-j9kg00qf 5465 24 resulting result VBG cord-022526-j9kg00qf 5465 25 in in IN cord-022526-j9kg00qf 5465 26 a a DT cord-022526-j9kg00qf 5465 27 falsely falsely RB cord-022526-j9kg00qf 5465 28 elevated elevated JJ cord-022526-j9kg00qf 5465 29 value value NN cord-022526-j9kg00qf 5465 30 for for IN cord-022526-j9kg00qf 5465 31 total total JJ cord-022526-j9kg00qf 5465 32 solids solid NNS cord-022526-j9kg00qf 5465 33 when when WRB cord-022526-j9kg00qf 5465 34 one one PRP cord-022526-j9kg00qf 5465 35 collects collect VBZ cord-022526-j9kg00qf 5465 36 only only RB cord-022526-j9kg00qf 5465 37 a a DT cord-022526-j9kg00qf 5465 38 small small JJ cord-022526-j9kg00qf 5465 39 volume volume NN cord-022526-j9kg00qf 5465 40 and and CC cord-022526-j9kg00qf 5465 41 tests test VBZ cord-022526-j9kg00qf 5465 42 it -PRON- PRP cord-022526-j9kg00qf 5465 43 with with IN cord-022526-j9kg00qf 5465 44 a a DT cord-022526-j9kg00qf 5465 45 refractometer refractometer NN cord-022526-j9kg00qf 5465 46 . . . cord-022526-j9kg00qf 5466 1 One one PRP cord-022526-j9kg00qf 5466 2 should should MD cord-022526-j9kg00qf 5466 3 evaluate evaluate VB cord-022526-j9kg00qf 5466 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5466 5 fluid fluid NN cord-022526-j9kg00qf 5466 6 routinely routinely RB cord-022526-j9kg00qf 5466 7 as as IN cord-022526-j9kg00qf 5466 8 to to TO cord-022526-j9kg00qf 5466 9 color color VB cord-022526-j9kg00qf 5466 10 , , , cord-022526-j9kg00qf 5466 11 turbidity turbidity NN cord-022526-j9kg00qf 5466 12 , , , cord-022526-j9kg00qf 5466 13 total total JJ cord-022526-j9kg00qf 5466 14 protein protein NN cord-022526-j9kg00qf 5466 15 , , , cord-022526-j9kg00qf 5466 16 white white JJ cord-022526-j9kg00qf 5466 17 blood blood NN cord-022526-j9kg00qf 5466 18 cell cell NN cord-022526-j9kg00qf 5466 19 ( ( -LRB- cord-022526-j9kg00qf 5466 20 WBC WBC NNP cord-022526-j9kg00qf 5466 21 ) ) -RRB- cord-022526-j9kg00qf 5466 22 count count VB cord-022526-j9kg00qf 5466 23 and and CC cord-022526-j9kg00qf 5466 24 differential differential NN cord-022526-j9kg00qf 5466 25 , , , cord-022526-j9kg00qf 5466 26 and and CC cord-022526-j9kg00qf 5466 27 the the DT cord-022526-j9kg00qf 5466 28 presence presence NN cord-022526-j9kg00qf 5466 29 of of IN cord-022526-j9kg00qf 5466 30 bacteria bacteria NNS cord-022526-j9kg00qf 5466 31 as as IN cord-022526-j9kg00qf 5466 32 determined determine VBN cord-022526-j9kg00qf 5466 33 by by IN cord-022526-j9kg00qf 5466 34 Gram Gram NNP cord-022526-j9kg00qf 5466 35 stain stain NN cord-022526-j9kg00qf 5466 36 . . . cord-022526-j9kg00qf 5467 1 Normal normal JJ cord-022526-j9kg00qf 5467 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5467 3 fluid fluid NN cord-022526-j9kg00qf 5467 4 is be VBZ cord-022526-j9kg00qf 5467 5 clear clear JJ cord-022526-j9kg00qf 5467 6 and and CC cord-022526-j9kg00qf 5467 7 straw straw NN cord-022526-j9kg00qf 5467 8 - - HYPH cord-022526-j9kg00qf 5467 9 colored color VBN cord-022526-j9kg00qf 5467 10 and and CC cord-022526-j9kg00qf 5467 11 does do VBZ cord-022526-j9kg00qf 5467 12 not not RB cord-022526-j9kg00qf 5467 13 coagulate coagulate VB cord-022526-j9kg00qf 5467 14 spontaneously spontaneously RB cord-022526-j9kg00qf 5467 15 . . . cord-022526-j9kg00qf 5468 1 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5468 2 fluid fluid NN cord-022526-j9kg00qf 5468 3 becomes become VBZ cord-022526-j9kg00qf 5468 4 turbid turbid JJ cord-022526-j9kg00qf 5468 5 when when WRB cord-022526-j9kg00qf 5468 6 increased increase VBN cord-022526-j9kg00qf 5468 7 numbers number NNS cord-022526-j9kg00qf 5468 8 of of IN cord-022526-j9kg00qf 5468 9 white white JJ cord-022526-j9kg00qf 5468 10 blood blood NN cord-022526-j9kg00qf 5468 11 cells cell NNS cord-022526-j9kg00qf 5468 12 and and CC cord-022526-j9kg00qf 5468 13 concentration concentration NN cord-022526-j9kg00qf 5468 14 of of IN cord-022526-j9kg00qf 5468 15 protein protein NN cord-022526-j9kg00qf 5468 16 are be VBP cord-022526-j9kg00qf 5468 17 present present JJ cord-022526-j9kg00qf 5468 18 . . . cord-022526-j9kg00qf 5469 1 Pink pink JJ cord-022526-j9kg00qf 5469 2 or or CC cord-022526-j9kg00qf 5469 3 red red JJ cord-022526-j9kg00qf 5469 4 fluid fluid NN cord-022526-j9kg00qf 5469 5 indicates indicate VBZ cord-022526-j9kg00qf 5469 6 free free JJ cord-022526-j9kg00qf 5469 7 hemoglobin hemoglobin NN cord-022526-j9kg00qf 5469 8 or or CC cord-022526-j9kg00qf 5469 9 hemorrhage hemorrhage NN cord-022526-j9kg00qf 5469 10 . . . cord-022526-j9kg00qf 5470 1 Blood blood NN cord-022526-j9kg00qf 5470 2 introduced introduce VBN cord-022526-j9kg00qf 5470 3 into into IN cord-022526-j9kg00qf 5470 4 the the DT cord-022526-j9kg00qf 5470 5 peritoneal peritoneal JJ cord-022526-j9kg00qf 5470 6 fluid fluid NN cord-022526-j9kg00qf 5470 7 iatrogenically iatrogenically RB cord-022526-j9kg00qf 5470 8 in in IN cord-022526-j9kg00qf 5470 9 some some DT cord-022526-j9kg00qf 5470 10 cases case NNS cord-022526-j9kg00qf 5470 11 may may MD cord-022526-j9kg00qf 5470 12 be be VB cord-022526-j9kg00qf 5470 13 differentiated differentiate VBN cord-022526-j9kg00qf 5470 14 from from IN cord-022526-j9kg00qf 5470 15 blood blood NN cord-022526-j9kg00qf 5470 16 from from IN cord-022526-j9kg00qf 5470 17 internal internal JJ cord-022526-j9kg00qf 5470 18 hemorrhage hemorrhage NN cord-022526-j9kg00qf 5470 19 based base VBN cord-022526-j9kg00qf 5470 20 on on IN cord-022526-j9kg00qf 5470 21 the the DT cord-022526-j9kg00qf 5470 22 presence presence NN cord-022526-j9kg00qf 5470 23 of of IN cord-022526-j9kg00qf 5470 24 platelets platelet NNS cord-022526-j9kg00qf 5470 25 and and CC cord-022526-j9kg00qf 5470 26 hematocrit hematocrit NN cord-022526-j9kg00qf 5470 27 . . . cord-022526-j9kg00qf 5471 1 Fluid fluid JJ cord-022526-j9kg00qf 5471 2 with with IN cord-022526-j9kg00qf 5471 3 iatrogenic iatrogenic JJ cord-022526-j9kg00qf 5471 4 blood blood NN cord-022526-j9kg00qf 5471 5 contamination contamination NN cord-022526-j9kg00qf 5471 6 contains contain VBZ cord-022526-j9kg00qf 5471 7 platelets platelet NNS cord-022526-j9kg00qf 5471 8 , , , cord-022526-j9kg00qf 5471 9 whereas whereas IN cord-022526-j9kg00qf 5471 10 fluid fluid NN cord-022526-j9kg00qf 5471 11 with with IN cord-022526-j9kg00qf 5471 12 blood blood NN cord-022526-j9kg00qf 5471 13 following follow VBG cord-022526-j9kg00qf 5471 14 internal internal JJ cord-022526-j9kg00qf 5471 15 hemorrhage hemorrhage NN cord-022526-j9kg00qf 5471 16 or or CC cord-022526-j9kg00qf 5471 17 diapedesis diapedesis NN cord-022526-j9kg00qf 5471 18 often often RB cord-022526-j9kg00qf 5471 19 does do VBZ cord-022526-j9kg00qf 5471 20 not not RB cord-022526-j9kg00qf 5471 21 have have VB cord-022526-j9kg00qf 5471 22 platelets platelet NNS cord-022526-j9kg00qf 5471 23 . . . cord-022526-j9kg00qf 5472 1 Blood blood NN cord-022526-j9kg00qf 5472 2 contamination contamination NN cord-022526-j9kg00qf 5472 3 resulting result VBG cord-022526-j9kg00qf 5472 4 from from IN cord-022526-j9kg00qf 5472 5 splenic splenic JJ cord-022526-j9kg00qf 5472 6 puncture puncture NN cord-022526-j9kg00qf 5472 7 often often RB cord-022526-j9kg00qf 5472 8 results result VBZ cord-022526-j9kg00qf 5472 9 in in IN cord-022526-j9kg00qf 5472 10 the the DT cord-022526-j9kg00qf 5472 11 packed packed JJ cord-022526-j9kg00qf 5472 12 cell cell NN cord-022526-j9kg00qf 5472 13 volume volume NN cord-022526-j9kg00qf 5472 14 of of IN cord-022526-j9kg00qf 5472 15 the the DT cord-022526-j9kg00qf 5472 16 sample sample NN cord-022526-j9kg00qf 5472 17 being be VBG cord-022526-j9kg00qf 5472 18 greater great JJR cord-022526-j9kg00qf 5472 19 than than IN cord-022526-j9kg00qf 5472 20 that that DT cord-022526-j9kg00qf 5472 21 of of IN cord-022526-j9kg00qf 5472 22 the the DT cord-022526-j9kg00qf 5472 23 blood blood NN cord-022526-j9kg00qf 5472 24 . . . cord-022526-j9kg00qf 5473 1 Large large JJ cord-022526-j9kg00qf 5473 2 volumes volume NNS cord-022526-j9kg00qf 5473 3 of of IN cord-022526-j9kg00qf 5473 4 dark dark JJ cord-022526-j9kg00qf 5473 5 brown brown JJ cord-022526-j9kg00qf 5473 6 or or CC cord-022526-j9kg00qf 5473 7 green green JJ cord-022526-j9kg00qf 5473 8 fluid fluid NN cord-022526-j9kg00qf 5473 9 with with IN cord-022526-j9kg00qf 5473 10 a a DT cord-022526-j9kg00qf 5473 11 fetid fetid JJ cord-022526-j9kg00qf 5473 12 odor odor NN cord-022526-j9kg00qf 5473 13 obtained obtain VBN cord-022526-j9kg00qf 5473 14 from from IN cord-022526-j9kg00qf 5473 15 several several JJ cord-022526-j9kg00qf 5473 16 sites site NNS cord-022526-j9kg00qf 5473 17 strongly strongly RB cord-022526-j9kg00qf 5473 18 suggest suggest VBP cord-022526-j9kg00qf 5473 19 bowel bowel NN cord-022526-j9kg00qf 5473 20 rupture rupture NN cord-022526-j9kg00qf 5473 21 , , , cord-022526-j9kg00qf 5473 22 but but CC cord-022526-j9kg00qf 5473 23 one one PRP cord-022526-j9kg00qf 5473 24 should should MD cord-022526-j9kg00qf 5473 25 perform perform VB cord-022526-j9kg00qf 5473 26 cytologic cytologic JJ cord-022526-j9kg00qf 5473 27 examination examination NN cord-022526-j9kg00qf 5473 28 for for IN cord-022526-j9kg00qf 5473 29 confirmation confirmation NN cord-022526-j9kg00qf 5473 30 . . . cord-022526-j9kg00qf 5474 1 The the DT cord-022526-j9kg00qf 5474 2 distribution distribution NN cord-022526-j9kg00qf 5474 3 of of IN cord-022526-j9kg00qf 5474 4 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 5474 5 and and CC cord-022526-j9kg00qf 5474 6 mononuclear mononuclear JJ cord-022526-j9kg00qf 5474 7 cells cell NNS cord-022526-j9kg00qf 5474 8 varies vary VBZ cord-022526-j9kg00qf 5474 9 widely widely RB cord-022526-j9kg00qf 5474 10 , , , cord-022526-j9kg00qf 5474 11 and and CC cord-022526-j9kg00qf 5474 12 one one PRP cord-022526-j9kg00qf 5474 13 should should MD cord-022526-j9kg00qf 5474 14 interpret interpret VB cord-022526-j9kg00qf 5474 15 the the DT cord-022526-j9kg00qf 5474 16 results result NNS cord-022526-j9kg00qf 5474 17 of of IN cord-022526-j9kg00qf 5474 18 cell cell NN cord-022526-j9kg00qf 5474 19 counts count NNS cord-022526-j9kg00qf 5474 20 and and CC cord-022526-j9kg00qf 5474 21 differentials differential NNS cord-022526-j9kg00qf 5474 22 as as IN cord-022526-j9kg00qf 5474 23 supporting support VBG cord-022526-j9kg00qf 5474 24 a a DT cord-022526-j9kg00qf 5474 25 number number NN cord-022526-j9kg00qf 5474 26 of of IN cord-022526-j9kg00qf 5474 27 disorders disorder NNS cord-022526-j9kg00qf 5474 28 rather rather RB cord-022526-j9kg00qf 5474 29 than than IN cord-022526-j9kg00qf 5474 30 a a DT cord-022526-j9kg00qf 5474 31 specific specific JJ cord-022526-j9kg00qf 5474 32 diagnosis diagnosis NN cord-022526-j9kg00qf 5474 33 . . . cord-022526-j9kg00qf 5475 1 Normal normal JJ cord-022526-j9kg00qf 5475 2 equine equine JJ cord-022526-j9kg00qf 5475 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5475 4 fluid fluid NN cord-022526-j9kg00qf 5475 5 contains contain VBZ cord-022526-j9kg00qf 5475 6 fewer few JJR cord-022526-j9kg00qf 5475 7 than than IN cord-022526-j9kg00qf 5475 8 5000 5000 CD cord-022526-j9kg00qf 5475 9 nucleated nucleated JJ cord-022526-j9kg00qf 5475 10 cells cell NNS cord-022526-j9kg00qf 5475 11 per per IN cord-022526-j9kg00qf 5475 12 microliter microliter NN cord-022526-j9kg00qf 5475 13 . . . cord-022526-j9kg00qf 5476 1 2 2 CD cord-022526-j9kg00qf 5476 2 , , , cord-022526-j9kg00qf 5476 3 15 15 CD cord-022526-j9kg00qf 5476 4 WBC WBC NNP cord-022526-j9kg00qf 5476 5 counts count NNS cord-022526-j9kg00qf 5476 6 in in IN cord-022526-j9kg00qf 5476 7 acute acute JJ cord-022526-j9kg00qf 5476 8 peritonitis peritonitis NN cord-022526-j9kg00qf 5476 9 ( ( -LRB- cord-022526-j9kg00qf 5476 10 > > NFP cord-022526-j9kg00qf 5476 11 100,000/µL 100,000/µl CD cord-022526-j9kg00qf 5476 12 ) ) -RRB- cord-022526-j9kg00qf 5476 13 are be VBP cord-022526-j9kg00qf 5476 14 reported report VBN cord-022526-j9kg00qf 5476 15 to to TO cord-022526-j9kg00qf 5476 16 be be VB cord-022526-j9kg00qf 5476 17 higher high JJR cord-022526-j9kg00qf 5476 18 than than IN cord-022526-j9kg00qf 5476 19 those those DT cord-022526-j9kg00qf 5476 20 in in IN cord-022526-j9kg00qf 5476 21 chronic chronic JJ cord-022526-j9kg00qf 5476 22 peritonitis peritonitis NN cord-022526-j9kg00qf 5476 23 ( ( -LRB- cord-022526-j9kg00qf 5476 24 20,000 20,000 CD cord-022526-j9kg00qf 5476 25 to to IN cord-022526-j9kg00qf 5476 26 60,000/µL 60,000/µl CD cord-022526-j9kg00qf 5476 27 ) ) -RRB- cord-022526-j9kg00qf 5477 1 [ [ -LRB- cord-022526-j9kg00qf 5477 2 14 14 CD cord-022526-j9kg00qf 5477 3 ] ] -RRB- cord-022526-j9kg00qf 5477 4 [ [ -LRB- cord-022526-j9kg00qf 5477 5 15 15 CD cord-022526-j9kg00qf 5477 6 ] ] -RRB- cord-022526-j9kg00qf 5477 7 [ [ -LRB- cord-022526-j9kg00qf 5477 8 16 16 CD cord-022526-j9kg00qf 5477 9 ] ] -RRB- cord-022526-j9kg00qf 5477 10 ; ; : cord-022526-j9kg00qf 5477 11 however however RB cord-022526-j9kg00qf 5477 12 , , , cord-022526-j9kg00qf 5477 13 this this DT cord-022526-j9kg00qf 5477 14 is be VBZ cord-022526-j9kg00qf 5477 15 not not RB cord-022526-j9kg00qf 5477 16 always always RB cord-022526-j9kg00qf 5477 17 the the DT cord-022526-j9kg00qf 5477 18 case case NN cord-022526-j9kg00qf 5477 19 , , , cord-022526-j9kg00qf 5477 20 and and CC cord-022526-j9kg00qf 5477 21 the the DT cord-022526-j9kg00qf 5477 22 WBC WBC NNP cord-022526-j9kg00qf 5477 23 count count NN cord-022526-j9kg00qf 5477 24 depends depend VBZ cord-022526-j9kg00qf 5477 25 most most RBS cord-022526-j9kg00qf 5477 26 on on IN cord-022526-j9kg00qf 5477 27 the the DT cord-022526-j9kg00qf 5477 28 cause cause NN cord-022526-j9kg00qf 5477 29 of of IN cord-022526-j9kg00qf 5477 30 the the DT cord-022526-j9kg00qf 5477 31 peritonitis peritonitis NN cord-022526-j9kg00qf 5477 32 . . . cord-022526-j9kg00qf 5478 1 The the DT cord-022526-j9kg00qf 5478 2 WBC WBC NNP cord-022526-j9kg00qf 5478 3 level level NN cord-022526-j9kg00qf 5478 4 does do VBZ cord-022526-j9kg00qf 5478 5 not not RB cord-022526-j9kg00qf 5478 6 always always RB cord-022526-j9kg00qf 5478 7 correlate correlate VB cord-022526-j9kg00qf 5478 8 with with IN cord-022526-j9kg00qf 5478 9 severity severity NN cord-022526-j9kg00qf 5478 10 of of IN cord-022526-j9kg00qf 5478 11 peritonitis peritonitis NN cord-022526-j9kg00qf 5478 12 or or CC cord-022526-j9kg00qf 5478 13 the the DT cord-022526-j9kg00qf 5478 14 prognosis prognosis NN cord-022526-j9kg00qf 5478 15 . . . cord-022526-j9kg00qf 5479 1 The the DT cord-022526-j9kg00qf 5479 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5479 3 fluid fluid NN cord-022526-j9kg00qf 5479 4 WBC WBC NNP cord-022526-j9kg00qf 5479 5 count count NN cord-022526-j9kg00qf 5479 6 can can MD cord-022526-j9kg00qf 5479 7 be be VB cord-022526-j9kg00qf 5479 8 greater great JJR cord-022526-j9kg00qf 5479 9 than than IN cord-022526-j9kg00qf 5479 10 100,000/µL 100,000/µl CD cord-022526-j9kg00qf 5479 11 following follow VBG cord-022526-j9kg00qf 5479 12 enterocentesis enterocentesis NN cord-022526-j9kg00qf 5479 13 , , , cord-022526-j9kg00qf 5479 14 with with IN cord-022526-j9kg00qf 5479 15 no no DT cord-022526-j9kg00qf 5479 16 clinical clinical JJ cord-022526-j9kg00qf 5479 17 signs sign NNS cord-022526-j9kg00qf 5479 18 or or CC cord-022526-j9kg00qf 5479 19 problem problem NN cord-022526-j9kg00qf 5479 20 . . . cord-022526-j9kg00qf 5480 1 17 17 CD cord-022526-j9kg00qf 5481 1 Conversely conversely RB cord-022526-j9kg00qf 5481 2 , , , cord-022526-j9kg00qf 5481 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5481 4 WBC WBC NNP cord-022526-j9kg00qf 5481 5 counts count NNS cord-022526-j9kg00qf 5481 6 of of IN cord-022526-j9kg00qf 5481 7 fewer few JJR cord-022526-j9kg00qf 5481 8 than than IN cord-022526-j9kg00qf 5481 9 100,000/µL 100,000/µl CD cord-022526-j9kg00qf 5481 10 may may MD cord-022526-j9kg00qf 5481 11 be be VB cord-022526-j9kg00qf 5481 12 found find VBN cord-022526-j9kg00qf 5481 13 in in IN cord-022526-j9kg00qf 5481 14 foals foal NNS cord-022526-j9kg00qf 5481 15 or or CC cord-022526-j9kg00qf 5481 16 horses horse NNS cord-022526-j9kg00qf 5481 17 with with IN cord-022526-j9kg00qf 5481 18 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 5481 19 abscesses abscess NNS cord-022526-j9kg00qf 5481 20 . . . cord-022526-j9kg00qf 5482 1 18 18 CD cord-022526-j9kg00qf 5483 1 The the DT cord-022526-j9kg00qf 5483 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5483 3 WBC WBC NNP cord-022526-j9kg00qf 5483 4 count count NN cord-022526-j9kg00qf 5483 5 can can MD cord-022526-j9kg00qf 5483 6 increase increase VB cord-022526-j9kg00qf 5483 7 to to IN cord-022526-j9kg00qf 5483 8 greater great JJR cord-022526-j9kg00qf 5483 9 than than IN cord-022526-j9kg00qf 5483 10 150,000/µL 150,000/µl CD cord-022526-j9kg00qf 5483 11 following follow VBG cord-022526-j9kg00qf 5483 12 celiotomy celiotomy NN cord-022526-j9kg00qf 5483 13 19 19 CD cord-022526-j9kg00qf 5483 14 and and CC cord-022526-j9kg00qf 5483 15 can can MD cord-022526-j9kg00qf 5483 16 be be VB cord-022526-j9kg00qf 5483 17 higher high JJR cord-022526-j9kg00qf 5483 18 if if IN cord-022526-j9kg00qf 5483 19 an an DT cord-022526-j9kg00qf 5483 20 enterotomy enterotomy NN cord-022526-j9kg00qf 5483 21 is be VBZ cord-022526-j9kg00qf 5483 22 done do VBN cord-022526-j9kg00qf 5483 23 . . . cord-022526-j9kg00qf 5484 1 Postoperatively postoperatively RB cord-022526-j9kg00qf 5484 2 , , , cord-022526-j9kg00qf 5484 3 the the DT cord-022526-j9kg00qf 5484 4 WBC WBC NNP cord-022526-j9kg00qf 5484 5 count count NN cord-022526-j9kg00qf 5484 6 normally normally RB cord-022526-j9kg00qf 5484 7 continues continue VBZ cord-022526-j9kg00qf 5484 8 to to TO cord-022526-j9kg00qf 5484 9 decline decline VB cord-022526-j9kg00qf 5484 10 and and CC cord-022526-j9kg00qf 5484 11 returns return NNS cord-022526-j9kg00qf 5484 12 to to IN cord-022526-j9kg00qf 5484 13 near near IN cord-022526-j9kg00qf 5484 14 normal normal JJ cord-022526-j9kg00qf 5484 15 by by IN cord-022526-j9kg00qf 5484 16 5 5 CD cord-022526-j9kg00qf 5484 17 to to TO cord-022526-j9kg00qf 5484 18 7 7 CD cord-022526-j9kg00qf 5484 19 days day NNS cord-022526-j9kg00qf 5484 20 . . . cord-022526-j9kg00qf 5485 1 Failure failure NN cord-022526-j9kg00qf 5485 2 of of IN cord-022526-j9kg00qf 5485 3 the the DT cord-022526-j9kg00qf 5485 4 WBC WBC NNP cord-022526-j9kg00qf 5485 5 count count NN cord-022526-j9kg00qf 5485 6 to to TO cord-022526-j9kg00qf 5485 7 decrease decrease VB cord-022526-j9kg00qf 5485 8 suggests suggest VBZ cord-022526-j9kg00qf 5485 9 peritonitis peritonitis NN cord-022526-j9kg00qf 5485 10 resulting result VBG cord-022526-j9kg00qf 5485 11 from from IN cord-022526-j9kg00qf 5485 12 a a DT cord-022526-j9kg00qf 5485 13 postoperative postoperative JJ cord-022526-j9kg00qf 5485 14 complication complication NN cord-022526-j9kg00qf 5485 15 . . . cord-022526-j9kg00qf 5486 1 Finally finally RB cord-022526-j9kg00qf 5486 2 , , , cord-022526-j9kg00qf 5486 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5486 4 fluid fluid NN cord-022526-j9kg00qf 5486 5 WBC WBC NNP cord-022526-j9kg00qf 5486 6 counts count VBZ cord-022526-j9kg00qf 5486 7 greater great JJR cord-022526-j9kg00qf 5486 8 than than IN cord-022526-j9kg00qf 5486 9 500,000/µL 500,000/µl CD cord-022526-j9kg00qf 5486 10 indicate indicate VBP cord-022526-j9kg00qf 5486 11 severe severe JJ cord-022526-j9kg00qf 5486 12 focal focal JJ cord-022526-j9kg00qf 5486 13 or or CC cord-022526-j9kg00qf 5486 14 generalized generalized JJ cord-022526-j9kg00qf 5486 15 peritoneal peritoneal JJ cord-022526-j9kg00qf 5486 16 sepsis sepsis NN cord-022526-j9kg00qf 5486 17 . . . cord-022526-j9kg00qf 5487 1 The the DT cord-022526-j9kg00qf 5487 2 distribution distribution NN cord-022526-j9kg00qf 5487 3 of of IN cord-022526-j9kg00qf 5487 4 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 5487 5 and and CC cord-022526-j9kg00qf 5487 6 mononuclear mononuclear JJ cord-022526-j9kg00qf 5487 7 cells cell NNS cord-022526-j9kg00qf 5487 8 varies vary VBZ cord-022526-j9kg00qf 5487 9 in in IN cord-022526-j9kg00qf 5487 10 normal normal JJ cord-022526-j9kg00qf 5487 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 5487 12 fluid fluid NN cord-022526-j9kg00qf 5487 13 , , , cord-022526-j9kg00qf 5487 14 2,15 2,15 CD cord-022526-j9kg00qf 5487 15 but but CC cord-022526-j9kg00qf 5487 16 polymorphonuclear polymorphonuclear NN cord-022526-j9kg00qf 5487 17 cells cell NNS cord-022526-j9kg00qf 5487 18 usually usually RB cord-022526-j9kg00qf 5487 19 predominate predominate VBP cord-022526-j9kg00qf 5487 20 . . . cord-022526-j9kg00qf 5488 1 With with IN cord-022526-j9kg00qf 5488 2 acute acute JJ cord-022526-j9kg00qf 5488 3 peritonitis peritonitis NN cord-022526-j9kg00qf 5488 4 , , , cord-022526-j9kg00qf 5488 5 polymorphonuclear polymorphonuclear NN cord-022526-j9kg00qf 5488 6 cells cell NNS cord-022526-j9kg00qf 5488 7 typically typically RB cord-022526-j9kg00qf 5488 8 increase increase VBP cord-022526-j9kg00qf 5488 9 to to IN cord-022526-j9kg00qf 5488 10 a a DT cord-022526-j9kg00qf 5488 11 greater great JJR cord-022526-j9kg00qf 5488 12 degree degree NN cord-022526-j9kg00qf 5488 13 than than IN cord-022526-j9kg00qf 5488 14 mononuclear mononuclear JJ cord-022526-j9kg00qf 5488 15 cells cell NNS cord-022526-j9kg00qf 5488 16 , , , cord-022526-j9kg00qf 5488 17 but but CC cord-022526-j9kg00qf 5488 18 this this DT cord-022526-j9kg00qf 5488 19 depends depend VBZ cord-022526-j9kg00qf 5488 20 on on IN cord-022526-j9kg00qf 5488 21 the the DT cord-022526-j9kg00qf 5488 22 cause cause NN cord-022526-j9kg00qf 5488 23 . . . cord-022526-j9kg00qf 5489 1 In in IN cord-022526-j9kg00qf 5489 2 horses horse NNS cord-022526-j9kg00qf 5489 3 that that WDT cord-022526-j9kg00qf 5489 4 have have VBP cord-022526-j9kg00qf 5489 5 bowel bowel NN cord-022526-j9kg00qf 5489 6 disease disease NN cord-022526-j9kg00qf 5489 7 accompanied accompany VBN cord-022526-j9kg00qf 5489 8 by by IN cord-022526-j9kg00qf 5489 9 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5489 10 , , , cord-022526-j9kg00qf 5489 11 the the DT cord-022526-j9kg00qf 5489 12 number number NN cord-022526-j9kg00qf 5489 13 of of IN cord-022526-j9kg00qf 5489 14 peritoneal peritoneal JJ cord-022526-j9kg00qf 5489 15 mononuclear mononuclear NN cord-022526-j9kg00qf 5489 16 cells cell NNS cord-022526-j9kg00qf 5489 17 increases increase VBZ cord-022526-j9kg00qf 5489 18 , , , cord-022526-j9kg00qf 5489 19 as as IN cord-022526-j9kg00qf 5489 20 does do VBZ cord-022526-j9kg00qf 5489 21 transformation transformation NN cord-022526-j9kg00qf 5489 22 of of IN cord-022526-j9kg00qf 5489 23 mesothelial mesothelial JJ cord-022526-j9kg00qf 5489 24 cells cell NNS cord-022526-j9kg00qf 5489 25 to to IN cord-022526-j9kg00qf 5489 26 macrophages macrophage NNS cord-022526-j9kg00qf 5489 27 . . . cord-022526-j9kg00qf 5490 1 In in IN cord-022526-j9kg00qf 5490 2 chronic chronic JJ cord-022526-j9kg00qf 5490 3 cases case NNS cord-022526-j9kg00qf 5490 4 , , , cord-022526-j9kg00qf 5490 5 one one CD cord-022526-j9kg00qf 5490 6 easily easily RB cord-022526-j9kg00qf 5490 7 may may MD cord-022526-j9kg00qf 5490 8 mistake mistake VB cord-022526-j9kg00qf 5490 9 transforming transform VBG cord-022526-j9kg00qf 5490 10 mesothelial mesothelial JJ cord-022526-j9kg00qf 5490 11 cells cell NNS cord-022526-j9kg00qf 5490 12 for for IN cord-022526-j9kg00qf 5490 13 neoplastic neoplastic JJ cord-022526-j9kg00qf 5490 14 cells cell NNS cord-022526-j9kg00qf 5490 15 , , , cord-022526-j9kg00qf 5490 16 which which WDT cord-022526-j9kg00qf 5490 17 can can MD cord-022526-j9kg00qf 5490 18 make make VB cord-022526-j9kg00qf 5490 19 diagnosis diagnosis NN cord-022526-j9kg00qf 5490 20 difficult difficult JJ cord-022526-j9kg00qf 5490 21 , , , cord-022526-j9kg00qf 5490 22 particularly particularly RB cord-022526-j9kg00qf 5490 23 when when WRB cord-022526-j9kg00qf 5490 24 the the DT cord-022526-j9kg00qf 5490 25 presenting present VBG cord-022526-j9kg00qf 5490 26 problem problem NN cord-022526-j9kg00qf 5490 27 is be VBZ cord-022526-j9kg00qf 5490 28 compatible compatible JJ cord-022526-j9kg00qf 5490 29 with with IN cord-022526-j9kg00qf 5490 30 a a DT cord-022526-j9kg00qf 5490 31 neoplastic neoplastic JJ cord-022526-j9kg00qf 5490 32 process process NN cord-022526-j9kg00qf 5490 33 . . . cord-022526-j9kg00qf 5491 1 In in IN cord-022526-j9kg00qf 5491 2 such such JJ cord-022526-j9kg00qf 5491 3 cases case NNS cord-022526-j9kg00qf 5491 4 , , , cord-022526-j9kg00qf 5491 5 consultation consultation NN cord-022526-j9kg00qf 5491 6 with with IN cord-022526-j9kg00qf 5491 7 a a DT cord-022526-j9kg00qf 5491 8 clinical clinical JJ cord-022526-j9kg00qf 5491 9 pathologist pathologist NN cord-022526-j9kg00qf 5491 10 regarding regard VBG cord-022526-j9kg00qf 5491 11 cytologic cytologic JJ cord-022526-j9kg00qf 5491 12 findings finding NNS cord-022526-j9kg00qf 5491 13 is be VBZ cord-022526-j9kg00qf 5491 14 prudent prudent JJ cord-022526-j9kg00qf 5491 15 . . . cord-022526-j9kg00qf 5492 1 factor factor NN cord-022526-j9kg00qf 5492 2 , , , cord-022526-j9kg00qf 5492 3 and and CC cord-022526-j9kg00qf 5492 4 interleukin-6 interleukin-6 NNP cord-022526-j9kg00qf 5492 5 have have VBP cord-022526-j9kg00qf 5492 6 been be VBN cord-022526-j9kg00qf 5492 7 measured measure VBN cord-022526-j9kg00qf 5492 8 in in IN cord-022526-j9kg00qf 5492 9 the the DT cord-022526-j9kg00qf 5492 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5492 11 fluid fluid NN cord-022526-j9kg00qf 5492 12 of of IN cord-022526-j9kg00qf 5492 13 horses horse NNS cord-022526-j9kg00qf 5492 14 with with IN cord-022526-j9kg00qf 5492 15 abdominal abdominal JJ cord-022526-j9kg00qf 5492 16 disorders disorder NNS cord-022526-j9kg00qf 5492 17 , , , cord-022526-j9kg00qf 5492 18 but but CC cord-022526-j9kg00qf 5492 19 the the DT cord-022526-j9kg00qf 5492 20 diagnostic diagnostic JJ cord-022526-j9kg00qf 5492 21 and and CC cord-022526-j9kg00qf 5492 22 prognostic prognostic JJ cord-022526-j9kg00qf 5492 23 implications implication NNS cord-022526-j9kg00qf 5492 24 of of IN cord-022526-j9kg00qf 5492 25 the the DT cord-022526-j9kg00qf 5492 26 presence presence NN cord-022526-j9kg00qf 5492 27 or or CC cord-022526-j9kg00qf 5492 28 absence absence NN cord-022526-j9kg00qf 5492 29 of of IN cord-022526-j9kg00qf 5492 30 these these DT cord-022526-j9kg00qf 5492 31 enzymes enzyme NNS cord-022526-j9kg00qf 5492 32 and and CC cord-022526-j9kg00qf 5492 33 analytes analyte NNS cord-022526-j9kg00qf 5492 34 is be VBZ cord-022526-j9kg00qf 5492 35 limited limited JJ cord-022526-j9kg00qf 5492 36 . . . cord-022526-j9kg00qf 5493 1 [ [ -LRB- cord-022526-j9kg00qf 5493 2 20 20 CD cord-022526-j9kg00qf 5493 3 ] ] -RRB- cord-022526-j9kg00qf 5493 4 [ [ -LRB- cord-022526-j9kg00qf 5493 5 21 21 CD cord-022526-j9kg00qf 5493 6 ] ] -RRB- cord-022526-j9kg00qf 5493 7 [ [ -LRB- cord-022526-j9kg00qf 5493 8 22 22 CD cord-022526-j9kg00qf 5493 9 ] ] -RRB- cord-022526-j9kg00qf 5494 1 One one PRP cord-022526-j9kg00qf 5494 2 should should MD cord-022526-j9kg00qf 5494 3 submit submit VB cord-022526-j9kg00qf 5494 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5494 5 fluid fluid JJ cord-022526-j9kg00qf 5494 6 samples sample NNS cord-022526-j9kg00qf 5494 7 in in IN cord-022526-j9kg00qf 5494 8 appropriate appropriate JJ cord-022526-j9kg00qf 5494 9 media medium NNS cord-022526-j9kg00qf 5494 10 ( ( -LRB- cord-022526-j9kg00qf 5494 11 Port Port NNP cord-022526-j9kg00qf 5494 12 - - HYPH cord-022526-j9kg00qf 5494 13 A A NNP cord-022526-j9kg00qf 5494 14 - - HYPH cord-022526-j9kg00qf 5494 15 Cul cul NN cord-022526-j9kg00qf 5494 16 Vial vial NN cord-022526-j9kg00qf 5494 17 , , , cord-022526-j9kg00qf 5494 18 BBL BBL NNP cord-022526-j9kg00qf 5494 19 Microbiology Microbiology NNP cord-022526-j9kg00qf 5494 20 System System NNP cord-022526-j9kg00qf 5494 21 ) ) -RRB- cord-022526-j9kg00qf 5494 22 for for IN cord-022526-j9kg00qf 5494 23 aerobic aerobic JJ cord-022526-j9kg00qf 5494 24 and and CC cord-022526-j9kg00qf 5494 25 anaerobic anaerobic JJ cord-022526-j9kg00qf 5494 26 cultures culture NNS cord-022526-j9kg00qf 5494 27 in in IN cord-022526-j9kg00qf 5494 28 an an DT cord-022526-j9kg00qf 5494 29 attempt attempt NN cord-022526-j9kg00qf 5494 30 to to TO cord-022526-j9kg00qf 5494 31 identify identify VB cord-022526-j9kg00qf 5494 32 the the DT cord-022526-j9kg00qf 5494 33 pathogenic pathogenic JJ cord-022526-j9kg00qf 5494 34 organism(s organism(s NNP cord-022526-j9kg00qf 5494 35 ) ) -RRB- cord-022526-j9kg00qf 5494 36 . . . cord-022526-j9kg00qf 5495 1 Obligate obligate VB cord-022526-j9kg00qf 5495 2 anaerobic anaerobic JJ cord-022526-j9kg00qf 5495 3 bacteria bacteria NNS cord-022526-j9kg00qf 5495 4 such such JJ cord-022526-j9kg00qf 5495 5 as as IN cord-022526-j9kg00qf 5495 6 Bacteroides Bacteroides NNP cord-022526-j9kg00qf 5495 7 are be VBP cord-022526-j9kg00qf 5495 8 difficult difficult JJ cord-022526-j9kg00qf 5495 9 to to TO cord-022526-j9kg00qf 5495 10 culture culture NN cord-022526-j9kg00qf 5495 11 , , , cord-022526-j9kg00qf 5495 12 because because IN cord-022526-j9kg00qf 5495 13 one one PRP cord-022526-j9kg00qf 5495 14 must must MD cord-022526-j9kg00qf 5495 15 collect collect VB cord-022526-j9kg00qf 5495 16 , , , cord-022526-j9kg00qf 5495 17 transport transport VB cord-022526-j9kg00qf 5495 18 , , , cord-022526-j9kg00qf 5495 19 and and CC cord-022526-j9kg00qf 5495 20 culture culture VB cord-022526-j9kg00qf 5495 21 the the DT cord-022526-j9kg00qf 5495 22 sample sample NN cord-022526-j9kg00qf 5495 23 under under IN cord-022526-j9kg00qf 5495 24 strict strict JJ cord-022526-j9kg00qf 5495 25 anaerobic anaerobic JJ cord-022526-j9kg00qf 5495 26 conditions condition NNS cord-022526-j9kg00qf 5495 27 . . . cord-022526-j9kg00qf 5496 1 Frequently frequently RB cord-022526-j9kg00qf 5496 2 , , , cord-022526-j9kg00qf 5496 3 bacterial bacterial JJ cord-022526-j9kg00qf 5496 4 cultures culture NNS cord-022526-j9kg00qf 5496 5 are be VBP cord-022526-j9kg00qf 5496 6 negative negative JJ cord-022526-j9kg00qf 5496 7 when when WRB cord-022526-j9kg00qf 5496 8 bacteria bacteria NNS cord-022526-j9kg00qf 5496 9 are be VBP cord-022526-j9kg00qf 5496 10 present present JJ cord-022526-j9kg00qf 5496 11 in in IN cord-022526-j9kg00qf 5496 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 5496 13 fluid fluid NN cord-022526-j9kg00qf 5496 14 . . . cord-022526-j9kg00qf 5497 1 To to TO cord-022526-j9kg00qf 5497 2 enhance enhance VB cord-022526-j9kg00qf 5497 3 recovery recovery NN cord-022526-j9kg00qf 5497 4 of of IN cord-022526-j9kg00qf 5497 5 bacteria bacteria NNS cord-022526-j9kg00qf 5497 6 , , , cord-022526-j9kg00qf 5497 7 one one PRP cord-022526-j9kg00qf 5497 8 can can MD cord-022526-j9kg00qf 5497 9 inoculate inoculate VB cord-022526-j9kg00qf 5497 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5497 11 fluid fluid NN cord-022526-j9kg00qf 5497 12 into into IN cord-022526-j9kg00qf 5497 13 blood blood NN cord-022526-j9kg00qf 5497 14 culture culture NN cord-022526-j9kg00qf 5497 15 medium medium NN cord-022526-j9kg00qf 5497 16 ( ( -LRB- cord-022526-j9kg00qf 5497 17 Septi Septi NNP cord-022526-j9kg00qf 5497 18 - - HYPH cord-022526-j9kg00qf 5497 19 Chek Chek NNP cord-022526-j9kg00qf 5497 20 Columbia Columbia NNP cord-022526-j9kg00qf 5497 21 , , , cord-022526-j9kg00qf 5497 22 Hoffmann Hoffmann NNP cord-022526-j9kg00qf 5497 23 - - HYPH cord-022526-j9kg00qf 5497 24 LaRoche LaRoche NNP cord-022526-j9kg00qf 5497 25 Inc. Inc. NNP cord-022526-j9kg00qf 5497 26 , , , cord-022526-j9kg00qf 5497 27 Nutley Nutley NNP cord-022526-j9kg00qf 5497 28 , , , cord-022526-j9kg00qf 5497 29 New New NNP cord-022526-j9kg00qf 5497 30 Jersey Jersey NNP cord-022526-j9kg00qf 5497 31 ) ) -RRB- cord-022526-j9kg00qf 5497 32 , , , cord-022526-j9kg00qf 5497 33 and and CC cord-022526-j9kg00qf 5497 34 if if IN cord-022526-j9kg00qf 5497 35 the the DT cord-022526-j9kg00qf 5497 36 horse horse NN cord-022526-j9kg00qf 5497 37 has have VBZ cord-022526-j9kg00qf 5497 38 received receive VBN cord-022526-j9kg00qf 5497 39 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5497 40 treatment treatment NN cord-022526-j9kg00qf 5497 41 , , , cord-022526-j9kg00qf 5497 42 one one CD cord-022526-j9kg00qf 5497 43 first first RB cord-022526-j9kg00qf 5497 44 should should MD cord-022526-j9kg00qf 5497 45 pass pass VB cord-022526-j9kg00qf 5497 46 fluid fluid NN cord-022526-j9kg00qf 5497 47 through through IN cord-022526-j9kg00qf 5497 48 an an DT cord-022526-j9kg00qf 5497 49 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5497 50 removal removal NN cord-022526-j9kg00qf 5497 51 device device NN cord-022526-j9kg00qf 5498 1 ( ( -LRB- cord-022526-j9kg00qf 5498 2 A.R.D. A.R.D. NNP cord-022526-j9kg00qf 5498 3 , , , cord-022526-j9kg00qf 5498 4 Becton Becton NNP cord-022526-j9kg00qf 5498 5 Dickinson Dickinson NNP cord-022526-j9kg00qf 5498 6 & & CC cord-022526-j9kg00qf 5498 7 Co. Co. NNP cord-022526-j9kg00qf 5498 8 , , , cord-022526-j9kg00qf 5498 9 Cockeysville Cockeysville NNP cord-022526-j9kg00qf 5498 10 , , , cord-022526-j9kg00qf 5498 11 Maryland Maryland NNP cord-022526-j9kg00qf 5498 12 ) ) -RRB- cord-022526-j9kg00qf 5498 13 . . . cord-022526-j9kg00qf 5499 1 Early early JJ cord-022526-j9kg00qf 5499 2 and and CC cord-022526-j9kg00qf 5499 3 aggressive aggressive JJ cord-022526-j9kg00qf 5499 4 therapy therapy NN cord-022526-j9kg00qf 5499 5 is be VBZ cord-022526-j9kg00qf 5499 6 required require VBN cord-022526-j9kg00qf 5499 7 if if IN cord-022526-j9kg00qf 5499 8 treatment treatment NN cord-022526-j9kg00qf 5499 9 of of IN cord-022526-j9kg00qf 5499 10 peritonitis peritonitis NN cord-022526-j9kg00qf 5499 11 is be VBZ cord-022526-j9kg00qf 5499 12 to to TO cord-022526-j9kg00qf 5499 13 be be VB cord-022526-j9kg00qf 5499 14 successful successful JJ cord-022526-j9kg00qf 5499 15 . . . cord-022526-j9kg00qf 5500 1 The the DT cord-022526-j9kg00qf 5500 2 goals goal NNS cord-022526-j9kg00qf 5500 3 of of IN cord-022526-j9kg00qf 5500 4 treatment treatment NN cord-022526-j9kg00qf 5500 5 are be VBP cord-022526-j9kg00qf 5500 6 to to TO cord-022526-j9kg00qf 5500 7 resolve resolve VB cord-022526-j9kg00qf 5500 8 the the DT cord-022526-j9kg00qf 5500 9 primary primary JJ cord-022526-j9kg00qf 5500 10 problem problem NN cord-022526-j9kg00qf 5500 11 , , , cord-022526-j9kg00qf 5500 12 minimize minimize VB cord-022526-j9kg00qf 5500 13 the the DT cord-022526-j9kg00qf 5500 14 inflammatory inflammatory JJ cord-022526-j9kg00qf 5500 15 response response NN cord-022526-j9kg00qf 5500 16 , , , cord-022526-j9kg00qf 5500 17 and and CC cord-022526-j9kg00qf 5500 18 prevent prevent VB cord-022526-j9kg00qf 5500 19 long long JJ cord-022526-j9kg00qf 5500 20 - - HYPH cord-022526-j9kg00qf 5500 21 term term NN cord-022526-j9kg00qf 5500 22 complications complication NNS cord-022526-j9kg00qf 5500 23 . . . cord-022526-j9kg00qf 5501 1 In in IN cord-022526-j9kg00qf 5501 2 the the DT cord-022526-j9kg00qf 5501 3 acute acute JJ cord-022526-j9kg00qf 5501 4 phase phase NN cord-022526-j9kg00qf 5501 5 , , , cord-022526-j9kg00qf 5501 6 one one PRP cord-022526-j9kg00qf 5501 7 gives give VBZ cord-022526-j9kg00qf 5501 8 primary primary JJ cord-022526-j9kg00qf 5501 9 consideration consideration NN cord-022526-j9kg00qf 5501 10 to to IN cord-022526-j9kg00qf 5501 11 the the DT cord-022526-j9kg00qf 5501 12 arrest arrest NN cord-022526-j9kg00qf 5501 13 of of IN cord-022526-j9kg00qf 5501 14 endotoxic endotoxic NNP cord-022526-j9kg00qf 5501 15 , , , cord-022526-j9kg00qf 5501 16 septic septic JJ cord-022526-j9kg00qf 5501 17 , , , cord-022526-j9kg00qf 5501 18 or or CC cord-022526-j9kg00qf 5501 19 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 5501 20 shock shock NN cord-022526-j9kg00qf 5501 21 ; ; : cord-022526-j9kg00qf 5501 22 correction correction NN cord-022526-j9kg00qf 5501 23 of of IN cord-022526-j9kg00qf 5501 24 metabolic metabolic JJ cord-022526-j9kg00qf 5501 25 and and CC cord-022526-j9kg00qf 5501 26 electrolyte electrolyte JJ cord-022526-j9kg00qf 5501 27 abnormalities abnormality NNS cord-022526-j9kg00qf 5501 28 and and CC cord-022526-j9kg00qf 5501 29 dehydration dehydration NN cord-022526-j9kg00qf 5501 30 ; ; : cord-022526-j9kg00qf 5501 31 and and CC cord-022526-j9kg00qf 5501 32 management management NN cord-022526-j9kg00qf 5501 33 of of IN cord-022526-j9kg00qf 5501 34 pain pain NN cord-022526-j9kg00qf 5501 35 . . . cord-022526-j9kg00qf 5502 1 In in IN cord-022526-j9kg00qf 5502 2 the the DT cord-022526-j9kg00qf 5502 3 absence absence NN cord-022526-j9kg00qf 5502 4 of of IN cord-022526-j9kg00qf 5502 5 blood blood NN cord-022526-j9kg00qf 5502 6 gas gas NN cord-022526-j9kg00qf 5502 7 and and CC cord-022526-j9kg00qf 5502 8 electrolyte electrolyte JJ cord-022526-j9kg00qf 5502 9 determinations determination NNS cord-022526-j9kg00qf 5502 10 , , , cord-022526-j9kg00qf 5502 11 adequate adequate JJ cord-022526-j9kg00qf 5502 12 volumes volume NNS cord-022526-j9kg00qf 5502 13 of of IN cord-022526-j9kg00qf 5502 14 a a DT cord-022526-j9kg00qf 5502 15 balanced balanced JJ cord-022526-j9kg00qf 5502 16 electrolyte electrolyte JJ cord-022526-j9kg00qf 5502 17 solution solution NN cord-022526-j9kg00qf 5502 18 are be VBP cord-022526-j9kg00qf 5502 19 required require VBN cord-022526-j9kg00qf 5502 20 to to TO cord-022526-j9kg00qf 5502 21 correct correct VB cord-022526-j9kg00qf 5502 22 dehydration dehydration NN cord-022526-j9kg00qf 5502 23 and and CC cord-022526-j9kg00qf 5502 24 support support VB cord-022526-j9kg00qf 5502 25 the the DT cord-022526-j9kg00qf 5502 26 cardiovascular cardiovascular JJ cord-022526-j9kg00qf 5502 27 system system NN cord-022526-j9kg00qf 5502 28 . . . cord-022526-j9kg00qf 5503 1 If if IN cord-022526-j9kg00qf 5503 2 the the DT cord-022526-j9kg00qf 5503 3 plasma plasma NN cord-022526-j9kg00qf 5503 4 protein protein NN cord-022526-j9kg00qf 5503 5 concentration concentration NN cord-022526-j9kg00qf 5503 6 of of IN cord-022526-j9kg00qf 5503 7 the the DT cord-022526-j9kg00qf 5503 8 horse horse NN cord-022526-j9kg00qf 5503 9 is be VBZ cord-022526-j9kg00qf 5503 10 less less JJR cord-022526-j9kg00qf 5503 11 than than IN cord-022526-j9kg00qf 5503 12 4.0 4.0 CD cord-022526-j9kg00qf 5503 13 g g NN cord-022526-j9kg00qf 5503 14 / / SYM cord-022526-j9kg00qf 5503 15 dl dl NN cord-022526-j9kg00qf 5503 16 , , , cord-022526-j9kg00qf 5503 17 one one PRP cord-022526-j9kg00qf 5503 18 should should MD cord-022526-j9kg00qf 5503 19 consider consider VB cord-022526-j9kg00qf 5503 20 administration administration NN cord-022526-j9kg00qf 5503 21 of of IN cord-022526-j9kg00qf 5503 22 plasma plasma NN cord-022526-j9kg00qf 5503 23 or or CC cord-022526-j9kg00qf 5503 24 synthetic synthetic JJ cord-022526-j9kg00qf 5503 25 colloids colloid NNS cord-022526-j9kg00qf 5503 26 . . . cord-022526-j9kg00qf 5504 1 One one PRP cord-022526-j9kg00qf 5504 2 should should MD cord-022526-j9kg00qf 5504 3 administer administer VB cord-022526-j9kg00qf 5504 4 flunixin flunixin NNP cord-022526-j9kg00qf 5504 5 meglumine meglumine FW cord-022526-j9kg00qf 5504 6 ( ( -LRB- cord-022526-j9kg00qf 5504 7 Banamine Banamine NNP cord-022526-j9kg00qf 5504 8 ) ) -RRB- cord-022526-j9kg00qf 5504 9 for for IN cord-022526-j9kg00qf 5504 10 its -PRON- PRP$ cord-022526-j9kg00qf 5504 11 local local JJ cord-022526-j9kg00qf 5504 12 and and CC cord-022526-j9kg00qf 5504 13 systemic systemic JJ cord-022526-j9kg00qf 5504 14 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5504 15 effects effect NNS cord-022526-j9kg00qf 5504 16 . . . cord-022526-j9kg00qf 5505 1 Dosages dosage NNS cord-022526-j9kg00qf 5505 2 vary vary VBP cord-022526-j9kg00qf 5505 3 depending depend VBG cord-022526-j9kg00qf 5505 4 on on IN cord-022526-j9kg00qf 5505 5 the the DT cord-022526-j9kg00qf 5505 6 severity severity NN cord-022526-j9kg00qf 5505 7 of of IN cord-022526-j9kg00qf 5505 8 peritonitis peritonitis NN cord-022526-j9kg00qf 5505 9 , , , cord-022526-j9kg00qf 5505 10 degree degree NN cord-022526-j9kg00qf 5505 11 of of IN cord-022526-j9kg00qf 5505 12 toxemia toxemia NN cord-022526-j9kg00qf 5505 13 , , , cord-022526-j9kg00qf 5505 14 severity severity NN cord-022526-j9kg00qf 5505 15 of of IN cord-022526-j9kg00qf 5505 16 pain pain NN cord-022526-j9kg00qf 5505 17 , , , cord-022526-j9kg00qf 5505 18 and and CC cord-022526-j9kg00qf 5505 19 hydration hydration NN cord-022526-j9kg00qf 5505 20 status status NN cord-022526-j9kg00qf 5505 21 of of IN cord-022526-j9kg00qf 5505 22 the the DT cord-022526-j9kg00qf 5505 23 horse horse NN cord-022526-j9kg00qf 5505 24 and and CC cord-022526-j9kg00qf 5505 25 range range VB cord-022526-j9kg00qf 5505 26 from from IN cord-022526-j9kg00qf 5505 27 0.25 0.25 CD cord-022526-j9kg00qf 5505 28 mg mg NNP cord-022526-j9kg00qf 5505 29 / / SYM cord-022526-j9kg00qf 5505 30 kg kg NNS cord-022526-j9kg00qf 5505 31 intramuscularly intramuscularly RB cord-022526-j9kg00qf 5505 32 or or CC cord-022526-j9kg00qf 5505 33 intravenously intravenously RB cord-022526-j9kg00qf 5506 1 every every DT cord-022526-j9kg00qf 5506 2 6 6 CD cord-022526-j9kg00qf 5506 3 to to TO cord-022526-j9kg00qf 5506 4 10 10 CD cord-022526-j9kg00qf 5506 5 hours hour NNS cord-022526-j9kg00qf 5506 6 to to IN cord-022526-j9kg00qf 5506 7 1.0 1.0 CD cord-022526-j9kg00qf 5506 8 mg mg NNS cord-022526-j9kg00qf 5506 9 / / SYM cord-022526-j9kg00qf 5506 10 kg kg NNS cord-022526-j9kg00qf 5506 11 intramuscularly intramuscularly RB cord-022526-j9kg00qf 5506 12 or or CC cord-022526-j9kg00qf 5506 13 intravenously intravenously RB cord-022526-j9kg00qf 5506 14 every every DT cord-022526-j9kg00qf 5506 15 12 12 CD cord-022526-j9kg00qf 5506 16 hours hour NNS cord-022526-j9kg00qf 5506 17 . . . cord-022526-j9kg00qf 5507 1 The the DT cord-022526-j9kg00qf 5507 2 higher high JJR cord-022526-j9kg00qf 5507 3 dosage dosage NN cord-022526-j9kg00qf 5507 4 provides provide VBZ cord-022526-j9kg00qf 5507 5 greater great JJR cord-022526-j9kg00qf 5507 6 visceral visceral JJ cord-022526-j9kg00qf 5507 7 analgesia analgesia NN cord-022526-j9kg00qf 5507 8 , , , cord-022526-j9kg00qf 5507 9 whereas whereas IN cord-022526-j9kg00qf 5507 10 the the DT cord-022526-j9kg00qf 5507 11 lower low JJR cord-022526-j9kg00qf 5507 12 dosage dosage NN cord-022526-j9kg00qf 5507 13 is be VBZ cord-022526-j9kg00qf 5507 14 effective effective JJ cord-022526-j9kg00qf 5507 15 in in IN cord-022526-j9kg00qf 5507 16 modifying modify VBG cord-022526-j9kg00qf 5507 17 the the DT cord-022526-j9kg00qf 5507 18 effects effect NNS cord-022526-j9kg00qf 5507 19 of of IN cord-022526-j9kg00qf 5507 20 experimental experimental JJ cord-022526-j9kg00qf 5507 21 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5507 22 . . . cord-022526-j9kg00qf 5508 1 23 23 CD cord-022526-j9kg00qf 5509 1 In in IN cord-022526-j9kg00qf 5509 2 addition addition NN cord-022526-j9kg00qf 5509 3 to to IN cord-022526-j9kg00qf 5509 4 analgesic analgesic JJ cord-022526-j9kg00qf 5509 5 and and CC cord-022526-j9kg00qf 5509 6 general general JJ cord-022526-j9kg00qf 5509 7 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5509 8 effect effect NN cord-022526-j9kg00qf 5509 9 , , , cord-022526-j9kg00qf 5509 10 flunixin flunixin NNP cord-022526-j9kg00qf 5509 11 meglumine meglumine NNP cord-022526-j9kg00qf 5509 12 may may MD cord-022526-j9kg00qf 5509 13 be be VB cord-022526-j9kg00qf 5509 14 effective effective JJ cord-022526-j9kg00qf 5509 15 in in IN cord-022526-j9kg00qf 5509 16 retarding retard VBG cord-022526-j9kg00qf 5509 17 adhesion adhesion NN cord-022526-j9kg00qf 5509 18 formation formation NN cord-022526-j9kg00qf 5509 19 when when WRB cord-022526-j9kg00qf 5509 20 administered administer VBN cord-022526-j9kg00qf 5509 21 early early RB cord-022526-j9kg00qf 5509 22 in in IN cord-022526-j9kg00qf 5509 23 the the DT cord-022526-j9kg00qf 5509 24 acute acute JJ cord-022526-j9kg00qf 5509 25 , , , cord-022526-j9kg00qf 5509 26 diffuse diffuse JJ cord-022526-j9kg00qf 5509 27 stage stage NN cord-022526-j9kg00qf 5509 28 of of IN cord-022526-j9kg00qf 5509 29 septic septic JJ cord-022526-j9kg00qf 5509 30 peritonitis peritonitis NN cord-022526-j9kg00qf 5509 31 . . . cord-022526-j9kg00qf 5510 1 2 2 LS cord-022526-j9kg00qf 5510 2 Heparin Heparin NNP cord-022526-j9kg00qf 5510 3 therapy therapy NN cord-022526-j9kg00qf 5510 4 has have VBZ cord-022526-j9kg00qf 5510 5 been be VBN cord-022526-j9kg00qf 5510 6 recommended recommend VBN cord-022526-j9kg00qf 5510 7 to to TO cord-022526-j9kg00qf 5510 8 prevent prevent VB cord-022526-j9kg00qf 5510 9 adhesion adhesion NN cord-022526-j9kg00qf 5510 10 formation formation NN cord-022526-j9kg00qf 5510 11 and and CC cord-022526-j9kg00qf 5510 12 to to TO cord-022526-j9kg00qf 5510 13 render render VB cord-022526-j9kg00qf 5510 14 bacteria bacteria NNS cord-022526-j9kg00qf 5510 15 more more RBR cord-022526-j9kg00qf 5510 16 susceptible susceptible JJ cord-022526-j9kg00qf 5510 17 to to IN cord-022526-j9kg00qf 5510 18 cellular cellular JJ cord-022526-j9kg00qf 5510 19 and and CC cord-022526-j9kg00qf 5510 20 noncellular noncellular JJ cord-022526-j9kg00qf 5510 21 clearing clearing NN cord-022526-j9kg00qf 5510 22 mechanisms mechanism NNS cord-022526-j9kg00qf 5510 23 . . . cord-022526-j9kg00qf 5511 1 In in IN cord-022526-j9kg00qf 5511 2 experimental experimental JJ cord-022526-j9kg00qf 5511 3 models model NNS cord-022526-j9kg00qf 5511 4 using use VBG cord-022526-j9kg00qf 5511 5 laboratory laboratory NN cord-022526-j9kg00qf 5511 6 animals animal NNS cord-022526-j9kg00qf 5511 7 , , , cord-022526-j9kg00qf 5511 8 Normal normal JJ cord-022526-j9kg00qf 5511 9 peritoneal peritoneal JJ cord-022526-j9kg00qf 5511 10 fluid fluid NN cord-022526-j9kg00qf 5511 11 protein protein NN cord-022526-j9kg00qf 5511 12 concentration concentration NN cord-022526-j9kg00qf 5511 13 is be VBZ cord-022526-j9kg00qf 5511 14 less less JJR cord-022526-j9kg00qf 5511 15 than than IN cord-022526-j9kg00qf 5511 16 1.5 1.5 CD cord-022526-j9kg00qf 5511 17 g g NN cord-022526-j9kg00qf 5511 18 / / SYM cord-022526-j9kg00qf 5511 19 dl dl NN cord-022526-j9kg00qf 5511 20 . . NNP cord-022526-j9kg00qf 5511 21 15 15 CD cord-022526-j9kg00qf 5511 22 Protein Protein NNP cord-022526-j9kg00qf 5511 23 levels level NNS cord-022526-j9kg00qf 5511 24 between between IN cord-022526-j9kg00qf 5511 25 1.5 1.5 CD cord-022526-j9kg00qf 5511 26 g g NN cord-022526-j9kg00qf 5511 27 / / SYM cord-022526-j9kg00qf 5511 28 dl dl NN cord-022526-j9kg00qf 5511 29 and and CC cord-022526-j9kg00qf 5511 30 2.5 2.5 CD cord-022526-j9kg00qf 5511 31 g g NN cord-022526-j9kg00qf 5511 32 / / SYM cord-022526-j9kg00qf 5511 33 dl dl NNP cord-022526-j9kg00qf 5511 34 can can MD cord-022526-j9kg00qf 5511 35 be be VB cord-022526-j9kg00qf 5511 36 difficult difficult JJ cord-022526-j9kg00qf 5511 37 to to TO cord-022526-j9kg00qf 5511 38 interpret interpret VB cord-022526-j9kg00qf 5511 39 , , , cord-022526-j9kg00qf 5511 40 but but CC cord-022526-j9kg00qf 5511 41 one one PRP cord-022526-j9kg00qf 5511 42 should should MD cord-022526-j9kg00qf 5511 43 consider consider VB cord-022526-j9kg00qf 5511 44 levels level NNS cord-022526-j9kg00qf 5511 45 greater great JJR cord-022526-j9kg00qf 5511 46 than than IN cord-022526-j9kg00qf 5511 47 2.5 2.5 CD cord-022526-j9kg00qf 5511 48 g g NN cord-022526-j9kg00qf 5511 49 / / SYM cord-022526-j9kg00qf 5511 50 dl dl NN cord-022526-j9kg00qf 5511 51 to to TO cord-022526-j9kg00qf 5511 52 be be VB cord-022526-j9kg00qf 5511 53 elevated elevate VBN cord-022526-j9kg00qf 5511 54 abnormally abnormally RB cord-022526-j9kg00qf 5511 55 . . . cord-022526-j9kg00qf 5512 1 Fibrinogen fibrinogen NN cord-022526-j9kg00qf 5512 2 concentration concentration NN cord-022526-j9kg00qf 5512 3 increases increase VBZ cord-022526-j9kg00qf 5512 4 with with IN cord-022526-j9kg00qf 5512 5 inflammation inflammation NN cord-022526-j9kg00qf 5512 6 , , , cord-022526-j9kg00qf 5512 7 and and CC cord-022526-j9kg00qf 5512 8 levels level NNS cord-022526-j9kg00qf 5512 9 greater great JJR cord-022526-j9kg00qf 5512 10 than than IN cord-022526-j9kg00qf 5512 11 10 10 CD cord-022526-j9kg00qf 5512 12 mg mg NNP cord-022526-j9kg00qf 5512 13 / / SYM cord-022526-j9kg00qf 5512 14 dl dl NN cord-022526-j9kg00qf 5512 15 in in IN cord-022526-j9kg00qf 5512 16 the the DT cord-022526-j9kg00qf 5512 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5512 18 fluid fluid NN cord-022526-j9kg00qf 5512 19 suggest suggest VBP cord-022526-j9kg00qf 5512 20 that that IN cord-022526-j9kg00qf 5512 21 an an DT cord-022526-j9kg00qf 5512 22 acute acute JJ cord-022526-j9kg00qf 5512 23 inflammatory inflammatory JJ cord-022526-j9kg00qf 5512 24 process process NN cord-022526-j9kg00qf 5512 25 is be VBZ cord-022526-j9kg00qf 5512 26 present present JJ cord-022526-j9kg00qf 5512 27 . . . cord-022526-j9kg00qf 5513 1 20 20 CD cord-022526-j9kg00qf 5513 2 Fibrinogen fibrinogen NN cord-022526-j9kg00qf 5513 3 content content NN cord-022526-j9kg00qf 5513 4 will will MD cord-022526-j9kg00qf 5513 5 also also RB cord-022526-j9kg00qf 5513 6 increase increase VB cord-022526-j9kg00qf 5513 7 from from IN cord-022526-j9kg00qf 5513 8 blood blood NN cord-022526-j9kg00qf 5513 9 contamination contamination NN cord-022526-j9kg00qf 5513 10 . . . cord-022526-j9kg00qf 5514 1 The the DT cord-022526-j9kg00qf 5514 2 presence presence NN cord-022526-j9kg00qf 5514 3 of of IN cord-022526-j9kg00qf 5514 4 free free JJ cord-022526-j9kg00qf 5514 5 and and CC cord-022526-j9kg00qf 5514 6 phagocytosed phagocytosed JJ cord-022526-j9kg00qf 5514 7 bacteria bacteria NNS cord-022526-j9kg00qf 5514 8 in in IN cord-022526-j9kg00qf 5514 9 peritoneal peritoneal JJ cord-022526-j9kg00qf 5514 10 fluid fluid NN cord-022526-j9kg00qf 5514 11 indicates indicate VBZ cord-022526-j9kg00qf 5514 12 generalized generalize VBN cord-022526-j9kg00qf 5514 13 suppuration suppuration NN cord-022526-j9kg00qf 5514 14 , , , cord-022526-j9kg00qf 5514 15 abscessation abscessation NN cord-022526-j9kg00qf 5514 16 , , , cord-022526-j9kg00qf 5514 17 or or CC cord-022526-j9kg00qf 5514 18 compromised compromised JJ cord-022526-j9kg00qf 5514 19 bowel bowel NN cord-022526-j9kg00qf 5514 20 . . . cord-022526-j9kg00qf 5515 1 If if IN cord-022526-j9kg00qf 5515 2 one one PRP cord-022526-j9kg00qf 5515 3 observes observe VBZ cord-022526-j9kg00qf 5515 4 numerous numerous JJ cord-022526-j9kg00qf 5515 5 microorganisms microorganism NNS cord-022526-j9kg00qf 5515 6 of of IN cord-022526-j9kg00qf 5515 7 mixed mixed JJ cord-022526-j9kg00qf 5515 8 types type NNS cord-022526-j9kg00qf 5515 9 free free JJ cord-022526-j9kg00qf 5515 10 in in IN cord-022526-j9kg00qf 5515 11 the the DT cord-022526-j9kg00qf 5515 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 5515 13 fluid fluid NN cord-022526-j9kg00qf 5515 14 or or CC cord-022526-j9kg00qf 5515 15 if if IN cord-022526-j9kg00qf 5515 16 one one PRP cord-022526-j9kg00qf 5515 17 observes observe VBZ cord-022526-j9kg00qf 5515 18 plant plant NN cord-022526-j9kg00qf 5515 19 material material NN cord-022526-j9kg00qf 5515 20 , , , cord-022526-j9kg00qf 5515 21 massive massive JJ cord-022526-j9kg00qf 5515 22 bacterial bacterial JJ cord-022526-j9kg00qf 5515 23 contamination contamination NN cord-022526-j9kg00qf 5515 24 of of IN cord-022526-j9kg00qf 5515 25 the the DT cord-022526-j9kg00qf 5515 26 abdomen abdomen NN cord-022526-j9kg00qf 5515 27 following follow VBG cord-022526-j9kg00qf 5515 28 bowel bowel NN cord-022526-j9kg00qf 5515 29 rupture rupture NN cord-022526-j9kg00qf 5515 30 likely likely RB cord-022526-j9kg00qf 5515 31 has have VBZ cord-022526-j9kg00qf 5515 32 occurred occur VBN cord-022526-j9kg00qf 5515 33 . . . cord-022526-j9kg00qf 5516 1 The the DT cord-022526-j9kg00qf 5516 2 presence presence NN cord-022526-j9kg00qf 5516 3 of of IN cord-022526-j9kg00qf 5516 4 toxic toxic JJ cord-022526-j9kg00qf 5516 5 or or CC cord-022526-j9kg00qf 5516 6 degenerate degenerate JJ cord-022526-j9kg00qf 5516 7 neutrophils neutrophil NNS cord-022526-j9kg00qf 5516 8 and and CC cord-022526-j9kg00qf 5516 9 bacteria bacteria NNS cord-022526-j9kg00qf 5516 10 within within IN cord-022526-j9kg00qf 5516 11 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 5516 12 cells cell NNS cord-022526-j9kg00qf 5516 13 helps help VBZ cord-022526-j9kg00qf 5516 14 to to TO cord-022526-j9kg00qf 5516 15 distinguish distinguish VB cord-022526-j9kg00qf 5516 16 peritoneal peritoneal JJ cord-022526-j9kg00qf 5516 17 fluid fluid NN cord-022526-j9kg00qf 5516 18 from from IN cord-022526-j9kg00qf 5516 19 intestinal intestinal JJ cord-022526-j9kg00qf 5516 20 contents content NNS cord-022526-j9kg00qf 5516 21 in in IN cord-022526-j9kg00qf 5516 22 such such JJ cord-022526-j9kg00qf 5516 23 cases case NNS cord-022526-j9kg00qf 5516 24 . . . cord-022526-j9kg00qf 5517 1 Enterocentesis enterocentesis NN cord-022526-j9kg00qf 5517 2 yields yield NNS cord-022526-j9kg00qf 5517 3 discolored discolor VBD cord-022526-j9kg00qf 5517 4 fluid fluid NN cord-022526-j9kg00qf 5517 5 containing contain VBG cord-022526-j9kg00qf 5517 6 mixed mix VBN cord-022526-j9kg00qf 5517 7 microorganisms microorganism NNS cord-022526-j9kg00qf 5517 8 and and CC cord-022526-j9kg00qf 5517 9 plant plant NN cord-022526-j9kg00qf 5517 10 material material NN cord-022526-j9kg00qf 5517 11 and and CC cord-022526-j9kg00qf 5517 12 that that DT cord-022526-j9kg00qf 5517 13 is be VBZ cord-022526-j9kg00qf 5517 14 largely largely RB cord-022526-j9kg00qf 5517 15 devoid devoid JJ cord-022526-j9kg00qf 5517 16 of of IN cord-022526-j9kg00qf 5517 17 white white JJ cord-022526-j9kg00qf 5517 18 blood blood NN cord-022526-j9kg00qf 5517 19 cells cell NNS cord-022526-j9kg00qf 5517 20 . . . cord-022526-j9kg00qf 5518 1 Bacterial bacterial JJ cord-022526-j9kg00qf 5518 2 contamination contamination NN cord-022526-j9kg00qf 5518 3 of of IN cord-022526-j9kg00qf 5518 4 a a DT cord-022526-j9kg00qf 5518 5 sample sample NN cord-022526-j9kg00qf 5518 6 can can MD cord-022526-j9kg00qf 5518 7 occur occur VB cord-022526-j9kg00qf 5518 8 during during IN cord-022526-j9kg00qf 5518 9 collection collection NN cord-022526-j9kg00qf 5518 10 of of IN cord-022526-j9kg00qf 5518 11 the the DT cord-022526-j9kg00qf 5518 12 sample sample NN cord-022526-j9kg00qf 5518 13 , , , cord-022526-j9kg00qf 5518 14 and and CC cord-022526-j9kg00qf 5518 15 iatrogenic iatrogenic JJ cord-022526-j9kg00qf 5518 16 contamination contamination NN cord-022526-j9kg00qf 5518 17 of of IN cord-022526-j9kg00qf 5518 18 a a DT cord-022526-j9kg00qf 5518 19 sample sample NN cord-022526-j9kg00qf 5518 20 can can MD cord-022526-j9kg00qf 5518 21 result result VB cord-022526-j9kg00qf 5518 22 in in IN cord-022526-j9kg00qf 5518 23 free free JJ cord-022526-j9kg00qf 5518 24 and and CC cord-022526-j9kg00qf 5518 25 intracellular intracellular JJ cord-022526-j9kg00qf 5518 26 bacteria bacteria NNS cord-022526-j9kg00qf 5518 27 in in IN cord-022526-j9kg00qf 5518 28 peritoneal peritoneal JJ cord-022526-j9kg00qf 5518 29 fluid fluid NN cord-022526-j9kg00qf 5518 30 , , , cord-022526-j9kg00qf 5518 31 particularly particularly RB cord-022526-j9kg00qf 5518 32 if if IN cord-022526-j9kg00qf 5518 33 processing processing NN cord-022526-j9kg00qf 5518 34 is be VBZ cord-022526-j9kg00qf 5518 35 delayed delay VBN cord-022526-j9kg00qf 5518 36 . . . cord-022526-j9kg00qf 5519 1 In in IN cord-022526-j9kg00qf 5519 2 such such JJ cord-022526-j9kg00qf 5519 3 cases case NNS cord-022526-j9kg00qf 5519 4 the the DT cord-022526-j9kg00qf 5519 5 bacterial bacterial JJ cord-022526-j9kg00qf 5519 6 numbers number NNS cord-022526-j9kg00qf 5519 7 are be VBP cord-022526-j9kg00qf 5519 8 few few JJ cord-022526-j9kg00qf 5519 9 and and CC cord-022526-j9kg00qf 5519 10 the the DT cord-022526-j9kg00qf 5519 11 neutrophils neutrophil NNS cord-022526-j9kg00qf 5519 12 appear appear VBP cord-022526-j9kg00qf 5519 13 healthy healthy JJ cord-022526-j9kg00qf 5519 14 . . . cord-022526-j9kg00qf 5520 1 In in IN cord-022526-j9kg00qf 5520 2 some some DT cord-022526-j9kg00qf 5520 3 cases case NNS cord-022526-j9kg00qf 5520 4 of of IN cord-022526-j9kg00qf 5520 5 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5520 6 perforation perforation NN cord-022526-j9kg00qf 5520 7 the the DT cord-022526-j9kg00qf 5520 8 luminal luminal JJ cord-022526-j9kg00qf 5520 9 material material NN cord-022526-j9kg00qf 5520 10 , , , cord-022526-j9kg00qf 5520 11 inflammatory inflammatory JJ cord-022526-j9kg00qf 5520 12 cells cell NNS cord-022526-j9kg00qf 5520 13 , , , cord-022526-j9kg00qf 5520 14 and and CC cord-022526-j9kg00qf 5520 15 protein protein NN cord-022526-j9kg00qf 5520 16 may may MD cord-022526-j9kg00qf 5520 17 be be VB cord-022526-j9kg00qf 5520 18 sequestered sequester VBN cord-022526-j9kg00qf 5520 19 by by IN cord-022526-j9kg00qf 5520 20 the the DT cord-022526-j9kg00qf 5520 21 omentum omentum NN cord-022526-j9kg00qf 5520 22 and and CC cord-022526-j9kg00qf 5520 23 further further RB cord-022526-j9kg00qf 5520 24 contained contain VBN cord-022526-j9kg00qf 5520 25 by by IN cord-022526-j9kg00qf 5520 26 fibrinous fibrinous JJ cord-022526-j9kg00qf 5520 27 adhesions adhesion NNS cord-022526-j9kg00qf 5520 28 . . . cord-022526-j9kg00qf 5521 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5521 2 fluid fluid NN cord-022526-j9kg00qf 5521 3 obtained obtain VBN cord-022526-j9kg00qf 5521 4 via via IN cord-022526-j9kg00qf 5521 5 standard standard JJ cord-022526-j9kg00qf 5521 6 ventral ventral JJ cord-022526-j9kg00qf 5521 7 paracentesis paracentesis NN cord-022526-j9kg00qf 5521 8 may may MD cord-022526-j9kg00qf 5521 9 have have VB cord-022526-j9kg00qf 5521 10 low low JJ cord-022526-j9kg00qf 5521 11 cellularity cellularity NN cord-022526-j9kg00qf 5521 12 and and CC cord-022526-j9kg00qf 5521 13 protein protein NN cord-022526-j9kg00qf 5521 14 content content NN cord-022526-j9kg00qf 5521 15 but but CC cord-022526-j9kg00qf 5521 16 large large JJ cord-022526-j9kg00qf 5521 17 numbers number NNS cord-022526-j9kg00qf 5521 18 of of IN cord-022526-j9kg00qf 5521 19 mixed mixed JJ cord-022526-j9kg00qf 5521 20 bacteria bacteria NNS cord-022526-j9kg00qf 5521 21 indicating indicate VBG cord-022526-j9kg00qf 5521 22 bowel bowel NN cord-022526-j9kg00qf 5521 23 rupture rupture NN cord-022526-j9kg00qf 5521 24 . . . cord-022526-j9kg00qf 5522 1 5 5 LS cord-022526-j9kg00qf 5522 2 Examples example NNS cord-022526-j9kg00qf 5522 3 include include VBP cord-022526-j9kg00qf 5522 4 gastric gastric JJ cord-022526-j9kg00qf 5522 5 rupture rupture NN cord-022526-j9kg00qf 5522 6 along along IN cord-022526-j9kg00qf 5522 7 the the DT cord-022526-j9kg00qf 5522 8 greater great JJR cord-022526-j9kg00qf 5522 9 curvature curvature NN cord-022526-j9kg00qf 5522 10 of of IN cord-022526-j9kg00qf 5522 11 the the DT cord-022526-j9kg00qf 5522 12 stomach stomach NN cord-022526-j9kg00qf 5522 13 between between IN cord-022526-j9kg00qf 5522 14 the the DT cord-022526-j9kg00qf 5522 15 omental omental JJ cord-022526-j9kg00qf 5522 16 layers layer NNS cord-022526-j9kg00qf 5522 17 ( ( -LRB- cord-022526-j9kg00qf 5522 18 omental omental NNP cord-022526-j9kg00qf 5522 19 bursa bursa NNP cord-022526-j9kg00qf 5522 20 ) ) -RRB- cord-022526-j9kg00qf 5522 21 and and CC cord-022526-j9kg00qf 5522 22 perforated perforate VBD cord-022526-j9kg00qf 5522 23 gastric gastric JJ cord-022526-j9kg00qf 5522 24 or or CC cord-022526-j9kg00qf 5522 25 duodenal duodenal JJ cord-022526-j9kg00qf 5522 26 ulcers ulcer NNS cord-022526-j9kg00qf 5522 27 in in IN cord-022526-j9kg00qf 5522 28 foals foal NNS cord-022526-j9kg00qf 5522 29 . . . cord-022526-j9kg00qf 5523 1 Correlating correlate VBG cord-022526-j9kg00qf 5523 2 all all DT cord-022526-j9kg00qf 5523 3 cytologic cytologic JJ cord-022526-j9kg00qf 5523 4 findings finding NNS cord-022526-j9kg00qf 5523 5 with with IN cord-022526-j9kg00qf 5523 6 clinical clinical JJ cord-022526-j9kg00qf 5523 7 and and CC cord-022526-j9kg00qf 5523 8 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 5523 9 findings finding NNS cord-022526-j9kg00qf 5523 10 is be VBZ cord-022526-j9kg00qf 5523 11 important important JJ cord-022526-j9kg00qf 5523 12 for for IN cord-022526-j9kg00qf 5523 13 interpreting interpret VBG cord-022526-j9kg00qf 5523 14 the the DT cord-022526-j9kg00qf 5523 15 results result NNS cord-022526-j9kg00qf 5523 16 of of IN cord-022526-j9kg00qf 5523 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5523 18 fluid fluid JJ cord-022526-j9kg00qf 5523 19 cytologic cytologic JJ cord-022526-j9kg00qf 5523 20 examination examination NN cord-022526-j9kg00qf 5523 21 . . . cord-022526-j9kg00qf 5524 1 Biochemical biochemical JJ cord-022526-j9kg00qf 5524 2 analysis analysis NN cord-022526-j9kg00qf 5524 3 of of IN cord-022526-j9kg00qf 5524 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5524 5 fluid fluid NN cord-022526-j9kg00qf 5524 6 may may MD cord-022526-j9kg00qf 5524 7 be be VB cord-022526-j9kg00qf 5524 8 useful useful JJ cord-022526-j9kg00qf 5524 9 in in IN cord-022526-j9kg00qf 5524 10 detecting detect VBG cord-022526-j9kg00qf 5524 11 sepsis sepsis NN cord-022526-j9kg00qf 5524 12 when when WRB cord-022526-j9kg00qf 5524 13 cytologic cytologic JJ cord-022526-j9kg00qf 