id	sid	tid	token	lemma	pos
cord-023443-pvz7dll9	1	1	key	key	JJ
cord-023443-pvz7dll9	1	2	:	:	:
cord-023443-pvz7dll9	1	3	cord-023443-pvz7dll9	cord-023443-pvz7dll9	NN
cord-023443-pvz7dll9	1	4	authors	author	NNS
cord-023443-pvz7dll9	1	5	:	:	:
cord-023443-pvz7dll9	2	1	nan	nan	NNP
cord-023443-pvz7dll9	2	2	title	title	NN
cord-023443-pvz7dll9	2	3	:	:	:
cord-023443-pvz7dll9	2	4	Abstracts	abstract	NNS
cord-023443-pvz7dll9	2	5	for	for	IN
cord-023443-pvz7dll9	2	6	the	the	DT
cord-023443-pvz7dll9	2	7	Scandinavian	Scandinavian	NNP
cord-023443-pvz7dll9	2	8	Society	Society	NNP
cord-023443-pvz7dll9	2	9	for	for	IN
cord-023443-pvz7dll9	2	10	Immunology	Immunology	NNP
cord-023443-pvz7dll9	2	11	35th	35th	JJ
cord-023443-pvz7dll9	3	1	Annual	Annual	NNP
cord-023443-pvz7dll9	3	2	Meeting	Meeting	NNP
cord-023443-pvz7dll9	3	3	and	and	CC
cord-023443-pvz7dll9	3	4	20th	20th	JJ
cord-023443-pvz7dll9	3	5	Summer	Summer	NNP
cord-023443-pvz7dll9	3	6	School	School	NNP
cord-023443-pvz7dll9	3	7	date	date	NN
cord-023443-pvz7dll9	4	1	:	:	:
cord-023443-pvz7dll9	4	2	2004	2004	CD
cord-023443-pvz7dll9	4	3	-	-	HYPH
cord-023443-pvz7dll9	4	4	06	06	CD
cord-023443-pvz7dll9	4	5	-	-	SYM
cord-023443-pvz7dll9	4	6	02	02	CD
cord-023443-pvz7dll9	4	7	journal	journal	NN
cord-023443-pvz7dll9	4	8	:	:	:
cord-023443-pvz7dll9	5	1	Scand	Scand	NNP
cord-023443-pvz7dll9	5	2	J	J	NNP
cord-023443-pvz7dll9	5	3	Immunol	Immunol	NNP
cord-023443-pvz7dll9	5	4	DOI	DOI	NNP
cord-023443-pvz7dll9	5	5	:	:	:
cord-023443-pvz7dll9	6	1	10.1111	10.1111	CD
cord-023443-pvz7dll9	6	2	/	/	SYM
cord-023443-pvz7dll9	6	3	j.1365	j.1365	NN
cord-023443-pvz7dll9	6	4	-	-	HYPH
cord-023443-pvz7dll9	6	5	3083.2004.01423.x	3083.2004.01423.x	NN
cord-023443-pvz7dll9	6	6	sha	sha	NN
cord-023443-pvz7dll9	6	7	:	:	:
cord-023443-pvz7dll9	6	8	fa57f46c72bfecf2df6b9115b4a10e1dc982d8e0	fa57f46c72bfecf2df6b9115b4a10e1dc982d8e0	NNP
cord-023443-pvz7dll9	6	9	doc_id	doc_id	CD
cord-023443-pvz7dll9	6	10	:	:	:
cord-023443-pvz7dll9	6	11	23443	23443	CD
cord-023443-pvz7dll9	6	12	cord_uid	cord_uid	NNS
cord-023443-pvz7dll9	6	13	:	:	:
cord-023443-pvz7dll9	7	1	pvz7dll9	pvz7dll9	NNP
cord-023443-pvz7dll9	8	1	nan	nan	NNP
cord-023443-pvz7dll9	9	1	The	the	DT
cord-023443-pvz7dll9	9	2	nuclear	nuclear	JJ
cord-023443-pvz7dll9	9	3	receptor	receptor	NN
cord-023443-pvz7dll9	9	4	heterodimers	heterodimer	NNS
cord-023443-pvz7dll9	9	5	of	of	IN
cord-023443-pvz7dll9	9	6	liver	liver	NN
cord-023443-pvz7dll9	9	7	X	x	NN
cord-023443-pvz7dll9	9	8	receptors	receptor	NNS
cord-023443-pvz7dll9	9	9	(	(	-LRB-
cord-023443-pvz7dll9	9	10	LXRs	LXRs	NNP
cord-023443-pvz7dll9	9	11	)	)	-RRB-
cord-023443-pvz7dll9	9	12	are	be	VBP
cord-023443-pvz7dll9	9	13	recently	recently	RB
cord-023443-pvz7dll9	9	14	identified	identify	VBN
cord-023443-pvz7dll9	9	15	as	as	IN
cord-023443-pvz7dll9	9	16	key	key	JJ
cord-023443-pvz7dll9	9	17	transcriptional	transcriptional	JJ
cord-023443-pvz7dll9	9	18	regulators	regulator	NNS
cord-023443-pvz7dll9	9	19	of	of	IN
cord-023443-pvz7dll9	9	20	genes	gene	NNS
cord-023443-pvz7dll9	9	21	involved	involve	VBN
cord-023443-pvz7dll9	9	22	in	in	IN
cord-023443-pvz7dll9	9	23	lipid	lipid	NN
cord-023443-pvz7dll9	9	24	homeostasis	homeostasis	NN
cord-023443-pvz7dll9	9	25	and	and	CC
cord-023443-pvz7dll9	9	26	inflammation	inflammation	NN
cord-023443-pvz7dll9	9	27	.	.	.
cord-023443-pvz7dll9	10	1	LXRs	LXRs	NNP
cord-023443-pvz7dll9	10	2	and	and	CC
cord-023443-pvz7dll9	10	3	their	-PRON-	PRP$
cord-023443-pvz7dll9	10	4	ligands	ligand	NNS
cord-023443-pvz7dll9	10	5	are	be	VBP
cord-023443-pvz7dll9	10	6	negative	negative	JJ
cord-023443-pvz7dll9	10	7	regulators	regulator	NNS
cord-023443-pvz7dll9	10	8	of	of	IN
cord-023443-pvz7dll9	10	9	macrophage	macrophage	NN
cord-023443-pvz7dll9	10	10	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	10	11	gene	gene	NN
cord-023443-pvz7dll9	10	12	expression	expression	NN
cord-023443-pvz7dll9	10	13	.	.	.
cord-023443-pvz7dll9	11	1	Multiple	multiple	JJ
cord-023443-pvz7dll9	11	2	sclerosis	sclerosis	NN
cord-023443-pvz7dll9	11	3	(	(	-LRB-
cord-023443-pvz7dll9	11	4	MS	MS	NNP
cord-023443-pvz7dll9	11	5	)	)	-RRB-
cord-023443-pvz7dll9	11	6	,	,	,
cord-023443-pvz7dll9	11	7	a	a	DT
cord-023443-pvz7dll9	11	8	demyelinating	demyelinating	JJ
cord-023443-pvz7dll9	11	9	disease	disease	NN
cord-023443-pvz7dll9	11	10	of	of	IN
cord-023443-pvz7dll9	11	11	the	the	DT
cord-023443-pvz7dll9	11	12	central	central	JJ
cord-023443-pvz7dll9	11	13	nervous	nervous	JJ
cord-023443-pvz7dll9	11	14	system	system	NN
cord-023443-pvz7dll9	11	15	of	of	IN
cord-023443-pvz7dll9	11	16	unknown	unknown	JJ
cord-023443-pvz7dll9	11	17	cause	cause	NN
cord-023443-pvz7dll9	11	18	,	,	,
cord-023443-pvz7dll9	11	19	is	be	VBZ
cord-023443-pvz7dll9	11	20	characterized	characterize	VBN
cord-023443-pvz7dll9	11	21	by	by	IN
cord-023443-pvz7dll9	11	22	recurrent	recurrent	JJ
cord-023443-pvz7dll9	11	23	inflammation	inflammation	NN
cord-023443-pvz7dll9	11	24	involving	involve	VBG
cord-023443-pvz7dll9	11	25	macrophages	macrophage	NNS
cord-023443-pvz7dll9	11	26	and	and	CC
cord-023443-pvz7dll9	11	27	their	-PRON-	PRP$
cord-023443-pvz7dll9	11	28	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	11	29	mediators	mediator	NNS
cord-023443-pvz7dll9	11	30	.	.	.
cord-023443-pvz7dll9	12	1	Sweden	Sweden	NNP
cord-023443-pvz7dll9	12	2	belongs	belong	VBZ
cord-023443-pvz7dll9	12	3	to	to	IN
cord-023443-pvz7dll9	12	4	the	the	DT
cord-023443-pvz7dll9	12	5	countries	country	NNS
cord-023443-pvz7dll9	12	6	with	with	IN
cord-023443-pvz7dll9	12	7	a	a	DT
cord-023443-pvz7dll9	12	8	high	high	JJ
cord-023443-pvz7dll9	12	9	MS	MS	NNP
cord-023443-pvz7dll9	12	10	incidence	incidence	NN
cord-023443-pvz7dll9	12	11	.	.	.
cord-023443-pvz7dll9	13	1	In	in	IN
cord-023443-pvz7dll9	13	2	Italy	Italy	NNP
cord-023443-pvz7dll9	13	3	,	,	,
cord-023443-pvz7dll9	13	4	incidence	incidence	NN
cord-023443-pvz7dll9	13	5	is	be	VBZ
cord-023443-pvz7dll9	13	6	lower	low	JJR
cord-023443-pvz7dll9	13	7	,	,	,
cord-023443-pvz7dll9	13	8	with	with	IN
cord-023443-pvz7dll9	13	9	an	an	DT
cord-023443-pvz7dll9	13	10	exception	exception	NN
cord-023443-pvz7dll9	13	11	for	for	IN
cord-023443-pvz7dll9	13	12	Sardinia	Sardinia	NNP
cord-023443-pvz7dll9	13	13	where	where	WRB
cord-023443-pvz7dll9	13	14	the	the	DT
cord-023443-pvz7dll9	13	15	incidence	incidence	NN
cord-023443-pvz7dll9	13	16	is	be	VBZ
cord-023443-pvz7dll9	13	17	even	even	RB
cord-023443-pvz7dll9	13	18	higher	high	JJR
cord-023443-pvz7dll9	13	19	than	than	IN
cord-023443-pvz7dll9	13	20	that	that	DT
cord-023443-pvz7dll9	13	21	in	in	IN
cord-023443-pvz7dll9	13	22	Sweden	Sweden	NNP
cord-023443-pvz7dll9	13	23	.	.	.
cord-023443-pvz7dll9	14	1	Subjects	subject	NNS
cord-023443-pvz7dll9	14	2	from	from	IN
cord-023443-pvz7dll9	14	3	Sardinia	Sardinia	NNP
cord-023443-pvz7dll9	14	4	are	be	VBP
cord-023443-pvz7dll9	14	5	ethnically	ethnically	RB
cord-023443-pvz7dll9	14	6	more	more	RBR
cord-023443-pvz7dll9	14	7	homogeneous	homogeneous	JJ
cord-023443-pvz7dll9	14	8	and	and	CC
cord-023443-pvz7dll9	14	9	differ	differ	VBP
cord-023443-pvz7dll9	14	10	from	from	IN
cord-023443-pvz7dll9	14	11	Swedes	Swedes	NNPS
cord-023443-pvz7dll9	14	12	,	,	,
cord-023443-pvz7dll9	14	13	also	also	RB
cord-023443-pvz7dll9	14	14	regarding	regard	VBG
cord-023443-pvz7dll9	14	15	genetic	genetic	JJ
cord-023443-pvz7dll9	14	16	background	background	NN
cord-023443-pvz7dll9	14	17	and	and	CC
cord-023443-pvz7dll9	14	18	environment	environment	NN
cord-023443-pvz7dll9	14	19	.	.	.
cord-023443-pvz7dll9	15	1	We	-PRON-	PRP
cord-023443-pvz7dll9	15	2	studied	study	VBD
cord-023443-pvz7dll9	15	3	LXRs	lxr	NNS
cord-023443-pvz7dll9	15	4	and	and	CC
cord-023443-pvz7dll9	15	5	their	-PRON-	PRP$
cord-023443-pvz7dll9	15	6	related	related	JJ
cord-023443-pvz7dll9	15	7	molecules	molecule	NNS
cord-023443-pvz7dll9	15	8	of	of	IN
cord-023443-pvz7dll9	15	9	blood	blood	NN
cord-023443-pvz7dll9	15	10	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	15	11	cells	cell	NNS
cord-023443-pvz7dll9	15	12	(	(	-LRB-
cord-023443-pvz7dll9	15	13	MNCs	mnc	NNS
cord-023443-pvz7dll9	15	14	)	)	-RRB-
cord-023443-pvz7dll9	15	15	from	from	IN
cord-023443-pvz7dll9	15	16	female	female	JJ
cord-023443-pvz7dll9	15	17	patients	patient	NNS
cord-023443-pvz7dll9	15	18	with	with	IN
cord-023443-pvz7dll9	15	19	untreated	untreated	JJ
cord-023443-pvz7dll9	15	20	relapsing	relapse	VBG
cord-023443-pvz7dll9	15	21	-	-	HYPH
cord-023443-pvz7dll9	15	22	remitting	remit	VBG
cord-023443-pvz7dll9	15	23	MS	MS	NNP
cord-023443-pvz7dll9	15	24	from	from	IN
cord-023443-pvz7dll9	15	25	Sassari	Sassari	NNP
cord-023443-pvz7dll9	15	26	,	,	,
cord-023443-pvz7dll9	15	27	Sardinia	Sardinia	NNP
cord-023443-pvz7dll9	15	28	and	and	CC
cord-023443-pvz7dll9	15	29	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	15	30	,	,	,
cord-023443-pvz7dll9	15	31	Sweden	Sweden	NNP
cord-023443-pvz7dll9	15	32	.	.	.
cord-023443-pvz7dll9	16	1	Sex	sex	NN
cord-023443-pvz7dll9	16	2	-	-	HYPH
cord-023443-pvz7dll9	16	3	and	and	CC
cord-023443-pvz7dll9	16	4	age	age	NN
cord-023443-pvz7dll9	16	5	-	-	HYPH
cord-023443-pvz7dll9	16	6	matched	match	VBN
cord-023443-pvz7dll9	16	7	healthy	healthy	JJ
cord-023443-pvz7dll9	16	8	controls	control	NNS
cord-023443-pvz7dll9	16	9	(	(	-LRB-
cord-023443-pvz7dll9	16	10	HCs	HCs	NNP
cord-023443-pvz7dll9	16	11	)	)	-RRB-
cord-023443-pvz7dll9	16	12	were	be	VBD
cord-023443-pvz7dll9	16	13	from	from	IN
cord-023443-pvz7dll9	16	14	both	both	DT
cord-023443-pvz7dll9	16	15	areas	area	NNS
cord-023443-pvz7dll9	16	16	.	.	.
cord-023443-pvz7dll9	17	1	mRNA	mRNA	NNP
cord-023443-pvz7dll9	17	2	expression	expression	NN
cord-023443-pvz7dll9	17	3	was	be	VBD
cord-023443-pvz7dll9	17	4	evaluated	evaluate	VBN
cord-023443-pvz7dll9	17	5	by	by	IN
cord-023443-pvz7dll9	17	6	real	real	JJ
cord-023443-pvz7dll9	17	7	-	-	HYPH
cord-023443-pvz7dll9	17	8	time	time	NN
cord-023443-pvz7dll9	17	9	PCR	PCR	NNP
cord-023443-pvz7dll9	17	10	.	.	.
cord-023443-pvz7dll9	18	1	LXR	LXR	NNP
cord-023443-pvz7dll9	18	2	-	-	:
cord-023443-pvz7dll9	18	3	a	a	NNP
cord-023443-pvz7dll9	18	4	was	be	VBD
cord-023443-pvz7dll9	18	5	lower	low	JJR
cord-023443-pvz7dll9	19	1	(	(	-LRB-
cord-023443-pvz7dll9	19	2	P	p	NN
cord-023443-pvz7dll9	19	3	<	<	XX
cord-023443-pvz7dll9	19	4	0.05	0.05	CD
cord-023443-pvz7dll9	19	5	)	)	-RRB-
cord-023443-pvz7dll9	19	6	in	in	IN
cord-023443-pvz7dll9	19	7	MS	MS	NNP
cord-023443-pvz7dll9	20	1	(	(	-LRB-
cord-023443-pvz7dll9	20	2	mean	mean	VB
cord-023443-pvz7dll9	20	3	AE	AE	NNP
cord-023443-pvz7dll9	20	4	SEM	SEM	NNP
cord-023443-pvz7dll9	20	5	:	:	:
cord-023443-pvz7dll9	20	6	3.1	3.1	CD
cord-023443-pvz7dll9	20	7	AE	AE	NNP
cord-023443-pvz7dll9	20	8	0.2	0.2	CD
cord-023443-pvz7dll9	20	9	;	;	:
cord-023443-pvz7dll9	21	1	n	n	NNP
cord-023443-pvz7dll9	21	2	¼	¼	NNP
cord-023443-pvz7dll9	21	3	37	37	CD
cord-023443-pvz7dll9	21	4	)	)	-RRB-
cord-023443-pvz7dll9	21	5	compared	compare	VBN
cord-023443-pvz7dll9	21	6	to	to	IN
cord-023443-pvz7dll9	21	7	HC	HC	NNP
cord-023443-pvz7dll9	21	8	(	(	-LRB-
cord-023443-pvz7dll9	21	9	3.6	3.6	CD
cord-023443-pvz7dll9	21	10	AE	AE	NNP
cord-023443-pvz7dll9	21	11	0.1	0.1	CD
cord-023443-pvz7dll9	21	12	;	;	:
cord-023443-pvz7dll9	21	13	n	n	NN
cord-023443-pvz7dll9	21	14	¼	¼	NNP
cord-023443-pvz7dll9	21	15	37	37	CD
cord-023443-pvz7dll9	21	16	)	)	-RRB-
cord-023443-pvz7dll9	21	17	.	.	.
cord-023443-pvz7dll9	22	1	LXR	LXR	NNP
cord-023443-pvz7dll9	22	2	-	-	:
cord-023443-pvz7dll9	22	3	a	a	NNP
cord-023443-pvz7dll9	22	4	was	be	VBD
cord-023443-pvz7dll9	22	5	lower	low	JJR
cord-023443-pvz7dll9	22	6	in	in	IN
cord-023443-pvz7dll9	22	7	MS	MS	NNP
cord-023443-pvz7dll9	22	8	from	from	IN
cord-023443-pvz7dll9	22	9	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	22	10	(	(	-LRB-
cord-023443-pvz7dll9	22	11	2.6	2.6	CD
cord-023443-pvz7dll9	22	12	AE	AE	NNP
cord-023443-pvz7dll9	22	13	0.2	0.2	CD
cord-023443-pvz7dll9	22	14	;	;	:
cord-023443-pvz7dll9	22	15	n	n	NN
cord-023443-pvz7dll9	22	16	¼	¼	NNP
cord-023443-pvz7dll9	22	17	22	22	CD
cord-023443-pvz7dll9	22	18	)	)	-RRB-
cord-023443-pvz7dll9	22	19	compared	compare	VBN
cord-023443-pvz7dll9	22	20	to	to	IN
cord-023443-pvz7dll9	22	21	corresponding	correspond	VBG
cord-023443-pvz7dll9	22	22	HC	HC	NNP
cord-023443-pvz7dll9	22	23	(	(	-LRB-
cord-023443-pvz7dll9	22	24	3.4	3.4	CD
cord-023443-pvz7dll9	22	25	AE	AE	NNP
cord-023443-pvz7dll9	22	26	0.1	0.1	CD
cord-023443-pvz7dll9	22	27	;	;	:
cord-023443-pvz7dll9	22	28	n	n	NN
cord-023443-pvz7dll9	22	29	¼	¼	NNP
cord-023443-pvz7dll9	22	30	22	22	CD
cord-023443-pvz7dll9	22	31	;	;	:
cord-023443-pvz7dll9	22	32	P	p	NN
cord-023443-pvz7dll9	22	33	<	<	XX
cord-023443-pvz7dll9	22	34	0.01	0.01	CD
cord-023443-pvz7dll9	22	35	)	)	-RRB-
cord-023443-pvz7dll9	22	36	and	and	CC
cord-023443-pvz7dll9	22	37	compared	compare	VBN
cord-023443-pvz7dll9	22	38	to	to	IN
cord-023443-pvz7dll9	22	39	MS	MS	NNP
cord-023443-pvz7dll9	22	40	(	(	-LRB-
cord-023443-pvz7dll9	22	41	3.8	3.8	CD
cord-023443-pvz7dll9	22	42	AE	AE	NNP
cord-023443-pvz7dll9	22	43	0.2	0.2	CD
cord-023443-pvz7dll9	22	44	;	;	:
cord-023443-pvz7dll9	22	45	n	n	NN
cord-023443-pvz7dll9	22	46	¼	¼	NNP
cord-023443-pvz7dll9	22	47	15	15	CD
cord-023443-pvz7dll9	22	48	;	;	:
cord-023443-pvz7dll9	22	49	P	p	NN
cord-023443-pvz7dll9	22	50	<	<	XX
cord-023443-pvz7dll9	22	51	0.001	0.001	CD
cord-023443-pvz7dll9	22	52	)	)	-RRB-
cord-023443-pvz7dll9	22	53	and	and	CC
cord-023443-pvz7dll9	22	54	HC	HC	NNP
cord-023443-pvz7dll9	22	55	(	(	-LRB-
cord-023443-pvz7dll9	22	56	4	4	CD
cord-023443-pvz7dll9	22	57	AE	AE	NNP
cord-023443-pvz7dll9	22	58	0.2	0.2	CD
cord-023443-pvz7dll9	22	59	;	;	:
cord-023443-pvz7dll9	22	60	n	n	NN
cord-023443-pvz7dll9	22	61	¼	¼	NNP
cord-023443-pvz7dll9	22	62	15	15	CD
cord-023443-pvz7dll9	22	63	;	;	:
cord-023443-pvz7dll9	22	64	P	p	NN
cord-023443-pvz7dll9	22	65	<	<	XX
cord-023443-pvz7dll9	22	66	0.001	0.001	CD
cord-023443-pvz7dll9	22	67	)	)	-RRB-
cord-023443-pvz7dll9	22	68	from	from	IN
cord-023443-pvz7dll9	22	69	Sardinia	Sardinia	NNP
cord-023443-pvz7dll9	22	70	.	.	.
cord-023443-pvz7dll9	23	1	MS	MS	NNP
cord-023443-pvz7dll9	23	2	patients	patient	NNS
cord-023443-pvz7dll9	23	3	from	from	IN
cord-023443-pvz7dll9	23	4	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	23	5	,	,	,
cord-023443-pvz7dll9	23	6	but	but	CC
cord-023443-pvz7dll9	23	7	not	not	RB
cord-023443-pvz7dll9	23	8	from	from	IN
cord-023443-pvz7dll9	23	9	Sassari	Sassari	NNP
cord-023443-pvz7dll9	23	10	,	,	,
cord-023443-pvz7dll9	23	11	also	also	RB
cord-023443-pvz7dll9	23	12	expressed	express	VBD
cord-023443-pvz7dll9	23	13	lower	low	JJR
cord-023443-pvz7dll9	23	14	(	(	-LRB-
cord-023443-pvz7dll9	23	15	P	p	NN
cord-023443-pvz7dll9	23	16	<	<	XX
cord-023443-pvz7dll9	23	17	0.05	0.05	CD
cord-023443-pvz7dll9	23	18	)	)	-RRB-
cord-023443-pvz7dll9	24	1	LXR	LXR	NNP
cord-023443-pvz7dll9	24	2	-	-	HYPH
cord-023443-pvz7dll9	24	3	b	b	NNP
cord-023443-pvz7dll9	24	4	(	(	-LRB-
cord-023443-pvz7dll9	24	5	À4.1	À4.1	NNP
cord-023443-pvz7dll9	24	6	AE	AE	NNP
cord-023443-pvz7dll9	24	7	0.4	0.4	CD
cord-023443-pvz7dll9	24	8	)	)	-RRB-
cord-023443-pvz7dll9	25	1	compared	compare	VBN
cord-023443-pvz7dll9	25	2	to	to	IN
cord-023443-pvz7dll9	25	3	corresponding	correspond	VBG
cord-023443-pvz7dll9	25	4	HC	HC	NNP
cord-023443-pvz7dll9	25	5	(	(	-LRB-
cord-023443-pvz7dll9	25	6	À2.9	À2.9	NNP
cord-023443-pvz7dll9	25	7	AE	AE	NNP
cord-023443-pvz7dll9	25	8	0.3	0.3	CD
cord-023443-pvz7dll9	25	9	)	)	-RRB-
cord-023443-pvz7dll9	25	10	.	.	.
cord-023443-pvz7dll9	26	1	MS	MS	NNP
cord-023443-pvz7dll9	26	2	from	from	IN
cord-023443-pvz7dll9	26	3	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	26	4	was	be	VBD
cord-023443-pvz7dll9	26	5	associated	associate	VBN
cord-023443-pvz7dll9	26	6	with	with	IN
cord-023443-pvz7dll9	26	7	higher	high	JJR
cord-023443-pvz7dll9	26	8	ABCA-1	ABCA-1	NNP
cord-023443-pvz7dll9	26	9	(	(	-LRB-
cord-023443-pvz7dll9	26	10	6.1	6.1	CD
cord-023443-pvz7dll9	26	11	AE	AE	NNP
cord-023443-pvz7dll9	26	12	0.4	0.4	CD
cord-023443-pvz7dll9	26	13	versus	versus	IN
cord-023443-pvz7dll9	26	14	5.0	5.0	CD
cord-023443-pvz7dll9	26	15	AE	AE	NNP
cord-023443-pvz7dll9	26	16	0.3	0.3	CD
cord-023443-pvz7dll9	26	17	;	;	:
cord-023443-pvz7dll9	26	18	P	p	NN
cord-023443-pvz7dll9	26	19	<	<	XX
cord-023443-pvz7dll9	26	20	0.05	0.05	CD
cord-023443-pvz7dll9	26	21	)	)	-RRB-
cord-023443-pvz7dll9	26	22	and	and	CC
cord-023443-pvz7dll9	26	23	higher	high	JJR
cord-023443-pvz7dll9	26	24	estrogen	estrogen	NN
cord-023443-pvz7dll9	26	25	receptor	receptor	NN
cord-023443-pvz7dll9	26	26	-	-	HYPH
cord-023443-pvz7dll9	26	27	b	b	NN
cord-023443-pvz7dll9	26	28	-	-	HYPH
cord-023443-pvz7dll9	26	29	Cx	cx	NN
cord-023443-pvz7dll9	26	30	(	(	-LRB-
cord-023443-pvz7dll9	26	31	2.4	2.4	CD
cord-023443-pvz7dll9	26	32	AE	AE	NNP
cord-023443-pvz7dll9	26	33	0.4	0.4	CD
cord-023443-pvz7dll9	26	34	versus	versus	IN
cord-023443-pvz7dll9	26	35	0.8	0.8	CD
cord-023443-pvz7dll9	26	36	AE	AE	NNP
cord-023443-pvz7dll9	26	37	0.4	0.4	CD
cord-023443-pvz7dll9	26	38	;	;	:
cord-023443-pvz7dll9	26	39	P	p	NN
cord-023443-pvz7dll9	26	40	<	<	XX
cord-023443-pvz7dll9	26	41	0.01	0.01	CD
cord-023443-pvz7dll9	26	42	)	)	-RRB-
cord-023443-pvz7dll9	26	43	compared	compare	VBN
cord-023443-pvz7dll9	26	44	to	to	IN
cord-023443-pvz7dll9	26	45	corresponding	correspond	VBG
cord-023443-pvz7dll9	26	46	HC	HC	NNP
cord-023443-pvz7dll9	26	47	.	.	.
cord-023443-pvz7dll9	27	1	The	the	DT
cord-023443-pvz7dll9	27	2	HC	HC	NNP
cord-023443-pvz7dll9	27	3	from	from	IN
cord-023443-pvz7dll9	27	4	Sassari	Sassari	NNP
cord-023443-pvz7dll9	27	5	had	have	VBD
cord-023443-pvz7dll9	27	6	higher	high	JJR
cord-023443-pvz7dll9	27	7	androgen	androgen	NN
cord-023443-pvz7dll9	27	8	receptor	receptor	NN
cord-023443-pvz7dll9	27	9	(	(	-LRB-
cord-023443-pvz7dll9	27	10	2.9	2.9	CD
cord-023443-pvz7dll9	27	11	AE	AE	NNP
cord-023443-pvz7dll9	27	12	0.2	0.2	CD
cord-023443-pvz7dll9	27	13	)	)	-RRB-
cord-023443-pvz7dll9	27	14	compared	compare	VBN
cord-023443-pvz7dll9	27	15	to	to	IN
cord-023443-pvz7dll9	27	16	MS	MS	NNP
cord-023443-pvz7dll9	27	17	from	from	IN
cord-023443-pvz7dll9	27	18	Sassari	Sassari	NNP
cord-023443-pvz7dll9	27	19	(	(	-LRB-
cord-023443-pvz7dll9	27	20	1.4	1.4	CD
cord-023443-pvz7dll9	27	21	AE	AE	NNP
cord-023443-pvz7dll9	27	22	0.3	0.3	CD
cord-023443-pvz7dll9	27	23	;	;	:
cord-023443-pvz7dll9	27	24	P	p	NN
cord-023443-pvz7dll9	27	25	<	<	XX
cord-023443-pvz7dll9	27	26	0.01	0.01	CD
cord-023443-pvz7dll9	27	27	)	)	-RRB-
cord-023443-pvz7dll9	27	28	,	,	,
cord-023443-pvz7dll9	27	29	MS	MS	NNP
cord-023443-pvz7dll9	27	30	(	(	-LRB-
cord-023443-pvz7dll9	27	31	1.3	1.3	CD
cord-023443-pvz7dll9	27	32	AE	AE	NNP
cord-023443-pvz7dll9	27	33	0.4	0.4	CD
cord-023443-pvz7dll9	27	34	;	;	:
cord-023443-pvz7dll9	27	35	P	p	NN
cord-023443-pvz7dll9	27	36	<	<	XX
cord-023443-pvz7dll9	27	37	0.01	0.01	CD
cord-023443-pvz7dll9	27	38	)	)	-RRB-
cord-023443-pvz7dll9	27	39	and	and	CC
cord-023443-pvz7dll9	27	40	HC	HC	NNP
cord-023443-pvz7dll9	27	41	from	from	IN
cord-023443-pvz7dll9	27	42	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	27	43	(	(	-LRB-
cord-023443-pvz7dll9	27	44	1.2	1.2	CD
cord-023443-pvz7dll9	27	45	AE	AE	NNP
cord-023443-pvz7dll9	27	46	0.3	0.3	CD
cord-023443-pvz7dll9	27	47	;	;	:
cord-023443-pvz7dll9	27	48	P	p	NN
cord-023443-pvz7dll9	27	49	<	<	XX
cord-023443-pvz7dll9	27	50	0.01	0.01	CD
cord-023443-pvz7dll9	27	51	)	)	-RRB-
cord-023443-pvz7dll9	27	52	.	.	.
cord-023443-pvz7dll9	28	1	MS	MS	NNP
cord-023443-pvz7dll9	28	2	from	from	IN
cord-023443-pvz7dll9	28	3	Sassari	Sassari	NNP
cord-023443-pvz7dll9	28	4	had	have	VBD
cord-023443-pvz7dll9	28	5	lower	low	JJR
cord-023443-pvz7dll9	28	6	cyclooxygenase-1	cyclooxygenase-1	NN
cord-023443-pvz7dll9	28	7	compared	compare	VBN
cord-023443-pvz7dll9	28	8	to	to	IN
cord-023443-pvz7dll9	28	9	corresponding	correspond	VBG
cord-023443-pvz7dll9	28	10	HC	HC	NNP
cord-023443-pvz7dll9	28	11	(	(	-LRB-
cord-023443-pvz7dll9	28	12	5.1	5.1	CD
cord-023443-pvz7dll9	28	13	AE	AE	NNP
cord-023443-pvz7dll9	28	14	0.4	0.4	CD
cord-023443-pvz7dll9	28	15	versus	versus	IN
cord-023443-pvz7dll9	28	16	6.6	6.6	CD
cord-023443-pvz7dll9	28	17	AE	AE	NNP
cord-023443-pvz7dll9	28	18	0.3	0.3	CD
cord-023443-pvz7dll9	28	19	;	;	:
cord-023443-pvz7dll9	28	20	P	p	NN
cord-023443-pvz7dll9	28	21	<	<	XX
cord-023443-pvz7dll9	28	22	0.01	0.01	CD
cord-023443-pvz7dll9	28	23	)	)	-RRB-
cord-023443-pvz7dll9	28	24	and	and	CC
cord-023443-pvz7dll9	28	25	lower	low	JJR
cord-023443-pvz7dll9	28	26	prostaglandin	prostaglandin	NN
cord-023443-pvz7dll9	28	27	-	-	HYPH
cord-023443-pvz7dll9	28	28	E	e	NN
cord-023443-pvz7dll9	28	29	(	(	-LRB-
cord-023443-pvz7dll9	28	30	À0.03	À0.03	NNP
cord-023443-pvz7dll9	28	31	AE	AE	NNP
cord-023443-pvz7dll9	28	32	0.5	0.5	CD
cord-023443-pvz7dll9	28	33	)	)	-RRB-
cord-023443-pvz7dll9	28	34	compared	compare	VBN
cord-023443-pvz7dll9	28	35	to	to	IN
cord-023443-pvz7dll9	28	36	the	the	DT
cord-023443-pvz7dll9	28	37	HC	HC	NNP
cord-023443-pvz7dll9	28	38	(	(	-LRB-
cord-023443-pvz7dll9	28	39	1.4	1.4	CD
cord-023443-pvz7dll9	28	40	AE	AE	NNP
cord-023443-pvz7dll9	28	41	0.5	0.5	CD
cord-023443-pvz7dll9	28	42	;	;	:
cord-023443-pvz7dll9	28	43	P	p	NN
cord-023443-pvz7dll9	28	44	<	<	XX
cord-023443-pvz7dll9	28	45	0.05	0.05	CD
cord-023443-pvz7dll9	28	46	)	)	-RRB-
cord-023443-pvz7dll9	28	47	and	and	CC
cord-023443-pvz7dll9	28	48	MS	MS	NNP
cord-023443-pvz7dll9	28	49	(	(	-LRB-
cord-023443-pvz7dll9	28	50	2.7	2.7	CD
cord-023443-pvz7dll9	28	51	AE	AE	NNP
cord-023443-pvz7dll9	28	52	0.4	0.4	CD
cord-023443-pvz7dll9	28	53	;	;	:
cord-023443-pvz7dll9	28	54	P	p	NN
cord-023443-pvz7dll9	28	55	<	<	XX
cord-023443-pvz7dll9	28	56	0.05	0.05	CD
cord-023443-pvz7dll9	28	57	)	)	-RRB-
cord-023443-pvz7dll9	28	58	and	and	CC
cord-023443-pvz7dll9	28	59	HC	HC	NNP
cord-023443-pvz7dll9	28	60	from	from	IN
cord-023443-pvz7dll9	28	61	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	28	62	(	(	-LRB-
cord-023443-pvz7dll9	28	63	1.9	1.9	CD
cord-023443-pvz7dll9	28	64	AE	AE	NNP
cord-023443-pvz7dll9	28	65	0.4	0.4	CD
cord-023443-pvz7dll9	28	66	,	,	,
cord-023443-pvz7dll9	28	67	P	p	NN
cord-023443-pvz7dll9	28	68	<	<	XX
cord-023443-pvz7dll9	28	69	0.001	0.001	CD
cord-023443-pvz7dll9	28	70	)	)	-RRB-
cord-023443-pvz7dll9	28	71	.	.	.
cord-023443-pvz7dll9	29	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	29	2	findings	finding	NNS
cord-023443-pvz7dll9	29	3	identify	identify	VBP
cord-023443-pvz7dll9	29	4	LXRs	lxr	NNS
cord-023443-pvz7dll9	29	5	and	and	CC
cord-023443-pvz7dll9	29	6	their	-PRON-	PRP$
cord-023443-pvz7dll9	29	7	related	related	JJ
cord-023443-pvz7dll9	29	8	molecules	molecule	NNS
cord-023443-pvz7dll9	29	9	as	as	IN
cord-023443-pvz7dll9	29	10	being	be	VBG
cord-023443-pvz7dll9	29	11	involved	involve	VBN
cord-023443-pvz7dll9	29	12	in	in	IN
cord-023443-pvz7dll9	29	13	MS	MS	NNP
cord-023443-pvz7dll9	29	14	from	from	IN
cord-023443-pvz7dll9	29	15	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	29	16	but	but	CC
cord-023443-pvz7dll9	29	17	not	not	RB
cord-023443-pvz7dll9	29	18	from	from	IN
cord-023443-pvz7dll9	29	19	Sassari	Sassari	NNP
cord-023443-pvz7dll9	29	20	,	,	,
cord-023443-pvz7dll9	29	21	while	while	IN
cord-023443-pvz7dll9	29	22	sex	sex	NN
cord-023443-pvz7dll9	29	23	hormone	hormone	NN
cord-023443-pvz7dll9	29	24	receptors	receptor	NNS
cord-023443-pvz7dll9	29	25	seem	seem	VBP
cord-023443-pvz7dll9	29	26	to	to	TO
cord-023443-pvz7dll9	29	27	be	be	VB
cord-023443-pvz7dll9	29	28	involved	involve	VBN
cord-023443-pvz7dll9	29	29	in	in	IN
cord-023443-pvz7dll9	29	30	MS	MS	NNP
cord-023443-pvz7dll9	29	31	in	in	IN
cord-023443-pvz7dll9	29	32	Sassari	Sassari	NNP
cord-023443-pvz7dll9	29	33	.	.	.
cord-023443-pvz7dll9	30	1	Multiple	multiple	JJ
cord-023443-pvz7dll9	30	2	Sclerosis	Sclerosis	NNP
cord-023443-pvz7dll9	30	3	:	:	:
cord-023443-pvz7dll9	30	4	IFN	IFN	NNP
cord-023443-pvz7dll9	30	5	-	-	HYPH
cord-023443-pvz7dll9	30	6	b	b	NNP
cord-023443-pvz7dll9	30	7	Induces	induce	VBZ
cord-023443-pvz7dll9	31	1	CD123	CD123	NNP
cord-023443-pvz7dll9	31	2	+	+	CC
cord-023443-pvz7dll9	32	1	BDCA2	BDCA2	NNP
cord-023443-pvz7dll9	32	2	-Dendritic	-Dendritic	NNP
cord-023443-pvz7dll9	33	1	Cells	cell	NNS
cord-023443-pvz7dll9	34	1	that	that	DT
cord-023443-pvz7dll9	34	2	Produce	Produce	NNP
cord-023443-pvz7dll9	34	3	IL-6	IL-6	NNP
cord-023443-pvz7dll9	34	4	and	and	CC
cord-023443-pvz7dll9	34	5	IL-10	IL-10	NNP
cord-023443-pvz7dll9	34	6	and	and	CC
cord-023443-pvz7dll9	34	7	have	have	VBP
cord-023443-pvz7dll9	34	8	No	no	DT
cord-023443-pvz7dll9	34	9	Enhanced	Enhanced	NNP
cord-023443-pvz7dll9	34	10	Type	type	NN
cord-023443-pvz7dll9	35	1	I	-PRON-	PRP
cord-023443-pvz7dll9	36	1	Interferon	Interferon	NNP
cord-023443-pvz7dll9	36	2	Production	Production	NNP
cord-023443-pvz7dll9	36	3	Y.	Y.	NNP
cord-023443-pvz7dll9	36	4	M.	M.	NNP
cord-023443-pvz7dll9	36	5	Huang	Huang	NNP
cord-023443-pvz7dll9	36	6	,	,	,
cord-023443-pvz7dll9	36	7	1	1	CD
cord-023443-pvz7dll9	36	8	S.	S.	NNP
cord-023443-pvz7dll9	36	9	Adikari	Adikari	NNP
cord-023443-pvz7dll9	36	10	,	,	,
cord-023443-pvz7dll9	36	11	1	1	CD
cord-023443-pvz7dll9	36	12	U.	U.	NNP
cord-023443-pvz7dll9	36	13	Båve	Båve	NNP
cord-023443-pvz7dll9	36	14	,	,	,
cord-023443-pvz7dll9	36	15	2	2	CD
cord-023443-pvz7dll9	36	16	A.	a.	NN
cord-023443-pvz7dll9	36	17	Sanna	Sanna	NNP
cord-023443-pvz7dll9	36	18	1,3	1,3	CD
cord-023443-pvz7dll9	36	19	&	&	CC
cord-023443-pvz7dll9	36	20	G.	G.	NNP
cord-023443-pvz7dll9	36	21	Alm	Alm	NNP
cord-023443-pvz7dll9	36	22	4	4	CD
cord-023443-pvz7dll9	36	23	DC	DC	NNP
cord-023443-pvz7dll9	36	24	antigens	antigen	NNS
cord-023443-pvz7dll9	36	25	(	(	-LRB-
cord-023443-pvz7dll9	36	26	BDCA	BDCA	NNP
cord-023443-pvz7dll9	36	27	)	)	-RRB-
cord-023443-pvz7dll9	36	28	and	and	CC
cord-023443-pvz7dll9	36	29	investigate	investigate	VB
cord-023443-pvz7dll9	36	30	their	-PRON-	PRP$
cord-023443-pvz7dll9	36	31	ability	ability	NN
cord-023443-pvz7dll9	36	32	to	to	TO
cord-023443-pvz7dll9	36	33	produce	produce	VB
cord-023443-pvz7dll9	36	34	Type	type	NN
cord-023443-pvz7dll9	36	35	I	-PRON-	PRP
cord-023443-pvz7dll9	36	36	IFN	IFN	NNP
cord-023443-pvz7dll9	36	37	in	in	IN
cord-023443-pvz7dll9	36	38	response	response	NN
cord-023443-pvz7dll9	36	39	to	to	IN
cord-023443-pvz7dll9	36	40	virus	virus	NN
cord-023443-pvz7dll9	36	41	stimulation	stimulation	NN
cord-023443-pvz7dll9	36	42	.	.	.
cord-023443-pvz7dll9	37	1	We	-PRON-	PRP
cord-023443-pvz7dll9	37	2	show	show	VBP
cord-023443-pvz7dll9	37	3	that	that	IN
cord-023443-pvz7dll9	37	4	IFN	IFN	NNP
cord-023443-pvz7dll9	37	5	-	-	HYPH
cord-023443-pvz7dll9	37	6	b	b	NNP
cord-023443-pvz7dll9	37	7	induces	induce	VBZ
cord-023443-pvz7dll9	37	8	development	development	NN
cord-023443-pvz7dll9	37	9	of	of	IN
cord-023443-pvz7dll9	37	10	CD123	CD123	NNP
cord-023443-pvz7dll9	37	11	þ	þ	NNP
cord-023443-pvz7dll9	37	12	DC	DC	NNP
cord-023443-pvz7dll9	37	13	from	from	IN
cord-023443-pvz7dll9	37	14	human	human	JJ
cord-023443-pvz7dll9	37	15	blood	blood	NN
cord-023443-pvz7dll9	37	16	monocytes	monocyte	NNS
cord-023443-pvz7dll9	37	17	,	,	,
cord-023443-pvz7dll9	37	18	which	which	WDT
cord-023443-pvz7dll9	37	19	coexpress	coexpress	VBP
cord-023443-pvz7dll9	37	20	BDCA4	bdca4	CC
cord-023443-pvz7dll9	37	21	þ	þ	NNP
cord-023443-pvz7dll9	37	22	but	but	CC
cord-023443-pvz7dll9	37	23	are	be	VBP
cord-023443-pvz7dll9	37	24	negative	negative	JJ
cord-023443-pvz7dll9	37	25	for	for	IN
cord-023443-pvz7dll9	37	26	BDCA2	BDCA2	NNP
cord-023443-pvz7dll9	37	27	-	-	HYPH
cord-023443-pvz7dll9	37	28	,	,	,
cord-023443-pvz7dll9	37	29	a	a	DT
cord-023443-pvz7dll9	37	30	specific	specific	JJ
cord-023443-pvz7dll9	37	31	marker	marker	NN
cord-023443-pvz7dll9	37	32	for	for	IN
cord-023443-pvz7dll9	37	33	plasmacytoid	plasmacytoid	NNP
cord-023443-pvz7dll9	37	34	DC	DC	NNP
cord-023443-pvz7dll9	37	35	.	.	.
cord-023443-pvz7dll9	38	1	Such	such	JJ
cord-023443-pvz7dll9	38	2	IFN	IFN	NNP
cord-023443-pvz7dll9	38	3	-	-	HYPH
cord-023443-pvz7dll9	38	4	b	b	NNP
cord-023443-pvz7dll9	38	5	-	-	HYPH
cord-023443-pvz7dll9	38	6	modulated	modulate	VBN
cord-023443-pvz7dll9	38	7	DC	DC	NNP
cord-023443-pvz7dll9	38	8	produce	produce	VB
cord-023443-pvz7dll9	38	9	large	large	JJ
cord-023443-pvz7dll9	38	10	amounts	amount	NNS
cord-023443-pvz7dll9	38	11	of	of	IN
cord-023443-pvz7dll9	38	12	IL-6	IL-6	NNP
cord-023443-pvz7dll9	38	13	and	and	CC
cord-023443-pvz7dll9	38	14	IL-10	IL-10	NNP
cord-023443-pvz7dll9	38	15	,	,	,
cord-023443-pvz7dll9	38	16	but	but	CC
cord-023443-pvz7dll9	38	17	no	no	DT
cord-023443-pvz7dll9	38	18	IL-12p40	IL-12p40	NNP
cord-023443-pvz7dll9	38	19	and	and	CC
cord-023443-pvz7dll9	38	20	have	have	VBP
cord-023443-pvz7dll9	38	21	no	no	DT
cord-023443-pvz7dll9	38	22	enhanced	enhance	VBN
cord-023443-pvz7dll9	38	23	IFN	IFN	NNP
cord-023443-pvz7dll9	38	24	-	-	HYPH
cord-023443-pvz7dll9	38	25	b	b	NNP
cord-023443-pvz7dll9	38	26	and	and	CC
cord-023443-pvz7dll9	38	27	IFN	IFN	NNP
cord-023443-pvz7dll9	38	28	-	-	HYPH
cord-023443-pvz7dll9	38	29	b	b	NN
cord-023443-pvz7dll9	38	30	production	production	NN
cord-023443-pvz7dll9	38	31	.	.	.
cord-023443-pvz7dll9	39	1	The	the	DT
cord-023443-pvz7dll9	39	2	findings	finding	NNS
cord-023443-pvz7dll9	39	3	indicate	indicate	VBP
cord-023443-pvz7dll9	39	4	that	that	IN
cord-023443-pvz7dll9	39	5	IFN	IFN	NNP
cord-023443-pvz7dll9	39	6	-	-	HYPH
cord-023443-pvz7dll9	39	7	bmodulated	bmodulate	VBN
cord-023443-pvz7dll9	39	8	DC	DC	NNP
cord-023443-pvz7dll9	39	9	represent	represent	VBP
cord-023443-pvz7dll9	39	10	a	a	DT
cord-023443-pvz7dll9	39	11	myeloid	myeloid	JJ
cord-023443-pvz7dll9	39	12	DC	DC	NNP
cord-023443-pvz7dll9	39	13	subset	subset	VBN
cord-023443-pvz7dll9	39	14	with	with	IN
cord-023443-pvz7dll9	39	15	diminished	diminished	JJ
cord-023443-pvz7dll9	39	16	CD11c	CD11c	NNP
cord-023443-pvz7dll9	39	17	,	,	,
cord-023443-pvz7dll9	39	18	BDCA-1	BDCA-1	NNP
cord-023443-pvz7dll9	39	19	and	and	CC
cord-023443-pvz7dll9	39	20	CD1a	CD1a	NNP
cord-023443-pvz7dll9	39	21	expression	expression	NN
cord-023443-pvz7dll9	39	22	,	,	,
cord-023443-pvz7dll9	39	23	having	have	VBG
cord-023443-pvz7dll9	39	24	potent	potent	JJ
cord-023443-pvz7dll9	39	25	Th2-promoting	th2-promoting	CD
cord-023443-pvz7dll9	39	26	function	function	NN
cord-023443-pvz7dll9	39	27	but	but	CC
cord-023443-pvz7dll9	39	28	lacking	lack	VBG
cord-023443-pvz7dll9	39	29	antiviral	antiviral	JJ
cord-023443-pvz7dll9	39	30	capacity	capacity	NN
cord-023443-pvz7dll9	39	31	.	.	.
cord-023443-pvz7dll9	40	1	The	the	DT
cord-023443-pvz7dll9	40	2	association	association	NN
cord-023443-pvz7dll9	40	3	of	of	IN
cord-023443-pvz7dll9	40	4	psoriasis	psoriasis	NNP
cord-023443-pvz7dll9	40	5	with	with	IN
cord-023443-pvz7dll9	40	6	throat	throat	NN
cord-023443-pvz7dll9	40	7	infections	infection	NNS
cord-023443-pvz7dll9	40	8	by	by	IN
cord-023443-pvz7dll9	40	9	streptococcus	streptococcus	NN
cord-023443-pvz7dll9	40	10	pyogenes	pyogene	NNS
cord-023443-pvz7dll9	40	11	suggests	suggest	VBZ
cord-023443-pvz7dll9	40	12	a	a	DT
cord-023443-pvz7dll9	40	13	potential	potential	JJ
cord-023443-pvz7dll9	40	14	antigenic	antigenic	JJ
cord-023443-pvz7dll9	40	15	target	target	NN
cord-023443-pvz7dll9	40	16	for	for	IN
cord-023443-pvz7dll9	40	17	the	the	DT
cord-023443-pvz7dll9	40	18	T	t	NN
cord-023443-pvz7dll9	40	19	cells	cell	NNS
cord-023443-pvz7dll9	40	20	that	that	WDT
cord-023443-pvz7dll9	40	21	are	be	VBP
cord-023443-pvz7dll9	40	22	known	know	VBN
cord-023443-pvz7dll9	40	23	to	to	TO
cord-023443-pvz7dll9	40	24	infiltrate	infiltrate	VB
cord-023443-pvz7dll9	40	25	dermis	dermis	NN
cord-023443-pvz7dll9	40	26	and	and	CC
cord-023443-pvz7dll9	40	27	epidermis	epidermis	NN
cord-023443-pvz7dll9	40	28	of	of	IN
cord-023443-pvz7dll9	40	29	psoriatic	psoriatic	JJ
cord-023443-pvz7dll9	40	30	skin	skin	NN
cord-023443-pvz7dll9	40	31	.	.	.
cord-023443-pvz7dll9	41	1	Streptococcal	Streptococcal	NNP
cord-023443-pvz7dll9	41	2	M	M	NNP
cord-023443-pvz7dll9	41	3	protein	protein	NN
cord-023443-pvz7dll9	41	4	shares	share	VBZ
cord-023443-pvz7dll9	41	5	an	an	DT
cord-023443-pvz7dll9	41	6	extensive	extensive	JJ
cord-023443-pvz7dll9	41	7	sequence	sequence	NN
cord-023443-pvz7dll9	41	8	homology	homology	NN
cord-023443-pvz7dll9	41	9	with	with	IN
cord-023443-pvz7dll9	41	10	human	human	JJ
cord-023443-pvz7dll9	41	11	epidermal	epidermal	JJ
cord-023443-pvz7dll9	41	12	keratins	keratin	NNS
cord-023443-pvz7dll9	41	13	.	.	.
cord-023443-pvz7dll9	42	1	Keratins	keratin	NNS
cord-023443-pvz7dll9	42	2	16	16	CD
cord-023443-pvz7dll9	42	3	(	(	-LRB-
cord-023443-pvz7dll9	42	4	K16	K16	NNP
cord-023443-pvz7dll9	42	5	)	)	-RRB-
cord-023443-pvz7dll9	42	6	and	and	CC
cord-023443-pvz7dll9	42	7	17	17	CD
cord-023443-pvz7dll9	42	8	(	(	-LRB-
cord-023443-pvz7dll9	42	9	K17	K17	NNP
cord-023443-pvz7dll9	42	10	)	)	-RRB-
cord-023443-pvz7dll9	42	11	are	be	VBP
cord-023443-pvz7dll9	42	12	mostly	mostly	RB
cord-023443-pvz7dll9	42	13	absent	absent	JJ
cord-023443-pvz7dll9	42	14	from	from	IN
cord-023443-pvz7dll9	42	15	uninvolved	uninvolved	JJ
cord-023443-pvz7dll9	42	16	skin	skin	NN
cord-023443-pvz7dll9	42	17	but	but	CC
cord-023443-pvz7dll9	42	18	are	be	VBP
cord-023443-pvz7dll9	42	19	upregulated	upregulate	VBN
cord-023443-pvz7dll9	42	20	in	in	IN
cord-023443-pvz7dll9	42	21	psoriatic	psoriatic	JJ
cord-023443-pvz7dll9	42	22	lesions	lesion	NNS
cord-023443-pvz7dll9	42	23	.	.	.
cord-023443-pvz7dll9	43	1	There	there	EX
cord-023443-pvz7dll9	43	2	is	be	VBZ
cord-023443-pvz7dll9	43	3	increasing	increase	VBG
cord-023443-pvz7dll9	43	4	evidence	evidence	NN
cord-023443-pvz7dll9	43	5	that	that	IN
cord-023443-pvz7dll9	43	6	CD8	CD8	NNP
cord-023443-pvz7dll9	43	7	þ	þ	NNP
cord-023443-pvz7dll9	43	8	T	T	NNP
cord-023443-pvz7dll9	43	9	cells	cell	NNS
cord-023443-pvz7dll9	43	10	play	play	VBP
cord-023443-pvz7dll9	43	11	an	an	DT
cord-023443-pvz7dll9	43	12	important	important	JJ
cord-023443-pvz7dll9	43	13	effector	effector	NN
cord-023443-pvz7dll9	43	14	role	role	NN
cord-023443-pvz7dll9	43	15	in	in	IN
cord-023443-pvz7dll9	43	16	psoriasis	psoriasis	NN
cord-023443-pvz7dll9	43	17	and	and	CC
cord-023443-pvz7dll9	43	18	M	M	NNP
cord-023443-pvz7dll9	43	19	proteinprimed	proteinprimed	NNP
cord-023443-pvz7dll9	43	20	T	T	NNP
cord-023443-pvz7dll9	43	21	cells	cell	NNS
cord-023443-pvz7dll9	43	22	may	may	MD
cord-023443-pvz7dll9	43	23	recognize	recognize	VB
cord-023443-pvz7dll9	43	24	these	these	DT
cord-023443-pvz7dll9	43	25	shared	share	VBN
cord-023443-pvz7dll9	43	26	epitopes	epitope	NNS
cord-023443-pvz7dll9	43	27	in	in	IN
cord-023443-pvz7dll9	43	28	skin	skin	NN
cord-023443-pvz7dll9	43	29	via	via	IN
cord-023443-pvz7dll9	43	30	molecular	molecular	JJ
cord-023443-pvz7dll9	43	31	mimicry	mimicry	NN
cord-023443-pvz7dll9	43	32	.	.	.
cord-023443-pvz7dll9	44	1	To	to	TO
cord-023443-pvz7dll9	44	2	identify	identify	VB
cord-023443-pvz7dll9	44	3	candidate	candidate	NN
cord-023443-pvz7dll9	44	4	epitopes	epitope	NNS
cord-023443-pvz7dll9	44	5	,	,	,
cord-023443-pvz7dll9	44	6	peptides	peptide	NNS
cord-023443-pvz7dll9	44	7	with	with	IN
cord-023443-pvz7dll9	44	8	sequences	sequence	NNS
cord-023443-pvz7dll9	44	9	from	from	IN
cord-023443-pvz7dll9	44	10	K17	K17	NNP
cord-023443-pvz7dll9	44	11	were	be	VBD
cord-023443-pvz7dll9	44	12	selected	select	VBN
cord-023443-pvz7dll9	44	13	on	on	IN
cord-023443-pvz7dll9	44	14	the	the	DT
cord-023443-pvz7dll9	44	15	basis	basis	NN
cord-023443-pvz7dll9	44	16	of	of	IN
cord-023443-pvz7dll9	44	17	predicted	predict	VBN
cord-023443-pvz7dll9	44	18	binding	bind	VBG
cord-023443-pvz7dll9	44	19	to	to	IN
cord-023443-pvz7dll9	44	20	HLA	HLA	NNP
cord-023443-pvz7dll9	44	21	-	-	HYPH
cord-023443-pvz7dll9	44	22	Cw6	cw6	NN
cord-023443-pvz7dll9	44	23	and	and	CC
cord-023443-pvz7dll9	44	24	sequence	sequence	NN
cord-023443-pvz7dll9	44	25	similarities	similarity	NNS
cord-023443-pvz7dll9	44	26	with	with	IN
cord-023443-pvz7dll9	44	27	M6	m6	JJ
cord-023443-pvz7dll9	44	28	protein	protein	NN
cord-023443-pvz7dll9	44	29	.	.	.
cord-023443-pvz7dll9	45	1	Matched	match	VBN
cord-023443-pvz7dll9	45	2	peptides	peptide	NNS
cord-023443-pvz7dll9	45	3	from	from	IN
cord-023443-pvz7dll9	45	4	the	the	DT
cord-023443-pvz7dll9	45	5	sequence	sequence	NN
cord-023443-pvz7dll9	45	6	of	of	IN
cord-023443-pvz7dll9	45	7	M6	m6	JJ
cord-023443-pvz7dll9	45	8	protein	protein	NN
cord-023443-pvz7dll9	45	9	and	and	CC
cord-023443-pvz7dll9	45	10	a	a	DT
cord-023443-pvz7dll9	45	11	set	set	NN
cord-023443-pvz7dll9	45	12	of	of	IN
cord-023443-pvz7dll9	45	13	peptides	peptide	NNS
cord-023443-pvz7dll9	45	14	with	with	IN
cord-023443-pvz7dll9	45	15	poor	poor	JJ
cord-023443-pvz7dll9	45	16	predicted	predict	VBN
cord-023443-pvz7dll9	45	17	binding	binding	NN
cord-023443-pvz7dll9	45	18	were	be	VBD
cord-023443-pvz7dll9	45	19	also	also	RB
cord-023443-pvz7dll9	45	20	selected	select	VBN
cord-023443-pvz7dll9	45	21	.	.	.
cord-023443-pvz7dll9	46	1	Cw6	Cw6	NNP
cord-023443-pvz7dll9	46	2	þ	þ	NNP
cord-023443-pvz7dll9	46	3	individuals	individual	NNS
cord-023443-pvz7dll9	46	4	with	with	IN
cord-023443-pvz7dll9	46	5	psoriasis	psoriasis	NN
cord-023443-pvz7dll9	46	6	and	and	CC
cord-023443-pvz7dll9	46	7	Cw6	cw6	VBP
cord-023443-pvz7dll9	46	8	þ	þ	NNP
cord-023443-pvz7dll9	46	9	healthy	healthy	JJ
cord-023443-pvz7dll9	46	10	controls	control	NNS
cord-023443-pvz7dll9	46	11	,	,	,
cord-023443-pvz7dll9	46	12	having	have	VBG
cord-023443-pvz7dll9	46	13	a	a	DT
cord-023443-pvz7dll9	46	14	family	family	NN
cord-023443-pvz7dll9	46	15	history	history	NN
cord-023443-pvz7dll9	46	16	of	of	IN
cord-023443-pvz7dll9	46	17	psoriasis	psoriasis	NN
cord-023443-pvz7dll9	46	18	,	,	,
cord-023443-pvz7dll9	46	19	were	be	VBD
cord-023443-pvz7dll9	46	20	recruited	recruit	VBN
cord-023443-pvz7dll9	46	21	.	.	.
cord-023443-pvz7dll9	47	1	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	47	2	were	be	VBD
cord-023443-pvz7dll9	47	3	incubated	incubate	VBN
cord-023443-pvz7dll9	47	4	with	with	IN
cord-023443-pvz7dll9	47	5	the	the	DT
cord-023443-pvz7dll9	47	6	peptide	peptide	NN
cord-023443-pvz7dll9	47	7	antigens	antigen	NNS
cord-023443-pvz7dll9	47	8	.	.	.
cord-023443-pvz7dll9	48	1	T	t	NN
cord-023443-pvz7dll9	48	2	-	-	HYPH
cord-023443-pvz7dll9	48	3	cell	cell	NN
cord-023443-pvz7dll9	48	4	activation	activation	NN
cord-023443-pvz7dll9	48	5	in	in	IN
cord-023443-pvz7dll9	48	6	the	the	DT
cord-023443-pvz7dll9	48	7	CD4	CD4	NNP
cord-023443-pvz7dll9	48	8	þ	þ	NNP
cord-023443-pvz7dll9	48	9	,	,	,
cord-023443-pvz7dll9	48	10	CD8	CD8	NNP
cord-023443-pvz7dll9	48	11	þ	þ	NNP
cord-023443-pvz7dll9	48	12	and	and	CC
cord-023443-pvz7dll9	48	13	later	later	RBR
cord-023443-pvz7dll9	48	14	the	the	DT
cord-023443-pvz7dll9	48	15	skin	skin	NN
cord-023443-pvz7dll9	48	16	-	-	HYPH
cord-023443-pvz7dll9	48	17	homing	home	VBG
cord-023443-pvz7dll9	48	18	cutaneous	cutaneous	JJ
cord-023443-pvz7dll9	48	19	lymphocyteassociated	lymphocyteassociated	JJ
cord-023443-pvz7dll9	48	20	antigen	antigen	NN
cord-023443-pvz7dll9	48	21	(	(	-LRB-
cord-023443-pvz7dll9	48	22	CLA)-expressing	cla)-expresse	VBG
cord-023443-pvz7dll9	48	23	subset	subset	NN
cord-023443-pvz7dll9	48	24	of	of	IN
cord-023443-pvz7dll9	48	25	CD8	CD8	NNP
cord-023443-pvz7dll9	48	26	þ	þ	NNP
cord-023443-pvz7dll9	48	27	T	T	NNP
cord-023443-pvz7dll9	48	28	cells	cell	NNS
cord-023443-pvz7dll9	48	29	was	be	VBD
cord-023443-pvz7dll9	48	30	evaluated	evaluate	VBN
cord-023443-pvz7dll9	48	31	by	by	IN
cord-023443-pvz7dll9	48	32	CD69	CD69	NNP
cord-023443-pvz7dll9	48	33	expression	expression	NN
cord-023443-pvz7dll9	48	34	and	and	CC
cord-023443-pvz7dll9	48	35	intracellular	intracellular	JJ
cord-023443-pvz7dll9	48	36	IFN	IFN	NNP
cord-023443-pvz7dll9	48	37	-	-	HYPH
cord-023443-pvz7dll9	48	38	g	g	NN
cord-023443-pvz7dll9	48	39	accumulation	accumulation	NN
cord-023443-pvz7dll9	48	40	using	use	VBG
cord-023443-pvz7dll9	48	41	flow	flow	NN
cord-023443-pvz7dll9	48	42	cytometry	cytometry	NN
cord-023443-pvz7dll9	48	43	.	.	.
cord-023443-pvz7dll9	49	1	We	-PRON-	PRP
cord-023443-pvz7dll9	49	2	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	49	3	that	that	IN
cord-023443-pvz7dll9	49	4	Cw6	cw6	NN
cord-023443-pvz7dll9	49	5	þ	þ	CD
cord-023443-pvz7dll9	49	6	psoriasis	psoriasis	NN
cord-023443-pvz7dll9	49	7	patients	patient	NNS
cord-023443-pvz7dll9	49	8	had	have	VBD
cord-023443-pvz7dll9	49	9	significant	significant	JJ
cord-023443-pvz7dll9	49	10	CD8	CD8	NNP
cord-023443-pvz7dll9	49	11	þ	þ	NNP
cord-023443-pvz7dll9	49	12	T	T	NNP
cord-023443-pvz7dll9	49	13	-	-	HYPH
cord-023443-pvz7dll9	49	14	cell	cell	NN
cord-023443-pvz7dll9	49	15	IFN	IFN	NNP
cord-023443-pvz7dll9	49	16	-	-	HYPH
cord-023443-pvz7dll9	49	17	g	g	NNP
cord-023443-pvz7dll9	49	18	responses	response	NNS
cord-023443-pvz7dll9	49	19	to	to	IN
cord-023443-pvz7dll9	49	20	peptides	peptide	NNS
cord-023443-pvz7dll9	49	21	from	from	IN
cord-023443-pvz7dll9	49	22	K17	K17	NNP
cord-023443-pvz7dll9	49	23	and	and	CC
cord-023443-pvz7dll9	49	24	M6	M6	NNP
cord-023443-pvz7dll9	49	25	protein	protein	NN
cord-023443-pvz7dll9	49	26	selected	select	VBN
cord-023443-pvz7dll9	49	27	on	on	IN
cord-023443-pvz7dll9	49	28	the	the	DT
cord-023443-pvz7dll9	49	29	basis	basis	NN
cord-023443-pvz7dll9	49	30	of	of	IN
cord-023443-pvz7dll9	49	31	sequence	sequence	NN
cord-023443-pvz7dll9	49	32	homology	homology	NN
cord-023443-pvz7dll9	49	33	and	and	CC
cord-023443-pvz7dll9	49	34	predicted	predict	VBD
cord-023443-pvz7dll9	49	35	HLA	HLA	NNP
cord-023443-pvz7dll9	49	36	-	-	HYPH
cord-023443-pvz7dll9	49	37	Cw*0602	cw*0602	NN
cord-023443-pvz7dll9	49	38	binding	binding	NN
cord-023443-pvz7dll9	49	39	.	.	.
cord-023443-pvz7dll9	50	1	These	these	DT
cord-023443-pvz7dll9	50	2	responses	response	NNS
cord-023443-pvz7dll9	50	3	were	be	VBD
cord-023443-pvz7dll9	50	4	about	about	RB
cord-023443-pvz7dll9	50	5	10	10	CD
cord-023443-pvz7dll9	50	6	times	time	NNS
cord-023443-pvz7dll9	50	7	more	more	RBR
cord-023443-pvz7dll9	50	8	frequent	frequent	JJ
cord-023443-pvz7dll9	50	9	in	in	IN
cord-023443-pvz7dll9	50	10	the	the	DT
cord-023443-pvz7dll9	50	11	skin	skin	NN
cord-023443-pvz7dll9	50	12	-	-	HYPH
cord-023443-pvz7dll9	50	13	homing	home	VBG
cord-023443-pvz7dll9	50	14	cutaneous	cutaneous	JJ
cord-023443-pvz7dll9	50	15	lymphocyte	lymphocyte	NN
cord-023443-pvz7dll9	50	16	-	-	HYPH
cord-023443-pvz7dll9	50	17	associated	associate	VBN
cord-023443-pvz7dll9	50	18	antigen	antigen	NN
cord-023443-pvz7dll9	50	19	-	-	HYPH
cord-023443-pvz7dll9	50	20	expressing	express	VBG
cord-023443-pvz7dll9	51	1	(	(	-LRB-
cord-023443-pvz7dll9	51	2	CLA	CLA	NNP
cord-023443-pvz7dll9	51	3	þ	þ	NNP
cord-023443-pvz7dll9	51	4	)	)	-RRB-
cord-023443-pvz7dll9	52	1	subset	subset	VBN
cord-023443-pvz7dll9	52	2	of	of	IN
cord-023443-pvz7dll9	52	3	CD8	CD8	NNP
cord-023443-pvz7dll9	52	4	þ	þ	NNP
cord-023443-pvz7dll9	52	5	T	T	NNP
cord-023443-pvz7dll9	52	6	cells	cell	NNS
cord-023443-pvz7dll9	52	7	.	.	.
cord-023443-pvz7dll9	53	1	CD4	CD4	NNP
cord-023443-pvz7dll9	53	2	þ	þ	NNP
cord-023443-pvz7dll9	53	3	T	t	NN
cord-023443-pvz7dll9	53	4	cells	cell	NNS
cord-023443-pvz7dll9	53	5	showed	show	VBD
cord-023443-pvz7dll9	53	6	only	only	RB
cord-023443-pvz7dll9	53	7	borderline	borderline	JJ
cord-023443-pvz7dll9	53	8	responses	response	NNS
cord-023443-pvz7dll9	53	9	.	.	.
cord-023443-pvz7dll9	54	1	CD8	CD8	NNP
cord-023443-pvz7dll9	54	2	þ	þ	NNP
cord-023443-pvz7dll9	54	3	T	T	NNP
cord-023443-pvz7dll9	54	4	cells	cell	NNS
cord-023443-pvz7dll9	54	5	from	from	IN
cord-023443-pvz7dll9	54	6	Cw6	cw6	NN
cord-023443-pvz7dll9	54	7	þ	þ	NNP
cord-023443-pvz7dll9	54	8	nonpsoriatic	nonpsoriatic	JJ
cord-023443-pvz7dll9	54	9	individuals	individual	NNS
cord-023443-pvz7dll9	54	10	responded	respond	VBD
cord-023443-pvz7dll9	54	11	to	to	IN
cord-023443-pvz7dll9	54	12	some	some	DT
cord-023443-pvz7dll9	54	13	M6	m6	JJ
cord-023443-pvz7dll9	54	14	peptides	peptide	NNS
cord-023443-pvz7dll9	54	15	but	but	CC
cord-023443-pvz7dll9	54	16	very	very	RB
cord-023443-pvz7dll9	54	17	rarely	rarely	RB
cord-023443-pvz7dll9	54	18	to	to	IN
cord-023443-pvz7dll9	54	19	K17	K17	NNP
cord-023443-pvz7dll9	54	20	peptides	peptide	NNS
cord-023443-pvz7dll9	54	21	,	,	,
cord-023443-pvz7dll9	54	22	and	and	CC
cord-023443-pvz7dll9	54	23	this	this	DT
cord-023443-pvz7dll9	54	24	also	also	RB
cord-023443-pvz7dll9	54	25	applied	apply	VBD
cord-023443-pvz7dll9	54	26	to	to	IN
cord-023443-pvz7dll9	54	27	the	the	DT
cord-023443-pvz7dll9	54	28	CLA	CLA	NNP
cord-023443-pvz7dll9	54	29	þ	þ	NNP
cord-023443-pvz7dll9	54	30	CD8	CD8	NNP
cord-023443-pvz7dll9	54	31	þ	þ	NNP
cord-023443-pvz7dll9	54	32	subset	subset	JJ
cord-023443-pvz7dll9	54	33	.	.	.
cord-023443-pvz7dll9	55	1	These	these	DT
cord-023443-pvz7dll9	55	2	findings	finding	NNS
cord-023443-pvz7dll9	55	3	indicate	indicate	VBP
cord-023443-pvz7dll9	55	4	that	that	IN
cord-023443-pvz7dll9	55	5	psoriatic	psoriatic	JJ
cord-023443-pvz7dll9	55	6	individuals	individual	NNS
cord-023443-pvz7dll9	55	7	have	have	VBP
cord-023443-pvz7dll9	55	8	CD8	CD8	NNP
cord-023443-pvz7dll9	55	9	þ	þ	NNP
cord-023443-pvz7dll9	55	10	T	T	NNP
cord-023443-pvz7dll9	55	11	cells	cell	NNS
cord-023443-pvz7dll9	55	12	that	that	WDT
cord-023443-pvz7dll9	55	13	recognize	recognize	VBP
cord-023443-pvz7dll9	55	14	keratin	keratin	NN
cord-023443-pvz7dll9	55	15	self	self	NN
cord-023443-pvz7dll9	55	16	-	-	HYPH
cord-023443-pvz7dll9	55	17	antigens	antigen	NNS
cord-023443-pvz7dll9	55	18	and	and	CC
cord-023443-pvz7dll9	55	19	that	that	IN
cord-023443-pvz7dll9	55	20	epitopes	epitope	NNS
cord-023443-pvz7dll9	55	21	shared	share	VBN
cord-023443-pvz7dll9	55	22	by	by	IN
cord-023443-pvz7dll9	55	23	streptococcal	streptococcal	JJ
cord-023443-pvz7dll9	55	24	M	M	NNP
cord-023443-pvz7dll9	55	25	protein	protein	NN
cord-023443-pvz7dll9	55	26	and	and	CC
cord-023443-pvz7dll9	55	27	human	human	JJ
cord-023443-pvz7dll9	55	28	keratin	keratin	NN
cord-023443-pvz7dll9	55	29	may	may	MD
cord-023443-pvz7dll9	55	30	be	be	VB
cord-023443-pvz7dll9	55	31	targets	target	NNS
cord-023443-pvz7dll9	55	32	for	for	IN
cord-023443-pvz7dll9	55	33	the	the	DT
cord-023443-pvz7dll9	55	34	CD8	CD8	NNP
cord-023443-pvz7dll9	55	35	þ	þ	NNP
cord-023443-pvz7dll9	55	36	T	T	NNP
cord-023443-pvz7dll9	55	37	cells	cell	NNS
cord-023443-pvz7dll9	55	38	that	that	WDT
cord-023443-pvz7dll9	55	39	infiltrate	infiltrate	VBP
cord-023443-pvz7dll9	55	40	psoriatic	psoriatic	JJ
cord-023443-pvz7dll9	55	41	skin	skin	NN
cord-023443-pvz7dll9	55	42	lesions	lesion	NNS
cord-023443-pvz7dll9	55	43	.	.	.
cord-023443-pvz7dll9	56	1	Autoantibodies	Autoantibodies	NNP
cord-023443-pvz7dll9	56	2	directed	direct	VBN
cord-023443-pvz7dll9	56	3	against	against	IN
cord-023443-pvz7dll9	56	4	citrulline	citrulline	NN
cord-023443-pvz7dll9	56	5	-	-	HYPH
cord-023443-pvz7dll9	56	6	containing	contain	VBG
cord-023443-pvz7dll9	56	7	proteins	protein	NNS
cord-023443-pvz7dll9	56	8	have	have	VBP
cord-023443-pvz7dll9	56	9	an	an	DT
cord-023443-pvz7dll9	56	10	impressive	impressive	JJ
cord-023443-pvz7dll9	56	11	specificity	specificity	NN
cord-023443-pvz7dll9	56	12	of	of	IN
cord-023443-pvz7dll9	56	13	nearly	nearly	RB
cord-023443-pvz7dll9	56	14	100	100	CD
cord-023443-pvz7dll9	56	15	%	%	NN
cord-023443-pvz7dll9	56	16	in	in	IN
cord-023443-pvz7dll9	56	17	RA	RA	NNP
cord-023443-pvz7dll9	56	18	patients	patient	NNS
cord-023443-pvz7dll9	56	19	and	and	CC
cord-023443-pvz7dll9	56	20	a	a	DT
cord-023443-pvz7dll9	56	21	suggestive	suggestive	JJ
cord-023443-pvz7dll9	56	22	involvement	involvement	NN
cord-023443-pvz7dll9	56	23	in	in	IN
cord-023443-pvz7dll9	56	24	the	the	DT
cord-023443-pvz7dll9	56	25	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	56	26	.	.	.
cord-023443-pvz7dll9	57	1	The	the	DT
cord-023443-pvz7dll9	57	2	targeted	target	VBN
cord-023443-pvz7dll9	57	3	epitopes	epitope	NNS
cord-023443-pvz7dll9	57	4	are	be	VBP
cord-023443-pvz7dll9	57	5	generated	generate	VBN
cord-023443-pvz7dll9	57	6	by	by	IN
cord-023443-pvz7dll9	57	7	a	a	DT
cord-023443-pvz7dll9	57	8	post	post	JJ
cord-023443-pvz7dll9	57	9	-	-	JJ
cord-023443-pvz7dll9	57	10	translational	translational	JJ
cord-023443-pvz7dll9	57	11	modification	modification	NN
cord-023443-pvz7dll9	57	12	catalysed	catalyse	VBN
cord-023443-pvz7dll9	57	13	by	by	IN
cord-023443-pvz7dll9	58	1	the	the	DT
cord-023443-pvz7dll9	58	2	calcium	calcium	NN
cord-023443-pvz7dll9	58	3	-	-	HYPH
cord-023443-pvz7dll9	58	4	dependent	dependent	JJ
cord-023443-pvz7dll9	58	5	enzyme	enzyme	NN
cord-023443-pvz7dll9	58	6	peptidyl	peptidyl	NNP
cord-023443-pvz7dll9	58	7	arginine	arginine	NN
cord-023443-pvz7dll9	58	8	deaminase	deaminase	NNP
cord-023443-pvz7dll9	58	9	that	that	WDT
cord-023443-pvz7dll9	58	10	converts	convert	VBZ
cord-023443-pvz7dll9	58	11	the	the	DT
cord-023443-pvz7dll9	58	12	positively	positively	RB
cord-023443-pvz7dll9	58	13	charged	charge	VBN
cord-023443-pvz7dll9	58	14	arginine	arginine	NN
cord-023443-pvz7dll9	58	15	to	to	IN
cord-023443-pvz7dll9	58	16	polar	polar	JJ
cord-023443-pvz7dll9	58	17	but	but	CC
cord-023443-pvz7dll9	58	18	uncharged	uncharged	JJ
cord-023443-pvz7dll9	58	19	citrullin	citrullin	NNP
cord-023443-pvz7dll9	58	20	.	.	.
cord-023443-pvz7dll9	59	1	The	the	DT
cord-023443-pvz7dll9	59	2	aim	aim	NN
cord-023443-pvz7dll9	59	3	of	of	IN
cord-023443-pvz7dll9	59	4	this	this	DT
cord-023443-pvz7dll9	59	5	study	study	NN
cord-023443-pvz7dll9	59	6	was	be	VBD
cord-023443-pvz7dll9	59	7	to	to	TO
cord-023443-pvz7dll9	59	8	analyse	analyse	VB
cord-023443-pvz7dll9	59	9	the	the	DT
cord-023443-pvz7dll9	59	10	presence	presence	NN
cord-023443-pvz7dll9	59	11	of	of	IN
cord-023443-pvz7dll9	59	12	citrulline	citrulline	NN
cord-023443-pvz7dll9	59	13	in	in	IN
cord-023443-pvz7dll9	59	14	the	the	DT
cord-023443-pvz7dll9	59	15	joints	joint	NNS
cord-023443-pvz7dll9	59	16	at	at	IN
cord-023443-pvz7dll9	59	17	different	different	JJ
cord-023443-pvz7dll9	59	18	time	time	NN
cord-023443-pvz7dll9	59	19	points	point	NNS
cord-023443-pvz7dll9	59	20	of	of	IN
cord-023443-pvz7dll9	59	21	collagen	collagen	NN
cord-023443-pvz7dll9	59	22	-	-	HYPH
cord-023443-pvz7dll9	59	23	induced	induce	VBN
cord-023443-pvz7dll9	59	24	arthritis	arthritis	NN
cord-023443-pvz7dll9	59	25	in	in	IN
cord-023443-pvz7dll9	59	26	DA	DA	NNP
cord-023443-pvz7dll9	59	27	rats	rat	NNS
cord-023443-pvz7dll9	59	28	by	by	IN
cord-023443-pvz7dll9	59	29	immunohistochemistry	immunohistochemistry	NN
cord-023443-pvz7dll9	59	30	and	and	CC
cord-023443-pvz7dll9	59	31	to	to	TO
cord-023443-pvz7dll9	59	32	investigate	investigate	VB
cord-023443-pvz7dll9	59	33	how	how	WRB
cord-023443-pvz7dll9	59	34	immunogenicity	immunogenicity	NN
cord-023443-pvz7dll9	59	35	and	and	CC
cord-023443-pvz7dll9	59	36	arthritogenicity	arthritogenicity	NN
cord-023443-pvz7dll9	59	37	was	be	VBD
cord-023443-pvz7dll9	59	38	affected	affect	VBN
cord-023443-pvz7dll9	59	39	by	by	IN
cord-023443-pvz7dll9	59	40	citrullination	citrullination	NN
cord-023443-pvz7dll9	59	41	of	of	IN
cord-023443-pvz7dll9	59	42	rat	rat	NN
cord-023443-pvz7dll9	59	43	serum	serum	NN
cord-023443-pvz7dll9	59	44	albumin	albumin	NN
cord-023443-pvz7dll9	59	45	(	(	-LRB-
cord-023443-pvz7dll9	59	46	RSA	RSA	NNP
cord-023443-pvz7dll9	59	47	)	)	-RRB-
cord-023443-pvz7dll9	59	48	and	and	CC
cord-023443-pvz7dll9	59	49	collagen	collagen	NN
cord-023443-pvz7dll9	59	50	type	type	NN
cord-023443-pvz7dll9	59	51	II	II	NNP
cord-023443-pvz7dll9	59	52	(	(	-LRB-
cord-023443-pvz7dll9	59	53	CII	CII	NNP
cord-023443-pvz7dll9	59	54	)	)	-RRB-
cord-023443-pvz7dll9	59	55	.	.	.
cord-023443-pvz7dll9	60	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	60	2	results	result	NNS
cord-023443-pvz7dll9	60	3	indicate	indicate	VBP
cord-023443-pvz7dll9	60	4	that	that	IN
cord-023443-pvz7dll9	60	5	citrulline	citrulline	NN
cord-023443-pvz7dll9	60	6	could	could	MD
cord-023443-pvz7dll9	60	7	be	be	VB
cord-023443-pvz7dll9	60	8	detected	detect	VBN
cord-023443-pvz7dll9	60	9	in	in	IN
cord-023443-pvz7dll9	60	10	joints	joint	NNS
cord-023443-pvz7dll9	60	11	of	of	IN
cord-023443-pvz7dll9	60	12	arthritic	arthritic	JJ
cord-023443-pvz7dll9	60	13	animals	animal	NNS
cord-023443-pvz7dll9	60	14	,	,	,
cord-023443-pvz7dll9	60	15	first	first	JJ
cord-023443-pvz7dll9	60	16	appearance	appearance	NN
cord-023443-pvz7dll9	60	17	at	at	IN
cord-023443-pvz7dll9	60	18	the	the	DT
cord-023443-pvz7dll9	60	19	onset	onset	NN
cord-023443-pvz7dll9	60	20	of	of	IN
cord-023443-pvz7dll9	60	21	disease	disease	NN
cord-023443-pvz7dll9	60	22	and	and	CC
cord-023443-pvz7dll9	60	23	increasing	increase	VBG
cord-023443-pvz7dll9	60	24	as	as	IN
cord-023443-pvz7dll9	60	25	disease	disease	NN
cord-023443-pvz7dll9	60	26	progressed	progress	VBD
cord-023443-pvz7dll9	60	27	into	into	IN
cord-023443-pvz7dll9	60	28	a	a	DT
cord-023443-pvz7dll9	60	29	chronic	chronic	JJ
cord-023443-pvz7dll9	60	30	state	state	NN
cord-023443-pvz7dll9	60	31	.	.	.
cord-023443-pvz7dll9	61	1	Unimmunized	unimmunized	JJ
cord-023443-pvz7dll9	61	2	animals	animal	NNS
cord-023443-pvz7dll9	61	3	or	or	CC
cord-023443-pvz7dll9	61	4	time	time	NN
cord-023443-pvz7dll9	61	5	points	point	NNS
cord-023443-pvz7dll9	61	6	before	before	IN
cord-023443-pvz7dll9	61	7	clinical	clinical	JJ
cord-023443-pvz7dll9	61	8	signs	sign	NNS
cord-023443-pvz7dll9	61	9	of	of	IN
cord-023443-pvz7dll9	61	10	arthritis	arthritis	NN
cord-023443-pvz7dll9	61	11	were	be	VBD
cord-023443-pvz7dll9	61	12	negative	negative	JJ
cord-023443-pvz7dll9	61	13	.	.	.
cord-023443-pvz7dll9	62	1	By	by	IN
cord-023443-pvz7dll9	62	2	morphology	morphology	NN
cord-023443-pvz7dll9	62	3	,	,	,
cord-023443-pvz7dll9	62	4	we	-PRON-	PRP
cord-023443-pvz7dll9	62	5	state	state	VBP
cord-023443-pvz7dll9	62	6	that	that	IN
cord-023443-pvz7dll9	62	7	some	some	DT
cord-023443-pvz7dll9	62	8	infiltrating	infiltrate	VBG
cord-023443-pvz7dll9	62	9	macrophages	macrophage	NNS
cord-023443-pvz7dll9	62	10	as	as	RB
cord-023443-pvz7dll9	62	11	well	well	RB
cord-023443-pvz7dll9	62	12	as	as	IN
cord-023443-pvz7dll9	62	13	the	the	DT
cord-023443-pvz7dll9	62	14	cartilage	cartilage	NN
cord-023443-pvz7dll9	62	15	surface	surface	NN
cord-023443-pvz7dll9	62	16	stain	stain	NN
cord-023443-pvz7dll9	62	17	positive	positive	JJ
cord-023443-pvz7dll9	62	18	for	for	IN
cord-023443-pvz7dll9	62	19	citrulline	citrulline	NN
cord-023443-pvz7dll9	62	20	,	,	,
cord-023443-pvz7dll9	62	21	while	while	IN
cord-023443-pvz7dll9	62	22	the	the	DT
cord-023443-pvz7dll9	62	23	major	major	JJ
cord-023443-pvz7dll9	62	24	source	source	NN
cord-023443-pvz7dll9	62	25	of	of	IN
cord-023443-pvz7dll9	62	26	citrullinated	citrullinate	VBN
cord-023443-pvz7dll9	62	27	proteins	protein	NNS
cord-023443-pvz7dll9	62	28	appears	appear	VBZ
cord-023443-pvz7dll9	62	29	to	to	TO
cord-023443-pvz7dll9	62	30	be	be	VB
cord-023443-pvz7dll9	62	31	fibrin	fibrin	NN
cord-023443-pvz7dll9	62	32	depositions	deposition	NNS
cord-023443-pvz7dll9	62	33	.	.	.
cord-023443-pvz7dll9	63	1	A	a	DT
cord-023443-pvz7dll9	63	2	specific	specific	JJ
cord-023443-pvz7dll9	63	3	Cit	Cit	NNP
cord-023443-pvz7dll9	63	4	-	-	HYPH
cord-023443-pvz7dll9	63	5	RSA	RSA	NNP
cord-023443-pvz7dll9	63	6	T	t	NN
cord-023443-pvz7dll9	63	7	-	-	HYPH
cord-023443-pvz7dll9	63	8	cell	cell	NN
cord-023443-pvz7dll9	63	9	response	response	NN
cord-023443-pvz7dll9	63	10	was	be	VBD
cord-023443-pvz7dll9	63	11	observed	observe	VBN
cord-023443-pvz7dll9	63	12	in	in	IN
cord-023443-pvz7dll9	63	13	animals	animal	NNS
cord-023443-pvz7dll9	63	14	challenged	challenge	VBN
cord-023443-pvz7dll9	63	15	by	by	IN
cord-023443-pvz7dll9	63	16	citrullinated	citrullinate	VBN
cord-023443-pvz7dll9	63	17	RSA	RSA	NNP
cord-023443-pvz7dll9	63	18	,	,	,
cord-023443-pvz7dll9	63	19	no	no	DT
cord-023443-pvz7dll9	63	20	response	response	NN
cord-023443-pvz7dll9	63	21	was	be	VBD
cord-023443-pvz7dll9	63	22	recorded	record	VBN
cord-023443-pvz7dll9	63	23	when	when	WRB
cord-023443-pvz7dll9	63	24	RSA	RSA	NNP
cord-023443-pvz7dll9	63	25	was	be	VBD
cord-023443-pvz7dll9	63	26	used	use	VBN
cord-023443-pvz7dll9	63	27	as	as	IN
cord-023443-pvz7dll9	63	28	a	a	DT
cord-023443-pvz7dll9	63	29	stimulus	stimulus	NN
cord-023443-pvz7dll9	63	30	.	.	.
cord-023443-pvz7dll9	64	1	The	the	DT
cord-023443-pvz7dll9	64	2	IgG	igg	NN
cord-023443-pvz7dll9	64	3	analysis	analysis	NN
cord-023443-pvz7dll9	64	4	reveals	reveal	VBZ
cord-023443-pvz7dll9	64	5	not	not	RB
cord-023443-pvz7dll9	64	6	only	only	RB
cord-023443-pvz7dll9	64	7	a	a	DT
cord-023443-pvz7dll9	64	8	response	response	NN
cord-023443-pvz7dll9	64	9	towards	towards	IN
cord-023443-pvz7dll9	64	10	the	the	DT
cord-023443-pvz7dll9	64	11	modified	modify	VBN
cord-023443-pvz7dll9	64	12	protein	protein	NN
cord-023443-pvz7dll9	64	13	but	but	CC
cord-023443-pvz7dll9	64	14	also	also	RB
cord-023443-pvz7dll9	64	15	cross	cross	NN
cord-023443-pvz7dll9	64	16	-	-	NN
cord-023443-pvz7dll9	64	17	reactivity	reactivity	NN
cord-023443-pvz7dll9	64	18	to	to	IN
cord-023443-pvz7dll9	64	19	native	native	JJ
cord-023443-pvz7dll9	64	20	RSA	RSA	NNP
cord-023443-pvz7dll9	64	21	.	.	.
cord-023443-pvz7dll9	65	1	No	no	DT
cord-023443-pvz7dll9	65	2	T	t	NN
cord-023443-pvz7dll9	65	3	-	-	HYPH
cord-023443-pvz7dll9	65	4	cell	cell	NN
cord-023443-pvz7dll9	65	5	or	or	CC
cord-023443-pvz7dll9	65	6	B	b	NN
cord-023443-pvz7dll9	65	7	-	-	HYPH
cord-023443-pvz7dll9	65	8	cell	cell	NN
cord-023443-pvz7dll9	65	9	response	response	NN
cord-023443-pvz7dll9	65	10	was	be	VBD
cord-023443-pvz7dll9	65	11	noted	note	VBN
cord-023443-pvz7dll9	65	12	in	in	IN
cord-023443-pvz7dll9	65	13	animals	animal	NNS
cord-023443-pvz7dll9	65	14	injected	inject	VBN
cord-023443-pvz7dll9	65	15	with	with	IN
cord-023443-pvz7dll9	65	16	unmodified	unmodified	JJ
cord-023443-pvz7dll9	65	17	RSA	rsa	NN
cord-023443-pvz7dll9	65	18	.	.	.
cord-023443-pvz7dll9	66	1	Cit	Cit	NNP
cord-023443-pvz7dll9	66	2	-	-	HYPH
cord-023443-pvz7dll9	66	3	CII	CII	NNP
cord-023443-pvz7dll9	66	4	induced	induce	VBD
cord-023443-pvz7dll9	66	5	a	a	DT
cord-023443-pvz7dll9	66	6	disease	disease	NN
cord-023443-pvz7dll9	66	7	with	with	IN
cord-023443-pvz7dll9	66	8	higher	high	JJR
cord-023443-pvz7dll9	66	9	incidence	incidence	NN
cord-023443-pvz7dll9	66	10	and	and	CC
cord-023443-pvz7dll9	66	11	earlier	early	JJR
cord-023443-pvz7dll9	66	12	onset	onset	NN
cord-023443-pvz7dll9	66	13	than	than	IN
cord-023443-pvz7dll9	66	14	did	do	VBD
cord-023443-pvz7dll9	66	15	the	the	DT
cord-023443-pvz7dll9	66	16	native	native	JJ
cord-023443-pvz7dll9	66	17	counterpart	counterpart	NN
cord-023443-pvz7dll9	66	18	.	.	.
cord-023443-pvz7dll9	67	1	We	-PRON-	PRP
cord-023443-pvz7dll9	67	2	conclude	conclude	VBP
cord-023443-pvz7dll9	67	3	that	that	IN
cord-023443-pvz7dll9	67	4	,	,	,
cord-023443-pvz7dll9	67	5	in	in	IN
cord-023443-pvz7dll9	67	6	contrast	contrast	NN
cord-023443-pvz7dll9	67	7	to	to	IN
cord-023443-pvz7dll9	67	8	the	the	DT
cord-023443-pvz7dll9	67	9	human	human	JJ
cord-023443-pvz7dll9	67	10	disease	disease	NN
cord-023443-pvz7dll9	67	11	,	,	,
cord-023443-pvz7dll9	67	12	citrulline	citrulline	NN
cord-023443-pvz7dll9	67	13	does	do	VBZ
cord-023443-pvz7dll9	67	14	not	not	RB
cord-023443-pvz7dll9	67	15	seem	seem	VB
cord-023443-pvz7dll9	67	16	to	to	TO
cord-023443-pvz7dll9	67	17	appear	appear	VB
cord-023443-pvz7dll9	67	18	before	before	IN
cord-023443-pvz7dll9	67	19	clinical	clinical	JJ
cord-023443-pvz7dll9	67	20	signs	sign	NNS
cord-023443-pvz7dll9	67	21	.	.	.
cord-023443-pvz7dll9	68	1	As	as	IN
cord-023443-pvz7dll9	68	2	inflammation	inflammation	NN
cord-023443-pvz7dll9	68	3	proceeds	proceed	NNS
cord-023443-pvz7dll9	68	4	,	,	,
cord-023443-pvz7dll9	68	5	citrulline	citrulline	NN
cord-023443-pvz7dll9	68	6	is	be	VBZ
cord-023443-pvz7dll9	68	7	detected	detect	VBN
cord-023443-pvz7dll9	68	8	specifically	specifically	RB
cord-023443-pvz7dll9	68	9	in	in	IN
cord-023443-pvz7dll9	68	10	the	the	DT
cord-023443-pvz7dll9	68	11	joints	joint	NNS
cord-023443-pvz7dll9	68	12	.	.	.
cord-023443-pvz7dll9	69	1	All	all	DT
cord-023443-pvz7dll9	69	2	other	other	JJ
cord-023443-pvz7dll9	69	3	organs	organ	NNS
cord-023443-pvz7dll9	69	4	investigated	investigate	VBN
cord-023443-pvz7dll9	69	5	were	be	VBD
cord-023443-pvz7dll9	69	6	negative	negative	JJ
cord-023443-pvz7dll9	69	7	.	.	.
cord-023443-pvz7dll9	70	1	We	-PRON-	PRP
cord-023443-pvz7dll9	70	2	also	also	RB
cord-023443-pvz7dll9	70	3	conclude	conclude	VBP
cord-023443-pvz7dll9	70	4	that	that	IN
cord-023443-pvz7dll9	70	5	citrullination	citrullination	NN
cord-023443-pvz7dll9	70	6	of	of	IN
cord-023443-pvz7dll9	70	7	a	a	DT
cord-023443-pvz7dll9	70	8	protein	protein	NN
cord-023443-pvz7dll9	70	9	can	can	MD
cord-023443-pvz7dll9	70	10	break	break	VB
cord-023443-pvz7dll9	70	11	tolerance	tolerance	NN
cord-023443-pvz7dll9	70	12	and	and	CC
cord-023443-pvz7dll9	70	13	increase	increase	VB
cord-023443-pvz7dll9	70	14	its	-PRON-	PRP$
cord-023443-pvz7dll9	70	15	arthritogenic	arthritogenic	JJ
cord-023443-pvz7dll9	70	16	properties	property	NNS
cord-023443-pvz7dll9	70	17	.	.	.
cord-023443-pvz7dll9	71	1	Ectopic	ectopic	JJ
cord-023443-pvz7dll9	71	2	germinal	germinal	JJ
cord-023443-pvz7dll9	71	3	centers	center	NNS
cord-023443-pvz7dll9	71	4	(	(	-LRB-
cord-023443-pvz7dll9	71	5	GCs	GCs	NNP
cord-023443-pvz7dll9	71	6	)	)	-RRB-
cord-023443-pvz7dll9	71	7	can	can	MD
cord-023443-pvz7dll9	71	8	be	be	VB
cord-023443-pvz7dll9	71	9	detected	detect	VBN
cord-023443-pvz7dll9	71	10	in	in	IN
cord-023443-pvz7dll9	71	11	the	the	DT
cord-023443-pvz7dll9	71	12	salivary	salivary	JJ
cord-023443-pvz7dll9	71	13	glands	gland	NNS
cord-023443-pvz7dll9	71	14	of	of	IN
cord-023443-pvz7dll9	71	15	approximately	approximately	RB
cord-023443-pvz7dll9	71	16	1/5	1/5	CD
cord-023443-pvz7dll9	71	17	of	of	IN
cord-023443-pvz7dll9	71	18	patients	patient	NNS
cord-023443-pvz7dll9	71	19	with	with	IN
cord-023443-pvz7dll9	71	20	Sjögren	Sjögren	NNP
cord-023443-pvz7dll9	71	21	's	's	POS
cord-023443-pvz7dll9	71	22	syndrome	syndrome	NN
cord-023443-pvz7dll9	71	23	(	(	-LRB-
cord-023443-pvz7dll9	71	24	SS	SS	NNP
cord-023443-pvz7dll9	71	25	)	)	-RRB-
cord-023443-pvz7dll9	71	26	and	and	CC
cord-023443-pvz7dll9	71	27	appear	appear	VB
cord-023443-pvz7dll9	71	28	in	in	IN
cord-023443-pvz7dll9	71	29	both	both	DT
cord-023443-pvz7dll9	71	30	primary	primary	JJ
cord-023443-pvz7dll9	71	31	and	and	CC
cord-023443-pvz7dll9	71	32	secondary	secondary	JJ
cord-023443-pvz7dll9	71	33	SS	ss	NN
cord-023443-pvz7dll9	71	34	.	.	.
cord-023443-pvz7dll9	72	1	Previously	previously	RB
cord-023443-pvz7dll9	72	2	,	,	,
cord-023443-pvz7dll9	72	3	ectopic	ectopic	JJ
cord-023443-pvz7dll9	72	4	GC	GC	NNP
cord-023443-pvz7dll9	72	5	have	have	VBP
cord-023443-pvz7dll9	72	6	been	be	VBN
cord-023443-pvz7dll9	72	7	associated	associate	VBN
cord-023443-pvz7dll9	72	8	with	with	IN
cord-023443-pvz7dll9	72	9	increased	increase	VBN
cord-023443-pvz7dll9	72	10	local	local	JJ
cord-023443-pvz7dll9	72	11	autoantibody	autoantibody	NN
cord-023443-pvz7dll9	72	12	production	production	NN
cord-023443-pvz7dll9	72	13	.	.	.
cord-023443-pvz7dll9	73	1	The	the	DT
cord-023443-pvz7dll9	73	2	aim	aim	NN
cord-023443-pvz7dll9	73	3	of	of	IN
cord-023443-pvz7dll9	73	4	this	this	DT
cord-023443-pvz7dll9	73	5	study	study	NN
cord-023443-pvz7dll9	73	6	was	be	VBD
cord-023443-pvz7dll9	73	7	to	to	TO
cord-023443-pvz7dll9	73	8	determine	determine	VB
cord-023443-pvz7dll9	73	9	whether	whether	IN
cord-023443-pvz7dll9	73	10	GC	GC	NNP
cord-023443-pvz7dll9	73	11	in	in	IN
cord-023443-pvz7dll9	73	12	primary	primary	JJ
cord-023443-pvz7dll9	73	13	Sjögren	Sjögren	NNP
cord-023443-pvz7dll9	73	14	's	's	POS
cord-023443-pvz7dll9	73	15	syndrome	syndrome	NN
cord-023443-pvz7dll9	73	16	(	(	-LRB-
cord-023443-pvz7dll9	73	17	pSS	pSS	NNP
cord-023443-pvz7dll9	73	18	)	)	-RRB-
cord-023443-pvz7dll9	73	19	defines	define	VBZ
cord-023443-pvz7dll9	73	20	a	a	DT
cord-023443-pvz7dll9	73	21	distinct	distinct	JJ
cord-023443-pvz7dll9	73	22	seroimmunological	seroimmunological	JJ
cord-023443-pvz7dll9	73	23	phenotype	phenotype	NN
cord-023443-pvz7dll9	73	24	.	.	.
cord-023443-pvz7dll9	74	1	Retrospectively	retrospectively	RB
cord-023443-pvz7dll9	74	2	,	,	,
cord-023443-pvz7dll9	74	3	a	a	DT
cord-023443-pvz7dll9	74	4	material	material	NN
cord-023443-pvz7dll9	74	5	of	of	IN
cord-023443-pvz7dll9	74	6	130	130	CD
cord-023443-pvz7dll9	74	7	haematoxylin	haematoxylin	NN
cord-023443-pvz7dll9	74	8	and	and	CC
cord-023443-pvz7dll9	74	9	eosin	eosin	NN
cord-023443-pvz7dll9	74	10	-	-	HYPH
cord-023443-pvz7dll9	74	11	stained	stain	VBN
cord-023443-pvz7dll9	74	12	paraffin	paraffin	NN
cord-023443-pvz7dll9	74	13	-	-	HYPH
cord-023443-pvz7dll9	74	14	embedded	embed	VBN
cord-023443-pvz7dll9	74	15	tissue	tissue	NN
cord-023443-pvz7dll9	74	16	sections	section	NNS
cord-023443-pvz7dll9	74	17	of	of	IN
cord-023443-pvz7dll9	74	18	minor	minor	JJ
cord-023443-pvz7dll9	74	19	salivary	salivary	NN
cord-023443-pvz7dll9	74	20	gland	gland	NN
cord-023443-pvz7dll9	74	21	tissue	tissue	NN
cord-023443-pvz7dll9	74	22	from	from	IN
cord-023443-pvz7dll9	74	23	patients	patient	NNS
cord-023443-pvz7dll9	74	24	with	with	IN
cord-023443-pvz7dll9	74	25	pSS	pSS	NNP
cord-023443-pvz7dll9	74	26	was	be	VBD
cord-023443-pvz7dll9	74	27	morphologically	morphologically	RB
cord-023443-pvz7dll9	74	28	screened	screen	VBN
cord-023443-pvz7dll9	74	29	for	for	IN
cord-023443-pvz7dll9	74	30	the	the	DT
cord-023443-pvz7dll9	74	31	presence	presence	NN
cord-023443-pvz7dll9	74	32	of	of	IN
cord-023443-pvz7dll9	74	33	ectopic	ectopic	JJ
cord-023443-pvz7dll9	74	34	GC	GC	NNP
cord-023443-pvz7dll9	74	35	.	.	.
cord-023443-pvz7dll9	75	1	GC	GC	NNP
cord-023443-pvz7dll9	75	2	-	-	HYPH
cord-023443-pvz7dll9	75	3	like	like	JJ
cord-023443-pvz7dll9	75	4	lesions	lesion	NNS
cord-023443-pvz7dll9	75	5	were	be	VBD
cord-023443-pvz7dll9	75	6	detected	detect	VBN
cord-023443-pvz7dll9	75	7	in	in	IN
cord-023443-pvz7dll9	75	8	33/130	33/130	CD
cord-023443-pvz7dll9	75	9	(	(	-LRB-
cord-023443-pvz7dll9	75	10	25	25	CD
cord-023443-pvz7dll9	75	11	%	%	NN
cord-023443-pvz7dll9	75	12	)	)	-RRB-
cord-023443-pvz7dll9	75	13	of	of	IN
cord-023443-pvz7dll9	75	14	the	the	DT
cord-023443-pvz7dll9	75	15	pSS	pSS	NNP
cord-023443-pvz7dll9	75	16	patients	patient	NNS
cord-023443-pvz7dll9	75	17	.	.	.
cord-023443-pvz7dll9	76	1	Seventy	seventy	CD
cord-023443-pvz7dll9	76	2	-	-	HYPH
cord-023443-pvz7dll9	76	3	two	two	CD
cord-023443-pvz7dll9	76	4	pSS	ps	NNS
cord-023443-pvz7dll9	76	5	patients	patient	NNS
cord-023443-pvz7dll9	76	6	lacking	lack	VBG
cord-023443-pvz7dll9	76	7	these	these	DT
cord-023443-pvz7dll9	76	8	structures	structure	NNS
cord-023443-pvz7dll9	76	9	(	(	-LRB-
cord-023443-pvz7dll9	76	10	GC-	GC-	NNP
cord-023443-pvz7dll9	76	11	)	)	-RRB-
cord-023443-pvz7dll9	76	12	were	be	VBD
cord-023443-pvz7dll9	76	13	randomly	randomly	RB
cord-023443-pvz7dll9	76	14	selected	select	VBN
cord-023443-pvz7dll9	76	15	for	for	IN
cord-023443-pvz7dll9	76	16	comparison	comparison	NN
cord-023443-pvz7dll9	76	17	.	.	.
cord-023443-pvz7dll9	77	1	Focus	focus	JJ
cord-023443-pvz7dll9	77	2	score	score	NN
cord-023443-pvz7dll9	77	3	was	be	VBD
cord-023443-pvz7dll9	77	4	significantly	significantly	RB
cord-023443-pvz7dll9	77	5	increased	increase	VBN
cord-023443-pvz7dll9	77	6	in	in	IN
cord-023443-pvz7dll9	77	7	the	the	DT
cord-023443-pvz7dll9	77	8	GC	GC	NNP
cord-023443-pvz7dll9	77	9	þ	þ	CD
cord-023443-pvz7dll9	77	10	patients	patient	NNS
cord-023443-pvz7dll9	77	11	compared	compare	VBN
cord-023443-pvz7dll9	77	12	to	to	IN
cord-023443-pvz7dll9	77	13	the	the	DT
cord-023443-pvz7dll9	77	14	GCpatients	GCpatients	NNP
cord-023443-pvz7dll9	78	1	(	(	-LRB-
cord-023443-pvz7dll9	78	2	P	p	NN
cord-023443-pvz7dll9	78	3	¼	¼	CD
cord-023443-pvz7dll9	78	4	0.035	0.035	CD
cord-023443-pvz7dll9	78	5	)	)	-RRB-
cord-023443-pvz7dll9	78	6	.	.	.
cord-023443-pvz7dll9	79	1	In	in	IN
cord-023443-pvz7dll9	79	2	the	the	DT
cord-023443-pvz7dll9	79	3	GC	GC	NNP
cord-023443-pvz7dll9	79	4	þ	þ	NNP
cord-023443-pvz7dll9	79	5	group	group	NN
cord-023443-pvz7dll9	79	6	,	,	,
cord-023443-pvz7dll9	79	7	54.5	54.5	CD
cord-023443-pvz7dll9	79	8	%	%	NN
cord-023443-pvz7dll9	79	9	of	of	IN
cord-023443-pvz7dll9	79	10	the	the	DT
cord-023443-pvz7dll9	79	11	patients	patient	NNS
cord-023443-pvz7dll9	79	12	presented	present	VBN
cord-023443-pvz7dll9	79	13	with	with	IN
cord-023443-pvz7dll9	79	14	anti	anti	JJ
cord-023443-pvz7dll9	79	15	-	-	JJ
cord-023443-pvz7dll9	79	16	Ro	ro	JJ
cord-023443-pvz7dll9	79	17	/	/	SYM
cord-023443-pvz7dll9	79	18	SSA	SSA	NNP
cord-023443-pvz7dll9	79	19	compared	compare	VBN
cord-023443-pvz7dll9	79	20	to	to	IN
cord-023443-pvz7dll9	79	21	43.7	43.7	CD
cord-023443-pvz7dll9	79	22	%	%	NN
cord-023443-pvz7dll9	79	23	in	in	IN
cord-023443-pvz7dll9	79	24	the	the	DT
cord-023443-pvz7dll9	79	25	GCgroup	GCgroup	NNP
cord-023443-pvz7dll9	79	26	.	.	.
cord-023443-pvz7dll9	80	1	Anti	Anti	NNP
cord-023443-pvz7dll9	80	2	-	-	NNP
cord-023443-pvz7dll9	80	3	La	La	NNP
cord-023443-pvz7dll9	80	4	/	/	SYM
cord-023443-pvz7dll9	80	5	SSB	SSB	NNP
cord-023443-pvz7dll9	80	6	was	be	VBD
cord-023443-pvz7dll9	80	7	detected	detect	VBN
cord-023443-pvz7dll9	80	8	in	in	IN
cord-023443-pvz7dll9	80	9	31.3	31.3	CD
cord-023443-pvz7dll9	80	10	%	%	NN
cord-023443-pvz7dll9	80	11	of	of	IN
cord-023443-pvz7dll9	80	12	the	the	DT
cord-023443-pvz7dll9	80	13	GC	GC	NNP
cord-023443-pvz7dll9	80	14	þ	þ	CD
cord-023443-pvz7dll9	80	15	patients	patient	NNS
cord-023443-pvz7dll9	80	16	compared	compare	VBN
cord-023443-pvz7dll9	80	17	to	to	IN
cord-023443-pvz7dll9	80	18	25.7	25.7	CD
cord-023443-pvz7dll9	80	19	%	%	NN
cord-023443-pvz7dll9	80	20	of	of	IN
cord-023443-pvz7dll9	80	21	the	the	DT
cord-023443-pvz7dll9	80	22	GCpatients	GCpatients	NNP
cord-023443-pvz7dll9	80	23	.	.	.
cord-023443-pvz7dll9	81	1	Sixty	sixty	CD
cord-023443-pvz7dll9	81	2	-	-	HYPH
cord-023443-pvz7dll9	81	3	one	one	CD
cord-023443-pvz7dll9	81	4	percentage	percentage	NN
cord-023443-pvz7dll9	81	5	of	of	IN
cord-023443-pvz7dll9	81	6	GC	GC	NNP
cord-023443-pvz7dll9	81	7	þ	þ	NNP
cord-023443-pvz7dll9	81	8	patients	patient	NNS
cord-023443-pvz7dll9	81	9	presented	present	VBN
cord-023443-pvz7dll9	81	10	with	with	IN
cord-023443-pvz7dll9	81	11	increased	increase	VBN
cord-023443-pvz7dll9	81	12	levels	level	NNS
cord-023443-pvz7dll9	81	13	of	of	IN
cord-023443-pvz7dll9	81	14	IgG	IgG	NNP
cord-023443-pvz7dll9	81	15	,	,	,
cord-023443-pvz7dll9	81	16	a	a	DT
cord-023443-pvz7dll9	81	17	nonsignificant	nonsignificant	JJ
cord-023443-pvz7dll9	81	18	difference	difference	NN
cord-023443-pvz7dll9	81	19	when	when	WRB
cord-023443-pvz7dll9	81	20	compared	compare	VBN
cord-023443-pvz7dll9	81	21	to	to	IN
cord-023443-pvz7dll9	81	22	39.4	39.4	CD
cord-023443-pvz7dll9	81	23	%	%	NN
cord-023443-pvz7dll9	81	24	in	in	IN
cord-023443-pvz7dll9	81	25	the	the	DT
cord-023443-pvz7dll9	81	26	GCpatients	GCpatients	NNP
cord-023443-pvz7dll9	82	1	(	(	-LRB-
cord-023443-pvz7dll9	82	2	P	p	NN
cord-023443-pvz7dll9	82	3	¼	¼	NNP
cord-023443-pvz7dll9	82	4	0.089	0.089	CD
cord-023443-pvz7dll9	82	5	)	)	-RRB-
cord-023443-pvz7dll9	82	6	.	.	.
cord-023443-pvz7dll9	83	1	Levels	level	NNS
cord-023443-pvz7dll9	83	2	of	of	IN
cord-023443-pvz7dll9	83	3	RF	RF	NNP
cord-023443-pvz7dll9	83	4	,	,	,
cord-023443-pvz7dll9	83	5	ANA	ANA	NNP
cord-023443-pvz7dll9	83	6	,	,	,
cord-023443-pvz7dll9	83	7	ENA	ENA	NNP
cord-023443-pvz7dll9	83	8	,	,	,
cord-023443-pvz7dll9	83	9	IgM	IgM	NNP
cord-023443-pvz7dll9	83	10	and	and	CC
cord-023443-pvz7dll9	83	11	IgA	IgA	NNP
cord-023443-pvz7dll9	83	12	were	be	VBD
cord-023443-pvz7dll9	83	13	similar	similar	JJ
cord-023443-pvz7dll9	83	14	in	in	IN
cord-023443-pvz7dll9	83	15	both	both	DT
cord-023443-pvz7dll9	83	16	patient	patient	JJ
cord-023443-pvz7dll9	83	17	groups	group	NNS
cord-023443-pvz7dll9	83	18	,	,	,
cord-023443-pvz7dll9	83	19	as	as	IN
cord-023443-pvz7dll9	83	20	were	be	VBD
cord-023443-pvz7dll9	83	21	ESR	ESR	NNP
cord-023443-pvz7dll9	83	22	and	and	CC
cord-023443-pvz7dll9	83	23	CRP	CRP	NNP
cord-023443-pvz7dll9	83	24	.	.	.
cord-023443-pvz7dll9	84	1	In	in	IN
cord-023443-pvz7dll9	84	2	conclusion	conclusion	NN
cord-023443-pvz7dll9	84	3	,	,	,
cord-023443-pvz7dll9	84	4	patients	patient	NNS
cord-023443-pvz7dll9	84	5	with	with	IN
cord-023443-pvz7dll9	84	6	ectopic	ectopic	JJ
cord-023443-pvz7dll9	84	7	GC	GC	NNP
cord-023443-pvz7dll9	84	8	have	have	VBP
cord-023443-pvz7dll9	84	9	a	a	DT
cord-023443-pvz7dll9	84	10	higher	high	JJR
cord-023443-pvz7dll9	84	11	focus	focus	NN
cord-023443-pvz7dll9	84	12	score	score	NN
cord-023443-pvz7dll9	84	13	and	and	CC
cord-023443-pvz7dll9	84	14	more	more	RBR
cord-023443-pvz7dll9	84	15	often	often	RB
cord-023443-pvz7dll9	84	16	present	present	JJ
cord-023443-pvz7dll9	84	17	with	with	IN
cord-023443-pvz7dll9	84	18	autoantibodies	autoantibody	NNS
cord-023443-pvz7dll9	84	19	and	and	CC
cord-023443-pvz7dll9	84	20	increased	increase	VBN
cord-023443-pvz7dll9	84	21	levels	level	NNS
cord-023443-pvz7dll9	84	22	of	of	IN
cord-023443-pvz7dll9	84	23	IgG	igg	NN
cord-023443-pvz7dll9	84	24	compared	compare	VBN
cord-023443-pvz7dll9	84	25	to	to	IN
cord-023443-pvz7dll9	84	26	pSS	pSS	NNP
cord-023443-pvz7dll9	84	27	patients	patient	NNS
cord-023443-pvz7dll9	84	28	with	with	IN
cord-023443-pvz7dll9	84	29	regular	regular	JJ
cord-023443-pvz7dll9	84	30	focal	focal	JJ
cord-023443-pvz7dll9	84	31	infiltration	infiltration	NN
cord-023443-pvz7dll9	84	32	(	(	-LRB-
cord-023443-pvz7dll9	84	33	GC	GC	NNP
cord-023443-pvz7dll9	84	34	-	-	,
cord-023443-pvz7dll9	84	35	)	)	-RRB-
cord-023443-pvz7dll9	84	36	.	.	.
cord-023443-pvz7dll9	85	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	85	2	findings	finding	NNS
cord-023443-pvz7dll9	85	3	may	may	MD
cord-023443-pvz7dll9	85	4	indicate	indicate	VB
cord-023443-pvz7dll9	85	5	a	a	DT
cord-023443-pvz7dll9	85	6	certain	certain	JJ
cord-023443-pvz7dll9	85	7	seroimmunological	seroimmunological	JJ
cord-023443-pvz7dll9	85	8	phenotype	phenotype	NN
cord-023443-pvz7dll9	85	9	and	and	CC
cord-023443-pvz7dll9	85	10	warrant	warrant	VB
cord-023443-pvz7dll9	85	11	for	for	IN
cord-023443-pvz7dll9	85	12	further	further	JJ
cord-023443-pvz7dll9	85	13	prospective	prospective	JJ
cord-023443-pvz7dll9	85	14	studies	study	NNS
cord-023443-pvz7dll9	85	15	.	.	.
cord-023443-pvz7dll9	86	1	Association	association	NN
cord-023443-pvz7dll9	86	2	between	between	IN
cord-023443-pvz7dll9	86	3	Mannose	Mannose	NNP
cord-023443-pvz7dll9	86	4	-	-	HYPH
cord-023443-pvz7dll9	86	5	Binding	bind	VBG
cord-023443-pvz7dll9	86	6	Lectin	Lectin	NNP
cord-023443-pvz7dll9	86	7	and	and	CC
cord-023443-pvz7dll9	86	8	Vascular	Vascular	NNP
cord-023443-pvz7dll9	86	9	Complications	Complications	NNPS
cord-023443-pvz7dll9	86	10	in	in	IN
cord-023443-pvz7dll9	86	11	Type	type	NN
cord-023443-pvz7dll9	86	12	1	1	CD
cord-023443-pvz7dll9	86	13	Diabetes	diabetes	NN
cord-023443-pvz7dll9	86	14	Complement	Complement	NNP
cord-023443-pvz7dll9	86	15	activation	activation	NN
cord-023443-pvz7dll9	86	16	and	and	CC
cord-023443-pvz7dll9	86	17	inflammation	inflammation	NN
cord-023443-pvz7dll9	86	18	have	have	VBP
cord-023443-pvz7dll9	86	19	been	be	VBN
cord-023443-pvz7dll9	86	20	suggested	suggest	VBN
cord-023443-pvz7dll9	86	21	in	in	IN
cord-023443-pvz7dll9	86	22	the	the	DT
cord-023443-pvz7dll9	86	23	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	86	24	of	of	IN
cord-023443-pvz7dll9	86	25	diabetic	diabetic	JJ
cord-023443-pvz7dll9	86	26	vascular	vascular	JJ
cord-023443-pvz7dll9	86	27	lesions	lesion	NNS
cord-023443-pvz7dll9	86	28	.	.	.
cord-023443-pvz7dll9	87	1	We	-PRON-	PRP
cord-023443-pvz7dll9	87	2	investigated	investigate	VBD
cord-023443-pvz7dll9	87	3	serum	serum	NN
cord-023443-pvz7dll9	87	4	mannose	mannose	NN
cord-023443-pvz7dll9	87	5	-	-	HYPH
cord-023443-pvz7dll9	87	6	binding	bind	VBG
cord-023443-pvz7dll9	87	7	lectin	lectin	NN
cord-023443-pvz7dll9	87	8	(	(	-LRB-
cord-023443-pvz7dll9	87	9	MBL	MBL	NNP
cord-023443-pvz7dll9	87	10	)	)	-RRB-
cord-023443-pvz7dll9	87	11	levels	level	NNS
cord-023443-pvz7dll9	87	12	and	and	CC
cord-023443-pvz7dll9	87	13	polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	87	14	in	in	IN
cord-023443-pvz7dll9	87	15	the	the	DT
cord-023443-pvz7dll9	87	16	MBL	MBL	NNP
cord-023443-pvz7dll9	87	17	gene	gene	NN
cord-023443-pvz7dll9	87	18	in	in	IN
cord-023443-pvz7dll9	87	19	type	type	NN
cord-023443-pvz7dll9	87	20	1	1	CD
cord-023443-pvz7dll9	87	21	diabetic	diabetic	JJ
cord-023443-pvz7dll9	87	22	(	(	-LRB-
cord-023443-pvz7dll9	87	23	T1DM	T1DM	NNP
cord-023443-pvz7dll9	87	24	)	)	-RRB-
cord-023443-pvz7dll9	87	25	patients	patient	NNS
cord-023443-pvz7dll9	87	26	with	with	IN
cord-023443-pvz7dll9	87	27	and	and	CC
cord-023443-pvz7dll9	87	28	without	without	IN
cord-023443-pvz7dll9	87	29	diabetic	diabetic	JJ
cord-023443-pvz7dll9	87	30	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	87	31	and	and	CC
cord-023443-pvz7dll9	87	32	associated	associate	VBD
cord-023443-pvz7dll9	87	33	macrovascular	macrovascular	JJ
cord-023443-pvz7dll9	87	34	complications	complication	NNS
cord-023443-pvz7dll9	87	35	.	.	.
cord-023443-pvz7dll9	88	1	Polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	88	2	in	in	IN
cord-023443-pvz7dll9	88	3	the	the	DT
cord-023443-pvz7dll9	88	4	MBL	MBL	NNP
cord-023443-pvz7dll9	88	5	gene	gene	NN
cord-023443-pvz7dll9	88	6	and	and	CC
cord-023443-pvz7dll9	88	7	serum	serum	NN
cord-023443-pvz7dll9	88	8	MBL	MBL	NNP
cord-023443-pvz7dll9	88	9	levels	level	NNS
cord-023443-pvz7dll9	88	10	were	be	VBD
cord-023443-pvz7dll9	88	11	determined	determine	VBN
cord-023443-pvz7dll9	88	12	in	in	IN
cord-023443-pvz7dll9	88	13	199	199	CD
cord-023443-pvz7dll9	88	14	T1DM	T1DM	NNP
cord-023443-pvz7dll9	88	15	patients	patient	NNS
cord-023443-pvz7dll9	88	16	with	with	IN
cord-023443-pvz7dll9	88	17	overt	overt	JJ
cord-023443-pvz7dll9	88	18	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	88	19	and	and	CC
cord-023443-pvz7dll9	88	20	192	192	CD
cord-023443-pvz7dll9	88	21	T1DM	T1DM	NNP
cord-023443-pvz7dll9	88	22	patients	patient	NNS
cord-023443-pvz7dll9	88	23	with	with	IN
cord-023443-pvz7dll9	88	24	persistent	persistent	JJ
cord-023443-pvz7dll9	88	25	normoalbuminuria	normoalbuminuria	NNP
cord-023443-pvz7dll9	88	26	matched	match	VBN
cord-023443-pvz7dll9	88	27	for	for	IN
cord-023443-pvz7dll9	88	28	age	age	NN
cord-023443-pvz7dll9	88	29	,	,	,
cord-023443-pvz7dll9	88	30	sex	sex	NN
cord-023443-pvz7dll9	88	31	and	and	CC
cord-023443-pvz7dll9	88	32	duration	duration	NN
cord-023443-pvz7dll9	88	33	of	of	IN
cord-023443-pvz7dll9	88	34	diabetes	diabete	NNS
cord-023443-pvz7dll9	88	35	as	as	RB
cord-023443-pvz7dll9	88	36	well	well	RB
cord-023443-pvz7dll9	88	37	as	as	IN
cord-023443-pvz7dll9	88	38	in	in	IN
cord-023443-pvz7dll9	88	39	100	100	CD
cord-023443-pvz7dll9	88	40	healthy	healthy	JJ
cord-023443-pvz7dll9	88	41	control	control	NN
cord-023443-pvz7dll9	88	42	subjects	subject	NNS
cord-023443-pvz7dll9	88	43	.	.	.
cord-023443-pvz7dll9	89	1	The	the	DT
cord-023443-pvz7dll9	89	2	frequencies	frequency	NNS
cord-023443-pvz7dll9	89	3	of	of	IN
cord-023443-pvz7dll9	89	4	high	high	JJ
cord-023443-pvz7dll9	89	5	and	and	CC
cord-023443-pvz7dll9	89	6	low	low	JJ
cord-023443-pvz7dll9	89	7	expression	expression	NN
cord-023443-pvz7dll9	89	8	MBL	MBL	NNP
cord-023443-pvz7dll9	89	9	genotypes	genotype	NNS
cord-023443-pvz7dll9	89	10	were	be	VBD
cord-023443-pvz7dll9	89	11	similar	similar	JJ
cord-023443-pvz7dll9	89	12	in	in	IN
cord-023443-pvz7dll9	89	13	patients	patient	NNS
cord-023443-pvz7dll9	89	14	with	with	IN
cord-023443-pvz7dll9	89	15	T1DM	t1dm	JJ
cord-023443-pvz7dll9	89	16	and	and	CC
cord-023443-pvz7dll9	89	17	healthy	healthy	JJ
cord-023443-pvz7dll9	89	18	controls	control	NNS
cord-023443-pvz7dll9	89	19	.	.	.
cord-023443-pvz7dll9	90	1	High	high	JJ
cord-023443-pvz7dll9	90	2	MBL	MBL	NNP
cord-023443-pvz7dll9	90	3	genotypes	genotype	NNS
cord-023443-pvz7dll9	90	4	were	be	VBD
cord-023443-pvz7dll9	90	5	significantly	significantly	RB
cord-023443-pvz7dll9	90	6	more	more	RBR
cord-023443-pvz7dll9	90	7	frequent	frequent	JJ
cord-023443-pvz7dll9	90	8	in	in	IN
cord-023443-pvz7dll9	90	9	diabetic	diabetic	JJ
cord-023443-pvz7dll9	90	10	patients	patient	NNS
cord-023443-pvz7dll9	90	11	with	with	IN
cord-023443-pvz7dll9	90	12	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	90	13	than	than	IN
cord-023443-pvz7dll9	90	14	in	in	IN
cord-023443-pvz7dll9	90	15	the	the	DT
cord-023443-pvz7dll9	90	16	normoalbuminuric	normoalbuminuric	NNP
cord-023443-pvz7dll9	90	17	group	group	NN
cord-023443-pvz7dll9	90	18	,	,	,
cord-023443-pvz7dll9	90	19	and	and	CC
cord-023443-pvz7dll9	90	20	the	the	DT
cord-023443-pvz7dll9	90	21	risk	risk	NN
cord-023443-pvz7dll9	90	22	of	of	IN
cord-023443-pvz7dll9	90	23	having	have	VBG
cord-023443-pvz7dll9	90	24	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	90	25	,	,	,
cord-023443-pvz7dll9	90	26	given	give	VBN
cord-023443-pvz7dll9	90	27	a	a	DT
cord-023443-pvz7dll9	90	28	high	high	JJ
cord-023443-pvz7dll9	90	29	MBL	MBL	NNP
cord-023443-pvz7dll9	90	30	genotype	genotype	NN
cord-023443-pvz7dll9	90	31	,	,	,
cord-023443-pvz7dll9	90	32	assessed	assess	VBN
cord-023443-pvz7dll9	90	33	by	by	IN
cord-023443-pvz7dll9	90	34	odds	odd	NNS
cord-023443-pvz7dll9	90	35	ratio	ratio	NN
cord-023443-pvz7dll9	90	36	was	be	VBD
cord-023443-pvz7dll9	90	37	1.52	1.52	CD
cord-023443-pvz7dll9	90	38	(	(	-LRB-
cord-023443-pvz7dll9	90	39	1.02	1.02	CD
cord-023443-pvz7dll9	90	40	-	-	SYM
cord-023443-pvz7dll9	90	41	2.27	2.27	CD
cord-023443-pvz7dll9	90	42	)	)	-RRB-
cord-023443-pvz7dll9	90	43	,	,	,
cord-023443-pvz7dll9	90	44	P	p	NN
cord-023443-pvz7dll9	90	45	¼	¼	CD
cord-023443-pvz7dll9	90	46	0.04	0.04	CD
cord-023443-pvz7dll9	90	47	.	.	.
cord-023443-pvz7dll9	91	1	Median	median	JJ
cord-023443-pvz7dll9	91	2	serum	serum	NN
cord-023443-pvz7dll9	91	3	MBL	MBL	NNP
cord-023443-pvz7dll9	91	4	concentrations	concentration	NNS
cord-023443-pvz7dll9	91	5	were	be	VBD
cord-023443-pvz7dll9	91	6	significantly	significantly	RB
cord-023443-pvz7dll9	91	7	higher	high	JJR
cord-023443-pvz7dll9	91	8	in	in	IN
cord-023443-pvz7dll9	91	9	patients	patient	NNS
cord-023443-pvz7dll9	91	10	with	with	IN
cord-023443-pvz7dll9	91	11	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	91	12	than	than	IN
cord-023443-pvz7dll9	91	13	in	in	IN
cord-023443-pvz7dll9	91	14	patients	patient	NNS
cord-023443-pvz7dll9	91	15	with	with	IN
cord-023443-pvz7dll9	91	16	normoalbuminuria	normoalbuminuria	NNP
cord-023443-pvz7dll9	92	1	[	[	-LRB-
cord-023443-pvz7dll9	92	2	2306	2306	CD
cord-023443-pvz7dll9	92	3	mg	mg	NNP
cord-023443-pvz7dll9	92	4	/	/	SYM
cord-023443-pvz7dll9	92	5	l	l	NN
cord-023443-pvz7dll9	92	6	(	(	-LRB-
cord-023443-pvz7dll9	92	7	IQR	IQR	NNP
cord-023443-pvz7dll9	92	8	753	753	CD
cord-023443-pvz7dll9	92	9	-	-	HYPH
cord-023443-pvz7dll9	92	10	4867	4867	CD
cord-023443-pvz7dll9	92	11	mg	mg	NNP
cord-023443-pvz7dll9	92	12	/	/	SYM
cord-023443-pvz7dll9	92	13	l	l	NNP
cord-023443-pvz7dll9	92	14	)	)	-RRB-
cord-023443-pvz7dll9	92	15	versus	versus	IN
cord-023443-pvz7dll9	92	16	1491	1491	CD
cord-023443-pvz7dll9	92	17	mg	mg	NNP
cord-023443-pvz7dll9	92	18	/	/	SYM
cord-023443-pvz7dll9	92	19	l	l	NN
cord-023443-pvz7dll9	92	20	(	(	-LRB-
cord-023443-pvz7dll9	92	21	IQR	IQR	NNP
cord-023443-pvz7dll9	92	22	577	577	CD
cord-023443-pvz7dll9	92	23	-	-	HYPH
cord-023443-pvz7dll9	92	24	2944	2944	CD
cord-023443-pvz7dll9	92	25	)	)	-RRB-
cord-023443-pvz7dll9	92	26	,	,	,
cord-023443-pvz7dll9	92	27	P	p	NN
cord-023443-pvz7dll9	92	28	¼	¼	CD
cord-023443-pvz7dll9	92	29	0.0003	0.0003	CD
cord-023443-pvz7dll9	92	30	]	]	-RRB-
cord-023443-pvz7dll9	92	31	,	,	,
cord-023443-pvz7dll9	92	32	and	and	CC
cord-023443-pvz7dll9	92	33	even	even	RB
cord-023443-pvz7dll9	92	34	when	when	WRB
cord-023443-pvz7dll9	92	35	comparing	compare	VBG
cord-023443-pvz7dll9	92	36	patients	patient	NNS
cord-023443-pvz7dll9	92	37	with	with	IN
cord-023443-pvz7dll9	92	38	identical	identical	JJ
cord-023443-pvz7dll9	92	39	genotypes	genotype	NNS
cord-023443-pvz7dll9	92	40	,	,	,
cord-023443-pvz7dll9	92	41	serum	serum	NN
cord-023443-pvz7dll9	92	42	MBL	MBL	NNP
cord-023443-pvz7dll9	92	43	levels	level	NNS
cord-023443-pvz7dll9	92	44	were	be	VBD
cord-023443-pvz7dll9	92	45	higher	high	JJR
cord-023443-pvz7dll9	92	46	in	in	IN
cord-023443-pvz7dll9	92	47	the	the	DT
cord-023443-pvz7dll9	92	48	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	92	49	group	group	NN
cord-023443-pvz7dll9	92	50	than	than	IN
cord-023443-pvz7dll9	92	51	in	in	IN
cord-023443-pvz7dll9	92	52	the	the	DT
cord-023443-pvz7dll9	92	53	normoalbuminuric	normoalbuminuric	NNP
cord-023443-pvz7dll9	92	54	group	group	NN
cord-023443-pvz7dll9	92	55	.	.	.
cord-023443-pvz7dll9	93	1	Patients	patient	NNS
cord-023443-pvz7dll9	93	2	with	with	IN
cord-023443-pvz7dll9	93	3	a	a	DT
cord-023443-pvz7dll9	93	4	history	history	NN
cord-023443-pvz7dll9	93	5	of	of	IN
cord-023443-pvz7dll9	93	6	cardiovascular	cardiovascular	JJ
cord-023443-pvz7dll9	93	7	disease	disease	NN
cord-023443-pvz7dll9	93	8	had	have	VBD
cord-023443-pvz7dll9	93	9	significantly	significantly	RB
cord-023443-pvz7dll9	93	10	elevated	elevate	VBN
cord-023443-pvz7dll9	93	11	MBL	MBL	NNP
cord-023443-pvz7dll9	93	12	levels	level	NNS
cord-023443-pvz7dll9	93	13	independently	independently	RB
cord-023443-pvz7dll9	93	14	of	of	IN
cord-023443-pvz7dll9	93	15	nephropathy	nephropathy	NN
cord-023443-pvz7dll9	93	16	status	status	NN
cord-023443-pvz7dll9	93	17	[	[	-LRB-
cord-023443-pvz7dll9	93	18	3178	3178	CD
cord-023443-pvz7dll9	93	19	mg	mg	NNP
cord-023443-pvz7dll9	93	20	/	/	SYM
cord-023443-pvz7dll9	93	21	l	l	NN
cord-023443-pvz7dll9	93	22	(	(	-LRB-
cord-023443-pvz7dll9	93	23	IQR	IQR	NNP
cord-023443-pvz7dll9	93	24	636	636	CD
cord-023443-pvz7dll9	93	25	-	-	HYPH
cord-023443-pvz7dll9	93	26	5231	5231	CD
cord-023443-pvz7dll9	93	27	mg	mg	NNP
cord-023443-pvz7dll9	93	28	/	/	SYM
cord-023443-pvz7dll9	93	29	l	l	NNP
cord-023443-pvz7dll9	93	30	)	)	-RRB-
cord-023443-pvz7dll9	93	31	versus	versus	IN
cord-023443-pvz7dll9	93	32	1741	1741	CD
cord-023443-pvz7dll9	93	33	mg	mg	NNP
cord-023443-pvz7dll9	93	34	/	/	SYM
cord-023443-pvz7dll9	93	35	l	l	NN
cord-023443-pvz7dll9	93	36	(	(	-LRB-
cord-023443-pvz7dll9	93	37	IQR	IQR	NNP
cord-023443-pvz7dll9	93	38	656	656	CD
cord-023443-pvz7dll9	93	39	-	-	HYPH
cord-023443-pvz7dll9	93	40	3149	3149	CD
cord-023443-pvz7dll9	93	41	mg	mg	NNP
cord-023443-pvz7dll9	93	42	/	/	SYM
cord-023443-pvz7dll9	93	43	l	l	NNP
cord-023443-pvz7dll9	93	44	)	)	-RRB-
cord-023443-pvz7dll9	93	45	,	,	,
cord-023443-pvz7dll9	93	46	P	p	NN
cord-023443-pvz7dll9	93	47	¼	¼	CD
cord-023443-pvz7dll9	93	48	0.02	0.02	CD
cord-023443-pvz7dll9	93	49	]	]	-RRB-
cord-023443-pvz7dll9	93	50	.	.	.
cord-023443-pvz7dll9	94	1	The	the	DT
cord-023443-pvz7dll9	94	2	differences	difference	NNS
cord-023443-pvz7dll9	94	3	in	in	IN
cord-023443-pvz7dll9	94	4	MBL	MBL	NNP
cord-023443-pvz7dll9	94	5	levels	level	NNS
cord-023443-pvz7dll9	94	6	between	between	IN
cord-023443-pvz7dll9	94	7	patients	patient	NNS
cord-023443-pvz7dll9	94	8	with	with	IN
cord-023443-pvz7dll9	94	9	and	and	CC
cord-023443-pvz7dll9	94	10	without	without	IN
cord-023443-pvz7dll9	94	11	vascular	vascular	JJ
cord-023443-pvz7dll9	94	12	complications	complication	NNS
cord-023443-pvz7dll9	94	13	were	be	VBD
cord-023443-pvz7dll9	94	14	driven	drive	VBN
cord-023443-pvz7dll9	94	15	primarily	primarily	RB
cord-023443-pvz7dll9	94	16	by	by	IN
cord-023443-pvz7dll9	94	17	pronounced	pronounce	VBN
cord-023443-pvz7dll9	94	18	differences	difference	NNS
cord-023443-pvz7dll9	94	19	among	among	IN
cord-023443-pvz7dll9	94	20	carriers	carrier	NNS
cord-023443-pvz7dll9	94	21	of	of	IN
cord-023443-pvz7dll9	94	22	high	high	JJ
cord-023443-pvz7dll9	94	23	MBL	MBL	NNP
cord-023443-pvz7dll9	94	24	genotypes	genotype	NNS
cord-023443-pvz7dll9	94	25	(	(	-LRB-
cord-023443-pvz7dll9	94	26	P	p	NN
cord-023443-pvz7dll9	94	27	<	<	XX
cord-023443-pvz7dll9	94	28	0.0001	0.0001	CD
cord-023443-pvz7dll9	94	29	)	)	-RRB-
cord-023443-pvz7dll9	94	30	.	.	.
cord-023443-pvz7dll9	95	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	95	2	findings	finding	NNS
cord-023443-pvz7dll9	95	3	suggest	suggest	VBP
cord-023443-pvz7dll9	95	4	that	that	IN
cord-023443-pvz7dll9	95	5	MBL	MBL	NNP
cord-023443-pvz7dll9	95	6	may	may	MD
cord-023443-pvz7dll9	95	7	be	be	VB
cord-023443-pvz7dll9	95	8	involved	involve	VBN
cord-023443-pvz7dll9	95	9	in	in	IN
cord-023443-pvz7dll9	95	10	the	the	DT
cord-023443-pvz7dll9	95	11	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	95	12	of	of	IN
cord-023443-pvz7dll9	95	13	microvascular	microvascular	JJ
cord-023443-pvz7dll9	95	14	and	and	CC
cord-023443-pvz7dll9	95	15	macrovascular	macrovascular	JJ
cord-023443-pvz7dll9	95	16	complications	complication	NNS
cord-023443-pvz7dll9	95	17	in	in	IN
cord-023443-pvz7dll9	95	18	type	type	NN
cord-023443-pvz7dll9	95	19	1	1	CD
cord-023443-pvz7dll9	95	20	diabetes	diabetes	NN
cord-023443-pvz7dll9	95	21	and	and	CC
cord-023443-pvz7dll9	95	22	that	that	DT
cord-023443-pvz7dll9	95	23	determination	determination	NN
cord-023443-pvz7dll9	95	24	of	of	IN
cord-023443-pvz7dll9	95	25	MBL	MBL	NNP
cord-023443-pvz7dll9	95	26	status	status	NN
cord-023443-pvz7dll9	95	27	might	may	MD
cord-023443-pvz7dll9	95	28	be	be	VB
cord-023443-pvz7dll9	95	29	used	use	VBN
cord-023443-pvz7dll9	95	30	to	to	TO
cord-023443-pvz7dll9	95	31	identify	identify	VB
cord-023443-pvz7dll9	95	32	patients	patient	NNS
cord-023443-pvz7dll9	95	33	at	at	IN
cord-023443-pvz7dll9	95	34	increased	increase	VBN
cord-023443-pvz7dll9	95	35	risk	risk	NN
cord-023443-pvz7dll9	95	36	of	of	IN
cord-023443-pvz7dll9	95	37	developing	develop	VBG
cord-023443-pvz7dll9	95	38	these	these	DT
cord-023443-pvz7dll9	95	39	complications	complication	NNS
cord-023443-pvz7dll9	95	40	.	.	.
cord-023443-pvz7dll9	96	1	Neuroimmunology	Neuroimmunology	NNP
cord-023443-pvz7dll9	96	2	Unit	Unit	NNP
cord-023443-pvz7dll9	96	3	,	,	,
cord-023443-pvz7dll9	96	4	Center	Center	NNP
cord-023443-pvz7dll9	96	5	for	for	IN
cord-023443-pvz7dll9	96	6	Molecular	Molecular	NNP
cord-023443-pvz7dll9	96	7	Medicine	Medicine	NNP
cord-023443-pvz7dll9	96	8	,	,	,
cord-023443-pvz7dll9	96	9	Karolinska	Karolinska	NNP
cord-023443-pvz7dll9	96	10	Institutet	Institutet	NNP
cord-023443-pvz7dll9	96	11	,	,	,
cord-023443-pvz7dll9	96	12	Stockholm	Stockholm	NNP
cord-023443-pvz7dll9	96	13	,	,	,
cord-023443-pvz7dll9	96	14	Sweden	Sweden	NNP
cord-023443-pvz7dll9	96	15	.	.	.
cord-023443-pvz7dll9	97	1	E	e	NN
cord-023443-pvz7dll9	97	2	-	-	NN
cord-023443-pvz7dll9	97	3	mail	mail	NN
cord-023443-pvz7dll9	97	4	:	:	:
cord-023443-pvz7dll9	98	1	judit.wefer@cmm.ki.se	judit.wefer@cmm.ki.se	JJ
cord-023443-pvz7dll9	98	2	DNA	dna	NN
cord-023443-pvz7dll9	98	3	vaccine	vaccine	NN
cord-023443-pvz7dll9	98	4	coding	code	VBG
cord-023443-pvz7dll9	98	5	for	for	IN
cord-023443-pvz7dll9	98	6	the	the	DT
cord-023443-pvz7dll9	98	7	encephalitogenic	encephalitogenic	NNP
cord-023443-pvz7dll9	98	8	peptide	peptide	NN
cord-023443-pvz7dll9	98	9	MOG	MOG	NNP
cord-023443-pvz7dll9	98	10	91	91	CD
cord-023443-pvz7dll9	98	11	-	-	HYPH
cord-023443-pvz7dll9	98	12	108	108	CD
cord-023443-pvz7dll9	98	13	protects	protect	VBZ
cord-023443-pvz7dll9	98	14	LEW.1AV1	lew.1av1	RB
cord-023443-pvz7dll9	98	15	from	from	IN
cord-023443-pvz7dll9	98	16	subsequent	subsequent	JJ
cord-023443-pvz7dll9	98	17	development	development	NN
cord-023443-pvz7dll9	98	18	of	of	IN
cord-023443-pvz7dll9	98	19	experimental	experimental	JJ
cord-023443-pvz7dll9	98	20	autoimmune	autoimmune	JJ
cord-023443-pvz7dll9	98	21	encephalomyelitis	encephalomyelitis	NN
cord-023443-pvz7dll9	98	22	(	(	-LRB-
cord-023443-pvz7dll9	98	23	EAE	EAE	NNP
cord-023443-pvz7dll9	98	24	)	)	-RRB-
cord-023443-pvz7dll9	98	25	.	.	.
cord-023443-pvz7dll9	99	1	Protection	protection	NN
cord-023443-pvz7dll9	99	2	is	be	VBZ
cord-023443-pvz7dll9	99	3	associated	associate	VBN
cord-023443-pvz7dll9	99	4	with	with	IN
cord-023443-pvz7dll9	99	5	a	a	DT
cord-023443-pvz7dll9	99	6	type	type	NN
cord-023443-pvz7dll9	99	7	1	1	CD
cord-023443-pvz7dll9	99	8	immune	immune	JJ
cord-023443-pvz7dll9	99	9	response	response	NN
cord-023443-pvz7dll9	99	10	and	and	CC
cord-023443-pvz7dll9	99	11	is	be	VBZ
cord-023443-pvz7dll9	99	12	dependent	dependent	JJ
cord-023443-pvz7dll9	99	13	on	on	IN
cord-023443-pvz7dll9	99	14	the	the	DT
cord-023443-pvz7dll9	99	15	presence	presence	NN
cord-023443-pvz7dll9	99	16	of	of	IN
cord-023443-pvz7dll9	99	17	CpG	CpG	NNP
cord-023443-pvz7dll9	99	18	DNA	DNA	NNP
cord-023443-pvz7dll9	99	19	motifs	motif	NNS
cord-023443-pvz7dll9	99	20	.	.	.
cord-023443-pvz7dll9	100	1	The	the	DT
cord-023443-pvz7dll9	100	2	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	100	3	underlying	underlie	VBG
cord-023443-pvz7dll9	100	4	the	the	DT
cord-023443-pvz7dll9	100	5	observed	observed	JJ
cord-023443-pvz7dll9	100	6	reduction	reduction	NN
cord-023443-pvz7dll9	100	7	of	of	IN
cord-023443-pvz7dll9	100	8	EAE	EAE	NNP
cord-023443-pvz7dll9	100	9	development	development	NN
cord-023443-pvz7dll9	100	10	in	in	IN
cord-023443-pvz7dll9	100	11	protected	protect	VBN
cord-023443-pvz7dll9	100	12	rats	rat	NNS
cord-023443-pvz7dll9	100	13	have	have	VBP
cord-023443-pvz7dll9	100	14	not	not	RB
cord-023443-pvz7dll9	100	15	been	be	VBN
cord-023443-pvz7dll9	100	16	fully	fully	RB
cord-023443-pvz7dll9	100	17	clarified	clarify	VBN
cord-023443-pvz7dll9	100	18	.	.	.
cord-023443-pvz7dll9	101	1	We	-PRON-	PRP
cord-023443-pvz7dll9	101	2	investigated	investigate	VBD
cord-023443-pvz7dll9	101	3	immunological	immunological	JJ
cord-023443-pvz7dll9	101	4	characteristics	characteristic	NNS
cord-023443-pvz7dll9	101	5	of	of	IN
cord-023443-pvz7dll9	101	6	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	101	7	after	after	IN
cord-023443-pvz7dll9	101	8	DNA	dna	NN
cord-023443-pvz7dll9	101	9	vaccinaton	vaccinaton	NN
cord-023443-pvz7dll9	101	10	and	and	CC
cord-023443-pvz7dll9	101	11	subsequent	subsequent	JJ
cord-023443-pvz7dll9	101	12	EAE	EAE	NNP
cord-023443-pvz7dll9	101	13	induction	induction	NN
cord-023443-pvz7dll9	101	14	.	.	.
cord-023443-pvz7dll9	102	1	We	-PRON-	PRP
cord-023443-pvz7dll9	102	2	confirm	confirm	VBP
cord-023443-pvz7dll9	102	3	that	that	IN
cord-023443-pvz7dll9	102	4	protection	protection	NN
cord-023443-pvz7dll9	102	5	was	be	VBD
cord-023443-pvz7dll9	102	6	not	not	RB
cord-023443-pvz7dll9	102	7	associated	associate	VBN
cord-023443-pvz7dll9	102	8	with	with	IN
cord-023443-pvz7dll9	102	9	suppression	suppression	NN
cord-023443-pvz7dll9	102	10	of	of	IN
cord-023443-pvz7dll9	102	11	T1	t1	NN
cord-023443-pvz7dll9	102	12	cells	cell	NNS
cord-023443-pvz7dll9	102	13	,	,	,
cord-023443-pvz7dll9	102	14	as	as	IN
cord-023443-pvz7dll9	102	15	transcription	transcription	NN
cord-023443-pvz7dll9	102	16	of	of	IN
cord-023443-pvz7dll9	102	17	the	the	DT
cord-023443-pvz7dll9	102	18	novel	novel	JJ
cord-023443-pvz7dll9	102	19	molecule	molecule	NN
cord-023443-pvz7dll9	102	20	rat	rat	NN
cord-023443-pvz7dll9	102	21	T	t	NN
cord-023443-pvz7dll9	102	22	-	-	HYPH
cord-023443-pvz7dll9	102	23	cell	cell	NN
cord-023443-pvz7dll9	102	24	immunoglobulin	immunoglobulin	NN
cord-023443-pvz7dll9	102	25	-	-	:
cord-023443-pvz7dll9	102	26	and	and	CC
cord-023443-pvz7dll9	102	27	mucindomain	mucindomain	NN
cord-023443-pvz7dll9	102	28	-	-	HYPH
cord-023443-pvz7dll9	102	29	containing	contain	VBG
cord-023443-pvz7dll9	102	30	molecule	molecule	NN
cord-023443-pvz7dll9	102	31	(	(	-LRB-
cord-023443-pvz7dll9	102	32	TIM-3	TIM-3	NNP
cord-023443-pvz7dll9	102	33	)	)	-RRB-
cord-023443-pvz7dll9	102	34	,	,	,
cord-023443-pvz7dll9	102	35	reported	report	VBN
cord-023443-pvz7dll9	102	36	to	to	TO
cord-023443-pvz7dll9	102	37	be	be	VB
cord-023443-pvz7dll9	102	38	exclusively	exclusively	RB
cord-023443-pvz7dll9	102	39	expressed	express	VBN
cord-023443-pvz7dll9	102	40	on	on	IN
cord-023443-pvz7dll9	102	41	differentiated	differentiate	VBN
cord-023443-pvz7dll9	102	42	T1	t1	NN
cord-023443-pvz7dll9	102	43	cells	cell	NNS
cord-023443-pvz7dll9	102	44	,	,	,
cord-023443-pvz7dll9	102	45	was	be	VBD
cord-023443-pvz7dll9	102	46	not	not	RB
cord-023443-pvz7dll9	102	47	altered	alter	VBN
cord-023443-pvz7dll9	102	48	by	by	IN
cord-023443-pvz7dll9	102	49	DNA	dna	NN
cord-023443-pvz7dll9	102	50	vaccination	vaccination	NN
cord-023443-pvz7dll9	102	51	.	.	.
cord-023443-pvz7dll9	103	1	We	-PRON-	PRP
cord-023443-pvz7dll9	103	2	did	do	VBD
cord-023443-pvz7dll9	103	3	not	not	RB
cord-023443-pvz7dll9	103	4	note	note	VB
cord-023443-pvz7dll9	103	5	any	any	DT
cord-023443-pvz7dll9	103	6	clonal	clonal	JJ
cord-023443-pvz7dll9	103	7	deletion	deletion	NN
cord-023443-pvz7dll9	103	8	upon	upon	IN
cord-023443-pvz7dll9	103	9	tolerization	tolerization	NN
cord-023443-pvz7dll9	103	10	,	,	,
cord-023443-pvz7dll9	103	11	but	but	CC
cord-023443-pvz7dll9	103	12	detected	detect	VBD
cord-023443-pvz7dll9	103	13	an	an	DT
cord-023443-pvz7dll9	103	14	antigen	antigen	NN
cord-023443-pvz7dll9	103	15	-	-	HYPH
cord-023443-pvz7dll9	103	16	specific	specific	JJ
cord-023443-pvz7dll9	103	17	lymphocyte	lymphocyte	NN
cord-023443-pvz7dll9	103	18	population	population	NN
cord-023443-pvz7dll9	103	19	upregulating	upregulate	VBG
cord-023443-pvz7dll9	103	20	IFNg	IFNg	NNS
cord-023443-pvz7dll9	103	21	upon	upon	IN
cord-023443-pvz7dll9	103	22	recall	recall	NN
cord-023443-pvz7dll9	103	23	stimulation	stimulation	NN
cord-023443-pvz7dll9	103	24	3	3	CD
cord-023443-pvz7dll9	103	25	weeks	week	NNS
cord-023443-pvz7dll9	103	26	after	after	IN
cord-023443-pvz7dll9	103	27	protective	protective	JJ
cord-023443-pvz7dll9	103	28	DNA	dna	NN
cord-023443-pvz7dll9	103	29	vaccination	vaccination	NN
cord-023443-pvz7dll9	103	30	.	.	.
cord-023443-pvz7dll9	104	1	In	in	IN
cord-023443-pvz7dll9	104	2	protected	protect	VBN
cord-023443-pvz7dll9	104	3	rats	rat	NNS
cord-023443-pvz7dll9	104	4	,	,	,
cord-023443-pvz7dll9	104	5	we	-PRON-	PRP
cord-023443-pvz7dll9	104	6	observed	observe	VBD
cord-023443-pvz7dll9	104	7	(	(	-LRB-
cord-023443-pvz7dll9	104	8	1	1	LS
cord-023443-pvz7dll9	104	9	)	)	-RRB-
cord-023443-pvz7dll9	104	10	no	no	DT
cord-023443-pvz7dll9	104	11	alterations	alteration	NNS
cord-023443-pvz7dll9	104	12	in	in	IN
cord-023443-pvz7dll9	104	13	antigenspecific	antigenspecific	NN
cord-023443-pvz7dll9	104	14	Th2	th2	CD
cord-023443-pvz7dll9	104	15	or	or	CC
cord-023443-pvz7dll9	104	16	Th3	th3	JJ
cord-023443-pvz7dll9	104	17	responses	response	NNS
cord-023443-pvz7dll9	104	18	,	,	,
cord-023443-pvz7dll9	104	19	(	(	-LRB-
cord-023443-pvz7dll9	104	20	2	2	LS
cord-023443-pvz7dll9	104	21	)	)	-RRB-
cord-023443-pvz7dll9	104	22	reduced	reduce	VBN
cord-023443-pvz7dll9	104	23	MHC	MHC	NNP
cord-023443-pvz7dll9	104	24	II	II	NNP
cord-023443-pvz7dll9	104	25	expression	expression	NN
cord-023443-pvz7dll9	104	26	on	on	IN
cord-023443-pvz7dll9	104	27	splenocytes	splenocytes	NNP
cord-023443-pvz7dll9	104	28	early	early	RB
cord-023443-pvz7dll9	104	29	after	after	IN
cord-023443-pvz7dll9	104	30	EAE	EAE	NNP
cord-023443-pvz7dll9	104	31	induction	induction	NN
cord-023443-pvz7dll9	104	32	,	,	,
cord-023443-pvz7dll9	104	33	(	(	-LRB-
cord-023443-pvz7dll9	104	34	3	3	LS
cord-023443-pvz7dll9	104	35	)	)	-RRB-
cord-023443-pvz7dll9	104	36	antigen	antigen	NN
cord-023443-pvz7dll9	104	37	-	-	HYPH
cord-023443-pvz7dll9	104	38	specific	specific	JJ
cord-023443-pvz7dll9	104	39	upregulation	upregulation	NN
cord-023443-pvz7dll9	104	40	of	of	IN
cord-023443-pvz7dll9	104	41	IFNb	IFNb	NNS
cord-023443-pvz7dll9	104	42	upon	upon	IN
cord-023443-pvz7dll9	104	43	recall	recall	VBP
cord-023443-pvz7dll9	104	44	stimulation	stimulation	NN
cord-023443-pvz7dll9	104	45	and	and	CC
cord-023443-pvz7dll9	104	46	(	(	-LRB-
cord-023443-pvz7dll9	104	47	4	4	LS
cord-023443-pvz7dll9	104	48	)	)	-RRB-
cord-023443-pvz7dll9	104	49	reduced	reduce	VBN
cord-023443-pvz7dll9	104	50	IL-12Rb2	il-12rb2	NN
cord-023443-pvz7dll9	104	51	on	on	IN
cord-023443-pvz7dll9	104	52	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	104	53	.	.	.
cord-023443-pvz7dll9	105	1	We	-PRON-	PRP
cord-023443-pvz7dll9	105	2	thus	thus	RB
cord-023443-pvz7dll9	105	3	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	105	4	an	an	DT
cord-023443-pvz7dll9	105	5	association	association	NN
cord-023443-pvz7dll9	105	6	of	of	IN
cord-023443-pvz7dll9	105	7	the	the	DT
cord-023443-pvz7dll9	105	8	protective	protective	JJ
cord-023443-pvz7dll9	105	9	effect	effect	NN
cord-023443-pvz7dll9	105	10	of	of	IN
cord-023443-pvz7dll9	105	11	DNA	dna	NN
cord-023443-pvz7dll9	105	12	vaccination	vaccination	NN
cord-023443-pvz7dll9	105	13	with	with	IN
cord-023443-pvz7dll9	105	14	expression	expression	NN
cord-023443-pvz7dll9	105	15	of	of	IN
cord-023443-pvz7dll9	105	16	IFNb	IFNb	NNS
cord-023443-pvz7dll9	105	17	.	.	.
cord-023443-pvz7dll9	106	1	We	-PRON-	PRP
cord-023443-pvz7dll9	106	2	are	be	VBP
cord-023443-pvz7dll9	106	3	currently	currently	RB
cord-023443-pvz7dll9	106	4	investigating	investigate	VBG
cord-023443-pvz7dll9	106	5	the	the	DT
cord-023443-pvz7dll9	106	6	cellular	cellular	JJ
cord-023443-pvz7dll9	106	7	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	106	8	behind	behind	IN
cord-023443-pvz7dll9	106	9	this	this	DT
cord-023443-pvz7dll9	106	10	IFNb	IFNb	NNS
cord-023443-pvz7dll9	106	11	-	-	HYPH
cord-023443-pvz7dll9	106	12	mediated	mediate	VBN
cord-023443-pvz7dll9	106	13	protection	protection	NN
cord-023443-pvz7dll9	106	14	.	.	.
cord-023443-pvz7dll9	107	1	Multiple	multiple	JJ
cord-023443-pvz7dll9	107	2	sclerosis	sclerosis	NN
cord-023443-pvz7dll9	107	3	(	(	-LRB-
cord-023443-pvz7dll9	107	4	MS	MS	NNP
cord-023443-pvz7dll9	107	5	)	)	-RRB-
cord-023443-pvz7dll9	107	6	is	be	VBZ
cord-023443-pvz7dll9	107	7	an	an	DT
cord-023443-pvz7dll9	107	8	autoimmune	autoimmune	JJ
cord-023443-pvz7dll9	107	9	condition	condition	NN
cord-023443-pvz7dll9	107	10	characterized	characterize	VBN
cord-023443-pvz7dll9	107	11	by	by	IN
cord-023443-pvz7dll9	107	12	degeneration	degeneration	NN
cord-023443-pvz7dll9	107	13	of	of	IN
cord-023443-pvz7dll9	107	14	nerve	nerve	NN
cord-023443-pvz7dll9	107	15	fibre	fibre	NN
cord-023443-pvz7dll9	107	16	myelin	myelin	NN
cord-023443-pvz7dll9	107	17	sheets	sheet	NNS
cord-023443-pvz7dll9	107	18	.	.	.
