id	sid	tid	token	lemma	pos
cord-347298-7kqrl3rv	1	1	key	key	NN
cord-347298-7kqrl3rv	1	2	:	:	:
cord-347298-7kqrl3rv	2	1	cord-347298	cord-347298	NNP
cord-347298-7kqrl3rv	2	2	-	-	HYPH
cord-347298-7kqrl3rv	2	3	7kqrl3rv	7kqrl3rv	CD
cord-347298-7kqrl3rv	2	4	authors	author	NNS
cord-347298-7kqrl3rv	2	5	:	:	:
cord-347298-7kqrl3rv	2	6	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	2	7	,	,	,
cord-347298-7kqrl3rv	2	8	M.P.	M.P.	NNP
cord-347298-7kqrl3rv	2	9	title	title	NN
cord-347298-7kqrl3rv	2	10	:	:	:
cord-347298-7kqrl3rv	2	11	Immunology	Immunology	NNP
cord-347298-7kqrl3rv	2	12	of	of	IN
cord-347298-7kqrl3rv	2	13	the	the	DT
cord-347298-7kqrl3rv	2	14	Testis	Testis	NNP
cord-347298-7kqrl3rv	2	15	and	and	CC
cord-347298-7kqrl3rv	2	16	Male	Male	NNP
cord-347298-7kqrl3rv	2	17	Reproductive	reproductive	JJ
cord-347298-7kqrl3rv	2	18	Tract	Tract	NNP
cord-347298-7kqrl3rv	2	19	date	date	NN
cord-347298-7kqrl3rv	2	20	:	:	:
cord-347298-7kqrl3rv	2	21	2010	2010	CD
cord-347298-7kqrl3rv	2	22	-	-	SYM
cord-347298-7kqrl3rv	2	23	07	07	CD
cord-347298-7kqrl3rv	2	24	-	-	HYPH
cord-347298-7kqrl3rv	2	25	12	12	CD
cord-347298-7kqrl3rv	2	26	journal	journal	NN
cord-347298-7kqrl3rv	2	27	:	:	:
cord-347298-7kqrl3rv	3	1	Comprehensive	Comprehensive	NNP
cord-347298-7kqrl3rv	3	2	Toxicology	Toxicology	NNP
cord-347298-7kqrl3rv	3	3	DOI	doi	NN
cord-347298-7kqrl3rv	3	4	:	:	:
cord-347298-7kqrl3rv	3	5	10.1016/	10.1016/	CD
cord-347298-7kqrl3rv	4	1	b978	b978	NNP
cord-347298-7kqrl3rv	4	2	-	-	HYPH
cord-347298-7kqrl3rv	4	3	0	0	CD
cord-347298-7kqrl3rv	4	4	-	-	HYPH
cord-347298-7kqrl3rv	4	5	08	08	CD
cord-347298-7kqrl3rv	4	6	-	-	HYPH
cord-347298-7kqrl3rv	4	7	046884	046884	CD
cord-347298-7kqrl3rv	4	8	-	-	HYPH
cord-347298-7kqrl3rv	4	9	6.01112-x	6.01112-x	CD
cord-347298-7kqrl3rv	4	10	sha	sha	NNP
cord-347298-7kqrl3rv	4	11	:	:	:
cord-347298-7kqrl3rv	5	1	78bafd0d20a38f52d407db91b5d55aeabc5b0b0a	78bafd0d20a38f52d407db91b5d55aeabc5b0b0a	RB
cord-347298-7kqrl3rv	5	2	doc_id	doc_id	CD
cord-347298-7kqrl3rv	5	3	:	:	:
cord-347298-7kqrl3rv	5	4	347298	347298	CD
cord-347298-7kqrl3rv	5	5	cord_uid	cord_uid	NNS
cord-347298-7kqrl3rv	5	6	:	:	:
cord-347298-7kqrl3rv	6	1	7kqrl3rv	7kqrl3rv	LS
cord-347298-7kqrl3rv	6	2	A	a	DT
cord-347298-7kqrl3rv	6	3	large	large	JJ
cord-347298-7kqrl3rv	6	4	body	body	NN
cord-347298-7kqrl3rv	6	5	of	of	IN
cord-347298-7kqrl3rv	6	6	evidence	evidence	NN
cord-347298-7kqrl3rv	6	7	points	point	NNS
cord-347298-7kqrl3rv	6	8	to	to	IN
cord-347298-7kqrl3rv	6	9	the	the	DT
cord-347298-7kqrl3rv	6	10	existence	existence	NN
cord-347298-7kqrl3rv	6	11	of	of	IN
cord-347298-7kqrl3rv	6	12	a	a	DT
cord-347298-7kqrl3rv	6	13	close	close	JJ
cord-347298-7kqrl3rv	6	14	,	,	,
cord-347298-7kqrl3rv	6	15	dynamic	dynamic	JJ
cord-347298-7kqrl3rv	6	16	relationship	relationship	NN
cord-347298-7kqrl3rv	6	17	between	between	IN
cord-347298-7kqrl3rv	6	18	the	the	DT
cord-347298-7kqrl3rv	6	19	immune	immune	JJ
cord-347298-7kqrl3rv	6	20	system	system	NN
cord-347298-7kqrl3rv	6	21	and	and	CC
cord-347298-7kqrl3rv	6	22	the	the	DT
cord-347298-7kqrl3rv	6	23	male	male	JJ
cord-347298-7kqrl3rv	6	24	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	6	25	tract	tract	NN
cord-347298-7kqrl3rv	6	26	,	,	,
cord-347298-7kqrl3rv	6	27	which	which	WDT
cord-347298-7kqrl3rv	6	28	has	have	VBZ
cord-347298-7kqrl3rv	6	29	important	important	JJ
cord-347298-7kqrl3rv	6	30	implications	implication	NNS
cord-347298-7kqrl3rv	6	31	for	for	IN
cord-347298-7kqrl3rv	6	32	our	-PRON-	PRP$
cord-347298-7kqrl3rv	6	33	understanding	understanding	NN
cord-347298-7kqrl3rv	6	34	of	of	IN
cord-347298-7kqrl3rv	6	35	both	both	DT
cord-347298-7kqrl3rv	6	36	systems	system	NNS
cord-347298-7kqrl3rv	6	37	.	.	.
cord-347298-7kqrl3rv	7	1	The	the	DT
cord-347298-7kqrl3rv	7	2	testis	testis	NN
cord-347298-7kqrl3rv	7	3	and	and	CC
cord-347298-7kqrl3rv	7	4	the	the	DT
cord-347298-7kqrl3rv	7	5	male	male	JJ
cord-347298-7kqrl3rv	7	6	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	7	7	tract	tract	NN
cord-347298-7kqrl3rv	7	8	provide	provide	VBP
cord-347298-7kqrl3rv	7	9	an	an	DT
cord-347298-7kqrl3rv	7	10	environment	environment	NN
cord-347298-7kqrl3rv	7	11	that	that	WDT
cord-347298-7kqrl3rv	7	12	protects	protect	VBZ
cord-347298-7kqrl3rv	7	13	the	the	DT
cord-347298-7kqrl3rv	7	14	otherwise	otherwise	RB
cord-347298-7kqrl3rv	7	15	highly	highly	RB
cord-347298-7kqrl3rv	7	16	immunogenic	immunogenic	JJ
cord-347298-7kqrl3rv	7	17	spermatogenic	spermatogenic	JJ
cord-347298-7kqrl3rv	7	18	cells	cell	NNS
cord-347298-7kqrl3rv	7	19	and	and	CC
cord-347298-7kqrl3rv	7	20	sperm	sperm	NN
cord-347298-7kqrl3rv	7	21	from	from	IN
cord-347298-7kqrl3rv	7	22	immunological	immunological	JJ
cord-347298-7kqrl3rv	7	23	attack	attack	NN
cord-347298-7kqrl3rv	7	24	.	.	.
cord-347298-7kqrl3rv	8	1	At	at	IN
cord-347298-7kqrl3rv	8	2	the	the	DT
cord-347298-7kqrl3rv	8	3	same	same	JJ
cord-347298-7kqrl3rv	8	4	time	time	NN
cord-347298-7kqrl3rv	8	5	,	,	,
cord-347298-7kqrl3rv	8	6	secretions	secretion	NNS
cord-347298-7kqrl3rv	8	7	of	of	IN
cord-347298-7kqrl3rv	8	8	the	the	DT
cord-347298-7kqrl3rv	8	9	testis	testis	NN
cord-347298-7kqrl3rv	8	10	,	,	,
cord-347298-7kqrl3rv	8	11	including	include	VBG
cord-347298-7kqrl3rv	8	12	androgens	androgen	NNS
cord-347298-7kqrl3rv	8	13	,	,	,
cord-347298-7kqrl3rv	8	14	influence	influence	VB
cord-347298-7kqrl3rv	8	15	the	the	DT
cord-347298-7kqrl3rv	8	16	development	development	NN
cord-347298-7kqrl3rv	8	17	and	and	CC
cord-347298-7kqrl3rv	8	18	mature	mature	JJ
cord-347298-7kqrl3rv	8	19	functions	function	NNS
cord-347298-7kqrl3rv	8	20	of	of	IN
cord-347298-7kqrl3rv	8	21	the	the	DT
cord-347298-7kqrl3rv	8	22	immune	immune	JJ
cord-347298-7kqrl3rv	8	23	system	system	NN
cord-347298-7kqrl3rv	8	24	.	.	.
cord-347298-7kqrl3rv	9	1	Activation	activation	NN
cord-347298-7kqrl3rv	9	2	of	of	IN
cord-347298-7kqrl3rv	9	3	the	the	DT
cord-347298-7kqrl3rv	9	4	immune	immune	JJ
cord-347298-7kqrl3rv	9	5	system	system	NN
cord-347298-7kqrl3rv	9	6	has	have	VBZ
cord-347298-7kqrl3rv	9	7	negative	negative	JJ
cord-347298-7kqrl3rv	9	8	effects	effect	NNS
cord-347298-7kqrl3rv	9	9	on	on	IN
cord-347298-7kqrl3rv	9	10	both	both	CC
cord-347298-7kqrl3rv	9	11	androgen	androgen	NN
cord-347298-7kqrl3rv	9	12	and	and	CC
cord-347298-7kqrl3rv	9	13	sperm	sperm	NN
cord-347298-7kqrl3rv	9	14	production	production	NN
cord-347298-7kqrl3rv	9	15	,	,	,
cord-347298-7kqrl3rv	9	16	so	so	IN
cord-347298-7kqrl3rv	9	17	that	that	IN
cord-347298-7kqrl3rv	9	18	systemic	systemic	JJ
cord-347298-7kqrl3rv	9	19	or	or	CC
cord-347298-7kqrl3rv	9	20	local	local	JJ
cord-347298-7kqrl3rv	9	21	infection	infection	NN
cord-347298-7kqrl3rv	9	22	and	and	CC
cord-347298-7kqrl3rv	9	23	inflammation	inflammation	NN
cord-347298-7kqrl3rv	9	24	compromise	compromise	NN
cord-347298-7kqrl3rv	9	25	male	male	JJ
cord-347298-7kqrl3rv	9	26	fertility	fertility	NN
cord-347298-7kqrl3rv	9	27	.	.	.
cord-347298-7kqrl3rv	10	1	The	the	DT
cord-347298-7kqrl3rv	10	2	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	10	3	underlying	underlie	VBG
cord-347298-7kqrl3rv	10	4	these	these	DT
cord-347298-7kqrl3rv	10	5	interactions	interaction	NNS
cord-347298-7kqrl3rv	10	6	have	have	VBP
cord-347298-7kqrl3rv	10	7	begun	begin	VBN
cord-347298-7kqrl3rv	10	8	to	to	TO
cord-347298-7kqrl3rv	10	9	receive	receive	VB
cord-347298-7kqrl3rv	10	10	the	the	DT
cord-347298-7kqrl3rv	10	11	attention	attention	NN
cord-347298-7kqrl3rv	10	12	from	from	IN
cord-347298-7kqrl3rv	10	13	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	10	14	biologists	biologist	NNS
cord-347298-7kqrl3rv	10	15	and	and	CC
cord-347298-7kqrl3rv	10	16	immunologists	immunologist	NNS
cord-347298-7kqrl3rv	10	17	that	that	IN
cord-347298-7kqrl3rv	10	18	they	-PRON-	PRP
cord-347298-7kqrl3rv	10	19	deserve	deserve	VBP
cord-347298-7kqrl3rv	10	20	,	,	,
cord-347298-7kqrl3rv	10	21	but	but	CC
cord-347298-7kqrl3rv	10	22	many	many	JJ
cord-347298-7kqrl3rv	10	23	crucial	crucial	JJ
cord-347298-7kqrl3rv	10	24	details	detail	NNS
cord-347298-7kqrl3rv	10	25	remain	remain	VBP
cord-347298-7kqrl3rv	10	26	to	to	TO
cord-347298-7kqrl3rv	10	27	be	be	VB
cord-347298-7kqrl3rv	10	28	uncovered	uncover	VBN
cord-347298-7kqrl3rv	10	29	.	.	.
cord-347298-7kqrl3rv	11	1	A	a	DT
cord-347298-7kqrl3rv	11	2	complete	complete	JJ
cord-347298-7kqrl3rv	11	3	picture	picture	NN
cord-347298-7kqrl3rv	11	4	of	of	IN
cord-347298-7kqrl3rv	11	5	male	male	JJ
cord-347298-7kqrl3rv	11	6	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	11	7	tract	tract	NN
cord-347298-7kqrl3rv	11	8	function	function	NN
cord-347298-7kqrl3rv	11	9	and	and	CC
cord-347298-7kqrl3rv	11	10	its	-PRON-	PRP$
cord-347298-7kqrl3rv	11	11	response	response	NN
cord-347298-7kqrl3rv	11	12	to	to	IN
cord-347298-7kqrl3rv	11	13	toxic	toxic	JJ
cord-347298-7kqrl3rv	11	14	agents	agent	NNS
cord-347298-7kqrl3rv	11	15	is	be	VBZ
cord-347298-7kqrl3rv	11	16	contingent	contingent	JJ
cord-347298-7kqrl3rv	11	17	upon	upon	IN
cord-347298-7kqrl3rv	11	18	continued	continue	VBN
cord-347298-7kqrl3rv	11	19	exploration	exploration	NN
cord-347298-7kqrl3rv	11	20	of	of	IN
cord-347298-7kqrl3rv	11	21	these	these	DT
cord-347298-7kqrl3rv	11	22	interactions	interaction	NNS
cord-347298-7kqrl3rv	11	23	and	and	CC
cord-347298-7kqrl3rv	11	24	the	the	DT
cord-347298-7kqrl3rv	11	25	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	11	26	involved	involve	VBN
cord-347298-7kqrl3rv	11	27	.	.	.
cord-347298-7kqrl3rv	12	1	In	in	IN
cord-347298-7kqrl3rv	12	2	the	the	DT
cord-347298-7kqrl3rv	12	3	decade	decade	NN
cord-347298-7kqrl3rv	12	4	since	since	IN
cord-347298-7kqrl3rv	12	5	this	this	DT
cord-347298-7kqrl3rv	12	6	chapter	chapter	NN
cord-347298-7kqrl3rv	12	7	was	be	VBD
cord-347298-7kqrl3rv	12	8	first	first	RB
cord-347298-7kqrl3rv	12	9	published	publish	VBN
cord-347298-7kqrl3rv	12	10	(	(	-LRB-
cord-347298-7kqrl3rv	12	11	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	12	12	1997	1997	CD
cord-347298-7kqrl3rv	12	13	)	)	-RRB-
cord-347298-7kqrl3rv	12	14	,	,	,
cord-347298-7kqrl3rv	12	15	there	there	EX
cord-347298-7kqrl3rv	12	16	has	have	VBZ
cord-347298-7kqrl3rv	12	17	been	be	VBN
cord-347298-7kqrl3rv	12	18	considerable	considerable	JJ
cord-347298-7kqrl3rv	12	19	progress	progress	NN
cord-347298-7kqrl3rv	12	20	in	in	IN
cord-347298-7kqrl3rv	12	21	the	the	DT
cord-347298-7kqrl3rv	12	22	understanding	understanding	NN
cord-347298-7kqrl3rv	12	23	of	of	IN
cord-347298-7kqrl3rv	12	24	the	the	DT
cord-347298-7kqrl3rv	12	25	regulation	regulation	NN
cord-347298-7kqrl3rv	12	26	of	of	IN
cord-347298-7kqrl3rv	12	27	immunity	immunity	NN
cord-347298-7kqrl3rv	12	28	.	.	.
cord-347298-7kqrl3rv	13	1	Advances	advance	NNS
cord-347298-7kqrl3rv	13	2	such	such	JJ
cord-347298-7kqrl3rv	13	3	as	as	IN
cord-347298-7kqrl3rv	13	4	the	the	DT
cord-347298-7kqrl3rv	13	5	emergence	emergence	NN
cord-347298-7kqrl3rv	13	6	of	of	IN
cord-347298-7kqrl3rv	13	7	the	the	DT
cord-347298-7kqrl3rv	13	8	innate	innate	JJ
cord-347298-7kqrl3rv	13	9	immune	immune	JJ
cord-347298-7kqrl3rv	13	10	system	system	NN
cord-347298-7kqrl3rv	13	11	as	as	IN
cord-347298-7kqrl3rv	13	12	a	a	DT
cord-347298-7kqrl3rv	13	13	major	major	JJ
cord-347298-7kqrl3rv	13	14	theme	theme	NN
cord-347298-7kqrl3rv	13	15	in	in	IN
cord-347298-7kqrl3rv	13	16	immunity	immunity	NN
cord-347298-7kqrl3rv	13	17	following	follow	VBG
cord-347298-7kqrl3rv	13	18	the	the	DT
cord-347298-7kqrl3rv	13	19	discovery	discovery	NN
cord-347298-7kqrl3rv	13	20	of	of	IN
cord-347298-7kqrl3rv	13	21	the	the	DT
cord-347298-7kqrl3rv	13	22	toll	toll	NN
cord-347298-7kqrl3rv	13	23	-	-	HYPH
cord-347298-7kqrl3rv	13	24	like	like	JJ
cord-347298-7kqrl3rv	13	25	receptor	receptor	NN
cord-347298-7kqrl3rv	13	26	(	(	-LRB-
cord-347298-7kqrl3rv	13	27	TLR	TLR	NNP
cord-347298-7kqrl3rv	13	28	)	)	-RRB-
cord-347298-7kqrl3rv	13	29	family	family	NN
cord-347298-7kqrl3rv	13	30	(	(	-LRB-
cord-347298-7kqrl3rv	13	31	O	o	UH
cord-347298-7kqrl3rv	13	32	'	'	''
cord-347298-7kqrl3rv	13	33	Neill	Neill	NNP
cord-347298-7kqrl3rv	13	34	and	and	CC
cord-347298-7kqrl3rv	13	35	Dinarello	Dinarello	NNP
cord-347298-7kqrl3rv	13	36	2000	2000	CD
cord-347298-7kqrl3rv	13	37	)	)	-RRB-
cord-347298-7kqrl3rv	13	38	,	,	,
cord-347298-7kqrl3rv	13	39	the	the	DT
cord-347298-7kqrl3rv	13	40	formalization	formalization	NN
cord-347298-7kqrl3rv	13	41	of	of	IN
cord-347298-7kqrl3rv	13	42	multiple	multiple	JJ
cord-347298-7kqrl3rv	13	43	macrophage	macrophage	NN
cord-347298-7kqrl3rv	13	44	phenotypes	phenotype	NNS
cord-347298-7kqrl3rv	13	45	corresponding	correspond	VBG
cord-347298-7kqrl3rv	13	46	to	to	IN
cord-347298-7kqrl3rv	13	47	the	the	DT
cord-347298-7kqrl3rv	13	48	type	type	NN
cord-347298-7kqrl3rv	13	49	1	1	CD
cord-347298-7kqrl3rv	13	50	and	and	CC
cord-347298-7kqrl3rv	13	51	2	2	CD
cord-347298-7kqrl3rv	13	52	helper	helper	NN
cord-347298-7kqrl3rv	13	53	T	t	NN
cord-347298-7kqrl3rv	13	54	(	(	-LRB-
cord-347298-7kqrl3rv	13	55	Th	Th	NNP
cord-347298-7kqrl3rv	13	56	)	)	-RRB-
cord-347298-7kqrl3rv	13	57	cell	cell	NN
cord-347298-7kqrl3rv	13	58	subsets	subset	NNS
cord-347298-7kqrl3rv	13	59	(	(	-LRB-
cord-347298-7kqrl3rv	13	60	Mantovani	Mantovani	NNP
cord-347298-7kqrl3rv	13	61	et	et	NNP
cord-347298-7kqrl3rv	13	62	al	al	NNP
cord-347298-7kqrl3rv	13	63	.	.	NNP
cord-347298-7kqrl3rv	13	64	2005	2005	CD
cord-347298-7kqrl3rv	13	65	)	)	-RRB-
cord-347298-7kqrl3rv	13	66	,	,	,
cord-347298-7kqrl3rv	13	67	the	the	DT
cord-347298-7kqrl3rv	13	68	rehabilitation	rehabilitation	NN
cord-347298-7kqrl3rv	13	69	of	of	IN
cord-347298-7kqrl3rv	13	70	suppressor	suppressor	NN
cord-347298-7kqrl3rv	13	71	and	and	CC
cord-347298-7kqrl3rv	13	72	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	13	73	T	t	NN
cord-347298-7kqrl3rv	13	74	cells	cell	NNS
cord-347298-7kqrl3rv	13	75	(	(	-LRB-
cord-347298-7kqrl3rv	13	76	Piccirillo	Piccirillo	NNP
cord-347298-7kqrl3rv	13	77	and	and	CC
cord-347298-7kqrl3rv	13	78	Thornton	Thornton	NNP
cord-347298-7kqrl3rv	13	79	2004	2004	CD
cord-347298-7kqrl3rv	13	80	)	)	-RRB-
cord-347298-7kqrl3rv	13	81	,	,	,
cord-347298-7kqrl3rv	13	82	and	and	CC
cord-347298-7kqrl3rv	13	83	the	the	DT
cord-347298-7kqrl3rv	13	84	identification	identification	NN
cord-347298-7kqrl3rv	13	85	of	of	IN
cord-347298-7kqrl3rv	13	86	new	new	JJ
cord-347298-7kqrl3rv	13	87	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	13	88	subsets	subset	NNS
cord-347298-7kqrl3rv	13	89	,	,	,
cord-347298-7kqrl3rv	13	90	including	include	VBG
cord-347298-7kqrl3rv	13	91	Th3	th3	NN
cord-347298-7kqrl3rv	13	92	,	,	,
cord-347298-7kqrl3rv	13	93	Th17	Th17	NNP
cord-347298-7kqrl3rv	13	94	,	,	,
cord-347298-7kqrl3rv	13	95	and	and	CC
cord-347298-7kqrl3rv	13	96	natural	natural	JJ
cord-347298-7kqrl3rv	13	97	killer	killer	NN
cord-347298-7kqrl3rv	13	98	T	t	NN
cord-347298-7kqrl3rv	13	99	(	(	-LRB-
cord-347298-7kqrl3rv	13	100	NKT	NKT	NNP
cord-347298-7kqrl3rv	13	101	)	)	-RRB-
cord-347298-7kqrl3rv	13	102	cells	cell	NNS
cord-347298-7kqrl3rv	13	103	(	(	-LRB-
cord-347298-7kqrl3rv	13	104	Godfrey	Godfrey	NNP
cord-347298-7kqrl3rv	13	105	et	et	NNP
cord-347298-7kqrl3rv	13	106	al	al	NNP
cord-347298-7kqrl3rv	13	107	.	.	.
cord-347298-7kqrl3rv	13	108	2000	2000	CD
cord-347298-7kqrl3rv	13	109	;	;	:
cord-347298-7kqrl3rv	14	1	MacDonald	MacDonald	NNP
cord-347298-7kqrl3rv	14	2	1998	1998	CD
cord-347298-7kqrl3rv	14	3	;	;	:
cord-347298-7kqrl3rv	14	4	Romagnani	Romagnani	NNP
cord-347298-7kqrl3rv	14	5	2008	2008	CD
cord-347298-7kqrl3rv	14	6	)	)	-RRB-
cord-347298-7kqrl3rv	14	7	,	,	,
cord-347298-7kqrl3rv	14	8	also	also	RB
cord-347298-7kqrl3rv	14	9	have	have	VBP
cord-347298-7kqrl3rv	14	10	had	have	VBN
cord-347298-7kqrl3rv	14	11	considerable	considerable	JJ
cord-347298-7kqrl3rv	14	12	influence	influence	NN
cord-347298-7kqrl3rv	14	13	on	on	IN
cord-347298-7kqrl3rv	14	14	the	the	DT
cord-347298-7kqrl3rv	14	15	concept	concept	NN
cord-347298-7kqrl3rv	14	16	concerning	concern	VBG
cord-347298-7kqrl3rv	14	17	the	the	DT
cord-347298-7kqrl3rv	14	18	immunology	immunology	NN
cord-347298-7kqrl3rv	14	19	of	of	IN
cord-347298-7kqrl3rv	14	20	the	the	DT
cord-347298-7kqrl3rv	14	21	male	male	JJ
cord-347298-7kqrl3rv	14	22	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	14	23	tract	tract	NN
cord-347298-7kqrl3rv	14	24	.	.	.
cord-347298-7kqrl3rv	15	1	Nonetheless	nonetheless	RB
cord-347298-7kqrl3rv	15	2	,	,	,
cord-347298-7kqrl3rv	15	3	while	while	IN
cord-347298-7kqrl3rv	15	4	there	there	EX
cord-347298-7kqrl3rv	15	5	have	have	VBP
cord-347298-7kqrl3rv	15	6	been	be	VBN
cord-347298-7kqrl3rv	15	7	advances	advance	NNS
cord-347298-7kqrl3rv	15	8	in	in	IN
cord-347298-7kqrl3rv	15	9	our	-PRON-	PRP$
cord-347298-7kqrl3rv	15	10	understanding	understanding	NN
cord-347298-7kqrl3rv	15	11	of	of	IN
cord-347298-7kqrl3rv	15	12	the	the	DT
cord-347298-7kqrl3rv	15	13	interface	interface	NN
cord-347298-7kqrl3rv	15	14	between	between	IN
cord-347298-7kqrl3rv	15	15	the	the	DT
cord-347298-7kqrl3rv	15	16	male	male	JJ
cord-347298-7kqrl3rv	15	17	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	15	18	tract	tract	NN
cord-347298-7kqrl3rv	15	19	and	and	CC
cord-347298-7kqrl3rv	15	20	the	the	DT
cord-347298-7kqrl3rv	15	21	immune	immune	JJ
cord-347298-7kqrl3rv	15	22	system	system	NN
cord-347298-7kqrl3rv	15	23	,	,	,
cord-347298-7kqrl3rv	15	24	there	there	EX
cord-347298-7kqrl3rv	15	25	is	be	VBZ
cord-347298-7kqrl3rv	15	26	still	still	RB
cord-347298-7kqrl3rv	15	27	much	much	RB
cord-347298-7kqrl3rv	15	28	we	-PRON-	PRP
cord-347298-7kqrl3rv	15	29	simply	simply	RB
cord-347298-7kqrl3rv	15	30	do	do	VBP
cord-347298-7kqrl3rv	15	31	not	not	RB
cord-347298-7kqrl3rv	15	32	know	know	VB
cord-347298-7kqrl3rv	15	33	.	.	.
cord-347298-7kqrl3rv	16	1	The	the	DT
cord-347298-7kqrl3rv	16	2	need	need	NN
cord-347298-7kqrl3rv	16	3	to	to	TO
cord-347298-7kqrl3rv	16	4	understand	understand	VB
cord-347298-7kqrl3rv	16	5	this	this	DT
cord-347298-7kqrl3rv	16	6	interface	interface	NN
cord-347298-7kqrl3rv	16	7	and	and	CC
cord-347298-7kqrl3rv	16	8	the	the	DT
cord-347298-7kqrl3rv	16	9	potential	potential	JJ
cord-347298-7kqrl3rv	16	10	implications	implication	NNS
cord-347298-7kqrl3rv	16	11	for	for	IN
cord-347298-7kqrl3rv	16	12	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	16	13	toxicology	toxicology	NN
cord-347298-7kqrl3rv	16	14	continues	continue	VBZ
cord-347298-7kqrl3rv	16	15	to	to	TO
cord-347298-7kqrl3rv	16	16	be	be	VB
cord-347298-7kqrl3rv	16	17	just	just	RB
cord-347298-7kqrl3rv	16	18	as	as	RB
cord-347298-7kqrl3rv	16	19	important	important	JJ
cord-347298-7kqrl3rv	16	20	as	as	IN
cord-347298-7kqrl3rv	16	21	ever	ever	RB
cord-347298-7kqrl3rv	16	22	.	.	.
cord-347298-7kqrl3rv	17	1	There	there	EX
cord-347298-7kqrl3rv	17	2	is	be	VBZ
cord-347298-7kqrl3rv	17	3	no	no	DT
cord-347298-7kqrl3rv	17	4	doubt	doubt	NN
cord-347298-7kqrl3rv	17	5	that	that	IN
cord-347298-7kqrl3rv	17	6	the	the	DT
cord-347298-7kqrl3rv	17	7	testis	testis	NN
cord-347298-7kqrl3rv	17	8	and	and	CC
cord-347298-7kqrl3rv	17	9	the	the	DT
cord-347298-7kqrl3rv	17	10	male	male	JJ
cord-347298-7kqrl3rv	17	11	germ	germ	NN
cord-347298-7kqrl3rv	17	12	cells	cell	NNS
cord-347298-7kqrl3rv	17	13	in	in	IN
cord-347298-7kqrl3rv	17	14	particular	particular	JJ
cord-347298-7kqrl3rv	17	15	are	be	VBP
cord-347298-7kqrl3rv	17	16	susceptible	susceptible	JJ
cord-347298-7kqrl3rv	17	17	to	to	IN
cord-347298-7kqrl3rv	17	18	immunological	immunological	JJ
cord-347298-7kqrl3rv	17	19	damage	damage	NN
cord-347298-7kqrl3rv	17	20	.	.	.
cord-347298-7kqrl3rv	18	1	Clinically	clinically	RB
cord-347298-7kqrl3rv	18	2	significant	significant	JJ
cord-347298-7kqrl3rv	18	3	testicular	testicular	NN
cord-347298-7kqrl3rv	18	4	autoimmunity	autoimmunity	NN
cord-347298-7kqrl3rv	19	1	,	,	,
cord-347298-7kqrl3rv	19	2	most	most	RBS
cord-347298-7kqrl3rv	19	3	commonly	commonly	RB
cord-347298-7kqrl3rv	19	4	indicated	indicate	VBN
cord-347298-7kqrl3rv	19	5	by	by	IN
cord-347298-7kqrl3rv	19	6	the	the	DT
cord-347298-7kqrl3rv	19	7	presence	presence	NN
cord-347298-7kqrl3rv	19	8	of	of	IN
cord-347298-7kqrl3rv	19	9	antisperm	antisperm	NNP
cord-347298-7kqrl3rv	19	10	antibodies	antibody	NNS
cord-347298-7kqrl3rv	19	11	in	in	IN
cord-347298-7kqrl3rv	19	12	the	the	DT
cord-347298-7kqrl3rv	19	13	serum	serum	NN
cord-347298-7kqrl3rv	19	14	or	or	CC
cord-347298-7kqrl3rv	19	15	ejaculate	ejaculate	NN
cord-347298-7kqrl3rv	19	16	,	,	,
cord-347298-7kqrl3rv	19	17	is	be	VBZ
cord-347298-7kqrl3rv	19	18	implicated	implicate	VBN
cord-347298-7kqrl3rv	19	19	in	in	IN
cord-347298-7kqrl3rv	19	20	the	the	DT
cord-347298-7kqrl3rv	19	21	case	case	NN
cord-347298-7kqrl3rv	19	22	of	of	IN
cord-347298-7kqrl3rv	19	23	5	5	CD
cord-347298-7kqrl3rv	19	24	-	-	SYM
cord-347298-7kqrl3rv	19	25	12	12	CD
cord-347298-7kqrl3rv	19	26	%	%	NN
cord-347298-7kqrl3rv	19	27	of	of	IN
cord-347298-7kqrl3rv	19	28	all	all	DT
cord-347298-7kqrl3rv	19	29	male	male	JJ
cord-347298-7kqrl3rv	19	30	infertility	infertility	NN
cord-347298-7kqrl3rv	19	31	patients	patient	NNS
cord-347298-7kqrl3rv	19	32	within	within	IN
cord-347298-7kqrl3rv	19	33	the	the	DT
cord-347298-7kqrl3rv	19	34	developed	developed	JJ
cord-347298-7kqrl3rv	19	35	world	world	NN
cord-347298-7kqrl3rv	19	36	(	(	-LRB-
cord-347298-7kqrl3rv	19	37	Baker	Baker	NNP
cord-347298-7kqrl3rv	19	38	et	et	NNP
cord-347298-7kqrl3rv	19	39	al	al	NNP
cord-347298-7kqrl3rv	19	40	.	.	.
cord-347298-7kqrl3rv	19	41	1983	1983	CD
cord-347298-7kqrl3rv	19	42	;	;	:
cord-347298-7kqrl3rv	19	43	Pattinson	Pattinson	NNP
cord-347298-7kqrl3rv	19	44	and	and	CC
cord-347298-7kqrl3rv	19	45	Mortimer	Mortimer	NNP
cord-347298-7kqrl3rv	19	46	1987	1987	CD
cord-347298-7kqrl3rv	19	47	)	)	-RRB-
cord-347298-7kqrl3rv	19	48	,	,	,
cord-347298-7kqrl3rv	19	49	but	but	CC
cord-347298-7kqrl3rv	19	50	the	the	DT
cord-347298-7kqrl3rv	19	51	incidence	incidence	NN
cord-347298-7kqrl3rv	19	52	is	be	VBZ
cord-347298-7kqrl3rv	19	53	much	much	RB
cord-347298-7kqrl3rv	19	54	higher	high	JJR
cord-347298-7kqrl3rv	19	55	in	in	IN
cord-347298-7kqrl3rv	19	56	populations	population	NNS
cord-347298-7kqrl3rv	19	57	where	where	WRB
cord-347298-7kqrl3rv	19	58	access	access	NN
cord-347298-7kqrl3rv	19	59	to	to	IN
cord-347298-7kqrl3rv	19	60	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	19	61	health	health	NN
cord-347298-7kqrl3rv	19	62	care	care	NN
cord-347298-7kqrl3rv	19	63	is	be	VBZ
cord-347298-7kqrl3rv	19	64	limited	limit	VBN
cord-347298-7kqrl3rv	19	65	(	(	-LRB-
cord-347298-7kqrl3rv	19	66	Ekwere	Ekwere	NNP
cord-347298-7kqrl3rv	19	67	1995	1995	CD
cord-347298-7kqrl3rv	19	68	)	)	-RRB-
cord-347298-7kqrl3rv	19	69	.	.	.
cord-347298-7kqrl3rv	20	1	Common	common	JJ
cord-347298-7kqrl3rv	20	2	factors	factor	NNS
cord-347298-7kqrl3rv	20	3	suspected	suspect	VBN
cord-347298-7kqrl3rv	20	4	to	to	TO
cord-347298-7kqrl3rv	20	5	contribute	contribute	VB
cord-347298-7kqrl3rv	20	6	to	to	IN
cord-347298-7kqrl3rv	20	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	20	8	autoimmunity	autoimmunity	NN
cord-347298-7kqrl3rv	20	9	include	include	VBP
cord-347298-7kqrl3rv	20	10	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	20	11	tract	tract	JJ
cord-347298-7kqrl3rv	20	12	infections	infection	NNS
cord-347298-7kqrl3rv	20	13	,	,	,
cord-347298-7kqrl3rv	20	14	physical	physical	JJ
cord-347298-7kqrl3rv	20	15	trauma	trauma	NN
cord-347298-7kqrl3rv	20	16	,	,	,
cord-347298-7kqrl3rv	20	17	immune	immune	JJ
cord-347298-7kqrl3rv	20	18	system	system	NN
cord-347298-7kqrl3rv	20	19	dysfunction	dysfunction	NN
cord-347298-7kqrl3rv	20	20	,	,	,
cord-347298-7kqrl3rv	20	21	and	and	CC
cord-347298-7kqrl3rv	20	22	genetics	genetic	NNS
cord-347298-7kqrl3rv	20	23	.	.	.
cord-347298-7kqrl3rv	21	1	The	the	DT
cord-347298-7kqrl3rv	21	2	release	release	NN
cord-347298-7kqrl3rv	21	3	of	of	IN
cord-347298-7kqrl3rv	21	4	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	21	5	antigens	antigen	NNS
cord-347298-7kqrl3rv	21	6	from	from	IN
cord-347298-7kqrl3rv	21	7	the	the	DT
cord-347298-7kqrl3rv	21	8	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	21	9	tract	tract	NN
cord-347298-7kqrl3rv	21	10	following	follow	VBG
cord-347298-7kqrl3rv	21	11	vasectomy	vasectomy	NN
cord-347298-7kqrl3rv	21	12	generally	generally	RB
cord-347298-7kqrl3rv	21	13	results	result	VBZ
cord-347298-7kqrl3rv	21	14	in	in	IN
cord-347298-7kqrl3rv	21	15	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	21	16	responses	response	NNS
cord-347298-7kqrl3rv	21	17	,	,	,
cord-347298-7kqrl3rv	21	18	ranging	range	VBG
cord-347298-7kqrl3rv	21	19	in	in	IN
cord-347298-7kqrl3rv	21	20	severity	severity	NN
cord-347298-7kqrl3rv	21	21	from	from	IN
cord-347298-7kqrl3rv	21	22	sperm	sperm	NN
cord-347298-7kqrl3rv	21	23	antibodies	antibody	NNS
cord-347298-7kqrl3rv	21	24	to	to	IN
cord-347298-7kqrl3rv	21	25	orchitis	orchitis	NN
cord-347298-7kqrl3rv	21	26	,	,	,
cord-347298-7kqrl3rv	21	27	in	in	IN
cord-347298-7kqrl3rv	21	28	both	both	DT
cord-347298-7kqrl3rv	21	29	humans	human	NNS
cord-347298-7kqrl3rv	21	30	and	and	CC
cord-347298-7kqrl3rv	21	31	experimental	experimental	JJ
cord-347298-7kqrl3rv	21	32	animals	animal	NNS
cord-347298-7kqrl3rv	21	33	(	(	-LRB-
cord-347298-7kqrl3rv	21	34	Alexander	Alexander	NNP
cord-347298-7kqrl3rv	21	35	and	and	CC
cord-347298-7kqrl3rv	21	36	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	21	37	1979	1979	CD
cord-347298-7kqrl3rv	21	38	;	;	:
cord-347298-7kqrl3rv	22	1	Flickinger	Flickinger	NNP
cord-347298-7kqrl3rv	22	2	et	et	NNP
cord-347298-7kqrl3rv	22	3	al	al	NNP
cord-347298-7kqrl3rv	22	4	.	.	.
cord-347298-7kqrl3rv	23	1	1990a	1990a	CD
cord-347298-7kqrl3rv	23	2	;	;	:
cord-347298-7kqrl3rv	23	3	Kojima	Kojima	NNP
cord-347298-7kqrl3rv	23	4	and	and	CC
cord-347298-7kqrl3rv	23	5	Spencer	Spencer	NNP
cord-347298-7kqrl3rv	23	6	1983	1983	CD
cord-347298-7kqrl3rv	23	7	;	;	:
cord-347298-7kqrl3rv	23	8	Tung	Tung	NNP
cord-347298-7kqrl3rv	23	9	and	and	CC
cord-347298-7kqrl3rv	23	10	Alexander	Alexander	NNP
cord-347298-7kqrl3rv	23	11	1980	1980	CD
cord-347298-7kqrl3rv	23	12	)	)	-RRB-
cord-347298-7kqrl3rv	23	13	.	.	.
cord-347298-7kqrl3rv	24	1	The	the	DT
cord-347298-7kqrl3rv	24	2	potential	potential	NN
cord-347298-7kqrl3rv	24	3	for	for	IN
cord-347298-7kqrl3rv	24	4	spontaneous	spontaneous	JJ
cord-347298-7kqrl3rv	24	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	24	6	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	24	7	disease	disease	NN
cord-347298-7kqrl3rv	24	8	in	in	IN
cord-347298-7kqrl3rv	24	9	otherwise	otherwise	RB
cord-347298-7kqrl3rv	24	10	normal	normal	JJ
cord-347298-7kqrl3rv	24	11	men	man	NNS
cord-347298-7kqrl3rv	24	12	remains	remain	VBZ
cord-347298-7kqrl3rv	24	13	poorly	poorly	RB
cord-347298-7kqrl3rv	24	14	characterized	characterize	VBN
cord-347298-7kqrl3rv	24	15	,	,	,
cord-347298-7kqrl3rv	24	16	although	although	IN
cord-347298-7kqrl3rv	24	17	studies	study	NNS
cord-347298-7kqrl3rv	24	18	in	in	IN
cord-347298-7kqrl3rv	24	19	animals	animal	NNS
cord-347298-7kqrl3rv	24	20	clearly	clearly	RB
cord-347298-7kqrl3rv	24	21	indicate	indicate	VBP
cord-347298-7kqrl3rv	24	22	the	the	DT
cord-347298-7kqrl3rv	24	23	possibility	possibility	NN
cord-347298-7kqrl3rv	24	24	of	of	IN
cord-347298-7kqrl3rv	24	25	such	such	JJ
cord-347298-7kqrl3rv	24	26	reactions	reaction	NNS
cord-347298-7kqrl3rv	24	27	in	in	IN
cord-347298-7kqrl3rv	24	28	humans	human	NNS
cord-347298-7kqrl3rv	24	29	(	(	-LRB-
cord-347298-7kqrl3rv	24	30	Furbeth	Furbeth	NNP
cord-347298-7kqrl3rv	24	31	et	et	NNP
cord-347298-7kqrl3rv	24	32	al	al	NNP
cord-347298-7kqrl3rv	24	33	.	.	NNP
cord-347298-7kqrl3rv	24	34	1989	1989	CD
cord-347298-7kqrl3rv	24	35	;	;	:
cord-347298-7kqrl3rv	24	36	Tung	Tung	NNP
cord-347298-7kqrl3rv	24	37	et	et	NNP
cord-347298-7kqrl3rv	24	38	al	al	NNP
cord-347298-7kqrl3rv	24	39	.	.	NNP
cord-347298-7kqrl3rv	24	40	1981	1981	CD
cord-347298-7kqrl3rv	24	41	)	)	-RRB-
cord-347298-7kqrl3rv	24	42	.	.	.
cord-347298-7kqrl3rv	25	1	Complicating	complicate	VBG
cord-347298-7kqrl3rv	25	2	matters	matter	NNS
cord-347298-7kqrl3rv	25	3	is	be	VBZ
cord-347298-7kqrl3rv	25	4	the	the	DT
cord-347298-7kqrl3rv	25	5	fact	fact	NN
cord-347298-7kqrl3rv	25	6	that	that	IN
cord-347298-7kqrl3rv	25	7	the	the	DT
cord-347298-7kqrl3rv	25	8	testis	testis	NN
cord-347298-7kqrl3rv	25	9	is	be	VBZ
cord-347298-7kqrl3rv	25	10	an	an	DT
cord-347298-7kqrl3rv	25	11	immunologically	immunologically	RB
cord-347298-7kqrl3rv	25	12	privileged	privileged	JJ
cord-347298-7kqrl3rv	25	13	tissue	tissue	NN
cord-347298-7kqrl3rv	25	14	,	,	,
cord-347298-7kqrl3rv	25	15	in	in	IN
cord-347298-7kqrl3rv	25	16	the	the	DT
cord-347298-7kqrl3rv	25	17	sense	sense	NN
cord-347298-7kqrl3rv	25	18	that	that	IN
cord-347298-7kqrl3rv	25	19	foreign	foreign	JJ
cord-347298-7kqrl3rv	25	20	tissue	tissue	NN
cord-347298-7kqrl3rv	25	21	grafts	graft	NNS
cord-347298-7kqrl3rv	25	22	into	into	IN
cord-347298-7kqrl3rv	25	23	the	the	DT
cord-347298-7kqrl3rv	25	24	testes	testis	NNS
cord-347298-7kqrl3rv	25	25	of	of	IN
cord-347298-7kqrl3rv	25	26	experimental	experimental	JJ
cord-347298-7kqrl3rv	25	27	animals	animal	NNS
cord-347298-7kqrl3rv	25	28	survive	survive	VBP
cord-347298-7kqrl3rv	25	29	for	for	IN
cord-347298-7kqrl3rv	25	30	prolonged	prolonged	JJ
cord-347298-7kqrl3rv	25	31	periods	period	NNS
cord-347298-7kqrl3rv	25	32	(	(	-LRB-
cord-347298-7kqrl3rv	25	33	Barker	Barker	NNP
cord-347298-7kqrl3rv	25	34	and	and	CC
cord-347298-7kqrl3rv	25	35	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	25	36	1977	1977	CD
cord-347298-7kqrl3rv	25	37	;	;	:
cord-347298-7kqrl3rv	25	38	Head	Head	NNP
cord-347298-7kqrl3rv	25	39	et	et	NNP
cord-347298-7kqrl3rv	25	40	al	al	NNP
cord-347298-7kqrl3rv	25	41	.	.	NNP
cord-347298-7kqrl3rv	25	42	1983a	1983a	CD
cord-347298-7kqrl3rv	25	43	;	;	:
cord-347298-7kqrl3rv	25	44	Whitmore	Whitmore	NNP
cord-347298-7kqrl3rv	25	45	and	and	CC
cord-347298-7kqrl3rv	25	46	Gittes	Gittes	NNP
cord-347298-7kqrl3rv	25	47	1978	1978	CD
cord-347298-7kqrl3rv	25	48	)	)	-RRB-
cord-347298-7kqrl3rv	25	49	.	.	.
cord-347298-7kqrl3rv	26	1	This	this	DT
cord-347298-7kqrl3rv	26	2	dichotomy	dichotomy	NN
cord-347298-7kqrl3rv	26	3	between	between	IN
cord-347298-7kqrl3rv	26	4	immune	immune	JJ
cord-347298-7kqrl3rv	26	5	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	26	6	and	and	CC
cord-347298-7kqrl3rv	26	7	privilege	privilege	NN
cord-347298-7kqrl3rv	26	8	is	be	VBZ
cord-347298-7kqrl3rv	26	9	indicative	indicative	JJ
cord-347298-7kqrl3rv	26	10	of	of	IN
cord-347298-7kqrl3rv	26	11	a	a	DT
cord-347298-7kqrl3rv	26	12	highly	highly	RB
cord-347298-7kqrl3rv	26	13	specialized	specialized	JJ
cord-347298-7kqrl3rv	26	14	interaction	interaction	NN
cord-347298-7kqrl3rv	26	15	between	between	IN
cord-347298-7kqrl3rv	26	16	the	the	DT
cord-347298-7kqrl3rv	26	17	male	male	JJ
cord-347298-7kqrl3rv	26	18	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	26	19	system	system	NN
cord-347298-7kqrl3rv	26	20	and	and	CC
cord-347298-7kqrl3rv	26	21	the	the	DT
cord-347298-7kqrl3rv	26	22	immune	immune	JJ
cord-347298-7kqrl3rv	26	23	system	system	NN
cord-347298-7kqrl3rv	26	24	,	,	,
cord-347298-7kqrl3rv	26	25	with	with	IN
cord-347298-7kqrl3rv	26	26	potentially	potentially	RB
cord-347298-7kqrl3rv	26	27	important	important	JJ
cord-347298-7kqrl3rv	26	28	implications	implication	NNS
cord-347298-7kqrl3rv	26	29	for	for	IN
cord-347298-7kqrl3rv	26	30	both	both	DT
cord-347298-7kqrl3rv	26	31	systems	system	NNS
cord-347298-7kqrl3rv	26	32	.	.	.
cord-347298-7kqrl3rv	27	1	The	the	DT
cord-347298-7kqrl3rv	27	2	objective	objective	NN
cord-347298-7kqrl3rv	27	3	of	of	IN
cord-347298-7kqrl3rv	27	4	this	this	DT
cord-347298-7kqrl3rv	27	5	chapter	chapter	NN
cord-347298-7kqrl3rv	27	6	is	be	VBZ
cord-347298-7kqrl3rv	27	7	to	to	TO
cord-347298-7kqrl3rv	27	8	provide	provide	VB
cord-347298-7kqrl3rv	27	9	an	an	DT
cord-347298-7kqrl3rv	27	10	overview	overview	NN
cord-347298-7kqrl3rv	27	11	of	of	IN
cord-347298-7kqrl3rv	27	12	the	the	DT
cord-347298-7kqrl3rv	27	13	current	current	JJ
cord-347298-7kqrl3rv	27	14	state	state	NN
cord-347298-7kqrl3rv	27	15	of	of	IN
cord-347298-7kqrl3rv	27	16	knowledge	knowledge	NN
cord-347298-7kqrl3rv	27	17	and	and	CC
cord-347298-7kqrl3rv	27	18	to	to	TO
cord-347298-7kqrl3rv	27	19	highlight	highlight	VB
cord-347298-7kqrl3rv	27	20	issues	issue	NNS
cord-347298-7kqrl3rv	27	21	for	for	IN
cord-347298-7kqrl3rv	27	22	further	further	JJ
cord-347298-7kqrl3rv	27	23	consideration	consideration	NN
cord-347298-7kqrl3rv	27	24	that	that	WDT
cord-347298-7kqrl3rv	27	25	may	may	MD
cord-347298-7kqrl3rv	27	26	be	be	VB
cord-347298-7kqrl3rv	27	27	of	of	IN
cord-347298-7kqrl3rv	27	28	relevance	relevance	NN
cord-347298-7kqrl3rv	27	29	to	to	IN
cord-347298-7kqrl3rv	27	30	male	male	JJ
cord-347298-7kqrl3rv	27	31	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	27	32	toxicology	toxicology	NN
cord-347298-7kqrl3rv	27	33	.	.	.
cord-347298-7kqrl3rv	28	1	11.10.2	11.10.2	CD
cord-347298-7kqrl3rv	29	1	The	the	DT
cord-347298-7kqrl3rv	29	2	Interface	Interface	NNP
cord-347298-7kqrl3rv	29	3	between	between	IN
cord-347298-7kqrl3rv	29	4	the	the	DT
cord-347298-7kqrl3rv	29	5	Immune	Immune	NNP
cord-347298-7kqrl3rv	29	6	System	System	NNP
cord-347298-7kqrl3rv	29	7	and	and	CC
cord-347298-7kqrl3rv	29	8	the	the	DT
cord-347298-7kqrl3rv	29	9	Reproductive	reproductive	JJ
cord-347298-7kqrl3rv	29	10	Tract	tract	NN
cord-347298-7kqrl3rv	29	11	The	the	DT
cord-347298-7kqrl3rv	29	12	immune	immune	JJ
cord-347298-7kqrl3rv	29	13	system	system	NN
cord-347298-7kqrl3rv	29	14	is	be	VBZ
cord-347298-7kqrl3rv	29	15	the	the	DT
cord-347298-7kqrl3rv	29	16	body	body	NN
cord-347298-7kqrl3rv	29	17	's	's	POS
cord-347298-7kqrl3rv	29	18	protective	protective	JJ
cord-347298-7kqrl3rv	29	19	arsenal	arsenal	NN
cord-347298-7kqrl3rv	29	20	against	against	IN
cord-347298-7kqrl3rv	29	21	disease	disease	NN
cord-347298-7kqrl3rv	29	22	.	.	.
cord-347298-7kqrl3rv	30	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	30	2	operates	operate	VBZ
cord-347298-7kqrl3rv	30	3	via	via	IN
cord-347298-7kqrl3rv	30	4	the	the	DT
cord-347298-7kqrl3rv	30	5	detection	detection	NN
cord-347298-7kqrl3rv	30	6	of	of	IN
cord-347298-7kqrl3rv	30	7	potential	potential	JJ
cord-347298-7kqrl3rv	30	8	aggressors	aggressor	NNS
cord-347298-7kqrl3rv	30	9	,	,	,
cord-347298-7kqrl3rv	30	10	recognized	recognize	VBN
cord-347298-7kqrl3rv	30	11	through	through	IN
cord-347298-7kqrl3rv	30	12	conserved	conserve	VBN
cord-347298-7kqrl3rv	30	13	motifs	motif	NNS
cord-347298-7kqrl3rv	30	14	found	find	VBN
cord-347298-7kqrl3rv	30	15	on	on	IN
cord-347298-7kqrl3rv	30	16	pathogenic	pathogenic	JJ
cord-347298-7kqrl3rv	30	17	organisms	organism	NNS
cord-347298-7kqrl3rv	30	18	(	(	-LRB-
cord-347298-7kqrl3rv	30	19	innate	innate	JJ
cord-347298-7kqrl3rv	30	20	immunity	immunity	NN
cord-347298-7kqrl3rv	30	21	)	)	-RRB-
cord-347298-7kqrl3rv	30	22	or	or	CC
cord-347298-7kqrl3rv	30	23	confrontation	confrontation	NN
cord-347298-7kqrl3rv	30	24	by	by	IN
cord-347298-7kqrl3rv	30	25	completely	completely	RB
cord-347298-7kqrl3rv	30	26	novel	novel	JJ
cord-347298-7kqrl3rv	30	27	(	(	-LRB-
cord-347298-7kqrl3rv	30	28	i.e.	i.e.	FW
cord-347298-7kqrl3rv	30	29	,	,	,
cord-347298-7kqrl3rv	30	30	foreign	foreign	JJ
cord-347298-7kqrl3rv	30	31	)	)	-RRB-
cord-347298-7kqrl3rv	30	32	molecular	molecular	JJ
cord-347298-7kqrl3rv	30	33	structures	structure	NNS
cord-347298-7kqrl3rv	30	34	(	(	-LRB-
cord-347298-7kqrl3rv	30	35	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	30	36	immunity	immunity	NN
cord-347298-7kqrl3rv	30	37	)	)	-RRB-
cord-347298-7kqrl3rv	30	38	(	(	-LRB-
cord-347298-7kqrl3rv	30	39	Vivier	Vivier	NNPS
cord-347298-7kqrl3rv	30	40	and	and	CC
cord-347298-7kqrl3rv	30	41	Malissen	Malissen	NNP
cord-347298-7kqrl3rv	30	42	2005	2005	CD
cord-347298-7kqrl3rv	30	43	;	;	:
cord-347298-7kqrl3rv	30	44	Zinkernagel	Zinkernagel	NNP
cord-347298-7kqrl3rv	30	45	2000	2000	CD
cord-347298-7kqrl3rv	30	46	)	)	-RRB-
cord-347298-7kqrl3rv	30	47	.	.	.
cord-347298-7kqrl3rv	31	1	Immunity	immunity	NN
cord-347298-7kqrl3rv	31	2	involves	involve	VBZ
cord-347298-7kqrl3rv	31	3	specialized	specialized	JJ
cord-347298-7kqrl3rv	31	4	cells	cell	NNS
cord-347298-7kqrl3rv	31	5	possessing	possess	VBG
cord-347298-7kqrl3rv	31	6	highly	highly	RB
cord-347298-7kqrl3rv	31	7	developed	develop	VBN
cord-347298-7kqrl3rv	31	8	recognition	recognition	NN
cord-347298-7kqrl3rv	31	9	and	and	CC
cord-347298-7kqrl3rv	31	10	activation	activation	NN
cord-347298-7kqrl3rv	31	11	abilities	ability	NNS
cord-347298-7kqrl3rv	31	12	(	(	-LRB-
cord-347298-7kqrl3rv	31	13	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	31	14	and	and	CC
cord-347298-7kqrl3rv	31	15	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	31	16	cells	cell	NNS
cord-347298-7kqrl3rv	31	17	)	)	-RRB-
cord-347298-7kqrl3rv	31	18	and	and	CC
cord-347298-7kqrl3rv	31	19	the	the	DT
cord-347298-7kqrl3rv	31	20	cells	cell	NNS
cord-347298-7kqrl3rv	31	21	that	that	WDT
cord-347298-7kqrl3rv	31	22	carry	carry	VBP
cord-347298-7kqrl3rv	31	23	out	out	RP
cord-347298-7kqrl3rv	31	24	the	the	DT
cord-347298-7kqrl3rv	31	25	protective	protective	JJ
cord-347298-7kqrl3rv	31	26	responses	response	NNS
cord-347298-7kqrl3rv	31	27	:	:	:
cord-347298-7kqrl3rv	31	28	T	T	NNP
cord-347298-7kqrl3rv	31	29	and	and	CC
cord-347298-7kqrl3rv	31	30	B	B	NNP
cord-347298-7kqrl3rv	31	31	cells	cell	NNS
cord-347298-7kqrl3rv	31	32	in	in	IN
cord-347298-7kqrl3rv	31	33	the	the	DT
cord-347298-7kqrl3rv	31	34	case	case	NN
cord-347298-7kqrl3rv	31	35	of	of	IN
cord-347298-7kqrl3rv	31	36	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	31	37	immunity	immunity	NN
cord-347298-7kqrl3rv	31	38	and	and	CC
cord-347298-7kqrl3rv	31	39	NK	NK	NNP
cord-347298-7kqrl3rv	31	40	cells	cell	NNS
cord-347298-7kqrl3rv	31	41	and	and	CC
cord-347298-7kqrl3rv	31	42	mononuclear	mononuclear	JJ
cord-347298-7kqrl3rv	31	43	or	or	CC
cord-347298-7kqrl3rv	31	44	polymorphonuclear	polymorphonuclear	JJ
cord-347298-7kqrl3rv	31	45	phagocytes	phagocyte	NNS
cord-347298-7kqrl3rv	31	46	(	(	-LRB-
cord-347298-7kqrl3rv	31	47	PMNs	PMNs	NNP
cord-347298-7kqrl3rv	31	48	)	)	-RRB-
cord-347298-7kqrl3rv	31	49	in	in	IN
cord-347298-7kqrl3rv	31	50	the	the	DT
cord-347298-7kqrl3rv	31	51	case	case	NN
cord-347298-7kqrl3rv	31	52	of	of	IN
cord-347298-7kqrl3rv	31	53	innate	innate	JJ
cord-347298-7kqrl3rv	31	54	immunity	immunity	NN
cord-347298-7kqrl3rv	31	55	.	.	.
cord-347298-7kqrl3rv	32	1	Many	many	JJ
cord-347298-7kqrl3rv	32	2	of	of	IN
cord-347298-7kqrl3rv	32	3	these	these	DT
cord-347298-7kqrl3rv	32	4	cells	cell	NNS
cord-347298-7kqrl3rv	32	5	play	play	VBP
cord-347298-7kqrl3rv	32	6	roles	role	NNS
cord-347298-7kqrl3rv	32	7	in	in	IN
cord-347298-7kqrl3rv	32	8	both	both	CC
cord-347298-7kqrl3rv	32	9	the	the	DT
cord-347298-7kqrl3rv	32	10	recognition	recognition	NN
cord-347298-7kqrl3rv	32	11	and	and	CC
cord-347298-7kqrl3rv	32	12	effector	effector	VB
cord-347298-7kqrl3rv	32	13	arms	arm	NNS
cord-347298-7kqrl3rv	32	14	of	of	IN
cord-347298-7kqrl3rv	32	15	the	the	DT
cord-347298-7kqrl3rv	32	16	immune	immune	JJ
cord-347298-7kqrl3rv	32	17	response	response	NN
cord-347298-7kqrl3rv	32	18	and	and	CC
cord-347298-7kqrl3rv	32	19	in	in	IN
cord-347298-7kqrl3rv	32	20	both	both	DT
cord-347298-7kqrl3rv	32	21	innate	innate	JJ
cord-347298-7kqrl3rv	32	22	and	and	CC
cord-347298-7kqrl3rv	32	23	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	32	24	immunities	immunity	NNS
cord-347298-7kqrl3rv	32	25	(	(	-LRB-
cord-347298-7kqrl3rv	32	26	Figure	figure	NN
cord-347298-7kqrl3rv	32	27	1	1	CD
cord-347298-7kqrl3rv	32	28	)	)	-RRB-
cord-347298-7kqrl3rv	32	29	.	.	.
cord-347298-7kqrl3rv	33	1	Innate	innate	JJ
cord-347298-7kqrl3rv	33	2	immunity	immunity	NN
cord-347298-7kqrl3rv	33	3	provides	provide	VBZ
cord-347298-7kqrl3rv	33	4	the	the	DT
cord-347298-7kqrl3rv	33	5	rapid	rapid	JJ
cord-347298-7kqrl3rv	33	6	response	response	NN
cord-347298-7kqrl3rv	33	7	elements	element	NNS
cord-347298-7kqrl3rv	33	8	of	of	IN
cord-347298-7kqrl3rv	33	9	the	the	DT
cord-347298-7kqrl3rv	33	10	immune	immune	JJ
cord-347298-7kqrl3rv	33	11	system	system	NN
cord-347298-7kqrl3rv	33	12	,	,	,
cord-347298-7kqrl3rv	33	13	but	but	CC
cord-347298-7kqrl3rv	33	14	is	be	VBZ
cord-347298-7kqrl3rv	33	15	limited	limit	VBN
cord-347298-7kqrl3rv	33	16	in	in	IN
cord-347298-7kqrl3rv	33	17	its	-PRON-	PRP$
cord-347298-7kqrl3rv	33	18	attack	attack	NN
cord-347298-7kqrl3rv	33	19	repertoire	repertoire	NN
cord-347298-7kqrl3rv	33	20	.	.	.
cord-347298-7kqrl3rv	34	1	Adaptive	adaptive	JJ
cord-347298-7kqrl3rv	34	2	immunity	immunity	NN
cord-347298-7kqrl3rv	34	3	is	be	VBZ
cord-347298-7kqrl3rv	34	4	much	much	RB
cord-347298-7kqrl3rv	34	5	more	more	RBR
cord-347298-7kqrl3rv	34	6	flexible	flexible	JJ
cord-347298-7kqrl3rv	34	7	in	in	IN
cord-347298-7kqrl3rv	34	8	its	-PRON-	PRP$
cord-347298-7kqrl3rv	34	9	responses	response	NNS
cord-347298-7kqrl3rv	34	10	,	,	,
cord-347298-7kqrl3rv	34	11	but	but	CC
cord-347298-7kqrl3rv	34	12	requires	require	VBZ
cord-347298-7kqrl3rv	34	13	some	some	DT
cord-347298-7kqrl3rv	34	14	time	time	NN
cord-347298-7kqrl3rv	34	15	to	to	TO
cord-347298-7kqrl3rv	34	16	become	become	VB
cord-347298-7kqrl3rv	34	17	effective	effective	JJ
cord-347298-7kqrl3rv	34	18	.	.	.
cord-347298-7kqrl3rv	35	1	Once	once	IN
cord-347298-7kqrl3rv	35	2	the	the	DT
cord-347298-7kqrl3rv	35	3	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	35	4	arm	arm	NN
cord-347298-7kqrl3rv	35	5	has	have	VBZ
cord-347298-7kqrl3rv	35	6	been	be	VBN
cord-347298-7kqrl3rv	35	7	activated	activate	VBN
cord-347298-7kqrl3rv	35	8	toward	toward	IN
cord-347298-7kqrl3rv	35	9	a	a	DT
cord-347298-7kqrl3rv	35	10	particular	particular	JJ
cord-347298-7kqrl3rv	35	11	pathogen	pathogen	NN
cord-347298-7kqrl3rv	35	12	,	,	,
cord-347298-7kqrl3rv	35	13	however	however	RB
cord-347298-7kqrl3rv	35	14	,	,	,
cord-347298-7kqrl3rv	35	15	it	-PRON-	PRP
cord-347298-7kqrl3rv	35	16	can	can	MD
cord-347298-7kqrl3rv	35	17	respond	respond	VB
cord-347298-7kqrl3rv	35	18	rapidly	rapidly	RB
cord-347298-7kqrl3rv	35	19	in	in	IN
cord-347298-7kqrl3rv	35	20	the	the	DT
cord-347298-7kqrl3rv	35	21	future	future	NN
cord-347298-7kqrl3rv	35	22	due	due	IN
cord-347298-7kqrl3rv	35	23	to	to	IN
cord-347298-7kqrl3rv	35	24	the	the	DT
cord-347298-7kqrl3rv	35	25	persistence	persistence	NN
cord-347298-7kqrl3rv	35	26	of	of	IN
cord-347298-7kqrl3rv	35	27	memory	memory	NN
cord-347298-7kqrl3rv	35	28	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	35	29	,	,	,
cord-347298-7kqrl3rv	35	30	which	which	WDT
cord-347298-7kqrl3rv	35	31	form	form	VBP
cord-347298-7kqrl3rv	35	32	the	the	DT
cord-347298-7kqrl3rv	35	33	basis	basis	NN
cord-347298-7kqrl3rv	35	34	of	of	IN
cord-347298-7kqrl3rv	35	35	immunization	immunization	NN
cord-347298-7kqrl3rv	35	36	(	(	-LRB-
cord-347298-7kqrl3rv	35	37	McGhee	McGhee	NNP
cord-347298-7kqrl3rv	35	38	et	et	NNP
cord-347298-7kqrl3rv	35	39	al	al	NNP
cord-347298-7kqrl3rv	35	40	.	.	NNP
cord-347298-7kqrl3rv	35	41	1993	1993	CD
cord-347298-7kqrl3rv	35	42	;	;	:
cord-347298-7kqrl3rv	35	43	Schittek	Schittek	NNP
cord-347298-7kqrl3rv	35	44	and	and	CC
cord-347298-7kqrl3rv	35	45	Rajewsky	Rajewsky	NNP
cord-347298-7kqrl3rv	35	46	1990	1990	CD
cord-347298-7kqrl3rv	35	47	)	)	-RRB-
cord-347298-7kqrl3rv	35	48	.	.	.
cord-347298-7kqrl3rv	36	1	The	the	DT
cord-347298-7kqrl3rv	36	2	innate	innate	JJ
cord-347298-7kqrl3rv	36	3	immune	immune	JJ
cord-347298-7kqrl3rv	36	4	system	system	NN
cord-347298-7kqrl3rv	36	5	operates	operate	VBZ
cord-347298-7kqrl3rv	36	6	upon	upon	IN
cord-347298-7kqrl3rv	36	7	recognition	recognition	NN
cord-347298-7kqrl3rv	36	8	by	by	IN
cord-347298-7kqrl3rv	36	9	specific	specific	JJ
cord-347298-7kqrl3rv	36	10	pattern	pattern	NN
cord-347298-7kqrl3rv	36	11	-	-	HYPH
cord-347298-7kqrl3rv	36	12	recognition	recognition	NN
cord-347298-7kqrl3rv	36	13	receptors	receptor	NNS
cord-347298-7kqrl3rv	36	14	of	of	IN
cord-347298-7kqrl3rv	36	15	specific	specific	JJ
cord-347298-7kqrl3rv	36	16	motifs	motif	NNS
cord-347298-7kqrl3rv	36	17	found	find	VBN
cord-347298-7kqrl3rv	36	18	on	on	IN
cord-347298-7kqrl3rv	36	19	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	36	20	,	,	,
cord-347298-7kqrl3rv	36	21	viral	viral	JJ
cord-347298-7kqrl3rv	36	22	,	,	,
cord-347298-7kqrl3rv	36	23	fungal	fungal	JJ
cord-347298-7kqrl3rv	36	24	,	,	,
cord-347298-7kqrl3rv	36	25	and	and	CC
cord-347298-7kqrl3rv	36	26	protozoan	protozoan	NN
cord-347298-7kqrl3rv	36	27	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	36	28	.	.	.
cord-347298-7kqrl3rv	37	1	Functionally	functionally	RB
cord-347298-7kqrl3rv	37	2	,	,	,
cord-347298-7kqrl3rv	37	3	these	these	DT
cord-347298-7kqrl3rv	37	4	receptors	receptor	NNS
cord-347298-7kqrl3rv	37	5	have	have	VBP
cord-347298-7kqrl3rv	37	6	evolved	evolve	VBN
cord-347298-7kqrl3rv	37	7	to	to	TO
cord-347298-7kqrl3rv	37	8	recognize	recognize	VB
cord-347298-7kqrl3rv	37	9	pathogen	pathogen	NN
cord-347298-7kqrl3rv	37	10	-	-	HYPH
cord-347298-7kqrl3rv	37	11	associated	associate	VBN
cord-347298-7kqrl3rv	37	12	molecular	molecular	JJ
cord-347298-7kqrl3rv	37	13	patterns	pattern	NNS
cord-347298-7kqrl3rv	37	14	(	(	-LRB-
cord-347298-7kqrl3rv	37	15	PAMPs	pamp	NNS
cord-347298-7kqrl3rv	37	16	)	)	-RRB-
cord-347298-7kqrl3rv	37	17	,	,	,
cord-347298-7kqrl3rv	37	18	such	such	JJ
cord-347298-7kqrl3rv	37	19	as	as	IN
cord-347298-7kqrl3rv	37	20	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	37	21	lipopolysaccharides	lipopolysaccharide	NNS
cord-347298-7kqrl3rv	37	22	(	(	-LRB-
cord-347298-7kqrl3rv	37	23	LPSs	LPSs	NNP
cord-347298-7kqrl3rv	37	24	)	)	-RRB-
cord-347298-7kqrl3rv	37	25	,	,	,
cord-347298-7kqrl3rv	37	26	lipoproteins	lipoprotein	NNS
cord-347298-7kqrl3rv	37	27	,	,	,
cord-347298-7kqrl3rv	37	28	peptidoglycans	peptidoglycan	NNS
cord-347298-7kqrl3rv	37	29	,	,	,
cord-347298-7kqrl3rv	37	30	and	and	CC
cord-347298-7kqrl3rv	37	31	viral	viral	JJ
cord-347298-7kqrl3rv	37	32	nucleic	nucleic	JJ
cord-347298-7kqrl3rv	37	33	acids	acid	NNS
cord-347298-7kqrl3rv	37	34	(	(	-LRB-
cord-347298-7kqrl3rv	37	35	Bianchi	Bianchi	NNP
cord-347298-7kqrl3rv	37	36	2007	2007	CD
cord-347298-7kqrl3rv	37	37	;	;	:
cord-347298-7kqrl3rv	37	38	Roach	Roach	NNP
cord-347298-7kqrl3rv	37	39	et	et	NNP
cord-347298-7kqrl3rv	37	40	al	al	NNP
cord-347298-7kqrl3rv	37	41	.	.	NNP
cord-347298-7kqrl3rv	37	42	2005	2005	CD
cord-347298-7kqrl3rv	37	43	)	)	-RRB-
cord-347298-7kqrl3rv	37	44	.	.	.
cord-347298-7kqrl3rv	38	1	Unlike	unlike	IN
cord-347298-7kqrl3rv	38	2	classical	classical	JJ
cord-347298-7kqrl3rv	38	3	ligand	ligand	NN
cord-347298-7kqrl3rv	38	4	receptors	receptor	NNS
cord-347298-7kqrl3rv	38	5	,	,	,
cord-347298-7kqrl3rv	38	6	these	these	DT
cord-347298-7kqrl3rv	38	7	receptors	receptor	NNS
cord-347298-7kqrl3rv	38	8	respond	respond	VBP
cord-347298-7kqrl3rv	38	9	to	to	IN
cord-347298-7kqrl3rv	38	10	multiple	multiple	JJ
cord-347298-7kqrl3rv	38	11	ligands	ligand	NNS
cord-347298-7kqrl3rv	38	12	possessing	possess	VBG
cord-347298-7kqrl3rv	38	13	related	relate	VBN
cord-347298-7kqrl3rv	38	14	,	,	,
cord-347298-7kqrl3rv	38	15	but	but	CC
cord-347298-7kqrl3rv	38	16	not	not	RB
cord-347298-7kqrl3rv	38	17	necessarily	necessarily	RB
cord-347298-7kqrl3rv	38	18	identical	identical	JJ
cord-347298-7kqrl3rv	38	19	,	,	,
cord-347298-7kqrl3rv	38	20	structures	structure	NNS
cord-347298-7kqrl3rv	38	21	.	.	.
cord-347298-7kqrl3rv	39	1	The	the	DT
cord-347298-7kqrl3rv	39	2	largest	large	JJS
cord-347298-7kqrl3rv	39	3	and	and	CC
cord-347298-7kqrl3rv	39	4	best	well	RBS
cord-347298-7kqrl3rv	39	5	-	-	HYPH
cord-347298-7kqrl3rv	39	6	studied	study	VBN
cord-347298-7kqrl3rv	39	7	class	class	NN
cord-347298-7kqrl3rv	39	8	of	of	IN
cord-347298-7kqrl3rv	39	9	pattern	pattern	NN
cord-347298-7kqrl3rv	39	10	-	-	HYPH
cord-347298-7kqrl3rv	39	11	recognition	recognition	NN
cord-347298-7kqrl3rv	39	12	receptors	receptor	NNS
cord-347298-7kqrl3rv	39	13	is	be	VBZ
cord-347298-7kqrl3rv	39	14	the	the	DT
cord-347298-7kqrl3rv	39	15	TLRs	TLRs	NNPS
cord-347298-7kqrl3rv	39	16	,	,	,
cord-347298-7kqrl3rv	39	17	which	which	WDT
cord-347298-7kqrl3rv	39	18	are	be	VBP
cord-347298-7kqrl3rv	39	19	members	member	NNS
cord-347298-7kqrl3rv	39	20	of	of	IN
cord-347298-7kqrl3rv	39	21	a	a	DT
cord-347298-7kqrl3rv	39	22	larger	large	JJR
cord-347298-7kqrl3rv	39	23	family	family	NN
cord-347298-7kqrl3rv	39	24	of	of	IN
cord-347298-7kqrl3rv	39	25	proteins	protein	NNS
cord-347298-7kqrl3rv	39	26	that	that	WDT
cord-347298-7kqrl3rv	39	27	include	include	VBP
cord-347298-7kqrl3rv	39	28	the	the	DT
cord-347298-7kqrl3rv	39	29	interleukin	interleukin	NN
cord-347298-7kqrl3rv	39	30	(	(	-LRB-
cord-347298-7kqrl3rv	39	31	IL	IL	NNP
cord-347298-7kqrl3rv	39	32	)	)	-RRB-
cord-347298-7kqrl3rv	39	33	1	1	CD
cord-347298-7kqrl3rv	39	34	receptor	receptor	NN
cord-347298-7kqrl3rv	39	35	(	(	-LRB-
cord-347298-7kqrl3rv	39	36	IL1R	IL1R	NNP
cord-347298-7kqrl3rv	39	37	)	)	-RRB-
cord-347298-7kqrl3rv	39	38	,	,	,
cord-347298-7kqrl3rv	39	39	and	and	CC
cord-347298-7kqrl3rv	39	40	which	which	WDT
cord-347298-7kqrl3rv	39	41	share	share	VBP
cord-347298-7kqrl3rv	39	42	a	a	DT
cord-347298-7kqrl3rv	39	43	conserved	conserved	JJ
cord-347298-7kqrl3rv	39	44	cytoplasmic	cytoplasmic	JJ
cord-347298-7kqrl3rv	39	45	domain	domain	NN
cord-347298-7kqrl3rv	39	46	called	call	VBN
cord-347298-7kqrl3rv	39	47	the	the	DT
cord-347298-7kqrl3rv	39	48	Toll	toll	NN
cord-347298-7kqrl3rv	40	1	/IL1R	/IL1R	.
cord-347298-7kqrl3rv	40	2	(	(	-LRB-
cord-347298-7kqrl3rv	40	3	TIR	TIR	NNP
cord-347298-7kqrl3rv	40	4	)	)	-RRB-
cord-347298-7kqrl3rv	40	5	domain	domain	NN
cord-347298-7kqrl3rv	40	6	(	(	-LRB-
cord-347298-7kqrl3rv	40	7	Akira	Akira	NNP
cord-347298-7kqrl3rv	40	8	and	and	CC
cord-347298-7kqrl3rv	40	9	Takeda	Takeda	NNP
cord-347298-7kqrl3rv	40	10	2004	2004	CD
cord-347298-7kqrl3rv	40	11	;	;	:
cord-347298-7kqrl3rv	40	12	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	40	13	and	and	CC
cord-347298-7kqrl3rv	40	14	Bowie	Bowie	NNP
cord-347298-7kqrl3rv	40	15	2007	2007	CD
cord-347298-7kqrl3rv	40	16	)	)	-RRB-
cord-347298-7kqrl3rv	40	17	.	.	.
cord-347298-7kqrl3rv	41	1	In	in	IN
cord-347298-7kqrl3rv	41	2	humans	human	NNS
cord-347298-7kqrl3rv	41	3	,	,	,
cord-347298-7kqrl3rv	41	4	10	10	CD
cord-347298-7kqrl3rv	41	5	functional	functional	JJ
cord-347298-7kqrl3rv	41	6	TLRs	tlr	NNS
cord-347298-7kqrl3rv	41	7	(	(	-LRB-
cord-347298-7kqrl3rv	41	8	TLR1	TLR1	NNP
cord-347298-7kqrl3rv	41	9	-	-	HYPH
cord-347298-7kqrl3rv	41	10	10	10	CD
cord-347298-7kqrl3rv	41	11	)	)	-RRB-
cord-347298-7kqrl3rv	41	12	have	have	VBP
cord-347298-7kqrl3rv	41	13	been	be	VBN
cord-347298-7kqrl3rv	41	14	identified	identify	VBN
cord-347298-7kqrl3rv	41	15	(	(	-LRB-
cord-347298-7kqrl3rv	41	16	Figure	figure	NN
cord-347298-7kqrl3rv	41	17	2	2	CD
cord-347298-7kqrl3rv	41	18	)	)	-RRB-
cord-347298-7kqrl3rv	41	19	.	.	.
cord-347298-7kqrl3rv	42	1	Mammalian	mammalian	JJ
cord-347298-7kqrl3rv	42	2	TLRs	TLRs	NNP
cord-347298-7kqrl3rv	42	3	11	11	CD
cord-347298-7kqrl3rv	42	4	-	-	SYM
cord-347298-7kqrl3rv	42	5	13	13	CD
cord-347298-7kqrl3rv	42	6	are	be	VBP
cord-347298-7kqrl3rv	42	7	known	know	VBN
cord-347298-7kqrl3rv	42	8	from	from	IN
cord-347298-7kqrl3rv	42	9	laboratory	laboratory	NN
cord-347298-7kqrl3rv	42	10	rodent	rodent	NN
cord-347298-7kqrl3rv	42	11	species	specie	NNS
cord-347298-7kqrl3rv	42	12	,	,	,
cord-347298-7kqrl3rv	42	13	but	but	CC
cord-347298-7kqrl3rv	42	14	are	be	VBP
cord-347298-7kqrl3rv	42	15	either	either	CC
cord-347298-7kqrl3rv	42	16	pseudogenes	pseudogene	NNS
cord-347298-7kqrl3rv	42	17	or	or	CC
cord-347298-7kqrl3rv	42	18	absent	absent	JJ
cord-347298-7kqrl3rv	42	19	in	in	IN
cord-347298-7kqrl3rv	42	20	humans	human	NNS
cord-347298-7kqrl3rv	42	21	(	(	-LRB-
cord-347298-7kqrl3rv	42	22	Roach	Roach	NNP
cord-347298-7kqrl3rv	42	23	et	et	NNP
cord-347298-7kqrl3rv	42	24	al	al	NNP
cord-347298-7kqrl3rv	42	25	.	.	NNP
cord-347298-7kqrl3rv	42	26	2005	2005	CD
cord-347298-7kqrl3rv	42	27	)	)	-RRB-
cord-347298-7kqrl3rv	42	28	.	.	.
cord-347298-7kqrl3rv	43	1	Although	although	IN
cord-347298-7kqrl3rv	43	2	they	-PRON-	PRP
cord-347298-7kqrl3rv	43	3	are	be	VBP
cord-347298-7kqrl3rv	43	4	particularly	particularly	RB
cord-347298-7kqrl3rv	43	5	associated	associate	VBN
cord-347298-7kqrl3rv	43	6	with	with	IN
cord-347298-7kqrl3rv	43	7	cells	cell	NNS
cord-347298-7kqrl3rv	43	8	of	of	IN
cord-347298-7kqrl3rv	43	9	the	the	DT
cord-347298-7kqrl3rv	43	10	monocyte	monocyte	NNP
cord-347298-7kqrl3rv	43	11	lineage	lineage	NN
cord-347298-7kqrl3rv	43	12	(	(	-LRB-
cord-347298-7kqrl3rv	43	13	i.e.	i.e.	FW
cord-347298-7kqrl3rv	43	14	,	,	,
cord-347298-7kqrl3rv	43	15	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	43	16	and	and	CC
cord-347298-7kqrl3rv	43	17	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	43	18	cells	cell	NNS
cord-347298-7kqrl3rv	43	19	)	)	-RRB-
cord-347298-7kqrl3rv	43	20	,	,	,
cord-347298-7kqrl3rv	43	21	these	these	DT
cord-347298-7kqrl3rv	43	22	receptors	receptor	NNS
cord-347298-7kqrl3rv	43	23	are	be	VBP
cord-347298-7kqrl3rv	43	24	also	also	RB
cord-347298-7kqrl3rv	43	25	found	find	VBN
cord-347298-7kqrl3rv	43	26	on	on	IN
cord-347298-7kqrl3rv	43	27	certain	certain	JJ
cord-347298-7kqrl3rv	43	28	T	t	NN
cord-347298-7kqrl3rv	43	29	and	and	CC
cord-347298-7kqrl3rv	43	30	B	b	NN
cord-347298-7kqrl3rv	43	31	cells	cell	NNS
cord-347298-7kqrl3rv	43	32	,	,	,
cord-347298-7kqrl3rv	43	33	as	as	RB
cord-347298-7kqrl3rv	43	34	well	well	RB
cord-347298-7kqrl3rv	43	35	as	as	IN
cord-347298-7kqrl3rv	43	36	many	many	JJ
cord-347298-7kqrl3rv	43	37	fibroblastic	fibroblastic	JJ
cord-347298-7kqrl3rv	43	38	and	and	CC
cord-347298-7kqrl3rv	43	39	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	43	40	cells	cell	NNS
cord-347298-7kqrl3rv	43	41	,	,	,
cord-347298-7kqrl3rv	43	42	including	include	VBG
cord-347298-7kqrl3rv	43	43	those	those	DT
cord-347298-7kqrl3rv	43	44	of	of	IN
cord-347298-7kqrl3rv	43	45	the	the	DT
cord-347298-7kqrl3rv	43	46	male	male	JJ
cord-347298-7kqrl3rv	43	47	urogenital	urogenital	JJ
cord-347298-7kqrl3rv	43	48	tract	tract	NN
cord-347298-7kqrl3rv	43	49	(	(	-LRB-
cord-347298-7kqrl3rv	43	50	Lauw	Lauw	NNP
cord-347298-7kqrl3rv	43	51	et	et	NNP
cord-347298-7kqrl3rv	43	52	al	al	NNP
cord-347298-7kqrl3rv	43	53	.	.	NNP
cord-347298-7kqrl3rv	43	54	2005	2005	CD
cord-347298-7kqrl3rv	43	55	;	;	.
cord-347298-7kqrl3rv	44	1	Zhang	Zhang	NNP
cord-347298-7kqrl3rv	44	2	et	et	NNP
cord-347298-7kqrl3rv	44	3	al	al	NNP
cord-347298-7kqrl3rv	44	4	.	.	.
cord-347298-7kqrl3rv	44	5	2004	2004	CD
cord-347298-7kqrl3rv	44	6	)	)	-RRB-
cord-347298-7kqrl3rv	44	7	.	.	.
cord-347298-7kqrl3rv	45	1	Significantly	significantly	RB
cord-347298-7kqrl3rv	45	2	,	,	,
cord-347298-7kqrl3rv	45	3	ligands	ligand	NNS
cord-347298-7kqrl3rv	45	4	for	for	IN
cord-347298-7kqrl3rv	45	5	some	some	DT
cord-347298-7kqrl3rv	45	6	of	of	IN
cord-347298-7kqrl3rv	45	7	the	the	DT
cord-347298-7kqrl3rv	45	8	TLRs	tlr	NNS
cord-347298-7kqrl3rv	45	9	include	include	VBP
cord-347298-7kqrl3rv	45	10	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	45	11	molecules	molecule	NNS
cord-347298-7kqrl3rv	45	12	of	of	IN
cord-347298-7kqrl3rv	45	13	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	45	14	origin	origin	NN
cord-347298-7kqrl3rv	46	1	(	(	-LRB-
cord-347298-7kqrl3rv	46	2	Barrat	Barrat	NNP
cord-347298-7kqrl3rv	46	3	et	et	NNP
cord-347298-7kqrl3rv	46	4	al	al	NNP
cord-347298-7kqrl3rv	46	5	.	.	.
cord-347298-7kqrl3rv	46	6	2005	2005	CD
cord-347298-7kqrl3rv	47	1	;	;	:
cord-347298-7kqrl3rv	47	2	Karikó	Karikó	NNP
cord-347298-7kqrl3rv	47	3	et	et	FW
cord-347298-7kqrl3rv	47	4	al	al	NNP
cord-347298-7kqrl3rv	47	5	.	.	.
cord-347298-7kqrl3rv	48	1	2004	2004	CD
cord-347298-7kqrl3rv	48	2	;	;	:
cord-347298-7kqrl3rv	48	3	Tsan	Tsan	NNP
cord-347298-7kqrl3rv	48	4	and	and	CC
cord-347298-7kqrl3rv	48	5	Gao	Gao	NNP
cord-347298-7kqrl3rv	48	6	2004	2004	CD
cord-347298-7kqrl3rv	48	7	;	;	:
cord-347298-7kqrl3rv	48	8	Yasuda	Yasuda	NNP
cord-347298-7kqrl3rv	48	9	et	et	NNP
cord-347298-7kqrl3rv	48	10	al	al	NNP
cord-347298-7kqrl3rv	48	11	.	.	.
cord-347298-7kqrl3rv	49	1	2005	2005	CD
cord-347298-7kqrl3rv	49	2	;	;	:
cord-347298-7kqrl3rv	49	3	Yu	Yu	NNP
cord-347298-7kqrl3rv	49	4	et	et	NNP
cord-347298-7kqrl3rv	49	5	al	al	NNP
cord-347298-7kqrl3rv	49	6	.	.	.
cord-347298-7kqrl3rv	49	7	2006	2006	CD
cord-347298-7kqrl3rv	49	8	)	)	-RRB-
cord-347298-7kqrl3rv	49	9	.	.	.
cord-347298-7kqrl3rv	50	1	TLR	TLR	NNP
cord-347298-7kqrl3rv	50	2	signaling	signal	VBG
cord-347298-7kqrl3rv	50	3	occurs	occur	VBZ
cord-347298-7kqrl3rv	50	4	through	through	IN
cord-347298-7kqrl3rv	50	5	engagement	engagement	NN
cord-347298-7kqrl3rv	50	6	of	of	IN
cord-347298-7kqrl3rv	50	7	crucial	crucial	JJ
cord-347298-7kqrl3rv	50	8	adaptor	adaptor	NN
cord-347298-7kqrl3rv	50	9	proteins	protein	NNS
cord-347298-7kqrl3rv	50	10	,	,	,
cord-347298-7kqrl3rv	50	11	specifically	specifically	RB
cord-347298-7kqrl3rv	50	12	myeloid	myeloid	JJ
cord-347298-7kqrl3rv	50	13	differentiation	differentiation	NN
cord-347298-7kqrl3rv	50	14	primary	primary	JJ
cord-347298-7kqrl3rv	50	15	response	response	NN
cord-347298-7kqrl3rv	50	16	protein	protein	NN
cord-347298-7kqrl3rv	50	17	88	88	CD
cord-347298-7kqrl3rv	50	18	(	(	-LRB-
cord-347298-7kqrl3rv	50	19	MyD88	MyD88	NNS
cord-347298-7kqrl3rv	50	20	)	)	-RRB-
cord-347298-7kqrl3rv	50	21	or	or	CC
cord-347298-7kqrl3rv	50	22	TIR	TIR	NNP
cord-347298-7kqrl3rv	50	23	domain	domain	NN
cord-347298-7kqrl3rv	50	24	-	-	HYPH
cord-347298-7kqrl3rv	50	25	containing	contain	VBG
cord-347298-7kqrl3rv	50	26	adaptor	adaptor	NN
cord-347298-7kqrl3rv	50	27	protein	protein	NN
cord-347298-7kqrl3rv	50	28	inducing	induce	VBG
cord-347298-7kqrl3rv	50	29	interferon	interferon	NN
cord-347298-7kqrl3rv	50	30	(	(	-LRB-
cord-347298-7kqrl3rv	50	31	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	50	32	)	)	-RRB-
cord-347298-7kqrl3rv	50	33	,	,	,
cord-347298-7kqrl3rv	50	34	via	via	IN
cord-347298-7kqrl3rv	50	35	TIR	TIR	NNP
cord-347298-7kqrl3rv	50	36	domain	domain	NN
cord-347298-7kqrl3rv	50	37	interactions	interaction	NNS
cord-347298-7kqrl3rv	50	38	,	,	,
cord-347298-7kqrl3rv	50	39	leading	lead	VBG
cord-347298-7kqrl3rv	50	40	to	to	IN
cord-347298-7kqrl3rv	50	41	activation	activation	NN
cord-347298-7kqrl3rv	50	42	of	of	IN
cord-347298-7kqrl3rv	50	43	tumor	tumor	NN
cord-347298-7kqrl3rv	50	44	necrosis	necrosis	NN
cord-347298-7kqrl3rv	50	45	factor	factor	NN
cord-347298-7kqrl3rv	50	46	(	(	-LRB-
cord-347298-7kqrl3rv	50	47	TNF	TNF	NNP
cord-347298-7kqrl3rv	50	48	)	)	-RRB-
cord-347298-7kqrl3rv	50	49	receptorassociated	receptorassociate	VBD
cord-347298-7kqrl3rv	50	50	factor	factor	NN
cord-347298-7kqrl3rv	50	51	3	3	CD
cord-347298-7kqrl3rv	50	52	and	and	CC
cord-347298-7kqrl3rv	50	53	6	6	CD
cord-347298-7kqrl3rv	50	54	(	(	-LRB-
cord-347298-7kqrl3rv	50	55	TRAF3	TRAF3	NNP
cord-347298-7kqrl3rv	50	56	,	,	,
cord-347298-7kqrl3rv	50	57	TRAF6	TRAF6	NNP
cord-347298-7kqrl3rv	50	58	)	)	-RRB-
cord-347298-7kqrl3rv	51	1	(	(	-LRB-
cord-347298-7kqrl3rv	51	2	Akira	Akira	NNP
cord-347298-7kqrl3rv	51	3	and	and	CC
cord-347298-7kqrl3rv	51	4	Takeda	Takeda	NNP
cord-347298-7kqrl3rv	51	5	2004	2004	CD
cord-347298-7kqrl3rv	51	6	;	;	:
cord-347298-7kqrl3rv	51	7	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	51	8	and	and	CC
cord-347298-7kqrl3rv	51	9	Bowie	Bowie	NNP
cord-347298-7kqrl3rv	51	10	2007	2007	CD
cord-347298-7kqrl3rv	51	11	;	;	:
cord-347298-7kqrl3rv	51	12	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	51	13	and	and	CC
cord-347298-7kqrl3rv	51	14	Dinarello	Dinarello	NNP
cord-347298-7kqrl3rv	51	15	2000	2000	CD
cord-347298-7kqrl3rv	51	16	)	)	-RRB-
cord-347298-7kqrl3rv	51	17	.	.	.
cord-347298-7kqrl3rv	52	1	Based	base	VBN
cord-347298-7kqrl3rv	52	2	on	on	IN
cord-347298-7kqrl3rv	52	3	the	the	DT
cord-347298-7kqrl3rv	52	4	TLR	TLR	NNP
cord-347298-7kqrl3rv	52	5	engaged	engage	VBD
cord-347298-7kqrl3rv	52	6	,	,	,
cord-347298-7kqrl3rv	52	7	this	this	DT
cord-347298-7kqrl3rv	52	8	results	result	NNS
cord-347298-7kqrl3rv	52	9	in	in	IN
cord-347298-7kqrl3rv	52	10	nuclear	nuclear	JJ
cord-347298-7kqrl3rv	52	11	translocation	translocation	NN
cord-347298-7kqrl3rv	52	12	of	of	IN
cord-347298-7kqrl3rv	52	13	the	the	DT
cord-347298-7kqrl3rv	52	14	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	52	15	transcription	transcription	NN
cord-347298-7kqrl3rv	52	16	factor	factor	NN
cord-347298-7kqrl3rv	52	17	,	,	,
cord-347298-7kqrl3rv	52	18	nuclear	nuclear	JJ
cord-347298-7kqrl3rv	52	19	factor	factor	NN
cord-347298-7kqrl3rv	52	20	kappa	kappa	NNP
cord-347298-7kqrl3rv	52	21	B	B	NNP
cord-347298-7kqrl3rv	52	22	(	(	-LRB-
cord-347298-7kqrl3rv	52	23	NFB	NFB	NNP
cord-347298-7kqrl3rv	52	24	)	)	-RRB-
cord-347298-7kqrl3rv	52	25	,	,	,
cord-347298-7kqrl3rv	52	26	activation	activation	NN
cord-347298-7kqrl3rv	52	27	of	of	IN
cord-347298-7kqrl3rv	52	28	the	the	DT
cord-347298-7kqrl3rv	52	29	Jun	Jun	NNP
cord-347298-7kqrl3rv	52	30	N	N	NNP
cord-347298-7kqrl3rv	52	31	-	-	HYPH
cord-347298-7kqrl3rv	52	32	terminal	terminal	NN
cord-347298-7kqrl3rv	52	33	kinase	kinase	NN
cord-347298-7kqrl3rv	52	34	(	(	-LRB-
cord-347298-7kqrl3rv	52	35	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	52	36	)	)	-RRB-
cord-347298-7kqrl3rv	52	37	and	and	CC
cord-347298-7kqrl3rv	52	38	p38	p38	CD
cord-347298-7kqrl3rv	52	39	mitogen	mitogen	NNP
cord-347298-7kqrl3rv	52	40	-	-	HYPH
cord-347298-7kqrl3rv	52	41	activated	activate	VBN
cord-347298-7kqrl3rv	52	42	protein	protein	NN
cord-347298-7kqrl3rv	52	43	(	(	-LRB-
cord-347298-7kqrl3rv	52	44	MAP	MAP	NNP
cord-347298-7kqrl3rv	52	45	)	)	-RRB-
cord-347298-7kqrl3rv	52	46	kinases	kinase	NNS
cord-347298-7kqrl3rv	52	47	,	,	,
cord-347298-7kqrl3rv	52	48	and	and	CC
cord-347298-7kqrl3rv	52	49	induction	induction	NN
cord-347298-7kqrl3rv	52	50	of	of	IN
cord-347298-7kqrl3rv	52	51	type	type	NN
cord-347298-7kqrl3rv	52	52	1	1	CD
cord-347298-7kqrl3rv	52	53	interferon	interferon	NN
cord-347298-7kqrl3rv	52	54	(	(	-LRB-
cord-347298-7kqrl3rv	52	55	IFN	IFN	NNP
cord-347298-7kqrl3rv	52	56	and	and	CC
cord-347298-7kqrl3rv	52	57	IFN	IFN	NNP
cord-347298-7kqrl3rv	52	58	)	)	-RRB-
cord-347298-7kqrl3rv	53	1	Figure	figure	NN
cord-347298-7kqrl3rv	53	2	1	1	CD
cord-347298-7kqrl3rv	53	3	Polarization	polarization	NN
cord-347298-7kqrl3rv	53	4	in	in	IN
cord-347298-7kqrl3rv	53	5	the	the	DT
cord-347298-7kqrl3rv	53	6	immune	immune	JJ
cord-347298-7kqrl3rv	53	7	system	system	NN
cord-347298-7kqrl3rv	53	8	.	.	.
cord-347298-7kqrl3rv	54	1	The	the	DT
cord-347298-7kqrl3rv	54	2	immune	immune	JJ
cord-347298-7kqrl3rv	54	3	system	system	NN
cord-347298-7kqrl3rv	54	4	is	be	VBZ
cord-347298-7kqrl3rv	54	5	conceptually	conceptually	RB
cord-347298-7kqrl3rv	54	6	divided	divide	VBN
cord-347298-7kqrl3rv	54	7	into	into	IN
cord-347298-7kqrl3rv	54	8	innate	innate	JJ
cord-347298-7kqrl3rv	54	9	and	and	CC
cord-347298-7kqrl3rv	54	10	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	54	11	arms	arm	NNS
cord-347298-7kqrl3rv	54	12	,	,	,
cord-347298-7kqrl3rv	54	13	with	with	IN
cord-347298-7kqrl3rv	54	14	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	54	15	immunity	immunity	NN
cord-347298-7kqrl3rv	54	16	further	further	RB
cord-347298-7kqrl3rv	54	17	subdivided	subdivide	VBD
cord-347298-7kqrl3rv	54	18	into	into	IN
cord-347298-7kqrl3rv	54	19	type	type	NN
cord-347298-7kqrl3rv	54	20	1	1	CD
cord-347298-7kqrl3rv	54	21	(	(	-LRB-
cord-347298-7kqrl3rv	54	22	cell	cell	NN
cord-347298-7kqrl3rv	54	23	-	-	HYPH
cord-347298-7kqrl3rv	54	24	mediated	mediate	VBN
cord-347298-7kqrl3rv	54	25	)	)	-RRB-
cord-347298-7kqrl3rv	54	26	and	and	CC
cord-347298-7kqrl3rv	54	27	type	type	NN
cord-347298-7kqrl3rv	54	28	2	2	CD
cord-347298-7kqrl3rv	54	29	(	(	-LRB-
cord-347298-7kqrl3rv	54	30	antibody	antibody	NN
cord-347298-7kqrl3rv	54	31	-	-	HYPH
cord-347298-7kqrl3rv	54	32	mediated	mediate	VBN
cord-347298-7kqrl3rv	54	33	)	)	-RRB-
cord-347298-7kqrl3rv	54	34	responses	response	NNS
cord-347298-7kqrl3rv	54	35	.	.	.
cord-347298-7kqrl3rv	55	1	Triggering	trigger	VBG
cord-347298-7kqrl3rv	55	2	of	of	IN
cord-347298-7kqrl3rv	55	3	the	the	DT
cord-347298-7kqrl3rv	55	4	immune	immune	JJ
cord-347298-7kqrl3rv	55	5	response	response	NN
cord-347298-7kqrl3rv	55	6	involves	involve	VBZ
cord-347298-7kqrl3rv	55	7	the	the	DT
cord-347298-7kqrl3rv	55	8	induction	induction	NN
cord-347298-7kqrl3rv	55	9	of	of	IN
cord-347298-7kqrl3rv	55	10	inflammation	inflammation	NN
cord-347298-7kqrl3rv	55	11	by	by	IN
cord-347298-7kqrl3rv	55	12	various	various	JJ
cord-347298-7kqrl3rv	55	13	agents	agent	NNS
cord-347298-7kqrl3rv	55	14	,	,	,
cord-347298-7kqrl3rv	55	15	which	which	WDT
cord-347298-7kqrl3rv	55	16	may	may	MD
cord-347298-7kqrl3rv	55	17	include	include	VB
cord-347298-7kqrl3rv	55	18	infections	infection	NNS
cord-347298-7kqrl3rv	55	19	,	,	,
cord-347298-7kqrl3rv	55	20	particulates	particulate	NNS
cord-347298-7kqrl3rv	55	21	,	,	,
cord-347298-7kqrl3rv	55	22	debris	debris	NN
cord-347298-7kqrl3rv	55	23	from	from	IN
cord-347298-7kqrl3rv	55	24	damaged	damaged	JJ
cord-347298-7kqrl3rv	55	25	cells	cell	NNS
cord-347298-7kqrl3rv	55	26	,	,	,
cord-347298-7kqrl3rv	55	27	or	or	CC
cord-347298-7kqrl3rv	55	28	noxious	noxious	JJ
cord-347298-7kqrl3rv	55	29	agents	agent	NNS
cord-347298-7kqrl3rv	55	30	.	.	.
cord-347298-7kqrl3rv	56	1	Innate	innate	JJ
cord-347298-7kqrl3rv	56	2	immunity	immunity	NN
cord-347298-7kqrl3rv	56	3	involves	involve	VBZ
cord-347298-7kqrl3rv	56	4	fixed	fix	VBN
cord-347298-7kqrl3rv	56	5	pattern	pattern	NN
cord-347298-7kqrl3rv	56	6	-	-	HYPH
cord-347298-7kqrl3rv	56	7	recognition	recognition	NN
cord-347298-7kqrl3rv	56	8	receptors	receptor	NNS
cord-347298-7kqrl3rv	56	9	,	,	,
cord-347298-7kqrl3rv	56	10	such	such	JJ
cord-347298-7kqrl3rv	56	11	as	as	IN
cord-347298-7kqrl3rv	56	12	the	the	DT
cord-347298-7kqrl3rv	56	13	Tolllike	Tolllike	NNP
cord-347298-7kqrl3rv	56	14	receptors	receptor	NNS
cord-347298-7kqrl3rv	56	15	,	,	,
cord-347298-7kqrl3rv	56	16	whereas	whereas	IN
cord-347298-7kqrl3rv	56	17	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	56	18	immunity	immunity	NN
cord-347298-7kqrl3rv	56	19	depends	depend	VBZ
cord-347298-7kqrl3rv	56	20	upon	upon	IN
cord-347298-7kqrl3rv	56	21	highly	highly	RB
cord-347298-7kqrl3rv	56	22	polymorphic	polymorphic	JJ
cord-347298-7kqrl3rv	56	23	receptors	receptor	NNS
cord-347298-7kqrl3rv	56	24	expressed	express	VBN
cord-347298-7kqrl3rv	56	25	by	by	IN
cord-347298-7kqrl3rv	56	26	T	T	NNP
cord-347298-7kqrl3rv	56	27	cells	cell	NNS
cord-347298-7kqrl3rv	56	28	(	(	-LRB-
cord-347298-7kqrl3rv	56	29	T	T	NNP
cord-347298-7kqrl3rv	56	30	cell	cell	NN
cord-347298-7kqrl3rv	56	31	receptors	receptor	NNS
cord-347298-7kqrl3rv	56	32	)	)	-RRB-
cord-347298-7kqrl3rv	56	33	and	and	CC
cord-347298-7kqrl3rv	56	34	B	b	NN
cord-347298-7kqrl3rv	56	35	cells	cell	NNS
cord-347298-7kqrl3rv	57	1	(	(	-LRB-
cord-347298-7kqrl3rv	57	2	membrane	membrane	NN
cord-347298-7kqrl3rv	57	3	-	-	HYPH
cord-347298-7kqrl3rv	57	4	bound	bind	VBN
cord-347298-7kqrl3rv	57	5	and	and	CC
cord-347298-7kqrl3rv	57	6	secreted	secrete	VBN
cord-347298-7kqrl3rv	57	7	immunoglobulin	immunoglobulin	NN
cord-347298-7kqrl3rv	57	8	)	)	-RRB-
cord-347298-7kqrl3rv	57	9	.	.	.
cord-347298-7kqrl3rv	58	1	In	in	IN
cord-347298-7kqrl3rv	58	2	general	general	JJ
cord-347298-7kqrl3rv	58	3	,	,	,
cord-347298-7kqrl3rv	58	4	type	type	NN
cord-347298-7kqrl3rv	58	5	1	1	CD
cord-347298-7kqrl3rv	58	6	responses	response	NNS
cord-347298-7kqrl3rv	58	7	are	be	VBP
cord-347298-7kqrl3rv	58	8	associated	associate	VBN
cord-347298-7kqrl3rv	58	9	with	with	IN
cord-347298-7kqrl3rv	58	10	cellular	cellular	JJ
cord-347298-7kqrl3rv	58	11	immunity	immunity	NN
cord-347298-7kqrl3rv	58	12	,	,	,
cord-347298-7kqrl3rv	58	13	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	58	14	reactions	reaction	NNS
cord-347298-7kqrl3rv	58	15	,	,	,
cord-347298-7kqrl3rv	58	16	and	and	CC
cord-347298-7kqrl3rv	58	17	graft	graft	NN
cord-347298-7kqrl3rv	58	18	rejection	rejection	NN
cord-347298-7kqrl3rv	58	19	.	.	.
cord-347298-7kqrl3rv	59	1	Type	type	NN
cord-347298-7kqrl3rv	59	2	2	2	CD
cord-347298-7kqrl3rv	59	3	responses	response	NNS
cord-347298-7kqrl3rv	59	4	involve	involve	VBP
cord-347298-7kqrl3rv	59	5	antibody	antibody	NN
cord-347298-7kqrl3rv	59	6	production	production	NN
cord-347298-7kqrl3rv	59	7	by	by	IN
cord-347298-7kqrl3rv	59	8	the	the	DT
cord-347298-7kqrl3rv	59	9	B	b	NN
cord-347298-7kqrl3rv	59	10	cells	cell	NNS
cord-347298-7kqrl3rv	59	11	,	,	,
cord-347298-7kqrl3rv	59	12	but	but	CC
cord-347298-7kqrl3rv	59	13	also	also	RB
cord-347298-7kqrl3rv	59	14	play	play	VBP
cord-347298-7kqrl3rv	59	15	a	a	DT
cord-347298-7kqrl3rv	59	16	more	more	RBR
cord-347298-7kqrl3rv	59	17	complex	complex	JJ
cord-347298-7kqrl3rv	59	18	role	role	NN
cord-347298-7kqrl3rv	59	19	in	in	IN
cord-347298-7kqrl3rv	59	20	allergy	allergy	NN
cord-347298-7kqrl3rv	59	21	,	,	,
cord-347298-7kqrl3rv	59	22	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	59	23	,	,	,
cord-347298-7kqrl3rv	59	24	and	and	CC
cord-347298-7kqrl3rv	59	25	control	control	NN
cord-347298-7kqrl3rv	59	26	of	of	IN
cord-347298-7kqrl3rv	59	27	tolerance	tolerance	NN
cord-347298-7kqrl3rv	59	28	,	,	,
cord-347298-7kqrl3rv	59	29	favoring	favor	VBG
cord-347298-7kqrl3rv	59	30	immune	immune	JJ
cord-347298-7kqrl3rv	59	31	privilege	privilege	NN
cord-347298-7kqrl3rv	59	32	.	.	.
cord-347298-7kqrl3rv	60	1	Within	within	IN
cord-347298-7kqrl3rv	60	2	these	these	DT
cord-347298-7kqrl3rv	60	3	divisions	division	NNS
cord-347298-7kqrl3rv	60	4	,	,	,
cord-347298-7kqrl3rv	60	5	various	various	JJ
cord-347298-7kqrl3rv	60	6	cell	cell	NN
cord-347298-7kqrl3rv	60	7	types	type	NNS
cord-347298-7kqrl3rv	60	8	,	,	,
cord-347298-7kqrl3rv	60	9	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	60	10	,	,	,
cord-347298-7kqrl3rv	60	11	chemokines	chemokine	NNS
cord-347298-7kqrl3rv	60	12	,	,	,
cord-347298-7kqrl3rv	60	13	bioactive	bioactive	JJ
cord-347298-7kqrl3rv	60	14	lipids	lipid	NNS
cord-347298-7kqrl3rv	60	15	,	,	,
cord-347298-7kqrl3rv	60	16	and	and	CC
cord-347298-7kqrl3rv	60	17	other	other	JJ
cord-347298-7kqrl3rv	60	18	molecules	molecule	NNS
cord-347298-7kqrl3rv	60	19	interact	interact	VBP
cord-347298-7kqrl3rv	60	20	to	to	TO
cord-347298-7kqrl3rv	60	21	integrate	integrate	VB
cord-347298-7kqrl3rv	60	22	or	or	CC
cord-347298-7kqrl3rv	60	23	mediate	mediate	VB
cord-347298-7kqrl3rv	60	24	the	the	DT
cord-347298-7kqrl3rv	60	25	responses	response	NNS
cord-347298-7kqrl3rv	60	26	.	.	.
cord-347298-7kqrl3rv	61	1	The	the	DT
cord-347298-7kqrl3rv	61	2	direction	direction	NN
cord-347298-7kqrl3rv	61	3	of	of	IN
cord-347298-7kqrl3rv	61	4	the	the	DT
cord-347298-7kqrl3rv	61	5	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	61	6	immune	immune	JJ
cord-347298-7kqrl3rv	61	7	response	response	NN
cord-347298-7kqrl3rv	61	8	type	type	NN
cord-347298-7kqrl3rv	61	9	is	be	VBZ
cord-347298-7kqrl3rv	61	10	determined	determine	VBN
cord-347298-7kqrl3rv	61	11	primarily	primarily	RB
cord-347298-7kqrl3rv	61	12	by	by	IN
cord-347298-7kqrl3rv	61	13	the	the	DT
cord-347298-7kqrl3rv	61	14	activity	activity	NN
cord-347298-7kqrl3rv	61	15	of	of	IN
cord-347298-7kqrl3rv	61	16	the	the	DT
cord-347298-7kqrl3rv	61	17	antigenpresenting	antigenpresenting	NN
cord-347298-7kqrl3rv	61	18	cells	cell	NNS
cord-347298-7kqrl3rv	61	19	(	(	-LRB-
cord-347298-7kqrl3rv	61	20	primarily	primarily	RB
cord-347298-7kqrl3rv	61	21	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	61	22	cells	cell	NNS
cord-347298-7kqrl3rv	61	23	)	)	-RRB-
cord-347298-7kqrl3rv	61	24	under	under	IN
cord-347298-7kqrl3rv	61	25	the	the	DT
cord-347298-7kqrl3rv	61	26	influence	influence	NN
cord-347298-7kqrl3rv	61	27	of	of	IN
cord-347298-7kqrl3rv	61	28	cells	cell	NNS
cord-347298-7kqrl3rv	61	29	with	with	IN
cord-347298-7kqrl3rv	61	30	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	61	31	capacity	capacity	NN
cord-347298-7kqrl3rv	61	32	,	,	,
cord-347298-7kqrl3rv	61	33	such	such	JJ
cord-347298-7kqrl3rv	61	34	as	as	IN
cord-347298-7kqrl3rv	61	35	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	61	36	,	,	,
cord-347298-7kqrl3rv	61	37	NK	NK	NNP
cord-347298-7kqrl3rv	61	38	cells	cell	NNS
cord-347298-7kqrl3rv	61	39	,	,	,
cord-347298-7kqrl3rv	61	40	and	and	CC
cord-347298-7kqrl3rv	61	41	NKT	NKT	NNP
cord-347298-7kqrl3rv	61	42	cells	cell	NNS
cord-347298-7kqrl3rv	61	43	,	,	,
cord-347298-7kqrl3rv	61	44	and	and	CC
cord-347298-7kqrl3rv	61	45	either	either	DT
cord-347298-7kqrl3rv	61	46	type	type	NN
cord-347298-7kqrl3rv	61	47	1	1	CD
cord-347298-7kqrl3rv	61	48	or	or	CC
cord-347298-7kqrl3rv	61	49	type	type	NN
cord-347298-7kqrl3rv	61	50	2	2	CD
cord-347298-7kqrl3rv	61	51	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	61	52	produced	produce	VBN
cord-347298-7kqrl3rv	61	53	locally	locally	RB
cord-347298-7kqrl3rv	61	54	.	.	.
cord-347298-7kqrl3rv	62	1	Several	several	JJ
cord-347298-7kqrl3rv	62	2	cell	cell	NN
cord-347298-7kqrl3rv	62	3	types	type	NNS
cord-347298-7kqrl3rv	62	4	and	and	CC
cord-347298-7kqrl3rv	62	5	molecules	molecule	NNS
cord-347298-7kqrl3rv	62	6	play	play	VBP
cord-347298-7kqrl3rv	62	7	multiple	multiple	JJ
cord-347298-7kqrl3rv	62	8	roles	role	NNS
cord-347298-7kqrl3rv	62	9	within	within	IN
cord-347298-7kqrl3rv	62	10	different	different	JJ
cord-347298-7kqrl3rv	62	11	functional	functional	JJ
cord-347298-7kqrl3rv	62	12	divisions	division	NNS
cord-347298-7kqrl3rv	62	13	.	.	.
cord-347298-7kqrl3rv	63	1	Abbreviations	abbreviation	NNS
cord-347298-7kqrl3rv	63	2	:	:	:
cord-347298-7kqrl3rv	63	3	Mo	Mo	NNP
cord-347298-7kqrl3rv	63	4	,	,	,
cord-347298-7kqrl3rv	63	5	monocyte	monocyte	NNP
cord-347298-7kqrl3rv	63	6	;	;	:
cord-347298-7kqrl3rv	63	7	NK	NK	NNP
cord-347298-7kqrl3rv	63	8	,	,	,
cord-347298-7kqrl3rv	63	9	natural	natural	JJ
cord-347298-7kqrl3rv	63	10	killer	killer	NN
cord-347298-7kqrl3rv	63	11	cell	cell	NN
cord-347298-7kqrl3rv	63	12	;	;	:
cord-347298-7kqrl3rv	63	13	PMN	PMN	NNP
cord-347298-7kqrl3rv	63	14	,	,	,
cord-347298-7kqrl3rv	63	15	polymorphonuclear	polymorphonuclear	JJ
cord-347298-7kqrl3rv	63	16	cell	cell	NN
cord-347298-7kqrl3rv	63	17	;	;	.
cord-347298-7kqrl3rv	64	1	Th	th	RB
cord-347298-7kqrl3rv	64	2	;	;	:
cord-347298-7kqrl3rv	64	3	helper	helper	NN
cord-347298-7kqrl3rv	64	4	T	t	NN
cord-347298-7kqrl3rv	64	5	cell	cell	NN
cord-347298-7kqrl3rv	64	6	;	;	:
cord-347298-7kqrl3rv	64	7	B	b	NN
cord-347298-7kqrl3rv	64	8	,	,	,
cord-347298-7kqrl3rv	64	9	B	b	NN
cord-347298-7kqrl3rv	64	10	cell	cell	NN
cord-347298-7kqrl3rv	64	11	;	;	:
cord-347298-7kqrl3rv	64	12	T	T	NNP
cord-347298-7kqrl3rv	64	13	reg	reg	NNP
cord-347298-7kqrl3rv	64	14	,	,	,
cord-347298-7kqrl3rv	64	15	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	64	16	T	t	NN
cord-347298-7kqrl3rv	64	17	cell	cell	NN
cord-347298-7kqrl3rv	64	18	;	;	:
cord-347298-7kqrl3rv	64	19	M	M	NNP
cord-347298-7kqrl3rv	64	20	,	,	,
cord-347298-7kqrl3rv	64	21	macrophage	macrophage	NN
cord-347298-7kqrl3rv	64	22	;	;	:
cord-347298-7kqrl3rv	64	23	NKT	NKT	NNP
cord-347298-7kqrl3rv	64	24	,	,	,
cord-347298-7kqrl3rv	64	25	natural	natural	JJ
cord-347298-7kqrl3rv	64	26	killer	killer	NN
cord-347298-7kqrl3rv	64	27	T	t	NN
cord-347298-7kqrl3rv	64	28	cell	cell	NN
cord-347298-7kqrl3rv	64	29	;	;	:
cord-347298-7kqrl3rv	64	30	CTL	CTL	NNP
cord-347298-7kqrl3rv	64	31	,	,	,
cord-347298-7kqrl3rv	64	32	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	64	33	T	t	NN
cord-347298-7kqrl3rv	64	34	cell	cell	NN
cord-347298-7kqrl3rv	64	35	;	;	:
cord-347298-7kqrl3rv	64	36	APC	APC	NNP
cord-347298-7kqrl3rv	64	37	,	,	,
cord-347298-7kqrl3rv	64	38	antigenpresenting	antigenpresente	VBG
cord-347298-7kqrl3rv	64	39	cell	cell	NN
cord-347298-7kqrl3rv	64	40	,	,	,
cord-347298-7kqrl3rv	64	41	ROS	ROS	NNP
cord-347298-7kqrl3rv	64	42	,	,	,
cord-347298-7kqrl3rv	64	43	reactive	reactive	JJ
cord-347298-7kqrl3rv	64	44	oxygen	oxygen	NN
cord-347298-7kqrl3rv	64	45	species	specie	NNS
cord-347298-7kqrl3rv	64	46	;	;	:
cord-347298-7kqrl3rv	64	47	IFN	IFN	NNP
cord-347298-7kqrl3rv	64	48	,	,	,
cord-347298-7kqrl3rv	64	49	interferon	interferon	NN
cord-347298-7kqrl3rv	64	50	;	;	:
cord-347298-7kqrl3rv	64	51	PGE	PGE	NNP
cord-347298-7kqrl3rv	64	52	,	,	,
cord-347298-7kqrl3rv	64	53	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	64	54	E	e	NN
cord-347298-7kqrl3rv	64	55	;	;	:
cord-347298-7kqrl3rv	64	56	COX	COX	NNP
cord-347298-7kqrl3rv	64	57	,	,	,
cord-347298-7kqrl3rv	64	58	cyclooxygenase	cyclooxygenase	NN
cord-347298-7kqrl3rv	64	59	;	;	,
cord-347298-7kqrl3rv	64	60	iNOS	inos	JJ
cord-347298-7kqrl3rv	64	61	,	,	,
cord-347298-7kqrl3rv	64	62	inducible	inducible	JJ
cord-347298-7kqrl3rv	64	63	nitric	nitric	NN
cord-347298-7kqrl3rv	64	64	oxide	oxide	NN
cord-347298-7kqrl3rv	64	65	synthase	synthase	NN
cord-347298-7kqrl3rv	64	66	;	;	:
cord-347298-7kqrl3rv	64	67	TNF	TNF	NNP
cord-347298-7kqrl3rv	64	68	,	,	,
cord-347298-7kqrl3rv	64	69	tumor	tumor	NN
cord-347298-7kqrl3rv	64	70	necrosis	necrosis	NN
cord-347298-7kqrl3rv	64	71	factor	factor	NN
cord-347298-7kqrl3rv	64	72	;	;	:
cord-347298-7kqrl3rv	64	73	IL	IL	NNP
cord-347298-7kqrl3rv	64	74	,	,	,
cord-347298-7kqrl3rv	64	75	interleukin	interleukin	NN
cord-347298-7kqrl3rv	64	76	;	;	:
cord-347298-7kqrl3rv	64	77	IL1ra	IL1ra	NNP
cord-347298-7kqrl3rv	64	78	,	,	,
cord-347298-7kqrl3rv	64	79	interleukin	interleukin	NN
cord-347298-7kqrl3rv	64	80	1	1	CD
cord-347298-7kqrl3rv	64	81	receptor	receptor	NN
cord-347298-7kqrl3rv	64	82	antagonist	antagonist	NN
cord-347298-7kqrl3rv	64	83	;	;	:
cord-347298-7kqrl3rv	64	84	TGF	TGF	NNP
cord-347298-7kqrl3rv	64	85	,	,	,
cord-347298-7kqrl3rv	64	86	transforming	transform	VBG
cord-347298-7kqrl3rv	64	87	growth	growth	NN
cord-347298-7kqrl3rv	64	88	factor	factor	NN
cord-347298-7kqrl3rv	64	89	;	;	:
cord-347298-7kqrl3rv	64	90	GC	GC	NNP
cord-347298-7kqrl3rv	64	91	,	,	,
cord-347298-7kqrl3rv	64	92	glucocorticoid	glucocorticoid	NN
cord-347298-7kqrl3rv	64	93	;	;	:
cord-347298-7kqrl3rv	64	94	MIF	MIF	NNP
cord-347298-7kqrl3rv	64	95	,	,	,
cord-347298-7kqrl3rv	64	96	macrophage	macrophage	NN
cord-347298-7kqrl3rv	64	97	migration	migration	NN
cord-347298-7kqrl3rv	64	98	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	64	99	factor	factor	NN
cord-347298-7kqrl3rv	64	100	.	.	.
cord-347298-7kqrl3rv	65	1	production	production	NN
cord-347298-7kqrl3rv	65	2	(	(	-LRB-
cord-347298-7kqrl3rv	65	3	Hertzog	Hertzog	NNP
cord-347298-7kqrl3rv	65	4	et	et	NNP
cord-347298-7kqrl3rv	65	5	al	al	NNP
cord-347298-7kqrl3rv	65	6	.	.	.
cord-347298-7kqrl3rv	66	1	2003	2003	CD
cord-347298-7kqrl3rv	66	2	;	;	:
cord-347298-7kqrl3rv	66	3	Malmgaard	Malmgaard	NNP
cord-347298-7kqrl3rv	66	4	2004	2004	CD
cord-347298-7kqrl3rv	66	5	;	;	:
cord-347298-7kqrl3rv	66	6	Nakano	Nakano	NNP
cord-347298-7kqrl3rv	66	7	2004	2004	CD
cord-347298-7kqrl3rv	66	8	)	)	-RRB-
cord-347298-7kqrl3rv	66	9	.	.	.
cord-347298-7kqrl3rv	67	1	The	the	DT
cord-347298-7kqrl3rv	67	2	pattern	pattern	NN
cord-347298-7kqrl3rv	67	3	-	-	HYPH
cord-347298-7kqrl3rv	67	4	recognition	recognition	NN
cord-347298-7kqrl3rv	67	5	receptor	receptor	NN
cord-347298-7kqrl3rv	67	6	family	family	NN
cord-347298-7kqrl3rv	67	7	also	also	RB
cord-347298-7kqrl3rv	67	8	includes	include	VBZ
cord-347298-7kqrl3rv	67	9	the	the	DT
cord-347298-7kqrl3rv	67	10	nucleotide	nucleotide	JJ
cord-347298-7kqrl3rv	67	11	binding	binding	NN
cord-347298-7kqrl3rv	67	12	and	and	CC
cord-347298-7kqrl3rv	67	13	oligomerization	oligomerization	NN
cord-347298-7kqrl3rv	67	14	domain	domain	NN
cord-347298-7kqrl3rv	67	15	(	(	-LRB-
cord-347298-7kqrl3rv	67	16	Nod)-like	Nod)-like	NNP
cord-347298-7kqrl3rv	67	17	receptor	receptor	NN
cord-347298-7kqrl3rv	67	18	(	(	-LRB-
cord-347298-7kqrl3rv	67	19	NLR	NLR	NNP
cord-347298-7kqrl3rv	67	20	)	)	-RRB-
cord-347298-7kqrl3rv	67	21	family	family	NN
cord-347298-7kqrl3rv	67	22	and	and	CC
cord-347298-7kqrl3rv	67	23	the	the	DT
cord-347298-7kqrl3rv	67	24	retinoic	retinoic	JJ
cord-347298-7kqrl3rv	67	25	acid	acid	NN
cord-347298-7kqrl3rv	67	26	-	-	HYPH
cord-347298-7kqrl3rv	67	27	inducible	inducible	JJ
cord-347298-7kqrl3rv	67	28	gene	gene	NN
cord-347298-7kqrl3rv	67	29	(	(	-LRB-
cord-347298-7kqrl3rv	67	30	RIG)-like	rig)-like	NN
cord-347298-7kqrl3rv	67	31	helicases	helicase	NNS
cord-347298-7kqrl3rv	67	32	(	(	-LRB-
cord-347298-7kqrl3rv	67	33	RLHs	RLHs	NNPS
cord-347298-7kqrl3rv	67	34	)	)	-RRB-
cord-347298-7kqrl3rv	68	1	(	(	-LRB-
cord-347298-7kqrl3rv	68	2	Becker	Becker	NNP
cord-347298-7kqrl3rv	68	3	and	and	CC
cord-347298-7kqrl3rv	68	4	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	68	5	2007	2007	CD
cord-347298-7kqrl3rv	68	6	;	;	:
cord-347298-7kqrl3rv	68	7	Thompson	Thompson	NNP
cord-347298-7kqrl3rv	68	8	and	and	CC
cord-347298-7kqrl3rv	68	9	Locarnini	Locarnini	NNP
cord-347298-7kqrl3rv	68	10	2007	2007	CD
cord-347298-7kqrl3rv	68	11	)	)	-RRB-
cord-347298-7kqrl3rv	68	12	.	.	.
cord-347298-7kqrl3rv	69	1	The	the	DT
cord-347298-7kqrl3rv	69	2	NLRs	nlr	NNS
cord-347298-7kqrl3rv	69	3	detect	detect	VBP
cord-347298-7kqrl3rv	69	4	various	various	JJ
cord-347298-7kqrl3rv	69	5	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	69	6	PAMPs	pamp	NNS
cord-347298-7kqrl3rv	69	7	within	within	IN
cord-347298-7kqrl3rv	69	8	the	the	DT
cord-347298-7kqrl3rv	69	9	cytosol	cytosol	NN
cord-347298-7kqrl3rv	69	10	.	.	.
cord-347298-7kqrl3rv	70	1	Some	some	DT
cord-347298-7kqrl3rv	70	2	NLRs	nlr	NNS
cord-347298-7kqrl3rv	70	3	,	,	,
cord-347298-7kqrl3rv	70	4	such	such	JJ
cord-347298-7kqrl3rv	70	5	as	as	IN
cord-347298-7kqrl3rv	70	6	Nod1	Nod1	NNP
cord-347298-7kqrl3rv	70	7	and	and	CC
cord-347298-7kqrl3rv	70	8	Nod2	Nod2	NNP
cord-347298-7kqrl3rv	70	9	,	,	,
cord-347298-7kqrl3rv	70	10	act	act	VBP
cord-347298-7kqrl3rv	70	11	via	via	IN
cord-347298-7kqrl3rv	70	12	NFB	NFB	NNP
cord-347298-7kqrl3rv	70	13	,	,	,
cord-347298-7kqrl3rv	70	14	while	while	IN
cord-347298-7kqrl3rv	70	15	other	other	JJ
cord-347298-7kqrl3rv	70	16	NLRs	nlr	NNS
cord-347298-7kqrl3rv	70	17	work	work	VBP
cord-347298-7kqrl3rv	70	18	through	through	IN
cord-347298-7kqrl3rv	70	19	induction	induction	NN
cord-347298-7kqrl3rv	70	20	of	of	IN
cord-347298-7kqrl3rv	70	21	the	the	DT
cord-347298-7kqrl3rv	70	22	cysteine	cysteine	NN
cord-347298-7kqrl3rv	70	23	protease	protease	NN
cord-347298-7kqrl3rv	70	24	caspase	caspase	NN
cord-347298-7kqrl3rv	70	25	1	1	CD
cord-347298-7kqrl3rv	70	26	,	,	,
cord-347298-7kqrl3rv	70	27	which	which	WDT
cord-347298-7kqrl3rv	70	28	activates	activate	VBZ
cord-347298-7kqrl3rv	70	29	the	the	DT
cord-347298-7kqrl3rv	70	30	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	70	31	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	70	32	IL1	IL1	NNP
cord-347298-7kqrl3rv	70	33	and	and	CC
cord-347298-7kqrl3rv	70	34	IL18	IL18	NNP
cord-347298-7kqrl3rv	70	35	and	and	CC
cord-347298-7kqrl3rv	70	36	initiates	initiate	VBZ
cord-347298-7kqrl3rv	70	37	caspase	caspase	NN
cord-347298-7kqrl3rv	70	38	-	-	HYPH
cord-347298-7kqrl3rv	70	39	mediated	mediate	VBN
cord-347298-7kqrl3rv	70	40	proapoptotic	proapoptotic	JJ
cord-347298-7kqrl3rv	70	41	pathways	pathway	NNS
cord-347298-7kqrl3rv	70	42	within	within	IN
cord-347298-7kqrl3rv	70	43	the	the	DT
cord-347298-7kqrl3rv	70	44	target	target	NN
cord-347298-7kqrl3rv	70	45	cell	cell	NN
cord-347298-7kqrl3rv	70	46	.	.	.
cord-347298-7kqrl3rv	71	1	The	the	DT
cord-347298-7kqrl3rv	71	2	RLHs	rlh	NNS
cord-347298-7kqrl3rv	71	3	,	,	,
cord-347298-7kqrl3rv	71	4	which	which	WDT
cord-347298-7kqrl3rv	71	5	detect	detect	VBP
cord-347298-7kqrl3rv	71	6	the	the	DT
cord-347298-7kqrl3rv	71	7	presence	presence	NN
cord-347298-7kqrl3rv	71	8	of	of	IN
cord-347298-7kqrl3rv	71	9	viral	viral	JJ
cord-347298-7kqrl3rv	71	10	RNA	RNA	NNP
cord-347298-7kqrl3rv	71	11	in	in	IN
cord-347298-7kqrl3rv	71	12	the	the	DT
cord-347298-7kqrl3rv	71	13	cytosol	cytosol	NN
cord-347298-7kqrl3rv	71	14	,	,	,
cord-347298-7kqrl3rv	71	15	activate	activate	VBP
cord-347298-7kqrl3rv	71	16	both	both	DT
cord-347298-7kqrl3rv	71	17	NFB	NFB	NNP
cord-347298-7kqrl3rv	71	18	and	and	CC
cord-347298-7kqrl3rv	71	19	production	production	NN
cord-347298-7kqrl3rv	71	20	of	of	IN
cord-347298-7kqrl3rv	71	21	type	type	NN
cord-347298-7kqrl3rv	71	22	1	1	CD
cord-347298-7kqrl3rv	71	23	IFNs	ifn	NNS
cord-347298-7kqrl3rv	71	24	.	.	.
cord-347298-7kqrl3rv	72	1	Activation	activation	NN
cord-347298-7kqrl3rv	72	2	of	of	IN
cord-347298-7kqrl3rv	72	3	innate	innate	JJ
cord-347298-7kqrl3rv	72	4	immunity	immunity	NN
cord-347298-7kqrl3rv	72	5	leads	lead	VBZ
cord-347298-7kqrl3rv	72	6	to	to	IN
cord-347298-7kqrl3rv	72	7	inflammation	inflammation	NN
cord-347298-7kqrl3rv	72	8	,	,	,
cord-347298-7kqrl3rv	72	9	characterized	characterize	VBN
cord-347298-7kqrl3rv	72	10	by	by	IN
cord-347298-7kqrl3rv	72	11	increased	increase	VBN
cord-347298-7kqrl3rv	72	12	blood	blood	NN
cord-347298-7kqrl3rv	72	13	and	and	CC
cord-347298-7kqrl3rv	72	14	lymphatic	lymphatic	NN
cord-347298-7kqrl3rv	72	15	flow	flow	NN
cord-347298-7kqrl3rv	72	16	within	within	IN
cord-347298-7kqrl3rv	72	17	the	the	DT
cord-347298-7kqrl3rv	72	18	affected	affected	JJ
cord-347298-7kqrl3rv	72	19	tissue	tissue	NN
cord-347298-7kqrl3rv	72	20	and	and	CC
cord-347298-7kqrl3rv	72	21	recruitment	recruitment	NN
cord-347298-7kqrl3rv	72	22	of	of	IN
cord-347298-7kqrl3rv	72	23	immune	immune	JJ
cord-347298-7kqrl3rv	72	24	cells	cell	NNS
cord-347298-7kqrl3rv	72	25	to	to	IN
cord-347298-7kqrl3rv	72	26	the	the	DT
cord-347298-7kqrl3rv	72	27	site	site	NN
cord-347298-7kqrl3rv	72	28	through	through	IN
cord-347298-7kqrl3rv	72	29	production	production	NN
cord-347298-7kqrl3rv	72	30	of	of	IN
cord-347298-7kqrl3rv	72	31	chemokines	chemokine	NNS
cord-347298-7kqrl3rv	72	32	and	and	CC
cord-347298-7kqrl3rv	72	33	expression	expression	NN
cord-347298-7kqrl3rv	72	34	of	of	IN
cord-347298-7kqrl3rv	72	35	vascular	vascular	JJ
cord-347298-7kqrl3rv	72	36	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	72	37	adhesion	adhesion	NN
cord-347298-7kqrl3rv	72	38	molecules	molecule	NNS
cord-347298-7kqrl3rv	72	39	(	(	-LRB-
cord-347298-7kqrl3rv	72	40	Moser	Moser	NNP
cord-347298-7kqrl3rv	72	41	and	and	CC
cord-347298-7kqrl3rv	72	42	Loetscher	Loetscher	NNP
cord-347298-7kqrl3rv	72	43	2001	2001	CD
cord-347298-7kqrl3rv	72	44	;	;	:
cord-347298-7kqrl3rv	72	45	Picker	Picker	NNP
cord-347298-7kqrl3rv	72	46	and	and	CC
cord-347298-7kqrl3rv	72	47	Butcher	Butcher	NNP
cord-347298-7kqrl3rv	72	48	1992	1992	CD
cord-347298-7kqrl3rv	72	49	)	)	-RRB-
cord-347298-7kqrl3rv	72	50	.	.	.
cord-347298-7kqrl3rv	73	1	This	this	DT
cord-347298-7kqrl3rv	73	2	mobilization	mobilization	NN
cord-347298-7kqrl3rv	73	3	of	of	IN
cord-347298-7kqrl3rv	73	4	immune	immune	JJ
cord-347298-7kqrl3rv	73	5	cells	cell	NNS
cord-347298-7kqrl3rv	73	6	is	be	VBZ
cord-347298-7kqrl3rv	73	7	accompanied	accompany	VBN
cord-347298-7kqrl3rv	73	8	by	by	IN
cord-347298-7kqrl3rv	73	9	activation	activation	NN
cord-347298-7kqrl3rv	73	10	of	of	IN
cord-347298-7kqrl3rv	73	11	complement	complement	NN
cord-347298-7kqrl3rv	73	12	,	,	,
cord-347298-7kqrl3rv	73	13	production	production	NN
cord-347298-7kqrl3rv	73	14	of	of	IN
cord-347298-7kqrl3rv	73	15	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	73	16	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	73	17	  	  	_SP
cord-347298-7kqrl3rv	74	1	TLR6	TLR6	NNP
cord-347298-7kqrl3rv	74	2	  	  	_SP
cord-347298-7kqrl3rv	75	1	TLR10	tlr10	CD
cord-347298-7kqrl3rv	76	1	TLR11	TLR11	NNP
cord-347298-7kqrl3rv	77	1	TLR5	TLR5	NNP
cord-347298-7kqrl3rv	77	2	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	77	3	 	 	_SP
cord-347298-7kqrl3rv	78	1	TLR3	TLR3	NNP
cord-347298-7kqrl3rv	78	2	 	 	_SP
cord-347298-7kqrl3rv	79	1	TLR9	TLR9	NNP
cord-347298-7kqrl3rv	79	2	 	 	_SP
cord-347298-7kqrl3rv	80	1	TLR4	TLR4	NNP
cord-347298-7kqrl3rv	80	2	CD14	CD14	NNP
cord-347298-7kqrl3rv	80	3	 	 	_SP
cord-347298-7kqrl3rv	80	4	TLR8	TLR8	NNP
cord-347298-7kqrl3rv	80	5	 	 	_SP
cord-347298-7kqrl3rv	81	1	TLR7	TLR7	NNP
cord-347298-7kqrl3rv	81	2	  	  	_SP
cord-347298-7kqrl3rv	82	1	Cytoplasmic	Cytoplasmic	NNP
cord-347298-7kqrl3rv	82	2	 	 	_SP
cord-347298-7kqrl3rv	82	3	Cell	Cell	NNP
cord-347298-7kqrl3rv	82	4	surface	surface	NN
cord-347298-7kqrl3rv	82	5	  	  	_SP
cord-347298-7kqrl3rv	82	6	CpG	CpG	NNP
cord-347298-7kqrl3rv	82	7	DNA	DNA	NNP
cord-347298-7kqrl3rv	82	8	 	 	_SP
cord-347298-7kqrl3rv	82	9	ssRNA	ssRNA	NNP
cord-347298-7kqrl3rv	82	10	 	 	_SP
cord-347298-7kqrl3rv	82	11	dsRNA	dsrna	NN
cord-347298-7kqrl3rv	82	12	 	 	_SP
cord-347298-7kqrl3rv	83	1	Lipoproteins	lipoprotein	NNS
cord-347298-7kqrl3rv	83	2	 	 	_SP
cord-347298-7kqrl3rv	84	1	LPS	LPS	NNP
cord-347298-7kqrl3rv	84	2	 	 	_SP
cord-347298-7kqrl3rv	84	3	Flagellin	Flagellin	NNP
cord-347298-7kqrl3rv	84	4	/	/	SYM
cord-347298-7kqrl3rv	84	5	Profilin	Profilin	NNP
cord-347298-7kqrl3rv	84	6	 	 	_SP
cord-347298-7kqrl3rv	84	7	?	?	.
cord-347298-7kqrl3rv	84	8	  	  	_SP
cord-347298-7kqrl3rv	85	1	IRF3	IRF3	NNP
cord-347298-7kqrl3rv	85	2	 	 	_SP
cord-347298-7kqrl3rv	86	1	NFkB	nfkb	UH
cord-347298-7kqrl3rv	86	2	 	 	_SP
cord-347298-7kqrl3rv	87	1	AP1	AP1	NNP
cord-347298-7kqrl3rv	87	2	  	  	_SP
cord-347298-7kqrl3rv	87	3	MAP	MAP	NNP
cord-347298-7kqrl3rv	87	4	kinases	kinase	NNS
cord-347298-7kqrl3rv	87	5	  	  	_SP
cord-347298-7kqrl3rv	88	1	IL1α	IL1α	NNP
cord-347298-7kqrl3rv	88	2	,	,	,
cord-347298-7kqrl3rv	88	3	TNFα	TNFα	NNP
cord-347298-7kqrl3rv	88	4	,	,	,
cord-347298-7kqrl3rv	88	5	IL6	il6	NN
cord-347298-7kqrl3rv	88	6	,	,	,
cord-347298-7kqrl3rv	88	7	iNOS	iNOS	NNP
cord-347298-7kqrl3rv	88	8	,	,	,
cord-347298-7kqrl3rv	88	9	activin	activin	NNP
cord-347298-7kqrl3rv	88	10	A	A	NNP
cord-347298-7kqrl3rv	88	11	,	,	,
cord-347298-7kqrl3rv	88	12	IL10	IL10	NNP
cord-347298-7kqrl3rv	88	13	,	,	,
cord-347298-7kqrl3rv	88	14	IL12	IL12	NNP
cord-347298-7kqrl3rv	88	15	,	,	,
cord-347298-7kqrl3rv	88	16	COX2	COX2	NNP
cord-347298-7kqrl3rv	88	17	,	,	,
cord-347298-7kqrl3rv	88	18	IFNγ	IFNγ	NNS
cord-347298-7kqrl3rv	88	19	  	  	_SP
cord-347298-7kqrl3rv	88	20	Mal	Mal	NNP
cord-347298-7kqrl3rv	88	21	 	 	_SP
cord-347298-7kqrl3rv	89	1	TRAM	tram	NN
cord-347298-7kqrl3rv	89	2	  	  	_SP
cord-347298-7kqrl3rv	89	3	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	89	4	 	 	_SP
cord-347298-7kqrl3rv	89	5	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	89	6	  	  	_SP
cord-347298-7kqrl3rv	90	1	TLR1	TLR1	NNP
cord-347298-7kqrl3rv	90	2	  	  	_SP
cord-347298-7kqrl3rv	91	1	Apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	91	2	 	 	_SP
cord-347298-7kqrl3rv	92	1	IRF1,5,7	IRF1,5,7	NNP
cord-347298-7kqrl3rv	92	2	  	  	_SP
cord-347298-7kqrl3rv	92	3	IFNα	IFNα	NNP
cord-347298-7kqrl3rv	92	4	,	,	,
cord-347298-7kqrl3rv	92	5	IFNβ	IFNβ	NNS
cord-347298-7kqrl3rv	92	6	,	,	,
cord-347298-7kqrl3rv	92	7	TNFα	TNFα	NNS
cord-347298-7kqrl3rv	92	8	  	  	_SP
cord-347298-7kqrl3rv	92	9	MyD88	MyD88	NNS
cord-347298-7kqrl3rv	92	10	  	  	_SP
cord-347298-7kqrl3rv	93	1	TRAF6	TRAF6	NNP
cord-347298-7kqrl3rv	93	2	 	 	_SP
cord-347298-7kqrl3rv	94	1	TRAF3	TRAF3	NNP
cord-347298-7kqrl3rv	94	2	 	 	_SP
cord-347298-7kqrl3rv	95	1	TRAF3,6	TRAF3,6	NNP
cord-347298-7kqrl3rv	96	1	MyD88	MyD88	NNP
cord-347298-7kqrl3rv	96	2	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	96	3	Figure	figure	NN
cord-347298-7kqrl3rv	96	4	2	2	CD
cord-347298-7kqrl3rv	97	1	The	the	DT
cord-347298-7kqrl3rv	97	2	Toll	Toll	NNP
cord-347298-7kqrl3rv	97	3	-	-	HYPH
cord-347298-7kqrl3rv	97	4	like	like	JJ
cord-347298-7kqrl3rv	97	5	receptors	receptor	NNS
cord-347298-7kqrl3rv	97	6	:	:	:
cord-347298-7kqrl3rv	97	7	major	major	JJ
cord-347298-7kqrl3rv	97	8	pathogenic	pathogenic	JJ
cord-347298-7kqrl3rv	97	9	ligands	ligand	NNS
cord-347298-7kqrl3rv	97	10	,	,	,
cord-347298-7kqrl3rv	97	11	adaptor	adaptor	NN
cord-347298-7kqrl3rv	97	12	proteins	protein	NNS
cord-347298-7kqrl3rv	97	13	,	,	,
cord-347298-7kqrl3rv	97	14	signaling	signal	VBG
cord-347298-7kqrl3rv	97	15	,	,	,
cord-347298-7kqrl3rv	97	16	and	and	CC
cord-347298-7kqrl3rv	97	17	cytokine	cytokine	NN
cord-347298-7kqrl3rv	97	18	production	production	NN
cord-347298-7kqrl3rv	97	19	.	.	.
cord-347298-7kqrl3rv	98	1	There	there	EX
cord-347298-7kqrl3rv	98	2	are	be	VBP
cord-347298-7kqrl3rv	98	3	10	10	CD
cord-347298-7kqrl3rv	98	4	active	active	JJ
cord-347298-7kqrl3rv	98	5	human	human	JJ
cord-347298-7kqrl3rv	98	6	Toll	toll	NN
cord-347298-7kqrl3rv	98	7	-	-	HYPH
cord-347298-7kqrl3rv	98	8	like	like	JJ
cord-347298-7kqrl3rv	98	9	receptors	receptor	NNS
cord-347298-7kqrl3rv	98	10	(	(	-LRB-
cord-347298-7kqrl3rv	98	11	TLR1	TLR1	NNP
cord-347298-7kqrl3rv	98	12	-	-	HYPH
cord-347298-7kqrl3rv	98	13	10	10	CD
cord-347298-7kqrl3rv	98	14	)	)	-RRB-
cord-347298-7kqrl3rv	98	15	.	.	.
cord-347298-7kqrl3rv	99	1	TLR11	TLR11	NNP
cord-347298-7kqrl3rv	99	2	-	-	HYPH
cord-347298-7kqrl3rv	99	3	13	13	CD
cord-347298-7kqrl3rv	99	4	are	be	VBP
cord-347298-7kqrl3rv	99	5	present	present	JJ
cord-347298-7kqrl3rv	99	6	in	in	IN
cord-347298-7kqrl3rv	99	7	rodents	rodent	NNS
cord-347298-7kqrl3rv	99	8	,	,	,
cord-347298-7kqrl3rv	99	9	and	and	CC
cord-347298-7kqrl3rv	99	10	TLR11	TLR11	NNP
cord-347298-7kqrl3rv	99	11	is	be	VBZ
cord-347298-7kqrl3rv	99	12	specific	specific	JJ
cord-347298-7kqrl3rv	99	13	to	to	IN
cord-347298-7kqrl3rv	99	14	the	the	DT
cord-347298-7kqrl3rv	99	15	urogenital	urogenital	JJ
cord-347298-7kqrl3rv	99	16	tract	tract	NN
cord-347298-7kqrl3rv	99	17	.	.	.
cord-347298-7kqrl3rv	100	1	The	the	DT
cord-347298-7kqrl3rv	100	2	TLRs	tlr	NNS
cord-347298-7kqrl3rv	100	3	respond	respond	VBP
cord-347298-7kqrl3rv	100	4	to	to	IN
cord-347298-7kqrl3rv	100	5	a	a	DT
cord-347298-7kqrl3rv	100	6	variety	variety	NN
cord-347298-7kqrl3rv	100	7	of	of	IN
cord-347298-7kqrl3rv	100	8	pathogen	pathogen	NN
cord-347298-7kqrl3rv	100	9	-	-	HYPH
cord-347298-7kqrl3rv	100	10	related	relate	VBN
cord-347298-7kqrl3rv	100	11	molecules	molecule	NNS
cord-347298-7kqrl3rv	100	12	,	,	,
cord-347298-7kqrl3rv	100	13	usually	usually	RB
cord-347298-7kqrl3rv	100	14	forming	form	VBG
cord-347298-7kqrl3rv	100	15	homo	homo	NN
cord-347298-7kqrl3rv	100	16	-	-	HYPH
cord-347298-7kqrl3rv	100	17	or	or	CC
cord-347298-7kqrl3rv	100	18	heterodimers	heterodimer	NNS
cord-347298-7kqrl3rv	100	19	during	during	IN
cord-347298-7kqrl3rv	100	20	signaling	signal	VBG
cord-347298-7kqrl3rv	100	21	:	:	:
cord-347298-7kqrl3rv	100	22	for	for	IN
cord-347298-7kqrl3rv	100	23	example	example	NN
cord-347298-7kqrl3rv	100	24	,	,	,
cord-347298-7kqrl3rv	100	25	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	100	26	can	can	MD
cord-347298-7kqrl3rv	100	27	self	self	NN
cord-347298-7kqrl3rv	100	28	-	-	HYPH
cord-347298-7kqrl3rv	100	29	associate	associate	VB
cord-347298-7kqrl3rv	100	30	or	or	CC
cord-347298-7kqrl3rv	100	31	combine	combine	VBP
cord-347298-7kqrl3rv	100	32	with	with	IN
cord-347298-7kqrl3rv	100	33	either	either	CC
cord-347298-7kqrl3rv	100	34	TLR1	TLR1	NNP
cord-347298-7kqrl3rv	100	35	or	or	CC
cord-347298-7kqrl3rv	100	36	TLR6	TLR6	NNP
cord-347298-7kqrl3rv	100	37	to	to	TO
cord-347298-7kqrl3rv	100	38	mediate	mediate	VB
cord-347298-7kqrl3rv	100	39	responses	response	NNS
cord-347298-7kqrl3rv	100	40	to	to	IN
cord-347298-7kqrl3rv	100	41	various	various	JJ
cord-347298-7kqrl3rv	100	42	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	100	43	lipoprotein	lipoprotein	NN
cord-347298-7kqrl3rv	100	44	classes	class	NNS
cord-347298-7kqrl3rv	100	45	.	.	.
cord-347298-7kqrl3rv	101	1	TLR4	TLR4	NNP
cord-347298-7kqrl3rv	101	2	forms	form	VBZ
cord-347298-7kqrl3rv	101	3	a	a	DT
cord-347298-7kqrl3rv	101	4	complex	complex	NN
cord-347298-7kqrl3rv	101	5	with	with	IN
cord-347298-7kqrl3rv	101	6	the	the	DT
cord-347298-7kqrl3rv	101	7	receptor	receptor	NN
cord-347298-7kqrl3rv	101	8	cofactor	cofactor	NN
cord-347298-7kqrl3rv	101	9	CD14	CD14	NNP
cord-347298-7kqrl3rv	101	10	,	,	,
cord-347298-7kqrl3rv	101	11	to	to	TO
cord-347298-7kqrl3rv	101	12	facilitate	facilitate	VB
cord-347298-7kqrl3rv	101	13	binding	binding	NN
cord-347298-7kqrl3rv	101	14	of	of	IN
cord-347298-7kqrl3rv	101	15	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	101	16	lipopolysaccharide	lipopolysaccharide	NN
cord-347298-7kqrl3rv	101	17	(	(	-LRB-
cord-347298-7kqrl3rv	101	18	LPS	LPS	NNP
cord-347298-7kqrl3rv	101	19	)	)	-RRB-
cord-347298-7kqrl3rv	101	20	.	.	.
cord-347298-7kqrl3rv	102	1	The	the	DT
cord-347298-7kqrl3rv	102	2	TLRs	tlr	NNS
cord-347298-7kqrl3rv	102	3	can	can	MD
cord-347298-7kqrl3rv	102	4	be	be	VB
cord-347298-7kqrl3rv	102	5	subdivided	subdivide	VBN
cord-347298-7kqrl3rv	102	6	into	into	IN
cord-347298-7kqrl3rv	102	7	cell	cell	NN
cord-347298-7kqrl3rv	102	8	surface	surface	NN
cord-347298-7kqrl3rv	102	9	receptors	receptor	NNS
cord-347298-7kqrl3rv	102	10	,	,	,
cord-347298-7kqrl3rv	102	11	which	which	WDT
cord-347298-7kqrl3rv	102	12	largely	largely	RB
cord-347298-7kqrl3rv	102	13	respond	respond	VBP
cord-347298-7kqrl3rv	102	14	to	to	IN
cord-347298-7kqrl3rv	102	15	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	102	16	proteins	protein	NNS
cord-347298-7kqrl3rv	102	17	,	,	,
cord-347298-7kqrl3rv	102	18	lipoproteins	lipoprotein	NNS
cord-347298-7kqrl3rv	102	19	,	,	,
cord-347298-7kqrl3rv	102	20	and	and	CC
cord-347298-7kqrl3rv	102	21	lipopolysaccharides	lipopolysaccharides	NNP
cord-347298-7kqrl3rv	102	22	,	,	,
cord-347298-7kqrl3rv	102	23	and	and	CC
cord-347298-7kqrl3rv	102	24	intracytoplasmic	intracytoplasmic	JJ
cord-347298-7kqrl3rv	102	25	receptors	receptor	NNS
cord-347298-7kqrl3rv	102	26	,	,	,
cord-347298-7kqrl3rv	102	27	which	which	WDT
cord-347298-7kqrl3rv	102	28	recognize	recognize	VBP
cord-347298-7kqrl3rv	102	29	single	single	RB
cord-347298-7kqrl3rv	102	30	-	-	HYPH
cord-347298-7kqrl3rv	102	31	stranded	stranded	JJ
cord-347298-7kqrl3rv	102	32	and	and	CC
cord-347298-7kqrl3rv	102	33	double	double	RB
cord-347298-7kqrl3rv	102	34	-	-	HYPH
cord-347298-7kqrl3rv	102	35	stranded	strand	VBN
cord-347298-7kqrl3rv	102	36	RNA	RNA	NNP
cord-347298-7kqrl3rv	102	37	(	(	-LRB-
cord-347298-7kqrl3rv	102	38	ssRNA	ssrna	NN
cord-347298-7kqrl3rv	102	39	and	and	CC
cord-347298-7kqrl3rv	102	40	dsRNA	dsrna	NN
cord-347298-7kqrl3rv	102	41	)	)	-RRB-
cord-347298-7kqrl3rv	102	42	and	and	CC
cord-347298-7kqrl3rv	102	43	CpG	CpG	NNP
cord-347298-7kqrl3rv	102	44	-	-	HYPH
cord-347298-7kqrl3rv	102	45	containing	contain	VBG
cord-347298-7kqrl3rv	102	46	DNA	dna	NN
cord-347298-7kqrl3rv	102	47	of	of	IN
cord-347298-7kqrl3rv	102	48	viral	viral	JJ
cord-347298-7kqrl3rv	102	49	or	or	CC
cord-347298-7kqrl3rv	102	50	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	102	51	origin	origin	NN
cord-347298-7kqrl3rv	102	52	.	.	.
cord-347298-7kqrl3rv	103	1	Most	Most	JJS
cord-347298-7kqrl3rv	103	2	TLRs	tlr	NNS
cord-347298-7kqrl3rv	103	3	signal	signal	NN
cord-347298-7kqrl3rv	103	4	via	via	IN
cord-347298-7kqrl3rv	103	5	the	the	DT
cord-347298-7kqrl3rv	103	6	adaptor	adaptor	NN
cord-347298-7kqrl3rv	103	7	protein	protein	NN
cord-347298-7kqrl3rv	103	8	MyD88	MyD88	NNS
cord-347298-7kqrl3rv	103	9	(	(	-LRB-
cord-347298-7kqrl3rv	103	10	myeloid	myeloid	JJ
cord-347298-7kqrl3rv	103	11	differentiation	differentiation	NN
cord-347298-7kqrl3rv	103	12	primary	primary	JJ
cord-347298-7kqrl3rv	103	13	response	response	NN
cord-347298-7kqrl3rv	103	14	protein	protein	NN
cord-347298-7kqrl3rv	103	15	88	88	CD
cord-347298-7kqrl3rv	103	16	)	)	-RRB-
cord-347298-7kqrl3rv	103	17	,	,	,
cord-347298-7kqrl3rv	103	18	except	except	IN
cord-347298-7kqrl3rv	103	19	TLR3	TLR3	NNP
cord-347298-7kqrl3rv	103	20	,	,	,
cord-347298-7kqrl3rv	103	21	which	which	WDT
cord-347298-7kqrl3rv	103	22	acts	act	VBZ
cord-347298-7kqrl3rv	103	23	through	through	IN
cord-347298-7kqrl3rv	103	24	the	the	DT
cord-347298-7kqrl3rv	103	25	adaptor	adaptor	NN
cord-347298-7kqrl3rv	103	26	protein	protein	NN
cord-347298-7kqrl3rv	103	27	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	104	1	(	(	-LRB-
cord-347298-7kqrl3rv	104	2	TIR	TIR	NNP
cord-347298-7kqrl3rv	104	3	domaincontaining	domaincontaining	NN
cord-347298-7kqrl3rv	104	4	adaptor	adaptor	NN
cord-347298-7kqrl3rv	104	5	protein	protein	NN
cord-347298-7kqrl3rv	104	6	inducing	induce	VBG
cord-347298-7kqrl3rv	104	7	interferon	interferon	NN
cord-347298-7kqrl3rv	104	8	)	)	-RRB-
cord-347298-7kqrl3rv	104	9	.	.	.
cord-347298-7kqrl3rv	105	1	Uniquely	uniquely	RB
cord-347298-7kqrl3rv	105	2	,	,	,
cord-347298-7kqrl3rv	105	3	TLR4	TLR4	NNP
cord-347298-7kqrl3rv	105	4	can	can	MD
cord-347298-7kqrl3rv	105	5	interact	interact	VB
cord-347298-7kqrl3rv	105	6	with	with	IN
cord-347298-7kqrl3rv	105	7	either	either	CC
cord-347298-7kqrl3rv	105	8	MyD88	MyD88	NNS
cord-347298-7kqrl3rv	105	9	or	or	CC
cord-347298-7kqrl3rv	105	10	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	105	11	,	,	,
cord-347298-7kqrl3rv	105	12	through	through	IN
cord-347298-7kqrl3rv	105	13	engagement	engagement	NN
cord-347298-7kqrl3rv	105	14	of	of	IN
cord-347298-7kqrl3rv	105	15	the	the	DT
cord-347298-7kqrl3rv	105	16	adaptor	adaptor	NN
cord-347298-7kqrl3rv	105	17	proteins	protein	NNS
cord-347298-7kqrl3rv	106	1	Mal	mal	JJ
cord-347298-7kqrl3rv	106	2	(	(	-LRB-
cord-347298-7kqrl3rv	106	3	MyD88	myd88	JJ
cord-347298-7kqrl3rv	106	4	adaptor	adaptor	NN
cord-347298-7kqrl3rv	106	5	-	-	HYPH
cord-347298-7kqrl3rv	106	6	like	like	JJ
cord-347298-7kqrl3rv	106	7	)	)	-RRB-
cord-347298-7kqrl3rv	106	8	or	or	CC
cord-347298-7kqrl3rv	106	9	TRAM	tram	NN
cord-347298-7kqrl3rv	107	1	(	(	-LRB-
cord-347298-7kqrl3rv	107	2	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	107	3	-	-	HYPH
cord-347298-7kqrl3rv	107	4	related	relate	VBN
cord-347298-7kqrl3rv	107	5	adaptor	adaptor	NN
cord-347298-7kqrl3rv	107	6	molecule	molecule	NN
cord-347298-7kqrl3rv	107	7	)	)	-RRB-
cord-347298-7kqrl3rv	107	8	.	.	.
cord-347298-7kqrl3rv	108	1	Downstream	downstream	JJ
cord-347298-7kqrl3rv	108	2	signaling	signaling	NN
cord-347298-7kqrl3rv	108	3	involves	involve	VBZ
cord-347298-7kqrl3rv	108	4	the	the	DT
cord-347298-7kqrl3rv	108	5	tumor	tumor	NN
cord-347298-7kqrl3rv	108	6	necrosis	necrosis	NN
cord-347298-7kqrl3rv	108	7	factor	factor	NN
cord-347298-7kqrl3rv	108	8	receptor	receptor	NN
cord-347298-7kqrl3rv	108	9	-	-	HYPH
cord-347298-7kqrl3rv	108	10	associated	associate	VBN
cord-347298-7kqrl3rv	108	11	factors	factor	NNS
cord-347298-7kqrl3rv	108	12	3	3	CD
cord-347298-7kqrl3rv	108	13	and	and	CC
cord-347298-7kqrl3rv	108	14	6	6	CD
cord-347298-7kqrl3rv	108	15	(	(	-LRB-
cord-347298-7kqrl3rv	108	16	TRAF3	TRAF3	NNP
cord-347298-7kqrl3rv	108	17	and	and	CC
cord-347298-7kqrl3rv	108	18	TRAF6	TRAF6	NNP
cord-347298-7kqrl3rv	108	19	)	)	-RRB-
cord-347298-7kqrl3rv	108	20	,	,	,
cord-347298-7kqrl3rv	108	21	activation	activation	NN
cord-347298-7kqrl3rv	108	22	of	of	IN
cord-347298-7kqrl3rv	108	23	the	the	DT
cord-347298-7kqrl3rv	108	24	transcription	transcription	NN
cord-347298-7kqrl3rv	108	25	factors	factor	NNS
cord-347298-7kqrl3rv	108	26	nuclear	nuclear	JJ
cord-347298-7kqrl3rv	108	27	factor	factor	NN
cord-347298-7kqrl3rv	108	28	kappaB	kappaB	NNP
cord-347298-7kqrl3rv	108	29	(	(	-LRB-
cord-347298-7kqrl3rv	108	30	NFB	NFB	NNP
cord-347298-7kqrl3rv	108	31	)	)	-RRB-
cord-347298-7kqrl3rv	108	32	and	and	CC
cord-347298-7kqrl3rv	108	33	interferon	interferon	NN
cord-347298-7kqrl3rv	108	34	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	108	35	factor	factor	NN
cord-347298-7kqrl3rv	108	36	1	1	CD
cord-347298-7kqrl3rv	108	37	(	(	-LRB-
cord-347298-7kqrl3rv	108	38	IRF1	IRF1	NNP
cord-347298-7kqrl3rv	108	39	)	)	-RRB-
cord-347298-7kqrl3rv	108	40	,	,	,
cord-347298-7kqrl3rv	108	41	or	or	CC
cord-347298-7kqrl3rv	108	42	activation	activation	NN
cord-347298-7kqrl3rv	108	43	of	of	IN
cord-347298-7kqrl3rv	108	44	the	the	DT
cord-347298-7kqrl3rv	108	45	mitogenactivated	mitogenactivated	JJ
cord-347298-7kqrl3rv	108	46	protein	protein	NN
cord-347298-7kqrl3rv	108	47	kinases	kinases	NNP
cord-347298-7kqrl3rv	108	48	(	(	-LRB-
cord-347298-7kqrl3rv	108	49	MAP	MAP	NNP
cord-347298-7kqrl3rv	108	50	kinases	kinase	NNS
cord-347298-7kqrl3rv	108	51	)	)	-RRB-
cord-347298-7kqrl3rv	109	1	Jun	Jun	NNP
cord-347298-7kqrl3rv	109	2	N	N	NNP
cord-347298-7kqrl3rv	109	3	-	-	HYPH
cord-347298-7kqrl3rv	109	4	terminal	terminal	NN
cord-347298-7kqrl3rv	109	5	kinase	kinase	NN
cord-347298-7kqrl3rv	109	6	(	(	-LRB-
cord-347298-7kqrl3rv	109	7	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	109	8	)	)	-RRB-
cord-347298-7kqrl3rv	109	9	and	and	CC
cord-347298-7kqrl3rv	109	10	p38	p38	CD
cord-347298-7kqrl3rv	109	11	to	to	TO
cord-347298-7kqrl3rv	109	12	produce	produce	VB
cord-347298-7kqrl3rv	109	13	the	the	DT
cord-347298-7kqrl3rv	109	14	Fos	Fos	NNP
cord-347298-7kqrl3rv	109	15	/	/	SYM
cord-347298-7kqrl3rv	109	16	Jun	Jun	NNP
cord-347298-7kqrl3rv	109	17	transcription	transcription	NN
cord-347298-7kqrl3rv	109	18	factor	factor	NN
cord-347298-7kqrl3rv	109	19	activated	activate	VBD
cord-347298-7kqrl3rv	109	20	protein	protein	NN
cord-347298-7kqrl3rv	109	21	1	1	CD
cord-347298-7kqrl3rv	109	22	(	(	-LRB-
cord-347298-7kqrl3rv	109	23	AP1	AP1	NNP
cord-347298-7kqrl3rv	109	24	)	)	-RRB-
cord-347298-7kqrl3rv	109	25	.	.	.
cord-347298-7kqrl3rv	110	1	These	these	DT
cord-347298-7kqrl3rv	110	2	transcription	transcription	NN
cord-347298-7kqrl3rv	110	3	factors	factor	NNS
cord-347298-7kqrl3rv	110	4	interact	interact	VBP
cord-347298-7kqrl3rv	110	5	to	to	TO
cord-347298-7kqrl3rv	110	6	induce	induce	VB
cord-347298-7kqrl3rv	110	7	the	the	DT
cord-347298-7kqrl3rv	110	8	expression	expression	NN
cord-347298-7kqrl3rv	110	9	of	of	IN
cord-347298-7kqrl3rv	110	10	multiple	multiple	JJ
cord-347298-7kqrl3rv	110	11	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	110	12	genes	gene	NNS
cord-347298-7kqrl3rv	110	13	,	,	,
cord-347298-7kqrl3rv	110	14	including	include	VBG
cord-347298-7kqrl3rv	110	15	interleukin	interleukin	NN
cord-347298-7kqrl3rv	110	16	(	(	-LRB-
cord-347298-7kqrl3rv	110	17	IL	IL	NNP
cord-347298-7kqrl3rv	110	18	)	)	-RRB-
cord-347298-7kqrl3rv	110	19	1	1	CD
cord-347298-7kqrl3rv	110	20	,	,	,
cord-347298-7kqrl3rv	110	21	tumor	tumor	NN
cord-347298-7kqrl3rv	110	22	necrosis	necrosis	NN
cord-347298-7kqrl3rv	110	23	factor	factor	NN
cord-347298-7kqrl3rv	110	24	(	(	-LRB-
cord-347298-7kqrl3rv	110	25	TNF	TNF	NNP
cord-347298-7kqrl3rv	110	26	)	)	-RRB-
cord-347298-7kqrl3rv	110	27	,	,	,
cord-347298-7kqrl3rv	110	28	inducible	inducible	JJ
cord-347298-7kqrl3rv	110	29	nitric	nitric	NN
cord-347298-7kqrl3rv	110	30	oxide	oxide	NN
cord-347298-7kqrl3rv	110	31	(	(	-LRB-
cord-347298-7kqrl3rv	110	32	iNOS	inos	NN
cord-347298-7kqrl3rv	110	33	)	)	-RRB-
cord-347298-7kqrl3rv	110	34	,	,	,
cord-347298-7kqrl3rv	110	35	cyclooxygenase	cyclooxygenase	JJ
cord-347298-7kqrl3rv	110	36	2	2	CD
cord-347298-7kqrl3rv	110	37	(	(	-LRB-
cord-347298-7kqrl3rv	110	38	COX2	COX2	NNP
cord-347298-7kqrl3rv	110	39	)	)	-RRB-
cord-347298-7kqrl3rv	110	40	,	,	,
cord-347298-7kqrl3rv	110	41	and	and	CC
cord-347298-7kqrl3rv	110	42	interferon	interferon	NN
cord-347298-7kqrl3rv	110	43	(	(	-LRB-
cord-347298-7kqrl3rv	110	44	IFN	IFN	NNP
cord-347298-7kqrl3rv	110	45	)	)	-RRB-
cord-347298-7kqrl3rv	110	46	,	,	,
cord-347298-7kqrl3rv	110	47	or	or	CC
cord-347298-7kqrl3rv	110	48	the	the	DT
cord-347298-7kqrl3rv	110	49	type	type	NN
cord-347298-7kqrl3rv	110	50	1	1	CD
cord-347298-7kqrl3rv	110	51	interferons	interferon	NNS
cord-347298-7kqrl3rv	110	52	(	(	-LRB-
cord-347298-7kqrl3rv	110	53	IFN	IFN	NNP
cord-347298-7kqrl3rv	110	54	,	,	,
cord-347298-7kqrl3rv	110	55	IFN	IFN	NNP
cord-347298-7kqrl3rv	110	56	)	)	-RRB-
cord-347298-7kqrl3rv	110	57	and	and	CC
cord-347298-7kqrl3rv	110	58	TNF	TNF	NNP
cord-347298-7kqrl3rv	110	59	.	.	.
cord-347298-7kqrl3rv	111	1	Note	note	VB
cord-347298-7kqrl3rv	111	2	that	that	IN
cord-347298-7kqrl3rv	111	3	many	many	JJ
cord-347298-7kqrl3rv	111	4	details	detail	NNS
cord-347298-7kqrl3rv	111	5	of	of	IN
cord-347298-7kqrl3rv	111	6	the	the	DT
cord-347298-7kqrl3rv	111	7	signaling	signal	VBG
cord-347298-7kqrl3rv	111	8	pathways	pathway	NNS
cord-347298-7kqrl3rv	111	9	have	have	VBP
cord-347298-7kqrl3rv	111	10	been	be	VBN
cord-347298-7kqrl3rv	111	11	omitted	omit	VBN
cord-347298-7kqrl3rv	111	12	or	or	CC
cord-347298-7kqrl3rv	111	13	truncated	truncate	VBN
cord-347298-7kqrl3rv	111	14	for	for	IN
cord-347298-7kqrl3rv	111	15	the	the	DT
cord-347298-7kqrl3rv	111	16	sake	sake	NN
cord-347298-7kqrl3rv	111	17	of	of	IN
cord-347298-7kqrl3rv	111	18	simplicity	simplicity	NN
cord-347298-7kqrl3rv	111	19	.	.	.
cord-347298-7kqrl3rv	112	1	and	and	CC
cord-347298-7kqrl3rv	112	2	acute	acute	JJ
cord-347298-7kqrl3rv	112	3	-	-	HYPH
cord-347298-7kqrl3rv	112	4	phase	phase	NN
cord-347298-7kqrl3rv	112	5	proteins	protein	NNS
cord-347298-7kqrl3rv	112	6	,	,	,
cord-347298-7kqrl3rv	112	7	and	and	CC
cord-347298-7kqrl3rv	112	8	stimulation	stimulation	NN
cord-347298-7kqrl3rv	112	9	of	of	IN
cord-347298-7kqrl3rv	112	10	phagocytosis	phagocytosis	NN
cord-347298-7kqrl3rv	112	11	and	and	CC
cord-347298-7kqrl3rv	112	12	killing	killing	NN
cord-347298-7kqrl3rv	112	13	of	of	IN
cord-347298-7kqrl3rv	112	14	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	112	15	and	and	CC
cord-347298-7kqrl3rv	112	16	infected	infected	JJ
cord-347298-7kqrl3rv	112	17	cells	cell	NNS
cord-347298-7kqrl3rv	112	18	by	by	IN
cord-347298-7kqrl3rv	112	19	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	112	20	,	,	,
cord-347298-7kqrl3rv	112	21	PMNs	PMNs	NNP
cord-347298-7kqrl3rv	112	22	,	,	,
cord-347298-7kqrl3rv	112	23	and	and	CC
cord-347298-7kqrl3rv	112	24	NK	NK	NNP
cord-347298-7kqrl3rv	112	25	cells	cell	NNS
cord-347298-7kqrl3rv	112	26	,	,	,
cord-347298-7kqrl3rv	112	27	through	through	IN
cord-347298-7kqrl3rv	112	28	production	production	NN
cord-347298-7kqrl3rv	112	29	of	of	IN
cord-347298-7kqrl3rv	112	30	proteases	protease	NNS
cord-347298-7kqrl3rv	112	31	and	and	CC
cord-347298-7kqrl3rv	112	32	other	other	JJ
cord-347298-7kqrl3rv	112	33	lytic	lytic	JJ
cord-347298-7kqrl3rv	112	34	proteins	protein	NNS
cord-347298-7kqrl3rv	112	35	,	,	,
cord-347298-7kqrl3rv	112	36	and	and	CC
cord-347298-7kqrl3rv	112	37	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	112	38	reactive	reactive	JJ
cord-347298-7kqrl3rv	112	39	oxygen	oxygen	NN
cord-347298-7kqrl3rv	112	40	species	specie	NNS
cord-347298-7kqrl3rv	112	41	(	(	-LRB-
cord-347298-7kqrl3rv	112	42	ROS	ROS	NNP
cord-347298-7kqrl3rv	112	43	)	)	-RRB-
cord-347298-7kqrl3rv	112	44	and	and	CC
cord-347298-7kqrl3rv	112	45	induction	induction	NN
cord-347298-7kqrl3rv	112	46	of	of	IN
cord-347298-7kqrl3rv	112	47	apoptotic	apoptotic	JJ
cord-347298-7kqrl3rv	112	48	pathways	pathway	NNS
cord-347298-7kqrl3rv	112	49	(	(	-LRB-
cord-347298-7kqrl3rv	112	50	Rosenberg	Rosenberg	NNP
cord-347298-7kqrl3rv	112	51	and	and	CC
cord-347298-7kqrl3rv	112	52	Gallin	Gallin	NNP
cord-347298-7kqrl3rv	112	53	2003	2003	CD
cord-347298-7kqrl3rv	112	54	)	)	-RRB-
cord-347298-7kqrl3rv	112	55	.	.	.
cord-347298-7kqrl3rv	113	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	113	2	,	,	,
cord-347298-7kqrl3rv	113	3	activation	activation	NN
cord-347298-7kqrl3rv	113	4	of	of	IN
cord-347298-7kqrl3rv	113	5	innate	innate	JJ
cord-347298-7kqrl3rv	113	6	immunity	immunity	NN
cord-347298-7kqrl3rv	113	7	is	be	VBZ
cord-347298-7kqrl3rv	113	8	responsible	responsible	JJ
cord-347298-7kqrl3rv	113	9	for	for	IN
cord-347298-7kqrl3rv	113	10	initiation	initiation	NN
cord-347298-7kqrl3rv	113	11	of	of	IN
cord-347298-7kqrl3rv	113	12	the	the	DT
cord-347298-7kqrl3rv	113	13	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	113	14	immune	immune	JJ
cord-347298-7kqrl3rv	113	15	response	response	NN
cord-347298-7kqrl3rv	113	16	,	,	,
cord-347298-7kqrl3rv	113	17	through	through	IN
cord-347298-7kqrl3rv	113	18	production	production	NN
cord-347298-7kqrl3rv	113	19	of	of	IN
cord-347298-7kqrl3rv	113	20	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	113	21	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	113	22	and	and	CC
cord-347298-7kqrl3rv	113	23	stimulation	stimulation	NN
cord-347298-7kqrl3rv	113	24	of	of	IN
cord-347298-7kqrl3rv	113	25	the	the	DT
cord-347298-7kqrl3rv	113	26	antigen	antigen	NN
cord-347298-7kqrl3rv	113	27	-	-	HYPH
cord-347298-7kqrl3rv	113	28	presenting	present	VBG
cord-347298-7kqrl3rv	113	29	cell	cell	NN
cord-347298-7kqrl3rv	113	30	(	(	-LRB-
cord-347298-7kqrl3rv	113	31	APC	APC	NNP
cord-347298-7kqrl3rv	113	32	)	)	-RRB-
cord-347298-7kqrl3rv	113	33	abilities	ability	NNS
cord-347298-7kqrl3rv	113	34	of	of	IN
cord-347298-7kqrl3rv	113	35	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	113	36	cells	cell	NNS
cord-347298-7kqrl3rv	113	37	,	,	,
cord-347298-7kqrl3rv	113	38	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	113	39	,	,	,
cord-347298-7kqrl3rv	113	40	and	and	CC
cord-347298-7kqrl3rv	113	41	some	some	DT
cord-347298-7kqrl3rv	113	42	B	b	NN
cord-347298-7kqrl3rv	113	43	cells	cell	NNS
cord-347298-7kqrl3rv	113	44	(	(	-LRB-
cord-347298-7kqrl3rv	113	45	Kelsall	Kelsall	NNP
cord-347298-7kqrl3rv	113	46	and	and	CC
cord-347298-7kqrl3rv	113	47	Rescigno	Rescigno	NNP
cord-347298-7kqrl3rv	113	48	2004	2004	CD
cord-347298-7kqrl3rv	113	49	;	;	:
cord-347298-7kqrl3rv	113	50	Spörri	Spörri	NNP
cord-347298-7kqrl3rv	113	51	and	and	CC
cord-347298-7kqrl3rv	113	52	Reis	Reis	NNP
cord-347298-7kqrl3rv	113	53	e	e	NN
cord-347298-7kqrl3rv	113	54	Sousa	Sousa	NNP
cord-347298-7kqrl3rv	113	55	2005	2005	CD
cord-347298-7kqrl3rv	113	56	)	)	-RRB-
cord-347298-7kqrl3rv	113	57	.	.	.
cord-347298-7kqrl3rv	114	1	Among	among	IN
cord-347298-7kqrl3rv	114	2	the	the	DT
cord-347298-7kqrl3rv	114	3	cell	cell	NN
cord-347298-7kqrl3rv	114	4	types	type	NNS
cord-347298-7kqrl3rv	114	5	that	that	WDT
cord-347298-7kqrl3rv	114	6	mediate	mediate	VBP
cord-347298-7kqrl3rv	114	7	the	the	DT
cord-347298-7kqrl3rv	114	8	innate	innate	JJ
cord-347298-7kqrl3rv	114	9	immune	immune	JJ
cord-347298-7kqrl3rv	114	10	response	response	NN
cord-347298-7kqrl3rv	114	11	,	,	,
cord-347298-7kqrl3rv	114	12	NK	NK	NNP
cord-347298-7kqrl3rv	114	13	cells	cell	NNS
cord-347298-7kqrl3rv	114	14	represent	represent	VBP
cord-347298-7kqrl3rv	114	15	a	a	DT
cord-347298-7kqrl3rv	114	16	special	special	JJ
cord-347298-7kqrl3rv	114	17	case	case	NN
cord-347298-7kqrl3rv	114	18	.	.	.
cord-347298-7kqrl3rv	115	1	These	these	DT
cord-347298-7kqrl3rv	115	2	cells	cell	NNS
cord-347298-7kqrl3rv	115	3	are	be	VBP
cord-347298-7kqrl3rv	115	4	of	of	IN
cord-347298-7kqrl3rv	115	5	the	the	DT
cord-347298-7kqrl3rv	115	6	lymphocytic	lymphocytic	JJ
cord-347298-7kqrl3rv	115	7	lineage	lineage	NN
cord-347298-7kqrl3rv	115	8	,	,	,
cord-347298-7kqrl3rv	115	9	but	but	CC
cord-347298-7kqrl3rv	115	10	they	-PRON-	PRP
cord-347298-7kqrl3rv	115	11	are	be	VBP
cord-347298-7kqrl3rv	115	12	capable	capable	JJ
cord-347298-7kqrl3rv	115	13	of	of	IN
cord-347298-7kqrl3rv	115	14	spontaneously	spontaneously	RB
cord-347298-7kqrl3rv	115	15	attacking	attack	VBG
cord-347298-7kqrl3rv	115	16	target	target	NN
cord-347298-7kqrl3rv	115	17	cells	cell	NNS
cord-347298-7kqrl3rv	115	18	without	without	IN
cord-347298-7kqrl3rv	115	19	prior	prior	JJ
cord-347298-7kqrl3rv	115	20	sensitization	sensitization	NN
cord-347298-7kqrl3rv	115	21	by	by	IN
cord-347298-7kqrl3rv	115	22	exposure	exposure	NN
cord-347298-7kqrl3rv	115	23	to	to	IN
cord-347298-7kqrl3rv	115	24	antigen	antigen	NN
cord-347298-7kqrl3rv	115	25	(	(	-LRB-
cord-347298-7kqrl3rv	115	26	Mori	Mori	NNP
cord-347298-7kqrl3rv	115	27	et	et	FW
cord-347298-7kqrl3rv	115	28	al	al	NNP
cord-347298-7kqrl3rv	115	29	.	.	NNP
cord-347298-7kqrl3rv	115	30	2001	2001	CD
cord-347298-7kqrl3rv	115	31	;	;	:
cord-347298-7kqrl3rv	115	32	Westermann	Westermann	NNP
cord-347298-7kqrl3rv	115	33	and	and	CC
cord-347298-7kqrl3rv	115	34	Pabst	Pabst	NNP
cord-347298-7kqrl3rv	115	35	1992	1992	CD
cord-347298-7kqrl3rv	115	36	)	)	-RRB-
cord-347298-7kqrl3rv	115	37	.	.	.