5524 14 examination examination NN cord-022526-j9kg00qf 5524 15 and and CC cord-022526-j9kg00qf 5524 16 culture culture NN cord-022526-j9kg00qf 5524 17 are be VBP cord-022526-j9kg00qf 5524 18 negative negative JJ cord-022526-j9kg00qf 5524 19 or or CC cord-022526-j9kg00qf 5524 20 otherwise otherwise RB cord-022526-j9kg00qf 5524 21 unavailable unavailable JJ cord-022526-j9kg00qf 5524 22 . . . cord-022526-j9kg00qf 5525 1 In in IN cord-022526-j9kg00qf 5525 2 a a DT cord-022526-j9kg00qf 5525 3 prospective prospective JJ cord-022526-j9kg00qf 5525 4 study study NN cord-022526-j9kg00qf 5525 5 by by IN cord-022526-j9kg00qf 5525 6 Van Van NNP cord-022526-j9kg00qf 5525 7 Hoogmoed Hoogmoed NNP cord-022526-j9kg00qf 5525 8 , , , cord-022526-j9kg00qf 5525 9 Rodger Rodger NNP cord-022526-j9kg00qf 5525 10 , , , cord-022526-j9kg00qf 5525 11 Spier Spier NNP cord-022526-j9kg00qf 5525 12 , , , cord-022526-j9kg00qf 5525 13 et et NNP cord-022526-j9kg00qf 5525 14 al al NNP cord-022526-j9kg00qf 5525 15 . . NNP cord-022526-j9kg00qf 5525 16 , , , cord-022526-j9kg00qf 5525 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5525 18 fluid fluid NN cord-022526-j9kg00qf 5525 19 pH ph NN cord-022526-j9kg00qf 5525 20 and and CC cord-022526-j9kg00qf 5525 21 glucose glucose NN cord-022526-j9kg00qf 5525 22 concentrations concentration NNS cord-022526-j9kg00qf 5525 23 from from IN cord-022526-j9kg00qf 5525 24 horses horse NNS cord-022526-j9kg00qf 5525 25 with with IN cord-022526-j9kg00qf 5525 26 septic septic JJ cord-022526-j9kg00qf 5525 27 peritonitis peritonitis NN cord-022526-j9kg00qf 5525 28 were be VBD cord-022526-j9kg00qf 5525 29 significantly significantly RB cord-022526-j9kg00qf 5525 30 lower low JJR cord-022526-j9kg00qf 5525 31 than than IN cord-022526-j9kg00qf 5525 32 horses horse NNS cord-022526-j9kg00qf 5525 33 with with IN cord-022526-j9kg00qf 5525 34 nonseptic nonseptic JJ cord-022526-j9kg00qf 5525 35 peritonitis peritonitis NN cord-022526-j9kg00qf 5525 36 and and CC cord-022526-j9kg00qf 5525 37 healthy healthy JJ cord-022526-j9kg00qf 5525 38 horses horse NNS cord-022526-j9kg00qf 5525 39 . . . cord-022526-j9kg00qf 5526 1 21 21 CD cord-022526-j9kg00qf 5526 2 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5526 3 fluid fluid NN cord-022526-j9kg00qf 5526 4 pH ph NN cord-022526-j9kg00qf 5526 5 less less JJR cord-022526-j9kg00qf 5526 6 than than IN cord-022526-j9kg00qf 5526 7 7.3 7.3 CD cord-022526-j9kg00qf 5526 8 , , , cord-022526-j9kg00qf 5526 9 glucose glucose NN cord-022526-j9kg00qf 5526 10 less less JJR cord-022526-j9kg00qf 5526 11 than than IN cord-022526-j9kg00qf 5526 12 30 30 CD cord-022526-j9kg00qf 5526 13 mg mg NNP cord-022526-j9kg00qf 5526 14 / / SYM cord-022526-j9kg00qf 5526 15 dl dl NNP cord-022526-j9kg00qf 5526 16 , , , cord-022526-j9kg00qf 5526 17 and and CC cord-022526-j9kg00qf 5526 18 fibrinogen fibrinogen NN cord-022526-j9kg00qf 5526 19 concentration concentration NN cord-022526-j9kg00qf 5527 1 greater great JJR cord-022526-j9kg00qf 5527 2 than than IN cord-022526-j9kg00qf 5527 3 200 200 CD cord-022526-j9kg00qf 5527 4 mg mg NNP cord-022526-j9kg00qf 5527 5 / / SYM cord-022526-j9kg00qf 5527 6 dl dl NNP cord-022526-j9kg00qf 5527 7 were be VBD cord-022526-j9kg00qf 5527 8 considered consider VBN cord-022526-j9kg00qf 5527 9 highly highly RB cord-022526-j9kg00qf 5527 10 predictive predictive JJ cord-022526-j9kg00qf 5527 11 of of IN cord-022526-j9kg00qf 5527 12 septic septic JJ cord-022526-j9kg00qf 5527 13 peritonitis peritonitis NN cord-022526-j9kg00qf 5527 14 . . . cord-022526-j9kg00qf 5528 1 Serum serum NN cord-022526-j9kg00qf 5528 2 to to IN cord-022526-j9kg00qf 5528 3 peritoneal peritoneal JJ cord-022526-j9kg00qf 5528 4 glucose glucose NN cord-022526-j9kg00qf 5528 5 concentration concentration NN cord-022526-j9kg00qf 5528 6 differences difference NNS cord-022526-j9kg00qf 5528 7 of of IN cord-022526-j9kg00qf 5528 8 greater great JJR cord-022526-j9kg00qf 5528 9 than than IN cord-022526-j9kg00qf 5528 10 50 50 CD cord-022526-j9kg00qf 5528 11 mg mg NNP cord-022526-j9kg00qf 5528 12 / / SYM cord-022526-j9kg00qf 5528 13 dl dl NNP cord-022526-j9kg00qf 5528 14 was be VBD cord-022526-j9kg00qf 5528 15 considered consider VBN cord-022526-j9kg00qf 5528 16 the the DT cord-022526-j9kg00qf 5528 17 most most RBS cord-022526-j9kg00qf 5528 18 diagnostically diagnostically RB cord-022526-j9kg00qf 5528 19 useful useful JJ cord-022526-j9kg00qf 5528 20 test test NN cord-022526-j9kg00qf 5528 21 for for IN cord-022526-j9kg00qf 5528 22 septic septic JJ cord-022526-j9kg00qf 5528 23 peritonitis peritonitis NN cord-022526-j9kg00qf 5528 24 in in IN cord-022526-j9kg00qf 5528 25 the the DT cord-022526-j9kg00qf 5528 26 study study NN cord-022526-j9kg00qf 5528 27 . . . cord-022526-j9kg00qf 5529 1 Increased increase VBN cord-022526-j9kg00qf 5529 2 activities activity NNS cord-022526-j9kg00qf 5529 3 of of IN cord-022526-j9kg00qf 5529 4 alkaline alkaline JJ cord-022526-j9kg00qf 5529 5 phosphatase phosphatase NN cord-022526-j9kg00qf 5529 6 , , , cord-022526-j9kg00qf 5529 7 lactic lactic JJ cord-022526-j9kg00qf 5529 8 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 5529 9 , , , cord-022526-j9kg00qf 5529 10 creatine creatine NN cord-022526-j9kg00qf 5529 11 kinase kinase NN cord-022526-j9kg00qf 5529 12 , , , cord-022526-j9kg00qf 5529 13 aspartate aspartate NN cord-022526-j9kg00qf 5529 14 aminotransferase aminotransferase NN cord-022526-j9kg00qf 5529 15 , , , cord-022526-j9kg00qf 5529 16 tumor tumor NN cord-022526-j9kg00qf 5529 17 necrosis necrosis NN cord-022526-j9kg00qf 5529 18 heparin heparin NN cord-022526-j9kg00qf 5529 19 therapy therapy NN cord-022526-j9kg00qf 5529 20 was be VBD cord-022526-j9kg00qf 5529 21 associated associate VBN cord-022526-j9kg00qf 5529 22 with with IN cord-022526-j9kg00qf 5529 23 decreased decreased JJ cord-022526-j9kg00qf 5529 24 adhesions adhesion NNS cord-022526-j9kg00qf 5529 25 in in IN cord-022526-j9kg00qf 5529 26 septic septic JJ cord-022526-j9kg00qf 5529 27 peritonitis peritonitis NN cord-022526-j9kg00qf 5529 28 . . . cord-022526-j9kg00qf 5530 1 24 24 CD cord-022526-j9kg00qf 5530 2 Heparin Heparin NNP cord-022526-j9kg00qf 5530 3 has have VBZ cord-022526-j9kg00qf 5530 4 not not RB cord-022526-j9kg00qf 5530 5 yet yet RB cord-022526-j9kg00qf 5530 6 been be VBN cord-022526-j9kg00qf 5530 7 demonstrated demonstrate VBN cord-022526-j9kg00qf 5530 8 clearly clearly RB cord-022526-j9kg00qf 5530 9 to to TO cord-022526-j9kg00qf 5530 10 have have VB cord-022526-j9kg00qf 5530 11 similar similar JJ cord-022526-j9kg00qf 5530 12 efficacy efficacy NN cord-022526-j9kg00qf 5530 13 in in IN cord-022526-j9kg00qf 5530 14 horses horse NNS cord-022526-j9kg00qf 5530 15 , , , cord-022526-j9kg00qf 5530 16 although although IN cord-022526-j9kg00qf 5530 17 it -PRON- PRP cord-022526-j9kg00qf 5530 18 may may MD cord-022526-j9kg00qf 5530 19 . . . cord-022526-j9kg00qf 5531 1 Suggested suggest VBN cord-022526-j9kg00qf 5531 2 dosages dosage NNS cord-022526-j9kg00qf 5531 3 range range VBP cord-022526-j9kg00qf 5531 4 from from IN cord-022526-j9kg00qf 5531 5 20 20 CD cord-022526-j9kg00qf 5531 6 to to TO cord-022526-j9kg00qf 5531 7 40 40 CD cord-022526-j9kg00qf 5531 8 IU IU NNP cord-022526-j9kg00qf 5531 9 subcutaneously subcutaneously RB cord-022526-j9kg00qf 5531 10 every every DT cord-022526-j9kg00qf 5531 11 12 12 CD cord-022526-j9kg00qf 5531 12 hours hour NNS cord-022526-j9kg00qf 5531 13 for for IN cord-022526-j9kg00qf 5531 14 48 48 CD cord-022526-j9kg00qf 5531 15 hours hour NNS cord-022526-j9kg00qf 5531 16 4 4 CD cord-022526-j9kg00qf 5531 17 to to IN cord-022526-j9kg00qf 5531 18 40 40 CD cord-022526-j9kg00qf 5531 19 to to TO cord-022526-j9kg00qf 5531 20 80 80 CD cord-022526-j9kg00qf 5531 21 IU IU NNP cord-022526-j9kg00qf 5531 22 / / SYM cord-022526-j9kg00qf 5531 23 kg kg CC cord-022526-j9kg00qf 5531 24 subcutaneously subcutaneously RB cord-022526-j9kg00qf 5531 25 every every DT cord-022526-j9kg00qf 5531 26 8 8 CD cord-022526-j9kg00qf 5531 27 hours hour NNS cord-022526-j9kg00qf 5531 28 . . . cord-022526-j9kg00qf 5532 1 5 5 LS cord-022526-j9kg00qf 5533 1 One one PRP cord-022526-j9kg00qf 5533 2 should should MD cord-022526-j9kg00qf 5533 3 note note VB cord-022526-j9kg00qf 5533 4 that that IN cord-022526-j9kg00qf 5533 5 heparin heparin NN cord-022526-j9kg00qf 5533 6 induces induce VBZ cord-022526-j9kg00qf 5533 7 red red JJ cord-022526-j9kg00qf 5533 8 blood blood NN cord-022526-j9kg00qf 5533 9 cell cell NN cord-022526-j9kg00qf 5533 10 aggregation aggregation NN cord-022526-j9kg00qf 5533 11 in in IN cord-022526-j9kg00qf 5533 12 horses horse NNS cord-022526-j9kg00qf 5533 13 , , , cord-022526-j9kg00qf 5533 14 25 25 CD cord-022526-j9kg00qf 5533 15 which which WDT cord-022526-j9kg00qf 5533 16 may may MD cord-022526-j9kg00qf 5533 17 adversely adversely RB cord-022526-j9kg00qf 5533 18 affect affect VB cord-022526-j9kg00qf 5533 19 capillary capillary JJ cord-022526-j9kg00qf 5533 20 blood blood NN cord-022526-j9kg00qf 5533 21 flow flow NN cord-022526-j9kg00qf 5533 22 . . . cord-022526-j9kg00qf 5534 1 One one PRP cord-022526-j9kg00qf 5534 2 should should MD cord-022526-j9kg00qf 5534 3 initiate initiate VB cord-022526-j9kg00qf 5534 4 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5534 5 therapy therapy NN cord-022526-j9kg00qf 5534 6 after after IN cord-022526-j9kg00qf 5534 7 making make VBG cord-022526-j9kg00qf 5534 8 a a DT cord-022526-j9kg00qf 5534 9 diagnosis diagnosis NN cord-022526-j9kg00qf 5534 10 of of IN cord-022526-j9kg00qf 5534 11 peritonitis peritonitis NN cord-022526-j9kg00qf 5534 12 and and CC cord-022526-j9kg00qf 5534 13 before before IN cord-022526-j9kg00qf 5534 14 the the DT cord-022526-j9kg00qf 5534 15 results result NNS cord-022526-j9kg00qf 5534 16 of of IN cord-022526-j9kg00qf 5534 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5534 18 culture culture NN cord-022526-j9kg00qf 5534 19 are be VBP cord-022526-j9kg00qf 5534 20 available available JJ cord-022526-j9kg00qf 5534 21 , , , cord-022526-j9kg00qf 5534 22 because because IN cord-022526-j9kg00qf 5534 23 isolating isolate VBG cord-022526-j9kg00qf 5534 24 an an DT cord-022526-j9kg00qf 5534 25 organism organism NN cord-022526-j9kg00qf 5534 26 may may MD cord-022526-j9kg00qf 5534 27 take take VB cord-022526-j9kg00qf 5534 28 several several JJ cord-022526-j9kg00qf 5534 29 days day NNS cord-022526-j9kg00qf 5534 30 and and CC cord-022526-j9kg00qf 5534 31 often often RB cord-022526-j9kg00qf 5534 32 culture culture NN cord-022526-j9kg00qf 5534 33 fails fail VBZ cord-022526-j9kg00qf 5534 34 to to TO cord-022526-j9kg00qf 5534 35 isolate isolate VB cord-022526-j9kg00qf 5534 36 the the DT cord-022526-j9kg00qf 5534 37 organism(s organism(s NNP cord-022526-j9kg00qf 5534 38 ) ) -RRB- cord-022526-j9kg00qf 5534 39 . . . cord-022526-j9kg00qf 5535 1 Intravenous intravenous JJ cord-022526-j9kg00qf 5535 2 administration administration NN cord-022526-j9kg00qf 5535 3 of of IN cord-022526-j9kg00qf 5535 4 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 5535 5 is be VBZ cord-022526-j9kg00qf 5535 6 preferred prefer VBN cord-022526-j9kg00qf 5535 7 over over IN cord-022526-j9kg00qf 5535 8 oral oral JJ cord-022526-j9kg00qf 5535 9 or or CC cord-022526-j9kg00qf 5535 10 intramuscular intramuscular JJ cord-022526-j9kg00qf 5535 11 routes route NNS cord-022526-j9kg00qf 5535 12 in in IN cord-022526-j9kg00qf 5535 13 acute acute JJ cord-022526-j9kg00qf 5535 14 , , , cord-022526-j9kg00qf 5535 15 diffuse diffuse JJ cord-022526-j9kg00qf 5535 16 , , , cord-022526-j9kg00qf 5535 17 septic septic JJ cord-022526-j9kg00qf 5535 18 peritonitis peritonitis NN cord-022526-j9kg00qf 5535 19 because because IN cord-022526-j9kg00qf 5535 20 more more RBR cord-022526-j9kg00qf 5535 21 reliable reliable JJ cord-022526-j9kg00qf 5535 22 levels level NNS cord-022526-j9kg00qf 5535 23 of of IN cord-022526-j9kg00qf 5535 24 drug drug NN cord-022526-j9kg00qf 5535 25 are be VBP cord-022526-j9kg00qf 5535 26 achieved achieve VBN cord-022526-j9kg00qf 5535 27 in in IN cord-022526-j9kg00qf 5535 28 the the DT cord-022526-j9kg00qf 5535 29 tissues tissue NNS cord-022526-j9kg00qf 5535 30 and and CC cord-022526-j9kg00qf 5535 31 peritoneal peritoneal JJ cord-022526-j9kg00qf 5535 32 fluid fluid NN cord-022526-j9kg00qf 5535 33 than than IN cord-022526-j9kg00qf 5535 34 otherwise otherwise RB cord-022526-j9kg00qf 5535 35 would would MD cord-022526-j9kg00qf 5535 36 be be VB cord-022526-j9kg00qf 5535 37 obtained obtain VBN cord-022526-j9kg00qf 5535 38 in in IN cord-022526-j9kg00qf 5535 39 horses horse NNS cord-022526-j9kg00qf 5535 40 with with IN cord-022526-j9kg00qf 5535 41 hypovolemia hypovolemia NN cord-022526-j9kg00qf 5535 42 or or CC cord-022526-j9kg00qf 5535 43 decreased decrease VBD cord-022526-j9kg00qf 5535 44 intestinal intestinal JJ cord-022526-j9kg00qf 5535 45 motility motility NN cord-022526-j9kg00qf 5535 46 . . . cord-022526-j9kg00qf 5536 1 26 26 CD cord-022526-j9kg00qf 5537 1 The the DT cord-022526-j9kg00qf 5537 2 combination combination NN cord-022526-j9kg00qf 5537 3 of of IN cord-022526-j9kg00qf 5537 4 a a DT cord-022526-j9kg00qf 5537 5 β β NN cord-022526-j9kg00qf 5537 6 - - HYPH cord-022526-j9kg00qf 5537 7 lactam lactam NNS cord-022526-j9kg00qf 5537 8 antibiotic antibiotic NN cord-022526-j9kg00qf 5537 9 with with IN cord-022526-j9kg00qf 5537 10 an an DT cord-022526-j9kg00qf 5537 11 aminoglycoside aminoglycoside NN cord-022526-j9kg00qf 5537 12 is be VBZ cord-022526-j9kg00qf 5537 13 appropriate appropriate JJ cord-022526-j9kg00qf 5537 14 in in IN cord-022526-j9kg00qf 5537 15 most most JJS cord-022526-j9kg00qf 5537 16 circumstances circumstance NNS cord-022526-j9kg00qf 5537 17 and and CC cord-022526-j9kg00qf 5537 18 certainly certainly RB cord-022526-j9kg00qf 5537 19 in in IN cord-022526-j9kg00qf 5537 20 the the DT cord-022526-j9kg00qf 5537 21 acute acute JJ cord-022526-j9kg00qf 5537 22 diffuse diffuse JJ cord-022526-j9kg00qf 5537 23 stage stage NN cord-022526-j9kg00qf 5537 24 of of IN cord-022526-j9kg00qf 5537 25 septic septic JJ cord-022526-j9kg00qf 5537 26 peritonitis peritonitis NN cord-022526-j9kg00qf 5537 27 . . . cord-022526-j9kg00qf 5538 1 These these DT cord-022526-j9kg00qf 5538 2 drugs drug NNS cord-022526-j9kg00qf 5538 3 act act VBP cord-022526-j9kg00qf 5538 4 synergistically synergistically RB cord-022526-j9kg00qf 5538 5 to to TO cord-022526-j9kg00qf 5538 6 provide provide VB cord-022526-j9kg00qf 5538 7 a a DT cord-022526-j9kg00qf 5538 8 broad broad JJ cord-022526-j9kg00qf 5538 9 spectrum spectrum NN cord-022526-j9kg00qf 5538 10 of of IN cord-022526-j9kg00qf 5538 11 activity activity NN cord-022526-j9kg00qf 5538 12 against against IN cord-022526-j9kg00qf 5538 13 a a DT cord-022526-j9kg00qf 5538 14 variety variety NN cord-022526-j9kg00qf 5538 15 of of IN cord-022526-j9kg00qf 5538 16 gram gram NN cord-022526-j9kg00qf 5538 17 - - HYPH cord-022526-j9kg00qf 5538 18 positive positive JJ cord-022526-j9kg00qf 5538 19 and and CC cord-022526-j9kg00qf 5538 20 gramnegative gramnegative JJ cord-022526-j9kg00qf 5538 21 aerobic aerobic JJ cord-022526-j9kg00qf 5538 22 and and CC cord-022526-j9kg00qf 5538 23 anaerobic anaerobic JJ cord-022526-j9kg00qf 5538 24 bacteria bacteria NNS cord-022526-j9kg00qf 5538 25 . . . cord-022526-j9kg00qf 5539 1 27 27 CD cord-022526-j9kg00qf 5540 1 Potassium potassium NN cord-022526-j9kg00qf 5540 2 penicillin penicillin NN cord-022526-j9kg00qf 5541 1 ( ( -LRB- cord-022526-j9kg00qf 5541 2 22,000 22,000 CD cord-022526-j9kg00qf 5541 3 to to TO cord-022526-j9kg00qf 5541 4 44,000 44,000 CD cord-022526-j9kg00qf 5541 5 IU IU NNP cord-022526-j9kg00qf 5541 6 / / SYM cord-022526-j9kg00qf 5541 7 kg kg CC cord-022526-j9kg00qf 5541 8 intravenously intravenously RB cord-022526-j9kg00qf 5541 9 every every DT cord-022526-j9kg00qf 5541 10 6 6 CD cord-022526-j9kg00qf 5541 11 hours hour NNS cord-022526-j9kg00qf 5541 12 ) ) -RRB- cord-022526-j9kg00qf 5541 13 combined combine VBN cord-022526-j9kg00qf 5541 14 with with IN cord-022526-j9kg00qf 5541 15 gentamicin gentamicin NNS cord-022526-j9kg00qf 5541 16 ( ( -LRB- cord-022526-j9kg00qf 5541 17 6.6 6.6 CD cord-022526-j9kg00qf 5541 18 mg mg NNP cord-022526-j9kg00qf 5541 19 / / SYM cord-022526-j9kg00qf 5541 20 kg kg NN cord-022526-j9kg00qf 5541 21 every every DT cord-022526-j9kg00qf 5541 22 24 24 CD cord-022526-j9kg00qf 5541 23 hours hour NNS cord-022526-j9kg00qf 5541 24 ) ) -RRB- cord-022526-j9kg00qf 5541 25 is be VBZ cord-022526-j9kg00qf 5541 26 an an DT cord-022526-j9kg00qf 5541 27 appropriate appropriate JJ cord-022526-j9kg00qf 5541 28 regimen regimen NN cord-022526-j9kg00qf 5541 29 . . . cord-022526-j9kg00qf 5542 1 In in IN cord-022526-j9kg00qf 5542 2 most most JJS cord-022526-j9kg00qf 5542 3 cases case NNS cord-022526-j9kg00qf 5542 4 , , , cord-022526-j9kg00qf 5542 5 peritonitis peritonitis NN cord-022526-j9kg00qf 5542 6 will will MD cord-022526-j9kg00qf 5542 7 have have VB cord-022526-j9kg00qf 5542 8 resulted result VBN cord-022526-j9kg00qf 5542 9 from from IN cord-022526-j9kg00qf 5542 10 bowel bowel NN cord-022526-j9kg00qf 5542 11 contamination contamination NN cord-022526-j9kg00qf 5542 12 , , , cord-022526-j9kg00qf 5542 13 and and CC cord-022526-j9kg00qf 5542 14 thus thus RB cord-022526-j9kg00qf 5542 15 one one PRP cord-022526-j9kg00qf 5542 16 should should MD cord-022526-j9kg00qf 5542 17 presume presume VB cord-022526-j9kg00qf 5542 18 a a DT cord-022526-j9kg00qf 5542 19 mixed mixed JJ cord-022526-j9kg00qf 5542 20 infection infection NN cord-022526-j9kg00qf 5542 21 with with IN cord-022526-j9kg00qf 5542 22 gram gram JJ cord-022526-j9kg00qf 5542 23 - - HYPH cord-022526-j9kg00qf 5542 24 negative negative JJ cord-022526-j9kg00qf 5542 25 aerobic aerobic JJ cord-022526-j9kg00qf 5542 26 bacteria bacteria NNS cord-022526-j9kg00qf 5542 27 and and CC cord-022526-j9kg00qf 5542 28 gram gram NN cord-022526-j9kg00qf 5542 29 - - HYPH cord-022526-j9kg00qf 5542 30 positive positive JJ cord-022526-j9kg00qf 5542 31 and and CC cord-022526-j9kg00qf 5542 32 gram gram JJ cord-022526-j9kg00qf 5542 33 - - HYPH cord-022526-j9kg00qf 5542 34 negative negative JJ cord-022526-j9kg00qf 5542 35 anaerobic anaerobic JJ cord-022526-j9kg00qf 5542 36 bacteria bacteria NNS cord-022526-j9kg00qf 5542 37 . . . cord-022526-j9kg00qf 5543 1 2 2 LS cord-022526-j9kg00qf 5544 1 One one CD cord-022526-j9kg00qf 5544 2 also also RB cord-022526-j9kg00qf 5544 3 should should MD cord-022526-j9kg00qf 5544 4 presume presume VB cord-022526-j9kg00qf 5544 5 the the DT cord-022526-j9kg00qf 5544 6 same same JJ cord-022526-j9kg00qf 5544 7 in in IN cord-022526-j9kg00qf 5544 8 many many JJ cord-022526-j9kg00qf 5544 9 cases case NNS cord-022526-j9kg00qf 5544 10 of of IN cord-022526-j9kg00qf 5544 11 traumatic traumatic JJ cord-022526-j9kg00qf 5544 12 peritonitis peritonitis NN cord-022526-j9kg00qf 5544 13 , , , cord-022526-j9kg00qf 5544 14 as as IN cord-022526-j9kg00qf 5544 15 occurs occur VBZ cord-022526-j9kg00qf 5544 16 with with IN cord-022526-j9kg00qf 5544 17 foreign foreign JJ cord-022526-j9kg00qf 5544 18 body body NN cord-022526-j9kg00qf 5544 19 puncture puncture NN cord-022526-j9kg00qf 5544 20 , , , cord-022526-j9kg00qf 5544 21 breeding breed VBG cord-022526-j9kg00qf 5544 22 trauma trauma NN cord-022526-j9kg00qf 5544 23 , , , cord-022526-j9kg00qf 5544 24 or or CC cord-022526-j9kg00qf 5544 25 foaling foal VBG cord-022526-j9kg00qf 5544 26 trauma trauma NN cord-022526-j9kg00qf 5544 27 . . . cord-022526-j9kg00qf 5545 1 Therefore therefore RB cord-022526-j9kg00qf 5545 2 a a DT cord-022526-j9kg00qf 5545 3 strong strong JJ cord-022526-j9kg00qf 5545 4 possibility possibility NN cord-022526-j9kg00qf 5545 5 exists exist VBZ cord-022526-j9kg00qf 5545 6 of of IN cord-022526-j9kg00qf 5545 7 infection infection NN cord-022526-j9kg00qf 5545 8 involving involve VBG cord-022526-j9kg00qf 5545 9 penicillin penicillin NN cord-022526-j9kg00qf 5545 10 resistant resistant JJ cord-022526-j9kg00qf 5545 11 Bacteroides Bacteroides NNP cord-022526-j9kg00qf 5545 12 fragilis fragili NNS cord-022526-j9kg00qf 5545 13 , , , cord-022526-j9kg00qf 5545 14 so so IN cord-022526-j9kg00qf 5545 15 that that IN cord-022526-j9kg00qf 5545 16 adding add VBG cord-022526-j9kg00qf 5545 17 metronidazole metronidazole NNP cord-022526-j9kg00qf 5545 18 ( ( -LRB- cord-022526-j9kg00qf 5545 19 15 15 CD cord-022526-j9kg00qf 5545 20 mg mg NNP cord-022526-j9kg00qf 5545 21 / / SYM cord-022526-j9kg00qf 5545 22 kg kg CC cord-022526-j9kg00qf 5545 23 orally orally RB cord-022526-j9kg00qf 5545 24 every every DT cord-022526-j9kg00qf 5545 25 6 6 CD cord-022526-j9kg00qf 5545 26 to to TO cord-022526-j9kg00qf 5545 27 8 8 CD cord-022526-j9kg00qf 5545 28 hours hour NNS cord-022526-j9kg00qf 5545 29 ) ) -RRB- cord-022526-j9kg00qf 5545 30 to to IN cord-022526-j9kg00qf 5545 31 the the DT cord-022526-j9kg00qf 5545 32 regimen regimen NN cord-022526-j9kg00qf 5545 33 is be VBZ cord-022526-j9kg00qf 5545 34 prudent prudent JJ cord-022526-j9kg00qf 5545 35 . . . cord-022526-j9kg00qf 5546 1 Combination combination NN cord-022526-j9kg00qf 5546 2 therapy therapy NN cord-022526-j9kg00qf 5546 3 with with IN cord-022526-j9kg00qf 5546 4 β β NN cord-022526-j9kg00qf 5546 5 - - HYPH cord-022526-j9kg00qf 5546 6 lactam lactam NNP cord-022526-j9kg00qf 5546 7 and and CC cord-022526-j9kg00qf 5546 8 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 5546 9 antibiotics antibiotic NNS cord-022526-j9kg00qf 5546 10 ( ( -LRB- cord-022526-j9kg00qf 5546 11 and and CC cord-022526-j9kg00qf 5546 12 metronidazole metronidazole NNP cord-022526-j9kg00qf 5546 13 when when WRB cord-022526-j9kg00qf 5546 14 indicated indicate VBN cord-022526-j9kg00qf 5546 15 ) ) -RRB- cord-022526-j9kg00qf 5546 16 is be VBZ cord-022526-j9kg00qf 5546 17 a a DT cord-022526-j9kg00qf 5546 18 standard standard NN cord-022526-j9kg00qf 5546 19 and and CC cord-022526-j9kg00qf 5546 20 generally generally RB cord-022526-j9kg00qf 5546 21 effective effective JJ cord-022526-j9kg00qf 5546 22 protocol protocol NN cord-022526-j9kg00qf 5546 23 . . . cord-022526-j9kg00qf 5547 1 One one PRP cord-022526-j9kg00qf 5547 2 can can MD cord-022526-j9kg00qf 5547 3 modify modify VB cord-022526-j9kg00qf 5547 4 this this DT cord-022526-j9kg00qf 5547 5 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5547 6 regimen regimen NN cord-022526-j9kg00qf 5547 7 when when WRB cord-022526-j9kg00qf 5547 8 culture culture NN cord-022526-j9kg00qf 5547 9 and and CC cord-022526-j9kg00qf 5547 10 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5547 11 sensitivity sensitivity NN cord-022526-j9kg00qf 5547 12 results result NNS cord-022526-j9kg00qf 5547 13 become become VBN cord-022526-j9kg00qf 5547 14 available available JJ cord-022526-j9kg00qf 5547 15 . . . cord-022526-j9kg00qf 5548 1 Aminoglycosides aminoglycoside NNS cord-022526-j9kg00qf 5548 2 and and CC cord-022526-j9kg00qf 5548 3 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5548 4 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5548 5 drugs drug NNS cord-022526-j9kg00qf 5548 6 have have VBP cord-022526-j9kg00qf 5548 7 the the DT cord-022526-j9kg00qf 5548 8 potential potential NN cord-022526-j9kg00qf 5548 9 to to TO cord-022526-j9kg00qf 5548 10 induce induce VB cord-022526-j9kg00qf 5548 11 acute acute JJ cord-022526-j9kg00qf 5548 12 renal renal JJ cord-022526-j9kg00qf 5548 13 tubular tubular JJ cord-022526-j9kg00qf 5548 14 damage damage NN cord-022526-j9kg00qf 5548 15 , , , cord-022526-j9kg00qf 5548 16 particularly particularly RB cord-022526-j9kg00qf 5548 17 when when WRB cord-022526-j9kg00qf 5548 18 dehydration dehydration NN cord-022526-j9kg00qf 5548 19 and and CC cord-022526-j9kg00qf 5548 20 decreased decrease VBD cord-022526-j9kg00qf 5548 21 renal renal JJ cord-022526-j9kg00qf 5548 22 perfusion perfusion NN cord-022526-j9kg00qf 5548 23 are be VBP cord-022526-j9kg00qf 5548 24 present present JJ cord-022526-j9kg00qf 5548 25 . . . cord-022526-j9kg00qf 5549 1 Therefore therefore RB cord-022526-j9kg00qf 5549 2 adequately adequately RB cord-022526-j9kg00qf 5549 3 rehydrating rehydrate VBG cord-022526-j9kg00qf 5549 4 the the DT cord-022526-j9kg00qf 5549 5 patient patient NN cord-022526-j9kg00qf 5549 6 and and CC cord-022526-j9kg00qf 5549 7 ensuring ensure VBG cord-022526-j9kg00qf 5549 8 that that IN cord-022526-j9kg00qf 5549 9 renal renal JJ cord-022526-j9kg00qf 5549 10 function function NN cord-022526-j9kg00qf 5549 11 is be VBZ cord-022526-j9kg00qf 5549 12 intact intact JJ cord-022526-j9kg00qf 5549 13 before before IN cord-022526-j9kg00qf 5549 14 initiating initiate VBG cord-022526-j9kg00qf 5549 15 treatment treatment NN cord-022526-j9kg00qf 5549 16 with with IN cord-022526-j9kg00qf 5549 17 these these DT cord-022526-j9kg00qf 5549 18 drugs drug NNS cord-022526-j9kg00qf 5549 19 are be VBP cord-022526-j9kg00qf 5549 20 important important JJ cord-022526-j9kg00qf 5549 21 . . . cord-022526-j9kg00qf 5550 1 Furthermore furthermore RB cord-022526-j9kg00qf 5550 2 , , , cord-022526-j9kg00qf 5550 3 maintaining maintain VBG cord-022526-j9kg00qf 5550 4 hydration hydration NN cord-022526-j9kg00qf 5550 5 and and CC cord-022526-j9kg00qf 5550 6 monitoring monitor VBG cord-022526-j9kg00qf 5550 7 renal renal JJ cord-022526-j9kg00qf 5550 8 function function NN cord-022526-j9kg00qf 5550 9 during during IN cord-022526-j9kg00qf 5550 10 the the DT cord-022526-j9kg00qf 5550 11 course course NN cord-022526-j9kg00qf 5550 12 of of IN cord-022526-j9kg00qf 5550 13 treatment treatment NN cord-022526-j9kg00qf 5550 14 are be VBP cord-022526-j9kg00qf 5550 15 important important JJ cord-022526-j9kg00qf 5550 16 . . . cord-022526-j9kg00qf 5551 1 Monitoring monitor VBG cord-022526-j9kg00qf 5551 2 serum serum NN cord-022526-j9kg00qf 5551 3 creatinine creatinine NN cord-022526-j9kg00qf 5551 4 concentration concentration NN cord-022526-j9kg00qf 5551 5 ; ; : cord-022526-j9kg00qf 5551 6 performing perform VBG cord-022526-j9kg00qf 5551 7 serial serial JJ cord-022526-j9kg00qf 5551 8 uninalysis uninalysis NN cord-022526-j9kg00qf 5551 9 observing observe VBG cord-022526-j9kg00qf 5551 10 for for IN cord-022526-j9kg00qf 5551 11 pigment pigment NN cord-022526-j9kg00qf 5551 12 , , , cord-022526-j9kg00qf 5551 13 red red JJ cord-022526-j9kg00qf 5551 14 blood blood NN cord-022526-j9kg00qf 5551 15 cells cell NNS cord-022526-j9kg00qf 5551 16 ; ; : cord-022526-j9kg00qf 5551 17 and and CC cord-022526-j9kg00qf 5551 18 casts cast VBZ cord-022526-j9kg00qf 5551 19 ; ; : cord-022526-j9kg00qf 5551 20 determining determine VBG cord-022526-j9kg00qf 5551 21 the the DT cord-022526-j9kg00qf 5551 22 ratio ratio NN cord-022526-j9kg00qf 5551 23 of of IN cord-022526-j9kg00qf 5551 24 γ γ NN cord-022526-j9kg00qf 5551 25 - - HYPH cord-022526-j9kg00qf 5551 26 glutamyltransferase glutamyltransferase NNP cord-022526-j9kg00qf 5551 27 to to IN cord-022526-j9kg00qf 5551 28 creatinine creatinine NN cord-022526-j9kg00qf 5551 29 in in IN cord-022526-j9kg00qf 5551 30 the the DT cord-022526-j9kg00qf 5551 31 urine urine NN cord-022526-j9kg00qf 5551 32 ; ; : cord-022526-j9kg00qf 5551 33 and and CC cord-022526-j9kg00qf 5551 34 therapeutic therapeutic JJ cord-022526-j9kg00qf 5551 35 drug drug NN cord-022526-j9kg00qf 5551 36 monitoring monitor VBG cord-022526-j9kg00qf 5551 37 26 26 CD cord-022526-j9kg00qf 5551 38 of of IN cord-022526-j9kg00qf 5551 39 aminoglycoside aminoglycoside JJ cord-022526-j9kg00qf 5551 40 levels level NNS cord-022526-j9kg00qf 5551 41 are be VBP cord-022526-j9kg00qf 5551 42 useful useful JJ cord-022526-j9kg00qf 5551 43 in in IN cord-022526-j9kg00qf 5551 44 this this DT cord-022526-j9kg00qf 5551 45 regard regard NN cord-022526-j9kg00qf 5551 46 . . . cord-022526-j9kg00qf 5552 1 Sodium sodium NN cord-022526-j9kg00qf 5552 2 ampicillin ampicillin NN cord-022526-j9kg00qf 5552 3 and and CC cord-022526-j9kg00qf 5552 4 ceftiofur ceftiofur JJ cord-022526-j9kg00qf 5552 5 sodium sodium NN cord-022526-j9kg00qf 5552 6 are be VBP cord-022526-j9kg00qf 5553 1 β β NN cord-022526-j9kg00qf 5553 2 - - HYPH cord-022526-j9kg00qf 5553 3 lactam lactam NNP cord-022526-j9kg00qf 5553 4 antibiotics antibiotic NNS cord-022526-j9kg00qf 5553 5 that that WDT cord-022526-j9kg00qf 5553 6 may may MD cord-022526-j9kg00qf 5553 7 be be VB cord-022526-j9kg00qf 5553 8 useful useful JJ cord-022526-j9kg00qf 5553 9 in in IN cord-022526-j9kg00qf 5553 10 combination combination NN cord-022526-j9kg00qf 5553 11 therapy therapy NN cord-022526-j9kg00qf 5553 12 . . . cord-022526-j9kg00qf 5554 1 These these DT cord-022526-j9kg00qf 5554 2 drugs drug NNS cord-022526-j9kg00qf 5554 3 have have VBP cord-022526-j9kg00qf 5554 4 an an DT cord-022526-j9kg00qf 5554 5 extended extend VBN cord-022526-j9kg00qf 5554 6 gram gram NN cord-022526-j9kg00qf 5554 7 - - HYPH cord-022526-j9kg00qf 5554 8 negative negative JJ cord-022526-j9kg00qf 5554 9 spectrum spectrum NN cord-022526-j9kg00qf 5554 10 compared compare VBN cord-022526-j9kg00qf 5554 11 with with IN cord-022526-j9kg00qf 5554 12 penicillin penicillin NN cord-022526-j9kg00qf 5554 13 . . . cord-022526-j9kg00qf 5555 1 However however RB cord-022526-j9kg00qf 5555 2 , , , cord-022526-j9kg00qf 5555 3 as as IN cord-022526-j9kg00qf 5555 4 a a DT cord-022526-j9kg00qf 5555 5 third third JJ cord-022526-j9kg00qf 5555 6 - - HYPH cord-022526-j9kg00qf 5555 7 generation generation NN cord-022526-j9kg00qf 5555 8 cephalosporin cephalosporin NN cord-022526-j9kg00qf 5555 9 , , , cord-022526-j9kg00qf 5555 10 ceftiofur ceftiofur NNP cord-022526-j9kg00qf 5555 11 is be VBZ cord-022526-j9kg00qf 5555 12 less less RBR cord-022526-j9kg00qf 5555 13 effective effective JJ cord-022526-j9kg00qf 5555 14 against against IN cord-022526-j9kg00qf 5555 15 anaerobes anaerobe NNS cord-022526-j9kg00qf 5555 16 than than IN cord-022526-j9kg00qf 5555 17 penicillin penicillin NN cord-022526-j9kg00qf 5555 18 . . . cord-022526-j9kg00qf 5556 1 One one CD cord-022526-j9kg00qf 5556 2 also also RB cord-022526-j9kg00qf 5556 3 may may MD cord-022526-j9kg00qf 5556 4 consider consider VB cord-022526-j9kg00qf 5556 5 ceftiofur ceftiofur JJ cord-022526-j9kg00qf 5556 6 , , , cord-022526-j9kg00qf 5556 7 trimethoprim trimethoprim NN cord-022526-j9kg00qf 5556 8 - - HYPH cord-022526-j9kg00qf 5556 9 potentiated potentiate VBN cord-022526-j9kg00qf 5556 10 sulfonamides sulfonamide NNS cord-022526-j9kg00qf 5556 11 , , , cord-022526-j9kg00qf 5556 12 amikacin amikacin NNS cord-022526-j9kg00qf 5556 13 , , , cord-022526-j9kg00qf 5556 14 and and CC cord-022526-j9kg00qf 5556 15 enrofloxacin enrofloxacin NNS cord-022526-j9kg00qf 5556 16 for for IN cord-022526-j9kg00qf 5556 17 treatment treatment NN cord-022526-j9kg00qf 5556 18 of of IN cord-022526-j9kg00qf 5556 19 gram gram NN cord-022526-j9kg00qf 5556 20 - - HYPH cord-022526-j9kg00qf 5556 21 negative negative JJ cord-022526-j9kg00qf 5556 22 infection infection NN cord-022526-j9kg00qf 5556 23 based base VBN cord-022526-j9kg00qf 5556 24 on on IN cord-022526-j9kg00qf 5556 25 culture culture NN cord-022526-j9kg00qf 5556 26 and and CC cord-022526-j9kg00qf 5556 27 sensitivity sensitivity NN cord-022526-j9kg00qf 5556 28 results result NNS cord-022526-j9kg00qf 5556 29 . . . cord-022526-j9kg00qf 5557 1 Enrofloxacin Enrofloxacin NNP cord-022526-j9kg00qf 5557 2 is be VBZ cord-022526-j9kg00qf 5557 3 a a DT cord-022526-j9kg00qf 5557 4 quinolone quinolone NNP cord-022526-j9kg00qf 5557 5 drug drug NN cord-022526-j9kg00qf 5557 6 with with IN cord-022526-j9kg00qf 5557 7 excellent excellent JJ cord-022526-j9kg00qf 5557 8 activity activity NN cord-022526-j9kg00qf 5557 9 against against IN cord-022526-j9kg00qf 5557 10 gramnegative gramnegative JJ cord-022526-j9kg00qf 5557 11 pathogens pathogen NNS cord-022526-j9kg00qf 5557 12 , , , cord-022526-j9kg00qf 5557 13 including include VBG cord-022526-j9kg00qf 5557 14 Pseudomonas Pseudomonas NNP cord-022526-j9kg00qf 5557 15 , , , cord-022526-j9kg00qf 5557 16 27 27 CD cord-022526-j9kg00qf 5557 17 and and CC cord-022526-j9kg00qf 5557 18 also also RB cord-022526-j9kg00qf 5557 19 can can MD cord-022526-j9kg00qf 5557 20 be be VB cord-022526-j9kg00qf 5557 21 effective effective JJ cord-022526-j9kg00qf 5557 22 against against IN cord-022526-j9kg00qf 5557 23 resistant resistant JJ cord-022526-j9kg00qf 5557 24 staphylococci staphylococcus NNS cord-022526-j9kg00qf 5557 25 ( ( -LRB- cord-022526-j9kg00qf 5557 26 personal personal JJ cord-022526-j9kg00qf 5557 27 observation observation NN cord-022526-j9kg00qf 5557 28 ) ) -RRB- cord-022526-j9kg00qf 5557 29 . . . cord-022526-j9kg00qf 5558 1 Such such JJ cord-022526-j9kg00qf 5558 2 staphylococci staphylococcus NNS cord-022526-j9kg00qf 5558 3 may may MD cord-022526-j9kg00qf 5558 4 be be VB cord-022526-j9kg00qf 5558 5 involved involve VBN cord-022526-j9kg00qf 5558 6 in in IN cord-022526-j9kg00qf 5558 7 infections infection NNS cord-022526-j9kg00qf 5558 8 caused cause VBN cord-022526-j9kg00qf 5558 9 by by IN cord-022526-j9kg00qf 5558 10 traumatic traumatic JJ cord-022526-j9kg00qf 5558 11 puncture puncture NN cord-022526-j9kg00qf 5558 12 of of IN cord-022526-j9kg00qf 5558 13 the the DT cord-022526-j9kg00qf 5558 14 abdominal abdominal JJ cord-022526-j9kg00qf 5558 15 wall wall NN cord-022526-j9kg00qf 5558 16 . . . cord-022526-j9kg00qf 5559 1 Enrofloxacin Enrofloxacin NNP cord-022526-j9kg00qf 5559 2 has have VBZ cord-022526-j9kg00qf 5559 3 a a DT cord-022526-j9kg00qf 5559 4 variety variety NN cord-022526-j9kg00qf 5559 5 of of IN cord-022526-j9kg00qf 5559 6 potential potential JJ cord-022526-j9kg00qf 5559 7 toxic toxic JJ cord-022526-j9kg00qf 5559 8 effects effect NNS cord-022526-j9kg00qf 5559 9 , , , cord-022526-j9kg00qf 5559 10 including include VBG cord-022526-j9kg00qf 5559 11 cartilage cartilage NN cord-022526-j9kg00qf 5559 12 damage damage NN cord-022526-j9kg00qf 5559 13 in in IN cord-022526-j9kg00qf 5559 14 young young JJ cord-022526-j9kg00qf 5559 15 growing grow VBG cord-022526-j9kg00qf 5559 16 animals animal NNS cord-022526-j9kg00qf 5559 17 . . . cord-022526-j9kg00qf 5560 1 29 29 CD cord-022526-j9kg00qf 5561 1 However however RB cord-022526-j9kg00qf 5561 2 , , , cord-022526-j9kg00qf 5561 3 a a DT cord-022526-j9kg00qf 5561 4 recent recent JJ cord-022526-j9kg00qf 5561 5 study study NN cord-022526-j9kg00qf 5561 6 concluded conclude VBD cord-022526-j9kg00qf 5561 7 the the DT cord-022526-j9kg00qf 5561 8 drug drug NN cord-022526-j9kg00qf 5561 9 was be VBD cord-022526-j9kg00qf 5561 10 safe safe JJ cord-022526-j9kg00qf 5561 11 when when WRB cord-022526-j9kg00qf 5561 12 administered administer VBN cord-022526-j9kg00qf 5561 13 to to IN cord-022526-j9kg00qf 5561 14 adult adult NN cord-022526-j9kg00qf 5561 15 horses horse NNS cord-022526-j9kg00qf 5561 16 intravenously intravenously RB cord-022526-j9kg00qf 5561 17 at at IN cord-022526-j9kg00qf 5561 18 5 5 CD cord-022526-j9kg00qf 5561 19 mg mg NNP cord-022526-j9kg00qf 5561 20 / / SYM cord-022526-j9kg00qf 5561 21 kg kg NN cord-022526-j9kg00qf 5561 22 every every DT cord-022526-j9kg00qf 5561 23 24 24 CD cord-022526-j9kg00qf 5561 24 hours hour NNS cord-022526-j9kg00qf 5561 25 for for IN cord-022526-j9kg00qf 5561 26 3 3 CD cord-022526-j9kg00qf 5561 27 weeks week NNS cord-022526-j9kg00qf 5561 28 . . . cord-022526-j9kg00qf 5562 1 30 30 CD cord-022526-j9kg00qf 5563 1 One one CD cord-022526-j9kg00qf 5563 2 probably probably RB cord-022526-j9kg00qf 5563 3 should should MD cord-022526-j9kg00qf 5563 4 avoid avoid VB cord-022526-j9kg00qf 5563 5 using use VBG cord-022526-j9kg00qf 5563 6 the the DT cord-022526-j9kg00qf 5563 7 drug drug NN cord-022526-j9kg00qf 5563 8 in in IN cord-022526-j9kg00qf 5563 9 young young JJ cord-022526-j9kg00qf 5563 10 , , , cord-022526-j9kg00qf 5563 11 growing grow VBG cord-022526-j9kg00qf 5563 12 animals animal NNS cord-022526-j9kg00qf 5563 13 until until IN cord-022526-j9kg00qf 5563 14 the the DT cord-022526-j9kg00qf 5563 15 issue issue NN cord-022526-j9kg00qf 5563 16 of of IN cord-022526-j9kg00qf 5563 17 cartilage cartilage NN cord-022526-j9kg00qf 5563 18 damage damage NN cord-022526-j9kg00qf 5563 19 is be VBZ cord-022526-j9kg00qf 5563 20 resolved resolve VBN cord-022526-j9kg00qf 5563 21 . . . cord-022526-j9kg00qf 5564 1 Administration administration NN cord-022526-j9kg00qf 5564 2 of of IN cord-022526-j9kg00qf 5564 3 enrofloxacin enrofloxacin NNS cord-022526-j9kg00qf 5564 4 to to IN cord-022526-j9kg00qf 5564 5 horses horse NNS cord-022526-j9kg00qf 5564 6 constitutes constitute VBZ cord-022526-j9kg00qf 5564 7 off off IN cord-022526-j9kg00qf 5564 8 - - HYPH cord-022526-j9kg00qf 5564 9 label label NN cord-022526-j9kg00qf 5564 10 usage usage NN cord-022526-j9kg00qf 5564 11 . . . cord-022526-j9kg00qf 5565 1 One one PRP cord-022526-j9kg00qf 5565 2 should should MD cord-022526-j9kg00qf 5565 3 treat treat VB cord-022526-j9kg00qf 5565 4 horses horse NNS cord-022526-j9kg00qf 5565 5 with with IN cord-022526-j9kg00qf 5565 6 acute acute JJ cord-022526-j9kg00qf 5565 7 , , , cord-022526-j9kg00qf 5565 8 diffuse diffuse JJ cord-022526-j9kg00qf 5565 9 , , , cord-022526-j9kg00qf 5565 10 septic septic JJ cord-022526-j9kg00qf 5565 11 peritonitis peritonitis NN cord-022526-j9kg00qf 5565 12 with with IN cord-022526-j9kg00qf 5565 13 antibiotics antibiotic NNS cord-022526-j9kg00qf 5565 14 until until IN cord-022526-j9kg00qf 5565 15 the the DT cord-022526-j9kg00qf 5565 16 white white JJ cord-022526-j9kg00qf 5565 17 blood blood NN cord-022526-j9kg00qf 5565 18 cell cell NN cord-022526-j9kg00qf 5565 19 count count NN cord-022526-j9kg00qf 5565 20 , , , cord-022526-j9kg00qf 5565 21 plasma plasma NN cord-022526-j9kg00qf 5565 22 fibrinogen fibrinogen NN cord-022526-j9kg00qf 5565 23 , , , cord-022526-j9kg00qf 5565 24 and and CC cord-022526-j9kg00qf 5565 25 abdominal abdominal JJ cord-022526-j9kg00qf 5565 26 fluid fluid JJ cord-022526-j9kg00qf 5565 27 analysis analysis NN cord-022526-j9kg00qf 5565 28 are be VBP cord-022526-j9kg00qf 5565 29 normal normal JJ cord-022526-j9kg00qf 5565 30 . . . cord-022526-j9kg00qf 5566 1 In in IN cord-022526-j9kg00qf 5566 2 horses horse NNS cord-022526-j9kg00qf 5566 3 that that WDT cord-022526-j9kg00qf 5566 4 respond respond VBP cord-022526-j9kg00qf 5566 5 to to IN cord-022526-j9kg00qf 5566 6 therapy therapy NN cord-022526-j9kg00qf 5566 7 , , , cord-022526-j9kg00qf 5566 8 this this DT cord-022526-j9kg00qf 5566 9 process process NN cord-022526-j9kg00qf 5566 10 takes take VBZ cord-022526-j9kg00qf 5566 11 a a DT cord-022526-j9kg00qf 5566 12 variable variable JJ cord-022526-j9kg00qf 5566 13 amount amount NN cord-022526-j9kg00qf 5566 14 of of IN cord-022526-j9kg00qf 5566 15 time time NN cord-022526-j9kg00qf 5566 16 depending depend VBG cord-022526-j9kg00qf 5566 17 on on IN cord-022526-j9kg00qf 5566 18 the the DT cord-022526-j9kg00qf 5566 19 offending offend VBG cord-022526-j9kg00qf 5566 20 organisms organism NNS cord-022526-j9kg00qf 5566 21 and and CC cord-022526-j9kg00qf 5566 22 stage stage NN cord-022526-j9kg00qf 5566 23 of of IN cord-022526-j9kg00qf 5566 24 disease disease NN cord-022526-j9kg00qf 5566 25 at at IN cord-022526-j9kg00qf 5566 26 the the DT cord-022526-j9kg00qf 5566 27 time time NN cord-022526-j9kg00qf 5566 28 treatment treatment NN cord-022526-j9kg00qf 5566 29 is be VBZ cord-022526-j9kg00qf 5566 30 initiated initiate VBN cord-022526-j9kg00qf 5566 31 . . . cord-022526-j9kg00qf 5567 1 Horses horse NNS cord-022526-j9kg00qf 5567 2 with with IN cord-022526-j9kg00qf 5567 3 abdominal abdominal JJ cord-022526-j9kg00qf 5567 4 abscessation abscessation NN cord-022526-j9kg00qf 5567 5 resulting result VBG cord-022526-j9kg00qf 5567 6 from from IN cord-022526-j9kg00qf 5567 7 polymicrobial polymicrobial JJ cord-022526-j9kg00qf 5567 8 infection infection NN cord-022526-j9kg00qf 5567 9 may may MD cord-022526-j9kg00qf 5567 10 require require VB cord-022526-j9kg00qf 5567 11 many many JJ cord-022526-j9kg00qf 5567 12 months month NNS cord-022526-j9kg00qf 5567 13 of of IN cord-022526-j9kg00qf 5567 14 antibiotic antibiotic JJ cord-022526-j9kg00qf 5567 15 treatment treatment NN cord-022526-j9kg00qf 5567 16 . . . cord-022526-j9kg00qf 5568 1 Abdominal abdominal JJ cord-022526-j9kg00qf 5568 2 abscesses abscess NNS cord-022526-j9kg00qf 5568 3 caused cause VBN cord-022526-j9kg00qf 5568 4 by by IN cord-022526-j9kg00qf 5568 5 streptococci streptococcus NNS cord-022526-j9kg00qf 5568 6 and and CC cord-022526-j9kg00qf 5568 7 Corynebacterium Corynebacterium NNP cord-022526-j9kg00qf 5568 8 pseudotuberculosis pseudotuberculosis NN cord-022526-j9kg00qf 5568 9 also also RB cord-022526-j9kg00qf 5568 10 may may MD cord-022526-j9kg00qf 5568 11 require require VB cord-022526-j9kg00qf 5568 12 long long JJ cord-022526-j9kg00qf 5568 13 - - HYPH cord-022526-j9kg00qf 5568 14 term term NN cord-022526-j9kg00qf 5568 15 treatment treatment NN cord-022526-j9kg00qf 5568 16 ( ( -LRB- cord-022526-j9kg00qf 5568 17 weeks week NNS cord-022526-j9kg00qf 5568 18 to to IN cord-022526-j9kg00qf 5568 19 months month NNS cord-022526-j9kg00qf 5568 20 ) ) -RRB- cord-022526-j9kg00qf 5568 21 . . . cord-022526-j9kg00qf 5569 1 Long long JJ cord-022526-j9kg00qf 5569 2 - - HYPH cord-022526-j9kg00qf 5569 3 term term NN cord-022526-j9kg00qf 5569 4 antibiotic antibiotic JJ cord-022526-j9kg00qf 5569 5 treatment treatment NN cord-022526-j9kg00qf 5569 6 generally generally RB cord-022526-j9kg00qf 5569 7 necessitates necessitate VBZ cord-022526-j9kg00qf 5569 8 the the DT cord-022526-j9kg00qf 5569 9 use use NN cord-022526-j9kg00qf 5569 10 of of IN cord-022526-j9kg00qf 5569 11 oral oral JJ cord-022526-j9kg00qf 5569 12 antibiotics antibiotic NNS cord-022526-j9kg00qf 5569 13 , , , cord-022526-j9kg00qf 5569 14 and and CC cord-022526-j9kg00qf 5569 15 the the DT cord-022526-j9kg00qf 5569 16 options option NNS cord-022526-j9kg00qf 5569 17 are be VBP cord-022526-j9kg00qf 5569 18 limited limited JJ cord-022526-j9kg00qf 5569 19 . . . cord-022526-j9kg00qf 5570 1 Trimethoprim Trimethoprim NNP cord-022526-j9kg00qf 5570 2 - - HYPH cord-022526-j9kg00qf 5570 3 potentiated potentiate VBN cord-022526-j9kg00qf 5570 4 sulfonamides sulfonamide NNS cord-022526-j9kg00qf 5570 5 are be VBP cord-022526-j9kg00qf 5570 6 administered administer VBN cord-022526-j9kg00qf 5570 7 orally orally RB cord-022526-j9kg00qf 5570 8 and and CC cord-022526-j9kg00qf 5570 9 are be VBP cord-022526-j9kg00qf 5570 10 effective effective JJ cord-022526-j9kg00qf 5570 11 against against IN cord-022526-j9kg00qf 5570 12 a a DT cord-022526-j9kg00qf 5570 13 variety variety NN cord-022526-j9kg00qf 5570 14 of of IN cord-022526-j9kg00qf 5570 15 gram gram NN cord-022526-j9kg00qf 5570 16 - - HYPH cord-022526-j9kg00qf 5570 17 positive positive JJ cord-022526-j9kg00qf 5570 18 and and CC cord-022526-j9kg00qf 5570 19 gram gram JJ cord-022526-j9kg00qf 5570 20 - - HYPH cord-022526-j9kg00qf 5570 21 negative negative JJ cord-022526-j9kg00qf 5570 22 organisms organism NNS cord-022526-j9kg00qf 5570 23 , , , cord-022526-j9kg00qf 5570 24 although although IN cord-022526-j9kg00qf 5570 25 some some DT cord-022526-j9kg00qf 5570 26 streptococci streptococcus NNS cord-022526-j9kg00qf 5570 27 are be VBP cord-022526-j9kg00qf 5570 28 resistant resistant JJ cord-022526-j9kg00qf 5570 29 . . . cord-022526-j9kg00qf 5571 1 Metronidazole Metronidazole NNP cord-022526-j9kg00qf 5571 2 is be VBZ cord-022526-j9kg00qf 5571 3 an an DT cord-022526-j9kg00qf 5571 4 orally orally RB cord-022526-j9kg00qf 5571 5 administered administer VBN cord-022526-j9kg00qf 5571 6 drug drug NN cord-022526-j9kg00qf 5571 7 effective effective JJ cord-022526-j9kg00qf 5571 8 against against IN cord-022526-j9kg00qf 5571 9 anaerobic anaerobic JJ cord-022526-j9kg00qf 5571 10 bacteria bacteria NNS cord-022526-j9kg00qf 5571 11 , , , cord-022526-j9kg00qf 5571 12 as as IN cord-022526-j9kg00qf 5571 13 previously previously RB cord-022526-j9kg00qf 5571 14 discussed discuss VBN cord-022526-j9kg00qf 5571 15 . . . cord-022526-j9kg00qf 5572 1 Other other JJ cord-022526-j9kg00qf 5572 2 orally orally RB cord-022526-j9kg00qf 5572 3 administered administer VBD cord-022526-j9kg00qf 5572 4 antimicrobials antimicrobial NNS cord-022526-j9kg00qf 5572 5 one one PRP cord-022526-j9kg00qf 5572 6 may may MD cord-022526-j9kg00qf 5572 7 consider consider VB cord-022526-j9kg00qf 5572 8 for for IN cord-022526-j9kg00qf 5572 9 long long JJ cord-022526-j9kg00qf 5572 10 - - HYPH cord-022526-j9kg00qf 5572 11 term term NN cord-022526-j9kg00qf 5572 12 use use NN cord-022526-j9kg00qf 5572 13 include include VBP cord-022526-j9kg00qf 5572 14 doxycycline doxycycline NN cord-022526-j9kg00qf 5572 15 ( ( -LRB- cord-022526-j9kg00qf 5572 16 broad broad JJ cord-022526-j9kg00qf 5572 17 spectrum spectrum NN cord-022526-j9kg00qf 5572 18 ) ) -RRB- cord-022526-j9kg00qf 5572 19 , , . cord-022526-j9kg00qf 5573 1 erythromycin erythromycin NNP cord-022526-j9kg00qf 5573 2 ( ( -LRB- cord-022526-j9kg00qf 5573 3 gram gram NN cord-022526-j9kg00qf 5573 4 - - HYPH cord-022526-j9kg00qf 5573 5 positive positive JJ cord-022526-j9kg00qf 5573 6 spectrum spectrum NN cord-022526-j9kg00qf 5573 7 ) ) -RRB- cord-022526-j9kg00qf 5573 8 , , , cord-022526-j9kg00qf 5573 9 and and CC cord-022526-j9kg00qf 5573 10 enrofloxacin enrofloxacin NNS cord-022526-j9kg00qf 5573 11 ( ( -LRB- cord-022526-j9kg00qf 5573 12 mostly mostly RB cord-022526-j9kg00qf 5573 13 gram gram JJ cord-022526-j9kg00qf 5573 14 - - HYPH cord-022526-j9kg00qf 5573 15 negative negative JJ cord-022526-j9kg00qf 5573 16 spectrum spectrum NN cord-022526-j9kg00qf 5573 17 ) ) -RRB- cord-022526-j9kg00qf 5573 18 . . . cord-022526-j9kg00qf 5574 1 Importantly importantly RB cord-022526-j9kg00qf 5574 2 , , , cord-022526-j9kg00qf 5574 3 rifampin rifampin UH cord-022526-j9kg00qf 5574 4 , , , cord-022526-j9kg00qf 5574 5 when when WRB cord-022526-j9kg00qf 5574 6 used use VBN cord-022526-j9kg00qf 5574 7 with with IN cord-022526-j9kg00qf 5574 8 other other JJ cord-022526-j9kg00qf 5574 9 drugs drug NNS cord-022526-j9kg00qf 5574 10 , , , cord-022526-j9kg00qf 5574 11 can can MD cord-022526-j9kg00qf 5574 12 be be VB cord-022526-j9kg00qf 5574 13 effective effective JJ cord-022526-j9kg00qf 5574 14 in in IN cord-022526-j9kg00qf 5574 15 penetrating penetrate VBG cord-022526-j9kg00qf 5574 16 and and CC cord-022526-j9kg00qf 5574 17 resolving resolve VBG cord-022526-j9kg00qf 5574 18 abscesses abscess NNS cord-022526-j9kg00qf 5574 19 . . . cord-022526-j9kg00qf 5575 1 Combination combination NN cord-022526-j9kg00qf 5575 2 therapy therapy NN cord-022526-j9kg00qf 5575 3 with with IN cord-022526-j9kg00qf 5575 4 erythromycin erythromycin NN cord-022526-j9kg00qf 5575 5 and and CC cord-022526-j9kg00qf 5575 6 rifampin rifampin NN cord-022526-j9kg00qf 5575 7 is be VBZ cord-022526-j9kg00qf 5575 8 the the DT cord-022526-j9kg00qf 5575 9 standard standard JJ cord-022526-j9kg00qf 5575 10 treatment treatment NN cord-022526-j9kg00qf 5575 11 for for IN cord-022526-j9kg00qf 5575 12 Rhodococcus Rhodococcus NNP cord-022526-j9kg00qf 5575 13 equi equi NN cord-022526-j9kg00qf 5575 14 infection infection NN cord-022526-j9kg00qf 5575 15 in in IN cord-022526-j9kg00qf 5575 16 foals foal NNS cord-022526-j9kg00qf 5575 17 . . . cord-022526-j9kg00qf 5576 1 Peritonitis peritonitis NN cord-022526-j9kg00qf 5576 2 caused cause VBN cord-022526-j9kg00qf 5576 3 by by IN cord-022526-j9kg00qf 5576 4 Actinobacillus Actinobacillus NNP cord-022526-j9kg00qf 5576 5 equuli equuli NNP cord-022526-j9kg00qf 5576 6 usually usually RB cord-022526-j9kg00qf 5576 7 is be VBZ cord-022526-j9kg00qf 5576 8 manifested manifest VBN cord-022526-j9kg00qf 5576 9 as as IN cord-022526-j9kg00qf 5576 10 a a DT cord-022526-j9kg00qf 5576 11 diffuse diffuse NN cord-022526-j9kg00qf 5576 12 , , , cord-022526-j9kg00qf 5576 13 supporative supporative NNP cord-022526-j9kg00qf 5576 14 peritoneal peritoneal NN cord-022526-j9kg00qf 5576 15 exudate exudate NNP cord-022526-j9kg00qf 5576 16 . . . cord-022526-j9kg00qf 5577 1 6 6 CD cord-022526-j9kg00qf 5578 1 The the DT cord-022526-j9kg00qf 5578 2 same same JJ cord-022526-j9kg00qf 5578 3 is be VBZ cord-022526-j9kg00qf 5578 4 true true JJ cord-022526-j9kg00qf 5578 5 for for IN cord-022526-j9kg00qf 5578 6 some some DT cord-022526-j9kg00qf 5578 7 cases case NNS cord-022526-j9kg00qf 5578 8 involving involve VBG cord-022526-j9kg00qf 5578 9 streptococci streptococcus NNS cord-022526-j9kg00qf 5578 10 ( ( -LRB- cord-022526-j9kg00qf 5578 11 personal personal JJ cord-022526-j9kg00qf 5578 12 observation observation NN cord-022526-j9kg00qf 5578 13 ) ) -RRB- cord-022526-j9kg00qf 5578 14 . . . cord-022526-j9kg00qf 5579 1 These these DT cord-022526-j9kg00qf 5579 2 infections infection NNS cord-022526-j9kg00qf 5579 3 generally generally RB cord-022526-j9kg00qf 5579 4 respond respond VBP cord-022526-j9kg00qf 5579 5 well well RB cord-022526-j9kg00qf 5579 6 to to IN cord-022526-j9kg00qf 5579 7 combination combination NN cord-022526-j9kg00qf 5579 8 therapy therapy NN cord-022526-j9kg00qf 5579 9 with with IN cord-022526-j9kg00qf 5579 10 penicillin penicillin NN cord-022526-j9kg00qf 5579 11 and and CC cord-022526-j9kg00qf 5579 12 gentamicin gentamicin NN cord-022526-j9kg00qf 5579 13 . . . cord-022526-j9kg00qf 5580 1 If if IN cord-022526-j9kg00qf 5580 2 streptococci streptococcus NNS cord-022526-j9kg00qf 5580 3 are be VBP cord-022526-j9kg00qf 5580 4 involved involve VBN cord-022526-j9kg00qf 5580 5 as as IN cord-022526-j9kg00qf 5580 6 the the DT cord-022526-j9kg00qf 5580 7 sole sole JJ cord-022526-j9kg00qf 5580 8 pathogen pathogen NN cord-022526-j9kg00qf 5580 9 , , , cord-022526-j9kg00qf 5580 10 then then RB cord-022526-j9kg00qf 5580 11 penicillin penicillin NN cord-022526-j9kg00qf 5580 12 alone alone RB cord-022526-j9kg00qf 5580 13 should should MD cord-022526-j9kg00qf 5580 14 be be VB cord-022526-j9kg00qf 5580 15 effective effective JJ cord-022526-j9kg00qf 5580 16 . . . cord-022526-j9kg00qf 5581 1 Streptococci streptococcus NNS cord-022526-j9kg00qf 5581 2 potentially potentially RB cord-022526-j9kg00qf 5581 3 can can MD cord-022526-j9kg00qf 5581 4 be be VB cord-022526-j9kg00qf 5581 5 involved involve VBN cord-022526-j9kg00qf 5581 6 in in IN cord-022526-j9kg00qf 5581 7 mixed mixed JJ cord-022526-j9kg00qf 5581 8 , , , cord-022526-j9kg00qf 5581 9 synergistic synergistic JJ cord-022526-j9kg00qf 5581 10 peritoneal peritoneal JJ cord-022526-j9kg00qf 5581 11 infections infection NNS cord-022526-j9kg00qf 5581 12 in in IN cord-022526-j9kg00qf 5581 13 horses horse NNS cord-022526-j9kg00qf 5581 14 . . . cord-022526-j9kg00qf 5582 1 2 2 CD cord-022526-j9kg00qf 5582 2 Drainage drainage NN cord-022526-j9kg00qf 5582 3 or or CC cord-022526-j9kg00qf 5582 4 lavage lavage NN cord-022526-j9kg00qf 5582 5 of of IN cord-022526-j9kg00qf 5582 6 the the DT cord-022526-j9kg00qf 5582 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 5582 8 cavity cavity NN cord-022526-j9kg00qf 5582 9 may may MD cord-022526-j9kg00qf 5582 10 be be VB cord-022526-j9kg00qf 5582 11 of of IN cord-022526-j9kg00qf 5582 12 benefit benefit NN cord-022526-j9kg00qf 5582 13 in in IN cord-022526-j9kg00qf 5582 14 removing remove VBG cord-022526-j9kg00qf 5582 15 toxic toxic JJ cord-022526-j9kg00qf 5582 16 bacterial bacterial NN cord-022526-j9kg00qf 5582 17 by by IN cord-022526-j9kg00qf 5582 18 - - HYPH cord-022526-j9kg00qf 5582 19 products product NNS cord-022526-j9kg00qf 5582 20 and and CC cord-022526-j9kg00qf 5582 21 products product NNS cord-022526-j9kg00qf 5582 22 of of IN cord-022526-j9kg00qf 5582 23 inflammatory inflammatory JJ cord-022526-j9kg00qf 5582 24 cells cell NNS cord-022526-j9kg00qf 5582 25 . . . cord-022526-j9kg00qf 5583 1 31 31 CD cord-022526-j9kg00qf 5583 2 High high JJ cord-022526-j9kg00qf 5583 3 numbers number NNS cord-022526-j9kg00qf 5583 4 of of IN cord-022526-j9kg00qf 5583 5 inflammatory inflammatory JJ cord-022526-j9kg00qf 5583 6 cells cell NNS cord-022526-j9kg00qf 5583 7 and and CC cord-022526-j9kg00qf 5583 8 release release NN cord-022526-j9kg00qf 5583 9 of of IN cord-022526-j9kg00qf 5583 10 their -PRON- PRP$ cord-022526-j9kg00qf 5583 11 mediators mediator NNS cord-022526-j9kg00qf 5583 12 can can MD cord-022526-j9kg00qf 5583 13 persist persist VB cord-022526-j9kg00qf 5583 14 even even RB cord-022526-j9kg00qf 5583 15 after after IN cord-022526-j9kg00qf 5583 16 the the DT cord-022526-j9kg00qf 5583 17 primary primary JJ cord-022526-j9kg00qf 5583 18 stimulus stimulus NN cord-022526-j9kg00qf 5583 19 of of IN cord-022526-j9kg00qf 5583 20 the the DT cord-022526-j9kg00qf 5583 21 inflammatory inflammatory JJ cord-022526-j9kg00qf 5583 22 response response NN cord-022526-j9kg00qf 5583 23 has have VBZ cord-022526-j9kg00qf 5583 24 resolved resolve VBN cord-022526-j9kg00qf 5583 25 . . . cord-022526-j9kg00qf 5584 1 Infusing infuse VBG cord-022526-j9kg00qf 5584 2 large large JJ cord-022526-j9kg00qf 5584 3 volumes volume NNS cord-022526-j9kg00qf 5584 4 of of IN cord-022526-j9kg00qf 5584 5 isotonic isotonic JJ cord-022526-j9kg00qf 5584 6 , , , cord-022526-j9kg00qf 5584 7 warmed warm VBD cord-022526-j9kg00qf 5584 8 fluid fluid NN cord-022526-j9kg00qf 5584 9 into into IN cord-022526-j9kg00qf 5584 10 the the DT cord-022526-j9kg00qf 5584 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 5584 12 cavity cavity NN cord-022526-j9kg00qf 5584 13 also also RB cord-022526-j9kg00qf 5584 14 dilutes dilute VBZ cord-022526-j9kg00qf 5584 15 the the DT cord-022526-j9kg00qf 5584 16 inflammatory inflammatory JJ cord-022526-j9kg00qf 5584 17 mediators mediator NNS cord-022526-j9kg00qf 5584 18 , , , cord-022526-j9kg00qf 5584 19 possibly possibly RB cord-022526-j9kg00qf 5584 20 reducing reduce VBG cord-022526-j9kg00qf 5584 21 their -PRON- PRP$ cord-022526-j9kg00qf 5584 22 deleterious deleterious JJ cord-022526-j9kg00qf 5584 23 effects effect NNS cord-022526-j9kg00qf 5584 24 . . . cord-022526-j9kg00qf 5585 1 When when WRB cord-022526-j9kg00qf 5585 2 successful successful JJ cord-022526-j9kg00qf 5585 3 , , , cord-022526-j9kg00qf 5585 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5585 5 lavage lavage NN cord-022526-j9kg00qf 5585 6 decreases decrease VBZ cord-022526-j9kg00qf 5585 7 the the DT cord-022526-j9kg00qf 5585 8 peritoneal peritoneal JJ cord-022526-j9kg00qf 5585 9 fluid fluid NN cord-022526-j9kg00qf 5585 10 WBC WBC NNP cord-022526-j9kg00qf 5585 11 count count NN cord-022526-j9kg00qf 5585 12 and and CC cord-022526-j9kg00qf 5585 13 total total JJ cord-022526-j9kg00qf 5585 14 protein protein NN cord-022526-j9kg00qf 5585 15 , , , cord-022526-j9kg00qf 5585 16 potentially potentially RB cord-022526-j9kg00qf 5585 17 reflecting reflect VBG cord-022526-j9kg00qf 5585 18 a a DT cord-022526-j9kg00qf 5585 19 decrease decrease NN cord-022526-j9kg00qf 5585 20 in in IN cord-022526-j9kg00qf 5585 21 diffuse diffuse JJ cord-022526-j9kg00qf 5585 22 inflammation inflammation NN cord-022526-j9kg00qf 5585 23 . . . cord-022526-j9kg00qf 5586 1 The the DT cord-022526-j9kg00qf 5586 2 benefits benefit NNS cord-022526-j9kg00qf 5586 3 of of IN cord-022526-j9kg00qf 5586 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5586 5 lavage lavage NN cord-022526-j9kg00qf 5586 6 are be VBP cord-022526-j9kg00qf 5586 7 controversial controversial JJ cord-022526-j9kg00qf 5586 8 , , , cord-022526-j9kg00qf 5586 9 and and CC cord-022526-j9kg00qf 5586 10 a a DT cord-022526-j9kg00qf 5586 11 positive positive JJ cord-022526-j9kg00qf 5586 12 effect effect NN cord-022526-j9kg00qf 5586 13 may may MD cord-022526-j9kg00qf 5586 14 be be VB cord-022526-j9kg00qf 5586 15 more more RBR cord-022526-j9kg00qf 5586 16 likely likely JJ cord-022526-j9kg00qf 5586 17 during during IN cord-022526-j9kg00qf 5586 18 the the DT cord-022526-j9kg00qf 5586 19 acute acute JJ cord-022526-j9kg00qf 5586 20 , , , cord-022526-j9kg00qf 5586 21 diffuse diffuse JJ cord-022526-j9kg00qf 5586 22 stage stage NN cord-022526-j9kg00qf 5586 23 of of IN cord-022526-j9kg00qf 5586 24 disease disease NN cord-022526-j9kg00qf 5586 25 . . . cord-022526-j9kg00qf 5587 1 2 2 CD cord-022526-j9kg00qf 5587 2 , , , cord-022526-j9kg00qf 5587 3 4 4 CD cord-022526-j9kg00qf 5588 1 Some some DT cord-022526-j9kg00qf 5588 2 studies study NNS cord-022526-j9kg00qf 5588 3 suggest suggest VBP cord-022526-j9kg00qf 5588 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5588 5 lavage lavage NN cord-022526-j9kg00qf 5588 6 , , , cord-022526-j9kg00qf 5588 7 along along IN cord-022526-j9kg00qf 5588 8 with with IN cord-022526-j9kg00qf 5588 9 heparin heparin NN cord-022526-j9kg00qf 5588 10 therapy therapy NN cord-022526-j9kg00qf 5588 11 , , , cord-022526-j9kg00qf 5588 12 may may MD cord-022526-j9kg00qf 5588 13 reduce reduce VB cord-022526-j9kg00qf 5588 14 the the DT cord-022526-j9kg00qf 5588 15 incidence incidence NN cord-022526-j9kg00qf 5588 16 of of IN cord-022526-j9kg00qf 5588 17 adhesions adhesion NNS cord-022526-j9kg00qf 5588 18 . . . cord-022526-j9kg00qf 5589 1 2 2 LS cord-022526-j9kg00qf 5590 1 One one PRP cord-022526-j9kg00qf 5590 2 should should MD cord-022526-j9kg00qf 5590 3 perform perform VB cord-022526-j9kg00qf 5590 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5590 5 drainage drainage NN cord-022526-j9kg00qf 5590 6 and and CC cord-022526-j9kg00qf 5590 7 lavage lavage NN cord-022526-j9kg00qf 5590 8 using use VBG cord-022526-j9kg00qf 5590 9 a a DT cord-022526-j9kg00qf 5590 10 drain drain NN cord-022526-j9kg00qf 5590 11 of of IN cord-022526-j9kg00qf 5590 12 no no DT cord-022526-j9kg00qf 5590 13 less less JJR cord-022526-j9kg00qf 5590 14 than than IN cord-022526-j9kg00qf 5590 15 24F 24F NNP cord-022526-j9kg00qf 5590 16 diameter diameter NN cord-022526-j9kg00qf 5590 17 . . . cord-022526-j9kg00qf 5591 1 Foley Foley NNP cord-022526-j9kg00qf 5591 2 - - HYPH cord-022526-j9kg00qf 5591 3 type type NN cord-022526-j9kg00qf 5591 4 catheters catheter NNS cord-022526-j9kg00qf 5591 5 can can MD cord-022526-j9kg00qf 5591 6 be be VB cord-022526-j9kg00qf 5591 7 used use VBN cord-022526-j9kg00qf 5591 8 , , , cord-022526-j9kg00qf 5591 9 but but CC cord-022526-j9kg00qf 5591 10 " " `` cord-022526-j9kg00qf 5591 11 mushroom mushroom NN cord-022526-j9kg00qf 5591 12 " " '' cord-022526-j9kg00qf 5591 13 drains drain NNS cord-022526-j9kg00qf 5591 14 provide provide VB cord-022526-j9kg00qf 5591 15 a a DT cord-022526-j9kg00qf 5591 16 larger large JJR cord-022526-j9kg00qf 5591 17 area area NN cord-022526-j9kg00qf 5591 18 for for IN cord-022526-j9kg00qf 5591 19 fluid fluid NN cord-022526-j9kg00qf 5591 20 to to TO cord-022526-j9kg00qf 5591 21 enter enter VB cord-022526-j9kg00qf 5591 22 the the DT cord-022526-j9kg00qf 5591 23 drain drain NN cord-022526-j9kg00qf 5591 24 . . . cord-022526-j9kg00qf 5592 1 Two two CD cord-022526-j9kg00qf 5592 2 approaches approach NNS cord-022526-j9kg00qf 5592 3 to to IN cord-022526-j9kg00qf 5592 4 peritoneal peritoneal JJ cord-022526-j9kg00qf 5592 5 lavage lavage NN cord-022526-j9kg00qf 5592 6 are be VBP cord-022526-j9kg00qf 5592 7 ( ( -LRB- cord-022526-j9kg00qf 5592 8 1 1 LS cord-022526-j9kg00qf 5592 9 ) ) -RRB- cord-022526-j9kg00qf 5592 10 retrograde retrograde JJ cord-022526-j9kg00qf 5592 11 irrigation irrigation NN cord-022526-j9kg00qf 5592 12 through through IN cord-022526-j9kg00qf 5592 13 a a DT cord-022526-j9kg00qf 5592 14 ventrally ventrally RB cord-022526-j9kg00qf 5592 15 placed place VBN cord-022526-j9kg00qf 5592 16 ingress ingress NN cord-022526-j9kg00qf 5592 17 - - HYPH cord-022526-j9kg00qf 5592 18 egress egress NN cord-022526-j9kg00qf 5592 19 drain drain NN cord-022526-j9kg00qf 5592 20 and and CC cord-022526-j9kg00qf 5592 21 ( ( -LRB- cord-022526-j9kg00qf 5592 22 2 2 LS cord-022526-j9kg00qf 5592 23 ) ) -RRB- cord-022526-j9kg00qf 5592 24 placement placement NN cord-022526-j9kg00qf 5592 25 of of IN cord-022526-j9kg00qf 5592 26 ingress ingress NN cord-022526-j9kg00qf 5592 27 catheter(s catheter(s NNP cord-022526-j9kg00qf 5592 28 ) ) -RRB- cord-022526-j9kg00qf 5592 29 in in IN cord-022526-j9kg00qf 5592 30 the the DT cord-022526-j9kg00qf 5592 31 paralumbar paralumbar NN cord-022526-j9kg00qf 5592 32 fossa(e fossa(e NNP cord-022526-j9kg00qf 5592 33 ) ) -RRB- cord-022526-j9kg00qf 5592 34 for for IN cord-022526-j9kg00qf 5592 35 infusion infusion NN cord-022526-j9kg00qf 5592 36 of of IN cord-022526-j9kg00qf 5592 37 fluids fluid NNS cord-022526-j9kg00qf 5592 38 , , , cord-022526-j9kg00qf 5592 39 with with IN cord-022526-j9kg00qf 5592 40 a a DT cord-022526-j9kg00qf 5592 41 drain drain NN cord-022526-j9kg00qf 5592 42 placed place VBN cord-022526-j9kg00qf 5592 43 ventrally ventrally RB cord-022526-j9kg00qf 5592 44 for for IN cord-022526-j9kg00qf 5592 45 removal removal NN cord-022526-j9kg00qf 5592 46 of of IN cord-022526-j9kg00qf 5592 47 infused infuse VBN cord-022526-j9kg00qf 5592 48 fluid fluid NN cord-022526-j9kg00qf 5592 49 . . . cord-022526-j9kg00qf 5593 1 One one PRP cord-022526-j9kg00qf 5593 2 must must MD cord-022526-j9kg00qf 5593 3 recognize recognize VB cord-022526-j9kg00qf 5593 4 that that IN cord-022526-j9kg00qf 