cord-023443-pvz7dll9	108	1	A	a	DT
cord-023443-pvz7dll9	108	2	candidate	candidate	NN
cord-023443-pvz7dll9	108	3	autoantigen	autoantigen	NN
cord-023443-pvz7dll9	108	4	,	,	,
cord-023443-pvz7dll9	108	5	myelin	myelin	JJ
cord-023443-pvz7dll9	108	6	basic	basic	JJ
cord-023443-pvz7dll9	108	7	protein	protein	NN
cord-023443-pvz7dll9	108	8	(	(	-LRB-
cord-023443-pvz7dll9	108	9	MBP	MBP	NNP
cord-023443-pvz7dll9	108	10	)	)	-RRB-
cord-023443-pvz7dll9	108	11	,	,	,
cord-023443-pvz7dll9	108	12	has	have	VBZ
cord-023443-pvz7dll9	108	13	especially	especially	RB
cord-023443-pvz7dll9	108	14	attracted	attract	VBN
cord-023443-pvz7dll9	108	15	attention	attention	NN
cord-023443-pvz7dll9	108	16	.	.	.
cord-023443-pvz7dll9	109	1	The	the	DT
cord-023443-pvz7dll9	109	2	presence	presence	NN
cord-023443-pvz7dll9	109	3	of	of	IN
cord-023443-pvz7dll9	109	4	anti	anti	JJ
cord-023443-pvz7dll9	109	5	-	-	JJ
cord-023443-pvz7dll9	109	6	MBP	mbp	JJ
cord-023443-pvz7dll9	109	7	antibodies	antibody	NNS
cord-023443-pvz7dll9	109	8	is	be	VBZ
cord-023443-pvz7dll9	109	9	a	a	DT
cord-023443-pvz7dll9	109	10	predictor	predictor	NN
cord-023443-pvz7dll9	109	11	of	of	IN
cord-023443-pvz7dll9	109	12	definite	definite	JJ
cord-023443-pvz7dll9	109	13	MS	MS	NNP
cord-023443-pvz7dll9	109	14	,	,	,
cord-023443-pvz7dll9	109	15	but	but	CC
cord-023443-pvz7dll9	109	16	their	-PRON-	PRP$
cord-023443-pvz7dll9	109	17	role	role	NN
cord-023443-pvz7dll9	109	18	in	in	IN
cord-023443-pvz7dll9	109	19	the	the	DT
cord-023443-pvz7dll9	109	20	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	109	21	remains	remain	VBZ
cord-023443-pvz7dll9	109	22	obscure	obscure	JJ
cord-023443-pvz7dll9	109	23	.	.	.
cord-023443-pvz7dll9	110	1	T	t	NN
cord-023443-pvz7dll9	110	2	cells	cell	NNS
cord-023443-pvz7dll9	110	3	have	have	VBP
cord-023443-pvz7dll9	110	4	long	long	RB
cord-023443-pvz7dll9	110	5	been	be	VBN
cord-023443-pvz7dll9	110	6	known	know	VBN
cord-023443-pvz7dll9	110	7	to	to	TO
cord-023443-pvz7dll9	110	8	play	play	VB
cord-023443-pvz7dll9	110	9	a	a	DT
cord-023443-pvz7dll9	110	10	pivotal	pivotal	JJ
cord-023443-pvz7dll9	110	11	role	role	NN
cord-023443-pvz7dll9	110	12	in	in	IN
cord-023443-pvz7dll9	110	13	the	the	DT
cord-023443-pvz7dll9	110	14	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	110	15	of	of	IN
cord-023443-pvz7dll9	110	16	MS	MS	NNP
cord-023443-pvz7dll9	110	17	.	.	.
cord-023443-pvz7dll9	111	1	Recently	recently	RB
cord-023443-pvz7dll9	111	2	,	,	,
cord-023443-pvz7dll9	111	3	an	an	DT
cord-023443-pvz7dll9	111	4	important	important	JJ
cord-023443-pvz7dll9	111	5	role	role	NN
cord-023443-pvz7dll9	111	6	for	for	IN
cord-023443-pvz7dll9	111	7	B	b	NN
cord-023443-pvz7dll9	111	8	cells	cell	NNS
cord-023443-pvz7dll9	111	9	as	as	IN
cord-023443-pvz7dll9	111	10	autoantigen	autoantigen	NN
cord-023443-pvz7dll9	111	11	-	-	HYPH
cord-023443-pvz7dll9	111	12	presenting	present	VBG
cord-023443-pvz7dll9	111	13	cells	cell	NNS
cord-023443-pvz7dll9	111	14	has	have	VBZ
cord-023443-pvz7dll9	111	15	been	be	VBN
cord-023443-pvz7dll9	111	16	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	111	17	in	in	IN
cord-023443-pvz7dll9	111	18	other	other	JJ
cord-023443-pvz7dll9	111	19	autoimmune	autoimmune	JJ
cord-023443-pvz7dll9	111	20	diseases	disease	NNS
cord-023443-pvz7dll9	111	21	,	,	,
cord-023443-pvz7dll9	111	22	including	include	VBG
cord-023443-pvz7dll9	111	23	rheumatoid	rheumatoid	NN
cord-023443-pvz7dll9	111	24	arthritis	arthritis	NN
cord-023443-pvz7dll9	111	25	and	and	CC
cord-023443-pvz7dll9	111	26	diabetes	diabetes	NN
cord-023443-pvz7dll9	111	27	.	.	.
cord-023443-pvz7dll9	112	1	The	the	DT
cord-023443-pvz7dll9	112	2	uptake	uptake	NN
cord-023443-pvz7dll9	112	3	of	of	IN
cord-023443-pvz7dll9	112	4	MBP	MBP	NNP
cord-023443-pvz7dll9	112	5	by	by	IN
cord-023443-pvz7dll9	112	6	B	b	NN
cord-023443-pvz7dll9	112	7	cells	cell	NNS
cord-023443-pvz7dll9	112	8	and	and	CC
cord-023443-pvz7dll9	112	9	the	the	DT
cord-023443-pvz7dll9	112	10	presentation	presentation	NN
cord-023443-pvz7dll9	112	11	of	of	IN
cord-023443-pvz7dll9	112	12	MBP	MBP	NNP
cord-023443-pvz7dll9	112	13	-	-	HYPH
cord-023443-pvz7dll9	112	14	derive	derive	VBP
cord-023443-pvz7dll9	112	15	peptides	peptide	NNS
cord-023443-pvz7dll9	112	16	to	to	IN
cord-023443-pvz7dll9	112	17	T	T	NNP
cord-023443-pvz7dll9	112	18	helper	helper	NN
cord-023443-pvz7dll9	112	19	(	(	-LRB-
cord-023443-pvz7dll9	112	20	Th	Th	NNP
cord-023443-pvz7dll9	112	21	)	)	-RRB-
cord-023443-pvz7dll9	112	22	cells	cell	NNS
cord-023443-pvz7dll9	112	23	by	by	IN
cord-023443-pvz7dll9	112	24	B	b	NN
cord-023443-pvz7dll9	112	25	cells	cell	NNS
cord-023443-pvz7dll9	112	26	may	may	MD
cord-023443-pvz7dll9	112	27	be	be	VB
cord-023443-pvz7dll9	112	28	promoted	promote	VBN
cord-023443-pvz7dll9	112	29	by	by	IN
cord-023443-pvz7dll9	112	30	the	the	DT
cord-023443-pvz7dll9	112	31	formation	formation	NN
cord-023443-pvz7dll9	112	32	of	of	IN
cord-023443-pvz7dll9	112	33	complement	complement	NN
cord-023443-pvz7dll9	112	34	(	(	-LRB-
cord-023443-pvz7dll9	112	35	C	c	NN
cord-023443-pvz7dll9	112	36	)	)	-RRB-
cord-023443-pvz7dll9	112	37	activating	activate	VBG
cord-023443-pvz7dll9	112	38	immune	immune	JJ
cord-023443-pvz7dll9	112	39	complexes	complex	NNS
cord-023443-pvz7dll9	112	40	(	(	-LRB-
cord-023443-pvz7dll9	112	41	ICs	ICs	NNP
cord-023443-pvz7dll9	112	42	)	)	-RRB-
cord-023443-pvz7dll9	112	43	between	between	IN
cord-023443-pvz7dll9	112	44	MBP	MBP	NNP
cord-023443-pvz7dll9	112	45	and	and	CC
cord-023443-pvz7dll9	112	46	natural	natural	JJ
cord-023443-pvz7dll9	112	47	autoantibodies	autoantibody	NNS
cord-023443-pvz7dll9	112	48	in	in	IN
cord-023443-pvz7dll9	112	49	healthy	healthy	JJ
cord-023443-pvz7dll9	112	50	individuals	individual	NNS
cord-023443-pvz7dll9	112	51	and	and	CC
cord-023443-pvz7dll9	112	52	disease	disease	NN
cord-023443-pvz7dll9	112	53	-	-	HYPH
cord-023443-pvz7dll9	112	54	associated	associate	VBN
cord-023443-pvz7dll9	112	55	anti	anti	JJ
cord-023443-pvz7dll9	112	56	-	-	JJ
cord-023443-pvz7dll9	112	57	MBP	mbp	JJ
cord-023443-pvz7dll9	112	58	antibodies	antibody	NNS
cord-023443-pvz7dll9	112	59	in	in	IN
cord-023443-pvz7dll9	112	60	MS	MS	NNP
cord-023443-pvz7dll9	112	61	patients	patient	NNS
cord-023443-pvz7dll9	112	62	,	,	,
cord-023443-pvz7dll9	112	63	respectively	respectively	RB
cord-023443-pvz7dll9	112	64	.	.	.
cord-023443-pvz7dll9	113	1	We	-PRON-	PRP
cord-023443-pvz7dll9	113	2	have	have	VBP
cord-023443-pvz7dll9	113	3	investigated	investigate	VBN
cord-023443-pvz7dll9	113	4	the	the	DT
cord-023443-pvz7dll9	113	5	formation	formation	NN
cord-023443-pvz7dll9	113	6	of	of	IN
cord-023443-pvz7dll9	113	7	MBP	MBP	NNP
cord-023443-pvz7dll9	113	8	-	-	HYPH
cord-023443-pvz7dll9	113	9	containing	contain	VBG
cord-023443-pvz7dll9	113	10	IC	IC	NNP
cord-023443-pvz7dll9	113	11	,	,	,
cord-023443-pvz7dll9	113	12	the	the	DT
cord-023443-pvz7dll9	113	13	binding	binding	NN
cord-023443-pvz7dll9	113	14	of	of	IN
cord-023443-pvz7dll9	113	15	MBP	MBP	NNP
cord-023443-pvz7dll9	113	16	to	to	IN
cord-023443-pvz7dll9	113	17	B	b	NN
cord-023443-pvz7dll9	113	18	cells	cell	NNS
cord-023443-pvz7dll9	113	19	,	,	,
cord-023443-pvz7dll9	113	20	the	the	DT
cord-023443-pvz7dll9	113	21	MBP	MBP	NNP
cord-023443-pvz7dll9	113	22	-	-	HYPH
cord-023443-pvz7dll9	113	23	elicited	elicit	VBN
cord-023443-pvz7dll9	113	24	induction	induction	NN
cord-023443-pvz7dll9	113	25	of	of	IN
cord-023443-pvz7dll9	113	26	Th	Th	NNP
cord-023443-pvz7dll9	113	27	-	-	HYPH
cord-023443-pvz7dll9	113	28	cell	cell	NN
cord-023443-pvz7dll9	113	29	and	and	CC
cord-023443-pvz7dll9	113	30	B	b	NN
cord-023443-pvz7dll9	113	31	-	-	HYPH
cord-023443-pvz7dll9	113	32	cell	cell	NN
cord-023443-pvz7dll9	113	33	proliferation	proliferation	NN
cord-023443-pvz7dll9	113	34	and	and	CC
cord-023443-pvz7dll9	113	35	the	the	DT
cord-023443-pvz7dll9	113	36	cytokine	cytokine	NN
cord-023443-pvz7dll9	113	37	production	production	NN
cord-023443-pvz7dll9	113	38	in	in	IN
cord-023443-pvz7dll9	113	39	peripheral	peripheral	JJ
cord-023443-pvz7dll9	113	40	blood	blood	NN
cord-023443-pvz7dll9	113	41	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	113	42	cells	cell	NNS
cord-023443-pvz7dll9	113	43	(	(	-LRB-
cord-023443-pvz7dll9	113	44	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	113	45	)	)	-RRB-
cord-023443-pvz7dll9	113	46	from	from	IN
cord-023443-pvz7dll9	113	47	healthy	healthy	JJ
cord-023443-pvz7dll9	113	48	donors	donor	NNS
cord-023443-pvz7dll9	113	49	grown	grow	VBN
cord-023443-pvz7dll9	113	50	in	in	IN
cord-023443-pvz7dll9	113	51	the	the	DT
cord-023443-pvz7dll9	113	52	presence	presence	NN
cord-023443-pvz7dll9	113	53	of	of	IN
cord-023443-pvz7dll9	113	54	intact	intact	JJ
cord-023443-pvz7dll9	113	55	or	or	CC
cord-023443-pvz7dll9	113	56	C	c	NN
cord-023443-pvz7dll9	113	57	-	-	HYPH
cord-023443-pvz7dll9	113	58	inactivated	inactivate	VBN
cord-023443-pvz7dll9	113	59	serum	serum	NN
cord-023443-pvz7dll9	113	60	from	from	IN
cord-023443-pvz7dll9	113	61	healthy	healthy	JJ
cord-023443-pvz7dll9	113	62	donors	donor	NNS
cord-023443-pvz7dll9	113	63	or	or	CC
cord-023443-pvz7dll9	113	64	patients	patient	NNS
cord-023443-pvz7dll9	113	65	with	with	IN
cord-023443-pvz7dll9	113	66	MS	MS	NNP
cord-023443-pvz7dll9	113	67	.	.	.
cord-023443-pvz7dll9	114	1	While	while	IN
cord-023443-pvz7dll9	114	2	MBP	MBP	NNP
cord-023443-pvz7dll9	114	3	did	do	VBD
cord-023443-pvz7dll9	114	4	not	not	RB
cord-023443-pvz7dll9	114	5	induce	induce	VB
cord-023443-pvz7dll9	114	6	measurable	measurable	JJ
cord-023443-pvz7dll9	114	7	proliferation	proliferation	NN
cord-023443-pvz7dll9	114	8	of	of	IN
cord-023443-pvz7dll9	114	9	B	b	NN
cord-023443-pvz7dll9	114	10	cells	cell	NNS
cord-023443-pvz7dll9	114	11	nor	nor	CC
cord-023443-pvz7dll9	114	12	CD4	CD4	NNP
cord-023443-pvz7dll9	114	13	þ	þ	NNP
cord-023443-pvz7dll9	114	14	T	t	NN
cord-023443-pvz7dll9	114	15	cells	cell	NNS
cord-023443-pvz7dll9	114	16	,	,	,
cord-023443-pvz7dll9	114	17	we	-PRON-	PRP
cord-023443-pvz7dll9	114	18	observed	observe	VBD
cord-023443-pvz7dll9	114	19	the	the	DT
cord-023443-pvz7dll9	114	20	production	production	NN
cord-023443-pvz7dll9	114	21	of	of	IN
cord-023443-pvz7dll9	114	22	TNF	TNF	NNP
cord-023443-pvz7dll9	114	23	-	-	HYPH
cord-023443-pvz7dll9	114	24	a	a	NNP
cord-023443-pvz7dll9	114	25	,	,	,
cord-023443-pvz7dll9	114	26	IFN	IFN	NNP
cord-023443-pvz7dll9	114	27	-	-	HYPH
cord-023443-pvz7dll9	114	28	g	g	NNP
cord-023443-pvz7dll9	114	29	and	and	CC
cord-023443-pvz7dll9	114	30	IL-10	IL-10	NNP
cord-023443-pvz7dll9	114	31	by	by	IN
cord-023443-pvz7dll9	114	32	PBMC	PBMC	NNP
cord-023443-pvz7dll9	114	33	in	in	IN
cord-023443-pvz7dll9	114	34	response	response	NN
cord-023443-pvz7dll9	114	35	to	to	IN
cord-023443-pvz7dll9	114	36	incubation	incubation	NN
cord-023443-pvz7dll9	114	37	with	with	IN
cord-023443-pvz7dll9	114	38	MBP	MBP	NNP
cord-023443-pvz7dll9	114	39	in	in	IN
cord-023443-pvz7dll9	114	40	the	the	DT
cord-023443-pvz7dll9	114	41	presence	presence	NN
cord-023443-pvz7dll9	114	42	of	of	IN
cord-023443-pvz7dll9	114	43	sera	sera	NNP
cord-023443-pvz7dll9	114	44	from	from	IN
cord-023443-pvz7dll9	114	45	healthy	healthy	JJ
cord-023443-pvz7dll9	114	46	controls	control	NNS
cord-023443-pvz7dll9	114	47	as	as	RB
cord-023443-pvz7dll9	114	48	well	well	RB
cord-023443-pvz7dll9	114	49	as	as	IN
cord-023443-pvz7dll9	114	50	sera	sera	NNP
cord-023443-pvz7dll9	114	51	from	from	IN
cord-023443-pvz7dll9	114	52	MS	MS	NNP
cord-023443-pvz7dll9	114	53	patients	patient	NNS
cord-023443-pvz7dll9	114	54	.	.	.
cord-023443-pvz7dll9	115	1	By	by	IN
cord-023443-pvz7dll9	115	2	contrast	contrast	NN
cord-023443-pvz7dll9	115	3	,	,	,
cord-023443-pvz7dll9	115	4	no	no	DT
cord-023443-pvz7dll9	115	5	production	production	NN
cord-023443-pvz7dll9	115	6	of	of	IN
cord-023443-pvz7dll9	115	7	IL-2	IL-2	NNP
cord-023443-pvz7dll9	115	8	,	,	,
cord-023443-pvz7dll9	115	9	IL-4	IL-4	NNP
cord-023443-pvz7dll9	115	10	and	and	CC
cord-023443-pvz7dll9	115	11	IL-5	IL-5	NNP
cord-023443-pvz7dll9	115	12	was	be	VBD
cord-023443-pvz7dll9	115	13	detected	detect	VBN
cord-023443-pvz7dll9	115	14	.	.	.
cord-023443-pvz7dll9	116	1	We	-PRON-	PRP
cord-023443-pvz7dll9	116	2	are	be	VBP
cord-023443-pvz7dll9	116	3	currently	currently	RB
cord-023443-pvz7dll9	116	4	investigating	investigate	VBG
cord-023443-pvz7dll9	116	5	the	the	DT
cord-023443-pvz7dll9	116	6	capability	capability	NN
cord-023443-pvz7dll9	116	7	of	of	IN
cord-023443-pvz7dll9	116	8	MS	MS	NNP
cord-023443-pvz7dll9	116	9	sera	sera	NNP
cord-023443-pvz7dll9	116	10	to	to	TO
cord-023443-pvz7dll9	116	11	promote	promote	VB
cord-023443-pvz7dll9	116	12	the	the	DT
cord-023443-pvz7dll9	116	13	formation	formation	NN
cord-023443-pvz7dll9	116	14	of	of	IN
cord-023443-pvz7dll9	116	15	MBP	MBP	NNP
cord-023443-pvz7dll9	116	16	-	-	HYPH
cord-023443-pvz7dll9	116	17	containing	contain	VBG
cord-023443-pvz7dll9	116	18	IC	IC	NNP
cord-023443-pvz7dll9	116	19	and	and	CC
cord-023443-pvz7dll9	116	20	thereby	thereby	RB
cord-023443-pvz7dll9	116	21	enhance	enhance	VB
cord-023443-pvz7dll9	116	22	the	the	DT
cord-023443-pvz7dll9	116	23	cytokine	cytokine	NN
cord-023443-pvz7dll9	116	24	responses	response	NNS
cord-023443-pvz7dll9	116	25	,	,	,
cord-023443-pvz7dll9	116	26	by	by	IN
cord-023443-pvz7dll9	116	27	virtue	virtue	NN
cord-023443-pvz7dll9	116	28	of	of	IN
cord-023443-pvz7dll9	116	29	elevated	elevated	JJ
cord-023443-pvz7dll9	116	30	anti	anti	JJ
cord-023443-pvz7dll9	116	31	-	-	JJ
cord-023443-pvz7dll9	116	32	MBP	mbp	JJ
cord-023443-pvz7dll9	116	33	contents	content	NNS
cord-023443-pvz7dll9	116	34	.	.	.
cord-023443-pvz7dll9	117	1	The	the	DT
cord-023443-pvz7dll9	117	2	phagolysosomally	phagolysosomally	RB
cord-023443-pvz7dll9	117	3	localized	localized	JJ
cord-023443-pvz7dll9	117	4	acid	acid	NN
cord-023443-pvz7dll9	117	5	sphingomyelinase	sphingomyelinase	NN
cord-023443-pvz7dll9	117	6	(	(	-LRB-
cord-023443-pvz7dll9	117	7	ASMase	ASMase	NNP
cord-023443-pvz7dll9	117	8	)	)	-RRB-
cord-023443-pvz7dll9	118	1	activated	activate	VBN
cord-023443-pvz7dll9	118	2	by	by	IN
cord-023443-pvz7dll9	118	3	proinflammatory	proinflammatory	JJ
cord-023443-pvz7dll9	118	4	cytokines	cytokine	NNS
cord-023443-pvz7dll9	118	5	such	such	JJ
cord-023443-pvz7dll9	118	6	as	as	IN
cord-023443-pvz7dll9	118	7	TNF	TNF	NNP
cord-023443-pvz7dll9	118	8	and	and	CC
cord-023443-pvz7dll9	118	9	IFN	IFN	NNP
cord-023443-pvz7dll9	118	10	-	-	HYPH
cord-023443-pvz7dll9	118	11	g	g	NNP
cord-023443-pvz7dll9	119	1	generates	generate	VBZ
cord-023443-pvz7dll9	119	2	the	the	DT
cord-023443-pvz7dll9	119	3	signalling	signal	VBG
cord-023443-pvz7dll9	119	4	molecule	molecule	NN
cord-023443-pvz7dll9	119	5	ceramide	ceramide	NN
cord-023443-pvz7dll9	119	6	which	which	WDT
cord-023443-pvz7dll9	119	7	in	in	IN
cord-023443-pvz7dll9	119	8	turn	turn	NN
cord-023443-pvz7dll9	119	9	results	result	VBZ
cord-023443-pvz7dll9	119	10	in	in	IN
cord-023443-pvz7dll9	119	11	the	the	DT
cord-023443-pvz7dll9	119	12	activation	activation	NN
cord-023443-pvz7dll9	119	13	of	of	IN
cord-023443-pvz7dll9	119	14	proteases	protease	NNS
cord-023443-pvz7dll9	119	15	like	like	IN
cord-023443-pvz7dll9	120	1	cathepsin	cathepsin	NNP
cord-023443-pvz7dll9	120	2	D.	D.	NNP
cord-023443-pvz7dll9	120	3	These	these	DT
cord-023443-pvz7dll9	120	4	characteristics	characteristic	NNS
cord-023443-pvz7dll9	120	5	of	of	IN
cord-023443-pvz7dll9	120	6	ASMase	ASMase	NNP
cord-023443-pvz7dll9	120	7	suggest	suggest	VBP
cord-023443-pvz7dll9	120	8	a	a	DT
cord-023443-pvz7dll9	120	9	possible	possible	JJ
cord-023443-pvz7dll9	120	10	role	role	NN
cord-023443-pvz7dll9	120	11	of	of	IN
cord-023443-pvz7dll9	120	12	this	this	DT
cord-023443-pvz7dll9	120	13	molecule	molecule	NN
cord-023443-pvz7dll9	120	14	in	in	IN
cord-023443-pvz7dll9	120	15	the	the	DT
cord-023443-pvz7dll9	120	16	phagocytotic	phagocytotic	JJ
cord-023443-pvz7dll9	120	17	uptake	uptake	NN
cord-023443-pvz7dll9	120	18	and	and	CC
cord-023443-pvz7dll9	120	19	phagosomal	phagosomal	NN
cord-023443-pvz7dll9	120	20	degradation	degradation	NN
cord-023443-pvz7dll9	120	21	processes	process	NNS
cord-023443-pvz7dll9	120	22	of	of	IN
cord-023443-pvz7dll9	120	23	antigens	antigen	NNS
cord-023443-pvz7dll9	120	24	or	or	CC
cord-023443-pvz7dll9	120	25	in	in	IN
cord-023443-pvz7dll9	120	26	antigen	antigen	NN
cord-023443-pvz7dll9	120	27	presentation	presentation	NN
cord-023443-pvz7dll9	120	28	.	.	.
cord-023443-pvz7dll9	121	1	We	-PRON-	PRP
cord-023443-pvz7dll9	121	2	show	show	VBP
cord-023443-pvz7dll9	121	3	here	here	RB
cord-023443-pvz7dll9	121	4	that	that	IN
cord-023443-pvz7dll9	121	5	ASMase	asmase	NN
cord-023443-pvz7dll9	121	6	-/mice	-/mice	NN
cord-023443-pvz7dll9	121	7	fail	fail	VB
cord-023443-pvz7dll9	121	8	to	to	TO
cord-023443-pvz7dll9	121	9	eliminate	eliminate	VB
cord-023443-pvz7dll9	121	10	the	the	DT
cord-023443-pvz7dll9	121	11	noncytopathic	noncytopathic	JJ
cord-023443-pvz7dll9	121	12	lymphocytic	lymphocytic	JJ
cord-023443-pvz7dll9	121	13	choriomeningitis	choriomeningitis	NNP
cord-023443-pvz7dll9	121	14	(	(	-LRB-
cord-023443-pvz7dll9	121	15	LCM	LCM	NNP
cord-023443-pvz7dll9	121	16	)	)	-RRB-
cord-023443-pvz7dll9	121	17	virus	virus	NN
cord-023443-pvz7dll9	121	18	as	as	RB
cord-023443-pvz7dll9	121	19	rapidly	rapidly	RB
cord-023443-pvz7dll9	121	20	as	as	IN
cord-023443-pvz7dll9	121	21	littermate	littermate	NN
cord-023443-pvz7dll9	121	22	wildtype	wildtype	NN
cord-023443-pvz7dll9	121	23	mice	mouse	NNS
cord-023443-pvz7dll9	121	24	.	.	.
cord-023443-pvz7dll9	122	1	Investigation	investigation	NN
cord-023443-pvz7dll9	122	2	of	of	IN
cord-023443-pvz7dll9	122	3	the	the	DT
cord-023443-pvz7dll9	122	4	immune	immune	JJ
cord-023443-pvz7dll9	122	5	response	response	NN
cord-023443-pvz7dll9	122	6	revealed	reveal	VBD
cord-023443-pvz7dll9	122	7	a	a	DT
cord-023443-pvz7dll9	122	8	reduced	reduce	VBN
cord-023443-pvz7dll9	122	9	expansion	expansion	NN
cord-023443-pvz7dll9	122	10	of	of	IN
cord-023443-pvz7dll9	122	11	CD8	CD8	NNP
cord-023443-pvz7dll9	122	12	þ	þ	NNP
cord-023443-pvz7dll9	122	13	T	T	NNP
cord-023443-pvz7dll9	122	14	cells	cell	NNS
cord-023443-pvz7dll9	122	15	.	.	.
cord-023443-pvz7dll9	123	1	The	the	DT
cord-023443-pvz7dll9	123	2	secretion	secretion	NN
cord-023443-pvz7dll9	123	3	of	of	IN
cord-023443-pvz7dll9	123	4	IFN	IFN	NNP
cord-023443-pvz7dll9	123	5	-	-	HYPH
cord-023443-pvz7dll9	123	6	g	g	NNP
cord-023443-pvz7dll9	123	7	in	in	IN
cord-023443-pvz7dll9	123	8	response	response	NN
cord-023443-pvz7dll9	123	9	to	to	TO
cord-023443-pvz7dll9	123	10	contact	contact	VB
cord-023443-pvz7dll9	123	11	with	with	IN
cord-023443-pvz7dll9	123	12	target	target	NN
cord-023443-pvz7dll9	123	13	cells	cell	NNS
cord-023443-pvz7dll9	123	14	as	as	RB
cord-023443-pvz7dll9	123	15	well	well	RB
cord-023443-pvz7dll9	123	16	as	as	IN
cord-023443-pvz7dll9	123	17	the	the	DT
cord-023443-pvz7dll9	123	18	cytolytic	cytolytic	JJ
cord-023443-pvz7dll9	123	19	activity	activity	NN
cord-023443-pvz7dll9	123	20	of	of	IN
cord-023443-pvz7dll9	123	21	virus	virus	NN
cord-023443-pvz7dll9	123	22	-	-	HYPH
cord-023443-pvz7dll9	123	23	specific	specific	JJ
cord-023443-pvz7dll9	123	24	CD8	CD8	NNP
cord-023443-pvz7dll9	123	25	þ	þ	NNP
cord-023443-pvz7dll9	123	26	T	t	NN
cord-023443-pvz7dll9	123	27	cells	cell	NNS
cord-023443-pvz7dll9	123	28	was	be	VBD
cord-023443-pvz7dll9	123	29	severely	severely	RB
cord-023443-pvz7dll9	123	30	impaired	impaired	JJ
cord-023443-pvz7dll9	123	31	.	.	.
cord-023443-pvz7dll9	124	1	Additionally	additionally	RB
cord-023443-pvz7dll9	124	2	,	,	,
cord-023443-pvz7dll9	124	3	both	both	DT
cord-023443-pvz7dll9	124	4	phases	phase	NNS
cord-023443-pvz7dll9	124	5	of	of	IN
cord-023443-pvz7dll9	124	6	the	the	DT
cord-023443-pvz7dll9	124	7	LCM	LCM	NNP
cord-023443-pvz7dll9	124	8	virus	virus	NN
cord-023443-pvz7dll9	124	9	-	-	HYPH
cord-023443-pvz7dll9	124	10	specific	specific	JJ
cord-023443-pvz7dll9	124	11	DTH	DTH	NNP
cord-023443-pvz7dll9	124	12	response	response	NN
cord-023443-pvz7dll9	124	13	,	,	,
cord-023443-pvz7dll9	124	14	mediated	mediate	VBN
cord-023443-pvz7dll9	124	15	by	by	IN
cord-023443-pvz7dll9	124	16	CD8	CD8	NNP
cord-023443-pvz7dll9	124	17	þ	þ	NNP
cord-023443-pvz7dll9	124	18	and	and	CC
cord-023443-pvz7dll9	124	19	CD4	CD4	NNP
cord-023443-pvz7dll9	124	20	þ	þ	NNP
cord-023443-pvz7dll9	124	21	T	t	NN
cord-023443-pvz7dll9	124	22	cells	cell	NNS
cord-023443-pvz7dll9	124	23	consecutively	consecutively	RB
cord-023443-pvz7dll9	124	24	,	,	,
cord-023443-pvz7dll9	124	25	were	be	VBD
cord-023443-pvz7dll9	124	26	diminished	diminish	VBN
cord-023443-pvz7dll9	124	27	in	in	IN
cord-023443-pvz7dll9	124	28	ASMase	ASMase	NNP
cord-023443-pvz7dll9	124	29	-/mice	-/mice	NN
cord-023443-pvz7dll9	124	30	.	.	.
cord-023443-pvz7dll9	125	1	However	however	RB
cord-023443-pvz7dll9	125	2	,	,	,
cord-023443-pvz7dll9	125	3	the	the	DT
cord-023443-pvz7dll9	125	4	secondary	secondary	JJ
cord-023443-pvz7dll9	125	5	memory	memory	NN
cord-023443-pvz7dll9	125	6	response	response	NN
cord-023443-pvz7dll9	125	7	of	of	IN
cord-023443-pvz7dll9	125	8	virus	virus	NN
cord-023443-pvz7dll9	125	9	-	-	HYPH
cord-023443-pvz7dll9	125	10	specific	specific	JJ
cord-023443-pvz7dll9	125	11	CTL	CTL	NNP
cord-023443-pvz7dll9	125	12	was	be	VBD
cord-023443-pvz7dll9	125	13	not	not	RB
cord-023443-pvz7dll9	125	14	altered	alter	VBN
cord-023443-pvz7dll9	125	15	,	,	,
cord-023443-pvz7dll9	125	16	and	and	CC
cord-023443-pvz7dll9	125	17	the	the	DT
cord-023443-pvz7dll9	125	18	614	614	CD
cord-023443-pvz7dll9	125	19	Abstracts	abstract	NNS
cord-023443-pvz7dll9	125	20	.................................................................................................................................................................................................	.................................................................................................................................................................................................	.
cord-023443-pvz7dll9	126	1	virus	virus	NN
cord-023443-pvz7dll9	126	2	was	be	VBD
cord-023443-pvz7dll9	126	3	effectively	effectively	RB
cord-023443-pvz7dll9	126	4	controlled	control	VBN
cord-023443-pvz7dll9	126	5	for	for	IN
cord-023443-pvz7dll9	126	6	at	at	RB
cord-023443-pvz7dll9	126	7	least	least	JJS
cord-023443-pvz7dll9	126	8	3	3	CD
cord-023443-pvz7dll9	126	9	months	month	NNS
cord-023443-pvz7dll9	126	10	by	by	IN
cord-023443-pvz7dll9	126	11	ASMase	ASMase	NNP
cord-023443-pvz7dll9	126	12	-/mice	-/mice	NN
cord-023443-pvz7dll9	126	13	.	.	.
cord-023443-pvz7dll9	127	1	In	in	IN
cord-023443-pvz7dll9	127	2	conclusion	conclusion	NN
cord-023443-pvz7dll9	127	3	,	,	,
cord-023443-pvz7dll9	127	4	the	the	DT
cord-023443-pvz7dll9	127	5	results	result	NNS
cord-023443-pvz7dll9	127	6	of	of	IN
cord-023443-pvz7dll9	127	7	this	this	DT
cord-023443-pvz7dll9	127	8	study	study	NN
cord-023443-pvz7dll9	127	9	suggest	suggest	VBP
cord-023443-pvz7dll9	127	10	an	an	DT
cord-023443-pvz7dll9	127	11	involvement	involvement	NN
cord-023443-pvz7dll9	127	12	of	of	IN
cord-023443-pvz7dll9	127	13	the	the	DT
cord-023443-pvz7dll9	127	14	ASMase	asmase	NN
cord-023443-pvz7dll9	127	15	in	in	IN
cord-023443-pvz7dll9	127	16	the	the	DT
cord-023443-pvz7dll9	127	17	activation	activation	NN
cord-023443-pvz7dll9	127	18	,	,	,
cord-023443-pvz7dll9	127	19	expansion	expansion	NN
cord-023443-pvz7dll9	127	20	or	or	CC
cord-023443-pvz7dll9	127	21	maturation	maturation	NN
cord-023443-pvz7dll9	127	22	of	of	IN
cord-023443-pvz7dll9	127	23	virus	virus	NN
cord-023443-pvz7dll9	127	24	-	-	HYPH
cord-023443-pvz7dll9	127	25	specific	specific	JJ
cord-023443-pvz7dll9	127	26	CD8	CD8	NNP
cord-023443-pvz7dll9	127	27	þ	þ	NNP
cord-023443-pvz7dll9	127	28	T	t	NN
cord-023443-pvz7dll9	127	29	cells	cell	NNS
cord-023443-pvz7dll9	127	30	during	during	IN
cord-023443-pvz7dll9	127	31	the	the	DT
cord-023443-pvz7dll9	127	32	acute	acute	JJ
cord-023443-pvz7dll9	127	33	infection	infection	NN
cord-023443-pvz7dll9	127	34	of	of	IN
cord-023443-pvz7dll9	127	35	mice	mouse	NNS
cord-023443-pvz7dll9	127	36	with	with	IN
cord-023443-pvz7dll9	127	37	the	the	DT
cord-023443-pvz7dll9	127	38	LCM	LCM	NNP
cord-023443-pvz7dll9	127	39	virus	virus	NN
cord-023443-pvz7dll9	127	40	.	.	.
cord-023443-pvz7dll9	128	1	Novel	Novel	NNP
cord-023443-pvz7dll9	128	2	Markers	Markers	NNPS
cord-023443-pvz7dll9	128	3	for	for	IN
cord-023443-pvz7dll9	128	4	Alternative	Alternative	NNP
cord-023443-pvz7dll9	128	5	Activation	Activation	NNP
cord-023443-pvz7dll9	128	6	of	of	IN
cord-023443-pvz7dll9	128	7	Macrophages	Macrophages	NNPS
cord-023443-pvz7dll9	128	8	:	:	:
cord-023443-pvz7dll9	128	9	Macrophage	Macrophage	NNP
cord-023443-pvz7dll9	128	10	Galactose	Galactose	NNP
cord-023443-pvz7dll9	128	11	-	-	HYPH
cord-023443-pvz7dll9	128	12	Type	Type	NNP
cord-023443-pvz7dll9	128	13	C	c	NN
cord-023443-pvz7dll9	128	14	-	-	HYPH
cord-023443-pvz7dll9	128	15	Type	Type	NNP
cord-023443-pvz7dll9	128	16	Lectins	Lectins	NNP
cord-023443-pvz7dll9	128	17	1	1	CD
cord-023443-pvz7dll9	128	18	and	and	CC
cord-023443-pvz7dll9	128	19	2	2	CD
cord-023443-pvz7dll9	129	1	In	in	IN
cord-023443-pvz7dll9	129	2	parallel	parallel	NN
cord-023443-pvz7dll9	129	3	with	with	IN
cord-023443-pvz7dll9	129	4	the	the	DT
cord-023443-pvz7dll9	129	5	Th1	th1	CD
cord-023443-pvz7dll9	129	6	/	/	SYM
cord-023443-pvz7dll9	129	7	Th2	th2	CD
cord-023443-pvz7dll9	129	8	dichotomy	dichotomy	NN
cord-023443-pvz7dll9	129	9	,	,	,
cord-023443-pvz7dll9	129	10	macrophages	macrophage	NNS
cord-023443-pvz7dll9	129	11	are	be	VBP
cord-023443-pvz7dll9	129	12	capable	capable	JJ
cord-023443-pvz7dll9	129	13	of	of	IN
cord-023443-pvz7dll9	129	14	developing	develop	VBG
cord-023443-pvz7dll9	129	15	into	into	IN
cord-023443-pvz7dll9	129	16	functionally	functionally	RB
cord-023443-pvz7dll9	129	17	and	and	CC
cord-023443-pvz7dll9	129	18	molecularly	molecularly	RB
cord-023443-pvz7dll9	129	19	distinct	distinct	JJ
cord-023443-pvz7dll9	129	20	subpopulations	subpopulation	NNS
cord-023443-pvz7dll9	129	21	,	,	,
cord-023443-pvz7dll9	129	22	due	due	IN
cord-023443-pvz7dll9	129	23	to	to	IN
cord-023443-pvz7dll9	129	24	differences	difference	NNS
cord-023443-pvz7dll9	129	25	in	in	IN
cord-023443-pvz7dll9	129	26	,	,	,
cord-023443-pvz7dll9	129	27	for	for	IN
cord-023443-pvz7dll9	129	28	example	example	NN
cord-023443-pvz7dll9	129	29	cytokine	cytokine	NN
cord-023443-pvz7dll9	129	30	environment	environment	NN
cord-023443-pvz7dll9	129	31	and	and	CC
cord-023443-pvz7dll9	129	32	pathological	pathological	JJ
cord-023443-pvz7dll9	129	33	conditions	condition	NNS
cord-023443-pvz7dll9	129	34	.	.	.
cord-023443-pvz7dll9	130	1	While	while	IN
cord-023443-pvz7dll9	130	2	the	the	DT
cord-023443-pvz7dll9	130	3	best	well	RBS
cord-023443-pvz7dll9	130	4	-	-	HYPH
cord-023443-pvz7dll9	130	5	studied	study	VBN
cord-023443-pvz7dll9	130	6	,	,	,
cord-023443-pvz7dll9	130	7	classically	classically	RB
cord-023443-pvz7dll9	130	8	activated	activate	VBN
cord-023443-pvz7dll9	130	9	macrophage	macrophage	NN
cord-023443-pvz7dll9	130	10	is	be	VBZ
cord-023443-pvz7dll9	130	11	induced	induce	VBN
cord-023443-pvz7dll9	130	12	by	by	IN
cord-023443-pvz7dll9	130	13	type	type	NN
cord-023443-pvz7dll9	131	1	I	-PRON-	PRP
cord-023443-pvz7dll9	131	2	stimuli	stimulus	NNS
cord-023443-pvz7dll9	131	3	such	such	JJ
cord-023443-pvz7dll9	131	4	as	as	IN
cord-023443-pvz7dll9	131	5	IFN	IFN	NNP
cord-023443-pvz7dll9	131	6	-	-	HYPH
cord-023443-pvz7dll9	131	7	g	g	NNP
cord-023443-pvz7dll9	131	8	,	,	,
cord-023443-pvz7dll9	132	1	a	a	DT
cord-023443-pvz7dll9	132	2	type	type	NN
cord-023443-pvz7dll9	132	3	II	II	NNP
cord-023443-pvz7dll9	132	4	cytokine	cytokine	NN
cord-023443-pvz7dll9	132	5	environment	environment	NN
cord-023443-pvz7dll9	132	6	antagonizes	antagonize	VBZ
cord-023443-pvz7dll9	132	7	the	the	DT
cord-023443-pvz7dll9	132	8	classical	classical	JJ
cord-023443-pvz7dll9	132	9	activation	activation	NN
cord-023443-pvz7dll9	132	10	of	of	IN
cord-023443-pvz7dll9	132	11	macrophages	macrophage	NNS
cord-023443-pvz7dll9	132	12	and	and	CC
cord-023443-pvz7dll9	132	13	is	be	VBZ
cord-023443-pvz7dll9	132	14	capable	capable	JJ
cord-023443-pvz7dll9	132	15	of	of	IN
cord-023443-pvz7dll9	132	16	alternatively	alternatively	RB
cord-023443-pvz7dll9	132	17	activating	activate	VBG
cord-023443-pvz7dll9	132	18	macrophages	macrophage	NNS
cord-023443-pvz7dll9	132	19	.	.	.
cord-023443-pvz7dll9	133	1	However	however	RB
cord-023443-pvz7dll9	133	2	,	,	,
cord-023443-pvz7dll9	133	3	molecular	molecular	JJ
cord-023443-pvz7dll9	133	4	markers	marker	NNS
cord-023443-pvz7dll9	133	5	associated	associate	VBN
cord-023443-pvz7dll9	133	6	with	with	IN
cord-023443-pvz7dll9	133	7	these	these	DT
cord-023443-pvz7dll9	133	8	type	type	NN
cord-023443-pvz7dll9	133	9	II	ii	CD
cord-023443-pvz7dll9	133	10	cytokine	cytokine	NN
cord-023443-pvz7dll9	133	11	-	-	HYPH
cord-023443-pvz7dll9	133	12	dependent	dependent	JJ
cord-023443-pvz7dll9	133	13	,	,	,
cord-023443-pvz7dll9	133	14	alternatively	alternatively	RB
cord-023443-pvz7dll9	133	15	activated	activate	VBN
cord-023443-pvz7dll9	133	16	macrophages	macrophage	NNS
cord-023443-pvz7dll9	133	17	remain	remain	VBP
cord-023443-pvz7dll9	133	18	scarce	scarce	JJ
cord-023443-pvz7dll9	133	19	.	.	.
cord-023443-pvz7dll9	134	1	Besides	besides	IN
cord-023443-pvz7dll9	134	2	the	the	DT
cord-023443-pvz7dll9	134	3	earlier	early	RBR
cord-023443-pvz7dll9	134	4	documented	document	VBN
cord-023443-pvz7dll9	134	5	markers	marker	NNS
cord-023443-pvz7dll9	134	6	macrophage	macrophage	NN
cord-023443-pvz7dll9	134	7	mannose	mannose	NN
cord-023443-pvz7dll9	134	8	receptor	receptor	NN
cord-023443-pvz7dll9	134	9	and	and	CC
cord-023443-pvz7dll9	134	10	arginase	arginase	NNP
cord-023443-pvz7dll9	134	11	1	1	CD
cord-023443-pvz7dll9	134	12	,	,	,
cord-023443-pvz7dll9	134	13	we	-PRON-	PRP
cord-023443-pvz7dll9	134	14	recently	recently	RB
cord-023443-pvz7dll9	134	15	demonstrated	demonstrate	VBD
cord-023443-pvz7dll9	134	16	that	that	IN
cord-023443-pvz7dll9	134	17	murine	murine	NN
cord-023443-pvz7dll9	134	18	alternatively	alternatively	RB
cord-023443-pvz7dll9	134	19	activated	activate	VBN
cord-023443-pvz7dll9	134	20	macrophages	macrophage	NNS
cord-023443-pvz7dll9	134	21	are	be	VBP
cord-023443-pvz7dll9	134	22	characterized	characterize	VBN
cord-023443-pvz7dll9	134	23	by	by	IN
cord-023443-pvz7dll9	134	24	increased	increase	VBN
cord-023443-pvz7dll9	134	25	expression	expression	NN
cord-023443-pvz7dll9	134	26	of	of	IN
cord-023443-pvz7dll9	134	27	FIZZ1	FIZZ1	NNP
cord-023443-pvz7dll9	134	28	and	and	CC
cord-023443-pvz7dll9	134	29	Ym	Ym	NNP
cord-023443-pvz7dll9	134	30	.	.	.
cord-023443-pvz7dll9	135	1	We	-PRON-	PRP
cord-023443-pvz7dll9	135	2	now	now	RB
cord-023443-pvz7dll9	135	3	report	report	VBP
cord-023443-pvz7dll9	135	4	that	that	DT
cord-023443-pvz7dll9	135	5	expression	expression	NN
cord-023443-pvz7dll9	135	6	of	of	IN
cord-023443-pvz7dll9	135	7	the	the	DT
cord-023443-pvz7dll9	135	8	two	two	CD
cord-023443-pvz7dll9	135	9	members	member	NNS
cord-023443-pvz7dll9	135	10	of	of	IN
cord-023443-pvz7dll9	135	11	the	the	DT
cord-023443-pvz7dll9	135	12	mouse	mouse	NN
cord-023443-pvz7dll9	135	13	macrophage	macrophage	NN
cord-023443-pvz7dll9	135	14	galactose	galactose	NN
cord-023443-pvz7dll9	135	15	-	-	HYPH
cord-023443-pvz7dll9	135	16	type	type	NN
cord-023443-pvz7dll9	135	17	C	c	NN
cord-023443-pvz7dll9	135	18	-	-	HYPH
cord-023443-pvz7dll9	135	19	type	type	NN
cord-023443-pvz7dll9	135	20	lectin	lectin	NN
cord-023443-pvz7dll9	135	21	gene	gene	NN
cord-023443-pvz7dll9	135	22	family	family	NN
cord-023443-pvz7dll9	135	23	,	,	,
cord-023443-pvz7dll9	135	24	termed	term	VBN
cord-023443-pvz7dll9	135	25	mMGL1	mmgl1	NN
cord-023443-pvz7dll9	135	26	and	and	CC
cord-023443-pvz7dll9	135	27	mMGL2	mmgl2	NN
cord-023443-pvz7dll9	135	28	,	,	,
cord-023443-pvz7dll9	135	29	is	be	VBZ
cord-023443-pvz7dll9	135	30	induced	induce	VBN
cord-023443-pvz7dll9	135	31	in	in	IN
cord-023443-pvz7dll9	135	32	diverse	diverse	JJ
cord-023443-pvz7dll9	135	33	populations	population	NNS
cord-023443-pvz7dll9	135	34	of	of	IN
cord-023443-pvz7dll9	135	35	alternatively	alternatively	RB
cord-023443-pvz7dll9	135	36	activated	activate	VBN
cord-023443-pvz7dll9	135	37	macrophages	macrophage	NNS
cord-023443-pvz7dll9	135	38	,	,	,
cord-023443-pvz7dll9	135	39	including	include	VBG
cord-023443-pvz7dll9	135	40	peritoneal	peritoneal	JJ
cord-023443-pvz7dll9	135	41	macrophages	macrophage	NNS
cord-023443-pvz7dll9	135	42	elicited	elicit	VBN
cord-023443-pvz7dll9	135	43	during	during	IN
cord-023443-pvz7dll9	135	44	infection	infection	NN
cord-023443-pvz7dll9	135	45	with	with	IN
cord-023443-pvz7dll9	135	46	the	the	DT
cord-023443-pvz7dll9	135	47	protozoan	protozoan	NN
cord-023443-pvz7dll9	135	48	Trypanosoma	Trypanosoma	NNP
cord-023443-pvz7dll9	135	49	brucei	brucei	NNP
cord-023443-pvz7dll9	135	50	or	or	CC
cord-023443-pvz7dll9	135	51	the	the	DT
cord-023443-pvz7dll9	135	52	Helminth	Helminth	NNP
cord-023443-pvz7dll9	135	53	Taenia	Taenia	NNP
cord-023443-pvz7dll9	135	54	crassiceps	crassiceps	NN
cord-023443-pvz7dll9	135	55	,	,	,
cord-023443-pvz7dll9	135	56	and	and	CC
cord-023443-pvz7dll9	135	57	alveolar	alveolar	NN
cord-023443-pvz7dll9	135	58	macrophages	macrophage	NNS
cord-023443-pvz7dll9	135	59	elicited	elicit	VBN
cord-023443-pvz7dll9	135	60	in	in	IN
cord-023443-pvz7dll9	135	61	a	a	DT
cord-023443-pvz7dll9	135	62	mouse	mouse	NN
cord-023443-pvz7dll9	135	63	model	model	NN
cord-023443-pvz7dll9	135	64	of	of	IN
cord-023443-pvz7dll9	135	65	allergic	allergic	JJ
cord-023443-pvz7dll9	135	66	asthma	asthma	NN
cord-023443-pvz7dll9	135	67	.	.	.
cord-023443-pvz7dll9	136	1	We	-PRON-	PRP
cord-023443-pvz7dll9	136	2	also	also	RB
cord-023443-pvz7dll9	136	3	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	136	4	that	that	IN
cord-023443-pvz7dll9	136	5	,	,	,
cord-023443-pvz7dll9	136	6	in	in	IN
cord-023443-pvz7dll9	136	7	vitro	vitro	FW
cord-023443-pvz7dll9	136	8	,	,	,
cord-023443-pvz7dll9	136	9	interleukin-4	interleukin-4	NNP
cord-023443-pvz7dll9	136	10	and	and	CC
cord-023443-pvz7dll9	136	11	interleukin-13	interleukin-13	NN
cord-023443-pvz7dll9	136	12	upregulate	upregulate	VBP
cord-023443-pvz7dll9	136	13	mMGL1	mmgl1	NN
cord-023443-pvz7dll9	136	14	and	and	CC
cord-023443-pvz7dll9	136	15	mMGL2	mmgl2	NN
cord-023443-pvz7dll9	136	16	expression	expression	NN
cord-023443-pvz7dll9	136	17	and	and	CC
cord-023443-pvz7dll9	136	18	that	that	IN
cord-023443-pvz7dll9	136	19	,	,	,
cord-023443-pvz7dll9	136	20	in	in	IN
cord-023443-pvz7dll9	136	21	vivo	vivo	NN
cord-023443-pvz7dll9	136	22	,	,	,
cord-023443-pvz7dll9	136	23	induction	induction	NN
cord-023443-pvz7dll9	136	24	of	of	IN
cord-023443-pvz7dll9	136	25	mMGL1	mmgl1	NN
cord-023443-pvz7dll9	137	1	and	and	CC
cord-023443-pvz7dll9	137	2	mMGL2	mmgl2	NN
cord-023443-pvz7dll9	137	3	is	be	VBZ
cord-023443-pvz7dll9	137	4	dependent	dependent	JJ
cord-023443-pvz7dll9	137	5	on	on	IN
cord-023443-pvz7dll9	137	6	interleukin-4	interleukin-4	NNP
cord-023443-pvz7dll9	137	7	receptor	receptor	NN
cord-023443-pvz7dll9	137	8	signalling	signalling	NN
cord-023443-pvz7dll9	137	9	.	.	.
cord-023443-pvz7dll9	138	1	Moreover	moreover	RB
cord-023443-pvz7dll9	138	2	,	,	,
cord-023443-pvz7dll9	138	3	we	-PRON-	PRP
cord-023443-pvz7dll9	138	4	show	show	VBP
cord-023443-pvz7dll9	138	5	that	that	IN
cord-023443-pvz7dll9	138	6	regulation	regulation	NN
cord-023443-pvz7dll9	138	7	of	of	IN
cord-023443-pvz7dll9	138	8	MGL	MGL	NNP
cord-023443-pvz7dll9	138	9	expression	expression	NN
cord-023443-pvz7dll9	138	10	is	be	VBZ
cord-023443-pvz7dll9	138	11	similar	similar	JJ
cord-023443-pvz7dll9	138	12	in	in	IN
cord-023443-pvz7dll9	138	13	human	human	JJ
cord-023443-pvz7dll9	138	14	monocytes	monocyte	NNS
cord-023443-pvz7dll9	138	15	and	and	CC
cord-023443-pvz7dll9	138	16	monocyte	monocyte	NN
cord-023443-pvz7dll9	138	17	-	-	HYPH
cord-023443-pvz7dll9	138	18	derived	derive	VBN
cord-023443-pvz7dll9	138	19	macrophages	macrophage	NNS
cord-023443-pvz7dll9	138	20	.	.	.
cord-023443-pvz7dll9	139	1	Hence	hence	RB
cord-023443-pvz7dll9	139	2	,	,	,
cord-023443-pvz7dll9	139	3	macrophage	macrophage	NN
cord-023443-pvz7dll9	139	4	galactose	galactose	NN
cord-023443-pvz7dll9	139	5	-	-	HYPH
cord-023443-pvz7dll9	139	6	type	type	NN
cord-023443-pvz7dll9	139	7	C	c	NN
cord-023443-pvz7dll9	139	8	-	-	HYPH
cord-023443-pvz7dll9	139	9	type	type	NN
cord-023443-pvz7dll9	139	10	lectins	lectin	NNS
cord-023443-pvz7dll9	139	11	represent	represent	VBP
cord-023443-pvz7dll9	139	12	novel	novel	JJ
cord-023443-pvz7dll9	139	13	markers	marker	NNS
cord-023443-pvz7dll9	139	14	for	for	IN
cord-023443-pvz7dll9	139	15	both	both	CC
cord-023443-pvz7dll9	139	16	murine	murine	JJ
cord-023443-pvz7dll9	139	17	and	and	CC
cord-023443-pvz7dll9	139	18	human	human	JJ
cord-023443-pvz7dll9	139	19	alternatively	alternatively	RB
cord-023443-pvz7dll9	139	20	activated	activate	VBN
cord-023443-pvz7dll9	139	21	macrophages	macrophage	NNS
cord-023443-pvz7dll9	139	22	;	;	:
cord-023443-pvz7dll9	139	23	thus	thus	RB
cord-023443-pvz7dll9	139	24	,	,	,
cord-023443-pvz7dll9	139	25	paving	pave	VBG
cord-023443-pvz7dll9	139	26	the	the	DT
cord-023443-pvz7dll9	139	27	way	way	NN
cord-023443-pvz7dll9	139	28	for	for	IN
cord-023443-pvz7dll9	139	29	further	further	JJ
cord-023443-pvz7dll9	139	30	characterization	characterization	NN
cord-023443-pvz7dll9	139	31	of	of	IN
cord-023443-pvz7dll9	139	32	the	the	DT
cord-023443-pvz7dll9	139	33	phenotype	phenotype	NN
cord-023443-pvz7dll9	139	34	of	of	IN
cord-023443-pvz7dll9	139	35	macrophages	macrophage	NNS
cord-023443-pvz7dll9	139	36	occurring	occur	VBG
cord-023443-pvz7dll9	139	37	in	in	IN
cord-023443-pvz7dll9	139	38	Th2	th2	CD
cord-023443-pvz7dll9	139	39	conditions	condition	NNS
cord-023443-pvz7dll9	139	40	.	.	.
cord-023443-pvz7dll9	140	1	Background	background	NN
cord-023443-pvz7dll9	140	2	:	:	:
cord-023443-pvz7dll9	141	1	Human	human	JJ
cord-023443-pvz7dll9	141	2	parvovirus	parvovirus	NN
cord-023443-pvz7dll9	141	3	B19	B19	NNP
cord-023443-pvz7dll9	141	4	(	(	-LRB-
cord-023443-pvz7dll9	141	5	B19	B19	NNP
cord-023443-pvz7dll9	141	6	)	)	-RRB-
cord-023443-pvz7dll9	141	7	is	be	VBZ
cord-023443-pvz7dll9	141	8	a	a	DT
cord-023443-pvz7dll9	141	9	ubiquitous	ubiquitous	JJ
cord-023443-pvz7dll9	141	10	pathogen	pathogen	NN
cord-023443-pvz7dll9	141	11	,	,	,
cord-023443-pvz7dll9	141	12	normally	normally	RB
cord-023443-pvz7dll9	141	13	causing	cause	VBG
cord-023443-pvz7dll9	141	14	a	a	DT
cord-023443-pvz7dll9	141	15	mild	mild	JJ
cord-023443-pvz7dll9	141	16	self	self	NN
cord-023443-pvz7dll9	141	17	-	-	HYPH
cord-023443-pvz7dll9	141	18	limiting	limit	VBG
cord-023443-pvz7dll9	141	19	disease	disease	NN
cord-023443-pvz7dll9	141	20	,	,	,
cord-023443-pvz7dll9	141	21	but	but	CC
cord-023443-pvz7dll9	141	22	also	also	RB
cord-023443-pvz7dll9	141	23	capable	capable	JJ
cord-023443-pvz7dll9	141	24	of	of	IN
cord-023443-pvz7dll9	141	25	causing	cause	VBG
cord-023443-pvz7dll9	141	26	both	both	DT
cord-023443-pvz7dll9	141	27	significant	significant	JJ
cord-023443-pvz7dll9	141	28	pathology	pathology	NN
cord-023443-pvz7dll9	141	29	and	and	CC
cord-023443-pvz7dll9	141	30	long	long	JJ
cord-023443-pvz7dll9	141	31	-	-	HYPH
cord-023443-pvz7dll9	141	32	term	term	NN
cord-023443-pvz7dll9	141	33	persistence	persistence	NN
cord-023443-pvz7dll9	141	34	.	.	.
cord-023443-pvz7dll9	142	1	The	the	DT
cord-023443-pvz7dll9	142	2	small	small	JJ
cord-023443-pvz7dll9	142	3	size	size	NN
cord-023443-pvz7dll9	142	4	and	and	CC
cord-023443-pvz7dll9	142	5	stability	stability	NN
cord-023443-pvz7dll9	142	6	of	of	IN
cord-023443-pvz7dll9	142	7	the	the	DT
cord-023443-pvz7dll9	142	8	virus	virus	NN
cord-023443-pvz7dll9	142	9	makes	make	VBZ
cord-023443-pvz7dll9	142	10	it	-PRON-	PRP
cord-023443-pvz7dll9	142	11	suitable	suitable	JJ
cord-023443-pvz7dll9	142	12	for	for	IN
cord-023443-pvz7dll9	142	13	mapping	mapping	NN
cord-023443-pvz7dll9	142	14	of	of	IN
cord-023443-pvz7dll9	142	15	the	the	DT
cord-023443-pvz7dll9	142	16	full	full	JJ
cord-023443-pvz7dll9	142	17	breath	breath	NN
cord-023443-pvz7dll9	142	18	and	and	CC
cord-023443-pvz7dll9	142	19	the	the	DT
cord-023443-pvz7dll9	142	20	kinetics	kinetic	NNS
cord-023443-pvz7dll9	142	21	of	of	IN
cord-023443-pvz7dll9	142	22	the	the	DT
cord-023443-pvz7dll9	142	23	cellular	cellular	JJ
cord-023443-pvz7dll9	142	24	immune	immune	JJ
cord-023443-pvz7dll9	142	25	responses	response	NNS
cord-023443-pvz7dll9	142	26	following	follow	VBG
cord-023443-pvz7dll9	142	27	acute	acute	JJ
cord-023443-pvz7dll9	142	28	viral	viral	JJ
cord-023443-pvz7dll9	142	29	infection	infection	NN
cord-023443-pvz7dll9	142	30	.	.	.
cord-023443-pvz7dll9	143	1	Methods	method	NNS
cord-023443-pvz7dll9	143	2	:	:	:
cord-023443-pvz7dll9	143	3	Five	five	CD
cord-023443-pvz7dll9	143	4	patients	patient	NNS
cord-023443-pvz7dll9	143	5	with	with	IN
cord-023443-pvz7dll9	143	6	acute	acute	JJ
cord-023443-pvz7dll9	143	7	primary	primary	JJ
cord-023443-pvz7dll9	143	8	B19	B19	NNP
cord-023443-pvz7dll9	143	9	infection	infection	NN
cord-023443-pvz7dll9	143	10	were	be	VBD
cord-023443-pvz7dll9	143	11	included	include	VBN
cord-023443-pvz7dll9	143	12	in	in	IN
cord-023443-pvz7dll9	143	13	the	the	DT
cord-023443-pvz7dll9	143	14	study	study	NN
cord-023443-pvz7dll9	143	15	and	and	CC
cord-023443-pvz7dll9	143	16	followed	follow	VBD
cord-023443-pvz7dll9	143	17	consecutively	consecutively	RB
cord-023443-pvz7dll9	143	18	for	for	IN
cord-023443-pvz7dll9	143	19	up	up	IN
cord-023443-pvz7dll9	143	20	to	to	TO
cord-023443-pvz7dll9	143	21	200	200	CD
cord-023443-pvz7dll9	143	22	weeks	week	NNS
cord-023443-pvz7dll9	143	23	.	.	.
cord-023443-pvz7dll9	144	1	Cellular	cellular	JJ
cord-023443-pvz7dll9	144	2	immune	immune	JJ
cord-023443-pvz7dll9	144	3	responses	response	NNS
cord-023443-pvz7dll9	144	4	were	be	VBD
cord-023443-pvz7dll9	144	5	mapped	map	VBN
cord-023443-pvz7dll9	144	6	by	by	IN
cord-023443-pvz7dll9	144	7	IFNg	IFNg	NNP
cord-023443-pvz7dll9	144	8	enzyme	enzyme	NN
cord-023443-pvz7dll9	144	9	-	-	HYPH
cord-023443-pvz7dll9	144	10	linked	link	VBN
cord-023443-pvz7dll9	144	11	immunospot	immunospot	NN
cord-023443-pvz7dll9	144	12	to	to	IN
cord-023443-pvz7dll9	144	13	overlapping	overlap	VBG
cord-023443-pvz7dll9	144	14	peptides	peptide	NNS
cord-023443-pvz7dll9	144	15	spanning	span	VBG
cord-023443-pvz7dll9	144	16	the	the	DT
cord-023443-pvz7dll9	144	17	whole	whole	JJ
cord-023443-pvz7dll9	144	18	B19	B19	NNP
cord-023443-pvz7dll9	144	19	genome	genome	NN
cord-023443-pvz7dll9	144	20	.	.	.
cord-023443-pvz7dll9	145	1	Results	result	NNS
cord-023443-pvz7dll9	145	2	:	:	:
cord-023443-pvz7dll9	146	1	In	in	IN
cord-023443-pvz7dll9	146	2	all	all	DT
cord-023443-pvz7dll9	146	3	five	five	CD
cord-023443-pvz7dll9	146	4	acutely	acutely	RB
cord-023443-pvz7dll9	146	5	infected	infected	JJ
cord-023443-pvz7dll9	146	6	patients	patient	NNS
cord-023443-pvz7dll9	146	7	,	,	,
cord-023443-pvz7dll9	146	8	we	-PRON-	PRP
cord-023443-pvz7dll9	146	9	were	be	VBD
cord-023443-pvz7dll9	146	10	able	able	JJ
cord-023443-pvz7dll9	146	11	to	to	TO
cord-023443-pvz7dll9	146	12	monitor	monitor	VB
cord-023443-pvz7dll9	146	13	the	the	DT
cord-023443-pvz7dll9	146	14	kinetics	kinetic	NNS
cord-023443-pvz7dll9	146	15	of	of	IN
cord-023443-pvz7dll9	146	16	a	a	DT
cord-023443-pvz7dll9	146	17	strong	strong	JJ
cord-023443-pvz7dll9	146	18	specific	specific	JJ
cord-023443-pvz7dll9	146	19	cellular	cellular	JJ
cord-023443-pvz7dll9	146	20	immune	immune	JJ
cord-023443-pvz7dll9	146	21	reaction	reaction	NN
cord-023443-pvz7dll9	146	22	.	.	.
cord-023443-pvz7dll9	147	1	Responses	response	NNS
cord-023443-pvz7dll9	147	2	peaked	peak	VBD
cord-023443-pvz7dll9	147	3	at	at	IN
cord-023443-pvz7dll9	147	4	levels	level	NNS
cord-023443-pvz7dll9	147	5	of	of	IN
cord-023443-pvz7dll9	147	6	850	850	CD
cord-023443-pvz7dll9	147	7	-	-	HYPH
cord-023443-pvz7dll9	147	8	1850	1850	CD
cord-023443-pvz7dll9	147	9	SFC/	SFC/	NNP
cord-023443-pvz7dll9	147	10	million	million	CD
cord-023443-pvz7dll9	147	11	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	147	12	,	,	,
cord-023443-pvz7dll9	147	13	roughly	roughly	RB
cord-023443-pvz7dll9	147	14	corresponding	correspond	VBG
cord-023443-pvz7dll9	147	15	to	to	IN
cord-023443-pvz7dll9	147	16	0.3	0.3	CD
cord-023443-pvz7dll9	147	17	-	-	SYM
cord-023443-pvz7dll9	147	18	0.6	0.6	CD
cord-023443-pvz7dll9	147	19	%	%	NN
cord-023443-pvz7dll9	147	20	B19specific	B19specific	NNP
cord-023443-pvz7dll9	147	21	CD8	CD8	NNP
cord-023443-pvz7dll9	147	22	þ	þ	NNP
cord-023443-pvz7dll9	147	23	cells	cell	NNS
cord-023443-pvz7dll9	147	24	circulating	circulate	VBG
cord-023443-pvz7dll9	147	25	in	in	IN
cord-023443-pvz7dll9	147	26	peripheral	peripheral	JJ
cord-023443-pvz7dll9	147	27	blood	blood	NN
cord-023443-pvz7dll9	147	28	at	at	IN
cord-023443-pvz7dll9	147	29	10	10	CD
cord-023443-pvz7dll9	147	30	-	-	SYM
cord-023443-pvz7dll9	147	31	80	80	CD
cord-023443-pvz7dll9	147	32	weeks	week	NNS
cord-023443-pvz7dll9	147	33	post	post	NN
cord-023443-pvz7dll9	147	34	-	-	NN
cord-023443-pvz7dll9	147	35	infection	infection	NN
cord-023443-pvz7dll9	147	36	.	.	.
cord-023443-pvz7dll9	148	1	The	the	DT
cord-023443-pvz7dll9	148	2	responses	response	NNS
cord-023443-pvz7dll9	148	3	in	in	IN
cord-023443-pvz7dll9	148	4	individual	individual	JJ
cord-023443-pvz7dll9	148	5	patients	patient	NNS
cord-023443-pvz7dll9	148	6	were	be	VBD
cord-023443-pvz7dll9	148	7	directed	direct	VBN
cord-023443-pvz7dll9	148	8	to	to	IN
cord-023443-pvz7dll9	148	9	three	three	CD
cord-023443-pvz7dll9	148	10	or	or	CC
cord-023443-pvz7dll9	148	11	four	four	CD
cord-023443-pvz7dll9	148	12	different	different	JJ
cord-023443-pvz7dll9	148	13	peptide	peptide	NN
cord-023443-pvz7dll9	148	14	pools	pool	NNS
cord-023443-pvz7dll9	148	15	,	,	,
cord-023443-pvz7dll9	148	16	and	and	CC
cord-023443-pvz7dll9	148	17	the	the	DT
cord-023443-pvz7dll9	148	18	specificity	specificity	NN
cord-023443-pvz7dll9	148	19	was	be	VBD
cord-023443-pvz7dll9	148	20	confined	confine	VBN
cord-023443-pvz7dll9	148	21	to	to	IN
cord-023443-pvz7dll9	148	22	the	the	DT
cord-023443-pvz7dll9	148	23	same	same	JJ
cord-023443-pvz7dll9	148	24	CD8	CD8	NNP
cord-023443-pvz7dll9	148	25	epitopes	epitope	NNS
cord-023443-pvz7dll9	148	26	present	present	JJ
cord-023443-pvz7dll9	148	27	in	in	IN
cord-023443-pvz7dll9	148	28	the	the	DT
cord-023443-pvz7dll9	148	29	pools	pool	NNS
cord-023443-pvz7dll9	148	30	throughout	throughout	IN
cord-023443-pvz7dll9	148	31	the	the	DT
cord-023443-pvz7dll9	148	32	follow	follow	NN
cord-023443-pvz7dll9	148	33	-	-	HYPH
cord-023443-pvz7dll9	148	34	up	up	NN
cord-023443-pvz7dll9	148	35	period	period	NN
cord-023443-pvz7dll9	148	36	.	.	.
cord-023443-pvz7dll9	149	1	The	the	DT
cord-023443-pvz7dll9	149	2	majority	majority	NN
cord-023443-pvz7dll9	149	3	of	of	IN
cord-023443-pvz7dll9	149	4	responses	response	NNS
cord-023443-pvz7dll9	149	5	were	be	VBD
cord-023443-pvz7dll9	149	6	directed	direct	VBN
cord-023443-pvz7dll9	149	7	to	to	IN
cord-023443-pvz7dll9	149	8	the	the	DT
cord-023443-pvz7dll9	149	9	virus	virus	NN
cord-023443-pvz7dll9	149	10	nonstructural	nonstructural	JJ
cord-023443-pvz7dll9	149	11	protein	protein	NN
cord-023443-pvz7dll9	149	12	,	,	,
cord-023443-pvz7dll9	149	13	only	only	RB
cord-023443-pvz7dll9	149	14	two	two	CD
cord-023443-pvz7dll9	149	15	patients	patient	NNS
cord-023443-pvz7dll9	149	16	showed	show	VBD
cord-023443-pvz7dll9	149	17	any	any	DT
cord-023443-pvz7dll9	149	18	response	response	NN
cord-023443-pvz7dll9	149	19	to	to	IN
cord-023443-pvz7dll9	149	20	the	the	DT
cord-023443-pvz7dll9	149	21	capsid	capsid	NN
cord-023443-pvz7dll9	149	22	proteins	protein	NNS
cord-023443-pvz7dll9	149	23	,	,	,
cord-023443-pvz7dll9	149	24	elicited	elicit	VBN
cord-023443-pvz7dll9	149	25	by	by	IN
cord-023443-pvz7dll9	149	26	the	the	DT
cord-023443-pvz7dll9	149	27	same	same	JJ
cord-023443-pvz7dll9	149	28	epitope	epitope	NN
cord-023443-pvz7dll9	149	29	in	in	IN
cord-023443-pvz7dll9	149	30	both	both	DT
cord-023443-pvz7dll9	149	31	cases	case	NNS
cord-023443-pvz7dll9	149	32	.	.	.
cord-023443-pvz7dll9	150	1	Conclusion	conclusion	NN
cord-023443-pvz7dll9	150	2	:	:	:
cord-023443-pvz7dll9	151	1	The	the	DT
cord-023443-pvz7dll9	151	2	cellular	cellular	JJ
cord-023443-pvz7dll9	151	3	immune	immune	JJ
cord-023443-pvz7dll9	151	4	responses	response	NNS
cord-023443-pvz7dll9	151	5	to	to	TO
cord-023443-pvz7dll9	151	6	acute	acute	JJ
cord-023443-pvz7dll9	151	7	B19	B19	NNP
cord-023443-pvz7dll9	151	8	infection	infection	NN
cord-023443-pvz7dll9	151	9	are	be	VBP
cord-023443-pvz7dll9	151	10	surprisingly	surprisingly	RB
cord-023443-pvz7dll9	151	11	narrow	narrow	JJ
cord-023443-pvz7dll9	151	12	in	in	IN
cord-023443-pvz7dll9	151	13	distribution	distribution	NN
cord-023443-pvz7dll9	151	14	and	and	CC
cord-023443-pvz7dll9	151	15	remain	remain	VB
cord-023443-pvz7dll9	151	16	at	at	IN
cord-023443-pvz7dll9	151	17	high	high	JJ
cord-023443-pvz7dll9	151	18	levels	level	NNS
cord-023443-pvz7dll9	151	19	for	for	IN
cord-023443-pvz7dll9	151	20	up	up	IN
cord-023443-pvz7dll9	151	21	to	to	TO
cord-023443-pvz7dll9	151	22	80	80	CD
cord-023443-pvz7dll9	151	23	weeks	week	NNS
cord-023443-pvz7dll9	151	24	post	post	NN
cord-023443-pvz7dll9	151	25	-	-	NN
cord-023443-pvz7dll9	151	26	infection	infection	NN
cord-023443-pvz7dll9	151	27	.	.	.
cord-023443-pvz7dll9	152	1	The	the	DT
cord-023443-pvz7dll9	152	2	initial	initial	JJ
cord-023443-pvz7dll9	152	3	epitope	epitope	NN
cord-023443-pvz7dll9	152	4	specificity	specificity	NN
cord-023443-pvz7dll9	152	5	is	be	VBZ
cord-023443-pvz7dll9	152	6	maintained	maintain	VBN
cord-023443-pvz7dll9	152	7	,	,	,
cord-023443-pvz7dll9	152	8	and	and	CC
cord-023443-pvz7dll9	152	9	the	the	DT
cord-023443-pvz7dll9	152	10	majority	majority	NN
cord-023443-pvz7dll9	152	11	of	of	IN
cord-023443-pvz7dll9	152	12	responses	response	NNS
cord-023443-pvz7dll9	152	13	target	target	VBP
cord-023443-pvz7dll9	152	14	the	the	DT
cord-023443-pvz7dll9	152	15	virus	virus	NN
cord-023443-pvz7dll9	152	16	nonstructural	nonstructural	JJ
cord-023443-pvz7dll9	152	17	protein	protein	NN
cord-023443-pvz7dll9	152	18	,	,	,
cord-023443-pvz7dll9	152	19	which	which	WDT
cord-023443-pvz7dll9	152	20	is	be	VBZ
cord-023443-pvz7dll9	152	21	not	not	RB
cord-023443-pvz7dll9	152	22	included	include	VBN
cord-023443-pvz7dll9	152	23	in	in	IN
cord-023443-pvz7dll9	152	24	vaccine	vaccine	NN
cord-023443-pvz7dll9	152	25	preparations	preparation	NNS
cord-023443-pvz7dll9	152	26	,	,	,
cord-023443-pvz7dll9	152	27	evaluated	evaluate	VBN
cord-023443-pvz7dll9	152	28	against	against	IN
cord-023443-pvz7dll9	152	29	the	the	DT
cord-023443-pvz7dll9	152	30	infection	infection	NN
cord-023443-pvz7dll9	152	31	.	.	.
cord-023443-pvz7dll9	153	1	The	the	DT
cord-023443-pvz7dll9	153	2	relationship	relationship	NN
cord-023443-pvz7dll9	153	3	between	between	IN
cord-023443-pvz7dll9	153	4	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	153	5	and	and	CC
cord-023443-pvz7dll9	153	6	malaria	malaria	NN
cord-023443-pvz7dll9	153	7	is	be	VBZ
cord-023443-pvz7dll9	153	8	controversial	controversial	JJ
cord-023443-pvz7dll9	153	9	.	.	.
cord-023443-pvz7dll9	154	1	On	on	IN
cord-023443-pvz7dll9	154	2	one	one	CD
cord-023443-pvz7dll9	154	3	hand	hand	NN
cord-023443-pvz7dll9	154	4	,	,	,
cord-023443-pvz7dll9	154	5	malaria	malaria	NN
cord-023443-pvz7dll9	154	6	may	may	MD
cord-023443-pvz7dll9	154	7	cause	cause	VB
cord-023443-pvz7dll9	154	8	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	154	9	,	,	,
cord-023443-pvz7dll9	154	10	while	while	IN
cord-023443-pvz7dll9	154	11	on	on	IN
cord-023443-pvz7dll9	154	12	the	the	DT
cord-023443-pvz7dll9	154	13	other	other	JJ
cord-023443-pvz7dll9	154	14	,	,	,
cord-023443-pvz7dll9	154	15	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	154	16	itself	-PRON-	PRP
cord-023443-pvz7dll9	154	17	may	may	MD
cord-023443-pvz7dll9	154	18	modulate	modulate	VB
cord-023443-pvz7dll9	154	19	susceptibility	susceptibility	NN
cord-023443-pvz7dll9	154	20	to	to	IN
cord-023443-pvz7dll9	154	21	the	the	DT
cord-023443-pvz7dll9	154	22	disease	disease	NN
cord-023443-pvz7dll9	154	23	.	.	.
cord-023443-pvz7dll9	155	1	We	-PRON-	PRP
cord-023443-pvz7dll9	155	2	investigated	investigate	VBD
cord-023443-pvz7dll9	155	3	the	the	DT
cord-023443-pvz7dll9	155	4	association	association	NN
cord-023443-pvz7dll9	155	5	between	between	IN
cord-023443-pvz7dll9	155	6	Plasmodium	Plasmodium	NNP
cord-023443-pvz7dll9	155	7	falciparum	falciparum	NN
cord-023443-pvz7dll9	155	8	malaria	malaria	NN
cord-023443-pvz7dll9	155	9	and	and	CC
cord-023443-pvz7dll9	155	10	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	155	11	in	in	IN
cord-023443-pvz7dll9	155	12	a	a	DT
cord-023443-pvz7dll9	155	13	cohort	cohort	NN
cord-023443-pvz7dll9	155	14	of	of	IN
cord-023443-pvz7dll9	155	15	children	child	NNS
cord-023443-pvz7dll9	155	16	living	live	VBG
cord-023443-pvz7dll9	155	17	on	on	IN
cord-023443-pvz7dll9	155	18	the	the	DT
cord-023443-pvz7dll9	155	19	coast	coast	NN
cord-023443-pvz7dll9	155	20	of	of	IN
cord-023443-pvz7dll9	155	21	Kenya	Kenya	NNP
cord-023443-pvz7dll9	155	22	.	.	.
cord-023443-pvz7dll9	156	1	The	the	DT
cord-023443-pvz7dll9	156	2	study	study	NN
cord-023443-pvz7dll9	156	3	involved	involve	VBD
cord-023443-pvz7dll9	156	4	longitudinal	longitudinal	JJ
cord-023443-pvz7dll9	156	5	follow	follow	NN
cord-023443-pvz7dll9	156	6	-	-	HYPH
cord-023443-pvz7dll9	156	7	up	up	NN
cord-023443-pvz7dll9	156	8	for	for	IN
cord-023443-pvz7dll9	156	9	clinical	clinical	JJ
cord-023443-pvz7dll9	156	10	malaria	malaria	NN
cord-023443-pvz7dll9	156	11	episodes	episode	NNS
cord-023443-pvz7dll9	156	12	and	and	CC
cord-023443-pvz7dll9	156	13	anthropometric	anthropometric	JJ
cord-023443-pvz7dll9	156	14	measurements	measurement	NNS
cord-023443-pvz7dll9	156	15	at	at	IN
cord-023443-pvz7dll9	156	16	four	four	CD
cord-023443-pvz7dll9	156	17	cross	cross	JJ
cord-023443-pvz7dll9	156	18	-	-	JJ
cord-023443-pvz7dll9	156	19	sectional	sectional	JJ
cord-023443-pvz7dll9	156	20	surveys	survey	NNS
cord-023443-pvz7dll9	156	21	.	.	.
cord-023443-pvz7dll9	157	1	We	-PRON-	PRP
cord-023443-pvz7dll9	157	2	used	use	VBD
cord-023443-pvz7dll9	157	3	Poisson	Poisson	NNP
cord-023443-pvz7dll9	157	4	regression	regression	NN
cord-023443-pvz7dll9	157	5	analysis	analysis	NN
cord-023443-pvz7dll9	157	6	to	to	TO
cord-023443-pvz7dll9	157	7	investigate	investigate	VB
cord-023443-pvz7dll9	157	8	the	the	DT
cord-023443-pvz7dll9	157	9	association	association	NN
cord-023443-pvz7dll9	157	10	between	between	IN
cord-023443-pvz7dll9	157	11	malaria	malaria	NNP
cord-023443-pvz7dll9	157	12	and	and	CC
cord-023443-pvz7dll9	157	13	nutritional	nutritional	JJ
cord-023443-pvz7dll9	157	14	status	status	NN
cord-023443-pvz7dll9	157	15	.	.	.
cord-023443-pvz7dll9	158	1	Compared	compare	VBN
cord-023443-pvz7dll9	158	2	to	to	IN
cord-023443-pvz7dll9	158	3	baseline	baseline	JJ
cord-023443-pvz7dll9	158	4	(	(	-LRB-
cord-023443-pvz7dll9	158	5	children	child	NNS
cord-023443-pvz7dll9	158	6	with	with	IN
cord-023443-pvz7dll9	158	7	a	a	DT
cord-023443-pvz7dll9	158	8	WAZ	WAZ	NNP
cord-023443-pvz7dll9	158	9	or	or	CC
cord-023443-pvz7dll9	158	10	HAZ	haz	NN
cord-023443-pvz7dll9	158	11	score	score	NN
cord-023443-pvz7dll9	158	12	of	of	IN
cord-023443-pvz7dll9	158	13	!	!	.
cord-023443-pvz7dll9	159	1	À2	À2	NNP
cord-023443-pvz7dll9	159	2	)	)	-RRB-
cord-023443-pvz7dll9	159	3	,	,	,
cord-023443-pvz7dll9	159	4	the	the	DT
cord-023443-pvz7dll9	159	5	crude	crude	JJ
cord-023443-pvz7dll9	159	6	incidence	incidence	NN
cord-023443-pvz7dll9	159	7	rate	rate	NN
cord-023443-pvz7dll9	159	8	ratios	ratio	NNS
cord-023443-pvz7dll9	159	9	(	(	-LRB-
cord-023443-pvz7dll9	159	10	IRRs	IRRs	NNP
cord-023443-pvz7dll9	159	11	)	)	-RRB-
cord-023443-pvz7dll9	159	12	for	for	IN
cord-023443-pvz7dll9	159	13	malaria	malaria	NN
cord-023443-pvz7dll9	159	14	in	in	IN
cord-023443-pvz7dll9	159	15	children	child	NNS
cord-023443-pvz7dll9	159	16	with	with	IN
cord-023443-pvz7dll9	159	17	low	low	JJ
cord-023443-pvz7dll9	159	18	HAZ	haz	NN
cord-023443-pvz7dll9	159	19	or	or	CC
cord-023443-pvz7dll9	159	20	WAZ	WAZ	NNP
cord-023443-pvz7dll9	159	21	scores	score	NNS
cord-023443-pvz7dll9	159	22	(	(	-LRB-
cord-023443-pvz7dll9	159	23	<	<	XX
cord-023443-pvz7dll9	159	24	À2	À2	NNP
cord-023443-pvz7dll9	159	25	)	)	-RRB-
cord-023443-pvz7dll9	159	26	during	during	IN
cord-023443-pvz7dll9	159	27	the	the	DT
cord-023443-pvz7dll9	159	28	period	period	NN
cord-023443-pvz7dll9	159	29	prior	prior	RB
cord-023443-pvz7dll9	159	30	to	to	IN
cord-023443-pvz7dll9	159	31	assessment	assessment	NN
cord-023443-pvz7dll9	159	32	were	be	VBD
cord-023443-pvz7dll9	159	33	1.17	1.17	CD
cord-023443-pvz7dll9	160	1	(	(	-LRB-
cord-023443-pvz7dll9	160	2	95	95	CD
cord-023443-pvz7dll9	160	3	%	%	NN
cord-023443-pvz7dll9	160	4	CI	CI	NNP
cord-023443-pvz7dll9	160	5	0.91	0.91	CD
cord-023443-pvz7dll9	160	6	-	-	HYPH
cord-023443-pvz7dll9	160	7	1.50	1.50	CD
cord-023443-pvz7dll9	160	8	;	;	:
cord-023443-pvz7dll9	160	9	0	0	CD
cord-023443-pvz7dll9	160	10	¼	¼	CD
cord-023443-pvz7dll9	160	11	0.21	0.21	CD
cord-023443-pvz7dll9	160	12	)	)	-RRB-
cord-023443-pvz7dll9	160	13	and	and	CC
cord-023443-pvz7dll9	160	14	0.94	0.94	CD
cord-023443-pvz7dll9	160	15	(	(	-LRB-
cord-023443-pvz7dll9	160	16	0.71	0.71	CD
cord-023443-pvz7dll9	160	17	-	-	SYM
cord-023443-pvz7dll9	160	18	1.25	1.25	CD
cord-023443-pvz7dll9	160	19	;	;	:
cord-023443-pvz7dll9	160	20	0.67	0.67	CD
cord-023443-pvz7dll9	160	21	)	)	-RRB-
cord-023443-pvz7dll9	160	22	,	,	,
cord-023443-pvz7dll9	160	23	respectively	respectively	RB
cord-023443-pvz7dll9	160	24	,	,	,
cord-023443-pvz7dll9	160	25	suggesting	suggest	VBG
cord-023443-pvz7dll9	160	26	no	no	DT
cord-023443-pvz7dll9	160	27	association	association	NN
cord-023443-pvz7dll9	160	28	between	between	IN
cord-023443-pvz7dll9	160	29	malaria	malaria	NN
cord-023443-pvz7dll9	160	30	and	and	CC
cord-023443-pvz7dll9	160	31	the	the	DT
cord-023443-pvz7dll9	160	32	subsequent	subsequent	JJ
cord-023443-pvz7dll9	160	33	development	development	NN
cord-023443-pvz7dll9	160	34	of	of	IN
cord-023443-pvz7dll9	160	35	PEM	PEM	NNP
cord-023443-pvz7dll9	160	36	.	.	.
cord-023443-pvz7dll9	161	1	However	however	RB
cord-023443-pvz7dll9	161	2	,	,	,
cord-023443-pvz7dll9	161	3	we	-PRON-	PRP
cord-023443-pvz7dll9	161	4	found	find	VBD
cord-023443-pvz7dll9	161	5	that	that	IN
cord-023443-pvz7dll9	161	6	age	age	NN
cord-023443-pvz7dll9	161	7	was	be	VBD
cord-023443-pvz7dll9	161	8	acting	act	VBG
cord-023443-pvz7dll9	161	9	as	as	IN
cord-023443-pvz7dll9	161	10	an	an	DT
cord-023443-pvz7dll9	161	11	effect	effect	NN
cord-023443-pvz7dll9	161	12	modifier	modifier	NN
cord-023443-pvz7dll9	161	13	in	in	IN
cord-023443-pvz7dll9	161	14	the	the	DT
cord-023443-pvz7dll9	161	15	association	association	NN
cord-023443-pvz7dll9	161	16	between	between	IN
cord-023443-pvz7dll9	161	17	malaria	malaria	NN
cord-023443-pvz7dll9	161	18	and	and	CC
cord-023443-pvz7dll9	161	19	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	161	20	.	.	.
cord-023443-pvz7dll9	162	1	The	the	DT
cord-023443-pvz7dll9	162	2	IRR	IRR	NNP
cord-023443-pvz7dll9	162	3	for	for	IN
cord-023443-pvz7dll9	162	4	malaria	malaria	NN
cord-023443-pvz7dll9	162	5	in	in	IN
cord-023443-pvz7dll9	162	6	children	child	NNS
cord-023443-pvz7dll9	162	7	0	0	CD
cord-023443-pvz7dll9	162	8	-	-	SYM
cord-023443-pvz7dll9	162	9	2	2	CD
cord-023443-pvz7dll9	162	10	years	year	NNS
cord-023443-pvz7dll9	162	11	old	old	JJ
cord-023443-pvz7dll9	162	12	who	who	WP
cord-023443-pvz7dll9	162	13	were	be	VBD
cord-023443-pvz7dll9	162	14	subsequently	subsequently	RB
cord-023443-pvz7dll9	162	15	characterized	characterize	VBN
cord-023443-pvz7dll9	162	16	as	as	IN
cord-023443-pvz7dll9	162	17	wasted	waste	VBN
cord-023443-pvz7dll9	162	18	was	be	VBD
cord-023443-pvz7dll9	162	19	1.65	1.65	CD
cord-023443-pvz7dll9	162	20	(	(	-LRB-
cord-023443-pvz7dll9	162	21	1.10	1.10	CD
cord-023443-pvz7dll9	162	22	-	-	SYM
cord-023443-pvz7dll9	162	23	2.20	2.20	CD
cord-023443-pvz7dll9	162	24	;	;	.
cord-023443-pvz7dll9	163	1	P	p	NN
cord-023443-pvz7dll9	163	2	¼	¼	CD
cord-023443-pvz7dll9	163	3	0.01	0.01	CD
cord-023443-pvz7dll9	163	4	)	)	-RRB-
cord-023443-pvz7dll9	163	5	,	,	,
cord-023443-pvz7dll9	163	6	and	and	CC
cord-023443-pvz7dll9	164	1	a	a	DT
cord-023443-pvz7dll9	164	2	significant	significant	JJ
cord-023443-pvz7dll9	164	3	overall	overall	JJ
cord-023443-pvz7dll9	164	4	relationship	relationship	NN
cord-023443-pvz7dll9	164	5	between	between	IN
cord-023443-pvz7dll9	164	6	malaria	malaria	NN
cord-023443-pvz7dll9	164	7	and	and	CC
cord-023443-pvz7dll9	164	8	low	low	JJ
cord-023443-pvz7dll9	164	9	-	-	HYPH
cord-023443-pvz7dll9	164	10	HAZ	haz	NN
cord-023443-pvz7dll9	164	11	was	be	VBD
cord-023443-pvz7dll9	164	12	found	find	VBN
cord-023443-pvz7dll9	164	13	on	on	IN
cord-023443-pvz7dll9	164	14	regression	regression	NN
cord-023443-pvz7dll9	164	15	analysis	analysis	NN
cord-023443-pvz7dll9	164	16	when	when	WRB
cord-023443-pvz7dll9	164	17	adjusting	adjust	VBG
cord-023443-pvz7dll9	164	18	for	for	IN
cord-023443-pvz7dll9	164	19	the	the	DT
cord-023443-pvz7dll9	164	20	interaction	interaction	NN
cord-023443-pvz7dll9	164	21	with	with	IN
cord-023443-pvz7dll9	164	22	age	age	NN
cord-023443-pvz7dll9	164	23	(	(	-LRB-
cord-023443-pvz7dll9	164	24	IRR	IRR	NNP
cord-023443-pvz7dll9	164	25	1.89	1.89	CD
cord-023443-pvz7dll9	164	26	;	;	:
cord-023443-pvz7dll9	164	27	1.01	1.01	CD
cord-023443-pvz7dll9	164	28	-	-	HYPH
cord-023443-pvz7dll9	164	29	3.53	3.53	CD
cord-023443-pvz7dll9	164	30	;	;	:
cord-023443-pvz7dll9	164	31	P	p	NN
cord-023443-pvz7dll9	164	32	<	<	XX
cord-023443-pvz7dll9	164	33	0.05	0.05	CD
cord-023443-pvz7dll9	164	34	)	)	-RRB-
cord-023443-pvz7dll9	164	35	.	.	.
cord-023443-pvz7dll9	165	1	Although	although	IN
cord-023443-pvz7dll9	165	2	children	child	NNS
cord-023443-pvz7dll9	165	3	living	live	VBG
cord-023443-pvz7dll9	165	4	on	on	IN
cord-023443-pvz7dll9	165	5	the	the	DT
cord-023443-pvz7dll9	165	6	coast	coast	NN
cord-023443-pvz7dll9	165	7	of	of	IN
cord-023443-pvz7dll9	165	8	Kenya	Kenya	NNP
cord-023443-pvz7dll9	165	9	continue	continue	VBP
cord-023443-pvz7dll9	165	10	to	to	TO
cord-023443-pvz7dll9	165	11	suffer	suffer	VB
cord-023443-pvz7dll9	165	12	clinical	clinical	JJ
cord-023443-pvz7dll9	165	13	episodes	episode	NNS
cord-023443-pvz7dll9	165	14	of	of	IN
cord-023443-pvz7dll9	165	15	uncomplicated	uncomplicated	JJ
cord-023443-pvz7dll9	165	16	malaria	malaria	NN
cord-023443-pvz7dll9	165	17	throughout	throughout	IN
cord-023443-pvz7dll9	165	18	their	-PRON-	PRP$
cord-023443-pvz7dll9	165	19	first	first	JJ
cord-023443-pvz7dll9	165	20	decade	decade	NN
cord-023443-pvz7dll9	165	21	,	,	,
cord-023443-pvz7dll9	165	22	the	the	DT
cord-023443-pvz7dll9	165	23	association	association	NN
cord-023443-pvz7dll9	165	24	between	between	IN
cord-023443-pvz7dll9	165	25	malaria	malaria	NN
cord-023443-pvz7dll9	165	26	and	and	CC
cord-023443-pvz7dll9	165	27	malnutrition	malnutrition	NN
cord-023443-pvz7dll9	165	28	appears	appear	VBZ
cord-023443-pvz7dll9	165	29	to	to	TO
cord-023443-pvz7dll9	165	30	be	be	VB
cord-023443-pvz7dll9	165	31	limited	limit	VBN
cord-023443-pvz7dll9	165	32	to	to	IN
cord-023443-pvz7dll9	165	33	the	the	DT
cord-023443-pvz7dll9	165	34	first	first	JJ
cord-023443-pvz7dll9	165	35	2	2	CD
cord-023443-pvz7dll9	165	36	years	year	NNS
cord-023443-pvz7dll9	165	37	of	of	IN
cord-023443-pvz7dll9	165	38	life	life	NN
cord-023443-pvz7dll9	165	39	.	.	.
cord-023443-pvz7dll9	166	1	A.	A.	NNP
cord-023443-pvz7dll9	166	2	Astrinidou	Astrinidou	NNP
cord-023443-pvz7dll9	166	3	-	-	HYPH
cord-023443-pvz7dll9	166	4	Vakaloudi	Vakaloudi	NNP
cord-023443-pvz7dll9	166	5	,	,	,
cord-023443-pvz7dll9	166	6	1	1	CD
cord-023443-pvz7dll9	166	7	S.	S.	NNP
cord-023443-pvz7dll9	166	8	Xytsas	Xytsas	NNP
cord-023443-pvz7dll9	166	9	,	,	,
cord-023443-pvz7dll9	166	10	1	1	CD
cord-023443-pvz7dll9	166	11	I.	i.	NN
cord-023443-pvz7dll9	166	12	Diamanti	Diamanti	NNP
cord-023443-pvz7dll9	166	13	,	,	,
cord-023443-pvz7dll9	166	14	1	1	CD
cord-023443-pvz7dll9	166	15	H.	H.	NNP
cord-023443-pvz7dll9	166	16	Ioannidis	Ioannidis	NNP
cord-023443-pvz7dll9	166	17	2	2	CD
cord-023443-pvz7dll9	166	18	&	&	CC
cord-023443-pvz7dll9	166	19	P.	P.	NNP
cord-023443-pvz7dll9	166	20	Pangidis	Pangidis	NNP
cord-023443-pvz7dll9	166	21	2	2	CD
cord-023443-pvz7dll9	166	22	1	1	CD
cord-023443-pvz7dll9	166	23	Microbiology	Microbiology	NNP
cord-023443-pvz7dll9	166	24	Department	Department	NNP
cord-023443-pvz7dll9	166	25	of	of	IN
cord-023443-pvz7dll9	166	26	General	General	NNP
cord-023443-pvz7dll9	166	27	Hospital	Hospital	NNP
cord-023443-pvz7dll9	166	28	of	of	IN
cord-023443-pvz7dll9	166	29	Thessaloniki	Thessaloniki	NNP
cord-023443-pvz7dll9	166	30	'	'	POS
cord-023443-pvz7dll9	166	31	Agios	Agios	NNP
cord-023443-pvz7dll9	166	32	Pavlos	Pavlos	NNP
cord-023443-pvz7dll9	166	33	'	'	POS
cord-023443-pvz7dll9	166	34	,	,	,
cord-023443-pvz7dll9	166	35	Thessaloniki	Thessaloniki	NNP
cord-023443-pvz7dll9	166	36	,	,	,
cord-023443-pvz7dll9	166	37	Greece	Greece	NNP
cord-023443-pvz7dll9	166	38	,	,	,
cord-023443-pvz7dll9	166	39	and	and	CC
cord-023443-pvz7dll9	166	40	2	2	CD
cord-023443-pvz7dll9	166	41	Nefrology	Nefrology	NNP
cord-023443-pvz7dll9	166	42	,	,	,
cord-023443-pvz7dll9	166	43	2	2	CD
cord-023443-pvz7dll9	166	44	nd	nd	NNP
cord-023443-pvz7dll9	166	45	IKA	IKA	NNP
cord-023443-pvz7dll9	166	46	Hospital	Hospital	NNP
cord-023443-pvz7dll9	166	47	of	of	IN
cord-023443-pvz7dll9	166	48	Thessaloniki	Thessaloniki	NNP
cord-023443-pvz7dll9	166	49	,	,	,
cord-023443-pvz7dll9	166	50	Thessaloniki	Thessaloniki	NNP
cord-023443-pvz7dll9	166	51	,	,	,
cord-023443-pvz7dll9	166	52	Greece	Greece	NNP
cord-023443-pvz7dll9	166	53	.	.	.
cord-023443-pvz7dll9	167	1	E	e	NN
cord-023443-pvz7dll9	167	2	-	-	NN
cord-023443-pvz7dll9	167	3	mail	mail	NN
cord-023443-pvz7dll9	167	4	:	:	:
cord-023443-pvz7dll9	167	5	stasa@hol.gr	stasa@hol.gr	NNP
cord-023443-pvz7dll9	167	6	Aim	aim	VB
cord-023443-pvz7dll9	167	7	:	:	:
cord-023443-pvz7dll9	167	8	Renal	renal	JJ
cord-023443-pvz7dll9	167	9	dysfunction	dysfunction	NN
cord-023443-pvz7dll9	167	10	may	may	MD
cord-023443-pvz7dll9	167	11	influence	influence	VB
cord-023443-pvz7dll9	167	12	the	the	DT
cord-023443-pvz7dll9	167	13	colonization	colonization	NN
cord-023443-pvz7dll9	167	14	of	of	IN
cord-023443-pvz7dll9	167	15	gastric	gastric	JJ
cord-023443-pvz7dll9	167	16	mucosa	mucosa	NN
cord-023443-pvz7dll9	167	17	by	by	IN
cord-023443-pvz7dll9	167	18	urea	urea	NN
cord-023443-pvz7dll9	167	19	-	-	HYPH
cord-023443-pvz7dll9	167	20	splitting	split	VBG
cord-023443-pvz7dll9	167	21	bacteria	bacteria	NNS
cord-023443-pvz7dll9	167	22	such	such	JJ
cord-023443-pvz7dll9	167	23	as	as	IN
cord-023443-pvz7dll9	167	24	Helicobacter	Helicobacter	NNP
cord-023443-pvz7dll9	167	25	pylori	pylori	NN
cord-023443-pvz7dll9	167	26	,	,	,
cord-023443-pvz7dll9	167	27	by	by	IN
cord-023443-pvz7dll9	167	28	increasing	increase	VBG
cord-023443-pvz7dll9	167	29	urea	urea	NN
cord-023443-pvz7dll9	167	30	concentrations	concentration	NNS
cord-023443-pvz7dll9	167	31	in	in	IN
cord-023443-pvz7dll9	167	32	the	the	DT
cord-023443-pvz7dll9	167	33	gastric	gastric	JJ
cord-023443-pvz7dll9	167	34	juice	juice	NN
cord-023443-pvz7dll9	167	35	.	.	.
cord-023443-pvz7dll9	168	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	168	2	aim	aim	NN
cord-023443-pvz7dll9	168	3	was	be	VBD
cord-023443-pvz7dll9	168	4	to	to	TO
cord-023443-pvz7dll9	168	5	investigate	investigate	VB
cord-023443-pvz7dll9	168	6	the	the	DT
cord-023443-pvz7dll9	168	7	prevalence	prevalence	NN
cord-023443-pvz7dll9	168	8	of	of	IN
cord-023443-pvz7dll9	168	9	H.	h.	NN
cord-023443-pvz7dll9	168	10	pylori	pylori	NN
cord-023443-pvz7dll9	168	11	in	in	IN
cord-023443-pvz7dll9	168	12	patients	patient	NNS
cord-023443-pvz7dll9	168	13	with	with	IN
cord-023443-pvz7dll9	168	14	end	end	NN
cord-023443-pvz7dll9	168	15	-	-	HYPH
cord-023443-pvz7dll9	168	16	stage	stage	NN
cord-023443-pvz7dll9	168	17	renal	renal	JJ
cord-023443-pvz7dll9	168	18	disease	disease	NN
cord-023443-pvz7dll9	168	19	(	(	-LRB-
cord-023443-pvz7dll9	168	20	ESRD	ESRD	NNP
cord-023443-pvz7dll9	168	21	)	)	-RRB-
cord-023443-pvz7dll9	168	22	,	,	,
cord-023443-pvz7dll9	168	23	receiving	receive	VBG
cord-023443-pvz7dll9	168	24	long	long	JJ
cord-023443-pvz7dll9	168	25	-	-	HYPH
cord-023443-pvz7dll9	168	26	term	term	NN
cord-023443-pvz7dll9	168	27	haemodialysis	haemodialysis	NN
cord-023443-pvz7dll9	168	28	treatment	treatment	NN
cord-023443-pvz7dll9	168	29	.	.	.
cord-023443-pvz7dll9	169	1	Methods	method	NNS
cord-023443-pvz7dll9	169	2	:	:	:
cord-023443-pvz7dll9	170	1	This	this	DT
cord-023443-pvz7dll9	170	2	study	study	NN
cord-023443-pvz7dll9	170	3	included	include	VBD
cord-023443-pvz7dll9	170	4	40	40	CD
cord-023443-pvz7dll9	170	5	sera	sera	NNP
cord-023443-pvz7dll9	170	6	from	from	IN
cord-023443-pvz7dll9	170	7	patients	patient	NNS
cord-023443-pvz7dll9	170	8	with	with	IN
cord-023443-pvz7dll9	170	9	ESRD	ESRD	NNP
cord-023443-pvz7dll9	170	10	(	(	-LRB-
cord-023443-pvz7dll9	170	11	29	29	CD
cord-023443-pvz7dll9	170	12	male	male	NN
cord-023443-pvz7dll9	170	13	and	and	CC
cord-023443-pvz7dll9	170	14	11	11	CD
cord-023443-pvz7dll9	170	15	female	female	JJ
cord-023443-pvz7dll9	170	16	)	)	-RRB-
cord-023443-pvz7dll9	170	17	undergoing	undergo	VBG
cord-023443-pvz7dll9	170	18	periodic	periodic	JJ
cord-023443-pvz7dll9	170	19	haemodialysis	haemodialysis	NN
cord-023443-pvz7dll9	170	20	;	;	:
cord-023443-pvz7dll9	170	21	mean	mean	JJ
cord-023443-pvz7dll9	170	22	time	time	NN
cord-023443-pvz7dll9	170	23	of	of	IN
cord-023443-pvz7dll9	170	24	treatment	treatment	NN
cord-023443-pvz7dll9	170	25	was	be	VBD
cord-023443-pvz7dll9	170	26	42.6	42.6	CD
cord-023443-pvz7dll9	170	27	months	month	NNS
cord-023443-pvz7dll9	170	28	.	.	.
cord-023443-pvz7dll9	171	1	Using	use	VBG
cord-023443-pvz7dll9	171	2	ELISA	ELISA	NNP
cord-023443-pvz7dll9	171	3	technique	technique	NN
cord-023443-pvz7dll9	171	4	,	,	,
cord-023443-pvz7dll9	171	5	we	-PRON-	PRP
cord-023443-pvz7dll9	171	6	investigated	investigate	VBD
cord-023443-pvz7dll9	171	7	the	the	DT
cord-023443-pvz7dll9	171	8	presence	presence	NN
cord-023443-pvz7dll9	171	9	of	of	IN
cord-023443-pvz7dll9	171	10	IgG	IgG	NNP
cord-023443-pvz7dll9	171	11	and	and	CC
cord-023443-pvz7dll9	171	12	IgA	IgA	NNP
cord-023443-pvz7dll9	171	13	antibodies	antibody	NNS
cord-023443-pvz7dll9	171	14	against	against	IN
cord-023443-pvz7dll9	171	15	H.	H.	NNP
cord-023443-pvz7dll9	171	16	pylori	pylori	NN
cord-023443-pvz7dll9	171	17	as	as	RB
cord-023443-pvz7dll9	171	18	well	well	RB
cord-023443-pvz7dll9	171	19	as	as	IN
cord-023443-pvz7dll9	171	20	IgG	IgG	NNP
cord-023443-pvz7dll9	171	21	CagA	CagA	NNP
cord-023443-pvz7dll9	171	22	(	(	-LRB-
cord-023443-pvz7dll9	171	23	antibodies	antibody	NNS
cord-023443-pvz7dll9	171	24	specific	specific	JJ
cord-023443-pvz7dll9	171	25	for	for	IN
cord-023443-pvz7dll9	171	26	CagA(þ	CagA(þ	NNS
cord-023443-pvz7dll9	171	27	)	)	-RRB-
cord-023443-pvz7dll9	171	28	strains	strain	NNS
cord-023443-pvz7dll9	171	29	of	of	IN
cord-023443-pvz7dll9	171	30	H.	H.	NNP
cord-023443-pvz7dll9	171	31	pylori	pylori	NN
cord-023443-pvz7dll9	171	32	)	)	-RRB-
cord-023443-pvz7dll9	171	33	.	.	.
cord-023443-pvz7dll9	172	1	Sera	Sera	NNP
cord-023443-pvz7dll9	172	2	from	from	IN
cord-023443-pvz7dll9	172	3	40	40	CD
cord-023443-pvz7dll9	172	4	healthy	healthy	JJ
cord-023443-pvz7dll9	172	5	blood	blood	NN
cord-023443-pvz7dll9	172	6	donors	donor	NNS
cord-023443-pvz7dll9	172	7	were	be	VBD
cord-023443-pvz7dll9	172	8	used	use	VBN
cord-023443-pvz7dll9	172	9	as	as	IN
cord-023443-pvz7dll9	172	10	a	a	DT
cord-023443-pvz7dll9	172	11	control	control	NN
cord-023443-pvz7dll9	172	12	group	group	NN
cord-023443-pvz7dll9	172	13	.	.	.
cord-023443-pvz7dll9	173	1	Results	result	NNS
cord-023443-pvz7dll9	173	2	:	:	:
cord-023443-pvz7dll9	174	1	H.	H.	NNP
cord-023443-pvz7dll9	174	2	pylori	pylori	NNP
cord-023443-pvz7dll9	174	3	IgG	IgG	NNP
cord-023443-pvz7dll9	174	4	antibodies	antibody	NNS
cord-023443-pvz7dll9	174	5	were	be	VBD
cord-023443-pvz7dll9	174	6	detected	detect	VBN
cord-023443-pvz7dll9	174	7	in	in	IN
cord-023443-pvz7dll9	174	8	32	32	CD
cord-023443-pvz7dll9	174	9	out	out	IN
cord-023443-pvz7dll9	174	10	of	of	IN
cord-023443-pvz7dll9	174	11	40	40	CD
cord-023443-pvz7dll9	174	12	(	(	-LRB-
cord-023443-pvz7dll9	174	13	80	80	CD
cord-023443-pvz7dll9	174	14	%	%	NN
cord-023443-pvz7dll9	174	15	)	)	-RRB-
cord-023443-pvz7dll9	174	16	patients	patient	NNS
cord-023443-pvz7dll9	174	17	in	in	IN
cord-023443-pvz7dll9	174	18	the	the	DT
cord-023443-pvz7dll9	174	19	dialysis	dialysis	NN
cord-023443-pvz7dll9	174	20	group	group	NN
cord-023443-pvz7dll9	174	21	,	,	,
cord-023443-pvz7dll9	174	22	while	while	IN
cord-023443-pvz7dll9	174	23	31/40	31/40	CD
cord-023443-pvz7dll9	174	24	(	(	-LRB-
cord-023443-pvz7dll9	174	25	77.5	77.5	CD
cord-023443-pvz7dll9	174	26	%	%	NN
cord-023443-pvz7dll9	174	27	)	)	-RRB-
cord-023443-pvz7dll9	174	28	tested	test	VBD
cord-023443-pvz7dll9	174	29	positive	positive	JJ
cord-023443-pvz7dll9	174	30	for	for	IN
cord-023443-pvz7dll9	175	1	IgA.	IgA.	NNP
cord-023443-pvz7dll9	176	1	IgG	IgG	NNP
cord-023443-pvz7dll9	176	2	CagA	CagA	NNP
cord-023443-pvz7dll9	176	3	antibodies	antibody	NNS
cord-023443-pvz7dll9	176	4	were	be	VBD
cord-023443-pvz7dll9	176	5	present	present	JJ
cord-023443-pvz7dll9	176	6	in	in	IN
cord-023443-pvz7dll9	176	7	13	13	CD
cord-023443-pvz7dll9	176	8	out	out	IN
cord-023443-pvz7dll9	176	9	of	of	IN
cord-023443-pvz7dll9	176	10	40	40	CD
cord-023443-pvz7dll9	176	11	(	(	-LRB-
cord-023443-pvz7dll9	176	12	32.5	32.5	CD
cord-023443-pvz7dll9	176	13	%	%	NN
cord-023443-pvz7dll9	176	14	)	)	-RRB-
cord-023443-pvz7dll9	176	15	.	.	.
cord-023443-pvz7dll9	177	1	Prevalence	prevalence	NN
cord-023443-pvz7dll9	177	2	of	of	IN
cord-023443-pvz7dll9	177	3	H.	H.	NNP
cord-023443-pvz7dll9	177	4	pylori	pylori	NNP
cord-023443-pvz7dll9	177	5	IgG	IgG	NNP
cord-023443-pvz7dll9	177	6	,	,	,
cord-023443-pvz7dll9	177	7	IgA	IgA	NNP
cord-023443-pvz7dll9	177	8	and	and	CC
cord-023443-pvz7dll9	177	9	CagA	CagA	NNP
cord-023443-pvz7dll9	177	10	IgG	IgG	NNP
cord-023443-pvz7dll9	177	11	antibodies	antibody	NNS
cord-023443-pvz7dll9	177	12	in	in	IN
cord-023443-pvz7dll9	177	13	the	the	DT
cord-023443-pvz7dll9	177	14	control	control	NN
cord-023443-pvz7dll9	177	15	group	group	NN
cord-023443-pvz7dll9	177	16	was	be	VBD
cord-023443-pvz7dll9	177	17	33	33	CD
cord-023443-pvz7dll9	177	18	,	,	,
cord-023443-pvz7dll9	177	19	7	7	CD
cord-023443-pvz7dll9	177	20	and	and	CC
cord-023443-pvz7dll9	177	21	15	15	CD
cord-023443-pvz7dll9	177	22	%	%	NN
cord-023443-pvz7dll9	177	23	,	,	,
cord-023443-pvz7dll9	177	24	respectively	respectively	RB
cord-023443-pvz7dll9	177	25	.	.	.
cord-023443-pvz7dll9	178	1	Conclusions	conclusion	NNS
cord-023443-pvz7dll9	178	2	:	:	:
cord-023443-pvz7dll9	179	1	Although	although	IN
cord-023443-pvz7dll9	179	2	international	international	JJ
cord-023443-pvz7dll9	179	3	data	datum	NNS
cord-023443-pvz7dll9	179	4	suggest	suggest	VBP
cord-023443-pvz7dll9	179	5	that	that	IN
cord-023443-pvz7dll9	179	6	prevalence	prevalence	NN
cord-023443-pvz7dll9	179	7	of	of	IN
cord-023443-pvz7dll9	179	8	H.	h.	NN
cord-023443-pvz7dll9	179	9	pylori	pylori	NN
cord-023443-pvz7dll9	179	10	infection	infection	NN
cord-023443-pvz7dll9	179	11	is	be	VBZ
cord-023443-pvz7dll9	179	12	the	the	DT
cord-023443-pvz7dll9	179	13	same	same	JJ
cord-023443-pvz7dll9	179	14	in	in	IN
cord-023443-pvz7dll9	179	15	ESRD	ESRD	NNP
cord-023443-pvz7dll9	179	16	patients	patient	NNS
cord-023443-pvz7dll9	179	17	as	as	IN
cord-023443-pvz7dll9	179	18	in	in	IN
cord-023443-pvz7dll9	179	19	healthy	healthy	JJ
cord-023443-pvz7dll9	179	20	individuals	individual	NNS
cord-023443-pvz7dll9	179	21	,	,	,
cord-023443-pvz7dll9	179	22	in	in	IN
cord-023443-pvz7dll9	179	23	our	-PRON-	PRP$
cord-023443-pvz7dll9	179	24	study	study	NN
cord-023443-pvz7dll9	179	25	that	that	WDT
cord-023443-pvz7dll9	179	26	seems	seem	VBZ
cord-023443-pvz7dll9	179	27	not	not	RB
cord-023443-pvz7dll9	179	28	to	to	TO
cord-023443-pvz7dll9	179	29	be	be	VB
cord-023443-pvz7dll9	179	30	the	the	DT
cord-023443-pvz7dll9	179	31	case	case	NN
cord-023443-pvz7dll9	179	32	.	.	.
cord-023443-pvz7dll9	180	1	The	the	DT
cord-023443-pvz7dll9	180	2	higher	high	JJR
cord-023443-pvz7dll9	180	3	blood	blood	NN
cord-023443-pvz7dll9	180	4	and	and	CC
cord-023443-pvz7dll9	180	5	gastric	gastric	JJ
cord-023443-pvz7dll9	180	6	juice	juice	NN
cord-023443-pvz7dll9	180	7	urea	urea	NN
cord-023443-pvz7dll9	180	8	levels	level	NNS
cord-023443-pvz7dll9	180	9	may	may	MD
cord-023443-pvz7dll9	180	10	be	be	VB
cord-023443-pvz7dll9	180	11	a	a	DT
cord-023443-pvz7dll9	180	12	risk	risk	NN
cord-023443-pvz7dll9	180	13	factor	factor	NN
cord-023443-pvz7dll9	180	14	(	(	-LRB-
cord-023443-pvz7dll9	180	15	among	among	IN
cord-023443-pvz7dll9	180	16	many	many	JJ
cord-023443-pvz7dll9	180	17	others	other	NNS
cord-023443-pvz7dll9	180	18	)	)	-RRB-
cord-023443-pvz7dll9	180	19	,	,	,
cord-023443-pvz7dll9	180	20	but	but	CC
cord-023443-pvz7dll9	180	21	more	more	JJR
cord-023443-pvz7dll9	180	22	studies	study	NNS
cord-023443-pvz7dll9	180	23	are	be	VBP
cord-023443-pvz7dll9	180	24	required	require	VBN
cord-023443-pvz7dll9	180	25	in	in	IN
cord-023443-pvz7dll9	180	26	order	order	NN
cord-023443-pvz7dll9	180	27	to	to	TO
cord-023443-pvz7dll9	180	28	understand	understand	VB
cord-023443-pvz7dll9	180	29	the	the	DT
cord-023443-pvz7dll9	180	30	relation	relation	NN
cord-023443-pvz7dll9	180	31	of	of	IN
cord-023443-pvz7dll9	180	32	H.	H.	NNP
cord-023443-pvz7dll9	180	33	pylori	pylori	NN
cord-023443-pvz7dll9	180	34	infection	infection	NN
cord-023443-pvz7dll9	180	35	in	in	IN
cord-023443-pvz7dll9	180	36	this	this	DT
cord-023443-pvz7dll9	180	37	group	group	NN
cord-023443-pvz7dll9	180	38	of	of	IN
cord-023443-pvz7dll9	180	39	patients	patient	NNS
cord-023443-pvz7dll9	180	40	.	.	.
cord-023443-pvz7dll9	181	1	Flanders	Flanders	NNP
cord-023443-pvz7dll9	181	2	Interuniversity	Interuniversity	NNP
cord-023443-pvz7dll9	181	3	Institute	Institute	NNP
cord-023443-pvz7dll9	181	4	for	for	IN
cord-023443-pvz7dll9	181	5	Biotechnology	Biotechnology	NNP
cord-023443-pvz7dll9	181	6	,	,	,
cord-023443-pvz7dll9	181	7	Department	Department	NNP
cord-023443-pvz7dll9	181	8	of	of	IN
cord-023443-pvz7dll9	181	9	Molecular	Molecular	NNP
cord-023443-pvz7dll9	181	10	and	and	CC
cord-023443-pvz7dll9	181	11	Cellular	Cellular	NNP
cord-023443-pvz7dll9	181	12	Interactions	Interactions	NNPS
cord-023443-pvz7dll9	181	13	,	,	,
cord-023443-pvz7dll9	181	14	Free	Free	NNP
cord-023443-pvz7dll9	181	15	University	University	NNP
cord-023443-pvz7dll9	181	16	of	of	IN
cord-023443-pvz7dll9	181	17	Brussels	Brussels	NNP
cord-023443-pvz7dll9	181	18	,	,	,
cord-023443-pvz7dll9	181	19	Brussels	Brussels	NNP
cord-023443-pvz7dll9	181	20	,	,	,
cord-023443-pvz7dll9	181	21	and	and	CC
cord-023443-pvz7dll9	181	22	2	2	CD
cord-023443-pvz7dll9	181	23	Pasteur	Pasteur	NNP
cord-023443-pvz7dll9	181	24	Institute	Institute	NNP
cord-023443-pvz7dll9	181	25	of	of	IN
cord-023443-pvz7dll9	181	26	Brussels	Brussels	NNP
cord-023443-pvz7dll9	181	27	,	,	,
cord-023443-pvz7dll9	181	28	Mycobacterial	Mycobacterial	NNP
cord-023443-pvz7dll9	181	29	Immunology	Immunology	NNP
cord-023443-pvz7dll9	181	30	,	,	,
cord-023443-pvz7dll9	181	31	Brussels	Brussels	NNP
cord-023443-pvz7dll9	181	32	,	,	,
cord-023443-pvz7dll9	181	33	Belgium	Belgium	NNP
cord-023443-pvz7dll9	181	34	.	.	.
cord-023443-pvz7dll9	182	1	E	e	NN
cord-023443-pvz7dll9	182	2	-	-	NN
cord-023443-pvz7dll9	182	3	mail	mail	NN
cord-023443-pvz7dll9	182	4	:	:	:
cord-023443-pvz7dll9	182	5	tgartner@vub.ac.be	tgartner@vub.ac.be	ADD
cord-023443-pvz7dll9	182	6	Immunity	immunity	NN
cord-023443-pvz7dll9	182	7	against	against	IN
cord-023443-pvz7dll9	182	8	tuberculosis	tuberculosis	NN
cord-023443-pvz7dll9	182	9	(	(	-LRB-
cord-023443-pvz7dll9	182	10	TB	TB	NNP
cord-023443-pvz7dll9	182	11	)	)	-RRB-
cord-023443-pvz7dll9	182	12	,	,	,
cord-023443-pvz7dll9	182	13	caused	cause	VBN
cord-023443-pvz7dll9	182	14	by	by	IN
cord-023443-pvz7dll9	182	15	Mycobacterium	Mycobacterium	NNP
cord-023443-pvz7dll9	182	16	tuberculosis	tuberculosis	NN
cord-023443-pvz7dll9	182	17	,	,	,
cord-023443-pvz7dll9	182	18	depends	depend	VBZ
cord-023443-pvz7dll9	182	19	largely	largely	RB
cord-023443-pvz7dll9	182	20	on	on	IN
cord-023443-pvz7dll9	182	21	activation	activation	NN
cord-023443-pvz7dll9	182	22	and	and	CC
cord-023443-pvz7dll9	182	23	maintenance	maintenance	NN
cord-023443-pvz7dll9	182	24	of	of	IN
cord-023443-pvz7dll9	182	25	strong	strong	JJ
cord-023443-pvz7dll9	182	26	cell	cell	NN
cord-023443-pvz7dll9	182	27	-	-	HYPH
cord-023443-pvz7dll9	182	28	mediated	mediate	VBN
cord-023443-pvz7dll9	182	29	immune	immune	JJ
cord-023443-pvz7dll9	182	30	responses	response	NNS
cord-023443-pvz7dll9	182	31	involving	involve	VBG
cord-023443-pvz7dll9	182	32	both	both	CC
cord-023443-pvz7dll9	182	33	CD4	CD4	NNP
cord-023443-pvz7dll9	182	34	þ	þ	NNP
cord-023443-pvz7dll9	182	35	and	and	CC
cord-023443-pvz7dll9	182	36	CD8	CD8	NNP
cord-023443-pvz7dll9	182	37	þ	þ	NNP
cord-023443-pvz7dll9	182	38	T	T	NNP
cord-023443-pvz7dll9	182	39	cells	cell	NNS
cord-023443-pvz7dll9	182	40	and	and	CC
cord-023443-pvz7dll9	182	41	the	the	DT
cord-023443-pvz7dll9	182	42	ability	ability	NN
cord-023443-pvz7dll9	182	43	to	to	TO
cord-023443-pvz7dll9	182	44	respond	respond	VB
cord-023443-pvz7dll9	182	45	with	with	IN
cord-023443-pvz7dll9	182	46	Th1-type	Th1-type	NNP
cord-023443-pvz7dll9	182	47	cytokines	cytokine	NNS
cord-023443-pvz7dll9	182	48	,	,	,
cord-023443-pvz7dll9	182	49	particularly	particularly	RB
cord-023443-pvz7dll9	182	50	IFN	IFN	NNP
cord-023443-pvz7dll9	182	51	-	-	HYPH
cord-023443-pvz7dll9	182	52	g	g	NNP
cord-023443-pvz7dll9	182	53	.	.	.
cord-023443-pvz7dll9	183	1	Recent	recent	JJ
cord-023443-pvz7dll9	183	2	studies	study	NNS
cord-023443-pvz7dll9	183	3	suggested	suggest	VBD
cord-023443-pvz7dll9	183	4	that	that	IN
cord-023443-pvz7dll9	183	5	BCG	BCG	NNP
cord-023443-pvz7dll9	183	6	,	,	,
cord-023443-pvz7dll9	183	7	the	the	DT
cord-023443-pvz7dll9	183	8	only	only	JJ
cord-023443-pvz7dll9	183	9	licensed	licensed	JJ
cord-023443-pvz7dll9	183	10	vaccine	vaccine	NN
cord-023443-pvz7dll9	183	11	against	against	IN
cord-023443-pvz7dll9	183	12	M.	M.	NNP
cord-023443-pvz7dll9	183	13	tuberculosis	tuberculosis	NN
cord-023443-pvz7dll9	183	14	,	,	,
cord-023443-pvz7dll9	183	15	may	may	MD
cord-023443-pvz7dll9	183	16	fail	fail	VB
cord-023443-pvz7dll9	183	17	to	to	TO
cord-023443-pvz7dll9	183	18	induce	induce	VB
cord-023443-pvz7dll9	183	19	T	t	NN
cord-023443-pvz7dll9	183	20	-	-	HYPH
cord-023443-pvz7dll9	183	21	cell	cell	NN
cord-023443-pvz7dll9	183	22	responses	response	NNS
cord-023443-pvz7dll9	183	23	in	in	IN
cord-023443-pvz7dll9	183	24	the	the	DT
cord-023443-pvz7dll9	183	25	lung	lung	NN
cord-023443-pvz7dll9	183	26	mucosa	mucosa	NN
cord-023443-pvz7dll9	183	27	and	and	CC
cord-023443-pvz7dll9	183	28	may	may	MD
cord-023443-pvz7dll9	183	29	therefore	therefore	RB
cord-023443-pvz7dll9	183	30	not	not	RB
cord-023443-pvz7dll9	183	31	protect	protect	VB
cord-023443-pvz7dll9	183	32	against	against	IN
cord-023443-pvz7dll9	183	33	pulmonary	pulmonary	JJ
cord-023443-pvz7dll9	183	34	TB	tb	NN
cord-023443-pvz7dll9	183	35	.	.	.
cord-023443-pvz7dll9	184	1	A	a	DT
cord-023443-pvz7dll9	184	2	decrease	decrease	NN
cord-023443-pvz7dll9	184	3	in	in	IN
cord-023443-pvz7dll9	184	4	TB	TB	NNP
cord-023443-pvz7dll9	184	5	mortality	mortality	NN
cord-023443-pvz7dll9	184	6	may	may	MD
cord-023443-pvz7dll9	184	7	be	be	VB
cord-023443-pvz7dll9	184	8	achieved	achieve	VBN
cord-023443-pvz7dll9	184	9	by	by	IN
cord-023443-pvz7dll9	184	10	enhancing	enhance	VBG
cord-023443-pvz7dll9	184	11	immunity	immunity	NN
cord-023443-pvz7dll9	184	12	in	in	IN
cord-023443-pvz7dll9	184	13	the	the	DT
cord-023443-pvz7dll9	184	14	lung	lung	NN
cord-023443-pvz7dll9	184	15	.	.	.
cord-023443-pvz7dll9	185	1	The	the	DT
cord-023443-pvz7dll9	185	2	present	present	JJ
cord-023443-pvz7dll9	185	3	study	study	NN
cord-023443-pvz7dll9	185	4	evaluated	evaluate	VBD
cord-023443-pvz7dll9	185	5	the	the	DT
cord-023443-pvz7dll9	185	6	induction	induction	NN
cord-023443-pvz7dll9	185	7	of	of	IN
cord-023443-pvz7dll9	185	8	antigen	antigen	NN
cord-023443-pvz7dll9	185	9	-	-	HYPH
cord-023443-pvz7dll9	185	10	specific	specific	JJ
cord-023443-pvz7dll9	185	11	immunity	immunity	NN
cord-023443-pvz7dll9	185	12	in	in	IN
cord-023443-pvz7dll9	185	13	the	the	DT
cord-023443-pvz7dll9	185	14	lung	lung	NN
cord-023443-pvz7dll9	185	15	by	by	IN
cord-023443-pvz7dll9	185	16	intranasal	intranasal	NN
cord-023443-pvz7dll9	185	17	(	(	-LRB-
cord-023443-pvz7dll9	185	18	i.n	i.n	NNP
cord-023443-pvz7dll9	185	19	.	.	NNP
cord-023443-pvz7dll9	185	20	)	)	-RRB-
cord-023443-pvz7dll9	185	21	delivery	delivery	NN
cord-023443-pvz7dll9	185	22	of	of	IN
cord-023443-pvz7dll9	185	23	the	the	DT
cord-023443-pvz7dll9	185	24	lipoprotein	lipoprotein	NN
cord-023443-pvz7dll9	186	1	I	-PRON-	PRP
cord-023443-pvz7dll9	186	2	(	(	-LRB-
cord-023443-pvz7dll9	186	3	OprI	OprI	NNP
cord-023443-pvz7dll9	186	4	)	)	-RRB-
cord-023443-pvz7dll9	186	5	from	from	IN
cord-023443-pvz7dll9	186	6	Pseudomonas	Pseudomonas	NNP
cord-023443-pvz7dll9	186	7	aeruginosa	aeruginosa	NN
cord-023443-pvz7dll9	186	8	.	.	.
cord-023443-pvz7dll9	187	1	OprI	OprI	NNP
cord-023443-pvz7dll9	187	2	has	have	VBZ
cord-023443-pvz7dll9	187	3	shown	show	VBN
cord-023443-pvz7dll9	187	4	to	to	TO
cord-023443-pvz7dll9	187	5	be	be	VB
cord-023443-pvz7dll9	187	6	a	a	DT
cord-023443-pvz7dll9	187	7	Toll	toll	NN
cord-023443-pvz7dll9	187	8	-	-	HYPH
cord-023443-pvz7dll9	187	9	like	like	JJ
cord-023443-pvz7dll9	187	10	receptor	receptor	NN
cord-023443-pvz7dll9	187	11	2/4	2/4	CD
cord-023443-pvz7dll9	187	12	agonist	agonist	NN
cord-023443-pvz7dll9	187	13	that	that	WDT
cord-023443-pvz7dll9	187	14	,	,	,
cord-023443-pvz7dll9	187	15	when	when	WRB
cord-023443-pvz7dll9	187	16	given	give	VBN
cord-023443-pvz7dll9	187	17	subcutaneously	subcutaneously	RB
cord-023443-pvz7dll9	187	18	,	,	,
cord-023443-pvz7dll9	187	19	induces	induce	VBZ
cord-023443-pvz7dll9	187	20	Type-1	type-1	NN
cord-023443-pvz7dll9	187	21	immune	immune	JJ
cord-023443-pvz7dll9	187	22	responses	response	NNS
cord-023443-pvz7dll9	187	23	against	against	IN
cord-023443-pvz7dll9	187	24	heterologous	heterologous	JJ
cord-023443-pvz7dll9	187	25	antigens	antigen	NNS
cord-023443-pvz7dll9	187	26	.	.	.
cord-023443-pvz7dll9	188	1	Here	here	RB
cord-023443-pvz7dll9	188	2	,	,	,
cord-023443-pvz7dll9	188	3	a	a	DT
cord-023443-pvz7dll9	188	4	fusion	fusion	NN
cord-023443-pvz7dll9	188	5	of	of	IN
cord-023443-pvz7dll9	188	6	OprI	OprI	NNP
cord-023443-pvz7dll9	188	7	to	to	TO
cord-023443-pvz7dll9	188	8	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	188	9	of	of	IN
cord-023443-pvz7dll9	188	10	Mtb	Mtb	NNP
cord-023443-pvz7dll9	188	11	(	(	-LRB-
cord-023443-pvz7dll9	188	12	OprI	OprI	NNP
cord-023443-pvz7dll9	188	13	-	-	HYPH
cord-023443-pvz7dll9	188	14	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	188	15	)	)	-RRB-
cord-023443-pvz7dll9	188	16	was	be	VBD
cord-023443-pvz7dll9	188	17	used	use	VBN
cord-023443-pvz7dll9	188	18	as	as	IN
cord-023443-pvz7dll9	188	19	a	a	DT
cord-023443-pvz7dll9	188	20	subunit	subunit	NN
cord-023443-pvz7dll9	188	21	vaccine	vaccine	NN
cord-023443-pvz7dll9	188	22	in	in	IN
cord-023443-pvz7dll9	188	23	homologous	homologous	JJ
cord-023443-pvz7dll9	188	24	prime	prime	JJ
cord-023443-pvz7dll9	188	25	-	-	HYPH
cord-023443-pvz7dll9	188	26	boost	boost	NN
cord-023443-pvz7dll9	188	27	immunizations	immunization	NNS
cord-023443-pvz7dll9	188	28	.	.	.
cord-023443-pvz7dll9	189	1	In	in	IN
cord-023443-pvz7dll9	189	2	addition	addition	NN
cord-023443-pvz7dll9	189	3	,	,	,
cord-023443-pvz7dll9	189	4	OprI	OprI	NNP
cord-023443-pvz7dll9	189	5	-	-	HYPH
cord-023443-pvz7dll9	189	6	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	189	7	was	be	VBD
cord-023443-pvz7dll9	189	8	combined	combine	VBN
cord-023443-pvz7dll9	189	9	with	with	IN
cord-023443-pvz7dll9	189	10	an	an	DT
cord-023443-pvz7dll9	189	11	Ag85A	ag85a	NN
cord-023443-pvz7dll9	189	12	-	-	HYPH
cord-023443-pvz7dll9	189	13	encoding	encode	VBG
cord-023443-pvz7dll9	189	14	DNA	dna	NN
cord-023443-pvz7dll9	189	15	vaccine	vaccine	NN
cord-023443-pvz7dll9	189	16	(	(	-LRB-
cord-023443-pvz7dll9	189	17	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	189	18	DNA	DNA	NNP
cord-023443-pvz7dll9	189	19	)	)	-RRB-
cord-023443-pvz7dll9	189	20	or	or	CC
cord-023443-pvz7dll9	189	21	with	with	IN
cord-023443-pvz7dll9	189	22	BCG	BCG	NNP
cord-023443-pvz7dll9	189	23	in	in	IN
cord-023443-pvz7dll9	189	24	heterologous	heterologous	JJ
cord-023443-pvz7dll9	189	25	prime	prime	JJ
cord-023443-pvz7dll9	189	26	-	-	HYPH
cord-023443-pvz7dll9	189	27	boost	boost	NN
cord-023443-pvz7dll9	189	28	vaccinations	vaccination	NNS
cord-023443-pvz7dll9	189	29	.	.	.
cord-023443-pvz7dll9	190	1	Intranasal	intranasal	NN
cord-023443-pvz7dll9	190	2	and	and	CC
cord-023443-pvz7dll9	190	3	parenteral	parenteral	JJ
cord-023443-pvz7dll9	190	4	delivery	delivery	NN
cord-023443-pvz7dll9	190	5	with	with	IN
cord-023443-pvz7dll9	190	6	OprI	OprI	NNP
cord-023443-pvz7dll9	190	7	-	-	HYPH
cord-023443-pvz7dll9	190	8	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	190	9	elicited	elicit	VBD
cord-023443-pvz7dll9	190	10	comparable	comparable	JJ
cord-023443-pvz7dll9	190	11	T	t	NN
cord-023443-pvz7dll9	190	12	-	-	HYPH
cord-023443-pvz7dll9	190	13	cell	cell	NN
cord-023443-pvz7dll9	190	14	responses	response	NNS
cord-023443-pvz7dll9	190	15	in	in	IN
cord-023443-pvz7dll9	190	16	the	the	DT
cord-023443-pvz7dll9	190	17	spleen	spleen	NN
cord-023443-pvz7dll9	190	18	;	;	:
cord-023443-pvz7dll9	190	19	in	in	IN
cord-023443-pvz7dll9	190	20	addition	addition	NN
cord-023443-pvz7dll9	190	21	,	,	,
cord-023443-pvz7dll9	190	22	i.n	i.n	NNP
cord-023443-pvz7dll9	190	23	.	.	NNP
cord-023443-pvz7dll9	190	24	delivery	delivery	NN
cord-023443-pvz7dll9	190	25	elicited	elicit	VBD
cord-023443-pvz7dll9	190	26	specific	specific	JJ
cord-023443-pvz7dll9	190	27	T	t	NN
cord-023443-pvz7dll9	190	28	-	-	HYPH
cord-023443-pvz7dll9	190	29	cell	cell	NN
cord-023443-pvz7dll9	190	30	responses	response	NNS
cord-023443-pvz7dll9	190	31	in	in	IN
cord-023443-pvz7dll9	190	32	the	the	DT
cord-023443-pvz7dll9	190	33	lung	lung	NN
cord-023443-pvz7dll9	190	34	lymph	lymph	NN
cord-023443-pvz7dll9	190	35	nodes	node	NNS
cord-023443-pvz7dll9	190	36	(	(	-LRB-
cord-023443-pvz7dll9	190	37	LLNs	lln	NNS
cord-023443-pvz7dll9	190	38	)	)	-RRB-
cord-023443-pvz7dll9	190	39	.	.	.
cord-023443-pvz7dll9	191	1	Intramuscular	intramuscular	JJ
cord-023443-pvz7dll9	191	2	delivery	delivery	NN
cord-023443-pvz7dll9	191	3	of	of	IN
cord-023443-pvz7dll9	191	4	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	191	5	DNA	DNA	NNP
cord-023443-pvz7dll9	191	6	induced	induce	VBD
cord-023443-pvz7dll9	191	7	significant	significant	JJ
cord-023443-pvz7dll9	191	8	systemic	systemic	JJ
cord-023443-pvz7dll9	191	9	Th1	th1	CD
cord-023443-pvz7dll9	191	10	immune	immune	JJ
cord-023443-pvz7dll9	191	11	responses	response	NNS
cord-023443-pvz7dll9	191	12	.	.	.
cord-023443-pvz7dll9	192	1	Intranasal	intranasal	NN
cord-023443-pvz7dll9	192	2	boosting	boost	VBG
cord-023443-pvz7dll9	192	3	with	with	IN
cord-023443-pvz7dll9	192	4	OprI	OprI	NNP
cord-023443-pvz7dll9	192	5	-	-	HYPH
cord-023443-pvz7dll9	192	6	Ag85A	Ag85A	NNP
cord-023443-pvz7dll9	192	7	enhanced	enhance	VBD
cord-023443-pvz7dll9	192	8	this	this	DT
cord-023443-pvz7dll9	192	9	response	response	NN
cord-023443-pvz7dll9	192	10	and	and	CC
cord-023443-pvz7dll9	192	11	in	in	IN
cord-023443-pvz7dll9	192	12	addition	addition	NN
cord-023443-pvz7dll9	192	13	induced	induce	VBD
cord-023443-pvz7dll9	192	14	an	an	DT
cord-023443-pvz7dll9	192	15	antigen	antigen	NN
cord-023443-pvz7dll9	192	16	-	-	HYPH
cord-023443-pvz7dll9	192	17	specific	specific	JJ
cord-023443-pvz7dll9	192	18	IFN	IFN	NNP
cord-023443-pvz7dll9	192	19	-	-	HYPH
cord-023443-pvz7dll9	192	20	g	g	NN
cord-023443-pvz7dll9	192	21	response	response	NN
cord-023443-pvz7dll9	192	22	in	in	IN
cord-023443-pvz7dll9	192	23	LLN	LLN	NNP
cord-023443-pvz7dll9	192	24	.	.	.
cord-023443-pvz7dll9	193	1	OprI	OprI	NNP
cord-023443-pvz7dll9	193	2	may	may	MD
cord-023443-pvz7dll9	193	3	therefore	therefore	RB
cord-023443-pvz7dll9	193	4	be	be	VB
cord-023443-pvz7dll9	193	5	an	an	DT
cord-023443-pvz7dll9	193	6	efficient	efficient	JJ
cord-023443-pvz7dll9	193	7	adjuvant	adjuvant	NN
cord-023443-pvz7dll9	193	8	for	for	IN
cord-023443-pvz7dll9	193	9	mucosal	mucosal	JJ
cord-023443-pvz7dll9	193	10	boosting	boosting	NN
cord-023443-pvz7dll9	193	11	.	.	.
cord-023443-pvz7dll9	194	1	We	-PRON-	PRP
cord-023443-pvz7dll9	194	2	continue	continue	VBP
cord-023443-pvz7dll9	194	3	to	to	TO
cord-023443-pvz7dll9	194	4	evaluate	evaluate	VB
cord-023443-pvz7dll9	194	5	the	the	DT
cord-023443-pvz7dll9	194	6	protection	protection	NN
cord-023443-pvz7dll9	194	7	induced	induce	VBN
cord-023443-pvz7dll9	194	8	by	by	IN
cord-023443-pvz7dll9	194	9	OprI	OprI	NNP
cord-023443-pvz7dll9	194	10	-	-	HYPH
cord-023443-pvz7dll9	194	11	based	base	VBN
cord-023443-pvz7dll9	194	12	prime	prime	JJ
cord-023443-pvz7dll9	194	13	-	-	HYPH
cord-023443-pvz7dll9	194	14	boost	boost	NN
cord-023443-pvz7dll9	194	15	vaccinations	vaccination	NNS
cord-023443-pvz7dll9	194	16	against	against	IN
cord-023443-pvz7dll9	194	17	pulmonary	pulmonary	JJ
cord-023443-pvz7dll9	194	18	TB	TB	NNP
cord-023443-pvz7dll9	194	19	.	.	.
cord-023443-pvz7dll9	195	1	Results	result	NNS
cord-023443-pvz7dll9	195	2	on	on	IN
cord-023443-pvz7dll9	195	3	the	the	DT
cord-023443-pvz7dll9	195	4	immunogenicity	immunogenicity	NN
cord-023443-pvz7dll9	195	5	and	and	CC
cord-023443-pvz7dll9	195	6	protection	protection	NN
cord-023443-pvz7dll9	195	7	against	against	IN
cord-023443-pvz7dll9	195	8	intravenous	intravenous	JJ
cord-023443-pvz7dll9	195	9	Mtb	Mtb	NNP
cord-023443-pvz7dll9	195	10	H37Rv	H37Rv	NNP
cord-023443-pvz7dll9	195	11	infection	infection	NN
cord-023443-pvz7dll9	195	12	will	will	MD
cord-023443-pvz7dll9	195	13	be	be	VB
cord-023443-pvz7dll9	195	14	presented	present	VBN
cord-023443-pvz7dll9	195	15	.	.	.
cord-023443-pvz7dll9	196	1	Toll	toll	NN
cord-023443-pvz7dll9	196	2	-	-	HYPH
cord-023443-pvz7dll9	196	3	like	like	JJ
cord-023443-pvz7dll9	196	4	receptors	receptor	NNS
cord-023443-pvz7dll9	196	5	(	(	-LRB-
cord-023443-pvz7dll9	196	6	TLRs	TLRs	NNP
cord-023443-pvz7dll9	196	7	)	)	-RRB-
cord-023443-pvz7dll9	196	8	are	be	VBP
cord-023443-pvz7dll9	196	9	pattern	pattern	NN
cord-023443-pvz7dll9	196	10	recognition	recognition	NN
cord-023443-pvz7dll9	196	11	receptors	receptor	NNS
cord-023443-pvz7dll9	196	12	of	of	IN
cord-023443-pvz7dll9	196	13	the	the	DT
cord-023443-pvz7dll9	196	14	innate	innate	JJ
cord-023443-pvz7dll9	196	15	immune	immune	JJ
cord-023443-pvz7dll9	196	16	system	system	NN
cord-023443-pvz7dll9	196	17	,	,	,
cord-023443-pvz7dll9	196	18	which	which	WDT
cord-023443-pvz7dll9	196	19	recognize	recognize	VBP
cord-023443-pvz7dll9	196	20	molecular	molecular	JJ
cord-023443-pvz7dll9	196	21	structures	structure	NNS
cord-023443-pvz7dll9	196	22	on	on	IN
cord-023443-pvz7dll9	196	23	pathogens	pathogen	NNS
cord-023443-pvz7dll9	196	24	or	or	CC
cord-023443-pvz7dll9	196	25	cellular	cellular	JJ
cord-023443-pvz7dll9	196	26	stress	stress	NN
cord-023443-pvz7dll9	196	27	-	-	HYPH
cord-023443-pvz7dll9	196	28	associated	associate	VBN
cord-023443-pvz7dll9	196	29	molecules	molecule	NNS
cord-023443-pvz7dll9	196	30	.	.	.
cord-023443-pvz7dll9	197	1	TLR	TLR	NNP
cord-023443-pvz7dll9	197	2	-	-	HYPH
cord-023443-pvz7dll9	197	3	ligand	ligand	NN
cord-023443-pvz7dll9	197	4	interactions	interaction	NNS
cord-023443-pvz7dll9	197	5	trigger	trigger	VBP
cord-023443-pvz7dll9	197	6	activation	activation	NN
cord-023443-pvz7dll9	197	7	of	of	IN
cord-023443-pvz7dll9	197	8	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	197	9	signal	signal	NN
cord-023443-pvz7dll9	197	10	transduction	transduction	NN
cord-023443-pvz7dll9	197	11	and	and	CC
cord-023443-pvz7dll9	197	12	expression	expression	NN
cord-023443-pvz7dll9	197	13	of	of	IN
cord-023443-pvz7dll9	197	14	genes	gene	NNS
cord-023443-pvz7dll9	197	15	involved	involve	VBN
cord-023443-pvz7dll9	197	16	in	in	IN
cord-023443-pvz7dll9	197	17	host	host	NN
cord-023443-pvz7dll9	197	18	defense	defense	NN
cord-023443-pvz7dll9	197	19	.	.	.
cord-023443-pvz7dll9	198	1	In	in	IN
cord-023443-pvz7dll9	198	2	this	this	DT
cord-023443-pvz7dll9	198	3	study	study	NN
cord-023443-pvz7dll9	198	4	,	,	,
cord-023443-pvz7dll9	198	5	we	-PRON-	PRP
cord-023443-pvz7dll9	198	6	have	have	VBP
cord-023443-pvz7dll9	198	7	examined	examine	VBN
cord-023443-pvz7dll9	198	8	the	the	DT
cord-023443-pvz7dll9	198	9	requirement	requirement	NN
cord-023443-pvz7dll9	198	10	for	for	IN
cord-023443-pvz7dll9	198	11	different	different	JJ
cord-023443-pvz7dll9	198	12	TLR	TLR	NNP
cord-023443-pvz7dll9	198	13	adaptor	adaptor	NN
cord-023443-pvz7dll9	198	14	molecules	molecule	NNS
cord-023443-pvz7dll9	198	15	in	in	IN
cord-023443-pvz7dll9	198	16	virus	virus	NN
cord-023443-pvz7dll9	198	17	-	-	HYPH
cord-023443-pvz7dll9	198	18	induced	induce	VBN
cord-023443-pvz7dll9	198	19	chemokine	chemokine	NN
cord-023443-pvz7dll9	198	20	expression	expression	NN
cord-023443-pvz7dll9	198	21	and	and	CC
cord-023443-pvz7dll9	198	22	are	be	VBP
cord-023443-pvz7dll9	198	23	currently	currently	RB
cord-023443-pvz7dll9	198	24	trying	try	VBG
cord-023443-pvz7dll9	198	25	to	to	TO
cord-023443-pvz7dll9	198	26	identify	identify	VB
cord-023443-pvz7dll9	198	27	the	the	DT
cord-023443-pvz7dll9	198	28	TLR	TLR	NNP
cord-023443-pvz7dll9	198	29	involved	involve	VBN
cord-023443-pvz7dll9	198	30	.	.	.
cord-023443-pvz7dll9	199	1	We	-PRON-	PRP
cord-023443-pvz7dll9	199	2	have	have	VBP
cord-023443-pvz7dll9	199	3	found	find	VBN
cord-023443-pvz7dll9	199	4	that	that	IN
cord-023443-pvz7dll9	199	5	both	both	CC
cord-023443-pvz7dll9	199	6	a	a	DT
cord-023443-pvz7dll9	199	7	herpesvirus	herpesvirus	NN
cord-023443-pvz7dll9	199	8	[	[	-LRB-
cord-023443-pvz7dll9	199	9	herpes	herpes	NN
cord-023443-pvz7dll9	199	10	simplex	simplex	NN
cord-023443-pvz7dll9	199	11	virus	virus	NN
cord-023443-pvz7dll9	199	12	(	(	-LRB-
cord-023443-pvz7dll9	199	13	HSV	HSV	NNP
cord-023443-pvz7dll9	199	14	)	)	-RRB-
cord-023443-pvz7dll9	199	15	]	]	-RRB-
cord-023443-pvz7dll9	199	16	and	and	CC
cord-023443-pvz7dll9	199	17	a	a	DT
cord-023443-pvz7dll9	199	18	paramyxovirus	paramyxovirus	JJ
cord-023443-pvz7dll9	199	19	(	(	-LRB-
cord-023443-pvz7dll9	199	20	Sendai	Sendai	NNP
cord-023443-pvz7dll9	199	21	virus	virus	NN
cord-023443-pvz7dll9	199	22	)	)	-RRB-
cord-023443-pvz7dll9	199	23	require	require	VBP
cord-023443-pvz7dll9	199	24	a	a	DT
cord-023443-pvz7dll9	199	25	functional	functional	JJ
cord-023443-pvz7dll9	199	26	genome	genome	NN
cord-023443-pvz7dll9	199	27	to	to	TO
cord-023443-pvz7dll9	199	28	induce	induce	VB
cord-023443-pvz7dll9	199	29	expression	expression	NN
cord-023443-pvz7dll9	199	30	or	or	CC
cord-023443-pvz7dll9	199	31	proinflammatory	proinflammatory	JJ
cord-023443-pvz7dll9	199	32	chemokines	chemokine	NNS
cord-023443-pvz7dll9	199	33	in	in	IN
cord-023443-pvz7dll9	199	34	human	human	JJ
cord-023443-pvz7dll9	199	35	and	and	CC
cord-023443-pvz7dll9	199	36	murine	murine	JJ
cord-023443-pvz7dll9	199	37	monocytic	monocytic	JJ
cord-023443-pvz7dll9	199	38	cell	cell	NN
cord-023443-pvz7dll9	199	39	lines	line	NNS
cord-023443-pvz7dll9	199	40	.	.	.
cord-023443-pvz7dll9	200	1	For	for	IN
cord-023443-pvz7dll9	200	2	both	both	DT
cord-023443-pvz7dll9	200	3	viruses	virus	NNS
cord-023443-pvz7dll9	200	4	,	,	,
cord-023443-pvz7dll9	200	5	this	this	DT
cord-023443-pvz7dll9	200	6	is	be	VBZ
cord-023443-pvz7dll9	200	7	independent	independent	JJ
cord-023443-pvz7dll9	200	8	of	of	IN
cord-023443-pvz7dll9	200	9	the	the	DT
cord-023443-pvz7dll9	200	10	TLR	TLR	NNP
cord-023443-pvz7dll9	200	11	adaptor	adaptor	NN
cord-023443-pvz7dll9	200	12	molecules	molecule	NNS
cord-023443-pvz7dll9	201	1	TRIF	TRIF	NNP
cord-023443-pvz7dll9	201	2	and	and	CC
cord-023443-pvz7dll9	201	3	Mal	Mal	NNP
cord-023443-pvz7dll9	201	4	.	.	.
cord-023443-pvz7dll9	202	1	However	however	RB
cord-023443-pvz7dll9	202	2	,	,	,
cord-023443-pvz7dll9	202	3	overexpression	overexpression	NN
cord-023443-pvz7dll9	202	4	of	of	IN
cord-023443-pvz7dll9	202	5	the	the	DT
cord-023443-pvz7dll9	202	6	Vaccinia	Vaccinia	NNP
cord-023443-pvz7dll9	202	7	virus	virus	NN
cord-023443-pvz7dll9	202	8	-	-	HYPH
cord-023443-pvz7dll9	202	9	encoded	encode	VBN
cord-023443-pvz7dll9	202	10	inhibitor	inhibitor	NN
cord-023443-pvz7dll9	202	11	of	of	IN
cord-023443-pvz7dll9	202	12	TLR	TLR	NNP
cord-023443-pvz7dll9	202	13	-	-	HYPH
cord-023443-pvz7dll9	202	14	signalling	signal	VBG
cord-023443-pvz7dll9	202	15	A52R	a52r	NN
cord-023443-pvz7dll9	202	16	or	or	CC
cord-023443-pvz7dll9	202	17	dominant	dominant	JJ
cord-023443-pvz7dll9	202	18	-	-	HYPH
cord-023443-pvz7dll9	202	19	negative	negative	JJ
cord-023443-pvz7dll9	202	20	MyD88	MyD88	NNS
cord-023443-pvz7dll9	202	21	totally	totally	RB
cord-023443-pvz7dll9	202	22	inhibited	inhibited	JJ
cord-023443-pvz7dll9	202	23	HSV	HSV	NNP
cord-023443-pvz7dll9	202	24	-	-	HYPH
cord-023443-pvz7dll9	202	25	induced	induce	VBN
cord-023443-pvz7dll9	202	26	RANTES	RANTES	NNP
cord-023443-pvz7dll9	202	27	expression	expression	NN
cord-023443-pvz7dll9	202	28	but	but	CC
cord-023443-pvz7dll9	202	29	only	only	RB
cord-023443-pvz7dll9	202	30	partially	partially	RB
cord-023443-pvz7dll9	202	31	prevented	prevent	VBD
cord-023443-pvz7dll9	202	32	Sendai	Sendai	NNP
cord-023443-pvz7dll9	202	33	virus	virus	NN
cord-023443-pvz7dll9	202	34	from	from	IN
cord-023443-pvz7dll9	202	35	inducing	induce	VBG
cord-023443-pvz7dll9	202	36	this	this	DT
cord-023443-pvz7dll9	202	37	chemokine	chemokine	NN
cord-023443-pvz7dll9	202	38	.	.	.
cord-023443-pvz7dll9	203	1	This	this	DT
cord-023443-pvz7dll9	203	2	suggests	suggest	VBZ
cord-023443-pvz7dll9	203	3	that	that	IN
cord-023443-pvz7dll9	203	4	HSV	HSV	NNP
cord-023443-pvz7dll9	203	5	-	-	HYPH
cord-023443-pvz7dll9	203	6	induced	induce	VBN
cord-023443-pvz7dll9	203	7	RANTES	RANTES	NNP
cord-023443-pvz7dll9	203	8	expression	expression	NN
cord-023443-pvz7dll9	203	9	occurs	occur	VBZ
cord-023443-pvz7dll9	203	10	via	via	IN
cord-023443-pvz7dll9	203	11	a	a	DT
cord-023443-pvz7dll9	203	12	TLR	TLR	NNP
cord-023443-pvz7dll9	203	13	pathways	pathway	NNS
cord-023443-pvz7dll9	203	14	,	,	,
cord-023443-pvz7dll9	203	15	whereas	whereas	IN
cord-023443-pvz7dll9	203	16	Sendai	Sendai	NNP
cord-023443-pvz7dll9	203	17	virus	virus	NN
cord-023443-pvz7dll9	203	18	utilizes	utilize	VBZ
cord-023443-pvz7dll9	203	19	both	both	DT
cord-023443-pvz7dll9	203	20	TLR	TLR	NNP
cord-023443-pvz7dll9	203	21	-	-	HYPH
cord-023443-pvz7dll9	203	22	dependent	dependent	JJ
cord-023443-pvz7dll9	203	23	and	and	CC
cord-023443-pvz7dll9	203	24	-independent	-independent	JJ
cord-023443-pvz7dll9	203	25	pathways	pathway	NNS
cord-023443-pvz7dll9	203	26	to	to	TO
cord-023443-pvz7dll9	203	27	stimulate	stimulate	VB
cord-023443-pvz7dll9	203	28	expression	expression	NN
cord-023443-pvz7dll9	203	29	of	of	IN
cord-023443-pvz7dll9	203	30	RANTES	rante	NNS
cord-023443-pvz7dll9	203	31	.	.	.
cord-023443-pvz7dll9	204	1	We	-PRON-	PRP
cord-023443-pvz7dll9	204	2	are	be	VBP
cord-023443-pvz7dll9	204	3	currently	currently	RB
cord-023443-pvz7dll9	204	4	trying	try	VBG
cord-023443-pvz7dll9	204	5	to	to	TO
cord-023443-pvz7dll9	204	6	identify	identify	VB
cord-023443-pvz7dll9	204	7	the	the	DT
cord-023443-pvz7dll9	204	8	TLRs	tlr	NNS
cord-023443-pvz7dll9	204	9	involved	involve	VBN
cord-023443-pvz7dll9	204	10	.	.	.
cord-023443-pvz7dll9	205	1	Data	datum	NNS
cord-023443-pvz7dll9	205	2	from	from	IN
cord-023443-pvz7dll9	205	3	these	these	DT
cord-023443-pvz7dll9	205	4	studies	study	NNS
cord-023443-pvz7dll9	205	5	will	will	MD
cord-023443-pvz7dll9	205	6	also	also	RB
cord-023443-pvz7dll9	205	7	be	be	VB
cord-023443-pvz7dll9	205	8	presented	present	VBN
cord-023443-pvz7dll9	205	9	at	at	IN
cord-023443-pvz7dll9	205	10	the	the	DT
cord-023443-pvz7dll9	205	11	meeting	meeting	NN
cord-023443-pvz7dll9	205	12	.	.	.
cord-023443-pvz7dll9	206	1	2	2	LS
cord-023443-pvz7dll9	206	2	0	0	CD
cord-023443-pvz7dll9	206	3	-5	-5	CD
cord-023443-pvz7dll9	206	4	0	0	CD
cord-023443-pvz7dll9	207	1	-oligoadenylate	-oligoadenylate	.
cord-023443-pvz7dll9	208	1	synthetases	synthetase	NNS
cord-023443-pvz7dll9	208	2	are	be	VBP
cord-023443-pvz7dll9	208	3	interferon	interferon	NN
cord-023443-pvz7dll9	208	4	-	-	HYPH
cord-023443-pvz7dll9	208	5	induced	induce	VBN
cord-023443-pvz7dll9	208	6	,	,	,
cord-023443-pvz7dll9	208	7	double	double	RB
cord-023443-pvz7dll9	208	8	-	-	HYPH
cord-023443-pvz7dll9	208	9	stranded	strand	VBN
cord-023443-pvz7dll9	208	10	RNA	RNA	NNP
cord-023443-pvz7dll9	208	11	-	-	HYPH
cord-023443-pvz7dll9	208	12	activated	activate	VBN
cord-023443-pvz7dll9	208	13	antiviral	antiviral	JJ
cord-023443-pvz7dll9	208	14	enzymes	enzyme	NNS
cord-023443-pvz7dll9	208	15	which	which	WDT
cord-023443-pvz7dll9	208	16	are	be	VBP
cord-023443-pvz7dll9	208	17	the	the	DT
cord-023443-pvz7dll9	208	18	only	only	JJ
cord-023443-pvz7dll9	208	19	proteins	protein	NNS
cord-023443-pvz7dll9	208	20	known	know	VBN
cord-023443-pvz7dll9	208	21	to	to	TO
cord-023443-pvz7dll9	208	22	catalyse	catalyse	VB
cord-023443-pvz7dll9	208	23	2	2	CD
cord-023443-pvz7dll9	208	24	0	0	CD
cord-023443-pvz7dll9	208	25	-specific	-specific	NN
cord-023443-pvz7dll9	208	26	nucleotidyl	nucleotidyl	NN
cord-023443-pvz7dll9	208	27	transfer	transfer	NN
cord-023443-pvz7dll9	208	28	.	.	.
cord-023443-pvz7dll9	209	1	This	this	DT
cord-023443-pvz7dll9	209	2	first	first	JJ
cord-023443-pvz7dll9	209	3	crystal	crystal	NN
cord-023443-pvz7dll9	209	4	structure	structure	NN
cord-023443-pvz7dll9	209	5	of	of	IN
cord-023443-pvz7dll9	209	6	a	a	DT
cord-023443-pvz7dll9	209	7	2	2	CD
cord-023443-pvz7dll9	209	8	0	0	CD
cord-023443-pvz7dll9	209	9	-5	-5	CD
cord-023443-pvz7dll9	209	10	0oligoadenylate	0oligoadenylate	CD
cord-023443-pvz7dll9	209	11	synthetase	synthetase	NNP
cord-023443-pvz7dll9	209	12	reveals	reveal	VBZ
cord-023443-pvz7dll9	209	13	a	a	DT
cord-023443-pvz7dll9	209	14	structural	structural	JJ
cord-023443-pvz7dll9	209	15	conservation	conservation	NN
cord-023443-pvz7dll9	209	16	with	with	IN
cord-023443-pvz7dll9	209	17	the	the	DT
cord-023443-pvz7dll9	209	18	3	3	CD
cord-023443-pvz7dll9	209	19	0	0	CD
cord-023443-pvz7dll9	209	20	-specific	-specific	NN
cord-023443-pvz7dll9	209	21	poly(A	poly(A	NNP
cord-023443-pvz7dll9	209	22	)	)	-RRB-
cord-023443-pvz7dll9	209	23	polymerase	polymerase	NN
cord-023443-pvz7dll9	209	24	that	that	WDT
cord-023443-pvz7dll9	209	25	,	,	,
cord-023443-pvz7dll9	209	26	coupled	couple	VBN
cord-023443-pvz7dll9	209	27	with	with	IN
cord-023443-pvz7dll9	209	28	structure	structure	NN
cord-023443-pvz7dll9	209	29	-	-	HYPH
cord-023443-pvz7dll9	209	30	guided	guide	VBN
cord-023443-pvz7dll9	209	31	mutagenesis	mutagenesis	NN
cord-023443-pvz7dll9	209	32	,	,	,
cord-023443-pvz7dll9	209	33	supports	support	VBZ
cord-023443-pvz7dll9	209	34	a	a	DT
cord-023443-pvz7dll9	209	35	conserved	conserved	JJ
cord-023443-pvz7dll9	209	36	catalytic	catalytic	JJ
cord-023443-pvz7dll9	209	37	mechanism	mechanism	NN
cord-023443-pvz7dll9	209	38	for	for	IN
cord-023443-pvz7dll9	209	39	the	the	DT
cord-023443-pvz7dll9	209	40	2	2	CD
cord-023443-pvz7dll9	209	41	0	0	CD
cord-023443-pvz7dll9	209	42	-and	-and	SYM
cord-023443-pvz7dll9	209	43	3	3	CD
cord-023443-pvz7dll9	209	44	0	0	CD
cord-023443-pvz7dll9	209	45	-specific	-specific	HYPH
cord-023443-pvz7dll9	209	46	nucleotidyl	nucleotidyl	NN
cord-023443-pvz7dll9	209	47	transferases	transferase	NNS
cord-023443-pvz7dll9	209	48	.	.	.
cord-023443-pvz7dll9	210	1	Comparison	comparison	NN
cord-023443-pvz7dll9	210	2	with	with	IN
cord-023443-pvz7dll9	210	3	structures	structure	NNS
cord-023443-pvz7dll9	210	4	of	of	IN
cord-023443-pvz7dll9	210	5	other	other	JJ
cord-023443-pvz7dll9	210	6	superfamily	superfamily	NN
cord-023443-pvz7dll9	210	7	members	member	NNS
cord-023443-pvz7dll9	210	8	indicates	indicate	VBZ
cord-023443-pvz7dll9	210	9	that	that	IN
cord-023443-pvz7dll9	210	10	the	the	DT
cord-023443-pvz7dll9	210	11	donor	donor	NN
cord-023443-pvz7dll9	210	12	substrates	substrate	NNS
cord-023443-pvz7dll9	210	13	are	be	VBP
cord-023443-pvz7dll9	210	14	bound	bind	VBN
cord-023443-pvz7dll9	210	15	by	by	IN
cord-023443-pvz7dll9	210	16	conserved	conserve	VBN
cord-023443-pvz7dll9	210	17	active	active	JJ
cord-023443-pvz7dll9	210	18	site	site	NN
cord-023443-pvz7dll9	210	19	features	feature	NNS
cord-023443-pvz7dll9	210	20	while	while	IN
cord-023443-pvz7dll9	210	21	the	the	DT
cord-023443-pvz7dll9	210	22	acceptor	acceptor	NN
cord-023443-pvz7dll9	210	23	substrates	substrate	NNS
cord-023443-pvz7dll9	210	24	are	be	VBP
cord-023443-pvz7dll9	210	25	oriented	orient	VBN
cord-023443-pvz7dll9	210	26	by	by	IN
cord-023443-pvz7dll9	210	27	nonconserved	nonconserved	JJ
cord-023443-pvz7dll9	210	28	regions	region	NNS
cord-023443-pvz7dll9	210	29	.	.	.
cord-023443-pvz7dll9	211	1	The	the	DT
cord-023443-pvz7dll9	211	2	2	2	CD
cord-023443-pvz7dll9	211	3	0	0	CD
cord-023443-pvz7dll9	211	4	-5	-5	NNP
cord-023443-pvz7dll9	211	5	0oligoadenylate	0oligoadenylate	CD
cord-023443-pvz7dll9	211	6	synthetases	synthetase	NNS
cord-023443-pvz7dll9	211	7	are	be	VBP
cord-023443-pvz7dll9	211	8	activated	activate	VBN
cord-023443-pvz7dll9	211	9	by	by	IN
cord-023443-pvz7dll9	211	10	viral	viral	JJ
cord-023443-pvz7dll9	211	11	doublestranded	doublestranded	NNP
cord-023443-pvz7dll9	211	12	RNA	RNA	NNP
cord-023443-pvz7dll9	211	13	in	in	IN
cord-023443-pvz7dll9	211	14	infected	infected	JJ
cord-023443-pvz7dll9	211	15	cells	cell	NNS
cord-023443-pvz7dll9	211	16	and	and	CC
cord-023443-pvz7dll9	211	17	initiate	initiate	VB
cord-023443-pvz7dll9	211	18	a	a	DT
cord-023443-pvz7dll9	211	19	cellular	cellular	JJ
cord-023443-pvz7dll9	211	20	response	response	NN
cord-023443-pvz7dll9	211	21	by	by	IN
cord-023443-pvz7dll9	211	22	synthesizing	synthesize	VBG
cord-023443-pvz7dll9	211	23	2	2	CD
cord-023443-pvz7dll9	211	24	0	0	CD
cord-023443-pvz7dll9	211	25	-5	-5	CD
cord-023443-pvz7dll9	211	26	0	0	CD
cord-023443-pvz7dll9	211	27	-oligoadenylates	-oligoadenylate	NNS
cord-023443-pvz7dll9	211	28	,	,	,
cord-023443-pvz7dll9	211	29	that	that	IN
cord-023443-pvz7dll9	211	30	in	in	IN
cord-023443-pvz7dll9	211	31	turn	turn	NN
cord-023443-pvz7dll9	211	32	activate	activate	VBP
cord-023443-pvz7dll9	211	33	RNase	RNase	NNP
cord-023443-pvz7dll9	211	34	L.	L.	NNP
cord-023443-pvz7dll9	212	1	This	this	DT
cord-023443-pvz7dll9	212	2	crystal	crystal	NN
cord-023443-pvz7dll9	212	3	structure	structure	NN
cord-023443-pvz7dll9	212	4	suggests	suggest	VBZ
cord-023443-pvz7dll9	212	5	that	that	IN
cord-023443-pvz7dll9	212	6	activation	activation	NN
cord-023443-pvz7dll9	212	7	involves	involve	VBZ
cord-023443-pvz7dll9	212	8	a	a	DT
cord-023443-pvz7dll9	212	9	domain	domain	NN
cord-023443-pvz7dll9	212	10	-	-	HYPH
cord-023443-pvz7dll9	212	11	domain	domain	NN
cord-023443-pvz7dll9	212	12	shift	shift	NN
cord-023443-pvz7dll9	212	13	and	and	CC
cord-023443-pvz7dll9	212	14	identifies	identify	VBZ
cord-023443-pvz7dll9	212	15	a	a	DT
cord-023443-pvz7dll9	212	16	putative	putative	JJ
cord-023443-pvz7dll9	212	17	dsRNA	dsrna	NN
cord-023443-pvz7dll9	212	18	activation	activation	NN
cord-023443-pvz7dll9	212	19	site	site	NN
cord-023443-pvz7dll9	212	20	that	that	WDT
cord-023443-pvz7dll9	212	21	is	be	VBZ
cord-023443-pvz7dll9	212	22	probed	probe	VBN
cord-023443-pvz7dll9	212	23	by	by	IN
cord-023443-pvz7dll9	212	24	mutagenesis	mutagenesis	NN
cord-023443-pvz7dll9	212	25	.	.	.
cord-023443-pvz7dll9	213	1	We	-PRON-	PRP
cord-023443-pvz7dll9	213	2	demonstrated	demonstrate	VBD
cord-023443-pvz7dll9	213	3	that	that	IN
cord-023443-pvz7dll9	213	4	this	this	DT
cord-023443-pvz7dll9	213	5	site	site	NN
cord-023443-pvz7dll9	213	6	is	be	VBZ
cord-023443-pvz7dll9	213	7	required	require	VBN
cord-023443-pvz7dll9	213	8	both	both	CC
cord-023443-pvz7dll9	213	9	for	for	IN
cord-023443-pvz7dll9	213	10	the	the	DT
cord-023443-pvz7dll9	213	11	binding	binding	NN
cord-023443-pvz7dll9	213	12	of	of	IN
cord-023443-pvz7dll9	213	13	dsRNA	dsrna	NN
cord-023443-pvz7dll9	213	14	and	and	CC
cord-023443-pvz7dll9	213	15	for	for	IN
cord-023443-pvz7dll9	213	16	the	the	DT
cord-023443-pvz7dll9	213	17	subsequent	subsequent	JJ
cord-023443-pvz7dll9	213	18	activation	activation	NN
cord-023443-pvz7dll9	213	19	of	of	IN
cord-023443-pvz7dll9	213	20	OAS	OAS	NNP
cord-023443-pvz7dll9	213	21	.	.	.
cord-023443-pvz7dll9	214	1	This	this	DT
cord-023443-pvz7dll9	214	2	RNA	rna	NN
cord-023443-pvz7dll9	214	3	-	-	HYPH
cord-023443-pvz7dll9	214	4	binding	bind	VBG
cord-023443-pvz7dll9	214	5	site	site	NN
cord-023443-pvz7dll9	214	6	is	be	VBZ
cord-023443-pvz7dll9	214	7	different	different	JJ
cord-023443-pvz7dll9	214	8	from	from	IN
cord-023443-pvz7dll9	214	9	known	know	VBN
cord-023443-pvz7dll9	214	10	RNA	rna	NN
cord-023443-pvz7dll9	214	11	-	-	HYPH
cord-023443-pvz7dll9	214	12	binding	bind	VBG
cord-023443-pvz7dll9	214	13	site	site	NN
cord-023443-pvz7dll9	214	14	;	;	:
cord-023443-pvz7dll9	214	15	rather	rather	RB
cord-023443-pvz7dll9	214	16	than	than	IN
cord-023443-pvz7dll9	214	17	forming	form	VBG
cord-023443-pvz7dll9	214	18	a	a	DT
cord-023443-pvz7dll9	214	19	defined	define	VBN
cord-023443-pvz7dll9	214	20	three	three	CD
cord-023443-pvz7dll9	214	21	-	-	HYPH
cord-023443-pvz7dll9	214	22	dimensional	dimensional	JJ
cord-023443-pvz7dll9	214	23	domain	domain	NN
cord-023443-pvz7dll9	214	24	,	,	,
cord-023443-pvz7dll9	214	25	it	-PRON-	PRP
cord-023443-pvz7dll9	214	26	is	be	VBZ
cord-023443-pvz7dll9	214	27	located	locate	VBN
cord-023443-pvz7dll9	214	28	at	at	IN
cord-023443-pvz7dll9	214	29	the	the	DT
cord-023443-pvz7dll9	214	30	interface	interface	NN
cord-023443-pvz7dll9	214	31	of	of	IN
cord-023443-pvz7dll9	214	32	the	the	DT
cord-023443-pvz7dll9	214	33	two	two	CD
cord-023443-pvz7dll9	214	34	major	major	JJ
cord-023443-pvz7dll9	214	35	domains	domain	NNS
cord-023443-pvz7dll9	214	36	in	in	IN
cord-023443-pvz7dll9	214	37	OAS	OAS	NNP
cord-023443-pvz7dll9	214	38	.	.	.
cord-023443-pvz7dll9	215	1	This	this	DT
cord-023443-pvz7dll9	215	2	novel	novel	NN
cord-023443-pvz7dll9	215	3	architecture	architecture	NN
cord-023443-pvz7dll9	215	4	ensures	ensure	VBZ
cord-023443-pvz7dll9	215	5	that	that	IN
cord-023443-pvz7dll9	215	6	the	the	DT
cord-023443-pvz7dll9	215	7	dsRNA	dsrna	NN
cord-023443-pvz7dll9	215	8	helix	helix	NN
cord-023443-pvz7dll9	215	9	can	can	MD
cord-023443-pvz7dll9	215	10	make	make	VB
cord-023443-pvz7dll9	215	11	simultaneously	simultaneously	RB
cord-023443-pvz7dll9	215	12	contact	contact	VB
cord-023443-pvz7dll9	215	13	with	with	IN
cord-023443-pvz7dll9	215	14	both	both	DT
cord-023443-pvz7dll9	215	15	domains	domain	NNS
cord-023443-pvz7dll9	215	16	of	of	IN
cord-023443-pvz7dll9	215	17	OAS	OAS	NNP
cord-023443-pvz7dll9	215	18	and	and	CC
cord-023443-pvz7dll9	215	19	ensure	ensure	VB
cord-023443-pvz7dll9	215	20	the	the	DT
cord-023443-pvz7dll9	215	21	subsequent	subsequent	JJ
cord-023443-pvz7dll9	215	22	structural	structural	JJ
cord-023443-pvz7dll9	215	23	rearrangement	rearrangement	NN
cord-023443-pvz7dll9	215	24	leading	lead	VBG
cord-023443-pvz7dll9	215	25	to	to	IN
cord-023443-pvz7dll9	215	26	the	the	DT
cord-023443-pvz7dll9	215	27	activation	activation	NN
cord-023443-pvz7dll9	215	28	of	of	IN
cord-023443-pvz7dll9	215	29	OAS	OAS	NNP
cord-023443-pvz7dll9	215	30	.	.	.
cord-023443-pvz7dll9	216	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	216	2	work	work	NN
cord-023443-pvz7dll9	216	3	provides	provide	VBZ
cord-023443-pvz7dll9	216	4	structural	structural	JJ
cord-023443-pvz7dll9	216	5	insight	insight	NN
cord-023443-pvz7dll9	216	6	into	into	IN
cord-023443-pvz7dll9	216	7	cellular	cellular	JJ
cord-023443-pvz7dll9	216	8	recognition	recognition	NN
cord-023443-pvz7dll9	216	9	of	of	IN
cord-023443-pvz7dll9	216	10	double	double	RB
cord-023443-pvz7dll9	216	11	-	-	HYPH
cord-023443-pvz7dll9	216	12	stranded	strand	VBN
cord-023443-pvz7dll9	216	13	RNA	RNA	NNP
cord-023443-pvz7dll9	216	14	of	of	IN
cord-023443-pvz7dll9	216	15	viral	viral	JJ
cord-023443-pvz7dll9	216	16	origin	origin	NN
cord-023443-pvz7dll9	216	17	and	and	CC
cord-023443-pvz7dll9	216	18	identifies	identify	VBZ
cord-023443-pvz7dll9	216	19	a	a	DT
cord-023443-pvz7dll9	216	20	novel	novel	JJ
cord-023443-pvz7dll9	216	21	RNA	rna	NN
cord-023443-pvz7dll9	216	22	-	-	HYPH
cord-023443-pvz7dll9	216	23	binding	bind	VBG
cord-023443-pvz7dll9	216	24	motif	motif	NN
cord-023443-pvz7dll9	216	25	.	.	.
cord-023443-pvz7dll9	217	1	Bacteria	Bacteria	NNS
cord-023443-pvz7dll9	217	2	-	-	HYPH
cord-023443-pvz7dll9	217	3	specific	specific	JJ
cord-023443-pvz7dll9	217	4	IgA	IgA	NNP
cord-023443-pvz7dll9	217	5	antibodies	antibody	NNS
cord-023443-pvz7dll9	217	6	are	be	VBP
cord-023443-pvz7dll9	217	7	efficient	efficient	JJ
cord-023443-pvz7dll9	217	8	opsonins	opsonin	NNS
cord-023443-pvz7dll9	217	9	for	for	IN
cord-023443-pvz7dll9	217	10	neutrophils	neutrophil	NNS
cord-023443-pvz7dll9	217	11	and	and	CC
cord-023443-pvz7dll9	217	12	mononuclear	mononuclear	JJ
cord-023443-pvz7dll9	217	13	phagocytes	phagocyte	NNS
cord-023443-pvz7dll9	217	14	,	,	,
cord-023443-pvz7dll9	217	15	provided	provide	VBD
cord-023443-pvz7dll9	217	16	that	that	IN
cord-023443-pvz7dll9	217	17	the	the	DT
cord-023443-pvz7dll9	217	18	phagocytes	phagocyte	NNS
cord-023443-pvz7dll9	217	19	express	express	VBP
cord-023443-pvz7dll9	217	20	the	the	DT
cord-023443-pvz7dll9	217	21	Fca	Fca	NNP
cord-023443-pvz7dll9	217	22	receptor	receptor	NN
cord-023443-pvz7dll9	217	23	(	(	-LRB-
cord-023443-pvz7dll9	217	24	CD89	CD89	NNP
cord-023443-pvz7dll9	217	25	)	)	-RRB-
cord-023443-pvz7dll9	217	26	.	.	.
cord-023443-pvz7dll9	218	1	Expression	expression	NN
cord-023443-pvz7dll9	218	2	of	of	IN
cord-023443-pvz7dll9	218	3	CD89	CD89	NNP
cord-023443-pvz7dll9	218	4	can	can	MD
cord-023443-pvz7dll9	218	5	be	be	VB
cord-023443-pvz7dll9	218	6	stimulated	stimulate	VBN
cord-023443-pvz7dll9	218	7	by	by	IN
cord-023443-pvz7dll9	218	8	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	218	9	cytokines	cytokine	NNS
cord-023443-pvz7dll9	218	10	,	,	,
cord-023443-pvz7dll9	218	11	activated	activate	VBN
cord-023443-pvz7dll9	218	12	complement	complement	NN
cord-023443-pvz7dll9	218	13	factors	factor	NNS
cord-023443-pvz7dll9	218	14	and	and	CC
cord-023443-pvz7dll9	218	15	certain	certain	JJ
cord-023443-pvz7dll9	218	16	microbial	microbial	JJ
cord-023443-pvz7dll9	218	17	components	component	NNS
cord-023443-pvz7dll9	218	18	.	.	.
cord-023443-pvz7dll9	219	1	In	in	IN
cord-023443-pvz7dll9	219	2	one	one	CD
cord-023443-pvz7dll9	219	3	study	study	NN
cord-023443-pvz7dll9	219	4	,	,	,
cord-023443-pvz7dll9	219	5	unstimulated	unstimulated	JJ
cord-023443-pvz7dll9	219	6	phagocytes	phagocyte	NNS
cord-023443-pvz7dll9	219	7	were	be	VBD
cord-023443-pvz7dll9	219	8	able	able	JJ
cord-023443-pvz7dll9	219	9	to	to	TO
cord-023443-pvz7dll9	219	10	ingest	ingest	VB
cord-023443-pvz7dll9	219	11	IgA	IgA	NNP
cord-023443-pvz7dll9	219	12	antibody	antibody	NN
cord-023443-pvz7dll9	219	13	-	-	HYPH
cord-023443-pvz7dll9	219	14	treated	treat	VBN
cord-023443-pvz7dll9	219	15	pneumococci	pneumococci	NN
cord-023443-pvz7dll9	219	16	,	,	,
cord-023443-pvz7dll9	219	17	but	but	CC
cord-023443-pvz7dll9	219	18	only	only	RB
cord-023443-pvz7dll9	219	19	in	in	IN
cord-023443-pvz7dll9	219	20	the	the	DT
cord-023443-pvz7dll9	219	21	presence	presence	NN
cord-023443-pvz7dll9	219	22	of	of	IN
cord-023443-pvz7dll9	219	23	complement	complement	NN
cord-023443-pvz7dll9	219	24	,	,	,
cord-023443-pvz7dll9	219	25	which	which	WDT
cord-023443-pvz7dll9	219	26	was	be	VBD
cord-023443-pvz7dll9	219	27	found	find	VBN
cord-023443-pvz7dll9	219	28	to	to	TO
cord-023443-pvz7dll9	219	29	be	be	VB
cord-023443-pvz7dll9	219	30	activated	activate	VBN
cord-023443-pvz7dll9	219	31	by	by	IN
cord-023443-pvz7dll9	219	32	the	the	DT
cord-023443-pvz7dll9	219	33	IgA	IgA	NNP
cord-023443-pvz7dll9	219	34	antibodies	antibody	NNS
cord-023443-pvz7dll9	219	35	along	along	IN
cord-023443-pvz7dll9	219	36	the	the	DT
cord-023443-pvz7dll9	219	37	alternative	alternative	JJ
cord-023443-pvz7dll9	219	38	pathway	pathway	NN
cord-023443-pvz7dll9	219	39	.	.	.
cord-023443-pvz7dll9	220	1	Pneumococci	pneumococcus	NNS
cord-023443-pvz7dll9	220	2	produce	produce	VBP
cord-023443-pvz7dll9	220	3	IgA1	iga1	PRP
cord-023443-pvz7dll9	220	4	protease	protease	NN
cord-023443-pvz7dll9	220	5	that	that	WDT
cord-023443-pvz7dll9	220	6	cleaves	cleave	VBZ
cord-023443-pvz7dll9	220	7	human	human	JJ
cord-023443-pvz7dll9	220	8	IgA1	IgA1	NNP
cord-023443-pvz7dll9	220	9	,	,	,
cord-023443-pvz7dll9	220	10	but	but	CC
cord-023443-pvz7dll9	220	11	not	not	RB
cord-023443-pvz7dll9	220	12	IgA2	IgA2	VBN
cord-023443-pvz7dll9	220	13	,	,	,
cord-023443-pvz7dll9	220	14	molecules	molecule	NNS
cord-023443-pvz7dll9	220	15	in	in	IN
cord-023443-pvz7dll9	220	16	the	the	DT
cord-023443-pvz7dll9	220	17	hinge	hinge	NN
cord-023443-pvz7dll9	220	18	region	region	NN
cord-023443-pvz7dll9	220	19	.	.	.
cord-023443-pvz7dll9	221	1	This	this	DT
cord-023443-pvz7dll9	221	2	leaves	leave	VBZ
cord-023443-pvz7dll9	221	3	IgA1	iga1	PRP
cord-023443-pvz7dll9	221	4	as	as	IN
cord-023443-pvz7dll9	221	5	Faba	Faba	NNP
cord-023443-pvz7dll9	221	6	(	(	-LRB-
cord-023443-pvz7dll9	221	7	monovalent	monovalent	NN
cord-023443-pvz7dll9	221	8	)	)	-RRB-
cord-023443-pvz7dll9	221	9	deprived	deprive	VBN
cord-023443-pvz7dll9	221	10	of	of	IN
cord-023443-pvz7dll9	221	11	Fca	Fca	NNP
cord-023443-pvz7dll9	221	12	which	which	WDT
cord-023443-pvz7dll9	221	13	contains	contain	VBZ
cord-023443-pvz7dll9	221	14	the	the	DT
cord-023443-pvz7dll9	221	15	docking	docking	NN
cord-023443-pvz7dll9	221	16	site	site	NN
cord-023443-pvz7dll9	221	17	for	for	IN
cord-023443-pvz7dll9	221	18	CD89	CD89	NNP
cord-023443-pvz7dll9	221	19	.	.	.
cord-023443-pvz7dll9	222	1	IgA1	iga1	UH
cord-023443-pvz7dll9	222	2	is	be	VBZ
cord-023443-pvz7dll9	222	3	the	the	DT
cord-023443-pvz7dll9	222	4	vastly	vastly	RB
cord-023443-pvz7dll9	222	5	predominant	predominant	JJ
cord-023443-pvz7dll9	222	6	subclass	subclass	NN
cord-023443-pvz7dll9	222	7	of	of	IN
cord-023443-pvz7dll9	222	8	IgA	IgA	NNP
cord-023443-pvz7dll9	222	9	in	in	IN
cord-023443-pvz7dll9	222	10	the	the	DT
cord-023443-pvz7dll9	222	11	upper	upper	NNP
cord-023443-pvz7dll9	222	12	airways	airway	NNS
cord-023443-pvz7dll9	222	13	and	and	CC
cord-023443-pvz7dll9	222	14	circulation	circulation	NN
cord-023443-pvz7dll9	222	15	of	of	IN
cord-023443-pvz7dll9	222	16	humans	human	NNS
cord-023443-pvz7dll9	222	17	.	.	.
cord-023443-pvz7dll9	223	1	Aims	aim	VBZ
cord-023443-pvz7dll9	223	2	:	:	:
cord-023443-pvz7dll9	224	1	To	to	TO
cord-023443-pvz7dll9	224	2	examine	examine	VB
cord-023443-pvz7dll9	224	3	the	the	DT
cord-023443-pvz7dll9	224	4	effects	effect	NNS
cord-023443-pvz7dll9	224	5	of	of	IN
cord-023443-pvz7dll9	224	6	IgA1	iga1	CD
cord-023443-pvz7dll9	224	7	protease	protease	NN
cord-023443-pvz7dll9	224	8	activity	activity	NN
cord-023443-pvz7dll9	224	9	and	and	CC
cord-023443-pvz7dll9	224	10	complement	complement	VB
cord-023443-pvz7dll9	224	11	on	on	IN
cord-023443-pvz7dll9	224	12	phagocytosis	phagocytosis	NN
cord-023443-pvz7dll9	224	13	of	of	IN
cord-023443-pvz7dll9	224	14	IgA	IgA	NNP
cord-023443-pvz7dll9	224	15	antibody	antibody	NN
cord-023443-pvz7dll9	224	16	-	-	HYPH
cord-023443-pvz7dll9	224	17	coated	coat	VBN
cord-023443-pvz7dll9	224	18	pneumococci	pneumococcus	NNS
cord-023443-pvz7dll9	224	19	by	by	IN
cord-023443-pvz7dll9	224	20	an	an	DT
cord-023443-pvz7dll9	224	21	unstimulated	unstimulated	JJ
cord-023443-pvz7dll9	224	22	human	human	JJ
cord-023443-pvz7dll9	224	23	phagocytic	phagocytic	JJ
cord-023443-pvz7dll9	224	24	cell	cell	NN
cord-023443-pvz7dll9	224	25	line	line	NN
cord-023443-pvz7dll9	224	26	(	(	-LRB-
cord-023443-pvz7dll9	224	27	hl60	hl60	NNP
cord-023443-pvz7dll9	224	28	)	)	-RRB-
cord-023443-pvz7dll9	224	29	.	.	.
cord-023443-pvz7dll9	225	1	Materials	material	NNS
cord-023443-pvz7dll9	225	2	and	and	CC
cord-023443-pvz7dll9	225	3	methods	method	NNS
cord-023443-pvz7dll9	225	4	:	:	:
cord-023443-pvz7dll9	225	5	IgA1	iga1	ADD
cord-023443-pvz7dll9	225	6	and	and	CC
cord-023443-pvz7dll9	225	7	IgA2	IgA2	VBD
cord-023443-pvz7dll9	225	8	monoclonal	monoclonal	JJ
cord-023443-pvz7dll9	225	9	antibodies	antibody	NNS
cord-023443-pvz7dll9	225	10	to	to	IN
cord-023443-pvz7dll9	225	11	serotype	serotype	NN
cord-023443-pvz7dll9	225	12	4	4	CD
cord-023443-pvz7dll9	225	13	pneumococcal	pneumococcal	JJ
cord-023443-pvz7dll9	225	14	capsular	capsular	NN
cord-023443-pvz7dll9	225	15	polysaccharide	polysaccharide	NN
cord-023443-pvz7dll9	225	16	(	(	-LRB-
cord-023443-pvz7dll9	225	17	ps	ps	UH
cord-023443-pvz7dll9	225	18	)	)	-RRB-
cord-023443-pvz7dll9	225	19	were	be	VBD
cord-023443-pvz7dll9	225	20	generated	generate	VBN
cord-023443-pvz7dll9	225	21	by	by	IN
cord-023443-pvz7dll9	225	22	heterohybridoma	heterohybridoma	NN
cord-023443-pvz7dll9	225	23	technique	technique	NN
cord-023443-pvz7dll9	225	24	involving	involve	VBG
cord-023443-pvz7dll9	225	25	B	b	NN
cord-023443-pvz7dll9	225	26	cells	cell	NNS
cord-023443-pvz7dll9	225	27	from	from	IN
cord-023443-pvz7dll9	225	28	human	human	JJ
cord-023443-pvz7dll9	225	29	vaccinees	vaccinee	NNS
cord-023443-pvz7dll9	225	30	.	.	.
cord-023443-pvz7dll9	226	1	Isogenic	Isogenic	NNP
cord-023443-pvz7dll9	226	2	serotype	serotype	NN
cord-023443-pvz7dll9	226	3	4	4	CD
cord-023443-pvz7dll9	226	4	pneumococci	pneumococcus	NNS
cord-023443-pvz7dll9	226	5	with	with	IN
cord-023443-pvz7dll9	226	6	and	and	CC
cord-023443-pvz7dll9	226	7	without	without	IN
cord-023443-pvz7dll9	226	8	IgA1	iga1	PRP$
cord-023443-pvz7dll9	226	9	protease	protease	NN
cord-023443-pvz7dll9	226	10	activity	activity	NN
cord-023443-pvz7dll9	226	11	,	,	,
cord-023443-pvz7dll9	226	12	respectively	respectively	RB
cord-023443-pvz7dll9	226	13	,	,	,
cord-023443-pvz7dll9	226	14	were	be	VBD
cord-023443-pvz7dll9	226	15	obtained	obtain	VBN
cord-023443-pvz7dll9	226	16	after	after	IN
cord-023443-pvz7dll9	226	17	inactivation	inactivation	NN
cord-023443-pvz7dll9	226	18	of	of	IN
cord-023443-pvz7dll9	226	19	the	the	DT
cord-023443-pvz7dll9	226	20	iga	iga	NNP
cord-023443-pvz7dll9	226	21	gene	gene	NN
cord-023443-pvz7dll9	226	22	of	of	IN
cord-023443-pvz7dll9	226	23	the	the	DT
cord-023443-pvz7dll9	226	24	TIGR4	TIGR4	NNP
cord-023443-pvz7dll9	226	25	strain	strain	NN
cord-023443-pvz7dll9	226	26	.	.	.
cord-023443-pvz7dll9	227	1	Opsonophagocytosis	Opsonophagocytosis	NNP
cord-023443-pvz7dll9	227	2	was	be	VBD
cord-023443-pvz7dll9	227	3	quantitated	quantitate	VBN
cord-023443-pvz7dll9	227	4	using	use	VBG
cord-023443-pvz7dll9	227	5	the	the	DT
cord-023443-pvz7dll9	227	6	assay	assay	NN
cord-023443-pvz7dll9	227	7	described	describe	VBN
cord-023443-pvz7dll9	227	8	by	by	IN
cord-023443-pvz7dll9	227	9	Romero	Romero	NNP
cord-023443-pvz7dll9	227	10	-	-	HYPH
cord-023443-pvz7dll9	227	11	Steiner	Steiner	NNP
cord-023443-pvz7dll9	227	12	et	et	NNP
cord-023443-pvz7dll9	227	13	al	al	NNP
cord-023443-pvz7dll9	227	14	.	.	.
cord-023443-pvz7dll9	228	1	Based	base	VBN
cord-023443-pvz7dll9	228	2	on	on	IN
cord-023443-pvz7dll9	228	3	enumeration	enumeration	NN
cord-023443-pvz7dll9	228	4	of	of	IN
cord-023443-pvz7dll9	228	5	surviving	survive	VBG
cord-023443-pvz7dll9	228	6	bacteria	bacteria	NNS
cord-023443-pvz7dll9	228	7	by	by	IN
cord-023443-pvz7dll9	228	8	culture	culture	NN
cord-023443-pvz7dll9	228	9	.	.	.
cord-023443-pvz7dll9	229	1	The	the	DT
cord-023443-pvz7dll9	229	2	integrity	integrity	NN
cord-023443-pvz7dll9	229	3	of	of	IN
cord-023443-pvz7dll9	229	4	IgA	IgA	NNP
cord-023443-pvz7dll9	229	5	molecules	molecule	NNS
cord-023443-pvz7dll9	229	6	was	be	VBD
cord-023443-pvz7dll9	229	7	examined	examine	VBN
cord-023443-pvz7dll9	229	8	by	by	IN
cord-023443-pvz7dll9	229	9	western	western	JJ
cord-023443-pvz7dll9	229	10	blotting	blotting	NN
cord-023443-pvz7dll9	229	11	.	.	.
cord-023443-pvz7dll9	230	1	Results	result	NNS
cord-023443-pvz7dll9	230	2	:	:	:
cord-023443-pvz7dll9	231	1	Both	both	CC
cord-023443-pvz7dll9	231	2	IgA1	iga1	PRP
cord-023443-pvz7dll9	231	3	and	and	CC
cord-023443-pvz7dll9	231	4	IgA2	IgA2	VBD
cord-023443-pvz7dll9	231	5	antibody	antibody	NN
cord-023443-pvz7dll9	231	6	to	to	IN
cord-023443-pvz7dll9	231	7	type-4	type-4	NNP
cord-023443-pvz7dll9	231	8	polysaccharide	polysaccharide	NN
cord-023443-pvz7dll9	231	9	-	-	HYPH
cord-023443-pvz7dll9	231	10	induced	induce	VBN
cord-023443-pvz7dll9	231	11	phagocytosis	phagocytosis	NN
cord-023443-pvz7dll9	231	12	of	of	IN
cord-023443-pvz7dll9	231	13	IgA1	iga1	DT
cord-023443-pvz7dll9	231	14	protease	protease	NN
cord-023443-pvz7dll9	231	15	-	-	HYPH
cord-023443-pvz7dll9	231	16	deficient	deficient	JJ
cord-023443-pvz7dll9	232	1	type-4	type-4	NNP
cord-023443-pvz7dll9	232	2	pneumococci	pneumococcus	NNS
cord-023443-pvz7dll9	232	3	equally	equally	RB
cord-023443-pvz7dll9	232	4	well	well	RB
cord-023443-pvz7dll9	232	5	in	in	IN
cord-023443-pvz7dll9	232	6	the	the	DT
cord-023443-pvz7dll9	232	7	absence	absence	NN
cord-023443-pvz7dll9	232	8	as	as	IN
cord-023443-pvz7dll9	232	9	in	in	IN
cord-023443-pvz7dll9	232	10	the	the	DT
cord-023443-pvz7dll9	232	11	presence	presence	NN
cord-023443-pvz7dll9	232	12	of	of	IN
cord-023443-pvz7dll9	232	13	complement	complement	NN
cord-023443-pvz7dll9	232	14	.	.	.
cord-023443-pvz7dll9	233	1	Iga1	iga1	JJ
cord-023443-pvz7dll9	233	2	antibody	antibody	NN
cord-023443-pvz7dll9	233	3	to	to	IN
cord-023443-pvz7dll9	233	4	type-4	type-4	NNP
cord-023443-pvz7dll9	233	5	polysaccharide	polysaccharide	NN
cord-023443-pvz7dll9	233	6	displayed	display	VBD
cord-023443-pvz7dll9	233	7	a	a	DT
cord-023443-pvz7dll9	233	8	fourfold	fourfold	JJ
cord-023443-pvz7dll9	233	9	higher	high	JJR
cord-023443-pvz7dll9	233	10	opsonophagocytosis	opsonophagocytosis	NN
cord-023443-pvz7dll9	233	11	titer	titer	NN
cord-023443-pvz7dll9	233	12	against	against	IN
cord-023443-pvz7dll9	233	13	IgA1	iga1	XX
cord-023443-pvz7dll9	233	14	protease	protease	NN
cord-023443-pvz7dll9	233	15	deficient	deficient	JJ
cord-023443-pvz7dll9	233	16	compared	compare	VBN
cord-023443-pvz7dll9	233	17	to	to	IN
cord-023443-pvz7dll9	233	18	homologous	homologous	JJ
cord-023443-pvz7dll9	233	19	wildtype	wildtype	NN
cord-023443-pvz7dll9	233	20	target	target	NN
cord-023443-pvz7dll9	233	21	bacteria	bacteria	NNS
cord-023443-pvz7dll9	233	22	.	.	.
cord-023443-pvz7dll9	234	1	A	a	DT
cord-023443-pvz7dll9	234	2	similar	similar	JJ
cord-023443-pvz7dll9	234	3	effect	effect	NN
cord-023443-pvz7dll9	234	4	of	of	IN
cord-023443-pvz7dll9	234	5	IgA1	iga1	CD
cord-023443-pvz7dll9	234	6	protease	protease	NN
cord-023443-pvz7dll9	234	7	activity	activity	NN
cord-023443-pvz7dll9	234	8	of	of	IN
cord-023443-pvz7dll9	234	9	the	the	DT
cord-023443-pvz7dll9	234	10	target	target	NN
cord-023443-pvz7dll9	234	11	bacteria	bacteria	NNS
cord-023443-pvz7dll9	234	12	was	be	VBD
cord-023443-pvz7dll9	234	13	not	not	RB
cord-023443-pvz7dll9	234	14	observed	observe	VBN
cord-023443-pvz7dll9	234	15	in	in	IN
cord-023443-pvz7dll9	234	16	a	a	DT
cord-023443-pvz7dll9	234	17	parallel	parallel	JJ
cord-023443-pvz7dll9	234	18	experiment	experiment	NN
cord-023443-pvz7dll9	234	19	where	where	WRB
cord-023443-pvz7dll9	234	20	IgA2	iga2	JJ
cord-023443-pvz7dll9	234	21	antibody	antibody	NN
cord-023443-pvz7dll9	234	22	to	to	IN
cord-023443-pvz7dll9	234	23	type-4	type-4	NNP
cord-023443-pvz7dll9	234	24	polysaccharide	polysaccharide	NN
cord-023443-pvz7dll9	234	25	served	serve	VBD
cord-023443-pvz7dll9	234	26	as	as	IN
cord-023443-pvz7dll9	234	27	opsonin	opsonin	NNP
cord-023443-pvz7dll9	234	28	.	.	.
cord-023443-pvz7dll9	235	1	IgA1	iga1	DT
cord-023443-pvz7dll9	235	2	antibody	antibody	NN
cord-023443-pvz7dll9	235	3	extracted	extract	VBD
cord-023443-pvz7dll9	235	4	from	from	IN
cord-023443-pvz7dll9	235	5	IgA1	iga1	DT
cord-023443-pvz7dll9	235	6	protease	protease	NN
cord-023443-pvz7dll9	235	7	-	-	HYPH
cord-023443-pvz7dll9	235	8	producing	produce	VBG
cord-023443-pvz7dll9	235	9	target	target	NN
cord-023443-pvz7dll9	235	10	bacteria	bacteria	NNS
cord-023443-pvz7dll9	235	11	was	be	VBD
cord-023443-pvz7dll9	235	12	almost	almost	RB
cord-023443-pvz7dll9	235	13	exclusively	exclusively	RB
cord-023443-pvz7dll9	235	14	in	in	IN
cord-023443-pvz7dll9	235	15	the	the	DT
cord-023443-pvz7dll9	235	16	form	form	NN
cord-023443-pvz7dll9	235	17	of	of	IN
cord-023443-pvz7dll9	235	18	Faba	Faba	NNP
cord-023443-pvz7dll9	235	19	.	.	.
cord-023443-pvz7dll9	236	1	Conversely	conversely	RB
cord-023443-pvz7dll9	236	2	,	,	,
cord-023443-pvz7dll9	236	3	IgA1	iga1	RB
cord-023443-pvz7dll9	236	4	from	from	IN
cord-023443-pvz7dll9	236	5	protease	protease	NN
cord-023443-pvz7dll9	236	6	-	-	HYPH
cord-023443-pvz7dll9	236	7	deficient	deficient	JJ
cord-023443-pvz7dll9	236	8	bacteria	bacteria	NNS
cord-023443-pvz7dll9	236	9	and	and	CC
cord-023443-pvz7dll9	236	10	IgA2	iga2	NN
cord-023443-pvz7dll9	236	11	from	from	IN
cord-023443-pvz7dll9	236	12	both	both	DT
cord-023443-pvz7dll9	236	13	types	type	NNS
cord-023443-pvz7dll9	236	14	of	of	IN
cord-023443-pvz7dll9	236	15	bacteria	bacteria	NNS
cord-023443-pvz7dll9	236	16	were	be	VBD
cord-023443-pvz7dll9	236	17	intact	intact	JJ
cord-023443-pvz7dll9	236	18	.	.	.
cord-023443-pvz7dll9	237	1	Conclusions	conclusion	NNS
cord-023443-pvz7dll9	237	2	:	:	:
cord-023443-pvz7dll9	238	1	These	these	DT
cord-023443-pvz7dll9	238	2	results	result	NNS
cord-023443-pvz7dll9	238	3	indicate	indicate	VBP
cord-023443-pvz7dll9	238	4	that	that	IN
cord-023443-pvz7dll9	238	5	the	the	DT
cord-023443-pvz7dll9	238	6	IgA1	iga1	CD
cord-023443-pvz7dll9	238	7	protease	protease	NN
cord-023443-pvz7dll9	238	8	activity	activity	NN
cord-023443-pvz7dll9	238	9	of	of	IN
cord-023443-pvz7dll9	238	10	S.	S.	NNP
cord-023443-pvz7dll9	238	11	neumoniae	neumoniae	NNS
cord-023443-pvz7dll9	238	12	may	may	MD
cord-023443-pvz7dll9	238	13	help	help	VB
cord-023443-pvz7dll9	238	14	the	the	DT
cord-023443-pvz7dll9	238	15	bacteria	bacteria	NNS
cord-023443-pvz7dll9	238	16	escape	escape	VB
cord-023443-pvz7dll9	238	17	IgA1	iga1	ADD
cord-023443-pvz7dll9	238	18	antibody	antibody	NN
cord-023443-pvz7dll9	238	19	-	-	HYPH
cord-023443-pvz7dll9	238	20	mediated	mediate	VBN
cord-023443-pvz7dll9	238	21	opsonophagocytosis	opsonophagocytosis	NN
cord-023443-pvz7dll9	238	22	.	.	.
cord-023443-pvz7dll9	239	1	Besides	besides	RB
cord-023443-pvz7dll9	239	2	,	,	,
cord-023443-pvz7dll9	239	3	in	in	IN
cord-023443-pvz7dll9	239	4	these	these	DT
cord-023443-pvz7dll9	239	5	experiments	experiment	NNS
cord-023443-pvz7dll9	239	6	,	,	,
cord-023443-pvz7dll9	239	7	IgA	IgA	NNP
cord-023443-pvz7dll9	239	8	-	-	HYPH
cord-023443-pvz7dll9	239	9	mediated	mediate	VBN
cord-023443-pvz7dll9	239	10	opsonophagocytosis	opsonophagocytosis	NN
cord-023443-pvz7dll9	239	11	was	be	VBD
cord-023443-pvz7dll9	239	12	independent	independent	JJ
cord-023443-pvz7dll9	239	13	of	of	IN
cord-023443-pvz7dll9	239	14	complement	complement	NN
cord-023443-pvz7dll9	239	15	.	.	.
cord-023443-pvz7dll9	240	1	Vitamins	vitamin	NNS
cord-023443-pvz7dll9	240	2	E	e	NN
cord-023443-pvz7dll9	240	3	and	and	CC
cord-023443-pvz7dll9	240	4	C	C	NNP
cord-023443-pvz7dll9	240	5	have	have	VBP
cord-023443-pvz7dll9	240	6	been	be	VBN
cord-023443-pvz7dll9	240	7	found	find	VBN
cord-023443-pvz7dll9	240	8	to	to	TO
cord-023443-pvz7dll9	240	9	increase	increase	VB
cord-023443-pvz7dll9	240	10	the	the	DT
cord-023443-pvz7dll9	240	11	cellular	cellular	JJ
cord-023443-pvz7dll9	240	12	and	and	CC
cord-023443-pvz7dll9	240	13	humeral	humeral	JJ
cord-023443-pvz7dll9	240	14	immunity	immunity	NN
cord-023443-pvz7dll9	240	15	of	of	IN
cord-023443-pvz7dll9	240	16	pigs	pig	NNS
cord-023443-pvz7dll9	240	17	.	.	.
cord-023443-pvz7dll9	241	1	Vitamin	vitamin	NN
cord-023443-pvz7dll9	241	2	E	e	NN
cord-023443-pvz7dll9	241	3	deficiency	deficiency	NN
cord-023443-pvz7dll9	241	4	has	have	VBZ
cord-023443-pvz7dll9	241	5	also	also	RB
cord-023443-pvz7dll9	241	6	been	be	VBN
cord-023443-pvz7dll9	241	7	found	find	VBN
cord-023443-pvz7dll9	241	8	to	to	TO
cord-023443-pvz7dll9	241	9	predispose	predispose	VB
cord-023443-pvz7dll9	241	10	pigs	pig	NNS
cord-023443-pvz7dll9	241	11	to	to	IN
cord-023443-pvz7dll9	241	12	different	different	JJ
cord-023443-pvz7dll9	241	13	diseases	disease	NNS
cord-023443-pvz7dll9	241	14	,	,	,
cord-023443-pvz7dll9	241	15	E.	E.	NNP
cord-023443-pvz7dll9	241	16	coli	coli	VBZ
cord-023443-pvz7dll9	241	17	infection	infection	NN
cord-023443-pvz7dll9	241	18	is	be	VBZ
cord-023443-pvz7dll9	241	19	one	one	CD
cord-023443-pvz7dll9	241	20	among	among	IN
cord-023443-pvz7dll9	241	21	them	-PRON-	PRP
cord-023443-pvz7dll9	241	22	.	.	.
cord-023443-pvz7dll9	242	1	After	after	IN
cord-023443-pvz7dll9	242	2	weaning	wean	VBG
cord-023443-pvz7dll9	242	3	,	,	,
cord-023443-pvz7dll9	242	4	the	the	DT
cord-023443-pvz7dll9	242	5	vitamin	vitamin	NN
cord-023443-pvz7dll9	242	6	E	e	NN
cord-023443-pvz7dll9	242	7	status	status	NN
cord-023443-pvz7dll9	242	8	of	of	IN
cord-023443-pvz7dll9	242	9	pigs	pig	NNS
cord-023443-pvz7dll9	242	10	often	often	RB
cord-023443-pvz7dll9	242	11	decreases	decrease	VBZ
cord-023443-pvz7dll9	242	12	to	to	IN
cord-023443-pvz7dll9	242	13	a	a	DT
cord-023443-pvz7dll9	242	14	critical	critical	JJ
cord-023443-pvz7dll9	242	15	low	low	JJ
cord-023443-pvz7dll9	242	16	level	level	NN
cord-023443-pvz7dll9	242	17	.	.	.
cord-023443-pvz7dll9	243	1	In	in	IN
cord-023443-pvz7dll9	243	2	this	this	DT
cord-023443-pvz7dll9	243	3	experiment	experiment	NN
cord-023443-pvz7dll9	243	4	,	,	,
cord-023443-pvz7dll9	243	5	we	-PRON-	PRP
cord-023443-pvz7dll9	243	6	studied	study	VBD
cord-023443-pvz7dll9	243	7	whether	whether	IN
cord-023443-pvz7dll9	243	8	vitamin	vitamin	NN
cord-023443-pvz7dll9	243	9	C	c	NN
cord-023443-pvz7dll9	243	10	supplementation	supplementation	NN
cord-023443-pvz7dll9	243	11	would	would	MD
cord-023443-pvz7dll9	243	12	be	be	VB
cord-023443-pvz7dll9	243	13	a	a	DT
cord-023443-pvz7dll9	243	14	possible	possible	JJ
cord-023443-pvz7dll9	243	15	feeding	feeding	NN
cord-023443-pvz7dll9	243	16	strategy	strategy	NN
cord-023443-pvz7dll9	243	17	to	to	TO
cord-023443-pvz7dll9	243	18	optimize	optimize	VB
cord-023443-pvz7dll9	243	19	the	the	DT
cord-023443-pvz7dll9	243	20	immune	immune	JJ
cord-023443-pvz7dll9	243	21	status	status	NN
cord-023443-pvz7dll9	243	22	of	of	IN
cord-023443-pvz7dll9	243	23	weaners	weaner	NNS
cord-023443-pvz7dll9	243	24	.	.	.
cord-023443-pvz7dll9	244	1	The	the	DT
cord-023443-pvz7dll9	244	2	interaction	interaction	NN
cord-023443-pvz7dll9	244	3	between	between	IN
cord-023443-pvz7dll9	244	4	vitamin	vitamin	NN
cord-023443-pvz7dll9	244	5	E	e	NN
cord-023443-pvz7dll9	244	6	and	and	CC
cord-023443-pvz7dll9	244	7	C	C	NNP
cord-023443-pvz7dll9	244	8	is	be	VBZ
cord-023443-pvz7dll9	244	9	interesting	interesting	JJ
cord-023443-pvz7dll9	244	10	due	due	IN
cord-023443-pvz7dll9	244	11	to	to	IN
cord-023443-pvz7dll9	244	12	the	the	DT
cord-023443-pvz7dll9	244	13	reported	report	VBN
cord-023443-pvz7dll9	244	14	sparing	spare	VBG
cord-023443-pvz7dll9	244	15	action	action	NN
cord-023443-pvz7dll9	244	16	on	on	IN
cord-023443-pvz7dll9	244	17	vitamin	vitamin	NN
cord-023443-pvz7dll9	244	18	E	e	NN
cord-023443-pvz7dll9	244	19	or	or	CC
cord-023443-pvz7dll9	244	20	synergism	synergism	NN
cord-023443-pvz7dll9	244	21	between	between	IN
cord-023443-pvz7dll9	244	22	these	these	DT
cord-023443-pvz7dll9	244	23	to	to	IN
cord-023443-pvz7dll9	244	24	vitamins	vitamin	NNS
cord-023443-pvz7dll9	244	25	.	.	.
cord-023443-pvz7dll9	245	1	Piglets	piglet	NNS
cord-023443-pvz7dll9	245	2	were	be	VBD
cord-023443-pvz7dll9	245	3	weaned	wean	VBN
cord-023443-pvz7dll9	245	4	at	at	IN
cord-023443-pvz7dll9	245	5	day	day	NN
cord-023443-pvz7dll9	245	6	28	28	CD
cord-023443-pvz7dll9	245	7	of	of	IN
cord-023443-pvz7dll9	245	8	age	age	NN
cord-023443-pvz7dll9	245	9	from	from	IN
cord-023443-pvz7dll9	245	10	sows	sow	NNS
cord-023443-pvz7dll9	245	11	fed	feed	VBD
cord-023443-pvz7dll9	245	12	increasing	increase	VBG
cord-023443-pvz7dll9	245	13	dietary	dietary	JJ
cord-023443-pvz7dll9	245	14	vitamin	vitamin	NN
cord-023443-pvz7dll9	245	15	E	e	NN
cord-023443-pvz7dll9	245	16	during	during	IN
cord-023443-pvz7dll9	245	17	lactation	lactation	NN
cord-023443-pvz7dll9	245	18	,	,	,
cord-023443-pvz7dll9	245	19	and	and	CC
cord-023443-pvz7dll9	245	20	piglets	piglet	NNS
cord-023443-pvz7dll9	245	21	were	be	VBD
cord-023443-pvz7dll9	245	22	during	during	IN
cord-023443-pvz7dll9	245	23	the	the	DT
cord-023443-pvz7dll9	245	24	following	following	JJ
cord-023443-pvz7dll9	245	25	3	3	CD
cord-023443-pvz7dll9	245	26	weeks	week	NNS
cord-023443-pvz7dll9	245	27	fed	feed	VBN
cord-023443-pvz7dll9	245	28	either	either	CC
cord-023443-pvz7dll9	245	29	a	a	DT
cord-023443-pvz7dll9	245	30	control	control	NN
cord-023443-pvz7dll9	245	31	diet	diet	NN
cord-023443-pvz7dll9	245	32	or	or	CC
cord-023443-pvz7dll9	245	33	this	this	DT
cord-023443-pvz7dll9	245	34	diet	diet	NN
cord-023443-pvz7dll9	245	35	supplemented	supplement	VBD
cord-023443-pvz7dll9	245	36	with	with	IN
cord-023443-pvz7dll9	245	37	500	500	CD
cord-023443-pvz7dll9	245	38	mg	mg	NNP
cord-023443-pvz7dll9	245	39	STAY	stay	NN
cord-023443-pvz7dll9	245	40	-	-	HYPH
cord-023443-pvz7dll9	245	41	C	C	NNP
cord-023443-pvz7dll9	245	42	per	per	IN
cord-023443-pvz7dll9	245	43	kg	kg	NN
cord-023443-pvz7dll9	245	44	.	.	.
cord-023443-pvz7dll9	246	1	Blood	blood	NN
cord-023443-pvz7dll9	246	2	sampling	sampling	NN
cord-023443-pvz7dll9	246	3	was	be	VBD
cord-023443-pvz7dll9	246	4	obtained	obtain	VBN
cord-023443-pvz7dll9	246	5	weekly	weekly	RB
cord-023443-pvz7dll9	246	6	from	from	IN
cord-023443-pvz7dll9	246	7	day	day	NN
cord-023443-pvz7dll9	246	8	28	28	CD
cord-023443-pvz7dll9	246	9	and	and	CC
cord-023443-pvz7dll9	246	10	until	until	IN
cord-023443-pvz7dll9	246	11	day	day	NN
cord-023443-pvz7dll9	246	12	49	49	CD
cord-023443-pvz7dll9	246	13	of	of	IN
cord-023443-pvz7dll9	246	14	age	age	NN
cord-023443-pvz7dll9	246	15	.	.	.
cord-023443-pvz7dll9	247	1	On	on	IN
cord-023443-pvz7dll9	247	2	the	the	DT
cord-023443-pvz7dll9	247	3	same	same	JJ
cord-023443-pvz7dll9	247	4	days	day	NNS
cord-023443-pvz7dll9	247	5	,	,	,
cord-023443-pvz7dll9	247	6	one	one	CD
cord-023443-pvz7dll9	247	7	piglet	piglet	NN
cord-023443-pvz7dll9	247	8	per	per	IN
cord-023443-pvz7dll9	247	9	dietary	dietary	JJ
cord-023443-pvz7dll9	247	10	treatment	treatment	NN
cord-023443-pvz7dll9	247	11	was	be	VBD
cord-023443-pvz7dll9	247	12	killed	kill	VBN
cord-023443-pvz7dll9	247	13	and	and	CC
cord-023443-pvz7dll9	247	14	alveolar	alveolar	NN
cord-023443-pvz7dll9	247	15	macrophages	macrophage	NNS
cord-023443-pvz7dll9	247	16	(	(	-LRB-
cord-023443-pvz7dll9	247	17	AM	am	NN
cord-023443-pvz7dll9	247	18	)	)	-RRB-
cord-023443-pvz7dll9	247	19	were	be	VBD
cord-023443-pvz7dll9	247	20	harvested	harvest	VBN
cord-023443-pvz7dll9	247	21	.	.	.
cord-023443-pvz7dll9	248	1	Vitamin	vitamin	NN
cord-023443-pvz7dll9	248	2	C	c	NN
cord-023443-pvz7dll9	248	3	supplementation	supplementation	NN
cord-023443-pvz7dll9	248	4	increased	increase	VBD
cord-023443-pvz7dll9	248	5	the	the	DT
cord-023443-pvz7dll9	248	6	concentration	concentration	NN
cord-023443-pvz7dll9	248	7	of	of	IN
cord-023443-pvz7dll9	248	8	IgM	IgM	NNP
cord-023443-pvz7dll9	248	9	in	in	IN
cord-023443-pvz7dll9	248	10	serum	serum	NN
cord-023443-pvz7dll9	248	11	of	of	IN
cord-023443-pvz7dll9	248	12	piglets	piglet	NNS
cord-023443-pvz7dll9	248	13	throughout	throughout	IN
cord-023443-pvz7dll9	248	14	the	the	DT
cord-023443-pvz7dll9	248	15	weaning	weaning	NN
cord-023443-pvz7dll9	248	16	period	period	NN
cord-023443-pvz7dll9	248	17	.	.	.
cord-023443-pvz7dll9	249	1	Although	although	IN
cord-023443-pvz7dll9	249	2	the	the	DT
cord-023443-pvz7dll9	249	3	vitamin	vitamin	NN
cord-023443-pvz7dll9	249	4	E	e	NN
cord-023443-pvz7dll9	249	5	concentration	concentration	NN
cord-023443-pvz7dll9	249	6	in	in	IN
cord-023443-pvz7dll9	249	7	AM	AM	NNP
cord-023443-pvz7dll9	249	8	decreased	decrease	VBD
cord-023443-pvz7dll9	249	9	with	with	IN
cord-023443-pvz7dll9	249	10	increasing	increase	VBG
cord-023443-pvz7dll9	249	11	age	age	NN
cord-023443-pvz7dll9	249	12	of	of	IN
cord-023443-pvz7dll9	249	13	the	the	DT
cord-023443-pvz7dll9	249	14	piglets	piglet	NNS
cord-023443-pvz7dll9	249	15	,	,	,
cord-023443-pvz7dll9	249	16	the	the	DT
cord-023443-pvz7dll9	249	17	concentration	concentration	NN
cord-023443-pvz7dll9	249	18	was	be	VBD
cord-023443-pvz7dll9	249	19	numerically	numerically	RB
cord-023443-pvz7dll9	249	20	higher	high	JJR
cord-023443-pvz7dll9	249	21	in	in	IN
cord-023443-pvz7dll9	249	22	piglets	piglet	NNS
cord-023443-pvz7dll9	249	23	of	of	IN
cord-023443-pvz7dll9	249	24	sows	sow	NNS
cord-023443-pvz7dll9	249	25	fed	feed	VBD
cord-023443-pvz7dll9	249	26	the	the	DT
cord-023443-pvz7dll9	249	27	high	high	JJ
cord-023443-pvz7dll9	249	28	dietary	dietary	JJ
cord-023443-pvz7dll9	249	29	level	level	NN
cord-023443-pvz7dll9	249	30	of	of	IN
cord-023443-pvz7dll9	249	31	vitamin	vitamin	NN
cord-023443-pvz7dll9	249	32	E.	E.	NNP
cord-023443-pvz7dll9	250	1	However	however	RB
cord-023443-pvz7dll9	250	2	,	,	,
cord-023443-pvz7dll9	250	3	vitamin	vitamin	NN
cord-023443-pvz7dll9	250	4	C	c	NN
cord-023443-pvz7dll9	250	5	supplementation	supplementation	NN
cord-023443-pvz7dll9	250	6	tended	tend	VBD
cord-023443-pvz7dll9	250	7	to	to	TO
cord-023443-pvz7dll9	250	8	increase	increase	VB
cord-023443-pvz7dll9	250	9	the	the	DT
cord-023443-pvz7dll9	250	10	total	total	JJ
cord-023443-pvz7dll9	250	11	AM	AM	NNP
cord-023443-pvz7dll9	250	12	concentration	concentration	NN
cord-023443-pvz7dll9	250	13	of	of	IN
cord-023443-pvz7dll9	250	14	vitamin	vitamin	NN
cord-023443-pvz7dll9	250	15	E	e	NN
cord-023443-pvz7dll9	250	16	after	after	IN
cord-023443-pvz7dll9	250	17	weaning	weaning	NN
cord-023443-pvz7dll9	250	18	and	and	CC
cord-023443-pvz7dll9	250	19	increased	increase	VBD
cord-023443-pvz7dll9	250	20	the	the	DT
cord-023443-pvz7dll9	250	21	proportion	proportion	NN
cord-023443-pvz7dll9	250	22	of	of	IN
cord-023443-pvz7dll9	250	23	the	the	DT
cord-023443-pvz7dll9	250	24	biologically	biologically	RB
cord-023443-pvz7dll9	250	25	most	most	RBS
cord-023443-pvz7dll9	250	26	active	active	JJ
cord-023443-pvz7dll9	250	27	isomer	isomer	NN
cord-023443-pvz7dll9	250	28	of	of	IN
cord-023443-pvz7dll9	250	29	vitamin	vitamin	NN
cord-023443-pvz7dll9	250	30	E	e	NN
cord-023443-pvz7dll9	250	31	[	[	-LRB-
cord-023443-pvz7dll9	250	32	RRR-(a	rrr-(a	NN
cord-023443-pvz7dll9	250	33	-	-	HYPH
cord-023443-pvz7dll9	250	34	tocopherol	tocopherol	NN
cord-023443-pvz7dll9	250	35	)	)	-RRB-
cord-023443-pvz7dll9	250	36	]	]	-RRB-
cord-023443-pvz7dll9	250	37	in	in	IN
cord-023443-pvz7dll9	250	38	the	the	DT
cord-023443-pvz7dll9	250	39	AM	am	NN
cord-023443-pvz7dll9	250	40	.	.	.
cord-023443-pvz7dll9	251	1	The	the	DT
cord-023443-pvz7dll9	251	2	eicosanoid	eicosanoid	JJ
cord-023443-pvz7dll9	251	3	synthesis	synthesis	NN
cord-023443-pvz7dll9	251	4	by	by	IN
cord-023443-pvz7dll9	251	5	AM	AM	NNP
cord-023443-pvz7dll9	251	6	was	be	VBD
cord-023443-pvz7dll9	251	7	not	not	RB
cord-023443-pvz7dll9	251	8	influenced	influence	VBN
cord-023443-pvz7dll9	251	9	by	by	IN
cord-023443-pvz7dll9	251	10	the	the	DT
cord-023443-pvz7dll9	251	11	vitamin	vitamin	NN
cord-023443-pvz7dll9	251	12	C	C	NNP
cord-023443-pvz7dll9	251	13	supplementation	supplementation	NN
cord-023443-pvz7dll9	251	14	,	,	,
cord-023443-pvz7dll9	251	15	but	but	CC
cord-023443-pvz7dll9	251	16	the	the	DT
cord-023443-pvz7dll9	251	17	synthesis	synthesis	NN
cord-023443-pvz7dll9	251	18	of	of	IN
cord-023443-pvz7dll9	251	19	leukotriene	leukotriene	NN
cord-023443-pvz7dll9	251	20	B4	B4	NNP
cord-023443-pvz7dll9	251	21	was	be	VBD
cord-023443-pvz7dll9	251	22	decreased	decrease	VBN
cord-023443-pvz7dll9	251	23	2	2	CD
cord-023443-pvz7dll9	251	24	weeks	week	NNS
cord-023443-pvz7dll9	251	25	after	after	IN
cord-023443-pvz7dll9	251	26	weaning	wean	VBG
cord-023443-pvz7dll9	251	27	compared	compare	VBN
cord-023443-pvz7dll9	251	28	to	to	IN
cord-023443-pvz7dll9	251	29	other	other	JJ
cord-023443-pvz7dll9	251	30	days	day	NNS
cord-023443-pvz7dll9	251	31	of	of	IN
cord-023443-pvz7dll9	251	32	AM	AM	NNP
cord-023443-pvz7dll9	251	33	harvesting	harvest	VBG
cord-023443-pvz7dll9	251	34	.	.	.
cord-023443-pvz7dll9	252	1	In	in	IN
cord-023443-pvz7dll9	252	2	conclusion	conclusion	NN
cord-023443-pvz7dll9	252	3	,	,	,
cord-023443-pvz7dll9	252	4	dietary	dietary	JJ
cord-023443-pvz7dll9	252	5	vitamin	vitamin	NN
cord-023443-pvz7dll9	252	6	C	C	NNP
cord-023443-pvz7dll9	252	7	supplementation	supplementation	NN
cord-023443-pvz7dll9	252	8	improved	improve	VBD
cord-023443-pvz7dll9	252	9	the	the	DT
cord-023443-pvz7dll9	252	10	immune	immune	JJ
cord-023443-pvz7dll9	252	11	responses	response	NNS
cord-023443-pvz7dll9	252	12	of	of	IN
cord-023443-pvz7dll9	252	13	piglets	piglet	NNS
cord-023443-pvz7dll9	252	14	after	after	IN
cord-023443-pvz7dll9	252	15	weaning	wean	VBG
cord-023443-pvz7dll9	252	16	.	.	.
cord-023443-pvz7dll9	253	1	A	a	DT
cord-023443-pvz7dll9	253	2	whole	whole	JJ
cord-023443-pvz7dll9	253	3	blood	blood	NN
cord-023443-pvz7dll9	253	4	stimulation	stimulation	NN
cord-023443-pvz7dll9	253	5	assay	assay	NN
cord-023443-pvz7dll9	253	6	with	with	IN
cord-023443-pvz7dll9	253	7	Escherichia	Escherichia	NNP
cord-023443-pvz7dll9	253	8	coli	coli	NNS
cord-023443-pvz7dll9	253	9	(	(	-LRB-
cord-023443-pvz7dll9	253	10	O111	O111	NNS
cord-023443-pvz7dll9	253	11	:	:	:
cord-023443-pvz7dll9	253	12	B4	B4	NNP
cord-023443-pvz7dll9	253	13	)	)	-RRB-
cord-023443-pvz7dll9	253	14	endotoxin	endotoxin	NN
cord-023443-pvz7dll9	253	15	was	be	VBD
cord-023443-pvz7dll9	253	16	established	establish	VBN
cord-023443-pvz7dll9	253	17	to	to	TO
cord-023443-pvz7dll9	253	18	measure	measure	VB
cord-023443-pvz7dll9	253	19	the	the	DT
cord-023443-pvz7dll9	253	20	capacity	capacity	NN
cord-023443-pvz7dll9	253	21	of	of	IN
cord-023443-pvz7dll9	253	22	dairy	dairy	NN
cord-023443-pvz7dll9	253	23	cows	cow	NNS
cord-023443-pvz7dll9	253	24	to	to	TO
cord-023443-pvz7dll9	253	25	produce	produce	VB
cord-023443-pvz7dll9	253	26	the	the	DT
cord-023443-pvz7dll9	253	27	proinflammatory	proinflammatory	JJ
cord-023443-pvz7dll9	253	28	cytokine	cytokine	NN
cord-023443-pvz7dll9	253	29	tumour	tumour	NN
cord-023443-pvz7dll9	253	30	necrosis	necrosis	NN
cord-023443-pvz7dll9	253	31	factor	factor	NN
cord-023443-pvz7dll9	253	32	-	-	:
cord-023443-pvz7dll9	253	33	a	a	DT
cord-023443-pvz7dll9	253	34	(	(	-LRB-
cord-023443-pvz7dll9	253	35	TNF	TNF	NNP
cord-023443-pvz7dll9	253	36	-	-	HYPH
cord-023443-pvz7dll9	253	37	a	a	LS
cord-023443-pvz7dll9	253	38	)	)	-RRB-
cord-023443-pvz7dll9	253	39	ex	ex	FW
cord-023443-pvz7dll9	253	40	vivo	vivo	NN
cord-023443-pvz7dll9	253	41	.	.	.
cord-023443-pvz7dll9	254	1	Initially	initially	RB
cord-023443-pvz7dll9	254	2	,	,	,
cord-023443-pvz7dll9	254	3	a	a	DT
cord-023443-pvz7dll9	254	4	time	time	NN
cord-023443-pvz7dll9	254	5	-	-	HYPH
cord-023443-pvz7dll9	254	6	and	and	CC
cord-023443-pvz7dll9	254	7	dose	dose	NN
cord-023443-pvz7dll9	254	8	-	-	HYPH
cord-023443-pvz7dll9	254	9	dependent	dependent	JJ
cord-023443-pvz7dll9	254	10	study	study	NN
cord-023443-pvz7dll9	254	11	was	be	VBD
cord-023443-pvz7dll9	254	12	carried	carry	VBN
cord-023443-pvz7dll9	254	13	out	out	RP
cord-023443-pvz7dll9	254	14	to	to	TO
cord-023443-pvz7dll9	254	15	find	find	VB
cord-023443-pvz7dll9	254	16	the	the	DT
cord-023443-pvz7dll9	254	17	optimal	optimal	JJ
cord-023443-pvz7dll9	254	18	stimulation	stimulation	NN
cord-023443-pvz7dll9	254	19	conditions	condition	NNS
cord-023443-pvz7dll9	254	20	for	for	IN
cord-023443-pvz7dll9	254	21	the	the	DT
cord-023443-pvz7dll9	254	22	TNF	TNF	NNP
cord-023443-pvz7dll9	254	23	-	-	:
cord-023443-pvz7dll9	254	24	a	a	DT
cord-023443-pvz7dll9	254	25	response	response	NN
cord-023443-pvz7dll9	254	26	.	.	.
cord-023443-pvz7dll9	255	1	The	the	DT
cord-023443-pvz7dll9	255	2	TNF	TNF	NNP
cord-023443-pvz7dll9	255	3	-	-	:
cord-023443-pvz7dll9	255	4	a	a	DT
cord-023443-pvz7dll9	255	5	response	response	NN
cord-023443-pvz7dll9	255	6	peaked	peak	VBD
cord-023443-pvz7dll9	255	7	between	between	IN
cord-023443-pvz7dll9	255	8	3	3	CD
cord-023443-pvz7dll9	255	9	and	and	CC
cord-023443-pvz7dll9	255	10	4	4	CD
cord-023443-pvz7dll9	255	11	h	h	NN
cord-023443-pvz7dll9	255	12	at	at	IN
cord-023443-pvz7dll9	255	13	38.5	38.5	CD
cord-023443-pvz7dll9	255	14	C.	C.	NNP
cord-023443-pvz7dll9	255	15	A	A	NNP
cord-023443-pvz7dll9	255	16	dose	dose	NN
cord-023443-pvz7dll9	255	17	in	in	IN
cord-023443-pvz7dll9	255	18	the	the	DT
cord-023443-pvz7dll9	255	19	range	range	NN
cord-023443-pvz7dll9	255	20	of	of	IN
cord-023443-pvz7dll9	255	21	5	5	CD
cord-023443-pvz7dll9	255	22	-	-	SYM
cord-023443-pvz7dll9	255	23	10	10	CD
cord-023443-pvz7dll9	255	24	g	g	NN
cord-023443-pvz7dll9	255	25	of	of	IN
cord-023443-pvz7dll9	255	26	E.	E.	NNP
cord-023443-pvz7dll9	255	27	coli	coli	NNS
cord-023443-pvz7dll9	255	28	lipopolysaccharide	lipopolysaccharide	NN
cord-023443-pvz7dll9	255	29	(	(	-LRB-
cord-023443-pvz7dll9	255	30	LPS)/ml	lps)/ml	CD
cord-023443-pvz7dll9	255	31	whole	whole	JJ
cord-023443-pvz7dll9	255	32	blood	blood	NN
cord-023443-pvz7dll9	255	33	was	be	VBD
cord-023443-pvz7dll9	255	34	found	find	VBN
cord-023443-pvz7dll9	255	35	to	to	TO
cord-023443-pvz7dll9	255	36	give	give	VB
cord-023443-pvz7dll9	255	37	the	the	DT
cord-023443-pvz7dll9	255	38	maximum	maximum	JJ
cord-023443-pvz7dll9	255	39	TNF	TNF	NNP
cord-023443-pvz7dll9	255	40	-	-	:
cord-023443-pvz7dll9	255	41	a	a	DT
cord-023443-pvz7dll9	255	42	response	response	NN
cord-023443-pvz7dll9	255	43	.	.	.
cord-023443-pvz7dll9	256	1	Thirty	thirty	CD
cord-023443-pvz7dll9	256	2	-	-	HYPH
cord-023443-pvz7dll9	256	3	eight	eight	CD
cord-023443-pvz7dll9	256	4	Danish	Danish	NNP
cord-023443-pvz7dll9	256	5	-	-	HYPH
cord-023443-pvz7dll9	256	6	Holstein	Holstein	NNP
cord-023443-pvz7dll9	256	7	dairy	dairy	NN
cord-023443-pvz7dll9	256	8	cows	cow	NNS
cord-023443-pvz7dll9	256	9	were	be	VBD
cord-023443-pvz7dll9	256	10	investigated	investigate	VBN
cord-023443-pvz7dll9	256	11	for	for	IN
cord-023443-pvz7dll9	256	12	their	-PRON-	PRP$
cord-023443-pvz7dll9	256	13	TNF	TNF	NNP
cord-023443-pvz7dll9	256	14	-	-	:
cord-023443-pvz7dll9	256	15	a	a	DT
cord-023443-pvz7dll9	256	16	responsiveness	responsiveness	NN
cord-023443-pvz7dll9	256	17	ex	ex	FW
cord-023443-pvz7dll9	256	18	vivo	vivo	NN
cord-023443-pvz7dll9	256	19	in	in	IN
cord-023443-pvz7dll9	256	20	the	the	DT
cord-023443-pvz7dll9	256	21	periparturient	periparturient	JJ
cord-023443-pvz7dll9	256	22	period	period	NN
cord-023443-pvz7dll9	256	23	.	.	.
cord-023443-pvz7dll9	257	1	Heparin	Heparin	NNP
cord-023443-pvz7dll9	257	2	-	-	HYPH
cord-023443-pvz7dll9	257	3	stabilized	stabilize	VBN
cord-023443-pvz7dll9	257	4	blood	blood	NN
cord-023443-pvz7dll9	257	5	samples	sample	NNS
cord-023443-pvz7dll9	257	6	were	be	VBD
cord-023443-pvz7dll9	257	7	collected	collect	VBN
cord-023443-pvz7dll9	257	8	seven	seven	CD
cord-023443-pvz7dll9	257	9	times	time	NNS
cord-023443-pvz7dll9	257	10	over	over	IN
cord-023443-pvz7dll9	257	11	a	a	DT
cord-023443-pvz7dll9	257	12	period	period	NN
cord-023443-pvz7dll9	257	13	of	of	IN
cord-023443-pvz7dll9	257	14	4	4	CD
cord-023443-pvz7dll9	257	15	months	month	NNS
cord-023443-pvz7dll9	257	16	(	(	-LRB-
cord-023443-pvz7dll9	257	17	weeks	week	NNS
cord-023443-pvz7dll9	257	18	À3	à3	CD
cord-023443-pvz7dll9	257	19	,	,	,
cord-023443-pvz7dll9	257	20	À1	À1	NNP
cord-023443-pvz7dll9	257	21	,	,	,
cord-023443-pvz7dll9	257	22	2	2	CD
cord-023443-pvz7dll9	257	23	,	,	,
cord-023443-pvz7dll9	257	24	3	3	CD
cord-023443-pvz7dll9	257	25	,	,	,
cord-023443-pvz7dll9	257	26	5	5	CD
cord-023443-pvz7dll9	257	27	,	,	,
cord-023443-pvz7dll9	257	28	9	9	CD
cord-023443-pvz7dll9	257	29	and	and	CC
cord-023443-pvz7dll9	257	30	13	13	CD
cord-023443-pvz7dll9	257	31	around	around	IN
cord-023443-pvz7dll9	257	32	calving	calving	NN
cord-023443-pvz7dll9	257	33	)	)	-RRB-
cord-023443-pvz7dll9	257	34	and	and	CC
cord-023443-pvz7dll9	257	35	stimulated	stimulate	VBD
cord-023443-pvz7dll9	257	36	with	with	IN
cord-023443-pvz7dll9	257	37	5	5	CD
cord-023443-pvz7dll9	257	38	g	g	NN
cord-023443-pvz7dll9	257	39	/	/	SYM
cord-023443-pvz7dll9	257	40	ml	ml	NN
cord-023443-pvz7dll9	257	41	of	of	IN
cord-023443-pvz7dll9	257	42	E.	E.	NNP
cord-023443-pvz7dll9	257	43	coli	coli	VBZ
cord-023443-pvz7dll9	257	44	LPS	lp	NNS
cord-023443-pvz7dll9	257	45	.	.	.
cord-023443-pvz7dll9	258	1	Indeed	indeed	RB
cord-023443-pvz7dll9	258	2	,	,	,
cord-023443-pvz7dll9	258	3	fluctuations	fluctuation	NNS
cord-023443-pvz7dll9	258	4	in	in	IN
cord-023443-pvz7dll9	258	5	the	the	DT
cord-023443-pvz7dll9	258	6	TNF	TNF	NNP
cord-023443-pvz7dll9	258	7	-	-	:
cord-023443-pvz7dll9	258	8	a	a	DT
cord-023443-pvz7dll9	258	9	responsiveness	responsiveness	NN
cord-023443-pvz7dll9	258	10	occurred	occur	VBD
cord-023443-pvz7dll9	258	11	over	over	IN
cord-023443-pvz7dll9	258	12	time	time	NN
cord-023443-pvz7dll9	258	13	.	.	.
cord-023443-pvz7dll9	259	1	Moreover	moreover	RB
cord-023443-pvz7dll9	259	2	,	,	,
cord-023443-pvz7dll9	259	3	the	the	DT
cord-023443-pvz7dll9	259	4	mean	mean	JJ
cord-023443-pvz7dll9	259	5	TNF	TNF	NNP
cord-023443-pvz7dll9	259	6	-	-	:
cord-023443-pvz7dll9	259	7	a	a	DT
cord-023443-pvz7dll9	259	8	responsiveness	responsiveness	NN
cord-023443-pvz7dll9	259	9	of	of	IN
cord-023443-pvz7dll9	259	10	38	38	CD
cord-023443-pvz7dll9	259	11	cows	cow	NNS
cord-023443-pvz7dll9	259	12	was	be	VBD
cord-023443-pvz7dll9	259	13	found	find	VBN
cord-023443-pvz7dll9	259	14	to	to	TO
cord-023443-pvz7dll9	259	15	be	be	VB
cord-023443-pvz7dll9	259	16	significantly	significantly	RB
cord-023443-pvz7dll9	259	17	increased	increase	VBN
cord-023443-pvz7dll9	259	18	(	(	-LRB-
cord-023443-pvz7dll9	259	19	P	p	NN
cord-023443-pvz7dll9	259	20	<	<	XX
cord-023443-pvz7dll9	259	21	0.001	0.001	CD
cord-023443-pvz7dll9	259	22	)	)	-RRB-
cord-023443-pvz7dll9	259	23	in	in	IN
cord-023443-pvz7dll9	259	24	the	the	DT
cord-023443-pvz7dll9	259	25	weeks	week	NNS
cord-023443-pvz7dll9	259	26	close	close	JJ
cord-023443-pvz7dll9	259	27	to	to	IN
cord-023443-pvz7dll9	259	28	calving	calving	NN
cord-023443-pvz7dll9	259	29	.	.	.
cord-023443-pvz7dll9	260	1	However	however	RB
cord-023443-pvz7dll9	260	2	,	,	,
cord-023443-pvz7dll9	260	3	in	in	IN
cord-023443-pvz7dll9	260	4	the	the	DT
cord-023443-pvz7dll9	260	5	more	more	RBR
cord-023443-pvz7dll9	260	6	stabile	stabile	JJ
cord-023443-pvz7dll9	260	7	physiological	physiological	JJ
cord-023443-pvz7dll9	260	8	periods	period	NNS
cord-023443-pvz7dll9	260	9	,	,	,
cord-023443-pvz7dll9	260	10	some	some	DT
cord-023443-pvz7dll9	260	11	cows	cow	NNS
cord-023443-pvz7dll9	260	12	had	have	VBD
cord-023443-pvz7dll9	260	13	a	a	DT
cord-023443-pvz7dll9	260	14	consistently	consistently	RB
cord-023443-pvz7dll9	260	15	low	low	JJ
cord-023443-pvz7dll9	260	16	TNF	tnf	NN
cord-023443-pvz7dll9	260	17	-	-	:
cord-023443-pvz7dll9	260	18	a	a	DT
cord-023443-pvz7dll9	260	19	response	response	NN
cord-023443-pvz7dll9	260	20	,	,	,
cord-023443-pvz7dll9	260	21	whereas	whereas	IN
cord-023443-pvz7dll9	260	22	others	other	NNS
cord-023443-pvz7dll9	260	23	had	have	VBD
cord-023443-pvz7dll9	260	24	high	high	JJ
cord-023443-pvz7dll9	260	25	a	a	DT
cord-023443-pvz7dll9	260	26	TNF	TNF	NNP
cord-023443-pvz7dll9	260	27	-	-	:
cord-023443-pvz7dll9	260	28	a	a	DT
cord-023443-pvz7dll9	260	29	response	response	NN
cord-023443-pvz7dll9	260	30	.	.	.
cord-023443-pvz7dll9	261	1	We	-PRON-	PRP
cord-023443-pvz7dll9	261	2	are	be	VBP
cord-023443-pvz7dll9	261	3	currently	currently	RB
cord-023443-pvz7dll9	261	4	investigating	investigate	VBG
cord-023443-pvz7dll9	261	5	whether	whether	IN
cord-023443-pvz7dll9	261	6	high	high	JJ
cord-023443-pvz7dll9	261	7	and	and	CC
cord-023443-pvz7dll9	261	8	low	low	JJ
cord-023443-pvz7dll9	261	9	TNF	tnf	NN
cord-023443-pvz7dll9	261	10	-	-	:
cord-023443-pvz7dll9	261	11	a	a	DT
cord-023443-pvz7dll9	261	12	responders	responder	NNS
cord-023443-pvz7dll9	261	13	to	to	IN
cord-023443-pvz7dll9	261	14	E.	E.	NNP
cord-023443-pvz7dll9	261	15	coli	coli	VBZ
cord-023443-pvz7dll9	261	16	LPS	LPS	NNP
cord-023443-pvz7dll9	261	17	also	also	RB
cord-023443-pvz7dll9	261	18	exist	exist	VBP
cord-023443-pvz7dll9	261	19	in	in	IN
cord-023443-pvz7dll9	261	20	dairy	dairy	NN
cord-023443-pvz7dll9	261	21	cows	cow	NNS
cord-023443-pvz7dll9	261	22	in	in	IN
cord-023443-pvz7dll9	261	23	vivo	vivo	NN
cord-023443-pvz7dll9	261	24	.	.	.
cord-023443-pvz7dll9	262	1	Moreover	moreover	RB
cord-023443-pvz7dll9	262	2	,	,	,
cord-023443-pvz7dll9	262	3	the	the	DT
cord-023443-pvz7dll9	262	4	importance	importance	NN
cord-023443-pvz7dll9	262	5	of	of	IN
cord-023443-pvz7dll9	262	6	TNF	TNF	NNP
cord-023443-pvz7dll9	262	7	-	-	:
cord-023443-pvz7dll9	262	8	a	a	DT
cord-023443-pvz7dll9	262	9	responsiveness	responsiveness	NN
cord-023443-pvz7dll9	262	10	ex	ex	FW
cord-023443-pvz7dll9	262	11	vivo	vivo	NN
cord-023443-pvz7dll9	262	12	to	to	IN
cord-023443-pvz7dll9	262	13	dairy	dairy	NN
cord-023443-pvz7dll9	262	14	cows	cow	NNS
cord-023443-pvz7dll9	262	15	'	'	POS
cord-023443-pvz7dll9	262	16	susceptibility	susceptibility	NN
cord-023443-pvz7dll9	262	17	and	and	CC
cord-023443-pvz7dll9	262	18	clinical	clinical	JJ
cord-023443-pvz7dll9	262	19	response	response	NN
cord-023443-pvz7dll9	262	20	to	to	IN
cord-023443-pvz7dll9	262	21	experimental	experimental	JJ
cord-023443-pvz7dll9	262	22	E.	E.	NNP
cord-023443-pvz7dll9	262	23	coli	coli	VBZ
cord-023443-pvz7dll9	262	24	infections	infection	NNS
cord-023443-pvz7dll9	262	25	in	in	IN
cord-023443-pvz7dll9	262	26	the	the	DT
cord-023443-pvz7dll9	262	27	udder	udder	NN
cord-023443-pvz7dll9	262	28	is	be	VBZ
cord-023443-pvz7dll9	262	29	being	be	VBG
cord-023443-pvz7dll9	262	30	investigated	investigate	VBN
cord-023443-pvz7dll9	262	31	.	.	.
cord-023443-pvz7dll9	263	1	Coelomic	Coelomic	NNP
cord-023443-pvz7dll9	263	2	cytolytic	cytolytic	JJ
cord-023443-pvz7dll9	263	3	factor	factor	NN
cord-023443-pvz7dll9	263	4	(	(	-LRB-
cord-023443-pvz7dll9	263	5	CCF	CCF	NNP
cord-023443-pvz7dll9	263	6	)	)	-RRB-
cord-023443-pvz7dll9	263	7	is	be	VBZ
cord-023443-pvz7dll9	263	8	a	a	DT
cord-023443-pvz7dll9	263	9	42	42	CD
cord-023443-pvz7dll9	263	10	kDa	kDa	NNP
cord-023443-pvz7dll9	263	11	invertebrate	invertebrate	NN
cord-023443-pvz7dll9	263	12	pattern	pattern	NN
cord-023443-pvz7dll9	263	13	recognition	recognition	NN
cord-023443-pvz7dll9	263	14	molecule	molecule	NN
cord-023443-pvz7dll9	263	15	isolated	isolate	VBN
cord-023443-pvz7dll9	263	16	from	from	IN
cord-023443-pvz7dll9	263	17	the	the	DT
cord-023443-pvz7dll9	263	18	coelomic	coelomic	NNP
cord-023443-pvz7dll9	263	19	fluid	fluid	NN
cord-023443-pvz7dll9	263	20	of	of	IN
cord-023443-pvz7dll9	263	21	the	the	DT
cord-023443-pvz7dll9	263	22	earthworm	earthworm	NN
cord-023443-pvz7dll9	263	23	Eisenia	Eisenia	NNP
cord-023443-pvz7dll9	263	24	foetida	foetida	NNP
cord-023443-pvz7dll9	263	25	(	(	-LRB-
cord-023443-pvz7dll9	263	26	Oligochaeta	Oligochaeta	NNP
cord-023443-pvz7dll9	263	27	,	,	,
cord-023443-pvz7dll9	263	28	Annelida	Annelida	NNP
cord-023443-pvz7dll9	263	29	)	)	-RRB-
cord-023443-pvz7dll9	263	30	.	.	.
cord-023443-pvz7dll9	264	1	CCF	CCF	NNP
cord-023443-pvz7dll9	264	2	displays	display	VBZ
cord-023443-pvz7dll9	264	3	a	a	DT
cord-023443-pvz7dll9	264	4	number	number	NN
cord-023443-pvz7dll9	264	5	of	of	IN
cord-023443-pvz7dll9	264	6	similarities	similarity	NNS
cord-023443-pvz7dll9	264	7	with	with	IN
cord-023443-pvz7dll9	264	8	the	the	DT
cord-023443-pvz7dll9	264	9	mammalian	mammalian	JJ
cord-023443-pvz7dll9	264	10	cytokine	cytokine	NN
cord-023443-pvz7dll9	264	11	tumour	tumour	NN
cord-023443-pvz7dll9	264	12	necrosis	necrosis	NN
cord-023443-pvz7dll9	264	13	factor	factor	NN
cord-023443-pvz7dll9	264	14	-	-	:
cord-023443-pvz7dll9	264	15	a	a	NN
cord-023443-pvz7dll9	264	16	(	(	-LRB-
cord-023443-pvz7dll9	264	17	TNFa	TNFa	NNP
cord-023443-pvz7dll9	264	18	)	)	-RRB-
cord-023443-pvz7dll9	264	19	as	as	IN
cord-023443-pvz7dll9	264	20	a	a	DT
cord-023443-pvz7dll9	264	21	result	result	NN
cord-023443-pvz7dll9	264	22	of	of	IN
cord-023443-pvz7dll9	264	23	a	a	DT
cord-023443-pvz7dll9	264	24	shared	shared	JJ
cord-023443-pvz7dll9	264	25	N	N	NNP
cord-023443-pvz7dll9	264	26	,	,	,
cord-023443-pvz7dll9	264	27	N	n	CD
cord-023443-pvz7dll9	264	28	0	0	CD
cord-023443-pvz7dll9	264	29	-diacetylchitobiose	-diacetylchitobiose	HYPH
cord-023443-pvz7dll9	264	30	lectin	lectin	NN
cord-023443-pvz7dll9	264	31	-	-	HYPH
cord-023443-pvz7dll9	264	32	like	like	JJ
cord-023443-pvz7dll9	264	33	domain	domain	NN
cord-023443-pvz7dll9	264	34	.	.	.
cord-023443-pvz7dll9	265	1	However	however	RB
cord-023443-pvz7dll9	265	2	,	,	,
cord-023443-pvz7dll9	265	3	these	these	DT
cord-023443-pvz7dll9	265	4	similarities	similarity	NNS
cord-023443-pvz7dll9	265	5	are	be	VBP
cord-023443-pvz7dll9	265	6	solely	solely	RB
cord-023443-pvz7dll9	265	7	functional	functional	JJ
cord-023443-pvz7dll9	265	8	and	and	CC
cord-023443-pvz7dll9	265	9	are	be	VBP
cord-023443-pvz7dll9	265	10	not	not	RB
cord-023443-pvz7dll9	265	11	based	base	VBN
cord-023443-pvz7dll9	265	12	on	on	IN
cord-023443-pvz7dll9	265	13	any	any	DT
cord-023443-pvz7dll9	265	14	(	(	-LRB-
cord-023443-pvz7dll9	265	15	DNA	dna	NN
cord-023443-pvz7dll9	265	16	or	or	CC
cord-023443-pvz7dll9	265	17	amino	amino	NN
cord-023443-pvz7dll9	265	18	acid	acid	NN
cord-023443-pvz7dll9	265	19	)	)	-RRB-
cord-023443-pvz7dll9	265	20	sequence	sequence	NN
cord-023443-pvz7dll9	265	21	homology	homology	NN
cord-023443-pvz7dll9	265	22	,	,	,
cord-023443-pvz7dll9	265	23	thus	thus	RB
cord-023443-pvz7dll9	265	24	suggesting	suggest	VBG
cord-023443-pvz7dll9	265	25	a	a	DT
cord-023443-pvz7dll9	265	26	form	form	NN
cord-023443-pvz7dll9	265	27	of	of	IN
cord-023443-pvz7dll9	265	28	convergent	convergent	JJ
cord-023443-pvz7dll9	265	29	evolution	evolution	NN
cord-023443-pvz7dll9	265	30	.	.	.
cord-023443-pvz7dll9	266	1	In	in	IN
cord-023443-pvz7dll9	266	2	particular	particular	JJ
cord-023443-pvz7dll9	266	3	,	,	,
cord-023443-pvz7dll9	266	4	the	the	DT
cord-023443-pvz7dll9	266	5	lectin	lectin	NN
cord-023443-pvz7dll9	266	6	-	-	HYPH
cord-023443-pvz7dll9	266	7	like	like	JJ
cord-023443-pvz7dll9	266	8	domain	domain	NN
cord-023443-pvz7dll9	266	9	of	of	IN
cord-023443-pvz7dll9	266	10	TNF	TNF	NNP
cord-023443-pvz7dll9	266	11	-	-	:
cord-023443-pvz7dll9	266	12	a	a	NNP
cord-023443-pvz7dll9	266	13	has	have	VBZ
cord-023443-pvz7dll9	266	14	been	be	VBN
cord-023443-pvz7dll9	266	15	shown	show	VBN
cord-023443-pvz7dll9	266	16	to	to	TO
cord-023443-pvz7dll9	266	17	induce	induce	VB
cord-023443-pvz7dll9	266	18	membrane	membrane	NN
cord-023443-pvz7dll9	266	19	depolarization	depolarization	NN
cord-023443-pvz7dll9	266	20	in	in	IN
cord-023443-pvz7dll9	266	21	various	various	JJ
cord-023443-pvz7dll9	266	22	mammalian	mammalian	JJ
cord-023443-pvz7dll9	266	23	cell	cell	NN
cord-023443-pvz7dll9	266	24	types	type	NNS
cord-023443-pvz7dll9	266	25	,	,	,
cord-023443-pvz7dll9	266	26	through	through	IN
cord-023443-pvz7dll9	266	27	interactions	interaction	NNS
cord-023443-pvz7dll9	266	28	with	with	IN
cord-023443-pvz7dll9	266	29	endogenous	endogenous	JJ
cord-023443-pvz7dll9	266	30	amiloride	amiloride	NN
cord-023443-pvz7dll9	266	31	-	-	HYPH
cord-023443-pvz7dll9	266	32	sensitive	sensitive	JJ
cord-023443-pvz7dll9	266	33	ion	ion	NN
cord-023443-pvz7dll9	266	34	channels	channel	NNS
cord-023443-pvz7dll9	266	35	.	.	.
cord-023443-pvz7dll9	267	1	This	this	DT
cord-023443-pvz7dll9	267	2	nonreceptor	nonreceptor	RB
cord-023443-pvz7dll9	267	3	-	-	HYPH
cord-023443-pvz7dll9	267	4	mediated	mediate	VBN
cord-023443-pvz7dll9	267	5	activity	activity	NN
cord-023443-pvz7dll9	267	6	of	of	IN
cord-023443-pvz7dll9	267	7	TNF	TNF	NNP
cord-023443-pvz7dll9	267	8	-	-	:
cord-023443-pvz7dll9	267	9	a	a	NNP
cord-023443-pvz7dll9	267	10	has	have	VBZ
cord-023443-pvz7dll9	267	11	been	be	VBN
cord-023443-pvz7dll9	267	12	reported	report	VBN
cord-023443-pvz7dll9	267	13	to	to	TO
cord-023443-pvz7dll9	267	14	be	be	VB
cord-023443-pvz7dll9	267	15	involved	involve	VBN
cord-023443-pvz7dll9	267	16	in	in	IN
cord-023443-pvz7dll9	267	17	the	the	DT
cord-023443-pvz7dll9	267	18	resorption	resorption	NN
cord-023443-pvz7dll9	267	19	of	of	IN
cord-023443-pvz7dll9	267	20	oedema	oedema	NN
cord-023443-pvz7dll9	267	21	.	.	.
cord-023443-pvz7dll9	268	1	Likewise	likewise	RB
cord-023443-pvz7dll9	268	2	,	,	,
cord-023443-pvz7dll9	268	3	the	the	DT
cord-023443-pvz7dll9	268	4	lectin	lectin	NN
cord-023443-pvz7dll9	268	5	-	-	HYPH
cord-023443-pvz7dll9	268	6	like	like	JJ
cord-023443-pvz7dll9	268	7	domain	domain	NN
cord-023443-pvz7dll9	268	8	of	of	IN
cord-023443-pvz7dll9	268	9	CCF	CCF	NNP
cord-023443-pvz7dll9	268	10	also	also	RB
cord-023443-pvz7dll9	268	11	induces	induce	VBZ
cord-023443-pvz7dll9	268	12	membrane	membrane	NN
cord-023443-pvz7dll9	268	13	depolarization	depolarization	NN
cord-023443-pvz7dll9	268	14	in	in	IN
cord-023443-pvz7dll9	268	15	mammalian	mammalian	JJ
cord-023443-pvz7dll9	268	16	cells	cell	NNS
cord-023443-pvz7dll9	268	17	.	.	.
cord-023443-pvz7dll9	269	1	Here	here	RB
cord-023443-pvz7dll9	269	2	,	,	,
cord-023443-pvz7dll9	269	3	we	-PRON-	PRP
cord-023443-pvz7dll9	269	4	show	show	VBP
cord-023443-pvz7dll9	269	5	that	that	IN
cord-023443-pvz7dll9	269	6	CCF	CCF	NNP
cord-023443-pvz7dll9	269	7	appears	appear	VBZ
cord-023443-pvz7dll9	269	8	to	to	TO
cord-023443-pvz7dll9	269	9	be	be	VB
cord-023443-pvz7dll9	269	10	able	able	JJ
cord-023443-pvz7dll9	269	11	to	to	TO
cord-023443-pvz7dll9	269	12	induce	induce	VB
cord-023443-pvz7dll9	269	13	oedema	oedema	NN
cord-023443-pvz7dll9	269	14	resorption	resorption	NN
cord-023443-pvz7dll9	269	15	in	in	IN
cord-023443-pvz7dll9	269	16	an	an	DT
cord-023443-pvz7dll9	269	17	alveolar	alveolar	JJ
cord-023443-pvz7dll9	269	18	epithelial	epithelial	JJ
cord-023443-pvz7dll9	269	19	cell	cell	NN
cord-023443-pvz7dll9	269	20	line	line	NN
cord-023443-pvz7dll9	269	21	through	through	IN
cord-023443-pvz7dll9	269	22	its	-PRON-	PRP$
cord-023443-pvz7dll9	269	23	lectin	lectin	NN
cord-023443-pvz7dll9	269	24	-	-	HYPH
cord-023443-pvz7dll9	269	25	like	like	JJ
cord-023443-pvz7dll9	269	26	domain	domain	NN
cord-023443-pvz7dll9	269	27	.	.	.
cord-023443-pvz7dll9	270	1	This	this	DT
cord-023443-pvz7dll9	270	2	lectin	lectin	NN
cord-023443-pvz7dll9	270	3	-	-	HYPH
cord-023443-pvz7dll9	270	4	like	like	JJ
cord-023443-pvz7dll9	270	5	domain	domain	NN
cord-023443-pvz7dll9	270	6	of	of	IN
cord-023443-pvz7dll9	270	7	CCF	CCF	NNP
cord-023443-pvz7dll9	270	8	interacts	interact	VBZ
cord-023443-pvz7dll9	270	9	(	(	-LRB-
cord-023443-pvz7dll9	270	10	directly	directly	RB
cord-023443-pvz7dll9	270	11	or	or	CC
cord-023443-pvz7dll9	270	12	indirectly	indirectly	RB
cord-023443-pvz7dll9	270	13	)	)	-RRB-
cord-023443-pvz7dll9	270	14	with	with	IN
cord-023443-pvz7dll9	270	15	endogenous	endogenous	JJ
cord-023443-pvz7dll9	270	16	sodium	sodium	NN
cord-023443-pvz7dll9	270	17	and/or	and/or	CC
cord-023443-pvz7dll9	270	18	chloride	chloride	NN
cord-023443-pvz7dll9	270	19	channels	channel	NNS
cord-023443-pvz7dll9	270	20	,	,	,
cord-023443-pvz7dll9	270	21	and	and	CC
cord-023443-pvz7dll9	270	22	not	not	RB
cord-023443-pvz7dll9	270	23	potassium	potassium	NN
cord-023443-pvz7dll9	270	24	channels	channel	NNS
cord-023443-pvz7dll9	270	25	,	,	,
cord-023443-pvz7dll9	270	26	on	on	IN
cord-023443-pvz7dll9	270	27	mammalian	mammalian	JJ
cord-023443-pvz7dll9	270	28	cells	cell	NNS
cord-023443-pvz7dll9	270	29	.	.	.
cord-023443-pvz7dll9	271	1	Additionally	additionally	RB
cord-023443-pvz7dll9	271	2	,	,	,
cord-023443-pvz7dll9	271	3	we	-PRON-	PRP
cord-023443-pvz7dll9	271	4	suggest	suggest	VBP
cord-023443-pvz7dll9	271	5	that	that	IN
cord-023443-pvz7dll9	271	6	the	the	DT
cord-023443-pvz7dll9	271	7	JNK	JNK	NNP
cord-023443-pvz7dll9	271	8	/	/	SYM
cord-023443-pvz7dll9	271	9	SAPK	SAPK	NNP
cord-023443-pvz7dll9	271	10	and	and	CC
cord-023443-pvz7dll9	271	11	Erk1/2	Erk1/2	NNP
cord-023443-pvz7dll9	271	12	pathways	pathway	NNS
cord-023443-pvz7dll9	271	13	are	be	VBP
cord-023443-pvz7dll9	271	14	involved	involve	VBN
cord-023443-pvz7dll9	271	15	in	in	IN
cord-023443-pvz7dll9	271	16	CCF	CCF	NNP
cord-023443-pvz7dll9	271	17	-	-	HYPH
cord-023443-pvz7dll9	271	18	induced	induce	VBN
cord-023443-pvz7dll9	271	19	macrophage	macrophage	NN
cord-023443-pvz7dll9	271	20	activation	activation	NN
cord-023443-pvz7dll9	271	21	.	.	.
cord-023443-pvz7dll9	272	1	These	these	DT
cord-023443-pvz7dll9	272	2	results	result	NNS
cord-023443-pvz7dll9	272	3	further	further	RB
cord-023443-pvz7dll9	272	4	establish	establish	VBP
cord-023443-pvz7dll9	272	5	the	the	DT
cord-023443-pvz7dll9	272	6	functional	functional	JJ
cord-023443-pvz7dll9	272	7	analogy	analogy	NN
cord-023443-pvz7dll9	272	8	between	between	IN
cord-023443-pvz7dll9	272	9	an	an	DT
cord-023443-pvz7dll9	272	10	invertebrate	invertebrate	JJ
cord-023443-pvz7dll9	272	11	pattern	pattern	NN
cord-023443-pvz7dll9	272	12	recognition	recognition	NN
cord-023443-pvz7dll9	272	13	molecule	molecule	NN
cord-023443-pvz7dll9	272	14	and	and	CC
cord-023443-pvz7dll9	272	15	a	a	DT
cord-023443-pvz7dll9	272	16	mammalian	mammalian	JJ
cord-023443-pvz7dll9	272	17	cytokine	cytokine	NN
cord-023443-pvz7dll9	272	18	and	and	CC
cord-023443-pvz7dll9	272	19	,	,	,
cord-023443-pvz7dll9	272	20	from	from	IN
cord-023443-pvz7dll9	272	21	a	a	DT
cord-023443-pvz7dll9	272	22	more	more	RBR
cord-023443-pvz7dll9	272	23	applied	applied	JJ
cord-023443-pvz7dll9	272	24	point	point	NN
cord-023443-pvz7dll9	272	25	of	of	IN
cord-023443-pvz7dll9	272	26	view	view	NN
cord-023443-pvz7dll9	272	27	,	,	,
cord-023443-pvz7dll9	272	28	suggest	suggest	VBP
cord-023443-pvz7dll9	272	29	the	the	DT
cord-023443-pvz7dll9	272	30	possibility	possibility	NN
cord-023443-pvz7dll9	272	31	of	of	IN
cord-023443-pvz7dll9	272	32	utilizing	utilize	VBG
cord-023443-pvz7dll9	272	33	CCF	CCF	NNP
cord-023443-pvz7dll9	272	34	in	in	IN
cord-023443-pvz7dll9	272	35	the	the	DT
cord-023443-pvz7dll9	272	36	treatment	treatment	NN
cord-023443-pvz7dll9	272	37	of	of	IN
cord-023443-pvz7dll9	272	38	oedema	oedema	NN
cord-023443-pvz7dll9	272	39	.	.	.
cord-023443-pvz7dll9	273	1	Release	Release	NNP
cord-023443-pvz7dll9	273	2	of	of	IN
cord-023443-pvz7dll9	273	3	sVEGF	svegf	NN
cord-023443-pvz7dll9	273	4	and	and	CC
cord-023443-pvz7dll9	273	5	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	273	6	from	from	IN
cord-023443-pvz7dll9	273	7	White	White	NNP
cord-023443-pvz7dll9	273	8	Blood	Blood	NNP
cord-023443-pvz7dll9	273	9	Cells	Cells	NNPS
cord-023443-pvz7dll9	273	10	and	and	CC
cord-023443-pvz7dll9	273	11	Platelets	platelet	NNS
cord-023443-pvz7dll9	273	12	During	during	IN
cord-023443-pvz7dll9	273	13	Surgery	surgery	NN
cord-023443-pvz7dll9	273	14	and	and	CC
cord-023443-pvz7dll9	273	15	Stimulation	stimulation	NN
cord-023443-pvz7dll9	273	16	with	with	IN
cord-023443-pvz7dll9	273	17	Bacterial	bacterial	JJ
cord-023443-pvz7dll9	273	18	Antigens	antigen	NNS
cord-023443-pvz7dll9	273	19	Introduction	introduction	NN
cord-023443-pvz7dll9	273	20	:	:	:
cord-023443-pvz7dll9	274	1	The	the	DT
cord-023443-pvz7dll9	274	2	influence	influence	NN
cord-023443-pvz7dll9	274	3	of	of	IN
cord-023443-pvz7dll9	274	4	surgery	surgery	NN
cord-023443-pvz7dll9	274	5	on	on	IN
cord-023443-pvz7dll9	274	6	release	release	NN
cord-023443-pvz7dll9	274	7	of	of	IN
cord-023443-pvz7dll9	274	8	soluble	soluble	JJ
cord-023443-pvz7dll9	274	9	vascular	vascular	JJ
cord-023443-pvz7dll9	274	10	endothelial	endothelial	JJ
cord-023443-pvz7dll9	274	11	growth	growth	NN
cord-023443-pvz7dll9	274	12	factor	factor	NN
cord-023443-pvz7dll9	274	13	(	(	-LRB-
cord-023443-pvz7dll9	274	14	sVEGF	sVEGF	NNP
cord-023443-pvz7dll9	274	15	)	)	-RRB-
cord-023443-pvz7dll9	274	16	and	and	CC
cord-023443-pvz7dll9	274	17	the	the	DT
cord-023443-pvz7dll9	274	18	soluble	soluble	JJ
cord-023443-pvz7dll9	274	19	vascular	vascular	JJ
cord-023443-pvz7dll9	274	20	endothelial	endothelial	JJ
cord-023443-pvz7dll9	274	21	growth	growth	NN
cord-023443-pvz7dll9	274	22	factor	factor	NN
cord-023443-pvz7dll9	274	23	inhibitory	inhibitory	JJ
cord-023443-pvz7dll9	274	24	receptor	receptor	NN
cord-023443-pvz7dll9	274	25	1	1	CD
cord-023443-pvz7dll9	274	26	(	(	-LRB-
cord-023443-pvz7dll9	274	27	sVEGFR1	sVEGFR1	NNP
cord-023443-pvz7dll9	274	28	)	)	-RRB-
cord-023443-pvz7dll9	274	29	is	be	VBZ
cord-023443-pvz7dll9	274	30	unknown	unknown	JJ
cord-023443-pvz7dll9	274	31	.	.	.
cord-023443-pvz7dll9	275	1	We	-PRON-	PRP
cord-023443-pvz7dll9	275	2	studied	study	VBD
cord-023443-pvz7dll9	275	3	the	the	DT
cord-023443-pvz7dll9	275	4	effect	effect	NN
cord-023443-pvz7dll9	275	5	of	of	IN
cord-023443-pvz7dll9	275	6	major	major	JJ
cord-023443-pvz7dll9	275	7	and	and	CC
cord-023443-pvz7dll9	275	8	minor	minor	JJ
cord-023443-pvz7dll9	275	9	surgery	surgery	NN
cord-023443-pvz7dll9	275	10	on	on	IN
cord-023443-pvz7dll9	275	11	potential	potential	JJ
cord-023443-pvz7dll9	275	12	variations	variation	NNS
cord-023443-pvz7dll9	275	13	in	in	IN
cord-023443-pvz7dll9	275	14	sVEGF	svegf	NN
cord-023443-pvz7dll9	275	15	and	and	CC
cord-023443-pvz7dll9	275	16	sVEGFR1	svegfr1	JJ
cord-023443-pvz7dll9	275	17	concentrations	concentration	NNS
cord-023443-pvz7dll9	275	18	in	in	IN
cord-023443-pvz7dll9	275	19	vivo	vivo	NN
cord-023443-pvz7dll9	275	20	and	and	CC
cord-023443-pvz7dll9	275	21	on	on	IN
cord-023443-pvz7dll9	275	22	bacterial	bacterial	JJ
cord-023443-pvz7dll9	275	23	antigen	antigen	NN
cord-023443-pvz7dll9	275	24	-	-	HYPH
cord-023443-pvz7dll9	275	25	induced	induce	VBN
cord-023443-pvz7dll9	275	26	release	release	NN
cord-023443-pvz7dll9	275	27	of	of	IN
cord-023443-pvz7dll9	275	28	sVEGF	sVEGF	NNP
cord-023443-pvz7dll9	275	29	and	and	CC
cord-023443-pvz7dll9	275	30	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	275	31	from	from	IN
cord-023443-pvz7dll9	275	32	whole	whole	JJ
cord-023443-pvz7dll9	275	33	blood	blood	NN
cord-023443-pvz7dll9	275	34	in	in	IN
cord-023443-pvz7dll9	275	35	vitro	vitro	FW
cord-023443-pvz7dll9	275	36	.	.	.
cord-023443-pvz7dll9	276	1	Methods	method	NNS
cord-023443-pvz7dll9	276	2	:	:	:
cord-023443-pvz7dll9	276	3	Sixty	sixty	CD
cord-023443-pvz7dll9	276	4	-	-	HYPH
cord-023443-pvz7dll9	276	5	one	one	CD
cord-023443-pvz7dll9	276	6	patients	patient	NNS
cord-023443-pvz7dll9	276	7	with	with	IN
cord-023443-pvz7dll9	276	8	abdominal	abdominal	JJ
cord-023443-pvz7dll9	276	9	diseases	disease	NNS
cord-023443-pvz7dll9	276	10	undergoing	undergo	VBG
cord-023443-pvz7dll9	276	11	five	five	CD
cord-023443-pvz7dll9	276	12	different	different	JJ
cord-023443-pvz7dll9	276	13	surgical	surgical	JJ
cord-023443-pvz7dll9	276	14	procedures	procedure	NNS
cord-023443-pvz7dll9	276	15	were	be	VBD
cord-023443-pvz7dll9	276	16	included	include	VBN
cord-023443-pvz7dll9	276	17	.	.	.
cord-023443-pvz7dll9	277	1	Blood	blood	NN
cord-023443-pvz7dll9	277	2	samples	sample	NNS
cord-023443-pvz7dll9	277	3	were	be	VBD
cord-023443-pvz7dll9	277	4	drawn	draw	VBN
cord-023443-pvz7dll9	277	5	from	from	IN
cord-023443-pvz7dll9	277	6	anaesthetized	anaesthetized	JJ
cord-023443-pvz7dll9	277	7	patients	patient	NNS
cord-023443-pvz7dll9	277	8	before	before	IN
cord-023443-pvz7dll9	277	9	and	and	CC
cord-023443-pvz7dll9	277	10	after	after	IN
cord-023443-pvz7dll9	277	11	the	the	DT
cord-023443-pvz7dll9	277	12	operation	operation	NN
cord-023443-pvz7dll9	277	13	.	.	.
cord-023443-pvz7dll9	278	1	White	white	JJ
cord-023443-pvz7dll9	278	2	blood	blood	NN
cord-023443-pvz7dll9	278	3	cells	cell	NNS
cord-023443-pvz7dll9	278	4	and	and	CC
cord-023443-pvz7dll9	278	5	platelets	platelet	NNS
cord-023443-pvz7dll9	278	6	were	be	VBD
cord-023443-pvz7dll9	278	7	counted	count	VBN
cord-023443-pvz7dll9	278	8	,	,	,
cord-023443-pvz7dll9	278	9	and	and	CC
cord-023443-pvz7dll9	278	10	plasma	plasma	NN
cord-023443-pvz7dll9	278	11	sVEGF	svegf	NN
cord-023443-pvz7dll9	278	12	and	and	CC
cord-023443-pvz7dll9	278	13	sVEGFR1	sVEGFR1	NNP
cord-023443-pvz7dll9	278	14	was	be	VBD
cord-023443-pvz7dll9	278	15	determined	determine	VBN
cord-023443-pvz7dll9	278	16	by	by	IN
cord-023443-pvz7dll9	278	17	an	an	DT
cord-023443-pvz7dll9	278	18	ELISA	ELISA	NNP
cord-023443-pvz7dll9	278	19	method	method	NN
cord-023443-pvz7dll9	278	20	.	.	.
cord-023443-pvz7dll9	279	1	Whole	whole	JJ
cord-023443-pvz7dll9	279	2	blood	blood	NN
cord-023443-pvz7dll9	279	3	from	from	IN
cord-023443-pvz7dll9	279	4	each	each	DT
cord-023443-pvz7dll9	279	5	blood	blood	NN
cord-023443-pvz7dll9	279	6	sample	sample	NN
cord-023443-pvz7dll9	279	7	was	be	VBD
cord-023443-pvz7dll9	279	8	stimulated	stimulate	VBN
cord-023443-pvz7dll9	279	9	in	in	IN
cord-023443-pvz7dll9	279	10	vitro	vitro	FW
cord-023443-pvz7dll9	279	11	with	with	IN
cord-023443-pvz7dll9	279	12	bacteria	bacteria	NNS
cord-023443-pvz7dll9	279	13	-	-	HYPH
cord-023443-pvz7dll9	279	14	derived	derive	VBN
cord-023443-pvz7dll9	279	15	antigens	antigen	NNS
cord-023443-pvz7dll9	279	16	(	(	-LRB-
cord-023443-pvz7dll9	279	17	LPS	LPS	NNP
cord-023443-pvz7dll9	279	18	or	or	CC
cord-023443-pvz7dll9	279	19	protein	protein	NN
cord-023443-pvz7dll9	279	20	-	-	HYPH
cord-023443-pvz7dll9	279	21	A	a	NN
cord-023443-pvz7dll9	279	22	)	)	-RRB-
cord-023443-pvz7dll9	279	23	and	and	CC
cord-023443-pvz7dll9	279	24	sVEGF	svegf	NN
cord-023443-pvz7dll9	279	25	and	and	CC
cord-023443-pvz7dll9	279	26	sVEGFR1	svegfr1	JJ
cord-023443-pvz7dll9	279	27	levels	level	NNS
cord-023443-pvz7dll9	279	28	were	be	VBD
cord-023443-pvz7dll9	279	29	subsequently	subsequently	RB
cord-023443-pvz7dll9	279	30	determined	determine	VBN
cord-023443-pvz7dll9	279	31	in	in	IN
cord-023443-pvz7dll9	279	32	the	the	DT
cord-023443-pvz7dll9	279	33	supernatants	supernatant	NNS
cord-023443-pvz7dll9	279	34	.	.	.
cord-023443-pvz7dll9	280	1	Stimulation	stimulation	NN
cord-023443-pvz7dll9	280	2	with	with	IN
cord-023443-pvz7dll9	280	3	isotonic	isotonic	JJ
cord-023443-pvz7dll9	280	4	saline	saline	NN
cord-023443-pvz7dll9	280	5	served	serve	VBD
cord-023443-pvz7dll9	280	6	as	as	IN
cord-023443-pvz7dll9	280	7	control	control	NN
cord-023443-pvz7dll9	280	8	assay	assay	NN
cord-023443-pvz7dll9	280	9	.	.	.
cord-023443-pvz7dll9	280	10	 	 	_SP
cord-023443-pvz7dll9	281	1	Neither	neither	DT
cord-023443-pvz7dll9	281	2	sVEGF	svegf	NN
cord-023443-pvz7dll9	281	3	or	or	CC
cord-023443-pvz7dll9	281	4	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	281	5	in	in	IN
cord-023443-pvz7dll9	281	6	plasma	plasma	NN
cord-023443-pvz7dll9	281	7	changed	change	VBN
cord-023443-pvz7dll9	281	8	during	during	IN
cord-023443-pvz7dll9	281	9	surgery	surgery	NN
cord-023443-pvz7dll9	281	10	.	.	.
cord-023443-pvz7dll9	282	1	In	in	IN
cord-023443-pvz7dll9	282	2	vitro	vitro	FW
cord-023443-pvz7dll9	282	3	stimulation	stimulation	NN
cord-023443-pvz7dll9	282	4	of	of	IN
cord-023443-pvz7dll9	282	5	blood	blood	NN
cord-023443-pvz7dll9	282	6	samples	sample	NNS
cord-023443-pvz7dll9	282	7	with	with	IN
cord-023443-pvz7dll9	282	8	bacteria	bacteria	NNS
cord-023443-pvz7dll9	282	9	-	-	HYPH
cord-023443-pvz7dll9	282	10	derived	derive	VBN
cord-023443-pvz7dll9	282	11	antigens	antigen	NNS
cord-023443-pvz7dll9	282	12	resulted	result	VBD
cord-023443-pvz7dll9	282	13	in	in	IN
cord-023443-pvz7dll9	282	14	a	a	DT
cord-023443-pvz7dll9	282	15	significant	significant	JJ
cord-023443-pvz7dll9	282	16	increase	increase	NN
cord-023443-pvz7dll9	282	17	in	in	IN
cord-023443-pvz7dll9	282	18	sVEGF	svegf	NN
cord-023443-pvz7dll9	283	1	(	(	-LRB-
cord-023443-pvz7dll9	283	2	P	p	NN
cord-023443-pvz7dll9	283	3	<	<	XX
cord-023443-pvz7dll9	283	4	0.0001	0.0001	CD
cord-023443-pvz7dll9	283	5	)	)	-RRB-
cord-023443-pvz7dll9	283	6	and	and	CC
cord-023443-pvz7dll9	283	7	a	a	DT
cord-023443-pvz7dll9	283	8	less	less	RBR
cord-023443-pvz7dll9	283	9	pronounced	pronounced	JJ
cord-023443-pvz7dll9	283	10	but	but	CC
cord-023443-pvz7dll9	283	11	still	still	RB
cord-023443-pvz7dll9	283	12	significant	significant	JJ
cord-023443-pvz7dll9	283	13	increase	increase	NN
cord-023443-pvz7dll9	283	14	in	in	IN
cord-023443-pvz7dll9	283	15	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	283	16	.	.	.
cord-023443-pvz7dll9	284	1	Release	Release	NNP
cord-023443-pvz7dll9	284	2	of	of	IN
cord-023443-pvz7dll9	284	3	sVEGF	svegf	NN
cord-023443-pvz7dll9	284	4	due	due	IN
cord-023443-pvz7dll9	284	5	to	to	IN
cord-023443-pvz7dll9	284	6	stimulation	stimulation	NN
cord-023443-pvz7dll9	284	7	was	be	VBD
cord-023443-pvz7dll9	284	8	significantly	significantly	RB
cord-023443-pvz7dll9	284	9	higher	high	JJR
cord-023443-pvz7dll9	284	10	after	after	IN
cord-023443-pvz7dll9	284	11	the	the	DT
cord-023443-pvz7dll9	284	12	operation	operation	NN
cord-023443-pvz7dll9	284	13	(	(	-LRB-
cord-023443-pvz7dll9	284	14	nonsignificant	nonsignificant	JJ
cord-023443-pvz7dll9	284	15	)	)	-RRB-
cord-023443-pvz7dll9	284	16	,	,	,
cord-023443-pvz7dll9	284	17	whereas	whereas	IN
cord-023443-pvz7dll9	284	18	sVEGFR1	sVEGFR1	NNP
cord-023443-pvz7dll9	284	19	release	release	NN
cord-023443-pvz7dll9	284	20	remained	remain	VBD
cord-023443-pvz7dll9	284	21	largely	largely	RB
cord-023443-pvz7dll9	284	22	unchanged	unchanged	JJ
cord-023443-pvz7dll9	284	23	after	after	IN
cord-023443-pvz7dll9	284	24	surgery	surgery	NN
cord-023443-pvz7dll9	284	25	.	.	.
cord-023443-pvz7dll9	285	1	Correlation	correlation	NN
cord-023443-pvz7dll9	285	2	between	between	IN
cord-023443-pvz7dll9	285	3	bacterial	bacterial	JJ
cord-023443-pvz7dll9	285	4	antigen	antigen	NN
cord-023443-pvz7dll9	285	5	-	-	HYPH
cord-023443-pvz7dll9	285	6	induced	induce	VBN
cord-023443-pvz7dll9	285	7	release	release	NN
cord-023443-pvz7dll9	285	8	of	of	IN
cord-023443-pvz7dll9	285	9	sVEGF	sVEGF	NNP
cord-023443-pvz7dll9	285	10	and	and	CC
cord-023443-pvz7dll9	285	11	neutrophile	neutrophile	JJ
cord-023443-pvz7dll9	285	12	cell	cell	NN
cord-023443-pvz7dll9	285	13	count	count	NN
cord-023443-pvz7dll9	285	14	was	be	VBD
cord-023443-pvz7dll9	285	15	highly	highly	RB
cord-023443-pvz7dll9	285	16	significant	significant	JJ
cord-023443-pvz7dll9	285	17	(	(	-LRB-
cord-023443-pvz7dll9	285	18	P	p	NN
cord-023443-pvz7dll9	285	19	<	<	XX
cord-023443-pvz7dll9	285	20	0.0001	0.0001	CD
cord-023443-pvz7dll9	285	21	)	)	-RRB-
cord-023443-pvz7dll9	285	22	.	.	.
cord-023443-pvz7dll9	286	1	There	there	EX
cord-023443-pvz7dll9	286	2	was	be	VBD
cord-023443-pvz7dll9	286	3	no	no	DT
cord-023443-pvz7dll9	286	4	correlation	correlation	NN
cord-023443-pvz7dll9	286	5	between	between	IN
cord-023443-pvz7dll9	286	6	sVEGF	svegf	NN
cord-023443-pvz7dll9	286	7	and	and	CC
cord-023443-pvz7dll9	286	8	platelet	platelet	NN
cord-023443-pvz7dll9	286	9	cell	cell	NN
cord-023443-pvz7dll9	286	10	count	count	NN
cord-023443-pvz7dll9	286	11	,	,	,
cord-023443-pvz7dll9	286	12	and	and	CC
cord-023443-pvz7dll9	286	13	bacterial	bacterial	JJ
cord-023443-pvz7dll9	286	14	antigen	antigen	NN
cord-023443-pvz7dll9	286	15	-	-	HYPH
cord-023443-pvz7dll9	286	16	induced	induce	VBN
cord-023443-pvz7dll9	286	17	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	286	18	release	release	NN
cord-023443-pvz7dll9	286	19	did	do	VBD
cord-023443-pvz7dll9	286	20	not	not	RB
cord-023443-pvz7dll9	286	21	correlate	correlate	VB
cord-023443-pvz7dll9	286	22	with	with	IN
cord-023443-pvz7dll9	286	23	counts	count	NNS
cord-023443-pvz7dll9	286	24	of	of	IN
cord-023443-pvz7dll9	286	25	neutrophils	neutrophil	NNS
cord-023443-pvz7dll9	286	26	and	and	CC
cord-023443-pvz7dll9	286	27	platelets	platelet	NNS
cord-023443-pvz7dll9	286	28	.	.	.
cord-023443-pvz7dll9	287	1	Conclusions	conclusion	NNS
cord-023443-pvz7dll9	287	2	:	:	:
cord-023443-pvz7dll9	288	1	Plasma	plasma	NN
cord-023443-pvz7dll9	288	2	sVEGF	svegf	NN
cord-023443-pvz7dll9	288	3	and	and	CC
cord-023443-pvz7dll9	288	4	sVEGFR1	svegfr1	NN
cord-023443-pvz7dll9	288	5	concentrations	concentration	NNS
cord-023443-pvz7dll9	288	6	did	do	VBD
cord-023443-pvz7dll9	288	7	not	not	RB
cord-023443-pvz7dll9	288	8	change	change	VB
cord-023443-pvz7dll9	288	9	during	during	IN
cord-023443-pvz7dll9	288	10	surgery	surgery	NN
cord-023443-pvz7dll9	288	11	.	.	.
cord-023443-pvz7dll9	289	1	In	in	IN
cord-023443-pvz7dll9	289	2	vitro	vitro	FW
cord-023443-pvz7dll9	289	3	bacterial	bacterial	JJ
cord-023443-pvz7dll9	289	4	stimulation	stimulation	NN
cord-023443-pvz7dll9	289	5	led	lead	VBD
cord-023443-pvz7dll9	289	6	to	to	IN
cord-023443-pvz7dll9	289	7	increased	increase	VBN
cord-023443-pvz7dll9	289	8	release	release	NN
cord-023443-pvz7dll9	289	9	of	of	IN
cord-023443-pvz7dll9	289	10	sVEGF	sVEGF	NNP
cord-023443-pvz7dll9	289	11	and	and	CC
cord-023443-pvz7dll9	289	12	sVEGFR1	sVEGFR1	NNP
cord-023443-pvz7dll9	289	13	,	,	,
cord-023443-pvz7dll9	289	14	which	which	WDT
cord-023443-pvz7dll9	289	15	was	be	VBD
cord-023443-pvz7dll9	289	16	not	not	RB
cord-023443-pvz7dll9	289	17	significantly	significantly	RB
cord-023443-pvz7dll9	289	18	amplified	amplify	VBN
cord-023443-pvz7dll9	289	19	during	during	IN
cord-023443-pvz7dll9	289	20	surgery	surgery	NN
cord-023443-pvz7dll9	289	21	and	and	CC
cord-023443-pvz7dll9	289	22	which	which	WDT
cord-023443-pvz7dll9	289	23	may	may	MD
cord-023443-pvz7dll9	289	24	be	be	VB
cord-023443-pvz7dll9	289	25	related	relate	VBN
cord-023443-pvz7dll9	289	26	to	to	IN
cord-023443-pvz7dll9	289	27	number	number	NN
cord-023443-pvz7dll9	289	28	of	of	IN
cord-023443-pvz7dll9	289	29	circulating	circulate	VBG
cord-023443-pvz7dll9	289	30	neutrophils	neutrophil	NNS
cord-023443-pvz7dll9	289	31	.	.	.
cord-023443-pvz7dll9	290	1	Natural	natural	JJ
cord-023443-pvz7dll9	290	2	Killer	Killer	NNP
cord-023443-pvz7dll9	290	3	Cell	Cell	NNP
cord-023443-pvz7dll9	290	4	Functions	Functions	NNPS
cord-023443-pvz7dll9	290	5	and	and	CC
cord-023443-pvz7dll9	290	6	Subsets	subset	NNS
cord-023443-pvz7dll9	291	1	After	after	IN
cord-023443-pvz7dll9	291	2	In	in	IN
cord-023443-pvz7dll9	291	3	Vitro	vitro	JJ
cord-023443-pvz7dll9	291	4	Stimulation	stimulation	NN
cord-023443-pvz7dll9	291	5	with	with	IN
cord-023443-pvz7dll9	291	6	IL-2	IL-2	NNP
cord-023443-pvz7dll9	291	7	and	and	CC
cord-023443-pvz7dll9	291	8	IL-12	IL-12	NNP
cord-023443-pvz7dll9	291	9	,	,	,
cord-023443-pvz7dll9	291	10	with	with	IN
cord-023443-pvz7dll9	291	11	Special	Special	NNP
cord-023443-pvz7dll9	291	12	Emphasis	Emphasis	NNP
cord-023443-pvz7dll9	291	13	on	on	IN
cord-023443-pvz7dll9	291	14	Intracellular	Intracellular	NNP
cord-023443-pvz7dll9	291	15	IFN	IFN	NNP
cord-023443-pvz7dll9	291	16	-	-	HYPH
cord-023443-pvz7dll9	291	17	g	g	NNP
cord-023443-pvz7dll9	291	18	and	and	CC
cord-023443-pvz7dll9	292	1	NK	NK	NNP
cord-023443-pvz7dll9	292	2	-	-	HYPH
cord-023443-pvz7dll9	292	3	Cell	Cell	NNP
cord-023443-pvz7dll9	292	4	Cytotoxicity	Cytotoxicity	NNP
cord-023443-pvz7dll9	292	5	R.	R.	NNP
cord-023443-pvz7dll9	292	6	Nyboe	Nyboe	NNP
cord-023443-pvz7dll9	292	7	,	,	,
cord-023443-pvz7dll9	292	8	1,2	1,2	CD
cord-023443-pvz7dll9	292	9	T.	T.	NNP
cord-023443-pvz7dll9	292	10	Rix	Rix	NNP
cord-023443-pvz7dll9	292	11	,	,	,
cord-023443-pvz7dll9	292	12	1,2	1,2	CD
cord-023443-pvz7dll9	292	13	J.	J.	NNP
cord-023443-pvz7dll9	292	14	Krog	Krog	NNP
cord-023443-pvz7dll9	292	15	,	,	,
cord-023443-pvz7dll9	292	16	1,2	1,2	CD
cord-023443-pvz7dll9	292	17	E.	E.	NNP
cord-023443-pvz7dll9	292	18	Tønnesen	Tønnesen	NNP
cord-023443-pvz7dll9	292	19	1	1	CD
cord-023443-pvz7dll9	292	20	&	&	CC
cord-023443-pvz7dll9	292	21	M.	M.	NNP
cord-023443-pvz7dll9	292	22	Hokland	Hokland	NNP
cord-023443-pvz7dll9	292	23	2	2	CD
cord-023443-pvz7dll9	292	24	1	1	CD
cord-023443-pvz7dll9	292	25	Department	Department	NNP
cord-023443-pvz7dll9	292	26	of	of	IN
cord-023443-pvz7dll9	292	27	Anaesthesiology	Anaesthesiology	NNP
cord-023443-pvz7dll9	292	28	and	and	CC
cord-023443-pvz7dll9	292	29	Intensive	Intensive	NNP
cord-023443-pvz7dll9	292	30	Care	Care	NNP
cord-023443-pvz7dll9	292	31	,	,	,
cord-023443-pvz7dll9	292	32	Aarhus	Aarhus	NNP
cord-023443-pvz7dll9	292	33	University	University	NNP
cord-023443-pvz7dll9	292	34	hospital	hospital	NN
cord-023443-pvz7dll9	292	35	,	,	,
cord-023443-pvz7dll9	292	36	and	and	CC
cord-023443-pvz7dll9	292	37	2	2	CD
cord-023443-pvz7dll9	292	38	Institute	Institute	NNP
cord-023443-pvz7dll9	292	39	of	of	IN
cord-023443-pvz7dll9	292	40	Medical	Medical	NNP
cord-023443-pvz7dll9	292	41	Microbiology	Microbiology	NNP
cord-023443-pvz7dll9	292	42	,	,	,
cord-023443-pvz7dll9	292	43	and	and	CC
cord-023443-pvz7dll9	292	44	Immunology	Immunology	NNP
cord-023443-pvz7dll9	292	45	,	,	,
cord-023443-pvz7dll9	292	46	University	University	NNP
cord-023443-pvz7dll9	292	47	of	of	IN
cord-023443-pvz7dll9	292	48	Aarhus	Aarhus	NNP
cord-023443-pvz7dll9	292	49	,	,	,
cord-023443-pvz7dll9	292	50	Aarhus	Aarhus	NNP
cord-023443-pvz7dll9	292	51	,	,	,
cord-023443-pvz7dll9	292	52	Denmark	Denmark	NNP
cord-023443-pvz7dll9	292	53	.	.	.
cord-023443-pvz7dll9	293	1	E	e	NN
cord-023443-pvz7dll9	293	2	-	-	NN
cord-023443-pvz7dll9	293	3	mail	mail	NN
cord-023443-pvz7dll9	293	4	:	:	:
cord-023443-pvz7dll9	294	1	rnsr@studmed.au.dk	rnsr@studmed.au.dk	NFP
cord-023443-pvz7dll9	294	2	Materials	material	NNS
cord-023443-pvz7dll9	294	3	and	and	CC
cord-023443-pvz7dll9	294	4	methods	method	NNS
cord-023443-pvz7dll9	294	5	:	:	:
cord-023443-pvz7dll9	294	6	Isolated	isolated	JJ
cord-023443-pvz7dll9	294	7	cryopreserved	cryopreserved	JJ
cord-023443-pvz7dll9	294	8	human	human	JJ
cord-023443-pvz7dll9	294	9	peripheral	peripheral	JJ
cord-023443-pvz7dll9	294	10	blood	blood	NN
cord-023443-pvz7dll9	294	11	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	294	12	cells	cell	NNS
cord-023443-pvz7dll9	294	13	(	(	-LRB-
cord-023443-pvz7dll9	294	14	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	294	15	)	)	-RRB-
cord-023443-pvz7dll9	294	16	were	be	VBD
cord-023443-pvz7dll9	294	17	stimulated	stimulate	VBN
cord-023443-pvz7dll9	294	18	with	with	IN
cord-023443-pvz7dll9	294	19	IL-2	IL-2	NNP
cord-023443-pvz7dll9	294	20	and	and	CC
cord-023443-pvz7dll9	294	21	IL-12	IL-12	NNP
cord-023443-pvz7dll9	294	22	.	.	.
cord-023443-pvz7dll9	295	1	This	this	DT
cord-023443-pvz7dll9	295	2	stimulation	stimulation	NN
cord-023443-pvz7dll9	295	3	has	have	VBZ
cord-023443-pvz7dll9	295	4	previously	previously	RB
cord-023443-pvz7dll9	295	5	been	be	VBN
cord-023443-pvz7dll9	295	6	shown	show	VBN
cord-023443-pvz7dll9	295	7	to	to	TO
cord-023443-pvz7dll9	295	8	activate	activate	VB
cord-023443-pvz7dll9	295	9	NK	NK	NNP
cord-023443-pvz7dll9	295	10	cells	cell	NNS
cord-023443-pvz7dll9	295	11	.	.	.
cord-023443-pvz7dll9	296	1	Cell	cell	NN
cord-023443-pvz7dll9	296	2	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	296	3	was	be	VBD
cord-023443-pvz7dll9	296	4	measured	measure	VBN
cord-023443-pvz7dll9	296	5	by	by	IN
cord-023443-pvz7dll9	296	6	flow	flow	NN
cord-023443-pvz7dll9	296	7	cytometry	cytometry	NN
cord-023443-pvz7dll9	296	8	after	after	IN
cord-023443-pvz7dll9	296	9	incubation	incubation	NN
cord-023443-pvz7dll9	296	10	with	with	IN
cord-023443-pvz7dll9	296	11	k562	k562	NN
cord-023443-pvz7dll9	296	12	cells	cell	NNS
cord-023443-pvz7dll9	296	13	.	.	.
cord-023443-pvz7dll9	297	1	This	this	DT
cord-023443-pvz7dll9	297	2	method	method	NN
cord-023443-pvz7dll9	297	3	was	be	VBD
cord-023443-pvz7dll9	297	4	compared	compare	VBN
cord-023443-pvz7dll9	297	5	to	to	IN
cord-023443-pvz7dll9	297	6	the	the	DT
cord-023443-pvz7dll9	297	7	current	current	JJ
cord-023443-pvz7dll9	297	8	standard	standard	JJ
cord-023443-pvz7dll9	297	9	51Cr	51cr	CD
cord-023443-pvz7dll9	297	10	release	release	NN
cord-023443-pvz7dll9	297	11	assay	assay	NN
cord-023443-pvz7dll9	297	12	.	.	.
cord-023443-pvz7dll9	298	1	Cells	cell	NNS
cord-023443-pvz7dll9	298	2	were	be	VBD
cord-023443-pvz7dll9	298	3	treated	treat	VBN
cord-023443-pvz7dll9	298	4	with	with	IN
cord-023443-pvz7dll9	298	5	BFA	BFA	NNP
cord-023443-pvz7dll9	298	6	to	to	TO
cord-023443-pvz7dll9	298	7	accumulate	accumulate	VB
cord-023443-pvz7dll9	298	8	IFN	IFN	NNP
cord-023443-pvz7dll9	298	9	-	-	HYPH
cord-023443-pvz7dll9	298	10	g	g	NNP
cord-023443-pvz7dll9	298	11	,	,	,
cord-023443-pvz7dll9	298	12	stained	stain	VBN
cord-023443-pvz7dll9	298	13	for	for	IN
cord-023443-pvz7dll9	298	14	surface	surface	NN
cord-023443-pvz7dll9	298	15	markers	marker	NNS
cord-023443-pvz7dll9	298	16	,	,	,
cord-023443-pvz7dll9	298	17	permeabilized	permeabilized	JJ
cord-023443-pvz7dll9	298	18	and	and	CC
cord-023443-pvz7dll9	298	19	stained	stain	VBN
cord-023443-pvz7dll9	298	20	for	for	IN
cord-023443-pvz7dll9	298	21	intracellular	intracellular	JJ
cord-023443-pvz7dll9	298	22	IFN	IFN	NNP
cord-023443-pvz7dll9	298	23	-	-	HYPH
cord-023443-pvz7dll9	298	24	g	g	NNP
cord-023443-pvz7dll9	298	25	.	.	.
cord-023443-pvz7dll9	299	1	Flow	flow	NN
cord-023443-pvz7dll9	299	2	cytometry	cytometry	NN
cord-023443-pvz7dll9	299	3	was	be	VBD
cord-023443-pvz7dll9	299	4	then	then	RB
cord-023443-pvz7dll9	299	5	performed	perform	VBN
cord-023443-pvz7dll9	299	6	to	to	TO
cord-023443-pvz7dll9	299	7	measure	measure	VB
cord-023443-pvz7dll9	299	8	intracellular	intracellular	JJ
cord-023443-pvz7dll9	299	9	IFN	IFN	NNP
cord-023443-pvz7dll9	299	10	-	-	HYPH
cord-023443-pvz7dll9	299	11	g	g	NN
cord-023443-pvz7dll9	299	12	production	production	NN
cord-023443-pvz7dll9	299	13	in	in	IN
cord-023443-pvz7dll9	299	14	PBMC	PBMC	NNP
cord-023443-pvz7dll9	299	15	,	,	,
cord-023443-pvz7dll9	299	16	especially	especially	RB
cord-023443-pvz7dll9	299	17	in	in	IN
cord-023443-pvz7dll9	299	18	NK	NK	NNP
cord-023443-pvz7dll9	299	19	cells	cell	NNS
cord-023443-pvz7dll9	299	20	.	.	.
cord-023443-pvz7dll9	300	1	Results	result	NNS
cord-023443-pvz7dll9	300	2	:	:	:
cord-023443-pvz7dll9	301	1	We	-PRON-	PRP
cord-023443-pvz7dll9	301	2	have	have	VBP
cord-023443-pvz7dll9	301	3	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	301	4	that	that	IN
cord-023443-pvz7dll9	301	5	stimulation	stimulation	NN
cord-023443-pvz7dll9	301	6	with	with	IN
cord-023443-pvz7dll9	301	7	IL-2	IL-2	NNP
cord-023443-pvz7dll9	301	8	and	and	CC
cord-023443-pvz7dll9	301	9	IL-12	IL-12	NNP
cord-023443-pvz7dll9	301	10	is	be	VBZ
cord-023443-pvz7dll9	301	11	effective	effective	JJ
cord-023443-pvz7dll9	301	12	in	in	IN
cord-023443-pvz7dll9	301	13	increasing	increase	VBG
cord-023443-pvz7dll9	301	14	the	the	DT
cord-023443-pvz7dll9	301	15	number	number	NN
cord-023443-pvz7dll9	301	16	of	of	IN
cord-023443-pvz7dll9	301	17	IFN	IFN	NNP
cord-023443-pvz7dll9	301	18	-	-	HYPH
cord-023443-pvz7dll9	301	19	gpositive	gpositive	NN
cord-023443-pvz7dll9	301	20	cells	cell	NNS
cord-023443-pvz7dll9	301	21	.	.	.
cord-023443-pvz7dll9	302	1	There	there	EX
cord-023443-pvz7dll9	302	2	is	be	VBZ
cord-023443-pvz7dll9	302	3	a	a	DT
cord-023443-pvz7dll9	302	4	distinct	distinct	JJ
cord-023443-pvz7dll9	302	5	difference	difference	NN
cord-023443-pvz7dll9	302	6	between	between	IN
cord-023443-pvz7dll9	302	7	the	the	DT
cord-023443-pvz7dll9	302	8	CD3-CD56dim	CD3-CD56dim	NNP
cord-023443-pvz7dll9	302	9	and	and	CC
cord-023443-pvz7dll9	302	10	the	the	DT
cord-023443-pvz7dll9	302	11	CD3-CD56bright	cd3-cd56bright	NN
cord-023443-pvz7dll9	302	12	subsets	subset	NNS
cord-023443-pvz7dll9	302	13	,	,	,
cord-023443-pvz7dll9	302	14	with	with	IN
cord-023443-pvz7dll9	302	15	a	a	DT
cord-023443-pvz7dll9	302	16	much	much	RB
cord-023443-pvz7dll9	302	17	greater	great	JJR
cord-023443-pvz7dll9	302	18	proportion	proportion	NN
cord-023443-pvz7dll9	302	19	of	of	IN
cord-023443-pvz7dll9	302	20	IFN	IFN	NNP
cord-023443-pvz7dll9	302	21	-	-	HYPH
cord-023443-pvz7dll9	302	22	g	g	NN
cord-023443-pvz7dll9	302	23	-	-	HYPH
cord-023443-pvz7dll9	302	24	positive	positive	JJ
cord-023443-pvz7dll9	302	25	cells	cell	NNS
cord-023443-pvz7dll9	302	26	in	in	IN
cord-023443-pvz7dll9	302	27	the	the	DT
cord-023443-pvz7dll9	302	28	CD3-CD56bright	cd3-cd56bright	NN
cord-023443-pvz7dll9	302	29	subset	subset	JJ
cord-023443-pvz7dll9	302	30	.	.	.
cord-023443-pvz7dll9	303	1	The	the	DT
cord-023443-pvz7dll9	303	2	effects	effect	NNS
cord-023443-pvz7dll9	303	3	of	of	IN
cord-023443-pvz7dll9	303	4	stimulation	stimulation	NN
cord-023443-pvz7dll9	303	5	with	with	IN
cord-023443-pvz7dll9	303	6	IL-2	IL-2	NNP
cord-023443-pvz7dll9	303	7	and	and	CC
cord-023443-pvz7dll9	303	8	IL-12	IL-12	NNP
cord-023443-pvz7dll9	303	9	on	on	IN
cord-023443-pvz7dll9	303	10	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	303	11	will	will	MD
cord-023443-pvz7dll9	303	12	be	be	VB
cord-023443-pvz7dll9	303	13	presented	present	VBN
cord-023443-pvz7dll9	303	14	,	,	,
cord-023443-pvz7dll9	303	15	as	as	IN
cord-023443-pvz7dll9	303	16	will	will	MD
cord-023443-pvz7dll9	303	17	the	the	DT
cord-023443-pvz7dll9	303	18	relation	relation	NN
cord-023443-pvz7dll9	303	19	between	between	IN
cord-023443-pvz7dll9	303	20	IFN	IFN	NNP
cord-023443-pvz7dll9	303	21	-	-	HYPH
cord-023443-pvz7dll9	303	22	g	g	NN
cord-023443-pvz7dll9	303	23	production	production	NN
cord-023443-pvz7dll9	303	24	and	and	CC
cord-023443-pvz7dll9	303	25	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	303	26	.	.	.
cord-023443-pvz7dll9	304	1	In	in	IN
cord-023443-pvz7dll9	304	2	addition	addition	NN
cord-023443-pvz7dll9	304	3	,	,	,
cord-023443-pvz7dll9	304	4	we	-PRON-	PRP
cord-023443-pvz7dll9	304	5	will	will	MD
cord-023443-pvz7dll9	304	6	present	present	VB
cord-023443-pvz7dll9	304	7	results	result	NNS
cord-023443-pvz7dll9	304	8	of	of	IN
cord-023443-pvz7dll9	304	9	these	these	DT
cord-023443-pvz7dll9	304	10	assays	assay	NNS
cord-023443-pvz7dll9	304	11	applied	apply	VBN
cord-023443-pvz7dll9	304	12	to	to	IN
cord-023443-pvz7dll9	304	13	porcine	porcine	JJ
cord-023443-pvz7dll9	304	14	cells	cell	NNS
cord-023443-pvz7dll9	304	15	.	.	.
cord-023443-pvz7dll9	305	1	Discussion	discussion	NN
cord-023443-pvz7dll9	305	2	:	:	:
cord-023443-pvz7dll9	306	1	In	in	IN
cord-023443-pvz7dll9	306	2	combination	combination	NN
cord-023443-pvz7dll9	306	3	,	,	,
cord-023443-pvz7dll9	306	4	these	these	DT
cord-023443-pvz7dll9	306	5	tests	test	NNS
cord-023443-pvz7dll9	306	6	will	will	MD
cord-023443-pvz7dll9	306	7	address	address	VB
cord-023443-pvz7dll9	306	8	NK	NK	NNP
cord-023443-pvz7dll9	306	9	cell	cell	NN
cord-023443-pvz7dll9	306	10	function	function	NN
cord-023443-pvz7dll9	306	11	by	by	IN
cord-023443-pvz7dll9	306	12	combining	combine	VBG
cord-023443-pvz7dll9	306	13	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	306	14	with	with	IN
cord-023443-pvz7dll9	306	15	IFN	IFN	NNP
cord-023443-pvz7dll9	306	16	-	-	HYPH
cord-023443-pvz7dll9	306	17	g	g	NN
cord-023443-pvz7dll9	306	18	production	production	NN
cord-023443-pvz7dll9	306	19	in	in	IN
cord-023443-pvz7dll9	306	20	NK	NK	NNP
cord-023443-pvz7dll9	306	21	cell	cell	NN
cord-023443-pvz7dll9	306	22	subsets	subset	NNS
cord-023443-pvz7dll9	306	23	.	.	.
cord-023443-pvz7dll9	307	1	The	the	DT
cord-023443-pvz7dll9	307	2	results	result	NNS
cord-023443-pvz7dll9	307	3	will	will	MD
cord-023443-pvz7dll9	307	4	demonstrate	demonstrate	VB
cord-023443-pvz7dll9	307	5	whether	whether	IN
cord-023443-pvz7dll9	307	6	this	this	DT
cord-023443-pvz7dll9	307	7	could	could	MD
cord-023443-pvz7dll9	307	8	serve	serve	VB
cord-023443-pvz7dll9	307	9	as	as	IN
cord-023443-pvz7dll9	307	10	a	a	DT
cord-023443-pvz7dll9	307	11	useful	useful	JJ
cord-023443-pvz7dll9	307	12	tool	tool	NN
cord-023443-pvz7dll9	307	13	in	in	IN
cord-023443-pvz7dll9	307	14	describing	describe	VBG
cord-023443-pvz7dll9	307	15	NKcell	NKcell	NNP
cord-023443-pvz7dll9	307	16	function	function	NN
cord-023443-pvz7dll9	307	17	,	,	,
cord-023443-pvz7dll9	307	18	which	which	WDT
cord-023443-pvz7dll9	307	19	could	could	MD
cord-023443-pvz7dll9	307	20	be	be	VB
cord-023443-pvz7dll9	307	21	of	of	IN
cord-023443-pvz7dll9	307	22	value	value	NN
cord-023443-pvz7dll9	307	23	in	in	IN
cord-023443-pvz7dll9	307	24	clinical	clinical	JJ
cord-023443-pvz7dll9	307	25	and	and	CC
cord-023443-pvz7dll9	307	26	experimental	experimental	JJ
cord-023443-pvz7dll9	307	27	settings	setting	NNS
cord-023443-pvz7dll9	307	28	.	.	.
cord-023443-pvz7dll9	308	1	Culture	culture	NN
cord-023443-pvz7dll9	308	2	of	of	IN
cord-023443-pvz7dll9	308	3	Regulatory	Regulatory	NNP
cord-023443-pvz7dll9	308	4	T	T	NNP
cord-023443-pvz7dll9	308	5	-	-	HYPH
cord-023443-pvz7dll9	308	6	Cell	cell	NN
cord-023443-pvz7dll9	308	7	Lines	line	NNS
cord-023443-pvz7dll9	308	8	from	from	IN
cord-023443-pvz7dll9	308	9	Bronchial	Bronchial	NNP
cord-023443-pvz7dll9	308	10	Mucosa	Mucosa	NNP
cord-023443-pvz7dll9	308	11	T	T	NNP
cord-023443-pvz7dll9	308	12	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	308	13	play	play	VBP
cord-023443-pvz7dll9	308	14	a	a	DT
cord-023443-pvz7dll9	308	15	major	major	JJ
cord-023443-pvz7dll9	308	16	role	role	NN
cord-023443-pvz7dll9	308	17	in	in	IN
cord-023443-pvz7dll9	308	18	many	many	JJ
cord-023443-pvz7dll9	308	19	immune	immune	JJ
cord-023443-pvz7dll9	308	20	responses	response	NNS
cord-023443-pvz7dll9	308	21	.	.	.
cord-023443-pvz7dll9	309	1	In	in	IN
cord-023443-pvz7dll9	309	2	the	the	DT
cord-023443-pvz7dll9	309	3	last	last	JJ
cord-023443-pvz7dll9	309	4	decade	decade	NN
cord-023443-pvz7dll9	309	5	,	,	,
cord-023443-pvz7dll9	309	6	special	special	JJ
cord-023443-pvz7dll9	309	7	focus	focus	NN
cord-023443-pvz7dll9	309	8	has	have	VBZ
cord-023443-pvz7dll9	309	9	been	be	VBN
cord-023443-pvz7dll9	309	10	on	on	IN
cord-023443-pvz7dll9	309	11	the	the	DT
cord-023443-pvz7dll9	309	12	function	function	NN
cord-023443-pvz7dll9	309	13	of	of	IN
cord-023443-pvz7dll9	309	14	Th1	th1	NN
cord-023443-pvz7dll9	309	15	and	and	CC
cord-023443-pvz7dll9	309	16	Th2	th2	CD
cord-023443-pvz7dll9	309	17	effector	effector	NN
cord-023443-pvz7dll9	309	18	cells	cell	NNS
cord-023443-pvz7dll9	309	19	.	.	.
cord-023443-pvz7dll9	310	1	Now	now	RB
cord-023443-pvz7dll9	310	2	the	the	DT
cord-023443-pvz7dll9	310	3	importance	importance	NN
cord-023443-pvz7dll9	310	4	of	of	IN
cord-023443-pvz7dll9	310	5	regulatory	regulatory	JJ
cord-023443-pvz7dll9	310	6	CD4	CD4	NNP
cord-023443-pvz7dll9	310	7	þ	þ	NNP
cord-023443-pvz7dll9	310	8	CD25	CD25	NNP
cord-023443-pvz7dll9	310	9	þ	þ	NNP
cord-023443-pvz7dll9	310	10	T	t	NN
cord-023443-pvz7dll9	310	11	cells	cell	NNS
cord-023443-pvz7dll9	310	12	in	in	IN
cord-023443-pvz7dll9	310	13	maintenance	maintenance	NN
cord-023443-pvz7dll9	310	14	of	of	IN
cord-023443-pvz7dll9	310	15	the	the	DT
cord-023443-pvz7dll9	310	16	immunological	immunological	JJ
cord-023443-pvz7dll9	310	17	homeostasis	homeostasis	NN
cord-023443-pvz7dll9	310	18	emerges	emerge	VBZ
cord-023443-pvz7dll9	310	19	.	.	.
cord-023443-pvz7dll9	311	1	Sarcoidosis	sarcoidosis	NN
cord-023443-pvz7dll9	311	2	is	be	VBZ
cord-023443-pvz7dll9	311	3	a	a	DT
cord-023443-pvz7dll9	311	4	multisystem	multisystem	JJ
cord-023443-pvz7dll9	311	5	granulomatous	granulomatous	JJ
cord-023443-pvz7dll9	311	6	disorder	disorder	NN
cord-023443-pvz7dll9	311	7	often	often	RB
cord-023443-pvz7dll9	311	8	affecting	affect	VBG
cord-023443-pvz7dll9	311	9	the	the	DT
cord-023443-pvz7dll9	311	10	lungs	lung	NNS
cord-023443-pvz7dll9	311	11	.	.	.
cord-023443-pvz7dll9	312	1	The	the	DT
cord-023443-pvz7dll9	312	2	typical	typical	JJ
cord-023443-pvz7dll9	312	3	sarcoid	sarcoid	NN
cord-023443-pvz7dll9	312	4	granulomas	granuloma	NNS
cord-023443-pvz7dll9	312	5	consists	consist	VBZ
cord-023443-pvz7dll9	312	6	of	of	IN
cord-023443-pvz7dll9	312	7	epitheloid	epitheloid	NNP
cord-023443-pvz7dll9	312	8	cells	cell	NNS
cord-023443-pvz7dll9	312	9	,	,	,
cord-023443-pvz7dll9	312	10	macrophages	macrophage	NNS
cord-023443-pvz7dll9	312	11	and	and	CC
cord-023443-pvz7dll9	312	12	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	312	13	,	,	,
cord-023443-pvz7dll9	312	14	mainly	mainly	RB
cord-023443-pvz7dll9	312	15	CD4	CD4	NNP
cord-023443-pvz7dll9	312	16	þ	þ	NNP
cord-023443-pvz7dll9	312	17	T	T	NNP
cord-023443-pvz7dll9	312	18	cells	cell	NNS
cord-023443-pvz7dll9	312	19	of	of	IN
cord-023443-pvz7dll9	312	20	Th1	th1	CD
cord-023443-pvz7dll9	312	21	phenotype	phenotype	NN
cord-023443-pvz7dll9	312	22	.	.	.
cord-023443-pvz7dll9	313	1	We	-PRON-	PRP
cord-023443-pvz7dll9	313	2	have	have	VBP
cord-023443-pvz7dll9	313	3	cultured	culture	VBN
cord-023443-pvz7dll9	313	4	T	t	NN
cord-023443-pvz7dll9	313	5	cells	cell	NNS
cord-023443-pvz7dll9	313	6	from	from	IN
cord-023443-pvz7dll9	313	7	bronchial	bronchial	JJ
cord-023443-pvz7dll9	313	8	biopsies	biopsy	NNS
cord-023443-pvz7dll9	313	9	of	of	IN
cord-023443-pvz7dll9	313	10	patients	patient	NNS
cord-023443-pvz7dll9	313	11	with	with	IN
cord-023443-pvz7dll9	313	12	sarcoidosis	sarcoidosi	NNS
cord-023443-pvz7dll9	313	13	as	as	RB
cord-023443-pvz7dll9	313	14	well	well	RB
cord-023443-pvz7dll9	313	15	as	as	IN
cord-023443-pvz7dll9	313	16	from	from	IN
cord-023443-pvz7dll9	313	17	controls	control	NNS
cord-023443-pvz7dll9	313	18	in	in	IN
cord-023443-pvz7dll9	313	19	high	high	JJ
cord-023443-pvz7dll9	313	20	levels	level	NNS
cord-023443-pvz7dll9	313	21	of	of	IN
cord-023443-pvz7dll9	313	22	interleukin	interleukin	NN
cord-023443-pvz7dll9	313	23	2	2	CD
cord-023443-pvz7dll9	313	24	(	(	-LRB-
cord-023443-pvz7dll9	313	25	IL-2	IL-2	NNP
cord-023443-pvz7dll9	313	26	)	)	-RRB-
cord-023443-pvz7dll9	313	27	and	and	CC
cord-023443-pvz7dll9	313	28	IL-4	IL-4	NNP
cord-023443-pvz7dll9	313	29	and	and	CC
cord-023443-pvz7dll9	313	30	demonstrate	demonstrate	VB
cord-023443-pvz7dll9	313	31	spontaneously	spontaneously	RB
cord-023443-pvz7dll9	313	32	arising	arise	VBG
cord-023443-pvz7dll9	313	33	CD4	CD4	NNP
cord-023443-pvz7dll9	313	34	þ	þ	NNP
cord-023443-pvz7dll9	313	35	CD25	CD25	NNP
cord-023443-pvz7dll9	313	36	þ	þ	NNP
cord-023443-pvz7dll9	313	37	populations	population	NNS
cord-023443-pvz7dll9	313	38	and	and	CC
cord-023443-pvz7dll9	313	39	high	high	JJ
cord-023443-pvz7dll9	313	40	concentrations	concentration	NNS
cord-023443-pvz7dll9	313	41	of	of	IN
cord-023443-pvz7dll9	313	42	IL-10	IL-10	NNP
cord-023443-pvz7dll9	313	43	in	in	IN
cord-023443-pvz7dll9	313	44	these	these	DT
cord-023443-pvz7dll9	313	45	cultures	culture	NNS
cord-023443-pvz7dll9	313	46	.	.	.
cord-023443-pvz7dll9	314	1	The	the	DT
cord-023443-pvz7dll9	314	2	main	main	JJ
cord-023443-pvz7dll9	314	3	difference	difference	NN
cord-023443-pvz7dll9	314	4	between	between	IN
cord-023443-pvz7dll9	314	5	cultures	culture	NNS
cord-023443-pvz7dll9	314	6	of	of	IN
cord-023443-pvz7dll9	314	7	sarcoid	sarcoid	NNP
cord-023443-pvz7dll9	314	8	origin	origin	NN
cord-023443-pvz7dll9	314	9	compared	compare	VBN
cord-023443-pvz7dll9	314	10	to	to	IN
cord-023443-pvz7dll9	314	11	controls	control	NNS
cord-023443-pvz7dll9	314	12	is	be	VBZ
cord-023443-pvz7dll9	314	13	a	a	DT
cord-023443-pvz7dll9	314	14	very	very	RB
cord-023443-pvz7dll9	314	15	much	much	RB
cord-023443-pvz7dll9	314	16	higher	high	JJR
cord-023443-pvz7dll9	314	17	concentration	concentration	NN
cord-023443-pvz7dll9	314	18	of	of	IN
cord-023443-pvz7dll9	314	19	the	the	DT
cord-023443-pvz7dll9	314	20	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	314	21	cytokines	cytokine	NNS
cord-023443-pvz7dll9	314	22	IL-6	IL-6	NNP
cord-023443-pvz7dll9	314	23	and	and	CC
cord-023443-pvz7dll9	314	24	TNF	TNF	NNP
cord-023443-pvz7dll9	314	25	-	-	,
cord-023443-pvz7dll9	314	26	a	a	NN
cord-023443-pvz7dll9	314	27	in	in	IN
cord-023443-pvz7dll9	314	28	cultures	culture	NNS
cord-023443-pvz7dll9	314	29	of	of	IN
cord-023443-pvz7dll9	314	30	sarcoid	sarcoid	NNP
cord-023443-pvz7dll9	314	31	origin	origin	NN
cord-023443-pvz7dll9	314	32	.	.	.