cord-347298-7kqrl3rv	116	1	Through	through	IN
cord-347298-7kqrl3rv	116	2	a	a	DT
cord-347298-7kqrl3rv	116	3	complex	complex	NN
cord-347298-7kqrl3rv	116	4	of	of	IN
cord-347298-7kqrl3rv	116	5	specific	specific	JJ
cord-347298-7kqrl3rv	116	6	receptors	receptor	NNS
cord-347298-7kqrl3rv	116	7	on	on	IN
cord-347298-7kqrl3rv	116	8	their	-PRON-	PRP$
cord-347298-7kqrl3rv	116	9	surface	surface	NN
cord-347298-7kqrl3rv	116	10	,	,	,
cord-347298-7kqrl3rv	116	11	NK	NK	NNP
cord-347298-7kqrl3rv	116	12	cells	cell	NNS
cord-347298-7kqrl3rv	116	13	are	be	VBP
cord-347298-7kqrl3rv	116	14	able	able	JJ
cord-347298-7kqrl3rv	116	15	to	to	TO
cord-347298-7kqrl3rv	116	16	recognize	recognize	VB
cord-347298-7kqrl3rv	116	17	and	and	CC
cord-347298-7kqrl3rv	116	18	directly	directly	RB
cord-347298-7kqrl3rv	116	19	target	target	VB
cord-347298-7kqrl3rv	116	20	transformed	transform	VBN
cord-347298-7kqrl3rv	116	21	cells	cell	NNS
cord-347298-7kqrl3rv	116	22	,	,	,
cord-347298-7kqrl3rv	116	23	such	such	JJ
cord-347298-7kqrl3rv	116	24	as	as	IN
cord-347298-7kqrl3rv	116	25	virally	virally	RB
cord-347298-7kqrl3rv	116	26	infected	infect	VBN
cord-347298-7kqrl3rv	116	27	or	or	CC
cord-347298-7kqrl3rv	116	28	tumor	tumor	NN
cord-347298-7kqrl3rv	116	29	cells	cell	NNS
cord-347298-7kqrl3rv	116	30	(	(	-LRB-
cord-347298-7kqrl3rv	116	31	Lanier	Lanier	NNP
cord-347298-7kqrl3rv	116	32	2001	2001	CD
cord-347298-7kqrl3rv	116	33	;	;	:
cord-347298-7kqrl3rv	117	1	Mori	Mori	NNP
cord-347298-7kqrl3rv	117	2	et	et	FW
cord-347298-7kqrl3rv	117	3	al	al	NNP
cord-347298-7kqrl3rv	117	4	.	.	NNP
cord-347298-7kqrl3rv	117	5	2001	2001	CD
cord-347298-7kqrl3rv	117	6	)	)	-RRB-
cord-347298-7kqrl3rv	117	7	.	.	.
cord-347298-7kqrl3rv	118	1	In	in	IN
cord-347298-7kqrl3rv	118	2	this	this	DT
cord-347298-7kqrl3rv	118	3	,	,	,
cord-347298-7kqrl3rv	118	4	NK	NK	NNP
cord-347298-7kqrl3rv	118	5	cells	cell	NNS
cord-347298-7kqrl3rv	118	6	provide	provide	VBP
cord-347298-7kqrl3rv	118	7	a	a	DT
cord-347298-7kqrl3rv	118	8	first	first	JJ
cord-347298-7kqrl3rv	118	9	-	-	HYPH
cord-347298-7kqrl3rv	118	10	line	line	NN
cord-347298-7kqrl3rv	118	11	of	of	IN
cord-347298-7kqrl3rv	118	12	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	118	13	defense	defense	NN
cord-347298-7kqrl3rv	118	14	within	within	IN
cord-347298-7kqrl3rv	118	15	the	the	DT
cord-347298-7kqrl3rv	118	16	context	context	NN
cord-347298-7kqrl3rv	118	17	of	of	IN
cord-347298-7kqrl3rv	118	18	the	the	DT
cord-347298-7kqrl3rv	118	19	innate	innate	JJ
cord-347298-7kqrl3rv	118	20	immune	immune	JJ
cord-347298-7kqrl3rv	118	21	response	response	NN
cord-347298-7kqrl3rv	118	22	,	,	,
cord-347298-7kqrl3rv	118	23	but	but	CC
cord-347298-7kqrl3rv	118	24	activated	activate	VBN
cord-347298-7kqrl3rv	118	25	NK	NK	NNP
cord-347298-7kqrl3rv	118	26	cells	cell	NNS
cord-347298-7kqrl3rv	118	27	also	also	RB
cord-347298-7kqrl3rv	118	28	participate	participate	VBP
cord-347298-7kqrl3rv	118	29	in	in	IN
cord-347298-7kqrl3rv	118	30	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	118	31	immunity	immunity	NN
cord-347298-7kqrl3rv	118	32	,	,	,
cord-347298-7kqrl3rv	118	33	both	both	DT
cord-347298-7kqrl3rv	118	34	as	as	IN
cord-347298-7kqrl3rv	118	35	regulators	regulator	NNS
cord-347298-7kqrl3rv	118	36	and	and	CC
cord-347298-7kqrl3rv	118	37	as	as	IN
cord-347298-7kqrl3rv	118	38	effector	effector	NN
cord-347298-7kqrl3rv	118	39	cells	cell	NNS
cord-347298-7kqrl3rv	118	40	of	of	IN
cord-347298-7kqrl3rv	118	41	the	the	DT
cord-347298-7kqrl3rv	118	42	response	response	NN
cord-347298-7kqrl3rv	118	43	(	(	-LRB-
cord-347298-7kqrl3rv	118	44	Mocikat	Mocikat	NNP
cord-347298-7kqrl3rv	118	45	et	et	FW
cord-347298-7kqrl3rv	118	46	al	al	NNP
cord-347298-7kqrl3rv	118	47	.	.	.
cord-347298-7kqrl3rv	119	1	2003	2003	CD
cord-347298-7kqrl3rv	119	2	;	;	:
cord-347298-7kqrl3rv	119	3	Raulet	Raulet	NNP
cord-347298-7kqrl3rv	119	4	2004	2004	CD
cord-347298-7kqrl3rv	119	5	)	)	-RRB-
cord-347298-7kqrl3rv	119	6	.	.	.
cord-347298-7kqrl3rv	120	1	Highly	highly	RB
cord-347298-7kqrl3rv	120	2	specific	specific	JJ
cord-347298-7kqrl3rv	120	3	interactions	interaction	NNS
cord-347298-7kqrl3rv	120	4	between	between	IN
cord-347298-7kqrl3rv	120	5	APCs	apc	NNS
cord-347298-7kqrl3rv	120	6	and	and	CC
cord-347298-7kqrl3rv	120	7	T	t	NN
cord-347298-7kqrl3rv	120	8	cells	cell	NNS
cord-347298-7kqrl3rv	120	9	,	,	,
cord-347298-7kqrl3rv	120	10	mediated	mediate	VBN
cord-347298-7kqrl3rv	120	11	via	via	IN
cord-347298-7kqrl3rv	120	12	the	the	DT
cord-347298-7kqrl3rv	120	13	polymorphic	polymorphic	JJ
cord-347298-7kqrl3rv	120	14	proteins	protein	NNS
cord-347298-7kqrl3rv	120	15	of	of	IN
cord-347298-7kqrl3rv	120	16	the	the	DT
cord-347298-7kqrl3rv	120	17	major	major	JJ
cord-347298-7kqrl3rv	120	18	histocompatibility	histocompatibility	NN
cord-347298-7kqrl3rv	120	19	complex	complex	NN
cord-347298-7kqrl3rv	120	20	(	(	-LRB-
cord-347298-7kqrl3rv	120	21	MHC	MHC	NNP
cord-347298-7kqrl3rv	120	22	;	;	:
cord-347298-7kqrl3rv	120	23	the	the	DT
cord-347298-7kqrl3rv	120	24	human	human	JJ
cord-347298-7kqrl3rv	120	25	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	120	26	antigen	antigen	NN
cord-347298-7kqrl3rv	120	27	(	(	-LRB-
cord-347298-7kqrl3rv	120	28	HLA	HLA	NNP
cord-347298-7kqrl3rv	120	29	)	)	-RRB-
cord-347298-7kqrl3rv	120	30	complex	complex	NN
cord-347298-7kqrl3rv	120	31	in	in	IN
cord-347298-7kqrl3rv	120	32	humans	human	NNS
cord-347298-7kqrl3rv	120	33	)	)	-RRB-
cord-347298-7kqrl3rv	120	34	and	and	CC
cord-347298-7kqrl3rv	120	35	antigen	antigen	NN
cord-347298-7kqrl3rv	120	36	-	-	HYPH
cord-347298-7kqrl3rv	120	37	specific	specific	JJ
cord-347298-7kqrl3rv	120	38	T	T	NNP
cord-347298-7kqrl3rv	120	39	cell	cell	NN
cord-347298-7kqrl3rv	120	40	receptors	receptor	NNS
cord-347298-7kqrl3rv	120	41	(	(	-LRB-
cord-347298-7kqrl3rv	120	42	TCRs	TCRs	NNP
cord-347298-7kqrl3rv	120	43	)	)	-RRB-
cord-347298-7kqrl3rv	120	44	,	,	,
cord-347298-7kqrl3rv	120	45	are	be	VBP
cord-347298-7kqrl3rv	120	46	crucial	crucial	JJ
cord-347298-7kqrl3rv	120	47	to	to	IN
cord-347298-7kqrl3rv	120	48	the	the	DT
cord-347298-7kqrl3rv	120	49	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	120	50	immune	immune	JJ
cord-347298-7kqrl3rv	120	51	response	response	NN
cord-347298-7kqrl3rv	120	52	.	.	.
cord-347298-7kqrl3rv	121	1	The	the	DT
cord-347298-7kqrl3rv	121	2	APCs	apc	NNS
cord-347298-7kqrl3rv	121	3	process	process	VBP
cord-347298-7kqrl3rv	121	4	exogenous	exogenous	JJ
cord-347298-7kqrl3rv	121	5	foreign	foreign	JJ
cord-347298-7kqrl3rv	121	6	proteins	protein	NNS
cord-347298-7kqrl3rv	121	7	into	into	IN
cord-347298-7kqrl3rv	121	8	short	short	JJ
cord-347298-7kqrl3rv	121	9	antigenic	antigenic	JJ
cord-347298-7kqrl3rv	121	10	peptides	peptide	NNS
cord-347298-7kqrl3rv	121	11	,	,	,
cord-347298-7kqrl3rv	121	12	which	which	WDT
cord-347298-7kqrl3rv	121	13	are	be	VBP
cord-347298-7kqrl3rv	121	14	then	then	RB
cord-347298-7kqrl3rv	121	15	incorporated	incorporate	VBN
cord-347298-7kqrl3rv	121	16	into	into	IN
cord-347298-7kqrl3rv	121	17	a	a	DT
cord-347298-7kqrl3rv	121	18	structural	structural	JJ
cord-347298-7kqrl3rv	121	19	groove	groove	NN
cord-347298-7kqrl3rv	121	20	on	on	IN
cord-347298-7kqrl3rv	121	21	the	the	DT
cord-347298-7kqrl3rv	121	22	external	external	JJ
cord-347298-7kqrl3rv	121	23	surface	surface	NN
cord-347298-7kqrl3rv	121	24	of	of	IN
cord-347298-7kqrl3rv	121	25	the	the	DT
cord-347298-7kqrl3rv	121	26	MHC	MHC	NNP
cord-347298-7kqrl3rv	121	27	protein	protein	NN
cord-347298-7kqrl3rv	121	28	complex	complex	NN
cord-347298-7kqrl3rv	121	29	during	during	IN
cord-347298-7kqrl3rv	121	30	its	-PRON-	PRP$
cord-347298-7kqrl3rv	121	31	assembly	assembly	NN
cord-347298-7kqrl3rv	121	32	within	within	IN
cord-347298-7kqrl3rv	121	33	the	the	DT
cord-347298-7kqrl3rv	121	34	cell	cell	NN
cord-347298-7kqrl3rv	121	35	(	(	-LRB-
cord-347298-7kqrl3rv	121	36	Cresswell	Cresswell	NNP
cord-347298-7kqrl3rv	121	37	et	et	NNP
cord-347298-7kqrl3rv	121	38	al	al	NNP
cord-347298-7kqrl3rv	121	39	.	.	.
cord-347298-7kqrl3rv	121	40	1999	1999	CD
cord-347298-7kqrl3rv	122	1	;	;	:
cord-347298-7kqrl3rv	122	2	Sant	Sant	NNP
cord-347298-7kqrl3rv	122	3	et	et	FW
cord-347298-7kqrl3rv	122	4	al	al	NNP
cord-347298-7kqrl3rv	122	5	.	.	.
cord-347298-7kqrl3rv	122	6	1999	1999	CD
cord-347298-7kqrl3rv	122	7	)	)	-RRB-
cord-347298-7kqrl3rv	122	8	.	.	.
cord-347298-7kqrl3rv	123	1	The	the	DT
cord-347298-7kqrl3rv	123	2	TCR	TCR	NNP
cord-347298-7kqrl3rv	123	3	on	on	IN
cord-347298-7kqrl3rv	123	4	the	the	DT
cord-347298-7kqrl3rv	123	5	surface	surface	NN
cord-347298-7kqrl3rv	123	6	of	of	IN
cord-347298-7kqrl3rv	123	7	a	a	DT
cord-347298-7kqrl3rv	123	8	T	t	NN
cord-347298-7kqrl3rv	123	9	cell	cell	NN
cord-347298-7kqrl3rv	123	10	that	that	WDT
cord-347298-7kqrl3rv	123	11	has	have	VBZ
cord-347298-7kqrl3rv	123	12	specificity	specificity	NN
cord-347298-7kqrl3rv	123	13	for	for	IN
cord-347298-7kqrl3rv	123	14	the	the	DT
cord-347298-7kqrl3rv	123	15	antigen	antigen	NN
cord-347298-7kqrl3rv	123	16	binds	bind	VBZ
cord-347298-7kqrl3rv	123	17	to	to	IN
cord-347298-7kqrl3rv	123	18	the	the	DT
cord-347298-7kqrl3rv	123	19	antigen	antigen	NN
cord-347298-7kqrl3rv	123	20	-	-	HYPH
cord-347298-7kqrl3rv	123	21	MHC	MHC	NNP
cord-347298-7kqrl3rv	123	22	complex	complex	NN
cord-347298-7kqrl3rv	123	23	on	on	IN
cord-347298-7kqrl3rv	123	24	the	the	DT
cord-347298-7kqrl3rv	123	25	APC	APC	NNP
cord-347298-7kqrl3rv	123	26	surface	surface	NN
cord-347298-7kqrl3rv	123	27	,	,	,
cord-347298-7kqrl3rv	123	28	which	which	WDT
cord-347298-7kqrl3rv	123	29	results	result	VBZ
cord-347298-7kqrl3rv	123	30	in	in	IN
cord-347298-7kqrl3rv	123	31	activation	activation	NN
cord-347298-7kqrl3rv	123	32	and	and	CC
cord-347298-7kqrl3rv	123	33	proliferation	proliferation	NN
cord-347298-7kqrl3rv	123	34	of	of	IN
cord-347298-7kqrl3rv	123	35	the	the	DT
cord-347298-7kqrl3rv	123	36	T	T	NNP
cord-347298-7kqrl3rv	123	37	cell	cell	NN
cord-347298-7kqrl3rv	123	38	.	.	.
cord-347298-7kqrl3rv	124	1	Circulating	circulate	VBG
cord-347298-7kqrl3rv	124	2	T	T	NNP
cord-347298-7kqrl3rv	124	3	cells	cell	NNS
cord-347298-7kqrl3rv	124	4	express	express	VBP
cord-347298-7kqrl3rv	124	5	one	one	CD
cord-347298-7kqrl3rv	124	6	of	of	IN
cord-347298-7kqrl3rv	124	7	two	two	CD
cord-347298-7kqrl3rv	124	8	coreceptors	coreceptor	NNS
cord-347298-7kqrl3rv	124	9	,	,	,
cord-347298-7kqrl3rv	124	10	CD4	CD4	NNP
cord-347298-7kqrl3rv	124	11	and	and	CC
cord-347298-7kqrl3rv	124	12	CD8	CD8	NNP
cord-347298-7kqrl3rv	124	13	,	,	,
cord-347298-7kqrl3rv	124	14	as	as	IN
cord-347298-7kqrl3rv	124	15	part	part	NN
cord-347298-7kqrl3rv	124	16	of	of	IN
cord-347298-7kqrl3rv	124	17	the	the	DT
cord-347298-7kqrl3rv	124	18	TCR	TCR	NNP
cord-347298-7kqrl3rv	124	19	,	,	,
cord-347298-7kqrl3rv	124	20	which	which	WDT
cord-347298-7kqrl3rv	124	21	direct	direct	VBP
cord-347298-7kqrl3rv	124	22	them	-PRON-	PRP
cord-347298-7kqrl3rv	124	23	to	to	TO
cord-347298-7kqrl3rv	124	24	recognize	recognize	VB
cord-347298-7kqrl3rv	124	25	antigens	antigen	NNS
cord-347298-7kqrl3rv	124	26	associated	associate	VBN
cord-347298-7kqrl3rv	124	27	with	with	IN
cord-347298-7kqrl3rv	124	28	either	either	CC
cord-347298-7kqrl3rv	124	29	MHC	MHC	NNP
cord-347298-7kqrl3rv	124	30	class	class	NN
cord-347298-7kqrl3rv	124	31	II	II	NNP
cord-347298-7kqrl3rv	124	32	or	or	CC
cord-347298-7kqrl3rv	124	33	I	-PRON-	PRP
cord-347298-7kqrl3rv	124	34	proteins	protein	NNS
cord-347298-7kqrl3rv	124	35	,	,	,
cord-347298-7kqrl3rv	124	36	respectively	respectively	RB
cord-347298-7kqrl3rv	124	37	(	(	-LRB-
cord-347298-7kqrl3rv	124	38	Janeway	Janeway	NNP
cord-347298-7kqrl3rv	124	39	1992	1992	CD
cord-347298-7kqrl3rv	124	40	)	)	-RRB-
cord-347298-7kqrl3rv	124	41	.	.	.
cord-347298-7kqrl3rv	125	1	Antigens	antigen	NNS
cord-347298-7kqrl3rv	125	2	are	be	VBP
cord-347298-7kqrl3rv	125	3	presented	present	VBN
cord-347298-7kqrl3rv	125	4	to	to	IN
cord-347298-7kqrl3rv	125	5	CD4	CD4	NNP
cord-347298-7kqrl3rv	125	6	þ	þ	NNP
cord-347298-7kqrl3rv	125	7	T	t	NN
cord-347298-7kqrl3rv	125	8	cells	cell	NNS
cord-347298-7kqrl3rv	125	9	by	by	IN
cord-347298-7kqrl3rv	125	10	the	the	DT
cord-347298-7kqrl3rv	125	11	so	so	RB
cord-347298-7kqrl3rv	125	12	-	-	HYPH
cord-347298-7kqrl3rv	125	13	called	call	VBN
cord-347298-7kqrl3rv	125	14	professional	professional	JJ
cord-347298-7kqrl3rv	125	15	APCs	apc	NNS
cord-347298-7kqrl3rv	125	16	that	that	WDT
cord-347298-7kqrl3rv	125	17	express	express	VBP
cord-347298-7kqrl3rv	125	18	MHC	MHC	NNP
cord-347298-7kqrl3rv	125	19	class	class	NN
cord-347298-7kqrl3rv	125	20	II	II	NNP
cord-347298-7kqrl3rv	125	21	antigens	antigen	NNS
cord-347298-7kqrl3rv	125	22	(	(	-LRB-
cord-347298-7kqrl3rv	125	23	i.e.	i.e.	FW
cord-347298-7kqrl3rv	125	24	,	,	,
cord-347298-7kqrl3rv	125	25	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	125	26	cells	cell	NNS
cord-347298-7kqrl3rv	125	27	,	,	,
cord-347298-7kqrl3rv	125	28	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	125	29	,	,	,
cord-347298-7kqrl3rv	125	30	and	and	CC
cord-347298-7kqrl3rv	125	31	B	b	NN
cord-347298-7kqrl3rv	125	32	cells	cell	NNS
cord-347298-7kqrl3rv	125	33	)	)	-RRB-
cord-347298-7kqrl3rv	126	1	(	(	-LRB-
cord-347298-7kqrl3rv	126	2	Heath	Heath	NNP
cord-347298-7kqrl3rv	126	3	and	and	CC
cord-347298-7kqrl3rv	126	4	Carbone	Carbone	NNP
cord-347298-7kqrl3rv	126	5	2001	2001	CD
cord-347298-7kqrl3rv	126	6	;	;	:
cord-347298-7kqrl3rv	126	7	Unanue	Unanue	NNP
cord-347298-7kqrl3rv	126	8	1984	1984	CD
cord-347298-7kqrl3rv	126	9	)	)	-RRB-
cord-347298-7kqrl3rv	126	10	.	.	.
cord-347298-7kqrl3rv	127	1	The	the	DT
cord-347298-7kqrl3rv	127	2	CD8	CD8	NNP
cord-347298-7kqrl3rv	127	3	þ	þ	NNP
cord-347298-7kqrl3rv	127	4	T	t	NN
cord-347298-7kqrl3rv	127	5	cells	cell	NNS
cord-347298-7kqrl3rv	127	6	recognize	recognize	VBP
cord-347298-7kqrl3rv	127	7	antigens	antigen	NNS
cord-347298-7kqrl3rv	127	8	presented	present	VBN
cord-347298-7kqrl3rv	127	9	in	in	IN
cord-347298-7kqrl3rv	127	10	the	the	DT
cord-347298-7kqrl3rv	127	11	context	context	NN
cord-347298-7kqrl3rv	127	12	of	of	IN
cord-347298-7kqrl3rv	127	13	MHC	MHC	NNP
cord-347298-7kqrl3rv	127	14	class	class	NN
cord-347298-7kqrl3rv	127	15	I	-PRON-	PRP
cord-347298-7kqrl3rv	127	16	proteins	protein	NNS
cord-347298-7kqrl3rv	127	17	,	,	,
cord-347298-7kqrl3rv	127	18	which	which	WDT
cord-347298-7kqrl3rv	127	19	are	be	VBP
cord-347298-7kqrl3rv	127	20	expressed	express	VBN
cord-347298-7kqrl3rv	127	21	by	by	IN
cord-347298-7kqrl3rv	127	22	almost	almost	RB
cord-347298-7kqrl3rv	127	23	all	all	DT
cord-347298-7kqrl3rv	127	24	cell	cell	NN
cord-347298-7kqrl3rv	127	25	types	type	NNS
cord-347298-7kqrl3rv	127	26	in	in	IN
cord-347298-7kqrl3rv	127	27	the	the	DT
cord-347298-7kqrl3rv	127	28	body	body	NN
cord-347298-7kqrl3rv	127	29	.	.	.
cord-347298-7kqrl3rv	128	1	Activation	activation	NN
cord-347298-7kqrl3rv	128	2	of	of	IN
cord-347298-7kqrl3rv	128	3	the	the	DT
cord-347298-7kqrl3rv	128	4	T	T	NNP
cord-347298-7kqrl3rv	128	5	cell	cell	NN
cord-347298-7kqrl3rv	128	6	also	also	RB
cord-347298-7kqrl3rv	128	7	requires	require	VBZ
cord-347298-7kqrl3rv	128	8	physical	physical	JJ
cord-347298-7kqrl3rv	128	9	interaction	interaction	NN
cord-347298-7kqrl3rv	128	10	between	between	IN
cord-347298-7kqrl3rv	128	11	the	the	DT
cord-347298-7kqrl3rv	128	12	APC	APC	NNP
cord-347298-7kqrl3rv	128	13	and	and	CC
cord-347298-7kqrl3rv	128	14	T	T	NNP
cord-347298-7kqrl3rv	128	15	cell	cell	NN
cord-347298-7kqrl3rv	128	16	involving	involve	VBG
cord-347298-7kqrl3rv	128	17	costimulatory	costimulatory	NNP
cord-347298-7kqrl3rv	128	18	ligand	ligand	NN
cord-347298-7kqrl3rv	128	19	-	-	HYPH
cord-347298-7kqrl3rv	128	20	receptor	receptor	NN
cord-347298-7kqrl3rv	128	21	pairs	pair	NNS
cord-347298-7kqrl3rv	128	22	,	,	,
cord-347298-7kqrl3rv	128	23	particularly	particularly	RB
cord-347298-7kqrl3rv	128	24	CD28	CD28	NNP
cord-347298-7kqrl3rv	128	25	:	:	:
cord-347298-7kqrl3rv	128	26	B7	B7	NNP
cord-347298-7kqrl3rv	128	27	and	and	CC
cord-347298-7kqrl3rv	128	28	CD40	CD40	NNP
cord-347298-7kqrl3rv	128	29	:	:	:
cord-347298-7kqrl3rv	128	30	CD40L	cd40l	NN
cord-347298-7kqrl3rv	128	31	,	,	,
cord-347298-7kqrl3rv	128	32	as	as	RB
cord-347298-7kqrl3rv	128	33	well	well	RB
cord-347298-7kqrl3rv	128	34	as	as	IN
cord-347298-7kqrl3rv	128	35	the	the	DT
cord-347298-7kqrl3rv	128	36	production	production	NN
cord-347298-7kqrl3rv	128	37	of	of	IN
cord-347298-7kqrl3rv	128	38	either	either	DT
cord-347298-7kqrl3rv	128	39	type	type	NN
cord-347298-7kqrl3rv	128	40	1	1	CD
cord-347298-7kqrl3rv	128	41	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	128	42	(	(	-LRB-
cord-347298-7kqrl3rv	128	43	IFN	IFN	NNP
cord-347298-7kqrl3rv	128	44	,	,	,
cord-347298-7kqrl3rv	128	45	IL2	IL2	NNP
cord-347298-7kqrl3rv	128	46	,	,	,
cord-347298-7kqrl3rv	128	47	and	and	CC
cord-347298-7kqrl3rv	128	48	IL12	IL12	NNP
cord-347298-7kqrl3rv	128	49	)	)	-RRB-
cord-347298-7kqrl3rv	128	50	or	or	CC
cord-347298-7kqrl3rv	128	51	type	type	NN
cord-347298-7kqrl3rv	128	52	2	2	CD
cord-347298-7kqrl3rv	128	53	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	128	54	(	(	-LRB-
cord-347298-7kqrl3rv	128	55	IL4	IL4	NNP
cord-347298-7kqrl3rv	128	56	,	,	,
cord-347298-7kqrl3rv	128	57	IL5	IL5	NNP
cord-347298-7kqrl3rv	128	58	,	,	,
cord-347298-7kqrl3rv	128	59	IL10	IL10	NNP
cord-347298-7kqrl3rv	128	60	,	,	,
cord-347298-7kqrl3rv	128	61	and	and	CC
cord-347298-7kqrl3rv	128	62	IL13	IL13	NNP
cord-347298-7kqrl3rv	128	63	)	)	-RRB-
cord-347298-7kqrl3rv	128	64	(	(	-LRB-
cord-347298-7kqrl3rv	128	65	Constant	constant	JJ
cord-347298-7kqrl3rv	128	66	and	and	CC
cord-347298-7kqrl3rv	128	67	Bottomly	Bottomly	NNP
cord-347298-7kqrl3rv	128	68	1997	1997	CD
cord-347298-7kqrl3rv	128	69	;	;	:
cord-347298-7kqrl3rv	128	70	Heath	Heath	NNP
cord-347298-7kqrl3rv	128	71	and	and	CC
cord-347298-7kqrl3rv	128	72	Carbone	Carbone	NNP
cord-347298-7kqrl3rv	128	73	2001	2001	CD
cord-347298-7kqrl3rv	128	74	;	;	:
cord-347298-7kqrl3rv	128	75	Moser	Moser	NNP
cord-347298-7kqrl3rv	128	76	and	and	CC
cord-347298-7kqrl3rv	128	77	Murphy	Murphy	NNP
cord-347298-7kqrl3rv	128	78	2000	2000	CD
cord-347298-7kqrl3rv	128	79	)	)	-RRB-
cord-347298-7kqrl3rv	128	80	.	.	.
cord-347298-7kqrl3rv	129	1	As	as	IN
cord-347298-7kqrl3rv	129	2	a	a	DT
cord-347298-7kqrl3rv	129	3	consequence	consequence	NN
cord-347298-7kqrl3rv	129	4	,	,	,
cord-347298-7kqrl3rv	129	5	the	the	DT
cord-347298-7kqrl3rv	129	6	activated	activate	VBN
cord-347298-7kqrl3rv	129	7	T	T	NNP
cord-347298-7kqrl3rv	129	8	cell	cell	NN
cord-347298-7kqrl3rv	129	9	can	can	MD
cord-347298-7kqrl3rv	129	10	have	have	VB
cord-347298-7kqrl3rv	129	11	a	a	DT
cord-347298-7kqrl3rv	129	12	number	number	NN
cord-347298-7kqrl3rv	129	13	of	of	IN
cord-347298-7kqrl3rv	129	14	different	different	JJ
cord-347298-7kqrl3rv	129	15	fates	fate	NNS
cord-347298-7kqrl3rv	129	16	depending	depend	VBG
cord-347298-7kqrl3rv	129	17	on	on	IN
cord-347298-7kqrl3rv	129	18	the	the	DT
cord-347298-7kqrl3rv	129	19	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	129	20	molecules	molecule	NNS
cord-347298-7kqrl3rv	129	21	engaged	engage	VBN
cord-347298-7kqrl3rv	129	22	and	and	CC
cord-347298-7kqrl3rv	129	23	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	129	24	produced	produce	VBN
cord-347298-7kqrl3rv	129	25	:	:	:
cord-347298-7kqrl3rv	129	26	activated	activate	VBN
cord-347298-7kqrl3rv	129	27	CD4	CD4	NNP
cord-347298-7kqrl3rv	129	28	þ	þ	NNP
cord-347298-7kqrl3rv	129	29	T	t	NN
cord-347298-7kqrl3rv	129	30	cells	cell	NNS
cord-347298-7kqrl3rv	129	31	may	may	MD
cord-347298-7kqrl3rv	129	32	become	become	VB
cord-347298-7kqrl3rv	129	33	type	type	NN
cord-347298-7kqrl3rv	129	34	1	1	CD
cord-347298-7kqrl3rv	129	35	helper	helper	NN
cord-347298-7kqrl3rv	129	36	(	(	-LRB-
cord-347298-7kqrl3rv	129	37	Th1	Th1	NNP
cord-347298-7kqrl3rv	129	38	)	)	-RRB-
cord-347298-7kqrl3rv	129	39	cells	cell	NNS
cord-347298-7kqrl3rv	129	40	,	,	,
cord-347298-7kqrl3rv	129	41	which	which	WDT
cord-347298-7kqrl3rv	129	42	direct	direct	JJ
cord-347298-7kqrl3rv	129	43	development	development	NN
cord-347298-7kqrl3rv	129	44	of	of	IN
cord-347298-7kqrl3rv	129	45	the	the	DT
cord-347298-7kqrl3rv	129	46	cellular	cellular	JJ
cord-347298-7kqrl3rv	129	47	immune	immune	JJ
cord-347298-7kqrl3rv	129	48	response	response	NN
cord-347298-7kqrl3rv	129	49	involving	involve	VBG
cord-347298-7kqrl3rv	129	50	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	129	51	CD8	CD8	NNP
cord-347298-7kqrl3rv	129	52	þ	þ	NNP
cord-347298-7kqrl3rv	129	53	T	T	NNP
cord-347298-7kqrl3rv	129	54	cells	cell	NNS
cord-347298-7kqrl3rv	129	55	,	,	,
cord-347298-7kqrl3rv	129	56	or	or	CC
cord-347298-7kqrl3rv	129	57	they	-PRON-	PRP
cord-347298-7kqrl3rv	129	58	may	may	MD
cord-347298-7kqrl3rv	129	59	become	become	VB
cord-347298-7kqrl3rv	129	60	type	type	NN
cord-347298-7kqrl3rv	129	61	2	2	CD
cord-347298-7kqrl3rv	129	62	helper	helper	NN
cord-347298-7kqrl3rv	129	63	(	(	-LRB-
cord-347298-7kqrl3rv	129	64	Th2	Th2	NNP
cord-347298-7kqrl3rv	129	65	)	)	-RRB-
cord-347298-7kqrl3rv	129	66	cells	cell	NNS
cord-347298-7kqrl3rv	129	67	,	,	,
cord-347298-7kqrl3rv	129	68	which	which	WDT
cord-347298-7kqrl3rv	129	69	promote	promote	VBP
cord-347298-7kqrl3rv	129	70	the	the	DT
cord-347298-7kqrl3rv	129	71	development	development	NN
cord-347298-7kqrl3rv	129	72	of	of	IN
cord-347298-7kqrl3rv	129	73	B	b	NN
cord-347298-7kqrl3rv	129	74	cells	cell	NNS
cord-347298-7kqrl3rv	129	75	into	into	IN
cord-347298-7kqrl3rv	129	76	antibody	antibody	NN
cord-347298-7kqrl3rv	129	77	-	-	HYPH
cord-347298-7kqrl3rv	129	78	secreting	secrete	VBG
cord-347298-7kqrl3rv	129	79	plasma	plasma	NN
cord-347298-7kqrl3rv	129	80	cells	cell	NNS
cord-347298-7kqrl3rv	129	81	following	follow	VBG
cord-347298-7kqrl3rv	129	82	interaction	interaction	NN
cord-347298-7kqrl3rv	129	83	with	with	IN
cord-347298-7kqrl3rv	129	84	their	-PRON-	PRP$
cord-347298-7kqrl3rv	129	85	antigen	antigen	NN
cord-347298-7kqrl3rv	129	86	(	(	-LRB-
cord-347298-7kqrl3rv	129	87	DeFranco	DeFranco	NNP
cord-347298-7kqrl3rv	129	88	1987	1987	CD
cord-347298-7kqrl3rv	129	89	)	)	-RRB-
cord-347298-7kqrl3rv	129	90	.	.	.
cord-347298-7kqrl3rv	130	1	Recently	recently	RB
cord-347298-7kqrl3rv	130	2	,	,	,
cord-347298-7kqrl3rv	130	3	a	a	DT
cord-347298-7kqrl3rv	130	4	new	new	JJ
cord-347298-7kqrl3rv	130	5	Th	Th	NNP
cord-347298-7kqrl3rv	130	6	effector	effector	NN
cord-347298-7kqrl3rv	130	7	cell	cell	NN
cord-347298-7kqrl3rv	130	8	subset	subset	NN
cord-347298-7kqrl3rv	130	9	(	(	-LRB-
cord-347298-7kqrl3rv	130	10	Th17	Th17	NNP
cord-347298-7kqrl3rv	130	11	)	)	-RRB-
cord-347298-7kqrl3rv	131	1	developmentally	developmentally	RB
cord-347298-7kqrl3rv	131	2	related	related	JJ
cord-347298-7kqrl3rv	131	3	to	to	IN
cord-347298-7kqrl3rv	131	4	Th1	th1	NN
cord-347298-7kqrl3rv	131	5	cells	cell	NNS
cord-347298-7kqrl3rv	131	6	,	,	,
cord-347298-7kqrl3rv	131	7	but	but	CC
cord-347298-7kqrl3rv	131	8	producing	produce	VBG
cord-347298-7kqrl3rv	131	9	IL17	IL17	NNP
cord-347298-7kqrl3rv	131	10	,	,	,
cord-347298-7kqrl3rv	131	11	IL21	IL21	NNP
cord-347298-7kqrl3rv	131	12	,	,	,
cord-347298-7kqrl3rv	131	13	and	and	CC
cord-347298-7kqrl3rv	131	14	IL22	IL22	NNP
cord-347298-7kqrl3rv	131	15	has	have	VBZ
cord-347298-7kqrl3rv	131	16	been	be	VBN
cord-347298-7kqrl3rv	131	17	described	describe	VBN
cord-347298-7kqrl3rv	131	18	(	(	-LRB-
cord-347298-7kqrl3rv	131	19	Ouyang	Ouyang	NNP
cord-347298-7kqrl3rv	131	20	et	et	NNP
cord-347298-7kqrl3rv	131	21	al	al	NNP
cord-347298-7kqrl3rv	131	22	.	.	NNP
cord-347298-7kqrl3rv	131	23	2008	2008	CD
cord-347298-7kqrl3rv	131	24	;	;	:
cord-347298-7kqrl3rv	131	25	Romagnani	Romagnani	NNP
cord-347298-7kqrl3rv	131	26	2008	2008	CD
cord-347298-7kqrl3rv	131	27	)	)	-RRB-
cord-347298-7kqrl3rv	131	28	.	.	.
cord-347298-7kqrl3rv	132	1	These	these	DT
cord-347298-7kqrl3rv	132	2	Th17	Th17	NNP
cord-347298-7kqrl3rv	132	3	cells	cell	NNS
cord-347298-7kqrl3rv	132	4	direct	direct	VBP
cord-347298-7kqrl3rv	132	5	a	a	DT
cord-347298-7kqrl3rv	132	6	number	number	NN
cord-347298-7kqrl3rv	132	7	of	of	IN
cord-347298-7kqrl3rv	132	8	responses	response	NNS
cord-347298-7kqrl3rv	132	9	involved	involve	VBN
cord-347298-7kqrl3rv	132	10	in	in	IN
cord-347298-7kqrl3rv	132	11	protection	protection	NN
cord-347298-7kqrl3rv	132	12	against	against	IN
cord-347298-7kqrl3rv	132	13	extracellular	extracellular	JJ
cord-347298-7kqrl3rv	132	14	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	132	15	,	,	,
cord-347298-7kqrl3rv	132	16	including	include	VBG
cord-347298-7kqrl3rv	132	17	recruitment	recruitment	NN
cord-347298-7kqrl3rv	132	18	and	and	CC
cord-347298-7kqrl3rv	132	19	activation	activation	NN
cord-347298-7kqrl3rv	132	20	of	of	IN
cord-347298-7kqrl3rv	132	21	the	the	DT
cord-347298-7kqrl3rv	132	22	major	major	JJ
cord-347298-7kqrl3rv	132	23	circulating	circulate	VBG
cord-347298-7kqrl3rv	132	24	PMN	PMN	NNP
cord-347298-7kqrl3rv	132	25	subset	subset	VBN
cord-347298-7kqrl3rv	132	26	,	,	,
cord-347298-7kqrl3rv	132	27	the	the	DT
cord-347298-7kqrl3rv	132	28	neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	132	29	,	,	,
cord-347298-7kqrl3rv	132	30	differentiation	differentiation	NN
cord-347298-7kqrl3rv	132	31	of	of	IN
cord-347298-7kqrl3rv	132	32	B	b	NN
cord-347298-7kqrl3rv	132	33	cells	cell	NNS
cord-347298-7kqrl3rv	132	34	,	,	,
cord-347298-7kqrl3rv	132	35	and	and	CC
cord-347298-7kqrl3rv	132	36	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	132	37	reactions	reaction	NNS
cord-347298-7kqrl3rv	132	38	of	of	IN
cord-347298-7kqrl3rv	132	39	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	132	40	cells	cell	NNS
cord-347298-7kqrl3rv	132	41	.	.	.
cord-347298-7kqrl3rv	133	1	However	however	RB
cord-347298-7kqrl3rv	133	2	,	,	,
cord-347298-7kqrl3rv	133	3	this	this	DT
cord-347298-7kqrl3rv	133	4	cell	cell	NN
cord-347298-7kqrl3rv	133	5	subset	subset	NN
cord-347298-7kqrl3rv	133	6	has	have	VBZ
cord-347298-7kqrl3rv	133	7	also	also	RB
cord-347298-7kqrl3rv	133	8	been	be	VBN
cord-347298-7kqrl3rv	133	9	implicated	implicate	VBN
cord-347298-7kqrl3rv	133	10	in	in	IN
cord-347298-7kqrl3rv	133	11	the	the	DT
cord-347298-7kqrl3rv	133	12	development	development	NN
cord-347298-7kqrl3rv	133	13	of	of	IN
cord-347298-7kqrl3rv	133	14	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	133	15	diseases	disease	NNS
cord-347298-7kqrl3rv	133	16	and	and	CC
cord-347298-7kqrl3rv	133	17	,	,	,
cord-347298-7kqrl3rv	133	18	along	along	IN
cord-347298-7kqrl3rv	133	19	with	with	IN
cord-347298-7kqrl3rv	133	20	Th2	th2	CD
cord-347298-7kqrl3rv	133	21	cells	cell	NNS
cord-347298-7kqrl3rv	133	22	,	,	,
cord-347298-7kqrl3rv	133	23	in	in	IN
cord-347298-7kqrl3rv	133	24	allergy	allergy	NN
cord-347298-7kqrl3rv	133	25	(	(	-LRB-
cord-347298-7kqrl3rv	133	26	Oboki	Oboki	NNP
cord-347298-7kqrl3rv	133	27	et	et	NNP
cord-347298-7kqrl3rv	133	28	al	al	NNP
cord-347298-7kqrl3rv	133	29	.	.	NNP
cord-347298-7kqrl3rv	133	30	2008	2008	CD
cord-347298-7kqrl3rv	133	31	;	;	:
cord-347298-7kqrl3rv	133	32	Ouyang	Ouyang	NNP
cord-347298-7kqrl3rv	133	33	et	et	NNP
cord-347298-7kqrl3rv	133	34	al	al	NNP
cord-347298-7kqrl3rv	133	35	.	.	NNP
cord-347298-7kqrl3rv	133	36	2008	2008	CD
cord-347298-7kqrl3rv	133	37	)	)	-RRB-
cord-347298-7kqrl3rv	133	38	.	.	.
cord-347298-7kqrl3rv	134	1	The	the	DT
cord-347298-7kqrl3rv	134	2	absence	absence	NN
cord-347298-7kqrl3rv	134	3	of	of	IN
cord-347298-7kqrl3rv	134	4	appropriate	appropriate	JJ
cord-347298-7kqrl3rv	134	5	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	134	6	molecule	molecule	NN
cord-347298-7kqrl3rv	134	7	interactions	interaction	NNS
cord-347298-7kqrl3rv	134	8	and/or	and/or	CC
cord-347298-7kqrl3rv	134	9	the	the	DT
cord-347298-7kqrl3rv	134	10	presence	presence	NN
cord-347298-7kqrl3rv	134	11	of	of	IN
cord-347298-7kqrl3rv	134	12	specific	specific	JJ
cord-347298-7kqrl3rv	134	13	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	134	14	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	134	15	may	may	MD
cord-347298-7kqrl3rv	134	16	also	also	RB
cord-347298-7kqrl3rv	134	17	lead	lead	VB
cord-347298-7kqrl3rv	134	18	to	to	IN
cord-347298-7kqrl3rv	134	19	T	T	NNP
cord-347298-7kqrl3rv	134	20	cell	cell	NN
cord-347298-7kqrl3rv	134	21	inactivation	inactivation	NN
cord-347298-7kqrl3rv	134	22	and	and	CC
cord-347298-7kqrl3rv	134	23	deletion	deletion	NN
cord-347298-7kqrl3rv	134	24	or	or	CC
cord-347298-7kqrl3rv	134	25	generation	generation	NN
cord-347298-7kqrl3rv	134	26	of	of	IN
cord-347298-7kqrl3rv	134	27	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	134	28	(	(	-LRB-
cord-347298-7kqrl3rv	134	29	i.e.	i.e.	FW
cord-347298-7kqrl3rv	134	30	,	,	,
cord-347298-7kqrl3rv	134	31	suppressor	suppressor	NN
cord-347298-7kqrl3rv	134	32	)	)	-RRB-
cord-347298-7kqrl3rv	135	1	T	T	NNP
cord-347298-7kqrl3rv	135	2	cell	cell	NN
cord-347298-7kqrl3rv	135	3	subsets	subset	NNS
cord-347298-7kqrl3rv	136	1	(	(	-LRB-
cord-347298-7kqrl3rv	136	2	Gilliet	Gilliet	NNP
cord-347298-7kqrl3rv	136	3	and	and	CC
cord-347298-7kqrl3rv	136	4	Liu	Liu	NNP
cord-347298-7kqrl3rv	136	5	2002	2002	CD
cord-347298-7kqrl3rv	136	6	;	;	:
cord-347298-7kqrl3rv	136	7	Nossal	Nossal	NNP
cord-347298-7kqrl3rv	136	8	1994	1994	CD
cord-347298-7kqrl3rv	136	9	;	;	:
cord-347298-7kqrl3rv	136	10	Piccirillo	Piccirillo	NNP
cord-347298-7kqrl3rv	136	11	and	and	CC
cord-347298-7kqrl3rv	136	12	Thornton	Thornton	NNP
cord-347298-7kqrl3rv	136	13	2004	2004	CD
cord-347298-7kqrl3rv	136	14	;	;	:
cord-347298-7kqrl3rv	136	15	Thompson	Thompson	NNP
cord-347298-7kqrl3rv	136	16	and	and	CC
cord-347298-7kqrl3rv	136	17	Thomas	Thomas	NNP
cord-347298-7kqrl3rv	136	18	2002	2002	CD
cord-347298-7kqrl3rv	136	19	)	)	-RRB-
cord-347298-7kqrl3rv	136	20	.	.	.
cord-347298-7kqrl3rv	137	1	Finally	finally	RB
cord-347298-7kqrl3rv	137	2	,	,	,
cord-347298-7kqrl3rv	137	3	at	at	IN
cord-347298-7kqrl3rv	137	4	least	least	JJS
cord-347298-7kqrl3rv	137	5	some	some	DT
cord-347298-7kqrl3rv	137	6	activated	activate	VBN
cord-347298-7kqrl3rv	137	7	T	t	NN
cord-347298-7kqrl3rv	137	8	and	and	CC
cord-347298-7kqrl3rv	137	9	B	B	NNP
cord-347298-7kqrl3rv	137	10	cell	cell	NN
cord-347298-7kqrl3rv	137	11	clones	clone	NNS
cord-347298-7kqrl3rv	137	12	persist	persist	VBP
cord-347298-7kqrl3rv	137	13	as	as	IN
cord-347298-7kqrl3rv	137	14	memory	memory	NN
cord-347298-7kqrl3rv	137	15	cells	cell	NNS
cord-347298-7kqrl3rv	137	16	following	follow	VBG
cord-347298-7kqrl3rv	137	17	the	the	DT
cord-347298-7kqrl3rv	137	18	resolution	resolution	NN
cord-347298-7kqrl3rv	137	19	of	of	IN
cord-347298-7kqrl3rv	137	20	the	the	DT
cord-347298-7kqrl3rv	137	21	immune	immune	JJ
cord-347298-7kqrl3rv	137	22	response	response	NN
cord-347298-7kqrl3rv	137	23	(	(	-LRB-
cord-347298-7kqrl3rv	137	24	Dutton	Dutton	NNP
cord-347298-7kqrl3rv	137	25	et	et	NNP
cord-347298-7kqrl3rv	137	26	al	al	NNP
cord-347298-7kqrl3rv	137	27	.	.	NNP
cord-347298-7kqrl3rv	137	28	1998	1998	CD
cord-347298-7kqrl3rv	137	29	;	;	:
cord-347298-7kqrl3rv	137	30	Schittek	Schittek	NNP
cord-347298-7kqrl3rv	137	31	and	and	CC
cord-347298-7kqrl3rv	137	32	Rajewsky	Rajewsky	NNP
cord-347298-7kqrl3rv	137	33	1990	1990	CD
cord-347298-7kqrl3rv	137	34	)	)	-RRB-
cord-347298-7kqrl3rv	137	35	.	.	.
cord-347298-7kqrl3rv	138	1	The	the	DT
cord-347298-7kqrl3rv	138	2	initial	initial	JJ
cord-347298-7kqrl3rv	138	3	antigen	antigen	NN
cord-347298-7kqrl3rv	138	4	presentation	presentation	NN
cord-347298-7kqrl3rv	138	5	and	and	CC
cord-347298-7kqrl3rv	138	6	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	138	7	activation	activation	NN
cord-347298-7kqrl3rv	138	8	events	event	NNS
cord-347298-7kqrl3rv	138	9	generally	generally	RB
cord-347298-7kqrl3rv	138	10	occur	occur	VBP
cord-347298-7kqrl3rv	138	11	in	in	IN
cord-347298-7kqrl3rv	138	12	the	the	DT
cord-347298-7kqrl3rv	138	13	secondary	secondary	JJ
cord-347298-7kqrl3rv	138	14	immune	immune	JJ
cord-347298-7kqrl3rv	138	15	tissues	tissue	NNS
cord-347298-7kqrl3rv	138	16	,	,	,
cord-347298-7kqrl3rv	138	17	the	the	DT
cord-347298-7kqrl3rv	138	18	local	local	JJ
cord-347298-7kqrl3rv	138	19	lymph	lymph	NN
cord-347298-7kqrl3rv	138	20	nodes	node	NNS
cord-347298-7kqrl3rv	138	21	and	and	CC
cord-347298-7kqrl3rv	138	22	spleen	spleen	NNS
cord-347298-7kqrl3rv	138	23	.	.	.
cord-347298-7kqrl3rv	139	1	Consequently	consequently	RB
cord-347298-7kqrl3rv	139	2	,	,	,
cord-347298-7kqrl3rv	139	3	an	an	DT
cord-347298-7kqrl3rv	139	4	effective	effective	JJ
cord-347298-7kqrl3rv	139	5	lymphatic	lymphatic	JJ
cord-347298-7kqrl3rv	139	6	drainage	drainage	NN
cord-347298-7kqrl3rv	139	7	is	be	VBZ
cord-347298-7kqrl3rv	139	8	usually	usually	RB
cord-347298-7kqrl3rv	139	9	necessary	necessary	JJ
cord-347298-7kqrl3rv	139	10	for	for	IN
cord-347298-7kqrl3rv	139	11	immune	immune	JJ
cord-347298-7kqrl3rv	139	12	responses	response	NNS
cord-347298-7kqrl3rv	139	13	to	to	TO
cord-347298-7kqrl3rv	139	14	develop	develop	VB
cord-347298-7kqrl3rv	139	15	in	in	IN
cord-347298-7kqrl3rv	139	16	a	a	DT
cord-347298-7kqrl3rv	139	17	particular	particular	JJ
cord-347298-7kqrl3rv	139	18	tissue	tissue	NN
cord-347298-7kqrl3rv	139	19	.	.	.
cord-347298-7kqrl3rv	140	1	However	however	RB
cord-347298-7kqrl3rv	140	2	,	,	,
cord-347298-7kqrl3rv	140	3	since	since	IN
cord-347298-7kqrl3rv	140	4	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	140	5	recirculate	recirculate	VBP
cord-347298-7kqrl3rv	140	6	through	through	IN
cord-347298-7kqrl3rv	140	7	tissues	tissue	NNS
cord-347298-7kqrl3rv	140	8	,	,	,
cord-347298-7kqrl3rv	140	9	many	many	JJ
cord-347298-7kqrl3rv	140	10	of	of	IN
cord-347298-7kqrl3rv	140	11	the	the	DT
cord-347298-7kqrl3rv	140	12	important	important	JJ
cord-347298-7kqrl3rv	140	13	events	event	NNS
cord-347298-7kqrl3rv	140	14	,	,	,
cord-347298-7kqrl3rv	140	15	including	include	VBG
cord-347298-7kqrl3rv	140	16	antigen	antigen	NN
cord-347298-7kqrl3rv	140	17	exposure	exposure	NN
cord-347298-7kqrl3rv	140	18	and	and	CC
cord-347298-7kqrl3rv	140	19	processing	processing	NN
cord-347298-7kqrl3rv	140	20	,	,	,
cord-347298-7kqrl3rv	140	21	antigen	antigen	NN
cord-347298-7kqrl3rv	140	22	recognition	recognition	NN
cord-347298-7kqrl3rv	140	23	by	by	IN
cord-347298-7kqrl3rv	140	24	antigen	antigen	NN
cord-347298-7kqrl3rv	140	25	-	-	HYPH
cord-347298-7kqrl3rv	140	26	exposed	expose	VBN
cord-347298-7kqrl3rv	140	27	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	140	28	,	,	,
cord-347298-7kqrl3rv	140	29	and	and	CC
cord-347298-7kqrl3rv	140	30	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	140	31	maturation	maturation	NN
cord-347298-7kqrl3rv	140	32	and	and	CC
cord-347298-7kqrl3rv	140	33	proliferation	proliferation	NN
cord-347298-7kqrl3rv	140	34	,	,	,
cord-347298-7kqrl3rv	140	35	also	also	RB
cord-347298-7kqrl3rv	140	36	occur	occur	VBP
cord-347298-7kqrl3rv	140	37	at	at	IN
cord-347298-7kqrl3rv	140	38	the	the	DT
cord-347298-7kqrl3rv	140	39	reaction	reaction	NN
cord-347298-7kqrl3rv	140	40	site	site	NN
cord-347298-7kqrl3rv	140	41	itself	-PRON-	PRP
cord-347298-7kqrl3rv	141	1	(	(	-LRB-
cord-347298-7kqrl3rv	141	2	Ascher	Ascher	NNP
cord-347298-7kqrl3rv	141	3	et	et	NNP
cord-347298-7kqrl3rv	141	4	al	al	NNP
cord-347298-7kqrl3rv	141	5	.	.	.
cord-347298-7kqrl3rv	141	6	1983	1983	CD
cord-347298-7kqrl3rv	141	7	;	;	:
cord-347298-7kqrl3rv	141	8	Gruber	Gruber	NNP
cord-347298-7kqrl3rv	141	9	1992	1992	CD
cord-347298-7kqrl3rv	141	10	;	;	:
cord-347298-7kqrl3rv	142	1	Pedersen	Pedersen	NNP
cord-347298-7kqrl3rv	142	2	and	and	CC
cord-347298-7kqrl3rv	142	3	Morris	Morris	NNP
cord-347298-7kqrl3rv	142	4	1970	1970	CD
cord-347298-7kqrl3rv	142	5	)	)	-RRB-
cord-347298-7kqrl3rv	142	6	.	.	.
cord-347298-7kqrl3rv	143	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	143	2	,	,	,
cord-347298-7kqrl3rv	143	3	while	while	IN
cord-347298-7kqrl3rv	143	4	it	-PRON-	PRP
cord-347298-7kqrl3rv	143	5	is	be	VBZ
cord-347298-7kqrl3rv	143	6	generally	generally	RB
cord-347298-7kqrl3rv	143	7	accepted	accept	VBN
cord-347298-7kqrl3rv	143	8	that	that	IN
cord-347298-7kqrl3rv	143	9	the	the	DT
cord-347298-7kqrl3rv	143	10	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	143	11	immune	immune	JJ
cord-347298-7kqrl3rv	143	12	system	system	NN
cord-347298-7kqrl3rv	143	13	is	be	VBZ
cord-347298-7kqrl3rv	143	14	activated	activate	VBN
cord-347298-7kqrl3rv	143	15	by	by	IN
cord-347298-7kqrl3rv	143	16	the	the	DT
cord-347298-7kqrl3rv	143	17	presence	presence	NN
cord-347298-7kqrl3rv	143	18	of	of	IN
cord-347298-7kqrl3rv	143	19	foreign	foreign	JJ
cord-347298-7kqrl3rv	143	20	antigens	antigen	NNS
cord-347298-7kqrl3rv	143	21	,	,	,
cord-347298-7kqrl3rv	143	22	there	there	EX
cord-347298-7kqrl3rv	143	23	is	be	VBZ
cord-347298-7kqrl3rv	143	24	an	an	DT
cord-347298-7kqrl3rv	143	25	alternative	alternative	JJ
cord-347298-7kqrl3rv	143	26	activation	activation	NN
cord-347298-7kqrl3rv	143	27	model	model	NN
cord-347298-7kqrl3rv	143	28	that	that	WDT
cord-347298-7kqrl3rv	143	29	combines	combine	VBZ
cord-347298-7kqrl3rv	143	30	elements	element	NNS
cord-347298-7kqrl3rv	143	31	of	of	IN
cord-347298-7kqrl3rv	143	32	both	both	CC
cord-347298-7kqrl3rv	143	33	the	the	DT
cord-347298-7kqrl3rv	143	34	innate	innate	JJ
cord-347298-7kqrl3rv	143	35	and	and	CC
cord-347298-7kqrl3rv	143	36	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	143	37	immune	immune	JJ
cord-347298-7kqrl3rv	143	38	systems	system	NNS
cord-347298-7kqrl3rv	143	39	.	.	.
cord-347298-7kqrl3rv	144	1	This	this	DT
cord-347298-7kqrl3rv	144	2	is	be	VBZ
cord-347298-7kqrl3rv	144	3	encapsulated	encapsulate	VBN
cord-347298-7kqrl3rv	144	4	by	by	IN
cord-347298-7kqrl3rv	144	5	the	the	DT
cord-347298-7kqrl3rv	144	6	'	'	``
cord-347298-7kqrl3rv	144	7	danger	danger	NN
cord-347298-7kqrl3rv	144	8	hypothesis	hypothesis	NN
cord-347298-7kqrl3rv	144	9	,	,	,
cord-347298-7kqrl3rv	144	10	'	'	''
cord-347298-7kqrl3rv	144	11	which	which	WDT
cord-347298-7kqrl3rv	144	12	proposes	propose	VBZ
cord-347298-7kqrl3rv	144	13	that	that	IN
cord-347298-7kqrl3rv	144	14	APCs	apc	NNS
cord-347298-7kqrl3rv	144	15	respond	respond	VBP
cord-347298-7kqrl3rv	144	16	to	to	IN
cord-347298-7kqrl3rv	144	17	substances	substance	NNS
cord-347298-7kqrl3rv	144	18	that	that	WDT
cord-347298-7kqrl3rv	144	19	cause	cause	VBP
cord-347298-7kqrl3rv	144	20	or	or	CC
cord-347298-7kqrl3rv	144	21	signal	signal	NN
cord-347298-7kqrl3rv	144	22	damage	damage	NN
cord-347298-7kqrl3rv	144	23	,	,	,
cord-347298-7kqrl3rv	144	24	rather	rather	RB
cord-347298-7kqrl3rv	144	25	than	than	IN
cord-347298-7kqrl3rv	144	26	to	to	IN
cord-347298-7kqrl3rv	144	27	those	those	DT
cord-347298-7kqrl3rv	144	28	that	that	WDT
cord-347298-7kqrl3rv	144	29	are	be	VBP
cord-347298-7kqrl3rv	144	30	simply	simply	RB
cord-347298-7kqrl3rv	144	31	foreign	foreign	JJ
cord-347298-7kqrl3rv	144	32	(	(	-LRB-
cord-347298-7kqrl3rv	144	33	Matzinger	Matzinger	NNP
cord-347298-7kqrl3rv	144	34	1994	1994	CD
cord-347298-7kqrl3rv	144	35	)	)	-RRB-
cord-347298-7kqrl3rv	144	36	.	.	.
cord-347298-7kqrl3rv	145	1	These	these	DT
cord-347298-7kqrl3rv	145	2	danger	danger	NN
cord-347298-7kqrl3rv	145	3	signals	signal	NNS
cord-347298-7kqrl3rv	145	4	include	include	VBP
cord-347298-7kqrl3rv	145	5	CD40L	cd40l	NN
cord-347298-7kqrl3rv	145	6	,	,	,
cord-347298-7kqrl3rv	145	7	the	the	DT
cord-347298-7kqrl3rv	145	8	early	early	JJ
cord-347298-7kqrl3rv	145	9	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	145	10	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	145	11	IL1	IL1	NNP
cord-347298-7kqrl3rv	145	12	and	and	CC
cord-347298-7kqrl3rv	145	13	TNF	TNF	NNP
cord-347298-7kqrl3rv	145	14	,	,	,
cord-347298-7kqrl3rv	145	15	IFNs	IFNs	NNP
cord-347298-7kqrl3rv	145	16	,	,	,
cord-347298-7kqrl3rv	145	17	and	and	CC
cord-347298-7kqrl3rv	145	18	heat	heat	NN
cord-347298-7kqrl3rv	145	19	-	-	HYPH
cord-347298-7kqrl3rv	145	20	shock	shock	NN
cord-347298-7kqrl3rv	145	21	proteins	protein	NNS
cord-347298-7kqrl3rv	145	22	as	as	RB
cord-347298-7kqrl3rv	145	23	well	well	RB
cord-347298-7kqrl3rv	145	24	as	as	IN
cord-347298-7kqrl3rv	145	25	substances	substance	NNS
cord-347298-7kqrl3rv	145	26	that	that	WDT
cord-347298-7kqrl3rv	145	27	are	be	VBP
cord-347298-7kqrl3rv	145	28	normally	normally	RB
cord-347298-7kqrl3rv	145	29	found	find	VBN
cord-347298-7kqrl3rv	145	30	only	only	RB
cord-347298-7kqrl3rv	145	31	inside	inside	JJ
cord-347298-7kqrl3rv	145	32	cells	cell	NNS
cord-347298-7kqrl3rv	145	33	(	(	-LRB-
cord-347298-7kqrl3rv	145	34	e.g.	e.g.	RB
cord-347298-7kqrl3rv	145	35	,	,	,
cord-347298-7kqrl3rv	145	36	nucleotides	nucleotide	NNS
cord-347298-7kqrl3rv	145	37	,	,	,
cord-347298-7kqrl3rv	145	38	unmethylated	unmethylate	VBN
cord-347298-7kqrl3rv	145	39	CpG	CpG	NNP
cord-347298-7kqrl3rv	145	40	sequences	sequence	NNS
cord-347298-7kqrl3rv	145	41	in	in	IN
cord-347298-7kqrl3rv	145	42	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	145	43	double	double	RB
cord-347298-7kqrl3rv	145	44	-	-	HYPH
cord-347298-7kqrl3rv	145	45	stranded	strand	VBN
cord-347298-7kqrl3rv	145	46	DNA	dna	NN
cord-347298-7kqrl3rv	145	47	)	)	-RRB-
cord-347298-7kqrl3rv	145	48	and	and	CC
cord-347298-7kqrl3rv	145	49	hyaluron	hyaluron	NNP
cord-347298-7kqrl3rv	145	50	breakdown	breakdown	NN
cord-347298-7kqrl3rv	145	51	products	product	NNS
cord-347298-7kqrl3rv	145	52	(	(	-LRB-
cord-347298-7kqrl3rv	145	53	Gallucci	Gallucci	NNP
cord-347298-7kqrl3rv	145	54	and	and	CC
cord-347298-7kqrl3rv	145	55	Matzinger	Matzinger	NNP
cord-347298-7kqrl3rv	145	56	2001	2001	CD
cord-347298-7kqrl3rv	145	57	)	)	-RRB-
cord-347298-7kqrl3rv	145	58	.	.	.
cord-347298-7kqrl3rv	146	1	In	in	IN
cord-347298-7kqrl3rv	146	2	this	this	DT
cord-347298-7kqrl3rv	146	3	model	model	NN
cord-347298-7kqrl3rv	146	4	,	,	,
cord-347298-7kqrl3rv	146	5	activation	activation	NN
cord-347298-7kqrl3rv	146	6	of	of	IN
cord-347298-7kqrl3rv	146	7	the	the	DT
cord-347298-7kqrl3rv	146	8	immune	immune	JJ
cord-347298-7kqrl3rv	146	9	system	system	NN
cord-347298-7kqrl3rv	146	10	occurs	occur	VBZ
cord-347298-7kqrl3rv	146	11	as	as	IN
cord-347298-7kqrl3rv	146	12	a	a	DT
cord-347298-7kqrl3rv	146	13	response	response	NN
cord-347298-7kqrl3rv	146	14	to	to	IN
cord-347298-7kqrl3rv	146	15	evidence	evidence	NN
cord-347298-7kqrl3rv	146	16	of	of	IN
cord-347298-7kqrl3rv	146	17	an	an	DT
cord-347298-7kqrl3rv	146	18	extant	extant	JJ
cord-347298-7kqrl3rv	146	19	threat	threat	NN
cord-347298-7kqrl3rv	146	20	,	,	,
cord-347298-7kqrl3rv	146	21	rather	rather	RB
cord-347298-7kqrl3rv	146	22	than	than	IN
cord-347298-7kqrl3rv	146	23	toward	toward	IN
cord-347298-7kqrl3rv	146	24	a	a	DT
cord-347298-7kqrl3rv	146	25	specific	specific	JJ
cord-347298-7kqrl3rv	146	26	feature	feature	NN
cord-347298-7kqrl3rv	146	27	of	of	IN
cord-347298-7kqrl3rv	146	28	the	the	DT
cord-347298-7kqrl3rv	146	29	threat	threat	NN
cord-347298-7kqrl3rv	146	30	itself	-PRON-	PRP
cord-347298-7kqrl3rv	146	31	.	.	.
cord-347298-7kqrl3rv	147	1	This	this	DT
cord-347298-7kqrl3rv	147	2	mechanism	mechanism	NN
cord-347298-7kqrl3rv	147	3	may	may	MD
cord-347298-7kqrl3rv	147	4	contribute	contribute	VB
cord-347298-7kqrl3rv	147	5	to	to	IN
cord-347298-7kqrl3rv	147	6	the	the	DT
cord-347298-7kqrl3rv	147	7	onset	onset	NN
cord-347298-7kqrl3rv	147	8	of	of	IN
cord-347298-7kqrl3rv	147	9	certain	certain	JJ
cord-347298-7kqrl3rv	147	10	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	147	11	diseases	disease	NNS
cord-347298-7kqrl3rv	147	12	.	.	.
cord-347298-7kqrl3rv	148	1	While	while	IN
cord-347298-7kqrl3rv	148	2	an	an	DT
cord-347298-7kqrl3rv	148	3	effective	effective	JJ
cord-347298-7kqrl3rv	148	4	immune	immune	JJ
cord-347298-7kqrl3rv	148	5	response	response	NN
cord-347298-7kqrl3rv	148	6	is	be	VBZ
cord-347298-7kqrl3rv	148	7	essential	essential	JJ
cord-347298-7kqrl3rv	148	8	for	for	IN
cord-347298-7kqrl3rv	148	9	protection	protection	NN
cord-347298-7kqrl3rv	148	10	of	of	IN
cord-347298-7kqrl3rv	148	11	the	the	DT
cord-347298-7kqrl3rv	148	12	host	host	NN
cord-347298-7kqrl3rv	148	13	from	from	IN
cord-347298-7kqrl3rv	148	14	a	a	DT
cord-347298-7kqrl3rv	148	15	range	range	NN
cord-347298-7kqrl3rv	148	16	of	of	IN
cord-347298-7kqrl3rv	148	17	threats	threat	NNS
cord-347298-7kqrl3rv	148	18	,	,	,
cord-347298-7kqrl3rv	148	19	the	the	DT
cord-347298-7kqrl3rv	148	20	immune	immune	JJ
cord-347298-7kqrl3rv	148	21	system	system	NN
cord-347298-7kqrl3rv	148	22	also	also	RB
cord-347298-7kqrl3rv	148	23	has	have	VBZ
cord-347298-7kqrl3rv	148	24	its	-PRON-	PRP$
cord-347298-7kqrl3rv	148	25	dark	dark	JJ
cord-347298-7kqrl3rv	148	26	side	side	NN
cord-347298-7kqrl3rv	148	27	.	.	.
cord-347298-7kqrl3rv	149	1	The	the	DT
cord-347298-7kqrl3rv	149	2	capacity	capacity	NN
cord-347298-7kqrl3rv	149	3	of	of	IN
cord-347298-7kqrl3rv	149	4	the	the	DT
cord-347298-7kqrl3rv	149	5	immune	immune	JJ
cord-347298-7kqrl3rv	149	6	system	system	NN
cord-347298-7kqrl3rv	149	7	for	for	IN
cord-347298-7kqrl3rv	149	8	destructiveness	destructiveness	NN
cord-347298-7kqrl3rv	149	9	is	be	VBZ
cord-347298-7kqrl3rv	149	10	expressed	express	VBN
cord-347298-7kqrl3rv	149	11	in	in	IN
cord-347298-7kqrl3rv	149	12	chronic	chronic	JJ
cord-347298-7kqrl3rv	149	13	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	149	14	and	and	CC
cord-347298-7kqrl3rv	149	15	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	149	16	diseases	disease	NNS
cord-347298-7kqrl3rv	149	17	,	,	,
cord-347298-7kqrl3rv	149	18	including	include	VBG
cord-347298-7kqrl3rv	149	19	those	those	DT
cord-347298-7kqrl3rv	149	20	that	that	WDT
cord-347298-7kqrl3rv	149	21	affect	affect	VBP
cord-347298-7kqrl3rv	149	22	the	the	DT
cord-347298-7kqrl3rv	149	23	male	male	JJ
cord-347298-7kqrl3rv	149	24	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	149	25	tract	tract	NN
cord-347298-7kqrl3rv	149	26	(	(	-LRB-
cord-347298-7kqrl3rv	149	27	Roper	Roper	NNP
cord-347298-7kqrl3rv	149	28	et	et	NNP
cord-347298-7kqrl3rv	149	29	al	al	NNP
cord-347298-7kqrl3rv	149	30	.	.	NNP
cord-347298-7kqrl3rv	149	31	1998	1998	CD
cord-347298-7kqrl3rv	149	32	;	;	:
cord-347298-7kqrl3rv	149	33	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	149	34	and	and	CC
cord-347298-7kqrl3rv	149	35	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	149	36	2005	2005	CD
cord-347298-7kqrl3rv	149	37	;	;	:
cord-347298-7kqrl3rv	149	38	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	149	39	et	et	NNP
cord-347298-7kqrl3rv	149	40	al	al	NNP
cord-347298-7kqrl3rv	149	41	.	.	NNP
cord-347298-7kqrl3rv	149	42	2008	2008	CD
cord-347298-7kqrl3rv	149	43	;	;	:
cord-347298-7kqrl3rv	149	44	Suominen	Suominen	NNP
cord-347298-7kqrl3rv	149	45	1995	1995	CD
cord-347298-7kqrl3rv	149	46	)	)	-RRB-
cord-347298-7kqrl3rv	149	47	.	.	.
cord-347298-7kqrl3rv	150	1	These	these	DT
cord-347298-7kqrl3rv	150	2	examples	example	NNS
cord-347298-7kqrl3rv	150	3	of	of	IN
cord-347298-7kqrl3rv	150	4	an	an	DT
cord-347298-7kqrl3rv	150	5	immune	immune	JJ
cord-347298-7kqrl3rv	150	6	system	system	NN
cord-347298-7kqrl3rv	150	7	seemingly	seemingly	RB
cord-347298-7kqrl3rv	150	8	out	out	IN
cord-347298-7kqrl3rv	150	9	of	of	IN
cord-347298-7kqrl3rv	150	10	control	control	NN
cord-347298-7kqrl3rv	150	11	highlight	highlight	VB
cord-347298-7kqrl3rv	150	12	the	the	DT
cord-347298-7kqrl3rv	150	13	crucial	crucial	JJ
cord-347298-7kqrl3rv	150	14	importance	importance	NN
cord-347298-7kqrl3rv	150	15	of	of	IN
cord-347298-7kqrl3rv	150	16	effective	effective	JJ
cord-347298-7kqrl3rv	150	17	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	150	18	.	.	.
cord-347298-7kqrl3rv	151	1	At	at	IN
cord-347298-7kqrl3rv	151	2	the	the	DT
cord-347298-7kqrl3rv	151	3	center	center	NN
cord-347298-7kqrl3rv	151	4	of	of	IN
cord-347298-7kqrl3rv	151	5	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	151	6	is	be	VBZ
cord-347298-7kqrl3rv	151	7	the	the	DT
cord-347298-7kqrl3rv	151	8	concept	concept	NN
cord-347298-7kqrl3rv	151	9	of	of	IN
cord-347298-7kqrl3rv	151	10	tolerance	tolerance	NN
cord-347298-7kqrl3rv	151	11	,	,	,
cord-347298-7kqrl3rv	151	12	or	or	CC
cord-347298-7kqrl3rv	151	13	the	the	DT
cord-347298-7kqrl3rv	151	14	capacity	capacity	NN
cord-347298-7kqrl3rv	151	15	of	of	IN
cord-347298-7kqrl3rv	151	16	the	the	DT
cord-347298-7kqrl3rv	151	17	immune	immune	JJ
cord-347298-7kqrl3rv	151	18	system	system	NN
cord-347298-7kqrl3rv	151	19	to	to	TO
cord-347298-7kqrl3rv	151	20	ignore	ignore	VB
cord-347298-7kqrl3rv	151	21	certain	certain	JJ
cord-347298-7kqrl3rv	151	22	molecular	molecular	JJ
cord-347298-7kqrl3rv	151	23	patterns	pattern	NNS
cord-347298-7kqrl3rv	151	24	,	,	,
cord-347298-7kqrl3rv	151	25	and	and	CC
cord-347298-7kqrl3rv	151	26	the	the	DT
cord-347298-7kqrl3rv	151	27	systems	system	NNS
cord-347298-7kqrl3rv	151	28	that	that	WDT
cord-347298-7kqrl3rv	151	29	restrain	restrain	VBP
cord-347298-7kqrl3rv	151	30	the	the	DT
cord-347298-7kqrl3rv	151	31	immune	immune	JJ
cord-347298-7kqrl3rv	151	32	response	response	NN
cord-347298-7kqrl3rv	151	33	once	once	IN
cord-347298-7kqrl3rv	151	34	its	-PRON-	PRP$
cord-347298-7kqrl3rv	151	35	usefulness	usefulness	NN
cord-347298-7kqrl3rv	151	36	has	have	VBZ
cord-347298-7kqrl3rv	151	37	expired	expire	VBN
cord-347298-7kqrl3rv	151	38	.	.	.
cord-347298-7kqrl3rv	152	1	Tolerance	tolerance	NN
cord-347298-7kqrl3rv	152	2	is	be	VBZ
cord-347298-7kqrl3rv	152	3	the	the	DT
cord-347298-7kqrl3rv	152	4	ability	ability	NN
cord-347298-7kqrl3rv	152	5	of	of	IN
cord-347298-7kqrl3rv	152	6	the	the	DT
cord-347298-7kqrl3rv	152	7	immune	immune	JJ
cord-347298-7kqrl3rv	152	8	system	system	NN
cord-347298-7kqrl3rv	152	9	to	to	TO
cord-347298-7kqrl3rv	152	10	discriminate	discriminate	VB
cord-347298-7kqrl3rv	152	11	self	self	NN
cord-347298-7kqrl3rv	152	12	from	from	IN
cord-347298-7kqrl3rv	152	13	nonself	nonself	NNP
cord-347298-7kqrl3rv	152	14	.	.	.
cord-347298-7kqrl3rv	153	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	153	2	is	be	VBZ
cord-347298-7kqrl3rv	153	3	fundamentally	fundamentally	RB
cord-347298-7kqrl3rv	153	4	based	base	VBN
cord-347298-7kqrl3rv	153	5	on	on	IN
cord-347298-7kqrl3rv	153	6	the	the	DT
cord-347298-7kqrl3rv	153	7	removal	removal	NN
cord-347298-7kqrl3rv	153	8	,	,	,
cord-347298-7kqrl3rv	153	9	inactivation	inactivation	NN
cord-347298-7kqrl3rv	153	10	,	,	,
cord-347298-7kqrl3rv	153	11	or	or	CC
cord-347298-7kqrl3rv	153	12	suppression	suppression	NN
cord-347298-7kqrl3rv	153	13	of	of	IN
cord-347298-7kqrl3rv	153	14	self	self	NN
cord-347298-7kqrl3rv	153	15	-	-	HYPH
cord-347298-7kqrl3rv	153	16	reactive	reactive	JJ
cord-347298-7kqrl3rv	153	17	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	153	18	subsets	subset	NNS
cord-347298-7kqrl3rv	153	19	,	,	,
cord-347298-7kqrl3rv	153	20	so	so	IN
cord-347298-7kqrl3rv	153	21	that	that	IN
cord-347298-7kqrl3rv	153	22	the	the	DT
cord-347298-7kqrl3rv	153	23	immune	immune	JJ
cord-347298-7kqrl3rv	153	24	system	system	NN
cord-347298-7kqrl3rv	153	25	becomes	become	VBZ
cord-347298-7kqrl3rv	153	26	effectively	effectively	RB
cord-347298-7kqrl3rv	153	27	incapable	incapable	JJ
cord-347298-7kqrl3rv	153	28	of	of	IN
cord-347298-7kqrl3rv	153	29	recognizing	recognize	VBG
cord-347298-7kqrl3rv	153	30	and	and	CC
cord-347298-7kqrl3rv	153	31	reacting	react	VBG
cord-347298-7kqrl3rv	153	32	to	to	IN
cord-347298-7kqrl3rv	153	33	these	these	DT
cord-347298-7kqrl3rv	153	34	antigens	antigen	NNS
cord-347298-7kqrl3rv	153	35	.	.	.
cord-347298-7kqrl3rv	154	1	Induction	induction	NN
cord-347298-7kqrl3rv	154	2	of	of	IN
cord-347298-7kqrl3rv	154	3	tolerance	tolerance	NN
cord-347298-7kqrl3rv	154	4	comprises	comprise	VBZ
cord-347298-7kqrl3rv	154	5	both	both	CC
cord-347298-7kqrl3rv	154	6	central	central	JJ
cord-347298-7kqrl3rv	154	7	and	and	CC
cord-347298-7kqrl3rv	154	8	peripheral	peripheral	JJ
cord-347298-7kqrl3rv	154	9	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	154	10	.	.	.
cord-347298-7kqrl3rv	155	1	The	the	DT
cord-347298-7kqrl3rv	155	2	central	central	JJ
cord-347298-7kqrl3rv	155	3	mechanism	mechanism	NN
cord-347298-7kqrl3rv	155	4	involves	involve	VBZ
cord-347298-7kqrl3rv	155	5	clonal	clonal	JJ
cord-347298-7kqrl3rv	155	6	deletion	deletion	NN
cord-347298-7kqrl3rv	155	7	of	of	IN
cord-347298-7kqrl3rv	155	8	T	T	NNP
cord-347298-7kqrl3rv	155	9	and	and	CC
cord-347298-7kqrl3rv	155	10	B	b	NN
cord-347298-7kqrl3rv	155	11	cell	cell	NN
cord-347298-7kqrl3rv	155	12	subsets	subset	NNS
cord-347298-7kqrl3rv	155	13	that	that	WDT
cord-347298-7kqrl3rv	155	14	are	be	VBP
cord-347298-7kqrl3rv	155	15	potentially	potentially	RB
cord-347298-7kqrl3rv	155	16	autoreactive	autoreactive	JJ
cord-347298-7kqrl3rv	155	17	,	,	,
cord-347298-7kqrl3rv	155	18	a	a	DT
cord-347298-7kqrl3rv	155	19	process	process	NN
cord-347298-7kqrl3rv	155	20	that	that	WDT
cord-347298-7kqrl3rv	155	21	normally	normally	RB
cord-347298-7kqrl3rv	155	22	occurs	occur	VBZ
cord-347298-7kqrl3rv	155	23	during	during	IN
cord-347298-7kqrl3rv	155	24	gestation	gestation	NN
cord-347298-7kqrl3rv	155	25	as	as	IN
cord-347298-7kqrl3rv	155	26	part	part	NN
cord-347298-7kqrl3rv	155	27	of	of	IN
cord-347298-7kqrl3rv	155	28	the	the	DT
cord-347298-7kqrl3rv	155	29	early	early	JJ
cord-347298-7kqrl3rv	155	30	maturation	maturation	NN
cord-347298-7kqrl3rv	155	31	of	of	IN
cord-347298-7kqrl3rv	155	32	the	the	DT
cord-347298-7kqrl3rv	155	33	immune	immune	JJ
cord-347298-7kqrl3rv	155	34	system	system	NN
cord-347298-7kqrl3rv	155	35	(	(	-LRB-
cord-347298-7kqrl3rv	155	36	Kappler	Kappler	NNP
cord-347298-7kqrl3rv	155	37	et	et	NNP
cord-347298-7kqrl3rv	155	38	al	al	NNP
cord-347298-7kqrl3rv	155	39	.	.	NNP
cord-347298-7kqrl3rv	155	40	1987	1987	CD
cord-347298-7kqrl3rv	155	41	;	;	:
cord-347298-7kqrl3rv	155	42	Nossal	Nossal	NNP
cord-347298-7kqrl3rv	155	43	1994	1994	CD
cord-347298-7kqrl3rv	155	44	)	)	-RRB-
cord-347298-7kqrl3rv	155	45	.	.	.
cord-347298-7kqrl3rv	156	1	Many	many	JJ
cord-347298-7kqrl3rv	156	2	details	detail	NNS
cord-347298-7kqrl3rv	156	3	of	of	IN
cord-347298-7kqrl3rv	156	4	this	this	DT
cord-347298-7kqrl3rv	156	5	editing	editing	NN
cord-347298-7kqrl3rv	156	6	process	process	NN
cord-347298-7kqrl3rv	156	7	remain	remain	VBP
cord-347298-7kqrl3rv	156	8	incompletely	incompletely	RB
cord-347298-7kqrl3rv	156	9	understood	understand	VBN
cord-347298-7kqrl3rv	156	10	,	,	,
cord-347298-7kqrl3rv	156	11	although	although	IN
cord-347298-7kqrl3rv	156	12	the	the	DT
cord-347298-7kqrl3rv	156	13	process	process	NN
cord-347298-7kqrl3rv	156	14	involves	involve	VBZ
cord-347298-7kqrl3rv	156	15	broad	broad	JJ
cord-347298-7kqrl3rv	156	16	expression	expression	NN
cord-347298-7kqrl3rv	156	17	by	by	IN
cord-347298-7kqrl3rv	156	18	thymic	thymic	JJ
cord-347298-7kqrl3rv	156	19	medullary	medullary	JJ
cord-347298-7kqrl3rv	156	20	cells	cell	NNS
cord-347298-7kqrl3rv	156	21	of	of	IN
cord-347298-7kqrl3rv	156	22	self	self	NN
cord-347298-7kqrl3rv	156	23	-	-	HYPH
cord-347298-7kqrl3rv	156	24	antigens	antigen	NNS
cord-347298-7kqrl3rv	156	25	,	,	,
cord-347298-7kqrl3rv	156	26	including	include	VBG
cord-347298-7kqrl3rv	156	27	many	many	JJ
cord-347298-7kqrl3rv	156	28	endocrine	endocrine	JJ
cord-347298-7kqrl3rv	156	29	tissue	tissue	NN
cord-347298-7kqrl3rv	156	30	-	-	HYPH
cord-347298-7kqrl3rv	156	31	specific	specific	JJ
cord-347298-7kqrl3rv	156	32	antigens	antigen	NNS
cord-347298-7kqrl3rv	156	33	under	under	IN
cord-347298-7kqrl3rv	156	34	the	the	DT
cord-347298-7kqrl3rv	156	35	control	control	NN
cord-347298-7kqrl3rv	156	36	of	of	IN
cord-347298-7kqrl3rv	156	37	the	the	DT
cord-347298-7kqrl3rv	156	38	transcription	transcription	NN
cord-347298-7kqrl3rv	156	39	factor	factor	NN
cord-347298-7kqrl3rv	156	40	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	156	41	regulator	regulator	NN
cord-347298-7kqrl3rv	156	42	(	(	-LRB-
cord-347298-7kqrl3rv	156	43	Aire	Aire	NNP
cord-347298-7kqrl3rv	156	44	)	)	-RRB-
cord-347298-7kqrl3rv	156	45	(	(	-LRB-
cord-347298-7kqrl3rv	156	46	Liston	Liston	NNP
cord-347298-7kqrl3rv	156	47	et	et	NNP
cord-347298-7kqrl3rv	156	48	al	al	NNP
cord-347298-7kqrl3rv	156	49	.	.	NNP
cord-347298-7kqrl3rv	156	50	2003	2003	CD
cord-347298-7kqrl3rv	156	51	)	)	-RRB-
cord-347298-7kqrl3rv	156	52	.	.	.
cord-347298-7kqrl3rv	157	1	Lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	157	2	that	that	WDT
cord-347298-7kqrl3rv	157	3	recognize	recognize	VBP
cord-347298-7kqrl3rv	157	4	these	these	DT
cord-347298-7kqrl3rv	157	5	self	self	NN
cord-347298-7kqrl3rv	157	6	-	-	HYPH
cord-347298-7kqrl3rv	157	7	antigens	antigen	NNS
cord-347298-7kqrl3rv	157	8	within	within	IN
cord-347298-7kqrl3rv	157	9	the	the	DT
cord-347298-7kqrl3rv	157	10	thymus	thymus	NN
cord-347298-7kqrl3rv	157	11	during	during	IN
cord-347298-7kqrl3rv	157	12	this	this	DT
cord-347298-7kqrl3rv	157	13	process	process	NN
cord-347298-7kqrl3rv	157	14	are	be	VBP
cord-347298-7kqrl3rv	157	15	targeted	target	VBN
cord-347298-7kqrl3rv	157	16	for	for	IN
cord-347298-7kqrl3rv	157	17	destruction	destruction	NN
cord-347298-7kqrl3rv	157	18	,	,	,
cord-347298-7kqrl3rv	157	19	effectively	effectively	RB
cord-347298-7kqrl3rv	157	20	removing	remove	VBG
cord-347298-7kqrl3rv	157	21	them	-PRON-	PRP
cord-347298-7kqrl3rv	157	22	from	from	IN
cord-347298-7kqrl3rv	157	23	the	the	DT
cord-347298-7kqrl3rv	157	24	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	157	25	repertoire	repertoire	NN
cord-347298-7kqrl3rv	157	26	.	.	.
cord-347298-7kqrl3rv	158	1	In	in	IN
cord-347298-7kqrl3rv	158	2	addition	addition	NN
cord-347298-7kqrl3rv	158	3	,	,	,
cord-347298-7kqrl3rv	158	4	there	there	EX
cord-347298-7kqrl3rv	158	5	are	be	VBP
cord-347298-7kqrl3rv	158	6	a	a	DT
cord-347298-7kqrl3rv	158	7	number	number	NN
cord-347298-7kqrl3rv	158	8	of	of	IN
cord-347298-7kqrl3rv	158	9	complex	complex	JJ
cord-347298-7kqrl3rv	158	10	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	158	11	of	of	IN
cord-347298-7kqrl3rv	158	12	peripheral	peripheral	JJ
cord-347298-7kqrl3rv	158	13	tolerance	tolerance	NN
cord-347298-7kqrl3rv	158	14	,	,	,
cord-347298-7kqrl3rv	158	15	which	which	WDT
cord-347298-7kqrl3rv	158	16	involve	involve	VBP
cord-347298-7kqrl3rv	158	17	the	the	DT
cord-347298-7kqrl3rv	158	18	inactivation	inactivation	NN
cord-347298-7kqrl3rv	158	19	of	of	IN
cord-347298-7kqrl3rv	158	20	antigen	antigen	NN
cord-347298-7kqrl3rv	158	21	-	-	HYPH
cord-347298-7kqrl3rv	158	22	specific	specific	JJ
cord-347298-7kqrl3rv	158	23	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	158	24	in	in	IN
cord-347298-7kqrl3rv	158	25	peripheral	peripheral	JJ
cord-347298-7kqrl3rv	158	26	lymphoid	lymphoid	JJ
cord-347298-7kqrl3rv	158	27	organs	organ	NNS
cord-347298-7kqrl3rv	158	28	by	by	IN
cord-347298-7kqrl3rv	158	29	weak	weak	JJ
cord-347298-7kqrl3rv	158	30	antigen	antigen	NN
cord-347298-7kqrl3rv	158	31	stimulation	stimulation	NN
cord-347298-7kqrl3rv	158	32	in	in	IN
cord-347298-7kqrl3rv	158	33	the	the	DT
cord-347298-7kqrl3rv	158	34	absence	absence	NN
cord-347298-7kqrl3rv	158	35	of	of	IN
cord-347298-7kqrl3rv	158	36	appropriate	appropriate	JJ
cord-347298-7kqrl3rv	158	37	costimulation	costimulation	NN
cord-347298-7kqrl3rv	158	38	and	and	CC
cord-347298-7kqrl3rv	158	39	the	the	DT
cord-347298-7kqrl3rv	158	40	production	production	NN
cord-347298-7kqrl3rv	158	41	of	of	IN
cord-347298-7kqrl3rv	158	42	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	158	43	with	with	IN
cord-347298-7kqrl3rv	158	44	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	158	45	activities	activity	NNS
cord-347298-7kqrl3rv	158	46	(	(	-LRB-
cord-347298-7kqrl3rv	159	1	Gilliet	Gilliet	NNP
cord-347298-7kqrl3rv	159	2	and	and	CC
cord-347298-7kqrl3rv	159	3	Liu	Liu	NNP
cord-347298-7kqrl3rv	159	4	2002	2002	CD
cord-347298-7kqrl3rv	159	5	;	;	:
cord-347298-7kqrl3rv	159	6	Piccirillo	Piccirillo	NNP
cord-347298-7kqrl3rv	159	7	and	and	CC
cord-347298-7kqrl3rv	159	8	Thornton	Thornton	NNP
cord-347298-7kqrl3rv	159	9	2004	2004	CD
cord-347298-7kqrl3rv	159	10	;	;	:
cord-347298-7kqrl3rv	159	11	Thompson	Thompson	NNP
cord-347298-7kqrl3rv	159	12	and	and	CC
cord-347298-7kqrl3rv	159	13	Thomas	Thomas	NNP
cord-347298-7kqrl3rv	159	14	2002	2002	CD
cord-347298-7kqrl3rv	159	15	)	)	-RRB-
cord-347298-7kqrl3rv	159	16	.	.	.
cord-347298-7kqrl3rv	160	1	Peripheral	peripheral	JJ
cord-347298-7kqrl3rv	160	2	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	160	3	involves	involve	VBZ
cord-347298-7kqrl3rv	160	4	several	several	JJ
cord-347298-7kqrl3rv	160	5	antigen	antigen	NN
cord-347298-7kqrl3rv	160	6	-	-	HYPH
cord-347298-7kqrl3rv	160	7	specific	specific	JJ
cord-347298-7kqrl3rv	160	8	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	160	9	or	or	CC
cord-347298-7kqrl3rv	160	10	suppressor	suppressor	NN
cord-347298-7kqrl3rv	160	11	T	t	NN
cord-347298-7kqrl3rv	160	12	cell	cell	NN
cord-347298-7kqrl3rv	160	13	types	type	NNS
cord-347298-7kqrl3rv	160	14	,	,	,
cord-347298-7kqrl3rv	161	1	most	most	RBS
cord-347298-7kqrl3rv	161	2	notably	notably	RB
cord-347298-7kqrl3rv	161	3	the	the	DT
cord-347298-7kqrl3rv	161	4	CD4	CD4	NNP
cord-347298-7kqrl3rv	161	5	þ	þ	NNP
cord-347298-7kqrl3rv	161	6	CD25	CD25	NNP
cord-347298-7kqrl3rv	161	7	þ	þ	NNP
cord-347298-7kqrl3rv	161	8	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	161	9	T	t	NN
cord-347298-7kqrl3rv	161	10	cell	cell	NN
cord-347298-7kqrl3rv	161	11	(	(	-LRB-
cord-347298-7kqrl3rv	161	12	T	T	NNP
cord-347298-7kqrl3rv	161	13	reg	reg	NNP
cord-347298-7kqrl3rv	161	14	)	)	-RRB-
cord-347298-7kqrl3rv	161	15	subset	subset	VBN
cord-347298-7kqrl3rv	161	16	.	.	.
cord-347298-7kqrl3rv	162	1	These	these	DT
cord-347298-7kqrl3rv	162	2	cells	cell	NNS
cord-347298-7kqrl3rv	162	3	selectively	selectively	RB
cord-347298-7kqrl3rv	162	4	produce	produce	VBP
cord-347298-7kqrl3rv	162	5	the	the	DT
cord-347298-7kqrl3rv	162	6	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	162	7	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	162	8	transforming	transform	VBG
cord-347298-7kqrl3rv	162	9	growth	growth	NN
cord-347298-7kqrl3rv	162	10	factor	factor	NN
cord-347298-7kqrl3rv	162	11	(	(	-LRB-
cord-347298-7kqrl3rv	162	12	TGF	TGF	NNP
cord-347298-7kqrl3rv	162	13	)	)	-RRB-
cord-347298-7kqrl3rv	162	14	and	and	CC
cord-347298-7kqrl3rv	162	15	IL10	IL10	NNP
cord-347298-7kqrl3rv	162	16	,	,	,
cord-347298-7kqrl3rv	162	17	but	but	CC
cord-347298-7kqrl3rv	162	18	also	also	RB
cord-347298-7kqrl3rv	162	19	appear	appear	VB
cord-347298-7kqrl3rv	162	20	to	to	TO
cord-347298-7kqrl3rv	162	21	act	act	VB
cord-347298-7kqrl3rv	162	22	via	via	IN
cord-347298-7kqrl3rv	162	23	direct	direct	JJ
cord-347298-7kqrl3rv	162	24	contact	contact	NN
cord-347298-7kqrl3rv	162	25	with	with	IN
cord-347298-7kqrl3rv	162	26	the	the	DT
cord-347298-7kqrl3rv	162	27	cell	cell	NN
cord-347298-7kqrl3rv	162	28	being	be	VBG
cord-347298-7kqrl3rv	162	29	suppressed	suppress	VBN
cord-347298-7kqrl3rv	163	1	(	(	-LRB-
cord-347298-7kqrl3rv	163	2	Nakamura	Nakamura	NNP
cord-347298-7kqrl3rv	163	3	et	et	NNP
cord-347298-7kqrl3rv	163	4	al	al	NNP
cord-347298-7kqrl3rv	163	5	.	.	.
cord-347298-7kqrl3rv	164	1	2001	2001	CD
cord-347298-7kqrl3rv	164	2	;	;	:
cord-347298-7kqrl3rv	164	3	Piccirillo	Piccirillo	NNP
cord-347298-7kqrl3rv	164	4	et	et	NNP
cord-347298-7kqrl3rv	164	5	al	al	NNP
cord-347298-7kqrl3rv	164	6	.	.	.
cord-347298-7kqrl3rv	164	7	2002	2002	CD
cord-347298-7kqrl3rv	164	8	)	)	-RRB-
cord-347298-7kqrl3rv	164	9	.	.	.
cord-347298-7kqrl3rv	165	1	Other	other	JJ
cord-347298-7kqrl3rv	165	2	T	T	NNP
cord-347298-7kqrl3rv	165	3	cell	cell	NN
cord-347298-7kqrl3rv	165	4	subsets	subset	NNS
cord-347298-7kqrl3rv	165	5	implicated	implicate	VBN
cord-347298-7kqrl3rv	165	6	in	in	IN
cord-347298-7kqrl3rv	165	7	immunosuppression	immunosuppression	NN
cord-347298-7kqrl3rv	165	8	through	through	IN
cord-347298-7kqrl3rv	165	9	their	-PRON-	PRP$
cord-347298-7kqrl3rv	165	10	ability	ability	NN
cord-347298-7kqrl3rv	165	11	to	to	TO
cord-347298-7kqrl3rv	165	12	produce	produce	VB
cord-347298-7kqrl3rv	165	13	TGF	TGF	NNP
cord-347298-7kqrl3rv	165	14	and	and	CC
cord-347298-7kqrl3rv	165	15	IL10	IL10	NNP
cord-347298-7kqrl3rv	165	16	include	include	VBP
cord-347298-7kqrl3rv	165	17	Th3	th3	NN
cord-347298-7kqrl3rv	165	18	cells	cell	NNS
cord-347298-7kqrl3rv	165	19	,	,	,
cord-347298-7kqrl3rv	165	20	Tr1	Tr1	NNP
cord-347298-7kqrl3rv	165	21	(	(	-LRB-
cord-347298-7kqrl3rv	165	22	T	T	NNP
cord-347298-7kqrl3rv	165	23	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	165	24	1	1	CD
cord-347298-7kqrl3rv	165	25	)	)	-RRB-
cord-347298-7kqrl3rv	165	26	cells	cell	NNS
cord-347298-7kqrl3rv	165	27	,	,	,
cord-347298-7kqrl3rv	165	28	and	and	CC
cord-347298-7kqrl3rv	165	29	T	t	NN
cord-347298-7kqrl3rv	165	30	cells	cell	NNS
cord-347298-7kqrl3rv	165	31	,	,	,
cord-347298-7kqrl3rv	166	1	the	the	DT
cord-347298-7kqrl3rv	166	2	latter	latter	JJ
cord-347298-7kqrl3rv	166	3	being	be	VBG
cord-347298-7kqrl3rv	166	4	a	a	DT
cord-347298-7kqrl3rv	166	5	minor	minor	JJ
cord-347298-7kqrl3rv	166	6	T	t	NN
cord-347298-7kqrl3rv	166	7	cell	cell	NN
cord-347298-7kqrl3rv	166	8	subset	subset	NN
cord-347298-7kqrl3rv	166	9	that	that	WDT
cord-347298-7kqrl3rv	166	10	is	be	VBZ
cord-347298-7kqrl3rv	166	11	generally	generally	RB
cord-347298-7kqrl3rv	166	12	associated	associate	VBN
cord-347298-7kqrl3rv	166	13	with	with	IN
cord-347298-7kqrl3rv	166	14	epithelia	epithelium	NNS
cord-347298-7kqrl3rv	166	15	(	(	-LRB-
cord-347298-7kqrl3rv	166	16	Kuhnlein	Kuhnlein	NNP
cord-347298-7kqrl3rv	166	17	et	et	FW
cord-347298-7kqrl3rv	166	18	al	al	NNP
cord-347298-7kqrl3rv	166	19	.	.	.
cord-347298-7kqrl3rv	166	20	1994	1994	CD
cord-347298-7kqrl3rv	166	21	;	;	:
cord-347298-7kqrl3rv	166	22	MacDonald	MacDonald	NNP
cord-347298-7kqrl3rv	166	23	1998	1998	CD
cord-347298-7kqrl3rv	166	24	;	;	:
cord-347298-7kqrl3rv	167	1	Seo	Seo	NNP
cord-347298-7kqrl3rv	167	2	et	et	NNP
cord-347298-7kqrl3rv	167	3	al	al	NNP
cord-347298-7kqrl3rv	167	4	.	.	NNP
cord-347298-7kqrl3rv	167	5	2001	2001	CD
cord-347298-7kqrl3rv	167	6	)	)	-RRB-
cord-347298-7kqrl3rv	167	7	.	.	.
cord-347298-7kqrl3rv	168	1	The	the	DT
cord-347298-7kqrl3rv	168	2	NKT	NKT	NNP
cord-347298-7kqrl3rv	168	3	cells	cell	NNS
cord-347298-7kqrl3rv	168	4	,	,	,
cord-347298-7kqrl3rv	168	5	which	which	WDT
cord-347298-7kqrl3rv	168	6	are	be	VBP
cord-347298-7kqrl3rv	168	7	T	T	NNP
cord-347298-7kqrl3rv	168	8	cells	cell	NNS
cord-347298-7kqrl3rv	168	9	with	with	IN
cord-347298-7kqrl3rv	168	10	NK	NK	NNP
cord-347298-7kqrl3rv	168	11	activity	activity	NN
cord-347298-7kqrl3rv	168	12	that	that	WDT
cord-347298-7kqrl3rv	168	13	possess	possess	VBP
cord-347298-7kqrl3rv	168	14	unique	unique	JJ
cord-347298-7kqrl3rv	168	15	restriction	restriction	NN
cord-347298-7kqrl3rv	168	16	to	to	IN
cord-347298-7kqrl3rv	168	17	glycolipid	glycolipid	NNP
cord-347298-7kqrl3rv	168	18	antigens	antigen	NNS
cord-347298-7kqrl3rv	168	19	presented	present	VBN
cord-347298-7kqrl3rv	168	20	by	by	IN
cord-347298-7kqrl3rv	168	21	the	the	DT
cord-347298-7kqrl3rv	168	22	MHC	MHC	NNP
cord-347298-7kqrl3rv	168	23	-	-	HYPH
cord-347298-7kqrl3rv	168	24	like	like	JJ
cord-347298-7kqrl3rv	168	25	molecule	molecule	NN
cord-347298-7kqrl3rv	168	26	CD1d	CD1d	NNP
cord-347298-7kqrl3rv	168	27	,	,	,
cord-347298-7kqrl3rv	168	28	play	play	VB
cord-347298-7kqrl3rv	168	29	a	a	DT
cord-347298-7kqrl3rv	168	30	role	role	NN
cord-347298-7kqrl3rv	168	31	in	in	IN
cord-347298-7kqrl3rv	168	32	promoting	promote	VBG
cord-347298-7kqrl3rv	168	33	graft	graft	NN
cord-347298-7kqrl3rv	168	34	survival	survival	NN
cord-347298-7kqrl3rv	168	35	and	and	CC
cord-347298-7kqrl3rv	168	36	development	development	NN
cord-347298-7kqrl3rv	168	37	of	of	IN
cord-347298-7kqrl3rv	168	38	CD8	CD8	NNP
cord-347298-7kqrl3rv	168	39	þ	þ	NNP
cord-347298-7kqrl3rv	168	40	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	168	41	/	/	SYM
cord-347298-7kqrl3rv	168	42	suppressor	suppressor	NN
cord-347298-7kqrl3rv	168	43	T	t	NN
cord-347298-7kqrl3rv	168	44	cells	cell	NNS
cord-347298-7kqrl3rv	168	45	through	through	IN
cord-347298-7kqrl3rv	168	46	production	production	NN
cord-347298-7kqrl3rv	168	47	of	of	IN
cord-347298-7kqrl3rv	168	48	IL4	il4	NN
cord-347298-7kqrl3rv	168	49	and	and	CC
cord-347298-7kqrl3rv	168	50	IL10	IL10	NNP
cord-347298-7kqrl3rv	168	51	(	(	-LRB-
cord-347298-7kqrl3rv	168	52	Godfrey	Godfrey	NNP
cord-347298-7kqrl3rv	168	53	et	et	NNP
cord-347298-7kqrl3rv	168	54	al	al	NNP
cord-347298-7kqrl3rv	168	55	.	.	.
cord-347298-7kqrl3rv	169	1	2000	2000	CD
cord-347298-7kqrl3rv	169	2	;	;	:
cord-347298-7kqrl3rv	169	3	Nakamura	Nakamura	NNP
cord-347298-7kqrl3rv	169	4	et	et	NNP
cord-347298-7kqrl3rv	169	5	al	al	NNP
cord-347298-7kqrl3rv	169	6	.	.	.
cord-347298-7kqrl3rv	170	1	2003	2003	CD
cord-347298-7kqrl3rv	170	2	;	;	:
cord-347298-7kqrl3rv	170	3	Sonoda	Sonoda	NNP
cord-347298-7kqrl3rv	170	4	et	et	NNP
cord-347298-7kqrl3rv	170	5	al	al	NNP
cord-347298-7kqrl3rv	170	6	.	.	NNP
cord-347298-7kqrl3rv	170	7	2001	2001	CD
cord-347298-7kqrl3rv	170	8	)	)	-RRB-
cord-347298-7kqrl3rv	170	9	.	.	.
cord-347298-7kqrl3rv	171	1	The	the	DT
cord-347298-7kqrl3rv	171	2	frontline	frontline	JJ
cord-347298-7kqrl3rv	171	3	NK	NK	NNP
cord-347298-7kqrl3rv	171	4	cells	cell	NNS
cord-347298-7kqrl3rv	171	5	are	be	VBP
cord-347298-7kqrl3rv	171	6	able	able	JJ
cord-347298-7kqrl3rv	171	7	to	to	TO
cord-347298-7kqrl3rv	171	8	modulate	modulate	VB
cord-347298-7kqrl3rv	171	9	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	171	10	immune	immune	JJ
cord-347298-7kqrl3rv	171	11	responses	response	NNS
cord-347298-7kqrl3rv	171	12	by	by	IN
cord-347298-7kqrl3rv	171	13	inducing	induce	VBG
cord-347298-7kqrl3rv	171	14	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	171	15	cell	cell	NN
cord-347298-7kqrl3rv	171	16	death	death	NN
cord-347298-7kqrl3rv	171	17	through	through	IN
cord-347298-7kqrl3rv	171	18	contact	contact	NN
cord-347298-7kqrl3rv	171	19	-	-	HYPH
cord-347298-7kqrl3rv	171	20	mediated	mediate	VBN
cord-347298-7kqrl3rv	171	21	lysis	lysis	NN
cord-347298-7kqrl3rv	171	22	,	,	,
cord-347298-7kqrl3rv	171	23	but	but	CC
cord-347298-7kqrl3rv	171	24	are	be	VBP
cord-347298-7kqrl3rv	171	25	also	also	RB
cord-347298-7kqrl3rv	171	26	capable	capable	JJ
cord-347298-7kqrl3rv	171	27	of	of	IN
cord-347298-7kqrl3rv	171	28	producing	produce	VBG
cord-347298-7kqrl3rv	171	29	IFN	IFN	NNP
cord-347298-7kqrl3rv	171	30	to	to	TO
cord-347298-7kqrl3rv	171	31	stimulate	stimulate	VB
cord-347298-7kqrl3rv	171	32	the	the	DT
cord-347298-7kqrl3rv	171	33	antigen	antigen	NN
cord-347298-7kqrl3rv	171	34	-	-	HYPH
cord-347298-7kqrl3rv	171	35	presenting	present	VBG
cord-347298-7kqrl3rv	171	36	activity	activity	NN
cord-347298-7kqrl3rv	171	37	of	of	IN
cord-347298-7kqrl3rv	171	38	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	171	39	cells	cell	NNS
cord-347298-7kqrl3rv	171	40	(	(	-LRB-
cord-347298-7kqrl3rv	171	41	Laouar	Laouar	NNP
cord-347298-7kqrl3rv	171	42	et	et	NNP
cord-347298-7kqrl3rv	171	43	al	al	NNP
cord-347298-7kqrl3rv	171	44	.	.	.
cord-347298-7kqrl3rv	172	1	2005	2005	CD
cord-347298-7kqrl3rv	172	2	;	;	:
cord-347298-7kqrl3rv	172	3	Raulet	Raulet	NNP
cord-347298-7kqrl3rv	172	4	2004	2004	CD
cord-347298-7kqrl3rv	172	5	)	)	-RRB-
cord-347298-7kqrl3rv	172	6	.	.	.
cord-347298-7kqrl3rv	173	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	173	2	is	be	VBZ
cord-347298-7kqrl3rv	173	3	the	the	DT
cord-347298-7kqrl3rv	173	4	absence	absence	NN
cord-347298-7kqrl3rv	173	5	of	of	IN
cord-347298-7kqrl3rv	173	6	tolerance	tolerance	NN
cord-347298-7kqrl3rv	173	7	that	that	WDT
cord-347298-7kqrl3rv	173	8	inhibits	inhibit	VBZ
cord-347298-7kqrl3rv	173	9	graft	graft	NN
cord-347298-7kqrl3rv	173	10	success	success	NN
cord-347298-7kqrl3rv	173	11	in	in	IN
cord-347298-7kqrl3rv	173	12	the	the	DT
cord-347298-7kqrl3rv	173	13	very	very	RB
cord-347298-7kqrl3rv	173	14	artificial	artificial	JJ
cord-347298-7kqrl3rv	173	15	condition	condition	NN
cord-347298-7kqrl3rv	173	16	of	of	IN
cord-347298-7kqrl3rv	173	17	tissue	tissue	NN
cord-347298-7kqrl3rv	173	18	transplantation	transplantation	NN
cord-347298-7kqrl3rv	173	19	.	.	.
cord-347298-7kqrl3rv	174	1	The	the	DT
cord-347298-7kqrl3rv	174	2	immune	immune	JJ
cord-347298-7kqrl3rv	174	3	cells	cell	NNS
cord-347298-7kqrl3rv	174	4	of	of	IN
cord-347298-7kqrl3rv	174	5	both	both	CC
cord-347298-7kqrl3rv	174	6	the	the	DT
cord-347298-7kqrl3rv	174	7	graft	graft	NN
cord-347298-7kqrl3rv	174	8	recipient	recipient	NN
cord-347298-7kqrl3rv	174	9	and	and	CC
cord-347298-7kqrl3rv	174	10	the	the	DT
cord-347298-7kqrl3rv	174	11	donor	donor	NN
cord-347298-7kqrl3rv	174	12	tissue	tissue	NN
cord-347298-7kqrl3rv	174	13	respond	respond	VB
cord-347298-7kqrl3rv	174	14	to	to	IN
cord-347298-7kqrl3rv	174	15	one	one	CD
cord-347298-7kqrl3rv	174	16	another	another	DT
cord-347298-7kqrl3rv	174	17	,	,	,
cord-347298-7kqrl3rv	174	18	particularly	particularly	RB
cord-347298-7kqrl3rv	174	19	with	with	IN
cord-347298-7kqrl3rv	174	20	respect	respect	NN
cord-347298-7kqrl3rv	174	21	to	to	IN
cord-347298-7kqrl3rv	174	22	polymorphic	polymorphic	JJ
cord-347298-7kqrl3rv	174	23	differences	difference	NNS
cord-347298-7kqrl3rv	174	24	of	of	IN
cord-347298-7kqrl3rv	174	25	the	the	DT
cord-347298-7kqrl3rv	174	26	MHC	MHC	NNP
cord-347298-7kqrl3rv	174	27	proteins	protein	NNS
cord-347298-7kqrl3rv	174	28	,	,	,
cord-347298-7kqrl3rv	174	29	leading	lead	VBG
cord-347298-7kqrl3rv	174	30	to	to	IN
cord-347298-7kqrl3rv	174	31	rejection	rejection	NN
cord-347298-7kqrl3rv	174	32	of	of	IN
cord-347298-7kqrl3rv	174	33	tissues	tissue	NNS
cord-347298-7kqrl3rv	174	34	that	that	WDT
cord-347298-7kqrl3rv	174	35	are	be	VBP
cord-347298-7kqrl3rv	174	36	not	not	RB
cord-347298-7kqrl3rv	174	37	antigenically	antigenically	RB
cord-347298-7kqrl3rv	174	38	matched	match	VBN
cord-347298-7kqrl3rv	174	39	(	(	-LRB-
cord-347298-7kqrl3rv	174	40	Gould	Gould	NNP
cord-347298-7kqrl3rv	174	41	and	and	CC
cord-347298-7kqrl3rv	174	42	Auchincloss	Auchincloss	NNP
cord-347298-7kqrl3rv	174	43	1999	1999	CD
cord-347298-7kqrl3rv	174	44	)	)	-RRB-
cord-347298-7kqrl3rv	174	45	.	.	.
cord-347298-7kqrl3rv	175	1	Even	even	RB
cord-347298-7kqrl3rv	175	2	under	under	IN
cord-347298-7kqrl3rv	175	3	normal	normal	JJ
cord-347298-7kqrl3rv	175	4	conditions	condition	NNS
cord-347298-7kqrl3rv	175	5	,	,	,
cord-347298-7kqrl3rv	175	6	failure	failure	NN
cord-347298-7kqrl3rv	175	7	of	of	IN
cord-347298-7kqrl3rv	175	8	preexisting	preexist	VBG
cord-347298-7kqrl3rv	175	9	tolerance	tolerance	NN
cord-347298-7kqrl3rv	175	10	may	may	MD
cord-347298-7kqrl3rv	175	11	occur	occur	VB
cord-347298-7kqrl3rv	175	12	through	through	IN
cord-347298-7kqrl3rv	175	13	a	a	DT
cord-347298-7kqrl3rv	175	14	number	number	NN
cord-347298-7kqrl3rv	175	15	of	of	IN
cord-347298-7kqrl3rv	175	16	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	175	17	,	,	,
cord-347298-7kqrl3rv	175	18	leading	lead	VBG
cord-347298-7kqrl3rv	175	19	to	to	IN
cord-347298-7kqrl3rv	175	20	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	175	21	disease	disease	NN
cord-347298-7kqrl3rv	175	22	.	.	.
cord-347298-7kqrl3rv	176	1	Somatic	somatic	JJ
cord-347298-7kqrl3rv	176	2	mutation	mutation	NN
cord-347298-7kqrl3rv	176	3	of	of	IN
cord-347298-7kqrl3rv	176	4	the	the	DT
cord-347298-7kqrl3rv	176	5	antigen	antigen	NN
cord-347298-7kqrl3rv	176	6	receptor	receptor	NN
cord-347298-7kqrl3rv	176	7	expressed	express	VBN
cord-347298-7kqrl3rv	176	8	by	by	IN
cord-347298-7kqrl3rv	176	9	a	a	DT
cord-347298-7kqrl3rv	176	10	T	t	NN
cord-347298-7kqrl3rv	176	11	or	or	CC
cord-347298-7kqrl3rv	176	12	B	b	NN
cord-347298-7kqrl3rv	176	13	cell	cell	NN
cord-347298-7kqrl3rv	176	14	may	may	MD
cord-347298-7kqrl3rv	176	15	result	result	VB
cord-347298-7kqrl3rv	176	16	in	in	IN
cord-347298-7kqrl3rv	176	17	the	the	DT
cord-347298-7kqrl3rv	176	18	creation	creation	NN
cord-347298-7kqrl3rv	176	19	of	of	IN
cord-347298-7kqrl3rv	176	20	new	new	JJ
cord-347298-7kqrl3rv	176	21	self	self	NN
cord-347298-7kqrl3rv	176	22	-	-	HYPH
cord-347298-7kqrl3rv	176	23	reactive	reactive	JJ
cord-347298-7kqrl3rv	176	24	clones	clone	NNS
cord-347298-7kqrl3rv	176	25	,	,	,
cord-347298-7kqrl3rv	176	26	subverting	subvert	VBG
cord-347298-7kqrl3rv	176	27	central	central	JJ
cord-347298-7kqrl3rv	176	28	tolerance	tolerance	NN
cord-347298-7kqrl3rv	176	29	(	(	-LRB-
cord-347298-7kqrl3rv	176	30	Burrows	Burrows	NNP
cord-347298-7kqrl3rv	176	31	et	et	NNP
cord-347298-7kqrl3rv	176	32	al	al	NNP
cord-347298-7kqrl3rv	176	33	.	.	.
cord-347298-7kqrl3rv	176	34	2000	2000	CD
cord-347298-7kqrl3rv	176	35	)	)	-RRB-
cord-347298-7kqrl3rv	176	36	.	.	.
cord-347298-7kqrl3rv	177	1	Autoimmunity	Autoimmunity	NNP
cord-347298-7kqrl3rv	177	2	may	may	MD
cord-347298-7kqrl3rv	177	3	also	also	RB
cord-347298-7kqrl3rv	177	4	occur	occur	VB
cord-347298-7kqrl3rv	177	5	when	when	WRB
cord-347298-7kqrl3rv	177	6	the	the	DT
cord-347298-7kqrl3rv	177	7	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	177	8	response	response	NN
cord-347298-7kqrl3rv	177	9	to	to	IN
cord-347298-7kqrl3rv	177	10	an	an	DT
cord-347298-7kqrl3rv	177	11	infection	infection	NN
cord-347298-7kqrl3rv	177	12	damages	damage	NNS
cord-347298-7kqrl3rv	177	13	or	or	CC
cord-347298-7kqrl3rv	177	14	overwhelms	overwhelm	VBZ
cord-347298-7kqrl3rv	177	15	normal	normal	JJ
cord-347298-7kqrl3rv	177	16	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	177	17	of	of	IN
cord-347298-7kqrl3rv	177	18	self	self	NN
cord-347298-7kqrl3rv	177	19	-	-	HYPH
cord-347298-7kqrl3rv	177	20	tolerance	tolerance	NN
cord-347298-7kqrl3rv	177	21	,	,	,
cord-347298-7kqrl3rv	177	22	or	or	CC
cord-347298-7kqrl3rv	177	23	where	where	WRB
cord-347298-7kqrl3rv	177	24	the	the	DT
cord-347298-7kqrl3rv	177	25	infection	infection	NN
cord-347298-7kqrl3rv	177	26	involves	involve	VBZ
cord-347298-7kqrl3rv	177	27	organisms	organism	NNS
cord-347298-7kqrl3rv	177	28	that	that	WDT
cord-347298-7kqrl3rv	177	29	express	express	VBP
cord-347298-7kqrl3rv	177	30	antigens	antigen	NNS
cord-347298-7kqrl3rv	177	31	that	that	WDT
cord-347298-7kqrl3rv	177	32	may	may	MD
cord-347298-7kqrl3rv	177	33	cross	cross	VB
cord-347298-7kqrl3rv	177	34	-	-	VB
cord-347298-7kqrl3rv	177	35	react	react	VB
cord-347298-7kqrl3rv	177	36	with	with	IN
cord-347298-7kqrl3rv	177	37	self	self	NN
cord-347298-7kqrl3rv	177	38	-	-	HYPH
cord-347298-7kqrl3rv	177	39	antigens	antigen	NNS
cord-347298-7kqrl3rv	177	40	(	(	-LRB-
cord-347298-7kqrl3rv	177	41	molecular	molecular	JJ
cord-347298-7kqrl3rv	177	42	mimicry	mimicry	NN
cord-347298-7kqrl3rv	177	43	)	)	-RRB-
cord-347298-7kqrl3rv	178	1	(	(	-LRB-
cord-347298-7kqrl3rv	178	2	Merkler	Merkler	NNP
cord-347298-7kqrl3rv	178	3	et	et	NNP
cord-347298-7kqrl3rv	178	4	al	al	NNP
cord-347298-7kqrl3rv	178	5	.	.	.
cord-347298-7kqrl3rv	179	1	2006	2006	CD
cord-347298-7kqrl3rv	179	2	;	;	:
cord-347298-7kqrl3rv	179	3	Regner	Regner	NNP
cord-347298-7kqrl3rv	179	4	and	and	CC
cord-347298-7kqrl3rv	179	5	Lambert	Lambert	NNP
cord-347298-7kqrl3rv	179	6	2001	2001	CD
cord-347298-7kqrl3rv	179	7	)	)	-RRB-
cord-347298-7kqrl3rv	179	8	.	.	.
cord-347298-7kqrl3rv	180	1	In	in	IN
cord-347298-7kqrl3rv	180	2	addition	addition	NN
cord-347298-7kqrl3rv	180	3	to	to	IN
cord-347298-7kqrl3rv	180	4	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	180	5	-	-	HYPH
cord-347298-7kqrl3rv	180	6	mediated	mediate	VBN
cord-347298-7kqrl3rv	180	7	tolerance	tolerance	NN
cord-347298-7kqrl3rv	180	8	already	already	RB
cord-347298-7kqrl3rv	180	9	discussed	discuss	VBN
cord-347298-7kqrl3rv	180	10	,	,	,
cord-347298-7kqrl3rv	180	11	the	the	DT
cord-347298-7kqrl3rv	180	12	immune	immune	JJ
cord-347298-7kqrl3rv	180	13	system	system	NN
cord-347298-7kqrl3rv	180	14	possesses	possess	VBZ
cord-347298-7kqrl3rv	180	15	a	a	DT
cord-347298-7kqrl3rv	180	16	repertoire	repertoire	NN
cord-347298-7kqrl3rv	180	17	of	of	IN
cord-347298-7kqrl3rv	180	18	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	180	19	that	that	WDT
cord-347298-7kqrl3rv	180	20	control	control	VBP
cord-347298-7kqrl3rv	180	21	and	and	CC
cord-347298-7kqrl3rv	180	22	limit	limit	VB
cord-347298-7kqrl3rv	180	23	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	180	24	and	and	CC
cord-347298-7kqrl3rv	180	25	immune	immune	JJ
cord-347298-7kqrl3rv	180	26	responses	response	NNS
cord-347298-7kqrl3rv	180	27	once	once	IN
cord-347298-7kqrl3rv	180	28	they	-PRON-	PRP
cord-347298-7kqrl3rv	180	29	have	have	VBP
cord-347298-7kqrl3rv	180	30	commenced	commence	VBN
cord-347298-7kqrl3rv	180	31	.	.	.
cord-347298-7kqrl3rv	181	1	Inflammation	inflammation	NN
cord-347298-7kqrl3rv	181	2	triggers	trigger	VBZ
cord-347298-7kqrl3rv	181	3	the	the	DT
cord-347298-7kqrl3rv	181	4	production	production	NN
cord-347298-7kqrl3rv	181	5	by	by	IN
cord-347298-7kqrl3rv	181	6	the	the	DT
cord-347298-7kqrl3rv	181	7	adrenal	adrenal	JJ
cord-347298-7kqrl3rv	181	8	gland	gland	NN
cord-347298-7kqrl3rv	181	9	of	of	IN
cord-347298-7kqrl3rv	181	10	corticosteroids	corticosteroid	NNS
cord-347298-7kqrl3rv	181	11	,	,	,
cord-347298-7kqrl3rv	181	12	which	which	WDT
cord-347298-7kqrl3rv	181	13	inhibit	inhibit	VBP
cord-347298-7kqrl3rv	181	14	the	the	DT
cord-347298-7kqrl3rv	181	15	production	production	NN
cord-347298-7kqrl3rv	181	16	of	of	IN
cord-347298-7kqrl3rv	181	17	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	181	18	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	181	19	and	and	CC
cord-347298-7kqrl3rv	181	20	other	other	JJ
cord-347298-7kqrl3rv	181	21	immune	immune	JJ
cord-347298-7kqrl3rv	181	22	mediators	mediator	NNS
cord-347298-7kqrl3rv	181	23	,	,	,
cord-347298-7kqrl3rv	181	24	reduce	reduce	VB
cord-347298-7kqrl3rv	181	25	the	the	DT
cord-347298-7kqrl3rv	181	26	expression	expression	NN
cord-347298-7kqrl3rv	181	27	of	of	IN
cord-347298-7kqrl3rv	181	28	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	181	29	adhesion	adhesion	NN
cord-347298-7kqrl3rv	181	30	molecules	molecule	NNS
cord-347298-7kqrl3rv	181	31	,	,	,
cord-347298-7kqrl3rv	181	32	and	and	CC
cord-347298-7kqrl3rv	181	33	induce	induce	VB
cord-347298-7kqrl3rv	181	34	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	181	35	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	181	36	(	(	-LRB-
cord-347298-7kqrl3rv	181	37	Buckingham	Buckingham	NNP
cord-347298-7kqrl3rv	181	38	et	et	NNP
cord-347298-7kqrl3rv	181	39	al	al	NNP
cord-347298-7kqrl3rv	181	40	.	.	.
cord-347298-7kqrl3rv	181	41	1996	1996	CD
cord-347298-7kqrl3rv	181	42	;	;	:
cord-347298-7kqrl3rv	181	43	Kapcala	Kapcala	NNP
cord-347298-7kqrl3rv	181	44	et	et	NNP
cord-347298-7kqrl3rv	181	45	al	al	NNP
cord-347298-7kqrl3rv	181	46	.	.	NNP
cord-347298-7kqrl3rv	181	47	1995	1995	CD
cord-347298-7kqrl3rv	181	48	)	)	-RRB-
cord-347298-7kqrl3rv	181	49	.	.	.
cord-347298-7kqrl3rv	182	1	During	during	IN
cord-347298-7kqrl3rv	182	2	inflammation	inflammation	NN
cord-347298-7kqrl3rv	182	3	,	,	,
cord-347298-7kqrl3rv	182	4	immune	immune	JJ
cord-347298-7kqrl3rv	182	5	cells	cell	NNS
cord-347298-7kqrl3rv	182	6	themselves	-PRON-	PRP
cord-347298-7kqrl3rv	182	7	produce	produce	VBP
cord-347298-7kqrl3rv	182	8	anti	anti	JJ
cord-347298-7kqrl3rv	182	9	-	-	JJ
cord-347298-7kqrl3rv	182	10	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	182	11	and	and	CC
cord-347298-7kqrl3rv	182	12	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	182	13	molecules	molecule	NNS
cord-347298-7kqrl3rv	182	14	,	,	,
cord-347298-7kqrl3rv	182	15	including	include	VBG
cord-347298-7kqrl3rv	182	16	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	182	17	D	D	NNP
cord-347298-7kqrl3rv	182	18	and	and	CC
cord-347298-7kqrl3rv	182	19	J	J	NNP
cord-347298-7kqrl3rv	182	20	and	and	CC
cord-347298-7kqrl3rv	182	21	the	the	DT
cord-347298-7kqrl3rv	182	22	lipoxins	lipoxin	NNS
cord-347298-7kqrl3rv	182	23	(	(	-LRB-
cord-347298-7kqrl3rv	182	24	Herlong	Herlong	NNP
cord-347298-7kqrl3rv	182	25	and	and	CC
cord-347298-7kqrl3rv	182	26	Scott	Scott	NNP
cord-347298-7kqrl3rv	182	27	2006	2006	CD
cord-347298-7kqrl3rv	182	28	;	;	:
cord-347298-7kqrl3rv	182	29	Levy	Levy	NNP
cord-347298-7kqrl3rv	182	30	et	et	NNP
cord-347298-7kqrl3rv	182	31	al	al	NNP
cord-347298-7kqrl3rv	182	32	.	.	NNP
cord-347298-7kqrl3rv	182	33	2001	2001	CD
cord-347298-7kqrl3rv	182	34	)	)	-RRB-
cord-347298-7kqrl3rv	182	35	.	.	.
cord-347298-7kqrl3rv	183	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	183	2	,	,	,
cord-347298-7kqrl3rv	183	3	activated	activate	VBN
cord-347298-7kqrl3rv	183	4	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	183	5	have	have	VBP
cord-347298-7kqrl3rv	183	6	a	a	DT
cord-347298-7kqrl3rv	183	7	limited	limited	JJ
cord-347298-7kqrl3rv	183	8	lifespan	lifespan	NN
cord-347298-7kqrl3rv	183	9	,	,	,
cord-347298-7kqrl3rv	183	10	undergoing	undergo	VBG
cord-347298-7kqrl3rv	183	11	a	a	DT
cord-347298-7kqrl3rv	183	12	process	process	NN
cord-347298-7kqrl3rv	183	13	of	of	IN
cord-347298-7kqrl3rv	183	14	activation	activation	NN
cord-347298-7kqrl3rv	183	15	-	-	HYPH
cord-347298-7kqrl3rv	183	16	induced	induce	VBN
cord-347298-7kqrl3rv	183	17	cell	cell	NN
cord-347298-7kqrl3rv	183	18	death	death	NN
cord-347298-7kqrl3rv	183	19	following	follow	VBG
cord-347298-7kqrl3rv	183	20	upregulation	upregulation	NN
cord-347298-7kqrl3rv	183	21	of	of	IN
cord-347298-7kqrl3rv	183	22	the	the	DT
cord-347298-7kqrl3rv	183	23	extrinsic	extrinsic	JJ
cord-347298-7kqrl3rv	183	24	apoptotic	apoptotic	JJ
cord-347298-7kqrl3rv	183	25	signal	signal	NN
cord-347298-7kqrl3rv	183	26	mediated	mediate	VBN
cord-347298-7kqrl3rv	183	27	by	by	IN
cord-347298-7kqrl3rv	183	28	interaction	interaction	NN
cord-347298-7kqrl3rv	183	29	of	of	IN
cord-347298-7kqrl3rv	183	30	the	the	DT
cord-347298-7kqrl3rv	183	31	Fas	Fas	NNP
cord-347298-7kqrl3rv	183	32	receptor	receptor	NN
cord-347298-7kqrl3rv	183	33	(	(	-LRB-
cord-347298-7kqrl3rv	183	34	CD95	CD95	NNP
cord-347298-7kqrl3rv	183	35	)	)	-RRB-
cord-347298-7kqrl3rv	183	36	with	with	IN
cord-347298-7kqrl3rv	183	37	its	-PRON-	PRP$
cord-347298-7kqrl3rv	183	38	ligand	ligand	NN
cord-347298-7kqrl3rv	183	39	(	(	-LRB-
cord-347298-7kqrl3rv	183	40	Fas	Fas	NNP
cord-347298-7kqrl3rv	183	41	ligand	ligand	NN
cord-347298-7kqrl3rv	183	42	:	:	:
cord-347298-7kqrl3rv	183	43	FasL	FasL	NNP
cord-347298-7kqrl3rv	183	44	or	or	CC
cord-347298-7kqrl3rv	183	45	CD95L	CD95L	NNP
cord-347298-7kqrl3rv	183	46	)	)	-RRB-
cord-347298-7kqrl3rv	183	47	,	,	,
cord-347298-7kqrl3rv	183	48	eventually	eventually	RB
cord-347298-7kqrl3rv	183	49	leaving	leave	VBG
cord-347298-7kqrl3rv	183	50	behind	behind	RB
cord-347298-7kqrl3rv	183	51	a	a	DT
cord-347298-7kqrl3rv	183	52	relatively	relatively	RB
cord-347298-7kqrl3rv	183	53	small	small	JJ
cord-347298-7kqrl3rv	183	54	number	number	NN
cord-347298-7kqrl3rv	183	55	of	of	IN
cord-347298-7kqrl3rv	183	56	long	long	RB
cord-347298-7kqrl3rv	183	57	-	-	HYPH
cord-347298-7kqrl3rv	183	58	lived	live	VBN
cord-347298-7kqrl3rv	183	59	memory	memory	NN
cord-347298-7kqrl3rv	183	60	cells	cell	NNS
cord-347298-7kqrl3rv	183	61	(	(	-LRB-
cord-347298-7kqrl3rv	183	62	Dutton	Dutton	NNP
cord-347298-7kqrl3rv	183	63	et	et	NNP
cord-347298-7kqrl3rv	183	64	al	al	NNP
cord-347298-7kqrl3rv	183	65	.	.	.
cord-347298-7kqrl3rv	184	1	1998	1998	CD
cord-347298-7kqrl3rv	184	2	;	;	:
cord-347298-7kqrl3rv	184	3	Schittek	Schittek	NNP
cord-347298-7kqrl3rv	184	4	and	and	CC
cord-347298-7kqrl3rv	184	5	Rajewsky	Rajewsky	NNP
cord-347298-7kqrl3rv	184	6	1990	1990	CD
cord-347298-7kqrl3rv	184	7	)	)	-RRB-
cord-347298-7kqrl3rv	184	8	.	.	.
cord-347298-7kqrl3rv	185	1	Likewise	likewise	RB
cord-347298-7kqrl3rv	185	2	,	,	,
cord-347298-7kqrl3rv	185	3	there	there	EX
cord-347298-7kqrl3rv	185	4	are	be	VBP
cord-347298-7kqrl3rv	185	5	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	185	6	to	to	TO
cord-347298-7kqrl3rv	185	7	inhibit	inhibit	VB
cord-347298-7kqrl3rv	185	8	antibody	antibody	NN
cord-347298-7kqrl3rv	185	9	activity	activity	NN
cord-347298-7kqrl3rv	185	10	and	and	CC
cord-347298-7kqrl3rv	185	11	promote	promote	VB
cord-347298-7kqrl3rv	185	12	antibody	antibody	NN
cord-347298-7kqrl3rv	185	13	clearance	clearance	NN
cord-347298-7kqrl3rv	185	14	(	(	-LRB-
cord-347298-7kqrl3rv	185	15	Isaacs	Isaacs	NNP
cord-347298-7kqrl3rv	185	16	1990	1990	CD
cord-347298-7kqrl3rv	185	17	)	)	-RRB-
cord-347298-7kqrl3rv	185	18	.	.	.
cord-347298-7kqrl3rv	186	1	Classically	classically	RB
cord-347298-7kqrl3rv	186	2	,	,	,
cord-347298-7kqrl3rv	186	3	the	the	DT
cord-347298-7kqrl3rv	186	4	term	term	NN
cord-347298-7kqrl3rv	186	5	immune	immune	JJ
cord-347298-7kqrl3rv	186	6	privilege	privilege	NN
cord-347298-7kqrl3rv	186	7	applies	apply	VBZ
cord-347298-7kqrl3rv	186	8	to	to	IN
cord-347298-7kqrl3rv	186	9	organs	organ	NNS
cord-347298-7kqrl3rv	186	10	or	or	CC
cord-347298-7kqrl3rv	186	11	tissues	tissue	NNS
cord-347298-7kqrl3rv	186	12	where	where	WRB
cord-347298-7kqrl3rv	186	13	survival	survival	NN
cord-347298-7kqrl3rv	186	14	of	of	IN
cord-347298-7kqrl3rv	186	15	foreign	foreign	JJ
cord-347298-7kqrl3rv	186	16	grafts	graft	NNS
cord-347298-7kqrl3rv	186	17	may	may	MD
cord-347298-7kqrl3rv	186	18	be	be	VB
cord-347298-7kqrl3rv	186	19	prolonged	prolong	VBN
cord-347298-7kqrl3rv	187	1	(	(	-LRB-
cord-347298-7kqrl3rv	187	2	Barker	Barker	NNP
cord-347298-7kqrl3rv	187	3	and	and	CC
cord-347298-7kqrl3rv	187	4	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	187	5	1977	1977	CD
cord-347298-7kqrl3rv	187	6	)	)	-RRB-
cord-347298-7kqrl3rv	187	7	,	,	,
cord-347298-7kqrl3rv	187	8	but	but	CC
cord-347298-7kqrl3rv	187	9	more	more	RBR
cord-347298-7kqrl3rv	187	10	accurately	accurately	RB
cord-347298-7kqrl3rv	187	11	,	,	,
cord-347298-7kqrl3rv	187	12	the	the	DT
cord-347298-7kqrl3rv	187	13	term	term	NN
cord-347298-7kqrl3rv	187	14	denotes	denote	VBZ
cord-347298-7kqrl3rv	187	15	tissues	tissue	NNS
cord-347298-7kqrl3rv	187	16	where	where	WRB
cord-347298-7kqrl3rv	187	17	immune	immune	JJ
cord-347298-7kqrl3rv	187	18	responses	response	NNS
cord-347298-7kqrl3rv	187	19	are	be	VBP
cord-347298-7kqrl3rv	187	20	inhibited	inhibit	VBN
cord-347298-7kqrl3rv	187	21	or	or	CC
cord-347298-7kqrl3rv	187	22	suppressed	suppress	VBN
cord-347298-7kqrl3rv	187	23	(	(	-LRB-
cord-347298-7kqrl3rv	187	24	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	187	25	2007	2007	CD
cord-347298-7kqrl3rv	187	26	)	)	-RRB-
cord-347298-7kqrl3rv	187	27	.	.	.
cord-347298-7kqrl3rv	188	1	Privileged	privileged	JJ
cord-347298-7kqrl3rv	188	2	tissues	tissue	NNS
cord-347298-7kqrl3rv	188	3	include	include	VBP
cord-347298-7kqrl3rv	188	4	the	the	DT
cord-347298-7kqrl3rv	188	5	brain	brain	NN
cord-347298-7kqrl3rv	188	6	,	,	,
cord-347298-7kqrl3rv	188	7	eye	eye	NN
cord-347298-7kqrl3rv	188	8	,	,	,
cord-347298-7kqrl3rv	188	9	pregnant	pregnant	JJ
cord-347298-7kqrl3rv	188	10	uterus	uterus	NN
cord-347298-7kqrl3rv	188	11	,	,	,
cord-347298-7kqrl3rv	188	12	and	and	CC
cord-347298-7kqrl3rv	188	13	the	the	DT
cord-347298-7kqrl3rv	188	14	testis	testis	NN
cord-347298-7kqrl3rv	188	15	.	.	.
cord-347298-7kqrl3rv	189	1	Initially	initially	RB
cord-347298-7kqrl3rv	189	2	,	,	,
cord-347298-7kqrl3rv	189	3	privilege	privilege	NN
cord-347298-7kqrl3rv	189	4	was	be	VBD
cord-347298-7kqrl3rv	189	5	attributed	attribute	VBN
cord-347298-7kqrl3rv	189	6	to	to	IN
cord-347298-7kqrl3rv	189	7	deficient	deficient	JJ
cord-347298-7kqrl3rv	189	8	lymphatic	lymphatic	JJ
cord-347298-7kqrl3rv	189	9	drainage	drainage	NN
cord-347298-7kqrl3rv	189	10	in	in	IN
cord-347298-7kqrl3rv	189	11	such	such	JJ
cord-347298-7kqrl3rv	189	12	tissues	tissue	NNS
cord-347298-7kqrl3rv	189	13	,	,	,
cord-347298-7kqrl3rv	189	14	or	or	CC
cord-347298-7kqrl3rv	189	15	physical	physical	JJ
cord-347298-7kqrl3rv	189	16	barriers	barrier	NNS
cord-347298-7kqrl3rv	189	17	that	that	WDT
cord-347298-7kqrl3rv	189	18	prevented	prevent	VBD
cord-347298-7kqrl3rv	189	19	immune	immune	JJ
cord-347298-7kqrl3rv	189	20	cells	cell	NNS
cord-347298-7kqrl3rv	189	21	from	from	IN
cord-347298-7kqrl3rv	189	22	gaining	gain	VBG
cord-347298-7kqrl3rv	189	23	access	access	NN
cord-347298-7kqrl3rv	189	24	(	(	-LRB-
cord-347298-7kqrl3rv	189	25	Barker	Barker	NNP
cord-347298-7kqrl3rv	189	26	and	and	CC
cord-347298-7kqrl3rv	189	27	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	189	28	1977	1977	CD
cord-347298-7kqrl3rv	189	29	)	)	-RRB-
cord-347298-7kqrl3rv	189	30	.	.	.
cord-347298-7kqrl3rv	190	1	Several	several	JJ
cord-347298-7kqrl3rv	190	2	privileged	privileged	JJ
cord-347298-7kqrl3rv	190	3	tissues	tissue	NNS
cord-347298-7kqrl3rv	190	4	do	do	VBP
cord-347298-7kqrl3rv	190	5	possess	possess	VB
cord-347298-7kqrl3rv	190	6	highly	highly	RB
cord-347298-7kqrl3rv	190	7	specialized	specialized	JJ
cord-347298-7kqrl3rv	190	8	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	190	9	or	or	CC
cord-347298-7kqrl3rv	190	10	endothelial	endothelial	JJ
cord-347298-7kqrl3rv	190	11	cell	cell	NN
cord-347298-7kqrl3rv	190	12	barriers	barrier	NNS
cord-347298-7kqrl3rv	190	13	that	that	WDT
cord-347298-7kqrl3rv	190	14	may	may	MD
cord-347298-7kqrl3rv	190	15	sequester	sequester	VB
cord-347298-7kqrl3rv	190	16	antigens	antigen	NNS
cord-347298-7kqrl3rv	190	17	away	away	RB
cord-347298-7kqrl3rv	190	18	from	from	IN
cord-347298-7kqrl3rv	190	19	the	the	DT
cord-347298-7kqrl3rv	190	20	normal	normal	JJ
cord-347298-7kqrl3rv	190	21	immune	immune	JJ
cord-347298-7kqrl3rv	190	22	surveillance	surveillance	NN
cord-347298-7kqrl3rv	190	23	:	:	:
cord-347298-7kqrl3rv	190	24	the	the	DT
cord-347298-7kqrl3rv	190	25	best	well	RBS
cord-347298-7kqrl3rv	190	26	characterized	characterize	VBN
cord-347298-7kqrl3rv	190	27	of	of	IN
cord-347298-7kqrl3rv	190	28	these	these	DT
cord-347298-7kqrl3rv	190	29	are	be	VBP
cord-347298-7kqrl3rv	190	30	the	the	DT
cord-347298-7kqrl3rv	190	31	blood	blood	NN
cord-347298-7kqrl3rv	190	32	-	-	HYPH
cord-347298-7kqrl3rv	190	33	brain	brain	NN
cord-347298-7kqrl3rv	190	34	barrier	barrier	NN
cord-347298-7kqrl3rv	190	35	and	and	CC
cord-347298-7kqrl3rv	190	36	the	the	DT
cord-347298-7kqrl3rv	190	37	trophoblast	trophoblast	NN
cord-347298-7kqrl3rv	190	38	in	in	IN
cord-347298-7kqrl3rv	190	39	the	the	DT
cord-347298-7kqrl3rv	190	40	pregnant	pregnant	JJ
cord-347298-7kqrl3rv	190	41	uterus	uterus	NN
cord-347298-7kqrl3rv	190	42	(	(	-LRB-
cord-347298-7kqrl3rv	190	43	Hunt	hunt	NN
cord-347298-7kqrl3rv	190	44	2006	2006	CD
cord-347298-7kqrl3rv	190	45	;	;	:
cord-347298-7kqrl3rv	190	46	Streilein	Streilein	NNP
cord-347298-7kqrl3rv	190	47	1993	1993	CD
cord-347298-7kqrl3rv	190	48	)	)	-RRB-
cord-347298-7kqrl3rv	190	49	.	.	.
cord-347298-7kqrl3rv	191	1	However	however	RB
cord-347298-7kqrl3rv	191	2	,	,	,
cord-347298-7kqrl3rv	191	3	physical	physical	JJ
cord-347298-7kqrl3rv	191	4	exclusion	exclusion	NN
cord-347298-7kqrl3rv	191	5	is	be	VBZ
cord-347298-7kqrl3rv	191	6	now	now	RB
cord-347298-7kqrl3rv	191	7	considered	consider	VBN
cord-347298-7kqrl3rv	191	8	an	an	DT
cord-347298-7kqrl3rv	191	9	overly	overly	RB
cord-347298-7kqrl3rv	191	10	simplistic	simplistic	JJ
cord-347298-7kqrl3rv	191	11	explanation	explanation	NN
cord-347298-7kqrl3rv	191	12	for	for	IN
cord-347298-7kqrl3rv	191	13	immune	immune	JJ
cord-347298-7kqrl3rv	191	14	privilege	privilege	NN
cord-347298-7kqrl3rv	191	15	,	,	,
cord-347298-7kqrl3rv	191	16	given	give	VBN
cord-347298-7kqrl3rv	191	17	that	that	IN
cord-347298-7kqrl3rv	191	18	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	191	19	and	and	CC
cord-347298-7kqrl3rv	191	20	antibody	antibody	NN
cord-347298-7kqrl3rv	191	21	responses	response	NNS
cord-347298-7kqrl3rv	191	22	to	to	IN
cord-347298-7kqrl3rv	191	23	introduced	introduce	VBN
cord-347298-7kqrl3rv	191	24	antigens	antigen	NNS
cord-347298-7kqrl3rv	191	25	occur	occur	VBP
cord-347298-7kqrl3rv	191	26	even	even	RB
cord-347298-7kqrl3rv	191	27	in	in	IN
cord-347298-7kqrl3rv	191	28	sites	site	NNS
cord-347298-7kqrl3rv	191	29	where	where	WRB
cord-347298-7kqrl3rv	191	30	grafts	graft	NNS
cord-347298-7kqrl3rv	191	31	can	can	MD
cord-347298-7kqrl3rv	191	32	survive	survive	VB
cord-347298-7kqrl3rv	191	33	for	for	IN
cord-347298-7kqrl3rv	191	34	extended	extended	JJ
cord-347298-7kqrl3rv	191	35	periods	period	NNS
cord-347298-7kqrl3rv	191	36	(	(	-LRB-
cord-347298-7kqrl3rv	191	37	Head	Head	NNP
cord-347298-7kqrl3rv	191	38	et	et	NNP
cord-347298-7kqrl3rv	191	39	al	al	NNP
cord-347298-7kqrl3rv	191	40	.	.	NNP
cord-347298-7kqrl3rv	191	41	1983b	1983b	CD
cord-347298-7kqrl3rv	191	42	;	;	:
cord-347298-7kqrl3rv	191	43	Kaplan	Kaplan	NNP
cord-347298-7kqrl3rv	191	44	and	and	CC
cord-347298-7kqrl3rv	191	45	Streilein	Streilein	NNP
cord-347298-7kqrl3rv	191	46	1978	1978	CD
cord-347298-7kqrl3rv	191	47	;	;	:
cord-347298-7kqrl3rv	191	48	Tafuri	Tafuri	NNP
cord-347298-7kqrl3rv	191	49	et	et	NNP
cord-347298-7kqrl3rv	191	50	al	al	NNP
cord-347298-7kqrl3rv	191	51	.	.	NNP
cord-347298-7kqrl3rv	191	52	1995	1995	CD
cord-347298-7kqrl3rv	191	53	)	)	-RRB-
cord-347298-7kqrl3rv	191	54	.	.	.
cord-347298-7kqrl3rv	192	1	Although	although	IN
cord-347298-7kqrl3rv	192	2	barrier	barrier	NN
cord-347298-7kqrl3rv	192	3	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	192	4	and	and	CC
cord-347298-7kqrl3rv	192	5	altered	alter	VBN
cord-347298-7kqrl3rv	192	6	lymphatics	lymphatic	NNS
cord-347298-7kqrl3rv	192	7	may	may	MD
cord-347298-7kqrl3rv	192	8	be	be	VB
cord-347298-7kqrl3rv	192	9	contributory	contributory	JJ
cord-347298-7kqrl3rv	192	10	factors	factor	NNS
cord-347298-7kqrl3rv	192	11	in	in	IN
cord-347298-7kqrl3rv	192	12	some	some	DT
cord-347298-7kqrl3rv	192	13	tissues	tissue	NNS
cord-347298-7kqrl3rv	192	14	,	,	,
cord-347298-7kqrl3rv	192	15	immune	immune	JJ
cord-347298-7kqrl3rv	192	16	privilege	privilege	NN
cord-347298-7kqrl3rv	192	17	is	be	VBZ
cord-347298-7kqrl3rv	192	18	a	a	DT
cord-347298-7kqrl3rv	192	19	consequence	consequence	NN
cord-347298-7kqrl3rv	192	20	of	of	IN
cord-347298-7kqrl3rv	192	21	tissue	tissue	NN
cord-347298-7kqrl3rv	192	22	-	-	HYPH
cord-347298-7kqrl3rv	192	23	specific	specific	JJ
cord-347298-7kqrl3rv	192	24	specialized	specialized	JJ
cord-347298-7kqrl3rv	192	25	systems	system	NNS
cord-347298-7kqrl3rv	192	26	for	for	IN
cord-347298-7kqrl3rv	192	27	controlling	control	VBG
cord-347298-7kqrl3rv	192	28	,	,	,
cord-347298-7kqrl3rv	192	29	subverting	subvert	VBG
cord-347298-7kqrl3rv	192	30	,	,	,
cord-347298-7kqrl3rv	192	31	or	or	CC
cord-347298-7kqrl3rv	192	32	preventing	prevent	VBG
cord-347298-7kqrl3rv	192	33	local	local	JJ
cord-347298-7kqrl3rv	192	34	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	192	35	or	or	CC
cord-347298-7kqrl3rv	192	36	immune	immune	JJ
cord-347298-7kqrl3rv	192	37	activation	activation	NN
cord-347298-7kqrl3rv	192	38	responses	response	NNS
cord-347298-7kqrl3rv	192	39	(	(	-LRB-
cord-347298-7kqrl3rv	192	40	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	192	41	2007	2007	CD
cord-347298-7kqrl3rv	192	42	)	)	-RRB-
cord-347298-7kqrl3rv	192	43	.	.	.
cord-347298-7kqrl3rv	193	1	The	the	DT
cord-347298-7kqrl3rv	193	2	male	male	JJ
cord-347298-7kqrl3rv	193	3	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	193	4	tract	tract	NN
cord-347298-7kqrl3rv	193	5	comprises	comprise	VBZ
cord-347298-7kqrl3rv	193	6	the	the	DT
cord-347298-7kqrl3rv	193	7	paired	paired	JJ
cord-347298-7kqrl3rv	193	8	testes	testis	NNS
cord-347298-7kqrl3rv	193	9	,	,	,
cord-347298-7kqrl3rv	193	10	associated	associate	VBN
cord-347298-7kqrl3rv	193	11	epididymis	epididymis	NN
cord-347298-7kqrl3rv	193	12	and	and	CC
cord-347298-7kqrl3rv	193	13	vas	vas	NNP
cord-347298-7kqrl3rv	193	14	deferentia	deferentia	NNP
cord-347298-7kqrl3rv	193	15	,	,	,
cord-347298-7kqrl3rv	193	16	accessory	accessory	JJ
cord-347298-7kqrl3rv	193	17	glands	gland	NNS
cord-347298-7kqrl3rv	193	18	(	(	-LRB-
cord-347298-7kqrl3rv	193	19	chiefly	chiefly	RB
cord-347298-7kqrl3rv	193	20	the	the	DT
cord-347298-7kqrl3rv	193	21	prostate	prostate	NN
cord-347298-7kqrl3rv	193	22	and	and	CC
cord-347298-7kqrl3rv	193	23	seminal	seminal	JJ
cord-347298-7kqrl3rv	193	24	vesicles	vesicle	NNS
cord-347298-7kqrl3rv	193	25	)	)	-RRB-
cord-347298-7kqrl3rv	193	26	,	,	,
cord-347298-7kqrl3rv	193	27	and	and	CC
cord-347298-7kqrl3rv	193	28	the	the	DT
cord-347298-7kqrl3rv	193	29	urethra	urethra	NN
cord-347298-7kqrl3rv	193	30	.	.	.
cord-347298-7kqrl3rv	194	1	These	these	DT
cord-347298-7kqrl3rv	194	2	tissues	tissue	NNS
cord-347298-7kqrl3rv	194	3	represent	represent	VBP
cord-347298-7kqrl3rv	194	4	a	a	DT
cord-347298-7kqrl3rv	194	5	diversity	diversity	NN
cord-347298-7kqrl3rv	194	6	of	of	IN
cord-347298-7kqrl3rv	194	7	structures	structure	NNS
cord-347298-7kqrl3rv	194	8	and	and	CC
cord-347298-7kqrl3rv	194	9	,	,	,
cord-347298-7kqrl3rv	194	10	consequently	consequently	RB
cord-347298-7kqrl3rv	194	11	,	,	,
cord-347298-7kqrl3rv	194	12	the	the	DT
cord-347298-7kqrl3rv	194	13	immunology	immunology	NN
cord-347298-7kqrl3rv	194	14	of	of	IN
cord-347298-7kqrl3rv	194	15	each	each	DT
cord-347298-7kqrl3rv	194	16	tissue	tissue	NN
cord-347298-7kqrl3rv	194	17	retains	retain	VBZ
cord-347298-7kqrl3rv	194	18	distinctive	distinctive	JJ
cord-347298-7kqrl3rv	194	19	features	feature	NNS
cord-347298-7kqrl3rv	194	20	(	(	-LRB-
cord-347298-7kqrl3rv	194	21	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	194	22	and	and	CC
cord-347298-7kqrl3rv	194	23	Hales	Hales	NNP
cord-347298-7kqrl3rv	194	24	2006	2006	CD
cord-347298-7kqrl3rv	194	25	)	)	-RRB-
cord-347298-7kqrl3rv	194	26	.	.	.
cord-347298-7kqrl3rv	195	1	Best	well	RBS
cord-347298-7kqrl3rv	195	2	studied	study	VBN
cord-347298-7kqrl3rv	195	3	in	in	IN
cord-347298-7kqrl3rv	195	4	this	this	DT
cord-347298-7kqrl3rv	195	5	context	context	NN
cord-347298-7kqrl3rv	195	6	is	be	VBZ
cord-347298-7kqrl3rv	195	7	the	the	DT
cord-347298-7kqrl3rv	195	8	testis	testis	NN
cord-347298-7kqrl3rv	195	9	,	,	,
cord-347298-7kqrl3rv	195	10	which	which	WDT
cord-347298-7kqrl3rv	195	11	comprises	comprise	VBZ
cord-347298-7kqrl3rv	195	12	two	two	CD
cord-347298-7kqrl3rv	195	13	discrete	discrete	JJ
cord-347298-7kqrl3rv	195	14	tissue	tissue	NN
cord-347298-7kqrl3rv	195	15	compartments	compartment	NNS
cord-347298-7kqrl3rv	195	16	,	,	,
cord-347298-7kqrl3rv	195	17	the	the	DT
cord-347298-7kqrl3rv	195	18	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	195	19	tubules	tubule	NNS
cord-347298-7kqrl3rv	195	20	and	and	CC
cord-347298-7kqrl3rv	195	21	the	the	DT
cord-347298-7kqrl3rv	195	22	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	195	23	tissue	tissue	NN
cord-347298-7kqrl3rv	195	24	.	.	.
cord-347298-7kqrl3rv	196	1	The	the	DT
cord-347298-7kqrl3rv	196	2	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	196	3	tissue	tissue	NN
cord-347298-7kqrl3rv	196	4	contains	contain	VBZ
cord-347298-7kqrl3rv	196	5	the	the	DT
cord-347298-7kqrl3rv	196	6	blood	blood	NN
cord-347298-7kqrl3rv	196	7	supply	supply	NN
cord-347298-7kqrl3rv	196	8	and	and	CC
cord-347298-7kqrl3rv	196	9	lymphatics	lymphatic	NNS
cord-347298-7kqrl3rv	196	10	,	,	,
cord-347298-7kqrl3rv	196	11	as	as	RB
cord-347298-7kqrl3rv	196	12	well	well	RB
cord-347298-7kqrl3rv	196	13	as	as	IN
cord-347298-7kqrl3rv	196	14	the	the	DT
cord-347298-7kqrl3rv	196	15	innervation	innervation	NN
cord-347298-7kqrl3rv	196	16	of	of	IN
cord-347298-7kqrl3rv	196	17	the	the	DT
cord-347298-7kqrl3rv	196	18	testis	testis	NN
cord-347298-7kqrl3rv	196	19	(	(	-LRB-
cord-347298-7kqrl3rv	196	20	Fawcett	Fawcett	NNP
cord-347298-7kqrl3rv	196	21	et	et	FW
cord-347298-7kqrl3rv	196	22	al	al	NNP
cord-347298-7kqrl3rv	196	23	.	.	.
cord-347298-7kqrl3rv	197	1	1973	1973	CD
cord-347298-7kqrl3rv	197	2	;	;	:
cord-347298-7kqrl3rv	197	3	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	197	4	et	et	FW
cord-347298-7kqrl3rv	197	5	al	al	NNP
cord-347298-7kqrl3rv	197	6	.	.	.
cord-347298-7kqrl3rv	197	7	1994	1994	CD
cord-347298-7kqrl3rv	197	8	)	)	-RRB-
cord-347298-7kqrl3rv	197	9	.	.	.
cord-347298-7kqrl3rv	198	1	The	the	DT
cord-347298-7kqrl3rv	198	2	epithelium	epithelium	NN
cord-347298-7kqrl3rv	198	3	of	of	IN
cord-347298-7kqrl3rv	198	4	the	the	DT
cord-347298-7kqrl3rv	198	5	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	198	6	tubules	tubule	NNS
cord-347298-7kqrl3rv	198	7	is	be	VBZ
cord-347298-7kqrl3rv	198	8	entirely	entirely	RB
cord-347298-7kqrl3rv	198	9	avascular	avascular	JJ
cord-347298-7kqrl3rv	198	10	.	.	.
cord-347298-7kqrl3rv	199	1	Within	within	IN
cord-347298-7kqrl3rv	199	2	the	the	DT
cord-347298-7kqrl3rv	199	3	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	199	4	epithelium	epithelium	NN
cord-347298-7kqrl3rv	199	5	,	,	,
cord-347298-7kqrl3rv	199	6	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	199	7	is	be	VBZ
cord-347298-7kqrl3rv	199	8	supported	support	VBN
cord-347298-7kqrl3rv	199	9	and	and	CC
cord-347298-7kqrl3rv	199	10	maintained	maintain	VBN
cord-347298-7kqrl3rv	199	11	by	by	IN
cord-347298-7kqrl3rv	199	12	the	the	DT
cord-347298-7kqrl3rv	199	13	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	199	14	cells	cell	NNS
cord-347298-7kqrl3rv	199	15	,	,	,
cord-347298-7kqrl3rv	199	16	which	which	WDT
cord-347298-7kqrl3rv	199	17	remain	remain	VBP
cord-347298-7kqrl3rv	199	18	in	in	IN
cord-347298-7kqrl3rv	199	19	physical	physical	JJ
cord-347298-7kqrl3rv	199	20	contact	contact	NN
cord-347298-7kqrl3rv	199	21	with	with	IN
cord-347298-7kqrl3rv	199	22	the	the	DT
cord-347298-7kqrl3rv	199	23	developing	develop	VBG
cord-347298-7kqrl3rv	199	24	germ	germ	NN
cord-347298-7kqrl3rv	199	25	cells	cell	NNS
cord-347298-7kqrl3rv	199	26	at	at	IN
cord-347298-7kqrl3rv	199	27	all	all	DT
cord-347298-7kqrl3rv	199	28	times	time	NNS
cord-347298-7kqrl3rv	199	29	.	.	.
cord-347298-7kqrl3rv	200	1	During	during	IN
cord-347298-7kqrl3rv	200	2	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	200	3	,	,	,
cord-347298-7kqrl3rv	200	4	a	a	DT
cord-347298-7kqrl3rv	200	5	stem	stem	NN
cord-347298-7kqrl3rv	200	6	cell	cell	NN
cord-347298-7kqrl3rv	200	7	spermatogonium	spermatogonium	NN
cord-347298-7kqrl3rv	200	8	sitting	sit	VBG
cord-347298-7kqrl3rv	200	9	on	on	IN
cord-347298-7kqrl3rv	200	10	the	the	DT
cord-347298-7kqrl3rv	200	11	basement	basement	NN
cord-347298-7kqrl3rv	200	12	membrane	membrane	NN
cord-347298-7kqrl3rv	200	13	of	of	IN
cord-347298-7kqrl3rv	200	14	the	the	DT
cord-347298-7kqrl3rv	200	15	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	200	16	tubule	tubule	NNP
cord-347298-7kqrl3rv	200	17	becomes	become	VBZ
cord-347298-7kqrl3rv	200	18	committed	commit	VBN
cord-347298-7kqrl3rv	200	19	to	to	IN
cord-347298-7kqrl3rv	200	20	a	a	DT
cord-347298-7kqrl3rv	200	21	series	series	NN
cord-347298-7kqrl3rv	200	22	of	of	IN
cord-347298-7kqrl3rv	200	23	mitotic	mitotic	JJ
cord-347298-7kqrl3rv	200	24	divisions	division	NNS
cord-347298-7kqrl3rv	200	25	,	,	,
cord-347298-7kqrl3rv	200	26	producing	produce	VBG
cord-347298-7kqrl3rv	200	27	a	a	DT
cord-347298-7kqrl3rv	200	28	cohort	cohort	NN
cord-347298-7kqrl3rv	200	29	of	of	IN
cord-347298-7kqrl3rv	200	30	spermatocytes	spermatocytes	NNPS
cord-347298-7kqrl3rv	200	31	.	.	.
cord-347298-7kqrl3rv	201	1	The	the	DT
cord-347298-7kqrl3rv	201	2	spermatocytes	spermatocyte	NNS
cord-347298-7kqrl3rv	201	3	subsequently	subsequently	RB
cord-347298-7kqrl3rv	201	4	move	move	VBP
cord-347298-7kqrl3rv	201	5	toward	toward	IN
cord-347298-7kqrl3rv	201	6	the	the	DT
cord-347298-7kqrl3rv	201	7	tubule	tubule	NN
cord-347298-7kqrl3rv	201	8	lumen	lumen	NN
cord-347298-7kqrl3rv	201	9	,	,	,
cord-347298-7kqrl3rv	201	10	passing	pass	VBG
cord-347298-7kqrl3rv	201	11	through	through	IN
cord-347298-7kqrl3rv	201	12	tight	tight	JJ
cord-347298-7kqrl3rv	201	13	junctions	junction	NNS
cord-347298-7kqrl3rv	201	14	between	between	IN
cord-347298-7kqrl3rv	201	15	adjacent	adjacent	JJ
cord-347298-7kqrl3rv	201	16	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	201	17	cells	cell	NNS
cord-347298-7kqrl3rv	201	18	,	,	,
cord-347298-7kqrl3rv	201	19	into	into	IN
cord-347298-7kqrl3rv	201	20	the	the	DT
cord-347298-7kqrl3rv	201	21	highly	highly	RB
cord-347298-7kqrl3rv	201	22	specialized	specialized	JJ
cord-347298-7kqrl3rv	201	23	environment	environment	NN
cord-347298-7kqrl3rv	201	24	of	of	IN
cord-347298-7kqrl3rv	201	25	the	the	DT
cord-347298-7kqrl3rv	201	26	adluminal	adluminal	NNP
cord-347298-7kqrl3rv	201	27	compartment	compartment	NNP
cord-347298-7kqrl3rv	201	28	(	(	-LRB-
cord-347298-7kqrl3rv	201	29	Wang	Wang	NNP
cord-347298-7kqrl3rv	201	30	and	and	CC
cord-347298-7kqrl3rv	201	31	Cheng	Cheng	NNP
cord-347298-7kqrl3rv	201	32	2007	2007	CD
cord-347298-7kqrl3rv	201	33	)	)	-RRB-
cord-347298-7kqrl3rv	201	34	.	.	.
cord-347298-7kqrl3rv	202	1	Within	within	IN
cord-347298-7kqrl3rv	202	2	this	this	DT
cord-347298-7kqrl3rv	202	3	compartment	compartment	NN
cord-347298-7kqrl3rv	202	4	,	,	,
cord-347298-7kqrl3rv	202	5	the	the	DT
cord-347298-7kqrl3rv	202	6	spermatocytes	spermatocytes	NNPS
cord-347298-7kqrl3rv	202	7	divide	divide	VBP
cord-347298-7kqrl3rv	202	8	meiotically	meiotically	RB
cord-347298-7kqrl3rv	202	9	to	to	TO
cord-347298-7kqrl3rv	202	10	produce	produce	VB
cord-347298-7kqrl3rv	202	11	haploid	haploid	JJ
cord-347298-7kqrl3rv	202	12	spermatids	spermatid	NNS
cord-347298-7kqrl3rv	202	13	and	and	CC
cord-347298-7kqrl3rv	202	14	then	then	RB
cord-347298-7kqrl3rv	202	15	undergo	undergo	VB
cord-347298-7kqrl3rv	202	16	differentiation	differentiation	NN
cord-347298-7kqrl3rv	202	17	into	into	IN
cord-347298-7kqrl3rv	202	18	spermatozoa	spermatozoa	NN
cord-347298-7kqrl3rv	202	19	,	,	,
cord-347298-7kqrl3rv	202	20	which	which	WDT
cord-347298-7kqrl3rv	202	21	are	be	VBP
cord-347298-7kqrl3rv	202	22	ultimately	ultimately	RB
cord-347298-7kqrl3rv	202	23	released	release	VBN
cord-347298-7kqrl3rv	202	24	into	into	IN
cord-347298-7kqrl3rv	202	25	the	the	DT
cord-347298-7kqrl3rv	202	26	lumen	lumen	NN
cord-347298-7kqrl3rv	202	27	of	of	IN
cord-347298-7kqrl3rv	202	28	the	the	DT
cord-347298-7kqrl3rv	202	29	tubule	tubule	NN
cord-347298-7kqrl3rv	202	30	leaving	leave	VBG
cord-347298-7kqrl3rv	202	31	behind	behind	IN
cord-347298-7kqrl3rv	202	32	the	the	DT
cord-347298-7kqrl3rv	202	33	majority	majority	NN
cord-347298-7kqrl3rv	202	34	of	of	IN
cord-347298-7kqrl3rv	202	35	their	-PRON-	PRP$
cord-347298-7kqrl3rv	202	36	cytoplasm	cytoplasm	NN
cord-347298-7kqrl3rv	202	37	to	to	TO
cord-347298-7kqrl3rv	202	38	be	be	VB
cord-347298-7kqrl3rv	202	39	digested	digest	VBN
cord-347298-7kqrl3rv	202	40	by	by	IN
cord-347298-7kqrl3rv	202	41	the	the	DT
cord-347298-7kqrl3rv	202	42	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	202	43	cells	cell	NNS
cord-347298-7kqrl3rv	202	44	as	as	IN
cord-347298-7kqrl3rv	202	45	residual	residual	JJ
cord-347298-7kqrl3rv	202	46	bodies	body	NNS
cord-347298-7kqrl3rv	202	47	.	.	.
cord-347298-7kqrl3rv	203	1	The	the	DT
cord-347298-7kqrl3rv	203	2	released	release	VBN
cord-347298-7kqrl3rv	203	3	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	203	4	are	be	VBP
cord-347298-7kqrl3rv	203	5	swept	sweep	VBN
cord-347298-7kqrl3rv	203	6	by	by	IN
cord-347298-7kqrl3rv	203	7	fluid	fluid	NN
cord-347298-7kqrl3rv	203	8	secreted	secrete	VBN
cord-347298-7kqrl3rv	203	9	from	from	IN
cord-347298-7kqrl3rv	203	10	the	the	DT
cord-347298-7kqrl3rv	203	11	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	203	12	cells	cell	NNS
cord-347298-7kqrl3rv	203	13	toward	toward	IN
cord-347298-7kqrl3rv	203	14	the	the	DT
cord-347298-7kqrl3rv	203	15	rete	rete	NNP
cord-347298-7kqrl3rv	203	16	testis	testis	NN
cord-347298-7kqrl3rv	203	17	,	,	,
cord-347298-7kqrl3rv	203	18	a	a	DT
cord-347298-7kqrl3rv	203	19	collecting	collect	VBG
cord-347298-7kqrl3rv	203	20	structure	structure	NN
cord-347298-7kqrl3rv	203	21	lined	line	VBN
cord-347298-7kqrl3rv	203	22	by	by	IN
cord-347298-7kqrl3rv	203	23	a	a	DT
cord-347298-7kqrl3rv	203	24	simple	simple	JJ
cord-347298-7kqrl3rv	203	25	epithelium	epithelium	NN
cord-347298-7kqrl3rv	203	26	that	that	WDT
cord-347298-7kqrl3rv	203	27	is	be	VBZ
cord-347298-7kqrl3rv	203	28	connected	connect	VBN
cord-347298-7kqrl3rv	203	29	to	to	IN
cord-347298-7kqrl3rv	203	30	the	the	DT
cord-347298-7kqrl3rv	203	31	adjacent	adjacent	JJ
cord-347298-7kqrl3rv	203	32	epididymis	epididymis	NN
cord-347298-7kqrl3rv	203	33	by	by	IN
cord-347298-7kqrl3rv	203	34	a	a	DT
cord-347298-7kqrl3rv	203	35	series	series	NN
cord-347298-7kqrl3rv	203	36	of	of	IN
cord-347298-7kqrl3rv	203	37	efferent	efferent	JJ
cord-347298-7kqrl3rv	203	38	ducts	duct	NNS
cord-347298-7kqrl3rv	203	39	.	.	.
cord-347298-7kqrl3rv	204	1	Sperm	sperm	NN
cord-347298-7kqrl3rv	204	2	mature	mature	NN
cord-347298-7kqrl3rv	204	3	and	and	CC
cord-347298-7kqrl3rv	204	4	are	be	VBP
cord-347298-7kqrl3rv	204	5	stored	store	VBN
cord-347298-7kqrl3rv	204	6	in	in	IN
cord-347298-7kqrl3rv	204	7	the	the	DT
cord-347298-7kqrl3rv	204	8	epididymis	epididymis	NN
cord-347298-7kqrl3rv	204	9	,	,	,
cord-347298-7kqrl3rv	204	10	until	until	IN
cord-347298-7kqrl3rv	204	11	they	-PRON-	PRP
cord-347298-7kqrl3rv	204	12	are	be	VBP
cord-347298-7kqrl3rv	204	13	either	either	RB
cord-347298-7kqrl3rv	204	14	released	release	VBN
cord-347298-7kqrl3rv	204	15	through	through	IN
cord-347298-7kqrl3rv	204	16	the	the	DT
cord-347298-7kqrl3rv	204	17	vas	vas	NNP
cord-347298-7kqrl3rv	204	18	deferentia	deferentia	NNP
cord-347298-7kqrl3rv	204	19	at	at	IN
cord-347298-7kqrl3rv	204	20	the	the	DT
cord-347298-7kqrl3rv	204	21	time	time	NN
cord-347298-7kqrl3rv	204	22	of	of	IN
cord-347298-7kqrl3rv	204	23	ejaculation	ejaculation	NN
cord-347298-7kqrl3rv	204	24	or	or	CC
cord-347298-7kqrl3rv	204	25	removed	remove	VBN
cord-347298-7kqrl3rv	204	26	by	by	IN
cord-347298-7kqrl3rv	204	27	epididymal	epididymal	JJ
cord-347298-7kqrl3rv	204	28	phagocytes	phagocyte	NNS
cord-347298-7kqrl3rv	204	29	(	(	-LRB-
cord-347298-7kqrl3rv	204	30	Barratt	Barratt	NNP
cord-347298-7kqrl3rv	204	31	and	and	CC
cord-347298-7kqrl3rv	204	32	Cohen	Cohen	NNP
cord-347298-7kqrl3rv	204	33	1987	1987	CD
cord-347298-7kqrl3rv	204	34	;	;	:
cord-347298-7kqrl3rv	205	1	Roussel	Roussel	NNP
cord-347298-7kqrl3rv	205	2	et	et	NNP
cord-347298-7kqrl3rv	205	3	al	al	NNP
cord-347298-7kqrl3rv	205	4	.	.	.
cord-347298-7kqrl3rv	205	5	1967	1967	CD
cord-347298-7kqrl3rv	205	6	)	)	-RRB-
cord-347298-7kqrl3rv	205	7	.	.	.
cord-347298-7kqrl3rv	206	1	The	the	DT
cord-347298-7kqrl3rv	206	2	process	process	NN
cord-347298-7kqrl3rv	206	3	of	of	IN
cord-347298-7kqrl3rv	206	4	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	206	5	is	be	VBZ
cord-347298-7kqrl3rv	206	6	highly	highly	RB
cord-347298-7kqrl3rv	206	7	organized	organize	VBN
cord-347298-7kqrl3rv	206	8	,	,	,
cord-347298-7kqrl3rv	206	9	with	with	IN
cord-347298-7kqrl3rv	206	10	multiple	multiple	JJ
cord-347298-7kqrl3rv	206	11	generations	generation	NNS
cord-347298-7kqrl3rv	206	12	of	of	IN
cord-347298-7kqrl3rv	206	13	developing	develop	VBG
cord-347298-7kqrl3rv	206	14	germ	germ	NN
cord-347298-7kqrl3rv	206	15	cells	cell	NNS
cord-347298-7kqrl3rv	206	16	in	in	IN
cord-347298-7kqrl3rv	206	17	each	each	DT
cord-347298-7kqrl3rv	206	18	region	region	NN
cord-347298-7kqrl3rv	206	19	of	of	IN
cord-347298-7kqrl3rv	206	20	the	the	DT
cord-347298-7kqrl3rv	206	21	epithelium	epithelium	NN
cord-347298-7kqrl3rv	206	22	maintaining	maintain	VBG
cord-347298-7kqrl3rv	206	23	distinct	distinct	JJ
cord-347298-7kqrl3rv	206	24	,	,	,
cord-347298-7kqrl3rv	206	25	progressing	progress	VBG
cord-347298-7kqrl3rv	206	26	cellular	cellular	JJ
cord-347298-7kqrl3rv	206	27	associations	association	NNS
cord-347298-7kqrl3rv	206	28	or	or	CC
cord-347298-7kqrl3rv	206	29	stages	stage	NNS
cord-347298-7kqrl3rv	206	30	,	,	,
cord-347298-7kqrl3rv	206	31	which	which	WDT
cord-347298-7kqrl3rv	206	32	comprise	comprise	VBP
cord-347298-7kqrl3rv	206	33	the	the	DT
cord-347298-7kqrl3rv	206	34	cycle	cycle	NN
cord-347298-7kqrl3rv	206	35	of	of	IN
cord-347298-7kqrl3rv	206	36	the	the	DT
cord-347298-7kqrl3rv	206	37	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	206	38	epithelium	epithelium	NN
cord-347298-7kqrl3rv	206	39	(	(	-LRB-
cord-347298-7kqrl3rv	206	40	14	14	CD
cord-347298-7kqrl3rv	206	41	stages	stage	NNS
cord-347298-7kqrl3rv	206	42	in	in	IN
cord-347298-7kqrl3rv	206	43	the	the	DT
cord-347298-7kqrl3rv	206	44	rat	rat	NN
cord-347298-7kqrl3rv	206	45	,	,	,
cord-347298-7kqrl3rv	206	46	12	12	CD
cord-347298-7kqrl3rv	206	47	stages	stage	NNS
cord-347298-7kqrl3rv	206	48	in	in	IN
cord-347298-7kqrl3rv	206	49	the	the	DT
cord-347298-7kqrl3rv	206	50	mouse	mouse	NN
cord-347298-7kqrl3rv	206	51	,	,	,
cord-347298-7kqrl3rv	206	52	6	6	CD
cord-347298-7kqrl3rv	206	53	stages	stage	NNS
cord-347298-7kqrl3rv	206	54	in	in	IN
cord-347298-7kqrl3rv	206	55	man	man	NN
cord-347298-7kqrl3rv	206	56	)	)	-RRB-
cord-347298-7kqrl3rv	206	57	.	.	.
cord-347298-7kqrl3rv	207	1	These	these	DT
cord-347298-7kqrl3rv	207	2	stages	stage	NNS
cord-347298-7kqrl3rv	207	3	are	be	VBP
cord-347298-7kqrl3rv	207	4	arranged	arrange	VBN
cord-347298-7kqrl3rv	207	5	in	in	IN
cord-347298-7kqrl3rv	207	6	sequence	sequence	NN
cord-347298-7kqrl3rv	207	7	along	along	IN
cord-347298-7kqrl3rv	207	8	the	the	DT
cord-347298-7kqrl3rv	207	9	length	length	NN
cord-347298-7kqrl3rv	207	10	of	of	IN
cord-347298-7kqrl3rv	207	11	each	each	DT
cord-347298-7kqrl3rv	207	12	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	207	13	tubule	tubule	NN
cord-347298-7kqrl3rv	207	14	,	,	,
cord-347298-7kqrl3rv	207	15	creating	create	VBG
cord-347298-7kqrl3rv	207	16	waves	wave	NNS
cord-347298-7kqrl3rv	207	17	of	of	IN
cord-347298-7kqrl3rv	207	18	coordinated	coordinate	VBN
cord-347298-7kqrl3rv	207	19	spermatogenic	spermatogenic	JJ
cord-347298-7kqrl3rv	207	20	development	development	NN
cord-347298-7kqrl3rv	207	21	(	(	-LRB-
cord-347298-7kqrl3rv	207	22	Clermont	Clermont	NNP
cord-347298-7kqrl3rv	207	23	1972	1972	CD
cord-347298-7kqrl3rv	207	24	)	)	-RRB-
cord-347298-7kqrl3rv	207	25	.	.	.
cord-347298-7kqrl3rv	208	1	Spermatogenesis	Spermatogenesis	NNP
cord-347298-7kqrl3rv	208	2	is	be	VBZ
cord-347298-7kqrl3rv	208	3	maintained	maintain	VBN
cord-347298-7kqrl3rv	208	4	and	and	CC
cord-347298-7kqrl3rv	208	5	controlled	control	VBN
cord-347298-7kqrl3rv	208	6	by	by	IN
cord-347298-7kqrl3rv	208	7	follicle	follicle	NN
cord-347298-7kqrl3rv	208	8	-	-	HYPH
cord-347298-7kqrl3rv	208	9	stimulating	stimulate	VBG
cord-347298-7kqrl3rv	208	10	hormone	hormone	NN
cord-347298-7kqrl3rv	208	11	(	(	-LRB-
cord-347298-7kqrl3rv	208	12	FSH	fsh	NN
cord-347298-7kqrl3rv	208	13	)	)	-RRB-
cord-347298-7kqrl3rv	208	14	and	and	CC
cord-347298-7kqrl3rv	208	15	testosterone	testosterone	NN
cord-347298-7kqrl3rv	208	16	,	,	,
cord-347298-7kqrl3rv	208	17	the	the	DT
cord-347298-7kqrl3rv	208	18	latter	latter	JJ
cord-347298-7kqrl3rv	208	19	being	be	VBG
cord-347298-7kqrl3rv	208	20	produced	produce	VBN
cord-347298-7kqrl3rv	208	21	by	by	IN
cord-347298-7kqrl3rv	208	22	the	the	DT
cord-347298-7kqrl3rv	208	23	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	208	24	cells	cell	NNS
cord-347298-7kqrl3rv	208	25	in	in	IN
cord-347298-7kqrl3rv	208	26	the	the	DT
cord-347298-7kqrl3rv	208	27	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	208	28	tissue	tissue	NN
cord-347298-7kqrl3rv	208	29	under	under	IN
cord-347298-7kqrl3rv	208	30	the	the	DT
cord-347298-7kqrl3rv	208	31	influence	influence	NN
cord-347298-7kqrl3rv	208	32	of	of	IN
cord-347298-7kqrl3rv	208	33	luteinizing	luteinize	VBG
cord-347298-7kqrl3rv	208	34	hormone	hormone	NN
cord-347298-7kqrl3rv	208	35	(	(	-LRB-
cord-347298-7kqrl3rv	208	36	LH	LH	NNP
cord-347298-7kqrl3rv	208	37	)	)	-RRB-
cord-347298-7kqrl3rv	208	38	.	.	.