5593 5 thorough thorough JJ cord-022526-j9kg00qf 5593 6 peritoneal peritoneal NN cord-022526-j9kg00qf 5593 7 lavage lavage NN cord-022526-j9kg00qf 5593 8 can can MD cord-022526-j9kg00qf 5593 9 be be VB cord-022526-j9kg00qf 5593 10 achieved achieve VBN cord-022526-j9kg00qf 5593 11 only only RB cord-022526-j9kg00qf 5593 12 via via IN cord-022526-j9kg00qf 5593 13 ventral ventral JJ cord-022526-j9kg00qf 5593 14 midline midline JJ cord-022526-j9kg00qf 5593 15 laparotomy laparotomy NN cord-022526-j9kg00qf 5593 16 . . . cord-022526-j9kg00qf 5594 1 Complications complication NNS cord-022526-j9kg00qf 5594 2 associated associate VBN cord-022526-j9kg00qf 5594 3 with with IN cord-022526-j9kg00qf 5594 4 the the DT cord-022526-j9kg00qf 5594 5 use use NN cord-022526-j9kg00qf 5594 6 of of IN cord-022526-j9kg00qf 5594 7 abdominal abdominal JJ cord-022526-j9kg00qf 5594 8 drains drain NNS cord-022526-j9kg00qf 5594 9 or or CC cord-022526-j9kg00qf 5594 10 repeated repeat VBN cord-022526-j9kg00qf 5594 11 peritoneal peritoneal JJ cord-022526-j9kg00qf 5594 12 penetration penetration NN cord-022526-j9kg00qf 5594 13 to to TO cord-022526-j9kg00qf 5594 14 drain drain VB cord-022526-j9kg00qf 5594 15 fluid fluid NN cord-022526-j9kg00qf 5594 16 include include VBP cord-022526-j9kg00qf 5594 17 retrograde retrograde JJ cord-022526-j9kg00qf 5594 18 infection infection NN cord-022526-j9kg00qf 5594 19 , , , cord-022526-j9kg00qf 5594 20 local local JJ cord-022526-j9kg00qf 5594 21 irritation irritation NN cord-022526-j9kg00qf 5594 22 , , , cord-022526-j9kg00qf 5594 23 pneumoperitoneum pneumoperitoneum NNP cord-022526-j9kg00qf 5594 24 , , , cord-022526-j9kg00qf 5594 25 and and CC cord-022526-j9kg00qf 5594 26 subcutaneous subcutaneous JJ cord-022526-j9kg00qf 5594 27 seepage seepage NN cord-022526-j9kg00qf 5594 28 around around IN cord-022526-j9kg00qf 5594 29 the the DT cord-022526-j9kg00qf 5594 30 drain drain NN cord-022526-j9kg00qf 5594 31 and and CC cord-022526-j9kg00qf 5594 32 resultant resultant JJ cord-022526-j9kg00qf 5594 33 cellulitis cellulitis NN cord-022526-j9kg00qf 5594 34 . . . cord-022526-j9kg00qf 5595 1 If if IN cord-022526-j9kg00qf 5595 2 the the DT cord-022526-j9kg00qf 5595 3 patient patient NN cord-022526-j9kg00qf 5595 4 is be VBZ cord-022526-j9kg00qf 5595 5 hypovolemic hypovolemic JJ cord-022526-j9kg00qf 5595 6 or or CC cord-022526-j9kg00qf 5595 7 hypoproteinemic hypoproteinemic JJ cord-022526-j9kg00qf 5595 8 , , , cord-022526-j9kg00qf 5595 9 one one PRP cord-022526-j9kg00qf 5595 10 should should MD cord-022526-j9kg00qf 5595 11 consider consider VB cord-022526-j9kg00qf 5595 12 volume volume NN cord-022526-j9kg00qf 5595 13 replacement replacement NN cord-022526-j9kg00qf 5595 14 and and CC cord-022526-j9kg00qf 5595 15 administration administration NN cord-022526-j9kg00qf 5595 16 of of IN cord-022526-j9kg00qf 5595 17 plasma plasma NN cord-022526-j9kg00qf 5595 18 before before IN cord-022526-j9kg00qf 5595 19 removing remove VBG cord-022526-j9kg00qf 5595 20 large large JJ cord-022526-j9kg00qf 5595 21 quantities quantity NNS cord-022526-j9kg00qf 5595 22 of of IN cord-022526-j9kg00qf 5595 23 fluid fluid NN cord-022526-j9kg00qf 5595 24 from from IN cord-022526-j9kg00qf 5595 25 the the DT cord-022526-j9kg00qf 5595 26 abdomen abdomen NN cord-022526-j9kg00qf 5595 27 . . . cord-022526-j9kg00qf 5596 1 In in IN cord-022526-j9kg00qf 5596 2 horses horse NNS cord-022526-j9kg00qf 5596 3 with with IN cord-022526-j9kg00qf 5596 4 suspected suspect VBN cord-022526-j9kg00qf 5596 5 parasite parasite NN cord-022526-j9kg00qf 5596 6 involvement involvement NN cord-022526-j9kg00qf 5596 7 , , , cord-022526-j9kg00qf 5596 8 such such JJ cord-022526-j9kg00qf 5596 9 as as IN cord-022526-j9kg00qf 5596 10 verminous verminous JJ cord-022526-j9kg00qf 5596 11 arteritis arteritis NN cord-022526-j9kg00qf 5596 12 , , , cord-022526-j9kg00qf 5596 13 one one PRP cord-022526-j9kg00qf 5596 14 should should MD cord-022526-j9kg00qf 5596 15 give give VB cord-022526-j9kg00qf 5596 16 larvicidal larvicidal JJ cord-022526-j9kg00qf 5596 17 doses dose NNS cord-022526-j9kg00qf 5596 18 of of IN cord-022526-j9kg00qf 5596 19 an an DT cord-022526-j9kg00qf 5596 20 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 5596 21 once once IN cord-022526-j9kg00qf 5596 22 the the DT cord-022526-j9kg00qf 5596 23 condition condition NN cord-022526-j9kg00qf 5596 24 of of IN cord-022526-j9kg00qf 5596 25 the the DT cord-022526-j9kg00qf 5596 26 horse horse NN cord-022526-j9kg00qf 5596 27 is be VBZ cord-022526-j9kg00qf 5596 28 stabilized stabilize VBN cord-022526-j9kg00qf 5596 29 . . . cord-022526-j9kg00qf 5597 1 Ivermectin Ivermectin NNP cord-022526-j9kg00qf 5597 2 , , , cord-022526-j9kg00qf 5597 3 fenbendazole fenbendazole NN cord-022526-j9kg00qf 5597 4 , , , cord-022526-j9kg00qf 5597 5 and and CC cord-022526-j9kg00qf 5597 6 thiabendazole thiabendazole NNP cord-022526-j9kg00qf 5597 7 have have VBP cord-022526-j9kg00qf 5597 8 been be VBN cord-022526-j9kg00qf 5597 9 recommended recommend VBN cord-022526-j9kg00qf 5597 10 as as IN cord-022526-j9kg00qf 5597 11 larvacidal larvacidal NNP cord-022526-j9kg00qf 5597 12 therapies therapy NNS cord-022526-j9kg00qf 5597 13 . . . cord-022526-j9kg00qf 5598 1 Visualization visualization NN cord-022526-j9kg00qf 5598 2 of of IN cord-022526-j9kg00qf 5598 3 auscultation auscultation NN cord-022526-j9kg00qf 5598 4 sounds sound NNS cord-022526-j9kg00qf 5598 5 of of IN cord-022526-j9kg00qf 5598 6 the the DT cord-022526-j9kg00qf 5598 7 large large JJ cord-022526-j9kg00qf 5598 8 intestine intestine NN cord-022526-j9kg00qf 5598 9 Small small JJ cord-022526-j9kg00qf 5598 10 intestinal intestinal JJ cord-022526-j9kg00qf 5598 11 betagalactosidase betagalactosidase NN cord-022526-j9kg00qf 5598 12 activity activity NN cord-022526-j9kg00qf 5598 13 in in IN cord-022526-j9kg00qf 5598 14 the the DT cord-022526-j9kg00qf 5598 15 horse horse NN cord-022526-j9kg00qf 5598 16 Rectal rectal JJ cord-022526-j9kg00qf 5598 17 biopsy biopsy NN cord-022526-j9kg00qf 5598 18 diagnosis diagnosis NN cord-022526-j9kg00qf 5598 19 in in IN cord-022526-j9kg00qf 5598 20 horses horse NNS cord-022526-j9kg00qf 5598 21 with with IN cord-022526-j9kg00qf 5598 22 clinical clinical JJ cord-022526-j9kg00qf 5598 23 signs sign NNS cord-022526-j9kg00qf 5598 24 of of IN cord-022526-j9kg00qf 5598 25 intestinal intestinal JJ cord-022526-j9kg00qf 5598 26 disorders disorder NNS cord-022526-j9kg00qf 5598 27 : : : cord-022526-j9kg00qf 5598 28 a a DT cord-022526-j9kg00qf 5598 29 retrospective retrospective JJ cord-022526-j9kg00qf 5598 30 study study NN cord-022526-j9kg00qf 5598 31 of of IN cord-022526-j9kg00qf 5598 32 116 116 CD cord-022526-j9kg00qf 5598 33 cases case NNS cord-022526-j9kg00qf 5598 34 Equine equine JJ cord-022526-j9kg00qf 5598 35 lymphocyticplasmacytic lymphocyticplasmacytic JJ cord-022526-j9kg00qf 5598 36 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5598 37 : : : cord-022526-j9kg00qf 5598 38 a a DT cord-022526-j9kg00qf 5598 39 retrospective retrospective JJ cord-022526-j9kg00qf 5598 40 study study NN cord-022526-j9kg00qf 5598 41 of of IN cord-022526-j9kg00qf 5598 42 14 14 CD cord-022526-j9kg00qf 5598 43 cases case NNS cord-022526-j9kg00qf 5598 44 Eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5598 45 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5598 46 and and CC cord-022526-j9kg00qf 5598 47 dermatitis dermatitis NN cord-022526-j9kg00qf 5598 48 in in IN cord-022526-j9kg00qf 5598 49 two two CD cord-022526-j9kg00qf 5598 50 horses horse NNS cord-022526-j9kg00qf 5599 1 Breath breath NN cord-022526-j9kg00qf 5599 2 hydrogen hydrogen NN cord-022526-j9kg00qf 5599 3 measurements measurement NNS cord-022526-j9kg00qf 5599 4 in in IN cord-022526-j9kg00qf 5599 5 ponies pony NNS cord-022526-j9kg00qf 5599 6 : : : cord-022526-j9kg00qf 5599 7 a a DT cord-022526-j9kg00qf 5599 8 preliminary preliminary JJ cord-022526-j9kg00qf 5599 9 study study NN cord-022526-j9kg00qf 5600 1 The the DT cord-022526-j9kg00qf 5600 2 oral oral JJ cord-022526-j9kg00qf 5600 3 glucose glucose NN cord-022526-j9kg00qf 5600 4 tolerance tolerance NN cord-022526-j9kg00qf 5600 5 test test NN cord-022526-j9kg00qf 5600 6 in in IN cord-022526-j9kg00qf 5600 7 the the DT cord-022526-j9kg00qf 5600 8 horse horse NN cord-022526-j9kg00qf 5600 9 Small small JJ cord-022526-j9kg00qf 5600 10 intestinal intestinal JJ cord-022526-j9kg00qf 5600 11 malabsorption malabsorption NN cord-022526-j9kg00qf 5600 12 in in IN cord-022526-j9kg00qf 5600 13 the the DT cord-022526-j9kg00qf 5600 14 horse horse NN cord-022526-j9kg00qf 5600 15 : : : cord-022526-j9kg00qf 5600 16 an an DT cord-022526-j9kg00qf 5600 17 assessment assessment NN cord-022526-j9kg00qf 5600 18 of of IN cord-022526-j9kg00qf 5600 19 the the DT cord-022526-j9kg00qf 5600 20 specificity specificity NN cord-022526-j9kg00qf 5600 21 of of IN cord-022526-j9kg00qf 5600 22 the the DT cord-022526-j9kg00qf 5600 23 oral oral JJ cord-022526-j9kg00qf 5600 24 glucose glucose NN cord-022526-j9kg00qf 5600 25 tolerance tolerance NN cord-022526-j9kg00qf 5600 26 test test VBP cord-022526-j9kg00qf 5600 27 Transient transient JJ cord-022526-j9kg00qf 5600 28 glucose glucose NN cord-022526-j9kg00qf 5600 29 malabsorption malabsorption NN cord-022526-j9kg00qf 5600 30 in in IN cord-022526-j9kg00qf 5600 31 two two CD cord-022526-j9kg00qf 5600 32 horses horse NNS cord-022526-j9kg00qf 5600 33 : : : cord-022526-j9kg00qf 5600 34 fact fact NN cord-022526-j9kg00qf 5600 35 or or CC cord-022526-j9kg00qf 5600 36 artifact artifact NN cord-022526-j9kg00qf 5600 37 ? ? . cord-022526-j9kg00qf 5601 1 Chronic chronic JJ cord-022526-j9kg00qf 5601 2 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5601 3 in in IN cord-022526-j9kg00qf 5601 4 adult adult NN cord-022526-j9kg00qf 5601 5 horses horse NNS cord-022526-j9kg00qf 5601 6 : : : cord-022526-j9kg00qf 5601 7 a a DT cord-022526-j9kg00qf 5601 8 review review NN cord-022526-j9kg00qf 5601 9 of of IN cord-022526-j9kg00qf 5601 10 51 51 CD cord-022526-j9kg00qf 5601 11 referred refer VBN cord-022526-j9kg00qf 5601 12 cases case NNS cord-022526-j9kg00qf 5601 13 Effect effect NN cord-022526-j9kg00qf 5601 14 of of IN cord-022526-j9kg00qf 5601 15 food food NN cord-022526-j9kg00qf 5601 16 deprivation deprivation NN cord-022526-j9kg00qf 5601 17 on on IN cord-022526-j9kg00qf 5601 18 D d NN cord-022526-j9kg00qf 5601 19 - - HYPH cord-022526-j9kg00qf 5601 20 xylose xylose NN cord-022526-j9kg00qf 5601 21 absorption absorption NN cord-022526-j9kg00qf 5601 22 test test NN cord-022526-j9kg00qf 5601 23 results result NNS cord-022526-j9kg00qf 5601 24 in in IN cord-022526-j9kg00qf 5601 25 mares mare NNS cord-022526-j9kg00qf 5601 26 Malabsorption malabsorption NN cord-022526-j9kg00qf 5601 27 syndromes syndrome NNS cord-022526-j9kg00qf 5601 28 in in IN cord-022526-j9kg00qf 5601 29 the the DT cord-022526-j9kg00qf 5601 30 horse horse NN cord-022526-j9kg00qf 5602 1 The the DT cord-022526-j9kg00qf 5602 2 diagnostic diagnostic JJ cord-022526-j9kg00qf 5602 3 value value NN cord-022526-j9kg00qf 5602 4 of of IN cord-022526-j9kg00qf 5602 5 the the DT cord-022526-j9kg00qf 5602 6 D d JJ cord-022526-j9kg00qf 5602 7 - - HYPH cord-022526-j9kg00qf 5602 8 xylose xylose NN cord-022526-j9kg00qf 5602 9 absorption absorption NN cord-022526-j9kg00qf 5602 10 test test NN cord-022526-j9kg00qf 5602 11 in in IN cord-022526-j9kg00qf 5602 12 horses horse NNS cord-022526-j9kg00qf 5602 13 with with IN cord-022526-j9kg00qf 5602 14 unexplained unexplained JJ cord-022526-j9kg00qf 5602 15 chronic chronic JJ cord-022526-j9kg00qf 5602 16 weight weight NN cord-022526-j9kg00qf 5602 17 loss loss NN cord-022526-j9kg00qf 5602 18 Small small JJ cord-022526-j9kg00qf 5602 19 intestinal intestinal JJ cord-022526-j9kg00qf 5602 20 malabsorption malabsorption NN cord-022526-j9kg00qf 5602 21 in in IN cord-022526-j9kg00qf 5602 22 horses horse NNS cord-022526-j9kg00qf 5603 1 Effects effect NNS cord-022526-j9kg00qf 5603 2 of of IN cord-022526-j9kg00qf 5603 3 extensive extensive JJ cord-022526-j9kg00qf 5603 4 small small JJ cord-022526-j9kg00qf 5603 5 intestinal intestinal JJ cord-022526-j9kg00qf 5603 6 resection resection NN cord-022526-j9kg00qf 5603 7 in in IN cord-022526-j9kg00qf 5603 8 the the DT cord-022526-j9kg00qf 5603 9 pony pony NN cord-022526-j9kg00qf 5603 10 Effects effect NNS cord-022526-j9kg00qf 5603 11 of of IN cord-022526-j9kg00qf 5603 12 extensive extensive JJ cord-022526-j9kg00qf 5603 13 resection resection NN cord-022526-j9kg00qf 5603 14 of of IN cord-022526-j9kg00qf 5603 15 the the DT cord-022526-j9kg00qf 5603 16 small small JJ cord-022526-j9kg00qf 5603 17 intestine intestine NN cord-022526-j9kg00qf 5603 18 in in IN cord-022526-j9kg00qf 5603 19 the the DT cord-022526-j9kg00qf 5603 20 pony pony NN cord-022526-j9kg00qf 5603 21 Clinical clinical JJ cord-022526-j9kg00qf 5603 22 remission remission NN cord-022526-j9kg00qf 5603 23 of of IN cord-022526-j9kg00qf 5603 24 granulomatous granulomatous JJ cord-022526-j9kg00qf 5603 25 enteritis enteritis NN cord-022526-j9kg00qf 5603 26 in in IN cord-022526-j9kg00qf 5603 27 a a DT cord-022526-j9kg00qf 5603 28 standardbred standardbred JJ cord-022526-j9kg00qf 5603 29 gelding gelding NN cord-022526-j9kg00qf 5603 30 following follow VBG cord-022526-j9kg00qf 5603 31 long long JJ cord-022526-j9kg00qf 5603 32 term term NN cord-022526-j9kg00qf 5603 33 dexamethasone dexamethasone NNP cord-022526-j9kg00qf 5603 34 administration administration NN cord-022526-j9kg00qf 5603 35 Clinical clinical JJ cord-022526-j9kg00qf 5603 36 and and CC cord-022526-j9kg00qf 5603 37 pathophysiological pathophysiological JJ cord-022526-j9kg00qf 5603 38 features feature NNS cord-022526-j9kg00qf 5603 39 of of IN cord-022526-j9kg00qf 5603 40 granulomatous granulomatous JJ cord-022526-j9kg00qf 5603 41 enteritis enteritis NN cord-022526-j9kg00qf 5603 42 and and CC cord-022526-j9kg00qf 5603 43 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5603 44 granulomatosis granulomatosis NN cord-022526-j9kg00qf 5603 45 in in IN cord-022526-j9kg00qf 5603 46 the the DT cord-022526-j9kg00qf 5603 47 horse horse NN cord-022526-j9kg00qf 5603 48 Inflammatory inflammatory JJ cord-022526-j9kg00qf 5603 49 bowel bowel NN cord-022526-j9kg00qf 5603 50 disease disease NN cord-022526-j9kg00qf 5603 51 in in IN cord-022526-j9kg00qf 5603 52 horses horse NNS cord-022526-j9kg00qf 5603 53 : : : cord-022526-j9kg00qf 5603 54 11 11 CD cord-022526-j9kg00qf 5603 55 cases case NNS cord-022526-j9kg00qf 5603 56 Segmental segmental VB cord-022526-j9kg00qf 5603 57 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5603 58 colitis colitis NN cord-022526-j9kg00qf 5603 59 : : : cord-022526-j9kg00qf 5603 60 a a DT cord-022526-j9kg00qf 5603 61 review review NN cord-022526-j9kg00qf 5603 62 of of IN cord-022526-j9kg00qf 5603 63 22 22 CD cord-022526-j9kg00qf 5603 64 cases case NNS cord-022526-j9kg00qf 5603 65 Chronic chronic VBP cord-022526-j9kg00qf 5603 66 idiopathic idiopathic JJ cord-022526-j9kg00qf 5603 67 inflammatory inflammatory JJ cord-022526-j9kg00qf 5603 68 bowel bowel NN cord-022526-j9kg00qf 5603 69 diseases disease NNS cord-022526-j9kg00qf 5603 70 of of IN cord-022526-j9kg00qf 5603 71 the the DT cord-022526-j9kg00qf 5603 72 horse horse NN cord-022526-j9kg00qf 5603 73 SECTION section NN cord-022526-j9kg00qf 5603 74 13.4 13.4 CD cord-022526-j9kg00qf 5603 75 Malabsorption malabsorption NN cord-022526-j9kg00qf 5603 76 Syndromes Syndromes NNPS cord-022526-j9kg00qf 5603 77 and and CC cord-022526-j9kg00qf 5603 78 Maldigestion Maldigestion NNP cord-022526-j9kg00qf 5603 79 : : : cord-022526-j9kg00qf 5603 80 Pathophysiology Pathophysiology NNP cord-022526-j9kg00qf 5603 81 , , , cord-022526-j9kg00qf 5603 82 Assessment Assessment NNP cord-022526-j9kg00qf 5603 83 , , , cord-022526-j9kg00qf 5603 84 Management Management NNP cord-022526-j9kg00qf 5603 85 , , , cord-022526-j9kg00qf 5603 86 and and CC cord-022526-j9kg00qf 5603 87 Outcome outcome NN cord-022526-j9kg00qf 5603 88 REFERENCES reference NNS cord-022526-j9kg00qf 5603 89 of of IN cord-022526-j9kg00qf 5603 90 Critical Critical NNP cord-022526-j9kg00qf 5603 91 Care Care NNP cord-022526-j9kg00qf 5603 92 Medicine Medicine NNP cord-022526-j9kg00qf 5603 93 Consensus Consensus NNP cord-022526-j9kg00qf 5603 94 Conference Conference NNP cord-022526-j9kg00qf 5603 95 : : : cord-022526-j9kg00qf 5603 96 Definitions definition NNS cord-022526-j9kg00qf 5603 97 for for IN cord-022526-j9kg00qf 5603 98 sepsis sepsis NN cord-022526-j9kg00qf 5603 99 and and CC cord-022526-j9kg00qf 5603 100 organ organ NN cord-022526-j9kg00qf 5603 101 failure failure NN cord-022526-j9kg00qf 5603 102 and and CC cord-022526-j9kg00qf 5603 103 guidelines guideline NNS cord-022526-j9kg00qf 5603 104 for for IN cord-022526-j9kg00qf 5603 105 the the DT cord-022526-j9kg00qf 5603 106 use use NN cord-022526-j9kg00qf 5603 107 of of IN cord-022526-j9kg00qf 5603 108 innovative innovative JJ cord-022526-j9kg00qf 5603 109 therapies therapy NNS cord-022526-j9kg00qf 5603 110 in in IN cord-022526-j9kg00qf 5603 111 sepsis sepsis NN cord-022526-j9kg00qf 5604 1 Sisson Sisson NNP cord-022526-j9kg00qf 5604 2 and and CC cord-022526-j9kg00qf 5604 3 Grossman Grossman NNP cord-022526-j9kg00qf 5604 4 's 's POS cord-022526-j9kg00qf 5604 5 the the DT cord-022526-j9kg00qf 5604 6 anatomy anatomy NN cord-022526-j9kg00qf 5604 7 of of IN cord-022526-j9kg00qf 5604 8 domestic domestic JJ cord-022526-j9kg00qf 5604 9 animals animal NNS cord-022526-j9kg00qf 5605 1 Observational observational JJ cord-022526-j9kg00qf 5605 2 study study NN cord-022526-j9kg00qf 5605 3 of of IN cord-022526-j9kg00qf 5605 4 " " `` cord-022526-j9kg00qf 5605 5 urine urine NN cord-022526-j9kg00qf 5605 6 testing testing NN cord-022526-j9kg00qf 5605 7 " " '' cord-022526-j9kg00qf 5605 8 in in IN cord-022526-j9kg00qf 5605 9 the the DT cord-022526-j9kg00qf 5605 10 horse horse NN cord-022526-j9kg00qf 5605 11 and and CC cord-022526-j9kg00qf 5605 12 donkey donkey NN cord-022526-j9kg00qf 5605 13 stallion stallion NN cord-022526-j9kg00qf 5605 14 Oral oral JJ cord-022526-j9kg00qf 5605 15 examination examination NN cord-022526-j9kg00qf 5605 16 and and CC cord-022526-j9kg00qf 5605 17 diagnosis diagnosis NN cord-022526-j9kg00qf 5605 18 : : : cord-022526-j9kg00qf 5605 19 management management NN cord-022526-j9kg00qf 5605 20 of of IN cord-022526-j9kg00qf 5605 21 oral oral JJ cord-022526-j9kg00qf 5605 22 disease disease NN cord-022526-j9kg00qf 5606 1 Fluoroscopic fluoroscopic JJ cord-022526-j9kg00qf 5606 2 investigations investigation NNS cord-022526-j9kg00qf 5606 3 of of IN cord-022526-j9kg00qf 5606 4 swallowing swallow VBG cord-022526-j9kg00qf 5606 5 in in IN cord-022526-j9kg00qf 5606 6 the the DT cord-022526-j9kg00qf 5606 7 horse horse NN cord-022526-j9kg00qf 5606 8 Esophageal esophageal JJ cord-022526-j9kg00qf 5606 9 dysfunction dysfunction NN cord-022526-j9kg00qf 5606 10 in in IN cord-022526-j9kg00qf 5606 11 a a DT cord-022526-j9kg00qf 5606 12 weanling weanle VBG cord-022526-j9kg00qf 5606 13 thoroughbred thoroughbred NNP cord-022526-j9kg00qf 5606 14 Cervical Cervical NNP cord-022526-j9kg00qf 5606 15 esophagostomy esophagostomy NNP cord-022526-j9kg00qf 5606 16 to to TO cord-022526-j9kg00qf 5606 17 permit permit VB cord-022526-j9kg00qf 5606 18 extraoral extraoral JJ cord-022526-j9kg00qf 5606 19 feeding feeding NN cord-022526-j9kg00qf 5606 20 of of IN cord-022526-j9kg00qf 5606 21 the the DT cord-022526-j9kg00qf 5606 22 horse horse NN cord-022526-j9kg00qf 5606 23 Use use NN cord-022526-j9kg00qf 5606 24 of of IN cord-022526-j9kg00qf 5606 25 a a DT cord-022526-j9kg00qf 5606 26 liquid liquid JJ cord-022526-j9kg00qf 5606 27 diet diet NN cord-022526-j9kg00qf 5606 28 as as IN cord-022526-j9kg00qf 5606 29 the the DT cord-022526-j9kg00qf 5606 30 sole sole JJ cord-022526-j9kg00qf 5606 31 source source NN cord-022526-j9kg00qf 5606 32 of of IN cord-022526-j9kg00qf 5606 33 nutrition nutrition NN cord-022526-j9kg00qf 5606 34 in in IN cord-022526-j9kg00qf 5606 35 six six CD cord-022526-j9kg00qf 5606 36 dysphagic dysphagic JJ cord-022526-j9kg00qf 5606 37 horses horse NNS cord-022526-j9kg00qf 5606 38 and and CC cord-022526-j9kg00qf 5606 39 as as IN cord-022526-j9kg00qf 5606 40 a a DT cord-022526-j9kg00qf 5606 41 dietary dietary JJ cord-022526-j9kg00qf 5606 42 supplement supplement NN cord-022526-j9kg00qf 5606 43 in in IN cord-022526-j9kg00qf 5606 44 seven seven CD cord-022526-j9kg00qf 5606 45 hypophagic hypophagic NNP cord-022526-j9kg00qf 5606 46 horses horse NNS cord-022526-j9kg00qf 5606 47 Acid acid NN cord-022526-j9kg00qf 5606 48 - - HYPH cord-022526-j9kg00qf 5606 49 base base NN cord-022526-j9kg00qf 5606 50 and and CC cord-022526-j9kg00qf 5606 51 electrolyte electrolyte JJ cord-022526-j9kg00qf 5606 52 alterations alteration NNS cord-022526-j9kg00qf 5606 53 associated associate VBN cord-022526-j9kg00qf 5606 54 with with IN cord-022526-j9kg00qf 5606 55 salivary salivary JJ cord-022526-j9kg00qf 5606 56 loss loss NN cord-022526-j9kg00qf 5606 57 in in IN cord-022526-j9kg00qf 5606 58 the the DT cord-022526-j9kg00qf 5606 59 pony pony NN cord-022526-j9kg00qf 5606 60 Dysphagia Dysphagia NNP cord-022526-j9kg00qf 5606 61 caused cause VBD cord-022526-j9kg00qf 5606 62 by by IN cord-022526-j9kg00qf 5606 63 squamous squamous JJ cord-022526-j9kg00qf 5606 64 cell cell NN cord-022526-j9kg00qf 5606 65 carcinoma carcinoma NN cord-022526-j9kg00qf 5606 66 in in IN cord-022526-j9kg00qf 5606 67 2 2 CD cord-022526-j9kg00qf 5606 68 horses horse NNS cord-022526-j9kg00qf 5606 69 Diseases disease NNS cord-022526-j9kg00qf 5606 70 of of IN cord-022526-j9kg00qf 5606 71 the the DT cord-022526-j9kg00qf 5606 72 teeth tooth NNS cord-022526-j9kg00qf 5607 1 Comparative comparative JJ cord-022526-j9kg00qf 5607 2 dental dental JJ cord-022526-j9kg00qf 5607 3 pathology pathology NN cord-022526-j9kg00qf 5607 4 ( ( -LRB- cord-022526-j9kg00qf 5607 5 with with IN cord-022526-j9kg00qf 5607 6 particular particular JJ cord-022526-j9kg00qf 5607 7 reference reference NN cord-022526-j9kg00qf 5607 8 to to IN cord-022526-j9kg00qf 5607 9 caries caries NN cord-022526-j9kg00qf 5607 10 and and CC cord-022526-j9kg00qf 5607 11 paradental paradental JJ cord-022526-j9kg00qf 5607 12 disease disease NN cord-022526-j9kg00qf 5607 13 in in IN cord-022526-j9kg00qf 5607 14 the the DT cord-022526-j9kg00qf 5607 15 horse horse NN cord-022526-j9kg00qf 5607 16 and and CC cord-022526-j9kg00qf 5607 17 the the DT cord-022526-j9kg00qf 5607 18 dog dog NN cord-022526-j9kg00qf 5607 19 ) ) -RRB- cord-022526-j9kg00qf 5608 1 Some some DT cord-022526-j9kg00qf 5608 2 aspects aspect NNS cord-022526-j9kg00qf 5608 3 of of IN cord-022526-j9kg00qf 5608 4 equine equine JJ cord-022526-j9kg00qf 5608 5 dental dental JJ cord-022526-j9kg00qf 5608 6 radiology radiology NNP cord-022526-j9kg00qf 5609 1 Some some DT cord-022526-j9kg00qf 5609 2 aspects aspect NNS cord-022526-j9kg00qf 5609 3 of of IN cord-022526-j9kg00qf 5609 4 equine equine JJ cord-022526-j9kg00qf 5609 5 dental dental JJ cord-022526-j9kg00qf 5609 6 decay decay NN cord-022526-j9kg00qf 5610 1 The the DT cord-022526-j9kg00qf 5610 2 median median JJ cord-022526-j9kg00qf 5610 3 cleft cleft NN cord-022526-j9kg00qf 5610 4 of of IN cord-022526-j9kg00qf 5610 5 the the DT cord-022526-j9kg00qf 5610 6 lower low JJR cord-022526-j9kg00qf 5610 7 lip lip NN cord-022526-j9kg00qf 5610 8 and and CC cord-022526-j9kg00qf 5610 9 mandible mandible NN cord-022526-j9kg00qf 5610 10 and and CC cord-022526-j9kg00qf 5610 11 its -PRON- PRP$ cord-022526-j9kg00qf 5610 12 surgical surgical JJ cord-022526-j9kg00qf 5610 13 correction correction NN cord-022526-j9kg00qf 5610 14 in in IN cord-022526-j9kg00qf 5610 15 a a DT cord-022526-j9kg00qf 5610 16 donkey donkey NN cord-022526-j9kg00qf 5610 17 Sisson Sisson NNP cord-022526-j9kg00qf 5610 18 and and CC cord-022526-j9kg00qf 5610 19 Grossman Grossman NNP cord-022526-j9kg00qf 5610 20 's 's POS cord-022526-j9kg00qf 5610 21 the the DT cord-022526-j9kg00qf 5610 22 anatomy anatomy NN cord-022526-j9kg00qf 5610 23 of of IN cord-022526-j9kg00qf 5610 24 domestic domestic JJ cord-022526-j9kg00qf 5610 25 animals animal NNS cord-022526-j9kg00qf 5610 26 Esophageal esophageal JJ cord-022526-j9kg00qf 5610 27 disorders disorder NNS cord-022526-j9kg00qf 5610 28 of of IN cord-022526-j9kg00qf 5610 29 the the DT cord-022526-j9kg00qf 5610 30 horse horse NN cord-022526-j9kg00qf 5610 31 Esophageal esophageal JJ cord-022526-j9kg00qf 5610 32 disorders disorder NNS cord-022526-j9kg00qf 5610 33 in in IN cord-022526-j9kg00qf 5610 34 61 61 CD cord-022526-j9kg00qf 5610 35 horses horse NNS cord-022526-j9kg00qf 5610 36 : : : cord-022526-j9kg00qf 5610 37 results result NNS cord-022526-j9kg00qf 5610 38 of of IN cord-022526-j9kg00qf 5610 39 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5610 40 and and CC cord-022526-j9kg00qf 5610 41 surgical surgical JJ cord-022526-j9kg00qf 5610 42 management management NN cord-022526-j9kg00qf 5610 43 Recurrent recurrent JJ cord-022526-j9kg00qf 5610 44 esophageal esophageal JJ cord-022526-j9kg00qf 5610 45 obstruction obstruction NN cord-022526-j9kg00qf 5610 46 due due JJ cord-022526-j9kg00qf 5610 47 to to IN cord-022526-j9kg00qf 5610 48 squamous squamous JJ cord-022526-j9kg00qf 5610 49 cell cell NN cord-022526-j9kg00qf 5610 50 carcinoma carcinoma NN cord-022526-j9kg00qf 5610 51 in in IN cord-022526-j9kg00qf 5610 52 a a DT cord-022526-j9kg00qf 5610 53 horse horse NN cord-022526-j9kg00qf 5610 54 Squamous squamous JJ cord-022526-j9kg00qf 5610 55 cell cell NN cord-022526-j9kg00qf 5610 56 carcinoma carcinoma NN cord-022526-j9kg00qf 5610 57 of of IN cord-022526-j9kg00qf 5610 58 the the DT cord-022526-j9kg00qf 5610 59 lower low JJR cord-022526-j9kg00qf 5610 60 cervical cervical JJ cord-022526-j9kg00qf 5610 61 oesophagus oesophagus NN cord-022526-j9kg00qf 5610 62 in in IN cord-022526-j9kg00qf 5610 63 a a DT cord-022526-j9kg00qf 5610 64 pony pony NN cord-022526-j9kg00qf 5610 65 Squamous squamous JJ cord-022526-j9kg00qf 5610 66 cell cell NN cord-022526-j9kg00qf 5610 67 carcinoma carcinoma NN cord-022526-j9kg00qf 5610 68 : : : cord-022526-j9kg00qf 5610 69 an an DT cord-022526-j9kg00qf 5610 70 unusual unusual JJ cord-022526-j9kg00qf 5610 71 cause cause NN cord-022526-j9kg00qf 5610 72 of of IN cord-022526-j9kg00qf 5610 73 choke choke NN cord-022526-j9kg00qf 5610 74 in in RP cord-022526-j9kg00qf 5610 75 a a DT cord-022526-j9kg00qf 5610 76 horse horse NN cord-022526-j9kg00qf 5610 77 Megaesophagus Megaesophagus NNP cord-022526-j9kg00qf 5610 78 and and CC cord-022526-j9kg00qf 5610 79 aspiration aspiration NN cord-022526-j9kg00qf 5610 80 pneumonia pneumonia NN cord-022526-j9kg00qf 5610 81 secondary secondary JJ cord-022526-j9kg00qf 5610 82 to to IN cord-022526-j9kg00qf 5610 83 gastric gastric JJ cord-022526-j9kg00qf 5610 84 ulceration ulceration NN cord-022526-j9kg00qf 5610 85 in in IN cord-022526-j9kg00qf 5610 86 a a DT cord-022526-j9kg00qf 5610 87 foal foal NN cord-022526-j9kg00qf 5610 88 Persistent persistent JJ cord-022526-j9kg00qf 5610 89 right right JJ cord-022526-j9kg00qf 5610 90 aortic aortic JJ cord-022526-j9kg00qf 5610 91 arch arch NN cord-022526-j9kg00qf 5610 92 in in IN cord-022526-j9kg00qf 5610 93 a a DT cord-022526-j9kg00qf 5610 94 yearling yearling NN cord-022526-j9kg00qf 5610 95 horse horse NN cord-022526-j9kg00qf 5610 96 Intramural Intramural NNP cord-022526-j9kg00qf 5610 97 esophageal esophageal JJ cord-022526-j9kg00qf 5610 98 cyst cyst NN cord-022526-j9kg00qf 5610 99 in in IN cord-022526-j9kg00qf 5610 100 a a DT cord-022526-j9kg00qf 5610 101 horse horse NN cord-022526-j9kg00qf 5610 102 Surgical surgical JJ cord-022526-j9kg00qf 5610 103 correction correction NN cord-022526-j9kg00qf 5610 104 of of IN cord-022526-j9kg00qf 5610 105 esophageal esophageal JJ cord-022526-j9kg00qf 5610 106 diverticulum diverticulum NN cord-022526-j9kg00qf 5610 107 in in IN cord-022526-j9kg00qf 5610 108 a a DT cord-022526-j9kg00qf 5610 109 horse horse NN cord-022526-j9kg00qf 5611 1 On on IN cord-022526-j9kg00qf 5611 2 the the DT cord-022526-j9kg00qf 5611 3 true true JJ cord-022526-j9kg00qf 5611 4 definition definition NN cord-022526-j9kg00qf 5611 5 of of IN cord-022526-j9kg00qf 5611 6 dysphagia dysphagia NNP cord-022526-j9kg00qf 5611 7 Retrieval Retrieval NNP cord-022526-j9kg00qf 5611 8 of of IN cord-022526-j9kg00qf 5611 9 an an DT cord-022526-j9kg00qf 5611 10 esophageal esophageal JJ cord-022526-j9kg00qf 5611 11 foreign foreign JJ cord-022526-j9kg00qf 5611 12 body body NN cord-022526-j9kg00qf 5611 13 in in IN cord-022526-j9kg00qf 5611 14 a a DT cord-022526-j9kg00qf 5611 15 horse horse NN cord-022526-j9kg00qf 5611 16 Dysphagia Dysphagia NNP cord-022526-j9kg00qf 5611 17 caused cause VBN cord-022526-j9kg00qf 5611 18 by by IN cord-022526-j9kg00qf 5611 19 squamous squamous JJ cord-022526-j9kg00qf 5611 20 cell cell NN cord-022526-j9kg00qf 5611 21 carcinoma carcinoma NN cord-022526-j9kg00qf 5611 22 in in IN cord-022526-j9kg00qf 5611 23 two two CD cord-022526-j9kg00qf 5611 24 horses horse NNS cord-022526-j9kg00qf 5611 25 Peptic peptic JJ cord-022526-j9kg00qf 5611 26 ulcer ulcer NN cord-022526-j9kg00qf 5611 27 pathophysiology pathophysiology NN cord-022526-j9kg00qf 5611 28 Recommendations recommendation NNS cord-022526-j9kg00qf 5611 29 for for IN cord-022526-j9kg00qf 5611 30 the the DT cord-022526-j9kg00qf 5611 31 diagnosis diagnosis NN cord-022526-j9kg00qf 5611 32 and and CC cord-022526-j9kg00qf 5611 33 treatment treatment NN cord-022526-j9kg00qf 5611 34 of of IN cord-022526-j9kg00qf 5611 35 equine equine JJ cord-022526-j9kg00qf 5611 36 gastric gastric JJ cord-022526-j9kg00qf 5611 37 ulcer ulcer NN cord-022526-j9kg00qf 5611 38 syndrome syndrome NN cord-022526-j9kg00qf 5611 39 ( ( -LRB- cord-022526-j9kg00qf 5611 40 EGUS EGUS NNP cord-022526-j9kg00qf 5611 41 ) ) -RRB- cord-022526-j9kg00qf 5611 42 Gastric gastric JJ cord-022526-j9kg00qf 5611 43 ulcers ulcer NNS cord-022526-j9kg00qf 5611 44 in in IN cord-022526-j9kg00qf 5611 45 horses horse NNS cord-022526-j9kg00qf 5611 46 : : : cord-022526-j9kg00qf 5611 47 a a DT cord-022526-j9kg00qf 5611 48 comparison comparison NN cord-022526-j9kg00qf 5611 49 of of IN cord-022526-j9kg00qf 5611 50 endoscopic endoscopic JJ cord-022526-j9kg00qf 5611 51 findings finding NNS cord-022526-j9kg00qf 5611 52 in in IN cord-022526-j9kg00qf 5611 53 horses horse NNS cord-022526-j9kg00qf 5611 54 with with IN cord-022526-j9kg00qf 5611 55 and and CC cord-022526-j9kg00qf 5611 56 without without IN cord-022526-j9kg00qf 5611 57 clinical clinical JJ cord-022526-j9kg00qf 5611 58 signs sign NNS cord-022526-j9kg00qf 5612 1 Pipers piper NNS cord-022526-j9kg00qf 5613 1 FS FS NNP cord-022526-j9kg00qf 5613 2 et et NNP cord-022526-j9kg00qf 5613 3 al al NNP cord-022526-j9kg00qf 5613 4 : : : cord-022526-j9kg00qf 5614 1 Factors factor NNS cord-022526-j9kg00qf 5614 2 associated associate VBN cord-022526-j9kg00qf 5614 3 with with IN cord-022526-j9kg00qf 5614 4 gastric gastric JJ cord-022526-j9kg00qf 5614 5 lesions lesion NNS cord-022526-j9kg00qf 5614 6 in in IN cord-022526-j9kg00qf 5614 7 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5614 8 racehorses racehorse NNS cord-022526-j9kg00qf 5614 9 Cross Cross NNP cord-022526-j9kg00qf 5614 10 - - JJ cord-022526-j9kg00qf 5614 11 sectional sectional JJ cord-022526-j9kg00qf 5614 12 study study NN cord-022526-j9kg00qf 5614 13 of of IN cord-022526-j9kg00qf 5614 14 gastric gastric JJ cord-022526-j9kg00qf 5614 15 ulcers ulcer NNS cord-022526-j9kg00qf 5614 16 of of IN cord-022526-j9kg00qf 5614 17 the the DT cord-022526-j9kg00qf 5614 18 squamous squamous JJ cord-022526-j9kg00qf 5614 19 mucosa mucosa NN cord-022526-j9kg00qf 5614 20 in in IN cord-022526-j9kg00qf 5614 21 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5614 22 racehorses racehorse NNS cord-022526-j9kg00qf 5614 23 Gastric gastric JJ cord-022526-j9kg00qf 5614 24 ulceration ulceration NN cord-022526-j9kg00qf 5614 25 in in IN cord-022526-j9kg00qf 5614 26 mature mature JJ cord-022526-j9kg00qf 5614 27 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5614 28 horses horse NNS cord-022526-j9kg00qf 5615 1 Epidemiological epidemiological JJ cord-022526-j9kg00qf 5615 2 study study NN cord-022526-j9kg00qf 5615 3 of of IN cord-022526-j9kg00qf 5615 4 gastric gastric JJ cord-022526-j9kg00qf 5615 5 ulceration ulceration NN cord-022526-j9kg00qf 5615 6 in in IN cord-022526-j9kg00qf 5615 7 the the DT cord-022526-j9kg00qf 5615 8 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5615 9 racehorse racehorse NN cord-022526-j9kg00qf 5615 10 : : : cord-022526-j9kg00qf 5615 11 202 202 CD cord-022526-j9kg00qf 5615 12 horses horse NNS cord-022526-j9kg00qf 5615 13 1992 1992 CD cord-022526-j9kg00qf 5615 14 - - SYM cord-022526-j9kg00qf 5615 15 1993 1993 CD cord-022526-j9kg00qf 5615 16 Endoscopic endoscopic JJ cord-022526-j9kg00qf 5615 17 evaluation evaluation NN cord-022526-j9kg00qf 5615 18 of of IN cord-022526-j9kg00qf 5615 19 the the DT cord-022526-j9kg00qf 5615 20 relationship relationship NN cord-022526-j9kg00qf 5615 21 between between IN cord-022526-j9kg00qf 5615 22 training training NN cord-022526-j9kg00qf 5615 23 , , , cord-022526-j9kg00qf 5615 24 racing racing NN cord-022526-j9kg00qf 5615 25 , , , cord-022526-j9kg00qf 5615 26 and and CC cord-022526-j9kg00qf 5615 27 gastric gastric JJ cord-022526-j9kg00qf 5615 28 ulcers ulcer NNS cord-022526-j9kg00qf 5615 29 Prevalence prevalence NN cord-022526-j9kg00qf 5615 30 of of IN cord-022526-j9kg00qf 5615 31 gastric gastric JJ cord-022526-j9kg00qf 5615 32 ulcers ulcer NNS cord-022526-j9kg00qf 5615 33 in in IN cord-022526-j9kg00qf 5615 34 show show NN cord-022526-j9kg00qf 5615 35 horses horse NNS cord-022526-j9kg00qf 5616 1 Postmortem postmortem JJ cord-022526-j9kg00qf 5616 2 findings finding NNS cord-022526-j9kg00qf 5616 3 of of IN cord-022526-j9kg00qf 5616 4 gastric gastric JJ cord-022526-j9kg00qf 5616 5 ulcers ulcer NNS cord-022526-j9kg00qf 5616 6 in in IN cord-022526-j9kg00qf 5616 7 Swedish swedish JJ cord-022526-j9kg00qf 5616 8 horses horse NNS cord-022526-j9kg00qf 5616 9 older old JJR cord-022526-j9kg00qf 5616 10 than than IN cord-022526-j9kg00qf 5616 11 age age NN cord-022526-j9kg00qf 5616 12 one one CD cord-022526-j9kg00qf 5616 13 year year NN cord-022526-j9kg00qf 5616 14 : : : cord-022526-j9kg00qf 5616 15 a a DT cord-022526-j9kg00qf 5616 16 retrospective retrospective JJ cord-022526-j9kg00qf 5616 17 study study NN cord-022526-j9kg00qf 5616 18 of of IN cord-022526-j9kg00qf 5616 19 3715 3715 CD cord-022526-j9kg00qf 5616 20 horses horse NNS cord-022526-j9kg00qf 5616 21 ( ( -LRB- cord-022526-j9kg00qf 5616 22 1924 1924 CD cord-022526-j9kg00qf 5616 23 - - SYM cord-022526-j9kg00qf 5616 24 1996 1996 CD cord-022526-j9kg00qf 5616 25 ) ) -RRB- cord-022526-j9kg00qf 5617 1 Endoscopic endoscopic JJ cord-022526-j9kg00qf 5617 2 findings finding NNS cord-022526-j9kg00qf 5617 3 of of IN cord-022526-j9kg00qf 5617 4 the the DT cord-022526-j9kg00qf 5617 5 gastric gastric JJ cord-022526-j9kg00qf 5617 6 antrum antrum NN cord-022526-j9kg00qf 5617 7 and and CC cord-022526-j9kg00qf 5617 8 pylorus pylorus NN cord-022526-j9kg00qf 5617 9 in in IN cord-022526-j9kg00qf 5617 10 horses horse NNS cord-022526-j9kg00qf 5617 11 : : : cord-022526-j9kg00qf 5617 12 162 162 CD cord-022526-j9kg00qf 5617 13 cases case NNS cord-022526-j9kg00qf 5617 14 Gastric gastric JJ cord-022526-j9kg00qf 5617 15 and and CC cord-022526-j9kg00qf 5617 16 duodenal duodenal JJ cord-022526-j9kg00qf 5617 17 ulcers ulcer NNS cord-022526-j9kg00qf 5617 18 in in IN cord-022526-j9kg00qf 5617 19 foals foal NNS cord-022526-j9kg00qf 5617 20 : : : cord-022526-j9kg00qf 5617 21 a a DT cord-022526-j9kg00qf 5617 22 retrospective retrospective JJ cord-022526-j9kg00qf 5617 23 study study NN cord-022526-j9kg00qf 5617 24 Endoscopic endoscopic JJ cord-022526-j9kg00qf 5617 25 appearance appearance NN cord-022526-j9kg00qf 5617 26 of of IN cord-022526-j9kg00qf 5617 27 gastric gastric JJ cord-022526-j9kg00qf 5617 28 lesions lesion NNS cord-022526-j9kg00qf 5617 29 in in IN cord-022526-j9kg00qf 5617 30 foals foal NNS cord-022526-j9kg00qf 5617 31 : : : cord-022526-j9kg00qf 5617 32 94 94 CD cord-022526-j9kg00qf 5617 33 cases case NNS cord-022526-j9kg00qf 5617 34 Prevalence prevalence NN cord-022526-j9kg00qf 5617 35 of of IN cord-022526-j9kg00qf 5617 36 gastric gastric JJ cord-022526-j9kg00qf 5617 37 lesions lesion NNS cord-022526-j9kg00qf 5617 38 in in IN cord-022526-j9kg00qf 5617 39 foals foal NNS cord-022526-j9kg00qf 5617 40 without without IN cord-022526-j9kg00qf 5617 41 signs sign NNS cord-022526-j9kg00qf 5617 42 of of IN cord-022526-j9kg00qf 5617 43 gastric gastric JJ cord-022526-j9kg00qf 5617 44 disease disease NN cord-022526-j9kg00qf 5617 45 : : : cord-022526-j9kg00qf 5617 46 an an DT cord-022526-j9kg00qf 5617 47 endoscopic endoscopic NN cord-022526-j9kg00qf 5617 48 survey survey NN cord-022526-j9kg00qf 5617 49 Gastroduodenal Gastroduodenal NNP cord-022526-j9kg00qf 5617 50 ulceration ulceration NN cord-022526-j9kg00qf 5617 51 in in IN cord-022526-j9kg00qf 5617 52 foals foal NNS cord-022526-j9kg00qf 5617 53 Regional regional JJ cord-022526-j9kg00qf 5617 54 gastric gastric JJ cord-022526-j9kg00qf 5617 55 pH pH NNP cord-022526-j9kg00qf 5617 56 measurement measurement NN cord-022526-j9kg00qf 5617 57 in in IN cord-022526-j9kg00qf 5617 58 horses horse NNS cord-022526-j9kg00qf 5617 59 and and CC cord-022526-j9kg00qf 5617 60 foals foal NNS cord-022526-j9kg00qf 5617 61 Peptic peptic JJ cord-022526-j9kg00qf 5617 62 ulcer ulcer NN cord-022526-j9kg00qf 5617 63 disease disease NN cord-022526-j9kg00qf 5617 64 in in IN cord-022526-j9kg00qf 5617 65 the the DT cord-022526-j9kg00qf 5617 66 pediatric pediatric JJ cord-022526-j9kg00qf 5617 67 population population NN cord-022526-j9kg00qf 5618 1 Is be VBZ cord-022526-j9kg00qf 5618 2 Helicobacter Helicobacter NNP cord-022526-j9kg00qf 5618 3 ( ( -LRB- cord-022526-j9kg00qf 5618 4 Campylobacter Campylobacter NNP cord-022526-j9kg00qf 5618 5 ) ) -RRB- cord-022526-j9kg00qf 5618 6 pylori pylori NN cord-022526-j9kg00qf 5618 7 associated associate VBN cord-022526-j9kg00qf 5618 8 with with IN cord-022526-j9kg00qf 5618 9 gastritis gastritis NN cord-022526-j9kg00qf 5618 10 / / SYM cord-022526-j9kg00qf 5618 11 ulcer ulcer NN cord-022526-j9kg00qf 5618 12 disease disease NN cord-022526-j9kg00qf 5618 13 in in IN cord-022526-j9kg00qf 5618 14 asymptomatic asymptomatic JJ cord-022526-j9kg00qf 5618 15 foals foal NNS cord-022526-j9kg00qf 5618 16 ? ? . cord-022526-j9kg00qf 5619 1 Aetiopathogenesis aetiopathogenesis NN cord-022526-j9kg00qf 5619 2 and and CC cord-022526-j9kg00qf 5619 3 treatment treatment NN cord-022526-j9kg00qf 5619 4 of of IN cord-022526-j9kg00qf 5619 5 peptic peptic JJ cord-022526-j9kg00qf 5619 6 ulcer ulcer NN cord-022526-j9kg00qf 5619 7 in in IN cord-022526-j9kg00qf 5619 8 the the DT cord-022526-j9kg00qf 5619 9 horse horse NN cord-022526-j9kg00qf 5619 10 : : : cord-022526-j9kg00qf 5619 11 a a DT cord-022526-j9kg00qf 5619 12 comparative comparative JJ cord-022526-j9kg00qf 5619 13 review review NN cord-022526-j9kg00qf 5619 14 Evidence evidence NN cord-022526-j9kg00qf 5619 15 of of IN cord-022526-j9kg00qf 5619 16 Helicobacter Helicobacter NNP cord-022526-j9kg00qf 5619 17 infection infection NN cord-022526-j9kg00qf 5619 18 in in IN cord-022526-j9kg00qf 5619 19 the the DT cord-022526-j9kg00qf 5619 20 horse horse NN cord-022526-j9kg00qf 5619 21 . . . cord-022526-j9kg00qf 5620 1 Proceedings proceeding NNS cord-022526-j9kg00qf 5620 2 of of IN cord-022526-j9kg00qf 5620 3 the the DT cord-022526-j9kg00qf 5620 4 Society Society NNP cord-022526-j9kg00qf 5620 5 for for IN cord-022526-j9kg00qf 5620 6 Microbiologists Microbiologists NNPS cord-022526-j9kg00qf 5620 7 Comparative Comparative NNP cord-022526-j9kg00qf 5620 8 pathophysiology pathophysiology NN cord-022526-j9kg00qf 5620 9 of of IN cord-022526-j9kg00qf 5620 10 nonglandular nonglandular JJ cord-022526-j9kg00qf 5620 11 ulcer ulcer NN cord-022526-j9kg00qf 5620 12 disease disease NN cord-022526-j9kg00qf 5620 13 : : : cord-022526-j9kg00qf 5620 14 a a DT cord-022526-j9kg00qf 5620 15 review review NN cord-022526-j9kg00qf 5620 16 of of IN cord-022526-j9kg00qf 5620 17 experimental experimental JJ cord-022526-j9kg00qf 5620 18 studies study NNS cord-022526-j9kg00qf 5620 19 SECTION section NN cord-022526-j9kg00qf 5620 20 13.10 13.10 CD cord-022526-j9kg00qf 5620 21 Diseases disease NNS cord-022526-j9kg00qf 5620 22 of of IN cord-022526-j9kg00qf 5620 23 the the DT cord-022526-j9kg00qf 5620 24 Stomach stomach NN cord-022526-j9kg00qf 5621 1 REFERENCES reference NNS cord-022526-j9kg00qf 5621 2 1 1 CD cord-022526-j9kg00qf 5621 3 . . . cord-022526-j9kg00qf 5622 1 Blackwell Blackwell NNP cord-022526-j9kg00qf 5622 2 RB RB NNP cord-022526-j9kg00qf 5622 3 , , , cord-022526-j9kg00qf 5622 4 White White NNP cord-022526-j9kg00qf 5622 5 NA NA NNP cord-022526-j9kg00qf 5622 6 : : : cord-022526-j9kg00qf 5622 7 Duodenitis Duodenitis NNP cord-022526-j9kg00qf 5622 8 - - HYPH cord-022526-j9kg00qf 5622 9 proximal proximal JJ cord-022526-j9kg00qf 5622 10 jejunitis jejunitis NN cord-022526-j9kg00qf 5622 11 in in IN cord-022526-j9kg00qf 5622 12 the the DT cord-022526-j9kg00qf 5622 13 horse horse NN cord-022526-j9kg00qf 5622 14 Hemorrhagic Hemorrhagic NNP cord-022526-j9kg00qf 5622 15 fibrinonecrotic fibrinonecrotic JJ cord-022526-j9kg00qf 5622 16 duodenitis duodenitis NN cord-022526-j9kg00qf 5622 17 - - HYPH cord-022526-j9kg00qf 5622 18 proximal proximal JJ cord-022526-j9kg00qf 5622 19 jejunitis jejunitis NN cord-022526-j9kg00qf 5622 20 in in IN cord-022526-j9kg00qf 5622 21 horses horse NNS cord-022526-j9kg00qf 5622 22 : : : cord-022526-j9kg00qf 5622 23 20 20 CD cord-022526-j9kg00qf 5622 24 cases case NNS cord-022526-j9kg00qf 5623 1 Comparison comparison NN cord-022526-j9kg00qf 5623 2 of of IN cord-022526-j9kg00qf 5623 3 duodenitis duodenitis NN cord-022526-j9kg00qf 5623 4 - - HYPH cord-022526-j9kg00qf 5623 5 proximal proximal JJ cord-022526-j9kg00qf 5623 6 jejunitis jejunitis NN cord-022526-j9kg00qf 5623 7 and and CC cord-022526-j9kg00qf 5623 8 small small JJ cord-022526-j9kg00qf 5623 9 intestinal intestinal JJ cord-022526-j9kg00qf 5623 10 obstruction obstruction NN cord-022526-j9kg00qf 5623 11 in in IN cord-022526-j9kg00qf 5623 12 horses horse NNS cord-022526-j9kg00qf 5623 13 : : : cord-022526-j9kg00qf 5623 14 68 68 CD cord-022526-j9kg00qf 5623 15 cases case NNS cord-022526-j9kg00qf 5623 16 ( ( -LRB- cord-022526-j9kg00qf 5623 17 1977 1977 CD cord-022526-j9kg00qf 5623 18 - - SYM cord-022526-j9kg00qf 5623 19 1985 1985 CD cord-022526-j9kg00qf 5623 20 ) ) -RRB- cord-022526-j9kg00qf 5624 1 Prognostic prognostic JJ cord-022526-j9kg00qf 5624 2 indicators indicator NNS cord-022526-j9kg00qf 5624 3 for for IN cord-022526-j9kg00qf 5624 4 horses horse NNS cord-022526-j9kg00qf 5624 5 with with IN cord-022526-j9kg00qf 5624 6 duodenitis duodenitis NN cord-022526-j9kg00qf 5624 7 - - HYPH cord-022526-j9kg00qf 5624 8 proximal proximal JJ cord-022526-j9kg00qf 5624 9 jejunitis jejunitis NN cord-022526-j9kg00qf 5624 10 : : : cord-022526-j9kg00qf 5624 11 75 75 CD cord-022526-j9kg00qf 5624 12 horses horse NNS cord-022526-j9kg00qf 5624 13 ( ( -LRB- cord-022526-j9kg00qf 5624 14 1985 1985 CD cord-022526-j9kg00qf 5624 15 - - SYM cord-022526-j9kg00qf 5624 16 1989 1989 CD cord-022526-j9kg00qf 5624 17 ) ) -RRB- cord-022526-j9kg00qf 5625 1 Duodenitis Duodenitis NNP cord-022526-j9kg00qf 5625 2 - - HYPH cord-022526-j9kg00qf 5625 3 proximal proximal JJ cord-022526-j9kg00qf 5625 4 jejunitis jejunitis NN cord-022526-j9kg00qf 5625 5 Integrative Integrative NNP cord-022526-j9kg00qf 5625 6 immunophysiology immunophysiology NN cord-022526-j9kg00qf 5625 7 in in IN cord-022526-j9kg00qf 5625 8 the the DT cord-022526-j9kg00qf 5625 9 intestinal intestinal JJ cord-022526-j9kg00qf 5625 10 mucosa mucosa NN cord-022526-j9kg00qf 5625 11 Immunophysiology Immunophysiology NNP cord-022526-j9kg00qf 5625 12 of of IN cord-022526-j9kg00qf 5625 13 intestinal intestinal JJ cord-022526-j9kg00qf 5625 14 electrolyte electrolyte NN cord-022526-j9kg00qf 5625 15 transport transport NN cord-022526-j9kg00qf 5625 16 Peritoneal peritoneal NN cord-022526-j9kg00qf 5625 17 fluid fluid JJ cord-022526-j9kg00qf 5625 18 constituents constituent NNS cord-022526-j9kg00qf 5625 19 in in IN cord-022526-j9kg00qf 5625 20 horse horse NN cord-022526-j9kg00qf 5625 21 with with IN cord-022526-j9kg00qf 5625 22 colic colic NN cord-022526-j9kg00qf 5625 23 due due IN cord-022526-j9kg00qf 5625 24 to to IN cord-022526-j9kg00qf 5625 25 small small JJ cord-022526-j9kg00qf 5625 26 intestinal intestinal JJ cord-022526-j9kg00qf 5625 27 disease disease NN cord-022526-j9kg00qf 5625 28 Modification modification NN cord-022526-j9kg00qf 5625 29 of of IN cord-022526-j9kg00qf 5625 30 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5625 31 motility motility NN cord-022526-j9kg00qf 5625 32 in in IN cord-022526-j9kg00qf 5625 33 horses horse NNS cord-022526-j9kg00qf 5625 34 . . . cord-022526-j9kg00qf 5626 1 Proceedings proceeding NNS cord-022526-j9kg00qf 5626 2 of of IN cord-022526-j9kg00qf 5626 3 the the DT cord-022526-j9kg00qf 5626 4 eighteenth eighteenth JJ cord-022526-j9kg00qf 5626 5 annual annual JJ cord-022526-j9kg00qf 5626 6 forum forum NN cord-022526-j9kg00qf 5626 7 of of IN cord-022526-j9kg00qf 5626 8 the the DT cord-022526-j9kg00qf 5626 9 American American NNP cord-022526-j9kg00qf 5626 10 College College NNP cord-022526-j9kg00qf 5626 11 of of IN cord-022526-j9kg00qf 5626 12 Veterinary Veterinary NNP cord-022526-j9kg00qf 5626 13 Internal Internal NNP cord-022526-j9kg00qf 5626 14 Medicine Medicine NNP cord-022526-j9kg00qf 5626 15 Haemodynamic Haemodynamic NNP cord-022526-j9kg00qf 5626 16 effects effect NNS cord-022526-j9kg00qf 5626 17 of of IN cord-022526-j9kg00qf 5626 18 small small JJ cord-022526-j9kg00qf 5626 19 volume volume NN cord-022526-j9kg00qf 5626 20 hypertonic hypertonic NN cord-022526-j9kg00qf 5626 21 saline saline NN cord-022526-j9kg00qf 5626 22 in in IN cord-022526-j9kg00qf 5626 23 experimentally experimentally RB cord-022526-j9kg00qf 5626 24 induced induce VBN cord-022526-j9kg00qf 5626 25 haemorrhagic haemorrhagic JJ cord-022526-j9kg00qf 5626 26 shock shock NN cord-022526-j9kg00qf 5626 27 Equine equine JJ cord-022526-j9kg00qf 5626 28 proliferative proliferative JJ cord-022526-j9kg00qf 5626 29 enteropathy enteropathy NN cord-022526-j9kg00qf 5626 30 : : : cord-022526-j9kg00qf 5626 31 a a DT cord-022526-j9kg00qf 5626 32 cause cause NN cord-022526-j9kg00qf 5626 33 of of IN cord-022526-j9kg00qf 5626 34 weight weight NN cord-022526-j9kg00qf 5626 35 loss loss NN cord-022526-j9kg00qf 5626 36 , , , cord-022526-j9kg00qf 5626 37 colic colic NN cord-022526-j9kg00qf 5626 38 , , , cord-022526-j9kg00qf 5626 39 diarrhea diarrhea NN cord-022526-j9kg00qf 5626 40 and and CC cord-022526-j9kg00qf 5626 41 hypoproteinemia hypoproteinemia NN cord-022526-j9kg00qf 5626 42 in in IN cord-022526-j9kg00qf 5626 43 foals foal NNS cord-022526-j9kg00qf 5626 44 on on IN cord-022526-j9kg00qf 5626 45 three three CD cord-022526-j9kg00qf 5626 46 breeding breeding NN cord-022526-j9kg00qf 5626 47 farms farm NNS cord-022526-j9kg00qf 5626 48 in in IN cord-022526-j9kg00qf 5626 49 Canada Canada NNP cord-022526-j9kg00qf 5626 50 Chronic Chronic NNP cord-022526-j9kg00qf 5626 51 inflammatory inflammatory JJ cord-022526-j9kg00qf 5626 52 and and CC cord-022526-j9kg00qf 5626 53 lymphoproliferative lymphoproliferative JJ cord-022526-j9kg00qf 5626 54 lesions lesion NNS cord-022526-j9kg00qf 5626 55 of of IN cord-022526-j9kg00qf 5626 56 the the DT cord-022526-j9kg00qf 5626 57 equine equine JJ cord-022526-j9kg00qf 5626 58 small small JJ cord-022526-j9kg00qf 5626 59 intestine intestine NN cord-022526-j9kg00qf 5626 60 AA AA NNP cord-022526-j9kg00qf 5626 61 amyloid amyloid NN cord-022526-j9kg00qf 5626 62 - - HYPH cord-022526-j9kg00qf 5626 63 associated associate VBN cord-022526-j9kg00qf 5626 64 gastroenteropathy gastroenteropathy NNP cord-022526-j9kg00qf 5626 65 in in IN cord-022526-j9kg00qf 5626 66 a a DT cord-022526-j9kg00qf 5626 67 horse horse NN cord-022526-j9kg00qf 5626 68 Malabsorption malabsorption NN cord-022526-j9kg00qf 5626 69 in in IN cord-022526-j9kg00qf 5626 70 the the DT cord-022526-j9kg00qf 5626 71 horse horse NN cord-022526-j9kg00qf 5626 72 associated associate VBN cord-022526-j9kg00qf 5626 73 with with IN cord-022526-j9kg00qf 5626 74 alimentary alimentary JJ cord-022526-j9kg00qf 5626 75 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5626 76 Clinical clinical JJ cord-022526-j9kg00qf 5626 77 aspects aspect NNS cord-022526-j9kg00qf 5626 78 of of IN cord-022526-j9kg00qf 5626 79 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5626 80 in in IN cord-022526-j9kg00qf 5626 81 the the DT cord-022526-j9kg00qf 5626 82 horse horse NN cord-022526-j9kg00qf 5626 83 : : : cord-022526-j9kg00qf 5626 84 a a DT cord-022526-j9kg00qf 5626 85 clinical clinical JJ cord-022526-j9kg00qf 5626 86 report report NN cord-022526-j9kg00qf 5626 87 of of IN cord-022526-j9kg00qf 5626 88 16 16 CD cord-022526-j9kg00qf 5626 89 cases case NNS cord-022526-j9kg00qf 5626 90 Alimentary alimentary JJ cord-022526-j9kg00qf 5626 91 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 5626 92 in in IN cord-022526-j9kg00qf 5626 93 the the DT cord-022526-j9kg00qf 5626 94 horse horse NN cord-022526-j9kg00qf 5626 95 Equine equine JJ cord-022526-j9kg00qf 5626 96 granulomatous granulomatous JJ cord-022526-j9kg00qf 5626 97 enteritis enteritis NN cord-022526-j9kg00qf 5626 98 Clinical clinical JJ cord-022526-j9kg00qf 5626 99 and and CC cord-022526-j9kg00qf 5626 100 pathophysiological pathophysiological JJ cord-022526-j9kg00qf 5626 101 features feature NNS cord-022526-j9kg00qf 5626 102 of of IN cord-022526-j9kg00qf 5626 103 granulomatous granulomatous JJ cord-022526-j9kg00qf 5626 104 enteritis enteritis NN cord-022526-j9kg00qf 5626 105 and and CC cord-022526-j9kg00qf 5626 106 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5626 107 granulomatosis granulomatosis NN cord-022526-j9kg00qf 5626 108 in in IN cord-022526-j9kg00qf 5626 109 the the DT cord-022526-j9kg00qf 5626 110 horse horse NN cord-022526-j9kg00qf 5626 111 Chronic Chronic NNP cord-022526-j9kg00qf 5626 112 idiopathic idiopathic JJ cord-022526-j9kg00qf 5626 113 inflammatory inflammatory JJ cord-022526-j9kg00qf 5626 114 bowel bowel NN cord-022526-j9kg00qf 5626 115 diseases disease NNS cord-022526-j9kg00qf 5626 116 of of IN cord-022526-j9kg00qf 5626 117 the the DT cord-022526-j9kg00qf 5626 118 horse horse NN cord-022526-j9kg00qf 5626 119 Pathology pathology NN cord-022526-j9kg00qf 5626 120 of of IN cord-022526-j9kg00qf 5626 121 equine equine JJ cord-022526-j9kg00qf 5626 122 granulomatous granulomatous JJ cord-022526-j9kg00qf 5626 123 enteritis enteritis NN cord-022526-j9kg00qf 5626 124 Rectal rectal JJ cord-022526-j9kg00qf 5626 125 biopsy biopsy NN cord-022526-j9kg00qf 5626 126 diagnosis diagnosis NN cord-022526-j9kg00qf 5626 127 in in IN cord-022526-j9kg00qf 5626 128 horses horse NNS cord-022526-j9kg00qf 5626 129 with with IN cord-022526-j9kg00qf 5626 130 clinical clinical JJ cord-022526-j9kg00qf 5626 131 signs sign NNS cord-022526-j9kg00qf 5626 132 of of IN cord-022526-j9kg00qf 5626 133 intestinal intestinal JJ cord-022526-j9kg00qf 5626 134 disorders disorder NNS cord-022526-j9kg00qf 5626 135 : : : cord-022526-j9kg00qf 5626 136 a a DT cord-022526-j9kg00qf 5626 137 retrospective retrospective JJ cord-022526-j9kg00qf 5626 138 study study NN cord-022526-j9kg00qf 5626 139 of of IN cord-022526-j9kg00qf 5626 140 116 116 CD cord-022526-j9kg00qf 5626 141 cases case NNS cord-022526-j9kg00qf 5626 142 Chronic chronic JJ cord-022526-j9kg00qf 5626 143 enteritis enteritis NN cord-022526-j9kg00qf 5626 144 associated associate VBN cord-022526-j9kg00qf 5626 145 with with IN cord-022526-j9kg00qf 5626 146 malabsorption malabsorption NN cord-022526-j9kg00qf 5626 147 and and CC cord-022526-j9kg00qf 5626 148 protein protein NN cord-022526-j9kg00qf 5626 149 - - HYPH cord-022526-j9kg00qf 5626 150 losing lose VBG cord-022526-j9kg00qf 5626 151 enteropathy enteropathy NN cord-022526-j9kg00qf 5626 152 in in IN cord-022526-j9kg00qf 5626 153 the the DT cord-022526-j9kg00qf 5626 154 horse horse NN cord-022526-j9kg00qf 5626 155 Clinical clinical JJ cord-022526-j9kg00qf 5626 156 remission remission NN cord-022526-j9kg00qf 5626 157 of of IN cord-022526-j9kg00qf 5626 158 granulomatous granulomatous JJ cord-022526-j9kg00qf 5626 159 enteritis enteritis NN cord-022526-j9kg00qf 5626 160 in in IN cord-022526-j9kg00qf 5626 161 a a DT cord-022526-j9kg00qf 5626 162 standardbred standardbred JJ cord-022526-j9kg00qf 5626 163 gelding gelding NN cord-022526-j9kg00qf 5626 164 following follow VBG cord-022526-j9kg00qf 5626 165 long long JJ cord-022526-j9kg00qf 5626 166 term term NN cord-022526-j9kg00qf 5626 167 dexamethasone dexamethasone NNP cord-022526-j9kg00qf 5626 168 administration administration NN cord-022526-j9kg00qf 5626 169 Granulomatous granulomatous JJ cord-022526-j9kg00qf 5626 170 enteritis enteritis NN cord-022526-j9kg00qf 5626 171 in in IN cord-022526-j9kg00qf 5626 172 nine nine CD cord-022526-j9kg00qf 5626 173 horses horse NNS cord-022526-j9kg00qf 5627 1 A a DT cord-022526-j9kg00qf 5627 2 cluster cluster NN cord-022526-j9kg00qf 5627 3 of of IN cord-022526-j9kg00qf 5627 4 granulomatous granulomatous JJ cord-022526-j9kg00qf 5627 5 enteritis enteritis NN cord-022526-j9kg00qf 5627 6 cases case NNS cord-022526-j9kg00qf 5627 7 : : : cord-022526-j9kg00qf 5627 8 the the DT cord-022526-j9kg00qf 5627 9 link link NN cord-022526-j9kg00qf 5627 10 with with IN cord-022526-j9kg00qf 5627 11 aluminum aluminum NN cord-022526-j9kg00qf 5627 12 Equine equine JJ cord-022526-j9kg00qf 5627 13 granulomatous granulomatous JJ cord-022526-j9kg00qf 5627 14 enteritis enteritis NN cord-022526-j9kg00qf 5627 15 linked link VBN cord-022526-j9kg00qf 5627 16 with with IN cord-022526-j9kg00qf 5627 17 aluminum aluminum NN cord-022526-j9kg00qf 5627 18 Chronic chronic NN cord-022526-j9kg00qf 5627 19 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5627 20 gastroenteritis gastroenteritis NN cord-022526-j9kg00qf 5627 21 in in IN cord-022526-j9kg00qf 5627 22 the the DT cord-022526-j9kg00qf 5627 23 horse horse NN cord-022526-j9kg00qf 5627 24 Chronic Chronic NNP cord-022526-j9kg00qf 5627 25 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5627 26 dermatitis dermatitis NN cord-022526-j9kg00qf 5627 27 : : : cord-022526-j9kg00qf 5627 28 a a DT cord-022526-j9kg00qf 5627 29 manifestion manifestion NN cord-022526-j9kg00qf 5627 30 of of IN cord-022526-j9kg00qf 5627 31 a a DT cord-022526-j9kg00qf 5627 32 multisystemic multisystemic NN cord-022526-j9kg00qf 5627 33 , , , cord-022526-j9kg00qf 5627 34 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5627 35 , , , cord-022526-j9kg00qf 5627 36 epitheliotropic epitheliotropic JJ cord-022526-j9kg00qf 5627 37 disease disease NN cord-022526-j9kg00qf 5627 38 in in IN cord-022526-j9kg00qf 5627 39 five five CD cord-022526-j9kg00qf 5627 40 horses horse NNS cord-022526-j9kg00qf 5628 1 Basophilic Basophilic NNP cord-022526-j9kg00qf 5628 2 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5628 3 in in IN cord-022526-j9kg00qf 5628 4 a a DT cord-022526-j9kg00qf 5628 5 horse horse NN cord-022526-j9kg00qf 5628 6 Segmental segmental VB cord-022526-j9kg00qf 5628 7 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5628 8 colitis colitis NN cord-022526-j9kg00qf 5628 9 : : : cord-022526-j9kg00qf 5628 10 a a DT cord-022526-j9kg00qf 5628 11 review review NN cord-022526-j9kg00qf 5628 12 of of IN cord-022526-j9kg00qf 5628 13 22 22 CD cord-022526-j9kg00qf 5628 14 cases case NNS cord-022526-j9kg00qf 5628 15 Inflammatory inflammatory JJ cord-022526-j9kg00qf 5628 16 bowel bowel NN cord-022526-j9kg00qf 5628 17 disease disease NN cord-022526-j9kg00qf 5628 18 in in IN cord-022526-j9kg00qf 5628 19 horses horse NNS cord-022526-j9kg00qf 5628 20 : : : cord-022526-j9kg00qf 5628 21 11 11 CD cord-022526-j9kg00qf 5628 22 cases case NNS cord-022526-j9kg00qf 5629 1 Equine equine JJ cord-022526-j9kg00qf 5629 2 lymphocyticplasmacytic lymphocyticplasmacytic JJ cord-022526-j9kg00qf 5629 3 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5629 4 : : : cord-022526-j9kg00qf 5629 5 a a DT cord-022526-j9kg00qf 5629 6 retrospective retrospective JJ cord-022526-j9kg00qf 5629 7 study study NN cord-022526-j9kg00qf 5629 8 of of IN cord-022526-j9kg00qf 5629 9 14 14 CD cord-022526-j9kg00qf 5629 10 cases case NNS cord-022526-j9kg00qf 5629 11 12 12 CD cord-022526-j9kg00qf 5629 12 Proliferative Proliferative NNP cord-022526-j9kg00qf 5629 13 and and CC cord-022526-j9kg00qf 5629 14 Inflammatory inflammatory JJ cord-022526-j9kg00qf 5629 15 Intestinal intestinal JJ cord-022526-j9kg00qf 5629 16 Diseases disease NNS cord-022526-j9kg00qf 5630 1 Associated associate VBN cord-022526-j9kg00qf 5630 2 With with IN cord-022526-j9kg00qf 5630 3 Malabsorption malabsorption NN cord-022526-j9kg00qf 5630 4 and and CC cord-022526-j9kg00qf 5630 5 Maldigestion Maldigestion NNP cord-022526-j9kg00qf 5630 6 REFERENCES reference NNS cord-022526-j9kg00qf 5630 7 1 1 CD cord-022526-j9kg00qf 5630 8 . . . cord-022526-j9kg00qf 5631 1 Smith Smith NNP cord-022526-j9kg00qf 5631 2 BP BP NNP cord-022526-j9kg00qf 5631 3 : : : cord-022526-j9kg00qf 5632 1 Salmonella salmonella NN cord-022526-j9kg00qf 5632 2 infection infection NN cord-022526-j9kg00qf 5632 3 in in IN cord-022526-j9kg00qf 5632 4 horses horse NNS cord-022526-j9kg00qf 5632 5 Prevalence prevalence NN cord-022526-j9kg00qf 5632 6 and and CC cord-022526-j9kg00qf 5632 7 epizootiology epizootiology NN cord-022526-j9kg00qf 5632 8 of of IN cord-022526-j9kg00qf 5632 9 equine equine JJ cord-022526-j9kg00qf 5632 10 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5632 11 Emergence emergence NN cord-022526-j9kg00qf 5632 12 of of IN cord-022526-j9kg00qf 5632 13 antibiotic antibiotic JJ cord-022526-j9kg00qf 5632 14 - - HYPH cord-022526-j9kg00qf 5632 15 resistant resistant JJ cord-022526-j9kg00qf 5632 16 Salmonella Salmonella NNP cord-022526-j9kg00qf 5632 17 agona agona NN cord-022526-j9kg00qf 5632 18 in in IN cord-022526-j9kg00qf 5632 19 horses horse NNS cord-022526-j9kg00qf 5632 20 in in IN cord-022526-j9kg00qf 5632 21 Kentucky Kentucky NNP cord-022526-j9kg00qf 5632 22 Fecal Fecal NNP cord-022526-j9kg00qf 5632 23 shedding shedding NN cord-022526-j9kg00qf 5632 24 of of IN cord-022526-j9kg00qf 5632 25 Salmonella Salmonella NNP cord-022526-j9kg00qf 5632 26 spp spp NNS cord-022526-j9kg00qf 5632 27 by by IN cord-022526-j9kg00qf 5632 28 horses horse NNS cord-022526-j9kg00qf 5632 29 in in IN cord-022526-j9kg00qf 5632 30 the the DT cord-022526-j9kg00qf 5632 31 United United NNP cord-022526-j9kg00qf 5632 32 States States NNP cord-022526-j9kg00qf 5632 33 during during IN cord-022526-j9kg00qf 5632 34 1998 1998 CD cord-022526-j9kg00qf 5632 35 and and CC cord-022526-j9kg00qf 5632 36 1999 1999 CD cord-022526-j9kg00qf 5632 37 and and CC cord-022526-j9kg00qf 5632 38 detection detection NN cord-022526-j9kg00qf 5632 39 of of IN cord-022526-j9kg00qf 5632 40 Salmonella Salmonella NNP cord-022526-j9kg00qf 5632 41 spp spp NNS cord-022526-j9kg00qf 5632 42 in in IN cord-022526-j9kg00qf 5632 43 grain grain NN cord-022526-j9kg00qf 5632 44 and and CC cord-022526-j9kg00qf 5632 45 concentrate concentrate VB cord-022526-j9kg00qf 5632 46 sources source NNS cord-022526-j9kg00qf 5632 47 on on IN cord-022526-j9kg00qf 5632 48 equine equine JJ cord-022526-j9kg00qf 5632 49 operations operation NNS cord-022526-j9kg00qf 5632 50 Epidemiologic Epidemiologic NNP cord-022526-j9kg00qf 5632 51 study study NN cord-022526-j9kg00qf 5632 52 of of IN cord-022526-j9kg00qf 5632 53 salmonellae salmonellae NNP cord-022526-j9kg00qf 5632 54 shedding shed VBG cord-022526-j9kg00qf 5632 55 in in IN cord-022526-j9kg00qf 5632 56 the the DT cord-022526-j9kg00qf 5632 57 feces fece NNS cord-022526-j9kg00qf 5632 58 of of IN cord-022526-j9kg00qf 5632 59 horses horse NNS cord-022526-j9kg00qf 5632 60 and and CC cord-022526-j9kg00qf 5632 61 potential potential JJ cord-022526-j9kg00qf 5632 62 risk risk NN cord-022526-j9kg00qf 5632 63 factors factor NNS cord-022526-j9kg00qf 5632 64 for for IN cord-022526-j9kg00qf 5632 65 development development NN cord-022526-j9kg00qf 5632 66 of of IN cord-022526-j9kg00qf 5632 67 the the DT cord-022526-j9kg00qf 5632 68 infection infection NN cord-022526-j9kg00qf 5632 69 in in IN cord-022526-j9kg00qf 5632 70 hospitalized hospitalize VBN cord-022526-j9kg00qf 5632 71 horses horse NNS cord-022526-j9kg00qf 5632 72 Risk risk NN cord-022526-j9kg00qf 5632 73 factors factor NNS cord-022526-j9kg00qf 5632 74 for for IN cord-022526-j9kg00qf 5632 75 nosocomial nosocomial JJ cord-022526-j9kg00qf 5632 76 Salmonella Salmonella NNP cord-022526-j9kg00qf 5632 77 infection infection NN cord-022526-j9kg00qf 5632 78 among among IN cord-022526-j9kg00qf 5632 79 hospitalized hospitalize VBN cord-022526-j9kg00qf 5632 80 horses horse NNS cord-022526-j9kg00qf 5633 1 An an DT cord-022526-j9kg00qf 5633 2 outbreak outbreak NN cord-022526-j9kg00qf 5633 3 of of IN cord-022526-j9kg00qf 5633 4 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5633 5 among among IN cord-022526-j9kg00qf 5633 6 horses horse NNS cord-022526-j9kg00qf 5633 7 at at IN cord-022526-j9kg00qf 5633 8 a a DT cord-022526-j9kg00qf 5633 9 veterinary veterinary JJ cord-022526-j9kg00qf 5633 10 teaching teaching NN cord-022526-j9kg00qf 5633 11 hospital hospital NN cord-022526-j9kg00qf 5633 12 Outbreak outbreak NN cord-022526-j9kg00qf 5633 13 of of IN cord-022526-j9kg00qf 5633 14 Salmonella Salmonella NNP cord-022526-j9kg00qf 5633 15 infantis infantis NN cord-022526-j9kg00qf 5633 16 infection infection NN cord-022526-j9kg00qf 5633 17 in in IN cord-022526-j9kg00qf 5633 18 a a DT cord-022526-j9kg00qf 5633 19 large large JJ cord-022526-j9kg00qf 5633 20 animal animal NN cord-022526-j9kg00qf 5633 21 veterinary veterinary JJ cord-022526-j9kg00qf 5633 22 teaching teaching NN cord-022526-j9kg00qf 5633 23 hospital hospital NN cord-022526-j9kg00qf 5633 24 Influence influence NN cord-022526-j9kg00qf 5633 25 of of IN cord-022526-j9kg00qf 5633 26 fecal fecal JJ cord-022526-j9kg00qf 5633 27 shedding shedding NN cord-022526-j9kg00qf 5633 28 of of IN cord-022526-j9kg00qf 5633 29 Salmonella Salmonella NNP cord-022526-j9kg00qf 5633 30 organisms organism NNS cord-022526-j9kg00qf 5633 31 on on IN cord-022526-j9kg00qf 5633 32 mortality mortality NN cord-022526-j9kg00qf 5633 33 in in IN cord-022526-j9kg00qf 5633 34 hospitalized hospitalize VBN cord-022526-j9kg00qf 5633 35 horses horse NNS cord-022526-j9kg00qf 5633 36 Control Control NNP cord-022526-j9kg00qf 5633 37 of of IN cord-022526-j9kg00qf 5633 38 an an DT cord-022526-j9kg00qf 5633 39 outbreak outbreak NN cord-022526-j9kg00qf 5633 40 of of IN cord-022526-j9kg00qf 5633 41 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5633 42 caused cause VBN cord-022526-j9kg00qf 5633 43 by by IN cord-022526-j9kg00qf 5633 44 drug drug NN cord-022526-j9kg00qf 5633 45 - - HYPH cord-022526-j9kg00qf 5633 46 resistant resistant JJ cord-022526-j9kg00qf 5633 47 Salmonella Salmonella NNP cord-022526-j9kg00qf 5633 48 anatum anatum RB cord-022526-j9kg00qf 5633 49 in in IN cord-022526-j9kg00qf 5633 50 horses horse NNS cord-022526-j9kg00qf 5633 51 at at IN cord-022526-j9kg00qf 5633 52 a a DT cord-022526-j9kg00qf 5633 53 veterinary veterinary JJ cord-022526-j9kg00qf 5633 54 hospital hospital NN cord-022526-j9kg00qf 5633 55 and and CC cord-022526-j9kg00qf 5633 56 measures measure NNS cord-022526-j9kg00qf 5633 57 to to TO cord-022526-j9kg00qf 5633 58 prevent prevent VB cord-022526-j9kg00qf 5633 59 future future JJ cord-022526-j9kg00qf 5633 60 infections infection NNS cord-022526-j9kg00qf 5634 1 Antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5634 2 resistance resistance NN cord-022526-j9kg00qf 5634 3 in in IN cord-022526-j9kg00qf 5634 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 5634 5 and and CC cord-022526-j9kg00qf 5634 6 Escherichia Escherichia NNP cord-022526-j9kg00qf 5634 7 coli coli NNS cord-022526-j9kg00qf 5634 8 isolated isolate VBN cord-022526-j9kg00qf 5634 9 from from IN cord-022526-j9kg00qf 5634 10 horses horse NNS cord-022526-j9kg00qf 5634 11 Utilization utilization NN cord-022526-j9kg00qf 5634 12 of of IN cord-022526-j9kg00qf 5634 13 both both DT cord-022526-j9kg00qf 5634 14 phenotypic phenotypic JJ cord-022526-j9kg00qf 5634 15 and and CC cord-022526-j9kg00qf 5634 16 molecular molecular JJ cord-022526-j9kg00qf 5634 17 analyses analysis NNS cord-022526-j9kg00qf 5634 18 to to TO cord-022526-j9kg00qf 5634 19 investigate investigate VB cord-022526-j9kg00qf 5634 20 an an DT cord-022526-j9kg00qf 5634 21 outbreak outbreak NN cord-022526-j9kg00qf 5634 22 of of IN cord-022526-j9kg00qf 5634 23 multidrugresistant multidrugresistant NNP cord-022526-j9kg00qf 5634 24 Salmonella Salmonella NNP cord-022526-j9kg00qf 5634 25 anatum anatum RB cord-022526-j9kg00qf 5634 26 in in IN cord-022526-j9kg00qf 5634 27 horses horse NNS cord-022526-j9kg00qf 5634 28 Understanding understand VBG cord-022526-j9kg00qf 5634 29 the the DT cord-022526-j9kg00qf 5634 30 role role NN cord-022526-j9kg00qf 5634 31 of of IN cord-022526-j9kg00qf 5634 32 endotoxins endotoxin NNS cord-022526-j9kg00qf 5634 33 in in IN cord-022526-j9kg00qf 5634 34 gramnegative gramnegative NN cord-022526-j9kg00qf 5634 35 sepsis sepsis NN cord-022526-j9kg00qf 5634 36 Salmonellosis salmonellosis NN cord-022526-j9kg00qf 5634 37 in in IN cord-022526-j9kg00qf 5634 38 hospitalized hospitalize VBN cord-022526-j9kg00qf 5634 39 horses horse NNS cord-022526-j9kg00qf 5634 40 : : : cord-022526-j9kg00qf 5635 1 seasonality seasonality NN cord-022526-j9kg00qf 5635 2 and and CC cord-022526-j9kg00qf 5635 3 case case NN cord-022526-j9kg00qf 5635 4 fatality fatality NN cord-022526-j9kg00qf 5635 5 rates rate NNS cord-022526-j9kg00qf 5636 1 Salmonellosis salmonellosis NN cord-022526-j9kg00qf 5636 2 in in IN cord-022526-j9kg00qf 5636 3 Equidae Equidae NNP cord-022526-j9kg00qf 5636 4 : : : cord-022526-j9kg00qf 5636 5 a a DT cord-022526-j9kg00qf 5636 6 study study NN cord-022526-j9kg00qf 5636 7 of of IN cord-022526-j9kg00qf 5636 8 23 23 CD cord-022526-j9kg00qf 5636 9 cases case NNS cord-022526-j9kg00qf 5636 10 Pathogenesis Pathogenesis NNP cord-022526-j9kg00qf 5636 11 of of IN cord-022526-j9kg00qf 5636 12 acute acute JJ cord-022526-j9kg00qf 5636 13 bacterial bacterial JJ cord-022526-j9kg00qf 5636 14 diarrheal diarrheal JJ cord-022526-j9kg00qf 5636 15 disorders disorder NNS cord-022526-j9kg00qf 5637 1 The the DT cord-022526-j9kg00qf 5637 2 alimentary alimentary JJ cord-022526-j9kg00qf 5637 3 canal canal NN cord-022526-j9kg00qf 5637 4 as as IN cord-022526-j9kg00qf 5637 5 a a DT cord-022526-j9kg00qf 5637 6 microbial microbial JJ cord-022526-j9kg00qf 5637 7 habitat habitat NN cord-022526-j9kg00qf 5637 8 Enteric enteric JJ cord-022526-j9kg00qf 5637 9 defensins defensin NNS cord-022526-j9kg00qf 5637 10 : : : cord-022526-j9kg00qf 5637 11 antibiotic antibiotic JJ cord-022526-j9kg00qf 5637 12 peptide peptide NN cord-022526-j9kg00qf 5637 13 components component NNS cord-022526-j9kg00qf 5637 14 of of IN cord-022526-j9kg00qf 5637 15 intestinal intestinal JJ cord-022526-j9kg00qf 5637 16 host host NN cord-022526-j9kg00qf 5637 17 defense defense NN cord-022526-j9kg00qf 5637 18 Regional regional JJ cord-022526-j9kg00qf 5637 19 specialization specialization NN cord-022526-j9kg00qf 5637 20 in in IN cord-022526-j9kg00qf 5637 21 the the DT cord-022526-j9kg00qf 5637 22 mucosal mucosal JJ cord-022526-j9kg00qf 5637 23 immune immune JJ cord-022526-j9kg00qf 5637 24 system system NN cord-022526-j9kg00qf 5638 1 : : : cord-022526-j9kg00qf 5638 2 what what WP cord-022526-j9kg00qf 5638 3 happens happen VBZ cord-022526-j9kg00qf 5638 4 in in IN cord-022526-j9kg00qf 5638 5 the the DT cord-022526-j9kg00qf 5638 6 microcompartments microcompartment NNS cord-022526-j9kg00qf 5638 7 ? ? . cord-022526-j9kg00qf 5639 1 Salmonella salmonella NN cord-022526-j9kg00qf 5639 2 : : : cord-022526-j9kg00qf 5639 3 a a DT cord-022526-j9kg00qf 5639 4 model model NN cord-022526-j9kg00qf 5639 5 for for IN cord-022526-j9kg00qf 5639 6 bacterial bacterial JJ cord-022526-j9kg00qf 5639 7 pathogenesis pathogenesis NN cord-022526-j9kg00qf 5639 8 Pathogenesis pathogenesis NN cord-022526-j9kg00qf 5639 9 of of IN cord-022526-j9kg00qf 5639 10 bacterial bacterial JJ cord-022526-j9kg00qf 5639 11 infections infection NNS cord-022526-j9kg00qf 5639 12 in in IN cord-022526-j9kg00qf 5639 13 animals animal NNS cord-022526-j9kg00qf 5639 14 Review Review NNP cord-022526-j9kg00qf 5639 15 of of IN cord-022526-j9kg00qf 5639 16 veterinary veterinary JJ cord-022526-j9kg00qf 5639 17 microbiology microbiology NN cord-022526-j9kg00qf 5640 1 A a DT cord-022526-j9kg00qf 5640 2 preliminary preliminary JJ cord-022526-j9kg00qf 5640 3 evaluation evaluation NN cord-022526-j9kg00qf 5640 4 of of IN cord-022526-j9kg00qf 5640 5 some some DT cord-022526-j9kg00qf 5640 6 preparations preparation NNS cord-022526-j9kg00qf 5640 7 of of IN cord-022526-j9kg00qf 5640 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 5640 9 typhimurium typhimurium NN cord-022526-j9kg00qf 5640 10 vaccines vaccine NNS cord-022526-j9kg00qf 5640 11 in in IN cord-022526-j9kg00qf 5640 12 horses horse NNS cord-022526-j9kg00qf 5640 13 Aromatic aromatic JJ cord-022526-j9kg00qf 5640 14 - - HYPH cord-022526-j9kg00qf 5640 15 dependent dependent JJ cord-022526-j9kg00qf 5640 16 Salmonella Salmonella NNP cord-022526-j9kg00qf 5640 17 typhimurium typhimurium NN cord-022526-j9kg00qf 5640 18 as as IN cord-022526-j9kg00qf 5640 19 modified modify VBN cord-022526-j9kg00qf 5640 20 live live JJ cord-022526-j9kg00qf 5640 21 vaccines vaccine NNS cord-022526-j9kg00qf 5640 22 for for IN cord-022526-j9kg00qf 5640 23 calves calf NNS cord-022526-j9kg00qf 5641 1 Intranasal intranasal JJ cord-022526-j9kg00qf 5641 2 immunogenicity immunogenicity NN cord-022526-j9kg00qf 5641 3 of of IN cord-022526-j9kg00qf 5641 4 a a DT cord-022526-j9kg00qf 5641 5 Delta delta NN cord-022526-j9kg00qf 5642 1 cya cya NNP cord-022526-j9kg00qf 5642 2 Delta Delta NNP cord-022526-j9kg00qf 5642 3 crp crp NNP cord-022526-j9kg00qf 5642 4 - - HYPH cord-022526-j9kg00qf 5642 5 pabA pabA NNP cord-022526-j9kg00qf 5642 6 mutant mutant NN cord-022526-j9kg00qf 5642 7 of of IN cord-022526-j9kg00qf 5642 8 Salmonella Salmonella NNP cord-022526-j9kg00qf 5642 9 enterica enterica NN cord-022526-j9kg00qf 5642 10 serotype serotype NN cord-022526-j9kg00qf 5642 11 Typhimurium Typhimurium NNP cord-022526-j9kg00qf 5642 12 for for IN cord-022526-j9kg00qf 5642 13 the the DT cord-022526-j9kg00qf 5642 14 horse horse NN cord-022526-j9kg00qf 5642 15 M m CD cord-022526-j9kg00qf 5642 16 cells cell NNS cord-022526-j9kg00qf 5642 17 as as IN cord-022526-j9kg00qf 5642 18 ports port NNS cord-022526-j9kg00qf 5642 19 of of IN cord-022526-j9kg00qf 5642 20 entry entry NN cord-022526-j9kg00qf 5642 21 for for IN cord-022526-j9kg00qf 5642 22 enteroinvasive enteroinvasive JJ cord-022526-j9kg00qf 5642 23 pathogens pathogen NNS cord-022526-j9kg00qf 5642 24 : : : cord-022526-j9kg00qf 5642 25 mechanisms mechanism NNS cord-022526-j9kg00qf 5642 26 of of IN cord-022526-j9kg00qf 5642 27 interaction interaction NN cord-022526-j9kg00qf 5642 28 , , , cord-022526-j9kg00qf 5642 29 consequences consequence NNS cord-022526-j9kg00qf 5642 30 for for IN cord-022526-j9kg00qf 5642 31 the the DT cord-022526-j9kg00qf 5642 32 disease disease NN cord-022526-j9kg00qf 5642 33 process process NN cord-022526-j9kg00qf 5642 34 Type Type NNP cord-022526-j9kg00qf 5642 35 III III NNP cord-022526-j9kg00qf 5642 36 secretion secretion NN cord-022526-j9kg00qf 5642 37 machines machine NNS cord-022526-j9kg00qf 5642 38 : : : cord-022526-j9kg00qf 5642 39 bacterial bacterial JJ cord-022526-j9kg00qf 5642 40 devices device NNS cord-022526-j9kg00qf 5642 41 for for IN cord-022526-j9kg00qf 5642 42 protein protein NN cord-022526-j9kg00qf 5642 43 delivery delivery NN cord-022526-j9kg00qf 5642 44 into into IN cord-022526-j9kg00qf 5642 45 host host NN cord-022526-j9kg00qf 5642 46 cells cell NNS cord-022526-j9kg00qf 5642 47 Epithelial epithelial JJ cord-022526-j9kg00qf 5642 48 cells cell NNS cord-022526-j9kg00qf 5642 49 as as IN cord-022526-j9kg00qf 5642 50 sensors sensor NNS cord-022526-j9kg00qf 5642 51 for for IN cord-022526-j9kg00qf 5642 52 microbial microbial JJ cord-022526-j9kg00qf 5642 53 infection infection NN cord-022526-j9kg00qf 5643 1 Extraintestinal extraintestinal JJ cord-022526-j9kg00qf 5643 2 dissemination dissemination NN cord-022526-j9kg00qf 5643 3 of of IN cord-022526-j9kg00qf 5643 4 Salmonella Salmonella NNP cord-022526-j9kg00qf 5643 5 by by IN cord-022526-j9kg00qf 5643 6 CD18-expressing cd18-expresse VBG cord-022526-j9kg00qf 5643 7 phagocytes phagocyte NNS cord-022526-j9kg00qf 5643 8 Oxygen oxygen NN cord-022526-j9kg00qf 5643 9 - - HYPH cord-022526-j9kg00qf 5643 10 dependent dependent JJ cord-022526-j9kg00qf 5643 11 anti anti JJ cord-022526-j9kg00qf 5643 12 - - JJ cord-022526-j9kg00qf 5643 13 Salmonella salmonella JJ cord-022526-j9kg00qf 5643 14 activity activity NN cord-022526-j9kg00qf 5643 15 of of IN cord-022526-j9kg00qf 5643 16 macrophages macrophage NNS cord-022526-j9kg00qf 5643 17 Pathogenesis Pathogenesis NNP cord-022526-j9kg00qf 5643 18 of of IN cord-022526-j9kg00qf 5643 19 experimental experimental JJ cord-022526-j9kg00qf 5643 20 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5643 21 : : : cord-022526-j9kg00qf 5643 22 inhibition inhibition NN cord-022526-j9kg00qf 5643 23 of of IN cord-022526-j9kg00qf 5643 24 protein protein NN cord-022526-j9kg00qf 5643 25 synthesis synthesis NN cord-022526-j9kg00qf 5643 26 by by IN cord-022526-j9kg00qf 5643 27 cytotoxin cytotoxin NNP cord-022526-j9kg00qf 5643 28 Pathogenesis Pathogenesis NNP cord-022526-j9kg00qf 5643 29 of of IN cord-022526-j9kg00qf 5643 30 Salmonella Salmonella NNP cord-022526-j9kg00qf 5643 31 - - HYPH cord-022526-j9kg00qf 5643 32 mediated mediate VBN cord-022526-j9kg00qf 5643 33 intestinal intestinal JJ cord-022526-j9kg00qf 5643 34 fluid fluid JJ cord-022526-j9kg00qf 5643 35 secretion secretion NN cord-022526-j9kg00qf 5643 36 : : : cord-022526-j9kg00qf 5643 37 activation activation NN cord-022526-j9kg00qf 5643 38 of of IN cord-022526-j9kg00qf 5643 39 adenylate adenylate NN cord-022526-j9kg00qf 5643 40 cyclase cyclase NN cord-022526-j9kg00qf 5643 41 and and CC cord-022526-j9kg00qf 5643 42 inhibition inhibition NN cord-022526-j9kg00qf 5643 43 by by IN cord-022526-j9kg00qf 5643 44 indomethacin indomethacin JJ cord-022526-j9kg00qf 5643 45 Elevated elevated JJ cord-022526-j9kg00qf 5643 46 cAMP camp NN cord-022526-j9kg00qf 5643 47 in in IN cord-022526-j9kg00qf 5643 48 intestinal intestinal JJ cord-022526-j9kg00qf 5643 49 epithelial epithelial JJ cord-022526-j9kg00qf 5643 50 cells cell NNS cord-022526-j9kg00qf 5643 51 during during IN cord-022526-j9kg00qf 5643 52 experimental experimental JJ cord-022526-j9kg00qf 5643 53 cholera cholera NN cord-022526-j9kg00qf 5643 54 and and CC cord-022526-j9kg00qf 5643 55 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5643 56 Role role NN cord-022526-j9kg00qf 5643 57 of of IN cord-022526-j9kg00qf 5643 58 Salmonella Salmonella NNP cord-022526-j9kg00qf 5643 59 enterotoxin enterotoxin NN cord-022526-j9kg00qf 5643 60 in in IN cord-022526-j9kg00qf 5643 61 overall overall JJ cord-022526-j9kg00qf 5643 62 virulence virulence NN cord-022526-j9kg00qf 5643 63 of of IN cord-022526-j9kg00qf 5643 64 the the DT cord-022526-j9kg00qf 5643 65 organism organism NN cord-022526-j9kg00qf 5643 66 Mutation Mutation NNP cord-022526-j9kg00qf 5643 67 of of IN cord-022526-j9kg00qf 5643 68 invH invH NNS cord-022526-j9kg00qf 5643 69 , , , cord-022526-j9kg00qf 5643 70 but but CC cord-022526-j9kg00qf 5643 71 not not RB cord-022526-j9kg00qf 5643 72 stn stn NNP cord-022526-j9kg00qf 5643 73 , , , cord-022526-j9kg00qf 5643 74 reduces reduce VBZ cord-022526-j9kg00qf 5643 75 Salmonella salmonella NN cord-022526-j9kg00qf 5643 76 - - HYPH cord-022526-j9kg00qf 5643 77 induced induce VBN cord-022526-j9kg00qf 5643 78 enteritis enteritis NN cord-022526-j9kg00qf 5643 79 in in IN cord-022526-j9kg00qf 5643 80 cattle cattle NNS cord-022526-j9kg00qf 5643 81 Importance importance NN cord-022526-j9kg00qf 5643 82 of of IN cord-022526-j9kg00qf 5643 83 the the DT cord-022526-j9kg00qf 5643 84 intestinal intestinal JJ cord-022526-j9kg00qf 5643 85 inflammatory inflammatory JJ cord-022526-j9kg00qf 5643 86 reaction reaction NN cord-022526-j9kg00qf 5643 87 in in IN cord-022526-j9kg00qf 5643 88 salmonella salmonella NN cord-022526-j9kg00qf 5643 89 - - HYPH cord-022526-j9kg00qf 5643 90 mediated mediate VBN cord-022526-j9kg00qf 5643 91 intestinal intestinal JJ cord-022526-j9kg00qf 5643 92 secretion secretion NN cord-022526-j9kg00qf 5643 93 Pathophysiology pathophysiology NN cord-022526-j9kg00qf 5643 94 of of IN cord-022526-j9kg00qf 5643 95 infectious infectious JJ cord-022526-j9kg00qf 5643 96 diarrhea diarrhea NN cord-022526-j9kg00qf 5643 97 : : : cord-022526-j9kg00qf 5643 98 changes change NNS cord-022526-j9kg00qf 5643 99 in in IN cord-022526-j9kg00qf 5643 100 intestinal intestinal JJ cord-022526-j9kg00qf 5643 101 structure structure NN cord-022526-j9kg00qf 5643 102 and and CC cord-022526-j9kg00qf 5643 103 function function VB cord-022526-j9kg00qf 5643 104 Digestive digestive JJ cord-022526-j9kg00qf 5643 105 physiology physiology NN cord-022526-j9kg00qf 5643 106 of of IN cord-022526-j9kg00qf 5643 107 the the DT cord-022526-j9kg00qf 5643 108 large large JJ cord-022526-j9kg00qf 5643 109 intestine intestine NN cord-022526-j9kg00qf 5643 110 in in IN cord-022526-j9kg00qf 5643 111 adult adult NN cord-022526-j9kg00qf 5643 112 horses horse NNS cord-022526-j9kg00qf 5643 113 . . . cord-022526-j9kg00qf 5644 1 2 2 LS cord-022526-j9kg00qf 5644 2 . . . cord-022526-j9kg00qf 5645 1 Pathophysiology pathophysiology NN cord-022526-j9kg00qf 5645 2 of of IN cord-022526-j9kg00qf 5645 3 colitis colitis NN cord-022526-j9kg00qf 5645 4 Neuroimmunophysiology neuroimmunophysiology NN cord-022526-j9kg00qf 5645 5 of of IN cord-022526-j9kg00qf 5645 6 the the DT cord-022526-j9kg00qf 5645 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5645 8 mucosa mucosa NN cord-022526-j9kg00qf 5645 9 : : : cord-022526-j9kg00qf 5645 10 implications implication NNS cord-022526-j9kg00qf 5645 11 for for IN cord-022526-j9kg00qf 5645 12 inflammatory inflammatory JJ cord-022526-j9kg00qf 5645 13 diseases disease NNS cord-022526-j9kg00qf 5646 1 Transepithelial Transepithelial NNP cord-022526-j9kg00qf 5646 2 signaling signal VBG cord-022526-j9kg00qf 5646 3 to to IN cord-022526-j9kg00qf 5646 4 neutrophils neutrophil NNS cord-022526-j9kg00qf 5646 5 by by IN cord-022526-j9kg00qf 5646 6 salmonellae salmonellae NNP cord-022526-j9kg00qf 5646 7 : : : cord-022526-j9kg00qf 5646 8 a a DT cord-022526-j9kg00qf 5646 9 novel novel JJ cord-022526-j9kg00qf 5646 10 virulence virulence NN cord-022526-j9kg00qf 5646 11 mechanism mechanism NN cord-022526-j9kg00qf 5646 12 for for IN cord-022526-j9kg00qf 5646 13 gastroenteritis gastroenteritis JJ cord-022526-j9kg00qf 5646 14 Review Review NNP cord-022526-j9kg00qf 5646 15 article article NN cord-022526-j9kg00qf 5646 16 : : : cord-022526-j9kg00qf 5646 17 pathobiology pathobiology NN cord-022526-j9kg00qf 5646 18 of of IN cord-022526-j9kg00qf 5646 19 neutrophil neutrophil NN cord-022526-j9kg00qf 5646 20 interactions interaction NNS cord-022526-j9kg00qf 5646 21 with with IN cord-022526-j9kg00qf 5646 22 intestinal intestinal JJ cord-022526-j9kg00qf 5646 23 epithelia epithelium NNS cord-022526-j9kg00qf 5646 24 Equine equine JJ cord-022526-j9kg00qf 5646 25 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5646 26 : : : cord-022526-j9kg00qf 5646 27 experimental experimental JJ cord-022526-j9kg00qf 5646 28 production production NN cord-022526-j9kg00qf 5646 29 of of IN cord-022526-j9kg00qf 5646 30 four four CD cord-022526-j9kg00qf 5646 31 syndromes syndrome NNS cord-022526-j9kg00qf 5646 32 Characteristics characteristic NNS cord-022526-j9kg00qf 5646 33 and and CC cord-022526-j9kg00qf 5646 34 risk risk NN cord-022526-j9kg00qf 5646 35 factors factor NNS cord-022526-j9kg00qf 5646 36 for for IN cord-022526-j9kg00qf 5646 37 failure failure NN cord-022526-j9kg00qf 5646 38 to to TO cord-022526-j9kg00qf 5646 39 survive survive VB cord-022526-j9kg00qf 5646 40 of of IN cord-022526-j9kg00qf 5646 41 horses horse NNS cord-022526-j9kg00qf 5646 42 with with IN cord-022526-j9kg00qf 5646 43 acute acute JJ cord-022526-j9kg00qf 5646 44 diarrhea diarrhea NN cord-022526-j9kg00qf 5646 45 : : : cord-022526-j9kg00qf 5646 46 122 122 CD cord-022526-j9kg00qf 5646 47 cases case NNS cord-022526-j9kg00qf 5646 48 ( ( -LRB- cord-022526-j9kg00qf 5646 49 1990 1990 CD cord-022526-j9kg00qf 5646 50 - - SYM cord-022526-j9kg00qf 5646 51 1996 1996 CD cord-022526-j9kg00qf 5646 52 ) ) -RRB- cord-022526-j9kg00qf 5647 1 Diagnosing diagnose VBG cord-022526-j9kg00qf 5647 2 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5647 3 in in IN cord-022526-j9kg00qf 5647 4 horses horse NNS cord-022526-j9kg00qf 5647 5 : : : cord-022526-j9kg00qf 5647 6 culturing culture VBG cord-022526-j9kg00qf 5647 7 of of IN cord-022526-j9kg00qf 5647 8 multiple multiple JJ cord-022526-j9kg00qf 5647 9 versus versus IN cord-022526-j9kg00qf 5647 10 single single JJ cord-022526-j9kg00qf 5647 11 faecal faecal JJ cord-022526-j9kg00qf 5647 12 samples sample NNS cord-022526-j9kg00qf 5647 13 Comparison comparison NN cord-022526-j9kg00qf 5647 14 of of IN cord-022526-j9kg00qf 5647 15 rectal rectal JJ cord-022526-j9kg00qf 5647 16 mucosal mucosal JJ cord-022526-j9kg00qf 5647 17 cultures culture NNS cord-022526-j9kg00qf 5647 18 and and CC cord-022526-j9kg00qf 5647 19 fecal fecal JJ cord-022526-j9kg00qf 5647 20 cultures culture NNS cord-022526-j9kg00qf 5647 21 in in IN cord-022526-j9kg00qf 5647 22 detecting detect VBG cord-022526-j9kg00qf 5647 23 Salmonella Salmonella NNP cord-022526-j9kg00qf 5647 24 infection infection NN cord-022526-j9kg00qf 5647 25 in in IN cord-022526-j9kg00qf 5647 26 horses horse NNS cord-022526-j9kg00qf 5647 27 and and CC cord-022526-j9kg00qf 5647 28 cattle cattle NNS cord-022526-j9kg00qf 5647 29 Comparison comparison NN cord-022526-j9kg00qf 5647 30 of of IN cord-022526-j9kg00qf 5647 31 polymerase polymerase NN cord-022526-j9kg00qf 5647 32 chain chain NN cord-022526-j9kg00qf 5647 33 reaction reaction NN cord-022526-j9kg00qf 5647 34 and and CC cord-022526-j9kg00qf 5647 35 microbiological microbiological JJ cord-022526-j9kg00qf 5647 36 culture culture NN cord-022526-j9kg00qf 5647 37 for for IN cord-022526-j9kg00qf 5647 38 detection detection NN cord-022526-j9kg00qf 5647 39 of of IN cord-022526-j9kg00qf 5647 40 salmonellae salmonellae NNP cord-022526-j9kg00qf 5647 41 in in IN cord-022526-j9kg00qf 5647 42 equine equine JJ cord-022526-j9kg00qf 5647 43 feces fece NNS cord-022526-j9kg00qf 5647 44 and and CC cord-022526-j9kg00qf 5647 45 environmental environmental JJ cord-022526-j9kg00qf 5647 46 samples sample NNS cord-022526-j9kg00qf 5647 47 Rapid Rapid NNP cord-022526-j9kg00qf 5647 48 PCR PCR NNP cord-022526-j9kg00qf 5647 49 detection detection NN cord-022526-j9kg00qf 5647 50 of of IN cord-022526-j9kg00qf 5647 51 Salmonella Salmonella NNP cord-022526-j9kg00qf 5647 52 in in IN cord-022526-j9kg00qf 5647 53 horse horse NN cord-022526-j9kg00qf 5647 54 faecal faecal JJ cord-022526-j9kg00qf 5647 55 samples sample NNS cord-022526-j9kg00qf 5648 1 Potomac Potomac NNP cord-022526-j9kg00qf 5648 2 horse horse NN cord-022526-j9kg00qf 5648 3 fever fever NN cord-022526-j9kg00qf 5649 1 Equine equine JJ cord-022526-j9kg00qf 5649 2 monocytic monocytic JJ cord-022526-j9kg00qf 5649 3 ehrlichiosis ehrlichiosis NN cord-022526-j9kg00qf 5649 4 ( ( -LRB- cord-022526-j9kg00qf 5649 5 Potomac Potomac NNP cord-022526-j9kg00qf 5649 6 horse horse NN cord-022526-j9kg00qf 5649 7 fever fever NN cord-022526-j9kg00qf 5649 8 ) ) -RRB- cord-022526-j9kg00qf 5649 9 : : : cord-022526-j9kg00qf 5650 1 a a DT cord-022526-j9kg00qf 5650 2 review review NN cord-022526-j9kg00qf 5650 3 Experimental experimental JJ cord-022526-j9kg00qf 5650 4 reproduction reproduction NN cord-022526-j9kg00qf 5650 5 of of IN cord-022526-j9kg00qf 5650 6 Potomac Potomac NNP cord-022526-j9kg00qf 5650 7 horse horse NN cord-022526-j9kg00qf 5650 8 fever fever NN cord-022526-j9kg00qf 5650 9 in in IN cord-022526-j9kg00qf 5650 10 horses horse NNS cord-022526-j9kg00qf 5650 11 with with IN cord-022526-j9kg00qf 5650 12 a a DT cord-022526-j9kg00qf 5650 13 newly newly RB cord-022526-j9kg00qf 5650 14 isolated isolate VBN cord-022526-j9kg00qf 5650 15 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5650 16 organism organism NN cord-022526-j9kg00qf 5650 17 Causative causative JJ cord-022526-j9kg00qf 5650 18 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5650 19 organisms organism NNS cord-022526-j9kg00qf 5650 20 in in IN cord-022526-j9kg00qf 5650 21 Potomac Potomac NNP cord-022526-j9kg00qf 5650 22 horse horse NN cord-022526-j9kg00qf 5650 23 fever fever NN cord-022526-j9kg00qf 5651 1 Ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5651 2 diseases disease NNS cord-022526-j9kg00qf 5651 3 Attempted attempt VBD cord-022526-j9kg00qf 5651 4 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5651 5 risticii risticii NN cord-022526-j9kg00qf 5651 6 transmission transmission NN cord-022526-j9kg00qf 5651 7 with with IN cord-022526-j9kg00qf 5651 8 Dermacentor Dermacentor NNP cord-022526-j9kg00qf 5651 9 variabilis variabilis NNP cord-022526-j9kg00qf 5651 10 ( ( -LRB- cord-022526-j9kg00qf 5652 1 Acari Acari NNP cord-022526-j9kg00qf 5652 2 : : : cord-022526-j9kg00qf 5652 3 Ixodidae Ixodidae NNP cord-022526-j9kg00qf 5652 4 ) ) -RRB- cord-022526-j9kg00qf 5653 1 Attempted attempt VBN cord-022526-j9kg00qf 5653 2 transmission transmission NN cord-022526-j9kg00qf 5653 3 of of IN cord-022526-j9kg00qf 5653 4 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5653 5 risticii risticii NN cord-022526-j9kg00qf 5653 6 ( ( -LRB- cord-022526-j9kg00qf 5653 7 Rickettsiaceae Rickettsiaceae NNP cord-022526-j9kg00qf 5653 8 ) ) -RRB- cord-022526-j9kg00qf 5653 9 with with IN cord-022526-j9kg00qf 5653 10 Stomoxys Stomoxys NNP cord-022526-j9kg00qf 5653 11 calcitrans calcitran NNS cord-022526-j9kg00qf 5653 12 ( ( -LRB- cord-022526-j9kg00qf 5653 13 Diptera Diptera NNP cord-022526-j9kg00qf 5653 14 : : : cord-022526-j9kg00qf 5653 15 Muscidae Muscidae NNP cord-022526-j9kg00qf 5653 16 ) ) -RRB- cord-022526-j9kg00qf 5653 17 Production production NN cord-022526-j9kg00qf 5653 18 and and CC cord-022526-j9kg00qf 5653 19 characterization characterization NN cord-022526-j9kg00qf 5653 20 of of IN cord-022526-j9kg00qf 5653 21 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5653 22 risticii risticii NN cord-022526-j9kg00qf 5653 23 , , , cord-022526-j9kg00qf 5653 24 the the DT cord-022526-j9kg00qf 5653 25 agent agent NN cord-022526-j9kg00qf 5653 26 of of IN cord-022526-j9kg00qf 5653 27 Potomac Potomac NNP cord-022526-j9kg00qf 5653 28 horse horse NN cord-022526-j9kg00qf 5653 29 fever fever NN cord-022526-j9kg00qf 5653 30 , , , cord-022526-j9kg00qf 5653 31 from from IN cord-022526-j9kg00qf 5653 32 snails snail NNS cord-022526-j9kg00qf 5653 33 ( ( -LRB- cord-022526-j9kg00qf 5653 34 Pleuroceridae Pleuroceridae NNP cord-022526-j9kg00qf 5653 35 : : : cord-022526-j9kg00qf 5653 36 Juga Juga NNP cord-022526-j9kg00qf 5653 37 spp spp NNS cord-022526-j9kg00qf 5653 38 . . . cord-022526-j9kg00qf 5653 39 ) ) -RRB- cord-022526-j9kg00qf 5654 1 in in IN cord-022526-j9kg00qf 5654 2 aquarium aquarium JJ cord-022526-j9kg00qf 5654 3 culture culture NN cord-022526-j9kg00qf 5654 4 and and CC cord-022526-j9kg00qf 5654 5 genetic genetic JJ cord-022526-j9kg00qf 5654 6 comparison comparison NN cord-022526-j9kg00qf 5654 7 to to IN cord-022526-j9kg00qf 5654 8 equine equine JJ cord-022526-j9kg00qf 5654 9 strains strain NNS cord-022526-j9kg00qf 5654 10 Infection infection NN cord-022526-j9kg00qf 5654 11 of of IN cord-022526-j9kg00qf 5654 12 aquatic aquatic JJ cord-022526-j9kg00qf 5654 13 insects insect NNS cord-022526-j9kg00qf 5654 14 with with IN cord-022526-j9kg00qf 5654 15 trematode trematode NN cord-022526-j9kg00qf 5654 16 metacercariae metacercariae NN cord-022526-j9kg00qf 5654 17 carrying carry VBG cord-022526-j9kg00qf 5654 18 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5654 19 risticii risticii NN cord-022526-j9kg00qf 5654 20 , , , cord-022526-j9kg00qf 5654 21 the the DT cord-022526-j9kg00qf 5654 22 cause cause NN cord-022526-j9kg00qf 5654 23 of of IN cord-022526-j9kg00qf 5654 24 Potomac Potomac NNP cord-022526-j9kg00qf 5654 25 horse horse NN cord-022526-j9kg00qf 5654 26 fever fever NN cord-022526-j9kg00qf 5654 27 Transmission transmission NN cord-022526-j9kg00qf 5654 28 of of IN cord-022526-j9kg00qf 5654 29 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5654 30 risticii risticii NN cord-022526-j9kg00qf 5654 31 , , , cord-022526-j9kg00qf 5654 32 the the DT cord-022526-j9kg00qf 5654 33 agent agent NN cord-022526-j9kg00qf 5654 34 of of IN cord-022526-j9kg00qf 5654 35 Potomac Potomac NNP cord-022526-j9kg00qf 5654 36 horse horse NN cord-022526-j9kg00qf 5654 37 fever fever NN cord-022526-j9kg00qf 5654 38 , , , cord-022526-j9kg00qf 5654 39 using use VBG cord-022526-j9kg00qf 5654 40 naturally naturally RB cord-022526-j9kg00qf 5654 41 infected infect VBN cord-022526-j9kg00qf 5654 42 aquatic aquatic JJ cord-022526-j9kg00qf 5654 43 insects insect NNS cord-022526-j9kg00qf 5654 44 and and CC cord-022526-j9kg00qf 5654 45 helminth helminth JJ cord-022526-j9kg00qf 5654 46 vectors vector NNS cord-022526-j9kg00qf 5654 47 : : : cord-022526-j9kg00qf 5654 48 preliminary preliminary JJ cord-022526-j9kg00qf 5654 49 report report NN cord-022526-j9kg00qf 5654 50 Infection infection NN cord-022526-j9kg00qf 5654 51 rate rate NN cord-022526-j9kg00qf 5654 52 of of IN cord-022526-j9kg00qf 5654 53 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5654 54 risticii risticii NN cord-022526-j9kg00qf 5654 55 , , , cord-022526-j9kg00qf 5654 56 the the DT cord-022526-j9kg00qf 5654 57 agent agent NN cord-022526-j9kg00qf 5654 58 of of IN cord-022526-j9kg00qf 5654 59 Potomac Potomac NNP cord-022526-j9kg00qf 5654 60 horse horse NN cord-022526-j9kg00qf 5654 61 fever fever NN cord-022526-j9kg00qf 5654 62 , , , cord-022526-j9kg00qf 5654 63 in in IN cord-022526-j9kg00qf 5654 64 freshwater freshwater JJ cord-022526-j9kg00qf 5654 65 stream stream NN cord-022526-j9kg00qf 5654 66 snails snail NNS cord-022526-j9kg00qf 5654 67 ( ( -LRB- cord-022526-j9kg00qf 5654 68 Juga Juga NNP cord-022526-j9kg00qf 5654 69 yrekaensis yrekaensis NN cord-022526-j9kg00qf 5654 70 ) ) -RRB- cord-022526-j9kg00qf 5654 71 from from IN cord-022526-j9kg00qf 5654 72 northern northern JJ cord-022526-j9kg00qf 5654 73 California California NNP cord-022526-j9kg00qf 5654 74 Ultrastructural Ultrastructural NNP cord-022526-j9kg00qf 5654 75 study study NN cord-022526-j9kg00qf 5654 76 of of IN cord-022526-j9kg00qf 5654 77 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5654 78 organisms organism NNS cord-022526-j9kg00qf 5654 79 in in IN cord-022526-j9kg00qf 5654 80 the the DT cord-022526-j9kg00qf 5654 81 large large JJ cord-022526-j9kg00qf 5654 82 colons colon NNS cord-022526-j9kg00qf 5654 83 of of IN cord-022526-j9kg00qf 5654 84 ponies pony NNS cord-022526-j9kg00qf 5654 85 infected infect VBN cord-022526-j9kg00qf 5654 86 with with IN cord-022526-j9kg00qf 5654 87 Potomac Potomac NNP cord-022526-j9kg00qf 5654 88 horse horse NN cord-022526-j9kg00qf 5654 89 fever fever NN cord-022526-j9kg00qf 5655 1 Enterocolitis Enterocolitis NNP cord-022526-j9kg00qf 5655 2 caused cause VBN cord-022526-j9kg00qf 5655 3 by by IN cord-022526-j9kg00qf 5655 4 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5655 5 sp sp NN cord-022526-j9kg00qf 5655 6 . . . cord-022526-j9kg00qf 5656 1 in in IN cord-022526-j9kg00qf 5656 2 the the DT cord-022526-j9kg00qf 5656 3 horse horse NN cord-022526-j9kg00qf 5656 4 ( ( -LRB- cord-022526-j9kg00qf 5656 5 Potomac Potomac NNP cord-022526-j9kg00qf 5656 6 horse horse NN cord-022526-j9kg00qf 5656 7 fever fever NN cord-022526-j9kg00qf 5656 8 ) ) -RRB- cord-022526-j9kg00qf 5656 9 Growth growth NN cord-022526-j9kg00qf 5656 10 of of IN cord-022526-j9kg00qf 5656 11 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5656 12 risticii risticii NN cord-022526-j9kg00qf 5656 13 in in IN cord-022526-j9kg00qf 5656 14 human human JJ cord-022526-j9kg00qf 5656 15 colonic colonic JJ cord-022526-j9kg00qf 5656 16 epithelial epithelial JJ cord-022526-j9kg00qf 5656 17 cells cell NNS cord-022526-j9kg00qf 5657 1 Respiratory respiratory JJ cord-022526-j9kg00qf 5657 2 burst burst NN cord-022526-j9kg00qf 5657 3 activity activity NN cord-022526-j9kg00qf 5657 4 associated associate VBN cord-022526-j9kg00qf 5657 5 with with IN cord-022526-j9kg00qf 5657 6 phagocytosis phagocytosis NN cord-022526-j9kg00qf 5657 7 of of IN cord-022526-j9kg00qf 5657 8 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5657 9 risticii risticii NN cord-022526-j9kg00qf 5657 10 by by IN cord-022526-j9kg00qf 5657 11 mouse mouse NN cord-022526-j9kg00qf 5657 12 peritoneal peritoneal JJ cord-022526-j9kg00qf 5657 13 macrophages macrophage NNS cord-022526-j9kg00qf 5658 1 In in IN cord-022526-j9kg00qf 5658 2 vitro vitro FW cord-022526-j9kg00qf 5658 3 killing killing NN cord-022526-j9kg00qf 5658 4 of of IN cord-022526-j9kg00qf 5658 5 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5658 6 risticii risticii NN cord-022526-j9kg00qf 5658 7 by by IN cord-022526-j9kg00qf 5658 8 activated activate VBN cord-022526-j9kg00qf 5658 9 and and CC cord-022526-j9kg00qf 5658 10 immune immune JJ cord-022526-j9kg00qf 5658 11 mouse mouse NN cord-022526-j9kg00qf 5658 12 peritoneal peritoneal NN cord-022526-j9kg00qf 5658 13 macrophages macrophage NNS cord-022526-j9kg00qf 5659 1 Lack lack NN cord-022526-j9kg00qf 5659 2 of of IN cord-022526-j9kg00qf 5659 3 lysosomal lysosomal JJ cord-022526-j9kg00qf 5659 4 fusion fusion NN cord-022526-j9kg00qf 5659 5 with with IN cord-022526-j9kg00qf 5659 6 phagosomes phagosome NNS cord-022526-j9kg00qf 5659 7 containing contain VBG cord-022526-j9kg00qf 5659 8 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5659 9 risticii risticii NN cord-022526-j9kg00qf 5659 10 in in IN cord-022526-j9kg00qf 5659 11 P388D1 P388D1 NNP cord-022526-j9kg00qf 5659 12 cells cell NNS cord-022526-j9kg00qf 5659 13 : : : cord-022526-j9kg00qf 5660 1 abrogation abrogation NN cord-022526-j9kg00qf 5660 2 of of IN cord-022526-j9kg00qf 5660 3 inhibition inhibition NN cord-022526-j9kg00qf 5660 4 with with IN cord-022526-j9kg00qf 5660 5 oxytetracycline oxytetracycline JJ cord-022526-j9kg00qf 5660 6 Pathophysiological Pathophysiological NNP cord-022526-j9kg00qf 5660 7 changes change VBZ cord-022526-j9kg00qf 5660 8 in in IN cord-022526-j9kg00qf 5660 9 the the DT cord-022526-j9kg00qf 5660 10 large large JJ cord-022526-j9kg00qf 5660 11 colon colon NN cord-022526-j9kg00qf 5660 12 of of IN cord-022526-j9kg00qf 5660 13 horses horse NNS cord-022526-j9kg00qf 5660 14 infected infect VBN cord-022526-j9kg00qf 5660 15 with with IN cord-022526-j9kg00qf 5660 16 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5660 17 risticii risticii NNP cord-022526-j9kg00qf 5660 18 Disease Disease NNP cord-022526-j9kg00qf 5660 19 features feature VBZ cord-022526-j9kg00qf 5660 20 in in IN cord-022526-j9kg00qf 5660 21 horses horse NNS cord-022526-j9kg00qf 5660 22 with with IN cord-022526-j9kg00qf 5660 23 induced induce VBN cord-022526-j9kg00qf 5660 24 equine equine JJ cord-022526-j9kg00qf 5660 25 monocytic monocytic JJ cord-022526-j9kg00qf 5660 26 ehrlichiosis ehrlichiosis NNP cord-022526-j9kg00qf 5660 27 ( ( -LRB- cord-022526-j9kg00qf 5660 28 Potomac Potomac NNP cord-022526-j9kg00qf 5660 29 horse horse NN cord-022526-j9kg00qf 5660 30 fever fever NN cord-022526-j9kg00qf 5660 31 ) ) -RRB- cord-022526-j9kg00qf 5661 1 Clinical clinical JJ cord-022526-j9kg00qf 5661 2 and and CC cord-022526-j9kg00qf 5661 3 hematologic hematologic JJ cord-022526-j9kg00qf 5661 4 variables variable NNS cord-022526-j9kg00qf 5661 5 in in IN cord-022526-j9kg00qf 5661 6 ponies pony NNS cord-022526-j9kg00qf 5661 7 with with IN cord-022526-j9kg00qf 5661 8 experimentally experimentally RB cord-022526-j9kg00qf 5661 9 induced induce VBN cord-022526-j9kg00qf 5661 10 equine equine JJ cord-022526-j9kg00qf 5661 11 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5661 12 colitis colitis NN cord-022526-j9kg00qf 5661 13 ( ( -LRB- cord-022526-j9kg00qf 5661 14 Potomac Potomac NNP cord-022526-j9kg00qf 5661 15 horse horse NN cord-022526-j9kg00qf 5661 16 fever fever NN cord-022526-j9kg00qf 5661 17 ) ) -RRB- cord-022526-j9kg00qf 5662 1 Evaluation evaluation NN cord-022526-j9kg00qf 5662 2 of of IN cord-022526-j9kg00qf 5662 3 fetal fetal JJ cord-022526-j9kg00qf 5662 4 infection infection NN cord-022526-j9kg00qf 5662 5 and and CC cord-022526-j9kg00qf 5662 6 abortion abortion NN cord-022526-j9kg00qf 5662 7 in in IN cord-022526-j9kg00qf 5662 8 pregnant pregnant JJ cord-022526-j9kg00qf 5662 9 ponies pony NNS cord-022526-j9kg00qf 5662 10 experimentally experimentally RB cord-022526-j9kg00qf 5662 11 infected infect VBN cord-022526-j9kg00qf 5662 12 with with IN cord-022526-j9kg00qf 5662 13 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 14 risticii risticii NN cord-022526-j9kg00qf 5662 15 Identification identification NN cord-022526-j9kg00qf 5662 16 of of IN cord-022526-j9kg00qf 5662 17 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 18 risticii risticii NNP cord-022526-j9kg00qf 5662 19 as as IN cord-022526-j9kg00qf 5662 20 the the DT cord-022526-j9kg00qf 5662 21 causative causative JJ cord-022526-j9kg00qf 5662 22 agent agent NN cord-022526-j9kg00qf 5662 23 of of IN cord-022526-j9kg00qf 5662 24 two two CD cord-022526-j9kg00qf 5662 25 equine equine JJ cord-022526-j9kg00qf 5662 26 abortions abortion NNS cord-022526-j9kg00qf 5662 27 following follow VBG cord-022526-j9kg00qf 5662 28 natural natural JJ cord-022526-j9kg00qf 5662 29 maternal maternal JJ cord-022526-j9kg00qf 5662 30 infection infection NN cord-022526-j9kg00qf 5662 31 Effect effect NN cord-022526-j9kg00qf 5662 32 of of IN cord-022526-j9kg00qf 5662 33 equine equine JJ cord-022526-j9kg00qf 5662 34 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5662 35 colitis colitis NN cord-022526-j9kg00qf 5662 36 on on IN cord-022526-j9kg00qf 5662 37 the the DT cord-022526-j9kg00qf 5662 38 hemostatic hemostatic JJ cord-022526-j9kg00qf 5662 39 system system NN cord-022526-j9kg00qf 5662 40 in in IN cord-022526-j9kg00qf 5662 41 ponies pony NNS cord-022526-j9kg00qf 5662 42 Detection Detection NNP cord-022526-j9kg00qf 5662 43 of of IN cord-022526-j9kg00qf 5662 44 serum serum NN cord-022526-j9kg00qf 5662 45 antibodies antibody NNS cord-022526-j9kg00qf 5662 46 against against IN cord-022526-j9kg00qf 5662 47 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 48 risticii risticii NN cord-022526-j9kg00qf 5662 49 in in IN cord-022526-j9kg00qf 5662 50 Potomac Potomac NNP cord-022526-j9kg00qf 5662 51 horse horse NN cord-022526-j9kg00qf 5662 52 fever fever NN cord-022526-j9kg00qf 5662 53 by by IN cord-022526-j9kg00qf 5662 54 enzyme enzyme NN cord-022526-j9kg00qf 5662 55 - - HYPH cord-022526-j9kg00qf 5662 56 linked link VBN cord-022526-j9kg00qf 5662 57 immunosorbent immunosorbent JJ cord-022526-j9kg00qf 5662 58 assay assay NN cord-022526-j9kg00qf 5662 59 Evidence evidence NN cord-022526-j9kg00qf 5662 60 for for IN cord-022526-j9kg00qf 5662 61 a a DT cord-022526-j9kg00qf 5662 62 high high JJ cord-022526-j9kg00qf 5662 63 rate rate NN cord-022526-j9kg00qf 5662 64 of of IN cord-022526-j9kg00qf 5662 65 false false JJ cord-022526-j9kg00qf 5662 66 - - HYPH cord-022526-j9kg00qf 5662 67 positive positive JJ cord-022526-j9kg00qf 5662 68 results result NNS cord-022526-j9kg00qf 5662 69 with with IN cord-022526-j9kg00qf 5662 70 the the DT cord-022526-j9kg00qf 5662 71 indirect indirect JJ cord-022526-j9kg00qf 5662 72 fluorescent fluorescent JJ cord-022526-j9kg00qf 5662 73 antibody antibody NN cord-022526-j9kg00qf 5662 74 test test NN cord-022526-j9kg00qf 5662 75 for for IN cord-022526-j9kg00qf 5662 76 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 77 risticii risticii JJ cord-022526-j9kg00qf 5662 78 antibody antibody NN cord-022526-j9kg00qf 5662 79 in in IN cord-022526-j9kg00qf 5662 80 horses horse NNS cord-022526-j9kg00qf 5662 81 Detection detection NN cord-022526-j9kg00qf 5662 82 and and CC cord-022526-j9kg00qf 5662 83 quantitation quantitation NN cord-022526-j9kg00qf 5662 84 of of IN cord-022526-j9kg00qf 5662 85 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 86 risticii risticii NN cord-022526-j9kg00qf 5662 87 genomic genomic JJ cord-022526-j9kg00qf 5662 88 DNA dna NN cord-022526-j9kg00qf 5662 89 in in IN cord-022526-j9kg00qf 5662 90 infected infected JJ cord-022526-j9kg00qf 5662 91 horses horse NNS cord-022526-j9kg00qf 5662 92 and and CC cord-022526-j9kg00qf 5662 93 snails snail NNS cord-022526-j9kg00qf 5662 94 by by IN cord-022526-j9kg00qf 5662 95 real real JJ cord-022526-j9kg00qf 5662 96 - - HYPH cord-022526-j9kg00qf 5662 97 time time NN cord-022526-j9kg00qf 5662 98 PCR PCR NNP cord-022526-j9kg00qf 5662 99 Comparison Comparison NNP cord-022526-j9kg00qf 5662 100 of of IN cord-022526-j9kg00qf 5662 101 PCR PCR NNP cord-022526-j9kg00qf 5662 102 and and CC cord-022526-j9kg00qf 5662 103 culture culture NN cord-022526-j9kg00qf 5662 104 to to IN cord-022526-j9kg00qf 5662 105 the the DT cord-022526-j9kg00qf 5662 106 indirect indirect JJ cord-022526-j9kg00qf 5662 107 fluorescent fluorescent JJ cord-022526-j9kg00qf 5662 108 - - HYPH cord-022526-j9kg00qf 5662 109 antibody antibody NN cord-022526-j9kg00qf 5662 110 test test NN cord-022526-j9kg00qf 5662 111 for for IN cord-022526-j9kg00qf 5662 112 diagnosis diagnosis NN cord-022526-j9kg00qf 5662 113 of of IN cord-022526-j9kg00qf 5662 114 Potomac Potomac NNP cord-022526-j9kg00qf 5662 115 horse horse NN cord-022526-j9kg00qf 5662 116 fever fever NN cord-022526-j9kg00qf 5662 117 Diagnostic diagnostic JJ cord-022526-j9kg00qf 5662 118 application application NN cord-022526-j9kg00qf 5662 119 of of IN cord-022526-j9kg00qf 5662 120 polymerase polymerase NN cord-022526-j9kg00qf 5662 121 chain chain NN cord-022526-j9kg00qf 5662 122 reaction reaction NN cord-022526-j9kg00qf 5662 123 for for IN cord-022526-j9kg00qf 5662 124 detection detection NN cord-022526-j9kg00qf 5662 125 of of IN cord-022526-j9kg00qf 5662 126 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5662 127 risticii risticii NN cord-022526-j9kg00qf 5662 128 in in IN cord-022526-j9kg00qf 5662 129 equine equine JJ cord-022526-j9kg00qf 5662 130 monocytic monocytic JJ cord-022526-j9kg00qf 5662 131 ehrlichiosis ehrlichiosis NN cord-022526-j9kg00qf 5663 1 ( ( -LRB- cord-022526-j9kg00qf 5663 2 Potomac Potomac NNP cord-022526-j9kg00qf 5663 3 horse horse NN cord-022526-j9kg00qf 5663 4 fever fever NN cord-022526-j9kg00qf 5663 5 ) ) -RRB- cord-022526-j9kg00qf 5663 6 Evaluation evaluation NN cord-022526-j9kg00qf 5663 7 of of IN cord-022526-j9kg00qf 5663 8 vaccination vaccination NN cord-022526-j9kg00qf 5663 9 of of IN cord-022526-j9kg00qf 5663 10 horses horse NNS cord-022526-j9kg00qf 5663 11 as as IN cord-022526-j9kg00qf 5663 12 a a DT cord-022526-j9kg00qf 5663 13 strategy strategy NN cord-022526-j9kg00qf 5663 14 to to TO cord-022526-j9kg00qf 5663 15 control control VB cord-022526-j9kg00qf 5663 16 equine equine NN cord-022526-j9kg00qf 5663 17 monocytic monocytic NNP cord-022526-j9kg00qf 5663 18 ehrlichiosis ehrlichiosis NNP cord-022526-j9kg00qf 5663 19 Association Association NNP cord-022526-j9kg00qf 5663 20 of of IN cord-022526-j9kg00qf 5663 21 deficiency deficiency NN cord-022526-j9kg00qf 5663 22 in in IN cord-022526-j9kg00qf 5663 23 antibody antibody NN cord-022526-j9kg00qf 5663 24 response response NN cord-022526-j9kg00qf 5663 25 to to IN cord-022526-j9kg00qf 5663 26 vaccine vaccine NN cord-022526-j9kg00qf 5663 27 and and CC cord-022526-j9kg00qf 5663 28 heterogeneity heterogeneity NN cord-022526-j9kg00qf 5663 29 of of IN cord-022526-j9kg00qf 5663 30 Ehrlichia Ehrlichia NNP cord-022526-j9kg00qf 5663 31 risticii risticii NN cord-022526-j9kg00qf 5663 32 strains strain NNS cord-022526-j9kg00qf 5663 33 with with IN cord-022526-j9kg00qf 5663 34 Potomac Potomac NNP cord-022526-j9kg00qf 5663 35 horse horse NN cord-022526-j9kg00qf 5663 36 fever fever NN cord-022526-j9kg00qf 5663 37 vaccine vaccine NN cord-022526-j9kg00qf 5663 38 failure failure NN cord-022526-j9kg00qf 5663 39 in in IN cord-022526-j9kg00qf 5663 40 horses horse NNS cord-022526-j9kg00qf 5664 1 Equine equine JJ cord-022526-j9kg00qf 5664 2 intestinal intestinal JJ cord-022526-j9kg00qf 5664 3 clostridiosis clostridiosis NN cord-022526-j9kg00qf 5664 4 : : : cord-022526-j9kg00qf 5664 5 an an DT cord-022526-j9kg00qf 5664 6 acute acute JJ cord-022526-j9kg00qf 5664 7 disease disease NN cord-022526-j9kg00qf 5664 8 in in IN cord-022526-j9kg00qf 5664 9 horses horse NNS cord-022526-j9kg00qf 5664 10 associated associate VBN cord-022526-j9kg00qf 5664 11 with with IN cord-022526-j9kg00qf 5664 12 high high JJ cord-022526-j9kg00qf 5664 13 intestinal intestinal JJ cord-022526-j9kg00qf 5664 14 counts count NNS cord-022526-j9kg00qf 5664 15 of of IN cord-022526-j9kg00qf 5664 16 Clostridium clostridium NN cord-022526-j9kg00qf 5664 17 perfringens perfringens NN cord-022526-j9kg00qf 5664 18 type type NN cord-022526-j9kg00qf 5664 19 A a NN cord-022526-j9kg00qf 5664 20 A a DT cord-022526-j9kg00qf 5664 21 method method NN cord-022526-j9kg00qf 5664 22 for for IN cord-022526-j9kg00qf 5664 23 reproducing reproduce VBG cord-022526-j9kg00qf 5664 24 fatal fatal JJ cord-022526-j9kg00qf 5664 25 idiopathic idiopathic JJ cord-022526-j9kg00qf 5664 26 colitis colitis NN cord-022526-j9kg00qf 5664 27 ( ( -LRB- cord-022526-j9kg00qf 5664 28 colitis colitis NN cord-022526-j9kg00qf 5664 29 X x NN cord-022526-j9kg00qf 5664 30 ) ) -RRB- cord-022526-j9kg00qf 5664 31 in in IN cord-022526-j9kg00qf 5664 32 ponies pony NNS cord-022526-j9kg00qf 5664 33 and and CC cord-022526-j9kg00qf 5664 34 isolation isolation NN cord-022526-j9kg00qf 5664 35 of of IN cord-022526-j9kg00qf 5664 36 a a DT cord-022526-j9kg00qf 5664 37 clostridium clostridium NN cord-022526-j9kg00qf 5664 38 as as IN cord-022526-j9kg00qf 5664 39 a a DT cord-022526-j9kg00qf 5664 40 possible possible JJ cord-022526-j9kg00qf 5664 41 agent agent NN cord-022526-j9kg00qf 5664 42 Hemorrhagic hemorrhagic JJ cord-022526-j9kg00qf 5664 43 necrotizing necrotize VBG cord-022526-j9kg00qf 5664 44 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5664 45 associated associate VBN cord-022526-j9kg00qf 5664 46 with with IN cord-022526-j9kg00qf 5664 47 Clostridium clostridium NN cord-022526-j9kg00qf 5664 48 difficile difficile NN cord-022526-j9kg00qf 5664 49 infection infection NN cord-022526-j9kg00qf 5664 50 in in IN cord-022526-j9kg00qf 5664 51 four four CD cord-022526-j9kg00qf 5664 52 foals foal NNS cord-022526-j9kg00qf 5664 53 Apparent apparent JJ cord-022526-j9kg00qf 5664 54 outbreaks outbreak NNS cord-022526-j9kg00qf 5664 55 of of IN cord-022526-j9kg00qf 5664 56 Clostridium clostridium NN cord-022526-j9kg00qf 5664 57 difficile difficile NN cord-022526-j9kg00qf 5664 58 - - HYPH cord-022526-j9kg00qf 5664 59 associated associate VBN cord-022526-j9kg00qf 5664 60 diarrhea diarrhea NN cord-022526-j9kg00qf 5664 61 in in IN cord-022526-j9kg00qf 5664 62 horses horse NNS cord-022526-j9kg00qf 5664 63 in in IN cord-022526-j9kg00qf 5664 64 a a DT cord-022526-j9kg00qf 5664 65 veterinary veterinary JJ cord-022526-j9kg00qf 5664 66 medical medical JJ cord-022526-j9kg00qf 5664 67 teaching teaching NN cord-022526-j9kg00qf 5664 68 hospital hospital NN cord-022526-j9kg00qf 5665 1 A a DT cord-022526-j9kg00qf 5665 2 prospective prospective JJ cord-022526-j9kg00qf 5665 3 study study NN cord-022526-j9kg00qf 5665 4 of of IN cord-022526-j9kg00qf 5665 5 the the DT cord-022526-j9kg00qf 5665 6 roles role NNS cord-022526-j9kg00qf 5665 7 of of IN cord-022526-j9kg00qf 5665 8 Clostridium clostridium NN cord-022526-j9kg00qf 5665 9 difficile difficile NN cord-022526-j9kg00qf 5665 10 and and CC cord-022526-j9kg00qf 5665 11 enterotoxigenic enterotoxigenic JJ cord-022526-j9kg00qf 5665 12 Clostridium Clostridium NNP cord-022526-j9kg00qf 5665 13 perfringens perfringen NNS cord-022526-j9kg00qf 5665 14 in in IN cord-022526-j9kg00qf 5665 15 equine equine JJ cord-022526-j9kg00qf 5665 16 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5665 17 Clostridial Clostridial NNP cord-022526-j9kg00qf 5665 18 enterocolitis enterocolitis NN cord-022526-j9kg00qf 5665 19 Prevalence prevalence NN cord-022526-j9kg00qf 5665 20 of of IN cord-022526-j9kg00qf 5665 21 Clostridium clostridium NN cord-022526-j9kg00qf 5665 22 perfringens perfringens NN cord-022526-j9kg00qf 5665 23 enterotoxin enterotoxin NN cord-022526-j9kg00qf 5665 24 and and CC cord-022526-j9kg00qf 5665 25 Clostridium clostridium NN cord-022526-j9kg00qf 5665 26 difficile difficile NN cord-022526-j9kg00qf 5665 27 toxin toxin NN cord-022526-j9kg00qf 5665 28 A a NN cord-022526-j9kg00qf 5665 29 in in IN cord-022526-j9kg00qf 5665 30 feces fece NNS cord-022526-j9kg00qf 5665 31 of of IN cord-022526-j9kg00qf 5665 32 horses horse NNS cord-022526-j9kg00qf 5665 33 with with IN cord-022526-j9kg00qf 5665 34 diarrhea diarrhea NN cord-022526-j9kg00qf 5665 35 and and CC cord-022526-j9kg00qf 5665 36 colic colic NN cord-022526-j9kg00qf 5666 1 Clostridium clostridium NN cord-022526-j9kg00qf 5666 2 difficile difficile NN cord-022526-j9kg00qf 5666 3 associated associate VBN cord-022526-j9kg00qf 5666 4 with with IN cord-022526-j9kg00qf 5666 5 acute acute JJ cord-022526-j9kg00qf 5666 6 colitis colitis NN cord-022526-j9kg00qf 5666 7 in in IN cord-022526-j9kg00qf 5666 8 mature mature JJ cord-022526-j9kg00qf 5666 9 horses horse NNS cord-022526-j9kg00qf 5666 10 treated treat VBN cord-022526-j9kg00qf 5666 11 with with IN cord-022526-j9kg00qf 5666 12 antibiotics antibiotic NNS cord-022526-j9kg00qf 5667 1 The the DT cord-022526-j9kg00qf 5667 2 effect effect NN cord-022526-j9kg00qf 5667 3 of of IN cord-022526-j9kg00qf 5667 4 colic colic NN cord-022526-j9kg00qf 5667 5 on on IN cord-022526-j9kg00qf 5667 6 the the DT cord-022526-j9kg00qf 5667 7 microbial microbial JJ cord-022526-j9kg00qf 5667 8 activity activity NN cord-022526-j9kg00qf 5667 9 of of IN cord-022526-j9kg00qf 5667 10 the the DT cord-022526-j9kg00qf 5667 11 equine equine JJ cord-022526-j9kg00qf 5667 12 intestine intestine NN cord-022526-j9kg00qf 5667 13 Comparative comparative JJ cord-022526-j9kg00qf 5667 14 effects effect NNS cord-022526-j9kg00qf 5667 15 of of IN cord-022526-j9kg00qf 5667 16 oral oral JJ cord-022526-j9kg00qf 5667 17 administration administration NN cord-022526-j9kg00qf 5667 18 of of IN cord-022526-j9kg00qf 5667 19 trimethoprim trimethoprim NNP cord-022526-j9kg00qf 5667 20 / / SYM cord-022526-j9kg00qf 5667 21 sulphadiazine sulphadiazine NNP cord-022526-j9kg00qf 5667 22 or or CC cord-022526-j9kg00qf 5667 23 oxytetracycline oxytetracycline NN cord-022526-j9kg00qf 5667 24 on on IN cord-022526-j9kg00qf 5667 25 the the DT cord-022526-j9kg00qf 5667 26 faecal faecal JJ cord-022526-j9kg00qf 5667 27 flora flora NNS cord-022526-j9kg00qf 5667 28 of of IN cord-022526-j9kg00qf 5667 29 horses horse NNS cord-022526-j9kg00qf 5668 1 Colonic colonic JJ cord-022526-j9kg00qf 5668 2 fermentation fermentation NN cord-022526-j9kg00qf 5668 3 to to IN cord-022526-j9kg00qf 5668 4 short short JJ cord-022526-j9kg00qf 5668 5 - - HYPH cord-022526-j9kg00qf 5668 6 chain chain NN cord-022526-j9kg00qf 5668 7 fatty fatty JJ cord-022526-j9kg00qf 5668 8 acids acid NNS cord-022526-j9kg00qf 5668 9 is be VBZ cord-022526-j9kg00qf 5668 10 decreased decrease VBN cord-022526-j9kg00qf 5668 11 in in IN cord-022526-j9kg00qf 5668 12 antibiotic antibiotic NN cord-022526-j9kg00qf 5668 13 - - HYPH cord-022526-j9kg00qf 5668 14 associated associate VBN cord-022526-j9kg00qf 5668 15 diarrhea diarrhea NN cord-022526-j9kg00qf 5668 16 Clostridium clostridium NN cord-022526-j9kg00qf 5668 17 difficile difficile NN cord-022526-j9kg00qf 5668 18 associated associate VBN cord-022526-j9kg00qf 5668 19 with with IN cord-022526-j9kg00qf 5668 20 acute acute JJ cord-022526-j9kg00qf 5668 21 colitis colitis NN cord-022526-j9kg00qf 5668 22 in in IN cord-022526-j9kg00qf 5668 23 mares mare NNS cord-022526-j9kg00qf 5668 24 when when WRB cord-022526-j9kg00qf 5668 25 their -PRON- PRP$ cord-022526-j9kg00qf 5668 26 foals foal NNS cord-022526-j9kg00qf 5668 27 are be VBP cord-022526-j9kg00qf 5668 28 treated treat VBN cord-022526-j9kg00qf 5668 29 with with IN cord-022526-j9kg00qf 5668 30 erythromycin erythromycin NN cord-022526-j9kg00qf 5668 31 and and CC cord-022526-j9kg00qf 5668 32 rifampicin rifampicin NNS cord-022526-j9kg00qf 5668 33 for for IN cord-022526-j9kg00qf 5668 34 Rhodococcus Rhodococcus NNP cord-022526-j9kg00qf 5668 35 equi equi NN cord-022526-j9kg00qf 5668 36 pneumonia pneumonia NN cord-022526-j9kg00qf 5668 37 Lincomycin Lincomycin NNP cord-022526-j9kg00qf 5668 38 - - HYPH cord-022526-j9kg00qf 5668 39 induced induce VBN cord-022526-j9kg00qf 5668 40 severe severe JJ cord-022526-j9kg00qf 5668 41 colitis colitis NN cord-022526-j9kg00qf 5668 42 in in IN cord-022526-j9kg00qf 5668 43 ponies pony NNS cord-022526-j9kg00qf 5668 44 : : : cord-022526-j9kg00qf 5668 45 association association NN cord-022526-j9kg00qf 5668 46 with with IN cord-022526-j9kg00qf 5668 47 Clostridium Clostridium NNP cord-022526-j9kg00qf 5668 48 cadaveris cadaveris NNP cord-022526-j9kg00qf 5669 1 An an DT cord-022526-j9kg00qf 5669 2 investigation investigation NN cord-022526-j9kg00qf 5669 3 into into IN cord-022526-j9kg00qf 5669 4 Clostridium clostridium NN cord-022526-j9kg00qf 5669 5 perfringens perfringens NN cord-022526-j9kg00qf 5669 6 enterotoxin enterotoxin NN cord-022526-j9kg00qf 5669 7 - - HYPH cord-022526-j9kg00qf 5669 8 associated associate VBN cord-022526-j9kg00qf 5669 9 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5669 10 Enterotoxigenic Enterotoxigenic NNP cord-022526-j9kg00qf 5669 11 Clostridium Clostridium NNP cord-022526-j9kg00qf 5669 12 perfringens perfringen VBZ cord-022526-j9kg00qf 5669 13 Esophageal esophageal NN cord-022526-j9kg00qf 5669 14 duplication duplication NN cord-022526-j9kg00qf 5669 15 cyst cyst NN cord-022526-j9kg00qf 5669 16 as as IN cord-022526-j9kg00qf 5669 17 a a DT cord-022526-j9kg00qf 5669 18 cause cause NN cord-022526-j9kg00qf 5669 19 of of IN cord-022526-j9kg00qf 5669 20 choke choke NN cord-022526-j9kg00qf 5669 21 in in IN cord-022526-j9kg00qf 5669 22 the the DT cord-022526-j9kg00qf 5669 23 horse horse NN cord-022526-j9kg00qf 5669 24 Beta2 Beta2 NNS cord-022526-j9kg00qf 5669 25 toxin toxin NN cord-022526-j9kg00qf 5669 26 , , , cord-022526-j9kg00qf 5669 27 a a DT cord-022526-j9kg00qf 5669 28 novel novel JJ cord-022526-j9kg00qf 5669 29 toxin toxin NN cord-022526-j9kg00qf 5669 30 produced produce VBN cord-022526-j9kg00qf 5669 31 by by IN cord-022526-j9kg00qf 5669 32 Clostridium clostridium NN cord-022526-j9kg00qf 5669 33 perfringens perfringens NN cord-022526-j9kg00qf 5669 34 Prevalence prevalence NN cord-022526-j9kg00qf 5669 35 of of IN cord-022526-j9kg00qf 5669 36 beta2-toxigenic beta2-toxigenic CC cord-022526-j9kg00qf 5669 37 Clostridium clostridium NN cord-022526-j9kg00qf 5669 38 perfringens perfringen NNS cord-022526-j9kg00qf 5669 39 in in IN cord-022526-j9kg00qf 5669 40 horses horse NNS cord-022526-j9kg00qf 5669 41 with with IN cord-022526-j9kg00qf 5669 42 intestinal intestinal JJ cord-022526-j9kg00qf 5669 43 disorders disorder NNS cord-022526-j9kg00qf 5670 1 An an DT cord-022526-j9kg00qf 5670 2 overview overview NN cord-022526-j9kg00qf 5670 3 of of IN cord-022526-j9kg00qf 5670 4 Clostridium clostridium NN cord-022526-j9kg00qf 5670 5 perfringens perfringens NN cord-022526-j9kg00qf 5670 6 enterotoxin enterotoxin NNP cord-022526-j9kg00qf 5671 1 The the DT cord-022526-j9kg00qf 5671 2 effects effect NNS cord-022526-j9kg00qf 5671 3 of of IN cord-022526-j9kg00qf 5671 4 Clostridium clostridium NN cord-022526-j9kg00qf 5671 5 perfringens perfringens NN cord-022526-j9kg00qf 5671 6 type type NN cord-022526-j9kg00qf 5671 7 A a NN cord-022526-j9kg00qf 5671 8 enterotoxin enterotoxin NN cord-022526-j9kg00qf 5671 9 in in IN cord-022526-j9kg00qf 5671 10 Shetland Shetland NNP cord-022526-j9kg00qf 5671 11 ponies pony NNS cord-022526-j9kg00qf 5671 12 : : : cord-022526-j9kg00qf 5671 13 clinical clinical JJ cord-022526-j9kg00qf 5671 14 , , , cord-022526-j9kg00qf 5671 15 morphologic morphologic JJ cord-022526-j9kg00qf 5671 16 and and CC cord-022526-j9kg00qf 5671 17 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 5671 18 changes change NNS cord-022526-j9kg00qf 5672 1 An an DT cord-022526-j9kg00qf 5672 2 update update NN cord-022526-j9kg00qf 5672 3 on on IN cord-022526-j9kg00qf 5672 4 Clostridium clostridium NN cord-022526-j9kg00qf 5672 5 perfringens perfringens NN cord-022526-j9kg00qf 5672 6 enterotoxin enterotoxin NNP cord-022526-j9kg00qf 5672 7 Clostridium clostridium NN cord-022526-j9kg00qf 5672 8 difficile difficile NN cord-022526-j9kg00qf 5672 9 infection infection NN cord-022526-j9kg00qf 5673 1 Direct direct JJ cord-022526-j9kg00qf 5673 2 evidence evidence NN cord-022526-j9kg00qf 5673 3 of of IN cord-022526-j9kg00qf 5673 4 mast mast JJ cord-022526-j9kg00qf 5673 5 cell cell NN cord-022526-j9kg00qf 5673 6 involvement involvement NN cord-022526-j9kg00qf 5673 7 in in IN cord-022526-j9kg00qf 5673 8 Clostridium clostridium NN cord-022526-j9kg00qf 5673 9 difficile difficile NN cord-022526-j9kg00qf 5673 10 toxin toxin NN cord-022526-j9kg00qf 5673 11 A a NN cord-022526-j9kg00qf 5673 12 - - HYPH cord-022526-j9kg00qf 5673 13 induced induce VBN cord-022526-j9kg00qf 5673 14 enteritis enteritis NN cord-022526-j9kg00qf 5673 15 in in IN cord-022526-j9kg00qf 5673 16 mice mouse NNS cord-022526-j9kg00qf 5673 17 Neutrophil Neutrophil NNP cord-022526-j9kg00qf 5673 18 recruitment recruitment NN cord-022526-j9kg00qf 5673 19 in in IN cord-022526-j9kg00qf 5673 20 Clostridium clostridium NN cord-022526-j9kg00qf 5673 21 difficile difficile NN cord-022526-j9kg00qf 5673 22 toxin toxin NN cord-022526-j9kg00qf 5674 1 A a DT cord-022526-j9kg00qf 5674 2 enteritis enteritis NN cord-022526-j9kg00qf 5674 3 in in IN cord-022526-j9kg00qf 5674 4 the the DT cord-022526-j9kg00qf 5674 5 rabbit rabbit NN cord-022526-j9kg00qf 5674 6 Neuronal neuronal JJ cord-022526-j9kg00qf 5674 7 involvement involvement NN cord-022526-j9kg00qf 5674 8 in in IN cord-022526-j9kg00qf 5674 9 the the DT cord-022526-j9kg00qf 5674 10 intestinal intestinal JJ cord-022526-j9kg00qf 5674 11 effects effect NNS cord-022526-j9kg00qf 5674 12 of of IN cord-022526-j9kg00qf 5674 13 Clostridium clostridium NN cord-022526-j9kg00qf 5674 14 difficile difficile NN cord-022526-j9kg00qf 5674 15 toxin toxin NN cord-022526-j9kg00qf 5674 16 A a NN cord-022526-j9kg00qf 5674 17 and and CC cord-022526-j9kg00qf 5674 18 Vibrio Vibrio NNP cord-022526-j9kg00qf 5674 19 cholerae cholerae NN cord-022526-j9kg00qf 5674 20 enterotoxin enterotoxin XX cord-022526-j9kg00qf 5674 21 in in IN cord-022526-j9kg00qf 5674 22 rat rat NN cord-022526-j9kg00qf 5674 23 ileum ileum NN cord-022526-j9kg00qf 5674 24 Increased increase VBN cord-022526-j9kg00qf 5674 25 substance substance NN cord-022526-j9kg00qf 5674 26 P p NN cord-022526-j9kg00qf 5674 27 responses response NNS cord-022526-j9kg00qf 5674 28 in in IN cord-022526-j9kg00qf 5674 29 dorsal dorsal JJ cord-022526-j9kg00qf 5674 30 root root NN cord-022526-j9kg00qf 5674 31 ganglia ganglion NNS cord-022526-j9kg00qf 5674 32 and and CC cord-022526-j9kg00qf 5674 33 intestinal intestinal JJ cord-022526-j9kg00qf 5674 34 macrophages macrophage NNS cord-022526-j9kg00qf 5674 35 during during IN cord-022526-j9kg00qf 5674 36 Clostridium clostridium NN cord-022526-j9kg00qf 5674 37 difficile difficile NN cord-022526-j9kg00qf 5674 38 toxin toxin NN cord-022526-j9kg00qf 5675 1 A a DT cord-022526-j9kg00qf 5675 2 enteritis enteritis NN cord-022526-j9kg00qf 5675 3 in in IN cord-022526-j9kg00qf 5675 4 rats rat NNS cord-022526-j9kg00qf 5676 1 CP-96,345 CP-96,345 NNP cord-022526-j9kg00qf 5676 2 , , , cord-022526-j9kg00qf 5676 3 a a DT cord-022526-j9kg00qf 5676 4 substance substance NN cord-022526-j9kg00qf 5676 5 P p NN cord-022526-j9kg00qf 5676 6 antagonist antagonist NN cord-022526-j9kg00qf 5676 7 , , , cord-022526-j9kg00qf 5676 8 inhibits inhibit VBZ cord-022526-j9kg00qf 5676 9 rat rat NN cord-022526-j9kg00qf 5676 10 intestinal intestinal JJ cord-022526-j9kg00qf 5676 11 responses response NNS cord-022526-j9kg00qf 5676 12 to to IN cord-022526-j9kg00qf 5676 13 Intestinal intestinal JJ cord-022526-j9kg00qf 5676 14 infarction infarction NN cord-022526-j9kg00qf 5676 15 associated associate VBN cord-022526-j9kg00qf 5676 16 with with IN cord-022526-j9kg00qf 5676 17 mesenteric mesenteric JJ cord-022526-j9kg00qf 5676 18 vascular vascular JJ cord-022526-j9kg00qf 5676 19 thrombotic thrombotic JJ cord-022526-j9kg00qf 5676 20 disease disease NN cord-022526-j9kg00qf 5676 21 in in IN cord-022526-j9kg00qf 5676 22 the the DT cord-022526-j9kg00qf 5676 23 horse horse NN cord-022526-j9kg00qf 5677 1 The the DT cord-022526-j9kg00qf 5677 2 role role NN cord-022526-j9kg00qf 5677 3 of of IN cord-022526-j9kg00qf 