cord-023443-pvz7dll9	315	1	The	the	DT
cord-023443-pvz7dll9	315	2	Effects	effect	NNS
cord-023443-pvz7dll9	315	3	of	of	IN
cord-023443-pvz7dll9	315	4	Hyperbaric	Hyperbaric	NNP
cord-023443-pvz7dll9	315	5	Exposure	Exposure	NNP
cord-023443-pvz7dll9	315	6	on	on	IN
cord-023443-pvz7dll9	315	7	Human	Human	NNP
cord-023443-pvz7dll9	315	8	Peripheral	Peripheral	NNP
cord-023443-pvz7dll9	315	9	Blood	Blood	NNP
cord-023443-pvz7dll9	315	10	Mononuclear	Mononuclear	NNP
cord-023443-pvz7dll9	315	11	Cells	Cells	NNPS
cord-023443-pvz7dll9	315	12	,	,	,
cord-023443-pvz7dll9	315	13	with	with	IN
cord-023443-pvz7dll9	315	14	Special	Special	NNP
cord-023443-pvz7dll9	315	15	Emphasis	Emphasis	NNP
cord-023443-pvz7dll9	315	16	on	on	IN
cord-023443-pvz7dll9	315	17	Natural	Natural	NNP
cord-023443-pvz7dll9	315	18	Killer	Killer	NNP
cord-023443-pvz7dll9	315	19	Cell	Cell	NNP
cord-023443-pvz7dll9	315	20	Cytotoxicity	Cytotoxicity	NNP
cord-023443-pvz7dll9	315	21	and	and	CC
cord-023443-pvz7dll9	315	22	Subsets	Subsets	NNPS
cord-023443-pvz7dll9	315	23	Materials	material	NNS
cord-023443-pvz7dll9	315	24	and	and	CC
cord-023443-pvz7dll9	315	25	methods	method	NNS
cord-023443-pvz7dll9	315	26	:	:	:
cord-023443-pvz7dll9	316	1	As	as	IN
cord-023443-pvz7dll9	316	2	an	an	DT
cord-023443-pvz7dll9	316	3	experimental	experimental	JJ
cord-023443-pvz7dll9	316	4	physiological	physiological	JJ
cord-023443-pvz7dll9	316	5	stress	stress	NN
cord-023443-pvz7dll9	316	6	model	model	NN
cord-023443-pvz7dll9	316	7	,	,	,
cord-023443-pvz7dll9	316	8	we	-PRON-	PRP
cord-023443-pvz7dll9	316	9	examined	examine	VBD
cord-023443-pvz7dll9	316	10	the	the	DT
cord-023443-pvz7dll9	316	11	effects	effect	NNS
cord-023443-pvz7dll9	316	12	of	of	IN
cord-023443-pvz7dll9	316	13	hyperbaric	hyperbaric	NN
cord-023443-pvz7dll9	316	14	exposure	exposure	NN
cord-023443-pvz7dll9	316	15	on	on	IN
cord-023443-pvz7dll9	316	16	peripheral	peripheral	JJ
cord-023443-pvz7dll9	316	17	blood	blood	NN
cord-023443-pvz7dll9	316	18	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	316	19	cells	cell	NNS
cord-023443-pvz7dll9	316	20	(	(	-LRB-
cord-023443-pvz7dll9	316	21	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	316	22	)	)	-RRB-
cord-023443-pvz7dll9	316	23	obtained	obtain	VBN
cord-023443-pvz7dll9	316	24	from	from	IN
cord-023443-pvz7dll9	316	25	venous	venous	JJ
cord-023443-pvz7dll9	316	26	blood	blood	NN
cord-023443-pvz7dll9	316	27	drawn	draw	VBN
cord-023443-pvz7dll9	316	28	from	from	IN
cord-023443-pvz7dll9	316	29	eight	eight	CD
cord-023443-pvz7dll9	316	30	divers	diver	NNS
cord-023443-pvz7dll9	316	31	during	during	IN
cord-023443-pvz7dll9	316	32	a	a	DT
cord-023443-pvz7dll9	316	33	simulated	simulate	VBN
cord-023443-pvz7dll9	316	34	heliox	heliox	NN
cord-023443-pvz7dll9	316	35	saturation	saturation	NN
cord-023443-pvz7dll9	316	36	dive	dive	NN
cord-023443-pvz7dll9	316	37	.	.	.
cord-023443-pvz7dll9	317	1	Eight	eight	CD
cord-023443-pvz7dll9	317	2	persons	person	NNS
cord-023443-pvz7dll9	317	3	working	work	VBG
cord-023443-pvz7dll9	317	4	in	in	IN
cord-023443-pvz7dll9	317	5	normobar	normobar	NNP
cord-023443-pvz7dll9	317	6	atmosphere	atmosphere	NN
cord-023443-pvz7dll9	317	7	outside	outside	IN
cord-023443-pvz7dll9	317	8	the	the	DT
cord-023443-pvz7dll9	317	9	pressurized	pressurize	VBN
cord-023443-pvz7dll9	317	10	chamber	chamber	NN
cord-023443-pvz7dll9	317	11	served	serve	VBD
cord-023443-pvz7dll9	317	12	as	as	IN
cord-023443-pvz7dll9	317	13	control	control	NN
cord-023443-pvz7dll9	317	14	donors	donor	NNS
cord-023443-pvz7dll9	317	15	.	.	.
cord-023443-pvz7dll9	318	1	The	the	DT
cord-023443-pvz7dll9	318	2	spontaneous	spontaneous	JJ
cord-023443-pvz7dll9	318	3	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	318	4	of	of	IN
cord-023443-pvz7dll9	318	5	the	the	DT
cord-023443-pvz7dll9	318	6	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	318	7	was	be	VBD
cord-023443-pvz7dll9	318	8	estimated	estimate	VBN
cord-023443-pvz7dll9	318	9	in	in	IN
cord-023443-pvz7dll9	318	10	a	a	DT
cord-023443-pvz7dll9	318	11	4	4	CD
cord-023443-pvz7dll9	318	12	h	h	NN
cord-023443-pvz7dll9	318	13	51Cr	51cr	CD
cord-023443-pvz7dll9	318	14	-	-	HYPH
cord-023443-pvz7dll9	318	15	release	release	NN
cord-023443-pvz7dll9	318	16	assay	assay	NN
cord-023443-pvz7dll9	318	17	using	use	VBG
cord-023443-pvz7dll9	318	18	k562	k562	NNP
cord-023443-pvz7dll9	318	19	as	as	IN
cord-023443-pvz7dll9	318	20	NK	nk	NN
cord-023443-pvz7dll9	318	21	-	-	HYPH
cord-023443-pvz7dll9	318	22	sensitive	sensitive	JJ
cord-023443-pvz7dll9	318	23	target	target	NN
cord-023443-pvz7dll9	318	24	cells	cell	NNS
cord-023443-pvz7dll9	318	25	.	.	.
cord-023443-pvz7dll9	319	1	The	the	DT
cord-023443-pvz7dll9	319	2	PBMCs	pbmc	NNS
cord-023443-pvz7dll9	319	3	were	be	VBD
cord-023443-pvz7dll9	319	4	characterized	characterize	VBN
cord-023443-pvz7dll9	319	5	,	,	,
cord-023443-pvz7dll9	319	6	using	use	VBG
cord-023443-pvz7dll9	319	7	4-colour	4-colour	CD
cord-023443-pvz7dll9	319	8	flow	flow	NN
cord-023443-pvz7dll9	319	9	cytometry	cytometry	NN
cord-023443-pvz7dll9	319	10	,	,	,
cord-023443-pvz7dll9	319	11	with	with	IN
cord-023443-pvz7dll9	319	12	special	special	JJ
cord-023443-pvz7dll9	319	13	emphasis	emphasis	NN
cord-023443-pvz7dll9	319	14	on	on	IN
cord-023443-pvz7dll9	319	15	the	the	DT
cord-023443-pvz7dll9	319	16	NK	nk	NN
cord-023443-pvz7dll9	319	17	-	-	HYPH
cord-023443-pvz7dll9	319	18	cell	cell	NN
cord-023443-pvz7dll9	319	19	subsets	subset	NNS
cord-023443-pvz7dll9	319	20	.	.	.
cord-023443-pvz7dll9	320	1	The	the	DT
cord-023443-pvz7dll9	320	2	data	datum	NNS
cord-023443-pvz7dll9	320	3	were	be	VBD
cord-023443-pvz7dll9	320	4	statistically	statistically	RB
cord-023443-pvz7dll9	320	5	analysed	analyse	VBN
cord-023443-pvz7dll9	320	6	using	use	VBG
cord-023443-pvz7dll9	320	7	a	a	DT
cord-023443-pvz7dll9	320	8	multivariate	multivariate	JJ
cord-023443-pvz7dll9	320	9	regression	regression	NN
cord-023443-pvz7dll9	320	10	model	model	NN
cord-023443-pvz7dll9	320	11	(	(	-LRB-
cord-023443-pvz7dll9	320	12	Stata	Stata	NNP
cord-023443-pvz7dll9	320	13	8.2	8.2	CD
cord-023443-pvz7dll9	320	14	)	)	-RRB-
cord-023443-pvz7dll9	320	15	.	.	.
cord-023443-pvz7dll9	321	1	P	p	NN
cord-023443-pvz7dll9	321	2	values	value	NNS
cord-023443-pvz7dll9	321	3	<	<	XX
cord-023443-pvz7dll9	321	4	0.05	0.05	CD
cord-023443-pvz7dll9	321	5	was	be	VBD
cord-023443-pvz7dll9	321	6	considered	consider	VBN
cord-023443-pvz7dll9	321	7	statistically	statistically	RB
cord-023443-pvz7dll9	321	8	significant	significant	JJ
cord-023443-pvz7dll9	321	9	.	.	.
cord-023443-pvz7dll9	322	1	Results	result	NNS
cord-023443-pvz7dll9	322	2	:	:	:
cord-023443-pvz7dll9	323	1	The	the	DT
cord-023443-pvz7dll9	323	2	estimated	estimate	VBN
cord-023443-pvz7dll9	323	3	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	323	4	increased	increase	VBD
cord-023443-pvz7dll9	323	5	significantly	significantly	RB
cord-023443-pvz7dll9	323	6	in	in	IN
cord-023443-pvz7dll9	323	7	both	both	CC
cord-023443-pvz7dll9	323	8	the	the	DT
cord-023443-pvz7dll9	323	9	group	group	NN
cord-023443-pvz7dll9	323	10	of	of	IN
cord-023443-pvz7dll9	323	11	divers	diver	NNS
cord-023443-pvz7dll9	323	12	and	and	CC
cord-023443-pvz7dll9	323	13	control	control	VB
cord-023443-pvz7dll9	323	14	donors	donor	NNS
cord-023443-pvz7dll9	323	15	during	during	IN
cord-023443-pvz7dll9	323	16	the	the	DT
cord-023443-pvz7dll9	323	17	dive	dive	NN
cord-023443-pvz7dll9	323	18	(	(	-LRB-
cord-023443-pvz7dll9	323	19	pdivers	pdivers	NNP
cord-023443-pvz7dll9	323	20	<	<	XX
cord-023443-pvz7dll9	323	21	0.01	0.01	CD
cord-023443-pvz7dll9	323	22	and	and	CC
cord-023443-pvz7dll9	323	23	pcontrols	pcontrols	NNP
cord-023443-pvz7dll9	323	24	<	<	XX
cord-023443-pvz7dll9	323	25	0.01	0.01	CD
cord-023443-pvz7dll9	323	26	)	)	-RRB-
cord-023443-pvz7dll9	323	27	.	.	.
cord-023443-pvz7dll9	324	1	Although	although	IN
cord-023443-pvz7dll9	324	2	the	the	DT
cord-023443-pvz7dll9	324	3	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	324	4	increased	increase	VBD
cord-023443-pvz7dll9	324	5	relatively	relatively	RB
cord-023443-pvz7dll9	324	6	more	more	RBR
cord-023443-pvz7dll9	324	7	(	(	-LRB-
cord-023443-pvz7dll9	324	8	P	p	NN
cord-023443-pvz7dll9	324	9	<	<	XX
cord-023443-pvz7dll9	324	10	0.01	0.01	CD
cord-023443-pvz7dll9	324	11	)	)	-RRB-
cord-023443-pvz7dll9	324	12	in	in	IN
cord-023443-pvz7dll9	324	13	the	the	DT
cord-023443-pvz7dll9	324	14	group	group	NN
cord-023443-pvz7dll9	324	15	of	of	IN
cord-023443-pvz7dll9	324	16	divers	diver	NNS
cord-023443-pvz7dll9	324	17	compared	compare	VBN
cord-023443-pvz7dll9	324	18	to	to	IN
cord-023443-pvz7dll9	324	19	the	the	DT
cord-023443-pvz7dll9	324	20	group	group	NN
cord-023443-pvz7dll9	324	21	of	of	IN
cord-023443-pvz7dll9	324	22	control	control	NN
cord-023443-pvz7dll9	324	23	donors	donor	NNS
cord-023443-pvz7dll9	324	24	between	between	IN
cord-023443-pvz7dll9	324	25	day	day	NN
cord-023443-pvz7dll9	324	26	1	1	CD
cord-023443-pvz7dll9	324	27	and	and	CC
cord-023443-pvz7dll9	324	28	2	2	CD
cord-023443-pvz7dll9	324	29	.	.	.
cord-023443-pvz7dll9	325	1	Discussion	discussion	NN
cord-023443-pvz7dll9	325	2	:	:	:
cord-023443-pvz7dll9	326	1	The	the	DT
cord-023443-pvz7dll9	326	2	increased	increase	VBN
cord-023443-pvz7dll9	326	3	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	326	4	of	of	IN
cord-023443-pvz7dll9	326	5	PBMC	PBMC	NNP
cord-023443-pvz7dll9	326	6	estimated	estimate	VBN
cord-023443-pvz7dll9	326	7	in	in	IN
cord-023443-pvz7dll9	326	8	the	the	DT
cord-023443-pvz7dll9	326	9	group	group	NN
cord-023443-pvz7dll9	326	10	of	of	IN
cord-023443-pvz7dll9	326	11	divers	diver	NNS
cord-023443-pvz7dll9	326	12	indicate	indicate	VBP
cord-023443-pvz7dll9	326	13	that	that	IN
cord-023443-pvz7dll9	326	14	parts	part	NNS
cord-023443-pvz7dll9	326	15	of	of	IN
cord-023443-pvz7dll9	326	16	the	the	DT
cord-023443-pvz7dll9	326	17	cellular	cellular	JJ
cord-023443-pvz7dll9	326	18	immune	immune	JJ
cord-023443-pvz7dll9	326	19	system	system	NN
cord-023443-pvz7dll9	326	20	are	be	VBP
cord-023443-pvz7dll9	326	21	affected	affect	VBN
cord-023443-pvz7dll9	326	22	during	during	IN
cord-023443-pvz7dll9	326	23	the	the	DT
cord-023443-pvz7dll9	326	24	extreme	extreme	JJ
cord-023443-pvz7dll9	326	25	physiological	physiological	JJ
cord-023443-pvz7dll9	326	26	conditions	condition	NNS
cord-023443-pvz7dll9	326	27	induced	induce	VBN
cord-023443-pvz7dll9	326	28	during	during	IN
cord-023443-pvz7dll9	326	29	the	the	DT
cord-023443-pvz7dll9	326	30	initial	initial	JJ
cord-023443-pvz7dll9	326	31	phase	phase	NN
cord-023443-pvz7dll9	326	32	of	of	IN
cord-023443-pvz7dll9	326	33	the	the	DT
cord-023443-pvz7dll9	326	34	presented	present	VBN
cord-023443-pvz7dll9	326	35	experimental	experimental	JJ
cord-023443-pvz7dll9	326	36	hyperbaric	hyperbaric	NN
cord-023443-pvz7dll9	326	37	setup	setup	NN
cord-023443-pvz7dll9	326	38	.	.	.
cord-023443-pvz7dll9	327	1	The	the	DT
cord-023443-pvz7dll9	327	2	increase	increase	NN
cord-023443-pvz7dll9	327	3	in	in	IN
cord-023443-pvz7dll9	327	4	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	327	5	observed	observe	VBN
cord-023443-pvz7dll9	327	6	in	in	IN
cord-023443-pvz7dll9	327	7	the	the	DT
cord-023443-pvz7dll9	327	8	group	group	NN
cord-023443-pvz7dll9	327	9	of	of	IN
cord-023443-pvz7dll9	327	10	control	control	NN
cord-023443-pvz7dll9	327	11	donors	donor	NNS
cord-023443-pvz7dll9	327	12	could	could	MD
cord-023443-pvz7dll9	327	13	hypothetically	hypothetically	RB
cord-023443-pvz7dll9	327	14	reflect	reflect	VB
cord-023443-pvz7dll9	327	15	the	the	DT
cord-023443-pvz7dll9	327	16	stress	stress	NN
cord-023443-pvz7dll9	327	17	level	level	NN
cord-023443-pvz7dll9	327	18	in	in	IN
cord-023443-pvz7dll9	327	19	persons	person	NNS
cord-023443-pvz7dll9	327	20	working	work	VBG
cord-023443-pvz7dll9	327	21	outside	outside	IN
cord-023443-pvz7dll9	327	22	the	the	DT
cord-023443-pvz7dll9	327	23	pressurized	pressurize	VBN
cord-023443-pvz7dll9	327	24	chamber	chamber	NN
cord-023443-pvz7dll9	327	25	during	during	IN
cord-023443-pvz7dll9	327	26	the	the	DT
cord-023443-pvz7dll9	327	27	dive	dive	NN
cord-023443-pvz7dll9	327	28	.	.	.
cord-023443-pvz7dll9	328	1	The	the	DT
cord-023443-pvz7dll9	328	2	interaction	interaction	NN
cord-023443-pvz7dll9	328	3	with	with	IN
cord-023443-pvz7dll9	328	4	adhesion	adhesion	NN
cord-023443-pvz7dll9	328	5	molecules	molecule	NNS
cord-023443-pvz7dll9	328	6	expressed	express	VBN
cord-023443-pvz7dll9	328	7	by	by	IN
cord-023443-pvz7dll9	328	8	vascular	vascular	JJ
cord-023443-pvz7dll9	328	9	endothelium	endothelium	NN
cord-023443-pvz7dll9	328	10	is	be	VBZ
cord-023443-pvz7dll9	328	11	the	the	DT
cord-023443-pvz7dll9	328	12	first	first	JJ
cord-023443-pvz7dll9	328	13	step	step	NN
cord-023443-pvz7dll9	328	14	in	in	IN
cord-023443-pvz7dll9	328	15	lymphocyte	lymphocyte	NN
cord-023443-pvz7dll9	328	16	infiltration	infiltration	NN
cord-023443-pvz7dll9	328	17	into	into	IN
cord-023443-pvz7dll9	328	18	tissues	tissue	NNS
cord-023443-pvz7dll9	328	19	.	.	.
cord-023443-pvz7dll9	329	1	At	at	IN
cord-023443-pvz7dll9	329	2	both	both	CC
cord-023443-pvz7dll9	329	3	cutaneous	cutaneous	JJ
cord-023443-pvz7dll9	329	4	and	and	CC
cord-023443-pvz7dll9	329	5	mucosal	mucosal	JJ
cord-023443-pvz7dll9	329	6	sites	site	NNS
cord-023443-pvz7dll9	329	7	interleukin-10	interleukin-10	NN
cord-023443-pvz7dll9	329	8	(	(	-LRB-
cord-023443-pvz7dll9	329	9	IL-10	IL-10	NNP
cord-023443-pvz7dll9	329	10	)	)	-RRB-
cord-023443-pvz7dll9	329	11	,	,	,
cord-023443-pvz7dll9	329	12	IL-12	IL-12	NNP
cord-023443-pvz7dll9	329	13	and	and	CC
cord-023443-pvz7dll9	329	14	transforming	transform	VBG
cord-023443-pvz7dll9	329	15	growth	growth	NN
cord-023443-pvz7dll9	329	16	factor	factor	NN
cord-023443-pvz7dll9	329	17	(	(	-LRB-
cord-023443-pvz7dll9	329	18	TGF)-b	TGF)-b	NNS
cord-023443-pvz7dll9	329	19	are	be	VBP
cord-023443-pvz7dll9	329	20	important	important	JJ
cord-023443-pvz7dll9	329	21	regulators	regulator	NNS
cord-023443-pvz7dll9	329	22	of	of	IN
cord-023443-pvz7dll9	329	23	chronic	chronic	JJ
cord-023443-pvz7dll9	329	24	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	329	25	disease	disease	NN
cord-023443-pvz7dll9	329	26	,	,	,
cord-023443-pvz7dll9	329	27	where	where	WRB
cord-023443-pvz7dll9	329	28	cutaneous	cutaneous	JJ
cord-023443-pvz7dll9	329	29	lymphocyteassociated	lymphocyteassociated	JJ
cord-023443-pvz7dll9	329	30	antigen	antigen	NN
cord-023443-pvz7dll9	329	31	(	(	-LRB-
cord-023443-pvz7dll9	329	32	CLA	CLA	NNP
cord-023443-pvz7dll9	329	33	)	)	-RRB-
cord-023443-pvz7dll9	329	34	and	and	CC
cord-023443-pvz7dll9	329	35	aE	ae	NN
cord-023443-pvz7dll9	329	36	integrin	integrin	NNP
cord-023443-pvz7dll9	329	37	(	(	-LRB-
cord-023443-pvz7dll9	329	38	CD103	CD103	NNP
cord-023443-pvz7dll9	329	39	)	)	-RRB-
cord-023443-pvz7dll9	329	40	may	may	MD
cord-023443-pvz7dll9	329	41	be	be	VB
cord-023443-pvz7dll9	329	42	expressed	express	VBN
cord-023443-pvz7dll9	329	43	.	.	.
cord-023443-pvz7dll9	330	1	Unlike	unlike	IN
cord-023443-pvz7dll9	330	2	CLA	CLA	NNP
cord-023443-pvz7dll9	330	3	,	,	,
cord-023443-pvz7dll9	330	4	CD103	CD103	NNP
cord-023443-pvz7dll9	330	5	is	be	VBZ
cord-023443-pvz7dll9	330	6	not	not	RB
cord-023443-pvz7dll9	330	7	believed	believe	VBN
cord-023443-pvz7dll9	330	8	to	to	TO
cord-023443-pvz7dll9	330	9	play	play	VB
cord-023443-pvz7dll9	330	10	a	a	DT
cord-023443-pvz7dll9	330	11	role	role	NN
cord-023443-pvz7dll9	330	12	in	in	IN
cord-023443-pvz7dll9	330	13	tissue	tissue	NN
cord-023443-pvz7dll9	330	14	-	-	HYPH
cord-023443-pvz7dll9	330	15	specific	specific	JJ
cord-023443-pvz7dll9	330	16	homing	homing	NN
cord-023443-pvz7dll9	330	17	but	but	CC
cord-023443-pvz7dll9	330	18	may	may	MD
cord-023443-pvz7dll9	330	19	help	help	VB
cord-023443-pvz7dll9	330	20	to	to	TO
cord-023443-pvz7dll9	330	21	retain	retain	VB
cord-023443-pvz7dll9	330	22	T	t	NN
cord-023443-pvz7dll9	330	23	cells	cell	NNS
cord-023443-pvz7dll9	330	24	within	within	IN
cord-023443-pvz7dll9	330	25	epithelial	epithelial	JJ
cord-023443-pvz7dll9	330	26	layers	layer	NNS
cord-023443-pvz7dll9	330	27	.	.	.
cord-023443-pvz7dll9	331	1	We	-PRON-	PRP
cord-023443-pvz7dll9	331	2	have	have	VBP
cord-023443-pvz7dll9	331	3	previously	previously	RB
cord-023443-pvz7dll9	331	4	shown	show	VBN
cord-023443-pvz7dll9	331	5	that	that	IN
cord-023443-pvz7dll9	331	6	IL-12	IL-12	NNP
cord-023443-pvz7dll9	331	7	alone	alone	RB
cord-023443-pvz7dll9	331	8	can	can	MD
cord-023443-pvz7dll9	331	9	together	together	RB
cord-023443-pvz7dll9	331	10	with	with	IN
cord-023443-pvz7dll9	331	11	an	an	DT
cord-023443-pvz7dll9	331	12	unknown	unknown	JJ
cord-023443-pvz7dll9	331	13	cofactor	cofactor	NN
cord-023443-pvz7dll9	331	14	increase	increase	NN
cord-023443-pvz7dll9	331	15	the	the	DT
cord-023443-pvz7dll9	331	16	expression	expression	NN
cord-023443-pvz7dll9	331	17	of	of	IN
cord-023443-pvz7dll9	331	18	CLA	CLA	NNP
cord-023443-pvz7dll9	331	19	.	.	.
cord-023443-pvz7dll9	332	1	Stimulation	stimulation	NN
cord-023443-pvz7dll9	332	2	with	with	IN
cord-023443-pvz7dll9	332	3	streptococcal	streptococcal	JJ
cord-023443-pvz7dll9	332	4	pyrogenic	pyrogenic	JJ
cord-023443-pvz7dll9	332	5	exotoxin	exotoxin	NN
cord-023443-pvz7dll9	332	6	C	C	NNP
cord-023443-pvz7dll9	332	7	(	(	-LRB-
cord-023443-pvz7dll9	332	8	SpeC	spec	NN
cord-023443-pvz7dll9	332	9	)	)	-RRB-
cord-023443-pvz7dll9	332	10	increased	increase	VBD
cord-023443-pvz7dll9	332	11	the	the	DT
cord-023443-pvz7dll9	332	12	expression	expression	NN
cord-023443-pvz7dll9	332	13	of	of	IN
cord-023443-pvz7dll9	332	14	CD103	CD103	NNP
cord-023443-pvz7dll9	332	15	by	by	IN
cord-023443-pvz7dll9	332	16	CD8	CD8	NNP
cord-023443-pvz7dll9	332	17	þ	þ	NNP
cord-023443-pvz7dll9	332	18	but	but	CC
cord-023443-pvz7dll9	332	19	not	not	RB
cord-023443-pvz7dll9	332	20	CD4	CD4	NNP
cord-023443-pvz7dll9	332	21	þ	þ	NNP
cord-023443-pvz7dll9	332	22	T	t	NN
cord-023443-pvz7dll9	332	23	cells	cell	NNS
cord-023443-pvz7dll9	332	24	.	.	.
cord-023443-pvz7dll9	333	1	While	while	IN
cord-023443-pvz7dll9	333	2	IL-12	IL-12	NNP
cord-023443-pvz7dll9	333	3	increased	increase	VBD
cord-023443-pvz7dll9	333	4	superantigen	superantigen	NN
cord-023443-pvz7dll9	333	5	-	-	HYPH
cord-023443-pvz7dll9	333	6	stimulated	stimulate	VBN
cord-023443-pvz7dll9	333	7	expression	expression	NN
cord-023443-pvz7dll9	333	8	of	of	IN
cord-023443-pvz7dll9	333	9	CLA	CLA	NNP
cord-023443-pvz7dll9	333	10	,	,	,
cord-023443-pvz7dll9	333	11	this	this	DT
cord-023443-pvz7dll9	333	12	cytokine	cytokine	NN
cord-023443-pvz7dll9	333	13	strongly	strongly	RB
cord-023443-pvz7dll9	333	14	inhibited	inhibit	VBD
cord-023443-pvz7dll9	333	15	the	the	DT
cord-023443-pvz7dll9	333	16	CD103	CD103	NNP
cord-023443-pvz7dll9	333	17	expres	expres	NNP
cord-023443-pvz7dll9	333	18	-	-	HYPH
cord-023443-pvz7dll9	333	19	sion	sion	NNP
cord-023443-pvz7dll9	333	20	,	,	,
cord-023443-pvz7dll9	333	21	and	and	CC
cord-023443-pvz7dll9	333	22	a	a	DT
cord-023443-pvz7dll9	333	23	combination	combination	NN
cord-023443-pvz7dll9	333	24	of	of	IN
cord-023443-pvz7dll9	333	25	IL-12	IL-12	NNP
cord-023443-pvz7dll9	333	26	and	and	CC
cord-023443-pvz7dll9	333	27	TGF	TGF	NNP
cord-023443-pvz7dll9	333	28	-	-	HYPH
cord-023443-pvz7dll9	333	29	b	b	LS
cord-023443-pvz7dll9	333	30	completely	completely	RB
cord-023443-pvz7dll9	333	31	abrogated	abrogate	VBD
cord-023443-pvz7dll9	333	32	the	the	DT
cord-023443-pvz7dll9	333	33	induced	induce	VBN
cord-023443-pvz7dll9	333	34	CD103	cd103	NN
cord-023443-pvz7dll9	333	35	expression	expression	NN
cord-023443-pvz7dll9	333	36	.	.	.
cord-023443-pvz7dll9	334	1	Conversely	conversely	RB
cord-023443-pvz7dll9	334	2	,	,	,
cord-023443-pvz7dll9	334	3	IL-10	IL-10	NNP
cord-023443-pvz7dll9	334	4	suppressed	suppress	VBD
cord-023443-pvz7dll9	334	5	CLA	CLA	NNP
cord-023443-pvz7dll9	334	6	but	but	CC
cord-023443-pvz7dll9	334	7	increased	increase	VBD
cord-023443-pvz7dll9	334	8	CD103	CD103	NNP
cord-023443-pvz7dll9	334	9	expression	expression	NN
cord-023443-pvz7dll9	334	10	.	.	.
cord-023443-pvz7dll9	335	1	These	these	DT
cord-023443-pvz7dll9	335	2	findings	finding	NNS
cord-023443-pvz7dll9	335	3	indicate	indicate	VBP
cord-023443-pvz7dll9	335	4	that	that	IN
cord-023443-pvz7dll9	335	5	,	,	,
cord-023443-pvz7dll9	335	6	in	in	IN
cord-023443-pvz7dll9	335	7	addition	addition	NN
cord-023443-pvz7dll9	335	8	to	to	IN
cord-023443-pvz7dll9	335	9	suppressing	suppress	VBG
cord-023443-pvz7dll9	335	10	the	the	DT
cord-023443-pvz7dll9	335	11	development	development	NN
cord-023443-pvz7dll9	335	12	of	of	IN
cord-023443-pvz7dll9	335	13	Th1-mediated	Th1-mediated	NNP
cord-023443-pvz7dll9	335	14	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	335	15	responses	response	NNS
cord-023443-pvz7dll9	335	16	,	,	,
cord-023443-pvz7dll9	335	17	IL-10	IL-10	NNP
cord-023443-pvz7dll9	335	18	may	may	MD
cord-023443-pvz7dll9	335	19	also	also	RB
cord-023443-pvz7dll9	335	20	inhibit	inhibit	VB
cord-023443-pvz7dll9	335	21	the	the	DT
cord-023443-pvz7dll9	335	22	migration	migration	NN
cord-023443-pvz7dll9	335	23	of	of	IN
cord-023443-pvz7dll9	335	24	CD8	CD8	NNP
cord-023443-pvz7dll9	335	25	þ	þ	NNP
cord-023443-pvz7dll9	335	26	T	T	NNP
cord-023443-pvz7dll9	335	27	cells	cell	NNS
cord-023443-pvz7dll9	335	28	into	into	IN
cord-023443-pvz7dll9	335	29	the	the	DT
cord-023443-pvz7dll9	335	30	skin	skin	NN
cord-023443-pvz7dll9	335	31	while	while	IN
cord-023443-pvz7dll9	335	32	IL-12	IL-12	NNP
cord-023443-pvz7dll9	335	33	promotes	promote	VBZ
cord-023443-pvz7dll9	335	34	such	such	JJ
cord-023443-pvz7dll9	335	35	migration	migration	NN
cord-023443-pvz7dll9	335	36	.	.	.
cord-023443-pvz7dll9	336	1	Thus	thus	RB
cord-023443-pvz7dll9	336	2	,	,	,
cord-023443-pvz7dll9	336	3	the	the	DT
cord-023443-pvz7dll9	336	4	expression	expression	NN
cord-023443-pvz7dll9	336	5	of	of	IN
cord-023443-pvz7dll9	336	6	CLA	CLA	NNP
cord-023443-pvz7dll9	336	7	and	and	CC
cord-023443-pvz7dll9	336	8	CD103	CD103	NNP
cord-023443-pvz7dll9	336	9	may	may	MD
cord-023443-pvz7dll9	336	10	be	be	VB
cord-023443-pvz7dll9	336	11	antagonistically	antagonistically	RB
cord-023443-pvz7dll9	336	12	regulated	regulate	VBN
cord-023443-pvz7dll9	336	13	by	by	IN
cord-023443-pvz7dll9	336	14	IL-10	IL-10	NNP
cord-023443-pvz7dll9	336	15	and	and	CC
cord-023443-pvz7dll9	336	16	IL-12	IL-12	NNP
cord-023443-pvz7dll9	336	17	,	,	,
cord-023443-pvz7dll9	336	18	and	and	CC
cord-023443-pvz7dll9	336	19	the	the	DT
cord-023443-pvz7dll9	336	20	balance	balance	NN
cord-023443-pvz7dll9	336	21	between	between	IN
cord-023443-pvz7dll9	336	22	these	these	DT
cord-023443-pvz7dll9	336	23	cytokines	cytokine	NNS
cord-023443-pvz7dll9	336	24	could	could	MD
cord-023443-pvz7dll9	336	25	influence	influence	VB
cord-023443-pvz7dll9	336	26	the	the	DT
cord-023443-pvz7dll9	336	27	T	t	NN
cord-023443-pvz7dll9	336	28	-	-	HYPH
cord-023443-pvz7dll9	336	29	cell	cell	NN
cord-023443-pvz7dll9	336	30	migration	migration	NN
cord-023443-pvz7dll9	336	31	of	of	IN
cord-023443-pvz7dll9	336	32	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	336	33	cells	cell	NNS
cord-023443-pvz7dll9	336	34	into	into	IN
cord-023443-pvz7dll9	336	35	epithelial	epithelial	JJ
cord-023443-pvz7dll9	336	36	tissues	tissue	NNS
cord-023443-pvz7dll9	336	37	.	.	.
cord-023443-pvz7dll9	337	1	During	during	IN
cord-023443-pvz7dll9	337	2	contact	contact	NN
cord-023443-pvz7dll9	337	3	sensitivity	sensitivity	NN
cord-023443-pvz7dll9	337	4	reaction	reaction	NN
cord-023443-pvz7dll9	337	5	,	,	,
cord-023443-pvz7dll9	337	6	immune	immune	JJ
cord-023443-pvz7dll9	337	7	cells	cell	NNS
cord-023443-pvz7dll9	337	8	proliferate	proliferate	VBP
cord-023443-pvz7dll9	337	9	.	.	.
cord-023443-pvz7dll9	338	1	In	in	IN
cord-023443-pvz7dll9	338	2	order	order	NN
cord-023443-pvz7dll9	338	3	to	to	TO
cord-023443-pvz7dll9	338	4	study	study	VB
cord-023443-pvz7dll9	338	5	the	the	DT
cord-023443-pvz7dll9	338	6	histological	histological	JJ
cord-023443-pvz7dll9	338	7	picture	picture	NN
cord-023443-pvz7dll9	338	8	of	of	IN
cord-023443-pvz7dll9	338	9	these	these	DT
cord-023443-pvz7dll9	338	10	proliferation	proliferation	NN
cord-023443-pvz7dll9	338	11	phases	phase	NNS
cord-023443-pvz7dll9	338	12	,	,	,
cord-023443-pvz7dll9	338	13	we	-PRON-	PRP
cord-023443-pvz7dll9	338	14	used	use	VBD
cord-023443-pvz7dll9	338	15	a	a	DT
cord-023443-pvz7dll9	338	16	mouse	mouse	NN
cord-023443-pvz7dll9	338	17	model	model	NN
cord-023443-pvz7dll9	338	18	of	of	IN
cord-023443-pvz7dll9	338	19	contact	contact	NN
cord-023443-pvz7dll9	338	20	sensitivity	sensitivity	NN
cord-023443-pvz7dll9	338	21	in	in	IN
cord-023443-pvz7dll9	338	22	the	the	DT
cord-023443-pvz7dll9	338	23	oral	oral	JJ
cord-023443-pvz7dll9	338	24	mucosa	mucosa	NN
cord-023443-pvz7dll9	338	25	and	and	CC
cord-023443-pvz7dll9	338	26	on	on	IN
cord-023443-pvz7dll9	338	27	skin	skin	NN
cord-023443-pvz7dll9	338	28	.	.	.
cord-023443-pvz7dll9	339	1	We	-PRON-	PRP
cord-023443-pvz7dll9	339	2	also	also	RB
cord-023443-pvz7dll9	339	3	used	use	VBD
cord-023443-pvz7dll9	339	4	bromodeoxyuridin	bromodeoxyuridin	NNP
cord-023443-pvz7dll9	339	5	(	(	-LRB-
cord-023443-pvz7dll9	339	6	BrdU	BrdU	NNP
cord-023443-pvz7dll9	339	7	,	,	,
cord-023443-pvz7dll9	339	8	an	an	DT
cord-023443-pvz7dll9	339	9	analogue	analogue	NN
cord-023443-pvz7dll9	339	10	to	to	TO
cord-023443-pvz7dll9	339	11	thymidin	thymidin	VB
cord-023443-pvz7dll9	339	12	)	)	-RRB-
cord-023443-pvz7dll9	339	13	that	that	WDT
cord-023443-pvz7dll9	339	14	is	be	VBZ
cord-023443-pvz7dll9	339	15	incorporated	incorporate	VBN
cord-023443-pvz7dll9	339	16	into	into	IN
cord-023443-pvz7dll9	339	17	the	the	DT
cord-023443-pvz7dll9	339	18	nucleus	nucleus	NN
cord-023443-pvz7dll9	339	19	during	during	IN
cord-023443-pvz7dll9	339	20	cell	cell	NN
cord-023443-pvz7dll9	339	21	replication	replication	NN
cord-023443-pvz7dll9	339	22	.	.	.
cord-023443-pvz7dll9	340	1	The	the	DT
cord-023443-pvz7dll9	340	2	hapten	hapten	NNP
cord-023443-pvz7dll9	340	3	oxazolone	oxazolone	NN
cord-023443-pvz7dll9	340	4	(	(	-LRB-
cord-023443-pvz7dll9	340	5	OXA	OXA	NNP
cord-023443-pvz7dll9	340	6	)	)	-RRB-
cord-023443-pvz7dll9	340	7	was	be	VBD
cord-023443-pvz7dll9	340	8	used	use	VBN
cord-023443-pvz7dll9	340	9	to	to	TO
cord-023443-pvz7dll9	340	10	sensitize	sensitize	VB
cord-023443-pvz7dll9	340	11	and	and	CC
cord-023443-pvz7dll9	340	12	elicit	elicit	VB
cord-023443-pvz7dll9	340	13	the	the	DT
cord-023443-pvz7dll9	340	14	oral	oral	JJ
cord-023443-pvz7dll9	340	15	mucosa	mucosa	NN
cord-023443-pvz7dll9	340	16	and/or	and/or	CC
cord-023443-pvz7dll9	340	17	the	the	DT
cord-023443-pvz7dll9	340	18	ear	ear	NN
cord-023443-pvz7dll9	340	19	skin	skin	NN
cord-023443-pvz7dll9	340	20	.	.	.
cord-023443-pvz7dll9	341	1	Mice	mouse	NNS
cord-023443-pvz7dll9	341	2	were	be	VBD
cord-023443-pvz7dll9	341	3	killed	kill	VBN
cord-023443-pvz7dll9	341	4	at	at	IN
cord-023443-pvz7dll9	341	5	various	various	JJ
cord-023443-pvz7dll9	341	6	times	time	NNS
cord-023443-pvz7dll9	341	7	after	after	IN
cord-023443-pvz7dll9	341	8	elicitation	elicitation	NN
cord-023443-pvz7dll9	341	9	,	,	,
cord-023443-pvz7dll9	341	10	and	and	CC
cord-023443-pvz7dll9	341	11	unsensitized	unsensitized	JJ
cord-023443-pvz7dll9	341	12	animals	animal	NNS
cord-023443-pvz7dll9	341	13	were	be	VBD
cord-023443-pvz7dll9	341	14	also	also	RB
cord-023443-pvz7dll9	341	15	exposed	expose	VBN
cord-023443-pvz7dll9	341	16	to	to	IN
cord-023443-pvz7dll9	341	17	the	the	DT
cord-023443-pvz7dll9	341	18	hapten	hapten	NNP
cord-023443-pvz7dll9	341	19	as	as	IN
cord-023443-pvz7dll9	341	20	controls	control	NNS
cord-023443-pvz7dll9	341	21	.	.	.
cord-023443-pvz7dll9	342	1	BrdU	BrdU	NNP
cord-023443-pvz7dll9	342	2	(	(	-LRB-
cord-023443-pvz7dll9	342	3	25	25	CD
cord-023443-pvz7dll9	342	4	mg/	mg/	NN
cord-023443-pvz7dll9	342	5	kg	kg	NNP
cord-023443-pvz7dll9	342	6	animal	animal	NN
cord-023443-pvz7dll9	342	7	)	)	-RRB-
cord-023443-pvz7dll9	342	8	was	be	VBD
cord-023443-pvz7dll9	342	9	injected	inject	VBN
cord-023443-pvz7dll9	342	10	i.p	i.p	NNP
cord-023443-pvz7dll9	342	11	.	.	NNP
cord-023443-pvz7dll9	342	12	2	2	CD
cord-023443-pvz7dll9	342	13	h	h	NN
cord-023443-pvz7dll9	342	14	before	before	IN
cord-023443-pvz7dll9	342	15	the	the	DT
cord-023443-pvz7dll9	342	16	kill	kill	NN
cord-023443-pvz7dll9	342	17	.	.	.
cord-023443-pvz7dll9	343	1	Specimens	specimen	NNS
cord-023443-pvz7dll9	343	2	from	from	IN
cord-023443-pvz7dll9	343	3	the	the	DT
cord-023443-pvz7dll9	343	4	oral	oral	JJ
cord-023443-pvz7dll9	343	5	mucosa	mucosa	NN
cord-023443-pvz7dll9	343	6	,	,	,
cord-023443-pvz7dll9	343	7	ear	ear	NN
cord-023443-pvz7dll9	343	8	skin	skin	NN
cord-023443-pvz7dll9	343	9	and	and	CC
cord-023443-pvz7dll9	343	10	submandibular	submandibular	JJ
cord-023443-pvz7dll9	343	11	and	and	CC
cord-023443-pvz7dll9	343	12	auricular	auricular	JJ
cord-023443-pvz7dll9	343	13	lymph	lymph	NN
cord-023443-pvz7dll9	343	14	nodes	node	NNS
cord-023443-pvz7dll9	343	15	were	be	VBD
cord-023443-pvz7dll9	343	16	cut	cut	VBN
cord-023443-pvz7dll9	343	17	and	and	CC
cord-023443-pvz7dll9	343	18	fixed	fix	VBN
cord-023443-pvz7dll9	343	19	in	in	IN
cord-023443-pvz7dll9	343	20	4	4	CD
cord-023443-pvz7dll9	343	21	%	%	NN
cord-023443-pvz7dll9	343	22	paraformaldehyde	paraformaldehyde	NNP
cord-023443-pvz7dll9	343	23	.	.	.
cord-023443-pvz7dll9	344	1	They	-PRON-	PRP
cord-023443-pvz7dll9	344	2	were	be	VBD
cord-023443-pvz7dll9	344	3	then	then	RB
cord-023443-pvz7dll9	344	4	treated	treat	VBN
cord-023443-pvz7dll9	344	5	with	with	IN
cord-023443-pvz7dll9	344	6	acid	acid	NN
cord-023443-pvz7dll9	344	7	and	and	CC
cord-023443-pvz7dll9	344	8	biotinylated	biotinylated	JJ
cord-023443-pvz7dll9	344	9	anti	anti	NNP
cord-023443-pvz7dll9	344	10	-	-	NNP
cord-023443-pvz7dll9	344	11	BrdU	BrdU	NNP
cord-023443-pvz7dll9	344	12	antibody	antibody	NN
cord-023443-pvz7dll9	344	13	and	and	CC
cord-023443-pvz7dll9	344	14	developed	develop	VBD
cord-023443-pvz7dll9	344	15	using	use	VBG
cord-023443-pvz7dll9	344	16	ABC	ABC	NNP
cord-023443-pvz7dll9	344	17	-	-	HYPH
cord-023443-pvz7dll9	344	18	kit	kit	NN
cord-023443-pvz7dll9	344	19	and	and	CC
cord-023443-pvz7dll9	344	20	DAB	dab	NN
cord-023443-pvz7dll9	344	21	.	.	.
cord-023443-pvz7dll9	345	1	The	the	DT
cord-023443-pvz7dll9	345	2	analyses	analysis	NNS
cord-023443-pvz7dll9	345	3	were	be	VBD
cord-023443-pvz7dll9	345	4	performed	perform	VBN
cord-023443-pvz7dll9	345	5	using	use	VBG
cord-023443-pvz7dll9	345	6	a	a	DT
cord-023443-pvz7dll9	345	7	Leica	Leica	NNP
cord-023443-pvz7dll9	345	8	light	light	JJ
cord-023443-pvz7dll9	345	9	microscope	microscope	NN
cord-023443-pvz7dll9	345	10	and	and	CC
cord-023443-pvz7dll9	345	11	the	the	DT
cord-023443-pvz7dll9	345	12	computer	computer	NN
cord-023443-pvz7dll9	345	13	program	program	NN
cord-023443-pvz7dll9	345	14	ANALYSIS	analysis	NN
cord-023443-pvz7dll9	345	15	.	.	.
cord-023443-pvz7dll9	346	1	In	in	IN
cord-023443-pvz7dll9	346	2	the	the	DT
cord-023443-pvz7dll9	346	3	oral	oral	JJ
cord-023443-pvz7dll9	346	4	mucosa	mucosa	NN
cord-023443-pvz7dll9	346	5	,	,	,
cord-023443-pvz7dll9	346	6	the	the	DT
cord-023443-pvz7dll9	346	7	frequency	frequency	NN
cord-023443-pvz7dll9	346	8	of	of	IN
cord-023443-pvz7dll9	346	9	proliferating	proliferate	VBG
cord-023443-pvz7dll9	346	10	cells	cell	NNS
cord-023443-pvz7dll9	346	11	were	be	VBD
cord-023443-pvz7dll9	346	12	increasing	increase	VBG
cord-023443-pvz7dll9	346	13	during	during	IN
cord-023443-pvz7dll9	346	14	the	the	DT
cord-023443-pvz7dll9	346	15	observation	observation	NN
cord-023443-pvz7dll9	346	16	period	period	NN
cord-023443-pvz7dll9	346	17	,	,	,
cord-023443-pvz7dll9	346	18	4	4	CD
cord-023443-pvz7dll9	346	19	-	-	SYM
cord-023443-pvz7dll9	346	20	24	24	CD
cord-023443-pvz7dll9	346	21	h	h	NN
cord-023443-pvz7dll9	346	22	after	after	IN
cord-023443-pvz7dll9	346	23	elicitation	elicitation	NN
cord-023443-pvz7dll9	346	24	,	,	,
cord-023443-pvz7dll9	346	25	regardless	regardless	RB
cord-023443-pvz7dll9	346	26	of	of	IN
cord-023443-pvz7dll9	346	27	site	site	NN
cord-023443-pvz7dll9	346	28	of	of	IN
cord-023443-pvz7dll9	346	29	sensitization	sensitization	NN
cord-023443-pvz7dll9	346	30	.	.	.
cord-023443-pvz7dll9	347	1	The	the	DT
cord-023443-pvz7dll9	347	2	proliferating	proliferate	VBG
cord-023443-pvz7dll9	347	3	cells	cell	NNS
cord-023443-pvz7dll9	347	4	were	be	VBD
cord-023443-pvz7dll9	347	5	found	find	VBN
cord-023443-pvz7dll9	347	6	mainly	mainly	RB
cord-023443-pvz7dll9	347	7	in	in	IN
cord-023443-pvz7dll9	347	8	the	the	DT
cord-023443-pvz7dll9	347	9	basal	basal	NN
cord-023443-pvz7dll9	347	10	cell	cell	NN
cord-023443-pvz7dll9	347	11	layer	layer	NN
cord-023443-pvz7dll9	347	12	of	of	IN
cord-023443-pvz7dll9	347	13	the	the	DT
cord-023443-pvz7dll9	347	14	epithelium	epithelium	NN
cord-023443-pvz7dll9	347	15	.	.	.
cord-023443-pvz7dll9	348	1	Similar	similar	JJ
cord-023443-pvz7dll9	348	2	patterns	pattern	NNS
cord-023443-pvz7dll9	348	3	were	be	VBD
cord-023443-pvz7dll9	348	4	found	find	VBN
cord-023443-pvz7dll9	348	5	in	in	IN
cord-023443-pvz7dll9	348	6	ear	ear	NN
cord-023443-pvz7dll9	348	7	skin	skin	NN
cord-023443-pvz7dll9	348	8	.	.	.
cord-023443-pvz7dll9	349	1	The	the	DT
cord-023443-pvz7dll9	349	2	regional	regional	JJ
cord-023443-pvz7dll9	349	3	lymph	lymph	NN
cord-023443-pvz7dll9	349	4	nodes	node	NNS
cord-023443-pvz7dll9	349	5	demonstrated	demonstrate	VBD
cord-023443-pvz7dll9	349	6	a	a	DT
cord-023443-pvz7dll9	349	7	few	few	JJ
cord-023443-pvz7dll9	349	8	scattered	scatter	VBN
cord-023443-pvz7dll9	349	9	proliferating	proliferate	VBG
cord-023443-pvz7dll9	349	10	cells	cell	NNS
cord-023443-pvz7dll9	349	11	4	4	CD
cord-023443-pvz7dll9	349	12	h	h	NN
cord-023443-pvz7dll9	349	13	after	after	IN
cord-023443-pvz7dll9	349	14	elicitation	elicitation	NN
cord-023443-pvz7dll9	349	15	.	.	.
cord-023443-pvz7dll9	350	1	After	after	IN
cord-023443-pvz7dll9	350	2	24	24	CD
cord-023443-pvz7dll9	350	3	h	h	NN
cord-023443-pvz7dll9	350	4	,	,	,
cord-023443-pvz7dll9	350	5	these	these	DT
cord-023443-pvz7dll9	350	6	cells	cell	NNS
cord-023443-pvz7dll9	350	7	were	be	VBD
cord-023443-pvz7dll9	350	8	found	find	VBN
cord-023443-pvz7dll9	350	9	frequently	frequently	RB
cord-023443-pvz7dll9	350	10	in	in	IN
cord-023443-pvz7dll9	350	11	the	the	DT
cord-023443-pvz7dll9	350	12	whole	whole	JJ
cord-023443-pvz7dll9	350	13	lymph	lymph	NN
cord-023443-pvz7dll9	350	14	node	node	NN
cord-023443-pvz7dll9	350	15	.	.	.
cord-023443-pvz7dll9	351	1	Control	control	NN
cord-023443-pvz7dll9	351	2	animals	animal	NNS
cord-023443-pvz7dll9	351	3	exhibited	exhibit	VBD
cord-023443-pvz7dll9	351	4	considerable	considerable	JJ
cord-023443-pvz7dll9	351	5	less	less	RBR
cord-023443-pvz7dll9	351	6	proliferating	proliferate	VBG
cord-023443-pvz7dll9	351	7	cells	cell	NNS
cord-023443-pvz7dll9	351	8	at	at	IN
cord-023443-pvz7dll9	351	9	all	all	DT
cord-023443-pvz7dll9	351	10	times	time	NNS
cord-023443-pvz7dll9	351	11	.	.	.
cord-023443-pvz7dll9	352	1	We	-PRON-	PRP
cord-023443-pvz7dll9	352	2	conclude	conclude	VBP
cord-023443-pvz7dll9	352	3	that	that	IN
cord-023443-pvz7dll9	352	4	most	most	RBS
cord-023443-pvz7dll9	352	5	proliferating	proliferate	VBG
cord-023443-pvz7dll9	352	6	cells	cell	NNS
cord-023443-pvz7dll9	352	7	were	be	VBD
cord-023443-pvz7dll9	352	8	found	find	VBN
cord-023443-pvz7dll9	352	9	24	24	CD
cord-023443-pvz7dll9	352	10	h	h	NN
cord-023443-pvz7dll9	352	11	after	after	IN
cord-023443-pvz7dll9	352	12	elicitation	elicitation	NN
cord-023443-pvz7dll9	352	13	locally	locally	RB
cord-023443-pvz7dll9	352	14	at	at	IN
cord-023443-pvz7dll9	352	15	the	the	DT
cord-023443-pvz7dll9	352	16	hapten	hapten	NN
cord-023443-pvz7dll9	352	17	-	-	HYPH
cord-023443-pvz7dll9	352	18	exposed	expose	VBN
cord-023443-pvz7dll9	352	19	sites	site	NNS
cord-023443-pvz7dll9	352	20	(	(	-LRB-
cord-023443-pvz7dll9	352	21	the	the	DT
cord-023443-pvz7dll9	352	22	oral	oral	JJ
cord-023443-pvz7dll9	352	23	mucosa	mucosa	NN
cord-023443-pvz7dll9	352	24	or	or	CC
cord-023443-pvz7dll9	352	25	the	the	DT
cord-023443-pvz7dll9	352	26	ear	ear	NN
cord-023443-pvz7dll9	352	27	skin	skin	NN
cord-023443-pvz7dll9	352	28	)	)	-RRB-
cord-023443-pvz7dll9	352	29	as	as	RB
cord-023443-pvz7dll9	352	30	well	well	RB
cord-023443-pvz7dll9	352	31	as	as	IN
cord-023443-pvz7dll9	352	32	in	in	IN
cord-023443-pvz7dll9	352	33	the	the	DT
cord-023443-pvz7dll9	352	34	regional	regional	JJ
cord-023443-pvz7dll9	352	35	lymph	lymph	NN
cord-023443-pvz7dll9	352	36	nodes	node	NNS
cord-023443-pvz7dll9	352	37	.	.	.
cord-023443-pvz7dll9	353	1	The	the	DT
cord-023443-pvz7dll9	353	2	endogenous	endogenous	JJ
cord-023443-pvz7dll9	353	3	nucleoside	nucleoside	NN
cord-023443-pvz7dll9	353	4	adenosine	adenosine	NN
cord-023443-pvz7dll9	353	5	is	be	VBZ
cord-023443-pvz7dll9	353	6	released	release	VBN
cord-023443-pvz7dll9	353	7	in	in	IN
cord-023443-pvz7dll9	353	8	excess	excess	NN
cord-023443-pvz7dll9	353	9	during	during	IN
cord-023443-pvz7dll9	353	10	inflammation	inflammation	NN
cord-023443-pvz7dll9	353	11	or	or	CC
cord-023443-pvz7dll9	353	12	other	other	JJ
cord-023443-pvz7dll9	353	13	metabolic	metabolic	JJ
cord-023443-pvz7dll9	353	14	stress	stress	NN
cord-023443-pvz7dll9	353	15	and	and	CC
cord-023443-pvz7dll9	353	16	is	be	VBZ
cord-023443-pvz7dll9	353	17	generally	generally	RB
cord-023443-pvz7dll9	353	18	known	know	VBN
cord-023443-pvz7dll9	353	19	to	to	TO
cord-023443-pvz7dll9	353	20	deliver	deliver	VB
cord-023443-pvz7dll9	353	21	tissue	tissue	NN
cord-023443-pvz7dll9	353	22	protective	protective	JJ
cord-023443-pvz7dll9	353	23	anti	anti	JJ
cord-023443-pvz7dll9	353	24	-	-	JJ
cord-023443-pvz7dll9	353	25	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	353	26	effects	effect	NNS
cord-023443-pvz7dll9	353	27	.	.	.
cord-023443-pvz7dll9	354	1	Adenosine	adenosine	NN
cord-023443-pvz7dll9	354	2	acts	act	VBZ
cord-023443-pvz7dll9	354	3	via	via	IN
cord-023443-pvz7dll9	354	4	four	four	CD
cord-023443-pvz7dll9	354	5	adenosine	adenosine	NN
cord-023443-pvz7dll9	354	6	receptors	receptor	NNS
cord-023443-pvz7dll9	354	7	of	of	IN
cord-023443-pvz7dll9	354	8	which	which	WDT
cord-023443-pvz7dll9	354	9	the	the	DT
cord-023443-pvz7dll9	354	10	A2a	A2a	NNP
cord-023443-pvz7dll9	354	11	receptor	receptor	NN
cord-023443-pvz7dll9	354	12	is	be	VBZ
cord-023443-pvz7dll9	354	13	the	the	DT
cord-023443-pvz7dll9	354	14	predominant	predominant	JJ
cord-023443-pvz7dll9	354	15	form	form	NN
cord-023443-pvz7dll9	354	16	in	in	IN
cord-023443-pvz7dll9	354	17	T	t	NN
cord-023443-pvz7dll9	354	18	cells	cell	NNS
cord-023443-pvz7dll9	354	19	.	.	.
cord-023443-pvz7dll9	355	1	Adenosine	adenosine	NN
cord-023443-pvz7dll9	355	2	levels	level	NNS
cord-023443-pvz7dll9	355	3	are	be	VBP
cord-023443-pvz7dll9	355	4	elevated	elevate	VBN
cord-023443-pvz7dll9	355	5	in	in	IN
cord-023443-pvz7dll9	355	6	asthmatic	asthmatic	JJ
cord-023443-pvz7dll9	355	7	lung	lung	NN
cord-023443-pvz7dll9	355	8	,	,	,
cord-023443-pvz7dll9	355	9	and	and	CC
cord-023443-pvz7dll9	355	10	adenosine	adenosine	NN
cord-023443-pvz7dll9	355	11	can	can	MD
cord-023443-pvz7dll9	355	12	directly	directly	RB
cord-023443-pvz7dll9	355	13	induce	induce	VB
cord-023443-pvz7dll9	355	14	mast	mast	JJ
cord-023443-pvz7dll9	355	15	cell	cell	NN
cord-023443-pvz7dll9	355	16	degranulation	degranulation	NN
cord-023443-pvz7dll9	355	17	and	and	CC
cord-023443-pvz7dll9	355	18	bronchoconstriction	bronchoconstriction	NN
cord-023443-pvz7dll9	355	19	in	in	IN
cord-023443-pvz7dll9	355	20	these	these	DT
cord-023443-pvz7dll9	355	21	patients	patient	NNS
cord-023443-pvz7dll9	355	22	.	.	.
cord-023443-pvz7dll9	356	1	Instead	instead	RB
cord-023443-pvz7dll9	356	2	,	,	,
cord-023443-pvz7dll9	356	3	the	the	DT
cord-023443-pvz7dll9	356	4	role	role	NN
cord-023443-pvz7dll9	356	5	of	of	IN
cord-023443-pvz7dll9	356	6	anti	anti	JJ
cord-023443-pvz7dll9	356	7	-	-	JJ
cord-023443-pvz7dll9	356	8	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	356	9	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	356	10	of	of	IN
cord-023443-pvz7dll9	356	11	adenosine	adenosine	NN
cord-023443-pvz7dll9	356	12	on	on	IN
cord-023443-pvz7dll9	356	13	T	T	NNP
cord-023443-pvz7dll9	356	14	cells	cell	NNS
cord-023443-pvz7dll9	356	15	in	in	IN
cord-023443-pvz7dll9	356	16	asthma	asthma	NN
cord-023443-pvz7dll9	356	17	is	be	VBZ
cord-023443-pvz7dll9	356	18	unclear	unclear	JJ
cord-023443-pvz7dll9	356	19	.	.	.
cord-023443-pvz7dll9	357	1	Aim	aim	VB
cord-023443-pvz7dll9	357	2	:	:	:
cord-023443-pvz7dll9	357	3	To	to	TO
cord-023443-pvz7dll9	357	4	study	study	VB
cord-023443-pvz7dll9	357	5	the	the	DT
cord-023443-pvz7dll9	357	6	A2a	A2a	NNP
cord-023443-pvz7dll9	357	7	receptor	receptor	NN
cord-023443-pvz7dll9	357	8	expression	expression	NN
cord-023443-pvz7dll9	357	9	in	in	IN
cord-023443-pvz7dll9	357	10	peripheral	peripheral	JJ
cord-023443-pvz7dll9	357	11	blood	blood	NN
cord-023443-pvz7dll9	357	12	CD4	CD4	NNP
cord-023443-pvz7dll9	357	13	þ	þ	NNP
cord-023443-pvz7dll9	357	14	T	t	NN
cord-023443-pvz7dll9	357	15	cells	cell	NNS
cord-023443-pvz7dll9	357	16	in	in	IN
cord-023443-pvz7dll9	357	17	asthmatic	asthmatic	JJ
cord-023443-pvz7dll9	357	18	and	and	CC
cord-023443-pvz7dll9	357	19	healthy	healthy	JJ
cord-023443-pvz7dll9	357	20	individuals	individual	NNS
cord-023443-pvz7dll9	357	21	using	use	VBG
cord-023443-pvz7dll9	357	22	flow	flow	NN
cord-023443-pvz7dll9	357	23	cytometric	cytometric	JJ
cord-023443-pvz7dll9	357	24	and	and	CC
cord-023443-pvz7dll9	357	25	quantitative	quantitative	JJ
cord-023443-pvz7dll9	357	26	real	real	JJ
cord-023443-pvz7dll9	357	27	-	-	HYPH
cord-023443-pvz7dll9	357	28	time	time	NN
cord-023443-pvz7dll9	357	29	PCR	pcr	NN
cord-023443-pvz7dll9	357	30	methods	method	NNS
cord-023443-pvz7dll9	357	31	.	.	.
cord-023443-pvz7dll9	358	1	Results	result	NNS
cord-023443-pvz7dll9	358	2	:	:	:
cord-023443-pvz7dll9	359	1	Unstimulated	unstimulated	JJ
cord-023443-pvz7dll9	359	2	CD4	CD4	NNP
cord-023443-pvz7dll9	359	3	þ	þ	NNP
cord-023443-pvz7dll9	359	4	cells	cell	NNS
cord-023443-pvz7dll9	359	5	of	of	IN
cord-023443-pvz7dll9	359	6	asthmatic	asthmatic	JJ
cord-023443-pvz7dll9	359	7	patients	patient	NNS
cord-023443-pvz7dll9	359	8	expressed	express	VBD
cord-023443-pvz7dll9	359	9	significantly	significantly	RB
cord-023443-pvz7dll9	359	10	lower	low	JJR
cord-023443-pvz7dll9	359	11	levels	level	NNS
cord-023443-pvz7dll9	359	12	(	(	-LRB-
cord-023443-pvz7dll9	359	13	P	p	NN
cord-023443-pvz7dll9	359	14	<	<	XX
cord-023443-pvz7dll9	359	15	0.001	0.001	CD
cord-023443-pvz7dll9	359	16	)	)	-RRB-
cord-023443-pvz7dll9	359	17	of	of	IN
cord-023443-pvz7dll9	359	18	A2a	a2a	CD
cord-023443-pvz7dll9	359	19	receptor	receptor	NN
cord-023443-pvz7dll9	359	20	in	in	IN
cord-023443-pvz7dll9	359	21	protein	protein	NN
cord-023443-pvz7dll9	359	22	level	level	NN
cord-023443-pvz7dll9	359	23	(	(	-LRB-
cord-023443-pvz7dll9	359	24	mean	mean	JJ
cord-023443-pvz7dll9	359	25	percentage	percentage	NN
cord-023443-pvz7dll9	359	26	of	of	IN
cord-023443-pvz7dll9	359	27	cells	cell	NNS
cord-023443-pvz7dll9	359	28	positive	positive	JJ
cord-023443-pvz7dll9	359	29	AE	AE	NNP
cord-023443-pvz7dll9	359	30	SEM	SEM	NNP
cord-023443-pvz7dll9	359	31	:	:	:
cord-023443-pvz7dll9	359	32	76.8	76.8	CD
cord-023443-pvz7dll9	359	33	AE	AE	NNP
cord-023443-pvz7dll9	359	34	1.2	1.2	CD
cord-023443-pvz7dll9	359	35	,	,	,
cord-023443-pvz7dll9	359	36	n	n	NN
cord-023443-pvz7dll9	359	37	¼	¼	NNP
cord-023443-pvz7dll9	359	38	6	6	CD
cord-023443-pvz7dll9	359	39	)	)	-RRB-
cord-023443-pvz7dll9	359	40	compared	compare	VBN
cord-023443-pvz7dll9	359	41	to	to	IN
cord-023443-pvz7dll9	359	42	healthy	healthy	JJ
cord-023443-pvz7dll9	359	43	individuals	individual	NNS
cord-023443-pvz7dll9	359	44	(	(	-LRB-
cord-023443-pvz7dll9	359	45	90.4	90.4	CD
cord-023443-pvz7dll9	359	46	%	%	NN
cord-023443-pvz7dll9	359	47	AE	AE	NNP
cord-023443-pvz7dll9	359	48	1.9	1.9	CD
cord-023443-pvz7dll9	359	49	,	,	,
cord-023443-pvz7dll9	359	50	n	n	NN
cord-023443-pvz7dll9	359	51	¼	¼	NNP
cord-023443-pvz7dll9	359	52	4	4	CD
cord-023443-pvz7dll9	359	53	)	)	-RRB-
cord-023443-pvz7dll9	359	54	.	.	.
cord-023443-pvz7dll9	360	1	Double	double	JJ
cord-023443-pvz7dll9	360	2	staining	staining	NN
cord-023443-pvz7dll9	360	3	for	for	IN
cord-023443-pvz7dll9	360	4	CD69	CD69	NNP
cord-023443-pvz7dll9	360	5	expression	expression	NN
cord-023443-pvz7dll9	360	6	showed	show	VBD
cord-023443-pvz7dll9	360	7	that	that	IN
cord-023443-pvz7dll9	360	8	stimulation	stimulation	NN
cord-023443-pvz7dll9	360	9	of	of	IN
cord-023443-pvz7dll9	360	10	CD4	CD4	NNP
cord-023443-pvz7dll9	360	11	þ	þ	NNP
cord-023443-pvz7dll9	360	12	cells	cell	NNS
cord-023443-pvz7dll9	360	13	decreased	decrease	VBD
cord-023443-pvz7dll9	360	14	A2a	a2a	DT
cord-023443-pvz7dll9	360	15	expression	expression	NN
cord-023443-pvz7dll9	360	16	in	in	IN
cord-023443-pvz7dll9	360	17	both	both	DT
cord-023443-pvz7dll9	360	18	groups	group	NNS
cord-023443-pvz7dll9	360	19	but	but	CC
cord-023443-pvz7dll9	360	20	indicated	indicate	VBD
cord-023443-pvz7dll9	360	21	that	that	IN
cord-023443-pvz7dll9	360	22	the	the	DT
cord-023443-pvz7dll9	360	23	detected	detect	VBN
cord-023443-pvz7dll9	360	24	lower	low	JJR
cord-023443-pvz7dll9	360	25	levels	level	NNS
cord-023443-pvz7dll9	360	26	of	of	IN
cord-023443-pvz7dll9	360	27	A2a	a2a	CD
cord-023443-pvz7dll9	360	28	in	in	IN
cord-023443-pvz7dll9	360	29	unstimulated	unstimulated	JJ
cord-023443-pvz7dll9	360	30	cells	cell	NNS
cord-023443-pvz7dll9	360	31	of	of	IN
cord-023443-pvz7dll9	360	32	asthmatics	asthmatic	NNS
cord-023443-pvz7dll9	360	33	was	be	VBD
cord-023443-pvz7dll9	360	34	not	not	RB
cord-023443-pvz7dll9	360	35	due	due	JJ
cord-023443-pvz7dll9	360	36	to	to	IN
cord-023443-pvz7dll9	360	37	preactivation	preactivation	NN
cord-023443-pvz7dll9	360	38	in	in	IN
cord-023443-pvz7dll9	360	39	these	these	DT
cord-023443-pvz7dll9	360	40	patients	patient	NNS
cord-023443-pvz7dll9	360	41	.	.	.
cord-023443-pvz7dll9	361	1	Surprisingly	surprisingly	RB
cord-023443-pvz7dll9	361	2	,	,	,
cord-023443-pvz7dll9	361	3	A2a	a2a	DT
cord-023443-pvz7dll9	361	4	mRNA	mrna	NN
cord-023443-pvz7dll9	361	5	expression	expression	NN
cord-023443-pvz7dll9	361	6	in	in	IN
cord-023443-pvz7dll9	361	7	unstimulated	unstimulated	JJ
cord-023443-pvz7dll9	361	8	CD4	CD4	NNP
cord-023443-pvz7dll9	361	9	þ	þ	NNP
cord-023443-pvz7dll9	361	10	cells	cell	NNS
cord-023443-pvz7dll9	361	11	was	be	VBD
cord-023443-pvz7dll9	361	12	significantly	significantly	RB
cord-023443-pvz7dll9	361	13	higher	high	JJR
cord-023443-pvz7dll9	361	14	(	(	-LRB-
cord-023443-pvz7dll9	361	15	P	p	NN
cord-023443-pvz7dll9	361	16	<	<	XX
cord-023443-pvz7dll9	361	17	0.05	0.05	CD
cord-023443-pvz7dll9	361	18	)	)	-RRB-
cord-023443-pvz7dll9	361	19	in	in	IN
cord-023443-pvz7dll9	361	20	asthmatics	asthmatic	NNS
cord-023443-pvz7dll9	361	21	(	(	-LRB-
cord-023443-pvz7dll9	361	22	n	n	CC
cord-023443-pvz7dll9	361	23	¼	¼	NNP
cord-023443-pvz7dll9	361	24	28	28	CD
cord-023443-pvz7dll9	361	25	)	)	-RRB-
cord-023443-pvz7dll9	361	26	compared	compare	VBN
cord-023443-pvz7dll9	361	27	to	to	IN
cord-023443-pvz7dll9	361	28	healthy	healthy	JJ
cord-023443-pvz7dll9	361	29	controls	control	NNS
cord-023443-pvz7dll9	361	30	(	(	-LRB-
cord-023443-pvz7dll9	361	31	n	n	CC
cord-023443-pvz7dll9	361	32	¼	¼	NNP
cord-023443-pvz7dll9	361	33	7	7	CD
cord-023443-pvz7dll9	361	34	)	)	-RRB-
cord-023443-pvz7dll9	361	35	.	.	.
cord-023443-pvz7dll9	362	1	The	the	DT
cord-023443-pvz7dll9	362	2	expression	expression	NN
cord-023443-pvz7dll9	362	3	did	do	VBD
cord-023443-pvz7dll9	362	4	not	not	RB
cord-023443-pvz7dll9	362	5	correlate	correlate	VB
cord-023443-pvz7dll9	362	6	with	with	IN
cord-023443-pvz7dll9	362	7	serum	serum	NNP
cord-023443-pvz7dll9	362	8	total	total	JJ
cord-023443-pvz7dll9	362	9	IgE	IgE	NNP
cord-023443-pvz7dll9	362	10	levels	level	NNS
cord-023443-pvz7dll9	362	11	.	.	.
cord-023443-pvz7dll9	363	1	Conclusions	conclusion	NNS
cord-023443-pvz7dll9	363	2	:	:	:
cord-023443-pvz7dll9	364	1	Asthmatic	asthmatic	JJ
cord-023443-pvz7dll9	364	2	individuals	individual	NNS
cord-023443-pvz7dll9	364	3	express	express	VBP
cord-023443-pvz7dll9	364	4	less	less	RBR
cord-023443-pvz7dll9	364	5	A2a	a2a	CD
cord-023443-pvz7dll9	364	6	adenosine	adenosine	NN
cord-023443-pvz7dll9	364	7	receptor	receptor	NN
cord-023443-pvz7dll9	364	8	on	on	IN
cord-023443-pvz7dll9	364	9	their	-PRON-	PRP$
cord-023443-pvz7dll9	364	10	peripheral	peripheral	JJ
cord-023443-pvz7dll9	364	11	CD4	CD4	NNP
cord-023443-pvz7dll9	364	12	þ	þ	NNP
cord-023443-pvz7dll9	364	13	T	t	NN
cord-023443-pvz7dll9	364	14	cells	cell	NNS
cord-023443-pvz7dll9	364	15	.	.	.
cord-023443-pvz7dll9	365	1	The	the	DT
cord-023443-pvz7dll9	365	2	higher	high	JJR
cord-023443-pvz7dll9	365	3	mRNA	mrna	NN
cord-023443-pvz7dll9	365	4	levels	level	NNS
cord-023443-pvz7dll9	365	5	instead	instead	RB
cord-023443-pvz7dll9	365	6	may	may	MD
cord-023443-pvz7dll9	365	7	point	point	VB
cord-023443-pvz7dll9	365	8	to	to	IN
cord-023443-pvz7dll9	365	9	a	a	DT
cord-023443-pvz7dll9	365	10	negative	negative	JJ
cord-023443-pvz7dll9	365	11	feedback	feedback	NN
cord-023443-pvz7dll9	365	12	regulation	regulation	NN
cord-023443-pvz7dll9	365	13	in	in	IN
cord-023443-pvz7dll9	365	14	the	the	DT
cord-023443-pvz7dll9	365	15	receptor	receptor	NN
cord-023443-pvz7dll9	365	16	expression	expression	NN
cord-023443-pvz7dll9	365	17	.	.	.
cord-023443-pvz7dll9	366	1	The	the	DT
cord-023443-pvz7dll9	366	2	role	role	NN
cord-023443-pvz7dll9	366	3	of	of	IN
cord-023443-pvz7dll9	366	4	possibly	possibly	RB
cord-023443-pvz7dll9	366	5	decreased	decrease	VBD
cord-023443-pvz7dll9	366	6	adenosine	adenosine	NN
cord-023443-pvz7dll9	366	7	-	-	HYPH
cord-023443-pvz7dll9	366	8	mediated	mediate	VBN
cord-023443-pvz7dll9	366	9	anti	anti	JJ
cord-023443-pvz7dll9	366	10	-	-	JJ
cord-023443-pvz7dll9	366	11	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	366	12	effects	effect	NNS
cord-023443-pvz7dll9	366	13	in	in	IN
cord-023443-pvz7dll9	366	14	asthma	asthma	NN
cord-023443-pvz7dll9	366	15	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	366	16	require	require	VBP
cord-023443-pvz7dll9	366	17	further	further	JJ
cord-023443-pvz7dll9	366	18	studies	study	NNS
cord-023443-pvz7dll9	366	19	on	on	IN
cord-023443-pvz7dll9	366	20	this	this	DT
cord-023443-pvz7dll9	366	21	T	t	NN
cord-023443-pvz7dll9	366	22	-	-	HYPH
cord-023443-pvz7dll9	366	23	cell	cell	NN
cord-023443-pvz7dll9	366	24	mediated	mediate	VBN
cord-023443-pvz7dll9	366	25	disease	disease	NN
cord-023443-pvz7dll9	366	26	.	.	.
cord-023443-pvz7dll9	367	1	The	the	DT
cord-023443-pvz7dll9	367	2	chronic	chronic	JJ
cord-023443-pvz7dll9	367	3	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	367	4	skin	skin	NN
cord-023443-pvz7dll9	367	5	disease	disease	NN
cord-023443-pvz7dll9	367	6	atopic	atopic	NN
cord-023443-pvz7dll9	367	7	eczema	eczema	NN
cord-023443-pvz7dll9	367	8	(	(	-LRB-
cord-023443-pvz7dll9	367	9	AE	AE	NNP
cord-023443-pvz7dll9	367	10	)	)	-RRB-
cord-023443-pvz7dll9	367	11	affects	affect	VBZ
cord-023443-pvz7dll9	367	12	almost	almost	RB
cord-023443-pvz7dll9	367	13	15	15	CD
cord-023443-pvz7dll9	367	14	%	%	NN
cord-023443-pvz7dll9	367	15	of	of	IN
cord-023443-pvz7dll9	367	16	the	the	DT
cord-023443-pvz7dll9	367	17	population	population	NN
cord-023443-pvz7dll9	367	18	in	in	IN
cord-023443-pvz7dll9	367	19	many	many	JJ
cord-023443-pvz7dll9	367	20	countries	country	NNS
cord-023443-pvz7dll9	367	21	today	today	NN
cord-023443-pvz7dll9	367	22	.	.	.
cord-023443-pvz7dll9	368	1	The	the	DT
cord-023443-pvz7dll9	368	2	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	368	3	of	of	IN
cord-023443-pvz7dll9	368	4	AE	AE	NNP
cord-023443-pvz7dll9	368	5	is	be	VBZ
cord-023443-pvz7dll9	368	6	not	not	RB
cord-023443-pvz7dll9	368	7	fully	fully	RB
cord-023443-pvz7dll9	368	8	understood	understand	VBN
cord-023443-pvz7dll9	368	9	.	.	.
cord-023443-pvz7dll9	369	1	A	a	DT
cord-023443-pvz7dll9	369	2	combination	combination	NN
cord-023443-pvz7dll9	369	3	of	of	IN
cord-023443-pvz7dll9	369	4	genetic	genetic	JJ
cord-023443-pvz7dll9	369	5	predisposition	predisposition	NN
cord-023443-pvz7dll9	369	6	and	and	CC
cord-023443-pvz7dll9	369	7	environmental	environmental	JJ
cord-023443-pvz7dll9	369	8	factors	factor	NNS
cord-023443-pvz7dll9	369	9	like	like	IN
cord-023443-pvz7dll9	369	10	microorganisms	microorganism	NNS
cord-023443-pvz7dll9	369	11	seems	seem	VBZ
cord-023443-pvz7dll9	369	12	to	to	TO
cord-023443-pvz7dll9	369	13	contribute	contribute	VB
cord-023443-pvz7dll9	369	14	to	to	IN
cord-023443-pvz7dll9	369	15	the	the	DT
cord-023443-pvz7dll9	369	16	symptoms	symptom	NNS
cord-023443-pvz7dll9	369	17	.	.	.
cord-023443-pvz7dll9	370	1	The	the	DT
cord-023443-pvz7dll9	370	2	yeast	yeast	NN
cord-023443-pvz7dll9	370	3	Malassezia	Malassezia	NNP
cord-023443-pvz7dll9	370	4	sympodialis	sympodialis	NNP
cord-023443-pvz7dll9	370	5	is	be	VBZ
cord-023443-pvz7dll9	370	6	part	part	NN
cord-023443-pvz7dll9	370	7	of	of	IN
cord-023443-pvz7dll9	370	8	our	-PRON-	PRP$
cord-023443-pvz7dll9	370	9	normal	normal	JJ
cord-023443-pvz7dll9	370	10	skin	skin	NN
cord-023443-pvz7dll9	370	11	micro	micro	NN
cord-023443-pvz7dll9	370	12	flora	flora	NN
cord-023443-pvz7dll9	370	13	but	but	CC
cord-023443-pvz7dll9	370	14	can	can	MD
cord-023443-pvz7dll9	370	15	act	act	VB
cord-023443-pvz7dll9	370	16	as	as	IN
cord-023443-pvz7dll9	370	17	an	an	DT
cord-023443-pvz7dll9	370	18	allergen	allergen	NN
cord-023443-pvz7dll9	370	19	and	and	CC
cord-023443-pvz7dll9	370	20	elicit	elicit	VB
cord-023443-pvz7dll9	370	21	specific	specific	JJ
cord-023443-pvz7dll9	370	22	IgE	IgE	NNP
cord-023443-pvz7dll9	370	23	and	and	CC
cord-023443-pvz7dll9	370	24	T	t	NN
cord-023443-pvz7dll9	370	25	-	-	HYPH
cord-023443-pvz7dll9	370	26	cell	cell	NN
cord-023443-pvz7dll9	370	27	reactivity	reactivity	NN
cord-023443-pvz7dll9	370	28	in	in	IN
cord-023443-pvz7dll9	370	29	patients	patient	NNS
cord-023443-pvz7dll9	370	30	with	with	IN
cord-023443-pvz7dll9	370	31	AE	AE	NNP
cord-023443-pvz7dll9	370	32	.	.	.
cord-023443-pvz7dll9	371	1	Recently	recently	RB
cord-023443-pvz7dll9	371	2	,	,	,
cord-023443-pvz7dll9	371	3	we	-PRON-	PRP
cord-023443-pvz7dll9	371	4	identified	identify	VBD
cord-023443-pvz7dll9	371	5	a	a	DT
cord-023443-pvz7dll9	371	6	novel	novel	JJ
cord-023443-pvz7dll9	371	7	major	major	JJ
cord-023443-pvz7dll9	371	8	M.	M.	NNP
cord-023443-pvz7dll9	371	9	sympodialis	sympodialis	JJ
cord-023443-pvz7dll9	371	10	allergen	allergen	NN
cord-023443-pvz7dll9	371	11	,	,	,
cord-023443-pvz7dll9	371	12	designated	designate	VBN
cord-023443-pvz7dll9	371	13	Mala	Mala	NNP
cord-023443-pvz7dll9	371	14	s	s	POS
cord-023443-pvz7dll9	371	15	11	11	CD
cord-023443-pvz7dll9	371	16	(	(	-LRB-
cord-023443-pvz7dll9	371	17	22.4	22.4	CD
cord-023443-pvz7dll9	371	18	kDa	kDa	NNPS
cord-023443-pvz7dll9	371	19	)	)	-RRB-
cord-023443-pvz7dll9	371	20	,	,	,
cord-023443-pvz7dll9	371	21	with	with	IN
cord-023443-pvz7dll9	371	22	sequence	sequence	NN
cord-023443-pvz7dll9	371	23	similarity	similarity	NN
cord-023443-pvz7dll9	371	24	to	to	IN
cord-023443-pvz7dll9	371	25	the	the	DT
cord-023443-pvz7dll9	371	26	mitochondrial	mitochondrial	JJ
cord-023443-pvz7dll9	371	27	enzyme	enzyme	NN
cord-023443-pvz7dll9	371	28	manganese	manganese	NN
cord-023443-pvz7dll9	371	29	superoxide	superoxide	NN
cord-023443-pvz7dll9	371	30	dismutase	dismutase	NN
cord-023443-pvz7dll9	371	31	(	(	-LRB-
cord-023443-pvz7dll9	371	32	MnSOD	MnSOD	NNP
cord-023443-pvz7dll9	371	33	)	)	-RRB-
cord-023443-pvz7dll9	371	34	.	.	.
cord-023443-pvz7dll9	372	1	Interestingly	interestingly	RB
cord-023443-pvz7dll9	372	2	,	,	,
cord-023443-pvz7dll9	372	3	Mala	Mala	NNP
cord-023443-pvz7dll9	372	4	s	s	POS
cord-023443-pvz7dll9	372	5	11	11	CD
cord-023443-pvz7dll9	372	6	has	have	VBZ
cord-023443-pvz7dll9	372	7	a	a	DT
cord-023443-pvz7dll9	372	8	high	high	JJ
cord-023443-pvz7dll9	372	9	degree	degree	NN
cord-023443-pvz7dll9	372	10	of	of	IN
cord-023443-pvz7dll9	372	11	homology	homology	NN
cord-023443-pvz7dll9	372	12	to	to	IN
cord-023443-pvz7dll9	372	13	human	human	JJ
cord-023443-pvz7dll9	372	14	MnSOD	MnSOD	NNP
cord-023443-pvz7dll9	372	15	.	.	.
cord-023443-pvz7dll9	373	1	The	the	DT
cord-023443-pvz7dll9	373	2	aim	aim	NN
cord-023443-pvz7dll9	373	3	of	of	IN
cord-023443-pvz7dll9	373	4	this	this	DT
cord-023443-pvz7dll9	373	5	study	study	NN
cord-023443-pvz7dll9	373	6	was	be	VBD
cord-023443-pvz7dll9	373	7	to	to	TO
cord-023443-pvz7dll9	373	8	examine	examine	VB
cord-023443-pvz7dll9	373	9	the	the	DT
cord-023443-pvz7dll9	373	10	effects	effect	NNS
cord-023443-pvz7dll9	373	11	of	of	IN
cord-023443-pvz7dll9	373	12	recombinant	recombinant	JJ
cord-023443-pvz7dll9	373	13	Mala	Mala	NNP
cord-023443-pvz7dll9	373	14	s	s	POS
cord-023443-pvz7dll9	373	15	11	11	CD
cord-023443-pvz7dll9	373	16	on	on	IN
cord-023443-pvz7dll9	373	17	antigen	antigen	NN
cord-023443-pvz7dll9	373	18	-	-	HYPH
cord-023443-pvz7dll9	373	19	presenting	present	VBG
cord-023443-pvz7dll9	373	20	dendritic	dendritic	JJ
cord-023443-pvz7dll9	373	21	cells	cell	NNS
cord-023443-pvz7dll9	373	22	.	.	.
cord-023443-pvz7dll9	374	1	Monocytederived	monocytederived	JJ
cord-023443-pvz7dll9	374	2	dendritic	dendritic	JJ
cord-023443-pvz7dll9	374	3	cells	cell	NNS
cord-023443-pvz7dll9	374	4	(	(	-LRB-
cord-023443-pvz7dll9	374	5	MDDCs	mddc	NNS
cord-023443-pvz7dll9	374	6	)	)	-RRB-
cord-023443-pvz7dll9	374	7	from	from	IN
cord-023443-pvz7dll9	374	8	healthy	healthy	JJ
cord-023443-pvz7dll9	374	9	blood	blood	NN
cord-023443-pvz7dll9	374	10	donors	donor	NNS
cord-023443-pvz7dll9	374	11	were	be	VBD
cord-023443-pvz7dll9	374	12	cultured	culture	VBN
cord-023443-pvz7dll9	374	13	with	with	IN
cord-023443-pvz7dll9	374	14	or	or	CC
cord-023443-pvz7dll9	374	15	without	without	IN
cord-023443-pvz7dll9	374	16	Mala	Mala	NNP
cord-023443-pvz7dll9	374	17	s	s	NNP
cord-023443-pvz7dll9	374	18	11	11	CD
cord-023443-pvz7dll9	374	19	for	for	IN
cord-023443-pvz7dll9	374	20	different	different	JJ
cord-023443-pvz7dll9	374	21	time	time	NN
cord-023443-pvz7dll9	374	22	periods	period	NNS
cord-023443-pvz7dll9	374	23	.	.	.
cord-023443-pvz7dll9	375	1	It	-PRON-	PRP
cord-023443-pvz7dll9	375	2	was	be	VBD
cord-023443-pvz7dll9	375	3	found	find	VBN
cord-023443-pvz7dll9	375	4	that	that	IN
cord-023443-pvz7dll9	375	5	the	the	DT
cord-023443-pvz7dll9	375	6	maturation	maturation	NN
cord-023443-pvz7dll9	375	7	marker	marker	NN
cord-023443-pvz7dll9	375	8	CD83	CD83	NNP
cord-023443-pvz7dll9	375	9	and	and	CC
cord-023443-pvz7dll9	375	10	the	the	DT
cord-023443-pvz7dll9	375	11	costimulatory	costimulatory	NN
cord-023443-pvz7dll9	375	12	molecules	molecule	NNS
cord-023443-pvz7dll9	375	13	CD80	CD80	NNP
cord-023443-pvz7dll9	375	14	and	and	CC
cord-023443-pvz7dll9	375	15	CD86	CD86	NNP
cord-023443-pvz7dll9	375	16	were	be	VBD
cord-023443-pvz7dll9	375	17	upregulated	upregulate	VBN
cord-023443-pvz7dll9	375	18	on	on	IN
cord-023443-pvz7dll9	375	19	the	the	DT
cord-023443-pvz7dll9	375	20	MDDCs	mddc	NNS
cord-023443-pvz7dll9	375	21	exposed	expose	VBN
cord-023443-pvz7dll9	375	22	to	to	IN
cord-023443-pvz7dll9	375	23	Mala	Mala	NNP
cord-023443-pvz7dll9	375	24	s	s	NNP
cord-023443-pvz7dll9	375	25	11	11	CD
cord-023443-pvz7dll9	375	26	for	for	IN
cord-023443-pvz7dll9	375	27	24	24	CD
cord-023443-pvz7dll9	375	28	h	h	NNP
cord-023443-pvz7dll9	375	29	,	,	,
cord-023443-pvz7dll9	375	30	as	as	IN
cord-023443-pvz7dll9	375	31	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	375	32	by	by	IN
cord-023443-pvz7dll9	375	33	flow	flow	NN
cord-023443-pvz7dll9	375	34	cytometry	cytometry	NN
cord-023443-pvz7dll9	375	35	.	.	.
cord-023443-pvz7dll9	376	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	376	2	,	,	,
cord-023443-pvz7dll9	376	3	coculture	coculture	NN
cord-023443-pvz7dll9	376	4	of	of	IN
cord-023443-pvz7dll9	376	5	MDDCs	mddc	NNS
cord-023443-pvz7dll9	376	6	with	with	IN
cord-023443-pvz7dll9	376	7	Mala	Mala	NNP
cord-023443-pvz7dll9	376	8	s	s	NNP
cord-023443-pvz7dll9	376	9	11	11	CD
cord-023443-pvz7dll9	376	10	for	for	IN
cord-023443-pvz7dll9	376	11	9	9	CD
cord-023443-pvz7dll9	376	12	h	h	NN
cord-023443-pvz7dll9	376	13	induced	induce	VBD
cord-023443-pvz7dll9	376	14	an	an	DT
cord-023443-pvz7dll9	376	15	increased	increase	VBN
cord-023443-pvz7dll9	376	16	production	production	NN
cord-023443-pvz7dll9	376	17	of	of	IN
cord-023443-pvz7dll9	376	18	the	the	DT
cord-023443-pvz7dll9	376	19	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	376	20	cytokines	cytokine	NNS
cord-023443-pvz7dll9	376	21	IL-6	IL-6	NNP
cord-023443-pvz7dll9	376	22	(	(	-LRB-
cord-023443-pvz7dll9	376	23	200-fold	200-fold	CD
cord-023443-pvz7dll9	376	24	)	)	-RRB-
cord-023443-pvz7dll9	376	25	,	,	,
cord-023443-pvz7dll9	376	26	TNF	TNF	NNP
cord-023443-pvz7dll9	376	27	-	-	,
cord-023443-pvz7dll9	376	28	a	a	NNP
cord-023443-pvz7dll9	376	29	(	(	-LRB-
cord-023443-pvz7dll9	376	30	100-fold	100-fold	CD
cord-023443-pvz7dll9	376	31	)	)	-RRB-
cord-023443-pvz7dll9	376	32	and	and	CC
cord-023443-pvz7dll9	376	33	IL-8	IL-8	NNP
cord-023443-pvz7dll9	376	34	(	(	-LRB-
cord-023443-pvz7dll9	376	35	sixfold	sixfold	RB
cord-023443-pvz7dll9	376	36	)	)	-RRB-
cord-023443-pvz7dll9	376	37	,	,	,
cord-023443-pvz7dll9	376	38	as	as	IN
cord-023443-pvz7dll9	376	39	detected	detect	VBN
cord-023443-pvz7dll9	376	40	by	by	IN
cord-023443-pvz7dll9	376	41	the	the	DT
cord-023443-pvz7dll9	376	42	cytometric	cytometric	NNP
cord-023443-pvz7dll9	376	43	bead	bead	NN
cord-023443-pvz7dll9	376	44	array	array	NN
cord-023443-pvz7dll9	376	45	(	(	-LRB-
cord-023443-pvz7dll9	376	46	CBA	CBA	NNP
cord-023443-pvz7dll9	376	47	)	)	-RRB-
cord-023443-pvz7dll9	376	48	analysis	analysis	NN
cord-023443-pvz7dll9	376	49	.	.	.
cord-023443-pvz7dll9	377	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	377	2	results	result	NNS
cord-023443-pvz7dll9	377	3	suggest	suggest	VBP
cord-023443-pvz7dll9	377	4	that	that	IN
cord-023443-pvz7dll9	377	5	Mala	Mala	NNP
cord-023443-pvz7dll9	377	6	s	s	POS
cord-023443-pvz7dll9	377	7	11	11	CD
cord-023443-pvz7dll9	377	8	affects	affect	VBZ
cord-023443-pvz7dll9	377	9	the	the	DT
cord-023443-pvz7dll9	377	10	immune	immune	JJ
cord-023443-pvz7dll9	377	11	response	response	NN
cord-023443-pvz7dll9	377	12	through	through	IN
cord-023443-pvz7dll9	377	13	DC	DC	NNP
cord-023443-pvz7dll9	377	14	maturation	maturation	NN
cord-023443-pvz7dll9	377	15	and	and	CC
cord-023443-pvz7dll9	377	16	production	production	NN
cord-023443-pvz7dll9	377	17	of	of	IN
cord-023443-pvz7dll9	377	18	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	377	19	cytokines	cytokine	NNS
cord-023443-pvz7dll9	377	20	.	.	.
cord-023443-pvz7dll9	378	1	The	the	DT
cord-023443-pvz7dll9	378	2	potential	potential	JJ
cord-023443-pvz7dll9	378	3	cross	cross	NN
cord-023443-pvz7dll9	378	4	-	-	NN
cord-023443-pvz7dll9	378	5	reactivity	reactivity	NN
cord-023443-pvz7dll9	378	6	with	with	IN
cord-023443-pvz7dll9	378	7	human	human	JJ
cord-023443-pvz7dll9	378	8	MnSOD	MnSOD	NNP
cord-023443-pvz7dll9	378	9	needs	need	NNS
cord-023443-pvz7dll9	378	10	to	to	TO
cord-023443-pvz7dll9	378	11	be	be	VB
cord-023443-pvz7dll9	378	12	explored	explore	VBN
cord-023443-pvz7dll9	378	13	and	and	CC
cord-023443-pvz7dll9	378	14	the	the	DT
cord-023443-pvz7dll9	378	15	exact	exact	JJ
cord-023443-pvz7dll9	378	16	role	role	NN
cord-023443-pvz7dll9	378	17	of	of	IN
cord-023443-pvz7dll9	378	18	Mala	Mala	NNP
cord-023443-pvz7dll9	378	19	s	s	NNP
cord-023443-pvz7dll9	378	20	11	11	CD
cord-023443-pvz7dll9	378	21	in	in	IN
cord-023443-pvz7dll9	378	22	the	the	DT
cord-023443-pvz7dll9	378	23	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	378	24	of	of	IN
cord-023443-pvz7dll9	378	25	AE	AE	NNP
cord-023443-pvz7dll9	378	26	assessed	assess	VBN
cord-023443-pvz7dll9	378	27	in	in	IN
cord-023443-pvz7dll9	378	28	clinical	clinical	JJ
cord-023443-pvz7dll9	378	29	studies	study	NNS
cord-023443-pvz7dll9	378	30	involving	involve	VBG
cord-023443-pvz7dll9	378	31	skin	skin	NN
cord-023443-pvz7dll9	378	32	prick	prick	NN
cord-023443-pvz7dll9	378	33	and	and	CC
cord-023443-pvz7dll9	378	34	atopy	atopy	NN
cord-023443-pvz7dll9	378	35	patch	patch	NN
cord-023443-pvz7dll9	378	36	tests	test	NNS
cord-023443-pvz7dll9	378	37	.	.	.
cord-023443-pvz7dll9	379	1	Allergen	allergen	NN
cord-023443-pvz7dll9	379	2	-	-	HYPH
cord-023443-pvz7dll9	379	3	specific	specific	JJ
cord-023443-pvz7dll9	379	4	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	379	5	(	(	-LRB-
cord-023443-pvz7dll9	379	6	SIT	sit	NN
cord-023443-pvz7dll9	379	7	)	)	-RRB-
cord-023443-pvz7dll9	379	8	is	be	VBZ
cord-023443-pvz7dll9	379	9	commonly	commonly	RB
cord-023443-pvz7dll9	379	10	conducted	conduct	VBN
cord-023443-pvz7dll9	379	11	with	with	IN
cord-023443-pvz7dll9	379	12	allergen	allergen	NN
cord-023443-pvz7dll9	379	13	extracts	extract	NNS
cord-023443-pvz7dll9	379	14	adsorbed	adsorb	VBN
cord-023443-pvz7dll9	379	15	to	to	IN
cord-023443-pvz7dll9	379	16	aluminium	aluminium	NN
cord-023443-pvz7dll9	379	17	hydroxide	hydroxide	NN
cord-023443-pvz7dll9	379	18	(	(	-LRB-
cord-023443-pvz7dll9	379	19	alum	alum	NN
cord-023443-pvz7dll9	379	20	)	)	-RRB-
cord-023443-pvz7dll9	379	21	.	.	.
cord-023443-pvz7dll9	380	1	Drawbacks	drawback	NNS
cord-023443-pvz7dll9	380	2	linked	link	VBN
cord-023443-pvz7dll9	380	3	to	to	IN
cord-023443-pvz7dll9	380	4	the	the	DT
cord-023443-pvz7dll9	380	5	use	use	NN
cord-023443-pvz7dll9	380	6	of	of	IN
cord-023443-pvz7dll9	380	7	alum	alum	NN
cord-023443-pvz7dll9	380	8	,	,	,
cord-023443-pvz7dll9	380	9	such	such	JJ
cord-023443-pvz7dll9	380	10	as	as	IN
cord-023443-pvz7dll9	380	11	the	the	DT
cord-023443-pvz7dll9	380	12	formation	formation	NN
cord-023443-pvz7dll9	380	13	of	of	IN
cord-023443-pvz7dll9	380	14	granuloma	granuloma	NN
cord-023443-pvz7dll9	380	15	at	at	IN
cord-023443-pvz7dll9	380	16	the	the	DT
cord-023443-pvz7dll9	380	17	site	site	NN
cord-023443-pvz7dll9	380	18	of	of	IN
cord-023443-pvz7dll9	380	19	injection	injection	NN
cord-023443-pvz7dll9	380	20	,	,	,
cord-023443-pvz7dll9	380	21	have	have	VBP
cord-023443-pvz7dll9	380	22	led	lead	VBN
cord-023443-pvz7dll9	380	23	to	to	IN
cord-023443-pvz7dll9	380	24	suggestions	suggestion	NNS
cord-023443-pvz7dll9	380	25	of	of	IN
cord-023443-pvz7dll9	380	26	novel	novel	JJ
cord-023443-pvz7dll9	380	27	allergen	allergen	NN
cord-023443-pvz7dll9	380	28	carriers	carrier	NNS
cord-023443-pvz7dll9	380	29	.	.	.
cord-023443-pvz7dll9	381	1	An	an	DT
cord-023443-pvz7dll9	381	2	alternative	alternative	JJ
cord-023443-pvz7dll9	381	3	carrier	carrier	NN
cord-023443-pvz7dll9	381	4	is	be	VBZ
cord-023443-pvz7dll9	381	5	2	2	CD
cord-023443-pvz7dll9	381	6	mm	mm	NN
cord-023443-pvz7dll9	381	7	carbohydrate	carbohydrate	NN
cord-023443-pvz7dll9	381	8	-	-	HYPH
cord-023443-pvz7dll9	381	9	based	base	VBN
cord-023443-pvz7dll9	381	10	particles	particle	NNS
cord-023443-pvz7dll9	381	11	(	(	-LRB-
cord-023443-pvz7dll9	381	12	CBPs	CBPs	NNP
cord-023443-pvz7dll9	381	13	)	)	-RRB-
cord-023443-pvz7dll9	381	14	.	.	.
cord-023443-pvz7dll9	382	1	In	in	IN
cord-023443-pvz7dll9	382	2	mouse	mouse	NN
cord-023443-pvz7dll9	382	3	,	,	,
cord-023443-pvz7dll9	382	4	allergen	allergen	NN
cord-023443-pvz7dll9	382	5	-	-	HYPH
cord-023443-pvz7dll9	382	6	coupled	couple	VBN
cord-023443-pvz7dll9	382	7	CBPs	cbp	NNS
cord-023443-pvz7dll9	382	8	have	have	VBP
cord-023443-pvz7dll9	382	9	been	be	VBN
cord-023443-pvz7dll9	382	10	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	382	11	to	to	TO
cord-023443-pvz7dll9	382	12	skew	skew	VB
cord-023443-pvz7dll9	382	13	the	the	DT
cord-023443-pvz7dll9	382	14	allergen	allergen	NN
cord-023443-pvz7dll9	382	15	-	-	HYPH
cord-023443-pvz7dll9	382	16	specific	specific	JJ
cord-023443-pvz7dll9	382	17	immune	immune	JJ
cord-023443-pvz7dll9	382	18	response	response	NN
cord-023443-pvz7dll9	382	19	towards	towards	IN
cord-023443-pvz7dll9	382	20	a	a	DT
cord-023443-pvz7dll9	382	21	Th1-like	th1-like	JJ
cord-023443-pvz7dll9	382	22	activity	activity	NN
cord-023443-pvz7dll9	382	23	(	(	-LRB-
cord-023443-pvz7dll9	382	24	Grönlund	Grönlund	NNP
cord-023443-pvz7dll9	382	25	et	et	FW
cord-023443-pvz7dll9	382	26	al	al	NNP
cord-023443-pvz7dll9	382	27	.	.	.
cord-023443-pvz7dll9	383	1	Immunology	Immunology	NNP
cord-023443-pvz7dll9	383	2	,	,	,
cord-023443-pvz7dll9	383	3	2002	2002	CD
cord-023443-pvz7dll9	383	4	)	)	-RRB-
cord-023443-pvz7dll9	383	5	.	.	.
cord-023443-pvz7dll9	384	1	We	-PRON-	PRP
cord-023443-pvz7dll9	384	2	here	here	RB
cord-023443-pvz7dll9	384	3	coupled	couple	VBD
cord-023443-pvz7dll9	384	4	the	the	DT
cord-023443-pvz7dll9	384	5	recombinant	recombinant	JJ
cord-023443-pvz7dll9	384	6	major	major	JJ
cord-023443-pvz7dll9	384	7	cat	cat	NN
cord-023443-pvz7dll9	384	8	allergen	allergen	NN
cord-023443-pvz7dll9	384	9	Fel	Fel	NNP
cord-023443-pvz7dll9	384	10	d	d	NNP
cord-023443-pvz7dll9	384	11	1	1	CD
cord-023443-pvz7dll9	384	12	to	to	IN
cord-023443-pvz7dll9	384	13	CBPs	CBPs	NNP
cord-023443-pvz7dll9	384	14	(	(	-LRB-
cord-023443-pvz7dll9	384	15	CBP	CBP	NNP
cord-023443-pvz7dll9	384	16	-	-	HYPH
cord-023443-pvz7dll9	384	17	Fel	Fel	NNP
cord-023443-pvz7dll9	384	18	d	d	NN
cord-023443-pvz7dll9	384	19	1	1	CD
cord-023443-pvz7dll9	384	20	)	)	-RRB-
cord-023443-pvz7dll9	384	21	by	by	IN
cord-023443-pvz7dll9	384	22	cyanogen	cyanogen	NN
cord-023443-pvz7dll9	384	23	-	-	HYPH
cord-023443-pvz7dll9	384	24	bromide	bromide	NN
cord-023443-pvz7dll9	384	25	activation	activation	NN
cord-023443-pvz7dll9	384	26	,	,	,
cord-023443-pvz7dll9	384	27	resulting	result	VBG
cord-023443-pvz7dll9	384	28	in	in	IN
cord-023443-pvz7dll9	384	29	covalent	covalent	JJ
cord-023443-pvz7dll9	384	30	binding	binding	NN
cord-023443-pvz7dll9	384	31	.	.	.
cord-023443-pvz7dll9	385	1	The	the	DT
cord-023443-pvz7dll9	385	2	effect	effect	NN
cord-023443-pvz7dll9	385	3	of	of	IN
cord-023443-pvz7dll9	385	4	CBP	CBP	NNP
cord-023443-pvz7dll9	385	5	-	-	HYPH
cord-023443-pvz7dll9	385	6	Fel	Fel	NNP
cord-023443-pvz7dll9	385	7	d	d	NNP
cord-023443-pvz7dll9	385	8	1	1	CD
cord-023443-pvz7dll9	385	9	on	on	IN
cord-023443-pvz7dll9	385	10	monocyte	monocyte	NNP
cord-023443-pvz7dll9	385	11	-	-	HYPH
cord-023443-pvz7dll9	385	12	derived	derive	VBN
cord-023443-pvz7dll9	385	13	dendritic	dendritic	JJ
cord-023443-pvz7dll9	385	14	cells	cell	NNS
cord-023443-pvz7dll9	385	15	(	(	-LRB-
cord-023443-pvz7dll9	385	16	MDDCs	mddc	NNS
cord-023443-pvz7dll9	385	17	)	)	-RRB-
cord-023443-pvz7dll9	385	18	from	from	IN
cord-023443-pvz7dll9	385	19	healthy	healthy	JJ
cord-023443-pvz7dll9	385	20	human	human	JJ
cord-023443-pvz7dll9	385	21	blood	blood	NN
cord-023443-pvz7dll9	385	22	donors	donor	NNS
cord-023443-pvz7dll9	385	23	was	be	VBD
cord-023443-pvz7dll9	385	24	studied	study	VBN
cord-023443-pvz7dll9	385	25	.	.	.
cord-023443-pvz7dll9	386	1	We	-PRON-	PRP
cord-023443-pvz7dll9	386	2	found	find	VBD
cord-023443-pvz7dll9	386	3	that	that	IN
cord-023443-pvz7dll9	386	4	the	the	DT
cord-023443-pvz7dll9	386	5	majority	majority	NN
cord-023443-pvz7dll9	386	6	of	of	IN
cord-023443-pvz7dll9	386	7	the	the	DT
cord-023443-pvz7dll9	386	8	CD1a	CD1a	NNP
cord-023443-pvz7dll9	386	9	þ	þ	NNP
cord-023443-pvz7dll9	386	10	MDDCs	mddc	NNS
cord-023443-pvz7dll9	386	11	were	be	VBD
cord-023443-pvz7dll9	386	12	capable	capable	JJ
cord-023443-pvz7dll9	386	13	of	of	IN
cord-023443-pvz7dll9	386	14	taking	take	VBG
cord-023443-pvz7dll9	386	15	up	up	RP
cord-023443-pvz7dll9	386	16	FITC	FITC	NNP
cord-023443-pvz7dll9	386	17	-	-	HYPH
cord-023443-pvz7dll9	386	18	labelled	label	VBN
cord-023443-pvz7dll9	386	19	CBP	CBP	NNP
cord-023443-pvz7dll9	386	20	-	-	HYPH
cord-023443-pvz7dll9	386	21	Fel	Fel	NNP
cord-023443-pvz7dll9	386	22	d	d	NN
cord-023443-pvz7dll9	386	23	1	1	CD
cord-023443-pvz7dll9	386	24	,	,	,
cord-023443-pvz7dll9	386	25	as	as	IN
cord-023443-pvz7dll9	386	26	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	386	27	by	by	IN
cord-023443-pvz7dll9	386	28	flow	flow	NN
cord-023443-pvz7dll9	386	29	cytometry	cytometry	NN
cord-023443-pvz7dll9	386	30	and	and	CC
cord-023443-pvz7dll9	386	31	confocal	confocal	JJ
cord-023443-pvz7dll9	386	32	laser	laser	NN
cord-023443-pvz7dll9	386	33	scanning	scanning	NN
cord-023443-pvz7dll9	386	34	microscopy	microscopy	NNS
cord-023443-pvz7dll9	386	35	.	.	.
cord-023443-pvz7dll9	387	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	387	2	,	,	,
cord-023443-pvz7dll9	387	3	incubation	incubation	NN
cord-023443-pvz7dll9	387	4	with	with	IN
cord-023443-pvz7dll9	387	5	CBP	CBP	NNP
cord-023443-pvz7dll9	387	6	-	-	HYPH
cord-023443-pvz7dll9	387	7	Fel	Fel	NNP
cord-023443-pvz7dll9	387	8	d	d	NNP
cord-023443-pvz7dll9	387	9	1	1	CD
cord-023443-pvz7dll9	387	10	resulted	result	VBD
cord-023443-pvz7dll9	387	11	in	in	IN
cord-023443-pvz7dll9	387	12	an	an	DT
cord-023443-pvz7dll9	387	13	upregulation	upregulation	NN
cord-023443-pvz7dll9	387	14	of	of	IN
cord-023443-pvz7dll9	387	15	the	the	DT
cord-023443-pvz7dll9	387	16	costimulatory	costimulatory	NN
cord-023443-pvz7dll9	387	17	molecule	molecule	NN
cord-023443-pvz7dll9	387	18	CD86	CD86	NNP
cord-023443-pvz7dll9	387	19	on	on	IN
cord-023443-pvz7dll9	387	20	the	the	DT
cord-023443-pvz7dll9	387	21	MDDCs	mddc	NNS
cord-023443-pvz7dll9	387	22	,	,	,
cord-023443-pvz7dll9	387	23	which	which	WDT
cord-023443-pvz7dll9	387	24	was	be	VBD
cord-023443-pvz7dll9	387	25	not	not	RB
cord-023443-pvz7dll9	387	26	observed	observe	VBN
cord-023443-pvz7dll9	387	27	with	with	IN
cord-023443-pvz7dll9	387	28	Fel	Fel	NNP
cord-023443-pvz7dll9	387	29	d	d	NNP
cord-023443-pvz7dll9	387	30	1	1	CD
cord-023443-pvz7dll9	387	31	or	or	CC
cord-023443-pvz7dll9	387	32	CBPs	cbps	NN
cord-023443-pvz7dll9	387	33	alone	alone	RB
cord-023443-pvz7dll9	387	34	.	.	.
cord-023443-pvz7dll9	388	1	Finally	finally	RB
cord-023443-pvz7dll9	388	2	,	,	,
cord-023443-pvz7dll9	388	3	CBP	CBP	NNP
cord-023443-pvz7dll9	388	4	-	-	HYPH
cord-023443-pvz7dll9	388	5	Fel	Fel	NNP
cord-023443-pvz7dll9	388	6	d	d	NNP
cord-023443-pvz7dll9	388	7	1	1	CD
cord-023443-pvz7dll9	388	8	induced	induce	VBD
cord-023443-pvz7dll9	388	9	a	a	DT
cord-023443-pvz7dll9	388	10	fivefold	fivefold	JJ
cord-023443-pvz7dll9	388	11	increase	increase	NN
cord-023443-pvz7dll9	388	12	in	in	IN
cord-023443-pvz7dll9	388	13	the	the	DT
cord-023443-pvz7dll9	388	14	release	release	NN
cord-023443-pvz7dll9	388	15	of	of	IN
cord-023443-pvz7dll9	388	16	the	the	DT
cord-023443-pvz7dll9	388	17	pro	pro	JJ
cord-023443-pvz7dll9	388	18	-	-	JJ
cord-023443-pvz7dll9	388	19	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	388	20	cytokine	cytokine	NN
cord-023443-pvz7dll9	388	21	tumour	tumour	NN
cord-023443-pvz7dll9	388	22	necrosis	necrosis	NN
cord-023443-pvz7dll9	388	23	factor	factor	NN
cord-023443-pvz7dll9	388	24	(	(	-LRB-
cord-023443-pvz7dll9	388	25	TNF)-a	TNF)-a	NNP
cord-023443-pvz7dll9	388	26	and	and	CC
cord-023443-pvz7dll9	388	27	a	a	DT
cord-023443-pvz7dll9	388	28	fourfold	fourfold	JJ
cord-023443-pvz7dll9	388	29	increase	increase	NN
cord-023443-pvz7dll9	388	30	in	in	IN
cord-023443-pvz7dll9	388	31	the	the	DT
cord-023443-pvz7dll9	388	32	release	release	NN
cord-023443-pvz7dll9	388	33	of	of	IN
cord-023443-pvz7dll9	388	34	the	the	DT
cord-023443-pvz7dll9	388	35	chemokine	chemokine	NN
cord-023443-pvz7dll9	388	36	interleukin-8	interleukin-8	NN
cord-023443-pvz7dll9	388	37	from	from	IN
cord-023443-pvz7dll9	388	38	MDDCs	mddc	NNS
cord-023443-pvz7dll9	388	39	.	.	.
cord-023443-pvz7dll9	389	1	Taken	take	VBN
cord-023443-pvz7dll9	389	2	together	together	RB
cord-023443-pvz7dll9	389	3	,	,	,
cord-023443-pvz7dll9	389	4	the	the	DT
cord-023443-pvz7dll9	389	5	effects	effect	NNS
cord-023443-pvz7dll9	389	6	CBPs	cbp	NNS
cord-023443-pvz7dll9	389	7	possess	possess	VBP
cord-023443-pvz7dll9	389	8	make	make	VB
cord-023443-pvz7dll9	389	9	them	-PRON-	PRP
cord-023443-pvz7dll9	389	10	interesting	interesting	JJ
cord-023443-pvz7dll9	389	11	as	as	IN
cord-023443-pvz7dll9	389	12	novel	novel	JJ
cord-023443-pvz7dll9	389	13	allergen	allergen	NN
cord-023443-pvz7dll9	389	14	carriers	carrier	NNS
cord-023443-pvz7dll9	389	15	for	for	IN
cord-023443-pvz7dll9	389	16	SIT	sit	NN
cord-023443-pvz7dll9	389	17	.	.	.
cord-023443-pvz7dll9	390	1	The	the	DT
cord-023443-pvz7dll9	390	2	cysteine	cysteine	NN
cord-023443-pvz7dll9	390	3	protease	protease	NN
cord-023443-pvz7dll9	390	4	Der	Der	NNP
cord-023443-pvz7dll9	390	5	p1	p1	NN
cord-023443-pvz7dll9	390	6	from	from	IN
cord-023443-pvz7dll9	390	7	dust	dust	NN
cord-023443-pvz7dll9	390	8	mite	mite	NN
cord-023443-pvz7dll9	390	9	of	of	IN
cord-023443-pvz7dll9	390	10	the	the	DT
cord-023443-pvz7dll9	390	11	genus	genus	NN
cord-023443-pvz7dll9	390	12	Dermatophagoides	Dermatophagoides	NNP
cord-023443-pvz7dll9	390	13	pteronyssinus	pteronyssinus	NNP
cord-023443-pvz7dll9	390	14	is	be	VBZ
cord-023443-pvz7dll9	390	15	a	a	DT
cord-023443-pvz7dll9	390	16	major	major	JJ
cord-023443-pvz7dll9	390	17	type	type	NN
cord-023443-pvz7dll9	390	18	I	-PRON-	PRP
cord-023443-pvz7dll9	390	19	allergen	allergen	NN
cord-023443-pvz7dll9	390	20	.	.	.
cord-023443-pvz7dll9	391	1	About	about	RB
cord-023443-pvz7dll9	391	2	80	80	CD
cord-023443-pvz7dll9	391	3	%	%	NN
cord-023443-pvz7dll9	391	4	of	of	IN
cord-023443-pvz7dll9	391	5	house	house	NN
cord-023443-pvz7dll9	391	6	dust	dust	NN
cord-023443-pvz7dll9	391	7	mite	mite	NNP
cord-023443-pvz7dll9	391	8	(	(	-LRB-
cord-023443-pvz7dll9	391	9	HDM	HDM	NNP
cord-023443-pvz7dll9	391	10	)	)	-RRB-
cord-023443-pvz7dll9	391	11	allergic	allergic	JJ
cord-023443-pvz7dll9	391	12	individuals	individual	NNS
cord-023443-pvz7dll9	391	13	are	be	VBP
cord-023443-pvz7dll9	391	14	reactive	reactive	JJ
cord-023443-pvz7dll9	391	15	to	to	IN
cord-023443-pvz7dll9	391	16	this	this	DT
cord-023443-pvz7dll9	391	17	protease	protease	NN
cord-023443-pvz7dll9	391	18	in	in	IN
cord-023443-pvz7dll9	391	19	standard	standard	JJ
cord-023443-pvz7dll9	391	20	assays	assay	NNS
cord-023443-pvz7dll9	391	21	for	for	IN
cord-023443-pvz7dll9	391	22	detection	detection	NN
cord-023443-pvz7dll9	391	23	of	of	IN
cord-023443-pvz7dll9	391	24	IgE.	ige.	NN
cord-023443-pvz7dll9	392	1	A	a	DT
cord-023443-pvz7dll9	392	2	curative	curative	JJ
cord-023443-pvz7dll9	392	3	treatment	treatment	NN
cord-023443-pvz7dll9	392	4	for	for	IN
cord-023443-pvz7dll9	392	5	atopic	atopic	JJ
cord-023443-pvz7dll9	392	6	allergy	allergy	NN
cord-023443-pvz7dll9	392	7	is	be	VBZ
cord-023443-pvz7dll9	392	8	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	392	9	(	(	-LRB-
cord-023443-pvz7dll9	392	10	IT	it	NN
cord-023443-pvz7dll9	392	11	)	)	-RRB-
cord-023443-pvz7dll9	392	12	with	with	IN
cord-023443-pvz7dll9	392	13	HDM	HDM	NNP
cord-023443-pvz7dll9	392	14	extracts	extract	NNS
cord-023443-pvz7dll9	392	15	which	which	WDT
cord-023443-pvz7dll9	392	16	are	be	VBP
cord-023443-pvz7dll9	392	17	complex	complex	JJ
cord-023443-pvz7dll9	392	18	mixtures	mixture	NNS
cord-023443-pvz7dll9	392	19	occasionally	occasionally	RB
cord-023443-pvz7dll9	392	20	resulting	result	VBG
cord-023443-pvz7dll9	392	21	in	in	IN
cord-023443-pvz7dll9	392	22	anaphylactic	anaphylactic	JJ
cord-023443-pvz7dll9	392	23	reactions	reaction	NNS
cord-023443-pvz7dll9	392	24	.	.	.
cord-023443-pvz7dll9	393	1	Novozymes	Novozymes	NNP
cord-023443-pvz7dll9	393	2	focuses	focus	VBZ
cord-023443-pvz7dll9	393	3	on	on	IN
cord-023443-pvz7dll9	393	4	developing	develop	VBG
cord-023443-pvz7dll9	393	5	a	a	DT
cord-023443-pvz7dll9	393	6	recombinant	recombinant	JJ
cord-023443-pvz7dll9	393	7	variant	variant	NN
cord-023443-pvz7dll9	393	8	of	of	IN
cord-023443-pvz7dll9	393	9	Der	Der	NNP
cord-023443-pvz7dll9	393	10	p1	p1	NNP
cord-023443-pvz7dll9	393	11	which	which	WDT
cord-023443-pvz7dll9	393	12	exhibit	exhibit	VBP
cord-023443-pvz7dll9	393	13	lowered	lower	VBD
cord-023443-pvz7dll9	393	14	risk	risk	NN
cord-023443-pvz7dll9	393	15	of	of	IN
cord-023443-pvz7dll9	393	16	IgE	IgE	NNP
cord-023443-pvz7dll9	393	17	-	-	HYPH
cord-023443-pvz7dll9	393	18	mediated	mediate	VBN
cord-023443-pvz7dll9	393	19	allergic	allergic	JJ
cord-023443-pvz7dll9	393	20	reactions	reaction	NNS
cord-023443-pvz7dll9	393	21	,	,	,
cord-023443-pvz7dll9	393	22	while	while	IN
cord-023443-pvz7dll9	393	23	maintaining	maintain	VBG
cord-023443-pvz7dll9	393	24	its	-PRON-	PRP$
cord-023443-pvz7dll9	393	25	ability	ability	NN
cord-023443-pvz7dll9	393	26	to	to	TO
cord-023443-pvz7dll9	393	27	trigger	trigger	VB
cord-023443-pvz7dll9	393	28	proper	proper	JJ
cord-023443-pvz7dll9	393	29	Th	th	JJ
cord-023443-pvz7dll9	393	30	-	-	HYPH
cord-023443-pvz7dll9	393	31	cell	cell	NN
cord-023443-pvz7dll9	393	32	responses	response	NNS
cord-023443-pvz7dll9	393	33	.	.	.
cord-023443-pvz7dll9	394	1	This	this	DT
cord-023443-pvz7dll9	394	2	may	may	MD
cord-023443-pvz7dll9	394	3	provide	provide	VB
cord-023443-pvz7dll9	394	4	a	a	DT
cord-023443-pvz7dll9	394	5	safer	safe	JJR
cord-023443-pvz7dll9	394	6	alternative	alternative	NN
cord-023443-pvz7dll9	394	7	for	for	IN
cord-023443-pvz7dll9	394	8	specific	specific	JJ
cord-023443-pvz7dll9	394	9	IT	it	NN
cord-023443-pvz7dll9	394	10	of	of	IN
cord-023443-pvz7dll9	394	11	HDM	HDM	NNP
cord-023443-pvz7dll9	394	12	allergy	allergy	NN
cord-023443-pvz7dll9	394	13	.	.	.
cord-023443-pvz7dll9	395	1	A	a	DT
cord-023443-pvz7dll9	395	2	secreted	secrete	VBN
cord-023443-pvz7dll9	395	3	recombinant	recombinant	JJ
cord-023443-pvz7dll9	395	4	form	form	NN
cord-023443-pvz7dll9	395	5	of	of	IN
cord-023443-pvz7dll9	395	6	pro	pro	JJ
cord-023443-pvz7dll9	395	7	-	-	JJ
cord-023443-pvz7dll9	395	8	Der	der	JJ
cord-023443-pvz7dll9	395	9	p	p	NN
cord-023443-pvz7dll9	395	10	1	1	CD
cord-023443-pvz7dll9	395	11	expressed	express	VBN
cord-023443-pvz7dll9	395	12	by	by	IN
cord-023443-pvz7dll9	395	13	Saccharamyces	Saccharamyces	NNP
cord-023443-pvz7dll9	395	14	cerevisiae	cerevisiae	NNS
cord-023443-pvz7dll9	395	15	was	be	VBD
cord-023443-pvz7dll9	395	16	obtained	obtain	VBN
cord-023443-pvz7dll9	395	17	by	by	IN
cord-023443-pvz7dll9	395	18	fusion	fusion	NN
cord-023443-pvz7dll9	395	19	of	of	IN
cord-023443-pvz7dll9	395	20	the	the	DT
cord-023443-pvz7dll9	395	21	pro	pro	JJ
cord-023443-pvz7dll9	395	22	-	-	JJ
cord-023443-pvz7dll9	395	23	enzyme	enzyme	JJ
cord-023443-pvz7dll9	395	24	to	to	IN
cord-023443-pvz7dll9	395	25	a	a	DT
cord-023443-pvz7dll9	395	26	fungal	fungal	JJ
cord-023443-pvz7dll9	395	27	signal	signal	NN
cord-023443-pvz7dll9	395	28	peptide	peptide	NN
cord-023443-pvz7dll9	395	29	.	.	.
cord-023443-pvz7dll9	396	1	The	the	DT
cord-023443-pvz7dll9	396	2	N	n	CD
cord-023443-pvz7dll9	396	3	-	-	HYPH
cord-023443-pvz7dll9	396	4	glycosylation	glycosylation	NN
cord-023443-pvz7dll9	396	5	site	site	NN
cord-023443-pvz7dll9	396	6	of	of	IN
cord-023443-pvz7dll9	396	7	Der	Der	NNP
cord-023443-pvz7dll9	396	8	p1	p1	NNP
cord-023443-pvz7dll9	396	9	was	be	VBD
cord-023443-pvz7dll9	396	10	mutated	mutate	VBN
cord-023443-pvz7dll9	396	11	resulting	result	VBG
cord-023443-pvz7dll9	396	12	in	in	IN
cord-023443-pvz7dll9	396	13	a	a	DT
cord-023443-pvz7dll9	396	14	deglycosylated	deglycosylated	JJ
cord-023443-pvz7dll9	396	15	pro	pro	JJ
cord-023443-pvz7dll9	396	16	-	-	JJ
cord-023443-pvz7dll9	396	17	enzyme	enzyme	JJ
cord-023443-pvz7dll9	396	18	with	with	IN
cord-023443-pvz7dll9	396	19	a	a	DT
cord-023443-pvz7dll9	396	20	molecular	molecular	JJ
cord-023443-pvz7dll9	396	21	mass	mass	NN
cord-023443-pvz7dll9	396	22	of	of	IN
cord-023443-pvz7dll9	396	23	35	35	CD
cord-023443-pvz7dll9	396	24	kDa	kDa	NNS
cord-023443-pvz7dll9	396	25	.	.	.
cord-023443-pvz7dll9	397	1	Protein	protein	NN
cord-023443-pvz7dll9	397	2	purification	purification	NN
cord-023443-pvz7dll9	397	3	procedure	procedure	NN
cord-023443-pvz7dll9	397	4	was	be	VBD
cord-023443-pvz7dll9	397	5	developed	develop	VBN
cord-023443-pvz7dll9	397	6	to	to	TO
cord-023443-pvz7dll9	397	7	obtain	obtain	VB
cord-023443-pvz7dll9	397	8	nearly	nearly	RB
cord-023443-pvz7dll9	397	9	pure	pure	JJ
cord-023443-pvz7dll9	397	10	Der	Der	NNP
cord-023443-pvz7dll9	397	11	p1	p1	NNP
cord-023443-pvz7dll9	397	12	protein	protein	NN
cord-023443-pvz7dll9	397	13	followed	follow	VBN
cord-023443-pvz7dll9	397	14	by	by	IN
cord-023443-pvz7dll9	397	15	determination	determination	NN
cord-023443-pvz7dll9	397	16	of	of	IN
cord-023443-pvz7dll9	397	17	concentration	concentration	NN
cord-023443-pvz7dll9	397	18	by	by	IN
cord-023443-pvz7dll9	397	19	active	active	JJ
cord-023443-pvz7dll9	397	20	-	-	HYPH
cord-023443-pvz7dll9	397	21	site	site	NN
cord-023443-pvz7dll9	397	22	-	-	HYPH
cord-023443-pvz7dll9	397	23	titration	titration	NN
cord-023443-pvz7dll9	397	24	with	with	IN
cord-023443-pvz7dll9	397	25	the	the	DT
cord-023443-pvz7dll9	397	26	cysteine	cysteine	NN
cord-023443-pvz7dll9	397	27	protease	protease	NN
cord-023443-pvz7dll9	397	28	inhibitor	inhibitor	NN
cord-023443-pvz7dll9	397	29	E64	E64	NNP
cord-023443-pvz7dll9	397	30	.	.	.
cord-023443-pvz7dll9	398	1	The	the	DT
cord-023443-pvz7dll9	398	2	deglycosylated	deglycosylated	JJ
cord-023443-pvz7dll9	398	3	recombinant	recombinant	JJ
cord-023443-pvz7dll9	398	4	pro	pro	JJ
cord-023443-pvz7dll9	398	5	-	-	JJ
cord-023443-pvz7dll9	398	6	Der	der	JJ
cord-023443-pvz7dll9	398	7	p	p	NN
cord-023443-pvz7dll9	398	8	1	1	CD
cord-023443-pvz7dll9	398	9	revealed	reveal	VBD
cord-023443-pvz7dll9	398	10	immunologic	immunologic	JJ
cord-023443-pvz7dll9	398	11	similarity	similarity	NN
cord-023443-pvz7dll9	398	12	to	to	IN
cord-023443-pvz7dll9	398	13	the	the	DT
cord-023443-pvz7dll9	398	14	native	native	JJ
cord-023443-pvz7dll9	398	15	Der	Der	NNP
cord-023443-pvz7dll9	398	16	p	p	NN
cord-023443-pvz7dll9	398	17	1	1	CD
cord-023443-pvz7dll9	398	18	molecule	molecule	NN
cord-023443-pvz7dll9	398	19	when	when	WRB
cord-023443-pvz7dll9	398	20	compared	compare	VBN
cord-023443-pvz7dll9	398	21	in	in	IN
cord-023443-pvz7dll9	398	22	basophile	basophile	JJ
cord-023443-pvz7dll9	398	23	histamine	histamine	NN
cord-023443-pvz7dll9	398	24	release	release	NN
cord-023443-pvz7dll9	398	25	,	,	,
cord-023443-pvz7dll9	398	26	IgE	ige	NN
cord-023443-pvz7dll9	398	27	-	-	HYPH
cord-023443-pvz7dll9	398	28	binding	bind	VBG
cord-023443-pvz7dll9	398	29	assays	assay	NNS
cord-023443-pvz7dll9	398	30	and	and	CC
cord-023443-pvz7dll9	398	31	T	t	NN
cord-023443-pvz7dll9	398	32	-	-	HYPH
cord-023443-pvz7dll9	398	33	cell	cell	NN
cord-023443-pvz7dll9	398	34	proliferation	proliferation	NN
cord-023443-pvz7dll9	398	35	assays	assay	NNS
cord-023443-pvz7dll9	398	36	.	.	.
cord-023443-pvz7dll9	399	1	By	by	IN
cord-023443-pvz7dll9	399	2	in	in	IN
cord-023443-pvz7dll9	399	3	silico	silico	NN
cord-023443-pvz7dll9	399	4	epitope	epitope	NN
cord-023443-pvz7dll9	399	5	mapping	mapping	NN
cord-023443-pvz7dll9	399	6	of	of	IN
cord-023443-pvz7dll9	399	7	a	a	DT
cord-023443-pvz7dll9	399	8	modelled	model	VBN
cord-023443-pvz7dll9	399	9	3-dimensional	3-dimensional	JJ
cord-023443-pvz7dll9	399	10	structure	structure	NN
cord-023443-pvz7dll9	399	11	of	of	IN
cord-023443-pvz7dll9	399	12	Der	Der	NNP
cord-023443-pvz7dll9	399	13	p1	p1	NNP
cord-023443-pvz7dll9	399	14	,	,	,
cord-023443-pvz7dll9	399	15	five	five	CD
cord-023443-pvz7dll9	399	16	putative	putative	JJ
cord-023443-pvz7dll9	399	17	IgG	IgG	NNP
cord-023443-pvz7dll9	399	18	and	and	CC
cord-023443-pvz7dll9	399	19	IgE	IgE	NNP
cord-023443-pvz7dll9	399	20	epitopes	epitope	NNS
cord-023443-pvz7dll9	399	21	were	be	VBD
cord-023443-pvz7dll9	399	22	predicted	predict	VBN
cord-023443-pvz7dll9	399	23	.	.	.
cord-023443-pvz7dll9	400	1	By	by	IN
cord-023443-pvz7dll9	400	2	protein	protein	NN
cord-023443-pvz7dll9	400	3	engineering	engineering	NN
cord-023443-pvz7dll9	400	4	,	,	,
cord-023443-pvz7dll9	400	5	the	the	DT
cord-023443-pvz7dll9	400	6	predicted	predict	VBN
cord-023443-pvz7dll9	400	7	epitopes	epitope	NNS
cord-023443-pvz7dll9	400	8	were	be	VBD
cord-023443-pvz7dll9	400	9	removed	remove	VBN
cord-023443-pvz7dll9	400	10	one	one	CD
cord-023443-pvz7dll9	400	11	by	by	IN
cord-023443-pvz7dll9	400	12	one	one	CD
cord-023443-pvz7dll9	400	13	in	in	IN
cord-023443-pvz7dll9	400	14	Der	Der	NNP
cord-023443-pvz7dll9	400	15	p1	p1	NN
cord-023443-pvz7dll9	400	16	and	and	CC
cord-023443-pvz7dll9	400	17	screening	screening	NN
cord-023443-pvz7dll9	400	18	for	for	IN
cord-023443-pvz7dll9	400	19	hypoallergenic	hypoallergenic	JJ
cord-023443-pvz7dll9	400	20	variants	variant	NNS
cord-023443-pvz7dll9	400	21	was	be	VBD
cord-023443-pvz7dll9	400	22	performed	perform	VBN
cord-023443-pvz7dll9	400	23	.	.	.
cord-023443-pvz7dll9	401	1	Combining	combine	VBG
cord-023443-pvz7dll9	401	2	inhaled	inhale	VBN
cord-023443-pvz7dll9	401	3	long	long	RB
cord-023443-pvz7dll9	401	4	-	-	HYPH
cord-023443-pvz7dll9	401	5	acting	act	VBG
cord-023443-pvz7dll9	401	6	b-2	b-2	NN
cord-023443-pvz7dll9	401	7	agonist	agonist	NN
cord-023443-pvz7dll9	401	8	(	(	-LRB-
cord-023443-pvz7dll9	401	9	LABA	LABA	NNP
cord-023443-pvz7dll9	401	10	)	)	-RRB-
cord-023443-pvz7dll9	401	11	and	and	CC
cord-023443-pvz7dll9	401	12	inhaled	inhale	VBN
cord-023443-pvz7dll9	401	13	corticosteroid	corticosteroid	NNP
cord-023443-pvz7dll9	401	14	(	(	-LRB-
cord-023443-pvz7dll9	401	15	ICS	ICS	NNP
cord-023443-pvz7dll9	401	16	)	)	-RRB-
cord-023443-pvz7dll9	401	17	seems	seem	VBZ
cord-023443-pvz7dll9	401	18	to	to	TO
cord-023443-pvz7dll9	401	19	offer	offer	VB
cord-023443-pvz7dll9	401	20	asthma	asthma	NN
cord-023443-pvz7dll9	401	21	control	control	NN
cord-023443-pvz7dll9	401	22	at	at	IN
cord-023443-pvz7dll9	401	23	a	a	DT
cord-023443-pvz7dll9	401	24	lower	low	JJR
cord-023443-pvz7dll9	401	25	dose	dose	NN
cord-023443-pvz7dll9	401	26	of	of	IN
cord-023443-pvz7dll9	401	27	ICS	ICS	NNP
cord-023443-pvz7dll9	401	28	than	than	IN
cord-023443-pvz7dll9	401	29	achieved	achieve	VBN
cord-023443-pvz7dll9	401	30	by	by	IN
cord-023443-pvz7dll9	401	31	ICS	ICS	NNP
cord-023443-pvz7dll9	401	32	alone	alone	JJ
cord-023443-pvz7dll9	401	33	.	.	.
cord-023443-pvz7dll9	402	1	Fine	fine	JJ
cord-023443-pvz7dll9	402	2	mapping	mapping	NN
cord-023443-pvz7dll9	402	3	of	of	IN
cord-023443-pvz7dll9	402	4	T	t	NN
cord-023443-pvz7dll9	402	5	-	-	HYPH
cord-023443-pvz7dll9	402	6	cell	cell	NN
cord-023443-pvz7dll9	402	7	surface	surface	NN
cord-023443-pvz7dll9	402	8	markers	marker	NNS
cord-023443-pvz7dll9	402	9	by	by	IN
cord-023443-pvz7dll9	402	10	flow	flow	NN
cord-023443-pvz7dll9	402	11	cytometry	cytometry	NN
cord-023443-pvz7dll9	402	12	offers	offer	VBZ
cord-023443-pvz7dll9	402	13	a	a	DT
cord-023443-pvz7dll9	402	14	detailed	detailed	JJ
cord-023443-pvz7dll9	402	15	status	status	NN
cord-023443-pvz7dll9	402	16	of	of	IN
cord-023443-pvz7dll9	402	17	the	the	DT
cord-023443-pvz7dll9	402	18	individual	individual	NN
cord-023443-pvz7dll9	402	19	's	's	POS
cord-023443-pvz7dll9	402	20	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	402	21	response	response	NN
cord-023443-pvz7dll9	402	22	.	.	.
cord-023443-pvz7dll9	403	1	The	the	DT
cord-023443-pvz7dll9	403	2	frequency	frequency	NN
cord-023443-pvz7dll9	403	3	of	of	IN
cord-023443-pvz7dll9	403	4	MT2	mt2	NN
cord-023443-pvz7dll9	403	5	(	(	-LRB-
cord-023443-pvz7dll9	403	6	CD4	CD4	NNP
cord-023443-pvz7dll9	403	7	þ	þ	NNP
cord-023443-pvz7dll9	403	8	CD45RA	cd45ra	NN
cord-023443-pvz7dll9	403	9	-CD62L	-CD62L	NNP
cord-023443-pvz7dll9	403	10	þ	þ	CD
cord-023443-pvz7dll9	403	11	CD11adim	CD11adim	NNPS
cord-023443-pvz7dll9	403	12	)	)	-RRB-
cord-023443-pvz7dll9	403	13	and	and	CC
cord-023443-pvz7dll9	403	14	MT1	MT1	NNP
cord-023443-pvz7dll9	403	15	(	(	-LRB-
cord-023443-pvz7dll9	403	16	CD4	CD4	NNP
cord-023443-pvz7dll9	403	17	þ	þ	NNP
cord-023443-pvz7dll9	403	18	CD45RA	cd45ra	NN
cord-023443-pvz7dll9	403	19	-CD62L	-CD62L	NNP
cord-023443-pvz7dll9	403	20	-CD11abright	-CD11abright	NFP
cord-023443-pvz7dll9	403	21	)	)	-RRB-
cord-023443-pvz7dll9	403	22	cells	cell	NNS
cord-023443-pvz7dll9	403	23	in	in	IN
cord-023443-pvz7dll9	403	24	peripheral	peripheral	JJ
cord-023443-pvz7dll9	403	25	blood	blood	NN
cord-023443-pvz7dll9	403	26	,	,	,
cord-023443-pvz7dll9	403	27	and	and	CC
cord-023443-pvz7dll9	403	28	their	-PRON-	PRP$
cord-023443-pvz7dll9	403	29	ratio	ratio	NN
cord-023443-pvz7dll9	403	30	,	,	,
cord-023443-pvz7dll9	403	31	has	have	VBZ
cord-023443-pvz7dll9	403	32	been	be	VBN
cord-023443-pvz7dll9	403	33	shown	show	VBN
cord-023443-pvz7dll9	403	34	to	to	TO
cord-023443-pvz7dll9	403	35	differ	differ	VB
cord-023443-pvz7dll9	403	36	predictably	predictably	RB
cord-023443-pvz7dll9	403	37	in	in	IN
cord-023443-pvz7dll9	403	38	atopics	atopic	NNS
cord-023443-pvz7dll9	403	39	and	and	CC
cord-023443-pvz7dll9	403	40	patients	patient	NNS
cord-023443-pvz7dll9	403	41	with	with	IN
cord-023443-pvz7dll9	403	42	leprosy	leprosy	NN
cord-023443-pvz7dll9	403	43	,	,	,
cord-023443-pvz7dll9	403	44	where	where	WRB
cord-023443-pvz7dll9	403	45	MT2	MT2	NNP
cord-023443-pvz7dll9	403	46	correlates	correlate	VBZ
cord-023443-pvz7dll9	403	47	with	with	IN
cord-023443-pvz7dll9	403	48	a	a	DT
cord-023443-pvz7dll9	403	49	Th2	th2	CD
cord-023443-pvz7dll9	403	50	phenotype	phenotype	NN
cord-023443-pvz7dll9	403	51	and	and	CC
cord-023443-pvz7dll9	403	52	MT1	MT1	NNP
cord-023443-pvz7dll9	403	53	with	with	IN
cord-023443-pvz7dll9	403	54	a	a	DT
cord-023443-pvz7dll9	403	55	Th1	th1	CD
cord-023443-pvz7dll9	403	56	phenotype	phenotype	NN
cord-023443-pvz7dll9	403	57	.	.	.
cord-023443-pvz7dll9	404	1	Stable	stable	JJ
cord-023443-pvz7dll9	404	2	asthmatics	asthmatic	NNS
cord-023443-pvz7dll9	404	3	,	,	,
cord-023443-pvz7dll9	404	4	requiring	require	VBG
cord-023443-pvz7dll9	404	5	fluticasone	fluticasone	NN
cord-023443-pvz7dll9	404	6	propionate	propionate	NN
cord-023443-pvz7dll9	404	7	(	(	-LRB-
cord-023443-pvz7dll9	404	8	FP	FP	NNP
cord-023443-pvz7dll9	404	9	)	)	-RRB-
cord-023443-pvz7dll9	404	10	750	750	CD
cord-023443-pvz7dll9	404	11	-	-	HYPH
cord-023443-pvz7dll9	404	12	1000	1000	CD
cord-023443-pvz7dll9	404	13	mg	mg	NNP
cord-023443-pvz7dll9	404	14	daily	daily	JJ
cord-023443-pvz7dll9	404	15	or	or	CC
cord-023443-pvz7dll9	404	16	equivalent	equivalent	JJ
cord-023443-pvz7dll9	404	17	,	,	,
cord-023443-pvz7dll9	404	18	were	be	VBD
cord-023443-pvz7dll9	404	19	randomized	randomize	VBN
cord-023443-pvz7dll9	404	20	to	to	TO
cord-023443-pvz7dll9	404	21	receive	receive	VB
cord-023443-pvz7dll9	404	22	,	,	,
cord-023443-pvz7dll9	404	23	double	double	JJ
cord-023443-pvz7dll9	404	24	-	-	HYPH
cord-023443-pvz7dll9	404	25	blinded	blinded	JJ
cord-023443-pvz7dll9	404	26	,	,	,
cord-023443-pvz7dll9	405	1	either	either	CC
cord-023443-pvz7dll9	405	2	Seretide	Seretide	NNP
cord-023443-pvz7dll9	405	3	1	1	CD
cord-023443-pvz7dll9	405	4	[	[	-LRB-
cord-023443-pvz7dll9	405	5	salmeterol	salmeterol	NN
cord-023443-pvz7dll9	405	6	and	and	CC
cord-023443-pvz7dll9	405	7	fluticasone	fluticasone	NN
cord-023443-pvz7dll9	405	8	propionate	propionate	NNP
cord-023443-pvz7dll9	405	9	(	(	-LRB-
cord-023443-pvz7dll9	405	10	SFC	SFC	NNP
cord-023443-pvz7dll9	405	11	,	,	,
cord-023443-pvz7dll9	405	12	n	n	NN
cord-023443-pvz7dll9	405	13	¼	¼	NNP
cord-023443-pvz7dll9	405	14	16	16	CD
cord-023443-pvz7dll9	405	15	)	)	-RRB-
cord-023443-pvz7dll9	405	16	]	]	-RRB-
cord-023443-pvz7dll9	406	1	50	50	CD
cord-023443-pvz7dll9	406	2	mg/500	mg/500	NNS
cord-023443-pvz7dll9	406	3	mg	mg	NNP
cord-023443-pvz7dll9	406	4	bd	bd	NNP
cord-023443-pvz7dll9	406	5	or	or	CC
cord-023443-pvz7dll9	406	6	FP	FP	NNP
cord-023443-pvz7dll9	407	1	500	500	CD
cord-023443-pvz7dll9	407	2	mg	mg	NNP
cord-023443-pvz7dll9	407	3	bd	bd	NNP
cord-023443-pvz7dll9	407	4	(	(	-LRB-
cord-023443-pvz7dll9	407	5	n	n	NNP
cord-023443-pvz7dll9	407	6	¼	¼	NNP
cord-023443-pvz7dll9	407	7	17	17	CD
cord-023443-pvz7dll9	407	8	)	)	-RRB-
cord-023443-pvz7dll9	407	9	.	.	.
cord-023443-pvz7dll9	408	1	If	if	IN
cord-023443-pvz7dll9	408	2	asthma	asthma	NN
cord-023443-pvz7dll9	408	3	was	be	VBD
cord-023443-pvz7dll9	408	4	controlled	control	VBN
cord-023443-pvz7dll9	408	5	based	base	VBN
cord-023443-pvz7dll9	408	6	on	on	IN
cord-023443-pvz7dll9	408	7	lung	lung	NN
cord-023443-pvz7dll9	408	8	function	function	NN
cord-023443-pvz7dll9	408	9	and	and	CC
cord-023443-pvz7dll9	408	10	symptoms	symptom	NNS
cord-023443-pvz7dll9	408	11	at	at	IN
cord-023443-pvz7dll9	408	12	clinic	clinic	NN
cord-023443-pvz7dll9	408	13	visits	visit	VBZ
cord-023443-pvz7dll9	408	14	every	every	DT
cord-023443-pvz7dll9	408	15	6	6	CD
cord-023443-pvz7dll9	408	16	weeks	week	NNS
cord-023443-pvz7dll9	408	17	,	,	,
cord-023443-pvz7dll9	408	18	ICS	ICS	NNP
cord-023443-pvz7dll9	408	19	dose	dose	NN
cord-023443-pvz7dll9	408	20	was	be	VBD
cord-023443-pvz7dll9	408	21	tapered	taper	VBN
cord-023443-pvz7dll9	408	22	until	until	IN
cord-023443-pvz7dll9	408	23	asthma	asthma	NN
cord-023443-pvz7dll9	408	24	exacerbated	exacerbate	VBD
cord-023443-pvz7dll9	408	25	or	or	CC
cord-023443-pvz7dll9	408	26	0	0	NFP
cord-023443-pvz7dll9	408	27	mg	mg	NN
cord-023443-pvz7dll9	408	28	was	be	VBD
cord-023443-pvz7dll9	408	29	reached	reach	VBN
cord-023443-pvz7dll9	408	30	.	.	.
cord-023443-pvz7dll9	409	1	The	the	DT
cord-023443-pvz7dll9	409	2	frequency	frequency	NN
cord-023443-pvz7dll9	409	3	and	and	CC
cord-023443-pvz7dll9	409	4	ratio	ratio	NN
cord-023443-pvz7dll9	409	5	of	of	IN
cord-023443-pvz7dll9	409	6	MT2	MT2	NNP
cord-023443-pvz7dll9	409	7	and	and	CC
cord-023443-pvz7dll9	409	8	MT1	MT1	NNP
cord-023443-pvz7dll9	409	9	T	T	NNP
cord-023443-pvz7dll9	409	10	cells	cell	NNS
cord-023443-pvz7dll9	409	11	of	of	IN
cord-023443-pvz7dll9	409	12	the	the	DT
cord-023443-pvz7dll9	409	13	patients	patient	NNS
cord-023443-pvz7dll9	409	14	was	be	VBD
cord-023443-pvz7dll9	409	15	monitored	monitor	VBN
cord-023443-pvz7dll9	409	16	at	at	IN
cord-023443-pvz7dll9	409	17	6	6	CD
cord-023443-pvz7dll9	409	18	week	week	NN
cord-023443-pvz7dll9	409	19	intervals	interval	NNS
cord-023443-pvz7dll9	409	20	.	.	.
cord-023443-pvz7dll9	410	1	As	as	IN
cord-023443-pvz7dll9	410	2	treatment	treatment	NN
cord-023443-pvz7dll9	410	3	tapered	taper	VBN
cord-023443-pvz7dll9	410	4	,	,	,
cord-023443-pvz7dll9	410	5	the	the	DT
cord-023443-pvz7dll9	410	6	frequency	frequency	NN
cord-023443-pvz7dll9	410	7	of	of	IN
cord-023443-pvz7dll9	410	8	MT2	mt2	NN
cord-023443-pvz7dll9	410	9	cells	cell	NNS
cord-023443-pvz7dll9	410	10	decreased	decrease	VBD
cord-023443-pvz7dll9	410	11	(	(	-LRB-
cord-023443-pvz7dll9	410	12	P	p	NN
cord-023443-pvz7dll9	410	13	¼	¼	CD
cord-023443-pvz7dll9	410	14	0038	0038	CD
cord-023443-pvz7dll9	410	15	from	from	IN
cord-023443-pvz7dll9	410	16	first	first	JJ
cord-023443-pvz7dll9	410	17	to	to	IN
cord-023443-pvz7dll9	410	18	final	final	JJ
cord-023443-pvz7dll9	410	19	visit	visit	NN
cord-023443-pvz7dll9	410	20	)	)	-RRB-
cord-023443-pvz7dll9	410	21	,	,	,
cord-023443-pvz7dll9	410	22	whereas	whereas	IN
cord-023443-pvz7dll9	410	23	that	that	DT
cord-023443-pvz7dll9	410	24	of	of	IN
cord-023443-pvz7dll9	410	25	MT1	MT1	NNP
cord-023443-pvz7dll9	410	26	cells	cell	NNS
cord-023443-pvz7dll9	410	27	increased	increase	VBD
cord-023443-pvz7dll9	410	28	.	.	.
cord-023443-pvz7dll9	411	1	The	the	DT
cord-023443-pvz7dll9	411	2	ratio	ratio	NN
cord-023443-pvz7dll9	411	3	of	of	IN
cord-023443-pvz7dll9	411	4	MT2	MT2	NNP
cord-023443-pvz7dll9	411	5	/	/	SYM
cord-023443-pvz7dll9	411	6	MT1	MT1	NNP
cord-023443-pvz7dll9	411	7	decreased	decrease	VBD
cord-023443-pvz7dll9	411	8	(	(	-LRB-
cord-023443-pvz7dll9	411	9	P	p	NN
cord-023443-pvz7dll9	411	10	¼	¼	CD
cord-023443-pvz7dll9	411	11	0049	0049	CD
cord-023443-pvz7dll9	411	12	from	from	IN
cord-023443-pvz7dll9	411	13	first	first	JJ
cord-023443-pvz7dll9	411	14	to	to	IN
cord-023443-pvz7dll9	411	15	final	final	JJ
cord-023443-pvz7dll9	411	16	visit	visit	NN
cord-023443-pvz7dll9	411	17	)	)	-RRB-
cord-023443-pvz7dll9	411	18	.	.	.
cord-023443-pvz7dll9	412	1	In	in	IN
cord-023443-pvz7dll9	412	2	patients	patient	NNS
cord-023443-pvz7dll9	412	3	receiving	receive	VBG
cord-023443-pvz7dll9	412	4	LABA	LABA	NNP
cord-023443-pvz7dll9	412	5	þ	þ	NNP
cord-023443-pvz7dll9	412	6	ICS	ICS	NNP
cord-023443-pvz7dll9	412	7	,	,	,
cord-023443-pvz7dll9	412	8	the	the	DT
cord-023443-pvz7dll9	412	9	fall	fall	NN
cord-023443-pvz7dll9	412	10	in	in	IN
cord-023443-pvz7dll9	412	11	MT2	MT2	NNP
cord-023443-pvz7dll9	412	12	/	/	SYM
cord-023443-pvz7dll9	412	13	MT1	MT1	NNP
cord-023443-pvz7dll9	412	14	ratio	ratio	NN
cord-023443-pvz7dll9	412	15	appeared	appear	VBD
cord-023443-pvz7dll9	412	16	to	to	TO
cord-023443-pvz7dll9	412	17	be	be	VB
cord-023443-pvz7dll9	412	18	more	more	RBR
cord-023443-pvz7dll9	412	19	pronounced	pronounced	JJ
cord-023443-pvz7dll9	412	20	than	than	IN
cord-023443-pvz7dll9	412	21	in	in	IN
cord-023443-pvz7dll9	412	22	patients	patient	NNS
cord-023443-pvz7dll9	412	23	receiving	receive	VBG
cord-023443-pvz7dll9	412	24	ICS	ICS	NNP
cord-023443-pvz7dll9	412	25	alone	alone	JJ
cord-023443-pvz7dll9	412	26	.	.	.
cord-023443-pvz7dll9	413	1	Thus	thus	RB
cord-023443-pvz7dll9	413	2	,	,	,
cord-023443-pvz7dll9	413	3	the	the	DT
cord-023443-pvz7dll9	413	4	MT2	mt2	NN
cord-023443-pvz7dll9	413	5	phenotype	phenotype	NN
cord-023443-pvz7dll9	413	6	may	may	MD
cord-023443-pvz7dll9	413	7	be	be	VB
cord-023443-pvz7dll9	413	8	associated	associate	VBN
cord-023443-pvz7dll9	413	9	with	with	IN
cord-023443-pvz7dll9	413	10	stable	stable	JJ
cord-023443-pvz7dll9	413	11	asthma	asthma	NN
cord-023443-pvz7dll9	413	12	,	,	,
cord-023443-pvz7dll9	413	13	whereas	whereas	IN
cord-023443-pvz7dll9	413	14	an	an	DT
cord-023443-pvz7dll9	413	15	imminent	imminent	JJ
cord-023443-pvz7dll9	413	16	exacerbation	exacerbation	NN
cord-023443-pvz7dll9	413	17	may	may	MD
cord-023443-pvz7dll9	413	18	associate	associate	VB
cord-023443-pvz7dll9	413	19	with	with	IN
cord-023443-pvz7dll9	413	20	an	an	DT
cord-023443-pvz7dll9	413	21	increase	increase	NN
cord-023443-pvz7dll9	413	22	in	in	IN
cord-023443-pvz7dll9	413	23	the	the	DT
cord-023443-pvz7dll9	413	24	MT1	MT1	NNP
cord-023443-pvz7dll9	413	25	phenotype	phenotype	NN
cord-023443-pvz7dll9	413	26	.	.	.
cord-023443-pvz7dll9	414	1	LABA	LABA	NNP
cord-023443-pvz7dll9	414	2	may	may	MD
cord-023443-pvz7dll9	414	3	allow	allow	VB
cord-023443-pvz7dll9	414	4	for	for	IN
cord-023443-pvz7dll9	414	5	a	a	DT
cord-023443-pvz7dll9	414	6	greater	great	JJR
cord-023443-pvz7dll9	414	7	effect	effect	NN
cord-023443-pvz7dll9	414	8	of	of	IN
cord-023443-pvz7dll9	414	9	FP	FP	NNP
cord-023443-pvz7dll9	414	10	on	on	IN
cord-023443-pvz7dll9	414	11	the	the	DT
cord-023443-pvz7dll9	414	12	MT	MT	NNP
cord-023443-pvz7dll9	414	13	ratio	ratio	NN
cord-023443-pvz7dll9	414	14	.	.	.
cord-023443-pvz7dll9	415	1	Activation	activation	NN
cord-023443-pvz7dll9	415	2	of	of	IN
cord-023443-pvz7dll9	415	3	complement	complement	JJ
cord-023443-pvz7dll9	415	4	pathways	pathway	NNS
cord-023443-pvz7dll9	415	5	,	,	,
cord-023443-pvz7dll9	415	6	leading	lead	VBG
cord-023443-pvz7dll9	415	7	to	to	IN
cord-023443-pvz7dll9	415	8	production	production	NN
cord-023443-pvz7dll9	415	9	of	of	IN
cord-023443-pvz7dll9	415	10	C3a	C3a	NNP
cord-023443-pvz7dll9	415	11	and	and	CC
cord-023443-pvz7dll9	415	12	C5a	C5a	NNP
cord-023443-pvz7dll9	415	13	anaphylatoxins	anaphylatoxin	NNS
cord-023443-pvz7dll9	415	14	,	,	,
cord-023443-pvz7dll9	415	15	has	have	VBZ
cord-023443-pvz7dll9	415	16	been	be	VBN
cord-023443-pvz7dll9	415	17	postulated	postulate	VBN
cord-023443-pvz7dll9	415	18	in	in	IN
cord-023443-pvz7dll9	415	19	the	the	DT
cord-023443-pvz7dll9	415	20	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	415	21	of	of	IN
cord-023443-pvz7dll9	415	22	asthma	asthma	NN
cord-023443-pvz7dll9	415	23	and	and	CC
cord-023443-pvz7dll9	415	24	allergic	allergic	JJ
cord-023443-pvz7dll9	415	25	airway	airway	NN
cord-023443-pvz7dll9	415	26	inflammation	inflammation	NN
cord-023443-pvz7dll9	415	27	.	.	.
cord-023443-pvz7dll9	416	1	The	the	DT
cord-023443-pvz7dll9	416	2	present	present	JJ
cord-023443-pvz7dll9	416	3	study	study	NN
cord-023443-pvz7dll9	416	4	was	be	VBD
cord-023443-pvz7dll9	416	5	undertaken	undertake	VBN
cord-023443-pvz7dll9	416	6	to	to	TO
cord-023443-pvz7dll9	416	7	investigate	investigate	VB
cord-023443-pvz7dll9	416	8	the	the	DT
cord-023443-pvz7dll9	416	9	role	role	NN
cord-023443-pvz7dll9	416	10	of	of	IN
cord-023443-pvz7dll9	416	11	mannan	mannan	NNP
cord-023443-pvz7dll9	416	12	-	-	HYPH
cord-023443-pvz7dll9	416	13	binding	bind	VBG
cord-023443-pvz7dll9	416	14	lectin	lectin	NN
cord-023443-pvz7dll9	416	15	(	(	-LRB-
cord-023443-pvz7dll9	416	16	MBL	MBL	NNP
cord-023443-pvz7dll9	416	17	)	)	-RRB-
cord-023443-pvz7dll9	416	18	,	,	,
cord-023443-pvz7dll9	416	19	an	an	DT
cord-023443-pvz7dll9	416	20	initiator	initiator	NN
cord-023443-pvz7dll9	416	21	of	of	IN
cord-023443-pvz7dll9	416	22	the	the	DT
cord-023443-pvz7dll9	416	23	lectin	lectin	NN
cord-023443-pvz7dll9	416	24	pathway	pathway	NN
cord-023443-pvz7dll9	416	25	of	of	IN
cord-023443-pvz7dll9	416	26	complement	complement	NN
cord-023443-pvz7dll9	416	27	,	,	,
cord-023443-pvz7dll9	416	28	in	in	IN
cord-023443-pvz7dll9	416	29	asthma	asthma	NN
cord-023443-pvz7dll9	416	30	and	and	CC
cord-023443-pvz7dll9	416	31	allergic	allergic	JJ
cord-023443-pvz7dll9	416	32	rhinitis	rhinitis	NN
cord-023443-pvz7dll9	416	33	.	.	.