cord-347298-7kqrl3rv	209	1	Importantly	importantly	RB
cord-347298-7kqrl3rv	209	2	,	,	,
cord-347298-7kqrl3rv	209	3	FSH	fsh	NN
cord-347298-7kqrl3rv	209	4	and	and	CC
cord-347298-7kqrl3rv	209	5	testosterone	testosterone	NN
cord-347298-7kqrl3rv	209	6	act	act	NN
cord-347298-7kqrl3rv	209	7	upon	upon	IN
cord-347298-7kqrl3rv	209	8	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	209	9	cells	cell	NNS
cord-347298-7kqrl3rv	209	10	and	and	CC
cord-347298-7kqrl3rv	209	11	not	not	RB
cord-347298-7kqrl3rv	209	12	directly	directly	RB
cord-347298-7kqrl3rv	209	13	on	on	IN
cord-347298-7kqrl3rv	209	14	the	the	DT
cord-347298-7kqrl3rv	209	15	germ	germ	NN
cord-347298-7kqrl3rv	209	16	cells	cell	NNS
cord-347298-7kqrl3rv	209	17	(	(	-LRB-
cord-347298-7kqrl3rv	209	18	McLachlan	McLachlan	NNP
cord-347298-7kqrl3rv	209	19	et	et	NNP
cord-347298-7kqrl3rv	209	20	al	al	NNP
cord-347298-7kqrl3rv	209	21	.	.	.
cord-347298-7kqrl3rv	209	22	1996	1996	CD
cord-347298-7kqrl3rv	209	23	)	)	-RRB-
cord-347298-7kqrl3rv	209	24	.	.	.
cord-347298-7kqrl3rv	210	1	These	these	DT
cord-347298-7kqrl3rv	210	2	hormones	hormone	NNS
cord-347298-7kqrl3rv	210	3	determine	determine	VBP
cord-347298-7kqrl3rv	210	4	the	the	DT
cord-347298-7kqrl3rv	210	5	efficiency	efficiency	NN
cord-347298-7kqrl3rv	210	6	of	of	IN
cord-347298-7kqrl3rv	210	7	the	the	DT
cord-347298-7kqrl3rv	210	8	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	210	9	process	process	NN
cord-347298-7kqrl3rv	210	10	largely	largely	RB
cord-347298-7kqrl3rv	210	11	by	by	IN
cord-347298-7kqrl3rv	210	12	controlling	control	VBG
cord-347298-7kqrl3rv	210	13	germ	germ	NN
cord-347298-7kqrl3rv	210	14	cell	cell	NN
cord-347298-7kqrl3rv	210	15	survival	survival	NN
cord-347298-7kqrl3rv	210	16	,	,	,
cord-347298-7kqrl3rv	210	17	that	that	RB
cord-347298-7kqrl3rv	210	18	is	is	RB
cord-347298-7kqrl3rv	210	19	,	,	,
cord-347298-7kqrl3rv	210	20	the	the	DT
cord-347298-7kqrl3rv	210	21	balance	balance	NN
cord-347298-7kqrl3rv	210	22	between	between	IN
cord-347298-7kqrl3rv	210	23	differentiation	differentiation	NN
cord-347298-7kqrl3rv	210	24	and	and	CC
cord-347298-7kqrl3rv	210	25	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	210	26	(	(	-LRB-
cord-347298-7kqrl3rv	210	27	Matthiesson	Matthiesson	NNP
cord-347298-7kqrl3rv	210	28	et	et	NNP
cord-347298-7kqrl3rv	210	29	al	al	NNP
cord-347298-7kqrl3rv	210	30	.	.	.
cord-347298-7kqrl3rv	210	31	2006	2006	CD
cord-347298-7kqrl3rv	210	32	;	;	:
cord-347298-7kqrl3rv	210	33	Ruwanpura	Ruwanpura	NNP
cord-347298-7kqrl3rv	210	34	et	et	NNP
cord-347298-7kqrl3rv	210	35	al	al	NNP
cord-347298-7kqrl3rv	210	36	.	.	NNP
cord-347298-7kqrl3rv	210	37	2008	2008	CD
cord-347298-7kqrl3rv	210	38	)	)	-RRB-
cord-347298-7kqrl3rv	210	39	.	.	.
cord-347298-7kqrl3rv	211	1	In	in	IN
cord-347298-7kqrl3rv	211	2	order	order	NN
cord-347298-7kqrl3rv	211	3	to	to	TO
cord-347298-7kqrl3rv	211	4	maintain	maintain	VB
cord-347298-7kqrl3rv	211	5	the	the	DT
cord-347298-7kqrl3rv	211	6	cycle	cycle	NN
cord-347298-7kqrl3rv	211	7	of	of	IN
cord-347298-7kqrl3rv	211	8	the	the	DT
cord-347298-7kqrl3rv	211	9	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	211	10	epithelium	epithelium	NN
cord-347298-7kqrl3rv	211	11	,	,	,
cord-347298-7kqrl3rv	211	12	the	the	DT
cord-347298-7kqrl3rv	211	13	developing	develop	VBG
cord-347298-7kqrl3rv	211	14	germ	germ	NN
cord-347298-7kqrl3rv	211	15	cells	cell	NNS
cord-347298-7kqrl3rv	211	16	and	and	CC
cord-347298-7kqrl3rv	211	17	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	211	18	cells	cell	NNS
cord-347298-7kqrl3rv	211	19	are	be	VBP
cord-347298-7kqrl3rv	211	20	engaged	engage	VBN
cord-347298-7kqrl3rv	211	21	in	in	IN
cord-347298-7kqrl3rv	211	22	continuous	continuous	JJ
cord-347298-7kqrl3rv	211	23	intercellular	intercellular	JJ
cord-347298-7kqrl3rv	211	24	communication	communication	NN
cord-347298-7kqrl3rv	211	25	,	,	,
cord-347298-7kqrl3rv	211	26	although	although	IN
cord-347298-7kqrl3rv	211	27	the	the	DT
cord-347298-7kqrl3rv	211	28	precise	precise	JJ
cord-347298-7kqrl3rv	211	29	nature	nature	NN
cord-347298-7kqrl3rv	211	30	of	of	IN
cord-347298-7kqrl3rv	211	31	this	this	DT
cord-347298-7kqrl3rv	211	32	communication	communication	NN
cord-347298-7kqrl3rv	211	33	remains	remain	VBZ
cord-347298-7kqrl3rv	211	34	very	very	RB
cord-347298-7kqrl3rv	211	35	poorly	poorly	RB
cord-347298-7kqrl3rv	211	36	understood	understand	VBN
cord-347298-7kqrl3rv	211	37	.	.	.
cord-347298-7kqrl3rv	212	1	The	the	DT
cord-347298-7kqrl3rv	212	2	testis	testis	NN
cord-347298-7kqrl3rv	212	3	,	,	,
cord-347298-7kqrl3rv	212	4	and	and	CC
cord-347298-7kqrl3rv	212	5	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	212	6	in	in	IN
cord-347298-7kqrl3rv	212	7	particular	particular	JJ
cord-347298-7kqrl3rv	212	8	,	,	,
cord-347298-7kqrl3rv	212	9	presents	present	VBZ
cord-347298-7kqrl3rv	212	10	a	a	DT
cord-347298-7kqrl3rv	212	11	unique	unique	JJ
cord-347298-7kqrl3rv	212	12	challenge	challenge	NN
cord-347298-7kqrl3rv	212	13	for	for	IN
cord-347298-7kqrl3rv	212	14	the	the	DT
cord-347298-7kqrl3rv	212	15	immune	immune	JJ
cord-347298-7kqrl3rv	212	16	system	system	NN
cord-347298-7kqrl3rv	212	17	.	.	.
cord-347298-7kqrl3rv	213	1	Although	although	IN
cord-347298-7kqrl3rv	213	2	there	there	EX
cord-347298-7kqrl3rv	213	3	are	be	VBP
cord-347298-7kqrl3rv	213	4	reports	report	NNS
cord-347298-7kqrl3rv	213	5	of	of	IN
cord-347298-7kqrl3rv	213	6	direct	direct	JJ
cord-347298-7kqrl3rv	213	7	drainage	drainage	NN
cord-347298-7kqrl3rv	213	8	of	of	IN
cord-347298-7kqrl3rv	213	9	some	some	DT
cord-347298-7kqrl3rv	213	10	lymphatic	lymphatic	JJ
cord-347298-7kqrl3rv	213	11	vessels	vessel	NNS
cord-347298-7kqrl3rv	213	12	to	to	IN
cord-347298-7kqrl3rv	213	13	the	the	DT
cord-347298-7kqrl3rv	213	14	thoracic	thoracic	JJ
cord-347298-7kqrl3rv	213	15	duct	duct	NN
cord-347298-7kqrl3rv	213	16	,	,	,
cord-347298-7kqrl3rv	213	17	there	there	EX
cord-347298-7kqrl3rv	213	18	is	be	VBZ
cord-347298-7kqrl3rv	213	19	no	no	DT
cord-347298-7kqrl3rv	213	20	evidence	evidence	NN
cord-347298-7kqrl3rv	213	21	of	of	IN
cord-347298-7kqrl3rv	213	22	any	any	DT
cord-347298-7kqrl3rv	213	23	structural	structural	JJ
cord-347298-7kqrl3rv	213	24	or	or	CC
cord-347298-7kqrl3rv	213	25	functional	functional	JJ
cord-347298-7kqrl3rv	213	26	deficiency	deficiency	NN
cord-347298-7kqrl3rv	213	27	in	in	IN
cord-347298-7kqrl3rv	213	28	the	the	DT
cord-347298-7kqrl3rv	213	29	efferent	efferent	JJ
cord-347298-7kqrl3rv	213	30	lymphatics	lymphatic	NNS
cord-347298-7kqrl3rv	213	31	of	of	IN
cord-347298-7kqrl3rv	213	32	the	the	DT
cord-347298-7kqrl3rv	213	33	testis	testis	NN
cord-347298-7kqrl3rv	213	34	,	,	,
cord-347298-7kqrl3rv	213	35	and	and	CC
cord-347298-7kqrl3rv	213	36	allogeneic	allogeneic	NN
cord-347298-7kqrl3rv	213	37	cells	cell	NNS
cord-347298-7kqrl3rv	213	38	injected	inject	VBN
cord-347298-7kqrl3rv	213	39	into	into	IN
cord-347298-7kqrl3rv	213	40	the	the	DT
cord-347298-7kqrl3rv	213	41	rat	rat	NN
cord-347298-7kqrl3rv	213	42	testis	testis	NN
cord-347298-7kqrl3rv	213	43	induce	induce	VB
cord-347298-7kqrl3rv	213	44	typical	typical	JJ
cord-347298-7kqrl3rv	213	45	immune	immune	JJ
cord-347298-7kqrl3rv	213	46	responses	response	NNS
cord-347298-7kqrl3rv	213	47	in	in	IN
cord-347298-7kqrl3rv	213	48	the	the	DT
cord-347298-7kqrl3rv	213	49	draining	drain	VBG
cord-347298-7kqrl3rv	213	50	lymph	lymph	NN
cord-347298-7kqrl3rv	213	51	nodes	node	NNS
cord-347298-7kqrl3rv	213	52	(	(	-LRB-
cord-347298-7kqrl3rv	213	53	Fawcett	Fawcett	NNP
cord-347298-7kqrl3rv	213	54	et	et	NNP
cord-347298-7kqrl3rv	213	55	al	al	NNP
cord-347298-7kqrl3rv	213	56	.	.	NNP
cord-347298-7kqrl3rv	213	57	1973	1973	CD
cord-347298-7kqrl3rv	213	58	;	;	:
cord-347298-7kqrl3rv	214	1	Head	Head	NNP
cord-347298-7kqrl3rv	214	2	et	et	NNP
cord-347298-7kqrl3rv	214	3	al	al	NNP
cord-347298-7kqrl3rv	214	4	.	.	.
cord-347298-7kqrl3rv	215	1	1983b	1983b	CD
cord-347298-7kqrl3rv	215	2	;	;	:
cord-347298-7kqrl3rv	215	3	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	215	4	et	et	NNP
cord-347298-7kqrl3rv	215	5	al	al	NNP
cord-347298-7kqrl3rv	215	6	.	.	.
cord-347298-7kqrl3rv	216	1	1998a	1998a	CD
cord-347298-7kqrl3rv	216	2	;	;	:
cord-347298-7kqrl3rv	216	3	Moller	Moller	NNP
cord-347298-7kqrl3rv	216	4	1980	1980	CD
cord-347298-7kqrl3rv	216	5	)	)	-RRB-
cord-347298-7kqrl3rv	216	6	.	.	.
cord-347298-7kqrl3rv	217	1	Nonetheless	nonetheless	RB
cord-347298-7kqrl3rv	217	2	,	,	,
cord-347298-7kqrl3rv	217	3	the	the	DT
cord-347298-7kqrl3rv	217	4	vast	vast	JJ
cord-347298-7kqrl3rv	217	5	majority	majority	NN
cord-347298-7kqrl3rv	217	6	of	of	IN
cord-347298-7kqrl3rv	217	7	spermatogenic	spermatogenic	JJ
cord-347298-7kqrl3rv	217	8	differentiation	differentiation	NN
cord-347298-7kqrl3rv	217	9	occurs	occur	VBZ
cord-347298-7kqrl3rv	217	10	long	long	RB
cord-347298-7kqrl3rv	217	11	after	after	IN
cord-347298-7kqrl3rv	217	12	central	central	JJ
cord-347298-7kqrl3rv	217	13	tolerance	tolerance	NN
cord-347298-7kqrl3rv	217	14	is	be	VBZ
cord-347298-7kqrl3rv	217	15	established	establish	VBN
cord-347298-7kqrl3rv	217	16	and	and	CC
cord-347298-7kqrl3rv	217	17	,	,	,
cord-347298-7kqrl3rv	217	18	while	while	IN
cord-347298-7kqrl3rv	217	19	thymic	thymic	JJ
cord-347298-7kqrl3rv	217	20	expression	expression	NN
cord-347298-7kqrl3rv	217	21	of	of	IN
cord-347298-7kqrl3rv	217	22	some	some	DT
cord-347298-7kqrl3rv	217	23	testicular	testicular	JJ
cord-347298-7kqrl3rv	217	24	antigens	antigen	NNS
cord-347298-7kqrl3rv	217	25	is	be	VBZ
cord-347298-7kqrl3rv	217	26	under	under	IN
cord-347298-7kqrl3rv	217	27	the	the	DT
cord-347298-7kqrl3rv	217	28	control	control	NN
cord-347298-7kqrl3rv	217	29	of	of	IN
cord-347298-7kqrl3rv	217	30	the	the	DT
cord-347298-7kqrl3rv	217	31	Aire	Aire	NNP
cord-347298-7kqrl3rv	217	32	transcription	transcription	NN
cord-347298-7kqrl3rv	217	33	factor	factor	NN
cord-347298-7kqrl3rv	217	34	,	,	,
cord-347298-7kqrl3rv	217	35	it	-PRON-	PRP
cord-347298-7kqrl3rv	217	36	is	be	VBZ
cord-347298-7kqrl3rv	217	37	obvious	obvious	JJ
cord-347298-7kqrl3rv	217	38	from	from	IN
cord-347298-7kqrl3rv	217	39	clinical	clinical	JJ
cord-347298-7kqrl3rv	217	40	and	and	CC
cord-347298-7kqrl3rv	217	41	experimental	experimental	JJ
cord-347298-7kqrl3rv	217	42	studies	study	NNS
cord-347298-7kqrl3rv	217	43	that	that	IN
cord-347298-7kqrl3rv	217	44	germ	germ	NN
cord-347298-7kqrl3rv	217	45	cells	cell	NNS
cord-347298-7kqrl3rv	217	46	express	express	VBP
cord-347298-7kqrl3rv	217	47	multiple	multiple	JJ
cord-347298-7kqrl3rv	217	48	autoreactive	autoreactive	JJ
cord-347298-7kqrl3rv	217	49	antigens	antigen	NNS
cord-347298-7kqrl3rv	217	50	and	and	CC
cord-347298-7kqrl3rv	217	51	are	be	VBP
cord-347298-7kqrl3rv	217	52	highly	highly	RB
cord-347298-7kqrl3rv	217	53	immunogenic	immunogenic	JJ
cord-347298-7kqrl3rv	217	54	when	when	WRB
cord-347298-7kqrl3rv	217	55	brought	bring	VBN
cord-347298-7kqrl3rv	217	56	into	into	IN
cord-347298-7kqrl3rv	217	57	contact	contact	NN
cord-347298-7kqrl3rv	217	58	with	with	IN
cord-347298-7kqrl3rv	217	59	the	the	DT
cord-347298-7kqrl3rv	217	60	immune	immune	JJ
cord-347298-7kqrl3rv	217	61	system	system	NN
cord-347298-7kqrl3rv	217	62	(	(	-LRB-
cord-347298-7kqrl3rv	217	63	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	217	64	et	et	NNP
cord-347298-7kqrl3rv	217	65	al	al	NNP
cord-347298-7kqrl3rv	217	66	.	.	.
cord-347298-7kqrl3rv	217	67	1991	1991	CD
cord-347298-7kqrl3rv	217	68	;	;	:
cord-347298-7kqrl3rv	217	69	Tung	Tung	NNP
cord-347298-7kqrl3rv	217	70	1975	1975	CD
cord-347298-7kqrl3rv	217	71	)	)	-RRB-
cord-347298-7kqrl3rv	217	72	.	.	.
cord-347298-7kqrl3rv	218	1	Surprisingly	surprisingly	RB
cord-347298-7kqrl3rv	218	2	,	,	,
cord-347298-7kqrl3rv	218	3	this	this	DT
cord-347298-7kqrl3rv	218	4	is	be	VBZ
cord-347298-7kqrl3rv	218	5	a	a	DT
cord-347298-7kqrl3rv	218	6	problem	problem	NN
cord-347298-7kqrl3rv	218	7	for	for	IN
cord-347298-7kqrl3rv	218	8	a	a	DT
cord-347298-7kqrl3rv	218	9	relatively	relatively	RB
cord-347298-7kqrl3rv	218	10	small	small	JJ
cord-347298-7kqrl3rv	218	11	cohort	cohort	NN
cord-347298-7kqrl3rv	218	12	of	of	IN
cord-347298-7kqrl3rv	218	13	men	man	NNS
cord-347298-7kqrl3rv	218	14	only	only	RB
cord-347298-7kqrl3rv	218	15	,	,	,
cord-347298-7kqrl3rv	218	16	and	and	CC
cord-347298-7kqrl3rv	218	17	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	218	18	orchitis	orchiti	NNS
cord-347298-7kqrl3rv	218	19	or	or	CC
cord-347298-7kqrl3rv	218	20	epididymitis	epididymitis	NN
cord-347298-7kqrl3rv	218	21	is	be	VBZ
cord-347298-7kqrl3rv	218	22	rarely	rarely	RB
cord-347298-7kqrl3rv	218	23	reported	report	VBN
cord-347298-7kqrl3rv	218	24	in	in	IN
cord-347298-7kqrl3rv	218	25	humans	human	NNS
cord-347298-7kqrl3rv	218	26	,	,	,
cord-347298-7kqrl3rv	218	27	except	except	IN
cord-347298-7kqrl3rv	218	28	in	in	IN
cord-347298-7kqrl3rv	218	29	the	the	DT
cord-347298-7kqrl3rv	218	30	context	context	NN
cord-347298-7kqrl3rv	218	31	of	of	IN
cord-347298-7kqrl3rv	218	32	local	local	JJ
cord-347298-7kqrl3rv	218	33	infection	infection	NN
cord-347298-7kqrl3rv	218	34	(	(	-LRB-
cord-347298-7kqrl3rv	218	35	Krieger	Krieger	NNP
cord-347298-7kqrl3rv	218	36	1984	1984	CD
cord-347298-7kqrl3rv	218	37	)	)	-RRB-
cord-347298-7kqrl3rv	218	38	.	.	.
cord-347298-7kqrl3rv	219	1	Even	even	RB
cord-347298-7kqrl3rv	219	2	allowing	allow	VBG
cord-347298-7kqrl3rv	219	3	for	for	IN
cord-347298-7kqrl3rv	219	4	the	the	DT
cord-347298-7kqrl3rv	219	5	possibility	possibility	NN
cord-347298-7kqrl3rv	219	6	that	that	IN
cord-347298-7kqrl3rv	219	7	most	most	JJS
cord-347298-7kqrl3rv	219	8	cases	case	NNS
cord-347298-7kqrl3rv	219	9	of	of	IN
cord-347298-7kqrl3rv	219	10	spontaneous	spontaneous	JJ
cord-347298-7kqrl3rv	219	11	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	219	12	reactions	reaction	NNS
cord-347298-7kqrl3rv	219	13	against	against	IN
cord-347298-7kqrl3rv	219	14	the	the	DT
cord-347298-7kqrl3rv	219	15	developing	develop	VBG
cord-347298-7kqrl3rv	219	16	germ	germ	NN
cord-347298-7kqrl3rv	219	17	cells	cell	NNS
cord-347298-7kqrl3rv	219	18	are	be	VBP
cord-347298-7kqrl3rv	219	19	never	never	RB
cord-347298-7kqrl3rv	219	20	diagnosed	diagnose	VBN
cord-347298-7kqrl3rv	219	21	,	,	,
cord-347298-7kqrl3rv	219	22	since	since	IN
cord-347298-7kqrl3rv	219	23	they	-PRON-	PRP
cord-347298-7kqrl3rv	219	24	would	would	MD
cord-347298-7kqrl3rv	219	25	occur	occur	VB
cord-347298-7kqrl3rv	219	26	early	early	RB
cord-347298-7kqrl3rv	219	27	in	in	IN
cord-347298-7kqrl3rv	219	28	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	219	29	life	life	NN
cord-347298-7kqrl3rv	219	30	,	,	,
cord-347298-7kqrl3rv	219	31	and	and	CC
cord-347298-7kqrl3rv	219	32	would	would	MD
cord-347298-7kqrl3rv	219	33	simply	simply	RB
cord-347298-7kqrl3rv	219	34	present	present	VB
cord-347298-7kqrl3rv	219	35	as	as	IN
cord-347298-7kqrl3rv	219	36	spermatogenic	spermatogenic	JJ
cord-347298-7kqrl3rv	219	37	failure	failure	NN
cord-347298-7kqrl3rv	219	38	during	during	IN
cord-347298-7kqrl3rv	219	39	infertility	infertility	NN
cord-347298-7kqrl3rv	219	40	work	work	NN
cord-347298-7kqrl3rv	219	41	-	-	HYPH
cord-347298-7kqrl3rv	219	42	ups	up	NNS
cord-347298-7kqrl3rv	219	43	(	(	-LRB-
cord-347298-7kqrl3rv	219	44	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	219	45	and	and	CC
cord-347298-7kqrl3rv	219	46	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	219	47	2005	2005	CD
cord-347298-7kqrl3rv	219	48	;	;	:
cord-347298-7kqrl3rv	219	49	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	219	50	et	et	NNP
cord-347298-7kqrl3rv	219	51	al	al	NNP
cord-347298-7kqrl3rv	219	52	.	.	NNP
cord-347298-7kqrl3rv	219	53	2008	2008	CD
cord-347298-7kqrl3rv	219	54	)	)	-RRB-
cord-347298-7kqrl3rv	220	1	,	,	,
cord-347298-7kqrl3rv	220	2	why	why	WRB
cord-347298-7kqrl3rv	220	3	are	be	VBP
cord-347298-7kqrl3rv	220	4	such	such	JJ
cord-347298-7kqrl3rv	220	5	reactions	reaction	NNS
cord-347298-7kqrl3rv	220	6	not	not	RB
cord-347298-7kqrl3rv	220	7	more	more	RBR
cord-347298-7kqrl3rv	220	8	common	common	JJ
cord-347298-7kqrl3rv	220	9	?	?	.
cord-347298-7kqrl3rv	221	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	221	2	is	be	VBZ
cord-347298-7kqrl3rv	221	3	widely	widely	RB
cord-347298-7kqrl3rv	221	4	believed	believe	VBN
cord-347298-7kqrl3rv	221	5	that	that	IN
cord-347298-7kqrl3rv	221	6	the	the	DT
cord-347298-7kqrl3rv	221	7	blood	blood	NN
cord-347298-7kqrl3rv	221	8	-	-	HYPH
cord-347298-7kqrl3rv	221	9	testis	testis	NN
cord-347298-7kqrl3rv	221	10	barrier	barrier	NN
cord-347298-7kqrl3rv	221	11	plays	play	VBZ
cord-347298-7kqrl3rv	221	12	a	a	DT
cord-347298-7kqrl3rv	221	13	role	role	NN
cord-347298-7kqrl3rv	221	14	in	in	IN
cord-347298-7kqrl3rv	221	15	protecting	protect	VBG
cord-347298-7kqrl3rv	221	16	testicular	testicular	JJ
cord-347298-7kqrl3rv	221	17	antigens	antigen	NNS
cord-347298-7kqrl3rv	221	18	from	from	IN
cord-347298-7kqrl3rv	221	19	the	the	DT
cord-347298-7kqrl3rv	221	20	immune	immune	JJ
cord-347298-7kqrl3rv	221	21	system	system	NN
cord-347298-7kqrl3rv	221	22	.	.	.
cord-347298-7kqrl3rv	222	1	However	however	RB
cord-347298-7kqrl3rv	222	2	,	,	,
cord-347298-7kqrl3rv	222	3	as	as	IN
cord-347298-7kqrl3rv	222	4	a	a	DT
cord-347298-7kqrl3rv	222	5	result	result	NN
cord-347298-7kqrl3rv	222	6	of	of	IN
cord-347298-7kqrl3rv	222	7	a	a	DT
cord-347298-7kqrl3rv	222	8	common	common	JJ
cord-347298-7kqrl3rv	222	9	misunderstanding	misunderstanding	NN
cord-347298-7kqrl3rv	222	10	of	of	IN
cord-347298-7kqrl3rv	222	11	the	the	DT
cord-347298-7kqrl3rv	222	12	nature	nature	NN
cord-347298-7kqrl3rv	222	13	of	of	IN
cord-347298-7kqrl3rv	222	14	this	this	DT
cord-347298-7kqrl3rv	222	15	vitally	vitally	RB
cord-347298-7kqrl3rv	222	16	important	important	JJ
cord-347298-7kqrl3rv	222	17	structure	structure	NN
cord-347298-7kqrl3rv	222	18	,	,	,
cord-347298-7kqrl3rv	222	19	its	-PRON-	PRP$
cord-347298-7kqrl3rv	222	20	actual	actual	JJ
cord-347298-7kqrl3rv	222	21	role	role	NN
cord-347298-7kqrl3rv	222	22	is	be	VBZ
cord-347298-7kqrl3rv	222	23	usually	usually	RB
cord-347298-7kqrl3rv	222	24	overestimated	overestimate	VBN
cord-347298-7kqrl3rv	222	25	.	.	.
cord-347298-7kqrl3rv	223	1	Critically	critically	RB
cord-347298-7kqrl3rv	223	2	,	,	,
cord-347298-7kqrl3rv	223	3	the	the	DT
cord-347298-7kqrl3rv	223	4	blood	blood	NN
cord-347298-7kqrl3rv	223	5	-	-	HYPH
cord-347298-7kqrl3rv	223	6	testis	testis	NN
cord-347298-7kqrl3rv	223	7	barrier	barrier	NN
cord-347298-7kqrl3rv	223	8	involves	involve	VBZ
cord-347298-7kqrl3rv	223	9	highly	highly	RB
cord-347298-7kqrl3rv	223	10	specialized	specialized	JJ
cord-347298-7kqrl3rv	223	11	occluding	occlude	VBG
cord-347298-7kqrl3rv	223	12	or	or	CC
cord-347298-7kqrl3rv	223	13	tight	tight	JJ
cord-347298-7kqrl3rv	223	14	junctions	junction	NNS
cord-347298-7kqrl3rv	223	15	between	between	IN
cord-347298-7kqrl3rv	223	16	adjacent	adjacent	JJ
cord-347298-7kqrl3rv	223	17	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	223	18	cells	cell	NNS
cord-347298-7kqrl3rv	223	19	,	,	,
cord-347298-7kqrl3rv	223	20	which	which	WDT
cord-347298-7kqrl3rv	223	21	separate	separate	VBP
cord-347298-7kqrl3rv	223	22	the	the	DT
cord-347298-7kqrl3rv	223	23	spermatogonial	spermatogonial	JJ
cord-347298-7kqrl3rv	223	24	and	and	CC
cord-347298-7kqrl3rv	223	25	early	early	JJ
cord-347298-7kqrl3rv	223	26	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	223	27	cells	cell	NNS
cord-347298-7kqrl3rv	223	28	from	from	IN
cord-347298-7kqrl3rv	223	29	the	the	DT
cord-347298-7kqrl3rv	223	30	majority	majority	NN
cord-347298-7kqrl3rv	223	31	of	of	IN
cord-347298-7kqrl3rv	223	32	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	223	33	and	and	CC
cord-347298-7kqrl3rv	223	34	postmeiotic	postmeiotic	JJ
cord-347298-7kqrl3rv	223	35	germ	germ	NN
cord-347298-7kqrl3rv	223	36	cells	cell	NNS
cord-347298-7kqrl3rv	223	37	(	(	-LRB-
cord-347298-7kqrl3rv	223	38	Dym	Dym	NNP
cord-347298-7kqrl3rv	223	39	and	and	CC
cord-347298-7kqrl3rv	223	40	Fawcett	Fawcett	NNP
cord-347298-7kqrl3rv	223	41	1970	1970	CD
cord-347298-7kqrl3rv	223	42	;	;	:
cord-347298-7kqrl3rv	223	43	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	223	44	et	et	FW
cord-347298-7kqrl3rv	223	45	al	al	NNP
cord-347298-7kqrl3rv	223	46	.	.	NNP
cord-347298-7kqrl3rv	223	47	1969	1969	CD
cord-347298-7kqrl3rv	223	48	)	)	-RRB-
cord-347298-7kqrl3rv	223	49	.	.	.
cord-347298-7kqrl3rv	224	1	The	the	DT
cord-347298-7kqrl3rv	224	2	structure	structure	NN
cord-347298-7kqrl3rv	224	3	and	and	CC
cord-347298-7kqrl3rv	224	4	functions	function	NNS
cord-347298-7kqrl3rv	224	5	of	of	IN
cord-347298-7kqrl3rv	224	6	the	the	DT
cord-347298-7kqrl3rv	224	7	barrier	barrier	NN
cord-347298-7kqrl3rv	224	8	do	do	VBP
cord-347298-7kqrl3rv	224	9	not	not	RB
cord-347298-7kqrl3rv	224	10	need	need	VB
cord-347298-7kqrl3rv	224	11	to	to	TO
cord-347298-7kqrl3rv	224	12	be	be	VB
cord-347298-7kqrl3rv	224	13	discussed	discuss	VBN
cord-347298-7kqrl3rv	224	14	in	in	IN
cord-347298-7kqrl3rv	224	15	detail	detail	NN
cord-347298-7kqrl3rv	224	16	here	here	RB
cord-347298-7kqrl3rv	224	17	,	,	,
cord-347298-7kqrl3rv	224	18	as	as	IN
cord-347298-7kqrl3rv	224	19	this	this	DT
cord-347298-7kqrl3rv	224	20	topic	topic	NN
cord-347298-7kqrl3rv	224	21	is	be	VBZ
cord-347298-7kqrl3rv	224	22	covered	cover	VBN
cord-347298-7kqrl3rv	224	23	in	in	IN
cord-347298-7kqrl3rv	224	24	much	much	RB
cord-347298-7kqrl3rv	224	25	more	more	JJR
cord-347298-7kqrl3rv	224	26	detail	detail	NN
cord-347298-7kqrl3rv	224	27	in	in	IN
cord-347298-7kqrl3rv	224	28	other	other	JJ
cord-347298-7kqrl3rv	224	29	chapters	chapter	NNS
cord-347298-7kqrl3rv	224	30	in	in	IN
cord-347298-7kqrl3rv	224	31	this	this	DT
cord-347298-7kqrl3rv	224	32	volume	volume	NN
cord-347298-7kqrl3rv	224	33	(	(	-LRB-
cord-347298-7kqrl3rv	224	34	see	see	VB
cord-347298-7kqrl3rv	224	35	Chapter	Chapter	NNP
cord-347298-7kqrl3rv	224	36	11.05	11.05	CD
cord-347298-7kqrl3rv	224	37	)	)	-RRB-
cord-347298-7kqrl3rv	224	38	.	.	.
cord-347298-7kqrl3rv	225	1	By	by	IN
cord-347298-7kqrl3rv	225	2	preventing	prevent	VBG
cord-347298-7kqrl3rv	225	3	the	the	DT
cord-347298-7kqrl3rv	225	4	passage	passage	NN
cord-347298-7kqrl3rv	225	5	of	of	IN
cord-347298-7kqrl3rv	225	6	most	most	JJS
cord-347298-7kqrl3rv	225	7	molecules	molecule	NNS
cord-347298-7kqrl3rv	225	8	between	between	IN
cord-347298-7kqrl3rv	225	9	adjacent	adjacent	JJ
cord-347298-7kqrl3rv	225	10	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	225	11	cells	cell	NNS
cord-347298-7kqrl3rv	225	12	,	,	,
cord-347298-7kqrl3rv	225	13	the	the	DT
cord-347298-7kqrl3rv	225	14	bloodtestis	bloodtestis	NNP
cord-347298-7kqrl3rv	225	15	barrier	barrier	NN
cord-347298-7kqrl3rv	225	16	allows	allow	VBZ
cord-347298-7kqrl3rv	225	17	the	the	DT
cord-347298-7kqrl3rv	225	18	creation	creation	NN
cord-347298-7kqrl3rv	225	19	of	of	IN
cord-347298-7kqrl3rv	225	20	a	a	DT
cord-347298-7kqrl3rv	225	21	highly	highly	RB
cord-347298-7kqrl3rv	225	22	specialized	specialized	JJ
cord-347298-7kqrl3rv	225	23	biochemical	biochemical	JJ
cord-347298-7kqrl3rv	225	24	environment	environment	NN
cord-347298-7kqrl3rv	225	25	essential	essential	JJ
cord-347298-7kqrl3rv	225	26	for	for	IN
cord-347298-7kqrl3rv	225	27	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	225	28	development	development	NN
cord-347298-7kqrl3rv	225	29	(	(	-LRB-
cord-347298-7kqrl3rv	225	30	Cheng	Cheng	NNP
cord-347298-7kqrl3rv	225	31	and	and	CC
cord-347298-7kqrl3rv	225	32	Mruk	Mruk	NNP
cord-347298-7kqrl3rv	225	33	2002	2002	CD
cord-347298-7kqrl3rv	225	34	;	;	:
cord-347298-7kqrl3rv	225	35	Griswold	Griswold	NNP
cord-347298-7kqrl3rv	225	36	1988	1988	CD
cord-347298-7kqrl3rv	225	37	)	)	-RRB-
cord-347298-7kqrl3rv	225	38	.	.	.
cord-347298-7kqrl3rv	226	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	226	2	also	also	RB
cord-347298-7kqrl3rv	226	3	blocks	block	VBZ
cord-347298-7kqrl3rv	226	4	access	access	NN
cord-347298-7kqrl3rv	226	5	by	by	IN
cord-347298-7kqrl3rv	226	6	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	226	7	,	,	,
cord-347298-7kqrl3rv	226	8	complement	complement	NN
cord-347298-7kqrl3rv	226	9	,	,	,
cord-347298-7kqrl3rv	226	10	and	and	CC
cord-347298-7kqrl3rv	226	11	antibody	antibody	NN
cord-347298-7kqrl3rv	226	12	(	(	-LRB-
cord-347298-7kqrl3rv	226	13	Ben	Ben	NNP
cord-347298-7kqrl3rv	226	14	et	et	NNP
cord-347298-7kqrl3rv	226	15	al	al	NNP
cord-347298-7kqrl3rv	226	16	.	.	.
cord-347298-7kqrl3rv	226	17	1986	1986	CD
cord-347298-7kqrl3rv	226	18	;	;	:
cord-347298-7kqrl3rv	226	19	Yule	Yule	NNP
cord-347298-7kqrl3rv	226	20	et	et	NNP
cord-347298-7kqrl3rv	226	21	al	al	NNP
cord-347298-7kqrl3rv	226	22	.	.	.
cord-347298-7kqrl3rv	226	23	1988	1988	CD
cord-347298-7kqrl3rv	226	24	)	)	-RRB-
cord-347298-7kqrl3rv	226	25	.	.	.
cord-347298-7kqrl3rv	227	1	By	by	IN
cord-347298-7kqrl3rv	227	2	contrast	contrast	NN
cord-347298-7kqrl3rv	227	3	,	,	,
cord-347298-7kqrl3rv	227	4	the	the	DT
cord-347298-7kqrl3rv	227	5	vascular	vascular	JJ
cord-347298-7kqrl3rv	227	6	endothelium	endothelium	NN
cord-347298-7kqrl3rv	227	7	and	and	CC
cord-347298-7kqrl3rv	227	8	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	227	9	cells	cell	NNS
cord-347298-7kqrl3rv	227	10	surrounding	surround	VBG
cord-347298-7kqrl3rv	227	11	the	the	DT
cord-347298-7kqrl3rv	227	12	tubules	tubule	NNS
cord-347298-7kqrl3rv	227	13	play	play	VB
cord-347298-7kqrl3rv	227	14	a	a	DT
cord-347298-7kqrl3rv	227	15	negligible	negligible	JJ
cord-347298-7kqrl3rv	227	16	role	role	NN
cord-347298-7kqrl3rv	227	17	in	in	IN
cord-347298-7kqrl3rv	227	18	maintaining	maintain	VBG
cord-347298-7kqrl3rv	227	19	the	the	DT
cord-347298-7kqrl3rv	227	20	blood	blood	NN
cord-347298-7kqrl3rv	227	21	-	-	HYPH
cord-347298-7kqrl3rv	227	22	testis	testis	NN
cord-347298-7kqrl3rv	227	23	barrier	barrier	NN
cord-347298-7kqrl3rv	227	24	in	in	IN
cord-347298-7kqrl3rv	227	25	practical	practical	JJ
cord-347298-7kqrl3rv	227	26	terms	term	NNS
cord-347298-7kqrl3rv	227	27	,	,	,
cord-347298-7kqrl3rv	227	28	and	and	CC
cord-347298-7kqrl3rv	227	29	immune	immune	JJ
cord-347298-7kqrl3rv	227	30	cells	cell	NNS
cord-347298-7kqrl3rv	227	31	and	and	CC
cord-347298-7kqrl3rv	227	32	proteins	protein	NNS
cord-347298-7kqrl3rv	227	33	have	have	VBP
cord-347298-7kqrl3rv	227	34	relatively	relatively	RB
cord-347298-7kqrl3rv	227	35	free	free	JJ
cord-347298-7kqrl3rv	227	36	access	access	NN
cord-347298-7kqrl3rv	227	37	to	to	IN
cord-347298-7kqrl3rv	227	38	the	the	DT
cord-347298-7kqrl3rv	227	39	interstitium	interstitium	NN
cord-347298-7kqrl3rv	227	40	and	and	CC
cord-347298-7kqrl3rv	227	41	basal	basal	JJ
cord-347298-7kqrl3rv	227	42	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	227	43	epithelium	epithelium	NN
cord-347298-7kqrl3rv	227	44	(	(	-LRB-
cord-347298-7kqrl3rv	227	45	Mahi	Mahi	NNP
cord-347298-7kqrl3rv	227	46	-	-	HYPH
cord-347298-7kqrl3rv	227	47	Brown	Brown	NNP
cord-347298-7kqrl3rv	227	48	et	et	NNP
cord-347298-7kqrl3rv	227	49	al	al	NNP
cord-347298-7kqrl3rv	227	50	.	.	.
cord-347298-7kqrl3rv	228	1	1988	1988	CD
cord-347298-7kqrl3rv	228	2	;	;	:
cord-347298-7kqrl3rv	228	3	Yule	Yule	NNP
cord-347298-7kqrl3rv	228	4	et	et	NNP
cord-347298-7kqrl3rv	228	5	al	al	NNP
cord-347298-7kqrl3rv	228	6	.	.	.
cord-347298-7kqrl3rv	228	7	1988	1988	CD
cord-347298-7kqrl3rv	228	8	)	)	-RRB-
cord-347298-7kqrl3rv	228	9	.	.	.
cord-347298-7kqrl3rv	229	1	Thus	thus	RB
cord-347298-7kqrl3rv	229	2	,	,	,
cord-347298-7kqrl3rv	229	3	this	this	DT
cord-347298-7kqrl3rv	229	4	barrier	barrier	NN
cord-347298-7kqrl3rv	229	5	is	be	VBZ
cord-347298-7kqrl3rv	229	6	quite	quite	RB
cord-347298-7kqrl3rv	229	7	different	different	JJ
cord-347298-7kqrl3rv	229	8	in	in	IN
cord-347298-7kqrl3rv	229	9	properties	property	NNS
cord-347298-7kqrl3rv	229	10	and	and	CC
cord-347298-7kqrl3rv	229	11	function	function	VB
cord-347298-7kqrl3rv	229	12	from	from	IN
cord-347298-7kqrl3rv	229	13	the	the	DT
cord-347298-7kqrl3rv	229	14	blood	blood	NN
cord-347298-7kqrl3rv	229	15	-	-	HYPH
cord-347298-7kqrl3rv	229	16	brain	brain	NN
cord-347298-7kqrl3rv	229	17	barrier	barrier	NN
cord-347298-7kqrl3rv	229	18	,	,	,
cord-347298-7kqrl3rv	229	19	located	locate	VBN
cord-347298-7kqrl3rv	229	20	on	on	IN
cord-347298-7kqrl3rv	229	21	the	the	DT
cord-347298-7kqrl3rv	229	22	vascular	vascular	JJ
cord-347298-7kqrl3rv	229	23	endothelium	endothelium	NN
cord-347298-7kqrl3rv	229	24	,	,	,
cord-347298-7kqrl3rv	229	25	or	or	CC
cord-347298-7kqrl3rv	229	26	the	the	DT
cord-347298-7kqrl3rv	229	27	trophoblastic	trophoblastic	JJ
cord-347298-7kqrl3rv	229	28	barrier	barrier	NN
cord-347298-7kqrl3rv	229	29	of	of	IN
cord-347298-7kqrl3rv	229	30	pregnancy	pregnancy	NN
cord-347298-7kqrl3rv	229	31	,	,	,
cord-347298-7kqrl3rv	229	32	which	which	WDT
cord-347298-7kqrl3rv	229	33	entirely	entirely	RB
cord-347298-7kqrl3rv	229	34	segregates	segregate	VBZ
cord-347298-7kqrl3rv	229	35	the	the	DT
cord-347298-7kqrl3rv	229	36	developing	develop	VBG
cord-347298-7kqrl3rv	229	37	fetal	fetal	JJ
cord-347298-7kqrl3rv	229	38	tissues	tissue	NNS
cord-347298-7kqrl3rv	229	39	from	from	IN
cord-347298-7kqrl3rv	229	40	the	the	DT
cord-347298-7kqrl3rv	229	41	maternal	maternal	JJ
cord-347298-7kqrl3rv	229	42	host	host	NN
cord-347298-7kqrl3rv	229	43	.	.	.
cord-347298-7kqrl3rv	230	1	A	a	DT
cord-347298-7kqrl3rv	230	2	reinterpretation	reinterpretation	NN
cord-347298-7kqrl3rv	230	3	of	of	IN
cord-347298-7kqrl3rv	230	4	the	the	DT
cord-347298-7kqrl3rv	230	5	blood	blood	NN
cord-347298-7kqrl3rv	230	6	-	-	HYPH
cord-347298-7kqrl3rv	230	7	testis	testis	NN
cord-347298-7kqrl3rv	230	8	barrier	barrier	NN
cord-347298-7kqrl3rv	230	9	as	as	IN
cord-347298-7kqrl3rv	230	10	a	a	DT
cord-347298-7kqrl3rv	230	11	series	series	NN
cord-347298-7kqrl3rv	230	12	of	of	IN
cord-347298-7kqrl3rv	230	13	cellular	cellular	JJ
cord-347298-7kqrl3rv	230	14	elements	element	NNS
cord-347298-7kqrl3rv	230	15	that	that	WDT
cord-347298-7kqrl3rv	230	16	protects	protect	VBZ
cord-347298-7kqrl3rv	230	17	the	the	DT
cord-347298-7kqrl3rv	230	18	germ	germ	NN
cord-347298-7kqrl3rv	230	19	cells	cell	NNS
cord-347298-7kqrl3rv	230	20	from	from	IN
cord-347298-7kqrl3rv	230	21	harmful	harmful	JJ
cord-347298-7kqrl3rv	230	22	influences	influence	NNS
cord-347298-7kqrl3rv	230	23	has	have	VBZ
cord-347298-7kqrl3rv	230	24	been	be	VBN
cord-347298-7kqrl3rv	230	25	proposed	propose	VBN
cord-347298-7kqrl3rv	230	26	more	more	RBR
cord-347298-7kqrl3rv	230	27	recently	recently	RB
cord-347298-7kqrl3rv	231	1	(	(	-LRB-
cord-347298-7kqrl3rv	231	2	Bart	Bart	NNP
cord-347298-7kqrl3rv	231	3	et	et	NNP
cord-347298-7kqrl3rv	231	4	al	al	NNP
cord-347298-7kqrl3rv	231	5	.	.	.
cord-347298-7kqrl3rv	231	6	2002	2002	CD
cord-347298-7kqrl3rv	231	7	)	)	-RRB-
cord-347298-7kqrl3rv	231	8	.	.	.
cord-347298-7kqrl3rv	232	1	In	in	IN
cord-347298-7kqrl3rv	232	2	this	this	DT
cord-347298-7kqrl3rv	232	3	model	model	NN
cord-347298-7kqrl3rv	232	4	,	,	,
cord-347298-7kqrl3rv	232	5	the	the	DT
cord-347298-7kqrl3rv	232	6	bloodtestis	bloodtestis	NNP
cord-347298-7kqrl3rv	232	7	barrier	barrier	NN
cord-347298-7kqrl3rv	232	8	consists	consist	VBZ
cord-347298-7kqrl3rv	232	9	not	not	RB
cord-347298-7kqrl3rv	232	10	only	only	RB
cord-347298-7kqrl3rv	232	11	of	of	IN
cord-347298-7kqrl3rv	232	12	the	the	DT
cord-347298-7kqrl3rv	232	13	structural	structural	JJ
cord-347298-7kqrl3rv	232	14	elements	element	NNS
cord-347298-7kqrl3rv	232	15	already	already	RB
cord-347298-7kqrl3rv	232	16	discussed	discuss	VBN
cord-347298-7kqrl3rv	232	17	,	,	,
cord-347298-7kqrl3rv	232	18	but	but	CC
cord-347298-7kqrl3rv	232	19	also	also	RB
cord-347298-7kqrl3rv	232	20	the	the	DT
cord-347298-7kqrl3rv	232	21	efflux	efflux	NN
cord-347298-7kqrl3rv	232	22	pump	pump	NN
cord-347298-7kqrl3rv	232	23	barrier	barrier	NN
cord-347298-7kqrl3rv	232	24	system	system	NN
cord-347298-7kqrl3rv	232	25	involving	involve	VBG
cord-347298-7kqrl3rv	232	26	the	the	DT
cord-347298-7kqrl3rv	232	27	drug	drug	NN
cord-347298-7kqrl3rv	232	28	transport	transport	NN
cord-347298-7kqrl3rv	232	29	proteins	protein	NNS
cord-347298-7kqrl3rv	232	30	p	p	NN
cord-347298-7kqrl3rv	232	31	-	-	HYPH
cord-347298-7kqrl3rv	232	32	glycoprotein	glycoprotein	NN
cord-347298-7kqrl3rv	232	33	and	and	CC
cord-347298-7kqrl3rv	232	34	the	the	DT
cord-347298-7kqrl3rv	232	35	multidrug	multidrug	NN
cord-347298-7kqrl3rv	232	36	resistance	resistance	NN
cord-347298-7kqrl3rv	232	37	-	-	HYPH
cord-347298-7kqrl3rv	232	38	associated	associate	VBN
cord-347298-7kqrl3rv	232	39	protein-1	protein-1	NNP
cord-347298-7kqrl3rv	232	40	expressed	express	VBD
cord-347298-7kqrl3rv	232	41	on	on	IN
cord-347298-7kqrl3rv	232	42	the	the	DT
cord-347298-7kqrl3rv	232	43	capillary	capillary	JJ
cord-347298-7kqrl3rv	232	44	endothelium	endothelium	NN
cord-347298-7kqrl3rv	232	45	,	,	,
cord-347298-7kqrl3rv	232	46	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	232	47	myoid	myoid	NNP
cord-347298-7kqrl3rv	232	48	cells	cell	NNS
cord-347298-7kqrl3rv	232	49	,	,	,
cord-347298-7kqrl3rv	232	50	and	and	CC
cord-347298-7kqrl3rv	232	51	the	the	DT
cord-347298-7kqrl3rv	232	52	basal	basal	NN
cord-347298-7kqrl3rv	232	53	aspect	aspect	NN
cord-347298-7kqrl3rv	232	54	of	of	IN
cord-347298-7kqrl3rv	232	55	the	the	DT
cord-347298-7kqrl3rv	232	56	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	232	57	cells	cell	NNS
cord-347298-7kqrl3rv	233	1	(	(	-LRB-
cord-347298-7kqrl3rv	233	2	Bart	Bart	NNP
cord-347298-7kqrl3rv	233	3	et	et	NNP
cord-347298-7kqrl3rv	233	4	al	al	NNP
cord-347298-7kqrl3rv	233	5	.	.	.
cord-347298-7kqrl3rv	234	1	2004	2004	CD
cord-347298-7kqrl3rv	234	2	;	;	:
cord-347298-7kqrl3rv	234	3	Melaine	Melaine	NNP
cord-347298-7kqrl3rv	234	4	et	et	NNP
cord-347298-7kqrl3rv	234	5	al	al	NNP
cord-347298-7kqrl3rv	234	6	.	.	.
cord-347298-7kqrl3rv	234	7	2002	2002	CD
cord-347298-7kqrl3rv	234	8	)	)	-RRB-
cord-347298-7kqrl3rv	234	9	.	.	.
cord-347298-7kqrl3rv	235	1	While	while	IN
cord-347298-7kqrl3rv	235	2	these	these	DT
cord-347298-7kqrl3rv	235	3	elements	element	NNS
cord-347298-7kqrl3rv	235	4	may	may	MD
cord-347298-7kqrl3rv	235	5	certainly	certainly	RB
cord-347298-7kqrl3rv	235	6	be	be	VB
cord-347298-7kqrl3rv	235	7	important	important	JJ
cord-347298-7kqrl3rv	235	8	for	for	IN
cord-347298-7kqrl3rv	235	9	protection	protection	NN
cord-347298-7kqrl3rv	235	10	of	of	IN
cord-347298-7kqrl3rv	235	11	the	the	DT
cord-347298-7kqrl3rv	235	12	testis	testis	NN
cord-347298-7kqrl3rv	235	13	against	against	IN
cord-347298-7kqrl3rv	235	14	toxic	toxic	JJ
cord-347298-7kqrl3rv	235	15	agents	agent	NNS
cord-347298-7kqrl3rv	235	16	,	,	,
cord-347298-7kqrl3rv	235	17	their	-PRON-	PRP$
cord-347298-7kqrl3rv	235	18	contribution	contribution	NN
cord-347298-7kqrl3rv	235	19	to	to	IN
cord-347298-7kqrl3rv	235	20	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	235	21	is	be	VBZ
cord-347298-7kqrl3rv	235	22	probably	probably	RB
cord-347298-7kqrl3rv	235	23	marginal	marginal	JJ
cord-347298-7kqrl3rv	235	24	.	.	.
cord-347298-7kqrl3rv	236	1	Several	several	JJ
cord-347298-7kqrl3rv	236	2	lines	line	NNS
cord-347298-7kqrl3rv	236	3	of	of	IN
cord-347298-7kqrl3rv	236	4	evidence	evidence	NN
cord-347298-7kqrl3rv	236	5	indicate	indicate	VBP
cord-347298-7kqrl3rv	236	6	that	that	IN
cord-347298-7kqrl3rv	236	7	the	the	DT
cord-347298-7kqrl3rv	236	8	bloodtestis	bloodtestis	NNP
cord-347298-7kqrl3rv	236	9	barrier	barrier	NN
cord-347298-7kqrl3rv	236	10	can	can	MD
cord-347298-7kqrl3rv	236	11	not	not	RB
cord-347298-7kqrl3rv	236	12	account	account	VB
cord-347298-7kqrl3rv	236	13	for	for	IN
cord-347298-7kqrl3rv	236	14	all	all	DT
cord-347298-7kqrl3rv	236	15	manifestations	manifestation	NNS
cord-347298-7kqrl3rv	236	16	of	of	IN
cord-347298-7kqrl3rv	236	17	immune	immune	JJ
cord-347298-7kqrl3rv	236	18	privilege	privilege	NN
cord-347298-7kqrl3rv	236	19	in	in	IN
cord-347298-7kqrl3rv	236	20	the	the	DT
cord-347298-7kqrl3rv	236	21	testis	testis	NN
cord-347298-7kqrl3rv	236	22	.	.	.
cord-347298-7kqrl3rv	237	1	The	the	DT
cord-347298-7kqrl3rv	237	2	barrier	barrier	NN
cord-347298-7kqrl3rv	237	3	does	do	VBZ
cord-347298-7kqrl3rv	237	4	not	not	RB
cord-347298-7kqrl3rv	237	5	prevent	prevent	VB
cord-347298-7kqrl3rv	237	6	exposure	exposure	NN
cord-347298-7kqrl3rv	237	7	of	of	IN
cord-347298-7kqrl3rv	237	8	germ	germ	NN
cord-347298-7kqrl3rv	237	9	cell	cell	NN
cord-347298-7kqrl3rv	237	10	antigens	antigen	NNS
cord-347298-7kqrl3rv	237	11	to	to	IN
cord-347298-7kqrl3rv	237	12	the	the	DT
cord-347298-7kqrl3rv	237	13	immune	immune	JJ
cord-347298-7kqrl3rv	237	14	system	system	NN
cord-347298-7kqrl3rv	237	15	,	,	,
cord-347298-7kqrl3rv	237	16	as	as	IN
cord-347298-7kqrl3rv	237	17	antibodies	antibody	NNS
cord-347298-7kqrl3rv	237	18	and	and	CC
cord-347298-7kqrl3rv	237	19	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	237	20	specific	specific	JJ
cord-347298-7kqrl3rv	237	21	for	for	IN
cord-347298-7kqrl3rv	237	22	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	237	23	antigens	antigen	NNS
cord-347298-7kqrl3rv	237	24	appear	appear	VBP
cord-347298-7kqrl3rv	237	25	to	to	TO
cord-347298-7kqrl3rv	237	26	be	be	VB
cord-347298-7kqrl3rv	237	27	a	a	DT
cord-347298-7kqrl3rv	237	28	normal	normal	JJ
cord-347298-7kqrl3rv	237	29	feature	feature	NN
cord-347298-7kqrl3rv	237	30	of	of	IN
cord-347298-7kqrl3rv	237	31	the	the	DT
cord-347298-7kqrl3rv	237	32	circulating	circulate	VBG
cord-347298-7kqrl3rv	237	33	immune	immune	JJ
cord-347298-7kqrl3rv	237	34	repertoire	repertoire	NN
cord-347298-7kqrl3rv	237	35	even	even	RB
cord-347298-7kqrl3rv	237	36	under	under	IN
cord-347298-7kqrl3rv	237	37	normal	normal	JJ
cord-347298-7kqrl3rv	237	38	conditions	condition	NNS
cord-347298-7kqrl3rv	237	39	(	(	-LRB-
cord-347298-7kqrl3rv	237	40	Turek	Turek	NNP
cord-347298-7kqrl3rv	237	41	and	and	CC
cord-347298-7kqrl3rv	237	42	Lipshultz	Lipshultz	NNP
cord-347298-7kqrl3rv	237	43	1994	1994	CD
cord-347298-7kqrl3rv	237	44	)	)	-RRB-
cord-347298-7kqrl3rv	237	45	.	.	.
cord-347298-7kqrl3rv	238	1	Spermatogenic	Spermatogenic	NNP
cord-347298-7kqrl3rv	238	2	cell	cell	NN
cord-347298-7kqrl3rv	238	3	autoantigens	autoantigen	NNS
cord-347298-7kqrl3rv	238	4	are	be	VBP
cord-347298-7kqrl3rv	238	5	not	not	RB
cord-347298-7kqrl3rv	238	6	confined	confine	VBN
cord-347298-7kqrl3rv	238	7	behind	behind	IN
cord-347298-7kqrl3rv	238	8	the	the	DT
cord-347298-7kqrl3rv	238	9	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	238	10	cell	cell	NN
cord-347298-7kqrl3rv	238	11	tight	tight	JJ
cord-347298-7kqrl3rv	238	12	junctions	junction	NNS
cord-347298-7kqrl3rv	238	13	,	,	,
cord-347298-7kqrl3rv	238	14	and	and	CC
cord-347298-7kqrl3rv	238	15	are	be	VBP
cord-347298-7kqrl3rv	238	16	expressed	express	VBN
cord-347298-7kqrl3rv	238	17	by	by	IN
cord-347298-7kqrl3rv	238	18	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	238	19	and	and	CC
cord-347298-7kqrl3rv	238	20	the	the	DT
cord-347298-7kqrl3rv	238	21	early	early	JJ
cord-347298-7kqrl3rv	238	22	spermatocytes	spermatocytes	NNPS
cord-347298-7kqrl3rv	238	23	(	(	-LRB-
cord-347298-7kqrl3rv	238	24	Mahi-	Mahi-	NNP
cord-347298-7kqrl3rv	238	25	1988	1988	CD
cord-347298-7kqrl3rv	238	26	;	;	:
cord-347298-7kqrl3rv	238	27	Yule	Yule	NNP
cord-347298-7kqrl3rv	238	28	et	et	NNP
cord-347298-7kqrl3rv	238	29	al	al	NNP
cord-347298-7kqrl3rv	238	30	.	.	.
cord-347298-7kqrl3rv	238	31	1988	1988	CD
cord-347298-7kqrl3rv	238	32	)	)	-RRB-
cord-347298-7kqrl3rv	238	33	.	.	.
cord-347298-7kqrl3rv	239	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	239	2	,	,	,
cord-347298-7kqrl3rv	239	3	the	the	DT
cord-347298-7kqrl3rv	239	4	barrier	barrier	NN
cord-347298-7kqrl3rv	239	5	does	do	VBZ
cord-347298-7kqrl3rv	239	6	not	not	RB
cord-347298-7kqrl3rv	239	7	extend	extend	VB
cord-347298-7kqrl3rv	239	8	into	into	IN
cord-347298-7kqrl3rv	239	9	the	the	DT
cord-347298-7kqrl3rv	239	10	rete	rete	NN
cord-347298-7kqrl3rv	239	11	testis	testis	NN
cord-347298-7kqrl3rv	239	12	or	or	CC
cord-347298-7kqrl3rv	239	13	beyond	beyond	IN
cord-347298-7kqrl3rv	239	14	.	.	.
cord-347298-7kqrl3rv	240	1	Significantly	significantly	RB
cord-347298-7kqrl3rv	240	2	,	,	,
cord-347298-7kqrl3rv	240	3	orchitis	orchiti	NNS
cord-347298-7kqrl3rv	240	4	can	can	MD
cord-347298-7kqrl3rv	240	5	be	be	VB
cord-347298-7kqrl3rv	240	6	passively	passively	RB
cord-347298-7kqrl3rv	240	7	transferred	transfer	VBN
cord-347298-7kqrl3rv	240	8	to	to	IN
cord-347298-7kqrl3rv	240	9	naive	naive	JJ
cord-347298-7kqrl3rv	240	10	mice	mouse	NNS
cord-347298-7kqrl3rv	240	11	using	use	VBG
cord-347298-7kqrl3rv	240	12	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	240	13	obtained	obtain	VBN
cord-347298-7kqrl3rv	240	14	from	from	IN
cord-347298-7kqrl3rv	240	15	mice	mouse	NNS
cord-347298-7kqrl3rv	240	16	with	with	IN
cord-347298-7kqrl3rv	240	17	active	active	JJ
cord-347298-7kqrl3rv	240	18	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	240	19	orchitis	orchitis	NN
cord-347298-7kqrl3rv	240	20	,	,	,
cord-347298-7kqrl3rv	240	21	with	with	IN
cord-347298-7kqrl3rv	240	22	the	the	DT
cord-347298-7kqrl3rv	240	23	initial	initial	JJ
cord-347298-7kqrl3rv	240	24	reaction	reaction	NN
cord-347298-7kqrl3rv	240	25	concentrated	concentrate	VBN
cord-347298-7kqrl3rv	240	26	in	in	IN
cord-347298-7kqrl3rv	240	27	the	the	DT
cord-347298-7kqrl3rv	240	28	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	240	29	tissue	tissue	NN
cord-347298-7kqrl3rv	240	30	around	around	IN
cord-347298-7kqrl3rv	240	31	the	the	DT
cord-347298-7kqrl3rv	240	32	rete	rete	NN
cord-347298-7kqrl3rv	240	33	testis	testis	NN
cord-347298-7kqrl3rv	240	34	Tung	Tung	NNP
cord-347298-7kqrl3rv	240	35	et	et	FW
cord-347298-7kqrl3rv	240	36	al	al	NNP
cord-347298-7kqrl3rv	240	37	.	.	NNP
cord-347298-7kqrl3rv	240	38	1987	1987	CD
cord-347298-7kqrl3rv	240	39	)	)	-RRB-
cord-347298-7kqrl3rv	240	40	.	.	.
cord-347298-7kqrl3rv	241	1	A	a	DT
cord-347298-7kqrl3rv	241	2	similar	similar	JJ
cord-347298-7kqrl3rv	241	3	initial	initial	JJ
cord-347298-7kqrl3rv	241	4	pattern	pattern	NN
cord-347298-7kqrl3rv	241	5	of	of	IN
cord-347298-7kqrl3rv	241	6	development	development	NN
cord-347298-7kqrl3rv	241	7	of	of	IN
cord-347298-7kqrl3rv	241	8	orchitis	orchitis	NN
cord-347298-7kqrl3rv	241	9	within	within	IN
cord-347298-7kqrl3rv	241	10	the	the	DT
cord-347298-7kqrl3rv	241	11	rete	rete	NNP
cord-347298-7kqrl3rv	241	12	testis	testis	NN
cord-347298-7kqrl3rv	241	13	region	region	NN
cord-347298-7kqrl3rv	241	14	has	have	VBZ
cord-347298-7kqrl3rv	241	15	been	be	VBN
cord-347298-7kqrl3rv	241	16	observed	observe	VBN
cord-347298-7kqrl3rv	241	17	in	in	IN
cord-347298-7kqrl3rv	241	18	mice	mouse	NNS
cord-347298-7kqrl3rv	241	19	actively	actively	RB
cord-347298-7kqrl3rv	241	20	immunized	immunize	VBN
cord-347298-7kqrl3rv	241	21	with	with	IN
cord-347298-7kqrl3rv	241	22	viable	viable	JJ
cord-347298-7kqrl3rv	241	23	germ	germ	NN
cord-347298-7kqrl3rv	241	24	cells	cell	NNS
cord-347298-7kqrl3rv	241	25	(	(	-LRB-
cord-347298-7kqrl3rv	241	26	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	241	27	et	et	NNP
cord-347298-7kqrl3rv	241	28	al	al	NNP
cord-347298-7kqrl3rv	241	29	.	.	NNP
cord-347298-7kqrl3rv	241	30	1995a	1995a	CD
cord-347298-7kqrl3rv	241	31	)	)	-RRB-
cord-347298-7kqrl3rv	241	32	.	.	.
cord-347298-7kqrl3rv	242	1	In	in	IN
cord-347298-7kqrl3rv	242	2	many	many	JJ
cord-347298-7kqrl3rv	242	3	seasonally	seasonally	RB
cord-347298-7kqrl3rv	242	4	breeding	breed	VBG
cord-347298-7kqrl3rv	242	5	species	specie	NNS
cord-347298-7kqrl3rv	242	6	,	,	,
cord-347298-7kqrl3rv	242	7	annual	annual	JJ
cord-347298-7kqrl3rv	242	8	regression	regression	NN
cord-347298-7kqrl3rv	242	9	of	of	IN
cord-347298-7kqrl3rv	242	10	the	the	DT
cord-347298-7kqrl3rv	242	11	bloodtestis	bloodtestis	NNP
cord-347298-7kqrl3rv	242	12	barrier	barrier	NN
cord-347298-7kqrl3rv	242	13	occurs	occur	VBZ
cord-347298-7kqrl3rv	242	14	without	without	IN
cord-347298-7kqrl3rv	242	15	inducing	induce	VBG
cord-347298-7kqrl3rv	242	16	overt	overt	JJ
cord-347298-7kqrl3rv	242	17	inflammation	inflammation	NN
cord-347298-7kqrl3rv	242	18	or	or	CC
cord-347298-7kqrl3rv	242	19	autoimmunity	autoimmunity	NN
cord-347298-7kqrl3rv	242	20	(	(	-LRB-
cord-347298-7kqrl3rv	242	21	Pelletier	Pelletier	NNP
cord-347298-7kqrl3rv	242	22	1986	1986	CD
cord-347298-7kqrl3rv	242	23	;	;	:
cord-347298-7kqrl3rv	242	24	Tung	Tung	NNP
cord-347298-7kqrl3rv	242	25	et	et	NNP
cord-347298-7kqrl3rv	242	26	al	al	NNP
cord-347298-7kqrl3rv	242	27	.	.	NNP
cord-347298-7kqrl3rv	242	28	1981	1981	CD
cord-347298-7kqrl3rv	242	29	)	)	-RRB-
cord-347298-7kqrl3rv	242	30	.	.	.
cord-347298-7kqrl3rv	243	1	Finally	finally	RB
cord-347298-7kqrl3rv	243	2	,	,	,
cord-347298-7kqrl3rv	243	3	the	the	DT
cord-347298-7kqrl3rv	243	4	blood	blood	NN
cord-347298-7kqrl3rv	243	5	-	-	HYPH
cord-347298-7kqrl3rv	243	6	testis	testis	NN
cord-347298-7kqrl3rv	243	7	barrier	barrier	NN
cord-347298-7kqrl3rv	243	8	can	can	MD
cord-347298-7kqrl3rv	243	9	not	not	RB
cord-347298-7kqrl3rv	243	10	explain	explain	VB
cord-347298-7kqrl3rv	243	11	the	the	DT
cord-347298-7kqrl3rv	243	12	enhanced	enhance	VBN
cord-347298-7kqrl3rv	243	13	survival	survival	NN
cord-347298-7kqrl3rv	243	14	of	of	IN
cord-347298-7kqrl3rv	243	15	grafts	graft	NNS
cord-347298-7kqrl3rv	243	16	within	within	IN
cord-347298-7kqrl3rv	243	17	the	the	DT
cord-347298-7kqrl3rv	243	18	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	243	19	tissue	tissue	NN
cord-347298-7kqrl3rv	243	20	(	(	-LRB-
cord-347298-7kqrl3rv	243	21	i.e.	i.e.	FW
cord-347298-7kqrl3rv	243	22	,	,	,
cord-347298-7kqrl3rv	243	23	outside	outside	IN
cord-347298-7kqrl3rv	243	24	the	the	DT
cord-347298-7kqrl3rv	243	25	barrier	barrier	NN
cord-347298-7kqrl3rv	243	26	)	)	-RRB-
cord-347298-7kqrl3rv	243	27	and	and	CC
cord-347298-7kqrl3rv	243	28	does	do	VBZ
cord-347298-7kqrl3rv	243	29	not	not	RB
cord-347298-7kqrl3rv	243	30	explain	explain	VB
cord-347298-7kqrl3rv	243	31	survival	survival	NN
cord-347298-7kqrl3rv	243	32	of	of	IN
cord-347298-7kqrl3rv	243	33	autoantigenic	autoantigenic	JJ
cord-347298-7kqrl3rv	243	34	sperm	sperm	NN
cord-347298-7kqrl3rv	243	35	in	in	IN
cord-347298-7kqrl3rv	243	36	the	the	DT
cord-347298-7kqrl3rv	243	37	epididymis	epididymis	NN
cord-347298-7kqrl3rv	243	38	,	,	,
cord-347298-7kqrl3rv	243	39	or	or	CC
cord-347298-7kqrl3rv	243	40	remainder	remainder	NN
cord-347298-7kqrl3rv	243	41	of	of	IN
cord-347298-7kqrl3rv	243	42	the	the	DT
cord-347298-7kqrl3rv	243	43	male	male	JJ
cord-347298-7kqrl3rv	243	44	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	243	45	tract	tract	NN
cord-347298-7kqrl3rv	243	46	.	.	.
cord-347298-7kqrl3rv	244	1	However	however	RB
cord-347298-7kqrl3rv	244	2	,	,	,
cord-347298-7kqrl3rv	244	3	while	while	IN
cord-347298-7kqrl3rv	244	4	the	the	DT
cord-347298-7kqrl3rv	244	5	blood	blood	NN
cord-347298-7kqrl3rv	244	6	-	-	HYPH
cord-347298-7kqrl3rv	244	7	testis	testis	NN
cord-347298-7kqrl3rv	244	8	barrier	barrier	NN
cord-347298-7kqrl3rv	244	9	does	do	VBZ
cord-347298-7kqrl3rv	244	10	not	not	RB
cord-347298-7kqrl3rv	244	11	explain	explain	VB
cord-347298-7kqrl3rv	244	12	immune	immune	JJ
cord-347298-7kqrl3rv	244	13	privilege	privilege	NN
cord-347298-7kqrl3rv	244	14	in	in	IN
cord-347298-7kqrl3rv	244	15	the	the	DT
cord-347298-7kqrl3rv	244	16	testis	testis	NN
cord-347298-7kqrl3rv	244	17	,	,	,
cord-347298-7kqrl3rv	244	18	the	the	DT
cord-347298-7kqrl3rv	244	19	breach	breach	NN
cord-347298-7kqrl3rv	244	20	of	of	IN
cord-347298-7kqrl3rv	244	21	the	the	DT
cord-347298-7kqrl3rv	244	22	tight	tight	JJ
cord-347298-7kqrl3rv	244	23	junctions	junction	NNS
cord-347298-7kqrl3rv	244	24	comprising	comprise	VBG
cord-347298-7kqrl3rv	244	25	the	the	DT
cord-347298-7kqrl3rv	244	26	barrier	barrier	NN
cord-347298-7kqrl3rv	244	27	remains	remain	VBZ
cord-347298-7kqrl3rv	244	28	a	a	DT
cord-347298-7kqrl3rv	244	29	critical	critical	JJ
cord-347298-7kqrl3rv	244	30	event	event	NN
cord-347298-7kqrl3rv	244	31	in	in	IN
cord-347298-7kqrl3rv	244	32	the	the	DT
cord-347298-7kqrl3rv	244	33	development	development	NN
cord-347298-7kqrl3rv	244	34	of	of	IN
cord-347298-7kqrl3rv	244	35	any	any	DT
cord-347298-7kqrl3rv	244	36	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	244	37	destruction	destruction	NN
cord-347298-7kqrl3rv	244	38	of	of	IN
cord-347298-7kqrl3rv	244	39	the	the	DT
cord-347298-7kqrl3rv	244	40	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	244	41	epithelium	epithelium	NN
cord-347298-7kqrl3rv	244	42	during	during	IN
cord-347298-7kqrl3rv	244	43	orchitis	orchitis	NN
cord-347298-7kqrl3rv	244	44	(	(	-LRB-
cord-347298-7kqrl3rv	244	45	Mahi-	Mahi-	NNP
cord-347298-7kqrl3rv	244	46	Brown	Brown	NNP
cord-347298-7kqrl3rv	244	47	and	and	CC
cord-347298-7kqrl3rv	244	48	Tung	Tung	NNP
cord-347298-7kqrl3rv	244	49	1989	1989	CD
cord-347298-7kqrl3rv	245	1	;	;	:
cord-347298-7kqrl3rv	245	2	Mahi	Mahi	NNP
cord-347298-7kqrl3rv	245	3	-	-	HYPH
cord-347298-7kqrl3rv	245	4	Brown	Brown	NNP
cord-347298-7kqrl3rv	245	5	et	et	NNP
cord-347298-7kqrl3rv	245	6	al	al	NNP
cord-347298-7kqrl3rv	245	7	.	.	NNP
cord-347298-7kqrl3rv	245	8	1987	1987	CD
cord-347298-7kqrl3rv	245	9	)	)	-RRB-
cord-347298-7kqrl3rv	245	10	.	.	.
cord-347298-7kqrl3rv	246	1	Recognition	recognition	NN
cord-347298-7kqrl3rv	246	2	of	of	IN
cord-347298-7kqrl3rv	246	3	antigen	antigen	NNP
cord-347298-7kqrl3rv	246	4	in	in	IN
cord-347298-7kqrl3rv	246	5	association	association	NN
cord-347298-7kqrl3rv	246	6	with	with	IN
cord-347298-7kqrl3rv	246	7	MHC	MHC	NNP
cord-347298-7kqrl3rv	246	8	is	be	VBZ
cord-347298-7kqrl3rv	246	9	essential	essential	JJ
cord-347298-7kqrl3rv	246	10	to	to	IN
cord-347298-7kqrl3rv	246	11	normal	normal	JJ
cord-347298-7kqrl3rv	246	12	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	246	13	immune	immune	JJ
cord-347298-7kqrl3rv	246	14	responses	response	NNS
cord-347298-7kqrl3rv	246	15	,	,	,
cord-347298-7kqrl3rv	246	16	and	and	CC
cord-347298-7kqrl3rv	246	17	reduced	reduce	VBN
cord-347298-7kqrl3rv	246	18	expression	expression	NN
cord-347298-7kqrl3rv	246	19	of	of	IN
cord-347298-7kqrl3rv	246	20	MHC	MHC	NNP
cord-347298-7kqrl3rv	246	21	class	class	NN
cord-347298-7kqrl3rv	246	22	I	i	NN
cord-347298-7kqrl3rv	246	23	(	(	-LRB-
cord-347298-7kqrl3rv	246	24	HLA	HLA	NNP
cord-347298-7kqrl3rv	246	25	-	-	HYPH
cord-347298-7kqrl3rv	246	26	A	A	NNP
cord-347298-7kqrl3rv	246	27	,	,	,
cord-347298-7kqrl3rv	246	28	HLA	HLA	NNP
cord-347298-7kqrl3rv	246	29	-	-	HYPH
cord-347298-7kqrl3rv	246	30	B	B	NNP
cord-347298-7kqrl3rv	246	31	,	,	,
cord-347298-7kqrl3rv	246	32	and	and	CC
cord-347298-7kqrl3rv	246	33	HLA	HLA	NNP
cord-347298-7kqrl3rv	246	34	-	-	HYPH
cord-347298-7kqrl3rv	246	35	C	C	NNP
cord-347298-7kqrl3rv	246	36	in	in	IN
cord-347298-7kqrl3rv	246	37	humans	human	NNS
cord-347298-7kqrl3rv	246	38	)	)	-RRB-
cord-347298-7kqrl3rv	246	39	and	and	CC
cord-347298-7kqrl3rv	246	40	class	class	NN
cord-347298-7kqrl3rv	246	41	II	ii	NN
cord-347298-7kqrl3rv	246	42	proteins	protein	NNS
cord-347298-7kqrl3rv	246	43	(	(	-LRB-
cord-347298-7kqrl3rv	246	44	HLA	HLA	NNP
cord-347298-7kqrl3rv	246	45	-	-	HYPH
cord-347298-7kqrl3rv	246	46	D	D	NNP
cord-347298-7kqrl3rv	246	47	)	)	-RRB-
cord-347298-7kqrl3rv	246	48	appears	appear	VBZ
cord-347298-7kqrl3rv	246	49	to	to	TO
cord-347298-7kqrl3rv	246	50	be	be	VB
cord-347298-7kqrl3rv	246	51	an	an	DT
cord-347298-7kqrl3rv	246	52	important	important	JJ
cord-347298-7kqrl3rv	246	53	feature	feature	NN
cord-347298-7kqrl3rv	246	54	of	of	IN
cord-347298-7kqrl3rv	246	55	immune	immune	NN
cord-347298-7kqrl3rv	246	56	-	-	HYPH
cord-347298-7kqrl3rv	246	57	privileged	privileged	JJ
cord-347298-7kqrl3rv	246	58	tissues	tissue	NNS
cord-347298-7kqrl3rv	246	59	and	and	CC
cord-347298-7kqrl3rv	246	60	tumors	tumor	NNS
cord-347298-7kqrl3rv	246	61	(	(	-LRB-
cord-347298-7kqrl3rv	246	62	Garrido	Garrido	NNP
cord-347298-7kqrl3rv	246	63	et	et	NNP
cord-347298-7kqrl3rv	246	64	al	al	NNP
cord-347298-7kqrl3rv	246	65	.	.	.
cord-347298-7kqrl3rv	246	66	1997	1997	CD
cord-347298-7kqrl3rv	246	67	;	;	:
cord-347298-7kqrl3rv	246	68	Haas	Haas	NNP
cord-347298-7kqrl3rv	246	69	et	et	FW
cord-347298-7kqrl3rv	246	70	al	al	NNP
cord-347298-7kqrl3rv	246	71	.	.	.
cord-347298-7kqrl3rv	247	1	1988	1988	CD
cord-347298-7kqrl3rv	247	2	;	;	:
cord-347298-7kqrl3rv	247	3	Head	Head	NNP
cord-347298-7kqrl3rv	247	4	and	and	CC
cord-347298-7kqrl3rv	247	5	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	247	6	1985	1985	CD
cord-347298-7kqrl3rv	247	7	;	;	:
cord-347298-7kqrl3rv	247	8	Wekerle	Wekerle	NNP
cord-347298-7kqrl3rv	247	9	et	et	NNP
cord-347298-7kqrl3rv	247	10	al	al	NNP
cord-347298-7kqrl3rv	247	11	.	.	NNP
cord-347298-7kqrl3rv	247	12	1987	1987	CD
cord-347298-7kqrl3rv	247	13	)	)	-RRB-
cord-347298-7kqrl3rv	247	14	.	.	.
cord-347298-7kqrl3rv	248	1	Reduction	reduction	NN
cord-347298-7kqrl3rv	248	2	in	in	IN
cord-347298-7kqrl3rv	248	3	class	class	NN
cord-347298-7kqrl3rv	248	4	I	i	NN
cord-347298-7kqrl3rv	248	5	and	and	CC
cord-347298-7kqrl3rv	248	6	II	II	NNP
cord-347298-7kqrl3rv	248	7	expression	expression	NN
cord-347298-7kqrl3rv	248	8	reduces	reduce	VBZ
cord-347298-7kqrl3rv	248	9	the	the	DT
cord-347298-7kqrl3rv	248	10	likelihood	likelihood	NN
cord-347298-7kqrl3rv	248	11	of	of	IN
cord-347298-7kqrl3rv	248	12	immune	immune	NN
cord-347298-7kqrl3rv	248	13	-	-	HYPH
cord-347298-7kqrl3rv	248	14	activating	activate	VBG
cord-347298-7kqrl3rv	248	15	events	event	NNS
cord-347298-7kqrl3rv	248	16	involving	involve	VBG
cord-347298-7kqrl3rv	248	17	CD4	CD4	NNP
cord-347298-7kqrl3rv	248	18	þ	þ	NNP
cord-347298-7kqrl3rv	248	19	helper	helper	NN
cord-347298-7kqrl3rv	248	20	T	t	NN
cord-347298-7kqrl3rv	248	21	cells	cell	NNS
cord-347298-7kqrl3rv	248	22	and	and	CC
cord-347298-7kqrl3rv	248	23	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	248	24	CD8	CD8	NNP
cord-347298-7kqrl3rv	248	25	þ	þ	NNP
cord-347298-7kqrl3rv	248	26	T	T	NNP
cord-347298-7kqrl3rv	248	27	cells	cell	NNS
cord-347298-7kqrl3rv	248	28	in	in	IN
cord-347298-7kqrl3rv	248	29	the	the	DT
cord-347298-7kqrl3rv	248	30	tissues	tissue	NNS
cord-347298-7kqrl3rv	248	31	.	.	.
cord-347298-7kqrl3rv	249	1	Studies	study	NNS
cord-347298-7kqrl3rv	249	2	indicate	indicate	VBP
cord-347298-7kqrl3rv	249	3	a	a	DT
cord-347298-7kqrl3rv	249	4	characteristic	characteristic	JJ
cord-347298-7kqrl3rv	249	5	absence	absence	NN
cord-347298-7kqrl3rv	249	6	of	of	IN
cord-347298-7kqrl3rv	249	7	expression	expression	NN
cord-347298-7kqrl3rv	249	8	of	of	IN
cord-347298-7kqrl3rv	249	9	MHC	MHC	NNP
cord-347298-7kqrl3rv	249	10	proteins	protein	NNS
cord-347298-7kqrl3rv	249	11	on	on	IN
cord-347298-7kqrl3rv	249	12	the	the	DT
cord-347298-7kqrl3rv	249	13	cells	cell	NNS
cord-347298-7kqrl3rv	249	14	of	of	IN
cord-347298-7kqrl3rv	249	15	the	the	DT
cord-347298-7kqrl3rv	249	16	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	249	17	epithelium	epithelium	NN
cord-347298-7kqrl3rv	249	18	under	under	IN
cord-347298-7kqrl3rv	249	19	normal	normal	JJ
cord-347298-7kqrl3rv	249	20	conditions	condition	NNS
cord-347298-7kqrl3rv	249	21	(	(	-LRB-
cord-347298-7kqrl3rv	249	22	Haas	Haas	NNP
cord-347298-7kqrl3rv	249	23	et	et	NNP
cord-347298-7kqrl3rv	249	24	al	al	NNP
cord-347298-7kqrl3rv	249	25	.	.	.
cord-347298-7kqrl3rv	249	26	1988	1988	CD
cord-347298-7kqrl3rv	249	27	;	;	:
cord-347298-7kqrl3rv	249	28	Head	Head	NNP
cord-347298-7kqrl3rv	249	29	and	and	CC
cord-347298-7kqrl3rv	249	30	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	249	31	1985	1985	CD
cord-347298-7kqrl3rv	249	32	;	;	:
cord-347298-7kqrl3rv	249	33	Lustig	Lustig	NNP
cord-347298-7kqrl3rv	249	34	et	et	NNP
cord-347298-7kqrl3rv	249	35	al	al	NNP
cord-347298-7kqrl3rv	249	36	.	.	NNP
cord-347298-7kqrl3rv	249	37	1993	1993	CD
cord-347298-7kqrl3rv	249	38	;	;	.
cord-347298-7kqrl3rv	250	1	Tung	Tung	NNP
cord-347298-7kqrl3rv	250	2	et	et	NNP
cord-347298-7kqrl3rv	250	3	al	al	NNP
cord-347298-7kqrl3rv	250	4	.	.	NNP
cord-347298-7kqrl3rv	250	5	1987	1987	CD
cord-347298-7kqrl3rv	250	6	)	)	-RRB-
cord-347298-7kqrl3rv	250	7	,	,	,
cord-347298-7kqrl3rv	250	8	although	although	IN
cord-347298-7kqrl3rv	250	9	both	both	DT
cord-347298-7kqrl3rv	250	10	MHC	MHC	NNP
cord-347298-7kqrl3rv	250	11	classes	class	NNS
cord-347298-7kqrl3rv	250	12	are	be	VBP
cord-347298-7kqrl3rv	250	13	expressed	express	VBN
cord-347298-7kqrl3rv	250	14	in	in	IN
cord-347298-7kqrl3rv	250	15	human	human	JJ
cord-347298-7kqrl3rv	250	16	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	250	17	(	(	-LRB-
cord-347298-7kqrl3rv	250	18	Martín	Martín	NNP
cord-347298-7kqrl3rv	250	19	-	-	HYPH
cord-347298-7kqrl3rv	250	20	Villa	Villa	NNP
cord-347298-7kqrl3rv	250	21	et	et	NNP
cord-347298-7kqrl3rv	250	22	al	al	NNP
cord-347298-7kqrl3rv	250	23	.	.	.
cord-347298-7kqrl3rv	250	24	1996	1996	CD
cord-347298-7kqrl3rv	250	25	)	)	-RRB-
cord-347298-7kqrl3rv	250	26	.	.	.
cord-347298-7kqrl3rv	251	1	There	there	EX
cord-347298-7kqrl3rv	251	2	is	be	VBZ
cord-347298-7kqrl3rv	251	3	evidence	evidence	NN
cord-347298-7kqrl3rv	251	4	from	from	IN
cord-347298-7kqrl3rv	251	5	studies	study	NNS
cord-347298-7kqrl3rv	251	6	on	on	IN
cord-347298-7kqrl3rv	251	7	mouse	mouse	NN
cord-347298-7kqrl3rv	251	8	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	251	9	cells	cell	NNS
cord-347298-7kqrl3rv	251	10	in	in	IN
cord-347298-7kqrl3rv	251	11	culture	culture	NN
cord-347298-7kqrl3rv	251	12	that	that	WDT
cord-347298-7kqrl3rv	251	13	MHC	MHC	NNP
cord-347298-7kqrl3rv	251	14	class	class	NN
cord-347298-7kqrl3rv	251	15	II	II	NNP
cord-347298-7kqrl3rv	251	16	expression	expression	NN
cord-347298-7kqrl3rv	251	17	can	can	MD
cord-347298-7kqrl3rv	251	18	be	be	VB
cord-347298-7kqrl3rv	251	19	upregulated	upregulate	VBN
cord-347298-7kqrl3rv	251	20	in	in	IN
cord-347298-7kqrl3rv	251	21	these	these	DT
cord-347298-7kqrl3rv	251	22	cells	cell	NNS
cord-347298-7kqrl3rv	251	23	by	by	IN
cord-347298-7kqrl3rv	251	24	IFN	IFN	NNP
cord-347298-7kqrl3rv	251	25	(	(	-LRB-
cord-347298-7kqrl3rv	251	26	Dal	Dal	NNP
cord-347298-7kqrl3rv	251	27	Secco	Secco	NNP
cord-347298-7kqrl3rv	251	28	et	et	FW
cord-347298-7kqrl3rv	251	29	al	al	NNP
cord-347298-7kqrl3rv	251	30	.	.	NNP
cord-347298-7kqrl3rv	251	31	2008	2008	CD
cord-347298-7kqrl3rv	251	32	)	)	-RRB-
cord-347298-7kqrl3rv	251	33	.	.	.
cord-347298-7kqrl3rv	252	1	In	in	IN
cord-347298-7kqrl3rv	252	2	contrast	contrast	NN
cord-347298-7kqrl3rv	252	3	to	to	IN
cord-347298-7kqrl3rv	252	4	the	the	DT
cord-347298-7kqrl3rv	252	5	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	252	6	epithelium	epithelium	NN
cord-347298-7kqrl3rv	252	7	,	,	,
cord-347298-7kqrl3rv	252	8	both	both	DT
cord-347298-7kqrl3rv	252	9	MHC	MHC	NNP
cord-347298-7kqrl3rv	252	10	class	class	NN
cord-347298-7kqrl3rv	252	11	I	i	NN
cord-347298-7kqrl3rv	252	12	and	and	CC
cord-347298-7kqrl3rv	252	13	II	II	NNP
cord-347298-7kqrl3rv	252	14	proteins	protein	NNS
cord-347298-7kqrl3rv	252	15	are	be	VBP
cord-347298-7kqrl3rv	252	16	expressed	express	VBN
cord-347298-7kqrl3rv	252	17	throughout	throughout	IN
cord-347298-7kqrl3rv	252	18	the	the	DT
cord-347298-7kqrl3rv	252	19	testicular	testicular	JJ
cord-347298-7kqrl3rv	252	20	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	252	21	tissue	tissue	NN
cord-347298-7kqrl3rv	252	22	:	:	:
cord-347298-7kqrl3rv	252	23	MHC	MHC	NNP
cord-347298-7kqrl3rv	252	24	class	class	NN
cord-347298-7kqrl3rv	252	25	I	-PRON-	PRP
cord-347298-7kqrl3rv	252	26	is	be	VBZ
cord-347298-7kqrl3rv	252	27	expressed	express	VBN
cord-347298-7kqrl3rv	252	28	on	on	IN
cord-347298-7kqrl3rv	252	29	most	most	JJS
cord-347298-7kqrl3rv	252	30	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	252	31	cells	cell	NNS
cord-347298-7kqrl3rv	252	32	,	,	,
cord-347298-7kqrl3rv	252	33	including	include	VBG
cord-347298-7kqrl3rv	252	34	the	the	DT
cord-347298-7kqrl3rv	252	35	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	252	36	cells	cell	NNS
cord-347298-7kqrl3rv	252	37	(	(	-LRB-
cord-347298-7kqrl3rv	252	38	Haas	Haas	NNP
cord-347298-7kqrl3rv	252	39	et	et	NNP
cord-347298-7kqrl3rv	252	40	al	al	NNP
cord-347298-7kqrl3rv	252	41	.	.	.
cord-347298-7kqrl3rv	252	42	1988	1988	CD
cord-347298-7kqrl3rv	252	43	;	;	:
cord-347298-7kqrl3rv	252	44	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	252	45	and	and	CC
cord-347298-7kqrl3rv	252	46	Maddocks	Maddocks	NNP
cord-347298-7kqrl3rv	252	47	1988	1988	CD
cord-347298-7kqrl3rv	252	48	)	)	-RRB-
cord-347298-7kqrl3rv	252	49	,	,	,
cord-347298-7kqrl3rv	252	50	while	while	IN
cord-347298-7kqrl3rv	252	51	testicular	testicular	JJ
cord-347298-7kqrl3rv	252	52	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	252	53	and	and	CC
cord-347298-7kqrl3rv	252	54	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	252	55	cells	cell	NNS
cord-347298-7kqrl3rv	252	56	express	express	VBP
cord-347298-7kqrl3rv	252	57	MHC	MHC	NNP
cord-347298-7kqrl3rv	252	58	class	class	NN
cord-347298-7kqrl3rv	252	59	II	II	NNP
cord-347298-7kqrl3rv	253	1	(	(	-LRB-
cord-347298-7kqrl3rv	253	2	Haas	Haas	NNP
cord-347298-7kqrl3rv	253	3	et	et	NNP
cord-347298-7kqrl3rv	253	4	al	al	NNP
cord-347298-7kqrl3rv	253	5	.	.	.
cord-347298-7kqrl3rv	254	1	1988	1988	CD
cord-347298-7kqrl3rv	254	2	;	;	:
cord-347298-7kqrl3rv	254	3	Head	Head	NNP
cord-347298-7kqrl3rv	254	4	and	and	CC
cord-347298-7kqrl3rv	254	5	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	254	6	1985	1985	CD
cord-347298-7kqrl3rv	254	7	;	;	:
cord-347298-7kqrl3rv	254	8	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	254	9	and	and	CC
cord-347298-7kqrl3rv	254	10	Eddy	Eddy	NNP
cord-347298-7kqrl3rv	254	11	1987	1987	CD
cord-347298-7kqrl3rv	254	12	;	;	:
cord-347298-7kqrl3rv	254	13	Mahi	Mahi	NNP
cord-347298-7kqrl3rv	254	14	-	-	HYPH
cord-347298-7kqrl3rv	254	15	Brown	Brown	NNP
cord-347298-7kqrl3rv	254	16	et	et	NNP
cord-347298-7kqrl3rv	254	17	al	al	NNP
cord-347298-7kqrl3rv	254	18	.	.	NNP
cord-347298-7kqrl3rv	254	19	1987	1987	CD
cord-347298-7kqrl3rv	254	20	;	;	:
cord-347298-7kqrl3rv	254	21	Tung	Tung	NNP
cord-347298-7kqrl3rv	254	22	et	et	NNP
cord-347298-7kqrl3rv	254	23	al	al	NNP
cord-347298-7kqrl3rv	254	24	.	.	NNP
cord-347298-7kqrl3rv	254	25	1987	1987	CD
cord-347298-7kqrl3rv	254	26	)	)	-RRB-
cord-347298-7kqrl3rv	254	27	.	.	.
cord-347298-7kqrl3rv	255	1	Thus	thus	RB
cord-347298-7kqrl3rv	255	2	,	,	,
cord-347298-7kqrl3rv	255	3	it	-PRON-	PRP
cord-347298-7kqrl3rv	255	4	appears	appear	VBZ
cord-347298-7kqrl3rv	255	5	unlikely	unlikely	JJ
cord-347298-7kqrl3rv	255	6	that	that	IN
cord-347298-7kqrl3rv	255	7	a	a	DT
cord-347298-7kqrl3rv	255	8	lack	lack	NN
cord-347298-7kqrl3rv	255	9	of	of	IN
cord-347298-7kqrl3rv	255	10	APCs	apc	NNS
cord-347298-7kqrl3rv	255	11	is	be	VBZ
cord-347298-7kqrl3rv	255	12	a	a	DT
cord-347298-7kqrl3rv	255	13	contributing	contribute	VBG
cord-347298-7kqrl3rv	255	14	factor	factor	NN
cord-347298-7kqrl3rv	255	15	in	in	IN
cord-347298-7kqrl3rv	255	16	testicular	testicular	JJ
cord-347298-7kqrl3rv	255	17	immune	immune	JJ
cord-347298-7kqrl3rv	255	18	privilege	privilege	NN
cord-347298-7kqrl3rv	255	19	,	,	,
cord-347298-7kqrl3rv	255	20	although	although	IN
cord-347298-7kqrl3rv	255	21	differences	difference	NNS
cord-347298-7kqrl3rv	255	22	in	in	IN
cord-347298-7kqrl3rv	255	23	the	the	DT
cord-347298-7kqrl3rv	255	24	number	number	NN
cord-347298-7kqrl3rv	255	25	and	and	CC
cord-347298-7kqrl3rv	255	26	distribution	distribution	NN
cord-347298-7kqrl3rv	255	27	of	of	IN
cord-347298-7kqrl3rv	255	28	MHC	MHC	NNP
cord-347298-7kqrl3rv	255	29	class	class	NN
cord-347298-7kqrl3rv	255	30	II	II	NNP
cord-347298-7kqrl3rv	255	31	-	-	HYPH
cord-347298-7kqrl3rv	255	32	expressing	express	VBG
cord-347298-7kqrl3rv	255	33	cells	cell	NNS
cord-347298-7kqrl3rv	255	34	in	in	IN
cord-347298-7kqrl3rv	255	35	the	the	DT
cord-347298-7kqrl3rv	255	36	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	255	37	tissue	tissue	NN
cord-347298-7kqrl3rv	255	38	of	of	IN
cord-347298-7kqrl3rv	255	39	different	different	JJ
cord-347298-7kqrl3rv	255	40	species	specie	NNS
cord-347298-7kqrl3rv	255	41	or	or	CC
cord-347298-7kqrl3rv	255	42	strains	strain	NNS
cord-347298-7kqrl3rv	255	43	may	may	MD
cord-347298-7kqrl3rv	255	44	help	help	VB
cord-347298-7kqrl3rv	255	45	to	to	TO
cord-347298-7kqrl3rv	255	46	explain	explain	VB
cord-347298-7kqrl3rv	255	47	differences	difference	NNS
cord-347298-7kqrl3rv	255	48	in	in	IN
cord-347298-7kqrl3rv	255	49	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	255	50	to	to	IN
cord-347298-7kqrl3rv	255	51	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	255	52	orchitis	orchitis	NN
cord-347298-7kqrl3rv	256	1	(	(	-LRB-
cord-347298-7kqrl3rv	256	2	Flickinger	Flickinger	NNP
cord-347298-7kqrl3rv	256	3	et	et	NNP
cord-347298-7kqrl3rv	256	4	al	al	NNP
cord-347298-7kqrl3rv	256	5	.	.	.
cord-347298-7kqrl3rv	257	1	1990b	1990b	CD
cord-347298-7kqrl3rv	257	2	;	;	:
cord-347298-7kqrl3rv	257	3	Kojima	Kojima	NNP
cord-347298-7kqrl3rv	257	4	and	and	CC
cord-347298-7kqrl3rv	257	5	Spencer	Spencer	NNP
cord-347298-7kqrl3rv	257	6	1983	1983	CD
cord-347298-7kqrl3rv	257	7	;	;	:
cord-347298-7kqrl3rv	257	8	Teuscher	Teuscher	NNP
cord-347298-7kqrl3rv	257	9	et	et	NNP
cord-347298-7kqrl3rv	257	10	al	al	NNP
cord-347298-7kqrl3rv	257	11	.	.	NNP
cord-347298-7kqrl3rv	257	12	1987	1987	CD
cord-347298-7kqrl3rv	257	13	)	)	-RRB-
cord-347298-7kqrl3rv	257	14	.	.	.
cord-347298-7kqrl3rv	258	1	The	the	DT
cord-347298-7kqrl3rv	258	2	fact	fact	NN
cord-347298-7kqrl3rv	258	3	that	that	IN
cord-347298-7kqrl3rv	258	4	the	the	DT
cord-347298-7kqrl3rv	258	5	testis	testis	NN
cord-347298-7kqrl3rv	258	6	is	be	VBZ
cord-347298-7kqrl3rv	258	7	not	not	RB
cord-347298-7kqrl3rv	258	8	isolated	isolate	VBN
cord-347298-7kqrl3rv	258	9	from	from	IN
cord-347298-7kqrl3rv	258	10	the	the	DT
cord-347298-7kqrl3rv	258	11	immune	immune	JJ
cord-347298-7kqrl3rv	258	12	system	system	NN
cord-347298-7kqrl3rv	258	13	,	,	,
cord-347298-7kqrl3rv	258	14	yet	yet	CC
cord-347298-7kqrl3rv	258	15	can	can	MD
cord-347298-7kqrl3rv	258	16	tolerate	tolerate	VB
cord-347298-7kqrl3rv	258	17	both	both	DT
cord-347298-7kqrl3rv	258	18	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	258	19	(	(	-LRB-
cord-347298-7kqrl3rv	258	20	auto-	auto-	NNS
cord-347298-7kqrl3rv	258	21	)	)	-RRB-
cord-347298-7kqrl3rv	258	22	antigens	antigen	NNS
cord-347298-7kqrl3rv	258	23	associated	associate	VBN
cord-347298-7kqrl3rv	258	24	with	with	IN
cord-347298-7kqrl3rv	258	25	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	258	26	and	and	CC
cord-347298-7kqrl3rv	258	27	exogenous	exogenous	JJ
cord-347298-7kqrl3rv	258	28	(	(	-LRB-
cord-347298-7kqrl3rv	258	29	allo	allo	NN
cord-347298-7kqrl3rv	258	30	-	-	HYPH
cord-347298-7kqrl3rv	258	31	or	or	CC
cord-347298-7kqrl3rv	258	32	xeno-	xeno-	NN
cord-347298-7kqrl3rv	258	33	)	)	-RRB-
cord-347298-7kqrl3rv	258	34	antigens	antigen	NNS
cord-347298-7kqrl3rv	258	35	expressed	express	VBN
cord-347298-7kqrl3rv	258	36	by	by	IN
cord-347298-7kqrl3rv	258	37	grafts	graft	NNS
cord-347298-7kqrl3rv	258	38	,	,	,
cord-347298-7kqrl3rv	258	39	is	be	VBZ
cord-347298-7kqrl3rv	258	40	evidence	evidence	NN
cord-347298-7kqrl3rv	258	41	of	of	IN
cord-347298-7kqrl3rv	258	42	tissue	tissue	NN
cord-347298-7kqrl3rv	258	43	-	-	HYPH
cord-347298-7kqrl3rv	258	44	specific	specific	JJ
cord-347298-7kqrl3rv	258	45	inhibition	inhibition	NN
cord-347298-7kqrl3rv	258	46	of	of	IN
cord-347298-7kqrl3rv	258	47	the	the	DT
cord-347298-7kqrl3rv	258	48	immune	immune	JJ
cord-347298-7kqrl3rv	258	49	response	response	NN
cord-347298-7kqrl3rv	258	50	.	.	.
cord-347298-7kqrl3rv	259	1	The	the	DT
cord-347298-7kqrl3rv	259	2	question	question	NN
cord-347298-7kqrl3rv	259	3	then	then	RB
cord-347298-7kqrl3rv	259	4	arises	arise	VBZ
cord-347298-7kqrl3rv	259	5	:	:	:
cord-347298-7kqrl3rv	259	6	if	if	IN
cord-347298-7kqrl3rv	259	7	immune	immune	JJ
cord-347298-7kqrl3rv	259	8	responses	response	NNS
cord-347298-7kqrl3rv	259	9	against	against	IN
cord-347298-7kqrl3rv	259	10	exogenous	exogenous	JJ
cord-347298-7kqrl3rv	259	11	and	and	CC
cord-347298-7kqrl3rv	259	12	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	259	13	antigens	antigen	NNS
cord-347298-7kqrl3rv	259	14	are	be	VBP
cord-347298-7kqrl3rv	259	15	inhibited	inhibit	VBN
cord-347298-7kqrl3rv	259	16	in	in	IN
cord-347298-7kqrl3rv	259	17	the	the	DT
cord-347298-7kqrl3rv	259	18	testis	testis	NN
cord-347298-7kqrl3rv	259	19	environment	environment	NN
cord-347298-7kqrl3rv	259	20	,	,	,
cord-347298-7kqrl3rv	259	21	does	do	VBZ
cord-347298-7kqrl3rv	259	22	the	the	DT
cord-347298-7kqrl3rv	259	23	testis	testis	NN
cord-347298-7kqrl3rv	259	24	display	display	NN
cord-347298-7kqrl3rv	259	25	a	a	DT
cord-347298-7kqrl3rv	259	26	reduced	reduce	VBN
cord-347298-7kqrl3rv	259	27	capacity	capacity	NN
cord-347298-7kqrl3rv	259	28	to	to	TO
cord-347298-7kqrl3rv	259	29	deal	deal	VB
cord-347298-7kqrl3rv	259	30	with	with	IN
cord-347298-7kqrl3rv	259	31	infections	infection	NNS
cord-347298-7kqrl3rv	259	32	and	and	CC
cord-347298-7kqrl3rv	259	33	greater	great	JJR
cord-347298-7kqrl3rv	259	34	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	259	35	to	to	IN
cord-347298-7kqrl3rv	259	36	certain	certain	JJ
cord-347298-7kqrl3rv	259	37	kinds	kind	NNS
cord-347298-7kqrl3rv	259	38	of	of	IN
cord-347298-7kqrl3rv	259	39	tumors	tumor	NNS
cord-347298-7kqrl3rv	259	40	?	?	.
cord-347298-7kqrl3rv	260	1	There	there	EX
cord-347298-7kqrl3rv	260	2	is	be	VBZ
cord-347298-7kqrl3rv	260	3	evidence	evidence	NN
cord-347298-7kqrl3rv	260	4	that	that	IN
cord-347298-7kqrl3rv	260	5	immunity	immunity	NN
cord-347298-7kqrl3rv	260	6	may	may	MD
cord-347298-7kqrl3rv	260	7	be	be	VB
cord-347298-7kqrl3rv	260	8	compromised	compromise	VBN
cord-347298-7kqrl3rv	260	9	in	in	IN
cord-347298-7kqrl3rv	260	10	some	some	DT
cord-347298-7kqrl3rv	260	11	situations	situation	NNS
cord-347298-7kqrl3rv	260	12	,	,	,
cord-347298-7kqrl3rv	260	13	for	for	IN
cord-347298-7kqrl3rv	260	14	example	example	NN
cord-347298-7kqrl3rv	260	15	,	,	,
cord-347298-7kqrl3rv	260	16	the	the	DT
cord-347298-7kqrl3rv	260	17	tendency	tendency	NN
cord-347298-7kqrl3rv	260	18	toward	toward	IN
cord-347298-7kqrl3rv	260	19	relapsing	relapse	VBG
cord-347298-7kqrl3rv	260	20	acute	acute	JJ
cord-347298-7kqrl3rv	260	21	lymphocytic	lymphocytic	JJ
cord-347298-7kqrl3rv	260	22	leukemia	leukemia	NN
cord-347298-7kqrl3rv	260	23	in	in	IN
cord-347298-7kqrl3rv	260	24	the	the	DT
cord-347298-7kqrl3rv	260	25	testes	testis	NNS
cord-347298-7kqrl3rv	260	26	(	(	-LRB-
cord-347298-7kqrl3rv	260	27	Hudson	Hudson	NNP
cord-347298-7kqrl3rv	260	28	et	et	NNP
cord-347298-7kqrl3rv	260	29	al	al	NNP
cord-347298-7kqrl3rv	260	30	.	.	.
cord-347298-7kqrl3rv	260	31	1985	1985	CD
cord-347298-7kqrl3rv	260	32	)	)	-RRB-
cord-347298-7kqrl3rv	260	33	,	,	,
cord-347298-7kqrl3rv	260	34	and	and	CC
cord-347298-7kqrl3rv	260	35	several	several	JJ
cord-347298-7kqrl3rv	260	36	systemic	systemic	JJ
cord-347298-7kqrl3rv	260	37	viral	viral	JJ
cord-347298-7kqrl3rv	260	38	and	and	CC
cord-347298-7kqrl3rv	260	39	mycobacterial	mycobacterial	JJ
cord-347298-7kqrl3rv	260	40	infections	infection	NNS
cord-347298-7kqrl3rv	260	41	target	target	VBP
cord-347298-7kqrl3rv	260	42	the	the	DT
cord-347298-7kqrl3rv	260	43	testis	testis	NN
cord-347298-7kqrl3rv	260	44	,	,	,
cord-347298-7kqrl3rv	260	45	including	include	VBG
cord-347298-7kqrl3rv	260	46	mumps	mumps	NN
cord-347298-7kqrl3rv	260	47	,	,	,
cord-347298-7kqrl3rv	260	48	human	human	JJ
cord-347298-7kqrl3rv	260	49	immunodeficiency	immunodeficiency	NN
cord-347298-7kqrl3rv	260	50	virus	virus	NN
cord-347298-7kqrl3rv	260	51	,	,	,
cord-347298-7kqrl3rv	260	52	tuberculosis	tuberculosis	NN
cord-347298-7kqrl3rv	260	53	,	,	,
cord-347298-7kqrl3rv	260	54	and	and	CC
cord-347298-7kqrl3rv	260	55	the	the	DT
cord-347298-7kqrl3rv	260	56	severe	severe	JJ
cord-347298-7kqrl3rv	260	57	acute	acute	JJ
cord-347298-7kqrl3rv	260	58	respiratory	respiratory	JJ
cord-347298-7kqrl3rv	260	59	syndrome	syndrome	NN
cord-347298-7kqrl3rv	260	60	virus	virus	NN
cord-347298-7kqrl3rv	260	61	(	(	-LRB-
cord-347298-7kqrl3rv	260	62	Krieger	Krieger	NNP
cord-347298-7kqrl3rv	260	63	1984	1984	CD
cord-347298-7kqrl3rv	260	64	;	;	:
cord-347298-7kqrl3rv	260	65	Nistal	Nistal	NNP
cord-347298-7kqrl3rv	260	66	et	et	NNP
cord-347298-7kqrl3rv	260	67	al	al	NNP
cord-347298-7kqrl3rv	260	68	.	.	NNP
cord-347298-7kqrl3rv	260	69	1986	1986	CD
cord-347298-7kqrl3rv	260	70	;	;	:
cord-347298-7kqrl3rv	260	71	Xu	Xu	NNP
cord-347298-7kqrl3rv	260	72	et	et	NNP
cord-347298-7kqrl3rv	260	73	al	al	NNP
cord-347298-7kqrl3rv	260	74	.	.	.
cord-347298-7kqrl3rv	260	75	2006	2006	CD
cord-347298-7kqrl3rv	260	76	)	)	-RRB-
cord-347298-7kqrl3rv	260	77	.	.	.
cord-347298-7kqrl3rv	261	1	However	however	RB
cord-347298-7kqrl3rv	261	2	,	,	,
cord-347298-7kqrl3rv	261	3	the	the	DT
cord-347298-7kqrl3rv	261	4	testis	testis	NN
cord-347298-7kqrl3rv	261	5	does	do	VBZ
cord-347298-7kqrl3rv	261	6	not	not	RB
cord-347298-7kqrl3rv	261	7	appear	appear	VB
cord-347298-7kqrl3rv	261	8	to	to	TO
cord-347298-7kqrl3rv	261	9	be	be	VB
cord-347298-7kqrl3rv	261	10	immunodeficient	immunodeficient	JJ
cord-347298-7kqrl3rv	261	11	.	.	.
cord-347298-7kqrl3rv	262	1	Even	even	RB
cord-347298-7kqrl3rv	262	2	in	in	IN
cord-347298-7kqrl3rv	262	3	comparison	comparison	NN
cord-347298-7kqrl3rv	262	4	with	with	IN
cord-347298-7kqrl3rv	262	5	the	the	DT
cord-347298-7kqrl3rv	262	6	rest	rest	NN
cord-347298-7kqrl3rv	262	7	of	of	IN
cord-347298-7kqrl3rv	262	8	the	the	DT
cord-347298-7kqrl3rv	262	9	male	male	JJ
cord-347298-7kqrl3rv	262	10	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	262	11	tract	tract	NN
cord-347298-7kqrl3rv	262	12	,	,	,
cord-347298-7kqrl3rv	262	13	orchitis	orchitis	NN
cord-347298-7kqrl3rv	262	14	due	due	JJ
cord-347298-7kqrl3rv	262	15	to	to	IN
cord-347298-7kqrl3rv	262	16	ascending	ascend	VBG
cord-347298-7kqrl3rv	262	17	infections	infection	NNS
cord-347298-7kqrl3rv	262	18	is	be	VBZ
cord-347298-7kqrl3rv	262	19	relatively	relatively	RB
cord-347298-7kqrl3rv	262	20	rare	rare	JJ
cord-347298-7kqrl3rv	262	21	(	(	-LRB-
cord-347298-7kqrl3rv	262	22	Krieger	Krieger	NNP
cord-347298-7kqrl3rv	262	23	1984	1984	CD
cord-347298-7kqrl3rv	262	24	;	;	:
cord-347298-7kqrl3rv	262	25	Ness	Ness	NNP
cord-347298-7kqrl3rv	262	26	et	et	NNP
cord-347298-7kqrl3rv	262	27	al	al	NNP
cord-347298-7kqrl3rv	262	28	.	.	.
cord-347298-7kqrl3rv	262	29	1997	1997	CD
cord-347298-7kqrl3rv	262	30	)	)	-RRB-
cord-347298-7kqrl3rv	262	31	.	.	.
cord-347298-7kqrl3rv	263	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	263	2	,	,	,
cord-347298-7kqrl3rv	263	3	the	the	DT
cord-347298-7kqrl3rv	263	4	extremely	extremely	RB
cord-347298-7kqrl3rv	263	5	variable	variable	JJ
cord-347298-7kqrl3rv	263	6	level	level	NN
cord-347298-7kqrl3rv	263	7	of	of	IN
cord-347298-7kqrl3rv	263	8	success	success	NN
cord-347298-7kqrl3rv	263	9	of	of	IN
cord-347298-7kqrl3rv	263	10	experiments	experiment	NNS
cord-347298-7kqrl3rv	263	11	by	by	IN
cord-347298-7kqrl3rv	263	12	different	different	JJ
cord-347298-7kqrl3rv	263	13	groups	group	NNS
cord-347298-7kqrl3rv	263	14	using	use	VBG
cord-347298-7kqrl3rv	263	15	different	different	JJ
cord-347298-7kqrl3rv	263	16	transplant	transplant	NN
cord-347298-7kqrl3rv	263	17	models	model	NNS
cord-347298-7kqrl3rv	263	18	has	have	VBZ
cord-347298-7kqrl3rv	263	19	shown	show	VBN
cord-347298-7kqrl3rv	263	20	that	that	IN
cord-347298-7kqrl3rv	263	21	immune	immune	JJ
cord-347298-7kqrl3rv	263	22	privilege	privilege	NN
cord-347298-7kqrl3rv	263	23	of	of	IN
cord-347298-7kqrl3rv	263	24	the	the	DT
cord-347298-7kqrl3rv	263	25	testis	testis	NN
cord-347298-7kqrl3rv	263	26	is	be	VBZ
cord-347298-7kqrl3rv	263	27	both	both	DT
cord-347298-7kqrl3rv	263	28	limited	limited	JJ
cord-347298-7kqrl3rv	263	29	and	and	CC
cord-347298-7kqrl3rv	263	30	conditional	conditional	JJ
cord-347298-7kqrl3rv	263	31	(	(	-LRB-
cord-347298-7kqrl3rv	263	32	Dobrinski	Dobrinski	NNP
cord-347298-7kqrl3rv	263	33	2005	2005	CD
cord-347298-7kqrl3rv	263	34	;	;	:
cord-347298-7kqrl3rv	263	35	Head	Head	NNP
cord-347298-7kqrl3rv	263	36	et	et	NNP
cord-347298-7kqrl3rv	263	37	al	al	NNP
cord-347298-7kqrl3rv	263	38	.	.	NNP
cord-347298-7kqrl3rv	263	39	1983a	1983a	CD
cord-347298-7kqrl3rv	263	40	;	;	:
cord-347298-7kqrl3rv	263	41	Maddocks	Maddocks	NNPS
cord-347298-7kqrl3rv	263	42	and	and	CC
cord-347298-7kqrl3rv	263	43	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	263	44	1988	1988	CD
cord-347298-7kqrl3rv	263	45	;	;	:
cord-347298-7kqrl3rv	264	1	Selawry	Selawry	NNP
cord-347298-7kqrl3rv	264	2	and	and	CC
cord-347298-7kqrl3rv	264	3	Whittington	Whittington	NNP
cord-347298-7kqrl3rv	264	4	1984	1984	CD
cord-347298-7kqrl3rv	264	5	;	;	:
cord-347298-7kqrl3rv	264	6	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	264	7	et	et	FW
cord-347298-7kqrl3rv	264	8	al	al	NNP
cord-347298-7kqrl3rv	264	9	.	.	NNP
cord-347298-7kqrl3rv	264	10	1995	1995	CD
cord-347298-7kqrl3rv	264	11	)	)	-RRB-
cord-347298-7kqrl3rv	264	12	.	.	.
cord-347298-7kqrl3rv	265	1	Just	just	RB
cord-347298-7kqrl3rv	265	2	what	what	WP
cord-347298-7kqrl3rv	265	3	are	be	VBP
cord-347298-7kqrl3rv	265	4	these	these	DT
cord-347298-7kqrl3rv	265	5	necessary	necessary	JJ
cord-347298-7kqrl3rv	265	6	conditions	condition	NNS
cord-347298-7kqrl3rv	265	7	,	,	,
cord-347298-7kqrl3rv	265	8	however	however	RB
cord-347298-7kqrl3rv	265	9	,	,	,
cord-347298-7kqrl3rv	265	10	remains	remain	VBZ
cord-347298-7kqrl3rv	265	11	poorly	poorly	RB
cord-347298-7kqrl3rv	265	12	defined	define	VBN
cord-347298-7kqrl3rv	265	13	.	.	.
cord-347298-7kqrl3rv	266	1	Studies	study	NNS
cord-347298-7kqrl3rv	266	2	indicate	indicate	VBP
cord-347298-7kqrl3rv	266	3	that	that	IN
cord-347298-7kqrl3rv	266	4	the	the	DT
cord-347298-7kqrl3rv	266	5	effector	effector	JJ
cord-347298-7kqrl3rv	266	6	arm	arm	NN
cord-347298-7kqrl3rv	266	7	of	of	IN
cord-347298-7kqrl3rv	266	8	the	the	DT
cord-347298-7kqrl3rv	266	9	immune	immune	JJ
cord-347298-7kqrl3rv	266	10	response	response	NN
cord-347298-7kqrl3rv	266	11	is	be	VBZ
cord-347298-7kqrl3rv	266	12	intact	intact	JJ
cord-347298-7kqrl3rv	266	13	within	within	IN
cord-347298-7kqrl3rv	266	14	the	the	DT
cord-347298-7kqrl3rv	266	15	testis	testis	NN
cord-347298-7kqrl3rv	266	16	,	,	,
cord-347298-7kqrl3rv	266	17	and	and	CC
cord-347298-7kqrl3rv	266	18	it	-PRON-	PRP
cord-347298-7kqrl3rv	266	19	is	be	VBZ
cord-347298-7kqrl3rv	266	20	the	the	DT
cord-347298-7kqrl3rv	266	21	ability	ability	NN
cord-347298-7kqrl3rv	266	22	to	to	TO
cord-347298-7kqrl3rv	266	23	recognize	recognize	VB
cord-347298-7kqrl3rv	266	24	and	and	CC
cord-347298-7kqrl3rv	266	25	react	react	VB
cord-347298-7kqrl3rv	266	26	toward	toward	IN
cord-347298-7kqrl3rv	266	27	foreign	foreign	JJ
cord-347298-7kqrl3rv	266	28	antigens	antigen	NNS
cord-347298-7kqrl3rv	266	29	and/or	and/or	CC
cord-347298-7kqrl3rv	266	30	mount	mount	VB
cord-347298-7kqrl3rv	266	31	a	a	DT
cord-347298-7kqrl3rv	266	32	normal	normal	JJ
cord-347298-7kqrl3rv	266	33	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	266	34	response	response	NN
cord-347298-7kqrl3rv	266	35	that	that	WDT
cord-347298-7kqrl3rv	266	36	is	be	VBZ
cord-347298-7kqrl3rv	266	37	suppressed	suppress	VBN
cord-347298-7kqrl3rv	266	38	(	(	-LRB-
cord-347298-7kqrl3rv	266	39	Head	Head	NNP
cord-347298-7kqrl3rv	266	40	and	and	CC
cord-347298-7kqrl3rv	266	41	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	266	42	1985	1985	CD
cord-347298-7kqrl3rv	266	43	;	;	:
cord-347298-7kqrl3rv	266	44	Head	Head	NNP
cord-347298-7kqrl3rv	266	45	et	et	NNP
cord-347298-7kqrl3rv	266	46	al	al	NNP
cord-347298-7kqrl3rv	266	47	.	.	.
cord-347298-7kqrl3rv	267	1	1983a	1983a	CD
cord-347298-7kqrl3rv	267	2	;	;	:
cord-347298-7kqrl3rv	267	3	Mahi	Mahi	NNP
cord-347298-7kqrl3rv	267	4	-	-	HYPH
cord-347298-7kqrl3rv	267	5	Brown	Brown	NNP
cord-347298-7kqrl3rv	267	6	and	and	CC
cord-347298-7kqrl3rv	267	7	Tung	Tung	NNP
cord-347298-7kqrl3rv	267	8	1989	1989	CD
cord-347298-7kqrl3rv	268	1	;	;	:
cord-347298-7kqrl3rv	268	2	Mahi	Mahi	NNP
cord-347298-7kqrl3rv	268	3	-	-	HYPH
cord-347298-7kqrl3rv	268	4	Brown	Brown	NNP
cord-347298-7kqrl3rv	268	5	et	et	NNP
cord-347298-7kqrl3rv	268	6	al	al	NNP
cord-347298-7kqrl3rv	268	7	.	.	NNP
cord-347298-7kqrl3rv	268	8	1987	1987	CD
cord-347298-7kqrl3rv	268	9	)	)	-RRB-
cord-347298-7kqrl3rv	268	10	.	.	.
cord-347298-7kqrl3rv	269	1	In	in	IN
cord-347298-7kqrl3rv	269	2	summary	summary	NN
cord-347298-7kqrl3rv	269	3	,	,	,
cord-347298-7kqrl3rv	269	4	there	there	EX
cord-347298-7kqrl3rv	269	5	appears	appear	VBZ
cord-347298-7kqrl3rv	269	6	to	to	TO
cord-347298-7kqrl3rv	269	7	be	be	VB
cord-347298-7kqrl3rv	269	8	a	a	DT
cord-347298-7kqrl3rv	269	9	potentially	potentially	RB
cord-347298-7kqrl3rv	269	10	unique	unique	JJ
cord-347298-7kqrl3rv	269	11	functional	functional	JJ
cord-347298-7kqrl3rv	269	12	interaction	interaction	NN
cord-347298-7kqrl3rv	269	13	between	between	IN
cord-347298-7kqrl3rv	269	14	the	the	DT
cord-347298-7kqrl3rv	269	15	testis	testis	NN
cord-347298-7kqrl3rv	269	16	and	and	CC
cord-347298-7kqrl3rv	269	17	the	the	DT
cord-347298-7kqrl3rv	269	18	immune	immune	JJ
cord-347298-7kqrl3rv	269	19	system	system	NN
cord-347298-7kqrl3rv	269	20	,	,	,
cord-347298-7kqrl3rv	269	21	which	which	WDT
cord-347298-7kqrl3rv	269	22	involves	involve	VBZ
cord-347298-7kqrl3rv	269	23	control	control	NN
cord-347298-7kqrl3rv	269	24	of	of	IN
cord-347298-7kqrl3rv	269	25	the	the	DT
cord-347298-7kqrl3rv	269	26	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	269	27	normally	normally	RB
cord-347298-7kqrl3rv	269	28	involved	involve	VBN
cord-347298-7kqrl3rv	269	29	in	in	IN
cord-347298-7kqrl3rv	269	30	immune	immune	JJ
cord-347298-7kqrl3rv	269	31	activation	activation	NN
cord-347298-7kqrl3rv	269	32	,	,	,
cord-347298-7kqrl3rv	269	33	in	in	IN
cord-347298-7kqrl3rv	269	34	order	order	NN
cord-347298-7kqrl3rv	269	35	to	to	TO
cord-347298-7kqrl3rv	269	36	limit	limit	VB
cord-347298-7kqrl3rv	269	37	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	269	38	immune	immune	JJ
cord-347298-7kqrl3rv	269	39	responses	response	NNS
cord-347298-7kqrl3rv	269	40	without	without	IN
cord-347298-7kqrl3rv	269	41	drastically	drastically	RB
cord-347298-7kqrl3rv	269	42	compromising	compromise	VBG
cord-347298-7kqrl3rv	269	43	the	the	DT
cord-347298-7kqrl3rv	269	44	ability	ability	NN
cord-347298-7kqrl3rv	269	45	of	of	IN
cord-347298-7kqrl3rv	269	46	the	the	DT
cord-347298-7kqrl3rv	269	47	testis	testis	NN
cord-347298-7kqrl3rv	269	48	to	to	TO
cord-347298-7kqrl3rv	269	49	protect	protect	VB
cord-347298-7kqrl3rv	269	50	itself	-PRON-	PRP
cord-347298-7kqrl3rv	269	51	when	when	WRB
cord-347298-7kqrl3rv	269	52	required	require	VBN
cord-347298-7kqrl3rv	269	53	.	.	.
cord-347298-7kqrl3rv	270	1	Although	although	IN
cord-347298-7kqrl3rv	270	2	their	-PRON-	PRP$
cord-347298-7kqrl3rv	270	3	presence	presence	NN
cord-347298-7kqrl3rv	270	4	and	and	CC
cord-347298-7kqrl3rv	270	5	influence	influence	NN
cord-347298-7kqrl3rv	270	6	is	be	VBZ
cord-347298-7kqrl3rv	270	7	almost	almost	RB
cord-347298-7kqrl3rv	270	8	universally	universally	RB
cord-347298-7kqrl3rv	270	9	neglected	neglect	VBN
cord-347298-7kqrl3rv	270	10	,	,	,
cord-347298-7kqrl3rv	270	11	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	270	12	,	,	,
cord-347298-7kqrl3rv	270	13	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	270	14	,	,	,
cord-347298-7kqrl3rv	270	15	and	and	CC
cord-347298-7kqrl3rv	270	16	PMNs	pmn	NNS
cord-347298-7kqrl3rv	270	17	have	have	VBP
cord-347298-7kqrl3rv	270	18	varying	vary	VBG
cord-347298-7kqrl3rv	270	19	degrees	degree	NNS
cord-347298-7kqrl3rv	270	20	of	of	IN
cord-347298-7kqrl3rv	270	21	access	access	NN
cord-347298-7kqrl3rv	270	22	to	to	IN
cord-347298-7kqrl3rv	270	23	the	the	DT
cord-347298-7kqrl3rv	270	24	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	270	25	tissue	tissue	NN
cord-347298-7kqrl3rv	270	26	of	of	IN
cord-347298-7kqrl3rv	270	27	the	the	DT
cord-347298-7kqrl3rv	270	28	testis	testis	NN
cord-347298-7kqrl3rv	270	29	(	(	-LRB-
cord-347298-7kqrl3rv	270	30	Table	table	NN
cord-347298-7kqrl3rv	270	31	1	1	CD
cord-347298-7kqrl3rv	270	32	)	)	-RRB-
cord-347298-7kqrl3rv	270	33	.	.	.
cord-347298-7kqrl3rv	271	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	271	2	are	be	VBP
cord-347298-7kqrl3rv	271	3	generally	generally	RB
cord-347298-7kqrl3rv	271	4	excluded	exclude	VBN
cord-347298-7kqrl3rv	271	5	from	from	IN
cord-347298-7kqrl3rv	271	6	the	the	DT
cord-347298-7kqrl3rv	271	7	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	271	8	epithelium	epithelium	NN
cord-347298-7kqrl3rv	271	9	under	under	IN
cord-347298-7kqrl3rv	271	10	normal	normal	JJ
cord-347298-7kqrl3rv	271	11	conditions	condition	NNS
cord-347298-7kqrl3rv	271	12	.	.	.
cord-347298-7kqrl3rv	272	1	Over	over	IN
cord-347298-7kqrl3rv	272	2	the	the	DT
cord-347298-7kqrl3rv	272	3	past	past	JJ
cord-347298-7kqrl3rv	272	4	10	10	CD
cord-347298-7kqrl3rv	272	5	years	year	NNS
cord-347298-7kqrl3rv	272	6	,	,	,
cord-347298-7kqrl3rv	272	7	studies	study	NNS
cord-347298-7kqrl3rv	272	8	have	have	VBP
cord-347298-7kqrl3rv	272	9	started	start	VBN
cord-347298-7kqrl3rv	272	10	to	to	TO
cord-347298-7kqrl3rv	272	11	fill	fill	VB
cord-347298-7kqrl3rv	272	12	in	in	RP
cord-347298-7kqrl3rv	272	13	some	some	DT
cord-347298-7kqrl3rv	272	14	of	of	IN
cord-347298-7kqrl3rv	272	15	the	the	DT
cord-347298-7kqrl3rv	272	16	details	detail	NNS
cord-347298-7kqrl3rv	272	17	concerning	concern	VBG
cord-347298-7kqrl3rv	272	18	these	these	DT
cord-347298-7kqrl3rv	272	19	cells	cell	NNS
cord-347298-7kqrl3rv	272	20	.	.	.
cord-347298-7kqrl3rv	273	1	Macrophages	macrophage	NNS
cord-347298-7kqrl3rv	273	2	are	be	VBP
cord-347298-7kqrl3rv	273	3	by	by	IN
cord-347298-7kqrl3rv	273	4	far	far	RB
cord-347298-7kqrl3rv	273	5	the	the	DT
cord-347298-7kqrl3rv	273	6	most	most	RBS
cord-347298-7kqrl3rv	273	7	prominent	prominent	JJ
cord-347298-7kqrl3rv	273	8	immune	immune	JJ
cord-347298-7kqrl3rv	273	9	cells	cell	NNS
cord-347298-7kqrl3rv	273	10	in	in	IN
cord-347298-7kqrl3rv	273	11	the	the	DT
cord-347298-7kqrl3rv	273	12	testis	testis	NN
cord-347298-7kqrl3rv	273	13	.	.	.
cord-347298-7kqrl3rv	274	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	274	2	are	be	VBP
cord-347298-7kqrl3rv	274	3	found	find	VBN
cord-347298-7kqrl3rv	274	4	in	in	IN
cord-347298-7kqrl3rv	274	5	the	the	DT
cord-347298-7kqrl3rv	274	6	testes	testis	NNS
cord-347298-7kqrl3rv	274	7	of	of	IN
cord-347298-7kqrl3rv	274	8	all	all	DT
cord-347298-7kqrl3rv	274	9	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	274	10	species	specie	NNS
cord-347298-7kqrl3rv	274	11	so	so	RB
cord-347298-7kqrl3rv	274	12	far	far	RB
cord-347298-7kqrl3rv	274	13	examined	examine	VBN
cord-347298-7kqrl3rv	274	14	,	,	,
cord-347298-7kqrl3rv	274	15	but	but	CC
cord-347298-7kqrl3rv	274	16	are	be	VBP
cord-347298-7kqrl3rv	274	17	particularly	particularly	RB
cord-347298-7kqrl3rv	274	18	numerous	numerous	JJ
cord-347298-7kqrl3rv	274	19	in	in	IN
cord-347298-7kqrl3rv	274	20	human	human	NN
cord-347298-7kqrl3rv	274	21	,	,	,
cord-347298-7kqrl3rv	274	22	rat	rat	NN
cord-347298-7kqrl3rv	274	23	,	,	,
cord-347298-7kqrl3rv	274	24	and	and	CC
cord-347298-7kqrl3rv	274	25	mouse	mouse	NN
cord-347298-7kqrl3rv	274	26	testes	testis	NNS
cord-347298-7kqrl3rv	274	27	(	(	-LRB-
cord-347298-7kqrl3rv	274	28	Frungieri	Frungieri	NNP
cord-347298-7kqrl3rv	274	29	et	et	FW
cord-347298-7kqrl3rv	274	30	al	al	NNP
cord-347298-7kqrl3rv	274	31	.	.	.
cord-347298-7kqrl3rv	274	32	2002	2002	CD
cord-347298-7kqrl3rv	274	33	;	;	:
cord-347298-7kqrl3rv	274	34	Hume	Hume	NNP
cord-347298-7kqrl3rv	274	35	et	et	NNP
cord-347298-7kqrl3rv	274	36	al	al	NNP
cord-347298-7kqrl3rv	274	37	.	.	.
cord-347298-7kqrl3rv	274	38	1984	1984	CD
cord-347298-7kqrl3rv	274	39	;	;	:
cord-347298-7kqrl3rv	274	40	Mendis	Mendis	NNP
cord-347298-7kqrl3rv	274	41	-	-	HYPH
cord-347298-7kqrl3rv	274	42	Handagama	Handagama	NNP
cord-347298-7kqrl3rv	274	43	et	et	NNP
cord-347298-7kqrl3rv	274	44	al	al	NNP
cord-347298-7kqrl3rv	274	45	.	.	NNP
cord-347298-7kqrl3rv	274	46	1987	1987	CD
cord-347298-7kqrl3rv	274	47	;	;	:
cord-347298-7kqrl3rv	274	48	Miller	Miller	NNP
cord-347298-7kqrl3rv	274	49	et	et	NNP
cord-347298-7kqrl3rv	274	50	al	al	NNP
cord-347298-7kqrl3rv	274	51	.	.	.
cord-347298-7kqrl3rv	274	52	1984	1984	CD
cord-347298-7kqrl3rv	274	53	;	;	:
cord-347298-7kqrl3rv	274	54	Vergouwen	Vergouwen	NNP
cord-347298-7kqrl3rv	274	55	et	et	NNP
cord-347298-7kqrl3rv	274	56	al	al	NNP
cord-347298-7kqrl3rv	274	57	.	.	NNP
cord-347298-7kqrl3rv	274	58	1993	1993	CD
cord-347298-7kqrl3rv	274	59	;	;	:
cord-347298-7kqrl3rv	274	60	Wang	Wang	NNP
cord-347298-7kqrl3rv	274	61	et	et	NNP
cord-347298-7kqrl3rv	274	62	al	al	NNP
cord-347298-7kqrl3rv	274	63	.	.	.
cord-347298-7kqrl3rv	274	64	1994	1994	CD
cord-347298-7kqrl3rv	274	65	)	)	-RRB-
cord-347298-7kqrl3rv	274	66	.	.	.
cord-347298-7kqrl3rv	275	1	Typically	typically	RB
cord-347298-7kqrl3rv	275	2	,	,	,
cord-347298-7kqrl3rv	275	3	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	275	4	arise	arise	VBP
cord-347298-7kqrl3rv	275	5	from	from	IN
cord-347298-7kqrl3rv	275	6	myeloid	myeloid	JJ
cord-347298-7kqrl3rv	275	7	precursors	precursor	NNS
cord-347298-7kqrl3rv	275	8	in	in	IN
cord-347298-7kqrl3rv	275	9	the	the	DT
cord-347298-7kqrl3rv	275	10	bone	bone	NN
cord-347298-7kqrl3rv	275	11	marrow	marrow	NN
cord-347298-7kqrl3rv	275	12	and	and	CC
cord-347298-7kqrl3rv	275	13	circulate	circulate	VB
cord-347298-7kqrl3rv	275	14	in	in	IN
cord-347298-7kqrl3rv	275	15	the	the	DT
cord-347298-7kqrl3rv	275	16	blood	blood	NN
cord-347298-7kqrl3rv	275	17	as	as	IN
cord-347298-7kqrl3rv	275	18	monocytes	monocyte	NNS
cord-347298-7kqrl3rv	275	19	.	.	.
cord-347298-7kqrl3rv	276	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	276	2	are	be	VBP
cord-347298-7kqrl3rv	276	3	capable	capable	JJ
cord-347298-7kqrl3rv	276	4	of	of	IN
cord-347298-7kqrl3rv	276	5	adopting	adopt	VBG
cord-347298-7kqrl3rv	276	6	a	a	DT
cord-347298-7kqrl3rv	276	7	broad	broad	JJ
cord-347298-7kqrl3rv	276	8	range	range	NN
cord-347298-7kqrl3rv	276	9	of	of	IN
cord-347298-7kqrl3rv	276	10	structural	structural	JJ
cord-347298-7kqrl3rv	276	11	and	and	CC
cord-347298-7kqrl3rv	276	12	functional	functional	JJ
cord-347298-7kqrl3rv	276	13	phenotypes	phenotype	NNS
cord-347298-7kqrl3rv	276	14	that	that	WDT
cord-347298-7kqrl3rv	276	15	are	be	VBP
cord-347298-7kqrl3rv	276	16	largely	largely	RB
cord-347298-7kqrl3rv	276	17	dictated	dictate	VBN
cord-347298-7kqrl3rv	276	18	by	by	IN
cord-347298-7kqrl3rv	276	19	the	the	DT
cord-347298-7kqrl3rv	276	20	tissues	tissue	NNS
cord-347298-7kqrl3rv	276	21	in	in	IN
cord-347298-7kqrl3rv	276	22	which	which	WDT
cord-347298-7kqrl3rv	276	23	they	-PRON-	PRP
cord-347298-7kqrl3rv	276	24	become	become	VBP
cord-347298-7kqrl3rv	276	25	resident	resident	JJ
cord-347298-7kqrl3rv	277	1	(	(	-LRB-
cord-347298-7kqrl3rv	277	2	Mantovani	Mantovani	NNP
cord-347298-7kqrl3rv	277	3	et	et	NNP
cord-347298-7kqrl3rv	277	4	al	al	NNP
cord-347298-7kqrl3rv	277	5	.	.	.
cord-347298-7kqrl3rv	278	1	2005	2005	CD
cord-347298-7kqrl3rv	278	2	;	;	:
cord-347298-7kqrl3rv	278	3	van	van	NNP
cord-347298-7kqrl3rv	278	4	Furth	Furth	NNP
cord-347298-7kqrl3rv	278	5	1988	1988	CD
cord-347298-7kqrl3rv	278	6	)	)	-RRB-
cord-347298-7kqrl3rv	278	7	.	.	.
cord-347298-7kqrl3rv	279	1	Characteristically	characteristically	RB
cord-347298-7kqrl3rv	279	2	,	,	,
cord-347298-7kqrl3rv	279	3	they	-PRON-	PRP
cord-347298-7kqrl3rv	279	4	are	be	VBP
cord-347298-7kqrl3rv	279	5	robustly	robustly	RB
cord-347298-7kqrl3rv	279	6	phagocytic	phagocytic	JJ
cord-347298-7kqrl3rv	279	7	and	and	CC
cord-347298-7kqrl3rv	279	8	possess	possess	VBP
cord-347298-7kqrl3rv	279	9	a	a	DT
cord-347298-7kqrl3rv	279	10	potent	potent	JJ
cord-347298-7kqrl3rv	279	11	arsenal	arsenal	NN
cord-347298-7kqrl3rv	279	12	of	of	IN
cord-347298-7kqrl3rv	279	13	antimicrobial	antimicrobial	JJ
cord-347298-7kqrl3rv	279	14	and	and	CC
cord-347298-7kqrl3rv	279	15	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	279	16	activities	activity	NNS
cord-347298-7kqrl3rv	279	17	,	,	,
cord-347298-7kqrl3rv	279	18	such	such	JJ
cord-347298-7kqrl3rv	279	19	as	as	IN
cord-347298-7kqrl3rv	279	20	the	the	DT
cord-347298-7kqrl3rv	279	21	ability	ability	NN
cord-347298-7kqrl3rv	279	22	to	to	TO
cord-347298-7kqrl3rv	279	23	generate	generate	VB
cord-347298-7kqrl3rv	279	24	large	large	JJ
cord-347298-7kqrl3rv	279	25	amounts	amount	NNS
cord-347298-7kqrl3rv	279	26	of	of	IN
cord-347298-7kqrl3rv	279	27	ROS	ROS	NNP
cord-347298-7kqrl3rv	279	28	.	.	.
cord-347298-7kqrl3rv	280	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	280	2	produce	produce	VBP
cord-347298-7kqrl3rv	280	3	many	many	JJ
cord-347298-7kqrl3rv	280	4	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	280	5	products	product	NNS
cord-347298-7kqrl3rv	280	6	,	,	,
cord-347298-7kqrl3rv	280	7	including	include	VBG
cord-347298-7kqrl3rv	280	8	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	280	9	,	,	,
cord-347298-7kqrl3rv	280	10	eicosanoids	eicosanoid	NNS
cord-347298-7kqrl3rv	280	11	(	(	-LRB-
cord-347298-7kqrl3rv	280	12	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	280	13	,	,	,
cord-347298-7kqrl3rv	280	14	thromboxanes	thromboxane	NNS
cord-347298-7kqrl3rv	280	15	,	,	,
cord-347298-7kqrl3rv	280	16	leukotrienes	leukotriene	NNS
cord-347298-7kqrl3rv	280	17	,	,	,
cord-347298-7kqrl3rv	280	18	and	and	CC
cord-347298-7kqrl3rv	280	19	lipoxins	lipoxins	NNP
cord-347298-7kqrl3rv	280	20	)	)	-RRB-
cord-347298-7kqrl3rv	280	21	,	,	,
cord-347298-7kqrl3rv	280	22	and	and	CC
cord-347298-7kqrl3rv	280	23	nitric	nitric	NN
cord-347298-7kqrl3rv	280	24	oxide	oxide	NN
cord-347298-7kqrl3rv	280	25	,	,	,
cord-347298-7kqrl3rv	280	26	all	all	DT
cord-347298-7kqrl3rv	280	27	of	of	IN
cord-347298-7kqrl3rv	280	28	which	which	WDT
cord-347298-7kqrl3rv	280	29	are	be	VBP
cord-347298-7kqrl3rv	280	30	important	important	JJ
cord-347298-7kqrl3rv	280	31	in	in	IN
cord-347298-7kqrl3rv	280	32	establishing	establish	VBG
cord-347298-7kqrl3rv	280	33	and	and	CC
cord-347298-7kqrl3rv	280	34	controlling	control	VBG
cord-347298-7kqrl3rv	280	35	the	the	DT
cord-347298-7kqrl3rv	280	36	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	280	37	process	process	NN
cord-347298-7kqrl3rv	280	38	,	,	,
cord-347298-7kqrl3rv	280	39	but	but	CC
cord-347298-7kqrl3rv	280	40	also	also	RB
cord-347298-7kqrl3rv	280	41	have	have	VB
cord-347298-7kqrl3rv	280	42	important	important	JJ
cord-347298-7kqrl3rv	280	43	roles	role	NNS
cord-347298-7kqrl3rv	280	44	in	in	IN
cord-347298-7kqrl3rv	280	45	tissue	tissue	NN
cord-347298-7kqrl3rv	280	46	remodeling	remodeling	NN
cord-347298-7kqrl3rv	280	47	,	,	,
cord-347298-7kqrl3rv	280	48	healing	healing	NN
cord-347298-7kqrl3rv	280	49	,	,	,
cord-347298-7kqrl3rv	280	50	and	and	CC
cord-347298-7kqrl3rv	280	51	normal	normal	JJ
cord-347298-7kqrl3rv	280	52	homeostasis	homeostasis	NN
cord-347298-7kqrl3rv	280	53	.	.	.
cord-347298-7kqrl3rv	281	1	All	all	DT
cord-347298-7kqrl3rv	281	2	macrophage	macrophage	NN
cord-347298-7kqrl3rv	281	3	lineages	lineage	NNS
cord-347298-7kqrl3rv	281	4	can	can	MD
cord-347298-7kqrl3rv	281	5	express	express	VB
cord-347298-7kqrl3rv	281	6	MHC	MHC	NNP
cord-347298-7kqrl3rv	281	7	class	class	NN
cord-347298-7kqrl3rv	281	8	II	II	NNP
cord-347298-7kqrl3rv	281	9	antigens	antigen	NNS
cord-347298-7kqrl3rv	281	10	and	and	CC
cord-347298-7kqrl3rv	281	11	have	have	VBP
cord-347298-7kqrl3rv	281	12	the	the	DT
cord-347298-7kqrl3rv	281	13	capacity	capacity	NN
cord-347298-7kqrl3rv	281	14	to	to	TO
cord-347298-7kqrl3rv	281	15	present	present	VB
cord-347298-7kqrl3rv	281	16	to	to	IN
cord-347298-7kqrl3rv	281	17	CD4	CD4	NNP
cord-347298-7kqrl3rv	281	18	þ	þ	NNP
cord-347298-7kqrl3rv	281	19	helper	helper	NN
cord-347298-7kqrl3rv	281	20	or	or	CC
cord-347298-7kqrl3rv	281	21	T	T	NNP
cord-347298-7kqrl3rv	281	22	reg	reg	NN
cord-347298-7kqrl3rv	281	23	cells	cell	NNS
cord-347298-7kqrl3rv	281	24	(	(	-LRB-
cord-347298-7kqrl3rv	281	25	Unanue	Unanue	NNP
cord-347298-7kqrl3rv	281	26	1984	1984	CD
cord-347298-7kqrl3rv	281	27	)	)	-RRB-
cord-347298-7kqrl3rv	281	28	.	.	.
cord-347298-7kqrl3rv	282	1	Thus	thus	RB
cord-347298-7kqrl3rv	282	2	,	,	,
cord-347298-7kqrl3rv	282	3	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	282	4	are	be	VBP
cord-347298-7kqrl3rv	282	5	the	the	DT
cord-347298-7kqrl3rv	282	6	cells	cell	NNS
cord-347298-7kqrl3rv	282	7	that	that	WDT
cord-347298-7kqrl3rv	282	8	link	link	VBP
cord-347298-7kqrl3rv	282	9	innate	innate	JJ
cord-347298-7kqrl3rv	282	10	and	and	CC
cord-347298-7kqrl3rv	282	11	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	282	12	immunity	immunity	NN
cord-347298-7kqrl3rv	282	13	,	,	,
cord-347298-7kqrl3rv	282	14	and	and	CC
cord-347298-7kqrl3rv	282	15	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	282	16	cells	cell	NNS
cord-347298-7kqrl3rv	282	17	are	be	VBP
cord-347298-7kqrl3rv	282	18	a	a	DT
cord-347298-7kqrl3rv	282	19	highly	highly	RB
cord-347298-7kqrl3rv	282	20	specialized	specialized	JJ
cord-347298-7kqrl3rv	282	21	macrophage	macrophage	NN
cord-347298-7kqrl3rv	282	22	subset	subset	NN
cord-347298-7kqrl3rv	282	23	that	that	WDT
cord-347298-7kqrl3rv	282	24	is	be	VBZ
cord-347298-7kqrl3rv	282	25	particularly	particularly	RB
cord-347298-7kqrl3rv	282	26	effective	effective	JJ
cord-347298-7kqrl3rv	282	27	in	in	IN
cord-347298-7kqrl3rv	282	28	this	this	DT
cord-347298-7kqrl3rv	282	29	role	role	NN
cord-347298-7kqrl3rv	282	30	(	(	-LRB-
cord-347298-7kqrl3rv	282	31	Heath	Heath	NNP
cord-347298-7kqrl3rv	282	32	and	and	CC
cord-347298-7kqrl3rv	282	33	Carbone	Carbone	NNP
cord-347298-7kqrl3rv	282	34	2001	2001	CD
cord-347298-7kqrl3rv	282	35	)	)	-RRB-
cord-347298-7kqrl3rv	282	36	.	.	.
cord-347298-7kqrl3rv	283	1	Testicular	testicular	JJ
cord-347298-7kqrl3rv	283	2	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	283	3	have	have	VBP
cord-347298-7kqrl3rv	283	4	been	be	VBN
cord-347298-7kqrl3rv	283	5	most	most	RBS
cord-347298-7kqrl3rv	283	6	extensively	extensively	RB
cord-347298-7kqrl3rv	283	7	studied	study	VBN
cord-347298-7kqrl3rv	283	8	in	in	IN
cord-347298-7kqrl3rv	283	9	the	the	DT
cord-347298-7kqrl3rv	283	10	rat	rat	NN
cord-347298-7kqrl3rv	283	11	,	,	,
cord-347298-7kqrl3rv	283	12	with	with	IN
cord-347298-7kqrl3rv	283	13	a	a	DT
cord-347298-7kqrl3rv	283	14	few	few	JJ
cord-347298-7kqrl3rv	283	15	studies	study	NNS
cord-347298-7kqrl3rv	283	16	also	also	RB
cord-347298-7kqrl3rv	283	17	in	in	IN
cord-347298-7kqrl3rv	283	18	the	the	DT
cord-347298-7kqrl3rv	283	19	mouse	mouse	NN
cord-347298-7kqrl3rv	283	20	and	and	CC
cord-347298-7kqrl3rv	283	21	human	human	NN
cord-347298-7kqrl3rv	283	22	.	.	.
cord-347298-7kqrl3rv	284	1	Studies	study	NNS
cord-347298-7kqrl3rv	284	2	in	in	IN
cord-347298-7kqrl3rv	284	3	the	the	DT
cord-347298-7kqrl3rv	284	4	rat	rat	NN
cord-347298-7kqrl3rv	284	5	indicate	indicate	VBP
cord-347298-7kqrl3rv	284	6	that	that	IN
cord-347298-7kqrl3rv	284	7	they	-PRON-	PRP
cord-347298-7kqrl3rv	284	8	are	be	VBP
cord-347298-7kqrl3rv	284	9	heterogenous	heterogenous	JJ
cord-347298-7kqrl3rv	284	10	in	in	IN
cord-347298-7kqrl3rv	284	11	their	-PRON-	PRP$
cord-347298-7kqrl3rv	284	12	morphology	morphology	NN
cord-347298-7kqrl3rv	284	13	and	and	CC
cord-347298-7kqrl3rv	284	14	functions	function	NNS
cord-347298-7kqrl3rv	285	1	(	(	-LRB-
cord-347298-7kqrl3rv	285	2	Bryniarski	Bryniarski	NNP
cord-347298-7kqrl3rv	285	3	et	et	NNP
cord-347298-7kqrl3rv	285	4	al	al	NNP
cord-347298-7kqrl3rv	285	5	.	.	.
cord-347298-7kqrl3rv	286	1	2004	2004	CD
cord-347298-7kqrl3rv	286	2	;	;	:
cord-347298-7kqrl3rv	286	3	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	286	4	et	et	NNP
cord-347298-7kqrl3rv	286	5	al	al	NNP
cord-347298-7kqrl3rv	286	6	.	.	.
cord-347298-7kqrl3rv	287	1	2002a	2002a	CD
cord-347298-7kqrl3rv	288	1	;	;	:
cord-347298-7kqrl3rv	288	2	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	288	3	et	et	NNP
cord-347298-7kqrl3rv	288	4	al	al	NNP
cord-347298-7kqrl3rv	288	5	.	.	.
cord-347298-7kqrl3rv	289	1	1995b	1995b	CD
cord-347298-7kqrl3rv	290	1	;	;	:
cord-347298-7kqrl3rv	290	2	Wang	Wang	NNP
cord-347298-7kqrl3rv	290	3	et	et	NNP
cord-347298-7kqrl3rv	290	4	al	al	NNP
cord-347298-7kqrl3rv	290	5	.	.	.
cord-347298-7kqrl3rv	290	6	1994	1994	CD
cord-347298-7kqrl3rv	290	7	)	)	-RRB-
cord-347298-7kqrl3rv	290	8	.	.	.
cord-347298-7kqrl3rv	291	1	Their	-PRON-	PRP$
cord-347298-7kqrl3rv	291	2	absolute	absolute	JJ
cord-347298-7kqrl3rv	291	3	numbers	number	NNS
cord-347298-7kqrl3rv	291	4	are	be	VBP
cord-347298-7kqrl3rv	291	5	primarily	primarily	RB
cord-347298-7kqrl3rv	291	6	under	under	IN
cord-347298-7kqrl3rv	291	7	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	291	8	cell	cell	NN
cord-347298-7kqrl3rv	291	9	control	control	NN
cord-347298-7kqrl3rv	291	10	,	,	,
cord-347298-7kqrl3rv	291	11	but	but	CC
cord-347298-7kqrl3rv	291	12	evidence	evidence	NN
cord-347298-7kqrl3rv	291	13	suggests	suggest	VBZ
cord-347298-7kqrl3rv	291	14	that	that	IN
cord-347298-7kqrl3rv	291	15	FSH	fsh	NN
cord-347298-7kqrl3rv	291	16	acting	act	VBG
cord-347298-7kqrl3rv	291	17	via	via	IN
cord-347298-7kqrl3rv	291	18	the	the	DT
cord-347298-7kqrl3rv	291	19	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	291	20	cell	cell	NN
cord-347298-7kqrl3rv	291	21	has	have	VBZ
cord-347298-7kqrl3rv	291	22	a	a	DT
cord-347298-7kqrl3rv	291	23	role	role	NN
cord-347298-7kqrl3rv	291	24	in	in	IN
cord-347298-7kqrl3rv	291	25	regulating	regulate	VBG
cord-347298-7kqrl3rv	291	26	their	-PRON-	PRP$
cord-347298-7kqrl3rv	291	27	functional	functional	JJ
cord-347298-7kqrl3rv	291	28	activity	activity	NN
cord-347298-7kqrl3rv	291	29	(	(	-LRB-
cord-347298-7kqrl3rv	291	30	Duckett	Duckett	NNP
cord-347298-7kqrl3rv	291	31	et	et	FW
cord-347298-7kqrl3rv	291	32	al	al	NNP
cord-347298-7kqrl3rv	291	33	.	.	.
cord-347298-7kqrl3rv	292	1	1997a	1997a	CD
cord-347298-7kqrl3rv	292	2	,	,	,
cord-347298-7kqrl3rv	292	3	b	b	NN
cord-347298-7kqrl3rv	292	4	;	;	:
cord-347298-7kqrl3rv	292	5	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	292	6	et	et	NNP
cord-347298-7kqrl3rv	292	7	al	al	NNP
cord-347298-7kqrl3rv	292	8	.	.	NNP
cord-347298-7kqrl3rv	292	9	1994c	1994c	CD
cord-347298-7kqrl3rv	292	10	;	;	:
cord-347298-7kqrl3rv	292	11	Wang	Wang	NNP
cord-347298-7kqrl3rv	292	12	et	et	NNP
cord-347298-7kqrl3rv	292	13	al	al	NNP
cord-347298-7kqrl3rv	292	14	.	.	.
cord-347298-7kqrl3rv	292	15	1994	1994	CD
cord-347298-7kqrl3rv	292	16	)	)	-RRB-
cord-347298-7kqrl3rv	292	17	.	.	.
cord-347298-7kqrl3rv	293	1	Macrophages	macrophage	NNS
cord-347298-7kqrl3rv	293	2	accumulate	accumulate	VBP
cord-347298-7kqrl3rv	293	3	within	within	IN
cord-347298-7kqrl3rv	293	4	the	the	DT
cord-347298-7kqrl3rv	293	5	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	293	6	tissue	tissue	NN
cord-347298-7kqrl3rv	293	7	at	at	IN
cord-347298-7kqrl3rv	293	8	the	the	DT
cord-347298-7kqrl3rv	293	9	time	time	NN
cord-347298-7kqrl3rv	293	10	of	of	IN
cord-347298-7kqrl3rv	293	11	puberty	puberty	NN
cord-347298-7kqrl3rv	293	12	,	,	,
cord-347298-7kqrl3rv	293	13	and	and	CC
cord-347298-7kqrl3rv	293	14	play	play	VB
cord-347298-7kqrl3rv	293	15	critical	critical	JJ
cord-347298-7kqrl3rv	293	16	roles	role	NNS
cord-347298-7kqrl3rv	293	17	in	in	IN
cord-347298-7kqrl3rv	293	18	the	the	DT
cord-347298-7kqrl3rv	293	19	normal	normal	JJ
cord-347298-7kqrl3rv	293	20	development	development	NN
cord-347298-7kqrl3rv	293	21	of	of	IN
cord-347298-7kqrl3rv	293	22	the	the	DT
cord-347298-7kqrl3rv	293	23	testis	testis	NN
cord-347298-7kqrl3rv	293	24	,	,	,
cord-347298-7kqrl3rv	293	25	particularly	particularly	RB
cord-347298-7kqrl3rv	293	26	by	by	IN
cord-347298-7kqrl3rv	293	27	promoting	promote	VBG
cord-347298-7kqrl3rv	293	28	the	the	DT
cord-347298-7kqrl3rv	293	29	proliferation	proliferation	NN
cord-347298-7kqrl3rv	293	30	and	and	CC
cord-347298-7kqrl3rv	293	31	maturation	maturation	NN
cord-347298-7kqrl3rv	293	32	of	of	IN
cord-347298-7kqrl3rv	293	33	the	the	DT
cord-347298-7kqrl3rv	293	34	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	293	35	cell	cell	NN
cord-347298-7kqrl3rv	293	36	population	population	NN
cord-347298-7kqrl3rv	293	37	(	(	-LRB-
cord-347298-7kqrl3rv	293	38	Cohen	Cohen	NNP
cord-347298-7kqrl3rv	293	39	et	et	NNP
cord-347298-7kqrl3rv	293	40	al	al	NNP
cord-347298-7kqrl3rv	293	41	.	.	.
cord-347298-7kqrl3rv	293	42	1997	1997	CD
cord-347298-7kqrl3rv	293	43	;	;	:
cord-347298-7kqrl3rv	293	44	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	293	45	et	et	NNP
cord-347298-7kqrl3rv	293	46	al	al	NNP
cord-347298-7kqrl3rv	293	47	.	.	.
cord-347298-7kqrl3rv	294	1	1994a	1994a	CD
cord-347298-7kqrl3rv	294	2	,	,	,
cord-347298-7kqrl3rv	294	3	b	b	LS
cord-347298-7kqrl3rv	294	4	;	;	:
cord-347298-7kqrl3rv	294	5	Hardy	Hardy	NNP
cord-347298-7kqrl3rv	294	6	et	et	NNP
cord-347298-7kqrl3rv	294	7	al	al	NNP
cord-347298-7kqrl3rv	294	8	.	.	NNP
cord-347298-7kqrl3rv	294	9	1989	1989	CD
cord-347298-7kqrl3rv	294	10	;	;	:
cord-347298-7kqrl3rv	295	1	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	295	2	et	et	NNP
cord-347298-7kqrl3rv	295	3	al	al	NNP
cord-347298-7kqrl3rv	295	4	.	.	.
cord-347298-7kqrl3rv	296	1	1999	1999	CD
cord-347298-7kqrl3rv	296	2	;	;	:
cord-347298-7kqrl3rv	296	3	Raburn	Raburn	NNP
cord-347298-7kqrl3rv	296	4	et	et	NNP
cord-347298-7kqrl3rv	296	5	al	al	NNP
cord-347298-7kqrl3rv	296	6	.	.	.
cord-347298-7kqrl3rv	296	7	1993	1993	CD
cord-347298-7kqrl3rv	297	1	;	;	:
cord-347298-7kqrl3rv	297	2	Vergouwen	Vergouwen	NNP
cord-347298-7kqrl3rv	297	3	et	et	NNP
cord-347298-7kqrl3rv	297	4	al	al	NNP
cord-347298-7kqrl3rv	297	5	.	.	.
cord-347298-7kqrl3rv	297	6	1993	1993	CD
cord-347298-7kqrl3rv	297	7	)	)	-RRB-
cord-347298-7kqrl3rv	297	8	.	.	.
cord-347298-7kqrl3rv	298	1	Through	through	IN
cord-347298-7kqrl3rv	298	2	their	-PRON-	PRP$
cord-347298-7kqrl3rv	298	3	ability	ability	NN
cord-347298-7kqrl3rv	298	4	to	to	TO
cord-347298-7kqrl3rv	298	5	produce	produce	VB
cord-347298-7kqrl3rv	298	6	a	a	DT
cord-347298-7kqrl3rv	298	7	broad	broad	JJ
cord-347298-7kqrl3rv	298	8	array	array	NN
cord-347298-7kqrl3rv	298	9	of	of	IN
cord-347298-7kqrl3rv	298	10	growth	growth	NN
cord-347298-7kqrl3rv	298	11	factors	factor	NNS
cord-347298-7kqrl3rv	298	12	,	,	,
cord-347298-7kqrl3rv	298	13	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	298	14	,	,	,
cord-347298-7kqrl3rv	298	15	and	and	CC
cord-347298-7kqrl3rv	298	16	vasoactive	vasoactive	JJ
cord-347298-7kqrl3rv	298	17	regulators	regulator	NNS
cord-347298-7kqrl3rv	298	18	,	,	,
cord-347298-7kqrl3rv	298	19	other	other	JJ
cord-347298-7kqrl3rv	298	20	developmental	developmental	JJ
cord-347298-7kqrl3rv	298	21	and	and	CC
cord-347298-7kqrl3rv	298	22	homeostatic	homeostatic	JJ
cord-347298-7kqrl3rv	298	23	roles	role	NNS
cord-347298-7kqrl3rv	298	24	within	within	IN
cord-347298-7kqrl3rv	298	25	the	the	DT
cord-347298-7kqrl3rv	298	26	testis	testis	NN
cord-347298-7kqrl3rv	298	27	may	may	MD
cord-347298-7kqrl3rv	298	28	be	be	VB
cord-347298-7kqrl3rv	298	29	predicted	predict	VBN
cord-347298-7kqrl3rv	298	30	as	as	RB
cord-347298-7kqrl3rv	298	31	well	well	RB
cord-347298-7kqrl3rv	298	32	.	.	.
cord-347298-7kqrl3rv	299	1	Data	datum	NNS
cord-347298-7kqrl3rv	299	2	concerning	concern	VBG
cord-347298-7kqrl3rv	299	3	the	the	DT
cord-347298-7kqrl3rv	299	4	immunological	immunological	JJ
cord-347298-7kqrl3rv	299	5	functions	function	NNS
cord-347298-7kqrl3rv	299	6	of	of	IN
cord-347298-7kqrl3rv	299	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	299	8	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	299	9	are	be	VBP
cord-347298-7kqrl3rv	299	10	based	base	VBN
cord-347298-7kqrl3rv	299	11	on	on	IN
cord-347298-7kqrl3rv	299	12	a	a	DT
cord-347298-7kqrl3rv	299	13	relatively	relatively	RB
cord-347298-7kqrl3rv	299	14	small	small	JJ
cord-347298-7kqrl3rv	299	15	number	number	NN
cord-347298-7kqrl3rv	299	16	of	of	IN
cord-347298-7kqrl3rv	299	17	studies	study	NNS
cord-347298-7kqrl3rv	299	18	in	in	IN
cord-347298-7kqrl3rv	299	19	either	either	CC
cord-347298-7kqrl3rv	299	20	the	the	DT
cord-347298-7kqrl3rv	299	21	rat	rat	NN
cord-347298-7kqrl3rv	299	22	or	or	CC
cord-347298-7kqrl3rv	299	23	the	the	DT
cord-347298-7kqrl3rv	299	24	mouse	mouse	NN
cord-347298-7kqrl3rv	299	25	,	,	,
cord-347298-7kqrl3rv	299	26	and	and	CC
cord-347298-7kqrl3rv	299	27	are	be	VBP
cord-347298-7kqrl3rv	299	28	patchy	patchy	JJ
cord-347298-7kqrl3rv	299	29	at	at	IN
cord-347298-7kqrl3rv	299	30	best	good	JJS
cord-347298-7kqrl3rv	299	31	.	.	.
cord-347298-7kqrl3rv	300	1	Indeed	indeed	RB
cord-347298-7kqrl3rv	300	2	,	,	,
cord-347298-7kqrl3rv	300	3	there	there	EX
cord-347298-7kqrl3rv	300	4	is	be	VBZ
cord-347298-7kqrl3rv	300	5	some	some	DT
cord-347298-7kqrl3rv	300	6	evidence	evidence	NN
cord-347298-7kqrl3rv	300	7	for	for	IN
cord-347298-7kqrl3rv	300	8	distinct	distinct	JJ
cord-347298-7kqrl3rv	300	9	differences	difference	NNS
cord-347298-7kqrl3rv	300	10	even	even	RB
cord-347298-7kqrl3rv	300	11	between	between	IN
cord-347298-7kqrl3rv	300	12	these	these	DT
cord-347298-7kqrl3rv	300	13	two	two	CD
cord-347298-7kqrl3rv	300	14	closely	closely	RB
cord-347298-7kqrl3rv	300	15	related	relate	VBN
cord-347298-7kqrl3rv	300	16	species	specie	NNS
cord-347298-7kqrl3rv	300	17	.	.	.
cord-347298-7kqrl3rv	301	1	In	in	IN
cord-347298-7kqrl3rv	301	2	general	general	JJ
cord-347298-7kqrl3rv	301	3	,	,	,
cord-347298-7kqrl3rv	301	4	testicular	testicular	JJ
cord-347298-7kqrl3rv	301	5	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	301	6	have	have	VBP
cord-347298-7kqrl3rv	301	7	intact	intact	JJ
cord-347298-7kqrl3rv	301	8	phagocytic	phagocytic	JJ
cord-347298-7kqrl3rv	301	9	,	,	,
cord-347298-7kqrl3rv	301	10	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	301	11	,	,	,
cord-347298-7kqrl3rv	301	12	and	and	CC
cord-347298-7kqrl3rv	301	13	antimicrobial	antimicrobial	JJ
cord-347298-7kqrl3rv	301	14	functions	function	NNS
cord-347298-7kqrl3rv	301	15	(	(	-LRB-
cord-347298-7kqrl3rv	301	16	Miller	Miller	NNP
cord-347298-7kqrl3rv	301	17	et	et	NNP
cord-347298-7kqrl3rv	301	18	al	al	NNP
cord-347298-7kqrl3rv	301	19	.	.	.
cord-347298-7kqrl3rv	301	20	1984	1984	CD
cord-347298-7kqrl3rv	301	21	;	;	:
cord-347298-7kqrl3rv	301	22	Wei	Wei	NNP
cord-347298-7kqrl3rv	301	23	et	et	NNP
cord-347298-7kqrl3rv	301	24	al	al	NNP
cord-347298-7kqrl3rv	301	25	.	.	.
cord-347298-7kqrl3rv	301	26	1988	1988	CD
cord-347298-7kqrl3rv	301	27	)	)	-RRB-
cord-347298-7kqrl3rv	301	28	.	.	.
cord-347298-7kqrl3rv	302	1	Rat	rat	NN
cord-347298-7kqrl3rv	302	2	testis	testis	NN
cord-347298-7kqrl3rv	302	3	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	302	4	express	express	VBP
cord-347298-7kqrl3rv	302	5	MHC	MHC	NNP
cord-347298-7kqrl3rv	302	6	class	class	NN
cord-347298-7kqrl3rv	302	7	II	II	NNP
cord-347298-7kqrl3rv	302	8	antigens	antigen	NNS
cord-347298-7kqrl3rv	302	9	(	(	-LRB-
cord-347298-7kqrl3rv	302	10	Head	Head	NNP
cord-347298-7kqrl3rv	302	11	and	and	CC
cord-347298-7kqrl3rv	302	12	Billingham	Billingham	NNP
cord-347298-7kqrl3rv	302	13	1985	1985	CD
cord-347298-7kqrl3rv	302	14	;	;	:
cord-347298-7kqrl3rv	302	15	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	302	16	and	and	CC
cord-347298-7kqrl3rv	302	17	Eddy	Eddy	NNP
cord-347298-7kqrl3rv	302	18	1987	1987	CD
cord-347298-7kqrl3rv	302	19	;	;	:
cord-347298-7kqrl3rv	302	20	Wang	Wang	NNP
cord-347298-7kqrl3rv	302	21	et	et	NNP
cord-347298-7kqrl3rv	302	22	al	al	NNP
cord-347298-7kqrl3rv	302	23	.	.	.
cord-347298-7kqrl3rv	302	24	1994	1994	CD
cord-347298-7kqrl3rv	302	25	)	)	-RRB-
cord-347298-7kqrl3rv	302	26	,	,	,
cord-347298-7kqrl3rv	302	27	but	but	CC
cord-347298-7kqrl3rv	302	28	display	display	VB
cord-347298-7kqrl3rv	302	29	a	a	DT
cord-347298-7kqrl3rv	302	30	reduced	reduce	VBN
cord-347298-7kqrl3rv	302	31	capacity	capacity	NN
cord-347298-7kqrl3rv	302	32	for	for	IN
cord-347298-7kqrl3rv	302	33	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	302	34	activation	activation	NN
cord-347298-7kqrl3rv	302	35	in	in	IN
cord-347298-7kqrl3rv	302	36	vitro	vitro	FW
cord-347298-7kqrl3rv	302	37	.	.	.
cord-347298-7kqrl3rv	303	1	Testicular	testicular	JJ
cord-347298-7kqrl3rv	303	2	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	303	3	in	in	IN
cord-347298-7kqrl3rv	303	4	the	the	DT
cord-347298-7kqrl3rv	303	5	human	human	NN
cord-347298-7kqrl3rv	303	6	and	and	CC
cord-347298-7kqrl3rv	303	7	mouse	mouse	NN
cord-347298-7kqrl3rv	303	8	also	also	RB
cord-347298-7kqrl3rv	303	9	express	express	VBP
cord-347298-7kqrl3rv	303	10	MHC	MHC	NNP
cord-347298-7kqrl3rv	303	11	class	class	NN
cord-347298-7kqrl3rv	303	12	II	II	NNP
cord-347298-7kqrl3rv	303	13	,	,	,
cord-347298-7kqrl3rv	303	14	although	although	IN
cord-347298-7kqrl3rv	303	15	expression	expression	NN
cord-347298-7kqrl3rv	303	16	in	in	IN
cord-347298-7kqrl3rv	303	17	the	the	DT
cord-347298-7kqrl3rv	303	18	mouse	mouse	NN
cord-347298-7kqrl3rv	303	19	appears	appear	VBZ
cord-347298-7kqrl3rv	303	20	to	to	TO
cord-347298-7kqrl3rv	303	21	be	be	VB
cord-347298-7kqrl3rv	303	22	more	more	RBR
cord-347298-7kqrl3rv	303	23	restricted	restrict	VBN
cord-347298-7kqrl3rv	304	1	(	(	-LRB-
cord-347298-7kqrl3rv	304	2	Haas	Haas	NNP
cord-347298-7kqrl3rv	304	3	et	et	NNP
cord-347298-7kqrl3rv	304	4	al	al	NNP
cord-347298-7kqrl3rv	304	5	.	.	.
cord-347298-7kqrl3rv	305	1	1988	1988	CD
cord-347298-7kqrl3rv	305	2	;	;	:
cord-347298-7kqrl3rv	305	3	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	305	4	et	et	NNP
cord-347298-7kqrl3rv	305	5	al	al	NNP
cord-347298-7kqrl3rv	305	6	.	.	.
cord-347298-7kqrl3rv	306	1	1995b	1995b	CD
cord-347298-7kqrl3rv	306	2	;	;	:
cord-347298-7kqrl3rv	306	3	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	306	4	and	and	CC
cord-347298-7kqrl3rv	306	5	Niemi	Niemi	NNP
cord-347298-7kqrl3rv	306	6	1987	1987	CD
cord-347298-7kqrl3rv	306	7	;	;	:
cord-347298-7kqrl3rv	306	8	Tung	Tung	NNP
cord-347298-7kqrl3rv	306	9	et	et	NNP
cord-347298-7kqrl3rv	306	10	al	al	NNP
cord-347298-7kqrl3rv	306	11	.	.	NNP
cord-347298-7kqrl3rv	306	12	1987	1987	CD
cord-347298-7kqrl3rv	306	13	)	)	-RRB-
cord-347298-7kqrl3rv	306	14	.	.	.
cord-347298-7kqrl3rv	307	1	A	a	DT
cord-347298-7kqrl3rv	307	2	lack	lack	NN
cord-347298-7kqrl3rv	307	3	of	of	IN
cord-347298-7kqrl3rv	307	4	expression	expression	NN
cord-347298-7kqrl3rv	307	5	of	of	IN
cord-347298-7kqrl3rv	307	6	the	the	DT
cord-347298-7kqrl3rv	307	7	essential	essential	JJ
cord-347298-7kqrl3rv	307	8	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	307	9	molecules	molecule	NNS
cord-347298-7kqrl3rv	307	10	,	,	,
cord-347298-7kqrl3rv	307	11	B7	B7	NNP
cord-347298-7kqrl3rv	307	12	-	-	HYPH
cord-347298-7kqrl3rv	307	13	1	1	CD
cord-347298-7kqrl3rv	307	14	(	(	-LRB-
cord-347298-7kqrl3rv	307	15	CD80	CD80	NNP
cord-347298-7kqrl3rv	307	16	)	)	-RRB-
cord-347298-7kqrl3rv	307	17	and	and	CC
cord-347298-7kqrl3rv	307	18	B7	b7	NN
cord-347298-7kqrl3rv	307	19	-	-	HYPH
cord-347298-7kqrl3rv	307	20	2	2	CD
cord-347298-7kqrl3rv	307	21	(	(	-LRB-
cord-347298-7kqrl3rv	307	22	CD86	CD86	NNP
cord-347298-7kqrl3rv	307	23	)	)	-RRB-
cord-347298-7kqrl3rv	307	24	,	,	,
cord-347298-7kqrl3rv	307	25	has	have	VBZ
cord-347298-7kqrl3rv	307	26	been	be	VBN
cord-347298-7kqrl3rv	307	27	reported	report	VBN
cord-347298-7kqrl3rv	307	28	in	in	IN
cord-347298-7kqrl3rv	307	29	the	the	DT
cord-347298-7kqrl3rv	307	30	mouse	mouse	NN
cord-347298-7kqrl3rv	307	31	testis	testis	NN
cord-347298-7kqrl3rv	307	32	as	as	RB
cord-347298-7kqrl3rv	307	33	well	well	RB
cord-347298-7kqrl3rv	308	1	(	(	-LRB-
cord-347298-7kqrl3rv	308	2	Sainio	Sainio	NNP
cord-347298-7kqrl3rv	308	3	-	-	HYPH
cord-347298-7kqrl3rv	308	4	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	308	5	et	et	FW
cord-347298-7kqrl3rv	308	6	al	al	NNP
cord-347298-7kqrl3rv	308	7	.	.	.
cord-347298-7kqrl3rv	308	8	1996	1996	CD
cord-347298-7kqrl3rv	308	9	)	)	-RRB-
cord-347298-7kqrl3rv	308	10	.	.	.
cord-347298-7kqrl3rv	309	1	Studies	study	NNS
cord-347298-7kqrl3rv	309	2	also	also	RB
cord-347298-7kqrl3rv	309	3	indicate	indicate	VBP
cord-347298-7kqrl3rv	309	4	that	that	IN
cord-347298-7kqrl3rv	309	5	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	309	6	from	from	IN
cord-347298-7kqrl3rv	309	7	the	the	DT
cord-347298-7kqrl3rv	309	8	rat	rat	NN
cord-347298-7kqrl3rv	309	9	testis	testis	NN
cord-347298-7kqrl3rv	309	10	have	have	VBP
cord-347298-7kqrl3rv	309	11	a	a	DT
cord-347298-7kqrl3rv	309	12	significantly	significantly	RB
cord-347298-7kqrl3rv	309	13	reduced	reduce	VBN
cord-347298-7kqrl3rv	309	14	ability	ability	NN
cord-347298-7kqrl3rv	309	15	to	to	TO
cord-347298-7kqrl3rv	309	16	produce	produce	VB
cord-347298-7kqrl3rv	309	17	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	309	18	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	309	19	,	,	,
cord-347298-7kqrl3rv	309	20	such	such	JJ
cord-347298-7kqrl3rv	309	21	as	as	IN
cord-347298-7kqrl3rv	309	22	IL1	IL1	NNP
cord-347298-7kqrl3rv	309	23	and	and	CC
cord-347298-7kqrl3rv	309	24	TNF	TNF	NNP
cord-347298-7kqrl3rv	309	25	,	,	,
cord-347298-7kqrl3rv	309	26	following	follow	VBG
cord-347298-7kqrl3rv	309	27	activation	activation	NN
cord-347298-7kqrl3rv	309	28	(	(	-LRB-
cord-347298-7kqrl3rv	309	29	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	309	30	et	et	NNP
cord-347298-7kqrl3rv	309	31	al	al	NNP
cord-347298-7kqrl3rv	309	32	.	.	NNP
cord-347298-7kqrl3rv	309	33	2002a	2002a	CD
cord-347298-7kqrl3rv	309	34	;	;	:
cord-347298-7kqrl3rv	309	35	Hayes	Hayes	NNP
cord-347298-7kqrl3rv	309	36	et	et	NNP
cord-347298-7kqrl3rv	309	37	al	al	NNP
cord-347298-7kqrl3rv	309	38	.	.	.
cord-347298-7kqrl3rv	309	39	1996	1996	CD
cord-347298-7kqrl3rv	309	40	;	;	:
cord-347298-7kqrl3rv	309	41	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	309	42	et	et	NNP
cord-347298-7kqrl3rv	309	43	al	al	NNP
cord-347298-7kqrl3rv	309	44	.	.	.
cord-347298-7kqrl3rv	309	45	1996	1996	CD
cord-347298-7kqrl3rv	309	46	)	)	-RRB-
cord-347298-7kqrl3rv	309	47	,	,	,
cord-347298-7kqrl3rv	309	48	and	and	CC
cord-347298-7kqrl3rv	309	49	stimulated	stimulate	VBD
cord-347298-7kqrl3rv	309	50	mouse	mouse	NN
cord-347298-7kqrl3rv	309	51	testicular	testicular	NN
cord-347298-7kqrl3rv	309	52	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	309	53	produce	produce	VBP
cord-347298-7kqrl3rv	309	54	the	the	DT
cord-347298-7kqrl3rv	309	55	anti	anti	JJ
cord-347298-7kqrl3rv	309	56	-	-	JJ
cord-347298-7kqrl3rv	309	57	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	309	58	/	/	SYM
cord-347298-7kqrl3rv	309	59	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	309	60	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	309	61	IL10	IL10	NNP
cord-347298-7kqrl3rv	309	62	and	and	CC
cord-347298-7kqrl3rv	309	63	TGF	TGF	NNP
cord-347298-7kqrl3rv	309	64	1	1	CD
cord-347298-7kqrl3rv	309	65	in	in	IN
cord-347298-7kqrl3rv	309	66	vitro	vitro	FW
cord-347298-7kqrl3rv	310	1	(	(	-LRB-
cord-347298-7kqrl3rv	310	2	Bryniarski	Bryniarski	NNP
cord-347298-7kqrl3rv	310	3	et	et	NNP
cord-347298-7kqrl3rv	310	4	al	al	NNP
cord-347298-7kqrl3rv	310	5	.	.	.
cord-347298-7kqrl3rv	311	1	2004	2004	CD
cord-347298-7kqrl3rv	312	1	(	(	-LRB-
cord-347298-7kqrl3rv	312	2	Bryniarski	Bryniarski	NNP
cord-347298-7kqrl3rv	312	3	et	et	NNP
cord-347298-7kqrl3rv	312	4	al	al	NNP
cord-347298-7kqrl3rv	312	5	.	.	NNP
cord-347298-7kqrl3rv	312	6	,	,	,
cord-347298-7kqrl3rv	312	7	2005	2005	CD
cord-347298-7kqrl3rv	312	8	.	.	.
cord-347298-7kqrl3rv	313	1	While	while	IN
cord-347298-7kqrl3rv	313	2	the	the	DT
cord-347298-7kqrl3rv	313	3	data	datum	NNS
cord-347298-7kqrl3rv	313	4	suggest	suggest	VBP
cord-347298-7kqrl3rv	313	5	that	that	IN
cord-347298-7kqrl3rv	313	6	testicular	testicular	JJ
cord-347298-7kqrl3rv	313	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	313	8	may	may	MD
cord-347298-7kqrl3rv	313	9	have	have	VB
cord-347298-7kqrl3rv	313	10	a	a	DT
cord-347298-7kqrl3rv	313	11	predominantly	predominantly	RB
cord-347298-7kqrl3rv	313	12	anti	anti	JJ
cord-347298-7kqrl3rv	313	13	-	-	JJ
cord-347298-7kqrl3rv	313	14	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	313	15	and/or	and/or	CC
cord-347298-7kqrl3rv	313	16	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	313	17	phenotype	phenotype	NN
cord-347298-7kqrl3rv	313	18	,	,	,
cord-347298-7kqrl3rv	313	19	this	this	DT
cord-347298-7kqrl3rv	313	20	has	have	VBZ
cord-347298-7kqrl3rv	313	21	yet	yet	RB
cord-347298-7kqrl3rv	313	22	to	to	TO
cord-347298-7kqrl3rv	313	23	be	be	VB
cord-347298-7kqrl3rv	313	24	formally	formally	RB
cord-347298-7kqrl3rv	313	25	established	establish	VBN
cord-347298-7kqrl3rv	313	26	.	.	.