5677 4 parasites parasite NNS cord-022526-j9kg00qf 5677 5 in in IN cord-022526-j9kg00qf 5677 6 colic colic NN cord-022526-j9kg00qf 5677 7 Retropulsion retropulsion NN cord-022526-j9kg00qf 5677 8 - - HYPH cord-022526-j9kg00qf 5677 9 propulsion propulsion NN cord-022526-j9kg00qf 5677 10 in in IN cord-022526-j9kg00qf 5677 11 equine equine JJ cord-022526-j9kg00qf 5677 12 large large JJ cord-022526-j9kg00qf 5677 13 colon colon NN cord-022526-j9kg00qf 5677 14 Diarrhoea diarrhoea NN cord-022526-j9kg00qf 5677 15 in in IN cord-022526-j9kg00qf 5677 16 horses horse NNS cord-022526-j9kg00qf 5677 17 associated associate VBN cord-022526-j9kg00qf 5677 18 with with IN cord-022526-j9kg00qf 5677 19 ulceration ulceration NN cord-022526-j9kg00qf 5677 20 of of IN cord-022526-j9kg00qf 5677 21 the the DT cord-022526-j9kg00qf 5677 22 colon colon NN cord-022526-j9kg00qf 5677 23 and and CC cord-022526-j9kg00qf 5677 24 caecum caecum NN cord-022526-j9kg00qf 5677 25 resulting result VBG cord-022526-j9kg00qf 5677 26 from from IN cord-022526-j9kg00qf 5677 27 S. S. NNP cord-022526-j9kg00qf 5677 28 vulgaris vulgaris NN cord-022526-j9kg00qf 5677 29 larval larval JJ cord-022526-j9kg00qf 5677 30 migration migration NN cord-022526-j9kg00qf 5677 31 Clinical clinical JJ cord-022526-j9kg00qf 5677 32 response response NN cord-022526-j9kg00qf 5677 33 of of IN cord-022526-j9kg00qf 5677 34 pony pony NN cord-022526-j9kg00qf 5677 35 foals foal NNS cord-022526-j9kg00qf 5677 36 experimentally experimentally RB cord-022526-j9kg00qf 5677 37 infected infect VBN cord-022526-j9kg00qf 5677 38 with with IN cord-022526-j9kg00qf 5677 39 Strongylus Strongylus NNP cord-022526-j9kg00qf 5677 40 vulgaris vulgaris NN cord-022526-j9kg00qf 5677 41 Host Host NNP cord-022526-j9kg00qf 5677 42 response response NN cord-022526-j9kg00qf 5677 43 to to IN cord-022526-j9kg00qf 5677 44 experimentally experimentally RB cord-022526-j9kg00qf 5677 45 induced induce VBN cord-022526-j9kg00qf 5677 46 infections infection NNS cord-022526-j9kg00qf 5677 47 of of IN cord-022526-j9kg00qf 5677 48 Strongylus Strongylus NNP cord-022526-j9kg00qf 5677 49 vulgaris vulgaris NN cord-022526-j9kg00qf 5677 50 in in IN cord-022526-j9kg00qf 5677 51 parasite parasite NN cord-022526-j9kg00qf 5677 52 - - HYPH cord-022526-j9kg00qf 5677 53 free free JJ cord-022526-j9kg00qf 5677 54 and and CC cord-022526-j9kg00qf 5677 55 naturally naturally RB cord-022526-j9kg00qf 5677 56 infected infected JJ cord-022526-j9kg00qf 5677 57 ponies pony NNS cord-022526-j9kg00qf 5677 58 Morphologic morphologic JJ cord-022526-j9kg00qf 5677 59 and and CC cord-022526-j9kg00qf 5677 60 clinicopathologic clinicopathologic JJ cord-022526-j9kg00qf 5677 61 changes change NNS cord-022526-j9kg00qf 5677 62 following follow VBG cord-022526-j9kg00qf 5677 63 Strongylus Strongylus NNP cord-022526-j9kg00qf 5677 64 vulgaris vulgaris NN cord-022526-j9kg00qf 5677 65 infections infection NNS cord-022526-j9kg00qf 5677 66 of of IN cord-022526-j9kg00qf 5678 1 immune immune JJ cord-022526-j9kg00qf 5678 2 and and CC cord-022526-j9kg00qf 5678 3 nonimmune nonimmune JJ cord-022526-j9kg00qf 5678 4 ponies pony NNS cord-022526-j9kg00qf 5678 5 Increase increase VBP cord-022526-j9kg00qf 5678 6 of of IN cord-022526-j9kg00qf 5678 7 immunoglobulin immunoglobulin NN cord-022526-j9kg00qf 5678 8 T t NN cord-022526-j9kg00qf 5678 9 concentration concentration NN cord-022526-j9kg00qf 5678 10 in in IN cord-022526-j9kg00qf 5678 11 ponies pony NNS cord-022526-j9kg00qf 5678 12 as as IN cord-022526-j9kg00qf 5678 13 a a DT cord-022526-j9kg00qf 5678 14 response response NN cord-022526-j9kg00qf 5678 15 to to IN cord-022526-j9kg00qf 5678 16 experimental experimental JJ cord-022526-j9kg00qf 5678 17 infection infection NN cord-022526-j9kg00qf 5678 18 with with IN cord-022526-j9kg00qf 5678 19 the the DT cord-022526-j9kg00qf 5678 20 nematode nematode NN cord-022526-j9kg00qf 5678 21 Strongylus Strongylus NNP cord-022526-j9kg00qf 5678 22 vulgaris vulgaris NN cord-022526-j9kg00qf 5678 23 Larval larval JJ cord-022526-j9kg00qf 5678 24 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 5678 25 Immature immature JJ cord-022526-j9kg00qf 5678 26 stages stage NNS cord-022526-j9kg00qf 5678 27 of of IN cord-022526-j9kg00qf 5678 28 Trichonema Trichonema NNP cord-022526-j9kg00qf 5678 29 spp spp NNP cord-022526-j9kg00qf 5678 30 as as IN cord-022526-j9kg00qf 5678 31 a a DT cord-022526-j9kg00qf 5678 32 cause cause NN cord-022526-j9kg00qf 5678 33 of of IN cord-022526-j9kg00qf 5678 34 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5678 35 in in IN cord-022526-j9kg00qf 5678 36 adult adult NN cord-022526-j9kg00qf 5678 37 horses horse NNS cord-022526-j9kg00qf 5678 38 in in IN cord-022526-j9kg00qf 5678 39 spring spring NN cord-022526-j9kg00qf 5678 40 Larval larval JJ cord-022526-j9kg00qf 5678 41 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 5678 42 ( ( -LRB- cord-022526-j9kg00qf 5678 43 immature immature JJ cord-022526-j9kg00qf 5678 44 Trichonema Trichonema NNP cord-022526-j9kg00qf 5678 45 - - HYPH cord-022526-j9kg00qf 5678 46 induced induce VBN cord-022526-j9kg00qf 5678 47 enteropathy enteropathy NNP cord-022526-j9kg00qf 5678 48 ) ) -RRB- cord-022526-j9kg00qf 5678 49 : : : cord-022526-j9kg00qf 5679 1 a a DT cord-022526-j9kg00qf 5679 2 report report NN cord-022526-j9kg00qf 5679 3 of of IN cord-022526-j9kg00qf 5679 4 15 15 CD cord-022526-j9kg00qf 5679 5 clinical clinical JJ cord-022526-j9kg00qf 5679 6 cases case NNS cord-022526-j9kg00qf 5679 7 Diagnosis diagnosis NN cord-022526-j9kg00qf 5679 8 and and CC cord-022526-j9kg00qf 5679 9 successful successful JJ cord-022526-j9kg00qf 5679 10 treatment treatment NN cord-022526-j9kg00qf 5679 11 of of IN cord-022526-j9kg00qf 5679 12 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5679 13 in in IN cord-022526-j9kg00qf 5679 14 horses horse NNS cord-022526-j9kg00qf 5679 15 caused cause VBN cord-022526-j9kg00qf 5679 16 by by IN cord-022526-j9kg00qf 5679 17 immature immature JJ cord-022526-j9kg00qf 5679 18 small small JJ cord-022526-j9kg00qf 5679 19 strongyles strongyle NNS cord-022526-j9kg00qf 5679 20 apparently apparently RB cord-022526-j9kg00qf 5679 21 insusceptible insusceptible JJ cord-022526-j9kg00qf 5679 22 to to IN cord-022526-j9kg00qf 5679 23 anthelmintics anthelmintics NNP cord-022526-j9kg00qf 5679 24 Recurrent recurrent JJ cord-022526-j9kg00qf 5679 25 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5679 26 in in IN cord-022526-j9kg00qf 5679 27 aged aged JJ cord-022526-j9kg00qf 5679 28 ponies pony NNS cord-022526-j9kg00qf 5679 29 associated associate VBN cord-022526-j9kg00qf 5679 30 with with IN cord-022526-j9kg00qf 5679 31 larval larval JJ cord-022526-j9kg00qf 5679 32 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 5679 33 Outbreak outbreak NN cord-022526-j9kg00qf 5679 34 of of IN cord-022526-j9kg00qf 5679 35 larval larval JJ cord-022526-j9kg00qf 5679 36 cyathostomiasis cyathostomiasis NN cord-022526-j9kg00qf 5679 37 among among IN cord-022526-j9kg00qf 5679 38 a a DT cord-022526-j9kg00qf 5679 39 group group NN cord-022526-j9kg00qf 5679 40 of of IN cord-022526-j9kg00qf 5679 41 yearling yearling NN cord-022526-j9kg00qf 5679 42 and and CC cord-022526-j9kg00qf 5679 43 two two CD cord-022526-j9kg00qf 5679 44 - - HYPH cord-022526-j9kg00qf 5679 45 year year NN cord-022526-j9kg00qf 5679 46 - - HYPH cord-022526-j9kg00qf 5679 47 old old JJ cord-022526-j9kg00qf 5679 48 horses horse NNS cord-022526-j9kg00qf 5679 49 Pathogenicity Pathogenicity NNP cord-022526-j9kg00qf 5679 50 of of IN cord-022526-j9kg00qf 5679 51 cyathostome cyathostome NN cord-022526-j9kg00qf 5679 52 infection infection NN cord-022526-j9kg00qf 5679 53 Chronic Chronic NNP cord-022526-j9kg00qf 5679 54 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5679 55 in in IN cord-022526-j9kg00qf 5679 56 adult adult NN cord-022526-j9kg00qf 5679 57 horses horse NNS cord-022526-j9kg00qf 5679 58 : : : cord-022526-j9kg00qf 5679 59 a a DT cord-022526-j9kg00qf 5679 60 review review NN cord-022526-j9kg00qf 5679 61 of of IN cord-022526-j9kg00qf 5679 62 51 51 CD cord-022526-j9kg00qf 5679 63 referred refer VBN cord-022526-j9kg00qf 5679 64 cases case NNS cord-022526-j9kg00qf 5679 65 Diarrhoea diarrhoea NN cord-022526-j9kg00qf 5679 66 in in IN cord-022526-j9kg00qf 5679 67 adult adult NN cord-022526-j9kg00qf 5679 68 horses horse NNS cord-022526-j9kg00qf 5679 69 : : : cord-022526-j9kg00qf 5679 70 a a DT cord-022526-j9kg00qf 5679 71 survey survey NN cord-022526-j9kg00qf 5679 72 of of IN cord-022526-j9kg00qf 5679 73 clinical clinical JJ cord-022526-j9kg00qf 5679 74 cases case NNS cord-022526-j9kg00qf 5679 75 and and CC cord-022526-j9kg00qf 5679 76 an an DT cord-022526-j9kg00qf 5679 77 assessment assessment NN cord-022526-j9kg00qf 5679 78 of of IN cord-022526-j9kg00qf 5679 79 some some DT cord-022526-j9kg00qf 5679 80 prognostic prognostic JJ cord-022526-j9kg00qf 5679 81 indices index NNS cord-022526-j9kg00qf 5680 1 The the DT cord-022526-j9kg00qf 5680 2 pathogenic pathogenic JJ cord-022526-j9kg00qf 5680 3 effects effect NNS cord-022526-j9kg00qf 5680 4 of of IN cord-022526-j9kg00qf 5680 5 experimental experimental JJ cord-022526-j9kg00qf 5680 6 cyathostome cyathostome NN cord-022526-j9kg00qf 5680 7 infections infection NNS cord-022526-j9kg00qf 5680 8 in in IN cord-022526-j9kg00qf 5680 9 ponies pony NNS cord-022526-j9kg00qf 5680 10 Fructosamine Fructosamine NNP cord-022526-j9kg00qf 5680 11 measurement measurement NN cord-022526-j9kg00qf 5680 12 in in IN cord-022526-j9kg00qf 5680 13 ponies pony NNS cord-022526-j9kg00qf 5680 14 : : : cord-022526-j9kg00qf 5680 15 validation validation NN cord-022526-j9kg00qf 5680 16 and and CC cord-022526-j9kg00qf 5680 17 response response NN cord-022526-j9kg00qf 5680 18 following follow VBG cord-022526-j9kg00qf 5680 19 experimental experimental JJ cord-022526-j9kg00qf 5680 20 cyathostome cyathostome NN cord-022526-j9kg00qf 5680 21 infection infection NN cord-022526-j9kg00qf 5681 1 Re re NN cord-022526-j9kg00qf 5681 2 - - NN cord-022526-j9kg00qf 5681 3 evaluation evaluation NN cord-022526-j9kg00qf 5681 4 of of IN cord-022526-j9kg00qf 5681 5 ivermectin ivermectin NNP cord-022526-j9kg00qf 5681 6 efficacy efficacy NN cord-022526-j9kg00qf 5681 7 against against IN cord-022526-j9kg00qf 5681 8 equine equine JJ cord-022526-j9kg00qf 5681 9 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5681 10 parasites parasite NNS cord-022526-j9kg00qf 5681 11 Prevalence prevalence NN cord-022526-j9kg00qf 5681 12 and and CC cord-022526-j9kg00qf 5681 13 clinical clinical JJ cord-022526-j9kg00qf 5681 14 implications implication NNS cord-022526-j9kg00qf 5681 15 of of IN cord-022526-j9kg00qf 5681 16 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 5681 17 resistance resistance NN cord-022526-j9kg00qf 5681 18 in in IN cord-022526-j9kg00qf 5681 19 cyathostomes cyathostome NNS cord-022526-j9kg00qf 5681 20 of of IN cord-022526-j9kg00qf 5681 21 horses horse NNS cord-022526-j9kg00qf 5682 1 Equine equine JJ cord-022526-j9kg00qf 5682 2 cyathostome cyathostome NN cord-022526-j9kg00qf 5682 3 infection infection NN cord-022526-j9kg00qf 5682 4 : : : cord-022526-j9kg00qf 5682 5 suppression suppression NN cord-022526-j9kg00qf 5682 6 of of IN cord-022526-j9kg00qf 5682 7 faecal faecal JJ cord-022526-j9kg00qf 5682 8 egg egg NN cord-022526-j9kg00qf 5682 9 output output NN cord-022526-j9kg00qf 5682 10 with with IN cord-022526-j9kg00qf 5682 11 moxidectin moxidectin NNP cord-022526-j9kg00qf 5682 12 Experimental experimental JJ cord-022526-j9kg00qf 5682 13 cyathostome cyathostome NN cord-022526-j9kg00qf 5682 14 challenge challenge NN cord-022526-j9kg00qf 5682 15 of of IN cord-022526-j9kg00qf 5682 16 ponies pony NNS cord-022526-j9kg00qf 5682 17 maintained maintain VBN cord-022526-j9kg00qf 5682 18 with with IN cord-022526-j9kg00qf 5682 19 or or CC cord-022526-j9kg00qf 5682 20 without without IN cord-022526-j9kg00qf 5682 21 benefit benefit NN cord-022526-j9kg00qf 5682 22 of of IN cord-022526-j9kg00qf 5682 23 daily daily JJ cord-022526-j9kg00qf 5682 24 pyrantel pyrantel NN cord-022526-j9kg00qf 5682 25 tartrate tartrate NN cord-022526-j9kg00qf 5682 26 feed feed NN cord-022526-j9kg00qf 5682 27 additive additive NN cord-022526-j9kg00qf 5682 28 : : : cord-022526-j9kg00qf 5682 29 comparison comparison NN cord-022526-j9kg00qf 5682 30 of of IN cord-022526-j9kg00qf 5682 31 parasite parasite JJ cord-022526-j9kg00qf 5682 32 burdens burden NNS cord-022526-j9kg00qf 5682 33 , , , cord-022526-j9kg00qf 5682 34 immunity immunity NN cord-022526-j9kg00qf 5682 35 and and CC cord-022526-j9kg00qf 5682 36 colonic colonic JJ cord-022526-j9kg00qf 5682 37 pathology pathology NN cord-022526-j9kg00qf 5682 38 Identification identification NN cord-022526-j9kg00qf 5682 39 and and CC cord-022526-j9kg00qf 5682 40 characterization characterization NN cord-022526-j9kg00qf 5682 41 of of IN cord-022526-j9kg00qf 5682 42 a a DT cord-022526-j9kg00qf 5682 43 pyrantel pyrantel NN cord-022526-j9kg00qf 5682 44 pamoate pamoate NN cord-022526-j9kg00qf 5682 45 resistant resistant JJ cord-022526-j9kg00qf 5682 46 cyathostome cyathostome NN cord-022526-j9kg00qf 5682 47 population population NN cord-022526-j9kg00qf 5682 48 Lethal lethal JJ cord-022526-j9kg00qf 5682 49 complications complication NNS cord-022526-j9kg00qf 5682 50 following follow VBG cord-022526-j9kg00qf 5682 51 administration administration NNP cord-022526-j9kg00qf 5682 52 of of IN cord-022526-j9kg00qf 5682 53 oxytetracycline oxytetracycline NNP cord-022526-j9kg00qf 5682 54 in in IN cord-022526-j9kg00qf 5682 55 the the DT cord-022526-j9kg00qf 5682 56 horse horse NN cord-022526-j9kg00qf 5682 57 Lincomycin Lincomycin NNP cord-022526-j9kg00qf 5682 58 - - HYPH cord-022526-j9kg00qf 5682 59 associated associate VBN cord-022526-j9kg00qf 5682 60 colitis colitis NN cord-022526-j9kg00qf 5682 61 in in IN cord-022526-j9kg00qf 5682 62 horses horse NNS cord-022526-j9kg00qf 5682 63 Risk Risk NNP cord-022526-j9kg00qf 5682 64 of of IN cord-022526-j9kg00qf 5682 65 adverse adverse JJ cord-022526-j9kg00qf 5682 66 effects effect NNS cord-022526-j9kg00qf 5682 67 in in IN cord-022526-j9kg00qf 5682 68 pneumonic pneumonic JJ cord-022526-j9kg00qf 5682 69 foals foal NNS cord-022526-j9kg00qf 5682 70 treated treat VBN cord-022526-j9kg00qf 5682 71 with with IN cord-022526-j9kg00qf 5682 72 erythromycin erythromycin NNS cord-022526-j9kg00qf 5682 73 versus versus IN cord-022526-j9kg00qf 5682 74 other other JJ cord-022526-j9kg00qf 5682 75 antibiotics antibiotic NNS cord-022526-j9kg00qf 5682 76 : : : cord-022526-j9kg00qf 5682 77 143 143 CD cord-022526-j9kg00qf 5682 78 cases case NNS cord-022526-j9kg00qf 5682 79 ( ( -LRB- cord-022526-j9kg00qf 5682 80 1986 1986 CD cord-022526-j9kg00qf 5682 81 - - SYM cord-022526-j9kg00qf 5682 82 1996 1996 CD cord-022526-j9kg00qf 5682 83 ) ) -RRB- cord-022526-j9kg00qf 5683 1 Case case NN cord-022526-j9kg00qf 5683 2 control control NN cord-022526-j9kg00qf 5683 3 and and CC cord-022526-j9kg00qf 5683 4 historical historical JJ cord-022526-j9kg00qf 5683 5 cohort cohort NN cord-022526-j9kg00qf 5683 6 study study NN cord-022526-j9kg00qf 5683 7 of of IN cord-022526-j9kg00qf 5683 8 diarrhea diarrhea NN cord-022526-j9kg00qf 5683 9 associated associate VBN cord-022526-j9kg00qf 5683 10 with with IN cord-022526-j9kg00qf 5683 11 administration administration NN cord-022526-j9kg00qf 5683 12 of of IN cord-022526-j9kg00qf 5683 13 trimethoprim trimethoprim NNP cord-022526-j9kg00qf 5683 14 - - HYPH cord-022526-j9kg00qf 5683 15 potentiated potentiate VBN cord-022526-j9kg00qf 5683 16 sulphonamides sulphonamide NNS cord-022526-j9kg00qf 5683 17 to to IN cord-022526-j9kg00qf 5683 18 horses horse NNS cord-022526-j9kg00qf 5683 19 and and CC cord-022526-j9kg00qf 5683 20 ponies pony NNS cord-022526-j9kg00qf 5684 1 The the DT cord-022526-j9kg00qf 5684 2 association association NN cord-022526-j9kg00qf 5684 3 of of IN cord-022526-j9kg00qf 5684 4 erythromycin erythromycin NNP cord-022526-j9kg00qf 5684 5 ethylsuccinate ethylsuccinate NNP cord-022526-j9kg00qf 5684 6 with with IN cord-022526-j9kg00qf 5684 7 acute acute JJ cord-022526-j9kg00qf 5684 8 colitis colitis NN cord-022526-j9kg00qf 5684 9 in in IN cord-022526-j9kg00qf 5684 10 horses horse NNS cord-022526-j9kg00qf 5684 11 in in IN cord-022526-j9kg00qf 5684 12 Sweden Sweden NNP cord-022526-j9kg00qf 5684 13 Effects effect NNS cord-022526-j9kg00qf 5684 14 of of IN cord-022526-j9kg00qf 5684 15 transportation transportation NN cord-022526-j9kg00qf 5684 16 , , , cord-022526-j9kg00qf 5684 17 surgery surgery NN cord-022526-j9kg00qf 5684 18 , , , cord-022526-j9kg00qf 5684 19 and and CC cord-022526-j9kg00qf 5684 20 antibiotic antibiotic JJ cord-022526-j9kg00qf 5684 21 therapy therapy NN cord-022526-j9kg00qf 5684 22 in in IN cord-022526-j9kg00qf 5684 23 ponies pony NNS cord-022526-j9kg00qf 5684 24 infected infect VBN cord-022526-j9kg00qf 5684 25 with with IN cord-022526-j9kg00qf 5684 26 Salmonella Salmonella NNP cord-022526-j9kg00qf 5685 1 The the DT cord-022526-j9kg00qf 5685 2 influence influence NN cord-022526-j9kg00qf 5685 3 of of IN cord-022526-j9kg00qf 5685 4 the the DT cord-022526-j9kg00qf 5685 5 normal normal JJ cord-022526-j9kg00qf 5685 6 flora flora NNS cord-022526-j9kg00qf 5685 7 on on IN cord-022526-j9kg00qf 5685 8 Clostridium clostridium NN cord-022526-j9kg00qf 5685 9 difficile difficile NN cord-022526-j9kg00qf 5685 10 colonisation colonisation NN cord-022526-j9kg00qf 5685 11 of of IN cord-022526-j9kg00qf 5685 12 the the DT cord-022526-j9kg00qf 5685 13 gut gut NN cord-022526-j9kg00qf 5685 14 Studies Studies NNPS cord-022526-j9kg00qf 5685 15 on on IN cord-022526-j9kg00qf 5685 16 experimental experimental JJ cord-022526-j9kg00qf 5685 17 enteric enteric JJ cord-022526-j9kg00qf 5685 18 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5685 19 in in IN cord-022526-j9kg00qf 5685 20 ponies pony NNS cord-022526-j9kg00qf 5685 21 Physiology Physiology NNP cord-022526-j9kg00qf 5685 22 of of IN cord-022526-j9kg00qf 5685 23 diarrhea diarrhea NN cord-022526-j9kg00qf 5685 24 : : : cord-022526-j9kg00qf 5685 25 large large JJ cord-022526-j9kg00qf 5685 26 intestine intestine NN cord-022526-j9kg00qf 5686 1 Impaired impaired JJ cord-022526-j9kg00qf 5686 2 colonic colonic JJ cord-022526-j9kg00qf 5686 3 fermentation fermentation NN cord-022526-j9kg00qf 5686 4 of of IN cord-022526-j9kg00qf 5686 5 carbohydrate carbohydrate NN cord-022526-j9kg00qf 5686 6 after after IN cord-022526-j9kg00qf 5686 7 ampicillin ampicillin NN cord-022526-j9kg00qf 5687 1 The the DT cord-022526-j9kg00qf 5687 2 relationship relationship NN cord-022526-j9kg00qf 5687 3 of of IN cord-022526-j9kg00qf 5687 4 absorption absorption NN cord-022526-j9kg00qf 5687 5 characteristics characteristic NNS cord-022526-j9kg00qf 5687 6 and and CC cord-022526-j9kg00qf 5687 7 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5687 8 side side NN cord-022526-j9kg00qf 5687 9 effects effect NNS cord-022526-j9kg00qf 5687 10 of of IN cord-022526-j9kg00qf 5687 11 oral oral JJ cord-022526-j9kg00qf 5687 12 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5687 13 agents agent NNS cord-022526-j9kg00qf 5687 14 Prokinetic prokinetic JJ cord-022526-j9kg00qf 5687 15 effects effect NNS cord-022526-j9kg00qf 5687 16 of of IN cord-022526-j9kg00qf 5687 17 erythromycin erythromycin NN cord-022526-j9kg00qf 5687 18 on on IN cord-022526-j9kg00qf 5687 19 the the DT cord-022526-j9kg00qf 5687 20 ileum ileum NN cord-022526-j9kg00qf 5687 21 , , , cord-022526-j9kg00qf 5687 22 cecum cecum NN cord-022526-j9kg00qf 5687 23 , , , cord-022526-j9kg00qf 5687 24 and and CC cord-022526-j9kg00qf 5687 25 pelvic pelvic JJ cord-022526-j9kg00qf 5687 26 flexure flexure NN cord-022526-j9kg00qf 5687 27 of of IN cord-022526-j9kg00qf 5687 28 horses horse NNS cord-022526-j9kg00qf 5687 29 during during IN cord-022526-j9kg00qf 5687 30 the the DT cord-022526-j9kg00qf 5687 31 postoperative postoperative JJ cord-022526-j9kg00qf 5687 32 period period NN cord-022526-j9kg00qf 5687 33 Hypovolemic Hypovolemic NNP cord-022526-j9kg00qf 5687 34 hyponatremia hyponatremia NN cord-022526-j9kg00qf 5687 35 and and CC cord-022526-j9kg00qf 5687 36 signs sign NNS cord-022526-j9kg00qf 5687 37 of of IN cord-022526-j9kg00qf 5687 38 neurologic neurologic JJ cord-022526-j9kg00qf 5687 39 disease disease NN cord-022526-j9kg00qf 5687 40 associated associate VBN cord-022526-j9kg00qf 5687 41 with with IN cord-022526-j9kg00qf 5687 42 diarrhea diarrhea NN cord-022526-j9kg00qf 5687 43 in in IN cord-022526-j9kg00qf 5687 44 a a DT cord-022526-j9kg00qf 5687 45 foal foal NN cord-022526-j9kg00qf 5687 46 Toxicology Toxicology NNP cord-022526-j9kg00qf 5687 47 of of IN cord-022526-j9kg00qf 5687 48 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5687 49 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5687 50 drugs drug NNS cord-022526-j9kg00qf 5687 51 Colitis colitis NN cord-022526-j9kg00qf 5687 52 induced induce VBN cord-022526-j9kg00qf 5687 53 by by IN cord-022526-j9kg00qf 5687 54 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5687 55 anti anti JJ cord-022526-j9kg00qf 5687 56 - - JJ cord-022526-j9kg00qf 5687 57 inflammatory inflammatory JJ cord-022526-j9kg00qf 5687 58 drugs drug NNS cord-022526-j9kg00qf 5687 59 : : : cord-022526-j9kg00qf 5687 60 report report VB cord-022526-j9kg00qf 5687 61 of of IN cord-022526-j9kg00qf 5687 62 four four CD cord-022526-j9kg00qf 5687 63 cases case NNS cord-022526-j9kg00qf 5687 64 and and CC cord-022526-j9kg00qf 5687 65 review review NN cord-022526-j9kg00qf 5687 66 of of IN cord-022526-j9kg00qf 5687 67 the the DT cord-022526-j9kg00qf 5687 68 literature literature NN cord-022526-j9kg00qf 5688 1 The the DT cord-022526-j9kg00qf 5688 2 effects effect NNS cord-022526-j9kg00qf 5688 3 of of IN cord-022526-j9kg00qf 5688 4 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 5688 5 on on IN cord-022526-j9kg00qf 5688 6 the the DT cord-022526-j9kg00qf 5688 7 intestinal intestinal JJ cord-022526-j9kg00qf 5688 8 mucosa mucosa NN cord-022526-j9kg00qf 5688 9 of of IN cord-022526-j9kg00qf 5688 10 the the DT cord-022526-j9kg00qf 5688 11 horse horse NN cord-022526-j9kg00qf 5688 12 : : : cord-022526-j9kg00qf 5688 13 a a DT cord-022526-j9kg00qf 5688 14 morphological morphological JJ cord-022526-j9kg00qf 5688 15 , , , cord-022526-j9kg00qf 5688 16 ultrastructural ultrastructural JJ cord-022526-j9kg00qf 5688 17 and and CC cord-022526-j9kg00qf 5688 18 biochemical biochemical JJ cord-022526-j9kg00qf 5688 19 study study NN cord-022526-j9kg00qf 5688 20 Experimentally experimentally RB cord-022526-j9kg00qf 5688 21 induced induce VBD cord-022526-j9kg00qf 5688 22 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 5688 23 toxicosis toxicosis NN cord-022526-j9kg00qf 5688 24 in in IN cord-022526-j9kg00qf 5688 25 ponies pony NNS cord-022526-j9kg00qf 5688 26 : : : cord-022526-j9kg00qf 5688 27 description description NN cord-022526-j9kg00qf 5688 28 of of IN cord-022526-j9kg00qf 5688 29 the the DT cord-022526-j9kg00qf 5688 30 syndrome syndrome NN cord-022526-j9kg00qf 5688 31 and and CC cord-022526-j9kg00qf 5688 32 its -PRON- PRP$ cord-022526-j9kg00qf 5688 33 prevention prevention NN cord-022526-j9kg00qf 5688 34 with with IN cord-022526-j9kg00qf 5688 35 synthetic synthetic JJ cord-022526-j9kg00qf 5688 36 prostaglandin prostaglandin NN cord-022526-j9kg00qf 5688 37 E2 E2 NNP cord-022526-j9kg00qf 5688 38 Phenylbutazone Phenylbutazone NNP cord-022526-j9kg00qf 5688 39 toxicosis toxicosis NN cord-022526-j9kg00qf 5688 40 in in IN cord-022526-j9kg00qf 5688 41 the the DT cord-022526-j9kg00qf 5688 42 horse horse NN cord-022526-j9kg00qf 5688 43 : : : cord-022526-j9kg00qf 5688 44 a a DT cord-022526-j9kg00qf 5688 45 clinical clinical JJ cord-022526-j9kg00qf 5688 46 study study NN cord-022526-j9kg00qf 5688 47 Ulceration ulceration NN cord-022526-j9kg00qf 5688 48 and and CC cord-022526-j9kg00qf 5688 49 stricture stricture NN cord-022526-j9kg00qf 5688 50 of of IN cord-022526-j9kg00qf 5688 51 the the DT cord-022526-j9kg00qf 5688 52 right right JJ cord-022526-j9kg00qf 5688 53 dorsal dorsal JJ cord-022526-j9kg00qf 5688 54 colon colon NN cord-022526-j9kg00qf 5688 55 after after IN cord-022526-j9kg00qf 5688 56 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 5688 57 administration administration NNP cord-022526-j9kg00qf 5688 58 in in IN cord-022526-j9kg00qf 5688 59 four four CD cord-022526-j9kg00qf 5688 60 horses horse NNS cord-022526-j9kg00qf 5689 1 Phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 5689 2 toxicity toxicity NN cord-022526-j9kg00qf 5689 3 in in IN cord-022526-j9kg00qf 5689 4 a a DT cord-022526-j9kg00qf 5689 5 horse horse NN cord-022526-j9kg00qf 5689 6 Biochemical biochemical JJ cord-022526-j9kg00qf 5689 7 and and CC cord-022526-j9kg00qf 5689 8 haematological haematological JJ cord-022526-j9kg00qf 5689 9 effects effect NNS cord-022526-j9kg00qf 5689 10 of of IN cord-022526-j9kg00qf 5689 11 phenylbutazone phenylbutazone NN cord-022526-j9kg00qf 5689 12 in in IN cord-022526-j9kg00qf 5689 13 horses horse NNS cord-022526-j9kg00qf 5689 14 Medical medical JJ cord-022526-j9kg00qf 5689 15 management management NN cord-022526-j9kg00qf 5689 16 of of IN cord-022526-j9kg00qf 5689 17 right right JJ cord-022526-j9kg00qf 5689 18 dorsal dorsal JJ cord-022526-j9kg00qf 5689 19 colitis colitis NN cord-022526-j9kg00qf 5689 20 in in IN cord-022526-j9kg00qf 5689 21 5 5 CD cord-022526-j9kg00qf 5689 22 horses horse NNS cord-022526-j9kg00qf 5689 23 : : : cord-022526-j9kg00qf 5689 24 a a DT cord-022526-j9kg00qf 5689 25 retrospective retrospective JJ cord-022526-j9kg00qf 5689 26 study study NN cord-022526-j9kg00qf 5689 27 Mechanisms mechanism NNS cord-022526-j9kg00qf 5689 28 of of IN cord-022526-j9kg00qf 5689 29 intestinal intestinal JJ cord-022526-j9kg00qf 5689 30 mucosal mucosal NN cord-022526-j9kg00qf 5689 31 repair repair NN cord-022526-j9kg00qf 5689 32 Prostaglandins prostaglandin NNS cord-022526-j9kg00qf 5689 33 in in IN cord-022526-j9kg00qf 5689 34 the the DT cord-022526-j9kg00qf 5689 35 gut gut NN cord-022526-j9kg00qf 5689 36 and and CC cord-022526-j9kg00qf 5689 37 their -PRON- PRP$ cord-022526-j9kg00qf 5689 38 relationship relationship NN cord-022526-j9kg00qf 5689 39 to to IN cord-022526-j9kg00qf 5689 40 non non JJ cord-022526-j9kg00qf 5689 41 - - JJ cord-022526-j9kg00qf 5689 42 steroidal steroidal JJ cord-022526-j9kg00qf 5689 43 anti anti JJ cord-022526-j9kg00qf 5689 44 - - JJ cord-022526-j9kg00qf 5689 45 inflammatory inflammatory JJ cord-022526-j9kg00qf 5689 46 drugs drug NNS cord-022526-j9kg00qf 5690 1 The the DT cord-022526-j9kg00qf 5690 2 future future NN cord-022526-j9kg00qf 5690 3 of of IN cord-022526-j9kg00qf 5690 4 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5690 5 therapy therapy NN cord-022526-j9kg00qf 5691 1 The the DT cord-022526-j9kg00qf 5691 2 role role NN cord-022526-j9kg00qf 5691 3 of of IN cord-022526-j9kg00qf 5691 4 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 5691 5 inhibitors inhibitor NNS cord-022526-j9kg00qf 5691 6 in in IN cord-022526-j9kg00qf 5691 7 repair repair NN cord-022526-j9kg00qf 5691 8 of of IN cord-022526-j9kg00qf 5691 9 ischaemic ischaemic NN cord-022526-j9kg00qf 5691 10 - - HYPH cord-022526-j9kg00qf 5691 11 injured injure VBN cord-022526-j9kg00qf 5691 12 jejunal jejunal JJ cord-022526-j9kg00qf 5691 13 mucosa mucosa NNP cord-022526-j9kg00qf 5691 14 in in IN cord-022526-j9kg00qf 5691 15 the the DT cord-022526-j9kg00qf 5691 16 horse horse NN cord-022526-j9kg00qf 5691 17 Mechanisms Mechanisms NNPS cord-022526-j9kg00qf 5691 18 of of IN cord-022526-j9kg00qf 5691 19 acute acute JJ cord-022526-j9kg00qf 5691 20 and and CC cord-022526-j9kg00qf 5691 21 chronic chronic JJ cord-022526-j9kg00qf 5691 22 intestinal intestinal JJ cord-022526-j9kg00qf 5691 23 inflammation inflammation NN cord-022526-j9kg00qf 5691 24 induced induce VBN cord-022526-j9kg00qf 5691 25 by by IN cord-022526-j9kg00qf 5691 26 indomethacin indomethacin NN cord-022526-j9kg00qf 5691 27 Mechanisms Mechanisms NNPS cord-022526-j9kg00qf 5691 28 of of IN cord-022526-j9kg00qf 5691 29 NSAID NSAID NNP cord-022526-j9kg00qf 5691 30 - - HYPH cord-022526-j9kg00qf 5691 31 induced induce VBN cord-022526-j9kg00qf 5691 32 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5691 33 injury injury NN cord-022526-j9kg00qf 5691 34 defined define VBN cord-022526-j9kg00qf 5691 35 using use VBG cord-022526-j9kg00qf 5691 36 mutant mutant JJ cord-022526-j9kg00qf 5691 37 mice mouse NNS cord-022526-j9kg00qf 5691 38 Pathogenesis Pathogenesis NNP cord-022526-j9kg00qf 5691 39 of of IN cord-022526-j9kg00qf 5691 40 NSAID NSAID NNP cord-022526-j9kg00qf 5691 41 gastropathy gastropathy NNP cord-022526-j9kg00qf 5691 42 : : : cord-022526-j9kg00qf 5691 43 are be VBP cord-022526-j9kg00qf 5691 44 neutrophils neutrophil NNS cord-022526-j9kg00qf 5691 45 the the DT cord-022526-j9kg00qf 5691 46 culprits culprit NNS cord-022526-j9kg00qf 5691 47 ? ? . cord-022526-j9kg00qf 5692 1 ICAM-1 ICAM-1 NNP cord-022526-j9kg00qf 5692 2 and and CC cord-022526-j9kg00qf 5692 3 P p NN cord-022526-j9kg00qf 5692 4 - - HYPH cord-022526-j9kg00qf 5692 5 selectin selectin JJ cord-022526-j9kg00qf 5692 6 expression expression NN cord-022526-j9kg00qf 5692 7 in in IN cord-022526-j9kg00qf 5692 8 a a DT cord-022526-j9kg00qf 5692 9 model model NN cord-022526-j9kg00qf 5692 10 of of IN cord-022526-j9kg00qf 5692 11 NSAID NSAID NNP cord-022526-j9kg00qf 5692 12 - - HYPH cord-022526-j9kg00qf 5692 13 induced induce VBN cord-022526-j9kg00qf 5692 14 gastropathy gastropathy NNP cord-022526-j9kg00qf 5692 15 Gastric gastric JJ cord-022526-j9kg00qf 5692 16 ulceration ulceration NN cord-022526-j9kg00qf 5692 17 induced induce VBN cord-022526-j9kg00qf 5692 18 by by IN cord-022526-j9kg00qf 5692 19 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5692 20 anti anti JJ cord-022526-j9kg00qf 5692 21 - - JJ cord-022526-j9kg00qf 5692 22 inflammatory inflammatory JJ cord-022526-j9kg00qf 5692 23 drugs drug NNS cord-022526-j9kg00qf 5692 24 is be VBZ cord-022526-j9kg00qf 5692 25 a a DT cord-022526-j9kg00qf 5692 26 neutrophil neutrophil NN cord-022526-j9kg00qf 5692 27 - - HYPH cord-022526-j9kg00qf 5692 28 dependent dependent JJ cord-022526-j9kg00qf 5692 29 process process NN cord-022526-j9kg00qf 5692 30 The the DT cord-022526-j9kg00qf 5692 31 recognition recognition NN cord-022526-j9kg00qf 5692 32 and and CC cord-022526-j9kg00qf 5692 33 medical medical JJ cord-022526-j9kg00qf 5692 34 management management NN cord-022526-j9kg00qf 5692 35 of of IN cord-022526-j9kg00qf 5692 36 right right JJ cord-022526-j9kg00qf 5692 37 dorsal dorsal JJ cord-022526-j9kg00qf 5692 38 colitis colitis NN cord-022526-j9kg00qf 5692 39 in in IN cord-022526-j9kg00qf 5692 40 horses horse NNS cord-022526-j9kg00qf 5693 1 The the DT cord-022526-j9kg00qf 5693 2 application application NN cord-022526-j9kg00qf 5693 3 of of IN cord-022526-j9kg00qf 5693 4 technetium-99 technetium-99 NN cord-022526-j9kg00qf 5693 5 m m NNP cord-022526-j9kg00qf 5693 6 hexamethylpropyleneamine hexamethylpropyleneamine NNP cord-022526-j9kg00qf 5693 7 oxime oxime NN cord-022526-j9kg00qf 5694 1 ( ( -LRB- cord-022526-j9kg00qf 5694 2 99mTc 99mtc NN cord-022526-j9kg00qf 5694 3 - - HYPH cord-022526-j9kg00qf 5694 4 HMPAO HMPAO NNP cord-022526-j9kg00qf 5694 5 ) ) -RRB- cord-022526-j9kg00qf 5694 6 labeled label VBD cord-022526-j9kg00qf 5694 7 white white JJ cord-022526-j9kg00qf 5694 8 blood blood NN cord-022526-j9kg00qf 5694 9 cells cell NNS cord-022526-j9kg00qf 5694 10 for for IN cord-022526-j9kg00qf 5694 11 the the DT cord-022526-j9kg00qf 5694 12 diagnosis diagnosis NN cord-022526-j9kg00qf 5694 13 of of IN cord-022526-j9kg00qf 5694 14 right right JJ cord-022526-j9kg00qf 5694 15 dorsal dorsal JJ cord-022526-j9kg00qf 5694 16 ulcerative ulcerative JJ cord-022526-j9kg00qf 5694 17 colitis colitis NN cord-022526-j9kg00qf 5694 18 in in IN cord-022526-j9kg00qf 5694 19 two two CD cord-022526-j9kg00qf 5694 20 horses horse NNS cord-022526-j9kg00qf 5694 21 Cantharidin Cantharidin NNP cord-022526-j9kg00qf 5694 22 toxicosis toxicosis NN cord-022526-j9kg00qf 5694 23 in in IN cord-022526-j9kg00qf 5694 24 horses horse NNS cord-022526-j9kg00qf 5695 1 Experimental experimental JJ cord-022526-j9kg00qf 5695 2 cantharidiasis cantharidiasis NN cord-022526-j9kg00qf 5695 3 in in IN cord-022526-j9kg00qf 5695 4 the the DT cord-022526-j9kg00qf 5695 5 horse horse NN cord-022526-j9kg00qf 5695 6 Pathology Pathology NNP cord-022526-j9kg00qf 5695 7 of of IN cord-022526-j9kg00qf 5695 8 blister blister NN cord-022526-j9kg00qf 5695 9 beetle beetle NN cord-022526-j9kg00qf 5695 10 ( ( -LRB- cord-022526-j9kg00qf 5695 11 Epicauta epicauta NN cord-022526-j9kg00qf 5695 12 ) ) -RRB- cord-022526-j9kg00qf 5695 13 poisoning poisoning NN cord-022526-j9kg00qf 5695 14 in in IN cord-022526-j9kg00qf 5695 15 horses horse NNS cord-022526-j9kg00qf 5695 16 Etiologic Etiologic NNP cord-022526-j9kg00qf 5695 17 agents agent NNS cord-022526-j9kg00qf 5695 18 , , , cord-022526-j9kg00qf 5695 19 incidence incidence NN cord-022526-j9kg00qf 5695 20 , , , cord-022526-j9kg00qf 5695 21 and and CC cord-022526-j9kg00qf 5695 22 improved improve VBN cord-022526-j9kg00qf 5695 23 diagnostic diagnostic JJ cord-022526-j9kg00qf 5695 24 methods method NNS cord-022526-j9kg00qf 5695 25 of of IN cord-022526-j9kg00qf 5695 26 cantharidin cantharidin JJ cord-022526-j9kg00qf 5695 27 toxicosis toxicosis NN cord-022526-j9kg00qf 5695 28 in in IN cord-022526-j9kg00qf 5695 29 horses horse NNS cord-022526-j9kg00qf 5695 30 Clinical clinical JJ cord-022526-j9kg00qf 5695 31 features feature NNS cord-022526-j9kg00qf 5695 32 of of IN cord-022526-j9kg00qf 5695 33 blister blister NN cord-022526-j9kg00qf 5695 34 beetle beetle NN cord-022526-j9kg00qf 5695 35 poisoning poisoning NN cord-022526-j9kg00qf 5695 36 in in IN cord-022526-j9kg00qf 5695 37 equids equid NNS cord-022526-j9kg00qf 5695 38 : : : cord-022526-j9kg00qf 5695 39 70 70 CD cord-022526-j9kg00qf 5695 40 cases case NNS cord-022526-j9kg00qf 5695 41 Clinical clinical JJ cord-022526-j9kg00qf 5695 42 and and CC cord-022526-j9kg00qf 5695 43 diagnostic diagnostic JJ cord-022526-j9kg00qf 5695 44 veterinary veterinary JJ cord-022526-j9kg00qf 5695 45 toxicology toxicology NN cord-022526-j9kg00qf 5695 46 Environmental environmental JJ cord-022526-j9kg00qf 5695 47 biochemistry biochemistry NN cord-022526-j9kg00qf 5695 48 of of IN cord-022526-j9kg00qf 5695 49 arsenic arsenic NN cord-022526-j9kg00qf 5695 50 Trace trace NN cord-022526-j9kg00qf 5695 51 metal metal NN cord-022526-j9kg00qf 5695 52 poisoning poisoning NN cord-022526-j9kg00qf 5695 53 Gee gee NN cord-022526-j9kg00qf 5695 54 , , , cord-022526-j9kg00qf 5695 55 honey honey NN cord-022526-j9kg00qf 5696 1 , , , cord-022526-j9kg00qf 5696 2 why why WRB cord-022526-j9kg00qf 5696 3 does do VBZ cord-022526-j9kg00qf 5696 4 the the DT cord-022526-j9kg00qf 5696 5 iced iced JJ cord-022526-j9kg00qf 5696 6 tea tea NN cord-022526-j9kg00qf 5696 7 have have VBP cord-022526-j9kg00qf 5696 8 a a DT cord-022526-j9kg00qf 5696 9 garlic garlic NN cord-022526-j9kg00qf 5696 10 taste taste NN cord-022526-j9kg00qf 5696 11 ? ? . cord-022526-j9kg00qf 5697 1 Arsenic arsenic NN cord-022526-j9kg00qf 5697 2 intoxication intoxication NN cord-022526-j9kg00qf 5698 1 Acute acute JJ cord-022526-j9kg00qf 5698 2 diarrheal diarrheal JJ cord-022526-j9kg00qf 5698 3 disease disease NN cord-022526-j9kg00qf 5698 4 in in IN cord-022526-j9kg00qf 5698 5 the the DT cord-022526-j9kg00qf 5698 6 horse horse NN cord-022526-j9kg00qf 5699 1 The the DT cord-022526-j9kg00qf 5699 2 mucosal mucosal JJ cord-022526-j9kg00qf 5699 3 barrier barrier NN cord-022526-j9kg00qf 5699 4 , , , cord-022526-j9kg00qf 5699 5 IgE ige NN cord-022526-j9kg00qf 5699 6 - - HYPH cord-022526-j9kg00qf 5699 7 mediated mediate VBN cord-022526-j9kg00qf 5699 8 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5699 9 events event NNS cord-022526-j9kg00qf 5699 10 , , , cord-022526-j9kg00qf 5699 11 and and CC cord-022526-j9kg00qf 5699 12 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5699 13 gastroenteritis gastroenteritis NN cord-022526-j9kg00qf 5699 14 IgE ige NN cord-022526-j9kg00qf 5699 15 - - HYPH cord-022526-j9kg00qf 5699 16 mediated mediate VBN cord-022526-j9kg00qf 5699 17 ( ( -LRB- cord-022526-j9kg00qf 5699 18 and and CC cord-022526-j9kg00qf 5699 19 food food NN cord-022526-j9kg00qf 5699 20 - - HYPH cord-022526-j9kg00qf 5699 21 induced induce VBN cord-022526-j9kg00qf 5699 22 ) ) -RRB- cord-022526-j9kg00qf 5699 23 intestinal intestinal JJ cord-022526-j9kg00qf 5699 24 disease disease NN cord-022526-j9kg00qf 5699 25 Induction induction NN cord-022526-j9kg00qf 5699 26 of of IN cord-022526-j9kg00qf 5699 27 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 28 in in IN cord-022526-j9kg00qf 5699 29 mouse mouse NN cord-022526-j9kg00qf 5699 30 intestine intestine NN cord-022526-j9kg00qf 5699 31 by by IN cord-022526-j9kg00qf 5699 32 orally orally RB cord-022526-j9kg00qf 5699 33 administered administer VBN cord-022526-j9kg00qf 5699 34 antigen antigen NN cord-022526-j9kg00qf 5699 35 and and CC cord-022526-j9kg00qf 5699 36 its -PRON- PRP$ cord-022526-j9kg00qf 5699 37 prevention prevention NN cord-022526-j9kg00qf 5699 38 with with IN cord-022526-j9kg00qf 5699 39 soluble soluble JJ cord-022526-j9kg00qf 5699 40 high high JJ cord-022526-j9kg00qf 5699 41 affinity affinity NN cord-022526-j9kg00qf 5699 42 receptor receptor NN cord-022526-j9kg00qf 5699 43 for for IN cord-022526-j9kg00qf 5699 44 IgE IgE NNP cord-022526-j9kg00qf 5699 45 Vaccine Vaccine NNP cord-022526-j9kg00qf 5699 46 - - HYPH cord-022526-j9kg00qf 5699 47 associated associate VBN cord-022526-j9kg00qf 5699 48 anaphylactic anaphylactic JJ cord-022526-j9kg00qf 5699 49 - - HYPH cord-022526-j9kg00qf 5699 50 like like JJ cord-022526-j9kg00qf 5699 51 reaction reaction NN cord-022526-j9kg00qf 5699 52 in in IN cord-022526-j9kg00qf 5699 53 a a DT cord-022526-j9kg00qf 5699 54 horse horse NN cord-022526-j9kg00qf 5699 55 Equine equine JJ cord-022526-j9kg00qf 5699 56 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 57 Equine equine JJ cord-022526-j9kg00qf 5699 58 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 59 Pathologic pathologic JJ cord-022526-j9kg00qf 5699 60 changes change NNS cord-022526-j9kg00qf 5699 61 in in IN cord-022526-j9kg00qf 5699 62 experimental experimental JJ cord-022526-j9kg00qf 5699 63 equine equine JJ cord-022526-j9kg00qf 5699 64 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 65 Role role NN cord-022526-j9kg00qf 5699 66 of of IN cord-022526-j9kg00qf 5699 67 intestinal intestinal JJ cord-022526-j9kg00qf 5699 68 mast mast NN cord-022526-j9kg00qf 5699 69 cells cell NNS cord-022526-j9kg00qf 5699 70 in in IN cord-022526-j9kg00qf 5699 71 modulating modulate VBG cord-022526-j9kg00qf 5699 72 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5699 73 pathophysiology pathophysiology NN cord-022526-j9kg00qf 5699 74 Role role NN cord-022526-j9kg00qf 5699 75 of of IN cord-022526-j9kg00qf 5699 76 5-hydroxytryptamine 5-hydroxytryptamine CD cord-022526-j9kg00qf 5699 77 in in IN cord-022526-j9kg00qf 5699 78 intestinal intestinal JJ cord-022526-j9kg00qf 5699 79 water water NN cord-022526-j9kg00qf 5699 80 and and CC cord-022526-j9kg00qf 5699 81 electrolyte electrolyte JJ cord-022526-j9kg00qf 5699 82 movement movement NN cord-022526-j9kg00qf 5699 83 during during IN cord-022526-j9kg00qf 5699 84 gut gut NN cord-022526-j9kg00qf 5699 85 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 86 Intestinal intestinal JJ cord-022526-j9kg00qf 5699 87 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 88 in in IN cord-022526-j9kg00qf 5699 89 the the DT cord-022526-j9kg00qf 5699 90 rat rat NN cord-022526-j9kg00qf 5699 91 : : : cord-022526-j9kg00qf 5699 92 mediators mediator NNS cord-022526-j9kg00qf 5699 93 responsible responsible JJ cord-022526-j9kg00qf 5699 94 for for IN cord-022526-j9kg00qf 5699 95 the the DT cord-022526-j9kg00qf 5699 96 ion ion NN cord-022526-j9kg00qf 5699 97 transport transport NN cord-022526-j9kg00qf 5699 98 abnormalities abnormality NNS cord-022526-j9kg00qf 5699 99 Motility motility NN cord-022526-j9kg00qf 5699 100 effects effect NNS cord-022526-j9kg00qf 5699 101 of of IN cord-022526-j9kg00qf 5699 102 intestinal intestinal JJ cord-022526-j9kg00qf 5699 103 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 104 in in IN cord-022526-j9kg00qf 5699 105 the the DT cord-022526-j9kg00qf 5699 106 rat rat NN cord-022526-j9kg00qf 5699 107 Intestinal intestinal JJ cord-022526-j9kg00qf 5699 108 anaphylaxis anaphylaxis NN cord-022526-j9kg00qf 5699 109 : : : cord-022526-j9kg00qf 5699 110 rapid rapid JJ cord-022526-j9kg00qf 5699 111 changes change NNS cord-022526-j9kg00qf 5699 112 in in IN cord-022526-j9kg00qf 5699 113 mucosal mucosal JJ cord-022526-j9kg00qf 5699 114 ion ion NN cord-022526-j9kg00qf 5699 115 transport transport NN cord-022526-j9kg00qf 5699 116 and and CC cord-022526-j9kg00qf 5699 117 morphology morphology NN cord-022526-j9kg00qf 5699 118 Exhaustion exhaustion NN cord-022526-j9kg00qf 5699 119 shock shock NN cord-022526-j9kg00qf 5699 120 in in IN cord-022526-j9kg00qf 5699 121 the the DT cord-022526-j9kg00qf 5699 122 horse horse NN cord-022526-j9kg00qf 5699 123 Lactic lactic JJ cord-022526-j9kg00qf 5699 124 acidosis acidosis NN cord-022526-j9kg00qf 5699 125 : : : cord-022526-j9kg00qf 5699 126 a a DT cord-022526-j9kg00qf 5699 127 factor factor NN cord-022526-j9kg00qf 5699 128 associated associate VBN cord-022526-j9kg00qf 5699 129 with with IN cord-022526-j9kg00qf 5699 130 equine equine JJ cord-022526-j9kg00qf 5699 131 laminitis laminitis NN cord-022526-j9kg00qf 5699 132 Changes change NNS cord-022526-j9kg00qf 5699 133 in in IN cord-022526-j9kg00qf 5699 134 the the DT cord-022526-j9kg00qf 5699 135 caecal caecal JJ cord-022526-j9kg00qf 5699 136 flora flora NNS cord-022526-j9kg00qf 5699 137 associated associate VBN cord-022526-j9kg00qf 5699 138 with with IN cord-022526-j9kg00qf 5699 139 the the DT cord-022526-j9kg00qf 5699 140 onset onset NN cord-022526-j9kg00qf 5699 141 of of IN cord-022526-j9kg00qf 5699 142 laminitis laminitis NN cord-022526-j9kg00qf 5699 143 Intracecal Intracecal NNP cord-022526-j9kg00qf 5699 144 endotoxin endotoxin NN cord-022526-j9kg00qf 5699 145 and and CC cord-022526-j9kg00qf 5699 146 lactate lactate NN cord-022526-j9kg00qf 5699 147 during during IN cord-022526-j9kg00qf 5699 148 the the DT cord-022526-j9kg00qf 5699 149 onset onset NN cord-022526-j9kg00qf 5699 150 of of IN cord-022526-j9kg00qf 5699 151 equine equine JJ cord-022526-j9kg00qf 5699 152 laminitis laminitis NN cord-022526-j9kg00qf 5699 153 : : : cord-022526-j9kg00qf 5699 154 a a DT cord-022526-j9kg00qf 5699 155 preliminary preliminary JJ cord-022526-j9kg00qf 5699 156 report report NN cord-022526-j9kg00qf 5699 157 Plasma plasma NN cord-022526-j9kg00qf 5699 158 endotoxin endotoxin NN cord-022526-j9kg00qf 5699 159 levels level NNS cord-022526-j9kg00qf 5699 160 in in IN cord-022526-j9kg00qf 5699 161 horses horse NNS cord-022526-j9kg00qf 5699 162 subjected subject VBN cord-022526-j9kg00qf 5699 163 to to IN cord-022526-j9kg00qf 5699 164 carbohydrate carbohydrate NN cord-022526-j9kg00qf 5699 165 induced induce VBN cord-022526-j9kg00qf 5699 166 laminitis laminitis NN cord-022526-j9kg00qf 5699 167 Surgical surgical JJ cord-022526-j9kg00qf 5699 168 treatment treatment NN cord-022526-j9kg00qf 5699 169 of of IN cord-022526-j9kg00qf 5699 170 sand sand NN cord-022526-j9kg00qf 5699 171 colic colic NN cord-022526-j9kg00qf 5699 172 : : : cord-022526-j9kg00qf 5699 173 results result NNS cord-022526-j9kg00qf 5699 174 in in IN cord-022526-j9kg00qf 5699 175 40 40 CD cord-022526-j9kg00qf 5699 176 horses horse NNS cord-022526-j9kg00qf 5699 177 Diarrhea diarrhea VBP cord-022526-j9kg00qf 5699 178 associated associate VBN cord-022526-j9kg00qf 5699 179 with with IN cord-022526-j9kg00qf 5699 180 sand sand NN cord-022526-j9kg00qf 5699 181 in in IN cord-022526-j9kg00qf 5699 182 the the DT cord-022526-j9kg00qf 5699 183 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5699 184 tract tract NN cord-022526-j9kg00qf 5699 185 of of IN cord-022526-j9kg00qf 5699 186 horses horse NNS cord-022526-j9kg00qf 5699 187 Sand sand NN cord-022526-j9kg00qf 5699 188 - - HYPH cord-022526-j9kg00qf 5699 189 induced induce VBN cord-022526-j9kg00qf 5699 190 diarrhea diarrhea NN cord-022526-j9kg00qf 5699 191 in in IN cord-022526-j9kg00qf 5699 192 a a DT cord-022526-j9kg00qf 5699 193 foal foal NN cord-022526-j9kg00qf 5699 194 Abdominal abdominal JJ cord-022526-j9kg00qf 5699 195 auscultation auscultation NN cord-022526-j9kg00qf 5699 196 in in IN cord-022526-j9kg00qf 5699 197 the the DT cord-022526-j9kg00qf 5699 198 detection detection NN cord-022526-j9kg00qf 5699 199 of of IN cord-022526-j9kg00qf 5699 200 experimentally experimentally RB cord-022526-j9kg00qf 5699 201 induced induce VBN cord-022526-j9kg00qf 5699 202 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5699 203 sand sand NN cord-022526-j9kg00qf 5699 204 accumulation accumulation NN cord-022526-j9kg00qf 5699 205 Nasogastric nasogastric NN cord-022526-j9kg00qf 5699 206 electrolyte electrolyte JJ cord-022526-j9kg00qf 5699 207 replacement replacement NN cord-022526-j9kg00qf 5699 208 in in IN cord-022526-j9kg00qf 5699 209 horses horse NNS cord-022526-j9kg00qf 5699 210 Acute acute JJ cord-022526-j9kg00qf 5699 211 colitis colitis NN cord-022526-j9kg00qf 5699 212 in in IN cord-022526-j9kg00qf 5699 213 horses horse NNS cord-022526-j9kg00qf 5699 214 . . . cord-022526-j9kg00qf 5700 1 2 2 LS cord-022526-j9kg00qf 5700 2 . . . cord-022526-j9kg00qf 5701 1 Initial initial JJ cord-022526-j9kg00qf 5701 2 management management NN cord-022526-j9kg00qf 5701 3 Effect effect NN cord-022526-j9kg00qf 5701 4 of of IN cord-022526-j9kg00qf 5701 5 hydroxyethyl hydroxyethyl NN cord-022526-j9kg00qf 5701 6 starch starch NN cord-022526-j9kg00qf 5701 7 infusion infusion NN cord-022526-j9kg00qf 5701 8 on on IN cord-022526-j9kg00qf 5701 9 colloid colloid NN cord-022526-j9kg00qf 5701 10 oncotic oncotic JJ cord-022526-j9kg00qf 5701 11 pressure pressure NN cord-022526-j9kg00qf 5701 12 in in IN cord-022526-j9kg00qf 5701 13 hypoproteinemic hypoproteinemic NNP cord-022526-j9kg00qf 5701 14 horses horse NNS cord-022526-j9kg00qf 5701 15 Oncotic Oncotic NNP cord-022526-j9kg00qf 5701 16 , , , cord-022526-j9kg00qf 5701 17 hemodilutional hemodilutional NN cord-022526-j9kg00qf 5701 18 , , , cord-022526-j9kg00qf 5701 19 and and CC cord-022526-j9kg00qf 5701 20 hemostatic hemostatic JJ cord-022526-j9kg00qf 5701 21 effects effect NNS cord-022526-j9kg00qf 5701 22 of of IN cord-022526-j9kg00qf 5701 23 isotonic isotonic JJ cord-022526-j9kg00qf 5701 24 saline saline NN cord-022526-j9kg00qf 5701 25 and and CC cord-022526-j9kg00qf 5701 26 hydroxyethyl hydroxyethyl NN cord-022526-j9kg00qf 5701 27 starch starch NN cord-022526-j9kg00qf 5701 28 solutions solution NNS cord-022526-j9kg00qf 5701 29 in in IN cord-022526-j9kg00qf 5701 30 clinically clinically RB cord-022526-j9kg00qf 5701 31 normal normal JJ cord-022526-j9kg00qf 5701 32 ponies pony NNS cord-022526-j9kg00qf 5701 33 Colloid Colloid NNP cord-022526-j9kg00qf 5701 34 volume volume NN cord-022526-j9kg00qf 5701 35 expanders expander NNS cord-022526-j9kg00qf 5701 36 : : : cord-022526-j9kg00qf 5701 37 problems problem NNS cord-022526-j9kg00qf 5701 38 , , , cord-022526-j9kg00qf 5701 39 pitfalls pitfall NNS cord-022526-j9kg00qf 5701 40 and and CC cord-022526-j9kg00qf 5701 41 possibilities possibility NNS cord-022526-j9kg00qf 5701 42 Immunity immunity NN cord-022526-j9kg00qf 5701 43 targeting target VBG cord-022526-j9kg00qf 5701 44 common common JJ cord-022526-j9kg00qf 5701 45 core core NN cord-022526-j9kg00qf 5701 46 antigens antigen NNS cord-022526-j9kg00qf 5701 47 of of IN cord-022526-j9kg00qf 5701 48 gram gram NN cord-022526-j9kg00qf 5701 49 - - HYPH cord-022526-j9kg00qf 5701 50 negative negative JJ cord-022526-j9kg00qf 5701 51 bacteria bacteria NNS cord-022526-j9kg00qf 5701 52 Protection protection NN cord-022526-j9kg00qf 5701 53 against against IN cord-022526-j9kg00qf 5701 54 clinical clinical JJ cord-022526-j9kg00qf 5701 55 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5701 56 in in IN cord-022526-j9kg00qf 5701 57 horses horse NNS cord-022526-j9kg00qf 5701 58 by by IN cord-022526-j9kg00qf 5701 59 using use VBG cord-022526-j9kg00qf 5701 60 plasma plasma NN cord-022526-j9kg00qf 5701 61 containing contain VBG cord-022526-j9kg00qf 5701 62 antibody antibody NN cord-022526-j9kg00qf 5701 63 to to IN cord-022526-j9kg00qf 5701 64 an an DT cord-022526-j9kg00qf 5701 65 Rc Rc NNP cord-022526-j9kg00qf 5701 66 mutant mutant JJ cord-022526-j9kg00qf 5701 67 E. E. NNP cord-022526-j9kg00qf 5701 68 coli coli NNS cord-022526-j9kg00qf 5701 69 ( ( -LRB- cord-022526-j9kg00qf 5701 70 J5 J5 NNP cord-022526-j9kg00qf 5701 71 ) ) -RRB- cord-022526-j9kg00qf 5701 72 Enterotoxin Enterotoxin NNP cord-022526-j9kg00qf 5701 73 activity activity NN cord-022526-j9kg00qf 5701 74 of of IN cord-022526-j9kg00qf 5701 75 a a DT cord-022526-j9kg00qf 5701 76 Salmonella Salmonella NNP cord-022526-j9kg00qf 5701 77 typhimurium typhimurium NN cord-022526-j9kg00qf 5701 78 of of IN cord-022526-j9kg00qf 5701 79 equine equine JJ cord-022526-j9kg00qf 5701 80 origin origin NN cord-022526-j9kg00qf 5701 81 in in IN cord-022526-j9kg00qf 5701 82 vivo vivo NN cord-022526-j9kg00qf 5701 83 in in IN cord-022526-j9kg00qf 5701 84 rabbits rabbit NNS cord-022526-j9kg00qf 5701 85 and and CC cord-022526-j9kg00qf 5701 86 the the DT cord-022526-j9kg00qf 5701 87 effect effect NN cord-022526-j9kg00qf 5701 88 of of IN cord-022526-j9kg00qf 5701 89 Salmonella Salmonella NNP cord-022526-j9kg00qf 5701 90 culture culture NN cord-022526-j9kg00qf 5701 91 lysates lysate NNS cord-022526-j9kg00qf 5701 92 and and CC cord-022526-j9kg00qf 5701 93 cholera cholera NN cord-022526-j9kg00qf 5701 94 toxin toxin NN cord-022526-j9kg00qf 5701 95 on on IN cord-022526-j9kg00qf 5701 96 equine equine JJ cord-022526-j9kg00qf 5701 97 colonic colonic JJ cord-022526-j9kg00qf 5701 98 mucosa mucosa NN cord-022526-j9kg00qf 5701 99 in in IN cord-022526-j9kg00qf 5701 100 vitro vitro FW cord-022526-j9kg00qf 5701 101 Enterotoxin Enterotoxin NNP cord-022526-j9kg00qf 5701 102 - - HYPH cord-022526-j9kg00qf 5701 103 induced induce VBN cord-022526-j9kg00qf 5701 104 fluid fluid JJ cord-022526-j9kg00qf 5701 105 accumulation accumulation NN cord-022526-j9kg00qf 5701 106 during during IN cord-022526-j9kg00qf 5701 107 experimental experimental JJ cord-022526-j9kg00qf 5701 108 salmonellosis salmonellosis NN cord-022526-j9kg00qf 5701 109 and and CC cord-022526-j9kg00qf 5701 110 cholera cholera NN cord-022526-j9kg00qf 5701 111 : : : cord-022526-j9kg00qf 5701 112 involvement involvement NN cord-022526-j9kg00qf 5701 113 of of IN cord-022526-j9kg00qf 5701 114 prostaglandin prostaglandin JJ cord-022526-j9kg00qf 5701 115 synthesis synthesis NN cord-022526-j9kg00qf 5701 116 by by IN cord-022526-j9kg00qf 5701 117 intestinal intestinal JJ cord-022526-j9kg00qf 5701 118 cells cell NNS cord-022526-j9kg00qf 5701 119 NaCl nacl NN cord-022526-j9kg00qf 5701 120 transport transport NN cord-022526-j9kg00qf 5701 121 across across IN cord-022526-j9kg00qf 5701 122 equine equine JJ cord-022526-j9kg00qf 5701 123 proximal proximal JJ cord-022526-j9kg00qf 5701 124 colon colon NN cord-022526-j9kg00qf 5701 125 and and CC cord-022526-j9kg00qf 5701 126 the the DT cord-022526-j9kg00qf 5701 127 effect effect NN cord-022526-j9kg00qf 5701 128 of of IN cord-022526-j9kg00qf 5701 129 endogenous endogenous JJ cord-022526-j9kg00qf 5701 130 prostanoids prostanoid NNS cord-022526-j9kg00qf 5701 131 Nonsteroidal Nonsteroidal NNP cord-022526-j9kg00qf 5701 132 anti anti JJ cord-022526-j9kg00qf 5701 133 - - JJ cord-022526-j9kg00qf 5701 134 inflammatory inflammatory JJ cord-022526-j9kg00qf 5701 135 drugs drug NNS cord-022526-j9kg00qf 5701 136 activate activate VBP cord-022526-j9kg00qf 5701 137 quiescent quiescent JJ cord-022526-j9kg00qf 5701 138 inflammatory inflammatory JJ cord-022526-j9kg00qf 5701 139 bowel bowel NN cord-022526-j9kg00qf 5701 140 disease disease NN cord-022526-j9kg00qf 5702 1 Misoprostol Misoprostol NNP cord-022526-j9kg00qf 5702 2 provides provide VBZ cord-022526-j9kg00qf 5702 3 a a DT cord-022526-j9kg00qf 5702 4 colonic colonic JJ cord-022526-j9kg00qf 5702 5 mucosal mucosal JJ cord-022526-j9kg00qf 5702 6 protective protective JJ cord-022526-j9kg00qf 5702 7 effect effect NN cord-022526-j9kg00qf 5702 8 during during IN cord-022526-j9kg00qf 5702 9 acetic acetic JJ cord-022526-j9kg00qf 5702 10 acidinduced acidinduced JJ cord-022526-j9kg00qf 5702 11 colitis colitis NN cord-022526-j9kg00qf 5702 12 in in IN cord-022526-j9kg00qf 5702 13 rats rat NNS cord-022526-j9kg00qf 5703 1 Rationale rationale NN cord-022526-j9kg00qf 5703 2 for for IN cord-022526-j9kg00qf 5703 3 the the DT cord-022526-j9kg00qf 5703 4 luminal luminal JJ cord-022526-j9kg00qf 5703 5 provision provision NN cord-022526-j9kg00qf 5703 6 of of IN cord-022526-j9kg00qf 5703 7 butyrate butyrate NN cord-022526-j9kg00qf 5703 8 in in IN cord-022526-j9kg00qf 5703 9 intestinal intestinal JJ cord-022526-j9kg00qf 5703 10 diseases disease NNS cord-022526-j9kg00qf 5704 1 Pharmacokinetics pharmacokinetic NNS cord-022526-j9kg00qf 5704 2 and and CC cord-022526-j9kg00qf 5704 3 adverse adverse JJ cord-022526-j9kg00qf 5704 4 effects effect NNS cord-022526-j9kg00qf 5704 5 of of IN cord-022526-j9kg00qf 5704 6 butorphanol butorphanol NN cord-022526-j9kg00qf 5704 7 administered administer VBN cord-022526-j9kg00qf 5704 8 by by IN cord-022526-j9kg00qf 5704 9 single single JJ cord-022526-j9kg00qf 5704 10 intravenous intravenous JJ cord-022526-j9kg00qf 5704 11 injection injection NN cord-022526-j9kg00qf 5704 12 or or CC cord-022526-j9kg00qf 5704 13 continuous continuous JJ cord-022526-j9kg00qf 5704 14 intravenous intravenous JJ cord-022526-j9kg00qf 5704 15 infusion infusion NN cord-022526-j9kg00qf 5704 16 in in IN cord-022526-j9kg00qf 5704 17 horses horse NNS cord-022526-j9kg00qf 5705 1 Necrotizing necrotize VBG cord-022526-j9kg00qf 5705 2 mycotic mycotic JJ cord-022526-j9kg00qf 5705 3 vasculitis vasculitis NN cord-022526-j9kg00qf 5705 4 with with IN cord-022526-j9kg00qf 5705 5 cerebral cerebral JJ cord-022526-j9kg00qf 5705 6 infarction infarction NN cord-022526-j9kg00qf 5705 7 caused cause VBN cord-022526-j9kg00qf 5705 8 by by IN cord-022526-j9kg00qf 5705 9 Aspergillus Aspergillus NNP cord-022526-j9kg00qf 5705 10 niger niger NNP cord-022526-j9kg00qf 5705 11 in in IN cord-022526-j9kg00qf 5705 12 a a DT cord-022526-j9kg00qf 5705 13 horse horse NN cord-022526-j9kg00qf 5705 14 with with IN cord-022526-j9kg00qf 5705 15 acute acute JJ cord-022526-j9kg00qf 5705 16 typholocolitis typholocolitis JJ cord-022526-j9kg00qf 5705 17 Pulmonary pulmonary JJ cord-022526-j9kg00qf 5705 18 aspergillosis aspergillosis NN cord-022526-j9kg00qf 5705 19 in in IN cord-022526-j9kg00qf 5705 20 horses horse NNS cord-022526-j9kg00qf 5705 21 : : : cord-022526-j9kg00qf 5705 22 29 29 CD cord-022526-j9kg00qf 5705 23 cases case NNS cord-022526-j9kg00qf 5705 24 ( ( -LRB- cord-022526-j9kg00qf 5705 25 1974 1974 CD cord-022526-j9kg00qf 5705 26 - - SYM cord-022526-j9kg00qf 5705 27 1997 1997 CD cord-022526-j9kg00qf 5705 28 ) ) -RRB- cord-022526-j9kg00qf 5706 1 Effect effect NN cord-022526-j9kg00qf 5706 2 of of IN cord-022526-j9kg00qf 5706 3 antibiotics antibiotic NNS cord-022526-j9kg00qf 5706 4 on on IN cord-022526-j9kg00qf 5706 5 clinical clinical JJ cord-022526-j9kg00qf 5706 6 , , , cord-022526-j9kg00qf 5706 7 pathologic pathologic JJ cord-022526-j9kg00qf 5706 8 and and CC cord-022526-j9kg00qf 5706 9 immunologic immunologic JJ cord-022526-j9kg00qf 5706 10 responses response NNS cord-022526-j9kg00qf 5706 11 in in IN cord-022526-j9kg00qf 5706 12 murine murine JJ cord-022526-j9kg00qf 5706 13 Potomac Potomac NNP cord-022526-j9kg00qf 5706 14 horse horse NN cord-022526-j9kg00qf 5706 15 fever fever NN cord-022526-j9kg00qf 5706 16 : : : cord-022526-j9kg00qf 5706 17 protective protective JJ cord-022526-j9kg00qf 5706 18 effects effect NNS cord-022526-j9kg00qf 5706 19 of of IN cord-022526-j9kg00qf 5706 20 doxycycline doxycycline NN cord-022526-j9kg00qf 5706 21 Effect effect NN cord-022526-j9kg00qf 5706 22 of of IN cord-022526-j9kg00qf 5706 23 treatment treatment NN cord-022526-j9kg00qf 5706 24 with with IN cord-022526-j9kg00qf 5706 25 oxytetracycline oxytetracycline NN cord-022526-j9kg00qf 5706 26 during during IN cord-022526-j9kg00qf 5706 27 the the DT cord-022526-j9kg00qf 5706 28 acute acute JJ cord-022526-j9kg00qf 5706 29 stages stage NNS cord-022526-j9kg00qf 5706 30 of of IN cord-022526-j9kg00qf 5706 31 experimentally experimentally RB cord-022526-j9kg00qf 5706 32 induced induce VBN cord-022526-j9kg00qf 5706 33 equine equine JJ cord-022526-j9kg00qf 5706 34 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5706 35 colitis colitis NN cord-022526-j9kg00qf 5706 36 in in IN cord-022526-j9kg00qf 5706 37 ponie ponie NNP cord-022526-j9kg00qf 5706 38 Effect Effect NNP cord-022526-j9kg00qf 5706 39 of of IN cord-022526-j9kg00qf 5706 40 treatment treatment NN cord-022526-j9kg00qf 5706 41 with with IN cord-022526-j9kg00qf 5706 42 erythromycin erythromycin NN cord-022526-j9kg00qf 5706 43 and and CC cord-022526-j9kg00qf 5706 44 rifampin rifampin NN cord-022526-j9kg00qf 5706 45 during during IN cord-022526-j9kg00qf 5706 46 the the DT cord-022526-j9kg00qf 5706 47 acute acute JJ cord-022526-j9kg00qf 5706 48 stages stage NNS cord-022526-j9kg00qf 5706 49 of of IN cord-022526-j9kg00qf 5706 50 experimentally experimentally RB cord-022526-j9kg00qf 5706 51 induced induce VBN cord-022526-j9kg00qf 5706 52 equine equine JJ cord-022526-j9kg00qf 5706 53 ehrlichial ehrlichial JJ cord-022526-j9kg00qf 5706 54 colitis colitis NN cord-022526-j9kg00qf 5706 55 in in IN cord-022526-j9kg00qf 5706 56 ponies pony NNS cord-022526-j9kg00qf 5706 57 Use Use NNP cord-022526-j9kg00qf 5706 58 of of IN cord-022526-j9kg00qf 5706 59 metronidazole metronidazole NNP cord-022526-j9kg00qf 5706 60 in in IN cord-022526-j9kg00qf 5706 61 equine equine JJ cord-022526-j9kg00qf 5706 62 acute acute JJ cord-022526-j9kg00qf 5706 63 idiopathic idiopathic JJ cord-022526-j9kg00qf 5706 64 toxaemic toxaemic JJ cord-022526-j9kg00qf 5706 65 colitis colitis NN cord-022526-j9kg00qf 5706 66 Antimicrobial Antimicrobial NNP cord-022526-j9kg00qf 5706 67 susceptibilities susceptibility NNS cord-022526-j9kg00qf 5706 68 of of IN cord-022526-j9kg00qf 5706 69 equine equine JJ cord-022526-j9kg00qf 5706 70 isolates isolate NNS cord-022526-j9kg00qf 5706 71 of of IN cord-022526-j9kg00qf 5706 72 Clostridium clostridium NN cord-022526-j9kg00qf 5706 73 difficile difficile NN cord-022526-j9kg00qf 5706 74 and and CC cord-022526-j9kg00qf 5706 75 molecular molecular JJ cord-022526-j9kg00qf 5706 76 characterization characterization NN cord-022526-j9kg00qf 5706 77 of of IN cord-022526-j9kg00qf 5706 78 metronidazole metronidazole NN cord-022526-j9kg00qf 5706 79 - - HYPH cord-022526-j9kg00qf 5706 80 resistant resistant JJ cord-022526-j9kg00qf 5706 81 strains strain NNS cord-022526-j9kg00qf 5706 82 Equine equine JJ cord-022526-j9kg00qf 5706 83 neonatal neonatal JJ cord-022526-j9kg00qf 5706 84 clostridiosis clostridiosis NN cord-022526-j9kg00qf 5706 85 : : : cord-022526-j9kg00qf 5706 86 treatment treatment NN cord-022526-j9kg00qf 5706 87 and and CC cord-022526-j9kg00qf 5706 88 prevention prevention NN cord-022526-j9kg00qf 5706 89 Antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5706 90 susceptibility susceptibility NN cord-022526-j9kg00qf 5706 91 of of IN cord-022526-j9kg00qf 5706 92 ileal ileal JJ cord-022526-j9kg00qf 5706 93 symbiont symbiont NN cord-022526-j9kg00qf 5706 94 intracellularis intracellularis NN cord-022526-j9kg00qf 5706 95 isolated isolate VBN cord-022526-j9kg00qf 5706 96 from from IN cord-022526-j9kg00qf 5706 97 pigs pig NNS cord-022526-j9kg00qf 5706 98 with with IN cord-022526-j9kg00qf 5706 99 proliferative proliferative JJ cord-022526-j9kg00qf 5706 100 enteropathy enteropathy NNP cord-022526-j9kg00qf 5706 101 Antithrombotic antithrombotic JJ cord-022526-j9kg00qf 5706 102 actions action NNS cord-022526-j9kg00qf 5706 103 of of IN cord-022526-j9kg00qf 5706 104 aspirin aspirin NN cord-022526-j9kg00qf 5706 105 in in IN cord-022526-j9kg00qf 5706 106 the the DT cord-022526-j9kg00qf 5706 107 horse horse NN cord-022526-j9kg00qf 5706 108 Evaluation Evaluation NNP cord-022526-j9kg00qf 5706 109 of of IN cord-022526-j9kg00qf 5706 110 heparin heparin NN cord-022526-j9kg00qf 5706 111 for for IN cord-022526-j9kg00qf 5706 112 prophylaxis prophylaxis NN cord-022526-j9kg00qf 5706 113 of of IN cord-022526-j9kg00qf 5706 114 equine equine JJ cord-022526-j9kg00qf 5706 115 laminitis laminitis