cord-023443-pvz7dll9	417	1	MBL	MBL	NNP
cord-023443-pvz7dll9	417	2	levels	level	NNS
cord-023443-pvz7dll9	417	3	and	and	CC
cord-023443-pvz7dll9	417	4	MBL	mbl	NN
cord-023443-pvz7dll9	417	5	-	-	HYPH
cord-023443-pvz7dll9	417	6	induced	induce	VBN
cord-023443-pvz7dll9	417	7	complement	complement	NN
cord-023443-pvz7dll9	417	8	activity	activity	NN
cord-023443-pvz7dll9	417	9	were	be	VBD
cord-023443-pvz7dll9	417	10	determined	determine	VBN
cord-023443-pvz7dll9	417	11	in	in	IN
cord-023443-pvz7dll9	417	12	19	19	CD
cord-023443-pvz7dll9	417	13	patients	patient	NNS
cord-023443-pvz7dll9	417	14	of	of	IN
cord-023443-pvz7dll9	417	15	bronchial	bronchial	JJ
cord-023443-pvz7dll9	417	16	asthma	asthma	NN
cord-023443-pvz7dll9	417	17	with	with	IN
cord-023443-pvz7dll9	417	18	allergic	allergic	JJ
cord-023443-pvz7dll9	417	19	rhinitis	rhinitis	NN
cord-023443-pvz7dll9	417	20	and	and	CC
cord-023443-pvz7dll9	417	21	20	20	CD
cord-023443-pvz7dll9	417	22	unrelated	unrelated	JJ
cord-023443-pvz7dll9	417	23	,	,	,
cord-023443-pvz7dll9	417	24	age	age	NN
cord-023443-pvz7dll9	417	25	-	-	HYPH
cord-023443-pvz7dll9	417	26	matched	match	VBN
cord-023443-pvz7dll9	417	27	controls	control	NNS
cord-023443-pvz7dll9	417	28	of	of	IN
cord-023443-pvz7dll9	417	29	Indian	indian	JJ
cord-023443-pvz7dll9	417	30	origin	origin	NN
cord-023443-pvz7dll9	417	31	.	.	.
cord-023443-pvz7dll9	418	1	MBL	MBL	NNP
cord-023443-pvz7dll9	418	2	levels	level	NNS
cord-023443-pvz7dll9	418	3	and	and	CC
cord-023443-pvz7dll9	418	4	activity	activity	NN
cord-023443-pvz7dll9	418	5	were	be	VBD
cord-023443-pvz7dll9	418	6	correlated	correlate	VBN
cord-023443-pvz7dll9	418	7	with	with	IN
cord-023443-pvz7dll9	418	8	percent	percent	NN
cord-023443-pvz7dll9	418	9	eosinophilia	eosinophilia	NN
cord-023443-pvz7dll9	418	10	and	and	CC
cord-023443-pvz7dll9	418	11	percent	percent	NN
cord-023443-pvz7dll9	418	12	predicted	predict	VBD
cord-023443-pvz7dll9	418	13	FEV1	FEV1	NNP
cord-023443-pvz7dll9	418	14	values	value	NNS
cord-023443-pvz7dll9	418	15	of	of	IN
cord-023443-pvz7dll9	418	16	the	the	DT
cord-023443-pvz7dll9	418	17	patients	patient	NNS
cord-023443-pvz7dll9	418	18	.	.	.
cord-023443-pvz7dll9	419	1	Association	Association	NNP
cord-023443-pvz7dll9	419	2	of	of	IN
cord-023443-pvz7dll9	419	3	single	single	JJ
cord-023443-pvz7dll9	419	4	nucleotide	nucleotide	JJ
cord-023443-pvz7dll9	419	5	polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	419	6	(	(	-LRB-
cord-023443-pvz7dll9	419	7	SNPs	SNPs	NNP
cord-023443-pvz7dll9	419	8	)	)	-RRB-
cord-023443-pvz7dll9	419	9	in	in	IN
cord-023443-pvz7dll9	419	10	exon	exon	NN
cord-023443-pvz7dll9	419	11	1	1	CD
cord-023443-pvz7dll9	419	12	and	and	CC
cord-023443-pvz7dll9	419	13	intron	intron	NN
cord-023443-pvz7dll9	419	14	1	1	CD
cord-023443-pvz7dll9	419	15	of	of	IN
cord-023443-pvz7dll9	419	16	the	the	DT
cord-023443-pvz7dll9	419	17	MBL	MBL	NNP
cord-023443-pvz7dll9	419	18	with	with	IN
cord-023443-pvz7dll9	419	19	the	the	DT
cord-023443-pvz7dll9	419	20	disease	disease	NN
cord-023443-pvz7dll9	419	21	,	,	,
cord-023443-pvz7dll9	419	22	clinical	clinical	JJ
cord-023443-pvz7dll9	419	23	markers	marker	NNS
cord-023443-pvz7dll9	419	24	,	,	,
cord-023443-pvz7dll9	419	25	MBL	MBL	NNP
cord-023443-pvz7dll9	419	26	levels	level	NNS
cord-023443-pvz7dll9	419	27	and	and	CC
cord-023443-pvz7dll9	419	28	MBL	mbl	NN
cord-023443-pvz7dll9	419	29	-	-	HYPH
cord-023443-pvz7dll9	419	30	induced	induce	VBN
cord-023443-pvz7dll9	419	31	complement	complement	NN
cord-023443-pvz7dll9	419	32	activity	activity	NN
cord-023443-pvz7dll9	419	33	was	be	VBD
cord-023443-pvz7dll9	419	34	analysed	analyse	VBN
cord-023443-pvz7dll9	419	35	using	use	VBG
cord-023443-pvz7dll9	419	36	standard	standard	JJ
cord-023443-pvz7dll9	419	37	statistical	statistical	JJ
cord-023443-pvz7dll9	419	38	tools	tool	NNS
cord-023443-pvz7dll9	419	39	.	.	.
cord-023443-pvz7dll9	420	1	Significantly	significantly	RB
cord-023443-pvz7dll9	420	2	higher	high	JJR
cord-023443-pvz7dll9	420	3	MBL	MBL	NNP
cord-023443-pvz7dll9	420	4	levels	level	NNS
cord-023443-pvz7dll9	420	5	and	and	CC
cord-023443-pvz7dll9	420	6	activity	activity	NN
cord-023443-pvz7dll9	420	7	were	be	VBD
cord-023443-pvz7dll9	420	8	observed	observe	VBN
cord-023443-pvz7dll9	420	9	in	in	IN
cord-023443-pvz7dll9	420	10	patients	patient	NNS
cord-023443-pvz7dll9	420	11	of	of	IN
cord-023443-pvz7dll9	420	12	bronchial	bronchial	JJ
cord-023443-pvz7dll9	420	13	asthma	asthma	NN
cord-023443-pvz7dll9	420	14	with	with	IN
cord-023443-pvz7dll9	420	15	allergic	allergic	JJ
cord-023443-pvz7dll9	420	16	rhinitis	rhinitis	NN
cord-023443-pvz7dll9	420	17	as	as	IN
cord-023443-pvz7dll9	420	18	compared	compare	VBN
cord-023443-pvz7dll9	420	19	to	to	IN
cord-023443-pvz7dll9	420	20	the	the	DT
cord-023443-pvz7dll9	420	21	controls	control	NNS
cord-023443-pvz7dll9	420	22	.	.	.
cord-023443-pvz7dll9	421	1	We	-PRON-	PRP
cord-023443-pvz7dll9	421	2	identified	identify	VBD
cord-023443-pvz7dll9	421	3	five	five	CD
cord-023443-pvz7dll9	421	4	SNPs	snp	NNS
cord-023443-pvz7dll9	421	5	,	,	,
cord-023443-pvz7dll9	421	6	of	of	IN
cord-023443-pvz7dll9	421	7	which	which	WDT
cord-023443-pvz7dll9	421	8	two	two	CD
cord-023443-pvz7dll9	421	9	,	,	,
cord-023443-pvz7dll9	421	10	A816	a816	NN
cord-023443-pvz7dll9	421	11	G	g	NN
cord-023443-pvz7dll9	421	12	in	in	IN
cord-023443-pvz7dll9	421	13	exon	exon	NN
cord-023443-pvz7dll9	421	14	1	1	CD
cord-023443-pvz7dll9	421	15	and	and	CC
cord-023443-pvz7dll9	421	16	G1011A	G1011A	NNP
cord-023443-pvz7dll9	421	17	in	in	IN
cord-023443-pvz7dll9	421	18	intron	intron	NN
cord-023443-pvz7dll9	421	19	1	1	CD
cord-023443-pvz7dll9	421	20	of	of	IN
cord-023443-pvz7dll9	421	21	the	the	DT
cord-023443-pvz7dll9	421	22	MBL	MBL	NNP
cord-023443-pvz7dll9	421	23	,	,	,
cord-023443-pvz7dll9	421	24	were	be	VBD
cord-023443-pvz7dll9	421	25	novel	novel	JJ
cord-023443-pvz7dll9	421	26	.	.	.
cord-023443-pvz7dll9	422	1	SNP	SNP	NNP
cord-023443-pvz7dll9	422	2	G1011A	G1011A	NNP
cord-023443-pvz7dll9	422	3	was	be	VBD
cord-023443-pvz7dll9	422	4	significantly	significantly	RB
cord-023443-pvz7dll9	422	5	associated	associate	VBN
cord-023443-pvz7dll9	422	6	with	with	IN
cord-023443-pvz7dll9	422	7	the	the	DT
cord-023443-pvz7dll9	422	8	disease	disease	NN
cord-023443-pvz7dll9	422	9	(	(	-LRB-
cord-023443-pvz7dll9	422	10	P	p	NN
cord-023443-pvz7dll9	422	11	¼	¼	NNP
cord-023443-pvz7dll9	422	12	0.0024	0.0024	CD
cord-023443-pvz7dll9	422	13	,	,	,
cord-023443-pvz7dll9	422	14	OR	or	CC
cord-023443-pvz7dll9	422	15	¼	¼	CD
cord-023443-pvz7dll9	422	16	5.8696	5.8696	CD
cord-023443-pvz7dll9	422	17	,	,	,
cord-023443-pvz7dll9	422	18	95	95	CD
cord-023443-pvz7dll9	422	19	%	%	NN
cord-023443-pvz7dll9	422	20	CI	ci	NN
cord-023443-pvz7dll9	422	21	:	:	:
cord-023443-pvz7dll9	422	22	1.7316	1.7316	CD
cord-023443-pvz7dll9	422	23	<	<	XX
cord-023443-pvz7dll9	422	24	OR	or	CC
cord-023443-pvz7dll9	422	25	<	<	XX
cord-023443-pvz7dll9	422	26	19.8963	19.8963	CD
cord-023443-pvz7dll9	422	27	)	)	-RRB-
cord-023443-pvz7dll9	422	28	.	.	.
cord-023443-pvz7dll9	423	1	Individuals	individual	NNS
cord-023443-pvz7dll9	423	2	with	with	IN
cord-023443-pvz7dll9	423	3	'	'	``
cord-023443-pvz7dll9	423	4	A	a	DT
cord-023443-pvz7dll9	423	5	'	'	''
cord-023443-pvz7dll9	423	6	allele	allele	NN
cord-023443-pvz7dll9	423	7	at	at	IN
cord-023443-pvz7dll9	423	8	position	position	NN
cord-023443-pvz7dll9	423	9	1011	1011	CD
cord-023443-pvz7dll9	423	10	showed	show	VBD
cord-023443-pvz7dll9	423	11	increased	increase	VBN
cord-023443-pvz7dll9	423	12	MBL	MBL	NNP
cord-023443-pvz7dll9	423	13	levels	level	NNS
cord-023443-pvz7dll9	423	14	,	,	,
cord-023443-pvz7dll9	423	15	activity	activity	NN
cord-023443-pvz7dll9	423	16	and	and	CC
cord-023443-pvz7dll9	423	17	disease	disease	NN
cord-023443-pvz7dll9	423	18	severity	severity	NN
cord-023443-pvz7dll9	423	19	.	.	.
cord-023443-pvz7dll9	424	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	424	2	results	result	NNS
cord-023443-pvz7dll9	424	3	suggest	suggest	VBP
cord-023443-pvz7dll9	424	4	that	that	IN
cord-023443-pvz7dll9	424	5	'	'	``
cord-023443-pvz7dll9	424	6	A	a	DT
cord-023443-pvz7dll9	424	7	'	'	''
cord-023443-pvz7dll9	424	8	allele	allele	NN
cord-023443-pvz7dll9	424	9	at	at	IN
cord-023443-pvz7dll9	424	10	position	position	NN
cord-023443-pvz7dll9	424	11	1011	1011	CD
cord-023443-pvz7dll9	424	12	leading	lead	VBG
cord-023443-pvz7dll9	424	13	to	to	IN
cord-023443-pvz7dll9	424	14	high	high	JJ
cord-023443-pvz7dll9	424	15	MBL	MBL	NNP
cord-023443-pvz7dll9	424	16	levels	level	NNS
cord-023443-pvz7dll9	424	17	and	and	CC
cord-023443-pvz7dll9	424	18	complement	complement	NN
cord-023443-pvz7dll9	424	19	activity	activity	NN
cord-023443-pvz7dll9	424	20	may	may	MD
cord-023443-pvz7dll9	424	21	be	be	VB
cord-023443-pvz7dll9	424	22	contributing	contribute	VBG
cord-023443-pvz7dll9	424	23	to	to	IN
cord-023443-pvz7dll9	424	24	the	the	DT
cord-023443-pvz7dll9	424	25	severity	severity	NN
cord-023443-pvz7dll9	424	26	of	of	IN
cord-023443-pvz7dll9	424	27	bronchial	bronchial	JJ
cord-023443-pvz7dll9	424	28	asthma	asthma	NN
cord-023443-pvz7dll9	424	29	and	and	CC
cord-023443-pvz7dll9	424	30	allergic	allergic	JJ
cord-023443-pvz7dll9	424	31	airway	airway	NN
cord-023443-pvz7dll9	424	32	inflammation	inflammation	NN
cord-023443-pvz7dll9	424	33	.	.	.
cord-023443-pvz7dll9	425	1	Serum	serum	NN
cord-023443-pvz7dll9	425	2	resistance	resistance	NN
cord-023443-pvz7dll9	425	3	of	of	IN
cord-023443-pvz7dll9	425	4	Borrelia	Borrelia	NNP
cord-023443-pvz7dll9	425	5	burgdorferi	burgdorferi	NN
cord-023443-pvz7dll9	425	6	strains	strain	NNS
cord-023443-pvz7dll9	425	7	belonging	belong	VBG
cord-023443-pvz7dll9	425	8	to	to	IN
cord-023443-pvz7dll9	425	9	the	the	DT
cord-023443-pvz7dll9	425	10	B.	B.	NNP
cord-023443-pvz7dll9	425	11	afzelii	afzelii	NNP
cord-023443-pvz7dll9	425	12	and	and	CC
cord-023443-pvz7dll9	425	13	B.	B.	NNP
cord-023443-pvz7dll9	425	14	burgdorferi	burgdorferi	NNP
cord-023443-pvz7dll9	425	15	sensu	sensu	NNP
cord-023443-pvz7dll9	425	16	stricto	stricto	NNP
cord-023443-pvz7dll9	425	17	genospecies	genospecies	NNP
cord-023443-pvz7dll9	425	18	is	be	VBZ
cord-023443-pvz7dll9	425	19	dependent	dependent	JJ
cord-023443-pvz7dll9	425	20	on	on	IN
cord-023443-pvz7dll9	425	21	binding	bind	VBG
cord-023443-pvz7dll9	425	22	of	of	IN
cord-023443-pvz7dll9	425	23	complement	complement	JJ
cord-023443-pvz7dll9	425	24	inhibitor	inhibitor	NN
cord-023443-pvz7dll9	425	25	factor	factor	NN
cord-023443-pvz7dll9	425	26	H.	h.	NN
cord-023443-pvz7dll9	426	1	We	-PRON-	PRP
cord-023443-pvz7dll9	426	2	recently	recently	RB
cord-023443-pvz7dll9	426	3	reported	report	VBD
cord-023443-pvz7dll9	426	4	that	that	IN
cord-023443-pvz7dll9	426	5	factor	factor	NN
cord-023443-pvz7dll9	426	6	H	h	NN
cord-023443-pvz7dll9	426	7	binding	binding	NN
cord-023443-pvz7dll9	426	8	by	by	IN
cord-023443-pvz7dll9	426	9	B.	B.	NNP
cord-023443-pvz7dll9	426	10	burgdorferi	burgdorferi	NNP
cord-023443-pvz7dll9	426	11	is	be	VBZ
cord-023443-pvz7dll9	426	12	due	due	JJ
cord-023443-pvz7dll9	426	13	to	to	IN
cord-023443-pvz7dll9	426	14	inducible	inducible	JJ
cord-023443-pvz7dll9	426	15	expression	expression	NN
cord-023443-pvz7dll9	426	16	of	of	IN
cord-023443-pvz7dll9	426	17	several	several	JJ
cord-023443-pvz7dll9	426	18	approximately	approximately	RB
cord-023443-pvz7dll9	426	19	20	20	CD
cord-023443-pvz7dll9	426	20	kDa	kDa	NNS
cord-023443-pvz7dll9	426	21	plasmid	plasmid	NN
cord-023443-pvz7dll9	426	22	-	-	HYPH
cord-023443-pvz7dll9	426	23	encoded	encode	VBN
cord-023443-pvz7dll9	426	24	,	,	,
cord-023443-pvz7dll9	426	25	surface	surface	NN
cord-023443-pvz7dll9	426	26	-	-	HYPH
cord-023443-pvz7dll9	426	27	exposed	expose	VBN
cord-023443-pvz7dll9	426	28	lipoproteins	lipoprotein	NNS
cord-023443-pvz7dll9	426	29	related	relate	VBN
cord-023443-pvz7dll9	426	30	to	to	IN
cord-023443-pvz7dll9	426	31	OspE	OspE	NNP
cord-023443-pvz7dll9	426	32	(	(	-LRB-
cord-023443-pvz7dll9	426	33	e.g.	e.g.	RB
cord-023443-pvz7dll9	426	34	ErpA	ErpA	NNP
cord-023443-pvz7dll9	426	35	,	,	,
cord-023443-pvz7dll9	426	36	ErpP	ErpP	NNP
cord-023443-pvz7dll9	426	37	and	and	CC
cord-023443-pvz7dll9	426	38	P21	P21	NNP
cord-023443-pvz7dll9	426	39	)	)	-RRB-
cord-023443-pvz7dll9	426	40	.	.	.
cord-023443-pvz7dll9	427	1	In	in	IN
cord-023443-pvz7dll9	427	2	addition	addition	NN
cord-023443-pvz7dll9	427	3	,	,	,
cord-023443-pvz7dll9	427	4	a	a	DT
cord-023443-pvz7dll9	427	5	second	second	JJ
cord-023443-pvz7dll9	427	6	class	class	NN
cord-023443-pvz7dll9	427	7	of	of	IN
cord-023443-pvz7dll9	427	8	factor	factor	NN
cord-023443-pvz7dll9	427	9	H	h	NN
cord-023443-pvz7dll9	427	10	-	-	HYPH
cord-023443-pvz7dll9	427	11	binding	bind	VBG
cord-023443-pvz7dll9	427	12	proteins	protein	NNS
cord-023443-pvz7dll9	427	13	of	of	IN
cord-023443-pvz7dll9	427	14	approximately	approximately	RB
cord-023443-pvz7dll9	427	15	27	27	CD
cord-023443-pvz7dll9	427	16	-	-	SYM
cord-023443-pvz7dll9	427	17	35	35	CD
cord-023443-pvz7dll9	427	18	kDa	kDa	NNP
cord-023443-pvz7dll9	427	19	has	have	VBZ
cord-023443-pvz7dll9	427	20	been	be	VBN
cord-023443-pvz7dll9	427	21	described	describe	VBN
cord-023443-pvz7dll9	427	22	.	.	.
cord-023443-pvz7dll9	428	1	The	the	DT
cord-023443-pvz7dll9	428	2	OspE	OspE	NNP
cord-023443-pvz7dll9	428	3	-	-	HYPH
cord-023443-pvz7dll9	428	4	related	relate	VBN
cord-023443-pvz7dll9	428	5	lipoproteins	lipoprotein	NNS
cord-023443-pvz7dll9	428	6	are	be	VBP
cord-023443-pvz7dll9	428	7	dramatically	dramatically	RB
cord-023443-pvz7dll9	428	8	induced	induce	VBN
cord-023443-pvz7dll9	428	9	by	by	IN
cord-023443-pvz7dll9	428	10	B.	B.	NNP
cord-023443-pvz7dll9	428	11	burgdorferi	burgdorferi	NN
cord-023443-pvz7dll9	428	12	during	during	IN
cord-023443-pvz7dll9	428	13	transmission	transmission	NN
cord-023443-pvz7dll9	428	14	from	from	IN
cord-023443-pvz7dll9	428	15	its	-PRON-	PRP$
cord-023443-pvz7dll9	428	16	tick	tick	NN
cord-023443-pvz7dll9	428	17	vector	vector	NN
cord-023443-pvz7dll9	428	18	into	into	IN
cord-023443-pvz7dll9	428	19	the	the	DT
cord-023443-pvz7dll9	428	20	mammalian	mammalian	JJ
cord-023443-pvz7dll9	428	21	host	host	NN
cord-023443-pvz7dll9	428	22	.	.	.
cord-023443-pvz7dll9	429	1	The	the	DT
cord-023443-pvz7dll9	429	2	induction	induction	NN
cord-023443-pvz7dll9	429	3	of	of	IN
cord-023443-pvz7dll9	429	4	OspE	OspE	NNP
cord-023443-pvz7dll9	429	5	-	-	HYPH
cord-023443-pvz7dll9	429	6	related	relate	VBN
cord-023443-pvz7dll9	429	7	lipoproteins	lipoprotein	NNS
cord-023443-pvz7dll9	429	8	during	during	IN
cord-023443-pvz7dll9	429	9	mammalian	mammalian	JJ
cord-023443-pvz7dll9	429	10	infection	infection	NN
cord-023443-pvz7dll9	429	11	may	may	MD
cord-023443-pvz7dll9	429	12	play	play	VB
cord-023443-pvz7dll9	429	13	a	a	DT
cord-023443-pvz7dll9	429	14	key	key	JJ
cord-023443-pvz7dll9	429	15	a	a	DT
cord-023443-pvz7dll9	429	16	role	role	NN
cord-023443-pvz7dll9	429	17	in	in	IN
cord-023443-pvz7dll9	429	18	the	the	DT
cord-023443-pvz7dll9	429	19	borrelial	borrelial	JJ
cord-023443-pvz7dll9	429	20	evasion	evasion	NN
cord-023443-pvz7dll9	429	21	of	of	IN
cord-023443-pvz7dll9	429	22	the	the	DT
cord-023443-pvz7dll9	429	23	host	host	NN
cord-023443-pvz7dll9	429	24	's	's	POS
cord-023443-pvz7dll9	429	25	immune	immune	JJ
cord-023443-pvz7dll9	429	26	system	system	NN
cord-023443-pvz7dll9	429	27	.	.	.
cord-023443-pvz7dll9	430	1	The	the	DT
cord-023443-pvz7dll9	430	2	goal	goal	NN
cord-023443-pvz7dll9	430	3	of	of	IN
cord-023443-pvz7dll9	430	4	the	the	DT
cord-023443-pvz7dll9	430	5	present	present	JJ
cord-023443-pvz7dll9	430	6	study	study	NN
cord-023443-pvz7dll9	430	7	was	be	VBD
cord-023443-pvz7dll9	430	8	to	to	TO
cord-023443-pvz7dll9	430	9	define	define	VB
cord-023443-pvz7dll9	430	10	the	the	DT
cord-023443-pvz7dll9	430	11	factor	factor	NN
cord-023443-pvz7dll9	430	12	H	h	NN
cord-023443-pvz7dll9	430	13	-	-	HYPH
cord-023443-pvz7dll9	430	14	binding	bind	VBG
cord-023443-pvz7dll9	430	15	regions	region	NNS
cord-023443-pvz7dll9	430	16	of	of	IN
cord-023443-pvz7dll9	430	17	OspE	ospe	NN
cord-023443-pvz7dll9	430	18	-	-	HYPH
cord-023443-pvz7dll9	430	19	related	relate	VBN
cord-023443-pvz7dll9	430	20	proteins	protein	NNS
cord-023443-pvz7dll9	430	21	using	use	VBG
cord-023443-pvz7dll9	430	22	mutagenesis	mutagenesis	NN
cord-023443-pvz7dll9	430	23	,	,	,
cord-023443-pvz7dll9	430	24	peptide	peptide	NN
cord-023443-pvz7dll9	430	25	mapping	mapping	NN
cord-023443-pvz7dll9	430	26	and	and	CC
cord-023443-pvz7dll9	430	27	surface	surface	NN
cord-023443-pvz7dll9	430	28	plasmon	plasmon	NNP
cord-023443-pvz7dll9	430	29	resonance	resonance	NN
cord-023443-pvz7dll9	430	30	analysis	analysis	NN
cord-023443-pvz7dll9	430	31	(	(	-LRB-
cord-023443-pvz7dll9	430	32	Biacore	Biacore	NNP
cord-023443-pvz7dll9	430	33	)	)	-RRB-
cord-023443-pvz7dll9	430	34	.	.	.
cord-023443-pvz7dll9	431	1	The	the	DT
cord-023443-pvz7dll9	431	2	combined	combine	VBN
cord-023443-pvz7dll9	431	3	studies	study	NNS
cord-023443-pvz7dll9	431	4	revealed	reveal	VBD
cord-023443-pvz7dll9	431	5	that	that	IN
cord-023443-pvz7dll9	431	6	the	the	DT
cord-023443-pvz7dll9	431	7	C	c	NN
cord-023443-pvz7dll9	431	8	-	-	HYPH
cord-023443-pvz7dll9	431	9	terminal	terminal	NN
cord-023443-pvz7dll9	431	10	regions	region	NNS
cord-023443-pvz7dll9	431	11	of	of	IN
cord-023443-pvz7dll9	431	12	both	both	CC
cord-023443-pvz7dll9	431	13	human	human	JJ
cord-023443-pvz7dll9	431	14	and	and	CC
cord-023443-pvz7dll9	431	15	mouse	mouse	NN
cord-023443-pvz7dll9	431	16	factor	factor	NN
cord-023443-pvz7dll9	431	17	H	H	NNP
cord-023443-pvz7dll9	431	18	(	(	-LRB-
cord-023443-pvz7dll9	431	19	SCRs	SCRs	NNP
cord-023443-pvz7dll9	431	20	18	18	CD
cord-023443-pvz7dll9	431	21	-	-	SYM
cord-023443-pvz7dll9	431	22	20	20	CD
cord-023443-pvz7dll9	431	23	)	)	-RRB-
cord-023443-pvz7dll9	431	24	specifically	specifically	RB
cord-023443-pvz7dll9	431	25	bind	bind	VB
cord-023443-pvz7dll9	431	26	to	to	IN
cord-023443-pvz7dll9	431	27	OspE	OspE	NNP
cord-023443-pvz7dll9	431	28	-	-	HYPH
cord-023443-pvz7dll9	431	29	related	relate	VBN
cord-023443-pvz7dll9	431	30	lipoproteins	lipoprotein	NNS
cord-023443-pvz7dll9	431	31	.	.	.
cord-023443-pvz7dll9	432	1	We	-PRON-	PRP
cord-023443-pvz7dll9	432	2	also	also	RB
cord-023443-pvz7dll9	432	3	found	find	VBD
cord-023443-pvz7dll9	432	4	FHR-1	FHR-1	NNP
cord-023443-pvz7dll9	432	5	,	,	,
cord-023443-pvz7dll9	433	1	whose	whose	WP$
cord-023443-pvz7dll9	433	2	C	C	NNP
cord-023443-pvz7dll9	433	3	-	-	HYPH
cord-023443-pvz7dll9	433	4	terminal	terminal	NN
cord-023443-pvz7dll9	433	5	SCRs	scr	NNS
cord-023443-pvz7dll9	433	6	3	3	CD
cord-023443-pvz7dll9	433	7	-	-	SYM
cord-023443-pvz7dll9	433	8	5	5	CD
cord-023443-pvz7dll9	433	9	are	be	VBP
cord-023443-pvz7dll9	433	10	homologous	homologous	JJ
cord-023443-pvz7dll9	433	11	to	to	IN
cord-023443-pvz7dll9	433	12	SCRs	scr	NNS
cord-023443-pvz7dll9	433	13	18	18	CD
cord-023443-pvz7dll9	433	14	-	-	SYM
cord-023443-pvz7dll9	433	15	20	20	CD
cord-023443-pvz7dll9	433	16	of	of	IN
cord-023443-pvz7dll9	433	17	factor	factor	NN
cord-023443-pvz7dll9	433	18	H	h	NN
cord-023443-pvz7dll9	433	19	,	,	,
cord-023443-pvz7dll9	433	20	to	to	TO
cord-023443-pvz7dll9	433	21	bind	bind	VB
cord-023443-pvz7dll9	433	22	to	to	IN
cord-023443-pvz7dll9	433	23	OspE.	OspE.	NNP
cord-023443-pvz7dll9	434	1	Peptide	peptide	NN
cord-023443-pvz7dll9	434	2	mapping	mapping	NN
cord-023443-pvz7dll9	434	3	revealed	reveal	VBD
cord-023443-pvz7dll9	434	4	five	five	CD
cord-023443-pvz7dll9	434	5	putative	putative	JJ
cord-023443-pvz7dll9	434	6	regions	region	NNS
cord-023443-pvz7dll9	434	7	(	(	-LRB-
cord-023443-pvz7dll9	434	8	designated	designate	VBN
cord-023443-pvz7dll9	434	9	I	I	NNP
cord-023443-pvz7dll9	434	10	-	-	HYPH
cord-023443-pvz7dll9	434	11	V	V	NNP
cord-023443-pvz7dll9	434	12	)	)	-RRB-
cord-023443-pvz7dll9	434	13	in	in	IN
cord-023443-pvz7dll9	434	14	OspE	OspE	NNP
cord-023443-pvz7dll9	434	15	that	that	WDT
cord-023443-pvz7dll9	434	16	could	could	MD
cord-023443-pvz7dll9	434	17	directly	directly	RB
cord-023443-pvz7dll9	434	18	interact	interact	VB
cord-023443-pvz7dll9	434	19	with	with	IN
cord-023443-pvz7dll9	434	20	factor	factor	NN
cord-023443-pvz7dll9	434	21	H.	h.	NN
cord-023443-pvz7dll9	434	22	Deleting	delete	VBG
cord-023443-pvz7dll9	434	23	the	the	DT
cord-023443-pvz7dll9	434	24	C	C	NNP
cord-023443-pvz7dll9	434	25	-	-	HYPH
cord-023443-pvz7dll9	434	26	terminal	terminal	NN
cord-023443-pvz7dll9	434	27	15	15	CD
cord-023443-pvz7dll9	434	28	amino	amino	NN
cord-023443-pvz7dll9	434	29	acid	acid	NN
cord-023443-pvz7dll9	434	30	residues	residue	NNS
cord-023443-pvz7dll9	434	31	from	from	IN
cord-023443-pvz7dll9	434	32	region	region	NN
cord-023443-pvz7dll9	434	33	V	v	NN
cord-023443-pvz7dll9	434	34	of	of	IN
cord-023443-pvz7dll9	434	35	P21	P21	NNP
cord-023443-pvz7dll9	434	36	abolished	abolish	VBD
cord-023443-pvz7dll9	434	37	its	-PRON-	PRP$
cord-023443-pvz7dll9	434	38	ability	ability	NN
cord-023443-pvz7dll9	434	39	to	to	TO
cord-023443-pvz7dll9	434	40	bind	bind	VB
cord-023443-pvz7dll9	434	41	factor	factor	NN
cord-023443-pvz7dll9	434	42	H.	h.	NN
cord-023443-pvz7dll9	435	1	At	at	IN
cord-023443-pvz7dll9	435	2	the	the	DT
cord-023443-pvz7dll9	435	3	same	same	JJ
cord-023443-pvz7dll9	435	4	time	time	NN
cord-023443-pvz7dll9	435	5	,	,	,
cord-023443-pvz7dll9	435	6	however	however	RB
cord-023443-pvz7dll9	435	7	,	,	,
cord-023443-pvz7dll9	435	8	synthetic	synthetic	JJ
cord-023443-pvz7dll9	435	9	peptides	peptide	NNS
cord-023443-pvz7dll9	435	10	corresponding	correspond	VBG
cord-023443-pvz7dll9	435	11	to	to	IN
cord-023443-pvz7dll9	435	12	the	the	DT
cord-023443-pvz7dll9	435	13	C	C	NNP
cord-023443-pvz7dll9	435	14	-	-	HYPH
cord-023443-pvz7dll9	435	15	termini	termini	NNP
cord-023443-pvz7dll9	435	16	of	of	IN
cord-023443-pvz7dll9	435	17	OspE	OspE	NNP
cord-023443-pvz7dll9	435	18	,	,	,
cord-023443-pvz7dll9	435	19	P21	P21	NNP
cord-023443-pvz7dll9	435	20	and	and	CC
cord-023443-pvz7dll9	435	21	ErpP	ErpP	NNP
cord-023443-pvz7dll9	435	22	did	do	VBD
cord-023443-pvz7dll9	435	23	not	not	RB
cord-023443-pvz7dll9	435	24	inhibit	inhibit	VB
cord-023443-pvz7dll9	435	25	factor	factor	NN
cord-023443-pvz7dll9	435	26	H	h	NN
cord-023443-pvz7dll9	435	27	binding	bind	VBG
cord-023443-pvz7dll9	435	28	to	to	IN
cord-023443-pvz7dll9	435	29	OspE.	ospe.	XX
cord-023443-pvz7dll9	436	1	Thus	thus	RB
cord-023443-pvz7dll9	436	2	,	,	,
cord-023443-pvz7dll9	436	3	the	the	DT
cord-023443-pvz7dll9	436	4	C	c	NN
cord-023443-pvz7dll9	436	5	-	-	HYPH
cord-023443-pvz7dll9	436	6	terminal	terminal	NN
cord-023443-pvz7dll9	436	7	-	-	HYPH
cord-023443-pvz7dll9	436	8	binding	bind	VBG
cord-023443-pvz7dll9	436	9	region	region	NN
cord-023443-pvz7dll9	436	10	V	v	NN
cord-023443-pvz7dll9	436	11	appears	appear	VBZ
cord-023443-pvz7dll9	436	12	to	to	TO
cord-023443-pvz7dll9	436	13	be	be	VB
cord-023443-pvz7dll9	436	14	necessary	necessary	JJ
cord-023443-pvz7dll9	436	15	but	but	CC
cord-023443-pvz7dll9	436	16	not	not	RB
cord-023443-pvz7dll9	436	17	sufficient	sufficient	JJ
cord-023443-pvz7dll9	436	18	for	for	IN
cord-023443-pvz7dll9	436	19	factor	factor	NN
cord-023443-pvz7dll9	436	20	H	h	NN
cord-023443-pvz7dll9	436	21	binding	binding	NN
cord-023443-pvz7dll9	436	22	.	.	.
cord-023443-pvz7dll9	437	1	When	when	WRB
cord-023443-pvz7dll9	437	2	a	a	DT
cord-023443-pvz7dll9	437	3	more	more	RBR
cord-023443-pvz7dll9	437	4	specific	specific	JJ
cord-023443-pvz7dll9	437	5	mutation	mutation	NN
cord-023443-pvz7dll9	437	6	strategy	strategy	NN
cord-023443-pvz7dll9	437	7	was	be	VBD
cord-023443-pvz7dll9	437	8	employed	employ	VBN
cord-023443-pvz7dll9	437	9	,	,	,
cord-023443-pvz7dll9	437	10	where	where	WRB
cord-023443-pvz7dll9	437	11	single	single	JJ
cord-023443-pvz7dll9	437	12	amino	amino	NN
cord-023443-pvz7dll9	437	13	acid	acid	NN
cord-023443-pvz7dll9	437	14	residues	residue	NNS
cord-023443-pvz7dll9	437	15	in	in	IN
cord-023443-pvz7dll9	437	16	peptides	peptide	NNS
cord-023443-pvz7dll9	437	17	spanning	span	VBG
cord-023443-pvz7dll9	437	18	over	over	IN
cord-023443-pvz7dll9	437	19	the	the	DT
cord-023443-pvz7dll9	437	20	factor	factor	NN
cord-023443-pvz7dll9	437	21	H	h	NN
cord-023443-pvz7dll9	437	22	-	-	HYPH
cord-023443-pvz7dll9	437	23	binding	bind	VBG
cord-023443-pvz7dll9	437	24	regions	region	NNS
cord-023443-pvz7dll9	437	25	were	be	VBD
cord-023443-pvz7dll9	437	26	mutated	mutate	VBN
cord-023443-pvz7dll9	437	27	to	to	IN
cord-023443-pvz7dll9	437	28	alanines	alanine	NNS
cord-023443-pvz7dll9	437	29	,	,	,
cord-023443-pvz7dll9	437	30	we	-PRON-	PRP
cord-023443-pvz7dll9	437	31	observed	observe	VBD
cord-023443-pvz7dll9	437	32	that	that	IN
cord-023443-pvz7dll9	437	33	lysines	lysine	NNS
cord-023443-pvz7dll9	437	34	in	in	IN
cord-023443-pvz7dll9	437	35	the	the	DT
cord-023443-pvz7dll9	437	36	factor	factor	NN
cord-023443-pvz7dll9	437	37	H	h	NN
cord-023443-pvz7dll9	437	38	-	-	HYPH
cord-023443-pvz7dll9	437	39	binding	bind	VBG
cord-023443-pvz7dll9	437	40	regions	region	NNS
cord-023443-pvz7dll9	437	41	of	of	IN
cord-023443-pvz7dll9	437	42	OspE	OspE	NNP
cord-023443-pvz7dll9	437	43	were	be	VBD
cord-023443-pvz7dll9	437	44	required	require	VBN
cord-023443-pvz7dll9	437	45	for	for	IN
cord-023443-pvz7dll9	437	46	factor	factor	NN
cord-023443-pvz7dll9	437	47	H	h	NN
cord-023443-pvz7dll9	437	48	binding	binding	NN
cord-023443-pvz7dll9	437	49	.	.	.
cord-023443-pvz7dll9	438	1	The	the	DT
cord-023443-pvz7dll9	438	2	combined	combined	JJ
cord-023443-pvz7dll9	438	3	data	datum	NNS
cord-023443-pvz7dll9	438	4	have	have	VBP
cord-023443-pvz7dll9	438	5	revealed	reveal	VBN
cord-023443-pvz7dll9	438	6	that	that	IN
cord-023443-pvz7dll9	438	7	key	key	JJ
cord-023443-pvz7dll9	438	8	lysine	lysine	NN
cord-023443-pvz7dll9	438	9	residues	residue	NNS
cord-023443-pvz7dll9	438	10	in	in	IN
cord-023443-pvz7dll9	438	11	OspE	OspE	NNP
cord-023443-pvz7dll9	438	12	-	-	HYPH
cord-023443-pvz7dll9	438	13	related	relate	VBN
cord-023443-pvz7dll9	438	14	lipoproteins	lipoprotein	NNS
cord-023443-pvz7dll9	438	15	and	and	CC
cord-023443-pvz7dll9	438	16	ionic	ionic	JJ
cord-023443-pvz7dll9	438	17	interactions	interaction	NNS
cord-023443-pvz7dll9	438	18	are	be	VBP
cord-023443-pvz7dll9	438	19	crucial	crucial	JJ
cord-023443-pvz7dll9	438	20	for	for	IN
cord-023443-pvz7dll9	438	21	factor	factor	NN
cord-023443-pvz7dll9	438	22	H	h	NN
cord-023443-pvz7dll9	438	23	interactions	interaction	NNS
cord-023443-pvz7dll9	438	24	.	.	.
cord-023443-pvz7dll9	439	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	439	2	,	,	,
cord-023443-pvz7dll9	439	3	binding	bind	VBG
cord-023443-pvz7dll9	439	4	of	of	IN
cord-023443-pvz7dll9	439	5	OspE	OspE	NNP
cord-023443-pvz7dll9	439	6	to	to	IN
cord-023443-pvz7dll9	439	7	the	the	DT
cord-023443-pvz7dll9	439	8	C	C	NNP
cord-023443-pvz7dll9	439	9	-	-	HYPH
cord-023443-pvz7dll9	439	10	termini	termini	NNP
cord-023443-pvz7dll9	439	11	of	of	IN
cord-023443-pvz7dll9	439	12	both	both	DT
cord-023443-pvz7dll9	439	13	mouse	mouse	NN
cord-023443-pvz7dll9	439	14	and	and	CC
cord-023443-pvz7dll9	439	15	human	human	NN
cord-023443-pvz7dll9	439	16	factor	factor	NN
cord-023443-pvz7dll9	440	1	H	H	NNP
cord-023443-pvz7dll9	440	2	suggests	suggest	VBZ
cord-023443-pvz7dll9	440	3	that	that	IN
cord-023443-pvz7dll9	440	4	Borrelia	Borrelia	NNP
cord-023443-pvz7dll9	440	5	spirochetes	spirochete	NNS
cord-023443-pvz7dll9	440	6	utilize	utilize	VBP
cord-023443-pvz7dll9	440	7	analogous	analogous	JJ
cord-023443-pvz7dll9	440	8	complement	complement	NN
cord-023443-pvz7dll9	440	9	resistance	resistance	NN
cord-023443-pvz7dll9	440	10	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	440	11	in	in	IN
cord-023443-pvz7dll9	440	12	both	both	DT
cord-023443-pvz7dll9	440	13	rodents	rodent	NNS
cord-023443-pvz7dll9	440	14	and	and	CC
cord-023443-pvz7dll9	440	15	man	man	NN
cord-023443-pvz7dll9	440	16	.	.	.
cord-023443-pvz7dll9	441	1	In	in	IN
cord-023443-pvz7dll9	441	2	Borrelia	Borrelia	NNP
cord-023443-pvz7dll9	441	3	garinii	garinii	NN
cord-023443-pvz7dll9	441	4	strains	strain	NNS
cord-023443-pvz7dll9	441	5	,	,	,
cord-023443-pvz7dll9	441	6	which	which	WDT
cord-023443-pvz7dll9	441	7	in	in	IN
cord-023443-pvz7dll9	441	8	in	in	IN
cord-023443-pvz7dll9	441	9	vitro	vitro	FW
cord-023443-pvz7dll9	441	10	analyses	analysis	NNS
cord-023443-pvz7dll9	441	11	have	have	VBP
cord-023443-pvz7dll9	441	12	been	be	VBN
cord-023443-pvz7dll9	441	13	found	find	VBN
cord-023443-pvz7dll9	441	14	to	to	TO
cord-023443-pvz7dll9	441	15	be	be	VB
cord-023443-pvz7dll9	441	16	sensitive	sensitive	JJ
cord-023443-pvz7dll9	441	17	to	to	TO
cord-023443-pvz7dll9	441	18	complement	complement	VB
cord-023443-pvz7dll9	441	19	killing	killing	NN
cord-023443-pvz7dll9	441	20	,	,	,
cord-023443-pvz7dll9	441	21	differences	difference	NNS
cord-023443-pvz7dll9	441	22	in	in	IN
cord-023443-pvz7dll9	441	23	the	the	DT
cord-023443-pvz7dll9	441	24	OspE	OspE	NNP
cord-023443-pvz7dll9	441	25	sequences	sequence	NNS
cord-023443-pvz7dll9	441	26	as	as	RB
cord-023443-pvz7dll9	441	27	well	well	RB
cord-023443-pvz7dll9	441	28	as	as	IN
cord-023443-pvz7dll9	441	29	in	in	IN
cord-023443-pvz7dll9	441	30	the	the	DT
cord-023443-pvz7dll9	441	31	expression	expression	NN
cord-023443-pvz7dll9	441	32	of	of	IN
cord-023443-pvz7dll9	441	33	factor	factor	NN
cord-023443-pvz7dll9	441	34	H	h	NN
cord-023443-pvz7dll9	441	35	-	-	HYPH
cord-023443-pvz7dll9	441	36	binding	bind	VBG
cord-023443-pvz7dll9	441	37	proteins	protein	NNS
cord-023443-pvz7dll9	441	38	may	may	MD
cord-023443-pvz7dll9	441	39	account	account	VB
cord-023443-pvz7dll9	441	40	for	for	IN
cord-023443-pvz7dll9	441	41	their	-PRON-	PRP$
cord-023443-pvz7dll9	441	42	susceptibility	susceptibility	NN
cord-023443-pvz7dll9	441	43	to	to	IN
cord-023443-pvz7dll9	441	44	serum	serum	NN
cord-023443-pvz7dll9	441	45	lysis	lysis	NN
cord-023443-pvz7dll9	441	46	.	.	.
cord-023443-pvz7dll9	442	1	Role	role	NN
cord-023443-pvz7dll9	442	2	of	of	IN
cord-023443-pvz7dll9	442	3	YadA	YadA	NNP
cord-023443-pvz7dll9	442	4	,	,	,
cord-023443-pvz7dll9	442	5	Ail	Ail	NNP
cord-023443-pvz7dll9	442	6	and	and	CC
cord-023443-pvz7dll9	442	7	Lipopolysaccharide	Lipopolysaccharide	NNP
cord-023443-pvz7dll9	442	8	in	in	IN
cord-023443-pvz7dll9	442	9	Serum	Serum	NNP
cord-023443-pvz7dll9	442	10	Resistance	Resistance	NNP
cord-023443-pvz7dll9	442	11	of	of	IN
cord-023443-pvz7dll9	442	12	Yersinia	Yersinia	NNP
cord-023443-pvz7dll9	442	13	enterocolitica	enterocolitica	NNP
cord-023443-pvz7dll9	442	14	Serotype	Serotype	NNP
cord-023443-pvz7dll9	443	1	O:3	O:3	NNP
cord-023443-pvz7dll9	443	2	Mannan	Mannan	NNP
cord-023443-pvz7dll9	443	3	-	-	HYPH
cord-023443-pvz7dll9	443	4	binding	bind	VBG
cord-023443-pvz7dll9	443	5	lectin	lectin	NN
cord-023443-pvz7dll9	443	6	(	(	-LRB-
cord-023443-pvz7dll9	443	7	MBL	MBL	NNP
cord-023443-pvz7dll9	443	8	)	)	-RRB-
cord-023443-pvz7dll9	443	9	,	,	,
cord-023443-pvz7dll9	443	10	L	l	NN
cord-023443-pvz7dll9	443	11	-	-	HYPH
cord-023443-pvz7dll9	443	12	ficolin	ficolin	NNP
cord-023443-pvz7dll9	443	13	and	and	CC
cord-023443-pvz7dll9	443	14	H	h	NN
cord-023443-pvz7dll9	443	15	-	-	HYPH
cord-023443-pvz7dll9	443	16	ficolin	ficolin	NNP
cord-023443-pvz7dll9	443	17	are	be	VBP
cord-023443-pvz7dll9	443	18	pattern	pattern	NN
cord-023443-pvz7dll9	443	19	recognition	recognition	NN
cord-023443-pvz7dll9	443	20	molecules	molecule	NNS
cord-023443-pvz7dll9	443	21	of	of	IN
cord-023443-pvz7dll9	443	22	the	the	DT
cord-023443-pvz7dll9	443	23	innate	innate	JJ
cord-023443-pvz7dll9	443	24	immune	immune	JJ
cord-023443-pvz7dll9	443	25	system	system	NN
cord-023443-pvz7dll9	443	26	.	.	.
cord-023443-pvz7dll9	444	1	We	-PRON-	PRP
cord-023443-pvz7dll9	444	2	investigated	investigate	VBD
cord-023443-pvz7dll9	444	3	the	the	DT
cord-023443-pvz7dll9	444	4	ability	ability	NN
cord-023443-pvz7dll9	444	5	of	of	IN
cord-023443-pvz7dll9	444	6	these	these	DT
cord-023443-pvz7dll9	444	7	molecules	molecule	NNS
cord-023443-pvz7dll9	444	8	to	to	TO
cord-023443-pvz7dll9	444	9	bind	bind	VB
cord-023443-pvz7dll9	444	10	to	to	IN
cord-023443-pvz7dll9	444	11	different	different	JJ
cord-023443-pvz7dll9	444	12	serotypes	serotype	NNS
cord-023443-pvz7dll9	444	13	and	and	CC
cord-023443-pvz7dll9	444	14	noncapsulated	noncapsulated	JJ
cord-023443-pvz7dll9	444	15	variants	variant	NNS
cord-023443-pvz7dll9	444	16	of	of	IN
cord-023443-pvz7dll9	444	17	Streptococcus	Streptococcus	NNP
cord-023443-pvz7dll9	444	18	pneumonia	pneumonia	NN
cord-023443-pvz7dll9	444	19	and	and	CC
cord-023443-pvz7dll9	444	20	Staphylococcus	Staphylococcus	NNP
cord-023443-pvz7dll9	444	21	aureus	aureus	NN
cord-023443-pvz7dll9	444	22	.	.	.
cord-023443-pvz7dll9	445	1	We	-PRON-	PRP
cord-023443-pvz7dll9	445	2	found	find	VBD
cord-023443-pvz7dll9	445	3	that	that	IN
cord-023443-pvz7dll9	445	4	MBL	MBL	NNP
cord-023443-pvz7dll9	445	5	binds	bind	VBZ
cord-023443-pvz7dll9	445	6	to	to	IN
cord-023443-pvz7dll9	445	7	noncapsulated	noncapsulated	NNP
cord-023443-pvz7dll9	445	8	S.	S.	NNP
cord-023443-pvz7dll9	445	9	aureus	aureus	NN
cord-023443-pvz7dll9	445	10	strain	strain	NN
cord-023443-pvz7dll9	445	11	(	(	-LRB-
cord-023443-pvz7dll9	445	12	Wood	wood	NN
cord-023443-pvz7dll9	445	13	)	)	-RRB-
cord-023443-pvz7dll9	445	14	but	but	CC
cord-023443-pvz7dll9	445	15	not	not	RB
cord-023443-pvz7dll9	445	16	any	any	DT
cord-023443-pvz7dll9	445	17	of	of	IN
cord-023443-pvz7dll9	445	18	the	the	DT
cord-023443-pvz7dll9	445	19	examined	examine	VBN
cord-023443-pvz7dll9	445	20	S.	S.	NNP
cord-023443-pvz7dll9	445	21	pneumoniae	pneumoniae	NN
cord-023443-pvz7dll9	445	22	serotypes	serotype	NNS
cord-023443-pvz7dll9	445	23	.	.	.
cord-023443-pvz7dll9	446	1	L	l	NN
cord-023443-pvz7dll9	446	2	-	-	HYPH
cord-023443-pvz7dll9	446	3	ficolin	ficolin	NNP
cord-023443-pvz7dll9	446	4	binds	bind	VBZ
cord-023443-pvz7dll9	446	5	to	to	IN
cord-023443-pvz7dll9	446	6	some	some	DT
cord-023443-pvz7dll9	446	7	capsulated	capsulated	JJ
cord-023443-pvz7dll9	446	8	S.	S.	NNP
cord-023443-pvz7dll9	446	9	pneumoniae	pneumoniae	NN
cord-023443-pvz7dll9	446	10	serotypes	serotype	NNS
cord-023443-pvz7dll9	446	11	(	(	-LRB-
cord-023443-pvz7dll9	446	12	11A	11a	NN
cord-023443-pvz7dll9	446	13	,	,	,
cord-023443-pvz7dll9	446	14	11D	11d	CD
cord-023443-pvz7dll9	446	15	and	and	CC
cord-023443-pvz7dll9	446	16	11F	11f	CD
cord-023443-pvz7dll9	446	17	)	)	-RRB-
cord-023443-pvz7dll9	446	18	as	as	RB
cord-023443-pvz7dll9	446	19	well	well	RB
cord-023443-pvz7dll9	446	20	as	as	IN
cord-023443-pvz7dll9	446	21	some	some	DT
cord-023443-pvz7dll9	446	22	capsulated	capsulated	JJ
cord-023443-pvz7dll9	446	23	S.	S.	NNP
cord-023443-pvz7dll9	446	24	aureus	aureus	NN
cord-023443-pvz7dll9	446	25	serotypes	serotype	NNS
cord-023443-pvz7dll9	446	26	(	(	-LRB-
cord-023443-pvz7dll9	446	27	Type-1	type-1	NN
cord-023443-pvz7dll9	446	28	,	,	,
cord-023443-pvz7dll9	446	29	-8	-8	NNP
cord-023443-pvz7dll9	446	30	,	,	,
cord-023443-pvz7dll9	446	31	-9	-9	NNP
cord-023443-pvz7dll9	446	32	,	,	,
cord-023443-pvz7dll9	446	33	-11	-11	NNP
cord-023443-pvz7dll9	446	34	and	and	CC
cord-023443-pvz7dll9	446	35	-12	-12	NNP
cord-023443-pvz7dll9	446	36	)	)	-RRB-
cord-023443-pvz7dll9	446	37	.	.	.
cord-023443-pvz7dll9	447	1	H	h	NN
cord-023443-pvz7dll9	447	2	-	-	HYPH
cord-023443-pvz7dll9	447	3	ficolin	ficolin	NN
cord-023443-pvz7dll9	447	4	does	do	VBZ
cord-023443-pvz7dll9	447	5	not	not	RB
cord-023443-pvz7dll9	447	6	bind	bind	VB
cord-023443-pvz7dll9	447	7	to	to	IN
cord-023443-pvz7dll9	447	8	any	any	DT
cord-023443-pvz7dll9	447	9	of	of	IN
cord-023443-pvz7dll9	447	10	the	the	DT
cord-023443-pvz7dll9	447	11	examined	examine	VBN
cord-023443-pvz7dll9	447	12	S.	S.	NNP
cord-023443-pvz7dll9	447	13	pneumoniae	pneumoniae	NN
cord-023443-pvz7dll9	447	14	and	and	CC
cord-023443-pvz7dll9	447	15	S.	S.	NNP
cord-023443-pvz7dll9	447	16	aureus	aureus	NN
cord-023443-pvz7dll9	447	17	serotypes	serotype	NNS
cord-023443-pvz7dll9	447	18	included	include	VBN
cord-023443-pvz7dll9	447	19	in	in	IN
cord-023443-pvz7dll9	447	20	this	this	DT
cord-023443-pvz7dll9	447	21	study	study	NN
cord-023443-pvz7dll9	447	22	but	but	CC
cord-023443-pvz7dll9	447	23	did	do	VBD
cord-023443-pvz7dll9	447	24	bind	bind	VB
cord-023443-pvz7dll9	447	25	to	to	IN
cord-023443-pvz7dll9	447	26	a	a	DT
cord-023443-pvz7dll9	447	27	strain	strain	NN
cord-023443-pvz7dll9	447	28	of	of	IN
cord-023443-pvz7dll9	447	29	Aerococcus	Aerococcus	NNP
cord-023443-pvz7dll9	447	30	viridans	viridan	NNS
cord-023443-pvz7dll9	447	31	.	.	.
cord-023443-pvz7dll9	448	1	When	when	WRB
cord-023443-pvz7dll9	448	2	bound	bind	VBN
cord-023443-pvz7dll9	448	3	to	to	IN
cord-023443-pvz7dll9	448	4	bacteria	bacteria	NNS
cord-023443-pvz7dll9	448	5	,	,	,
cord-023443-pvz7dll9	448	6	MBL	MBL	NNP
cord-023443-pvz7dll9	448	7	and	and	CC
cord-023443-pvz7dll9	448	8	H	H	NNP
cord-023443-pvz7dll9	448	9	-	-	HYPH
cord-023443-pvz7dll9	448	10	ficolin	ficolin	NNP
cord-023443-pvz7dll9	448	11	initiated	initiate	VBN
cord-023443-pvz7dll9	448	12	activation	activation	NN
cord-023443-pvz7dll9	448	13	of	of	IN
cord-023443-pvz7dll9	448	14	complement	complement	NN
cord-023443-pvz7dll9	448	15	factor	factor	NN
cord-023443-pvz7dll9	448	16	C4	c4	NN
cord-023443-pvz7dll9	448	17	,	,	,
cord-023443-pvz7dll9	448	18	whereas	whereas	IN
cord-023443-pvz7dll9	448	19	L	l	NN
cord-023443-pvz7dll9	448	20	-	-	HYPH
cord-023443-pvz7dll9	448	21	ficolin	ficolin	NNP
cord-023443-pvz7dll9	448	22	did	do	VBD
cord-023443-pvz7dll9	448	23	not	not	RB
cord-023443-pvz7dll9	448	24	.	.	.
cord-023443-pvz7dll9	449	1	During	during	IN
cord-023443-pvz7dll9	449	2	this	this	DT
cord-023443-pvz7dll9	449	3	study	study	NN
cord-023443-pvz7dll9	449	4	,	,	,
cord-023443-pvz7dll9	449	5	quantitative	quantitative	JJ
cord-023443-pvz7dll9	449	6	assays	assay	NNS
cord-023443-pvz7dll9	449	7	for	for	IN
cord-023443-pvz7dll9	449	8	the	the	DT
cord-023443-pvz7dll9	449	9	three	three	CD
cord-023443-pvz7dll9	449	10	proteins	protein	NNS
cord-023443-pvz7dll9	449	11	were	be	VBD
cord-023443-pvz7dll9	449	12	developed	develop	VBN
cord-023443-pvz7dll9	449	13	and	and	CC
cord-023443-pvz7dll9	449	14	the	the	DT
cord-023443-pvz7dll9	449	15	concentration	concentration	NN
cord-023443-pvz7dll9	449	16	in	in	IN
cord-023443-pvz7dll9	449	17	97	97	CD
cord-023443-pvz7dll9	449	18	plasma	plasma	NN
cord-023443-pvz7dll9	449	19	samples	sample	NNS
cord-023443-pvz7dll9	449	20	were	be	VBD
cord-023443-pvz7dll9	449	21	determined	determine	VBN
cord-023443-pvz7dll9	449	22	and	and	CC
cord-023443-pvz7dll9	449	23	the	the	DT
cord-023443-pvz7dll9	449	24	median	median	JJ
cord-023443-pvz7dll9	449	25	values	value	NNS
cord-023443-pvz7dll9	449	26	were	be	VBD
cord-023443-pvz7dll9	449	27	estimated	estimate	VBN
cord-023443-pvz7dll9	449	28	at	at	IN
cord-023443-pvz7dll9	449	29	0.8	0.8	CD
cord-023443-pvz7dll9	449	30	mg	mg	NN
cord-023443-pvz7dll9	449	31	of	of	IN
cord-023443-pvz7dll9	449	32	MBL	MBL	NNP
cord-023443-pvz7dll9	449	33	/	/	SYM
cord-023443-pvz7dll9	449	34	ml	ml	NNS
cord-023443-pvz7dll9	449	35	,	,	,
cord-023443-pvz7dll9	449	36	3.3	3.3	CD
cord-023443-pvz7dll9	449	37	mg	mg	NN
cord-023443-pvz7dll9	449	38	of	of	IN
cord-023443-pvz7dll9	449	39	L	L	NNP
cord-023443-pvz7dll9	449	40	-	-	HYPH
cord-023443-pvz7dll9	449	41	ficolin	ficolin	NNP
cord-023443-pvz7dll9	449	42	/	/	SYM
cord-023443-pvz7dll9	449	43	ml	ml	NN
cord-023443-pvz7dll9	449	44	and	and	CC
cord-023443-pvz7dll9	449	45	18.4	18.4	CD
cord-023443-pvz7dll9	449	46	mg	mg	NNS
cord-023443-pvz7dll9	449	47	of	of	IN
cord-023443-pvz7dll9	449	48	H	H	NNP
cord-023443-pvz7dll9	449	49	-	-	HYPH
cord-023443-pvz7dll9	449	50	ficolin/	ficolin/	NNP
cord-023443-pvz7dll9	449	51	ml	ml	NN
cord-023443-pvz7dll9	449	52	,	,	,
cord-023443-pvz7dll9	449	53	respectively	respectively	RB
cord-023443-pvz7dll9	449	54	.	.	.
cord-023443-pvz7dll9	450	1	The	the	DT
cord-023443-pvz7dll9	450	2	absence	absence	NN
cord-023443-pvz7dll9	450	3	of	of	IN
cord-023443-pvz7dll9	450	4	early	early	JJ
cord-023443-pvz7dll9	450	5	complement	complement	NN
cord-023443-pvz7dll9	450	6	components	component	NNS
cord-023443-pvz7dll9	450	7	(	(	-LRB-
cord-023443-pvz7dll9	450	8	C1	C1	NNP
cord-023443-pvz7dll9	450	9	,	,	,
cord-023443-pvz7dll9	450	10	C4	C4	NNP
cord-023443-pvz7dll9	450	11	and	and	CC
cord-023443-pvz7dll9	450	12	C2	C2	NNP
cord-023443-pvz7dll9	450	13	but	but	CC
cord-023443-pvz7dll9	450	14	not	not	RB
cord-023443-pvz7dll9	450	15	C3	C3	NNP
cord-023443-pvz7dll9	450	16	)	)	-RRB-
cord-023443-pvz7dll9	450	17	is	be	VBZ
cord-023443-pvz7dll9	450	18	a	a	DT
cord-023443-pvz7dll9	450	19	predisposing	predisposing	JJ
cord-023443-pvz7dll9	450	20	factor	factor	NN
cord-023443-pvz7dll9	450	21	for	for	IN
cord-023443-pvz7dll9	450	22	systemic	systemic	JJ
cord-023443-pvz7dll9	450	23	lupus	lupus	NN
cord-023443-pvz7dll9	450	24	erythematosus	erythematosus	NN
cord-023443-pvz7dll9	450	25	(	(	-LRB-
cord-023443-pvz7dll9	450	26	SLE	SLE	NNP
cord-023443-pvz7dll9	450	27	)	)	-RRB-
cord-023443-pvz7dll9	450	28	.	.	.
cord-023443-pvz7dll9	451	1	Recently	recently	RB
cord-023443-pvz7dll9	451	2	,	,	,
cord-023443-pvz7dll9	451	3	we	-PRON-	PRP
cord-023443-pvz7dll9	451	4	demonstrated	demonstrate	VBD
cord-023443-pvz7dll9	451	5	that	that	IN
cord-023443-pvz7dll9	451	6	,	,	,
cord-023443-pvz7dll9	451	7	in	in	IN
cord-023443-pvz7dll9	451	8	C4-deficient	c4-deficient	NN
cord-023443-pvz7dll9	451	9	(	(	-LRB-
cord-023443-pvz7dll9	451	10	C4	C4	NNP
cord-023443-pvz7dll9	451	11	def	def	NN
cord-023443-pvz7dll9	451	12	.	.	.
cord-023443-pvz7dll9	451	13	)	)	-RRB-
cord-023443-pvz7dll9	452	1	mice	mouse	NNS
cord-023443-pvz7dll9	452	2	,	,	,
cord-023443-pvz7dll9	452	3	IgM	igm	NN
cord-023443-pvz7dll9	452	4	-	-	HYPH
cord-023443-pvz7dll9	452	5	containing	contain	VBG
cord-023443-pvz7dll9	452	6	immune	immune	JJ
cord-023443-pvz7dll9	452	7	complexes	complex	NNS
cord-023443-pvz7dll9	452	8	(	(	-LRB-
cord-023443-pvz7dll9	452	9	IgM	IgM	NNP
cord-023443-pvz7dll9	452	10	-	-	HYPH
cord-023443-pvz7dll9	452	11	IC	IC	NNP
cord-023443-pvz7dll9	452	12	)	)	-RRB-
cord-023443-pvz7dll9	452	13	are	be	VBP
cord-023443-pvz7dll9	452	14	filtered	filter	VBN
cord-023443-pvz7dll9	452	15	by	by	IN
cord-023443-pvz7dll9	452	16	the	the	DT
cord-023443-pvz7dll9	452	17	splenic	splenic	JJ
cord-023443-pvz7dll9	452	18	barrier	barrier	NN
cord-023443-pvz7dll9	452	19	of	of	IN
cord-023443-pvz7dll9	452	20	marginal	marginal	JJ
cord-023443-pvz7dll9	452	21	zone	zone	NN
cord-023443-pvz7dll9	452	22	macrophages	macrophage	NNS
cord-023443-pvz7dll9	452	23	(	(	-LRB-
cord-023443-pvz7dll9	452	24	MZM	MZM	NNP
cord-023443-pvz7dll9	452	25	)	)	-RRB-
cord-023443-pvz7dll9	452	26	,	,	,
cord-023443-pvz7dll9	452	27	resulting	result	VBG
cord-023443-pvz7dll9	452	28	in	in	IN
cord-023443-pvz7dll9	452	29	an	an	DT
cord-023443-pvz7dll9	452	30	increased	increase	VBN
cord-023443-pvz7dll9	452	31	immune	immune	JJ
cord-023443-pvz7dll9	452	32	response	response	NN
cord-023443-pvz7dll9	452	33	against	against	IN
cord-023443-pvz7dll9	452	34	antigens	antigen	NNS
cord-023443-pvz7dll9	452	35	within	within	IN
cord-023443-pvz7dll9	452	36	these	these	DT
cord-023443-pvz7dll9	452	37	IgM	IgM	NNP
cord-023443-pvz7dll9	452	38	-	-	HYPH
cord-023443-pvz7dll9	452	39	IC	IC	NNP
cord-023443-pvz7dll9	452	40	,	,	,
cord-023443-pvz7dll9	452	41	but	but	CC
cord-023443-pvz7dll9	452	42	this	this	DT
cord-023443-pvz7dll9	452	43	could	could	MD
cord-023443-pvz7dll9	452	44	not	not	RB
cord-023443-pvz7dll9	452	45	be	be	VB
cord-023443-pvz7dll9	452	46	observed	observe	VBN
cord-023443-pvz7dll9	452	47	in	in	IN
cord-023443-pvz7dll9	452	48	wildtype	wildtype	NN
cord-023443-pvz7dll9	452	49	or	or	CC
cord-023443-pvz7dll9	452	50	C3	c3	NN
cord-023443-pvz7dll9	452	51	def	def	NN
cord-023443-pvz7dll9	452	52	.	.	.
cord-023443-pvz7dll9	453	1	mice	mouse	NNS
cord-023443-pvz7dll9	453	2	.	.	.
cord-023443-pvz7dll9	454	1	We	-PRON-	PRP
cord-023443-pvz7dll9	454	2	hypothesized	hypothesize	VBD
cord-023443-pvz7dll9	454	3	that	that	IN
cord-023443-pvz7dll9	454	4	splenic	splenic	JJ
cord-023443-pvz7dll9	454	5	CD11b	CD11b	NNS
cord-023443-pvz7dll9	454	6	þ	þ	CD
cord-023443-pvz7dll9	454	7	MZM	MZM	NNP
cord-023443-pvz7dll9	454	8	play	play	VBP
cord-023443-pvz7dll9	454	9	an	an	DT
cord-023443-pvz7dll9	454	10	important	important	JJ
cord-023443-pvz7dll9	454	11	role	role	NN
cord-023443-pvz7dll9	454	12	in	in	IN
cord-023443-pvz7dll9	454	13	the	the	DT
cord-023443-pvz7dll9	454	14	induction	induction	NN
cord-023443-pvz7dll9	454	15	of	of	IN
cord-023443-pvz7dll9	454	16	autoimmunity	autoimmunity	NN
cord-023443-pvz7dll9	454	17	,	,	,
cord-023443-pvz7dll9	454	18	and	and	CC
cord-023443-pvz7dll9	454	19	we	-PRON-	PRP
cord-023443-pvz7dll9	454	20	therefore	therefore	RB
cord-023443-pvz7dll9	454	21	analysed	analyse	VBD
cord-023443-pvz7dll9	454	22	their	-PRON-	PRP$
cord-023443-pvz7dll9	454	23	cytokine	cytokine	NN
cord-023443-pvz7dll9	454	24	profile	profile	NN
cord-023443-pvz7dll9	454	25	after	after	IN
cord-023443-pvz7dll9	454	26	isolation	isolation	NN
cord-023443-pvz7dll9	454	27	with	with	IN
cord-023443-pvz7dll9	454	28	the	the	DT
cord-023443-pvz7dll9	454	29	help	help	NN
cord-023443-pvz7dll9	454	30	of	of	IN
cord-023443-pvz7dll9	454	31	magnetic	magnetic	JJ
cord-023443-pvz7dll9	454	32	antibody	antibody	NN
cord-023443-pvz7dll9	454	33	cell	cell	NN
cord-023443-pvz7dll9	454	34	sorting	sorting	NN
cord-023443-pvz7dll9	454	35	.	.	.
cord-023443-pvz7dll9	455	1	mRNA	mRNA	NNP
cord-023443-pvz7dll9	455	2	was	be	VBD
cord-023443-pvz7dll9	455	3	isolated	isolate	VBN
cord-023443-pvz7dll9	455	4	,	,	,
cord-023443-pvz7dll9	455	5	and	and	CC
cord-023443-pvz7dll9	455	6	real	real	JJ
cord-023443-pvz7dll9	455	7	-	-	HYPH
cord-023443-pvz7dll9	455	8	time	time	NN
cord-023443-pvz7dll9	455	9	PCR	PCR	NNP
cord-023443-pvz7dll9	455	10	was	be	VBD
cord-023443-pvz7dll9	455	11	performed	perform	VBN
cord-023443-pvz7dll9	455	12	with	with	IN
cord-023443-pvz7dll9	455	13	specific	specific	JJ
cord-023443-pvz7dll9	455	14	primers	primer	NNS
cord-023443-pvz7dll9	455	15	for	for	IN
cord-023443-pvz7dll9	455	16	murine	murine	JJ
cord-023443-pvz7dll9	455	17	IFN	IFN	NNP
cord-023443-pvz7dll9	455	18	-	-	HYPH
cord-023443-pvz7dll9	455	19	g	g	NNP
cord-023443-pvz7dll9	455	20	(	(	-LRB-
cord-023443-pvz7dll9	455	21	IFN	IFN	NNP
cord-023443-pvz7dll9	455	22	-	-	HYPH
cord-023443-pvz7dll9	455	23	g	g	NNP
cord-023443-pvz7dll9	455	24	)	)	-RRB-
cord-023443-pvz7dll9	455	25	,	,	,
cord-023443-pvz7dll9	455	26	interleukin-12	interleukin-12	XX
cord-023443-pvz7dll9	455	27	(	(	-LRB-
cord-023443-pvz7dll9	455	28	IL-12	IL-12	NNP
cord-023443-pvz7dll9	455	29	)	)	-RRB-
cord-023443-pvz7dll9	455	30	and	and	CC
cord-023443-pvz7dll9	455	31	IFN	IFN	NNP
cord-023443-pvz7dll9	455	32	-	-	HYPH
cord-023443-pvz7dll9	455	33	a	a	NNP
cord-023443-pvz7dll9	455	34	(	(	-LRB-
cord-023443-pvz7dll9	455	35	IFN	IFN	NNP
cord-023443-pvz7dll9	455	36	-	-	HYPH
cord-023443-pvz7dll9	455	37	a	a	NN
cord-023443-pvz7dll9	455	38	)	)	-RRB-
cord-023443-pvz7dll9	455	39	.	.	.
cord-023443-pvz7dll9	456	1	We	-PRON-	PRP
cord-023443-pvz7dll9	456	2	observe	observe	VBP
cord-023443-pvz7dll9	456	3	a	a	DT
cord-023443-pvz7dll9	456	4	moderate	moderate	JJ
cord-023443-pvz7dll9	456	5	increase	increase	NN
cord-023443-pvz7dll9	456	6	of	of	IN
cord-023443-pvz7dll9	456	7	IL-12	IL-12	NNP
cord-023443-pvz7dll9	456	8	and	and	CC
cord-023443-pvz7dll9	456	9	IFN	IFN	NNP
cord-023443-pvz7dll9	456	10	-	-	HYPH
cord-023443-pvz7dll9	456	11	g	g	NNP
cord-023443-pvz7dll9	456	12	mRNA	mrna	NN
cord-023443-pvz7dll9	457	1	in	in	IN
cord-023443-pvz7dll9	458	1	CD11b	CD11b	NNPS
cord-023443-pvz7dll9	458	2	þ	þ	NNP
cord-023443-pvz7dll9	458	3	cells	cell	NNS
cord-023443-pvz7dll9	458	4	of	of	IN
cord-023443-pvz7dll9	458	5	C4	c4	NN
cord-023443-pvz7dll9	458	6	def	def	NN
cord-023443-pvz7dll9	458	7	.	.	.
cord-023443-pvz7dll9	459	1	mice	mouse	NNS
cord-023443-pvz7dll9	459	2	compared	compare	VBN
cord-023443-pvz7dll9	459	3	to	to	IN
cord-023443-pvz7dll9	459	4	wildtype	wildtype	NN
cord-023443-pvz7dll9	459	5	cells	cell	NNS
cord-023443-pvz7dll9	459	6	.	.	.
cord-023443-pvz7dll9	460	1	Surprisingly	surprisingly	RB
cord-023443-pvz7dll9	460	2	,	,	,
cord-023443-pvz7dll9	460	3	the	the	DT
cord-023443-pvz7dll9	460	4	concentration	concentration	NN
cord-023443-pvz7dll9	460	5	of	of	IN
cord-023443-pvz7dll9	460	6	IFN	IFN	NNP
cord-023443-pvz7dll9	460	7	-	-	:
cord-023443-pvz7dll9	460	8	a	a	DT
cord-023443-pvz7dll9	460	9	mRNA	mrna	NN
cord-023443-pvz7dll9	460	10	is	be	VBZ
cord-023443-pvz7dll9	460	11	six	six	CD
cord-023443-pvz7dll9	460	12	times	time	NNS
cord-023443-pvz7dll9	460	13	higher	high	JJR
cord-023443-pvz7dll9	460	14	in	in	IN
cord-023443-pvz7dll9	460	15	C4	c4	NN
cord-023443-pvz7dll9	460	16	def	def	NN
cord-023443-pvz7dll9	460	17	.	.	.
cord-023443-pvz7dll9	461	1	mice	mouse	NNS
cord-023443-pvz7dll9	461	2	.	.	.
cord-023443-pvz7dll9	462	1	Preliminary	preliminary	JJ
cord-023443-pvz7dll9	462	2	results	result	NNS
cord-023443-pvz7dll9	462	3	suggest	suggest	VBP
cord-023443-pvz7dll9	462	4	that	that	IN
cord-023443-pvz7dll9	462	5	mRNA	mrna	NN
cord-023443-pvz7dll9	462	6	in	in	IN
cord-023443-pvz7dll9	462	7	CD11b	CD11b	NNS
cord-023443-pvz7dll9	462	8	þ	þ	NNP
cord-023443-pvz7dll9	462	9	cells	cell	NNS
cord-023443-pvz7dll9	462	10	of	of	IN
cord-023443-pvz7dll9	462	11	C3	c3	NN
cord-023443-pvz7dll9	462	12	def	def	NN
cord-023443-pvz7dll9	462	13	.	.	.
cord-023443-pvz7dll9	463	1	mice	mice	NN
cord-023443-pvz7dll9	463	2	is	be	VBZ
cord-023443-pvz7dll9	463	3	even	even	RB
cord-023443-pvz7dll9	463	4	lower	low	JJR
cord-023443-pvz7dll9	463	5	than	than	IN
cord-023443-pvz7dll9	463	6	that	that	DT
cord-023443-pvz7dll9	463	7	in	in	IN
cord-023443-pvz7dll9	463	8	wt	wt	NN
cord-023443-pvz7dll9	463	9	.	.	.
cord-023443-pvz7dll9	464	1	Six	six	CD
cord-023443-pvz7dll9	464	2	hours	hour	NNS
cord-023443-pvz7dll9	464	3	following	follow	VBG
cord-023443-pvz7dll9	464	4	i.v	i.v	NNP
cord-023443-pvz7dll9	464	5	.	.	NNP
cord-023443-pvz7dll9	464	6	application	application	NN
cord-023443-pvz7dll9	464	7	of	of	IN
cord-023443-pvz7dll9	464	8	20	20	CD
cord-023443-pvz7dll9	464	9	mg	mg	NNS
cord-023443-pvz7dll9	464	10	of	of	IN
cord-023443-pvz7dll9	464	11	a	a	DT
cord-023443-pvz7dll9	464	12	Abstracts	Abstracts	NNPS
cord-023443-pvz7dll9	464	13	625	625	CD
cord-023443-pvz7dll9	464	14	..................................................................................................................................................................................................	..................................................................................................................................................................................................	.
cord-023443-pvz7dll9	465	1	murine	murine	JJ
cord-023443-pvz7dll9	465	2	monoclonal	monoclonal	NNP
cord-023443-pvz7dll9	465	3	IgM	IgM	NNP
cord-023443-pvz7dll9	465	4	anti	anti	JJ
cord-023443-pvz7dll9	465	5	-	-	JJ
cord-023443-pvz7dll9	465	6	dsDNA	dsdna	JJ
cord-023443-pvz7dll9	465	7	antibody	antibody	NN
cord-023443-pvz7dll9	465	8	,	,	,
cord-023443-pvz7dll9	465	9	production	production	NN
cord-023443-pvz7dll9	465	10	of	of	IN
cord-023443-pvz7dll9	465	11	IL-12	IL-12	NNP
cord-023443-pvz7dll9	465	12	,	,	,
cord-023443-pvz7dll9	465	13	IFN	IFN	NNP
cord-023443-pvz7dll9	465	14	-	-	HYPH
cord-023443-pvz7dll9	465	15	g	g	NNP
cord-023443-pvz7dll9	465	16	and	and	CC
cord-023443-pvz7dll9	465	17	IFN-	IFN-	NNP
cord-023443-pvz7dll9	466	1	a	a	DT
cord-023443-pvz7dll9	466	2	mRNA	mrna	NN
cord-023443-pvz7dll9	466	3	is	be	VBZ
cord-023443-pvz7dll9	466	4	increased	increase	VBN
cord-023443-pvz7dll9	466	5	in	in	IN
cord-023443-pvz7dll9	466	6	CD11b	CD11b	NNS
cord-023443-pvz7dll9	466	7	þ	þ	NNP
cord-023443-pvz7dll9	466	8	cells	cell	NNS
cord-023443-pvz7dll9	466	9	of	of	IN
cord-023443-pvz7dll9	466	10	both	both	DT
cord-023443-pvz7dll9	466	11	C4	c4	NN
cord-023443-pvz7dll9	466	12	def	def	NN
cord-023443-pvz7dll9	466	13	.	.	.
cord-023443-pvz7dll9	467	1	and	and	CC
cord-023443-pvz7dll9	467	2	wt	wt	NN
cord-023443-pvz7dll9	467	3	mice	mouse	NNS
cord-023443-pvz7dll9	467	4	.	.	.
cord-023443-pvz7dll9	468	1	Several	several	JJ
cord-023443-pvz7dll9	468	2	references	reference	NNS
cord-023443-pvz7dll9	468	3	described	describe	VBN
cord-023443-pvz7dll9	468	4	increased	increase	VBN
cord-023443-pvz7dll9	468	5	levels	level	NNS
cord-023443-pvz7dll9	468	6	of	of	IN
cord-023443-pvz7dll9	468	7	INF	inf	NN
cord-023443-pvz7dll9	468	8	-	-	,
cord-023443-pvz7dll9	468	9	a	a	NN
cord-023443-pvz7dll9	468	10	in	in	IN
cord-023443-pvz7dll9	468	11	patients	patient	NNS
cord-023443-pvz7dll9	468	12	with	with	IN
cord-023443-pvz7dll9	468	13	SLE	SLE	NNP
cord-023443-pvz7dll9	468	14	.	.	.
cord-023443-pvz7dll9	469	1	Dendritic	dendritic	JJ
cord-023443-pvz7dll9	469	2	cells	cell	NNS
cord-023443-pvz7dll9	469	3	are	be	VBP
cord-023443-pvz7dll9	469	4	discussed	discuss	VBN
cord-023443-pvz7dll9	469	5	as	as	IN
cord-023443-pvz7dll9	469	6	a	a	DT
cord-023443-pvz7dll9	469	7	major	major	JJ
cord-023443-pvz7dll9	469	8	source	source	NN
cord-023443-pvz7dll9	469	9	of	of	IN
cord-023443-pvz7dll9	469	10	IFN	IFN	NNP
cord-023443-pvz7dll9	469	11	-	-	HYPH
cord-023443-pvz7dll9	469	12	a	a	NN
cord-023443-pvz7dll9	469	13	.	.	.
cord-023443-pvz7dll9	470	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	470	2	observation	observation	NN
cord-023443-pvz7dll9	470	3	that	that	IN
cord-023443-pvz7dll9	470	4	C4-deficient	c4-deficient	NN
cord-023443-pvz7dll9	470	5	,	,	,
cord-023443-pvz7dll9	470	6	SLE	sle	NN
cord-023443-pvz7dll9	470	7	-	-	HYPH
cord-023443-pvz7dll9	470	8	susceptible	susceptible	JJ
cord-023443-pvz7dll9	470	9	mice	mouse	NNS
cord-023443-pvz7dll9	470	10	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	470	11	an	an	DT
cord-023443-pvz7dll9	470	12	increased	increase	VBN
cord-023443-pvz7dll9	470	13	spontaneous	spontaneous	JJ
cord-023443-pvz7dll9	470	14	IFN	IFN	NNP
cord-023443-pvz7dll9	470	15	-	-	:
cord-023443-pvz7dll9	470	16	a	a	DT
cord-023443-pvz7dll9	470	17	production	production	NN
cord-023443-pvz7dll9	470	18	by	by	IN
cord-023443-pvz7dll9	470	19	splenic	splenic	JJ
cord-023443-pvz7dll9	470	20	CD11b	CD11b	NNPS
cord-023443-pvz7dll9	470	21	þ	þ	NNP
cord-023443-pvz7dll9	470	22	marginal	marginal	JJ
cord-023443-pvz7dll9	470	23	zone	zone	NN
cord-023443-pvz7dll9	470	24	macrophages	macrophage	NNS
cord-023443-pvz7dll9	470	25	could	could	MD
cord-023443-pvz7dll9	470	26	be	be	VB
cord-023443-pvz7dll9	470	27	an	an	DT
cord-023443-pvz7dll9	470	28	early	early	JJ
cord-023443-pvz7dll9	470	29	sign	sign	NN
cord-023443-pvz7dll9	470	30	and	and	CC
cord-023443-pvz7dll9	470	31	a	a	DT
cord-023443-pvz7dll9	470	32	trigger	trigger	NN
cord-023443-pvz7dll9	470	33	for	for	IN
cord-023443-pvz7dll9	470	34	the	the	DT
cord-023443-pvz7dll9	470	35	development	development	NN
cord-023443-pvz7dll9	470	36	of	of	IN
cord-023443-pvz7dll9	470	37	SLE	SLE	NNP
cord-023443-pvz7dll9	470	38	.	.	.
cord-023443-pvz7dll9	471	1	This	this	DT
cord-023443-pvz7dll9	471	2	is	be	VBZ
cord-023443-pvz7dll9	471	3	supported	support	VBN
cord-023443-pvz7dll9	471	4	by	by	IN
cord-023443-pvz7dll9	471	5	the	the	DT
cord-023443-pvz7dll9	471	6	fact	fact	NN
cord-023443-pvz7dll9	471	7	that	that	IN
cord-023443-pvz7dll9	471	8	the	the	DT
cord-023443-pvz7dll9	471	9	absence	absence	NN
cord-023443-pvz7dll9	471	10	of	of	IN
cord-023443-pvz7dll9	471	11	C3	C3	NNP
cord-023443-pvz7dll9	471	12	is	be	VBZ
cord-023443-pvz7dll9	471	13	not	not	RB
cord-023443-pvz7dll9	471	14	a	a	DT
cord-023443-pvz7dll9	471	15	predisposing	predisposing	JJ
cord-023443-pvz7dll9	471	16	factor	factor	NN
cord-023443-pvz7dll9	471	17	for	for	IN
cord-023443-pvz7dll9	471	18	SLE	SLE	NNP
cord-023443-pvz7dll9	471	19	and	and	CC
cord-023443-pvz7dll9	471	20	our	-PRON-	PRP$
cord-023443-pvz7dll9	471	21	observation	observation	NN
cord-023443-pvz7dll9	471	22	that	that	IN
cord-023443-pvz7dll9	471	23	C3	c3	NN
cord-023443-pvz7dll9	471	24	def	def	NN
cord-023443-pvz7dll9	471	25	.	.	.
cord-023443-pvz7dll9	472	1	animals	animal	NNS
cord-023443-pvz7dll9	472	2	display	display	VBP
cord-023443-pvz7dll9	472	3	low	low	JJ
cord-023443-pvz7dll9	472	4	levels	level	NNS
cord-023443-pvz7dll9	472	5	of	of	IN
cord-023443-pvz7dll9	472	6	IFN	IFN	NNP
cord-023443-pvz7dll9	472	7	-	-	:
cord-023443-pvz7dll9	472	8	a	a	DT
cord-023443-pvz7dll9	472	9	mRNA	mrna	NN
cord-023443-pvz7dll9	472	10	.	.	.
cord-023443-pvz7dll9	472	11	 	 	_SP
cord-023443-pvz7dll9	473	1	200	200	CD
cord-023443-pvz7dll9	473	2	-	-	SYM
cord-023443-pvz7dll9	473	3	400	400	CD
cord-023443-pvz7dll9	473	4	million	million	CD
cord-023443-pvz7dll9	473	5	people	people	NNS
cord-023443-pvz7dll9	473	6	worldwide	worldwide	RB
cord-023443-pvz7dll9	473	7	and	and	CC
cord-023443-pvz7dll9	473	8	represents	represent	VBZ
cord-023443-pvz7dll9	473	9	one	one	CD
cord-023443-pvz7dll9	473	10	of	of	IN
cord-023443-pvz7dll9	473	11	the	the	DT
cord-023443-pvz7dll9	473	12	leading	lead	VBG
cord-023443-pvz7dll9	473	13	causes	cause	NNS
cord-023443-pvz7dll9	473	14	for	for	IN
cord-023443-pvz7dll9	473	15	liver	liver	NN
cord-023443-pvz7dll9	473	16	cirrhosis	cirrhosis	NN
cord-023443-pvz7dll9	473	17	and	and	CC
cord-023443-pvz7dll9	473	18	hepatocellular	hepatocellular	JJ
cord-023443-pvz7dll9	473	19	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	473	20	.	.	.
cord-023443-pvz7dll9	474	1	Control	control	NN
cord-023443-pvz7dll9	474	2	over	over	IN
cord-023443-pvz7dll9	474	3	the	the	DT
cord-023443-pvz7dll9	474	4	HBV	HBV	NNP
cord-023443-pvz7dll9	474	5	infection	infection	NN
cord-023443-pvz7dll9	474	6	is	be	VBZ
cord-023443-pvz7dll9	474	7	achieved	achieve	VBN
cord-023443-pvz7dll9	474	8	mainly	mainly	RB
cord-023443-pvz7dll9	474	9	by	by	IN
cord-023443-pvz7dll9	474	10	vaccination	vaccination	NN
cord-023443-pvz7dll9	474	11	with	with	IN
cord-023443-pvz7dll9	474	12	Hepatitis	Hepatitis	NNP
cord-023443-pvz7dll9	474	13	B	B	NNP
cord-023443-pvz7dll9	474	14	surface	surface	NN
cord-023443-pvz7dll9	474	15	antigen	antigen	NN
cord-023443-pvz7dll9	474	16	(	(	-LRB-
cord-023443-pvz7dll9	474	17	HBsAg	hbsag	ADD
cord-023443-pvz7dll9	474	18	)	)	-RRB-
cord-023443-pvz7dll9	474	19	.	.	.
cord-023443-pvz7dll9	475	1	HBsAg	HBsAg	NNP
cord-023443-pvz7dll9	475	2	contains	contain	VBZ
cord-023443-pvz7dll9	475	3	N	n	CD
cord-023443-pvz7dll9	475	4	-	-	HYPH
cord-023443-pvz7dll9	475	5	linked	link	VBN
cord-023443-pvz7dll9	475	6	glycosylation	glycosylation	NN
cord-023443-pvz7dll9	475	7	side	side	NN
cord-023443-pvz7dll9	475	8	and	and	CC
cord-023443-pvz7dll9	475	9	is	be	VBZ
cord-023443-pvz7dll9	475	10	recognized	recognize	VBN
cord-023443-pvz7dll9	475	11	by	by	IN
cord-023443-pvz7dll9	475	12	both	both	DT
cord-023443-pvz7dll9	475	13	MBL	MBL	NNP
cord-023443-pvz7dll9	475	14	-	-	HYPH
cord-023443-pvz7dll9	475	15	A	A	NNP
cord-023443-pvz7dll9	475	16	and	and	CC
cord-023443-pvz7dll9	475	17	MBL	MBL	NNP
cord-023443-pvz7dll9	475	18	-	-	HYPH
cord-023443-pvz7dll9	475	19	C	C	NNP
cord-023443-pvz7dll9	475	20	in	in	IN
cord-023443-pvz7dll9	475	21	a	a	DT
cord-023443-pvz7dll9	475	22	Cadependent	Cadependent	NNP
cord-023443-pvz7dll9	475	23	manner	manner	NN
cord-023443-pvz7dll9	475	24	.	.	.
cord-023443-pvz7dll9	476	1	HbsAg	HbsAg	NNP
cord-023443-pvz7dll9	476	2	-	-	HYPH
cord-023443-pvz7dll9	476	3	MBL	MBL	NNP
cord-023443-pvz7dll9	476	4	complexes	complex	NNS
cord-023443-pvz7dll9	476	5	activate	activate	VBP
cord-023443-pvz7dll9	476	6	complement	complement	NN
cord-023443-pvz7dll9	476	7	and	and	CC
cord-023443-pvz7dll9	476	8	may	may	MD
cord-023443-pvz7dll9	476	9	thus	thus	RB
cord-023443-pvz7dll9	476	10	affect	affect	VB
cord-023443-pvz7dll9	476	11	humoural	humoural	JJ
cord-023443-pvz7dll9	476	12	immunity	immunity	NN
cord-023443-pvz7dll9	476	13	.	.	.
cord-023443-pvz7dll9	477	1	To	to	TO
cord-023443-pvz7dll9	477	2	investigate	investigate	VB
cord-023443-pvz7dll9	477	3	the	the	DT
cord-023443-pvz7dll9	477	4	role	role	NN
cord-023443-pvz7dll9	477	5	of	of	IN
cord-023443-pvz7dll9	477	6	MBL	MBL	NNP
cord-023443-pvz7dll9	477	7	in	in	IN
cord-023443-pvz7dll9	477	8	humoural	humoural	NNP
cord-023443-pvz7dll9	477	9	responses	response	NNS
cord-023443-pvz7dll9	477	10	to	to	IN
cord-023443-pvz7dll9	477	11	HBsAg	hbsag	ADD
cord-023443-pvz7dll9	477	12	,	,	,
cord-023443-pvz7dll9	477	13	we	-PRON-	PRP
cord-023443-pvz7dll9	477	14	immununized	immununize	VBD
cord-023443-pvz7dll9	477	15	mice	mouse	NNS
cord-023443-pvz7dll9	477	16	that	that	WDT
cord-023443-pvz7dll9	477	17	lack	lack	VBP
cord-023443-pvz7dll9	477	18	both	both	DT
cord-023443-pvz7dll9	477	19	MBL	MBL	NNP
cord-023443-pvz7dll9	477	20	-	-	HYPH
cord-023443-pvz7dll9	477	21	A	A	NNP
cord-023443-pvz7dll9	477	22	and	and	CC
cord-023443-pvz7dll9	477	23	MBL	MBL	NNP
cord-023443-pvz7dll9	477	24	-	-	HYPH
cord-023443-pvz7dll9	477	25	C	c	NN
cord-023443-pvz7dll9	477	26	proteins	protein	NNS
cord-023443-pvz7dll9	477	27	with	with	IN
cord-023443-pvz7dll9	477	28	soluble	soluble	JJ
cord-023443-pvz7dll9	477	29	HBsAg	hbsag	ADD
cord-023443-pvz7dll9	477	30	.	.	.
cord-023443-pvz7dll9	478	1	It	-PRON-	PRP
cord-023443-pvz7dll9	478	2	has	have	VBZ
cord-023443-pvz7dll9	478	3	been	be	VBN
cord-023443-pvz7dll9	478	4	shown	show	VBN
cord-023443-pvz7dll9	478	5	that	that	IN
cord-023443-pvz7dll9	478	6	deficiencies	deficiency	NNS
cord-023443-pvz7dll9	478	7	in	in	IN
cord-023443-pvz7dll9	478	8	other	other	JJ
cord-023443-pvz7dll9	478	9	complement	complement	NN
cord-023443-pvz7dll9	478	10	components	component	NNS
cord-023443-pvz7dll9	478	11	like	like	IN
cord-023443-pvz7dll9	478	12	C1q	C1q	NNP
cord-023443-pvz7dll9	478	13	,	,	,
cord-023443-pvz7dll9	478	14	C4	C4	NNP
cord-023443-pvz7dll9	478	15	and	and	CC
cord-023443-pvz7dll9	478	16	C3	c3	NN
cord-023443-pvz7dll9	478	17	result	result	NN
cord-023443-pvz7dll9	478	18	in	in	IN
cord-023443-pvz7dll9	478	19	decreased	decrease	VBN
cord-023443-pvz7dll9	478	20	antibody	antibody	NN
cord-023443-pvz7dll9	478	21	responses	response	NNS
cord-023443-pvz7dll9	478	22	.	.	.
cord-023443-pvz7dll9	479	1	However	however	RB
cord-023443-pvz7dll9	479	2	,	,	,
cord-023443-pvz7dll9	479	3	MBL	MBL	NNP
cord-023443-pvz7dll9	479	4	double	double	JJ
cord-023443-pvz7dll9	479	5	KO	KO	NNP
cord-023443-pvz7dll9	479	6	animals	animal	NNS
cord-023443-pvz7dll9	479	7	mounted	mount	VBD
cord-023443-pvz7dll9	479	8	dramatically	dramatically	RB
cord-023443-pvz7dll9	479	9	increased	increase	VBN
cord-023443-pvz7dll9	479	10	humoural	humoural	JJ
cord-023443-pvz7dll9	479	11	responses	response	NNS
cord-023443-pvz7dll9	479	12	.	.	.
cord-023443-pvz7dll9	480	1	After	after	IN
cord-023443-pvz7dll9	480	2	priming	prime	VBG
cord-023443-pvz7dll9	480	3	,	,	,
cord-023443-pvz7dll9	480	4	MBL	MBL	NNP
cord-023443-pvz7dll9	480	5	double	double	JJ
cord-023443-pvz7dll9	480	6	KOs	KOs	NNP
cord-023443-pvz7dll9	480	7	mounted	mount	VBD
cord-023443-pvz7dll9	480	8	HbsAg	HbsAg	NNP
cord-023443-pvz7dll9	480	9	-	-	HYPH
cord-023443-pvz7dll9	480	10	specific	specific	JJ
cord-023443-pvz7dll9	480	11	IgM	IgM	NNP
cord-023443-pvz7dll9	480	12	responses	response	NNS
cord-023443-pvz7dll9	480	13	,	,	,
cord-023443-pvz7dll9	480	14	which	which	WDT
cord-023443-pvz7dll9	480	15	were	be	VBD
cord-023443-pvz7dll9	480	16	threefold	threefold	RB
cord-023443-pvz7dll9	480	17	higher	high	JJR
cord-023443-pvz7dll9	480	18	than	than	IN
cord-023443-pvz7dll9	480	19	WT	WT	NNP
cord-023443-pvz7dll9	480	20	controls	control	NNS
cord-023443-pvz7dll9	480	21	.	.	.
cord-023443-pvz7dll9	481	1	After	after	IN
cord-023443-pvz7dll9	481	2	boosting	boost	VBG
cord-023443-pvz7dll9	481	3	the	the	DT
cord-023443-pvz7dll9	481	4	HBsAg	hbsag	XX
cord-023443-pvz7dll9	481	5	,	,	,
cord-023443-pvz7dll9	481	6	total	total	JJ
cord-023443-pvz7dll9	481	7	IgG	igg	NN
cord-023443-pvz7dll9	481	8	was	be	VBD
cord-023443-pvz7dll9	481	9	10-fold	10-fold	JJ
cord-023443-pvz7dll9	481	10	higher	high	JJR
cord-023443-pvz7dll9	481	11	in	in	IN
cord-023443-pvz7dll9	481	12	MBL	MBL	NNP
cord-023443-pvz7dll9	481	13	KO	KO	NNP
cord-023443-pvz7dll9	481	14	than	than	IN
cord-023443-pvz7dll9	481	15	in	in	IN
cord-023443-pvz7dll9	481	16	WT	WT	NNP
cord-023443-pvz7dll9	481	17	control	control	NN
cord-023443-pvz7dll9	481	18	animals	animal	NNS
cord-023443-pvz7dll9	481	19	.	.	.
cord-023443-pvz7dll9	482	1	Similar	similar	JJ
cord-023443-pvz7dll9	482	2	to	to	IN
cord-023443-pvz7dll9	482	3	the	the	DT
cord-023443-pvz7dll9	482	4	response	response	NN
cord-023443-pvz7dll9	482	5	to	to	TO
cord-023443-pvz7dll9	482	6	HbsAg	HbsAg	NNP
cord-023443-pvz7dll9	482	7	,	,	,
cord-023443-pvz7dll9	482	8	other	other	JJ
cord-023443-pvz7dll9	482	9	glycosylated	glycosylated	JJ
cord-023443-pvz7dll9	482	10	soluble	soluble	JJ
cord-023443-pvz7dll9	482	11	antigens	antigen	NNS
cord-023443-pvz7dll9	482	12	(	(	-LRB-
cord-023443-pvz7dll9	482	13	e.g.	e.g.	IN
cord-023443-pvz7dll9	482	14	invertase	invertase	NNP
cord-023443-pvz7dll9	482	15	)	)	-RRB-
cord-023443-pvz7dll9	482	16	induced	induce	VBN
cord-023443-pvz7dll9	482	17	better	well	JJR
cord-023443-pvz7dll9	482	18	humoural	humoural	JJ
cord-023443-pvz7dll9	482	19	responses	response	NNS
cord-023443-pvz7dll9	482	20	in	in	IN
cord-023443-pvz7dll9	482	21	MBL	MBL	NNP
cord-023443-pvz7dll9	482	22	double	double	JJ
cord-023443-pvz7dll9	482	23	KO	KO	NNP
cord-023443-pvz7dll9	482	24	animals	animal	NNS
cord-023443-pvz7dll9	482	25	,	,	,
cord-023443-pvz7dll9	482	26	suggesting	suggest	VBG
cord-023443-pvz7dll9	482	27	that	that	IN
cord-023443-pvz7dll9	482	28	MBL	MBL	NNP
cord-023443-pvz7dll9	482	29	plays	play	VBZ
cord-023443-pvz7dll9	482	30	an	an	DT
cord-023443-pvz7dll9	482	31	important	important	JJ
cord-023443-pvz7dll9	482	32	role	role	NN
cord-023443-pvz7dll9	482	33	in	in	IN
cord-023443-pvz7dll9	482	34	a	a	DT
cord-023443-pvz7dll9	482	35	negative	negative	JJ
cord-023443-pvz7dll9	482	36	feedback	feedback	NN
cord-023443-pvz7dll9	482	37	regulation	regulation	NN
cord-023443-pvz7dll9	482	38	of	of	IN
cord-023443-pvz7dll9	482	39	adaptive	adaptive	JJ
cord-023443-pvz7dll9	482	40	immunity	immunity	NN
cord-023443-pvz7dll9	482	41	.	.	.
cord-023443-pvz7dll9	483	1	Reconstitution	reconstitution	NN
cord-023443-pvz7dll9	483	2	experiments	experiment	NNS
cord-023443-pvz7dll9	483	3	with	with	IN
cord-023443-pvz7dll9	483	4	rMBL	rMBL	NNS
cord-023443-pvz7dll9	483	5	partially	partially	RB
cord-023443-pvz7dll9	483	6	rescued	rescue	VBD
cord-023443-pvz7dll9	483	7	the	the	DT
cord-023443-pvz7dll9	483	8	KO	KO	NNP
cord-023443-pvz7dll9	483	9	phenotype	phenotype	NN
cord-023443-pvz7dll9	483	10	.	.	.
cord-023443-pvz7dll9	484	1	We	-PRON-	PRP
cord-023443-pvz7dll9	484	2	propose	propose	VBP
cord-023443-pvz7dll9	484	3	that	that	IN
cord-023443-pvz7dll9	484	4	the	the	DT
cord-023443-pvz7dll9	484	5	clearance	clearance	NN
cord-023443-pvz7dll9	484	6	of	of	IN
cord-023443-pvz7dll9	484	7	glycoprotein	glycoprotein	NN
cord-023443-pvz7dll9	484	8	antigens	antigen	NNS
cord-023443-pvz7dll9	484	9	in	in	IN
cord-023443-pvz7dll9	484	10	MBL	MBL	NNP
cord-023443-pvz7dll9	484	11	KO	KO	NNP
cord-023443-pvz7dll9	484	12	is	be	VBZ
cord-023443-pvz7dll9	484	13	handled	handle	VBN
cord-023443-pvz7dll9	484	14	differently	differently	RB
cord-023443-pvz7dll9	484	15	from	from	IN
cord-023443-pvz7dll9	484	16	the	the	DT
cord-023443-pvz7dll9	484	17	WT	WT	NNP
cord-023443-pvz7dll9	484	18	,	,	,
cord-023443-pvz7dll9	484	19	resulting	result	VBG
cord-023443-pvz7dll9	484	20	in	in	IN
cord-023443-pvz7dll9	484	21	better	well	JJR
cord-023443-pvz7dll9	484	22	stimulation	stimulation	NN
cord-023443-pvz7dll9	484	23	of	of	IN
cord-023443-pvz7dll9	484	24	humoural	humoural	JJ
cord-023443-pvz7dll9	484	25	responses	response	NNS
cord-023443-pvz7dll9	484	26	.	.	.
cord-023443-pvz7dll9	485	1	Alternatively	alternatively	RB
cord-023443-pvz7dll9	485	2	,	,	,
cord-023443-pvz7dll9	485	3	glycoprotein	glycoprotein	NN
cord-023443-pvz7dll9	485	4	-	-	:
cord-023443-pvz7dll9	485	5	Ag	Ag	NNP
cord-023443-pvz7dll9	485	6	-	-	HYPH
cord-023443-pvz7dll9	485	7	MBL	MBL	NNP
cord-023443-pvz7dll9	485	8	-	-	HYPH
cord-023443-pvz7dll9	485	9	rich	rich	JJ
cord-023443-pvz7dll9	485	10	complexes	complex	NNS
cord-023443-pvz7dll9	485	11	inhibit	inhibit	VBP
cord-023443-pvz7dll9	485	12	B	b	NN
cord-023443-pvz7dll9	485	13	-	-	HYPH
cord-023443-pvz7dll9	485	14	cell	cell	NN
cord-023443-pvz7dll9	485	15	responsiveness	responsiveness	NN
cord-023443-pvz7dll9	485	16	via	via	IN
cord-023443-pvz7dll9	485	17	putative	putative	JJ
cord-023443-pvz7dll9	485	18	MBL	MBL	NNP
cord-023443-pvz7dll9	485	19	receptors	receptor	NNS
cord-023443-pvz7dll9	485	20	.	.	.
cord-023443-pvz7dll9	486	1	The	the	DT
cord-023443-pvz7dll9	486	2	complement	complement	NN
cord-023443-pvz7dll9	486	3	system	system	NN
cord-023443-pvz7dll9	486	4	is	be	VBZ
cord-023443-pvz7dll9	486	5	an	an	DT
cord-023443-pvz7dll9	486	6	important	important	JJ
cord-023443-pvz7dll9	486	7	part	part	NN
cord-023443-pvz7dll9	486	8	of	of	IN
cord-023443-pvz7dll9	486	9	the	the	DT
cord-023443-pvz7dll9	486	10	innate	innate	JJ
cord-023443-pvz7dll9	486	11	immune	immune	JJ
cord-023443-pvz7dll9	486	12	system	system	NN
cord-023443-pvz7dll9	486	13	.	.	.
cord-023443-pvz7dll9	487	1	The	the	DT
cord-023443-pvz7dll9	487	2	activation	activation	NN
cord-023443-pvz7dll9	487	3	of	of	IN
cord-023443-pvz7dll9	487	4	complement	complement	NN
cord-023443-pvz7dll9	487	5	proceeds	proceed	VBZ
cord-023443-pvz7dll9	487	6	through	through	IN
cord-023443-pvz7dll9	487	7	three	three	CD
cord-023443-pvz7dll9	487	8	different	different	JJ
cord-023443-pvz7dll9	487	9	pathways	pathway	NNS
cord-023443-pvz7dll9	487	10	that	that	WDT
cord-023443-pvz7dll9	487	11	converge	converge	VBP
cord-023443-pvz7dll9	487	12	in	in	IN
cord-023443-pvz7dll9	487	13	the	the	DT
cord-023443-pvz7dll9	487	14	generation	generation	NN
cord-023443-pvz7dll9	487	15	of	of	IN
cord-023443-pvz7dll9	487	16	C3-activating	c3-activate	VBG
cord-023443-pvz7dll9	487	17	enzyme	enzyme	NN
cord-023443-pvz7dll9	487	18	complexes	complex	NNS
cord-023443-pvz7dll9	487	19	.	.	.
cord-023443-pvz7dll9	488	1	Complement	complement	JJ
cord-023443-pvz7dll9	488	2	activation	activation	NN
cord-023443-pvz7dll9	488	3	via	via	IN
cord-023443-pvz7dll9	488	4	the	the	DT
cord-023443-pvz7dll9	488	5	lectin	lectin	NN
cord-023443-pvz7dll9	488	6	pathway	pathway	NN
cord-023443-pvz7dll9	488	7	is	be	VBZ
cord-023443-pvz7dll9	488	8	initiated	initiate	VBN
cord-023443-pvz7dll9	488	9	when	when	WRB
cord-023443-pvz7dll9	488	10	recognition	recognition	NN
cord-023443-pvz7dll9	488	11	molecules	molecule	NNS
cord-023443-pvz7dll9	488	12	,	,	,
cord-023443-pvz7dll9	488	13	mannan	mannan	NN
cord-023443-pvz7dll9	488	14	-	-	HYPH
cord-023443-pvz7dll9	488	15	binding	bind	VBG
cord-023443-pvz7dll9	488	16	lectin	lectin	NN
cord-023443-pvz7dll9	488	17	(	(	-LRB-
cord-023443-pvz7dll9	488	18	MBL	MBL	NNP
cord-023443-pvz7dll9	488	19	)	)	-RRB-
cord-023443-pvz7dll9	488	20	or	or	CC
cord-023443-pvz7dll9	488	21	ficolin	ficolin	NN
cord-023443-pvz7dll9	488	22	,	,	,
cord-023443-pvz7dll9	488	23	bind	bind	VB
cord-023443-pvz7dll9	488	24	to	to	IN
cord-023443-pvz7dll9	488	25	carbohydrate	carbohydrate	NN
cord-023443-pvz7dll9	488	26	structures	structure	NNS
cord-023443-pvz7dll9	488	27	characteristic	characteristic	JJ
cord-023443-pvz7dll9	488	28	for	for	IN
cord-023443-pvz7dll9	488	29	microbial	microbial	JJ
cord-023443-pvz7dll9	488	30	surfaces	surface	NNS
cord-023443-pvz7dll9	488	31	.	.	.
cord-023443-pvz7dll9	489	1	In	in	IN
cord-023443-pvz7dll9	489	2	the	the	DT
cord-023443-pvz7dll9	489	3	circulation	circulation	NN
cord-023443-pvz7dll9	489	4	,	,	,
cord-023443-pvz7dll9	489	5	MBL	MBL	NNP
cord-023443-pvz7dll9	489	6	and	and	CC
cord-023443-pvz7dll9	489	7	ficolins	ficolin	NNS
cord-023443-pvz7dll9	489	8	are	be	VBP
cord-023443-pvz7dll9	489	9	found	find	VBN
cord-023443-pvz7dll9	489	10	in	in	IN
cord-023443-pvz7dll9	489	11	association	association	NN
cord-023443-pvz7dll9	489	12	with	with	IN
cord-023443-pvz7dll9	489	13	three	three	CD
cord-023443-pvz7dll9	489	14	structurally	structurally	RB
cord-023443-pvz7dll9	489	15	related	relate	VBN
cord-023443-pvz7dll9	489	16	MBLassociated	mblassociated	JJ
cord-023443-pvz7dll9	489	17	serine	serine	NN
cord-023443-pvz7dll9	489	18	proteases	protease	NNS
cord-023443-pvz7dll9	489	19	(	(	-LRB-
cord-023443-pvz7dll9	489	20	MASP)-1	masp)-1	NN
cord-023443-pvz7dll9	489	21	,	,	,
cord-023443-pvz7dll9	489	22	-2	-2	NNP
cord-023443-pvz7dll9	489	23	and	and	CC
cord-023443-pvz7dll9	489	24	-3	-3	NNP
cord-023443-pvz7dll9	489	25	and	and	CC
cord-023443-pvz7dll9	489	26	a	a	DT
cord-023443-pvz7dll9	489	27	small	small	JJ
cord-023443-pvz7dll9	489	28	,	,	,
cord-023443-pvz7dll9	489	29	nonenzymatic	nonenzymatic	JJ
cord-023443-pvz7dll9	489	30	component	component	NN
cord-023443-pvz7dll9	489	31	,	,	,
cord-023443-pvz7dll9	489	32	MAp19	MAp19	NNP
cord-023443-pvz7dll9	489	33	.	.	.
cord-023443-pvz7dll9	490	1	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	490	2	has	have	VBZ
cord-023443-pvz7dll9	490	3	been	be	VBN
cord-023443-pvz7dll9	490	4	shown	show	VBN
cord-023443-pvz7dll9	490	5	to	to	TO
cord-023443-pvz7dll9	490	6	elicit	elicit	VB
cord-023443-pvz7dll9	490	7	complement	complement	NN
cord-023443-pvz7dll9	490	8	activation	activation	NN
cord-023443-pvz7dll9	490	9	through	through	IN
cord-023443-pvz7dll9	490	10	the	the	DT
cord-023443-pvz7dll9	490	11	sequential	sequential	JJ
cord-023443-pvz7dll9	490	12	proteolytic	proteolytic	JJ
cord-023443-pvz7dll9	490	13	cleavage	cleavage	NN
cord-023443-pvz7dll9	490	14	of	of	IN
cord-023443-pvz7dll9	490	15	C4	c4	NN
cord-023443-pvz7dll9	490	16	and	and	CC
cord-023443-pvz7dll9	490	17	C2	C2	NNP
cord-023443-pvz7dll9	490	18	upon	upon	IN
cord-023443-pvz7dll9	490	19	binding	bind	VBG
cord-023443-pvz7dll9	490	20	of	of	IN
cord-023443-pvz7dll9	490	21	MBL	MBL	NNP
cord-023443-pvz7dll9	490	22	/	/	SYM
cord-023443-pvz7dll9	490	23	MASP-2	masp-2	NN
cord-023443-pvz7dll9	490	24	complexes	complex	NNS
cord-023443-pvz7dll9	490	25	to	to	IN
cord-023443-pvz7dll9	490	26	microbial	microbial	JJ
cord-023443-pvz7dll9	490	27	surfaces	surface	NNS
cord-023443-pvz7dll9	490	28	.	.	.
cord-023443-pvz7dll9	491	1	We	-PRON-	PRP
cord-023443-pvz7dll9	491	2	have	have	VBP
cord-023443-pvz7dll9	491	3	recently	recently	RB
cord-023443-pvz7dll9	491	4	uncovered	uncover	VBN
cord-023443-pvz7dll9	491	5	a	a	DT
cord-023443-pvz7dll9	491	6	polymorphism	polymorphism	NN
cord-023443-pvz7dll9	491	7	in	in	IN
cord-023443-pvz7dll9	491	8	the	the	DT
cord-023443-pvz7dll9	491	9	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	491	10	/	/	SYM
cord-023443-pvz7dll9	491	11	MAp19	map19	NN
cord-023443-pvz7dll9	491	12	gene	gene	NN
cord-023443-pvz7dll9	491	13	in	in	IN
cord-023443-pvz7dll9	491	14	a	a	DT
cord-023443-pvz7dll9	491	15	patient	patient	NN
cord-023443-pvz7dll9	491	16	shown	show	VBN
cord-023443-pvz7dll9	491	17	to	to	TO
cord-023443-pvz7dll9	491	18	be	be	VB
cord-023443-pvz7dll9	491	19	deficient	deficient	JJ
cord-023443-pvz7dll9	491	20	in	in	IN
cord-023443-pvz7dll9	491	21	the	the	DT
cord-023443-pvz7dll9	491	22	lectin	lectin	NN
cord-023443-pvz7dll9	491	23	pathway	pathway	NN
cord-023443-pvz7dll9	491	24	of	of	IN
cord-023443-pvz7dll9	491	25	complement	complement	JJ
cord-023443-pvz7dll9	491	26	activation	activation	NN
cord-023443-pvz7dll9	491	27	.	.	.
cord-023443-pvz7dll9	492	1	The	the	DT
cord-023443-pvz7dll9	492	2	polymorphism	polymorphism	NN
cord-023443-pvz7dll9	492	3	results	result	VBZ
cord-023443-pvz7dll9	492	4	in	in	IN
cord-023443-pvz7dll9	492	5	a	a	DT
cord-023443-pvz7dll9	492	6	single	single	JJ
cord-023443-pvz7dll9	492	7	amino	amino	NN
cord-023443-pvz7dll9	492	8	acid	acid	NN
cord-023443-pvz7dll9	492	9	substitution	substitution	NN
cord-023443-pvz7dll9	492	10	in	in	IN
cord-023443-pvz7dll9	492	11	the	the	DT
cord-023443-pvz7dll9	492	12	N	n	CD
cord-023443-pvz7dll9	492	13	-	-	HYPH
cord-023443-pvz7dll9	492	14	terminal	terminal	JJ
cord-023443-pvz7dll9	492	15	part	part	NN
cord-023443-pvz7dll9	492	16	of	of	IN
cord-023443-pvz7dll9	492	17	the	the	DT
cord-023443-pvz7dll9	492	18	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	492	19	protein	protein	NN
cord-023443-pvz7dll9	492	20	.	.	.
cord-023443-pvz7dll9	493	1	Recombinant	recombinant	JJ
cord-023443-pvz7dll9	493	2	wildtype	wildtype	NN
cord-023443-pvz7dll9	493	3	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	493	4	and	and	CC
cord-023443-pvz7dll9	493	5	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	493	6	containing	contain	VBG
cord-023443-pvz7dll9	493	7	the	the	DT
cord-023443-pvz7dll9	493	8	amino	amino	NN
cord-023443-pvz7dll9	493	9	acid	acid	NN
cord-023443-pvz7dll9	493	10	substitution	substitution	NN
cord-023443-pvz7dll9	493	11	in	in	IN
cord-023443-pvz7dll9	493	12	question	question	NN
cord-023443-pvz7dll9	493	13	was	be	VBD
cord-023443-pvz7dll9	493	14	produced	produce	VBN
cord-023443-pvz7dll9	493	15	,	,	,
cord-023443-pvz7dll9	493	16	and	and	CC
cord-023443-pvz7dll9	493	17	the	the	DT
cord-023443-pvz7dll9	493	18	ability	ability	NN
cord-023443-pvz7dll9	493	19	to	to	TO
cord-023443-pvz7dll9	493	20	activate	activate	VB
cord-023443-pvz7dll9	493	21	complement	complement	NN
cord-023443-pvz7dll9	493	22	was	be	VBD
cord-023443-pvz7dll9	493	23	studied	study	VBN
cord-023443-pvz7dll9	493	24	.	.	.
cord-023443-pvz7dll9	494	1	The	the	DT
cord-023443-pvz7dll9	494	2	mutation	mutation	NN
cord-023443-pvz7dll9	494	3	had	have	VBD
cord-023443-pvz7dll9	494	4	a	a	DT
cord-023443-pvz7dll9	494	5	profound	profound	JJ
cord-023443-pvz7dll9	494	6	impact	impact	NN
cord-023443-pvz7dll9	494	7	on	on	IN
cord-023443-pvz7dll9	494	8	MASP-2	masp-2	NN
cord-023443-pvz7dll9	494	9	function	function	NN
cord-023443-pvz7dll9	494	10	,	,	,
cord-023443-pvz7dll9	494	11	resulting	result	VBG
cord-023443-pvz7dll9	494	12	in	in	IN
cord-023443-pvz7dll9	494	13	the	the	DT
cord-023443-pvz7dll9	494	14	lack	lack	NN
cord-023443-pvz7dll9	494	15	of	of	IN
cord-023443-pvz7dll9	494	16	complement	complement	JJ
cord-023443-pvz7dll9	494	17	activation	activation	NN
cord-023443-pvz7dll9	494	18	through	through	IN
cord-023443-pvz7dll9	494	19	the	the	DT
cord-023443-pvz7dll9	494	20	lectin	lectin	NN
cord-023443-pvz7dll9	494	21	pathway	pathway	NN
cord-023443-pvz7dll9	494	22	.	.	.
cord-023443-pvz7dll9	495	1	ELISA	ELISA	NNP
cord-023443-pvz7dll9	495	2	-	-	HYPH
cord-023443-pvz7dll9	495	3	based	base	VBN
cord-023443-pvz7dll9	495	4	experiments	experiment	NNS
cord-023443-pvz7dll9	495	5	showed	show	VBD
cord-023443-pvz7dll9	495	6	that	that	IN
cord-023443-pvz7dll9	495	7	the	the	DT
cord-023443-pvz7dll9	495	8	mutation	mutation	NN
cord-023443-pvz7dll9	495	9	leads	lead	VBZ
cord-023443-pvz7dll9	495	10	to	to	IN
cord-023443-pvz7dll9	495	11	the	the	DT
cord-023443-pvz7dll9	495	12	impairment	impairment	NN
cord-023443-pvz7dll9	495	13	of	of	IN
cord-023443-pvz7dll9	495	14	complement	complement	JJ
cord-023443-pvz7dll9	495	15	activation	activation	NN
cord-023443-pvz7dll9	495	16	through	through	IN
cord-023443-pvz7dll9	495	17	influencing	influence	VBG
cord-023443-pvz7dll9	495	18	the	the	DT
cord-023443-pvz7dll9	495	19	binding	binding	NN
cord-023443-pvz7dll9	495	20	of	of	IN
cord-023443-pvz7dll9	495	21	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	495	22	to	to	IN
cord-023443-pvz7dll9	495	23	MBL	MBL	NNP
cord-023443-pvz7dll9	495	24	or	or	CC
cord-023443-pvz7dll9	495	25	ficolins	ficolin	NNS
cord-023443-pvz7dll9	495	26	.	.	.
cord-023443-pvz7dll9	496	1	Deficiencies	deficiency	NNS
cord-023443-pvz7dll9	496	2	in	in	IN
cord-023443-pvz7dll9	496	3	the	the	DT
cord-023443-pvz7dll9	496	4	lectin	lectin	NN
cord-023443-pvz7dll9	496	5	pathway	pathway	NN
cord-023443-pvz7dll9	496	6	of	of	IN
cord-023443-pvz7dll9	496	7	complement	complement	JJ
cord-023443-pvz7dll9	496	8	activation	activation	NN
cord-023443-pvz7dll9	496	9	have	have	VBP
cord-023443-pvz7dll9	496	10	so	so	RB
cord-023443-pvz7dll9	496	11	far	far	RB
cord-023443-pvz7dll9	496	12	been	be	VBN
cord-023443-pvz7dll9	496	13	accounted	account	VBN
cord-023443-pvz7dll9	496	14	for	for	IN
cord-023443-pvz7dll9	496	15	only	only	RB
cord-023443-pvz7dll9	496	16	by	by	IN
cord-023443-pvz7dll9	496	17	lack	lack	NN
cord-023443-pvz7dll9	496	18	of	of	IN
cord-023443-pvz7dll9	496	19	functional	functional	JJ
cord-023443-pvz7dll9	496	20	MBL	MBL	NNS
cord-023443-pvz7dll9	496	21	.	.	.
cord-023443-pvz7dll9	497	1	The	the	DT
cord-023443-pvz7dll9	497	2	mutation	mutation	NN
cord-023443-pvz7dll9	497	3	described	describe	VBN
cord-023443-pvz7dll9	497	4	above	above	RB
cord-023443-pvz7dll9	497	5	is	be	VBZ
cord-023443-pvz7dll9	497	6	the	the	DT
cord-023443-pvz7dll9	497	7	first	first	JJ
cord-023443-pvz7dll9	497	8	defect	defect	NN
cord-023443-pvz7dll9	497	9	described	describe	VBN
cord-023443-pvz7dll9	497	10	affecting	affect	VBG
cord-023443-pvz7dll9	497	11	both	both	DT
cord-023443-pvz7dll9	497	12	activation	activation	NN
cord-023443-pvz7dll9	497	13	through	through	IN
cord-023443-pvz7dll9	497	14	MBL	MBL	NNP
cord-023443-pvz7dll9	497	15	and	and	CC
cord-023443-pvz7dll9	497	16	the	the	DT
cord-023443-pvz7dll9	497	17	ficolins	ficolin	NNS
cord-023443-pvz7dll9	497	18	.	.	.
cord-023443-pvz7dll9	497	19	..................................................................................................................................................................................................	..................................................................................................................................................................................................	.
cord-023443-pvz7dll9	498	1	Th1	Th1	NNP
cord-023443-pvz7dll9	498	2	,	,	,
cord-023443-pvz7dll9	498	3	Th2	Th2	NNP
cord-023443-pvz7dll9	498	4	and	and	CC
cord-023443-pvz7dll9	498	5	Treg	Treg	NNP
cord-023443-pvz7dll9	498	6	cell	cell	NN
cord-023443-pvz7dll9	498	7	balance	balance	NN
cord-023443-pvz7dll9	498	8	.	.	.
cord-023443-pvz7dll9	499	1	DCs	DCs	NNP
cord-023443-pvz7dll9	499	2	are	be	VBP
cord-023443-pvz7dll9	499	3	present	present	JJ
cord-023443-pvz7dll9	499	4	in	in	IN
cord-023443-pvz7dll9	499	5	the	the	DT
cord-023443-pvz7dll9	499	6	gut	gut	NN
cord-023443-pvz7dll9	499	7	mucosa	mucosa	NN
cord-023443-pvz7dll9	499	8	and	and	CC
cord-023443-pvz7dll9	499	9	may	may	MD
cord-023443-pvz7dll9	499	10	thus	thus	RB
cord-023443-pvz7dll9	499	11	be	be	VB
cord-023443-pvz7dll9	499	12	target	target	NN
cord-023443-pvz7dll9	499	13	for	for	IN
cord-023443-pvz7dll9	499	14	modulation	modulation	NN
cord-023443-pvz7dll9	499	15	by	by	IN
cord-023443-pvz7dll9	499	16	gut	gut	NN
cord-023443-pvz7dll9	499	17	microbes	microbe	NNS
cord-023443-pvz7dll9	499	18	,	,	,
cord-023443-pvz7dll9	499	19	including	include	VBG
cord-023443-pvz7dll9	499	20	ingested	ingest	VBN
cord-023443-pvz7dll9	499	21	probiotics	probiotic	NNS
cord-023443-pvz7dll9	499	22	.	.	.
cord-023443-pvz7dll9	500	1	Here	here	RB
cord-023443-pvz7dll9	500	2	,	,	,
cord-023443-pvz7dll9	500	3	we	-PRON-	PRP
cord-023443-pvz7dll9	500	4	tested	test	VBD
cord-023443-pvz7dll9	500	5	the	the	DT
cord-023443-pvz7dll9	500	6	hypothesis	hypothesis	NN
cord-023443-pvz7dll9	500	7	that	that	WDT
cord-023443-pvz7dll9	500	8	species	specie	NNS
cord-023443-pvz7dll9	500	9	of	of	IN
cord-023443-pvz7dll9	500	10	lactic	lactic	JJ
cord-023443-pvz7dll9	500	11	acid	acid	NN
cord-023443-pvz7dll9	500	12	bacteria	bacteria	NNS
cord-023443-pvz7dll9	500	13	,	,	,
cord-023443-pvz7dll9	500	14	important	important	JJ
cord-023443-pvz7dll9	500	15	members	member	NNS
cord-023443-pvz7dll9	500	16	of	of	IN
cord-023443-pvz7dll9	500	17	the	the	DT
cord-023443-pvz7dll9	500	18	gut	gut	NN
cord-023443-pvz7dll9	500	19	flora	flora	NNS
cord-023443-pvz7dll9	500	20	,	,	,
cord-023443-pvz7dll9	500	21	differentially	differentially	RB
cord-023443-pvz7dll9	500	22	activate	activate	VB
cord-023443-pvz7dll9	500	23	DC	DC	NNP
cord-023443-pvz7dll9	500	24	.	.	.
cord-023443-pvz7dll9	501	1	A	a	DT
cord-023443-pvz7dll9	501	2	large	large	JJ
cord-023443-pvz7dll9	501	3	panel	panel	NN
cord-023443-pvz7dll9	501	4	of	of	IN
cord-023443-pvz7dll9	501	5	human	human	JJ
cord-023443-pvz7dll9	501	6	gut	gut	NN
cord-023443-pvz7dll9	501	7	-	-	HYPH
cord-023443-pvz7dll9	501	8	derived	derive	VBN
cord-023443-pvz7dll9	501	9	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	501	10	and	and	CC
cord-023443-pvz7dll9	501	11	Bifidobacterium	bifidobacterium	NN
cord-023443-pvz7dll9	501	12	spp	spp	NNS
cord-023443-pvz7dll9	501	13	.	.	.
cord-023443-pvz7dll9	502	1	was	be	VBD
cord-023443-pvz7dll9	502	2	screened	screen	VBN
cord-023443-pvz7dll9	502	3	for	for	IN
cord-023443-pvz7dll9	502	4	DC	DC	NNP
cord-023443-pvz7dll9	502	5	-	-	HYPH
cord-023443-pvz7dll9	502	6	polarizing	polarize	VBG
cord-023443-pvz7dll9	502	7	capacity	capacity	NN
cord-023443-pvz7dll9	502	8	by	by	IN
cord-023443-pvz7dll9	502	9	exposing	expose	VBG
cord-023443-pvz7dll9	502	10	bone	bone	NN
cord-023443-pvz7dll9	502	11	marrow	marrow	NN
cord-023443-pvz7dll9	502	12	-	-	HYPH
cord-023443-pvz7dll9	502	13	derived	derive	VBN
cord-023443-pvz7dll9	502	14	murine	murine	JJ
cord-023443-pvz7dll9	502	15	DC	DC	NNP
cord-023443-pvz7dll9	502	16	to	to	IN
cord-023443-pvz7dll9	502	17	lethally	lethally	RB
cord-023443-pvz7dll9	502	18	irradiated	irradiate	VBN
cord-023443-pvz7dll9	502	19	bacteria	bacteria	NNS
cord-023443-pvz7dll9	502	20	.	.	.
cord-023443-pvz7dll9	503	1	Cytokines	cytokine	NNS
cord-023443-pvz7dll9	503	2	in	in	IN
cord-023443-pvz7dll9	503	3	culture	culture	NN
cord-023443-pvz7dll9	503	4	supernatants	supernatant	NNS
cord-023443-pvz7dll9	503	5	and	and	CC
cord-023443-pvz7dll9	503	6	DC	DC	NNP
cord-023443-pvz7dll9	503	7	-	-	HYPH
cord-023443-pvz7dll9	503	8	surface	surface	NN
cord-023443-pvz7dll9	503	9	maturation	maturation	NN
cord-023443-pvz7dll9	503	10	markers	marker	NNS
cord-023443-pvz7dll9	503	11	were	be	VBD
cord-023443-pvz7dll9	503	12	analysed	analyse	VBN
cord-023443-pvz7dll9	503	13	.	.	.
cord-023443-pvz7dll9	504	1	Substantial	substantial	JJ
cord-023443-pvz7dll9	504	2	differences	difference	NNS
cord-023443-pvz7dll9	504	3	were	be	VBD
cord-023443-pvz7dll9	504	4	found	find	VBN
cord-023443-pvz7dll9	504	5	among	among	IN
cord-023443-pvz7dll9	504	6	strains	strain	NNS
cord-023443-pvz7dll9	504	7	in	in	IN
cord-023443-pvz7dll9	504	8	the	the	DT
cord-023443-pvz7dll9	504	9	capacity	capacity	NN
cord-023443-pvz7dll9	504	10	to	to	TO
cord-023443-pvz7dll9	504	11	induce	induce	VB
cord-023443-pvz7dll9	504	12	interleukin-12	interleukin-12	XX
cord-023443-pvz7dll9	504	13	(	(	-LRB-
cord-023443-pvz7dll9	504	14	IL-12	IL-12	NNP
cord-023443-pvz7dll9	504	15	)	)	-RRB-
cord-023443-pvz7dll9	504	16	and	and	CC
cord-023443-pvz7dll9	504	17	tumour	tumour	NN
cord-023443-pvz7dll9	504	18	necrosis	necrosis	NN
cord-023443-pvz7dll9	504	19	factor	factor	NN
cord-023443-pvz7dll9	504	20	(	(	-LRB-
cord-023443-pvz7dll9	505	1	TNF)-a	TNF)-a	NNP
cord-023443-pvz7dll9	505	2	,	,	,
cord-023443-pvz7dll9	505	3	while	while	IN
cord-023443-pvz7dll9	505	4	the	the	DT
cord-023443-pvz7dll9	505	5	differences	difference	NNS
cord-023443-pvz7dll9	505	6	for	for	IN
cord-023443-pvz7dll9	505	7	IL-10	IL-10	NNP
cord-023443-pvz7dll9	505	8	and	and	CC
cord-023443-pvz7dll9	505	9	IL-6	IL-6	NNP
cord-023443-pvz7dll9	505	10	were	be	VBD
cord-023443-pvz7dll9	505	11	less	less	RBR
cord-023443-pvz7dll9	505	12	pronounced	pronounced	JJ
cord-023443-pvz7dll9	505	13	.	.	.
cord-023443-pvz7dll9	506	1	Bifidobacteria	Bifidobacteria	NNP
cord-023443-pvz7dll9	506	2	tended	tend	VBD
cord-023443-pvz7dll9	506	3	to	to	TO
cord-023443-pvz7dll9	506	4	be	be	VB
cord-023443-pvz7dll9	506	5	weak	weak	JJ
cord-023443-pvz7dll9	506	6	IL-12	IL-12	NNP
cord-023443-pvz7dll9	506	7	and	and	CC
cord-023443-pvz7dll9	506	8	TNF	TNF	NNP
cord-023443-pvz7dll9	506	9	-	-	,
cord-023443-pvz7dll9	506	10	a	a	DT
cord-023443-pvz7dll9	506	11	inducers	inducer	NNS
cord-023443-pvz7dll9	506	12	,	,	,
cord-023443-pvz7dll9	506	13	while	while	IN
cord-023443-pvz7dll9	506	14	both	both	CC
cord-023443-pvz7dll9	506	15	strong	strong	JJ
cord-023443-pvz7dll9	506	16	and	and	CC
cord-023443-pvz7dll9	506	17	weak	weak	JJ
cord-023443-pvz7dll9	506	18	IL-12	IL-12	NNP
cord-023443-pvz7dll9	506	19	inducers	inducer	NNS
cord-023443-pvz7dll9	506	20	were	be	VBD
cord-023443-pvz7dll9	506	21	found	find	VBN
cord-023443-pvz7dll9	506	22	among	among	IN
cord-023443-pvz7dll9	506	23	the	the	DT
cord-023443-pvz7dll9	506	24	strains	strain	NNS
cord-023443-pvz7dll9	506	25	of	of	IN
cord-023443-pvz7dll9	506	26	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	506	27	.	.	.
cord-023443-pvz7dll9	507	1	Remarkably	remarkably	RB
cord-023443-pvz7dll9	507	2	,	,	,
cord-023443-pvz7dll9	507	3	strains	strain	NNS
cord-023443-pvz7dll9	507	4	weak	weak	JJ
cord-023443-pvz7dll9	507	5	in	in	IN
cord-023443-pvz7dll9	507	6	IL-12	IL-12	NNP
cord-023443-pvz7dll9	507	7	induction	induction	NN
cord-023443-pvz7dll9	507	8	inhibited	inhibit	VBN
cord-023443-pvz7dll9	507	9	IL-12	IL-12	NNP
cord-023443-pvz7dll9	507	10	and	and	CC
cord-023443-pvz7dll9	507	11	TNF	TNF	NNP
cord-023443-pvz7dll9	507	12	-	-	:
cord-023443-pvz7dll9	507	13	a	a	DT
cord-023443-pvz7dll9	507	14	production	production	NN
cord-023443-pvz7dll9	507	15	induced	induce	VBN
cord-023443-pvz7dll9	507	16	by	by	IN
cord-023443-pvz7dll9	507	17	an	an	DT
cord-023443-pvz7dll9	507	18	otherwise	otherwise	RB
cord-023443-pvz7dll9	507	19	strong	strong	JJ
cord-023443-pvz7dll9	507	20	cytokine	cytokine	NN
cord-023443-pvz7dll9	507	21	-	-	HYPH
cord-023443-pvz7dll9	507	22	inducing	induce	VBG
cord-023443-pvz7dll9	507	23	strain	strain	NN
cord-023443-pvz7dll9	507	24	of	of	IN
cord-023443-pvz7dll9	507	25	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	507	26	casei	casei	NN
cord-023443-pvz7dll9	507	27	,	,	,
cord-023443-pvz7dll9	507	28	while	while	IN
cord-023443-pvz7dll9	507	29	IL-10	IL-10	NNP
cord-023443-pvz7dll9	507	30	production	production	NN
cord-023443-pvz7dll9	507	31	remained	remain	VBD
cord-023443-pvz7dll9	507	32	unaltered	unaltered	JJ
cord-023443-pvz7dll9	507	33	.	.	.
cord-023443-pvz7dll9	508	1	Selected	select	VBN
cord-023443-pvz7dll9	508	2	strains	strain	NNS
cord-023443-pvz7dll9	508	3	were	be	VBD
cord-023443-pvz7dll9	508	4	tested	test	VBN
cord-023443-pvz7dll9	508	5	for	for	IN
cord-023443-pvz7dll9	508	6	induction	induction	NN
cord-023443-pvz7dll9	508	7	of	of	IN
cord-023443-pvz7dll9	508	8	DC	DC	NNP
cord-023443-pvz7dll9	508	9	maturation	maturation	NN
cord-023443-pvz7dll9	508	10	markers	marker	NNS
cord-023443-pvz7dll9	508	11	.	.	.
cord-023443-pvz7dll9	509	1	Those	those	DT
cord-023443-pvz7dll9	509	2	lactobacilli	lactobacillus	NNS
cord-023443-pvz7dll9	509	3	with	with	IN
cord-023443-pvz7dll9	509	4	greatest	great	JJS
cord-023443-pvz7dll9	509	5	capacity	capacity	NN
cord-023443-pvz7dll9	509	6	to	to	TO
cord-023443-pvz7dll9	509	7	induce	induce	VB
cord-023443-pvz7dll9	509	8	IL-12	IL-12	NNP
cord-023443-pvz7dll9	509	9	were	be	VBD
cord-023443-pvz7dll9	509	10	most	most	RBS
cord-023443-pvz7dll9	509	11	effective	effective	JJ
cord-023443-pvz7dll9	509	12	in	in	IN
cord-023443-pvz7dll9	509	13	upregulating	upregulate	VBG
cord-023443-pvz7dll9	509	14	surface	surface	NN
cord-023443-pvz7dll9	509	15	MHC	MHC	NNP
cord-023443-pvz7dll9	509	16	class	class	NN
cord-023443-pvz7dll9	509	17	II	II	NNP
cord-023443-pvz7dll9	509	18	and	and	CC
cord-023443-pvz7dll9	509	19	CD86	CD86	NNP
cord-023443-pvz7dll9	509	20	.	.	.
cord-023443-pvz7dll9	510	1	Moreover	moreover	RB
cord-023443-pvz7dll9	510	2	,	,	,
cord-023443-pvz7dll9	510	3	L.	L.	NNP
cord-023443-pvz7dll9	510	4	casei	casei	NN
cord-023443-pvz7dll9	510	5	-	-	HYPH
cord-023443-pvz7dll9	510	6	induced	induce	VBN
cord-023443-pvz7dll9	510	7	upregulation	upregulation	NN
cord-023443-pvz7dll9	510	8	of	of	IN
cord-023443-pvz7dll9	510	9	CD86	CD86	NNP
cord-023443-pvz7dll9	510	10	was	be	VBD
cord-023443-pvz7dll9	510	11	reduced	reduce	VBN
cord-023443-pvz7dll9	510	12	in	in	IN
cord-023443-pvz7dll9	510	13	the	the	DT
cord-023443-pvz7dll9	510	14	presence	presence	NN
cord-023443-pvz7dll9	510	15	of	of	IN
cord-023443-pvz7dll9	510	16	a	a	DT
cord-023443-pvz7dll9	510	17	weak	weak	JJ
cord-023443-pvz7dll9	510	18	IL-12inducing	IL-12inducing	NNP
cord-023443-pvz7dll9	510	19	L.	L.	NNP
cord-023443-pvz7dll9	510	20	reuteri	reuteri	NN
cord-023443-pvz7dll9	510	21	.	.	.
cord-023443-pvz7dll9	511	1	In	in	IN
cord-023443-pvz7dll9	511	2	conclusion	conclusion	NN
cord-023443-pvz7dll9	511	3	,	,	,
cord-023443-pvz7dll9	511	4	human	human	JJ
cord-023443-pvz7dll9	511	5	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	511	6	and	and	CC
cord-023443-pvz7dll9	511	7	Bifidobacterium	bifidobacterium	NN
cord-023443-pvz7dll9	511	8	spp	spp	NNS
cord-023443-pvz7dll9	511	9	.	.	.
cord-023443-pvz7dll9	511	10	polarize	polarize	VB
cord-023443-pvz7dll9	511	11	differentially	differentially	RB
cord-023443-pvz7dll9	511	12	DC	DC	NNP
cord-023443-pvz7dll9	511	13	maturation	maturation	NN
cord-023443-pvz7dll9	511	14	.	.	.
cord-023443-pvz7dll9	512	1	Thus	thus	RB
cord-023443-pvz7dll9	512	2	,	,	,
cord-023443-pvz7dll9	512	3	the	the	DT
cord-023443-pvz7dll9	512	4	potential	potential	NN
cord-023443-pvz7dll9	512	5	exists	exist	VBZ
cord-023443-pvz7dll9	512	6	for	for	IN
cord-023443-pvz7dll9	512	7	Th1	th1	NN
cord-023443-pvz7dll9	512	8	/	/	SYM
cord-023443-pvz7dll9	512	9	Th2	Th2	NNP
cord-023443-pvz7dll9	512	10	/	/	SYM
cord-023443-pvz7dll9	512	11	Treg	Treg	NNP
cord-023443-pvz7dll9	512	12	-	-	HYPH
cord-023443-pvz7dll9	512	13	driving	drive	VBG
cord-023443-pvz7dll9	512	14	capacities	capacity	NNS
cord-023443-pvz7dll9	512	15	of	of	IN
cord-023443-pvz7dll9	512	16	the	the	DT
cord-023443-pvz7dll9	512	17	gut	gut	NN
cord-023443-pvz7dll9	512	18	DC	DC	NNP
cord-023443-pvz7dll9	512	19	to	to	TO
cord-023443-pvz7dll9	512	20	be	be	VB
cord-023443-pvz7dll9	512	21	modulated	modulate	VBN
cord-023443-pvz7dll9	512	22	according	accord	VBG
cord-023443-pvz7dll9	512	23	to	to	IN
cord-023443-pvz7dll9	512	24	composition	composition	NN
cord-023443-pvz7dll9	512	25	of	of	IN
cord-023443-pvz7dll9	512	26	gut	gut	NN
cord-023443-pvz7dll9	512	27	flora	flora	NNS
cord-023443-pvz7dll9	512	28	including	include	VBG
cord-023443-pvz7dll9	512	29	ingested	ingest	VBN
cord-023443-pvz7dll9	512	30	probiotics	probiotic	NNS
cord-023443-pvz7dll9	512	31	.	.	.
cord-023443-pvz7dll9	513	1	The	the	DT
cord-023443-pvz7dll9	513	2	intestinal	intestinal	JJ
cord-023443-pvz7dll9	513	3	micro	micro	NN
cord-023443-pvz7dll9	513	4	flora	flora	NNP
cord-023443-pvz7dll9	513	5	is	be	VBZ
cord-023443-pvz7dll9	513	6	indispensable	indispensable	JJ
cord-023443-pvz7dll9	513	7	in	in	IN
cord-023443-pvz7dll9	513	8	developing	develop	VBG
cord-023443-pvz7dll9	513	9	and	and	CC
cord-023443-pvz7dll9	513	10	maintaining	maintain	VBG
cord-023443-pvz7dll9	513	11	homeostasis	homeostasis	NN
cord-023443-pvz7dll9	513	12	of	of	IN
cord-023443-pvz7dll9	513	13	the	the	DT
cord-023443-pvz7dll9	513	14	gut	gut	NN
cord-023443-pvz7dll9	513	15	-	-	HYPH
cord-023443-pvz7dll9	513	16	associated	associate	VBN
cord-023443-pvz7dll9	513	17	immune	immune	JJ
cord-023443-pvz7dll9	513	18	system	system	NN
cord-023443-pvz7dll9	513	19	.	.	.
cord-023443-pvz7dll9	514	1	Evidence	evidence	NN
cord-023443-pvz7dll9	514	2	indicates	indicate	VBZ
cord-023443-pvz7dll9	514	3	that	that	IN
cord-023443-pvz7dll9	514	4	lactic	lactic	JJ
cord-023443-pvz7dll9	514	5	acid	acid	NN
cord-023443-pvz7dll9	514	6	bacteria	bacteria	NNS
cord-023443-pvz7dll9	514	7	(	(	-LRB-
cord-023443-pvz7dll9	514	8	LAB	lab	NN
cord-023443-pvz7dll9	514	9	)	)	-RRB-
cord-023443-pvz7dll9	514	10	,	,	,
cord-023443-pvz7dll9	514	11	e.g.	e.g.	IN
cord-023443-pvz7dll9	514	12	lactobacilli	lactobacilli	NN
cord-023443-pvz7dll9	514	13	and	and	CC
cord-023443-pvz7dll9	514	14	bifidobacteria	bifidobacteria	NNP
cord-023443-pvz7dll9	514	15	,	,	,
cord-023443-pvz7dll9	514	16	have	have	VBP
cord-023443-pvz7dll9	514	17	beneficial	beneficial	JJ
cord-023443-pvz7dll9	514	18	effects	effect	NNS
cord-023443-pvz7dll9	514	19	on	on	IN
cord-023443-pvz7dll9	514	20	the	the	DT
cord-023443-pvz7dll9	514	21	host	host	NN
cord-023443-pvz7dll9	514	22	.	.	.
cord-023443-pvz7dll9	515	1	Established	establish	VBN
cord-023443-pvz7dll9	515	2	health	health	NN
cord-023443-pvz7dll9	515	3	effects	effect	NNS
cord-023443-pvz7dll9	515	4	include	include	VBP
cord-023443-pvz7dll9	515	5	increased	increase	VBN
cord-023443-pvz7dll9	515	6	gut	gut	NN
cord-023443-pvz7dll9	515	7	maturation	maturation	NN
cord-023443-pvz7dll9	515	8	,	,	,
cord-023443-pvz7dll9	515	9	antagonisms	antagonism	NNS
cord-023443-pvz7dll9	515	10	towards	towards	IN
cord-023443-pvz7dll9	515	11	pathogens	pathogen	NNS
cord-023443-pvz7dll9	515	12	and	and	CC
cord-023443-pvz7dll9	515	13	immune	immune	JJ
cord-023443-pvz7dll9	515	14	modulation	modulation	NN
cord-023443-pvz7dll9	515	15	.	.	.
cord-023443-pvz7dll9	516	1	The	the	DT
cord-023443-pvz7dll9	516	2	objective	objective	NN
cord-023443-pvz7dll9	516	3	of	of	IN
cord-023443-pvz7dll9	516	4	this	this	DT
cord-023443-pvz7dll9	516	5	study	study	NN
cord-023443-pvz7dll9	516	6	is	be	VBZ
cord-023443-pvz7dll9	516	7	to	to	TO
cord-023443-pvz7dll9	516	8	evaluate	evaluate	VB
cord-023443-pvz7dll9	516	9	the	the	DT
cord-023443-pvz7dll9	516	10	immunomodulating	immunomodulate	VBG
cord-023443-pvz7dll9	516	11	properties	property	NNS
cord-023443-pvz7dll9	516	12	of	of	IN
cord-023443-pvz7dll9	516	13	a	a	DT
cord-023443-pvz7dll9	516	14	range	range	NN
cord-023443-pvz7dll9	516	15	of	of	IN
cord-023443-pvz7dll9	516	16	LAB	lab	NN
cord-023443-pvz7dll9	516	17	of	of	IN
cord-023443-pvz7dll9	516	18	human	human	JJ
cord-023443-pvz7dll9	516	19	origin	origin	NN
cord-023443-pvz7dll9	516	20	.	.	.
cord-023443-pvz7dll9	517	1	As	as	IN
cord-023443-pvz7dll9	517	2	dendritic	dendritic	JJ
cord-023443-pvz7dll9	517	3	cells	cell	NNS
cord-023443-pvz7dll9	517	4	(	(	-LRB-
cord-023443-pvz7dll9	517	5	DCs	DCs	NNP
cord-023443-pvz7dll9	517	6	)	)	-RRB-
cord-023443-pvz7dll9	517	7	play	play	VBP
cord-023443-pvz7dll9	517	8	a	a	DT
cord-023443-pvz7dll9	517	9	pivotal	pivotal	JJ
cord-023443-pvz7dll9	517	10	role	role	NN
cord-023443-pvz7dll9	517	11	in	in	IN
cord-023443-pvz7dll9	517	12	the	the	DT
cord-023443-pvz7dll9	517	13	balance	balance	NN
cord-023443-pvz7dll9	517	14	between	between	IN
cord-023443-pvz7dll9	517	15	tolerance	tolerance	NN
cord-023443-pvz7dll9	517	16	and	and	CC
cord-023443-pvz7dll9	517	17	immunity	immunity	NN
cord-023443-pvz7dll9	517	18	to	to	IN
cord-023443-pvz7dll9	517	19	commensal	commensal	JJ
cord-023443-pvz7dll9	517	20	microorganisms	microorganism	NNS
cord-023443-pvz7dll9	517	21	,	,	,
cord-023443-pvz7dll9	517	22	in	in	IN
cord-023443-pvz7dll9	517	23	vitro	vitro	FW
cord-023443-pvz7dll9	517	24	-	-	HYPH
cord-023443-pvz7dll9	517	25	generated	generate	VBN
cord-023443-pvz7dll9	517	26	immature	immature	JJ
cord-023443-pvz7dll9	517	27	DCs	dc	NNS
cord-023443-pvz7dll9	517	28	serve	serve	VBP
cord-023443-pvz7dll9	517	29	as	as	IN
cord-023443-pvz7dll9	517	30	a	a	DT
cord-023443-pvz7dll9	517	31	suitable	suitable	JJ
cord-023443-pvz7dll9	517	32	model	model	NN
cord-023443-pvz7dll9	517	33	for	for	IN
cord-023443-pvz7dll9	517	34	studying	study	VBG
cord-023443-pvz7dll9	517	35	the	the	DT
cord-023443-pvz7dll9	517	36	immunomodulating	immunomodulating	JJ
cord-023443-pvz7dll9	517	37	effects	effect	NNS
cord-023443-pvz7dll9	517	38	of	of	IN
cord-023443-pvz7dll9	517	39	lab	lab	NN
cord-023443-pvz7dll9	517	40	.	.	.
cord-023443-pvz7dll9	518	1	Human	human	JJ
cord-023443-pvz7dll9	518	2	immature	immature	JJ
cord-023443-pvz7dll9	518	3	DCs	dc	NNS
cord-023443-pvz7dll9	518	4	were	be	VBD
cord-023443-pvz7dll9	518	5	generated	generate	VBN
cord-023443-pvz7dll9	518	6	in	in	IN
cord-023443-pvz7dll9	518	7	vitro	vitro	FW
cord-023443-pvz7dll9	518	8	from	from	IN
cord-023443-pvz7dll9	518	9	monocytes	monocyte	NNS
cord-023443-pvz7dll9	518	10	and	and	CC
cord-023443-pvz7dll9	518	11	exposed	expose	VBN
cord-023443-pvz7dll9	518	12	to	to	IN
cord-023443-pvz7dll9	518	13	lethally	lethally	RB
cord-023443-pvz7dll9	518	14	UV	uv	NN
cord-023443-pvz7dll9	518	15	-	-	HYPH
cord-023443-pvz7dll9	518	16	irradiated	irradiate	VBN
cord-023443-pvz7dll9	518	17	LAB	lab	NN
cord-023443-pvz7dll9	518	18	.	.	.
cord-023443-pvz7dll9	519	1	The	the	DT
cord-023443-pvz7dll9	519	2	effect	effect	NN
cord-023443-pvz7dll9	519	3	of	of	IN
cord-023443-pvz7dll9	519	4	various	various	JJ
cord-023443-pvz7dll9	519	5	species	specie	NNS
cord-023443-pvz7dll9	519	6	of	of	IN
cord-023443-pvz7dll9	519	7	LAB	lab	NN
cord-023443-pvz7dll9	519	8	on	on	IN
cord-023443-pvz7dll9	519	9	DCs	dc	NNS
cord-023443-pvz7dll9	519	10	in	in	IN
cord-023443-pvz7dll9	519	11	direct	direct	JJ
cord-023443-pvz7dll9	519	12	contact	contact	NN
cord-023443-pvz7dll9	519	13	was	be	VBD
cord-023443-pvz7dll9	519	14	evaluated	evaluate	VBN
cord-023443-pvz7dll9	519	15	.	.	.
cord-023443-pvz7dll9	520	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	520	2	,	,	,
cord-023443-pvz7dll9	520	3	the	the	DT
cord-023443-pvz7dll9	520	4	maturation	maturation	NN
cord-023443-pvz7dll9	520	5	pattern	pattern	NN
cord-023443-pvz7dll9	520	6	of	of	IN
cord-023443-pvz7dll9	520	7	DCs	dc	NNS
cord-023443-pvz7dll9	520	8	separated	separate	VBD
cord-023443-pvz7dll9	520	9	from	from	IN
cord-023443-pvz7dll9	520	10	the	the	DT
cord-023443-pvz7dll9	520	11	bacteria	bacteria	NNS
cord-023443-pvz7dll9	520	12	by	by	IN
cord-023443-pvz7dll9	520	13	an	an	DT
cord-023443-pvz7dll9	520	14	epithelial	epithelial	JJ
cord-023443-pvz7dll9	520	15	cell	cell	NN
cord-023443-pvz7dll9	520	16	layer	layer	NN
cord-023443-pvz7dll9	520	17	(	(	-LRB-
cord-023443-pvz7dll9	520	18	CaCo-2	CaCo-2	NNP
cord-023443-pvz7dll9	520	19	cells	cell	NNS
cord-023443-pvz7dll9	520	20	)	)	-RRB-
cord-023443-pvz7dll9	520	21	,	,	,
cord-023443-pvz7dll9	520	22	which	which	WDT
cord-023443-pvz7dll9	520	23	should	should	MD
cord-023443-pvz7dll9	520	24	mimic	mimic	VB
cord-023443-pvz7dll9	520	25	the	the	DT
cord-023443-pvz7dll9	520	26	intestinal	intestinal	JJ
cord-023443-pvz7dll9	520	27	environment	environment	NN
cord-023443-pvz7dll9	520	28	,	,	,
cord-023443-pvz7dll9	520	29	was	be	VBD
cord-023443-pvz7dll9	520	30	studied	study	VBN
cord-023443-pvz7dll9	520	31	.	.	.
cord-023443-pvz7dll9	521	1	Cytokine	cytokine	NN
cord-023443-pvz7dll9	521	2	secretion	secretion	NN
cord-023443-pvz7dll9	521	3	(	(	-LRB-
cord-023443-pvz7dll9	521	4	IL-12	IL-12	NNP
cord-023443-pvz7dll9	521	5	,	,	,
cord-023443-pvz7dll9	521	6	IL-10	IL-10	NNP
cord-023443-pvz7dll9	521	7	and	and	CC
cord-023443-pvz7dll9	521	8	TNF	TNF	NNP
cord-023443-pvz7dll9	521	9	-	-	HYPH
cord-023443-pvz7dll9	521	10	a	a	LS
cord-023443-pvz7dll9	521	11	)	)	-RRB-
cord-023443-pvz7dll9	521	12	and	and	CC
cord-023443-pvz7dll9	521	13	upregulation	upregulation	NN
cord-023443-pvz7dll9	521	14	of	of	IN
cord-023443-pvz7dll9	521	15	maturation	maturation	NN
cord-023443-pvz7dll9	521	16	surface	surface	NN
cord-023443-pvz7dll9	521	17	markers	marker	NNS
cord-023443-pvz7dll9	521	18	on	on	IN
cord-023443-pvz7dll9	521	19	DCs	DCs	NNP
cord-023443-pvz7dll9	521	20	(	(	-LRB-
cord-023443-pvz7dll9	521	21	CD83	CD83	NNP
cord-023443-pvz7dll9	521	22	and	and	CC
cord-023443-pvz7dll9	521	23	CD86	CD86	NNP
cord-023443-pvz7dll9	521	24	)	)	-RRB-
cord-023443-pvz7dll9	521	25	was	be	VBD
cord-023443-pvz7dll9	521	26	measured	measure	VBN
cord-023443-pvz7dll9	521	27	.	.	.
cord-023443-pvz7dll9	522	1	Different	different	JJ
cord-023443-pvz7dll9	522	2	LAB	lab	NN
cord-023443-pvz7dll9	522	3	induced	induce	VBN
cord-023443-pvz7dll9	522	4	diverse	diverse	JJ
cord-023443-pvz7dll9	522	5	cytokine	cytokine	NN
cord-023443-pvz7dll9	522	6	responses	response	NNS
cord-023443-pvz7dll9	522	7	.	.	.
cord-023443-pvz7dll9	523	1	Some	some	DT
cord-023443-pvz7dll9	523	2	strains	strain	NNS
cord-023443-pvz7dll9	523	3	were	be	VBD
cord-023443-pvz7dll9	523	4	strong	strong	JJ
cord-023443-pvz7dll9	523	5	IL-12	IL-12	NNP
cord-023443-pvz7dll9	523	6	and	and	CC
cord-023443-pvz7dll9	523	7	TNF	TNF	NNP
cord-023443-pvz7dll9	523	8	-	-	,
cord-023443-pvz7dll9	523	9	a	a	DT
cord-023443-pvz7dll9	523	10	inducers	inducer	NNS
cord-023443-pvz7dll9	523	11	and	and	CC
cord-023443-pvz7dll9	523	12	others	other	NNS
cord-023443-pvz7dll9	523	13	weak	weak	JJ
cord-023443-pvz7dll9	523	14	.	.	.
cord-023443-pvz7dll9	524	1	All	all	DT
cord-023443-pvz7dll9	524	2	strains	strain	NNS
cord-023443-pvz7dll9	524	3	induced	induce	VBN
cord-023443-pvz7dll9	524	4	IL-10	IL-10	NNP
cord-023443-pvz7dll9	524	5	.	.	.
cord-023443-pvz7dll9	525	1	Different	different	JJ
cord-023443-pvz7dll9	525	2	LAB	lab	NN
cord-023443-pvz7dll9	525	3	also	also	RB
cord-023443-pvz7dll9	525	4	differentially	differentially	RB
cord-023443-pvz7dll9	525	5	modulated	modulate	VBN
cord-023443-pvz7dll9	525	6	expression	expression	NN
cord-023443-pvz7dll9	525	7	of	of	IN
cord-023443-pvz7dll9	525	8	CD83	CD83	NNP
cord-023443-pvz7dll9	525	9	and	and	CC
cord-023443-pvz7dll9	525	10	CD86	CD86	NNP
cord-023443-pvz7dll9	525	11	on	on	IN
cord-023443-pvz7dll9	525	12	DCs	dc	NNS
cord-023443-pvz7dll9	525	13	.	.	.
cord-023443-pvz7dll9	526	1	Although	although	IN
cord-023443-pvz7dll9	526	2	some	some	DT
cord-023443-pvz7dll9	526	3	variation	variation	NN
cord-023443-pvz7dll9	526	4	in	in	IN
cord-023443-pvz7dll9	526	5	the	the	DT
cord-023443-pvz7dll9	526	6	response	response	NN
cord-023443-pvz7dll9	526	7	to	to	IN
cord-023443-pvz7dll9	526	8	LAB	LAB	NNP
cord-023443-pvz7dll9	526	9	of	of	IN
cord-023443-pvz7dll9	526	10	DCs	dc	NNS
cord-023443-pvz7dll9	526	11	generated	generate	VBN
cord-023443-pvz7dll9	526	12	from	from	IN
cord-023443-pvz7dll9	526	13	different	different	JJ
cord-023443-pvz7dll9	526	14	blood	blood	NN
cord-023443-pvz7dll9	526	15	donors	donor	NNS
cord-023443-pvz7dll9	526	16	was	be	VBD
cord-023443-pvz7dll9	526	17	observed	observe	VBN
cord-023443-pvz7dll9	526	18	,	,	,
cord-023443-pvz7dll9	526	19	general	general	JJ
cord-023443-pvz7dll9	526	20	differences	difference	NNS
cord-023443-pvz7dll9	526	21	in	in	IN
cord-023443-pvz7dll9	526	22	the	the	DT
cord-023443-pvz7dll9	526	23	effect	effect	NN
cord-023443-pvz7dll9	526	24	of	of	IN
cord-023443-pvz7dll9	526	25	the	the	DT
cord-023443-pvz7dll9	526	26	various	various	JJ
cord-023443-pvz7dll9	526	27	LAB	lab	NN
cord-023443-pvz7dll9	526	28	was	be	VBD
cord-023443-pvz7dll9	526	29	revealed	reveal	VBN
cord-023443-pvz7dll9	526	30	.	.	.