cord-347298-7kqrl3rv	314	1	Furthermore	furthermore	RB
cord-347298-7kqrl3rv	314	2	,	,	,
cord-347298-7kqrl3rv	314	3	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	314	4	cells	cell	NNS
cord-347298-7kqrl3rv	314	5	,	,	,
cord-347298-7kqrl3rv	314	6	which	which	WDT
cord-347298-7kqrl3rv	314	7	are	be	VBP
cord-347298-7kqrl3rv	314	8	a	a	DT
cord-347298-7kqrl3rv	314	9	highly	highly	RB
cord-347298-7kqrl3rv	314	10	specialized	specialized	JJ
cord-347298-7kqrl3rv	314	11	macrophage	macrophage	NN
cord-347298-7kqrl3rv	314	12	subset	subset	NN
cord-347298-7kqrl3rv	314	13	also	also	RB
cord-347298-7kqrl3rv	314	14	found	find	VBD
cord-347298-7kqrl3rv	314	15	within	within	IN
cord-347298-7kqrl3rv	314	16	the	the	DT
cord-347298-7kqrl3rv	314	17	testicular	testicular	NNP
cord-347298-7kqrl3rv	314	18	interstitium	interstitium	NNP
cord-347298-7kqrl3rv	315	1	(	(	-LRB-
cord-347298-7kqrl3rv	315	2	Fijak	Fijak	NNP
cord-347298-7kqrl3rv	315	3	et	et	FW
cord-347298-7kqrl3rv	315	4	al	al	NNP
cord-347298-7kqrl3rv	315	5	.	.	.
cord-347298-7kqrl3rv	316	1	2005	2005	CD
cord-347298-7kqrl3rv	316	2	;	;	:
cord-347298-7kqrl3rv	316	3	Hoek	Hoek	NNP
cord-347298-7kqrl3rv	316	4	et	et	NNP
cord-347298-7kqrl3rv	316	5	al	al	NNP
cord-347298-7kqrl3rv	316	6	.	.	.
cord-347298-7kqrl3rv	317	1	1997	1997	CD
cord-347298-7kqrl3rv	317	2	;	;	:
cord-347298-7kqrl3rv	317	3	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	317	4	et	et	NNP
cord-347298-7kqrl3rv	317	5	al	al	NNP
cord-347298-7kqrl3rv	317	6	.	.	.
cord-347298-7kqrl3rv	318	1	1995b	1995b	CD
cord-347298-7kqrl3rv	318	2	;	;	:
cord-347298-7kqrl3rv	318	3	Rival	Rival	NNP
cord-347298-7kqrl3rv	318	4	et	et	NNP
cord-347298-7kqrl3rv	318	5	al	al	NNP
cord-347298-7kqrl3rv	318	6	.	.	NNP
cord-347298-7kqrl3rv	318	7	2006a	2006a	CD
cord-347298-7kqrl3rv	318	8	)	)	-RRB-
cord-347298-7kqrl3rv	318	9	,	,	,
cord-347298-7kqrl3rv	318	10	presumably	presumably	RB
cord-347298-7kqrl3rv	318	11	play	play	VBP
cord-347298-7kqrl3rv	318	12	a	a	DT
cord-347298-7kqrl3rv	318	13	more	more	RBR
cord-347298-7kqrl3rv	318	14	important	important	JJ
cord-347298-7kqrl3rv	318	15	role	role	NN
cord-347298-7kqrl3rv	318	16	in	in	IN
cord-347298-7kqrl3rv	318	17	controlling	control	VBG
cord-347298-7kqrl3rv	318	18	immune	immune	JJ
cord-347298-7kqrl3rv	318	19	responses	response	NNS
cord-347298-7kqrl3rv	318	20	to	to	IN
cord-347298-7kqrl3rv	318	21	antigens	antigen	NNS
cord-347298-7kqrl3rv	318	22	within	within	IN
cord-347298-7kqrl3rv	318	23	the	the	DT
cord-347298-7kqrl3rv	318	24	testis	testis	NN
cord-347298-7kqrl3rv	318	25	(	(	-LRB-
cord-347298-7kqrl3rv	318	26	Fijak	Fijak	NNP
cord-347298-7kqrl3rv	318	27	et	et	FW
cord-347298-7kqrl3rv	318	28	al	al	NNP
cord-347298-7kqrl3rv	318	29	.	.	NNP
cord-347298-7kqrl3rv	318	30	2005	2005	CD
cord-347298-7kqrl3rv	318	31	;	;	.
cord-347298-7kqrl3rv	319	1	Rival	rival	NN
cord-347298-7kqrl3rv	319	2	et	et	NNP
cord-347298-7kqrl3rv	319	3	al	al	NNP
cord-347298-7kqrl3rv	319	4	.	.	.
cord-347298-7kqrl3rv	320	1	2006a	2006a	CD
cord-347298-7kqrl3rv	321	1	Rival	rival	NN
cord-347298-7kqrl3rv	321	2	et	et	NNP
cord-347298-7kqrl3rv	321	3	al	al	NNP
cord-347298-7kqrl3rv	321	4	.	.	NNP
cord-347298-7kqrl3rv	321	5	,	,	,
cord-347298-7kqrl3rv	321	6	2007	2007	CD
cord-347298-7kqrl3rv	321	7	.	.	.
cord-347298-7kqrl3rv	322	1	In	in	IN
cord-347298-7kqrl3rv	322	2	the	the	DT
cord-347298-7kqrl3rv	322	3	rat	rat	NN
cord-347298-7kqrl3rv	322	4	testis	testis	NN
cord-347298-7kqrl3rv	322	5	,	,	,
cord-347298-7kqrl3rv	322	6	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	322	7	can	can	MD
cord-347298-7kqrl3rv	322	8	be	be	VB
cord-347298-7kqrl3rv	322	9	discriminated	discriminate	VBN
cord-347298-7kqrl3rv	322	10	by	by	IN
cord-347298-7kqrl3rv	322	11	their	-PRON-	PRP$
cord-347298-7kqrl3rv	322	12	differential	differential	JJ
cord-347298-7kqrl3rv	322	13	expression	expression	NN
cord-347298-7kqrl3rv	322	14	of	of	IN
cord-347298-7kqrl3rv	322	15	two	two	CD
cord-347298-7kqrl3rv	322	16	molecular	molecular	JJ
cord-347298-7kqrl3rv	322	17	markers	marker	NNS
cord-347298-7kqrl3rv	322	18	recognized	recognize	VBN
cord-347298-7kqrl3rv	322	19	by	by	IN
cord-347298-7kqrl3rv	322	20	the	the	DT
cord-347298-7kqrl3rv	322	21	antibodies	antibody	NNS
cord-347298-7kqrl3rv	322	22	ED1	ED1	NNP
cord-347298-7kqrl3rv	322	23	and	and	CC
cord-347298-7kqrl3rv	322	24	ED2	ED2	NNP
cord-347298-7kqrl3rv	322	25	.	.	.
cord-347298-7kqrl3rv	323	1	Antibody	Antibody	NNP
cord-347298-7kqrl3rv	323	2	ED1	ED1	NNP
cord-347298-7kqrl3rv	323	3	recognizes	recognize	VBZ
cord-347298-7kqrl3rv	323	4	the	the	DT
cord-347298-7kqrl3rv	323	5	lysosomal	lysosomal	JJ
cord-347298-7kqrl3rv	323	6	protein	protein	NN
cord-347298-7kqrl3rv	323	7	CD68	CD68	NNP
cord-347298-7kqrl3rv	323	8	,	,	,
cord-347298-7kqrl3rv	323	9	which	which	WDT
cord-347298-7kqrl3rv	323	10	is	be	VBZ
cord-347298-7kqrl3rv	323	11	associated	associate	VBN
cord-347298-7kqrl3rv	323	12	with	with	IN
cord-347298-7kqrl3rv	323	13	antigen	antigen	NN
cord-347298-7kqrl3rv	323	14	processing	processing	NN
cord-347298-7kqrl3rv	323	15	and	and	CC
cord-347298-7kqrl3rv	323	16	presentation	presentation	NN
cord-347298-7kqrl3rv	323	17	(	(	-LRB-
cord-347298-7kqrl3rv	323	18	Groisman	Groisman	NNP
cord-347298-7kqrl3rv	323	19	et	et	FW
cord-347298-7kqrl3rv	323	20	al	al	NNP
cord-347298-7kqrl3rv	323	21	.	.	.
cord-347298-7kqrl3rv	323	22	2002	2002	CD
cord-347298-7kqrl3rv	323	23	)	)	-RRB-
cord-347298-7kqrl3rv	323	24	,	,	,
cord-347298-7kqrl3rv	323	25	while	while	IN
cord-347298-7kqrl3rv	323	26	ED2	ED2	NNP
cord-347298-7kqrl3rv	323	27	recognizes	recognize	VBZ
cord-347298-7kqrl3rv	323	28	the	the	DT
cord-347298-7kqrl3rv	323	29	scavenger	scavenger	NN
cord-347298-7kqrl3rv	323	30	receptor	receptor	NN
cord-347298-7kqrl3rv	323	31	CD163	CD163	NNP
cord-347298-7kqrl3rv	324	1	(	(	-LRB-
cord-347298-7kqrl3rv	324	2	Fabriek	Fabriek	NNP
cord-347298-7kqrl3rv	324	3	et	et	NNP
cord-347298-7kqrl3rv	324	4	al	al	NNP
cord-347298-7kqrl3rv	324	5	.	.	NNP
cord-347298-7kqrl3rv	324	6	2005	2005	CD
cord-347298-7kqrl3rv	324	7	)	)	-RRB-
cord-347298-7kqrl3rv	324	8	.	.	.
cord-347298-7kqrl3rv	325	1	CD163	CD163	NNP
cord-347298-7kqrl3rv	325	2	is	be	VBZ
cord-347298-7kqrl3rv	325	3	involved	involve	VBN
cord-347298-7kqrl3rv	325	4	in	in	IN
cord-347298-7kqrl3rv	325	5	the	the	DT
cord-347298-7kqrl3rv	325	6	clearance	clearance	NN
cord-347298-7kqrl3rv	325	7	of	of	IN
cord-347298-7kqrl3rv	325	8	hemoglobin	hemoglobin	NN
cord-347298-7kqrl3rv	325	9	:	:	:
cord-347298-7kqrl3rv	325	10	haptoglobin	haptoglobin	NN
cord-347298-7kqrl3rv	325	11	complexes	complex	NNS
cord-347298-7kqrl3rv	325	12	and	and	CC
cord-347298-7kqrl3rv	325	13	the	the	DT
cord-347298-7kqrl3rv	325	14	resolution	resolution	NN
cord-347298-7kqrl3rv	325	15	of	of	IN
cord-347298-7kqrl3rv	325	16	inflammation	inflammation	NN
cord-347298-7kqrl3rv	325	17	(	(	-LRB-
cord-347298-7kqrl3rv	325	18	Philippidis	Philippidis	NNP
cord-347298-7kqrl3rv	325	19	et	et	FW
cord-347298-7kqrl3rv	325	20	al	al	NNP
cord-347298-7kqrl3rv	325	21	.	.	.
cord-347298-7kqrl3rv	325	22	2004	2004	CD
cord-347298-7kqrl3rv	325	23	)	)	-RRB-
cord-347298-7kqrl3rv	325	24	.	.	.
cord-347298-7kqrl3rv	326	1	About	about	RB
cord-347298-7kqrl3rv	326	2	80	80	CD
cord-347298-7kqrl3rv	326	3	-	-	SYM
cord-347298-7kqrl3rv	326	4	85	85	CD
cord-347298-7kqrl3rv	326	5	%	%	NN
cord-347298-7kqrl3rv	326	6	of	of	IN
cord-347298-7kqrl3rv	326	7	rat	rat	NN
cord-347298-7kqrl3rv	326	8	testicular	testicular	NNP
cord-347298-7kqrl3rv	326	9	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	326	10	express	express	VBP
cord-347298-7kqrl3rv	326	11	this	this	DT
cord-347298-7kqrl3rv	326	12	scavenger	scavenger	NN
cord-347298-7kqrl3rv	326	13	receptor	receptor	NN
cord-347298-7kqrl3rv	326	14	and	and	CC
cord-347298-7kqrl3rv	326	15	about	about	IN
cord-347298-7kqrl3rv	326	16	half	half	NN
cord-347298-7kqrl3rv	326	17	of	of	IN
cord-347298-7kqrl3rv	326	18	these	these	DT
cord-347298-7kqrl3rv	326	19	cells	cell	NNS
cord-347298-7kqrl3rv	326	20	also	also	RB
cord-347298-7kqrl3rv	326	21	lack	lack	VBP
cord-347298-7kqrl3rv	326	22	expression	expression	NN
cord-347298-7kqrl3rv	326	23	of	of	IN
cord-347298-7kqrl3rv	326	24	CD68	CD68	NNP
cord-347298-7kqrl3rv	326	25	(	(	-LRB-
cord-347298-7kqrl3rv	326	26	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	326	27	et	et	FW
cord-347298-7kqrl3rv	326	28	al	al	NNP
cord-347298-7kqrl3rv	326	29	.	.	NNP
cord-347298-7kqrl3rv	326	30	2002a	2002a	CD
cord-347298-7kqrl3rv	326	31	;	;	:
cord-347298-7kqrl3rv	326	32	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	326	33	et	et	NNP
cord-347298-7kqrl3rv	326	34	al	al	NNP
cord-347298-7kqrl3rv	326	35	.	.	NNP
cord-347298-7kqrl3rv	326	36	1998	1998	CD
cord-347298-7kqrl3rv	326	37	;	;	:
cord-347298-7kqrl3rv	326	38	Wang	Wang	NNP
cord-347298-7kqrl3rv	326	39	et	et	NNP
cord-347298-7kqrl3rv	326	40	al	al	NNP
cord-347298-7kqrl3rv	326	41	.	.	.
cord-347298-7kqrl3rv	326	42	1994	1994	CD
cord-347298-7kqrl3rv	326	43	)	)	-RRB-
cord-347298-7kqrl3rv	326	44	.	.	.
cord-347298-7kqrl3rv	327	1	In	in	IN
cord-347298-7kqrl3rv	327	2	the	the	DT
cord-347298-7kqrl3rv	327	3	human	human	JJ
cord-347298-7kqrl3rv	327	4	testis	testis	NN
cord-347298-7kqrl3rv	327	5	,	,	,
cord-347298-7kqrl3rv	327	6	most	most	JJS
cord-347298-7kqrl3rv	327	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	327	8	appear	appear	VBP
cord-347298-7kqrl3rv	327	9	to	to	TO
cord-347298-7kqrl3rv	327	10	be	be	VB
cord-347298-7kqrl3rv	327	11	CD68	CD68	NNP
cord-347298-7kqrl3rv	327	12	þ	þ	NNP
cord-347298-7kqrl3rv	327	13	,	,	,
cord-347298-7kqrl3rv	327	14	but	but	CC
cord-347298-7kqrl3rv	327	15	expression	expression	NN
cord-347298-7kqrl3rv	327	16	of	of	IN
cord-347298-7kqrl3rv	327	17	CD163	CD163	NNP
cord-347298-7kqrl3rv	327	18	is	be	VBZ
cord-347298-7kqrl3rv	327	19	a	a	DT
cord-347298-7kqrl3rv	327	20	feature	feature	NN
cord-347298-7kqrl3rv	327	21	of	of	IN
cord-347298-7kqrl3rv	327	22	a	a	DT
cord-347298-7kqrl3rv	327	23	subset	subset	NN
cord-347298-7kqrl3rv	327	24	of	of	IN
cord-347298-7kqrl3rv	327	25	these	these	DT
cord-347298-7kqrl3rv	327	26	cells	cell	NNS
cord-347298-7kqrl3rv	327	27	as	as	RB
cord-347298-7kqrl3rv	327	28	well	well	RB
cord-347298-7kqrl3rv	328	1	(	(	-LRB-
cord-347298-7kqrl3rv	328	2	Frungieri	Frungieri	NNP
cord-347298-7kqrl3rv	328	3	et	et	FW
cord-347298-7kqrl3rv	328	4	al	al	NNP
cord-347298-7kqrl3rv	328	5	.	.	.
cord-347298-7kqrl3rv	328	6	2002	2002	CD
cord-347298-7kqrl3rv	328	7	)	)	-RRB-
cord-347298-7kqrl3rv	328	8	.	.	.
cord-347298-7kqrl3rv	329	1	The	the	DT
cord-347298-7kqrl3rv	329	2	heterogeneous	heterogeneous	JJ
cord-347298-7kqrl3rv	329	3	expression	expression	NN
cord-347298-7kqrl3rv	329	4	of	of	IN
cord-347298-7kqrl3rv	329	5	these	these	DT
cord-347298-7kqrl3rv	329	6	two	two	CD
cord-347298-7kqrl3rv	329	7	markers	marker	NNS
cord-347298-7kqrl3rv	329	8	points	point	NNS
cord-347298-7kqrl3rv	329	9	to	to	IN
cord-347298-7kqrl3rv	329	10	the	the	DT
cord-347298-7kqrl3rv	329	11	existence	existence	NN
cord-347298-7kqrl3rv	329	12	of	of	IN
cord-347298-7kqrl3rv	329	13	multiple	multiple	JJ
cord-347298-7kqrl3rv	329	14	populations	population	NNS
cord-347298-7kqrl3rv	329	15	of	of	IN
cord-347298-7kqrl3rv	329	16	testicular	testicular	JJ
cord-347298-7kqrl3rv	329	17	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	329	18	,	,	,
cord-347298-7kqrl3rv	329	19	and	and	CC
cord-347298-7kqrl3rv	329	20	evidence	evidence	NN
cord-347298-7kqrl3rv	329	21	suggests	suggest	VBZ
cord-347298-7kqrl3rv	329	22	that	that	IN
cord-347298-7kqrl3rv	329	23	these	these	DT
cord-347298-7kqrl3rv	329	24	phenotypic	phenotypic	JJ
cord-347298-7kqrl3rv	329	25	differences	difference	NNS
cord-347298-7kqrl3rv	329	26	also	also	RB
cord-347298-7kqrl3rv	329	27	correspond	correspond	VBP
cord-347298-7kqrl3rv	329	28	to	to	IN
cord-347298-7kqrl3rv	329	29	functional	functional	JJ
cord-347298-7kqrl3rv	329	30	differences	difference	NNS
cord-347298-7kqrl3rv	329	31	.	.	.
cord-347298-7kqrl3rv	330	1	In	in	IN
cord-347298-7kqrl3rv	330	2	the	the	DT
cord-347298-7kqrl3rv	330	3	normal	normal	JJ
cord-347298-7kqrl3rv	330	4	and	and	CC
cord-347298-7kqrl3rv	330	5	inflamed	inflamed	JJ
cord-347298-7kqrl3rv	330	6	adult	adult	NN
cord-347298-7kqrl3rv	330	7	rat	rat	NN
cord-347298-7kqrl3rv	330	8	testis	testis	NN
cord-347298-7kqrl3rv	330	9	,	,	,
cord-347298-7kqrl3rv	330	10	CD163	CD163	NNP
cord-347298-7kqrl3rv	330	11	þ	þ	NNP
cord-347298-7kqrl3rv	330	12	cells	cell	NNS
cord-347298-7kqrl3rv	330	13	lack	lack	VBP
cord-347298-7kqrl3rv	330	14	expression	expression	NN
cord-347298-7kqrl3rv	330	15	of	of	IN
cord-347298-7kqrl3rv	330	16	the	the	DT
cord-347298-7kqrl3rv	330	17	key	key	JJ
cord-347298-7kqrl3rv	330	18	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	330	19	mediators	mediator	NNS
cord-347298-7kqrl3rv	330	20	IL1	IL1	NNP
cord-347298-7kqrl3rv	330	21	and	and	CC
cord-347298-7kqrl3rv	330	22	inducible	inducible	JJ
cord-347298-7kqrl3rv	330	23	nitric	nitric	NN
cord-347298-7kqrl3rv	330	24	oxide	oxide	NN
cord-347298-7kqrl3rv	330	25	synthase	synthase	NN
cord-347298-7kqrl3rv	330	26	(	(	-LRB-
cord-347298-7kqrl3rv	330	27	iNOS	inos	NN
cord-347298-7kqrl3rv	330	28	)	)	-RRB-
cord-347298-7kqrl3rv	330	29	,	,	,
cord-347298-7kqrl3rv	330	30	as	as	IN
cord-347298-7kqrl3rv	330	31	measured	measure	VBN
cord-347298-7kqrl3rv	330	32	by	by	IN
cord-347298-7kqrl3rv	330	33	double	double	JJ
cord-347298-7kqrl3rv	330	34	-	-	HYPH
cord-347298-7kqrl3rv	330	35	label	label	NN
cord-347298-7kqrl3rv	330	36	immunohistochemistry	immunohistochemistry	NN
cord-347298-7kqrl3rv	330	37	,	,	,
cord-347298-7kqrl3rv	330	38	but	but	CC
cord-347298-7kqrl3rv	330	39	these	these	DT
cord-347298-7kqrl3rv	330	40	molecules	molecule	NNS
cord-347298-7kqrl3rv	330	41	are	be	VBP
cord-347298-7kqrl3rv	330	42	detectable	detectable	JJ
cord-347298-7kqrl3rv	330	43	in	in	IN
cord-347298-7kqrl3rv	330	44	CD68	CD68	NNP
cord-347298-7kqrl3rv	330	45	þ	þ	CD
cord-347298-7kqrl3rv	330	46	cells	cell	NNS
cord-347298-7kqrl3rv	330	47	that	that	WDT
cord-347298-7kqrl3rv	330	48	do	do	VBP
cord-347298-7kqrl3rv	330	49	not	not	RB
cord-347298-7kqrl3rv	330	50	express	express	VB
cord-347298-7kqrl3rv	330	51	CD163	CD163	NNP
cord-347298-7kqrl3rv	330	52	(	(	-LRB-
cord-347298-7kqrl3rv	330	53	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	330	54	et	et	NNP
cord-347298-7kqrl3rv	330	55	al	al	NNP
cord-347298-7kqrl3rv	330	56	.	.	NNP
cord-347298-7kqrl3rv	330	57	2002a	2002a	CD
cord-347298-7kqrl3rv	330	58	;	;	:
cord-347298-7kqrl3rv	330	59	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	330	60	et	et	NNP
cord-347298-7kqrl3rv	330	61	al	al	NNP
cord-347298-7kqrl3rv	330	62	.	.	NNP
cord-347298-7kqrl3rv	330	63	2005	2005	CD
cord-347298-7kqrl3rv	330	64	)	)	-RRB-
cord-347298-7kqrl3rv	330	65	.	.	.
cord-347298-7kqrl3rv	331	1	Indeed	indeed	RB
cord-347298-7kqrl3rv	331	2	,	,	,
cord-347298-7kqrl3rv	331	3	purification	purification	NN
cord-347298-7kqrl3rv	331	4	of	of	IN
cord-347298-7kqrl3rv	331	5	CD163	CD163	NNP
cord-347298-7kqrl3rv	331	6	þ	þ	NNP
cord-347298-7kqrl3rv	331	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	331	8	from	from	IN
cord-347298-7kqrl3rv	331	9	the	the	DT
cord-347298-7kqrl3rv	331	10	rat	rat	NN
cord-347298-7kqrl3rv	331	11	testis	testis	NN
cord-347298-7kqrl3rv	331	12	using	use	VBG
cord-347298-7kqrl3rv	331	13	immunomagnetic	immunomagnetic	JJ
cord-347298-7kqrl3rv	331	14	beads	bead	NNS
cord-347298-7kqrl3rv	331	15	confirms	confirm	VBZ
cord-347298-7kqrl3rv	331	16	that	that	IN
cord-347298-7kqrl3rv	331	17	these	these	DT
cord-347298-7kqrl3rv	331	18	cells	cell	NNS
cord-347298-7kqrl3rv	331	19	have	have	VBP
cord-347298-7kqrl3rv	331	20	reduced	reduce	VBN
cord-347298-7kqrl3rv	331	21	capacity	capacity	NN
cord-347298-7kqrl3rv	331	22	to	to	TO
cord-347298-7kqrl3rv	331	23	produce	produce	VB
cord-347298-7kqrl3rv	331	24	IL1	IL1	NNP
cord-347298-7kqrl3rv	331	25	,	,	,
cord-347298-7kqrl3rv	331	26	IL6	IL6	NNP
cord-347298-7kqrl3rv	331	27	,	,	,
cord-347298-7kqrl3rv	331	28	or	or	CC
cord-347298-7kqrl3rv	332	1	NO	no	RB
cord-347298-7kqrl3rv	332	2	upon	upon	IN
cord-347298-7kqrl3rv	332	3	stimulation	stimulation	NN
cord-347298-7kqrl3rv	332	4	,	,	,
cord-347298-7kqrl3rv	332	5	although	although	IN
cord-347298-7kqrl3rv	332	6	they	-PRON-	PRP
cord-347298-7kqrl3rv	332	7	retain	retain	VBP
cord-347298-7kqrl3rv	332	8	the	the	DT
cord-347298-7kqrl3rv	332	9	ability	ability	NN
cord-347298-7kqrl3rv	332	10	to	to	TO
cord-347298-7kqrl3rv	332	11	produce	produce	VB
cord-347298-7kqrl3rv	332	12	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	332	13	(	(	-LRB-
cord-347298-7kqrl3rv	332	14	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	332	15	et	et	NNP
cord-347298-7kqrl3rv	332	16	al	al	NNP
cord-347298-7kqrl3rv	332	17	.	.	NNP
cord-347298-7kqrl3rv	332	18	2002a	2002a	CD
cord-347298-7kqrl3rv	332	19	;	;	:
cord-347298-7kqrl3rv	332	20	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	332	21	,	,	,
cord-347298-7kqrl3rv	332	22	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	332	23	data	datum	NNS
cord-347298-7kqrl3rv	332	24	)	)	-RRB-
cord-347298-7kqrl3rv	332	25	.	.	.
cord-347298-7kqrl3rv	333	1	This	this	DT
cord-347298-7kqrl3rv	333	2	suggests	suggest	VBZ
cord-347298-7kqrl3rv	333	3	that	that	IN
cord-347298-7kqrl3rv	333	4	the	the	DT
cord-347298-7kqrl3rv	333	5	CD163	CD163	NNP
cord-347298-7kqrl3rv	333	6	þ	þ	NNP
cord-347298-7kqrl3rv	333	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	333	8	have	have	VBP
cord-347298-7kqrl3rv	333	9	reduced	reduce	VBN
cord-347298-7kqrl3rv	333	10	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	333	11	activities	activity	NNS
cord-347298-7kqrl3rv	333	12	,	,	,
cord-347298-7kqrl3rv	333	13	while	while	IN
cord-347298-7kqrl3rv	333	14	the	the	DT
cord-347298-7kqrl3rv	333	15	CD163-negative	CD163-negative	NNP
cord-347298-7kqrl3rv	333	16	testicular	testicular	JJ
cord-347298-7kqrl3rv	333	17	macrophage	macrophage	NN
cord-347298-7kqrl3rv	333	18	population	population	NN
cord-347298-7kqrl3rv	333	19	retains	retain	VBZ
cord-347298-7kqrl3rv	333	20	normal	normal	JJ
cord-347298-7kqrl3rv	333	21	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	333	22	functions	function	NNS
cord-347298-7kqrl3rv	333	23	.	.	.
cord-347298-7kqrl3rv	334	1	This	this	DT
cord-347298-7kqrl3rv	334	2	observation	observation	NN
cord-347298-7kqrl3rv	334	3	is	be	VBZ
cord-347298-7kqrl3rv	334	4	important	important	JJ
cord-347298-7kqrl3rv	334	5	because	because	IN
cord-347298-7kqrl3rv	334	6	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	334	7	that	that	WDT
cord-347298-7kqrl3rv	334	8	express	express	VBP
cord-347298-7kqrl3rv	334	9	CD163	CD163	NNP
cord-347298-7kqrl3rv	334	10	and	and	CC
cord-347298-7kqrl3rv	334	11	produce	produce	VB
cord-347298-7kqrl3rv	334	12	IL10	IL10	NNP
cord-347298-7kqrl3rv	334	13	,	,	,
cord-347298-7kqrl3rv	334	14	but	but	CC
cord-347298-7kqrl3rv	334	15	display	display	NN
cord-347298-7kqrl3rv	334	16	reduced	reduce	VBN
cord-347298-7kqrl3rv	334	17	expression	expression	NN
cord-347298-7kqrl3rv	334	18	of	of	IN
cord-347298-7kqrl3rv	334	19	CD80	CD80	NNP
cord-347298-7kqrl3rv	334	20	,	,	,
cord-347298-7kqrl3rv	334	21	CD86	CD86	NNP
cord-347298-7kqrl3rv	334	22	,	,	,
cord-347298-7kqrl3rv	334	23	iNOS	inos	CD
cord-347298-7kqrl3rv	334	24	,	,	,
cord-347298-7kqrl3rv	334	25	TNF	TNF	NNP
cord-347298-7kqrl3rv	334	26	,	,	,
cord-347298-7kqrl3rv	334	27	and	and	CC
cord-347298-7kqrl3rv	334	28	IL1	IL1	NNP
cord-347298-7kqrl3rv	334	29	,	,	,
cord-347298-7kqrl3rv	334	30	are	be	VBP
cord-347298-7kqrl3rv	334	31	polarized	polarize	VBN
cord-347298-7kqrl3rv	334	32	toward	toward	IN
cord-347298-7kqrl3rv	334	33	the	the	DT
cord-347298-7kqrl3rv	334	34	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	334	35	M2	M2	NNP
cord-347298-7kqrl3rv	334	36	subset	subset	VBN
cord-347298-7kqrl3rv	334	37	(	(	-LRB-
cord-347298-7kqrl3rv	334	38	Mantovani	Mantovani	NNP
cord-347298-7kqrl3rv	334	39	et	et	NNP
cord-347298-7kqrl3rv	334	40	al	al	NNP
cord-347298-7kqrl3rv	334	41	.	.	NNP
cord-347298-7kqrl3rv	334	42	2005	2005	CD
cord-347298-7kqrl3rv	334	43	;	;	:
cord-347298-7kqrl3rv	334	44	Sica	Sica	NNP
cord-347298-7kqrl3rv	334	45	et	et	NNP
cord-347298-7kqrl3rv	334	46	al	al	NNP
cord-347298-7kqrl3rv	334	47	.	.	NNP
cord-347298-7kqrl3rv	334	48	2008	2008	CD
cord-347298-7kqrl3rv	334	49	)	)	-RRB-
cord-347298-7kqrl3rv	334	50	.	.	.
cord-347298-7kqrl3rv	335	1	The	the	DT
cord-347298-7kqrl3rv	335	2	M2	M2	NNP
cord-347298-7kqrl3rv	335	3	macrophage	macrophage	NN
cord-347298-7kqrl3rv	335	4	subset	subset	NN
cord-347298-7kqrl3rv	335	5	is	be	VBZ
cord-347298-7kqrl3rv	335	6	analogous	analogous	JJ
cord-347298-7kqrl3rv	335	7	to	to	IN
cord-347298-7kqrl3rv	335	8	the	the	DT
cord-347298-7kqrl3rv	335	9	Th2	th2	CD
cord-347298-7kqrl3rv	335	10	subset	subset	VBN
cord-347298-7kqrl3rv	335	11	among	among	IN
cord-347298-7kqrl3rv	335	12	T	T	NNP
cord-347298-7kqrl3rv	335	13	cells	cell	NNS
cord-347298-7kqrl3rv	335	14	,	,	,
cord-347298-7kqrl3rv	335	15	and	and	CC
cord-347298-7kqrl3rv	335	16	is	be	VBZ
cord-347298-7kqrl3rv	335	17	associated	associate	VBN
cord-347298-7kqrl3rv	335	18	with	with	IN
cord-347298-7kqrl3rv	335	19	late	late	JJ
cord-347298-7kqrl3rv	335	20	-	-	HYPH
cord-347298-7kqrl3rv	335	21	stage	stage	NN
cord-347298-7kqrl3rv	335	22	inflammation	inflammation	NN
cord-347298-7kqrl3rv	335	23	and	and	CC
cord-347298-7kqrl3rv	335	24	its	-PRON-	PRP$
cord-347298-7kqrl3rv	335	25	resolution	resolution	NN
cord-347298-7kqrl3rv	335	26	,	,	,
cord-347298-7kqrl3rv	335	27	as	as	RB
cord-347298-7kqrl3rv	335	28	well	well	RB
cord-347298-7kqrl3rv	335	29	as	as	IN
cord-347298-7kqrl3rv	335	30	tumors	tumor	NNS
cord-347298-7kqrl3rv	335	31	and	and	CC
cord-347298-7kqrl3rv	335	32	other	other	JJ
cord-347298-7kqrl3rv	335	33	immunologically	immunologically	RB
cord-347298-7kqrl3rv	335	34	privileged	privileged	JJ
cord-347298-7kqrl3rv	335	35	tissue	tissue	NN
cord-347298-7kqrl3rv	335	36	sites	site	NNS
cord-347298-7kqrl3rv	335	37	.	.	.
cord-347298-7kqrl3rv	336	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	336	2	would	would	MD
cord-347298-7kqrl3rv	336	3	appear	appear	VB
cord-347298-7kqrl3rv	336	4	that	that	IN
cord-347298-7kqrl3rv	336	5	a	a	DT
cord-347298-7kqrl3rv	336	6	significant	significant	JJ
cord-347298-7kqrl3rv	336	7	proportion	proportion	NN
cord-347298-7kqrl3rv	336	8	of	of	IN
cord-347298-7kqrl3rv	336	9	the	the	DT
cord-347298-7kqrl3rv	336	10	resident	resident	JJ
cord-347298-7kqrl3rv	336	11	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	336	12	of	of	IN
cord-347298-7kqrl3rv	336	13	the	the	DT
cord-347298-7kqrl3rv	336	14	testis	testis	NN
cord-347298-7kqrl3rv	336	15	possess	possess	VBP
cord-347298-7kqrl3rv	336	16	an	an	DT
cord-347298-7kqrl3rv	336	17	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	336	18	phenotype	phenotype	NN
cord-347298-7kqrl3rv	336	19	that	that	WDT
cord-347298-7kqrl3rv	336	20	is	be	VBZ
cord-347298-7kqrl3rv	336	21	consistent	consistent	JJ
cord-347298-7kqrl3rv	336	22	with	with	IN
cord-347298-7kqrl3rv	336	23	immune	immune	JJ
cord-347298-7kqrl3rv	336	24	privilege	privilege	NN
cord-347298-7kqrl3rv	336	25	.	.	.
cord-347298-7kqrl3rv	337	1	The	the	DT
cord-347298-7kqrl3rv	337	2	functional	functional	JJ
cord-347298-7kqrl3rv	337	3	roles	role	NNS
cord-347298-7kqrl3rv	337	4	of	of	IN
cord-347298-7kqrl3rv	337	5	this	this	DT
cord-347298-7kqrl3rv	337	6	macrophage	macrophage	NN
cord-347298-7kqrl3rv	337	7	population	population	NN
cord-347298-7kqrl3rv	337	8	,	,	,
cord-347298-7kqrl3rv	337	9	as	as	RB
cord-347298-7kqrl3rv	337	10	well	well	RB
cord-347298-7kqrl3rv	337	11	as	as	IN
cord-347298-7kqrl3rv	337	12	those	those	DT
cord-347298-7kqrl3rv	337	13	of	of	IN
cord-347298-7kqrl3rv	337	14	the	the	DT
cord-347298-7kqrl3rv	337	15	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	337	16	that	that	WDT
cord-347298-7kqrl3rv	337	17	appear	appear	VBP
cord-347298-7kqrl3rv	337	18	to	to	TO
cord-347298-7kqrl3rv	337	19	retain	retain	VB
cord-347298-7kqrl3rv	337	20	normal	normal	JJ
cord-347298-7kqrl3rv	337	21	inflammatory	inflammatory	NN
cord-347298-7kqrl3rv	337	22	(	(	-LRB-
cord-347298-7kqrl3rv	337	23	i.e.	i.e.	FW
cord-347298-7kqrl3rv	337	24	,	,	,
cord-347298-7kqrl3rv	337	25	M1	M1	NNP
cord-347298-7kqrl3rv	337	26	subset	subset	NNP
cord-347298-7kqrl3rv	337	27	)	)	-RRB-
cord-347298-7kqrl3rv	337	28	properties	property	NNS
cord-347298-7kqrl3rv	337	29	,	,	,
cord-347298-7kqrl3rv	337	30	demand	demand	VBP
cord-347298-7kqrl3rv	337	31	particular	particular	JJ
cord-347298-7kqrl3rv	337	32	attention	attention	NN
cord-347298-7kqrl3rv	337	33	if	if	IN
cord-347298-7kqrl3rv	337	34	we	-PRON-	PRP
cord-347298-7kqrl3rv	337	35	are	be	VBP
cord-347298-7kqrl3rv	337	36	to	to	TO
cord-347298-7kqrl3rv	337	37	understand	understand	VB
cord-347298-7kqrl3rv	337	38	the	the	DT
cord-347298-7kqrl3rv	337	39	unique	unique	JJ
cord-347298-7kqrl3rv	337	40	immunological	immunological	JJ
cord-347298-7kqrl3rv	337	41	environment	environment	NN
cord-347298-7kqrl3rv	337	42	of	of	IN
cord-347298-7kqrl3rv	337	43	the	the	DT
cord-347298-7kqrl3rv	337	44	testis	testis	NN
cord-347298-7kqrl3rv	337	45	.	.	.
cord-347298-7kqrl3rv	338	1	While	while	IN
cord-347298-7kqrl3rv	338	2	the	the	DT
cord-347298-7kqrl3rv	338	3	functions	function	NNS
cord-347298-7kqrl3rv	338	4	and	and	CC
cord-347298-7kqrl3rv	338	5	regulation	regulation	NN
cord-347298-7kqrl3rv	338	6	of	of	IN
cord-347298-7kqrl3rv	338	7	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	338	8	within	within	IN
cord-347298-7kqrl3rv	338	9	the	the	DT
cord-347298-7kqrl3rv	338	10	testis	testis	NN
cord-347298-7kqrl3rv	338	11	have	have	VBP
cord-347298-7kqrl3rv	338	12	yet	yet	RB
cord-347298-7kqrl3rv	338	13	to	to	TO
cord-347298-7kqrl3rv	338	14	be	be	VB
cord-347298-7kqrl3rv	338	15	properly	properly	RB
cord-347298-7kqrl3rv	338	16	characterized	characterize	VBN
cord-347298-7kqrl3rv	338	17	,	,	,
cord-347298-7kqrl3rv	338	18	by	by	IN
cord-347298-7kqrl3rv	338	19	their	-PRON-	PRP$
cord-347298-7kqrl3rv	338	20	presence	presence	NN
cord-347298-7kqrl3rv	338	21	alone	alone	RB
cord-347298-7kqrl3rv	338	22	these	these	DT
cord-347298-7kqrl3rv	338	23	cells	cell	NNS
cord-347298-7kqrl3rv	338	24	will	will	MD
cord-347298-7kqrl3rv	338	25	have	have	VB
cord-347298-7kqrl3rv	338	26	significant	significant	JJ
cord-347298-7kqrl3rv	338	27	effects	effect	NNS
cord-347298-7kqrl3rv	338	28	on	on	IN
cord-347298-7kqrl3rv	338	29	testicular	testicular	JJ
cord-347298-7kqrl3rv	338	30	events	event	NNS
cord-347298-7kqrl3rv	338	31	.	.	.
cord-347298-7kqrl3rv	339	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	339	2	may	may	MD
cord-347298-7kqrl3rv	339	3	also	also	RB
cord-347298-7kqrl3rv	339	4	be	be	VB
cord-347298-7kqrl3rv	339	5	assumed	assume	VBN
cord-347298-7kqrl3rv	339	6	that	that	IN
cord-347298-7kqrl3rv	339	7	,	,	,
cord-347298-7kqrl3rv	339	8	in	in	IN
cord-347298-7kqrl3rv	339	9	contrast	contrast	NN
cord-347298-7kqrl3rv	339	10	to	to	IN
cord-347298-7kqrl3rv	339	11	the	the	DT
cord-347298-7kqrl3rv	339	12	largely	largely	RB
cord-347298-7kqrl3rv	339	13	resident	resident	JJ
cord-347298-7kqrl3rv	339	14	population	population	NN
cord-347298-7kqrl3rv	339	15	of	of	IN
cord-347298-7kqrl3rv	339	16	testicular	testicular	JJ
cord-347298-7kqrl3rv	339	17	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	339	18	,	,	,
cord-347298-7kqrl3rv	339	19	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	339	20	circulate	circulate	VBP
cord-347298-7kqrl3rv	339	21	through	through	IN
cord-347298-7kqrl3rv	339	22	the	the	DT
cord-347298-7kqrl3rv	339	23	testis	testis	NN
cord-347298-7kqrl3rv	339	24	.	.	.
cord-347298-7kqrl3rv	340	1	This	this	DT
cord-347298-7kqrl3rv	340	2	may	may	MD
cord-347298-7kqrl3rv	340	3	be	be	VB
cord-347298-7kqrl3rv	340	4	because	because	IN
cord-347298-7kqrl3rv	340	5	they	-PRON-	PRP
cord-347298-7kqrl3rv	340	6	possess	possess	VBP
cord-347298-7kqrl3rv	340	7	specificity	specificity	NN
cord-347298-7kqrl3rv	340	8	for	for	IN
cord-347298-7kqrl3rv	340	9	testicular	testicular	JJ
cord-347298-7kqrl3rv	340	10	antigens	antigen	NNS
cord-347298-7kqrl3rv	340	11	,	,	,
cord-347298-7kqrl3rv	340	12	or	or	CC
cord-347298-7kqrl3rv	340	13	because	because	IN
cord-347298-7kqrl3rv	340	14	they	-PRON-	PRP
cord-347298-7kqrl3rv	340	15	have	have	VBP
cord-347298-7kqrl3rv	340	16	been	be	VBN
cord-347298-7kqrl3rv	340	17	activated	activate	VBN
cord-347298-7kqrl3rv	340	18	during	during	IN
cord-347298-7kqrl3rv	340	19	earlier	early	JJR
cord-347298-7kqrl3rv	340	20	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	340	21	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	340	22	or	or	CC
cord-347298-7kqrl3rv	340	23	infectious	infectious	JJ
cord-347298-7kqrl3rv	340	24	events	event	NNS
cord-347298-7kqrl3rv	340	25	(	(	-LRB-
cord-347298-7kqrl3rv	340	26	Czerkinsky	Czerkinsky	NNP
cord-347298-7kqrl3rv	340	27	et	et	NNP
cord-347298-7kqrl3rv	340	28	al	al	NNP
cord-347298-7kqrl3rv	340	29	.	.	.
cord-347298-7kqrl3rv	340	30	1999	1999	CD
cord-347298-7kqrl3rv	340	31	;	;	:
cord-347298-7kqrl3rv	340	32	Springer	Springer	NNP
cord-347298-7kqrl3rv	340	33	1994	1994	CD
cord-347298-7kqrl3rv	340	34	)	)	-RRB-
cord-347298-7kqrl3rv	340	35	.	.	.
cord-347298-7kqrl3rv	341	1	Quantitative	quantitative	JJ
cord-347298-7kqrl3rv	341	2	studies	study	NNS
cord-347298-7kqrl3rv	341	3	in	in	IN
cord-347298-7kqrl3rv	341	4	the	the	DT
cord-347298-7kqrl3rv	341	5	rat	rat	NN
cord-347298-7kqrl3rv	341	6	indicate	indicate	VBP
cord-347298-7kqrl3rv	341	7	that	that	IN
cord-347298-7kqrl3rv	341	8	,	,	,
cord-347298-7kqrl3rv	341	9	at	at	IN
cord-347298-7kqrl3rv	341	10	any	any	DT
cord-347298-7kqrl3rv	341	11	given	give	VBN
cord-347298-7kqrl3rv	341	12	time	time	NN
cord-347298-7kqrl3rv	341	13	,	,	,
cord-347298-7kqrl3rv	341	14	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	341	15	are	be	VBP
cord-347298-7kqrl3rv	341	16	approximately	approximately	RB
cord-347298-7kqrl3rv	341	17	10	10	CD
cord-347298-7kqrl3rv	341	18	%	%	NN
cord-347298-7kqrl3rv	341	19	as	as	RB
cord-347298-7kqrl3rv	341	20	numerous	numerous	JJ
cord-347298-7kqrl3rv	341	21	as	as	IN
cord-347298-7kqrl3rv	341	22	the	the	DT
cord-347298-7kqrl3rv	341	23	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	341	24	in	in	IN
cord-347298-7kqrl3rv	341	25	the	the	DT
cord-347298-7kqrl3rv	341	26	normal	normal	JJ
cord-347298-7kqrl3rv	341	27	testis	testis	NN
cord-347298-7kqrl3rv	341	28	(	(	-LRB-
cord-347298-7kqrl3rv	341	29	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	341	30	and	and	CC
cord-347298-7kqrl3rv	341	31	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	341	32	2000	2000	CD
cord-347298-7kqrl3rv	341	33	;	;	:
cord-347298-7kqrl3rv	341	34	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	341	35	et	et	NNP
cord-347298-7kqrl3rv	341	36	al	al	NNP
cord-347298-7kqrl3rv	341	37	.	.	.
cord-347298-7kqrl3rv	342	1	1998b	1998b	CD
cord-347298-7kqrl3rv	342	2	;	;	:
cord-347298-7kqrl3rv	342	3	Wang	Wang	NNP
cord-347298-7kqrl3rv	342	4	et	et	NNP
cord-347298-7kqrl3rv	342	5	al	al	NNP
cord-347298-7kqrl3rv	342	6	.	.	.
cord-347298-7kqrl3rv	342	7	1994	1994	CD
cord-347298-7kqrl3rv	342	8	)	)	-RRB-
cord-347298-7kqrl3rv	342	9	.	.	.
cord-347298-7kqrl3rv	343	1	In	in	IN
cord-347298-7kqrl3rv	343	2	the	the	DT
cord-347298-7kqrl3rv	343	3	rat	rat	NN
cord-347298-7kqrl3rv	343	4	and	and	CC
cord-347298-7kqrl3rv	343	5	mouse	mouse	NN
cord-347298-7kqrl3rv	343	6	,	,	,
cord-347298-7kqrl3rv	343	7	intratesticular	intratesticular	NNP
cord-347298-7kqrl3rv	343	8	lymphocytes	lymphocytes	NNP
cord-347298-7kqrl3rv	343	9	express	express	VBP
cord-347298-7kqrl3rv	343	10	T	T	NNP
cord-347298-7kqrl3rv	343	11	cell	cell	NN
cord-347298-7kqrl3rv	343	12	and	and	CC
cord-347298-7kqrl3rv	343	13	NK	NK	NNP
cord-347298-7kqrl3rv	343	14	cell	cell	NN
cord-347298-7kqrl3rv	343	15	markers	marker	NNS
cord-347298-7kqrl3rv	343	16	,	,	,
cord-347298-7kqrl3rv	343	17	and	and	CC
cord-347298-7kqrl3rv	343	18	comprise	comprise	VBP
cord-347298-7kqrl3rv	343	19	distinct	distinct	JJ
cord-347298-7kqrl3rv	343	20	T	t	NN
cord-347298-7kqrl3rv	343	21	cell	cell	NN
cord-347298-7kqrl3rv	343	22	,	,	,
cord-347298-7kqrl3rv	343	23	NK	NK	NNP
cord-347298-7kqrl3rv	343	24	cell	cell	NN
cord-347298-7kqrl3rv	343	25	,	,	,
cord-347298-7kqrl3rv	343	26	and	and	CC
cord-347298-7kqrl3rv	343	27	NKT	NKT	NNP
cord-347298-7kqrl3rv	343	28	cell	cell	NN
cord-347298-7kqrl3rv	343	29	subsets	subset	NNS
cord-347298-7kqrl3rv	343	30	(	(	-LRB-
cord-347298-7kqrl3rv	343	31	Tompkins	Tompkins	NNP
cord-347298-7kqrl3rv	343	32	et	et	NNP
cord-347298-7kqrl3rv	343	33	al	al	NNP
cord-347298-7kqrl3rv	343	34	.	.	.
cord-347298-7kqrl3rv	344	1	1998	1998	CD
cord-347298-7kqrl3rv	344	2	;	;	:
cord-347298-7kqrl3rv	344	3	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	344	4	,	,	,
cord-347298-7kqrl3rv	344	5	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	344	6	data	datum	NNS
cord-347298-7kqrl3rv	344	7	)	)	-RRB-
cord-347298-7kqrl3rv	344	8	.	.	.
cord-347298-7kqrl3rv	345	1	Both	both	DT
cord-347298-7kqrl3rv	345	2	T	t	NN
cord-347298-7kqrl3rv	345	3	cell	cell	NN
cord-347298-7kqrl3rv	345	4	and	and	CC
cord-347298-7kqrl3rv	345	5	NK	NK	NNP
cord-347298-7kqrl3rv	345	6	cell	cell	NN
cord-347298-7kqrl3rv	345	7	markers	marker	NNS
cord-347298-7kqrl3rv	345	8	are	be	VBP
cord-347298-7kqrl3rv	345	9	expressed	express	VBN
cord-347298-7kqrl3rv	345	10	by	by	IN
cord-347298-7kqrl3rv	345	11	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	345	12	in	in	IN
cord-347298-7kqrl3rv	345	13	the	the	DT
cord-347298-7kqrl3rv	345	14	human	human	JJ
cord-347298-7kqrl3rv	345	15	testis	testis	NN
cord-347298-7kqrl3rv	345	16	as	as	RB
cord-347298-7kqrl3rv	345	17	well	well	RB
cord-347298-7kqrl3rv	345	18	(	(	-LRB-
cord-347298-7kqrl3rv	345	19	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	345	20	,	,	,
cord-347298-7kqrl3rv	345	21	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	345	22	data	datum	NNS
cord-347298-7kqrl3rv	345	23	)	)	-RRB-
cord-347298-7kqrl3rv	345	24	.	.	.
cord-347298-7kqrl3rv	346	1	B	b	NN
cord-347298-7kqrl3rv	346	2	cells	cell	NNS
cord-347298-7kqrl3rv	346	3	are	be	VBP
cord-347298-7kqrl3rv	346	4	not	not	RB
cord-347298-7kqrl3rv	346	5	usually	usually	RB
cord-347298-7kqrl3rv	346	6	observed	observe	VBN
cord-347298-7kqrl3rv	346	7	in	in	IN
cord-347298-7kqrl3rv	346	8	normal	normal	JJ
cord-347298-7kqrl3rv	346	9	tissues	tissue	NNS
cord-347298-7kqrl3rv	346	10	,	,	,
cord-347298-7kqrl3rv	346	11	and	and	CC
cord-347298-7kqrl3rv	346	12	this	this	DT
cord-347298-7kqrl3rv	346	13	includes	include	VBZ
cord-347298-7kqrl3rv	346	14	the	the	DT
cord-347298-7kqrl3rv	346	15	testis	testis	NN
cord-347298-7kqrl3rv	346	16	.	.	.
cord-347298-7kqrl3rv	347	1	In	in	IN
cord-347298-7kqrl3rv	347	2	the	the	DT
cord-347298-7kqrl3rv	347	3	rat	rat	NN
cord-347298-7kqrl3rv	347	4	,	,	,
cord-347298-7kqrl3rv	347	5	many	many	JJ
cord-347298-7kqrl3rv	347	6	T	t	NN
cord-347298-7kqrl3rv	347	7	cells	cell	NNS
cord-347298-7kqrl3rv	347	8	possess	possess	VBP
cord-347298-7kqrl3rv	347	9	a	a	DT
cord-347298-7kqrl3rv	347	10	memory	memory	NN
cord-347298-7kqrl3rv	347	11	phenotype	phenotype	NN
cord-347298-7kqrl3rv	347	12	,	,	,
cord-347298-7kqrl3rv	347	13	as	as	IN
cord-347298-7kqrl3rv	347	14	would	would	MD
cord-347298-7kqrl3rv	347	15	be	be	VB
cord-347298-7kqrl3rv	347	16	expected	expect	VBN
cord-347298-7kqrl3rv	348	1	(	(	-LRB-
cord-347298-7kqrl3rv	348	2	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	348	3	et	et	NNP
cord-347298-7kqrl3rv	348	4	al	al	NNP
cord-347298-7kqrl3rv	348	5	.	.	.
cord-347298-7kqrl3rv	349	1	1998b	1998b	CD
cord-347298-7kqrl3rv	350	1	;	;	:
cord-347298-7kqrl3rv	350	2	Tompkins	Tompkins	NNP
cord-347298-7kqrl3rv	350	3	et	et	NNP
cord-347298-7kqrl3rv	350	4	al	al	NNP
cord-347298-7kqrl3rv	350	5	.	.	NNP
cord-347298-7kqrl3rv	350	6	1998	1998	CD
cord-347298-7kqrl3rv	350	7	)	)	-RRB-
cord-347298-7kqrl3rv	350	8	.	.	.
cord-347298-7kqrl3rv	351	1	Reanalysis	reanalysis	NN
cord-347298-7kqrl3rv	351	2	of	of	IN
cord-347298-7kqrl3rv	351	3	the	the	DT
cord-347298-7kqrl3rv	351	4	data	datum	NNS
cord-347298-7kqrl3rv	351	5	for	for	IN
cord-347298-7kqrl3rv	351	6	individual	individual	JJ
cord-347298-7kqrl3rv	351	7	animals	animal	NNS
cord-347298-7kqrl3rv	351	8	across	across	IN
cord-347298-7kqrl3rv	351	9	several	several	JJ
cord-347298-7kqrl3rv	351	10	studies	study	NNS
cord-347298-7kqrl3rv	351	11	suggests	suggest	VBZ
cord-347298-7kqrl3rv	351	12	that	that	IN
cord-347298-7kqrl3rv	351	13	their	-PRON-	PRP$
cord-347298-7kqrl3rv	351	14	numbers	number	NNS
cord-347298-7kqrl3rv	351	15	tend	tend	VBP
cord-347298-7kqrl3rv	351	16	to	to	TO
cord-347298-7kqrl3rv	351	17	be	be	VB
cord-347298-7kqrl3rv	351	18	proportional	proportional	JJ
cord-347298-7kqrl3rv	351	19	to	to	IN
cord-347298-7kqrl3rv	351	20	the	the	DT
cord-347298-7kqrl3rv	351	21	numbers	number	NNS
cord-347298-7kqrl3rv	351	22	of	of	IN
cord-347298-7kqrl3rv	351	23	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	351	24	,	,	,
cord-347298-7kqrl3rv	351	25	but	but	CC
cord-347298-7kqrl3rv	351	26	gradually	gradually	RB
cord-347298-7kqrl3rv	351	27	increase	increase	VB
cord-347298-7kqrl3rv	351	28	with	with	IN
cord-347298-7kqrl3rv	351	29	the	the	DT
cord-347298-7kqrl3rv	351	30	age	age	NN
cord-347298-7kqrl3rv	351	31	of	of	IN
cord-347298-7kqrl3rv	351	32	the	the	DT
cord-347298-7kqrl3rv	351	33	animal	animal	NN
cord-347298-7kqrl3rv	351	34	(	(	-LRB-
cord-347298-7kqrl3rv	351	35	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	351	36	et	et	NNP
cord-347298-7kqrl3rv	351	37	al	al	NNP
cord-347298-7kqrl3rv	351	38	.	.	.
cord-347298-7kqrl3rv	352	1	1998b	1998b	CD
cord-347298-7kqrl3rv	352	2	;	;	:
cord-347298-7kqrl3rv	352	3	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	352	4	and	and	CC
cord-347298-7kqrl3rv	352	5	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	352	6	2000	2000	CD
cord-347298-7kqrl3rv	352	7	;	;	:
cord-347298-7kqrl3rv	352	8	Wang	Wang	NNP
cord-347298-7kqrl3rv	352	9	et	et	NNP
cord-347298-7kqrl3rv	352	10	al	al	NNP
cord-347298-7kqrl3rv	352	11	.	.	.
cord-347298-7kqrl3rv	352	12	1994	1994	CD
cord-347298-7kqrl3rv	352	13	)	)	-RRB-
cord-347298-7kqrl3rv	352	14	.	.	.
cord-347298-7kqrl3rv	353	1	Among	among	IN
cord-347298-7kqrl3rv	353	2	the	the	DT
cord-347298-7kqrl3rv	353	3	T	T	NNP
cord-347298-7kqrl3rv	353	4	cells	cell	NNS
cord-347298-7kqrl3rv	353	5	of	of	IN
cord-347298-7kqrl3rv	353	6	the	the	DT
cord-347298-7kqrl3rv	353	7	testis	testis	NN
cord-347298-7kqrl3rv	353	8	,	,	,
cord-347298-7kqrl3rv	353	9	there	there	EX
cord-347298-7kqrl3rv	353	10	is	be	VBZ
cord-347298-7kqrl3rv	353	11	a	a	DT
cord-347298-7kqrl3rv	353	12	strong	strong	JJ
cord-347298-7kqrl3rv	353	13	bias	bias	NN
cord-347298-7kqrl3rv	353	14	toward	toward	IN
cord-347298-7kqrl3rv	353	15	the	the	DT
cord-347298-7kqrl3rv	353	16	CD8	CD8	NNP
cord-347298-7kqrl3rv	353	17	þ	þ	NNP
cord-347298-7kqrl3rv	353	18	(	(	-LRB-
cord-347298-7kqrl3rv	353	19	i.e.	i.e.	FW
cord-347298-7kqrl3rv	353	20	,	,	,
cord-347298-7kqrl3rv	353	21	MHC	MHC	NNP
cord-347298-7kqrl3rv	353	22	class	class	NN
cord-347298-7kqrl3rv	353	23	I	-PRON-	PRP
cord-347298-7kqrl3rv	353	24	restricted	restrict	VBD
cord-347298-7kqrl3rv	353	25	,	,	,
cord-347298-7kqrl3rv	353	26	largely	largely	RB
cord-347298-7kqrl3rv	353	27	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	353	28	)	)	-RRB-
cord-347298-7kqrl3rv	353	29	subset	subset	JJ
cord-347298-7kqrl3rv	354	1	(	(	-LRB-
cord-347298-7kqrl3rv	354	2	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	354	3	et	et	NNP
cord-347298-7kqrl3rv	354	4	al	al	NNP
cord-347298-7kqrl3rv	354	5	.	.	.
cord-347298-7kqrl3rv	355	1	1998b	1998b	CD
cord-347298-7kqrl3rv	356	1	;	;	:
cord-347298-7kqrl3rv	356	2	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	356	3	and	and	CC
cord-347298-7kqrl3rv	356	4	Niemi	Niemi	NNP
cord-347298-7kqrl3rv	356	5	1987	1987	CD
cord-347298-7kqrl3rv	356	6	;	;	:
cord-347298-7kqrl3rv	356	7	Ritchie	Ritchie	NNP
cord-347298-7kqrl3rv	356	8	et	et	NNP
cord-347298-7kqrl3rv	356	9	al	al	NNP
cord-347298-7kqrl3rv	356	10	.	.	.
cord-347298-7kqrl3rv	356	11	1984	1984	CD
cord-347298-7kqrl3rv	356	12	;	;	:
cord-347298-7kqrl3rv	356	13	Tompkins	Tompkins	NNP
cord-347298-7kqrl3rv	356	14	et	et	NNP
cord-347298-7kqrl3rv	356	15	al	al	NNP
cord-347298-7kqrl3rv	356	16	.	.	.
cord-347298-7kqrl3rv	357	1	1998	1998	CD
cord-347298-7kqrl3rv	357	2	;	;	:
cord-347298-7kqrl3rv	357	3	Wang	Wang	NNP
cord-347298-7kqrl3rv	357	4	et	et	NNP
cord-347298-7kqrl3rv	357	5	al	al	NNP
cord-347298-7kqrl3rv	357	6	.	.	.
cord-347298-7kqrl3rv	357	7	1994	1994	CD
cord-347298-7kqrl3rv	357	8	)	)	-RRB-
cord-347298-7kqrl3rv	357	9	.	.	.
cord-347298-7kqrl3rv	358	1	The	the	DT
cord-347298-7kqrl3rv	358	2	prominence	prominence	NN
cord-347298-7kqrl3rv	358	3	of	of	IN
cord-347298-7kqrl3rv	358	4	NK	NK	NNP
cord-347298-7kqrl3rv	358	5	cell	cell	NN
cord-347298-7kqrl3rv	358	6	subsets	subset	NNS
cord-347298-7kqrl3rv	358	7	in	in	IN
cord-347298-7kqrl3rv	358	8	the	the	DT
cord-347298-7kqrl3rv	358	9	testis	testis	NN
cord-347298-7kqrl3rv	358	10	is	be	VBZ
cord-347298-7kqrl3rv	358	11	also	also	RB
cord-347298-7kqrl3rv	358	12	intriguing	intriguing	JJ
cord-347298-7kqrl3rv	358	13	given	give	VBN
cord-347298-7kqrl3rv	358	14	the	the	DT
cord-347298-7kqrl3rv	358	15	reduced	reduce	VBN
cord-347298-7kqrl3rv	358	16	MHC	MHC	NNP
cord-347298-7kqrl3rv	358	17	class	class	NN
cord-347298-7kqrl3rv	358	18	I	-PRON-	PRP
cord-347298-7kqrl3rv	358	19	antigen	antigen	NN
cord-347298-7kqrl3rv	358	20	expression	expression	NN
cord-347298-7kqrl3rv	358	21	in	in	IN
cord-347298-7kqrl3rv	358	22	the	the	DT
cord-347298-7kqrl3rv	358	23	seminiferous	seminiferous	NNP
cord-347298-7kqrl3rv	358	24	compartment	compartment	NNP
cord-347298-7kqrl3rv	358	25	,	,	,
cord-347298-7kqrl3rv	358	26	which	which	WDT
cord-347298-7kqrl3rv	358	27	would	would	MD
cord-347298-7kqrl3rv	358	28	tend	tend	VB
cord-347298-7kqrl3rv	358	29	to	to	TO
cord-347298-7kqrl3rv	358	30	make	make	VB
cord-347298-7kqrl3rv	358	31	these	these	DT
cord-347298-7kqrl3rv	358	32	cells	cell	NNS
cord-347298-7kqrl3rv	358	33	more	more	RBR
cord-347298-7kqrl3rv	358	34	susceptible	susceptible	JJ
cord-347298-7kqrl3rv	358	35	to	to	IN
cord-347298-7kqrl3rv	358	36	NK	NK	NNP
cord-347298-7kqrl3rv	358	37	cells	cell	NNS
cord-347298-7kqrl3rv	358	38	(	(	-LRB-
cord-347298-7kqrl3rv	358	39	Lanier	Lanier	NNP
cord-347298-7kqrl3rv	358	40	2001	2001	CD
cord-347298-7kqrl3rv	358	41	)	)	-RRB-
cord-347298-7kqrl3rv	358	42	.	.	.
cord-347298-7kqrl3rv	359	1	Consistent	consistent	JJ
cord-347298-7kqrl3rv	359	2	with	with	IN
cord-347298-7kqrl3rv	359	3	the	the	DT
cord-347298-7kqrl3rv	359	4	anti	anti	JJ
cord-347298-7kqrl3rv	359	5	-	-	JJ
cord-347298-7kqrl3rv	359	6	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	359	7	/	/	SYM
cord-347298-7kqrl3rv	359	8	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	359	9	phenotype	phenotype	NN
cord-347298-7kqrl3rv	359	10	of	of	IN
cord-347298-7kqrl3rv	359	11	the	the	DT
cord-347298-7kqrl3rv	359	12	major	major	JJ
cord-347298-7kqrl3rv	359	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	359	14	macrophage	macrophage	NN
cord-347298-7kqrl3rv	359	15	subset	subset	NN
cord-347298-7kqrl3rv	359	16	,	,	,
cord-347298-7kqrl3rv	359	17	T	t	NN
cord-347298-7kqrl3rv	359	18	cells	cell	NNS
cord-347298-7kqrl3rv	359	19	and	and	CC
cord-347298-7kqrl3rv	359	20	NKT	NKT	NNP
cord-347298-7kqrl3rv	359	21	cells	cell	NNS
cord-347298-7kqrl3rv	359	22	in	in	IN
cord-347298-7kqrl3rv	359	23	the	the	DT
cord-347298-7kqrl3rv	359	24	rat	rat	NN
cord-347298-7kqrl3rv	359	25	testis	testis	NN
cord-347298-7kqrl3rv	359	26	constitutively	constitutively	RB
cord-347298-7kqrl3rv	359	27	produce	produce	VBP
cord-347298-7kqrl3rv	359	28	IL10	IL10	NNP
cord-347298-7kqrl3rv	359	29	(	(	-LRB-
cord-347298-7kqrl3rv	359	30	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	359	31	,	,	,
cord-347298-7kqrl3rv	359	32	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	359	33	data	datum	NNS
cord-347298-7kqrl3rv	359	34	)	)	-RRB-
cord-347298-7kqrl3rv	359	35	.	.	.
cord-347298-7kqrl3rv	360	1	While	while	IN
cord-347298-7kqrl3rv	360	2	much	much	JJ
cord-347298-7kqrl3rv	360	3	remains	remain	VBZ
cord-347298-7kqrl3rv	360	4	to	to	TO
cord-347298-7kqrl3rv	360	5	be	be	VB
cord-347298-7kqrl3rv	360	6	discovered	discover	VBN
cord-347298-7kqrl3rv	360	7	,	,	,
cord-347298-7kqrl3rv	360	8	the	the	DT
cord-347298-7kqrl3rv	360	9	existing	exist	VBG
cord-347298-7kqrl3rv	360	10	data	datum	NNS
cord-347298-7kqrl3rv	360	11	concerning	concern	VBG
cord-347298-7kqrl3rv	360	12	the	the	DT
cord-347298-7kqrl3rv	360	13	types	type	NNS
cord-347298-7kqrl3rv	360	14	and	and	CC
cord-347298-7kqrl3rv	360	15	activity	activity	NN
cord-347298-7kqrl3rv	360	16	of	of	IN
cord-347298-7kqrl3rv	360	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	360	18	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	360	19	are	be	VBP
cord-347298-7kqrl3rv	360	20	consistent	consistent	JJ
cord-347298-7kqrl3rv	360	21	with	with	IN
cord-347298-7kqrl3rv	360	22	maintaining	maintain	VBG
cord-347298-7kqrl3rv	360	23	immune	immune	JJ
cord-347298-7kqrl3rv	360	24	privilege	privilege	NN
cord-347298-7kqrl3rv	360	25	(	(	-LRB-
cord-347298-7kqrl3rv	360	26	i.e.	i.e.	FW
cord-347298-7kqrl3rv	360	27	,	,	,
cord-347298-7kqrl3rv	360	28	the	the	DT
cord-347298-7kqrl3rv	360	29	presence	presence	NN
cord-347298-7kqrl3rv	360	30	of	of	IN
cord-347298-7kqrl3rv	360	31	immunoregulatory	immunoregulatory	NNP
cord-347298-7kqrl3rv	360	32	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	360	33	)	)	-RRB-
cord-347298-7kqrl3rv	360	34	and	and	CC
cord-347298-7kqrl3rv	360	35	increased	increase	VBN
cord-347298-7kqrl3rv	360	36	innate	innate	JJ
cord-347298-7kqrl3rv	360	37	immunity	immunity	NN
cord-347298-7kqrl3rv	360	38	(	(	-LRB-
cord-347298-7kqrl3rv	360	39	i.e.	i.e.	FW
cord-347298-7kqrl3rv	360	40	,	,	,
cord-347298-7kqrl3rv	360	41	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	360	42	cell	cell	NN
cord-347298-7kqrl3rv	360	43	activity	activity	NN
cord-347298-7kqrl3rv	360	44	)	)	-RRB-
cord-347298-7kqrl3rv	360	45	.	.	.
cord-347298-7kqrl3rv	361	1	Evidence	evidence	NN
cord-347298-7kqrl3rv	361	2	that	that	IN
cord-347298-7kqrl3rv	361	3	PMNs	pmn	NNS
cord-347298-7kqrl3rv	361	4	are	be	VBP
cord-347298-7kqrl3rv	361	5	important	important	JJ
cord-347298-7kqrl3rv	361	6	in	in	IN
cord-347298-7kqrl3rv	361	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	361	8	function	function	NN
cord-347298-7kqrl3rv	361	9	comes	come	VBZ
cord-347298-7kqrl3rv	361	10	from	from	IN
cord-347298-7kqrl3rv	361	11	the	the	DT
cord-347298-7kqrl3rv	361	12	fact	fact	NN
cord-347298-7kqrl3rv	361	13	that	that	IN
cord-347298-7kqrl3rv	361	14	mast	mast	NN
cord-347298-7kqrl3rv	361	15	cells	cell	NNS
cord-347298-7kqrl3rv	361	16	and	and	CC
cord-347298-7kqrl3rv	361	17	eosinophils	eosinophil	NNS
cord-347298-7kqrl3rv	361	18	are	be	VBP
cord-347298-7kqrl3rv	361	19	significant	significant	JJ
cord-347298-7kqrl3rv	361	20	elements	element	NNS
cord-347298-7kqrl3rv	361	21	of	of	IN
cord-347298-7kqrl3rv	361	22	the	the	DT
cord-347298-7kqrl3rv	361	23	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	361	24	tissue	tissue	NN
cord-347298-7kqrl3rv	361	25	in	in	IN
cord-347298-7kqrl3rv	361	26	many	many	JJ
cord-347298-7kqrl3rv	361	27	species	specie	NNS
cord-347298-7kqrl3rv	361	28	.	.	.
cord-347298-7kqrl3rv	362	1	In	in	IN
cord-347298-7kqrl3rv	362	2	the	the	DT
cord-347298-7kqrl3rv	362	3	rat	rat	NN
cord-347298-7kqrl3rv	362	4	,	,	,
cord-347298-7kqrl3rv	362	5	mouse	mouse	NN
cord-347298-7kqrl3rv	362	6	,	,	,
cord-347298-7kqrl3rv	362	7	dog	dog	NN
cord-347298-7kqrl3rv	362	8	,	,	,
cord-347298-7kqrl3rv	362	9	cat	cat	NN
cord-347298-7kqrl3rv	362	10	,	,	,
cord-347298-7kqrl3rv	362	11	bull	bull	NN
cord-347298-7kqrl3rv	362	12	,	,	,
cord-347298-7kqrl3rv	362	13	and	and	CC
cord-347298-7kqrl3rv	362	14	deer	deer	NN
cord-347298-7kqrl3rv	362	15	,	,	,
cord-347298-7kqrl3rv	362	16	both	both	DT
cord-347298-7kqrl3rv	362	17	cell	cell	NN
cord-347298-7kqrl3rv	362	18	types	type	NNS
cord-347298-7kqrl3rv	362	19	are	be	VBP
cord-347298-7kqrl3rv	362	20	largely	largely	RB
cord-347298-7kqrl3rv	362	21	absent	absent	JJ
cord-347298-7kqrl3rv	362	22	from	from	IN
cord-347298-7kqrl3rv	362	23	the	the	DT
cord-347298-7kqrl3rv	362	24	testicular	testicular	JJ
cord-347298-7kqrl3rv	362	25	parenchyma	parenchyma	NN
cord-347298-7kqrl3rv	362	26	,	,	,
cord-347298-7kqrl3rv	362	27	but	but	CC
cord-347298-7kqrl3rv	362	28	are	be	VBP
cord-347298-7kqrl3rv	362	29	associated	associate	VBN
cord-347298-7kqrl3rv	362	30	with	with	IN
cord-347298-7kqrl3rv	362	31	blood	blood	NN
cord-347298-7kqrl3rv	362	32	vessels	vessel	NNS
cord-347298-7kqrl3rv	362	33	in	in	IN
cord-347298-7kqrl3rv	362	34	the	the	DT
cord-347298-7kqrl3rv	362	35	testicular	testicular	JJ
cord-347298-7kqrl3rv	362	36	capsule	capsule	NN
cord-347298-7kqrl3rv	362	37	(	(	-LRB-
cord-347298-7kqrl3rv	362	38	Anton	Anton	NNP
cord-347298-7kqrl3rv	362	39	et	et	NNP
cord-347298-7kqrl3rv	362	40	al	al	NNP
cord-347298-7kqrl3rv	362	41	.	.	NNP
cord-347298-7kqrl3rv	362	42	1998	1998	CD
cord-347298-7kqrl3rv	362	43	)	)	-RRB-
cord-347298-7kqrl3rv	362	44	.	.	.
cord-347298-7kqrl3rv	363	1	Mast	mast	NN
cord-347298-7kqrl3rv	363	2	cells	cell	NNS
cord-347298-7kqrl3rv	363	3	are	be	VBP
cord-347298-7kqrl3rv	363	4	found	find	VBN
cord-347298-7kqrl3rv	363	5	throughout	throughout	IN
cord-347298-7kqrl3rv	363	6	the	the	DT
cord-347298-7kqrl3rv	363	7	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	363	8	tissue	tissue	NN
cord-347298-7kqrl3rv	363	9	in	in	IN
cord-347298-7kqrl3rv	363	10	equine	equine	JJ
cord-347298-7kqrl3rv	363	11	and	and	CC
cord-347298-7kqrl3rv	363	12	human	human	JJ
cord-347298-7kqrl3rv	363	13	testes	testis	NNS
cord-347298-7kqrl3rv	363	14	(	(	-LRB-
cord-347298-7kqrl3rv	363	15	Anton	Anton	NNP
cord-347298-7kqrl3rv	363	16	et	et	NNP
cord-347298-7kqrl3rv	363	17	al	al	NNP
cord-347298-7kqrl3rv	363	18	.	.	.
cord-347298-7kqrl3rv	364	1	1998	1998	CD
cord-347298-7kqrl3rv	364	2	;	;	:
cord-347298-7kqrl3rv	364	3	Nistal	Nistal	NNP
cord-347298-7kqrl3rv	364	4	et	et	FW
cord-347298-7kqrl3rv	364	5	al	al	NNP
cord-347298-7kqrl3rv	364	6	.	.	.
cord-347298-7kqrl3rv	365	1	1984	1984	CD
cord-347298-7kqrl3rv	365	2	;	;	:
cord-347298-7kqrl3rv	365	3	Yamanaka	Yamanaka	NNP
cord-347298-7kqrl3rv	365	4	et	et	NNP
cord-347298-7kqrl3rv	365	5	al	al	NNP
cord-347298-7kqrl3rv	365	6	.	.	.
cord-347298-7kqrl3rv	365	7	2000	2000	CD
cord-347298-7kqrl3rv	365	8	)	)	-RRB-
cord-347298-7kqrl3rv	365	9	,	,	,
cord-347298-7kqrl3rv	365	10	and	and	CC
cord-347298-7kqrl3rv	365	11	both	both	DT
cord-347298-7kqrl3rv	365	12	mast	mast	NN
cord-347298-7kqrl3rv	365	13	cells	cell	NNS
cord-347298-7kqrl3rv	365	14	and	and	CC
cord-347298-7kqrl3rv	365	15	eosinophils	eosinophil	NNS
cord-347298-7kqrl3rv	365	16	are	be	VBP
cord-347298-7kqrl3rv	365	17	present	present	JJ
cord-347298-7kqrl3rv	365	18	in	in	IN
cord-347298-7kqrl3rv	365	19	porcine	porcine	JJ
cord-347298-7kqrl3rv	365	20	species	specie	NNS
cord-347298-7kqrl3rv	366	1	(	(	-LRB-
cord-347298-7kqrl3rv	366	2	Anton	Anton	NNP
cord-347298-7kqrl3rv	366	3	et	et	NNP
cord-347298-7kqrl3rv	366	4	al	al	NNP
cord-347298-7kqrl3rv	366	5	.	.	NNP
cord-347298-7kqrl3rv	366	6	1998	1998	CD
cord-347298-7kqrl3rv	366	7	)	)	-RRB-
cord-347298-7kqrl3rv	366	8	.	.	.
cord-347298-7kqrl3rv	367	1	The	the	DT
cord-347298-7kqrl3rv	367	2	role	role	NN
cord-347298-7kqrl3rv	367	3	of	of	IN
cord-347298-7kqrl3rv	367	4	these	these	DT
cord-347298-7kqrl3rv	367	5	cells	cell	NNS
cord-347298-7kqrl3rv	367	6	in	in	IN
cord-347298-7kqrl3rv	367	7	vascular	vascular	JJ
cord-347298-7kqrl3rv	367	8	control	control	NN
cord-347298-7kqrl3rv	367	9	and	and	CC
cord-347298-7kqrl3rv	367	10	innate	innate	JJ
cord-347298-7kqrl3rv	367	11	immunity	immunity	NN
cord-347298-7kqrl3rv	367	12	can	can	MD
cord-347298-7kqrl3rv	367	13	be	be	VB
cord-347298-7kqrl3rv	367	14	predicted	predict	VBN
cord-347298-7kqrl3rv	367	15	,	,	,
cord-347298-7kqrl3rv	367	16	but	but	CC
cord-347298-7kqrl3rv	367	17	they	-PRON-	PRP
cord-347298-7kqrl3rv	367	18	may	may	MD
cord-347298-7kqrl3rv	367	19	also	also	RB
cord-347298-7kqrl3rv	367	20	play	play	VB
cord-347298-7kqrl3rv	367	21	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	367	22	roles	role	NNS
cord-347298-7kqrl3rv	367	23	,	,	,
cord-347298-7kqrl3rv	367	24	as	as	IN
cord-347298-7kqrl3rv	367	25	mast	mast	NN
cord-347298-7kqrl3rv	367	26	cells	cell	NNS
cord-347298-7kqrl3rv	367	27	do	do	VBP
cord-347298-7kqrl3rv	367	28	in	in	IN
cord-347298-7kqrl3rv	367	29	other	other	JJ
cord-347298-7kqrl3rv	367	30	tissues	tissue	NNS
cord-347298-7kqrl3rv	367	31	.	.	.
cord-347298-7kqrl3rv	368	1	In	in	IN
cord-347298-7kqrl3rv	368	2	humans	human	NNS
cord-347298-7kqrl3rv	368	3	,	,	,
cord-347298-7kqrl3rv	368	4	testicular	testicular	JJ
cord-347298-7kqrl3rv	368	5	mast	mast	JJ
cord-347298-7kqrl3rv	368	6	cell	cell	NN
cord-347298-7kqrl3rv	368	7	numbers	number	NNS
cord-347298-7kqrl3rv	368	8	are	be	VBP
cord-347298-7kqrl3rv	368	9	increased	increase	VBN
cord-347298-7kqrl3rv	368	10	in	in	IN
cord-347298-7kqrl3rv	368	11	infertility	infertility	NN
cord-347298-7kqrl3rv	368	12	(	(	-LRB-
cord-347298-7kqrl3rv	368	13	Meineke	Meineke	NNP
cord-347298-7kqrl3rv	368	14	et	et	NNP
cord-347298-7kqrl3rv	368	15	al	al	NNP
cord-347298-7kqrl3rv	368	16	.	.	.
cord-347298-7kqrl3rv	368	17	2000	2000	CD
cord-347298-7kqrl3rv	368	18	;	;	:
cord-347298-7kqrl3rv	368	19	Nagai	Nagai	NNP
cord-347298-7kqrl3rv	368	20	et	et	NNP
cord-347298-7kqrl3rv	368	21	al	al	NNP
cord-347298-7kqrl3rv	368	22	.	.	.
cord-347298-7kqrl3rv	368	23	1992	1992	CD
cord-347298-7kqrl3rv	368	24	;	;	:
cord-347298-7kqrl3rv	368	25	Yamanaka	Yamanaka	NNP
cord-347298-7kqrl3rv	368	26	et	et	NNP
cord-347298-7kqrl3rv	368	27	al	al	NNP
cord-347298-7kqrl3rv	368	28	.	.	.
cord-347298-7kqrl3rv	368	29	2000	2000	CD
cord-347298-7kqrl3rv	368	30	)	)	-RRB-
cord-347298-7kqrl3rv	368	31	,	,	,
cord-347298-7kqrl3rv	368	32	but	but	CC
cord-347298-7kqrl3rv	368	33	decline	decline	VB
cord-347298-7kqrl3rv	368	34	with	with	IN
cord-347298-7kqrl3rv	368	35	advancing	advance	VBG
cord-347298-7kqrl3rv	368	36	age	age	NN
cord-347298-7kqrl3rv	368	37	(	(	-LRB-
cord-347298-7kqrl3rv	368	38	Nistal	Nistal	NNP
cord-347298-7kqrl3rv	368	39	et	et	FW
cord-347298-7kqrl3rv	368	40	al	al	NNP
cord-347298-7kqrl3rv	368	41	.	.	.
cord-347298-7kqrl3rv	368	42	1984	1984	CD
cord-347298-7kqrl3rv	368	43	)	)	-RRB-
cord-347298-7kqrl3rv	368	44	.	.	.
cord-347298-7kqrl3rv	369	1	The	the	DT
cord-347298-7kqrl3rv	369	2	possibility	possibility	NN
cord-347298-7kqrl3rv	369	3	that	that	IN
cord-347298-7kqrl3rv	369	4	they	-PRON-	PRP
cord-347298-7kqrl3rv	369	5	accumulate	accumulate	VBP
cord-347298-7kqrl3rv	369	6	due	due	IN
cord-347298-7kqrl3rv	369	7	to	to	IN
cord-347298-7kqrl3rv	369	8	past	past	JJ
cord-347298-7kqrl3rv	369	9	immune	immune	JJ
cord-347298-7kqrl3rv	369	10	events	event	NNS
cord-347298-7kqrl3rv	369	11	needs	need	VBZ
cord-347298-7kqrl3rv	369	12	to	to	TO
cord-347298-7kqrl3rv	369	13	be	be	VB
cord-347298-7kqrl3rv	369	14	considered	consider	VBN
cord-347298-7kqrl3rv	369	15	,	,	,
cord-347298-7kqrl3rv	369	16	but	but	CC
cord-347298-7kqrl3rv	369	17	they	-PRON-	PRP
cord-347298-7kqrl3rv	369	18	also	also	RB
cord-347298-7kqrl3rv	369	19	appear	appear	VBP
cord-347298-7kqrl3rv	369	20	to	to	TO
cord-347298-7kqrl3rv	369	21	be	be	VB
cord-347298-7kqrl3rv	369	22	actively	actively	RB
cord-347298-7kqrl3rv	369	23	regulated	regulate	VBN
cord-347298-7kqrl3rv	369	24	.	.	.
cord-347298-7kqrl3rv	370	1	In	in	IN
cord-347298-7kqrl3rv	370	2	the	the	DT
cord-347298-7kqrl3rv	370	3	adult	adult	NN
cord-347298-7kqrl3rv	370	4	rat	rat	NN
cord-347298-7kqrl3rv	370	5	testis	testis	NN
cord-347298-7kqrl3rv	370	6	,	,	,
cord-347298-7kqrl3rv	370	7	mast	mast	NN
cord-347298-7kqrl3rv	370	8	cell	cell	NN
cord-347298-7kqrl3rv	370	9	proliferation	proliferation	NN
cord-347298-7kqrl3rv	370	10	is	be	VBZ
cord-347298-7kqrl3rv	370	11	under	under	IN
cord-347298-7kqrl3rv	370	12	the	the	DT
cord-347298-7kqrl3rv	370	13	control	control	NN
cord-347298-7kqrl3rv	370	14	of	of	IN
cord-347298-7kqrl3rv	370	15	the	the	DT
cord-347298-7kqrl3rv	370	16	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	370	17	cells	cell	NNS
cord-347298-7kqrl3rv	370	18	,	,	,
cord-347298-7kqrl3rv	370	19	suggesting	suggest	VBG
cord-347298-7kqrl3rv	370	20	that	that	IN
cord-347298-7kqrl3rv	370	21	these	these	DT
cord-347298-7kqrl3rv	370	22	cells	cell	NNS
cord-347298-7kqrl3rv	370	23	produce	produce	VBP
cord-347298-7kqrl3rv	370	24	an	an	DT
cord-347298-7kqrl3rv	370	25	inhibitor	inhibitor	NN
cord-347298-7kqrl3rv	370	26	of	of	IN
cord-347298-7kqrl3rv	370	27	mast	mast	JJ
cord-347298-7kqrl3rv	370	28	cell	cell	NN
cord-347298-7kqrl3rv	370	29	activity	activity	NN
cord-347298-7kqrl3rv	370	30	(	(	-LRB-
cord-347298-7kqrl3rv	370	31	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	370	32	et	et	NNP
cord-347298-7kqrl3rv	370	33	al	al	NNP
cord-347298-7kqrl3rv	370	34	.	.	NNP
cord-347298-7kqrl3rv	370	35	1990	1990	CD
cord-347298-7kqrl3rv	370	36	;	;	:
cord-347298-7kqrl3rv	370	37	Wang	Wang	NNP
cord-347298-7kqrl3rv	370	38	et	et	NNP
cord-347298-7kqrl3rv	370	39	al	al	NNP
cord-347298-7kqrl3rv	370	40	.	.	.
cord-347298-7kqrl3rv	370	41	1994	1994	CD
cord-347298-7kqrl3rv	370	42	)	)	-RRB-
cord-347298-7kqrl3rv	370	43	.	.	.
cord-347298-7kqrl3rv	371	1	Neonatal	neonatal	JJ
cord-347298-7kqrl3rv	371	2	estrogen	estrogen	NN
cord-347298-7kqrl3rv	371	3	treatment	treatment	NN
cord-347298-7kqrl3rv	371	4	increases	increase	NNS
cord-347298-7kqrl3rv	371	5	mast	mast	NN
cord-347298-7kqrl3rv	371	6	cell	cell	NN
cord-347298-7kqrl3rv	371	7	numbers	number	NNS
cord-347298-7kqrl3rv	371	8	in	in	IN
cord-347298-7kqrl3rv	371	9	the	the	DT
cord-347298-7kqrl3rv	371	10	rat	rat	NN
cord-347298-7kqrl3rv	371	11	testis	testis	NN
cord-347298-7kqrl3rv	371	12	(	(	-LRB-
cord-347298-7kqrl3rv	371	13	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	371	14	et	et	NNP
cord-347298-7kqrl3rv	371	15	al	al	NNP
cord-347298-7kqrl3rv	371	16	.	.	.
cord-347298-7kqrl3rv	372	1	1989	1989	CD
cord-347298-7kqrl3rv	372	2	(	(	-LRB-
cord-347298-7kqrl3rv	372	3	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	372	4	et	et	NNP
cord-347298-7kqrl3rv	372	5	al	al	NNP
cord-347298-7kqrl3rv	372	6	.	.	NNP
cord-347298-7kqrl3rv	372	7	,	,	,
cord-347298-7kqrl3rv	372	8	1990	1990	CD
cord-347298-7kqrl3rv	372	9	,	,	,
cord-347298-7kqrl3rv	372	10	and	and	CC
cord-347298-7kqrl3rv	372	11	a	a	DT
cord-347298-7kqrl3rv	372	12	relationship	relationship	NN
cord-347298-7kqrl3rv	372	13	with	with	IN
cord-347298-7kqrl3rv	372	14	elevated	elevated	JJ
cord-347298-7kqrl3rv	372	15	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	372	16	cell	cell	NN
cord-347298-7kqrl3rv	372	17	aromatase	aromatase	NN
cord-347298-7kqrl3rv	372	18	activity	activity	NN
cord-347298-7kqrl3rv	372	19	is	be	VBZ
cord-347298-7kqrl3rv	372	20	suggested	suggest	VBN
cord-347298-7kqrl3rv	372	21	by	by	IN
cord-347298-7kqrl3rv	372	22	the	the	DT
cord-347298-7kqrl3rv	372	23	prevalence	prevalence	NN
cord-347298-7kqrl3rv	372	24	of	of	IN
cord-347298-7kqrl3rv	372	25	these	these	DT
cord-347298-7kqrl3rv	372	26	cells	cell	NNS
cord-347298-7kqrl3rv	372	27	in	in	IN
cord-347298-7kqrl3rv	372	28	boar	boar	NN
cord-347298-7kqrl3rv	372	29	and	and	CC
cord-347298-7kqrl3rv	372	30	equine	equine	JJ
cord-347298-7kqrl3rv	372	31	testes	testis	NNS
cord-347298-7kqrl3rv	372	32	(	(	-LRB-
cord-347298-7kqrl3rv	372	33	Eisenhauer	Eisenhauer	NNP
cord-347298-7kqrl3rv	372	34	et	et	NNP
cord-347298-7kqrl3rv	372	35	al	al	NNP
cord-347298-7kqrl3rv	372	36	.	.	.
cord-347298-7kqrl3rv	372	37	1994	1994	CD
cord-347298-7kqrl3rv	372	38	;	;	:
cord-347298-7kqrl3rv	372	39	Raeside	Raeside	NNP
cord-347298-7kqrl3rv	372	40	and	and	CC
cord-347298-7kqrl3rv	372	41	Renaud	Renaud	NNP
cord-347298-7kqrl3rv	372	42	1983	1983	CD
cord-347298-7kqrl3rv	372	43	)	)	-RRB-
cord-347298-7kqrl3rv	372	44	.	.	.
cord-347298-7kqrl3rv	373	1	Neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	373	2	are	be	VBP
cord-347298-7kqrl3rv	373	3	found	find	VBN
cord-347298-7kqrl3rv	373	4	in	in	IN
cord-347298-7kqrl3rv	373	5	the	the	DT
cord-347298-7kqrl3rv	373	6	testis	testis	NN
cord-347298-7kqrl3rv	373	7	only	only	RB
cord-347298-7kqrl3rv	373	8	under	under	IN
cord-347298-7kqrl3rv	373	9	conditions	condition	NNS
cord-347298-7kqrl3rv	373	10	of	of	IN
cord-347298-7kqrl3rv	373	11	testicular	testicular	JJ
cord-347298-7kqrl3rv	373	12	inflammation	inflammation	NN
cord-347298-7kqrl3rv	373	13	or	or	CC
cord-347298-7kqrl3rv	373	14	damage	damage	NN
cord-347298-7kqrl3rv	374	1	(	(	-LRB-
cord-347298-7kqrl3rv	374	2	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	374	3	et	et	NNP
cord-347298-7kqrl3rv	374	4	al	al	NNP
cord-347298-7kqrl3rv	374	5	.	.	.
cord-347298-7kqrl3rv	375	1	2002a	2002a	CD
cord-347298-7kqrl3rv	375	2	;	;	:
cord-347298-7kqrl3rv	376	1	Kohno	Kohno	NNP
cord-347298-7kqrl3rv	376	2	et	et	FW
cord-347298-7kqrl3rv	376	3	al	al	NNP
cord-347298-7kqrl3rv	376	4	.	.	.
cord-347298-7kqrl3rv	377	1	1983a	1983a	CD
cord-347298-7kqrl3rv	378	1	;	;	:
cord-347298-7kqrl3rv	378	2	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	378	3	et	et	NNP
cord-347298-7kqrl3rv	378	4	al	al	NNP
cord-347298-7kqrl3rv	378	5	.	.	NNP
cord-347298-7kqrl3rv	378	6	2000b	2000b	CD
cord-347298-7kqrl3rv	378	7	)	)	-RRB-
cord-347298-7kqrl3rv	378	8	.	.	.
cord-347298-7kqrl3rv	379	1	The	the	DT
cord-347298-7kqrl3rv	379	2	majority	majority	NN
cord-347298-7kqrl3rv	379	3	of	of	IN
cord-347298-7kqrl3rv	379	4	this	this	DT
cord-347298-7kqrl3rv	379	5	chapter	chapter	NN
cord-347298-7kqrl3rv	379	6	deals	deal	VBZ
cord-347298-7kqrl3rv	379	7	with	with	IN
cord-347298-7kqrl3rv	379	8	the	the	DT
cord-347298-7kqrl3rv	379	9	testis	testis	NN
cord-347298-7kqrl3rv	379	10	because	because	IN
cord-347298-7kqrl3rv	379	11	it	-PRON-	PRP
cord-347298-7kqrl3rv	379	12	is	be	VBZ
cord-347298-7kqrl3rv	379	13	the	the	DT
cord-347298-7kqrl3rv	379	14	primary	primary	JJ
cord-347298-7kqrl3rv	379	15	source	source	NN
cord-347298-7kqrl3rv	379	16	of	of	IN
cord-347298-7kqrl3rv	379	17	male	male	JJ
cord-347298-7kqrl3rv	379	18	gametes	gamete	NNS
cord-347298-7kqrl3rv	379	19	and	and	CC
cord-347298-7kqrl3rv	379	20	hormones	hormone	NNS
cord-347298-7kqrl3rv	379	21	,	,	,
cord-347298-7kqrl3rv	379	22	and	and	CC
cord-347298-7kqrl3rv	379	23	damage	damage	NN
cord-347298-7kqrl3rv	379	24	to	to	IN
cord-347298-7kqrl3rv	379	25	this	this	DT
cord-347298-7kqrl3rv	379	26	organ	organ	NN
cord-347298-7kqrl3rv	379	27	tends	tend	VBZ
cord-347298-7kqrl3rv	379	28	to	to	TO
cord-347298-7kqrl3rv	379	29	have	have	VB
cord-347298-7kqrl3rv	379	30	more	more	RBR
cord-347298-7kqrl3rv	379	31	significant	significant	JJ
cord-347298-7kqrl3rv	379	32	consequences	consequence	NNS
cord-347298-7kqrl3rv	379	33	for	for	IN
cord-347298-7kqrl3rv	379	34	fertility	fertility	NN
cord-347298-7kqrl3rv	379	35	.	.	.
cord-347298-7kqrl3rv	380	1	The	the	DT
cord-347298-7kqrl3rv	380	2	remainder	remainder	NN
cord-347298-7kqrl3rv	380	3	of	of	IN
cord-347298-7kqrl3rv	380	4	the	the	DT
cord-347298-7kqrl3rv	380	5	male	male	JJ
cord-347298-7kqrl3rv	380	6	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	380	7	tract	tract	NN
cord-347298-7kqrl3rv	380	8	comprises	comprise	VBZ
cord-347298-7kqrl3rv	380	9	the	the	DT
cord-347298-7kqrl3rv	380	10	epididymis	epididymis	NN
cord-347298-7kqrl3rv	380	11	,	,	,
cord-347298-7kqrl3rv	380	12	vas	vas	NNP
cord-347298-7kqrl3rv	380	13	deferens	deferen	NNS
cord-347298-7kqrl3rv	380	14	,	,	,
cord-347298-7kqrl3rv	380	15	accessory	accessory	NN
cord-347298-7kqrl3rv	380	16	glands	gland	NNS
cord-347298-7kqrl3rv	380	17	,	,	,
cord-347298-7kqrl3rv	380	18	and	and	CC
cord-347298-7kqrl3rv	380	19	the	the	DT
cord-347298-7kqrl3rv	380	20	urethra	urethra	NN
cord-347298-7kqrl3rv	380	21	,	,	,
cord-347298-7kqrl3rv	380	22	which	which	WDT
cord-347298-7kqrl3rv	380	23	are	be	VBP
cord-347298-7kqrl3rv	380	24	all	all	DT
cord-347298-7kqrl3rv	380	25	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	380	26	-	-	HYPH
cord-347298-7kqrl3rv	380	27	lined	line	VBN
cord-347298-7kqrl3rv	380	28	ductal	ductal	JJ
cord-347298-7kqrl3rv	380	29	tissues	tissue	NNS
cord-347298-7kqrl3rv	380	30	of	of	IN
cord-347298-7kqrl3rv	380	31	varying	vary	VBG
cord-347298-7kqrl3rv	380	32	complexity	complexity	NN
cord-347298-7kqrl3rv	380	33	.	.	.
cord-347298-7kqrl3rv	381	1	The	the	DT
cord-347298-7kqrl3rv	381	2	immunology	immunology	NN
cord-347298-7kqrl3rv	381	3	of	of	IN
cord-347298-7kqrl3rv	381	4	these	these	DT
cord-347298-7kqrl3rv	381	5	tissues	tissue	NNS
cord-347298-7kqrl3rv	381	6	appears	appear	VBZ
cord-347298-7kqrl3rv	381	7	to	to	TO
cord-347298-7kqrl3rv	381	8	be	be	VB
cord-347298-7kqrl3rv	381	9	quite	quite	RB
cord-347298-7kqrl3rv	381	10	distinct	distinct	JJ
cord-347298-7kqrl3rv	381	11	from	from	IN
cord-347298-7kqrl3rv	381	12	that	that	DT
cord-347298-7kqrl3rv	381	13	of	of	IN
cord-347298-7kqrl3rv	381	14	the	the	DT
cord-347298-7kqrl3rv	381	15	testis	testis	NN
cord-347298-7kqrl3rv	381	16	.	.	.
cord-347298-7kqrl3rv	382	1	While	while	IN
cord-347298-7kqrl3rv	382	2	it	-PRON-	PRP
cord-347298-7kqrl3rv	382	3	is	be	VBZ
cord-347298-7kqrl3rv	382	4	true	true	JJ
cord-347298-7kqrl3rv	382	5	that	that	IN
cord-347298-7kqrl3rv	382	6	sperm	sperm	NN
cord-347298-7kqrl3rv	382	7	spend	spend	VBP
cord-347298-7kqrl3rv	382	8	relatively	relatively	RB
cord-347298-7kqrl3rv	382	9	little	little	JJ
cord-347298-7kqrl3rv	382	10	time	time	NN
cord-347298-7kqrl3rv	382	11	within	within	IN
cord-347298-7kqrl3rv	382	12	most	most	JJS
cord-347298-7kqrl3rv	382	13	of	of	IN
cord-347298-7kqrl3rv	382	14	these	these	DT
cord-347298-7kqrl3rv	382	15	tissues	tissue	NNS
cord-347298-7kqrl3rv	382	16	,	,	,
cord-347298-7kqrl3rv	382	17	mature	mature	VB
cord-347298-7kqrl3rv	382	18	sperm	sperm	NN
cord-347298-7kqrl3rv	382	19	reside	reside	VB
cord-347298-7kqrl3rv	382	20	within	within	IN
cord-347298-7kqrl3rv	382	21	the	the	DT
cord-347298-7kqrl3rv	382	22	epididymis	epididymis	NN
cord-347298-7kqrl3rv	382	23	for	for	IN
cord-347298-7kqrl3rv	382	24	extended	extended	JJ
cord-347298-7kqrl3rv	382	25	periods	period	NNS
cord-347298-7kqrl3rv	382	26	without	without	IN
cord-347298-7kqrl3rv	382	27	provoking	provoke	VBG
cord-347298-7kqrl3rv	382	28	an	an	DT
cord-347298-7kqrl3rv	382	29	overt	overt	JJ
cord-347298-7kqrl3rv	382	30	immune	immune	JJ
cord-347298-7kqrl3rv	382	31	response	response	NN
cord-347298-7kqrl3rv	382	32	,	,	,
cord-347298-7kqrl3rv	382	33	and	and	CC
cord-347298-7kqrl3rv	382	34	inflammation	inflammation	NN
cord-347298-7kqrl3rv	382	35	and	and	CC
cord-347298-7kqrl3rv	382	36	immune	immune	JJ
cord-347298-7kqrl3rv	382	37	cell	cell	NN
cord-347298-7kqrl3rv	382	38	activity	activity	NN
cord-347298-7kqrl3rv	382	39	can	can	MD
cord-347298-7kqrl3rv	382	40	nonetheless	nonetheless	RB
cord-347298-7kqrl3rv	382	41	have	have	VB
cord-347298-7kqrl3rv	382	42	damaging	damaging	JJ
cord-347298-7kqrl3rv	382	43	effects	effect	NNS
cord-347298-7kqrl3rv	382	44	in	in	IN
cord-347298-7kqrl3rv	382	45	this	this	DT
cord-347298-7kqrl3rv	382	46	organ	organ	NN
cord-347298-7kqrl3rv	382	47	.	.	.
cord-347298-7kqrl3rv	383	1	Significantly	significantly	RB
cord-347298-7kqrl3rv	383	2	,	,	,
cord-347298-7kqrl3rv	383	3	these	these	DT
cord-347298-7kqrl3rv	383	4	tissues	tissue	NNS
cord-347298-7kqrl3rv	383	5	possess	possess	VBP
cord-347298-7kqrl3rv	383	6	normal	normal	JJ
cord-347298-7kqrl3rv	383	7	interepithelial	interepithelial	JJ
cord-347298-7kqrl3rv	383	8	cell	cell	NN
cord-347298-7kqrl3rv	383	9	junctions	junction	NNS
cord-347298-7kqrl3rv	383	10	,	,	,
cord-347298-7kqrl3rv	383	11	but	but	CC
cord-347298-7kqrl3rv	383	12	lack	lack	VBP
cord-347298-7kqrl3rv	383	13	a	a	DT
cord-347298-7kqrl3rv	383	14	completely	completely	RB
cord-347298-7kqrl3rv	383	15	occluding	occlude	VBG
cord-347298-7kqrl3rv	383	16	intercellular	intercellular	JJ
cord-347298-7kqrl3rv	383	17	structure	structure	NN
cord-347298-7kqrl3rv	383	18	analogous	analogous	JJ
cord-347298-7kqrl3rv	383	19	to	to	IN
cord-347298-7kqrl3rv	383	20	the	the	DT
cord-347298-7kqrl3rv	383	21	blood	blood	NN
cord-347298-7kqrl3rv	383	22	-	-	HYPH
cord-347298-7kqrl3rv	383	23	testis	testis	NN
cord-347298-7kqrl3rv	383	24	barrier	barrier	NN
cord-347298-7kqrl3rv	383	25	(	(	-LRB-
cord-347298-7kqrl3rv	383	26	Levy	Levy	NNP
cord-347298-7kqrl3rv	383	27	and	and	CC
cord-347298-7kqrl3rv	383	28	Robaire	Robaire	NNP
cord-347298-7kqrl3rv	383	29	1999	1999	CD
cord-347298-7kqrl3rv	383	30	;	;	:
cord-347298-7kqrl3rv	383	31	Pelletier	Pelletier	NNP
cord-347298-7kqrl3rv	383	32	2001	2001	CD
cord-347298-7kqrl3rv	383	33	)	)	-RRB-
cord-347298-7kqrl3rv	383	34	.	.	.
cord-347298-7kqrl3rv	384	1	Secreted	Secreted	NNP
cord-347298-7kqrl3rv	384	2	IgA	IgA	NNP
cord-347298-7kqrl3rv	384	3	,	,	,
cord-347298-7kqrl3rv	384	4	which	which	WDT
cord-347298-7kqrl3rv	384	5	lacks	lack	VBZ
cord-347298-7kqrl3rv	384	6	the	the	DT
cord-347298-7kqrl3rv	384	7	ability	ability	NN
cord-347298-7kqrl3rv	384	8	to	to	TO
cord-347298-7kqrl3rv	384	9	bind	bind	VB
cord-347298-7kqrl3rv	384	10	complement	complement	NN
cord-347298-7kqrl3rv	384	11	and	and	CC
cord-347298-7kqrl3rv	384	12	possesses	possess	VBZ
cord-347298-7kqrl3rv	384	13	principally	principally	RB
cord-347298-7kqrl3rv	384	14	antiinflammatory	antiinflammatory	JJ
cord-347298-7kqrl3rv	384	15	properties	property	NNS
cord-347298-7kqrl3rv	384	16	as	as	IN
cord-347298-7kqrl3rv	384	17	a	a	DT
cord-347298-7kqrl3rv	384	18	result	result	NN
cord-347298-7kqrl3rv	384	19	,	,	,
cord-347298-7kqrl3rv	384	20	plays	play	VBZ
cord-347298-7kqrl3rv	384	21	an	an	DT
cord-347298-7kqrl3rv	384	22	important	important	JJ
cord-347298-7kqrl3rv	384	23	role	role	NN
cord-347298-7kqrl3rv	384	24	in	in	IN
cord-347298-7kqrl3rv	384	25	the	the	DT
cord-347298-7kqrl3rv	384	26	male	male	JJ
cord-347298-7kqrl3rv	384	27	urogenital	urogenital	JJ
cord-347298-7kqrl3rv	384	28	tract	tract	NN
cord-347298-7kqrl3rv	384	29	(	(	-LRB-
cord-347298-7kqrl3rv	384	30	Clifton	Clifton	NNP
cord-347298-7kqrl3rv	384	31	et	et	NNP
cord-347298-7kqrl3rv	384	32	al	al	NNP
cord-347298-7kqrl3rv	384	33	.	.	NNP
cord-347298-7kqrl3rv	384	34	1992	1992	CD
cord-347298-7kqrl3rv	384	35	;	;	:
cord-347298-7kqrl3rv	384	36	Politch	Politch	NNP
cord-347298-7kqrl3rv	384	37	et	et	NNP
cord-347298-7kqrl3rv	384	38	al	al	NNP
cord-347298-7kqrl3rv	384	39	.	.	NNP
cord-347298-7kqrl3rv	384	40	2007	2007	CD
cord-347298-7kqrl3rv	384	41	;	;	:
cord-347298-7kqrl3rv	384	42	Pudney	Pudney	NNP
cord-347298-7kqrl3rv	384	43	and	and	CC
cord-347298-7kqrl3rv	384	44	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	384	45	1995	1995	CD
cord-347298-7kqrl3rv	384	46	)	)	-RRB-
cord-347298-7kqrl3rv	384	47	,	,	,
cord-347298-7kqrl3rv	384	48	and	and	CC
cord-347298-7kqrl3rv	384	49	the	the	DT
cord-347298-7kqrl3rv	384	50	immunology	immunology	NN
cord-347298-7kqrl3rv	384	51	of	of	IN
cord-347298-7kqrl3rv	384	52	these	these	DT
cord-347298-7kqrl3rv	384	53	organs	organ	NNS
cord-347298-7kqrl3rv	384	54	tends	tend	VBZ
cord-347298-7kqrl3rv	384	55	to	to	TO
cord-347298-7kqrl3rv	384	56	more	more	RBR
cord-347298-7kqrl3rv	384	57	closely	closely	RB
cord-347298-7kqrl3rv	384	58	resemble	resemble	VB
cord-347298-7kqrl3rv	384	59	that	that	DT
cord-347298-7kqrl3rv	384	60	of	of	IN
cord-347298-7kqrl3rv	384	61	other	other	JJ
cord-347298-7kqrl3rv	384	62	elements	element	NNS
cord-347298-7kqrl3rv	384	63	of	of	IN
cord-347298-7kqrl3rv	384	64	the	the	DT
cord-347298-7kqrl3rv	384	65	mucosal	mucosal	JJ
cord-347298-7kqrl3rv	384	66	immune	immune	JJ
cord-347298-7kqrl3rv	384	67	system	system	NN
cord-347298-7kqrl3rv	384	68	,	,	,
cord-347298-7kqrl3rv	384	69	such	such	JJ
cord-347298-7kqrl3rv	384	70	as	as	IN
cord-347298-7kqrl3rv	384	71	the	the	DT
cord-347298-7kqrl3rv	384	72	gastrointestinal	gastrointestinal	JJ
cord-347298-7kqrl3rv	384	73	and	and	CC
cord-347298-7kqrl3rv	384	74	respiratory	respiratory	JJ
cord-347298-7kqrl3rv	384	75	tracts	tract	NNS
cord-347298-7kqrl3rv	384	76	(	(	-LRB-
cord-347298-7kqrl3rv	384	77	Beagley	Beagley	NNP
cord-347298-7kqrl3rv	384	78	et	et	NNP
cord-347298-7kqrl3rv	384	79	al	al	NNP
cord-347298-7kqrl3rv	384	80	.	.	NNP
cord-347298-7kqrl3rv	384	81	1998	1998	CD
cord-347298-7kqrl3rv	384	82	;	;	:
cord-347298-7kqrl3rv	384	83	Clifton	Clifton	NNP
cord-347298-7kqrl3rv	384	84	et	et	NNP
cord-347298-7kqrl3rv	384	85	al	al	NNP
cord-347298-7kqrl3rv	384	86	.	.	.
cord-347298-7kqrl3rv	384	87	1992	1992	CD
cord-347298-7kqrl3rv	385	1	;	;	:
cord-347298-7kqrl3rv	385	2	Mestecky	Mestecky	NNP
cord-347298-7kqrl3rv	385	3	et	et	NNP
cord-347298-7kqrl3rv	385	4	al	al	NNP
cord-347298-7kqrl3rv	385	5	.	.	NNP
cord-347298-7kqrl3rv	385	6	2005	2005	CD
cord-347298-7kqrl3rv	385	7	)	)	-RRB-
cord-347298-7kqrl3rv	385	8	.	.	.
cord-347298-7kqrl3rv	386	1	In	in	IN
cord-347298-7kqrl3rv	386	2	the	the	DT
cord-347298-7kqrl3rv	386	3	absence	absence	NN
cord-347298-7kqrl3rv	386	4	of	of	IN
cord-347298-7kqrl3rv	386	5	the	the	DT
cord-347298-7kqrl3rv	386	6	specialized	specialized	JJ
cord-347298-7kqrl3rv	386	7	mucosal	mucosal	NN
cord-347298-7kqrl3rv	386	8	-	-	HYPH
cord-347298-7kqrl3rv	386	9	associated	associate	VBN
cord-347298-7kqrl3rv	386	10	lymphoepithelial	lymphoepithelial	JJ
cord-347298-7kqrl3rv	386	11	tissue	tissue	NN
cord-347298-7kqrl3rv	386	12	normally	normally	RB
cord-347298-7kqrl3rv	386	13	found	find	VBN
cord-347298-7kqrl3rv	386	14	in	in	IN
cord-347298-7kqrl3rv	386	15	the	the	DT
cord-347298-7kqrl3rv	386	16	gastrointestinal	gastrointestinal	JJ
cord-347298-7kqrl3rv	386	17	and	and	CC
cord-347298-7kqrl3rv	386	18	respiratory	respiratory	JJ
cord-347298-7kqrl3rv	386	19	tracts	tract	NNS
cord-347298-7kqrl3rv	386	20	,	,	,
cord-347298-7kqrl3rv	386	21	it	-PRON-	PRP
cord-347298-7kqrl3rv	386	22	is	be	VBZ
cord-347298-7kqrl3rv	386	23	likely	likely	JJ
cord-347298-7kqrl3rv	386	24	that	that	IN
cord-347298-7kqrl3rv	386	25	the	the	DT
cord-347298-7kqrl3rv	386	26	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	386	27	cells	cell	NNS
cord-347298-7kqrl3rv	386	28	themselves	-PRON-	PRP
cord-347298-7kqrl3rv	386	29	,	,	,
cord-347298-7kqrl3rv	386	30	together	together	RB
cord-347298-7kqrl3rv	386	31	with	with	IN
cord-347298-7kqrl3rv	386	32	the	the	DT
cord-347298-7kqrl3rv	386	33	numerous	numerous	JJ
cord-347298-7kqrl3rv	386	34	intraepithelial	intraepithelial	NN
cord-347298-7kqrl3rv	386	35	and	and	CC
cord-347298-7kqrl3rv	386	36	stromal	stromal	JJ
cord-347298-7kqrl3rv	386	37	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	386	38	and	and	CC
cord-347298-7kqrl3rv	386	39	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	386	40	that	that	WDT
cord-347298-7kqrl3rv	386	41	are	be	VBP
cord-347298-7kqrl3rv	386	42	normally	normally	RB
cord-347298-7kqrl3rv	386	43	found	find	VBN
cord-347298-7kqrl3rv	386	44	within	within	IN
cord-347298-7kqrl3rv	386	45	these	these	DT
cord-347298-7kqrl3rv	386	46	tissues	tissue	NNS
cord-347298-7kqrl3rv	386	47	,	,	,
cord-347298-7kqrl3rv	386	48	mediate	mediate	VB
cord-347298-7kqrl3rv	386	49	local	local	JJ
cord-347298-7kqrl3rv	386	50	immunoregulatory	immunoregulatory	NN
cord-347298-7kqrl3rv	386	51	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	386	52	(	(	-LRB-
cord-347298-7kqrl3rv	386	53	Barratt	Barratt	NNP
cord-347298-7kqrl3rv	386	54	and	and	CC
cord-347298-7kqrl3rv	386	55	Cohen	Cohen	NNP
cord-347298-7kqrl3rv	386	56	1987	1987	CD
cord-347298-7kqrl3rv	386	57	;	;	:
cord-347298-7kqrl3rv	387	1	Dym	Dym	NNP
cord-347298-7kqrl3rv	387	2	and	and	CC
cord-347298-7kqrl3rv	387	3	Romrell	Romrell	NNP
cord-347298-7kqrl3rv	387	4	1975	1975	CD
cord-347298-7kqrl3rv	387	5	;	;	:
cord-347298-7kqrl3rv	387	6	el	el	NNP
cord-347298-7kqrl3rv	387	7	-	-	HYPH
cord-347298-7kqrl3rv	387	8	Demiry	Demiry	NNP
cord-347298-7kqrl3rv	387	9	et	et	FW
cord-347298-7kqrl3rv	387	10	al	al	NNP
cord-347298-7kqrl3rv	387	11	.	.	.
cord-347298-7kqrl3rv	387	12	1985	1985	CD
cord-347298-7kqrl3rv	388	1	;	;	:
cord-347298-7kqrl3rv	388	2	Ritchie	Ritchie	NNP
cord-347298-7kqrl3rv	388	3	et	et	NNP
cord-347298-7kqrl3rv	388	4	al	al	NNP
cord-347298-7kqrl3rv	388	5	.	.	.
cord-347298-7kqrl3rv	388	6	1984	1984	CD
cord-347298-7kqrl3rv	388	7	;	;	.
cord-347298-7kqrl3rv	389	1	Pudney	Pudney	NNP
cord-347298-7kqrl3rv	389	2	and	and	CC
cord-347298-7kqrl3rv	389	3	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	389	4	1995	1995	CD
cord-347298-7kqrl3rv	389	5	;	;	:
cord-347298-7kqrl3rv	389	6	Theyer	Theyer	NNP
cord-347298-7kqrl3rv	389	7	et	et	NNP
cord-347298-7kqrl3rv	389	8	al	al	NNP
cord-347298-7kqrl3rv	389	9	.	.	NNP
cord-347298-7kqrl3rv	389	10	1992	1992	CD
cord-347298-7kqrl3rv	389	11	;	;	:
cord-347298-7kqrl3rv	389	12	Yeung	Yeung	NNP
cord-347298-7kqrl3rv	389	13	et	et	NNP
cord-347298-7kqrl3rv	389	14	al	al	NNP
cord-347298-7kqrl3rv	389	15	.	.	.
cord-347298-7kqrl3rv	389	16	1994	1994	CD
cord-347298-7kqrl3rv	389	17	)	)	-RRB-
cord-347298-7kqrl3rv	389	18	.	.	.
cord-347298-7kqrl3rv	390	1	A	a	DT
cord-347298-7kqrl3rv	390	2	better	well	JJR
cord-347298-7kqrl3rv	390	3	understanding	understanding	NN
cord-347298-7kqrl3rv	390	4	of	of	IN
cord-347298-7kqrl3rv	390	5	the	the	DT
cord-347298-7kqrl3rv	390	6	immunology	immunology	NN
cord-347298-7kqrl3rv	390	7	of	of	IN
cord-347298-7kqrl3rv	390	8	these	these	DT
cord-347298-7kqrl3rv	390	9	tissues	tissue	NNS
cord-347298-7kqrl3rv	390	10	is	be	VBZ
cord-347298-7kqrl3rv	390	11	important	important	JJ
cord-347298-7kqrl3rv	390	12	.	.	.
cord-347298-7kqrl3rv	391	1	Inflammation	inflammation	NN
cord-347298-7kqrl3rv	391	2	,	,	,
cord-347298-7kqrl3rv	391	3	infection	infection	NN
cord-347298-7kqrl3rv	391	4	,	,	,
cord-347298-7kqrl3rv	391	5	and	and	CC
cord-347298-7kqrl3rv	391	6	physical	physical	JJ
cord-347298-7kqrl3rv	391	7	damage	damage	NN
cord-347298-7kqrl3rv	391	8	can	can	MD
cord-347298-7kqrl3rv	391	9	lead	lead	VB
cord-347298-7kqrl3rv	391	10	to	to	IN
cord-347298-7kqrl3rv	391	11	immune	immune	JJ
cord-347298-7kqrl3rv	391	12	reactions	reaction	NNS
cord-347298-7kqrl3rv	391	13	against	against	IN
cord-347298-7kqrl3rv	391	14	the	the	DT
cord-347298-7kqrl3rv	391	15	sperm	sperm	NN
cord-347298-7kqrl3rv	391	16	,	,	,
cord-347298-7kqrl3rv	391	17	which	which	WDT
cord-347298-7kqrl3rv	391	18	in	in	IN
cord-347298-7kqrl3rv	391	19	turn	turn	NN
cord-347298-7kqrl3rv	391	20	may	may	MD
cord-347298-7kqrl3rv	391	21	compromise	compromise	VB
cord-347298-7kqrl3rv	391	22	fertility	fertility	NN
cord-347298-7kqrl3rv	391	23	.	.	.
cord-347298-7kqrl3rv	392	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	392	2	,	,	,
cord-347298-7kqrl3rv	392	3	many	many	JJ
cord-347298-7kqrl3rv	392	4	men	man	NNS
cord-347298-7kqrl3rv	392	5	suffer	suffer	VBP
cord-347298-7kqrl3rv	392	6	from	from	IN
cord-347298-7kqrl3rv	392	7	chronic	chronic	JJ
cord-347298-7kqrl3rv	392	8	pelvic	pelvic	JJ
cord-347298-7kqrl3rv	392	9	pain	pain	NN
cord-347298-7kqrl3rv	392	10	,	,	,
cord-347298-7kqrl3rv	392	11	generally	generally	RB
cord-347298-7kqrl3rv	392	12	manifesting	manifest	VBG
cord-347298-7kqrl3rv	392	13	as	as	IN
cord-347298-7kqrl3rv	392	14	epididymitis	epididymitis	NN
cord-347298-7kqrl3rv	392	15	or	or	CC
cord-347298-7kqrl3rv	392	16	prostatitis	prostatitis	NN
cord-347298-7kqrl3rv	392	17	in	in	IN
cord-347298-7kqrl3rv	392	18	the	the	DT
cord-347298-7kqrl3rv	392	19	absence	absence	NN
cord-347298-7kqrl3rv	392	20	of	of	IN
cord-347298-7kqrl3rv	392	21	a	a	DT
cord-347298-7kqrl3rv	392	22	detectable	detectable	JJ
cord-347298-7kqrl3rv	392	23	infection	infection	NN
cord-347298-7kqrl3rv	392	24	,	,	,
cord-347298-7kqrl3rv	392	25	a	a	DT
cord-347298-7kqrl3rv	392	26	condition	condition	NN
cord-347298-7kqrl3rv	392	27	that	that	WDT
cord-347298-7kqrl3rv	392	28	almost	almost	RB
cord-347298-7kqrl3rv	392	29	certainly	certainly	RB
cord-347298-7kqrl3rv	392	30	involves	involve	VBZ
cord-347298-7kqrl3rv	392	31	chronic	chronic	JJ
cord-347298-7kqrl3rv	392	32	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	392	33	processes	process	NNS
cord-347298-7kqrl3rv	392	34	within	within	IN
cord-347298-7kqrl3rv	392	35	the	the	DT
cord-347298-7kqrl3rv	392	36	male	male	JJ
cord-347298-7kqrl3rv	392	37	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	392	38	tract	tract	NN
cord-347298-7kqrl3rv	392	39	.	.	.
cord-347298-7kqrl3rv	393	1	As	as	IN
cord-347298-7kqrl3rv	393	2	outlined	outline	VBN
cord-347298-7kqrl3rv	393	3	in	in	IN
cord-347298-7kqrl3rv	393	4	the	the	DT
cord-347298-7kqrl3rv	393	5	preceding	precede	VBG
cord-347298-7kqrl3rv	393	6	sections	section	NNS
cord-347298-7kqrl3rv	393	7	,	,	,
cord-347298-7kqrl3rv	393	8	the	the	DT
cord-347298-7kqrl3rv	393	9	testis	testis	NN
cord-347298-7kqrl3rv	393	10	is	be	VBZ
cord-347298-7kqrl3rv	393	11	able	able	JJ
cord-347298-7kqrl3rv	393	12	to	to	TO
cord-347298-7kqrl3rv	393	13	support	support	VB
cord-347298-7kqrl3rv	393	14	immune	immune	JJ
cord-347298-7kqrl3rv	393	15	privilege	privilege	NN
cord-347298-7kqrl3rv	393	16	without	without	IN
cord-347298-7kqrl3rv	393	17	sacrificing	sacrifice	VBG
cord-347298-7kqrl3rv	393	18	immune	immune	JJ
cord-347298-7kqrl3rv	393	19	surveillance	surveillance	NN
cord-347298-7kqrl3rv	393	20	and	and	CC
cord-347298-7kqrl3rv	393	21	protection	protection	NN
cord-347298-7kqrl3rv	393	22	.	.	.
cord-347298-7kqrl3rv	394	1	The	the	DT
cord-347298-7kqrl3rv	394	2	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	394	3	responsible	responsible	JJ
cord-347298-7kqrl3rv	394	4	for	for	IN
cord-347298-7kqrl3rv	394	5	this	this	DT
cord-347298-7kqrl3rv	394	6	immunological	immunological	JJ
cord-347298-7kqrl3rv	394	7	balancing	balancing	NN
cord-347298-7kqrl3rv	394	8	act	act	NN
cord-347298-7kqrl3rv	394	9	are	be	VBP
cord-347298-7kqrl3rv	394	10	still	still	RB
cord-347298-7kqrl3rv	394	11	far	far	RB
cord-347298-7kqrl3rv	394	12	from	from	IN
cord-347298-7kqrl3rv	394	13	understood	understand	VBN
cord-347298-7kqrl3rv	394	14	,	,	,
cord-347298-7kqrl3rv	394	15	but	but	CC
cord-347298-7kqrl3rv	394	16	a	a	DT
cord-347298-7kqrl3rv	394	17	number	number	NN
cord-347298-7kqrl3rv	394	18	of	of	IN
cord-347298-7kqrl3rv	394	19	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	394	20	and	and	CC
cord-347298-7kqrl3rv	394	21	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	394	22	systems	system	NNS
cord-347298-7kqrl3rv	394	23	that	that	WDT
cord-347298-7kqrl3rv	394	24	operate	operate	VBP
cord-347298-7kqrl3rv	394	25	within	within	IN
cord-347298-7kqrl3rv	394	26	the	the	DT
cord-347298-7kqrl3rv	394	27	testis	testis	NN
cord-347298-7kqrl3rv	394	28	have	have	VBP
cord-347298-7kqrl3rv	394	29	been	be	VBN
cord-347298-7kqrl3rv	394	30	investigated	investigate	VBN
cord-347298-7kqrl3rv	394	31	in	in	IN
cord-347298-7kqrl3rv	394	32	varying	vary	VBG
cord-347298-7kqrl3rv	394	33	degrees	degree	NNS
cord-347298-7kqrl3rv	394	34	of	of	IN
cord-347298-7kqrl3rv	394	35	detail	detail	NN
cord-347298-7kqrl3rv	394	36	.	.	.
cord-347298-7kqrl3rv	395	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	395	2	is	be	VBZ
cord-347298-7kqrl3rv	395	3	perhaps	perhaps	RB
cord-347298-7kqrl3rv	395	4	not	not	RB
cord-347298-7kqrl3rv	395	5	very	very	RB
cord-347298-7kqrl3rv	395	6	surprising	surprising	JJ
cord-347298-7kqrl3rv	395	7	that	that	IN
cord-347298-7kqrl3rv	395	8	many	many	JJ
cord-347298-7kqrl3rv	395	9	of	of	IN
cord-347298-7kqrl3rv	395	10	these	these	DT
cord-347298-7kqrl3rv	395	11	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	395	12	systems	system	NNS
cord-347298-7kqrl3rv	395	13	also	also	RB
cord-347298-7kqrl3rv	395	14	impact	impact	VBP
cord-347298-7kqrl3rv	395	15	upon	upon	IN
cord-347298-7kqrl3rv	395	16	normal	normal	JJ
cord-347298-7kqrl3rv	395	17	testis	testis	NN
cord-347298-7kqrl3rv	395	18	physiology	physiology	NN
cord-347298-7kqrl3rv	395	19	,	,	,
cord-347298-7kqrl3rv	395	20	in	in	IN
cord-347298-7kqrl3rv	395	21	addition	addition	NN
cord-347298-7kqrl3rv	395	22	to	to	IN
cord-347298-7kqrl3rv	395	23	their	-PRON-	PRP$
cord-347298-7kqrl3rv	395	24	immunological	immunological	JJ
cord-347298-7kqrl3rv	395	25	and	and	CC
cord-347298-7kqrl3rv	395	26	pathological	pathological	JJ
cord-347298-7kqrl3rv	395	27	roles	role	NNS
cord-347298-7kqrl3rv	395	28	.	.	.
cord-347298-7kqrl3rv	396	1	Given	give	VBN
cord-347298-7kqrl3rv	396	2	that	that	IN
cord-347298-7kqrl3rv	396	3	the	the	DT
cord-347298-7kqrl3rv	396	4	types	type	NNS
cord-347298-7kqrl3rv	396	5	and	and	CC
cord-347298-7kqrl3rv	396	6	properties	property	NNS
cord-347298-7kqrl3rv	396	7	of	of	IN
cord-347298-7kqrl3rv	396	8	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	396	9	found	find	VBN
cord-347298-7kqrl3rv	396	10	within	within	IN
cord-347298-7kqrl3rv	396	11	the	the	DT
cord-347298-7kqrl3rv	396	12	testis	testis	NN
cord-347298-7kqrl3rv	396	13	environment	environment	NN
cord-347298-7kqrl3rv	396	14	are	be	VBP
cord-347298-7kqrl3rv	396	15	consistent	consistent	JJ
cord-347298-7kqrl3rv	396	16	with	with	IN
cord-347298-7kqrl3rv	396	17	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	396	18	and	and	CC
cord-347298-7kqrl3rv	396	19	enhanced	enhance	VBN
cord-347298-7kqrl3rv	396	20	innate	innate	JJ
cord-347298-7kqrl3rv	396	21	immunity	immunity	NN
cord-347298-7kqrl3rv	396	22	,	,	,
cord-347298-7kqrl3rv	396	23	the	the	DT
cord-347298-7kqrl3rv	396	24	focus	focus	NN
cord-347298-7kqrl3rv	396	25	should	should	MD
cord-347298-7kqrl3rv	396	26	be	be	VB
cord-347298-7kqrl3rv	396	27	on	on	IN
cord-347298-7kqrl3rv	396	28	which	which	WDT
cord-347298-7kqrl3rv	396	29	testicular	testicular	JJ
cord-347298-7kqrl3rv	396	30	elements	element	NNS
cord-347298-7kqrl3rv	396	31	are	be	VBP
cord-347298-7kqrl3rv	396	32	involved	involve	VBN
cord-347298-7kqrl3rv	396	33	in	in	IN
cord-347298-7kqrl3rv	396	34	creating	create	VBG
cord-347298-7kqrl3rv	396	35	this	this	DT
cord-347298-7kqrl3rv	396	36	potentially	potentially	RB
cord-347298-7kqrl3rv	396	37	unique	unique	JJ
cord-347298-7kqrl3rv	396	38	immunological	immunological	JJ
cord-347298-7kqrl3rv	396	39	environment	environment	NN
cord-347298-7kqrl3rv	396	40	.	.	.
cord-347298-7kqrl3rv	397	1	Most	Most	JJS
cord-347298-7kqrl3rv	397	2	attention	attention	NN
cord-347298-7kqrl3rv	397	3	in	in	IN
cord-347298-7kqrl3rv	397	4	this	this	DT
cord-347298-7kqrl3rv	397	5	regard	regard	NN
cord-347298-7kqrl3rv	397	6	has	have	VBZ
cord-347298-7kqrl3rv	397	7	been	be	VBN
cord-347298-7kqrl3rv	397	8	directed	direct	VBN
cord-347298-7kqrl3rv	397	9	toward	toward	IN
cord-347298-7kqrl3rv	397	10	the	the	DT
cord-347298-7kqrl3rv	397	11	highly	highly	RB
cord-347298-7kqrl3rv	397	12	versatile	versatile	JJ
cord-347298-7kqrl3rv	397	13	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	397	14	cell	cell	NN
cord-347298-7kqrl3rv	397	15	.	.	.
cord-347298-7kqrl3rv	398	1	Evidence	evidence	NN
cord-347298-7kqrl3rv	398	2	that	that	IN
cord-347298-7kqrl3rv	398	3	the	the	DT
cord-347298-7kqrl3rv	398	4	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	398	5	cell	cell	NN
cord-347298-7kqrl3rv	398	6	possesses	possess	VBZ
cord-347298-7kqrl3rv	398	7	specialized	specialize	VBN
cord-347298-7kqrl3rv	398	8	immunoregulatory	immunoregulatory	NNP
cord-347298-7kqrl3rv	398	9	properties	property	NNS
cord-347298-7kqrl3rv	398	10	comes	come	VBZ
cord-347298-7kqrl3rv	398	11	from	from	IN
cord-347298-7kqrl3rv	398	12	cotransplantation	cotransplantation	NN
cord-347298-7kqrl3rv	398	13	studies	study	NNS
cord-347298-7kqrl3rv	398	14	.	.	.
cord-347298-7kqrl3rv	399	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	399	2	cells	cell	NNS
cord-347298-7kqrl3rv	399	3	from	from	IN
cord-347298-7kqrl3rv	399	4	immature	immature	JJ
cord-347298-7kqrl3rv	399	5	rat	rat	NN
cord-347298-7kqrl3rv	399	6	,	,	,
cord-347298-7kqrl3rv	399	7	murine	murine	NN
cord-347298-7kqrl3rv	399	8	,	,	,
cord-347298-7kqrl3rv	399	9	or	or	CC
cord-347298-7kqrl3rv	399	10	porcine	porcine	JJ
cord-347298-7kqrl3rv	399	11	testes	testis	NNS
cord-347298-7kqrl3rv	399	12	display	display	NN
cord-347298-7kqrl3rv	399	13	extended	extend	VBN
cord-347298-7kqrl3rv	399	14	survival	survival	NN
cord-347298-7kqrl3rv	399	15	as	as	IN
cord-347298-7kqrl3rv	399	16	allografts	allograft	NNS
cord-347298-7kqrl3rv	399	17	or	or	CC
cord-347298-7kqrl3rv	399	18	xenografts	xenograft	NNS
cord-347298-7kqrl3rv	399	19	,	,	,
cord-347298-7kqrl3rv	399	20	and	and	CC
cord-347298-7kqrl3rv	399	21	cotransplantation	cotransplantation	NN
cord-347298-7kqrl3rv	399	22	of	of	IN
cord-347298-7kqrl3rv	399	23	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	399	24	cells	cell	NNS
cord-347298-7kqrl3rv	399	25	or	or	CC
cord-347298-7kqrl3rv	399	26	testis	testis	NN
cord-347298-7kqrl3rv	399	27	cell	cell	NN
cord-347298-7kqrl3rv	399	28	mixtures	mixture	NNS
cord-347298-7kqrl3rv	399	29	containing	contain	VBG
cord-347298-7kqrl3rv	399	30	these	these	DT
cord-347298-7kqrl3rv	399	31	cells	cell	NNS
cord-347298-7kqrl3rv	399	32	confers	confer	VBZ
cord-347298-7kqrl3rv	399	33	increased	increase	VBN
cord-347298-7kqrl3rv	399	34	survival	survival	NN
cord-347298-7kqrl3rv	399	35	on	on	IN
cord-347298-7kqrl3rv	399	36	neural	neural	JJ
cord-347298-7kqrl3rv	399	37	cell	cell	NN
cord-347298-7kqrl3rv	399	38	xenografts	xenograft	NNS
cord-347298-7kqrl3rv	399	39	,	,	,
cord-347298-7kqrl3rv	399	40	and	and	CC
cord-347298-7kqrl3rv	399	41	pancreatic	pancreatic	JJ
cord-347298-7kqrl3rv	399	42	islet	islet	NN
cord-347298-7kqrl3rv	399	43	allografts	allograft	NNS
cord-347298-7kqrl3rv	399	44	and	and	CC
cord-347298-7kqrl3rv	399	45	xenografts	xenograft	NNS
cord-347298-7kqrl3rv	399	46	(	(	-LRB-
cord-347298-7kqrl3rv	399	47	Sanberg	Sanberg	NNP
cord-347298-7kqrl3rv	399	48	et	et	FW
cord-347298-7kqrl3rv	399	49	al	al	NNP
cord-347298-7kqrl3rv	399	50	.	.	.
cord-347298-7kqrl3rv	400	1	1996	1996	CD
cord-347298-7kqrl3rv	400	2	;	;	:
cord-347298-7kqrl3rv	400	3	Selawry	Selawry	NNP
cord-347298-7kqrl3rv	400	4	and	and	CC
cord-347298-7kqrl3rv	400	5	Cameron	Cameron	NNP
cord-347298-7kqrl3rv	400	6	1993	1993	CD
cord-347298-7kqrl3rv	400	7	;	;	:
cord-347298-7kqrl3rv	400	8	Suarez	Suarez	NNP
cord-347298-7kqrl3rv	400	9	-	-	HYPH
cord-347298-7kqrl3rv	400	10	Pinzon	Pinzon	NNP
cord-347298-7kqrl3rv	400	11	et	et	NNP
cord-347298-7kqrl3rv	400	12	al	al	NNP
cord-347298-7kqrl3rv	400	13	.	.	.
cord-347298-7kqrl3rv	400	14	2000	2000	CD
cord-347298-7kqrl3rv	400	15	)	)	-RRB-
cord-347298-7kqrl3rv	400	16	.	.	.
cord-347298-7kqrl3rv	401	1	The	the	DT
cord-347298-7kqrl3rv	401	2	ability	ability	NN
cord-347298-7kqrl3rv	401	3	to	to	TO
cord-347298-7kqrl3rv	401	4	form	form	VB
cord-347298-7kqrl3rv	401	5	a	a	DT
cord-347298-7kqrl3rv	401	6	physical	physical	JJ
cord-347298-7kqrl3rv	401	7	barrier	barrier	NN
cord-347298-7kqrl3rv	401	8	through	through	IN
cord-347298-7kqrl3rv	401	9	inter	inter	JJ
cord-347298-7kqrl3rv	401	10	-	-	JJ
cord-347298-7kqrl3rv	401	11	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	401	12	tight	tight	JJ
cord-347298-7kqrl3rv	401	13	junctions	junction	NNS
cord-347298-7kqrl3rv	401	14	and	and	CC
cord-347298-7kqrl3rv	401	15	the	the	DT
cord-347298-7kqrl3rv	401	16	fact	fact	NN
cord-347298-7kqrl3rv	401	17	that	that	IN
cord-347298-7kqrl3rv	401	18	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	401	19	cells	cell	NNS
cord-347298-7kqrl3rv	401	20	have	have	VBP
cord-347298-7kqrl3rv	401	21	reduced	reduce	VBN
cord-347298-7kqrl3rv	401	22	MHC	MHC	NNP
cord-347298-7kqrl3rv	401	23	expression	expression	NN
cord-347298-7kqrl3rv	401	24	(	(	-LRB-
cord-347298-7kqrl3rv	401	25	Haas	Haas	NNP
cord-347298-7kqrl3rv	401	26	et	et	NNP
cord-347298-7kqrl3rv	401	27	al	al	NNP
cord-347298-7kqrl3rv	401	28	.	.	.
cord-347298-7kqrl3rv	401	29	1988	1988	CD
cord-347298-7kqrl3rv	401	30	;	;	:
cord-347298-7kqrl3rv	401	31	Kohno	Kohno	NNP
cord-347298-7kqrl3rv	401	32	et	et	NNP
cord-347298-7kqrl3rv	401	33	al	al	NNP
cord-347298-7kqrl3rv	401	34	.	.	NNP
cord-347298-7kqrl3rv	401	35	1983b	1983b	CD
cord-347298-7kqrl3rv	401	36	;	;	:
cord-347298-7kqrl3rv	401	37	Sanberg	Sanberg	NNP
cord-347298-7kqrl3rv	401	38	et	et	FW
cord-347298-7kqrl3rv	401	39	al	al	NNP
cord-347298-7kqrl3rv	401	40	.	.	.
cord-347298-7kqrl3rv	401	41	1996	1996	CD
cord-347298-7kqrl3rv	401	42	;	;	:
cord-347298-7kqrl3rv	401	43	Turek	Turek	NNP
cord-347298-7kqrl3rv	401	44	et	et	NNP
cord-347298-7kqrl3rv	401	45	al	al	NNP
cord-347298-7kqrl3rv	401	46	.	.	.
cord-347298-7kqrl3rv	401	47	1996	1996	CD
cord-347298-7kqrl3rv	401	48	)	)	-RRB-
cord-347298-7kqrl3rv	401	49	undoubtedly	undoubtedly	RB
cord-347298-7kqrl3rv	401	50	enhance	enhance	VBP
cord-347298-7kqrl3rv	401	51	their	-PRON-	PRP$
cord-347298-7kqrl3rv	401	52	potential	potential	NN
cord-347298-7kqrl3rv	401	53	to	to	TO
cord-347298-7kqrl3rv	401	54	avoid	avoid	VB
cord-347298-7kqrl3rv	401	55	T	T	NNP
cord-347298-7kqrl3rv	401	56	cell	cell	NN
cord-347298-7kqrl3rv	401	57	activation	activation	NN
cord-347298-7kqrl3rv	401	58	both	both	DT
cord-347298-7kqrl3rv	401	59	in	in	IN
cord-347298-7kqrl3rv	401	60	the	the	DT
cord-347298-7kqrl3rv	401	61	intact	intact	JJ
cord-347298-7kqrl3rv	401	62	testis	testis	NN
cord-347298-7kqrl3rv	401	63	and	and	CC
cord-347298-7kqrl3rv	401	64	in	in	IN
cord-347298-7kqrl3rv	401	65	engraftment	engraftment	NNP
cord-347298-7kqrl3rv	401	66	studies	study	NNS
cord-347298-7kqrl3rv	401	67	.	.	.
cord-347298-7kqrl3rv	402	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	402	2	,	,	,
cord-347298-7kqrl3rv	402	3	a	a	DT
cord-347298-7kqrl3rv	402	4	soluble	soluble	JJ
cord-347298-7kqrl3rv	402	5	form	form	NN
cord-347298-7kqrl3rv	402	6	of	of	IN
cord-347298-7kqrl3rv	402	7	the	the	DT
cord-347298-7kqrl3rv	402	8	nonclassical	nonclassical	JJ
cord-347298-7kqrl3rv	402	9	MHC	MHC	NNP
cord-347298-7kqrl3rv	402	10	class	class	NN
cord-347298-7kqrl3rv	402	11	Ib	Ib	NNP
cord-347298-7kqrl3rv	402	12	molecule	molecule	NN
cord-347298-7kqrl3rv	402	13	HLA	HLA	NNP
cord-347298-7kqrl3rv	402	14	-	-	HYPH
cord-347298-7kqrl3rv	402	15	G	G	NNP
cord-347298-7kqrl3rv	402	16	is	be	VBZ
cord-347298-7kqrl3rv	402	17	produced	produce	VBN
cord-347298-7kqrl3rv	402	18	by	by	IN
cord-347298-7kqrl3rv	402	19	the	the	DT
cord-347298-7kqrl3rv	402	20	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	402	21	cells	cell	NNS
cord-347298-7kqrl3rv	402	22	,	,	,
cord-347298-7kqrl3rv	402	23	as	as	RB
cord-347298-7kqrl3rv	402	24	well	well	RB
cord-347298-7kqrl3rv	402	25	as	as	IN
cord-347298-7kqrl3rv	402	26	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	402	27	,	,	,
cord-347298-7kqrl3rv	402	28	spermatids	spermatids	NNP
cord-347298-7kqrl3rv	402	29	,	,	,
cord-347298-7kqrl3rv	402	30	and	and	CC
cord-347298-7kqrl3rv	402	31	some	some	DT
cord-347298-7kqrl3rv	402	32	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	402	33	cells	cell	NNS
cord-347298-7kqrl3rv	402	34	,	,	,
cord-347298-7kqrl3rv	402	35	in	in	IN
cord-347298-7kqrl3rv	402	36	the	the	DT
cord-347298-7kqrl3rv	402	37	rhesus	rhesus	NNP
cord-347298-7kqrl3rv	402	38	monkey	monkey	NN
cord-347298-7kqrl3rv	402	39	testis	testis	NN
cord-347298-7kqrl3rv	402	40	(	(	-LRB-
cord-347298-7kqrl3rv	402	41	Ryan	Ryan	NNP
cord-347298-7kqrl3rv	402	42	et	et	NNP
cord-347298-7kqrl3rv	402	43	al	al	NNP
cord-347298-7kqrl3rv	402	44	.	.	.
cord-347298-7kqrl3rv	402	45	2002	2002	CD
cord-347298-7kqrl3rv	402	46	)	)	-RRB-
cord-347298-7kqrl3rv	402	47	.	.	.
cord-347298-7kqrl3rv	403	1	This	this	DT
cord-347298-7kqrl3rv	403	2	molecule	molecule	NN
cord-347298-7kqrl3rv	403	3	has	have	VBZ
cord-347298-7kqrl3rv	403	4	been	be	VBN
cord-347298-7kqrl3rv	403	5	implicated	implicate	VBN
cord-347298-7kqrl3rv	403	6	in	in	IN
cord-347298-7kqrl3rv	403	7	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	403	8	of	of	IN
cord-347298-7kqrl3rv	403	9	alloreactive	alloreactive	JJ
cord-347298-7kqrl3rv	403	10	CD8	CD8	NNP
cord-347298-7kqrl3rv	403	11	þ	þ	NNP
cord-347298-7kqrl3rv	403	12	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	403	13	T	t	NN
cord-347298-7kqrl3rv	403	14	cells	cell	NNS
cord-347298-7kqrl3rv	403	15	(	(	-LRB-
cord-347298-7kqrl3rv	403	16	Fournel	Fournel	NNP
cord-347298-7kqrl3rv	403	17	et	et	FW
cord-347298-7kqrl3rv	403	18	al	al	NNP
cord-347298-7kqrl3rv	403	19	.	.	.
cord-347298-7kqrl3rv	403	20	2000	2000	CD
cord-347298-7kqrl3rv	403	21	)	)	-RRB-
cord-347298-7kqrl3rv	403	22	.	.	.
cord-347298-7kqrl3rv	404	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	404	2	cells	cell	NNS
cord-347298-7kqrl3rv	404	3	display	display	VBP
cord-347298-7kqrl3rv	404	4	lymphocytotoxic	lymphocytotoxic	JJ
cord-347298-7kqrl3rv	404	5	activities	activity	NNS
cord-347298-7kqrl3rv	404	6	and	and	CC
cord-347298-7kqrl3rv	404	7	produce	produce	VB
cord-347298-7kqrl3rv	404	8	molecules	molecule	NNS
cord-347298-7kqrl3rv	404	9	with	with	IN
cord-347298-7kqrl3rv	404	10	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	404	11	activity	activity	NN
cord-347298-7kqrl3rv	404	12	,	,	,
cord-347298-7kqrl3rv	404	13	such	such	JJ
cord-347298-7kqrl3rv	404	14	as	as	IN
cord-347298-7kqrl3rv	404	15	TGF1	TGF1	NNP
cord-347298-7kqrl3rv	404	16	(	(	-LRB-
cord-347298-7kqrl3rv	404	17	De	De	NNP
cord-347298-7kqrl3rv	404	18	Cesaris	Cesaris	NNP
cord-347298-7kqrl3rv	404	19	et	et	NNP
cord-347298-7kqrl3rv	404	20	al	al	NNP
cord-347298-7kqrl3rv	404	21	.	.	.
cord-347298-7kqrl3rv	404	22	1992	1992	CD
cord-347298-7kqrl3rv	404	23	;	;	:
cord-347298-7kqrl3rv	404	24	Suarez	Suarez	NNP
cord-347298-7kqrl3rv	404	25	-	-	HYPH
cord-347298-7kqrl3rv	404	26	Pinzon	Pinzon	NNP
cord-347298-7kqrl3rv	404	27	et	et	NNP
cord-347298-7kqrl3rv	404	28	al	al	NNP
cord-347298-7kqrl3rv	404	29	.	.	.
cord-347298-7kqrl3rv	404	30	2000	2000	CD
cord-347298-7kqrl3rv	404	31	;	;	:
cord-347298-7kqrl3rv	404	32	Wyatt	Wyatt	NNP
cord-347298-7kqrl3rv	404	33	et	et	NNP
cord-347298-7kqrl3rv	404	34	al	al	NNP
cord-347298-7kqrl3rv	404	35	.	.	.
cord-347298-7kqrl3rv	405	1	1988	1988	CD
cord-347298-7kqrl3rv	405	2	;	;	:
cord-347298-7kqrl3rv	405	3	Yin	Yin	NNP
cord-347298-7kqrl3rv	405	4	et	et	NNP
cord-347298-7kqrl3rv	405	5	al	al	NNP
cord-347298-7kqrl3rv	405	6	.	.	.
cord-347298-7kqrl3rv	405	7	2006	2006	CD
cord-347298-7kqrl3rv	405	8	)	)	-RRB-
cord-347298-7kqrl3rv	405	9	and	and	CC
cord-347298-7kqrl3rv	405	10	FasL	FasL	NNP
cord-347298-7kqrl3rv	405	11	(	(	-LRB-
cord-347298-7kqrl3rv	405	12	Bellgrau	Bellgrau	NNP
cord-347298-7kqrl3rv	405	13	et	et	NNP
cord-347298-7kqrl3rv	405	14	al	al	NNP
cord-347298-7kqrl3rv	405	15	.	.	.
cord-347298-7kqrl3rv	405	16	1995	1995	CD
cord-347298-7kqrl3rv	406	1	;	;	:
cord-347298-7kqrl3rv	406	2	Yin	Yin	NNP
cord-347298-7kqrl3rv	406	3	et	et	NNP
cord-347298-7kqrl3rv	406	4	al	al	NNP
cord-347298-7kqrl3rv	406	5	.	.	.
cord-347298-7kqrl3rv	406	6	2006	2006	CD
cord-347298-7kqrl3rv	406	7	)	)	-RRB-
cord-347298-7kqrl3rv	406	8	.	.	.
cord-347298-7kqrl3rv	407	1	An	an	DT
cord-347298-7kqrl3rv	407	2	active	active	JJ
cord-347298-7kqrl3rv	407	3	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	407	4	role	role	NN
cord-347298-7kqrl3rv	407	5	has	have	VBZ
cord-347298-7kqrl3rv	407	6	also	also	RB
cord-347298-7kqrl3rv	407	7	been	be	VBN
cord-347298-7kqrl3rv	407	8	suggested	suggest	VBN
cord-347298-7kqrl3rv	407	9	:	:	:
cord-347298-7kqrl3rv	407	10	murine	murine	JJ
cord-347298-7kqrl3rv	407	11	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	407	12	cells	cell	NNS
cord-347298-7kqrl3rv	407	13	treated	treat	VBN
cord-347298-7kqrl3rv	407	14	with	with	IN
cord-347298-7kqrl3rv	407	15	IFN	IFN	NNP
cord-347298-7kqrl3rv	407	16	increase	increase	VB
cord-347298-7kqrl3rv	407	17	expression	expression	NN
cord-347298-7kqrl3rv	407	18	of	of	IN
cord-347298-7kqrl3rv	407	19	MHC	MHC	NNP
cord-347298-7kqrl3rv	407	20	class	class	NN
cord-347298-7kqrl3rv	407	21	II	II	NNP
cord-347298-7kqrl3rv	407	22	molecules	molecule	NNS
cord-347298-7kqrl3rv	407	23	and	and	CC
cord-347298-7kqrl3rv	407	24	the	the	DT
cord-347298-7kqrl3rv	407	25	negative	negative	JJ
cord-347298-7kqrl3rv	407	26	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	407	27	ligand	ligand	NN
cord-347298-7kqrl3rv	407	28	B7-H1	B7-H1	NNP
cord-347298-7kqrl3rv	407	29	,	,	,
cord-347298-7kqrl3rv	407	30	and	and	CC
cord-347298-7kqrl3rv	407	31	stimulate	stimulate	VB
cord-347298-7kqrl3rv	407	32	T	T	NNP
cord-347298-7kqrl3rv	407	33	reg	reg	NN
cord-347298-7kqrl3rv	407	34	numbers	number	NNS
cord-347298-7kqrl3rv	407	35	in	in	IN
cord-347298-7kqrl3rv	407	36	culture	culture	NN
cord-347298-7kqrl3rv	407	37	(	(	-LRB-
cord-347298-7kqrl3rv	407	38	Dal	Dal	NNP
cord-347298-7kqrl3rv	407	39	Secco	Secco	NNP
cord-347298-7kqrl3rv	407	40	et	et	FW
cord-347298-7kqrl3rv	407	41	al	al	NNP
cord-347298-7kqrl3rv	407	42	.	.	NNP
cord-347298-7kqrl3rv	407	43	2008	2008	CD
cord-347298-7kqrl3rv	407	44	)	)	-RRB-
cord-347298-7kqrl3rv	407	45	.	.	.
cord-347298-7kqrl3rv	408	1	The	the	DT
cord-347298-7kqrl3rv	408	2	ability	ability	NN
cord-347298-7kqrl3rv	408	3	of	of	IN
cord-347298-7kqrl3rv	408	4	the	the	DT
cord-347298-7kqrl3rv	408	5	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	408	6	cell	cell	NN
cord-347298-7kqrl3rv	408	7	to	to	TO
cord-347298-7kqrl3rv	408	8	suppress	suppress	VB
cord-347298-7kqrl3rv	408	9	other	other	JJ
cord-347298-7kqrl3rv	408	10	critical	critical	JJ
cord-347298-7kqrl3rv	408	11	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	408	12	events	event	NNS
cord-347298-7kqrl3rv	408	13	through	through	IN
cord-347298-7kqrl3rv	408	14	expression	expression	NN
cord-347298-7kqrl3rv	408	15	of	of	IN
cord-347298-7kqrl3rv	408	16	complement	complement	JJ
cord-347298-7kqrl3rv	408	17	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	408	18	proteins	protein	NNS
cord-347298-7kqrl3rv	408	19	)	)	-RRB-
cord-347298-7kqrl3rv	408	20	and	and	CC
cord-347298-7kqrl3rv	408	21	secretion	secretion	NN
cord-347298-7kqrl3rv	408	22	of	of	IN
cord-347298-7kqrl3rv	408	23	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	408	24	of	of	IN
cord-347298-7kqrl3rv	408	25	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	408	26	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	408	27	activities	activity	NNS
cord-347298-7kqrl3rv	409	1	(	(	-LRB-
cord-347298-7kqrl3rv	409	2	Sipione	Sipione	NNP
cord-347298-7kqrl3rv	409	3	et	et	NNP
cord-347298-7kqrl3rv	409	4	al	al	NNP
cord-347298-7kqrl3rv	409	5	.	.	.
cord-347298-7kqrl3rv	409	6	2006	2006	CD
cord-347298-7kqrl3rv	409	7	)	)	-RRB-
cord-347298-7kqrl3rv	409	8	is	be	VBZ
cord-347298-7kqrl3rv	409	9	also	also	RB
cord-347298-7kqrl3rv	409	10	likely	likely	JJ
cord-347298-7kqrl3rv	409	11	to	to	TO
cord-347298-7kqrl3rv	409	12	be	be	VB
cord-347298-7kqrl3rv	409	13	important	important	JJ
cord-347298-7kqrl3rv	409	14	.	.	.
cord-347298-7kqrl3rv	410	1	Finally	finally	RB
cord-347298-7kqrl3rv	410	2	,	,	,
cord-347298-7kqrl3rv	410	3	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	410	4	cells	cell	NNS
cord-347298-7kqrl3rv	410	5	possess	possess	VBP
cord-347298-7kqrl3rv	410	6	an	an	DT
cord-347298-7kqrl3rv	410	7	enormous	enormous	JJ
cord-347298-7kqrl3rv	410	8	capacity	capacity	NN
cord-347298-7kqrl3rv	410	9	for	for	IN
cord-347298-7kqrl3rv	410	10	phagocytosis	phagocytosis	NN
cord-347298-7kqrl3rv	410	11	of	of	IN
cord-347298-7kqrl3rv	410	12	senescent	senescent	JJ
cord-347298-7kqrl3rv	410	13	cells	cell	NNS
cord-347298-7kqrl3rv	410	14	,	,	,
cord-347298-7kqrl3rv	410	15	cell	cell	NN
cord-347298-7kqrl3rv	410	16	debris	debris	NN
cord-347298-7kqrl3rv	410	17	,	,	,
cord-347298-7kqrl3rv	410	18	and	and	CC
cord-347298-7kqrl3rv	410	19	other	other	JJ
cord-347298-7kqrl3rv	410	20	potentially	potentially	RB
cord-347298-7kqrl3rv	410	21	antigenic	antigenic	JJ
cord-347298-7kqrl3rv	410	22	complexes	complex	NNS
cord-347298-7kqrl3rv	410	23	,	,	,
cord-347298-7kqrl3rv	410	24	which	which	WDT
cord-347298-7kqrl3rv	410	25	could	could	MD
cord-347298-7kqrl3rv	410	26	otherwise	otherwise	RB
cord-347298-7kqrl3rv	410	27	activate	activate	VB
cord-347298-7kqrl3rv	410	28	an	an	DT
cord-347298-7kqrl3rv	410	29	immune	immune	JJ
cord-347298-7kqrl3rv	410	30	response	response	NN
cord-347298-7kqrl3rv	410	31	.	.	.
cord-347298-7kqrl3rv	411	1	Data	datum	NNS
cord-347298-7kqrl3rv	411	2	concerning	concern	VBG
cord-347298-7kqrl3rv	411	3	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	411	4	roles	role	NNS
cord-347298-7kqrl3rv	411	5	of	of	IN
cord-347298-7kqrl3rv	411	6	other	other	JJ
cord-347298-7kqrl3rv	411	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	411	8	cells	cell	NNS
cord-347298-7kqrl3rv	411	9	are	be	VBP
cord-347298-7kqrl3rv	411	10	less	less	RBR
cord-347298-7kqrl3rv	411	11	comprehensive	comprehensive	JJ
cord-347298-7kqrl3rv	411	12	.	.	.
cord-347298-7kqrl3rv	412	1	The	the	DT
cord-347298-7kqrl3rv	412	2	evidence	evidence	NN
cord-347298-7kqrl3rv	412	3	clearly	clearly	RB
cord-347298-7kqrl3rv	412	4	indicates	indicate	VBZ
cord-347298-7kqrl3rv	412	5	a	a	DT
cord-347298-7kqrl3rv	412	6	role	role	NN
cord-347298-7kqrl3rv	412	7	for	for	IN
cord-347298-7kqrl3rv	412	8	Leydig	leydig	NN
cord-347298-7kqrl3rv	412	9	cells	cell	NNS
cord-347298-7kqrl3rv	412	10	in	in	IN
cord-347298-7kqrl3rv	412	11	recruiting	recruit	VBG
cord-347298-7kqrl3rv	412	12	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	412	13	into	into	IN
cord-347298-7kqrl3rv	412	14	the	the	DT
cord-347298-7kqrl3rv	412	15	testis	testis	NN
cord-347298-7kqrl3rv	412	16	,	,	,
cord-347298-7kqrl3rv	412	17	although	although	IN
cord-347298-7kqrl3rv	412	18	testicular	testicular	JJ
cord-347298-7kqrl3rv	412	19	macrophage	macrophage	NN
cord-347298-7kqrl3rv	412	20	function	function	NN
cord-347298-7kqrl3rv	412	21	may	may	MD
cord-347298-7kqrl3rv	412	22	actually	actually	RB
cord-347298-7kqrl3rv	412	23	be	be	VB
cord-347298-7kqrl3rv	412	24	determined	determine	VBN
cord-347298-7kqrl3rv	412	25	by	by	IN
cord-347298-7kqrl3rv	412	26	the	the	DT
cord-347298-7kqrl3rv	412	27	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	412	28	cells	cell	NNS
cord-347298-7kqrl3rv	412	29	(	(	-LRB-
cord-347298-7kqrl3rv	412	30	Duckett	Duckett	NNP
cord-347298-7kqrl3rv	412	31	et	et	FW
cord-347298-7kqrl3rv	412	32	al	al	NNP
cord-347298-7kqrl3rv	412	33	.	.	.
cord-347298-7kqrl3rv	413	1	1997a	1997a	CD
cord-347298-7kqrl3rv	413	2	,	,	,
cord-347298-7kqrl3rv	413	3	b	b	NN
cord-347298-7kqrl3rv	413	4	;	;	:
cord-347298-7kqrl3rv	413	5	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	413	6	et	et	NNP
cord-347298-7kqrl3rv	413	7	al	al	NNP
cord-347298-7kqrl3rv	413	8	.	.	NNP
cord-347298-7kqrl3rv	413	9	1994c	1994c	CD
cord-347298-7kqrl3rv	413	10	;	;	:
cord-347298-7kqrl3rv	413	11	Wang	Wang	NNP
cord-347298-7kqrl3rv	413	12	et	et	NNP
cord-347298-7kqrl3rv	413	13	al	al	NNP
cord-347298-7kqrl3rv	413	14	.	.	.
cord-347298-7kqrl3rv	413	15	1994	1994	CD
cord-347298-7kqrl3rv	413	16	)	)	-RRB-
cord-347298-7kqrl3rv	413	17	.	.	.
cord-347298-7kqrl3rv	414	1	Leydig	leydig	NN
cord-347298-7kqrl3rv	414	2	cells	cell	NNS
cord-347298-7kqrl3rv	414	3	also	also	RB
cord-347298-7kqrl3rv	414	4	produce	produce	VBP
cord-347298-7kqrl3rv	414	5	various	various	JJ
cord-347298-7kqrl3rv	414	6	steroids	steroid	NNS
cord-347298-7kqrl3rv	414	7	,	,	,
cord-347298-7kqrl3rv	414	8	proteins	protein	NNS
cord-347298-7kqrl3rv	414	9	,	,	,
cord-347298-7kqrl3rv	414	10	and	and	CC
cord-347298-7kqrl3rv	414	11	other	other	JJ
cord-347298-7kqrl3rv	414	12	factors	factor	NNS
cord-347298-7kqrl3rv	414	13	with	with	IN
cord-347298-7kqrl3rv	414	14	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	414	15	activity	activity	NN
cord-347298-7kqrl3rv	414	16	,	,	,
cord-347298-7kqrl3rv	414	17	and	and	CC
cord-347298-7kqrl3rv	414	18	inhibit	inhibit	VB
cord-347298-7kqrl3rv	414	19	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	414	20	activity	activity	NN
cord-347298-7kqrl3rv	414	21	in	in	IN
cord-347298-7kqrl3rv	414	22	vitro	vitro	FW
cord-347298-7kqrl3rv	414	23	(	(	-LRB-
cord-347298-7kqrl3rv	415	1	Born	Born	NNP
cord-347298-7kqrl3rv	415	2	and	and	CC
cord-347298-7kqrl3rv	415	3	Wekerle	Wekerle	NNP
cord-347298-7kqrl3rv	415	4	1982	1982	CD
cord-347298-7kqrl3rv	415	5	;	;	:
cord-347298-7kqrl3rv	415	6	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	415	7	et	et	NNP
cord-347298-7kqrl3rv	415	8	al	al	NNP
cord-347298-7kqrl3rv	415	9	.	.	NNP
cord-347298-7kqrl3rv	415	10	1990	1990	CD
cord-347298-7kqrl3rv	415	11	)	)	-RRB-
cord-347298-7kqrl3rv	415	12	.	.	.
cord-347298-7kqrl3rv	416	1	Peritubular	Peritubular	NNP
cord-347298-7kqrl3rv	416	2	cells	cell	NNS
cord-347298-7kqrl3rv	416	3	,	,	,
cord-347298-7kqrl3rv	416	4	like	like	IN
cord-347298-7kqrl3rv	416	5	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	416	6	cells	cell	NNS
cord-347298-7kqrl3rv	416	7	,	,	,
cord-347298-7kqrl3rv	416	8	produce	produce	VBP
cord-347298-7kqrl3rv	416	9	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	416	10	TGF	TGF	NNP
cord-347298-7kqrl3rv	416	11	family	family	NN
cord-347298-7kqrl3rv	416	12	members	member	NNS
cord-347298-7kqrl3rv	416	13	(	(	-LRB-
cord-347298-7kqrl3rv	416	14	Konrad	Konrad	NNP
cord-347298-7kqrl3rv	416	15	et	et	NNP
cord-347298-7kqrl3rv	416	16	al	al	NNP
cord-347298-7kqrl3rv	416	17	.	.	.
cord-347298-7kqrl3rv	416	18	2000	2000	CD
cord-347298-7kqrl3rv	416	19	;	;	:
cord-347298-7kqrl3rv	416	20	Mullaney	Mullaney	NNP
cord-347298-7kqrl3rv	416	21	and	and	CC
cord-347298-7kqrl3rv	416	22	Skinner	Skinner	NNP
cord-347298-7kqrl3rv	416	23	1993	1993	CD
cord-347298-7kqrl3rv	416	24	;	;	:
cord-347298-7kqrl3rv	416	25	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	416	26	et	et	NNP
cord-347298-7kqrl3rv	416	27	al	al	NNP
cord-347298-7kqrl3rv	416	28	.	.	NNP
cord-347298-7kqrl3rv	416	29	2005b	2005b	CD
cord-347298-7kqrl3rv	416	30	)	)	-RRB-
cord-347298-7kqrl3rv	416	31	.	.	.
cord-347298-7kqrl3rv	417	1	The	the	DT
cord-347298-7kqrl3rv	417	2	possibility	possibility	NN
cord-347298-7kqrl3rv	417	3	that	that	IN
cord-347298-7kqrl3rv	417	4	the	the	DT
cord-347298-7kqrl3rv	417	5	germ	germ	NN
cord-347298-7kqrl3rv	417	6	cells	cell	NNS
cord-347298-7kqrl3rv	417	7	themselves	-PRON-	PRP
cord-347298-7kqrl3rv	417	8	have	have	VBP
cord-347298-7kqrl3rv	417	9	a	a	DT
cord-347298-7kqrl3rv	417	10	direct	direct	JJ
cord-347298-7kqrl3rv	417	11	effect	effect	NN
cord-347298-7kqrl3rv	417	12	on	on	IN
cord-347298-7kqrl3rv	417	13	immune	immune	JJ
cord-347298-7kqrl3rv	417	14	cells	cell	NNS
cord-347298-7kqrl3rv	417	15	has	have	VBZ
cord-347298-7kqrl3rv	417	16	also	also	RB
cord-347298-7kqrl3rv	417	17	been	be	VBN
cord-347298-7kqrl3rv	417	18	considered	consider	VBN
cord-347298-7kqrl3rv	417	19	(	(	-LRB-
cord-347298-7kqrl3rv	417	20	Hurtenbach	Hurtenbach	NNP
cord-347298-7kqrl3rv	417	21	and	and	CC
cord-347298-7kqrl3rv	417	22	Shearer	Shearer	NNP
cord-347298-7kqrl3rv	417	23	1982	1982	CD
cord-347298-7kqrl3rv	417	24	)	)	-RRB-
cord-347298-7kqrl3rv	417	25	,	,	,
cord-347298-7kqrl3rv	417	26	although	although	IN
cord-347298-7kqrl3rv	417	27	it	-PRON-	PRP
cord-347298-7kqrl3rv	417	28	seems	seem	VBZ
cord-347298-7kqrl3rv	417	29	more	more	RBR
cord-347298-7kqrl3rv	417	30	likely	likely	JJ
cord-347298-7kqrl3rv	417	31	that	that	IN
cord-347298-7kqrl3rv	417	32	germ	germ	NN
cord-347298-7kqrl3rv	417	33	cells	cell	NNS
cord-347298-7kqrl3rv	417	34	may	may	MD
cord-347298-7kqrl3rv	417	35	influence	influence	VB
cord-347298-7kqrl3rv	417	36	immune	immune	JJ
cord-347298-7kqrl3rv	417	37	responses	response	NNS
cord-347298-7kqrl3rv	417	38	indirectly	indirectly	RB
cord-347298-7kqrl3rv	417	39	by	by	IN
cord-347298-7kqrl3rv	417	40	inducing	induce	VBG
cord-347298-7kqrl3rv	417	41	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	417	42	activities	activity	NNS
cord-347298-7kqrl3rv	417	43	of	of	IN
cord-347298-7kqrl3rv	417	44	the	the	DT
cord-347298-7kqrl3rv	417	45	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	417	46	cells	cell	NNS
cord-347298-7kqrl3rv	417	47	and	and	CC
cord-347298-7kqrl3rv	417	48	other	other	JJ
cord-347298-7kqrl3rv	417	49	somatic	somatic	JJ
cord-347298-7kqrl3rv	417	50	cells	cell	NNS
cord-347298-7kqrl3rv	417	51	.	.	.
cord-347298-7kqrl3rv	418	1	The	the	DT
cord-347298-7kqrl3rv	418	2	relatively	relatively	RB
cord-347298-7kqrl3rv	418	3	recent	recent	JJ
cord-347298-7kqrl3rv	418	4	discovery	discovery	NN
cord-347298-7kqrl3rv	418	5	of	of	IN
cord-347298-7kqrl3rv	418	6	the	the	DT
cord-347298-7kqrl3rv	418	7	TLRs	TLRs	NNPS
cord-347298-7kqrl3rv	418	8	has	have	VBZ
cord-347298-7kqrl3rv	418	9	radically	radically	RB
cord-347298-7kqrl3rv	418	10	expanded	expand	VBN
cord-347298-7kqrl3rv	418	11	our	-PRON-	PRP$
cord-347298-7kqrl3rv	418	12	understanding	understanding	NN
cord-347298-7kqrl3rv	418	13	of	of	IN
cord-347298-7kqrl3rv	418	14	innate	innate	JJ
cord-347298-7kqrl3rv	418	15	immunity	immunity	NN
cord-347298-7kqrl3rv	418	16	and	and	CC
cord-347298-7kqrl3rv	418	17	promises	promise	NNS
cord-347298-7kqrl3rv	418	18	to	to	TO
cord-347298-7kqrl3rv	418	19	do	do	VB
cord-347298-7kqrl3rv	418	20	the	the	DT
cord-347298-7kqrl3rv	418	21	same	same	JJ
cord-347298-7kqrl3rv	418	22	for	for	IN
cord-347298-7kqrl3rv	418	23	testicular	testicular	JJ
cord-347298-7kqrl3rv	418	24	immunology	immunology	NN
cord-347298-7kqrl3rv	418	25	.	.	.
cord-347298-7kqrl3rv	419	1	In	in	IN
cord-347298-7kqrl3rv	419	2	addition	addition	NN
cord-347298-7kqrl3rv	419	3	to	to	IN
cord-347298-7kqrl3rv	419	4	their	-PRON-	PRP$
cord-347298-7kqrl3rv	419	5	predictable	predictable	JJ
cord-347298-7kqrl3rv	419	6	expression	expression	NN
cord-347298-7kqrl3rv	419	7	on	on	IN
cord-347298-7kqrl3rv	419	8	testicular	testicular	JJ
cord-347298-7kqrl3rv	419	9	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	419	10	and	and	CC
cord-347298-7kqrl3rv	419	11	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	419	12	cells	cell	NNS
cord-347298-7kqrl3rv	419	13	,	,	,
cord-347298-7kqrl3rv	419	14	TLR	TLR	NNP
cord-347298-7kqrl3rv	419	15	mRNA	mRNA	NNP
cord-347298-7kqrl3rv	419	16	,	,	,
cord-347298-7kqrl3rv	419	17	protein	protein	NN
cord-347298-7kqrl3rv	419	18	,	,	,
cord-347298-7kqrl3rv	419	19	and/or	and/or	CC
cord-347298-7kqrl3rv	419	20	ligand	ligand	NN
cord-347298-7kqrl3rv	419	21	responses	response	NNS
cord-347298-7kqrl3rv	419	22	have	have	VBP
cord-347298-7kqrl3rv	419	23	been	be	VBN
cord-347298-7kqrl3rv	419	24	described	describe	VBN
cord-347298-7kqrl3rv	419	25	in	in	IN
cord-347298-7kqrl3rv	419	26	several	several	JJ
cord-347298-7kqrl3rv	419	27	other	other	JJ
cord-347298-7kqrl3rv	419	28	testicular	testicular	JJ
cord-347298-7kqrl3rv	419	29	cells	cell	NNS
cord-347298-7kqrl3rv	419	30	.	.	.
cord-347298-7kqrl3rv	420	1	Rat	rat	NN
cord-347298-7kqrl3rv	420	2	and	and	CC
cord-347298-7kqrl3rv	420	3	mouse	mouse	NN
cord-347298-7kqrl3rv	421	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	421	2	cells	cell	NNS
cord-347298-7kqrl3rv	421	3	express	express	VBP
cord-347298-7kqrl3rv	421	4	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	421	5	,	,	,
cord-347298-7kqrl3rv	421	6	3	3	CD
cord-347298-7kqrl3rv	421	7	,	,	,
cord-347298-7kqrl3rv	421	8	4	4	CD
cord-347298-7kqrl3rv	421	9	,	,	,
cord-347298-7kqrl3rv	421	10	and	and	CC
cord-347298-7kqrl3rv	421	11	5	5	LS
cord-347298-7kqrl3rv	421	12	(	(	-LRB-
cord-347298-7kqrl3rv	421	13	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	421	14	et	et	NNP
cord-347298-7kqrl3rv	421	15	al	al	NNP
cord-347298-7kqrl3rv	421	16	.	.	.
cord-347298-7kqrl3rv	422	1	2008	2008	CD
cord-347298-7kqrl3rv	422	2	;	;	:
cord-347298-7kqrl3rv	422	3	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	422	4	et	et	NNP
cord-347298-7kqrl3rv	422	5	al	al	NNP
cord-347298-7kqrl3rv	422	6	.	.	.
cord-347298-7kqrl3rv	423	1	2006	2006	CD
cord-347298-7kqrl3rv	423	2	;	;	:
cord-347298-7kqrl3rv	423	3	Starace	Starace	NNP
cord-347298-7kqrl3rv	423	4	et	et	NNP
cord-347298-7kqrl3rv	423	5	al	al	NNP
cord-347298-7kqrl3rv	423	6	.	.	.
cord-347298-7kqrl3rv	424	1	2008	2008	CD
cord-347298-7kqrl3rv	424	2	;	;	:
cord-347298-7kqrl3rv	424	3	Wu	Wu	NNP
cord-347298-7kqrl3rv	424	4	et	et	NNP
cord-347298-7kqrl3rv	424	5	al	al	NNP
cord-347298-7kqrl3rv	424	6	.	.	NNP
cord-347298-7kqrl3rv	424	7	2008	2008	CD
cord-347298-7kqrl3rv	424	8	)	)	-RRB-
cord-347298-7kqrl3rv	424	9	.	.	.
cord-347298-7kqrl3rv	425	1	TLR1	TLR1	NNP
cord-347298-7kqrl3rv	425	2	,	,	,
cord-347298-7kqrl3rv	425	3	10	10	CD
cord-347298-7kqrl3rv	425	4	,	,	,
cord-347298-7kqrl3rv	425	5	and	and	CC
cord-347298-7kqrl3rv	425	6	11	11	CD
cord-347298-7kqrl3rv	425	7	mRNA	mrna	NN
cord-347298-7kqrl3rv	425	8	expression	expression	NN
cord-347298-7kqrl3rv	425	9	has	have	VBZ
cord-347298-7kqrl3rv	425	10	been	be	VBN
cord-347298-7kqrl3rv	425	11	observed	observe	VBN
cord-347298-7kqrl3rv	425	12	in	in	IN
cord-347298-7kqrl3rv	425	13	rat	rat	NN
cord-347298-7kqrl3rv	425	14	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	425	15	cells	cell	NNS
cord-347298-7kqrl3rv	425	16	(	(	-LRB-
cord-347298-7kqrl3rv	425	17	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	425	18	et	et	NNP
cord-347298-7kqrl3rv	425	19	al	al	NNP
cord-347298-7kqrl3rv	425	20	.	.	NNP
cord-347298-7kqrl3rv	425	21	2008	2008	CD
cord-347298-7kqrl3rv	425	22	)	)	-RRB-
cord-347298-7kqrl3rv	425	23	,	,	,
cord-347298-7kqrl3rv	425	24	and	and	CC
cord-347298-7kqrl3rv	425	25	low	low	JJ
cord-347298-7kqrl3rv	425	26	levels	level	NNS
cord-347298-7kqrl3rv	425	27	of	of	IN
cord-347298-7kqrl3rv	425	28	TLR6	TLR6	NNP
cord-347298-7kqrl3rv	425	29	,	,	,
cord-347298-7kqrl3rv	425	30	7	7	CD
cord-347298-7kqrl3rv	425	31	,	,	,
cord-347298-7kqrl3rv	425	32	and	and	CC
cord-347298-7kqrl3rv	425	33	13	13	CD
cord-347298-7kqrl3rv	425	34	mRNA	mrna	NN
cord-347298-7kqrl3rv	425	35	have	have	VBP
cord-347298-7kqrl3rv	425	36	been	be	VBN
cord-347298-7kqrl3rv	425	37	detected	detect	VBN
cord-347298-7kqrl3rv	425	38	in	in	IN
cord-347298-7kqrl3rv	425	39	mouse	mouse	NN
cord-347298-7kqrl3rv	425	40	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	425	41	cells	cell	NNS
cord-347298-7kqrl3rv	425	42	(	(	-LRB-
cord-347298-7kqrl3rv	425	43	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	425	44	et	et	NNP
cord-347298-7kqrl3rv	425	45	al	al	NNP
cord-347298-7kqrl3rv	425	46	.	.	.
cord-347298-7kqrl3rv	425	47	2006	2006	CD
cord-347298-7kqrl3rv	425	48	;	;	.
cord-347298-7kqrl3rv	426	1	Wu	Wu	NNP
cord-347298-7kqrl3rv	426	2	et	et	NNP
cord-347298-7kqrl3rv	426	3	al	al	NNP
cord-347298-7kqrl3rv	426	4	.	.	NNP
cord-347298-7kqrl3rv	426	5	2008	2008	CD
cord-347298-7kqrl3rv	426	6	)	)	-RRB-
cord-347298-7kqrl3rv	426	7	.	.	.
cord-347298-7kqrl3rv	427	1	In	in	IN
cord-347298-7kqrl3rv	427	2	the	the	DT
cord-347298-7kqrl3rv	427	3	rat	rat	NN
cord-347298-7kqrl3rv	427	4	,	,	,
cord-347298-7kqrl3rv	427	5	germ	germ	NN
cord-347298-7kqrl3rv	427	6	cells	cell	NNS
cord-347298-7kqrl3rv	427	7	also	also	RB
cord-347298-7kqrl3rv	427	8	produce	produce	VBP
cord-347298-7kqrl3rv	427	9	mRNA	mrna	NN
cord-347298-7kqrl3rv	427	10	for	for	IN
cord-347298-7kqrl3rv	427	11	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	427	12	,	,	,
cord-347298-7kqrl3rv	427	13	3	3	CD
cord-347298-7kqrl3rv	427	14	,	,	,
cord-347298-7kqrl3rv	427	15	and	and	CC
cord-347298-7kqrl3rv	427	16	4	4	CD
cord-347298-7kqrl3rv	427	17	in	in	IN
cord-347298-7kqrl3rv	427	18	a	a	DT
cord-347298-7kqrl3rv	427	19	stage	stage	NN
cord-347298-7kqrl3rv	427	20	-	-	HYPH
cord-347298-7kqrl3rv	427	21	specific	specific	JJ
cord-347298-7kqrl3rv	427	22	manner	manner	NN
cord-347298-7kqrl3rv	427	23	,	,	,
cord-347298-7kqrl3rv	427	24	and	and	CC
cord-347298-7kqrl3rv	427	25	the	the	DT
cord-347298-7kqrl3rv	427	26	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	427	27	cells	cell	NNS
cord-347298-7kqrl3rv	427	28	express	express	VBP
cord-347298-7kqrl3rv	427	29	TLR3	TLR3	NNP
cord-347298-7kqrl3rv	427	30	and	and	CC
cord-347298-7kqrl3rv	427	31	11	11	CD
cord-347298-7kqrl3rv	427	32	,	,	,
cord-347298-7kqrl3rv	427	33	along	along	IN
cord-347298-7kqrl3rv	427	34	with	with	IN
cord-347298-7kqrl3rv	427	35	low	low	JJ
cord-347298-7kqrl3rv	427	36	levels	level	NNS
cord-347298-7kqrl3rv	427	37	of	of	IN
cord-347298-7kqrl3rv	427	38	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	427	39	,	,	,
cord-347298-7kqrl3rv	427	40	4	4	CD
cord-347298-7kqrl3rv	427	41	,	,	,
cord-347298-7kqrl3rv	427	42	and	and	CC
cord-347298-7kqrl3rv	427	43	6	6	CD
cord-347298-7kqrl3rv	427	44	(	(	-LRB-
cord-347298-7kqrl3rv	427	45	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	427	46	et	et	NNP
cord-347298-7kqrl3rv	427	47	al	al	NNP
cord-347298-7kqrl3rv	427	48	.	.	NNP
cord-347298-7kqrl3rv	427	49	2008	2008	CD
cord-347298-7kqrl3rv	427	50	)	)	-RRB-
cord-347298-7kqrl3rv	427	51	.	.	.