NN cord-022526-j9kg00qf 5706 116 : : : cord-022526-j9kg00qf 5706 117 71 71 CD cord-022526-j9kg00qf 5706 118 cases case NNS cord-022526-j9kg00qf 5706 119 ( ( -LRB- cord-022526-j9kg00qf 5706 120 1980 1980 CD cord-022526-j9kg00qf 5706 121 - - SYM cord-022526-j9kg00qf 5706 122 1986 1986 CD cord-022526-j9kg00qf 5706 123 ) ) -RRB- cord-022526-j9kg00qf 5707 1 Phagocytosis Phagocytosis NNP cord-022526-j9kg00qf 5707 2 of of IN cord-022526-j9kg00qf 5707 3 gelatin gelatin NN cord-022526-j9kg00qf 5707 4 - - HYPH cord-022526-j9kg00qf 5707 5 latex latex NN cord-022526-j9kg00qf 5707 6 particles particle NNS cord-022526-j9kg00qf 5707 7 by by IN cord-022526-j9kg00qf 5707 8 a a DT cord-022526-j9kg00qf 5707 9 murine murine JJ cord-022526-j9kg00qf 5707 10 macrophage macrophage NN cord-022526-j9kg00qf 5707 11 line line NN cord-022526-j9kg00qf 5707 12 is be VBZ cord-022526-j9kg00qf 5707 13 dependent dependent JJ cord-022526-j9kg00qf 5707 14 on on IN cord-022526-j9kg00qf 5707 15 fibronectin fibronectin NN cord-022526-j9kg00qf 5707 16 and and CC cord-022526-j9kg00qf 5707 17 heparin heparin NN cord-022526-j9kg00qf 5707 18 Cold Cold NNP cord-022526-j9kg00qf 5707 19 insoluble insoluble JJ cord-022526-j9kg00qf 5707 20 globulin globulin NN cord-022526-j9kg00qf 5707 21 and and CC cord-022526-j9kg00qf 5707 22 heparin heparin NN cord-022526-j9kg00qf 5707 23 interactions interaction NNS cord-022526-j9kg00qf 5707 24 in in IN cord-022526-j9kg00qf 5707 25 phagocytosis phagocytosis NN cord-022526-j9kg00qf 5707 26 by by IN cord-022526-j9kg00qf 5707 27 macrophage macrophage NN cord-022526-j9kg00qf 5707 28 monolayers monolayer NNS cord-022526-j9kg00qf 5707 29 : : : cord-022526-j9kg00qf 5708 1 mechanism mechanism NN cord-022526-j9kg00qf 5708 2 of of IN cord-022526-j9kg00qf 5708 3 heparin heparin NN cord-022526-j9kg00qf 5708 4 enhancement enhancement NN cord-022526-j9kg00qf 5708 5 Probiotics probiotic NNS cord-022526-j9kg00qf 5708 6 in in IN cord-022526-j9kg00qf 5708 7 man man NN cord-022526-j9kg00qf 5708 8 and and CC cord-022526-j9kg00qf 5708 9 animals animal NNS cord-022526-j9kg00qf 5708 10 Double double JJ cord-022526-j9kg00qf 5708 11 - - HYPH cord-022526-j9kg00qf 5708 12 blind blind JJ cord-022526-j9kg00qf 5708 13 report report NN cord-022526-j9kg00qf 5708 14 on on IN cord-022526-j9kg00qf 5708 15 the the DT cord-022526-j9kg00qf 5708 16 efficacy efficacy NN cord-022526-j9kg00qf 5708 17 of of IN cord-022526-j9kg00qf 5708 18 lactic lactic JJ cord-022526-j9kg00qf 5708 19 acid acid NN cord-022526-j9kg00qf 5708 20 - - HYPH cord-022526-j9kg00qf 5708 21 producing produce VBG cord-022526-j9kg00qf 5708 22 Enterococcus Enterococcus NNP cord-022526-j9kg00qf 5708 23 SF68 SF68 NNP cord-022526-j9kg00qf 5708 24 in in IN cord-022526-j9kg00qf 5708 25 the the DT cord-022526-j9kg00qf 5708 26 prevention prevention NN cord-022526-j9kg00qf 5708 27 of of IN cord-022526-j9kg00qf 5708 28 antibiotic antibiotic NN cord-022526-j9kg00qf 5708 29 - - HYPH cord-022526-j9kg00qf 5708 30 associated associate VBN cord-022526-j9kg00qf 5708 31 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5708 32 and and CC cord-022526-j9kg00qf 5708 33 in in IN cord-022526-j9kg00qf 5708 34 the the DT cord-022526-j9kg00qf 5708 35 treatment treatment NN cord-022526-j9kg00qf 5708 36 of of IN cord-022526-j9kg00qf 5708 37 acute acute JJ cord-022526-j9kg00qf 5708 38 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5708 39 Effect effect NN cord-022526-j9kg00qf 5708 40 of of IN cord-022526-j9kg00qf 5708 41 Lactobacillus lactobacillus NN cord-022526-j9kg00qf 5708 42 GG GG NNP cord-022526-j9kg00qf 5708 43 yoghurt yoghurt NN cord-022526-j9kg00qf 5708 44 in in IN cord-022526-j9kg00qf 5708 45 prevention prevention NN cord-022526-j9kg00qf 5708 46 of of IN cord-022526-j9kg00qf 5708 47 antibiotic antibiotic JJ cord-022526-j9kg00qf 5708 48 associated associate VBN cord-022526-j9kg00qf 5708 49 diarrhoea diarrhoea NN cord-022526-j9kg00qf 5708 50 Comparative comparative JJ cord-022526-j9kg00qf 5708 51 efficacy efficacy NN cord-022526-j9kg00qf 5708 52 of of IN cord-022526-j9kg00qf 5708 53 moxidectin moxidectin NNS cord-022526-j9kg00qf 5708 54 and and CC cord-022526-j9kg00qf 5708 55 ivermectin ivermectin NNP cord-022526-j9kg00qf 5708 56 against against IN cord-022526-j9kg00qf 5708 57 hypobiotic hypobiotic NNP cord-022526-j9kg00qf 5708 58 and and CC cord-022526-j9kg00qf 5708 59 encysted encysted NNP cord-022526-j9kg00qf 5708 60 cyathostomes cyathostomes NNP cord-022526-j9kg00qf 5708 61 and and CC cord-022526-j9kg00qf 5708 62 other other JJ cord-022526-j9kg00qf 5708 63 equine equine JJ cord-022526-j9kg00qf 5708 64 parasites parasite NNS cord-022526-j9kg00qf 5708 65 Efficacy Efficacy NNP cord-022526-j9kg00qf 5708 66 of of IN cord-022526-j9kg00qf 5708 67 oral oral JJ cord-022526-j9kg00qf 5708 68 ivermectin ivermectin NNP cord-022526-j9kg00qf 5708 69 paste paste NN cord-022526-j9kg00qf 5708 70 against against IN cord-022526-j9kg00qf 5708 71 mucosal mucosal JJ cord-022526-j9kg00qf 5708 72 stages stage NNS cord-022526-j9kg00qf 5708 73 of of IN cord-022526-j9kg00qf 5708 74 cyathostomes cyathostomes NNP cord-022526-j9kg00qf 5708 75 Elimination Elimination NNP cord-022526-j9kg00qf 5708 76 of of IN cord-022526-j9kg00qf 5708 77 mucosal mucosal JJ cord-022526-j9kg00qf 5708 78 cyathostome cyathostome NN cord-022526-j9kg00qf 5708 79 larvae larva NNS cord-022526-j9kg00qf 5708 80 by by IN cord-022526-j9kg00qf 5708 81 five five CD cord-022526-j9kg00qf 5708 82 daily daily JJ cord-022526-j9kg00qf 5708 83 treatments treatment NNS cord-022526-j9kg00qf 5708 84 with with IN cord-022526-j9kg00qf 5708 85 fenbendazole fenbendazole NNP cord-022526-j9kg00qf 5708 86 Moxidectin Moxidectin NNP cord-022526-j9kg00qf 5708 87 : : : cord-022526-j9kg00qf 5708 88 spectrum spectrum NN cord-022526-j9kg00qf 5708 89 of of IN cord-022526-j9kg00qf 5708 90 activity activity NN cord-022526-j9kg00qf 5708 91 and and CC cord-022526-j9kg00qf 5708 92 uses use VBZ cord-022526-j9kg00qf 5708 93 in in IN cord-022526-j9kg00qf 5708 94 an an DT cord-022526-j9kg00qf 5708 95 equine equine JJ cord-022526-j9kg00qf 5708 96 anthelmintic anthelmintic JJ cord-022526-j9kg00qf 5708 97 program program NN cord-022526-j9kg00qf 5708 98 REFERENCES reference NNS cord-022526-j9kg00qf 5708 99 1 1 CD cord-022526-j9kg00qf 5708 100 . . . cord-022526-j9kg00qf 5709 1 Laws law NNS cord-022526-j9kg00qf 5709 2 EG EG NNP cord-022526-j9kg00qf 5709 3 , , , cord-022526-j9kg00qf 5709 4 Freeman Freeman NNP cord-022526-j9kg00qf 5709 5 DE DE NNP cord-022526-j9kg00qf 5709 6 : : : cord-022526-j9kg00qf 5709 7 Significance significance NN cord-022526-j9kg00qf 5709 8 of of IN cord-022526-j9kg00qf 5709 9 reperfusion reperfusion NN cord-022526-j9kg00qf 5709 10 injury injury NN cord-022526-j9kg00qf 5709 11 after after IN cord-022526-j9kg00qf 5709 12 venous venous JJ cord-022526-j9kg00qf 5709 13 strangulation strangulation NN cord-022526-j9kg00qf 5709 14 obstruction obstruction NN cord-022526-j9kg00qf 5709 15 of of IN cord-022526-j9kg00qf 5709 16 equine equine JJ cord-022526-j9kg00qf 5709 17 jejunum jejunum NNS cord-022526-j9kg00qf 5710 1 How how WRB cord-022526-j9kg00qf 5710 2 important important JJ cord-022526-j9kg00qf 5710 3 is be VBZ cord-022526-j9kg00qf 5710 4 intestinal intestinal JJ cord-022526-j9kg00qf 5710 5 reperfusion reperfusion NN cord-022526-j9kg00qf 5710 6 injury injury NN cord-022526-j9kg00qf 5710 7 in in IN cord-022526-j9kg00qf 5710 8 horses horse NNS cord-022526-j9kg00qf 5710 9 ? ? . cord-022526-j9kg00qf 5711 1 Clinical clinical JJ cord-022526-j9kg00qf 5711 2 relevance relevance NN cord-022526-j9kg00qf 5711 3 of of IN cord-022526-j9kg00qf 5711 4 intestinal intestinal JJ cord-022526-j9kg00qf 5711 5 reperfusion reperfusion NN cord-022526-j9kg00qf 5711 6 injury injury NN cord-022526-j9kg00qf 5711 7 in in IN cord-022526-j9kg00qf 5711 8 horses horse NNS cord-022526-j9kg00qf 5711 9 Strangulating strangulate VBG cord-022526-j9kg00qf 5711 10 volvulus volvulus NN cord-022526-j9kg00qf 5711 11 of of IN cord-022526-j9kg00qf 5711 12 the the DT cord-022526-j9kg00qf 5711 13 ascending ascend VBG cord-022526-j9kg00qf 5711 14 colon colon NN cord-022526-j9kg00qf 5711 15 in in IN cord-022526-j9kg00qf 5711 16 horses horse NNS cord-022526-j9kg00qf 5712 1 Mucosal Mucosal NNP cord-022526-j9kg00qf 5712 2 alterations alteration NNS cord-022526-j9kg00qf 5712 3 in in IN cord-022526-j9kg00qf 5712 4 experimentally experimentally RB cord-022526-j9kg00qf 5712 5 induced induce VBN cord-022526-j9kg00qf 5712 6 small small JJ cord-022526-j9kg00qf 5712 7 intestinal intestinal JJ cord-022526-j9kg00qf 5712 8 strangulation strangulation NN cord-022526-j9kg00qf 5712 9 obstruction obstruction NN cord-022526-j9kg00qf 5712 10 in in IN cord-022526-j9kg00qf 5712 11 ponies pony NNS cord-022526-j9kg00qf 5712 12 Histologic Histologic NNP cord-022526-j9kg00qf 5712 13 findings finding NNS cord-022526-j9kg00qf 5712 14 in in IN cord-022526-j9kg00qf 5712 15 the the DT cord-022526-j9kg00qf 5712 16 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5712 17 tract tract NN cord-022526-j9kg00qf 5712 18 of of IN cord-022526-j9kg00qf 5712 19 horses horse NNS cord-022526-j9kg00qf 5712 20 with with IN cord-022526-j9kg00qf 5712 21 colic colic NN cord-022526-j9kg00qf 5712 22 Large large JJ cord-022526-j9kg00qf 5712 23 colon colon NN cord-022526-j9kg00qf 5712 24 resection resection NN cord-022526-j9kg00qf 5712 25 Evaluation Evaluation NNP cord-022526-j9kg00qf 5712 26 of of IN cord-022526-j9kg00qf 5712 27 the the DT cord-022526-j9kg00qf 5712 28 microcirculation microcirculation NN cord-022526-j9kg00qf 5712 29 of of IN cord-022526-j9kg00qf 5712 30 the the DT cord-022526-j9kg00qf 5712 31 equine equine JJ cord-022526-j9kg00qf 5712 32 small small JJ cord-022526-j9kg00qf 5712 33 intestine intestine NN cord-022526-j9kg00qf 5712 34 after after IN cord-022526-j9kg00qf 5712 35 intraluminal intraluminal JJ cord-022526-j9kg00qf 5712 36 distention distention NN cord-022526-j9kg00qf 5712 37 and and CC cord-022526-j9kg00qf 5712 38 subsequent subsequent JJ cord-022526-j9kg00qf 5712 39 decompression decompression NN cord-022526-j9kg00qf 5712 40 Mesodiverticular Mesodiverticular NNP cord-022526-j9kg00qf 5712 41 bands band NNS cord-022526-j9kg00qf 5712 42 as as IN cord-022526-j9kg00qf 5712 43 a a DT cord-022526-j9kg00qf 5712 44 cause cause NN cord-022526-j9kg00qf 5712 45 of of IN cord-022526-j9kg00qf 5712 46 small small JJ cord-022526-j9kg00qf 5712 47 intestinal intestinal JJ cord-022526-j9kg00qf 5712 48 strangulation strangulation NN cord-022526-j9kg00qf 5712 49 and and CC cord-022526-j9kg00qf 5712 50 volvulus volvulus NN cord-022526-j9kg00qf 5712 51 in in IN cord-022526-j9kg00qf 5712 52 the the DT cord-022526-j9kg00qf 5712 53 horse horse NN cord-022526-j9kg00qf 5712 54 Induction Induction NNP cord-022526-j9kg00qf 5712 55 of of IN cord-022526-j9kg00qf 5712 56 peritoneal peritoneal JJ cord-022526-j9kg00qf 5712 57 adhesions adhesion NNS cord-022526-j9kg00qf 5712 58 with with IN cord-022526-j9kg00qf 5712 59 small small JJ cord-022526-j9kg00qf 5712 60 intestinal intestinal JJ cord-022526-j9kg00qf 5712 61 ischaemia ischaemia NN cord-022526-j9kg00qf 5712 62 and and CC cord-022526-j9kg00qf 5712 63 distention distention NN cord-022526-j9kg00qf 5712 64 in in IN cord-022526-j9kg00qf 5712 65 the the DT cord-022526-j9kg00qf 5712 66 foal foal NN cord-022526-j9kg00qf 5712 67 Diseases disease NNS cord-022526-j9kg00qf 5712 68 of of IN cord-022526-j9kg00qf 5712 69 the the DT cord-022526-j9kg00qf 5712 70 small small JJ cord-022526-j9kg00qf 5712 71 intestine intestine NN cord-022526-j9kg00qf 5712 72 Small small JJ cord-022526-j9kg00qf 5712 73 intestinal intestinal JJ cord-022526-j9kg00qf 5712 74 herniation herniation NN cord-022526-j9kg00qf 5712 75 through through IN cord-022526-j9kg00qf 5712 76 the the DT cord-022526-j9kg00qf 5712 77 epiploic epiploic JJ cord-022526-j9kg00qf 5712 78 foramen foramen NN cord-022526-j9kg00qf 5712 79 : : : cord-022526-j9kg00qf 5712 80 53 53 CD cord-022526-j9kg00qf 5712 81 cases case NNS cord-022526-j9kg00qf 5712 82 ( ( -LRB- cord-022526-j9kg00qf 5712 83 1987 1987 CD cord-022526-j9kg00qf 5712 84 - - SYM cord-022526-j9kg00qf 5712 85 1993 1993 CD cord-022526-j9kg00qf 5712 86 ) ) -RRB- cord-022526-j9kg00qf 5712 87 Determining determine VBG cord-022526-j9kg00qf 5712 88 the the DT cord-022526-j9kg00qf 5712 89 diagnosis diagnosis NN cord-022526-j9kg00qf 5712 90 and and CC cord-022526-j9kg00qf 5712 91 prognosis prognosis NN cord-022526-j9kg00qf 5712 92 of of IN cord-022526-j9kg00qf 5712 93 the the DT cord-022526-j9kg00qf 5712 94 acute acute JJ cord-022526-j9kg00qf 5712 95 abdomen abdomen JJ cord-022526-j9kg00qf 5712 96 Duodenitis Duodenitis NNP cord-022526-j9kg00qf 5712 97 - - HYPH cord-022526-j9kg00qf 5712 98 proximal proximal JJ cord-022526-j9kg00qf 5712 99 jejunitis jejunitis NNP cord-022526-j9kg00qf 5712 100 Risk risk NN cord-022526-j9kg00qf 5712 101 factors factor NNS cord-022526-j9kg00qf 5712 102 and and CC cord-022526-j9kg00qf 5712 103 clinical clinical JJ cord-022526-j9kg00qf 5712 104 signs sign NNS cord-022526-j9kg00qf 5712 105 associated associate VBN cord-022526-j9kg00qf 5712 106 with with IN cord-022526-j9kg00qf 5712 107 cases case NNS cord-022526-j9kg00qf 5712 108 of of IN cord-022526-j9kg00qf 5712 109 equine equine JJ cord-022526-j9kg00qf 5712 110 colic colic NN cord-022526-j9kg00qf 5712 111 Short short JJ cord-022526-j9kg00qf 5712 112 - - HYPH cord-022526-j9kg00qf 5712 113 term term NN cord-022526-j9kg00qf 5712 114 survival survival NN cord-022526-j9kg00qf 5712 115 and and CC cord-022526-j9kg00qf 5712 116 prevalence prevalence NN cord-022526-j9kg00qf 5712 117 of of IN cord-022526-j9kg00qf 5712 118 postoperative postoperative JJ cord-022526-j9kg00qf 5712 119 ileus ileus NN cord-022526-j9kg00qf 5712 120 after after IN cord-022526-j9kg00qf 5712 121 small small JJ cord-022526-j9kg00qf 5712 122 intestinal intestinal JJ cord-022526-j9kg00qf 5712 123 surgery surgery NN cord-022526-j9kg00qf 5712 124 in in IN cord-022526-j9kg00qf 5712 125 horses horse NNS cord-022526-j9kg00qf 5712 126 Short short JJ cord-022526-j9kg00qf 5712 127 - - HYPH cord-022526-j9kg00qf 5712 128 and and CC cord-022526-j9kg00qf 5712 129 longterm longterm JJ cord-022526-j9kg00qf 5712 130 survival survival NN cord-022526-j9kg00qf 5712 131 and and CC cord-022526-j9kg00qf 5712 132 prevalence prevalence NN cord-022526-j9kg00qf 5712 133 of of IN cord-022526-j9kg00qf 5712 134 postoperative postoperative JJ cord-022526-j9kg00qf 5712 135 ileus ileus NN cord-022526-j9kg00qf 5712 136 after after IN cord-022526-j9kg00qf 5712 137 small small JJ cord-022526-j9kg00qf 5712 138 intestinal intestinal JJ cord-022526-j9kg00qf 5712 139 surgery surgery NN cord-022526-j9kg00qf 5712 140 in in IN cord-022526-j9kg00qf 5712 141 the the DT cord-022526-j9kg00qf 5712 142 horse horse NN cord-022526-j9kg00qf 5712 143 Survival Survival NNP cord-022526-j9kg00qf 5712 144 after after IN cord-022526-j9kg00qf 5712 145 small small JJ cord-022526-j9kg00qf 5712 146 intestine intestine NN cord-022526-j9kg00qf 5712 147 resection resection NN cord-022526-j9kg00qf 5712 148 and and CC cord-022526-j9kg00qf 5712 149 anastomosis anastomosis NN cord-022526-j9kg00qf 5712 150 in in IN cord-022526-j9kg00qf 5712 151 horses horse NNS cord-022526-j9kg00qf 5712 152 Abdominal abdominal JJ cord-022526-j9kg00qf 5712 153 adhesions adhesion NNS cord-022526-j9kg00qf 5712 154 after after IN cord-022526-j9kg00qf 5712 155 small small JJ cord-022526-j9kg00qf 5712 156 intestinal intestinal JJ cord-022526-j9kg00qf 5712 157 surgery surgery NN cord-022526-j9kg00qf 5712 158 in in IN cord-022526-j9kg00qf 5712 159 the the DT cord-022526-j9kg00qf 5712 160 horse horse NN cord-022526-j9kg00qf 5713 1 Mesenteric mesenteric JJ cord-022526-j9kg00qf 5713 2 rents rent NNS cord-022526-j9kg00qf 5713 3 as as IN cord-022526-j9kg00qf 5713 4 a a DT cord-022526-j9kg00qf 5713 5 source source NN cord-022526-j9kg00qf 5713 6 of of IN cord-022526-j9kg00qf 5713 7 small small JJ cord-022526-j9kg00qf 5713 8 intestinal intestinal JJ cord-022526-j9kg00qf 5713 9 strangulation strangulation NN cord-022526-j9kg00qf 5713 10 in in IN cord-022526-j9kg00qf 5713 11 horses horse NNS cord-022526-j9kg00qf 5713 12 : : : cord-022526-j9kg00qf 5713 13 15 15 CD cord-022526-j9kg00qf 5713 14 cases case NNS cord-022526-j9kg00qf 5713 15 ( ( -LRB- cord-022526-j9kg00qf 5713 16 1990 1990 CD cord-022526-j9kg00qf 5713 17 - - SYM cord-022526-j9kg00qf 5713 18 1997 1997 CD cord-022526-j9kg00qf 5713 19 ) ) -RRB- cord-022526-j9kg00qf 5714 1 Small small JJ cord-022526-j9kg00qf 5714 2 intestine intestine NN cord-022526-j9kg00qf 5714 3 incarceration incarceration NN cord-022526-j9kg00qf 5714 4 through through IN cord-022526-j9kg00qf 5714 5 the the DT cord-022526-j9kg00qf 5714 6 epiploic epiploic JJ cord-022526-j9kg00qf 5714 7 foramen foramen NN cord-022526-j9kg00qf 5714 8 of of IN cord-022526-j9kg00qf 5714 9 the the DT cord-022526-j9kg00qf 5714 10 horse horse NN cord-022526-j9kg00qf 5715 1 Right right JJ cord-022526-j9kg00qf 5715 2 hepatic hepatic JJ cord-022526-j9kg00qf 5715 3 lobe lobe NN cord-022526-j9kg00qf 5715 4 atrophy atrophy NN cord-022526-j9kg00qf 5715 5 in in IN cord-022526-j9kg00qf 5715 6 horses horse NNS cord-022526-j9kg00qf 5715 7 : : : cord-022526-j9kg00qf 5715 8 17 17 CD cord-022526-j9kg00qf 5715 9 cases case NNS cord-022526-j9kg00qf 5715 10 Incarceration incarceration NN cord-022526-j9kg00qf 5715 11 of of IN cord-022526-j9kg00qf 5715 12 the the DT cord-022526-j9kg00qf 5715 13 jejunum jejunum NNS cord-022526-j9kg00qf 5715 14 in in IN cord-022526-j9kg00qf 5715 15 the the DT cord-022526-j9kg00qf 5715 16 epiploic epiploic JJ cord-022526-j9kg00qf 5715 17 foramen foramen NN cord-022526-j9kg00qf 5715 18 of of IN cord-022526-j9kg00qf 5715 19 a a DT cord-022526-j9kg00qf 5715 20 four four CD cord-022526-j9kg00qf 5715 21 month month NN cord-022526-j9kg00qf 5715 22 old old JJ cord-022526-j9kg00qf 5715 23 foal foal NN cord-022526-j9kg00qf 5715 24 Use use NN cord-022526-j9kg00qf 5715 25 of of IN cord-022526-j9kg00qf 5715 26 diagnostic diagnostic JJ cord-022526-j9kg00qf 5715 27 ultrasonography ultrasonography NN cord-022526-j9kg00qf 5715 28 in in IN cord-022526-j9kg00qf 5715 29 horses horse NNS cord-022526-j9kg00qf 5715 30 with with IN cord-022526-j9kg00qf 5715 31 signs sign NNS cord-022526-j9kg00qf 5715 32 of of IN cord-022526-j9kg00qf 5715 33 acute acute JJ cord-022526-j9kg00qf 5715 34 abdominal abdominal JJ cord-022526-j9kg00qf 5715 35 pain pain NN cord-022526-j9kg00qf 5715 36 Parietal Parietal NNP cord-022526-j9kg00qf 5715 37 hernia hernia NN cord-022526-j9kg00qf 5715 38 of of IN cord-022526-j9kg00qf 5715 39 the the DT cord-022526-j9kg00qf 5715 40 small small JJ cord-022526-j9kg00qf 5715 41 intestine intestine NN cord-022526-j9kg00qf 5715 42 into into IN cord-022526-j9kg00qf 5715 43 the the DT cord-022526-j9kg00qf 5715 44 epiploic epiploic JJ cord-022526-j9kg00qf 5715 45 foramen foramen NN cord-022526-j9kg00qf 5715 46 of of IN cord-022526-j9kg00qf 5715 47 a a DT cord-022526-j9kg00qf 5715 48 horse horse NN cord-022526-j9kg00qf 5715 49 Transection Transection NNP cord-022526-j9kg00qf 5715 50 of of IN cord-022526-j9kg00qf 5715 51 the the DT cord-022526-j9kg00qf 5715 52 pelvic pelvic JJ cord-022526-j9kg00qf 5715 53 flexure flexure NN cord-022526-j9kg00qf 5715 54 to to TO cord-022526-j9kg00qf 5715 55 reduce reduce VB cord-022526-j9kg00qf 5715 56 incarceration incarceration NN cord-022526-j9kg00qf 5715 57 of of IN cord-022526-j9kg00qf 5715 58 the the DT cord-022526-j9kg00qf 5715 59 large large JJ cord-022526-j9kg00qf 5715 60 colon colon NN cord-022526-j9kg00qf 5715 61 through through IN cord-022526-j9kg00qf 5715 62 the the DT cord-022526-j9kg00qf 5715 63 epiploic epiploic JJ cord-022526-j9kg00qf 5715 64 foramen foramen NN cord-022526-j9kg00qf 5715 65 in in IN cord-022526-j9kg00qf 5715 66 a a DT cord-022526-j9kg00qf 5715 67 horse horse NN cord-022526-j9kg00qf 5715 68 Incarceration incarceration NN cord-022526-j9kg00qf 5715 69 of of IN cord-022526-j9kg00qf 5715 70 the the DT cord-022526-j9kg00qf 5715 71 small small JJ cord-022526-j9kg00qf 5715 72 intestine intestine NN cord-022526-j9kg00qf 5715 73 in in IN cord-022526-j9kg00qf 5715 74 the the DT cord-022526-j9kg00qf 5715 75 epiploic epiploic JJ cord-022526-j9kg00qf 5715 76 foramen foramen NN cord-022526-j9kg00qf 5715 77 : : : cord-022526-j9kg00qf 5716 1 report report NN cord-022526-j9kg00qf 5716 2 of of IN cord-022526-j9kg00qf 5716 3 19 19 CD cord-022526-j9kg00qf 5716 4 cases case NNS cord-022526-j9kg00qf 5716 5 Pedunculated pedunculate VBN cord-022526-j9kg00qf 5716 6 lipomas lipoma NNS cord-022526-j9kg00qf 5716 7 as as IN cord-022526-j9kg00qf 5716 8 a a DT cord-022526-j9kg00qf 5716 9 cause cause NN cord-022526-j9kg00qf 5716 10 of of IN cord-022526-j9kg00qf 5716 11 intestinal intestinal JJ cord-022526-j9kg00qf 5716 12 obstruction obstruction NN cord-022526-j9kg00qf 5716 13 in in IN cord-022526-j9kg00qf 5716 14 horses horse NNS cord-022526-j9kg00qf 5716 15 : : : cord-022526-j9kg00qf 5716 16 17 17 CD cord-022526-j9kg00qf 5716 17 cases case NNS cord-022526-j9kg00qf 5716 18 ( ( -LRB- cord-022526-j9kg00qf 5716 19 1983 1983 CD cord-022526-j9kg00qf 5716 20 - - SYM cord-022526-j9kg00qf 5716 21 1990 1990 CD cord-022526-j9kg00qf 5716 22 ) ) -RRB- cord-022526-j9kg00qf 5717 1 An an DT cord-022526-j9kg00qf 5717 2 analysis analysis NN cord-022526-j9kg00qf 5717 3 of of IN cord-022526-j9kg00qf 5717 4 75 75 CD cord-022526-j9kg00qf 5717 5 cases case NNS cord-022526-j9kg00qf 5717 6 of of IN cord-022526-j9kg00qf 5717 7 intestinal intestinal JJ cord-022526-j9kg00qf 5717 8 obstruction obstruction NN cord-022526-j9kg00qf 5717 9 caused cause VBN cord-022526-j9kg00qf 5717 10 by by IN cord-022526-j9kg00qf 5717 11 pedunculated pedunculate VBN cord-022526-j9kg00qf 5717 12 lipomas lipoma NNS cord-022526-j9kg00qf 5717 13 Strangulation strangulation NN cord-022526-j9kg00qf 5717 14 of of IN cord-022526-j9kg00qf 5717 15 the the DT cord-022526-j9kg00qf 5717 16 rectum rectum NN cord-022526-j9kg00qf 5717 17 of of IN cord-022526-j9kg00qf 5717 18 a a DT cord-022526-j9kg00qf 5717 19 horse horse NN cord-022526-j9kg00qf 5717 20 by by IN cord-022526-j9kg00qf 5717 21 the the DT cord-022526-j9kg00qf 5717 22 pedicle pedicle NN cord-022526-j9kg00qf 5717 23 of of IN cord-022526-j9kg00qf 5717 24 a a DT cord-022526-j9kg00qf 5717 25 mesenteric mesenteric JJ cord-022526-j9kg00qf 5717 26 lipoma lipoma NN cord-022526-j9kg00qf 5717 27 Abdominal abdominal JJ cord-022526-j9kg00qf 5717 28 surgery surgery NN cord-022526-j9kg00qf 5717 29 in in IN cord-022526-j9kg00qf 5717 30 foals foal NNS cord-022526-j9kg00qf 5717 31 Intestinal intestinal JJ cord-022526-j9kg00qf 5717 32 surgery surgery NN cord-022526-j9kg00qf 5717 33 in in IN cord-022526-j9kg00qf 5717 34 the the DT cord-022526-j9kg00qf 5717 35 foal foal NN cord-022526-j9kg00qf 5717 36 Effects effect NNS cord-022526-j9kg00qf 5717 37 of of IN cord-022526-j9kg00qf 5717 38 extensive extensive JJ cord-022526-j9kg00qf 5717 39 resection resection NN cord-022526-j9kg00qf 5717 40 of of IN cord-022526-j9kg00qf 5717 41 the the DT cord-022526-j9kg00qf 5717 42 small small JJ cord-022526-j9kg00qf 5717 43 intestine intestine NN cord-022526-j9kg00qf 5717 44 in in IN cord-022526-j9kg00qf 5717 45 the the DT cord-022526-j9kg00qf 5717 46 pony pony NN cord-022526-j9kg00qf 5717 47 Incarceration incarceration NN cord-022526-j9kg00qf 5717 48 of of IN cord-022526-j9kg00qf 5717 49 small small JJ cord-022526-j9kg00qf 5717 50 intestine intestine NN cord-022526-j9kg00qf 5717 51 through through IN cord-022526-j9kg00qf 5717 52 rents rent NNS cord-022526-j9kg00qf 5717 53 in in IN cord-022526-j9kg00qf 5717 54 the the DT cord-022526-j9kg00qf 5717 55 gastrosplenic gastrosplenic NNP cord-022526-j9kg00qf 5717 56 ligament ligament NN cord-022526-j9kg00qf 5717 57 in in IN cord-022526-j9kg00qf 5717 58 the the DT cord-022526-j9kg00qf 5717 59 horse horse NN cord-022526-j9kg00qf 5717 60 Jejunal Jejunal NNP cord-022526-j9kg00qf 5717 61 displacement displacement NN cord-022526-j9kg00qf 5717 62 through through IN cord-022526-j9kg00qf 5717 63 the the DT cord-022526-j9kg00qf 5717 64 mesometrium mesometrium NN cord-022526-j9kg00qf 5717 65 in in IN cord-022526-j9kg00qf 5717 66 a a DT cord-022526-j9kg00qf 5717 67 pregnant pregnant JJ cord-022526-j9kg00qf 5717 68 mare mare NN cord-022526-j9kg00qf 5717 69 Strangulating strangulating JJ cord-022526-j9kg00qf 5717 70 obstruction obstruction NN cord-022526-j9kg00qf 5717 71 caused cause VBN cord-022526-j9kg00qf 5717 72 by by IN cord-022526-j9kg00qf 5717 73 intestinal intestinal JJ cord-022526-j9kg00qf 5717 74 herniation herniation NN cord-022526-j9kg00qf 5717 75 through through IN cord-022526-j9kg00qf 5717 76 the the DT cord-022526-j9kg00qf 5717 77 proximal proximal JJ cord-022526-j9kg00qf 5717 78 aspect aspect NN cord-022526-j9kg00qf 5717 79 of of IN cord-022526-j9kg00qf 5717 80 the the DT cord-022526-j9kg00qf 5717 81 cecocolic cecocolic NN cord-022526-j9kg00qf 5717 82 fold fold VBP cord-022526-j9kg00qf 5717 83 in in IN cord-022526-j9kg00qf 5717 84 9 9 CD cord-022526-j9kg00qf 5717 85 horses horse NNS cord-022526-j9kg00qf 5718 1 Congenital congenital JJ cord-022526-j9kg00qf 5718 2 inguinal inguinal JJ cord-022526-j9kg00qf 5718 3 hernias hernia NNS cord-022526-j9kg00qf 5718 4 associated associate VBN cord-022526-j9kg00qf 5718 5 with with IN cord-022526-j9kg00qf 5718 6 a a DT cord-022526-j9kg00qf 5718 7 rent rent NN cord-022526-j9kg00qf 5718 8 in in IN cord-022526-j9kg00qf 5718 9 the the DT cord-022526-j9kg00qf 5718 10 common common JJ cord-022526-j9kg00qf 5718 11 vaginal vaginal JJ cord-022526-j9kg00qf 5718 12 tunic tunic NN cord-022526-j9kg00qf 5718 13 in in IN cord-022526-j9kg00qf 5718 14 five five CD cord-022526-j9kg00qf 5718 15 foals foal NNS cord-022526-j9kg00qf 5718 16 Ruptured rupture VBD cord-022526-j9kg00qf 5718 17 inguinal inguinal JJ cord-022526-j9kg00qf 5718 18 hernia hernia NN cord-022526-j9kg00qf 5718 19 in in IN cord-022526-j9kg00qf 5718 20 new new RB cord-022526-j9kg00qf 5718 21 - - HYPH cord-022526-j9kg00qf 5718 22 born bear VBN cord-022526-j9kg00qf 5718 23 colt colt NN cord-022526-j9kg00qf 5718 24 foals foal NNS cord-022526-j9kg00qf 5718 25 : : : cord-022526-j9kg00qf 5718 26 a a DT cord-022526-j9kg00qf 5718 27 review review NN cord-022526-j9kg00qf 5718 28 of of IN cord-022526-j9kg00qf 5718 29 14 14 CD cord-022526-j9kg00qf 5718 30 cases case NNS cord-022526-j9kg00qf 5718 31 Acquired acquire VBN cord-022526-j9kg00qf 5718 32 inguinal inguinal JJ cord-022526-j9kg00qf 5718 33 hernia hernia NN cord-022526-j9kg00qf 5718 34 in in IN cord-022526-j9kg00qf 5718 35 the the DT cord-022526-j9kg00qf 5718 36 horse horse NN cord-022526-j9kg00qf 5718 37 : : : cord-022526-j9kg00qf 5718 38 a a DT cord-022526-j9kg00qf 5718 39 review review NN cord-022526-j9kg00qf 5718 40 of of IN cord-022526-j9kg00qf 5718 41 27 27 CD cord-022526-j9kg00qf 5718 42 cases case NNS cord-022526-j9kg00qf 5718 43 Surgical surgical JJ cord-022526-j9kg00qf 5718 44 treatment treatment NN cord-022526-j9kg00qf 5718 45 of of IN cord-022526-j9kg00qf 5718 46 acquired acquire VBN cord-022526-j9kg00qf 5718 47 inguinal inguinal JJ cord-022526-j9kg00qf 5718 48 hernia hernia NN cord-022526-j9kg00qf 5718 49 in in IN cord-022526-j9kg00qf 5718 50 the the DT cord-022526-j9kg00qf 5718 51 horse horse NN cord-022526-j9kg00qf 5718 52 : : : cord-022526-j9kg00qf 5718 53 a a DT cord-022526-j9kg00qf 5718 54 review review NN cord-022526-j9kg00qf 5718 55 of of IN cord-022526-j9kg00qf 5718 56 51 51 CD cord-022526-j9kg00qf 5718 57 cases case NNS cord-022526-j9kg00qf 5718 58 Different different JJ cord-022526-j9kg00qf 5718 59 types type NNS cord-022526-j9kg00qf 5718 60 of of IN cord-022526-j9kg00qf 5718 61 inguinal inguinal JJ cord-022526-j9kg00qf 5718 62 herniation herniation NN cord-022526-j9kg00qf 5718 63 in in IN cord-022526-j9kg00qf 5718 64 two two CD cord-022526-j9kg00qf 5718 65 stallions stallion NNS cord-022526-j9kg00qf 5718 66 and and CC cord-022526-j9kg00qf 5718 67 a a DT cord-022526-j9kg00qf 5718 68 gelding geld VBG cord-022526-j9kg00qf 5718 69 Surgery surgery NN cord-022526-j9kg00qf 5718 70 of of IN cord-022526-j9kg00qf 5718 71 the the DT cord-022526-j9kg00qf 5718 72 small small JJ cord-022526-j9kg00qf 5718 73 intestine intestine NN cord-022526-j9kg00qf 5718 74 Complications complication NNS cord-022526-j9kg00qf 5718 75 of of IN cord-022526-j9kg00qf 5718 76 umbilical umbilical JJ cord-022526-j9kg00qf 5718 77 hernias hernia NNS cord-022526-j9kg00qf 5718 78 in in IN cord-022526-j9kg00qf 5718 79 horses horse NNS cord-022526-j9kg00qf 5718 80 : : : cord-022526-j9kg00qf 5718 81 13 13 CD cord-022526-j9kg00qf 5718 82 cases case NNS cord-022526-j9kg00qf 5718 83 Strangulated strangulated JJ cord-022526-j9kg00qf 5718 84 umbilical umbilical JJ cord-022526-j9kg00qf 5718 85 hernias hernia NNS cord-022526-j9kg00qf 5718 86 in in IN cord-022526-j9kg00qf 5718 87 horses horse NNS cord-022526-j9kg00qf 5718 88 : : : cord-022526-j9kg00qf 5718 89 13 13 CD cord-022526-j9kg00qf 5718 90 cases case NNS cord-022526-j9kg00qf 5718 91 ( ( -LRB- cord-022526-j9kg00qf 5718 92 1974 1974 CD cord-022526-j9kg00qf 5718 93 - - SYM cord-022526-j9kg00qf 5718 94 1985 1985 CD cord-022526-j9kg00qf 5718 95 ) ) -RRB- cord-022526-j9kg00qf 5719 1 Surgical surgical JJ cord-022526-j9kg00qf 5719 2 management management NN cord-022526-j9kg00qf 5719 3 of of IN cord-022526-j9kg00qf 5719 4 intussusception intussusception NN cord-022526-j9kg00qf 5719 5 in in IN cord-022526-j9kg00qf 5719 6 the the DT cord-022526-j9kg00qf 5719 7 horse horse NN cord-022526-j9kg00qf 5719 8 Ileocecal Ileocecal NNP cord-022526-j9kg00qf 5719 9 intussusception intussusception NN cord-022526-j9kg00qf 5719 10 in in IN cord-022526-j9kg00qf 5719 11 horses horse NNS cord-022526-j9kg00qf 5719 12 : : : cord-022526-j9kg00qf 5720 1 26 26 CD cord-022526-j9kg00qf 5720 2 cases case NNS cord-022526-j9kg00qf 5720 3 Ultrasonographic ultrasonographic JJ cord-022526-j9kg00qf 5720 4 diagnosis diagnosis NN cord-022526-j9kg00qf 5720 5 of of IN cord-022526-j9kg00qf 5720 6 small small JJ cord-022526-j9kg00qf 5720 7 - - HYPH cord-022526-j9kg00qf 5720 8 intestinal intestinal JJ cord-022526-j9kg00qf 5720 9 intussusception intussusception NN cord-022526-j9kg00qf 5720 10 in in IN cord-022526-j9kg00qf 5720 11 three three CD cord-022526-j9kg00qf 5720 12 foals foal NNS cord-022526-j9kg00qf 5720 13 Jejunal Jejunal NNP cord-022526-j9kg00qf 5720 14 intussusception intussusception NN cord-022526-j9kg00qf 5720 15 in in IN cord-022526-j9kg00qf 5720 16 adult adult NN cord-022526-j9kg00qf 5720 17 horses horse NNS cord-022526-j9kg00qf 5720 18 : : : cord-022526-j9kg00qf 5720 19 11 11 CD cord-022526-j9kg00qf 5720 20 cases case NNS cord-022526-j9kg00qf 5721 1 Ileocecal ileocecal JJ cord-022526-j9kg00qf 5721 2 intussusception intussusception NN cord-022526-j9kg00qf 5721 3 corrected correct VBN cord-022526-j9kg00qf 5721 4 by by IN cord-022526-j9kg00qf 5721 5 resection resection NN cord-022526-j9kg00qf 5721 6 within within IN cord-022526-j9kg00qf 5721 7 the the DT cord-022526-j9kg00qf 5721 8 cecum cecum NN cord-022526-j9kg00qf 5721 9 in in IN cord-022526-j9kg00qf 5721 10 two two CD cord-022526-j9kg00qf 5721 11 horses horse NNS cord-022526-j9kg00qf 5721 12 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5721 13 hernias hernia NNS cord-022526-j9kg00qf 5721 14 in in IN cord-022526-j9kg00qf 5721 15 horses horse NNS cord-022526-j9kg00qf 5721 16 and and CC cord-022526-j9kg00qf 5721 17 cattle cattle NNS cord-022526-j9kg00qf 5721 18 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5721 19 hernias hernia NNS cord-022526-j9kg00qf 5721 20 in in IN cord-022526-j9kg00qf 5721 21 the the DT cord-022526-j9kg00qf 5721 22 horse horse NN cord-022526-j9kg00qf 5721 23 : : : cord-022526-j9kg00qf 5722 1 a a DT cord-022526-j9kg00qf 5722 2 review review NN cord-022526-j9kg00qf 5722 3 of of IN cord-022526-j9kg00qf 5722 4 the the DT cord-022526-j9kg00qf 5722 5 literature literature NN cord-022526-j9kg00qf 5722 6 and and CC cord-022526-j9kg00qf 5722 7 an an DT cord-022526-j9kg00qf 5722 8 analysis analysis NN cord-022526-j9kg00qf 5722 9 of of IN cord-022526-j9kg00qf 5722 10 six six CD cord-022526-j9kg00qf 5722 11 additional additional JJ cord-022526-j9kg00qf 5722 12 cases case NNS cord-022526-j9kg00qf 5722 13 Peritoneopericardial Peritoneopericardial NNP cord-022526-j9kg00qf 5722 14 hernia hernia NN cord-022526-j9kg00qf 5722 15 in in IN cord-022526-j9kg00qf 5722 16 a a DT cord-022526-j9kg00qf 5722 17 horse horse NN cord-022526-j9kg00qf 5722 18 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5722 19 herniation herniation NN cord-022526-j9kg00qf 5722 20 as as IN cord-022526-j9kg00qf 5722 21 a a DT cord-022526-j9kg00qf 5722 22 cause cause NN cord-022526-j9kg00qf 5722 23 of of IN cord-022526-j9kg00qf 5722 24 lethargy lethargy NN cord-022526-j9kg00qf 5722 25 and and CC cord-022526-j9kg00qf 5722 26 exercise exercise VB cord-022526-j9kg00qf 5722 27 intolerance intolerance NN cord-022526-j9kg00qf 5722 28 in in IN cord-022526-j9kg00qf 5722 29 a a DT cord-022526-j9kg00qf 5722 30 mare mare JJ cord-022526-j9kg00qf 5722 31 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5722 32 hernia hernia NN cord-022526-j9kg00qf 5722 33 repair repair NN cord-022526-j9kg00qf 5722 34 in in IN cord-022526-j9kg00qf 5722 35 three three CD cord-022526-j9kg00qf 5722 36 young young JJ cord-022526-j9kg00qf 5722 37 horses horse NNS cord-022526-j9kg00qf 5722 38 Surgical surgical JJ cord-022526-j9kg00qf 5722 39 repair repair NN cord-022526-j9kg00qf 5722 40 of of IN cord-022526-j9kg00qf 5722 41 a a DT cord-022526-j9kg00qf 5722 42 diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5722 43 hernia hernia NN cord-022526-j9kg00qf 5722 44 in in IN cord-022526-j9kg00qf 5722 45 a a DT cord-022526-j9kg00qf 5722 46 racehorse racehorse NN cord-022526-j9kg00qf 5722 47 Diaphragmatic diaphragmatic JJ cord-022526-j9kg00qf 5722 48 hernias hernia NNS cord-022526-j9kg00qf 5722 49 in in IN cord-022526-j9kg00qf 5722 50 the the DT cord-022526-j9kg00qf 5722 51 horse horse NN cord-022526-j9kg00qf 5722 52 : : : cord-022526-j9kg00qf 5722 53 a a DT cord-022526-j9kg00qf 5722 54 review review NN cord-022526-j9kg00qf 5722 55 of of IN cord-022526-j9kg00qf 5722 56 the the DT cord-022526-j9kg00qf 5722 57 literature literature NN cord-022526-j9kg00qf 5722 58 and and CC cord-022526-j9kg00qf 5722 59 an an DT cord-022526-j9kg00qf 5722 60 analysis analysis NN cord-022526-j9kg00qf 5722 61 of of IN cord-022526-j9kg00qf 5722 62 six six CD cord-022526-j9kg00qf 5722 63 additional additional JJ cord-022526-j9kg00qf 5722 64 cases case NNS cord-022526-j9kg00qf 5722 65 Morphologic morphologic JJ cord-022526-j9kg00qf 5722 66 alterations alteration NNS cord-022526-j9kg00qf 5722 67 observed observe VBN cord-022526-j9kg00qf 5722 68 during during IN cord-022526-j9kg00qf 5722 69 experimental experimental JJ cord-022526-j9kg00qf 5722 70 ischemia ischemia NN cord-022526-j9kg00qf 5722 71 of of IN cord-022526-j9kg00qf 5722 72 the the DT cord-022526-j9kg00qf 5722 73 equine equine JJ cord-022526-j9kg00qf 5722 74 large large JJ cord-022526-j9kg00qf 5722 75 colon colon NN cord-022526-j9kg00qf 5722 76 Equine equine JJ cord-022526-j9kg00qf 5722 77 large large JJ cord-022526-j9kg00qf 5722 78 intestinal intestinal JJ cord-022526-j9kg00qf 5722 79 volvulus volvulus NN cord-022526-j9kg00qf 5722 80 : : : cord-022526-j9kg00qf 5722 81 a a DT cord-022526-j9kg00qf 5722 82 review review NN cord-022526-j9kg00qf 5722 83 of of IN cord-022526-j9kg00qf 5722 84 124 124 CD cord-022526-j9kg00qf 5722 85 cases case NNS cord-022526-j9kg00qf 5722 86 Diseases disease NNS cord-022526-j9kg00qf 5722 87 and and CC cord-022526-j9kg00qf 5722 88 surgery surgery NN cord-022526-j9kg00qf 5722 89 of of IN cord-022526-j9kg00qf 5722 90 the the DT cord-022526-j9kg00qf 5722 91 large large JJ cord-022526-j9kg00qf 5722 92 colon colon NN cord-022526-j9kg00qf 5722 93 Large large JJ cord-022526-j9kg00qf 5722 94 colon colon NN cord-022526-j9kg00qf 5722 95 volvulus volvulus NN cord-022526-j9kg00qf 5722 96 : : : cord-022526-j9kg00qf 5722 97 surgical surgical JJ cord-022526-j9kg00qf 5722 98 treatment treatment NN cord-022526-j9kg00qf 5722 99 of of IN cord-022526-j9kg00qf 5722 100 204 204 CD cord-022526-j9kg00qf 5722 101 horses horse NNS cord-022526-j9kg00qf 5722 102 Colopexy Colopexy NNP cord-022526-j9kg00qf 5722 103 in in IN cord-022526-j9kg00qf 5722 104 broodmares broodmare NNS cord-022526-j9kg00qf 5722 105 : : : cord-022526-j9kg00qf 5723 1 44 44 CD cord-022526-j9kg00qf 5723 2 cases case NNS cord-022526-j9kg00qf 5724 1 Cecocolic cecocolic JJ cord-022526-j9kg00qf 5724 2 intussusception intussusception NN cord-022526-j9kg00qf 5724 3 in in IN cord-022526-j9kg00qf 5724 4 horses horse NNS cord-022526-j9kg00qf 5724 5 : : : cord-022526-j9kg00qf 5724 6 11 11 CD cord-022526-j9kg00qf 5724 7 cases case NNS cord-022526-j9kg00qf 5724 8 ( ( -LRB- cord-022526-j9kg00qf 5724 9 1979 1979 CD cord-022526-j9kg00qf 5724 10 - - SYM cord-022526-j9kg00qf 5724 11 1989 1989 CD cord-022526-j9kg00qf 5724 12 ) ) -RRB- cord-022526-j9kg00qf 5725 1 Cecocolic cecocolic JJ cord-022526-j9kg00qf 5725 2 and and CC cord-022526-j9kg00qf 5725 3 cecocecal cecocecal JJ cord-022526-j9kg00qf 5725 4 intussusception intussusception NN cord-022526-j9kg00qf 5725 5 in in IN cord-022526-j9kg00qf 5725 6 horses horse NNS cord-022526-j9kg00qf 5725 7 : : : cord-022526-j9kg00qf 5725 8 30 30 CD cord-022526-j9kg00qf 5725 9 cases case NNS cord-022526-j9kg00qf 5725 10 ( ( -LRB- cord-022526-j9kg00qf 5725 11 1976 1976 CD cord-022526-j9kg00qf 5725 12 - - SYM cord-022526-j9kg00qf 5725 13 1996 1996 CD cord-022526-j9kg00qf 5725 14 ) ) -RRB- cord-022526-j9kg00qf 5726 1 Cecal Cecal NNP cord-022526-j9kg00qf 5726 2 amputation amputation NN cord-022526-j9kg00qf 5726 3 via via IN cord-022526-j9kg00qf 5726 4 a a DT cord-022526-j9kg00qf 5726 5 right right JJ cord-022526-j9kg00qf 5726 6 ventral ventral JJ cord-022526-j9kg00qf 5726 7 colon colon NN cord-022526-j9kg00qf 5726 8 enterotomy enterotomy NNP cord-022526-j9kg00qf 5726 9 for for IN cord-022526-j9kg00qf 5726 10 correction correction NN cord-022526-j9kg00qf 5726 11 of of IN cord-022526-j9kg00qf 5726 12 nonreducible nonreducible JJ cord-022526-j9kg00qf 5726 13 cecocolic cecocolic JJ cord-022526-j9kg00qf 5726 14 intussusception intussusception NN cord-022526-j9kg00qf 5726 15 in in IN cord-022526-j9kg00qf 5726 16 8 8 CD cord-022526-j9kg00qf 5726 17 horses horse NNS cord-022526-j9kg00qf 5726 18 Resection Resection NNP cord-022526-j9kg00qf 5726 19 of of IN cord-022526-j9kg00qf 5726 20 intussuscepted intussuscepted JJ cord-022526-j9kg00qf 5726 21 large large JJ cord-022526-j9kg00qf 5726 22 colon colon NN cord-022526-j9kg00qf 5726 23 in in IN cord-022526-j9kg00qf 5726 24 a a DT cord-022526-j9kg00qf 5726 25 horse horse NN cord-022526-j9kg00qf 5726 26 Intussusception intussusception NN cord-022526-j9kg00qf 5726 27 of of IN cord-022526-j9kg00qf 5726 28 the the DT cord-022526-j9kg00qf 5726 29 large large JJ cord-022526-j9kg00qf 5726 30 colon colon NN cord-022526-j9kg00qf 5726 31 in in IN cord-022526-j9kg00qf 5726 32 a a DT cord-022526-j9kg00qf 5726 33 horse horse NN cord-022526-j9kg00qf 5726 34 Intussusception intussusception NN cord-022526-j9kg00qf 5726 35 of of IN cord-022526-j9kg00qf 5726 36 the the DT cord-022526-j9kg00qf 5726 37 left left JJ cord-022526-j9kg00qf 5726 38 dorsal dorsal JJ cord-022526-j9kg00qf 5726 39 colon colon NN cord-022526-j9kg00qf 5726 40 in in IN cord-022526-j9kg00qf 5726 41 a a DT cord-022526-j9kg00qf 5726 42 horse horse NN cord-022526-j9kg00qf 5726 43 Intussusception intussusception NN cord-022526-j9kg00qf 5726 44 of of IN cord-022526-j9kg00qf 5726 45 the the DT cord-022526-j9kg00qf 5726 46 colon colon NN cord-022526-j9kg00qf 5726 47 in in IN cord-022526-j9kg00qf 5726 48 a a DT cord-022526-j9kg00qf 5726 49 filly filly JJ cord-022526-j9kg00qf 5726 50 Rectal rectal JJ cord-022526-j9kg00qf 5726 51 prolapse prolapse NN cord-022526-j9kg00qf 5726 52 in in IN cord-022526-j9kg00qf 5726 53 the the DT cord-022526-j9kg00qf 5726 54 horse horse NN cord-022526-j9kg00qf 5726 55 Rectal rectal JJ cord-022526-j9kg00qf 5726 56 prolapse prolapse NN cord-022526-j9kg00qf 5726 57 and and CC cord-022526-j9kg00qf 5726 58 cystic cystic JJ cord-022526-j9kg00qf 5726 59 calculus calculus NN cord-022526-j9kg00qf 5726 60 in in IN cord-022526-j9kg00qf 5726 61 a a DT cord-022526-j9kg00qf 5726 62 burro burro NN cord-022526-j9kg00qf 5726 63 Rectal rectal JJ cord-022526-j9kg00qf 5726 64 prolapse prolapse NN cord-022526-j9kg00qf 5726 65 in in IN cord-022526-j9kg00qf 5726 66 a a DT cord-022526-j9kg00qf 5726 67 foaling foaling NN cord-022526-j9kg00qf 5726 68 mare mare NN cord-022526-j9kg00qf 5726 69 Management Management NNP cord-022526-j9kg00qf 5726 70 of of IN cord-022526-j9kg00qf 5726 71 rectal rectal JJ cord-022526-j9kg00qf 5726 72 injuries injury NNS cord-022526-j9kg00qf 5726 73 Rectum rectum NN cord-022526-j9kg00qf 5726 74 and and CC cord-022526-j9kg00qf 5726 75 anus anus NN cord-022526-j9kg00qf 5726 76 Disruption disruption NN cord-022526-j9kg00qf 5726 77 to to IN cord-022526-j9kg00qf 5726 78 the the DT cord-022526-j9kg00qf 5726 79 blood blood NN cord-022526-j9kg00qf 5726 80 supply supply NN cord-022526-j9kg00qf 5726 81 to to IN cord-022526-j9kg00qf 5726 82 the the DT cord-022526-j9kg00qf 5726 83 small small JJ cord-022526-j9kg00qf 5726 84 colon colon NN cord-022526-j9kg00qf 5726 85 following follow VBG cord-022526-j9kg00qf 5726 86 rectal rectal JJ cord-022526-j9kg00qf 5726 87 prolapse prolapse NN cord-022526-j9kg00qf 5726 88 and and CC cord-022526-j9kg00qf 5726 89 small small JJ cord-022526-j9kg00qf 5726 90 colon colon NN cord-022526-j9kg00qf 5726 91 intussusception intussusception NN cord-022526-j9kg00qf 5726 92 in in IN cord-022526-j9kg00qf 5726 93 a a DT cord-022526-j9kg00qf 5726 94 mare mare NN cord-022526-j9kg00qf 5726 95 Laparoscopic Laparoscopic NNP cord-022526-j9kg00qf 5726 96 diagnosis diagnosis NN cord-022526-j9kg00qf 5726 97 of of IN cord-022526-j9kg00qf 5726 98 ischemic ischemic JJ cord-022526-j9kg00qf 5726 99 necrosis necrosis NN cord-022526-j9kg00qf 5726 100 of of IN cord-022526-j9kg00qf 5726 101 the the DT cord-022526-j9kg00qf 5726 102 descending descend VBG cord-022526-j9kg00qf 5726 103 colon colon NN cord-022526-j9kg00qf 5726 104 after after IN cord-022526-j9kg00qf 5726 105 rectal rectal JJ cord-022526-j9kg00qf 5726 106 prolapse prolapse NN cord-022526-j9kg00qf 5726 107 and and CC cord-022526-j9kg00qf 5726 108 rupture rupture NN cord-022526-j9kg00qf 5726 109 of of IN cord-022526-j9kg00qf 5726 110 the the DT cord-022526-j9kg00qf 5726 111 mesocolon mesocolon NN cord-022526-j9kg00qf 5726 112 in in IN cord-022526-j9kg00qf 5726 113 two two CD cord-022526-j9kg00qf 5726 114 postpartum postpartum NN cord-022526-j9kg00qf 5726 115 mares mare NNS cord-022526-j9kg00qf 5726 116 Intestinal intestinal JJ cord-022526-j9kg00qf 5726 117 infarction infarction NN cord-022526-j9kg00qf 5726 118 associated associate VBN cord-022526-j9kg00qf 5726 119 with with IN cord-022526-j9kg00qf 5726 120 mesenteric mesenteric JJ cord-022526-j9kg00qf 5726 121 vascular vascular JJ cord-022526-j9kg00qf 5726 122 thrombotic thrombotic JJ cord-022526-j9kg00qf 5726 123 disease disease NN cord-022526-j9kg00qf 5726 124 in in IN cord-022526-j9kg00qf 5726 125 the the DT cord-022526-j9kg00qf 5726 126 horse horse NN cord-022526-j9kg00qf 5726 127 Diseases disease NNS cord-022526-j9kg00qf 5726 128 of of IN cord-022526-j9kg00qf 5726 129 the the DT cord-022526-j9kg00qf 5726 130 large large JJ cord-022526-j9kg00qf 5726 131 colon colon NN cord-022526-j9kg00qf 5726 132 Diagnostic diagnostic JJ cord-022526-j9kg00qf 5726 133 and and CC cord-022526-j9kg00qf 5726 134 prognostic prognostic JJ cord-022526-j9kg00qf 5726 135 procedures procedure NNS cord-022526-j9kg00qf 5726 136 for for IN cord-022526-j9kg00qf 5726 137 equine equine JJ cord-022526-j9kg00qf 5726 138 colic colic NN cord-022526-j9kg00qf 5726 139 surgery surgery NN cord-022526-j9kg00qf 5726 140 Examination examination NN cord-022526-j9kg00qf 5726 141 of of IN cord-022526-j9kg00qf 5726 142 the the DT cord-022526-j9kg00qf 5726 143 horse horse NN cord-022526-j9kg00qf 5726 144 with with IN cord-022526-j9kg00qf 5726 145 colic colic NN cord-022526-j9kg00qf 5726 146 Detection detection NN cord-022526-j9kg00qf 5726 147 of of IN cord-022526-j9kg00qf 5726 148 endotoxin endotoxin NN cord-022526-j9kg00qf 5726 149 in in IN cord-022526-j9kg00qf 5726 150 cases case NNS cord-022526-j9kg00qf 5726 151 of of IN cord-022526-j9kg00qf 5726 152 equine equine JJ cord-022526-j9kg00qf 5726 153 colic colic NN cord-022526-j9kg00qf 5726 154 Determining determine VBG cord-022526-j9kg00qf 5726 155 the the DT cord-022526-j9kg00qf 5726 156 diagnosis diagnosis NN cord-022526-j9kg00qf 5726 157 and and CC cord-022526-j9kg00qf 5726 158 prognosis prognosis NN cord-022526-j9kg00qf 5726 159 of of IN cord-022526-j9kg00qf 5726 160 the the DT cord-022526-j9kg00qf 5726 161 acute acute JJ cord-022526-j9kg00qf 5726 162 abdomen abdomen JJ cord-022526-j9kg00qf 5726 163 Risk risk NN cord-022526-j9kg00qf 5726 164 factors factor NNS cord-022526-j9kg00qf 5726 165 and and CC cord-022526-j9kg00qf 5726 166 clinical clinical JJ cord-022526-j9kg00qf 5726 167 signs sign NNS cord-022526-j9kg00qf 5726 168 associated associate VBN cord-022526-j9kg00qf 5726 169 with with IN cord-022526-j9kg00qf 5726 170 cases case NNS cord-022526-j9kg00qf 5726 171 of of IN cord-022526-j9kg00qf 5726 172 equine equine JJ cord-022526-j9kg00qf 5726 173 colic colic NN cord-022526-j9kg00qf 5726 174 Accuracy accuracy NN cord-022526-j9kg00qf 5726 175 of of IN cord-022526-j9kg00qf 5726 176 clinicians clinician NNS cord-022526-j9kg00qf 5726 177 in in IN cord-022526-j9kg00qf 5726 178 predicting predict VBG cord-022526-j9kg00qf 5726 179 site site NN cord-022526-j9kg00qf 5726 180 and and CC cord-022526-j9kg00qf 5726 181 type type NN cord-022526-j9kg00qf 5726 182 of of IN cord-022526-j9kg00qf 5726 183 lesion lesion NN cord-022526-j9kg00qf 5726 184 as as RB cord-022526-j9kg00qf 5726 185 well well RB cord-022526-j9kg00qf 5726 186 as as IN cord-022526-j9kg00qf 5726 187 outcome outcome NN cord-022526-j9kg00qf 5726 188 in in IN cord-022526-j9kg00qf 5726 189 horses horse NNS cord-022526-j9kg00qf 5726 190 with with IN cord-022526-j9kg00qf 5726 191 colic colic NN cord-022526-j9kg00qf 5727 1 Struvite struvite JJ cord-022526-j9kg00qf 5727 2 urethral urethral JJ cord-022526-j9kg00qf 5727 3 calculus calculus NN cord-022526-j9kg00qf 5727 4 in in IN cord-022526-j9kg00qf 5727 5 a a DT cord-022526-j9kg00qf 5727 6 three three CD cord-022526-j9kg00qf 5727 7 - - HYPH cord-022526-j9kg00qf 5727 8 month month NN cord-022526-j9kg00qf 5727 9 - - HYPH cord-022526-j9kg00qf 5727 10 old old JJ cord-022526-j9kg00qf 5727 11 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5727 12 colt colt NN cord-022526-j9kg00qf 5727 13 Urolithiasis Urolithiasis NNP cord-022526-j9kg00qf 5727 14 in in IN cord-022526-j9kg00qf 5727 15 68 68 CD cord-022526-j9kg00qf 5727 16 horses horse NNS cord-022526-j9kg00qf 5727 17 Cholelithiasis Cholelithiasis NNP cord-022526-j9kg00qf 5727 18 in in IN cord-022526-j9kg00qf 5727 19 horses horse NNS cord-022526-j9kg00qf 5727 20 : : : cord-022526-j9kg00qf 5728 1 ten ten CD cord-022526-j9kg00qf 5728 2 cases case NNS cord-022526-j9kg00qf 5728 3 Review Review NNP cord-022526-j9kg00qf 5728 4 of of IN cord-022526-j9kg00qf 5728 5 115 115 CD cord-022526-j9kg00qf 5728 6 cases case NNS cord-022526-j9kg00qf 5728 7 of of IN cord-022526-j9kg00qf 5728 8 colic colic NN cord-022526-j9kg00qf 5728 9 in in IN cord-022526-j9kg00qf 5728 10 the the DT cord-022526-j9kg00qf 5728 11 pregnant pregnant JJ cord-022526-j9kg00qf 5728 12 mare mare NNP cord-022526-j9kg00qf 5728 13 Surgical surgical JJ cord-022526-j9kg00qf 5728 14 management management NN cord-022526-j9kg00qf 5728 15 of of IN cord-022526-j9kg00qf 5728 16 uterine uterine JJ cord-022526-j9kg00qf 5728 17 torsion torsion NN cord-022526-j9kg00qf 5728 18 in in IN cord-022526-j9kg00qf 5728 19 the the DT cord-022526-j9kg00qf 5728 20 mare mare NN cord-022526-j9kg00qf 5728 21 : : : cord-022526-j9kg00qf 5728 22 a a DT cord-022526-j9kg00qf 5728 23 review review NN cord-022526-j9kg00qf 5728 24 of of IN cord-022526-j9kg00qf 5728 25 26 26 CD cord-022526-j9kg00qf 5728 26 cases case NNS cord-022526-j9kg00qf 5728 27 Rabies rabie VBN cord-022526-j9kg00qf 5728 28 in in IN cord-022526-j9kg00qf 5728 29 horses horse NNS cord-022526-j9kg00qf 5728 30 : : : cord-022526-j9kg00qf 5728 31 21 21 CD cord-022526-j9kg00qf 5728 32 cases case NNS cord-022526-j9kg00qf 5728 33 Mechanisms mechanism NNS cord-022526-j9kg00qf 5728 34 of of IN cord-022526-j9kg00qf 5728 35 pain pain NN cord-022526-j9kg00qf 5728 36 and and CC cord-022526-j9kg00qf 5728 37 their -PRON- PRP$ cord-022526-j9kg00qf 5728 38 therapeutic therapeutic JJ cord-022526-j9kg00qf 5728 39 implications implication NNS cord-022526-j9kg00qf 5728 40 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5728 41 pharmacology pharmacology NN cord-022526-j9kg00qf 5729 1 Nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5729 2 anti anti JJ cord-022526-j9kg00qf 5729 3 - - JJ cord-022526-j9kg00qf 5729 4 inflammatory inflammatory JJ cord-022526-j9kg00qf 5729 5 drugs drug NNS cord-022526-j9kg00qf 5730 1 The the DT cord-022526-j9kg00qf 5730 2 role role NN cord-022526-j9kg00qf 5730 3 of of IN cord-022526-j9kg00qf 5730 4 cyclooxygenase cyclooxygenase NN cord-022526-j9kg00qf 5730 5 inhibitors inhibitor NNS cord-022526-j9kg00qf 5730 6 in in IN cord-022526-j9kg00qf 5730 7 repair repair NN cord-022526-j9kg00qf 5730 8 of of IN cord-022526-j9kg00qf 5730 9 ischaemic ischaemic NN cord-022526-j9kg00qf 5730 10 - - HYPH cord-022526-j9kg00qf 5730 11 injured injure VBN cord-022526-j9kg00qf 5730 12 jejunal jejunal JJ cord-022526-j9kg00qf 5730 13 mucosa mucosa NNP cord-022526-j9kg00qf 5730 14 in in IN cord-022526-j9kg00qf 5730 15 the the DT cord-022526-j9kg00qf 5730 16 horse horse NN cord-022526-j9kg00qf 5730 17 Alpha Alpha NNP cord-022526-j9kg00qf 5730 18 2 2 CD cord-022526-j9kg00qf 5730 19 adrenoceptor adrenoceptor NN cord-022526-j9kg00qf 5730 20 agonists agonist NNS cord-022526-j9kg00qf 5730 21 in in IN cord-022526-j9kg00qf 5730 22 the the DT cord-022526-j9kg00qf 5730 23 horse horse NN cord-022526-j9kg00qf 5730 24 : : : cord-022526-j9kg00qf 5730 25 a a DT cord-022526-j9kg00qf 5730 26 review review NN cord-022526-j9kg00qf 5730 27 Cardiovascular cardiovascular JJ cord-022526-j9kg00qf 5730 28 effects effect NNS cord-022526-j9kg00qf 5730 29 of of IN cord-022526-j9kg00qf 5730 30 medetomidine medetomidine NN cord-022526-j9kg00qf 5730 31 , , , cord-022526-j9kg00qf 5730 32 detomidine detomidine NNP cord-022526-j9kg00qf 5730 33 and and CC cord-022526-j9kg00qf 5730 34 xylazine xylazine NN cord-022526-j9kg00qf 5730 35 in in IN cord-022526-j9kg00qf 5730 36 horses horse NNS cord-022526-j9kg00qf 5730 37 Cardiovascular cardiovascular JJ cord-022526-j9kg00qf 5730 38 effects effect NNS cord-022526-j9kg00qf 5730 39 of of IN cord-022526-j9kg00qf 5730 40 xylazine xylazine NN cord-022526-j9kg00qf 5730 41 and and CC cord-022526-j9kg00qf 5730 42 detomidine detomidine NN cord-022526-j9kg00qf 5730 43 in in IN cord-022526-j9kg00qf 5730 44 horses horse NNS cord-022526-j9kg00qf 5730 45 Prognosis prognosis NN cord-022526-j9kg00qf 5730 46 in in IN cord-022526-j9kg00qf 5730 47 equine equine JJ cord-022526-j9kg00qf 5730 48 colic colic NN cord-022526-j9kg00qf 5730 49 : : : cord-022526-j9kg00qf 5730 50 a a DT cord-022526-j9kg00qf 5730 51 study study NN cord-022526-j9kg00qf 5730 52 of of IN cord-022526-j9kg00qf 5730 53 individual individual JJ cord-022526-j9kg00qf 5730 54 variables variable NNS cord-022526-j9kg00qf 5730 55 used use VBN cord-022526-j9kg00qf 5730 56 in in IN cord-022526-j9kg00qf 5730 57 case case NN cord-022526-j9kg00qf 5730 58 assessment assessment NN cord-022526-j9kg00qf 5730 59 A a NN cord-022526-j9kg00qf 5730 60 : : : cord-022526-j9kg00qf 5730 61 Study study NN cord-022526-j9kg00qf 5730 62 of of IN cord-022526-j9kg00qf 5730 63 variables variable NNS cord-022526-j9kg00qf 5730 64 commonly commonly RB cord-022526-j9kg00qf 5730 65 used use VBN cord-022526-j9kg00qf 5730 66 in in IN cord-022526-j9kg00qf 5730 67 examination examination NN cord-022526-j9kg00qf 5730 68 of of IN cord-022526-j9kg00qf 5730 69 equine equine JJ cord-022526-j9kg00qf 5730 70 colic colic NN cord-022526-j9kg00qf 5730 71 cases case NNS cord-022526-j9kg00qf 5730 72 to to TO cord-022526-j9kg00qf 5730 73 assess assess VB cord-022526-j9kg00qf 5730 74 prognostic prognostic JJ cord-022526-j9kg00qf 5730 75 value value NN cord-022526-j9kg00qf 5730 76 Clinical clinical JJ cord-022526-j9kg00qf 5730 77 evaluation evaluation NN cord-022526-j9kg00qf 5730 78 of of IN cord-022526-j9kg00qf 5730 79 blood blood NN cord-022526-j9kg00qf 5730 80 lactate lactate NN cord-022526-j9kg00qf 5730 81 levels level NNS cord-022526-j9kg00qf 5730 82 in in IN cord-022526-j9kg00qf 5730 83 equine equine JJ cord-022526-j9kg00qf 5730 84 colic colic NN cord-022526-j9kg00qf 5730 85 Use use NN cord-022526-j9kg00qf 5730 86 of of IN cord-022526-j9kg00qf 5730 87 clinical clinical JJ cord-022526-j9kg00qf 5730 88 pathology pathology NN cord-022526-j9kg00qf 5730 89 in in IN cord-022526-j9kg00qf 5730 90 evaluation evaluation NN cord-022526-j9kg00qf 5730 91 of of IN cord-022526-j9kg00qf 5730 92 horses horse NNS cord-022526-j9kg00qf 5730 93 with with IN cord-022526-j9kg00qf 5730 94 colic colic NN cord-022526-j9kg00qf 5731 1 The the DT cord-022526-j9kg00qf 5731 2 anion anion NN cord-022526-j9kg00qf 5731 3 gap gap NN cord-022526-j9kg00qf 5731 4 as as IN cord-022526-j9kg00qf 5731 5 a a DT cord-022526-j9kg00qf 5731 6 prognostic prognostic JJ cord-022526-j9kg00qf 5731 7 indicator indicator NN cord-022526-j9kg00qf 5731 8 in in IN cord-022526-j9kg00qf 5731 9 horses horse NNS cord-022526-j9kg00qf 5731 10 with with IN cord-022526-j9kg00qf 5731 11 abdominal abdominal JJ cord-022526-j9kg00qf 5731 12 pain pain NN cord-022526-j9kg00qf 5731 13 Strangulating strangulating JJ cord-022526-j9kg00qf 5731 14 volvulus volvulus NN cord-022526-j9kg00qf 5731 15 of of IN cord-022526-j9kg00qf 5731 16 the the DT cord-022526-j9kg00qf 5731 17 ascending ascend VBG cord-022526-j9kg00qf 5731 18 colon colon NN cord-022526-j9kg00qf 5731 19 in in IN cord-022526-j9kg00qf 5731 20 horses horse NNS cord-022526-j9kg00qf 5731 21 Diseases disease NNS cord-022526-j9kg00qf 5731 22 and and CC cord-022526-j9kg00qf 5731 23 surgery surgery NN cord-022526-j9kg00qf 5731 24 of of IN cord-022526-j9kg00qf 5731 25 the the DT cord-022526-j9kg00qf 5731 26 large large JJ cord-022526-j9kg00qf 5731 27 colon colon NN cord-022526-j9kg00qf 5731 28 Multivariable multivariable JJ cord-022526-j9kg00qf 5731 29 prediction prediction NN cord-022526-j9kg00qf 5731 30 model model NN cord-022526-j9kg00qf 5731 31 for for IN cord-022526-j9kg00qf 5731 32 the the DT cord-022526-j9kg00qf 5731 33 need need NN cord-022526-j9kg00qf 5731 34 for for IN cord-022526-j9kg00qf 5731 35 surgery surgery NN cord-022526-j9kg00qf 5731 36 in in IN cord-022526-j9kg00qf 5731 37 horses horse NNS cord-022526-j9kg00qf 5731 38 with with IN cord-022526-j9kg00qf 5731 39 colic colic NN cord-022526-j9kg00qf 5732 1 Prognosis prognosis NN cord-022526-j9kg00qf 5732 2 in in IN cord-022526-j9kg00qf 5732 3 equine equine JJ cord-022526-j9kg00qf 5732 4 colic colic NN cord-022526-j9kg00qf 5732 5 patients patient NNS cord-022526-j9kg00qf 5732 6 using use VBG cord-022526-j9kg00qf 5732 7 multivariable multivariable JJ cord-022526-j9kg00qf 5732 8 analysis analysis NN cord-022526-j9kg00qf 5732 9 Prognosis prognosis NN cord-022526-j9kg00qf 5732 10 in in IN cord-022526-j9kg00qf 5732 11 equine equine JJ cord-022526-j9kg00qf 5732 12 colic colic NN cord-022526-j9kg00qf 5732 13 : : : cord-022526-j9kg00qf 5732 14 a a DT cord-022526-j9kg00qf 5732 15 comparative comparative JJ cord-022526-j9kg00qf 5732 16 study study NN cord-022526-j9kg00qf 5732 17 of of IN cord-022526-j9kg00qf 5732 18 variables variable NNS cord-022526-j9kg00qf 5732 19 used use VBN cord-022526-j9kg00qf 5732 20 to to TO cord-022526-j9kg00qf 5732 21 assess assess VB cord-022526-j9kg00qf 5732 22 individual individual JJ cord-022526-j9kg00qf 5732 23 cases case NNS cord-022526-j9kg00qf 5733 1 Prognostic prognostic JJ cord-022526-j9kg00qf 5733 2 index index NN cord-022526-j9kg00qf 5733 3 for for IN cord-022526-j9kg00qf 5733 4 acute acute JJ cord-022526-j9kg00qf 5733 5 abdominal abdominal JJ cord-022526-j9kg00qf 5733 6 crisis crisis NN cord-022526-j9kg00qf 5733 7 ( ( -LRB- cord-022526-j9kg00qf 5733 8 colic colic NN cord-022526-j9kg00qf 5733 9 ) ) -RRB- cord-022526-j9kg00qf 5733 10 in in IN cord-022526-j9kg00qf 5733 11 horses horse NNS cord-022526-j9kg00qf 5733 12 Feeding feed VBG cord-022526-j9kg00qf 5733 13 and and CC cord-022526-j9kg00qf 5733 14 digestive digestive JJ cord-022526-j9kg00qf 5733 15 problems problem NNS cord-022526-j9kg00qf 5733 16 in in IN cord-022526-j9kg00qf 5733 17 horses horse NNS cord-022526-j9kg00qf 5733 18 : : : cord-022526-j9kg00qf 5733 19 physiologic physiologic JJ cord-022526-j9kg00qf 5733 20 responses response NNS cord-022526-j9kg00qf 5733 21 to to IN cord-022526-j9kg00qf 5733 22 a a DT cord-022526-j9kg00qf 5733 23 concentrated concentrated JJ cord-022526-j9kg00qf 5733 24 meal meal NN cord-022526-j9kg00qf 5733 25 Effect effect NN cord-022526-j9kg00qf 5733 26 of of IN cord-022526-j9kg00qf 5733 27 meal meal NN cord-022526-j9kg00qf 5733 28 feeding feeding NN cord-022526-j9kg00qf 5733 29 on on IN cord-022526-j9kg00qf 5733 30 plasma plasma NN cord-022526-j9kg00qf 5733 31 volume volume NN cord-022526-j9kg00qf 5733 32 and and CC cord-022526-j9kg00qf 5733 33 urinary urinary JJ cord-022526-j9kg00qf 5733 34 electrolyte electrolyte JJ cord-022526-j9kg00qf 5733 35 clearance clearance NN cord-022526-j9kg00qf 5733 36 in in IN cord-022526-j9kg00qf 5733 37 ponies pony NNS cord-022526-j9kg00qf 5733 38 Evaluation Evaluation NNP cord-022526-j9kg00qf 5733 39 of of IN cord-022526-j9kg00qf 5733 40 the the DT cord-022526-j9kg00qf 5733 41 microcirculation microcirculation NN cord-022526-j9kg00qf 5733 42 of of IN cord-022526-j9kg00qf 5733 43 the the DT cord-022526-j9kg00qf 5733 44 equine equine JJ cord-022526-j9kg00qf 5733 45 small small JJ cord-022526-j9kg00qf 5733 46 intestine intestine NN cord-022526-j9kg00qf 5733 47 after after IN cord-022526-j9kg00qf 5733 48 intraluminal intraluminal JJ cord-022526-j9kg00qf 5733 49 distention distention NN cord-022526-j9kg00qf 5733 50 and and CC cord-022526-j9kg00qf 5733 51 subsequent subsequent JJ cord-022526-j9kg00qf 5733 52 decompression decompression NN cord-022526-j9kg00qf 5733 53 Morphologic morphologic JJ cord-022526-j9kg00qf 5733 54 effects effect NNS cord-022526-j9kg00qf 5733 55 of of IN cord-022526-j9kg00qf 5733 56 experimental experimental JJ cord-022526-j9kg00qf 5733 57 distention distention NN cord-022526-j9kg00qf 5733 58 of of IN cord-022526-j9kg00qf 5733 59 equine equine JJ cord-022526-j9kg00qf 5733 60 small small JJ cord-022526-j9kg00qf 5733 61 intestine intestine NN cord-022526-j9kg00qf 5733 62 Surgical surgical JJ cord-022526-j9kg00qf 5733 63 reduction reduction NN cord-022526-j9kg00qf 5733 64 of of IN cord-022526-j9kg00qf 5733 65 ileal ileal JJ cord-022526-j9kg00qf 5733 66 impactions impaction NNS cord-022526-j9kg00qf 5733 67 in in IN cord-022526-j9kg00qf 5733 68 the the DT cord-022526-j9kg00qf 5733 69 horse horse NN cord-022526-j9kg00qf 5733 70 : : : cord-022526-j9kg00qf 5733 71 28 28 CD cord-022526-j9kg00qf 5733 72 cases case NNS cord-022526-j9kg00qf 5733 73 Medical medical JJ cord-022526-j9kg00qf 5733 74 treatment treatment NN cord-022526-j9kg00qf 5733 75 of of IN cord-022526-j9kg00qf 5733 76 horses horse NNS cord-022526-j9kg00qf 5733 77 with with IN cord-022526-j9kg00qf 5733 78 ileal ileal JJ cord-022526-j9kg00qf 5733 79 impactions impaction NNS cord-022526-j9kg00qf 5733 80 : : : cord-022526-j9kg00qf 5733 81 10 10 CD cord-022526-j9kg00qf 5733 82 cases case NNS cord-022526-j9kg00qf 5734 1 Ascarids Ascarids NNP cord-022526-j9kg00qf 5734 2 : : : cord-022526-j9kg00qf 5734 3 recent recent JJ cord-022526-j9kg00qf 5734 4 advances advance NNS cord-022526-j9kg00qf 5734 5 The the DT cord-022526-j9kg00qf 5734 6 purported purported JJ cord-022526-j9kg00qf 5734 7 role role NN cord-022526-j9kg00qf 5734 8 of of IN cord-022526-j9kg00qf 5734 9 coastal coastal JJ cord-022526-j9kg00qf 5734 10 Bermuda Bermuda NNP cord-022526-j9kg00qf 5734 11 hay hay NN cord-022526-j9kg00qf 5734 12 in in IN cord-022526-j9kg00qf 5734 13 the the DT cord-022526-j9kg00qf 5734 14 etiology etiology NN cord-022526-j9kg00qf 5734 15 of of IN cord-022526-j9kg00qf 5734 16 ileal