cord-023443-pvz7dll9	527	1	Experiments	experiment	NNS
cord-023443-pvz7dll9	527	2	with	with	IN
cord-023443-pvz7dll9	527	3	the	the	DT
cord-023443-pvz7dll9	527	4	DC	DC	NNP
cord-023443-pvz7dll9	527	5	CaCo-2	CaCo-2	NNP
cord-023443-pvz7dll9	527	6	coculture	coculture	NN
cord-023443-pvz7dll9	527	7	system	system	NN
cord-023443-pvz7dll9	527	8	are	be	VBP
cord-023443-pvz7dll9	527	9	ongoing	ongoing	JJ
cord-023443-pvz7dll9	527	10	.	.	.
cord-023443-pvz7dll9	528	1	Different	different	JJ
cord-023443-pvz7dll9	528	2	species	specie	NNS
cord-023443-pvz7dll9	528	3	of	of	IN
cord-023443-pvz7dll9	528	4	LAB	lab	NN
cord-023443-pvz7dll9	528	5	differentially	differentially	RB
cord-023443-pvz7dll9	528	6	affect	affect	VBP
cord-023443-pvz7dll9	528	7	DC	DC	NNP
cord-023443-pvz7dll9	528	8	maturation	maturation	NN
cord-023443-pvz7dll9	528	9	;	;	:
cord-023443-pvz7dll9	528	10	this	this	DT
cord-023443-pvz7dll9	528	11	suggets	sugget	VBZ
cord-023443-pvz7dll9	528	12	that	that	IN
cord-023443-pvz7dll9	528	13	the	the	DT
cord-023443-pvz7dll9	528	14	gut	gut	NN
cord-023443-pvz7dll9	528	15	flora	flora	NN
cord-023443-pvz7dll9	528	16	plays	play	VBZ
cord-023443-pvz7dll9	528	17	a	a	DT
cord-023443-pvz7dll9	528	18	pivotal	pivotal	JJ
cord-023443-pvz7dll9	528	19	role	role	NN
cord-023443-pvz7dll9	528	20	in	in	IN
cord-023443-pvz7dll9	528	21	polarization	polarization	NN
cord-023443-pvz7dll9	528	22	of	of	IN
cord-023443-pvz7dll9	528	23	the	the	DT
cord-023443-pvz7dll9	528	24	immune	immune	JJ
cord-023443-pvz7dll9	528	25	response	response	NN
cord-023443-pvz7dll9	528	26	.	.	.
cord-023443-pvz7dll9	529	1	Natural	natural	JJ
cord-023443-pvz7dll9	529	2	killer	killer	NN
cord-023443-pvz7dll9	529	3	(	(	-LRB-
cord-023443-pvz7dll9	529	4	NK	NK	NNP
cord-023443-pvz7dll9	529	5	)	)	-RRB-
cord-023443-pvz7dll9	529	6	cells	cell	NNS
cord-023443-pvz7dll9	529	7	are	be	VBP
cord-023443-pvz7dll9	529	8	cells	cell	NNS
cord-023443-pvz7dll9	529	9	of	of	IN
cord-023443-pvz7dll9	529	10	the	the	DT
cord-023443-pvz7dll9	529	11	nonspecific	nonspecific	JJ
cord-023443-pvz7dll9	529	12	immune	immune	JJ
cord-023443-pvz7dll9	529	13	system	system	NN
cord-023443-pvz7dll9	529	14	lysing	lyse	VBG
cord-023443-pvz7dll9	529	15	altered	alter	VBD
cord-023443-pvz7dll9	529	16	self	self	NN
cord-023443-pvz7dll9	529	17	-	-	HYPH
cord-023443-pvz7dll9	529	18	cells	cell	NNS
cord-023443-pvz7dll9	529	19	.	.	.
cord-023443-pvz7dll9	530	1	A	a	DT
cord-023443-pvz7dll9	530	2	noncytolytic	noncytolytic	JJ
cord-023443-pvz7dll9	530	3	subset	subset	VBN
cord-023443-pvz7dll9	530	4	of	of	IN
cord-023443-pvz7dll9	530	5	NK	NK	NNP
cord-023443-pvz7dll9	530	6	cells	cell	NNS
cord-023443-pvz7dll9	530	7	may	may	MD
cord-023443-pvz7dll9	530	8	serve	serve	VB
cord-023443-pvz7dll9	530	9	a	a	DT
cord-023443-pvz7dll9	530	10	regulatory	regulatory	JJ
cord-023443-pvz7dll9	530	11	role	role	NN
cord-023443-pvz7dll9	530	12	by	by	IN
cord-023443-pvz7dll9	530	13	secreting	secrete	VBG
cord-023443-pvz7dll9	530	14	cytokines	cytokine	NNS
cord-023443-pvz7dll9	530	15	.	.	.
cord-023443-pvz7dll9	531	1	Bacteria	Bacteria	NNS
cord-023443-pvz7dll9	531	2	translocating	translocate	VBG
cord-023443-pvz7dll9	531	3	across	across	IN
cord-023443-pvz7dll9	531	4	the	the	DT
cord-023443-pvz7dll9	531	5	gastrointestinal	gastrointestinal	JJ
cord-023443-pvz7dll9	531	6	mucosa	mucosa	NN
cord-023443-pvz7dll9	531	7	are	be	VBP
cord-023443-pvz7dll9	531	8	presumed	presume	VBN
cord-023443-pvz7dll9	531	9	to	to	TO
cord-023443-pvz7dll9	531	10	gain	gain	VB
cord-023443-pvz7dll9	531	11	access	access	NN
cord-023443-pvz7dll9	531	12	to	to	IN
cord-023443-pvz7dll9	531	13	NK	NK	NNP
cord-023443-pvz7dll9	531	14	cells	cell	NNS
cord-023443-pvz7dll9	531	15	,	,	,
cord-023443-pvz7dll9	531	16	as	as	IN
cord-023443-pvz7dll9	531	17	consumption	consumption	NN
cord-023443-pvz7dll9	531	18	of	of	IN
cord-023443-pvz7dll9	531	19	certain	certain	JJ
cord-023443-pvz7dll9	531	20	lactic	lactic	JJ
cord-023443-pvz7dll9	531	21	acid	acid	NN
cord-023443-pvz7dll9	531	22	bacteria	bacteria	NNS
cord-023443-pvz7dll9	531	23	has	have	VBZ
cord-023443-pvz7dll9	531	24	been	be	VBN
cord-023443-pvz7dll9	531	25	shown	show	VBN
cord-023443-pvz7dll9	531	26	to	to	TO
cord-023443-pvz7dll9	531	27	increase	increase	VB
cord-023443-pvz7dll9	531	28	in	in	IN
cord-023443-pvz7dll9	531	29	vivo	vivo	NN
cord-023443-pvz7dll9	531	30	NK	nk	NN
cord-023443-pvz7dll9	531	31	cytotoxicity	cytotoxicity	NN
cord-023443-pvz7dll9	531	32	.	.	.
cord-023443-pvz7dll9	532	1	Here	here	RB
cord-023443-pvz7dll9	532	2	,	,	,
cord-023443-pvz7dll9	532	3	we	-PRON-	PRP
cord-023443-pvz7dll9	532	4	investigated	investigate	VBD
cord-023443-pvz7dll9	532	5	how	how	WRB
cord-023443-pvz7dll9	532	6	human	human	JJ
cord-023443-pvz7dll9	532	7	gut	gut	NN
cord-023443-pvz7dll9	532	8	flora	flora	NNS
cord-023443-pvz7dll9	532	9	-	-	HYPH
cord-023443-pvz7dll9	532	10	derived	derive	VBN
cord-023443-pvz7dll9	532	11	lactobacilli	lactobacilli	NN
cord-023443-pvz7dll9	532	12	affect	affect	VBP
cord-023443-pvz7dll9	532	13	NK	NK	NNP
cord-023443-pvz7dll9	532	14	cells	cell	NNS
cord-023443-pvz7dll9	532	15	in	in	IN
cord-023443-pvz7dll9	532	16	vitro	vitro	FW
cord-023443-pvz7dll9	532	17	,	,	,
cord-023443-pvz7dll9	532	18	by	by	IN
cord-023443-pvz7dll9	532	19	measuring	measure	VBG
cord-023443-pvz7dll9	532	20	proliferation	proliferation	NN
cord-023443-pvz7dll9	532	21	and	and	CC
cord-023443-pvz7dll9	532	22	IFN	IFN	NNP
cord-023443-pvz7dll9	532	23	-	-	HYPH
cord-023443-pvz7dll9	532	24	g	g	NN
cord-023443-pvz7dll9	532	25	production	production	NN
cord-023443-pvz7dll9	532	26	of	of	IN
cord-023443-pvz7dll9	532	27	human	human	JJ
cord-023443-pvz7dll9	532	28	NK	NK	NNP
cord-023443-pvz7dll9	532	29	cells	cell	NNS
cord-023443-pvz7dll9	532	30	upon	upon	IN
cord-023443-pvz7dll9	532	31	bacterial	bacterial	JJ
cord-023443-pvz7dll9	532	32	stimulation	stimulation	NN
cord-023443-pvz7dll9	532	33	.	.	.
cord-023443-pvz7dll9	533	1	CD3	CD3	NNP
cord-023443-pvz7dll9	533	2	-CD56	-CD56	NNP
cord-023443-pvz7dll9	533	3	þ	þ	NNP
cord-023443-pvz7dll9	533	4	NK	NK	NNP
cord-023443-pvz7dll9	533	5	cells	cell	NNS
cord-023443-pvz7dll9	533	6	were	be	VBD
cord-023443-pvz7dll9	533	7	isolated	isolate	VBN
cord-023443-pvz7dll9	533	8	from	from	IN
cord-023443-pvz7dll9	533	9	buffy	buffy	NNP
cord-023443-pvz7dll9	533	10	coats	coat	NNS
cord-023443-pvz7dll9	533	11	by	by	IN
cord-023443-pvz7dll9	533	12	negative	negative	JJ
cord-023443-pvz7dll9	533	13	isolation	isolation	NN
cord-023443-pvz7dll9	533	14	using	use	VBG
cord-023443-pvz7dll9	533	15	non	non	JJ
cord-023443-pvz7dll9	533	16	-	-	JJ
cord-023443-pvz7dll9	533	17	NK	nk	JJ
cord-023443-pvz7dll9	533	18	lineage	lineage	NN
cord-023443-pvz7dll9	533	19	-	-	HYPH
cord-023443-pvz7dll9	533	20	specific	specific	JJ
cord-023443-pvz7dll9	533	21	antibodies	antibody	NNS
cord-023443-pvz7dll9	533	22	and	and	CC
cord-023443-pvz7dll9	533	23	magnetic	magnetic	JJ
cord-023443-pvz7dll9	533	24	beads	bead	NNS
cord-023443-pvz7dll9	533	25	.	.	.
cord-023443-pvz7dll9	534	1	NK	NK	NNP
cord-023443-pvz7dll9	534	2	cells	cell	NNS
cord-023443-pvz7dll9	534	3	were	be	VBD
cord-023443-pvz7dll9	534	4	incubated	incubate	VBN
cord-023443-pvz7dll9	534	5	with	with	IN
cord-023443-pvz7dll9	534	6	10mg	10mg	NNP
cord-023443-pvz7dll9	534	7	/	/	SYM
cord-023443-pvz7dll9	534	8	ml	ml	NN
cord-023443-pvz7dll9	534	9	UV	uv	NN
cord-023443-pvz7dll9	534	10	-	-	HYPH
cord-023443-pvz7dll9	534	11	inactivated	inactivate	VBN
cord-023443-pvz7dll9	534	12	bacteria	bacteria	NNS
cord-023443-pvz7dll9	534	13	or	or	CC
cord-023443-pvz7dll9	534	14	10mg	10mg	NN
cord-023443-pvz7dll9	534	15	/	/	SYM
cord-023443-pvz7dll9	534	16	ml	ml	NN
cord-023443-pvz7dll9	534	17	phytohemagglutinin	phytohemagglutinin	NNP
cord-023443-pvz7dll9	534	18	(	(	-LRB-
cord-023443-pvz7dll9	534	19	PHA	PHA	NNP
cord-023443-pvz7dll9	534	20	)	)	-RRB-
cord-023443-pvz7dll9	534	21	for	for	IN
cord-023443-pvz7dll9	534	22	4	4	CD
cord-023443-pvz7dll9	534	23	days	day	NNS
cord-023443-pvz7dll9	534	24	.	.	.
cord-023443-pvz7dll9	535	1	Proliferation	proliferation	NN
cord-023443-pvz7dll9	535	2	was	be	VBD
cord-023443-pvz7dll9	535	3	assessed	assess	VBN
cord-023443-pvz7dll9	535	4	by	by	IN
cord-023443-pvz7dll9	535	5	incorporation	incorporation	NN
cord-023443-pvz7dll9	535	6	of	of	IN
cord-023443-pvz7dll9	535	7	radioactive	radioactive	JJ
cord-023443-pvz7dll9	535	8	thymidine	thymidine	NN
cord-023443-pvz7dll9	535	9	into	into	IN
cord-023443-pvz7dll9	535	10	NK	nk	NN
cord-023443-pvz7dll9	535	11	-	-	HYPH
cord-023443-pvz7dll9	535	12	cell	cell	NN
cord-023443-pvz7dll9	535	13	DNA	dna	NN
cord-023443-pvz7dll9	535	14	.	.	.
cord-023443-pvz7dll9	536	1	The	the	DT
cord-023443-pvz7dll9	536	2	IFN	IFN	NNP
cord-023443-pvz7dll9	536	3	-	-	HYPH
cord-023443-pvz7dll9	536	4	g	g	NN
cord-023443-pvz7dll9	536	5	concentration	concentration	NN
cord-023443-pvz7dll9	536	6	was	be	VBD
cord-023443-pvz7dll9	536	7	measured	measure	VBN
cord-023443-pvz7dll9	536	8	by	by	IN
cord-023443-pvz7dll9	536	9	ELISA	ELISA	NNP
cord-023443-pvz7dll9	536	10	.	.	.
cord-023443-pvz7dll9	537	1	Incubation	Incubation	NNP
cord-023443-pvz7dll9	537	2	of	of	IN
cord-023443-pvz7dll9	537	3	NK	NK	NNP
cord-023443-pvz7dll9	537	4	cells	cell	NNS
cord-023443-pvz7dll9	537	5	with	with	IN
cord-023443-pvz7dll9	537	6	a	a	DT
cord-023443-pvz7dll9	537	7	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	537	8	acidophilus	acidophilus	NN
cord-023443-pvz7dll9	537	9	strain	strain	NN
cord-023443-pvz7dll9	537	10	increased	increase	VBD
cord-023443-pvz7dll9	537	11	the	the	DT
cord-023443-pvz7dll9	537	12	proliferation	proliferation	NN
cord-023443-pvz7dll9	537	13	of	of	IN
cord-023443-pvz7dll9	537	14	the	the	DT
cord-023443-pvz7dll9	537	15	NK	NK	NNP
cord-023443-pvz7dll9	537	16	cells	cell	NNS
cord-023443-pvz7dll9	537	17	and	and	CC
cord-023443-pvz7dll9	537	18	induced	induce	VBD
cord-023443-pvz7dll9	537	19	IFN	IFN	NNP
cord-023443-pvz7dll9	537	20	-	-	HYPH
cord-023443-pvz7dll9	537	21	g	g	NN
cord-023443-pvz7dll9	537	22	production	production	NN
cord-023443-pvz7dll9	537	23	,	,	,
cord-023443-pvz7dll9	537	24	both	both	DT
cord-023443-pvz7dll9	537	25	to	to	IN
cord-023443-pvz7dll9	537	26	levels	level	NNS
cord-023443-pvz7dll9	537	27	comparable	comparable	JJ
cord-023443-pvz7dll9	537	28	to	to	IN
cord-023443-pvz7dll9	537	29	PHA	PHA	NNP
cord-023443-pvz7dll9	537	30	stimulation	stimulation	NN
cord-023443-pvz7dll9	537	31	.	.	.
cord-023443-pvz7dll9	538	1	The	the	DT
cord-023443-pvz7dll9	538	2	proliferative	proliferative	JJ
cord-023443-pvz7dll9	538	3	response	response	NN
cord-023443-pvz7dll9	538	4	was	be	VBD
cord-023443-pvz7dll9	538	5	further	further	RB
cord-023443-pvz7dll9	538	6	enhanced	enhance	VBN
cord-023443-pvz7dll9	538	7	with	with	IN
cord-023443-pvz7dll9	538	8	autologous	autologous	JJ
cord-023443-pvz7dll9	538	9	monocytes	monocyte	NNS
cord-023443-pvz7dll9	538	10	present	present	JJ
cord-023443-pvz7dll9	538	11	,	,	,
cord-023443-pvz7dll9	538	12	probably	probably	RB
cord-023443-pvz7dll9	538	13	because	because	IN
cord-023443-pvz7dll9	538	14	cytokines	cytokine	NNS
cord-023443-pvz7dll9	538	15	,	,	,
cord-023443-pvz7dll9	538	16	secreted	secrete	VBN
cord-023443-pvz7dll9	538	17	by	by	IN
cord-023443-pvz7dll9	538	18	monocytes	monocyte	NNS
cord-023443-pvz7dll9	538	19	having	have	VBG
cord-023443-pvz7dll9	538	20	engulfed	engulf	VBN
cord-023443-pvz7dll9	538	21	bacteria	bacteria	NNS
cord-023443-pvz7dll9	538	22	,	,	,
cord-023443-pvz7dll9	538	23	stimulated	stimulate	VBD
cord-023443-pvz7dll9	538	24	the	the	DT
cord-023443-pvz7dll9	538	25	NK	NK	NNP
cord-023443-pvz7dll9	538	26	cells	cell	NNS
cord-023443-pvz7dll9	538	27	.	.	.
cord-023443-pvz7dll9	539	1	In	in	IN
cord-023443-pvz7dll9	539	2	contrast	contrast	NN
cord-023443-pvz7dll9	539	3	,	,	,
cord-023443-pvz7dll9	539	4	a	a	DT
cord-023443-pvz7dll9	539	5	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	539	6	paracasei	paracasei	NN
cord-023443-pvz7dll9	539	7	strain	strain	NN
cord-023443-pvz7dll9	539	8	caused	cause	VBD
cord-023443-pvz7dll9	539	9	the	the	DT
cord-023443-pvz7dll9	539	10	NK	NK	NNP
cord-023443-pvz7dll9	539	11	cells	cell	NNS
cord-023443-pvz7dll9	539	12	to	to	TO
cord-023443-pvz7dll9	539	13	proliferate	proliferate	VB
cord-023443-pvz7dll9	539	14	only	only	RB
cord-023443-pvz7dll9	539	15	in	in	IN
cord-023443-pvz7dll9	539	16	the	the	DT
cord-023443-pvz7dll9	539	17	presence	presence	NN
cord-023443-pvz7dll9	539	18	of	of	IN
cord-023443-pvz7dll9	539	19	monocytes	monocyte	NNS
cord-023443-pvz7dll9	539	20	.	.	.
cord-023443-pvz7dll9	540	1	These	these	DT
cord-023443-pvz7dll9	540	2	results	result	NNS
cord-023443-pvz7dll9	540	3	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	540	4	that	that	IN
cord-023443-pvz7dll9	540	5	various	various	JJ
cord-023443-pvz7dll9	540	6	strains	strain	NNS
cord-023443-pvz7dll9	540	7	of	of	IN
cord-023443-pvz7dll9	540	8	lactobacilli	lactobacillus	NNS
cord-023443-pvz7dll9	540	9	have	have	VBP
cord-023443-pvz7dll9	540	10	the	the	DT
cord-023443-pvz7dll9	540	11	capacity	capacity	NN
cord-023443-pvz7dll9	540	12	to	to	TO
cord-023443-pvz7dll9	540	13	activate	activate	VB
cord-023443-pvz7dll9	540	14	NK	NK	NNP
cord-023443-pvz7dll9	540	15	cells	cell	NNS
cord-023443-pvz7dll9	540	16	in	in	IN
cord-023443-pvz7dll9	540	17	vitro	vitro	FW
cord-023443-pvz7dll9	540	18	,	,	,
cord-023443-pvz7dll9	540	19	in	in	IN
cord-023443-pvz7dll9	540	20	a	a	DT
cord-023443-pvz7dll9	540	21	monocyte	monocyte	NN
cord-023443-pvz7dll9	540	22	-	-	HYPH
cord-023443-pvz7dll9	540	23	dependent	dependent	JJ
cord-023443-pvz7dll9	540	24	or	or	CC
cord-023443-pvz7dll9	540	25	-independent	-independent	JJ
cord-023443-pvz7dll9	540	26	way	way	NN
cord-023443-pvz7dll9	540	27	.	.	.
cord-023443-pvz7dll9	541	1	Hence	hence	RB
cord-023443-pvz7dll9	541	2	,	,	,
cord-023443-pvz7dll9	541	3	the	the	DT
cord-023443-pvz7dll9	541	4	encounter	encounter	NN
cord-023443-pvz7dll9	541	5	of	of	IN
cord-023443-pvz7dll9	541	6	NK	NK	NNP
cord-023443-pvz7dll9	541	7	cells	cell	NNS
cord-023443-pvz7dll9	541	8	with	with	IN
cord-023443-pvz7dll9	541	9	lactic	lactic	JJ
cord-023443-pvz7dll9	541	10	acid	acid	NN
cord-023443-pvz7dll9	541	11	bacteria	bacteria	NNS
cord-023443-pvz7dll9	541	12	will	will	MD
cord-023443-pvz7dll9	541	13	affect	affect	VB
cord-023443-pvz7dll9	541	14	NK	NK	NNP
cord-023443-pvz7dll9	541	15	-	-	HYPH
cord-023443-pvz7dll9	541	16	cell	cell	NN
cord-023443-pvz7dll9	541	17	activation	activation	NN
cord-023443-pvz7dll9	541	18	.	.	.
cord-023443-pvz7dll9	542	1	Such	such	JJ
cord-023443-pvz7dll9	542	2	activation	activation	NN
cord-023443-pvz7dll9	542	3	of	of	IN
cord-023443-pvz7dll9	542	4	NK	NK	NNP
cord-023443-pvz7dll9	542	5	cells	cell	NNS
cord-023443-pvz7dll9	542	6	may	may	MD
cord-023443-pvz7dll9	542	7	potentially	potentially	RB
cord-023443-pvz7dll9	542	8	skew	skew	VB
cord-023443-pvz7dll9	542	9	an	an	DT
cord-023443-pvz7dll9	542	10	on	on	RB
cord-023443-pvz7dll9	542	11	-	-	HYPH
cord-023443-pvz7dll9	542	12	going	going	NN
cord-023443-pvz7dll9	542	13	or	or	CC
cord-023443-pvz7dll9	542	14	subsequent	subsequent	JJ
cord-023443-pvz7dll9	542	15	immune	immune	JJ
cord-023443-pvz7dll9	542	16	response	response	NN
cord-023443-pvz7dll9	542	17	towards	towards	IN
cord-023443-pvz7dll9	542	18	a	a	DT
cord-023443-pvz7dll9	542	19	Th1	th1	CD
cord-023443-pvz7dll9	542	20	response	response	NN
cord-023443-pvz7dll9	542	21	.	.	.
cord-023443-pvz7dll9	543	1	Lactobacilli	Lactobacilli	NNP
cord-023443-pvz7dll9	543	2	are	be	VBP
cord-023443-pvz7dll9	543	3	nonpathogenic	nonpathogenic	NNP
cord-023443-pvz7dll9	543	4	gram	gram	NN
cord-023443-pvz7dll9	543	5	-	-	HYPH
cord-023443-pvz7dll9	543	6	positive	positive	JJ
cord-023443-pvz7dll9	543	7	inhabitants	inhabitant	NNS
cord-023443-pvz7dll9	543	8	of	of	IN
cord-023443-pvz7dll9	543	9	the	the	DT
cord-023443-pvz7dll9	543	10	normal	normal	JJ
cord-023443-pvz7dll9	543	11	human	human	JJ
cord-023443-pvz7dll9	543	12	intestine	intestine	NN
cord-023443-pvz7dll9	543	13	known	know	VBN
cord-023443-pvz7dll9	543	14	for	for	IN
cord-023443-pvz7dll9	543	15	their	-PRON-	PRP$
cord-023443-pvz7dll9	543	16	healthpromoting	healthpromote	VBG
cord-023443-pvz7dll9	543	17	effects	effect	NNS
cord-023443-pvz7dll9	543	18	.	.	.
cord-023443-pvz7dll9	544	1	In	in	IN
cord-023443-pvz7dll9	544	2	our	-PRON-	PRP$
cord-023443-pvz7dll9	544	3	earlier	early	JJR
cord-023443-pvz7dll9	544	4	work	work	NN
cord-023443-pvz7dll9	544	5	,	,	,
cord-023443-pvz7dll9	544	6	it	-PRON-	PRP
cord-023443-pvz7dll9	544	7	is	be	VBZ
cord-023443-pvz7dll9	544	8	shown	show	VBN
cord-023443-pvz7dll9	544	9	that	that	IN
cord-023443-pvz7dll9	544	10	human	human	JJ
cord-023443-pvz7dll9	544	11	monoclonal	monoclonal	JJ
cord-023443-pvz7dll9	544	12	antibody	antibody	NN
cord-023443-pvz7dll9	544	13	isolated	isolate	VBN
cord-023443-pvz7dll9	544	14	from	from	IN
cord-023443-pvz7dll9	544	15	sera	sera	NNP
cord-023443-pvz7dll9	544	16	of	of	IN
cord-023443-pvz7dll9	544	17	a	a	DT
cord-023443-pvz7dll9	544	18	patient	patient	NN
cord-023443-pvz7dll9	544	19	with	with	IN
cord-023443-pvz7dll9	544	20	Waldenstrom	Waldenstrom	NNP
cord-023443-pvz7dll9	544	21	macroglobulinaemia	macroglobulinaemia	NN
cord-023443-pvz7dll9	544	22	possess	possess	VBP
cord-023443-pvz7dll9	544	23	innate	innate	JJ
cord-023443-pvz7dll9	544	24	antibody	antibody	NN
cord-023443-pvz7dll9	544	25	characteristics	characteristic	NNS
cord-023443-pvz7dll9	544	26	and	and	CC
cord-023443-pvz7dll9	544	27	binds	bind	VBZ
cord-023443-pvz7dll9	544	28	to	to	IN
cord-023443-pvz7dll9	544	29	lactic	lactic	JJ
cord-023443-pvz7dll9	544	30	acid	acid	NN
cord-023443-pvz7dll9	544	31	bacteria	bacteria	NNS
cord-023443-pvz7dll9	544	32	.	.	.
cord-023443-pvz7dll9	545	1	According	accord	VBG
cord-023443-pvz7dll9	545	2	to	to	IN
cord-023443-pvz7dll9	545	3	the	the	DT
cord-023443-pvz7dll9	545	4	immune	immune	JJ
cord-023443-pvz7dll9	545	5	network	network	NN
cord-023443-pvz7dll9	545	6	model	model	NN
cord-023443-pvz7dll9	545	7	,	,	,
cord-023443-pvz7dll9	545	8	immunization	immunization	NN
cord-023443-pvz7dll9	545	9	with	with	IN
cord-023443-pvz7dll9	545	10	this	this	DT
cord-023443-pvz7dll9	545	11	bacteria	bacteria	NNS
cord-023443-pvz7dll9	545	12	could	could	MD
cord-023443-pvz7dll9	545	13	induce	induce	VB
cord-023443-pvz7dll9	545	14	the	the	DT
cord-023443-pvz7dll9	545	15	perturbations	perturbation	NNS
cord-023443-pvz7dll9	545	16	in	in	IN
cord-023443-pvz7dll9	545	17	immune	immune	JJ
cord-023443-pvz7dll9	545	18	system	system	NN
cord-023443-pvz7dll9	545	19	that	that	WDT
cord-023443-pvz7dll9	545	20	might	may	MD
cord-023443-pvz7dll9	545	21	result	result	VB
cord-023443-pvz7dll9	545	22	in	in	IN
cord-023443-pvz7dll9	545	23	production	production	NN
cord-023443-pvz7dll9	545	24	of	of	IN
cord-023443-pvz7dll9	545	25	anti	anti	JJ
cord-023443-pvz7dll9	545	26	-	-	JJ
cord-023443-pvz7dll9	545	27	Lactobacillus	lactobacillus	JJ
cord-023443-pvz7dll9	545	28	antibodies	antibody	NNS
cord-023443-pvz7dll9	545	29	,	,	,
cord-023443-pvz7dll9	545	30	human	human	JJ
cord-023443-pvz7dll9	545	31	monoclonal	monoclonal	JJ
cord-023443-pvz7dll9	545	32	antibody	antibody	NN
cord-023443-pvz7dll9	545	33	like	like	IN
cord-023443-pvz7dll9	545	34	(	(	-LRB-
cord-023443-pvz7dll9	545	35	Ab1	ab1	NN
cord-023443-pvz7dll9	545	36	)	)	-RRB-
cord-023443-pvz7dll9	545	37	and	and	CC
cord-023443-pvz7dll9	545	38	anti	anti	JJ
cord-023443-pvz7dll9	545	39	-	-	JJ
cord-023443-pvz7dll9	545	40	idiotypic	idiotypic	JJ
cord-023443-pvz7dll9	545	41	antibody	antibody	NN
cord-023443-pvz7dll9	545	42	(	(	-LRB-
cord-023443-pvz7dll9	545	43	Ab2	ab2	NN
cord-023443-pvz7dll9	545	44	)	)	-RRB-
cord-023443-pvz7dll9	545	45	.	.	.
cord-023443-pvz7dll9	546	1	In	in	IN
cord-023443-pvz7dll9	546	2	this	this	DT
cord-023443-pvz7dll9	546	3	study	study	NN
cord-023443-pvz7dll9	546	4	,	,	,
cord-023443-pvz7dll9	546	5	BALB	BALB	NNP
cord-023443-pvz7dll9	546	6	/	/	SYM
cord-023443-pvz7dll9	546	7	c	c	NN
cord-023443-pvz7dll9	546	8	mice	mouse	NNS
cord-023443-pvz7dll9	546	9	were	be	VBD
cord-023443-pvz7dll9	546	10	immunized	immunize	VBN
cord-023443-pvz7dll9	546	11	with	with	IN
cord-023443-pvz7dll9	546	12	two	two	CD
cord-023443-pvz7dll9	546	13	doses	dose	NNS
cord-023443-pvz7dll9	546	14	of	of	IN
cord-023443-pvz7dll9	546	15	bacteria	bacteria	NNS
cord-023443-pvz7dll9	546	16	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	546	17	acidophilus	acidophilus	NN
cord-023443-pvz7dll9	546	18	in	in	IN
cord-023443-pvz7dll9	546	19	complete	complete	JJ
cord-023443-pvz7dll9	546	20	and	and	CC
cord-023443-pvz7dll9	546	21	incomplete	incomplete	JJ
cord-023443-pvz7dll9	546	22	Freund	Freund	NNP
cord-023443-pvz7dll9	546	23	's	's	POS
cord-023443-pvz7dll9	546	24	adjuvant	adjuvant	NN
cord-023443-pvz7dll9	546	25	and	and	CC
cord-023443-pvz7dll9	546	26	phosphate	phosphate	NN
cord-023443-pvz7dll9	546	27	-	-	HYPH
cord-023443-pvz7dll9	546	28	buffered	buffer	VBN
cord-023443-pvz7dll9	546	29	saline	saline	NN
cord-023443-pvz7dll9	546	30	(	(	-LRB-
cord-023443-pvz7dll9	546	31	PBS	PBS	NNP
cord-023443-pvz7dll9	546	32	)	)	-RRB-
cord-023443-pvz7dll9	546	33	,	,	,
cord-023443-pvz7dll9	546	34	respectively	respectively	RB
cord-023443-pvz7dll9	546	35	.	.	.
cord-023443-pvz7dll9	547	1	Seven	seven	CD
cord-023443-pvz7dll9	547	2	days	day	NNS
cord-023443-pvz7dll9	547	3	after	after	IN
cord-023443-pvz7dll9	547	4	the	the	DT
cord-023443-pvz7dll9	547	5	last	last	JJ
cord-023443-pvz7dll9	547	6	immunization	immunization	NN
cord-023443-pvz7dll9	547	7	,	,	,
cord-023443-pvz7dll9	547	8	sera	sera	NNP
cord-023443-pvz7dll9	547	9	from	from	IN
cord-023443-pvz7dll9	547	10	immunized	immunize	VBN
cord-023443-pvz7dll9	547	11	mice	mouse	NNS
cord-023443-pvz7dll9	547	12	were	be	VBD
cord-023443-pvz7dll9	547	13	collected	collect	VBN
cord-023443-pvz7dll9	547	14	and	and	CC
cord-023443-pvz7dll9	547	15	the	the	DT
cord-023443-pvz7dll9	547	16	presence	presence	NN
cord-023443-pvz7dll9	547	17	of	of	IN
cord-023443-pvz7dll9	547	18	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	547	19	-	-	HYPH
cord-023443-pvz7dll9	547	20	specific	specific	JJ
cord-023443-pvz7dll9	547	21	Ab1	ab1	NN
cord-023443-pvz7dll9	547	22	and	and	CC
cord-023443-pvz7dll9	547	23	Ab2	ab2	NN
cord-023443-pvz7dll9	547	24	were	be	VBD
cord-023443-pvz7dll9	547	25	determined	determine	VBN
cord-023443-pvz7dll9	547	26	by	by	IN
cord-023443-pvz7dll9	547	27	ELISAs	elisa	NNS
cord-023443-pvz7dll9	547	28	.	.	.
cord-023443-pvz7dll9	548	1	In	in	IN
cord-023443-pvz7dll9	548	2	the	the	DT
cord-023443-pvz7dll9	548	3	sera	sera	NNP
cord-023443-pvz7dll9	548	4	of	of	IN
cord-023443-pvz7dll9	548	5	immunized	immunize	VBN
cord-023443-pvz7dll9	548	6	mice	mouse	NNS
cord-023443-pvz7dll9	548	7	,	,	,
cord-023443-pvz7dll9	548	8	antibodies	antibody	NNS
cord-023443-pvz7dll9	548	9	specific	specific	JJ
cord-023443-pvz7dll9	548	10	to	to	IN
cord-023443-pvz7dll9	548	11	bacteria	bacteria	NNS
cord-023443-pvz7dll9	548	12	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	548	13	acidophilus	acidophilus	NN
cord-023443-pvz7dll9	548	14	were	be	VBD
cord-023443-pvz7dll9	548	15	shown	show	VBN
cord-023443-pvz7dll9	548	16	.	.	.
cord-023443-pvz7dll9	549	1	The	the	DT
cord-023443-pvz7dll9	549	2	concentration	concentration	NN
cord-023443-pvz7dll9	549	3	of	of	IN
cord-023443-pvz7dll9	549	4	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	549	5	-	-	HYPH
cord-023443-pvz7dll9	549	6	specific	specific	JJ
cord-023443-pvz7dll9	549	7	antibodies	antibody	NNS
cord-023443-pvz7dll9	549	8	was	be	VBD
cord-023443-pvz7dll9	549	9	higher	high	JJR
cord-023443-pvz7dll9	549	10	in	in	IN
cord-023443-pvz7dll9	549	11	the	the	DT
cord-023443-pvz7dll9	549	12	sera	sera	NNP
cord-023443-pvz7dll9	549	13	of	of	IN
cord-023443-pvz7dll9	549	14	hyperimmunized	hyperimmunize	VBN
cord-023443-pvz7dll9	549	15	mice	mouse	NNS
cord-023443-pvz7dll9	549	16	(	(	-LRB-
cord-023443-pvz7dll9	549	17	mice	mouse	NNS
cord-023443-pvz7dll9	549	18	immunized	immunize	VBN
cord-023443-pvz7dll9	549	19	with	with	IN
cord-023443-pvz7dll9	549	20	1	1	CD
cord-023443-pvz7dll9	549	21	mg	mg	NNP
cord-023443-pvz7dll9	549	22	of	of	IN
cord-023443-pvz7dll9	549	23	IgM	IgM	NNP
cord-023443-pvz7dll9	549	24	DJ	DJ	NNP
cord-023443-pvz7dll9	549	25	)	)	-RRB-
cord-023443-pvz7dll9	549	26	than	than	IN
cord-023443-pvz7dll9	549	27	in	in	IN
cord-023443-pvz7dll9	549	28	sera	sera	NNP
cord-023443-pvz7dll9	549	29	of	of	IN
cord-023443-pvz7dll9	549	30	mice	mouse	NNS
cord-023443-pvz7dll9	549	31	immunized	immunize	VBN
cord-023443-pvz7dll9	549	32	with	with	IN
cord-023443-pvz7dll9	549	33	100	100	CD
cord-023443-pvz7dll9	549	34	times	time	NNS
cord-023443-pvz7dll9	549	35	lower	low	JJR
cord-023443-pvz7dll9	549	36	doses	dose	NNS
cord-023443-pvz7dll9	549	37	of	of	IN
cord-023443-pvz7dll9	549	38	immunogen	immunogen	NN
cord-023443-pvz7dll9	549	39	(	(	-LRB-
cord-023443-pvz7dll9	549	40	0.01	0.01	CD
cord-023443-pvz7dll9	549	41	mg	mg	NN
cord-023443-pvz7dll9	549	42	per	per	IN
cord-023443-pvz7dll9	549	43	doses	dose	NNS
cord-023443-pvz7dll9	549	44	)	)	-RRB-
cord-023443-pvz7dll9	549	45	.	.	.
cord-023443-pvz7dll9	550	1	Moreover	moreover	RB
cord-023443-pvz7dll9	550	2	,	,	,
cord-023443-pvz7dll9	550	3	Ab1	ab1	NN
cord-023443-pvz7dll9	550	4	and	and	CC
cord-023443-pvz7dll9	550	5	Ab2	ab2	NN
cord-023443-pvz7dll9	550	6	antibodies	antibody	NNS
cord-023443-pvz7dll9	550	7	were	be	VBD
cord-023443-pvz7dll9	550	8	detected	detect	VBN
cord-023443-pvz7dll9	550	9	in	in	IN
cord-023443-pvz7dll9	550	10	the	the	DT
cord-023443-pvz7dll9	550	11	sera	sera	NNP
cord-023443-pvz7dll9	550	12	of	of	IN
cord-023443-pvz7dll9	550	13	Lactobacillus	Lactobacillus	NNP
cord-023443-pvz7dll9	550	14	-	-	HYPH
cord-023443-pvz7dll9	550	15	hyperimmunized	hyperimmunize	VBN
cord-023443-pvz7dll9	550	16	mice	mouse	NNS
cord-023443-pvz7dll9	550	17	.	.	.
cord-023443-pvz7dll9	551	1	In	in	IN
cord-023443-pvz7dll9	551	2	this	this	DT
cord-023443-pvz7dll9	551	3	study	study	NN
cord-023443-pvz7dll9	551	4	,	,	,
cord-023443-pvz7dll9	551	5	we	-PRON-	PRP
cord-023443-pvz7dll9	551	6	have	have	VBP
cord-023443-pvz7dll9	551	7	shown	show	VBN
cord-023443-pvz7dll9	551	8	the	the	DT
cord-023443-pvz7dll9	551	9	idiotypic	idiotypic	NNP
cord-023443-pvz7dll9	551	10	network	network	NN
cord-023443-pvz7dll9	551	11	interactions	interaction	NNS
cord-023443-pvz7dll9	551	12	in	in	IN
cord-023443-pvz7dll9	551	13	mice	mouse	NNS
cord-023443-pvz7dll9	551	14	immunized	immunize	VBN
cord-023443-pvz7dll9	551	15	with	with	IN
cord-023443-pvz7dll9	551	16	bacteria	bacteria	NNS
cord-023443-pvz7dll9	551	17	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	551	18	acidophilus	acidophilus	NN
cord-023443-pvz7dll9	551	19	.	.	.
cord-023443-pvz7dll9	552	1	The	the	DT
cord-023443-pvz7dll9	552	2	normal	normal	JJ
cord-023443-pvz7dll9	552	3	gastrointestinal	gastrointestinal	JJ
cord-023443-pvz7dll9	552	4	flora	flora	NNS
cord-023443-pvz7dll9	552	5	is	be	VBZ
cord-023443-pvz7dll9	552	6	crucial	crucial	JJ
cord-023443-pvz7dll9	552	7	for	for	IN
cord-023443-pvz7dll9	552	8	the	the	DT
cord-023443-pvz7dll9	552	9	maturation	maturation	NN
cord-023443-pvz7dll9	552	10	of	of	IN
cord-023443-pvz7dll9	552	11	the	the	DT
cord-023443-pvz7dll9	552	12	acquired	acquire	VBN
cord-023443-pvz7dll9	552	13	immunity	immunity	NN
cord-023443-pvz7dll9	552	14	via	via	IN
cord-023443-pvz7dll9	552	15	effects	effect	NNS
cord-023443-pvz7dll9	552	16	on	on	IN
cord-023443-pvz7dll9	552	17	antigenpresenting	antigenpresente	VBG
cord-023443-pvz7dll9	552	18	cells	cell	NNS
cord-023443-pvz7dll9	552	19	(	(	-LRB-
cord-023443-pvz7dll9	552	20	APCs	apc	NNS
cord-023443-pvz7dll9	552	21	)	)	-RRB-
cord-023443-pvz7dll9	552	22	.	.	.
cord-023443-pvz7dll9	553	1	Here	here	RB
cord-023443-pvz7dll9	553	2	,	,	,
cord-023443-pvz7dll9	553	3	we	-PRON-	PRP
cord-023443-pvz7dll9	553	4	have	have	VBP
cord-023443-pvz7dll9	553	5	investigated	investigate	VBN
cord-023443-pvz7dll9	553	6	how	how	WRB
cord-023443-pvz7dll9	553	7	two	two	CD
cord-023443-pvz7dll9	553	8	types	type	NNS
cord-023443-pvz7dll9	553	9	of	of	IN
cord-023443-pvz7dll9	553	10	APCs	apc	NNS
cord-023443-pvz7dll9	553	11	,	,	,
cord-023443-pvz7dll9	553	12	monocytes	monocyte	NNS
cord-023443-pvz7dll9	553	13	and	and	CC
cord-023443-pvz7dll9	553	14	dendritic	dendritic	JJ
cord-023443-pvz7dll9	553	15	cells	cell	NNS
cord-023443-pvz7dll9	553	16	(	(	-LRB-
cord-023443-pvz7dll9	553	17	DCs	DCs	NNP
cord-023443-pvz7dll9	553	18	)	)	-RRB-
cord-023443-pvz7dll9	553	19	,	,	,
cord-023443-pvz7dll9	553	20	react	react	VBP
cord-023443-pvz7dll9	553	21	to	to	IN
cord-023443-pvz7dll9	553	22	different	different	JJ
cord-023443-pvz7dll9	553	23	bacterial	bacterial	JJ
cord-023443-pvz7dll9	553	24	strains	strain	NNS
cord-023443-pvz7dll9	553	25	typical	typical	JJ
cord-023443-pvz7dll9	553	26	of	of	IN
cord-023443-pvz7dll9	553	27	the	the	DT
cord-023443-pvz7dll9	553	28	commensal	commensal	JJ
cord-023443-pvz7dll9	553	29	intestinal	intestinal	JJ
cord-023443-pvz7dll9	553	30	flora	flora	NNS
cord-023443-pvz7dll9	553	31	.	.	.
cord-023443-pvz7dll9	554	1	Purified	purify	VBN
cord-023443-pvz7dll9	554	2	monocytes	monocyte	NNS
cord-023443-pvz7dll9	554	3	and	and	CC
cord-023443-pvz7dll9	554	4	monocyte	monocyte	NN
cord-023443-pvz7dll9	554	5	-	-	HYPH
cord-023443-pvz7dll9	554	6	derived	derive	VBN
cord-023443-pvz7dll9	554	7	DCs	dc	NNS
cord-023443-pvz7dll9	554	8	were	be	VBD
cord-023443-pvz7dll9	554	9	stimulated	stimulate	VBN
cord-023443-pvz7dll9	554	10	with	with	IN
cord-023443-pvz7dll9	554	11	UV	uv	NN
cord-023443-pvz7dll9	554	12	-	-	HYPH
cord-023443-pvz7dll9	554	13	inactivated	inactivate	VBN
cord-023443-pvz7dll9	554	14	gram	gram	NN
cord-023443-pvz7dll9	554	15	-	-	HYPH
cord-023443-pvz7dll9	554	16	positive	positive	JJ
cord-023443-pvz7dll9	554	17	(	(	-LRB-
cord-023443-pvz7dll9	554	18	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	554	19	plantarum	plantarum	NNS
cord-023443-pvz7dll9	554	20	and	and	CC
cord-023443-pvz7dll9	554	21	Bifidobacterium	Bifidobacterium	NNP
cord-023443-pvz7dll9	554	22	adolescentis	adolescentis	NNP
cord-023443-pvz7dll9	554	23	)	)	-RRB-
cord-023443-pvz7dll9	554	24	and	and	CC
cord-023443-pvz7dll9	554	25	gram	gram	NN
cord-023443-pvz7dll9	554	26	-	-	HYPH
cord-023443-pvz7dll9	554	27	negative	negative	JJ
cord-023443-pvz7dll9	554	28	(	(	-LRB-
cord-023443-pvz7dll9	554	29	Escherichia	escherichia	NN
cord-023443-pvz7dll9	554	30	coli	coli	NNS
cord-023443-pvz7dll9	554	31	and	and	CC
cord-023443-pvz7dll9	554	32	Veillonella	Veillonella	NNP
cord-023443-pvz7dll9	554	33	parvula	parvula	NN
cord-023443-pvz7dll9	554	34	)	)	-RRB-
cord-023443-pvz7dll9	554	35	bacterial	bacterial	JJ
cord-023443-pvz7dll9	554	36	strains	strain	NNS
cord-023443-pvz7dll9	554	37	.	.	.
cord-023443-pvz7dll9	555	1	Monocytes	monocyte	NNS
cord-023443-pvz7dll9	555	2	produced	produce	VBD
cord-023443-pvz7dll9	555	3	higher	high	JJR
cord-023443-pvz7dll9	555	4	levels	level	NNS
cord-023443-pvz7dll9	555	5	of	of	IN
cord-023443-pvz7dll9	555	6	IL-12p70	IL-12p70	NNP
cord-023443-pvz7dll9	555	7	and	and	CC
cord-023443-pvz7dll9	555	8	TNF	TNF	NNP
cord-023443-pvz7dll9	555	9	,	,	,
cord-023443-pvz7dll9	555	10	as	as	IN
cord-023443-pvz7dll9	555	11	detected	detect	VBN
cord-023443-pvz7dll9	555	12	by	by	IN
cord-023443-pvz7dll9	555	13	ELISA	ELISA	NNP
cord-023443-pvz7dll9	555	14	,	,	,
cord-023443-pvz7dll9	555	15	in	in	IN
cord-023443-pvz7dll9	555	16	response	response	NN
cord-023443-pvz7dll9	555	17	to	to	IN
cord-023443-pvz7dll9	555	18	L.	L.	NNP
cord-023443-pvz7dll9	555	19	plantarum	plantarum	NNS
cord-023443-pvz7dll9	555	20	than	than	IN
cord-023443-pvz7dll9	555	21	to	to	IN
cord-023443-pvz7dll9	555	22	E.	E.	NNP
cord-023443-pvz7dll9	555	23	coli	coli	NNS
cord-023443-pvz7dll9	555	24	and	and	CC
cord-023443-pvz7dll9	555	25	V.	V.	NNP
cord-023443-pvz7dll9	555	26	parvula	parvula	NNP
cord-023443-pvz7dll9	555	27	.	.	.
cord-023443-pvz7dll9	556	1	In	in	IN
cord-023443-pvz7dll9	556	2	contrast	contrast	NN
cord-023443-pvz7dll9	556	3	,	,	,
cord-023443-pvz7dll9	556	4	DCs	DCs	NNP
cord-023443-pvz7dll9	556	5	secreted	secrete	VBD
cord-023443-pvz7dll9	556	6	high	high	JJ
cord-023443-pvz7dll9	556	7	amounts	amount	NNS
cord-023443-pvz7dll9	556	8	of	of	IN
cord-023443-pvz7dll9	556	9	IL-12p70	IL-12p70	NNP
cord-023443-pvz7dll9	556	10	,	,	,
cord-023443-pvz7dll9	556	11	TNF	TNF	NNP
cord-023443-pvz7dll9	556	12	,	,	,
cord-023443-pvz7dll9	556	13	IL-6	IL-6	NNP
cord-023443-pvz7dll9	556	14	and	and	CC
cord-023443-pvz7dll9	556	15	IL-10	IL-10	NNP
cord-023443-pvz7dll9	556	16	in	in	IN
cord-023443-pvz7dll9	556	17	response	response	NN
cord-023443-pvz7dll9	556	18	to	to	IN
cord-023443-pvz7dll9	556	19	E.	E.	NNP
cord-023443-pvz7dll9	556	20	coli	coli	NNS
cord-023443-pvz7dll9	556	21	and	and	CC
cord-023443-pvz7dll9	556	22	V.	V.	NNP
cord-023443-pvz7dll9	556	23	parvula	parvula	NN
cord-023443-pvz7dll9	556	24	but	but	CC
cord-023443-pvz7dll9	556	25	were	be	VBD
cord-023443-pvz7dll9	556	26	practically	practically	RB
cord-023443-pvz7dll9	556	27	unresponsive	unresponsive	JJ
cord-023443-pvz7dll9	556	28	to	to	IN
cord-023443-pvz7dll9	556	29	L.	L.	NNP
cord-023443-pvz7dll9	556	30	plantarum	plantarum	NNS
cord-023443-pvz7dll9	556	31	and	and	CC
cord-023443-pvz7dll9	556	32	B.	B.	NNP
cord-023443-pvz7dll9	556	33	adolescentis	adolescentis	NNP
cord-023443-pvz7dll9	556	34	.	.	.
cord-023443-pvz7dll9	557	1	The	the	DT
cord-023443-pvz7dll9	557	2	lack	lack	NN
cord-023443-pvz7dll9	557	3	of	of	IN
cord-023443-pvz7dll9	557	4	response	response	NN
cord-023443-pvz7dll9	557	5	to	to	IN
cord-023443-pvz7dll9	557	6	the	the	DT
cord-023443-pvz7dll9	557	7	gram	gram	NN
cord-023443-pvz7dll9	557	8	-	-	HYPH
cord-023443-pvz7dll9	557	9	positive	positive	JJ
cord-023443-pvz7dll9	557	10	strains	strain	NNS
cord-023443-pvz7dll9	557	11	correlated	correlate	VBN
cord-023443-pvz7dll9	557	12	with	with	IN
cord-023443-pvz7dll9	557	13	a	a	DT
cord-023443-pvz7dll9	557	14	lower	low	JJR
cord-023443-pvz7dll9	557	15	surface	surface	NN
cord-023443-pvz7dll9	557	16	expression	expression	NN
cord-023443-pvz7dll9	557	17	of	of	IN
cord-023443-pvz7dll9	557	18	Toll	Toll	NNP
cord-023443-pvz7dll9	557	19	-	-	HYPH
cord-023443-pvz7dll9	557	20	like	like	JJ
cord-023443-pvz7dll9	557	21	reseptor	reseptor	NNP
cord-023443-pvz7dll9	557	22	2	2	CD
cord-023443-pvz7dll9	557	23	(	(	-LRB-
cord-023443-pvz7dll9	557	24	TLR2	TLR2	NNP
cord-023443-pvz7dll9	557	25	)	)	-RRB-
cord-023443-pvz7dll9	557	26	on	on	IN
cord-023443-pvz7dll9	557	27	DCs	dc	NNS
cord-023443-pvz7dll9	557	28	compared	compare	VBN
cord-023443-pvz7dll9	557	29	to	to	IN
cord-023443-pvz7dll9	557	30	monocytes	monocyte	NNS
cord-023443-pvz7dll9	557	31	.	.	.
cord-023443-pvz7dll9	558	1	The	the	DT
cord-023443-pvz7dll9	558	2	surface	surface	NN
cord-023443-pvz7dll9	558	3	expression	expression	NN
cord-023443-pvz7dll9	558	4	of	of	IN
cord-023443-pvz7dll9	558	5	TLR4	TLR4	NNP
cord-023443-pvz7dll9	558	6	on	on	IN
cord-023443-pvz7dll9	558	7	DCs	dc	NNS
cord-023443-pvz7dll9	558	8	was	be	VBD
cord-023443-pvz7dll9	558	9	undetectable	undetectable	JJ
cord-023443-pvz7dll9	558	10	when	when	WRB
cord-023443-pvz7dll9	558	11	analysed	analyse	VBN
cord-023443-pvz7dll9	558	12	by	by	IN
cord-023443-pvz7dll9	558	13	flow	flow	NN
cord-023443-pvz7dll9	558	14	cytometry	cytometry	NN
cord-023443-pvz7dll9	558	15	,	,	,
cord-023443-pvz7dll9	558	16	but	but	CC
cord-023443-pvz7dll9	558	17	blocking	block	VBG
cord-023443-pvz7dll9	558	18	this	this	DT
cord-023443-pvz7dll9	558	19	receptor	receptor	NN
cord-023443-pvz7dll9	558	20	decreased	decrease	VBD
cord-023443-pvz7dll9	558	21	the	the	DT
cord-023443-pvz7dll9	558	22	TNF	TNF	NNP
cord-023443-pvz7dll9	558	23	production	production	NN
cord-023443-pvz7dll9	558	24	in	in	IN
cord-023443-pvz7dll9	558	25	response	response	NN
cord-023443-pvz7dll9	558	26	to	to	IN
cord-023443-pvz7dll9	558	27	V.	V.	NNP
cord-023443-pvz7dll9	558	28	parvula	parvula	NNP
cord-023443-pvz7dll9	558	29	,	,	,
cord-023443-pvz7dll9	558	30	indicating	indicate	VBG
cord-023443-pvz7dll9	558	31	that	that	IN
cord-023443-pvz7dll9	558	32	low	low	JJ
cord-023443-pvz7dll9	558	33	TLR4	tlr4	CD
cord-023443-pvz7dll9	558	34	expression	expression	NN
cord-023443-pvz7dll9	558	35	on	on	IN
cord-023443-pvz7dll9	558	36	DCs	DCs	NNP
cord-023443-pvz7dll9	558	37	is	be	VBZ
cord-023443-pvz7dll9	558	38	sufficient	sufficient	JJ
cord-023443-pvz7dll9	558	39	to	to	TO
cord-023443-pvz7dll9	558	40	mount	mount	VB
cord-023443-pvz7dll9	558	41	an	an	DT
cord-023443-pvz7dll9	558	42	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	558	43	response	response	NN
cord-023443-pvz7dll9	558	44	to	to	IN
cord-023443-pvz7dll9	558	45	gram	gram	JJ
cord-023443-pvz7dll9	558	46	-	-	HYPH
cord-023443-pvz7dll9	558	47	negative	negative	JJ
cord-023443-pvz7dll9	558	48	bacteria	bacteria	NNS
cord-023443-pvz7dll9	558	49	.	.	.
cord-023443-pvz7dll9	559	1	IFN	IFN	NNP
cord-023443-pvz7dll9	559	2	-	-	HYPH
cord-023443-pvz7dll9	559	3	g	g	NNP
cord-023443-pvz7dll9	559	4	increased	increase	VBD
cord-023443-pvz7dll9	559	5	the	the	DT
cord-023443-pvz7dll9	559	6	expression	expression	NN
cord-023443-pvz7dll9	559	7	of	of	IN
cord-023443-pvz7dll9	559	8	TLR4	TLR4	NNP
cord-023443-pvz7dll9	559	9	on	on	IN
cord-023443-pvz7dll9	559	10	DCs	dc	NNS
cord-023443-pvz7dll9	559	11	and	and	CC
cord-023443-pvz7dll9	559	12	also	also	RB
cord-023443-pvz7dll9	559	13	potentiated	potentiate	VBD
cord-023443-pvz7dll9	559	14	the	the	DT
cord-023443-pvz7dll9	559	15	cytokine	cytokine	NN
cord-023443-pvz7dll9	559	16	response	response	NN
cord-023443-pvz7dll9	559	17	to	to	IN
cord-023443-pvz7dll9	559	18	gram	gram	JJ
cord-023443-pvz7dll9	559	19	-	-	HYPH
cord-023443-pvz7dll9	559	20	negative	negative	JJ
cord-023443-pvz7dll9	559	21	bacteria	bacteria	NNS
cord-023443-pvz7dll9	559	22	.	.	.
cord-023443-pvz7dll9	560	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	560	2	results	result	NNS
cord-023443-pvz7dll9	560	3	indicate	indicate	VBP
cord-023443-pvz7dll9	560	4	that	that	IN
cord-023443-pvz7dll9	560	5	,	,	,
cord-023443-pvz7dll9	560	6	when	when	WRB
cord-023443-pvz7dll9	560	7	monocytes	monocyte	NNS
cord-023443-pvz7dll9	560	8	differentiate	differentiate	VBP
cord-023443-pvz7dll9	560	9	into	into	IN
cord-023443-pvz7dll9	560	10	DCs	dc	NNS
cord-023443-pvz7dll9	560	11	,	,	,
cord-023443-pvz7dll9	560	12	their	-PRON-	PRP$
cord-023443-pvz7dll9	560	13	ability	ability	NN
cord-023443-pvz7dll9	560	14	to	to	TO
cord-023443-pvz7dll9	560	15	respond	respond	VB
cord-023443-pvz7dll9	560	16	to	to	IN
cord-023443-pvz7dll9	560	17	different	different	JJ
cord-023443-pvz7dll9	560	18	commensal	commensal	JJ
cord-023443-pvz7dll9	560	19	bacteria	bacteria	NNS
cord-023443-pvz7dll9	560	20	dramatically	dramatically	RB
cord-023443-pvz7dll9	560	21	changes	change	NNS
cord-023443-pvz7dll9	560	22	,	,	,
cord-023443-pvz7dll9	560	23	thereby	thereby	RB
cord-023443-pvz7dll9	560	24	becoming	become	VBG
cord-023443-pvz7dll9	560	25	unresponsive	unresponsive	JJ
cord-023443-pvz7dll9	560	26	to	to	IN
cord-023443-pvz7dll9	560	27	probiotic	probiotic	JJ
cord-023443-pvz7dll9	560	28	gram	gram	NN
cord-023443-pvz7dll9	560	29	-	-	HYPH
cord-023443-pvz7dll9	560	30	positive	positive	JJ
cord-023443-pvz7dll9	560	31	bacteria	bacteria	NNS
cord-023443-pvz7dll9	560	32	.	.	.
cord-023443-pvz7dll9	561	1	These	these	DT
cord-023443-pvz7dll9	561	2	results	result	NNS
cord-023443-pvz7dll9	561	3	may	may	MD
cord-023443-pvz7dll9	561	4	have	have	VB
cord-023443-pvz7dll9	561	5	important	important	JJ
cord-023443-pvz7dll9	561	6	implications	implication	NNS
cord-023443-pvz7dll9	561	7	for	for	IN
cord-023443-pvz7dll9	561	8	the	the	DT
cord-023443-pvz7dll9	561	9	capacity	capacity	NN
cord-023443-pvz7dll9	561	10	of	of	IN
cord-023443-pvz7dll9	561	11	different	different	JJ
cord-023443-pvz7dll9	561	12	groups	group	NNS
cord-023443-pvz7dll9	561	13	of	of	IN
cord-023443-pvz7dll9	561	14	commensal	commensal	JJ
cord-023443-pvz7dll9	561	15	bacteria	bacteria	NNS
cord-023443-pvz7dll9	561	16	to	to	TO
cord-023443-pvz7dll9	561	17	regulate	regulate	VB
cord-023443-pvz7dll9	561	18	mucosal	mucosal	JJ
cord-023443-pvz7dll9	561	19	and	and	CC
cord-023443-pvz7dll9	561	20	systemic	systemic	JJ
cord-023443-pvz7dll9	561	21	immunity	immunity	NN
cord-023443-pvz7dll9	561	22	.	.	.
cord-023443-pvz7dll9	562	1	Probiotic	probiotic	JJ
cord-023443-pvz7dll9	562	2	bacteria	bacteria	NNS
cord-023443-pvz7dll9	562	3	,	,	,
cord-023443-pvz7dll9	562	4	e.g.	e.g.	RB
cord-023443-pvz7dll9	562	5	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	562	6	spp	spp	NNS
cord-023443-pvz7dll9	562	7	.	.	.
cord-023443-pvz7dll9	562	8	,	,	,
cord-023443-pvz7dll9	562	9	may	may	MD
cord-023443-pvz7dll9	562	10	improve	improve	VB
cord-023443-pvz7dll9	562	11	diseases	disease	NNS
cord-023443-pvz7dll9	562	12	such	such	JJ
cord-023443-pvz7dll9	562	13	as	as	IN
cord-023443-pvz7dll9	562	14	chronic	chronic	JJ
cord-023443-pvz7dll9	562	15	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	562	16	bowel	bowel	NN
cord-023443-pvz7dll9	562	17	disease	disease	NN
cord-023443-pvz7dll9	562	18	.	.	.
cord-023443-pvz7dll9	563	1	We	-PRON-	PRP
cord-023443-pvz7dll9	563	2	examined	examine	VBD
cord-023443-pvz7dll9	563	3	cytokine	cytokine	JJ
cord-023443-pvz7dll9	563	4	production	production	NN
cord-023443-pvz7dll9	563	5	and	and	CC
cord-023443-pvz7dll9	563	6	phenotypic	phenotypic	JJ
cord-023443-pvz7dll9	563	7	change	change	NN
cord-023443-pvz7dll9	563	8	after	after	IN
cord-023443-pvz7dll9	563	9	in	in	IN
cord-023443-pvz7dll9	563	10	vitro	vitro	FW
cord-023443-pvz7dll9	563	11	stimulation	stimulation	NN
cord-023443-pvz7dll9	563	12	of	of	IN
cord-023443-pvz7dll9	563	13	T	t	NN
cord-023443-pvz7dll9	563	14	cells	cell	NNS
cord-023443-pvz7dll9	563	15	from	from	IN
cord-023443-pvz7dll9	563	16	healthy	healthy	JJ
cord-023443-pvz7dll9	563	17	volunteers	volunteer	NNS
cord-023443-pvz7dll9	563	18	using	use	VBG
cord-023443-pvz7dll9	563	19	different	different	JJ
cord-023443-pvz7dll9	563	20	probiotic	probiotic	JJ
cord-023443-pvz7dll9	563	21	strains	strain	NNS
cord-023443-pvz7dll9	563	22	.	.	.
cord-023443-pvz7dll9	564	1	Methods	method	NNS
cord-023443-pvz7dll9	564	2	:	:	:
cord-023443-pvz7dll9	564	3	T	t	NN
cord-023443-pvz7dll9	564	4	cells	cell	NNS
cord-023443-pvz7dll9	564	5	were	be	VBD
cord-023443-pvz7dll9	564	6	cultured	culture	VBN
cord-023443-pvz7dll9	564	7	from	from	IN
cord-023443-pvz7dll9	564	8	colonic	colonic	JJ
cord-023443-pvz7dll9	564	9	biopsies	biopsy	NNS
cord-023443-pvz7dll9	564	10	from	from	IN
cord-023443-pvz7dll9	564	11	eight	eight	CD
cord-023443-pvz7dll9	564	12	healthy	healthy	JJ
cord-023443-pvz7dll9	564	13	volunteers	volunteer	NNS
cord-023443-pvz7dll9	564	14	(	(	-LRB-
cord-023443-pvz7dll9	564	15	Agnholt	Agnholt	NNP
cord-023443-pvz7dll9	564	16	and	and	CC
cord-023443-pvz7dll9	564	17	Kaltoft	Kaltoft	NNP
cord-023443-pvz7dll9	564	18	,	,	,
cord-023443-pvz7dll9	564	19	Exp	Exp	NNP
cord-023443-pvz7dll9	564	20	Clin	Clin	NNP
cord-023443-pvz7dll9	564	21	Immunogenet	Immunogenet	NNP
cord-023443-pvz7dll9	564	22	2001	2001	CD
cord-023443-pvz7dll9	564	23	;	;	:
cord-023443-pvz7dll9	564	24	18:213	18:213	CD
cord-023443-pvz7dll9	564	25	-	-	SYM
cord-023443-pvz7dll9	564	26	25	25	CD
cord-023443-pvz7dll9	564	27	)	)	-RRB-
cord-023443-pvz7dll9	564	28	,	,	,
cord-023443-pvz7dll9	564	29	and	and	CC
cord-023443-pvz7dll9	564	30	dendritic	dendritic	JJ
cord-023443-pvz7dll9	564	31	cells	cell	NNS
cord-023443-pvz7dll9	564	32	were	be	VBD
cord-023443-pvz7dll9	564	33	matured	mature	VBN
cord-023443-pvz7dll9	564	34	from	from	IN
cord-023443-pvz7dll9	564	35	their	-PRON-	PRP$
cord-023443-pvz7dll9	564	36	peripheral	peripheral	JJ
cord-023443-pvz7dll9	564	37	blood	blood	NN
cord-023443-pvz7dll9	564	38	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	564	39	cells	cell	NNS
cord-023443-pvz7dll9	564	40	.	.	.
cord-023443-pvz7dll9	565	1	T	t	NN
cord-023443-pvz7dll9	565	2	-	-	HYPH
cord-023443-pvz7dll9	565	3	cell	cell	NN
cord-023443-pvz7dll9	565	4	cultures	culture	NNS
cord-023443-pvz7dll9	565	5	were	be	VBD
cord-023443-pvz7dll9	565	6	stimulated	stimulate	VBN
cord-023443-pvz7dll9	565	7	with	with	IN
cord-023443-pvz7dll9	565	8	autologous	autologous	JJ
cord-023443-pvz7dll9	565	9	bacterial	bacterial	JJ
cord-023443-pvz7dll9	565	10	sonicate	sonicate	NN
cord-023443-pvz7dll9	565	11	or	or	CC
cord-023443-pvz7dll9	565	12	strains	strain	NNS
cord-023443-pvz7dll9	565	13	of	of	IN
cord-023443-pvz7dll9	565	14	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	565	15	spp	spp	NNS
cord-023443-pvz7dll9	565	16	.	.	.
cord-023443-pvz7dll9	566	1	,	,	,
cord-023443-pvz7dll9	566	2	with	with	IN
cord-023443-pvz7dll9	566	3	and	and	CC
cord-023443-pvz7dll9	566	4	without	without	IN
cord-023443-pvz7dll9	566	5	the	the	DT
cord-023443-pvz7dll9	566	6	addition	addition	NN
cord-023443-pvz7dll9	566	7	of	of	IN
cord-023443-pvz7dll9	566	8	dendritic	dendritic	JJ
cord-023443-pvz7dll9	566	9	cells	cell	NNS
cord-023443-pvz7dll9	566	10	.	.	.
cord-023443-pvz7dll9	567	1	Cytokine	cytokine	NN
cord-023443-pvz7dll9	567	2	levels	level	NNS
cord-023443-pvz7dll9	567	3	(	(	-LRB-
cord-023443-pvz7dll9	567	4	TNF	TNF	NNP
cord-023443-pvz7dll9	567	5	-	-	HYPH
cord-023443-pvz7dll9	567	6	a	a	NNP
cord-023443-pvz7dll9	567	7	,	,	,
cord-023443-pvz7dll9	567	8	IFN	IFN	NNP
cord-023443-pvz7dll9	567	9	-	-	HYPH
cord-023443-pvz7dll9	567	10	g	g	NNP
cord-023443-pvz7dll9	567	11	,	,	,
cord-023443-pvz7dll9	567	12	IL-10	IL-10	NNP
cord-023443-pvz7dll9	567	13	and	and	CC
cord-023443-pvz7dll9	567	14	GM	GM	NNP
cord-023443-pvz7dll9	567	15	-	-	HYPH
cord-023443-pvz7dll9	567	16	CSF	CSF	NNP
cord-023443-pvz7dll9	567	17	)	)	-RRB-
cord-023443-pvz7dll9	567	18	and	and	CC
cord-023443-pvz7dll9	567	19	phenotype	phenotype	NN
cord-023443-pvz7dll9	567	20	(	(	-LRB-
cord-023443-pvz7dll9	567	21	CD3	CD3	NNP
cord-023443-pvz7dll9	567	22	,	,	,
cord-023443-pvz7dll9	567	23	CD4	CD4	NNP
cord-023443-pvz7dll9	567	24	,	,	,
cord-023443-pvz7dll9	567	25	CD25	CD25	NNP
cord-023443-pvz7dll9	567	26	and	and	CC
cord-023443-pvz7dll9	567	27	CD69	CD69	NNP
cord-023443-pvz7dll9	567	28	)	)	-RRB-
cord-023443-pvz7dll9	567	29	were	be	VBD
cord-023443-pvz7dll9	567	30	measured	measure	VBN
cord-023443-pvz7dll9	567	31	on	on	IN
cord-023443-pvz7dll9	567	32	day	day	NN
cord-023443-pvz7dll9	567	33	4	4	CD
cord-023443-pvz7dll9	567	34	.	.	.
cord-023443-pvz7dll9	568	1	Results	result	NNS
cord-023443-pvz7dll9	568	2	:	:	:
cord-023443-pvz7dll9	569	1	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	569	2	spp	spp	NNS
cord-023443-pvz7dll9	569	3	.	.	.
cord-023443-pvz7dll9	570	1	induced	induce	VBN
cord-023443-pvz7dll9	570	2	higher	high	JJR
cord-023443-pvz7dll9	570	3	productions	production	NNS
cord-023443-pvz7dll9	570	4	of	of	IN
cord-023443-pvz7dll9	570	5	TNF	TNF	NNP
cord-023443-pvz7dll9	570	6	-	-	:
cord-023443-pvz7dll9	570	7	a	a	NNP
cord-023443-pvz7dll9	570	8	and	and	CC
cord-023443-pvz7dll9	570	9	IL-10	IL-10	NNP
cord-023443-pvz7dll9	570	10	than	than	IN
cord-023443-pvz7dll9	570	11	did	do	VBD
cord-023443-pvz7dll9	570	12	autologous	autologous	JJ
cord-023443-pvz7dll9	570	13	bacteria	bacteria	NNS
cord-023443-pvz7dll9	570	14	.	.	.
cord-023443-pvz7dll9	571	1	In	in	IN
cord-023443-pvz7dll9	571	2	presence	presence	NN
cord-023443-pvz7dll9	571	3	of	of	IN
cord-023443-pvz7dll9	571	4	dendritic	dendritic	JJ
cord-023443-pvz7dll9	571	5	cells	cell	NNS
cord-023443-pvz7dll9	571	6	,	,	,
cord-023443-pvz7dll9	571	7	the	the	DT
cord-023443-pvz7dll9	571	8	production	production	NN
cord-023443-pvz7dll9	571	9	of	of	IN
cord-023443-pvz7dll9	571	10	all	all	DT
cord-023443-pvz7dll9	571	11	cytokines	cytokine	NNS
cord-023443-pvz7dll9	571	12	increased	increase	VBD
cord-023443-pvz7dll9	571	13	.	.	.
cord-023443-pvz7dll9	572	1	However	however	RB
cord-023443-pvz7dll9	572	2	,	,	,
cord-023443-pvz7dll9	572	3	the	the	DT
cord-023443-pvz7dll9	572	4	increases	increase	NNS
cord-023443-pvz7dll9	572	5	of	of	IN
cord-023443-pvz7dll9	572	6	IFN	IFN	NNP
cord-023443-pvz7dll9	572	7	-	-	HYPH
cord-023443-pvz7dll9	572	8	g	g	NNP
cord-023443-pvz7dll9	572	9	and	and	CC
cord-023443-pvz7dll9	572	10	TNF	TNF	NNP
cord-023443-pvz7dll9	572	11	-	-	,
cord-023443-pvz7dll9	572	12	a	a	NNP
cord-023443-pvz7dll9	572	13	were	be	VBD
cord-023443-pvz7dll9	572	14	more	more	RBR
cord-023443-pvz7dll9	572	15	pronounced	pronounced	JJ
cord-023443-pvz7dll9	572	16	in	in	IN
cord-023443-pvz7dll9	572	17	wells	well	NNS
cord-023443-pvz7dll9	572	18	with	with	IN
cord-023443-pvz7dll9	572	19	autologous	autologous	JJ
cord-023443-pvz7dll9	572	20	bacteria	bacteria	NNS
cord-023443-pvz7dll9	572	21	than	than	IN
cord-023443-pvz7dll9	572	22	in	in	IN
cord-023443-pvz7dll9	572	23	wells	well	NNS
cord-023443-pvz7dll9	572	24	with	with	IN
cord-023443-pvz7dll9	572	25	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	572	26	spp	spp	NNS
cord-023443-pvz7dll9	572	27	.	.	.
cord-023443-pvz7dll9	573	1	The	the	DT
cord-023443-pvz7dll9	573	2	addition	addition	NN
cord-023443-pvz7dll9	573	3	of	of	IN
cord-023443-pvz7dll9	573	4	dendritic	dendritic	JJ
cord-023443-pvz7dll9	573	5	cells	cell	NNS
cord-023443-pvz7dll9	573	6	upregulated	upregulate	VBD
cord-023443-pvz7dll9	573	7	CD25	cd25	JJ
cord-023443-pvz7dll9	573	8	expression	expression	NN
cord-023443-pvz7dll9	573	9	without	without	IN
cord-023443-pvz7dll9	573	10	simultaneous	simultaneous	JJ
cord-023443-pvz7dll9	573	11	upregulation	upregulation	NN
cord-023443-pvz7dll9	573	12	of	of	IN
cord-023443-pvz7dll9	573	13	CD69	CD69	NNP
cord-023443-pvz7dll9	573	14	.	.	.
cord-023443-pvz7dll9	574	1	The	the	DT
cord-023443-pvz7dll9	574	2	upregulation	upregulation	NN
cord-023443-pvz7dll9	574	3	was	be	VBD
cord-023443-pvz7dll9	574	4	pronounced	pronounce	VBN
cord-023443-pvz7dll9	574	5	after	after	IN
cord-023443-pvz7dll9	574	6	stimulation	stimulation	NN
cord-023443-pvz7dll9	574	7	with	with	IN
cord-023443-pvz7dll9	574	8	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	574	9	rhamnosus	rhamnosus	NN
cord-023443-pvz7dll9	574	10	GG	GG	NNP
cord-023443-pvz7dll9	574	11	compared	compare	VBN
cord-023443-pvz7dll9	574	12	with	with	IN
cord-023443-pvz7dll9	574	13	autologous	autologous	JJ
cord-023443-pvz7dll9	574	14	bacteria	bacteria	NNS
cord-023443-pvz7dll9	574	15	and	and	CC
cord-023443-pvz7dll9	574	16	other	other	JJ
cord-023443-pvz7dll9	574	17	lactobacilli	lactobacillus	NNS
cord-023443-pvz7dll9	574	18	.	.	.
cord-023443-pvz7dll9	575	1	Discussion	discussion	NN
cord-023443-pvz7dll9	575	2	:	:	:
cord-023443-pvz7dll9	576	1	In	in	IN
cord-023443-pvz7dll9	576	2	presence	presence	NN
cord-023443-pvz7dll9	576	3	of	of	IN
cord-023443-pvz7dll9	576	4	dendritic	dendritic	JJ
cord-023443-pvz7dll9	576	5	cells	cell	NNS
cord-023443-pvz7dll9	576	6	,	,	,
cord-023443-pvz7dll9	576	7	autologous	autologous	JJ
cord-023443-pvz7dll9	576	8	bacteria	bacteria	NNS
cord-023443-pvz7dll9	576	9	induced	induce	VBD
cord-023443-pvz7dll9	576	10	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	576	11	cytokines	cytokine	NNS
cord-023443-pvz7dll9	576	12	,	,	,
cord-023443-pvz7dll9	576	13	while	while	IN
cord-023443-pvz7dll9	576	14	probiotics	probiotic	NNS
cord-023443-pvz7dll9	576	15	mainly	mainly	RB
cord-023443-pvz7dll9	576	16	induced	induce	VBN
cord-023443-pvz7dll9	576	17	regulatory	regulatory	JJ
cord-023443-pvz7dll9	576	18	cytokines	cytokine	NNS
cord-023443-pvz7dll9	576	19	.	.	.
cord-023443-pvz7dll9	577	1	Lactobacillus	lactobacillus	NN
cord-023443-pvz7dll9	577	2	rhamnosus	rhamnosus	NN
cord-023443-pvz7dll9	577	3	GG	GG	NNP
cord-023443-pvz7dll9	577	4	induced	induce	VBD
cord-023443-pvz7dll9	577	5	a	a	DT
cord-023443-pvz7dll9	577	6	regulatory	regulatory	JJ
cord-023443-pvz7dll9	577	7	phenotype	phenotype	NN
cord-023443-pvz7dll9	577	8	(	(	-LRB-
cord-023443-pvz7dll9	577	9	cd25	cd25	NN
cord-023443-pvz7dll9	577	10	þ	þ	NNP
cord-023443-pvz7dll9	577	11	)	)	-RRB-
cord-023443-pvz7dll9	577	12	,	,	,
cord-023443-pvz7dll9	577	13	in	in	IN
cord-023443-pvz7dll9	577	14	part	part	NN
cord-023443-pvz7dll9	577	15	mediated	mediate	VBN
cord-023443-pvz7dll9	577	16	by	by	IN
cord-023443-pvz7dll9	577	17	dendritic	dendritic	JJ
cord-023443-pvz7dll9	577	18	cells	cell	NNS
cord-023443-pvz7dll9	577	19	.	.	.
cord-023443-pvz7dll9	578	1	Future	future	JJ
cord-023443-pvz7dll9	578	2	studies	study	NNS
cord-023443-pvz7dll9	578	3	will	will	MD
cord-023443-pvz7dll9	578	4	address	address	VB
cord-023443-pvz7dll9	578	5	whether	whether	IN
cord-023443-pvz7dll9	578	6	this	this	DT
cord-023443-pvz7dll9	578	7	shift	shift	NN
cord-023443-pvz7dll9	578	8	to	to	IN
cord-023443-pvz7dll9	578	9	a	a	DT
cord-023443-pvz7dll9	578	10	CD25	CD25	NNP
cord-023443-pvz7dll9	578	11	þ	þ	NNP
cord-023443-pvz7dll9	578	12	phenotype	phenotype	NN
cord-023443-pvz7dll9	578	13	represents	represent	VBZ
cord-023443-pvz7dll9	578	14	a	a	DT
cord-023443-pvz7dll9	578	15	differentiation	differentiation	NN
cord-023443-pvz7dll9	578	16	into	into	IN
cord-023443-pvz7dll9	578	17	competent	competent	JJ
cord-023443-pvz7dll9	578	18	regulatory	regulatory	JJ
cord-023443-pvz7dll9	578	19	T	t	NN
cord-023443-pvz7dll9	578	20	cells	cell	NNS
cord-023443-pvz7dll9	578	21	.	.	.
cord-023443-pvz7dll9	579	1	In	in	IN
cord-023443-pvz7dll9	579	2	a	a	DT
cord-023443-pvz7dll9	579	3	clinical	clinical	JJ
cord-023443-pvz7dll9	579	4	context	context	NN
cord-023443-pvz7dll9	579	5	,	,	,
cord-023443-pvz7dll9	579	6	such	such	JJ
cord-023443-pvz7dll9	579	7	cells	cell	NNS
cord-023443-pvz7dll9	579	8	might	may	MD
cord-023443-pvz7dll9	579	9	be	be	VB
cord-023443-pvz7dll9	579	10	used	use	VBN
cord-023443-pvz7dll9	579	11	for	for	IN
cord-023443-pvz7dll9	579	12	treatment	treatment	NN
cord-023443-pvz7dll9	579	13	of	of	IN
cord-023443-pvz7dll9	579	14	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	579	15	diseases	disease	NNS
cord-023443-pvz7dll9	579	16	.	.	.
cord-023443-pvz7dll9	580	1	Protein	protein	NN
cord-023443-pvz7dll9	580	2	microarrays	microarray	NNS
cord-023443-pvz7dll9	580	3	will	will	MD
cord-023443-pvz7dll9	580	4	play	play	VB
cord-023443-pvz7dll9	580	5	a	a	DT
cord-023443-pvz7dll9	580	6	key	key	JJ
cord-023443-pvz7dll9	580	7	role	role	NN
cord-023443-pvz7dll9	580	8	in	in	IN
cord-023443-pvz7dll9	580	9	the	the	DT
cord-023443-pvz7dll9	580	10	postgenomic	postgenomic	NN
cord-023443-pvz7dll9	580	11	era	era	NN
cord-023443-pvz7dll9	580	12	and	and	CC
cord-023443-pvz7dll9	580	13	offer	offer	VB
cord-023443-pvz7dll9	580	14	a	a	DT
cord-023443-pvz7dll9	580	15	unique	unique	JJ
cord-023443-pvz7dll9	580	16	possibility	possibility	NN
cord-023443-pvz7dll9	580	17	to	to	TO
cord-023443-pvz7dll9	580	18	perform	perform	VB
cord-023443-pvz7dll9	580	19	highthroughput	highthroughput	NN
cord-023443-pvz7dll9	580	20	global	global	JJ
cord-023443-pvz7dll9	580	21	proteome	proteome	NN
cord-023443-pvz7dll9	580	22	analysis	analysis	NN
cord-023443-pvz7dll9	580	23	.	.	.
cord-023443-pvz7dll9	581	1	A	a	DT
cord-023443-pvz7dll9	581	2	chip	chip	NN
cord-023443-pvz7dll9	581	3	can	can	MD
cord-023443-pvz7dll9	581	4	be	be	VB
cord-023443-pvz7dll9	581	5	printed	print	VBN
cord-023443-pvz7dll9	581	6	with	with	IN
cord-023443-pvz7dll9	581	7	thousands	thousand	NNS
cord-023443-pvz7dll9	581	8	of	of	IN
cord-023443-pvz7dll9	581	9	protein	protein	NN
cord-023443-pvz7dll9	581	10	probes	probe	NNS
cord-023443-pvz7dll9	581	11	(	(	-LRB-
cord-023443-pvz7dll9	581	12	e.g.	e.g.	IN
cord-023443-pvz7dll9	581	13	antibodies	antibody	NNS
cord-023443-pvz7dll9	581	14	)	)	-RRB-
cord-023443-pvz7dll9	581	15	,	,	,
cord-023443-pvz7dll9	581	16	the	the	DT
cord-023443-pvz7dll9	581	17	biological	biological	JJ
cord-023443-pvz7dll9	581	18	sample	sample	NN
cord-023443-pvz7dll9	581	19	added	add	VBD
cord-023443-pvz7dll9	581	20	(	(	-LRB-
cord-023443-pvz7dll9	581	21	e.g.	e.g.	RB
cord-023443-pvz7dll9	581	22	a	a	DT
cord-023443-pvz7dll9	581	23	proteome	proteome	NN
cord-023443-pvz7dll9	581	24	)	)	-RRB-
cord-023443-pvz7dll9	581	25	and	and	CC
cord-023443-pvz7dll9	581	26	any	any	DT
cord-023443-pvz7dll9	581	27	binding	binding	NN
cord-023443-pvz7dll9	581	28	detected	detect	VBN
cord-023443-pvz7dll9	581	29	.	.	.
cord-023443-pvz7dll9	582	1	We	-PRON-	PRP
cord-023443-pvz7dll9	582	2	aim	aim	VBP
cord-023443-pvz7dll9	582	3	to	to	TO
cord-023443-pvz7dll9	582	4	develop	develop	VB
cord-023443-pvz7dll9	582	5	protein	protein	NN
cord-023443-pvz7dll9	582	6	microarrays	microarray	NNS
cord-023443-pvz7dll9	582	7	based	base	VBN
cord-023443-pvz7dll9	582	8	on	on	IN
cord-023443-pvz7dll9	582	9	human	human	JJ
cord-023443-pvz7dll9	582	10	recombinant	recombinant	JJ
cord-023443-pvz7dll9	582	11	scFv	scfv	JJ
cord-023443-pvz7dll9	582	12	antibody	antibody	NN
cord-023443-pvz7dll9	582	13	fragments	fragment	NNS
cord-023443-pvz7dll9	582	14	for	for	IN
cord-023443-pvz7dll9	582	15	global	global	JJ
cord-023443-pvz7dll9	582	16	proteome	proteome	NN
cord-023443-pvz7dll9	582	17	analysis	analysis	NN
cord-023443-pvz7dll9	582	18	.	.	.
cord-023443-pvz7dll9	583	1	The	the	DT
cord-023443-pvz7dll9	583	2	concept	concept	NN
cord-023443-pvz7dll9	583	3	of	of	IN
cord-023443-pvz7dll9	583	4	comparing	compare	VBG
cord-023443-pvz7dll9	583	5	proteomic	proteomic	JJ
cord-023443-pvz7dll9	583	6	maps	map	NNS
cord-023443-pvz7dll9	583	7	of	of	IN
cord-023443-pvz7dll9	583	8	healthy	healthy	JJ
cord-023443-pvz7dll9	583	9	versus	versus	IN
cord-023443-pvz7dll9	583	10	diseased	diseased	JJ
cord-023443-pvz7dll9	583	11	samples	sample	NNS
cord-023443-pvz7dll9	583	12	will	will	MD
cord-023443-pvz7dll9	583	13	allow	allow	VB
cord-023443-pvz7dll9	583	14	diseasespecific	diseasespecific	JJ
cord-023443-pvz7dll9	583	15	proteins	protein	NNS
cord-023443-pvz7dll9	583	16	to	to	TO
cord-023443-pvz7dll9	583	17	be	be	VB
cord-023443-pvz7dll9	583	18	detected	detect	VBN
cord-023443-pvz7dll9	583	19	.	.	.
cord-023443-pvz7dll9	584	1	In	in	IN
cord-023443-pvz7dll9	584	2	fact	fact	NN
cord-023443-pvz7dll9	584	3	,	,	,
cord-023443-pvz7dll9	584	4	antibody	antibody	NN
cord-023443-pvz7dll9	584	5	microarrays	microarray	NNS
cord-023443-pvz7dll9	584	6	will	will	MD
cord-023443-pvz7dll9	584	7	allow	allow	VB
cord-023443-pvz7dll9	584	8	us	-PRON-	PRP
cord-023443-pvz7dll9	584	9	to	to	TO
cord-023443-pvz7dll9	584	10	perform	perform	VB
cord-023443-pvz7dll9	584	11	comparative	comparative	JJ
cord-023443-pvz7dll9	584	12	proteome	proteome	NN
cord-023443-pvz7dll9	584	13	analysis	analysis	NN
cord-023443-pvz7dll9	584	14	on	on	IN
cord-023443-pvz7dll9	584	15	any	any	DT
cord-023443-pvz7dll9	584	16	sample	sample	NN
cord-023443-pvz7dll9	584	17	format	format	NN
cord-023443-pvz7dll9	584	18	in	in	IN
cord-023443-pvz7dll9	584	19	a	a	DT
cord-023443-pvz7dll9	584	20	species	species	NN
cord-023443-pvz7dll9	584	21	-	-	HYPH
cord-023443-pvz7dll9	584	22	independent	independent	JJ
cord-023443-pvz7dll9	584	23	manner	manner	NN
cord-023443-pvz7dll9	584	24	,	,	,
cord-023443-pvz7dll9	584	25	as	as	RB
cord-023443-pvz7dll9	584	26	long	long	RB
cord-023443-pvz7dll9	584	27	as	as	IN
cord-023443-pvz7dll9	584	28	a	a	DT
cord-023443-pvz7dll9	584	29	proteome	proteome	NN
cord-023443-pvz7dll9	584	30	can	can	MD
cord-023443-pvz7dll9	584	31	be	be	VB
cord-023443-pvz7dll9	584	32	isolated	isolate	VBN
cord-023443-pvz7dll9	584	33	.	.	.
cord-023443-pvz7dll9	585	1	However	however	RB
cord-023443-pvz7dll9	585	2	,	,	,
cord-023443-pvz7dll9	585	3	the	the	DT
cord-023443-pvz7dll9	585	4	complexity	complexity	NN
cord-023443-pvz7dll9	585	5	of	of	IN
cord-023443-pvz7dll9	585	6	proteomes	proteome	NNS
cord-023443-pvz7dll9	585	7	,	,	,
cord-023443-pvz7dll9	585	8	containing	contain	VBG
cord-023443-pvz7dll9	585	9	several	several	JJ
cord-023443-pvz7dll9	585	10	thousands	thousand	NNS
cord-023443-pvz7dll9	585	11	of	of	IN
cord-023443-pvz7dll9	585	12	different	different	JJ
cord-023443-pvz7dll9	585	13	proteins	protein	NNS
cord-023443-pvz7dll9	585	14	,	,	,
cord-023443-pvz7dll9	585	15	is	be	VBZ
cord-023443-pvz7dll9	585	16	a	a	DT
cord-023443-pvz7dll9	585	17	problem	problem	NN
cord-023443-pvz7dll9	585	18	.	.	.
cord-023443-pvz7dll9	586	1	Here	here	RB
cord-023443-pvz7dll9	586	2	,	,	,
cord-023443-pvz7dll9	586	3	we	-PRON-	PRP
cord-023443-pvz7dll9	586	4	have	have	VBP
cord-023443-pvz7dll9	586	5	designed	design	VBN
cord-023443-pvz7dll9	586	6	antibody	antibody	NN
cord-023443-pvz7dll9	586	7	microarrays	microarray	NNS
cord-023443-pvz7dll9	586	8	targeting	target	VBG
cord-023443-pvz7dll9	586	9	the	the	DT
cord-023443-pvz7dll9	586	10	water	water	NN
cord-023443-pvz7dll9	586	11	-	-	HYPH
cord-023443-pvz7dll9	586	12	soluble	soluble	JJ
cord-023443-pvz7dll9	586	13	fraction	fraction	NN
cord-023443-pvz7dll9	586	14	of	of	IN
cord-023443-pvz7dll9	586	15	a	a	DT
cord-023443-pvz7dll9	586	16	proteome	proteome	NN
cord-023443-pvz7dll9	586	17	.	.	.
cord-023443-pvz7dll9	587	1	To	to	IN
cord-023443-pvz7dll9	587	2	this	this	DT
cord-023443-pvz7dll9	587	3	end	end	NN
cord-023443-pvz7dll9	587	4	,	,	,
cord-023443-pvz7dll9	587	5	an	an	DT
cord-023443-pvz7dll9	587	6	anticytokine	anticytokine	JJ
cord-023443-pvz7dll9	587	7	antibody	antibody	NN
cord-023443-pvz7dll9	587	8	array	array	NN
cord-023443-pvz7dll9	587	9	was	be	VBD
cord-023443-pvz7dll9	587	10	developed	develop	VBN
cord-023443-pvz7dll9	587	11	and	and	CC
cord-023443-pvz7dll9	587	12	human	human	JJ
cord-023443-pvz7dll9	587	13	dendritic	dendritic	JJ
cord-023443-pvz7dll9	587	14	cells	cell	NNS
cord-023443-pvz7dll9	587	15	(	(	-LRB-
cord-023443-pvz7dll9	587	16	AEactivation	AEactivation	NNP
cord-023443-pvz7dll9	587	17	)	)	-RRB-
cord-023443-pvz7dll9	587	18	was	be	VBD
cord-023443-pvz7dll9	587	19	used	use	VBN
cord-023443-pvz7dll9	587	20	as	as	IN
cord-023443-pvz7dll9	587	21	model	model	NN
cord-023443-pvz7dll9	587	22	system	system	NN
cord-023443-pvz7dll9	587	23	.	.	.
cord-023443-pvz7dll9	588	1	The	the	DT
cord-023443-pvz7dll9	588	2	results	result	NNS
cord-023443-pvz7dll9	588	3	showed	show	VBD
cord-023443-pvz7dll9	588	4	that	that	IN
cord-023443-pvz7dll9	588	5	our	-PRON-	PRP$
cord-023443-pvz7dll9	588	6	antibody	antibody	NN
cord-023443-pvz7dll9	588	7	microarrays	microarray	NNS
cord-023443-pvz7dll9	588	8	could	could	MD
cord-023443-pvz7dll9	588	9	be	be	VB
cord-023443-pvz7dll9	588	10	used	use	VBN
cord-023443-pvz7dll9	588	11	to	to	TO
cord-023443-pvz7dll9	588	12	examine	examine	VB
cord-023443-pvz7dll9	588	13	the	the	DT
cord-023443-pvz7dll9	588	14	cytokine	cytokine	NN
cord-023443-pvz7dll9	588	15	profile	profile	NN
cord-023443-pvz7dll9	588	16	in	in	IN
cord-023443-pvz7dll9	588	17	complex	complex	JJ
cord-023443-pvz7dll9	588	18	samples	sample	NNS
cord-023443-pvz7dll9	588	19	.	.	.
cord-023443-pvz7dll9	589	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	589	2	,	,	,
cord-023443-pvz7dll9	589	3	we	-PRON-	PRP
cord-023443-pvz7dll9	589	4	have	have	VBP
cord-023443-pvz7dll9	589	5	taken	take	VBN
cord-023443-pvz7dll9	589	6	the	the	DT
cord-023443-pvz7dll9	589	7	first	first	JJ
cord-023443-pvz7dll9	589	8	steps	step	NNS
cord-023443-pvz7dll9	589	9	towards	towards	IN
cord-023443-pvz7dll9	589	10	comparing	compare	VBG
cord-023443-pvz7dll9	589	11	our	-PRON-	PRP$
cord-023443-pvz7dll9	589	12	results	result	NNS
cord-023443-pvz7dll9	589	13	with	with	IN
cord-023443-pvz7dll9	589	14	those	those	DT
cord-023443-pvz7dll9	589	15	of	of	IN
cord-023443-pvz7dll9	589	16	other	other	JJ
cord-023443-pvz7dll9	589	17	technologies	technology	NNS
cord-023443-pvz7dll9	589	18	on	on	IN
cord-023443-pvz7dll9	589	19	both	both	CC
cord-023443-pvz7dll9	589	20	the	the	DT
cord-023443-pvz7dll9	589	21	protein	protein	NN
cord-023443-pvz7dll9	589	22	and	and	CC
cord-023443-pvz7dll9	589	23	gene	gene	NN
cord-023443-pvz7dll9	589	24	level	level	NN
cord-023443-pvz7dll9	589	25	.	.	.
cord-023443-pvz7dll9	590	1	Due	due	IN
cord-023443-pvz7dll9	590	2	to	to	IN
cord-023443-pvz7dll9	590	3	the	the	DT
cord-023443-pvz7dll9	590	4	complexity	complexity	NN
cord-023443-pvz7dll9	590	5	of	of	IN
cord-023443-pvz7dll9	590	6	the	the	DT
cord-023443-pvz7dll9	590	7	model	model	NN
cord-023443-pvz7dll9	590	8	proteome	proteome	NN
cord-023443-pvz7dll9	590	9	,	,	,
cord-023443-pvz7dll9	590	10	we	-PRON-	PRP
cord-023443-pvz7dll9	590	11	also	also	RB
cord-023443-pvz7dll9	590	12	examined	examine	VBD
cord-023443-pvz7dll9	590	13	the	the	DT
cord-023443-pvz7dll9	590	14	possibility	possibility	NN
cord-023443-pvz7dll9	590	15	to	to	TO
cord-023443-pvz7dll9	590	16	prefractionate	prefractionate	VB
cord-023443-pvz7dll9	590	17	the	the	DT
cord-023443-pvz7dll9	590	18	proteome	proteome	NN
cord-023443-pvz7dll9	590	19	in	in	IN
cord-023443-pvz7dll9	590	20	a	a	DT
cord-023443-pvz7dll9	590	21	simple	simple	JJ
cord-023443-pvz7dll9	590	22	one	one	CD
cord-023443-pvz7dll9	590	23	-	-	HYPH
cord-023443-pvz7dll9	590	24	step	step	NN
cord-023443-pvz7dll9	590	25	procedure	procedure	NN
cord-023443-pvz7dll9	590	26	(	(	-LRB-
cord-023443-pvz7dll9	590	27	based	base	VBN
cord-023443-pvz7dll9	590	28	on	on	IN
cord-023443-pvz7dll9	590	29	size	size	NN
cord-023443-pvz7dll9	590	30	)	)	-RRB-
cord-023443-pvz7dll9	590	31	prior	prior	RB
cord-023443-pvz7dll9	590	32	to	to	IN
cord-023443-pvz7dll9	590	33	the	the	DT
cord-023443-pvz7dll9	590	34	labelling	labelling	NN
cord-023443-pvz7dll9	590	35	step	step	NN
cord-023443-pvz7dll9	590	36	.	.	.
cord-023443-pvz7dll9	591	1	In	in	IN
cord-023443-pvz7dll9	591	2	more	more	JJR
cord-023443-pvz7dll9	591	3	detail	detail	NN
cord-023443-pvz7dll9	591	4	,	,	,
cord-023443-pvz7dll9	591	5	the	the	DT
cord-023443-pvz7dll9	591	6	sample	sample	NN
cord-023443-pvz7dll9	591	7	proteome	proteome	NN
cord-023443-pvz7dll9	591	8	was	be	VBD
cord-023443-pvz7dll9	591	9	fractionated	fractionate	VBN
cord-023443-pvz7dll9	591	10	into	into	IN
cord-023443-pvz7dll9	591	11	two	two	CD
cord-023443-pvz7dll9	591	12	fractions	fraction	NNS
cord-023443-pvz7dll9	591	13	using	use	VBG
cord-023443-pvz7dll9	591	14	membrane	membrane	NN
cord-023443-pvz7dll9	591	15	devices	device	NNS
cord-023443-pvz7dll9	591	16	with	with	IN
cord-023443-pvz7dll9	591	17	different	different	JJ
cord-023443-pvz7dll9	591	18	molecular	molecular	JJ
cord-023443-pvz7dll9	591	19	weight	weight	NN
cord-023443-pvz7dll9	591	20	cut	cut	NN
cord-023443-pvz7dll9	591	21	-	-	HYPH
cord-023443-pvz7dll9	591	22	offs	off	NNS
cord-023443-pvz7dll9	591	23	.	.	.
cord-023443-pvz7dll9	592	1	The	the	DT
cord-023443-pvz7dll9	592	2	results	result	NNS
cord-023443-pvz7dll9	592	3	showed	show	VBD
cord-023443-pvz7dll9	592	4	that	that	IN
cord-023443-pvz7dll9	592	5	the	the	DT
cord-023443-pvz7dll9	592	6	fractionation	fractionation	NN
cord-023443-pvz7dll9	592	7	considerably	considerably	RB
cord-023443-pvz7dll9	592	8	enhanced	enhance	VBD
cord-023443-pvz7dll9	592	9	the	the	DT
cord-023443-pvz7dll9	592	10	assay	assay	NN
cord-023443-pvz7dll9	592	11	sensitivity	sensitivity	NN
cord-023443-pvz7dll9	592	12	allowing	allow	VBG
cord-023443-pvz7dll9	592	13	cytokines	cytokine	NNS
cord-023443-pvz7dll9	592	14	in	in	IN
cord-023443-pvz7dll9	592	15	the	the	DT
cord-023443-pvz7dll9	592	16	pg	pg	NN
cord-023443-pvz7dll9	592	17	/	/	SYM
cord-023443-pvz7dll9	592	18	ml	ml	NN
cord-023443-pvz7dll9	592	19	range	range	NN
cord-023443-pvz7dll9	592	20	to	to	TO
cord-023443-pvz7dll9	592	21	be	be	VB
cord-023443-pvz7dll9	592	22	readily	readily	RB
cord-023443-pvz7dll9	592	23	detectable	detectable	JJ
cord-023443-pvz7dll9	592	24	.	.	.
cord-023443-pvz7dll9	593	1	The	the	DT
cord-023443-pvz7dll9	593	2	Immunomodulatory	Immunomodulatory	NNP
cord-023443-pvz7dll9	593	3	Effect	Effect	NNP
cord-023443-pvz7dll9	593	4	of	of	IN
cord-023443-pvz7dll9	593	5	Heat	Heat	NNP
cord-023443-pvz7dll9	593	6	Shock	Shock	NNP
cord-023443-pvz7dll9	593	7	Protein	Protein	NNP
cord-023443-pvz7dll9	593	8	70	70	CD
cord-023443-pvz7dll9	593	9	:	:	:
cord-023443-pvz7dll9	593	10	Immunization	immunization	NN
cord-023443-pvz7dll9	593	11	with	with	IN
cord-023443-pvz7dll9	593	12	a	a	DT
cord-023443-pvz7dll9	593	13	DNA	dna	NN
cord-023443-pvz7dll9	593	14	Construct	construct	NN
cord-023443-pvz7dll9	593	15	Based	base	VBN
cord-023443-pvz7dll9	593	16	on	on	IN
cord-023443-pvz7dll9	593	17	the	the	DT
cord-023443-pvz7dll9	593	18	Malarial	Malarial	NNP
cord-023443-pvz7dll9	593	19	Antigen	Antigen	NNP
cord-023443-pvz7dll9	593	20	Fused	fuse	VBN
cord-023443-pvz7dll9	593	21	with	with	IN
cord-023443-pvz7dll9	593	22	a	a	DT
cord-023443-pvz7dll9	593	23	Fragment	Fragment	NNP
cord-023443-pvz7dll9	593	24	of	of	IN
cord-023443-pvz7dll9	593	25	HSP	HSP	NNP
cord-023443-pvz7dll9	593	26	70	70	CD
cord-023443-pvz7dll9	593	27	Primes	Primes	NNPS
cord-023443-pvz7dll9	593	28	for	for	IN
cord-023443-pvz7dll9	593	29	a	a	DT
cord-023443-pvz7dll9	593	30	Th-1	Th-1	NNP
cord-023443-pvz7dll9	593	31	Type	Type	NNP
cord-023443-pvz7dll9	593	32	of	of	IN
cord-023443-pvz7dll9	593	33	Response	Response	NNP
cord-023443-pvz7dll9	593	34	Finding	find	VBG
cord-023443-pvz7dll9	593	35	an	an	DT
cord-023443-pvz7dll9	593	36	appropriate	appropriate	JJ
cord-023443-pvz7dll9	593	37	adjuvant	adjuvant	NN
cord-023443-pvz7dll9	593	38	for	for	IN
cord-023443-pvz7dll9	593	39	human	human	JJ
cord-023443-pvz7dll9	593	40	vaccination	vaccination	NN
cord-023443-pvz7dll9	593	41	is	be	VBZ
cord-023443-pvz7dll9	593	42	crucial	crucial	JJ
cord-023443-pvz7dll9	593	43	.	.	.
cord-023443-pvz7dll9	594	1	Heat	heat	NN
cord-023443-pvz7dll9	594	2	shock	shock	NN
cord-023443-pvz7dll9	594	3	proteins	protein	NNS
cord-023443-pvz7dll9	594	4	(	(	-LRB-
cord-023443-pvz7dll9	594	5	HSPs	HSPs	NNP
cord-023443-pvz7dll9	594	6	)	)	-RRB-
cord-023443-pvz7dll9	594	7	act	act	VBP
cord-023443-pvz7dll9	594	8	as	as	IN
cord-023443-pvz7dll9	594	9	adjuvants	adjuvant	NNS
cord-023443-pvz7dll9	594	10	when	when	WRB
cord-023443-pvz7dll9	594	11	coadministered	coadministere	VBN
cord-023443-pvz7dll9	594	12	with	with	IN
cord-023443-pvz7dll9	594	13	peptide	peptide	NN
cord-023443-pvz7dll9	594	14	antigens	antigen	NNS
cord-023443-pvz7dll9	594	15	or	or	CC
cord-023443-pvz7dll9	594	16	given	give	VBN
cord-023443-pvz7dll9	594	17	as	as	IN
cord-023443-pvz7dll9	594	18	fusion	fusion	NN
cord-023443-pvz7dll9	594	19	proteins	protein	NNS
cord-023443-pvz7dll9	594	20	.	.	.
cord-023443-pvz7dll9	595	1	However	however	RB
cord-023443-pvz7dll9	595	2	,	,	,
cord-023443-pvz7dll9	595	3	there	there	EX
cord-023443-pvz7dll9	595	4	is	be	VBZ
cord-023443-pvz7dll9	595	5	a	a	DT
cord-023443-pvz7dll9	595	6	potential	potential	JJ
cord-023443-pvz7dll9	595	7	risk	risk	NN
cord-023443-pvz7dll9	595	8	of	of	IN
cord-023443-pvz7dll9	595	9	autoimmunity	autoimmunity	NN
cord-023443-pvz7dll9	595	10	when	when	WRB
cord-023443-pvz7dll9	595	11	using	use	VBG
cord-023443-pvz7dll9	595	12	the	the	DT
cord-023443-pvz7dll9	595	13	complete	complete	JJ
cord-023443-pvz7dll9	595	14	molecules	molecule	NNS
cord-023443-pvz7dll9	595	15	,	,	,
cord-023443-pvz7dll9	595	16	because	because	IN
cord-023443-pvz7dll9	595	17	HSPs	hsp	NNS
cord-023443-pvz7dll9	595	18	are	be	VBP
cord-023443-pvz7dll9	595	19	evolutionary	evolutionary	JJ
cord-023443-pvz7dll9	595	20	conserved	conserve	VBN
cord-023443-pvz7dll9	595	21	.	.	.
cord-023443-pvz7dll9	596	1	To	to	TO
cord-023443-pvz7dll9	596	2	overcome	overcome	VB
cord-023443-pvz7dll9	596	3	this	this	DT
cord-023443-pvz7dll9	596	4	,	,	,
cord-023443-pvz7dll9	596	5	we	-PRON-	PRP
cord-023443-pvz7dll9	596	6	first	first	RB
cord-023443-pvz7dll9	596	7	evaluated	evaluate	VBD
cord-023443-pvz7dll9	596	8	the	the	DT
cord-023443-pvz7dll9	596	9	adjuvant	adjuvant	JJ
cord-023443-pvz7dll9	596	10	effect	effect	NN
cord-023443-pvz7dll9	596	11	against	against	IN
cord-023443-pvz7dll9	596	12	two	two	CD
cord-023443-pvz7dll9	596	13	different	different	JJ
cord-023443-pvz7dll9	596	14	antigens	antigen	NNS
cord-023443-pvz7dll9	596	15	of	of	IN
cord-023443-pvz7dll9	596	16	a	a	DT
cord-023443-pvz7dll9	596	17	less	less	RBR
cord-023443-pvz7dll9	596	18	-	-	HYPH
cord-023443-pvz7dll9	596	19	conserved	conserve	VBN
cord-023443-pvz7dll9	596	20	fraction	fraction	NN
cord-023443-pvz7dll9	596	21	of	of	IN
cord-023443-pvz7dll9	596	22	Plasmodium	plasmodium	NN
cord-023443-pvz7dll9	596	23	falciparum	falciparum	NN
cord-023443-pvz7dll9	596	24	HSP70	HSP70	NNP
cord-023443-pvz7dll9	596	25	(	(	-LRB-
cord-023443-pvz7dll9	596	26	Pf70C	Pf70C	NNP
cord-023443-pvz7dll9	596	27	)	)	-RRB-
cord-023443-pvz7dll9	596	28	and	and	CC
cord-023443-pvz7dll9	596	29	compared	compare	VBD
cord-023443-pvz7dll9	596	30	it	-PRON-	PRP
cord-023443-pvz7dll9	596	31	to	to	IN
cord-023443-pvz7dll9	596	32	the	the	DT
cord-023443-pvz7dll9	596	33	whole	whole	JJ
cord-023443-pvz7dll9	596	34	HSP70	HSP70	NNP
cord-023443-pvz7dll9	596	35	molecule	molecule	NN
cord-023443-pvz7dll9	596	36	from	from	IN
cord-023443-pvz7dll9	596	37	Trypanosoma	Trypanosoma	NNP
cord-023443-pvz7dll9	596	38	cruzi	cruzi	NNP
cord-023443-pvz7dll9	596	39	(	(	-LRB-
cord-023443-pvz7dll9	596	40	TcHSP70	TcHSP70	NNP
cord-023443-pvz7dll9	596	41	)	)	-RRB-
cord-023443-pvz7dll9	596	42	.	.	.
cord-023443-pvz7dll9	597	1	We	-PRON-	PRP
cord-023443-pvz7dll9	597	2	found	find	VBD
cord-023443-pvz7dll9	597	3	that	that	IN
cord-023443-pvz7dll9	597	4	Pf70C	Pf70C	NNP
cord-023443-pvz7dll9	597	5	exhibited	exhibit	VBD
cord-023443-pvz7dll9	597	6	similar	similar	JJ
cord-023443-pvz7dll9	597	7	adjuvant	adjuvant	JJ
cord-023443-pvz7dll9	597	8	properties	property	NNS
cord-023443-pvz7dll9	597	9	as	as	IN
cord-023443-pvz7dll9	597	10	the	the	DT
cord-023443-pvz7dll9	597	11	whole	whole	JJ
cord-023443-pvz7dll9	597	12	molecule	molecule	NN
cord-023443-pvz7dll9	597	13	.	.	.
cord-023443-pvz7dll9	598	1	We	-PRON-	PRP
cord-023443-pvz7dll9	598	2	later	later	RB
cord-023443-pvz7dll9	598	3	evaluated	evaluate	VBD
cord-023443-pvz7dll9	598	4	the	the	DT
cord-023443-pvz7dll9	598	5	adjuvant	adjuvant	JJ
cord-023443-pvz7dll9	598	6	potential	potential	NN
cord-023443-pvz7dll9	598	7	of	of	IN
cord-023443-pvz7dll9	598	8	Pf70C	Pf70C	NNP
cord-023443-pvz7dll9	598	9	against	against	IN
cord-023443-pvz7dll9	598	10	the	the	DT
cord-023443-pvz7dll9	598	11	malarial	malarial	JJ
cord-023443-pvz7dll9	598	12	antigen	antigen	NN
cord-023443-pvz7dll9	599	1	EB200	eb200	UH
cord-023443-pvz7dll9	599	2	in	in	IN
cord-023443-pvz7dll9	599	3	a	a	DT
cord-023443-pvz7dll9	599	4	chimeric	chimeric	JJ
cord-023443-pvz7dll9	599	5	DNA	dna	NN
cord-023443-pvz7dll9	599	6	construct	construct	NN
cord-023443-pvz7dll9	599	7	.	.	.
cord-023443-pvz7dll9	600	1	No	no	DT
cord-023443-pvz7dll9	600	2	appreciable	appreciable	JJ
cord-023443-pvz7dll9	600	3	levels	level	NNS
cord-023443-pvz7dll9	600	4	of	of	IN
cord-023443-pvz7dll9	600	5	EB200-specific	EB200-specific	NNP
cord-023443-pvz7dll9	600	6	Abstracts	abstract	NNS
cord-023443-pvz7dll9	600	7	629	629	CD
cord-023443-pvz7dll9	600	8	..................................................................................................................................................................................................	..................................................................................................................................................................................................	.
cord-023443-pvz7dll9	601	1	antibodies	antibody	NNS
cord-023443-pvz7dll9	601	2	were	be	VBD
cord-023443-pvz7dll9	601	3	detected	detect	VBN
cord-023443-pvz7dll9	601	4	in	in	IN
cord-023443-pvz7dll9	601	5	mice	mouse	NNS
cord-023443-pvz7dll9	601	6	immunized	immunize	VBN
cord-023443-pvz7dll9	601	7	only	only	RB
cord-023443-pvz7dll9	601	8	with	with	IN
cord-023443-pvz7dll9	601	9	the	the	DT
cord-023443-pvz7dll9	601	10	DNA	dna	NN
cord-023443-pvz7dll9	601	11	constructs	construct	NNS
cord-023443-pvz7dll9	601	12	.	.	.
cord-023443-pvz7dll9	602	1	However	however	RB
cord-023443-pvz7dll9	602	2	,	,	,
cord-023443-pvz7dll9	602	3	DNA	DNA	NNP
cord-023443-pvz7dll9	602	4	primed	prime	VBD
cord-023443-pvz7dll9	602	5	the	the	DT
cord-023443-pvz7dll9	602	6	immune	immune	JJ
cord-023443-pvz7dll9	602	7	system	system	NN
cord-023443-pvz7dll9	602	8	,	,	,
cord-023443-pvz7dll9	602	9	because	because	IN
cord-023443-pvz7dll9	602	10	subsequent	subsequent	JJ
cord-023443-pvz7dll9	602	11	challenge	challenge	NN
cord-023443-pvz7dll9	602	12	with	with	IN
cord-023443-pvz7dll9	602	13	the	the	DT
cord-023443-pvz7dll9	602	14	corresponding	corresponding	JJ
cord-023443-pvz7dll9	602	15	recombinant	recombinant	JJ
cord-023443-pvz7dll9	602	16	fusion	fusion	NN
cord-023443-pvz7dll9	602	17	proteins	protein	NNS
cord-023443-pvz7dll9	602	18	elicited	elicit	VBD
cord-023443-pvz7dll9	602	19	a	a	DT
cord-023443-pvz7dll9	602	20	strong	strong	JJ
cord-023443-pvz7dll9	602	21	Th-1	Th-1	NNP
cord-023443-pvz7dll9	602	22	antibody	antibody	NN
cord-023443-pvz7dll9	602	23	response	response	NN
cord-023443-pvz7dll9	602	24	.	.	.
cord-023443-pvz7dll9	603	1	In	in	IN
cord-023443-pvz7dll9	603	2	contrast	contrast	NN
cord-023443-pvz7dll9	603	3	,	,	,
cord-023443-pvz7dll9	603	4	no	no	DT
cord-023443-pvz7dll9	603	5	priming	priming	NN
cord-023443-pvz7dll9	603	6	effect	effect	NN
cord-023443-pvz7dll9	603	7	was	be	VBD
cord-023443-pvz7dll9	603	8	observed	observe	VBN
cord-023443-pvz7dll9	603	9	for	for	IN
cord-023443-pvz7dll9	603	10	ex	ex	FW
cord-023443-pvz7dll9	603	11	vivo	vivo	NNP
cord-023443-pvz7dll9	603	12	IFN	IFN	NNP
cord-023443-pvz7dll9	603	13	-	-	HYPH
cord-023443-pvz7dll9	603	14	g	g	NN
cord-023443-pvz7dll9	603	15	production	production	NN
cord-023443-pvz7dll9	603	16	but	but	CC
cord-023443-pvz7dll9	603	17	stimulation	stimulation	NN
cord-023443-pvz7dll9	603	18	with	with	IN
cord-023443-pvz7dll9	603	19	the	the	DT
cord-023443-pvz7dll9	603	20	HSP	HSP	NNP
cord-023443-pvz7dll9	603	21	-	-	HYPH
cord-023443-pvz7dll9	603	22	chimeric	chimeric	JJ
cord-023443-pvz7dll9	603	23	fusion	fusion	NN
cord-023443-pvz7dll9	603	24	protein	protein	NN
cord-023443-pvz7dll9	603	25	induced	induce	VBD
cord-023443-pvz7dll9	603	26	a	a	DT
cord-023443-pvz7dll9	603	27	stronger	strong	JJR
cord-023443-pvz7dll9	603	28	secretion	secretion	NN
cord-023443-pvz7dll9	603	29	of	of	IN
cord-023443-pvz7dll9	603	30	IFN	IFN	NNP
cord-023443-pvz7dll9	603	31	-	-	HYPH
cord-023443-pvz7dll9	603	32	g	g	NNP
cord-023443-pvz7dll9	603	33	in	in	IN
cord-023443-pvz7dll9	603	34	vitro	vitro	FW
cord-023443-pvz7dll9	603	35	than	than	IN
cord-023443-pvz7dll9	603	36	other	other	JJ
cord-023443-pvz7dll9	603	37	proteins	protein	NNS
cord-023443-pvz7dll9	603	38	used	use	VBN
cord-023443-pvz7dll9	603	39	.	.	.
cord-023443-pvz7dll9	604	1	These	these	DT
cord-023443-pvz7dll9	604	2	results	result	NNS
cord-023443-pvz7dll9	604	3	indicate	indicate	VBP
cord-023443-pvz7dll9	604	4	that	that	IN
cord-023443-pvz7dll9	604	5	the	the	DT
cord-023443-pvz7dll9	604	6	use	use	NN
cord-023443-pvz7dll9	604	7	of	of	IN
cord-023443-pvz7dll9	604	8	HSPs	HSPs	NNP
cord-023443-pvz7dll9	604	9	is	be	VBZ
cord-023443-pvz7dll9	604	10	promising	promise	VBG
cord-023443-pvz7dll9	604	11	in	in	IN
cord-023443-pvz7dll9	604	12	the	the	DT
cord-023443-pvz7dll9	604	13	design	design	NN
cord-023443-pvz7dll9	604	14	of	of	IN
cord-023443-pvz7dll9	604	15	new	new	JJ
cord-023443-pvz7dll9	604	16	vaccines	vaccine	NNS
cord-023443-pvz7dll9	604	17	.	.	.
cord-023443-pvz7dll9	605	1	High	High	NNP
cord-023443-pvz7dll9	605	2	-	-	HYPH
cord-023443-pvz7dll9	605	3	Throughput	Throughput	NNP
cord-023443-pvz7dll9	605	4	Proteomics	Proteomics	NNP
cord-023443-pvz7dll9	605	5	on	on	IN
cord-023443-pvz7dll9	605	6	Antibody	Antibody	NNP
cord-023443-pvz7dll9	605	7	-	-	HYPH
cord-023443-pvz7dll9	605	8	based	base	VBN
cord-023443-pvz7dll9	605	9	Microarrays	microarray	NNS
cord-023443-pvz7dll9	605	10	:	:	:
cord-023443-pvz7dll9	605	11	the	the	DT
cord-023443-pvz7dll9	605	12	Importance	Importance	NNP
cord-023443-pvz7dll9	605	13	of	of	IN
cord-023443-pvz7dll9	605	14	Probe	Probe	NNP
cord-023443-pvz7dll9	605	15	and	and	CC
cord-023443-pvz7dll9	605	16	Surface	Surface	NNP
cord-023443-pvz7dll9	605	17	Design	Design	NNP
cord-023443-pvz7dll9	606	1	In	in	IN
cord-023443-pvz7dll9	606	2	analogy	analogy	NN
cord-023443-pvz7dll9	606	3	to	to	IN
cord-023443-pvz7dll9	606	4	DNA	dna	NN
cord-023443-pvz7dll9	606	5	microarrays	microarray	NNS
cord-023443-pvz7dll9	606	6	,	,	,
cord-023443-pvz7dll9	606	7	protein	protein	NN
cord-023443-pvz7dll9	606	8	microarrays	microarray	NNS
cord-023443-pvz7dll9	606	9	offer	offer	VBP
cord-023443-pvz7dll9	606	10	a	a	DT
cord-023443-pvz7dll9	606	11	new	new	JJ
cord-023443-pvz7dll9	606	12	distinct	distinct	JJ
cord-023443-pvz7dll9	606	13	possibility	possibility	NN
cord-023443-pvz7dll9	606	14	to	to	TO
cord-023443-pvz7dll9	606	15	perform	perform	VB
cord-023443-pvz7dll9	606	16	sensitive	sensitive	JJ
cord-023443-pvz7dll9	606	17	highthroughput	highthroughput	NN
cord-023443-pvz7dll9	606	18	global	global	JJ
cord-023443-pvz7dll9	606	19	proteome	proteome	NN
cord-023443-pvz7dll9	606	20	analysis	analysis	NN
cord-023443-pvz7dll9	606	21	.	.	.
cord-023443-pvz7dll9	607	1	However	however	RB
cord-023443-pvz7dll9	607	2	,	,	,
cord-023443-pvz7dll9	607	3	the	the	DT
cord-023443-pvz7dll9	607	4	development	development	NN
cord-023443-pvz7dll9	607	5	of	of	IN
cord-023443-pvz7dll9	607	6	the	the	DT
cord-023443-pvz7dll9	607	7	protein	protein	NN
cord-023443-pvz7dll9	607	8	microarray	microarray	NN
cord-023443-pvz7dll9	607	9	technology	technology	NN
cord-023443-pvz7dll9	607	10	will	will	MD
cord-023443-pvz7dll9	607	11	place	place	VB
cord-023443-pvz7dll9	607	12	high	high	JJ
cord-023443-pvz7dll9	607	13	demands	demand	NNS
cord-023443-pvz7dll9	607	14	upon	upon	IN
cord-023443-pvz7dll9	607	15	the	the	DT
cord-023443-pvz7dll9	607	16	design	design	NN
cord-023443-pvz7dll9	607	17	of	of	IN
cord-023443-pvz7dll9	607	18	both	both	DT
cord-023443-pvz7dll9	607	19	probes	probe	NNS
cord-023443-pvz7dll9	607	20	and	and	CC
cord-023443-pvz7dll9	607	21	solid	solid	JJ
cord-023443-pvz7dll9	607	22	supports	support	NNS
cord-023443-pvz7dll9	607	23	.	.	.
cord-023443-pvz7dll9	608	1	The	the	DT
cord-023443-pvz7dll9	608	2	analysis	analysis	NN
cord-023443-pvz7dll9	608	3	of	of	IN
cord-023443-pvz7dll9	608	4	thousands	thousand	NNS
cord-023443-pvz7dll9	608	5	of	of	IN
cord-023443-pvz7dll9	608	6	heterogeneous	heterogeneous	JJ
cord-023443-pvz7dll9	608	7	proteins	protein	NNS
cord-023443-pvz7dll9	608	8	on	on	IN
cord-023443-pvz7dll9	608	9	a	a	DT
cord-023443-pvz7dll9	608	10	single	single	JJ
cord-023443-pvz7dll9	608	11	microarray	microarray	NN
cord-023443-pvz7dll9	608	12	requires	require	VBZ
cord-023443-pvz7dll9	608	13	the	the	DT
cord-023443-pvz7dll9	608	14	use	use	NN
cord-023443-pvz7dll9	608	15	of	of	IN
cord-023443-pvz7dll9	608	16	uniform	uniform	JJ
cord-023443-pvz7dll9	608	17	probes	probe	NNS
cord-023443-pvz7dll9	608	18	,	,	,
cord-023443-pvz7dll9	608	19	such	such	JJ
cord-023443-pvz7dll9	608	20	as	as	IN
cord-023443-pvz7dll9	608	21	antibodies	antibody	NNS
cord-023443-pvz7dll9	608	22	,	,	,
cord-023443-pvz7dll9	608	23	directly	directly	RB
cord-023443-pvz7dll9	608	24	designed	design	VBN
cord-023443-pvz7dll9	608	25	for	for	IN
cord-023443-pvz7dll9	608	26	protein	protein	NN
cord-023443-pvz7dll9	608	27	microarray	microarray	NN
cord-023443-pvz7dll9	608	28	applications	application	NNS
cord-023443-pvz7dll9	608	29	.	.	.
cord-023443-pvz7dll9	609	1	We	-PRON-	PRP
cord-023443-pvz7dll9	609	2	have	have	VBP
cord-023443-pvz7dll9	609	3	recently	recently	RB
cord-023443-pvz7dll9	609	4	generated	generate	VBN
cord-023443-pvz7dll9	609	5	a	a	DT
cord-023443-pvz7dll9	609	6	human	human	JJ
cord-023443-pvz7dll9	609	7	recombinant	recombinant	JJ
cord-023443-pvz7dll9	609	8	single	single	JJ
cord-023443-pvz7dll9	609	9	-	-	HYPH
cord-023443-pvz7dll9	609	10	chain	chain	NN
cord-023443-pvz7dll9	609	11	Fv	Fv	NNP
cord-023443-pvz7dll9	609	12	antibody	antibody	NN
cord-023443-pvz7dll9	609	13	library	library	NN
cord-023443-pvz7dll9	609	14	,	,	,
cord-023443-pvz7dll9	609	15	genetically	genetically	RB
cord-023443-pvz7dll9	609	16	constructed	construct	VBN
cord-023443-pvz7dll9	609	17	around	around	IN
cord-023443-pvz7dll9	609	18	one	one	CD
cord-023443-pvz7dll9	609	19	framework	framework	NN
cord-023443-pvz7dll9	609	20	,	,	,
cord-023443-pvz7dll9	609	21	the	the	DT
cord-023443-pvz7dll9	609	22	nCoDeR	nCoDeR	NNP
cord-023443-pvz7dll9	609	23	-	-	HYPH
cord-023443-pvz7dll9	609	24	library	library	NN
cord-023443-pvz7dll9	609	25	,	,	,
cord-023443-pvz7dll9	609	26	containing	contain	VBG
cord-023443-pvz7dll9	609	27	2	2	CD
cord-023443-pvz7dll9	609	28	Â	â	CD
cord-023443-pvz7dll9	609	29	1010	1010	CD
cord-023443-pvz7dll9	609	30	clones	clone	NNS
cord-023443-pvz7dll9	609	31	.	.	.
cord-023443-pvz7dll9	610	1	Single	single	JJ
cord-023443-pvz7dll9	610	2	framework	framework	NN
cord-023443-pvz7dll9	610	3	antibody	antibody	NN
cord-023443-pvz7dll9	610	4	fragments	fragment	NNS
cord-023443-pvz7dll9	610	5	(	(	-LRB-
cord-023443-pvz7dll9	610	6	sinFabs	sinFabs	NFP
cord-023443-pvz7dll9	610	7	)	)	-RRB-
cord-023443-pvz7dll9	610	8	selected	select	VBN
cord-023443-pvz7dll9	610	9	from	from	IN
cord-023443-pvz7dll9	610	10	this	this	DT
cord-023443-pvz7dll9	610	11	library	library	NN
cord-023443-pvz7dll9	610	12	were	be	VBD
cord-023443-pvz7dll9	610	13	successfully	successfully	RB
cord-023443-pvz7dll9	610	14	applied	apply	VBN
cord-023443-pvz7dll9	610	15	as	as	IN
cord-023443-pvz7dll9	610	16	probes	probe	NNS
cord-023443-pvz7dll9	610	17	for	for	IN
cord-023443-pvz7dll9	610	18	microarrays	microarray	NNS
cord-023443-pvz7dll9	610	19	providing	provide	VBG
cord-023443-pvz7dll9	610	20	sensitive	sensitive	JJ
cord-023443-pvz7dll9	610	21	detection	detection	NN
cord-023443-pvz7dll9	610	22	in	in	IN
cord-023443-pvz7dll9	610	23	the	the	DT
cord-023443-pvz7dll9	610	24	600	600	CD
cord-023443-pvz7dll9	610	25	attomol	attomol	JJ
cord-023443-pvz7dll9	610	26	(	(	-LRB-
cord-023443-pvz7dll9	610	27	mass	mass	NNP
cord-023443-pvz7dll9	610	28	spectrometry	spectrometry	NNP
cord-023443-pvz7dll9	610	29	)	)	-RRB-
cord-023443-pvz7dll9	610	30	and	and	CC
cord-023443-pvz7dll9	610	31	the	the	DT
cord-023443-pvz7dll9	610	32	300	300	CD
cord-023443-pvz7dll9	610	33	zeptomole	zeptomole	NN
cord-023443-pvz7dll9	610	34	range	range	NN
cord-023443-pvz7dll9	610	35	(	(	-LRB-
cord-023443-pvz7dll9	610	36	fluorescence	fluorescence	NN
cord-023443-pvz7dll9	610	37	)	)	-RRB-
cord-023443-pvz7dll9	610	38	.	.	.
cord-023443-pvz7dll9	611	1	However	however	RB
cord-023443-pvz7dll9	611	2	,	,	,
cord-023443-pvz7dll9	611	3	the	the	DT
cord-023443-pvz7dll9	611	4	choice	choice	NN
cord-023443-pvz7dll9	611	5	of	of	IN
cord-023443-pvz7dll9	611	6	framework	framework	NN
cord-023443-pvz7dll9	611	7	is	be	VBZ
cord-023443-pvz7dll9	611	8	critical	critical	JJ
cord-023443-pvz7dll9	611	9	.	.	.
cord-023443-pvz7dll9	612	1	We	-PRON-	PRP
cord-023443-pvz7dll9	612	2	have	have	VBP
cord-023443-pvz7dll9	612	3	shown	show	VBN
cord-023443-pvz7dll9	612	4	that	that	IN
cord-023443-pvz7dll9	612	5	the	the	DT
cord-023443-pvz7dll9	612	6	selected	selected	JJ
cord-023443-pvz7dll9	612	7	nCoDeR	nCoDeR	NNP
cord-023443-pvz7dll9	612	8	framework	framework	NN
cord-023443-pvz7dll9	612	9	displayed	display	VBD
cord-023443-pvz7dll9	612	10	excellent	excellent	JJ
cord-023443-pvz7dll9	612	11	functional	functional	JJ
cord-023443-pvz7dll9	612	12	on	on	IN
cord-023443-pvz7dll9	612	13	-	-	HYPH
cord-023443-pvz7dll9	612	14	chip	chip	NN
cord-023443-pvz7dll9	612	15	stability	stability	NN
cord-023443-pvz7dll9	612	16	and	and	CC
cord-023443-pvz7dll9	612	17	arrayed	array	VBD
cord-023443-pvz7dll9	612	18	dehydrated	dehydrated	JJ
cord-023443-pvz7dll9	612	19	probes	probe	NNS
cord-023443-pvz7dll9	612	20	retained	retain	VBD
cord-023443-pvz7dll9	612	21	their	-PRON-	PRP$
cord-023443-pvz7dll9	612	22	activity	activity	NN
cord-023443-pvz7dll9	612	23	for	for	IN
cord-023443-pvz7dll9	612	24	several	several	JJ
cord-023443-pvz7dll9	612	25	months	month	NNS
cord-023443-pvz7dll9	612	26	.	.	.
cord-023443-pvz7dll9	613	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	613	2	,	,	,
cord-023443-pvz7dll9	613	3	we	-PRON-	PRP
cord-023443-pvz7dll9	613	4	have	have	VBP
cord-023443-pvz7dll9	613	5	addressed	address	VBN
cord-023443-pvz7dll9	613	6	the	the	DT
cord-023443-pvz7dll9	613	7	issues	issue	NNS
cord-023443-pvz7dll9	613	8	of	of	IN
cord-023443-pvz7dll9	613	9	biocompatibility	biocompatibility	NN
cord-023443-pvz7dll9	613	10	of	of	IN
cord-023443-pvz7dll9	613	11	the	the	DT
cord-023443-pvz7dll9	613	12	solid	solid	JJ
cord-023443-pvz7dll9	613	13	support	support	NN
cord-023443-pvz7dll9	613	14	and	and	CC
cord-023443-pvz7dll9	613	15	immobilization	immobilization	NN
cord-023443-pvz7dll9	613	16	strategies	strategy	NNS
cord-023443-pvz7dll9	613	17	for	for	IN
cord-023443-pvz7dll9	613	18	our	-PRON-	PRP$
cord-023443-pvz7dll9	613	19	microarray	microarray	NN
cord-023443-pvz7dll9	613	20	setup	setup	NN
cord-023443-pvz7dll9	613	21	.	.	.
cord-023443-pvz7dll9	614	1	An	an	DT
cord-023443-pvz7dll9	614	2	in	in	IN
cord-023443-pvz7dll9	614	3	-	-	HYPH
cord-023443-pvz7dll9	614	4	house	house	NN
cord-023443-pvz7dll9	614	5	-	-	HYPH
cord-023443-pvz7dll9	614	6	designed	design	VBN
cord-023443-pvz7dll9	614	7	substrate	substrate	NN
cord-023443-pvz7dll9	614	8	,	,	,
cord-023443-pvz7dll9	614	9	macroporous	macroporous	JJ
cord-023443-pvz7dll9	614	10	silicon	silicon	NN
cord-023443-pvz7dll9	614	11	coated	coat	VBN
cord-023443-pvz7dll9	614	12	with	with	IN
cord-023443-pvz7dll9	614	13	nitrocellulose	nitrocellulose	NNS
cord-023443-pvz7dll9	614	14	(	(	-LRB-
cord-023443-pvz7dll9	614	15	MAP3-NC7	MAP3-NC7	NNP
cord-023443-pvz7dll9	614	16	)	)	-RRB-
cord-023443-pvz7dll9	614	17	,	,	,
cord-023443-pvz7dll9	614	18	displayed	display	VBD
cord-023443-pvz7dll9	614	19	properties	property	NNS
cord-023443-pvz7dll9	614	20	equal	equal	JJ
cord-023443-pvz7dll9	614	21	to	to	IN
cord-023443-pvz7dll9	614	22	,	,	,
cord-023443-pvz7dll9	614	23	or	or	CC
cord-023443-pvz7dll9	614	24	better	well	JJR
cord-023443-pvz7dll9	614	25	than	than	IN
cord-023443-pvz7dll9	614	26	,	,	,
cord-023443-pvz7dll9	614	27	those	those	DT
cord-023443-pvz7dll9	614	28	of	of	IN
cord-023443-pvz7dll9	614	29	five	five	CD
cord-023443-pvz7dll9	614	30	commercially	commercially	RB
cord-023443-pvz7dll9	614	31	available	available	JJ
cord-023443-pvz7dll9	614	32	supports	support	NNS
cord-023443-pvz7dll9	614	33	used	use	VBN
cord-023443-pvz7dll9	614	34	as	as	IN
cord-023443-pvz7dll9	614	35	reference	reference	NN
cord-023443-pvz7dll9	614	36	surfaces	surface	NNS
cord-023443-pvz7dll9	614	37	.	.	.
cord-023443-pvz7dll9	615	1	We	-PRON-	PRP
cord-023443-pvz7dll9	615	2	have	have	VBP
cord-023443-pvz7dll9	615	3	also	also	RB
cord-023443-pvz7dll9	615	4	evaluated	evaluate	VBN
cord-023443-pvz7dll9	615	5	different	different	JJ
cord-023443-pvz7dll9	615	6	coupling	coupling	NN
cord-023443-pvz7dll9	615	7	strategies	strategy	NNS
cord-023443-pvz7dll9	615	8	,	,	,
cord-023443-pvz7dll9	615	9	such	such	JJ
cord-023443-pvz7dll9	615	10	as	as	IN
cord-023443-pvz7dll9	615	11	adsorption	adsorption	NN
cord-023443-pvz7dll9	615	12	,	,	,
cord-023443-pvz7dll9	615	13	covalent	covalent	JJ
cord-023443-pvz7dll9	615	14	coupling	coupling	NN
cord-023443-pvz7dll9	615	15	,	,	,
cord-023443-pvz7dll9	615	16	diffusion	diffusion	NN
cord-023443-pvz7dll9	615	17	and	and	CC
cord-023443-pvz7dll9	615	18	affinity	affinity	NN
cord-023443-pvz7dll9	615	19	coupling	coupling	NN
cord-023443-pvz7dll9	615	20	.	.	.
cord-023443-pvz7dll9	616	1	Using	use	VBG
cord-023443-pvz7dll9	616	2	a	a	DT
cord-023443-pvz7dll9	616	3	novel	novel	JJ
cord-023443-pvz7dll9	616	4	affinity	affinity	NN
cord-023443-pvz7dll9	616	5	tag	tag	NN
cord-023443-pvz7dll9	616	6	,	,	,
cord-023443-pvz7dll9	616	7	the	the	DT
cord-023443-pvz7dll9	616	8	double-(his)6-tag	double-(his)6-tag	NN
cord-023443-pvz7dll9	616	9	,	,	,
cord-023443-pvz7dll9	616	10	we	-PRON-	PRP
cord-023443-pvz7dll9	616	11	increased	increase	VBD
cord-023443-pvz7dll9	616	12	the	the	DT
cord-023443-pvz7dll9	616	13	binding	binding	JJ
cord-023443-pvz7dll9	616	14	efficiency	efficiency	NN
cord-023443-pvz7dll9	616	15	of	of	IN
cord-023443-pvz7dll9	616	16	sinFab	sinfab	NN
cord-023443-pvz7dll9	616	17	-	-	HYPH
cord-023443-pvz7dll9	616	18	molecules	molecule	NNS
cord-023443-pvz7dll9	616	19	to	to	TO
cord-023443-pvz7dll9	616	20	Ni2	ni2	VB
cord-023443-pvz7dll9	616	21	þ	þ	NNP
cord-023443-pvz7dll9	616	22	-coated	-coated	JJ
cord-023443-pvz7dll9	616	23	solid	solid	JJ
cord-023443-pvz7dll9	616	24	supports	support	NNS
cord-023443-pvz7dll9	616	25	,	,	,
cord-023443-pvz7dll9	616	26	thereby	thereby	RB
cord-023443-pvz7dll9	616	27	allowing	allow	VBG
cord-023443-pvz7dll9	616	28	nonpurified	nonpurifie	VBN
cord-023443-pvz7dll9	616	29	probes	probe	NNS
cord-023443-pvz7dll9	616	30	to	to	TO
cord-023443-pvz7dll9	616	31	be	be	VB
cord-023443-pvz7dll9	616	32	directly	directly	RB
cord-023443-pvz7dll9	616	33	applied	apply	VBN
cord-023443-pvz7dll9	616	34	.	.	.
cord-023443-pvz7dll9	617	1	The	the	DT
cord-023443-pvz7dll9	617	2	mannan	mannan	NN
cord-023443-pvz7dll9	617	3	-	-	HYPH
cord-023443-pvz7dll9	617	4	binding	bind	VBG
cord-023443-pvz7dll9	617	5	lectin	lectin	NN
cord-023443-pvz7dll9	617	6	(	(	-LRB-
cord-023443-pvz7dll9	617	7	MBL	MBL	NNP
cord-023443-pvz7dll9	617	8	)	)	-RRB-
cord-023443-pvz7dll9	617	9	pathway	pathway	NN
cord-023443-pvz7dll9	617	10	is	be	VBZ
cord-023443-pvz7dll9	617	11	part	part	NN
cord-023443-pvz7dll9	617	12	of	of	IN
cord-023443-pvz7dll9	617	13	the	the	DT
cord-023443-pvz7dll9	617	14	innate	innate	JJ
cord-023443-pvz7dll9	617	15	immune	immune	JJ
cord-023443-pvz7dll9	617	16	system	system	NN
cord-023443-pvz7dll9	617	17	providing	provide	VBG
cord-023443-pvz7dll9	617	18	a	a	DT
cord-023443-pvz7dll9	617	19	first	first	JJ
cord-023443-pvz7dll9	617	20	line	line	NN
cord-023443-pvz7dll9	617	21	of	of	IN
cord-023443-pvz7dll9	617	22	defence	defence	NN
cord-023443-pvz7dll9	617	23	against	against	IN
cord-023443-pvz7dll9	617	24	infections	infection	NNS
cord-023443-pvz7dll9	617	25	.	.	.
cord-023443-pvz7dll9	618	1	MBL	MBL	NNP
cord-023443-pvz7dll9	618	2	and	and	CC
cord-023443-pvz7dll9	618	3	ficolins	ficolin	NNS
cord-023443-pvz7dll9	618	4	circulate	circulate	VBP
cord-023443-pvz7dll9	618	5	in	in	IN
cord-023443-pvz7dll9	618	6	complexes	complex	NNS
cord-023443-pvz7dll9	618	7	with	with	IN
cord-023443-pvz7dll9	618	8	MBL	MBL	NNP
cord-023443-pvz7dll9	618	9	-	-	HYPH
cord-023443-pvz7dll9	618	10	associated	associate	VBN
cord-023443-pvz7dll9	618	11	serine	serine	NN
cord-023443-pvz7dll9	618	12	proteases	protease	NNS
cord-023443-pvz7dll9	618	13	(	(	-LRB-
cord-023443-pvz7dll9	618	14	MASP-1	MASP-1	NNP
cord-023443-pvz7dll9	618	15	,	,	,
cord-023443-pvz7dll9	618	16	-2	-2	NNP
cord-023443-pvz7dll9	618	17	and	and	CC
cord-023443-pvz7dll9	618	18	-3	-3	NNP
cord-023443-pvz7dll9	618	19	)	)	-RRB-
cord-023443-pvz7dll9	618	20	.	.	.
cord-023443-pvz7dll9	619	1	After	after	IN
cord-023443-pvz7dll9	619	2	recognition	recognition	NN
cord-023443-pvz7dll9	619	3	of	of	IN
cord-023443-pvz7dll9	619	4	a	a	DT
cord-023443-pvz7dll9	619	5	microorganism	microorganism	NN
cord-023443-pvz7dll9	619	6	by	by	IN
cord-023443-pvz7dll9	619	7	MBL	MBL	NNP
cord-023443-pvz7dll9	619	8	,	,	,
cord-023443-pvz7dll9	619	9	activation	activation	NN
cord-023443-pvz7dll9	619	10	of	of	IN
cord-023443-pvz7dll9	619	11	the	the	DT
cord-023443-pvz7dll9	619	12	complement	complement	JJ
cord-023443-pvz7dll9	619	13	system	system	NN
cord-023443-pvz7dll9	619	14	occurs	occur	VBZ
cord-023443-pvz7dll9	619	15	.	.	.
cord-023443-pvz7dll9	620	1	MASP-1	MASP-1	NNP
cord-023443-pvz7dll9	620	2	and	and	CC
cord-023443-pvz7dll9	620	3	MASP-3	MASP-3	NNP
cord-023443-pvz7dll9	620	4	share	share	VBP
cord-023443-pvz7dll9	620	5	five	five	CD
cord-023443-pvz7dll9	620	6	domains	domain	NNS
cord-023443-pvz7dll9	620	7	(	(	-LRB-
cord-023443-pvz7dll9	620	8	making	make	VBG
cord-023443-pvz7dll9	620	9	up	up	RP
cord-023443-pvz7dll9	620	10	the	the	DT
cord-023443-pvz7dll9	620	11	so	so	RB
cord-023443-pvz7dll9	620	12	-	-	HYPH
cord-023443-pvz7dll9	620	13	called	call	VBN
cord-023443-pvz7dll9	620	14	A	a	NN
cord-023443-pvz7dll9	620	15	-	-	HYPH
cord-023443-pvz7dll9	620	16	chain	chain	NN
cord-023443-pvz7dll9	620	17	)	)	-RRB-
cord-023443-pvz7dll9	620	18	,	,	,
cord-023443-pvz7dll9	620	19	whereas	whereas	IN
cord-023443-pvz7dll9	620	20	they	-PRON-	PRP
cord-023443-pvz7dll9	620	21	have	have	VBP
cord-023443-pvz7dll9	620	22	unique	unique	JJ
cord-023443-pvz7dll9	620	23	protease	protease	NN
cord-023443-pvz7dll9	620	24	domains	domain	NNS
cord-023443-pvz7dll9	620	25	(	(	-LRB-
cord-023443-pvz7dll9	620	26	B	b	NN
cord-023443-pvz7dll9	620	27	-	-	HYPH
cord-023443-pvz7dll9	620	28	chains	chain	NNS
cord-023443-pvz7dll9	620	29	)	)	-RRB-
cord-023443-pvz7dll9	620	30	.	.	.
cord-023443-pvz7dll9	621	1	Before	before	IN
cord-023443-pvz7dll9	621	2	the	the	DT
cord-023443-pvz7dll9	621	3	identification	identification	NN
cord-023443-pvz7dll9	621	4	of	of	IN
cord-023443-pvz7dll9	621	5	MASP-3	MASP-3	NNP
cord-023443-pvz7dll9	621	6	,	,	,
cord-023443-pvz7dll9	621	7	an	an	DT
cord-023443-pvz7dll9	621	8	assay	assay	NN
cord-023443-pvz7dll9	621	9	for	for	IN
cord-023443-pvz7dll9	621	10	MASP	MASP	NNP
cord-023443-pvz7dll9	621	11	was	be	VBD
cord-023443-pvz7dll9	621	12	presented	present	VBN
cord-023443-pvz7dll9	621	13	,	,	,
cord-023443-pvz7dll9	621	14	based	base	VBN
cord-023443-pvz7dll9	621	15	on	on	IN
cord-023443-pvz7dll9	621	16	antibodies	antibody	NNS
cord-023443-pvz7dll9	621	17	against	against	IN
cord-023443-pvz7dll9	621	18	the	the	DT
cord-023443-pvz7dll9	621	19	A	A	NNP
cord-023443-pvz7dll9	621	20	-	-	HYPH
cord-023443-pvz7dll9	621	21	chain	chain	NN
cord-023443-pvz7dll9	621	22	of	of	IN
cord-023443-pvz7dll9	621	23	MASP-1	MASP-1	NNP
cord-023443-pvz7dll9	621	24	.	.	.
cord-023443-pvz7dll9	622	1	With	with	IN
cord-023443-pvz7dll9	622	2	the	the	DT
cord-023443-pvz7dll9	622	3	new	new	JJ
cord-023443-pvz7dll9	622	4	knowledge	knowledge	NN
cord-023443-pvz7dll9	622	5	of	of	IN
cord-023443-pvz7dll9	622	6	the	the	DT
cord-023443-pvz7dll9	622	7	three	three	CD
cord-023443-pvz7dll9	622	8	MASPs	masp	NNS
cord-023443-pvz7dll9	622	9	,	,	,
cord-023443-pvz7dll9	622	10	and	and	CC
cord-023443-pvz7dll9	622	11	the	the	DT
cord-023443-pvz7dll9	622	12	sharing	sharing	NN
cord-023443-pvz7dll9	622	13	of	of	IN
cord-023443-pvz7dll9	622	14	domains	domain	NNS
cord-023443-pvz7dll9	622	15	by	by	IN
cord-023443-pvz7dll9	622	16	MASP-1	MASP-1	NNP
cord-023443-pvz7dll9	622	17	and	and	CC
cord-023443-pvz7dll9	622	18	MASP-3	MASP-3	NNP
cord-023443-pvz7dll9	622	19	,	,	,
cord-023443-pvz7dll9	622	20	assays	assay	NNS
cord-023443-pvz7dll9	622	21	specific	specific	JJ
cord-023443-pvz7dll9	622	22	for	for	IN
cord-023443-pvz7dll9	622	23	the	the	DT
cord-023443-pvz7dll9	622	24	protease	protease	NN
cord-023443-pvz7dll9	622	25	domains	domain	NNS
cord-023443-pvz7dll9	622	26	have	have	VBP
cord-023443-pvz7dll9	622	27	to	to	TO
cord-023443-pvz7dll9	622	28	be	be	VB
cord-023443-pvz7dll9	622	29	constructed	construct	VBN
cord-023443-pvz7dll9	622	30	,	,	,
cord-023443-pvz7dll9	622	31	if	if	IN
cord-023443-pvz7dll9	622	32	one	one	PRP
cord-023443-pvz7dll9	622	33	wishes	wish	VBZ
cord-023443-pvz7dll9	622	34	to	to	TO
cord-023443-pvz7dll9	622	35	measure	measure	VB
cord-023443-pvz7dll9	622	36	the	the	DT
cord-023443-pvz7dll9	622	37	proteins	protein	NNS
cord-023443-pvz7dll9	622	38	individually	individually	RB
cord-023443-pvz7dll9	622	39	.	.	.
cord-023443-pvz7dll9	623	1	We	-PRON-	PRP
cord-023443-pvz7dll9	623	2	present	present	VBP
cord-023443-pvz7dll9	623	3	an	an	DT
cord-023443-pvz7dll9	623	4	assay	assay	NN
cord-023443-pvz7dll9	623	5	for	for	IN
cord-023443-pvz7dll9	623	6	quantifying	quantify	VBG
cord-023443-pvz7dll9	623	7	total	total	JJ
cord-023443-pvz7dll9	623	8	MASP-3	masp-3	NN
cord-023443-pvz7dll9	623	9	in	in	IN
cord-023443-pvz7dll9	623	10	plasma	plasma	NN
cord-023443-pvz7dll9	623	11	and	and	CC
cord-023443-pvz7dll9	623	12	serum	serum	NN
cord-023443-pvz7dll9	623	13	samples	sample	NNS
cord-023443-pvz7dll9	623	14	.	.	.
cord-023443-pvz7dll9	624	1	The	the	DT
cord-023443-pvz7dll9	624	2	assay	assay	NN
cord-023443-pvz7dll9	624	3	is	be	VBZ
cord-023443-pvz7dll9	624	4	a	a	DT
cord-023443-pvz7dll9	624	5	sandwich	sandwich	NN
cord-023443-pvz7dll9	624	6	-	-	HYPH
cord-023443-pvz7dll9	624	7	type	type	NN
cord-023443-pvz7dll9	624	8	assay	assay	NN
cord-023443-pvz7dll9	624	9	using	use	VBG
cord-023443-pvz7dll9	624	10	as	as	IN
cord-023443-pvz7dll9	624	11	catching	catch	VBG
cord-023443-pvz7dll9	624	12	antibody	antibody	NN
cord-023443-pvz7dll9	624	13	a	a	DT
cord-023443-pvz7dll9	624	14	monoclonal	monoclonal	JJ
cord-023443-pvz7dll9	624	15	antibody	antibody	NN
cord-023443-pvz7dll9	624	16	against	against	IN
cord-023443-pvz7dll9	624	17	the	the	DT
cord-023443-pvz7dll9	624	18	common	common	JJ
cord-023443-pvz7dll9	624	19	A	a	NN
cord-023443-pvz7dll9	624	20	-	-	HYPH
cord-023443-pvz7dll9	624	21	chain	chain	NN
cord-023443-pvz7dll9	624	22	of	of	IN
cord-023443-pvz7dll9	624	23	MASP-1/3	MASP-1/3	NNP
cord-023443-pvz7dll9	624	24	and	and	CC
cord-023443-pvz7dll9	624	25	a	a	DT
cord-023443-pvz7dll9	624	26	developing	develop	VBG
cord-023443-pvz7dll9	624	27	secondary	secondary	JJ
cord-023443-pvz7dll9	624	28	antibody	antibody	NN
cord-023443-pvz7dll9	624	29	against	against	IN
cord-023443-pvz7dll9	624	30	the	the	DT
cord-023443-pvz7dll9	624	31	C	C	NNP
cord-023443-pvz7dll9	624	32	-	-	HYPH
cord-023443-pvz7dll9	624	33	terminal	terminal	NN
cord-023443-pvz7dll9	624	34	part	part	NN
cord-023443-pvz7dll9	624	35	of	of	IN
cord-023443-pvz7dll9	624	36	the	the	DT
cord-023443-pvz7dll9	624	37	protease	protease	NN
cord-023443-pvz7dll9	624	38	domain	domain	NN
cord-023443-pvz7dll9	624	39	of	of	IN
cord-023443-pvz7dll9	624	40	MASP-3	MASP-3	NNP
cord-023443-pvz7dll9	624	41	.	.	.
cord-023443-pvz7dll9	625	1	We	-PRON-	PRP
cord-023443-pvz7dll9	625	2	have	have	VBP
cord-023443-pvz7dll9	625	3	used	use	VBN
cord-023443-pvz7dll9	625	4	this	this	DT
cord-023443-pvz7dll9	625	5	assay	assay	NN
cord-023443-pvz7dll9	625	6	for	for	IN
cord-023443-pvz7dll9	625	7	estimating	estimate	VBG
cord-023443-pvz7dll9	625	8	the	the	DT
cord-023443-pvz7dll9	625	9	normal	normal	JJ
cord-023443-pvz7dll9	625	10	concentration	concentration	NN
cord-023443-pvz7dll9	625	11	of	of	IN
cord-023443-pvz7dll9	625	12	the	the	DT
cord-023443-pvz7dll9	625	13	protein	protein	NN
cord-023443-pvz7dll9	625	14	as	as	RB
cord-023443-pvz7dll9	625	15	well	well	RB
cord-023443-pvz7dll9	625	16	as	as	IN
cord-023443-pvz7dll9	625	17	the	the	DT
cord-023443-pvz7dll9	625	18	concentration	concentration	NN
cord-023443-pvz7dll9	625	19	in	in	IN
cord-023443-pvz7dll9	625	20	patients	patient	NNS
cord-023443-pvz7dll9	625	21	and	and	CC
cord-023443-pvz7dll9	625	22	also	also	RB
cord-023443-pvz7dll9	625	23	for	for	IN
cord-023443-pvz7dll9	625	24	characterizing	characterize	VBG
cord-023443-pvz7dll9	625	25	by	by	IN
cord-023443-pvz7dll9	625	26	gel	gel	NN
cord-023443-pvz7dll9	625	27	permeation	permeation	NN
cord-023443-pvz7dll9	625	28	chromatography	chromatography	NN
cord-023443-pvz7dll9	625	29	the	the	DT
cord-023443-pvz7dll9	625	30	MASP-3	MASP-3	NNP
cord-023443-pvz7dll9	625	31	protein	protein	NN
cord-023443-pvz7dll9	625	32	in	in	IN
cord-023443-pvz7dll9	625	33	serum	serum	NN
cord-023443-pvz7dll9	625	34	.	.	.
cord-023443-pvz7dll9	626	1	Inducible	inducible	JJ
cord-023443-pvz7dll9	626	2	costimulator	costimulator	NN
cord-023443-pvz7dll9	626	3	ligand	ligand	NN
cord-023443-pvz7dll9	626	4	(	(	-LRB-
cord-023443-pvz7dll9	626	5	ICOSL	ICOSL	NNP
cord-023443-pvz7dll9	626	6	)	)	-RRB-
cord-023443-pvz7dll9	626	7	is	be	VBZ
cord-023443-pvz7dll9	626	8	a	a	DT
cord-023443-pvz7dll9	626	9	costimulatory	costimulatory	NN
cord-023443-pvz7dll9	626	10	molecule	molecule	NN
cord-023443-pvz7dll9	626	11	related	relate	VBN
cord-023443-pvz7dll9	626	12	to	to	IN
cord-023443-pvz7dll9	626	13	B7.1	B7.1	NNP
cord-023443-pvz7dll9	626	14	(	(	-LRB-
cord-023443-pvz7dll9	626	15	CD80	CD80	NNP
cord-023443-pvz7dll9	626	16	)	)	-RRB-
cord-023443-pvz7dll9	626	17	and	and	CC
cord-023443-pvz7dll9	626	18	B7.2	B7.2	NNP
cord-023443-pvz7dll9	626	19	(	(	-LRB-
cord-023443-pvz7dll9	626	20	CD86	CD86	NNP
cord-023443-pvz7dll9	626	21	)	)	-RRB-
cord-023443-pvz7dll9	626	22	.	.	.
cord-023443-pvz7dll9	627	1	B	b	NN
cord-023443-pvz7dll9	627	2	cells	cell	NNS
cord-023443-pvz7dll9	627	3	,	,	,
cord-023443-pvz7dll9	627	4	monocytes	monocyte	NNS
cord-023443-pvz7dll9	627	5	,	,	,
cord-023443-pvz7dll9	627	6	dendritic	dendritic	JJ
cord-023443-pvz7dll9	627	7	cells	cell	NNS
cord-023443-pvz7dll9	627	8	and	and	CC
cord-023443-pvz7dll9	627	9	endothelial	endothelial	JJ
cord-023443-pvz7dll9	627	10	cells	cell	NNS
cord-023443-pvz7dll9	627	11	express	express	VBP
cord-023443-pvz7dll9	627	12	ICOSL	ICOSL	NNP
cord-023443-pvz7dll9	627	13	.	.	.
cord-023443-pvz7dll9	628	1	Inducible	inducible	JJ
cord-023443-pvz7dll9	628	2	costimulator	costimulator	NN
cord-023443-pvz7dll9	628	3	(	(	-LRB-
cord-023443-pvz7dll9	628	4	ICOS	ICOS	NNP
cord-023443-pvz7dll9	628	5	)	)	-RRB-
cord-023443-pvz7dll9	628	6	interacts	interact	VBZ
cord-023443-pvz7dll9	628	7	with	with	IN
cord-023443-pvz7dll9	628	8	ICOSL	ICOSL	NNP
cord-023443-pvz7dll9	628	9	,	,	,
cord-023443-pvz7dll9	628	10	and	and	CC
cord-023443-pvz7dll9	628	11	this	this	DT
cord-023443-pvz7dll9	628	12	interaction	interaction	NN
cord-023443-pvz7dll9	628	13	leads	lead	VBZ
cord-023443-pvz7dll9	628	14	to	to	IN
cord-023443-pvz7dll9	628	15	signals	signal	NNS
cord-023443-pvz7dll9	628	16	involved	involve	VBN
cord-023443-pvz7dll9	628	17	in	in	IN
cord-023443-pvz7dll9	628	18	isotype	isotype	NN
cord-023443-pvz7dll9	628	19	switching	switch	VBG
cord-023443-pvz7dll9	628	20	and	and	CC
cord-023443-pvz7dll9	628	21	the	the	DT
cord-023443-pvz7dll9	628	22	development	development	NN
cord-023443-pvz7dll9	628	23	of	of	IN
cord-023443-pvz7dll9	628	24	immunological	immunological	JJ
cord-023443-pvz7dll9	628	25	memory	memory	NN
cord-023443-pvz7dll9	628	26	.	.	.