cord-347298-7kqrl3rv	428	1	Rat	Rat	NNP
cord-347298-7kqrl3rv	428	2	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	428	3	cells	cell	NNS
cord-347298-7kqrl3rv	428	4	express	express	VBP
cord-347298-7kqrl3rv	428	5	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	428	6	mRNA	mrna	NN
cord-347298-7kqrl3rv	428	7	and	and	CC
cord-347298-7kqrl3rv	428	8	low	low	JJ
cord-347298-7kqrl3rv	428	9	levels	level	NNS
cord-347298-7kqrl3rv	428	10	of	of	IN
cord-347298-7kqrl3rv	428	11	TLR10	tlr10	CD
cord-347298-7kqrl3rv	429	1	(	(	-LRB-
cord-347298-7kqrl3rv	429	2	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	429	3	et	et	NNP
cord-347298-7kqrl3rv	429	4	al	al	NNP
cord-347298-7kqrl3rv	429	5	.	.	NNP
cord-347298-7kqrl3rv	429	6	2008	2008	CD
cord-347298-7kqrl3rv	429	7	)	)	-RRB-
cord-347298-7kqrl3rv	429	8	.	.	.
cord-347298-7kqrl3rv	430	1	However	however	RB
cord-347298-7kqrl3rv	430	2	,	,	,
cord-347298-7kqrl3rv	430	3	the	the	DT
cord-347298-7kqrl3rv	430	4	cytoplasmic	cytoplasmic	JJ
cord-347298-7kqrl3rv	430	5	receptors	receptor	NNS
cord-347298-7kqrl3rv	430	6	TLR8	TLR8	NNP
cord-347298-7kqrl3rv	430	7	and	and	CC
cord-347298-7kqrl3rv	430	8	9	9	CD
cord-347298-7kqrl3rv	430	9	have	have	VBP
cord-347298-7kqrl3rv	430	10	yet	yet	RB
cord-347298-7kqrl3rv	430	11	to	to	TO
cord-347298-7kqrl3rv	430	12	be	be	VB
cord-347298-7kqrl3rv	430	13	observed	observe	VBN
cord-347298-7kqrl3rv	430	14	in	in	IN
cord-347298-7kqrl3rv	430	15	any	any	DT
cord-347298-7kqrl3rv	430	16	nonmyeloid	nonmyeloid	NNP
cord-347298-7kqrl3rv	430	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	430	18	cell	cell	NN
cord-347298-7kqrl3rv	430	19	type	type	NN
cord-347298-7kqrl3rv	430	20	.	.	.
cord-347298-7kqrl3rv	431	1	Of	of	IN
cord-347298-7kqrl3rv	431	2	the	the	DT
cord-347298-7kqrl3rv	431	3	other	other	JJ
cord-347298-7kqrl3rv	431	4	pattern	pattern	NN
cord-347298-7kqrl3rv	431	5	-	-	HYPH
cord-347298-7kqrl3rv	431	6	recognition	recognition	NN
cord-347298-7kqrl3rv	431	7	receptors	receptor	NNS
cord-347298-7kqrl3rv	431	8	,	,	,
cord-347298-7kqrl3rv	431	9	Nod1	Nod1	NNP
cord-347298-7kqrl3rv	431	10	mRNA	mRNA	NNP
cord-347298-7kqrl3rv	431	11	has	have	VBZ
cord-347298-7kqrl3rv	431	12	been	be	VBN
cord-347298-7kqrl3rv	431	13	detected	detect	VBN
cord-347298-7kqrl3rv	431	14	in	in	IN
cord-347298-7kqrl3rv	431	15	rat	rat	NN
cord-347298-7kqrl3rv	431	16	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	431	17	cells	cell	NNS
cord-347298-7kqrl3rv	431	18	,	,	,
cord-347298-7kqrl3rv	431	19	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	431	20	cells	cell	NNS
cord-347298-7kqrl3rv	431	21	,	,	,
cord-347298-7kqrl3rv	431	22	and	and	CC
cord-347298-7kqrl3rv	431	23	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	431	24	,	,	,
cord-347298-7kqrl3rv	431	25	while	while	IN
cord-347298-7kqrl3rv	431	26	Nod2	Nod2	NNP
cord-347298-7kqrl3rv	431	27	was	be	VBD
cord-347298-7kqrl3rv	431	28	detected	detect	VBN
cord-347298-7kqrl3rv	431	29	in	in	IN
cord-347298-7kqrl3rv	431	30	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	431	31	only	only	RB
cord-347298-7kqrl3rv	431	32	(	(	-LRB-
cord-347298-7kqrl3rv	431	33	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	431	34	et	et	NNP
cord-347298-7kqrl3rv	431	35	al	al	NNP
cord-347298-7kqrl3rv	431	36	.	.	NNP
cord-347298-7kqrl3rv	431	37	2008	2008	CD
cord-347298-7kqrl3rv	431	38	)	)	-RRB-
cord-347298-7kqrl3rv	431	39	.	.	.
cord-347298-7kqrl3rv	432	1	Expression	expression	NN
cord-347298-7kqrl3rv	432	2	of	of	IN
cord-347298-7kqrl3rv	432	3	TLRs	tlr	NNS
cord-347298-7kqrl3rv	432	4	and	and	CC
cord-347298-7kqrl3rv	432	5	other	other	JJ
cord-347298-7kqrl3rv	432	6	pattern	pattern	NN
cord-347298-7kqrl3rv	432	7	-	-	HYPH
cord-347298-7kqrl3rv	432	8	recognition	recognition	NN
cord-347298-7kqrl3rv	432	9	receptors	receptor	NNS
cord-347298-7kqrl3rv	432	10	in	in	IN
cord-347298-7kqrl3rv	432	11	the	the	DT
cord-347298-7kqrl3rv	432	12	testis	testis	NN
cord-347298-7kqrl3rv	432	13	is	be	VBZ
cord-347298-7kqrl3rv	432	14	obviously	obviously	RB
cord-347298-7kqrl3rv	432	15	important	important	JJ
cord-347298-7kqrl3rv	432	16	for	for	IN
cord-347298-7kqrl3rv	432	17	responses	response	NNS
cord-347298-7kqrl3rv	432	18	toward	toward	IN
cord-347298-7kqrl3rv	432	19	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	432	20	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	432	21	.	.	.
cord-347298-7kqrl3rv	433	1	Infections	infection	NNS
cord-347298-7kqrl3rv	433	2	and	and	CC
cord-347298-7kqrl3rv	433	3	inflammation	inflammation	NN
cord-347298-7kqrl3rv	433	4	,	,	,
cord-347298-7kqrl3rv	433	5	both	both	CC
cord-347298-7kqrl3rv	433	6	systemic	systemic	JJ
cord-347298-7kqrl3rv	433	7	and	and	CC
cord-347298-7kqrl3rv	433	8	localized	localized	JJ
cord-347298-7kqrl3rv	433	9	,	,	,
cord-347298-7kqrl3rv	433	10	have	have	VBP
cord-347298-7kqrl3rv	433	11	negative	negative	JJ
cord-347298-7kqrl3rv	433	12	effects	effect	NNS
cord-347298-7kqrl3rv	433	13	on	on	IN
cord-347298-7kqrl3rv	433	14	testicular	testicular	JJ
cord-347298-7kqrl3rv	433	15	function	function	NN
cord-347298-7kqrl3rv	433	16	,	,	,
cord-347298-7kqrl3rv	433	17	resulting	result	VBG
cord-347298-7kqrl3rv	433	18	in	in	IN
cord-347298-7kqrl3rv	433	19	reduced	reduce	VBN
cord-347298-7kqrl3rv	433	20	androgen	androgen	NN
cord-347298-7kqrl3rv	433	21	production	production	NN
cord-347298-7kqrl3rv	433	22	,	,	,
cord-347298-7kqrl3rv	433	23	lowered	lower	VBD
cord-347298-7kqrl3rv	433	24	sperm	sperm	NN
cord-347298-7kqrl3rv	433	25	counts	count	NNS
cord-347298-7kqrl3rv	433	26	,	,	,
cord-347298-7kqrl3rv	433	27	and	and	CC
cord-347298-7kqrl3rv	433	28	temporary	temporary	JJ
cord-347298-7kqrl3rv	433	29	loss	loss	NN
cord-347298-7kqrl3rv	433	30	of	of	IN
cord-347298-7kqrl3rv	433	31	fertility	fertility	NN
cord-347298-7kqrl3rv	434	1	(	(	-LRB-
cord-347298-7kqrl3rv	434	2	Adamopoulos	Adamopoulos	NNP
cord-347298-7kqrl3rv	434	3	et	et	NNP
cord-347298-7kqrl3rv	434	4	al	al	NNP
cord-347298-7kqrl3rv	434	5	.	.	.
cord-347298-7kqrl3rv	434	6	1978	1978	CD
cord-347298-7kqrl3rv	434	7	;	;	:
cord-347298-7kqrl3rv	434	8	Baker	Baker	NNP
cord-347298-7kqrl3rv	434	9	1998	1998	CD
cord-347298-7kqrl3rv	435	1	;	;	:
cord-347298-7kqrl3rv	435	2	Carlsen	Carlsen	NNP
cord-347298-7kqrl3rv	435	3	et	et	NNP
cord-347298-7kqrl3rv	435	4	al	al	NNP
cord-347298-7kqrl3rv	435	5	.	.	NNP
cord-347298-7kqrl3rv	435	6	2003	2003	CD
cord-347298-7kqrl3rv	435	7	)	)	-RRB-
cord-347298-7kqrl3rv	435	8	.	.	.
cord-347298-7kqrl3rv	436	1	Presumably	presumably	RB
cord-347298-7kqrl3rv	436	2	,	,	,
cord-347298-7kqrl3rv	436	3	TLRs	TLRs	NNP
cord-347298-7kqrl3rv	436	4	expressed	express	VBN
cord-347298-7kqrl3rv	436	5	by	by	IN
cord-347298-7kqrl3rv	436	6	the	the	DT
cord-347298-7kqrl3rv	436	7	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	436	8	cells	cell	NNS
cord-347298-7kqrl3rv	436	9	and	and	CC
cord-347298-7kqrl3rv	436	10	germ	germ	NN
cord-347298-7kqrl3rv	436	11	cells	cell	NNS
cord-347298-7kqrl3rv	436	12	are	be	VBP
cord-347298-7kqrl3rv	436	13	necessary	necessary	JJ
cord-347298-7kqrl3rv	436	14	to	to	TO
cord-347298-7kqrl3rv	436	15	detect	detect	VB
cord-347298-7kqrl3rv	436	16	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	436	17	that	that	WDT
cord-347298-7kqrl3rv	436	18	ascend	ascend	VBP
cord-347298-7kqrl3rv	436	19	the	the	DT
cord-347298-7kqrl3rv	436	20	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	436	21	tract	tract	NN
cord-347298-7kqrl3rv	436	22	and	and	CC
cord-347298-7kqrl3rv	436	23	,	,	,
cord-347298-7kqrl3rv	436	24	as	as	IN
cord-347298-7kqrl3rv	436	25	a	a	DT
cord-347298-7kqrl3rv	436	26	consequence	consequence	NN
cord-347298-7kqrl3rv	436	27	,	,	,
cord-347298-7kqrl3rv	436	28	lie	lie	VB
cord-347298-7kqrl3rv	436	29	behind	behind	IN
cord-347298-7kqrl3rv	436	30	the	the	DT
cord-347298-7kqrl3rv	436	31	blood	blood	NN
cord-347298-7kqrl3rv	436	32	-	-	HYPH
cord-347298-7kqrl3rv	436	33	testis	testis	NN
cord-347298-7kqrl3rv	436	34	barrier	barrier	NN
cord-347298-7kqrl3rv	436	35	.	.	.
cord-347298-7kqrl3rv	437	1	This	this	DT
cord-347298-7kqrl3rv	437	2	expression	expression	NN
cord-347298-7kqrl3rv	437	3	within	within	IN
cord-347298-7kqrl3rv	437	4	the	the	DT
cord-347298-7kqrl3rv	437	5	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	437	6	epithelium	epithelium	NN
cord-347298-7kqrl3rv	437	7	also	also	RB
cord-347298-7kqrl3rv	437	8	suggests	suggest	VBZ
cord-347298-7kqrl3rv	437	9	a	a	DT
cord-347298-7kqrl3rv	437	10	mechanism	mechanism	NN
cord-347298-7kqrl3rv	437	11	whereby	whereby	WRB
cord-347298-7kqrl3rv	437	12	inflammation	inflammation	NN
cord-347298-7kqrl3rv	437	13	can	can	MD
cord-347298-7kqrl3rv	437	14	directly	directly	RB
cord-347298-7kqrl3rv	437	15	inhibit	inhibit	VB
cord-347298-7kqrl3rv	437	16	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	437	17	.	.	.
cord-347298-7kqrl3rv	438	1	Activation	activation	NN
cord-347298-7kqrl3rv	438	2	of	of	IN
cord-347298-7kqrl3rv	438	3	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	438	4	cells	cell	NNS
cord-347298-7kqrl3rv	438	5	by	by	IN
cord-347298-7kqrl3rv	438	6	TLR	TLR	NNP
cord-347298-7kqrl3rv	438	7	ligands	ligand	NNS
cord-347298-7kqrl3rv	438	8	induces	induce	VBZ
cord-347298-7kqrl3rv	438	9	production	production	NN
cord-347298-7kqrl3rv	438	10	of	of	IN
cord-347298-7kqrl3rv	438	11	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	438	12	mediators	mediator	NNS
cord-347298-7kqrl3rv	438	13	,	,	,
cord-347298-7kqrl3rv	438	14	such	such	JJ
cord-347298-7kqrl3rv	438	15	as	as	IN
cord-347298-7kqrl3rv	438	16	IL1	IL1	NNP
cord-347298-7kqrl3rv	438	17	,	,	,
cord-347298-7kqrl3rv	438	18	IL6	IL6	NNP
cord-347298-7kqrl3rv	438	19	,	,	,
cord-347298-7kqrl3rv	438	20	and	and	CC
cord-347298-7kqrl3rv	438	21	NO	no	UH
cord-347298-7kqrl3rv	438	22	,	,	,
cord-347298-7kqrl3rv	438	23	which	which	WDT
cord-347298-7kqrl3rv	438	24	have	have	VBP
cord-347298-7kqrl3rv	438	25	direct	direct	JJ
cord-347298-7kqrl3rv	438	26	effects	effect	NNS
cord-347298-7kqrl3rv	438	27	on	on	IN
cord-347298-7kqrl3rv	438	28	germ	germ	NN
cord-347298-7kqrl3rv	438	29	cell	cell	NN
cord-347298-7kqrl3rv	438	30	development	development	NN
cord-347298-7kqrl3rv	438	31	and	and	CC
cord-347298-7kqrl3rv	438	32	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	438	33	cell	cell	NN
cord-347298-7kqrl3rv	438	34	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	438	35	(	(	-LRB-
cord-347298-7kqrl3rv	438	36	Gérard	Gérard	NNP
cord-347298-7kqrl3rv	438	37	et	et	FW
cord-347298-7kqrl3rv	438	38	al	al	NNP
cord-347298-7kqrl3rv	438	39	.	.	NNP
cord-347298-7kqrl3rv	438	40	1992	1992	CD
cord-347298-7kqrl3rv	438	41	;	;	:
cord-347298-7kqrl3rv	438	42	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	438	43	et	et	NNP
cord-347298-7kqrl3rv	438	44	al	al	NNP
cord-347298-7kqrl3rv	438	45	.	.	.
cord-347298-7kqrl3rv	439	1	1995	1995	CD
cord-347298-7kqrl3rv	440	1	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	440	2	et	et	FW
cord-347298-7kqrl3rv	440	3	al	al	NNP
cord-347298-7kqrl3rv	440	4	.	.	NNP
cord-347298-7kqrl3rv	440	5	,	,	,
cord-347298-7kqrl3rv	441	1	1997	1997	CD
cord-347298-7kqrl3rv	441	2	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	441	3	and	and	CC
cord-347298-7kqrl3rv	441	4	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	441	5	2008	2008	CD
cord-347298-7kqrl3rv	441	6	;	;	:
cord-347298-7kqrl3rv	441	7	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	441	8	et	et	NNP
cord-347298-7kqrl3rv	441	9	al	al	NNP
cord-347298-7kqrl3rv	441	10	.	.	.
cord-347298-7kqrl3rv	442	1	2006	2006	CD
cord-347298-7kqrl3rv	442	2	;	;	:
cord-347298-7kqrl3rv	442	3	Wu	Wu	NNP
cord-347298-7kqrl3rv	442	4	et	et	NNP
cord-347298-7kqrl3rv	442	5	al	al	NNP
cord-347298-7kqrl3rv	442	6	.	.	NNP
cord-347298-7kqrl3rv	442	7	2008	2008	CD
cord-347298-7kqrl3rv	442	8	)	)	-RRB-
cord-347298-7kqrl3rv	442	9	.	.	.
cord-347298-7kqrl3rv	443	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	443	2	,	,	,
cord-347298-7kqrl3rv	443	3	while	while	IN
cord-347298-7kqrl3rv	443	4	inhibition	inhibition	NN
cord-347298-7kqrl3rv	443	5	of	of	IN
cord-347298-7kqrl3rv	443	6	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	443	7	cell	cell	NN
cord-347298-7kqrl3rv	443	8	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	443	9	during	during	IN
cord-347298-7kqrl3rv	443	10	inflammation	inflammation	NN
cord-347298-7kqrl3rv	443	11	may	may	MD
cord-347298-7kqrl3rv	443	12	involve	involve	VB
cord-347298-7kqrl3rv	443	13	indirect	indirect	JJ
cord-347298-7kqrl3rv	443	14	effects	effect	NNS
cord-347298-7kqrl3rv	443	15	at	at	IN
cord-347298-7kqrl3rv	443	16	the	the	DT
cord-347298-7kqrl3rv	443	17	level	level	NN
cord-347298-7kqrl3rv	443	18	of	of	IN
cord-347298-7kqrl3rv	443	19	the	the	DT
cord-347298-7kqrl3rv	443	20	pituitary	pituitary	NN
cord-347298-7kqrl3rv	443	21	,	,	,
cord-347298-7kqrl3rv	443	22	or	or	CC
cord-347298-7kqrl3rv	443	23	the	the	DT
cord-347298-7kqrl3rv	443	24	actions	action	NNS
cord-347298-7kqrl3rv	443	25	of	of	IN
cord-347298-7kqrl3rv	443	26	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	443	27	mediators	mediator	NNS
cord-347298-7kqrl3rv	443	28	produced	produce	VBN
cord-347298-7kqrl3rv	443	29	by	by	IN
cord-347298-7kqrl3rv	443	30	the	the	DT
cord-347298-7kqrl3rv	443	31	testicular	testicular	JJ
cord-347298-7kqrl3rv	443	32	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	443	33	and	and	CC
cord-347298-7kqrl3rv	443	34	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	443	35	cells	cell	NNS
cord-347298-7kqrl3rv	443	36	,	,	,
cord-347298-7kqrl3rv	443	37	there	there	EX
cord-347298-7kqrl3rv	443	38	is	be	VBZ
cord-347298-7kqrl3rv	443	39	evidence	evidence	NN
cord-347298-7kqrl3rv	443	40	that	that	IN
cord-347298-7kqrl3rv	443	41	these	these	DT
cord-347298-7kqrl3rv	443	42	cells	cell	NNS
cord-347298-7kqrl3rv	443	43	can	can	MD
cord-347298-7kqrl3rv	443	44	also	also	RB
cord-347298-7kqrl3rv	443	45	respond	respond	VB
cord-347298-7kqrl3rv	443	46	directly	directly	RB
cord-347298-7kqrl3rv	443	47	to	to	IN
cord-347298-7kqrl3rv	443	48	TLR	TLR	NNP
cord-347298-7kqrl3rv	443	49	ligands	ligand	NNS
cord-347298-7kqrl3rv	443	50	(	(	-LRB-
cord-347298-7kqrl3rv	443	51	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	443	52	et	et	NNP
cord-347298-7kqrl3rv	443	53	al	al	NNP
cord-347298-7kqrl3rv	443	54	.	.	NNP
cord-347298-7kqrl3rv	443	55	2008	2008	CD
cord-347298-7kqrl3rv	443	56	;	;	:
cord-347298-7kqrl3rv	443	57	Xiong	Xiong	NNP
cord-347298-7kqrl3rv	443	58	and	and	CC
cord-347298-7kqrl3rv	443	59	Hales	Hales	NNP
cord-347298-7kqrl3rv	443	60	1993a	1993a	CD
cord-347298-7kqrl3rv	443	61	)	)	-RRB-
cord-347298-7kqrl3rv	443	62	.	.	.
cord-347298-7kqrl3rv	444	1	Although	although	IN
cord-347298-7kqrl3rv	444	2	the	the	DT
cord-347298-7kqrl3rv	444	3	TLRs	tlr	NNS
cord-347298-7kqrl3rv	444	4	have	have	VBP
cord-347298-7kqrl3rv	444	5	evolved	evolve	VBN
cord-347298-7kqrl3rv	444	6	to	to	TO
cord-347298-7kqrl3rv	444	7	recognize	recognize	VB
cord-347298-7kqrl3rv	444	8	pathogen	pathogen	NN
cord-347298-7kqrl3rv	444	9	-	-	HYPH
cord-347298-7kqrl3rv	444	10	derived	derive	VBN
cord-347298-7kqrl3rv	444	11	molecules	molecule	NNS
cord-347298-7kqrl3rv	444	12	,	,	,
cord-347298-7kqrl3rv	444	13	such	such	JJ
cord-347298-7kqrl3rv	444	14	as	as	IN
cord-347298-7kqrl3rv	444	15	LPS	LPS	NNP
cord-347298-7kqrl3rv	444	16	(	(	-LRB-
cord-347298-7kqrl3rv	444	17	TLR4	TLR4	NNP
cord-347298-7kqrl3rv	444	18	)	)	-RRB-
cord-347298-7kqrl3rv	444	19	and	and	CC
cord-347298-7kqrl3rv	444	20	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	444	21	lipoproteins	lipoprotein	NNS
cord-347298-7kqrl3rv	444	22	(	(	-LRB-
cord-347298-7kqrl3rv	444	23	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	444	24	)	)	-RRB-
cord-347298-7kqrl3rv	444	25	,	,	,
cord-347298-7kqrl3rv	444	26	recent	recent	JJ
cord-347298-7kqrl3rv	444	27	data	datum	NNS
cord-347298-7kqrl3rv	444	28	show	show	VBP
cord-347298-7kqrl3rv	444	29	that	that	IN
cord-347298-7kqrl3rv	444	30	they	-PRON-	PRP
cord-347298-7kqrl3rv	444	31	can	can	MD
cord-347298-7kqrl3rv	444	32	also	also	RB
cord-347298-7kqrl3rv	444	33	be	be	VB
cord-347298-7kqrl3rv	444	34	activated	activate	VBN
cord-347298-7kqrl3rv	444	35	by	by	IN
cord-347298-7kqrl3rv	444	36	certain	certain	JJ
cord-347298-7kqrl3rv	444	37	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	444	38	molecules	molecule	NNS
cord-347298-7kqrl3rv	444	39	.	.	.
cord-347298-7kqrl3rv	445	1	The	the	DT
cord-347298-7kqrl3rv	445	2	ability	ability	NN
cord-347298-7kqrl3rv	445	3	of	of	IN
cord-347298-7kqrl3rv	445	4	preparations	preparation	NNS
cord-347298-7kqrl3rv	445	5	of	of	IN
cord-347298-7kqrl3rv	445	6	some	some	DT
cord-347298-7kqrl3rv	445	7	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	445	8	molecules	molecule	NNS
cord-347298-7kqrl3rv	445	9	,	,	,
cord-347298-7kqrl3rv	445	10	such	such	JJ
cord-347298-7kqrl3rv	445	11	as	as	IN
cord-347298-7kqrl3rv	445	12	heat	heat	NN
cord-347298-7kqrl3rv	445	13	-	-	HYPH
cord-347298-7kqrl3rv	445	14	shock	shock	NN
cord-347298-7kqrl3rv	445	15	proteins	protein	NNS
cord-347298-7kqrl3rv	445	16	,	,	,
cord-347298-7kqrl3rv	445	17	to	to	TO
cord-347298-7kqrl3rv	445	18	activate	activate	VB
cord-347298-7kqrl3rv	445	19	TLR	TLR	NNP
cord-347298-7kqrl3rv	445	20	signaling	signaling	NN
cord-347298-7kqrl3rv	445	21	is	be	VBZ
cord-347298-7kqrl3rv	445	22	now	now	RB
cord-347298-7kqrl3rv	445	23	attributed	attribute	VBN
cord-347298-7kqrl3rv	445	24	to	to	IN
cord-347298-7kqrl3rv	445	25	contamination	contamination	NN
cord-347298-7kqrl3rv	445	26	of	of	IN
cord-347298-7kqrl3rv	445	27	these	these	DT
cord-347298-7kqrl3rv	445	28	preparations	preparation	NNS
cord-347298-7kqrl3rv	445	29	by	by	IN
cord-347298-7kqrl3rv	445	30	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	445	31	products	product	NNS
cord-347298-7kqrl3rv	445	32	(	(	-LRB-
cord-347298-7kqrl3rv	445	33	Tsan	Tsan	NNP
cord-347298-7kqrl3rv	445	34	and	and	CC
cord-347298-7kqrl3rv	445	35	Gao	Gao	NNP
cord-347298-7kqrl3rv	445	36	2004	2004	CD
cord-347298-7kqrl3rv	445	37	)	)	-RRB-
cord-347298-7kqrl3rv	445	38	,	,	,
cord-347298-7kqrl3rv	445	39	but	but	CC
cord-347298-7kqrl3rv	445	40	there	there	EX
cord-347298-7kqrl3rv	445	41	is	be	VBZ
cord-347298-7kqrl3rv	445	42	convincing	convincing	JJ
cord-347298-7kqrl3rv	445	43	evidence	evidence	NN
cord-347298-7kqrl3rv	445	44	that	that	IN
cord-347298-7kqrl3rv	445	45	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	445	46	mRNA	mrna	NN
cord-347298-7kqrl3rv	445	47	is	be	VBZ
cord-347298-7kqrl3rv	445	48	a	a	DT
cord-347298-7kqrl3rv	445	49	ligand	ligand	NN
cord-347298-7kqrl3rv	445	50	for	for	IN
cord-347298-7kqrl3rv	445	51	TLR3	TLR3	NNP
cord-347298-7kqrl3rv	446	1	(	(	-LRB-
cord-347298-7kqrl3rv	446	2	Karikó	Karikó	NNP
cord-347298-7kqrl3rv	446	3	et	et	FW
cord-347298-7kqrl3rv	446	4	al	al	NNP
cord-347298-7kqrl3rv	446	5	.	.	.
cord-347298-7kqrl3rv	446	6	2004	2004	CD
cord-347298-7kqrl3rv	446	7	)	)	-RRB-
cord-347298-7kqrl3rv	446	8	and	and	CC
cord-347298-7kqrl3rv	446	9	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	446	10	CpG	CpG	NNP
cord-347298-7kqrl3rv	446	11	DNA	DNA	NNP
cord-347298-7kqrl3rv	446	12	can	can	MD
cord-347298-7kqrl3rv	446	13	activate	activate	VB
cord-347298-7kqrl3rv	446	14	TLR9	TLR9	NNP
cord-347298-7kqrl3rv	446	15	(	(	-LRB-
cord-347298-7kqrl3rv	446	16	Yasuda	Yasuda	NNP
cord-347298-7kqrl3rv	446	17	et	et	FW
cord-347298-7kqrl3rv	446	18	al	al	NNP
cord-347298-7kqrl3rv	446	19	.	.	NNP
cord-347298-7kqrl3rv	446	20	2005	2005	CD
cord-347298-7kqrl3rv	446	21	)	)	-RRB-
cord-347298-7kqrl3rv	446	22	.	.	.
cord-347298-7kqrl3rv	447	1	The	the	DT
cord-347298-7kqrl3rv	447	2	high	high	JJ
cord-347298-7kqrl3rv	447	3	mobility	mobility	NN
cord-347298-7kqrl3rv	447	4	group	group	NN
cord-347298-7kqrl3rv	447	5	box	box	NN
cord-347298-7kqrl3rv	447	6	chromosomal	chromosomal	NNP
cord-347298-7kqrl3rv	447	7	protein	protein	NNP
cord-347298-7kqrl3rv	447	8	1	1	CD
cord-347298-7kqrl3rv	447	9	(	(	-LRB-
cord-347298-7kqrl3rv	447	10	HMGB1	HMGB1	NNP
cord-347298-7kqrl3rv	447	11	)	)	-RRB-
cord-347298-7kqrl3rv	447	12	,	,	,
cord-347298-7kqrl3rv	447	13	produced	produce	VBN
cord-347298-7kqrl3rv	447	14	by	by	IN
cord-347298-7kqrl3rv	447	15	both	both	DT
cord-347298-7kqrl3rv	447	16	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	447	17	and	and	CC
cord-347298-7kqrl3rv	447	18	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	447	19	cells	cell	NNS
cord-347298-7kqrl3rv	447	20	,	,	,
cord-347298-7kqrl3rv	447	21	is	be	VBZ
cord-347298-7kqrl3rv	447	22	a	a	DT
cord-347298-7kqrl3rv	447	23	TLR2	TLR2	NNP
cord-347298-7kqrl3rv	447	24	and	and	CC
cord-347298-7kqrl3rv	447	25	4	4	CD
cord-347298-7kqrl3rv	447	26	ligand	ligand	NN
cord-347298-7kqrl3rv	448	1	(	(	-LRB-
cord-347298-7kqrl3rv	448	2	Yu	Yu	NNP
cord-347298-7kqrl3rv	448	3	et	et	FW
cord-347298-7kqrl3rv	448	4	al	al	NNP
cord-347298-7kqrl3rv	448	5	.	.	.
cord-347298-7kqrl3rv	449	1	2006	2006	CD
cord-347298-7kqrl3rv	449	2	;	;	:
cord-347298-7kqrl3rv	449	3	Zetterström	Zetterström	NNP
cord-347298-7kqrl3rv	449	4	et	et	FW
cord-347298-7kqrl3rv	449	5	al	al	NNP
cord-347298-7kqrl3rv	449	6	.	.	.
cord-347298-7kqrl3rv	449	7	2006	2006	CD
cord-347298-7kqrl3rv	449	8	)	)	-RRB-
cord-347298-7kqrl3rv	449	9	.	.	.
cord-347298-7kqrl3rv	450	1	Expression	expression	NN
cord-347298-7kqrl3rv	450	2	of	of	IN
cord-347298-7kqrl3rv	450	3	TLRs	TLRs	NNP
cord-347298-7kqrl3rv	450	4	by	by	IN
cord-347298-7kqrl3rv	450	5	the	the	DT
cord-347298-7kqrl3rv	450	6	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	450	7	cells	cell	NNS
cord-347298-7kqrl3rv	450	8	under	under	IN
cord-347298-7kqrl3rv	450	9	normal	normal	JJ
cord-347298-7kqrl3rv	450	10	conditions	condition	NNS
cord-347298-7kqrl3rv	450	11	,	,	,
cord-347298-7kqrl3rv	450	12	therefore	therefore	RB
cord-347298-7kqrl3rv	450	13	,	,	,
cord-347298-7kqrl3rv	450	14	suggests	suggest	VBZ
cord-347298-7kqrl3rv	450	15	a	a	DT
cord-347298-7kqrl3rv	450	16	potential	potential	JJ
cord-347298-7kqrl3rv	450	17	role	role	NN
cord-347298-7kqrl3rv	450	18	for	for	IN
cord-347298-7kqrl3rv	450	19	these	these	DT
cord-347298-7kqrl3rv	450	20	receptors	receptor	NNS
cord-347298-7kqrl3rv	450	21	in	in	IN
cord-347298-7kqrl3rv	450	22	responding	respond	VBG
cord-347298-7kqrl3rv	450	23	to	to	IN
cord-347298-7kqrl3rv	450	24	these	these	DT
cord-347298-7kqrl3rv	450	25	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	450	26	ligands	ligand	NNS
cord-347298-7kqrl3rv	450	27	.	.	.
cord-347298-7kqrl3rv	451	1	11.10.4.2.2	11.10.4.2.2	CD
cord-347298-7kqrl3rv	452	1	The	the	DT
cord-347298-7kqrl3rv	452	2	interleukin	interleukin	NN
cord-347298-7kqrl3rv	452	3	1	1	CD
cord-347298-7kqrl3rv	452	4	family	family	NN
cord-347298-7kqrl3rv	452	5	IL1	IL1	NNP
cord-347298-7kqrl3rv	452	6	is	be	VBZ
cord-347298-7kqrl3rv	452	7	the	the	DT
cord-347298-7kqrl3rv	452	8	best	well	RBS
cord-347298-7kqrl3rv	452	9	studied	study	VBN
cord-347298-7kqrl3rv	452	10	of	of	IN
cord-347298-7kqrl3rv	452	11	all	all	PDT
cord-347298-7kqrl3rv	452	12	the	the	DT
cord-347298-7kqrl3rv	452	13	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	452	14	normally	normally	RB
cord-347298-7kqrl3rv	452	15	expressed	express	VBN
cord-347298-7kqrl3rv	452	16	in	in	IN
cord-347298-7kqrl3rv	452	17	the	the	DT
cord-347298-7kqrl3rv	452	18	testis	testis	NN
cord-347298-7kqrl3rv	452	19	.	.	.
cord-347298-7kqrl3rv	453	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	453	2	is	be	VBZ
cord-347298-7kqrl3rv	453	3	produced	produce	VBN
cord-347298-7kqrl3rv	453	4	in	in	IN
cord-347298-7kqrl3rv	453	5	two	two	CD
cord-347298-7kqrl3rv	453	6	forms	form	NNS
cord-347298-7kqrl3rv	453	7	,	,	,
cord-347298-7kqrl3rv	453	8	and	and	CC
cord-347298-7kqrl3rv	453	9	,	,	,
cord-347298-7kqrl3rv	453	10	which	which	WDT
cord-347298-7kqrl3rv	453	11	are	be	VBP
cord-347298-7kqrl3rv	453	12	encoded	encode	VBN
cord-347298-7kqrl3rv	453	13	by	by	IN
cord-347298-7kqrl3rv	453	14	separate	separate	JJ
cord-347298-7kqrl3rv	453	15	genes	gene	NNS
cord-347298-7kqrl3rv	453	16	and	and	CC
cord-347298-7kqrl3rv	453	17	share	share	VBP
cord-347298-7kqrl3rv	453	18	approximately	approximately	RB
cord-347298-7kqrl3rv	453	19	25	25	CD
cord-347298-7kqrl3rv	453	20	%	%	NN
cord-347298-7kqrl3rv	453	21	sequence	sequence	NN
cord-347298-7kqrl3rv	453	22	homology	homology	NN
cord-347298-7kqrl3rv	453	23	.	.	.
cord-347298-7kqrl3rv	454	1	Both	both	DT
cord-347298-7kqrl3rv	454	2	forms	form	NNS
cord-347298-7kqrl3rv	454	3	act	act	VBP
cord-347298-7kqrl3rv	454	4	through	through	IN
cord-347298-7kqrl3rv	454	5	the	the	DT
cord-347298-7kqrl3rv	454	6	same	same	JJ
cord-347298-7kqrl3rv	454	7	receptor	receptor	NN
cord-347298-7kqrl3rv	454	8	complex	complex	NN
cord-347298-7kqrl3rv	454	9	(	(	-LRB-
cord-347298-7kqrl3rv	454	10	IL1R1	il1r1	NN
cord-347298-7kqrl3rv	454	11	)	)	-RRB-
cord-347298-7kqrl3rv	454	12	,	,	,
cord-347298-7kqrl3rv	454	13	and	and	CC
cord-347298-7kqrl3rv	454	14	exert	exert	VB
cord-347298-7kqrl3rv	454	15	a	a	DT
cord-347298-7kqrl3rv	454	16	similar	similar	JJ
cord-347298-7kqrl3rv	454	17	range	range	NN
cord-347298-7kqrl3rv	454	18	of	of	IN
cord-347298-7kqrl3rv	454	19	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	454	20	and	and	CC
cord-347298-7kqrl3rv	454	21	physiological	physiological	JJ
cord-347298-7kqrl3rv	454	22	effects	effect	NNS
cord-347298-7kqrl3rv	454	23	(	(	-LRB-
cord-347298-7kqrl3rv	454	24	Dinarello	Dinarello	NNP
cord-347298-7kqrl3rv	454	25	1996	1996	CD
cord-347298-7kqrl3rv	454	26	;	;	:
cord-347298-7kqrl3rv	454	27	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	454	28	and	and	CC
cord-347298-7kqrl3rv	454	29	Dinarello	Dinarello	NNP
cord-347298-7kqrl3rv	454	30	2000	2000	CD
cord-347298-7kqrl3rv	454	31	)	)	-RRB-
cord-347298-7kqrl3rv	454	32	.	.	.
cord-347298-7kqrl3rv	455	1	Most	Most	JJS
cord-347298-7kqrl3rv	455	2	IL1	IL1	NNP
cord-347298-7kqrl3rv	455	3	signaling	signaling	NN
cord-347298-7kqrl3rv	455	4	occurs	occur	VBZ
cord-347298-7kqrl3rv	455	5	through	through	IN
cord-347298-7kqrl3rv	455	6	activation	activation	NN
cord-347298-7kqrl3rv	455	7	of	of	IN
cord-347298-7kqrl3rv	455	8	the	the	DT
cord-347298-7kqrl3rv	455	9	MyD88	MyD88	NNP
cord-347298-7kqrl3rv	455	10	/	/	SYM
cord-347298-7kqrl3rv	455	11	TRAF	TRAF	NNP
cord-347298-7kqrl3rv	455	12	and	and	CC
cord-347298-7kqrl3rv	455	13	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	455	14	/	/	SYM
cord-347298-7kqrl3rv	455	15	p38	p38	CD
cord-347298-7kqrl3rv	455	16	MAP	MAP	NNP
cord-347298-7kqrl3rv	455	17	kinase	kinase	NN
cord-347298-7kqrl3rv	455	18	pathways	pathway	NNS
cord-347298-7kqrl3rv	455	19	,	,	,
cord-347298-7kqrl3rv	455	20	thereby	thereby	RB
cord-347298-7kqrl3rv	455	21	regulating	regulate	VBG
cord-347298-7kqrl3rv	455	22	many	many	JJ
cord-347298-7kqrl3rv	455	23	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	455	24	genes	gene	NNS
cord-347298-7kqrl3rv	455	25	through	through	IN
cord-347298-7kqrl3rv	455	26	stimulation	stimulation	NN
cord-347298-7kqrl3rv	455	27	of	of	IN
cord-347298-7kqrl3rv	455	28	the	the	DT
cord-347298-7kqrl3rv	455	29	transcription	transcription	NN
cord-347298-7kqrl3rv	455	30	factors	factor	NNS
cord-347298-7kqrl3rv	455	31	NFB	NFB	NNP
cord-347298-7kqrl3rv	455	32	and	and	CC
cord-347298-7kqrl3rv	455	33	activated	activate	VBD
cord-347298-7kqrl3rv	455	34	protein	protein	NN
cord-347298-7kqrl3rv	455	35	1	1	CD
cord-347298-7kqrl3rv	455	36	(	(	-LRB-
cord-347298-7kqrl3rv	455	37	AP1	AP1	NNP
cord-347298-7kqrl3rv	455	38	)	)	-RRB-
cord-347298-7kqrl3rv	456	1	(	(	-LRB-
cord-347298-7kqrl3rv	456	2	Medzhitov	Medzhitov	NNP
cord-347298-7kqrl3rv	456	3	et	et	NNP
cord-347298-7kqrl3rv	456	4	al	al	NNP
cord-347298-7kqrl3rv	456	5	.	.	NNP
cord-347298-7kqrl3rv	456	6	1998	1998	CD
cord-347298-7kqrl3rv	456	7	)	)	-RRB-
cord-347298-7kqrl3rv	456	8	.	.	.
cord-347298-7kqrl3rv	457	1	The	the	DT
cord-347298-7kqrl3rv	457	2	IL1s	IL1s	NNP
cord-347298-7kqrl3rv	457	3	are	be	VBP
cord-347298-7kqrl3rv	457	4	synthesized	synthesize	VBN
cord-347298-7kqrl3rv	457	5	as	as	IN
cord-347298-7kqrl3rv	457	6	precursor	precursor	NN
cord-347298-7kqrl3rv	457	7	proteins	protein	NNS
cord-347298-7kqrl3rv	457	8	,	,	,
cord-347298-7kqrl3rv	457	9	which	which	WDT
cord-347298-7kqrl3rv	457	10	are	be	VBP
cord-347298-7kqrl3rv	457	11	cleaved	cleave	VBN
cord-347298-7kqrl3rv	457	12	to	to	TO
cord-347298-7kqrl3rv	457	13	produce	produce	VB
cord-347298-7kqrl3rv	457	14	17	17	CD
cord-347298-7kqrl3rv	457	15	kDa	kDa	NNS
cord-347298-7kqrl3rv	457	16	active	active	JJ
cord-347298-7kqrl3rv	457	17	proteins	protein	NNS
cord-347298-7kqrl3rv	457	18	.	.	.
cord-347298-7kqrl3rv	458	1	In	in	IN
cord-347298-7kqrl3rv	458	2	the	the	DT
cord-347298-7kqrl3rv	458	3	case	case	NN
cord-347298-7kqrl3rv	458	4	of	of	IN
cord-347298-7kqrl3rv	458	5	IL1	IL1	NNP
cord-347298-7kqrl3rv	458	6	,	,	,
cord-347298-7kqrl3rv	458	7	the	the	DT
cord-347298-7kqrl3rv	458	8	precursor	precursor	NN
cord-347298-7kqrl3rv	458	9	possesses	possess	VBZ
cord-347298-7kqrl3rv	458	10	low	low	JJ
cord-347298-7kqrl3rv	458	11	-	-	HYPH
cord-347298-7kqrl3rv	458	12	level	level	NN
cord-347298-7kqrl3rv	458	13	biological	biological	JJ
cord-347298-7kqrl3rv	458	14	activity	activity	NN
cord-347298-7kqrl3rv	458	15	,	,	,
cord-347298-7kqrl3rv	458	16	but	but	CC
cord-347298-7kqrl3rv	458	17	the	the	DT
cord-347298-7kqrl3rv	458	18	IL1	IL1	NNP
cord-347298-7kqrl3rv	458	19	precursor	precursor	NN
cord-347298-7kqrl3rv	458	20	protein	protein	NN
cord-347298-7kqrl3rv	458	21	is	be	VBZ
cord-347298-7kqrl3rv	458	22	inactive	inactive	JJ
cord-347298-7kqrl3rv	459	1	(	(	-LRB-
cord-347298-7kqrl3rv	459	2	Black	Black	NNP
cord-347298-7kqrl3rv	459	3	et	et	NNP
cord-347298-7kqrl3rv	459	4	al	al	NNP
cord-347298-7kqrl3rv	459	5	.	.	.
cord-347298-7kqrl3rv	460	1	1988	1988	CD
cord-347298-7kqrl3rv	460	2	;	;	:
cord-347298-7kqrl3rv	460	3	Watanabe	Watanabe	NNP
cord-347298-7kqrl3rv	460	4	and	and	CC
cord-347298-7kqrl3rv	460	5	Kobayashi	Kobayashi	NNP
cord-347298-7kqrl3rv	460	6	1994	1994	CD
cord-347298-7kqrl3rv	460	7	)	)	-RRB-
cord-347298-7kqrl3rv	460	8	.	.	.
cord-347298-7kqrl3rv	461	1	The	the	DT
cord-347298-7kqrl3rv	461	2	precursor	precursor	NN
cord-347298-7kqrl3rv	461	3	of	of	IN
cord-347298-7kqrl3rv	461	4	IL1	IL1	NNP
cord-347298-7kqrl3rv	461	5	is	be	VBZ
cord-347298-7kqrl3rv	461	6	cleaved	cleave	VBN
cord-347298-7kqrl3rv	461	7	by	by	IN
cord-347298-7kqrl3rv	461	8	the	the	DT
cord-347298-7kqrl3rv	461	9	IL1	IL1	NNP
cord-347298-7kqrl3rv	461	10	converting	convert	VBG
cord-347298-7kqrl3rv	461	11	enzyme	enzyme	NN
cord-347298-7kqrl3rv	461	12	(	(	-LRB-
cord-347298-7kqrl3rv	461	13	ICE	ice	NN
cord-347298-7kqrl3rv	461	14	,	,	,
cord-347298-7kqrl3rv	461	15	caspase	caspase	NN
cord-347298-7kqrl3rv	461	16	1	1	CD
cord-347298-7kqrl3rv	461	17	)	)	-RRB-
cord-347298-7kqrl3rv	461	18	during	during	IN
cord-347298-7kqrl3rv	461	19	the	the	DT
cord-347298-7kqrl3rv	461	20	process	process	NN
cord-347298-7kqrl3rv	461	21	of	of	IN
cord-347298-7kqrl3rv	461	22	secretion	secretion	NN
cord-347298-7kqrl3rv	461	23	,	,	,
cord-347298-7kqrl3rv	461	24	whereas	whereas	IN
cord-347298-7kqrl3rv	461	25	IL1	IL1	NNP
cord-347298-7kqrl3rv	461	26	is	be	VBZ
cord-347298-7kqrl3rv	461	27	cleaved	cleave	VBN
cord-347298-7kqrl3rv	461	28	by	by	IN
cord-347298-7kqrl3rv	461	29	the	the	DT
cord-347298-7kqrl3rv	461	30	calcium	calcium	NN
cord-347298-7kqrl3rv	461	31	-	-	HYPH
cord-347298-7kqrl3rv	461	32	dependent	dependent	JJ
cord-347298-7kqrl3rv	461	33	membrane	membrane	NN
cord-347298-7kqrl3rv	461	34	-	-	HYPH
cord-347298-7kqrl3rv	461	35	associated	associate	VBN
cord-347298-7kqrl3rv	461	36	cysteine	cysteine	NN
cord-347298-7kqrl3rv	461	37	protease	protease	NN
cord-347298-7kqrl3rv	461	38	(	(	-LRB-
cord-347298-7kqrl3rv	461	39	calpain	calpain	NNP
cord-347298-7kqrl3rv	461	40	)	)	-RRB-
cord-347298-7kqrl3rv	461	41	or	or	CC
cord-347298-7kqrl3rv	461	42	by	by	IN
cord-347298-7kqrl3rv	461	43	extracellular	extracellular	JJ
cord-347298-7kqrl3rv	461	44	proteases	protease	NNS
cord-347298-7kqrl3rv	461	45	(	(	-LRB-
cord-347298-7kqrl3rv	461	46	Thornberry	Thornberry	NNP
cord-347298-7kqrl3rv	461	47	and	and	CC
cord-347298-7kqrl3rv	461	48	Molineaux	Molineaux	NNP
cord-347298-7kqrl3rv	461	49	1995	1995	CD
cord-347298-7kqrl3rv	461	50	;	;	:
cord-347298-7kqrl3rv	461	51	Watanabe	Watanabe	NNP
cord-347298-7kqrl3rv	461	52	and	and	CC
cord-347298-7kqrl3rv	461	53	Kobayashi	Kobayashi	NNP
cord-347298-7kqrl3rv	461	54	1994	1994	CD
cord-347298-7kqrl3rv	461	55	)	)	-RRB-
cord-347298-7kqrl3rv	461	56	.	.	.
cord-347298-7kqrl3rv	462	1	IL1	IL1	NNP
cord-347298-7kqrl3rv	462	2	is	be	VBZ
cord-347298-7kqrl3rv	462	3	produced	produce	VBN
cord-347298-7kqrl3rv	462	4	by	by	IN
cord-347298-7kqrl3rv	462	5	activated	activate	VBN
cord-347298-7kqrl3rv	462	6	monocyte	monocyte	NNP
cord-347298-7kqrl3rv	462	7	/	/	SYM
cord-347298-7kqrl3rv	462	8	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	462	9	and	and	CC
cord-347298-7kqrl3rv	462	10	is	be	VBZ
cord-347298-7kqrl3rv	462	11	the	the	DT
cord-347298-7kqrl3rv	462	12	main	main	JJ
cord-347298-7kqrl3rv	462	13	secreted	secrete	VBN
cord-347298-7kqrl3rv	462	14	form	form	NN
cord-347298-7kqrl3rv	462	15	during	during	IN
cord-347298-7kqrl3rv	462	16	inflammation	inflammation	NN
cord-347298-7kqrl3rv	462	17	,	,	,
cord-347298-7kqrl3rv	462	18	whereas	whereas	IN
cord-347298-7kqrl3rv	462	19	IL1	IL1	NNP
cord-347298-7kqrl3rv	462	20	is	be	VBZ
cord-347298-7kqrl3rv	462	21	more	more	RBR
cord-347298-7kqrl3rv	462	22	commonly	commonly	RB
cord-347298-7kqrl3rv	462	23	found	find	VBN
cord-347298-7kqrl3rv	462	24	within	within	IN
cord-347298-7kqrl3rv	462	25	the	the	DT
cord-347298-7kqrl3rv	462	26	cell	cell	NN
cord-347298-7kqrl3rv	462	27	,	,	,
cord-347298-7kqrl3rv	462	28	where	where	WRB
cord-347298-7kqrl3rv	462	29	it	-PRON-	PRP
cord-347298-7kqrl3rv	462	30	may	may	MD
cord-347298-7kqrl3rv	462	31	act	act	VB
cord-347298-7kqrl3rv	462	32	as	as	IN
cord-347298-7kqrl3rv	462	33	an	an	DT
cord-347298-7kqrl3rv	462	34	autocrine	autocrine	JJ
cord-347298-7kqrl3rv	462	35	or	or	CC
cord-347298-7kqrl3rv	462	36	paracrine	paracrine	JJ
cord-347298-7kqrl3rv	462	37	growth	growth	NN
cord-347298-7kqrl3rv	462	38	factor	factor	NN
cord-347298-7kqrl3rv	462	39	involved	involve	VBN
cord-347298-7kqrl3rv	462	40	in	in	IN
cord-347298-7kqrl3rv	462	41	direct	direct	JJ
cord-347298-7kqrl3rv	462	42	cell	cell	NN
cord-347298-7kqrl3rv	462	43	-	-	HYPH
cord-347298-7kqrl3rv	462	44	to	to	IN
cord-347298-7kqrl3rv	462	45	-	-	HYPH
cord-347298-7kqrl3rv	462	46	cell	cell	NN
cord-347298-7kqrl3rv	462	47	communication	communication	NN
cord-347298-7kqrl3rv	462	48	.	.	.
cord-347298-7kqrl3rv	463	1	In	in	IN
cord-347298-7kqrl3rv	463	2	addition	addition	NN
cord-347298-7kqrl3rv	463	3	to	to	IN
cord-347298-7kqrl3rv	463	4	the	the	DT
cord-347298-7kqrl3rv	463	5	prototypical	prototypical	JJ
cord-347298-7kqrl3rv	463	6	IL1	IL1	NNP
cord-347298-7kqrl3rv	463	7	and	and	CC
cord-347298-7kqrl3rv	463	8	IL1	IL1	NNP
cord-347298-7kqrl3rv	463	9	,	,	,
cord-347298-7kqrl3rv	463	10	the	the	DT
cord-347298-7kqrl3rv	463	11	IL1	IL1	NNP
cord-347298-7kqrl3rv	463	12	family	family	NN
cord-347298-7kqrl3rv	463	13	comprises	comprise	VBZ
cord-347298-7kqrl3rv	463	14	a	a	DT
cord-347298-7kqrl3rv	463	15	number	number	NN
cord-347298-7kqrl3rv	463	16	of	of	IN
cord-347298-7kqrl3rv	463	17	structurally	structurally	RB
cord-347298-7kqrl3rv	463	18	related	relate	VBN
cord-347298-7kqrl3rv	463	19	proteins	protein	NNS
cord-347298-7kqrl3rv	463	20	,	,	,
cord-347298-7kqrl3rv	463	21	which	which	WDT
cord-347298-7kqrl3rv	463	22	appear	appear	VBP
cord-347298-7kqrl3rv	463	23	to	to	TO
cord-347298-7kqrl3rv	463	24	have	have	VB
cord-347298-7kqrl3rv	463	25	arisen	arise	VBN
cord-347298-7kqrl3rv	463	26	by	by	IN
cord-347298-7kqrl3rv	463	27	gene	gene	NN
cord-347298-7kqrl3rv	463	28	duplication	duplication	NN
cord-347298-7kqrl3rv	463	29	(	(	-LRB-
cord-347298-7kqrl3rv	463	30	Dunn	Dunn	NNP
cord-347298-7kqrl3rv	463	31	et	et	NNP
cord-347298-7kqrl3rv	463	32	al	al	NNP
cord-347298-7kqrl3rv	463	33	.	.	NNP
cord-347298-7kqrl3rv	463	34	2001	2001	CD
cord-347298-7kqrl3rv	463	35	)	)	-RRB-
cord-347298-7kqrl3rv	463	36	.	.	.
cord-347298-7kqrl3rv	464	1	The	the	DT
cord-347298-7kqrl3rv	464	2	closest	close	JJS
cord-347298-7kqrl3rv	464	3	structurally	structurally	RB
cord-347298-7kqrl3rv	464	4	to	to	IN
cord-347298-7kqrl3rv	464	5	IL1/	IL1/	NNP
cord-347298-7kqrl3rv	464	6	is	be	VBZ
cord-347298-7kqrl3rv	464	7	IL18	IL18	NNP
cord-347298-7kqrl3rv	464	8	,	,	,
cord-347298-7kqrl3rv	464	9	which	which	WDT
cord-347298-7kqrl3rv	464	10	is	be	VBZ
cord-347298-7kqrl3rv	464	11	processed	process	VBN
cord-347298-7kqrl3rv	464	12	by	by	IN
cord-347298-7kqrl3rv	464	13	caspase	caspase	NN
cord-347298-7kqrl3rv	464	14	1	1	CD
cord-347298-7kqrl3rv	464	15	activity	activity	NN
cord-347298-7kqrl3rv	464	16	,	,	,
cord-347298-7kqrl3rv	464	17	but	but	CC
cord-347298-7kqrl3rv	464	18	acts	act	VBZ
cord-347298-7kqrl3rv	464	19	via	via	IN
cord-347298-7kqrl3rv	464	20	a	a	DT
cord-347298-7kqrl3rv	464	21	separate	separate	JJ
cord-347298-7kqrl3rv	464	22	receptor	receptor	NN
cord-347298-7kqrl3rv	464	23	rather	rather	RB
cord-347298-7kqrl3rv	464	24	than	than	IN
cord-347298-7kqrl3rv	464	25	IL1R1	il1r1	NN
cord-347298-7kqrl3rv	465	1	(	(	-LRB-
cord-347298-7kqrl3rv	465	2	Gracie	Gracie	NNP
cord-347298-7kqrl3rv	465	3	et	et	NNP
cord-347298-7kqrl3rv	465	4	al	al	NNP
cord-347298-7kqrl3rv	465	5	.	.	NNP
cord-347298-7kqrl3rv	465	6	2003	2003	CD
cord-347298-7kqrl3rv	465	7	)	)	-RRB-
cord-347298-7kqrl3rv	465	8	.	.	.
cord-347298-7kqrl3rv	466	1	Another	another	DT
cord-347298-7kqrl3rv	466	2	member	member	NN
cord-347298-7kqrl3rv	466	3	of	of	IN
cord-347298-7kqrl3rv	466	4	the	the	DT
cord-347298-7kqrl3rv	466	5	family	family	NN
cord-347298-7kqrl3rv	466	6	,	,	,
cord-347298-7kqrl3rv	466	7	which	which	WDT
cord-347298-7kqrl3rv	466	8	does	do	VBZ
cord-347298-7kqrl3rv	466	9	bind	bind	VB
cord-347298-7kqrl3rv	466	10	to	to	IN
cord-347298-7kqrl3rv	466	11	IL1R1	il1r1	NN
cord-347298-7kqrl3rv	466	12	but	but	CC
cord-347298-7kqrl3rv	466	13	lacks	lack	VBZ
cord-347298-7kqrl3rv	466	14	the	the	DT
cord-347298-7kqrl3rv	466	15	ability	ability	NN
cord-347298-7kqrl3rv	466	16	to	to	TO
cord-347298-7kqrl3rv	466	17	transduce	transduce	VB
cord-347298-7kqrl3rv	466	18	a	a	DT
cord-347298-7kqrl3rv	466	19	signal	signal	NN
cord-347298-7kqrl3rv	466	20	,	,	,
cord-347298-7kqrl3rv	466	21	blocks	block	VBZ
cord-347298-7kqrl3rv	466	22	IL1/	IL1/	NNP
cord-347298-7kqrl3rv	466	23	action	action	NN
cord-347298-7kqrl3rv	466	24	and	and	CC
cord-347298-7kqrl3rv	466	25	is	be	VBZ
cord-347298-7kqrl3rv	466	26	called	call	VBN
cord-347298-7kqrl3rv	466	27	IL1	IL1	NNP
cord-347298-7kqrl3rv	466	28	receptor	receptor	NN
cord-347298-7kqrl3rv	466	29	antagonist	antagonist	NN
cord-347298-7kqrl3rv	466	30	(	(	-LRB-
cord-347298-7kqrl3rv	466	31	IL1ra	IL1ra	NNP
cord-347298-7kqrl3rv	466	32	)	)	-RRB-
cord-347298-7kqrl3rv	466	33	(	(	-LRB-
cord-347298-7kqrl3rv	466	34	Arend	Arend	NNP
cord-347298-7kqrl3rv	466	35	1991	1991	CD
cord-347298-7kqrl3rv	466	36	)	)	-RRB-
cord-347298-7kqrl3rv	466	37	.	.	.
cord-347298-7kqrl3rv	467	1	Production	production	NN
cord-347298-7kqrl3rv	467	2	of	of	IN
cord-347298-7kqrl3rv	467	3	IL1	IL1	NNP
cord-347298-7kqrl3rv	467	4	is	be	VBZ
cord-347298-7kqrl3rv	467	5	constitutively	constitutively	RB
cord-347298-7kqrl3rv	467	6	high	high	JJ
cord-347298-7kqrl3rv	467	7	in	in	IN
cord-347298-7kqrl3rv	467	8	the	the	DT
cord-347298-7kqrl3rv	467	9	normal	normal	JJ
cord-347298-7kqrl3rv	467	10	testis	testis	NN
cord-347298-7kqrl3rv	467	11	,	,	,
cord-347298-7kqrl3rv	467	12	as	as	IN
cord-347298-7kqrl3rv	467	13	IL1	IL1	NNP
cord-347298-7kqrl3rv	467	14	is	be	VBZ
cord-347298-7kqrl3rv	467	15	produced	produce	VBN
cord-347298-7kqrl3rv	467	16	by	by	IN
cord-347298-7kqrl3rv	467	17	the	the	DT
cord-347298-7kqrl3rv	467	18	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	467	19	cells	cell	NNS
cord-347298-7kqrl3rv	467	20	in	in	IN
cord-347298-7kqrl3rv	467	21	a	a	DT
cord-347298-7kqrl3rv	467	22	cyclical	cyclical	JJ
cord-347298-7kqrl3rv	467	23	manner	manner	NN
cord-347298-7kqrl3rv	467	24	within	within	IN
cord-347298-7kqrl3rv	467	25	the	the	DT
cord-347298-7kqrl3rv	467	26	mature	mature	JJ
cord-347298-7kqrl3rv	467	27	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	467	28	epithelium	epithelium	NN
cord-347298-7kqrl3rv	468	1	(	(	-LRB-
cord-347298-7kqrl3rv	468	2	Jonsson	Jonsson	NNP
cord-347298-7kqrl3rv	468	3	et	et	NNP
cord-347298-7kqrl3rv	468	4	al	al	NNP
cord-347298-7kqrl3rv	468	5	.	.	.
cord-347298-7kqrl3rv	468	6	1999	1999	CD
cord-347298-7kqrl3rv	469	1	;	;	:
cord-347298-7kqrl3rv	469	2	Söder	Söder	NNP
cord-347298-7kqrl3rv	469	3	et	et	NNP
cord-347298-7kqrl3rv	469	4	al	al	NNP
cord-347298-7kqrl3rv	469	5	.	.	NNP
cord-347298-7kqrl3rv	469	6	1991	1991	CD
cord-347298-7kqrl3rv	469	7	)	)	-RRB-
cord-347298-7kqrl3rv	469	8	.	.	.
cord-347298-7kqrl3rv	470	1	Its	-PRON-	PRP$
cord-347298-7kqrl3rv	470	2	production	production	NN
cord-347298-7kqrl3rv	470	3	is	be	VBZ
cord-347298-7kqrl3rv	470	4	driven	drive	VBN
cord-347298-7kqrl3rv	470	5	by	by	IN
cord-347298-7kqrl3rv	470	6	the	the	DT
cord-347298-7kqrl3rv	470	7	developing	develop	VBG
cord-347298-7kqrl3rv	470	8	germ	germ	NN
cord-347298-7kqrl3rv	470	9	cells	cell	NNS
cord-347298-7kqrl3rv	470	10	and	and	CC
cord-347298-7kqrl3rv	470	11	by	by	IN
cord-347298-7kqrl3rv	470	12	phagocytosis	phagocytosis	NN
cord-347298-7kqrl3rv	470	13	of	of	IN
cord-347298-7kqrl3rv	470	14	the	the	DT
cord-347298-7kqrl3rv	470	15	residual	residual	JJ
cord-347298-7kqrl3rv	470	16	cytoplasm	cytoplasm	NN
cord-347298-7kqrl3rv	470	17	cast	cast	VBN
cord-347298-7kqrl3rv	470	18	off	off	RP
cord-347298-7kqrl3rv	470	19	by	by	IN
cord-347298-7kqrl3rv	470	20	the	the	DT
cord-347298-7kqrl3rv	470	21	spermatids	spermatid	NNS
cord-347298-7kqrl3rv	470	22	at	at	IN
cord-347298-7kqrl3rv	470	23	the	the	DT
cord-347298-7kqrl3rv	470	24	time	time	NN
cord-347298-7kqrl3rv	470	25	of	of	IN
cord-347298-7kqrl3rv	470	26	their	-PRON-	PRP$
cord-347298-7kqrl3rv	470	27	release	release	NN
cord-347298-7kqrl3rv	470	28	into	into	IN
cord-347298-7kqrl3rv	470	29	the	the	DT
cord-347298-7kqrl3rv	470	30	tubule	tubule	NN
cord-347298-7kqrl3rv	470	31	lumen	lumen	NN
cord-347298-7kqrl3rv	470	32	(	(	-LRB-
cord-347298-7kqrl3rv	470	33	Gérard	Gérard	NNP
cord-347298-7kqrl3rv	470	34	et	et	FW
cord-347298-7kqrl3rv	470	35	al	al	NNP
cord-347298-7kqrl3rv	470	36	.	.	NNP
cord-347298-7kqrl3rv	470	37	1992	1992	CD
cord-347298-7kqrl3rv	470	38	;	;	:
cord-347298-7kqrl3rv	470	39	Syed	Syed	NNP
cord-347298-7kqrl3rv	470	40	et	et	NNP
cord-347298-7kqrl3rv	470	41	al	al	NNP
cord-347298-7kqrl3rv	470	42	.	.	NNP
cord-347298-7kqrl3rv	470	43	1995	1995	CD
cord-347298-7kqrl3rv	470	44	)	)	-RRB-
cord-347298-7kqrl3rv	470	45	.	.	.
cord-347298-7kqrl3rv	471	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	471	2	cell	cell	NN
cord-347298-7kqrl3rv	471	3	IL1	IL1	NNP
cord-347298-7kqrl3rv	471	4	production	production	NN
cord-347298-7kqrl3rv	471	5	is	be	VBZ
cord-347298-7kqrl3rv	471	6	also	also	RB
cord-347298-7kqrl3rv	471	7	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	471	8	by	by	IN
cord-347298-7kqrl3rv	471	9	LPS	LPS	NNP
cord-347298-7kqrl3rv	471	10	,	,	,
cord-347298-7kqrl3rv	471	11	but	but	CC
cord-347298-7kqrl3rv	471	12	not	not	RB
cord-347298-7kqrl3rv	471	13	by	by	IN
cord-347298-7kqrl3rv	471	14	FSH	fsh	NN
cord-347298-7kqrl3rv	472	1	(	(	-LRB-
cord-347298-7kqrl3rv	472	2	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	472	3	et	et	FW
cord-347298-7kqrl3rv	472	4	al	al	NNP
cord-347298-7kqrl3rv	472	5	.	.	.
cord-347298-7kqrl3rv	472	6	1997	1997	CD
cord-347298-7kqrl3rv	472	7	)	)	-RRB-
cord-347298-7kqrl3rv	472	8	.	.	.
cord-347298-7kqrl3rv	473	1	Production	production	NN
cord-347298-7kqrl3rv	473	2	of	of	IN
cord-347298-7kqrl3rv	473	3	IL1	IL1	NNP
cord-347298-7kqrl3rv	473	4	by	by	IN
cord-347298-7kqrl3rv	473	5	the	the	DT
cord-347298-7kqrl3rv	473	6	normal	normal	JJ
cord-347298-7kqrl3rv	473	7	testis	testis	NN
cord-347298-7kqrl3rv	473	8	is	be	VBZ
cord-347298-7kqrl3rv	473	9	low	low	JJ
cord-347298-7kqrl3rv	473	10	,	,	,
cord-347298-7kqrl3rv	473	11	but	but	CC
cord-347298-7kqrl3rv	473	12	is	be	VBZ
cord-347298-7kqrl3rv	473	13	upregulated	upregulate	VBN
cord-347298-7kqrl3rv	473	14	in	in	IN
cord-347298-7kqrl3rv	473	15	a	a	DT
cord-347298-7kqrl3rv	473	16	subset	subset	NN
cord-347298-7kqrl3rv	473	17	of	of	IN
cord-347298-7kqrl3rv	473	18	testicular	testicular	JJ
cord-347298-7kqrl3rv	473	19	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	473	20	and	and	CC
cord-347298-7kqrl3rv	473	21	the	the	DT
cord-347298-7kqrl3rv	473	22	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	473	23	cells	cell	NNS
cord-347298-7kqrl3rv	473	24	during	during	IN
cord-347298-7kqrl3rv	473	25	inflammation	inflammation	NN
cord-347298-7kqrl3rv	473	26	(	(	-LRB-
cord-347298-7kqrl3rv	473	27	Gérard	Gérard	NNP
cord-347298-7kqrl3rv	473	28	et	et	FW
cord-347298-7kqrl3rv	473	29	al	al	NNP
cord-347298-7kqrl3rv	473	30	.	.	NNP
cord-347298-7kqrl3rv	473	31	1991	1991	CD
cord-347298-7kqrl3rv	473	32	;	;	:
cord-347298-7kqrl3rv	474	1	Jonsson	Jonsson	NNP
cord-347298-7kqrl3rv	474	2	et	et	NNP
cord-347298-7kqrl3rv	474	3	al	al	NNP
cord-347298-7kqrl3rv	474	4	.	.	.
cord-347298-7kqrl3rv	475	1	1999	1999	CD
cord-347298-7kqrl3rv	475	2	;	;	:
cord-347298-7kqrl3rv	475	3	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	475	4	et	et	NNP
cord-347298-7kqrl3rv	475	5	al	al	NNP
cord-347298-7kqrl3rv	475	6	.	.	NNP
cord-347298-7kqrl3rv	475	7	2005	2005	CD
cord-347298-7kqrl3rv	475	8	)	)	-RRB-
cord-347298-7kqrl3rv	475	9	.	.	.
cord-347298-7kqrl3rv	476	1	Curiously	curiously	RB
cord-347298-7kqrl3rv	476	2	,	,	,
cord-347298-7kqrl3rv	476	3	the	the	DT
cord-347298-7kqrl3rv	476	4	majority	majority	NN
cord-347298-7kqrl3rv	476	5	of	of	IN
cord-347298-7kqrl3rv	476	6	this	this	DT
cord-347298-7kqrl3rv	476	7	secreted	secrete	VBN
cord-347298-7kqrl3rv	476	8	testicular	testicular	NN
cord-347298-7kqrl3rv	476	9	IL1	IL1	NNP
cord-347298-7kqrl3rv	476	10	exists	exist	VBZ
cord-347298-7kqrl3rv	476	11	as	as	IN
cord-347298-7kqrl3rv	476	12	the	the	DT
cord-347298-7kqrl3rv	476	13	precursor	precursor	NN
cord-347298-7kqrl3rv	476	14	(	(	-LRB-
cord-347298-7kqrl3rv	476	15	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	476	16	et	et	NNP
cord-347298-7kqrl3rv	476	17	al	al	NNP
cord-347298-7kqrl3rv	476	18	.	.	NNP
cord-347298-7kqrl3rv	476	19	2005	2005	CD
cord-347298-7kqrl3rv	476	20	)	)	-RRB-
cord-347298-7kqrl3rv	476	21	.	.	.
cord-347298-7kqrl3rv	477	1	The	the	DT
cord-347298-7kqrl3rv	477	2	receptor	receptor	NN
cord-347298-7kqrl3rv	477	3	IL1R1	il1r1	NN
cord-347298-7kqrl3rv	477	4	has	have	VBZ
cord-347298-7kqrl3rv	477	5	been	be	VBN
cord-347298-7kqrl3rv	477	6	localized	localize	VBN
cord-347298-7kqrl3rv	477	7	to	to	IN
cord-347298-7kqrl3rv	477	8	germ	germ	NN
cord-347298-7kqrl3rv	477	9	cells	cell	NNS
cord-347298-7kqrl3rv	477	10	and	and	CC
cord-347298-7kqrl3rv	477	11	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	477	12	cells	cell	NNS
cord-347298-7kqrl3rv	478	1	(	(	-LRB-
cord-347298-7kqrl3rv	478	2	Gomez	Gomez	NNP
cord-347298-7kqrl3rv	478	3	et	et	NNP
cord-347298-7kqrl3rv	478	4	al	al	NNP
cord-347298-7kqrl3rv	478	5	.	.	.
cord-347298-7kqrl3rv	478	6	1997	1997	CD
cord-347298-7kqrl3rv	478	7	)	)	-RRB-
cord-347298-7kqrl3rv	478	8	.	.	.
cord-347298-7kqrl3rv	479	1	IL1	IL1	NNP
cord-347298-7kqrl3rv	479	2	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	479	3	DNA	dna	NN
cord-347298-7kqrl3rv	479	4	synthesis	synthesis	NN
cord-347298-7kqrl3rv	479	5	in	in	IN
cord-347298-7kqrl3rv	479	6	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	479	7	(	(	-LRB-
cord-347298-7kqrl3rv	479	8	i.e.	i.e.	FW
cord-347298-7kqrl3rv	479	9	,	,	,
cord-347298-7kqrl3rv	479	10	mitosis	mitosis	NN
cord-347298-7kqrl3rv	479	11	)	)	-RRB-
cord-347298-7kqrl3rv	479	12	and	and	CC
cord-347298-7kqrl3rv	479	13	early	early	JJ
cord-347298-7kqrl3rv	479	14	spermatocytes	spermatocyte	NNS
cord-347298-7kqrl3rv	479	15	(	(	-LRB-
cord-347298-7kqrl3rv	479	16	i.e.	i.e.	FW
cord-347298-7kqrl3rv	479	17	,	,	,
cord-347298-7kqrl3rv	479	18	meiosis	meiosis	NN
cord-347298-7kqrl3rv	479	19	)	)	-RRB-
cord-347298-7kqrl3rv	479	20	,	,	,
cord-347298-7kqrl3rv	479	21	proliferation	proliferation	NN
cord-347298-7kqrl3rv	479	22	of	of	IN
cord-347298-7kqrl3rv	479	23	immature	immature	JJ
cord-347298-7kqrl3rv	479	24	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	479	25	cells	cell	NNS
cord-347298-7kqrl3rv	479	26	,	,	,
cord-347298-7kqrl3rv	479	27	and	and	CC
cord-347298-7kqrl3rv	479	28	a	a	DT
cord-347298-7kqrl3rv	479	29	number	number	NN
cord-347298-7kqrl3rv	479	30	of	of	IN
cord-347298-7kqrl3rv	479	31	activities	activity	NNS
cord-347298-7kqrl3rv	479	32	of	of	IN
cord-347298-7kqrl3rv	479	33	the	the	DT
cord-347298-7kqrl3rv	479	34	mature	mature	JJ
cord-347298-7kqrl3rv	479	35	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	479	36	cell	cell	NN
cord-347298-7kqrl3rv	479	37	that	that	WDT
cord-347298-7kqrl3rv	479	38	support	support	VBP
cord-347298-7kqrl3rv	479	39	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	479	40	,	,	,
cord-347298-7kqrl3rv	479	41	such	such	JJ
cord-347298-7kqrl3rv	479	42	as	as	IN
cord-347298-7kqrl3rv	479	43	the	the	DT
cord-347298-7kqrl3rv	479	44	production	production	NN
cord-347298-7kqrl3rv	479	45	of	of	IN
cord-347298-7kqrl3rv	479	46	lactate	lactate	NN
cord-347298-7kqrl3rv	479	47	and	and	CC
cord-347298-7kqrl3rv	479	48	transferrin	transferrin	NN
cord-347298-7kqrl3rv	479	49	(	(	-LRB-
cord-347298-7kqrl3rv	479	50	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	479	51	et	et	NNP
cord-347298-7kqrl3rv	479	52	al	al	NNP
cord-347298-7kqrl3rv	479	53	.	.	NNP
cord-347298-7kqrl3rv	479	54	1993b	1993b	CD
cord-347298-7kqrl3rv	479	55	;	;	:
cord-347298-7kqrl3rv	479	56	Hoeben	Hoeben	NNP
cord-347298-7kqrl3rv	479	57	et	et	NNP
cord-347298-7kqrl3rv	479	58	al	al	NNP
cord-347298-7kqrl3rv	479	59	.	.	.
cord-347298-7kqrl3rv	479	60	1996	1996	CD
cord-347298-7kqrl3rv	479	61	;	;	:
cord-347298-7kqrl3rv	479	62	Nehar	Nehar	NNP
cord-347298-7kqrl3rv	479	63	et	et	NNP
cord-347298-7kqrl3rv	479	64	al	al	NNP
cord-347298-7kqrl3rv	479	65	.	.	.
cord-347298-7kqrl3rv	480	1	1998	1998	CD
cord-347298-7kqrl3rv	480	2	;	;	:
cord-347298-7kqrl3rv	480	3	Parvinen	Parvinen	NNP
cord-347298-7kqrl3rv	480	4	et	et	NNP
cord-347298-7kqrl3rv	480	5	al	al	NNP
cord-347298-7kqrl3rv	480	6	.	.	.
cord-347298-7kqrl3rv	481	1	1991	1991	CD
cord-347298-7kqrl3rv	481	2	;	;	:
cord-347298-7kqrl3rv	481	3	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	481	4	et	et	NNP
cord-347298-7kqrl3rv	481	5	al	al	NNP
cord-347298-7kqrl3rv	481	6	.	.	NNP
cord-347298-7kqrl3rv	481	7	1989	1989	CD
cord-347298-7kqrl3rv	481	8	;	;	:
cord-347298-7kqrl3rv	481	9	Söder	Söder	NNP
cord-347298-7kqrl3rv	481	10	et	et	NNP
cord-347298-7kqrl3rv	481	11	al	al	NNP
cord-347298-7kqrl3rv	481	12	.	.	NNP
cord-347298-7kqrl3rv	481	13	1991	1991	CD
cord-347298-7kqrl3rv	481	14	)	)	-RRB-
cord-347298-7kqrl3rv	481	15	.	.	.
cord-347298-7kqrl3rv	482	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	482	2	also	also	RB
cord-347298-7kqrl3rv	482	3	regulates	regulate	VBZ
cord-347298-7kqrl3rv	482	4	the	the	DT
cord-347298-7kqrl3rv	482	5	ability	ability	NN
cord-347298-7kqrl3rv	482	6	of	of	IN
cord-347298-7kqrl3rv	482	7	the	the	DT
cord-347298-7kqrl3rv	482	8	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	482	9	cell	cell	NN
cord-347298-7kqrl3rv	482	10	to	to	TO
cord-347298-7kqrl3rv	482	11	maintain	maintain	VB
cord-347298-7kqrl3rv	482	12	contact	contact	NN
cord-347298-7kqrl3rv	482	13	with	with	IN
cord-347298-7kqrl3rv	482	14	other	other	JJ
cord-347298-7kqrl3rv	482	15	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	482	16	cells	cell	NNS
cord-347298-7kqrl3rv	482	17	and	and	CC
cord-347298-7kqrl3rv	482	18	the	the	DT
cord-347298-7kqrl3rv	482	19	developing	develop	VBG
cord-347298-7kqrl3rv	482	20	germ	germ	NN
cord-347298-7kqrl3rv	482	21	cells	cell	NNS
cord-347298-7kqrl3rv	482	22	,	,	,
cord-347298-7kqrl3rv	482	23	by	by	IN
cord-347298-7kqrl3rv	482	24	altering	alter	VBG
cord-347298-7kqrl3rv	482	25	the	the	DT
cord-347298-7kqrl3rv	482	26	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	482	27	cell	cell	NN
cord-347298-7kqrl3rv	482	28	cytoskeleton	cytoskeleton	NN
cord-347298-7kqrl3rv	482	29	(	(	-LRB-
cord-347298-7kqrl3rv	482	30	Sarkar	Sarkar	NNP
cord-347298-7kqrl3rv	482	31	et	et	FW
cord-347298-7kqrl3rv	482	32	al	al	NNP
cord-347298-7kqrl3rv	482	33	.	.	NNP
cord-347298-7kqrl3rv	482	34	2008	2008	CD
cord-347298-7kqrl3rv	482	35	)	)	-RRB-
cord-347298-7kqrl3rv	482	36	.	.	.
cord-347298-7kqrl3rv	483	1	In	in	IN
cord-347298-7kqrl3rv	483	2	the	the	DT
cord-347298-7kqrl3rv	483	3	interstitium	interstitium	NN
cord-347298-7kqrl3rv	483	4	,	,	,
cord-347298-7kqrl3rv	483	5	both	both	CC
cord-347298-7kqrl3rv	483	6	IL1	IL1	NNP
cord-347298-7kqrl3rv	483	7	and	and	CC
cord-347298-7kqrl3rv	483	8	IL1	IL1	NNP
cord-347298-7kqrl3rv	483	9	suppress	suppress	VBP
cord-347298-7kqrl3rv	483	10	LH	LH	NNP
cord-347298-7kqrl3rv	483	11	-	-	HYPH
cord-347298-7kqrl3rv	483	12	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	483	13	androgen	androgen	NN
cord-347298-7kqrl3rv	483	14	production	production	NN
cord-347298-7kqrl3rv	483	15	by	by	IN
cord-347298-7kqrl3rv	483	16	adult	adult	NN
cord-347298-7kqrl3rv	483	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	483	18	cells	cell	NNS
cord-347298-7kqrl3rv	483	19	through	through	IN
cord-347298-7kqrl3rv	483	20	inhibition	inhibition	NN
cord-347298-7kqrl3rv	483	21	of	of	IN
cord-347298-7kqrl3rv	483	22	steroidogenic	steroidogenic	NNP
cord-347298-7kqrl3rv	483	23	enzyme	enzyme	NN
cord-347298-7kqrl3rv	483	24	activity	activity	NN
cord-347298-7kqrl3rv	483	25	(	(	-LRB-
cord-347298-7kqrl3rv	483	26	Hales	Hales	NNP
cord-347298-7kqrl3rv	483	27	1992	1992	CD
cord-347298-7kqrl3rv	483	28	;	;	:
cord-347298-7kqrl3rv	483	29	Hales	Hales	NNP
cord-347298-7kqrl3rv	483	30	1994	1994	CD
cord-347298-7kqrl3rv	483	31	,	,	,
cord-347298-7kqrl3rv	483	32	1997	1997	CD
cord-347298-7kqrl3rv	483	33	)	)	-RRB-
cord-347298-7kqrl3rv	483	34	.	.	.
cord-347298-7kqrl3rv	484	1	IL1ra	IL1ra	NNP
cord-347298-7kqrl3rv	484	2	is	be	VBZ
cord-347298-7kqrl3rv	484	3	produced	produce	VBN
cord-347298-7kqrl3rv	484	4	by	by	IN
cord-347298-7kqrl3rv	484	5	the	the	DT
cord-347298-7kqrl3rv	484	6	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	484	7	cell	cell	NN
cord-347298-7kqrl3rv	484	8	,	,	,
cord-347298-7kqrl3rv	484	9	and	and	CC
cord-347298-7kqrl3rv	484	10	is	be	VBZ
cord-347298-7kqrl3rv	484	11	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	484	12	by	by	IN
cord-347298-7kqrl3rv	484	13	FSH	fsh	NN
cord-347298-7kqrl3rv	484	14	,	,	,
cord-347298-7kqrl3rv	484	15	IL1	IL1	NNP
cord-347298-7kqrl3rv	484	16	,	,	,
cord-347298-7kqrl3rv	484	17	and	and	CC
cord-347298-7kqrl3rv	484	18	LPS	LPS	NNP
cord-347298-7kqrl3rv	484	19	(	(	-LRB-
cord-347298-7kqrl3rv	484	20	Zeyse	Zeyse	NNP
cord-347298-7kqrl3rv	484	21	et	et	FW
cord-347298-7kqrl3rv	484	22	al	al	NNP
cord-347298-7kqrl3rv	484	23	.	.	.
cord-347298-7kqrl3rv	484	24	2000	2000	CD
cord-347298-7kqrl3rv	484	25	)	)	-RRB-
cord-347298-7kqrl3rv	484	26	.	.	.
cord-347298-7kqrl3rv	485	1	Presumably	presumably	RB
cord-347298-7kqrl3rv	485	2	,	,	,
cord-347298-7kqrl3rv	485	3	its	-PRON-	PRP$
cord-347298-7kqrl3rv	485	4	role	role	NN
cord-347298-7kqrl3rv	485	5	is	be	VBZ
cord-347298-7kqrl3rv	485	6	to	to	TO
cord-347298-7kqrl3rv	485	7	regulate	regulate	VB
cord-347298-7kqrl3rv	485	8	the	the	DT
cord-347298-7kqrl3rv	485	9	activity	activity	NN
cord-347298-7kqrl3rv	485	10	of	of	IN
cord-347298-7kqrl3rv	485	11	IL1/	IL1/	NNP
cord-347298-7kqrl3rv	485	12	within	within	IN
cord-347298-7kqrl3rv	485	13	the	the	DT
cord-347298-7kqrl3rv	485	14	testis	testis	NN
cord-347298-7kqrl3rv	485	15	.	.	.
cord-347298-7kqrl3rv	486	1	Both	both	CC
cord-347298-7kqrl3rv	486	2	IL18	IL18	NNP
cord-347298-7kqrl3rv	486	3	and	and	CC
cord-347298-7kqrl3rv	486	4	its	-PRON-	PRP$
cord-347298-7kqrl3rv	486	5	receptor	receptor	NN
cord-347298-7kqrl3rv	486	6	have	have	VBP
cord-347298-7kqrl3rv	486	7	been	be	VBN
cord-347298-7kqrl3rv	486	8	found	find	VBN
cord-347298-7kqrl3rv	486	9	in	in	IN
cord-347298-7kqrl3rv	486	10	the	the	DT
cord-347298-7kqrl3rv	486	11	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	486	12	epithelium	epithelium	NN
cord-347298-7kqrl3rv	486	13	,	,	,
cord-347298-7kqrl3rv	486	14	with	with	IN
cord-347298-7kqrl3rv	486	15	IL18	IL18	NNP
cord-347298-7kqrl3rv	486	16	mRNA	mRNA	NNP
cord-347298-7kqrl3rv	486	17	and	and	CC
cord-347298-7kqrl3rv	486	18	protein	protein	NN
cord-347298-7kqrl3rv	486	19	localized	localize	VBN
cord-347298-7kqrl3rv	486	20	to	to	IN
cord-347298-7kqrl3rv	486	21	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	486	22	and	and	CC
cord-347298-7kqrl3rv	486	23	round	round	JJ
cord-347298-7kqrl3rv	486	24	spermatids	spermatid	NNS
cord-347298-7kqrl3rv	487	1	(	(	-LRB-
cord-347298-7kqrl3rv	487	2	Strand	strand	NN
cord-347298-7kqrl3rv	487	3	et	et	FW
cord-347298-7kqrl3rv	487	4	al	al	NNP
cord-347298-7kqrl3rv	487	5	.	.	NNP
cord-347298-7kqrl3rv	487	6	2005	2005	CD
cord-347298-7kqrl3rv	487	7	)	)	-RRB-
cord-347298-7kqrl3rv	487	8	.	.	.
cord-347298-7kqrl3rv	488	1	As	as	IN
cord-347298-7kqrl3rv	488	2	is	be	VBZ
cord-347298-7kqrl3rv	488	3	the	the	DT
cord-347298-7kqrl3rv	488	4	case	case	NN
cord-347298-7kqrl3rv	488	5	for	for	IN
cord-347298-7kqrl3rv	488	6	IL1	IL1	NNP
cord-347298-7kqrl3rv	488	7	,	,	,
cord-347298-7kqrl3rv	488	8	the	the	DT
cord-347298-7kqrl3rv	488	9	majority	majority	NN
cord-347298-7kqrl3rv	488	10	of	of	IN
cord-347298-7kqrl3rv	488	11	IL18	IL18	NNP
cord-347298-7kqrl3rv	488	12	produced	produce	VBN
cord-347298-7kqrl3rv	488	13	within	within	IN
cord-347298-7kqrl3rv	488	14	the	the	DT
cord-347298-7kqrl3rv	488	15	testis	testis	NN
cord-347298-7kqrl3rv	488	16	is	be	VBZ
cord-347298-7kqrl3rv	488	17	in	in	IN
cord-347298-7kqrl3rv	488	18	the	the	DT
cord-347298-7kqrl3rv	488	19	precursor	precursor	NN
cord-347298-7kqrl3rv	488	20	form	form	NN
cord-347298-7kqrl3rv	488	21	,	,	,
cord-347298-7kqrl3rv	488	22	indicating	indicate	VBG
cord-347298-7kqrl3rv	488	23	that	that	IN
cord-347298-7kqrl3rv	488	24	the	the	DT
cord-347298-7kqrl3rv	488	25	processing	processing	NN
cord-347298-7kqrl3rv	488	26	of	of	IN
cord-347298-7kqrl3rv	488	27	these	these	DT
cord-347298-7kqrl3rv	488	28	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	488	29	by	by	IN
cord-347298-7kqrl3rv	488	30	caspase	caspase	NN
cord-347298-7kqrl3rv	488	31	1	1	CD
cord-347298-7kqrl3rv	488	32	in	in	IN
cord-347298-7kqrl3rv	488	33	the	the	DT
cord-347298-7kqrl3rv	488	34	testis	testis	NN
cord-347298-7kqrl3rv	488	35	is	be	VBZ
cord-347298-7kqrl3rv	488	36	an	an	DT
cord-347298-7kqrl3rv	488	37	area	area	NN
cord-347298-7kqrl3rv	488	38	requiring	require	VBG
cord-347298-7kqrl3rv	488	39	more	more	JJR
cord-347298-7kqrl3rv	488	40	investigation	investigation	NN
cord-347298-7kqrl3rv	488	41	.	.	.
cord-347298-7kqrl3rv	489	1	IL18	IL18	NNP
cord-347298-7kqrl3rv	489	2	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	489	3	spermatogonial	spermatogonial	JJ
cord-347298-7kqrl3rv	489	4	DNA	dna	NN
cord-347298-7kqrl3rv	489	5	synthesis	synthesis	NN
cord-347298-7kqrl3rv	489	6	in	in	IN
cord-347298-7kqrl3rv	489	7	cultures	culture	NNS
cord-347298-7kqrl3rv	489	8	of	of	IN
cord-347298-7kqrl3rv	489	9	rat	rat	NN
cord-347298-7kqrl3rv	489	10	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	489	11	tubules	tubule	NNS
cord-347298-7kqrl3rv	489	12	,	,	,
cord-347298-7kqrl3rv	489	13	without	without	IN
cord-347298-7kqrl3rv	489	14	influencing	influence	VBG
cord-347298-7kqrl3rv	489	15	germ	germ	NN
cord-347298-7kqrl3rv	489	16	cell	cell	NN
cord-347298-7kqrl3rv	489	17	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	489	18	(	(	-LRB-
cord-347298-7kqrl3rv	489	19	Strand	strand	NN
cord-347298-7kqrl3rv	489	20	et	et	FW
cord-347298-7kqrl3rv	489	21	al	al	NNP
cord-347298-7kqrl3rv	489	22	.	.	NNP
cord-347298-7kqrl3rv	489	23	2005	2005	CD
cord-347298-7kqrl3rv	489	24	)	)	-RRB-
cord-347298-7kqrl3rv	489	25	.	.	.
cord-347298-7kqrl3rv	490	1	Another	another	DT
cord-347298-7kqrl3rv	490	2	member	member	NN
cord-347298-7kqrl3rv	490	3	of	of	IN
cord-347298-7kqrl3rv	490	4	the	the	DT
cord-347298-7kqrl3rv	490	5	family	family	NN
cord-347298-7kqrl3rv	490	6	localized	localize	VBN
cord-347298-7kqrl3rv	490	7	to	to	IN
cord-347298-7kqrl3rv	490	8	the	the	DT
cord-347298-7kqrl3rv	490	9	testis	testis	NN
cord-347298-7kqrl3rv	490	10	is	be	VBZ
cord-347298-7kqrl3rv	490	11	IL1F8	il1f8	NN
cord-347298-7kqrl3rv	490	12	,	,	,
cord-347298-7kqrl3rv	490	13	although	although	IN
cord-347298-7kqrl3rv	490	14	its	-PRON-	PRP$
cord-347298-7kqrl3rv	490	15	function	function	NN
cord-347298-7kqrl3rv	490	16	there	there	EX
cord-347298-7kqrl3rv	490	17	is	be	VBZ
cord-347298-7kqrl3rv	490	18	entirely	entirely	RB
cord-347298-7kqrl3rv	490	19	unknown	unknown	JJ
cord-347298-7kqrl3rv	490	20	(	(	-LRB-
cord-347298-7kqrl3rv	490	21	Kumar	Kumar	NNP
cord-347298-7kqrl3rv	490	22	et	et	NNP
cord-347298-7kqrl3rv	490	23	al	al	NNP
cord-347298-7kqrl3rv	490	24	.	.	.
cord-347298-7kqrl3rv	490	25	2000	2000	CD
cord-347298-7kqrl3rv	490	26	)	)	-RRB-
cord-347298-7kqrl3rv	490	27	.	.	.
cord-347298-7kqrl3rv	491	1	.10.4.2.3	.10.4.2.3	.
cord-347298-7kqrl3rv	492	1	Tumor	tumor	NN
cord-347298-7kqrl3rv	492	2	necrosis	necrosis	NN
cord-347298-7kqrl3rv	492	3	factor	factor	NN
cord-347298-7kqrl3rv	492	4	and	and	CC
cord-347298-7kqrl3rv	493	1	Fas	Fas	NNP
cord-347298-7kqrl3rv	493	2	ligand	ligand	NN
cord-347298-7kqrl3rv	493	3	TNF	TNF	NNP
cord-347298-7kqrl3rv	493	4	and	and	CC
cord-347298-7kqrl3rv	493	5	FasL	FasL	NNP
cord-347298-7kqrl3rv	493	6	are	be	VBP
cord-347298-7kqrl3rv	493	7	transmembrane	transmembrane	JJ
cord-347298-7kqrl3rv	493	8	and	and	CC
cord-347298-7kqrl3rv	493	9	secreted	secrete	VBN
cord-347298-7kqrl3rv	493	10	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	493	11	with	with	IN
cord-347298-7kqrl3rv	493	12	typically	typically	RB
cord-347298-7kqrl3rv	493	13	trimeric	trimeric	JJ
cord-347298-7kqrl3rv	493	14	structures	structure	NNS
cord-347298-7kqrl3rv	493	15	and	and	CC
cord-347298-7kqrl3rv	493	16	they	-PRON-	PRP
cord-347298-7kqrl3rv	493	17	interact	interact	VBP
cord-347298-7kqrl3rv	493	18	with	with	IN
cord-347298-7kqrl3rv	493	19	specific	specific	JJ
cord-347298-7kqrl3rv	493	20	receptors	receptor	NNS
cord-347298-7kqrl3rv	493	21	to	to	TO
cord-347298-7kqrl3rv	493	22	mediate	mediate	VB
cord-347298-7kqrl3rv	493	23	a	a	DT
cord-347298-7kqrl3rv	493	24	cell	cell	NN
cord-347298-7kqrl3rv	493	25	death	death	NN
cord-347298-7kqrl3rv	493	26	signal	signal	NN
cord-347298-7kqrl3rv	493	27	(	(	-LRB-
cord-347298-7kqrl3rv	493	28	Ju	Ju	NNP
cord-347298-7kqrl3rv	493	29	et	et	NNP
cord-347298-7kqrl3rv	493	30	al	al	NNP
cord-347298-7kqrl3rv	493	31	.	.	NNP
cord-347298-7kqrl3rv	493	32	1995	1995	CD
cord-347298-7kqrl3rv	493	33	;	;	:
cord-347298-7kqrl3rv	494	1	Schütze	Schütze	NNP
cord-347298-7kqrl3rv	494	2	et	et	NNP
cord-347298-7kqrl3rv	494	3	al	al	NNP
cord-347298-7kqrl3rv	494	4	.	.	NNP
cord-347298-7kqrl3rv	494	5	2008	2008	CD
cord-347298-7kqrl3rv	494	6	)	)	-RRB-
cord-347298-7kqrl3rv	494	7	.	.	.
cord-347298-7kqrl3rv	495	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	495	2	are	be	VBP
cord-347298-7kqrl3rv	495	3	implicated	implicate	VBN
cord-347298-7kqrl3rv	495	4	in	in	IN
cord-347298-7kqrl3rv	495	5	both	both	DT
cord-347298-7kqrl3rv	495	6	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	495	7	and	and	CC
cord-347298-7kqrl3rv	495	8	the	the	DT
cord-347298-7kqrl3rv	495	9	control	control	NN
cord-347298-7kqrl3rv	495	10	of	of	IN
cord-347298-7kqrl3rv	495	11	normal	normal	JJ
cord-347298-7kqrl3rv	495	12	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	495	13	function	function	NN
cord-347298-7kqrl3rv	495	14	in	in	IN
cord-347298-7kqrl3rv	495	15	the	the	DT
cord-347298-7kqrl3rv	495	16	testis	testis	NN
cord-347298-7kqrl3rv	495	17	.	.	.
cord-347298-7kqrl3rv	496	1	TNF	TNF	NNP
cord-347298-7kqrl3rv	496	2	is	be	VBZ
cord-347298-7kqrl3rv	496	3	a	a	DT
cord-347298-7kqrl3rv	496	4	17	17	CD
cord-347298-7kqrl3rv	496	5	kDa	kDa	NNS
cord-347298-7kqrl3rv	496	6	glycosylated	glycosylate	VBN
cord-347298-7kqrl3rv	496	7	polypeptide	polypeptide	NN
cord-347298-7kqrl3rv	496	8	and	and	CC
cord-347298-7kqrl3rv	496	9	is	be	VBZ
cord-347298-7kqrl3rv	496	10	a	a	DT
cord-347298-7kqrl3rv	496	11	major	major	JJ
cord-347298-7kqrl3rv	496	12	early	early	JJ
cord-347298-7kqrl3rv	496	13	product	product	NN
cord-347298-7kqrl3rv	496	14	of	of	IN
cord-347298-7kqrl3rv	496	15	activated	activate	VBN
cord-347298-7kqrl3rv	496	16	monocytes	monocyte	NNS
cord-347298-7kqrl3rv	496	17	and	and	CC
cord-347298-7kqrl3rv	496	18	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	496	19	.	.	.
cord-347298-7kqrl3rv	497	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	497	2	binds	bind	VBZ
cord-347298-7kqrl3rv	497	3	to	to	IN
cord-347298-7kqrl3rv	497	4	either	either	DT
cord-347298-7kqrl3rv	497	5	of	of	IN
cord-347298-7kqrl3rv	497	6	two	two	CD
cord-347298-7kqrl3rv	497	7	TNF	TNF	NNP
cord-347298-7kqrl3rv	497	8	receptor	receptor	NN
cord-347298-7kqrl3rv	497	9	subsets	subset	NNS
cord-347298-7kqrl3rv	497	10	(	(	-LRB-
cord-347298-7kqrl3rv	497	11	TNFR1	tnfr1	XX
cord-347298-7kqrl3rv	497	12	and	and	CC
cord-347298-7kqrl3rv	497	13	TNFR2	TNFR2	NNP
cord-347298-7kqrl3rv	497	14	)	)	-RRB-
cord-347298-7kqrl3rv	497	15	and	and	CC
cord-347298-7kqrl3rv	497	16	plays	play	VBZ
cord-347298-7kqrl3rv	497	17	a	a	DT
cord-347298-7kqrl3rv	497	18	central	central	JJ
cord-347298-7kqrl3rv	497	19	role	role	NN
cord-347298-7kqrl3rv	497	20	in	in	IN
cord-347298-7kqrl3rv	497	21	initiating	initiate	VBG
cord-347298-7kqrl3rv	497	22	the	the	DT
cord-347298-7kqrl3rv	497	23	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	497	24	response	response	NN
cord-347298-7kqrl3rv	497	25	by	by	IN
cord-347298-7kqrl3rv	497	26	stimulating	stimulate	VBG
cord-347298-7kqrl3rv	497	27	the	the	DT
cord-347298-7kqrl3rv	497	28	production	production	NN
cord-347298-7kqrl3rv	497	29	of	of	IN
cord-347298-7kqrl3rv	497	30	IL1	IL1	NNP
cord-347298-7kqrl3rv	497	31	and	and	CC
cord-347298-7kqrl3rv	497	32	IL6	IL6	NNP
cord-347298-7kqrl3rv	497	33	(	(	-LRB-
cord-347298-7kqrl3rv	497	34	Basak	Basak	NNP
cord-347298-7kqrl3rv	497	35	and	and	CC
cord-347298-7kqrl3rv	497	36	Hoffmann	Hoffmann	NNP
cord-347298-7kqrl3rv	497	37	2008	2008	CD
cord-347298-7kqrl3rv	497	38	;	;	:
cord-347298-7kqrl3rv	497	39	Bradley	Bradley	NNP
cord-347298-7kqrl3rv	497	40	2008	2008	CD
cord-347298-7kqrl3rv	497	41	)	)	-RRB-
cord-347298-7kqrl3rv	497	42	.	.	.
cord-347298-7kqrl3rv	498	1	Whether	whether	IN
cord-347298-7kqrl3rv	498	2	TNF	TNF	NNP
cord-347298-7kqrl3rv	498	3	exerts	exert	VBZ
cord-347298-7kqrl3rv	498	4	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	498	5	or	or	CC
cord-347298-7kqrl3rv	498	6	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	498	7	effects	effect	NNS
cord-347298-7kqrl3rv	498	8	depends	depend	VBZ
cord-347298-7kqrl3rv	498	9	on	on	IN
cord-347298-7kqrl3rv	498	10	the	the	DT
cord-347298-7kqrl3rv	498	11	receptor	receptor	NN
cord-347298-7kqrl3rv	498	12	subtype	subtype	NN
cord-347298-7kqrl3rv	498	13	engaged	engage	VBN
cord-347298-7kqrl3rv	498	14	and	and	CC
cord-347298-7kqrl3rv	498	15	the	the	DT
cord-347298-7kqrl3rv	498	16	expression	expression	NN
cord-347298-7kqrl3rv	498	17	of	of	IN
cord-347298-7kqrl3rv	498	18	specific	specific	JJ
cord-347298-7kqrl3rv	498	19	adaptor	adaptor	NN
cord-347298-7kqrl3rv	498	20	proteins	protein	NNS
cord-347298-7kqrl3rv	498	21	within	within	IN
cord-347298-7kqrl3rv	498	22	the	the	DT
cord-347298-7kqrl3rv	498	23	target	target	NN
cord-347298-7kqrl3rv	498	24	cell	cell	NN
cord-347298-7kqrl3rv	498	25	(	(	-LRB-
cord-347298-7kqrl3rv	498	26	Basak	Basak	NNP
cord-347298-7kqrl3rv	498	27	and	and	CC
cord-347298-7kqrl3rv	498	28	Hoffmann	Hoffmann	NNP
cord-347298-7kqrl3rv	498	29	2008	2008	CD
cord-347298-7kqrl3rv	498	30	;	;	:
cord-347298-7kqrl3rv	498	31	Chung	Chung	NNP
cord-347298-7kqrl3rv	498	32	et	et	NNP
cord-347298-7kqrl3rv	498	33	al	al	NNP
cord-347298-7kqrl3rv	498	34	.	.	.
cord-347298-7kqrl3rv	498	35	2002	2002	CD
cord-347298-7kqrl3rv	498	36	;	;	:
cord-347298-7kqrl3rv	498	37	Hsu	Hsu	NNP
cord-347298-7kqrl3rv	498	38	et	et	NNP
cord-347298-7kqrl3rv	498	39	al	al	NNP
cord-347298-7kqrl3rv	498	40	.	.	.
cord-347298-7kqrl3rv	499	1	1996	1996	CD
cord-347298-7kqrl3rv	500	1	;	;	:
cord-347298-7kqrl3rv	500	2	Mak	Mak	NNP
cord-347298-7kqrl3rv	500	3	and	and	CC
cord-347298-7kqrl3rv	500	4	Yeh	Yeh	NNP
cord-347298-7kqrl3rv	500	5	2002	2002	CD
cord-347298-7kqrl3rv	500	6	)	)	-RRB-
cord-347298-7kqrl3rv	500	7	.	.	.
cord-347298-7kqrl3rv	501	1	Consistent	consistent	JJ
cord-347298-7kqrl3rv	501	2	with	with	IN
cord-347298-7kqrl3rv	501	3	its	-PRON-	PRP$
cord-347298-7kqrl3rv	501	4	name	name	NN
cord-347298-7kqrl3rv	501	5	,	,	,
cord-347298-7kqrl3rv	501	6	TNF	TNF	NNP
cord-347298-7kqrl3rv	501	7	exerts	exert	VBZ
cord-347298-7kqrl3rv	501	8	a	a	DT
cord-347298-7kqrl3rv	501	9	cell	cell	NN
cord-347298-7kqrl3rv	501	10	death	death	NN
cord-347298-7kqrl3rv	501	11	signal	signal	NN
cord-347298-7kqrl3rv	501	12	via	via	IN
cord-347298-7kqrl3rv	501	13	TNFR1	TNFR1	NNP
cord-347298-7kqrl3rv	501	14	,	,	,
cord-347298-7kqrl3rv	501	15	through	through	IN
cord-347298-7kqrl3rv	501	16	interaction	interaction	NN
cord-347298-7kqrl3rv	501	17	with	with	IN
cord-347298-7kqrl3rv	501	18	the	the	DT
cord-347298-7kqrl3rv	501	19	TNFR	TNFR	NNP
cord-347298-7kqrl3rv	501	20	-	-	HYPH
cord-347298-7kqrl3rv	501	21	associated	associate	VBN
cord-347298-7kqrl3rv	501	22	death	death	NN
cord-347298-7kqrl3rv	501	23	domain	domain	NN
cord-347298-7kqrl3rv	501	24	protein	protein	NN
cord-347298-7kqrl3rv	501	25	(	(	-LRB-
cord-347298-7kqrl3rv	501	26	TRADD	TRADD	NNP
cord-347298-7kqrl3rv	501	27	)	)	-RRB-
cord-347298-7kqrl3rv	501	28	or	or	CC
cord-347298-7kqrl3rv	501	29	the	the	DT
cord-347298-7kqrl3rv	501	30	Fas	Fas	NNP
cord-347298-7kqrl3rv	501	31	-	-	HYPH
cord-347298-7kqrl3rv	501	32	associated	associate	VBN
cord-347298-7kqrl3rv	501	33	death	death	NN
cord-347298-7kqrl3rv	501	34	domain	domain	NN
cord-347298-7kqrl3rv	501	35	protein	protein	NN
cord-347298-7kqrl3rv	501	36	(	(	-LRB-
cord-347298-7kqrl3rv	501	37	FADD	FADD	NNP
cord-347298-7kqrl3rv	501	38	)	)	-RRB-
cord-347298-7kqrl3rv	501	39	,	,	,
cord-347298-7kqrl3rv	501	40	and	and	CC
cord-347298-7kqrl3rv	501	41	activation	activation	NN
cord-347298-7kqrl3rv	501	42	of	of	IN
cord-347298-7kqrl3rv	501	43	the	the	DT
cord-347298-7kqrl3rv	501	44	caspase	caspase	NN
cord-347298-7kqrl3rv	501	45	-	-	HYPH
cord-347298-7kqrl3rv	501	46	dependent	dependent	JJ
cord-347298-7kqrl3rv	501	47	apoptotic	apoptotic	JJ
cord-347298-7kqrl3rv	501	48	pathway	pathway	NN
cord-347298-7kqrl3rv	501	49	(	(	-LRB-
cord-347298-7kqrl3rv	501	50	Schütze	Schütze	NNP
cord-347298-7kqrl3rv	501	51	et	et	NNP
cord-347298-7kqrl3rv	501	52	al	al	NNP
cord-347298-7kqrl3rv	501	53	.	.	NNP
cord-347298-7kqrl3rv	501	54	2008	2008	CD
cord-347298-7kqrl3rv	501	55	)	)	-RRB-
cord-347298-7kqrl3rv	501	56	.	.	.
cord-347298-7kqrl3rv	502	1	However	however	RB
cord-347298-7kqrl3rv	502	2	,	,	,
cord-347298-7kqrl3rv	502	3	interaction	interaction	NN
cord-347298-7kqrl3rv	502	4	with	with	IN
cord-347298-7kqrl3rv	502	5	TRADD	TRADD	NNP
cord-347298-7kqrl3rv	502	6	can	can	MD
cord-347298-7kqrl3rv	502	7	also	also	RB
cord-347298-7kqrl3rv	502	8	result	result	VB
cord-347298-7kqrl3rv	502	9	in	in	IN
cord-347298-7kqrl3rv	502	10	recruitment	recruitment	NN
cord-347298-7kqrl3rv	502	11	of	of	IN
cord-347298-7kqrl3rv	502	12	other	other	JJ
cord-347298-7kqrl3rv	502	13	adaptor	adaptor	NN
cord-347298-7kqrl3rv	502	14	proteins	protein	NNS
cord-347298-7kqrl3rv	502	15	leading	lead	VBG
cord-347298-7kqrl3rv	502	16	to	to	IN
cord-347298-7kqrl3rv	502	17	the	the	DT
cord-347298-7kqrl3rv	502	18	binding	binding	NN
cord-347298-7kqrl3rv	502	19	of	of	IN
cord-347298-7kqrl3rv	502	20	TRAF2	traf2	NN
cord-347298-7kqrl3rv	502	21	and	and	CC
cord-347298-7kqrl3rv	502	22	activation	activation	NN
cord-347298-7kqrl3rv	502	23	of	of	IN
cord-347298-7kqrl3rv	502	24	the	the	DT
cord-347298-7kqrl3rv	502	25	NFB	NFB	NNP
cord-347298-7kqrl3rv	502	26	pathway	pathway	NN
cord-347298-7kqrl3rv	502	27	and/or	and/or	CC
cord-347298-7kqrl3rv	503	1	the	the	DT
cord-347298-7kqrl3rv	503	2	MAP	MAP	NNP
cord-347298-7kqrl3rv	503	3	kinases	kinase	NNS
cord-347298-7kqrl3rv	503	4	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	503	5	or	or	CC
cord-347298-7kqrl3rv	503	6	p38	p38	NN
cord-347298-7kqrl3rv	503	7	(	(	-LRB-
cord-347298-7kqrl3rv	503	8	Chung	Chung	NNP
cord-347298-7kqrl3rv	503	9	et	et	NNP
cord-347298-7kqrl3rv	503	10	al	al	NNP
cord-347298-7kqrl3rv	503	11	.	.	.
cord-347298-7kqrl3rv	503	12	2002	2002	CD
cord-347298-7kqrl3rv	503	13	)	)	-RRB-
cord-347298-7kqrl3rv	503	14	.	.	.
cord-347298-7kqrl3rv	504	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	504	2	,	,	,
cord-347298-7kqrl3rv	504	3	TNFR2	tnfr2	NN
cord-347298-7kqrl3rv	504	4	and	and	CC
cord-347298-7kqrl3rv	504	5	its	-PRON-	PRP$
cord-347298-7kqrl3rv	504	6	related	related	JJ
cord-347298-7kqrl3rv	504	7	receptors	receptor	NNS
cord-347298-7kqrl3rv	504	8	,	,	,
cord-347298-7kqrl3rv	504	9	which	which	WDT
cord-347298-7kqrl3rv	504	10	include	include	VBP
cord-347298-7kqrl3rv	504	11	CD40	CD40	NNP
cord-347298-7kqrl3rv	504	12	,	,	,
cord-347298-7kqrl3rv	504	13	do	do	VBP
cord-347298-7kqrl3rv	504	14	not	not	RB
cord-347298-7kqrl3rv	504	15	contain	contain	VB
cord-347298-7kqrl3rv	504	16	a	a	DT
cord-347298-7kqrl3rv	504	17	death	death	NN
cord-347298-7kqrl3rv	504	18	domain	domain	NN
cord-347298-7kqrl3rv	504	19	,	,	,
cord-347298-7kqrl3rv	504	20	and	and	CC
cord-347298-7kqrl3rv	504	21	instead	instead	RB
cord-347298-7kqrl3rv	504	22	associate	associate	VB
cord-347298-7kqrl3rv	504	23	with	with	IN
cord-347298-7kqrl3rv	504	24	the	the	DT
cord-347298-7kqrl3rv	504	25	TRAFs	TRAFs	NNPS
cord-347298-7kqrl3rv	504	26	leading	lead	VBG
cord-347298-7kqrl3rv	504	27	to	to	IN
cord-347298-7kqrl3rv	504	28	activation	activation	NN
cord-347298-7kqrl3rv	504	29	of	of	IN
cord-347298-7kqrl3rv	504	30	cell	cell	NN
cord-347298-7kqrl3rv	504	31	signaling	signal	VBG
cord-347298-7kqrl3rv	504	32	events	event	NNS
cord-347298-7kqrl3rv	504	33	(	(	-LRB-
cord-347298-7kqrl3rv	504	34	Bradley	Bradley	NNP
cord-347298-7kqrl3rv	504	35	2008	2008	CD
cord-347298-7kqrl3rv	504	36	;	;	:
cord-347298-7kqrl3rv	505	1	Mak	Mak	NNP
cord-347298-7kqrl3rv	505	2	and	and	CC
cord-347298-7kqrl3rv	505	3	Yeh	Yeh	NNP
cord-347298-7kqrl3rv	505	4	2002	2002	CD
cord-347298-7kqrl3rv	505	5	)	)	-RRB-
cord-347298-7kqrl3rv	505	6	.	.	.
cord-347298-7kqrl3rv	506	1	In	in	IN
cord-347298-7kqrl3rv	506	2	the	the	DT
cord-347298-7kqrl3rv	506	3	mouse	mouse	NN
cord-347298-7kqrl3rv	506	4	testis	testis	NN
cord-347298-7kqrl3rv	506	5	,	,	,
cord-347298-7kqrl3rv	506	6	TNF	TNF	NNP
cord-347298-7kqrl3rv	506	7	is	be	VBZ
cord-347298-7kqrl3rv	506	8	expressed	express	VBN
cord-347298-7kqrl3rv	506	9	by	by	IN
cord-347298-7kqrl3rv	506	10	round	round	JJ
cord-347298-7kqrl3rv	506	11	spermatids	spermatid	NNS
cord-347298-7kqrl3rv	506	12	,	,	,
cord-347298-7kqrl3rv	506	13	pachytene	pachytene	NNP
cord-347298-7kqrl3rv	506	14	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	506	15	,	,	,
cord-347298-7kqrl3rv	506	16	and	and	CC
cord-347298-7kqrl3rv	506	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	506	18	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	506	19	,	,	,
cord-347298-7kqrl3rv	506	20	and	and	CC
cord-347298-7kqrl3rv	506	21	mRNA	mrna	NN
cord-347298-7kqrl3rv	506	22	for	for	IN
cord-347298-7kqrl3rv	506	23	TNFR1	TNFR1	NNP
cord-347298-7kqrl3rv	506	24	has	have	VBZ
cord-347298-7kqrl3rv	506	25	been	be	VBN
cord-347298-7kqrl3rv	506	26	located	locate	VBN
cord-347298-7kqrl3rv	506	27	on	on	IN
cord-347298-7kqrl3rv	506	28	both	both	DT
cord-347298-7kqrl3rv	506	29	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	506	30	and	and	CC
cord-347298-7kqrl3rv	506	31	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	506	32	cells	cell	NNS
cord-347298-7kqrl3rv	506	33	.	.	.
cord-347298-7kqrl3rv	507	1	In	in	IN
cord-347298-7kqrl3rv	507	2	porcine	porcine	JJ
cord-347298-7kqrl3rv	507	3	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	507	4	cells	cell	NNS
cord-347298-7kqrl3rv	507	5	,	,	,
cord-347298-7kqrl3rv	507	6	TNF	TNF	NNP
cord-347298-7kqrl3rv	507	7	receptor	receptor	NN
cord-347298-7kqrl3rv	507	8	subunit	subunit	NN
cord-347298-7kqrl3rv	507	9	protein	protein	NN
cord-347298-7kqrl3rv	507	10	expression	expression	NN
cord-347298-7kqrl3rv	507	11	is	be	VBZ
cord-347298-7kqrl3rv	507	12	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	507	13	by	by	IN
cord-347298-7kqrl3rv	507	14	FSH	fsh	NN
cord-347298-7kqrl3rv	507	15	(	(	-LRB-
cord-347298-7kqrl3rv	507	16	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	507	17	et	et	NNP
cord-347298-7kqrl3rv	507	18	al	al	NNP
cord-347298-7kqrl3rv	507	19	.	.	.
cord-347298-7kqrl3rv	507	20	1996	1996	CD
cord-347298-7kqrl3rv	507	21	)	)	-RRB-
cord-347298-7kqrl3rv	507	22	.	.	.
cord-347298-7kqrl3rv	508	1	There	there	EX
cord-347298-7kqrl3rv	508	2	is	be	VBZ
cord-347298-7kqrl3rv	508	3	no	no	DT
cord-347298-7kqrl3rv	508	4	evidence	evidence	NN
cord-347298-7kqrl3rv	508	5	that	that	IN
cord-347298-7kqrl3rv	508	6	TNF	TNF	NNP
cord-347298-7kqrl3rv	508	7	is	be	VBZ
cord-347298-7kqrl3rv	508	8	produced	produce	VBN
cord-347298-7kqrl3rv	508	9	by	by	IN
cord-347298-7kqrl3rv	508	10	the	the	DT
cord-347298-7kqrl3rv	508	11	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	508	12	cell	cell	NN
cord-347298-7kqrl3rv	508	13	,	,	,
cord-347298-7kqrl3rv	508	14	but	but	CC
cord-347298-7kqrl3rv	508	15	expression	expression	NN
cord-347298-7kqrl3rv	508	16	of	of	IN
cord-347298-7kqrl3rv	508	17	TNF	TNF	NNP
cord-347298-7kqrl3rv	508	18	by	by	IN
cord-347298-7kqrl3rv	508	19	the	the	DT
cord-347298-7kqrl3rv	508	20	germ	germ	NN
cord-347298-7kqrl3rv	508	21	cells	cell	NNS
cord-347298-7kqrl3rv	508	22	within	within	IN
cord-347298-7kqrl3rv	508	23	the	the	DT
cord-347298-7kqrl3rv	508	24	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	508	25	epithelium	epithelium	NN
cord-347298-7kqrl3rv	508	26	,	,	,
cord-347298-7kqrl3rv	508	27	like	like	IN
cord-347298-7kqrl3rv	508	28	that	that	DT
cord-347298-7kqrl3rv	508	29	of	of	IN
cord-347298-7kqrl3rv	508	30	IL1	IL1	NNP
cord-347298-7kqrl3rv	508	31	and	and	CC
cord-347298-7kqrl3rv	508	32	IL6	IL6	NNP
cord-347298-7kqrl3rv	508	33	,	,	,
cord-347298-7kqrl3rv	508	34	is	be	VBZ
cord-347298-7kqrl3rv	508	35	cyclical	cyclical	JJ
cord-347298-7kqrl3rv	508	36	.	.	.
cord-347298-7kqrl3rv	509	1	Within	within	IN
cord-347298-7kqrl3rv	509	2	the	the	DT
cord-347298-7kqrl3rv	509	3	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	509	4	epithelium	epithelium	NN
cord-347298-7kqrl3rv	509	5	,	,	,
cord-347298-7kqrl3rv	509	6	TNF	TNF	NNP
cord-347298-7kqrl3rv	509	7	produced	produce	VBN
cord-347298-7kqrl3rv	509	8	by	by	IN
cord-347298-7kqrl3rv	509	9	the	the	DT
cord-347298-7kqrl3rv	509	10	germ	germ	NN
cord-347298-7kqrl3rv	509	11	cells	cell	NNS
cord-347298-7kqrl3rv	509	12	appears	appear	VBZ
cord-347298-7kqrl3rv	509	13	to	to	TO
cord-347298-7kqrl3rv	509	14	play	play	VB
cord-347298-7kqrl3rv	509	15	a	a	DT
cord-347298-7kqrl3rv	509	16	complex	complex	JJ
cord-347298-7kqrl3rv	509	17	role	role	NN
cord-347298-7kqrl3rv	509	18	in	in	IN
cord-347298-7kqrl3rv	509	19	the	the	DT
cord-347298-7kqrl3rv	509	20	control	control	NN
cord-347298-7kqrl3rv	509	21	of	of	IN
cord-347298-7kqrl3rv	509	22	both	both	DT
cord-347298-7kqrl3rv	509	23	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	509	24	cell	cell	NN
cord-347298-7kqrl3rv	509	25	function	function	NN
cord-347298-7kqrl3rv	509	26	and	and	CC
cord-347298-7kqrl3rv	509	27	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	509	28	.	.	.
cord-347298-7kqrl3rv	510	1	TNF	TNF	NNP
cord-347298-7kqrl3rv	510	2	reduces	reduce	VBZ
cord-347298-7kqrl3rv	510	3	spontaneous	spontaneous	JJ
cord-347298-7kqrl3rv	510	4	germ	germ	NN
cord-347298-7kqrl3rv	510	5	cell	cell	NN
cord-347298-7kqrl3rv	510	6	degeneration	degeneration	NN
cord-347298-7kqrl3rv	510	7	in	in	IN
cord-347298-7kqrl3rv	510	8	cultured	cultured	JJ
cord-347298-7kqrl3rv	510	9	human	human	NN
cord-347298-7kqrl3rv	510	10	and	and	CC
cord-347298-7kqrl3rv	510	11	rat	rat	NN
cord-347298-7kqrl3rv	510	12	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	510	13	tubules	tubule	NNS
cord-347298-7kqrl3rv	510	14	,	,	,
cord-347298-7kqrl3rv	510	15	suggesting	suggest	VBG
cord-347298-7kqrl3rv	510	16	a	a	DT
cord-347298-7kqrl3rv	510	17	germ	germ	NN
cord-347298-7kqrl3rv	510	18	cell	cell	NN
cord-347298-7kqrl3rv	510	19	survival	survival	NN
cord-347298-7kqrl3rv	510	20	effect	effect	NN
cord-347298-7kqrl3rv	510	21	presumably	presumably	RB
cord-347298-7kqrl3rv	510	22	mediated	mediate	VBD
cord-347298-7kqrl3rv	510	23	through	through	IN
cord-347298-7kqrl3rv	510	24	the	the	DT
cord-347298-7kqrl3rv	510	25	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	510	26	cell	cell	NN
cord-347298-7kqrl3rv	511	1	(	(	-LRB-
cord-347298-7kqrl3rv	511	2	Pentikäinen	Pentikäinen	NNP
cord-347298-7kqrl3rv	511	3	et	et	FW
cord-347298-7kqrl3rv	511	4	al	al	NNP
cord-347298-7kqrl3rv	511	5	.	.	.
cord-347298-7kqrl3rv	512	1	2001	2001	CD
cord-347298-7kqrl3rv	512	2	;	;	:
cord-347298-7kqrl3rv	512	3	Suominen	Suominen	NNP
cord-347298-7kqrl3rv	512	4	et	et	NNP
cord-347298-7kqrl3rv	512	5	al	al	NNP
cord-347298-7kqrl3rv	512	6	.	.	.
cord-347298-7kqrl3rv	512	7	2004	2004	CD
cord-347298-7kqrl3rv	512	8	)	)	-RRB-
cord-347298-7kqrl3rv	512	9	.	.	.
cord-347298-7kqrl3rv	513	1	Conversely	conversely	RB
cord-347298-7kqrl3rv	513	2	,	,	,
cord-347298-7kqrl3rv	513	3	TNF	TNF	NNP
cord-347298-7kqrl3rv	513	4	disrupts	disrupt	VBZ
cord-347298-7kqrl3rv	513	5	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	513	6	cell	cell	NN
cord-347298-7kqrl3rv	513	7	tight	tight	JJ
cord-347298-7kqrl3rv	513	8	junction	junction	NN
cord-347298-7kqrl3rv	513	9	assembly	assembly	NN
cord-347298-7kqrl3rv	513	10	by	by	IN
cord-347298-7kqrl3rv	513	11	inhibiting	inhibit	VBG
cord-347298-7kqrl3rv	513	12	the	the	DT
cord-347298-7kqrl3rv	513	13	production	production	NN
cord-347298-7kqrl3rv	513	14	of	of	IN
cord-347298-7kqrl3rv	513	15	junction	junction	NN
cord-347298-7kqrl3rv	513	16	proteins	protein	NNS
cord-347298-7kqrl3rv	513	17	and	and	CC
cord-347298-7kqrl3rv	513	18	by	by	IN
cord-347298-7kqrl3rv	513	19	regulating	regulate	VBG
cord-347298-7kqrl3rv	513	20	matrix	matrix	NN
cord-347298-7kqrl3rv	513	21	metalloprotease	metalloprotease	NN
cord-347298-7kqrl3rv	513	22	and	and	CC
cord-347298-7kqrl3rv	513	23	protease	protease	JJ
cord-347298-7kqrl3rv	513	24	inhibitor	inhibitor	NN
cord-347298-7kqrl3rv	513	25	activity	activity	NN
cord-347298-7kqrl3rv	514	1	(	(	-LRB-
cord-347298-7kqrl3rv	514	2	Siu	Siu	NNP
cord-347298-7kqrl3rv	514	3	et	et	NNP
cord-347298-7kqrl3rv	514	4	al	al	NNP
cord-347298-7kqrl3rv	514	5	.	.	NNP
cord-347298-7kqrl3rv	514	6	2003	2003	CD
cord-347298-7kqrl3rv	514	7	)	)	-RRB-
cord-347298-7kqrl3rv	514	8	.	.	.
cord-347298-7kqrl3rv	515	1	TNF	TNF	NNP
cord-347298-7kqrl3rv	515	2	also	also	RB
cord-347298-7kqrl3rv	515	3	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	515	4	plasminogen	plasminogen	NN
cord-347298-7kqrl3rv	515	5	activator	activator	NN
cord-347298-7kqrl3rv	515	6	inhibitor	inhibitor	NN
cord-347298-7kqrl3rv	515	7	expression	expression	NN
cord-347298-7kqrl3rv	515	8	in	in	IN
cord-347298-7kqrl3rv	515	9	rat	rat	NNP
cord-347298-7kqrl3rv	515	10	testicular	testicular	NNP
cord-347298-7kqrl3rv	515	11	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	515	12	cells	cell	NNS
cord-347298-7kqrl3rv	516	1	(	(	-LRB-
cord-347298-7kqrl3rv	516	2	Le	Le	NNP
cord-347298-7kqrl3rv	516	3	Magueresse	Magueresse	NNP
cord-347298-7kqrl3rv	516	4	-	-	HYPH
cord-347298-7kqrl3rv	516	5	Battistoni	Battistoni	NNP
cord-347298-7kqrl3rv	516	6	et	et	NNP
cord-347298-7kqrl3rv	516	7	al	al	NNP
cord-347298-7kqrl3rv	516	8	.	.	.
cord-347298-7kqrl3rv	516	9	1997	1997	CD
cord-347298-7kqrl3rv	516	10	)	)	-RRB-
cord-347298-7kqrl3rv	516	11	.	.	.
cord-347298-7kqrl3rv	517	1	Similar	similar	JJ
cord-347298-7kqrl3rv	517	2	to	to	IN
cord-347298-7kqrl3rv	517	3	IL1	IL1	NNP
cord-347298-7kqrl3rv	517	4	,	,	,
cord-347298-7kqrl3rv	517	5	TNF	TNF	NNP
cord-347298-7kqrl3rv	517	6	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	517	7	basal	basal	NN
cord-347298-7kqrl3rv	517	8	lactate	lactate	NN
cord-347298-7kqrl3rv	517	9	production	production	NN
cord-347298-7kqrl3rv	517	10	by	by	IN
cord-347298-7kqrl3rv	517	11	cultured	cultured	JJ
cord-347298-7kqrl3rv	517	12	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	517	13	cells	cell	NNS
cord-347298-7kqrl3rv	517	14	,	,	,
cord-347298-7kqrl3rv	517	15	but	but	CC
cord-347298-7kqrl3rv	517	16	TNF	TNF	NNP
cord-347298-7kqrl3rv	517	17	generally	generally	RB
cord-347298-7kqrl3rv	517	18	antagonizes	antagonize	VBZ
cord-347298-7kqrl3rv	517	19	the	the	DT
cord-347298-7kqrl3rv	517	20	actions	action	NNS
cord-347298-7kqrl3rv	517	21	of	of	IN
cord-347298-7kqrl3rv	517	22	FSH	fsh	NN
cord-347298-7kqrl3rv	517	23	on	on	IN
cord-347298-7kqrl3rv	517	24	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	517	25	cell	cell	NN
cord-347298-7kqrl3rv	517	26	function	function	NN
cord-347298-7kqrl3rv	517	27	,	,	,
cord-347298-7kqrl3rv	517	28	including	include	VBG
cord-347298-7kqrl3rv	517	29	the	the	DT
cord-347298-7kqrl3rv	517	30	stimulation	stimulation	NN
cord-347298-7kqrl3rv	517	31	of	of	IN
cord-347298-7kqrl3rv	517	32	aromatase	aromatase	NN
cord-347298-7kqrl3rv	517	33	activity	activity	NN
cord-347298-7kqrl3rv	517	34	and	and	CC
cord-347298-7kqrl3rv	517	35	lactate	lactate	NN
cord-347298-7kqrl3rv	517	36	production	production	NN
cord-347298-7kqrl3rv	518	1	(	(	-LRB-
cord-347298-7kqrl3rv	518	2	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	518	3	et	et	NNP
cord-347298-7kqrl3rv	518	4	al	al	NNP
cord-347298-7kqrl3rv	518	5	.	.	.
cord-347298-7kqrl3rv	518	6	1993	1993	CD
cord-347298-7kqrl3rv	519	1	;	;	:
cord-347298-7kqrl3rv	519	2	Nehar	Nehar	NNP
cord-347298-7kqrl3rv	519	3	et	et	NNP
cord-347298-7kqrl3rv	519	4	al	al	NNP
cord-347298-7kqrl3rv	519	5	.	.	.
cord-347298-7kqrl3rv	520	1	1997	1997	CD
cord-347298-7kqrl3rv	520	2	;	;	:
cord-347298-7kqrl3rv	520	3	Riera	Riera	NNP
cord-347298-7kqrl3rv	520	4	et	et	NNP
cord-347298-7kqrl3rv	520	5	al	al	NNP
cord-347298-7kqrl3rv	520	6	.	.	NNP
cord-347298-7kqrl3rv	520	7	2001	2001	CD
cord-347298-7kqrl3rv	520	8	)	)	-RRB-
cord-347298-7kqrl3rv	520	9	.	.	.
cord-347298-7kqrl3rv	521	1	However	however	RB
cord-347298-7kqrl3rv	521	2	,	,	,
cord-347298-7kqrl3rv	521	3	Delfino	Delfino	NNP
cord-347298-7kqrl3rv	521	4	et	et	NNP
cord-347298-7kqrl3rv	521	5	al	al	NNP
cord-347298-7kqrl3rv	521	6	.	.	.
cord-347298-7kqrl3rv	522	1	(	(	-LRB-
cord-347298-7kqrl3rv	522	2	2003	2003	CD
cord-347298-7kqrl3rv	522	3	)	)	-RRB-
cord-347298-7kqrl3rv	522	4	have	have	VBP
cord-347298-7kqrl3rv	522	5	shown	show	VBN
cord-347298-7kqrl3rv	522	6	that	that	IN
cord-347298-7kqrl3rv	522	7	TNF	TNF	NNP
cord-347298-7kqrl3rv	522	8	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	522	9	androgen	androgen	NN
cord-347298-7kqrl3rv	522	10	receptor	receptor	NN
cord-347298-7kqrl3rv	522	11	expression	expression	NN
cord-347298-7kqrl3rv	522	12	in	in	IN
cord-347298-7kqrl3rv	522	13	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	522	14	cells	cell	NNS
cord-347298-7kqrl3rv	522	15	via	via	IN
cord-347298-7kqrl3rv	522	16	upregulation	upregulation	NN
cord-347298-7kqrl3rv	522	17	of	of	IN
cord-347298-7kqrl3rv	522	18	NFB	NFB	NNP
cord-347298-7kqrl3rv	522	19	,	,	,
cord-347298-7kqrl3rv	522	20	which	which	WDT
cord-347298-7kqrl3rv	522	21	binds	bind	VBZ
cord-347298-7kqrl3rv	522	22	to	to	IN
cord-347298-7kqrl3rv	522	23	several	several	JJ
cord-347298-7kqrl3rv	522	24	enhancer	enhancer	NN
cord-347298-7kqrl3rv	522	25	motifs	motif	NNS
cord-347298-7kqrl3rv	522	26	in	in	IN
cord-347298-7kqrl3rv	522	27	the	the	DT
cord-347298-7kqrl3rv	522	28	androgen	androgen	NN
cord-347298-7kqrl3rv	522	29	receptor	receptor	NN
cord-347298-7kqrl3rv	522	30	promoter	promoter	NN
cord-347298-7kqrl3rv	522	31	.	.	.
cord-347298-7kqrl3rv	523	1	TNF	TNF	NNP
cord-347298-7kqrl3rv	523	2	also	also	RB
cord-347298-7kqrl3rv	523	3	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	523	4	the	the	DT
cord-347298-7kqrl3rv	523	5	expression	expression	NN
cord-347298-7kqrl3rv	523	6	of	of	IN
cord-347298-7kqrl3rv	523	7	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	523	8	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	523	9	,	,	,
cord-347298-7kqrl3rv	523	10	chemokines	chemokine	NNS
cord-347298-7kqrl3rv	523	11	,	,	,
cord-347298-7kqrl3rv	523	12	and	and	CC
cord-347298-7kqrl3rv	523	13	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	523	14	adhesion	adhesion	NN
cord-347298-7kqrl3rv	523	15	molecules	molecule	NNS
cord-347298-7kqrl3rv	523	16	in	in	IN
cord-347298-7kqrl3rv	523	17	both	both	DT
cord-347298-7kqrl3rv	523	18	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	523	19	cells	cell	NNS
cord-347298-7kqrl3rv	523	20	and	and	CC
cord-347298-7kqrl3rv	523	21	peritubular	peritubular	JJ
cord-347298-7kqrl3rv	523	22	cells	cell	NNS
cord-347298-7kqrl3rv	523	23	(	(	-LRB-
cord-347298-7kqrl3rv	523	24	Aubry	Aubry	NNP
cord-347298-7kqrl3rv	523	25	et	et	NNP
cord-347298-7kqrl3rv	523	26	al	al	NNP
cord-347298-7kqrl3rv	523	27	.	.	.
cord-347298-7kqrl3rv	523	28	2000	2000	CD
cord-347298-7kqrl3rv	523	29	;	;	:
cord-347298-7kqrl3rv	523	30	De	De	NNP
cord-347298-7kqrl3rv	523	31	Cesaris	Cesaris	NNP
cord-347298-7kqrl3rv	523	32	et	et	NNP
cord-347298-7kqrl3rv	523	33	al	al	NNP
cord-347298-7kqrl3rv	523	34	.	.	.
cord-347298-7kqrl3rv	523	35	1998	1998	CD
cord-347298-7kqrl3rv	523	36	;	;	:
cord-347298-7kqrl3rv	523	37	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	523	38	et	et	NNP
cord-347298-7kqrl3rv	523	39	al	al	NNP
cord-347298-7kqrl3rv	523	40	.	.	.
cord-347298-7kqrl3rv	523	41	1997	1997	CD
cord-347298-7kqrl3rv	523	42	)	)	-RRB-
cord-347298-7kqrl3rv	523	43	.	.	.
cord-347298-7kqrl3rv	524	1	In	in	IN
cord-347298-7kqrl3rv	524	2	testicular	testicular	JJ
cord-347298-7kqrl3rv	524	3	pathology	pathology	NN
cord-347298-7kqrl3rv	524	4	,	,	,
cord-347298-7kqrl3rv	524	5	TNF	TNF	NNP
cord-347298-7kqrl3rv	524	6	has	have	VBZ
cord-347298-7kqrl3rv	524	7	been	be	VBN
cord-347298-7kqrl3rv	524	8	implicated	implicate	VBN
cord-347298-7kqrl3rv	524	9	as	as	IN
cord-347298-7kqrl3rv	524	10	a	a	DT
cord-347298-7kqrl3rv	524	11	major	major	JJ
cord-347298-7kqrl3rv	524	12	causative	causative	JJ
cord-347298-7kqrl3rv	524	13	agent	agent	NN
cord-347298-7kqrl3rv	524	14	in	in	IN
cord-347298-7kqrl3rv	524	15	the	the	DT
cord-347298-7kqrl3rv	524	16	development	development	NN
cord-347298-7kqrl3rv	524	17	of	of	IN
cord-347298-7kqrl3rv	524	18	experimental	experimental	JJ
cord-347298-7kqrl3rv	524	19	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	524	20	orchitis	orchitis	NN
cord-347298-7kqrl3rv	524	21	(	(	-LRB-
cord-347298-7kqrl3rv	524	22	EAO	EAO	NNP
cord-347298-7kqrl3rv	524	23	)	)	-RRB-
cord-347298-7kqrl3rv	524	24	(	(	-LRB-
cord-347298-7kqrl3rv	524	25	Yule	Yule	NNP
cord-347298-7kqrl3rv	524	26	and	and	CC
cord-347298-7kqrl3rv	524	27	Tung	Tung	NNP
cord-347298-7kqrl3rv	524	28	1993	1993	CD
cord-347298-7kqrl3rv	524	29	)	)	-RRB-
cord-347298-7kqrl3rv	524	30	.	.	.
cord-347298-7kqrl3rv	525	1	There	there	EX
cord-347298-7kqrl3rv	525	2	is	be	VBZ
cord-347298-7kqrl3rv	525	3	a	a	DT
cord-347298-7kqrl3rv	525	4	significant	significant	JJ
cord-347298-7kqrl3rv	525	5	increase	increase	NN
cord-347298-7kqrl3rv	525	6	in	in	IN
cord-347298-7kqrl3rv	525	7	the	the	DT
cord-347298-7kqrl3rv	525	8	number	number	NN
cord-347298-7kqrl3rv	525	9	of	of	IN
cord-347298-7kqrl3rv	525	10	TNF	TNF	NNP
cord-347298-7kqrl3rv	525	11	-	-	HYPH
cord-347298-7kqrl3rv	525	12	positive	positive	JJ
cord-347298-7kqrl3rv	525	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	525	14	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	525	15	and	and	CC
cord-347298-7kqrl3rv	525	16	the	the	DT
cord-347298-7kqrl3rv	525	17	number	number	NN
cord-347298-7kqrl3rv	525	18	of	of	IN
cord-347298-7kqrl3rv	525	19	TNFR1-positive	TNFR1-positive	NNP
cord-347298-7kqrl3rv	525	20	germ	germ	NN
cord-347298-7kqrl3rv	525	21	cells	cell	NNS
cord-347298-7kqrl3rv	525	22	undergoing	undergo	VBG
cord-347298-7kqrl3rv	525	23	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	525	24	during	during	IN
cord-347298-7kqrl3rv	525	25	EAO	EAO	NNP
cord-347298-7kqrl3rv	525	26	in	in	IN
cord-347298-7kqrl3rv	525	27	rats	rat	NNS
cord-347298-7kqrl3rv	525	28	(	(	-LRB-
cord-347298-7kqrl3rv	525	29	Suescun	Suescun	NNP
cord-347298-7kqrl3rv	525	30	et	et	NNP
cord-347298-7kqrl3rv	525	31	al	al	NNP
cord-347298-7kqrl3rv	525	32	.	.	NNP
cord-347298-7kqrl3rv	525	33	2003	2003	CD
cord-347298-7kqrl3rv	525	34	)	)	-RRB-
cord-347298-7kqrl3rv	525	35	.	.	.
cord-347298-7kqrl3rv	526	1	Within	within	IN
cord-347298-7kqrl3rv	526	2	the	the	DT
cord-347298-7kqrl3rv	526	3	interstitium	interstitium	NN
cord-347298-7kqrl3rv	526	4	,	,	,
cord-347298-7kqrl3rv	526	5	TNF	TNF	NNP
cord-347298-7kqrl3rv	526	6	acts	act	VBZ
cord-347298-7kqrl3rv	526	7	as	as	IN
cord-347298-7kqrl3rv	526	8	an	an	DT
cord-347298-7kqrl3rv	526	9	effective	effective	JJ
cord-347298-7kqrl3rv	526	10	regulator	regulator	NN
cord-347298-7kqrl3rv	526	11	of	of	IN
cord-347298-7kqrl3rv	526	12	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	526	13	cell	cell	NN
cord-347298-7kqrl3rv	526	14	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	526	15	,	,	,
cord-347298-7kqrl3rv	526	16	by	by	IN
cord-347298-7kqrl3rv	526	17	inhibiting	inhibit	VBG
cord-347298-7kqrl3rv	526	18	LH	LH	NNP
cord-347298-7kqrl3rv	526	19	receptor	receptor	NN
cord-347298-7kqrl3rv	526	20	binding	binding	NN
cord-347298-7kqrl3rv	526	21	and	and	CC
cord-347298-7kqrl3rv	526	22	steroidogenic	steroidogenic	NNP
cord-347298-7kqrl3rv	526	23	gene	gene	NN
cord-347298-7kqrl3rv	526	24	expression	expression	NN
cord-347298-7kqrl3rv	526	25	(	(	-LRB-
cord-347298-7kqrl3rv	526	26	Li	Li	NNP
cord-347298-7kqrl3rv	526	27	et	et	NNP
cord-347298-7kqrl3rv	526	28	al	al	NNP
cord-347298-7kqrl3rv	526	29	.	.	NNP
cord-347298-7kqrl3rv	526	30	1995	1995	CD
cord-347298-7kqrl3rv	526	31	;	;	:
cord-347298-7kqrl3rv	527	1	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	527	2	et	et	NNP
cord-347298-7kqrl3rv	527	3	al	al	NNP
cord-347298-7kqrl3rv	527	4	.	.	.
cord-347298-7kqrl3rv	528	1	1991b	1991b	CD
cord-347298-7kqrl3rv	529	1	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	529	2	et	et	NNP
cord-347298-7kqrl3rv	529	3	al	al	NNP
cord-347298-7kqrl3rv	529	4	.	.	NNP
cord-347298-7kqrl3rv	529	5	,	,	,
cord-347298-7kqrl3rv	529	6	1998	1998	CD
cord-347298-7kqrl3rv	529	7	Hales	Hales	NNP
cord-347298-7kqrl3rv	529	8	1993b	1993b	CD
cord-347298-7kqrl3rv	529	9	,	,	,
cord-347298-7kqrl3rv	529	10	1994	1994	CD
cord-347298-7kqrl3rv	529	11	)	)	-RRB-
cord-347298-7kqrl3rv	529	12	.	.	.
cord-347298-7kqrl3rv	530	1	No	no	DT
cord-347298-7kqrl3rv	530	2	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	530	3	cytokine	cytokine	NN
cord-347298-7kqrl3rv	530	4	has	have	VBZ
cord-347298-7kqrl3rv	530	5	excited	excite	VBN
cord-347298-7kqrl3rv	530	6	more	more	JJR
cord-347298-7kqrl3rv	530	7	controversy	controversy	NN
cord-347298-7kqrl3rv	530	8	than	than	IN
cord-347298-7kqrl3rv	530	9	the	the	DT
cord-347298-7kqrl3rv	530	10	cell	cell	NN
cord-347298-7kqrl3rv	530	11	death	death	NN
cord-347298-7kqrl3rv	530	12	signaling	signal	VBG
cord-347298-7kqrl3rv	530	13	ligand	ligand	NN
cord-347298-7kqrl3rv	531	1	FasL.	FasL.	NNP
cord-347298-7kqrl3rv	531	2	Interactions	Interactions	NNP
cord-347298-7kqrl3rv	531	3	between	between	IN
cord-347298-7kqrl3rv	531	4	FasL	FasL	NNP
cord-347298-7kqrl3rv	531	5	and	and	CC
cord-347298-7kqrl3rv	531	6	its	-PRON-	PRP$
cord-347298-7kqrl3rv	531	7	receptor	receptor	NN
cord-347298-7kqrl3rv	531	8	on	on	IN
cord-347298-7kqrl3rv	531	9	activated	activate	VBN
cord-347298-7kqrl3rv	531	10	T	t	NN
cord-347298-7kqrl3rv	531	11	cells	cell	NNS
cord-347298-7kqrl3rv	531	12	are	be	VBP
cord-347298-7kqrl3rv	531	13	important	important	JJ
cord-347298-7kqrl3rv	531	14	in	in	IN
cord-347298-7kqrl3rv	531	15	the	the	DT
cord-347298-7kqrl3rv	531	16	regulation	regulation	NN
cord-347298-7kqrl3rv	531	17	of	of	IN
cord-347298-7kqrl3rv	531	18	the	the	DT
cord-347298-7kqrl3rv	531	19	immune	immune	JJ
cord-347298-7kqrl3rv	531	20	response	response	NN
cord-347298-7kqrl3rv	531	21	(	(	-LRB-
cord-347298-7kqrl3rv	531	22	Ju	Ju	NNP
cord-347298-7kqrl3rv	531	23	et	et	NNP
cord-347298-7kqrl3rv	531	24	al	al	NNP
cord-347298-7kqrl3rv	531	25	.	.	NNP
cord-347298-7kqrl3rv	531	26	1995	1995	CD
cord-347298-7kqrl3rv	531	27	)	)	-RRB-
cord-347298-7kqrl3rv	531	28	.	.	.
cord-347298-7kqrl3rv	532	1	The	the	DT
cord-347298-7kqrl3rv	532	2	death	death	NN
cord-347298-7kqrl3rv	532	3	domain	domain	NN
cord-347298-7kqrl3rv	532	4	in	in	IN
cord-347298-7kqrl3rv	532	5	the	the	DT
cord-347298-7kqrl3rv	532	6	cytoplasmic	cytoplasmic	JJ
cord-347298-7kqrl3rv	532	7	region	region	NN
cord-347298-7kqrl3rv	532	8	of	of	IN
cord-347298-7kqrl3rv	532	9	the	the	DT
cord-347298-7kqrl3rv	532	10	Fas	Fas	NNP
cord-347298-7kqrl3rv	532	11	receptor	receptor	NN
cord-347298-7kqrl3rv	532	12	recruits	recruit	VBZ
cord-347298-7kqrl3rv	532	13	the	the	DT
cord-347298-7kqrl3rv	532	14	FADD	FADD	NNP
cord-347298-7kqrl3rv	532	15	adaptor	adaptor	NN
cord-347298-7kqrl3rv	532	16	protein	protein	NN
cord-347298-7kqrl3rv	532	17	and	and	CC
cord-347298-7kqrl3rv	532	18	induces	induce	VBZ
cord-347298-7kqrl3rv	532	19	T	T	NNP
cord-347298-7kqrl3rv	532	20	cell	cell	NN
cord-347298-7kqrl3rv	532	21	death	death	NN
cord-347298-7kqrl3rv	532	22	via	via	IN
cord-347298-7kqrl3rv	532	23	caspase	caspase	NN
cord-347298-7kqrl3rv	532	24	-	-	HYPH
cord-347298-7kqrl3rv	532	25	dependent	dependent	JJ
cord-347298-7kqrl3rv	532	26	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	533	1	(	(	-LRB-
cord-347298-7kqrl3rv	533	2	Schütze	Schütze	NNP
cord-347298-7kqrl3rv	533	3	et	et	NNP
cord-347298-7kqrl3rv	533	4	al	al	NNP
cord-347298-7kqrl3rv	533	5	.	.	NNP
cord-347298-7kqrl3rv	533	6	2008	2008	CD
cord-347298-7kqrl3rv	533	7	)	)	-RRB-
cord-347298-7kqrl3rv	533	8	.	.	.
cord-347298-7kqrl3rv	534	1	There	there	EX
cord-347298-7kqrl3rv	534	2	is	be	VBZ
cord-347298-7kqrl3rv	534	3	evidence	evidence	NN
cord-347298-7kqrl3rv	534	4	that	that	IN
cord-347298-7kqrl3rv	534	5	FasL	FasL	NNP
cord-347298-7kqrl3rv	534	6	expression	expression	NN
cord-347298-7kqrl3rv	534	7	on	on	IN
cord-347298-7kqrl3rv	534	8	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	534	9	cells	cell	NNS
cord-347298-7kqrl3rv	534	10	in	in	IN
cord-347298-7kqrl3rv	534	11	immune	immune	NN
cord-347298-7kqrl3rv	534	12	-	-	HYPH
cord-347298-7kqrl3rv	534	13	privileged	privileged	JJ
cord-347298-7kqrl3rv	534	14	tissues	tissue	NNS
cord-347298-7kqrl3rv	534	15	,	,	,
cord-347298-7kqrl3rv	534	16	including	include	VBG
cord-347298-7kqrl3rv	534	17	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	534	18	cells	cell	NNS
cord-347298-7kqrl3rv	534	19	,	,	,
cord-347298-7kqrl3rv	534	20	may	may	MD
cord-347298-7kqrl3rv	534	21	be	be	VB
cord-347298-7kqrl3rv	534	22	responsible	responsible	JJ
cord-347298-7kqrl3rv	534	23	for	for	IN
cord-347298-7kqrl3rv	534	24	deleting	delete	VBG
cord-347298-7kqrl3rv	534	25	activated	activate	VBN
cord-347298-7kqrl3rv	534	26	T	T	NNP
cord-347298-7kqrl3rv	534	27	cells	cell	NNS
cord-347298-7kqrl3rv	534	28	within	within	IN
cord-347298-7kqrl3rv	534	29	the	the	DT
cord-347298-7kqrl3rv	534	30	tissue	tissue	NN
cord-347298-7kqrl3rv	534	31	,	,	,
cord-347298-7kqrl3rv	534	32	thereby	thereby	RB
cord-347298-7kqrl3rv	534	33	suppressing	suppress	VBG
cord-347298-7kqrl3rv	534	34	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	534	35	immunity	immunity	NN
cord-347298-7kqrl3rv	534	36	(	(	-LRB-
cord-347298-7kqrl3rv	534	37	Bellgrau	Bellgrau	NNP
cord-347298-7kqrl3rv	534	38	et	et	NNP
cord-347298-7kqrl3rv	534	39	al	al	NNP
cord-347298-7kqrl3rv	534	40	.	.	NNP
cord-347298-7kqrl3rv	534	41	1995	1995	CD
cord-347298-7kqrl3rv	534	42	;	;	:
cord-347298-7kqrl3rv	534	43	Griffith	Griffith	NNP
cord-347298-7kqrl3rv	534	44	et	et	NNP
cord-347298-7kqrl3rv	534	45	al	al	NNP
cord-347298-7kqrl3rv	534	46	.	.	.
cord-347298-7kqrl3rv	534	47	1996	1996	CD
cord-347298-7kqrl3rv	534	48	;	;	:
cord-347298-7kqrl3rv	534	49	Saas	Saas	NNP
cord-347298-7kqrl3rv	534	50	et	et	NNP
cord-347298-7kqrl3rv	534	51	al	al	NNP
cord-347298-7kqrl3rv	534	52	.	.	.
cord-347298-7kqrl3rv	535	1	1997	1997	CD
cord-347298-7kqrl3rv	535	2	;	;	:
cord-347298-7kqrl3rv	535	3	Stuart	Stuart	NNP
cord-347298-7kqrl3rv	535	4	et	et	NNP
cord-347298-7kqrl3rv	535	5	al	al	NNP
cord-347298-7kqrl3rv	535	6	.	.	.
cord-347298-7kqrl3rv	535	7	1997	1997	CD
cord-347298-7kqrl3rv	535	8	)	)	-RRB-
cord-347298-7kqrl3rv	535	9	.	.	.
cord-347298-7kqrl3rv	536	1	However	however	RB
cord-347298-7kqrl3rv	536	2	,	,	,
cord-347298-7kqrl3rv	536	3	this	this	DT
cord-347298-7kqrl3rv	536	4	hypothesis	hypothesis	NN
cord-347298-7kqrl3rv	536	5	has	have	VBZ
cord-347298-7kqrl3rv	536	6	been	be	VBN
cord-347298-7kqrl3rv	536	7	challenged	challenge	VBN
cord-347298-7kqrl3rv	536	8	by	by	IN
cord-347298-7kqrl3rv	536	9	the	the	DT
cord-347298-7kqrl3rv	536	10	observation	observation	NN
cord-347298-7kqrl3rv	536	11	that	that	WDT
cord-347298-7kqrl3rv	536	12	increased	increase	VBD
cord-347298-7kqrl3rv	536	13	FasL	FasL	NNP
cord-347298-7kqrl3rv	536	14	expression	expression	NN
cord-347298-7kqrl3rv	536	15	on	on	IN
cord-347298-7kqrl3rv	536	16	cells	cell	NNS
cord-347298-7kqrl3rv	536	17	such	such	JJ
cord-347298-7kqrl3rv	536	18	as	as	IN
cord-347298-7kqrl3rv	536	19	tumor	tumor	NN
cord-347298-7kqrl3rv	536	20	cell	cell	NN
cord-347298-7kqrl3rv	536	21	lines	line	NNS
cord-347298-7kqrl3rv	536	22	and	and	CC
cord-347298-7kqrl3rv	536	23	pancreatic	pancreatic	JJ
cord-347298-7kqrl3rv	536	24	islet	islet	NN
cord-347298-7kqrl3rv	536	25	cells	cell	NNS
cord-347298-7kqrl3rv	536	26	does	do	VBZ
cord-347298-7kqrl3rv	536	27	not	not	RB
cord-347298-7kqrl3rv	536	28	increase	increase	VB
cord-347298-7kqrl3rv	536	29	protection	protection	NN
cord-347298-7kqrl3rv	536	30	in	in	IN
cord-347298-7kqrl3rv	536	31	transplantation	transplantation	NN
cord-347298-7kqrl3rv	536	32	studies	study	NNS
cord-347298-7kqrl3rv	536	33	,	,	,
cord-347298-7kqrl3rv	536	34	but	but	CC
cord-347298-7kqrl3rv	536	35	actually	actually	RB
cord-347298-7kqrl3rv	536	36	provokes	provoke	VBZ
cord-347298-7kqrl3rv	536	37	a	a	DT
cord-347298-7kqrl3rv	536	38	massive	massive	JJ
cord-347298-7kqrl3rv	536	39	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	536	40	reaction	reaction	NN
cord-347298-7kqrl3rv	536	41	and	and	CC
cord-347298-7kqrl3rv	536	42	rejection	rejection	NN
cord-347298-7kqrl3rv	536	43	(	(	-LRB-
cord-347298-7kqrl3rv	536	44	Allison	Allison	NNP
cord-347298-7kqrl3rv	536	45	et	et	NNP
cord-347298-7kqrl3rv	536	46	al	al	NNP
cord-347298-7kqrl3rv	536	47	.	.	.
cord-347298-7kqrl3rv	536	48	1997	1997	CD
cord-347298-7kqrl3rv	536	49	;	;	:
cord-347298-7kqrl3rv	536	50	Kang	Kang	NNP
cord-347298-7kqrl3rv	536	51	et	et	NNP
cord-347298-7kqrl3rv	536	52	al	al	NNP
cord-347298-7kqrl3rv	536	53	.	.	.
cord-347298-7kqrl3rv	536	54	1997	1997	CD
cord-347298-7kqrl3rv	536	55	)	)	-RRB-
cord-347298-7kqrl3rv	536	56	.	.	.
cord-347298-7kqrl3rv	537	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	537	2	,	,	,
cord-347298-7kqrl3rv	537	3	FasL	FasL	NNP
cord-347298-7kqrl3rv	537	4	appears	appear	VBZ
cord-347298-7kqrl3rv	537	5	to	to	TO
cord-347298-7kqrl3rv	537	6	be	be	VB
cord-347298-7kqrl3rv	537	7	abundantly	abundantly	RB
cord-347298-7kqrl3rv	537	8	expressed	express	VBN
cord-347298-7kqrl3rv	537	9	in	in	IN
cord-347298-7kqrl3rv	537	10	the	the	DT
cord-347298-7kqrl3rv	537	11	epithelia	epithelium	NNS
cord-347298-7kqrl3rv	537	12	of	of	IN
cord-347298-7kqrl3rv	537	13	several	several	JJ
cord-347298-7kqrl3rv	537	14	human	human	JJ
cord-347298-7kqrl3rv	537	15	tissues	tissue	NNS
cord-347298-7kqrl3rv	537	16	that	that	WDT
cord-347298-7kqrl3rv	537	17	lack	lack	VBP
cord-347298-7kqrl3rv	537	18	any	any	DT
cord-347298-7kqrl3rv	537	19	evidence	evidence	NN
cord-347298-7kqrl3rv	537	20	for	for	IN
cord-347298-7kqrl3rv	537	21	immunological	immunological	JJ
cord-347298-7kqrl3rv	537	22	privilege	privilege	NN
cord-347298-7kqrl3rv	537	23	(	(	-LRB-
cord-347298-7kqrl3rv	537	24	Xerri	Xerri	NNP
cord-347298-7kqrl3rv	537	25	et	et	NNP
cord-347298-7kqrl3rv	537	26	al	al	NNP
cord-347298-7kqrl3rv	537	27	.	.	.
cord-347298-7kqrl3rv	537	28	1997	1997	CD
cord-347298-7kqrl3rv	537	29	)	)	-RRB-
cord-347298-7kqrl3rv	537	30	,	,	,
cord-347298-7kqrl3rv	537	31	while	while	IN
cord-347298-7kqrl3rv	537	32	absence	absence	NN
cord-347298-7kqrl3rv	537	33	or	or	CC
cord-347298-7kqrl3rv	537	34	inhibition	inhibition	NN
cord-347298-7kqrl3rv	537	35	of	of	IN
cord-347298-7kqrl3rv	537	36	Fas	Fas	NNP
cord-347298-7kqrl3rv	537	37	or	or	CC
cord-347298-7kqrl3rv	537	38	FasL	FasL	NNP
cord-347298-7kqrl3rv	537	39	does	do	VBZ
cord-347298-7kqrl3rv	537	40	not	not	RB
cord-347298-7kqrl3rv	537	41	automatically	automatically	RB
cord-347298-7kqrl3rv	537	42	cause	cause	VB
cord-347298-7kqrl3rv	537	43	failure	failure	NN
cord-347298-7kqrl3rv	537	44	of	of	IN
cord-347298-7kqrl3rv	537	45	immune	immune	JJ
cord-347298-7kqrl3rv	537	46	privilege	privilege	NN
cord-347298-7kqrl3rv	537	47	(	(	-LRB-
cord-347298-7kqrl3rv	537	48	Rogers	Rogers	NNP
cord-347298-7kqrl3rv	537	49	et	et	NNP
cord-347298-7kqrl3rv	537	50	al	al	NNP
cord-347298-7kqrl3rv	537	51	.	.	.
cord-347298-7kqrl3rv	538	1	1998	1998	CD
cord-347298-7kqrl3rv	538	2	;	;	:
cord-347298-7kqrl3rv	538	3	Suarez	Suarez	NNP
cord-347298-7kqrl3rv	538	4	-	-	HYPH
cord-347298-7kqrl3rv	538	5	Pinzon	Pinzon	NNP
cord-347298-7kqrl3rv	538	6	et	et	NNP
cord-347298-7kqrl3rv	538	7	al	al	NNP
cord-347298-7kqrl3rv	538	8	.	.	.
cord-347298-7kqrl3rv	539	1	2000	2000	CD
cord-347298-7kqrl3rv	539	2	;	;	:
cord-347298-7kqrl3rv	539	3	Wahlsten	Wahlsten	NNP
cord-347298-7kqrl3rv	539	4	et	et	NNP
cord-347298-7kqrl3rv	539	5	al	al	NNP
cord-347298-7kqrl3rv	539	6	.	.	.
cord-347298-7kqrl3rv	539	7	2000	2000	CD
cord-347298-7kqrl3rv	539	8	)	)	-RRB-
cord-347298-7kqrl3rv	539	9	.	.	.
cord-347298-7kqrl3rv	540	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	540	2	seems	seem	VBZ
cord-347298-7kqrl3rv	540	3	unlikely	unlikely	JJ
cord-347298-7kqrl3rv	540	4	that	that	IN
cord-347298-7kqrl3rv	540	5	FasL	FasL	NNP
cord-347298-7kqrl3rv	540	6	expression	expression	NN
cord-347298-7kqrl3rv	540	7	on	on	IN
cord-347298-7kqrl3rv	540	8	its	-PRON-	PRP$
cord-347298-7kqrl3rv	540	9	own	own	JJ
cord-347298-7kqrl3rv	540	10	is	be	VBZ
cord-347298-7kqrl3rv	540	11	a	a	DT
cord-347298-7kqrl3rv	540	12	fundamental	fundamental	JJ
cord-347298-7kqrl3rv	540	13	explanation	explanation	NN
cord-347298-7kqrl3rv	540	14	for	for	IN
cord-347298-7kqrl3rv	540	15	immune	immune	JJ
cord-347298-7kqrl3rv	540	16	privilege	privilege	NN
cord-347298-7kqrl3rv	540	17	,	,	,
cord-347298-7kqrl3rv	540	18	although	although	IN
cord-347298-7kqrl3rv	540	19	it	-PRON-	PRP
cord-347298-7kqrl3rv	540	20	may	may	MD
cord-347298-7kqrl3rv	540	21	contribute	contribute	VB
cord-347298-7kqrl3rv	540	22	through	through	IN
cord-347298-7kqrl3rv	540	23	interaction	interaction	NN
cord-347298-7kqrl3rv	540	24	with	with	IN
cord-347298-7kqrl3rv	540	25	other	other	JJ
cord-347298-7kqrl3rv	540	26	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	540	27	processes	process	NNS
cord-347298-7kqrl3rv	540	28	.	.	.
cord-347298-7kqrl3rv	541	1	Localization	localization	NN
cord-347298-7kqrl3rv	541	2	of	of	IN
cord-347298-7kqrl3rv	541	3	FasL	FasL	NNP
cord-347298-7kqrl3rv	541	4	and	and	CC
cord-347298-7kqrl3rv	541	5	Fas	Fas	NNP
cord-347298-7kqrl3rv	541	6	in	in	IN
cord-347298-7kqrl3rv	541	7	the	the	DT
cord-347298-7kqrl3rv	541	8	testis	testis	NN
cord-347298-7kqrl3rv	541	9	under	under	IN
cord-347298-7kqrl3rv	541	10	normal	normal	JJ
cord-347298-7kqrl3rv	541	11	conditions	condition	NNS
cord-347298-7kqrl3rv	541	12	also	also	RB
cord-347298-7kqrl3rv	541	13	has	have	VBZ
cord-347298-7kqrl3rv	541	14	proven	prove	VBN
cord-347298-7kqrl3rv	541	15	controversial	controversial	JJ
cord-347298-7kqrl3rv	541	16	,	,	,
cord-347298-7kqrl3rv	541	17	which	which	WDT
cord-347298-7kqrl3rv	541	18	may	may	MD
cord-347298-7kqrl3rv	541	19	be	be	VB
cord-347298-7kqrl3rv	541	20	attributed	attribute	VBN
cord-347298-7kqrl3rv	541	21	to	to	IN
cord-347298-7kqrl3rv	541	22	differences	difference	NNS
cord-347298-7kqrl3rv	541	23	in	in	IN
cord-347298-7kqrl3rv	541	24	detection	detection	NN
cord-347298-7kqrl3rv	541	25	methods	method	NNS
cord-347298-7kqrl3rv	541	26	,	,	,
cord-347298-7kqrl3rv	541	27	limitations	limitation	NNS
cord-347298-7kqrl3rv	541	28	of	of	IN
cord-347298-7kqrl3rv	541	29	some	some	DT
cord-347298-7kqrl3rv	541	30	of	of	IN
cord-347298-7kqrl3rv	541	31	the	the	DT
cord-347298-7kqrl3rv	541	32	reagents	reagent	NNS
cord-347298-7kqrl3rv	541	33	that	that	WDT
cord-347298-7kqrl3rv	541	34	have	have	VBP
cord-347298-7kqrl3rv	541	35	been	be	VBN
cord-347298-7kqrl3rv	541	36	used	use	VBN
cord-347298-7kqrl3rv	541	37	,	,	,
cord-347298-7kqrl3rv	541	38	and	and	CC
cord-347298-7kqrl3rv	541	39	the	the	DT
cord-347298-7kqrl3rv	541	40	fact	fact	NN
cord-347298-7kqrl3rv	541	41	that	that	IN
cord-347298-7kqrl3rv	541	42	these	these	DT
cord-347298-7kqrl3rv	541	43	molecules	molecule	NNS
cord-347298-7kqrl3rv	541	44	are	be	VBP
cord-347298-7kqrl3rv	541	45	inducible	inducible	JJ
cord-347298-7kqrl3rv	541	46	(	(	-LRB-
cord-347298-7kqrl3rv	541	47	D'Alessio	D'Alessio	NNP
cord-347298-7kqrl3rv	541	48	et	et	FW
cord-347298-7kqrl3rv	541	49	al	al	NNP
cord-347298-7kqrl3rv	541	50	.	.	NNP
cord-347298-7kqrl3rv	541	51	2001	2001	CD
cord-347298-7kqrl3rv	541	52	;	;	:
cord-347298-7kqrl3rv	541	53	Restifo	Restifo	NNP
cord-347298-7kqrl3rv	541	54	2000	2000	CD
cord-347298-7kqrl3rv	541	55	)	)	-RRB-
cord-347298-7kqrl3rv	541	56	.	.	.
cord-347298-7kqrl3rv	542	1	Studies	study	NNS
cord-347298-7kqrl3rv	542	2	have	have	VBP
cord-347298-7kqrl3rv	542	3	shown	show	VBN
cord-347298-7kqrl3rv	542	4	FasL	FasL	NNP
cord-347298-7kqrl3rv	542	5	to	to	TO
cord-347298-7kqrl3rv	542	6	be	be	VB
cord-347298-7kqrl3rv	542	7	present	present	JJ
cord-347298-7kqrl3rv	542	8	in	in	IN
cord-347298-7kqrl3rv	542	9	rat	rat	NN
cord-347298-7kqrl3rv	542	10	,	,	,
cord-347298-7kqrl3rv	542	11	mouse	mouse	NN
cord-347298-7kqrl3rv	542	12	,	,	,
cord-347298-7kqrl3rv	542	13	porcine	porcine	JJ
cord-347298-7kqrl3rv	542	14	,	,	,
cord-347298-7kqrl3rv	542	15	and	and	CC
cord-347298-7kqrl3rv	542	16	human	human	JJ
cord-347298-7kqrl3rv	542	17	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	542	18	cells	cell	NNS
cord-347298-7kqrl3rv	542	19	and	and	CC
cord-347298-7kqrl3rv	542	20	absent	absent	JJ
cord-347298-7kqrl3rv	542	21	in	in	IN
cord-347298-7kqrl3rv	542	22	most	most	JJS
cord-347298-7kqrl3rv	542	23	germ	germ	NN
cord-347298-7kqrl3rv	542	24	cells	cell	NNS
cord-347298-7kqrl3rv	543	1	(	(	-LRB-
cord-347298-7kqrl3rv	543	2	Bellgrau	Bellgrau	NNP
cord-347298-7kqrl3rv	543	3	et	et	NNP
cord-347298-7kqrl3rv	543	4	al	al	NNP
cord-347298-7kqrl3rv	543	5	.	.	.
cord-347298-7kqrl3rv	544	1	1995	1995	CD
cord-347298-7kqrl3rv	544	2	;	;	:
cord-347298-7kqrl3rv	544	3	Braendstrup	Braendstrup	NNP
cord-347298-7kqrl3rv	544	4	et	et	NNP
cord-347298-7kqrl3rv	544	5	al	al	NNP
cord-347298-7kqrl3rv	544	6	.	.	.
cord-347298-7kqrl3rv	545	1	1999	1999	CD
cord-347298-7kqrl3rv	545	2	;	;	:
cord-347298-7kqrl3rv	545	3	D'Abrizio	D'Abrizio	NNP
cord-347298-7kqrl3rv	545	4	et	et	FW
cord-347298-7kqrl3rv	545	5	al	al	NNP
cord-347298-7kqrl3rv	545	6	.	.	.
cord-347298-7kqrl3rv	546	1	2004	2004	CD
cord-347298-7kqrl3rv	546	2	;	;	:
cord-347298-7kqrl3rv	546	3	Lee	Lee	NNP
cord-347298-7kqrl3rv	546	4	et	et	NNP
cord-347298-7kqrl3rv	546	5	al	al	NNP
cord-347298-7kqrl3rv	546	6	.	.	.
cord-347298-7kqrl3rv	546	7	1997	1997	CD
cord-347298-7kqrl3rv	546	8	)	)	-RRB-
cord-347298-7kqrl3rv	546	9	,	,	,
cord-347298-7kqrl3rv	546	10	but	but	CC
cord-347298-7kqrl3rv	546	11	other	other	JJ
cord-347298-7kqrl3rv	546	12	studies	study	NNS
cord-347298-7kqrl3rv	546	13	have	have	VBP
cord-347298-7kqrl3rv	546	14	reported	report	VBN
cord-347298-7kqrl3rv	546	15	that	that	IN
cord-347298-7kqrl3rv	546	16	FasL	FasL	NNP
cord-347298-7kqrl3rv	546	17	expression	expression	NN
cord-347298-7kqrl3rv	546	18	in	in	IN
cord-347298-7kqrl3rv	546	19	the	the	DT
cord-347298-7kqrl3rv	546	20	rat	rat	NN
cord-347298-7kqrl3rv	546	21	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	546	22	epithelium	epithelium	NN
cord-347298-7kqrl3rv	546	23	is	be	VBZ
cord-347298-7kqrl3rv	546	24	confined	confine	VBN
cord-347298-7kqrl3rv	546	25	to	to	IN
cord-347298-7kqrl3rv	546	26	the	the	DT
cord-347298-7kqrl3rv	546	27	germ	germ	NN
cord-347298-7kqrl3rv	546	28	cells	cell	NNS
cord-347298-7kqrl3rv	546	29	(	(	-LRB-
cord-347298-7kqrl3rv	546	30	Celik	Celik	NNP
cord-347298-7kqrl3rv	546	31	-	-	HYPH
cord-347298-7kqrl3rv	546	32	Ozenci	Ozenci	NNP
cord-347298-7kqrl3rv	546	33	et	et	FW
cord-347298-7kqrl3rv	546	34	al	al	NNP
cord-347298-7kqrl3rv	546	35	.	.	.
cord-347298-7kqrl3rv	546	36	2006	2006	CD
cord-347298-7kqrl3rv	546	37	;	;	.
cord-347298-7kqrl3rv	547	1	D'Alessio	D'Alessio	NNP
cord-347298-7kqrl3rv	547	2	et	et	NNP
cord-347298-7kqrl3rv	547	3	al	al	NNP
cord-347298-7kqrl3rv	547	4	.	.	NNP
cord-347298-7kqrl3rv	547	5	2001	2001	CD
cord-347298-7kqrl3rv	547	6	)	)	-RRB-
cord-347298-7kqrl3rv	547	7	.	.	.
cord-347298-7kqrl3rv	548	1	The	the	DT
cord-347298-7kqrl3rv	548	2	receptor	receptor	NN
cord-347298-7kqrl3rv	548	3	Fas	Fas	NNP
cord-347298-7kqrl3rv	548	4	has	have	VBZ
cord-347298-7kqrl3rv	548	5	been	be	VBN
cord-347298-7kqrl3rv	548	6	found	find	VBN
cord-347298-7kqrl3rv	548	7	on	on	IN
cord-347298-7kqrl3rv	548	8	isolated	isolate	VBN
cord-347298-7kqrl3rv	548	9	mouse	mouse	NN
cord-347298-7kqrl3rv	548	10	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	548	11	cells	cell	NNS
cord-347298-7kqrl3rv	548	12	(	(	-LRB-
cord-347298-7kqrl3rv	548	13	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	548	14	et	et	NNP
cord-347298-7kqrl3rv	548	15	al	al	NNP
cord-347298-7kqrl3rv	548	16	.	.	.
cord-347298-7kqrl3rv	548	17	2000	2000	CD
cord-347298-7kqrl3rv	548	18	)	)	-RRB-
cord-347298-7kqrl3rv	548	19	,	,	,
cord-347298-7kqrl3rv	548	20	but	but	CC
cord-347298-7kqrl3rv	548	21	in	in	IN
cord-347298-7kqrl3rv	548	22	intact	intact	JJ
cord-347298-7kqrl3rv	548	23	testes	testis	NNS
cord-347298-7kqrl3rv	548	24	has	have	VBZ
cord-347298-7kqrl3rv	548	25	been	be	VBN
cord-347298-7kqrl3rv	548	26	localized	localize	VBN
cord-347298-7kqrl3rv	548	27	to	to	IN
cord-347298-7kqrl3rv	548	28	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	548	29	and	and	CC
cord-347298-7kqrl3rv	548	30	spermatocytes	spermatocytes	NNPS
cord-347298-7kqrl3rv	548	31	from	from	IN
cord-347298-7kqrl3rv	548	32	the	the	DT
cord-347298-7kqrl3rv	548	33	pubertal	pubertal	JJ
cord-347298-7kqrl3rv	548	34	period	period	NN
cord-347298-7kqrl3rv	548	35	onward	onward	RB
cord-347298-7kqrl3rv	549	1	(	(	-LRB-
cord-347298-7kqrl3rv	549	2	Celik	Celik	NNP
cord-347298-7kqrl3rv	549	3	-	-	HYPH
cord-347298-7kqrl3rv	549	4	Ozenci	Ozenci	NNP
cord-347298-7kqrl3rv	549	5	et	et	FW
cord-347298-7kqrl3rv	549	6	al	al	NNP
cord-347298-7kqrl3rv	549	7	.	.	.
cord-347298-7kqrl3rv	550	1	2006	2006	CD
cord-347298-7kqrl3rv	551	1	;	;	:
cord-347298-7kqrl3rv	551	2	Lee	Lee	NNP
cord-347298-7kqrl3rv	551	3	et	et	NNP
cord-347298-7kqrl3rv	551	4	al	al	NNP
cord-347298-7kqrl3rv	551	5	.	.	.
cord-347298-7kqrl3rv	552	1	1997	1997	CD
cord-347298-7kqrl3rv	552	2	;	;	:
cord-347298-7kqrl3rv	552	3	Lizama	Lizama	NNP
cord-347298-7kqrl3rv	552	4	et	et	NNP
cord-347298-7kqrl3rv	552	5	al	al	NNP
cord-347298-7kqrl3rv	552	6	.	.	.
cord-347298-7kqrl3rv	553	1	2007	2007	CD
cord-347298-7kqrl3rv	553	2	;	;	:
cord-347298-7kqrl3rv	553	3	Ogi	Ogi	NNP
cord-347298-7kqrl3rv	553	4	et	et	NNP
cord-347298-7kqrl3rv	553	5	al	al	NNP
cord-347298-7kqrl3rv	553	6	.	.	NNP
cord-347298-7kqrl3rv	553	7	1998	1998	CD
cord-347298-7kqrl3rv	553	8	)	)	-RRB-
cord-347298-7kqrl3rv	553	9	.	.	.
cord-347298-7kqrl3rv	554	1	In	in	IN
cord-347298-7kqrl3rv	554	2	germ	germ	NN
cord-347298-7kqrl3rv	554	3	cells	cell	NNS
cord-347298-7kqrl3rv	554	4	,	,	,
cord-347298-7kqrl3rv	554	5	Fas	Fas	NNP
cord-347298-7kqrl3rv	554	6	expression	expression	NN
cord-347298-7kqrl3rv	554	7	is	be	VBZ
cord-347298-7kqrl3rv	554	8	associated	associate	VBN
cord-347298-7kqrl3rv	554	9	with	with	IN
cord-347298-7kqrl3rv	554	10	cells	cell	NNS
cord-347298-7kqrl3rv	554	11	that	that	WDT
cord-347298-7kqrl3rv	554	12	are	be	VBP
cord-347298-7kqrl3rv	554	13	undergoing	undergo	VBG
cord-347298-7kqrl3rv	554	14	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	554	15	(	(	-LRB-
cord-347298-7kqrl3rv	554	16	Lee	Lee	NNP
cord-347298-7kqrl3rv	554	17	et	et	NNP
cord-347298-7kqrl3rv	554	18	al	al	NNP
cord-347298-7kqrl3rv	554	19	.	.	.
cord-347298-7kqrl3rv	554	20	1997	1997	CD
cord-347298-7kqrl3rv	554	21	;	;	:
cord-347298-7kqrl3rv	554	22	Lizama	Lizama	NNP
cord-347298-7kqrl3rv	554	23	et	et	NNP
cord-347298-7kqrl3rv	554	24	al	al	NNP
cord-347298-7kqrl3rv	554	25	.	.	NNP
cord-347298-7kqrl3rv	554	26	2007	2007	CD
cord-347298-7kqrl3rv	554	27	)	)	-RRB-
cord-347298-7kqrl3rv	554	28	,	,	,
cord-347298-7kqrl3rv	554	29	and	and	CC
cord-347298-7kqrl3rv	555	1	Fas	Fas	NNP
cord-347298-7kqrl3rv	555	2	is	be	VBZ
cord-347298-7kqrl3rv	555	3	induced	induce	VBN
cord-347298-7kqrl3rv	555	4	by	by	IN
cord-347298-7kqrl3rv	555	5	TNF	TNF	NNP
cord-347298-7kqrl3rv	555	6	and	and	CC
cord-347298-7kqrl3rv	555	7	IFN	IFN	NNP
cord-347298-7kqrl3rv	555	8	in	in	IN
cord-347298-7kqrl3rv	555	9	the	the	DT
cord-347298-7kqrl3rv	555	10	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	555	11	cell	cell	NN
cord-347298-7kqrl3rv	555	12	(	(	-LRB-
cord-347298-7kqrl3rv	555	13	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	555	14	et	et	NNP
cord-347298-7kqrl3rv	555	15	al	al	NNP
cord-347298-7kqrl3rv	555	16	.	.	.
cord-347298-7kqrl3rv	555	17	2000	2000	CD
cord-347298-7kqrl3rv	555	18	)	)	-RRB-
cord-347298-7kqrl3rv	555	19	.	.	.