ileal JJ cord-022526-j9kg00qf 5734 17 impactions impaction NNS cord-022526-j9kg00qf 5734 18 : : : cord-022526-j9kg00qf 5734 19 results result NNS cord-022526-j9kg00qf 5734 20 of of IN cord-022526-j9kg00qf 5734 21 a a DT cord-022526-j9kg00qf 5734 22 questionnaire questionnaire NN cord-022526-j9kg00qf 5734 23 ( ( -LRB- cord-022526-j9kg00qf 5734 24 abstract abstract JJ cord-022526-j9kg00qf 5734 25 ) ) -RRB- cord-022526-j9kg00qf 5734 26 Tapeworm tapeworm NN cord-022526-j9kg00qf 5734 27 infection infection NN cord-022526-j9kg00qf 5734 28 is be VBZ cord-022526-j9kg00qf 5734 29 a a DT cord-022526-j9kg00qf 5734 30 significant significant JJ cord-022526-j9kg00qf 5734 31 risk risk NN cord-022526-j9kg00qf 5734 32 factor factor NN cord-022526-j9kg00qf 5734 33 for for IN cord-022526-j9kg00qf 5734 34 spasmodic spasmodic JJ cord-022526-j9kg00qf 5734 35 colic colic NN cord-022526-j9kg00qf 5734 36 and and CC cord-022526-j9kg00qf 5734 37 ileal ileal JJ cord-022526-j9kg00qf 5734 38 impaction impaction NN cord-022526-j9kg00qf 5734 39 colic colic NN cord-022526-j9kg00qf 5734 40 in in IN cord-022526-j9kg00qf 5734 41 the the DT cord-022526-j9kg00qf 5734 42 horse horse NN cord-022526-j9kg00qf 5734 43 Use use NN cord-022526-j9kg00qf 5734 44 of of IN cord-022526-j9kg00qf 5734 45 excretory excretory JJ cord-022526-j9kg00qf 5734 46 / / SYM cord-022526-j9kg00qf 5734 47 secretory secretory JJ cord-022526-j9kg00qf 5734 48 antigens antigen NNS cord-022526-j9kg00qf 5734 49 for for IN cord-022526-j9kg00qf 5734 50 the the DT cord-022526-j9kg00qf 5734 51 serodiagnosis serodiagnosis NN cord-022526-j9kg00qf 5734 52 of of IN cord-022526-j9kg00qf 5734 53 Anoplocephala Anoplocephala NNP cord-022526-j9kg00qf 5734 54 perfoliata perfoliata NN cord-022526-j9kg00qf 5734 55 cestodosis cestodosis NN cord-022526-j9kg00qf 5734 56 Ileal Ileal NNP cord-022526-j9kg00qf 5734 57 impaction impaction NN cord-022526-j9kg00qf 5734 58 in in IN cord-022526-j9kg00qf 5734 59 the the DT cord-022526-j9kg00qf 5734 60 horse horse NN cord-022526-j9kg00qf 5734 61 : : : cord-022526-j9kg00qf 5735 1 75 75 CD cord-022526-j9kg00qf 5735 2 cases case NNS cord-022526-j9kg00qf 5735 3 Evaluation Evaluation NNP cord-022526-j9kg00qf 5735 4 of of IN cord-022526-j9kg00qf 5735 5 factors factor NNS cord-022526-j9kg00qf 5735 6 associated associate VBN cord-022526-j9kg00qf 5735 7 with with IN cord-022526-j9kg00qf 5735 8 postoperative postoperative JJ cord-022526-j9kg00qf 5735 9 ileus ileus NN cord-022526-j9kg00qf 5735 10 in in IN cord-022526-j9kg00qf 5735 11 horses horse NNS cord-022526-j9kg00qf 5735 12 : : : cord-022526-j9kg00qf 5735 13 31 31 CD cord-022526-j9kg00qf 5735 14 cases case NNS cord-022526-j9kg00qf 5736 1 Idiopathic idiopathic JJ cord-022526-j9kg00qf 5736 2 muscular muscular JJ cord-022526-j9kg00qf 5736 3 hypertrophy hypertrophy NN cord-022526-j9kg00qf 5736 4 of of IN cord-022526-j9kg00qf 5736 5 the the DT cord-022526-j9kg00qf 5736 6 equine equine JJ cord-022526-j9kg00qf 5736 7 small small JJ cord-022526-j9kg00qf 5736 8 intestine intestine NN cord-022526-j9kg00qf 5736 9 : : : cord-022526-j9kg00qf 5736 10 11 11 CD cord-022526-j9kg00qf 5736 11 cases case NNS cord-022526-j9kg00qf 5736 12 ( ( -LRB- cord-022526-j9kg00qf 5736 13 1980 1980 CD cord-022526-j9kg00qf 5736 14 - - SYM cord-022526-j9kg00qf 5736 15 1991 1991 CD cord-022526-j9kg00qf 5736 16 ) ) -RRB- cord-022526-j9kg00qf 5736 17 Obstruction obstruction NN cord-022526-j9kg00qf 5736 18 of of IN cord-022526-j9kg00qf 5736 19 the the DT cord-022526-j9kg00qf 5736 20 ileum ileum NN cord-022526-j9kg00qf 5736 21 in in IN cord-022526-j9kg00qf 5736 22 the the DT cord-022526-j9kg00qf 5736 23 horse horse NN cord-022526-j9kg00qf 5736 24 : : : cord-022526-j9kg00qf 5736 25 a a DT cord-022526-j9kg00qf 5736 26 report report NN cord-022526-j9kg00qf 5736 27 of of IN cord-022526-j9kg00qf 5736 28 27 27 CD cord-022526-j9kg00qf 5736 29 clinical clinical JJ cord-022526-j9kg00qf 5736 30 cases case NNS cord-022526-j9kg00qf 5737 1 Ileal ileal NN cord-022526-j9kg00qf 5737 2 muscular muscular JJ cord-022526-j9kg00qf 5737 3 hypertrophy hypertrophy NN cord-022526-j9kg00qf 5737 4 and and CC cord-022526-j9kg00qf 5737 5 rupture rupture NN cord-022526-j9kg00qf 5737 6 in in IN cord-022526-j9kg00qf 5737 7 a a DT cord-022526-j9kg00qf 5737 8 pony pony NN cord-022526-j9kg00qf 5737 9 three three CD cord-022526-j9kg00qf 5737 10 years year NNS cord-022526-j9kg00qf 5737 11 after after IN cord-022526-j9kg00qf 5737 12 surgery surgery NN cord-022526-j9kg00qf 5737 13 for for IN cord-022526-j9kg00qf 5737 14 ileocaecal ileocaecal JJ cord-022526-j9kg00qf 5737 15 intussusception intussusception NN cord-022526-j9kg00qf 5737 16 Jejunocolostomy Jejunocolostomy NNP cord-022526-j9kg00qf 5737 17 or or CC cord-022526-j9kg00qf 5737 18 ileocolostomy ileocolostomy NN cord-022526-j9kg00qf 5737 19 for for IN cord-022526-j9kg00qf 5737 20 treatment treatment NN cord-022526-j9kg00qf 5737 21 of of IN cord-022526-j9kg00qf 5737 22 cecal cecal JJ cord-022526-j9kg00qf 5737 23 impaction impaction NN cord-022526-j9kg00qf 5737 24 in in IN cord-022526-j9kg00qf 5737 25 horses horse NNS cord-022526-j9kg00qf 5737 26 : : : cord-022526-j9kg00qf 5737 27 nine nine CD cord-022526-j9kg00qf 5737 28 cases case NNS cord-022526-j9kg00qf 5737 29 ( ( -LRB- cord-022526-j9kg00qf 5737 30 1985 1985 CD cord-022526-j9kg00qf 5737 31 - - SYM cord-022526-j9kg00qf 5737 32 1995 1995 CD cord-022526-j9kg00qf 5737 33 ) ) -RRB- cord-022526-j9kg00qf 5738 1 Small small JJ cord-022526-j9kg00qf 5738 2 intestinal intestinal JJ cord-022526-j9kg00qf 5738 3 strangulation strangulation NN cord-022526-j9kg00qf 5738 4 caused cause VBN cord-022526-j9kg00qf 5738 5 by by IN cord-022526-j9kg00qf 5738 6 Meckel Meckel NNP cord-022526-j9kg00qf 5738 7 's 's POS cord-022526-j9kg00qf 5738 8 diverticulum diverticulum NN cord-022526-j9kg00qf 5738 9 in in IN cord-022526-j9kg00qf 5738 10 a a DT cord-022526-j9kg00qf 5738 11 horse horse NN cord-022526-j9kg00qf 5738 12 Volvulus Volvulus NNP cord-022526-j9kg00qf 5738 13 associated associate VBN cord-022526-j9kg00qf 5738 14 with with IN cord-022526-j9kg00qf 5738 15 Meckel Meckel NNP cord-022526-j9kg00qf 5738 16 's 's POS cord-022526-j9kg00qf 5738 17 diverticulum diverticulum NN cord-022526-j9kg00qf 5738 18 in in IN cord-022526-j9kg00qf 5738 19 the the DT cord-022526-j9kg00qf 5738 20 horse horse NN cord-022526-j9kg00qf 5738 21 Congenital congenital JJ cord-022526-j9kg00qf 5738 22 jejunal jejunal JJ cord-022526-j9kg00qf 5738 23 diverticulum diverticulum NN cord-022526-j9kg00qf 5738 24 in in IN cord-022526-j9kg00qf 5738 25 a a DT cord-022526-j9kg00qf 5738 26 foal foal NN cord-022526-j9kg00qf 5738 27 Mesodiverticular Mesodiverticular NNP cord-022526-j9kg00qf 5738 28 bands band NNS cord-022526-j9kg00qf 5738 29 as as IN cord-022526-j9kg00qf 5738 30 a a DT cord-022526-j9kg00qf 5738 31 cause cause NN cord-022526-j9kg00qf 5738 32 of of IN cord-022526-j9kg00qf 5738 33 small small JJ cord-022526-j9kg00qf 5738 34 intestinal intestinal JJ cord-022526-j9kg00qf 5738 35 strangulation strangulation NN cord-022526-j9kg00qf 5738 36 and and CC cord-022526-j9kg00qf 5738 37 volvulus volvulus NN cord-022526-j9kg00qf 5738 38 in in IN cord-022526-j9kg00qf 5738 39 the the DT cord-022526-j9kg00qf 5738 40 horse horse NN cord-022526-j9kg00qf 5738 41 Abdominal abdominal JJ cord-022526-j9kg00qf 5738 42 adhesions adhesion NNS cord-022526-j9kg00qf 5738 43 after after IN cord-022526-j9kg00qf 5738 44 small small JJ cord-022526-j9kg00qf 5738 45 intestinal intestinal JJ cord-022526-j9kg00qf 5738 46 surgery surgery NN cord-022526-j9kg00qf 5738 47 in in IN cord-022526-j9kg00qf 5738 48 the the DT cord-022526-j9kg00qf 5738 49 horse horse NN cord-022526-j9kg00qf 5738 50 Induction Induction NNP cord-022526-j9kg00qf 5738 51 of of IN cord-022526-j9kg00qf 5738 52 peritoneal peritoneal JJ cord-022526-j9kg00qf 5738 53 adhesions adhesion NNS cord-022526-j9kg00qf 5738 54 with with IN cord-022526-j9kg00qf 5738 55 small small JJ cord-022526-j9kg00qf 5738 56 intestinal intestinal JJ cord-022526-j9kg00qf 5738 57 ischaemia ischaemia NN cord-022526-j9kg00qf 5738 58 and and CC cord-022526-j9kg00qf 5738 59 distention distention NN cord-022526-j9kg00qf 5738 60 in in IN cord-022526-j9kg00qf 5738 61 the the DT cord-022526-j9kg00qf 5738 62 foal foal NN cord-022526-j9kg00qf 5739 1 The the DT cord-022526-j9kg00qf 5739 2 characteristics characteristic NNS cord-022526-j9kg00qf 5739 3 of of IN cord-022526-j9kg00qf 5739 4 intestinal intestinal JJ cord-022526-j9kg00qf 5739 5 injury injury NN cord-022526-j9kg00qf 5739 6 peripheral peripheral JJ cord-022526-j9kg00qf 5739 7 to to IN cord-022526-j9kg00qf 5739 8 strangulating strangulating JJ cord-022526-j9kg00qf 5739 9 obstruction obstruction NN cord-022526-j9kg00qf 5739 10 lesions lesion NNS cord-022526-j9kg00qf 5739 11 in in IN cord-022526-j9kg00qf 5739 12 the the DT cord-022526-j9kg00qf 5739 13 equine equine JJ cord-022526-j9kg00qf 5739 14 small small JJ cord-022526-j9kg00qf 5739 15 intestine intestine NN cord-022526-j9kg00qf 5739 16 Current current JJ cord-022526-j9kg00qf 5739 17 concepts concept NNS cord-022526-j9kg00qf 5739 18 in in IN cord-022526-j9kg00qf 5739 19 management management NN cord-022526-j9kg00qf 5739 20 of of IN cord-022526-j9kg00qf 5739 21 abdominal abdominal JJ cord-022526-j9kg00qf 5739 22 adhesions adhesion NNS cord-022526-j9kg00qf 5740 1 One one CD cord-022526-j9kg00qf 5740 2 percent percent NN cord-022526-j9kg00qf 5740 3 sodium sodium NN cord-022526-j9kg00qf 5740 4 carboxymethylcellulose carboxymethylcellulose NNP cord-022526-j9kg00qf 5740 5 prevents prevent VBZ cord-022526-j9kg00qf 5740 6 experimentally experimentally RB cord-022526-j9kg00qf 5740 7 induced induce VBN cord-022526-j9kg00qf 5740 8 abdominal abdominal JJ cord-022526-j9kg00qf 5740 9 adhesions adhesion NNS cord-022526-j9kg00qf 5740 10 in in IN cord-022526-j9kg00qf 5740 11 horses horse NNS cord-022526-j9kg00qf 5740 12 Effect Effect NNP cord-022526-j9kg00qf 5740 13 of of IN cord-022526-j9kg00qf 5740 14 carboxymethylcellulose carboxymethylcellulose NN cord-022526-j9kg00qf 5740 15 and and CC cord-022526-j9kg00qf 5740 16 a a DT cord-022526-j9kg00qf 5740 17 hyaluronate hyaluronate NN cord-022526-j9kg00qf 5740 18 - - HYPH cord-022526-j9kg00qf 5740 19 carboxymethylcellulose carboxymethylcellulose NN cord-022526-j9kg00qf 5740 20 membrane membrane NN cord-022526-j9kg00qf 5740 21 on on IN cord-022526-j9kg00qf 5740 22 healing healing NN cord-022526-j9kg00qf 5740 23 of of IN cord-022526-j9kg00qf 5740 24 intestinal intestinal JJ cord-022526-j9kg00qf 5740 25 anastomoses anastomosis NNS cord-022526-j9kg00qf 5740 26 in in IN cord-022526-j9kg00qf 5740 27 horses horse NNS cord-022526-j9kg00qf 5741 1 Intraperitoneal intraperitoneal JJ cord-022526-j9kg00qf 5741 2 use use NN cord-022526-j9kg00qf 5741 3 of of IN cord-022526-j9kg00qf 5741 4 sodium sodium NN cord-022526-j9kg00qf 5741 5 carboxymethylcellulose carboxymethylcellulose NN cord-022526-j9kg00qf 5741 6 in in IN cord-022526-j9kg00qf 5741 7 horses horse NNS cord-022526-j9kg00qf 5741 8 undergoing undergo VBG cord-022526-j9kg00qf 5741 9 exploratory exploratory JJ cord-022526-j9kg00qf 5741 10 celiotomy celiotomy NN cord-022526-j9kg00qf 5741 11 Prevention Prevention NNP cord-022526-j9kg00qf 5741 12 of of IN cord-022526-j9kg00qf 5741 13 intraabdominal intraabdominal JJ cord-022526-j9kg00qf 5741 14 adhesions adhesion NNS cord-022526-j9kg00qf 5741 15 in in IN cord-022526-j9kg00qf 5741 16 ponies pony NNS cord-022526-j9kg00qf 5741 17 by by IN cord-022526-j9kg00qf 5741 18 low low JJ cord-022526-j9kg00qf 5741 19 - - HYPH cord-022526-j9kg00qf 5741 20 dose dose NN cord-022526-j9kg00qf 5741 21 heparin heparin NN cord-022526-j9kg00qf 5741 22 therapy therapy NN cord-022526-j9kg00qf 5741 23 Retrospective Retrospective NNP cord-022526-j9kg00qf 5741 24 analysis analysis NN cord-022526-j9kg00qf 5741 25 of of IN cord-022526-j9kg00qf 5741 26 the the DT cord-022526-j9kg00qf 5741 27 results result NNS cord-022526-j9kg00qf 5741 28 of of IN cord-022526-j9kg00qf 5741 29 151 151 CD cord-022526-j9kg00qf 5741 30 exploratory exploratory JJ cord-022526-j9kg00qf 5741 31 laparotomies laparotomy NNS cord-022526-j9kg00qf 5741 32 in in IN cord-022526-j9kg00qf 5741 33 horses horse NNS cord-022526-j9kg00qf 5741 34 with with IN cord-022526-j9kg00qf 5741 35 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5741 36 disease disease NN cord-022526-j9kg00qf 5741 37 Surgical surgical JJ cord-022526-j9kg00qf 5741 38 treatment treatment NN cord-022526-j9kg00qf 5741 39 for for IN cord-022526-j9kg00qf 5741 40 colic colic NN cord-022526-j9kg00qf 5741 41 in in IN cord-022526-j9kg00qf 5741 42 the the DT cord-022526-j9kg00qf 5741 43 foal foal NN cord-022526-j9kg00qf 5741 44 Retrospective retrospective JJ cord-022526-j9kg00qf 5741 45 evaluation evaluation NN cord-022526-j9kg00qf 5741 46 of of IN cord-022526-j9kg00qf 5741 47 repeat repeat NN cord-022526-j9kg00qf 5741 48 celiotomy celiotomy NN cord-022526-j9kg00qf 5741 49 in in IN cord-022526-j9kg00qf 5741 50 53 53 CD cord-022526-j9kg00qf 5741 51 horses horse NNS cord-022526-j9kg00qf 5741 52 with with IN cord-022526-j9kg00qf 5741 53 acute acute JJ cord-022526-j9kg00qf 5741 54 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5741 55 disease disease NN cord-022526-j9kg00qf 5741 56 Risk risk NN cord-022526-j9kg00qf 5741 57 factors factor NNS cord-022526-j9kg00qf 5741 58 for for IN cord-022526-j9kg00qf 5741 59 reduced reduced JJ cord-022526-j9kg00qf 5741 60 postoperative postoperative JJ cord-022526-j9kg00qf 5741 61 fecal fecal JJ cord-022526-j9kg00qf 5741 62 output output NN cord-022526-j9kg00qf 5741 63 in in IN cord-022526-j9kg00qf 5741 64 horses horse NNS cord-022526-j9kg00qf 5741 65 : : : cord-022526-j9kg00qf 5741 66 37 37 CD cord-022526-j9kg00qf 5741 67 cases case NNS cord-022526-j9kg00qf 5741 68 ( ( -LRB- cord-022526-j9kg00qf 5741 69 1997 1997 CD cord-022526-j9kg00qf 5741 70 - - SYM cord-022526-j9kg00qf 5741 71 1998 1998 CD cord-022526-j9kg00qf 5741 72 ) ) -RRB- cord-022526-j9kg00qf 5742 1 Role role NN cord-022526-j9kg00qf 5742 2 of of IN cord-022526-j9kg00qf 5742 3 inducible inducible JJ cord-022526-j9kg00qf 5742 4 nitric nitric NN cord-022526-j9kg00qf 5742 5 oxide oxide NN cord-022526-j9kg00qf 5742 6 synthase synthase NN cord-022526-j9kg00qf 5742 7 in in IN cord-022526-j9kg00qf 5742 8 postoperative postoperative JJ cord-022526-j9kg00qf 5742 9 intestinal intestinal JJ cord-022526-j9kg00qf 5742 10 smooth smooth JJ cord-022526-j9kg00qf 5742 11 muscle muscle NN cord-022526-j9kg00qf 5742 12 dysfunction dysfunction NN cord-022526-j9kg00qf 5742 13 in in IN cord-022526-j9kg00qf 5742 14 rodents rodent NNS cord-022526-j9kg00qf 5742 15 Surgically surgically RB cord-022526-j9kg00qf 5742 16 induced induce VBN cord-022526-j9kg00qf 5742 17 leukocytic leukocytic JJ cord-022526-j9kg00qf 5742 18 infiltrates infiltrate VBZ cord-022526-j9kg00qf 5742 19 within within IN cord-022526-j9kg00qf 5742 20 the the DT cord-022526-j9kg00qf 5742 21 rat rat NN cord-022526-j9kg00qf 5742 22 intestinal intestinal JJ cord-022526-j9kg00qf 5742 23 muscularis muscularis NNP cord-022526-j9kg00qf 5742 24 mediate mediate VB cord-022526-j9kg00qf 5742 25 postoperative postoperative JJ cord-022526-j9kg00qf 5742 26 ileus ileus NN cord-022526-j9kg00qf 5742 27 Surgical surgical JJ cord-022526-j9kg00qf 5742 28 manipulation manipulation NN cord-022526-j9kg00qf 5742 29 of of IN cord-022526-j9kg00qf 5742 30 the the DT cord-022526-j9kg00qf 5742 31 gut gut NN cord-022526-j9kg00qf 5742 32 elicits elicit VBZ cord-022526-j9kg00qf 5742 33 an an DT cord-022526-j9kg00qf 5742 34 intestinal intestinal JJ cord-022526-j9kg00qf 5742 35 muscularis muscularis JJ cord-022526-j9kg00qf 5742 36 inflammatory inflammatory JJ cord-022526-j9kg00qf 5742 37 response response NN cord-022526-j9kg00qf 5742 38 resulting result VBG cord-022526-j9kg00qf 5742 39 in in IN cord-022526-j9kg00qf 5742 40 postsurgical postsurgical JJ cord-022526-j9kg00qf 5742 41 ileus ileus NNP cord-022526-j9kg00qf 5742 42 Pathophysiology Pathophysiology NNP cord-022526-j9kg00qf 5742 43 of of IN cord-022526-j9kg00qf 5742 44 equine equine JJ cord-022526-j9kg00qf 5742 45 postoperative postoperative JJ cord-022526-j9kg00qf 5742 46 ileus ileus NN cord-022526-j9kg00qf 5742 47 : : : cord-022526-j9kg00qf 5742 48 effect effect NN cord-022526-j9kg00qf 5742 49 of of IN cord-022526-j9kg00qf 5742 50 adrenergic adrenergic JJ cord-022526-j9kg00qf 5742 51 blockade blockade NN cord-022526-j9kg00qf 5742 52 , , , cord-022526-j9kg00qf 5742 53 parasympathetic parasympathetic JJ cord-022526-j9kg00qf 5742 54 stimulation stimulation NN cord-022526-j9kg00qf 5742 55 and and CC cord-022526-j9kg00qf 5742 56 metoclopramide metoclopramide NN cord-022526-j9kg00qf 5742 57 in in IN cord-022526-j9kg00qf 5742 58 an an DT cord-022526-j9kg00qf 5742 59 experimental experimental JJ cord-022526-j9kg00qf 5742 60 model model NN cord-022526-j9kg00qf 5743 1 The the DT cord-022526-j9kg00qf 5743 2 effect effect NN cord-022526-j9kg00qf 5743 3 of of IN cord-022526-j9kg00qf 5743 4 prostaglandin prostaglandin NN cord-022526-j9kg00qf 5743 5 E1 e1 NN cord-022526-j9kg00qf 5743 6 on on IN cord-022526-j9kg00qf 5743 7 motility motility NN cord-022526-j9kg00qf 5743 8 of of IN cord-022526-j9kg00qf 5743 9 the the DT cord-022526-j9kg00qf 5743 10 equine equine JJ cord-022526-j9kg00qf 5743 11 gut gut NN cord-022526-j9kg00qf 5744 1 In in IN cord-022526-j9kg00qf 5744 2 vitro vitro FW cord-022526-j9kg00qf 5744 3 investigation investigation NN cord-022526-j9kg00qf 5744 4 of of IN cord-022526-j9kg00qf 5744 5 the the DT cord-022526-j9kg00qf 5744 6 effect effect NN cord-022526-j9kg00qf 5744 7 of of IN cord-022526-j9kg00qf 5744 8 prostaglandins prostaglandin NNS cord-022526-j9kg00qf 5744 9 and and CC cord-022526-j9kg00qf 5744 10 nonsteroidal nonsteroidal JJ cord-022526-j9kg00qf 5744 11 antiinflammatory antiinflammatory JJ cord-022526-j9kg00qf 5744 12 drugs drug NNS cord-022526-j9kg00qf 5744 13 on on IN cord-022526-j9kg00qf 5744 14 contractile contractile JJ cord-022526-j9kg00qf 5744 15 activity activity NN cord-022526-j9kg00qf 5744 16 of of IN cord-022526-j9kg00qf 5744 17 the the DT cord-022526-j9kg00qf 5744 18 equine equine JJ cord-022526-j9kg00qf 5744 19 smooth smooth JJ cord-022526-j9kg00qf 5744 20 muscle muscle NN cord-022526-j9kg00qf 5744 21 of of IN cord-022526-j9kg00qf 5744 22 the the DT cord-022526-j9kg00qf 5744 23 dorsal dorsal JJ cord-022526-j9kg00qf 5744 24 colon colon NN cord-022526-j9kg00qf 5744 25 , , , cord-022526-j9kg00qf 5744 26 ventral ventral JJ cord-022526-j9kg00qf 5744 27 colon colon NN cord-022526-j9kg00qf 5744 28 , , , cord-022526-j9kg00qf 5744 29 and and CC cord-022526-j9kg00qf 5744 30 pelvic pelvic JJ cord-022526-j9kg00qf 5744 31 flexure flexure NN cord-022526-j9kg00qf 5744 32 Evaluation evaluation NN cord-022526-j9kg00qf 5744 33 of of IN cord-022526-j9kg00qf 5744 34 nitric nitric NN cord-022526-j9kg00qf 5744 35 oxide oxide NN cord-022526-j9kg00qf 5744 36 as as IN cord-022526-j9kg00qf 5744 37 an an DT cord-022526-j9kg00qf 5744 38 inhibitory inhibitory JJ cord-022526-j9kg00qf 5744 39 neurotransmitter neurotransmitter NN cord-022526-j9kg00qf 5744 40 in in IN cord-022526-j9kg00qf 5744 41 the the DT cord-022526-j9kg00qf 5744 42 equine equine JJ cord-022526-j9kg00qf 5744 43 ventral ventral JJ cord-022526-j9kg00qf 5744 44 colon colon NN cord-022526-j9kg00qf 5744 45 Prostanoid Prostanoid NNP cord-022526-j9kg00qf 5744 46 production production NN cord-022526-j9kg00qf 5744 47 via via IN cord-022526-j9kg00qf 5744 48 COX-2 COX-2 NNP cord-022526-j9kg00qf 5744 49 as as IN cord-022526-j9kg00qf 5744 50 a a DT cord-022526-j9kg00qf 5744 51 causative causative JJ cord-022526-j9kg00qf 5744 52 mechanism mechanism NN cord-022526-j9kg00qf 5744 53 of of IN cord-022526-j9kg00qf 5744 54 rodent rodent NN cord-022526-j9kg00qf 5744 55 postoperative postoperative JJ cord-022526-j9kg00qf 5744 56 ileus ileus NNP cord-022526-j9kg00qf 5745 1 The the DT cord-022526-j9kg00qf 5745 2 action action NN cord-022526-j9kg00qf 5745 3 of of IN cord-022526-j9kg00qf 5745 4 low low JJ cord-022526-j9kg00qf 5745 5 dose dose NN cord-022526-j9kg00qf 5745 6 endotoxin endotoxin NN cord-022526-j9kg00qf 5745 7 on on IN cord-022526-j9kg00qf 5745 8 equine equine JJ cord-022526-j9kg00qf 5745 9 bowel bowel NN cord-022526-j9kg00qf 5745 10 motility motility NN cord-022526-j9kg00qf 5745 11 Sir Sir NNP cord-022526-j9kg00qf 5745 12 Frederick Frederick NNP cord-022526-j9kg00qf 5745 13 Hobday Hobday NNP cord-022526-j9kg00qf 5745 14 Memorial Memorial NNP cord-022526-j9kg00qf 5745 15 Lecture Lecture NNP cord-022526-j9kg00qf 5745 16 : : : cord-022526-j9kg00qf 5745 17 all all DT cord-022526-j9kg00qf 5745 18 wind wind NN cord-022526-j9kg00qf 5745 19 and and CC cord-022526-j9kg00qf 5745 20 water water NN cord-022526-j9kg00qf 5745 21 - - HYPH cord-022526-j9kg00qf 5745 22 some some DT cord-022526-j9kg00qf 5745 23 progress progress NN cord-022526-j9kg00qf 5745 24 in in IN cord-022526-j9kg00qf 5745 25 the the DT cord-022526-j9kg00qf 5745 26 study study NN cord-022526-j9kg00qf 5745 27 of of IN cord-022526-j9kg00qf 5745 28 equine equine JJ cord-022526-j9kg00qf 5745 29 gut gut NN cord-022526-j9kg00qf 5745 30 motility motility NN cord-022526-j9kg00qf 5745 31 Antagonism antagonism NN cord-022526-j9kg00qf 5745 32 of of IN cord-022526-j9kg00qf 5745 33 endotoxin endotoxin NN cord-022526-j9kg00qf 5745 34 - - HYPH cord-022526-j9kg00qf 5745 35 induced induce VBN cord-022526-j9kg00qf 5745 36 disruption disruption NN cord-022526-j9kg00qf 5745 37 of of IN cord-022526-j9kg00qf 5745 38 equine equine JJ cord-022526-j9kg00qf 5745 39 bowel bowel NN cord-022526-j9kg00qf 5745 40 motility motility NN cord-022526-j9kg00qf 5745 41 by by IN cord-022526-j9kg00qf 5745 42 flunixin flunixin NNP cord-022526-j9kg00qf 5745 43 and and CC cord-022526-j9kg00qf 5745 44 phenylbutazone phenylbutazone NNP cord-022526-j9kg00qf 5745 45 Cyclooxygenase Cyclooxygenase NNP cord-022526-j9kg00qf 5745 46 inhibitors inhibitor NNS cord-022526-j9kg00qf 5745 47 in in IN cord-022526-j9kg00qf 5745 48 equine equine JJ cord-022526-j9kg00qf 5745 49 practice practice NN cord-022526-j9kg00qf 5746 1 In in IN cord-022526-j9kg00qf 5746 2 vitro vitro FW cord-022526-j9kg00qf 5746 3 effects effect NNS cord-022526-j9kg00qf 5746 4 of of IN cord-022526-j9kg00qf 5746 5 erythromycin erythromycin NN cord-022526-j9kg00qf 5746 6 , , , cord-022526-j9kg00qf 5746 7 lidocaine lidocaine NN cord-022526-j9kg00qf 5746 8 , , , cord-022526-j9kg00qf 5746 9 and and CC cord-022526-j9kg00qf 5746 10 metoclopramide metoclopramide NN cord-022526-j9kg00qf 5746 11 on on IN cord-022526-j9kg00qf 5746 12 smooth smooth JJ cord-022526-j9kg00qf 5746 13 muscle muscle NN cord-022526-j9kg00qf 5746 14 from from IN cord-022526-j9kg00qf 5746 15 the the DT cord-022526-j9kg00qf 5746 16 pyloric pyloric JJ cord-022526-j9kg00qf 5746 17 antrum antrum NN cord-022526-j9kg00qf 5746 18 , , , cord-022526-j9kg00qf 5746 19 proximal proximal JJ cord-022526-j9kg00qf 5746 20 portion portion NN cord-022526-j9kg00qf 5746 21 of of IN cord-022526-j9kg00qf 5746 22 the the DT cord-022526-j9kg00qf 5746 23 duodenum duodenum NN cord-022526-j9kg00qf 5746 24 , , , cord-022526-j9kg00qf 5746 25 and and CC cord-022526-j9kg00qf 5746 26 middle middle JJ cord-022526-j9kg00qf 5746 27 portion portion NN cord-022526-j9kg00qf 5746 28 of of IN cord-022526-j9kg00qf 5746 29 the the DT cord-022526-j9kg00qf 5746 30 jejunum jejunum NNS cord-022526-j9kg00qf 5746 31 of of IN cord-022526-j9kg00qf 5746 32 horses horse NNS cord-022526-j9kg00qf 5746 33 Efficacy Efficacy NNP cord-022526-j9kg00qf 5746 34 of of IN cord-022526-j9kg00qf 5746 35 metoclopramide metoclopramide NN cord-022526-j9kg00qf 5746 36 for for IN cord-022526-j9kg00qf 5746 37 treatment treatment NN cord-022526-j9kg00qf 5746 38 of of IN cord-022526-j9kg00qf 5746 39 ileus ileus NN cord-022526-j9kg00qf 5746 40 in in IN cord-022526-j9kg00qf 5746 41 horses horse NNS cord-022526-j9kg00qf 5746 42 following follow VBG cord-022526-j9kg00qf 5746 43 small small JJ cord-022526-j9kg00qf 5746 44 intestinal intestinal JJ cord-022526-j9kg00qf 5746 45 surgery surgery NN cord-022526-j9kg00qf 5746 46 : : : cord-022526-j9kg00qf 5746 47 70 70 CD cord-022526-j9kg00qf 5746 48 cases case NNS cord-022526-j9kg00qf 5746 49 ( ( -LRB- cord-022526-j9kg00qf 5746 50 1989 1989 CD cord-022526-j9kg00qf 5746 51 - - SYM cord-022526-j9kg00qf 5746 52 1992 1992 CD cord-022526-j9kg00qf 5746 53 ) ) -RRB- cord-022526-j9kg00qf 5747 1 Role role NN cord-022526-j9kg00qf 5747 2 of of IN cord-022526-j9kg00qf 5747 3 the the DT cord-022526-j9kg00qf 5747 4 enteric enteric JJ cord-022526-j9kg00qf 5747 5 nervous nervous JJ cord-022526-j9kg00qf 5747 6 system system NN cord-022526-j9kg00qf 5747 7 in in IN cord-022526-j9kg00qf 5747 8 the the DT cord-022526-j9kg00qf 5747 9 fluid fluid NN cord-022526-j9kg00qf 5747 10 and and CC cord-022526-j9kg00qf 5747 11 electrolyte electrolyte JJ cord-022526-j9kg00qf 5747 12 secretion secretion NN cord-022526-j9kg00qf 5747 13 of of IN cord-022526-j9kg00qf 5747 14 rotavirus rotavirus JJ cord-022526-j9kg00qf 5747 15 diarrhea diarrhea NN cord-022526-j9kg00qf 5747 16 Prokinetic prokinetic JJ cord-022526-j9kg00qf 5747 17 effects effect NNS cord-022526-j9kg00qf 5747 18 of of IN cord-022526-j9kg00qf 5747 19 erythromycin erythromycin NN cord-022526-j9kg00qf 5747 20 on on IN cord-022526-j9kg00qf 5747 21 the the DT cord-022526-j9kg00qf 5747 22 ileum ileum NN cord-022526-j9kg00qf 5747 23 , , , cord-022526-j9kg00qf 5747 24 cecum cecum NN cord-022526-j9kg00qf 5747 25 , , , cord-022526-j9kg00qf 5747 26 and and CC cord-022526-j9kg00qf 5747 27 pelvic pelvic JJ cord-022526-j9kg00qf 5747 28 flexure flexure NN cord-022526-j9kg00qf 5747 29 of of IN cord-022526-j9kg00qf 5747 30 horses horse NNS cord-022526-j9kg00qf 5747 31 during during IN cord-022526-j9kg00qf 5747 32 the the DT cord-022526-j9kg00qf 5747 33 postoperative postoperative JJ cord-022526-j9kg00qf 5747 34 period period NN cord-022526-j9kg00qf 5747 35 Cecal Cecal NNP cord-022526-j9kg00qf 5747 36 impaction impaction NN cord-022526-j9kg00qf 5747 37 in in IN cord-022526-j9kg00qf 5747 38 the the DT cord-022526-j9kg00qf 5747 39 horse horse NN cord-022526-j9kg00qf 5747 40 Caecal Caecal NNP cord-022526-j9kg00qf 5747 41 disease disease NN cord-022526-j9kg00qf 5747 42 in in IN cord-022526-j9kg00qf 5747 43 equids equid NNS cord-022526-j9kg00qf 5747 44 Ileocolostomy Ileocolostomy NNP cord-022526-j9kg00qf 5747 45 : : : cord-022526-j9kg00qf 5747 46 a a DT cord-022526-j9kg00qf 5747 47 technique technique NN cord-022526-j9kg00qf 5747 48 for for IN cord-022526-j9kg00qf 5747 49 surgical surgical JJ cord-022526-j9kg00qf 5747 50 management management NN cord-022526-j9kg00qf 5747 51 of of IN cord-022526-j9kg00qf 5747 52 equine equine JJ cord-022526-j9kg00qf 5747 53 cecal cecal JJ cord-022526-j9kg00qf 5747 54 impaction impaction NN cord-022526-j9kg00qf 5747 55 Diseases disease NNS cord-022526-j9kg00qf 5747 56 and and CC cord-022526-j9kg00qf 5747 57 surgery surgery NN cord-022526-j9kg00qf 5747 58 of of IN cord-022526-j9kg00qf 5748 1 the the DT cord-022526-j9kg00qf 5748 2 cecum cecum NN cord-022526-j9kg00qf 5748 3 Treatment Treatment NNP cord-022526-j9kg00qf 5748 4 of of IN cord-022526-j9kg00qf 5748 5 impaction impaction NN cord-022526-j9kg00qf 5748 6 colics colic NNS cord-022526-j9kg00qf 5749 1 Large large JJ cord-022526-j9kg00qf 5749 2 colon colon NN cord-022526-j9kg00qf 5749 3 impaction impaction NN cord-022526-j9kg00qf 5749 4 in in IN cord-022526-j9kg00qf 5749 5 horses horse NNS cord-022526-j9kg00qf 5749 6 : : : cord-022526-j9kg00qf 5749 7 147 147 CD cord-022526-j9kg00qf 5749 8 cases case NNS cord-022526-j9kg00qf 5749 9 ( ( -LRB- cord-022526-j9kg00qf 5749 10 1985 1985 CD cord-022526-j9kg00qf 5749 11 - - SYM cord-022526-j9kg00qf 5749 12 1991 1991 CD cord-022526-j9kg00qf 5749 13 ) ) -RRB- cord-022526-j9kg00qf 5750 1 Effects effect NNS cord-022526-j9kg00qf 5750 2 of of IN cord-022526-j9kg00qf 5750 3 amitraz amitraz NN cord-022526-j9kg00qf 5750 4 , , , cord-022526-j9kg00qf 5750 5 several several JJ cord-022526-j9kg00qf 5750 6 opiate opiate NN cord-022526-j9kg00qf 5750 7 derivatives derivative NNS cord-022526-j9kg00qf 5750 8 and and CC cord-022526-j9kg00qf 5750 9 anticholinergic anticholinergic JJ cord-022526-j9kg00qf 5750 10 agents agent NNS cord-022526-j9kg00qf 5750 11 on on IN cord-022526-j9kg00qf 5750 12 intestinal intestinal JJ cord-022526-j9kg00qf 5750 13 transit transit NN cord-022526-j9kg00qf 5750 14 in in IN cord-022526-j9kg00qf 5750 15 ponies pony NNS cord-022526-j9kg00qf 5750 16 Experimental experimental JJ cord-022526-j9kg00qf 5750 17 studies study NNS cord-022526-j9kg00qf 5750 18 of of IN cord-022526-j9kg00qf 5750 19 druginduced druginduced JJ cord-022526-j9kg00qf 5750 20 impaction impaction NN cord-022526-j9kg00qf 5750 21 colic colic NN cord-022526-j9kg00qf 5750 22 in in IN cord-022526-j9kg00qf 5750 23 the the DT cord-022526-j9kg00qf 5750 24 horse horse NN cord-022526-j9kg00qf 5750 25 Retropulsion retropulsion NN cord-022526-j9kg00qf 5750 26 - - HYPH cord-022526-j9kg00qf 5750 27 propulsion propulsion NN cord-022526-j9kg00qf 5750 28 in in IN cord-022526-j9kg00qf 5750 29 equine equine JJ cord-022526-j9kg00qf 5750 30 large large JJ cord-022526-j9kg00qf 5750 31 colon colon NN cord-022526-j9kg00qf 5750 32 Clinical clinical JJ cord-022526-j9kg00qf 5750 33 and and CC cord-022526-j9kg00qf 5750 34 structural structural JJ cord-022526-j9kg00qf 5750 35 features feature NNS cord-022526-j9kg00qf 5750 36 of of IN cord-022526-j9kg00qf 5750 37 equine equine JJ cord-022526-j9kg00qf 5750 38 enteroliths enterolith NNS cord-022526-j9kg00qf 5750 39 Petrographic Petrographic NNP cord-022526-j9kg00qf 5750 40 and and CC cord-022526-j9kg00qf 5750 41 geochemic geochemic JJ cord-022526-j9kg00qf 5750 42 evaluation evaluation NN cord-022526-j9kg00qf 5750 43 of of IN cord-022526-j9kg00qf 5750 44 equine equine JJ cord-022526-j9kg00qf 5750 45 enteroliths enterolith NNS cord-022526-j9kg00qf 5750 46 Enteroliths Enteroliths NNPS cord-022526-j9kg00qf 5750 47 in in IN cord-022526-j9kg00qf 5750 48 horses horse NNS cord-022526-j9kg00qf 5750 49 Evaluation Evaluation NNP cord-022526-j9kg00qf 5750 50 of of IN cord-022526-j9kg00qf 5750 51 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5750 52 in in IN cord-022526-j9kg00qf 5750 53 equids equid NNS cord-022526-j9kg00qf 5750 54 : : : cord-022526-j9kg00qf 5750 55 900 900 CD cord-022526-j9kg00qf 5750 56 cases case NNS cord-022526-j9kg00qf 5750 57 Risk risk NN cord-022526-j9kg00qf 5750 58 factors factor NNS cord-022526-j9kg00qf 5750 59 for for IN cord-022526-j9kg00qf 5750 60 enterolithiasis enterolithiasis NN cord-022526-j9kg00qf 5750 61 among among IN cord-022526-j9kg00qf 5750 62 horses horse NNS cord-022526-j9kg00qf 5750 63 in in IN cord-022526-j9kg00qf 5750 64 Texas Texas NNP cord-022526-j9kg00qf 5750 65 Obstructive Obstructive NNP cord-022526-j9kg00qf 5750 66 enterolith enterolith NNP cord-022526-j9kg00qf 5750 67 in in IN cord-022526-j9kg00qf 5750 68 an an DT cord-022526-j9kg00qf 5750 69 11-month 11-month JJ cord-022526-j9kg00qf 5750 70 - - HYPH cord-022526-j9kg00qf 5750 71 old old JJ cord-022526-j9kg00qf 5750 72 miniature miniature JJ cord-022526-j9kg00qf 5750 73 horse horse NN cord-022526-j9kg00qf 5750 74 Surgical surgical JJ cord-022526-j9kg00qf 5750 75 treatment treatment NN cord-022526-j9kg00qf 5750 76 of of IN cord-022526-j9kg00qf 5750 77 sand sand NN cord-022526-j9kg00qf 5750 78 colic colic NN cord-022526-j9kg00qf 5750 79 in in IN cord-022526-j9kg00qf 5750 80 equids equid NNS cord-022526-j9kg00qf 5750 81 : : : cord-022526-j9kg00qf 5750 82 48 48 CD cord-022526-j9kg00qf 5750 83 cases case NNS cord-022526-j9kg00qf 5750 84 ( ( -LRB- cord-022526-j9kg00qf 5750 85 1978 1978 CD cord-022526-j9kg00qf 5750 86 - - SYM cord-022526-j9kg00qf 5750 87 1985 1985 CD cord-022526-j9kg00qf 5750 88 ) ) -RRB- cord-022526-j9kg00qf 5751 1 Surgical surgical JJ cord-022526-j9kg00qf 5751 2 treatment treatment NN cord-022526-j9kg00qf 5751 3 of of IN cord-022526-j9kg00qf 5751 4 sand sand NN cord-022526-j9kg00qf 5751 5 colic colic NN cord-022526-j9kg00qf 5751 6 : : : cord-022526-j9kg00qf 5751 7 results result NNS cord-022526-j9kg00qf 5751 8 in in IN cord-022526-j9kg00qf 5751 9 40 40 CD cord-022526-j9kg00qf 5751 10 horses horse NNS cord-022526-j9kg00qf 5751 11 Diarrhea diarrhea VBP cord-022526-j9kg00qf 5751 12 associated associate VBN cord-022526-j9kg00qf 5751 13 with with IN cord-022526-j9kg00qf 5751 14 sand sand NN cord-022526-j9kg00qf 5751 15 in in IN cord-022526-j9kg00qf 5751 16 the the DT cord-022526-j9kg00qf 5751 17 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5751 18 tract tract NN cord-022526-j9kg00qf 5751 19 of of IN cord-022526-j9kg00qf 5751 20 horses horse NNS cord-022526-j9kg00qf 5751 21 Abdominal abdominal JJ cord-022526-j9kg00qf 5751 22 auscultation auscultation NN cord-022526-j9kg00qf 5751 23 in in IN cord-022526-j9kg00qf 5751 24 the the DT cord-022526-j9kg00qf 5751 25 detection detection NN cord-022526-j9kg00qf 5751 26 of of IN cord-022526-j9kg00qf 5751 27 experimentally experimentally RB cord-022526-j9kg00qf 5751 28 induced induce VBN cord-022526-j9kg00qf 5751 29 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5751 30 sand sand NN cord-022526-j9kg00qf 5751 31 accumulation accumulation NN cord-022526-j9kg00qf 5751 32 Failure failure NN cord-022526-j9kg00qf 5751 33 of of IN cord-022526-j9kg00qf 5751 34 psyllium psyllium NN cord-022526-j9kg00qf 5751 35 mucilloid mucilloid NN cord-022526-j9kg00qf 5751 36 to to TO cord-022526-j9kg00qf 5751 37 hasten hasten VB cord-022526-j9kg00qf 5751 38 evaluation evaluation NN cord-022526-j9kg00qf 5751 39 of of IN cord-022526-j9kg00qf 5751 40 sand sand NN cord-022526-j9kg00qf 5751 41 from from IN cord-022526-j9kg00qf 5751 42 the the DT cord-022526-j9kg00qf 5751 43 equine equine JJ cord-022526-j9kg00qf 5751 44 large large JJ cord-022526-j9kg00qf 5751 45 intestine intestine NN cord-022526-j9kg00qf 5752 1 Nonstrangulated nonstrangulated JJ cord-022526-j9kg00qf 5752 2 colonic colonic JJ cord-022526-j9kg00qf 5752 3 displacement displacement NN cord-022526-j9kg00qf 5752 4 in in IN cord-022526-j9kg00qf 5752 5 horses horse NNS cord-022526-j9kg00qf 5752 6 Functions function NNS cord-022526-j9kg00qf 5752 7 of of IN cord-022526-j9kg00qf 5752 8 the the DT cord-022526-j9kg00qf 5752 9 equine equine JJ cord-022526-j9kg00qf 5752 10 large large JJ cord-022526-j9kg00qf 5752 11 intestine intestine NN cord-022526-j9kg00qf 5752 12 and and CC cord-022526-j9kg00qf 5752 13 their -PRON- PRP$ cord-022526-j9kg00qf 5752 14 interrelationship interrelationship NN cord-022526-j9kg00qf 5752 15 in in IN cord-022526-j9kg00qf 5752 16 disease disease NN cord-022526-j9kg00qf 5752 17 Comparisons comparison NNS cord-022526-j9kg00qf 5752 18 of of IN cord-022526-j9kg00qf 5752 19 age age NN cord-022526-j9kg00qf 5752 20 , , , cord-022526-j9kg00qf 5752 21 breed breed NN cord-022526-j9kg00qf 5752 22 , , , cord-022526-j9kg00qf 5752 23 history history NN cord-022526-j9kg00qf 5752 24 and and CC cord-022526-j9kg00qf 5752 25 management management NN cord-022526-j9kg00qf 5752 26 in in IN cord-022526-j9kg00qf 5752 27 229 229 CD cord-022526-j9kg00qf 5752 28 horses horse NNS cord-022526-j9kg00qf 5752 29 with with IN cord-022526-j9kg00qf 5752 30 colic colic NN cord-022526-j9kg00qf 5752 31 Motor Motor NNP cord-022526-j9kg00qf 5752 32 functions function NNS cord-022526-j9kg00qf 5752 33 of of IN cord-022526-j9kg00qf 5752 34 the the DT cord-022526-j9kg00qf 5752 35 intestine intestine NN cord-022526-j9kg00qf 5753 1 The the DT cord-022526-j9kg00qf 5753 2 effect effect NN cord-022526-j9kg00qf 5753 3 of of IN cord-022526-j9kg00qf 5753 4 Strongylus Strongylus NNP cord-022526-j9kg00qf 5753 5 vulgaris vulgaris NN cord-022526-j9kg00qf 5753 6 larvae larva NNS cord-022526-j9kg00qf 5753 7 on on IN cord-022526-j9kg00qf 5753 8 equine equine JJ cord-022526-j9kg00qf 5753 9 intestinal intestinal JJ cord-022526-j9kg00qf 5753 10 myoelectrical myoelectrical JJ cord-022526-j9kg00qf 5753 11 activity activity NN cord-022526-j9kg00qf 5753 12 Displacement displacement NN cord-022526-j9kg00qf 5753 13 of of IN cord-022526-j9kg00qf 5753 14 the the DT cord-022526-j9kg00qf 5753 15 large large JJ cord-022526-j9kg00qf 5753 16 colon colon NN cord-022526-j9kg00qf 5753 17 Reversal reversal NN cord-022526-j9kg00qf 5753 18 of of IN cord-022526-j9kg00qf 5753 19 colonic colonic JJ cord-022526-j9kg00qf 5753 20 net net JJ cord-022526-j9kg00qf 5753 21 absorption absorption NN cord-022526-j9kg00qf 5753 22 to to IN cord-022526-j9kg00qf 5753 23 net net JJ cord-022526-j9kg00qf 5753 24 secretion secretion NN cord-022526-j9kg00qf 5753 25 with with IN cord-022526-j9kg00qf 5753 26 increased increase VBN cord-022526-j9kg00qf 5753 27 intraluminal intraluminal JJ cord-022526-j9kg00qf 5753 28 pressure pressure NN cord-022526-j9kg00qf 5753 29 Use use NN cord-022526-j9kg00qf 5753 30 of of IN cord-022526-j9kg00qf 5753 31 ultrasound ultrasound NN cord-022526-j9kg00qf 5753 32 in in IN cord-022526-j9kg00qf 5753 33 horses horse NNS cord-022526-j9kg00qf 5753 34 for for IN cord-022526-j9kg00qf 5753 35 diagnosis diagnosis NN cord-022526-j9kg00qf 5753 36 of of IN cord-022526-j9kg00qf 5753 37 left left JJ cord-022526-j9kg00qf 5753 38 dorsal dorsal JJ cord-022526-j9kg00qf 5753 39 displacement displacement NN cord-022526-j9kg00qf 5753 40 of of IN cord-022526-j9kg00qf 5753 41 the the DT cord-022526-j9kg00qf 5753 42 large large JJ cord-022526-j9kg00qf 5753 43 colon colon NN cord-022526-j9kg00qf 5753 44 and and CC cord-022526-j9kg00qf 5753 45 monitoring monitor VBG cord-022526-j9kg00qf 5753 46 its -PRON- PRP$ cord-022526-j9kg00qf 5753 47 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5753 48 correction correction NN cord-022526-j9kg00qf 5753 49 Renosplenic Renosplenic NNP cord-022526-j9kg00qf 5753 50 entrapment entrapment NN cord-022526-j9kg00qf 5753 51 of of IN cord-022526-j9kg00qf 5753 52 the the DT cord-022526-j9kg00qf 5753 53 large large JJ cord-022526-j9kg00qf 5753 54 colon colon NN cord-022526-j9kg00qf 5753 55 in in IN cord-022526-j9kg00qf 5753 56 horses horse NNS cord-022526-j9kg00qf 5753 57 : : : cord-022526-j9kg00qf 5753 58 33 33 CD cord-022526-j9kg00qf 5753 59 cases case NNS cord-022526-j9kg00qf 5753 60 Renosplenic Renosplenic NNP cord-022526-j9kg00qf 5753 61 entrapment entrapment NN cord-022526-j9kg00qf 5753 62 of of IN cord-022526-j9kg00qf 5753 63 the the DT cord-022526-j9kg00qf 5753 64 large large JJ cord-022526-j9kg00qf 5753 65 colon colon NN cord-022526-j9kg00qf 5753 66 in in IN cord-022526-j9kg00qf 5753 67 horses horse NNS cord-022526-j9kg00qf 5753 68 : : : cord-022526-j9kg00qf 5754 1 57 57 CD cord-022526-j9kg00qf 5754 2 cases case NNS cord-022526-j9kg00qf 5755 1 Further further JJ cord-022526-j9kg00qf 5755 2 experiences experience NNS cord-022526-j9kg00qf 5755 3 with with IN cord-022526-j9kg00qf 5755 4 non non JJ cord-022526-j9kg00qf 5755 5 - - JJ cord-022526-j9kg00qf 5755 6 surgical surgical JJ cord-022526-j9kg00qf 5755 7 correction correction NN cord-022526-j9kg00qf 5755 8 of of IN cord-022526-j9kg00qf 5755 9 nephrosplenic nephrosplenic JJ cord-022526-j9kg00qf 5755 10 entrapment entrapment NN cord-022526-j9kg00qf 5755 11 of of IN cord-022526-j9kg00qf 5755 12 the the DT cord-022526-j9kg00qf 5755 13 left left JJ cord-022526-j9kg00qf 5755 14 colon colon NN cord-022526-j9kg00qf 5755 15 in in IN cord-022526-j9kg00qf 5755 16 the the DT cord-022526-j9kg00qf 5755 17 horse horse NN cord-022526-j9kg00qf 5755 18 Effect effect NN cord-022526-j9kg00qf 5755 19 of of IN cord-022526-j9kg00qf 5755 20 phenylephrine phenylephrine NN cord-022526-j9kg00qf 5755 21 on on IN cord-022526-j9kg00qf 5755 22 hemodynamics hemodynamic NNS cord-022526-j9kg00qf 5755 23 and and CC cord-022526-j9kg00qf 5755 24 splenic splenic JJ cord-022526-j9kg00qf 5755 25 dimensions dimension NNS cord-022526-j9kg00qf 5755 26 in in IN cord-022526-j9kg00qf 5755 27 horses horse NNS cord-022526-j9kg00qf 5755 28 Displacement displacement NN cord-022526-j9kg00qf 5755 29 of of IN cord-022526-j9kg00qf 5755 30 the the DT cord-022526-j9kg00qf 5755 31 large large JJ cord-022526-j9kg00qf 5755 32 colon colon NN cord-022526-j9kg00qf 5755 33 associated associate VBN cord-022526-j9kg00qf 5755 34 with with IN cord-022526-j9kg00qf 5755 35 nonsurgical nonsurgical JJ cord-022526-j9kg00qf 5755 36 correction correction NN cord-022526-j9kg00qf 5755 37 of of IN cord-022526-j9kg00qf 5755 38 large large JJ cord-022526-j9kg00qf 5755 39 - - HYPH cord-022526-j9kg00qf 5755 40 colon colon NN cord-022526-j9kg00qf 5755 41 entrapment entrapment NN cord-022526-j9kg00qf 5755 42 in in IN cord-022526-j9kg00qf 5755 43 the the DT cord-022526-j9kg00qf 5755 44 renosplenic renosplenic JJ cord-022526-j9kg00qf 5755 45 space space NN cord-022526-j9kg00qf 5755 46 in in IN cord-022526-j9kg00qf 5755 47 a a DT cord-022526-j9kg00qf 5755 48 mare mare JJ cord-022526-j9kg00qf 5755 49 Foreign foreign JJ cord-022526-j9kg00qf 5755 50 body body NN cord-022526-j9kg00qf 5755 51 obstruction obstruction NN cord-022526-j9kg00qf 5755 52 of of IN cord-022526-j9kg00qf 5755 53 the the DT cord-022526-j9kg00qf 5755 54 small small JJ cord-022526-j9kg00qf 5755 55 colon colon NN cord-022526-j9kg00qf 5755 56 in in IN cord-022526-j9kg00qf 5755 57 six six CD cord-022526-j9kg00qf 5755 58 horses horse NNS cord-022526-j9kg00qf 5755 59 Fecalith Fecalith NNP cord-022526-j9kg00qf 5755 60 impaction impaction NN cord-022526-j9kg00qf 5755 61 in in IN cord-022526-j9kg00qf 5755 62 four four CD cord-022526-j9kg00qf 5755 63 miniature miniature JJ cord-022526-j9kg00qf 5755 64 foals foal NNS cord-022526-j9kg00qf 5755 65 Obstruction obstruction NN cord-022526-j9kg00qf 5755 66 of of IN cord-022526-j9kg00qf 5755 67 the the DT cord-022526-j9kg00qf 5755 68 small small JJ cord-022526-j9kg00qf 5755 69 colon colon NN cord-022526-j9kg00qf 5755 70 by by IN cord-022526-j9kg00qf 5755 71 intramural intramural JJ cord-022526-j9kg00qf 5755 72 haematoma haematoma NN cord-022526-j9kg00qf 5755 73 in in IN cord-022526-j9kg00qf 5755 74 three three CD cord-022526-j9kg00qf 5755 75 horses horse NNS cord-022526-j9kg00qf 5755 76 Submucosal Submucosal NNP cord-022526-j9kg00qf 5755 77 haematoma haematoma NN cord-022526-j9kg00qf 5755 78 as as IN cord-022526-j9kg00qf 5755 79 a a DT cord-022526-j9kg00qf 5755 80 cause cause NN cord-022526-j9kg00qf 5755 81 of of IN cord-022526-j9kg00qf 5755 82 obstruction obstruction NN cord-022526-j9kg00qf 5755 83 of of IN cord-022526-j9kg00qf 5755 84 the the DT cord-022526-j9kg00qf 5755 85 small small JJ cord-022526-j9kg00qf 5755 86 colon colon NN cord-022526-j9kg00qf 5755 87 in in IN cord-022526-j9kg00qf 5755 88 the the DT cord-022526-j9kg00qf 5755 89 horse horse NN cord-022526-j9kg00qf 5755 90 : : : cord-022526-j9kg00qf 5755 91 a a DT cord-022526-j9kg00qf 5755 92 review review NN cord-022526-j9kg00qf 5755 93 of of IN cord-022526-j9kg00qf 5755 94 four four CD cord-022526-j9kg00qf 5755 95 cases case NNS cord-022526-j9kg00qf 5755 96 Inflammatory inflammatory JJ cord-022526-j9kg00qf 5755 97 bowel bowel NN cord-022526-j9kg00qf 5755 98 disease disease NN cord-022526-j9kg00qf 5755 99 in in IN cord-022526-j9kg00qf 5755 100 horses horse NNS cord-022526-j9kg00qf 5755 101 : : : cord-022526-j9kg00qf 5755 102 11 11 CD cord-022526-j9kg00qf 5755 103 cases case NNS cord-022526-j9kg00qf 5756 1 Intestinal intestinal JJ cord-022526-j9kg00qf 5756 2 atresia atresia NN cord-022526-j9kg00qf 5756 3 in in IN cord-022526-j9kg00qf 5756 4 horses horse NNS cord-022526-j9kg00qf 5756 5 Clinical clinical JJ cord-022526-j9kg00qf 5756 6 survey survey NN cord-022526-j9kg00qf 5756 7 of of IN cord-022526-j9kg00qf 5756 8 tumours tumour NNS cord-022526-j9kg00qf 5756 9 and and CC cord-022526-j9kg00qf 5756 10 tumourlike tumourlike JJ cord-022526-j9kg00qf 5756 11 lesions lesion NNS cord-022526-j9kg00qf 5756 12 in in IN cord-022526-j9kg00qf 5756 13 horses horse NNS cord-022526-j9kg00qf 5756 14 in in IN cord-022526-j9kg00qf 5756 15 south south NNP cord-022526-j9kg00qf 5756 16 east east NNP cord-022526-j9kg00qf 5756 17 Queensland Queensland NNP cord-022526-j9kg00qf 5756 18 Abdominal abdominal JJ cord-022526-j9kg00qf 5756 19 neoplasia neoplasia NN cord-022526-j9kg00qf 5756 20 ( ( -LRB- cord-022526-j9kg00qf 5756 21 excluding exclude VBG cord-022526-j9kg00qf 5756 22 urogenital urogenital JJ cord-022526-j9kg00qf 5756 23 tract tract NN cord-022526-j9kg00qf 5756 24 ) ) -RRB- cord-022526-j9kg00qf 5757 1 Clinical clinical JJ cord-022526-j9kg00qf 5757 2 manifestation manifestation NN cord-022526-j9kg00qf 5757 3 of of IN cord-022526-j9kg00qf 5757 4 squamous squamous JJ cord-022526-j9kg00qf 5757 5 cell cell NN cord-022526-j9kg00qf 5757 6 carcinoma carcinoma NN cord-022526-j9kg00qf 5757 7 in in IN cord-022526-j9kg00qf 5757 8 horses horse NNS cord-022526-j9kg00qf 5758 1 Lymphoma Lymphoma NNP cord-022526-j9kg00qf 5758 2 ( ( -LRB- cord-022526-j9kg00qf 5758 3 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5758 4 ) ) -RRB- cord-022526-j9kg00qf 5758 5 in in IN cord-022526-j9kg00qf 5758 6 horses horse NNS cord-022526-j9kg00qf 5758 7 Oral oral JJ cord-022526-j9kg00qf 5758 8 and and CC cord-022526-j9kg00qf 5758 9 dental dental JJ cord-022526-j9kg00qf 5758 10 tumors tumor NNS cord-022526-j9kg00qf 5758 11 in in IN cord-022526-j9kg00qf 5758 12 equine equine NN cord-022526-j9kg00qf 5758 13 denistry denistry NN cord-022526-j9kg00qf 5758 14 T T NNP cord-022526-j9kg00qf 5758 15 cell cell NN cord-022526-j9kg00qf 5758 16 - - HYPH cord-022526-j9kg00qf 5758 17 rich rich JJ cord-022526-j9kg00qf 5758 18 B b NN cord-022526-j9kg00qf 5758 19 cell cell NN cord-022526-j9kg00qf 5758 20 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 5758 21 in in IN cord-022526-j9kg00qf 5758 22 the the DT cord-022526-j9kg00qf 5758 23 tongue tongue NN cord-022526-j9kg00qf 5758 24 of of IN cord-022526-j9kg00qf 5758 25 a a DT cord-022526-j9kg00qf 5758 26 horse horse NN cord-022526-j9kg00qf 5758 27 Multiple multiple JJ cord-022526-j9kg00qf 5758 28 myeloma myeloma NN cord-022526-j9kg00qf 5758 29 in in IN cord-022526-j9kg00qf 5758 30 a a DT cord-022526-j9kg00qf 5758 31 horse horse NN cord-022526-j9kg00qf 5758 32 Rhabdomyosarcoma Rhabdomyosarcoma NNP cord-022526-j9kg00qf 5758 33 of of IN cord-022526-j9kg00qf 5758 34 the the DT cord-022526-j9kg00qf 5758 35 tongue tongue NN cord-022526-j9kg00qf 5758 36 in in IN cord-022526-j9kg00qf 5758 37 a a DT cord-022526-j9kg00qf 5758 38 horse horse NN cord-022526-j9kg00qf 5758 39 Paraneoplastic paraneoplastic JJ cord-022526-j9kg00qf 5758 40 bullous bullous JJ cord-022526-j9kg00qf 5758 41 stomatitis stomatitis NN cord-022526-j9kg00qf 5758 42 in in IN cord-022526-j9kg00qf 5758 43 a a DT cord-022526-j9kg00qf 5758 44 horse horse NN cord-022526-j9kg00qf 5758 45 Gastric gastric JJ cord-022526-j9kg00qf 5758 46 squamous squamous JJ cord-022526-j9kg00qf 5758 47 cell cell NN cord-022526-j9kg00qf 5758 48 carcinoma carcinoma NN cord-022526-j9kg00qf 5758 49 in in IN cord-022526-j9kg00qf 5758 50 three three CD cord-022526-j9kg00qf 5758 51 horses horse NNS cord-022526-j9kg00qf 5758 52 Use use VBP cord-022526-j9kg00qf 5758 53 of of IN cord-022526-j9kg00qf 5758 54 esophagoscopy esophagoscopy NNP cord-022526-j9kg00qf 5758 55 in in IN cord-022526-j9kg00qf 5758 56 the the DT cord-022526-j9kg00qf 5758 57 diagnosis diagnosis NN cord-022526-j9kg00qf 5758 58 of of IN cord-022526-j9kg00qf 5758 59 esophageal esophageal JJ cord-022526-j9kg00qf 5758 60 squamous squamous JJ cord-022526-j9kg00qf 5758 61 cell cell NN cord-022526-j9kg00qf 5758 62 carcinoma carcinoma NN cord-022526-j9kg00qf 5758 63 in in IN cord-022526-j9kg00qf 5758 64 a a DT cord-022526-j9kg00qf 5758 65 horse horse NN cord-022526-j9kg00qf 5758 66 Gastric gastric JJ cord-022526-j9kg00qf 5758 67 hyperplastic hyperplastic JJ cord-022526-j9kg00qf 5758 68 polyp polyp NN cord-022526-j9kg00qf 5758 69 in in IN cord-022526-j9kg00qf 5758 70 a a DT cord-022526-j9kg00qf 5758 71 horse horse NN cord-022526-j9kg00qf 5758 72 Gastric gastric JJ cord-022526-j9kg00qf 5758 73 leiomyosarcoma leiomyosarcoma NN cord-022526-j9kg00qf 5758 74 in in IN cord-022526-j9kg00qf 5758 75 a a DT cord-022526-j9kg00qf 5758 76 horse horse NN cord-022526-j9kg00qf 5758 77 Multisystemic Multisystemic NNP cord-022526-j9kg00qf 5758 78 , , , cord-022526-j9kg00qf 5758 79 eosinophilic eosinophilic JJ cord-022526-j9kg00qf 5758 80 , , , cord-022526-j9kg00qf 5758 81 epitheliotropic epitheliotropic JJ cord-022526-j9kg00qf 5758 82 disease disease NN cord-022526-j9kg00qf 5758 83 with with IN cord-022526-j9kg00qf 5758 84 intestinal intestinal JJ cord-022526-j9kg00qf 5758 85 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 5758 86 in in IN cord-022526-j9kg00qf 5758 87 a a DT cord-022526-j9kg00qf 5758 88 horse horse NN cord-022526-j9kg00qf 5759 1 An an DT cord-022526-j9kg00qf 5759 2 immunohistochemical immunohistochemical JJ cord-022526-j9kg00qf 5759 3 study study NN cord-022526-j9kg00qf 5759 4 of of IN cord-022526-j9kg00qf 5759 5 equine equine JJ cord-022526-j9kg00qf 5759 6 B b NN cord-022526-j9kg00qf 5759 7 - - HYPH cord-022526-j9kg00qf 5759 8 cell cell NN cord-022526-j9kg00qf 5759 9 lymphoma lymphoma NN cord-022526-j9kg00qf 5759 10 Squamous squamous JJ cord-022526-j9kg00qf 5759 11 cell cell NN cord-022526-j9kg00qf 5759 12 carcinoma carcinoma NN cord-022526-j9kg00qf 5759 13 of of IN cord-022526-j9kg00qf 5759 14 the the DT cord-022526-j9kg00qf 5759 15 equine equine JJ cord-022526-j9kg00qf 5759 16 stomach stomach NN cord-022526-j9kg00qf 5759 17 : : : cord-022526-j9kg00qf 5759 18 a a DT cord-022526-j9kg00qf 5759 19 report report NN cord-022526-j9kg00qf 5759 20 of of IN cord-022526-j9kg00qf 5759 21 five five CD cord-022526-j9kg00qf 5759 22 cases case NNS cord-022526-j9kg00qf 5759 23 Six six CD cord-022526-j9kg00qf 5759 24 cases case NNS cord-022526-j9kg00qf 5759 25 of of IN cord-022526-j9kg00qf 5759 26 squamous squamous JJ cord-022526-j9kg00qf 5759 27 cell cell NN cord-022526-j9kg00qf 5759 28 carcinoma carcinoma NN cord-022526-j9kg00qf 5759 29 of of IN cord-022526-j9kg00qf 5759 30 the the DT cord-022526-j9kg00qf 5759 31 stomach stomach NN cord-022526-j9kg00qf 5759 32 of of IN cord-022526-j9kg00qf 5759 33 the the DT cord-022526-j9kg00qf 5759 34 horse horse NN cord-022526-j9kg00qf 5759 35 Small small JJ cord-022526-j9kg00qf 5759 36 intestinal intestinal JJ cord-022526-j9kg00qf 5759 37 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5759 38 in in IN cord-022526-j9kg00qf 5759 39 a a DT cord-022526-j9kg00qf 5759 40 horse horse NN cord-022526-j9kg00qf 5759 41 Ganglioneuroma Ganglioneuroma NNP cord-022526-j9kg00qf 5759 42 as as IN cord-022526-j9kg00qf 5759 43 a a DT cord-022526-j9kg00qf 5759 44 cause cause NN cord-022526-j9kg00qf 5759 45 of of IN cord-022526-j9kg00qf 5759 46 small small JJ cord-022526-j9kg00qf 5759 47 intestinal intestinal JJ cord-022526-j9kg00qf 5759 48 obstruction obstruction NN cord-022526-j9kg00qf 5759 49 in in IN cord-022526-j9kg00qf 5759 50 the the DT cord-022526-j9kg00qf 5759 51 horse horse NN cord-022526-j9kg00qf 5759 52 : : : cord-022526-j9kg00qf 5759 53 a a DT cord-022526-j9kg00qf 5759 54 case case NN cord-022526-j9kg00qf 5759 55 report report NN cord-022526-j9kg00qf 5759 56 Intestinal intestinal JJ cord-022526-j9kg00qf 5759 57 carcinoid carcinoid NN cord-022526-j9kg00qf 5759 58 in in IN cord-022526-j9kg00qf 5759 59 a a DT cord-022526-j9kg00qf 5759 60 mare mare NN cord-022526-j9kg00qf 5759 61 : : : cord-022526-j9kg00qf 5760 1 an an DT cord-022526-j9kg00qf 5760 2 etiologic etiologic JJ cord-022526-j9kg00qf 5760 3 consideration consideration NN cord-022526-j9kg00qf 5760 4 for for IN cord-022526-j9kg00qf 5760 5 chronic chronic JJ cord-022526-j9kg00qf 5760 6 colic colic NN cord-022526-j9kg00qf 5760 7 in in IN cord-022526-j9kg00qf 5760 8 horses horse NNS cord-022526-j9kg00qf 5760 9 Leiomyoma Leiomyoma NNP cord-022526-j9kg00qf 5760 10 of of IN cord-022526-j9kg00qf 5760 11 the the DT cord-022526-j9kg00qf 5760 12 small small JJ cord-022526-j9kg00qf 5760 13 intestine intestine NN cord-022526-j9kg00qf 5760 14 in in IN cord-022526-j9kg00qf 5760 15 a a DT cord-022526-j9kg00qf 5760 16 horse horse NN cord-022526-j9kg00qf 5760 17 Jejunal Jejunal NNP cord-022526-j9kg00qf 5760 18 intussusception intussusception NN cord-022526-j9kg00qf 5760 19 associated associate VBN cord-022526-j9kg00qf 5760 20 with with IN cord-022526-j9kg00qf 5760 21 leiomyoma leiomyoma NNP cord-022526-j9kg00qf 5760 22 in in IN cord-022526-j9kg00qf 5760 23 an an DT cord-022526-j9kg00qf 5760 24 aged aged JJ cord-022526-j9kg00qf 5760 25 horse horse NN cord-022526-j9kg00qf 5760 26 Duodenal duodenal NN cord-022526-j9kg00qf 5760 27 leiomyoma leiomyoma NNS cord-022526-j9kg00qf 5760 28 associated associate VBN cord-022526-j9kg00qf 5760 29 with with IN cord-022526-j9kg00qf 5760 30 colic colic NN cord-022526-j9kg00qf 5760 31 in in IN cord-022526-j9kg00qf 5760 32 a a DT cord-022526-j9kg00qf 5760 33 two two CD cord-022526-j9kg00qf 5760 34 - - HYPH cord-022526-j9kg00qf 5760 35 year year NN cord-022526-j9kg00qf 5760 36 - - HYPH cord-022526-j9kg00qf 5760 37 old old JJ cord-022526-j9kg00qf 5760 38 horse horse NN cord-022526-j9kg00qf 5760 39 Leiomyosarcoma Leiomyosarcoma NNP cord-022526-j9kg00qf 5760 40 of of IN cord-022526-j9kg00qf 5760 41 the the DT cord-022526-j9kg00qf 5760 42 duodenum duodenum NN cord-022526-j9kg00qf 5760 43 in in IN cord-022526-j9kg00qf 5760 44 two two CD cord-022526-j9kg00qf 5760 45 horses horse NNS cord-022526-j9kg00qf 5761 1 Pedunculated pedunculate VBN cord-022526-j9kg00qf 5761 2 lipomas lipoma NNS cord-022526-j9kg00qf 5761 3 as as IN cord-022526-j9kg00qf 5761 4 a a DT cord-022526-j9kg00qf 5761 5 cause cause NN cord-022526-j9kg00qf 5761 6 of of IN cord-022526-j9kg00qf 5761 7 intestinal intestinal JJ cord-022526-j9kg00qf 5761 8 obstruction obstruction NN cord-022526-j9kg00qf 5761 9 in in IN cord-022526-j9kg00qf 5761 10 horses horse NNS cord-022526-j9kg00qf 5761 11 : : : cord-022526-j9kg00qf 5761 12 17 17 CD cord-022526-j9kg00qf 5761 13 cases case NNS cord-022526-j9kg00qf 5761 14 ( ( -LRB- cord-022526-j9kg00qf 5761 15 1983 1983 CD cord-022526-j9kg00qf 5761 16 - - SYM cord-022526-j9kg00qf 5761 17 1990 1990 CD cord-022526-j9kg00qf 5761 18 ) ) -RRB- cord-022526-j9kg00qf 5762 1 Clinical clinical JJ cord-022526-j9kg00qf 5762 2 aspects aspect NNS cord-022526-j9kg00qf 5762 3 of of IN cord-022526-j9kg00qf 5762 4 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5762 5 in in IN cord-022526-j9kg00qf 5762 6 the the DT cord-022526-j9kg00qf 5762 7 horse horse NN cord-022526-j9kg00qf 5762 8 : : : cord-022526-j9kg00qf 5762 9 a a DT cord-022526-j9kg00qf 5762 10 clinical clinical JJ cord-022526-j9kg00qf 5762 11 report report NN cord-022526-j9kg00qf 5762 12 of of IN cord-022526-j9kg00qf 5762 13 16 16 CD cord-022526-j9kg00qf 5762 14 cases case NNS cord-022526-j9kg00qf 5762 15 Multiple multiple JJ cord-022526-j9kg00qf 5762 16 peripheral peripheral JJ cord-022526-j9kg00qf 5762 17 nerve nerve NN cord-022526-j9kg00qf 5762 18 sheath sheath NN cord-022526-j9kg00qf 5762 19 tumors tumor NNS cord-022526-j9kg00qf 5762 20 in in IN cord-022526-j9kg00qf 5762 21 the the DT cord-022526-j9kg00qf 5762 22 small small JJ cord-022526-j9kg00qf 5762 23 intestine intestine NN cord-022526-j9kg00qf 5762 24 of of IN cord-022526-j9kg00qf 5762 25 a a DT cord-022526-j9kg00qf 5762 26 horse horse NN cord-022526-j9kg00qf 5762 27 Equine equine NN cord-022526-j9kg00qf 5762 28 adenocarcinomas adenocarcinomas NN cord-022526-j9kg00qf 5762 29 of of IN cord-022526-j9kg00qf 5762 30 the the DT cord-022526-j9kg00qf 5762 31 large large JJ cord-022526-j9kg00qf 5762 32 intestine intestine NN cord-022526-j9kg00qf 5762 33 with with IN cord-022526-j9kg00qf 5762 34 osseous osseous JJ cord-022526-j9kg00qf 5762 35 metaplasia metaplasia NN cord-022526-j9kg00qf 5762 36 Intestinal intestinal JJ cord-022526-j9kg00qf 5762 37 myxosarcoma myxosarcoma NN cord-022526-j9kg00qf 5762 38 in in IN cord-022526-j9kg00qf 5762 39 a a DT cord-022526-j9kg00qf 5762 40 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5762 41 mare mare NN cord-022526-j9kg00qf 5762 42 Gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5762 43 stromal stromal JJ cord-022526-j9kg00qf 5762 44 tumors tumor NNS cord-022526-j9kg00qf 5762 45 of of IN cord-022526-j9kg00qf 5762 46 the the DT cord-022526-j9kg00qf 5762 47 equine equine JJ cord-022526-j9kg00qf 5762 48 cecum cecum NN cord-022526-j9kg00qf 5762 49 Colonic colonic JJ cord-022526-j9kg00qf 5762 50 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5762 51 with with IN cord-022526-j9kg00qf 5762 52 osseous osseous JJ cord-022526-j9kg00qf 5762 53 metaplasia metaplasia NN cord-022526-j9kg00qf 5762 54 in in IN cord-022526-j9kg00qf 5762 55 a a DT cord-022526-j9kg00qf 5762 56 horse horse NN cord-022526-j9kg00qf 5762 57 Intestinal intestinal JJ cord-022526-j9kg00qf 5762 58 adenocarcinoma adenocarcinoma NN cord-022526-j9kg00qf 5762 59 causing cause VBG cord-022526-j9kg00qf 5762 60 recurrent recurrent JJ cord-022526-j9kg00qf 5762 61 colic colic NN cord-022526-j9kg00qf 5762 62 in in IN cord-022526-j9kg00qf 5762 63 the the DT cord-022526-j9kg00qf 5762 64 horse horse NN cord-022526-j9kg00qf 5762 65 Equine equine JJ cord-022526-j9kg00qf 5762 66 colonic colonic JJ cord-022526-j9kg00qf 5762 67 lipomatosis lipomatosis NN cord-022526-j9kg00qf 5762 68 Large large JJ cord-022526-j9kg00qf 5762 69 colon colon NN cord-022526-j9kg00qf 5762 70 resection resection NN cord-022526-j9kg00qf 5762 71 for for IN cord-022526-j9kg00qf 5762 72 treatment treatment NN cord-022526-j9kg00qf 5762 73 of of IN cord-022526-j9kg00qf 5762 74 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5762 75 in in IN cord-022526-j9kg00qf 5762 76 two two CD cord-022526-j9kg00qf 5762 77 horses horse NNS cord-022526-j9kg00qf 5762 78 Colic colic VBP cord-022526-j9kg00qf 5762 79 in in IN cord-022526-j9kg00qf 5762 80 a a DT cord-022526-j9kg00qf 5762 81 mare mare NN cord-022526-j9kg00qf 5762 82 caused cause VBN cord-022526-j9kg00qf 5762 83 by by IN cord-022526-j9kg00qf 5762 84 a a DT cord-022526-j9kg00qf 5762 85 colonic colonic JJ cord-022526-j9kg00qf 5762 86 neurofibroma neurofibroma NNP cord-022526-j9kg00qf 5762 87 Small small JJ cord-022526-j9kg00qf 5762 88 colon colon NN cord-022526-j9kg00qf 5762 89 intussusception intussusception NN cord-022526-j9kg00qf 5762 90 associated associate VBN cord-022526-j9kg00qf 5762 91 with with IN cord-022526-j9kg00qf 5762 92 an an DT cord-022526-j9kg00qf 5762 93 intralumenal intralumenal JJ cord-022526-j9kg00qf 5762 94 leiomyoma leiomyoma NN cord-022526-j9kg00qf 5762 95 in in IN cord-022526-j9kg00qf 5762 96 a a DT cord-022526-j9kg00qf 5762 97 pony pony NN cord-022526-j9kg00qf 5762 98 Leiomyoma Leiomyoma NNP cord-022526-j9kg00qf 5762 99 of of IN cord-022526-j9kg00qf 5762 100 the the DT cord-022526-j9kg00qf 5762 101 small small JJ cord-022526-j9kg00qf 5762 102 colon colon NN cord-022526-j9kg00qf 5762 103 in in IN cord-022526-j9kg00qf 5762 104 a a DT cord-022526-j9kg00qf 5762 105 horse horse NN cord-022526-j9kg00qf 5763 1 An an DT cord-022526-j9kg00qf 5763 2 analysis analysis NN cord-022526-j9kg00qf 5763 3 of of IN cord-022526-j9kg00qf 5763 4 75 75 CD cord-022526-j9kg00qf 5763 5 cases case NNS cord-022526-j9kg00qf 5763 6 of of IN cord-022526-j9kg00qf 5763 7 intestinal intestinal JJ cord-022526-j9kg00qf 5763 8 obstruction obstruction NN cord-022526-j9kg00qf 5763 9 caused cause VBN cord-022526-j9kg00qf 5763 10 by by IN cord-022526-j9kg00qf 5763 11 pedunculated pedunculate VBN cord-022526-j9kg00qf 5763 12 lipomas lipoma NNS cord-022526-j9kg00qf 5763 13 Rectal rectal JJ cord-022526-j9kg00qf 5763 14 leiomyosarcoma leiomyosarcoma NN cord-022526-j9kg00qf 5763 15 in in IN cord-022526-j9kg00qf 5763 16 a a DT cord-022526-j9kg00qf 5763 17 horse horse NN cord-022526-j9kg00qf 5763 18 Strangulation strangulation NN cord-022526-j9kg00qf 5763 19 of of IN cord-022526-j9kg00qf 5763 20 the the DT cord-022526-j9kg00qf 5763 21 rectum rectum NN cord-022526-j9kg00qf 5763 22 of of IN cord-022526-j9kg00qf 5763 23 a a DT cord-022526-j9kg00qf 5763 24 horse horse NN cord-022526-j9kg00qf 5763 25 by by IN cord-022526-j9kg00qf 5763 26 the the DT cord-022526-j9kg00qf 5763 27 pedicle pedicle NN cord-022526-j9kg00qf 5763 28 of of IN cord-022526-j9kg00qf 5763 29 a a DT cord-022526-j9kg00qf 5763 30 mesenteric mesenteric JJ cord-022526-j9kg00qf 5763 31 lipoma lipoma NN cord-022526-j9kg00qf 5763 32 Rectal rectal JJ cord-022526-j9kg00qf 5763 33 biopsy biopsy NN cord-022526-j9kg00qf 5763 34 diagnosis diagnosis NN cord-022526-j9kg00qf 5763 35 in in IN cord-022526-j9kg00qf 5763 36 horses horse NNS cord-022526-j9kg00qf 5763 37 with with IN cord-022526-j9kg00qf 5763 38 clinical clinical JJ cord-022526-j9kg00qf 5763 39 signs sign NNS cord-022526-j9kg00qf 