cord-023443-pvz7dll9	629	1	Hitherto	Hitherto	VBN
cord-023443-pvz7dll9	629	2	,	,	,
cord-023443-pvz7dll9	629	3	no	no	DT
cord-023443-pvz7dll9	629	4	polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	629	5	of	of	IN
cord-023443-pvz7dll9	629	6	this	this	DT
cord-023443-pvz7dll9	629	7	gene	gene	NN
cord-023443-pvz7dll9	629	8	have	have	VBP
cord-023443-pvz7dll9	629	9	been	be	VBN
cord-023443-pvz7dll9	629	10	described	describe	VBN
cord-023443-pvz7dll9	629	11	.	.	.
cord-023443-pvz7dll9	630	1	The	the	DT
cord-023443-pvz7dll9	630	2	aim	aim	NN
cord-023443-pvz7dll9	630	3	of	of	IN
cord-023443-pvz7dll9	630	4	this	this	DT
cord-023443-pvz7dll9	630	5	study	study	NN
cord-023443-pvz7dll9	630	6	was	be	VBD
cord-023443-pvz7dll9	630	7	to	to	TO
cord-023443-pvz7dll9	630	8	reveal	reveal	VB
cord-023443-pvz7dll9	630	9	variation	variation	NN
cord-023443-pvz7dll9	630	10	of	of	IN
cord-023443-pvz7dll9	630	11	the	the	DT
cord-023443-pvz7dll9	630	12	ICOSL	ICOSL	NNP
cord-023443-pvz7dll9	630	13	gene	gene	NN
cord-023443-pvz7dll9	630	14	in	in	IN
cord-023443-pvz7dll9	630	15	normal	normal	JJ
cord-023443-pvz7dll9	630	16	individuals	individual	NNS
cord-023443-pvz7dll9	630	17	.	.	.
cord-023443-pvz7dll9	631	1	All	all	DT
cord-023443-pvz7dll9	631	2	eight	eight	CD
cord-023443-pvz7dll9	631	3	exons	exon	NNS
cord-023443-pvz7dll9	631	4	,	,	,
cord-023443-pvz7dll9	631	5	except	except	IN
cord-023443-pvz7dll9	631	6	exon	exon	NN
cord-023443-pvz7dll9	631	7	1	1	CD
cord-023443-pvz7dll9	631	8	,	,	,
cord-023443-pvz7dll9	631	9	were	be	VBD
cord-023443-pvz7dll9	631	10	sequenced	sequence	VBN
cord-023443-pvz7dll9	631	11	with	with	IN
cord-023443-pvz7dll9	631	12	flanking	flank	VBG
cord-023443-pvz7dll9	631	13	introns	intron	NNS
cord-023443-pvz7dll9	631	14	in	in	IN
cord-023443-pvz7dll9	631	15	10	10	CD
cord-023443-pvz7dll9	631	16	healthy	healthy	JJ
cord-023443-pvz7dll9	631	17	blood	blood	NN
cord-023443-pvz7dll9	631	18	donors	donor	NNS
cord-023443-pvz7dll9	631	19	.	.	.
cord-023443-pvz7dll9	632	1	Eight	eight	CD
cord-023443-pvz7dll9	632	2	single	single	JJ
cord-023443-pvz7dll9	632	3	nucleotide	nucleotide	JJ
cord-023443-pvz7dll9	632	4	polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	632	5	(	(	-LRB-
cord-023443-pvz7dll9	632	6	SNPs	SNPs	NNP
cord-023443-pvz7dll9	632	7	)	)	-RRB-
cord-023443-pvz7dll9	632	8	and	and	CC
cord-023443-pvz7dll9	632	9	two	two	CD
cord-023443-pvz7dll9	632	10	length	length	NN
cord-023443-pvz7dll9	632	11	polymorphisms	polymorphism	NNS
cord-023443-pvz7dll9	632	12	were	be	VBD
cord-023443-pvz7dll9	632	13	found	find	VBN
cord-023443-pvz7dll9	632	14	.	.	.
cord-023443-pvz7dll9	633	1	One	one	CD
cord-023443-pvz7dll9	633	2	of	of	IN
cord-023443-pvz7dll9	633	3	the	the	DT
cord-023443-pvz7dll9	633	4	SNPs	snp	NNS
cord-023443-pvz7dll9	633	5	was	be	VBD
cord-023443-pvz7dll9	633	6	found	find	VBN
cord-023443-pvz7dll9	633	7	in	in	IN
cord-023443-pvz7dll9	633	8	the	the	DT
cord-023443-pvz7dll9	633	9	coding	code	VBG
cord-023443-pvz7dll9	633	10	regions	region	NNS
cord-023443-pvz7dll9	633	11	of	of	IN
cord-023443-pvz7dll9	633	12	the	the	DT
cord-023443-pvz7dll9	633	13	gene	gene	NN
cord-023443-pvz7dll9	633	14	.	.	.
cord-023443-pvz7dll9	634	1	The	the	DT
cord-023443-pvz7dll9	634	2	base	base	NN
cord-023443-pvz7dll9	634	3	involved	involve	VBN
cord-023443-pvz7dll9	634	4	was	be	VBD
cord-023443-pvz7dll9	634	5	located	locate	VBN
cord-023443-pvz7dll9	634	6	in	in	IN
cord-023443-pvz7dll9	634	7	exon	exon	NN
cord-023443-pvz7dll9	634	8	3	3	CD
cord-023443-pvz7dll9	634	9	and	and	CC
cord-023443-pvz7dll9	634	10	caused	cause	VBD
cord-023443-pvz7dll9	634	11	a	a	DT
cord-023443-pvz7dll9	634	12	conservative	conservative	JJ
cord-023443-pvz7dll9	634	13	amino	amino	NN
cord-023443-pvz7dll9	634	14	acid	acid	NN
cord-023443-pvz7dll9	634	15	change	change	NN
cord-023443-pvz7dll9	634	16	from	from	IN
cord-023443-pvz7dll9	634	17	valine	valine	NN
cord-023443-pvz7dll9	634	18	(	(	-LRB-
cord-023443-pvz7dll9	634	19	GTT	GTT	NNP
cord-023443-pvz7dll9	634	20	)	)	-RRB-
cord-023443-pvz7dll9	634	21	to	to	IN
cord-023443-pvz7dll9	634	22	isoleucine	isoleucine	NNP
cord-023443-pvz7dll9	634	23	(	(	-LRB-
cord-023443-pvz7dll9	634	24	ATT	ATT	NNP
cord-023443-pvz7dll9	634	25	)	)	-RRB-
cord-023443-pvz7dll9	634	26	.	.	.
cord-023443-pvz7dll9	635	1	Three	three	CD
cord-023443-pvz7dll9	635	2	individuals	individual	NNS
cord-023443-pvz7dll9	635	3	were	be	VBD
cord-023443-pvz7dll9	635	4	heterozygous	heterozygous	JJ
cord-023443-pvz7dll9	635	5	G	G	NNP
cord-023443-pvz7dll9	635	6	/	/	SYM
cord-023443-pvz7dll9	635	7	A	a	NN
cord-023443-pvz7dll9	635	8	for	for	IN
cord-023443-pvz7dll9	635	9	the	the	DT
cord-023443-pvz7dll9	635	10	exon	exon	NN
cord-023443-pvz7dll9	635	11	polymorphism	polymorphism	NN
cord-023443-pvz7dll9	635	12	,	,	,
cord-023443-pvz7dll9	635	13	while	while	IN
cord-023443-pvz7dll9	635	14	the	the	DT
cord-023443-pvz7dll9	635	15	remaining	remain	VBG
cord-023443-pvz7dll9	635	16	seven	seven	CD
cord-023443-pvz7dll9	635	17	individuals	individual	NNS
cord-023443-pvz7dll9	635	18	were	be	VBD
cord-023443-pvz7dll9	635	19	homozygous	homozygous	JJ
cord-023443-pvz7dll9	635	20	for	for	IN
cord-023443-pvz7dll9	636	1	the	the	DT
cord-023443-pvz7dll9	636	2	wildtype	wildtype	JJ
cord-023443-pvz7dll9	636	3	G	G	NNP
cord-023443-pvz7dll9	636	4	/	/	SYM
cord-023443-pvz7dll9	636	5	G.	G.	NNP
cord-023443-pvz7dll9	636	6	Exon	Exon	NNP
cord-023443-pvz7dll9	636	7	3	3	CD
cord-023443-pvz7dll9	636	8	encodes	encode	VBZ
cord-023443-pvz7dll9	636	9	the	the	DT
cord-023443-pvz7dll9	636	10	immunoglobulin	immunoglobulin	NN
cord-023443-pvz7dll9	636	11	variable	variable	NN
cord-023443-pvz7dll9	636	12	(	(	-LRB-
cord-023443-pvz7dll9	636	13	IgV)-like	IgV)-like	NNP
cord-023443-pvz7dll9	636	14	domain	domain	NN
cord-023443-pvz7dll9	636	15	of	of	IN
cord-023443-pvz7dll9	636	16	the	the	DT
cord-023443-pvz7dll9	636	17	molecule	molecule	NN
cord-023443-pvz7dll9	636	18	which	which	WDT
cord-023443-pvz7dll9	636	19	is	be	VBZ
cord-023443-pvz7dll9	636	20	situated	situate	VBN
cord-023443-pvz7dll9	636	21	outside	outside	IN
cord-023443-pvz7dll9	636	22	the	the	DT
cord-023443-pvz7dll9	636	23	cell	cell	NN
cord-023443-pvz7dll9	636	24	.	.	.
cord-023443-pvz7dll9	637	1	This	this	DT
cord-023443-pvz7dll9	637	2	means	mean	VBZ
cord-023443-pvz7dll9	637	3	that	that	IN
cord-023443-pvz7dll9	637	4	the	the	DT
cord-023443-pvz7dll9	637	5	amino	amino	NN
cord-023443-pvz7dll9	637	6	acid	acid	NN
cord-023443-pvz7dll9	637	7	could	could	MD
cord-023443-pvz7dll9	637	8	be	be	VB
cord-023443-pvz7dll9	637	9	critical	critical	JJ
cord-023443-pvz7dll9	637	10	for	for	IN
cord-023443-pvz7dll9	637	11	the	the	DT
cord-023443-pvz7dll9	637	12	stability	stability	NN
cord-023443-pvz7dll9	637	13	of	of	IN
cord-023443-pvz7dll9	637	14	the	the	DT
cord-023443-pvz7dll9	637	15	molecule	molecule	NN
cord-023443-pvz7dll9	637	16	or	or	CC
cord-023443-pvz7dll9	637	17	could	could	MD
cord-023443-pvz7dll9	637	18	constitute	constitute	VB
cord-023443-pvz7dll9	637	19	part	part	NN
cord-023443-pvz7dll9	637	20	of	of	IN
cord-023443-pvz7dll9	637	21	the	the	DT
cord-023443-pvz7dll9	637	22	binding	binding	NN
cord-023443-pvz7dll9	637	23	site	site	NN
cord-023443-pvz7dll9	637	24	for	for	IN
cord-023443-pvz7dll9	637	25	ICOS	ICOS	NNP
cord-023443-pvz7dll9	637	26	.	.	.
cord-023443-pvz7dll9	638	1	The	the	DT
cord-023443-pvz7dll9	638	2	results	result	NNS
cord-023443-pvz7dll9	638	3	form	form	VBP
cord-023443-pvz7dll9	638	4	the	the	DT
cord-023443-pvz7dll9	638	5	basis	basis	NN
cord-023443-pvz7dll9	638	6	for	for	IN
cord-023443-pvz7dll9	638	7	further	further	JJ
cord-023443-pvz7dll9	638	8	experiments	experiment	NNS
cord-023443-pvz7dll9	638	9	to	to	TO
cord-023443-pvz7dll9	638	10	find	find	VB
cord-023443-pvz7dll9	638	11	possible	possible	JJ
cord-023443-pvz7dll9	638	12	associations	association	NNS
cord-023443-pvz7dll9	638	13	of	of	IN
cord-023443-pvz7dll9	638	14	the	the	DT
cord-023443-pvz7dll9	638	15	alleles	allele	NNS
cord-023443-pvz7dll9	638	16	to	to	IN
cord-023443-pvz7dll9	638	17	diseases	disease	NNS
cord-023443-pvz7dll9	638	18	caused	cause	VBN
cord-023443-pvz7dll9	638	19	by	by	IN
cord-023443-pvz7dll9	638	20	immune	immune	JJ
cord-023443-pvz7dll9	638	21	dysregulation	dysregulation	NN
cord-023443-pvz7dll9	638	22	.	.	.
cord-023443-pvz7dll9	639	1	Especially	especially	RB
cord-023443-pvz7dll9	639	2	,	,	,
cord-023443-pvz7dll9	639	3	the	the	DT
cord-023443-pvz7dll9	639	4	exon	exon	NN
cord-023443-pvz7dll9	639	5	3	3	CD
cord-023443-pvz7dll9	639	6	variant	variant	NN
cord-023443-pvz7dll9	639	7	is	be	VBZ
cord-023443-pvz7dll9	639	8	interesting	interesting	JJ
cord-023443-pvz7dll9	639	9	and	and	CC
cord-023443-pvz7dll9	639	10	could	could	MD
cord-023443-pvz7dll9	639	11	play	play	VB
cord-023443-pvz7dll9	639	12	a	a	DT
cord-023443-pvz7dll9	639	13	role	role	NN
cord-023443-pvz7dll9	639	14	for	for	IN
cord-023443-pvz7dll9	639	15	the	the	DT
cord-023443-pvz7dll9	639	16	development	development	NN
cord-023443-pvz7dll9	639	17	of	of	IN
cord-023443-pvz7dll9	639	18	immunological	immunological	JJ
cord-023443-pvz7dll9	639	19	diseases	disease	NNS
cord-023443-pvz7dll9	639	20	.	.	.
cord-023443-pvz7dll9	640	1	Besides	besides	RB
cord-023443-pvz7dll9	640	2	,	,	,
cord-023443-pvz7dll9	640	3	it	-PRON-	PRP
cord-023443-pvz7dll9	640	4	would	would	MD
cord-023443-pvz7dll9	640	5	be	be	VB
cord-023443-pvz7dll9	640	6	interesting	interesting	JJ
cord-023443-pvz7dll9	640	7	to	to	TO
cord-023443-pvz7dll9	640	8	see	see	VB
cord-023443-pvz7dll9	640	9	whether	whether	IN
cord-023443-pvz7dll9	640	10	both	both	DT
cord-023443-pvz7dll9	640	11	exon	exon	NN
cord-023443-pvz7dll9	640	12	3	3	CD
cord-023443-pvz7dll9	640	13	alleles	allele	NNS
cord-023443-pvz7dll9	640	14	are	be	VBP
cord-023443-pvz7dll9	640	15	expressed	express	VBN
cord-023443-pvz7dll9	640	16	or	or	CC
cord-023443-pvz7dll9	640	17	only	only	RB
cord-023443-pvz7dll9	640	18	the	the	DT
cord-023443-pvz7dll9	640	19	wildtype	wildtype	JJ
cord-023443-pvz7dll9	640	20	allele	allele	NN
cord-023443-pvz7dll9	640	21	is	be	VBZ
cord-023443-pvz7dll9	640	22	functional	functional	JJ
cord-023443-pvz7dll9	640	23	.	.	.
cord-023443-pvz7dll9	641	1	Interferon	interferon	NN
cord-023443-pvz7dll9	641	2	-	-	HYPH
cord-023443-pvz7dll9	641	3	a	a	NN
cord-023443-pvz7dll9	641	4	/	/	SYM
cord-023443-pvz7dll9	641	5	b	b	NN
cord-023443-pvz7dll9	641	6	(	(	-LRB-
cord-023443-pvz7dll9	641	7	IFN	IFN	NNP
cord-023443-pvz7dll9	641	8	-	-	HYPH
cord-023443-pvz7dll9	641	9	a	a	NNP
cord-023443-pvz7dll9	641	10	/	/	SYM
cord-023443-pvz7dll9	641	11	b	b	NN
cord-023443-pvz7dll9	641	12	)	)	-RRB-
cord-023443-pvz7dll9	641	13	is	be	VBZ
cord-023443-pvz7dll9	641	14	increasingly	increasingly	RB
cord-023443-pvz7dll9	641	15	used	use	VBN
cord-023443-pvz7dll9	641	16	as	as	IN
cord-023443-pvz7dll9	641	17	antiviral	antiviral	JJ
cord-023443-pvz7dll9	641	18	and	and	CC
cord-023443-pvz7dll9	641	19	immunomodulatory	immunomodulatory	JJ
cord-023443-pvz7dll9	641	20	therapies	therapy	NNS
cord-023443-pvz7dll9	641	21	.	.	.
cord-023443-pvz7dll9	642	1	Unfortunately	unfortunately	RB
cord-023443-pvz7dll9	642	2	,	,	,
cord-023443-pvz7dll9	642	3	bioavailability	bioavailability	NN
cord-023443-pvz7dll9	642	4	varies	vary	VBZ
cord-023443-pvz7dll9	642	5	with	with	IN
cord-023443-pvz7dll9	642	6	IFN	IFN	NNP
cord-023443-pvz7dll9	642	7	species	specie	NNS
cord-023443-pvz7dll9	642	8	and	and	CC
cord-023443-pvz7dll9	642	9	mode	mode	NN
cord-023443-pvz7dll9	642	10	of	of	IN
cord-023443-pvz7dll9	642	11	administration	administration	NN
cord-023443-pvz7dll9	642	12	,	,	,
cord-023443-pvz7dll9	642	13	and	and	CC
cord-023443-pvz7dll9	642	14	all	all	DT
cord-023443-pvz7dll9	642	15	IFN	IFN	NNP
cord-023443-pvz7dll9	642	16	species	specie	NNS
cord-023443-pvz7dll9	642	17	are	be	VBP
cord-023443-pvz7dll9	642	18	potentially	potentially	RB
cord-023443-pvz7dll9	642	19	immunogenic	immunogenic	JJ
cord-023443-pvz7dll9	642	20	.	.	.
cord-023443-pvz7dll9	643	1	Assays	assay	NNS
cord-023443-pvz7dll9	643	2	for	for	IN
cord-023443-pvz7dll9	643	3	antiviral	antiviral	JJ
cord-023443-pvz7dll9	643	4	activity	activity	NN
cord-023443-pvz7dll9	643	5	(	(	-LRB-
cord-023443-pvz7dll9	643	6	IFN	IFN	NNP
cord-023443-pvz7dll9	643	7	)	)	-RRB-
cord-023443-pvz7dll9	643	8	and	and	CC
cord-023443-pvz7dll9	643	9	antiviral	antiviral	JJ
cord-023443-pvz7dll9	643	10	neutralization	neutralization	NN
cord-023443-pvz7dll9	643	11	(	(	-LRB-
cord-023443-pvz7dll9	643	12	antibodies	antibody	NNS
cord-023443-pvz7dll9	643	13	,	,	,
cord-023443-pvz7dll9	643	14	NAb	NAb	NNS
cord-023443-pvz7dll9	643	15	)	)	-RRB-
cord-023443-pvz7dll9	643	16	have	have	VBP
cord-023443-pvz7dll9	643	17	been	be	VBN
cord-023443-pvz7dll9	643	18	used	use	VBN
cord-023443-pvz7dll9	643	19	for	for	IN
cord-023443-pvz7dll9	643	20	some	some	DT
cord-023443-pvz7dll9	643	21	time	time	NN
cord-023443-pvz7dll9	643	22	to	to	TO
cord-023443-pvz7dll9	643	23	monitor	monitor	VB
cord-023443-pvz7dll9	643	24	patients	patient	NNS
cord-023443-pvz7dll9	643	25	on	on	IN
cord-023443-pvz7dll9	643	26	IFN	IFN	NNP
cord-023443-pvz7dll9	643	27	biologicals	biological	NNS
cord-023443-pvz7dll9	643	28	.	.	.
cord-023443-pvz7dll9	644	1	These	these	DT
cord-023443-pvz7dll9	644	2	assays	assay	NNS
cord-023443-pvz7dll9	644	3	require	require	VBP
cord-023443-pvz7dll9	644	4	laborious	laborious	JJ
cord-023443-pvz7dll9	644	5	titrations	titration	NNS
cord-023443-pvz7dll9	644	6	making	make	VBG
cord-023443-pvz7dll9	644	7	them	-PRON-	PRP
cord-023443-pvz7dll9	644	8	unsuitable	unsuitable	JJ
cord-023443-pvz7dll9	644	9	for	for	IN
cord-023443-pvz7dll9	644	10	large	large	JJ
cord-023443-pvz7dll9	644	11	-	-	HYPH
cord-023443-pvz7dll9	644	12	scale	scale	NN
cord-023443-pvz7dll9	644	13	clinical	clinical	JJ
cord-023443-pvz7dll9	644	14	use	use	NN
cord-023443-pvz7dll9	644	15	.	.	.
cord-023443-pvz7dll9	645	1	Myxovirus	Myxovirus	NNP
cord-023443-pvz7dll9	645	2	A	A	NNP
cord-023443-pvz7dll9	645	3	(	(	-LRB-
cord-023443-pvz7dll9	645	4	MxA	mxa	NN
cord-023443-pvz7dll9	645	5	)	)	-RRB-
cord-023443-pvz7dll9	645	6	is	be	VBZ
cord-023443-pvz7dll9	645	7	a	a	DT
cord-023443-pvz7dll9	645	8	resistance	resistance	NN
cord-023443-pvz7dll9	645	9	GTPbinding	gtpbinding	NN
cord-023443-pvz7dll9	645	10	protein	protein	NN
cord-023443-pvz7dll9	645	11	that	that	WDT
cord-023443-pvz7dll9	645	12	is	be	VBZ
cord-023443-pvz7dll9	645	13	specifically	specifically	RB
cord-023443-pvz7dll9	645	14	induced	induce	VBN
cord-023443-pvz7dll9	645	15	by	by	IN
cord-023443-pvz7dll9	645	16	treatment	treatment	NN
cord-023443-pvz7dll9	645	17	with	with	IN
cord-023443-pvz7dll9	645	18	type	type	NN
cord-023443-pvz7dll9	645	19	1	1	CD
cord-023443-pvz7dll9	645	20	IFNs	ifn	NNS
cord-023443-pvz7dll9	645	21	.	.	.
cord-023443-pvz7dll9	646	1	For	for	IN
cord-023443-pvz7dll9	646	2	example	example	NN
cord-023443-pvz7dll9	646	3	,	,	,
cord-023443-pvz7dll9	646	4	IFN	IFN	NNP
cord-023443-pvz7dll9	646	5	-	-	HYPH
cord-023443-pvz7dll9	646	6	b	b	NNP
cord-023443-pvz7dll9	646	7	-	-	HYPH
cord-023443-pvz7dll9	646	8	induced	induce	VBN
cord-023443-pvz7dll9	646	9	MxA	mxa	NN
cord-023443-pvz7dll9	646	10	in	in	IN
cord-023443-pvz7dll9	646	11	blood	blood	NN
cord-023443-pvz7dll9	646	12	leucocytes	leucocyte	NNS
cord-023443-pvz7dll9	646	13	has	have	VBZ
cord-023443-pvz7dll9	646	14	been	be	VBN
cord-023443-pvz7dll9	646	15	used	use	VBN
cord-023443-pvz7dll9	646	16	as	as	IN
cord-023443-pvz7dll9	646	17	a	a	DT
cord-023443-pvz7dll9	646	18	biomarker	biomarker	NN
cord-023443-pvz7dll9	646	19	in	in	IN
cord-023443-pvz7dll9	646	20	IFN	IFN	NNP
cord-023443-pvz7dll9	646	21	-	-	HYPH
cord-023443-pvz7dll9	646	22	btreated	btreate	VBN
cord-023443-pvz7dll9	646	23	patients	patient	NNS
cord-023443-pvz7dll9	646	24	with	with	IN
cord-023443-pvz7dll9	646	25	multiple	multiple	JJ
cord-023443-pvz7dll9	646	26	sclerosis	sclerosis	NN
cord-023443-pvz7dll9	646	27	.	.	.
cord-023443-pvz7dll9	647	1	However	however	RB
cord-023443-pvz7dll9	647	2	,	,	,
cord-023443-pvz7dll9	647	3	the	the	DT
cord-023443-pvz7dll9	647	4	degree	degree	NN
cord-023443-pvz7dll9	647	5	of	of	IN
cord-023443-pvz7dll9	647	6	specificity	specificity	NN
cord-023443-pvz7dll9	647	7	of	of	IN
cord-023443-pvz7dll9	647	8	MxA	mxa	NN
cord-023443-pvz7dll9	647	9	in	in	IN
cord-023443-pvz7dll9	647	10	this	this	DT
cord-023443-pvz7dll9	647	11	regard	regard	NN
cord-023443-pvz7dll9	647	12	is	be	VBZ
cord-023443-pvz7dll9	647	13	unclear	unclear	JJ
cord-023443-pvz7dll9	647	14	,	,	,
cord-023443-pvz7dll9	647	15	and	and	CC
cord-023443-pvz7dll9	647	16	measurements	measurement	NNS
cord-023443-pvz7dll9	647	17	of	of	IN
cord-023443-pvz7dll9	647	18	MxA	mxa	NN
cord-023443-pvz7dll9	647	19	protein	protein	NN
cord-023443-pvz7dll9	647	20	and/or	and/or	CC
cord-023443-pvz7dll9	648	1	mRNA	mrna	NN
cord-023443-pvz7dll9	648	2	are	be	VBP
cord-023443-pvz7dll9	648	3	not	not	RB
cord-023443-pvz7dll9	648	4	yet	yet	RB
cord-023443-pvz7dll9	648	5	suitable	suitable	JJ
cord-023443-pvz7dll9	648	6	for	for	IN
cord-023443-pvz7dll9	648	7	routine	routine	JJ
cord-023443-pvz7dll9	648	8	clinical	clinical	JJ
cord-023443-pvz7dll9	648	9	use	use	NN
cord-023443-pvz7dll9	648	10	.	.	.
cord-023443-pvz7dll9	649	1	In	in	IN
cord-023443-pvz7dll9	649	2	an	an	DT
cord-023443-pvz7dll9	649	3	attempt	attempt	NN
cord-023443-pvz7dll9	649	4	to	to	TO
cord-023443-pvz7dll9	649	5	find	find	VB
cord-023443-pvz7dll9	649	6	new	new	JJ
cord-023443-pvz7dll9	649	7	and	and	CC
cord-023443-pvz7dll9	649	8	better	well	JJR
cord-023443-pvz7dll9	649	9	reporter	reporter	NN
cord-023443-pvz7dll9	649	10	genes	gene	NNS
cord-023443-pvz7dll9	649	11	(	(	-LRB-
cord-023443-pvz7dll9	649	12	and	and	CC
cord-023443-pvz7dll9	649	13	,	,	,
cord-023443-pvz7dll9	649	14	hopefully	hopefully	RB
cord-023443-pvz7dll9	649	15	,	,	,
cord-023443-pvz7dll9	649	16	genes	gene	NNS
cord-023443-pvz7dll9	649	17	and	and	CC
cord-023443-pvz7dll9	649	18	gene	gene	NN
cord-023443-pvz7dll9	649	19	products	product	NNS
cord-023443-pvz7dll9	649	20	with	with	IN
cord-023443-pvz7dll9	649	21	proven	prove	VBN
cord-023443-pvz7dll9	649	22	specificity	specificity	NN
cord-023443-pvz7dll9	649	23	for	for	IN
cord-023443-pvz7dll9	649	24	IFN	IFN	NNP
cord-023443-pvz7dll9	649	25	-	-	:
cord-023443-pvz7dll9	649	26	a	a	NN
cord-023443-pvz7dll9	649	27	and	and	CC
cord-023443-pvz7dll9	649	28	-b	-b	SYM
cord-023443-pvz7dll9	649	29	)	)	-RRB-
cord-023443-pvz7dll9	649	30	,	,	,
cord-023443-pvz7dll9	649	31	microarray	microarray	NN
cord-023443-pvz7dll9	649	32	screenings	screening	NNS
cord-023443-pvz7dll9	649	33	with	with	IN
cord-023443-pvz7dll9	649	34	U133A	U133A	NNP
cord-023443-pvz7dll9	649	35	GeneChips	GeneChips	NNP
cord-023443-pvz7dll9	649	36	(	(	-LRB-
cord-023443-pvz7dll9	649	37	Affymetrix	Affymetrix	NNP
cord-023443-pvz7dll9	649	38	)	)	-RRB-
cord-023443-pvz7dll9	649	39	were	be	VBD
cord-023443-pvz7dll9	649	40	carried	carry	VBN
cord-023443-pvz7dll9	649	41	using	use	VBG
cord-023443-pvz7dll9	649	42	human	human	JJ
cord-023443-pvz7dll9	649	43	blood	blood	NN
cord-023443-pvz7dll9	649	44	leucocytes	leucocyte	NNS
cord-023443-pvz7dll9	649	45	and	and	CC
cord-023443-pvz7dll9	649	46	the	the	DT
cord-023443-pvz7dll9	649	47	human	human	JJ
cord-023443-pvz7dll9	649	48	lung	lung	NN
cord-023443-pvz7dll9	649	49	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	649	50	cell	cell	NN
cord-023443-pvz7dll9	649	51	line	line	NN
cord-023443-pvz7dll9	649	52	A549	a549	JJ
cord-023443-pvz7dll9	649	53	.	.	.
cord-023443-pvz7dll9	650	1	We	-PRON-	PRP
cord-023443-pvz7dll9	650	2	studied	study	VBD
cord-023443-pvz7dll9	650	3	the	the	DT
cord-023443-pvz7dll9	650	4	simultaneous	simultaneous	JJ
cord-023443-pvz7dll9	650	5	expression	expression	NN
cord-023443-pvz7dll9	650	6	of	of	IN
cord-023443-pvz7dll9	650	7	22,000	22,000	CD
cord-023443-pvz7dll9	650	8	transcripts	transcript	NNS
cord-023443-pvz7dll9	650	9	before	before	IN
cord-023443-pvz7dll9	650	10	and	and	CC
cord-023443-pvz7dll9	650	11	after	after	IN
cord-023443-pvz7dll9	650	12	exposure	exposure	NN
cord-023443-pvz7dll9	650	13	to	to	IN
cord-023443-pvz7dll9	650	14	human	human	JJ
cord-023443-pvz7dll9	650	15	recombinant	recombinant	JJ
cord-023443-pvz7dll9	650	16	IFN	IFN	NNP
cord-023443-pvz7dll9	650	17	-	-	HYPH
cord-023443-pvz7dll9	650	18	a	a	NNP
cord-023443-pvz7dll9	650	19	and	and	CC
cord-023443-pvz7dll9	650	20	IFN	IFN	NNP
cord-023443-pvz7dll9	650	21	-	-	HYPH
cord-023443-pvz7dll9	650	22	b	b	NNP
cord-023443-pvz7dll9	650	23	and	and	CC
cord-023443-pvz7dll9	650	24	other	other	JJ
cord-023443-pvz7dll9	650	25	antiviral	antiviral	JJ
cord-023443-pvz7dll9	650	26	and	and	CC
cord-023443-pvz7dll9	650	27	immunomodulatory	immunomodulatory	JJ
cord-023443-pvz7dll9	650	28	cytokines	cytokine	NNS
cord-023443-pvz7dll9	650	29	.	.	.
cord-023443-pvz7dll9	651	1	The	the	DT
cord-023443-pvz7dll9	651	2	results	result	NNS
cord-023443-pvz7dll9	651	3	will	will	MD
cord-023443-pvz7dll9	651	4	be	be	VB
cord-023443-pvz7dll9	651	5	presented	present	VBN
cord-023443-pvz7dll9	651	6	at	at	IN
cord-023443-pvz7dll9	651	7	the	the	DT
cord-023443-pvz7dll9	651	8	conference	conference	NN
cord-023443-pvz7dll9	651	9	.	.	.
cord-023443-pvz7dll9	652	1	Interferon	interferon	NN
cord-023443-pvz7dll9	652	2	-	-	HYPH
cord-023443-pvz7dll9	652	3	a	a	NN
cord-023443-pvz7dll9	652	4	/	/	SYM
cord-023443-pvz7dll9	652	5	b	b	NN
cord-023443-pvz7dll9	652	6	(	(	-LRB-
cord-023443-pvz7dll9	652	7	IFN	IFN	NNP
cord-023443-pvz7dll9	652	8	-	-	HYPH
cord-023443-pvz7dll9	652	9	a	a	NNP
cord-023443-pvz7dll9	652	10	/	/	SYM
cord-023443-pvz7dll9	652	11	b	b	NN
cord-023443-pvz7dll9	652	12	)	)	-RRB-
cord-023443-pvz7dll9	652	13	is	be	VBZ
cord-023443-pvz7dll9	652	14	increasingly	increasingly	RB
cord-023443-pvz7dll9	652	15	used	use	VBN
cord-023443-pvz7dll9	652	16	as	as	IN
cord-023443-pvz7dll9	652	17	antiviral	antiviral	JJ
cord-023443-pvz7dll9	652	18	and	and	CC
cord-023443-pvz7dll9	652	19	immunomodulatory	immunomodulatory	JJ
cord-023443-pvz7dll9	652	20	therapies	therapy	NNS
cord-023443-pvz7dll9	652	21	.	.	.
cord-023443-pvz7dll9	653	1	Unfortunately	unfortunately	RB
cord-023443-pvz7dll9	653	2	,	,	,
cord-023443-pvz7dll9	653	3	bioavailability	bioavailability	NN
cord-023443-pvz7dll9	653	4	varies	vary	VBZ
cord-023443-pvz7dll9	653	5	with	with	IN
cord-023443-pvz7dll9	653	6	IFN	IFN	NNP
cord-023443-pvz7dll9	653	7	species	specie	NNS
cord-023443-pvz7dll9	653	8	and	and	CC
cord-023443-pvz7dll9	653	9	mode	mode	NN
cord-023443-pvz7dll9	653	10	of	of	IN
cord-023443-pvz7dll9	653	11	administration	administration	NN
cord-023443-pvz7dll9	653	12	,	,	,
cord-023443-pvz7dll9	653	13	and	and	CC
cord-023443-pvz7dll9	653	14	all	all	DT
cord-023443-pvz7dll9	653	15	IFN	IFN	NNP
cord-023443-pvz7dll9	653	16	species	specie	NNS
cord-023443-pvz7dll9	653	17	are	be	VBP
cord-023443-pvz7dll9	653	18	potentially	potentially	RB
cord-023443-pvz7dll9	653	19	immunogenic	immunogenic	JJ
cord-023443-pvz7dll9	653	20	.	.	.
cord-023443-pvz7dll9	654	1	Assays	assay	NNS
cord-023443-pvz7dll9	654	2	for	for	IN
cord-023443-pvz7dll9	654	3	antiviral	antiviral	JJ
cord-023443-pvz7dll9	654	4	activity	activity	NN
cord-023443-pvz7dll9	654	5	(	(	-LRB-
cord-023443-pvz7dll9	654	6	IFN	IFN	NNP
cord-023443-pvz7dll9	654	7	)	)	-RRB-
cord-023443-pvz7dll9	654	8	and	and	CC
cord-023443-pvz7dll9	654	9	antiviral	antiviral	JJ
cord-023443-pvz7dll9	654	10	neutralization	neutralization	NN
cord-023443-pvz7dll9	654	11	(	(	-LRB-
cord-023443-pvz7dll9	654	12	antibodies	antibody	NNS
cord-023443-pvz7dll9	654	13	,	,	,
cord-023443-pvz7dll9	654	14	NAb	NAb	NNS
cord-023443-pvz7dll9	654	15	)	)	-RRB-
cord-023443-pvz7dll9	654	16	have	have	VBP
cord-023443-pvz7dll9	654	17	been	be	VBN
cord-023443-pvz7dll9	654	18	used	use	VBN
cord-023443-pvz7dll9	654	19	for	for	IN
cord-023443-pvz7dll9	654	20	some	some	DT
cord-023443-pvz7dll9	654	21	time	time	NN
cord-023443-pvz7dll9	654	22	to	to	TO
cord-023443-pvz7dll9	654	23	monitor	monitor	VB
cord-023443-pvz7dll9	654	24	patients	patient	NNS
cord-023443-pvz7dll9	654	25	on	on	IN
cord-023443-pvz7dll9	654	26	IFN	IFN	NNP
cord-023443-pvz7dll9	654	27	biologicals	biological	NNS
cord-023443-pvz7dll9	654	28	.	.	.
cord-023443-pvz7dll9	655	1	These	these	DT
cord-023443-pvz7dll9	655	2	assays	assay	NNS
cord-023443-pvz7dll9	655	3	require	require	VBP
cord-023443-pvz7dll9	655	4	laborious	laborious	JJ
cord-023443-pvz7dll9	655	5	titrations	titration	NNS
cord-023443-pvz7dll9	655	6	making	make	VBG
cord-023443-pvz7dll9	655	7	them	-PRON-	PRP
cord-023443-pvz7dll9	655	8	unsuitable	unsuitable	JJ
cord-023443-pvz7dll9	655	9	for	for	IN
cord-023443-pvz7dll9	655	10	large	large	JJ
cord-023443-pvz7dll9	655	11	-	-	HYPH
cord-023443-pvz7dll9	655	12	scale	scale	NN
cord-023443-pvz7dll9	655	13	clinical	clinical	JJ
cord-023443-pvz7dll9	655	14	use	use	NN
cord-023443-pvz7dll9	655	15	.	.	.
cord-023443-pvz7dll9	656	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	656	2	laboratories	laboratory	NNS
cord-023443-pvz7dll9	656	3	have	have	VBP
cord-023443-pvz7dll9	656	4	therefore	therefore	RB
cord-023443-pvz7dll9	656	5	modified	modify	VBN
cord-023443-pvz7dll9	656	6	the	the	DT
cord-023443-pvz7dll9	656	7	antiviral	antiviral	JJ
cord-023443-pvz7dll9	656	8	assays	assay	NNS
cord-023443-pvz7dll9	656	9	for	for	IN
cord-023443-pvz7dll9	656	10	IFN	IFN	NNP
cord-023443-pvz7dll9	656	11	bioactivity	bioactivity	NNP
cord-023443-pvz7dll9	656	12	and	and	CC
cord-023443-pvz7dll9	656	13	Nab	Nab	NNP
cord-023443-pvz7dll9	656	14	,	,	,
cord-023443-pvz7dll9	656	15	so	so	IN
cord-023443-pvz7dll9	656	16	that	that	IN
cord-023443-pvz7dll9	656	17	they	-PRON-	PRP
cord-023443-pvz7dll9	656	18	are	be	VBP
cord-023443-pvz7dll9	656	19	suitable	suitable	JJ
cord-023443-pvz7dll9	656	20	for	for	IN
cord-023443-pvz7dll9	656	21	large	large	JJ
cord-023443-pvz7dll9	656	22	-	-	HYPH
cord-023443-pvz7dll9	656	23	scale	scale	NN
cord-023443-pvz7dll9	656	24	screening	screening	NN
cord-023443-pvz7dll9	656	25	in	in	IN
cord-023443-pvz7dll9	656	26	specialized	specialized	JJ
cord-023443-pvz7dll9	656	27	laboratories	laboratory	NNS
cord-023443-pvz7dll9	656	28	.	.	.
cord-023443-pvz7dll9	657	1	The	the	DT
cord-023443-pvz7dll9	657	2	read	read	NN
cord-023443-pvz7dll9	657	3	-	-	HYPH
cord-023443-pvz7dll9	657	4	out	out	NN
cord-023443-pvz7dll9	657	5	is	be	VBZ
cord-023443-pvz7dll9	657	6	survival	survival	NN
cord-023443-pvz7dll9	657	7	of	of	IN
cord-023443-pvz7dll9	657	8	a	a	DT
cord-023443-pvz7dll9	657	9	subcloned	subcloned	JJ
cord-023443-pvz7dll9	657	10	A549	a549	JJ
cord-023443-pvz7dll9	657	11	cell	cell	NN
cord-023443-pvz7dll9	657	12	line	line	NN
cord-023443-pvz7dll9	657	13	in	in	IN
cord-023443-pvz7dll9	657	14	the	the	DT
cord-023443-pvz7dll9	657	15	presence	presence	NN
cord-023443-pvz7dll9	657	16	of	of	IN
cord-023443-pvz7dll9	657	17	an	an	DT
cord-023443-pvz7dll9	657	18	otherwise	otherwise	RB
cord-023443-pvz7dll9	657	19	lethal	lethal	JJ
cord-023443-pvz7dll9	657	20	amount	amount	NN
cord-023443-pvz7dll9	657	21	of	of	IN
cord-023443-pvz7dll9	657	22	virus	virus	NN
cord-023443-pvz7dll9	657	23	.	.	.
cord-023443-pvz7dll9	658	1	Thus	thus	RB
cord-023443-pvz7dll9	658	2	,	,	,
cord-023443-pvz7dll9	658	3	survival	survival	NN
cord-023443-pvz7dll9	658	4	increases	increase	NNS
cord-023443-pvz7dll9	658	5	in	in	IN
cord-023443-pvz7dll9	658	6	the	the	DT
cord-023443-pvz7dll9	658	7	presence	presence	NN
cord-023443-pvz7dll9	658	8	of	of	IN
cord-023443-pvz7dll9	658	9	type	type	NN
cord-023443-pvz7dll9	658	10	1	1	CD
cord-023443-pvz7dll9	658	11	IFN	IFN	NNP
cord-023443-pvz7dll9	658	12	and	and	CC
cord-023443-pvz7dll9	658	13	decreases	decrease	VBZ
cord-023443-pvz7dll9	658	14	in	in	IN
cord-023443-pvz7dll9	658	15	the	the	DT
cord-023443-pvz7dll9	658	16	presence	presence	NN
cord-023443-pvz7dll9	658	17	of	of	IN
cord-023443-pvz7dll9	658	18	NAb	NAb	NNS
cord-023443-pvz7dll9	658	19	against	against	IN
cord-023443-pvz7dll9	658	20	the	the	DT
cord-023443-pvz7dll9	658	21	IFN	IFN	NNP
cord-023443-pvz7dll9	658	22	added	add	VBD
cord-023443-pvz7dll9	658	23	to	to	IN
cord-023443-pvz7dll9	658	24	the	the	DT
cord-023443-pvz7dll9	658	25	cells	cell	NNS
cord-023443-pvz7dll9	658	26	.	.	.
cord-023443-pvz7dll9	659	1	MxA	MxA	NNP
cord-023443-pvz7dll9	659	2	is	be	VBZ
cord-023443-pvz7dll9	659	3	induced	induce	VBN
cord-023443-pvz7dll9	659	4	by	by	IN
cord-023443-pvz7dll9	659	5	type	type	NN
cord-023443-pvz7dll9	659	6	1	1	CD
cord-023443-pvz7dll9	659	7	IFN	IFN	NNP
cord-023443-pvz7dll9	659	8	and	and	CC
cord-023443-pvz7dll9	659	9	can	can	MD
cord-023443-pvz7dll9	659	10	be	be	VB
cord-023443-pvz7dll9	659	11	used	use	VBN
cord-023443-pvz7dll9	659	12	for	for	IN
cord-023443-pvz7dll9	659	13	measuring	measure	VBG
cord-023443-pvz7dll9	659	14	the	the	DT
cord-023443-pvz7dll9	659	15	Nab	Nab	NNP
cord-023443-pvz7dll9	659	16	activity	activity	NN
cord-023443-pvz7dll9	659	17	.	.	.
cord-023443-pvz7dll9	660	1	In	in	IN
cord-023443-pvz7dll9	660	2	another	another	DT
cord-023443-pvz7dll9	660	3	assay	assay	NN
cord-023443-pvz7dll9	660	4	,	,	,
cord-023443-pvz7dll9	660	5	the	the	DT
cord-023443-pvz7dll9	660	6	MxA	mxa	NN
cord-023443-pvz7dll9	660	7	level	level	NN
cord-023443-pvz7dll9	660	8	in	in	IN
cord-023443-pvz7dll9	660	9	the	the	DT
cord-023443-pvz7dll9	660	10	A549	a549	JJ
cord-023443-pvz7dll9	660	11	cell	cell	NN
cord-023443-pvz7dll9	660	12	line	line	NN
cord-023443-pvz7dll9	660	13	is	be	VBZ
cord-023443-pvz7dll9	660	14	measured	measure	VBN
cord-023443-pvz7dll9	660	15	.	.	.
cord-023443-pvz7dll9	661	1	In	in	IN
cord-023443-pvz7dll9	661	2	an	an	DT
cord-023443-pvz7dll9	661	3	attempt	attempt	NN
cord-023443-pvz7dll9	661	4	to	to	TO
cord-023443-pvz7dll9	661	5	find	find	VB
cord-023443-pvz7dll9	661	6	a	a	DT
cord-023443-pvz7dll9	661	7	new	new	JJ
cord-023443-pvz7dll9	661	8	and	and	CC
cord-023443-pvz7dll9	661	9	better	well	JJR
cord-023443-pvz7dll9	661	10	reporter	reporter	NN
cord-023443-pvz7dll9	661	11	gene	gene	NN
cord-023443-pvz7dll9	661	12	for	for	IN
cord-023443-pvz7dll9	661	13	type	type	NN
cord-023443-pvz7dll9	661	14	1	1	CD
cord-023443-pvz7dll9	661	15	IFN	IFN	NNP
cord-023443-pvz7dll9	661	16	than	than	IN
cord-023443-pvz7dll9	661	17	MxA	mxa	NN
cord-023443-pvz7dll9	661	18	and	and	CC
cord-023443-pvz7dll9	661	19	genes	gene	NNS
cord-023443-pvz7dll9	661	20	specific	specific	JJ
cord-023443-pvz7dll9	661	21	for	for	IN
cord-023443-pvz7dll9	661	22	either	either	CC
cord-023443-pvz7dll9	661	23	IFN	IFN	NNP
cord-023443-pvz7dll9	661	24	-	-	HYPH
cord-023443-pvz7dll9	661	25	a	a	NN
cord-023443-pvz7dll9	661	26	or	or	CC
cord-023443-pvz7dll9	661	27	-b	-b	SYM
cord-023443-pvz7dll9	661	28	,	,	,
cord-023443-pvz7dll9	661	29	a	a	DT
cord-023443-pvz7dll9	661	30	micro	micro	JJ
cord-023443-pvz7dll9	661	31	array	array	NN
cord-023443-pvz7dll9	661	32	screen	screen	NN
cord-023443-pvz7dll9	661	33	was	be	VBD
cord-023443-pvz7dll9	661	34	carried	carry	VBN
cord-023443-pvz7dll9	661	35	using	use	VBG
cord-023443-pvz7dll9	661	36	the	the	DT
cord-023443-pvz7dll9	661	37	U133A	U133A	NNP
cord-023443-pvz7dll9	661	38	chip	chip	NN
cord-023443-pvz7dll9	661	39	from	from	IN
cord-023443-pvz7dll9	661	40	Affymetrix	Affymetrix	NNP
cord-023443-pvz7dll9	661	41	.	.	.
cord-023443-pvz7dll9	662	1	The	the	DT
cord-023443-pvz7dll9	662	2	expression	expression	NN
cord-023443-pvz7dll9	662	3	of	of	IN
cord-023443-pvz7dll9	662	4	22,000	22,000	CD
cord-023443-pvz7dll9	662	5	genes	gene	NNS
cord-023443-pvz7dll9	662	6	can	can	MD
cord-023443-pvz7dll9	662	7	be	be	VB
cord-023443-pvz7dll9	662	8	studied	study	VBN
cord-023443-pvz7dll9	662	9	simultaneous	simultaneous	JJ
cord-023443-pvz7dll9	662	10	with	with	IN
cord-023443-pvz7dll9	662	11	this	this	DT
cord-023443-pvz7dll9	662	12	technology	technology	NN
cord-023443-pvz7dll9	662	13	.	.	.
cord-023443-pvz7dll9	663	1	The	the	DT
cord-023443-pvz7dll9	663	2	results	result	NNS
cord-023443-pvz7dll9	663	3	will	will	MD
cord-023443-pvz7dll9	663	4	be	be	VB
cord-023443-pvz7dll9	663	5	presented	present	VBN
cord-023443-pvz7dll9	663	6	at	at	IN
cord-023443-pvz7dll9	663	7	the	the	DT
cord-023443-pvz7dll9	663	8	conference	conference	NN
cord-023443-pvz7dll9	663	9	.	.	.
cord-023443-pvz7dll9	664	1	In	in	IN
cord-023443-pvz7dll9	664	2	our	-PRON-	PRP$
cord-023443-pvz7dll9	664	3	laboratory	laboratory	NN
cord-023443-pvz7dll9	664	4	,	,	,
cord-023443-pvz7dll9	664	5	we	-PRON-	PRP
cord-023443-pvz7dll9	664	6	have	have	VBP
cord-023443-pvz7dll9	664	7	developed	develop	VBN
cord-023443-pvz7dll9	664	8	a	a	DT
cord-023443-pvz7dll9	664	9	database	database	NN
cord-023443-pvz7dll9	664	10	system	system	NN
cord-023443-pvz7dll9	664	11	,	,	,
cord-023443-pvz7dll9	664	12	which	which	WDT
cord-023443-pvz7dll9	664	13	we	-PRON-	PRP
cord-023443-pvz7dll9	664	14	believe	believe	VBP
cord-023443-pvz7dll9	664	15	is	be	VBZ
cord-023443-pvz7dll9	664	16	of	of	IN
cord-023443-pvz7dll9	664	17	immediate	immediate	JJ
cord-023443-pvz7dll9	664	18	interest	interest	NN
cord-023443-pvz7dll9	664	19	to	to	IN
cord-023443-pvz7dll9	664	20	the	the	DT
cord-023443-pvz7dll9	664	21	general	general	JJ
cord-023443-pvz7dll9	664	22	scientific	scientific	JJ
cord-023443-pvz7dll9	664	23	community	community	NN
cord-023443-pvz7dll9	664	24	.	.	.
cord-023443-pvz7dll9	665	1	The	the	DT
cord-023443-pvz7dll9	665	2	database	database	NN
cord-023443-pvz7dll9	665	3	represents	represent	VBZ
cord-023443-pvz7dll9	665	4	a	a	DT
cord-023443-pvz7dll9	665	5	computerbased	computerbased	JJ
cord-023443-pvz7dll9	665	6	replacement	replacement	NN
cord-023443-pvz7dll9	665	7	for	for	IN
cord-023443-pvz7dll9	665	8	the	the	DT
cord-023443-pvz7dll9	665	9	laboratory	laboratory	NN
cord-023443-pvz7dll9	665	10	notebooks	notebook	NNS
cord-023443-pvz7dll9	665	11	used	use	VBN
cord-023443-pvz7dll9	665	12	in	in	IN
cord-023443-pvz7dll9	665	13	the	the	DT
cord-023443-pvz7dll9	665	14	majority	majority	NN
cord-023443-pvz7dll9	665	15	of	of	IN
cord-023443-pvz7dll9	665	16	research	research	NN
cord-023443-pvz7dll9	665	17	laboratories	laboratory	NNS
cord-023443-pvz7dll9	665	18	worldwide	worldwide	RB
cord-023443-pvz7dll9	665	19	.	.	.
cord-023443-pvz7dll9	666	1	In	in	IN
cord-023443-pvz7dll9	666	2	addition	addition	NN
cord-023443-pvz7dll9	666	3	,	,	,
cord-023443-pvz7dll9	666	4	the	the	DT
cord-023443-pvz7dll9	666	5	database	database	NN
cord-023443-pvz7dll9	666	6	provides	provide	VBZ
cord-023443-pvz7dll9	666	7	an	an	DT
cord-023443-pvz7dll9	666	8	effective	effective	JJ
cord-023443-pvz7dll9	666	9	tool	tool	NN
cord-023443-pvz7dll9	666	10	for	for	IN
cord-023443-pvz7dll9	666	11	organizing	organize	VBG
cord-023443-pvz7dll9	666	12	and	and	CC
cord-023443-pvz7dll9	666	13	managing	manage	VBG
cord-023443-pvz7dll9	666	14	laboratory	laboratory	NN
cord-023443-pvz7dll9	666	15	information	information	NN
cord-023443-pvz7dll9	666	16	at	at	IN
cord-023443-pvz7dll9	666	17	all	all	DT
cord-023443-pvz7dll9	666	18	levels	level	NNS
cord-023443-pvz7dll9	666	19	,	,	,
cord-023443-pvz7dll9	666	20	spanning	span	VBG
cord-023443-pvz7dll9	666	21	from	from	IN
cord-023443-pvz7dll9	666	22	managing	manage	VBG
cord-023443-pvz7dll9	666	23	and	and	CC
cord-023443-pvz7dll9	666	24	revising	revise	VBG
cord-023443-pvz7dll9	666	25	standard	standard	JJ
cord-023443-pvz7dll9	666	26	operating	operate	VBG
cord-023443-pvz7dll9	666	27	procedures	procedure	NNS
cord-023443-pvz7dll9	666	28	and	and	CC
cord-023443-pvz7dll9	666	29	producing	produce	VBG
cord-023443-pvz7dll9	666	30	documentation	documentation	NN
cord-023443-pvz7dll9	666	31	of	of	IN
cord-023443-pvz7dll9	666	32	research	research	NN
cord-023443-pvz7dll9	666	33	activities	activity	NNS
cord-023443-pvz7dll9	666	34	to	to	IN
cord-023443-pvz7dll9	666	35	keeping	keep	VBG
cord-023443-pvz7dll9	666	36	track	track	NN
cord-023443-pvz7dll9	666	37	of	of	IN
cord-023443-pvz7dll9	666	38	data	datum	NNS
cord-023443-pvz7dll9	666	39	and	and	CC
cord-023443-pvz7dll9	666	40	conclusions	conclusion	NNS
cord-023443-pvz7dll9	666	41	.	.	.
cord-023443-pvz7dll9	667	1	Using	use	VBG
cord-023443-pvz7dll9	667	2	the	the	DT
cord-023443-pvz7dll9	667	3	commercially	commercially	RB
cord-023443-pvz7dll9	667	4	available	available	JJ
cord-023443-pvz7dll9	667	5	database	database	NN
cord-023443-pvz7dll9	667	6	toolkit	toolkit	NN
cord-023443-pvz7dll9	667	7	software	software	NN
cord-023443-pvz7dll9	667	8	FILEMAKER	FILEMAKER	NNP
cord-023443-pvz7dll9	667	9	PRO	PRO	NNP
cord-023443-pvz7dll9	667	10	,	,	,
cord-023443-pvz7dll9	667	11	we	-PRON-	PRP
cord-023443-pvz7dll9	667	12	have	have	VBP
cord-023443-pvz7dll9	667	13	developed	develop	VBN
cord-023443-pvz7dll9	667	14	a	a	DT
cord-023443-pvz7dll9	667	15	relational	relational	JJ
cord-023443-pvz7dll9	667	16	database	database	NN
cord-023443-pvz7dll9	667	17	solution	solution	NN
cord-023443-pvz7dll9	667	18	for	for	IN
cord-023443-pvz7dll9	667	19	management	management	NN
cord-023443-pvz7dll9	667	20	of	of	IN
cord-023443-pvz7dll9	667	21	laboratory	laboratory	NN
cord-023443-pvz7dll9	667	22	information	information	NN
cord-023443-pvz7dll9	667	23	.	.	.
cord-023443-pvz7dll9	668	1	The	the	DT
cord-023443-pvz7dll9	668	2	system	system	NN
cord-023443-pvz7dll9	668	3	consists	consist	VBZ
cord-023443-pvz7dll9	668	4	of	of	IN
cord-023443-pvz7dll9	668	5	a	a	DT
cord-023443-pvz7dll9	668	6	hierarchy	hierarchy	NN
cord-023443-pvz7dll9	668	7	of	of	IN
cord-023443-pvz7dll9	668	8	five	five	CD
cord-023443-pvz7dll9	668	9	interrelated	interrelated	JJ
cord-023443-pvz7dll9	668	10	databases	database	NNS
cord-023443-pvz7dll9	668	11	,	,	,
cord-023443-pvz7dll9	668	12	each	each	DT
cord-023443-pvz7dll9	668	13	pertaining	pertain	VBG
cord-023443-pvz7dll9	668	14	to	to	IN
cord-023443-pvz7dll9	668	15	a	a	DT
cord-023443-pvz7dll9	668	16	separate	separate	JJ
cord-023443-pvz7dll9	668	17	type	type	NN
cord-023443-pvz7dll9	668	18	of	of	IN
cord-023443-pvz7dll9	668	19	information	information	NN
cord-023443-pvz7dll9	668	20	,	,	,
cord-023443-pvz7dll9	668	21	namely	namely	RB
cord-023443-pvz7dll9	668	22	,	,	,
cord-023443-pvz7dll9	668	23	overall	overall	JJ
cord-023443-pvz7dll9	668	24	project	project	NN
cord-023443-pvz7dll9	668	25	information	information	NN
cord-023443-pvz7dll9	668	26	,	,	,
cord-023443-pvz7dll9	668	27	information	information	NN
cord-023443-pvz7dll9	668	28	relating	relate	VBG
cord-023443-pvz7dll9	668	29	to	to	IN
cord-023443-pvz7dll9	668	30	individual	individual	JJ
cord-023443-pvz7dll9	668	31	experiment	experiment	NN
cord-023443-pvz7dll9	668	32	setups	setup	NNS
cord-023443-pvz7dll9	668	33	,	,	,
cord-023443-pvz7dll9	668	34	documentation	documentation	NN
cord-023443-pvz7dll9	668	35	of	of	IN
cord-023443-pvz7dll9	668	36	daily	daily	JJ
cord-023443-pvz7dll9	668	37	research	research	NN
cord-023443-pvz7dll9	668	38	activity	activity	NN
cord-023443-pvz7dll9	668	39	,	,	,
cord-023443-pvz7dll9	668	40	generated	generate	VBD
cord-023443-pvz7dll9	668	41	data	datum	NNS
cord-023443-pvz7dll9	668	42	and	and	CC
cord-023443-pvz7dll9	668	43	descriptions	description	NNS
cord-023443-pvz7dll9	668	44	of	of	IN
cord-023443-pvz7dll9	668	45	standard	standard	JJ
cord-023443-pvz7dll9	668	46	operating	operating	NN
cord-023443-pvz7dll9	668	47	procedures	procedure	NNS
cord-023443-pvz7dll9	668	48	.	.	.
cord-023443-pvz7dll9	669	1	Like	like	IN
cord-023443-pvz7dll9	669	2	other	other	JJ
cord-023443-pvz7dll9	669	3	databases	database	NNS
cord-023443-pvz7dll9	669	4	,	,	,
cord-023443-pvz7dll9	669	5	each	each	DT
cord-023443-pvz7dll9	669	6	individual	individual	JJ
cord-023443-pvz7dll9	669	7	database	database	NN
cord-023443-pvz7dll9	669	8	consists	consist	VBZ
cord-023443-pvz7dll9	669	9	of	of	IN
cord-023443-pvz7dll9	669	10	a	a	DT
cord-023443-pvz7dll9	669	11	number	number	NN
cord-023443-pvz7dll9	669	12	of	of	IN
cord-023443-pvz7dll9	669	13	records	record	NNS
cord-023443-pvz7dll9	669	14	,	,	,
cord-023443-pvz7dll9	669	15	each	each	DT
cord-023443-pvz7dll9	669	16	comprised	comprise	VBN
cord-023443-pvz7dll9	669	17	of	of	IN
cord-023443-pvz7dll9	669	18	a	a	DT
cord-023443-pvz7dll9	669	19	set	set	NN
cord-023443-pvz7dll9	669	20	of	of	IN
cord-023443-pvz7dll9	669	21	fields	field	NNS
cord-023443-pvz7dll9	669	22	in	in	IN
cord-023443-pvz7dll9	669	23	which	which	WDT
cord-023443-pvz7dll9	669	24	information	information	NN
cord-023443-pvz7dll9	669	25	is	be	VBZ
cord-023443-pvz7dll9	669	26	entered	enter	VBN
cord-023443-pvz7dll9	669	27	.	.	.
cord-023443-pvz7dll9	670	1	In	in	IN
cord-023443-pvz7dll9	670	2	each	each	DT
cord-023443-pvz7dll9	670	3	record	record	NN
cord-023443-pvz7dll9	670	4	,	,	,
cord-023443-pvz7dll9	670	5	a	a	DT
cord-023443-pvz7dll9	670	6	certain	certain	JJ
cord-023443-pvz7dll9	670	7	field	field	NN
cord-023443-pvz7dll9	670	8	is	be	VBZ
cord-023443-pvz7dll9	670	9	reserved	reserve	VBN
cord-023443-pvz7dll9	670	10	to	to	TO
cord-023443-pvz7dll9	670	11	specify	specify	VB
cord-023443-pvz7dll9	670	12	the	the	DT
cord-023443-pvz7dll9	670	13	relation	relation	NN
cord-023443-pvz7dll9	670	14	of	of	IN
cord-023443-pvz7dll9	670	15	the	the	DT
cord-023443-pvz7dll9	670	16	record	record	NN
cord-023443-pvz7dll9	670	17	to	to	IN
cord-023443-pvz7dll9	670	18	a	a	DT
cord-023443-pvz7dll9	670	19	record	record	NN
cord-023443-pvz7dll9	670	20	in	in	IN
cord-023443-pvz7dll9	670	21	another	another	DT
cord-023443-pvz7dll9	670	22	database	database	NN
cord-023443-pvz7dll9	670	23	at	at	IN
cord-023443-pvz7dll9	670	24	a	a	DT
cord-023443-pvz7dll9	670	25	higher	high	JJR
cord-023443-pvz7dll9	670	26	level	level	NN
cord-023443-pvz7dll9	670	27	.	.	.
cord-023443-pvz7dll9	671	1	Thus	thus	RB
cord-023443-pvz7dll9	671	2	,	,	,
cord-023443-pvz7dll9	671	3	the	the	DT
cord-023443-pvz7dll9	671	4	database	database	NN
cord-023443-pvz7dll9	671	5	is	be	VBZ
cord-023443-pvz7dll9	671	6	essentially	essentially	RB
cord-023443-pvz7dll9	671	7	five	five	CD
cord-023443-pvz7dll9	671	8	databases	database	NNS
cord-023443-pvz7dll9	671	9	linked	link	VBN
cord-023443-pvz7dll9	671	10	by	by	IN
cord-023443-pvz7dll9	671	11	a	a	DT
cord-023443-pvz7dll9	671	12	hierarchy	hierarchy	NN
cord-023443-pvz7dll9	671	13	of	of	IN
cord-023443-pvz7dll9	671	14	one	one	CD
cord-023443-pvz7dll9	671	15	-	-	HYPH
cord-023443-pvz7dll9	671	16	to	to	IN
cord-023443-pvz7dll9	671	17	-	-	HYPH
cord-023443-pvz7dll9	671	18	many	many	JJ
cord-023443-pvz7dll9	671	19	relations	relation	NNS
cord-023443-pvz7dll9	671	20	,	,	,
cord-023443-pvz7dll9	671	21	organizing	organize	VBG
cord-023443-pvz7dll9	671	22	information	information	NN
cord-023443-pvz7dll9	671	23	in	in	IN
cord-023443-pvz7dll9	671	24	a	a	DT
cord-023443-pvz7dll9	671	25	folder	folder	NN
cord-023443-pvz7dll9	671	26	-	-	HYPH
cord-023443-pvz7dll9	671	27	like	like	JJ
cord-023443-pvz7dll9	671	28	structure	structure	NN
cord-023443-pvz7dll9	671	29	.	.	.
cord-023443-pvz7dll9	672	1	Importantly	importantly	RB
cord-023443-pvz7dll9	672	2	,	,	,
cord-023443-pvz7dll9	672	3	the	the	DT
cord-023443-pvz7dll9	672	4	database	database	NN
cord-023443-pvz7dll9	672	5	system	system	NN
cord-023443-pvz7dll9	672	6	allows	allow	VBZ
cord-023443-pvz7dll9	672	7	multiple	multiple	JJ
cord-023443-pvz7dll9	672	8	users	user	NNS
cord-023443-pvz7dll9	672	9	to	to	TO
cord-023443-pvz7dll9	672	10	access	access	VB
cord-023443-pvz7dll9	672	11	and	and	CC
cord-023443-pvz7dll9	672	12	edit	edit	VB
cord-023443-pvz7dll9	672	13	records	record	NNS
cord-023443-pvz7dll9	672	14	simultaneously	simultaneously	RB
cord-023443-pvz7dll9	672	15	,	,	,
cord-023443-pvz7dll9	672	16	and	and	CC
cord-023443-pvz7dll9	672	17	the	the	DT
cord-023443-pvz7dll9	672	18	data	datum	NNS
cord-023443-pvz7dll9	672	19	entered	enter	VBD
cord-023443-pvz7dll9	672	20	in	in	IN
cord-023443-pvz7dll9	672	21	one	one	CD
cord-023443-pvz7dll9	672	22	database	database	NN
cord-023443-pvz7dll9	672	23	immediately	immediately	RB
cord-023443-pvz7dll9	672	24	becomes	become	VBZ
cord-023443-pvz7dll9	672	25	accessible	accessible	JJ
cord-023443-pvz7dll9	672	26	through	through	IN
cord-023443-pvz7dll9	672	27	the	the	DT
cord-023443-pvz7dll9	672	28	other	other	JJ
cord-023443-pvz7dll9	672	29	databases	database	NNS
cord-023443-pvz7dll9	672	30	.	.	.
cord-023443-pvz7dll9	673	1	The	the	DT
cord-023443-pvz7dll9	673	2	limitations	limitation	NNS
cord-023443-pvz7dll9	673	3	of	of	IN
cord-023443-pvz7dll9	673	4	laboratory	laboratory	NN
cord-023443-pvz7dll9	673	5	notebooks	notebook	NNS
cord-023443-pvz7dll9	673	6	are	be	VBP
cord-023443-pvz7dll9	673	7	apparent	apparent	JJ
cord-023443-pvz7dll9	673	8	when	when	WRB
cord-023443-pvz7dll9	673	9	looking	look	VBG
cord-023443-pvz7dll9	673	10	for	for	IN
cord-023443-pvz7dll9	673	11	information	information	NN
cord-023443-pvz7dll9	673	12	,	,	,
cord-023443-pvz7dll9	673	13	which	which	WDT
cord-023443-pvz7dll9	673	14	is	be	VBZ
cord-023443-pvz7dll9	673	15	dispersed	disperse	VBN
cord-023443-pvz7dll9	673	16	throughout	throughout	IN
cord-023443-pvz7dll9	673	17	one	one	CD
cord-023443-pvz7dll9	673	18	or	or	CC
cord-023443-pvz7dll9	673	19	more	more	JJR
cord-023443-pvz7dll9	673	20	notebooks	notebook	NNS
cord-023443-pvz7dll9	673	21	,	,	,
cord-023443-pvz7dll9	673	22	or	or	CC
cord-023443-pvz7dll9	673	23	possibly	possibly	RB
cord-023443-pvz7dll9	673	24	on	on	IN
cord-023443-pvz7dll9	673	25	loose	loose	JJ
cord-023443-pvz7dll9	673	26	sheets	sheet	NNS
cord-023443-pvz7dll9	673	27	of	of	IN
cord-023443-pvz7dll9	673	28	paper	paper	NN
cord-023443-pvz7dll9	673	29	or	or	CC
cord-023443-pvz7dll9	673	30	printouts	printout	NNS
cord-023443-pvz7dll9	673	31	'	'	POS
cord-023443-pvz7dll9	673	32	somewhere	somewhere	RB
cord-023443-pvz7dll9	673	33	'	'	''
cord-023443-pvz7dll9	673	34	.	.	.
cord-023443-pvz7dll9	674	1	The	the	DT
cord-023443-pvz7dll9	674	2	often	often	RB
cord-023443-pvz7dll9	674	3	complicated	complicated	JJ
cord-023443-pvz7dll9	674	4	process	process	NN
cord-023443-pvz7dll9	674	5	of	of	IN
cord-023443-pvz7dll9	674	6	gathering	gather	VBG
cord-023443-pvz7dll9	674	7	laboratory	laboratory	NN
cord-023443-pvz7dll9	674	8	data	datum	NNS
cord-023443-pvz7dll9	674	9	or	or	CC
cord-023443-pvz7dll9	674	10	results	result	NNS
cord-023443-pvz7dll9	674	11	when	when	WRB
cord-023443-pvz7dll9	674	12	writing	write	VBG
cord-023443-pvz7dll9	674	13	grant	grant	NN
cord-023443-pvz7dll9	674	14	applications	application	NNS
cord-023443-pvz7dll9	674	15	or	or	CC
cord-023443-pvz7dll9	674	16	research	research	NN
cord-023443-pvz7dll9	674	17	papers	paper	NNS
cord-023443-pvz7dll9	674	18	is	be	VBZ
cord-023443-pvz7dll9	674	19	made	make	VBN
cord-023443-pvz7dll9	674	20	considerably	considerably	RB
cord-023443-pvz7dll9	674	21	easier	easy	JJR
cord-023443-pvz7dll9	674	22	with	with	IN
cord-023443-pvz7dll9	674	23	the	the	DT
cord-023443-pvz7dll9	674	24	database	database	NN
cord-023443-pvz7dll9	674	25	system	system	NN
cord-023443-pvz7dll9	674	26	.	.	.
cord-023443-pvz7dll9	675	1	Thus	thus	RB
cord-023443-pvz7dll9	675	2	,	,	,
cord-023443-pvz7dll9	675	3	the	the	DT
cord-023443-pvz7dll9	675	4	database	database	NN
cord-023443-pvz7dll9	675	5	solution	solution	NN
cord-023443-pvz7dll9	675	6	presented	present	VBN
cord-023443-pvz7dll9	675	7	should	should	MD
cord-023443-pvz7dll9	675	8	be	be	VB
cord-023443-pvz7dll9	675	9	broadly	broadly	RB
cord-023443-pvz7dll9	675	10	attractive	attractive	JJ
cord-023443-pvz7dll9	675	11	to	to	IN
cord-023443-pvz7dll9	675	12	researchers	researcher	NNS
cord-023443-pvz7dll9	675	13	,	,	,
cord-023443-pvz7dll9	675	14	irrespective	irrespective	RB
cord-023443-pvz7dll9	675	15	of	of	IN
cord-023443-pvz7dll9	675	16	their	-PRON-	PRP$
cord-023443-pvz7dll9	675	17	scientific	scientific	JJ
cord-023443-pvz7dll9	675	18	discipline	discipline	NN
cord-023443-pvz7dll9	675	19	.	.	.
cord-023443-pvz7dll9	676	1	An	an	DT
cord-023443-pvz7dll9	676	2	effective	effective	JJ
cord-023443-pvz7dll9	676	3	SARS	SARS	NNP
cord-023443-pvz7dll9	676	4	vaccine	vaccine	NN
cord-023443-pvz7dll9	676	5	is	be	VBZ
cord-023443-pvz7dll9	676	6	likely	likely	JJ
cord-023443-pvz7dll9	676	7	to	to	TO
cord-023443-pvz7dll9	676	8	include	include	VB
cord-023443-pvz7dll9	676	9	components	component	NNS
cord-023443-pvz7dll9	676	10	that	that	WDT
cord-023443-pvz7dll9	676	11	can	can	MD
cord-023443-pvz7dll9	676	12	induce	induce	VB
cord-023443-pvz7dll9	676	13	specific	specific	JJ
cord-023443-pvz7dll9	676	14	cytotoxic	cytotoxic	JJ
cord-023443-pvz7dll9	676	15	T	t	NN
cord-023443-pvz7dll9	676	16	-	-	HYPH
cord-023443-pvz7dll9	676	17	cell	cell	NN
cord-023443-pvz7dll9	676	18	(	(	-LRB-
cord-023443-pvz7dll9	676	19	CTL	CTL	NNP
cord-023443-pvz7dll9	676	20	)	)	-RRB-
cord-023443-pvz7dll9	676	21	responses	response	NNS
cord-023443-pvz7dll9	676	22	.	.	.
cord-023443-pvz7dll9	677	1	The	the	DT
cord-023443-pvz7dll9	677	2	specificities	specificity	NNS
cord-023443-pvz7dll9	677	3	of	of	IN
cord-023443-pvz7dll9	677	4	such	such	JJ
cord-023443-pvz7dll9	677	5	responses	response	NNS
cord-023443-pvz7dll9	677	6	are	be	VBP
cord-023443-pvz7dll9	677	7	governed	govern	VBN
cord-023443-pvz7dll9	677	8	by	by	IN
cord-023443-pvz7dll9	677	9	HLArestricted	hlarestricted	JJ
cord-023443-pvz7dll9	677	10	presentation	presentation	NN
cord-023443-pvz7dll9	677	11	of	of	IN
cord-023443-pvz7dll9	677	12	SARS	SARS	NNP
cord-023443-pvz7dll9	677	13	-	-	HYPH
cord-023443-pvz7dll9	677	14	derived	derive	VBN
cord-023443-pvz7dll9	677	15	peptide	peptide	NN
cord-023443-pvz7dll9	677	16	epitopes	epitope	NNS
cord-023443-pvz7dll9	677	17	.	.	.
cord-023443-pvz7dll9	678	1	Exact	exact	JJ
cord-023443-pvz7dll9	678	2	knowledge	knowledge	NN
cord-023443-pvz7dll9	678	3	of	of	IN
cord-023443-pvz7dll9	678	4	how	how	WRB
cord-023443-pvz7dll9	678	5	the	the	DT
cord-023443-pvz7dll9	678	6	immune	immune	JJ
cord-023443-pvz7dll9	678	7	system	system	NN
cord-023443-pvz7dll9	678	8	handles	handle	VBZ
cord-023443-pvz7dll9	678	9	protein	protein	NN
cord-023443-pvz7dll9	678	10	antigens	antigen	NNS
cord-023443-pvz7dll9	678	11	would	would	MD
cord-023443-pvz7dll9	678	12	allow	allow	VB
cord-023443-pvz7dll9	678	13	for	for	IN
cord-023443-pvz7dll9	678	14	the	the	DT
cord-023443-pvz7dll9	678	15	identification	identification	NN
cord-023443-pvz7dll9	678	16	of	of	IN
cord-023443-pvz7dll9	678	17	such	such	JJ
cord-023443-pvz7dll9	678	18	linear	linear	JJ
cord-023443-pvz7dll9	678	19	sequences	sequence	NNS
cord-023443-pvz7dll9	678	20	directly	directly	RB
cord-023443-pvz7dll9	678	21	from	from	IN
cord-023443-pvz7dll9	678	22	genomic	genomic	JJ
cord-023443-pvz7dll9	678	23	/	/	SYM
cord-023443-pvz7dll9	678	24	proteomic	proteomic	JJ
cord-023443-pvz7dll9	678	25	sequence	sequence	NN
cord-023443-pvz7dll9	678	26	information	information	NN
cord-023443-pvz7dll9	678	27	.	.	.
cord-023443-pvz7dll9	679	1	The	the	DT
cord-023443-pvz7dll9	679	2	latter	latter	JJ
cord-023443-pvz7dll9	679	3	was	be	VBD
cord-023443-pvz7dll9	679	4	recently	recently	RB
cord-023443-pvz7dll9	679	5	established	establish	VBN
cord-023443-pvz7dll9	679	6	when	when	WRB
cord-023443-pvz7dll9	679	7	a	a	DT
cord-023443-pvz7dll9	679	8	causative	causative	JJ
cord-023443-pvz7dll9	679	9	coronavirus	coronavirus	NN
cord-023443-pvz7dll9	679	10	(	(	-LRB-
cord-023443-pvz7dll9	679	11	SARS	SARS	NNP
cord-023443-pvz7dll9	679	12	CoV	CoV	NNP
cord-023443-pvz7dll9	679	13	)	)	-RRB-
cord-023443-pvz7dll9	679	14	was	be	VBD
cord-023443-pvz7dll9	679	15	isolated	isolate	VBN
cord-023443-pvz7dll9	679	16	and	and	CC
cord-023443-pvz7dll9	679	17	full	full	JJ
cord-023443-pvz7dll9	679	18	-	-	HYPH
cord-023443-pvz7dll9	679	19	length	length	NN
cord-023443-pvz7dll9	679	20	sequenced	sequence	VBN
cord-023443-pvz7dll9	679	21	.	.	.
cord-023443-pvz7dll9	680	1	Here	here	RB
cord-023443-pvz7dll9	680	2	,	,	,
cord-023443-pvz7dll9	680	3	we	-PRON-	PRP
cord-023443-pvz7dll9	680	4	have	have	VBP
cord-023443-pvz7dll9	680	5	combined	combine	VBN
cord-023443-pvz7dll9	680	6	advanced	advanced	JJ
cord-023443-pvz7dll9	680	7	bioinformatics	bioinformatic	NNS
cord-023443-pvz7dll9	680	8	and	and	CC
cord-023443-pvz7dll9	680	9	high	high	JJ
cord-023443-pvz7dll9	680	10	-	-	HYPH
cord-023443-pvz7dll9	680	11	throughput	throughput	NN
cord-023443-pvz7dll9	680	12	immunology	immunology	NN
cord-023443-pvz7dll9	680	13	to	to	TO
cord-023443-pvz7dll9	680	14	perform	perform	VB
cord-023443-pvz7dll9	680	15	an	an	DT
cord-023443-pvz7dll9	680	16	HLA	HLA	NNP
cord-023443-pvz7dll9	680	17	supertype	supertype	NN
cord-023443-pvz7dll9	680	18	,	,	,
cord-023443-pvz7dll9	680	19	genome	genome	NN
cord-023443-pvz7dll9	680	20	-	-	HYPH
cord-023443-pvz7dll9	680	21	wide	wide	JJ
cord-023443-pvz7dll9	680	22	scan	scan	NN
cord-023443-pvz7dll9	680	23	for	for	IN
cord-023443-pvz7dll9	680	24	SARS	SARS	NNP
cord-023443-pvz7dll9	680	25	-	-	HYPH
cord-023443-pvz7dll9	680	26	specific	specific	JJ
cord-023443-pvz7dll9	680	27	cytotoxic	cytotoxic	JJ
cord-023443-pvz7dll9	680	28	T	t	NN
cord-023443-pvz7dll9	680	29	cell	cell	NN
cord-023443-pvz7dll9	680	30	epitopes	epitope	NNS
cord-023443-pvz7dll9	680	31	.	.	.
cord-023443-pvz7dll9	681	1	The	the	DT
cord-023443-pvz7dll9	681	2	scan	scan	NN
cord-023443-pvz7dll9	681	3	includes	include	VBZ
cord-023443-pvz7dll9	681	4	all	all	DT
cord-023443-pvz7dll9	681	5	nine	nine	CD
cord-023443-pvz7dll9	681	6	human	human	JJ
cord-023443-pvz7dll9	681	7	HLA	HLA	NNP
cord-023443-pvz7dll9	681	8	supertypes	supertype	NNS
cord-023443-pvz7dll9	681	9	in	in	IN
cord-023443-pvz7dll9	681	10	total	total	JJ
cord-023443-pvz7dll9	681	11	covering	covering	NN
cord-023443-pvz7dll9	681	12	>	>	SYM
cord-023443-pvz7dll9	681	13	99	99	CD
cord-023443-pvz7dll9	681	14	%	%	NN
cord-023443-pvz7dll9	681	15	of	of	IN
cord-023443-pvz7dll9	681	16	all	all	DT
cord-023443-pvz7dll9	681	17	major	major	JJ
cord-023443-pvz7dll9	681	18	human	human	JJ
cord-023443-pvz7dll9	681	19	populations	population	NNS
cord-023443-pvz7dll9	681	20	.	.	.
cord-023443-pvz7dll9	682	1	For	for	IN
cord-023443-pvz7dll9	682	2	each	each	DT
cord-023443-pvz7dll9	682	3	HLA	HLA	NNP
cord-023443-pvz7dll9	682	4	supertype	supertype	NN
cord-023443-pvz7dll9	682	5	,	,	,
cord-023443-pvz7dll9	682	6	we	-PRON-	PRP
cord-023443-pvz7dll9	682	7	have	have	VBP
cord-023443-pvz7dll9	682	8	selected	select	VBN
cord-023443-pvz7dll9	682	9	the	the	DT
cord-023443-pvz7dll9	682	10	15	15	CD
cord-023443-pvz7dll9	682	11	top	top	JJ
cord-023443-pvz7dll9	682	12	candidates	candidate	NNS
cord-023443-pvz7dll9	682	13	for	for	IN
cord-023443-pvz7dll9	682	14	test	test	NN
cord-023443-pvz7dll9	682	15	in	in	IN
cord-023443-pvz7dll9	682	16	biochemical	biochemical	JJ
cord-023443-pvz7dll9	682	17	-	-	HYPH
cord-023443-pvz7dll9	682	18	binding	bind	VBG
cord-023443-pvz7dll9	682	19	assays	assay	NNS
cord-023443-pvz7dll9	682	20	.	.	.
cord-023443-pvz7dll9	683	1	At	at	IN
cord-023443-pvz7dll9	683	2	this	this	DT
cord-023443-pvz7dll9	683	3	time	time	NN
cord-023443-pvz7dll9	683	4	(	(	-LRB-
cord-023443-pvz7dll9	683	5	approximately	approximately	RB
cord-023443-pvz7dll9	683	6	6	6	CD
cord-023443-pvz7dll9	683	7	months	month	NNS
cord-023443-pvz7dll9	683	8	after	after	IN
cord-023443-pvz7dll9	683	9	the	the	DT
cord-023443-pvz7dll9	683	10	genome	genome	NN
cord-023443-pvz7dll9	683	11	was	be	VBD
cord-023443-pvz7dll9	683	12	established	establish	VBN
cord-023443-pvz7dll9	683	13	)	)	-RRB-
cord-023443-pvz7dll9	683	14	,	,	,
cord-023443-pvz7dll9	683	15	we	-PRON-	PRP
cord-023443-pvz7dll9	683	16	have	have	VBP
cord-023443-pvz7dll9	683	17	tested	test	VBN
cord-023443-pvz7dll9	683	18	the	the	DT
cord-023443-pvz7dll9	683	19	majority	majority	NN
cord-023443-pvz7dll9	683	20	of	of	IN
cord-023443-pvz7dll9	683	21	the	the	DT
cord-023443-pvz7dll9	683	22	HLA	HLA	NNP
cord-023443-pvz7dll9	683	23	supertypes	supertype	NNS
cord-023443-pvz7dll9	683	24	and	and	CC
cord-023443-pvz7dll9	683	25	identified	identify	VBD
cord-023443-pvz7dll9	683	26	almost	almost	RB
cord-023443-pvz7dll9	683	27	100	100	CD
cord-023443-pvz7dll9	683	28	potential	potential	JJ
cord-023443-pvz7dll9	683	29	vaccine	vaccine	NN
cord-023443-pvz7dll9	683	30	candidates	candidate	NNS
cord-023443-pvz7dll9	683	31	.	.	.
cord-023443-pvz7dll9	684	1	These	these	DT
cord-023443-pvz7dll9	684	2	should	should	MD
cord-023443-pvz7dll9	684	3	be	be	VB
cord-023443-pvz7dll9	684	4	further	further	RB
cord-023443-pvz7dll9	684	5	validated	validate	VBN
cord-023443-pvz7dll9	684	6	in	in	IN
cord-023443-pvz7dll9	684	7	SARS	SARS	NNP
cord-023443-pvz7dll9	684	8	survivors	survivor	NNS
cord-023443-pvz7dll9	684	9	and	and	CC
cord-023443-pvz7dll9	684	10	used	use	VBD
cord-023443-pvz7dll9	684	11	for	for	IN
cord-023443-pvz7dll9	684	12	vaccine	vaccine	NN
cord-023443-pvz7dll9	684	13	formulation	formulation	NN
cord-023443-pvz7dll9	684	14	.	.	.
cord-023443-pvz7dll9	685	1	We	-PRON-	PRP
cord-023443-pvz7dll9	685	2	suggest	suggest	VBP
cord-023443-pvz7dll9	685	3	that	that	IN
cord-023443-pvz7dll9	685	4	immunobioinformatics	immunobioinformatic	NNS
cord-023443-pvz7dll9	685	5	may	may	MD
cord-023443-pvz7dll9	685	6	become	become	VB
cord-023443-pvz7dll9	685	7	a	a	DT
cord-023443-pvz7dll9	685	8	fast	fast	JJ
cord-023443-pvz7dll9	685	9	and	and	CC
cord-023443-pvz7dll9	685	10	valuable	valuable	JJ
cord-023443-pvz7dll9	685	11	tool	tool	NN
cord-023443-pvz7dll9	685	12	in	in	IN
cord-023443-pvz7dll9	685	13	rational	rational	JJ
cord-023443-pvz7dll9	685	14	vaccine	vaccine	NN
cord-023443-pvz7dll9	685	15	design	design	NN
cord-023443-pvz7dll9	685	16	.	.	.
cord-023443-pvz7dll9	686	1	Rationale	rationale	NN
cord-023443-pvz7dll9	686	2	:	:	:
cord-023443-pvz7dll9	687	1	Major	major	JJ
cord-023443-pvz7dll9	687	2	histocompatibility	histocompatibility	NN
cord-023443-pvz7dll9	687	3	complex	complex	NN
cord-023443-pvz7dll9	687	4	class	class	NN
cord-023443-pvz7dll9	688	1	I	-PRON-	PRP
cord-023443-pvz7dll9	688	2	(	(	-LRB-
cord-023443-pvz7dll9	688	3	MHC	MHC	NNP
cord-023443-pvz7dll9	688	4	I	I	NNP
cord-023443-pvz7dll9	688	5	)	)	-RRB-
cord-023443-pvz7dll9	688	6	molecules	molecule	NNS
cord-023443-pvz7dll9	688	7	monitor	monitor	VBP
cord-023443-pvz7dll9	688	8	the	the	DT
cord-023443-pvz7dll9	688	9	protein	protein	NN
cord-023443-pvz7dll9	688	10	content	content	NN
cord-023443-pvz7dll9	688	11	of	of	IN
cord-023443-pvz7dll9	688	12	the	the	DT
cord-023443-pvz7dll9	688	13	cell	cell	NN
cord-023443-pvz7dll9	688	14	by	by	IN
cord-023443-pvz7dll9	688	15	binding	bind	VBG
cord-023443-pvz7dll9	688	16	small	small	JJ
cord-023443-pvz7dll9	688	17	derived	derive	VBN
cord-023443-pvz7dll9	688	18	peptides	peptide	NNS
cord-023443-pvz7dll9	688	19	and	and	CC
cord-023443-pvz7dll9	688	20	presenting	present	VBG
cord-023443-pvz7dll9	688	21	them	-PRON-	PRP
cord-023443-pvz7dll9	688	22	to	to	IN
cord-023443-pvz7dll9	688	23	cytotoxic	cytotoxic	JJ
cord-023443-pvz7dll9	688	24	CD8	CD8	NNP
cord-023443-pvz7dll9	688	25	þ	þ	NNP
cord-023443-pvz7dll9	688	26	T	T	NNP
cord-023443-pvz7dll9	688	27	cells	cell	NNS
cord-023443-pvz7dll9	688	28	.	.	.
cord-023443-pvz7dll9	689	1	The	the	DT
cord-023443-pvz7dll9	689	2	goal	goal	NN
cord-023443-pvz7dll9	689	3	of	of	IN
cord-023443-pvz7dll9	689	4	the	the	DT
cord-023443-pvz7dll9	689	5	human	human	JJ
cord-023443-pvz7dll9	689	6	MHC	MHC	NNP
cord-023443-pvz7dll9	689	7	project	project	NN
cord-023443-pvz7dll9	689	8	is	be	VBZ
cord-023443-pvz7dll9	689	9	to	to	TO
cord-023443-pvz7dll9	689	10	predict	predict	VB
cord-023443-pvz7dll9	689	11	the	the	DT
cord-023443-pvz7dll9	689	12	binding	binding	NN
cord-023443-pvz7dll9	689	13	strength	strength	NN
cord-023443-pvz7dll9	689	14	of	of	IN
cord-023443-pvz7dll9	689	15	any	any	DT
cord-023443-pvz7dll9	689	16	given	give	VBN
cord-023443-pvz7dll9	689	17	peptide	peptide	NN
cord-023443-pvz7dll9	689	18	/	/	SYM
cord-023443-pvz7dll9	689	19	MHC	MHC	NNP
cord-023443-pvz7dll9	689	20	complex	complex	NN
cord-023443-pvz7dll9	689	21	.	.	.
cord-023443-pvz7dll9	690	1	This	this	DT
cord-023443-pvz7dll9	690	2	prediction	prediction	NN
cord-023443-pvz7dll9	690	3	allows	allow	VBZ
cord-023443-pvz7dll9	690	4	the	the	DT
cord-023443-pvz7dll9	690	5	design	design	NN
cord-023443-pvz7dll9	690	6	of	of	IN
cord-023443-pvz7dll9	690	7	peptide	peptide	NN
cord-023443-pvz7dll9	690	8	-	-	HYPH
cord-023443-pvz7dll9	690	9	based	base	VBN
cord-023443-pvz7dll9	690	10	vaccines	vaccine	NNS
cord-023443-pvz7dll9	690	11	.	.	.
cord-023443-pvz7dll9	691	1	The	the	DT
cord-023443-pvz7dll9	691	2	prediction	prediction	NN
cord-023443-pvz7dll9	691	3	requires	require	VBZ
cord-023443-pvz7dll9	691	4	representative	representative	JJ
cord-023443-pvz7dll9	691	5	binding	bind	VBG
cord-023443-pvz7dll9	691	6	data	datum	NNS
cord-023443-pvz7dll9	691	7	from	from	IN
cord-023443-pvz7dll9	691	8	MHC	MHC	NNP
cord-023443-pvz7dll9	691	9	alleles	allele	NNS
cord-023443-pvz7dll9	691	10	from	from	IN
cord-023443-pvz7dll9	691	11	all	all	PDT
cord-023443-pvz7dll9	691	12	the	the	DT
cord-023443-pvz7dll9	691	13	nine	nine	CD
cord-023443-pvz7dll9	691	14	HLA	HLA	NNP
cord-023443-pvz7dll9	691	15	supertypes	supertype	NNS
cord-023443-pvz7dll9	691	16	.	.	.
cord-023443-pvz7dll9	692	1	Here	here	RB
cord-023443-pvz7dll9	692	2	,	,	,
cord-023443-pvz7dll9	692	3	we	-PRON-	PRP
cord-023443-pvz7dll9	692	4	describe	describe	VBP
cord-023443-pvz7dll9	692	5	the	the	DT
cord-023443-pvz7dll9	692	6	genetic	genetic	JJ
cord-023443-pvz7dll9	692	7	construction	construction	NN
cord-023443-pvz7dll9	692	8	,	,	,
cord-023443-pvz7dll9	692	9	protein	protein	NN
cord-023443-pvz7dll9	692	10	production	production	NN
cord-023443-pvz7dll9	692	11	and	and	CC
cord-023443-pvz7dll9	692	12	purification	purification	NN
cord-023443-pvz7dll9	692	13	as	as	RB
cord-023443-pvz7dll9	692	14	well	well	RB
cord-023443-pvz7dll9	692	15	as	as	IN
cord-023443-pvz7dll9	692	16	the	the	DT
cord-023443-pvz7dll9	692	17	establishment	establishment	NN
cord-023443-pvz7dll9	692	18	-	-	HYPH
cord-023443-pvz7dll9	692	19	binding	bind	VBG
cord-023443-pvz7dll9	692	20	assays	assay	NNS
cord-023443-pvz7dll9	692	21	for	for	IN
cord-023443-pvz7dll9	692	22	two	two	CD
cord-023443-pvz7dll9	692	23	recombinant	recombinant	JJ
cord-023443-pvz7dll9	692	24	MHC	MHC	NNP
cord-023443-pvz7dll9	692	25	supertype	supertype	NN
cord-023443-pvz7dll9	692	26	alleles	allele	NNS
cord-023443-pvz7dll9	692	27	,	,	,
cord-023443-pvz7dll9	692	28	HLA	HLA	NNP
cord-023443-pvz7dll9	692	29	-	-	HYPH
cord-023443-pvz7dll9	692	30	B*1501	B*1501	NNP
cord-023443-pvz7dll9	692	31	and	and	CC
cord-023443-pvz7dll9	692	32	HLA	HLA	NNP
cord-023443-pvz7dll9	692	33	-	-	HYPH
cord-023443-pvz7dll9	692	34	B*5801	B*5801	NNP
cord-023443-pvz7dll9	692	35	.	.	.
cord-023443-pvz7dll9	693	1	Methods	method	NNS
cord-023443-pvz7dll9	693	2	:	:	:
cord-023443-pvz7dll9	693	3	Using	use	VBG
cord-023443-pvz7dll9	693	4	the	the	DT
cord-023443-pvz7dll9	693	5	Quikchange	Quikchange	NNP
cord-023443-pvz7dll9	693	6	Multisite	Multisite	NNP
cord-023443-pvz7dll9	693	7	Directed	Directed	NNP
cord-023443-pvz7dll9	693	8	Mutagenesis	Mutagenesis	NNP
cord-023443-pvz7dll9	693	9	Kit	kit	NN
cord-023443-pvz7dll9	693	10	(	(	-LRB-
cord-023443-pvz7dll9	693	11	Stratagene	Stratagene	NNP
cord-023443-pvz7dll9	693	12	)	)	-RRB-
cord-023443-pvz7dll9	693	13	,	,	,
cord-023443-pvz7dll9	693	14	codon	codon	NN
cord-023443-pvz7dll9	693	15	-	-	HYPH
cord-023443-pvz7dll9	693	16	optimized	optimize	VBN
cord-023443-pvz7dll9	693	17	genes	gene	NNS
cord-023443-pvz7dll9	693	18	encoding	encode	VBG
cord-023443-pvz7dll9	693	19	HLA	HLA	NNP
cord-023443-pvz7dll9	693	20	-	-	HYPH
cord-023443-pvz7dll9	693	21	B*1501	B*1501	NNP
cord-023443-pvz7dll9	693	22	and	and	CC
cord-023443-pvz7dll9	693	23	HLA	HLA	NNP
cord-023443-pvz7dll9	693	24	-	-	HYPH
cord-023443-pvz7dll9	693	25	B*5801	B*5801	NNP
cord-023443-pvz7dll9	693	26	are	be	VBP
cord-023443-pvz7dll9	693	27	created	create	VBN
cord-023443-pvz7dll9	693	28	.	.	.
cord-023443-pvz7dll9	694	1	The	the	DT
cord-023443-pvz7dll9	694	2	two	two	CD
cord-023443-pvz7dll9	694	3	MHC	MHC	NNP
cord-023443-pvz7dll9	694	4	I	-PRON-	PRP
cord-023443-pvz7dll9	694	5	molecules	molecule	NNS
cord-023443-pvz7dll9	694	6	are	be	VBP
cord-023443-pvz7dll9	694	7	fermented	ferment	VBN
cord-023443-pvz7dll9	694	8	and	and	CC
cord-023443-pvz7dll9	694	9	purified	purify	VBN
cord-023443-pvz7dll9	694	10	by	by	IN
cord-023443-pvz7dll9	694	11	ion	ion	NN
cord-023443-pvz7dll9	694	12	exchange	exchange	NN
cord-023443-pvz7dll9	694	13	chromatography	chromatography	NN
cord-023443-pvz7dll9	694	14	,	,	,
cord-023443-pvz7dll9	694	15	hydrophobic	hydrophobic	JJ
cord-023443-pvz7dll9	694	16	interaction	interaction	NN
cord-023443-pvz7dll9	694	17	chromatography	chromatography	NN
cord-023443-pvz7dll9	694	18	and	and	CC
cord-023443-pvz7dll9	694	19	size	size	NN
cord-023443-pvz7dll9	694	20	exclusion	exclusion	NN
cord-023443-pvz7dll9	694	21	chromatography	chromatography	NN
cord-023443-pvz7dll9	694	22	.	.	.
cord-023443-pvz7dll9	695	1	The	the	DT
cord-023443-pvz7dll9	695	2	binding	binding	NN
cord-023443-pvz7dll9	695	3	(	(	-LRB-
cord-023443-pvz7dll9	695	4	KD	KD	NNP
cord-023443-pvz7dll9	695	5	)	)	-RRB-
cord-023443-pvz7dll9	695	6	of	of	IN
cord-023443-pvz7dll9	695	7	natural	natural	JJ
cord-023443-pvz7dll9	695	8	T	T	NNP
cord-023443-pvz7dll9	695	9	-	-	HYPH
cord-023443-pvz7dll9	695	10	cell	cell	NN
cord-023443-pvz7dll9	695	11	epitopes	epitope	NNS
cord-023443-pvz7dll9	695	12	,	,	,
cord-023443-pvz7dll9	695	13	as	as	RB
cord-023443-pvz7dll9	695	14	well	well	RB
cord-023443-pvz7dll9	695	15	as	as	IN
cord-023443-pvz7dll9	695	16	predicted	predict	VBN
cord-023443-pvz7dll9	695	17	peptide	peptide	NN
cord-023443-pvz7dll9	695	18	ligands	ligand	NNS
cord-023443-pvz7dll9	695	19	,	,	,
cord-023443-pvz7dll9	695	20	is	be	VBZ
cord-023443-pvz7dll9	695	21	described	describe	VBN
cord-023443-pvz7dll9	695	22	by	by	IN
cord-023443-pvz7dll9	695	23	radioactive	radioactive	JJ
cord-023443-pvz7dll9	695	24	immunoassays	immunoassay	NNS
cord-023443-pvz7dll9	695	25	(	(	-LRB-
cord-023443-pvz7dll9	695	26	RIAs	RIAs	NNP
cord-023443-pvz7dll9	695	27	)	)	-RRB-
cord-023443-pvz7dll9	695	28	and	and	CC
cord-023443-pvz7dll9	695	29	enzyme	enzyme	NN
cord-023443-pvz7dll9	695	30	-	-	HYPH
cord-023443-pvz7dll9	695	31	linked	link	VBN
cord-023443-pvz7dll9	695	32	immunosorbent	immunosorbent	JJ
cord-023443-pvz7dll9	695	33	assays	assay	NNS
cord-023443-pvz7dll9	695	34	(	(	-LRB-
cord-023443-pvz7dll9	695	35	ELISAs	elisa	NNS
cord-023443-pvz7dll9	695	36	)	)	-RRB-
cord-023443-pvz7dll9	695	37	.	.	.
cord-023443-pvz7dll9	696	1	The	the	DT
cord-023443-pvz7dll9	696	2	MHC	MHC	NNP
cord-023443-pvz7dll9	696	3	molecules	molecule	NNS
cord-023443-pvz7dll9	696	4	are	be	VBP
cord-023443-pvz7dll9	696	5	biotinylated	biotinylate	VBN
cord-023443-pvz7dll9	696	6	during	during	IN
cord-023443-pvz7dll9	696	7	expression	expression	NN
cord-023443-pvz7dll9	696	8	.	.	.
cord-023443-pvz7dll9	697	1	Results	result	NNS
cord-023443-pvz7dll9	697	2	:	:	:
cord-023443-pvz7dll9	698	1	The	the	DT
cord-023443-pvz7dll9	698	2	expression	expression	NN
cord-023443-pvz7dll9	698	3	of	of	IN
cord-023443-pvz7dll9	698	4	MHC	MHC	NNP
cord-023443-pvz7dll9	698	5	I	-PRON-	PRP
cord-023443-pvz7dll9	698	6	resulted	result	VBD
cord-023443-pvz7dll9	698	7	in	in	IN
cord-023443-pvz7dll9	698	8	multiple	multiple	JJ
cord-023443-pvz7dll9	698	9	disulfide	disulfide	JJ
cord-023443-pvz7dll9	698	10	bond	bond	NN
cord-023443-pvz7dll9	698	11	isomers	isomer	NNS
cord-023443-pvz7dll9	698	12	,	,	,
cord-023443-pvz7dll9	698	13	which	which	WDT
cord-023443-pvz7dll9	698	14	are	be	VBP
cord-023443-pvz7dll9	698	15	separated	separate	VBN
cord-023443-pvz7dll9	698	16	by	by	IN
cord-023443-pvz7dll9	698	17	hydrophobic	hydrophobic	JJ
cord-023443-pvz7dll9	698	18	interaction	interaction	NN
cord-023443-pvz7dll9	698	19	chromatography	chromatography	NN
cord-023443-pvz7dll9	698	20	and	and	CC
cord-023443-pvz7dll9	698	21	used	use	VBN
cord-023443-pvz7dll9	698	22	in	in	IN
cord-023443-pvz7dll9	698	23	subsequent	subsequent	JJ
cord-023443-pvz7dll9	698	24	binding	binding	NN
cord-023443-pvz7dll9	698	25	studies	study	NNS
cord-023443-pvz7dll9	698	26	resulting	result	VBG
cord-023443-pvz7dll9	698	27	in	in	IN
cord-023443-pvz7dll9	698	28	the	the	DT
cord-023443-pvz7dll9	698	29	determination	determination	NN
cord-023443-pvz7dll9	698	30	of	of	IN
cord-023443-pvz7dll9	698	31	KD	KD	NNP
cord-023443-pvz7dll9	698	32	for	for	IN
cord-023443-pvz7dll9	698	33	various	various	JJ
cord-023443-pvz7dll9	698	34	peptide	peptide	NN
cord-023443-pvz7dll9	698	35	ligands	ligand	NNS
cord-023443-pvz7dll9	698	36	ranging	range	VBG
cord-023443-pvz7dll9	698	37	from	from	IN
cord-023443-pvz7dll9	698	38	strong	strong	JJ
cord-023443-pvz7dll9	698	39	binders	binder	NNS
cord-023443-pvz7dll9	698	40	We	-PRON-	PRP
cord-023443-pvz7dll9	698	41	have	have	VBP
cord-023443-pvz7dll9	698	42	previously	previously	RB
cord-023443-pvz7dll9	698	43	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	698	44	that	that	IN
cord-023443-pvz7dll9	698	45	bioinformatics	bioinformatics	NN
cord-023443-pvz7dll9	698	46	tools	tool	NNS
cord-023443-pvz7dll9	698	47	such	such	JJ
cord-023443-pvz7dll9	698	48	as	as	IN
cord-023443-pvz7dll9	698	49	artificial	artificial	JJ
cord-023443-pvz7dll9	698	50	neural	neural	JJ
cord-023443-pvz7dll9	698	51	networks	network	NNS
cord-023443-pvz7dll9	698	52	(	(	-LRB-
cord-023443-pvz7dll9	698	53	ANNs	ANNs	NNP
cord-023443-pvz7dll9	698	54	)	)	-RRB-
cord-023443-pvz7dll9	698	55	are	be	VBP
cord-023443-pvz7dll9	698	56	capable	capable	JJ
cord-023443-pvz7dll9	698	57	of	of	IN
cord-023443-pvz7dll9	698	58	performing	perform	VBG
cord-023443-pvz7dll9	698	59	pathogen-	pathogen-	NN
cord-023443-pvz7dll9	698	60	,	,	,
cord-023443-pvz7dll9	698	61	genome	genome	NN
cord-023443-pvz7dll9	698	62	-	-	HYPH
cord-023443-pvz7dll9	698	63	and	and	CC
cord-023443-pvz7dll9	698	64	HLAwide	hlawide	NN
cord-023443-pvz7dll9	698	65	predictions	prediction	NNS
cord-023443-pvz7dll9	698	66	of	of	IN
cord-023443-pvz7dll9	698	67	peptide	peptide	NN
cord-023443-pvz7dll9	698	68	-	-	HYPH
cord-023443-pvz7dll9	698	69	HLA	HLA	NNP
cord-023443-pvz7dll9	698	70	interactions	interaction	NNS
cord-023443-pvz7dll9	698	71	.	.	.
cord-023443-pvz7dll9	699	1	These	these	DT
cord-023443-pvz7dll9	699	2	tools	tool	NNS
cord-023443-pvz7dll9	699	3	may	may	MD
cord-023443-pvz7dll9	699	4	therefore	therefore	RB
cord-023443-pvz7dll9	699	5	enable	enable	VB
cord-023443-pvz7dll9	699	6	a	a	DT
cord-023443-pvz7dll9	699	7	fast	fast	JJ
cord-023443-pvz7dll9	699	8	and	and	CC
cord-023443-pvz7dll9	699	9	rational	rational	JJ
cord-023443-pvz7dll9	699	10	approach	approach	NN
cord-023443-pvz7dll9	699	11	to	to	IN
cord-023443-pvz7dll9	699	12	epitope	epitope	NN
cord-023443-pvz7dll9	699	13	identification	identification	NN
cord-023443-pvz7dll9	699	14	and	and	CC
cord-023443-pvz7dll9	699	15	thereby	thereby	RB
cord-023443-pvz7dll9	699	16	assist	assist	VB
cord-023443-pvz7dll9	699	17	in	in	IN
cord-023443-pvz7dll9	699	18	the	the	DT
cord-023443-pvz7dll9	699	19	development	development	NN
cord-023443-pvz7dll9	699	20	of	of	IN
cord-023443-pvz7dll9	699	21	vaccines	vaccine	NNS
cord-023443-pvz7dll9	699	22	and	and	CC
cord-023443-pvz7dll9	699	23	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	699	24	.	.	.
cord-023443-pvz7dll9	700	1	A	a	DT
cord-023443-pvz7dll9	700	2	crucial	crucial	JJ
cord-023443-pvz7dll9	700	3	step	step	NN
cord-023443-pvz7dll9	700	4	in	in	IN
cord-023443-pvz7dll9	700	5	the	the	DT
cord-023443-pvz7dll9	700	6	generation	generation	NN
cord-023443-pvz7dll9	700	7	of	of	IN
cord-023443-pvz7dll9	700	8	such	such	JJ
cord-023443-pvz7dll9	700	9	bioinformatics	bioinformatics	NN
cord-023443-pvz7dll9	700	10	tools	tool	NNS
cord-023443-pvz7dll9	700	11	is	be	VBZ
cord-023443-pvz7dll9	700	12	the	the	DT
cord-023443-pvz7dll9	700	13	selection	selection	NN
cord-023443-pvz7dll9	700	14	of	of	IN
cord-023443-pvz7dll9	700	15	data	datum	NNS
cord-023443-pvz7dll9	700	16	representing	represent	VBG
cord-023443-pvz7dll9	700	17	the	the	DT
cord-023443-pvz7dll9	700	18	event	event	NN
cord-023443-pvz7dll9	700	19	in	in	IN
cord-023443-pvz7dll9	700	20	question	question	NN
cord-023443-pvz7dll9	700	21	(	(	-LRB-
cord-023443-pvz7dll9	700	22	in	in	IN
cord-023443-pvz7dll9	700	23	casu	casu	NNP
cord-023443-pvz7dll9	700	24	peptide	peptide	NNP
cord-023443-pvz7dll9	700	25	-	-	HYPH
cord-023443-pvz7dll9	700	26	HLA	HLA	NNP
cord-023443-pvz7dll9	700	27	interaction	interaction	NN
cord-023443-pvz7dll9	700	28	)	)	-RRB-
cord-023443-pvz7dll9	700	29	.	.	.
cord-023443-pvz7dll9	701	1	This	this	DT
cord-023443-pvz7dll9	701	2	is	be	VBZ
cord-023443-pvz7dll9	701	3	particularly	particularly	RB
cord-023443-pvz7dll9	701	4	important	important	JJ
cord-023443-pvz7dll9	701	5	when	when	WRB
cord-023443-pvz7dll9	701	6	it	-PRON-	PRP
cord-023443-pvz7dll9	701	7	is	be	VBZ
cord-023443-pvz7dll9	701	8	difficult	difficult	JJ
cord-023443-pvz7dll9	701	9	and	and	CC
cord-023443-pvz7dll9	701	10	expensive	expensive	JJ
cord-023443-pvz7dll9	701	11	to	to	TO
cord-023443-pvz7dll9	701	12	obtain	obtain	VB
cord-023443-pvz7dll9	701	13	data	datum	NNS
cord-023443-pvz7dll9	701	14	.	.	.
cord-023443-pvz7dll9	702	1	Herein	herein	RB
cord-023443-pvz7dll9	702	2	,	,	,
cord-023443-pvz7dll9	702	3	we	-PRON-	PRP
cord-023443-pvz7dll9	702	4	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	702	5	the	the	DT
cord-023443-pvz7dll9	702	6	importance	importance	NN
cord-023443-pvz7dll9	702	7	in	in	IN
cord-023443-pvz7dll9	702	8	selecting	select	VBG
cord-023443-pvz7dll9	702	9	information	information	NN
cord-023443-pvz7dll9	702	10	-	-	HYPH
cord-023443-pvz7dll9	702	11	rich	rich	JJ
cord-023443-pvz7dll9	702	12	data	datum	NNS
cord-023443-pvz7dll9	702	13	and	and	CC
cord-023443-pvz7dll9	702	14	we	-PRON-	PRP
cord-023443-pvz7dll9	702	15	develop	develop	VBP
cord-023443-pvz7dll9	702	16	a	a	DT
cord-023443-pvz7dll9	702	17	computational	computational	JJ
cord-023443-pvz7dll9	702	18	method	method	NN
cord-023443-pvz7dll9	702	19	,	,	,
cord-023443-pvz7dll9	702	20	query	query	NN
cord-023443-pvz7dll9	702	21	-	-	HYPH
cord-023443-pvz7dll9	702	22	bycommittee	bycommittee	NNP
cord-023443-pvz7dll9	702	23	,	,	,
cord-023443-pvz7dll9	702	24	which	which	WDT
cord-023443-pvz7dll9	702	25	can	can	MD
cord-023443-pvz7dll9	702	26	perform	perform	VB
cord-023443-pvz7dll9	702	27	a	a	DT
cord-023443-pvz7dll9	702	28	global	global	JJ
cord-023443-pvz7dll9	702	29	identification	identification	NN
cord-023443-pvz7dll9	702	30	of	of	IN
cord-023443-pvz7dll9	702	31	such	such	JJ
cord-023443-pvz7dll9	702	32	information	information	NN
cord-023443-pvz7dll9	702	33	-	-	HYPH
cord-023443-pvz7dll9	702	34	rich	rich	JJ
cord-023443-pvz7dll9	702	35	data	datum	NNS
cord-023443-pvz7dll9	702	36	in	in	IN
cord-023443-pvz7dll9	702	37	an	an	DT
cord-023443-pvz7dll9	702	38	unbiased	unbiased	JJ
cord-023443-pvz7dll9	702	39	and	and	CC
cord-023443-pvz7dll9	702	40	automated	automated	JJ
cord-023443-pvz7dll9	702	41	manner	manner	NN
cord-023443-pvz7dll9	702	42	.	.	.
cord-023443-pvz7dll9	703	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	703	2	,	,	,
cord-023443-pvz7dll9	703	3	we	-PRON-	PRP
cord-023443-pvz7dll9	703	4	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	703	5	how	how	WRB
cord-023443-pvz7dll9	703	6	this	this	DT
cord-023443-pvz7dll9	703	7	method	method	NN
cord-023443-pvz7dll9	703	8	can	can	MD
cord-023443-pvz7dll9	703	9	be	be	VB
cord-023443-pvz7dll9	703	10	applied	apply	VBN
cord-023443-pvz7dll9	703	11	to	to	IN
cord-023443-pvz7dll9	703	12	an	an	DT
cord-023443-pvz7dll9	703	13	efficient	efficient	JJ
cord-023443-pvz7dll9	703	14	iterative	iterative	JJ
cord-023443-pvz7dll9	703	15	development	development	NN
cord-023443-pvz7dll9	703	16	strategy	strategy	NN
cord-023443-pvz7dll9	703	17	for	for	IN
cord-023443-pvz7dll9	703	18	these	these	DT
cord-023443-pvz7dll9	703	19	bioinformatics	bioinformatics	NN
cord-023443-pvz7dll9	703	20	tools	tool	NNS
cord-023443-pvz7dll9	703	21	.	.	.
cord-023443-pvz7dll9	704	1	Methods	method	NNS
cord-023443-pvz7dll9	704	2	:	:	:
cord-023443-pvz7dll9	705	1	A	a	DT
cord-023443-pvz7dll9	705	2	large	large	JJ
cord-023443-pvz7dll9	705	3	panel	panel	NN
cord-023443-pvz7dll9	705	4	of	of	IN
cord-023443-pvz7dll9	705	5	binding	bind	VBG
cord-023443-pvz7dll9	705	6	affinities	affinity	NNS
cord-023443-pvz7dll9	705	7	of	of	IN
cord-023443-pvz7dll9	705	8	peptides	peptide	NNS
cord-023443-pvz7dll9	705	9	binding	bind	VBG
cord-023443-pvz7dll9	705	10	to	to	IN
cord-023443-pvz7dll9	705	11	HLA	HLA	NNP
cord-023443-pvz7dll9	705	12	A*0204	A*0204	NNP
cord-023443-pvz7dll9	705	13	was	be	VBD
cord-023443-pvz7dll9	705	14	measured	measure	VBN
cord-023443-pvz7dll9	705	15	by	by	IN
cord-023443-pvz7dll9	705	16	a	a	DT
cord-023443-pvz7dll9	705	17	radioimmunoassay	radioimmunoassay	JJ
cord-023443-pvz7dll9	705	18	(	(	-LRB-
cord-023443-pvz7dll9	705	19	RIA	RIA	NNP
cord-023443-pvz7dll9	705	20	)	)	-RRB-
cord-023443-pvz7dll9	705	21	.	.	.
cord-023443-pvz7dll9	706	1	This	this	DT
cord-023443-pvz7dll9	706	2	data	data	NN
cord-023443-pvz7dll9	706	3	was	be	VBD
cord-023443-pvz7dll9	706	4	used	use	VBN
cord-023443-pvz7dll9	706	5	to	to	TO
cord-023443-pvz7dll9	706	6	develop	develop	VB
cord-023443-pvz7dll9	706	7	multiple	multiple	JJ
cord-023443-pvz7dll9	706	8	first	first	JJ
cord-023443-pvz7dll9	706	9	generation	generation	NN
cord-023443-pvz7dll9	706	10	ANNs	ANNs	NNP
cord-023443-pvz7dll9	706	11	,	,	,
cord-023443-pvz7dll9	706	12	which	which	WDT
cord-023443-pvz7dll9	706	13	formed	form	VBD
cord-023443-pvz7dll9	706	14	a	a	DT
cord-023443-pvz7dll9	706	15	virtual	virtual	JJ
cord-023443-pvz7dll9	706	16	committee	committee	NN
cord-023443-pvz7dll9	706	17	.	.	.
cord-023443-pvz7dll9	707	1	This	this	DT
cord-023443-pvz7dll9	707	2	committee	committee	NN
cord-023443-pvz7dll9	707	3	was	be	VBD
cord-023443-pvz7dll9	707	4	used	use	VBN
cord-023443-pvz7dll9	707	5	to	to	TO
cord-023443-pvz7dll9	707	6	screen	screen	VB
cord-023443-pvz7dll9	707	7	(	(	-LRB-
cord-023443-pvz7dll9	707	8	or	or	CC
cord-023443-pvz7dll9	707	9	'	'	``
cord-023443-pvz7dll9	707	10	queried	query	VBN
cord-023443-pvz7dll9	707	11	'	'	''
cord-023443-pvz7dll9	707	12	)	)	-RRB-
cord-023443-pvz7dll9	707	13	for	for	IN
cord-023443-pvz7dll9	707	14	peptides	peptide	NNS
cord-023443-pvz7dll9	707	15	,	,	,
cord-023443-pvz7dll9	707	16	where	where	WRB
cord-023443-pvz7dll9	707	17	the	the	DT
cord-023443-pvz7dll9	707	18	ANNs	ANNs	NNP
cord-023443-pvz7dll9	707	19	agreed	agree	VBD
cord-023443-pvz7dll9	707	20	(	(	-LRB-
cord-023443-pvz7dll9	707	21	'	'	``
cord-023443-pvz7dll9	707	22	low	low	JJ
cord-023443-pvz7dll9	707	23	-	-	HYPH
cord-023443-pvz7dll9	707	24	QBC	QBC	NNP
cord-023443-pvz7dll9	707	25	'	'	''
cord-023443-pvz7dll9	707	26	)	)	-RRB-
cord-023443-pvz7dll9	707	27	,	,	,
cord-023443-pvz7dll9	707	28	or	or	CC
cord-023443-pvz7dll9	707	29	disagreed	disagree	VBN
cord-023443-pvz7dll9	707	30	(	(	-LRB-
cord-023443-pvz7dll9	707	31	'	'	``
cord-023443-pvz7dll9	707	32	high	high	JJ
cord-023443-pvz7dll9	707	33	-	-	HYPH
cord-023443-pvz7dll9	707	34	QBC	QBC	NNP
cord-023443-pvz7dll9	707	35	'	'	''
cord-023443-pvz7dll9	707	36	)	)	-RRB-
cord-023443-pvz7dll9	707	37	,	,	,
cord-023443-pvz7dll9	707	38	on	on	IN
cord-023443-pvz7dll9	707	39	their	-PRON-	PRP$
cord-023443-pvz7dll9	707	40	HLA	HLA	NNP
cord-023443-pvz7dll9	707	41	-	-	HYPH
cord-023443-pvz7dll9	707	42	binding	bind	VBG
cord-023443-pvz7dll9	707	43	potential	potential	NN
cord-023443-pvz7dll9	707	44	.	.	.
cord-023443-pvz7dll9	708	1	Seventeen	seventeen	CD
cord-023443-pvz7dll9	708	2	low	low	JJ
cord-023443-pvz7dll9	708	3	-	-	HYPH
cord-023443-pvz7dll9	708	4	QBC	QBC	NNP
cord-023443-pvz7dll9	708	5	peptides	peptide	NNS
cord-023443-pvz7dll9	708	6	and	and	CC
cord-023443-pvz7dll9	708	7	17	17	CD
cord-023443-pvz7dll9	708	8	high	high	JJ
cord-023443-pvz7dll9	708	9	-	-	HYPH
cord-023443-pvz7dll9	708	10	QBC	QBC	NNP
cord-023443-pvz7dll9	708	11	peptides	peptide	NNS
cord-023443-pvz7dll9	708	12	were	be	VBD
cord-023443-pvz7dll9	708	13	synthesized	synthesize	VBN
cord-023443-pvz7dll9	708	14	and	and	CC
cord-023443-pvz7dll9	708	15	tested	test	VBN
cord-023443-pvz7dll9	708	16	.	.	.
cord-023443-pvz7dll9	709	1	The	the	DT
cord-023443-pvz7dll9	709	2	high	high	JJ
cord-023443-pvz7dll9	709	3	-	-	HYPH
cord-023443-pvz7dll9	709	4	or	or	CC
cord-023443-pvz7dll9	709	5	low	low	JJ
cord-023443-pvz7dll9	709	6	-	-	HYPH
cord-023443-pvz7dll9	709	7	QBC	QBC	NNP
cord-023443-pvz7dll9	709	8	data	datum	NNS
cord-023443-pvz7dll9	709	9	were	be	VBD
cord-023443-pvz7dll9	709	10	added	add	VBN
cord-023443-pvz7dll9	709	11	to	to	IN
cord-023443-pvz7dll9	709	12	the	the	DT
cord-023443-pvz7dll9	709	13	original	original	JJ
cord-023443-pvz7dll9	709	14	data	datum	NNS
cord-023443-pvz7dll9	709	15	,	,	,
cord-023443-pvz7dll9	709	16	and	and	CC
cord-023443-pvz7dll9	709	17	new	new	JJ
cord-023443-pvz7dll9	709	18	high	high	JJ
cord-023443-pvz7dll9	709	19	-	-	HYPH
cord-023443-pvz7dll9	709	20	or	or	CC
cord-023443-pvz7dll9	709	21	low	low	JJ
cord-023443-pvz7dll9	709	22	-	-	HYPH
cord-023443-pvz7dll9	709	23	QBC	QBC	NNP
cord-023443-pvz7dll9	709	24	second	second	JJ
cord-023443-pvz7dll9	709	25	generation	generation	NN
cord-023443-pvz7dll9	709	26	ANNs	ANNs	NNPS
cord-023443-pvz7dll9	709	27	were	be	VBD
cord-023443-pvz7dll9	709	28	developed	develop	VBN
cord-023443-pvz7dll9	709	29	,	,	,
cord-023443-pvz7dll9	709	30	respectively	respectively	RB
cord-023443-pvz7dll9	709	31	.	.	.
cord-023443-pvz7dll9	710	1	This	this	DT
cord-023443-pvz7dll9	710	2	procedure	procedure	NN
cord-023443-pvz7dll9	710	3	was	be	VBD
cord-023443-pvz7dll9	710	4	repeated	repeat	VBN
cord-023443-pvz7dll9	710	5	40	40	CD
cord-023443-pvz7dll9	710	6	times	time	NNS
cord-023443-pvz7dll9	710	7	.	.	.
cord-023443-pvz7dll9	711	1	The	the	DT
cord-023443-pvz7dll9	711	2	high	high	JJ
cord-023443-pvz7dll9	711	3	-	-	HYPH
cord-023443-pvz7dll9	711	4	QBC	qbc	NN
cord-023443-pvz7dll9	711	5	-	-	HYPH
cord-023443-pvz7dll9	711	6	enriched	enrich	VBN
cord-023443-pvz7dll9	711	7	ANN	ANN	NNP
cord-023443-pvz7dll9	711	8	performed	perform	VBD
cord-023443-pvz7dll9	711	9	significantly	significantly	RB
cord-023443-pvz7dll9	711	10	better	well	RBR
cord-023443-pvz7dll9	711	11	than	than	IN
cord-023443-pvz7dll9	711	12	the	the	DT
cord-023443-pvz7dll9	711	13	low	low	JJ
cord-023443-pvz7dll9	711	14	-	-	HYPH
cord-023443-pvz7dll9	711	15	QBC	qbc	NN
cord-023443-pvz7dll9	711	16	-	-	HYPH
cord-023443-pvz7dll9	711	17	enriched	enrich	VBN
cord-023443-pvz7dll9	711	18	ANN	ANN	NNP
cord-023443-pvz7dll9	711	19	in	in	IN
cord-023443-pvz7dll9	711	20	37	37	CD
cord-023443-pvz7dll9	711	21	of	of	IN
cord-023443-pvz7dll9	711	22	the	the	DT
cord-023443-pvz7dll9	711	23	40	40	CD
cord-023443-pvz7dll9	711	24	tests	test	NNS
cord-023443-pvz7dll9	711	25	.	.	.
cord-023443-pvz7dll9	712	1	Conclusion	conclusion	NN
cord-023443-pvz7dll9	712	2	:	:	:
cord-023443-pvz7dll9	713	1	These	these	DT
cord-023443-pvz7dll9	713	2	results	result	NNS
cord-023443-pvz7dll9	713	3	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	713	4	that	that	IN
cord-023443-pvz7dll9	713	5	high	high	JJ
cord-023443-pvz7dll9	713	6	-	-	HYPH
cord-023443-pvz7dll9	713	7	QBCenriched	qbcenriched	NN
cord-023443-pvz7dll9	713	8	networks	network	NNS
cord-023443-pvz7dll9	713	9	perform	perform	VBP
cord-023443-pvz7dll9	713	10	better	well	JJR
cord-023443-pvz7dll9	713	11	than	than	IN
cord-023443-pvz7dll9	713	12	low	low	JJ
cord-023443-pvz7dll9	713	13	-	-	HYPH
cord-023443-pvz7dll9	713	14	QBC	qbc	NN
cord-023443-pvz7dll9	713	15	-	-	HYPH
cord-023443-pvz7dll9	713	16	enriched	enrich	VBN
cord-023443-pvz7dll9	713	17	networks	network	NNS
cord-023443-pvz7dll9	713	18	in	in	IN
cord-023443-pvz7dll9	713	19	selecting	select	VBG
cord-023443-pvz7dll9	713	20	informative	informative	JJ
cord-023443-pvz7dll9	713	21	data	datum	NNS
cord-023443-pvz7dll9	713	22	for	for	IN
cord-023443-pvz7dll9	713	23	developing	develop	VBG
cord-023443-pvz7dll9	713	24	peptide	peptide	JJ
cord-023443-pvz7dll9	713	25	-	-	HYPH
cord-023443-pvz7dll9	713	26	MHC	MHC	NNP
cord-023443-pvz7dll9	713	27	-	-	HYPH
cord-023443-pvz7dll9	713	28	binding	bind	VBG
cord-023443-pvz7dll9	713	29	predictors	predictor	NNS
cord-023443-pvz7dll9	713	30	.	.	.
cord-023443-pvz7dll9	714	1	This	this	DT
cord-023443-pvz7dll9	714	2	improvement	improvement	NN
cord-023443-pvz7dll9	714	3	in	in	IN
cord-023443-pvz7dll9	714	4	selecting	select	VBG
cord-023443-pvz7dll9	714	5	data	datum	NNS
cord-023443-pvz7dll9	714	6	is	be	VBZ
cord-023443-pvz7dll9	714	7	not	not	RB
cord-023443-pvz7dll9	714	8	due	due	JJ
cord-023443-pvz7dll9	714	9	to	to	IN
cord-023443-pvz7dll9	714	10	differences	difference	NNS
cord-023443-pvz7dll9	714	11	in	in	IN
cord-023443-pvz7dll9	714	12	network	network	NN
cord-023443-pvz7dll9	714	13	training	training	NN
cord-023443-pvz7dll9	714	14	performance	performance	NN
cord-023443-pvz7dll9	714	15	but	but	CC
cord-023443-pvz7dll9	714	16	due	due	IN
cord-023443-pvz7dll9	714	17	to	to	IN
cord-023443-pvz7dll9	714	18	the	the	DT
cord-023443-pvz7dll9	714	19	difference	difference	NN
cord-023443-pvz7dll9	714	20	in	in	IN
cord-023443-pvz7dll9	714	21	information	information	NN
cord-023443-pvz7dll9	714	22	content	content	NN
cord-023443-pvz7dll9	714	23	in	in	IN
cord-023443-pvz7dll9	714	24	the	the	DT
cord-023443-pvz7dll9	714	25	high	high	JJ
cord-023443-pvz7dll9	714	26	-	-	HYPH
cord-023443-pvz7dll9	714	27	QBC	QBC	NNP
cord-023443-pvz7dll9	714	28	experiment	experiment	NN
cord-023443-pvz7dll9	714	29	and	and	CC
cord-023443-pvz7dll9	714	30	in	in	IN
cord-023443-pvz7dll9	714	31	the	the	DT
cord-023443-pvz7dll9	714	32	low	low	JJ
cord-023443-pvz7dll9	714	33	-	-	HYPH
cord-023443-pvz7dll9	714	34	QBC	QBC	NNP
cord-023443-pvz7dll9	714	35	experiment	experiment	NN
cord-023443-pvz7dll9	714	36	.	.	.
cord-023443-pvz7dll9	715	1	Finally	finally	RB
cord-023443-pvz7dll9	715	2	,	,	,
cord-023443-pvz7dll9	715	3	it	-PRON-	PRP
cord-023443-pvz7dll9	715	4	should	should	MD
cord-023443-pvz7dll9	715	5	be	be	VB
cord-023443-pvz7dll9	715	6	noted	note	VBN
cord-023443-pvz7dll9	715	7	that	that	IN
cord-023443-pvz7dll9	715	8	this	this	DT
cord-023443-pvz7dll9	715	9	strategy	strategy	NN
cord-023443-pvz7dll9	715	10	could	could	MD
cord-023443-pvz7dll9	715	11	be	be	VB
cord-023443-pvz7dll9	715	12	used	use	VBN
cord-023443-pvz7dll9	715	13	in	in	IN
cord-023443-pvz7dll9	715	14	many	many	JJ
cord-023443-pvz7dll9	715	15	contexts	context	NNS
cord-023443-pvz7dll9	715	16	where	where	WRB
cord-023443-pvz7dll9	715	17	generation	generation	NN
cord-023443-pvz7dll9	715	18	of	of	IN
cord-023443-pvz7dll9	715	19	data	datum	NNS
cord-023443-pvz7dll9	715	20	is	be	VBZ
cord-023443-pvz7dll9	715	21	difficult	difficult	JJ
cord-023443-pvz7dll9	715	22	and	and	CC
cord-023443-pvz7dll9	715	23	costly	costly	JJ
cord-023443-pvz7dll9	715	24	.	.	.
cord-023443-pvz7dll9	716	1	Interleukin-18	Interleukin-18	NNP
cord-023443-pvz7dll9	716	2	(	(	-LRB-
cord-023443-pvz7dll9	716	3	IL-18	IL-18	NNP
cord-023443-pvz7dll9	716	4	)	)	-RRB-
cord-023443-pvz7dll9	716	5	,	,	,
cord-023443-pvz7dll9	716	6	a	a	DT
cord-023443-pvz7dll9	716	7	pro	pro	JJ
cord-023443-pvz7dll9	716	8	-	-	JJ
cord-023443-pvz7dll9	716	9	inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	716	10	cytokine	cytokine	NN
cord-023443-pvz7dll9	716	11	that	that	WDT
cord-023443-pvz7dll9	716	12	is	be	VBZ
cord-023443-pvz7dll9	716	13	produced	produce	VBN
cord-023443-pvz7dll9	716	14	by	by	IN
cord-023443-pvz7dll9	716	15	both	both	DT
cord-023443-pvz7dll9	716	16	lymphoid	lymphoid	NNP
cord-023443-pvz7dll9	716	17	and	and	CC
cord-023443-pvz7dll9	716	18	nonlymphoid	nonlymphoid	NNP
cord-023443-pvz7dll9	716	19	cells	cell	NNS
cord-023443-pvz7dll9	716	20	,	,	,
cord-023443-pvz7dll9	716	21	has	have	VBZ
cord-023443-pvz7dll9	716	22	a	a	DT
cord-023443-pvz7dll9	716	23	critical	critical	JJ
cord-023443-pvz7dll9	716	24	role	role	NN
cord-023443-pvz7dll9	716	25	in	in	IN
cord-023443-pvz7dll9	716	26	modulation	modulation	NN
cord-023443-pvz7dll9	716	27	of	of	IN
cord-023443-pvz7dll9	716	28	innate	innate	JJ
cord-023443-pvz7dll9	716	29	and	and	CC
cord-023443-pvz7dll9	716	30	adaptive	adaptive	JJ
cord-023443-pvz7dll9	716	31	immunity	immunity	NN
cord-023443-pvz7dll9	716	32	.	.	.
cord-023443-pvz7dll9	717	1	Its	-PRON-	PRP$
cord-023443-pvz7dll9	717	2	primary	primary	JJ
cord-023443-pvz7dll9	717	3	function	function	NN
cord-023443-pvz7dll9	717	4	in	in	IN
cord-023443-pvz7dll9	717	5	stimulation	stimulation	NN
cord-023443-pvz7dll9	717	6	of	of	IN
cord-023443-pvz7dll9	717	7	IFN	IFN	NNP
cord-023443-pvz7dll9	717	8	-	-	HYPH
cord-023443-pvz7dll9	717	9	g	g	NN
cord-023443-pvz7dll9	717	10	production	production	NN
cord-023443-pvz7dll9	717	11	and	and	CC
cord-023443-pvz7dll9	717	12	stimulation	stimulation	NN
cord-023443-pvz7dll9	717	13	of	of	IN
cord-023443-pvz7dll9	717	14	NK	nk	NN
cord-023443-pvz7dll9	717	15	-	-	HYPH
cord-023443-pvz7dll9	717	16	cell	cell	NN
cord-023443-pvz7dll9	717	17	-	-	HYPH
cord-023443-pvz7dll9	717	18	cytotoxic	cytotoxic	JJ
cord-023443-pvz7dll9	717	19	activities	activity	NNS
cord-023443-pvz7dll9	717	20	makes	make	VBZ
cord-023443-pvz7dll9	717	21	this	this	DT
cord-023443-pvz7dll9	717	22	cytokine	cytokine	NN
cord-023443-pvz7dll9	717	23	a	a	DT
cord-023443-pvz7dll9	717	24	candidate	candidate	NN
cord-023443-pvz7dll9	717	25	for	for	IN
cord-023443-pvz7dll9	717	26	cancer	cancer	NN
cord-023443-pvz7dll9	717	27	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	717	28	.	.	.
cord-023443-pvz7dll9	718	1	In	in	IN
cord-023443-pvz7dll9	718	2	oral	oral	JJ
cord-023443-pvz7dll9	718	3	cavity	cavity	NN
cord-023443-pvz7dll9	718	4	,	,	,
cord-023443-pvz7dll9	718	5	this	this	DT
cord-023443-pvz7dll9	718	6	cytokine	cytokine	NN
cord-023443-pvz7dll9	718	7	is	be	VBZ
cord-023443-pvz7dll9	718	8	produced	produce	VBN
cord-023443-pvz7dll9	718	9	by	by	IN
cord-023443-pvz7dll9	718	10	oral	oral	JJ
cord-023443-pvz7dll9	718	11	epithelia	epithelium	NNS
cord-023443-pvz7dll9	718	12	and	and	CC
cord-023443-pvz7dll9	718	13	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	718	14	cells	cell	NNS
cord-023443-pvz7dll9	718	15	and	and	CC
cord-023443-pvz7dll9	718	16	is	be	VBZ
cord-023443-pvz7dll9	718	17	related	relate	VBN
cord-023443-pvz7dll9	718	18	to	to	IN
cord-023443-pvz7dll9	718	19	tumour	tumour	NN
cord-023443-pvz7dll9	718	20	regression	regression	NN
cord-023443-pvz7dll9	718	21	in	in	IN
cord-023443-pvz7dll9	718	22	nude	nude	JJ
cord-023443-pvz7dll9	718	23	mice	mouse	NNS
cord-023443-pvz7dll9	718	24	bearing	bear	VBG
cord-023443-pvz7dll9	718	25	salivary	salivary	JJ
cord-023443-pvz7dll9	718	26	adenocarcinoma	adenocarcinoma	NN
cord-023443-pvz7dll9	718	27	.	.	.
cord-023443-pvz7dll9	719	1	However	however	RB
cord-023443-pvz7dll9	719	2	,	,	,
cord-023443-pvz7dll9	719	3	direct	direct	JJ
cord-023443-pvz7dll9	719	4	effects	effect	NNS
cord-023443-pvz7dll9	719	5	of	of	IN
cord-023443-pvz7dll9	719	6	this	this	DT
cord-023443-pvz7dll9	719	7	cytokine	cytokine	NN
cord-023443-pvz7dll9	719	8	on	on	IN
cord-023443-pvz7dll9	719	9	oral	oral	JJ
cord-023443-pvz7dll9	719	10	cancer	cancer	NN
cord-023443-pvz7dll9	719	11	cells	cell	NNS
cord-023443-pvz7dll9	719	12	have	have	VBP
cord-023443-pvz7dll9	719	13	not	not	RB
cord-023443-pvz7dll9	719	14	been	be	VBN
cord-023443-pvz7dll9	719	15	elucidated	elucidate	VBN
cord-023443-pvz7dll9	719	16	.	.	.
cord-023443-pvz7dll9	720	1	In	in	IN
cord-023443-pvz7dll9	720	2	this	this	DT
cord-023443-pvz7dll9	720	3	project	project	NN
cord-023443-pvz7dll9	720	4	,	,	,
cord-023443-pvz7dll9	720	5	we	-PRON-	PRP
cord-023443-pvz7dll9	720	6	investigated	investigate	VBD
cord-023443-pvz7dll9	720	7	IL-18	IL-18	NNP
cord-023443-pvz7dll9	720	8	effect	effect	NN
cord-023443-pvz7dll9	720	9	on	on	IN
cord-023443-pvz7dll9	720	10	an	an	DT
cord-023443-pvz7dll9	720	11	oral	oral	JJ
cord-023443-pvz7dll9	720	12	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	720	13	(	(	-LRB-
cord-023443-pvz7dll9	720	14	KB	KB	NNP
cord-023443-pvz7dll9	720	15	)	)	-RRB-
cord-023443-pvz7dll9	720	16	cell	cell	NN
cord-023443-pvz7dll9	720	17	line	line	NN
cord-023443-pvz7dll9	720	18	.	.	.
cord-023443-pvz7dll9	721	1	With	with	IN
cord-023443-pvz7dll9	721	2	RT	RT	NNP
cord-023443-pvz7dll9	721	3	-	-	HYPH
cord-023443-pvz7dll9	721	4	PCR	PCR	NNP
cord-023443-pvz7dll9	721	5	technique	technique	NN
cord-023443-pvz7dll9	721	6	,	,	,
cord-023443-pvz7dll9	721	7	KB	kb	NN
cord-023443-pvz7dll9	721	8	-	-	HYPH
cord-023443-pvz7dll9	721	9	cell	cell	NN
cord-023443-pvz7dll9	721	10	line	line	NN
cord-023443-pvz7dll9	721	11	was	be	VBD
cord-023443-pvz7dll9	721	12	found	find	VBN
cord-023443-pvz7dll9	721	13	to	to	TO
cord-023443-pvz7dll9	721	14	express	express	VB
cord-023443-pvz7dll9	721	15	IL-18	IL-18	NNP
cord-023443-pvz7dll9	721	16	receptors	receptor	NNS
cord-023443-pvz7dll9	721	17	(	(	-LRB-
cord-023443-pvz7dll9	721	18	IL-18Ra	IL-18Ra	NNP
cord-023443-pvz7dll9	721	19	and	and	CC
cord-023443-pvz7dll9	721	20	IL-18Rb	IL-18Rb	NNP
cord-023443-pvz7dll9	721	21	)	)	-RRB-
cord-023443-pvz7dll9	721	22	,	,	,
cord-023443-pvz7dll9	721	23	indicating	indicate	VBG
cord-023443-pvz7dll9	721	24	that	that	IN
cord-023443-pvz7dll9	721	25	this	this	DT
cord-023443-pvz7dll9	721	26	oral	oral	JJ
cord-023443-pvz7dll9	721	27	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	721	28	line	line	NN
cord-023443-pvz7dll9	721	29	is	be	VBZ
cord-023443-pvz7dll9	721	30	a	a	DT
cord-023443-pvz7dll9	721	31	target	target	NN
cord-023443-pvz7dll9	721	32	for	for	IN
cord-023443-pvz7dll9	721	33	IL-18	IL-18	NNP
cord-023443-pvz7dll9	721	34	study	study	NN
cord-023443-pvz7dll9	721	35	.	.	.
cord-023443-pvz7dll9	722	1	We	-PRON-	PRP
cord-023443-pvz7dll9	722	2	showed	show	VBD
cord-023443-pvz7dll9	722	3	that	that	IN
cord-023443-pvz7dll9	722	4	recombinant	recombinant	JJ
cord-023443-pvz7dll9	722	5	human	human	NN
cord-023443-pvz7dll9	722	6	IL-18	IL-18	NNP
cord-023443-pvz7dll9	722	7	inhibited	inhibited	JJ
cord-023443-pvz7dll9	722	8	KB	KB	NNP
cord-023443-pvz7dll9	722	9	-	-	HYPH
cord-023443-pvz7dll9	722	10	cell	cell	NN
cord-023443-pvz7dll9	722	11	proliferation	proliferation	NN
cord-023443-pvz7dll9	722	12	by	by	IN
cord-023443-pvz7dll9	722	13	17	17	CD
cord-023443-pvz7dll9	722	14	%	%	NN
cord-023443-pvz7dll9	722	15	at	at	IN
cord-023443-pvz7dll9	722	16	concentration	concentration	NN
cord-023443-pvz7dll9	722	17	of	of	IN
cord-023443-pvz7dll9	722	18	100	100	CD
cord-023443-pvz7dll9	722	19	ng	ng	NN
cord-023443-pvz7dll9	722	20	/	/	SYM
cord-023443-pvz7dll9	722	21	ml	ml	NN
cord-023443-pvz7dll9	722	22	(	(	-LRB-
cord-023443-pvz7dll9	722	23	P	p	NN
cord-023443-pvz7dll9	722	24	<	<	XX
cord-023443-pvz7dll9	722	25	0.05	0.05	CD
cord-023443-pvz7dll9	722	26	)	)	-RRB-
cord-023443-pvz7dll9	722	27	,	,	,
cord-023443-pvz7dll9	722	28	whereas	whereas	IN
cord-023443-pvz7dll9	722	29	LDH	LDH	NNP
cord-023443-pvz7dll9	722	30	release	release	NN
cord-023443-pvz7dll9	722	31	by	by	IN
cord-023443-pvz7dll9	722	32	these	these	DT
cord-023443-pvz7dll9	722	33	cells	cell	NNS
cord-023443-pvz7dll9	722	34	in	in	IN
cord-023443-pvz7dll9	722	35	treatment	treatment	NN
cord-023443-pvz7dll9	722	36	group	group	NN
cord-023443-pvz7dll9	722	37	and	and	CC
cord-023443-pvz7dll9	722	38	control	control	NN
cord-023443-pvz7dll9	722	39	groups	group	NNS
cord-023443-pvz7dll9	722	40	was	be	VBD
cord-023443-pvz7dll9	722	41	comparable	comparable	JJ
cord-023443-pvz7dll9	722	42	,	,	,
cord-023443-pvz7dll9	722	43	indicating	indicate	VBG
cord-023443-pvz7dll9	722	44	that	that	IN
cord-023443-pvz7dll9	722	45	IL-18	IL-18	NNP
cord-023443-pvz7dll9	722	46	suppression	suppression	NN
cord-023443-pvz7dll9	722	47	of	of	IN
cord-023443-pvz7dll9	722	48	cell	cell	NN
cord-023443-pvz7dll9	722	49	proliferation	proliferation	NN
cord-023443-pvz7dll9	722	50	was	be	VBD
cord-023443-pvz7dll9	722	51	not	not	RB
cord-023443-pvz7dll9	722	52	mediated	mediate	VBN
cord-023443-pvz7dll9	722	53	by	by	IN
cord-023443-pvz7dll9	722	54	the	the	DT
cord-023443-pvz7dll9	722	55	induction	induction	NN
cord-023443-pvz7dll9	722	56	of	of	IN
cord-023443-pvz7dll9	722	57	cell	cell	NN
cord-023443-pvz7dll9	722	58	death	death	NN
cord-023443-pvz7dll9	722	59	.	.	.
cord-023443-pvz7dll9	723	1	To	to	TO
cord-023443-pvz7dll9	723	2	further	further	RB
cord-023443-pvz7dll9	723	3	address	address	VB
cord-023443-pvz7dll9	723	4	this	this	DT
cord-023443-pvz7dll9	723	5	hypothesis	hypothesis	NN
cord-023443-pvz7dll9	723	6	,	,	,
cord-023443-pvz7dll9	723	7	we	-PRON-	PRP
cord-023443-pvz7dll9	723	8	found	find	VBD
cord-023443-pvz7dll9	723	9	that	that	IN
cord-023443-pvz7dll9	723	10	IL-18	IL-18	NNP
cord-023443-pvz7dll9	723	11	treatment	treatment	NN
cord-023443-pvz7dll9	723	12	did	do	VBD
cord-023443-pvz7dll9	723	13	not	not	RB
cord-023443-pvz7dll9	723	14	induce	induce	VB
cord-023443-pvz7dll9	723	15	apoptotic	apoptotic	JJ
cord-023443-pvz7dll9	723	16	cell	cell	NN
cord-023443-pvz7dll9	723	17	death	death	NN
cord-023443-pvz7dll9	723	18	,	,	,
cord-023443-pvz7dll9	723	19	as	as	IN
cord-023443-pvz7dll9	723	20	studied	study	VBN
cord-023443-pvz7dll9	723	21	by	by	IN
cord-023443-pvz7dll9	723	22	DNA	dna	NN
cord-023443-pvz7dll9	723	23	laddering	laddering	NN
cord-023443-pvz7dll9	723	24	and	and	CC
cord-023443-pvz7dll9	723	25	TUNEL	TUNEL	NNP
cord-023443-pvz7dll9	723	26	assays	assay	NNS
cord-023443-pvz7dll9	723	27	.	.	.
cord-023443-pvz7dll9	724	1	In	in	IN
cord-023443-pvz7dll9	724	2	addition	addition	NN
cord-023443-pvz7dll9	724	3	,	,	,
cord-023443-pvz7dll9	724	4	expression	expression	NN
cord-023443-pvz7dll9	724	5	pattern	pattern	NN
cord-023443-pvz7dll9	724	6	of	of	IN
cord-023443-pvz7dll9	724	7	cell	cell	NN
cord-023443-pvz7dll9	724	8	death	death	NN
cord-023443-pvz7dll9	724	9	-	-	HYPH
cord-023443-pvz7dll9	724	10	controlling	control	VBG
cord-023443-pvz7dll9	724	11	genes	gene	NNS
cord-023443-pvz7dll9	724	12	(	(	-LRB-
cord-023443-pvz7dll9	724	13	bcl-2	bcl-2	NNP
cord-023443-pvz7dll9	724	14	and	and	CC
cord-023443-pvz7dll9	724	15	bax	bax	NNP
cord-023443-pvz7dll9	724	16	)	)	-RRB-
cord-023443-pvz7dll9	724	17	was	be	VBD
cord-023443-pvz7dll9	724	18	not	not	RB
cord-023443-pvz7dll9	724	19	altered	alter	VBN
cord-023443-pvz7dll9	724	20	by	by	IN
cord-023443-pvz7dll9	724	21	this	this	DT
cord-023443-pvz7dll9	724	22	cytokine	cytokine	NN
cord-023443-pvz7dll9	724	23	.	.	.
cord-023443-pvz7dll9	725	1	Findings	finding	NNS
cord-023443-pvz7dll9	725	2	in	in	IN
cord-023443-pvz7dll9	725	3	these	these	DT
cord-023443-pvz7dll9	725	4	studies	study	NNS
cord-023443-pvz7dll9	725	5	indicated	indicate	VBD
cord-023443-pvz7dll9	725	6	that	that	IN
cord-023443-pvz7dll9	725	7	suppression	suppression	NN
cord-023443-pvz7dll9	725	8	of	of	IN
cord-023443-pvz7dll9	725	9	KB	kb	NN
cord-023443-pvz7dll9	725	10	-	-	HYPH
cord-023443-pvz7dll9	725	11	cell	cell	NN
cord-023443-pvz7dll9	725	12	proliferation	proliferation	NN
cord-023443-pvz7dll9	725	13	may	may	MD
cord-023443-pvz7dll9	725	14	be	be	VB
cord-023443-pvz7dll9	725	15	attributed	attribute	VBN
cord-023443-pvz7dll9	725	16	to	to	IN
cord-023443-pvz7dll9	725	17	control	control	NN
cord-023443-pvz7dll9	725	18	of	of	IN
cord-023443-pvz7dll9	725	19	cell	cell	NN
cord-023443-pvz7dll9	725	20	cycle	cycle	NN
cord-023443-pvz7dll9	725	21	,	,	,
cord-023443-pvz7dll9	725	22	growth	growth	NN
cord-023443-pvz7dll9	725	23	arrest	arrest	NN
cord-023443-pvz7dll9	725	24	or	or	CC
cord-023443-pvz7dll9	725	25	induction	induction	NN
cord-023443-pvz7dll9	725	26	of	of	IN
cord-023443-pvz7dll9	725	27	cell	cell	NN
cord-023443-pvz7dll9	725	28	differentiation	differentiation	NN
cord-023443-pvz7dll9	725	29	.	.	.
cord-023443-pvz7dll9	726	1	The	the	DT
cord-023443-pvz7dll9	726	2	data	datum	NNS
cord-023443-pvz7dll9	726	3	presented	present	VBN
cord-023443-pvz7dll9	726	4	in	in	IN
cord-023443-pvz7dll9	726	5	this	this	DT
cord-023443-pvz7dll9	726	6	project	project	NN
cord-023443-pvz7dll9	726	7	could	could	MD
cord-023443-pvz7dll9	726	8	provide	provide	VB
cord-023443-pvz7dll9	726	9	an	an	DT
cord-023443-pvz7dll9	726	10	insight	insight	NN
cord-023443-pvz7dll9	726	11	of	of	IN
cord-023443-pvz7dll9	726	12	how	how	WRB
cord-023443-pvz7dll9	726	13	cancer	cancer	NN
cord-023443-pvz7dll9	726	14	cell	cell	NN
cord-023443-pvz7dll9	726	15	directly	directly	RB
cord-023443-pvz7dll9	726	16	responds	respond	VBZ
cord-023443-pvz7dll9	726	17	to	to	IN
cord-023443-pvz7dll9	726	18	IL-18	IL-18	NNP
cord-023443-pvz7dll9	726	19	,	,	,
cord-023443-pvz7dll9	726	20	as	as	IN
cord-023443-pvz7dll9	726	21	this	this	DT
cord-023443-pvz7dll9	726	22	cytokine	cytokine	NN
cord-023443-pvz7dll9	726	23	is	be	VBZ
cord-023443-pvz7dll9	726	24	an	an	DT
cord-023443-pvz7dll9	726	25	important	important	JJ
cord-023443-pvz7dll9	726	26	regulator	regulator	NN
cord-023443-pvz7dll9	726	27	of	of	IN
cord-023443-pvz7dll9	726	28	anticancer	anticancer	JJ
cord-023443-pvz7dll9	726	29	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	726	30	.	.	.
cord-023443-pvz7dll9	727	1	Aloe	aloe	NN
cord-023443-pvz7dll9	727	2	emodin	emodin	NNS
cord-023443-pvz7dll9	727	3	(	(	-LRB-
cord-023443-pvz7dll9	727	4	AE	AE	NNP
cord-023443-pvz7dll9	727	5	)	)	-RRB-
cord-023443-pvz7dll9	727	6	is	be	VBZ
cord-023443-pvz7dll9	727	7	a	a	DT
cord-023443-pvz7dll9	727	8	naturally	naturally	RB
cord-023443-pvz7dll9	727	9	occurring	occur	VBG
cord-023443-pvz7dll9	727	10	compound	compound	NN
cord-023443-pvz7dll9	727	11	with	with	IN
cord-023443-pvz7dll9	727	12	wide	wide	JJ
cord-023443-pvz7dll9	727	13	spectrum	spectrum	NN
cord-023443-pvz7dll9	727	14	of	of	IN
cord-023443-pvz7dll9	727	15	biological	biological	JJ
cord-023443-pvz7dll9	727	16	properties	property	NNS
cord-023443-pvz7dll9	727	17	,	,	,
cord-023443-pvz7dll9	727	18	including	include	VBG
cord-023443-pvz7dll9	727	19	antimicrobial	antimicrobial	JJ
cord-023443-pvz7dll9	727	20	,	,	,
cord-023443-pvz7dll9	727	21	vasorelaxant	vasorelaxant	JJ
cord-023443-pvz7dll9	727	22	,	,	,
cord-023443-pvz7dll9	727	23	immunosuppressive	immunosuppressive	JJ
cord-023443-pvz7dll9	727	24	and	and	CC
cord-023443-pvz7dll9	727	25	anticancer	anticancer	JJ
cord-023443-pvz7dll9	727	26	actions	action	NNS
cord-023443-pvz7dll9	727	27	.	.	.
cord-023443-pvz7dll9	728	1	This	this	DT
cord-023443-pvz7dll9	728	2	anthraquinone	anthraquinone	NN
cord-023443-pvz7dll9	728	3	induces	induce	VBZ
cord-023443-pvz7dll9	728	4	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	728	5	in	in	IN
cord-023443-pvz7dll9	728	6	several	several	JJ
cord-023443-pvz7dll9	728	7	tumour	tumour	NN
cord-023443-pvz7dll9	728	8	cell	cell	NN
cord-023443-pvz7dll9	728	9	lines	line	NNS
cord-023443-pvz7dll9	728	10	with	with	IN
cord-023443-pvz7dll9	728	11	special	special	JJ
cord-023443-pvz7dll9	728	12	affinity	affinity	NN
cord-023443-pvz7dll9	728	13	to	to	IN
cord-023443-pvz7dll9	728	14	tumours	tumour	NNS
cord-023443-pvz7dll9	728	15	of	of	IN
cord-023443-pvz7dll9	728	16	neuroectodermal	neuroectodermal	JJ
cord-023443-pvz7dll9	728	17	origin	origin	NN
cord-023443-pvz7dll9	728	18	.	.	.
cord-023443-pvz7dll9	729	1	High	high	JJ
cord-023443-pvz7dll9	729	2	amounts	amount	NNS
cord-023443-pvz7dll9	729	3	of	of	IN
cord-023443-pvz7dll9	729	4	nitric	nitric	NN
cord-023443-pvz7dll9	729	5	oxide	oxide	NN
cord-023443-pvz7dll9	729	6	(	(	-LRB-
cord-023443-pvz7dll9	729	7	NO	no	RB
cord-023443-pvz7dll9	729	8	)	)	-RRB-
cord-023443-pvz7dll9	729	9	released	release	VBN
cord-023443-pvz7dll9	729	10	by	by	IN
cord-023443-pvz7dll9	729	11	activated	activate	VBN
cord-023443-pvz7dll9	729	12	macrophages	macrophage	NNS
cord-023443-pvz7dll9	729	13	induce	induce	VBP
cord-023443-pvz7dll9	729	14	tumour	tumour	NN
cord-023443-pvz7dll9	729	15	cell	cell	NN
cord-023443-pvz7dll9	729	16	death	death	NN
cord-023443-pvz7dll9	729	17	.	.	.
cord-023443-pvz7dll9	730	1	Therefore	therefore	RB
cord-023443-pvz7dll9	730	2	,	,	,
cord-023443-pvz7dll9	730	3	we	-PRON-	PRP
cord-023443-pvz7dll9	730	4	explored	explore	VBD
cord-023443-pvz7dll9	730	5	the	the	DT
cord-023443-pvz7dll9	730	6	capacity	capacity	NN
cord-023443-pvz7dll9	730	7	of	of	IN
cord-023443-pvz7dll9	730	8	AE	AE	NNP
cord-023443-pvz7dll9	730	9	to	to	TO
cord-023443-pvz7dll9	730	10	modulate	modulate	VB
cord-023443-pvz7dll9	730	11	NO	no	RB
cord-023443-pvz7dll9	730	12	-	-	HYPH
cord-023443-pvz7dll9	730	13	mediated	mediate	VBN
cord-023443-pvz7dll9	730	14	antitumour	antitumour	JJ
cord-023443-pvz7dll9	730	15	response	response	NN
cord-023443-pvz7dll9	730	16	in	in	IN
cord-023443-pvz7dll9	730	17	vitro	vitro	FW
cord-023443-pvz7dll9	730	18	.	.	.
cord-023443-pvz7dll9	731	1	Interestingly	interestingly	RB
cord-023443-pvz7dll9	731	2	,	,	,
cord-023443-pvz7dll9	731	3	while	while	IN
cord-023443-pvz7dll9	731	4	AE	AE	NNP
cord-023443-pvz7dll9	731	5	markedly	markedly	RB
cord-023443-pvz7dll9	731	6	suppressed	suppress	VBD
cord-023443-pvz7dll9	731	7	NO	no	DT
cord-023443-pvz7dll9	731	8	release	release	NN
cord-023443-pvz7dll9	731	9	from	from	IN
cord-023443-pvz7dll9	731	10	macrophages	macrophage	NNS
cord-023443-pvz7dll9	731	11	alone	alone	RB
cord-023443-pvz7dll9	731	12	,	,	,
cord-023443-pvz7dll9	731	13	it	-PRON-	PRP
cord-023443-pvz7dll9	731	14	significantly	significantly	RB
cord-023443-pvz7dll9	731	15	potentiated	potentiate	VBD
cord-023443-pvz7dll9	731	16	NO	no	DT
cord-023443-pvz7dll9	731	17	production	production	NN
cord-023443-pvz7dll9	731	18	in	in	IN
cord-023443-pvz7dll9	731	19	cocultures	coculture	NNS
cord-023443-pvz7dll9	731	20	of	of	IN
cord-023443-pvz7dll9	731	21	macrophages	macrophage	NNS
cord-023443-pvz7dll9	731	22	and	and	CC
cord-023443-pvz7dll9	731	23	C6	c6	NN
cord-023443-pvz7dll9	731	24	cells	cell	NNS
cord-023443-pvz7dll9	731	25	,	,	,
cord-023443-pvz7dll9	731	26	after	after	IN
cord-023443-pvz7dll9	731	27	48	48	CD
cord-023443-pvz7dll9	731	28	h	h	NN
cord-023443-pvz7dll9	731	29	of	of	IN
cord-023443-pvz7dll9	731	30	cultivation	cultivation	NN
cord-023443-pvz7dll9	731	31	.	.	.
cord-023443-pvz7dll9	732	1	Accordingly	accordingly	RB
cord-023443-pvz7dll9	732	2	,	,	,
cord-023443-pvz7dll9	732	3	the	the	DT
cord-023443-pvz7dll9	732	4	viability	viability	NN
cord-023443-pvz7dll9	732	5	of	of	IN
cord-023443-pvz7dll9	732	6	C6	C6	NNP
cord-023443-pvz7dll9	732	7	cells	cell	NNS
cord-023443-pvz7dll9	732	8	cocultivated	cocultivate	VBN
cord-023443-pvz7dll9	732	9	with	with	IN
cord-023443-pvz7dll9	732	10	macrophages	macrophage	NNS
cord-023443-pvz7dll9	732	11	was	be	VBD
cord-023443-pvz7dll9	732	12	reduced	reduce	VBN
cord-023443-pvz7dll9	732	13	in	in	IN
cord-023443-pvz7dll9	732	14	the	the	DT
cord-023443-pvz7dll9	732	15	presence	presence	NN
cord-023443-pvz7dll9	732	16	of	of	IN
cord-023443-pvz7dll9	732	17	AE	AE	NNP
cord-023443-pvz7dll9	732	18	.	.	.