cord-347298-7kqrl3rv	556	1	Curiously	curiously	RB
cord-347298-7kqrl3rv	556	2	,	,	,
cord-347298-7kqrl3rv	556	3	in	in	IN
cord-347298-7kqrl3rv	556	4	one	one	CD
cord-347298-7kqrl3rv	556	5	study	study	NN
cord-347298-7kqrl3rv	556	6	using	use	VBG
cord-347298-7kqrl3rv	556	7	fragment	fragment	NN
cord-347298-7kqrl3rv	556	8	cultures	culture	NNS
cord-347298-7kqrl3rv	556	9	of	of	IN
cord-347298-7kqrl3rv	556	10	human	human	JJ
cord-347298-7kqrl3rv	556	11	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	556	12	tubules	tubule	NNS
cord-347298-7kqrl3rv	556	13	,	,	,
cord-347298-7kqrl3rv	556	14	TNF	TNF	NNP
cord-347298-7kqrl3rv	556	15	downregulated	downregulate	VBD
cord-347298-7kqrl3rv	556	16	FasL	FasL	NNP
cord-347298-7kqrl3rv	556	17	expression	expression	NN
cord-347298-7kqrl3rv	556	18	and	and	CC
cord-347298-7kqrl3rv	556	19	inhibited	inhibited	JJ
cord-347298-7kqrl3rv	556	20	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	556	21	of	of	IN
cord-347298-7kqrl3rv	556	22	germ	germ	NN
cord-347298-7kqrl3rv	556	23	cells	cell	NNS
cord-347298-7kqrl3rv	556	24	(	(	-LRB-
cord-347298-7kqrl3rv	556	25	Pentikäinen	Pentikäinen	NNP
cord-347298-7kqrl3rv	556	26	et	et	FW
cord-347298-7kqrl3rv	556	27	al	al	NNP
cord-347298-7kqrl3rv	556	28	.	.	NNP
cord-347298-7kqrl3rv	556	29	2001	2001	CD
cord-347298-7kqrl3rv	556	30	)	)	-RRB-
cord-347298-7kqrl3rv	556	31	.	.	.
cord-347298-7kqrl3rv	557	1	Less	less	RBR
cord-347298-7kqrl3rv	557	2	controversially	controversially	RB
cord-347298-7kqrl3rv	557	3	,	,	,
cord-347298-7kqrl3rv	557	4	Fas	Fas	NNP
cord-347298-7kqrl3rv	557	5	and	and	CC
cord-347298-7kqrl3rv	557	6	FasL	FasL	NNP
cord-347298-7kqrl3rv	557	7	expression	expression	NN
cord-347298-7kqrl3rv	557	8	is	be	VBZ
cord-347298-7kqrl3rv	557	9	upregulated	upregulate	VBN
cord-347298-7kqrl3rv	557	10	in	in	IN
cord-347298-7kqrl3rv	557	11	various	various	JJ
cord-347298-7kqrl3rv	557	12	models	model	NNS
cord-347298-7kqrl3rv	557	13	of	of	IN
cord-347298-7kqrl3rv	557	14	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	557	15	epithelium	epithelium	NN
cord-347298-7kqrl3rv	557	16	damage	damage	NN
cord-347298-7kqrl3rv	557	17	,	,	,
cord-347298-7kqrl3rv	557	18	indicating	indicate	VBG
cord-347298-7kqrl3rv	557	19	that	that	IN
cord-347298-7kqrl3rv	557	20	this	this	DT
cord-347298-7kqrl3rv	557	21	mechanism	mechanism	NN
cord-347298-7kqrl3rv	557	22	is	be	VBZ
cord-347298-7kqrl3rv	557	23	important	important	JJ
cord-347298-7kqrl3rv	557	24	in	in	IN
cord-347298-7kqrl3rv	557	25	regulating	regulate	VBG
cord-347298-7kqrl3rv	557	26	germ	germ	NN
cord-347298-7kqrl3rv	557	27	cell	cell	NN
cord-347298-7kqrl3rv	557	28	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	557	29	in	in	IN
cord-347298-7kqrl3rv	557	30	cases	case	NNS
cord-347298-7kqrl3rv	557	31	of	of	IN
cord-347298-7kqrl3rv	557	32	physical	physical	JJ
cord-347298-7kqrl3rv	557	33	and	and	CC
cord-347298-7kqrl3rv	557	34	toxicological	toxicological	JJ
cord-347298-7kqrl3rv	557	35	insult	insult	NN
cord-347298-7kqrl3rv	557	36	(	(	-LRB-
cord-347298-7kqrl3rv	557	37	Lee	Lee	NNP
cord-347298-7kqrl3rv	557	38	et	et	NNP
cord-347298-7kqrl3rv	557	39	al	al	NNP
cord-347298-7kqrl3rv	557	40	.	.	.
cord-347298-7kqrl3rv	557	41	1997	1997	CD
cord-347298-7kqrl3rv	557	42	;	;	.
cord-347298-7kqrl3rv	558	1	Ogi	Ogi	NNP
cord-347298-7kqrl3rv	558	2	et	et	NNP
cord-347298-7kqrl3rv	558	3	al	al	NNP
cord-347298-7kqrl3rv	558	4	.	.	NNP
cord-347298-7kqrl3rv	558	5	1998	1998	CD
cord-347298-7kqrl3rv	558	6	)	)	-RRB-
cord-347298-7kqrl3rv	558	7	.	.	.
cord-347298-7kqrl3rv	559	1	Members	member	NNS
cord-347298-7kqrl3rv	559	2	of	of	IN
cord-347298-7kqrl3rv	559	3	the	the	DT
cord-347298-7kqrl3rv	559	4	IL6	IL6	NNP
cord-347298-7kqrl3rv	559	5	family	family	NN
cord-347298-7kqrl3rv	559	6	of	of	IN
cord-347298-7kqrl3rv	559	7	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	559	8	exert	exert	VBP
cord-347298-7kqrl3rv	559	9	their	-PRON-	PRP$
cord-347298-7kqrl3rv	559	10	actions	action	NNS
cord-347298-7kqrl3rv	559	11	via	via	IN
cord-347298-7kqrl3rv	559	12	binding	bind	VBG
cord-347298-7kqrl3rv	559	13	to	to	IN
cord-347298-7kqrl3rv	559	14	specific	specific	JJ
cord-347298-7kqrl3rv	559	15	receptors	receptor	NNS
cord-347298-7kqrl3rv	559	16	that	that	WDT
cord-347298-7kqrl3rv	559	17	associate	associate	VBP
cord-347298-7kqrl3rv	559	18	with	with	IN
cord-347298-7kqrl3rv	559	19	a	a	DT
cord-347298-7kqrl3rv	559	20	common	common	JJ
cord-347298-7kqrl3rv	559	21	membrane	membrane	NN
cord-347298-7kqrl3rv	559	22	signal	signal	NN
cord-347298-7kqrl3rv	559	23	transducer	transducer	NN
cord-347298-7kqrl3rv	559	24	gp130	gp130	VBZ
cord-347298-7kqrl3rv	559	25	,	,	,
cord-347298-7kqrl3rv	559	26	leading	lead	VBG
cord-347298-7kqrl3rv	559	27	to	to	IN
cord-347298-7kqrl3rv	559	28	the	the	DT
cord-347298-7kqrl3rv	559	29	activation	activation	NN
cord-347298-7kqrl3rv	559	30	of	of	IN
cord-347298-7kqrl3rv	559	31	the	the	DT
cord-347298-7kqrl3rv	559	32	Janus	Janus	NNP
cord-347298-7kqrl3rv	559	33	kinase	kinase	NN
cord-347298-7kqrl3rv	559	34	/	/	SYM
cord-347298-7kqrl3rv	559	35	signal	signal	NN
cord-347298-7kqrl3rv	559	36	transducers	transducer	NNS
cord-347298-7kqrl3rv	559	37	and	and	CC
cord-347298-7kqrl3rv	559	38	activators	activator	NNS
cord-347298-7kqrl3rv	559	39	of	of	IN
cord-347298-7kqrl3rv	559	40	transcription	transcription	NN
cord-347298-7kqrl3rv	559	41	(	(	-LRB-
cord-347298-7kqrl3rv	559	42	Jak	Jak	NNP
cord-347298-7kqrl3rv	559	43	/	/	SYM
cord-347298-7kqrl3rv	559	44	Stat	Stat	NNP
cord-347298-7kqrl3rv	559	45	)	)	-RRB-
cord-347298-7kqrl3rv	559	46	and	and	CC
cord-347298-7kqrl3rv	559	47	MAP	MAP	NNP
cord-347298-7kqrl3rv	559	48	kinase	kinase	NN
cord-347298-7kqrl3rv	559	49	cascades	cascade	NNS
cord-347298-7kqrl3rv	560	1	(	(	-LRB-
cord-347298-7kqrl3rv	560	2	Heinrich	Heinrich	NNP
cord-347298-7kqrl3rv	560	3	et	et	NNP
cord-347298-7kqrl3rv	560	4	al	al	NNP
cord-347298-7kqrl3rv	560	5	.	.	NNP
cord-347298-7kqrl3rv	560	6	2003	2003	CD
cord-347298-7kqrl3rv	560	7	)	)	-RRB-
cord-347298-7kqrl3rv	560	8	.	.	.
cord-347298-7kqrl3rv	561	1	In	in	IN
cord-347298-7kqrl3rv	561	2	addition	addition	NN
cord-347298-7kqrl3rv	561	3	to	to	IN
cord-347298-7kqrl3rv	561	4	their	-PRON-	PRP$
cord-347298-7kqrl3rv	561	5	functions	function	NNS
cord-347298-7kqrl3rv	561	6	in	in	IN
cord-347298-7kqrl3rv	561	7	inflammation	inflammation	NN
cord-347298-7kqrl3rv	561	8	and	and	CC
cord-347298-7kqrl3rv	561	9	the	the	DT
cord-347298-7kqrl3rv	561	10	immune	immune	JJ
cord-347298-7kqrl3rv	561	11	response	response	NN
cord-347298-7kqrl3rv	561	12	,	,	,
cord-347298-7kqrl3rv	561	13	these	these	DT
cord-347298-7kqrl3rv	561	14	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	561	15	play	play	VBP
cord-347298-7kqrl3rv	561	16	crucial	crucial	JJ
cord-347298-7kqrl3rv	561	17	roles	role	NNS
cord-347298-7kqrl3rv	561	18	in	in	IN
cord-347298-7kqrl3rv	561	19	hematopoiesis	hematopoiesis	NN
cord-347298-7kqrl3rv	561	20	,	,	,
cord-347298-7kqrl3rv	561	21	liver	liver	NN
cord-347298-7kqrl3rv	561	22	and	and	CC
cord-347298-7kqrl3rv	561	23	neuronal	neuronal	JJ
cord-347298-7kqrl3rv	561	24	regeneration	regeneration	NN
cord-347298-7kqrl3rv	561	25	,	,	,
cord-347298-7kqrl3rv	561	26	embryonic	embryonic	JJ
cord-347298-7kqrl3rv	561	27	development	development	NN
cord-347298-7kqrl3rv	561	28	,	,	,
cord-347298-7kqrl3rv	561	29	and	and	CC
cord-347298-7kqrl3rv	561	30	fertility	fertility	NN
cord-347298-7kqrl3rv	561	31	.	.	.
cord-347298-7kqrl3rv	562	1	Members	member	NNS
cord-347298-7kqrl3rv	562	2	of	of	IN
cord-347298-7kqrl3rv	562	3	this	this	DT
cord-347298-7kqrl3rv	562	4	family	family	NN
cord-347298-7kqrl3rv	562	5	that	that	WDT
cord-347298-7kqrl3rv	562	6	have	have	VBP
cord-347298-7kqrl3rv	562	7	been	be	VBN
cord-347298-7kqrl3rv	562	8	detected	detect	VBN
cord-347298-7kqrl3rv	562	9	in	in	IN
cord-347298-7kqrl3rv	562	10	the	the	DT
cord-347298-7kqrl3rv	562	11	testis	testis	NN
cord-347298-7kqrl3rv	562	12	are	be	VBP
cord-347298-7kqrl3rv	562	13	leukemia	leukemia	NN
cord-347298-7kqrl3rv	562	14	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	562	15	factor	factor	NN
cord-347298-7kqrl3rv	562	16	,	,	,
cord-347298-7kqrl3rv	562	17	oncostatin	oncostatin	NNP
cord-347298-7kqrl3rv	562	18	M	M	NNP
cord-347298-7kqrl3rv	562	19	,	,	,
cord-347298-7kqrl3rv	562	20	ciliary	ciliary	JJ
cord-347298-7kqrl3rv	562	21	neurotropic	neurotropic	NNP
cord-347298-7kqrl3rv	562	22	factor	factor	NN
cord-347298-7kqrl3rv	562	23	,	,	,
cord-347298-7kqrl3rv	562	24	IL11	IL11	NNP
cord-347298-7kqrl3rv	562	25	,	,	,
cord-347298-7kqrl3rv	562	26	and	and	CC
cord-347298-7kqrl3rv	562	27	IL6	IL6	NNP
cord-347298-7kqrl3rv	562	28	itself	-PRON-	PRP
cord-347298-7kqrl3rv	562	29	(	(	-LRB-
cord-347298-7kqrl3rv	562	30	de	de	FW
cord-347298-7kqrl3rv	562	31	Miguel	Miguel	NNP
cord-347298-7kqrl3rv	562	32	et	et	NNP
cord-347298-7kqrl3rv	562	33	al	al	NNP
cord-347298-7kqrl3rv	562	34	.	.	.
cord-347298-7kqrl3rv	562	35	1996	1996	CD
cord-347298-7kqrl3rv	562	36	(	(	-LRB-
cord-347298-7kqrl3rv	562	37	de	de	IN
cord-347298-7kqrl3rv	562	38	Miguel	Miguel	NNP
cord-347298-7kqrl3rv	562	39	et	et	NNP
cord-347298-7kqrl3rv	562	40	al	al	NNP
cord-347298-7kqrl3rv	562	41	.	.	NNP
cord-347298-7kqrl3rv	562	42	,	,	,
cord-347298-7kqrl3rv	562	43	1997	1997	CD
cord-347298-7kqrl3rv	562	44	Du	Du	NNP
cord-347298-7kqrl3rv	562	45	et	et	FW
cord-347298-7kqrl3rv	562	46	al	al	NNP
cord-347298-7kqrl3rv	562	47	.	.	.
cord-347298-7kqrl3rv	562	48	1996	1996	CD
cord-347298-7kqrl3rv	562	49	;	;	:
cord-347298-7kqrl3rv	562	50	Jenab	Jenab	NNP
cord-347298-7kqrl3rv	562	51	and	and	CC
cord-347298-7kqrl3rv	562	52	Morris	Morris	NNP
cord-347298-7kqrl3rv	562	53	1998	1998	CD
cord-347298-7kqrl3rv	562	54	;	;	:
cord-347298-7kqrl3rv	562	55	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	562	56	et	et	NNP
cord-347298-7kqrl3rv	562	57	al	al	NNP
cord-347298-7kqrl3rv	562	58	.	.	.
cord-347298-7kqrl3rv	562	59	1994	1994	CD
cord-347298-7kqrl3rv	562	60	;	;	:
cord-347298-7kqrl3rv	562	61	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	562	62	et	et	NNP
cord-347298-7kqrl3rv	562	63	al	al	NNP
cord-347298-7kqrl3rv	562	64	.	.	.
cord-347298-7kqrl3rv	562	65	1997	1997	CD
cord-347298-7kqrl3rv	562	66	)	)	-RRB-
cord-347298-7kqrl3rv	562	67	.	.	.
cord-347298-7kqrl3rv	563	1	The	the	DT
cord-347298-7kqrl3rv	563	2	principal	principal	JJ
cord-347298-7kqrl3rv	563	3	roles	role	NNS
cord-347298-7kqrl3rv	563	4	of	of	IN
cord-347298-7kqrl3rv	563	5	most	most	JJS
cord-347298-7kqrl3rv	563	6	of	of	IN
cord-347298-7kqrl3rv	563	7	these	these	DT
cord-347298-7kqrl3rv	563	8	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	563	9	in	in	IN
cord-347298-7kqrl3rv	563	10	the	the	DT
cord-347298-7kqrl3rv	563	11	testis	testis	NN
cord-347298-7kqrl3rv	563	12	appear	appear	VBP
cord-347298-7kqrl3rv	563	13	to	to	TO
cord-347298-7kqrl3rv	563	14	lie	lie	VB
cord-347298-7kqrl3rv	563	15	in	in	IN
cord-347298-7kqrl3rv	563	16	regulating	regulate	VBG
cord-347298-7kqrl3rv	563	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	563	18	cell	cell	NN
cord-347298-7kqrl3rv	563	19	development	development	NN
cord-347298-7kqrl3rv	563	20	and	and	CC
cord-347298-7kqrl3rv	563	21	the	the	DT
cord-347298-7kqrl3rv	563	22	onset	onset	NN
cord-347298-7kqrl3rv	563	23	of	of	IN
cord-347298-7kqrl3rv	563	24	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	563	25	.	.	.
cord-347298-7kqrl3rv	564	1	A	a	DT
cord-347298-7kqrl3rv	564	2	role	role	NN
cord-347298-7kqrl3rv	564	3	in	in	IN
cord-347298-7kqrl3rv	564	4	testicular	testicular	JJ
cord-347298-7kqrl3rv	564	5	immunology	immunology	NN
cord-347298-7kqrl3rv	564	6	is	be	VBZ
cord-347298-7kqrl3rv	564	7	most	most	RBS
cord-347298-7kqrl3rv	564	8	likely	likely	JJ
cord-347298-7kqrl3rv	564	9	for	for	IN
cord-347298-7kqrl3rv	564	10	IL6	IL6	NNP
cord-347298-7kqrl3rv	564	11	,	,	,
cord-347298-7kqrl3rv	564	12	which	which	WDT
cord-347298-7kqrl3rv	564	13	possesses	possess	VBZ
cord-347298-7kqrl3rv	564	14	both	both	DT
cord-347298-7kqrl3rv	564	15	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	564	16	and	and	CC
cord-347298-7kqrl3rv	564	17	anti	anti	JJ
cord-347298-7kqrl3rv	564	18	-	-	JJ
cord-347298-7kqrl3rv	564	19	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	564	20	properties	property	NNS
cord-347298-7kqrl3rv	564	21	,	,	,
cord-347298-7kqrl3rv	564	22	and	and	CC
cord-347298-7kqrl3rv	564	23	regulates	regulate	VBZ
cord-347298-7kqrl3rv	564	24	the	the	DT
cord-347298-7kqrl3rv	564	25	acute	acute	JJ
cord-347298-7kqrl3rv	564	26	-	-	HYPH
cord-347298-7kqrl3rv	564	27	phase	phase	NN
cord-347298-7kqrl3rv	564	28	response	response	NN
cord-347298-7kqrl3rv	564	29	as	as	RB
cord-347298-7kqrl3rv	564	30	well	well	RB
cord-347298-7kqrl3rv	564	31	as	as	IN
cord-347298-7kqrl3rv	564	32	several	several	JJ
cord-347298-7kqrl3rv	564	33	aspects	aspect	NNS
cord-347298-7kqrl3rv	564	34	of	of	IN
cord-347298-7kqrl3rv	564	35	immune	immune	JJ
cord-347298-7kqrl3rv	564	36	cell	cell	NN
cord-347298-7kqrl3rv	564	37	development	development	NN
cord-347298-7kqrl3rv	564	38	and	and	CC
cord-347298-7kqrl3rv	564	39	activity	activity	NN
cord-347298-7kqrl3rv	564	40	(	(	-LRB-
cord-347298-7kqrl3rv	564	41	Kopf	Kopf	NNP
cord-347298-7kqrl3rv	564	42	et	et	NNP
cord-347298-7kqrl3rv	564	43	al	al	NNP
cord-347298-7kqrl3rv	564	44	.	.	.
cord-347298-7kqrl3rv	564	45	1994	1994	CD
cord-347298-7kqrl3rv	564	46	;	;	.
cord-347298-7kqrl3rv	565	1	Tilg	Tilg	NNP
cord-347298-7kqrl3rv	565	2	et	et	NNP
cord-347298-7kqrl3rv	565	3	al	al	NNP
cord-347298-7kqrl3rv	565	4	.	.	.
cord-347298-7kqrl3rv	565	5	1997	1997	CD
cord-347298-7kqrl3rv	565	6	)	)	-RRB-
cord-347298-7kqrl3rv	565	7	.	.	.
cord-347298-7kqrl3rv	566	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	566	2	cells	cell	NNS
cord-347298-7kqrl3rv	566	3	,	,	,
cord-347298-7kqrl3rv	566	4	Leydig	leydig	NN
cord-347298-7kqrl3rv	566	5	cells	cell	NNS
cord-347298-7kqrl3rv	566	6	,	,	,
cord-347298-7kqrl3rv	566	7	and	and	CC
cord-347298-7kqrl3rv	566	8	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	566	9	cells	cell	NNS
cord-347298-7kqrl3rv	566	10	have	have	VBP
cord-347298-7kqrl3rv	566	11	been	be	VBN
cord-347298-7kqrl3rv	566	12	shown	show	VBN
cord-347298-7kqrl3rv	566	13	to	to	TO
cord-347298-7kqrl3rv	566	14	produce	produce	VB
cord-347298-7kqrl3rv	566	15	IL6	il6	NN
cord-347298-7kqrl3rv	567	1	in	in	IN
cord-347298-7kqrl3rv	567	2	vitro	vitro	FW
cord-347298-7kqrl3rv	568	1	(	(	-LRB-
cord-347298-7kqrl3rv	568	2	Cudicini	Cudicini	NNP
cord-347298-7kqrl3rv	568	3	et	et	NNP
cord-347298-7kqrl3rv	568	4	al	al	NNP
cord-347298-7kqrl3rv	568	5	.	.	.
cord-347298-7kqrl3rv	569	1	1997b	1997b	CD
cord-347298-7kqrl3rv	569	2	;	;	:
cord-347298-7kqrl3rv	570	1	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	570	2	et	et	NNP
cord-347298-7kqrl3rv	570	3	al	al	NNP
cord-347298-7kqrl3rv	570	4	.	.	.
cord-347298-7kqrl3rv	570	5	1994	1994	CD
cord-347298-7kqrl3rv	571	1	;	;	:
cord-347298-7kqrl3rv	571	2	Syed	Syed	NNP
cord-347298-7kqrl3rv	571	3	et	et	NNP
cord-347298-7kqrl3rv	571	4	al	al	NNP
cord-347298-7kqrl3rv	571	5	.	.	.
cord-347298-7kqrl3rv	571	6	1993	1993	CD
cord-347298-7kqrl3rv	572	1	Syed	Syed	NNP
cord-347298-7kqrl3rv	572	2	et	et	NNP
cord-347298-7kqrl3rv	572	3	al	al	NNP
cord-347298-7kqrl3rv	572	4	.	.	NNP
cord-347298-7kqrl3rv	572	5	,	,	,
cord-347298-7kqrl3rv	572	6	1995	1995	CD
cord-347298-7kqrl3rv	572	7	.	.	.
cord-347298-7kqrl3rv	573	1	In	in	IN
cord-347298-7kqrl3rv	573	2	rat	rat	NN
cord-347298-7kqrl3rv	573	3	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	573	4	cells	cell	NNS
cord-347298-7kqrl3rv	573	5	,	,	,
cord-347298-7kqrl3rv	573	6	IL6	il6	NN
cord-347298-7kqrl3rv	573	7	production	production	NN
cord-347298-7kqrl3rv	573	8	is	be	VBZ
cord-347298-7kqrl3rv	573	9	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	573	10	by	by	IN
cord-347298-7kqrl3rv	573	11	FSH	fsh	NN
cord-347298-7kqrl3rv	573	12	,	,	,
cord-347298-7kqrl3rv	573	13	testosterone	testosterone	NN
cord-347298-7kqrl3rv	573	14	,	,	,
cord-347298-7kqrl3rv	573	15	phagocytosis	phagocytosis	NN
cord-347298-7kqrl3rv	573	16	,	,	,
cord-347298-7kqrl3rv	573	17	and	and	CC
cord-347298-7kqrl3rv	573	18	other	other	JJ
cord-347298-7kqrl3rv	573	19	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	573	20	stimuli	stimulus	NNS
cord-347298-7kqrl3rv	573	21	,	,	,
cord-347298-7kqrl3rv	573	22	including	include	VBG
cord-347298-7kqrl3rv	573	23	IL1	IL1	NNP
cord-347298-7kqrl3rv	573	24	,	,	,
cord-347298-7kqrl3rv	573	25	IL1	IL1	NNP
cord-347298-7kqrl3rv	573	26	,	,	,
cord-347298-7kqrl3rv	573	27	TNF	TNF	NNP
cord-347298-7kqrl3rv	573	28	,	,	,
cord-347298-7kqrl3rv	573	29	and	and	CC
cord-347298-7kqrl3rv	573	30	LPS	LPS	NNP
cord-347298-7kqrl3rv	573	31	(	(	-LRB-
cord-347298-7kqrl3rv	573	32	Cudicini	Cudicini	NNP
cord-347298-7kqrl3rv	573	33	et	et	NNP
cord-347298-7kqrl3rv	573	34	al	al	NNP
cord-347298-7kqrl3rv	573	35	.	.	.
cord-347298-7kqrl3rv	574	1	1997a	1997a	CD
cord-347298-7kqrl3rv	574	2	,	,	,
cord-347298-7kqrl3rv	574	3	b	b	LS
cord-347298-7kqrl3rv	574	4	;	;	:
cord-347298-7kqrl3rv	574	5	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	574	6	et	et	NNP
cord-347298-7kqrl3rv	574	7	al	al	NNP
cord-347298-7kqrl3rv	574	8	.	.	.
cord-347298-7kqrl3rv	575	1	1994	1994	CD
cord-347298-7kqrl3rv	576	1	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	576	2	et	et	NNP
cord-347298-7kqrl3rv	576	3	al	al	NNP
cord-347298-7kqrl3rv	576	4	.	.	.
cord-347298-7kqrl3rv	577	1	,	,	,
cord-347298-7kqrl3rv	577	2	1995	1995	CD
cord-347298-7kqrl3rv	577	3	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	577	4	et	et	NNP
cord-347298-7kqrl3rv	577	5	al	al	NNP
cord-347298-7kqrl3rv	577	6	.	.	.
cord-347298-7kqrl3rv	578	1	1997	1997	CD
cord-347298-7kqrl3rv	578	2	;	;	:
cord-347298-7kqrl3rv	578	3	Syed	Syed	NNP
cord-347298-7kqrl3rv	578	4	et	et	NNP
cord-347298-7kqrl3rv	578	5	al	al	NNP
cord-347298-7kqrl3rv	578	6	.	.	NNP
cord-347298-7kqrl3rv	578	7	1995	1995	CD
cord-347298-7kqrl3rv	578	8	)	)	-RRB-
cord-347298-7kqrl3rv	578	9	.	.	.
cord-347298-7kqrl3rv	579	1	Production	production	NN
cord-347298-7kqrl3rv	579	2	of	of	IN
cord-347298-7kqrl3rv	579	3	IL6	IL6	NNP
cord-347298-7kqrl3rv	579	4	by	by	IN
cord-347298-7kqrl3rv	579	5	cultured	cultured	JJ
cord-347298-7kqrl3rv	579	6	mouse	mouse	NN
cord-347298-7kqrl3rv	580	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	580	2	cells	cell	NNS
cord-347298-7kqrl3rv	580	3	is	be	VBZ
cord-347298-7kqrl3rv	580	4	inhibited	inhibit	VBN
cord-347298-7kqrl3rv	580	5	by	by	IN
cord-347298-7kqrl3rv	580	6	INF	INF	NNP
cord-347298-7kqrl3rv	580	7	(	(	-LRB-
cord-347298-7kqrl3rv	580	8	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	580	9	et	et	NNP
cord-347298-7kqrl3rv	580	10	al	al	NNP
cord-347298-7kqrl3rv	580	11	.	.	.
cord-347298-7kqrl3rv	580	12	2000	2000	CD
cord-347298-7kqrl3rv	580	13	;	;	:
cord-347298-7kqrl3rv	580	14	Stéphan	Stéphan	NNP
cord-347298-7kqrl3rv	580	15	et	et	NNP
cord-347298-7kqrl3rv	580	16	al	al	NNP
cord-347298-7kqrl3rv	580	17	.	.	.
cord-347298-7kqrl3rv	580	18	1997	1997	CD
cord-347298-7kqrl3rv	580	19	)	)	-RRB-
cord-347298-7kqrl3rv	580	20	.	.	.
cord-347298-7kqrl3rv	581	1	Within	within	IN
cord-347298-7kqrl3rv	581	2	the	the	DT
cord-347298-7kqrl3rv	581	3	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	581	4	epithelium	epithelium	NN
cord-347298-7kqrl3rv	581	5	,	,	,
cord-347298-7kqrl3rv	581	6	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	581	7	production	production	NN
cord-347298-7kqrl3rv	581	8	of	of	IN
cord-347298-7kqrl3rv	581	9	IL6	IL6	NNP
cord-347298-7kqrl3rv	581	10	follows	follow	VBZ
cord-347298-7kqrl3rv	581	11	a	a	DT
cord-347298-7kqrl3rv	581	12	cyclical	cyclical	JJ
cord-347298-7kqrl3rv	581	13	pattern	pattern	NN
cord-347298-7kqrl3rv	581	14	that	that	WDT
cord-347298-7kqrl3rv	581	15	corresponds	correspond	VBZ
cord-347298-7kqrl3rv	581	16	with	with	IN
cord-347298-7kqrl3rv	581	17	the	the	DT
cord-347298-7kqrl3rv	581	18	changes	change	NNS
cord-347298-7kqrl3rv	581	19	in	in	IN
cord-347298-7kqrl3rv	581	20	the	the	DT
cord-347298-7kqrl3rv	581	21	stages	stage	NNS
cord-347298-7kqrl3rv	581	22	of	of	IN
cord-347298-7kqrl3rv	581	23	the	the	DT
cord-347298-7kqrl3rv	581	24	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	581	25	cycle	cycle	NN
cord-347298-7kqrl3rv	581	26	,	,	,
cord-347298-7kqrl3rv	581	27	most	most	RBS
cord-347298-7kqrl3rv	581	28	probably	probably	RB
cord-347298-7kqrl3rv	581	29	under	under	IN
cord-347298-7kqrl3rv	581	30	the	the	DT
cord-347298-7kqrl3rv	581	31	influence	influence	NN
cord-347298-7kqrl3rv	581	32	of	of	IN
cord-347298-7kqrl3rv	581	33	IL1	IL1	NNP
cord-347298-7kqrl3rv	581	34	and	and	CC
cord-347298-7kqrl3rv	581	35	FSH	FSH	NNP
cord-347298-7kqrl3rv	581	36	(	(	-LRB-
cord-347298-7kqrl3rv	581	37	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	581	38	et	et	NNP
cord-347298-7kqrl3rv	581	39	al	al	NNP
cord-347298-7kqrl3rv	581	40	.	.	.
cord-347298-7kqrl3rv	582	1	1995	1995	CD
cord-347298-7kqrl3rv	582	2	;	;	:
cord-347298-7kqrl3rv	582	3	Syed	Syed	NNP
cord-347298-7kqrl3rv	582	4	et	et	NNP
cord-347298-7kqrl3rv	582	5	al	al	NNP
cord-347298-7kqrl3rv	582	6	.	.	.
cord-347298-7kqrl3rv	582	7	1993	1993	CD
cord-347298-7kqrl3rv	583	1	Syed	Syed	NNP
cord-347298-7kqrl3rv	583	2	et	et	NNP
cord-347298-7kqrl3rv	583	3	al	al	NNP
cord-347298-7kqrl3rv	583	4	.	.	NNP
cord-347298-7kqrl3rv	583	5	,	,	,
cord-347298-7kqrl3rv	583	6	1995	1995	CD
cord-347298-7kqrl3rv	583	7	.	.	.
cord-347298-7kqrl3rv	584	1	Both	both	DT
cord-347298-7kqrl3rv	584	2	the	the	DT
cord-347298-7kqrl3rv	584	3	IL6-specific	il6-specific	JJ
cord-347298-7kqrl3rv	584	4	receptor	receptor	NN
cord-347298-7kqrl3rv	584	5	subunit	subunit	NN
cord-347298-7kqrl3rv	584	6	(	(	-LRB-
cord-347298-7kqrl3rv	584	7	IL6R	IL6R	NNP
cord-347298-7kqrl3rv	584	8	)	)	-RRB-
cord-347298-7kqrl3rv	584	9	and	and	CC
cord-347298-7kqrl3rv	584	10	the	the	DT
cord-347298-7kqrl3rv	584	11	gp130	gp130	NNP
cord-347298-7kqrl3rv	584	12	mRNA	mRNA	NNP
cord-347298-7kqrl3rv	584	13	are	be	VBP
cord-347298-7kqrl3rv	584	14	expressed	express	VBN
cord-347298-7kqrl3rv	584	15	in	in	IN
cord-347298-7kqrl3rv	584	16	rat	rat	NN
cord-347298-7kqrl3rv	584	17	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	584	18	cells	cell	NNS
cord-347298-7kqrl3rv	584	19	,	,	,
cord-347298-7kqrl3rv	584	20	and	and	CC
cord-347298-7kqrl3rv	584	21	are	be	VBP
cord-347298-7kqrl3rv	584	22	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	584	23	by	by	IN
cord-347298-7kqrl3rv	584	24	IL1	IL1	NNP
cord-347298-7kqrl3rv	584	25	and	and	CC
cord-347298-7kqrl3rv	584	26	IL6	IL6	NNP
cord-347298-7kqrl3rv	584	27	,	,	,
cord-347298-7kqrl3rv	584	28	but	but	CC
cord-347298-7kqrl3rv	584	29	only	only	RB
cord-347298-7kqrl3rv	584	30	the	the	DT
cord-347298-7kqrl3rv	584	31	IL6R	IL6R	NNP
cord-347298-7kqrl3rv	584	32	subunit	subunit	NN
cord-347298-7kqrl3rv	584	33	is	be	VBZ
cord-347298-7kqrl3rv	584	34	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	584	35	by	by	IN
cord-347298-7kqrl3rv	584	36	FSH	fsh	NN
cord-347298-7kqrl3rv	584	37	(	(	-LRB-
cord-347298-7kqrl3rv	584	38	Fujisawa	Fujisawa	NNP
cord-347298-7kqrl3rv	584	39	et	et	FW
cord-347298-7kqrl3rv	584	40	al	al	NNP
cord-347298-7kqrl3rv	584	41	.	.	.
cord-347298-7kqrl3rv	584	42	2002	2002	CD
cord-347298-7kqrl3rv	584	43	)	)	-RRB-
cord-347298-7kqrl3rv	584	44	.	.	.
cord-347298-7kqrl3rv	585	1	IL6	il6	NN
cord-347298-7kqrl3rv	585	2	increases	increase	VBZ
cord-347298-7kqrl3rv	585	3	basal	basal	NN
cord-347298-7kqrl3rv	585	4	and	and	CC
cord-347298-7kqrl3rv	585	5	FSH	fsh	NN
cord-347298-7kqrl3rv	585	6	-	-	HYPH
cord-347298-7kqrl3rv	585	7	induced	induce	VBN
cord-347298-7kqrl3rv	585	8	transferrin	transferrin	NN
cord-347298-7kqrl3rv	585	9	and	and	CC
cord-347298-7kqrl3rv	585	10	cyclic	cyclic	JJ
cord-347298-7kqrl3rv	585	11	GMP	GMP	NNP
cord-347298-7kqrl3rv	585	12	secretion	secretion	NN
cord-347298-7kqrl3rv	585	13	by	by	IN
cord-347298-7kqrl3rv	585	14	the	the	DT
cord-347298-7kqrl3rv	585	15	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	585	16	cell	cell	NN
cord-347298-7kqrl3rv	585	17	,	,	,
cord-347298-7kqrl3rv	585	18	and	and	CC
cord-347298-7kqrl3rv	585	19	inhibits	inhibit	VBZ
cord-347298-7kqrl3rv	585	20	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	585	21	DNA	dna	NN
cord-347298-7kqrl3rv	585	22	synthesis	synthesis	NN
cord-347298-7kqrl3rv	585	23	in	in	IN
cord-347298-7kqrl3rv	585	24	preleptotene	preleptotene	NNP
cord-347298-7kqrl3rv	585	25	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	585	26	(	(	-LRB-
cord-347298-7kqrl3rv	585	27	Boockfor	Boockfor	NNP
cord-347298-7kqrl3rv	585	28	and	and	CC
cord-347298-7kqrl3rv	585	29	Schwarz	Schwarz	NNP
cord-347298-7kqrl3rv	585	30	1991	1991	CD
cord-347298-7kqrl3rv	585	31	;	;	:
cord-347298-7kqrl3rv	586	1	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	586	2	et	et	NNP
cord-347298-7kqrl3rv	586	3	al	al	NNP
cord-347298-7kqrl3rv	586	4	.	.	.
cord-347298-7kqrl3rv	587	1	1995	1995	CD
cord-347298-7kqrl3rv	587	2	;	;	:
cord-347298-7kqrl3rv	587	3	Hoeben	Hoeben	NNP
cord-347298-7kqrl3rv	587	4	et	et	NNP
cord-347298-7kqrl3rv	587	5	al	al	NNP
cord-347298-7kqrl3rv	587	6	.	.	.
cord-347298-7kqrl3rv	587	7	1997	1997	CD
cord-347298-7kqrl3rv	587	8	)	)	-RRB-
cord-347298-7kqrl3rv	587	9	.	.	.
cord-347298-7kqrl3rv	588	1	In	in	IN
cord-347298-7kqrl3rv	588	2	models	model	NNS
cord-347298-7kqrl3rv	588	3	of	of	IN
cord-347298-7kqrl3rv	588	4	EAO	EAO	NNP
cord-347298-7kqrl3rv	588	5	,	,	,
cord-347298-7kqrl3rv	588	6	IL6	IL6	NNP
cord-347298-7kqrl3rv	588	7	appears	appear	VBZ
cord-347298-7kqrl3rv	588	8	to	to	TO
cord-347298-7kqrl3rv	588	9	play	play	VB
cord-347298-7kqrl3rv	588	10	an	an	DT
cord-347298-7kqrl3rv	588	11	ameliorative	ameliorative	JJ
cord-347298-7kqrl3rv	588	12	or	or	CC
cord-347298-7kqrl3rv	588	13	protective	protective	JJ
cord-347298-7kqrl3rv	588	14	role	role	NN
cord-347298-7kqrl3rv	588	15	within	within	IN
cord-347298-7kqrl3rv	588	16	the	the	DT
cord-347298-7kqrl3rv	588	17	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	588	18	epithelium	epithelium	NN
cord-347298-7kqrl3rv	588	19	(	(	-LRB-
cord-347298-7kqrl3rv	588	20	Li	Li	NNP
cord-347298-7kqrl3rv	588	21	et	et	NNP
cord-347298-7kqrl3rv	588	22	al	al	NNP
cord-347298-7kqrl3rv	588	23	.	.	NNP
cord-347298-7kqrl3rv	588	24	2002	2002	CD
cord-347298-7kqrl3rv	588	25	;	;	:
cord-347298-7kqrl3rv	588	26	Rival	Rival	NNP
cord-347298-7kqrl3rv	588	27	et	et	NNP
cord-347298-7kqrl3rv	588	28	al	al	NNP
cord-347298-7kqrl3rv	588	29	.	.	NNP
cord-347298-7kqrl3rv	588	30	2006b	2006b	CD
cord-347298-7kqrl3rv	588	31	)	)	-RRB-
cord-347298-7kqrl3rv	588	32	.	.	.
cord-347298-7kqrl3rv	589	1	Leydig	leydig	NN
cord-347298-7kqrl3rv	589	2	cells	cell	NNS
cord-347298-7kqrl3rv	589	3	are	be	VBP
cord-347298-7kqrl3rv	589	4	also	also	RB
cord-347298-7kqrl3rv	589	5	active	active	JJ
cord-347298-7kqrl3rv	589	6	producers	producer	NNS
cord-347298-7kqrl3rv	589	7	of	of	IN
cord-347298-7kqrl3rv	589	8	IL6	il6	NN
cord-347298-7kqrl3rv	589	9	following	follow	VBG
cord-347298-7kqrl3rv	589	10	stimulation	stimulation	NN
cord-347298-7kqrl3rv	589	11	by	by	IN
cord-347298-7kqrl3rv	589	12	LH	LH	NNP
cord-347298-7kqrl3rv	589	13	,	,	,
cord-347298-7kqrl3rv	589	14	LPS	LPS	NNP
cord-347298-7kqrl3rv	589	15	,	,	,
cord-347298-7kqrl3rv	589	16	or	or	CC
cord-347298-7kqrl3rv	589	17	IL1	IL1	NNP
cord-347298-7kqrl3rv	589	18	in	in	IN
cord-347298-7kqrl3rv	589	19	vitro	vitro	FW
cord-347298-7kqrl3rv	589	20	,	,	,
cord-347298-7kqrl3rv	589	21	and	and	CC
cord-347298-7kqrl3rv	589	22	evidence	evidence	NN
cord-347298-7kqrl3rv	589	23	suggests	suggest	VBZ
cord-347298-7kqrl3rv	589	24	that	that	IN
cord-347298-7kqrl3rv	589	25	these	these	DT
cord-347298-7kqrl3rv	589	26	cells	cell	NNS
cord-347298-7kqrl3rv	589	27	actually	actually	RB
cord-347298-7kqrl3rv	589	28	may	may	MD
cord-347298-7kqrl3rv	589	29	be	be	VB
cord-347298-7kqrl3rv	589	30	the	the	DT
cord-347298-7kqrl3rv	589	31	major	major	JJ
cord-347298-7kqrl3rv	589	32	testicular	testicular	JJ
cord-347298-7kqrl3rv	589	33	source	source	NN
cord-347298-7kqrl3rv	589	34	(	(	-LRB-
cord-347298-7kqrl3rv	589	35	Boockfor	Boockfor	NNP
cord-347298-7kqrl3rv	589	36	et	et	NNP
cord-347298-7kqrl3rv	589	37	al	al	NNP
cord-347298-7kqrl3rv	589	38	.	.	.
cord-347298-7kqrl3rv	589	39	1994	1994	CD
cord-347298-7kqrl3rv	589	40	;	;	:
cord-347298-7kqrl3rv	589	41	Cudicini	Cudicini	NNP
cord-347298-7kqrl3rv	589	42	et	et	NNP
cord-347298-7kqrl3rv	589	43	al	al	NNP
cord-347298-7kqrl3rv	589	44	.	.	NNP
cord-347298-7kqrl3rv	589	45	1997b	1997b	CD
cord-347298-7kqrl3rv	589	46	;	;	:
cord-347298-7kqrl3rv	590	1	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	590	2	et	et	NNP
cord-347298-7kqrl3rv	590	3	al	al	NNP
cord-347298-7kqrl3rv	590	4	.	.	.
cord-347298-7kqrl3rv	591	1	1994	1994	CD
cord-347298-7kqrl3rv	592	1	Okuda	Okuda	NNP
cord-347298-7kqrl3rv	592	2	et	et	NNP
cord-347298-7kqrl3rv	592	3	al	al	NNP
cord-347298-7kqrl3rv	592	4	.	.	NNP
cord-347298-7kqrl3rv	592	5	,	,	,
cord-347298-7kqrl3rv	592	6	1995	1995	CD
cord-347298-7kqrl3rv	592	7	.	.	.
cord-347298-7kqrl3rv	593	1	Several	several	JJ
cord-347298-7kqrl3rv	593	2	studies	study	NNS
cord-347298-7kqrl3rv	593	3	have	have	VBP
cord-347298-7kqrl3rv	593	4	implicated	implicate	VBN
cord-347298-7kqrl3rv	593	5	IL10	IL10	NNP
cord-347298-7kqrl3rv	593	6	as	as	IN
cord-347298-7kqrl3rv	593	7	a	a	DT
cord-347298-7kqrl3rv	593	8	key	key	JJ
cord-347298-7kqrl3rv	593	9	player	player	NN
cord-347298-7kqrl3rv	593	10	in	in	IN
cord-347298-7kqrl3rv	593	11	testicular	testicular	JJ
cord-347298-7kqrl3rv	593	12	immunology	immunology	NN
cord-347298-7kqrl3rv	593	13	.	.	.
cord-347298-7kqrl3rv	594	1	Testicular	testicular	JJ
cord-347298-7kqrl3rv	594	2	IL10	IL10	NNP
cord-347298-7kqrl3rv	594	3	production	production	NN
cord-347298-7kqrl3rv	594	4	is	be	VBZ
cord-347298-7kqrl3rv	594	5	preferentially	preferentially	RB
cord-347298-7kqrl3rv	594	6	induced	induce	VBN
cord-347298-7kqrl3rv	594	7	by	by	IN
cord-347298-7kqrl3rv	594	8	systemic	systemic	JJ
cord-347298-7kqrl3rv	594	9	LPS	LPS	NNP
cord-347298-7kqrl3rv	594	10	treatment	treatment	NN
cord-347298-7kqrl3rv	594	11	in	in	IN
cord-347298-7kqrl3rv	594	12	the	the	DT
cord-347298-7kqrl3rv	594	13	adult	adult	NN
cord-347298-7kqrl3rv	594	14	rat	rat	NN
cord-347298-7kqrl3rv	594	15	testis	testis	NN
cord-347298-7kqrl3rv	594	16	(	(	-LRB-
cord-347298-7kqrl3rv	594	17	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	594	18	et	et	NNP
cord-347298-7kqrl3rv	594	19	al	al	NNP
cord-347298-7kqrl3rv	594	20	.	.	NNP
cord-347298-7kqrl3rv	594	21	2005	2005	CD
cord-347298-7kqrl3rv	594	22	)	)	-RRB-
cord-347298-7kqrl3rv	594	23	,	,	,
cord-347298-7kqrl3rv	594	24	and	and	CC
cord-347298-7kqrl3rv	594	25	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	594	26	and	and	CC
cord-347298-7kqrl3rv	594	27	T	t	NN
cord-347298-7kqrl3rv	594	28	cells	cell	NNS
cord-347298-7kqrl3rv	594	29	isolated	isolate	VBN
cord-347298-7kqrl3rv	594	30	from	from	IN
cord-347298-7kqrl3rv	594	31	the	the	DT
cord-347298-7kqrl3rv	594	32	rat	rat	NN
cord-347298-7kqrl3rv	594	33	testis	testis	NN
cord-347298-7kqrl3rv	594	34	constitutively	constitutively	RB
cord-347298-7kqrl3rv	594	35	produce	produce	VBP
cord-347298-7kqrl3rv	594	36	IL10	IL10	NNP
cord-347298-7kqrl3rv	594	37	,	,	,
cord-347298-7kqrl3rv	594	38	which	which	WDT
cord-347298-7kqrl3rv	594	39	may	may	MD
cord-347298-7kqrl3rv	594	40	contribute	contribute	VB
cord-347298-7kqrl3rv	594	41	to	to	IN
cord-347298-7kqrl3rv	594	42	testicular	testicular	JJ
cord-347298-7kqrl3rv	594	43	immune	immune	JJ
cord-347298-7kqrl3rv	594	44	privilege	privilege	NN
cord-347298-7kqrl3rv	594	45	(	(	-LRB-
cord-347298-7kqrl3rv	594	46	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	594	47	,	,	,
cord-347298-7kqrl3rv	594	48	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	594	49	data	datum	NNS
cord-347298-7kqrl3rv	594	50	)	)	-RRB-
cord-347298-7kqrl3rv	594	51	.	.	.
cord-347298-7kqrl3rv	595	1	In	in	IN
cord-347298-7kqrl3rv	595	2	a	a	DT
cord-347298-7kqrl3rv	595	3	mouse	mouse	NN
cord-347298-7kqrl3rv	595	4	model	model	NN
cord-347298-7kqrl3rv	595	5	of	of	IN
cord-347298-7kqrl3rv	595	6	EAO	EAO	NNP
cord-347298-7kqrl3rv	595	7	,	,	,
cord-347298-7kqrl3rv	595	8	elevation	elevation	NN
cord-347298-7kqrl3rv	595	9	of	of	IN
cord-347298-7kqrl3rv	595	10	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	595	11	IL10	IL10	NNP
cord-347298-7kqrl3rv	595	12	levels	level	NNS
cord-347298-7kqrl3rv	595	13	by	by	IN
cord-347298-7kqrl3rv	595	14	adenoviral	adenoviral	NN
cord-347298-7kqrl3rv	595	15	-	-	HYPH
cord-347298-7kqrl3rv	595	16	mediated	mediate	VBN
cord-347298-7kqrl3rv	595	17	transfection	transfection	NN
cord-347298-7kqrl3rv	595	18	of	of	IN
cord-347298-7kqrl3rv	595	19	human	human	JJ
cord-347298-7kqrl3rv	595	20	IL10	IL10	NNP
cord-347298-7kqrl3rv	595	21	was	be	VBD
cord-347298-7kqrl3rv	595	22	found	find	VBN
cord-347298-7kqrl3rv	595	23	to	to	TO
cord-347298-7kqrl3rv	595	24	significantly	significantly	RB
cord-347298-7kqrl3rv	595	25	reduce	reduce	VB
cord-347298-7kqrl3rv	595	26	the	the	DT
cord-347298-7kqrl3rv	595	27	incidence	incidence	NN
cord-347298-7kqrl3rv	595	28	of	of	IN
cord-347298-7kqrl3rv	595	29	immune	immune	JJ
cord-347298-7kqrl3rv	595	30	activation	activation	NN
cord-347298-7kqrl3rv	595	31	,	,	,
cord-347298-7kqrl3rv	595	32	orchitis	orchitis	NN
cord-347298-7kqrl3rv	595	33	,	,	,
cord-347298-7kqrl3rv	595	34	and	and	CC
cord-347298-7kqrl3rv	595	35	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	595	36	damage	damage	NN
cord-347298-7kqrl3rv	596	1	(	(	-LRB-
cord-347298-7kqrl3rv	596	2	Watanabe	Watanabe	NNP
cord-347298-7kqrl3rv	596	3	et	et	NNP
cord-347298-7kqrl3rv	596	4	al	al	NNP
cord-347298-7kqrl3rv	596	5	.	.	NNP
cord-347298-7kqrl3rv	596	6	2005	2005	CD
cord-347298-7kqrl3rv	596	7	)	)	-RRB-
cord-347298-7kqrl3rv	596	8	.	.	.
cord-347298-7kqrl3rv	597	1	Although	although	IN
cord-347298-7kqrl3rv	597	2	male	male	JJ
cord-347298-7kqrl3rv	597	3	mice	mouse	NNS
cord-347298-7kqrl3rv	597	4	deficient	deficient	JJ
cord-347298-7kqrl3rv	597	5	in	in	IN
cord-347298-7kqrl3rv	597	6	IL10	IL10	NNP
cord-347298-7kqrl3rv	597	7	do	do	VBP
cord-347298-7kqrl3rv	597	8	not	not	RB
cord-347298-7kqrl3rv	597	9	show	show	VB
cord-347298-7kqrl3rv	597	10	evidence	evidence	NN
cord-347298-7kqrl3rv	597	11	of	of	IN
cord-347298-7kqrl3rv	597	12	male	male	JJ
cord-347298-7kqrl3rv	597	13	fertility	fertility	NN
cord-347298-7kqrl3rv	597	14	problems	problem	NNS
cord-347298-7kqrl3rv	597	15	,	,	,
cord-347298-7kqrl3rv	597	16	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	597	17	immune	immune	JJ
cord-347298-7kqrl3rv	597	18	responses	response	NNS
cord-347298-7kqrl3rv	597	19	have	have	VBP
cord-347298-7kqrl3rv	597	20	yet	yet	RB
cord-347298-7kqrl3rv	597	21	to	to	TO
cord-347298-7kqrl3rv	597	22	be	be	VB
cord-347298-7kqrl3rv	597	23	examined	examine	VBN
cord-347298-7kqrl3rv	597	24	in	in	IN
cord-347298-7kqrl3rv	597	25	these	these	DT
cord-347298-7kqrl3rv	597	26	animals	animal	NNS
cord-347298-7kqrl3rv	597	27	(	(	-LRB-
cord-347298-7kqrl3rv	597	28	Kühn	Kühn	NNP
cord-347298-7kqrl3rv	597	29	et	et	NNP
cord-347298-7kqrl3rv	597	30	al	al	NNP
cord-347298-7kqrl3rv	597	31	.	.	.
cord-347298-7kqrl3rv	597	32	1993	1993	CD
cord-347298-7kqrl3rv	597	33	)	)	-RRB-
cord-347298-7kqrl3rv	597	34	.	.	.
cord-347298-7kqrl3rv	598	1	11.10.4.2.6	11.10.4.2.6	CD
cord-347298-7kqrl3rv	598	2	Nitric	nitric	NN
cord-347298-7kqrl3rv	598	3	oxide	oxide	NN
cord-347298-7kqrl3rv	598	4	and	and	CC
cord-347298-7kqrl3rv	598	5	oxygen	oxygen	NN
cord-347298-7kqrl3rv	598	6	metabolites	metabolite	NNS
cord-347298-7kqrl3rv	598	7	Production	production	NN
cord-347298-7kqrl3rv	598	8	of	of	IN
cord-347298-7kqrl3rv	598	9	ROS	ROS	NNP
cord-347298-7kqrl3rv	598	10	,	,	,
cord-347298-7kqrl3rv	598	11	particularly	particularly	RB
cord-347298-7kqrl3rv	598	12	by	by	IN
cord-347298-7kqrl3rv	598	13	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	598	14	,	,	,
cord-347298-7kqrl3rv	598	15	is	be	VBZ
cord-347298-7kqrl3rv	598	16	an	an	DT
cord-347298-7kqrl3rv	598	17	important	important	JJ
cord-347298-7kqrl3rv	598	18	component	component	NN
cord-347298-7kqrl3rv	598	19	of	of	IN
cord-347298-7kqrl3rv	598	20	the	the	DT
cord-347298-7kqrl3rv	598	21	early	early	JJ
cord-347298-7kqrl3rv	598	22	response	response	NN
cord-347298-7kqrl3rv	598	23	to	to	IN
cord-347298-7kqrl3rv	598	24	infection	infection	NN
cord-347298-7kqrl3rv	598	25	(	(	-LRB-
cord-347298-7kqrl3rv	598	26	Takemura	Takemura	NNP
cord-347298-7kqrl3rv	598	27	and	and	CC
cord-347298-7kqrl3rv	598	28	Werb	Werb	NNP
cord-347298-7kqrl3rv	598	29	1984	1984	CD
cord-347298-7kqrl3rv	598	30	)	)	-RRB-
cord-347298-7kqrl3rv	598	31	.	.	.
cord-347298-7kqrl3rv	599	1	Significant	significant	JJ
cord-347298-7kqrl3rv	599	2	ROS	ROS	NNP
cord-347298-7kqrl3rv	599	3	include	include	VBP
cord-347298-7kqrl3rv	599	4	the	the	DT
cord-347298-7kqrl3rv	599	5	superoxide	superoxide	NN
cord-347298-7kqrl3rv	599	6	anion	anion	NN
cord-347298-7kqrl3rv	599	7	(	(	-LRB-
cord-347298-7kqrl3rv	599	8	O	o	UH
cord-347298-7kqrl3rv	599	9	2	2	CD
cord-347298-7kqrl3rv	599	10	-	-	,
cord-347298-7kqrl3rv	599	11	)	)	-RRB-
cord-347298-7kqrl3rv	599	12	,	,	,
cord-347298-7kqrl3rv	599	13	hydrogen	hydrogen	NN
cord-347298-7kqrl3rv	599	14	peroxide	peroxide	NN
cord-347298-7kqrl3rv	599	15	(	(	-LRB-
cord-347298-7kqrl3rv	599	16	H	h	NN
cord-347298-7kqrl3rv	599	17	2	2	CD
cord-347298-7kqrl3rv	599	18	O	o	NN
cord-347298-7kqrl3rv	599	19	2	2	CD
cord-347298-7kqrl3rv	599	20	)	)	-RRB-
cord-347298-7kqrl3rv	599	21	,	,	,
cord-347298-7kqrl3rv	599	22	the	the	DT
cord-347298-7kqrl3rv	599	23	hydroxyl	hydroxyl	NN
cord-347298-7kqrl3rv	599	24	radical	radical	JJ
cord-347298-7kqrl3rv	599	25	(	(	-LRB-
cord-347298-7kqrl3rv	599	26	HO	HO	NNP
cord-347298-7kqrl3rv	599	27	?	?	.
cord-347298-7kqrl3rv	599	28	)	)	-RRB-
cord-347298-7kqrl3rv	599	29	,	,	,
cord-347298-7kqrl3rv	599	30	nitric	nitric	NN
cord-347298-7kqrl3rv	599	31	oxide	oxide	NN
cord-347298-7kqrl3rv	599	32	(	(	-LRB-
cord-347298-7kqrl3rv	599	33	NO	no	UH
cord-347298-7kqrl3rv	599	34	?	?	.
cord-347298-7kqrl3rv	599	35	)	)	-RRB-
cord-347298-7kqrl3rv	599	36	,	,	,
cord-347298-7kqrl3rv	599	37	and	and	CC
cord-347298-7kqrl3rv	599	38	the	the	DT
cord-347298-7kqrl3rv	599	39	peroxynitrite	peroxynitrite	JJ
cord-347298-7kqrl3rv	599	40	anion	anion	NN
cord-347298-7kqrl3rv	599	41	(	(	-LRB-
cord-347298-7kqrl3rv	599	42	ONOO	ONOO	NNP
cord-347298-7kqrl3rv	599	43	À	à	NN
cord-347298-7kqrl3rv	599	44	)	)	-RRB-
cord-347298-7kqrl3rv	599	45	.	.	.
cord-347298-7kqrl3rv	600	1	Most	Most	JJS
cord-347298-7kqrl3rv	600	2	are	be	VBP
cord-347298-7kqrl3rv	600	3	products	product	NNS
cord-347298-7kqrl3rv	600	4	of	of	IN
cord-347298-7kqrl3rv	600	5	normal	normal	JJ
cord-347298-7kqrl3rv	600	6	cellular	cellular	JJ
cord-347298-7kqrl3rv	600	7	metabolism	metabolism	NN
cord-347298-7kqrl3rv	600	8	,	,	,
cord-347298-7kqrl3rv	600	9	but	but	CC
cord-347298-7kqrl3rv	600	10	their	-PRON-	PRP$
cord-347298-7kqrl3rv	600	11	production	production	NN
cord-347298-7kqrl3rv	600	12	is	be	VBZ
cord-347298-7kqrl3rv	600	13	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	600	14	during	during	IN
cord-347298-7kqrl3rv	600	15	inflammation	inflammation	NN
cord-347298-7kqrl3rv	600	16	through	through	IN
cord-347298-7kqrl3rv	600	17	the	the	DT
cord-347298-7kqrl3rv	600	18	activity	activity	NN
cord-347298-7kqrl3rv	600	19	of	of	IN
cord-347298-7kqrl3rv	600	20	the	the	DT
cord-347298-7kqrl3rv	600	21	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	600	22	NADPH	NADPH	NNP
cord-347298-7kqrl3rv	600	23	oxidase	oxidase	NN
cord-347298-7kqrl3rv	600	24	(	(	-LRB-
cord-347298-7kqrl3rv	600	25	nicotinamide	nicotinamide	NN
cord-347298-7kqrl3rv	600	26	adenine	adenine	NN
cord-347298-7kqrl3rv	600	27	dinucleotide	dinucleotide	NN
cord-347298-7kqrl3rv	600	28	phosphate	phosphate	NN
cord-347298-7kqrl3rv	600	29	-	-	HYPH
cord-347298-7kqrl3rv	600	30	oxidase	oxidase	NN
cord-347298-7kqrl3rv	600	31	)	)	-RRB-
cord-347298-7kqrl3rv	600	32	and	and	CC
cord-347298-7kqrl3rv	601	1	iNOS	inos	JJ
cord-347298-7kqrl3rv	601	2	(	(	-LRB-
cord-347298-7kqrl3rv	601	3	Forman	Forman	NNP
cord-347298-7kqrl3rv	601	4	and	and	CC
cord-347298-7kqrl3rv	601	5	Torres	Torres	NNP
cord-347298-7kqrl3rv	601	6	2002	2002	CD
cord-347298-7kqrl3rv	601	7	;	;	:
cord-347298-7kqrl3rv	601	8	Nathan	Nathan	NNP
cord-347298-7kqrl3rv	601	9	2006	2006	CD
cord-347298-7kqrl3rv	601	10	)	)	-RRB-
cord-347298-7kqrl3rv	601	11	.	.	.
cord-347298-7kqrl3rv	602	1	These	these	DT
cord-347298-7kqrl3rv	602	2	small	small	JJ
cord-347298-7kqrl3rv	602	3	molecules	molecule	NNS
cord-347298-7kqrl3rv	602	4	are	be	VBP
cord-347298-7kqrl3rv	602	5	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	602	6	to	to	IN
cord-347298-7kqrl3rv	602	7	many	many	JJ
cord-347298-7kqrl3rv	602	8	microorganisms	microorganism	NNS
cord-347298-7kqrl3rv	602	9	,	,	,
cord-347298-7kqrl3rv	602	10	although	although	IN
cord-347298-7kqrl3rv	602	11	some	some	DT
cord-347298-7kqrl3rv	602	12	play	play	VBP
cord-347298-7kqrl3rv	602	13	a	a	DT
cord-347298-7kqrl3rv	602	14	more	more	RBR
cord-347298-7kqrl3rv	602	15	complex	complex	JJ
cord-347298-7kqrl3rv	602	16	role	role	NN
cord-347298-7kqrl3rv	602	17	in	in	IN
cord-347298-7kqrl3rv	602	18	cell	cell	NN
cord-347298-7kqrl3rv	602	19	signaling	signaling	NN
cord-347298-7kqrl3rv	602	20	processes	process	NNS
cord-347298-7kqrl3rv	602	21	.	.	.
cord-347298-7kqrl3rv	603	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	603	2	also	also	RB
cord-347298-7kqrl3rv	603	3	interact	interact	VBP
cord-347298-7kqrl3rv	603	4	with	with	IN
cord-347298-7kqrl3rv	603	5	crucial	crucial	JJ
cord-347298-7kqrl3rv	603	6	intracellular	intracellular	JJ
cord-347298-7kqrl3rv	603	7	macromolecules	macromolecule	NNS
cord-347298-7kqrl3rv	603	8	,	,	,
cord-347298-7kqrl3rv	603	9	such	such	JJ
cord-347298-7kqrl3rv	603	10	as	as	IN
cord-347298-7kqrl3rv	603	11	proteins	protein	NNS
cord-347298-7kqrl3rv	603	12	,	,	,
cord-347298-7kqrl3rv	603	13	lipids	lipid	NNS
cord-347298-7kqrl3rv	603	14	,	,	,
cord-347298-7kqrl3rv	603	15	and	and	CC
cord-347298-7kqrl3rv	603	16	DNA	DNA	NNP
cord-347298-7kqrl3rv	603	17	,	,	,
cord-347298-7kqrl3rv	603	18	causing	cause	VBG
cord-347298-7kqrl3rv	603	19	oxidative	oxidative	JJ
cord-347298-7kqrl3rv	603	20	damage	damage	NN
cord-347298-7kqrl3rv	603	21	.	.	.
cord-347298-7kqrl3rv	604	1	Although	although	IN
cord-347298-7kqrl3rv	604	2	there	there	EX
cord-347298-7kqrl3rv	604	3	are	be	VBP
cord-347298-7kqrl3rv	604	4	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	604	5	repair	repair	NN
cord-347298-7kqrl3rv	604	6	systems	system	NNS
cord-347298-7kqrl3rv	604	7	to	to	TO
cord-347298-7kqrl3rv	604	8	correct	correct	VB
cord-347298-7kqrl3rv	604	9	oxidative	oxidative	JJ
cord-347298-7kqrl3rv	604	10	damage	damage	NN
cord-347298-7kqrl3rv	604	11	,	,	,
cord-347298-7kqrl3rv	604	12	excessive	excessive	JJ
cord-347298-7kqrl3rv	604	13	production	production	NN
cord-347298-7kqrl3rv	604	14	of	of	IN
cord-347298-7kqrl3rv	604	15	ROS	ROS	NNP
cord-347298-7kqrl3rv	604	16	contributes	contribute	VBZ
cord-347298-7kqrl3rv	604	17	to	to	IN
cord-347298-7kqrl3rv	604	18	the	the	DT
cord-347298-7kqrl3rv	604	19	pathology	pathology	NN
cord-347298-7kqrl3rv	604	20	of	of	IN
cord-347298-7kqrl3rv	604	21	many	many	JJ
cord-347298-7kqrl3rv	604	22	diseases	disease	NNS
cord-347298-7kqrl3rv	604	23	.	.	.
cord-347298-7kqrl3rv	605	1	Among	among	IN
cord-347298-7kqrl3rv	605	2	the	the	DT
cord-347298-7kqrl3rv	605	3	ROS	ROS	NNP
cord-347298-7kqrl3rv	605	4	,	,	,
cord-347298-7kqrl3rv	605	5	nitric	nitric	JJ
cord-347298-7kqrl3rv	605	6	oxide	oxide	NN
cord-347298-7kqrl3rv	605	7	represents	represent	VBZ
cord-347298-7kqrl3rv	605	8	a	a	DT
cord-347298-7kqrl3rv	605	9	special	special	JJ
cord-347298-7kqrl3rv	605	10	case	case	NN
cord-347298-7kqrl3rv	605	11	.	.	.
cord-347298-7kqrl3rv	606	1	At	at	IN
cord-347298-7kqrl3rv	606	2	high	high	JJ
cord-347298-7kqrl3rv	606	3	levels	level	NNS
cord-347298-7kqrl3rv	606	4	,	,	,
cord-347298-7kqrl3rv	606	5	NO	no	UH
cord-347298-7kqrl3rv	606	6	is	be	VBZ
cord-347298-7kqrl3rv	606	7	highly	highly	RB
cord-347298-7kqrl3rv	606	8	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	606	9	,	,	,
cord-347298-7kqrl3rv	606	10	especially	especially	RB
cord-347298-7kqrl3rv	606	11	as	as	IN
cord-347298-7kqrl3rv	606	12	a	a	DT
cord-347298-7kqrl3rv	606	13	precursor	precursor	NN
cord-347298-7kqrl3rv	606	14	of	of	IN
cord-347298-7kqrl3rv	606	15	the	the	DT
cord-347298-7kqrl3rv	606	16	peroxynitrite	peroxynitrite	JJ
cord-347298-7kqrl3rv	606	17	anion	anion	NN
cord-347298-7kqrl3rv	606	18	,	,	,
cord-347298-7kqrl3rv	606	19	but	but	CC
cord-347298-7kqrl3rv	606	20	at	at	IN
cord-347298-7kqrl3rv	606	21	low	low	JJ
cord-347298-7kqrl3rv	606	22	levels	level	NNS
cord-347298-7kqrl3rv	606	23	NO	no	DT
cord-347298-7kqrl3rv	606	24	acts	act	VBZ
cord-347298-7kqrl3rv	606	25	as	as	IN
cord-347298-7kqrl3rv	606	26	an	an	DT
cord-347298-7kqrl3rv	606	27	intracellular	intracellular	JJ
cord-347298-7kqrl3rv	606	28	and	and	CC
cord-347298-7kqrl3rv	606	29	extracellular	extracellular	JJ
cord-347298-7kqrl3rv	606	30	signaling	signal	VBG
cord-347298-7kqrl3rv	606	31	molecule	molecule	NN
cord-347298-7kqrl3rv	606	32	(	(	-LRB-
cord-347298-7kqrl3rv	606	33	Bogdan	Bogdan	NNP
cord-347298-7kqrl3rv	606	34	2001	2001	CD
cord-347298-7kqrl3rv	606	35	;	;	:
cord-347298-7kqrl3rv	606	36	Schmidt	Schmidt	NNP
cord-347298-7kqrl3rv	606	37	and	and	CC
cord-347298-7kqrl3rv	606	38	Walter	Walter	NNP
cord-347298-7kqrl3rv	606	39	1994	1994	CD
cord-347298-7kqrl3rv	606	40	)	)	-RRB-
cord-347298-7kqrl3rv	606	41	.	.	.
cord-347298-7kqrl3rv	607	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	607	2	is	be	VBZ
cord-347298-7kqrl3rv	607	3	produced	produce	VBN
cord-347298-7kqrl3rv	607	4	by	by	IN
cord-347298-7kqrl3rv	607	5	one	one	CD
cord-347298-7kqrl3rv	607	6	of	of	IN
cord-347298-7kqrl3rv	607	7	three	three	CD
cord-347298-7kqrl3rv	607	8	related	related	JJ
cord-347298-7kqrl3rv	607	9	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	607	10	,	,	,
cord-347298-7kqrl3rv	607	11	neuronal	neuronal	JJ
cord-347298-7kqrl3rv	607	12	NOS	NOS	NNP
cord-347298-7kqrl3rv	607	13	(	(	-LRB-
cord-347298-7kqrl3rv	607	14	nNOS	nnos	JJ
cord-347298-7kqrl3rv	607	15	or	or	CC
cord-347298-7kqrl3rv	607	16	NOS1	NOS1	NNP
cord-347298-7kqrl3rv	607	17	)	)	-RRB-
cord-347298-7kqrl3rv	607	18	,	,	,
cord-347298-7kqrl3rv	607	19	inducible	inducible	JJ
cord-347298-7kqrl3rv	607	20	NOS	NOS	NNP
cord-347298-7kqrl3rv	607	21	(	(	-LRB-
cord-347298-7kqrl3rv	607	22	iNOS	inos	NN
cord-347298-7kqrl3rv	607	23	or	or	CC
cord-347298-7kqrl3rv	607	24	NOS2	NOS2	NNP
cord-347298-7kqrl3rv	607	25	)	)	-RRB-
cord-347298-7kqrl3rv	607	26	,	,	,
cord-347298-7kqrl3rv	607	27	and	and	CC
cord-347298-7kqrl3rv	607	28	endothelial	endothelial	JJ
cord-347298-7kqrl3rv	607	29	NOS	NOS	NNP
cord-347298-7kqrl3rv	607	30	(	(	-LRB-
cord-347298-7kqrl3rv	607	31	eNOS	enos	JJ
cord-347298-7kqrl3rv	607	32	or	or	CC
cord-347298-7kqrl3rv	607	33	NOS3	NOS3	NNP
cord-347298-7kqrl3rv	607	34	)	)	-RRB-
cord-347298-7kqrl3rv	607	35	,	,	,
cord-347298-7kqrl3rv	607	36	which	which	WDT
cord-347298-7kqrl3rv	607	37	catalyze	catalyze	VBP
cord-347298-7kqrl3rv	607	38	the	the	DT
cord-347298-7kqrl3rv	607	39	conversion	conversion	NN
cord-347298-7kqrl3rv	607	40	of	of	IN
cord-347298-7kqrl3rv	607	41	L	l	NN
cord-347298-7kqrl3rv	607	42	-	-	HYPH
cord-347298-7kqrl3rv	607	43	arginine	arginine	NN
cord-347298-7kqrl3rv	607	44	to	to	IN
cord-347298-7kqrl3rv	607	45	L	l	NN
cord-347298-7kqrl3rv	607	46	-	-	HYPH
cord-347298-7kqrl3rv	607	47	citrulline	citrulline	NN
cord-347298-7kqrl3rv	607	48	and	and	CC
cord-347298-7kqrl3rv	607	49	NO	no	NN
cord-347298-7kqrl3rv	607	50	(	(	-LRB-
cord-347298-7kqrl3rv	607	51	Alderton	Alderton	NNP
cord-347298-7kqrl3rv	607	52	et	et	NNP
cord-347298-7kqrl3rv	607	53	al	al	NNP
cord-347298-7kqrl3rv	607	54	.	.	NNP
cord-347298-7kqrl3rv	607	55	2001	2001	CD
cord-347298-7kqrl3rv	607	56	)	)	-RRB-
cord-347298-7kqrl3rv	607	57	.	.	.
cord-347298-7kqrl3rv	608	1	The	the	DT
cord-347298-7kqrl3rv	608	2	NOS	NOS	NNP
cord-347298-7kqrl3rv	608	3	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	608	4	are	be	VBP
cord-347298-7kqrl3rv	608	5	homodimeric	homodimeric	JJ
cord-347298-7kqrl3rv	608	6	proteins	protein	NNS
cord-347298-7kqrl3rv	608	7	encoded	encode	VBN
cord-347298-7kqrl3rv	608	8	by	by	IN
cord-347298-7kqrl3rv	608	9	three	three	CD
cord-347298-7kqrl3rv	608	10	separate	separate	JJ
cord-347298-7kqrl3rv	608	11	genes	gene	NNS
cord-347298-7kqrl3rv	608	12	(	(	-LRB-
cord-347298-7kqrl3rv	608	13	Table	table	NN
cord-347298-7kqrl3rv	608	14	2	2	CD
cord-347298-7kqrl3rv	608	15	)	)	-RRB-
cord-347298-7kqrl3rv	608	16	.	.	.
cord-347298-7kqrl3rv	609	1	Both	both	DT
cord-347298-7kqrl3rv	609	2	nNOS	nnos	JJ
cord-347298-7kqrl3rv	609	3	and	and	CC
cord-347298-7kqrl3rv	609	4	eNOS	eNOS	NNP
cord-347298-7kqrl3rv	609	5	are	be	VBP
cord-347298-7kqrl3rv	609	6	constitutively	constitutively	RB
cord-347298-7kqrl3rv	609	7	expressed	express	VBN
cord-347298-7kqrl3rv	609	8	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	609	9	whose	whose	WP$
cord-347298-7kqrl3rv	609	10	activity	activity	NN
cord-347298-7kqrl3rv	609	11	is	be	VBZ
cord-347298-7kqrl3rv	609	12	regulated	regulate	VBN
cord-347298-7kqrl3rv	609	13	through	through	IN
cord-347298-7kqrl3rv	609	14	a	a	DT
cord-347298-7kqrl3rv	609	15	calcium	calcium	NN
cord-347298-7kqrl3rv	609	16	-	-	HYPH
cord-347298-7kqrl3rv	609	17	calmodulin	calmodulin	NN
cord-347298-7kqrl3rv	609	18	-	-	HYPH
cord-347298-7kqrl3rv	609	19	mediated	mediate	VBN
cord-347298-7kqrl3rv	609	20	mechanism	mechanism	NN
cord-347298-7kqrl3rv	609	21	,	,	,
cord-347298-7kqrl3rv	609	22	whereas	whereas	IN
cord-347298-7kqrl3rv	609	23	iNOS	inos	NN
cord-347298-7kqrl3rv	609	24	is	be	VBZ
cord-347298-7kqrl3rv	609	25	a	a	DT
cord-347298-7kqrl3rv	609	26	constitutively	constitutively	RB
cord-347298-7kqrl3rv	609	27	activated	activate	VBN
cord-347298-7kqrl3rv	609	28	enzyme	enzyme	NN
cord-347298-7kqrl3rv	609	29	that	that	WDT
cord-347298-7kqrl3rv	609	30	is	be	VBZ
cord-347298-7kqrl3rv	609	31	regulated	regulate	VBN
cord-347298-7kqrl3rv	609	32	at	at	IN
cord-347298-7kqrl3rv	609	33	the	the	DT
cord-347298-7kqrl3rv	609	34	transcriptional	transcriptional	JJ
cord-347298-7kqrl3rv	609	35	and	and	CC
cord-347298-7kqrl3rv	609	36	translational	translational	JJ
cord-347298-7kqrl3rv	609	37	levels	level	NNS
cord-347298-7kqrl3rv	609	38	by	by	IN
cord-347298-7kqrl3rv	609	39	various	various	JJ
cord-347298-7kqrl3rv	609	40	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	609	41	mediators	mediator	NNS
cord-347298-7kqrl3rv	609	42	,	,	,
cord-347298-7kqrl3rv	609	43	including	include	VBG
cord-347298-7kqrl3rv	609	44	LPS	LPS	NNP
cord-347298-7kqrl3rv	609	45	,	,	,
cord-347298-7kqrl3rv	609	46	IL1	IL1	NNP
cord-347298-7kqrl3rv	609	47	,	,	,
cord-347298-7kqrl3rv	609	48	and	and	CC
cord-347298-7kqrl3rv	609	49	TNF	TNF	NNP
cord-347298-7kqrl3rv	609	50	(	(	-LRB-
cord-347298-7kqrl3rv	609	51	Wolkow	Wolkow	NNP
cord-347298-7kqrl3rv	609	52	1998	1998	CD
cord-347298-7kqrl3rv	609	53	)	)	-RRB-
cord-347298-7kqrl3rv	609	54	.	.	.
cord-347298-7kqrl3rv	610	1	In	in	IN
cord-347298-7kqrl3rv	610	2	studies	study	NNS
cord-347298-7kqrl3rv	610	3	in	in	IN
cord-347298-7kqrl3rv	610	4	various	various	JJ
cord-347298-7kqrl3rv	610	5	species	specie	NNS
cord-347298-7kqrl3rv	610	6	,	,	,
cord-347298-7kqrl3rv	610	7	NOS	NOS	NNP
cord-347298-7kqrl3rv	610	8	has	have	VBZ
cord-347298-7kqrl3rv	610	9	been	be	VBN
cord-347298-7kqrl3rv	610	10	found	find	VBN
cord-347298-7kqrl3rv	610	11	in	in	IN
cord-347298-7kqrl3rv	610	12	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	610	13	cells	cell	NNS
cord-347298-7kqrl3rv	610	14	,	,	,
cord-347298-7kqrl3rv	610	15	Leydig	leydig	NN
cord-347298-7kqrl3rv	610	16	cells	cell	NNS
cord-347298-7kqrl3rv	610	17	,	,	,
cord-347298-7kqrl3rv	610	18	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	610	19	cells	cell	NNS
cord-347298-7kqrl3rv	610	20	,	,	,
cord-347298-7kqrl3rv	610	21	germ	germ	NN
cord-347298-7kqrl3rv	610	22	cells	cell	NNS
cord-347298-7kqrl3rv	610	23	,	,	,
cord-347298-7kqrl3rv	610	24	testicular	testicular	JJ
cord-347298-7kqrl3rv	610	25	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	610	26	,	,	,
cord-347298-7kqrl3rv	610	27	and	and	CC
cord-347298-7kqrl3rv	610	28	vascular	vascular	JJ
cord-347298-7kqrl3rv	610	29	endothelial	endothelial	JJ
cord-347298-7kqrl3rv	610	30	cells	cell	NNS
cord-347298-7kqrl3rv	610	31	(	(	-LRB-
cord-347298-7kqrl3rv	610	32	Kim	Kim	NNP
cord-347298-7kqrl3rv	610	33	et	et	NNP
cord-347298-7kqrl3rv	610	34	al	al	NNP
cord-347298-7kqrl3rv	610	35	.	.	NNP
cord-347298-7kqrl3rv	610	36	2007	2007	CD
cord-347298-7kqrl3rv	610	37	;	;	:
cord-347298-7kqrl3rv	610	38	Lee	Lee	NNP
cord-347298-7kqrl3rv	610	39	and	and	CC
cord-347298-7kqrl3rv	610	40	Cheng	Cheng	NNP
cord-347298-7kqrl3rv	610	41	2004	2004	CD
cord-347298-7kqrl3rv	610	42	)	)	-RRB-
cord-347298-7kqrl3rv	610	43	.	.	.
cord-347298-7kqrl3rv	611	1	The	the	DT
cord-347298-7kqrl3rv	611	2	nNOS	nnos	JJ
cord-347298-7kqrl3rv	611	3	gene	gene	NN
cord-347298-7kqrl3rv	611	4	also	also	RB
cord-347298-7kqrl3rv	611	5	produces	produce	VBZ
cord-347298-7kqrl3rv	611	6	a	a	DT
cord-347298-7kqrl3rv	611	7	testis	testis	NN
cord-347298-7kqrl3rv	611	8	-	-	HYPH
cord-347298-7kqrl3rv	611	9	specific	specific	JJ
cord-347298-7kqrl3rv	611	10	isoform	isoform	NN
cord-347298-7kqrl3rv	611	11	,	,	,
cord-347298-7kqrl3rv	611	12	TnNOS	TnNOS	NNP
cord-347298-7kqrl3rv	611	13	,	,	,
cord-347298-7kqrl3rv	611	14	which	which	WDT
cord-347298-7kqrl3rv	611	15	has	have	VBZ
cord-347298-7kqrl3rv	611	16	been	be	VBN
cord-347298-7kqrl3rv	611	17	localized	localize	VBN
cord-347298-7kqrl3rv	611	18	to	to	IN
cord-347298-7kqrl3rv	611	19	Leydig	leydig	NN
cord-347298-7kqrl3rv	611	20	cells	cell	NNS
cord-347298-7kqrl3rv	611	21	(	(	-LRB-
cord-347298-7kqrl3rv	611	22	Wang	Wang	NNP
cord-347298-7kqrl3rv	611	23	et	et	NNP
cord-347298-7kqrl3rv	611	24	al	al	NNP
cord-347298-7kqrl3rv	611	25	.	.	.
cord-347298-7kqrl3rv	611	26	1997	1997	CD
cord-347298-7kqrl3rv	611	27	)	)	-RRB-
cord-347298-7kqrl3rv	611	28	.	.	.
cord-347298-7kqrl3rv	612	1	In	in	IN
cord-347298-7kqrl3rv	612	2	the	the	DT
cord-347298-7kqrl3rv	612	3	normal	normal	JJ
cord-347298-7kqrl3rv	612	4	rat	rat	NN
cord-347298-7kqrl3rv	612	5	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	612	6	epithelium	epithelium	NN
cord-347298-7kqrl3rv	612	7	,	,	,
cord-347298-7kqrl3rv	612	8	iNOS	iNOS	NNP
cord-347298-7kqrl3rv	612	9	is	be	VBZ
cord-347298-7kqrl3rv	612	10	expressed	express	VBN
cord-347298-7kqrl3rv	612	11	by	by	IN
cord-347298-7kqrl3rv	612	12	elongating	elongate	VBG
cord-347298-7kqrl3rv	612	13	spermatids	spermatids	NNP
cord-347298-7kqrl3rv	612	14	and	and	CC
cord-347298-7kqrl3rv	612	15	pachytene	pachytene	NNP
cord-347298-7kqrl3rv	612	16	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	612	17	,	,	,
cord-347298-7kqrl3rv	612	18	particularly	particularly	RB
cord-347298-7kqrl3rv	612	19	during	during	IN
cord-347298-7kqrl3rv	612	20	the	the	DT
cord-347298-7kqrl3rv	612	21	stages	stage	NNS
cord-347298-7kqrl3rv	612	22	immediately	immediately	RB
cord-347298-7kqrl3rv	612	23	following	follow	VBG
cord-347298-7kqrl3rv	612	24	sperm	sperm	NN
cord-347298-7kqrl3rv	612	25	release	release	NN
cord-347298-7kqrl3rv	612	26	,	,	,
cord-347298-7kqrl3rv	612	27	with	with	IN
cord-347298-7kqrl3rv	612	28	relatively	relatively	RB
cord-347298-7kqrl3rv	612	29	lower	low	JJR
cord-347298-7kqrl3rv	612	30	levels	level	NNS
cord-347298-7kqrl3rv	612	31	of	of	IN
cord-347298-7kqrl3rv	612	32	expression	expression	NN
cord-347298-7kqrl3rv	612	33	in	in	IN
cord-347298-7kqrl3rv	612	34	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	612	35	cells	cell	NNS
cord-347298-7kqrl3rv	612	36	and	and	CC
cord-347298-7kqrl3rv	612	37	peritubular	peritubular	JJ
cord-347298-7kqrl3rv	612	38	cells	cell	NNS
cord-347298-7kqrl3rv	612	39	throughout	throughout	IN
cord-347298-7kqrl3rv	612	40	the	the	DT
cord-347298-7kqrl3rv	612	41	(	(	-LRB-
cord-347298-7kqrl3rv	612	42	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	612	43	et	et	NNP
cord-347298-7kqrl3rv	612	44	al	al	NNP
cord-347298-7kqrl3rv	612	45	.	.	NNP
cord-347298-7kqrl3rv	612	46	2000a	2000a	CD
cord-347298-7kqrl3rv	612	47	)	)	-RRB-
cord-347298-7kqrl3rv	612	48	.	.	.
cord-347298-7kqrl3rv	613	1	In	in	IN
cord-347298-7kqrl3rv	613	2	the	the	DT
cord-347298-7kqrl3rv	613	3	interstitium	interstitium	NN
cord-347298-7kqrl3rv	613	4	,	,	,
cord-347298-7kqrl3rv	613	5	macrophage	macrophage	NN
cord-347298-7kqrl3rv	613	6	expression	expression	NN
cord-347298-7kqrl3rv	613	7	of	of	IN
cord-347298-7kqrl3rv	613	8	iNOS	inos	NN
cord-347298-7kqrl3rv	613	9	appears	appear	VBZ
cord-347298-7kqrl3rv	613	10	to	to	TO
cord-347298-7kqrl3rv	613	11	be	be	VB
cord-347298-7kqrl3rv	613	12	largely	largely	RB
cord-347298-7kqrl3rv	613	13	confined	confine	VBN
cord-347298-7kqrl3rv	613	14	to	to	IN
cord-347298-7kqrl3rv	613	15	the	the	DT
cord-347298-7kqrl3rv	613	16	minority	minority	NN
cord-347298-7kqrl3rv	613	17	of	of	IN
cord-347298-7kqrl3rv	613	18	CD163-negative	cd163-negative	JJ
cord-347298-7kqrl3rv	613	19	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	613	20	of	of	IN
cord-347298-7kqrl3rv	613	21	the	the	DT
cord-347298-7kqrl3rv	613	22	testis	testis	NN
cord-347298-7kqrl3rv	613	23	,	,	,
cord-347298-7kqrl3rv	613	24	and	and	CC
cord-347298-7kqrl3rv	613	25	is	be	VBZ
cord-347298-7kqrl3rv	613	26	not	not	RB
cord-347298-7kqrl3rv	613	27	detectable	detectable	JJ
cord-347298-7kqrl3rv	613	28	in	in	IN
cord-347298-7kqrl3rv	613	29	the	the	DT
cord-347298-7kqrl3rv	613	30	majority	majority	NN
cord-347298-7kqrl3rv	613	31	of	of	IN
cord-347298-7kqrl3rv	613	32	resident	resident	JJ
cord-347298-7kqrl3rv	613	33	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	613	34	even	even	RB
cord-347298-7kqrl3rv	613	35	during	during	IN
cord-347298-7kqrl3rv	613	36	inflammation	inflammation	NN
cord-347298-7kqrl3rv	613	37	(	(	-LRB-
cord-347298-7kqrl3rv	613	38	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	613	39	et	et	NNP
cord-347298-7kqrl3rv	613	40	al	al	NNP
cord-347298-7kqrl3rv	613	41	.	.	NNP
cord-347298-7kqrl3rv	613	42	2000a	2000a	CD
cord-347298-7kqrl3rv	613	43	;	;	:
cord-347298-7kqrl3rv	613	44	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	613	45	et	et	NNP
cord-347298-7kqrl3rv	613	46	al	al	NNP
cord-347298-7kqrl3rv	613	47	.	.	NNP
cord-347298-7kqrl3rv	613	48	2002a	2002a	CD
cord-347298-7kqrl3rv	613	49	)	)	-RRB-
cord-347298-7kqrl3rv	613	50	.	.	.
cord-347298-7kqrl3rv	614	1	Testicular	testicular	JJ
cord-347298-7kqrl3rv	614	2	cell	cell	NN
cord-347298-7kqrl3rv	614	3	iNOS	inos	JJ
cord-347298-7kqrl3rv	614	4	expression	expression	NN
cord-347298-7kqrl3rv	614	5	and	and	CC
cord-347298-7kqrl3rv	614	6	NO	no	DT
cord-347298-7kqrl3rv	614	7	production	production	NN
cord-347298-7kqrl3rv	614	8	are	be	VBP
cord-347298-7kqrl3rv	614	9	increased	increase	VBN
cord-347298-7kqrl3rv	614	10	by	by	IN
cord-347298-7kqrl3rv	614	11	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	614	12	events	event	NNS
cord-347298-7kqrl3rv	614	13	induced	induce	VBN
cord-347298-7kqrl3rv	614	14	by	by	IN
cord-347298-7kqrl3rv	614	15	LPS	LPS	NNP
cord-347298-7kqrl3rv	614	16	,	,	,
cord-347298-7kqrl3rv	614	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	614	18	torsion	torsion	NN
cord-347298-7kqrl3rv	614	19	,	,	,
cord-347298-7kqrl3rv	614	20	or	or	CC
cord-347298-7kqrl3rv	614	21	testicular	testicular	JJ
cord-347298-7kqrl3rv	614	22	heating	heating	NN
cord-347298-7kqrl3rv	615	1	(	(	-LRB-
cord-347298-7kqrl3rv	615	2	Lue	Lue	NNP
cord-347298-7kqrl3rv	615	3	et	et	NNP
cord-347298-7kqrl3rv	615	4	al	al	NNP
cord-347298-7kqrl3rv	615	5	.	.	.
cord-347298-7kqrl3rv	616	1	2003	2003	CD
cord-347298-7kqrl3rv	616	2	;	;	:
cord-347298-7kqrl3rv	616	3	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	616	4	et	et	NNP
cord-347298-7kqrl3rv	616	5	al	al	NNP
cord-347298-7kqrl3rv	616	6	.	.	.
cord-347298-7kqrl3rv	617	1	2000a	2000a	CD
cord-347298-7kqrl3rv	617	2	;	;	:
cord-347298-7kqrl3rv	617	3	Shiraishi	Shiraishi	NNP
cord-347298-7kqrl3rv	617	4	et	et	NNP
cord-347298-7kqrl3rv	617	5	al	al	NNP
cord-347298-7kqrl3rv	617	6	.	.	NNP
cord-347298-7kqrl3rv	617	7	2001	2001	CD
cord-347298-7kqrl3rv	617	8	)	)	-RRB-
cord-347298-7kqrl3rv	617	9	.	.	.
cord-347298-7kqrl3rv	618	1	Production	production	NN
cord-347298-7kqrl3rv	618	2	of	of	IN
cord-347298-7kqrl3rv	618	3	NO	no	DT
cord-347298-7kqrl3rv	618	4	by	by	IN
cord-347298-7kqrl3rv	618	5	germ	germ	NN
cord-347298-7kqrl3rv	618	6	cells	cell	NNS
cord-347298-7kqrl3rv	618	7	,	,	,
cord-347298-7kqrl3rv	618	8	in	in	IN
cord-347298-7kqrl3rv	618	9	particular	particular	JJ
cord-347298-7kqrl3rv	618	10	,	,	,
cord-347298-7kqrl3rv	618	11	is	be	VBZ
cord-347298-7kqrl3rv	618	12	implicated	implicate	VBN
cord-347298-7kqrl3rv	618	13	in	in	IN
cord-347298-7kqrl3rv	618	14	the	the	DT
cord-347298-7kqrl3rv	618	15	control	control	NN
cord-347298-7kqrl3rv	618	16	of	of	IN
cord-347298-7kqrl3rv	618	17	the	the	DT
cord-347298-7kqrl3rv	618	18	formation	formation	NN
cord-347298-7kqrl3rv	618	19	and	and	CC
cord-347298-7kqrl3rv	618	20	disassembly	disassembly	NN
cord-347298-7kqrl3rv	618	21	of	of	IN
cord-347298-7kqrl3rv	618	22	the	the	DT
cord-347298-7kqrl3rv	618	23	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	618	24	cell	cell	NN
cord-347298-7kqrl3rv	618	25	junctions	junction	NNS
cord-347298-7kqrl3rv	618	26	that	that	WDT
cord-347298-7kqrl3rv	618	27	constitute	constitute	VBP
cord-347298-7kqrl3rv	618	28	the	the	DT
cord-347298-7kqrl3rv	618	29	blood	blood	NN
cord-347298-7kqrl3rv	618	30	-	-	HYPH
cord-347298-7kqrl3rv	618	31	testis	testis	NN
cord-347298-7kqrl3rv	618	32	barrier	barrier	NN
cord-347298-7kqrl3rv	618	33	,	,	,
cord-347298-7kqrl3rv	618	34	as	as	RB
cord-347298-7kqrl3rv	618	35	well	well	RB
cord-347298-7kqrl3rv	618	36	as	as	IN
cord-347298-7kqrl3rv	618	37	the	the	DT
cord-347298-7kqrl3rv	618	38	junctional	junctional	JJ
cord-347298-7kqrl3rv	618	39	complexes	complex	NNS
cord-347298-7kqrl3rv	618	40	involved	involve	VBN
cord-347298-7kqrl3rv	618	41	in	in	IN
cord-347298-7kqrl3rv	618	42	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	618	43	-	-	HYPH
cord-347298-7kqrl3rv	618	44	germ	germ	NN
cord-347298-7kqrl3rv	618	45	cell	cell	NN
cord-347298-7kqrl3rv	618	46	adhesion	adhesion	NN
cord-347298-7kqrl3rv	618	47	Lee	Lee	NNP
cord-347298-7kqrl3rv	618	48	et	et	NNP
cord-347298-7kqrl3rv	618	49	al	al	NNP
cord-347298-7kqrl3rv	618	50	.	.	NNP
cord-347298-7kqrl3rv	618	51	2005	2005	CD
cord-347298-7kqrl3rv	618	52	)	)	-RRB-
cord-347298-7kqrl3rv	618	53	.	.	.
cord-347298-7kqrl3rv	619	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	619	2	,	,	,
cord-347298-7kqrl3rv	619	3	pachytene	pachytene	NN
cord-347298-7kqrl3rv	619	4	and	and	CC
cord-347298-7kqrl3rv	619	5	round	round	JJ
cord-347298-7kqrl3rv	619	6	spermatid	spermatid	JJ
cord-347298-7kqrl3rv	619	7	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	619	8	is	be	VBZ
cord-347298-7kqrl3rv	619	9	significantly	significantly	RB
cord-347298-7kqrl3rv	619	10	reduced	reduce	VBN
cord-347298-7kqrl3rv	619	11	in	in	IN
cord-347298-7kqrl3rv	619	12	iNOS	inos	JJ
cord-347298-7kqrl3rv	619	13	null	null	JJ
cord-347298-7kqrl3rv	619	14	mice	mouse	NNS
cord-347298-7kqrl3rv	619	15	,	,	,
cord-347298-7kqrl3rv	619	16	leading	lead	VBG
cord-347298-7kqrl3rv	619	17	to	to	IN
cord-347298-7kqrl3rv	619	18	an	an	DT
cord-347298-7kqrl3rv	619	19	increase	increase	NN
cord-347298-7kqrl3rv	619	20	in	in	IN
cord-347298-7kqrl3rv	619	21	daily	daily	JJ
cord-347298-7kqrl3rv	619	22	sperm	sperm	NN
cord-347298-7kqrl3rv	619	23	output	output	NN
cord-347298-7kqrl3rv	619	24	and	and	CC
cord-347298-7kqrl3rv	619	25	indicating	indicate	VBG
cord-347298-7kqrl3rv	619	26	a	a	DT
cord-347298-7kqrl3rv	619	27	key	key	JJ
cord-347298-7kqrl3rv	619	28	role	role	NN
cord-347298-7kqrl3rv	619	29	for	for	IN
cord-347298-7kqrl3rv	619	30	iNOS	inos	NN
cord-347298-7kqrl3rv	619	31	in	in	IN
cord-347298-7kqrl3rv	619	32	limiting	limit	VBG
cord-347298-7kqrl3rv	619	33	germ	germ	NN
cord-347298-7kqrl3rv	619	34	cell	cell	NN
cord-347298-7kqrl3rv	619	35	survival	survival	NN
cord-347298-7kqrl3rv	619	36	and/or	and/or	CC
cord-347298-7kqrl3rv	619	37	the	the	DT
cord-347298-7kqrl3rv	619	38	carrying	carrying	NN
cord-347298-7kqrl3rv	619	39	capacity	capacity	NN
cord-347298-7kqrl3rv	619	40	of	of	IN
cord-347298-7kqrl3rv	619	41	the	the	DT
cord-347298-7kqrl3rv	619	42	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	619	43	cells	cell	NNS
cord-347298-7kqrl3rv	619	44	(	(	-LRB-
cord-347298-7kqrl3rv	619	45	Lue	Lue	NNP
cord-347298-7kqrl3rv	619	46	et	et	NNP
cord-347298-7kqrl3rv	619	47	al	al	NNP
cord-347298-7kqrl3rv	619	48	.	.	NNP
cord-347298-7kqrl3rv	619	49	2003	2003	CD
cord-347298-7kqrl3rv	619	50	)	)	-RRB-
cord-347298-7kqrl3rv	619	51	.	.	.
cord-347298-7kqrl3rv	620	1	NO	no	DT
cord-347298-7kqrl3rv	620	2	inhibits	inhibit	VBZ
cord-347298-7kqrl3rv	620	3	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	620	4	cell	cell	NN
cord-347298-7kqrl3rv	620	5	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	620	6	directly	directly	RB
cord-347298-7kqrl3rv	620	7	,	,	,
cord-347298-7kqrl3rv	620	8	an	an	DT
cord-347298-7kqrl3rv	620	9	action	action	NN
cord-347298-7kqrl3rv	620	10	that	that	WDT
cord-347298-7kqrl3rv	620	11	is	be	VBZ
cord-347298-7kqrl3rv	620	12	probably	probably	RB
cord-347298-7kqrl3rv	620	13	mediated	mediate	VBN
cord-347298-7kqrl3rv	620	14	through	through	IN
cord-347298-7kqrl3rv	620	15	oxidative	oxidative	JJ
cord-347298-7kqrl3rv	620	16	damage	damage	NN
cord-347298-7kqrl3rv	620	17	,	,	,
cord-347298-7kqrl3rv	620	18	and	and	CC
cord-347298-7kqrl3rv	620	19	treatment	treatment	NN
cord-347298-7kqrl3rv	620	20	with	with	IN
cord-347298-7kqrl3rv	620	21	NOS	NOS	NNP
cord-347298-7kqrl3rv	620	22	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	620	23	counteracts	counteract	VBZ
cord-347298-7kqrl3rv	620	24	the	the	DT
cord-347298-7kqrl3rv	620	25	normal	normal	JJ
cord-347298-7kqrl3rv	620	26	decrease	decrease	NN
cord-347298-7kqrl3rv	620	27	in	in	IN
cord-347298-7kqrl3rv	620	28	testosterone	testosterone	NN
cord-347298-7kqrl3rv	620	29	associated	associate	VBN
cord-347298-7kqrl3rv	620	30	with	with	IN
cord-347298-7kqrl3rv	620	31	sepsis	sepsis	NN
cord-347298-7kqrl3rv	620	32	or	or	CC
cord-347298-7kqrl3rv	620	33	stress	stress	NN
cord-347298-7kqrl3rv	620	34	(	(	-LRB-
cord-347298-7kqrl3rv	620	35	Del	Del	NNP
cord-347298-7kqrl3rv	620	36	Punta	Punta	NNP
cord-347298-7kqrl3rv	620	37	et	et	NNP
cord-347298-7kqrl3rv	620	38	al	al	NNP
cord-347298-7kqrl3rv	620	39	.	.	.
cord-347298-7kqrl3rv	621	1	1996	1996	CD
cord-347298-7kqrl3rv	621	2	;	;	:
cord-347298-7kqrl3rv	621	3	Sharma	Sharma	NNP
cord-347298-7kqrl3rv	621	4	et	et	NNP
cord-347298-7kqrl3rv	621	5	al	al	NNP
cord-347298-7kqrl3rv	621	6	.	.	.
cord-347298-7kqrl3rv	622	1	1998	1998	CD
cord-347298-7kqrl3rv	622	2	;	;	:
cord-347298-7kqrl3rv	622	3	Welch	Welch	NNP
cord-347298-7kqrl3rv	622	4	et	et	NNP
cord-347298-7kqrl3rv	622	5	al	al	NNP
cord-347298-7kqrl3rv	622	6	.	.	NNP
cord-347298-7kqrl3rv	622	7	1995	1995	CD
cord-347298-7kqrl3rv	622	8	)	)	-RRB-
cord-347298-7kqrl3rv	622	9	.	.	.
cord-347298-7kqrl3rv	623	1	Similarly	similarly	RB
cord-347298-7kqrl3rv	623	2	,	,	,
cord-347298-7kqrl3rv	623	3	production	production	NN
cord-347298-7kqrl3rv	623	4	of	of	IN
cord-347298-7kqrl3rv	623	5	other	other	JJ
cord-347298-7kqrl3rv	623	6	ROS	ROS	NNP
cord-347298-7kqrl3rv	623	7	has	have	VBZ
cord-347298-7kqrl3rv	623	8	been	be	VBN
cord-347298-7kqrl3rv	623	9	implicated	implicate	VBN
cord-347298-7kqrl3rv	623	10	in	in	IN
cord-347298-7kqrl3rv	623	11	the	the	DT
cord-347298-7kqrl3rv	623	12	loss	loss	NN
cord-347298-7kqrl3rv	623	13	of	of	IN
cord-347298-7kqrl3rv	623	14	steroidogenic	steroidogenic	JJ
cord-347298-7kqrl3rv	623	15	function	function	NN
cord-347298-7kqrl3rv	623	16	in	in	IN
cord-347298-7kqrl3rv	623	17	various	various	JJ
cord-347298-7kqrl3rv	623	18	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	623	19	models	model	NNS
cord-347298-7kqrl3rv	623	20	and	and	CC
cord-347298-7kqrl3rv	623	21	in	in	IN
cord-347298-7kqrl3rv	623	22	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	623	23	cell	cell	NN
cord-347298-7kqrl3rv	623	24	cultures	culture	NNS
cord-347298-7kqrl3rv	623	25	(	(	-LRB-
cord-347298-7kqrl3rv	623	26	Georgiou	Georgiou	NNP
cord-347298-7kqrl3rv	623	27	et	et	FW
cord-347298-7kqrl3rv	623	28	al	al	NNP
cord-347298-7kqrl3rv	623	29	.	.	NNP
cord-347298-7kqrl3rv	623	30	1987	1987	CD
cord-347298-7kqrl3rv	623	31	;	;	.
cord-347298-7kqrl3rv	624	1	Quinn	Quinn	NNP
cord-347298-7kqrl3rv	624	2	and	and	CC
cord-347298-7kqrl3rv	624	3	Payne	Payne	NNP
cord-347298-7kqrl3rv	624	4	1984	1984	CD
cord-347298-7kqrl3rv	624	5	)	)	-RRB-
cord-347298-7kqrl3rv	624	6	.	.	.
cord-347298-7kqrl3rv	625	1	Last	last	JJ
cord-347298-7kqrl3rv	625	2	but	but	CC
cord-347298-7kqrl3rv	625	3	not	not	RB
cord-347298-7kqrl3rv	625	4	least	least	JJS
cord-347298-7kqrl3rv	625	5	,	,	,
cord-347298-7kqrl3rv	625	6	NO	no	UH
cord-347298-7kqrl3rv	625	7	is	be	VBZ
cord-347298-7kqrl3rv	625	8	a	a	DT
cord-347298-7kqrl3rv	625	9	potent	potent	JJ
cord-347298-7kqrl3rv	625	10	vasodilator	vasodilator	NN
cord-347298-7kqrl3rv	625	11	,	,	,
cord-347298-7kqrl3rv	625	12	and	and	CC
cord-347298-7kqrl3rv	625	13	plays	play	VBZ
cord-347298-7kqrl3rv	625	14	a	a	DT
cord-347298-7kqrl3rv	625	15	role	role	NN
cord-347298-7kqrl3rv	625	16	in	in	IN
cord-347298-7kqrl3rv	625	17	the	the	DT
cord-347298-7kqrl3rv	625	18	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	625	19	control	control	NN
cord-347298-7kqrl3rv	625	20	of	of	IN
cord-347298-7kqrl3rv	625	21	testicular	testicular	JJ
cord-347298-7kqrl3rv	625	22	blood	blood	NN
cord-347298-7kqrl3rv	625	23	flow	flow	NN
cord-347298-7kqrl3rv	625	24	and	and	CC
cord-347298-7kqrl3rv	625	25	formation	formation	NN
cord-347298-7kqrl3rv	625	26	of	of	IN
cord-347298-7kqrl3rv	625	27	the	the	DT
cord-347298-7kqrl3rv	625	28	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	625	29	fluid	fluid	NN
cord-347298-7kqrl3rv	625	30	(	(	-LRB-
cord-347298-7kqrl3rv	625	31	Lissbrant	Lissbrant	NNP
cord-347298-7kqrl3rv	625	32	et	et	FW
cord-347298-7kqrl3rv	625	33	al	al	NNP
cord-347298-7kqrl3rv	625	34	.	.	.
cord-347298-7kqrl3rv	625	35	1997	1997	CD
cord-347298-7kqrl3rv	625	36	;	;	.
cord-347298-7kqrl3rv	626	1	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	626	2	et	et	NNP
cord-347298-7kqrl3rv	626	3	al	al	NNP
cord-347298-7kqrl3rv	626	4	.	.	NNP
cord-347298-7kqrl3rv	626	5	2000a	2000a	CD
cord-347298-7kqrl3rv	626	6	)	)	-RRB-
cord-347298-7kqrl3rv	626	7	.	.	.
cord-347298-7kqrl3rv	627	1	Production	production	NN
cord-347298-7kqrl3rv	627	2	of	of	IN
cord-347298-7kqrl3rv	627	3	NO	no	DT
cord-347298-7kqrl3rv	627	4	is	be	VBZ
cord-347298-7kqrl3rv	627	5	an	an	DT
cord-347298-7kqrl3rv	627	6	important	important	JJ
cord-347298-7kqrl3rv	627	7	mediator	mediator	NN
cord-347298-7kqrl3rv	627	8	of	of	IN
cord-347298-7kqrl3rv	627	9	germ	germ	NN
cord-347298-7kqrl3rv	627	10	cell	cell	NN
cord-347298-7kqrl3rv	627	11	death	death	NN
cord-347298-7kqrl3rv	627	12	in	in	IN
cord-347298-7kqrl3rv	627	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	627	14	torsion	torsion	NN
cord-347298-7kqrl3rv	628	1	(	(	-LRB-
cord-347298-7kqrl3rv	628	2	Moon	Moon	NNP
cord-347298-7kqrl3rv	628	3	et	et	NNP
cord-347298-7kqrl3rv	628	4	al	al	NNP
cord-347298-7kqrl3rv	628	5	.	.	.
cord-347298-7kqrl3rv	628	6	2005	2005	CD
cord-347298-7kqrl3rv	629	1	;	;	:
cord-347298-7kqrl3rv	629	2	Shiraishi	Shiraishi	NNP
cord-347298-7kqrl3rv	629	3	et	et	NNP
cord-347298-7kqrl3rv	629	4	al	al	NNP
cord-347298-7kqrl3rv	629	5	.	.	NNP
cord-347298-7kqrl3rv	629	6	2001	2001	CD
cord-347298-7kqrl3rv	629	7	)	)	-RRB-
cord-347298-7kqrl3rv	629	8	,	,	,
cord-347298-7kqrl3rv	629	9	and	and	CC
cord-347298-7kqrl3rv	629	10	may	may	MD
cord-347298-7kqrl3rv	629	11	be	be	VB
cord-347298-7kqrl3rv	629	12	involved	involve	VBN
cord-347298-7kqrl3rv	629	13	in	in	IN
cord-347298-7kqrl3rv	629	14	the	the	DT
cord-347298-7kqrl3rv	629	15	testicular	testicular	JJ
cord-347298-7kqrl3rv	629	16	damage	damage	NN
cord-347298-7kqrl3rv	629	17	associated	associate	VBN
cord-347298-7kqrl3rv	629	18	with	with	IN
cord-347298-7kqrl3rv	629	19	varicocele	varicocele	NN
cord-347298-7kqrl3rv	629	20	(	(	-LRB-
cord-347298-7kqrl3rv	629	21	Santoro	Santoro	NNP
cord-347298-7kqrl3rv	629	22	et	et	NNP
cord-347298-7kqrl3rv	629	23	al	al	NNP
cord-347298-7kqrl3rv	629	24	.	.	NNP
cord-347298-7kqrl3rv	629	25	2001	2001	CD
cord-347298-7kqrl3rv	629	26	;	;	:
cord-347298-7kqrl3rv	629	27	Türker	Türker	NNP
cord-347298-7kqrl3rv	629	28	Köksal	Köksal	NNP
cord-347298-7kqrl3rv	629	29	et	et	NNP
cord-347298-7kqrl3rv	629	30	al	al	NNP
cord-347298-7kqrl3rv	629	31	.	.	.
cord-347298-7kqrl3rv	629	32	2004	2004	CD
cord-347298-7kqrl3rv	629	33	)	)	-RRB-
cord-347298-7kqrl3rv	629	34	.	.	.
cord-347298-7kqrl3rv	630	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	630	2	is	be	VBZ
cord-347298-7kqrl3rv	630	3	evident	evident	JJ
cord-347298-7kqrl3rv	630	4	that	that	IN
cord-347298-7kqrl3rv	630	5	the	the	DT
cord-347298-7kqrl3rv	630	6	major	major	JJ
cord-347298-7kqrl3rv	630	7	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	630	8	signaling	signal	VBG
cord-347298-7kqrl3rv	630	9	pathways	pathway	NNS
cord-347298-7kqrl3rv	630	10	mediated	mediate	VBN
cord-347298-7kqrl3rv	630	11	via	via	IN
cord-347298-7kqrl3rv	630	12	NFB	NFB	NNP
cord-347298-7kqrl3rv	630	13	and	and	CC
cord-347298-7kqrl3rv	630	14	the	the	DT
cord-347298-7kqrl3rv	630	15	p38	p38	CD
cord-347298-7kqrl3rv	630	16	/	/	,
cord-347298-7kqrl3rv	630	17	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	630	18	MAP	MAP	NNP
cord-347298-7kqrl3rv	630	19	kinases	kinase	NNS
cord-347298-7kqrl3rv	630	20	play	play	VBP
cord-347298-7kqrl3rv	630	21	important	important	JJ
cord-347298-7kqrl3rv	630	22	,	,	,
cord-347298-7kqrl3rv	630	23	albeit	albeit	IN
cord-347298-7kqrl3rv	630	24	complex	complex	JJ
cord-347298-7kqrl3rv	630	25	,	,	,
cord-347298-7kqrl3rv	630	26	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	630	27	roles	role	NNS
cord-347298-7kqrl3rv	630	28	.	.	.
cord-347298-7kqrl3rv	631	1	Notably	notably	RB
cord-347298-7kqrl3rv	631	2	,	,	,
cord-347298-7kqrl3rv	631	3	NFB	NFB	NNP
cord-347298-7kqrl3rv	631	4	has	have	VBZ
cord-347298-7kqrl3rv	631	5	been	be	VBN
cord-347298-7kqrl3rv	631	6	implicated	implicate	VBN
cord-347298-7kqrl3rv	631	7	as	as	IN
cord-347298-7kqrl3rv	631	8	an	an	DT
cord-347298-7kqrl3rv	631	9	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	631	10	-	-	HYPH
cord-347298-7kqrl3rv	631	11	inducing	induce	VBG
cord-347298-7kqrl3rv	631	12	signal	signal	NN
cord-347298-7kqrl3rv	631	13	for	for	IN
cord-347298-7kqrl3rv	631	14	germ	germ	NN
cord-347298-7kqrl3rv	631	15	cells	cell	NNS
cord-347298-7kqrl3rv	631	16	in	in	IN
cord-347298-7kqrl3rv	631	17	numerous	numerous	JJ
cord-347298-7kqrl3rv	631	18	studies	study	NNS
cord-347298-7kqrl3rv	631	19	(	(	-LRB-
cord-347298-7kqrl3rv	631	20	Lysiak	Lysiak	NNP
cord-347298-7kqrl3rv	631	21	et	et	FW
cord-347298-7kqrl3rv	631	22	al	al	NNP
cord-347298-7kqrl3rv	631	23	.	.	NNP
cord-347298-7kqrl3rv	631	24	2005	2005	CD
cord-347298-7kqrl3rv	631	25	;	;	:
cord-347298-7kqrl3rv	631	26	Pentikäinen	Pentikäinen	NNP
cord-347298-7kqrl3rv	631	27	et	et	NNP
cord-347298-7kqrl3rv	631	28	al	al	NNP
cord-347298-7kqrl3rv	631	29	.	.	.
cord-347298-7kqrl3rv	632	1	2002	2002	CD
cord-347298-7kqrl3rv	632	2	;	;	:
cord-347298-7kqrl3rv	632	3	Rasoulpour	Rasoulpour	NNP
cord-347298-7kqrl3rv	632	4	and	and	CC
cord-347298-7kqrl3rv	632	5	Boekelheide	Boekelheide	NNP
cord-347298-7kqrl3rv	632	6	2005	2005	CD
cord-347298-7kqrl3rv	632	7	;	;	:
cord-347298-7kqrl3rv	632	8	Starace	Starace	NNP
cord-347298-7kqrl3rv	632	9	et	et	NNP
cord-347298-7kqrl3rv	632	10	al	al	NNP
cord-347298-7kqrl3rv	632	11	.	.	NNP
cord-347298-7kqrl3rv	632	12	2005	2005	CD
cord-347298-7kqrl3rv	632	13	)	)	-RRB-
cord-347298-7kqrl3rv	632	14	,	,	,
cord-347298-7kqrl3rv	632	15	even	even	RB
cord-347298-7kqrl3rv	632	16	though	though	IN
cord-347298-7kqrl3rv	632	17	it	-PRON-	PRP
cord-347298-7kqrl3rv	632	18	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	632	19	androgen	androgen	NN
cord-347298-7kqrl3rv	632	20	receptor	receptor	NN
cord-347298-7kqrl3rv	632	21	expression	expression	NN
cord-347298-7kqrl3rv	632	22	in	in	IN
cord-347298-7kqrl3rv	632	23	the	the	DT
cord-347298-7kqrl3rv	632	24	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	632	25	cell	cell	NN
cord-347298-7kqrl3rv	632	26	(	(	-LRB-
cord-347298-7kqrl3rv	632	27	Delfino	Delfino	NNP
cord-347298-7kqrl3rv	632	28	et	et	FW
cord-347298-7kqrl3rv	632	29	al	al	NNP
cord-347298-7kqrl3rv	632	30	.	.	NNP
cord-347298-7kqrl3rv	632	31	2003	2003	CD
cord-347298-7kqrl3rv	632	32	)	)	-RRB-
cord-347298-7kqrl3rv	632	33	.	.	.
cord-347298-7kqrl3rv	633	1	Activation	activation	NN
cord-347298-7kqrl3rv	633	2	of	of	IN
cord-347298-7kqrl3rv	633	3	p38	p38	CD
cord-347298-7kqrl3rv	634	1	/Jnk	/Jnk	NNP
cord-347298-7kqrl3rv	634	2	is	be	VBZ
cord-347298-7kqrl3rv	634	3	implicated	implicate	VBN
cord-347298-7kqrl3rv	634	4	in	in	IN
cord-347298-7kqrl3rv	634	5	the	the	DT
cord-347298-7kqrl3rv	634	6	stimulation	stimulation	NN
cord-347298-7kqrl3rv	634	7	of	of	IN
cord-347298-7kqrl3rv	634	8	proliferation	proliferation	NN
cord-347298-7kqrl3rv	634	9	by	by	IN
cord-347298-7kqrl3rv	634	10	immature	immature	JJ
cord-347298-7kqrl3rv	634	11	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	634	12	cells	cell	NNS
cord-347298-7kqrl3rv	634	13	and	and	CC
cord-347298-7kqrl3rv	634	14	the	the	DT
cord-347298-7kqrl3rv	634	15	regulation	regulation	NN
cord-347298-7kqrl3rv	634	16	of	of	IN
cord-347298-7kqrl3rv	634	17	blood	blood	NN
cord-347298-7kqrl3rv	634	18	-	-	HYPH
cord-347298-7kqrl3rv	634	19	testis	testis	NN
cord-347298-7kqrl3rv	634	20	barrier	barrier	NN
cord-347298-7kqrl3rv	634	21	dynamics	dynamic	NNS
cord-347298-7kqrl3rv	634	22	,	,	,
cord-347298-7kqrl3rv	634	23	steroidogenesis	steroidogenesis	NNP
cord-347298-7kqrl3rv	634	24	,	,	,
cord-347298-7kqrl3rv	634	25	and	and	CC
cord-347298-7kqrl3rv	634	26	multiple	multiple	JJ
cord-347298-7kqrl3rv	634	27	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	634	28	responses	response	NNS
cord-347298-7kqrl3rv	634	29	,	,	,
cord-347298-7kqrl3rv	634	30	including	include	VBG
cord-347298-7kqrl3rv	634	31	the	the	DT
cord-347298-7kqrl3rv	634	32	production	production	NN
cord-347298-7kqrl3rv	634	33	of	of	IN
cord-347298-7kqrl3rv	634	34	IL6	il6	NN
cord-347298-7kqrl3rv	634	35	,	,	,
cord-347298-7kqrl3rv	634	36	iNOS	iNOS	NNP
cord-347298-7kqrl3rv	634	37	,	,	,
cord-347298-7kqrl3rv	634	38	monocyte	monocyte	NNP
cord-347298-7kqrl3rv	634	39	chemoattractant	chemoattractant	NNP
cord-347298-7kqrl3rv	634	40	protein	protein	NNP
cord-347298-7kqrl3rv	634	41	1	1	CD
cord-347298-7kqrl3rv	634	42	,	,	,
cord-347298-7kqrl3rv	634	43	and	and	CC
cord-347298-7kqrl3rv	634	44	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	634	45	adhesion	adhesion	NN
cord-347298-7kqrl3rv	634	46	molecules	molecule	NNS
cord-347298-7kqrl3rv	634	47	,	,	,
cord-347298-7kqrl3rv	634	48	in	in	IN
cord-347298-7kqrl3rv	634	49	the	the	DT
cord-347298-7kqrl3rv	634	50	mature	mature	JJ
cord-347298-7kqrl3rv	634	51	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	634	52	cell	cell	NN
cord-347298-7kqrl3rv	634	53	(	(	-LRB-
cord-347298-7kqrl3rv	634	54	De	De	NNP
cord-347298-7kqrl3rv	634	55	Cesaris	Cesaris	NNP
cord-347298-7kqrl3rv	634	56	et	et	NNP
cord-347298-7kqrl3rv	634	57	al	al	NNP
cord-347298-7kqrl3rv	634	58	.	.	.
cord-347298-7kqrl3rv	635	1	1998	1998	CD
cord-347298-7kqrl3rv	635	2	,	,	,
cord-347298-7kqrl3rv	635	3	1999	1999	CD
cord-347298-7kqrl3rv	635	4	Ishikawa	Ishikawa	NNP
cord-347298-7kqrl3rv	635	5	and	and	CC
cord-347298-7kqrl3rv	635	6	Morris	Morris	NNP
cord-347298-7kqrl3rv	635	7	2006	2006	CD
cord-347298-7kqrl3rv	635	8	;	;	:
cord-347298-7kqrl3rv	635	9	Ishikawa	Ishikawa	NNP
cord-347298-7kqrl3rv	635	10	et	et	NNP
cord-347298-7kqrl3rv	635	11	al	al	NNP
cord-347298-7kqrl3rv	635	12	.	.	NNP
cord-347298-7kqrl3rv	635	13	2005	2005	CD
cord-347298-7kqrl3rv	635	14	;	;	:
cord-347298-7kqrl3rv	635	15	Petersen	Petersen	NNP
cord-347298-7kqrl3rv	635	16	et	et	NNP
cord-347298-7kqrl3rv	635	17	al	al	NNP
cord-347298-7kqrl3rv	635	18	.	.	.
cord-347298-7kqrl3rv	636	1	2005	2005	CD
cord-347298-7kqrl3rv	636	2	;	;	:
cord-347298-7kqrl3rv	636	3	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	636	4	et	et	NNP
cord-347298-7kqrl3rv	636	5	al	al	NNP
cord-347298-7kqrl3rv	636	6	.	.	.
cord-347298-7kqrl3rv	636	7	2006	2006	CD
cord-347298-7kqrl3rv	636	8	)	)	-RRB-
cord-347298-7kqrl3rv	636	9	.	.	.
cord-347298-7kqrl3rv	637	1	While	while	IN
cord-347298-7kqrl3rv	637	2	these	these	DT
cord-347298-7kqrl3rv	637	3	pathways	pathway	NNS
cord-347298-7kqrl3rv	637	4	mediate	mediate	VBP
cord-347298-7kqrl3rv	637	5	many	many	JJ
cord-347298-7kqrl3rv	637	6	of	of	IN
cord-347298-7kqrl3rv	637	7	the	the	DT
cord-347298-7kqrl3rv	637	8	effects	effect	NNS
cord-347298-7kqrl3rv	637	9	of	of	IN
cord-347298-7kqrl3rv	637	10	inflammation	inflammation	NN
cord-347298-7kqrl3rv	637	11	on	on	IN
cord-347298-7kqrl3rv	637	12	the	the	DT
cord-347298-7kqrl3rv	637	13	testis	testis	NN
cord-347298-7kqrl3rv	637	14	,	,	,
cord-347298-7kqrl3rv	637	15	endogenous	endogenous	JJ
cord-347298-7kqrl3rv	637	16	regulation	regulation	NN
cord-347298-7kqrl3rv	637	17	of	of	IN
cord-347298-7kqrl3rv	637	18	these	these	DT
cord-347298-7kqrl3rv	637	19	pathways	pathway	NNS
cord-347298-7kqrl3rv	637	20	also	also	RB
cord-347298-7kqrl3rv	637	21	appears	appear	VBZ
cord-347298-7kqrl3rv	637	22	to	to	TO
cord-347298-7kqrl3rv	637	23	be	be	VB
cord-347298-7kqrl3rv	637	24	involved	involve	VBN
cord-347298-7kqrl3rv	637	25	in	in	IN
cord-347298-7kqrl3rv	637	26	the	the	DT
cord-347298-7kqrl3rv	637	27	normal	normal	JJ
cord-347298-7kqrl3rv	637	28	functions	function	NNS
cord-347298-7kqrl3rv	637	29	of	of	IN
cord-347298-7kqrl3rv	637	30	the	the	DT
cord-347298-7kqrl3rv	637	31	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	637	32	epithelium	epithelium	NN
cord-347298-7kqrl3rv	637	33	,	,	,
cord-347298-7kqrl3rv	637	34	as	as	IN
cord-347298-7kqrl3rv	637	35	will	will	MD
cord-347298-7kqrl3rv	637	36	be	be	VB
cord-347298-7kqrl3rv	637	37	discussed	discuss	VBN
cord-347298-7kqrl3rv	637	38	later	later	RB
cord-347298-7kqrl3rv	637	39	.	.	.
cord-347298-7kqrl3rv	638	1	The	the	DT
cord-347298-7kqrl3rv	638	2	IFNs	ifn	NNS
cord-347298-7kqrl3rv	638	3	are	be	VBP
cord-347298-7kqrl3rv	638	4	functionally	functionally	RB
cord-347298-7kqrl3rv	638	5	related	relate	VBN
cord-347298-7kqrl3rv	638	6	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	638	7	with	with	IN
cord-347298-7kqrl3rv	638	8	antiviral	antiviral	JJ
cord-347298-7kqrl3rv	638	9	activity	activity	NN
cord-347298-7kqrl3rv	638	10	and	and	CC
cord-347298-7kqrl3rv	638	11	they	-PRON-	PRP
cord-347298-7kqrl3rv	638	12	comprise	comprise	VBP
cord-347298-7kqrl3rv	638	13	three	three	CD
cord-347298-7kqrl3rv	638	14	main	main	JJ
cord-347298-7kqrl3rv	638	15	groups	group	NNS
cord-347298-7kqrl3rv	638	16	(	(	-LRB-
cord-347298-7kqrl3rv	638	17	,	,	,
cord-347298-7kqrl3rv	638	18	,	,	,
cord-347298-7kqrl3rv	638	19	and	and	CC
cord-347298-7kqrl3rv	638	20	)	)	-RRB-
cord-347298-7kqrl3rv	638	21	,	,	,
cord-347298-7kqrl3rv	638	22	based	base	VBN
cord-347298-7kqrl3rv	638	23	on	on	IN
cord-347298-7kqrl3rv	638	24	their	-PRON-	PRP$
cord-347298-7kqrl3rv	638	25	structural	structural	JJ
cord-347298-7kqrl3rv	638	26	relationships	relationship	NNS
cord-347298-7kqrl3rv	638	27	and	and	CC
cord-347298-7kqrl3rv	638	28	major	major	JJ
cord-347298-7kqrl3rv	638	29	cellular	cellular	JJ
cord-347298-7kqrl3rv	638	30	sources	source	NNS
cord-347298-7kqrl3rv	638	31	(	(	-LRB-
cord-347298-7kqrl3rv	638	32	Hertzog	Hertzog	NNP
cord-347298-7kqrl3rv	638	33	et	et	NNP
cord-347298-7kqrl3rv	638	34	al	al	NNP
cord-347298-7kqrl3rv	638	35	.	.	NNP
cord-347298-7kqrl3rv	638	36	2003	2003	CD
cord-347298-7kqrl3rv	638	37	;	;	:
cord-347298-7kqrl3rv	638	38	Malmgaard	Malmgaard	NNP
cord-347298-7kqrl3rv	638	39	2004	2004	CD
cord-347298-7kqrl3rv	638	40	)	)	-RRB-
cord-347298-7kqrl3rv	638	41	.	.	.
cord-347298-7kqrl3rv	639	1	The	the	DT
cord-347298-7kqrl3rv	639	2	type	type	NN
cord-347298-7kqrl3rv	639	3	I	-PRON-	PRP
cord-347298-7kqrl3rv	639	4	IFNs	ifns	VBP
cord-347298-7kqrl3rv	639	5	(	(	-LRB-
cord-347298-7kqrl3rv	639	6	IFN	IFN	NNP
cord-347298-7kqrl3rv	639	7	and	and	CC
cord-347298-7kqrl3rv	639	8	)	)	-RRB-
cord-347298-7kqrl3rv	639	9	are	be	VBP
cord-347298-7kqrl3rv	639	10	produced	produce	VBN
cord-347298-7kqrl3rv	639	11	by	by	IN
cord-347298-7kqrl3rv	639	12	a	a	DT
cord-347298-7kqrl3rv	639	13	variety	variety	NN
cord-347298-7kqrl3rv	639	14	of	of	IN
cord-347298-7kqrl3rv	639	15	cell	cell	NN
cord-347298-7kqrl3rv	639	16	types	type	NNS
cord-347298-7kqrl3rv	639	17	in	in	IN
cord-347298-7kqrl3rv	639	18	addition	addition	NN
cord-347298-7kqrl3rv	639	19	to	to	IN
cord-347298-7kqrl3rv	639	20	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	639	21	,	,	,
cord-347298-7kqrl3rv	639	22	and	and	CC
cord-347298-7kqrl3rv	639	23	exert	exert	VBP
cord-347298-7kqrl3rv	639	24	primarily	primarily	RB
cord-347298-7kqrl3rv	639	25	antiviral	antiviral	JJ
cord-347298-7kqrl3rv	639	26	and	and	CC
cord-347298-7kqrl3rv	639	27	antiproliferative	antiproliferative	JJ
cord-347298-7kqrl3rv	639	28	effects	effect	NNS
cord-347298-7kqrl3rv	639	29	via	via	IN
cord-347298-7kqrl3rv	639	30	the	the	DT
cord-347298-7kqrl3rv	639	31	IFN	IFN	NNP
cord-347298-7kqrl3rv	639	32	receptor	receptor	NN
cord-347298-7kqrl3rv	639	33	(	(	-LRB-
cord-347298-7kqrl3rv	639	34	IFNAR	IFNAR	NNP
cord-347298-7kqrl3rv	639	35	)	)	-RRB-
cord-347298-7kqrl3rv	639	36	.	.	.
cord-347298-7kqrl3rv	640	1	The	the	DT
cord-347298-7kqrl3rv	640	2	type	type	NN
cord-347298-7kqrl3rv	640	3	II	II	NNP
cord-347298-7kqrl3rv	640	4	IFN	IFN	NNP
cord-347298-7kqrl3rv	640	5	is	be	VBZ
cord-347298-7kqrl3rv	640	6	produced	produce	VBN
cord-347298-7kqrl3rv	640	7	by	by	IN
cord-347298-7kqrl3rv	640	8	NK	NK	NNP
cord-347298-7kqrl3rv	640	9	and	and	CC
cord-347298-7kqrl3rv	640	10	NKT	NKT	NNP
cord-347298-7kqrl3rv	640	11	cells	cell	NNS
cord-347298-7kqrl3rv	640	12	,	,	,
cord-347298-7kqrl3rv	640	13	activated	activate	VBD
cord-347298-7kqrl3rv	640	14	T	t	NN
cord-347298-7kqrl3rv	640	15	cells	cell	NNS
cord-347298-7kqrl3rv	640	16	and	and	CC
cord-347298-7kqrl3rv	640	17	,	,	,
cord-347298-7kqrl3rv	640	18	under	under	IN
cord-347298-7kqrl3rv	640	19	certain	certain	JJ
cord-347298-7kqrl3rv	640	20	conditions	condition	NNS
cord-347298-7kqrl3rv	640	21	,	,	,
cord-347298-7kqrl3rv	640	22	by	by	IN
cord-347298-7kqrl3rv	640	23	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	640	24	and	and	CC
cord-347298-7kqrl3rv	640	25	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	640	26	cells	cell	NNS
cord-347298-7kqrl3rv	640	27	(	(	-LRB-
cord-347298-7kqrl3rv	640	28	Schoenborn	Schoenborn	NNP
cord-347298-7kqrl3rv	640	29	and	and	CC
cord-347298-7kqrl3rv	640	30	Wilson	Wilson	NNP
cord-347298-7kqrl3rv	640	31	2007	2007	CD
cord-347298-7kqrl3rv	640	32	;	;	:
cord-347298-7kqrl3rv	640	33	Varma	Varma	NNP
cord-347298-7kqrl3rv	640	34	et	et	NNP
cord-347298-7kqrl3rv	640	35	al	al	NNP
cord-347298-7kqrl3rv	640	36	.	.	.
cord-347298-7kqrl3rv	640	37	2002	2002	CD
cord-347298-7kqrl3rv	640	38	)	)	-RRB-
cord-347298-7kqrl3rv	640	39	.	.	.
cord-347298-7kqrl3rv	641	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	641	2	acts	act	VBZ
cord-347298-7kqrl3rv	641	3	through	through	IN
cord-347298-7kqrl3rv	641	4	a	a	DT
cord-347298-7kqrl3rv	641	5	separate	separate	JJ
cord-347298-7kqrl3rv	641	6	receptor	receptor	NN
cord-347298-7kqrl3rv	641	7	,	,	,
cord-347298-7kqrl3rv	641	8	and	and	CC
cord-347298-7kqrl3rv	641	9	regulates	regulate	VBZ
cord-347298-7kqrl3rv	641	10	the	the	DT
cord-347298-7kqrl3rv	641	11	activity	activity	NN
cord-347298-7kqrl3rv	641	12	of	of	IN
cord-347298-7kqrl3rv	641	13	APCs	apc	NNS
cord-347298-7kqrl3rv	641	14	as	as	IN
cord-347298-7kqrl3rv	641	15	part	part	NN
cord-347298-7kqrl3rv	641	16	of	of	IN
cord-347298-7kqrl3rv	641	17	the	the	DT
cord-347298-7kqrl3rv	641	18	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	641	19	immune	immune	JJ
cord-347298-7kqrl3rv	641	20	response	response	NN
cord-347298-7kqrl3rv	641	21	in	in	IN
cord-347298-7kqrl3rv	641	22	addition	addition	NN
cord-347298-7kqrl3rv	641	23	to	to	IN
cord-347298-7kqrl3rv	641	24	its	-PRON-	PRP$
cord-347298-7kqrl3rv	641	25	antiviral	antiviral	JJ
cord-347298-7kqrl3rv	641	26	functions	function	NNS
cord-347298-7kqrl3rv	641	27	.	.	.
cord-347298-7kqrl3rv	642	1	Hence	hence	RB
cord-347298-7kqrl3rv	642	2	,	,	,
cord-347298-7kqrl3rv	642	3	IFN	IFN	NNP
cord-347298-7kqrl3rv	642	4	is	be	VBZ
cord-347298-7kqrl3rv	642	5	a	a	DT
cord-347298-7kqrl3rv	642	6	type	type	NN
cord-347298-7kqrl3rv	642	7	II	II	NNP
cord-347298-7kqrl3rv	642	8	IFN	IFN	NNP
cord-347298-7kqrl3rv	642	9	,	,	,
cord-347298-7kqrl3rv	642	10	but	but	CC
cord-347298-7kqrl3rv	642	11	a	a	DT
cord-347298-7kqrl3rv	642	12	type	type	NN
cord-347298-7kqrl3rv	642	13	1	1	CD
cord-347298-7kqrl3rv	642	14	cytokine	cytokine	NN
cord-347298-7kqrl3rv	642	15	.	.	.
cord-347298-7kqrl3rv	643	1	Type	type	NN
cord-347298-7kqrl3rv	643	2	I	-PRON-	PRP
cord-347298-7kqrl3rv	643	3	IFN	IFN	NNP
cord-347298-7kqrl3rv	643	4	production	production	NN
cord-347298-7kqrl3rv	643	5	is	be	VBZ
cord-347298-7kqrl3rv	643	6	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	643	7	through	through	IN
cord-347298-7kqrl3rv	643	8	TLR3	TLR3	NNP
cord-347298-7kqrl3rv	643	9	,	,	,
cord-347298-7kqrl3rv	643	10	which	which	WDT
cord-347298-7kqrl3rv	643	11	detects	detect	VBZ
cord-347298-7kqrl3rv	643	12	double	double	RB
cord-347298-7kqrl3rv	643	13	-	-	HYPH
cord-347298-7kqrl3rv	643	14	stranded	strand	VBN
cord-347298-7kqrl3rv	643	15	viral	viral	JJ
cord-347298-7kqrl3rv	643	16	RNA	RNA	NNP
cord-347298-7kqrl3rv	643	17	,	,	,
cord-347298-7kqrl3rv	643	18	and	and	CC
cord-347298-7kqrl3rv	643	19	TLR4	TLR4	NNP
cord-347298-7kqrl3rv	643	20	,	,	,
cord-347298-7kqrl3rv	643	21	the	the	DT
cord-347298-7kqrl3rv	643	22	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	643	23	LPS	LPS	NNP
cord-347298-7kqrl3rv	643	24	receptor	receptor	NN
cord-347298-7kqrl3rv	643	25	(	(	-LRB-
cord-347298-7kqrl3rv	643	26	Hertzog	Hertzog	NNP
cord-347298-7kqrl3rv	643	27	et	et	NNP
cord-347298-7kqrl3rv	643	28	al	al	NNP
cord-347298-7kqrl3rv	643	29	.	.	NNP
cord-347298-7kqrl3rv	643	30	2003	2003	CD
cord-347298-7kqrl3rv	643	31	)	)	-RRB-
cord-347298-7kqrl3rv	643	32	.	.	.
cord-347298-7kqrl3rv	644	1	These	these	DT
cord-347298-7kqrl3rv	644	2	two	two	CD
cord-347298-7kqrl3rv	644	3	TLRs	tlr	NNS
cord-347298-7kqrl3rv	644	4	,	,	,
cord-347298-7kqrl3rv	644	5	which	which	WDT
cord-347298-7kqrl3rv	644	6	are	be	VBP
cord-347298-7kqrl3rv	644	7	expressed	express	VBN
cord-347298-7kqrl3rv	644	8	in	in	IN
cord-347298-7kqrl3rv	644	9	the	the	DT
cord-347298-7kqrl3rv	644	10	testis	testis	NN
cord-347298-7kqrl3rv	644	11	(	(	-LRB-
cord-347298-7kqrl3rv	644	12	Bhushan	Bhushan	NNP
cord-347298-7kqrl3rv	644	13	et	et	NNP
cord-347298-7kqrl3rv	644	14	al	al	NNP
cord-347298-7kqrl3rv	644	15	.	.	NNP
cord-347298-7kqrl3rv	644	16	2008	2008	CD
cord-347298-7kqrl3rv	644	17	;	;	:
cord-347298-7kqrl3rv	644	18	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	644	19	et	et	NNP
cord-347298-7kqrl3rv	644	20	al	al	NNP
cord-347298-7kqrl3rv	644	21	.	.	.
cord-347298-7kqrl3rv	644	22	2006	2006	CD
cord-347298-7kqrl3rv	644	23	;	;	:
cord-347298-7kqrl3rv	644	24	Starace	Starace	NNP
cord-347298-7kqrl3rv	644	25	et	et	NNP
cord-347298-7kqrl3rv	644	26	al	al	NNP
cord-347298-7kqrl3rv	644	27	.	.	NNP
cord-347298-7kqrl3rv	644	28	2008	2008	CD
cord-347298-7kqrl3rv	644	29	;	;	:
cord-347298-7kqrl3rv	644	30	Wu	Wu	NNP
cord-347298-7kqrl3rv	644	31	et	et	NNP
cord-347298-7kqrl3rv	644	32	al	al	NNP
cord-347298-7kqrl3rv	644	33	.	.	NNP
cord-347298-7kqrl3rv	644	34	2008	2008	CD
cord-347298-7kqrl3rv	644	35	)	)	-RRB-
cord-347298-7kqrl3rv	644	36	,	,	,
cord-347298-7kqrl3rv	644	37	are	be	VBP
cord-347298-7kqrl3rv	644	38	able	able	JJ
cord-347298-7kqrl3rv	644	39	to	to	TO
cord-347298-7kqrl3rv	644	40	induce	induce	VB
cord-347298-7kqrl3rv	644	41	the	the	DT
cord-347298-7kqrl3rv	644	42	IFN	IFN	NNP
cord-347298-7kqrl3rv	644	43	transcription	transcription	NN
cord-347298-7kqrl3rv	644	44	factor	factor	NN
cord-347298-7kqrl3rv	644	45	IRF3	IRF3	NNP
cord-347298-7kqrl3rv	644	46	,	,	,
cord-347298-7kqrl3rv	644	47	via	via	IN
cord-347298-7kqrl3rv	644	48	engagement	engagement	NN
cord-347298-7kqrl3rv	644	49	of	of	IN
cord-347298-7kqrl3rv	644	50	the	the	DT
cord-347298-7kqrl3rv	644	51	TRIF	TRIF	NNP
cord-347298-7kqrl3rv	644	52	adapter	adapter	NN
cord-347298-7kqrl3rv	644	53	protein	protein	NN
cord-347298-7kqrl3rv	644	54	(	(	-LRB-
cord-347298-7kqrl3rv	644	55	Akira	Akira	NNP
cord-347298-7kqrl3rv	644	56	and	and	CC
cord-347298-7kqrl3rv	644	57	Takeda	Takeda	NNP
cord-347298-7kqrl3rv	644	58	2004	2004	CD
cord-347298-7kqrl3rv	644	59	;	;	:
cord-347298-7kqrl3rv	644	60	Hertzog	Hertzog	NNP
cord-347298-7kqrl3rv	644	61	et	et	NNP
cord-347298-7kqrl3rv	644	62	al	al	NNP
cord-347298-7kqrl3rv	644	63	.	.	.
cord-347298-7kqrl3rv	645	1	2003	2003	CD
cord-347298-7kqrl3rv	645	2	;	;	:
cord-347298-7kqrl3rv	645	3	O'Neill	O'Neill	NNP
cord-347298-7kqrl3rv	645	4	and	and	CC
cord-347298-7kqrl3rv	645	5	Bowie	Bowie	NNP
cord-347298-7kqrl3rv	645	6	2007	2007	CD
cord-347298-7kqrl3rv	645	7	)	)	-RRB-
cord-347298-7kqrl3rv	645	8	.	.	.
cord-347298-7kqrl3rv	646	1	The	the	DT
cord-347298-7kqrl3rv	646	2	regulation	regulation	NN
cord-347298-7kqrl3rv	646	3	of	of	IN
cord-347298-7kqrl3rv	646	4	IFN	IFN	NNP
cord-347298-7kqrl3rv	646	5	is	be	VBZ
cord-347298-7kqrl3rv	646	6	cell	cell	NN
cord-347298-7kqrl3rv	646	7	specific	specific	JJ
cord-347298-7kqrl3rv	646	8	and	and	CC
cord-347298-7kqrl3rv	646	9	complex	complex	JJ
cord-347298-7kqrl3rv	646	10	,	,	,
cord-347298-7kqrl3rv	646	11	but	but	CC
cord-347298-7kqrl3rv	646	12	involves	involve	VBZ
cord-347298-7kqrl3rv	646	13	Jak	Jak	NNP
cord-347298-7kqrl3rv	646	14	/	/	SYM
cord-347298-7kqrl3rv	646	15	Stat	Stat	NNP
cord-347298-7kqrl3rv	646	16	signaling	signal	VBG
cord-347298-7kqrl3rv	646	17	and	and	CC
cord-347298-7kqrl3rv	646	18	various	various	JJ
cord-347298-7kqrl3rv	646	19	transcription	transcription	NN
cord-347298-7kqrl3rv	646	20	factors	factor	NNS
cord-347298-7kqrl3rv	646	21	,	,	,
cord-347298-7kqrl3rv	646	22	including	include	VBG
cord-347298-7kqrl3rv	646	23	NFB	NFB	NNP
cord-347298-7kqrl3rv	646	24	and	and	CC
cord-347298-7kqrl3rv	646	25	AP1	AP1	NNP
cord-347298-7kqrl3rv	646	26	(	(	-LRB-
cord-347298-7kqrl3rv	646	27	Schoenborn	Schoenborn	NNP
cord-347298-7kqrl3rv	646	28	and	and	CC
cord-347298-7kqrl3rv	646	29	Wilson	Wilson	NNP
cord-347298-7kqrl3rv	646	30	2007	2007	CD
cord-347298-7kqrl3rv	646	31	;	;	:
cord-347298-7kqrl3rv	646	32	Varma	Varma	NNP
cord-347298-7kqrl3rv	646	33	et	et	NNP
cord-347298-7kqrl3rv	646	34	al	al	NNP
cord-347298-7kqrl3rv	646	35	.	.	.
cord-347298-7kqrl3rv	646	36	2002	2002	CD
cord-347298-7kqrl3rv	646	37	)	)	-RRB-
cord-347298-7kqrl3rv	646	38	.	.	.
cord-347298-7kqrl3rv	647	1	Its	-PRON-	PRP$
cord-347298-7kqrl3rv	647	2	production	production	NN
cord-347298-7kqrl3rv	647	3	is	be	VBZ
cord-347298-7kqrl3rv	647	4	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	647	5	by	by	IN
cord-347298-7kqrl3rv	647	6	type	type	NN
cord-347298-7kqrl3rv	647	7	I	-PRON-	PRP
cord-347298-7kqrl3rv	647	8	IFNs	ifn	NNS
cord-347298-7kqrl3rv	647	9	and	and	CC
cord-347298-7kqrl3rv	647	10	by	by	IN
cord-347298-7kqrl3rv	647	11	IL18	IL18	NNP
cord-347298-7kqrl3rv	647	12	,	,	,
cord-347298-7kqrl3rv	647	13	among	among	IN
cord-347298-7kqrl3rv	647	14	other	other	JJ
cord-347298-7kqrl3rv	647	15	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	647	16	.	.	.
cord-347298-7kqrl3rv	648	1	Viral	viral	JJ
cord-347298-7kqrl3rv	648	2	infections	infection	NNS
cord-347298-7kqrl3rv	648	3	stimulate	stimulate	VBP
cord-347298-7kqrl3rv	648	4	type	type	NN
cord-347298-7kqrl3rv	648	5	1	1	CD
cord-347298-7kqrl3rv	648	6	IFN	IFN	NNP
cord-347298-7kqrl3rv	648	7	and	and	CC
cord-347298-7kqrl3rv	648	8	,	,	,
cord-347298-7kqrl3rv	648	9	somewhat	somewhat	RB
cord-347298-7kqrl3rv	648	10	more	more	RBR
cord-347298-7kqrl3rv	648	11	surprisingly	surprisingly	RB
cord-347298-7kqrl3rv	648	12	,	,	,
cord-347298-7kqrl3rv	648	13	IFN	IFN	NNP
cord-347298-7kqrl3rv	648	14	production	production	NN
cord-347298-7kqrl3rv	648	15	by	by	IN
cord-347298-7kqrl3rv	648	16	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	648	17	cells	cell	NNS
cord-347298-7kqrl3rv	648	18	,	,	,
cord-347298-7kqrl3rv	648	19	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	648	20	cells	cell	NNS
cord-347298-7kqrl3rv	648	21	,	,	,
cord-347298-7kqrl3rv	648	22	Leydig	leydig	NN
cord-347298-7kqrl3rv	648	23	cells	cell	NNS
cord-347298-7kqrl3rv	648	24	,	,	,
cord-347298-7kqrl3rv	648	25	and	and	CC
cord-347298-7kqrl3rv	648	26	testicular	testicular	JJ
cord-347298-7kqrl3rv	648	27	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	648	28	,	,	,
cord-347298-7kqrl3rv	648	29	leading	lead	VBG
cord-347298-7kqrl3rv	648	30	to	to	IN
cord-347298-7kqrl3rv	648	31	typical	typical	JJ
cord-347298-7kqrl3rv	648	32	antiviral	antiviral	JJ
cord-347298-7kqrl3rv	648	33	responses	response	NNS
cord-347298-7kqrl3rv	648	34	in	in	IN
cord-347298-7kqrl3rv	648	35	the	the	DT
cord-347298-7kqrl3rv	648	36	testis	testis	NN
cord-347298-7kqrl3rv	648	37	(	(	-LRB-
cord-347298-7kqrl3rv	648	38	Dejucq	Dejucq	NNP
cord-347298-7kqrl3rv	648	39	et	et	FW
cord-347298-7kqrl3rv	648	40	al	al	NNP
cord-347298-7kqrl3rv	648	41	.	.	.
cord-347298-7kqrl3rv	649	1	1995	1995	CD
cord-347298-7kqrl3rv	649	2	(	(	-LRB-
cord-347298-7kqrl3rv	649	3	Dejucq	Dejucq	NNP
cord-347298-7kqrl3rv	649	4	et	et	FW
cord-347298-7kqrl3rv	649	5	al	al	NNP
cord-347298-7kqrl3rv	649	6	.	.	.
cord-347298-7kqrl3rv	650	1	,	,	,
cord-347298-7kqrl3rv	650	2	1998a	1998a	CD
cord-347298-7kqrl3rv	650	3	Hu	Hu	NNP
cord-347298-7kqrl3rv	650	4	et	et	FW
cord-347298-7kqrl3rv	650	5	al	al	NNP
cord-347298-7kqrl3rv	650	6	.	.	.
cord-347298-7kqrl3rv	651	1	1998	1998	CD
cord-347298-7kqrl3rv	651	2	;	;	:
cord-347298-7kqrl3rv	651	3	Starace	Starace	NNP
cord-347298-7kqrl3rv	651	4	et	et	NNP
cord-347298-7kqrl3rv	651	5	al	al	NNP
cord-347298-7kqrl3rv	651	6	.	.	NNP
cord-347298-7kqrl3rv	651	7	2008	2008	CD
cord-347298-7kqrl3rv	651	8	)	)	-RRB-
cord-347298-7kqrl3rv	651	9	.	.	.
cord-347298-7kqrl3rv	652	1	A	a	DT
cord-347298-7kqrl3rv	652	2	role	role	NN
cord-347298-7kqrl3rv	652	3	for	for	IN
cord-347298-7kqrl3rv	652	4	IFN	IFN	NNP
cord-347298-7kqrl3rv	652	5	in	in	IN
cord-347298-7kqrl3rv	652	6	maintaining	maintain	VBG
cord-347298-7kqrl3rv	652	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	652	8	immune	immune	JJ
cord-347298-7kqrl3rv	652	9	privilege	privilege	NN
cord-347298-7kqrl3rv	652	10	has	have	VBZ
cord-347298-7kqrl3rv	652	11	been	be	VBN
cord-347298-7kqrl3rv	652	12	indicated	indicate	VBN
cord-347298-7kqrl3rv	652	13	by	by	IN
cord-347298-7kqrl3rv	652	14	the	the	DT
cord-347298-7kqrl3rv	652	15	observation	observation	NN
cord-347298-7kqrl3rv	652	16	that	that	IN
cord-347298-7kqrl3rv	652	17	mouse	mouse	NN
cord-347298-7kqrl3rv	652	18	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	652	19	cells	cell	NNS
cord-347298-7kqrl3rv	652	20	upregulate	upregulate	VBP
cord-347298-7kqrl3rv	652	21	their	-PRON-	PRP$
cord-347298-7kqrl3rv	652	22	expression	expression	NN
cord-347298-7kqrl3rv	652	23	of	of	IN
cord-347298-7kqrl3rv	652	24	the	the	DT
cord-347298-7kqrl3rv	652	25	negative	negative	JJ
cord-347298-7kqrl3rv	652	26	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	652	27	ligand	ligand	NN
cord-347298-7kqrl3rv	652	28	B7-H1	B7-H1	NNP
cord-347298-7kqrl3rv	652	29	in	in	IN
cord-347298-7kqrl3rv	652	30	response	response	NN
cord-347298-7kqrl3rv	652	31	to	to	IN
cord-347298-7kqrl3rv	652	32	IFN	IFN	NNP
cord-347298-7kqrl3rv	652	33	in	in	IN
cord-347298-7kqrl3rv	652	34	vitro	vitro	FW
cord-347298-7kqrl3rv	652	35	,	,	,
cord-347298-7kqrl3rv	652	36	but	but	CC
cord-347298-7kqrl3rv	652	37	remain	remain	VBP
cord-347298-7kqrl3rv	652	38	devoid	devoid	JJ
cord-347298-7kqrl3rv	652	39	of	of	IN
cord-347298-7kqrl3rv	652	40	positive	positive	JJ
cord-347298-7kqrl3rv	652	41	costimulatory	costimulatory	NN
cord-347298-7kqrl3rv	652	42	molecules	molecule	NNS
cord-347298-7kqrl3rv	653	1	(	(	-LRB-
cord-347298-7kqrl3rv	653	2	Dal	Dal	NNP
cord-347298-7kqrl3rv	653	3	Secco	Secco	NNP
cord-347298-7kqrl3rv	653	4	et	et	FW
cord-347298-7kqrl3rv	653	5	al	al	NNP
cord-347298-7kqrl3rv	653	6	.	.	NNP
cord-347298-7kqrl3rv	653	7	2008	2008	CD
cord-347298-7kqrl3rv	653	8	)	)	-RRB-
cord-347298-7kqrl3rv	653	9	.	.	.
cord-347298-7kqrl3rv	654	1	On	on	IN
cord-347298-7kqrl3rv	654	2	the	the	DT
cord-347298-7kqrl3rv	654	3	other	other	JJ
cord-347298-7kqrl3rv	654	4	hand	hand	NN
cord-347298-7kqrl3rv	654	5	,	,	,
cord-347298-7kqrl3rv	654	6	in	in	IN
cord-347298-7kqrl3rv	654	7	vivo	vivo	NNP
cord-347298-7kqrl3rv	654	8	studies	study	NNS
cord-347298-7kqrl3rv	654	9	have	have	VBP
cord-347298-7kqrl3rv	654	10	identified	identify	VBN
cord-347298-7kqrl3rv	654	11	IFN	IFN	NNP
cord-347298-7kqrl3rv	654	12	as	as	IN
cord-347298-7kqrl3rv	654	13	a	a	DT
cord-347298-7kqrl3rv	654	14	causative	causative	JJ
cord-347298-7kqrl3rv	654	15	factor	factor	NN
cord-347298-7kqrl3rv	654	16	in	in	IN
cord-347298-7kqrl3rv	654	17	EAO	EAO	NNP
cord-347298-7kqrl3rv	654	18	in	in	IN
cord-347298-7kqrl3rv	654	19	mice	mouse	NNS
cord-347298-7kqrl3rv	655	1	(	(	-LRB-
cord-347298-7kqrl3rv	655	2	Itoh	Itoh	NNP
cord-347298-7kqrl3rv	655	3	et	et	NNP
cord-347298-7kqrl3rv	655	4	al	al	NNP
cord-347298-7kqrl3rv	655	5	.	.	NNP
cord-347298-7kqrl3rv	655	6	1998b	1998b	CD
cord-347298-7kqrl3rv	655	7	)	)	-RRB-
cord-347298-7kqrl3rv	655	8	.	.	.
cord-347298-7kqrl3rv	656	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	656	2	,	,	,
cord-347298-7kqrl3rv	656	3	IFN	IFN	NNP
cord-347298-7kqrl3rv	656	4	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	656	5	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	656	6	cell	cell	NN
cord-347298-7kqrl3rv	656	7	production	production	NN
cord-347298-7kqrl3rv	656	8	of	of	IN
cord-347298-7kqrl3rv	656	9	Fas	Fas	NNP
cord-347298-7kqrl3rv	656	10	and	and	CC
cord-347298-7kqrl3rv	656	11	caspase	caspase	NN
cord-347298-7kqrl3rv	656	12	1	1	CD
cord-347298-7kqrl3rv	656	13	,	,	,
cord-347298-7kqrl3rv	656	14	and	and	CC
cord-347298-7kqrl3rv	656	15	is	be	VBZ
cord-347298-7kqrl3rv	656	16	implicated	implicate	VBN
cord-347298-7kqrl3rv	656	17	as	as	IN
cord-347298-7kqrl3rv	656	18	the	the	DT
cord-347298-7kqrl3rv	656	19	mediator	mediator	NN
cord-347298-7kqrl3rv	656	20	of	of	IN
cord-347298-7kqrl3rv	656	21	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	656	22	cell	cell	NN
cord-347298-7kqrl3rv	656	23	and	and	CC
cord-347298-7kqrl3rv	656	24	germ	germ	NN
cord-347298-7kqrl3rv	656	25	cell	cell	NN
cord-347298-7kqrl3rv	656	26	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	656	27	under	under	IN
cord-347298-7kqrl3rv	656	28	various	various	JJ
cord-347298-7kqrl3rv	656	29	conditions	condition	NNS
cord-347298-7kqrl3rv	656	30	(	(	-LRB-
cord-347298-7kqrl3rv	656	31	Kanzaki	Kanzaki	NNP
cord-347298-7kqrl3rv	656	32	and	and	CC
cord-347298-7kqrl3rv	656	33	Morris	Morris	NNP
cord-347298-7kqrl3rv	656	34	1998	1998	CD
cord-347298-7kqrl3rv	656	35	;	;	:
cord-347298-7kqrl3rv	656	36	Riccioli	Riccioli	NNP
cord-347298-7kqrl3rv	656	37	et	et	NNP
cord-347298-7kqrl3rv	656	38	al	al	NNP
cord-347298-7kqrl3rv	656	39	.	.	.
cord-347298-7kqrl3rv	656	40	2000	2000	CD
cord-347298-7kqrl3rv	656	41	)	)	-RRB-
cord-347298-7kqrl3rv	656	42	.	.	.
cord-347298-7kqrl3rv	657	1	These	these	DT
cord-347298-7kqrl3rv	657	2	disparate	disparate	JJ
cord-347298-7kqrl3rv	657	3	observations	observation	NNS
cord-347298-7kqrl3rv	657	4	are	be	VBP
cord-347298-7kqrl3rv	657	5	indicative	indicative	JJ
cord-347298-7kqrl3rv	657	6	of	of	IN
cord-347298-7kqrl3rv	657	7	a	a	DT
cord-347298-7kqrl3rv	657	8	complex	complex	JJ
cord-347298-7kqrl3rv	657	9	relationship	relationship	NN
cord-347298-7kqrl3rv	657	10	between	between	IN
cord-347298-7kqrl3rv	657	11	IFN	IFN	NNP
cord-347298-7kqrl3rv	657	12	,	,	,
cord-347298-7kqrl3rv	657	13	the	the	DT
cord-347298-7kqrl3rv	657	14	local	local	JJ
cord-347298-7kqrl3rv	657	15	immune	immune	JJ
cord-347298-7kqrl3rv	657	16	system	system	NN
cord-347298-7kqrl3rv	657	17	,	,	,
cord-347298-7kqrl3rv	657	18	and	and	CC
cord-347298-7kqrl3rv	657	19	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	657	20	.	.	.
cord-347298-7kqrl3rv	658	1	IFN	IFN	NNP
cord-347298-7kqrl3rv	658	2	production	production	NN
cord-347298-7kqrl3rv	658	3	also	also	RB
cord-347298-7kqrl3rv	658	4	affects	affect	VBZ
cord-347298-7kqrl3rv	658	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	658	6	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	658	7	.	.	.
cord-347298-7kqrl3rv	659	1	Normal	normal	JJ
cord-347298-7kqrl3rv	659	2	healthy	healthy	JJ
cord-347298-7kqrl3rv	659	3	men	man	NNS
cord-347298-7kqrl3rv	659	4	treated	treat	VBN
cord-347298-7kqrl3rv	659	5	with	with	IN
cord-347298-7kqrl3rv	659	6	human	human	JJ
cord-347298-7kqrl3rv	659	7	IFN	IFN	NNP
cord-347298-7kqrl3rv	659	8	had	have	VBD
cord-347298-7kqrl3rv	659	9	significantly	significantly	RB
cord-347298-7kqrl3rv	659	10	decreased	decrease	VBN
cord-347298-7kqrl3rv	659	11	serum	serum	NN
cord-347298-7kqrl3rv	659	12	testosterone	testosterone	NN
cord-347298-7kqrl3rv	659	13	levels	level	NNS
cord-347298-7kqrl3rv	659	14	in	in	IN
cord-347298-7kqrl3rv	659	15	conjunction	conjunction	NN
cord-347298-7kqrl3rv	659	16	with	with	IN
cord-347298-7kqrl3rv	659	17	normal	normal	JJ
cord-347298-7kqrl3rv	659	18	serum	serum	NN
cord-347298-7kqrl3rv	659	19	gonadotropins	gonadotropin	NNS
cord-347298-7kqrl3rv	659	20	,	,	,
cord-347298-7kqrl3rv	659	21	and	and	CC
cord-347298-7kqrl3rv	659	22	both	both	CC
cord-347298-7kqrl3rv	659	23	IFN	IFN	NNP
cord-347298-7kqrl3rv	659	24	and	and	CC
cord-347298-7kqrl3rv	659	25	IFN	IFN	NNP
cord-347298-7kqrl3rv	659	26	inhibit	inhibit	VBP
cord-347298-7kqrl3rv	659	27	testosterone	testosterone	NN
cord-347298-7kqrl3rv	659	28	production	production	NN
cord-347298-7kqrl3rv	659	29	in	in	IN
cord-347298-7kqrl3rv	659	30	primary	primary	JJ
cord-347298-7kqrl3rv	659	31	cultures	culture	NNS
cord-347298-7kqrl3rv	659	32	of	of	IN
cord-347298-7kqrl3rv	659	33	Leydig	leydig	NN
cord-347298-7kqrl3rv	659	34	cells	cell	NNS
cord-347298-7kqrl3rv	659	35	(	(	-LRB-
cord-347298-7kqrl3rv	659	36	Orava	Orava	NNP
cord-347298-7kqrl3rv	659	37	et	et	FW
cord-347298-7kqrl3rv	659	38	al	al	NNP
cord-347298-7kqrl3rv	659	39	.	.	NNP
cord-347298-7kqrl3rv	659	40	1986	1986	CD
cord-347298-7kqrl3rv	659	41	)	)	-RRB-
cord-347298-7kqrl3rv	659	42	.	.	.
cord-347298-7kqrl3rv	660	1	Studies	study	NNS
cord-347298-7kqrl3rv	660	2	using	use	VBG
cord-347298-7kqrl3rv	660	3	porcine	porcine	JJ
cord-347298-7kqrl3rv	660	4	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	660	5	cells	cell	NNS
cord-347298-7kqrl3rv	660	6	indicate	indicate	VBP
cord-347298-7kqrl3rv	660	7	that	that	IN
cord-347298-7kqrl3rv	660	8	IFN	IFN	NNP
cord-347298-7kqrl3rv	660	9	exerts	exert	VBZ
cord-347298-7kqrl3rv	660	10	its	-PRON-	PRP$
cord-347298-7kqrl3rv	660	11	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	660	12	effect	effect	NN
cord-347298-7kqrl3rv	660	13	on	on	IN
cord-347298-7kqrl3rv	660	14	testosterone	testosterone	NN
cord-347298-7kqrl3rv	660	15	production	production	NN
cord-347298-7kqrl3rv	660	16	at	at	IN
cord-347298-7kqrl3rv	660	17	the	the	DT
cord-347298-7kqrl3rv	660	18	level	level	NN
cord-347298-7kqrl3rv	660	19	of	of	IN
cord-347298-7kqrl3rv	660	20	cholesterol	cholesterol	NN
cord-347298-7kqrl3rv	660	21	transport	transport	NN
cord-347298-7kqrl3rv	660	22	into	into	IN
cord-347298-7kqrl3rv	660	23	the	the	DT
cord-347298-7kqrl3rv	660	24	mitochondria	mitochondrion	NNS
cord-347298-7kqrl3rv	660	25	,	,	,
cord-347298-7kqrl3rv	660	26	and	and	CC
cord-347298-7kqrl3rv	660	27	inhibits	inhibit	VBZ
cord-347298-7kqrl3rv	660	28	expression	expression	NN
cord-347298-7kqrl3rv	660	29	of	of	IN
cord-347298-7kqrl3rv	660	30	the	the	DT
cord-347298-7kqrl3rv	660	31	steroidogenic	steroidogenic	NNP
cord-347298-7kqrl3rv	660	32	acute	acute	NNP
cord-347298-7kqrl3rv	660	33	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	660	34	(	(	-LRB-
cord-347298-7kqrl3rv	660	35	StAR	StAR	NNP
cord-347298-7kqrl3rv	660	36	)	)	-RRB-
cord-347298-7kqrl3rv	660	37	protein	protein	NN
cord-347298-7kqrl3rv	660	38	and	and	CC
cord-347298-7kqrl3rv	660	39	the	the	DT
cord-347298-7kqrl3rv	660	40	P-450	p-450	XX
cord-347298-7kqrl3rv	660	41	steroidogenic	steroidogenic	NNP
cord-347298-7kqrl3rv	660	42	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	660	43	,	,	,
cord-347298-7kqrl3rv	660	44	cholesterol	cholesterol	NN
cord-347298-7kqrl3rv	660	45	side	side	NN
cord-347298-7kqrl3rv	660	46	-	-	HYPH
cord-347298-7kqrl3rv	660	47	chain	chain	NN
cord-347298-7kqrl3rv	660	48	cleavage	cleavage	NN
cord-347298-7kqrl3rv	660	49	complex	complex	NN
cord-347298-7kqrl3rv	660	50	(	(	-LRB-
cord-347298-7kqrl3rv	660	51	P450scc	P450scc	NNS
cord-347298-7kqrl3rv	660	52	)	)	-RRB-
cord-347298-7kqrl3rv	660	53	and	and	CC
cord-347298-7kqrl3rv	660	54	17-hydroxylase	17-hydroxylase	CD
cord-347298-7kqrl3rv	660	55	/	/	SYM
cord-347298-7kqrl3rv	660	56	C17-C20	c17-c20	JJ
cord-347298-7kqrl3rv	660	57	lyase	lyase	NN
cord-347298-7kqrl3rv	660	58	(	(	-LRB-
cord-347298-7kqrl3rv	660	59	P450c17	p450c17	NN
cord-347298-7kqrl3rv	660	60	)	)	-RRB-
cord-347298-7kqrl3rv	661	1	(	(	-LRB-
cord-347298-7kqrl3rv	661	2	Orava	Orava	NNP
cord-347298-7kqrl3rv	661	3	et	et	FW
cord-347298-7kqrl3rv	661	4	al	al	NNP
cord-347298-7kqrl3rv	661	5	.	.	.
cord-347298-7kqrl3rv	662	1	1985	1985	CD
cord-347298-7kqrl3rv	663	1	(	(	-LRB-
cord-347298-7kqrl3rv	663	2	Orava	Orava	NNP
cord-347298-7kqrl3rv	663	3	et	et	FW
cord-347298-7kqrl3rv	663	4	al	al	NNP
cord-347298-7kqrl3rv	663	5	.	.	NNP
cord-347298-7kqrl3rv	663	6	,	,	,
cord-347298-7kqrl3rv	663	7	1989	1989	CD
cord-347298-7kqrl3rv	663	8	.	.	.
cord-347298-7kqrl3rv	664	1	These	these	DT
cord-347298-7kqrl3rv	664	2	data	datum	NNS
cord-347298-7kqrl3rv	664	3	indicate	indicate	VBP
cord-347298-7kqrl3rv	664	4	that	that	IN
cord-347298-7kqrl3rv	664	5	IFNs	ifn	NNS
cord-347298-7kqrl3rv	664	6	may	may	MD
cord-347298-7kqrl3rv	664	7	contribute	contribute	VB
cord-347298-7kqrl3rv	664	8	to	to	IN
cord-347298-7kqrl3rv	664	9	the	the	DT
cord-347298-7kqrl3rv	664	10	decline	decline	NN
cord-347298-7kqrl3rv	664	11	in	in	IN
cord-347298-7kqrl3rv	664	12	steroidogenic	steroidogenic	NNP
cord-347298-7kqrl3rv	664	13	function	function	NN
cord-347298-7kqrl3rv	664	14	of	of	IN
cord-347298-7kqrl3rv	664	15	patients	patient	NNS
cord-347298-7kqrl3rv	664	16	with	with	IN
cord-347298-7kqrl3rv	664	17	viral	viral	JJ
cord-347298-7kqrl3rv	664	18	infections	infection	NNS
cord-347298-7kqrl3rv	664	19	,	,	,
cord-347298-7kqrl3rv	664	20	in	in	IN
cord-347298-7kqrl3rv	664	21	particular	particular	JJ
cord-347298-7kqrl3rv	664	22	.	.	.
cord-347298-7kqrl3rv	665	1	However	however	RB
cord-347298-7kqrl3rv	665	2	,	,	,
cord-347298-7kqrl3rv	665	3	Dejucq	Dejucq	NNP
cord-347298-7kqrl3rv	665	4	et	et	NNP
cord-347298-7kqrl3rv	665	5	al	al	NNP
cord-347298-7kqrl3rv	665	6	.	.	.
cord-347298-7kqrl3rv	666	1	(	(	-LRB-
cord-347298-7kqrl3rv	666	2	1995	1995	CD
cord-347298-7kqrl3rv	666	3	Dejucq	Dejucq	NNP
cord-347298-7kqrl3rv	666	4	et	et	NNP
cord-347298-7kqrl3rv	666	5	al	al	NNP
cord-347298-7kqrl3rv	666	6	.	.	.
cord-347298-7kqrl3rv	667	1	(	(	-LRB-
cord-347298-7kqrl3rv	667	2	,	,	,
cord-347298-7kqrl3rv	667	3	1998a	1998a	CD
cord-347298-7kqrl3rv	667	4	have	have	VBP
cord-347298-7kqrl3rv	667	5	shown	show	VBN
cord-347298-7kqrl3rv	667	6	that	that	IN
cord-347298-7kqrl3rv	667	7	an	an	DT
cord-347298-7kqrl3rv	667	8	increase	increase	NN
cord-347298-7kqrl3rv	667	9	in	in	IN
cord-347298-7kqrl3rv	667	10	IFN	IFN	NNP
cord-347298-7kqrl3rv	667	11	and	and	CC
cord-347298-7kqrl3rv	667	12	IFN	IFN	NNP
cord-347298-7kqrl3rv	667	13	expression	expression	NN
cord-347298-7kqrl3rv	667	14	in	in	IN
cord-347298-7kqrl3rv	667	15	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	667	16	and	and	CC
cord-347298-7kqrl3rv	667	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	667	18	cells	cell	NNS
cord-347298-7kqrl3rv	667	19	of	of	IN
cord-347298-7kqrl3rv	667	20	rats	rat	NNS
cord-347298-7kqrl3rv	667	21	infected	infect	VBN
cord-347298-7kqrl3rv	667	22	with	with	IN
cord-347298-7kqrl3rv	667	23	Sendai	Sendai	NNP
cord-347298-7kqrl3rv	667	24	virus	virus	NN
cord-347298-7kqrl3rv	667	25	was	be	VBD
cord-347298-7kqrl3rv	667	26	actually	actually	RB
cord-347298-7kqrl3rv	667	27	associated	associate	VBN
cord-347298-7kqrl3rv	667	28	with	with	IN
cord-347298-7kqrl3rv	667	29	an	an	DT
cord-347298-7kqrl3rv	667	30	increase	increase	NN
cord-347298-7kqrl3rv	667	31	in	in	IN
cord-347298-7kqrl3rv	667	32	testosterone	testosterone	NN
cord-347298-7kqrl3rv	667	33	production	production	NN
cord-347298-7kqrl3rv	667	34	.	.	.
cord-347298-7kqrl3rv	668	1	These	these	DT
cord-347298-7kqrl3rv	668	2	results	result	NNS
cord-347298-7kqrl3rv	668	3	suggest	suggest	VBP
cord-347298-7kqrl3rv	668	4	that	that	IN
cord-347298-7kqrl3rv	668	5	indirect	indirect	JJ
cord-347298-7kqrl3rv	668	6	or	or	CC
cord-347298-7kqrl3rv	668	7	secondary	secondary	JJ
cord-347298-7kqrl3rv	668	8	stimulatory	stimulatory	JJ
cord-347298-7kqrl3rv	668	9	effects	effect	NNS
cord-347298-7kqrl3rv	668	10	on	on	IN
cord-347298-7kqrl3rv	668	11	testicular	testicular	JJ
cord-347298-7kqrl3rv	668	12	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	668	13	may	may	MD
cord-347298-7kqrl3rv	668	14	be	be	VB
cord-347298-7kqrl3rv	668	15	involved	involve	VBN
cord-347298-7kqrl3rv	668	16	,	,	,
cord-347298-7kqrl3rv	668	17	providing	provide	VBG
cord-347298-7kqrl3rv	668	18	further	further	JJ
cord-347298-7kqrl3rv	668	19	evidence	evidence	NN
cord-347298-7kqrl3rv	668	20	that	that	IN
cord-347298-7kqrl3rv	668	21	IFNs	ifn	NNS
cord-347298-7kqrl3rv	668	22	play	play	VB
cord-347298-7kqrl3rv	668	23	a	a	DT
cord-347298-7kqrl3rv	668	24	complex	complex	JJ
cord-347298-7kqrl3rv	668	25	role	role	NN
cord-347298-7kqrl3rv	668	26	in	in	IN
cord-347298-7kqrl3rv	668	27	testicular	testicular	JJ
cord-347298-7kqrl3rv	668	28	function	function	NN
cord-347298-7kqrl3rv	668	29	.	.	.
cord-347298-7kqrl3rv	669	1	and	and	CC
cord-347298-7kqrl3rv	669	2	activin	activin	NNP
cord-347298-7kqrl3rv	670	1	A	a	DT
cord-347298-7kqrl3rv	670	2	The	the	DT
cord-347298-7kqrl3rv	670	3	three	three	CD
cord-347298-7kqrl3rv	670	4	TGF	TGF	NNP
cord-347298-7kqrl3rv	670	5	family	family	NN
cord-347298-7kqrl3rv	670	6	members	member	NNS
cord-347298-7kqrl3rv	670	7	that	that	WDT
cord-347298-7kqrl3rv	670	8	are	be	VBP
cord-347298-7kqrl3rv	670	9	expressed	express	VBN
cord-347298-7kqrl3rv	670	10	in	in	IN
cord-347298-7kqrl3rv	670	11	mammals	mammal	NNS
cord-347298-7kqrl3rv	670	12	(	(	-LRB-
cord-347298-7kqrl3rv	670	13	TGF	TGF	NNP
cord-347298-7kqrl3rv	670	14	1	1	CD
cord-347298-7kqrl3rv	670	15	,	,	,
cord-347298-7kqrl3rv	670	16	TGF	TGF	NNP
cord-347298-7kqrl3rv	670	17	2	2	CD
cord-347298-7kqrl3rv	670	18	,	,	,
cord-347298-7kqrl3rv	670	19	and	and	CC
cord-347298-7kqrl3rv	670	20	TGF	TGF	NNP
cord-347298-7kqrl3rv	670	21	3	3	CD
cord-347298-7kqrl3rv	670	22	)	)	-RRB-
cord-347298-7kqrl3rv	670	23	are	be	VBP
cord-347298-7kqrl3rv	670	24	the	the	DT
cord-347298-7kqrl3rv	670	25	archetypes	archetype	NNS
cord-347298-7kqrl3rv	670	26	of	of	IN
cord-347298-7kqrl3rv	670	27	a	a	DT
cord-347298-7kqrl3rv	670	28	much	much	RB
cord-347298-7kqrl3rv	670	29	larger	large	JJR
cord-347298-7kqrl3rv	670	30	superfamily	superfamily	NN
cord-347298-7kqrl3rv	670	31	of	of	IN
cord-347298-7kqrl3rv	670	32	mostly	mostly	RB
cord-347298-7kqrl3rv	670	33	homo	homo	NN
cord-347298-7kqrl3rv	670	34	-	-	HYPH
cord-347298-7kqrl3rv	670	35	and	and	CC
cord-347298-7kqrl3rv	670	36	heterodimeric	heterodimeric	JJ
cord-347298-7kqrl3rv	670	37	proteins	protein	NNS
cord-347298-7kqrl3rv	670	38	,	,	,
cord-347298-7kqrl3rv	670	39	which	which	WDT
cord-347298-7kqrl3rv	670	40	includes	include	VBZ
cord-347298-7kqrl3rv	670	41	the	the	DT
cord-347298-7kqrl3rv	670	42	activins	activin	NNS
cord-347298-7kqrl3rv	670	43	,	,	,
cord-347298-7kqrl3rv	670	44	the	the	DT
cord-347298-7kqrl3rv	670	45	bone	bone	NN
cord-347298-7kqrl3rv	670	46	morphogenetic	morphogenetic	JJ
cord-347298-7kqrl3rv	670	47	proteins	protein	NNS
cord-347298-7kqrl3rv	670	48	(	(	-LRB-
cord-347298-7kqrl3rv	670	49	BMPs	BMPs	NNP
cord-347298-7kqrl3rv	670	50	)	)	-RRB-
cord-347298-7kqrl3rv	670	51	,	,	,
cord-347298-7kqrl3rv	670	52	inhibin	inhibin	NNP
cord-347298-7kqrl3rv	670	53	,	,	,
cord-347298-7kqrl3rv	670	54	and	and	CC
cord-347298-7kqrl3rv	670	55	anti	anti	JJ
cord-347298-7kqrl3rv	670	56	-	-	JJ
cord-347298-7kqrl3rv	670	57	Müllerian	müllerian	JJ
cord-347298-7kqrl3rv	670	58	hormone	hormone	NN
cord-347298-7kqrl3rv	670	59	(	(	-LRB-
cord-347298-7kqrl3rv	670	60	Lin	Lin	NNP
cord-347298-7kqrl3rv	670	61	et	et	NNP
cord-347298-7kqrl3rv	670	62	al	al	NNP
cord-347298-7kqrl3rv	670	63	.	.	.
cord-347298-7kqrl3rv	670	64	2006	2006	CD
cord-347298-7kqrl3rv	670	65	)	)	-RRB-
cord-347298-7kqrl3rv	670	66	.	.	.
cord-347298-7kqrl3rv	671	1	The	the	DT
cord-347298-7kqrl3rv	671	2	TGFs	tgf	NNS
cord-347298-7kqrl3rv	671	3	themselves	-PRON-	PRP
cord-347298-7kqrl3rv	671	4	are	be	VBP
cord-347298-7kqrl3rv	671	5	multifunctional	multifunctional	JJ
cord-347298-7kqrl3rv	671	6	growth	growth	NN
cord-347298-7kqrl3rv	671	7	and	and	CC
cord-347298-7kqrl3rv	671	8	differentiation	differentiation	NN
cord-347298-7kqrl3rv	671	9	factors	factor	NNS
cord-347298-7kqrl3rv	671	10	involved	involve	VBN
cord-347298-7kqrl3rv	671	11	in	in	IN
cord-347298-7kqrl3rv	671	12	many	many	JJ
cord-347298-7kqrl3rv	671	13	aspects	aspect	NNS
cord-347298-7kqrl3rv	671	14	of	of	IN
cord-347298-7kqrl3rv	671	15	tissue	tissue	NN
cord-347298-7kqrl3rv	671	16	remodeling	remodeling	NN
cord-347298-7kqrl3rv	671	17	and	and	CC
cord-347298-7kqrl3rv	671	18	repair	repair	NN
cord-347298-7kqrl3rv	671	19	as	as	RB
cord-347298-7kqrl3rv	671	20	well	well	RB
cord-347298-7kqrl3rv	671	21	as	as	IN
cord-347298-7kqrl3rv	671	22	regulation	regulation	NN
cord-347298-7kqrl3rv	671	23	of	of	IN
cord-347298-7kqrl3rv	671	24	the	the	DT
cord-347298-7kqrl3rv	671	25	immune	immune	JJ
cord-347298-7kqrl3rv	671	26	system	system	NN
cord-347298-7kqrl3rv	671	27	(	(	-LRB-
cord-347298-7kqrl3rv	671	28	Ashcroft	Ashcroft	NNP
cord-347298-7kqrl3rv	671	29	1999	1999	CD
cord-347298-7kqrl3rv	671	30	;	;	:
cord-347298-7kqrl3rv	672	1	Chang	Chang	NNP
cord-347298-7kqrl3rv	672	2	et	et	NNP
cord-347298-7kqrl3rv	672	3	al	al	NNP
cord-347298-7kqrl3rv	672	4	.	.	.