5763 40 of of IN cord-022526-j9kg00qf 5763 41 intestinal intestinal JJ cord-022526-j9kg00qf 5763 42 disorders disorder NNS cord-022526-j9kg00qf 5763 43 : : : cord-022526-j9kg00qf 5763 44 a a DT cord-022526-j9kg00qf 5763 45 retrospective retrospective JJ cord-022526-j9kg00qf 5763 46 study study NN cord-022526-j9kg00qf 5763 47 of of IN cord-022526-j9kg00qf 5763 48 116 116 CD cord-022526-j9kg00qf 5763 49 cases case NNS cord-022526-j9kg00qf 5764 1 Standing stand VBG cord-022526-j9kg00qf 5764 2 rectal rectal NN cord-022526-j9kg00qf 5764 3 and and CC cord-022526-j9kg00qf 5764 4 tail tail NN cord-022526-j9kg00qf 5764 5 surgery surgery NN cord-022526-j9kg00qf 5764 6 Disseminated disseminate VBD cord-022526-j9kg00qf 5764 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 5764 8 leiomyomatosis leiomyomatosis NN cord-022526-j9kg00qf 5764 9 in in IN cord-022526-j9kg00qf 5764 10 a a DT cord-022526-j9kg00qf 5764 11 horse horse NN cord-022526-j9kg00qf 5764 12 Ascites Ascites NNPS cord-022526-j9kg00qf 5764 13 as as IN cord-022526-j9kg00qf 5764 14 a a DT cord-022526-j9kg00qf 5764 15 result result NN cord-022526-j9kg00qf 5764 16 of of IN cord-022526-j9kg00qf 5764 17 peritoneal peritoneal JJ cord-022526-j9kg00qf 5764 18 mesotheliomas mesotheliomas NN cord-022526-j9kg00qf 5764 19 in in IN cord-022526-j9kg00qf 5764 20 a a DT cord-022526-j9kg00qf 5764 21 horse horse NN cord-022526-j9kg00qf 5764 22 A a DT cord-022526-j9kg00qf 5764 23 case case NN cord-022526-j9kg00qf 5764 24 of of IN cord-022526-j9kg00qf 5764 25 peritoneal peritoneal JJ cord-022526-j9kg00qf 5764 26 mesothelioma mesothelioma NN cord-022526-j9kg00qf 5764 27 in in IN cord-022526-j9kg00qf 5764 28 a a DT cord-022526-j9kg00qf 5764 29 thoroughbred thoroughbred JJ cord-022526-j9kg00qf 5764 30 mare mare NN cord-022526-j9kg00qf 5764 31 Omental Omental NNP cord-022526-j9kg00qf 5764 32 fibrosarcoma fibrosarcoma NNS cord-022526-j9kg00qf 5764 33 in in IN cord-022526-j9kg00qf 5764 34 a a DT cord-022526-j9kg00qf 5764 35 horse horse NN cord-022526-j9kg00qf 5764 36 Neoplasia neoplasia NN cord-022526-j9kg00qf 5764 37 of of IN cord-022526-j9kg00qf 5764 38 the the DT cord-022526-j9kg00qf 5764 39 mouth mouth NN cord-022526-j9kg00qf 5764 40 and and CC cord-022526-j9kg00qf 5764 41 surrounding surround VBG cord-022526-j9kg00qf 5764 42 structure structure NN cord-022526-j9kg00qf 5765 1 Pleuroscopic Pleuroscopic NNP cord-022526-j9kg00qf 5765 2 diagnosis diagnosis NN cord-022526-j9kg00qf 5765 3 of of IN cord-022526-j9kg00qf 5765 4 gastroesophageal gastroesophageal JJ cord-022526-j9kg00qf 5765 5 squamous squamous JJ cord-022526-j9kg00qf 5765 6 cell cell NN cord-022526-j9kg00qf 5765 7 carcinoma carcinoma NN cord-022526-j9kg00qf 5765 8 in in IN cord-022526-j9kg00qf 5765 9 a a DT cord-022526-j9kg00qf 5765 10 horse horse NN cord-022526-j9kg00qf 5765 11 Recurrent recurrent JJ cord-022526-j9kg00qf 5765 12 esophageal esophageal JJ cord-022526-j9kg00qf 5765 13 obstruction obstruction NN cord-022526-j9kg00qf 5765 14 due due JJ cord-022526-j9kg00qf 5765 15 to to IN cord-022526-j9kg00qf 5765 16 squamous squamous JJ cord-022526-j9kg00qf 5765 17 cell cell NN cord-022526-j9kg00qf 5765 18 carcinoma carcinoma NN cord-022526-j9kg00qf 5765 19 in in IN cord-022526-j9kg00qf 5765 20 a a DT cord-022526-j9kg00qf 5765 21 horse horse NN cord-022526-j9kg00qf 5765 22 Chronic Chronic NNP cord-022526-j9kg00qf 5765 23 colic colic NN cord-022526-j9kg00qf 5765 24 in in IN cord-022526-j9kg00qf 5765 25 the the DT cord-022526-j9kg00qf 5765 26 mature mature JJ cord-022526-j9kg00qf 5765 27 horse horse NN cord-022526-j9kg00qf 5765 28 : : : cord-022526-j9kg00qf 5766 1 a a DT cord-022526-j9kg00qf 5766 2 retrospective retrospective JJ cord-022526-j9kg00qf 5766 3 review review NN cord-022526-j9kg00qf 5766 4 of of IN cord-022526-j9kg00qf 5766 5 106 106 CD cord-022526-j9kg00qf 5766 6 cases case NNS cord-022526-j9kg00qf 5767 1 Recurrent recurrent JJ cord-022526-j9kg00qf 5767 2 colic colic NN cord-022526-j9kg00qf 5767 3 in in IN cord-022526-j9kg00qf 5767 4 the the DT cord-022526-j9kg00qf 5767 5 mature mature JJ cord-022526-j9kg00qf 5767 6 horse horse NN cord-022526-j9kg00qf 5767 7 : : : cord-022526-j9kg00qf 5768 1 a a DT cord-022526-j9kg00qf 5768 2 retrospective retrospective JJ cord-022526-j9kg00qf 5768 3 review review NN cord-022526-j9kg00qf 5768 4 of of IN cord-022526-j9kg00qf 5768 5 58 58 CD cord-022526-j9kg00qf 5768 6 cases case NNS cord-022526-j9kg00qf 5768 7 Paraneoplastic paraneoplastic JJ cord-022526-j9kg00qf 5768 8 syndromes syndrome NNS cord-022526-j9kg00qf 5769 1 Lymphosarcoma Lymphosarcoma NNP cord-022526-j9kg00qf 5769 2 and and CC cord-022526-j9kg00qf 5769 3 associated associate VBD cord-022526-j9kg00qf 5769 4 immune immune NN cord-022526-j9kg00qf 5769 5 - - HYPH cord-022526-j9kg00qf 5769 6 mediated mediate VBN cord-022526-j9kg00qf 5769 7 hemolytic hemolytic JJ cord-022526-j9kg00qf 5769 8 anemia anemia NN cord-022526-j9kg00qf 5769 9 and and CC cord-022526-j9kg00qf 5769 10 thrombocytopenia thrombocytopenia NN cord-022526-j9kg00qf 5769 11 in in IN cord-022526-j9kg00qf 5769 12 horses horse NNS cord-022526-j9kg00qf 5769 13 Differentiation differentiation NN cord-022526-j9kg00qf 5769 14 of of IN cord-022526-j9kg00qf 5769 15 chronic chronic JJ cord-022526-j9kg00qf 5769 16 lymphocytic lymphocytic JJ cord-022526-j9kg00qf 5769 17 leukemia leukemia NN cord-022526-j9kg00qf 5769 18 in in IN cord-022526-j9kg00qf 5769 19 the the DT cord-022526-j9kg00qf 5769 20 horse horse NN cord-022526-j9kg00qf 5769 21 : : : cord-022526-j9kg00qf 5769 22 a a DT cord-022526-j9kg00qf 5769 23 report report NN cord-022526-j9kg00qf 5769 24 of of IN cord-022526-j9kg00qf 5769 25 two two CD cord-022526-j9kg00qf 5769 26 cases case NNS cord-022526-j9kg00qf 5769 27 Hypercalcemia Hypercalcemia NNP cord-022526-j9kg00qf 5769 28 associated associate VBN cord-022526-j9kg00qf 5769 29 with with IN cord-022526-j9kg00qf 5769 30 malignancy malignancy NN cord-022526-j9kg00qf 5769 31 in in IN cord-022526-j9kg00qf 5769 32 a a DT cord-022526-j9kg00qf 5769 33 horse horse NN cord-022526-j9kg00qf 5769 34 Adenocarcinoma Adenocarcinoma NNP cord-022526-j9kg00qf 5769 35 of of IN cord-022526-j9kg00qf 5769 36 intestinal intestinal JJ cord-022526-j9kg00qf 5769 37 origin origin NN cord-022526-j9kg00qf 5769 38 in in IN cord-022526-j9kg00qf 5769 39 a a DT cord-022526-j9kg00qf 5769 40 horse horse NN cord-022526-j9kg00qf 5769 41 : : : cord-022526-j9kg00qf 5769 42 diagnosis diagnosis NN cord-022526-j9kg00qf 5769 43 by by IN cord-022526-j9kg00qf 5769 44 abdominocentesis abdominocentesis NN cord-022526-j9kg00qf 5769 45 and and CC cord-022526-j9kg00qf 5769 46 laparoscopy laparoscopy JJ cord-022526-j9kg00qf 5769 47 Differentiation differentiation NN cord-022526-j9kg00qf 5769 48 between between IN cord-022526-j9kg00qf 5769 49 intra intra JJ cord-022526-j9kg00qf 5769 50 - - JJ cord-022526-j9kg00qf 5769 51 abdominal abdominal JJ cord-022526-j9kg00qf 5769 52 neoplasms neoplasm NNS cord-022526-j9kg00qf 5769 53 and and CC cord-022526-j9kg00qf 5769 54 abscesses abscess NNS cord-022526-j9kg00qf 5769 55 in in IN cord-022526-j9kg00qf 5769 56 horses horse NNS cord-022526-j9kg00qf 5769 57 , , , cord-022526-j9kg00qf 5769 58 using use VBG cord-022526-j9kg00qf 5769 59 clinical clinical JJ cord-022526-j9kg00qf 5769 60 and and CC cord-022526-j9kg00qf 5769 61 laboratory laboratory NN cord-022526-j9kg00qf 5769 62 data datum NNS cord-022526-j9kg00qf 5769 63 : : : cord-022526-j9kg00qf 5769 64 40 40 CD cord-022526-j9kg00qf 5769 65 cases case NNS cord-022526-j9kg00qf 5769 66 ( ( -LRB- cord-022526-j9kg00qf 5769 67 1973 1973 CD cord-022526-j9kg00qf 5769 68 - - SYM cord-022526-j9kg00qf 5769 69 1988 1988 CD cord-022526-j9kg00qf 5769 70 ) ) -RRB- cord-022526-j9kg00qf 5770 1 Malabsorption malabsorption NN cord-022526-j9kg00qf 5770 2 in in IN cord-022526-j9kg00qf 5770 3 the the DT cord-022526-j9kg00qf 5770 4 horse horse NN cord-022526-j9kg00qf 5770 5 associated associate VBN cord-022526-j9kg00qf 5770 6 with with IN cord-022526-j9kg00qf 5770 7 alimentary alimentary JJ cord-022526-j9kg00qf 5770 8 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5770 9 Immunodeficiency Immunodeficiency NNP cord-022526-j9kg00qf 5770 10 associated associate VBN cord-022526-j9kg00qf 5770 11 with with IN cord-022526-j9kg00qf 5770 12 lymphosarcoma lymphosarcoma NNP cord-022526-j9kg00qf 5770 13 in in IN cord-022526-j9kg00qf 5770 14 a a DT cord-022526-j9kg00qf 5770 15 horse horse NN cord-022526-j9kg00qf 5770 16 Flow flow NN cord-022526-j9kg00qf 5770 17 cytometric cytometric NN cord-022526-j9kg00qf 5770 18 methods method NNS cord-022526-j9kg00qf 5770 19 to to TO cord-022526-j9kg00qf 5770 20 diagnose diagnose VB cord-022526-j9kg00qf 5770 21 selected select VBN cord-022526-j9kg00qf 5770 22 equine equine JJ cord-022526-j9kg00qf 5770 23 immune immune NN cord-022526-j9kg00qf 5770 24 - - HYPH cord-022526-j9kg00qf 5770 25 mediated mediate VBN cord-022526-j9kg00qf 5770 26 disorders disorder NNS cord-022526-j9kg00qf 5770 27 Pleural Pleural NNP cord-022526-j9kg00qf 5770 28 effusion effusion NN cord-022526-j9kg00qf 5770 29 associated associate VBN cord-022526-j9kg00qf 5770 30 with with IN cord-022526-j9kg00qf 5770 31 squamous squamous JJ cord-022526-j9kg00qf 5770 32 cell cell NN cord-022526-j9kg00qf 5770 33 carcinoma carcinoma NN cord-022526-j9kg00qf 5770 34 of of IN cord-022526-j9kg00qf 5770 35 the the DT cord-022526-j9kg00qf 5770 36 stomach stomach NN cord-022526-j9kg00qf 5770 37 of of IN cord-022526-j9kg00qf 5770 38 a a DT cord-022526-j9kg00qf 5770 39 horse horse NN cord-022526-j9kg00qf 5770 40 Use use NN cord-022526-j9kg00qf 5770 41 of of IN cord-022526-j9kg00qf 5770 42 diagnostic diagnostic JJ cord-022526-j9kg00qf 5770 43 ultrasonography ultrasonography NN cord-022526-j9kg00qf 5770 44 in in IN cord-022526-j9kg00qf 5770 45 horses horse NNS cord-022526-j9kg00qf 5770 46 with with IN cord-022526-j9kg00qf 5770 47 signs sign NNS cord-022526-j9kg00qf 5770 48 of of IN cord-022526-j9kg00qf 5770 49 acute acute JJ cord-022526-j9kg00qf 5770 50 abdominal abdominal JJ cord-022526-j9kg00qf 5770 51 pain pain NN cord-022526-j9kg00qf 5771 1 The the DT cord-022526-j9kg00qf 5771 2 indications indication NNS cord-022526-j9kg00qf 5771 3 for for IN cord-022526-j9kg00qf 5771 4 equine equine JJ cord-022526-j9kg00qf 5771 5 laparotomy laparotomy NN cord-022526-j9kg00qf 5771 6 : : : cord-022526-j9kg00qf 5771 7 an an DT cord-022526-j9kg00qf 5771 8 analysis analysis NN cord-022526-j9kg00qf 5771 9 of of IN cord-022526-j9kg00qf 5771 10 140 140 CD cord-022526-j9kg00qf 5771 11 cases case NNS cord-022526-j9kg00qf 5771 12 Equine equine NN cord-022526-j9kg00qf 5771 13 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 5771 14 Diarrhoea diarrhoea NN cord-022526-j9kg00qf 5771 15 in in IN cord-022526-j9kg00qf 5771 16 the the DT cord-022526-j9kg00qf 5771 17 horse horse NN cord-022526-j9kg00qf 5771 18 as as IN cord-022526-j9kg00qf 5771 19 a a DT cord-022526-j9kg00qf 5771 20 result result NN cord-022526-j9kg00qf 5771 21 of of IN cord-022526-j9kg00qf 5771 22 alimentary alimentary JJ cord-022526-j9kg00qf 5771 23 lymphosarcoma lymphosarcoma NN cord-022526-j9kg00qf 5771 24 Paraneoplastic paraneoplastic JJ cord-022526-j9kg00qf 5771 25 pruritus pruritus NN cord-022526-j9kg00qf 5771 26 and and CC cord-022526-j9kg00qf 5771 27 alopecia alopecia NN cord-022526-j9kg00qf 5771 28 in in IN cord-022526-j9kg00qf 5771 29 a a DT cord-022526-j9kg00qf 5771 30 horse horse NN cord-022526-j9kg00qf 5771 31 with with IN cord-022526-j9kg00qf 5771 32 diffuse diffuse JJ cord-022526-j9kg00qf 5771 33 lymphoma lymphoma NN cord-022526-j9kg00qf 5771 34 Lymphoma Lymphoma NNP cord-022526-j9kg00qf 5771 35 in in IN cord-022526-j9kg00qf 5771 36 the the DT cord-022526-j9kg00qf 5771 37 horse horse NN cord-022526-j9kg00qf 5771 38 . . . cord-022526-j9kg00qf 5772 1 Proceedings proceeding NNS cord-022526-j9kg00qf 5772 2 of of IN cord-022526-j9kg00qf 5772 3 the the DT cord-022526-j9kg00qf 5772 4 twelfth twelfth JJ cord-022526-j9kg00qf 5772 5 annual annual JJ cord-022526-j9kg00qf 5772 6 meeting meeting NN cord-022526-j9kg00qf 5772 7 of of IN cord-022526-j9kg00qf 5772 8 the the DT cord-022526-j9kg00qf 5772 9 American American NNP cord-022526-j9kg00qf 5772 10 College College NNP cord-022526-j9kg00qf 5772 11 of of IN cord-022526-j9kg00qf 5772 12 Veterinary Veterinary NNP cord-022526-j9kg00qf 5772 13 Internal Internal NNP cord-022526-j9kg00qf 5772 14 Medicine Medicine NNP cord-022526-j9kg00qf 5772 15 Squamous squamous JJ cord-022526-j9kg00qf 5772 16 cell cell NN cord-022526-j9kg00qf 5772 17 carcinoma carcinoma NN cord-022526-j9kg00qf 5772 18 of of IN cord-022526-j9kg00qf 5772 19 the the DT cord-022526-j9kg00qf 5772 20 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 5772 21 wall wall NN cord-022526-j9kg00qf 5772 22 in in IN cord-022526-j9kg00qf 5772 23 a a DT cord-022526-j9kg00qf 5772 24 horse horse NN cord-022526-j9kg00qf 5772 25 Squamous squamous JJ cord-022526-j9kg00qf 5772 26 cell cell NN cord-022526-j9kg00qf 5772 27 carcinoma carcinoma NN cord-022526-j9kg00qf 5772 28 of of IN cord-022526-j9kg00qf 5772 29 the the DT cord-022526-j9kg00qf 5772 30 oral oral JJ cord-022526-j9kg00qf 5772 31 , , , cord-022526-j9kg00qf 5772 32 pharyngeal pharyngeal JJ cord-022526-j9kg00qf 5772 33 and and CC cord-022526-j9kg00qf 5772 34 nasal nasal JJ cord-022526-j9kg00qf 5772 35 mucosa mucosa NN cord-022526-j9kg00qf 5772 36 in in IN cord-022526-j9kg00qf 5772 37 the the DT cord-022526-j9kg00qf 5772 38 horse horse NN cord-022526-j9kg00qf 5772 39 Treatment treatment NN cord-022526-j9kg00qf 5772 40 of of IN cord-022526-j9kg00qf 5772 41 superficial superficial JJ cord-022526-j9kg00qf 5772 42 ulcerative ulcerative JJ cord-022526-j9kg00qf 5772 43 squamous squamous JJ cord-022526-j9kg00qf 5772 44 cell cell NN cord-022526-j9kg00qf 5772 45 carcinoma carcinoma NN cord-022526-j9kg00qf 5772 46 in in IN cord-022526-j9kg00qf 5772 47 three three CD cord-022526-j9kg00qf 5772 48 horses horse NNS cord-022526-j9kg00qf 5772 49 with with IN cord-022526-j9kg00qf 5772 50 topical topical JJ cord-022526-j9kg00qf 5772 51 5-fluorouracil 5-fluorouracil CD cord-022526-j9kg00qf 5772 52 Intratumoral Intratumoral NNP cord-022526-j9kg00qf 5772 53 chemotherapy chemotherapy NN cord-022526-j9kg00qf 5772 54 with with IN cord-022526-j9kg00qf 5772 55 cisplatin cisplatin NN cord-022526-j9kg00qf 5772 56 in in IN cord-022526-j9kg00qf 5772 57 oily oily JJ cord-022526-j9kg00qf 5772 58 emulsion emulsion NN cord-022526-j9kg00qf 5772 59 in in IN cord-022526-j9kg00qf 5772 60 horses horse NNS cord-022526-j9kg00qf 5772 61 Excision excision NN cord-022526-j9kg00qf 5772 62 of of IN cord-022526-j9kg00qf 5772 63 oral oral JJ cord-022526-j9kg00qf 5772 64 squamous squamous JJ cord-022526-j9kg00qf 5772 65 cell cell NN cord-022526-j9kg00qf 5772 66 carcinoma carcinoma NN cord-022526-j9kg00qf 5772 67 in in IN cord-022526-j9kg00qf 5772 68 a a DT cord-022526-j9kg00qf 5772 69 horse horse NN cord-022526-j9kg00qf 5772 70 Extensive extensive JJ cord-022526-j9kg00qf 5772 71 resection resection NN cord-022526-j9kg00qf 5772 72 and and CC cord-022526-j9kg00qf 5772 73 anastomosis anastomosis NN cord-022526-j9kg00qf 5772 74 of of IN cord-022526-j9kg00qf 5772 75 the the DT cord-022526-j9kg00qf 5772 76 descending descend VBG cord-022526-j9kg00qf 5772 77 ( ( -LRB- cord-022526-j9kg00qf 5772 78 small small JJ cord-022526-j9kg00qf 5772 79 ) ) -RRB- cord-022526-j9kg00qf 5772 80 colon colon NN cord-022526-j9kg00qf 5772 81 in in IN cord-022526-j9kg00qf 5772 82 a a DT cord-022526-j9kg00qf 5772 83 mare mare NN cord-022526-j9kg00qf 5772 84 following follow VBG cord-022526-j9kg00qf 5772 85 strangulation strangulation NN cord-022526-j9kg00qf 5772 86 by by IN cord-022526-j9kg00qf 5772 87 a a DT cord-022526-j9kg00qf 5772 88 mesenteric mesenteric JJ cord-022526-j9kg00qf 5772 89 lipoma lipoma NN cord-022526-j9kg00qf 5772 90 SECTION section NN cord-022526-j9kg00qf 5772 91 13.17 13.17 CD cord-022526-j9kg00qf 5772 92 Peritonitis peritonitis NN cord-022526-j9kg00qf 5772 93 REFERENCES reference NNS cord-022526-j9kg00qf 5772 94 1 1 CD cord-022526-j9kg00qf 5772 95 . . . cord-022526-j9kg00qf 5773 1 Hosgood Hosgood NNP cord-022526-j9kg00qf 5773 2 G G NNP cord-022526-j9kg00qf 5773 3 : : : cord-022526-j9kg00qf 5773 4 Peritonitis peritonitis NN cord-022526-j9kg00qf 5773 5 . . . cord-022526-j9kg00qf 5774 1 1 1 LS cord-022526-j9kg00qf 5774 2 . . . cord-022526-j9kg00qf 5775 1 A a DT cord-022526-j9kg00qf 5775 2 review review NN cord-022526-j9kg00qf 5775 3 of of IN cord-022526-j9kg00qf 5775 4 the the DT cord-022526-j9kg00qf 5775 5 pathophysiology pathophysiology NN cord-022526-j9kg00qf 5775 6 and and CC cord-022526-j9kg00qf 5775 7 diagnosis diagnosis NN cord-022526-j9kg00qf 5776 1 The the DT cord-022526-j9kg00qf 5776 2 peritoneum peritoneum NN cord-022526-j9kg00qf 5776 3 and and CC cord-022526-j9kg00qf 5776 4 peritoneal peritoneal NN cord-022526-j9kg00qf 5776 5 cavity cavity NN cord-022526-j9kg00qf 5776 6 Large large JJ cord-022526-j9kg00qf 5776 7 animal animal NN cord-022526-j9kg00qf 5776 8 internal internal JJ cord-022526-j9kg00qf 5776 9 medicine medicine NN cord-022526-j9kg00qf 5776 10 Diseases disease NNS cord-022526-j9kg00qf 5776 11 of of IN cord-022526-j9kg00qf 5776 12 the the DT cord-022526-j9kg00qf 5776 13 peritoneum peritoneum NN cord-022526-j9kg00qf 5776 14 and and CC cord-022526-j9kg00qf 5776 15 mesentery mesentery NN cord-022526-j9kg00qf 5776 16 Equine equine NN cord-022526-j9kg00qf 5777 1 internal internal JJ cord-022526-j9kg00qf 5777 2 medicine medicine NN cord-022526-j9kg00qf 5777 3 Peritonitis Peritonitis NNP cord-022526-j9kg00qf 5777 4 associated associate VBN cord-022526-j9kg00qf 5777 5 with with IN cord-022526-j9kg00qf 5777 6 Actinobacillus Actinobacillus NNP cord-022526-j9kg00qf 5777 7 equuli equuli NNP cord-022526-j9kg00qf 5777 8 in in IN cord-022526-j9kg00qf 5777 9 horses horse NNS cord-022526-j9kg00qf 5777 10 : : : cord-022526-j9kg00qf 5777 11 51 51 CD cord-022526-j9kg00qf 5777 12 cases case NNS cord-022526-j9kg00qf 5777 13 Veterinary veterinary JJ cord-022526-j9kg00qf 5777 14 gastroenterology gastroenterology NN cord-022526-j9kg00qf 5777 15 Peritonitis peritonitis NN cord-022526-j9kg00qf 5777 16 and and CC cord-022526-j9kg00qf 5777 17 other other JJ cord-022526-j9kg00qf 5777 18 intra intra JJ cord-022526-j9kg00qf 5777 19 - - JJ cord-022526-j9kg00qf 5777 20 abdominal abdominal JJ cord-022526-j9kg00qf 5777 21 infection infection NN cord-022526-j9kg00qf 5777 22 Antibiotic antibiotic JJ cord-022526-j9kg00qf 5777 23 susceptibility susceptibility NN cord-022526-j9kg00qf 5777 24 of of IN cord-022526-j9kg00qf 5777 25 bacterial bacterial JJ cord-022526-j9kg00qf 5777 26 pathogens pathogen NNS cord-022526-j9kg00qf 5777 27 from from IN cord-022526-j9kg00qf 5777 28 horses horse NNS cord-022526-j9kg00qf 5777 29 Peritonitis peritonitis NN cord-022526-j9kg00qf 5777 30 in in IN cord-022526-j9kg00qf 5777 31 horses horse NNS cord-022526-j9kg00qf 5777 32 : : : cord-022526-j9kg00qf 5778 1 67 67 CD cord-022526-j9kg00qf 5778 2 cases case NNS cord-022526-j9kg00qf 5778 3 Biologic biologic JJ cord-022526-j9kg00qf 5778 4 reactions reaction NNS cord-022526-j9kg00qf 5778 5 to to TO cord-022526-j9kg00qf 5778 6 endotoxin endotoxin NN cord-022526-j9kg00qf 5778 7 Effect effect NN cord-022526-j9kg00qf 5778 8 of of IN cord-022526-j9kg00qf 5778 9 dietary dietary JJ cord-022526-j9kg00qf 5778 10 alpha alpha NN cord-022526-j9kg00qf 5778 11 - - HYPH cord-022526-j9kg00qf 5778 12 linoleic linoleic NN cord-022526-j9kg00qf 5778 13 acid acid NN cord-022526-j9kg00qf 5778 14 on on IN cord-022526-j9kg00qf 5778 15 equine equine JJ cord-022526-j9kg00qf 5778 16 monocyte monocyte NNP cord-022526-j9kg00qf 5778 17 procoagulant procoagulant NNP cord-022526-j9kg00qf 5778 18 activity activity NNP cord-022526-j9kg00qf 5778 19 and and CC cord-022526-j9kg00qf 5778 20 eicosanoid eicosanoid NNP cord-022526-j9kg00qf 5778 21 synthesis synthesis NN cord-022526-j9kg00qf 5778 22 Review Review NNP cord-022526-j9kg00qf 5778 23 of of IN cord-022526-j9kg00qf 5778 24 30 30 CD cord-022526-j9kg00qf 5778 25 cases case NNS cord-022526-j9kg00qf 5778 26 of of IN cord-022526-j9kg00qf 5778 27 peritonitis peritonitis NN cord-022526-j9kg00qf 5778 28 in in IN cord-022526-j9kg00qf 5778 29 the the DT cord-022526-j9kg00qf 5778 30 horse horse NN cord-022526-j9kg00qf 5778 31 Reference reference NN cord-022526-j9kg00qf 5778 32 values value NNS cord-022526-j9kg00qf 5778 33 for for IN cord-022526-j9kg00qf 5778 34 equine equine JJ cord-022526-j9kg00qf 5778 35 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 36 fluid fluid NN cord-022526-j9kg00qf 5778 37 Diagnostic diagnostic JJ cord-022526-j9kg00qf 5778 38 cytology cytology NN cord-022526-j9kg00qf 5778 39 in in IN cord-022526-j9kg00qf 5778 40 the the DT cord-022526-j9kg00qf 5778 41 equine equine JJ cord-022526-j9kg00qf 5778 42 species specie NNS cord-022526-j9kg00qf 5778 43 : : : cord-022526-j9kg00qf 5778 44 overview overview NN cord-022526-j9kg00qf 5778 45 of of IN cord-022526-j9kg00qf 5778 46 effusions effusion NNS cord-022526-j9kg00qf 5778 47 ( ( -LRB- cord-022526-j9kg00qf 5778 48 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 49 , , , cord-022526-j9kg00qf 5778 50 pleural pleural JJ cord-022526-j9kg00qf 5778 51 , , , cord-022526-j9kg00qf 5778 52 and and CC cord-022526-j9kg00qf 5778 53 synovial synovial JJ cord-022526-j9kg00qf 5778 54 joint joint NN cord-022526-j9kg00qf 5778 55 ) ) -RRB- cord-022526-j9kg00qf 5778 56 and and CC cord-022526-j9kg00qf 5778 57 transtracheal transtracheal NN cord-022526-j9kg00qf 5778 58 wash wash NN cord-022526-j9kg00qf 5778 59 Effects effect NNS cord-022526-j9kg00qf 5778 60 of of IN cord-022526-j9kg00qf 5778 61 enterocentesis enterocentesis NN cord-022526-j9kg00qf 5778 62 on on IN cord-022526-j9kg00qf 5778 63 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 64 fluid fluid JJ cord-022526-j9kg00qf 5778 65 constituents constituent NNS cord-022526-j9kg00qf 5778 66 in in IN cord-022526-j9kg00qf 5778 67 the the DT cord-022526-j9kg00qf 5778 68 horse horse NN cord-022526-j9kg00qf 5778 69 Internal internal JJ cord-022526-j9kg00qf 5778 70 abdominal abdominal JJ cord-022526-j9kg00qf 5778 71 abscesses abscess NNS cord-022526-j9kg00qf 5778 72 in in IN cord-022526-j9kg00qf 5778 73 the the DT cord-022526-j9kg00qf 5778 74 horse horse NN cord-022526-j9kg00qf 5778 75 : : : cord-022526-j9kg00qf 5778 76 a a DT cord-022526-j9kg00qf 5778 77 study study NN cord-022526-j9kg00qf 5778 78 of of IN cord-022526-j9kg00qf 5778 79 25 25 CD cord-022526-j9kg00qf 5778 80 cases case NNS cord-022526-j9kg00qf 5778 81 Equine equine JJ cord-022526-j9kg00qf 5778 82 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 83 fluid fluid NN cord-022526-j9kg00qf 5778 84 analysis analysis NN cord-022526-j9kg00qf 5778 85 following follow VBG cord-022526-j9kg00qf 5778 86 celiotomy celiotomy NNP cord-022526-j9kg00qf 5778 87 Analysis Analysis NNP cord-022526-j9kg00qf 5778 88 of of IN cord-022526-j9kg00qf 5778 89 equine equine JJ cord-022526-j9kg00qf 5778 90 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 91 fluid fluid NN cord-022526-j9kg00qf 5778 92 Evaluation Evaluation NNP cord-022526-j9kg00qf 5778 93 of of IN cord-022526-j9kg00qf 5778 94 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 95 fluid fluid NN cord-022526-j9kg00qf 5778 96 pH ph NN cord-022526-j9kg00qf 5778 97 , , , cord-022526-j9kg00qf 5778 98 glucose glucose NN cord-022526-j9kg00qf 5778 99 concentration concentration NN cord-022526-j9kg00qf 5778 100 , , , cord-022526-j9kg00qf 5778 101 and and CC cord-022526-j9kg00qf 5778 102 lactate lactate NN cord-022526-j9kg00qf 5778 103 dehydrogenase dehydrogenase NN cord-022526-j9kg00qf 5778 104 activity activity NN cord-022526-j9kg00qf 5778 105 for for IN cord-022526-j9kg00qf 5778 106 detection detection NN cord-022526-j9kg00qf 5778 107 of of IN cord-022526-j9kg00qf 5778 108 septic septic JJ cord-022526-j9kg00qf 5778 109 peritonitis peritonitis NN cord-022526-j9kg00qf 5778 110 in in IN cord-022526-j9kg00qf 5778 111 horses horse NNS cord-022526-j9kg00qf 5778 112 Tumor tumor NN cord-022526-j9kg00qf 5778 113 necrosis necrosis NN cord-022526-j9kg00qf 5778 114 factor factor NN cord-022526-j9kg00qf 5778 115 and and CC cord-022526-j9kg00qf 5778 116 interleukin-6 interleukin-6 NNP cord-022526-j9kg00qf 5778 117 activity activity NN cord-022526-j9kg00qf 5778 118 and and CC cord-022526-j9kg00qf 5778 119 endotoxin endotoxin NN cord-022526-j9kg00qf 5778 120 concentration concentration NN cord-022526-j9kg00qf 5778 121 in in IN cord-022526-j9kg00qf 5778 122 peritoneal peritoneal JJ cord-022526-j9kg00qf 5778 123 fluid fluid NN cord-022526-j9kg00qf 5778 124 and and CC cord-022526-j9kg00qf 5778 125 blood blood NN cord-022526-j9kg00qf 5778 126 of of IN cord-022526-j9kg00qf 5778 127 horses horse NNS cord-022526-j9kg00qf 5778 128 with with IN cord-022526-j9kg00qf 5778 129 acute acute JJ cord-022526-j9kg00qf 5778 130 abdominal abdominal JJ cord-022526-j9kg00qf 5778 131 disease disease NN cord-022526-j9kg00qf 5779 1 Low low JJ cord-022526-j9kg00qf 5779 2 dose dose NN cord-022526-j9kg00qf 5779 3 flunixin flunixin NNP cord-022526-j9kg00qf 5779 4 meglumine meglumine NN cord-022526-j9kg00qf 5779 5 : : : cord-022526-j9kg00qf 5779 6 effects effect NNS cord-022526-j9kg00qf 5779 7 on on IN cord-022526-j9kg00qf 5779 8 eicosanoid eicosanoid JJ cord-022526-j9kg00qf 5779 9 production production NN cord-022526-j9kg00qf 5779 10 and and CC cord-022526-j9kg00qf 5779 11 clinical clinical JJ cord-022526-j9kg00qf 5779 12 signs sign NNS cord-022526-j9kg00qf 5779 13 induced induce VBN cord-022526-j9kg00qf 5779 14 by by IN cord-022526-j9kg00qf 5779 15 experimental experimental JJ cord-022526-j9kg00qf 5779 16 endotoxemia endotoxemia NN cord-022526-j9kg00qf 5779 17 in in IN cord-022526-j9kg00qf 5779 18 horses horse NNS cord-022526-j9kg00qf 5779 19 Heparin Heparin VBN cord-022526-j9kg00qf 5779 20 in in IN cord-022526-j9kg00qf 5779 21 the the DT cord-022526-j9kg00qf 5779 22 treatment treatment NN cord-022526-j9kg00qf 5779 23 of of IN cord-022526-j9kg00qf 5779 24 experimental experimental JJ cord-022526-j9kg00qf 5779 25 peritonitis peritonitis NN cord-022526-j9kg00qf 5779 26 Erythrocyte Erythrocyte NNP cord-022526-j9kg00qf 5779 27 agglutination agglutination NN cord-022526-j9kg00qf 5779 28 associated associate VBN cord-022526-j9kg00qf 5779 29 with with IN cord-022526-j9kg00qf 5779 30 heparin heparin JJ cord-022526-j9kg00qf 5779 31 treatment treatment NN cord-022526-j9kg00qf 5779 32 in in IN cord-022526-j9kg00qf 5779 33 three three CD cord-022526-j9kg00qf 5779 34 horses horse NNS cord-022526-j9kg00qf 5779 35 Therapeutic therapeutic JJ cord-022526-j9kg00qf 5779 36 strategies strategy NNS cord-022526-j9kg00qf 5779 37 involving involve VBG cord-022526-j9kg00qf 5779 38 antimicrobial antimicrobial JJ cord-022526-j9kg00qf 5779 39 treatment treatment NN cord-022526-j9kg00qf 5779 40 of of IN cord-022526-j9kg00qf 5779 41 large large JJ cord-022526-j9kg00qf 5779 42 animals animal NNS cord-022526-j9kg00qf 5779 43 with with IN cord-022526-j9kg00qf 5779 44 peritonitis peritonitis NN cord-022526-j9kg00qf 5779 45 Effect effect NN cord-022526-j9kg00qf 5779 46 of of IN cord-022526-j9kg00qf 5779 47 long long JJ cord-022526-j9kg00qf 5779 48 - - HYPH cord-022526-j9kg00qf 5779 49 term term NN cord-022526-j9kg00qf 5779 50 administration administration NN cord-022526-j9kg00qf 5779 51 of of IN cord-022526-j9kg00qf 5779 52 injectable injectable JJ cord-022526-j9kg00qf 5779 53 enrofloxacin enrofloxacin NNS cord-022526-j9kg00qf 5779 54 solution solution NN cord-022526-j9kg00qf 5779 55 on on IN cord-022526-j9kg00qf 5779 56 physical physical JJ cord-022526-j9kg00qf 5779 57 and and CC cord-022526-j9kg00qf 5779 58 musculoskeletal musculoskeletal JJ cord-022526-j9kg00qf 5779 59 variables variable NNS cord-022526-j9kg00qf 5779 60 in in IN cord-022526-j9kg00qf 5779 61 adult adult NN cord-022526-j9kg00qf 5779 62 horses horse NNS cord-022526-j9kg00qf 5779 63 Peritoneal peritoneal JJ cord-022526-j9kg00qf 5779 64 lavage lavage NN cord-022526-j9kg00qf 5779 65 in in IN cord-022526-j9kg00qf 5779 66 the the DT cord-022526-j9kg00qf 5779 67 horse horse NN cord-022526-j9kg00qf 5779 68 Pharmacologic Pharmacologic NNP cord-022526-j9kg00qf 5779 69 principles principle VBZ cord-022526-j9kg00qf 5779 70 Therapeutic therapeutic JJ cord-022526-j9kg00qf 5779 71 drug drug NN cord-022526-j9kg00qf 5779 72 monitoring monitoring NN cord-022526-j9kg00qf 5779 73 : : : cord-022526-j9kg00qf 5779 74 a a DT cord-022526-j9kg00qf 5779 75 tool tool NN cord-022526-j9kg00qf 5779 76 for for IN cord-022526-j9kg00qf 5779 77 rational rational JJ cord-022526-j9kg00qf 5779 78 drug drug NN cord-022526-j9kg00qf 5779 79 therapy therapy NN cord-022526-j9kg00qf 5779 80 . . . cord-022526-j9kg00qf 5780 1 Proceedings proceeding NNS cord-022526-j9kg00qf 5780 2 of of IN cord-022526-j9kg00qf 5780 3 the the DT cord-022526-j9kg00qf 5780 4 seventh seventh JJ cord-022526-j9kg00qf 5780 5 American American NNP cord-022526-j9kg00qf 5780 6 College College NNP cord-022526-j9kg00qf 5780 7 of of IN cord-022526-j9kg00qf 5780 8 Veterinary Veterinary NNP cord-022526-j9kg00qf 5780 9 Internal Internal NNP cord-022526-j9kg00qf 5780 10 Medicine Medicine NNP cord-022526-j9kg00qf 5780 11 Forum Forum NNP cord-022526-j9kg00qf 5780 12 Toxicity toxicity NN cord-022526-j9kg00qf 5780 13 of of IN cord-022526-j9kg00qf 5780 14 quinolones quinolone NNS cord-022526-j9kg00qf 5781 1 Although although IN cord-022526-j9kg00qf 5781 2 a a DT cord-022526-j9kg00qf 5781 3 number number NN cord-022526-j9kg00qf 5781 4 of of IN cord-022526-j9kg00qf 5781 5 potential potential JJ cord-022526-j9kg00qf 5781 6 causes cause NNS cord-022526-j9kg00qf 5781 7 of of IN cord-022526-j9kg00qf 5781 8 peritonitis peritonitis NN cord-022526-j9kg00qf 5781 9 exist exist VBP cord-022526-j9kg00qf 5781 10 , , , cord-022526-j9kg00qf 5781 11 sepsis sepsis NN cord-022526-j9kg00qf 5781 12 is be VBZ cord-022526-j9kg00qf 5781 13 a a DT cord-022526-j9kg00qf 5781 14 common common JJ cord-022526-j9kg00qf 5781 15 and and CC cord-022526-j9kg00qf 5781 16 serious serious JJ cord-022526-j9kg00qf 5781 17 complication complication NN cord-022526-j9kg00qf 5781 18 , , , cord-022526-j9kg00qf 5781 19 and and CC cord-022526-j9kg00qf 5781 20 the the DT cord-022526-j9kg00qf 5781 21 identification identification NN cord-022526-j9kg00qf 5781 22 and and CC cord-022526-j9kg00qf 5781 23 control control NN cord-022526-j9kg00qf 5781 24 of of IN cord-022526-j9kg00qf 5781 25 bacterial bacterial JJ cord-022526-j9kg00qf 5781 26 sepsis sepsis NN cord-022526-j9kg00qf 5781 27 is be VBZ cord-022526-j9kg00qf 5781 28 critical critical JJ cord-022526-j9kg00qf 5781 29 for for IN cord-022526-j9kg00qf 5781 30 a a DT cord-022526-j9kg00qf 5781 31 successful successful JJ cord-022526-j9kg00qf 5781 32 outcome outcome NN cord-022526-j9kg00qf 5781 33 . . . cord-022526-j9kg00qf 5782 1 Bowel bowel NN cord-022526-j9kg00qf 5782 2 leakage leakage NN cord-022526-j9kg00qf 5782 3 ( ( -LRB- cord-022526-j9kg00qf 5782 4 as as RB cord-022526-j9kg00qf 5782 5 well well RB cord-022526-j9kg00qf 5782 6 as as IN cord-022526-j9kg00qf 5782 7 external external JJ cord-022526-j9kg00qf 5782 8 trauma trauma NN cord-022526-j9kg00qf 5782 9 ) ) -RRB- cord-022526-j9kg00qf 5782 10 results result NNS cord-022526-j9kg00qf 5782 11 in in IN cord-022526-j9kg00qf 5782 12 contamination contamination NN cord-022526-j9kg00qf 5782 13 of of IN cord-022526-j9kg00qf 5782 14 the the DT cord-022526-j9kg00qf 5782 15 peritoneum peritoneum NN cord-022526-j9kg00qf 5782 16 with with IN cord-022526-j9kg00qf 5782 17 large large JJ cord-022526-j9kg00qf 5782 18 numbers number NNS cord-022526-j9kg00qf 5782 19 of of IN cord-022526-j9kg00qf 5782 20 many many JJ cord-022526-j9kg00qf 5782 21 types type NNS cord-022526-j9kg00qf 5782 22 of of IN cord-022526-j9kg00qf 5782 23 bacteria bacteria NNS cord-022526-j9kg00qf 5782 24 . . . cord-022526-j9kg00qf 5783 1 The the DT cord-022526-j9kg00qf 5783 2 intestinal intestinal JJ cord-022526-j9kg00qf 5783 3 tract tract NN cord-022526-j9kg00qf 5783 4 contains contain VBZ cord-022526-j9kg00qf 5783 5 a a DT cord-022526-j9kg00qf 5783 6 mixed mixed JJ cord-022526-j9kg00qf 5783 7 population population NN cord-022526-j9kg00qf 5783 8 of of IN cord-022526-j9kg00qf 5783 9 bacteria bacteria NNS cord-022526-j9kg00qf 5783 10 , , , cord-022526-j9kg00qf 5783 11 and and CC cord-022526-j9kg00qf 5783 12 the the DT cord-022526-j9kg00qf 5783 13 quantity quantity NN cord-022526-j9kg00qf 5783 14 of of IN cord-022526-j9kg00qf 5783 15 bacteria bacteria NNS cord-022526-j9kg00qf 5783 16 and and CC cord-022526-j9kg00qf 5783 17 prevalence prevalence NN cord-022526-j9kg00qf 5783 18 of of IN cord-022526-j9kg00qf 5783 19 anaerobic anaerobic JJ cord-022526-j9kg00qf 5783 20 species specie NNS cord-022526-j9kg00qf 5783 21 increase increase VBP cord-022526-j9kg00qf 5783 22 in in IN cord-022526-j9kg00qf 5783 23 the the DT cord-022526-j9kg00qf 5783 24 distal distal JJ cord-022526-j9kg00qf 5783 25 segments segment NNS cord-022526-j9kg00qf 5783 26 . . . cord-022526-j9kg00qf 5784 1 [ [ -LRB- cord-022526-j9kg00qf 5784 2 1 1 CD cord-022526-j9kg00qf 5784 3 ] ] -RRB- cord-022526-j9kg00qf 5784 4 [ [ -LRB- cord-022526-j9kg00qf 5784 5 2 2 CD cord-022526-j9kg00qf 5784 6 ] ] -RRB- cord-022526-j9kg00qf 5784 7 [ [ -LRB- cord-022526-j9kg00qf 5784 8 3 3 CD cord-022526-j9kg00qf 5784 9 ] ] -RRB- cord-022526-j9kg00qf 5784 10 [ [ -LRB- cord-022526-j9kg00qf 5784 11 4 4 CD cord-022526-j9kg00qf 5784 12 ] ] -RRB- cord-022526-j9kg00qf 5784 13 [ [ -LRB- cord-022526-j9kg00qf 5784 14 5 5 CD cord-022526-j9kg00qf 5784 15 ] ] -RRB- cord-022526-j9kg00qf 5784 16 [ [ -LRB- cord-022526-j9kg00qf 5784 17 6 6 CD cord-022526-j9kg00qf 5784 18 ] ] -RRB- cord-022526-j9kg00qf 5784 19 [ [ -LRB- cord-022526-j9kg00qf 5784 20 7 7 CD cord-022526-j9kg00qf 5784 21 ] ] -RRB- cord-022526-j9kg00qf 5785 1 There there EX cord-022526-j9kg00qf 5785 2 are be VBP cord-022526-j9kg00qf 5785 3 approximately approximately RB cord-022526-j9kg00qf 5785 4 1 1 CD cord-022526-j9kg00qf 5785 5 × × NN cord-022526-j9kg00qf 5785 6 10 10 CD cord-022526-j9kg00qf 5785 7 9 9 CD cord-022526-j9kg00qf 5785 8 anaerobic anaerobic JJ cord-022526-j9kg00qf 5785 9 and and CC cord-022526-j9kg00qf 5785 10 1 1 CD cord-022526-j9kg00qf 5785 11 × × NN cord-022526-j9kg00qf 5785 12 10 10 CD cord-022526-j9kg00qf 5785 13 5 5 CD cord-022526-j9kg00qf 5785 14 aerobic aerobic JJ cord-022526-j9kg00qf 5785 15 bacteria bacteria NNS cord-022526-j9kg00qf 5785 16 per per IN cord-022526-j9kg00qf 5785 17 milliliter milliliter NN cord-022526-j9kg00qf 5785 18 of of IN cord-022526-j9kg00qf 5785 19 cecal cecal JJ cord-022526-j9kg00qf 5785 20 and and CC cord-022526-j9kg00qf 5785 21 colonic colonic JJ cord-022526-j9kg00qf 5785 22 fluid fluid NN cord-022526-j9kg00qf 5785 23 , , . cord-022526-j9kg00qf 5786 1 thus thus RB cord-022526-j9kg00qf 5786 2 the the DT cord-022526-j9kg00qf 5786 3 potential potential NN cord-022526-j9kg00qf 5786 4 for for IN cord-022526-j9kg00qf 5786 5 bacterial bacterial JJ cord-022526-j9kg00qf 5786 6 contamination contamination NN cord-022526-j9kg00qf 5786 7 of of IN cord-022526-j9kg00qf 5786 8 the the DT cord-022526-j9kg00qf 5786 9 peritoneum peritoneum NN cord-022526-j9kg00qf 5786 10 is be VBZ cord-022526-j9kg00qf 5786 11 great great JJ cord-022526-j9kg00qf 5786 12 . . . cord-022526-j9kg00qf 5787 1 High high JJ cord-022526-j9kg00qf 5787 2 mortality mortality NN cord-022526-j9kg00qf 5787 3 is be VBZ cord-022526-j9kg00qf 5787 4 associated associate VBN cord-022526-j9kg00qf 5787 5 with with IN cord-022526-j9kg00qf 5787 6 contamination contamination NN cord-022526-j9kg00qf 5787 7 from from IN cord-022526-j9kg00qf 5787 8 the the DT cord-022526-j9kg00qf 5787 9 lower low JJR cord-022526-j9kg00qf 5787 10 bowel bowel NN cord-022526-j9kg00qf 5787 11 because because IN cord-022526-j9kg00qf 5787 12 of of IN cord-022526-j9kg00qf 5787 13 the the DT cord-022526-j9kg00qf 5787 14 large large JJ cord-022526-j9kg00qf 5787 15 numbers number NNS cord-022526-j9kg00qf 5787 16 of of IN cord-022526-j9kg00qf 5787 17 bacteria bacteria NNS cord-022526-j9kg00qf 5787 18 present present JJ cord-022526-j9kg00qf 5787 19 . . . cord-022526-j9kg00qf 5788 1 8 8 CD cord-022526-j9kg00qf 5789 1 Hirsch Hirsch NNP cord-022526-j9kg00qf 5789 2 and and CC cord-022526-j9kg00qf 5789 3 Jang Jang NNP cord-022526-j9kg00qf 5789 4 9 9 CD cord-022526-j9kg00qf 5789 5 reported report VBD cord-022526-j9kg00qf 5789 6 isolation isolation NN cord-022526-j9kg00qf 5789 7 of of IN cord-022526-j9kg00qf 5789 8 an an DT cord-022526-j9kg00qf 5789 9 infective infective JJ cord-022526-j9kg00qf 5789 10 agent agent NN cord-022526-j9kg00qf 5789 11 from from IN cord-022526-j9kg00qf 5789 12 equine equine JJ cord-022526-j9kg00qf 5789 13 peritoneal peritoneal JJ cord-022526-j9kg00qf 5789 14 fluid fluid NN cord-022526-j9kg00qf 5789 15 in in IN cord-022526-j9kg00qf 5789 16 approximately approximately RB cord-022526-j9kg00qf 5789 17 25 25 CD cord-022526-j9kg00qf 5789 18 % % NN cord-022526-j9kg00qf 5789 19 of of IN cord-022526-j9kg00qf 5789 20 attempts attempt NNS cord-022526-j9kg00qf 5789 21 . . . cord-022526-j9kg00qf 5790 1 Obligate obligate VB cord-022526-j9kg00qf 5790 2 anaerobic anaerobic JJ cord-022526-j9kg00qf 5790 3 bacteria bacteria NNS cord-022526-j9kg00qf 5790 4 were be VBD cord-022526-j9kg00qf 5790 5 cultured cultured JJ cord-022526-j9kg00qf 5790 6 most most RBS cord-022526-j9kg00qf 5790 7 frequently frequently RB cord-022526-j9kg00qf 5790 8 , , , cord-022526-j9kg00qf 5790 9 followed follow VBN cord-022526-j9kg00qf 5790 10 by by IN cord-022526-j9kg00qf 5790 11 members member NNS cord-022526-j9kg00qf 5790 12 of of IN cord-022526-j9kg00qf 5790 13 the the DT cord-022526-j9kg00qf 5790 14 Enterobacteriaceae Enterobacteriaceae NNP cord-022526-j9kg00qf 5790 15 family family NN cord-022526-j9kg00qf 5790 16 ( ( -LRB- cord-022526-j9kg00qf 5790 17 Escherichia Escherichia NNP cord-022526-j9kg00qf 5790 18 coli coli NNS cord-022526-j9kg00qf 5790 19 ) ) -RRB- cord-022526-j9kg00qf 5790 20 . . . cord-022526-j9kg00qf 5791 1 Penicillin penicillin NN cord-022526-j9kg00qf 5791 2 - - HYPH cord-022526-j9kg00qf 5791 3 resistant resistant JJ cord-022526-j9kg00qf 5791 4 Bacteroides Bacteroides NNP cord-022526-j9kg00qf 5791 5 fragilis fragili NNS cord-022526-j9kg00qf 5791 6 was be VBD cord-022526-j9kg00qf 5791 7 isolated isolate VBN cord-022526-j9kg00qf 5791 8 from from IN cord-022526-j9kg00qf 5791 9 10 10 CD cord-022526-j9kg00qf 5791 10 % % NN cord-022526-j9kg00qf 5791 11 to to TO cord-022526-j9kg00qf 5791 12 20 20 CD cord-022526-j9kg00qf 5791 13 % % NN cord-022526-j9kg00qf 5791 14 of of IN cord-022526-j9kg00qf 5791 15 cases case NNS cord-022526-j9kg00qf 5791 16 . . . cord-022526-j9kg00qf 5792 1 In in IN cord-022526-j9kg00qf 5792 2 another another DT cord-022526-j9kg00qf 5792 3 study study NN cord-022526-j9kg00qf 5792 4 in in IN cord-022526-j9kg00qf 5792 5 which which WDT cord-022526-j9kg00qf 5792 6 bacteria bacteria NNS cord-022526-j9kg00qf 5792 7 were be VBD cord-022526-j9kg00qf 5792 8 identified identify VBN cord-022526-j9kg00qf 5792 9 in in IN cord-022526-j9kg00qf 5792 10 equine equine JJ cord-022526-j9kg00qf 5792 11 abdominal abdominal JJ cord-022526-j9kg00qf 5792 12 fluid fluid NN cord-022526-j9kg00qf 5792 13 by by IN cord-022526-j9kg00qf 5792 14 cytologic cytologic JJ cord-022526-j9kg00qf 5792 15 examination examination NN cord-022526-j9kg00qf 5792 16 or or CC cord-022526-j9kg00qf 5792 17 culture culture NN cord-022526-j9kg00qf 5792 18 , , , cord-022526-j9kg00qf 5792 19 E. E. NNP cord-022526-j9kg00qf 5792 20 coli coli NNS cord-022526-j9kg00qf 5792 21 was be VBD cord-022526-j9kg00qf 5792 22 the the DT cord-022526-j9kg00qf 5792 23 organism organism NN cord-022526-j9kg00qf 5792 24 most most RBS cord-022526-j9kg00qf 5792 25 commonly commonly RB cord-022526-j9kg00qf 5792 26 isolated isolate VBN cord-022526-j9kg00qf 5792 27 . . . cord-022526-j9kg00qf 5793 1 10 10 CD cord-022526-j9kg00qf 5794 1 In in IN cord-022526-j9kg00qf 5794 2 human human JJ cord-022526-j9kg00qf 5794 3 beings being NNS cord-022526-j9kg00qf 5794 4 and and CC cord-022526-j9kg00qf 5794 5 laboratory laboratory NN cord-022526-j9kg00qf 5794 6 animals animal NNS cord-022526-j9kg00qf 5794 7 the the DT cord-022526-j9kg00qf 5794 8 well well RB cord-022526-j9kg00qf 5794 9 - - HYPH cord-022526-j9kg00qf 5794 10 established establish VBN cord-022526-j9kg00qf 5794 11 fact fact NN cord-022526-j9kg00qf 5794 12 is be VBZ cord-022526-j9kg00qf 5794 13 that that IN cord-022526-j9kg00qf 5794 14 despite despite IN cord-022526-j9kg00qf 5794 15 the the DT cord-022526-j9kg00qf 5794 16 variety variety NN cord-022526-j9kg00qf 5794 17 of of IN cord-022526-j9kg00qf 5794 18 organisms organism NNS cord-022526-j9kg00qf 5794 19 initially initially RB cord-022526-j9kg00qf 5794 20 introduced introduce VBD cord-022526-j9kg00qf 5794 21 subsequent subsequent JJ cord-022526-j9kg00qf 5794 22 to to IN cord-022526-j9kg00qf 5794 23 these these DT cord-022526-j9kg00qf 5794 24 events event NNS cord-022526-j9kg00qf 5794 25 , , , cord-022526-j9kg00qf 5794 26 established establish VBN cord-022526-j9kg00qf 5794 27 infections infection NNS cord-022526-j9kg00qf 5794 28 are be VBP cord-022526-j9kg00qf 5794 29 characterized characterize VBN cord-022526-j9kg00qf 5794 30 by by IN cord-022526-j9kg00qf 5794 31 only only RB cord-022526-j9kg00qf 5794 32 a a DT cord-022526-j9kg00qf 5794 33 few few JJ cord-022526-j9kg00qf 5794 34 types type NNS cord-022526-j9kg00qf 5794 35 of of IN cord-022526-j9kg00qf 5794 36 bacteria bacteria NNS cord-022526-j9kg00qf 5794 37 , , , cord-022526-j9kg00qf 5794 38 which which WDT cord-022526-j9kg00qf 5794 39 are be VBP cord-022526-j9kg00qf 5794 40 often often RB cord-022526-j9kg00qf 5794 41 gram gram JJ cord-022526-j9kg00qf 5794 42 - - HYPH cord-022526-j9kg00qf 5794 43 negative negative JJ cord-022526-j9kg00qf 5794 44 aerobes aerobe NNS cord-022526-j9kg00qf 5794 45 and and CC cord-022526-j9kg00qf 5794 46 anaerobic anaerobic JJ cord-022526-j9kg00qf 5794 47 bacteria bacteria NNS cord-022526-j9kg00qf 5794 48 . . . cord-022526-j9kg00qf 5795 1 2 2 LS cord-022526-j9kg00qf 5796 1 This this DT cord-022526-j9kg00qf 5796 2 selectivity selectivity NN cord-022526-j9kg00qf 5796 3 occurs occur VBZ cord-022526-j9kg00qf 5796 4 through through IN cord-022526-j9kg00qf 5796 5 the the DT cord-022526-j9kg00qf 5796 6 processes process NNS cord-022526-j9kg00qf 5796 7 of of IN cord-022526-j9kg00qf 5796 8 selective selective JJ cord-022526-j9kg00qf 5796 9 reduction reduction NN cord-022526-j9kg00qf 5796 10 of of IN cord-022526-j9kg00qf 5796 11 bacterial bacterial JJ cord-022526-j9kg00qf 5796 12 populations population NNS cord-022526-j9kg00qf 5796 13 and and CC cord-022526-j9kg00qf 5796 14 bacterial bacterial JJ cord-022526-j9kg00qf 5796 15 synergism synergism NN cord-022526-j9kg00qf 5796 16 . . . cord-022526-j9kg00qf 5797 1 A a DT cord-022526-j9kg00qf 5797 2 well well RB cord-022526-j9kg00qf 5797 3 - - HYPH cord-022526-j9kg00qf 5797 4 known know VBN cord-022526-j9kg00qf 5797 5 example example NN cord-022526-j9kg00qf 5797 6 of of IN cord-022526-j9kg00qf 5797 7 synergism synergism NN cord-022526-j9kg00qf 5797 8 in in IN cord-022526-j9kg00qf 5797 9 human human JJ cord-022526-j9kg00qf 5797 10 beings being NNS cord-022526-j9kg00qf 5797 11 and and CC cord-022526-j9kg00qf 5797 12 laboratory laboratory NN cord-022526-j9kg00qf 5797 13 animals animal NNS cord-022526-j9kg00qf 5797 14 is be VBZ cord-022526-j9kg00qf 5797 15 peritonitis peritonitis NN cord-022526-j9kg00qf 5797 16 involving involve VBG cord-022526-j9kg00qf 5797 17 E. E. NNP cord-022526-j9kg00qf 5797 18 coli coli NNS cord-022526-j9kg00qf 5797 19 and and CC cord-022526-j9kg00qf 5797 20 B. B. NNP cord-022526-j9kg00qf 5797 21 fragilus fragilus NNP cord-022526-j9kg00qf 5797 22 . . . cord-022526-j9kg00qf 5798 1 The the DT cord-022526-j9kg00qf 5798 2 presence presence NN cord-022526-j9kg00qf 5798 3 of of IN cord-022526-j9kg00qf 5798 4 each each DT cord-022526-j9kg00qf 5798 5 organism organism NN cord-022526-j9kg00qf 5798 6 is be VBZ cord-022526-j9kg00qf 5798 7 beneficial beneficial JJ cord-022526-j9kg00qf 5798 8 to to IN cord-022526-j9kg00qf 5798 9 the the DT cord-022526-j9kg00qf 5798 10 survival survival NN cord-022526-j9kg00qf 5798 11 of of IN cord-022526-j9kg00qf 5798 12 the the DT cord-022526-j9kg00qf 5798 13 other other JJ cord-022526-j9kg00qf 5798 14 , , , cord-022526-j9kg00qf 5798 15 and and CC cord-022526-j9kg00qf 5798 16 each each DT cord-022526-j9kg00qf 5798 17 is be VBZ cord-022526-j9kg00qf 5798 18 important important JJ cord-022526-j9kg00qf 5798 19 in in IN cord-022526-j9kg00qf 5798 20 the the DT cord-022526-j9kg00qf 5798 21 overall overall JJ cord-022526-j9kg00qf 5798 22 pathogenesis pathogenesis NN cord-022526-j9kg00qf 5798 23 of of IN cord-022526-j9kg00qf 5798 24 the the DT cord-022526-j9kg00qf 5798 25 disease disease NN cord-022526-j9kg00qf 5798 26 . . . cord-022526-j9kg00qf 5799 1 E. E. NNP cord-022526-j9kg00qf 5799 2 coli coli NNS cord-022526-j9kg00qf 5799 3 is be VBZ cord-022526-j9kg00qf 5799 4 associated associate VBN cord-022526-j9kg00qf 5799 5 with with IN cord-022526-j9kg00qf 5799 6 septicemia septicemia NN cord-022526-j9kg00qf 5799 7 and and CC cord-022526-j9kg00qf 5799 8 early early JJ cord-022526-j9kg00qf 5799 9 mortality mortality NN cord-022526-j9kg00qf 5799 10 , , , cord-022526-j9kg00qf 5799 11 whereas whereas IN cord-022526-j9kg00qf 5799 12 B. B. NNP cord-022526-j9kg00qf 5799 13 fragilis fragilis NN cord-022526-j9kg00qf 5799 14 infection infection NN cord-022526-j9kg00qf 5799 15 tends tend VBZ cord-022526-j9kg00qf 5799 16 to to TO cord-022526-j9kg00qf 5799 17 result result VB cord-022526-j9kg00qf 5799 18 in in IN cord-022526-j9kg00qf 5799 19 chronic chronic JJ cord-022526-j9kg00qf 5799 20 abscessation abscessation NN cord-022526-j9kg00qf 5799 21 with with IN cord-022526-j9kg00qf 5799 22 delayed delay VBN cord-022526-j9kg00qf 5799 23 morbidity morbidity NN cord-022526-j9kg00qf 5799 24 and and CC cord-022526-j9kg00qf 5799 25 mortality mortality NN cord-022526-j9kg00qf 5799 26 . . . cord-022526-j9kg00qf 5800 1 Some some DT cord-022526-j9kg00qf 5800 2 evidence evidence NN cord-022526-j9kg00qf 5800 3 suggests suggest VBZ cord-022526-j9kg00qf 5800 4 that that IN cord-022526-j9kg00qf 5800 5 in in IN cord-022526-j9kg00qf 5800 6 horses horse NNS cord-022526-j9kg00qf 5800 7 , , , cord-022526-j9kg00qf 5800 8 in in IN cord-022526-j9kg00qf 5800 9 addition addition NN cord-022526-j9kg00qf 5800 10 to to IN cord-022526-j9kg00qf 5800 11 coliforms coliform NNS cord-022526-j9kg00qf 5800 12 and and CC cord-022526-j9kg00qf 5800 13 anaerobes anaerobe NNS cord-022526-j9kg00qf 5800 14 , , , cord-022526-j9kg00qf 5800 15 streptococci streptococcus NNS cord-022526-j9kg00qf 5800 16 and and CC cord-022526-j9kg00qf 5800 17 perhaps perhaps RB cord-022526-j9kg00qf 5800 18 C. C. NNP cord-022526-j9kg00qf 5800 19 psuedotuberculosis psuedotuberculosis NNP cord-022526-j9kg00qf 5800 20 may may MD cord-022526-j9kg00qf 5800 21 survive survive VB cord-022526-j9kg00qf 5800 22 selective selective JJ cord-022526-j9kg00qf 5800 23 reduction reduction NN cord-022526-j9kg00qf 5800 24 and and CC cord-022526-j9kg00qf 5800 25 participate participate VB cord-022526-j9kg00qf 5800 26 in in IN cord-022526-j9kg00qf 5800 27 synergistic synergistic JJ cord-022526-j9kg00qf 5800 28 infection infection NN cord-022526-j9kg00qf 5800 29 following follow VBG cord-022526-j9kg00qf 5800 30 polymicrobial polymicrobial JJ cord-022526-j9kg00qf 5800 31 contamination contamination NN cord-022526-j9kg00qf 5800 32 . . . cord-022526-j9kg00qf 5801 1 Biologic biologic JJ cord-022526-j9kg00qf 5801 2 events event NNS cord-022526-j9kg00qf 5801 3 resulting result VBG cord-022526-j9kg00qf 5801 4 from from IN cord-022526-j9kg00qf 5801 5 contamination contamination NN cord-022526-j9kg00qf 5801 6 of of IN cord-022526-j9kg00qf 5801 7 the the DT cord-022526-j9kg00qf 5801 8 abdomen abdomen NN cord-022526-j9kg00qf 5801 9 or or CC cord-022526-j9kg00qf 5801 10 injury injury NN cord-022526-j9kg00qf 5801 11 to to IN cord-022526-j9kg00qf 5801 12 the the DT cord-022526-j9kg00qf 5801 13 mesothelial mesothelial JJ cord-022526-j9kg00qf 5801 14 cells cell NNS cord-022526-j9kg00qf 5801 15 have have VBP cord-022526-j9kg00qf 5801 16 been be VBN cord-022526-j9kg00qf 5801 17 described describe VBN cord-022526-j9kg00qf 5801 18 [ [ -LRB- cord-022526-j9kg00qf 5801 19 1 1 CD cord-022526-j9kg00qf 5801 20 ] ] -RRB- cord-022526-j9kg00qf 5802 1 [ [ -LRB- cord-022526-j9kg00qf 5802 2 2 2 LS cord-022526-j9kg00qf 5802 3 ] ] -RRB- cord-022526-j9kg00qf 5802 4 [ [ -LRB- cord-022526-j9kg00qf 5802 5 3 3 CD cord-022526-j9kg00qf 5802 6 ] ] -RRB- cord-022526-j9kg00qf 5802 7 [ [ -LRB- cord-022526-j9kg00qf 5802 8 4 4 CD cord-022526-j9kg00qf 5802 9 ] ] -RRB- cord-022526-j9kg00qf 5802 10 and and CC cord-022526-j9kg00qf 5802 11 include include VBP cord-022526-j9kg00qf 5802 12 release release NN cord-022526-j9kg00qf 5802 13 of of IN cord-022526-j9kg00qf 5802 14 catecholamines catecholamine NNS cord-022526-j9kg00qf 5802 15 , , , cord-022526-j9kg00qf 5802 16 histamine histamine NN cord-022526-j9kg00qf 5802 17 , , , cord-022526-j9kg00qf 5802 18 and and CC cord-022526-j9kg00qf 5802 19 serotonin serotonin NN cord-022526-j9kg00qf 5802 20 from from IN cord-022526-j9kg00qf 5802 21 peritoneal peritoneal JJ cord-022526-j9kg00qf 5802 22 mast mast NN cord-022526-j9kg00qf 5802 23 cells cell NNS cord-022526-j9kg00qf 5802 24 ; ; : cord-022526-j9kg00qf 5802 25 vasodilation vasodilation NN cord-022526-j9kg00qf 5802 26 and and CC cord-022526-j9kg00qf 5802 27 hyperemia hyperemia NN cord-022526-j9kg00qf 5802 28 ; ; : cord-022526-j9kg00qf 5802 29 increase increase NN cord-022526-j9kg00qf 5802 30 in in IN cord-022526-j9kg00qf 5802 31 peritoneal peritoneal JJ cord-022526-j9kg00qf 5802 32 vascular vascular JJ cord-022526-j9kg00qf 5802 33 permeability permeability NN cord-022526-j9kg00qf 5802 34 ; ; : cord-022526-j9kg00qf 5802 35 secretion secretion NN cord-022526-j9kg00qf 5802 36 of of IN cord-022526-j9kg00qf 5802 37 protein protein NN cord-022526-j9kg00qf 5802 38 - - HYPH cord-022526-j9kg00qf 5802 39 rich rich JJ cord-022526-j9kg00qf 5802 40 fluid fluid NN cord-022526-j9kg00qf 5802 41 into into IN cord-022526-j9kg00qf 5802 42 the the DT cord-022526-j9kg00qf 5802 43 peritoneum peritoneum NN cord-022526-j9kg00qf 5802 44 ; ; : cord-022526-j9kg00qf 5802 45 transformation transformation NN cord-022526-j9kg00qf 5802 46 of of IN cord-022526-j9kg00qf 5802 47 mesothelial mesothelial JJ cord-022526-j9kg00qf 5802 48 cells cell NNS cord-022526-j9kg00qf 5802 49 into into IN cord-022526-j9kg00qf 5802 50 macrophages macrophage NNS cord-022526-j9kg00qf 5802 51 ; ; : cord-022526-j9kg00qf 5802 52 and and CC cord-022526-j9kg00qf 5802 53 influx influx NN cord-022526-j9kg00qf 5802 54 of of IN cord-022526-j9kg00qf 5802 55 polymorphonuclear polymorphonuclear JJ cord-022526-j9kg00qf 5802 56 cells cell NNS cord-022526-j9kg00qf 5802 57 , , , cord-022526-j9kg00qf 5802 58 humoral humoral JJ cord-022526-j9kg00qf 5802 59 opsonins opsonin NNS cord-022526-j9kg00qf 5802 60 , , , cord-022526-j9kg00qf 5802 61 natural natural JJ cord-022526-j9kg00qf 5802 62 antibodies antibody NNS cord-022526-j9kg00qf 5802 63 , , , cord-022526-j9kg00qf 5802 64 and and CC cord-022526-j9kg00qf 5802 65 serum serum NN cord-022526-j9kg00qf 5802 66 complement complement NN cord-022526-j9kg00qf 5802 67 into into IN cord-022526-j9kg00qf 5802 68 the the DT cord-022526-j9kg00qf 5802 69 peritoneal peritoneal JJ cord-022526-j9kg00qf 5802 70 cavity cavity NN cord-022526-j9kg00qf 5802 71 . . . cord-022526-j9kg00qf 5803 1 Additionally additionally RB cord-022526-j9kg00qf 5803 2 , , , cord-022526-j9kg00qf 5803 3 depression depression NN cord-022526-j9kg00qf 5803 4 of of IN cord-022526-j9kg00qf 5803 5 the the DT cord-022526-j9kg00qf 5803 6 peritoneal peritoneal JJ cord-022526-j9kg00qf 5803 7 fibrinolytic fibrinolytic JJ cord-022526-j9kg00qf 5803 8 activity activity NN cord-022526-j9kg00qf 5803 9 , , , cord-022526-j9kg00qf 5803 10 fibrin fibrin NN cord-022526-j9kg00qf 5803 11 deposits deposit NNS cord-022526-j9kg00qf 5803 12 on on IN cord-022526-j9kg00qf 5803 13 the the DT cord-022526-j9kg00qf 5803 14 peritoneal peritoneal NN cord-022526-j9kg00qf 5803 15 surface surface NN cord-022526-j9kg00qf 5803 16 , , , cord-022526-j9kg00qf 5803 17 and and CC cord-022526-j9kg00qf 5803 18 sympathetic sympathetic JJ cord-022526-j9kg00qf 5803 19 - - HYPH cord-022526-j9kg00qf 5803 20 mediated mediate VBN cord-022526-j9kg00qf 5803 21 ileus ileus NN cord-022526-j9kg00qf 5803 22 of of IN cord-022526-j9kg00qf 5803 23 the the DT cord-022526-j9kg00qf 5803 24 gastrointestinal gastrointestinal JJ cord-022526-j9kg00qf 5803 25 tract tract NN cord-022526-j9kg00qf 5803 26 can can MD cord-022526-j9kg00qf 5803 27 occur occur VB cord-022526-j9kg00qf 5803 28 . . . cord-022526-j9kg00qf 5804 1 These these DT cord-022526-j9kg00qf 5804 2 processes process NNS cord-022526-j9kg00qf 5804 3 benefit benefit VBP cord-022526-j9kg00qf 5804 4 the the DT cord-022526-j9kg00qf 5804 5 animal animal NN cord-022526-j9kg00qf 5804 6 by by IN cord-022526-j9kg00qf 5804 7 confining confine VBG cord-022526-j9kg00qf 5804 8 contamination contamination NN cord-022526-j9kg00qf 5804 9 and and CC cord-022526-j9kg00qf 5804 10 infection infection NN cord-022526-j9kg00qf 5804 11 , , , cord-022526-j9kg00qf 5804 12 and and CC cord-022526-j9kg00qf 5804 13 indeed indeed RB cord-022526-j9kg00qf 5804 14 , , , cord-022526-j9kg00qf 5804 15 with with IN cord-022526-j9kg00qf 5804 16 clean clean JJ cord-022526-j9kg00qf 5804 17 , , , cord-022526-j9kg00qf 5804 18 minimally minimally RB cord-022526-j9kg00qf 5804 19 invasive invasive JJ cord-022526-j9kg00qf 5804 20 procedures procedure NNS cord-022526-j9kg00qf 5804 21 such such JJ cord-022526-j9kg00qf 5804 22 as as IN cord-022526-j9kg00qf 5804 23 enterocentesis enterocentesis NN cord-022526-j9kg00qf 5804 24 or or CC cord-022526-j9kg00qf 5804 25 trocharization trocharization NN cord-022526-j9kg00qf 5804 26 , , , cord-022526-j9kg00qf 5804 27 this this DT cord-022526-j9kg00qf 5804 28 is be VBZ cord-022526-j9kg00qf 5804 29 effective effective JJ cord-022526-j9kg00qf 5804 30 . . . cord-022526-j9kg00qf 5805 1 However however RB cord-022526-j9kg00qf 5805 2 , , , cord-022526-j9kg00qf 5805 3 with with IN cord-022526-j9kg00qf 5805 4 greater great JJR cord-022526-j9kg00qf 5805 5 severity severity NN cord-022526-j9kg00qf 5805 6 of of IN cord-022526-j9kg00qf 5805 7 peritoneal peritoneal JJ cord-022526-j9kg00qf 5805 8 contamination contamination NN cord-022526-j9kg00qf 5805 9 or or CC cord-022526-j9kg00qf 5805 10 irritation irritation NN cord-022526-j9kg00qf 5805 11 , , , cord-022526-j9kg00qf 5805 12 these these DT cord-022526-j9kg00qf 5805 13 processes process NNS cord-022526-j9kg00qf 5805 14 are be VBP cord-022526-j9kg00qf 5805 15 magnified magnify VBN cord-022526-j9kg00qf 5805 16 and and CC cord-022526-j9kg00qf 5805 17 become become VBP cord-022526-j9kg00qf 5805 18 deleterious deleterious JJ cord-022526-j9kg00qf 5805 19 , , , cord-022526-j9kg00qf 5805 20 resulting result VBG cord-022526-j9kg00qf 5805 21 in in IN cord-022526-j9kg00qf 5805 22 problems problem NNS cord-022526-j9kg00qf 5805 23 such such JJ cord-022526-j9kg00qf 5805 24 as as IN cord-022526-j9kg00qf 5805 25 hypovolemia hypovolemia NN cord-022526-j9kg00qf 5805 26 , , , cord-022526-j9kg00qf 5805 27 hypoproteinemia hypoproteinemia NNP cord-022526-j9kg00qf 5805 28 , , , cord-022526-j9kg00qf 5805 29 ileus ileus NN cord-022526-j9kg00qf 5805 30 with with IN cord-022526-j9kg00qf 5805 31 resultant resultant JJ cord-022526-j9kg00qf 5805 32 bowel bowel NN cord-022526-j9kg00qf 5805 33 distention distention NN cord-022526-j9kg00qf 5805 34 , , , cord-022526-j9kg00qf 5805 35 ischemia ischemia NN cord-022526-j9kg00qf 5805 36 of of IN cord-022526-j9kg00qf 5805 37 the the DT cord-022526-j9kg00qf 5805 38 bowel bowel NN cord-022526-j9kg00qf 5805 39 wall wall NN cord-022526-j9kg00qf 5805 40 with with IN cord-022526-j9kg00qf 5805 41 subsequent subsequent JJ cord-022526-j9kg00qf 5805 42 absorption absorption NN cord-022526-j9kg00qf 5805 43 of of IN cord-022526-j9kg00qf 5805 44 bacteria bacteria NNS cord-022526-j9kg00qf 5805 45 and and CC cord-022526-j9kg00qf 5805 46 toxins toxin NNS cord-022526-j9kg00qf 5805 47 , , , cord-022526-j9kg00qf 5805 48 and and CC cord-022526-j9kg00qf 5805 49 ultimately ultimately RB cord-022526-j9kg00qf 5805 50 adhesion adhesion NN cord-022526-j9kg00qf 5805 51 and and CC cord-022526-j9kg00qf 5805 52 abscess abscess NN cord-022526-j9kg00qf 5805 53 formation formation NN cord-022526-j9kg00qf 5805 54 . . . cord-022526-j9kg00qf 5806 1 Additionally additionally RB cord-022526-j9kg00qf 5806 2 , , , cord-022526-j9kg00qf 5806 3 systemic systemic JJ cord-022526-j9kg00qf 5806 4 responses response NNS cord-022526-j9kg00qf 5806 5 to to IN cord-022526-j9kg00qf 5806 6 bacterial bacterial JJ cord-022526-j9kg00qf 5806 7 toxins toxin NNS cord-022526-j9kg00qf 5806 8 , , , cord-022526-j9kg00qf 5806 9 particularly particularly RB cord-022526-j9kg00qf 5806 10 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 5806 11 , , , cord-022526-j9kg00qf 5806 12 11 11 CD cord-022526-j9kg00qf 5806 13 , , , cord-022526-j9kg00qf 5806 14 12 12 CD cord-022526-j9kg00qf 5806 15 can can MD cord-022526-j9kg00qf 5806 16 compromise compromise VB cord-022526-j9kg00qf 5806 17 the the DT cord-022526-j9kg00qf 5806 18 metabolic metabolic JJ cord-022526-j9kg00qf 5806 19 condition condition NN cord-022526-j9kg00qf 5806 20 of of IN cord-022526-j9kg00qf 5806 21 the the DT cord-022526-j9kg00qf 5806 22 patient patient NN cord-022526-j9kg00qf 5806 23 further further RB cord-022526-j9kg00qf 5806 24 . . . cord-022526-j9kg00qf 5807 1 Equine equine JJ cord-022526-j9kg00qf 5807 2 peritoneal peritoneal JJ cord-022526-j9kg00qf 5807 3 macrophages macrophage NNS cord-022526-j9kg00qf 5807 4 release release VBP cord-022526-j9kg00qf 5807 5 several several JJ cord-022526-j9kg00qf 5807 6 mediators mediator NNS cord-022526-j9kg00qf 5807 7 when when WRB cord-022526-j9kg00qf 5807 8 exposed expose VBN cord-022526-j9kg00qf 5807 9 to to IN cord-022526-j9kg00qf 5807 10 bacterial bacterial JJ cord-022526-j9kg00qf 5807 11 lipopolysaccharide lipopolysaccharide NN cord-022526-j9kg00qf 5807 12 , , , cord-022526-j9kg00qf 5807 13 13 13 CD cord-022526-j9kg00qf 5807 14 undoubtedly undoubtedly RB cord-022526-j9kg00qf 5807 15 an an DT cord-022526-j9kg00qf 5807 16 important important JJ cord-022526-j9kg00qf 5807 17 component component NN cord-022526-j9kg00qf 5807 18 of of IN cord-022526-j9kg00qf 5807 19 septic septic JJ cord-022526-j9kg00qf 5807 20 peritonitis peritonitis NN cord-022526-j9kg00qf 5807 21 . . . cord-022526-j9kg00qf 5808 1 Pathologic pathologic JJ cord-022526-j9kg00qf 5808 2 description description NN cord-022526-j9kg00qf 5808 3 of of IN cord-022526-j9kg00qf 5808 4 peritonitis peritonitis NN cord-022526-j9kg00qf 5808 5 includes include VBZ cord-022526-j9kg00qf 5808 6 origin origin NN cord-022526-j9kg00qf 5808 7 ( ( -LRB- cord-022526-j9kg00qf 5808 8 primary primary JJ cord-022526-j9kg00qf 5808 9 or or CC cord-022526-j9kg00qf 5808 10 secondary secondary JJ cord-022526-j9kg00qf 5808 11 ) ) -RRB- cord-022526-j9kg00qf 5808 12 , , , cord-022526-j9kg00qf 5808 13 onset onset NN cord-022526-j9kg00qf 5808 14 ( ( -LRB- cord-022526-j9kg00qf 5808 15 peracute peracute NNP cord-022526-j9kg00qf 5808 16 , , , cord-022526-j9kg00qf 5808 17 acute acute JJ cord-022526-j9kg00qf 5808 18 , , , cord-022526-j9kg00qf 5808 19 chronic chronic JJ cord-022526-j9kg00qf 5808 20 ) ) -RRB- cord-022526-j9kg00qf 5808 21 , , , cord-022526-j9kg00qf 5808 22 distribution distribution NN cord-022526-j9kg00qf 5808 23 ( ( -LRB- cord-022526-j9kg00qf 5808 24 localized localize VBN cord-022526-j9kg00qf 5808 25 versus versus IN cord-022526-j9kg00qf 5808 26 diffuse diffuse NN cord-022526-j9kg00qf 5808 27 ) ) -RRB- cord-022526-j9kg00qf 5808 28 , , , cord-022526-j9kg00qf 5808 29 and and CC cord-022526-j9kg00qf 5808 30 presence presence NN cord-022526-j9kg00qf 5808 31 of of IN cord-022526-j9kg00qf 5808 32 bacteria bacteria NNS cord-022526-j9kg00qf 5808 33 ( ( -LRB- cord-022526-j9kg00qf 5808 34 septic septic JJ cord-022526-j9kg00qf 5808 35 versus versus IN cord-022526-j9kg00qf 5808 36 nonseptic nonseptic NNP cord-022526-j9kg00qf 5808 37 ) ) -RRB- cord-022526-j9kg00qf 5808 38 . . . cord-022526-j9kg00qf 5809 1 3 3 LS cord-022526-j9kg00qf 5809 2 , , , cord-022526-j9kg00qf 5809 3 4 4 CD cord-022526-j9kg00qf 5809 4 Clinically clinically RB cord-022526-j9kg00qf 5809 5 , , , cord-022526-j9kg00qf 5809 6 viewing view VBG