cord-023443-pvz7dll9	733	1	Moreover	moreover	RB
cord-023443-pvz7dll9	733	2	,	,	,
cord-023443-pvz7dll9	733	3	the	the	DT
cord-023443-pvz7dll9	733	4	observed	observed	JJ
cord-023443-pvz7dll9	733	5	AE	AE	NNP
cord-023443-pvz7dll9	733	6	-	-	HYPH
cord-023443-pvz7dll9	733	7	imposed	impose	VBN
cord-023443-pvz7dll9	733	8	potentiation	potentiation	NN
cord-023443-pvz7dll9	733	9	of	of	IN
cord-023443-pvz7dll9	733	10	NO	no	DT
cord-023443-pvz7dll9	733	11	production	production	NN
cord-023443-pvz7dll9	733	12	in	in	IN
cord-023443-pvz7dll9	733	13	macrophages	macrophage	NNS
cord-023443-pvz7dll9	733	14	was	be	VBD
cord-023443-pvz7dll9	733	15	closely	closely	RB
cord-023443-pvz7dll9	733	16	related	relate	VBN
cord-023443-pvz7dll9	733	17	to	to	IN
cord-023443-pvz7dll9	733	18	macrophage	macrophage	NN
cord-023443-pvz7dll9	733	19	culture	culture	NN
cord-023443-pvz7dll9	733	20	cell	cell	NN
cord-023443-pvz7dll9	733	21	density	density	NN
cord-023443-pvz7dll9	733	22	.	.	.
cord-023443-pvz7dll9	734	1	According	accord	VBG
cord-023443-pvz7dll9	734	2	to	to	IN
cord-023443-pvz7dll9	734	3	these	these	DT
cord-023443-pvz7dll9	734	4	data	datum	NNS
cord-023443-pvz7dll9	734	5	,	,	,
cord-023443-pvz7dll9	734	6	we	-PRON-	PRP
cord-023443-pvz7dll9	734	7	proposed	propose	VBD
cord-023443-pvz7dll9	734	8	that	that	IN
cord-023443-pvz7dll9	734	9	NO	no	DT
cord-023443-pvz7dll9	734	10	modulator	modulator	NN
cord-023443-pvz7dll9	734	11	capacity	capacity	NN
cord-023443-pvz7dll9	734	12	of	of	IN
cord-023443-pvz7dll9	734	13	AE	AE	NNP
cord-023443-pvz7dll9	734	14	strongly	strongly	RB
cord-023443-pvz7dll9	734	15	depended	depend	VBD
cord-023443-pvz7dll9	734	16	on	on	IN
cord-023443-pvz7dll9	734	17	intercellular	intercellular	JJ
cord-023443-pvz7dll9	734	18	contact	contact	NN
cord-023443-pvz7dll9	734	19	,	,	,
cord-023443-pvz7dll9	734	20	indicating	indicate	VBG
cord-023443-pvz7dll9	734	21	that	that	IN
cord-023443-pvz7dll9	734	22	macrophage	macrophage	NN
cord-023443-pvz7dll9	734	23	antitumour	antitumour	JJ
cord-023443-pvz7dll9	734	24	response	response	NN
cord-023443-pvz7dll9	734	25	was	be	VBD
cord-023443-pvz7dll9	734	26	not	not	RB
cord-023443-pvz7dll9	734	27	compromised	compromised	JJ
cord-023443-pvz7dll9	734	28	but	but	CC
cord-023443-pvz7dll9	734	29	even	even	RB
cord-023443-pvz7dll9	734	30	potentiated	potentiate	VBN
cord-023443-pvz7dll9	734	31	by	by	IN
cord-023443-pvz7dll9	734	32	AE	AE	NNP
cord-023443-pvz7dll9	734	33	.	.	.
cord-023443-pvz7dll9	735	1	Immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	735	2	represents	represent	VBZ
cord-023443-pvz7dll9	735	3	an	an	DT
cord-023443-pvz7dll9	735	4	attractive	attractive	JJ
cord-023443-pvz7dll9	735	5	fourth	fourth	JJ
cord-023443-pvz7dll9	735	6	-	-	HYPH
cord-023443-pvz7dll9	735	7	modality	modality	NN
cord-023443-pvz7dll9	735	8	therapeutic	therapeutic	JJ
cord-023443-pvz7dll9	735	9	approach	approach	NN
cord-023443-pvz7dll9	735	10	,	,	,
cord-023443-pvz7dll9	735	11	especially	especially	RB
cord-023443-pvz7dll9	735	12	in	in	IN
cord-023443-pvz7dll9	735	13	the	the	DT
cord-023443-pvz7dll9	735	14	light	light	NN
cord-023443-pvz7dll9	735	15	of	of	IN
cord-023443-pvz7dll9	735	16	the	the	DT
cord-023443-pvz7dll9	735	17	shortcomings	shortcoming	NNS
cord-023443-pvz7dll9	735	18	of	of	IN
cord-023443-pvz7dll9	735	19	conventional	conventional	JJ
cord-023443-pvz7dll9	735	20	surgery	surgery	NN
cord-023443-pvz7dll9	735	21	,	,	,
cord-023443-pvz7dll9	735	22	radiation	radiation	NN
cord-023443-pvz7dll9	735	23	and	and	CC
cord-023443-pvz7dll9	735	24	chemotherapies	chemotherapy	NNS
cord-023443-pvz7dll9	735	25	in	in	IN
cord-023443-pvz7dll9	735	26	the	the	DT
cord-023443-pvz7dll9	735	27	management	management	NN
cord-023443-pvz7dll9	735	28	of	of	IN
cord-023443-pvz7dll9	735	29	metastatic	metastatic	JJ
cord-023443-pvz7dll9	735	30	cancer	cancer	NN
cord-023443-pvz7dll9	735	31	.	.	.
cord-023443-pvz7dll9	736	1	To	to	IN
cord-023443-pvz7dll9	736	2	this	this	DT
cord-023443-pvz7dll9	736	3	end	end	NN
cord-023443-pvz7dll9	736	4	,	,	,
cord-023443-pvz7dll9	736	5	a	a	DT
cord-023443-pvz7dll9	736	6	large	large	JJ
cord-023443-pvz7dll9	736	7	number	number	NN
cord-023443-pvz7dll9	736	8	of	of	IN
cord-023443-pvz7dll9	736	9	peptide	peptide	JJ
cord-023443-pvz7dll9	736	10	antigens	antigen	NNS
cord-023443-pvz7dll9	736	11	derived	derive	VBN
cord-023443-pvz7dll9	736	12	from	from	IN
cord-023443-pvz7dll9	736	13	TAA	TAA	NNP
cord-023443-pvz7dll9	736	14	have	have	VBP
cord-023443-pvz7dll9	736	15	been	be	VBN
cord-023443-pvz7dll9	736	16	applied	apply	VBN
cord-023443-pvz7dll9	736	17	in	in	IN
cord-023443-pvz7dll9	736	18	immunotherapeutic	immunotherapeutic	JJ
cord-023443-pvz7dll9	736	19	trials	trial	NNS
cord-023443-pvz7dll9	736	20	for	for	IN
cord-023443-pvz7dll9	736	21	the	the	DT
cord-023443-pvz7dll9	736	22	treatment	treatment	NN
cord-023443-pvz7dll9	736	23	of	of	IN
cord-023443-pvz7dll9	736	24	various	various	JJ
cord-023443-pvz7dll9	736	25	malignancies	malignancy	NNS
cord-023443-pvz7dll9	736	26	,	,	,
cord-023443-pvz7dll9	736	27	e.g.	e.g.	IN
cord-023443-pvz7dll9	736	28	cancers	cancer	NNS
cord-023443-pvz7dll9	736	29	of	of	IN
cord-023443-pvz7dll9	736	30	the	the	DT
cord-023443-pvz7dll9	736	31	breast	breast	NN
cord-023443-pvz7dll9	736	32	,	,	,
cord-023443-pvz7dll9	736	33	prostate	prostate	NN
cord-023443-pvz7dll9	736	34	and	and	CC
cord-023443-pvz7dll9	736	35	kidney	kidney	NN
cord-023443-pvz7dll9	736	36	,	,	,
cord-023443-pvz7dll9	736	37	in	in	IN
cord-023443-pvz7dll9	736	38	addition	addition	NN
cord-023443-pvz7dll9	736	39	to	to	IN
cord-023443-pvz7dll9	736	40	haematological	haematological	JJ
cord-023443-pvz7dll9	736	41	cancers	cancer	NNS
cord-023443-pvz7dll9	736	42	.	.	.
cord-023443-pvz7dll9	737	1	In	in	IN
cord-023443-pvz7dll9	737	2	some	some	DT
cord-023443-pvz7dll9	737	3	cases	case	NNS
cord-023443-pvz7dll9	737	4	the	the	DT
cord-023443-pvz7dll9	737	5	response	response	NN
cord-023443-pvz7dll9	737	6	rates	rate	NNS
cord-023443-pvz7dll9	737	7	have	have	VBP
cord-023443-pvz7dll9	737	8	been	be	VBN
cord-023443-pvz7dll9	737	9	impressive	impressive	JJ
cord-023443-pvz7dll9	737	10	and	and	CC
cord-023443-pvz7dll9	737	11	no	no	DT
cord-023443-pvz7dll9	737	12	adverse	adverse	JJ
cord-023443-pvz7dll9	737	13	autoimmunity	autoimmunity	NN
cord-023443-pvz7dll9	737	14	have	have	VBP
cord-023443-pvz7dll9	737	15	been	be	VBN
cord-023443-pvz7dll9	737	16	observed	observe	VBN
cord-023443-pvz7dll9	737	17	.	.	.
cord-023443-pvz7dll9	738	1	A	a	DT
cord-023443-pvz7dll9	738	2	major	major	JJ
cord-023443-pvz7dll9	738	3	strategic	strategic	JJ
cord-023443-pvz7dll9	738	4	difficulty	difficulty	NN
cord-023443-pvz7dll9	738	5	associated	associate	VBN
cord-023443-pvz7dll9	738	6	with	with	IN
cord-023443-pvz7dll9	738	7	these	these	DT
cord-023443-pvz7dll9	738	8	trials	trial	NNS
cord-023443-pvz7dll9	738	9	relates	relate	VBZ
cord-023443-pvz7dll9	738	10	to	to	IN
cord-023443-pvz7dll9	738	11	the	the	DT
cord-023443-pvz7dll9	738	12	choice	choice	NN
cord-023443-pvz7dll9	738	13	of	of	IN
cord-023443-pvz7dll9	738	14	best	best	RB
cord-023443-pvz7dll9	738	15	-	-	HYPH
cord-023443-pvz7dll9	738	16	suited	suit	VBN
cord-023443-pvz7dll9	738	17	peptide	peptide	NN
cord-023443-pvz7dll9	738	18	antigens	antigen	NNS
cord-023443-pvz7dll9	738	19	.	.	.
cord-023443-pvz7dll9	739	1	The	the	DT
cord-023443-pvz7dll9	739	2	vast	vast	JJ
cord-023443-pvz7dll9	739	3	majority	majority	NN
cord-023443-pvz7dll9	739	4	of	of	IN
cord-023443-pvz7dll9	739	5	the	the	DT
cord-023443-pvz7dll9	739	6	antigens	antigen	NNS
cord-023443-pvz7dll9	739	7	described	describe	VBN
cord-023443-pvz7dll9	739	8	thus	thus	RB
cord-023443-pvz7dll9	739	9	far	far	RB
cord-023443-pvz7dll9	739	10	is	be	VBZ
cord-023443-pvz7dll9	739	11	not	not	RB
cord-023443-pvz7dll9	739	12	vital	vital	JJ
cord-023443-pvz7dll9	739	13	for	for	IN
cord-023443-pvz7dll9	739	14	survival	survival	NN
cord-023443-pvz7dll9	739	15	and	and	CC
cord-023443-pvz7dll9	739	16	growth	growth	NN
cord-023443-pvz7dll9	739	17	of	of	IN
cord-023443-pvz7dll9	739	18	the	the	DT
cord-023443-pvz7dll9	739	19	tumour	tumour	NN
cord-023443-pvz7dll9	739	20	cells	cell	NNS
cord-023443-pvz7dll9	739	21	,	,	,
cord-023443-pvz7dll9	739	22	and	and	CC
cord-023443-pvz7dll9	739	23	immunoselection	immunoselection	NN
cord-023443-pvz7dll9	739	24	of	of	IN
cord-023443-pvz7dll9	739	25	antigen	antigen	NN
cord-023443-pvz7dll9	739	26	-	-	HYPH
cord-023443-pvz7dll9	739	27	loss	loss	NN
cord-023443-pvz7dll9	739	28	variants	variant	NNS
cord-023443-pvz7dll9	739	29	may	may	MD
cord-023443-pvz7dll9	739	30	therefore	therefore	RB
cord-023443-pvz7dll9	739	31	prove	prove	VB
cord-023443-pvz7dll9	739	32	to	to	TO
cord-023443-pvz7dll9	739	33	be	be	VB
cord-023443-pvz7dll9	739	34	an	an	DT
cord-023443-pvz7dll9	739	35	additional	additional	JJ
cord-023443-pvz7dll9	739	36	obstacle	obstacle	NN
cord-023443-pvz7dll9	739	37	for	for	IN
cord-023443-pvz7dll9	739	38	the	the	DT
cord-023443-pvz7dll9	739	39	clinical	clinical	JJ
cord-023443-pvz7dll9	739	40	applicability	applicability	NN
cord-023443-pvz7dll9	739	41	of	of	IN
cord-023443-pvz7dll9	739	42	most	most	JJS
cord-023443-pvz7dll9	739	43	of	of	IN
cord-023443-pvz7dll9	739	44	the	the	DT
cord-023443-pvz7dll9	739	45	known	know	VBN
cord-023443-pvz7dll9	739	46	peptide	peptide	NN
cord-023443-pvz7dll9	739	47	epitopes	epitope	NNS
cord-023443-pvz7dll9	739	48	.	.	.
cord-023443-pvz7dll9	740	1	In	in	IN
cord-023443-pvz7dll9	740	2	this	this	DT
cord-023443-pvz7dll9	740	3	respect	respect	NN
cord-023443-pvz7dll9	740	4	,	,	,
cord-023443-pvz7dll9	740	5	the	the	DT
cord-023443-pvz7dll9	740	6	development	development	NN
cord-023443-pvz7dll9	740	7	of	of	IN
cord-023443-pvz7dll9	740	8	acquired	acquire	VBN
cord-023443-pvz7dll9	740	9	antigen	antigen	NN
cord-023443-pvz7dll9	740	10	loss	loss	NN
cord-023443-pvz7dll9	740	11	during	during	IN
cord-023443-pvz7dll9	740	12	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	740	13	has	have	VBZ
cord-023443-pvz7dll9	740	14	been	be	VBN
cord-023443-pvz7dll9	740	15	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	740	16	in	in	IN
cord-023443-pvz7dll9	740	17	several	several	JJ
cord-023443-pvz7dll9	740	18	cases	case	NNS
cord-023443-pvz7dll9	740	19	.	.	.
cord-023443-pvz7dll9	741	1	Obviously	obviously	RB
cord-023443-pvz7dll9	741	2	,	,	,
cord-023443-pvz7dll9	741	3	the	the	DT
cord-023443-pvz7dll9	741	4	development	development	NN
cord-023443-pvz7dll9	741	5	of	of	IN
cord-023443-pvz7dll9	741	6	loss	loss	NN
cord-023443-pvz7dll9	741	7	-	-	HYPH
cord-023443-pvz7dll9	741	8	variant	variant	NN
cord-023443-pvz7dll9	741	9	tumour	tumour	NN
cord-023443-pvz7dll9	741	10	cells	cell	NNS
cord-023443-pvz7dll9	741	11	implies	imply	VBZ
cord-023443-pvz7dll9	741	12	that	that	IN
cord-023443-pvz7dll9	741	13	these	these	DT
cord-023443-pvz7dll9	741	14	cells	cell	NNS
cord-023443-pvz7dll9	741	15	acquire	acquire	VBP
cord-023443-pvz7dll9	741	16	a	a	DT
cord-023443-pvz7dll9	741	17	pronounced	pronounce	VBN
cord-023443-pvz7dll9	741	18	growth	growth	NN
cord-023443-pvz7dll9	741	19	advantage	advantage	NN
cord-023443-pvz7dll9	741	20	and	and	CC
cord-023443-pvz7dll9	741	21	are	be	VBP
cord-023443-pvz7dll9	741	22	left	leave	VBN
cord-023443-pvz7dll9	741	23	unaffected	unaffected	JJ
cord-023443-pvz7dll9	741	24	by	by	IN
cord-023443-pvz7dll9	741	25	further	further	JJ
cord-023443-pvz7dll9	741	26	treatment	treatment	NN
cord-023443-pvz7dll9	741	27	.	.	.
cord-023443-pvz7dll9	742	1	Ideally	ideally	RB
cord-023443-pvz7dll9	742	2	,	,	,
cord-023443-pvz7dll9	742	3	target	target	NN
cord-023443-pvz7dll9	742	4	antigens	antigen	NNS
cord-023443-pvz7dll9	742	5	should	should	MD
cord-023443-pvz7dll9	742	6	be	be	VB
cord-023443-pvz7dll9	742	7	derived	derive	VBN
cord-023443-pvz7dll9	742	8	from	from	IN
cord-023443-pvz7dll9	742	9	proteins	protein	NNS
cord-023443-pvz7dll9	742	10	required	require	VBN
cord-023443-pvz7dll9	742	11	for	for	IN
cord-023443-pvz7dll9	742	12	survival	survival	NN
cord-023443-pvz7dll9	742	13	and	and	CC
cord-023443-pvz7dll9	742	14	growth	growth	NN
cord-023443-pvz7dll9	742	15	of	of	IN
cord-023443-pvz7dll9	742	16	tumour	tumour	NN
cord-023443-pvz7dll9	742	17	cells	cell	NNS
cord-023443-pvz7dll9	742	18	,	,	,
cord-023443-pvz7dll9	742	19	as	as	IN
cord-023443-pvz7dll9	742	20	antigens	antigen	NNS
cord-023443-pvz7dll9	742	21	with	with	IN
cord-023443-pvz7dll9	742	22	these	these	DT
cord-023443-pvz7dll9	742	23	characteristics	characteristic	NNS
cord-023443-pvz7dll9	742	24	would	would	MD
cord-023443-pvz7dll9	742	25	not	not	RB
cord-023443-pvz7dll9	742	26	be	be	VB
cord-023443-pvz7dll9	742	27	inflicted	inflict	VBN
cord-023443-pvz7dll9	742	28	by	by	IN
cord-023443-pvz7dll9	742	29	the	the	DT
cord-023443-pvz7dll9	742	30	development	development	NN
cord-023443-pvz7dll9	742	31	of	of	IN
cord-023443-pvz7dll9	742	32	loss	loss	NN
cord-023443-pvz7dll9	742	33	-	-	HYPH
cord-023443-pvz7dll9	742	34	variant	variant	NN
cord-023443-pvz7dll9	742	35	tumour	tumour	NN
cord-023443-pvz7dll9	742	36	cells	cell	NNS
cord-023443-pvz7dll9	742	37	.	.	.
cord-023443-pvz7dll9	743	1	In	in	IN
cord-023443-pvz7dll9	743	2	this	this	DT
cord-023443-pvz7dll9	743	3	respect	respect	NN
cord-023443-pvz7dll9	743	4	,	,	,
cord-023443-pvz7dll9	743	5	several	several	JJ
cord-023443-pvz7dll9	743	6	inhibitors	inhibitor	NNS
cord-023443-pvz7dll9	743	7	of	of	IN
cord-023443-pvz7dll9	743	8	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	743	9	proteins	protein	NNS
cord-023443-pvz7dll9	743	10	(	(	-LRB-
cord-023443-pvz7dll9	743	11	IAPs	IAPs	NNP
cord-023443-pvz7dll9	743	12	)	)	-RRB-
cord-023443-pvz7dll9	743	13	are	be	VBP
cord-023443-pvz7dll9	743	14	universally	universally	RB
cord-023443-pvz7dll9	743	15	expressed	express	VBN
cord-023443-pvz7dll9	743	16	among	among	IN
cord-023443-pvz7dll9	743	17	tumours	tumour	NNS
cord-023443-pvz7dll9	743	18	and	and	CC
cord-023443-pvz7dll9	743	19	play	play	VB
cord-023443-pvz7dll9	743	20	an	an	DT
cord-023443-pvz7dll9	743	21	important	important	JJ
cord-023443-pvz7dll9	743	22	role	role	NN
cord-023443-pvz7dll9	743	23	in	in	IN
cord-023443-pvz7dll9	743	24	tumour	tumour	NN
cord-023443-pvz7dll9	743	25	cell	cell	NN
cord-023443-pvz7dll9	743	26	escape	escape	NN
cord-023443-pvz7dll9	743	27	from	from	IN
cord-023443-pvz7dll9	743	28	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	743	29	.	.	.
cord-023443-pvz7dll9	744	1	We	-PRON-	PRP
cord-023443-pvz7dll9	744	2	have	have	VBP
cord-023443-pvz7dll9	744	3	characterized	characterize	VBN
cord-023443-pvz7dll9	744	4	spontaneous	spontaneous	JJ
cord-023443-pvz7dll9	744	5	T	t	NN
cord-023443-pvz7dll9	744	6	-	-	HYPH
cord-023443-pvz7dll9	744	7	cell	cell	NN
cord-023443-pvz7dll9	744	8	reactivity	reactivity	NN
cord-023443-pvz7dll9	744	9	against	against	IN
cord-023443-pvz7dll9	744	10	IAPderived	iapderived	JJ
cord-023443-pvz7dll9	744	11	peptides	peptide	NNS
cord-023443-pvz7dll9	744	12	in	in	IN
cord-023443-pvz7dll9	744	13	cancer	cancer	NN
cord-023443-pvz7dll9	744	14	patients	patient	NNS
cord-023443-pvz7dll9	744	15	.	.	.
cord-023443-pvz7dll9	745	1	From	from	IN
cord-023443-pvz7dll9	745	2	the	the	DT
cord-023443-pvz7dll9	745	3	IAP	IAP	NNP
cord-023443-pvz7dll9	745	4	survivin	survivin	NN
cord-023443-pvz7dll9	745	5	,	,	,
cord-023443-pvz7dll9	745	6	we	-PRON-	PRP
cord-023443-pvz7dll9	745	7	have	have	VBP
cord-023443-pvz7dll9	745	8	characterized	characterize	VBN
cord-023443-pvz7dll9	745	9	peptides	peptide	NNS
cord-023443-pvz7dll9	745	10	restricted	restrict	VBN
cord-023443-pvz7dll9	745	11	to	to	IN
cord-023443-pvz7dll9	745	12	the	the	DT
cord-023443-pvz7dll9	745	13	Class	class	NN
cord-023443-pvz7dll9	746	1	I	-PRON-	PRP
cord-023443-pvz7dll9	746	2	molecules	molecule	VBZ
cord-023443-pvz7dll9	746	3	HLA	HLA	NNP
cord-023443-pvz7dll9	746	4	-	-	HYPH
cord-023443-pvz7dll9	746	5	A1	A1	NNP
cord-023443-pvz7dll9	746	6	,	,	,
cord-023443-pvz7dll9	746	7	A2	A2	NNP
cord-023443-pvz7dll9	746	8	,	,	,
cord-023443-pvz7dll9	746	9	A3	A3	NNP
cord-023443-pvz7dll9	746	10	,	,	,
cord-023443-pvz7dll9	746	11	A11	A11	NNP
cord-023443-pvz7dll9	746	12	,	,	,
cord-023443-pvz7dll9	746	13	B7	b7	NN
cord-023443-pvz7dll9	746	14	and	and	CC
cord-023443-pvz7dll9	746	15	B35	B35	NNP
cord-023443-pvz7dll9	746	16	.	.	.
cord-023443-pvz7dll9	747	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	747	2	,	,	,
cord-023443-pvz7dll9	747	3	we	-PRON-	PRP
cord-023443-pvz7dll9	747	4	have	have	VBP
cord-023443-pvz7dll9	747	5	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	747	6	that	that	IN
cord-023443-pvz7dll9	747	7	survivin	survivin	NN
cord-023443-pvz7dll9	747	8	-	-	HYPH
cord-023443-pvz7dll9	747	9	specific	specific	JJ
cord-023443-pvz7dll9	747	10	T	t	NN
cord-023443-pvz7dll9	747	11	cells	cell	NNS
cord-023443-pvz7dll9	747	12	infiltrate	infiltrate	VBP
cord-023443-pvz7dll9	747	13	metastatic	metastatic	JJ
cord-023443-pvz7dll9	747	14	lesions	lesion	NNS
cord-023443-pvz7dll9	747	15	and	and	CC
cord-023443-pvz7dll9	747	16	that	that	IN
cord-023443-pvz7dll9	747	17	isolated	isolate	VBN
cord-023443-pvz7dll9	747	18	survivinspecific	survivinspecific	NN
cord-023443-pvz7dll9	747	19	CTLs	ctl	NNS
cord-023443-pvz7dll9	747	20	are	be	VBP
cord-023443-pvz7dll9	747	21	capable	capable	JJ
cord-023443-pvz7dll9	747	22	of	of	IN
cord-023443-pvz7dll9	747	23	killing	kill	VBG
cord-023443-pvz7dll9	747	24	HLA	HLA	NNP
cord-023443-pvz7dll9	747	25	-	-	HYPH
cord-023443-pvz7dll9	747	26	matched	match	VBN
cord-023443-pvz7dll9	747	27	tumour	tumour	NN
cord-023443-pvz7dll9	747	28	cells	cell	NNS
cord-023443-pvz7dll9	747	29	.	.	.
cord-023443-pvz7dll9	748	1	Survivin	Survivin	NNP
cord-023443-pvz7dll9	748	2	-	-	HYPH
cord-023443-pvz7dll9	748	3	derived	derive	VBN
cord-023443-pvz7dll9	748	4	peptides	peptide	NNS
cord-023443-pvz7dll9	748	5	are	be	VBP
cord-023443-pvz7dll9	748	6	now	now	RB
cord-023443-pvz7dll9	748	7	in	in	IN
cord-023443-pvz7dll9	748	8	clinical	clinical	JJ
cord-023443-pvz7dll9	748	9	trial	trial	NN
cord-023443-pvz7dll9	748	10	,	,	,
cord-023443-pvz7dll9	748	11	and	and	CC
cord-023443-pvz7dll9	748	12	continued	continue	VBD
cord-023443-pvz7dll9	748	13	work	work	NN
cord-023443-pvz7dll9	748	14	in	in	IN
cord-023443-pvz7dll9	748	15	our	-PRON-	PRP$
cord-023443-pvz7dll9	748	16	lab	lab	NN
cord-023443-pvz7dll9	748	17	has	have	VBZ
cord-023443-pvz7dll9	748	18	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	748	19	that	that	IN
cord-023443-pvz7dll9	748	20	other	other	JJ
cord-023443-pvz7dll9	748	21	IAPs	iap	NNS
cord-023443-pvz7dll9	748	22	are	be	VBP
cord-023443-pvz7dll9	748	23	targets	target	NNS
cord-023443-pvz7dll9	748	24	for	for	IN
cord-023443-pvz7dll9	748	25	spontaneous	spontaneous	JJ
cord-023443-pvz7dll9	748	26	T	t	NN
cord-023443-pvz7dll9	748	27	-	-	HYPH
cord-023443-pvz7dll9	748	28	cell	cell	NN
cord-023443-pvz7dll9	748	29	reactivity	reactivity	NN
cord-023443-pvz7dll9	748	30	in	in	IN
cord-023443-pvz7dll9	748	31	cancer	cancer	NN
cord-023443-pvz7dll9	748	32	patients	patient	NNS
cord-023443-pvz7dll9	748	33	.	.	.
cord-023443-pvz7dll9	749	1	We	-PRON-	PRP
cord-023443-pvz7dll9	749	2	previously	previously	RB
cord-023443-pvz7dll9	749	3	reported	report	VBD
cord-023443-pvz7dll9	749	4	that	that	IN
cord-023443-pvz7dll9	749	5	in	in	IN
cord-023443-pvz7dll9	749	6	mice	mouse	NNS
cord-023443-pvz7dll9	749	7	with	with	IN
cord-023443-pvz7dll9	749	8	large	large	JJ
cord-023443-pvz7dll9	749	9	progressing	progress	VBG
cord-023443-pvz7dll9	749	10	T	t	NN
cord-023443-pvz7dll9	749	11	-	-	HYPH
cord-023443-pvz7dll9	749	12	cell	cell	NN
cord-023443-pvz7dll9	749	13	lymphoma	lymphoma	NN
cord-023443-pvz7dll9	749	14	tumours	tumour	NNS
cord-023443-pvz7dll9	749	15	,	,	,
cord-023443-pvz7dll9	749	16	dysfunctions	dysfunction	NNS
cord-023443-pvz7dll9	749	17	in	in	IN
cord-023443-pvz7dll9	749	18	the	the	DT
cord-023443-pvz7dll9	749	19	antitumour	antitumour	JJ
cord-023443-pvz7dll9	749	20	CTL	CTL	NNP
cord-023443-pvz7dll9	749	21	activity	activity	NN
cord-023443-pvz7dll9	749	22	occur	occur	VBP
cord-023443-pvz7dll9	749	23	,	,	,
cord-023443-pvz7dll9	749	24	associated	associate	VBN
cord-023443-pvz7dll9	749	25	with	with	IN
cord-023443-pvz7dll9	749	26	an	an	DT
cord-023443-pvz7dll9	749	27	accumulation	accumulation	NN
cord-023443-pvz7dll9	749	28	of	of	IN
cord-023443-pvz7dll9	749	29	splenic	splenic	JJ
cord-023443-pvz7dll9	749	30	arginase	arginase	NN
cord-023443-pvz7dll9	749	31	-	-	HYPH
cord-023443-pvz7dll9	749	32	producing	produce	VBG
cord-023443-pvz7dll9	749	33	myeloid	myeloid	NN
cord-023443-pvz7dll9	749	34	suppressor	suppressor	NN
cord-023443-pvz7dll9	749	35	cells	cell	NNS
cord-023443-pvz7dll9	749	36	(	(	-LRB-
cord-023443-pvz7dll9	749	37	MSCs	msc	NNS
cord-023443-pvz7dll9	749	38	)	)	-RRB-
cord-023443-pvz7dll9	749	39	.	.	.
cord-023443-pvz7dll9	750	1	In	in	IN
cord-023443-pvz7dll9	750	2	this	this	DT
cord-023443-pvz7dll9	750	3	study	study	NN
cord-023443-pvz7dll9	750	4	,	,	,
cord-023443-pvz7dll9	750	5	we	-PRON-	PRP
cord-023443-pvz7dll9	750	6	first	first	RB
cord-023443-pvz7dll9	750	7	demonstrate	demonstrate	VBP
cord-023443-pvz7dll9	750	8	that	that	IN
cord-023443-pvz7dll9	750	9	both	both	CC
cord-023443-pvz7dll9	750	10	the	the	DT
cord-023443-pvz7dll9	750	11	presence	presence	NN
cord-023443-pvz7dll9	750	12	and	and	CC
cord-023443-pvz7dll9	750	13	the	the	DT
cord-023443-pvz7dll9	750	14	activation	activation	NN
cord-023443-pvz7dll9	750	15	state	state	NN
cord-023443-pvz7dll9	750	16	of	of	IN
cord-023443-pvz7dll9	750	17	these	these	DT
cord-023443-pvz7dll9	750	18	MSC	MSC	NNP
cord-023443-pvz7dll9	750	19	depends	depend	VBZ
cord-023443-pvz7dll9	750	20	on	on	IN
cord-023443-pvz7dll9	750	21	tumour	tumour	NN
cord-023443-pvz7dll9	750	22	evolution	evolution	NN
cord-023443-pvz7dll9	750	23	.	.	.
cord-023443-pvz7dll9	751	1	While	while	IN
cord-023443-pvz7dll9	751	2	in	in	IN
cord-023443-pvz7dll9	751	3	tumour	tumour	NN
cord-023443-pvz7dll9	751	4	regressors	regressor	NNS
cord-023443-pvz7dll9	751	5	hardly	hardly	RB
cord-023443-pvz7dll9	751	6	any	any	DT
cord-023443-pvz7dll9	751	7	arginase	arginase	NN
cord-023443-pvz7dll9	751	8	-	-	HYPH
cord-023443-pvz7dll9	751	9	producing	produce	VBG
cord-023443-pvz7dll9	751	10	MSC	MSC	NNP
cord-023443-pvz7dll9	751	11	can	can	MD
cord-023443-pvz7dll9	751	12	be	be	VB
cord-023443-pvz7dll9	751	13	found	find	VBN
cord-023443-pvz7dll9	751	14	,	,	,
cord-023443-pvz7dll9	751	15	both	both	CC
cord-023443-pvz7dll9	751	16	the	the	DT
cord-023443-pvz7dll9	751	17	amount	amount	NN
cord-023443-pvz7dll9	751	18	and	and	CC
cord-023443-pvz7dll9	751	19	the	the	DT
cord-023443-pvz7dll9	751	20	arginase	arginase	NN
cord-023443-pvz7dll9	751	21	activity	activity	NN
cord-023443-pvz7dll9	751	22	of	of	IN
cord-023443-pvz7dll9	751	23	this	this	DT
cord-023443-pvz7dll9	751	24	population	population	NN
cord-023443-pvz7dll9	751	25	expands	expand	VBZ
cord-023443-pvz7dll9	751	26	from	from	IN
cord-023443-pvz7dll9	751	27	early	early	RB
cord-023443-pvz7dll9	751	28	over	over	IN
cord-023443-pvz7dll9	751	29	late	late	JJ
cord-023443-pvz7dll9	751	30	progressors	progressor	NNS
cord-023443-pvz7dll9	751	31	.	.	.
cord-023443-pvz7dll9	752	1	This	this	DT
cord-023443-pvz7dll9	752	2	gradual	gradual	JJ
cord-023443-pvz7dll9	752	3	induction	induction	NN
cord-023443-pvz7dll9	752	4	of	of	IN
cord-023443-pvz7dll9	752	5	MSCs	mscs	NN
cord-023443-pvz7dll9	752	6	is	be	VBZ
cord-023443-pvz7dll9	752	7	paralleled	parallel	VBN
cord-023443-pvz7dll9	752	8	by	by	IN
cord-023443-pvz7dll9	752	9	an	an	DT
cord-023443-pvz7dll9	752	10	increasing	increase	VBG
cord-023443-pvz7dll9	752	11	suppression	suppression	NN
cord-023443-pvz7dll9	752	12	of	of	IN
cord-023443-pvz7dll9	752	13	CTL	CTL	NNP
cord-023443-pvz7dll9	752	14	activity	activity	NN
cord-023443-pvz7dll9	752	15	and	and	CC
cord-023443-pvz7dll9	752	16	Th1	th1	NN
cord-023443-pvz7dll9	752	17	,	,	,
cord-023443-pvz7dll9	752	18	but	but	CC
cord-023443-pvz7dll9	752	19	not	not	RB
cord-023443-pvz7dll9	752	20	Th2	th2	CD
cord-023443-pvz7dll9	752	21	,	,	,
cord-023443-pvz7dll9	752	22	cytokine	cytokine	JJ
cord-023443-pvz7dll9	752	23	production	production	NN
cord-023443-pvz7dll9	752	24	.	.	.
cord-023443-pvz7dll9	753	1	Upon	upon	IN
cord-023443-pvz7dll9	753	2	analysing	analyse	VBG
cord-023443-pvz7dll9	753	3	the	the	DT
cord-023443-pvz7dll9	753	4	molecular	molecular	JJ
cord-023443-pvz7dll9	753	5	repertoire	repertoire	NN
cord-023443-pvz7dll9	753	6	of	of	IN
cord-023443-pvz7dll9	753	7	MSC	MSC	NNP
cord-023443-pvz7dll9	753	8	in	in	IN
cord-023443-pvz7dll9	753	9	vitro	vitro	FW
cord-023443-pvz7dll9	753	10	,	,	,
cord-023443-pvz7dll9	753	11	we	-PRON-	PRP
cord-023443-pvz7dll9	753	12	found	find	VBD
cord-023443-pvz7dll9	753	13	,	,	,
cord-023443-pvz7dll9	753	14	besides	besides	IN
cord-023443-pvz7dll9	753	15	arginase1	arginase1	NN
cord-023443-pvz7dll9	753	16	,	,	,
cord-023443-pvz7dll9	753	17	a	a	DT
cord-023443-pvz7dll9	753	18	well	well	RB
cord-023443-pvz7dll9	753	19	-	-	HYPH
cord-023443-pvz7dll9	753	20	established	establish	VBN
cord-023443-pvz7dll9	753	21	marker	marker	NN
cord-023443-pvz7dll9	753	22	for	for	IN
cord-023443-pvz7dll9	753	23	alternatively	alternatively	RB
cord-023443-pvz7dll9	753	24	activated	activate	VBN
cord-023443-pvz7dll9	753	25	myeloid	myeloid	NN
cord-023443-pvz7dll9	753	26	cells	cell	NNS
cord-023443-pvz7dll9	753	27	or	or	CC
cord-023443-pvz7dll9	753	28	M2	M2	NNP
cord-023443-pvz7dll9	753	29	,	,	,
cord-023443-pvz7dll9	753	30	a	a	DT
cord-023443-pvz7dll9	753	31	strong	strong	JJ
cord-023443-pvz7dll9	753	32	upregulation	upregulation	NN
cord-023443-pvz7dll9	753	33	of	of	IN
cord-023443-pvz7dll9	753	34	FIZZ1	FIZZ1	NNP
cord-023443-pvz7dll9	753	35	and	and	CC
cord-023443-pvz7dll9	753	36	Ym	Ym	NNP
cord-023443-pvz7dll9	753	37	,	,	,
cord-023443-pvz7dll9	753	38	two	two	CD
cord-023443-pvz7dll9	753	39	additional	additional	JJ
cord-023443-pvz7dll9	753	40	recently	recently	RB
cord-023443-pvz7dll9	753	41	identified	identify	VBN
cord-023443-pvz7dll9	753	42	markers	marker	NNS
cord-023443-pvz7dll9	753	43	for	for	IN
cord-023443-pvz7dll9	753	44	M2	M2	NNP
cord-023443-pvz7dll9	753	45	.	.	.
cord-023443-pvz7dll9	754	1	Further	further	JJ
cord-023443-pvz7dll9	754	2	evaluation	evaluation	NN
cord-023443-pvz7dll9	754	3	of	of	IN
cord-023443-pvz7dll9	754	4	molecular	molecular	JJ
cord-023443-pvz7dll9	754	5	markers	marker	NNS
cord-023443-pvz7dll9	754	6	by	by	IN
cord-023443-pvz7dll9	754	7	microarray	microarray	NN
cord-023443-pvz7dll9	754	8	analysis	analysis	NN
cord-023443-pvz7dll9	754	9	in	in	IN
cord-023443-pvz7dll9	754	10	MSC	MSC	NNP
cord-023443-pvz7dll9	754	11	yielded	yield	VBD
cord-023443-pvz7dll9	754	12	genes	gene	NNS
cord-023443-pvz7dll9	754	13	involved	involve	VBN
cord-023443-pvz7dll9	754	14	in	in	IN
cord-023443-pvz7dll9	754	15	wound	wound	JJ
cord-023443-pvz7dll9	754	16	healing	healing	NN
cord-023443-pvz7dll9	754	17	(	(	-LRB-
cord-023443-pvz7dll9	754	18	e.g.	e.g.	JJ
cord-023443-pvz7dll9	754	19	coagulation	coagulation	NN
cord-023443-pvz7dll9	754	20	factor	factor	NN
cord-023443-pvz7dll9	754	21	XIIIa	XIIIa	NNPS
cord-023443-pvz7dll9	754	22	)	)	-RRB-
cord-023443-pvz7dll9	754	23	,	,	,
cord-023443-pvz7dll9	754	24	anti	anti	JJ
cord-023443-pvz7dll9	754	25	-	-	JJ
cord-023443-pvz7dll9	754	26	inflammation	inflammation	NN
cord-023443-pvz7dll9	754	27	(	(	-LRB-
cord-023443-pvz7dll9	754	28	e.g.	e.g.	RB
cord-023443-pvz7dll9	754	29	selenoprotein	selenoprotein	NNP
cord-023443-pvz7dll9	754	30	P	P	NNP
cord-023443-pvz7dll9	754	31	)	)	-RRB-
cord-023443-pvz7dll9	754	32	,	,	,
cord-023443-pvz7dll9	754	33	immunomodulation	immunomodulation	NNP
cord-023443-pvz7dll9	754	34	(	(	-LRB-
cord-023443-pvz7dll9	754	35	e.g.	e.g.	RB
cord-023443-pvz7dll9	754	36	PD	PD	NNP
cord-023443-pvz7dll9	754	37	-	-	HYPH
cord-023443-pvz7dll9	754	38	L2	L2	NNP
cord-023443-pvz7dll9	754	39	)	)	-RRB-
cord-023443-pvz7dll9	754	40	and	and	CC
cord-023443-pvz7dll9	754	41	fat	fat	NN
cord-023443-pvz7dll9	754	42	and	and	CC
cord-023443-pvz7dll9	754	43	sugar	sugar	NN
cord-023443-pvz7dll9	754	44	metabolism	metabolism	NN
cord-023443-pvz7dll9	754	45	(	(	-LRB-
cord-023443-pvz7dll9	754	46	e.g.	e.g.	IN
cord-023443-pvz7dll9	754	47	leptin	leptin	NN
cord-023443-pvz7dll9	754	48	receptor	receptor	NN
cord-023443-pvz7dll9	754	49	)	)	-RRB-
cord-023443-pvz7dll9	754	50	.	.	.
cord-023443-pvz7dll9	755	1	Of	of	IN
cord-023443-pvz7dll9	755	2	note	note	NN
cord-023443-pvz7dll9	755	3	,	,	,
cord-023443-pvz7dll9	755	4	many	many	JJ
cord-023443-pvz7dll9	755	5	of	of	IN
cord-023443-pvz7dll9	755	6	these	these	DT
cord-023443-pvz7dll9	755	7	genes	gene	NNS
cord-023443-pvz7dll9	755	8	are	be	VBP
cord-023443-pvz7dll9	755	9	regulated	regulate	VBN
cord-023443-pvz7dll9	755	10	by	by	IN
cord-023443-pvz7dll9	755	11	type	type	NN
cord-023443-pvz7dll9	755	12	2	2	CD
cord-023443-pvz7dll9	755	13	cytokines	cytokine	NNS
cord-023443-pvz7dll9	755	14	(	(	-LRB-
cord-023443-pvz7dll9	755	15	IL-4	IL-4	NNP
cord-023443-pvz7dll9	755	16	,	,	,
cord-023443-pvz7dll9	755	17	IL-13	IL-13	NNP
cord-023443-pvz7dll9	755	18	and	and	CC
cord-023443-pvz7dll9	755	19	IL-10	IL-10	NNP
cord-023443-pvz7dll9	755	20	)	)	-RRB-
cord-023443-pvz7dll9	755	21	and	and	CC
cord-023443-pvz7dll9	755	22	are	be	VBP
cord-023443-pvz7dll9	755	23	therefore	therefore	RB
cord-023443-pvz7dll9	755	24	rather	rather	RB
cord-023443-pvz7dll9	755	25	M2	M2	NNP
cord-023443-pvz7dll9	755	26	associated	associate	VBN
cord-023443-pvz7dll9	755	27	.	.	.
cord-023443-pvz7dll9	756	1	Overall	overall	RB
cord-023443-pvz7dll9	756	2	,	,	,
cord-023443-pvz7dll9	756	3	our	-PRON-	PRP$
cord-023443-pvz7dll9	756	4	data	datum	NNS
cord-023443-pvz7dll9	756	5	provide	provide	VBP
cord-023443-pvz7dll9	756	6	new	new	JJ
cord-023443-pvz7dll9	756	7	markers	marker	NNS
cord-023443-pvz7dll9	756	8	for	for	IN
cord-023443-pvz7dll9	756	9	MSC	MSC	NNP
cord-023443-pvz7dll9	756	10	in	in	IN
cord-023443-pvz7dll9	756	11	cancer	cancer	NN
cord-023443-pvz7dll9	756	12	and	and	CC
cord-023443-pvz7dll9	756	13	further	further	RB
cord-023443-pvz7dll9	756	14	establish	establish	VB
cord-023443-pvz7dll9	756	15	their	-PRON-	PRP$
cord-023443-pvz7dll9	756	16	M2	M2	NNP
cord-023443-pvz7dll9	756	17	activation	activation	NN
cord-023443-pvz7dll9	756	18	state	state	NN
cord-023443-pvz7dll9	756	19	.	.	.
cord-023443-pvz7dll9	757	1	study	study	NN
cord-023443-pvz7dll9	757	2	.	.	.
cord-023443-pvz7dll9	758	1	Only	only	RB
cord-023443-pvz7dll9	758	2	SP	SP	NNP
cord-023443-pvz7dll9	758	3	-	-	HYPH
cord-023443-pvz7dll9	758	4	A	A	NNP
cord-023443-pvz7dll9	758	5	showed	show	VBD
cord-023443-pvz7dll9	758	6	a	a	DT
cord-023443-pvz7dll9	758	7	significant	significant	JJ
cord-023443-pvz7dll9	758	8	expression	expression	NN
cord-023443-pvz7dll9	758	9	in	in	IN
cord-023443-pvz7dll9	758	10	normal	normal	JJ
cord-023443-pvz7dll9	758	11	mucosa	mucosa	NN
cord-023443-pvz7dll9	758	12	which	which	WDT
cord-023443-pvz7dll9	758	13	was	be	VBD
cord-023443-pvz7dll9	758	14	downregulated	downregulate	VBN
cord-023443-pvz7dll9	758	15	in	in	IN
cord-023443-pvz7dll9	758	16	CRC	CRC	NNP
cord-023443-pvz7dll9	758	17	.	.	.
cord-023443-pvz7dll9	759	1	As	as	IN
cord-023443-pvz7dll9	759	2	the	the	DT
cord-023443-pvz7dll9	759	3	absolute	absolute	JJ
cord-023443-pvz7dll9	759	4	signal	signal	JJ
cord-023443-pvz7dll9	759	5	level	level	NN
cord-023443-pvz7dll9	759	6	was	be	VBD
cord-023443-pvz7dll9	759	7	below	below	IN
cord-023443-pvz7dll9	759	8	the	the	DT
cord-023443-pvz7dll9	759	9	noise	noise	NN
cord-023443-pvz7dll9	759	10	threshold	threshold	NN
cord-023443-pvz7dll9	759	11	,	,	,
cord-023443-pvz7dll9	759	12	these	these	DT
cord-023443-pvz7dll9	759	13	results	result	NNS
cord-023443-pvz7dll9	759	14	have	have	VBP
cord-023443-pvz7dll9	759	15	to	to	TO
cord-023443-pvz7dll9	759	16	be	be	VB
cord-023443-pvz7dll9	759	17	interpreted	interpret	VBN
cord-023443-pvz7dll9	759	18	with	with	IN
cord-023443-pvz7dll9	759	19	caution	caution	NN
cord-023443-pvz7dll9	759	20	and	and	CC
cord-023443-pvz7dll9	759	21	require	require	VB
cord-023443-pvz7dll9	759	22	confirmation	confirmation	NN
cord-023443-pvz7dll9	759	23	by	by	IN
cord-023443-pvz7dll9	759	24	direct	direct	NNP
cord-023443-pvz7dll9	759	25	measurenment	measurenment	NNP
cord-023443-pvz7dll9	759	26	of	of	IN
cord-023443-pvz7dll9	759	27	the	the	DT
cord-023443-pvz7dll9	759	28	proteins	protein	NNS
cord-023443-pvz7dll9	759	29	.	.	.
cord-023443-pvz7dll9	760	1	Our	-PRON-	PRP$
cord-023443-pvz7dll9	760	2	results	result	NNS
cord-023443-pvz7dll9	760	3	suggest	suggest	VBP
cord-023443-pvz7dll9	760	4	that	that	IN
cord-023443-pvz7dll9	760	5	there	there	EX
cord-023443-pvz7dll9	760	6	is	be	VBZ
cord-023443-pvz7dll9	760	7	no	no	DT
cord-023443-pvz7dll9	760	8	major	major	JJ
cord-023443-pvz7dll9	760	9	role	role	NN
cord-023443-pvz7dll9	760	10	for	for	IN
cord-023443-pvz7dll9	760	11	the	the	DT
cord-023443-pvz7dll9	760	12	human	human	JJ
cord-023443-pvz7dll9	760	13	collectins	collectin	NNS
cord-023443-pvz7dll9	760	14	in	in	IN
cord-023443-pvz7dll9	760	15	colorectal	colorectal	JJ
cord-023443-pvz7dll9	760	16	cancer	cancer	NN
cord-023443-pvz7dll9	760	17	.	.	.
cord-023443-pvz7dll9	760	18	 	 	_SP
cord-023443-pvz7dll9	761	1	Tetramerization	Tetramerization	NNP
cord-023443-pvz7dll9	761	2	is	be	VBZ
cord-023443-pvz7dll9	761	3	visualized	visualize	VBN
cord-023443-pvz7dll9	761	4	by	by	IN
cord-023443-pvz7dll9	761	5	SDS	SDS	NNP
cord-023443-pvz7dll9	761	6	-	-	HYPH
cord-023443-pvz7dll9	761	7	PAGE	PAGE	NNP
cord-023443-pvz7dll9	761	8	.	.	.
cord-023443-pvz7dll9	762	1	Conclusion	conclusion	NN
cord-023443-pvz7dll9	762	2	:	:	:
cord-023443-pvz7dll9	763	1	An	an	DT
cord-023443-pvz7dll9	763	2	effective	effective	JJ
cord-023443-pvz7dll9	763	3	method	method	NN
cord-023443-pvz7dll9	763	4	for	for	IN
cord-023443-pvz7dll9	763	5	the	the	DT
cord-023443-pvz7dll9	763	6	production	production	NN
cord-023443-pvz7dll9	763	7	of	of	IN
cord-023443-pvz7dll9	763	8	highly	highly	RB
cord-023443-pvz7dll9	763	9	pure	pure	JJ
cord-023443-pvz7dll9	763	10	MHC	MHC	NNP
cord-023443-pvz7dll9	764	1	I	-PRON-	PRP
cord-023443-pvz7dll9	764	2	molecules	molecule	NNS
cord-023443-pvz7dll9	764	3	has	have	VBZ
cord-023443-pvz7dll9	764	4	been	be	VBN
cord-023443-pvz7dll9	764	5	applied	apply	VBN
cord-023443-pvz7dll9	764	6	to	to	IN
cord-023443-pvz7dll9	764	7	HLA	HLA	NNP
cord-023443-pvz7dll9	764	8	-	-	HYPH
cord-023443-pvz7dll9	764	9	B*1501	B*1501	NNP
cord-023443-pvz7dll9	764	10	and	and	CC
cord-023443-pvz7dll9	764	11	HLA	HLA	NNP
cord-023443-pvz7dll9	764	12	-	-	HYPH
cord-023443-pvz7dll9	764	13	B*5801	B*5801	NNP
cord-023443-pvz7dll9	764	14	,	,	,
cord-023443-pvz7dll9	764	15	and	and	CC
cord-023443-pvz7dll9	764	16	RIA	RIA	NNP
cord-023443-pvz7dll9	764	17	and	and	CC
cord-023443-pvz7dll9	764	18	ELISA	ELISA	NNP
cord-023443-pvz7dll9	764	19	binding	bind	VBG
cord-023443-pvz7dll9	764	20	assays	assay	NNS
cord-023443-pvz7dll9	764	21	for	for	IN
cord-023443-pvz7dll9	764	22	those	those	DT
cord-023443-pvz7dll9	764	23	alleles	allele	NNS
cord-023443-pvz7dll9	764	24	have	have	VBP
cord-023443-pvz7dll9	764	25	been	be	VBN
cord-023443-pvz7dll9	764	26	established	establish	VBN
cord-023443-pvz7dll9	764	27	Background	background	NN
cord-023443-pvz7dll9	764	28	:	:	:
cord-023443-pvz7dll9	764	29	Proliferation	proliferation	NN
cord-023443-pvz7dll9	764	30	,	,	,
cord-023443-pvz7dll9	764	31	differentiation	differentiation	NN
cord-023443-pvz7dll9	764	32	and	and	CC
cord-023443-pvz7dll9	764	33	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	764	34	are	be	VBP
cord-023443-pvz7dll9	764	35	essential	essential	JJ
cord-023443-pvz7dll9	764	36	processes	process	NNS
cord-023443-pvz7dll9	764	37	in	in	IN
cord-023443-pvz7dll9	764	38	the	the	DT
cord-023443-pvz7dll9	764	39	normal	normal	JJ
cord-023443-pvz7dll9	764	40	functions	function	NNS
cord-023443-pvz7dll9	764	41	of	of	IN
cord-023443-pvz7dll9	764	42	the	the	DT
cord-023443-pvz7dll9	764	43	mammary	mammary	JJ
cord-023443-pvz7dll9	764	44	epithelium	epithelium	NN
cord-023443-pvz7dll9	764	45	.	.	.
cord-023443-pvz7dll9	765	1	The	the	DT
cord-023443-pvz7dll9	765	2	hypothesis	hypothesis	NN
cord-023443-pvz7dll9	765	3	examined	examine	VBD
cord-023443-pvz7dll9	765	4	in	in	IN
cord-023443-pvz7dll9	765	5	this	this	DT
cord-023443-pvz7dll9	765	6	study	study	NN
cord-023443-pvz7dll9	765	7	is	be	VBZ
cord-023443-pvz7dll9	765	8	that	that	IN
cord-023443-pvz7dll9	765	9	the	the	DT
cord-023443-pvz7dll9	765	10	transcription	transcription	NN
cord-023443-pvz7dll9	765	11	factor	factor	NN
cord-023443-pvz7dll9	765	12	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	765	13	is	be	VBZ
cord-023443-pvz7dll9	765	14	critically	critically	RB
cord-023443-pvz7dll9	765	15	important	important	JJ
cord-023443-pvz7dll9	765	16	not	not	RB
cord-023443-pvz7dll9	765	17	only	only	RB
cord-023443-pvz7dll9	765	18	for	for	IN
cord-023443-pvz7dll9	765	19	regulating	regulate	VBG
cord-023443-pvz7dll9	765	20	B	b	NN
cord-023443-pvz7dll9	765	21	-	-	HYPH
cord-023443-pvz7dll9	765	22	cell	cell	NN
cord-023443-pvz7dll9	765	23	growth	growth	NN
cord-023443-pvz7dll9	765	24	and	and	CC
cord-023443-pvz7dll9	765	25	development	development	NN
cord-023443-pvz7dll9	765	26	but	but	CC
cord-023443-pvz7dll9	765	27	also	also	RB
cord-023443-pvz7dll9	765	28	for	for	IN
cord-023443-pvz7dll9	765	29	mammary	mammary	JJ
cord-023443-pvz7dll9	765	30	epithelial	epithelial	JJ
cord-023443-pvz7dll9	765	31	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	765	32	.	.	.
cord-023443-pvz7dll9	766	1	Methodology	methodology	NN
cord-023443-pvz7dll9	766	2	:	:	:
cord-023443-pvz7dll9	767	1	Twenty	twenty	CD
cord-023443-pvz7dll9	767	2	breast	breast	NN
cord-023443-pvz7dll9	767	3	cancer	cancer	NN
cord-023443-pvz7dll9	767	4	cases	case	NNS
cord-023443-pvz7dll9	767	5	and	and	CC
cord-023443-pvz7dll9	767	6	31	31	CD
cord-023443-pvz7dll9	767	7	healthy	healthy	JJ
cord-023443-pvz7dll9	767	8	controls	control	NNS
cord-023443-pvz7dll9	767	9	were	be	VBD
cord-023443-pvz7dll9	767	10	used	use	VBN
cord-023443-pvz7dll9	767	11	to	to	TO
cord-023443-pvz7dll9	767	12	investigate	investigate	VB
cord-023443-pvz7dll9	767	13	whether	whether	IN
cord-023443-pvz7dll9	767	14	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	767	15	protein	protein	NN
cord-023443-pvz7dll9	767	16	in	in	IN
cord-023443-pvz7dll9	767	17	involved	involve	VBN
cord-023443-pvz7dll9	767	18	in	in	IN
cord-023443-pvz7dll9	767	19	breast	breast	NN
cord-023443-pvz7dll9	767	20	cancer	cancer	NN
cord-023443-pvz7dll9	767	21	(	(	-LRB-
cord-023443-pvz7dll9	767	22	grade	grade	NN
cord-023443-pvz7dll9	767	23	III	III	NNP
cord-023443-pvz7dll9	767	24	)	)	-RRB-
cord-023443-pvz7dll9	767	25	.	.	.
cord-023443-pvz7dll9	768	1	Full	full	JJ
cord-023443-pvz7dll9	768	2	length	length	NN
cord-023443-pvz7dll9	769	1	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	769	2	cDNA	cdna	NN
cord-023443-pvz7dll9	769	3	was	be	VBD
cord-023443-pvz7dll9	769	4	retrovirally	retrovirally	RB
cord-023443-pvz7dll9	769	5	transduced	transduce	VBN
cord-023443-pvz7dll9	769	6	into	into	IN
cord-023443-pvz7dll9	769	7	EpH-4	EpH-4	NNP
cord-023443-pvz7dll9	769	8	cell	cell	NN
cord-023443-pvz7dll9	769	9	line	line	NN
cord-023443-pvz7dll9	769	10	.	.	.
cord-023443-pvz7dll9	770	1	We	-PRON-	PRP
cord-023443-pvz7dll9	770	2	then	then	RB
cord-023443-pvz7dll9	770	3	used	use	VBD
cord-023443-pvz7dll9	770	4	flow	flow	NN
cord-023443-pvz7dll9	770	5	cytometry	cytometry	NN
cord-023443-pvz7dll9	770	6	of	of	IN
cord-023443-pvz7dll9	770	7	BrdUrd	BrdUrd	NNP
cord-023443-pvz7dll9	770	8	-	-	HYPH
cord-023443-pvz7dll9	770	9	stained	stain	VBN
cord-023443-pvz7dll9	770	10	cells	cell	NNS
cord-023443-pvz7dll9	770	11	to	to	TO
cord-023443-pvz7dll9	770	12	investigate	investigate	VB
cord-023443-pvz7dll9	770	13	the	the	DT
cord-023443-pvz7dll9	770	14	cell	cell	NN
cord-023443-pvz7dll9	770	15	-	-	HYPH
cord-023443-pvz7dll9	770	16	cycle	cycle	NN
cord-023443-pvz7dll9	770	17	duration	duration	NN
cord-023443-pvz7dll9	770	18	of	of	IN
cord-023443-pvz7dll9	770	19	the	the	DT
cord-023443-pvz7dll9	770	20	control	control	NN
cord-023443-pvz7dll9	770	21	and	and	CC
cord-023443-pvz7dll9	770	22	transduced	transduce	VBD
cord-023443-pvz7dll9	770	23	cell	cell	NN
cord-023443-pvz7dll9	770	24	lines	line	NNS
cord-023443-pvz7dll9	770	25	.	.	.
cord-023443-pvz7dll9	771	1	TUNEL	TUNEL	NNP
cord-023443-pvz7dll9	771	2	was	be	VBD
cord-023443-pvz7dll9	771	3	used	use	VBN
cord-023443-pvz7dll9	771	4	as	as	IN
cord-023443-pvz7dll9	771	5	a	a	DT
cord-023443-pvz7dll9	771	6	marker	marker	NN
cord-023443-pvz7dll9	771	7	of	of	IN
cord-023443-pvz7dll9	771	8	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	771	9	to	to	TO
cord-023443-pvz7dll9	771	10	find	find	VB
cord-023443-pvz7dll9	771	11	out	out	RP
cord-023443-pvz7dll9	771	12	differences	difference	NNS
cord-023443-pvz7dll9	771	13	in	in	IN
cord-023443-pvz7dll9	771	14	the	the	DT
cord-023443-pvz7dll9	771	15	frequencies	frequency	NNS
cord-023443-pvz7dll9	771	16	of	of	IN
cord-023443-pvz7dll9	771	17	apoptotic	apoptotic	JJ
cord-023443-pvz7dll9	771	18	cells	cell	NNS
cord-023443-pvz7dll9	771	19	in	in	IN
cord-023443-pvz7dll9	771	20	the	the	DT
cord-023443-pvz7dll9	771	21	control	control	NN
cord-023443-pvz7dll9	771	22	and	and	CC
cord-023443-pvz7dll9	771	23	transduced	transduce	VBD
cord-023443-pvz7dll9	771	24	cell	cell	NN
cord-023443-pvz7dll9	771	25	lines	line	NNS
cord-023443-pvz7dll9	771	26	.	.	.
cord-023443-pvz7dll9	772	1	Finally	finally	RB
cord-023443-pvz7dll9	772	2	,	,	,
cord-023443-pvz7dll9	772	3	immunohistochemistry	immunohistochemistry	NN
cord-023443-pvz7dll9	772	4	staining	staining	NN
cord-023443-pvz7dll9	772	5	was	be	VBD
cord-023443-pvz7dll9	772	6	performed	perform	VBN
cord-023443-pvz7dll9	772	7	to	to	TO
cord-023443-pvz7dll9	772	8	detect	detect	VB
cord-023443-pvz7dll9	772	9	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	772	10	in	in	IN
cord-023443-pvz7dll9	772	11	breast	breast	NN
cord-023443-pvz7dll9	772	12	cancer	cancer	NN
cord-023443-pvz7dll9	772	13	(	(	-LRB-
cord-023443-pvz7dll9	772	14	III	III	NNP
cord-023443-pvz7dll9	772	15	)	)	-RRB-
cord-023443-pvz7dll9	772	16	.	.	.
cord-023443-pvz7dll9	773	1	Results	result	NNS
cord-023443-pvz7dll9	773	2	:	:	:
cord-023443-pvz7dll9	773	3	Restoration	restoration	NN
cord-023443-pvz7dll9	773	4	of	of	IN
cord-023443-pvz7dll9	773	5	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	773	6	into	into	IN
cord-023443-pvz7dll9	773	7	EpH-4	EpH-4	NNP
cord-023443-pvz7dll9	773	8	cells	cell	NNS
cord-023443-pvz7dll9	774	1	not	not	RB
cord-023443-pvz7dll9	774	2	only	only	RB
cord-023443-pvz7dll9	774	3	inhibits	inhibit	VBZ
cord-023443-pvz7dll9	774	4	apoptosis	apoptosis	NN
cord-023443-pvz7dll9	774	5	but	but	CC
cord-023443-pvz7dll9	774	6	also	also	RB
cord-023443-pvz7dll9	774	7	prolongs	prolong	VBZ
cord-023443-pvz7dll9	774	8	the	the	DT
cord-023443-pvz7dll9	774	9	cell	cell	NN
cord-023443-pvz7dll9	774	10	cycle	cycle	NN
cord-023443-pvz7dll9	774	11	and	and	CC
cord-023443-pvz7dll9	774	12	results	result	NNS
cord-023443-pvz7dll9	774	13	in	in	IN
cord-023443-pvz7dll9	774	14	increased	increase	VBN
cord-023443-pvz7dll9	774	15	cell	cell	NN
cord-023443-pvz7dll9	774	16	size	size	NN
cord-023443-pvz7dll9	774	17	and	and	CC
cord-023443-pvz7dll9	774	18	protein	protein	NN
cord-023443-pvz7dll9	774	19	content	content	NN
cord-023443-pvz7dll9	774	20	.	.	.
cord-023443-pvz7dll9	775	1	The	the	DT
cord-023443-pvz7dll9	775	2	results	result	NNS
cord-023443-pvz7dll9	775	3	also	also	RB
cord-023443-pvz7dll9	775	4	indicated	indicate	VBD
cord-023443-pvz7dll9	775	5	that	that	IN
cord-023443-pvz7dll9	775	6	the	the	DT
cord-023443-pvz7dll9	775	7	cell	cell	NN
cord-023443-pvz7dll9	775	8	-	-	HYPH
cord-023443-pvz7dll9	775	9	cycle	cycle	NN
cord-023443-pvz7dll9	775	10	time	time	NN
cord-023443-pvz7dll9	775	11	of	of	IN
cord-023443-pvz7dll9	775	12	BCL-6-transduced	BCL-6-transduced	NNP
cord-023443-pvz7dll9	775	13	EpH-4	EpH-4	NNP
cord-023443-pvz7dll9	775	14	cells	cell	NNS
cord-023443-pvz7dll9	775	15	is	be	VBZ
cord-023443-pvz7dll9	775	16	prolonged	prolong	VBN
cord-023443-pvz7dll9	775	17	by	by	IN
cord-023443-pvz7dll9	775	18	about	about	RB
cord-023443-pvz7dll9	775	19	3	3	CD
cord-023443-pvz7dll9	775	20	h	h	NN
cord-023443-pvz7dll9	775	21	,	,	,
cord-023443-pvz7dll9	775	22	presumably	presumably	RB
cord-023443-pvz7dll9	775	23	as	as	IN
cord-023443-pvz7dll9	775	24	a	a	DT
cord-023443-pvz7dll9	775	25	result	result	NN
cord-023443-pvz7dll9	775	26	of	of	IN
cord-023443-pvz7dll9	775	27	the	the	DT
cord-023443-pvz7dll9	775	28	action	action	NN
cord-023443-pvz7dll9	775	29	of	of	IN
cord-023443-pvz7dll9	775	30	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	775	31	at	at	IN
cord-023443-pvz7dll9	775	32	the	the	DT
cord-023443-pvz7dll9	775	33	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	775	34	at	at	IN
cord-023443-pvz7dll9	775	35	the	the	DT
cord-023443-pvz7dll9	775	36	G1	G1	NNP
cord-023443-pvz7dll9	775	37	/	/	SYM
cord-023443-pvz7dll9	775	38	S	S	NNP
cord-023443-pvz7dll9	775	39	transition	transition	NN
cord-023443-pvz7dll9	775	40	.	.	.
cord-023443-pvz7dll9	776	1	We	-PRON-	PRP
cord-023443-pvz7dll9	776	2	found	find	VBD
cord-023443-pvz7dll9	776	3	differences	difference	NNS
cord-023443-pvz7dll9	776	4	in	in	IN
cord-023443-pvz7dll9	776	5	the	the	DT
cord-023443-pvz7dll9	776	6	frequencies	frequency	NNS
cord-023443-pvz7dll9	776	7	of	of	IN
cord-023443-pvz7dll9	776	8	viable	viable	JJ
cord-023443-pvz7dll9	776	9	and	and	CC
cord-023443-pvz7dll9	776	10	apoptotic	apoptotic	JJ
cord-023443-pvz7dll9	776	11	cells	cell	NNS
cord-023443-pvz7dll9	776	12	in	in	IN
cord-023443-pvz7dll9	776	13	cultures	culture	NNS
cord-023443-pvz7dll9	776	14	of	of	IN
cord-023443-pvz7dll9	776	15	the	the	DT
cord-023443-pvz7dll9	776	16	parent	parent	NN
cord-023443-pvz7dll9	776	17	EpH-4	eph-4	PRP
cord-023443-pvz7dll9	776	18	cells	cell	NNS
cord-023443-pvz7dll9	776	19	,	,	,
cord-023443-pvz7dll9	776	20	control	control	NN
cord-023443-pvz7dll9	776	21	-	-	HYPH
cord-023443-pvz7dll9	776	22	transduced	transduce	VBN
cord-023443-pvz7dll9	776	23	EpH-4	EpH-4	NNP
cord-023443-pvz7dll9	776	24	cells	cell	NNS
cord-023443-pvz7dll9	776	25	and	and	CC
cord-023443-pvz7dll9	776	26	BCL-6-transduced	BCL-6-transduced	NNP
cord-023443-pvz7dll9	776	27	EpH-4	EpH-4	NNP
cord-023443-pvz7dll9	776	28	cells	cell	NNS
cord-023443-pvz7dll9	776	29	.	.	.
cord-023443-pvz7dll9	777	1	Consistently	consistently	RB
cord-023443-pvz7dll9	777	2	,	,	,
cord-023443-pvz7dll9	777	3	we	-PRON-	PRP
cord-023443-pvz7dll9	777	4	demonstrated	demonstrate	VBD
cord-023443-pvz7dll9	777	5	that	that	IN
cord-023443-pvz7dll9	777	6	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	777	7	is	be	VBZ
cord-023443-pvz7dll9	777	8	expressed	express	VBN
cord-023443-pvz7dll9	777	9	in	in	IN
cord-023443-pvz7dll9	777	10	90	90	CD
cord-023443-pvz7dll9	777	11	%	%	NN
cord-023443-pvz7dll9	777	12	of	of	IN
cord-023443-pvz7dll9	777	13	high	high	JJ
cord-023443-pvz7dll9	777	14	grade	grade	NN
cord-023443-pvz7dll9	777	15	of	of	IN
cord-023443-pvz7dll9	777	16	breast	breast	NN
cord-023443-pvz7dll9	777	17	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	777	18	,	,	,
cord-023443-pvz7dll9	777	19	which	which	WDT
cord-023443-pvz7dll9	777	20	is	be	VBZ
cord-023443-pvz7dll9	777	21	considered	consider	VBN
cord-023443-pvz7dll9	777	22	as	as	IN
cord-023443-pvz7dll9	777	23	the	the	DT
cord-023443-pvz7dll9	777	24	most	most	RBS
cord-023443-pvz7dll9	777	25	aggressive	aggressive	JJ
cord-023443-pvz7dll9	777	26	of	of	IN
cord-023443-pvz7dll9	777	27	tumours	tumour	NNS
cord-023443-pvz7dll9	777	28	.	.	.
cord-023443-pvz7dll9	778	1	Conclusion	conclusion	NN
cord-023443-pvz7dll9	778	2	:	:	:
cord-023443-pvz7dll9	779	1	Together	together	RB
cord-023443-pvz7dll9	779	2	,	,	,
cord-023443-pvz7dll9	779	3	these	these	DT
cord-023443-pvz7dll9	779	4	results	result	NNS
cord-023443-pvz7dll9	779	5	suggest	suggest	VBP
cord-023443-pvz7dll9	779	6	that	that	IN
cord-023443-pvz7dll9	779	7	BCL-6	BCL-6	NNP
cord-023443-pvz7dll9	779	8	is	be	VBZ
cord-023443-pvz7dll9	779	9	likely	likely	JJ
cord-023443-pvz7dll9	779	10	to	to	TO
cord-023443-pvz7dll9	779	11	be	be	VB
cord-023443-pvz7dll9	779	12	involved	involve	VBN
cord-023443-pvz7dll9	779	13	in	in	IN
cord-023443-pvz7dll9	779	14	mammary	mammary	JJ
cord-023443-pvz7dll9	779	15	gland	gland	NN
cord-023443-pvz7dll9	779	16	development	development	NN
cord-023443-pvz7dll9	779	17	and	and	CC
cord-023443-pvz7dll9	779	18	carcinogenesis	carcinogenesis	NN
cord-023443-pvz7dll9	779	19	.	.	.
cord-023443-pvz7dll9	780	1	Inflammatory	inflammatory	JJ
cord-023443-pvz7dll9	780	2	cytokines	cytokine	NNS
cord-023443-pvz7dll9	780	3	have	have	VBP
cord-023443-pvz7dll9	780	4	a	a	DT
cord-023443-pvz7dll9	780	5	critical	critical	JJ
cord-023443-pvz7dll9	780	6	role	role	NN
cord-023443-pvz7dll9	780	7	in	in	IN
cord-023443-pvz7dll9	780	8	modulation	modulation	NN
cord-023443-pvz7dll9	780	9	of	of	IN
cord-023443-pvz7dll9	780	10	both	both	DT
cord-023443-pvz7dll9	780	11	innate	innate	JJ
cord-023443-pvz7dll9	780	12	and	and	CC
cord-023443-pvz7dll9	780	13	adaptive	adaptive	JJ
cord-023443-pvz7dll9	780	14	immunity	immunity	NN
cord-023443-pvz7dll9	780	15	in	in	IN
cord-023443-pvz7dll9	780	16	response	response	NN
cord-023443-pvz7dll9	780	17	to	to	IN
cord-023443-pvz7dll9	780	18	foreign	foreign	JJ
cord-023443-pvz7dll9	780	19	antigen	antigen	NN
cord-023443-pvz7dll9	780	20	.	.	.
cord-023443-pvz7dll9	781	1	They	-PRON-	PRP
cord-023443-pvz7dll9	781	2	also	also	RB
cord-023443-pvz7dll9	781	3	play	play	VBP
cord-023443-pvz7dll9	781	4	an	an	DT
cord-023443-pvz7dll9	781	5	important	important	JJ
cord-023443-pvz7dll9	781	6	role	role	NN
cord-023443-pvz7dll9	781	7	in	in	IN
cord-023443-pvz7dll9	781	8	anticancer	anticancer	JJ
cord-023443-pvz7dll9	781	9	immunity	immunity	NN
cord-023443-pvz7dll9	781	10	.	.	.
cord-023443-pvz7dll9	782	1	For	for	IN
cord-023443-pvz7dll9	782	2	example	example	NN
cord-023443-pvz7dll9	782	3	,	,	,
cord-023443-pvz7dll9	782	4	they	-PRON-	PRP
cord-023443-pvz7dll9	782	5	can	can	MD
cord-023443-pvz7dll9	782	6	promote	promote	VB
cord-023443-pvz7dll9	782	7	cell	cell	NN
cord-023443-pvz7dll9	782	8	-	-	HYPH
cord-023443-pvz7dll9	782	9	mediated	mediate	VBN
cord-023443-pvz7dll9	782	10	immunity	immunity	NN
cord-023443-pvz7dll9	782	11	against	against	IN
cord-023443-pvz7dll9	782	12	cancer	cancer	NN
cord-023443-pvz7dll9	782	13	cells	cell	NNS
cord-023443-pvz7dll9	782	14	.	.	.
cord-023443-pvz7dll9	783	1	With	with	IN
cord-023443-pvz7dll9	783	2	their	-PRON-	PRP$
cord-023443-pvz7dll9	783	3	immunostimulatory	immunostimulatory	NN
cord-023443-pvz7dll9	783	4	effects	effect	NNS
cord-023443-pvz7dll9	783	5	,	,	,
cord-023443-pvz7dll9	783	6	these	these	DT
cord-023443-pvz7dll9	783	7	cytokines	cytokine	NNS
cord-023443-pvz7dll9	783	8	are	be	VBP
cord-023443-pvz7dll9	783	9	being	be	VBG
cord-023443-pvz7dll9	783	10	tested	test	VBN
cord-023443-pvz7dll9	783	11	for	for	IN
cord-023443-pvz7dll9	783	12	cancer	cancer	NN
cord-023443-pvz7dll9	783	13	treatment	treatment	NN
cord-023443-pvz7dll9	783	14	in	in	IN
cord-023443-pvz7dll9	783	15	the	the	DT
cord-023443-pvz7dll9	783	16	form	form	NN
cord-023443-pvz7dll9	783	17	of	of	IN
cord-023443-pvz7dll9	783	18	DNA	dna	NN
cord-023443-pvz7dll9	783	19	vaccine	vaccine	NN
cord-023443-pvz7dll9	783	20	or	or	CC
cord-023443-pvz7dll9	783	21	adjuvant	adjuvant	JJ
cord-023443-pvz7dll9	783	22	or	or	CC
cord-023443-pvz7dll9	783	23	therapeutic	therapeutic	JJ
cord-023443-pvz7dll9	783	24	cytokines	cytokine	NNS
cord-023443-pvz7dll9	783	25	.	.	.
cord-023443-pvz7dll9	784	1	Direct	direct	JJ
cord-023443-pvz7dll9	784	2	effect	effect	NN
cord-023443-pvz7dll9	784	3	of	of	IN
cord-023443-pvz7dll9	784	4	these	these	DT
cord-023443-pvz7dll9	784	5	cytokines	cytokine	NNS
cord-023443-pvz7dll9	784	6	on	on	IN
cord-023443-pvz7dll9	784	7	cancer	cancer	NN
cord-023443-pvz7dll9	784	8	cell	cell	NN
cord-023443-pvz7dll9	784	9	,	,	,
cord-023443-pvz7dll9	784	10	however	however	RB
cord-023443-pvz7dll9	784	11	,	,	,
cord-023443-pvz7dll9	784	12	is	be	VBZ
cord-023443-pvz7dll9	784	13	still	still	RB
cord-023443-pvz7dll9	784	14	unclear	unclear	JJ
cord-023443-pvz7dll9	784	15	.	.	.
cord-023443-pvz7dll9	785	1	In	in	IN
cord-023443-pvz7dll9	785	2	this	this	DT
cord-023443-pvz7dll9	785	3	project	project	NN
cord-023443-pvz7dll9	785	4	,	,	,
cord-023443-pvz7dll9	785	5	we	-PRON-	PRP
cord-023443-pvz7dll9	785	6	investigated	investigate	VBD
cord-023443-pvz7dll9	785	7	whether	whether	IN
cord-023443-pvz7dll9	785	8	IL-1	IL-1	NNP
cord-023443-pvz7dll9	785	9	(	(	-LRB-
cord-023443-pvz7dll9	785	10	and	and	CC
cord-023443-pvz7dll9	785	11	IL-18	IL-18	NNP
cord-023443-pvz7dll9	785	12	can	can	MD
cord-023443-pvz7dll9	785	13	modulate	modulate	VB
cord-023443-pvz7dll9	785	14	cancer	cancer	NN
cord-023443-pvz7dll9	785	15	cell	cell	NN
cord-023443-pvz7dll9	785	16	proliferation	proliferation	NN
cord-023443-pvz7dll9	785	17	.	.	.
cord-023443-pvz7dll9	786	1	We	-PRON-	PRP
cord-023443-pvz7dll9	786	2	employed	employ	VBD
cord-023443-pvz7dll9	786	3	a	a	DT
cord-023443-pvz7dll9	786	4	simple	simple	JJ
cord-023443-pvz7dll9	786	5	nonradioactive	nonradioactive	JJ
cord-023443-pvz7dll9	786	6	proliferation	proliferation	NN
cord-023443-pvz7dll9	786	7	(	(	-LRB-
cord-023443-pvz7dll9	786	8	MTT	MTT	NNP
cord-023443-pvz7dll9	786	9	)	)	-RRB-
cord-023443-pvz7dll9	786	10	assay	assay	NN
cord-023443-pvz7dll9	786	11	and	and	CC
cord-023443-pvz7dll9	786	12	detection	detection	NN
cord-023443-pvz7dll9	786	13	of	of	IN
cord-023443-pvz7dll9	786	14	lactate	lactate	NN
cord-023443-pvz7dll9	786	15	dehydrogenase	dehydrogenase	NN
cord-023443-pvz7dll9	786	16	(	(	-LRB-
cord-023443-pvz7dll9	786	17	LDH	LDH	NNP
cord-023443-pvz7dll9	786	18	)	)	-RRB-
cord-023443-pvz7dll9	786	19	to	to	TO
cord-023443-pvz7dll9	786	20	test	test	VB
cord-023443-pvz7dll9	786	21	the	the	DT
cord-023443-pvz7dll9	786	22	effect	effect	NN
cord-023443-pvz7dll9	786	23	of	of	IN
cord-023443-pvz7dll9	786	24	these	these	DT
cord-023443-pvz7dll9	786	25	recombinant	recombinant	JJ
cord-023443-pvz7dll9	786	26	human	human	JJ
cord-023443-pvz7dll9	786	27	cytokines	cytokine	NNS
cord-023443-pvz7dll9	786	28	on	on	IN
cord-023443-pvz7dll9	786	29	various	various	JJ
cord-023443-pvz7dll9	786	30	cancer	cancer	NN
cord-023443-pvz7dll9	786	31	cell	cell	NN
cord-023443-pvz7dll9	786	32	lines	line	NNS
cord-023443-pvz7dll9	786	33	,	,	,
cord-023443-pvz7dll9	786	34	including	include	VBG
cord-023443-pvz7dll9	786	35	breast	breast	NN
cord-023443-pvz7dll9	786	36	cancer	cancer	NN
cord-023443-pvz7dll9	786	37	cell	cell	NN
cord-023443-pvz7dll9	786	38	line	line	NN
cord-023443-pvz7dll9	786	39	(	(	-LRB-
cord-023443-pvz7dll9	786	40	MCF-7	MCF-7	NNP
cord-023443-pvz7dll9	786	41	)	)	-RRB-
cord-023443-pvz7dll9	786	42	,	,	,
cord-023443-pvz7dll9	786	43	oral	oral	JJ
cord-023443-pvz7dll9	786	44	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	786	45	cell	cell	NN
cord-023443-pvz7dll9	786	46	line	line	NN
cord-023443-pvz7dll9	786	47	(	(	-LRB-
cord-023443-pvz7dll9	786	48	KB	KB	NNP
cord-023443-pvz7dll9	786	49	)	)	-RRB-
cord-023443-pvz7dll9	786	50	,	,	,
cord-023443-pvz7dll9	786	51	colon	colon	NN
cord-023443-pvz7dll9	786	52	cancer	cancer	NN
cord-023443-pvz7dll9	786	53	cell	cell	NN
cord-023443-pvz7dll9	786	54	line	line	NN
cord-023443-pvz7dll9	786	55	(	(	-LRB-
cord-023443-pvz7dll9	786	56	Caco-2	Caco-2	NNP
cord-023443-pvz7dll9	786	57	)	)	-RRB-
cord-023443-pvz7dll9	786	58	and	and	CC
cord-023443-pvz7dll9	786	59	choriocarcinoma	choriocarcinoma	NN
cord-023443-pvz7dll9	786	60	cell	cell	NN
cord-023443-pvz7dll9	786	61	line	line	NN
cord-023443-pvz7dll9	786	62	(	(	-LRB-
cord-023443-pvz7dll9	786	63	Jar	jar	NN
cord-023443-pvz7dll9	786	64	)	)	-RRB-
cord-023443-pvz7dll9	786	65	.	.	.
cord-023443-pvz7dll9	787	1	Cytokines	cytokine	NNS
cord-023443-pvz7dll9	787	2	used	use	VBN
cord-023443-pvz7dll9	787	3	in	in	IN
cord-023443-pvz7dll9	787	4	this	this	DT
cord-023443-pvz7dll9	787	5	study	study	NN
cord-023443-pvz7dll9	787	6	had	have	VBD
cord-023443-pvz7dll9	787	7	both	both	DT
cord-023443-pvz7dll9	787	8	inhibitory	inhibitory	JJ
cord-023443-pvz7dll9	787	9	and	and	CC
cord-023443-pvz7dll9	787	10	stimulatory	stimulatory	JJ
cord-023443-pvz7dll9	787	11	effect	effect	NN
cord-023443-pvz7dll9	787	12	on	on	IN
cord-023443-pvz7dll9	787	13	cell	cell	NN
cord-023443-pvz7dll9	787	14	proliferation	proliferation	NN
cord-023443-pvz7dll9	787	15	.	.	.
cord-023443-pvz7dll9	788	1	Findings	finding	NNS
cord-023443-pvz7dll9	788	2	in	in	IN
cord-023443-pvz7dll9	788	3	this	this	DT
cord-023443-pvz7dll9	788	4	project	project	NN
cord-023443-pvz7dll9	788	5	could	could	MD
cord-023443-pvz7dll9	788	6	provide	provide	VB
cord-023443-pvz7dll9	788	7	an	an	DT
cord-023443-pvz7dll9	788	8	insight	insight	NN
cord-023443-pvz7dll9	788	9	of	of	IN
cord-023443-pvz7dll9	788	10	cancer	cancer	NN
cord-023443-pvz7dll9	788	11	cell	cell	NN
cord-023443-pvz7dll9	788	12	response	response	NN
cord-023443-pvz7dll9	788	13	to	to	IN
cord-023443-pvz7dll9	788	14	these	these	DT
cord-023443-pvz7dll9	788	15	cytokines	cytokine	NNS
cord-023443-pvz7dll9	788	16	and	and	CC
cord-023443-pvz7dll9	788	17	this	this	DT
cord-023443-pvz7dll9	788	18	could	could	MD
cord-023443-pvz7dll9	788	19	lead	lead	VB
cord-023443-pvz7dll9	788	20	to	to	IN
cord-023443-pvz7dll9	788	21	a	a	DT
cord-023443-pvz7dll9	788	22	consideration	consideration	NN
cord-023443-pvz7dll9	788	23	on	on	IN
cord-023443-pvz7dll9	788	24	using	use	VBG
cord-023443-pvz7dll9	788	25	cytokine	cytokine	NN
cord-023443-pvz7dll9	788	26	as	as	IN
cord-023443-pvz7dll9	788	27	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	788	28	for	for	IN
cord-023443-pvz7dll9	788	29	cancer	cancer	NN
cord-023443-pvz7dll9	788	30	treatment	treatment	NN
cord-023443-pvz7dll9	788	31	.	.	.
cord-023443-pvz7dll9	789	1	Capacity	capacity	NN
cord-023443-pvz7dll9	789	2	of	of	IN
cord-023443-pvz7dll9	789	3	AE	AE	NNP
cord-023443-pvz7dll9	789	4	to	to	TO
cord-023443-pvz7dll9	789	5	Modulate	modulate	VB
cord-023443-pvz7dll9	789	6	Nitric	nitric	NN
cord-023443-pvz7dll9	789	7	Oxide	oxide	NN
cord-023443-pvz7dll9	789	8	Production	production	NN
cord-023443-pvz7dll9	789	9	Depended	depend	VBD
cord-023443-pvz7dll9	789	10	on	on	IN
cord-023443-pvz7dll9	789	11	Intercellular	Intercellular	NNP
cord-023443-pvz7dll9	789	12	Contact	Contact	NNP
cord-023443-pvz7dll9	789	13	donor	donor	NN
cord-023443-pvz7dll9	789	14	T	t	NN
cord-023443-pvz7dll9	789	15	cells	cell	NNS
cord-023443-pvz7dll9	789	16	are	be	VBP
cord-023443-pvz7dll9	789	17	involved	involve	VBN
cord-023443-pvz7dll9	789	18	in	in	IN
cord-023443-pvz7dll9	789	19	the	the	DT
cord-023443-pvz7dll9	789	20	antitumour	antitumour	JJ
cord-023443-pvz7dll9	789	21	effects	effect	NNS
cord-023443-pvz7dll9	789	22	observed	observe	VBN
cord-023443-pvz7dll9	789	23	after	after	IN
cord-023443-pvz7dll9	789	24	BMT	BMT	NNP
cord-023443-pvz7dll9	789	25	.	.	.
cord-023443-pvz7dll9	790	1	Thus	thus	RB
cord-023443-pvz7dll9	790	2	,	,	,
cord-023443-pvz7dll9	790	3	patients	patient	NNS
cord-023443-pvz7dll9	790	4	receiving	receive	VBG
cord-023443-pvz7dll9	790	5	T	T	NNP
cord-023443-pvz7dll9	790	6	-	-	HYPH
cord-023443-pvz7dll9	790	7	celldepleted	celldeplete	VBN
cord-023443-pvz7dll9	790	8	BMT	BMT	NNP
cord-023443-pvz7dll9	790	9	have	have	VBP
cord-023443-pvz7dll9	790	10	a	a	DT
cord-023443-pvz7dll9	790	11	higher	high	JJR
cord-023443-pvz7dll9	790	12	risk	risk	NN
cord-023443-pvz7dll9	790	13	of	of	IN
cord-023443-pvz7dll9	790	14	leukaemia	leukaemia	NN
cord-023443-pvz7dll9	790	15	relapse	relapse	NN
cord-023443-pvz7dll9	790	16	compared	compare	VBN
cord-023443-pvz7dll9	790	17	to	to	IN
cord-023443-pvz7dll9	790	18	patients	patient	NNS
cord-023443-pvz7dll9	790	19	receiving	receive	VBG
cord-023443-pvz7dll9	790	20	nonmanipulated	nonmanipulate	VBN
cord-023443-pvz7dll9	790	21	BMT	BMT	NNP
cord-023443-pvz7dll9	790	22	,	,	,
cord-023443-pvz7dll9	790	23	and	and	CC
cord-023443-pvz7dll9	790	24	patients	patient	NNS
cord-023443-pvz7dll9	790	25	experiencing	experience	VBG
cord-023443-pvz7dll9	790	26	graft	graft	NN
cord-023443-pvz7dll9	790	27	-	-	HYPH
cord-023443-pvz7dll9	790	28	versus	versus	IN
cord-023443-pvz7dll9	790	29	-	-	HYPH
cord-023443-pvz7dll9	790	30	host	host	NN
cord-023443-pvz7dll9	790	31	disease	disease	NN
cord-023443-pvz7dll9	790	32	(	(	-LRB-
cord-023443-pvz7dll9	790	33	GVHD	GVHD	NNP
cord-023443-pvz7dll9	790	34	)	)	-RRB-
cord-023443-pvz7dll9	790	35	have	have	VBP
cord-023443-pvz7dll9	790	36	a	a	DT
cord-023443-pvz7dll9	790	37	lower	low	JJR
cord-023443-pvz7dll9	790	38	risk	risk	NN
cord-023443-pvz7dll9	790	39	of	of	IN
cord-023443-pvz7dll9	790	40	disease	disease	NN
cord-023443-pvz7dll9	790	41	relapse	relapse	NN
cord-023443-pvz7dll9	790	42	than	than	IN
cord-023443-pvz7dll9	790	43	patients	patient	NNS
cord-023443-pvz7dll9	790	44	who	who	WP
cord-023443-pvz7dll9	790	45	do	do	VBP
cord-023443-pvz7dll9	790	46	not	not	RB
cord-023443-pvz7dll9	790	47	experience	experience	VB
cord-023443-pvz7dll9	790	48	GVHD	GVHD	NNP
cord-023443-pvz7dll9	790	49	.	.	.
cord-023443-pvz7dll9	791	1	Although	although	IN
cord-023443-pvz7dll9	791	2	the	the	DT
cord-023443-pvz7dll9	791	3	importance	importance	NN
cord-023443-pvz7dll9	791	4	of	of	IN
cord-023443-pvz7dll9	791	5	donor	donor	NN
cord-023443-pvz7dll9	791	6	T	t	NN
cord-023443-pvz7dll9	791	7	cells	cell	NNS
cord-023443-pvz7dll9	791	8	for	for	IN
cord-023443-pvz7dll9	791	9	the	the	DT
cord-023443-pvz7dll9	791	10	curative	curative	JJ
cord-023443-pvz7dll9	791	11	action	action	NN
cord-023443-pvz7dll9	791	12	of	of	IN
cord-023443-pvz7dll9	791	13	BMT	BMT	NNP
cord-023443-pvz7dll9	791	14	has	have	VBZ
cord-023443-pvz7dll9	791	15	been	be	VBN
cord-023443-pvz7dll9	791	16	established	establish	VBN
cord-023443-pvz7dll9	791	17	,	,	,
cord-023443-pvz7dll9	791	18	the	the	DT
cord-023443-pvz7dll9	791	19	exact	exact	JJ
cord-023443-pvz7dll9	791	20	mechanisms	mechanism	NNS
cord-023443-pvz7dll9	791	21	and	and	CC
cord-023443-pvz7dll9	791	22	molecules	molecule	NNS
cord-023443-pvz7dll9	791	23	involved	involve	VBN
cord-023443-pvz7dll9	791	24	in	in	IN
cord-023443-pvz7dll9	791	25	this	this	DT
cord-023443-pvz7dll9	791	26	graft	graft	NN
cord-023443-pvz7dll9	791	27	-	-	HYPH
cord-023443-pvz7dll9	791	28	versus	versus	IN
cord-023443-pvz7dll9	791	29	-	-	HYPH
cord-023443-pvz7dll9	791	30	tumour	tumour	NN
cord-023443-pvz7dll9	791	31	effect	effect	NN
cord-023443-pvz7dll9	791	32	remain	remain	VBP
cord-023443-pvz7dll9	791	33	largely	largely	RB
cord-023443-pvz7dll9	791	34	unknown	unknown	JJ
cord-023443-pvz7dll9	791	35	.	.	.
cord-023443-pvz7dll9	792	1	In	in	IN
cord-023443-pvz7dll9	792	2	a	a	DT
cord-023443-pvz7dll9	792	3	recently	recently	RB
cord-023443-pvz7dll9	792	4	initiated	initiate	VBN
cord-023443-pvz7dll9	792	5	project	project	NN
cord-023443-pvz7dll9	792	6	,	,	,
cord-023443-pvz7dll9	792	7	we	-PRON-	PRP
cord-023443-pvz7dll9	792	8	have	have	VBP
cord-023443-pvz7dll9	792	9	conducted	conduct	VBN
cord-023443-pvz7dll9	792	10	a	a	DT
cord-023443-pvz7dll9	792	11	longitudinal	longitudinal	JJ
cord-023443-pvz7dll9	792	12	study	study	NN
cord-023443-pvz7dll9	792	13	of	of	IN
cord-023443-pvz7dll9	792	14	T	t	NN
cord-023443-pvz7dll9	792	15	-	-	HYPH
cord-023443-pvz7dll9	792	16	cell	cell	NN
cord-023443-pvz7dll9	792	17	clonotypes	clonotype	NNS
cord-023443-pvz7dll9	792	18	in	in	IN
cord-023443-pvz7dll9	792	19	patients	patient	NNS
cord-023443-pvz7dll9	792	20	who	who	WP
cord-023443-pvz7dll9	792	21	received	receive	VBD
cord-023443-pvz7dll9	792	22	peripheral	peripheral	JJ
cord-023443-pvz7dll9	792	23	blood	blood	NN
cord-023443-pvz7dll9	792	24	stem	stem	NN
cord-023443-pvz7dll9	792	25	cell	cell	NN
cord-023443-pvz7dll9	792	26	grafts	graft	NNS
cord-023443-pvz7dll9	792	27	after	after	IN
cord-023443-pvz7dll9	792	28	nonmyeloablative	nonmyeloablative	JJ
cord-023443-pvz7dll9	792	29	conditioning	conditioning	NN
cord-023443-pvz7dll9	792	30	.	.	.
cord-023443-pvz7dll9	793	1	Peripheral	peripheral	JJ
cord-023443-pvz7dll9	793	2	blood	blood	NN
cord-023443-pvz7dll9	793	3	samples	sample	NNS
cord-023443-pvz7dll9	793	4	were	be	VBD
cord-023443-pvz7dll9	793	5	obtained	obtain	VBN
cord-023443-pvz7dll9	793	6	sequentially	sequentially	RB
cord-023443-pvz7dll9	793	7	after	after	IN
cord-023443-pvz7dll9	793	8	transplant	transplant	NN
cord-023443-pvz7dll9	793	9	,	,	,
cord-023443-pvz7dll9	793	10	and	and	CC
cord-023443-pvz7dll9	793	11	the	the	DT
cord-023443-pvz7dll9	793	12	mononuclear	mononuclear	NN
cord-023443-pvz7dll9	793	13	cells	cell	NNS
cord-023443-pvz7dll9	793	14	(	(	-LRB-
cord-023443-pvz7dll9	793	15	MNCs	mnc	NNS
cord-023443-pvz7dll9	793	16	)	)	-RRB-
cord-023443-pvz7dll9	793	17	were	be	VBD
cord-023443-pvz7dll9	793	18	isolated	isolate	VBN
cord-023443-pvz7dll9	793	19	and	and	CC
cord-023443-pvz7dll9	793	20	cryopreserved	cryopreserve	VBN
cord-023443-pvz7dll9	793	21	.	.	.
cord-023443-pvz7dll9	794	1	CD8	CD8	NNP
cord-023443-pvz7dll9	794	2	þ	þ	NNP
cord-023443-pvz7dll9	794	3	T	T	NNP
cord-023443-pvz7dll9	794	4	cells	cell	NNS
cord-023443-pvz7dll9	794	5	were	be	VBD
cord-023443-pvz7dll9	794	6	isolated	isolate	VBN
cord-023443-pvz7dll9	794	7	from	from	IN
cord-023443-pvz7dll9	794	8	the	the	DT
cord-023443-pvz7dll9	794	9	MNCs	mnc	NNS
cord-023443-pvz7dll9	794	10	by	by	IN
cord-023443-pvz7dll9	794	11	use	use	NN
cord-023443-pvz7dll9	794	12	of	of	IN
cord-023443-pvz7dll9	794	13	immunomagnetic	immunomagnetic	JJ
cord-023443-pvz7dll9	794	14	beads	bead	NNS
cord-023443-pvz7dll9	794	15	or	or	CC
cord-023443-pvz7dll9	794	16	FACS	FACS	NNP
cord-023443-pvz7dll9	794	17	and	and	CC
cord-023443-pvz7dll9	794	18	analysed	analyse	VBD
cord-023443-pvz7dll9	794	19	for	for	IN
cord-023443-pvz7dll9	794	20	the	the	DT
cord-023443-pvz7dll9	794	21	presence	presence	NN
cord-023443-pvz7dll9	794	22	of	of	IN
cord-023443-pvz7dll9	794	23	clonally	clonally	RB
cord-023443-pvz7dll9	794	24	expanded	expand	VBN
cord-023443-pvz7dll9	794	25	cells	cell	NNS
cord-023443-pvz7dll9	794	26	by	by	IN
cord-023443-pvz7dll9	794	27	T	t	NN
cord-023443-pvz7dll9	794	28	-	-	HYPH
cord-023443-pvz7dll9	794	29	cell	cell	NN
cord-023443-pvz7dll9	794	30	receptor	receptor	NN
cord-023443-pvz7dll9	794	31	clonotype	clonotype	NN
cord-023443-pvz7dll9	794	32	mapping	mapping	NN
cord-023443-pvz7dll9	794	33	based	base	VBN
cord-023443-pvz7dll9	794	34	on	on	IN
cord-023443-pvz7dll9	794	35	RT	RT	NNP
cord-023443-pvz7dll9	794	36	-	-	HYPH
cord-023443-pvz7dll9	794	37	PCR	PCR	NNP
cord-023443-pvz7dll9	794	38	and	and	CC
cord-023443-pvz7dll9	794	39	denaturing	denaturing	JJ
cord-023443-pvz7dll9	794	40	gradient	gradient	NN
cord-023443-pvz7dll9	794	41	gel	gel	NN
cord-023443-pvz7dll9	794	42	electrophoresis	electrophoresis	NN
cord-023443-pvz7dll9	794	43	(	(	-LRB-
cord-023443-pvz7dll9	794	44	DGGE	DGGE	NNP
cord-023443-pvz7dll9	794	45	)	)	-RRB-
cord-023443-pvz7dll9	794	46	.	.	.
cord-023443-pvz7dll9	795	1	Using	use	VBG
cord-023443-pvz7dll9	795	2	this	this	DT
cord-023443-pvz7dll9	795	3	gel	gel	NN
cord-023443-pvz7dll9	795	4	-	-	HYPH
cord-023443-pvz7dll9	795	5	based	base	VBN
cord-023443-pvz7dll9	795	6	methodology	methodology	NN
cord-023443-pvz7dll9	795	7	,	,	,
cord-023443-pvz7dll9	795	8	clonally	clonally	NNP
cord-023443-pvz7dll9	795	9	expanded	expand	VBD
cord-023443-pvz7dll9	795	10	T	t	NN
cord-023443-pvz7dll9	795	11	cells	cell	NNS
cord-023443-pvz7dll9	795	12	were	be	VBD
cord-023443-pvz7dll9	795	13	monitored	monitor	VBN
cord-023443-pvz7dll9	795	14	after	after	IN
cord-023443-pvz7dll9	795	15	transplant	transplant	NN
cord-023443-pvz7dll9	795	16	and	and	CC
cord-023443-pvz7dll9	795	17	compared	compare	VBN
cord-023443-pvz7dll9	795	18	to	to	IN
cord-023443-pvz7dll9	795	19	the	the	DT
cord-023443-pvz7dll9	795	20	clinical	clinical	JJ
cord-023443-pvz7dll9	795	21	data	datum	NNS
cord-023443-pvz7dll9	795	22	of	of	IN
cord-023443-pvz7dll9	795	23	the	the	DT
cord-023443-pvz7dll9	795	24	patients	patient	NNS
cord-023443-pvz7dll9	795	25	.	.	.
cord-023443-pvz7dll9	796	1	The	the	DT
cord-023443-pvz7dll9	796	2	preliminary	preliminary	JJ
cord-023443-pvz7dll9	796	3	results	result	NNS
cord-023443-pvz7dll9	796	4	demonstrates	demonstrate	VBZ
cord-023443-pvz7dll9	796	5	the	the	DT
cord-023443-pvz7dll9	796	6	presence	presence	NN
cord-023443-pvz7dll9	796	7	of	of	IN
cord-023443-pvz7dll9	796	8	clonally	clonally	RB
cord-023443-pvz7dll9	796	9	expanded	expand	VBN
cord-023443-pvz7dll9	796	10	CD8	CD8	NNP
cord-023443-pvz7dll9	796	11	þ	þ	NNP
cord-023443-pvz7dll9	796	12	T	T	NNP
cord-023443-pvz7dll9	796	13	cells	cell	NNS
cord-023443-pvz7dll9	796	14	at	at	IN
cord-023443-pvz7dll9	796	15	all	all	DT
cord-023443-pvz7dll9	796	16	time	time	NN
cord-023443-pvz7dll9	796	17	points	point	NNS
cord-023443-pvz7dll9	796	18	analysed	analyse	VBN
cord-023443-pvz7dll9	796	19	.	.	.
cord-023443-pvz7dll9	797	1	Furthermore	furthermore	RB
cord-023443-pvz7dll9	797	2	,	,	,
cord-023443-pvz7dll9	797	3	a	a	DT
cord-023443-pvz7dll9	797	4	number	number	NN
cord-023443-pvz7dll9	797	5	of	of	IN
cord-023443-pvz7dll9	797	6	clonotypes	clonotype	NNS
cord-023443-pvz7dll9	797	7	persisted	persist	VBD
cord-023443-pvz7dll9	797	8	for	for	IN
cord-023443-pvz7dll9	797	9	more	more	JJR
cord-023443-pvz7dll9	797	10	than	than	IN
cord-023443-pvz7dll9	797	11	6	6	CD
cord-023443-pvz7dll9	797	12	months	month	NNS
cord-023443-pvz7dll9	797	13	,	,	,
cord-023443-pvz7dll9	797	14	and	and	CC
cord-023443-pvz7dll9	797	15	other	other	JJ
cord-023443-pvz7dll9	797	16	clonotypes	clonotype	NNS
cord-023443-pvz7dll9	797	17	emerged	emerge	VBD
cord-023443-pvz7dll9	797	18	during	during	IN
cord-023443-pvz7dll9	797	19	this	this	DT
cord-023443-pvz7dll9	797	20	period	period	NN
cord-023443-pvz7dll9	797	21	.	.	.
cord-023443-pvz7dll9	798	1	The	the	DT
cord-023443-pvz7dll9	798	2	appearance	appearance	NN
cord-023443-pvz7dll9	798	3	of	of	IN
cord-023443-pvz7dll9	798	4	newly	newly	RB
cord-023443-pvz7dll9	798	5	emerged	emerge	VBN
cord-023443-pvz7dll9	798	6	clonotypes	clonotype	NNS
cord-023443-pvz7dll9	798	7	which	which	WDT
cord-023443-pvz7dll9	798	8	coincided	coincide	VBD
cord-023443-pvz7dll9	798	9	with	with	IN
cord-023443-pvz7dll9	798	10	clinical	clinical	JJ
cord-023443-pvz7dll9	798	11	GVHD	GVHD	NNP
cord-023443-pvz7dll9	798	12	could	could	MD
cord-023443-pvz7dll9	798	13	indicate	indicate	VB
cord-023443-pvz7dll9	798	14	a	a	DT
cord-023443-pvz7dll9	798	15	role	role	NN
cord-023443-pvz7dll9	798	16	for	for	IN
cord-023443-pvz7dll9	798	17	these	these	DT
cord-023443-pvz7dll9	798	18	T	t	NN
cord-023443-pvz7dll9	798	19	cells	cell	NNS
cord-023443-pvz7dll9	798	20	in	in	IN
cord-023443-pvz7dll9	798	21	the	the	DT
cord-023443-pvz7dll9	798	22	pathogenesis	pathogenesis	NN
cord-023443-pvz7dll9	798	23	of	of	IN
cord-023443-pvz7dll9	798	24	GVHD	GVHD	NNP
cord-023443-pvz7dll9	798	25	.	.	.
cord-023443-pvz7dll9	799	1	Background	background	NN
cord-023443-pvz7dll9	799	2	:	:	:
cord-023443-pvz7dll9	800	1	Deficiency	deficiency	NN
cord-023443-pvz7dll9	800	2	of	of	IN
cord-023443-pvz7dll9	800	3	the	the	DT
cord-023443-pvz7dll9	800	4	mannan	mannan	NN
cord-023443-pvz7dll9	800	5	-	-	HYPH
cord-023443-pvz7dll9	800	6	binding	bind	VBG
cord-023443-pvz7dll9	800	7	lectin	lectin	NN
cord-023443-pvz7dll9	800	8	(	(	-LRB-
cord-023443-pvz7dll9	800	9	MBL	MBL	NNP
cord-023443-pvz7dll9	800	10	)	)	-RRB-
cord-023443-pvz7dll9	800	11	pathway	pathway	NN
cord-023443-pvz7dll9	800	12	of	of	IN
cord-023443-pvz7dll9	800	13	innate	innate	JJ
cord-023443-pvz7dll9	800	14	immunity	immunity	NN
cord-023443-pvz7dll9	800	15	leads	lead	VBZ
cord-023443-pvz7dll9	800	16	to	to	IN
cord-023443-pvz7dll9	800	17	increased	increase	VBN
cord-023443-pvz7dll9	800	18	susceptibility	susceptibility	NN
cord-023443-pvz7dll9	800	19	to	to	IN
cord-023443-pvz7dll9	800	20	infections	infection	NNS
cord-023443-pvz7dll9	800	21	.	.	.
cord-023443-pvz7dll9	801	1	In	in	IN
cord-023443-pvz7dll9	801	2	patients	patient	NNS
cord-023443-pvz7dll9	801	3	with	with	IN
cord-023443-pvz7dll9	801	4	colorectal	colorectal	JJ
cord-023443-pvz7dll9	801	5	cancer	cancer	NN
cord-023443-pvz7dll9	801	6	,	,	,
cord-023443-pvz7dll9	801	7	postoperative	postoperative	JJ
cord-023443-pvz7dll9	801	8	infection	infection	NN
cord-023443-pvz7dll9	801	9	is	be	VBZ
cord-023443-pvz7dll9	801	10	associated	associate	VBN
cord-023443-pvz7dll9	801	11	with	with	IN
cord-023443-pvz7dll9	801	12	poor	poor	JJ
cord-023443-pvz7dll9	801	13	prognosis	prognosis	NN
cord-023443-pvz7dll9	801	14	.	.	.
cord-023443-pvz7dll9	802	1	The	the	DT
cord-023443-pvz7dll9	802	2	aim	aim	NN
cord-023443-pvz7dll9	802	3	of	of	IN
cord-023443-pvz7dll9	802	4	the	the	DT
cord-023443-pvz7dll9	802	5	present	present	JJ
cord-023443-pvz7dll9	802	6	study	study	NN
cord-023443-pvz7dll9	802	7	was	be	VBD
cord-023443-pvz7dll9	802	8	to	to	TO
cord-023443-pvz7dll9	802	9	evaluate	evaluate	VB
cord-023443-pvz7dll9	802	10	(	(	-LRB-
cord-023443-pvz7dll9	802	11	1	1	LS
cord-023443-pvz7dll9	802	12	)	)	-RRB-
cord-023443-pvz7dll9	802	13	the	the	DT
cord-023443-pvz7dll9	802	14	relation	relation	NN
cord-023443-pvz7dll9	802	15	between	between	IN
cord-023443-pvz7dll9	802	16	the	the	DT
cord-023443-pvz7dll9	802	17	MBL	MBL	NNP
cord-023443-pvz7dll9	802	18	pathway	pathway	NN
cord-023443-pvz7dll9	802	19	and	and	CC
cord-023443-pvz7dll9	802	20	postoperative	postoperative	JJ
cord-023443-pvz7dll9	802	21	infectious	infectious	JJ
cord-023443-pvz7dll9	802	22	complications	complication	NNS
cord-023443-pvz7dll9	802	23	and	and	CC
cord-023443-pvz7dll9	802	24	survival	survival	NN
cord-023443-pvz7dll9	802	25	of	of	IN
cord-023443-pvz7dll9	802	26	patients	patient	NNS
cord-023443-pvz7dll9	802	27	resected	resect	VBN
cord-023443-pvz7dll9	802	28	for	for	IN
cord-023443-pvz7dll9	802	29	colorectal	colorectal	JJ
cord-023443-pvz7dll9	802	30	cancer	cancer	NN
cord-023443-pvz7dll9	802	31	and	and	CC
cord-023443-pvz7dll9	802	32	(	(	-LRB-
cord-023443-pvz7dll9	802	33	2	2	LS
cord-023443-pvz7dll9	802	34	)	)	-RRB-
cord-023443-pvz7dll9	802	35	the	the	DT
cord-023443-pvz7dll9	802	36	role	role	NN
cord-023443-pvz7dll9	802	37	of	of	IN
cord-023443-pvz7dll9	802	38	MBL	MBL	NNP
cord-023443-pvz7dll9	802	39	as	as	IN
cord-023443-pvz7dll9	802	40	acute	acute	JJ
cord-023443-pvz7dll9	802	41	phase	phase	NN
cord-023443-pvz7dll9	802	42	reactant	reactant	NN
cord-023443-pvz7dll9	802	43	compared	compare	VBN
cord-023443-pvz7dll9	802	44	to	to	IN
cord-023443-pvz7dll9	802	45	CRP	CRP	NNP
cord-023443-pvz7dll9	802	46	.	.	.
cord-023443-pvz7dll9	803	1	Methods	method	NNS
cord-023443-pvz7dll9	803	2	:	:	:
cord-023443-pvz7dll9	803	3	Preoperative	Preoperative	NNP
cord-023443-pvz7dll9	803	4	MBL	MBL	NNP
cord-023443-pvz7dll9	803	5	concentration	concentration	NN
cord-023443-pvz7dll9	803	6	,	,	,
cord-023443-pvz7dll9	803	7	MBL	MBL	NNP
cord-023443-pvz7dll9	803	8	/	/	SYM
cord-023443-pvz7dll9	803	9	MBLassociated	mblassociated	JJ
cord-023443-pvz7dll9	803	10	serine	serine	NN
cord-023443-pvz7dll9	803	11	protease	protease	NN
cord-023443-pvz7dll9	803	12	(	(	-LRB-
cord-023443-pvz7dll9	803	13	MASP	MASP	NNP
cord-023443-pvz7dll9	803	14	)	)	-RRB-
cord-023443-pvz7dll9	803	15	activity	activity	NN
cord-023443-pvz7dll9	803	16	and	and	CC
cord-023443-pvz7dll9	803	17	CRP	CRP	NNP
cord-023443-pvz7dll9	803	18	were	be	VBD
cord-023443-pvz7dll9	803	19	determined	determine	VBN
cord-023443-pvz7dll9	803	20	in	in	IN
cord-023443-pvz7dll9	803	21	serum	serum	NN
cord-023443-pvz7dll9	803	22	from	from	IN
cord-023443-pvz7dll9	803	23	611	611	CD
cord-023443-pvz7dll9	803	24	patients	patient	NNS
cord-023443-pvz7dll9	803	25	and	and	CC
cord-023443-pvz7dll9	803	26	150	150	CD
cord-023443-pvz7dll9	803	27	healthy	healthy	JJ
cord-023443-pvz7dll9	803	28	controls	control	NNS
cord-023443-pvz7dll9	803	29	.	.	.
cord-023443-pvz7dll9	804	1	The	the	DT
cord-023443-pvz7dll9	804	2	patients	patient	NNS
cord-023443-pvz7dll9	804	3	were	be	VBD
cord-023443-pvz7dll9	804	4	observed	observe	VBN
cord-023443-pvz7dll9	804	5	for	for	IN
cord-023443-pvz7dll9	804	6	8	8	CD
cord-023443-pvz7dll9	804	7	years	year	NNS
cord-023443-pvz7dll9	804	8	.	.	.
cord-023443-pvz7dll9	805	1	Postoperative	postoperative	JJ
cord-023443-pvz7dll9	805	2	infections	infection	NNS
cord-023443-pvz7dll9	805	3	,	,	,
cord-023443-pvz7dll9	805	4	recurrence	recurrence	NN
cord-023443-pvz7dll9	805	5	and	and	CC
cord-023443-pvz7dll9	805	6	survival	survival	NN
cord-023443-pvz7dll9	805	7	were	be	VBD
cord-023443-pvz7dll9	805	8	recorded	record	VBN
cord-023443-pvz7dll9	805	9	.	.	.
cord-023443-pvz7dll9	806	1	Results	result	NNS
cord-023443-pvz7dll9	806	2	:	:	:
cord-023443-pvz7dll9	807	1	The	the	DT
cord-023443-pvz7dll9	807	2	MBL	MBL	NNP
cord-023443-pvz7dll9	807	3	pathway	pathway	NN
cord-023443-pvz7dll9	807	4	components	component	NNS
cord-023443-pvz7dll9	807	5	were	be	VBD
cord-023443-pvz7dll9	807	6	increased	increase	VBN
cord-023443-pvz7dll9	807	7	in	in	IN
cord-023443-pvz7dll9	807	8	the	the	DT
cord-023443-pvz7dll9	807	9	patients	patient	NNS
cord-023443-pvz7dll9	807	10	(	(	-LRB-
cord-023443-pvz7dll9	807	11	P	p	NN
cord-023443-pvz7dll9	807	12	<	<	XX
cord-023443-pvz7dll9	807	13	0.0001	0.0001	CD
cord-023443-pvz7dll9	807	14	)	)	-RRB-
cord-023443-pvz7dll9	807	15	compared	compare	VBN
cord-023443-pvz7dll9	807	16	to	to	IN
cord-023443-pvz7dll9	807	17	healthy	healthy	JJ
cord-023443-pvz7dll9	807	18	controls	control	NNS
cord-023443-pvz7dll9	807	19	.	.	.
cord-023443-pvz7dll9	808	1	Low	low	JJ
cord-023443-pvz7dll9	808	2	MBL	MBL	NNP
cord-023443-pvz7dll9	808	3	levels	level	NNS
cord-023443-pvz7dll9	808	4	were	be	VBD
cord-023443-pvz7dll9	808	5	predictive	predictive	JJ
cord-023443-pvz7dll9	808	6	of	of	IN
cord-023443-pvz7dll9	808	7	pneumonia	pneumonia	NN
cord-023443-pvz7dll9	808	8	(	(	-LRB-
cord-023443-pvz7dll9	808	9	P	p	NN
cord-023443-pvz7dll9	808	10	¼	¼	CD
cord-023443-pvz7dll9	808	11	0.01	0.01	CD
cord-023443-pvz7dll9	808	12	)	)	-RRB-
cord-023443-pvz7dll9	808	13	,	,	,
cord-023443-pvz7dll9	808	14	and	and	CC
cord-023443-pvz7dll9	808	15	pneumonia	pneumonia	NN
cord-023443-pvz7dll9	808	16	(	(	-LRB-
cord-023443-pvz7dll9	808	17	n	n	NN
cord-023443-pvz7dll9	808	18	¼	¼	NNP
cord-023443-pvz7dll9	808	19	87	87	CD
cord-023443-pvz7dll9	808	20	)	)	-RRB-
cord-023443-pvz7dll9	808	21	was	be	VBD
cord-023443-pvz7dll9	808	22	associated	associate	VBN
cord-023443-pvz7dll9	808	23	with	with	IN
cord-023443-pvz7dll9	808	24	poor	poor	JJ
cord-023443-pvz7dll9	808	25	survival	survival	NN
cord-023443-pvz7dll9	808	26	(	(	-LRB-
cord-023443-pvz7dll9	808	27	P	p	NN
cord-023443-pvz7dll9	808	28	¼	¼	CD
cord-023443-pvz7dll9	808	29	0.003	0.003	CD
cord-023443-pvz7dll9	808	30	,	,	,
cord-023443-pvz7dll9	808	31	HR	HR	NNP
cord-023443-pvz7dll9	808	32	¼	¼	NNP
cord-023443-pvz7dll9	808	33	1.5	1.5	CD
cord-023443-pvz7dll9	808	34	,	,	,
cord-023443-pvz7dll9	808	35	95	95	CD
cord-023443-pvz7dll9	808	36	%	%	NN
cord-023443-pvz7dll9	808	37	CI	CI	NNP
cord-023443-pvz7dll9	808	38	1.1	1.1	CD
cord-023443-pvz7dll9	808	39	-	-	SYM
cord-023443-pvz7dll9	808	40	1.9	1.9	CD
cord-023443-pvz7dll9	808	41	)	)	-RRB-
cord-023443-pvz7dll9	808	42	.	.	.
cord-023443-pvz7dll9	809	1	MBL	MBL	NNP
cord-023443-pvz7dll9	809	2	and	and	CC
cord-023443-pvz7dll9	809	3	MBL/	MBL/	NNP
cord-023443-pvz7dll9	809	4	MASP	MASP	NNP
cord-023443-pvz7dll9	809	5	activity	activity	NN
cord-023443-pvz7dll9	809	6	could	could	MD
cord-023443-pvz7dll9	809	7	not	not	RB
cord-023443-pvz7dll9	809	8	predict	predict	VB
cord-023443-pvz7dll9	809	9	postoperative	postoperative	JJ
cord-023443-pvz7dll9	809	10	overall	overall	JJ
cord-023443-pvz7dll9	809	11	infections	infection	NNS
cord-023443-pvz7dll9	809	12	.	.	.
cord-023443-pvz7dll9	810	1	MBL	MBL	NNP
cord-023443-pvz7dll9	810	2	showed	show	VBD
cord-023443-pvz7dll9	810	3	no	no	DT
cord-023443-pvz7dll9	810	4	correlation	correlation	NN
cord-023443-pvz7dll9	810	5	(	(	-LRB-
cord-023443-pvz7dll9	810	6	spearman	spearman	NNP
cord-023443-pvz7dll9	810	7	's	's	POS
cord-023443-pvz7dll9	810	8	r	r	NNP
cord-023443-pvz7dll9	810	9	¼	¼	NNP
cord-023443-pvz7dll9	810	10	0.02	0.02	CD
cord-023443-pvz7dll9	810	11	,	,	,
cord-023443-pvz7dll9	810	12	95	95	CD
cord-023443-pvz7dll9	810	13	%	%	NN
cord-023443-pvz7dll9	811	1	CI	CI	NNP
cord-023443-pvz7dll9	811	2	À0.06	À0.06	NNP
cord-023443-pvz7dll9	811	3	-	-	HYPH
cord-023443-pvz7dll9	811	4	0.10	0.10	CD
cord-023443-pvz7dll9	811	5	)	)	-RRB-
cord-023443-pvz7dll9	811	6	with	with	IN
cord-023443-pvz7dll9	811	7	CRP	CRP	NNP
cord-023443-pvz7dll9	811	8	.	.	.
cord-023443-pvz7dll9	812	1	Conclusions	conclusion	NNS
cord-023443-pvz7dll9	812	2	:	:	:
cord-023443-pvz7dll9	813	1	Low	low	JJ
cord-023443-pvz7dll9	813	2	preoperative	preoperative	JJ
cord-023443-pvz7dll9	813	3	MBL	MBL	NNP
cord-023443-pvz7dll9	813	4	levels	level	NNS
cord-023443-pvz7dll9	813	5	are	be	VBP
cord-023443-pvz7dll9	813	6	predictive	predictive	JJ
cord-023443-pvz7dll9	813	7	of	of	IN
cord-023443-pvz7dll9	813	8	pneumonia	pneumonia	NN
cord-023443-pvz7dll9	813	9	,	,	,
cord-023443-pvz7dll9	813	10	which	which	WDT
cord-023443-pvz7dll9	813	11	is	be	VBZ
cord-023443-pvz7dll9	813	12	associated	associate	VBN
cord-023443-pvz7dll9	813	13	with	with	IN
cord-023443-pvz7dll9	813	14	poorer	poor	JJR
cord-023443-pvz7dll9	813	15	survival	survival	NN
cord-023443-pvz7dll9	813	16	.	.	.
cord-023443-pvz7dll9	814	1	MBL	MBL	NNP
cord-023443-pvz7dll9	814	2	concentration	concentration	NN
cord-023443-pvz7dll9	814	3	and	and	CC
cord-023443-pvz7dll9	814	4	MBL	MBL	NNP
cord-023443-pvz7dll9	814	5	/	/	SYM
cord-023443-pvz7dll9	814	6	MASP	MASP	NNP
cord-023443-pvz7dll9	814	7	activity	activity	NN
cord-023443-pvz7dll9	814	8	was	be	VBD
cord-023443-pvz7dll9	814	9	not	not	RB
cord-023443-pvz7dll9	814	10	predictive	predictive	JJ
cord-023443-pvz7dll9	814	11	of	of	IN
cord-023443-pvz7dll9	814	12	other	other	JJ
cord-023443-pvz7dll9	814	13	postoperative	postoperative	JJ
cord-023443-pvz7dll9	814	14	infections	infection	NNS
cord-023443-pvz7dll9	814	15	or	or	CC
cord-023443-pvz7dll9	814	16	long	long	JJ
cord-023443-pvz7dll9	814	17	-	-	HYPH
cord-023443-pvz7dll9	814	18	term	term	NN
cord-023443-pvz7dll9	814	19	prognosis	prognosis	NN
cord-023443-pvz7dll9	814	20	.	.	.
cord-023443-pvz7dll9	815	1	MBL	MBL	NNP
cord-023443-pvz7dll9	815	2	apparently	apparently	RB
cord-023443-pvz7dll9	815	3	is	be	VBZ
cord-023443-pvz7dll9	815	4	not	not	RB
cord-023443-pvz7dll9	815	5	a	a	DT
cord-023443-pvz7dll9	815	6	surrogate	surrogate	JJ
cord-023443-pvz7dll9	815	7	measure	measure	NN
cord-023443-pvz7dll9	815	8	of	of	IN
cord-023443-pvz7dll9	815	9	CRP	CRP	NNP
cord-023443-pvz7dll9	815	10	.	.	.
cord-023443-pvz7dll9	816	1	Department	Department	NNP
cord-023443-pvz7dll9	816	2	of	of	IN
cord-023443-pvz7dll9	816	3	Surgery	Surgery	NNP
cord-023443-pvz7dll9	816	4	,	,	,
cord-023443-pvz7dll9	816	5	University	University	NNP
cord-023443-pvz7dll9	816	6	Hospital	Hospital	NNP
cord-023443-pvz7dll9	816	7	of	of	IN
cord-023443-pvz7dll9	816	8	Erlangen	Erlangen	NNP
cord-023443-pvz7dll9	816	9	,	,	,
cord-023443-pvz7dll9	816	10	Erlangen	Erlangen	NNP
cord-023443-pvz7dll9	816	11	,	,	,
cord-023443-pvz7dll9	816	12	Germany	Germany	NNP
cord-023443-pvz7dll9	816	13	.	.	.
cord-023443-pvz7dll9	817	1	E	e	NN
cord-023443-pvz7dll9	817	2	-	-	NN
cord-023443-pvz7dll9	817	3	mail	mail	NN
cord-023443-pvz7dll9	817	4	:	:	:
cord-023443-pvz7dll9	817	5	michael.siassi@rzmail.uni-erlangen.de	michael.siassi@rzmail.uni-erlangen.de	NNP
cord-023443-pvz7dll9	817	6	Introduction	introduction	NN
cord-023443-pvz7dll9	817	7	:	:	:
cord-023443-pvz7dll9	818	1	The	the	DT
cord-023443-pvz7dll9	818	2	human	human	JJ
cord-023443-pvz7dll9	818	3	collectins	collectin	NNS
cord-023443-pvz7dll9	818	4	,	,	,
cord-023443-pvz7dll9	818	5	mannan	mannan	NN
cord-023443-pvz7dll9	818	6	-	-	HYPH
cord-023443-pvz7dll9	818	7	binding	bind	VBG
cord-023443-pvz7dll9	818	8	lectin	lectin	NN
cord-023443-pvz7dll9	818	9	(	(	-LRB-
cord-023443-pvz7dll9	818	10	MBL	MBL	NNP
cord-023443-pvz7dll9	818	11	)	)	-RRB-
cord-023443-pvz7dll9	818	12	,	,	,
cord-023443-pvz7dll9	818	13	surfactant	surfactant	NN
cord-023443-pvz7dll9	818	14	protein	protein	NN
cord-023443-pvz7dll9	818	15	-	-	HYPH
cord-023443-pvz7dll9	818	16	A	a	NN
cord-023443-pvz7dll9	818	17	(	(	-LRB-
cord-023443-pvz7dll9	818	18	SP	SP	NNP
cord-023443-pvz7dll9	818	19	-	-	HYPH
cord-023443-pvz7dll9	818	20	A	A	NNP
cord-023443-pvz7dll9	818	21	)	)	-RRB-
cord-023443-pvz7dll9	818	22	and	and	CC
cord-023443-pvz7dll9	818	23	surfactantprotein	surfactantprotein	NNP
cord-023443-pvz7dll9	818	24	-	-	HYPH
cord-023443-pvz7dll9	818	25	D	D	NNP
cord-023443-pvz7dll9	818	26	(	(	-LRB-
cord-023443-pvz7dll9	818	27	SP	SP	NNP
cord-023443-pvz7dll9	818	28	-	-	HYPH
cord-023443-pvz7dll9	818	29	D	D	NNP
cord-023443-pvz7dll9	818	30	)	)	-RRB-
cord-023443-pvz7dll9	818	31	play	play	VBP
cord-023443-pvz7dll9	818	32	a	a	DT
cord-023443-pvz7dll9	818	33	central	central	JJ
cord-023443-pvz7dll9	818	34	role	role	NN
cord-023443-pvz7dll9	818	35	in	in	IN
cord-023443-pvz7dll9	818	36	the	the	DT
cord-023443-pvz7dll9	818	37	innate	innate	JJ
cord-023443-pvz7dll9	818	38	immune	immune	JJ
cord-023443-pvz7dll9	818	39	system	system	NN
cord-023443-pvz7dll9	818	40	.	.	.
cord-023443-pvz7dll9	819	1	Immunological	immunological	JJ
cord-023443-pvz7dll9	819	2	responses	response	NNS
cord-023443-pvz7dll9	819	3	to	to	IN
cord-023443-pvz7dll9	819	4	malignant	malignant	JJ
cord-023443-pvz7dll9	819	5	transformation	transformation	NN
cord-023443-pvz7dll9	819	6	of	of	IN
cord-023443-pvz7dll9	819	7	epithelial	epithelial	JJ
cord-023443-pvz7dll9	819	8	cells	cell	NNS
cord-023443-pvz7dll9	819	9	gained	gain	VBD
cord-023443-pvz7dll9	819	10	increasing	increase	VBG
cord-023443-pvz7dll9	819	11	interest	interest	NN
cord-023443-pvz7dll9	819	12	recently	recently	RB
cord-023443-pvz7dll9	819	13	.	.	.
cord-023443-pvz7dll9	820	1	A	a	DT
cord-023443-pvz7dll9	820	2	former	former	JJ
cord-023443-pvz7dll9	820	3	study	study	NN
cord-023443-pvz7dll9	820	4	could	could	MD
cord-023443-pvz7dll9	820	5	demonstrate	demonstrate	VB
cord-023443-pvz7dll9	820	6	binding	binding	NN
cord-023443-pvz7dll9	820	7	of	of	IN
cord-023443-pvz7dll9	820	8	MBL	mbl	NN
cord-023443-pvz7dll9	820	9	to	to	IN
cord-023443-pvz7dll9	820	10	certain	certain	JJ
cord-023443-pvz7dll9	820	11	colorectal	colorectal	JJ
cord-023443-pvz7dll9	820	12	carcinoma	carcinoma	NN
cord-023443-pvz7dll9	820	13	(	(	-LRB-
cord-023443-pvz7dll9	820	14	CRC	CRC	NNP
cord-023443-pvz7dll9	820	15	)	)	-RRB-
cord-023443-pvz7dll9	820	16	cell	cell	NN
cord-023443-pvz7dll9	820	17	lines	line	NNS
cord-023443-pvz7dll9	820	18	in	in	IN
cord-023443-pvz7dll9	820	19	vitro	vitro	FW
cord-023443-pvz7dll9	820	20	.	.	.
cord-023443-pvz7dll9	821	1	We	-PRON-	PRP
cord-023443-pvz7dll9	821	2	therefore	therefore	RB
cord-023443-pvz7dll9	821	3	examined	examine	VBD
cord-023443-pvz7dll9	821	4	the	the	DT
cord-023443-pvz7dll9	821	5	expression	expression	NN
cord-023443-pvz7dll9	821	6	of	of	IN
cord-023443-pvz7dll9	821	7	human	human	JJ
cord-023443-pvz7dll9	821	8	collectins	collectin	NNS
cord-023443-pvz7dll9	821	9	in	in	IN
cord-023443-pvz7dll9	821	10	normal	normal	JJ
cord-023443-pvz7dll9	821	11	colon	colon	NN
cord-023443-pvz7dll9	821	12	mucosa	mucosa	NN
cord-023443-pvz7dll9	821	13	and	and	CC
cord-023443-pvz7dll9	821	14	in	in	IN
cord-023443-pvz7dll9	821	15	colorectal	colorectal	JJ
cord-023443-pvz7dll9	821	16	carcinomas	carcinoma	NNS
cord-023443-pvz7dll9	821	17	.	.	.
cord-023443-pvz7dll9	822	1	Materials	material	NNS
cord-023443-pvz7dll9	822	2	and	and	CC
cord-023443-pvz7dll9	822	3	methods	method	NNS
cord-023443-pvz7dll9	822	4	:	:	:
cord-023443-pvz7dll9	822	5	Colon	colon	NN
cord-023443-pvz7dll9	822	6	samples	sample	NNS
cord-023443-pvz7dll9	822	7	from	from	IN
cord-023443-pvz7dll9	822	8	20	20	CD
cord-023443-pvz7dll9	822	9	CRC	CRC	NNP
cord-023443-pvz7dll9	822	10	patients	patient	NNS
cord-023443-pvz7dll9	822	11	and	and	CC
cord-023443-pvz7dll9	822	12	10	10	CD
cord-023443-pvz7dll9	822	13	normal	normal	JJ
cord-023443-pvz7dll9	822	14	mucosa	mucosa	JJ
cord-023443-pvz7dll9	822	15	samples	sample	NNS
cord-023443-pvz7dll9	822	16	were	be	VBD
cord-023443-pvz7dll9	822	17	collected	collect	VBN
cord-023443-pvz7dll9	822	18	immediately	immediately	RB
cord-023443-pvz7dll9	822	19	after	after	IN
cord-023443-pvz7dll9	822	20	surgery	surgery	NN
cord-023443-pvz7dll9	822	21	.	.	.
cord-023443-pvz7dll9	823	1	The	the	DT
cord-023443-pvz7dll9	823	2	tissue	tissue	NN
cord-023443-pvz7dll9	823	3	was	be	VBD
cord-023443-pvz7dll9	823	4	microdissected	microdissecte	VBN
cord-023443-pvz7dll9	823	5	and	and	CC
cord-023443-pvz7dll9	823	6	RNA	RNA	NNP
cord-023443-pvz7dll9	823	7	isolated	isolate	VBD
cord-023443-pvz7dll9	823	8	(	(	-LRB-
cord-023443-pvz7dll9	823	9	Qiagen	Qiagen	NNP
cord-023443-pvz7dll9	823	10	,	,	,
cord-023443-pvz7dll9	823	11	Rneasy	Rneasy	NNP
cord-023443-pvz7dll9	823	12	-	-	HYPH
cord-023443-pvz7dll9	823	13	Kit	Kit	NNP
cord-023443-pvz7dll9	823	14	)	)	-RRB-
cord-023443-pvz7dll9	823	15	.	.	.
cord-023443-pvz7dll9	824	1	Gene	gene	NN
cord-023443-pvz7dll9	824	2	expression	expression	NN
cord-023443-pvz7dll9	824	3	profiles	profile	NNS
cord-023443-pvz7dll9	824	4	were	be	VBD
cord-023443-pvz7dll9	824	5	analysed	analyse	VBN
cord-023443-pvz7dll9	824	6	using	use	VBG
cord-023443-pvz7dll9	824	7	Gene	gene	NN
cord-023443-pvz7dll9	824	8	-	-	HYPH
cord-023443-pvz7dll9	824	9	chips	chip	NNS
cord-023443-pvz7dll9	824	10	(	(	-LRB-
cord-023443-pvz7dll9	824	11	Affymetrix	Affymetrix	NNP
cord-023443-pvz7dll9	824	12	,	,	,
cord-023443-pvz7dll9	824	13	HG	HG	NNP
cord-023443-pvz7dll9	824	14	-	-	HYPH
cord-023443-pvz7dll9	824	15	U133	U133	NNP
cord-023443-pvz7dll9	824	16	)	)	-RRB-
cord-023443-pvz7dll9	824	17	.	.	.
cord-023443-pvz7dll9	825	1	We	-PRON-	PRP
cord-023443-pvz7dll9	825	2	analysed	analyse	VBD
cord-023443-pvz7dll9	825	3	the	the	DT
cord-023443-pvz7dll9	825	4	data	datum	NNS
cord-023443-pvz7dll9	825	5	for	for	IN
cord-023443-pvz7dll9	825	6	the	the	DT
cord-023443-pvz7dll9	825	7	expression	expression	NN
cord-023443-pvz7dll9	825	8	of	of	IN
cord-023443-pvz7dll9	825	9	MBL	MBL	NNP
cord-023443-pvz7dll9	825	10	,	,	,
cord-023443-pvz7dll9	825	11	its	-PRON-	PRP$
cord-023443-pvz7dll9	825	12	associated	associated	JJ
cord-023443-pvz7dll9	825	13	serine	serine	NN
cord-023443-pvz7dll9	825	14	proteases	protease	NNS
cord-023443-pvz7dll9	825	15	mannan	mannan	NN
cord-023443-pvz7dll9	825	16	-	-	HYPH
cord-023443-pvz7dll9	825	17	binding	bind	VBG
cord-023443-pvz7dll9	825	18	lectinassociated	lectinassociated	JJ
cord-023443-pvz7dll9	825	19	serine	serine	NN
cord-023443-pvz7dll9	825	20	protease	protease	NN
cord-023443-pvz7dll9	825	21	1/2	1/2	CD
cord-023443-pvz7dll9	825	22	(	(	-LRB-
cord-023443-pvz7dll9	825	23	MASP	MASP	NNP
cord-023443-pvz7dll9	825	24	1/2	1/2	CD
cord-023443-pvz7dll9	825	25	)	)	-RRB-
cord-023443-pvz7dll9	825	26	,	,	,
cord-023443-pvz7dll9	825	27	SP	SP	NNP
cord-023443-pvz7dll9	825	28	-	-	HYPH
cord-023443-pvz7dll9	825	29	A	A	NNP
cord-023443-pvz7dll9	825	30	and	and	CC
cord-023443-pvz7dll9	825	31	SP	SP	NNP
cord-023443-pvz7dll9	825	32	-	-	HYPH
cord-023443-pvz7dll9	825	33	D.	D.	NNP
cord-023443-pvz7dll9	826	1	The	the	DT
cord-023443-pvz7dll9	826	2	signal	signal	JJ
cord-023443-pvz7dll9	826	3	intensity	intensity	NN
cord-023443-pvz7dll9	826	4	of	of	IN
cord-023443-pvz7dll9	826	5	the	the	DT
cord-023443-pvz7dll9	826	6	genes	gene	NNS
cord-023443-pvz7dll9	826	7	of	of	IN
cord-023443-pvz7dll9	826	8	interest	interest	NN
cord-023443-pvz7dll9	826	9	was	be	VBD
cord-023443-pvz7dll9	826	10	compared	compare	VBN
cord-023443-pvz7dll9	826	11	using	use	VBG
cord-023443-pvz7dll9	826	12	the	the	DT
cord-023443-pvz7dll9	826	13	Mann	Mann	NNP
cord-023443-pvz7dll9	826	14	-	-	HYPH
cord-023443-pvz7dll9	826	15	Whitney	Whitney	NNP
cord-023443-pvz7dll9	826	16	U	U	NNP
cord-023443-pvz7dll9	826	17	-	-	HYPH
cord-023443-pvz7dll9	826	18	test	test	NN
cord-023443-pvz7dll9	826	19	.	.	.
cord-023443-pvz7dll9	827	1	Results	result	NNS
cord-023443-pvz7dll9	827	2	:	:	:
cord-023443-pvz7dll9	828	1	The	the	DT
cord-023443-pvz7dll9	828	2	expression	expression	NN
cord-023443-pvz7dll9	828	3	of	of	IN
cord-023443-pvz7dll9	828	4	human	human	JJ
cord-023443-pvz7dll9	828	5	collectins	collectin	NNS
cord-023443-pvz7dll9	828	6	in	in	IN
cord-023443-pvz7dll9	828	7	normal	normal	JJ
cord-023443-pvz7dll9	828	8	human	human	JJ
cord-023443-pvz7dll9	828	9	colon	colon	NN
cord-023443-pvz7dll9	828	10	mucosa	mucosa	NN
cord-023443-pvz7dll9	828	11	was	be	VBD
cord-023443-pvz7dll9	828	12	generally	generally	RB
cord-023443-pvz7dll9	828	13	low	low	JJ
cord-023443-pvz7dll9	828	14	.	.	.
cord-023443-pvz7dll9	829	1	Only	only	RB
cord-023443-pvz7dll9	829	2	the	the	DT
cord-023443-pvz7dll9	829	3	expression	expression	NN
cord-023443-pvz7dll9	829	4	of	of	IN
cord-023443-pvz7dll9	829	5	SP	SP	NNP
cord-023443-pvz7dll9	829	6	-	-	HYPH
cord-023443-pvz7dll9	829	7	A	A	NNP
cord-023443-pvz7dll9	829	8	and	and	CC
cord-023443-pvz7dll9	829	9	MASP-2	MASP-2	NNP
cord-023443-pvz7dll9	829	10	reached	reach	VBD
cord-023443-pvz7dll9	829	11	the	the	DT
cord-023443-pvz7dll9	829	12	noise	noise	NN
cord-023443-pvz7dll9	829	13	threshold	threshold	NN
cord-023443-pvz7dll9	829	14	of	of	IN
cord-023443-pvz7dll9	829	15	250	250	CD
cord-023443-pvz7dll9	829	16	signals	signal	NNS
cord-023443-pvz7dll9	829	17	.	.	.
cord-023443-pvz7dll9	830	1	These	these	DT
cord-023443-pvz7dll9	830	2	genes	gene	NNS
cord-023443-pvz7dll9	830	3	were	be	VBD
cord-023443-pvz7dll9	830	4	significantly	significantly	RB
cord-023443-pvz7dll9	830	5	downregulated	downregulate	VBN
cord-023443-pvz7dll9	830	6	in	in	IN
cord-023443-pvz7dll9	830	7	CRC	CRC	NNP
cord-023443-pvz7dll9	830	8	specimens	specimen	NNS
cord-023443-pvz7dll9	830	9	.	.	.
cord-023443-pvz7dll9	831	1	The	the	DT
cord-023443-pvz7dll9	831	2	expression	expression	NN
cord-023443-pvz7dll9	831	3	of	of	IN
cord-023443-pvz7dll9	831	4	the	the	DT
cord-023443-pvz7dll9	831	5	other	other	JJ
cord-023443-pvz7dll9	831	6	proteins	protein	NNS
cord-023443-pvz7dll9	831	7	showed	show	VBD
cord-023443-pvz7dll9	831	8	no	no	DT
cord-023443-pvz7dll9	831	9	difference	difference	NN
cord-023443-pvz7dll9	831	10	in	in	IN
cord-023443-pvz7dll9	831	11	normal	normal	JJ
cord-023443-pvz7dll9	831	12	mucosa	mucosa	NN
cord-023443-pvz7dll9	831	13	and	and	CC
cord-023443-pvz7dll9	831	14	CRC	CRC	NNP
cord-023443-pvz7dll9	831	15	.	.	.
cord-023443-pvz7dll9	832	1	Conclusion	conclusion	NN
cord-023443-pvz7dll9	832	2	:	:	:
cord-023443-pvz7dll9	833	1	As	as	IN
cord-023443-pvz7dll9	833	2	demonstrated	demonstrate	VBN
cord-023443-pvz7dll9	833	3	before	before	RB
cord-023443-pvz7dll9	833	4	,	,	,
cord-023443-pvz7dll9	833	5	the	the	DT
cord-023443-pvz7dll9	833	6	expression	expression	NN
cord-023443-pvz7dll9	833	7	of	of	IN
cord-023443-pvz7dll9	833	8	human	human	JJ
cord-023443-pvz7dll9	833	9	collectins	collectin	NNS
cord-023443-pvz7dll9	833	10	in	in	IN
cord-023443-pvz7dll9	833	11	normal	normal	JJ
cord-023443-pvz7dll9	833	12	colon	colon	NN
cord-023443-pvz7dll9	833	13	was	be	VBD
cord-023443-pvz7dll9	833	14	low	low	JJ
cord-023443-pvz7dll9	833	15	in	in	IN
cord-023443-pvz7dll9	833	16	this	this	DT
cord-023443-pvz7dll9	833	17	Being	be	VBG
cord-023443-pvz7dll9	833	18	the	the	DT
cord-023443-pvz7dll9	833	19	first	first	JJ
cord-023443-pvz7dll9	833	20	lymph	lymph	NN
cord-023443-pvz7dll9	833	21	node	node	NN
cord-023443-pvz7dll9	833	22	to	to	TO
cord-023443-pvz7dll9	833	23	receive	receive	VB
cord-023443-pvz7dll9	833	24	drainage	drainage	NN
cord-023443-pvz7dll9	833	25	from	from	IN
cord-023443-pvz7dll9	833	26	the	the	DT
cord-023443-pvz7dll9	833	27	tumour	tumour	NN
cord-023443-pvz7dll9	833	28	area	area	NN
cord-023443-pvz7dll9	833	29	,	,	,
cord-023443-pvz7dll9	833	30	the	the	DT
cord-023443-pvz7dll9	833	31	sentinel	sentinel	NN
cord-023443-pvz7dll9	833	32	node	node	NN
cord-023443-pvz7dll9	833	33	offers	offer	VBZ
cord-023443-pvz7dll9	833	34	a	a	DT
cord-023443-pvz7dll9	833	35	unique	unique	JJ
cord-023443-pvz7dll9	833	36	possibility	possibility	NN
cord-023443-pvz7dll9	833	37	to	to	TO
cord-023443-pvz7dll9	833	38	obtain	obtain	VB
cord-023443-pvz7dll9	833	39	tumour	tumour	NN
cord-023443-pvz7dll9	833	40	-	-	HYPH
cord-023443-pvz7dll9	833	41	reactive	reactive	JJ
cord-023443-pvz7dll9	833	42	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	833	43	.	.	.
cord-023443-pvz7dll9	834	1	We	-PRON-	PRP
cord-023443-pvz7dll9	834	2	investigated	investigate	VBD
cord-023443-pvz7dll9	834	3	antitumour	antitumour	JJ
cord-023443-pvz7dll9	834	4	immune	immune	JJ
cord-023443-pvz7dll9	834	5	responses	response	NNS
cord-023443-pvz7dll9	834	6	in	in	IN
cord-023443-pvz7dll9	834	7	sentinel	sentinel	JJ
cord-023443-pvz7dll9	834	8	nodes	node	NNS
cord-023443-pvz7dll9	834	9	from	from	IN
cord-023443-pvz7dll9	834	10	patients	patient	NNS
cord-023443-pvz7dll9	834	11	with	with	IN
cord-023443-pvz7dll9	834	12	bladder	bladder	NN
cord-023443-pvz7dll9	834	13	cancer	cancer	NN
cord-023443-pvz7dll9	834	14	,	,	,
cord-023443-pvz7dll9	834	15	by	by	IN
cord-023443-pvz7dll9	834	16	assaying	assay	VBG
cord-023443-pvz7dll9	834	17	tumour	tumour	NN
cord-023443-pvz7dll9	834	18	-	-	HYPH
cord-023443-pvz7dll9	834	19	specific	specific	JJ
cord-023443-pvz7dll9	834	20	proliferation	proliferation	NN
cord-023443-pvz7dll9	834	21	and	and	CC
cord-023443-pvz7dll9	834	22	TCR	TCR	NNP
cord-023443-pvz7dll9	834	23	Vb	Vb	NNP
cord-023443-pvz7dll9	834	24	repertoires	repertoire	NNS
cord-023443-pvz7dll9	834	25	.	.	.
cord-023443-pvz7dll9	835	1	During	during	IN
cord-023443-pvz7dll9	835	2	tumour	tumour	NN
cord-023443-pvz7dll9	835	3	surgery	surgery	NN
cord-023443-pvz7dll9	835	4	,	,	,
cord-023443-pvz7dll9	835	5	sentinel	sentinel	JJ
cord-023443-pvz7dll9	835	6	lymph	lymph	NN
cord-023443-pvz7dll9	835	7	nodes	node	NNS
cord-023443-pvz7dll9	835	8	were	be	VBD
cord-023443-pvz7dll9	835	9	identified	identify	VBN
cord-023443-pvz7dll9	835	10	by	by	IN
cord-023443-pvz7dll9	835	11	peritumoural	peritumoural	JJ
cord-023443-pvz7dll9	835	12	injection	injection	NN
cord-023443-pvz7dll9	835	13	of	of	IN
cord-023443-pvz7dll9	835	14	blue	blue	JJ
cord-023443-pvz7dll9	835	15	dye	dye	NN
cord-023443-pvz7dll9	835	16	.	.	.
cord-023443-pvz7dll9	836	1	Fresh	fresh	JJ
cord-023443-pvz7dll9	836	2	specimens	specimen	NNS
cord-023443-pvz7dll9	836	3	of	of	IN
cord-023443-pvz7dll9	836	4	tumour	tumour	NN
cord-023443-pvz7dll9	836	5	,	,	,
cord-023443-pvz7dll9	836	6	sentinel	sentinel	NN
cord-023443-pvz7dll9	836	7	and	and	CC
cord-023443-pvz7dll9	836	8	nonsentinel	nonsentinel	JJ
cord-023443-pvz7dll9	836	9	lymph	lymph	NN
cord-023443-pvz7dll9	836	10	nodes	node	NNS
cord-023443-pvz7dll9	836	11	were	be	VBD
cord-023443-pvz7dll9	836	12	obtained	obtain	VBN
cord-023443-pvz7dll9	836	13	,	,	,
cord-023443-pvz7dll9	836	14	and	and	CC
cord-023443-pvz7dll9	836	15	single	single	JJ
cord-023443-pvz7dll9	836	16	-	-	HYPH
cord-023443-pvz7dll9	836	17	cell	cell	NN
cord-023443-pvz7dll9	836	18	suspensions	suspension	NNS
cord-023443-pvz7dll9	836	19	were	be	VBD
cord-023443-pvz7dll9	836	20	prepared	prepare	VBN
cord-023443-pvz7dll9	836	21	.	.	.
cord-023443-pvz7dll9	837	1	Cells	cell	NNS
cord-023443-pvz7dll9	837	2	were	be	VBD
cord-023443-pvz7dll9	837	3	assayed	assay	VBN
cord-023443-pvz7dll9	837	4	for	for	IN
cord-023443-pvz7dll9	837	5	reactivity	reactivity	NN
cord-023443-pvz7dll9	837	6	against	against	IN
cord-023443-pvz7dll9	837	7	autologous	autologous	JJ
cord-023443-pvz7dll9	837	8	tumour	tumour	NN
cord-023443-pvz7dll9	837	9	extract	extract	NN
cord-023443-pvz7dll9	837	10	in	in	IN
cord-023443-pvz7dll9	837	11	[	[	-LRB-
cord-023443-pvz7dll9	837	12	3	3	CD
cord-023443-pvz7dll9	837	13	H]-thymidine	H]-thymidine	NNP
cord-023443-pvz7dll9	837	14	incorporation	incorporation	NN
cord-023443-pvz7dll9	837	15	assays	assay	NNS
cord-023443-pvz7dll9	837	16	and	and	CC
cord-023443-pvz7dll9	837	17	characterized	characterize	VBN
cord-023443-pvz7dll9	837	18	by	by	IN
cord-023443-pvz7dll9	837	19	flow	flow	NN
cord-023443-pvz7dll9	837	20	cytometry	cytometry	NN
cord-023443-pvz7dll9	837	21	.	.	.
cord-023443-pvz7dll9	838	1	Parallel	parallel	JJ
cord-023443-pvz7dll9	838	2	analyses	analysis	NNS
cord-023443-pvz7dll9	838	3	of	of	IN
cord-023443-pvz7dll9	838	4	the	the	DT
cord-023443-pvz7dll9	838	5	expression	expression	NN
cord-023443-pvz7dll9	838	6	of	of	IN
cord-023443-pvz7dll9	838	7	Vb	Vb	NNP
cord-023443-pvz7dll9	838	8	gene	gene	NN
cord-023443-pvz7dll9	838	9	families	family	NNS
cord-023443-pvz7dll9	838	10	were	be	VBD
cord-023443-pvz7dll9	838	11	performed	perform	VBN
cord-023443-pvz7dll9	838	12	with	with	IN
cord-023443-pvz7dll9	838	13	padlock	padlock	NN
cord-023443-pvz7dll9	838	14	probes	probe	NNS
cord-023443-pvz7dll9	838	15	,	,	,
cord-023443-pvz7dll9	838	16	linear	linear	JJ
cord-023443-pvz7dll9	838	17	oligonucleotides	oligonucleotide	NNS
cord-023443-pvz7dll9	838	18	which	which	WDT
cord-023443-pvz7dll9	838	19	upon	upon	IN
cord-023443-pvz7dll9	838	20	target	target	NN
cord-023443-pvz7dll9	838	21	recognition	recognition	NN
cord-023443-pvz7dll9	838	22	can	can	MD
cord-023443-pvz7dll9	838	23	be	be	VB
cord-023443-pvz7dll9	838	24	converted	convert	VBN
cord-023443-pvz7dll9	838	25	to	to	IN
cord-023443-pvz7dll9	838	26	circular	circular	JJ
cord-023443-pvz7dll9	838	27	molecules	molecule	NNS
cord-023443-pvz7dll9	838	28	by	by	IN
cord-023443-pvz7dll9	838	29	a	a	DT
cord-023443-pvz7dll9	838	30	ligase	ligase	NN
cord-023443-pvz7dll9	838	31	.	.	.
cord-023443-pvz7dll9	839	1	Probes	probe	NNS
cord-023443-pvz7dll9	839	2	were	be	VBD
cord-023443-pvz7dll9	839	3	reacted	react	VBN
cord-023443-pvz7dll9	839	4	with	with	IN
cord-023443-pvz7dll9	839	5	cDNA	cdna	NN
cord-023443-pvz7dll9	839	6	prepared	prepare	VBN
cord-023443-pvz7dll9	839	7	from	from	IN
cord-023443-pvz7dll9	839	8	magnetically	magnetically	RB
cord-023443-pvz7dll9	839	9	separated	separate	VBN
cord-023443-pvz7dll9	839	10	CD4	CD4	NNP
cord-023443-pvz7dll9	839	11	þ	þ	NNP
cord-023443-pvz7dll9	839	12	cells	cell	NNS
cord-023443-pvz7dll9	839	13	,	,	,
cord-023443-pvz7dll9	839	14	and	and	CC
cord-023443-pvz7dll9	839	15	the	the	DT
cord-023443-pvz7dll9	839	16	TCR	TCR	NNP
cord-023443-pvz7dll9	839	17	repertoire	repertoire	NN
cord-023443-pvz7dll9	839	18	was	be	VBD
cord-023443-pvz7dll9	839	19	determined	determine	VBN
cord-023443-pvz7dll9	839	20	by	by	IN
cord-023443-pvz7dll9	839	21	hybridizing	hybridize	VBG
cord-023443-pvz7dll9	839	22	the	the	DT
cord-023443-pvz7dll9	839	23	products	product	NNS
cord-023443-pvz7dll9	839	24	to	to	IN
cord-023443-pvz7dll9	839	25	oligonucleotide	oligonucleotide	JJ
cord-023443-pvz7dll9	839	26	microarrays	microarray	NNS
cord-023443-pvz7dll9	839	27	.	.	.
cord-023443-pvz7dll9	840	1	Dose	dose	NN
cord-023443-pvz7dll9	840	2	-	-	HYPH
cord-023443-pvz7dll9	840	3	dependent	dependent	JJ
cord-023443-pvz7dll9	840	4	proliferation	proliferation	NN
cord-023443-pvz7dll9	840	5	in	in	IN
cord-023443-pvz7dll9	840	6	response	response	NN
cord-023443-pvz7dll9	840	7	to	to	TO
cord-023443-pvz7dll9	840	8	tumour	tumour	NN
cord-023443-pvz7dll9	840	9	extract	extract	NN
cord-023443-pvz7dll9	840	10	could	could	MD
cord-023443-pvz7dll9	840	11	be	be	VB
cord-023443-pvz7dll9	840	12	detected	detect	VBN
cord-023443-pvz7dll9	840	13	in	in	IN
cord-023443-pvz7dll9	840	14	sentinel	sentinel	JJ
cord-023443-pvz7dll9	840	15	lymph	lymph	NN
cord-023443-pvz7dll9	840	16	nodes	node	NNS
cord-023443-pvz7dll9	840	17	.	.	.
cord-023443-pvz7dll9	841	1	Common	common	JJ
cord-023443-pvz7dll9	841	2	clonal	clonal	JJ
cord-023443-pvz7dll9	841	3	expansions	expansion	NNS
cord-023443-pvz7dll9	841	4	were	be	VBD
cord-023443-pvz7dll9	841	5	detected	detect	VBN
cord-023443-pvz7dll9	841	6	among	among	IN
cord-023443-pvz7dll9	841	7	tumourinfiltrating	tumourinfiltrating	NN
cord-023443-pvz7dll9	841	8	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	841	9	and	and	CC
cord-023443-pvz7dll9	841	10	in	in	IN
cord-023443-pvz7dll9	841	11	sentinel	sentinel	JJ
cord-023443-pvz7dll9	841	12	lymph	lymph	NN
cord-023443-pvz7dll9	841	13	nodes	node	NNS
cord-023443-pvz7dll9	841	14	.	.	.
cord-023443-pvz7dll9	842	1	Nonsentinel	Nonsentinel	NNP
cord-023443-pvz7dll9	842	2	lymph	lymph	NN
cord-023443-pvz7dll9	842	3	nodes	node	NNS
cord-023443-pvz7dll9	842	4	displayed	display	VBD
cord-023443-pvz7dll9	842	5	a	a	DT
cord-023443-pvz7dll9	842	6	divergent	divergent	JJ
cord-023443-pvz7dll9	842	7	TCR	TCR	NNP
cord-023443-pvz7dll9	842	8	Vb	Vb	NNP
cord-023443-pvz7dll9	842	9	repertoire	repertoire	NN
cord-023443-pvz7dll9	842	10	.	.	.
cord-023443-pvz7dll9	843	1	These	these	DT
cord-023443-pvz7dll9	843	2	results	result	NNS
cord-023443-pvz7dll9	843	3	indicate	indicate	VBP
cord-023443-pvz7dll9	843	4	an	an	DT
cord-023443-pvz7dll9	843	5	ongoing	ongoing	JJ
cord-023443-pvz7dll9	843	6	immune	immune	JJ
cord-023443-pvz7dll9	843	7	response	response	NN
cord-023443-pvz7dll9	843	8	against	against	IN
cord-023443-pvz7dll9	843	9	tumour	tumour	NN
cord-023443-pvz7dll9	843	10	antigens	antigen	NNS
cord-023443-pvz7dll9	843	11	in	in	IN
cord-023443-pvz7dll9	843	12	sentinel	sentinel	JJ
cord-023443-pvz7dll9	843	13	nodes	node	NNS
cord-023443-pvz7dll9	843	14	,	,	,
cord-023443-pvz7dll9	843	15	draining	drain	VBG
cord-023443-pvz7dll9	843	16	urinary	urinary	JJ
cord-023443-pvz7dll9	843	17	bladder	bladder	NN
cord-023443-pvz7dll9	843	18	cancer	cancer	NN
cord-023443-pvz7dll9	843	19	.	.	.
cord-023443-pvz7dll9	844	1	Identification	identification	NN
cord-023443-pvz7dll9	844	2	of	of	IN
cord-023443-pvz7dll9	844	3	sentinel	sentinel	JJ
cord-023443-pvz7dll9	844	4	lymph	lymph	NN
cord-023443-pvz7dll9	844	5	nodes	node	NNS
cord-023443-pvz7dll9	844	6	makes	make	VBZ
cord-023443-pvz7dll9	844	7	it	-PRON-	PRP
cord-023443-pvz7dll9	844	8	possible	possible	JJ
cord-023443-pvz7dll9	844	9	to	to	TO
cord-023443-pvz7dll9	844	10	obtain	obtain	VB
cord-023443-pvz7dll9	844	11	tumour	tumour	NN
cord-023443-pvz7dll9	844	12	-	-	HYPH
cord-023443-pvz7dll9	844	13	reactive	reactive	JJ
cord-023443-pvz7dll9	844	14	lymphocytes	lymphocyte	NNS
cord-023443-pvz7dll9	844	15	for	for	IN
cord-023443-pvz7dll9	844	16	use	use	NN
cord-023443-pvz7dll9	844	17	in	in	IN
cord-023443-pvz7dll9	844	18	adoptive	adoptive	JJ
cord-023443-pvz7dll9	844	19	immunotherapy	immunotherapy	NN
cord-023443-pvz7dll9	844	20	.	.	.