cord-347298-7kqrl3rv	673	1	2001	2001	CD
cord-347298-7kqrl3rv	673	2	;	;	:
cord-347298-7kqrl3rv	673	3	Licona	Licona	NNP
cord-347298-7kqrl3rv	673	4	-	-	HYPH
cord-347298-7kqrl3rv	673	5	Limón	Limón	NNP
cord-347298-7kqrl3rv	673	6	and	and	CC
cord-347298-7kqrl3rv	673	7	Soldevila	Soldevila	NNP
cord-347298-7kqrl3rv	673	8	2007	2007	CD
cord-347298-7kqrl3rv	673	9	)	)	-RRB-
cord-347298-7kqrl3rv	673	10	.	.	.
cord-347298-7kqrl3rv	674	1	Nearly	nearly	RB
cord-347298-7kqrl3rv	674	2	all	all	DT
cord-347298-7kqrl3rv	674	3	cells	cell	NNS
cord-347298-7kqrl3rv	674	4	synthesize	synthesize	VBP
cord-347298-7kqrl3rv	674	5	a	a	DT
cord-347298-7kqrl3rv	674	6	form	form	NN
cord-347298-7kqrl3rv	674	7	of	of	IN
cord-347298-7kqrl3rv	674	8	TGF	TGF	NNP
cord-347298-7kqrl3rv	674	9	and	and	CC
cord-347298-7kqrl3rv	674	10	possess	possess	VB
cord-347298-7kqrl3rv	674	11	functional	functional	JJ
cord-347298-7kqrl3rv	674	12	receptors	receptor	NNS
cord-347298-7kqrl3rv	674	13	for	for	IN
cord-347298-7kqrl3rv	674	14	these	these	DT
cord-347298-7kqrl3rv	674	15	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	674	16	.	.	.
cord-347298-7kqrl3rv	675	1	Most	Most	JJS
cord-347298-7kqrl3rv	675	2	TGF	TGF	NNP
cord-347298-7kqrl3rv	675	3	family	family	NN
cord-347298-7kqrl3rv	675	4	ligands	ligand	NNS
cord-347298-7kqrl3rv	675	5	act	act	VBP
cord-347298-7kqrl3rv	675	6	via	via	IN
cord-347298-7kqrl3rv	675	7	dual	dual	JJ
cord-347298-7kqrl3rv	675	8	transmembrane	transmembrane	NN
cord-347298-7kqrl3rv	675	9	serine	serine	NN
cord-347298-7kqrl3rv	675	10	/	/	SYM
cord-347298-7kqrl3rv	675	11	threonine	threonine	NN
cord-347298-7kqrl3rv	675	12	kinase	kinase	NN
cord-347298-7kqrl3rv	675	13	receptors	receptor	NNS
cord-347298-7kqrl3rv	675	14	,	,	,
cord-347298-7kqrl3rv	675	15	called	call	VBN
cord-347298-7kqrl3rv	675	16	type	type	NN
cord-347298-7kqrl3rv	675	17	I	-PRON-	PRP
cord-347298-7kqrl3rv	675	18	and	and	CC
cord-347298-7kqrl3rv	675	19	type	type	NN
cord-347298-7kqrl3rv	675	20	II	II	NNP
cord-347298-7kqrl3rv	675	21	,	,	,
cord-347298-7kqrl3rv	675	22	which	which	WDT
cord-347298-7kqrl3rv	675	23	interact	interact	VBP
cord-347298-7kqrl3rv	675	24	upon	upon	IN
cord-347298-7kqrl3rv	675	25	ligand	ligand	NN
cord-347298-7kqrl3rv	675	26	binding	binding	NN
cord-347298-7kqrl3rv	675	27	(	(	-LRB-
cord-347298-7kqrl3rv	675	28	Cárcamo	Cárcamo	NNP
cord-347298-7kqrl3rv	675	29	et	et	NNP
cord-347298-7kqrl3rv	675	30	al	al	NNP
cord-347298-7kqrl3rv	675	31	.	.	.
cord-347298-7kqrl3rv	675	32	1994	1994	CD
cord-347298-7kqrl3rv	675	33	;	;	.
cord-347298-7kqrl3rv	676	1	Ebner	Ebner	NNP
cord-347298-7kqrl3rv	676	2	et	et	NNP
cord-347298-7kqrl3rv	676	3	al	al	NNP
cord-347298-7kqrl3rv	676	4	.	.	.
cord-347298-7kqrl3rv	676	5	1993	1993	CD
cord-347298-7kqrl3rv	677	1	;	;	:
cord-347298-7kqrl3rv	677	2	Massagué	Massagué	NNP
cord-347298-7kqrl3rv	677	3	et	et	NNP
cord-347298-7kqrl3rv	677	4	al	al	NNP
cord-347298-7kqrl3rv	677	5	.	.	NNP
cord-347298-7kqrl3rv	677	6	1992	1992	CD
cord-347298-7kqrl3rv	677	7	)	)	-RRB-
cord-347298-7kqrl3rv	677	8	.	.	.
cord-347298-7kqrl3rv	678	1	Signals	signal	NNS
cord-347298-7kqrl3rv	678	2	are	be	VBP
cord-347298-7kqrl3rv	678	3	transduced	transduce	VBN
cord-347298-7kqrl3rv	678	4	from	from	IN
cord-347298-7kqrl3rv	678	5	the	the	DT
cord-347298-7kqrl3rv	678	6	membrane	membrane	NN
cord-347298-7kqrl3rv	678	7	to	to	IN
cord-347298-7kqrl3rv	678	8	the	the	DT
cord-347298-7kqrl3rv	678	9	nucleus	nucleus	NN
cord-347298-7kqrl3rv	678	10	through	through	IN
cord-347298-7kqrl3rv	678	11	phosphorylation	phosphorylation	NN
cord-347298-7kqrl3rv	678	12	of	of	IN
cord-347298-7kqrl3rv	678	13	the	the	DT
cord-347298-7kqrl3rv	678	14	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	678	15	Smad	Smad	NNP
cord-347298-7kqrl3rv	678	16	signaling	signal	VBG
cord-347298-7kqrl3rv	678	17	proteins	protein	NNS
cord-347298-7kqrl3rv	678	18	,	,	,
cord-347298-7kqrl3rv	678	19	with	with	IN
cord-347298-7kqrl3rv	678	20	Smads	Smads	NNP
cord-347298-7kqrl3rv	678	21	2	2	CD
cord-347298-7kqrl3rv	678	22	,	,	,
cord-347298-7kqrl3rv	678	23	3	3	CD
cord-347298-7kqrl3rv	678	24	,	,	,
cord-347298-7kqrl3rv	678	25	and	and	CC
cord-347298-7kqrl3rv	678	26	4	4	CD
cord-347298-7kqrl3rv	678	27	responsible	responsible	JJ
cord-347298-7kqrl3rv	678	28	for	for	IN
cord-347298-7kqrl3rv	678	29	mediating	mediate	VBG
cord-347298-7kqrl3rv	678	30	TGF	TGF	NNP
cord-347298-7kqrl3rv	678	31	and	and	CC
cord-347298-7kqrl3rv	678	32	activin	activin	NNP
cord-347298-7kqrl3rv	678	33	signaling	signal	VBG
cord-347298-7kqrl3rv	679	1	(	(	-LRB-
cord-347298-7kqrl3rv	679	2	Datto	Datto	NNP
cord-347298-7kqrl3rv	679	3	et	et	NNP
cord-347298-7kqrl3rv	679	4	al	al	NNP
cord-347298-7kqrl3rv	679	5	.	.	.
cord-347298-7kqrl3rv	679	6	1999	1999	CD
cord-347298-7kqrl3rv	679	7	;	;	:
cord-347298-7kqrl3rv	679	8	de	de	NNP
cord-347298-7kqrl3rv	679	9	Caestecker	Caestecker	NNP
cord-347298-7kqrl3rv	679	10	et	et	NNP
cord-347298-7kqrl3rv	679	11	al	al	NNP
cord-347298-7kqrl3rv	679	12	.	.	NNP
cord-347298-7kqrl3rv	679	13	1998	1998	CD
cord-347298-7kqrl3rv	679	14	)	)	-RRB-
cord-347298-7kqrl3rv	679	15	.	.	.
cord-347298-7kqrl3rv	680	1	All	all	DT
cord-347298-7kqrl3rv	680	2	three	three	CD
cord-347298-7kqrl3rv	680	3	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	680	4	TGF	TGF	NNP
cord-347298-7kqrl3rv	680	5	forms	form	NNS
cord-347298-7kqrl3rv	680	6	are	be	VBP
cord-347298-7kqrl3rv	680	7	differentially	differentially	RB
cord-347298-7kqrl3rv	680	8	expressed	express	VBN
cord-347298-7kqrl3rv	680	9	by	by	IN
cord-347298-7kqrl3rv	680	10	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	680	11	cells	cell	NNS
cord-347298-7kqrl3rv	680	12	,	,	,
cord-347298-7kqrl3rv	680	13	peritubular	peritubular	NNP
cord-347298-7kqrl3rv	680	14	cells	cell	NNS
cord-347298-7kqrl3rv	680	15	,	,	,
cord-347298-7kqrl3rv	680	16	and	and	CC
cord-347298-7kqrl3rv	680	17	Leydig	leydig	NN
cord-347298-7kqrl3rv	680	18	cells	cell	NNS
cord-347298-7kqrl3rv	680	19	in	in	IN
cord-347298-7kqrl3rv	680	20	the	the	DT
cord-347298-7kqrl3rv	680	21	fetal	fetal	JJ
cord-347298-7kqrl3rv	680	22	and	and	CC
cord-347298-7kqrl3rv	680	23	immature	immature	JJ
cord-347298-7kqrl3rv	680	24	testis	testis	NN
cord-347298-7kqrl3rv	680	25	,	,	,
cord-347298-7kqrl3rv	680	26	but	but	CC
cord-347298-7kqrl3rv	680	27	production	production	NN
cord-347298-7kqrl3rv	680	28	declines	decline	VBZ
cord-347298-7kqrl3rv	680	29	considerably	considerably	RB
cord-347298-7kqrl3rv	680	30	during	during	IN
cord-347298-7kqrl3rv	680	31	sexual	sexual	JJ
cord-347298-7kqrl3rv	680	32	maturation	maturation	NN
cord-347298-7kqrl3rv	680	33	Gautier	Gautier	NNP
cord-347298-7kqrl3rv	680	34	et	et	FW
cord-347298-7kqrl3rv	680	35	al	al	NNP
cord-347298-7kqrl3rv	680	36	.	.	.
cord-347298-7kqrl3rv	680	37	1994	1994	CD
cord-347298-7kqrl3rv	680	38	;	;	:
cord-347298-7kqrl3rv	680	39	Mullaney	Mullaney	NNP
cord-347298-7kqrl3rv	680	40	and	and	CC
cord-347298-7kqrl3rv	680	41	Skinner	Skinner	NNP
cord-347298-7kqrl3rv	680	42	1993	1993	CD
cord-347298-7kqrl3rv	680	43	;	;	:
cord-347298-7kqrl3rv	680	44	Olaso	Olaso	NNP
cord-347298-7kqrl3rv	680	45	et	et	FW
cord-347298-7kqrl3rv	680	46	al	al	NNP
cord-347298-7kqrl3rv	680	47	.	.	.
cord-347298-7kqrl3rv	680	48	1997	1997	CD
cord-347298-7kqrl3rv	680	49	)	)	-RRB-
cord-347298-7kqrl3rv	680	50	.	.	.
cord-347298-7kqrl3rv	681	1	In	in	IN
cord-347298-7kqrl3rv	681	2	the	the	DT
cord-347298-7kqrl3rv	681	3	postpubertal	postpubertal	JJ
cord-347298-7kqrl3rv	681	4	testis	testis	NN
cord-347298-7kqrl3rv	681	5	,	,	,
cord-347298-7kqrl3rv	681	6	they	-PRON-	PRP
cord-347298-7kqrl3rv	681	7	have	have	VBP
cord-347298-7kqrl3rv	681	8	also	also	RB
cord-347298-7kqrl3rv	681	9	been	be	VBN
cord-347298-7kqrl3rv	681	10	localized	localize	VBN
cord-347298-7kqrl3rv	681	11	to	to	IN
cord-347298-7kqrl3rv	681	12	the	the	DT
cord-347298-7kqrl3rv	681	13	germ	germ	NN
cord-347298-7kqrl3rv	681	14	cells	cell	NNS
cord-347298-7kqrl3rv	681	15	(	(	-LRB-
cord-347298-7kqrl3rv	681	16	Caussanel	Caussanel	NNP
cord-347298-7kqrl3rv	681	17	et	et	NNP
cord-347298-7kqrl3rv	681	18	al	al	NNP
cord-347298-7kqrl3rv	681	19	.	.	.
cord-347298-7kqrl3rv	681	20	1997	1997	CD
cord-347298-7kqrl3rv	681	21	;	;	:
cord-347298-7kqrl3rv	681	22	Teerds	Teerds	NNP
cord-347298-7kqrl3rv	681	23	and	and	CC
cord-347298-7kqrl3rv	681	24	Dorrington	Dorrington	NNP
cord-347298-7kqrl3rv	681	25	1993	1993	CD
cord-347298-7kqrl3rv	681	26	)	)	-RRB-
cord-347298-7kqrl3rv	681	27	,	,	,
cord-347298-7kqrl3rv	681	28	and	and	CC
cord-347298-7kqrl3rv	681	29	TGF	TGF	NNP
cord-347298-7kqrl3rv	681	30	receptors	receptor	NNS
cord-347298-7kqrl3rv	681	31	are	be	VBP
cord-347298-7kqrl3rv	681	32	found	find	VBN
cord-347298-7kqrl3rv	681	33	in	in	IN
cord-347298-7kqrl3rv	681	34	both	both	DT
cord-347298-7kqrl3rv	681	35	somatic	somatic	JJ
cord-347298-7kqrl3rv	681	36	and	and	CC
cord-347298-7kqrl3rv	681	37	germ	germ	NN
cord-347298-7kqrl3rv	681	38	cells	cell	NNS
cord-347298-7kqrl3rv	681	39	(	(	-LRB-
cord-347298-7kqrl3rv	681	40	Caussanel	Caussanel	NNP
cord-347298-7kqrl3rv	681	41	et	et	NNP
cord-347298-7kqrl3rv	681	42	al	al	NNP
cord-347298-7kqrl3rv	681	43	.	.	.
cord-347298-7kqrl3rv	681	44	1997	1997	CD
cord-347298-7kqrl3rv	681	45	;	;	:
cord-347298-7kqrl3rv	681	46	Goddard	Goddard	NNP
cord-347298-7kqrl3rv	681	47	et	et	NNP
cord-347298-7kqrl3rv	681	48	al	al	NNP
cord-347298-7kqrl3rv	681	49	.	.	.
cord-347298-7kqrl3rv	681	50	2000	2000	CD
cord-347298-7kqrl3rv	681	51	;	;	:
cord-347298-7kqrl3rv	681	52	Le	Le	NNP
cord-347298-7kqrl3rv	681	53	Magueresse	Magueresse	NNP
cord-347298-7kqrl3rv	681	54	-	-	HYPH
cord-347298-7kqrl3rv	681	55	Battistoni	Battistoni	NNP
cord-347298-7kqrl3rv	681	56	et	et	NNP
cord-347298-7kqrl3rv	681	57	al	al	NNP
cord-347298-7kqrl3rv	681	58	.	.	NNP
cord-347298-7kqrl3rv	681	59	1995	1995	CD
cord-347298-7kqrl3rv	681	60	)	)	-RRB-
cord-347298-7kqrl3rv	681	61	.	.	.
cord-347298-7kqrl3rv	682	1	The	the	DT
cord-347298-7kqrl3rv	682	2	TGFs	tgf	NNS
cord-347298-7kqrl3rv	682	3	appear	appear	VBP
cord-347298-7kqrl3rv	682	4	to	to	TO
cord-347298-7kqrl3rv	682	5	be	be	VB
cord-347298-7kqrl3rv	682	6	involved	involve	VBN
cord-347298-7kqrl3rv	682	7	in	in	IN
cord-347298-7kqrl3rv	682	8	testicular	testicular	JJ
cord-347298-7kqrl3rv	682	9	development	development	NN
cord-347298-7kqrl3rv	682	10	by	by	IN
cord-347298-7kqrl3rv	682	11	controlling	control	VBG
cord-347298-7kqrl3rv	682	12	,	,	,
cord-347298-7kqrl3rv	682	13	among	among	IN
cord-347298-7kqrl3rv	682	14	other	other	JJ
cord-347298-7kqrl3rv	682	15	things	thing	NNS
cord-347298-7kqrl3rv	682	16	,	,	,
cord-347298-7kqrl3rv	682	17	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	682	18	of	of	IN
cord-347298-7kqrl3rv	682	19	undifferentiated	undifferentiated	JJ
cord-347298-7kqrl3rv	682	20	spermatogonia	spermatogonia	NNP
cord-347298-7kqrl3rv	682	21	(	(	-LRB-
cord-347298-7kqrl3rv	682	22	gonocytes	gonocytes	NNP
cord-347298-7kqrl3rv	682	23	)	)	-RRB-
cord-347298-7kqrl3rv	683	1	(	(	-LRB-
cord-347298-7kqrl3rv	683	2	Olaso	Olaso	NNP
cord-347298-7kqrl3rv	683	3	et	et	NNP
cord-347298-7kqrl3rv	683	4	al	al	NNP
cord-347298-7kqrl3rv	683	5	.	.	NNP
cord-347298-7kqrl3rv	683	6	1998	1998	CD
cord-347298-7kqrl3rv	683	7	)	)	-RRB-
cord-347298-7kqrl3rv	683	8	,	,	,
cord-347298-7kqrl3rv	683	9	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	683	10	tubule	tubule	NN
cord-347298-7kqrl3rv	683	11	formation	formation	NN
cord-347298-7kqrl3rv	683	12	,	,	,
cord-347298-7kqrl3rv	683	13	and	and	CC
cord-347298-7kqrl3rv	683	14	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	683	15	cell	cell	NN
cord-347298-7kqrl3rv	683	16	differentiation	differentiation	NN
cord-347298-7kqrl3rv	684	1	(	(	-LRB-
cord-347298-7kqrl3rv	684	2	Cupp	Cupp	NNP
cord-347298-7kqrl3rv	684	3	et	et	FW
cord-347298-7kqrl3rv	684	4	al	al	NNP
cord-347298-7kqrl3rv	684	5	.	.	.
cord-347298-7kqrl3rv	685	1	1999	1999	CD
cord-347298-7kqrl3rv	685	2	;	;	:
cord-347298-7kqrl3rv	685	3	Dickson	Dickson	NNP
cord-347298-7kqrl3rv	685	4	et	et	NNP
cord-347298-7kqrl3rv	685	5	al	al	NNP
cord-347298-7kqrl3rv	685	6	.	.	.
cord-347298-7kqrl3rv	686	1	2002	2002	CD
cord-347298-7kqrl3rv	686	2	;	;	:
cord-347298-7kqrl3rv	686	3	Khan	Khan	NNP
cord-347298-7kqrl3rv	686	4	et	et	NNP
cord-347298-7kqrl3rv	686	5	al	al	NNP
cord-347298-7kqrl3rv	686	6	.	.	.
cord-347298-7kqrl3rv	687	1	1992a	1992a	CD
cord-347298-7kqrl3rv	687	2	;	;	:
cord-347298-7kqrl3rv	687	3	Konrad	Konrad	NNP
cord-347298-7kqrl3rv	687	4	et	et	NNP
cord-347298-7kqrl3rv	687	5	al	al	NNP
cord-347298-7kqrl3rv	687	6	.	.	.
cord-347298-7kqrl3rv	687	7	2000	2000	CD
cord-347298-7kqrl3rv	687	8	)	)	-RRB-
cord-347298-7kqrl3rv	687	9	.	.	.
cord-347298-7kqrl3rv	688	1	In	in	IN
cord-347298-7kqrl3rv	688	2	the	the	DT
cord-347298-7kqrl3rv	688	3	adult	adult	NN
cord-347298-7kqrl3rv	688	4	testis	testis	NN
cord-347298-7kqrl3rv	688	5	,	,	,
cord-347298-7kqrl3rv	688	6	TGF	TGF	NNP
cord-347298-7kqrl3rv	688	7	2	2	CD
cord-347298-7kqrl3rv	688	8	and	and	CC
cord-347298-7kqrl3rv	688	9	TGF	TGF	NNP
cord-347298-7kqrl3rv	688	10	3	3	CD
cord-347298-7kqrl3rv	688	11	regulate	regulate	VBP
cord-347298-7kqrl3rv	688	12	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	688	13	cell	cell	NN
cord-347298-7kqrl3rv	688	14	tight	tight	JJ
cord-347298-7kqrl3rv	688	15	junction	junction	NN
cord-347298-7kqrl3rv	688	16	dynamics	dynamic	NNS
cord-347298-7kqrl3rv	688	17	,	,	,
cord-347298-7kqrl3rv	688	18	indicating	indicate	VBG
cord-347298-7kqrl3rv	688	19	a	a	DT
cord-347298-7kqrl3rv	688	20	role	role	NN
cord-347298-7kqrl3rv	688	21	in	in	IN
cord-347298-7kqrl3rv	688	22	regulating	regulate	VBG
cord-347298-7kqrl3rv	688	23	the	the	DT
cord-347298-7kqrl3rv	688	24	permeability	permeability	NN
cord-347298-7kqrl3rv	688	25	of	of	IN
cord-347298-7kqrl3rv	688	26	the	the	DT
cord-347298-7kqrl3rv	688	27	bloodtestis	bloodtestis	NNP
cord-347298-7kqrl3rv	688	28	barrier	barrier	NN
cord-347298-7kqrl3rv	688	29	to	to	TO
cord-347298-7kqrl3rv	688	30	facilitate	facilitate	VB
cord-347298-7kqrl3rv	688	31	the	the	DT
cord-347298-7kqrl3rv	688	32	passage	passage	NN
cord-347298-7kqrl3rv	688	33	of	of	IN
cord-347298-7kqrl3rv	688	34	spermatocytes	spermatocytes	NNPS
cord-347298-7kqrl3rv	688	35	across	across	IN
cord-347298-7kqrl3rv	688	36	the	the	DT
cord-347298-7kqrl3rv	688	37	barrier	barrier	NN
cord-347298-7kqrl3rv	688	38	during	during	IN
cord-347298-7kqrl3rv	688	39	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	688	40	(	(	-LRB-
cord-347298-7kqrl3rv	688	41	Lui	Lui	NNP
cord-347298-7kqrl3rv	688	42	et	et	FW
cord-347298-7kqrl3rv	688	43	al	al	NNP
cord-347298-7kqrl3rv	688	44	.	.	NNP
cord-347298-7kqrl3rv	688	45	2003	2003	CD
cord-347298-7kqrl3rv	688	46	;	;	:
cord-347298-7kqrl3rv	689	1	Xia	Xia	NNP
cord-347298-7kqrl3rv	689	2	et	et	NNP
cord-347298-7kqrl3rv	689	3	al	al	NNP
cord-347298-7kqrl3rv	689	4	.	.	.
cord-347298-7kqrl3rv	689	5	2006	2006	CD
cord-347298-7kqrl3rv	689	6	)	)	-RRB-
cord-347298-7kqrl3rv	689	7	.	.	.
cord-347298-7kqrl3rv	690	1	However	however	RB
cord-347298-7kqrl3rv	690	2	,	,	,
cord-347298-7kqrl3rv	690	3	the	the	DT
cord-347298-7kqrl3rv	690	4	TGFs	tgf	NNS
cord-347298-7kqrl3rv	690	5	are	be	VBP
cord-347298-7kqrl3rv	690	6	also	also	RB
cord-347298-7kqrl3rv	690	7	potent	potent	JJ
cord-347298-7kqrl3rv	690	8	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	690	9	of	of	IN
cord-347298-7kqrl3rv	690	10	the	the	DT
cord-347298-7kqrl3rv	690	11	activity	activity	NN
cord-347298-7kqrl3rv	690	12	of	of	IN
cord-347298-7kqrl3rv	690	13	immune	immune	JJ
cord-347298-7kqrl3rv	690	14	cells	cell	NNS
cord-347298-7kqrl3rv	690	15	,	,	,
cord-347298-7kqrl3rv	690	16	especially	especially	RB
cord-347298-7kqrl3rv	690	17	T	t	NN
cord-347298-7kqrl3rv	690	18	cells	cell	NNS
cord-347298-7kqrl3rv	690	19	,	,	,
cord-347298-7kqrl3rv	690	20	B	b	NN
cord-347298-7kqrl3rv	690	21	cells	cell	NNS
cord-347298-7kqrl3rv	690	22	,	,	,
cord-347298-7kqrl3rv	690	23	and	and	CC
cord-347298-7kqrl3rv	690	24	NK	NK	NNP
cord-347298-7kqrl3rv	690	25	cells	cell	NNS
cord-347298-7kqrl3rv	690	26	(	(	-LRB-
cord-347298-7kqrl3rv	690	27	Ahmad	Ahmad	NNP
cord-347298-7kqrl3rv	690	28	et	et	NNP
cord-347298-7kqrl3rv	690	29	al	al	NNP
cord-347298-7kqrl3rv	690	30	.	.	.
cord-347298-7kqrl3rv	690	31	1997	1997	CD
cord-347298-7kqrl3rv	690	32	;	;	.
cord-347298-7kqrl3rv	691	1	Ashcroft	Ashcroft	NNP
cord-347298-7kqrl3rv	691	2	1999	1999	CD
cord-347298-7kqrl3rv	691	3	;	;	:
cord-347298-7kqrl3rv	691	4	Cousins	Cousins	NNP
cord-347298-7kqrl3rv	691	5	et	et	NNP
cord-347298-7kqrl3rv	691	6	al	al	NNP
cord-347298-7kqrl3rv	691	7	.	.	.
cord-347298-7kqrl3rv	692	1	1991	1991	CD
cord-347298-7kqrl3rv	692	2	;	;	:
cord-347298-7kqrl3rv	692	3	Licona	Licona	NNP
cord-347298-7kqrl3rv	692	4	-	-	HYPH
cord-347298-7kqrl3rv	692	5	Limón	Limón	NNP
cord-347298-7kqrl3rv	692	6	and	and	CC
cord-347298-7kqrl3rv	692	7	Soldevila	Soldevila	NNP
cord-347298-7kqrl3rv	692	8	2007	2007	CD
cord-347298-7kqrl3rv	692	9	;	;	:
cord-347298-7kqrl3rv	692	10	Wahl	Wahl	NNP
cord-347298-7kqrl3rv	692	11	et	et	NNP
cord-347298-7kqrl3rv	692	12	al	al	NNP
cord-347298-7kqrl3rv	692	13	.	.	.
cord-347298-7kqrl3rv	692	14	2006	2006	CD
cord-347298-7kqrl3rv	692	15	)	)	-RRB-
cord-347298-7kqrl3rv	692	16	,	,	,
cord-347298-7kqrl3rv	692	17	suggesting	suggest	VBG
cord-347298-7kqrl3rv	692	18	a	a	DT
cord-347298-7kqrl3rv	692	19	prominent	prominent	JJ
cord-347298-7kqrl3rv	692	20	role	role	NN
cord-347298-7kqrl3rv	692	21	in	in	IN
cord-347298-7kqrl3rv	692	22	creating	create	VBG
cord-347298-7kqrl3rv	692	23	testicular	testicular	JJ
cord-347298-7kqrl3rv	692	24	immune	immune	JJ
cord-347298-7kqrl3rv	692	25	privilege	privilege	NN
cord-347298-7kqrl3rv	692	26	.	.	.
cord-347298-7kqrl3rv	693	1	Accordingly	accordingly	RB
cord-347298-7kqrl3rv	693	2	,	,	,
cord-347298-7kqrl3rv	693	3	TGF	TGF	NNP
cord-347298-7kqrl3rv	693	4	1	1	CD
cord-347298-7kqrl3rv	693	5	contributes	contribute	VBZ
cord-347298-7kqrl3rv	693	6	to	to	IN
cord-347298-7kqrl3rv	693	7	the	the	DT
cord-347298-7kqrl3rv	693	8	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	693	9	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	693	10	activity	activity	NN
cord-347298-7kqrl3rv	693	11	of	of	IN
cord-347298-7kqrl3rv	693	12	testis	testis	NN
cord-347298-7kqrl3rv	693	13	extracts	extract	NNS
cord-347298-7kqrl3rv	693	14	(	(	-LRB-
cord-347298-7kqrl3rv	693	15	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	693	16	et	et	NNP
cord-347298-7kqrl3rv	693	17	al	al	NNP
cord-347298-7kqrl3rv	693	18	.	.	.
cord-347298-7kqrl3rv	693	19	1993	1993	CD
cord-347298-7kqrl3rv	693	20	)	)	-RRB-
cord-347298-7kqrl3rv	693	21	and	and	CC
cord-347298-7kqrl3rv	693	22	to	to	IN
cord-347298-7kqrl3rv	693	23	the	the	DT
cord-347298-7kqrl3rv	693	24	immunoprotective	immunoprotective	JJ
cord-347298-7kqrl3rv	693	25	properties	property	NNS
cord-347298-7kqrl3rv	693	26	of	of	IN
cord-347298-7kqrl3rv	693	27	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	693	28	cells	cell	NNS
cord-347298-7kqrl3rv	693	29	in	in	IN
cord-347298-7kqrl3rv	693	30	cotransplantation	cotransplantation	NN
cord-347298-7kqrl3rv	693	31	studies	study	NNS
cord-347298-7kqrl3rv	694	1	(	(	-LRB-
cord-347298-7kqrl3rv	694	2	Suarez	Suarez	NNP
cord-347298-7kqrl3rv	694	3	-	-	HYPH
cord-347298-7kqrl3rv	694	4	Pinzon	Pinzon	NNP
cord-347298-7kqrl3rv	694	5	et	et	NNP
cord-347298-7kqrl3rv	694	6	al	al	NNP
cord-347298-7kqrl3rv	694	7	.	.	.
cord-347298-7kqrl3rv	694	8	2000	2000	CD
cord-347298-7kqrl3rv	694	9	)	)	-RRB-
cord-347298-7kqrl3rv	694	10	.	.	.
cord-347298-7kqrl3rv	695	1	Activins	Activins	NNP
cord-347298-7kqrl3rv	695	2	are	be	VBP
cord-347298-7kqrl3rv	695	3	homodimers	homodimer	NNS
cord-347298-7kqrl3rv	695	4	or	or	CC
cord-347298-7kqrl3rv	695	5	heterodimers	heterodimer	NNS
cord-347298-7kqrl3rv	695	6	of	of	IN
cord-347298-7kqrl3rv	695	7	homologous	homologous	JJ
cord-347298-7kqrl3rv	695	8	subunits	subunit	NNS
cord-347298-7kqrl3rv	695	9	,	,	,
cord-347298-7kqrl3rv	695	10	designated	designate	VBD
cord-347298-7kqrl3rv	695	11	A	a	DT
cord-347298-7kqrl3rv	695	12	-E	-e	NN
cord-347298-7kqrl3rv	695	13	,	,	,
cord-347298-7kqrl3rv	695	14	which	which	WDT
cord-347298-7kqrl3rv	695	15	are	be	VBP
cord-347298-7kqrl3rv	695	16	structurally	structurally	RB
cord-347298-7kqrl3rv	695	17	related	related	JJ
cord-347298-7kqrl3rv	695	18	to	to	IN
cord-347298-7kqrl3rv	695	19	the	the	DT
cord-347298-7kqrl3rv	695	20	TGFs	tgf	NNS
cord-347298-7kqrl3rv	695	21	(	(	-LRB-
cord-347298-7kqrl3rv	695	22	Chang	Chang	NNP
cord-347298-7kqrl3rv	695	23	et	et	NNP
cord-347298-7kqrl3rv	695	24	al	al	NNP
cord-347298-7kqrl3rv	695	25	.	.	NNP
cord-347298-7kqrl3rv	695	26	2001	2001	CD
cord-347298-7kqrl3rv	695	27	;	;	:
cord-347298-7kqrl3rv	695	28	de	de	NNP
cord-347298-7kqrl3rv	695	29	Kretser	Kretser	NNP
cord-347298-7kqrl3rv	695	30	et	et	NNP
cord-347298-7kqrl3rv	695	31	al	al	NNP
cord-347298-7kqrl3rv	695	32	.	.	.
cord-347298-7kqrl3rv	695	33	2002	2002	CD
cord-347298-7kqrl3rv	695	34	)	)	-RRB-
cord-347298-7kqrl3rv	695	35	.	.	.
cord-347298-7kqrl3rv	696	1	Homodimers	Homodimers	NNP
cord-347298-7kqrl3rv	696	2	of	of	IN
cord-347298-7kqrl3rv	696	3	A	a	DT
cord-347298-7kqrl3rv	696	4	form	form	NN
cord-347298-7kqrl3rv	696	5	activin	activin	XX
cord-347298-7kqrl3rv	696	6	A	A	NNP
cord-347298-7kqrl3rv	696	7	,	,	,
cord-347298-7kqrl3rv	696	8	which	which	WDT
cord-347298-7kqrl3rv	696	9	is	be	VBZ
cord-347298-7kqrl3rv	696	10	widely	widely	RB
cord-347298-7kqrl3rv	696	11	expressed	express	VBN
cord-347298-7kqrl3rv	696	12	and	and	CC
cord-347298-7kqrl3rv	696	13	has	have	VBZ
cord-347298-7kqrl3rv	696	14	been	be	VBN
cord-347298-7kqrl3rv	696	15	extensively	extensively	RB
cord-347298-7kqrl3rv	696	16	studied	study	VBN
cord-347298-7kqrl3rv	696	17	.	.	.
cord-347298-7kqrl3rv	697	1	Relatively	relatively	RB
cord-347298-7kqrl3rv	697	2	less	less	JJR
cord-347298-7kqrl3rv	697	3	is	be	VBZ
cord-347298-7kqrl3rv	697	4	known	know	VBN
cord-347298-7kqrl3rv	697	5	about	about	IN
cord-347298-7kqrl3rv	697	6	the	the	DT
cord-347298-7kqrl3rv	697	7	other	other	JJ
cord-347298-7kqrl3rv	697	8	activin	activin	NNP
cord-347298-7kqrl3rv	697	9	forms	form	NNS
cord-347298-7kqrl3rv	697	10	,	,	,
cord-347298-7kqrl3rv	697	11	which	which	WDT
cord-347298-7kqrl3rv	697	12	appear	appear	VBP
cord-347298-7kqrl3rv	697	13	to	to	TO
cord-347298-7kqrl3rv	697	14	be	be	VB
cord-347298-7kqrl3rv	697	15	both	both	DT
cord-347298-7kqrl3rv	697	16	less	less	RBR
cord-347298-7kqrl3rv	697	17	abundant	abundant	JJ
cord-347298-7kqrl3rv	697	18	and	and	CC
cord-347298-7kqrl3rv	697	19	less	less	RBR
cord-347298-7kqrl3rv	697	20	widely	widely	RB
cord-347298-7kqrl3rv	697	21	distributed	distribute	VBN
cord-347298-7kqrl3rv	697	22	.	.	.
cord-347298-7kqrl3rv	698	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	698	2	A	A	NNP
cord-347298-7kqrl3rv	698	3	is	be	VBZ
cord-347298-7kqrl3rv	698	4	a	a	DT
cord-347298-7kqrl3rv	698	5	multifunctional	multifunctional	JJ
cord-347298-7kqrl3rv	698	6	growth	growth	NN
cord-347298-7kqrl3rv	698	7	factor	factor	NN
cord-347298-7kqrl3rv	698	8	and	and	CC
cord-347298-7kqrl3rv	698	9	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	698	10	regulator	regulator	NN
cord-347298-7kqrl3rv	699	1	(	(	-LRB-
cord-347298-7kqrl3rv	699	2	Phillips	Phillips	NNP
cord-347298-7kqrl3rv	699	3	et	et	NNP
cord-347298-7kqrl3rv	699	4	al	al	NNP
cord-347298-7kqrl3rv	699	5	.	.	NNP
cord-347298-7kqrl3rv	699	6	2001	2001	CD
cord-347298-7kqrl3rv	699	7	)	)	-RRB-
cord-347298-7kqrl3rv	699	8	,	,	,
cord-347298-7kqrl3rv	699	9	although	although	IN
cord-347298-7kqrl3rv	699	10	activins	activins	NNP
cord-347298-7kqrl3rv	699	11	were	be	VBD
cord-347298-7kqrl3rv	699	12	originally	originally	RB
cord-347298-7kqrl3rv	699	13	named	name	VBN
cord-347298-7kqrl3rv	699	14	for	for	IN
cord-347298-7kqrl3rv	699	15	the	the	DT
cord-347298-7kqrl3rv	699	16	ability	ability	NN
cord-347298-7kqrl3rv	699	17	of	of	IN
cord-347298-7kqrl3rv	699	18	activin	activin	NNP
cord-347298-7kqrl3rv	699	19	A	A	NNP
cord-347298-7kqrl3rv	699	20	and	and	CC
cord-347298-7kqrl3rv	699	21	B	B	NNP
cord-347298-7kqrl3rv	699	22	,	,	,
cord-347298-7kqrl3rv	699	23	in	in	IN
cord-347298-7kqrl3rv	699	24	particular	particular	JJ
cord-347298-7kqrl3rv	699	25	,	,	,
cord-347298-7kqrl3rv	699	26	to	to	TO
cord-347298-7kqrl3rv	699	27	stimulate	stimulate	VB
cord-347298-7kqrl3rv	699	28	pituitary	pituitary	JJ
cord-347298-7kqrl3rv	699	29	FSH	fsh	NN
cord-347298-7kqrl3rv	699	30	secretion	secretion	NN
cord-347298-7kqrl3rv	699	31	(	(	-LRB-
cord-347298-7kqrl3rv	699	32	Corrigan	Corrigan	NNP
cord-347298-7kqrl3rv	699	33	et	et	NNP
cord-347298-7kqrl3rv	699	34	al	al	NNP
cord-347298-7kqrl3rv	699	35	.	.	.
cord-347298-7kqrl3rv	699	36	1991	1991	CD
cord-347298-7kqrl3rv	699	37	;	;	:
cord-347298-7kqrl3rv	699	38	Ling	Ling	NNP
cord-347298-7kqrl3rv	699	39	et	et	FW
cord-347298-7kqrl3rv	699	40	al	al	NNP
cord-347298-7kqrl3rv	699	41	.	.	NNP
cord-347298-7kqrl3rv	699	42	1986	1986	CD
cord-347298-7kqrl3rv	699	43	)	)	-RRB-
cord-347298-7kqrl3rv	699	44	.	.	.
cord-347298-7kqrl3rv	700	1	Heterodimers	heterodimer	NNS
cord-347298-7kqrl3rv	700	2	of	of	IN
cord-347298-7kqrl3rv	700	3	either	either	DT
cord-347298-7kqrl3rv	700	4	A	a	NN
cord-347298-7kqrl3rv	700	5	or	or	CC
cord-347298-7kqrl3rv	700	6	B	b	NN
cord-347298-7kqrl3rv	700	7	subunits	subunit	NNS
cord-347298-7kqrl3rv	700	8	with	with	IN
cord-347298-7kqrl3rv	700	9	a	a	DT
cord-347298-7kqrl3rv	700	10	homologous	homologous	JJ
cord-347298-7kqrl3rv	700	11	subunit	subunit	NN
cord-347298-7kqrl3rv	700	12	,	,	,
cord-347298-7kqrl3rv	700	13	are	be	VBP
cord-347298-7kqrl3rv	700	14	called	call	VBN
cord-347298-7kqrl3rv	700	15	inhibin	inhibin	NNP
cord-347298-7kqrl3rv	701	1	A	a	NN
cord-347298-7kqrl3rv	701	2	and	and	CC
cord-347298-7kqrl3rv	701	3	inhibin	inhibin	NNP
cord-347298-7kqrl3rv	701	4	B	B	NNP
cord-347298-7kqrl3rv	701	5	,	,	,
cord-347298-7kqrl3rv	701	6	respectively	respectively	RB
cord-347298-7kqrl3rv	701	7	,	,	,
cord-347298-7kqrl3rv	701	8	and	and	CC
cord-347298-7kqrl3rv	701	9	act	act	VB
cord-347298-7kqrl3rv	701	10	as	as	IN
cord-347298-7kqrl3rv	701	11	feedback	feedback	NN
cord-347298-7kqrl3rv	701	12	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	701	13	of	of	IN
cord-347298-7kqrl3rv	701	14	FSH	fsh	NN
cord-347298-7kqrl3rv	701	15	secretion	secretion	NN
cord-347298-7kqrl3rv	701	16	from	from	IN
cord-347298-7kqrl3rv	701	17	the	the	DT
cord-347298-7kqrl3rv	701	18	pituitary	pituitary	NN
cord-347298-7kqrl3rv	701	19	(	(	-LRB-
cord-347298-7kqrl3rv	701	20	Robertson	Robertson	NNP
cord-347298-7kqrl3rv	701	21	et	et	NNP
cord-347298-7kqrl3rv	701	22	al	al	NNP
cord-347298-7kqrl3rv	701	23	.	.	NNP
cord-347298-7kqrl3rv	701	24	1986	1986	CD
cord-347298-7kqrl3rv	701	25	)	)	-RRB-
cord-347298-7kqrl3rv	701	26	.	.	.
cord-347298-7kqrl3rv	702	1	Unlike	unlike	IN
cord-347298-7kqrl3rv	702	2	the	the	DT
cord-347298-7kqrl3rv	702	3	activins	activin	NNS
cord-347298-7kqrl3rv	702	4	,	,	,
cord-347298-7kqrl3rv	702	5	inhibins	inhibin	NNS
cord-347298-7kqrl3rv	702	6	are	be	VBP
cord-347298-7kqrl3rv	702	7	not	not	RB
cord-347298-7kqrl3rv	702	8	widely	widely	RB
cord-347298-7kqrl3rv	702	9	produced	produce	VBN
cord-347298-7kqrl3rv	702	10	,	,	,
cord-347298-7kqrl3rv	702	11	and	and	CC
cord-347298-7kqrl3rv	702	12	their	-PRON-	PRP$
cord-347298-7kqrl3rv	702	13	chief	chief	JJ
cord-347298-7kqrl3rv	702	14	source	source	NN
cord-347298-7kqrl3rv	702	15	is	be	VBZ
cord-347298-7kqrl3rv	702	16	the	the	DT
cord-347298-7kqrl3rv	702	17	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	702	18	cell	cell	NN
cord-347298-7kqrl3rv	702	19	,	,	,
cord-347298-7kqrl3rv	702	20	the	the	DT
cord-347298-7kqrl3rv	702	21	cellular	cellular	JJ
cord-347298-7kqrl3rv	702	22	target	target	NN
cord-347298-7kqrl3rv	702	23	of	of	IN
cord-347298-7kqrl3rv	702	24	FSH	fsh	NN
cord-347298-7kqrl3rv	702	25	action	action	NN
cord-347298-7kqrl3rv	702	26	Meunier	Meunier	NNP
cord-347298-7kqrl3rv	702	27	et	et	FW
cord-347298-7kqrl3rv	702	28	al	al	NNP
cord-347298-7kqrl3rv	702	29	.	.	.
cord-347298-7kqrl3rv	702	30	1988	1988	CD
cord-347298-7kqrl3rv	702	31	)	)	-RRB-
cord-347298-7kqrl3rv	702	32	.	.	.
cord-347298-7kqrl3rv	703	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	703	2	functions	function	NNS
cord-347298-7kqrl3rv	703	3	are	be	VBP
cord-347298-7kqrl3rv	703	4	highly	highly	RB
cord-347298-7kqrl3rv	703	5	regulated	regulate	VBN
cord-347298-7kqrl3rv	703	6	.	.	.
cord-347298-7kqrl3rv	704	1	Like	like	IN
cord-347298-7kqrl3rv	704	2	the	the	DT
cord-347298-7kqrl3rv	704	3	TGFs	tgf	NNS
cord-347298-7kqrl3rv	704	4	,	,	,
cord-347298-7kqrl3rv	704	5	they	-PRON-	PRP
cord-347298-7kqrl3rv	704	6	act	act	VBP
cord-347298-7kqrl3rv	704	7	via	via	IN
cord-347298-7kqrl3rv	704	8	specific	specific	JJ
cord-347298-7kqrl3rv	704	9	type	type	NN
cord-347298-7kqrl3rv	704	10	I	-PRON-	PRP
cord-347298-7kqrl3rv	704	11	and	and	CC
cord-347298-7kqrl3rv	704	12	type	type	NN
cord-347298-7kqrl3rv	704	13	II	ii	CD
cord-347298-7kqrl3rv	704	14	transmembrane	transmembrane	NN
cord-347298-7kqrl3rv	704	15	serine	serine	NN
cord-347298-7kqrl3rv	704	16	/	/	SYM
cord-347298-7kqrl3rv	704	17	threonine	threonine	NN
cord-347298-7kqrl3rv	704	18	kinase	kinase	NN
cord-347298-7kqrl3rv	704	19	receptors	receptor	NNS
cord-347298-7kqrl3rv	704	20	,	,	,
cord-347298-7kqrl3rv	704	21	linked	link	VBN
cord-347298-7kqrl3rv	704	22	to	to	IN
cord-347298-7kqrl3rv	704	23	the	the	DT
cord-347298-7kqrl3rv	704	24	Smad	Smad	NNPS
cord-347298-7kqrl3rv	704	25	signaling	signal	VBG
cord-347298-7kqrl3rv	704	26	pathway	pathway	NN
cord-347298-7kqrl3rv	704	27	(	(	-LRB-
cord-347298-7kqrl3rv	704	28	Ethier	Ethier	NNP
cord-347298-7kqrl3rv	704	29	and	and	CC
cord-347298-7kqrl3rv	704	30	Findlay	Findlay	NNP
cord-347298-7kqrl3rv	704	31	2001	2001	CD
cord-347298-7kqrl3rv	704	32	;	;	:
cord-347298-7kqrl3rv	704	33	Vale	Vale	NNP
cord-347298-7kqrl3rv	704	34	et	et	FW
cord-347298-7kqrl3rv	704	35	al	al	NNP
cord-347298-7kqrl3rv	704	36	.	.	.
cord-347298-7kqrl3rv	704	37	2004	2004	CD
cord-347298-7kqrl3rv	704	38	)	)	-RRB-
cord-347298-7kqrl3rv	704	39	.	.	.
cord-347298-7kqrl3rv	705	1	The	the	DT
cord-347298-7kqrl3rv	705	2	inhibins	inhibin	NNS
cord-347298-7kqrl3rv	705	3	are	be	VBP
cord-347298-7kqrl3rv	705	4	competitive	competitive	JJ
cord-347298-7kqrl3rv	705	5	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	705	6	of	of	IN
cord-347298-7kqrl3rv	705	7	activin	activin	NNP
cord-347298-7kqrl3rv	705	8	receptor	receptor	NN
cord-347298-7kqrl3rv	705	9	binding	binding	NN
cord-347298-7kqrl3rv	705	10	,	,	,
cord-347298-7kqrl3rv	705	11	but	but	CC
cord-347298-7kqrl3rv	705	12	activin	activin	NNP
cord-347298-7kqrl3rv	705	13	homodimers	homodimer	NNS
cord-347298-7kqrl3rv	705	14	and	and	CC
cord-347298-7kqrl3rv	705	15	heterodimers	heterodimer	NNS
cord-347298-7kqrl3rv	705	16	comprising	comprise	VBG
cord-347298-7kqrl3rv	705	17	the	the	DT
cord-347298-7kqrl3rv	705	18	B	B	NNP
cord-347298-7kqrl3rv	705	19	and	and	CC
cord-347298-7kqrl3rv	705	20	C	C	NNP
cord-347298-7kqrl3rv	705	21	subunits	subunit	NNS
cord-347298-7kqrl3rv	705	22	also	also	RB
cord-347298-7kqrl3rv	705	23	appear	appear	VBP
cord-347298-7kqrl3rv	705	24	to	to	TO
cord-347298-7kqrl3rv	705	25	act	act	VB
cord-347298-7kqrl3rv	705	26	as	as	IN
cord-347298-7kqrl3rv	705	27	weak	weak	JJ
cord-347298-7kqrl3rv	705	28	competitive	competitive	JJ
cord-347298-7kqrl3rv	705	29	agonists	agonist	NNS
cord-347298-7kqrl3rv	705	30	of	of	IN
cord-347298-7kqrl3rv	705	31	activin	activin	NNP
cord-347298-7kqrl3rv	705	32	A	A	NNP
cord-347298-7kqrl3rv	705	33	(	(	-LRB-
cord-347298-7kqrl3rv	705	34	Brown	Brown	NNP
cord-347298-7kqrl3rv	705	35	et	et	NNP
cord-347298-7kqrl3rv	705	36	al	al	NNP
cord-347298-7kqrl3rv	705	37	.	.	.
cord-347298-7kqrl3rv	705	38	2000	2000	CD
cord-347298-7kqrl3rv	705	39	;	;	:
cord-347298-7kqrl3rv	705	40	Makanji	Makanji	NNP
cord-347298-7kqrl3rv	705	41	et	et	NNP
cord-347298-7kqrl3rv	705	42	al	al	NNP
cord-347298-7kqrl3rv	705	43	.	.	NNP
cord-347298-7kqrl3rv	705	44	2008	2008	CD
cord-347298-7kqrl3rv	705	45	;	;	:
cord-347298-7kqrl3rv	705	46	Mellor	Mellor	NNP
cord-347298-7kqrl3rv	705	47	et	et	NNP
cord-347298-7kqrl3rv	705	48	al	al	NNP
cord-347298-7kqrl3rv	705	49	.	.	NNP
cord-347298-7kqrl3rv	705	50	2003	2003	CD
cord-347298-7kqrl3rv	705	51	)	)	-RRB-
cord-347298-7kqrl3rv	705	52	.	.	.
cord-347298-7kqrl3rv	706	1	These	these	DT
cord-347298-7kqrl3rv	706	2	interactions	interaction	NNS
cord-347298-7kqrl3rv	706	3	are	be	VBP
cord-347298-7kqrl3rv	706	4	modulated	modulate	VBN
cord-347298-7kqrl3rv	706	5	and/or	and/or	CC
cord-347298-7kqrl3rv	706	6	facilitated	facilitate	VBN
cord-347298-7kqrl3rv	706	7	by	by	IN
cord-347298-7kqrl3rv	706	8	specific	specific	JJ
cord-347298-7kqrl3rv	706	9	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	706	10	coreceptor	coreceptor	NN
cord-347298-7kqrl3rv	706	11	proteins	protein	NNS
cord-347298-7kqrl3rv	706	12	,	,	,
cord-347298-7kqrl3rv	706	13	such	such	JJ
cord-347298-7kqrl3rv	706	14	as	as	IN
cord-347298-7kqrl3rv	706	15	betaglycan	betaglycan	NNP
cord-347298-7kqrl3rv	706	16	and	and	CC
cord-347298-7kqrl3rv	706	17	the	the	DT
cord-347298-7kqrl3rv	706	18	BMP	BMP	NNP
cord-347298-7kqrl3rv	706	19	and	and	CC
cord-347298-7kqrl3rv	706	20	activin	activin	NNP
cord-347298-7kqrl3rv	706	21	membrane	membrane	NN
cord-347298-7kqrl3rv	706	22	-	-	HYPH
cord-347298-7kqrl3rv	706	23	bound	bind	VBN
cord-347298-7kqrl3rv	706	24	inhibitor	inhibitor	NN
cord-347298-7kqrl3rv	706	25	(	(	-LRB-
cord-347298-7kqrl3rv	706	26	BAMBI	BAMBI	NNP
cord-347298-7kqrl3rv	706	27	)	)	-RRB-
cord-347298-7kqrl3rv	707	1	(	(	-LRB-
cord-347298-7kqrl3rv	707	2	Lewis	Lewis	NNP
cord-347298-7kqrl3rv	707	3	et	et	NNP
cord-347298-7kqrl3rv	707	4	al	al	NNP
cord-347298-7kqrl3rv	707	5	.	.	.
cord-347298-7kqrl3rv	708	1	2000	2000	CD
cord-347298-7kqrl3rv	708	2	;	;	:
cord-347298-7kqrl3rv	708	3	Makanji	Makanji	NNP
cord-347298-7kqrl3rv	708	4	et	et	NNP
cord-347298-7kqrl3rv	708	5	al	al	NNP
cord-347298-7kqrl3rv	708	6	.	.	.
cord-347298-7kqrl3rv	709	1	2008	2008	CD
cord-347298-7kqrl3rv	709	2	;	;	:
cord-347298-7kqrl3rv	709	3	Onichtchouk	Onichtchouk	NNP
cord-347298-7kqrl3rv	709	4	et	et	NNP
cord-347298-7kqrl3rv	709	5	al	al	NNP
cord-347298-7kqrl3rv	709	6	.	.	.
cord-347298-7kqrl3rv	709	7	1999	1999	CD
cord-347298-7kqrl3rv	709	8	)	)	-RRB-
cord-347298-7kqrl3rv	709	9	.	.	.
cord-347298-7kqrl3rv	710	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	710	2	,	,	,
cord-347298-7kqrl3rv	710	3	activin	activin	NNP
cord-347298-7kqrl3rv	710	4	bioactivity	bioactivity	NN
cord-347298-7kqrl3rv	710	5	can	can	MD
cord-347298-7kqrl3rv	710	6	be	be	VB
cord-347298-7kqrl3rv	710	7	effectively	effectively	RB
cord-347298-7kqrl3rv	710	8	neutralized	neutralize	VBN
cord-347298-7kqrl3rv	710	9	in	in	IN
cord-347298-7kqrl3rv	710	10	the	the	DT
cord-347298-7kqrl3rv	710	11	circulation	circulation	NN
cord-347298-7kqrl3rv	710	12	by	by	IN
cord-347298-7kqrl3rv	710	13	the	the	DT
cord-347298-7kqrl3rv	710	14	high	high	JJ
cord-347298-7kqrl3rv	710	15	-	-	HYPH
cord-347298-7kqrl3rv	710	16	affinity	affinity	NN
cord-347298-7kqrl3rv	710	17	activin	activin	NNP
cord-347298-7kqrl3rv	710	18	binding	bind	VBG
cord-347298-7kqrl3rv	710	19	protein	protein	NN
cord-347298-7kqrl3rv	710	20	,	,	,
cord-347298-7kqrl3rv	710	21	follistatin	follistatin	NNP
cord-347298-7kqrl3rv	710	22	(	(	-LRB-
cord-347298-7kqrl3rv	710	23	Nakamura	Nakamura	NNP
cord-347298-7kqrl3rv	710	24	et	et	NNP
cord-347298-7kqrl3rv	710	25	al	al	NNP
cord-347298-7kqrl3rv	710	26	.	.	NNP
cord-347298-7kqrl3rv	710	27	1991	1991	CD
cord-347298-7kqrl3rv	710	28	)	)	-RRB-
cord-347298-7kqrl3rv	710	29	.	.	.
cord-347298-7kqrl3rv	711	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	711	2	A	A	NNP
cord-347298-7kqrl3rv	711	3	is	be	VBZ
cord-347298-7kqrl3rv	711	4	abundantly	abundantly	RB
cord-347298-7kqrl3rv	711	5	produced	produce	VBN
cord-347298-7kqrl3rv	711	6	in	in	IN
cord-347298-7kqrl3rv	711	7	the	the	DT
cord-347298-7kqrl3rv	711	8	testis	testis	NN
cord-347298-7kqrl3rv	711	9	,	,	,
cord-347298-7kqrl3rv	711	10	particularly	particularly	RB
cord-347298-7kqrl3rv	711	11	during	during	IN
cord-347298-7kqrl3rv	711	12	early	early	JJ
cord-347298-7kqrl3rv	711	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	711	14	development	development	NN
cord-347298-7kqrl3rv	711	15	(	(	-LRB-
cord-347298-7kqrl3rv	711	16	Barakat	Barakat	NNP
cord-347298-7kqrl3rv	711	17	et	et	FW
cord-347298-7kqrl3rv	711	18	al	al	NNP
cord-347298-7kqrl3rv	711	19	.	.	NNP
cord-347298-7kqrl3rv	711	20	2008	2008	CD
cord-347298-7kqrl3rv	711	21	;	;	:
cord-347298-7kqrl3rv	711	22	Buzzard	Buzzard	NNP
cord-347298-7kqrl3rv	711	23	et	et	NNP
cord-347298-7kqrl3rv	711	24	al	al	NNP
cord-347298-7kqrl3rv	711	25	.	.	.
cord-347298-7kqrl3rv	711	26	2004	2004	CD
cord-347298-7kqrl3rv	711	27	)	)	-RRB-
cord-347298-7kqrl3rv	711	28	.	.	.
cord-347298-7kqrl3rv	712	1	Even	even	RB
cord-347298-7kqrl3rv	712	2	in	in	IN
cord-347298-7kqrl3rv	712	3	the	the	DT
cord-347298-7kqrl3rv	712	4	adult	adult	NN
cord-347298-7kqrl3rv	712	5	rat	rat	NN
cord-347298-7kqrl3rv	712	6	,	,	,
cord-347298-7kqrl3rv	712	7	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	712	8	fluid	fluid	JJ
cord-347298-7kqrl3rv	712	9	levels	level	NNS
cord-347298-7kqrl3rv	712	10	of	of	IN
cord-347298-7kqrl3rv	712	11	activin	activin	NNP
cord-347298-7kqrl3rv	712	12	A	A	NNP
cord-347298-7kqrl3rv	712	13	are	be	VBP
cord-347298-7kqrl3rv	712	14	5	5	CD
cord-347298-7kqrl3rv	712	15	-	-	SYM
cord-347298-7kqrl3rv	712	16	10	10	CD
cord-347298-7kqrl3rv	712	17	times	time	NNS
cord-347298-7kqrl3rv	712	18	higher	high	JJR
cord-347298-7kqrl3rv	712	19	than	than	IN
cord-347298-7kqrl3rv	712	20	normal	normal	JJ
cord-347298-7kqrl3rv	712	21	circulating	circulate	VBG
cord-347298-7kqrl3rv	712	22	concentrations	concentration	NNS
cord-347298-7kqrl3rv	712	23	(	(	-LRB-
cord-347298-7kqrl3rv	712	24	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	712	25	et	et	NNP
cord-347298-7kqrl3rv	712	26	al	al	NNP
cord-347298-7kqrl3rv	712	27	.	.	NNP
cord-347298-7kqrl3rv	712	28	2005	2005	CD
cord-347298-7kqrl3rv	712	29	)	)	-RRB-
cord-347298-7kqrl3rv	712	30	.	.	.
cord-347298-7kqrl3rv	713	1	The	the	DT
cord-347298-7kqrl3rv	713	2	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	713	3	cells	cell	NNS
cord-347298-7kqrl3rv	713	4	appear	appear	VBP
cord-347298-7kqrl3rv	713	5	to	to	TO
cord-347298-7kqrl3rv	713	6	be	be	VB
cord-347298-7kqrl3rv	713	7	the	the	DT
cord-347298-7kqrl3rv	713	8	main	main	JJ
cord-347298-7kqrl3rv	713	9	source	source	NN
cord-347298-7kqrl3rv	713	10	in	in	IN
cord-347298-7kqrl3rv	713	11	the	the	DT
cord-347298-7kqrl3rv	713	12	adult	adult	NN
cord-347298-7kqrl3rv	713	13	testis	testis	NN
cord-347298-7kqrl3rv	713	14	,	,	,
cord-347298-7kqrl3rv	713	15	although	although	IN
cord-347298-7kqrl3rv	713	16	the	the	DT
cord-347298-7kqrl3rv	713	17	A	A	NNP
cord-347298-7kqrl3rv	713	18	subunit	subunit	NN
cord-347298-7kqrl3rv	713	19	is	be	VBZ
cord-347298-7kqrl3rv	713	20	expressed	express	VBN
cord-347298-7kqrl3rv	713	21	in	in	IN
cord-347298-7kqrl3rv	713	22	most	most	JJS
cord-347298-7kqrl3rv	713	23	germ	germ	NN
cord-347298-7kqrl3rv	713	24	cells	cell	NNS
cord-347298-7kqrl3rv	713	25	Kaipia	Kaipia	NNP
cord-347298-7kqrl3rv	713	26	et	et	NNP
cord-347298-7kqrl3rv	713	27	al	al	NNP
cord-347298-7kqrl3rv	713	28	.	.	NNP
cord-347298-7kqrl3rv	713	29	1992	1992	CD
cord-347298-7kqrl3rv	713	30	)	)	-RRB-
cord-347298-7kqrl3rv	713	31	,	,	,
cord-347298-7kqrl3rv	713	32	and	and	CC
cord-347298-7kqrl3rv	713	33	activin	activin	NNP
cord-347298-7kqrl3rv	714	1	A	a	DT
cord-347298-7kqrl3rv	714	2	protein	protein	NN
cord-347298-7kqrl3rv	714	3	is	be	VBZ
cord-347298-7kqrl3rv	714	4	present	present	JJ
cord-347298-7kqrl3rv	714	5	in	in	IN
cord-347298-7kqrl3rv	714	6	the	the	DT
cord-347298-7kqrl3rv	714	7	resident	resident	JJ
cord-347298-7kqrl3rv	714	8	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	714	9	and	and	CC
cord-347298-7kqrl3rv	714	10	mast	mast	NN
cord-347298-7kqrl3rv	714	11	cells	cell	NNS
cord-347298-7kqrl3rv	715	1	(	(	-LRB-
cord-347298-7kqrl3rv	715	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	715	3	et	et	NNP
cord-347298-7kqrl3rv	715	4	al	al	NNP
cord-347298-7kqrl3rv	715	5	.	.	.
cord-347298-7kqrl3rv	716	1	2005b	2005b	CD
cord-347298-7kqrl3rv	717	1	(	(	-LRB-
cord-347298-7kqrl3rv	717	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	717	3	et	et	NNP
cord-347298-7kqrl3rv	717	4	al	al	NNP
cord-347298-7kqrl3rv	717	5	.	.	NNP
cord-347298-7kqrl3rv	717	6	,	,	,
cord-347298-7kqrl3rv	717	7	2006	2006	CD
cord-347298-7kqrl3rv	717	8	.	.	.
cord-347298-7kqrl3rv	718	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	718	2	A	A	NNP
cord-347298-7kqrl3rv	718	3	is	be	VBZ
cord-347298-7kqrl3rv	718	4	expressed	express	VBN
cord-347298-7kqrl3rv	718	5	at	at	IN
cord-347298-7kqrl3rv	718	6	low	low	JJ
cord-347298-7kqrl3rv	718	7	levels	level	NNS
cord-347298-7kqrl3rv	718	8	throughout	throughout	IN
cord-347298-7kqrl3rv	718	9	the	the	DT
cord-347298-7kqrl3rv	718	10	cycle	cycle	NN
cord-347298-7kqrl3rv	718	11	of	of	IN
cord-347298-7kqrl3rv	718	12	the	the	DT
cord-347298-7kqrl3rv	718	13	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	718	14	epithelium	epithelium	NN
cord-347298-7kqrl3rv	718	15	,	,	,
cord-347298-7kqrl3rv	718	16	but	but	CC
cord-347298-7kqrl3rv	718	17	there	there	EX
cord-347298-7kqrl3rv	718	18	is	be	VBZ
cord-347298-7kqrl3rv	718	19	a	a	DT
cord-347298-7kqrl3rv	718	20	distinct	distinct	JJ
cord-347298-7kqrl3rv	718	21	peak	peak	NN
cord-347298-7kqrl3rv	718	22	of	of	IN
cord-347298-7kqrl3rv	718	23	production	production	NN
cord-347298-7kqrl3rv	718	24	immediately	immediately	RB
cord-347298-7kqrl3rv	718	25	following	follow	VBG
cord-347298-7kqrl3rv	718	26	spermiation	spermiation	NN
cord-347298-7kqrl3rv	718	27	,	,	,
cord-347298-7kqrl3rv	718	28	which	which	WDT
cord-347298-7kqrl3rv	718	29	is	be	VBZ
cord-347298-7kqrl3rv	718	30	driven	drive	VBN
cord-347298-7kqrl3rv	718	31	by	by	IN
cord-347298-7kqrl3rv	718	32	the	the	DT
cord-347298-7kqrl3rv	718	33	surge	surge	NN
cord-347298-7kqrl3rv	718	34	of	of	IN
cord-347298-7kqrl3rv	718	35	IL	IL	NNP
cord-347298-7kqrl3rv	718	36	produced	produce	VBN
cord-347298-7kqrl3rv	718	37	by	by	IN
cord-347298-7kqrl3rv	718	38	the	the	DT
cord-347298-7kqrl3rv	718	39	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	718	40	cell	cell	NN
cord-347298-7kqrl3rv	718	41	at	at	IN
cord-347298-7kqrl3rv	718	42	this	this	DT
cord-347298-7kqrl3rv	718	43	time	time	NN
cord-347298-7kqrl3rv	718	44	(	(	-LRB-
cord-347298-7kqrl3rv	718	45	Kaipia	Kaipia	NNP
cord-347298-7kqrl3rv	718	46	et	et	NNP
cord-347298-7kqrl3rv	718	47	al	al	NNP
cord-347298-7kqrl3rv	718	48	.	.	.
cord-347298-7kqrl3rv	718	49	1992	1992	CD
cord-347298-7kqrl3rv	718	50	;	;	.
cord-347298-7kqrl3rv	719	1	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	719	2	et	et	NNP
cord-347298-7kqrl3rv	719	3	al	al	NNP
cord-347298-7kqrl3rv	719	4	.	.	.
cord-347298-7kqrl3rv	719	5	2006	2006	CD
cord-347298-7kqrl3rv	719	6	)	)	-RRB-
cord-347298-7kqrl3rv	719	7	.	.	.
cord-347298-7kqrl3rv	720	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	720	2	receptors	receptor	NNS
cord-347298-7kqrl3rv	720	3	are	be	VBP
cord-347298-7kqrl3rv	720	4	expressed	express	VBN
cord-347298-7kqrl3rv	720	5	by	by	IN
cord-347298-7kqrl3rv	720	6	most	most	JJS
cord-347298-7kqrl3rv	720	7	,	,	,
cord-347298-7kqrl3rv	720	8	if	if	IN
cord-347298-7kqrl3rv	720	9	not	not	RB
cord-347298-7kqrl3rv	720	10	all	all	DT
cord-347298-7kqrl3rv	720	11	,	,	,
cord-347298-7kqrl3rv	720	12	of	of	IN
cord-347298-7kqrl3rv	720	13	the	the	DT
cord-347298-7kqrl3rv	720	14	somatic	somatic	JJ
cord-347298-7kqrl3rv	720	15	and	and	CC
cord-347298-7kqrl3rv	720	16	germ	germ	NN
cord-347298-7kqrl3rv	720	17	cells	cell	NNS
cord-347298-7kqrl3rv	720	18	in	in	IN
cord-347298-7kqrl3rv	720	19	the	the	DT
cord-347298-7kqrl3rv	720	20	testis	testis	NN
cord-347298-7kqrl3rv	720	21	(	(	-LRB-
cord-347298-7kqrl3rv	720	22	Cameron	Cameron	NNP
cord-347298-7kqrl3rv	720	23	et	et	NNP
cord-347298-7kqrl3rv	720	24	al	al	NNP
cord-347298-7kqrl3rv	720	25	.	.	.
cord-347298-7kqrl3rv	720	26	1994	1994	CD
cord-347298-7kqrl3rv	720	27	;	;	:
cord-347298-7kqrl3rv	720	28	de	de	NNP
cord-347298-7kqrl3rv	720	29	Winter	Winter	NNP
cord-347298-7kqrl3rv	720	30	et	et	NNP
cord-347298-7kqrl3rv	720	31	al	al	NNP
cord-347298-7kqrl3rv	720	32	.	.	.
cord-347298-7kqrl3rv	720	33	1992	1992	CD
cord-347298-7kqrl3rv	720	34	;	;	:
cord-347298-7kqrl3rv	720	35	Feng	Feng	NNP
cord-347298-7kqrl3rv	720	36	et	et	FW
cord-347298-7kqrl3rv	720	37	al	al	NNP
cord-347298-7kqrl3rv	720	38	.	.	.
cord-347298-7kqrl3rv	720	39	1993	1993	CD
cord-347298-7kqrl3rv	721	1	;	;	:
cord-347298-7kqrl3rv	721	2	Kaipia	Kaipia	NNP
cord-347298-7kqrl3rv	721	3	et	et	NNP
cord-347298-7kqrl3rv	721	4	al	al	NNP
cord-347298-7kqrl3rv	721	5	.	.	.
cord-347298-7kqrl3rv	721	6	1993	1993	CD
cord-347298-7kqrl3rv	721	7	)	)	-RRB-
cord-347298-7kqrl3rv	721	8	.	.	.
cord-347298-7kqrl3rv	722	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	722	2	A	A	NNP
cord-347298-7kqrl3rv	722	3	exerts	exert	VBZ
cord-347298-7kqrl3rv	722	4	a	a	DT
cord-347298-7kqrl3rv	722	5	complex	complex	JJ
cord-347298-7kqrl3rv	722	6	regulation	regulation	NN
cord-347298-7kqrl3rv	722	7	of	of	IN
cord-347298-7kqrl3rv	722	8	germ	germ	NN
cord-347298-7kqrl3rv	722	9	cell	cell	NN
cord-347298-7kqrl3rv	722	10	,	,	,
cord-347298-7kqrl3rv	722	11	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	722	12	cell	cell	NN
cord-347298-7kqrl3rv	722	13	,	,	,
cord-347298-7kqrl3rv	722	14	and	and	CC
cord-347298-7kqrl3rv	722	15	Leydig	leydig	NN
cord-347298-7kqrl3rv	722	16	cell	cell	NN
cord-347298-7kqrl3rv	722	17	proliferation	proliferation	NN
cord-347298-7kqrl3rv	722	18	and/or	and/or	CC
cord-347298-7kqrl3rv	722	19	differentiation	differentiation	NN
cord-347298-7kqrl3rv	722	20	during	during	IN
cord-347298-7kqrl3rv	722	21	development	development	NN
cord-347298-7kqrl3rv	722	22	and	and	CC
cord-347298-7kqrl3rv	722	23	in	in	IN
cord-347298-7kqrl3rv	722	24	the	the	DT
cord-347298-7kqrl3rv	722	25	adult	adult	NN
cord-347298-7kqrl3rv	722	26	(	(	-LRB-
cord-347298-7kqrl3rv	722	27	Barakat	Barakat	NNP
cord-347298-7kqrl3rv	722	28	et	et	FW
cord-347298-7kqrl3rv	722	29	al	al	NNP
cord-347298-7kqrl3rv	722	30	.	.	NNP
cord-347298-7kqrl3rv	722	31	2008	2008	CD
cord-347298-7kqrl3rv	722	32	;	;	.
cord-347298-7kqrl3rv	723	1	Buzzard	Buzzard	NNP
cord-347298-7kqrl3rv	723	2	et	et	NNP
cord-347298-7kqrl3rv	723	3	al	al	NNP
cord-347298-7kqrl3rv	723	4	.	.	.
cord-347298-7kqrl3rv	724	1	2003	2003	CD
cord-347298-7kqrl3rv	724	2	;	;	:
cord-347298-7kqrl3rv	724	3	Mather	Mather	NNP
cord-347298-7kqrl3rv	724	4	et	et	NNP
cord-347298-7kqrl3rv	724	5	al	al	NNP
cord-347298-7kqrl3rv	724	6	.	.	NNP
cord-347298-7kqrl3rv	724	7	1990	1990	CD
cord-347298-7kqrl3rv	724	8	;	;	:
cord-347298-7kqrl3rv	724	9	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	724	10	et	et	NNP
cord-347298-7kqrl3rv	724	11	al	al	NNP
cord-347298-7kqrl3rv	724	12	.	.	.
cord-347298-7kqrl3rv	725	1	1991a	1991a	CD
cord-347298-7kqrl3rv	725	2	;	;	:
cord-347298-7kqrl3rv	725	3	Meehan	Meehan	NNP
cord-347298-7kqrl3rv	725	4	et	et	NNP
cord-347298-7kqrl3rv	725	5	al	al	NNP
cord-347298-7kqrl3rv	725	6	.	.	.
cord-347298-7kqrl3rv	726	1	2000	2000	CD
cord-347298-7kqrl3rv	726	2	;	;	:
cord-347298-7kqrl3rv	726	3	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	726	4	et	et	NNP
cord-347298-7kqrl3rv	726	5	al	al	NNP
cord-347298-7kqrl3rv	726	6	.	.	.
cord-347298-7kqrl3rv	726	7	2000	2000	CD
cord-347298-7kqrl3rv	726	8	)	)	-RRB-
cord-347298-7kqrl3rv	726	9	,	,	,
cord-347298-7kqrl3rv	726	10	and	and	CC
cord-347298-7kqrl3rv	726	11	disorders	disorder	NNS
cord-347298-7kqrl3rv	726	12	of	of	IN
cord-347298-7kqrl3rv	726	13	activin	activin	NNP
cord-347298-7kqrl3rv	726	14	signaling	signaling	NN
cord-347298-7kqrl3rv	726	15	are	be	VBP
cord-347298-7kqrl3rv	726	16	implicated	implicate	VBN
cord-347298-7kqrl3rv	726	17	in	in	IN
cord-347298-7kqrl3rv	726	18	the	the	DT
cord-347298-7kqrl3rv	726	19	onset	onset	NN
cord-347298-7kqrl3rv	726	20	of	of	IN
cord-347298-7kqrl3rv	726	21	testicular	testicular	JJ
cord-347298-7kqrl3rv	726	22	cancer	cancer	NN
cord-347298-7kqrl3rv	726	23	(	(	-LRB-
cord-347298-7kqrl3rv	726	24	Dias	Dias	NNP
cord-347298-7kqrl3rv	726	25	et	et	NNP
cord-347298-7kqrl3rv	726	26	al	al	NNP
cord-347298-7kqrl3rv	726	27	.	.	NNP
cord-347298-7kqrl3rv	726	28	2008	2008	CD
cord-347298-7kqrl3rv	726	29	)	)	-RRB-
cord-347298-7kqrl3rv	726	30	.	.	.
cord-347298-7kqrl3rv	727	1	Activin	Activin	NNP
cord-347298-7kqrl3rv	727	2	A	A	NNP
cord-347298-7kqrl3rv	727	3	is	be	VBZ
cord-347298-7kqrl3rv	727	4	produced	produce	VBN
cord-347298-7kqrl3rv	727	5	by	by	IN
cord-347298-7kqrl3rv	727	6	activated	activate	VBN
cord-347298-7kqrl3rv	727	7	monocytes	monocyte	NNS
cord-347298-7kqrl3rv	727	8	,	,	,
cord-347298-7kqrl3rv	727	9	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	727	10	,	,	,
cord-347298-7kqrl3rv	727	11	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	727	12	cells	cell	NNS
cord-347298-7kqrl3rv	727	13	,	,	,
cord-347298-7kqrl3rv	727	14	bone	bone	NN
cord-347298-7kqrl3rv	727	15	marrow	marrow	NN
cord-347298-7kqrl3rv	727	16	stromal	stromal	NN
cord-347298-7kqrl3rv	727	17	cells	cell	NNS
cord-347298-7kqrl3rv	727	18	,	,	,
cord-347298-7kqrl3rv	727	19	and	and	CC
cord-347298-7kqrl3rv	727	20	some	some	DT
cord-347298-7kqrl3rv	727	21	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	727	22	(	(	-LRB-
cord-347298-7kqrl3rv	727	23	Erämaa	Erämaa	NNP
cord-347298-7kqrl3rv	727	24	et	et	FW
cord-347298-7kqrl3rv	727	25	al	al	NNP
cord-347298-7kqrl3rv	727	26	.	.	.
cord-347298-7kqrl3rv	727	27	1992	1992	CD
cord-347298-7kqrl3rv	727	28	;	;	:
cord-347298-7kqrl3rv	727	29	Ogawa	Ogawa	NNP
cord-347298-7kqrl3rv	727	30	et	et	NNP
cord-347298-7kqrl3rv	727	31	al	al	NNP
cord-347298-7kqrl3rv	727	32	.	.	.
cord-347298-7kqrl3rv	728	1	2006	2006	CD
cord-347298-7kqrl3rv	729	1	;	;	:
cord-347298-7kqrl3rv	729	2	Robson	Robson	NNP
cord-347298-7kqrl3rv	729	3	et	et	NNP
cord-347298-7kqrl3rv	729	4	al	al	NNP
cord-347298-7kqrl3rv	729	5	.	.	.
cord-347298-7kqrl3rv	729	6	2008	2008	CD
cord-347298-7kqrl3rv	730	1	;	;	:
cord-347298-7kqrl3rv	730	2	Yamashita	Yamashita	NNP
cord-347298-7kqrl3rv	730	3	et	et	NNP
cord-347298-7kqrl3rv	730	4	al	al	NNP
cord-347298-7kqrl3rv	730	5	.	.	NNP
cord-347298-7kqrl3rv	730	6	1992	1992	CD
cord-347298-7kqrl3rv	730	7	)	)	-RRB-
cord-347298-7kqrl3rv	730	8	,	,	,
cord-347298-7kqrl3rv	730	9	and	and	CC
cord-347298-7kqrl3rv	730	10	plays	play	VBZ
cord-347298-7kqrl3rv	730	11	a	a	DT
cord-347298-7kqrl3rv	730	12	facilitating	facilitate	VBG
cord-347298-7kqrl3rv	730	13	role	role	NN
cord-347298-7kqrl3rv	730	14	in	in	IN
cord-347298-7kqrl3rv	730	15	early	early	JJ
cord-347298-7kqrl3rv	730	16	inflammation	inflammation	NN
cord-347298-7kqrl3rv	730	17	responses	response	NNS
cord-347298-7kqrl3rv	730	18	(	(	-LRB-
cord-347298-7kqrl3rv	730	19	Jones	Jones	NNP
cord-347298-7kqrl3rv	730	20	et	et	NNP
cord-347298-7kqrl3rv	730	21	al	al	NNP
cord-347298-7kqrl3rv	730	22	.	.	NNP
cord-347298-7kqrl3rv	730	23	2007	2007	CD
cord-347298-7kqrl3rv	730	24	)	)	-RRB-
cord-347298-7kqrl3rv	730	25	.	.	.
cord-347298-7kqrl3rv	731	1	Consistent	consistent	JJ
cord-347298-7kqrl3rv	731	2	with	with	IN
cord-347298-7kqrl3rv	731	3	its	-PRON-	PRP$
cord-347298-7kqrl3rv	731	4	homology	homology	NN
cord-347298-7kqrl3rv	731	5	to	to	IN
cord-347298-7kqrl3rv	731	6	the	the	DT
cord-347298-7kqrl3rv	731	7	TGF	TGF	NNP
cord-347298-7kqrl3rv	731	8	proteins	protein	NNS
cord-347298-7kqrl3rv	731	9	,	,	,
cord-347298-7kqrl3rv	731	10	however	however	RB
cord-347298-7kqrl3rv	731	11	,	,	,
cord-347298-7kqrl3rv	731	12	activin	activin	NNP
cord-347298-7kqrl3rv	731	13	A	A	NNP
cord-347298-7kqrl3rv	731	14	also	also	RB
cord-347298-7kqrl3rv	731	15	possesses	possess	VBZ
cord-347298-7kqrl3rv	731	16	a	a	DT
cord-347298-7kqrl3rv	731	17	repertoire	repertoire	NN
cord-347298-7kqrl3rv	731	18	of	of	IN
cord-347298-7kqrl3rv	731	19	anti	anti	JJ
cord-347298-7kqrl3rv	731	20	-	-	JJ
cord-347298-7kqrl3rv	731	21	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	731	22	and	and	CC
cord-347298-7kqrl3rv	731	23	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	731	24	activities	activity	NNS
cord-347298-7kqrl3rv	731	25	,	,	,
cord-347298-7kqrl3rv	731	26	and	and	CC
cord-347298-7kqrl3rv	731	27	displays	display	VBZ
cord-347298-7kqrl3rv	731	28	characteristics	characteristic	NNS
cord-347298-7kqrl3rv	731	29	of	of	IN
cord-347298-7kqrl3rv	731	30	a	a	DT
cord-347298-7kqrl3rv	731	31	type	type	NN
cord-347298-7kqrl3rv	731	32	2	2	CD
cord-347298-7kqrl3rv	731	33	cytokine	cytokine	NN
cord-347298-7kqrl3rv	731	34	(	(	-LRB-
cord-347298-7kqrl3rv	731	35	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	731	36	et	et	NNP
cord-347298-7kqrl3rv	731	37	al	al	NNP
cord-347298-7kqrl3rv	731	38	.	.	NNP
cord-347298-7kqrl3rv	731	39	1989	1989	CD
cord-347298-7kqrl3rv	731	40	;	;	:
cord-347298-7kqrl3rv	731	41	Ogawa	Ogawa	NNP
cord-347298-7kqrl3rv	731	42	et	et	NNP
cord-347298-7kqrl3rv	731	43	al	al	NNP
cord-347298-7kqrl3rv	731	44	.	.	.
cord-347298-7kqrl3rv	731	45	2006	2006	CD
cord-347298-7kqrl3rv	731	46	;	;	:
cord-347298-7kqrl3rv	731	47	Wang	Wang	NNP
cord-347298-7kqrl3rv	731	48	et	et	NNP
cord-347298-7kqrl3rv	731	49	al	al	NNP
cord-347298-7kqrl3rv	731	50	.	.	.
cord-347298-7kqrl3rv	732	1	2008	2008	CD
cord-347298-7kqrl3rv	732	2	;	;	:
cord-347298-7kqrl3rv	732	3	Yu	Yu	NNP
cord-347298-7kqrl3rv	732	4	et	et	NNP
cord-347298-7kqrl3rv	732	5	al	al	NNP
cord-347298-7kqrl3rv	732	6	.	.	NNP
cord-347298-7kqrl3rv	732	7	1998	1998	CD
cord-347298-7kqrl3rv	732	8	)	)	-RRB-
cord-347298-7kqrl3rv	732	9	.	.	.
cord-347298-7kqrl3rv	733	1	In	in	IN
cord-347298-7kqrl3rv	733	2	various	various	JJ
cord-347298-7kqrl3rv	733	3	experimental	experimental	JJ
cord-347298-7kqrl3rv	733	4	systems	system	NNS
cord-347298-7kqrl3rv	733	5	,	,	,
cord-347298-7kqrl3rv	733	6	activin	activin	NNP
cord-347298-7kqrl3rv	733	7	A	A	NNP
cord-347298-7kqrl3rv	733	8	has	have	VBZ
cord-347298-7kqrl3rv	733	9	been	be	VBN
cord-347298-7kqrl3rv	733	10	found	find	VBN
cord-347298-7kqrl3rv	733	11	to	to	TO
cord-347298-7kqrl3rv	733	12	antagonize	antagonize	VB
cord-347298-7kqrl3rv	733	13	the	the	DT
cord-347298-7kqrl3rv	733	14	production	production	NN
cord-347298-7kqrl3rv	733	15	and	and	CC
cord-347298-7kqrl3rv	733	16	actions	action	NNS
cord-347298-7kqrl3rv	733	17	of	of	IN
cord-347298-7kqrl3rv	733	18	IL1	IL1	NNP
cord-347298-7kqrl3rv	733	19	and	and	CC
cord-347298-7kqrl3rv	733	20	IL6	IL6	NNP
cord-347298-7kqrl3rv	733	21	,	,	,
cord-347298-7kqrl3rv	733	22	to	to	TO
cord-347298-7kqrl3rv	733	23	inhibit	inhibit	VB
cord-347298-7kqrl3rv	733	24	critical	critical	JJ
cord-347298-7kqrl3rv	733	25	T	t	NN
cord-347298-7kqrl3rv	733	26	cell	cell	NN
cord-347298-7kqrl3rv	733	27	and	and	CC
cord-347298-7kqrl3rv	733	28	B	b	NN
cord-347298-7kqrl3rv	733	29	cell	cell	NN
cord-347298-7kqrl3rv	733	30	activation	activation	NN
cord-347298-7kqrl3rv	733	31	responses	response	NNS
cord-347298-7kqrl3rv	733	32	,	,	,
cord-347298-7kqrl3rv	733	33	and	and	CC
cord-347298-7kqrl3rv	733	34	to	to	TO
cord-347298-7kqrl3rv	733	35	induce	induce	VB
cord-347298-7kqrl3rv	733	36	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	733	37	to	to	TO
cord-347298-7kqrl3rv	733	38	polarize	polarize	VB
cord-347298-7kqrl3rv	733	39	toward	toward	IN
cord-347298-7kqrl3rv	733	40	the	the	DT
cord-347298-7kqrl3rv	733	41	M2	m2	JJ
cord-347298-7kqrl3rv	733	42	phenotype	phenotype	NN
cord-347298-7kqrl3rv	733	43	(	(	-LRB-
cord-347298-7kqrl3rv	733	44	Brosh	Brosh	NNP
cord-347298-7kqrl3rv	733	45	et	et	NNP
cord-347298-7kqrl3rv	733	46	al	al	NNP
cord-347298-7kqrl3rv	733	47	.	.	NNP
cord-347298-7kqrl3rv	733	48	1995	1995	CD
cord-347298-7kqrl3rv	733	49	;	;	:
cord-347298-7kqrl3rv	733	50	Gribi	Gribi	NNP
cord-347298-7kqrl3rv	733	51	et	et	NNP
cord-347298-7kqrl3rv	733	52	al	al	NNP
cord-347298-7kqrl3rv	733	53	.	.	.
cord-347298-7kqrl3rv	734	1	2001	2001	CD
cord-347298-7kqrl3rv	734	2	;	;	:
cord-347298-7kqrl3rv	734	3	Ogawa	Ogawa	NNP
cord-347298-7kqrl3rv	734	4	et	et	NNP
cord-347298-7kqrl3rv	734	5	al	al	NNP
cord-347298-7kqrl3rv	734	6	.	.	.
cord-347298-7kqrl3rv	735	1	2006	2006	CD
cord-347298-7kqrl3rv	736	1	;	;	:
cord-347298-7kqrl3rv	736	2	Russell	Russell	NNP
cord-347298-7kqrl3rv	736	3	et	et	NNP
cord-347298-7kqrl3rv	736	4	al	al	NNP
cord-347298-7kqrl3rv	736	5	.	.	.
cord-347298-7kqrl3rv	736	6	1999	1999	CD
cord-347298-7kqrl3rv	736	7	)	)	-RRB-
cord-347298-7kqrl3rv	736	8	.	.	.
cord-347298-7kqrl3rv	737	1	Both	both	DT
cord-347298-7kqrl3rv	737	2	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	737	3	cells	cell	NNS
cord-347298-7kqrl3rv	737	4	and	and	CC
cord-347298-7kqrl3rv	737	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	737	6	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	737	7	in	in	IN
cord-347298-7kqrl3rv	737	8	culture	culture	NN
cord-347298-7kqrl3rv	737	9	respond	respond	VBP
cord-347298-7kqrl3rv	737	10	to	to	IN
cord-347298-7kqrl3rv	737	11	LPS	LPS	NNP
cord-347298-7kqrl3rv	737	12	by	by	IN
cord-347298-7kqrl3rv	737	13	increasing	increase	VBG
cord-347298-7kqrl3rv	737	14	activin	activin	NNP
cord-347298-7kqrl3rv	737	15	A	a	DT
cord-347298-7kqrl3rv	737	16	production	production	NN
cord-347298-7kqrl3rv	738	1	(	(	-LRB-
cord-347298-7kqrl3rv	738	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	738	3	et	et	NNP
cord-347298-7kqrl3rv	738	4	al	al	NNP
cord-347298-7kqrl3rv	738	5	.	.	NNP
cord-347298-7kqrl3rv	738	6	2005a	2005a	CD
cord-347298-7kqrl3rv	738	7	)	)	-RRB-
cord-347298-7kqrl3rv	739	1	(	(	-LRB-
cord-347298-7kqrl3rv	739	2	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	739	3	,	,	,
cord-347298-7kqrl3rv	739	4	unpublished	unpublished	JJ
cord-347298-7kqrl3rv	739	5	data	datum	NNS
cord-347298-7kqrl3rv	739	6	)	)	-RRB-
cord-347298-7kqrl3rv	739	7	,	,	,
cord-347298-7kqrl3rv	739	8	and	and	CC
cord-347298-7kqrl3rv	739	9	IL1	IL1	NNP
cord-347298-7kqrl3rv	739	10	is	be	VBZ
cord-347298-7kqrl3rv	739	11	a	a	DT
cord-347298-7kqrl3rv	739	12	very	very	RB
cord-347298-7kqrl3rv	739	13	potent	potent	JJ
cord-347298-7kqrl3rv	739	14	stimulus	stimulus	NN
cord-347298-7kqrl3rv	739	15	for	for	IN
cord-347298-7kqrl3rv	739	16	activin	activin	NNP
cord-347298-7kqrl3rv	740	1	A	a	DT
cord-347298-7kqrl3rv	740	2	production	production	NN
cord-347298-7kqrl3rv	740	3	by	by	IN
cord-347298-7kqrl3rv	740	4	the	the	DT
cord-347298-7kqrl3rv	740	5	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	740	6	cell	cell	NN
cord-347298-7kqrl3rv	741	1	(	(	-LRB-
cord-347298-7kqrl3rv	741	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	741	3	et	et	NNP
cord-347298-7kqrl3rv	741	4	al	al	NNP
cord-347298-7kqrl3rv	741	5	.	.	.
cord-347298-7kqrl3rv	742	1	2005b	2005b	CD
cord-347298-7kqrl3rv	743	1	(	(	-LRB-
cord-347298-7kqrl3rv	743	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	743	3	et	et	NNP
cord-347298-7kqrl3rv	743	4	al	al	NNP
cord-347298-7kqrl3rv	743	5	.	.	NNP
cord-347298-7kqrl3rv	743	6	,	,	,
cord-347298-7kqrl3rv	743	7	2006	2006	CD
cord-347298-7kqrl3rv	743	8	.	.	.
cord-347298-7kqrl3rv	744	1	The	the	DT
cord-347298-7kqrl3rv	744	2	actual	actual	JJ
cord-347298-7kqrl3rv	744	3	role	role	NN
cord-347298-7kqrl3rv	744	4	of	of	IN
cord-347298-7kqrl3rv	744	5	activin	activin	NNP
cord-347298-7kqrl3rv	744	6	A	A	NNP
cord-347298-7kqrl3rv	744	7	in	in	IN
cord-347298-7kqrl3rv	744	8	testicular	testicular	JJ
cord-347298-7kqrl3rv	744	9	inflammation	inflammation	NN
cord-347298-7kqrl3rv	744	10	remains	remain	VBZ
cord-347298-7kqrl3rv	744	11	unclear	unclear	JJ
cord-347298-7kqrl3rv	744	12	,	,	,
cord-347298-7kqrl3rv	744	13	since	since	IN
cord-347298-7kqrl3rv	744	14	the	the	DT
cord-347298-7kqrl3rv	744	15	high	high	JJ
cord-347298-7kqrl3rv	744	16	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	744	17	levels	level	NNS
cord-347298-7kqrl3rv	744	18	of	of	IN
cord-347298-7kqrl3rv	744	19	activin	activin	NNP
cord-347298-7kqrl3rv	744	20	A	A	NNP
cord-347298-7kqrl3rv	744	21	are	be	VBP
cord-347298-7kqrl3rv	744	22	not	not	RB
cord-347298-7kqrl3rv	744	23	affected	affect	VBN
cord-347298-7kqrl3rv	744	24	by	by	IN
cord-347298-7kqrl3rv	744	25	LPS	LPS	NNP
cord-347298-7kqrl3rv	744	26	treatment	treatment	NN
cord-347298-7kqrl3rv	744	27	in	in	IN
cord-347298-7kqrl3rv	744	28	vivo	vivo	NN
cord-347298-7kqrl3rv	745	1	(	(	-LRB-
cord-347298-7kqrl3rv	745	2	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	745	3	et	et	NNP
cord-347298-7kqrl3rv	745	4	al	al	NNP
cord-347298-7kqrl3rv	745	5	.	.	NNP
cord-347298-7kqrl3rv	745	6	2005	2005	CD
cord-347298-7kqrl3rv	745	7	)	)	-RRB-
cord-347298-7kqrl3rv	745	8	,	,	,
cord-347298-7kqrl3rv	745	9	but	but	CC
cord-347298-7kqrl3rv	745	10	a	a	DT
cord-347298-7kqrl3rv	745	11	role	role	NN
cord-347298-7kqrl3rv	745	12	for	for	IN
cord-347298-7kqrl3rv	745	13	activin	activin	NNP
cord-347298-7kqrl3rv	745	14	A	A	NNP
cord-347298-7kqrl3rv	745	15	in	in	IN
cord-347298-7kqrl3rv	745	16	modulating	modulate	VBG
cord-347298-7kqrl3rv	745	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	745	18	immune	immune	JJ
cord-347298-7kqrl3rv	745	19	responses	response	NNS
cord-347298-7kqrl3rv	745	20	can	can	MD
cord-347298-7kqrl3rv	745	21	be	be	VB
cord-347298-7kqrl3rv	745	22	predicted	predict	VBN
cord-347298-7kqrl3rv	745	23	.	.	.
cord-347298-7kqrl3rv	746	1	Androgens	androgen	NNS
cord-347298-7kqrl3rv	746	2	produced	produce	VBN
cord-347298-7kqrl3rv	746	3	by	by	IN
cord-347298-7kqrl3rv	746	4	the	the	DT
cord-347298-7kqrl3rv	746	5	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	746	6	cells	cell	NNS
cord-347298-7kqrl3rv	746	7	have	have	VBP
cord-347298-7kqrl3rv	746	8	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	746	9	properties	property	NNS
cord-347298-7kqrl3rv	746	10	that	that	WDT
cord-347298-7kqrl3rv	746	11	contribute	contribute	VBP
cord-347298-7kqrl3rv	746	12	to	to	IN
cord-347298-7kqrl3rv	746	13	differences	difference	NNS
cord-347298-7kqrl3rv	746	14	in	in	IN
cord-347298-7kqrl3rv	746	15	immunity	immunity	NN
cord-347298-7kqrl3rv	746	16	between	between	IN
cord-347298-7kqrl3rv	746	17	the	the	DT
cord-347298-7kqrl3rv	746	18	sexes	sex	NNS
cord-347298-7kqrl3rv	746	19	(	(	-LRB-
cord-347298-7kqrl3rv	746	20	Cutolo	Cutolo	NNP
cord-347298-7kqrl3rv	746	21	et	et	NNP
cord-347298-7kqrl3rv	746	22	al	al	NNP
cord-347298-7kqrl3rv	746	23	.	.	.
cord-347298-7kqrl3rv	747	1	2004	2004	CD
cord-347298-7kqrl3rv	747	2	;	;	:
cord-347298-7kqrl3rv	747	3	Miller	Miller	NNP
cord-347298-7kqrl3rv	747	4	and	and	CC
cord-347298-7kqrl3rv	747	5	Hunt	Hunt	NNP
cord-347298-7kqrl3rv	747	6	1996	1996	CD
cord-347298-7kqrl3rv	747	7	)	)	-RRB-
cord-347298-7kqrl3rv	747	8	.	.	.
cord-347298-7kqrl3rv	748	1	The	the	DT
cord-347298-7kqrl3rv	748	2	majority	majority	NN
cord-347298-7kqrl3rv	748	3	of	of	IN
cord-347298-7kqrl3rv	748	4	these	these	DT
cord-347298-7kqrl3rv	748	5	effects	effect	NNS
cord-347298-7kqrl3rv	748	6	are	be	VBP
cord-347298-7kqrl3rv	748	7	believed	believe	VBN
cord-347298-7kqrl3rv	748	8	to	to	TO
cord-347298-7kqrl3rv	748	9	be	be	VB
cord-347298-7kqrl3rv	748	10	exerted	exert	VBN
cord-347298-7kqrl3rv	748	11	at	at	IN
cord-347298-7kqrl3rv	748	12	the	the	DT
cord-347298-7kqrl3rv	748	13	level	level	NN
cord-347298-7kqrl3rv	748	14	of	of	IN
cord-347298-7kqrl3rv	748	15	the	the	DT
cord-347298-7kqrl3rv	748	16	immune	immune	JJ
cord-347298-7kqrl3rv	748	17	tissues	tissue	NNS
cord-347298-7kqrl3rv	748	18	,	,	,
cord-347298-7kqrl3rv	748	19	rather	rather	RB
cord-347298-7kqrl3rv	748	20	than	than	IN
cord-347298-7kqrl3rv	748	21	by	by	IN
cord-347298-7kqrl3rv	748	22	direct	direct	JJ
cord-347298-7kqrl3rv	748	23	effects	effect	NNS
cord-347298-7kqrl3rv	748	24	on	on	IN
cord-347298-7kqrl3rv	748	25	circulating	circulate	VBG
cord-347298-7kqrl3rv	748	26	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	748	27	,	,	,
cord-347298-7kqrl3rv	748	28	which	which	WDT
cord-347298-7kqrl3rv	748	29	lack	lack	VBP
cord-347298-7kqrl3rv	748	30	classical	classical	JJ
cord-347298-7kqrl3rv	748	31	androgen	androgen	NN
cord-347298-7kqrl3rv	748	32	receptors	receptor	NNS
cord-347298-7kqrl3rv	748	33	(	(	-LRB-
cord-347298-7kqrl3rv	748	34	Grossman	Grossman	NNP
cord-347298-7kqrl3rv	748	35	et	et	NNP
cord-347298-7kqrl3rv	748	36	al	al	NNP
cord-347298-7kqrl3rv	748	37	.	.	.
cord-347298-7kqrl3rv	748	38	1979	1979	CD
cord-347298-7kqrl3rv	748	39	;	;	:
cord-347298-7kqrl3rv	748	40	Sasson	Sasson	NNP
cord-347298-7kqrl3rv	748	41	and	and	CC
cord-347298-7kqrl3rv	748	42	Mayer	Mayer	NNP
cord-347298-7kqrl3rv	748	43	1981	1981	CD
cord-347298-7kqrl3rv	748	44	)	)	-RRB-
cord-347298-7kqrl3rv	748	45	.	.	.
cord-347298-7kqrl3rv	749	1	Recently	recently	RB
cord-347298-7kqrl3rv	749	2	,	,	,
cord-347298-7kqrl3rv	749	3	however	however	RB
cord-347298-7kqrl3rv	749	4	,	,	,
cord-347298-7kqrl3rv	749	5	it	-PRON-	PRP
cord-347298-7kqrl3rv	749	6	has	have	VBZ
cord-347298-7kqrl3rv	749	7	been	be	VBN
cord-347298-7kqrl3rv	749	8	discovered	discover	VBN
cord-347298-7kqrl3rv	749	9	that	that	IN
cord-347298-7kqrl3rv	749	10	steroids	steroid	NNS
cord-347298-7kqrl3rv	749	11	can	can	MD
cord-347298-7kqrl3rv	749	12	interact	interact	VB
cord-347298-7kqrl3rv	749	13	with	with	IN
cord-347298-7kqrl3rv	749	14	membrane	membrane	NN
cord-347298-7kqrl3rv	749	15	-	-	HYPH
cord-347298-7kqrl3rv	749	16	bound	bind	VBN
cord-347298-7kqrl3rv	749	17	G	g	NN
cord-347298-7kqrl3rv	749	18	-	-	HYPH
cord-347298-7kqrl3rv	749	19	protein	protein	NN
cord-347298-7kqrl3rv	749	20	-	-	HYPH
cord-347298-7kqrl3rv	749	21	coupled	couple	VBN
cord-347298-7kqrl3rv	749	22	receptors	receptor	NNS
cord-347298-7kqrl3rv	749	23	to	to	TO
cord-347298-7kqrl3rv	749	24	trigger	trigger	VB
cord-347298-7kqrl3rv	749	25	nongenomic	nongenomic	JJ
cord-347298-7kqrl3rv	749	26	responses	response	NNS
cord-347298-7kqrl3rv	749	27	(	(	-LRB-
cord-347298-7kqrl3rv	749	28	Braun	Braun	NNP
cord-347298-7kqrl3rv	749	29	and	and	CC
cord-347298-7kqrl3rv	749	30	Thomas	Thomas	NNP
cord-347298-7kqrl3rv	749	31	2004	2004	CD
cord-347298-7kqrl3rv	749	32	;	;	:
cord-347298-7kqrl3rv	749	33	Rahman	Rahman	NNP
cord-347298-7kqrl3rv	749	34	and	and	CC
cord-347298-7kqrl3rv	749	35	Christian	Christian	NNP
cord-347298-7kqrl3rv	749	36	2007	2007	CD
cord-347298-7kqrl3rv	749	37	)	)	-RRB-
cord-347298-7kqrl3rv	749	38	.	.	.
cord-347298-7kqrl3rv	750	1	Studies	study	NNS
cord-347298-7kqrl3rv	750	2	have	have	VBP
cord-347298-7kqrl3rv	750	3	shown	show	VBN
cord-347298-7kqrl3rv	750	4	that	that	IN
cord-347298-7kqrl3rv	750	5	androgens	androgen	NNS
cord-347298-7kqrl3rv	750	6	alter	alter	VB
cord-347298-7kqrl3rv	750	7	[	[	-LRB-
cord-347298-7kqrl3rv	750	8	Ca	Ca	NNP
cord-347298-7kqrl3rv	750	9	]	]	-RRB-
cord-347298-7kqrl3rv	750	10	fluxes	flux	NNS
cord-347298-7kqrl3rv	750	11	in	in	IN
cord-347298-7kqrl3rv	750	12	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	750	13	and	and	CC
cord-347298-7kqrl3rv	750	14	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	750	15	via	via	IN
cord-347298-7kqrl3rv	750	16	such	such	JJ
cord-347298-7kqrl3rv	750	17	membrane	membrane	NN
cord-347298-7kqrl3rv	750	18	-	-	HYPH
cord-347298-7kqrl3rv	750	19	mediated	mediate	VBN
cord-347298-7kqrl3rv	750	20	interactions	interaction	NNS
cord-347298-7kqrl3rv	750	21	,	,	,
cord-347298-7kqrl3rv	750	22	affecting	affect	VBG
cord-347298-7kqrl3rv	750	23	gene	gene	NN
cord-347298-7kqrl3rv	750	24	expression	expression	NN
cord-347298-7kqrl3rv	750	25	and	and	CC
cord-347298-7kqrl3rv	750	26	function	function	NN
cord-347298-7kqrl3rv	750	27	in	in	IN
cord-347298-7kqrl3rv	750	28	the	the	DT
cord-347298-7kqrl3rv	750	29	target	target	NN
cord-347298-7kqrl3rv	750	30	cells	cell	NNS
cord-347298-7kqrl3rv	750	31	(	(	-LRB-
cord-347298-7kqrl3rv	750	32	Benten	Benten	NNP
cord-347298-7kqrl3rv	750	33	et	et	NNP
cord-347298-7kqrl3rv	750	34	al	al	NNP
cord-347298-7kqrl3rv	750	35	.	.	.
cord-347298-7kqrl3rv	751	1	2004	2004	CD
cord-347298-7kqrl3rv	751	2	;	;	:
cord-347298-7kqrl3rv	751	3	Walker	Walker	NNP
cord-347298-7kqrl3rv	751	4	2003	2003	CD
cord-347298-7kqrl3rv	751	5	;	;	:
cord-347298-7kqrl3rv	751	6	Wunderlich	Wunderlich	NNP
cord-347298-7kqrl3rv	751	7	et	et	NNP
cord-347298-7kqrl3rv	751	8	al	al	NNP
cord-347298-7kqrl3rv	751	9	.	.	.
cord-347298-7kqrl3rv	751	10	2002	2002	CD
cord-347298-7kqrl3rv	751	11	)	)	-RRB-
cord-347298-7kqrl3rv	751	12	.	.	.
cord-347298-7kqrl3rv	752	1	Although	although	IN
cord-347298-7kqrl3rv	752	2	studies	study	NNS
cord-347298-7kqrl3rv	752	3	of	of	IN
cord-347298-7kqrl3rv	752	4	the	the	DT
cord-347298-7kqrl3rv	752	5	role	role	NN
cord-347298-7kqrl3rv	752	6	of	of	IN
cord-347298-7kqrl3rv	752	7	androgens	androgen	NNS
cord-347298-7kqrl3rv	752	8	in	in	IN
cord-347298-7kqrl3rv	752	9	suppressing	suppress	VBG
cord-347298-7kqrl3rv	752	10	immune	immune	JJ
cord-347298-7kqrl3rv	752	11	responses	response	NNS
cord-347298-7kqrl3rv	752	12	,	,	,
cord-347298-7kqrl3rv	752	13	such	such	JJ
cord-347298-7kqrl3rv	752	14	as	as	IN
cord-347298-7kqrl3rv	752	15	graft	graft	NN
cord-347298-7kqrl3rv	752	16	rejection	rejection	NN
cord-347298-7kqrl3rv	752	17	,	,	,
cord-347298-7kqrl3rv	752	18	in	in	IN
cord-347298-7kqrl3rv	752	19	the	the	DT
cord-347298-7kqrl3rv	752	20	testis	testis	NN
cord-347298-7kqrl3rv	752	21	have	have	VBP
cord-347298-7kqrl3rv	752	22	been	be	VBN
cord-347298-7kqrl3rv	752	23	somewhat	somewhat	RB
cord-347298-7kqrl3rv	752	24	equivocal	equivocal	JJ
cord-347298-7kqrl3rv	752	25	(	(	-LRB-
cord-347298-7kqrl3rv	752	26	Cameron	Cameron	NNP
cord-347298-7kqrl3rv	752	27	et	et	NNP
cord-347298-7kqrl3rv	752	28	al	al	NNP
cord-347298-7kqrl3rv	752	29	.	.	NNP
cord-347298-7kqrl3rv	752	30	1990	1990	CD
cord-347298-7kqrl3rv	752	31	;	;	:
cord-347298-7kqrl3rv	752	32	Selawry	Selawry	NNP
cord-347298-7kqrl3rv	752	33	and	and	CC
cord-347298-7kqrl3rv	752	34	Whittington	Whittington	NNP
cord-347298-7kqrl3rv	752	35	1988	1988	CD
cord-347298-7kqrl3rv	752	36	;	;	:
cord-347298-7kqrl3rv	752	37	Whitmore	Whitmore	NNP
cord-347298-7kqrl3rv	752	38	and	and	CC
cord-347298-7kqrl3rv	752	39	Gittes	Gittes	NNP
cord-347298-7kqrl3rv	752	40	1978	1978	CD
cord-347298-7kqrl3rv	752	41	)	)	-RRB-
cord-347298-7kqrl3rv	752	42	,	,	,
cord-347298-7kqrl3rv	752	43	the	the	DT
cord-347298-7kqrl3rv	752	44	observation	observation	NN
cord-347298-7kqrl3rv	752	45	that	that	IN
cord-347298-7kqrl3rv	752	46	immune	immune	JJ
cord-347298-7kqrl3rv	752	47	cells	cell	NNS
cord-347298-7kqrl3rv	752	48	can	can	MD
cord-347298-7kqrl3rv	752	49	respond	respond	VB
cord-347298-7kqrl3rv	752	50	directly	directly	RB
cord-347298-7kqrl3rv	752	51	to	to	IN
cord-347298-7kqrl3rv	752	52	androgens	androgen	NNS
cord-347298-7kqrl3rv	752	53	has	have	VBZ
cord-347298-7kqrl3rv	752	54	resurrected	resurrect	VBN
cord-347298-7kqrl3rv	752	55	the	the	DT
cord-347298-7kqrl3rv	752	56	intriguing	intriguing	JJ
cord-347298-7kqrl3rv	752	57	possibility	possibility	NN
cord-347298-7kqrl3rv	752	58	that	that	IN
cord-347298-7kqrl3rv	752	59	androgens	androgen	NNS
cord-347298-7kqrl3rv	752	60	,	,	,
cord-347298-7kqrl3rv	752	61	and	and	CC
cord-347298-7kqrl3rv	752	62	possibly	possibly	RB
cord-347298-7kqrl3rv	752	63	other	other	JJ
cord-347298-7kqrl3rv	752	64	testicular	testicular	JJ
cord-347298-7kqrl3rv	752	65	steroids	steroid	NNS
cord-347298-7kqrl3rv	752	66	,	,	,
cord-347298-7kqrl3rv	752	67	may	may	MD
cord-347298-7kqrl3rv	752	68	directly	directly	RB
cord-347298-7kqrl3rv	752	69	regulate	regulate	VB
cord-347298-7kqrl3rv	752	70	immune	immune	JJ
cord-347298-7kqrl3rv	752	71	cell	cell	NN
cord-347298-7kqrl3rv	752	72	activity	activity	NN
cord-347298-7kqrl3rv	752	73	within	within	IN
cord-347298-7kqrl3rv	752	74	the	the	DT
cord-347298-7kqrl3rv	752	75	testis	testis	NN
cord-347298-7kqrl3rv	752	76	and	and	CC
cord-347298-7kqrl3rv	752	77	adjacent	adjacent	JJ
cord-347298-7kqrl3rv	752	78	draining	drain	VBG
cord-347298-7kqrl3rv	752	79	lymph	lymph	NN
cord-347298-7kqrl3rv	752	80	nodes	node	NNS
cord-347298-7kqrl3rv	752	81	.	.	.
cord-347298-7kqrl3rv	753	1	Glucocorticoids	Glucocorticoids	NNP
cord-347298-7kqrl3rv	753	2	play	play	VBP
cord-347298-7kqrl3rv	753	3	an	an	DT
cord-347298-7kqrl3rv	753	4	important	important	JJ
cord-347298-7kqrl3rv	753	5	role	role	NN
cord-347298-7kqrl3rv	753	6	in	in	IN
cord-347298-7kqrl3rv	753	7	modulating	modulate	VBG
cord-347298-7kqrl3rv	753	8	both	both	CC
cord-347298-7kqrl3rv	753	9	testicular	testicular	JJ
cord-347298-7kqrl3rv	753	10	immunity	immunity	NN
cord-347298-7kqrl3rv	753	11	and	and	CC
cord-347298-7kqrl3rv	753	12	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	753	13	via	via	IN
cord-347298-7kqrl3rv	753	14	a	a	DT
cord-347298-7kqrl3rv	753	15	complex	complex	JJ
cord-347298-7kqrl3rv	753	16	extratesticular	extratesticular	JJ
cord-347298-7kqrl3rv	753	17	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	753	18	loop	loop	NN
cord-347298-7kqrl3rv	753	19	.	.	.
cord-347298-7kqrl3rv	754	1	During	during	IN
cord-347298-7kqrl3rv	754	2	inflammation	inflammation	NN
cord-347298-7kqrl3rv	754	3	,	,	,
cord-347298-7kqrl3rv	754	4	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	754	5	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	754	6	activate	activate	VBP
cord-347298-7kqrl3rv	754	7	the	the	DT
cord-347298-7kqrl3rv	754	8	hypothalamic	hypothalamic	JJ
cord-347298-7kqrl3rv	754	9	-	-	HYPH
cord-347298-7kqrl3rv	754	10	pituitary	pituitary	NN
cord-347298-7kqrl3rv	754	11	-	-	HYPH
cord-347298-7kqrl3rv	754	12	adrenal	adrenal	NN
cord-347298-7kqrl3rv	754	13	axis	axis	NN
cord-347298-7kqrl3rv	754	14	leading	lead	VBG
cord-347298-7kqrl3rv	754	15	to	to	IN
cord-347298-7kqrl3rv	754	16	increased	increase	VBN
cord-347298-7kqrl3rv	754	17	secretion	secretion	NN
cord-347298-7kqrl3rv	754	18	of	of	IN
cord-347298-7kqrl3rv	754	19	glucocorticoids	glucocorticoid	NNS
cord-347298-7kqrl3rv	754	20	,	,	,
cord-347298-7kqrl3rv	754	21	which	which	WDT
cord-347298-7kqrl3rv	754	22	act	act	VBP
cord-347298-7kqrl3rv	754	23	through	through	IN
cord-347298-7kqrl3rv	754	24	the	the	DT
cord-347298-7kqrl3rv	754	25	ubiquitously	ubiquitously	RB
cord-347298-7kqrl3rv	754	26	expressed	express	VBN
cord-347298-7kqrl3rv	754	27	glucocorticoid	glucocorticoid	NN
cord-347298-7kqrl3rv	754	28	receptors	receptor	NNS
cord-347298-7kqrl3rv	754	29	(	(	-LRB-
cord-347298-7kqrl3rv	754	30	Buckingham	Buckingham	NNP
cord-347298-7kqrl3rv	754	31	et	et	NNP
cord-347298-7kqrl3rv	754	32	al	al	NNP
cord-347298-7kqrl3rv	754	33	.	.	.
cord-347298-7kqrl3rv	754	34	1996	1996	CD
cord-347298-7kqrl3rv	754	35	;	;	:
cord-347298-7kqrl3rv	754	36	Sapolsky	Sapolsky	NNP
cord-347298-7kqrl3rv	754	37	et	et	FW
cord-347298-7kqrl3rv	754	38	al	al	NNP
cord-347298-7kqrl3rv	754	39	.	.	.
cord-347298-7kqrl3rv	754	40	2000	2000	CD
cord-347298-7kqrl3rv	754	41	)	)	-RRB-
cord-347298-7kqrl3rv	754	42	.	.	.
cord-347298-7kqrl3rv	755	1	Glucocorticoids	Glucocorticoids	NNP
cord-347298-7kqrl3rv	755	2	suppress	suppress	VBP
cord-347298-7kqrl3rv	755	3	innate	innate	JJ
cord-347298-7kqrl3rv	755	4	and	and	CC
cord-347298-7kqrl3rv	755	5	acquired	acquire	VBN
cord-347298-7kqrl3rv	755	6	immunity	immunity	NN
cord-347298-7kqrl3rv	755	7	at	at	IN
cord-347298-7kqrl3rv	755	8	multiple	multiple	JJ
cord-347298-7kqrl3rv	755	9	levels	level	NNS
cord-347298-7kqrl3rv	755	10	and	and	CC
cord-347298-7kqrl3rv	755	11	are	be	VBP
cord-347298-7kqrl3rv	755	12	an	an	DT
cord-347298-7kqrl3rv	755	13	essential	essential	JJ
cord-347298-7kqrl3rv	755	14	control	control	NN
cord-347298-7kqrl3rv	755	15	in	in	IN
cord-347298-7kqrl3rv	755	16	the	the	DT
cord-347298-7kqrl3rv	755	17	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	755	18	/	/	SYM
cord-347298-7kqrl3rv	755	19	immune	immune	JJ
cord-347298-7kqrl3rv	755	20	response	response	NN
cord-347298-7kqrl3rv	755	21	.	.	.
cord-347298-7kqrl3rv	756	1	They	-PRON-	PRP
cord-347298-7kqrl3rv	756	2	inhibit	inhibit	VBP
cord-347298-7kqrl3rv	756	3	the	the	DT
cord-347298-7kqrl3rv	756	4	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	756	5	response	response	NN
cord-347298-7kqrl3rv	756	6	primarily	primarily	RB
cord-347298-7kqrl3rv	756	7	by	by	IN
cord-347298-7kqrl3rv	756	8	repression	repression	NN
cord-347298-7kqrl3rv	756	9	of	of	IN
cord-347298-7kqrl3rv	756	10	NFB	NFB	NNP
cord-347298-7kqrl3rv	756	11	,	,	,
cord-347298-7kqrl3rv	756	12	suppressing	suppress	VBG
cord-347298-7kqrl3rv	756	13	the	the	DT
cord-347298-7kqrl3rv	756	14	production	production	NN
cord-347298-7kqrl3rv	756	15	and	and	CC
cord-347298-7kqrl3rv	756	16	actions	action	NNS
cord-347298-7kqrl3rv	756	17	of	of	IN
cord-347298-7kqrl3rv	756	18	the	the	DT
cord-347298-7kqrl3rv	756	19	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	756	20	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	756	21	,	,	,
cord-347298-7kqrl3rv	756	22	reducing	reduce	VBG
cord-347298-7kqrl3rv	756	23	adhesion	adhesion	NN
cord-347298-7kqrl3rv	756	24	molecule	molecule	NN
cord-347298-7kqrl3rv	756	25	expression	expression	NN
cord-347298-7kqrl3rv	756	26	,	,	,
cord-347298-7kqrl3rv	756	27	and	and	CC
cord-347298-7kqrl3rv	756	28	stimulating	stimulate	VBG
cord-347298-7kqrl3rv	756	29	the	the	DT
cord-347298-7kqrl3rv	756	30	production	production	NN
cord-347298-7kqrl3rv	756	31	of	of	IN
cord-347298-7kqrl3rv	756	32	anti	anti	JJ
cord-347298-7kqrl3rv	756	33	-	-	JJ
cord-347298-7kqrl3rv	756	34	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	756	35	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	756	36	(	(	-LRB-
cord-347298-7kqrl3rv	756	37	Auphan	Auphan	NNP
cord-347298-7kqrl3rv	756	38	et	et	NNP
cord-347298-7kqrl3rv	756	39	al	al	NNP
cord-347298-7kqrl3rv	756	40	.	.	NNP
cord-347298-7kqrl3rv	756	41	1995	1995	CD
cord-347298-7kqrl3rv	756	42	;	;	:
cord-347298-7kqrl3rv	756	43	Brack	Brack	NNP
cord-347298-7kqrl3rv	756	44	et	et	NNP
cord-347298-7kqrl3rv	756	45	al	al	NNP
cord-347298-7kqrl3rv	756	46	.	.	.
cord-347298-7kqrl3rv	756	47	1997	1997	CD
cord-347298-7kqrl3rv	756	48	;	;	:
cord-347298-7kqrl3rv	756	49	Kapcala	Kapcala	NNP
cord-347298-7kqrl3rv	756	50	et	et	NNP
cord-347298-7kqrl3rv	756	51	al	al	NNP
cord-347298-7kqrl3rv	756	52	.	.	NNP
cord-347298-7kqrl3rv	756	53	1995	1995	CD
cord-347298-7kqrl3rv	756	54	)	)	-RRB-
cord-347298-7kqrl3rv	756	55	.	.	.
cord-347298-7kqrl3rv	757	1	Glucocorticoids	Glucocorticoids	NNP
cord-347298-7kqrl3rv	757	2	also	also	RB
cord-347298-7kqrl3rv	757	3	exert	exert	VBP
cord-347298-7kqrl3rv	757	4	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	757	5	effects	effect	NNS
cord-347298-7kqrl3rv	757	6	at	at	IN
cord-347298-7kqrl3rv	757	7	all	all	DT
cord-347298-7kqrl3rv	757	8	levels	level	NNS
cord-347298-7kqrl3rv	757	9	of	of	IN
cord-347298-7kqrl3rv	757	10	the	the	DT
cord-347298-7kqrl3rv	757	11	hypothalamic	hypothalamic	JJ
cord-347298-7kqrl3rv	757	12	-	-	HYPH
cord-347298-7kqrl3rv	757	13	pituitary	pituitary	NN
cord-347298-7kqrl3rv	757	14	-	-	HYPH
cord-347298-7kqrl3rv	757	15	Leydig	leydig	NN
cord-347298-7kqrl3rv	757	16	cell	cell	NN
cord-347298-7kqrl3rv	757	17	axis	axis	NN
cord-347298-7kqrl3rv	757	18	(	(	-LRB-
cord-347298-7kqrl3rv	757	19	Bambino	Bambino	NNP
cord-347298-7kqrl3rv	757	20	and	and	CC
cord-347298-7kqrl3rv	757	21	Hsueh	Hsueh	NNP
cord-347298-7kqrl3rv	757	22	1981	1981	CD
cord-347298-7kqrl3rv	757	23	;	;	:
cord-347298-7kqrl3rv	757	24	Hales	Hales	NNP
cord-347298-7kqrl3rv	757	25	and	and	CC
cord-347298-7kqrl3rv	757	26	Payne	Payne	NNP
cord-347298-7kqrl3rv	757	27	1989	1989	CD
cord-347298-7kqrl3rv	757	28	;	;	:
cord-347298-7kqrl3rv	757	29	Hardy	Hardy	NNP
cord-347298-7kqrl3rv	757	30	et	et	NNP
cord-347298-7kqrl3rv	757	31	al	al	NNP
cord-347298-7kqrl3rv	757	32	.	.	NNP
cord-347298-7kqrl3rv	757	33	2005	2005	CD
cord-347298-7kqrl3rv	757	34	;	;	:
cord-347298-7kqrl3rv	757	35	Monder	Monder	NNP
cord-347298-7kqrl3rv	757	36	et	et	NNP
cord-347298-7kqrl3rv	757	37	al	al	NNP
cord-347298-7kqrl3rv	757	38	.	.	.
cord-347298-7kqrl3rv	757	39	1994	1994	CD
cord-347298-7kqrl3rv	757	40	)	)	-RRB-
cord-347298-7kqrl3rv	757	41	,	,	,
cord-347298-7kqrl3rv	757	42	thereby	thereby	RB
cord-347298-7kqrl3rv	757	43	contributing	contribute	VBG
cord-347298-7kqrl3rv	757	44	to	to	IN
cord-347298-7kqrl3rv	757	45	the	the	DT
cord-347298-7kqrl3rv	757	46	inhibition	inhibition	NN
cord-347298-7kqrl3rv	757	47	of	of	IN
cord-347298-7kqrl3rv	757	48	androgen	androgen	NN
cord-347298-7kqrl3rv	757	49	production	production	NN
cord-347298-7kqrl3rv	757	50	that	that	WDT
cord-347298-7kqrl3rv	757	51	accompanies	accompany	VBZ
cord-347298-7kqrl3rv	757	52	local	local	JJ
cord-347298-7kqrl3rv	757	53	and	and	CC
cord-347298-7kqrl3rv	757	54	systemic	systemic	JJ
cord-347298-7kqrl3rv	757	55	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	757	56	events	event	NNS
cord-347298-7kqrl3rv	757	57	.	.	.
cord-347298-7kqrl3rv	758	1	Prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	758	2	(	(	-LRB-
cord-347298-7kqrl3rv	758	3	PGD	PGD	NNP
cord-347298-7kqrl3rv	758	4	,	,	,
cord-347298-7kqrl3rv	758	5	PGE	PGE	NNP
cord-347298-7kqrl3rv	758	6	,	,	,
cord-347298-7kqrl3rv	758	7	and	and	CC
cord-347298-7kqrl3rv	758	8	PGF	PGF	NNP
cord-347298-7kqrl3rv	758	9	)	)	-RRB-
cord-347298-7kqrl3rv	758	10	,	,	,
cord-347298-7kqrl3rv	758	11	prostacyclins	prostacyclins	NNP
cord-347298-7kqrl3rv	758	12	(	(	-LRB-
cord-347298-7kqrl3rv	758	13	PGI	PGI	NNP
cord-347298-7kqrl3rv	758	14	)	)	-RRB-
cord-347298-7kqrl3rv	758	15	,	,	,
cord-347298-7kqrl3rv	758	16	and	and	CC
cord-347298-7kqrl3rv	758	17	thromboxanes	thromboxanes	NNP
cord-347298-7kqrl3rv	758	18	(	(	-LRB-
cord-347298-7kqrl3rv	758	19	Tx	Tx	NNP
cord-347298-7kqrl3rv	758	20	)	)	-RRB-
cord-347298-7kqrl3rv	758	21	,	,	,
cord-347298-7kqrl3rv	758	22	collectively	collectively	RB
cord-347298-7kqrl3rv	758	23	called	call	VBN
cord-347298-7kqrl3rv	758	24	the	the	DT
cord-347298-7kqrl3rv	758	25	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	758	26	,	,	,
cord-347298-7kqrl3rv	758	27	are	be	VBP
cord-347298-7kqrl3rv	758	28	fundamental	fundamental	JJ
cord-347298-7kqrl3rv	758	29	to	to	IN
cord-347298-7kqrl3rv	758	30	many	many	JJ
cord-347298-7kqrl3rv	758	31	physiological	physiological	JJ
cord-347298-7kqrl3rv	758	32	processes	process	NNS
cord-347298-7kqrl3rv	758	33	,	,	,
cord-347298-7kqrl3rv	758	34	including	include	VBG
cord-347298-7kqrl3rv	758	35	inflammation	inflammation	NN
cord-347298-7kqrl3rv	758	36	and	and	CC
cord-347298-7kqrl3rv	758	37	immunity	immunity	NN
cord-347298-7kqrl3rv	758	38	.	.	.
cord-347298-7kqrl3rv	759	1	Prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	759	2	arise	arise	VBP
cord-347298-7kqrl3rv	759	3	from	from	IN
cord-347298-7kqrl3rv	759	4	hydrolysis	hydrolysis	NN
cord-347298-7kqrl3rv	759	5	of	of	IN
cord-347298-7kqrl3rv	759	6	membrane	membrane	NN
cord-347298-7kqrl3rv	759	7	glycerophospholipids	glycerophospholipid	NNS
cord-347298-7kqrl3rv	759	8	to	to	TO
cord-347298-7kqrl3rv	759	9	release	release	VB
cord-347298-7kqrl3rv	759	10	the	the	DT
cord-347298-7kqrl3rv	759	11	free	free	JJ
cord-347298-7kqrl3rv	759	12	fatty	fatty	JJ
cord-347298-7kqrl3rv	759	13	acid	acid	NN
cord-347298-7kqrl3rv	759	14	arachidonic	arachidonic	NN
cord-347298-7kqrl3rv	759	15	acid	acid	NN
cord-347298-7kqrl3rv	759	16	through	through	IN
cord-347298-7kqrl3rv	759	17	the	the	DT
cord-347298-7kqrl3rv	759	18	action	action	NN
cord-347298-7kqrl3rv	759	19	of	of	IN
cord-347298-7kqrl3rv	759	20	one	one	CD
cord-347298-7kqrl3rv	759	21	of	of	IN
cord-347298-7kqrl3rv	759	22	the	the	DT
cord-347298-7kqrl3rv	759	23	more	more	JJR
cord-347298-7kqrl3rv	759	24	than	than	IN
cord-347298-7kqrl3rv	759	25	20	20	CD
cord-347298-7kqrl3rv	759	26	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	759	27	with	with	IN
cord-347298-7kqrl3rv	759	28	phospholipase	phospholipase	NN
cord-347298-7kqrl3rv	759	29	A	a	DT
cord-347298-7kqrl3rv	759	30	2	2	CD
cord-347298-7kqrl3rv	760	1	(	(	-LRB-
cord-347298-7kqrl3rv	760	2	PLA	PLA	NNP
cord-347298-7kqrl3rv	760	3	2	2	CD
cord-347298-7kqrl3rv	760	4	)	)	-RRB-
cord-347298-7kqrl3rv	760	5	activity	activity	NN
cord-347298-7kqrl3rv	760	6	(	(	-LRB-
cord-347298-7kqrl3rv	760	7	Kudo	Kudo	NNP
cord-347298-7kqrl3rv	760	8	and	and	CC
cord-347298-7kqrl3rv	760	9	Murakami	Murakami	NNP
cord-347298-7kqrl3rv	760	10	2002	2002	CD
cord-347298-7kqrl3rv	760	11	;	;	:
cord-347298-7kqrl3rv	761	1	Schaloske	Schaloske	NNP
cord-347298-7kqrl3rv	761	2	and	and	CC
cord-347298-7kqrl3rv	761	3	Dennis	Dennis	NNP
cord-347298-7kqrl3rv	761	4	2006	2006	CD
cord-347298-7kqrl3rv	761	5	)	)	-RRB-
cord-347298-7kqrl3rv	761	6	.	.	.
cord-347298-7kqrl3rv	762	1	Arachidonic	arachidonic	JJ
cord-347298-7kqrl3rv	762	2	acid	acid	NN
cord-347298-7kqrl3rv	762	3	is	be	VBZ
cord-347298-7kqrl3rv	762	4	in	in	IN
cord-347298-7kqrl3rv	762	5	turn	turn	NN
cord-347298-7kqrl3rv	762	6	directed	direct	VBN
cord-347298-7kqrl3rv	762	7	down	down	IN
cord-347298-7kqrl3rv	762	8	the	the	DT
cord-347298-7kqrl3rv	762	9	prostanoid	prostanoid	JJ
cord-347298-7kqrl3rv	762	10	synthetic	synthetic	JJ
cord-347298-7kqrl3rv	762	11	pathway	pathway	NN
cord-347298-7kqrl3rv	762	12	by	by	IN
cord-347298-7kqrl3rv	762	13	the	the	DT
cord-347298-7kqrl3rv	762	14	action	action	NN
cord-347298-7kqrl3rv	762	15	of	of	IN
cord-347298-7kqrl3rv	762	16	the	the	DT
cord-347298-7kqrl3rv	762	17	cyclooxygenase	cyclooxygenase	NN
cord-347298-7kqrl3rv	762	18	(	(	-LRB-
cord-347298-7kqrl3rv	762	19	COX	COX	NNP
cord-347298-7kqrl3rv	762	20	;	;	:
cord-347298-7kqrl3rv	762	21	also	also	RB
cord-347298-7kqrl3rv	762	22	called	call	VBN
cord-347298-7kqrl3rv	762	23	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	762	24	-	-	HYPH
cord-347298-7kqrl3rv	762	25	endoperoxide	endoperoxide	NN
cord-347298-7kqrl3rv	762	26	synthase	synthase	NN
cord-347298-7kqrl3rv	762	27	)	)	-RRB-
cord-347298-7kqrl3rv	762	28	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	762	29	(	(	-LRB-
cord-347298-7kqrl3rv	762	30	Figure	figure	NN
cord-347298-7kqrl3rv	762	31	3	3	CD
cord-347298-7kqrl3rv	762	32	)	)	-RRB-
cord-347298-7kqrl3rv	762	33	.	.	.
cord-347298-7kqrl3rv	763	1	There	there	EX
cord-347298-7kqrl3rv	763	2	are	be	VBP
cord-347298-7kqrl3rv	763	3	two	two	CD
cord-347298-7kqrl3rv	763	4	COX	COX	NNP
cord-347298-7kqrl3rv	763	5	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	763	6	,	,	,
cord-347298-7kqrl3rv	763	7	which	which	WDT
cord-347298-7kqrl3rv	763	8	are	be	VBP
cord-347298-7kqrl3rv	763	9	the	the	DT
cord-347298-7kqrl3rv	763	10	products	product	NNS
cord-347298-7kqrl3rv	763	11	of	of	IN
cord-347298-7kqrl3rv	763	12	different	different	JJ
cord-347298-7kqrl3rv	763	13	genes	gene	NNS
cord-347298-7kqrl3rv	763	14	:	:	:
cord-347298-7kqrl3rv	763	15	the	the	DT
cord-347298-7kqrl3rv	763	16	constitutively	constitutively	RB
cord-347298-7kqrl3rv	763	17	expressed	express	VBN
cord-347298-7kqrl3rv	763	18	COX1	COX1	NNP
cord-347298-7kqrl3rv	763	19	and	and	CC
cord-347298-7kqrl3rv	763	20	an	an	DT
cord-347298-7kqrl3rv	763	21	inflammation	inflammation	NN
cord-347298-7kqrl3rv	763	22	-	-	HYPH
cord-347298-7kqrl3rv	763	23	induced	induce	VBN
cord-347298-7kqrl3rv	763	24	form	form	NN
cord-347298-7kqrl3rv	763	25	,	,	,
cord-347298-7kqrl3rv	763	26	COX2	COX2	NNP
cord-347298-7kqrl3rv	763	27	(	(	-LRB-
cord-347298-7kqrl3rv	763	28	Table	Table	NNP
cord-347298-7kqrl3rv	763	29	2	2	CD
cord-347298-7kqrl3rv	763	30	)	)	-RRB-
cord-347298-7kqrl3rv	763	31	(	(	-LRB-
cord-347298-7kqrl3rv	763	32	Smith	Smith	NNP
cord-347298-7kqrl3rv	763	33	et	et	NNP
cord-347298-7kqrl3rv	763	34	al	al	NNP
cord-347298-7kqrl3rv	763	35	.	.	.
cord-347298-7kqrl3rv	764	1	2000	2000	CD
cord-347298-7kqrl3rv	765	1	;	;	:
cord-347298-7kqrl3rv	765	2	Tanabe	Tanabe	NNP
cord-347298-7kqrl3rv	765	3	and	and	CC
cord-347298-7kqrl3rv	765	4	Tohnai	Tohnai	NNP
cord-347298-7kqrl3rv	765	5	2002	2002	CD
cord-347298-7kqrl3rv	765	6	)	)	-RRB-
cord-347298-7kqrl3rv	765	7	.	.	.
cord-347298-7kqrl3rv	766	1	While	while	IN
cord-347298-7kqrl3rv	766	2	conversion	conversion	NN
cord-347298-7kqrl3rv	766	3	of	of	IN
cord-347298-7kqrl3rv	766	4	arachidonic	arachidonic	JJ
cord-347298-7kqrl3rv	766	5	acid	acid	NN
cord-347298-7kqrl3rv	766	6	to	to	IN
cord-347298-7kqrl3rv	766	7	the	the	DT
cord-347298-7kqrl3rv	766	8	prostanoid	prostanoid	JJ
cord-347298-7kqrl3rv	766	9	precursor	precursor	NN
cord-347298-7kqrl3rv	766	10	PGH	PGH	NNP
cord-347298-7kqrl3rv	766	11	2	2	CD
cord-347298-7kqrl3rv	766	12	by	by	IN
cord-347298-7kqrl3rv	766	13	COX	COX	NNP
cord-347298-7kqrl3rv	766	14	is	be	VBZ
cord-347298-7kqrl3rv	766	15	the	the	DT
cord-347298-7kqrl3rv	766	16	rate	rate	NN
cord-347298-7kqrl3rv	766	17	-	-	HYPH
cord-347298-7kqrl3rv	766	18	limiting	limit	VBG
cord-347298-7kqrl3rv	766	19	step	step	NN
cord-347298-7kqrl3rv	766	20	,	,	,
cord-347298-7kqrl3rv	766	21	production	production	NN
cord-347298-7kqrl3rv	766	22	of	of	IN
cord-347298-7kqrl3rv	766	23	specific	specific	JJ
cord-347298-7kqrl3rv	766	24	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	766	25	depends	depend	VBZ
cord-347298-7kqrl3rv	766	26	on	on	IN
cord-347298-7kqrl3rv	766	27	the	the	DT
cord-347298-7kqrl3rv	766	28	activity	activity	NN
cord-347298-7kqrl3rv	766	29	of	of	IN
cord-347298-7kqrl3rv	766	30	the	the	DT
cord-347298-7kqrl3rv	766	31	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	766	32	synthases	synthase	NNS
cord-347298-7kqrl3rv	766	33	,	,	,
cord-347298-7kqrl3rv	766	34	that	that	RB
cord-347298-7kqrl3rv	766	35	is	is	RB
cord-347298-7kqrl3rv	766	36	,	,	,
cord-347298-7kqrl3rv	766	37	PGE	PGE	NNP
cord-347298-7kqrl3rv	766	38	synthase	synthase	NN
cord-347298-7kqrl3rv	766	39	(	(	-LRB-
cord-347298-7kqrl3rv	766	40	PGES	PGES	NNP
cord-347298-7kqrl3rv	766	41	)	)	-RRB-
cord-347298-7kqrl3rv	766	42	,	,	,
cord-347298-7kqrl3rv	766	43	PGIS	PGIS	NNP
cord-347298-7kqrl3rv	766	44	,	,	,
cord-347298-7kqrl3rv	766	45	PGDS	PGDS	NNP
cord-347298-7kqrl3rv	766	46	,	,	,
cord-347298-7kqrl3rv	766	47	PGFS	PGFS	NNP
cord-347298-7kqrl3rv	766	48	,	,	,
cord-347298-7kqrl3rv	766	49	and	and	CC
cord-347298-7kqrl3rv	766	50	thromboxane	thromboxane	NN
cord-347298-7kqrl3rv	766	51	A	a	DT
cord-347298-7kqrl3rv	766	52	synthase	synthase	NN
cord-347298-7kqrl3rv	766	53	(	(	-LRB-
cord-347298-7kqrl3rv	766	54	TxAS	txas	NN
cord-347298-7kqrl3rv	766	55	)	)	-RRB-
cord-347298-7kqrl3rv	767	1	(	(	-LRB-
cord-347298-7kqrl3rv	767	2	Helliwell	Helliwell	NNP
cord-347298-7kqrl3rv	767	3	et	et	FW
cord-347298-7kqrl3rv	767	4	al	al	NNP
cord-347298-7kqrl3rv	767	5	.	.	.
cord-347298-7kqrl3rv	768	1	2004	2004	CD
cord-347298-7kqrl3rv	768	2	;	;	:
cord-347298-7kqrl3rv	768	3	Ueno	Ueno	NNP
cord-347298-7kqrl3rv	768	4	et	et	NNP
cord-347298-7kqrl3rv	768	5	al	al	NNP
cord-347298-7kqrl3rv	768	6	.	.	NNP
cord-347298-7kqrl3rv	768	7	2005	2005	CD
cord-347298-7kqrl3rv	768	8	)	)	-RRB-
cord-347298-7kqrl3rv	768	9	.	.	.
cord-347298-7kqrl3rv	769	1	Each	each	DT
cord-347298-7kqrl3rv	769	2	prostanoid	prostanoid	FW
cord-347298-7kqrl3rv	769	3	acts	act	VBZ
cord-347298-7kqrl3rv	769	4	via	via	IN
cord-347298-7kqrl3rv	769	5	one	one	CD
cord-347298-7kqrl3rv	769	6	or	or	CC
cord-347298-7kqrl3rv	769	7	more	more	RBR
cord-347298-7kqrl3rv	769	8	specific	specific	JJ
cord-347298-7kqrl3rv	769	9	receptors	receptor	NNS
cord-347298-7kqrl3rv	769	10	to	to	TO
cord-347298-7kqrl3rv	769	11	regulate	regulate	VB
cord-347298-7kqrl3rv	769	12	cell	cell	NN
cord-347298-7kqrl3rv	769	13	growth	growth	NN
cord-347298-7kqrl3rv	769	14	,	,	,
cord-347298-7kqrl3rv	769	15	vascular	vascular	JJ
cord-347298-7kqrl3rv	769	16	smooth	smooth	JJ
cord-347298-7kqrl3rv	769	17	muscle	muscle	NN
cord-347298-7kqrl3rv	769	18	constriction	constriction	NN
cord-347298-7kqrl3rv	769	19	or	or	CC
cord-347298-7kqrl3rv	769	20	relaxation	relaxation	NN
cord-347298-7kqrl3rv	769	21	,	,	,
cord-347298-7kqrl3rv	769	22	vascular	vascular	JJ
cord-347298-7kqrl3rv	769	23	permeability	permeability	NN
cord-347298-7kqrl3rv	769	24	,	,	,
cord-347298-7kqrl3rv	769	25	and	and	CC
cord-347298-7kqrl3rv	769	26	immune	immune	JJ
cord-347298-7kqrl3rv	769	27	cell	cell	NN
cord-347298-7kqrl3rv	769	28	activity	activity	NN
cord-347298-7kqrl3rv	770	1	(	(	-LRB-
cord-347298-7kqrl3rv	770	2	Bos	Bos	NNP
cord-347298-7kqrl3rv	770	3	et	et	NNP
cord-347298-7kqrl3rv	770	4	al	al	NNP
cord-347298-7kqrl3rv	770	5	.	.	.
cord-347298-7kqrl3rv	771	1	2004	2004	CD
cord-347298-7kqrl3rv	771	2	;	;	:
cord-347298-7kqrl3rv	771	3	Hata	Hata	NNP
cord-347298-7kqrl3rv	771	4	et	et	NNP
cord-347298-7kqrl3rv	771	5	al	al	NNP
cord-347298-7kqrl3rv	771	6	.	.	NNP
cord-347298-7kqrl3rv	771	7	1990	1990	CD
cord-347298-7kqrl3rv	771	8	)	)	-RRB-
cord-347298-7kqrl3rv	771	9	.	.	.
cord-347298-7kqrl3rv	772	1	Several	several	JJ
cord-347298-7kqrl3rv	772	2	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	772	3	exert	exert	VBP
cord-347298-7kqrl3rv	772	4	both	both	DT
cord-347298-7kqrl3rv	772	5	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	772	6	and	and	CC
cord-347298-7kqrl3rv	772	7	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	772	8	actions	action	NNS
cord-347298-7kqrl3rv	772	9	through	through	IN
cord-347298-7kqrl3rv	772	10	different	different	JJ
cord-347298-7kqrl3rv	772	11	receptor	receptor	NN
cord-347298-7kqrl3rv	772	12	interactions	interaction	NNS
cord-347298-7kqrl3rv	772	13	,	,	,
cord-347298-7kqrl3rv	772	14	or	or	CC
cord-347298-7kqrl3rv	772	15	through	through	IN
cord-347298-7kqrl3rv	772	16	metabolism	metabolism	NN
cord-347298-7kqrl3rv	772	17	to	to	IN
cord-347298-7kqrl3rv	772	18	other	other	JJ
cord-347298-7kqrl3rv	772	19	active	active	JJ
cord-347298-7kqrl3rv	772	20	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	772	21	metabolites	metabolite	NNS
cord-347298-7kqrl3rv	772	22	,	,	,
cord-347298-7kqrl3rv	772	23	such	such	JJ
cord-347298-7kqrl3rv	772	24	as	as	IN
cord-347298-7kqrl3rv	772	25	15-deoxy	15-deoxy	CD
cord-347298-7kqrl3rv	772	26	-	-	HYPH
cord-347298-7kqrl3rv	772	27	PGJ	PGJ	NNP
cord-347298-7kqrl3rv	772	28	2	2	CD
cord-347298-7kqrl3rv	772	29	,	,	,
cord-347298-7kqrl3rv	772	30	a	a	DT
cord-347298-7kqrl3rv	772	31	ligand	ligand	NN
cord-347298-7kqrl3rv	772	32	for	for	IN
cord-347298-7kqrl3rv	772	33	the	the	DT
cord-347298-7kqrl3rv	772	34	peroxisome	peroxisome	NN
cord-347298-7kqrl3rv	772	35	proliferator	proliferator	NN
cord-347298-7kqrl3rv	772	36	-	-	HYPH
cord-347298-7kqrl3rv	772	37	activated	activate	VBN
cord-347298-7kqrl3rv	772	38	receptor	receptor	NN
cord-347298-7kqrl3rv	772	39	(	(	-LRB-
cord-347298-7kqrl3rv	772	40	PPAR	PPAR	NNP
cord-347298-7kqrl3rv	772	41	)	)	-RRB-
cord-347298-7kqrl3rv	773	1	(	(	-LRB-
cord-347298-7kqrl3rv	773	2	Jiang	Jiang	NNP
cord-347298-7kqrl3rv	773	3	et	et	FW
cord-347298-7kqrl3rv	773	4	al	al	NNP
cord-347298-7kqrl3rv	773	5	.	.	NNP
cord-347298-7kqrl3rv	773	6	1998	1998	CD
cord-347298-7kqrl3rv	773	7	)	)	-RRB-
cord-347298-7kqrl3rv	773	8	.	.	.
cord-347298-7kqrl3rv	774	1	An	an	DT
cord-347298-7kqrl3rv	774	2	alternative	alternative	JJ
cord-347298-7kqrl3rv	774	3	synthetic	synthetic	JJ
cord-347298-7kqrl3rv	774	4	pathway	pathway	NN
cord-347298-7kqrl3rv	774	5	,	,	,
cord-347298-7kqrl3rv	774	6	catalyzed	catalyze	VBN
cord-347298-7kqrl3rv	774	7	by	by	IN
cord-347298-7kqrl3rv	774	8	the	the	DT
cord-347298-7kqrl3rv	774	9	lipoxygenases	lipoxygenase	NNS
cord-347298-7kqrl3rv	774	10	,	,	,
cord-347298-7kqrl3rv	774	11	converts	convert	VBZ
cord-347298-7kqrl3rv	774	12	arachidonic	arachidonic	JJ
cord-347298-7kqrl3rv	774	13	acid	acid	NN
cord-347298-7kqrl3rv	774	14	to	to	IN
cord-347298-7kqrl3rv	774	15	the	the	DT
cord-347298-7kqrl3rv	774	16	related	related	JJ
cord-347298-7kqrl3rv	774	17	leukotrienes	leukotriene	NNS
cord-347298-7kqrl3rv	774	18	and	and	CC
cord-347298-7kqrl3rv	774	19	lipoxins	lipoxin	NNS
cord-347298-7kqrl3rv	774	20	,	,	,
cord-347298-7kqrl3rv	774	21	which	which	WDT
cord-347298-7kqrl3rv	774	22	also	also	RB
cord-347298-7kqrl3rv	774	23	possess	possess	VBP
cord-347298-7kqrl3rv	774	24	diverse	diverse	JJ
cord-347298-7kqrl3rv	774	25	metabolic	metabolic	JJ
cord-347298-7kqrl3rv	774	26	,	,	,
cord-347298-7kqrl3rv	774	27	vascular	vascular	JJ
cord-347298-7kqrl3rv	774	28	,	,	,
cord-347298-7kqrl3rv	774	29	and	and	CC
cord-347298-7kqrl3rv	774	30	inflammation	inflammation	NN
cord-347298-7kqrl3rv	774	31	-	-	HYPH
cord-347298-7kqrl3rv	774	32	regulating	regulate	VBG
cord-347298-7kqrl3rv	774	33	actions	action	NNS
cord-347298-7kqrl3rv	775	1	(	(	-LRB-
cord-347298-7kqrl3rv	775	2	Samuelsson	Samuelsson	NNP
cord-347298-7kqrl3rv	775	3	et	et	NNP
cord-347298-7kqrl3rv	775	4	al	al	NNP
cord-347298-7kqrl3rv	775	5	.	.	NNP
cord-347298-7kqrl3rv	775	6	1987	1987	CD
cord-347298-7kqrl3rv	775	7	;	;	:
cord-347298-7kqrl3rv	775	8	Takano	Takano	NNP
cord-347298-7kqrl3rv	775	9	et	et	NNP
cord-347298-7kqrl3rv	775	10	al	al	NNP
cord-347298-7kqrl3rv	775	11	.	.	.
cord-347298-7kqrl3rv	775	12	1997	1997	CD
cord-347298-7kqrl3rv	775	13	)	)	-RRB-
cord-347298-7kqrl3rv	775	14	.	.	.
cord-347298-7kqrl3rv	776	1	Most	Most	JJS
cord-347298-7kqrl3rv	776	2	of	of	IN
cord-347298-7kqrl3rv	776	3	the	the	DT
cord-347298-7kqrl3rv	776	4	enzymes	enzyme	NNS
cord-347298-7kqrl3rv	776	5	responsible	responsible	JJ
cord-347298-7kqrl3rv	776	6	for	for	IN
cord-347298-7kqrl3rv	776	7	prostanoid	prostanoid	JJ
cord-347298-7kqrl3rv	776	8	production	production	NN
cord-347298-7kqrl3rv	776	9	are	be	VBP
cord-347298-7kqrl3rv	776	10	ubiquitously	ubiquitously	RB
cord-347298-7kqrl3rv	776	11	expressed	express	VBN
cord-347298-7kqrl3rv	776	12	,	,	,
cord-347298-7kqrl3rv	776	13	and	and	CC
cord-347298-7kqrl3rv	776	14	this	this	DT
cord-347298-7kqrl3rv	776	15	includes	include	VBZ
cord-347298-7kqrl3rv	776	16	the	the	DT
cord-347298-7kqrl3rv	776	17	male	male	JJ
cord-347298-7kqrl3rv	776	18	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	776	19	tract	tract	NN
cord-347298-7kqrl3rv	776	20	(	(	-LRB-
cord-347298-7kqrl3rv	776	21	Gerena	Gerena	NNP
cord-347298-7kqrl3rv	776	22	et	et	FW
cord-347298-7kqrl3rv	776	23	al	al	NNP
cord-347298-7kqrl3rv	776	24	.	.	.
cord-347298-7kqrl3rv	776	25	2000	2000	CD
cord-347298-7kqrl3rv	776	26	;	;	:
cord-347298-7kqrl3rv	776	27	Lazarus	Lazarus	NNP
cord-347298-7kqrl3rv	776	28	et	et	NNP
cord-347298-7kqrl3rv	776	29	al	al	NNP
cord-347298-7kqrl3rv	776	30	.	.	.
cord-347298-7kqrl3rv	776	31	2002	2002	CD
cord-347298-7kqrl3rv	776	32	;	;	:
cord-347298-7kqrl3rv	776	33	Takahashi	Takahashi	NNP
cord-347298-7kqrl3rv	776	34	et	et	FW
cord-347298-7kqrl3rv	776	35	al	al	NNP
cord-347298-7kqrl3rv	776	36	.	.	NNP
cord-347298-7kqrl3rv	776	37	1995	1995	CD
cord-347298-7kqrl3rv	776	38	;	;	:
cord-347298-7kqrl3rv	776	39	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	776	40	et	et	NNP
cord-347298-7kqrl3rv	776	41	al	al	NNP
cord-347298-7kqrl3rv	776	42	.	.	NNP
cord-347298-7kqrl3rv	776	43	2007	2007	CD
cord-347298-7kqrl3rv	776	44	)	)	-RRB-
cord-347298-7kqrl3rv	776	45	.	.	.
cord-347298-7kqrl3rv	777	1	In	in	IN
cord-347298-7kqrl3rv	777	2	fact	fact	NN
cord-347298-7kqrl3rv	777	3	,	,	,
cord-347298-7kqrl3rv	777	4	the	the	DT
cord-347298-7kqrl3rv	777	5	levels	level	NNS
cord-347298-7kqrl3rv	777	6	of	of	IN
cord-347298-7kqrl3rv	777	7	E	e	NN
cord-347298-7kqrl3rv	777	8	series	series	NN
cord-347298-7kqrl3rv	777	9	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	777	10	in	in	IN
cord-347298-7kqrl3rv	777	11	human	human	JJ
cord-347298-7kqrl3rv	777	12	seminal	seminal	JJ
cord-347298-7kqrl3rv	777	13	plasma	plasma	NN
cord-347298-7kqrl3rv	777	14	are	be	VBP
cord-347298-7kqrl3rv	777	15	remarkably	remarkably	RB
cord-347298-7kqrl3rv	777	16	high	high	JJ
cord-347298-7kqrl3rv	777	17	(	(	-LRB-
cord-347298-7kqrl3rv	777	18	Cooper	Cooper	NNP
cord-347298-7kqrl3rv	777	19	and	and	CC
cord-347298-7kqrl3rv	777	20	Kelly	Kelly	NNP
cord-347298-7kqrl3rv	777	21	1975	1975	CD
cord-347298-7kqrl3rv	777	22	)	)	-RRB-
cord-347298-7kqrl3rv	777	23	.	.	.
cord-347298-7kqrl3rv	778	1	Most	Most	JJS
cord-347298-7kqrl3rv	778	2	testicular	testicular	NN
cord-347298-7kqrl3rv	778	3	cells	cell	NNS
cord-347298-7kqrl3rv	778	4	express	express	VBP
cord-347298-7kqrl3rv	778	5	both	both	DT
cord-347298-7kqrl3rv	778	6	COX	COX	NNP
cord-347298-7kqrl3rv	778	7	forms	form	NNS
cord-347298-7kqrl3rv	778	8	,	,	,
cord-347298-7kqrl3rv	778	9	and	and	CC
cord-347298-7kqrl3rv	778	10	possess	possess	VB
cord-347298-7kqrl3rv	778	11	the	the	DT
cord-347298-7kqrl3rv	778	12	capacity	capacity	NN
cord-347298-7kqrl3rv	778	13	to	to	TO
cord-347298-7kqrl3rv	778	14	produce	produce	VB
cord-347298-7kqrl3rv	778	15	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	778	16	in	in	IN
cord-347298-7kqrl3rv	778	17	vitro	vitro	FW
cord-347298-7kqrl3rv	779	1	(	(	-LRB-
cord-347298-7kqrl3rv	779	2	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	779	3	et	et	NNP
cord-347298-7kqrl3rv	779	4	al	al	NNP
cord-347298-7kqrl3rv	779	5	.	.	NNP
cord-347298-7kqrl3rv	779	6	2007	2007	CD
cord-347298-7kqrl3rv	779	7	)	)	-RRB-
cord-347298-7kqrl3rv	779	8	,	,	,
cord-347298-7kqrl3rv	779	9	although	although	IN
cord-347298-7kqrl3rv	779	10	there	there	EX
cord-347298-7kqrl3rv	779	11	appear	appear	VBP
cord-347298-7kqrl3rv	779	12	to	to	TO
cord-347298-7kqrl3rv	779	13	be	be	VB
cord-347298-7kqrl3rv	779	14	cell	cell	NN
cord-347298-7kqrl3rv	779	15	type	type	NN
cord-347298-7kqrl3rv	779	16	-	-	HYPH
cord-347298-7kqrl3rv	779	17	specific	specific	JJ
cord-347298-7kqrl3rv	779	18	and	and	CC
cord-347298-7kqrl3rv	779	19	species	species	NN
cord-347298-7kqrl3rv	779	20	-	-	HYPH
cord-347298-7kqrl3rv	779	21	specific	specific	JJ
cord-347298-7kqrl3rv	779	22	differences	difference	NNS
cord-347298-7kqrl3rv	779	23	in	in	IN
cord-347298-7kqrl3rv	779	24	the	the	DT
cord-347298-7kqrl3rv	779	25	relative	relative	JJ
cord-347298-7kqrl3rv	779	26	levels	level	NNS
cord-347298-7kqrl3rv	779	27	of	of	IN
cord-347298-7kqrl3rv	779	28	expression	expression	NN
cord-347298-7kqrl3rv	779	29	(	(	-LRB-
cord-347298-7kqrl3rv	779	30	Balaji	Balaji	NNP
cord-347298-7kqrl3rv	779	31	et	et	NNP
cord-347298-7kqrl3rv	779	32	al	al	NNP
cord-347298-7kqrl3rv	779	33	.	.	NNP
cord-347298-7kqrl3rv	779	34	2007	2007	CD
cord-347298-7kqrl3rv	779	35	;	;	:
cord-347298-7kqrl3rv	779	36	Frungieri	Frungieri	NNP
cord-347298-7kqrl3rv	779	37	et	et	FW
cord-347298-7kqrl3rv	779	38	al	al	NNP
cord-347298-7kqrl3rv	779	39	.	.	.
cord-347298-7kqrl3rv	780	1	2006	2006	CD
cord-347298-7kqrl3rv	780	2	;	;	:
cord-347298-7kqrl3rv	780	3	Lazarus	Lazarus	NNP
cord-347298-7kqrl3rv	780	4	et	et	NNP
cord-347298-7kqrl3rv	780	5	al	al	NNP
cord-347298-7kqrl3rv	780	6	.	.	.
cord-347298-7kqrl3rv	780	7	2004	2004	CD
cord-347298-7kqrl3rv	780	8	)	)	-RRB-
cord-347298-7kqrl3rv	780	9	.	.	.
cord-347298-7kqrl3rv	781	1	In	in	IN
cord-347298-7kqrl3rv	781	2	the	the	DT
cord-347298-7kqrl3rv	781	3	normal	normal	JJ
cord-347298-7kqrl3rv	781	4	rat	rat	NN
cord-347298-7kqrl3rv	781	5	testis	testis	NN
cord-347298-7kqrl3rv	781	6	,	,	,
cord-347298-7kqrl3rv	781	7	COX2	COX2	NNP
cord-347298-7kqrl3rv	781	8	is	be	VBZ
cord-347298-7kqrl3rv	781	9	responsible	responsible	JJ
cord-347298-7kqrl3rv	781	10	for	for	IN
cord-347298-7kqrl3rv	781	11	the	the	DT
cord-347298-7kqrl3rv	781	12	majority	majority	NN
cord-347298-7kqrl3rv	781	13	of	of	IN
cord-347298-7kqrl3rv	781	14	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	781	15	production	production	NN
cord-347298-7kqrl3rv	782	1	(	(	-LRB-
cord-347298-7kqrl3rv	782	2	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	782	3	et	et	NNP
cord-347298-7kqrl3rv	782	4	al	al	NNP
cord-347298-7kqrl3rv	782	5	.	.	NNP
cord-347298-7kqrl3rv	782	6	2007	2007	CD
cord-347298-7kqrl3rv	782	7	)	)	-RRB-
cord-347298-7kqrl3rv	782	8	,	,	,
cord-347298-7kqrl3rv	782	9	although	although	IN
cord-347298-7kqrl3rv	782	10	intratesticular	intratesticular	NNP
cord-347298-7kqrl3rv	782	11	PGE	PGE	NNP
cord-347298-7kqrl3rv	782	12	2	2	CD
cord-347298-7kqrl3rv	782	13	levels	level	NNS
cord-347298-7kqrl3rv	782	14	are	be	VBP
cord-347298-7kqrl3rv	782	15	only	only	RB
cord-347298-7kqrl3rv	782	16	marginally	marginally	RB
cord-347298-7kqrl3rv	782	17	affected	affect	VBN
cord-347298-7kqrl3rv	782	18	by	by	IN
cord-347298-7kqrl3rv	782	19	acute	acute	JJ
cord-347298-7kqrl3rv	782	20	inflammation	inflammation	NN
cord-347298-7kqrl3rv	783	1	(	(	-LRB-
cord-347298-7kqrl3rv	783	2	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	783	3	et	et	NNP
cord-347298-7kqrl3rv	783	4	al	al	NNP
cord-347298-7kqrl3rv	783	5	.	.	NNP
cord-347298-7kqrl3rv	783	6	2008	2008	CD
cord-347298-7kqrl3rv	783	7	)	)	-RRB-
cord-347298-7kqrl3rv	783	8	.	.	.
cord-347298-7kqrl3rv	784	1	This	this	DT
cord-347298-7kqrl3rv	784	2	is	be	VBZ
cord-347298-7kqrl3rv	784	3	probably	probably	RB
cord-347298-7kqrl3rv	784	4	due	due	JJ
cord-347298-7kqrl3rv	784	5	to	to	IN
cord-347298-7kqrl3rv	784	6	the	the	DT
cord-347298-7kqrl3rv	784	7	fact	fact	NN
cord-347298-7kqrl3rv	784	8	that	that	IN
cord-347298-7kqrl3rv	784	9	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	784	10	in	in	IN
cord-347298-7kqrl3rv	784	11	the	the	DT
cord-347298-7kqrl3rv	784	12	rat	rat	NN
cord-347298-7kqrl3rv	784	13	testis	testis	NN
cord-347298-7kqrl3rv	784	14	express	express	VB
cord-347298-7kqrl3rv	784	15	COX2	COX2	NNP
cord-347298-7kqrl3rv	784	16	at	at	IN
cord-347298-7kqrl3rv	784	17	very	very	RB
cord-347298-7kqrl3rv	784	18	low	low	JJ
cord-347298-7kqrl3rv	784	19	levels	level	NNS
cord-347298-7kqrl3rv	784	20	,	,	,
cord-347298-7kqrl3rv	784	21	but	but	CC
cord-347298-7kqrl3rv	784	22	are	be	VBP
cord-347298-7kqrl3rv	784	23	the	the	DT
cord-347298-7kqrl3rv	784	24	only	only	JJ
cord-347298-7kqrl3rv	784	25	testis	testis	NN
cord-347298-7kqrl3rv	784	26	cell	cell	NN
cord-347298-7kqrl3rv	784	27	type	type	NN
cord-347298-7kqrl3rv	784	28	to	to	TO
cord-347298-7kqrl3rv	784	29	respond	respond	VB
cord-347298-7kqrl3rv	784	30	to	to	IN
cord-347298-7kqrl3rv	784	31	an	an	DT
cord-347298-7kqrl3rv	784	32	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	784	33	stimulus	stimulus	NN
cord-347298-7kqrl3rv	784	34	with	with	IN
cord-347298-7kqrl3rv	784	35	a	a	DT
cord-347298-7kqrl3rv	784	36	significant	significant	JJ
cord-347298-7kqrl3rv	784	37	increase	increase	NN
cord-347298-7kqrl3rv	784	38	in	in	IN
cord-347298-7kqrl3rv	784	39	COX2	cox2	JJ
cord-347298-7kqrl3rv	784	40	activity	activity	NN
cord-347298-7kqrl3rv	785	1	(	(	-LRB-
cord-347298-7kqrl3rv	785	2	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	785	3	et	et	NNP
cord-347298-7kqrl3rv	785	4	al	al	NNP
cord-347298-7kqrl3rv	785	5	.	.	NNP
cord-347298-7kqrl3rv	785	6	2007	2007	CD
cord-347298-7kqrl3rv	785	7	)	)	-RRB-
cord-347298-7kqrl3rv	785	8	.	.	.
cord-347298-7kqrl3rv	786	1	These	these	DT
cord-347298-7kqrl3rv	786	2	data	datum	NNS
cord-347298-7kqrl3rv	786	3	point	point	NN
cord-347298-7kqrl3rv	786	4	toward	toward	IN
cord-347298-7kqrl3rv	786	5	a	a	DT
cord-347298-7kqrl3rv	786	6	previously	previously	RB
cord-347298-7kqrl3rv	786	7	unanticipated	unanticipated	JJ
cord-347298-7kqrl3rv	786	8	maintenance	maintenance	NN
cord-347298-7kqrl3rv	786	9	role	role	NN
cord-347298-7kqrl3rv	786	10	for	for	IN
cord-347298-7kqrl3rv	786	11	the	the	DT
cord-347298-7kqrl3rv	786	12	socalled	socalled	JJ
cord-347298-7kqrl3rv	786	13	inducible	inducible	JJ
cord-347298-7kqrl3rv	786	14	COX2	cox2	JJ
cord-347298-7kqrl3rv	786	15	enzyme	enzyme	NN
cord-347298-7kqrl3rv	786	16	in	in	IN
cord-347298-7kqrl3rv	786	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	786	18	function	function	NN
cord-347298-7kqrl3rv	786	19	,	,	,
cord-347298-7kqrl3rv	786	20	as	as	RB
cord-347298-7kqrl3rv	786	21	well	well	RB
cord-347298-7kqrl3rv	786	22	as	as	IN
cord-347298-7kqrl3rv	786	23	an	an	DT
cord-347298-7kqrl3rv	786	24	anomalous	anomalous	JJ
cord-347298-7kqrl3rv	786	25	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	786	26	response	response	NN
cord-347298-7kqrl3rv	786	27	of	of	IN
cord-347298-7kqrl3rv	786	28	testicular	testicular	JJ
cord-347298-7kqrl3rv	786	29	COX2	COX2	NNP
cord-347298-7kqrl3rv	786	30	,	,	,
cord-347298-7kqrl3rv	786	31	consistent	consistent	JJ
cord-347298-7kqrl3rv	786	32	with	with	IN
cord-347298-7kqrl3rv	786	33	an	an	DT
cord-347298-7kqrl3rv	786	34	altered	alter	VBN
cord-347298-7kqrl3rv	786	35	capacity	capacity	NN
cord-347298-7kqrl3rv	786	36	of	of	IN
cord-347298-7kqrl3rv	786	37	this	this	DT
cord-347298-7kqrl3rv	786	38	organ	organ	NN
cord-347298-7kqrl3rv	786	39	to	to	TO
cord-347298-7kqrl3rv	786	40	initiate	initiate	VB
cord-347298-7kqrl3rv	786	41	and	and	CC
cord-347298-7kqrl3rv	786	42	support	support	VB
cord-347298-7kqrl3rv	786	43	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	786	44	reactions	reaction	NNS
cord-347298-7kqrl3rv	786	45	.	.	.
cord-347298-7kqrl3rv	787	1	Fertility	fertility	NN
cord-347298-7kqrl3rv	787	2	is	be	VBZ
cord-347298-7kqrl3rv	787	3	retained	retain	VBN
cord-347298-7kqrl3rv	787	4	in	in	IN
cord-347298-7kqrl3rv	787	5	male	male	JJ
cord-347298-7kqrl3rv	787	6	mice	mouse	NNS
cord-347298-7kqrl3rv	787	7	lacking	lack	VBG
cord-347298-7kqrl3rv	787	8	either	either	CC
cord-347298-7kqrl3rv	787	9	COX1	cox1	JJ
cord-347298-7kqrl3rv	787	10	or	or	CC
cord-347298-7kqrl3rv	787	11	COX2	COX2	NNP
cord-347298-7kqrl3rv	787	12	,	,	,
cord-347298-7kqrl3rv	787	13	whereas	whereas	IN
cord-347298-7kqrl3rv	787	14	double	double	JJ
cord-347298-7kqrl3rv	787	15	deletions	deletion	NNS
cord-347298-7kqrl3rv	787	16	are	be	VBP
cord-347298-7kqrl3rv	787	17	lethal	lethal	JJ
cord-347298-7kqrl3rv	787	18	(	(	-LRB-
cord-347298-7kqrl3rv	787	19	Langenbach	Langenbach	NNP
cord-347298-7kqrl3rv	787	20	et	et	FW
cord-347298-7kqrl3rv	787	21	al	al	NNP
cord-347298-7kqrl3rv	787	22	.	.	.
cord-347298-7kqrl3rv	787	23	1999	1999	CD
cord-347298-7kqrl3rv	787	24	;	;	:
cord-347298-7kqrl3rv	787	25	Lim	Lim	NNP
cord-347298-7kqrl3rv	787	26	et	et	NNP
cord-347298-7kqrl3rv	787	27	al	al	NNP
cord-347298-7kqrl3rv	787	28	.	.	.
cord-347298-7kqrl3rv	788	1	1997	1997	CD
cord-347298-7kqrl3rv	788	2	;	;	:
cord-347298-7kqrl3rv	788	3	Sales	sale	NNS
cord-347298-7kqrl3rv	788	4	and	and	CC
cord-347298-7kqrl3rv	788	5	Jabbour	Jabbour	NNP
cord-347298-7kqrl3rv	788	6	2003	2003	CD
cord-347298-7kqrl3rv	788	7	)	)	-RRB-
cord-347298-7kqrl3rv	788	8	.	.	.
cord-347298-7kqrl3rv	789	1	Studies	study	NNS
cord-347298-7kqrl3rv	789	2	on	on	IN
cord-347298-7kqrl3rv	789	3	male	male	JJ
cord-347298-7kqrl3rv	789	4	fertility	fertility	NN
cord-347298-7kqrl3rv	789	5	and	and	CC
cord-347298-7kqrl3rv	789	6	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	789	7	using	use	VBG
cord-347298-7kqrl3rv	789	8	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	789	9	,	,	,
cord-347298-7kqrl3rv	789	10	or	or	CC
cord-347298-7kqrl3rv	789	11	nonsteroidal	nonsteroidal	JJ
cord-347298-7kqrl3rv	789	12	anti	anti	JJ
cord-347298-7kqrl3rv	789	13	-	-	JJ
cord-347298-7kqrl3rv	789	14	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	789	15	drugs	drug	NNS
cord-347298-7kqrl3rv	789	16	such	such	JJ
cord-347298-7kqrl3rv	789	17	as	as	IN
cord-347298-7kqrl3rv	789	18	aspirin	aspirin	NN
cord-347298-7kqrl3rv	789	19	and	and	CC
cord-347298-7kqrl3rv	789	20	indomethacin	indomethacin	NN
cord-347298-7kqrl3rv	789	21	,	,	,
cord-347298-7kqrl3rv	789	22	which	which	WDT
cord-347298-7kqrl3rv	789	23	act	act	VBP
cord-347298-7kqrl3rv	789	24	primarily	primarily	RB
cord-347298-7kqrl3rv	789	25	via	via	IN
cord-347298-7kqrl3rv	789	26	inhibition	inhibition	NN
cord-347298-7kqrl3rv	789	27	of	of	IN
cord-347298-7kqrl3rv	789	28	COX	COX	NNP
cord-347298-7kqrl3rv	789	29	activity	activity	NN
cord-347298-7kqrl3rv	789	30	,	,	,
cord-347298-7kqrl3rv	789	31	have	have	VBP
cord-347298-7kqrl3rv	789	32	produced	produce	VBN
cord-347298-7kqrl3rv	789	33	conflicting	conflicting	JJ
cord-347298-7kqrl3rv	789	34	conclusions	conclusion	NNS
cord-347298-7kqrl3rv	789	35	(	(	-LRB-
cord-347298-7kqrl3rv	789	36	Abbatiello	Abbatiello	NNP
cord-347298-7kqrl3rv	789	37	et	et	NNP
cord-347298-7kqrl3rv	789	38	al	al	NNP
cord-347298-7kqrl3rv	789	39	.	.	NNP
cord-347298-7kqrl3rv	789	40	1975	1975	CD
cord-347298-7kqrl3rv	789	41	;	;	:
cord-347298-7kqrl3rv	789	42	Biswas	Biswas	NNP
cord-347298-7kqrl3rv	789	43	et	et	NNP
cord-347298-7kqrl3rv	789	44	al	al	NNP
cord-347298-7kqrl3rv	789	45	.	.	.
cord-347298-7kqrl3rv	789	46	1978	1978	CD
cord-347298-7kqrl3rv	789	47	;	;	:
cord-347298-7kqrl3rv	789	48	Sanyal	Sanyal	NNP
cord-347298-7kqrl3rv	789	49	et	et	NNP
cord-347298-7kqrl3rv	789	50	al	al	NNP
cord-347298-7kqrl3rv	789	51	.	.	.
cord-347298-7kqrl3rv	789	52	1980	1980	CD
cord-347298-7kqrl3rv	789	53	;	;	:
cord-347298-7kqrl3rv	789	54	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	789	55	et	et	NNP
cord-347298-7kqrl3rv	789	56	al	al	NNP
cord-347298-7kqrl3rv	789	57	.	.	NNP
cord-347298-7kqrl3rv	789	58	2008	2008	CD
cord-347298-7kqrl3rv	789	59	)	)	-RRB-
cord-347298-7kqrl3rv	789	60	.	.	.
cord-347298-7kqrl3rv	790	1	These	these	DT
cord-347298-7kqrl3rv	790	2	diverse	diverse	JJ
cord-347298-7kqrl3rv	790	3	outcomes	outcome	NNS
cord-347298-7kqrl3rv	790	4	indicate	indicate	VBP
cord-347298-7kqrl3rv	790	5	the	the	DT
cord-347298-7kqrl3rv	790	6	complexity	complexity	NN
cord-347298-7kqrl3rv	790	7	of	of	IN
cord-347298-7kqrl3rv	790	8	the	the	DT
cord-347298-7kqrl3rv	790	9	roles	role	NNS
cord-347298-7kqrl3rv	790	10	of	of	IN
cord-347298-7kqrl3rv	790	11	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	790	12	in	in	IN
cord-347298-7kqrl3rv	790	13	controlling	control	VBG
cord-347298-7kqrl3rv	790	14	various	various	JJ
cord-347298-7kqrl3rv	790	15	aspects	aspect	NNS
cord-347298-7kqrl3rv	790	16	of	of	IN
cord-347298-7kqrl3rv	790	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	790	18	function	function	NN
cord-347298-7kqrl3rv	790	19	.	.	.
cord-347298-7kqrl3rv	791	1	Prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	791	2	,	,	,
cord-347298-7kqrl3rv	791	3	particularly	particularly	RB
cord-347298-7kqrl3rv	791	4	PGE	PGE	NNP
cord-347298-7kqrl3rv	791	5	2	2	CD
cord-347298-7kqrl3rv	791	6	and	and	CC
cord-347298-7kqrl3rv	791	7	PGF	PGF	NNP
cord-347298-7kqrl3rv	791	8	2	2	CD
cord-347298-7kqrl3rv	791	9	,	,	,
cord-347298-7kqrl3rv	791	10	have	have	VBP
cord-347298-7kqrl3rv	791	11	been	be	VBN
cord-347298-7kqrl3rv	791	12	implicated	implicate	VBN
cord-347298-7kqrl3rv	791	13	in	in	IN
cord-347298-7kqrl3rv	791	14	the	the	DT
cord-347298-7kqrl3rv	791	15	control	control	NN
cord-347298-7kqrl3rv	791	16	of	of	IN
cord-347298-7kqrl3rv	791	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	791	18	cell	cell	NN
cord-347298-7kqrl3rv	791	19	development	development	NN
cord-347298-7kqrl3rv	791	20	in	in	IN
cord-347298-7kqrl3rv	791	21	the	the	DT
cord-347298-7kqrl3rv	791	22	immature	immature	JJ
cord-347298-7kqrl3rv	791	23	testis	testis	NN
cord-347298-7kqrl3rv	791	24	,	,	,
cord-347298-7kqrl3rv	791	25	production	production	NN
cord-347298-7kqrl3rv	791	26	of	of	IN
cord-347298-7kqrl3rv	791	27	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	791	28	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	791	29	by	by	IN
cord-347298-7kqrl3rv	791	30	the	the	DT
cord-347298-7kqrl3rv	791	31	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	791	32	and	and	CC
cord-347298-7kqrl3rv	791	33	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	791	34	cells	cell	NNS
cord-347298-7kqrl3rv	791	35	,	,	,
cord-347298-7kqrl3rv	791	36	autoregulation	autoregulation	NN
cord-347298-7kqrl3rv	791	37	of	of	IN
cord-347298-7kqrl3rv	791	38	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	791	39	in	in	IN
cord-347298-7kqrl3rv	791	40	the	the	DT
cord-347298-7kqrl3rv	791	41	adult	adult	NN
cord-347298-7kqrl3rv	791	42	,	,	,
cord-347298-7kqrl3rv	791	43	and	and	CC
cord-347298-7kqrl3rv	791	44	the	the	DT
cord-347298-7kqrl3rv	791	45	decline	decline	NN
cord-347298-7kqrl3rv	791	46	in	in	IN
cord-347298-7kqrl3rv	791	47	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	791	48	cell	cell	NN
cord-347298-7kqrl3rv	791	49	function	function	NN
cord-347298-7kqrl3rv	791	50	that	that	WDT
cord-347298-7kqrl3rv	791	51	occurs	occur	VBZ
cord-347298-7kqrl3rv	791	52	during	during	IN
cord-347298-7kqrl3rv	791	53	aging	age	VBG
cord-347298-7kqrl3rv	791	54	(	(	-LRB-
cord-347298-7kqrl3rv	791	55	Baker	Baker	NNP
cord-347298-7kqrl3rv	791	56	and	and	CC
cord-347298-7kqrl3rv	791	57	O'Shaughnessy	O'Shaughnessy	NNP
cord-347298-7kqrl3rv	791	58	2001	2001	CD
cord-347298-7kqrl3rv	791	59	;	;	:
cord-347298-7kqrl3rv	791	60	Cooke	Cooke	NNP
cord-347298-7kqrl3rv	791	61	et	et	NNP
cord-347298-7kqrl3rv	791	62	al	al	NNP
cord-347298-7kqrl3rv	791	63	.	.	.
cord-347298-7kqrl3rv	791	64	1991	1991	CD
cord-347298-7kqrl3rv	792	1	;	;	:
cord-347298-7kqrl3rv	792	2	Haour	Haour	NNP
cord-347298-7kqrl3rv	792	3	et	et	NNP
cord-347298-7kqrl3rv	792	4	al	al	NNP
cord-347298-7kqrl3rv	792	5	.	.	.
cord-347298-7kqrl3rv	792	6	1979	1979	CD
cord-347298-7kqrl3rv	793	1	;	;	:
cord-347298-7kqrl3rv	793	2	Ishikawa	Ishikawa	NNP
cord-347298-7kqrl3rv	793	3	et	et	NNP
cord-347298-7kqrl3rv	793	4	al	al	NNP
cord-347298-7kqrl3rv	793	5	.	.	NNP
cord-347298-7kqrl3rv	793	6	2005	2005	CD
cord-347298-7kqrl3rv	793	7	;	;	.
cord-347298-7kqrl3rv	794	1	Walch	Walch	NNP
cord-347298-7kqrl3rv	794	2	and	and	CC
cord-347298-7kqrl3rv	794	3	Morris	Morris	NNP
cord-347298-7kqrl3rv	794	4	2002	2002	CD
cord-347298-7kqrl3rv	794	5	;	;	:
cord-347298-7kqrl3rv	794	6	Wang	Wang	NNP
cord-347298-7kqrl3rv	794	7	et	et	NNP
cord-347298-7kqrl3rv	794	8	al	al	NNP
cord-347298-7kqrl3rv	794	9	.	.	NNP
cord-347298-7kqrl3rv	794	10	2005	2005	CD
cord-347298-7kqrl3rv	794	11	)	)	-RRB-
cord-347298-7kqrl3rv	794	12	.	.	.
cord-347298-7kqrl3rv	795	1	Production	production	NN
cord-347298-7kqrl3rv	795	2	of	of	IN
cord-347298-7kqrl3rv	795	3	PGE	PGE	NNP
cord-347298-7kqrl3rv	795	4	2	2	CD
cord-347298-7kqrl3rv	795	5	and	and	CC
cord-347298-7kqrl3rv	795	6	PGF	PGF	NNP
cord-347298-7kqrl3rv	795	7	2	2	CD
cord-347298-7kqrl3rv	795	8	by	by	IN
cord-347298-7kqrl3rv	795	9	COX2	COX2	NNP
cord-347298-7kqrl3rv	795	10	also	also	RB
cord-347298-7kqrl3rv	795	11	mediates	mediate	VBZ
cord-347298-7kqrl3rv	795	12	the	the	DT
cord-347298-7kqrl3rv	795	13	effects	effect	NNS
cord-347298-7kqrl3rv	795	14	of	of	IN
cord-347298-7kqrl3rv	795	15	IL1	IL1	NNP
cord-347298-7kqrl3rv	795	16	on	on	IN
cord-347298-7kqrl3rv	795	17	protein	protein	NN
cord-347298-7kqrl3rv	795	18	and	and	CC
cord-347298-7kqrl3rv	795	19	lipid	lipid	NN
cord-347298-7kqrl3rv	795	20	regulation	regulation	NN
cord-347298-7kqrl3rv	795	21	by	by	IN
cord-347298-7kqrl3rv	795	22	the	the	DT
cord-347298-7kqrl3rv	795	23	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	795	24	cell	cell	NN
cord-347298-7kqrl3rv	795	25	involved	involve	VBN
cord-347298-7kqrl3rv	795	26	in	in	IN
cord-347298-7kqrl3rv	795	27	supporting	support	VBG
cord-347298-7kqrl3rv	795	28	Figure	figure	NN
cord-347298-7kqrl3rv	795	29	3	3	CD
cord-347298-7kqrl3rv	795	30	Prostanoid	Prostanoid	NNP
cord-347298-7kqrl3rv	795	31	and	and	CC
cord-347298-7kqrl3rv	795	32	lysophosphatidylcholine	lysophosphatidylcholine	NNP
cord-347298-7kqrl3rv	795	33	synthesis	synthesis	NN
cord-347298-7kqrl3rv	795	34	and	and	CC
cord-347298-7kqrl3rv	795	35	targets	target	NNS
cord-347298-7kqrl3rv	795	36	.	.	.
cord-347298-7kqrl3rv	796	1	Synthesis	synthesis	NN
cord-347298-7kqrl3rv	796	2	of	of	IN
cord-347298-7kqrl3rv	796	3	the	the	DT
cord-347298-7kqrl3rv	796	4	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	796	5	commences	commence	VBZ
cord-347298-7kqrl3rv	796	6	through	through	IN
cord-347298-7kqrl3rv	796	7	the	the	DT
cord-347298-7kqrl3rv	796	8	action	action	NN
cord-347298-7kqrl3rv	796	9	of	of	IN
cord-347298-7kqrl3rv	796	10	phospholipase	phospholipase	NN
cord-347298-7kqrl3rv	796	11	A	a	DT
cord-347298-7kqrl3rv	796	12	2	2	CD
cord-347298-7kqrl3rv	797	1	(	(	-LRB-
cord-347298-7kqrl3rv	797	2	PLA	PLA	NNP
cord-347298-7kqrl3rv	797	3	2	2	CD
cord-347298-7kqrl3rv	797	4	)	)	-RRB-
cord-347298-7kqrl3rv	797	5	on	on	IN
cord-347298-7kqrl3rv	797	6	arachidonyl	arachidonyl	NNP
cord-347298-7kqrl3rv	797	7	-	-	HYPH
cord-347298-7kqrl3rv	797	8	containing	contain	VBG
cord-347298-7kqrl3rv	797	9	phospholipids	phospholipid	NNS
cord-347298-7kqrl3rv	797	10	(	(	-LRB-
cord-347298-7kqrl3rv	797	11	usually	usually	RB
cord-347298-7kqrl3rv	797	12	a	a	DT
cord-347298-7kqrl3rv	797	13	1-acyl-2-arachidonylglycerophospholipid	1-acyl-2-arachidonylglycerophospholipid	CD
cord-347298-7kqrl3rv	797	14	)	)	-RRB-
cord-347298-7kqrl3rv	797	15	to	to	TO
cord-347298-7kqrl3rv	797	16	produce	produce	VB
cord-347298-7kqrl3rv	797	17	the	the	DT
cord-347298-7kqrl3rv	797	18	free	free	JJ
cord-347298-7kqrl3rv	797	19	fatty	fatty	JJ
cord-347298-7kqrl3rv	797	20	acid	acid	NN
cord-347298-7kqrl3rv	797	21	arachidonic	arachidonic	NN
cord-347298-7kqrl3rv	797	22	acid	acid	NN
cord-347298-7kqrl3rv	797	23	and	and	CC
cord-347298-7kqrl3rv	797	24	the	the	DT
cord-347298-7kqrl3rv	797	25	corresponding	correspond	VBG
cord-347298-7kqrl3rv	797	26	lysophospholipid	lysophospholipid	NN
cord-347298-7kqrl3rv	797	27	.	.	.
cord-347298-7kqrl3rv	798	1	Arachidonic	arachidonic	JJ
cord-347298-7kqrl3rv	798	2	acid	acid	NN
cord-347298-7kqrl3rv	798	3	is	be	VBZ
cord-347298-7kqrl3rv	798	4	converted	convert	VBN
cord-347298-7kqrl3rv	798	5	into	into	IN
cord-347298-7kqrl3rv	798	6	the	the	DT
cord-347298-7kqrl3rv	798	7	prostanoid	prostanoid	JJ
cord-347298-7kqrl3rv	798	8	precursor	precursor	NN
cord-347298-7kqrl3rv	798	9	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	798	10	H	h	NN
cord-347298-7kqrl3rv	798	11	2	2	CD
cord-347298-7kqrl3rv	799	1	(	(	-LRB-
cord-347298-7kqrl3rv	799	2	PGH	PGH	NNP
cord-347298-7kqrl3rv	799	3	2	2	CD
cord-347298-7kqrl3rv	799	4	)	)	-RRB-
cord-347298-7kqrl3rv	799	5	by	by	IN
cord-347298-7kqrl3rv	799	6	the	the	DT
cord-347298-7kqrl3rv	799	7	action	action	NN
cord-347298-7kqrl3rv	799	8	of	of	IN
cord-347298-7kqrl3rv	799	9	cyclooxygenases	cyclooxygenases	NNP
cord-347298-7kqrl3rv	800	1	and	and	CC
cord-347298-7kqrl3rv	800	2	this	this	DT
cord-347298-7kqrl3rv	800	3	is	be	VBZ
cord-347298-7kqrl3rv	800	4	further	further	RB
cord-347298-7kqrl3rv	800	5	converted	convert	VBN
cord-347298-7kqrl3rv	800	6	into	into	IN
cord-347298-7kqrl3rv	800	7	the	the	DT
cord-347298-7kqrl3rv	800	8	various	various	JJ
cord-347298-7kqrl3rv	800	9	prostanoid	prostanoid	JJ
cord-347298-7kqrl3rv	800	10	subtypes	subtype	NNS
cord-347298-7kqrl3rv	800	11	,	,	,
cord-347298-7kqrl3rv	800	12	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	800	13	(	(	-LRB-
cord-347298-7kqrl3rv	800	14	PGD	PGD	NNP
cord-347298-7kqrl3rv	800	15	,	,	,
cord-347298-7kqrl3rv	800	16	PGE	PGE	NNP
cord-347298-7kqrl3rv	800	17	,	,	,
cord-347298-7kqrl3rv	800	18	and	and	CC
cord-347298-7kqrl3rv	800	19	PGF	PGF	NNP
cord-347298-7kqrl3rv	800	20	)	)	-RRB-
cord-347298-7kqrl3rv	800	21	,	,	,
cord-347298-7kqrl3rv	800	22	prostacyclins	prostacyclins	NNP
cord-347298-7kqrl3rv	800	23	(	(	-LRB-
cord-347298-7kqrl3rv	800	24	PGI	PGI	NNP
cord-347298-7kqrl3rv	800	25	)	)	-RRB-
cord-347298-7kqrl3rv	800	26	,	,	,
cord-347298-7kqrl3rv	800	27	and	and	CC
cord-347298-7kqrl3rv	800	28	thromboxanes	thromboxanes	NNP
cord-347298-7kqrl3rv	800	29	(	(	-LRB-
cord-347298-7kqrl3rv	800	30	Tx	Tx	NNP
cord-347298-7kqrl3rv	800	31	)	)	-RRB-
cord-347298-7kqrl3rv	800	32	,	,	,
cord-347298-7kqrl3rv	800	33	by	by	IN
cord-347298-7kqrl3rv	800	34	the	the	DT
cord-347298-7kqrl3rv	800	35	action	action	NN
cord-347298-7kqrl3rv	800	36	of	of	IN
cord-347298-7kqrl3rv	800	37	specific	specific	JJ
cord-347298-7kqrl3rv	800	38	prostaglandin	prostaglandin	NN
cord-347298-7kqrl3rv	800	39	and	and	CC
cord-347298-7kqrl3rv	800	40	thromboxane	thromboxane	NN
cord-347298-7kqrl3rv	800	41	synthases	synthase	NNS
cord-347298-7kqrl3rv	800	42	.	.	.
cord-347298-7kqrl3rv	801	1	Synthesis	synthesis	NN
cord-347298-7kqrl3rv	801	2	of	of	IN
cord-347298-7kqrl3rv	801	3	lipoxins	lipoxin	NNS
cord-347298-7kqrl3rv	801	4	and	and	CC
cord-347298-7kqrl3rv	801	5	leukotrienes	leukotriene	NNS
cord-347298-7kqrl3rv	801	6	from	from	IN
cord-347298-7kqrl3rv	801	7	arachidonic	arachidonic	JJ
cord-347298-7kqrl3rv	801	8	acid	acid	NN
cord-347298-7kqrl3rv	801	9	occurs	occur	VBZ
cord-347298-7kqrl3rv	801	10	via	via	IN
cord-347298-7kqrl3rv	801	11	the	the	DT
cord-347298-7kqrl3rv	801	12	activity	activity	NN
cord-347298-7kqrl3rv	801	13	of	of	IN
cord-347298-7kqrl3rv	801	14	a	a	DT
cord-347298-7kqrl3rv	801	15	separate	separate	JJ
cord-347298-7kqrl3rv	801	16	lipoxygenase	lipoxygenase	NN
cord-347298-7kqrl3rv	801	17	enzyme	enzyme	NN
cord-347298-7kqrl3rv	801	18	(	(	-LRB-
cord-347298-7kqrl3rv	801	19	not	not	RB
cord-347298-7kqrl3rv	801	20	shown	show	VBN
cord-347298-7kqrl3rv	801	21	)	)	-RRB-
cord-347298-7kqrl3rv	801	22	.	.	.
cord-347298-7kqrl3rv	802	1	The	the	DT
cord-347298-7kqrl3rv	802	2	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	802	3	interact	interact	VBP
cord-347298-7kqrl3rv	802	4	with	with	IN
cord-347298-7kqrl3rv	802	5	their	-PRON-	PRP$
cord-347298-7kqrl3rv	802	6	various	various	JJ
cord-347298-7kqrl3rv	802	7	receptor	receptor	NN
cord-347298-7kqrl3rv	802	8	subtypes	subtype	NNS
cord-347298-7kqrl3rv	802	9	:	:	:
cord-347298-7kqrl3rv	802	10	there	there	EX
cord-347298-7kqrl3rv	802	11	are	be	VBP
cord-347298-7kqrl3rv	802	12	two	two	CD
cord-347298-7kqrl3rv	802	13	PGD	PGD	NNP
cord-347298-7kqrl3rv	802	14	receptors	receptor	NNS
cord-347298-7kqrl3rv	802	15	(	(	-LRB-
cord-347298-7kqrl3rv	802	16	DP1	DP1	NNP
cord-347298-7kqrl3rv	802	17	-	-	HYPH
cord-347298-7kqrl3rv	802	18	2	2	CD
cord-347298-7kqrl3rv	802	19	)	)	-RRB-
cord-347298-7kqrl3rv	802	20	and	and	CC
cord-347298-7kqrl3rv	802	21	four	four	CD
cord-347298-7kqrl3rv	802	22	PGE	PGE	NNP
cord-347298-7kqrl3rv	802	23	receptors	receptor	NNS
cord-347298-7kqrl3rv	802	24	(	(	-LRB-
cord-347298-7kqrl3rv	802	25	EP1	EP1	NNP
cord-347298-7kqrl3rv	802	26	-	-	HYPH
cord-347298-7kqrl3rv	802	27	4	4	CD
cord-347298-7kqrl3rv	802	28	)	)	-RRB-
cord-347298-7kqrl3rv	802	29	.	.	.
cord-347298-7kqrl3rv	803	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	803	2	is	be	VBZ
cord-347298-7kqrl3rv	803	3	the	the	DT
cord-347298-7kqrl3rv	803	4	cellular	cellular	JJ
cord-347298-7kqrl3rv	803	5	expression	expression	NN
cord-347298-7kqrl3rv	803	6	of	of	IN
cord-347298-7kqrl3rv	803	7	these	these	DT
cord-347298-7kqrl3rv	803	8	receptor	receptor	NN
cord-347298-7kqrl3rv	803	9	subtypes	subtype	NNS
cord-347298-7kqrl3rv	803	10	that	that	WDT
cord-347298-7kqrl3rv	803	11	ultimately	ultimately	RB
cord-347298-7kqrl3rv	803	12	determines	determine	VBZ
cord-347298-7kqrl3rv	803	13	the	the	DT
cord-347298-7kqrl3rv	803	14	eventual	eventual	JJ
cord-347298-7kqrl3rv	803	15	biological	biological	JJ
cord-347298-7kqrl3rv	803	16	responses	response	NNS
cord-347298-7kqrl3rv	803	17	;	;	:
cord-347298-7kqrl3rv	803	18	for	for	IN
cord-347298-7kqrl3rv	803	19	example	example	NN
cord-347298-7kqrl3rv	803	20	,	,	,
cord-347298-7kqrl3rv	803	21	different	different	JJ
cord-347298-7kqrl3rv	803	22	prostanoid	prostanoid	NN
cord-347298-7kqrl3rv	803	23	and	and	CC
cord-347298-7kqrl3rv	803	24	receptor	receptor	NN
cord-347298-7kqrl3rv	803	25	combinations	combination	NNS
cord-347298-7kqrl3rv	803	26	may	may	MD
cord-347298-7kqrl3rv	803	27	produce	produce	VB
cord-347298-7kqrl3rv	803	28	either	either	CC
cord-347298-7kqrl3rv	803	29	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	803	30	or	or	CC
cord-347298-7kqrl3rv	803	31	anti	anti	JJ
cord-347298-7kqrl3rv	803	32	-	-	JJ
cord-347298-7kqrl3rv	803	33	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	803	34	responses	response	NNS
cord-347298-7kqrl3rv	803	35	,	,	,
cord-347298-7kqrl3rv	803	36	or	or	CC
cord-347298-7kqrl3rv	803	37	may	may	MD
cord-347298-7kqrl3rv	803	38	have	have	VB
cord-347298-7kqrl3rv	803	39	opposing	oppose	VBG
cord-347298-7kqrl3rv	803	40	vasodilatory	vasodilatory	NN
cord-347298-7kqrl3rv	803	41	and	and	CC
cord-347298-7kqrl3rv	803	42	vasoconstrictive	vasoconstrictive	JJ
cord-347298-7kqrl3rv	803	43	effects	effect	NNS
cord-347298-7kqrl3rv	803	44	.	.	.
cord-347298-7kqrl3rv	804	1	When	when	WRB
cord-347298-7kqrl3rv	804	2	the	the	DT
cord-347298-7kqrl3rv	804	3	phospholipid	phospholipid	NN
cord-347298-7kqrl3rv	804	4	is	be	VBZ
cord-347298-7kqrl3rv	804	5	a	a	DT
cord-347298-7kqrl3rv	804	6	phosphatidylcholine	phosphatidylcholine	NN
cord-347298-7kqrl3rv	804	7	,	,	,
cord-347298-7kqrl3rv	804	8	a	a	DT
cord-347298-7kqrl3rv	804	9	lysophosphatidylcholine	lysophosphatidylcholine	NN
cord-347298-7kqrl3rv	804	10	(	(	-LRB-
cord-347298-7kqrl3rv	804	11	LPC	LPC	NNP
cord-347298-7kqrl3rv	804	12	)	)	-RRB-
cord-347298-7kqrl3rv	804	13	is	be	VBZ
cord-347298-7kqrl3rv	804	14	formed	form	VBN
cord-347298-7kqrl3rv	804	15	,	,	,
cord-347298-7kqrl3rv	804	16	which	which	WDT
cord-347298-7kqrl3rv	804	17	may	may	MD
cord-347298-7kqrl3rv	804	18	interact	interact	VB
cord-347298-7kqrl3rv	804	19	with	with	IN
cord-347298-7kqrl3rv	804	20	cells	cell	NNS
cord-347298-7kqrl3rv	804	21	via	via	IN
cord-347298-7kqrl3rv	804	22	G	g	NN
cord-347298-7kqrl3rv	804	23	-	-	HYPH
cord-347298-7kqrl3rv	804	24	protein	protein	NN
cord-347298-7kqrl3rv	804	25	-	-	HYPH
cord-347298-7kqrl3rv	804	26	coupled	couple	VBN
cord-347298-7kqrl3rv	804	27	receptor	receptor	NN
cord-347298-7kqrl3rv	804	28	-	-	HYPH
cord-347298-7kqrl3rv	804	29	mediated	mediate	VBN
cord-347298-7kqrl3rv	804	30	or	or	CC
cord-347298-7kqrl3rv	804	31	direct	direct	JJ
cord-347298-7kqrl3rv	804	32	membrane	membrane	NN
cord-347298-7kqrl3rv	804	33	interactions	interaction	NNS
cord-347298-7kqrl3rv	804	34	,	,	,
cord-347298-7kqrl3rv	804	35	or	or	CC
cord-347298-7kqrl3rv	804	36	may	may	MD
cord-347298-7kqrl3rv	804	37	undergo	undergo	VB
cord-347298-7kqrl3rv	804	38	further	further	JJ
cord-347298-7kqrl3rv	804	39	enzymatic	enzymatic	JJ
cord-347298-7kqrl3rv	804	40	modification	modification	NN
cord-347298-7kqrl3rv	804	41	to	to	TO
cord-347298-7kqrl3rv	804	42	form	form	VB
cord-347298-7kqrl3rv	804	43	other	other	JJ
cord-347298-7kqrl3rv	804	44	bioactive	bioactive	JJ
cord-347298-7kqrl3rv	804	45	lipids	lipid	NNS
cord-347298-7kqrl3rv	804	46	.	.	.
cord-347298-7kqrl3rv	805	1	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	805	2	and	and	CC
cord-347298-7kqrl3rv	805	3	inflammation	inflammation	NN
cord-347298-7kqrl3rv	805	4	in	in	IN
cord-347298-7kqrl3rv	805	5	the	the	DT
cord-347298-7kqrl3rv	805	6	testis	testis	NN
cord-347298-7kqrl3rv	805	7	(	(	-LRB-
cord-347298-7kqrl3rv	805	8	Ishikawa	Ishikawa	NNP
cord-347298-7kqrl3rv	805	9	and	and	CC
cord-347298-7kqrl3rv	805	10	Morris	Morris	NNP
cord-347298-7kqrl3rv	805	11	2006	2006	CD
cord-347298-7kqrl3rv	805	12	;	;	:
cord-347298-7kqrl3rv	805	13	Ishikawa	Ishikawa	NNP
cord-347298-7kqrl3rv	805	14	et	et	NNP
cord-347298-7kqrl3rv	805	15	al	al	NNP
cord-347298-7kqrl3rv	805	16	.	.	NNP
cord-347298-7kqrl3rv	805	17	2005	2005	CD
cord-347298-7kqrl3rv	805	18	)	)	-RRB-
cord-347298-7kqrl3rv	805	19	.	.	.
cord-347298-7kqrl3rv	806	1	In	in	IN
cord-347298-7kqrl3rv	806	2	addition	addition	NN
cord-347298-7kqrl3rv	806	3	,	,	,
cord-347298-7kqrl3rv	806	4	PGE	PGE	NNP
cord-347298-7kqrl3rv	806	5	2	2	CD
cord-347298-7kqrl3rv	806	6	and	and	CC
cord-347298-7kqrl3rv	806	7	PGF	PGF	NNP
cord-347298-7kqrl3rv	806	8	2	2	CD
cord-347298-7kqrl3rv	806	9	produced	produce	VBN
cord-347298-7kqrl3rv	806	10	by	by	IN
cord-347298-7kqrl3rv	806	11	mature	mature	JJ
cord-347298-7kqrl3rv	806	12	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	806	13	play	play	VB
cord-347298-7kqrl3rv	806	14	a	a	DT
cord-347298-7kqrl3rv	806	15	role	role	NN
cord-347298-7kqrl3rv	806	16	in	in	IN
cord-347298-7kqrl3rv	806	17	the	the	DT
cord-347298-7kqrl3rv	806	18	acrosome	acrosome	NNP
cord-347298-7kqrl3rv	806	19	reaction	reaction	NN
cord-347298-7kqrl3rv	807	1	(	(	-LRB-
cord-347298-7kqrl3rv	807	2	Breitbart	Breitbart	NNP
cord-347298-7kqrl3rv	807	3	et	et	NNP
cord-347298-7kqrl3rv	807	4	al	al	NNP
cord-347298-7kqrl3rv	807	5	.	.	.
cord-347298-7kqrl3rv	808	1	1995	1995	CD
cord-347298-7kqrl3rv	808	2	;	;	:
cord-347298-7kqrl3rv	808	3	Joyce	Joyce	NNP
cord-347298-7kqrl3rv	808	4	et	et	NNP
cord-347298-7kqrl3rv	808	5	al	al	NNP
cord-347298-7kqrl3rv	808	6	.	.	NNP
cord-347298-7kqrl3rv	808	7	1987	1987	CD
cord-347298-7kqrl3rv	808	8	)	)	-RRB-
cord-347298-7kqrl3rv	808	9	.	.	.
cord-347298-7kqrl3rv	809	1	Products	product	NNS
cord-347298-7kqrl3rv	809	2	of	of	IN
cord-347298-7kqrl3rv	809	3	the	the	DT
cord-347298-7kqrl3rv	809	4	lipoxygenase	lipoxygenase	NNP
cord-347298-7kqrl3rv	809	5	pathway	pathway	NN
cord-347298-7kqrl3rv	809	6	,	,	,
cord-347298-7kqrl3rv	809	7	such	such	JJ
cord-347298-7kqrl3rv	809	8	as	as	IN
cord-347298-7kqrl3rv	809	9	leukotriene	leukotriene	NN
cord-347298-7kqrl3rv	809	10	B	B	NNP
cord-347298-7kqrl3rv	809	11	4	4	CD
cord-347298-7kqrl3rv	809	12	,	,	,
cord-347298-7kqrl3rv	809	13	are	be	VBP
cord-347298-7kqrl3rv	809	14	also	also	RB
cord-347298-7kqrl3rv	809	15	produced	produce	VBN
cord-347298-7kqrl3rv	809	16	by	by	IN
cord-347298-7kqrl3rv	809	17	the	the	DT
cord-347298-7kqrl3rv	809	18	testis	testis	NN
cord-347298-7kqrl3rv	809	19	,	,	,
cord-347298-7kqrl3rv	809	20	where	where	WRB
cord-347298-7kqrl3rv	809	21	they	-PRON-	PRP
cord-347298-7kqrl3rv	809	22	intervene	intervene	VBP
cord-347298-7kqrl3rv	809	23	in	in	IN
cord-347298-7kqrl3rv	809	24	the	the	DT
cord-347298-7kqrl3rv	809	25	regulation	regulation	NN
cord-347298-7kqrl3rv	809	26	of	of	IN
cord-347298-7kqrl3rv	809	27	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	809	28	cell	cell	NN
cord-347298-7kqrl3rv	809	29	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	809	30	by	by	IN
cord-347298-7kqrl3rv	809	31	LH	LH	NNP
cord-347298-7kqrl3rv	809	32	(	(	-LRB-
cord-347298-7kqrl3rv	809	33	Papadopoulos	Papadopoulos	NNP
cord-347298-7kqrl3rv	809	34	et	et	NNP
cord-347298-7kqrl3rv	809	35	al	al	NNP
cord-347298-7kqrl3rv	809	36	.	.	NNP
cord-347298-7kqrl3rv	809	37	1987	1987	CD
cord-347298-7kqrl3rv	809	38	;	;	:
cord-347298-7kqrl3rv	809	39	Sullivan	Sullivan	NNP
cord-347298-7kqrl3rv	809	40	and	and	CC
cord-347298-7kqrl3rv	809	41	Cooke	Cooke	NNP
cord-347298-7kqrl3rv	809	42	1985	1985	CD
cord-347298-7kqrl3rv	809	43	)	)	-RRB-
cord-347298-7kqrl3rv	809	44	,	,	,
cord-347298-7kqrl3rv	809	45	but	but	CC
cord-347298-7kqrl3rv	809	46	other	other	JJ
cord-347298-7kqrl3rv	809	47	functions	function	NNS
cord-347298-7kqrl3rv	809	48	can	can	MD
cord-347298-7kqrl3rv	809	49	be	be	VB
cord-347298-7kqrl3rv	809	50	expected	expect	VBN
cord-347298-7kqrl3rv	809	51	.	.	.
cord-347298-7kqrl3rv	810	1	Direct	direct	JJ
cord-347298-7kqrl3rv	810	2	evidence	evidence	NN
cord-347298-7kqrl3rv	810	3	for	for	IN
cord-347298-7kqrl3rv	810	4	the	the	DT
cord-347298-7kqrl3rv	810	5	anticipated	anticipate	VBN
cord-347298-7kqrl3rv	810	6	roles	role	NNS
cord-347298-7kqrl3rv	810	7	of	of	IN
cord-347298-7kqrl3rv	810	8	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	810	9	or	or	CC
cord-347298-7kqrl3rv	810	10	lipoxygenase	lipoxygenase	NN
cord-347298-7kqrl3rv	810	11	products	product	NNS
cord-347298-7kqrl3rv	810	12	in	in	IN
cord-347298-7kqrl3rv	810	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	810	14	inflammation	inflammation	NN
cord-347298-7kqrl3rv	810	15	and	and	CC
cord-347298-7kqrl3rv	810	16	immunity	immunity	NN
cord-347298-7kqrl3rv	810	17	is	be	VBZ
cord-347298-7kqrl3rv	810	18	lacking	lack	VBG
cord-347298-7kqrl3rv	810	19	.	.	.
cord-347298-7kqrl3rv	811	1	Initially	initially	RB
cord-347298-7kqrl3rv	811	2	,	,	,
cord-347298-7kqrl3rv	811	3	there	there	EX
cord-347298-7kqrl3rv	811	4	was	be	VBD
cord-347298-7kqrl3rv	811	5	some	some	DT
cord-347298-7kqrl3rv	811	6	evidence	evidence	NN
cord-347298-7kqrl3rv	811	7	to	to	TO
cord-347298-7kqrl3rv	811	8	suggest	suggest	VB
cord-347298-7kqrl3rv	811	9	that	that	IN
cord-347298-7kqrl3rv	811	10	PGE	PGE	NNP
cord-347298-7kqrl3rv	811	11	2	2	CD
cord-347298-7kqrl3rv	811	12	might	may	MD
cord-347298-7kqrl3rv	811	13	be	be	VB
cord-347298-7kqrl3rv	811	14	responsible	responsible	JJ
cord-347298-7kqrl3rv	811	15	for	for	IN
cord-347298-7kqrl3rv	811	16	the	the	DT
cord-347298-7kqrl3rv	811	17	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	811	18	phenotype	phenotype	NN
cord-347298-7kqrl3rv	811	19	of	of	IN
cord-347298-7kqrl3rv	811	20	resident	resident	JJ
cord-347298-7kqrl3rv	811	21	testicular	testicular	JJ
cord-347298-7kqrl3rv	811	22	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	811	23	.	.	.
cord-347298-7kqrl3rv	812	1	This	this	DT
cord-347298-7kqrl3rv	812	2	now	now	RB
cord-347298-7kqrl3rv	812	3	seems	seem	VBZ
cord-347298-7kqrl3rv	812	4	unlikely	unlikely	JJ
cord-347298-7kqrl3rv	812	5	,	,	,
cord-347298-7kqrl3rv	812	6	because	because	IN
cord-347298-7kqrl3rv	812	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	812	8	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	812	9	produce	produce	VBP
cord-347298-7kqrl3rv	812	10	little	little	JJ
cord-347298-7kqrl3rv	812	11	PGE	PGE	NNP
cord-347298-7kqrl3rv	812	12	2	2	CD
cord-347298-7kqrl3rv	812	13	under	under	IN
cord-347298-7kqrl3rv	812	14	normal	normal	JJ
cord-347298-7kqrl3rv	812	15	conditions	condition	NNS
cord-347298-7kqrl3rv	812	16	,	,	,
cord-347298-7kqrl3rv	812	17	and	and	CC
cord-347298-7kqrl3rv	812	18	blocking	block	VBG
cord-347298-7kqrl3rv	812	19	COX2	cox2	JJ
cord-347298-7kqrl3rv	812	20	activity	activity	NN
cord-347298-7kqrl3rv	812	21	in	in	IN
cord-347298-7kqrl3rv	812	22	vivo	vivo	NN
cord-347298-7kqrl3rv	812	23	or	or	CC
cord-347298-7kqrl3rv	812	24	in	in	IN
cord-347298-7kqrl3rv	812	25	vitro	vitro	FW
cord-347298-7kqrl3rv	812	26	does	do	VBZ
cord-347298-7kqrl3rv	812	27	not	not	RB
cord-347298-7kqrl3rv	812	28	affect	affect	VB
cord-347298-7kqrl3rv	812	29	the	the	DT
cord-347298-7kqrl3rv	812	30	production	production	NN
cord-347298-7kqrl3rv	812	31	of	of	IN
cord-347298-7kqrl3rv	812	32	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	812	33	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	812	34	in	in	IN
cord-347298-7kqrl3rv	812	35	the	the	DT
cord-347298-7kqrl3rv	812	36	testis	testis	NN
cord-347298-7kqrl3rv	812	37	in	in	IN
cord-347298-7kqrl3rv	812	38	response	response	NN
cord-347298-7kqrl3rv	812	39	to	to	IN
cord-347298-7kqrl3rv	812	40	LPS	LPS	NNP
cord-347298-7kqrl3rv	812	41	(	(	-LRB-
cord-347298-7kqrl3rv	812	42	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	812	43	et	et	NNP
cord-347298-7kqrl3rv	812	44	al	al	NNP
cord-347298-7kqrl3rv	812	45	.	.	NNP
cord-347298-7kqrl3rv	812	46	2002a	2002a	CD
cord-347298-7kqrl3rv	812	47	;	;	:
cord-347298-7kqrl3rv	812	48	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	812	49	et	et	NNP
cord-347298-7kqrl3rv	812	50	al	al	NNP
cord-347298-7kqrl3rv	812	51	.	.	.
cord-347298-7kqrl3rv	813	1	2007	2007	CD
cord-347298-7kqrl3rv	814	1	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	814	2	et	et	NNP
cord-347298-7kqrl3rv	814	3	al	al	NNP
cord-347298-7kqrl3rv	814	4	.	.	NNP
cord-347298-7kqrl3rv	814	5	,	,	,
cord-347298-7kqrl3rv	814	6	2008	2008	CD
cord-347298-7kqrl3rv	814	7	.	.	.
cord-347298-7kqrl3rv	815	1	In	in	IN
cord-347298-7kqrl3rv	815	2	the	the	DT
cord-347298-7kqrl3rv	815	3	rat	rat	NN
cord-347298-7kqrl3rv	815	4	,	,	,
cord-347298-7kqrl3rv	815	5	chronic	chronic	JJ
cord-347298-7kqrl3rv	815	6	inhibition	inhibition	NN
cord-347298-7kqrl3rv	815	7	of	of	IN
cord-347298-7kqrl3rv	815	8	COX2	cox2	JJ
cord-347298-7kqrl3rv	815	9	inhibited	inhibit	VBN
cord-347298-7kqrl3rv	815	10	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	815	11	fluid	fluid	JJ
cord-347298-7kqrl3rv	815	12	formation	formation	NN
cord-347298-7kqrl3rv	815	13	in	in	IN
cord-347298-7kqrl3rv	815	14	normal	normal	JJ
cord-347298-7kqrl3rv	815	15	testes	testis	NNS
cord-347298-7kqrl3rv	815	16	,	,	,
cord-347298-7kqrl3rv	815	17	but	but	CC
cord-347298-7kqrl3rv	815	18	ameliorated	ameliorate	VBD
cord-347298-7kqrl3rv	815	19	the	the	DT
cord-347298-7kqrl3rv	815	20	loss	loss	NN
cord-347298-7kqrl3rv	815	21	of	of	IN
cord-347298-7kqrl3rv	815	22	fluid	fluid	NN
cord-347298-7kqrl3rv	815	23	that	that	WDT
cord-347298-7kqrl3rv	815	24	usually	usually	RB
cord-347298-7kqrl3rv	815	25	occurs	occur	VBZ
cord-347298-7kqrl3rv	815	26	during	during	IN
cord-347298-7kqrl3rv	815	27	LPS	LPS	NNP
cord-347298-7kqrl3rv	815	28	-	-	HYPH
cord-347298-7kqrl3rv	815	29	induced	induce	VBN
cord-347298-7kqrl3rv	815	30	inflammation	inflammation	NN
cord-347298-7kqrl3rv	816	1	(	(	-LRB-
cord-347298-7kqrl3rv	816	2	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	816	3	et	et	NNP
cord-347298-7kqrl3rv	816	4	al	al	NNP
cord-347298-7kqrl3rv	816	5	.	.	NNP
cord-347298-7kqrl3rv	816	6	2008	2008	CD
cord-347298-7kqrl3rv	816	7	)	)	-RRB-
cord-347298-7kqrl3rv	816	8	.	.	.
cord-347298-7kqrl3rv	817	1	The	the	DT
cord-347298-7kqrl3rv	817	2	latter	latter	JJ
cord-347298-7kqrl3rv	817	3	data	datum	NNS
cord-347298-7kqrl3rv	817	4	would	would	MD
cord-347298-7kqrl3rv	817	5	seem	seem	VB
cord-347298-7kqrl3rv	817	6	to	to	TO
cord-347298-7kqrl3rv	817	7	indicate	indicate	VB
cord-347298-7kqrl3rv	817	8	roles	role	NNS
cord-347298-7kqrl3rv	817	9	for	for	IN
cord-347298-7kqrl3rv	817	10	products	product	NNS
cord-347298-7kqrl3rv	817	11	of	of	IN
cord-347298-7kqrl3rv	817	12	COX2	COX2	NNP
cord-347298-7kqrl3rv	817	13	in	in	IN
cord-347298-7kqrl3rv	817	14	the	the	DT
cord-347298-7kqrl3rv	817	15	control	control	NN
cord-347298-7kqrl3rv	817	16	of	of	IN
cord-347298-7kqrl3rv	817	17	vascular	vascular	JJ
cord-347298-7kqrl3rv	817	18	tone	tone	NN
cord-347298-7kqrl3rv	817	19	in	in	IN
cord-347298-7kqrl3rv	817	20	the	the	DT
cord-347298-7kqrl3rv	817	21	normal	normal	JJ
cord-347298-7kqrl3rv	817	22	and	and	CC
cord-347298-7kqrl3rv	817	23	inflamed	inflamed	JJ
cord-347298-7kqrl3rv	817	24	testis	testis	NN
cord-347298-7kqrl3rv	817	25	and	and	CC
cord-347298-7kqrl3rv	817	26	this	this	DT
cord-347298-7kqrl3rv	817	27	deserves	deserve	VBZ
cord-347298-7kqrl3rv	817	28	further	further	JJ
cord-347298-7kqrl3rv	817	29	exploration	exploration	NN
cord-347298-7kqrl3rv	817	30	.	.	.
cord-347298-7kqrl3rv	818	1	When	when	WRB
cord-347298-7kqrl3rv	818	2	phosphocholine	phosphocholine	FW
cord-347298-7kqrl3rv	818	3	(	(	-LRB-
cord-347298-7kqrl3rv	818	4	PC)-containing	pc)-containe	VBG
cord-347298-7kqrl3rv	818	5	phospholipids	phospholipid	NNS
cord-347298-7kqrl3rv	818	6	are	be	VBP
cord-347298-7kqrl3rv	818	7	used	use	VBN
cord-347298-7kqrl3rv	818	8	as	as	IN
cord-347298-7kqrl3rv	818	9	the	the	DT
cord-347298-7kqrl3rv	818	10	substrate	substrate	NN
cord-347298-7kqrl3rv	818	11	for	for	IN
cord-347298-7kqrl3rv	818	12	PLA	PLA	NNP
cord-347298-7kqrl3rv	818	13	2	2	CD
cord-347298-7kqrl3rv	818	14	action	action	NN
cord-347298-7kqrl3rv	818	15	,	,	,
cord-347298-7kqrl3rv	818	16	lysophosphatidylcholines	lysophosphatidylcholine	NNS
cord-347298-7kqrl3rv	818	17	(	(	-LRB-
cord-347298-7kqrl3rv	818	18	LPCs	LPCs	NNP
cord-347298-7kqrl3rv	818	19	)	)	-RRB-
cord-347298-7kqrl3rv	818	20	are	be	VBP
cord-347298-7kqrl3rv	818	21	also	also	RB
cord-347298-7kqrl3rv	818	22	produced	produce	VBN
cord-347298-7kqrl3rv	818	23	(	(	-LRB-
cord-347298-7kqrl3rv	818	24	Aoki	Aoki	NNP
cord-347298-7kqrl3rv	818	25	et	et	NNP
cord-347298-7kqrl3rv	818	26	al	al	NNP
cord-347298-7kqrl3rv	818	27	.	.	.
cord-347298-7kqrl3rv	818	28	2002	2002	CD
cord-347298-7kqrl3rv	818	29	;	;	:
cord-347298-7kqrl3rv	818	30	Snyder	Snyder	NNP
cord-347298-7kqrl3rv	818	31	1990	1990	CD
cord-347298-7kqrl3rv	818	32	)	)	-RRB-
cord-347298-7kqrl3rv	818	33	.	.	.
cord-347298-7kqrl3rv	819	1	LPCs	lpc	NNS
cord-347298-7kqrl3rv	819	2	usually	usually	RB
cord-347298-7kqrl3rv	819	3	comprise	comprise	VBP
cord-347298-7kqrl3rv	819	4	a	a	DT
cord-347298-7kqrl3rv	819	5	glycerophosphocholine	glycerophosphocholine	NN
cord-347298-7kqrl3rv	819	6	backbone	backbone	NN
cord-347298-7kqrl3rv	819	7	,	,	,
cord-347298-7kqrl3rv	819	8	a	a	DT
cord-347298-7kqrl3rv	819	9	single	single	JJ
cord-347298-7kqrl3rv	819	10	long	long	JJ
cord-347298-7kqrl3rv	819	11	-	-	HYPH
cord-347298-7kqrl3rv	819	12	chain	chain	NN
cord-347298-7kqrl3rv	819	13	fatty	fatty	JJ
cord-347298-7kqrl3rv	819	14	acid	acid	NN
cord-347298-7kqrl3rv	819	15	,	,	,
cord-347298-7kqrl3rv	819	16	and	and	CC
cord-347298-7kqrl3rv	819	17	a	a	DT
cord-347298-7kqrl3rv	819	18	free	free	JJ
cord-347298-7kqrl3rv	819	19	hydroxyl	hydroxyl	NN
cord-347298-7kqrl3rv	819	20	group	group	NN
cord-347298-7kqrl3rv	819	21	(	(	-LRB-
cord-347298-7kqrl3rv	819	22	Khaselev	Khaselev	NNP
cord-347298-7kqrl3rv	819	23	and	and	CC
cord-347298-7kqrl3rv	819	24	Murphy	Murphy	NNP
cord-347298-7kqrl3rv	819	25	2000	2000	CD
cord-347298-7kqrl3rv	819	26	)	)	-RRB-
cord-347298-7kqrl3rv	819	27	.	.	.
cord-347298-7kqrl3rv	820	1	The	the	DT
cord-347298-7kqrl3rv	820	2	platelet	platelet	NN
cord-347298-7kqrl3rv	820	3	-	-	HYPH
cord-347298-7kqrl3rv	820	4	activating	activate	VBG
cord-347298-7kqrl3rv	820	5	factors	factor	NNS
cord-347298-7kqrl3rv	820	6	(	(	-LRB-
cord-347298-7kqrl3rv	820	7	PAFs	PAFs	NNP
cord-347298-7kqrl3rv	820	8	)	)	-RRB-
cord-347298-7kqrl3rv	820	9	are	be	VBP
cord-347298-7kqrl3rv	820	10	a	a	DT
cord-347298-7kqrl3rv	820	11	subset	subset	NN
cord-347298-7kqrl3rv	820	12	of	of	IN
cord-347298-7kqrl3rv	820	13	LPCs	lpc	NNS
cord-347298-7kqrl3rv	820	14	with	with	IN
cord-347298-7kqrl3rv	820	15	an	an	DT
cord-347298-7kqrl3rv	820	16	acetyl	acetyl	NN
cord-347298-7kqrl3rv	820	17	group	group	NN
cord-347298-7kqrl3rv	820	18	in	in	IN
cord-347298-7kqrl3rv	820	19	place	place	NN
cord-347298-7kqrl3rv	820	20	of	of	IN
cord-347298-7kqrl3rv	820	21	the	the	DT
cord-347298-7kqrl3rv	820	22	hydroxyl	hydroxyl	NN
cord-347298-7kqrl3rv	820	23	group	group	NN
cord-347298-7kqrl3rv	820	24	,	,	,
cord-347298-7kqrl3rv	820	25	which	which	WDT
cord-347298-7kqrl3rv	820	26	facilitates	facilitate	VBZ
cord-347298-7kqrl3rv	820	27	binding	binding	NN
cord-347298-7kqrl3rv	820	28	to	to	IN
cord-347298-7kqrl3rv	820	29	the	the	DT
cord-347298-7kqrl3rv	820	30	PAF	PAF	NNP
cord-347298-7kqrl3rv	820	31	receptor	receptor	NN
cord-347298-7kqrl3rv	820	32	(	(	-LRB-
cord-347298-7kqrl3rv	820	33	Snyder	Snyder	NNP
cord-347298-7kqrl3rv	820	34	1990	1990	CD
cord-347298-7kqrl3rv	820	35	)	)	-RRB-
cord-347298-7kqrl3rv	820	36	.	.	.
cord-347298-7kqrl3rv	821	1	The	the	DT
cord-347298-7kqrl3rv	821	2	effective	effective	JJ
cord-347298-7kqrl3rv	821	3	concentrations	concentration	NNS
cord-347298-7kqrl3rv	821	4	of	of	IN
cord-347298-7kqrl3rv	821	5	these	these	DT
cord-347298-7kqrl3rv	821	6	phospholipidderived	phospholipidderived	JJ
cord-347298-7kqrl3rv	821	7	molecules	molecule	NNS
cord-347298-7kqrl3rv	821	8	in	in	IN
cord-347298-7kqrl3rv	821	9	biological	biological	JJ
cord-347298-7kqrl3rv	821	10	fluids	fluid	NNS
cord-347298-7kqrl3rv	821	11	are	be	VBP
cord-347298-7kqrl3rv	821	12	normally	normally	RB
cord-347298-7kqrl3rv	821	13	tightly	tightly	RB
cord-347298-7kqrl3rv	821	14	controlled	control	VBN
cord-347298-7kqrl3rv	821	15	by	by	IN
cord-347298-7kqrl3rv	821	16	binding	bind	VBG
cord-347298-7kqrl3rv	821	17	to	to	IN
cord-347298-7kqrl3rv	821	18	albumin	albumin	NN
cord-347298-7kqrl3rv	821	19	and	and	CC
cord-347298-7kqrl3rv	821	20	lipoproteins	lipoprotein	NNS
cord-347298-7kqrl3rv	822	1	(	(	-LRB-
cord-347298-7kqrl3rv	822	2	Croset	Croset	NNP
cord-347298-7kqrl3rv	822	3	et	et	NNP
cord-347298-7kqrl3rv	822	4	al	al	NNP
cord-347298-7kqrl3rv	822	5	.	.	.
cord-347298-7kqrl3rv	822	6	2000	2000	CD
cord-347298-7kqrl3rv	822	7	)	)	-RRB-
cord-347298-7kqrl3rv	822	8	,	,	,
cord-347298-7kqrl3rv	822	9	since	since	IN
cord-347298-7kqrl3rv	822	10	some	some	DT
cord-347298-7kqrl3rv	822	11	LPCs	lpc	NNS
cord-347298-7kqrl3rv	822	12	,	,	,
cord-347298-7kqrl3rv	822	13	particularly	particularly	RB
cord-347298-7kqrl3rv	822	14	those	those	DT
cord-347298-7kqrl3rv	822	15	derived	derive	VBN
cord-347298-7kqrl3rv	822	16	from	from	IN
cord-347298-7kqrl3rv	822	17	the	the	DT
cord-347298-7kqrl3rv	822	18	saturated	saturate	VBN
cord-347298-7kqrl3rv	822	19	C16	C16	NNP
cord-347298-7kqrl3rv	822	20	and	and	CC
cord-347298-7kqrl3rv	822	21	C18	C18	NNP
cord-347298-7kqrl3rv	822	22	fatty	fatty	JJ
cord-347298-7kqrl3rv	822	23	acids	acid	NNS
cord-347298-7kqrl3rv	822	24	,	,	,
cord-347298-7kqrl3rv	822	25	cause	cause	VB
cord-347298-7kqrl3rv	822	26	cell	cell	NN
cord-347298-7kqrl3rv	822	27	lysis	lysis	NN
cord-347298-7kqrl3rv	822	28	at	at	IN
cord-347298-7kqrl3rv	822	29	high	high	JJ
cord-347298-7kqrl3rv	822	30	concentrations	concentration	NNS
cord-347298-7kqrl3rv	822	31	(	(	-LRB-
cord-347298-7kqrl3rv	822	32	Weltzien	Weltzien	NNP
cord-347298-7kqrl3rv	822	33	1979	1979	CD
cord-347298-7kqrl3rv	822	34	)	)	-RRB-
cord-347298-7kqrl3rv	822	35	.	.	.
cord-347298-7kqrl3rv	823	1	At	at	IN
cord-347298-7kqrl3rv	823	2	physiological	physiological	JJ
cord-347298-7kqrl3rv	823	3	concentrations	concentration	NNS
cord-347298-7kqrl3rv	823	4	,	,	,
cord-347298-7kqrl3rv	823	5	however	however	RB
cord-347298-7kqrl3rv	823	6	,	,	,
cord-347298-7kqrl3rv	823	7	LPCs	lpc	NNS
cord-347298-7kqrl3rv	823	8	induce	induce	VBP
cord-347298-7kqrl3rv	823	9	specific	specific	JJ
cord-347298-7kqrl3rv	823	10	responses	response	NNS
cord-347298-7kqrl3rv	823	11	in	in	IN
cord-347298-7kqrl3rv	823	12	various	various	JJ
cord-347298-7kqrl3rv	823	13	cell	cell	NN
cord-347298-7kqrl3rv	823	14	types	type	NNS
cord-347298-7kqrl3rv	823	15	,	,	,
cord-347298-7kqrl3rv	823	16	including	include	VBG
cord-347298-7kqrl3rv	823	17	most	most	JJS
cord-347298-7kqrl3rv	823	18	immune	immune	JJ
cord-347298-7kqrl3rv	823	19	cell	cell	NN
cord-347298-7kqrl3rv	823	20	types	type	NNS
cord-347298-7kqrl3rv	823	21	.	.	.
cord-347298-7kqrl3rv	824	1	Nonacetylated	nonacetylated	JJ
cord-347298-7kqrl3rv	824	2	LPCs	lpc	NNS
cord-347298-7kqrl3rv	824	3	are	be	VBP
cord-347298-7kqrl3rv	824	4	chemotactic	chemotactic	VBN
cord-347298-7kqrl3rv	824	5	toward	toward	IN
cord-347298-7kqrl3rv	824	6	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	824	7	,	,	,
cord-347298-7kqrl3rv	824	8	T	t	NN
cord-347298-7kqrl3rv	824	9	cells	cell	NNS
cord-347298-7kqrl3rv	824	10	,	,	,
cord-347298-7kqrl3rv	824	11	and	and	CC
cord-347298-7kqrl3rv	824	12	NK	NK	NNP
cord-347298-7kqrl3rv	824	13	cells	cell	NNS
cord-347298-7kqrl3rv	824	14	,	,	,
cord-347298-7kqrl3rv	824	15	and	and	CC
cord-347298-7kqrl3rv	824	16	stimulate	stimulate	VB
cord-347298-7kqrl3rv	824	17	COX2	cox2	JJ
cord-347298-7kqrl3rv	824	18	expression	expression	NN
cord-347298-7kqrl3rv	824	19	by	by	IN
cord-347298-7kqrl3rv	824	20	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	824	21	,	,	,
cord-347298-7kqrl3rv	824	22	cytokine	cytokine	JJ
cord-347298-7kqrl3rv	824	23	production	production	NN
cord-347298-7kqrl3rv	824	24	by	by	IN
cord-347298-7kqrl3rv	824	25	T	t	NN
cord-347298-7kqrl3rv	824	26	cells	cell	NNS
cord-347298-7kqrl3rv	824	27	,	,	,
cord-347298-7kqrl3rv	824	28	and	and	CC
cord-347298-7kqrl3rv	824	29	the	the	DT
cord-347298-7kqrl3rv	824	30	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	824	31	activity	activity	NN
cord-347298-7kqrl3rv	824	32	of	of	IN
cord-347298-7kqrl3rv	824	33	NK	NK	NNP
cord-347298-7kqrl3rv	824	34	cells	cell	NNS
cord-347298-7kqrl3rv	824	35	(	(	-LRB-
cord-347298-7kqrl3rv	824	36	Légrádi	Légrádi	NNP
cord-347298-7kqrl3rv	824	37	et	et	FW
cord-347298-7kqrl3rv	824	38	al	al	NNP
cord-347298-7kqrl3rv	824	39	.	.	.
cord-347298-7kqrl3rv	825	1	2004	2004	CD
cord-347298-7kqrl3rv	825	2	;	;	:
cord-347298-7kqrl3rv	825	3	Radu	Radu	NNP
cord-347298-7kqrl3rv	825	4	et	et	NNP
cord-347298-7kqrl3rv	825	5	al	al	NNP
cord-347298-7kqrl3rv	825	6	.	.	.
cord-347298-7kqrl3rv	826	1	2004	2004	CD
cord-347298-7kqrl3rv	826	2	;	;	:
cord-347298-7kqrl3rv	826	3	Whalen	Whalen	NNP
cord-347298-7kqrl3rv	826	4	et	et	NNP
cord-347298-7kqrl3rv	826	5	al	al	NNP
cord-347298-7kqrl3rv	826	6	.	.	.
cord-347298-7kqrl3rv	827	1	1999	1999	CD
cord-347298-7kqrl3rv	827	2	;	;	:
cord-347298-7kqrl3rv	827	3	Yang	Yang	NNP
cord-347298-7kqrl3rv	827	4	et	et	NNP
cord-347298-7kqrl3rv	827	5	al	al	NNP
cord-347298-7kqrl3rv	827	6	.	.	NNP
cord-347298-7kqrl3rv	827	7	2005	2005	CD
cord-347298-7kqrl3rv	827	8	)	)	-RRB-
cord-347298-7kqrl3rv	827	9	.	.	.
cord-347298-7kqrl3rv	828	1	In	in	IN
cord-347298-7kqrl3rv	828	2	addition	addition	NN
cord-347298-7kqrl3rv	828	3	,	,	,
cord-347298-7kqrl3rv	828	4	LPCs	lpc	NNS
cord-347298-7kqrl3rv	828	5	induce	induce	VBP
cord-347298-7kqrl3rv	828	6	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	828	7	in	in	IN
cord-347298-7kqrl3rv	828	8	T	t	NN
cord-347298-7kqrl3rv	828	9	cells	cell	NNS
cord-347298-7kqrl3rv	828	10	,	,	,
cord-347298-7kqrl3rv	828	11	indicating	indicate	VBG
cord-347298-7kqrl3rv	828	12	a	a	DT
cord-347298-7kqrl3rv	828	13	role	role	NN
cord-347298-7kqrl3rv	828	14	in	in	IN
cord-347298-7kqrl3rv	828	15	immunosuppression	immunosuppression	NN
cord-347298-7kqrl3rv	828	16	as	as	RB
cord-347298-7kqrl3rv	828	17	well	well	RB
cord-347298-7kqrl3rv	829	1	(	(	-LRB-
cord-347298-7kqrl3rv	829	2	Kabarowski	Kabarowski	NNP
cord-347298-7kqrl3rv	829	3	et	et	NNP
cord-347298-7kqrl3rv	829	4	al	al	NNP
cord-347298-7kqrl3rv	829	5	.	.	.
cord-347298-7kqrl3rv	830	1	2002	2002	CD
cord-347298-7kqrl3rv	830	2	;	;	:
cord-347298-7kqrl3rv	830	3	Takeda	Takeda	NNP
cord-347298-7kqrl3rv	830	4	et	et	NNP
cord-347298-7kqrl3rv	830	5	al	al	NNP
cord-347298-7kqrl3rv	830	6	.	.	.
cord-347298-7kqrl3rv	830	7	1982	1982	CD
cord-347298-7kqrl3rv	830	8	)	)	-RRB-
cord-347298-7kqrl3rv	830	9	.	.	.
cord-347298-7kqrl3rv	831	1	The	the	DT
cord-347298-7kqrl3rv	831	2	details	detail	NNS
cord-347298-7kqrl3rv	831	3	of	of	IN
cord-347298-7kqrl3rv	831	4	the	the	DT
cord-347298-7kqrl3rv	831	5	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	831	6	involved	involve	VBN
cord-347298-7kqrl3rv	831	7	are	be	VBP
cord-347298-7kqrl3rv	831	8	poorly	poorly	RB
cord-347298-7kqrl3rv	831	9	understood	understand	VBN
cord-347298-7kqrl3rv	831	10	.	.	.
cord-347298-7kqrl3rv	832	1	While	while	IN
cord-347298-7kqrl3rv	832	2	there	there	EX
cord-347298-7kqrl3rv	832	3	is	be	VBZ
cord-347298-7kqrl3rv	832	4	evidence	evidence	NN
cord-347298-7kqrl3rv	832	5	for	for	IN
cord-347298-7kqrl3rv	832	6	involvement	involvement	NN
cord-347298-7kqrl3rv	832	7	of	of	IN
cord-347298-7kqrl3rv	832	8	specific	specific	JJ
cord-347298-7kqrl3rv	832	9	G	g	NN
cord-347298-7kqrl3rv	832	10	-	-	HYPH
cord-347298-7kqrl3rv	832	11	protein	protein	NN
cord-347298-7kqrl3rv	832	12	-	-	HYPH
cord-347298-7kqrl3rv	832	13	coupled	couple	VBN
cord-347298-7kqrl3rv	832	14	receptors	receptor	NNS
cord-347298-7kqrl3rv	832	15	(	(	-LRB-
cord-347298-7kqrl3rv	832	16	Flemming	Flemming	NNP
cord-347298-7kqrl3rv	832	17	et	et	NNP
cord-347298-7kqrl3rv	832	18	al	al	NNP
cord-347298-7kqrl3rv	832	19	.	.	.
cord-347298-7kqrl3rv	832	20	2006	2006	CD
cord-347298-7kqrl3rv	832	21	;	;	:
cord-347298-7kqrl3rv	832	22	Lin	Lin	NNP
cord-347298-7kqrl3rv	832	23	and	and	CC
cord-347298-7kqrl3rv	832	24	Ye	Ye	NNP
cord-347298-7kqrl3rv	832	25	2003	2003	CD
cord-347298-7kqrl3rv	832	26	;	;	:
cord-347298-7kqrl3rv	832	27	Radu	Radu	NNP
cord-347298-7kqrl3rv	832	28	et	et	NNP
cord-347298-7kqrl3rv	832	29	al	al	NNP
cord-347298-7kqrl3rv	832	30	.	.	.
cord-347298-7kqrl3rv	832	31	2004	2004	CD
cord-347298-7kqrl3rv	833	1	;	;	:
cord-347298-7kqrl3rv	833	2	Soga	Soga	NNP
cord-347298-7kqrl3rv	833	3	et	et	NNP
cord-347298-7kqrl3rv	833	4	al	al	NNP
cord-347298-7kqrl3rv	833	5	.	.	.
cord-347298-7kqrl3rv	834	1	2005	2005	CD
cord-347298-7kqrl3rv	834	2	;	;	:
cord-347298-7kqrl3rv	834	3	Yang	Yang	NNP
cord-347298-7kqrl3rv	834	4	et	et	NNP
cord-347298-7kqrl3rv	834	5	al	al	NNP
cord-347298-7kqrl3rv	834	6	.	.	NNP
cord-347298-7kqrl3rv	834	7	2005	2005	CD
cord-347298-7kqrl3rv	834	8	)	)	-RRB-
cord-347298-7kqrl3rv	835	1	,	,	,
cord-347298-7kqrl3rv	835	2	LPCs	lpc	NNS
cord-347298-7kqrl3rv	835	3	may	may	MD
cord-347298-7kqrl3rv	835	4	interact	interact	VB
cord-347298-7kqrl3rv	835	5	with	with	IN
cord-347298-7kqrl3rv	835	6	G	g	NN
cord-347298-7kqrl3rv	835	7	-	-	HYPH
cord-347298-7kqrl3rv	835	8	proteins	protein	NNS
cord-347298-7kqrl3rv	835	9	,	,	,
cord-347298-7kqrl3rv	835	10	membrane	membrane	NN
cord-347298-7kqrl3rv	835	11	kinases	kinase	NNS
cord-347298-7kqrl3rv	835	12	,	,	,
cord-347298-7kqrl3rv	835	13	and	and	CC
cord-347298-7kqrl3rv	835	14	ion	ion	NN
cord-347298-7kqrl3rv	835	15	channels	channel	NNS
cord-347298-7kqrl3rv	835	16	directly	directly	RB
cord-347298-7kqrl3rv	835	17	,	,	,
cord-347298-7kqrl3rv	835	18	thereby	thereby	RB
cord-347298-7kqrl3rv	835	19	bypassing	bypass	VBG
cord-347298-7kqrl3rv	835	20	the	the	DT
cord-347298-7kqrl3rv	835	21	need	need	NN
cord-347298-7kqrl3rv	835	22	for	for	IN
cord-347298-7kqrl3rv	835	23	any	any	DT
cord-347298-7kqrl3rv	835	24	specific	specific	JJ
cord-347298-7kqrl3rv	835	25	receptor	receptor	NN
cord-347298-7kqrl3rv	835	26	-	-	HYPH
cord-347298-7kqrl3rv	835	27	ligand	ligand	NN
cord-347298-7kqrl3rv	835	28	interactions	interaction	NNS
cord-347298-7kqrl3rv	835	29	.	.	.
cord-347298-7kqrl3rv	836	1	The	the	DT
cord-347298-7kqrl3rv	836	2	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	836	3	fluid	fluid	NN
cord-347298-7kqrl3rv	836	4	of	of	IN
cord-347298-7kqrl3rv	836	5	the	the	DT
cord-347298-7kqrl3rv	836	6	testis	testis	NN
cord-347298-7kqrl3rv	836	7	has	have	VBZ
cord-347298-7kqrl3rv	836	8	long	long	RB
cord-347298-7kqrl3rv	836	9	been	be	VBN
cord-347298-7kqrl3rv	836	10	known	know	VBN
cord-347298-7kqrl3rv	836	11	to	to	TO
cord-347298-7kqrl3rv	836	12	possess	possess	VB
cord-347298-7kqrl3rv	836	13	potent	potent	JJ
cord-347298-7kqrl3rv	836	14	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	836	15	-	-	HYPH
cord-347298-7kqrl3rv	836	16	inhibiting	inhibit	VBG
cord-347298-7kqrl3rv	836	17	activity	activity	NN
cord-347298-7kqrl3rv	836	18	in	in	IN
cord-347298-7kqrl3rv	836	19	vitro	vitro	FW
cord-347298-7kqrl3rv	837	1	(	(	-LRB-
cord-347298-7kqrl3rv	837	2	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	837	3	et	et	NNP
cord-347298-7kqrl3rv	837	4	al	al	NNP
cord-347298-7kqrl3rv	837	5	.	.	.
cord-347298-7kqrl3rv	838	1	1998a	1998a	CD
cord-347298-7kqrl3rv	838	2	;	;	:
cord-347298-7kqrl3rv	838	3	Pöllänen	Pöllänen	NNP
cord-347298-7kqrl3rv	838	4	et	et	NNP
cord-347298-7kqrl3rv	838	5	al	al	NNP
cord-347298-7kqrl3rv	838	6	.	.	.
cord-347298-7kqrl3rv	838	7	1988	1988	CD
cord-347298-7kqrl3rv	838	8	)	)	-RRB-
cord-347298-7kqrl3rv	838	9	.	.	.
cord-347298-7kqrl3rv	839	1	The	the	DT
cord-347298-7kqrl3rv	839	2	molecules	molecule	NNS
cord-347298-7kqrl3rv	839	3	responsible	responsible	JJ
cord-347298-7kqrl3rv	839	4	for	for	IN
cord-347298-7kqrl3rv	839	5	this	this	DT
cord-347298-7kqrl3rv	839	6	activity	activity	NN
cord-347298-7kqrl3rv	839	7	have	have	VBP
cord-347298-7kqrl3rv	839	8	now	now	RB
cord-347298-7kqrl3rv	839	9	been	be	VBN
cord-347298-7kqrl3rv	839	10	isolated	isolate	VBN
cord-347298-7kqrl3rv	839	11	and	and	CC
cord-347298-7kqrl3rv	839	12	identified	identify	VBN
cord-347298-7kqrl3rv	839	13	as	as	IN
cord-347298-7kqrl3rv	839	14	the	the	DT
cord-347298-7kqrl3rv	839	15	specific	specific	JJ
cord-347298-7kqrl3rv	839	16	LPCs	lpc	NNS
cord-347298-7kqrl3rv	839	17	:	:	:
cord-347298-7kqrl3rv	839	18	1-palmitoyl	1-palmitoyl	CD
cord-347298-7kqrl3rv	839	19	-	-	HYPH
cord-347298-7kqrl3rv	839	20	sn	sn	NN
cord-347298-7kqrl3rv	839	21	-	-	HYPH
cord-347298-7kqrl3rv	839	22	glycero-3-phosphocholine	glycero-3-phosphocholine	NN
cord-347298-7kqrl3rv	839	23	(	(	-LRB-
cord-347298-7kqrl3rv	839	24	16:0a	16:0a	NNP
cord-347298-7kqrl3rv	839	25	-	-	HYPH
cord-347298-7kqrl3rv	839	26	LPC	LPC	NNP
cord-347298-7kqrl3rv	839	27	)	)	-RRB-
cord-347298-7kqrl3rv	839	28	,	,	,
cord-347298-7kqrl3rv	839	29	1-oleoyl	1-oleoyl	CD
cord-347298-7kqrl3rv	839	30	-	-	HYPH
cord-347298-7kqrl3rv	839	31	sn	sn	NN
cord-347298-7kqrl3rv	839	32	-	-	HYPH
cord-347298-7kqrl3rv	839	33	glycero-3-phosphocholine	glycero-3-phosphocholine	NN
cord-347298-7kqrl3rv	839	34	(	(	-LRB-
cord-347298-7kqrl3rv	839	35	18:1a	18:1a	CD
cord-347298-7kqrl3rv	839	36	-	-	HYPH
cord-347298-7kqrl3rv	839	37	LPC	LPC	NNP
cord-347298-7kqrl3rv	839	38	)	)	-RRB-
cord-347298-7kqrl3rv	839	39	,	,	,
cord-347298-7kqrl3rv	839	40	a	a	DT
cord-347298-7kqrl3rv	839	41	18:2a	18:2a	CD
cord-347298-7kqrl3rv	839	42	-	-	HYPH
cord-347298-7kqrl3rv	839	43	LPC	LPC	NNP
cord-347298-7kqrl3rv	839	44	(	(	-LRB-
cord-347298-7kqrl3rv	839	45	putatively	putatively	RB
cord-347298-7kqrl3rv	839	46	,	,	,
cord-347298-7kqrl3rv	839	47	1-linoleoylsn	1-linoleoylsn	CD
cord-347298-7kqrl3rv	839	48	-	-	HYPH
cord-347298-7kqrl3rv	839	49	glycero-3-phosphocholine	glycero-3-phosphocholine	NNP
cord-347298-7kqrl3rv	839	50	)	)	-RRB-
cord-347298-7kqrl3rv	839	51	,	,	,
cord-347298-7kqrl3rv	839	52	and	and	CC
cord-347298-7kqrl3rv	839	53	a	a	DT
cord-347298-7kqrl3rv	839	54	20:4a	20:4a	CD
cord-347298-7kqrl3rv	839	55	-	-	HYPH
cord-347298-7kqrl3rv	839	56	LPC	LPC	NNP
cord-347298-7kqrl3rv	839	57	(	(	-LRB-
cord-347298-7kqrl3rv	839	58	putatively	putatively	RB
cord-347298-7kqrl3rv	839	59	,	,	,
cord-347298-7kqrl3rv	839	60	1-arachidonyl	1-arachidonyl	CD
cord-347298-7kqrl3rv	839	61	-	-	HYPH
cord-347298-7kqrl3rv	839	62	sn	sn	NN
cord-347298-7kqrl3rv	839	63	-	-	HYPH
cord-347298-7kqrl3rv	839	64	glycero-3-phosphocholine	glycero-3-phosphocholine	NN
cord-347298-7kqrl3rv	839	65	)	)	-RRB-
cord-347298-7kqrl3rv	840	1	(	(	-LRB-
cord-347298-7kqrl3rv	840	2	Foulds	Foulds	NNP
cord-347298-7kqrl3rv	840	3	et	et	NNP
cord-347298-7kqrl3rv	840	4	al	al	NNP
cord-347298-7kqrl3rv	840	5	.	.	NNP
cord-347298-7kqrl3rv	840	6	2008	2008	CD
cord-347298-7kqrl3rv	840	7	)	)	-RRB-
cord-347298-7kqrl3rv	840	8	.	.	.
cord-347298-7kqrl3rv	841	1	These	these	DT
cord-347298-7kqrl3rv	841	2	molecules	molecule	NNS
cord-347298-7kqrl3rv	841	3	inhibit	inhibit	VBP
cord-347298-7kqrl3rv	841	4	T	t	NN
cord-347298-7kqrl3rv	841	5	cell	cell	NN
cord-347298-7kqrl3rv	841	6	proliferation	proliferation	NN
cord-347298-7kqrl3rv	841	7	in	in	IN
cord-347298-7kqrl3rv	841	8	response	response	NN
cord-347298-7kqrl3rv	841	9	to	to	TO
cord-347298-7kqrl3rv	841	10	activation	activation	NN
cord-347298-7kqrl3rv	841	11	and	and	CC
cord-347298-7kqrl3rv	841	12	induce	induce	VB
cord-347298-7kqrl3rv	841	13	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	841	14	of	of	IN
cord-347298-7kqrl3rv	841	15	these	these	DT
cord-347298-7kqrl3rv	841	16	cells	cell	NNS
cord-347298-7kqrl3rv	841	17	in	in	IN
cord-347298-7kqrl3rv	841	18	a	a	DT
cord-347298-7kqrl3rv	841	19	time	time	NN
cord-347298-7kqrl3rv	841	20	-	-	:
cord-347298-7kqrl3rv	841	21	and	and	CC
cord-347298-7kqrl3rv	841	22	dose	dose	NN
cord-347298-7kqrl3rv	841	23	-	-	HYPH
cord-347298-7kqrl3rv	841	24	dependent	dependent	JJ
cord-347298-7kqrl3rv	841	25	manner	manner	NN
cord-347298-7kqrl3rv	841	26	at	at	IN
cord-347298-7kqrl3rv	841	27	physiologically	physiologically	RB
cord-347298-7kqrl3rv	841	28	relevant	relevant	JJ
cord-347298-7kqrl3rv	841	29	concentrations	concentration	NNS
cord-347298-7kqrl3rv	841	30	.	.	.
cord-347298-7kqrl3rv	842	1	Although	although	IN
cord-347298-7kqrl3rv	842	2	PAF	PAF	NNP
cord-347298-7kqrl3rv	842	3	activity	activity	NN
cord-347298-7kqrl3rv	842	4	has	have	VBZ
cord-347298-7kqrl3rv	842	5	also	also	RB
cord-347298-7kqrl3rv	842	6	been	be	VBN
cord-347298-7kqrl3rv	842	7	found	find	VBN
cord-347298-7kqrl3rv	842	8	in	in	IN
cord-347298-7kqrl3rv	842	9	the	the	DT
cord-347298-7kqrl3rv	842	10	testis	testis	NN
cord-347298-7kqrl3rv	842	11	(	(	-LRB-
cord-347298-7kqrl3rv	842	12	Muguruma	Muguruma	NNP
cord-347298-7kqrl3rv	842	13	et	et	NNP
cord-347298-7kqrl3rv	842	14	al	al	NNP
cord-347298-7kqrl3rv	842	15	.	.	.
cord-347298-7kqrl3rv	842	16	1993	1993	CD
cord-347298-7kqrl3rv	842	17	)	)	-RRB-
cord-347298-7kqrl3rv	842	18	,	,	,
cord-347298-7kqrl3rv	842	19	these	these	DT
cord-347298-7kqrl3rv	842	20	acetylated	acetylated	JJ
cord-347298-7kqrl3rv	842	21	LPCs	lpc	NNS
cord-347298-7kqrl3rv	842	22	did	do	VBD
cord-347298-7kqrl3rv	842	23	not	not	RB
cord-347298-7kqrl3rv	842	24	appear	appear	VB
cord-347298-7kqrl3rv	842	25	to	to	TO
cord-347298-7kqrl3rv	842	26	contribute	contribute	VB
cord-347298-7kqrl3rv	842	27	significantly	significantly	RB
cord-347298-7kqrl3rv	842	28	to	to	IN
cord-347298-7kqrl3rv	842	29	the	the	DT
cord-347298-7kqrl3rv	842	30	T	T	NNP
cord-347298-7kqrl3rv	842	31	cell	cell	NN
cord-347298-7kqrl3rv	842	32	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	842	33	activity	activity	NN
cord-347298-7kqrl3rv	842	34	.	.	.
cord-347298-7kqrl3rv	843	1	The	the	DT
cord-347298-7kqrl3rv	843	2	emergence	emergence	NN
cord-347298-7kqrl3rv	843	3	of	of	IN
cord-347298-7kqrl3rv	843	4	LPCs	lpc	NNS
cord-347298-7kqrl3rv	843	5	as	as	IN
cord-347298-7kqrl3rv	843	6	regulators	regulator	NNS
cord-347298-7kqrl3rv	843	7	of	of	IN
cord-347298-7kqrl3rv	843	8	critical	critical	JJ
cord-347298-7kqrl3rv	843	9	immune	immune	JJ
cord-347298-7kqrl3rv	843	10	events	event	NNS
cord-347298-7kqrl3rv	843	11	in	in	IN
cord-347298-7kqrl3rv	843	12	the	the	DT
cord-347298-7kqrl3rv	843	13	testis	testis	NN
cord-347298-7kqrl3rv	843	14	opens	open	VBZ
cord-347298-7kqrl3rv	843	15	up	up	RP
cord-347298-7kqrl3rv	843	16	new	new	JJ
cord-347298-7kqrl3rv	843	17	avenues	avenue	NNS
cord-347298-7kqrl3rv	843	18	of	of	IN
cord-347298-7kqrl3rv	843	19	inquiry	inquiry	NN
cord-347298-7kqrl3rv	843	20	into	into	IN
cord-347298-7kqrl3rv	843	21	the	the	DT
cord-347298-7kqrl3rv	843	22	origins	origin	NNS
cord-347298-7kqrl3rv	843	23	of	of	IN
cord-347298-7kqrl3rv	843	24	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	843	25	infertility	infertility	NN
cord-347298-7kqrl3rv	843	26	and	and	CC
cord-347298-7kqrl3rv	843	27	more	more	JJR
cord-347298-7kqrl3rv	843	28	general	general	JJ
cord-347298-7kqrl3rv	843	29	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	843	30	of	of	IN
cord-347298-7kqrl3rv	843	31	peripheral	peripheral	JJ
cord-347298-7kqrl3rv	843	32	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	843	33	.	.	.
cord-347298-7kqrl3rv	844	1	These	these	DT
cord-347298-7kqrl3rv	844	2	molecules	molecule	NNS
cord-347298-7kqrl3rv	844	3	may	may	MD
cord-347298-7kqrl3rv	844	4	also	also	RB
cord-347298-7kqrl3rv	844	5	have	have	VB
cord-347298-7kqrl3rv	844	6	other	other	JJ
cord-347298-7kqrl3rv	844	7	roles	role	NNS
cord-347298-7kqrl3rv	844	8	in	in	IN
cord-347298-7kqrl3rv	844	9	testis	testis	NN
cord-347298-7kqrl3rv	844	10	biology	biology	NN
cord-347298-7kqrl3rv	844	11	that	that	WDT
cord-347298-7kqrl3rv	844	12	demand	demand	VBP
cord-347298-7kqrl3rv	844	13	consideration	consideration	NN
cord-347298-7kqrl3rv	844	14	.	.	.
cord-347298-7kqrl3rv	845	1	11.10.4.3.5	11.10.4.3.5	CD
cord-347298-7kqrl3rv	845	2	Cell	cell	NN
cord-347298-7kqrl3rv	845	3	surface	surface	NN
cord-347298-7kqrl3rv	845	4	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	845	5	molecules	molecule	NNS
cord-347298-7kqrl3rv	845	6	:	:	:
cord-347298-7kqrl3rv	846	1	Complement	complement	JJ
cord-347298-7kqrl3rv	846	2	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	846	3	and	and	CC
cord-347298-7kqrl3rv	846	4	nonclassical	nonclassical	JJ
cord-347298-7kqrl3rv	846	5	MHC	MHC	NNP
cord-347298-7kqrl3rv	846	6	Inhibition	Inhibition	NNP
cord-347298-7kqrl3rv	846	7	of	of	IN
cord-347298-7kqrl3rv	846	8	complement	complement	JJ
cord-347298-7kqrl3rv	846	9	activation	activation	NN
cord-347298-7kqrl3rv	846	10	is	be	VBZ
cord-347298-7kqrl3rv	846	11	an	an	DT
cord-347298-7kqrl3rv	846	12	important	important	JJ
cord-347298-7kqrl3rv	846	13	mechanism	mechanism	NN
cord-347298-7kqrl3rv	846	14	for	for	IN
cord-347298-7kqrl3rv	846	15	reducing	reduce	VBG
cord-347298-7kqrl3rv	846	16	transplant	transplant	NN
cord-347298-7kqrl3rv	846	17	rejection	rejection	NN
cord-347298-7kqrl3rv	846	18	,	,	,
cord-347298-7kqrl3rv	846	19	particularly	particularly	RB
cord-347298-7kqrl3rv	846	20	in	in	IN
cord-347298-7kqrl3rv	846	21	the	the	DT
cord-347298-7kqrl3rv	846	22	early	early	JJ
cord-347298-7kqrl3rv	846	23	phase	phase	NN
cord-347298-7kqrl3rv	846	24	.	.	.
cord-347298-7kqrl3rv	847	1	Membrane	membrane	NN
cord-347298-7kqrl3rv	847	2	complement	complement	NN
cord-347298-7kqrl3rv	847	3	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	847	4	,	,	,
cord-347298-7kqrl3rv	847	5	such	such	JJ
cord-347298-7kqrl3rv	847	6	as	as	IN
cord-347298-7kqrl3rv	847	7	CD46	CD46	NNP
cord-347298-7kqrl3rv	847	8	,	,	,
cord-347298-7kqrl3rv	847	9	CD55	CD55	NNP
cord-347298-7kqrl3rv	847	10	,	,	,
cord-347298-7kqrl3rv	847	11	CD59	CD59	NNP
cord-347298-7kqrl3rv	847	12	,	,	,
cord-347298-7kqrl3rv	847	13	and	and	CC
cord-347298-7kqrl3rv	847	14	the	the	DT
cord-347298-7kqrl3rv	847	15	complement	complement	JJ
cord-347298-7kqrl3rv	847	16	receptor	receptor	NN
cord-347298-7kqrl3rv	847	17	-	-	HYPH
cord-347298-7kqrl3rv	847	18	related	relate	VBN
cord-347298-7kqrl3rv	847	19	protein	protein	NN
cord-347298-7kqrl3rv	847	20	(	(	-LRB-
cord-347298-7kqrl3rv	847	21	Crry	Crry	NNP
cord-347298-7kqrl3rv	847	22	)	)	-RRB-
cord-347298-7kqrl3rv	847	23	,	,	,
cord-347298-7kqrl3rv	847	24	are	be	VBP
cord-347298-7kqrl3rv	847	25	expressed	express	VBN
cord-347298-7kqrl3rv	847	26	in	in	IN
cord-347298-7kqrl3rv	847	27	several	several	JJ
cord-347298-7kqrl3rv	847	28	immune	immune	NN
cord-347298-7kqrl3rv	847	29	-	-	HYPH
cord-347298-7kqrl3rv	847	30	privileged	privileged	JJ
cord-347298-7kqrl3rv	847	31	tissues	tissue	NNS
cord-347298-7kqrl3rv	847	32	and	and	CC
cord-347298-7kqrl3rv	847	33	have	have	VBP
cord-347298-7kqrl3rv	847	34	been	be	VBN
cord-347298-7kqrl3rv	847	35	implicated	implicate	VBN
cord-347298-7kqrl3rv	847	36	in	in	IN
cord-347298-7kqrl3rv	847	37	suppression	suppression	NN
cord-347298-7kqrl3rv	847	38	of	of	IN
cord-347298-7kqrl3rv	847	39	inflammation	inflammation	NN
cord-347298-7kqrl3rv	847	40	in	in	IN
cord-347298-7kqrl3rv	847	41	the	the	DT
cord-347298-7kqrl3rv	847	42	eye	eye	NN
cord-347298-7kqrl3rv	847	43	and	and	CC
cord-347298-7kqrl3rv	847	44	placenta	placenta	NN
cord-347298-7kqrl3rv	848	1	(	(	-LRB-
cord-347298-7kqrl3rv	848	2	Bora	Bora	NNP
cord-347298-7kqrl3rv	848	3	et	et	NNP
cord-347298-7kqrl3rv	848	4	al	al	NNP
cord-347298-7kqrl3rv	848	5	.	.	.
cord-347298-7kqrl3rv	848	6	1993	1993	CD
cord-347298-7kqrl3rv	849	1	;	;	:
cord-347298-7kqrl3rv	849	2	Bulla	Bulla	NNP
cord-347298-7kqrl3rv	849	3	et	et	NNP
cord-347298-7kqrl3rv	849	4	al	al	NNP
cord-347298-7kqrl3rv	849	5	.	.	NNP
cord-347298-7kqrl3rv	849	6	2005	2005	CD
cord-347298-7kqrl3rv	849	7	)	)	-RRB-
cord-347298-7kqrl3rv	849	8	.	.	.
cord-347298-7kqrl3rv	850	1	CD46	CD46	NNP
cord-347298-7kqrl3rv	851	1	and	and	CC
cord-347298-7kqrl3rv	851	2	CD55	CD55	NNP
cord-347298-7kqrl3rv	851	3	appear	appear	VBP
cord-347298-7kqrl3rv	851	4	to	to	TO
cord-347298-7kqrl3rv	851	5	be	be	VB
cord-347298-7kqrl3rv	851	6	confined	confine	VBN
cord-347298-7kqrl3rv	851	7	to	to	IN
cord-347298-7kqrl3rv	851	8	spermatids	spermatid	NNS
cord-347298-7kqrl3rv	851	9	in	in	IN
cord-347298-7kqrl3rv	851	10	the	the	DT
cord-347298-7kqrl3rv	851	11	adult	adult	NN
cord-347298-7kqrl3rv	851	12	rat	rat	NN
cord-347298-7kqrl3rv	851	13	testis	testis	NN
cord-347298-7kqrl3rv	852	1	,	,	,
cord-347298-7kqrl3rv	852	2	Crry	Crry	NNP
cord-347298-7kqrl3rv	852	3	is	be	VBZ
cord-347298-7kqrl3rv	852	4	expressed	express	VBN
cord-347298-7kqrl3rv	852	5	on	on	IN
cord-347298-7kqrl3rv	852	6	early	early	JJ
cord-347298-7kqrl3rv	852	7	spermatocytes	spermatocyte	NNS
cord-347298-7kqrl3rv	852	8	and	and	CC
cord-347298-7kqrl3rv	852	9	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	852	10	cells	cell	NNS
cord-347298-7kqrl3rv	852	11	,	,	,
cord-347298-7kqrl3rv	852	12	but	but	CC
cord-347298-7kqrl3rv	852	13	CD59	CD59	NNP
cord-347298-7kqrl3rv	852	14	is	be	VBZ
cord-347298-7kqrl3rv	852	15	widely	widely	RB
cord-347298-7kqrl3rv	852	16	expressed	express	VBN
cord-347298-7kqrl3rv	852	17	throughout	throughout	IN
cord-347298-7kqrl3rv	852	18	the	the	DT
cord-347298-7kqrl3rv	852	19	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	852	20	epithelium	epithelium	NN
cord-347298-7kqrl3rv	852	21	and	and	CC
cord-347298-7kqrl3rv	852	22	interstitium	interstitium	NN
cord-347298-7kqrl3rv	852	23	.	.	.
cord-347298-7kqrl3rv	853	1	A	a	DT
cord-347298-7kqrl3rv	853	2	role	role	NN
cord-347298-7kqrl3rv	853	3	for	for	IN
cord-347298-7kqrl3rv	853	4	CD59	CD59	NNP
cord-347298-7kqrl3rv	853	5	expression	expression	NN
cord-347298-7kqrl3rv	853	6	by	by	IN
cord-347298-7kqrl3rv	853	7	the	the	DT
cord-347298-7kqrl3rv	853	8	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	853	9	cells	cell	NNS
cord-347298-7kqrl3rv	853	10	in	in	IN
cord-347298-7kqrl3rv	853	11	prolonging	prolong	VBG
cord-347298-7kqrl3rv	853	12	the	the	DT
cord-347298-7kqrl3rv	853	13	survival	survival	NN
cord-347298-7kqrl3rv	853	14	of	of	IN
cord-347298-7kqrl3rv	853	15	these	these	DT
cord-347298-7kqrl3rv	853	16	cells	cell	NNS
cord-347298-7kqrl3rv	853	17	in	in	IN
cord-347298-7kqrl3rv	853	18	transplantation	transplantation	NN
cord-347298-7kqrl3rv	853	19	studies	study	NNS
cord-347298-7kqrl3rv	853	20	has	have	VBZ
cord-347298-7kqrl3rv	853	21	been	be	VBN
cord-347298-7kqrl3rv	853	22	suggested	suggest	VBN
cord-347298-7kqrl3rv	853	23	.	.	.
cord-347298-7kqrl3rv	854	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	854	2	,	,	,
cord-347298-7kqrl3rv	854	3	complement	complement	VB
cord-347298-7kqrl3rv	854	4	regulators	regulator	NNS
cord-347298-7kqrl3rv	854	5	both	both	DT
cord-347298-7kqrl3rv	854	6	in	in	IN
cord-347298-7kqrl3rv	854	7	seminal	seminal	JJ
cord-347298-7kqrl3rv	854	8	plasma	plasma	NN
cord-347298-7kqrl3rv	854	9	and	and	CC
cord-347298-7kqrl3rv	854	10	on	on	IN
cord-347298-7kqrl3rv	854	11	the	the	DT
cord-347298-7kqrl3rv	854	12	surface	surface	NN
cord-347298-7kqrl3rv	854	13	of	of	IN
cord-347298-7kqrl3rv	854	14	the	the	DT
cord-347298-7kqrl3rv	854	15	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	854	16	(	(	-LRB-
cord-347298-7kqrl3rv	854	17	CD46	CD46	NNP
cord-347298-7kqrl3rv	854	18	,	,	,
cord-347298-7kqrl3rv	854	19	CD55	CD55	NNP
cord-347298-7kqrl3rv	854	20	,	,	,
cord-347298-7kqrl3rv	854	21	and	and	CC
cord-347298-7kqrl3rv	854	22	CD59	CD59	NNP
cord-347298-7kqrl3rv	854	23	)	)	-RRB-
cord-347298-7kqrl3rv	854	24	may	may	MD
cord-347298-7kqrl3rv	854	25	contribute	contribute	VB
cord-347298-7kqrl3rv	854	26	to	to	TO
cord-347298-7kqrl3rv	854	27	complement	complement	JJ
cord-347298-7kqrl3rv	854	28	evasion	evasion	NN
cord-347298-7kqrl3rv	854	29	by	by	IN
cord-347298-7kqrl3rv	854	30	the	the	DT
cord-347298-7kqrl3rv	854	31	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	854	32	in	in	IN
cord-347298-7kqrl3rv	854	33	the	the	DT
cord-347298-7kqrl3rv	854	34	female	female	JJ
cord-347298-7kqrl3rv	854	35	tract	tract	NN
cord-347298-7kqrl3rv	854	36	.	.	.
cord-347298-7kqrl3rv	855	1	Classical	classical	JJ
cord-347298-7kqrl3rv	855	2	MHC	MHC	NNP
cord-347298-7kqrl3rv	855	3	class	class	NN
cord-347298-7kqrl3rv	856	1	I	-PRON-	PRP
cord-347298-7kqrl3rv	856	2	molecules	molecule	NNS
cord-347298-7kqrl3rv	857	1	(	(	-LRB-
cord-347298-7kqrl3rv	857	2	HLA	HLA	NNP
cord-347298-7kqrl3rv	857	3	-	-	HYPH
cord-347298-7kqrl3rv	857	4	A	A	NNP
cord-347298-7kqrl3rv	857	5	,	,	,
cord-347298-7kqrl3rv	857	6	HLA	HLA	NNP
cord-347298-7kqrl3rv	857	7	-	-	HYPH
cord-347298-7kqrl3rv	857	8	B	B	NNP
cord-347298-7kqrl3rv	857	9	,	,	,
cord-347298-7kqrl3rv	857	10	and	and	CC
cord-347298-7kqrl3rv	857	11	HLA	HLA	NNP
cord-347298-7kqrl3rv	857	12	-	-	HYPH
cord-347298-7kqrl3rv	857	13	C	C	NNP
cord-347298-7kqrl3rv	857	14	)	)	-RRB-
cord-347298-7kqrl3rv	857	15	are	be	VBP
cord-347298-7kqrl3rv	857	16	expressed	express	VBN
cord-347298-7kqrl3rv	857	17	on	on	IN
cord-347298-7kqrl3rv	857	18	nearly	nearly	RB
cord-347298-7kqrl3rv	857	19	all	all	DT
cord-347298-7kqrl3rv	857	20	cell	cell	NN
cord-347298-7kqrl3rv	857	21	types	type	NNS
cord-347298-7kqrl3rv	857	22	,	,	,
cord-347298-7kqrl3rv	857	23	and	and	CC
cord-347298-7kqrl3rv	857	24	facilitate	facilitate	VB
cord-347298-7kqrl3rv	857	25	antigen	antigen	NN
cord-347298-7kqrl3rv	857	26	presentation	presentation	NN
cord-347298-7kqrl3rv	857	27	by	by	IN
cord-347298-7kqrl3rv	857	28	these	these	DT
cord-347298-7kqrl3rv	857	29	cells	cell	NNS
cord-347298-7kqrl3rv	857	30	and	and	CC
cord-347298-7kqrl3rv	857	31	activation	activation	NN
cord-347298-7kqrl3rv	857	32	of	of	IN
cord-347298-7kqrl3rv	857	33	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	857	34	T	t	NN
cord-347298-7kqrl3rv	857	35	cells	cell	NNS
cord-347298-7kqrl3rv	857	36	(	(	-LRB-
cord-347298-7kqrl3rv	857	37	Cresswell	Cresswell	NNP
cord-347298-7kqrl3rv	857	38	et	et	FW
cord-347298-7kqrl3rv	857	39	al	al	NNP
cord-347298-7kqrl3rv	857	40	.	.	.
cord-347298-7kqrl3rv	858	1	1999	1999	CD
cord-347298-7kqrl3rv	858	2	;	;	:
cord-347298-7kqrl3rv	858	3	Janeway	Janeway	NNP
cord-347298-7kqrl3rv	858	4	1992	1992	CD
cord-347298-7kqrl3rv	858	5	;	;	:
cord-347298-7kqrl3rv	858	6	Sant	Sant	NNP
cord-347298-7kqrl3rv	858	7	et	et	FW
cord-347298-7kqrl3rv	858	8	al	al	NNP
cord-347298-7kqrl3rv	858	9	.	.	.
cord-347298-7kqrl3rv	858	10	1999	1999	CD
cord-347298-7kqrl3rv	858	11	)	)	-RRB-
cord-347298-7kqrl3rv	858	12	.	.	.
cord-347298-7kqrl3rv	859	1	By	by	IN
cord-347298-7kqrl3rv	859	2	contrast	contrast	NN
cord-347298-7kqrl3rv	859	3	,	,	,
cord-347298-7kqrl3rv	859	4	the	the	DT
cord-347298-7kqrl3rv	859	5	nonclassical	nonclassical	JJ
cord-347298-7kqrl3rv	859	6	MHC	MHC	NNP
cord-347298-7kqrl3rv	859	7	class	class	NN
cord-347298-7kqrl3rv	859	8	Ib	Ib	NNP
cord-347298-7kqrl3rv	859	9	molecules	molecule	NNS
cord-347298-7kqrl3rv	859	10	(	(	-LRB-
cord-347298-7kqrl3rv	859	11	HLA	HLA	NNP
cord-347298-7kqrl3rv	859	12	-	-	HYPH
cord-347298-7kqrl3rv	859	13	E	E	NNP
cord-347298-7kqrl3rv	859	14	,	,	,
cord-347298-7kqrl3rv	859	15	-F	-f	ADD
cord-347298-7kqrl3rv	859	16	,	,	,
cord-347298-7kqrl3rv	859	17	and	and	CC
cord-347298-7kqrl3rv	859	18	-G	-G	JJR
cord-347298-7kqrl3rv	859	19	)	)	-RRB-
cord-347298-7kqrl3rv	859	20	are	be	VBP
cord-347298-7kqrl3rv	859	21	much	much	RB
cord-347298-7kqrl3rv	859	22	less	less	RBR
cord-347298-7kqrl3rv	859	23	widely	widely	RB
cord-347298-7kqrl3rv	859	24	expressed	express	VBN
cord-347298-7kqrl3rv	859	25	,	,	,
cord-347298-7kqrl3rv	859	26	and	and	CC
cord-347298-7kqrl3rv	859	27	are	be	VBP
cord-347298-7kqrl3rv	859	28	associated	associate	VBN
cord-347298-7kqrl3rv	859	29	with	with	IN
cord-347298-7kqrl3rv	859	30	suppression	suppression	NN
cord-347298-7kqrl3rv	859	31	of	of	IN
cord-347298-7kqrl3rv	859	32	the	the	DT
cord-347298-7kqrl3rv	859	33	adaptive	adaptive	JJ
cord-347298-7kqrl3rv	859	34	immune	immune	JJ
cord-347298-7kqrl3rv	859	35	response	response	NN
cord-347298-7kqrl3rv	859	36	.	.	.
cord-347298-7kqrl3rv	860	1	Membrane	membrane	NN
cord-347298-7kqrl3rv	860	2	-	-	HYPH
cord-347298-7kqrl3rv	860	3	bound	bind	VBN
cord-347298-7kqrl3rv	860	4	and	and	CC
cord-347298-7kqrl3rv	860	5	soluble	soluble	JJ
cord-347298-7kqrl3rv	860	6	variants	variant	NNS
cord-347298-7kqrl3rv	860	7	of	of	IN
cord-347298-7kqrl3rv	860	8	these	these	DT
cord-347298-7kqrl3rv	860	9	MHC	MHC	NNP
cord-347298-7kqrl3rv	860	10	class	class	NN
cord-347298-7kqrl3rv	860	11	Ib	Ib	NNP
cord-347298-7kqrl3rv	860	12	molecules	molecule	NNS
cord-347298-7kqrl3rv	860	13	have	have	VBP
cord-347298-7kqrl3rv	860	14	been	be	VBN
cord-347298-7kqrl3rv	860	15	implicated	implicate	VBN
cord-347298-7kqrl3rv	860	16	in	in	IN
cord-347298-7kqrl3rv	860	17	the	the	DT
cord-347298-7kqrl3rv	860	18	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	860	19	of	of	IN
cord-347298-7kqrl3rv	860	20	alloreactive	alloreactive	JJ
cord-347298-7kqrl3rv	860	21	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	860	22	T	t	NN
cord-347298-7kqrl3rv	860	23	cells	cell	NNS
cord-347298-7kqrl3rv	860	24	,	,	,
cord-347298-7kqrl3rv	860	25	inhibition	inhibition	NN
cord-347298-7kqrl3rv	860	26	of	of	IN
cord-347298-7kqrl3rv	860	27	NK	NK	NNP
cord-347298-7kqrl3rv	860	28	cell	cell	NN
cord-347298-7kqrl3rv	860	29	cytolytic	cytolytic	NN
cord-347298-7kqrl3rv	860	30	activity	activity	NN
cord-347298-7kqrl3rv	860	31	,	,	,
cord-347298-7kqrl3rv	860	32	suppression	suppression	NN
cord-347298-7kqrl3rv	860	33	of	of	IN
cord-347298-7kqrl3rv	860	34	T	T	NNP
cord-347298-7kqrl3rv	860	35	cell	cell	NN
cord-347298-7kqrl3rv	860	36	proliferation	proliferation	NN
cord-347298-7kqrl3rv	860	37	,	,	,
cord-347298-7kqrl3rv	860	38	and	and	CC
cord-347298-7kqrl3rv	860	39	deviation	deviation	NN
cord-347298-7kqrl3rv	860	40	of	of	IN
cord-347298-7kqrl3rv	860	41	type	type	NN
cord-347298-7kqrl3rv	860	42	1	1	CD
cord-347298-7kqrl3rv	860	43	to	to	TO
cord-347298-7kqrl3rv	860	44	type	type	VB
cord-347298-7kqrl3rv	860	45	2	2	CD
cord-347298-7kqrl3rv	860	46	responses	response	NNS
cord-347298-7kqrl3rv	860	47	,	,	,
cord-347298-7kqrl3rv	860	48	most	most	RBS
cord-347298-7kqrl3rv	860	49	notably	notably	RB
cord-347298-7kqrl3rv	860	50	in	in	IN
cord-347298-7kqrl3rv	860	51	pregnancy	pregnancy	NN
cord-347298-7kqrl3rv	860	52	(	(	-LRB-
cord-347298-7kqrl3rv	860	53	Bainbridge	Bainbridge	NNP
cord-347298-7kqrl3rv	860	54	et	et	NNP
cord-347298-7kqrl3rv	860	55	al	al	NNP
cord-347298-7kqrl3rv	860	56	.	.	.
cord-347298-7kqrl3rv	860	57	2000	2000	CD
cord-347298-7kqrl3rv	860	58	;	;	:
cord-347298-7kqrl3rv	861	1	Fournel	Fournel	NNP
cord-347298-7kqrl3rv	861	2	et	et	FW
cord-347298-7kqrl3rv	861	3	al	al	NNP
cord-347298-7kqrl3rv	861	4	.	.	.
cord-347298-7kqrl3rv	862	1	2000	2000	CD
cord-347298-7kqrl3rv	862	2	;	;	:
cord-347298-7kqrl3rv	862	3	Ishitani	Ishitani	NNP
cord-347298-7kqrl3rv	862	4	et	et	NNP
cord-347298-7kqrl3rv	862	5	al	al	NNP
cord-347298-7kqrl3rv	862	6	.	.	.
cord-347298-7kqrl3rv	863	1	2006	2006	CD
cord-347298-7kqrl3rv	864	1	;	;	:
cord-347298-7kqrl3rv	864	2	Kapasi	Kapasi	NNP
cord-347298-7kqrl3rv	864	3	et	et	NNP
cord-347298-7kqrl3rv	864	4	al	al	NNP
cord-347298-7kqrl3rv	864	5	.	.	.
cord-347298-7kqrl3rv	865	1	2000	2000	CD
cord-347298-7kqrl3rv	865	2	;	;	:
cord-347298-7kqrl3rv	865	3	Kanai	Kanai	NNP
cord-347298-7kqrl3rv	865	4	et	et	NNP
cord-347298-7kqrl3rv	865	5	al	al	NNP
cord-347298-7kqrl3rv	865	6	.	.	NNP
cord-347298-7kqrl3rv	865	7	2001	2001	CD
cord-347298-7kqrl3rv	865	8	;	;	:
cord-347298-7kqrl3rv	865	9	Riteau	Riteau	NNP
cord-347298-7kqrl3rv	865	10	et	et	NNP
cord-347298-7kqrl3rv	865	11	al	al	NNP
cord-347298-7kqrl3rv	865	12	.	.	.
cord-347298-7kqrl3rv	865	13	1999	1999	CD
cord-347298-7kqrl3rv	865	14	)	)	-RRB-
cord-347298-7kqrl3rv	865	15	.	.	.
cord-347298-7kqrl3rv	866	1	HLA	HLA	NNP
cord-347298-7kqrl3rv	866	2	-	-	HYPH
cord-347298-7kqrl3rv	866	3	G	G	NNP
cord-347298-7kqrl3rv	866	4	has	have	VBZ
cord-347298-7kqrl3rv	866	5	been	be	VBN
cord-347298-7kqrl3rv	866	6	found	find	VBN
cord-347298-7kqrl3rv	866	7	in	in	IN
cord-347298-7kqrl3rv	866	8	the	the	DT
cord-347298-7kqrl3rv	866	9	rhesus	rhesus	NNP
cord-347298-7kqrl3rv	866	10	monkey	monkey	NN
cord-347298-7kqrl3rv	866	11	testis	testis	NN
cord-347298-7kqrl3rv	866	12	(	(	-LRB-
cord-347298-7kqrl3rv	866	13	Ryan	Ryan	NNP
cord-347298-7kqrl3rv	866	14	et	et	NNP
cord-347298-7kqrl3rv	866	15	al	al	NNP
cord-347298-7kqrl3rv	866	16	.	.	.
cord-347298-7kqrl3rv	866	17	2002	2002	CD
cord-347298-7kqrl3rv	866	18	;	;	:
cord-347298-7kqrl3rv	867	1	Slukvin	Slukvin	NNP
cord-347298-7kqrl3rv	867	2	et	et	NNP
cord-347298-7kqrl3rv	867	3	al	al	NNP
cord-347298-7kqrl3rv	867	4	.	.	.
cord-347298-7kqrl3rv	867	5	1999	1999	CD
cord-347298-7kqrl3rv	867	6	)	)	-RRB-
cord-347298-7kqrl3rv	867	7	,	,	,
cord-347298-7kqrl3rv	867	8	and	and	CC
cord-347298-7kqrl3rv	867	9	HLA	HLA	NNP
cord-347298-7kqrl3rv	867	10	-	-	HYPH
cord-347298-7kqrl3rv	867	11	E	E	NNP
cord-347298-7kqrl3rv	867	12	is	be	VBZ
cord-347298-7kqrl3rv	867	13	expressed	express	VBN
cord-347298-7kqrl3rv	867	14	on	on	IN
cord-347298-7kqrl3rv	867	15	germ	germ	NN
cord-347298-7kqrl3rv	867	16	cells	cell	NNS
cord-347298-7kqrl3rv	867	17	in	in	IN
cord-347298-7kqrl3rv	867	18	the	the	DT
cord-347298-7kqrl3rv	867	19	human	human	JJ
cord-347298-7kqrl3rv	867	20	testis	testis	NN
cord-347298-7kqrl3rv	867	21	(	(	-LRB-
cord-347298-7kqrl3rv	867	22	Fiszer	Fiszer	NNP
cord-347298-7kqrl3rv	867	23	et	et	NNP
cord-347298-7kqrl3rv	867	24	al	al	NNP
cord-347298-7kqrl3rv	867	25	.	.	.
cord-347298-7kqrl3rv	867	26	1997	1997	CD
cord-347298-7kqrl3rv	867	27	)	)	-RRB-
cord-347298-7kqrl3rv	867	28	,	,	.
cord-347298-7kqrl3rv	868	1	indicating	indicate	VBG
cord-347298-7kqrl3rv	868	2	that	that	IN
cord-347298-7kqrl3rv	868	3	these	these	DT
cord-347298-7kqrl3rv	868	4	molecules	molecule	NNS
cord-347298-7kqrl3rv	868	5	may	may	MD
cord-347298-7kqrl3rv	868	6	contribute	contribute	VB
cord-347298-7kqrl3rv	868	7	to	to	IN
cord-347298-7kqrl3rv	868	8	immune	immune	JJ
cord-347298-7kqrl3rv	868	9	privilege	privilege	NN
cord-347298-7kqrl3rv	868	10	in	in	IN
cord-347298-7kqrl3rv	868	11	the	the	DT
cord-347298-7kqrl3rv	868	12	testis	testis	NN
cord-347298-7kqrl3rv	868	13	.	.	.
cord-347298-7kqrl3rv	869	1	From	from	IN
cord-347298-7kqrl3rv	869	2	the	the	DT
cord-347298-7kqrl3rv	869	3	evidence	evidence	NN
cord-347298-7kqrl3rv	869	4	outlined	outline	VBN
cord-347298-7kqrl3rv	869	5	in	in	IN
cord-347298-7kqrl3rv	869	6	the	the	DT
cord-347298-7kqrl3rv	869	7	previous	previous	JJ
cord-347298-7kqrl3rv	869	8	sections	section	NNS
cord-347298-7kqrl3rv	869	9	,	,	,
cord-347298-7kqrl3rv	869	10	it	-PRON-	PRP
cord-347298-7kqrl3rv	869	11	should	should	MD
cord-347298-7kqrl3rv	869	12	be	be	VB
cord-347298-7kqrl3rv	869	13	evident	evident	JJ
cord-347298-7kqrl3rv	869	14	that	that	IN
cord-347298-7kqrl3rv	869	15	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	869	16	and	and	CC
cord-347298-7kqrl3rv	869	17	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	869	18	processes	process	NNS
cord-347298-7kqrl3rv	869	19	are	be	VBP
cord-347298-7kqrl3rv	869	20	involved	involve	VBN
cord-347298-7kqrl3rv	869	21	in	in	IN
cord-347298-7kqrl3rv	869	22	both	both	DT
cord-347298-7kqrl3rv	869	23	normal	normal	JJ
cord-347298-7kqrl3rv	869	24	testicular	testicular	JJ
cord-347298-7kqrl3rv	869	25	function	function	NN
cord-347298-7kqrl3rv	869	26	and	and	CC
cord-347298-7kqrl3rv	869	27	testicular	testicular	JJ
cord-347298-7kqrl3rv	869	28	pathophysiology	pathophysiology	NN
cord-347298-7kqrl3rv	869	29	.	.	.
cord-347298-7kqrl3rv	870	1	In	in	IN
cord-347298-7kqrl3rv	870	2	the	the	DT
cord-347298-7kqrl3rv	870	3	normal	normal	JJ
cord-347298-7kqrl3rv	870	4	testis	testis	NN
cord-347298-7kqrl3rv	870	5	,	,	,
cord-347298-7kqrl3rv	870	6	roles	role	NNS
cord-347298-7kqrl3rv	870	7	in	in	IN
cord-347298-7kqrl3rv	870	8	the	the	DT
cord-347298-7kqrl3rv	870	9	maintenance	maintenance	NN
cord-347298-7kqrl3rv	870	10	of	of	IN
cord-347298-7kqrl3rv	870	11	immune	immune	JJ
cord-347298-7kqrl3rv	870	12	privilege	privilege	NN
cord-347298-7kqrl3rv	870	13	,	,	,
cord-347298-7kqrl3rv	870	14	the	the	DT
cord-347298-7kqrl3rv	870	15	control	control	NN
cord-347298-7kqrl3rv	870	16	of	of	IN
cord-347298-7kqrl3rv	870	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	870	18	cell	cell	NN
cord-347298-7kqrl3rv	870	19	development	development	NN
cord-347298-7kqrl3rv	870	20	,	,	,
cord-347298-7kqrl3rv	870	21	and	and	CC
cord-347298-7kqrl3rv	870	22	the	the	DT
cord-347298-7kqrl3rv	870	23	fine	fine	JJ
cord-347298-7kqrl3rv	870	24	regulation	regulation	NN
cord-347298-7kqrl3rv	870	25	of	of	IN
cord-347298-7kqrl3rv	870	26	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	870	27	are	be	VBP
cord-347298-7kqrl3rv	870	28	indicated	indicate	VBN
cord-347298-7kqrl3rv	870	29	(	(	-LRB-
cord-347298-7kqrl3rv	870	30	Figure	figure	NN
cord-347298-7kqrl3rv	870	31	4	4	CD
cord-347298-7kqrl3rv	870	32	)	)	-RRB-
cord-347298-7kqrl3rv	870	33	.	.	.
cord-347298-7kqrl3rv	871	1	Contributions	contribution	NNS
cord-347298-7kqrl3rv	871	2	to	to	IN
cord-347298-7kqrl3rv	871	3	pathology	pathology	NN
cord-347298-7kqrl3rv	871	4	include	include	VBP
cord-347298-7kqrl3rv	871	5	the	the	DT
cord-347298-7kqrl3rv	871	6	development	development	NN
cord-347298-7kqrl3rv	871	7	of	of	IN
cord-347298-7kqrl3rv	871	8	autoimmunity	autoimmunity	NN
cord-347298-7kqrl3rv	871	9	within	within	IN
cord-347298-7kqrl3rv	871	10	the	the	DT
cord-347298-7kqrl3rv	871	11	Inflammatory	Inflammatory	NNP
cord-347298-7kqrl3rv	871	12	and	and	CC
cord-347298-7kqrl3rv	871	13	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	871	14	signaling	signal	VBG
cord-347298-7kqrl3rv	871	15	in	in	IN
cord-347298-7kqrl3rv	871	16	the	the	DT
cord-347298-7kqrl3rv	871	17	control	control	NN
cord-347298-7kqrl3rv	871	18	of	of	IN
cord-347298-7kqrl3rv	871	19	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	871	20	interactions	interaction	NNS
cord-347298-7kqrl3rv	871	21	.	.	.
cord-347298-7kqrl3rv	872	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	872	2	cells	cell	NNS
cord-347298-7kqrl3rv	872	3	are	be	VBP
cord-347298-7kqrl3rv	872	4	primarily	primarily	RB
cord-347298-7kqrl3rv	872	5	regulated	regulate	VBN
cord-347298-7kqrl3rv	872	6	by	by	IN
cord-347298-7kqrl3rv	872	7	the	the	DT
cord-347298-7kqrl3rv	872	8	hormones	hormone	NNS
cord-347298-7kqrl3rv	872	9	follicle	follicle	NN
cord-347298-7kqrl3rv	872	10	-	-	HYPH
cord-347298-7kqrl3rv	872	11	stimulating	stimulate	VBG
cord-347298-7kqrl3rv	872	12	hormone	hormone	NN
cord-347298-7kqrl3rv	872	13	(	(	-LRB-
cord-347298-7kqrl3rv	872	14	FSH	fsh	NN
cord-347298-7kqrl3rv	872	15	)	)	-RRB-
cord-347298-7kqrl3rv	872	16	and	and	CC
cord-347298-7kqrl3rv	872	17	testosterone	testosterone	NN
cord-347298-7kqrl3rv	872	18	,	,	,
cord-347298-7kqrl3rv	872	19	the	the	DT
cord-347298-7kqrl3rv	872	20	latter	latter	JJ
cord-347298-7kqrl3rv	872	21	being	be	VBG
cord-347298-7kqrl3rv	872	22	produced	produce	VBN
cord-347298-7kqrl3rv	872	23	by	by	IN
cord-347298-7kqrl3rv	872	24	the	the	DT
cord-347298-7kqrl3rv	872	25	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	872	26	cells	cell	NNS
cord-347298-7kqrl3rv	872	27	on	on	IN
cord-347298-7kqrl3rv	872	28	stimulation	stimulation	NN
cord-347298-7kqrl3rv	872	29	by	by	IN
cord-347298-7kqrl3rv	872	30	luteinizing	luteinize	VBG
cord-347298-7kqrl3rv	872	31	hormone	hormone	NN
cord-347298-7kqrl3rv	872	32	(	(	-LRB-
cord-347298-7kqrl3rv	872	33	LH	LH	NNP
cord-347298-7kqrl3rv	872	34	)	)	-RRB-
cord-347298-7kqrl3rv	872	35	.	.	.
cord-347298-7kqrl3rv	873	1	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	873	2	cells	cell	NNS
cord-347298-7kqrl3rv	873	3	and	and	CC
cord-347298-7kqrl3rv	873	4	germ	germ	NN
cord-347298-7kqrl3rv	873	5	cells	cell	NNS
cord-347298-7kqrl3rv	873	6	interact	interact	VBP
cord-347298-7kqrl3rv	873	7	through	through	IN
cord-347298-7kqrl3rv	873	8	production	production	NN
cord-347298-7kqrl3rv	873	9	of	of	IN
cord-347298-7kqrl3rv	873	10	various	various	JJ
cord-347298-7kqrl3rv	873	11	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	873	12	mediators	mediator	NNS
cord-347298-7kqrl3rv	873	13	,	,	,
cord-347298-7kqrl3rv	873	14	including	include	VBG
cord-347298-7kqrl3rv	873	15	interleukin	interleukin	NN
cord-347298-7kqrl3rv	873	16	(	(	-LRB-
cord-347298-7kqrl3rv	873	17	IL	IL	NNP
cord-347298-7kqrl3rv	873	18	)	)	-RRB-
cord-347298-7kqrl3rv	873	19	1	1	CD
cord-347298-7kqrl3rv	873	20	,	,	,
cord-347298-7kqrl3rv	873	21	IL6	IL6	NNP
cord-347298-7kqrl3rv	873	22	,	,	,
cord-347298-7kqrl3rv	873	23	activin	activin	NNP
cord-347298-7kqrl3rv	873	24	A	A	NNP
cord-347298-7kqrl3rv	873	25	,	,	,
cord-347298-7kqrl3rv	873	26	tumor	tumor	NN
cord-347298-7kqrl3rv	873	27	necrosis	necrosis	NN
cord-347298-7kqrl3rv	873	28	factor	factor	NN
cord-347298-7kqrl3rv	873	29	(	(	-LRB-
cord-347298-7kqrl3rv	873	30	TNF	TNF	NNP
cord-347298-7kqrl3rv	873	31	)	)	-RRB-
cord-347298-7kqrl3rv	873	32	,	,	,
cord-347298-7kqrl3rv	873	33	and	and	CC
cord-347298-7kqrl3rv	873	34	NO	no	UH
cord-347298-7kqrl3rv	873	35	,	,	,
cord-347298-7kqrl3rv	873	36	to	to	TO
cord-347298-7kqrl3rv	873	37	facilitate	facilitate	VB
cord-347298-7kqrl3rv	873	38	and	and	CC
cord-347298-7kqrl3rv	873	39	coordinate	coordinate	VB
cord-347298-7kqrl3rv	873	40	critical	critical	JJ
cord-347298-7kqrl3rv	873	41	events	event	NNS
cord-347298-7kqrl3rv	873	42	throughout	throughout	IN
cord-347298-7kqrl3rv	873	43	the	the	DT
cord-347298-7kqrl3rv	873	44	cycle	cycle	NN
cord-347298-7kqrl3rv	873	45	of	of	IN
cord-347298-7kqrl3rv	873	46	the	the	DT
cord-347298-7kqrl3rv	873	47	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	873	48	epithelium	epithelium	NN
cord-347298-7kqrl3rv	873	49	.	.	.
cord-347298-7kqrl3rv	874	1	The	the	DT
cord-347298-7kqrl3rv	874	2	development	development	NN
cord-347298-7kqrl3rv	874	3	and	and	CC
cord-347298-7kqrl3rv	874	4	activity	activity	NN
cord-347298-7kqrl3rv	874	5	of	of	IN
cord-347298-7kqrl3rv	874	6	the	the	DT
cord-347298-7kqrl3rv	874	7	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	874	8	cells	cell	NNS
cord-347298-7kqrl3rv	874	9	and	and	CC
cord-347298-7kqrl3rv	874	10	the	the	DT
cord-347298-7kqrl3rv	874	11	resident	resident	JJ
cord-347298-7kqrl3rv	874	12	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	874	13	involve	involve	VBP
cord-347298-7kqrl3rv	874	14	a	a	DT
cord-347298-7kqrl3rv	874	15	close	close	JJ
cord-347298-7kqrl3rv	874	16	mutual	mutual	JJ
cord-347298-7kqrl3rv	874	17	interaction	interaction	NN
cord-347298-7kqrl3rv	874	18	,	,	,
cord-347298-7kqrl3rv	874	19	mediated	mediate	VBN
cord-347298-7kqrl3rv	874	20	by	by	IN
cord-347298-7kqrl3rv	874	21	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	874	22	that	that	WDT
cord-347298-7kqrl3rv	874	23	remain	remain	VBP
cord-347298-7kqrl3rv	874	24	to	to	TO
cord-347298-7kqrl3rv	874	25	be	be	VB
cord-347298-7kqrl3rv	874	26	completely	completely	RB
cord-347298-7kqrl3rv	874	27	defined	define	VBN
cord-347298-7kqrl3rv	874	28	.	.	.
cord-347298-7kqrl3rv	875	1	The	the	DT
cord-347298-7kqrl3rv	875	2	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	875	3	cell	cell	NN
cord-347298-7kqrl3rv	875	4	and	and	CC
cord-347298-7kqrl3rv	875	5	the	the	DT
cord-347298-7kqrl3rv	875	6	resident	resident	NN
cord-347298-7kqrl3rv	875	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	875	8	,	,	,
cord-347298-7kqrl3rv	875	9	in	in	IN
cord-347298-7kqrl3rv	875	10	turn	turn	NN
cord-347298-7kqrl3rv	875	11	,	,	,
cord-347298-7kqrl3rv	875	12	influence	influence	VB
cord-347298-7kqrl3rv	875	13	the	the	DT
cord-347298-7kqrl3rv	875	14	activity	activity	NN
cord-347298-7kqrl3rv	875	15	of	of	IN
cord-347298-7kqrl3rv	875	16	the	the	DT
cord-347298-7kqrl3rv	875	17	antigen	antigen	NN
cord-347298-7kqrl3rv	875	18	-	-	HYPH
cord-347298-7kqrl3rv	875	19	presenting	present	VBG
cord-347298-7kqrl3rv	875	20	cells	cell	NNS
cord-347298-7kqrl3rv	875	21	(	(	-LRB-
cord-347298-7kqrl3rv	875	22	APC	APC	NNP
cord-347298-7kqrl3rv	875	23	;	;	:
cord-347298-7kqrl3rv	875	24	e.g.	e.g.	RB
cord-347298-7kqrl3rv	875	25	,	,	,
cord-347298-7kqrl3rv	875	26	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	875	27	cells	cell	NNS
cord-347298-7kqrl3rv	875	28	)	)	-RRB-
cord-347298-7kqrl3rv	875	29	and	and	CC
cord-347298-7kqrl3rv	875	30	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	875	31	within	within	IN
cord-347298-7kqrl3rv	875	32	the	the	DT
cord-347298-7kqrl3rv	875	33	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	875	34	tissue	tissue	NN
cord-347298-7kqrl3rv	875	35	to	to	TO
cord-347298-7kqrl3rv	875	36	control	control	VB
cord-347298-7kqrl3rv	875	37	local	local	JJ
cord-347298-7kqrl3rv	875	38	immune	immune	JJ
cord-347298-7kqrl3rv	875	39	events	event	NNS
cord-347298-7kqrl3rv	875	40	,	,	,
cord-347298-7kqrl3rv	875	41	such	such	JJ
cord-347298-7kqrl3rv	875	42	as	as	IN
cord-347298-7kqrl3rv	875	43	the	the	DT
cord-347298-7kqrl3rv	875	44	maintenance	maintenance	NN
cord-347298-7kqrl3rv	875	45	of	of	IN
cord-347298-7kqrl3rv	875	46	an	an	DT
cord-347298-7kqrl3rv	875	47	immunologically	immunologically	RB
cord-347298-7kqrl3rv	875	48	privileged	privileged	JJ
cord-347298-7kqrl3rv	875	49	environment	environment	NN
cord-347298-7kqrl3rv	875	50	.	.	.
cord-347298-7kqrl3rv	876	1	This	this	DT
cord-347298-7kqrl3rv	876	2	communication	communication	NN
cord-347298-7kqrl3rv	876	3	involves	involve	VBZ
cord-347298-7kqrl3rv	876	4	the	the	DT
cord-347298-7kqrl3rv	876	5	immunoregulatory	immunoregulatory	NNP
cord-347298-7kqrl3rv	876	6	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	876	7	transforming	transform	VBG
cord-347298-7kqrl3rv	876	8	growth	growth	NN
cord-347298-7kqrl3rv	876	9	factor	factor	NN
cord-347298-7kqrl3rv	876	10	(	(	-LRB-
cord-347298-7kqrl3rv	876	11	TGF	TGF	NNP
cord-347298-7kqrl3rv	876	12	)	)	-RRB-
cord-347298-7kqrl3rv	876	13	,	,	,
cord-347298-7kqrl3rv	876	14	activin	activin	NNP
cord-347298-7kqrl3rv	876	15	A	A	NNP
cord-347298-7kqrl3rv	876	16	,	,	,
cord-347298-7kqrl3rv	876	17	and	and	CC
cord-347298-7kqrl3rv	876	18	IL10	IL10	NNP
cord-347298-7kqrl3rv	876	19	,	,	,
cord-347298-7kqrl3rv	876	20	although	although	IN
cord-347298-7kqrl3rv	876	21	other	other	JJ
cord-347298-7kqrl3rv	876	22	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	876	23	may	may	MD
cord-347298-7kqrl3rv	876	24	also	also	RB
cord-347298-7kqrl3rv	876	25	be	be	VB
cord-347298-7kqrl3rv	876	26	involved	involve	VBN
cord-347298-7kqrl3rv	876	27	.	.	.
cord-347298-7kqrl3rv	877	1	male	male	JJ
cord-347298-7kqrl3rv	877	2	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	877	3	tract	tract	NN
cord-347298-7kqrl3rv	877	4	,	,	,
cord-347298-7kqrl3rv	877	5	disruption	disruption	NN
cord-347298-7kqrl3rv	877	6	of	of	IN
cord-347298-7kqrl3rv	877	7	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	877	8	and	and	CC
cord-347298-7kqrl3rv	877	9	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	877	10	during	during	IN
cord-347298-7kqrl3rv	877	11	systemic	systemic	JJ
cord-347298-7kqrl3rv	877	12	and	and	CC
cord-347298-7kqrl3rv	877	13	local	local	JJ
cord-347298-7kqrl3rv	877	14	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	877	15	events	event	NNS
cord-347298-7kqrl3rv	877	16	,	,	,
cord-347298-7kqrl3rv	877	17	and	and	CC
cord-347298-7kqrl3rv	877	18	the	the	DT
cord-347298-7kqrl3rv	877	19	response	response	NN
cord-347298-7kqrl3rv	877	20	to	to	IN
cord-347298-7kqrl3rv	877	21	vascular	vascular	JJ
cord-347298-7kqrl3rv	877	22	disturbances	disturbance	NNS
cord-347298-7kqrl3rv	877	23	.	.	.
cord-347298-7kqrl3rv	878	1	11.10.4.4.1	11.10.4.4.1	CD
cord-347298-7kqrl3rv	878	2	Normal	normal	JJ
cord-347298-7kqrl3rv	878	3	testicular	testicular	NN
cord-347298-7kqrl3rv	878	4	function	function	VB
cord-347298-7kqrl3rv	878	5	Direct	direct	JJ
cord-347298-7kqrl3rv	878	6	evidence	evidence	NN
cord-347298-7kqrl3rv	878	7	that	that	IN
cord-347298-7kqrl3rv	878	8	immune	immune	JJ
cord-347298-7kqrl3rv	878	9	privilege	privilege	NN
cord-347298-7kqrl3rv	878	10	is	be	VBZ
cord-347298-7kqrl3rv	878	11	due	due	JJ
cord-347298-7kqrl3rv	878	12	to	to	IN
cord-347298-7kqrl3rv	878	13	a	a	DT
cord-347298-7kqrl3rv	878	14	specialized	specialized	JJ
cord-347298-7kqrl3rv	878	15	immune	immune	JJ
cord-347298-7kqrl3rv	878	16	environment	environment	NN
cord-347298-7kqrl3rv	878	17	originally	originally	RB
cord-347298-7kqrl3rv	878	18	comes	come	VBZ
cord-347298-7kqrl3rv	878	19	from	from	IN
cord-347298-7kqrl3rv	878	20	studies	study	NNS
cord-347298-7kqrl3rv	878	21	involving	involve	VBG
cord-347298-7kqrl3rv	878	22	the	the	DT
cord-347298-7kqrl3rv	878	23	central	central	JJ
cord-347298-7kqrl3rv	878	24	nervous	nervous	JJ
cord-347298-7kqrl3rv	878	25	system	system	NN
cord-347298-7kqrl3rv	878	26	.	.	.
cord-347298-7kqrl3rv	879	1	Injection	injection	NN
cord-347298-7kqrl3rv	879	2	of	of	IN
cord-347298-7kqrl3rv	879	3	soluble	soluble	JJ
cord-347298-7kqrl3rv	879	4	antigen	antigen	NN
cord-347298-7kqrl3rv	879	5	into	into	IN
cord-347298-7kqrl3rv	879	6	the	the	DT
cord-347298-7kqrl3rv	879	7	compartments	compartment	NNS
cord-347298-7kqrl3rv	879	8	of	of	IN
cord-347298-7kqrl3rv	879	9	the	the	DT
cord-347298-7kqrl3rv	879	10	eye	eye	NN
cord-347298-7kqrl3rv	879	11	or	or	CC
cord-347298-7kqrl3rv	879	12	brain	brain	NN
cord-347298-7kqrl3rv	879	13	produces	produce	VBZ
cord-347298-7kqrl3rv	879	14	antigen	antigen	NN
cord-347298-7kqrl3rv	879	15	-	-	HYPH
cord-347298-7kqrl3rv	879	16	specific	specific	JJ
cord-347298-7kqrl3rv	879	17	suppression	suppression	NN
cord-347298-7kqrl3rv	879	18	of	of	IN
cord-347298-7kqrl3rv	879	19	cell	cell	NN
cord-347298-7kqrl3rv	879	20	-	-	HYPH
cord-347298-7kqrl3rv	879	21	mediated	mediate	VBN
cord-347298-7kqrl3rv	879	22	immunity	immunity	NN
cord-347298-7kqrl3rv	879	23	,	,	,
cord-347298-7kqrl3rv	879	24	specifically	specifically	RB
cord-347298-7kqrl3rv	879	25	type	type	NN
cord-347298-7kqrl3rv	879	26	1	1	CD
cord-347298-7kqrl3rv	879	27	reactions	reaction	NNS
cord-347298-7kqrl3rv	879	28	(	(	-LRB-
cord-347298-7kqrl3rv	879	29	Kaplan	Kaplan	NNP
cord-347298-7kqrl3rv	879	30	and	and	CC
cord-347298-7kqrl3rv	879	31	Streilein	Streilein	NNP
cord-347298-7kqrl3rv	879	32	1978	1978	CD
cord-347298-7kqrl3rv	879	33	;	;	:
cord-347298-7kqrl3rv	880	1	Wenkel	Wenkel	NNP
cord-347298-7kqrl3rv	880	2	et	et	NNP
cord-347298-7kqrl3rv	880	3	al	al	NNP
cord-347298-7kqrl3rv	880	4	.	.	.
cord-347298-7kqrl3rv	880	5	2000	2000	CD
cord-347298-7kqrl3rv	880	6	)	)	-RRB-
cord-347298-7kqrl3rv	880	7	.	.	.
cord-347298-7kqrl3rv	881	1	This	this	DT
cord-347298-7kqrl3rv	881	2	phenomenon	phenomenon	NN
cord-347298-7kqrl3rv	881	3	is	be	VBZ
cord-347298-7kqrl3rv	881	4	called	call	VBN
cord-347298-7kqrl3rv	881	5	acquired	acquire	VBN
cord-347298-7kqrl3rv	881	6	immune	immune	JJ
cord-347298-7kqrl3rv	881	7	deviation	deviation	NN
cord-347298-7kqrl3rv	881	8	(	(	-LRB-
cord-347298-7kqrl3rv	881	9	AID	aid	NN
cord-347298-7kqrl3rv	881	10	)	)	-RRB-
cord-347298-7kqrl3rv	881	11	,	,	,
cord-347298-7kqrl3rv	881	12	and	and	CC
cord-347298-7kqrl3rv	881	13	it	-PRON-	PRP
cord-347298-7kqrl3rv	881	14	is	be	VBZ
cord-347298-7kqrl3rv	881	15	possible	possible	JJ
cord-347298-7kqrl3rv	881	16	to	to	TO
cord-347298-7kqrl3rv	881	17	elicit	elicit	VB
cord-347298-7kqrl3rv	881	18	similar	similar	JJ
cord-347298-7kqrl3rv	881	19	inhibition	inhibition	NN
cord-347298-7kqrl3rv	881	20	of	of	IN
cord-347298-7kqrl3rv	881	21	antigen	antigen	NN
cord-347298-7kqrl3rv	881	22	-	-	HYPH
cord-347298-7kqrl3rv	881	23	specific	specific	JJ
cord-347298-7kqrl3rv	881	24	immune	immune	JJ
cord-347298-7kqrl3rv	881	25	responses	response	NNS
cord-347298-7kqrl3rv	881	26	by	by	IN
cord-347298-7kqrl3rv	881	27	prior	prior	JJ
cord-347298-7kqrl3rv	881	28	injection	injection	NN
cord-347298-7kqrl3rv	881	29	of	of	IN
cord-347298-7kqrl3rv	881	30	antigens	antigen	NNS
cord-347298-7kqrl3rv	881	31	into	into	IN
cord-347298-7kqrl3rv	881	32	the	the	DT
cord-347298-7kqrl3rv	881	33	testis	testis	NN
cord-347298-7kqrl3rv	881	34	(	(	-LRB-
cord-347298-7kqrl3rv	881	35	Ditzian	Ditzian	NNP
cord-347298-7kqrl3rv	881	36	-	-	HYPH
cord-347298-7kqrl3rv	881	37	Kadanoff	Kadanoff	NNP
cord-347298-7kqrl3rv	881	38	1999	1999	CD
cord-347298-7kqrl3rv	881	39	;	;	:
cord-347298-7kqrl3rv	881	40	Li	Li	NNP
cord-347298-7kqrl3rv	881	41	et	et	NNP
cord-347298-7kqrl3rv	881	42	al	al	NNP
cord-347298-7kqrl3rv	881	43	.	.	.
cord-347298-7kqrl3rv	882	1	1997	1997	CD
cord-347298-7kqrl3rv	882	2	;	;	:
cord-347298-7kqrl3rv	882	3	Veräjänkorva	Veräjänkorva	NNP
cord-347298-7kqrl3rv	882	4	et	et	FW
cord-347298-7kqrl3rv	882	5	al	al	NNP
cord-347298-7kqrl3rv	882	6	.	.	.
cord-347298-7kqrl3rv	882	7	2002	2002	CD
cord-347298-7kqrl3rv	882	8	)	)	-RRB-
cord-347298-7kqrl3rv	882	9	.	.	.
cord-347298-7kqrl3rv	883	1	The	the	DT
cord-347298-7kqrl3rv	883	2	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	883	3	cell	cell	NN
cord-347298-7kqrl3rv	883	4	and	and	CC
cord-347298-7kqrl3rv	883	5	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	883	6	cell	cell	NN
cord-347298-7kqrl3rv	883	7	are	be	VBP
cord-347298-7kqrl3rv	883	8	almost	almost	RB
cord-347298-7kqrl3rv	883	9	certainly	certainly	RB
cord-347298-7kqrl3rv	883	10	central	central	JJ
cord-347298-7kqrl3rv	883	11	to	to	IN
cord-347298-7kqrl3rv	883	12	this	this	DT
cord-347298-7kqrl3rv	883	13	process	process	NN
cord-347298-7kqrl3rv	883	14	,	,	,
cord-347298-7kqrl3rv	883	15	although	although	IN
cord-347298-7kqrl3rv	883	16	contributions	contribution	NNS
cord-347298-7kqrl3rv	883	17	from	from	IN
cord-347298-7kqrl3rv	883	18	other	other	JJ
cord-347298-7kqrl3rv	883	19	testicular	testicular	JJ
cord-347298-7kqrl3rv	883	20	cells	cell	NNS
cord-347298-7kqrl3rv	883	21	are	be	VBP
cord-347298-7kqrl3rv	883	22	to	to	TO
cord-347298-7kqrl3rv	883	23	be	be	VB
cord-347298-7kqrl3rv	883	24	expected	expect	VBN
cord-347298-7kqrl3rv	883	25	.	.	.
cord-347298-7kqrl3rv	884	1	The	the	DT
cord-347298-7kqrl3rv	884	2	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	884	3	responsible	responsible	JJ
cord-347298-7kqrl3rv	884	4	presumably	presumably	RB
cord-347298-7kqrl3rv	884	5	involve	involve	VBP
cord-347298-7kqrl3rv	884	6	the	the	DT
cord-347298-7kqrl3rv	884	7	recruitment	recruitment	NN
cord-347298-7kqrl3rv	884	8	and	and	CC
cord-347298-7kqrl3rv	884	9	functional	functional	JJ
cord-347298-7kqrl3rv	884	10	deviation	deviation	NN
cord-347298-7kqrl3rv	884	11	of	of	IN
cord-347298-7kqrl3rv	884	12	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	884	13	(	(	-LRB-
cord-347298-7kqrl3rv	884	14	and	and	CC
cord-347298-7kqrl3rv	884	15	possibly	possibly	RB
cord-347298-7kqrl3rv	884	16	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	884	17	cells	cell	NNS
cord-347298-7kqrl3rv	884	18	)	)	-RRB-
cord-347298-7kqrl3rv	884	19	within	within	IN
cord-347298-7kqrl3rv	884	20	the	the	DT
cord-347298-7kqrl3rv	884	21	testis	testis	NN
cord-347298-7kqrl3rv	884	22	(	(	-LRB-
cord-347298-7kqrl3rv	884	23	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	884	24	2002	2002	CD
cord-347298-7kqrl3rv	884	25	)	)	-RRB-
cord-347298-7kqrl3rv	884	26	,	,	,
cord-347298-7kqrl3rv	884	27	the	the	DT
cord-347298-7kqrl3rv	884	28	subsequent	subsequent	JJ
cord-347298-7kqrl3rv	884	29	recruitment	recruitment	NN
cord-347298-7kqrl3rv	884	30	of	of	IN
cord-347298-7kqrl3rv	884	31	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	884	32	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	884	33	subsets	subset	NNS
cord-347298-7kqrl3rv	884	34	(	(	-LRB-
cord-347298-7kqrl3rv	884	35	Tompkins	Tompkins	NNP
cord-347298-7kqrl3rv	884	36	et	et	NNP
cord-347298-7kqrl3rv	884	37	al	al	NNP
cord-347298-7kqrl3rv	884	38	.	.	NNP
cord-347298-7kqrl3rv	884	39	1998	1998	CD
cord-347298-7kqrl3rv	884	40	)	)	-RRB-
cord-347298-7kqrl3rv	884	41	,	,	,
cord-347298-7kqrl3rv	884	42	the	the	DT
cord-347298-7kqrl3rv	884	43	production	production	NN
cord-347298-7kqrl3rv	884	44	of	of	IN
cord-347298-7kqrl3rv	884	45	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	884	46	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	884	47	,	,	,
cord-347298-7kqrl3rv	884	48	such	such	JJ
cord-347298-7kqrl3rv	884	49	as	as	IN
cord-347298-7kqrl3rv	884	50	TGF	TGF	NNP
cord-347298-7kqrl3rv	884	51	family	family	NN
cord-347298-7kqrl3rv	884	52	members	member	NNS
cord-347298-7kqrl3rv	884	53	and	and	CC
cord-347298-7kqrl3rv	884	54	IL10	IL10	NNP
cord-347298-7kqrl3rv	884	55	(	(	-LRB-
cord-347298-7kqrl3rv	884	56	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	884	57	et	et	NNP
cord-347298-7kqrl3rv	884	58	al	al	NNP
cord-347298-7kqrl3rv	884	59	.	.	NNP
cord-347298-7kqrl3rv	884	60	2005	2005	CD
cord-347298-7kqrl3rv	884	61	;	;	:
cord-347298-7kqrl3rv	884	62	Suarez	Suarez	NNP
cord-347298-7kqrl3rv	884	63	-	-	HYPH
cord-347298-7kqrl3rv	884	64	Pinzon	Pinzon	NNP
cord-347298-7kqrl3rv	884	65	et	et	NNP
cord-347298-7kqrl3rv	884	66	al	al	NNP
cord-347298-7kqrl3rv	884	67	.	.	.
cord-347298-7kqrl3rv	884	68	2000	2000	CD
cord-347298-7kqrl3rv	884	69	)	)	-RRB-
cord-347298-7kqrl3rv	884	70	,	,	,
cord-347298-7kqrl3rv	884	71	local	local	JJ
cord-347298-7kqrl3rv	884	72	high	high	JJ
cord-347298-7kqrl3rv	884	73	concentrations	concentration	NNS
cord-347298-7kqrl3rv	884	74	of	of	IN
cord-347298-7kqrl3rv	884	75	androgenic	androgenic	JJ
cord-347298-7kqrl3rv	884	76	steroids	steroid	NNS
cord-347298-7kqrl3rv	884	77	,	,	,
cord-347298-7kqrl3rv	884	78	prostanoids	prostanoid	NNS
cord-347298-7kqrl3rv	884	79	,	,	,
cord-347298-7kqrl3rv	884	80	and	and	CC
cord-347298-7kqrl3rv	884	81	other	other	JJ
cord-347298-7kqrl3rv	884	82	bioactive	bioactive	JJ
cord-347298-7kqrl3rv	884	83	lipids	lipid	NNS
cord-347298-7kqrl3rv	884	84	(	(	-LRB-
cord-347298-7kqrl3rv	884	85	Foulds	Foulds	NNP
cord-347298-7kqrl3rv	884	86	et	et	NNP
cord-347298-7kqrl3rv	884	87	al	al	NNP
cord-347298-7kqrl3rv	884	88	.	.	NNP
cord-347298-7kqrl3rv	884	89	2008	2008	CD
cord-347298-7kqrl3rv	884	90	;	;	:
cord-347298-7kqrl3rv	884	91	Winnall	Winnall	NNP
cord-347298-7kqrl3rv	884	92	et	et	NNP
cord-347298-7kqrl3rv	884	93	al	al	NNP
cord-347298-7kqrl3rv	884	94	.	.	NNP
cord-347298-7kqrl3rv	884	95	2007	2007	CD
cord-347298-7kqrl3rv	884	96	)	)	-RRB-
cord-347298-7kqrl3rv	884	97	,	,	,
cord-347298-7kqrl3rv	884	98	complement	complement	VBP
cord-347298-7kqrl3rv	884	99	inhibitors	inhibitor	NNS
cord-347298-7kqrl3rv	884	100	Mizuno	Mizuno	NNP
cord-347298-7kqrl3rv	884	101	et	et	NNP
cord-347298-7kqrl3rv	884	102	al	al	NNP
cord-347298-7kqrl3rv	884	103	.	.	.
cord-347298-7kqrl3rv	884	104	2006	2006	CD
cord-347298-7kqrl3rv	884	105	)	)	-RRB-
cord-347298-7kqrl3rv	884	106	,	,	,
cord-347298-7kqrl3rv	884	107	and	and	CC
cord-347298-7kqrl3rv	884	108	testicular	testicular	JJ
cord-347298-7kqrl3rv	884	109	expression	expression	NN
cord-347298-7kqrl3rv	884	110	of	of	IN
cord-347298-7kqrl3rv	884	111	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	884	112	MHC	MHC	NNP
cord-347298-7kqrl3rv	884	113	and	and	CC
cord-347298-7kqrl3rv	884	114	costimulatory	costimulatory	NNP
cord-347298-7kqrl3rv	884	115	molecules	molecule	NNS
cord-347298-7kqrl3rv	885	1	(	(	-LRB-
cord-347298-7kqrl3rv	885	2	Dal	Dal	NNP
cord-347298-7kqrl3rv	885	3	Secco	Secco	NNP
cord-347298-7kqrl3rv	885	4	et	et	FW
cord-347298-7kqrl3rv	885	5	al	al	NNP
cord-347298-7kqrl3rv	885	6	.	.	.
cord-347298-7kqrl3rv	886	1	2008	2008	CD
cord-347298-7kqrl3rv	886	2	;	;	:
cord-347298-7kqrl3rv	886	3	Fiszer	Fiszer	NNP
cord-347298-7kqrl3rv	886	4	et	et	NNP
cord-347298-7kqrl3rv	886	5	al	al	NNP
cord-347298-7kqrl3rv	886	6	.	.	.
cord-347298-7kqrl3rv	887	1	1997	1997	CD
cord-347298-7kqrl3rv	887	2	;	;	:
cord-347298-7kqrl3rv	887	3	Ryan	Ryan	NNP
cord-347298-7kqrl3rv	887	4	et	et	NNP
cord-347298-7kqrl3rv	887	5	al	al	NNP
cord-347298-7kqrl3rv	887	6	.	.	.
cord-347298-7kqrl3rv	887	7	2002	2002	CD
cord-347298-7kqrl3rv	887	8	)	)	-RRB-
cord-347298-7kqrl3rv	887	9	.	.	.
cord-347298-7kqrl3rv	888	1	Macrophages	macrophage	NNS
cord-347298-7kqrl3rv	888	2	play	play	VBP
cord-347298-7kqrl3rv	888	3	an	an	DT
cord-347298-7kqrl3rv	888	4	important	important	JJ
cord-347298-7kqrl3rv	888	5	role	role	NN
cord-347298-7kqrl3rv	888	6	in	in	IN
cord-347298-7kqrl3rv	888	7	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	888	8	cell	cell	NN
cord-347298-7kqrl3rv	888	9	development	development	NN
cord-347298-7kqrl3rv	888	10	and	and	CC
cord-347298-7kqrl3rv	888	11	function	function	NN
cord-347298-7kqrl3rv	888	12	.	.	.
cord-347298-7kqrl3rv	889	1	There	there	EX
cord-347298-7kqrl3rv	889	2	is	be	VBZ
cord-347298-7kqrl3rv	889	3	a	a	DT
cord-347298-7kqrl3rv	889	4	close	close	JJ
cord-347298-7kqrl3rv	889	5	temporal	temporal	JJ
cord-347298-7kqrl3rv	889	6	link	link	NN
cord-347298-7kqrl3rv	889	7	between	between	IN
cord-347298-7kqrl3rv	889	8	the	the	DT
cord-347298-7kqrl3rv	889	9	maturation	maturation	NN
cord-347298-7kqrl3rv	889	10	of	of	IN
cord-347298-7kqrl3rv	889	11	the	the	DT
cord-347298-7kqrl3rv	889	12	adult	adult	NN
cord-347298-7kqrl3rv	889	13	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	889	14	cell	cell	NN
cord-347298-7kqrl3rv	889	15	population	population	NN
cord-347298-7kqrl3rv	889	16	and	and	CC
cord-347298-7kqrl3rv	889	17	the	the	DT
cord-347298-7kqrl3rv	889	18	increase	increase	NN
cord-347298-7kqrl3rv	889	19	in	in	IN
cord-347298-7kqrl3rv	889	20	the	the	DT
cord-347298-7kqrl3rv	889	21	number	number	NN
cord-347298-7kqrl3rv	889	22	of	of	IN
cord-347298-7kqrl3rv	889	23	testicular	testicular	JJ
cord-347298-7kqrl3rv	889	24	resident	resident	NN
cord-347298-7kqrl3rv	889	25	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	889	26	during	during	IN
cord-347298-7kqrl3rv	889	27	puberty	puberty	NN
cord-347298-7kqrl3rv	889	28	(	(	-LRB-
cord-347298-7kqrl3rv	889	29	Hardy	Hardy	NNP
cord-347298-7kqrl3rv	889	30	et	et	FW
cord-347298-7kqrl3rv	889	31	al	al	NNP
cord-347298-7kqrl3rv	889	32	.	.	.
cord-347298-7kqrl3rv	890	1	1989	1989	CD
cord-347298-7kqrl3rv	890	2	;	;	:
cord-347298-7kqrl3rv	890	3	Raburn	Raburn	NNP
cord-347298-7kqrl3rv	890	4	et	et	NNP
cord-347298-7kqrl3rv	890	5	al	al	NNP
cord-347298-7kqrl3rv	890	6	.	.	NNP
cord-347298-7kqrl3rv	890	7	1993	1993	CD
cord-347298-7kqrl3rv	890	8	;	;	:
cord-347298-7kqrl3rv	890	9	Vergouwen	Vergouwen	NNP
cord-347298-7kqrl3rv	890	10	et	et	NNP
cord-347298-7kqrl3rv	890	11	al	al	NNP
cord-347298-7kqrl3rv	890	12	.	.	.
cord-347298-7kqrl3rv	890	13	1993	1993	CD
cord-347298-7kqrl3rv	890	14	)	)	-RRB-
cord-347298-7kqrl3rv	890	15	.	.	.
cord-347298-7kqrl3rv	891	1	Reductions	reduction	NNS
cord-347298-7kqrl3rv	891	2	in	in	IN
cord-347298-7kqrl3rv	891	3	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	891	4	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	891	5	due	due	IN
cord-347298-7kqrl3rv	891	6	to	to	IN
cord-347298-7kqrl3rv	891	7	specific	specific	JJ
cord-347298-7kqrl3rv	891	8	depletion	depletion	NN
cord-347298-7kqrl3rv	891	9	methods	method	NNS
cord-347298-7kqrl3rv	891	10	or	or	CC
cord-347298-7kqrl3rv	891	11	in	in	IN
cord-347298-7kqrl3rv	891	12	the	the	DT
cord-347298-7kqrl3rv	891	13	macrophage	macrophage	NN
cord-347298-7kqrl3rv	891	14	-	-	HYPH
cord-347298-7kqrl3rv	891	15	deficient	deficient	JJ
cord-347298-7kqrl3rv	891	16	(	(	-LRB-
cord-347298-7kqrl3rv	891	17	op	op	NN
cord-347298-7kqrl3rv	891	18	/	/	SYM
cord-347298-7kqrl3rv	891	19	op	op	NN
cord-347298-7kqrl3rv	891	20	)	)	-RRB-
cord-347298-7kqrl3rv	891	21	mouse	mouse	NN
cord-347298-7kqrl3rv	891	22	lead	lead	NN
cord-347298-7kqrl3rv	891	23	to	to	IN
cord-347298-7kqrl3rv	891	24	disorders	disorder	NNS
cord-347298-7kqrl3rv	891	25	of	of	IN
cord-347298-7kqrl3rv	891	26	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	891	27	cell	cell	NN
cord-347298-7kqrl3rv	891	28	development	development	NN
cord-347298-7kqrl3rv	891	29	and	and	CC
cord-347298-7kqrl3rv	891	30	mature	mature	JJ
cord-347298-7kqrl3rv	891	31	function	function	NN
cord-347298-7kqrl3rv	892	1	(	(	-LRB-
cord-347298-7kqrl3rv	892	2	Cohen	Cohen	NNP
cord-347298-7kqrl3rv	892	3	et	et	NNP
cord-347298-7kqrl3rv	892	4	al	al	NNP
cord-347298-7kqrl3rv	892	5	.	.	.
cord-347298-7kqrl3rv	893	1	1997	1997	CD
cord-347298-7kqrl3rv	893	2	;	;	:
cord-347298-7kqrl3rv	893	3	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	893	4	et	et	NNP
cord-347298-7kqrl3rv	893	5	al	al	NNP
cord-347298-7kqrl3rv	893	6	.	.	.
cord-347298-7kqrl3rv	894	1	1994a	1994a	CD
cord-347298-7kqrl3rv	894	2	,	,	,
cord-347298-7kqrl3rv	894	3	b	b	LS
cord-347298-7kqrl3rv	894	4	)	)	-RRB-
cord-347298-7kqrl3rv	894	5	,	,	,
cord-347298-7kqrl3rv	894	6	and	and	CC
cord-347298-7kqrl3rv	894	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	894	8	macrophage	macrophage	NN
cord-347298-7kqrl3rv	894	9	-	-	HYPH
cord-347298-7kqrl3rv	894	10	conditioned	condition	VBN
cord-347298-7kqrl3rv	894	11	medium	medium	NN
cord-347298-7kqrl3rv	894	12	stimulates	stimulate	VBZ
cord-347298-7kqrl3rv	894	13	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	894	14	cell	cell	NN
cord-347298-7kqrl3rv	894	15	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	894	16	under	under	IN
cord-347298-7kqrl3rv	894	17	certain	certain	JJ
cord-347298-7kqrl3rv	894	18	conditions	condition	NNS
cord-347298-7kqrl3rv	894	19	(	(	-LRB-
cord-347298-7kqrl3rv	894	20	Nes	Nes	NNP
cord-347298-7kqrl3rv	894	21	et	et	NNP
cord-347298-7kqrl3rv	894	22	al	al	NNP
cord-347298-7kqrl3rv	894	23	.	.	.
cord-347298-7kqrl3rv	895	1	2000	2000	CD
cord-347298-7kqrl3rv	895	2	;	;	:
cord-347298-7kqrl3rv	895	3	Yee	Yee	NNP
cord-347298-7kqrl3rv	895	4	and	and	CC
cord-347298-7kqrl3rv	895	5	Hutson	Hutson	NNP
cord-347298-7kqrl3rv	895	6	1985	1985	CD
cord-347298-7kqrl3rv	895	7	)	)	-RRB-
cord-347298-7kqrl3rv	895	8	.	.	.
cord-347298-7kqrl3rv	896	1	These	these	DT
cord-347298-7kqrl3rv	896	2	supportive	supportive	JJ
cord-347298-7kqrl3rv	896	3	functions	function	NNS
cord-347298-7kqrl3rv	896	4	of	of	IN
cord-347298-7kqrl3rv	896	5	the	the	DT
cord-347298-7kqrl3rv	896	6	testicular	testicular	JJ
cord-347298-7kqrl3rv	896	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	896	8	may	may	MD
cord-347298-7kqrl3rv	896	9	involve	involve	VB
cord-347298-7kqrl3rv	896	10	production	production	NN
cord-347298-7kqrl3rv	896	11	of	of	IN
cord-347298-7kqrl3rv	896	12	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	896	13	and	and	CC
cord-347298-7kqrl3rv	896	14	other	other	JJ
cord-347298-7kqrl3rv	896	15	secreted	secrete	VBN
cord-347298-7kqrl3rv	896	16	mediators	mediator	NNS
cord-347298-7kqrl3rv	896	17	(	(	-LRB-
cord-347298-7kqrl3rv	896	18	Khan	Khan	NNP
cord-347298-7kqrl3rv	896	19	et	et	NNP
cord-347298-7kqrl3rv	896	20	al	al	NNP
cord-347298-7kqrl3rv	896	21	.	.	.
cord-347298-7kqrl3rv	897	1	1992b	1992b	CD
cord-347298-7kqrl3rv	898	1	;	;	:
cord-347298-7kqrl3rv	898	2	Warren	Warren	NNP
cord-347298-7kqrl3rv	898	3	et	et	NNP
cord-347298-7kqrl3rv	898	4	al	al	NNP
cord-347298-7kqrl3rv	898	5	.	.	NNP
cord-347298-7kqrl3rv	898	6	1990	1990	CD
cord-347298-7kqrl3rv	898	7	)	)	-RRB-
cord-347298-7kqrl3rv	898	8	,	,	,
cord-347298-7kqrl3rv	898	9	as	as	RB
cord-347298-7kqrl3rv	898	10	well	well	RB
cord-347298-7kqrl3rv	898	11	as	as	IN
cord-347298-7kqrl3rv	898	12	the	the	DT
cord-347298-7kqrl3rv	898	13	distinctive	distinctive	JJ
cord-347298-7kqrl3rv	898	14	intercytoplasmic	intercytoplasmic	JJ
cord-347298-7kqrl3rv	898	15	specializations	specialization	NNS
cord-347298-7kqrl3rv	898	16	that	that	WDT
cord-347298-7kqrl3rv	898	17	develop	develop	VBP
cord-347298-7kqrl3rv	898	18	between	between	IN
cord-347298-7kqrl3rv	898	19	the	the	DT
cord-347298-7kqrl3rv	898	20	two	two	CD
cord-347298-7kqrl3rv	898	21	cell	cell	NN
cord-347298-7kqrl3rv	898	22	types	type	NNS
cord-347298-7kqrl3rv	898	23	(	(	-LRB-
cord-347298-7kqrl3rv	898	24	Hutson	Hutson	NNP
cord-347298-7kqrl3rv	898	25	1992	1992	CD
cord-347298-7kqrl3rv	898	26	;	;	:
cord-347298-7kqrl3rv	898	27	Miller	Miller	NNP
cord-347298-7kqrl3rv	898	28	et	et	NNP
cord-347298-7kqrl3rv	898	29	al	al	NNP
cord-347298-7kqrl3rv	898	30	.	.	.
cord-347298-7kqrl3rv	898	31	1983	1983	CD
cord-347298-7kqrl3rv	898	32	)	)	-RRB-
cord-347298-7kqrl3rv	898	33	.	.	.
cord-347298-7kqrl3rv	899	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	899	2	has	have	VBZ
cord-347298-7kqrl3rv	899	3	also	also	RB
cord-347298-7kqrl3rv	899	4	been	be	VBN
cord-347298-7kqrl3rv	899	5	shown	show	VBN
cord-347298-7kqrl3rv	899	6	that	that	IN
cord-347298-7kqrl3rv	899	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	899	8	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	899	9	support	support	VBP
cord-347298-7kqrl3rv	899	10	basal	basal	NN
cord-347298-7kqrl3rv	899	11	steroidogenesis	steroidogenesis	NN
cord-347298-7kqrl3rv	899	12	in	in	IN
cord-347298-7kqrl3rv	899	13	the	the	DT
cord-347298-7kqrl3rv	899	14	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	899	15	cells	cell	NNS
cord-347298-7kqrl3rv	899	16	by	by	IN
cord-347298-7kqrl3rv	899	17	providing	provide	VBG
cord-347298-7kqrl3rv	899	18	25-hydroxycholesterol	25-hydroxycholesterol	CD
cord-347298-7kqrl3rv	899	19	as	as	IN
cord-347298-7kqrl3rv	899	20	a	a	DT
cord-347298-7kqrl3rv	899	21	substrate	substrate	NN
cord-347298-7kqrl3rv	899	22	for	for	IN
cord-347298-7kqrl3rv	899	23	testosterone	testosterone	NN
cord-347298-7kqrl3rv	899	24	biosynthesis	biosynthesis	NN
cord-347298-7kqrl3rv	899	25	(	(	-LRB-
cord-347298-7kqrl3rv	899	26	Nes	Nes	NNP
cord-347298-7kqrl3rv	899	27	et	et	NNP
cord-347298-7kqrl3rv	899	28	al	al	NNP
cord-347298-7kqrl3rv	899	29	.	.	.
cord-347298-7kqrl3rv	899	30	2000	2000	CD
cord-347298-7kqrl3rv	899	31	)	)	-RRB-
cord-347298-7kqrl3rv	899	32	.	.	.
cord-347298-7kqrl3rv	900	1	Endogenous	endogenous	JJ
cord-347298-7kqrl3rv	900	2	regulation	regulation	NN
cord-347298-7kqrl3rv	900	3	of	of	IN
cord-347298-7kqrl3rv	900	4	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	900	5	pathways	pathway	NNS
cord-347298-7kqrl3rv	900	6	within	within	IN
cord-347298-7kqrl3rv	900	7	the	the	DT
cord-347298-7kqrl3rv	900	8	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	900	9	epithelium	epithelium	NN
cord-347298-7kqrl3rv	900	10	appears	appear	VBZ
cord-347298-7kqrl3rv	900	11	to	to	TO
cord-347298-7kqrl3rv	900	12	be	be	VB
cord-347298-7kqrl3rv	900	13	involved	involve	VBN
cord-347298-7kqrl3rv	900	14	in	in	IN
cord-347298-7kqrl3rv	900	15	the	the	DT
cord-347298-7kqrl3rv	900	16	fine	fine	JJ
cord-347298-7kqrl3rv	900	17	control	control	NN
cord-347298-7kqrl3rv	900	18	of	of	IN
cord-347298-7kqrl3rv	900	19	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	900	20	.	.	.
cord-347298-7kqrl3rv	901	1	Studies	study	NNS
cord-347298-7kqrl3rv	901	2	in	in	IN
cord-347298-7kqrl3rv	901	3	the	the	DT
cord-347298-7kqrl3rv	901	4	rat	rat	NN
cord-347298-7kqrl3rv	901	5	and	and	CC
cord-347298-7kqrl3rv	901	6	mouse	mouse	NN
cord-347298-7kqrl3rv	901	7	indicate	indicate	VBP
cord-347298-7kqrl3rv	901	8	that	that	IN
cord-347298-7kqrl3rv	901	9	nuclear	nuclear	JJ
cord-347298-7kqrl3rv	901	10	localization	localization	NN
cord-347298-7kqrl3rv	901	11	(	(	-LRB-
cord-347298-7kqrl3rv	901	12	i.e.	i.e.	FW
cord-347298-7kqrl3rv	901	13	,	,	,
cord-347298-7kqrl3rv	901	14	activation	activation	NN
cord-347298-7kqrl3rv	901	15	)	)	-RRB-
cord-347298-7kqrl3rv	901	16	of	of	IN
cord-347298-7kqrl3rv	901	17	the	the	DT
cord-347298-7kqrl3rv	901	18	key	key	JJ
cord-347298-7kqrl3rv	901	19	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	901	20	transcription	transcription	NN
cord-347298-7kqrl3rv	901	21	factor	factor	NN
cord-347298-7kqrl3rv	901	22	NFB	NFB	NNP
cord-347298-7kqrl3rv	901	23	,	,	,
cord-347298-7kqrl3rv	901	24	and	and	CC
cord-347298-7kqrl3rv	901	25	expression	expression	NN
cord-347298-7kqrl3rv	901	26	of	of	IN
cord-347298-7kqrl3rv	901	27	the	the	DT
cord-347298-7kqrl3rv	901	28	inflammation	inflammation	NN
cord-347298-7kqrl3rv	901	29	-	-	HYPH
cord-347298-7kqrl3rv	901	30	responsive	responsive	JJ
cord-347298-7kqrl3rv	901	31	genes	gene	NNS
cord-347298-7kqrl3rv	901	32	,	,	,
cord-347298-7kqrl3rv	901	33	IL1	IL1	NNP
cord-347298-7kqrl3rv	901	34	,	,	,
cord-347298-7kqrl3rv	901	35	TNF	TNF	NNP
cord-347298-7kqrl3rv	901	36	,	,	,
cord-347298-7kqrl3rv	901	37	IL6	IL6	NNP
cord-347298-7kqrl3rv	901	38	,	,	,
cord-347298-7kqrl3rv	901	39	activin	activin	NNP
cord-347298-7kqrl3rv	901	40	A	A	NNP
cord-347298-7kqrl3rv	901	41	,	,	,
cord-347298-7kqrl3rv	901	42	and	and	CC
cord-347298-7kqrl3rv	901	43	iNOS	inos	RB
cord-347298-7kqrl3rv	901	44	,	,	,
cord-347298-7kqrl3rv	901	45	in	in	IN
cord-347298-7kqrl3rv	901	46	the	the	DT
cord-347298-7kqrl3rv	901	47	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	901	48	cell	cell	NN
cord-347298-7kqrl3rv	901	49	and	and	CC
cord-347298-7kqrl3rv	901	50	the	the	DT
cord-347298-7kqrl3rv	901	51	germ	germ	NN
cord-347298-7kqrl3rv	901	52	cells	cell	NNS
cord-347298-7kqrl3rv	901	53	describe	describe	VBP
cord-347298-7kqrl3rv	901	54	cyclical	cyclical	JJ
cord-347298-7kqrl3rv	901	55	patterns	pattern	NNS
cord-347298-7kqrl3rv	901	56	within	within	IN
cord-347298-7kqrl3rv	901	57	the	the	DT
cord-347298-7kqrl3rv	901	58	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	901	59	epithelium	epithelium	NN
cord-347298-7kqrl3rv	901	60	that	that	WDT
cord-347298-7kqrl3rv	901	61	coincide	coincide	VBP
cord-347298-7kqrl3rv	901	62	with	with	IN
cord-347298-7kqrl3rv	901	63	critical	critical	JJ
cord-347298-7kqrl3rv	901	64	events	event	NNS
cord-347298-7kqrl3rv	901	65	in	in	IN
cord-347298-7kqrl3rv	901	66	the	the	DT
cord-347298-7kqrl3rv	901	67	cycle	cycle	NN
cord-347298-7kqrl3rv	901	68	of	of	IN
cord-347298-7kqrl3rv	901	69	the	the	DT
cord-347298-7kqrl3rv	901	70	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	901	71	epithelium	epithelium	NN
cord-347298-7kqrl3rv	901	72	(	(	-LRB-
cord-347298-7kqrl3rv	901	73	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	901	74	and	and	CC
cord-347298-7kqrl3rv	901	75	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	901	76	2008	2008	CD
cord-347298-7kqrl3rv	901	77	)	)	-RRB-
cord-347298-7kqrl3rv	901	78	.	.	.
cord-347298-7kqrl3rv	902	1	Most	most	RBS
cord-347298-7kqrl3rv	902	2	notably	notably	RB
cord-347298-7kqrl3rv	902	3	,	,	,
cord-347298-7kqrl3rv	902	4	release	release	NN
cord-347298-7kqrl3rv	902	5	of	of	IN
cord-347298-7kqrl3rv	902	6	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	902	7	from	from	IN
cord-347298-7kqrl3rv	902	8	the	the	DT
cord-347298-7kqrl3rv	902	9	epithelium	epithelium	NN
cord-347298-7kqrl3rv	902	10	(	(	-LRB-
cord-347298-7kqrl3rv	902	11	spermiation	spermiation	NN
cord-347298-7kqrl3rv	902	12	)	)	-RRB-
cord-347298-7kqrl3rv	902	13	in	in	IN
cord-347298-7kqrl3rv	902	14	the	the	DT
cord-347298-7kqrl3rv	902	15	rat	rat	NN
cord-347298-7kqrl3rv	902	16	testis	testis	NN
cord-347298-7kqrl3rv	902	17	is	be	VBZ
cord-347298-7kqrl3rv	902	18	followed	follow	VBN
cord-347298-7kqrl3rv	902	19	by	by	IN
cord-347298-7kqrl3rv	902	20	an	an	DT
cord-347298-7kqrl3rv	902	21	increase	increase	NN
cord-347298-7kqrl3rv	902	22	in	in	IN
cord-347298-7kqrl3rv	902	23	the	the	DT
cord-347298-7kqrl3rv	902	24	production	production	NN
cord-347298-7kqrl3rv	902	25	of	of	IN
cord-347298-7kqrl3rv	902	26	IL1	IL1	NNP
cord-347298-7kqrl3rv	902	27	,	,	,
cord-347298-7kqrl3rv	902	28	IL6	IL6	NNP
cord-347298-7kqrl3rv	902	29	,	,	,
cord-347298-7kqrl3rv	902	30	and	and	CC
cord-347298-7kqrl3rv	902	31	activin	activin	NNP
cord-347298-7kqrl3rv	902	32	A	a	NN
cord-347298-7kqrl3rv	902	33	by	by	IN
cord-347298-7kqrl3rv	902	34	the	the	DT
cord-347298-7kqrl3rv	902	35	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	902	36	cells	cell	NNS
cord-347298-7kqrl3rv	902	37	and	and	CC
cord-347298-7kqrl3rv	902	38	of	of	IN
cord-347298-7kqrl3rv	902	39	TNF	TNF	NNP
cord-347298-7kqrl3rv	902	40	and	and	CC
cord-347298-7kqrl3rv	902	41	iNOS	inos	XX
cord-347298-7kqrl3rv	902	42	by	by	IN
cord-347298-7kqrl3rv	902	43	the	the	DT
cord-347298-7kqrl3rv	902	44	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	902	45	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	902	46	et	et	NNP
cord-347298-7kqrl3rv	902	47	al	al	NNP
cord-347298-7kqrl3rv	902	48	.	.	NNP
cord-347298-7kqrl3rv	902	49	1995	1995	CD
cord-347298-7kqrl3rv	902	50	;	;	:
cord-347298-7kqrl3rv	902	51	Kaipia	Kaipia	NNP
cord-347298-7kqrl3rv	902	52	et	et	NNP
cord-347298-7kqrl3rv	902	53	al	al	NNP
cord-347298-7kqrl3rv	902	54	.	.	.
cord-347298-7kqrl3rv	902	55	1992	1992	CD
cord-347298-7kqrl3rv	902	56	;	;	.
cord-347298-7kqrl3rv	903	1	Söder	Söder	NNP
cord-347298-7kqrl3rv	903	2	et	et	NNP
cord-347298-7kqrl3rv	903	3	al	al	NNP
cord-347298-7kqrl3rv	903	4	.	.	.
cord-347298-7kqrl3rv	904	1	1991	1991	CD
cord-347298-7kqrl3rv	904	2	;	;	:
cord-347298-7kqrl3rv	904	3	Syed	Syed	NNP
cord-347298-7kqrl3rv	904	4	et	et	NNP
cord-347298-7kqrl3rv	904	5	al	al	NNP
cord-347298-7kqrl3rv	904	6	.	.	.
cord-347298-7kqrl3rv	905	1	1993	1993	CD
cord-347298-7kqrl3rv	905	2	;	;	:
cord-347298-7kqrl3rv	905	3	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	905	4	et	et	NNP
cord-347298-7kqrl3rv	905	5	al	al	NNP
cord-347298-7kqrl3rv	905	6	.	.	.
cord-347298-7kqrl3rv	906	1	2000a	2000a	CD
cord-347298-7kqrl3rv	907	1	;	;	:
cord-347298-7kqrl3rv	907	2	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	907	3	et	et	NNP
cord-347298-7kqrl3rv	907	4	al	al	NNP
cord-347298-7kqrl3rv	907	5	.	.	.
cord-347298-7kqrl3rv	907	6	2006	2006	CD
cord-347298-7kqrl3rv	907	7	)	)	-RRB-
cord-347298-7kqrl3rv	907	8	.	.	.
cord-347298-7kqrl3rv	908	1	In	in	IN
cord-347298-7kqrl3rv	908	2	the	the	DT
cord-347298-7kqrl3rv	908	3	mouse	mouse	NN
cord-347298-7kqrl3rv	908	4	,	,	,
cord-347298-7kqrl3rv	908	5	spermiation	spermiation	NN
cord-347298-7kqrl3rv	908	6	is	be	VBZ
cord-347298-7kqrl3rv	908	7	accompanied	accompany	VBN
cord-347298-7kqrl3rv	908	8	by	by	IN
cord-347298-7kqrl3rv	908	9	a	a	DT
cord-347298-7kqrl3rv	908	10	period	period	NN
cord-347298-7kqrl3rv	908	11	of	of	IN
cord-347298-7kqrl3rv	908	12	elevated	elevated	JJ
cord-347298-7kqrl3rv	908	13	nuclear	nuclear	JJ
cord-347298-7kqrl3rv	908	14	NFB	NFB	NNP
cord-347298-7kqrl3rv	908	15	levels	level	NNS
cord-347298-7kqrl3rv	908	16	in	in	IN
cord-347298-7kqrl3rv	908	17	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	908	18	(	(	-LRB-
cord-347298-7kqrl3rv	908	19	Delfino	Delfino	NNP
cord-347298-7kqrl3rv	908	20	and	and	CC
cord-347298-7kqrl3rv	908	21	Walker	Walker	NNP
cord-347298-7kqrl3rv	908	22	1998	1998	CD
cord-347298-7kqrl3rv	908	23	)	)	-RRB-
cord-347298-7kqrl3rv	908	24	.	.	.
cord-347298-7kqrl3rv	909	1	These	these	DT
cord-347298-7kqrl3rv	909	2	responses	response	NNS
cord-347298-7kqrl3rv	909	3	coincide	coincide	VBP
cord-347298-7kqrl3rv	909	4	with	with	IN
cord-347298-7kqrl3rv	909	5	a	a	DT
cord-347298-7kqrl3rv	909	6	peak	peak	NN
cord-347298-7kqrl3rv	909	7	of	of	IN
cord-347298-7kqrl3rv	909	8	DNA	dna	NN
cord-347298-7kqrl3rv	909	9	synthesis	synthesis	NN
cord-347298-7kqrl3rv	909	10	by	by	IN
cord-347298-7kqrl3rv	909	11	preleptotene	preleptotene	NNP
cord-347298-7kqrl3rv	909	12	spermatocytes	spermatocytes	NNP
cord-347298-7kqrl3rv	909	13	and	and	CC
cord-347298-7kqrl3rv	909	14	type	type	VB
cord-347298-7kqrl3rv	909	15	A	a	DT
cord-347298-7kqrl3rv	909	16	spermatogonia	spermatogonia	NN
cord-347298-7kqrl3rv	909	17	prior	prior	RB
cord-347298-7kqrl3rv	909	18	to	to	IN
cord-347298-7kqrl3rv	909	19	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	909	20	and	and	CC
cord-347298-7kqrl3rv	909	21	mitotic	mitotic	JJ
cord-347298-7kqrl3rv	909	22	division	division	NN
cord-347298-7kqrl3rv	909	23	,	,	,
cord-347298-7kqrl3rv	909	24	and	and	CC
cord-347298-7kqrl3rv	909	25	reorganization	reorganization	NN
cord-347298-7kqrl3rv	909	26	of	of	IN
cord-347298-7kqrl3rv	909	27	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	909	28	cell	cell	NN
cord-347298-7kqrl3rv	909	29	tight	tight	JJ
cord-347298-7kqrl3rv	909	30	junctions	junction	NNS
cord-347298-7kqrl3rv	909	31	to	to	TO
cord-347298-7kqrl3rv	909	32	allow	allow	VB
cord-347298-7kqrl3rv	909	33	the	the	DT
cord-347298-7kqrl3rv	909	34	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	909	35	cells	cell	NNS
cord-347298-7kqrl3rv	909	36	to	to	TO
cord-347298-7kqrl3rv	909	37	enter	enter	VB
cord-347298-7kqrl3rv	909	38	the	the	DT
cord-347298-7kqrl3rv	909	39	adluminal	adluminal	NNP
cord-347298-7kqrl3rv	909	40	compartment	compartment	NNP
cord-347298-7kqrl3rv	909	41	(	(	-LRB-
cord-347298-7kqrl3rv	909	42	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	909	43	and	and	CC
cord-347298-7kqrl3rv	909	44	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	909	45	2008	2008	CD
cord-347298-7kqrl3rv	909	46	)	)	-RRB-
cord-347298-7kqrl3rv	909	47	.	.	.
cord-347298-7kqrl3rv	910	1	Given	give	VBN
cord-347298-7kqrl3rv	910	2	that	that	DT
cord-347298-7kqrl3rv	910	3	IL1	IL1	NNP
cord-347298-7kqrl3rv	910	4	,	,	,
cord-347298-7kqrl3rv	910	5	IL6	IL6	NNP
cord-347298-7kqrl3rv	910	6	,	,	,
cord-347298-7kqrl3rv	910	7	and	and	CC
cord-347298-7kqrl3rv	910	8	activin	activin	NNP
cord-347298-7kqrl3rv	910	9	A	A	NNP
cord-347298-7kqrl3rv	910	10	are	be	VBP
cord-347298-7kqrl3rv	910	11	regulators	regulator	NNS
cord-347298-7kqrl3rv	910	12	of	of	IN
cord-347298-7kqrl3rv	910	13	spermatogonial	spermatogonial	JJ
cord-347298-7kqrl3rv	910	14	proliferation	proliferation	NN
cord-347298-7kqrl3rv	910	15	and	and	CC
cord-347298-7kqrl3rv	910	16	meiotic	meiotic	JJ
cord-347298-7kqrl3rv	910	17	progression	progression	NN
cord-347298-7kqrl3rv	911	1	(	(	-LRB-
cord-347298-7kqrl3rv	911	2	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	911	3	et	et	NNP
cord-347298-7kqrl3rv	911	4	al	al	NNP
cord-347298-7kqrl3rv	911	5	.	.	.
cord-347298-7kqrl3rv	911	6	1993a	1993a	CD
cord-347298-7kqrl3rv	912	1	(	(	-LRB-
cord-347298-7kqrl3rv	912	2	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	912	3	et	et	NNP
cord-347298-7kqrl3rv	912	4	al	al	NNP
cord-347298-7kqrl3rv	912	5	.	.	.
cord-347298-7kqrl3rv	913	1	,	,	,
cord-347298-7kqrl3rv	913	2	1995	1995	CD
cord-347298-7kqrl3rv	914	1	Mather	Mather	NNP
cord-347298-7kqrl3rv	914	2	et	et	NNP
cord-347298-7kqrl3rv	914	3	al	al	NNP
cord-347298-7kqrl3rv	914	4	.	.	.
cord-347298-7kqrl3rv	914	5	1990	1990	CD
cord-347298-7kqrl3rv	915	1	;	;	:
cord-347298-7kqrl3rv	915	2	Meehan	Meehan	NNP
cord-347298-7kqrl3rv	915	3	et	et	NNP
cord-347298-7kqrl3rv	915	4	al	al	NNP
cord-347298-7kqrl3rv	915	5	.	.	.
cord-347298-7kqrl3rv	916	1	2000	2000	CD
cord-347298-7kqrl3rv	917	1	;	;	:
cord-347298-7kqrl3rv	917	2	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	917	3	et	et	NNP
cord-347298-7kqrl3rv	917	4	al	al	NNP
cord-347298-7kqrl3rv	917	5	.	.	.
cord-347298-7kqrl3rv	918	1	2000	2000	CD
cord-347298-7kqrl3rv	918	2	;	;	:
cord-347298-7kqrl3rv	918	3	Parvinen	Parvinen	NNP
cord-347298-7kqrl3rv	918	4	et	et	NNP
cord-347298-7kqrl3rv	918	5	al	al	NNP
cord-347298-7kqrl3rv	918	6	.	.	.
cord-347298-7kqrl3rv	919	1	1991	1991	CD
cord-347298-7kqrl3rv	919	2	;	;	:
cord-347298-7kqrl3rv	919	3	Söder	Söder	NNP
cord-347298-7kqrl3rv	919	4	et	et	NNP
cord-347298-7kqrl3rv	919	5	al	al	NNP
cord-347298-7kqrl3rv	919	6	.	.	.
cord-347298-7kqrl3rv	919	7	1991	1991	CD
cord-347298-7kqrl3rv	919	8	)	)	-RRB-
cord-347298-7kqrl3rv	919	9	,	,	,
cord-347298-7kqrl3rv	919	10	while	while	IN
cord-347298-7kqrl3rv	919	11	TNF	TNF	NNP
cord-347298-7kqrl3rv	919	12	and	and	CC
cord-347298-7kqrl3rv	919	13	iNOS/	iNOS/	NNP
cord-347298-7kqrl3rv	919	14	NO	no	DT
cord-347298-7kqrl3rv	919	15	induce	induce	VB
cord-347298-7kqrl3rv	919	16	the	the	DT
cord-347298-7kqrl3rv	919	17	disassembly	disassembly	NN
cord-347298-7kqrl3rv	919	18	of	of	IN
cord-347298-7kqrl3rv	919	19	the	the	DT
cord-347298-7kqrl3rv	919	20	intercellular	intercellular	JJ
cord-347298-7kqrl3rv	919	21	tight	tight	JJ
cord-347298-7kqrl3rv	919	22	junctions	junction	NNS
cord-347298-7kqrl3rv	919	23	Lee	Lee	NNP
cord-347298-7kqrl3rv	919	24	et	et	NNP
cord-347298-7kqrl3rv	919	25	al	al	NNP
cord-347298-7kqrl3rv	919	26	.	.	NNP
cord-347298-7kqrl3rv	919	27	2005	2005	CD
cord-347298-7kqrl3rv	919	28	;	;	.
cord-347298-7kqrl3rv	920	1	Li	Li	NNP
cord-347298-7kqrl3rv	920	2	et	et	NNP
cord-347298-7kqrl3rv	920	3	al	al	NNP
cord-347298-7kqrl3rv	920	4	.	.	.
cord-347298-7kqrl3rv	921	1	2006a	2006a	CD
cord-347298-7kqrl3rv	921	2	;	;	:
cord-347298-7kqrl3rv	921	3	Siu	Siu	NNP
cord-347298-7kqrl3rv	921	4	et	et	NNP
cord-347298-7kqrl3rv	921	5	al	al	NNP
cord-347298-7kqrl3rv	921	6	.	.	NNP
cord-347298-7kqrl3rv	921	7	2003	2003	CD
cord-347298-7kqrl3rv	921	8	)	)	-RRB-
cord-347298-7kqrl3rv	922	1	,	,	,
cord-347298-7kqrl3rv	922	2	this	this	DT
cord-347298-7kqrl3rv	922	3	concurrence	concurrence	NN
cord-347298-7kqrl3rv	922	4	of	of	IN
cord-347298-7kqrl3rv	922	5	events	event	NNS
cord-347298-7kqrl3rv	922	6	is	be	VBZ
cord-347298-7kqrl3rv	922	7	unlikely	unlikely	JJ
cord-347298-7kqrl3rv	922	8	to	to	TO
cord-347298-7kqrl3rv	922	9	be	be	VB
cord-347298-7kqrl3rv	922	10	a	a	DT
cord-347298-7kqrl3rv	922	11	coincidence	coincidence	NN
cord-347298-7kqrl3rv	922	12	.	.	.
cord-347298-7kqrl3rv	923	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	923	2	would	would	MD
cord-347298-7kqrl3rv	923	3	appear	appear	VB
cord-347298-7kqrl3rv	923	4	that	that	DT
cord-347298-7kqrl3rv	923	5	release	release	NN
cord-347298-7kqrl3rv	923	6	of	of	IN
cord-347298-7kqrl3rv	923	7	the	the	DT
cord-347298-7kqrl3rv	923	8	spermatozoa	spermatozoon	NNS
cord-347298-7kqrl3rv	923	9	and/or	and/or	CC
cord-347298-7kqrl3rv	923	10	phagocytosis	phagocytosis	NN
cord-347298-7kqrl3rv	923	11	of	of	IN
cord-347298-7kqrl3rv	923	12	the	the	DT
cord-347298-7kqrl3rv	923	13	residual	residual	JJ
cord-347298-7kqrl3rv	923	14	cytoplasm	cytoplasm	NN
cord-347298-7kqrl3rv	923	15	triggers	trigger	VBZ
cord-347298-7kqrl3rv	923	16	elements	element	NNS
cord-347298-7kqrl3rv	923	17	of	of	IN
cord-347298-7kqrl3rv	923	18	the	the	DT
cord-347298-7kqrl3rv	923	19	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	923	20	machinery	machinery	NN
cord-347298-7kqrl3rv	923	21	within	within	IN
cord-347298-7kqrl3rv	923	22	the	the	DT
cord-347298-7kqrl3rv	923	23	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	923	24	epithelium	epithelium	NN
cord-347298-7kqrl3rv	923	25	.	.	.
cord-347298-7kqrl3rv	924	1	A	a	DT
cord-347298-7kqrl3rv	924	2	role	role	NN
cord-347298-7kqrl3rv	924	3	for	for	IN
cord-347298-7kqrl3rv	924	4	TLRs	tlr	NNS
cord-347298-7kqrl3rv	924	5	or	or	CC
cord-347298-7kqrl3rv	924	6	other	other	JJ
cord-347298-7kqrl3rv	924	7	patternrecognition	patternrecognition	NN
cord-347298-7kqrl3rv	924	8	receptors	receptor	NNS
cord-347298-7kqrl3rv	924	9	in	in	IN
cord-347298-7kqrl3rv	924	10	this	this	DT
cord-347298-7kqrl3rv	924	11	process	process	NN
cord-347298-7kqrl3rv	924	12	may	may	MD
cord-347298-7kqrl3rv	924	13	be	be	VB
cord-347298-7kqrl3rv	924	14	postulated	postulate	VBN
cord-347298-7kqrl3rv	924	15	,	,	,
cord-347298-7kqrl3rv	924	16	and	and	CC
cord-347298-7kqrl3rv	924	17	similar	similar	JJ
cord-347298-7kqrl3rv	924	18	regulatory	regulatory	JJ
cord-347298-7kqrl3rv	924	19	networks	network	NNS
cord-347298-7kqrl3rv	924	20	may	may	MD
cord-347298-7kqrl3rv	924	21	also	also	RB
cord-347298-7kqrl3rv	924	22	operate	operate	VB
cord-347298-7kqrl3rv	924	23	throughout	throughout	IN
cord-347298-7kqrl3rv	924	24	the	the	DT
cord-347298-7kqrl3rv	924	25	remainder	remainder	NN
cord-347298-7kqrl3rv	924	26	of	of	IN
cord-347298-7kqrl3rv	924	27	the	the	DT
cord-347298-7kqrl3rv	924	28	cycle	cycle	NN
cord-347298-7kqrl3rv	924	29	.	.	.
cord-347298-7kqrl3rv	925	1	Many	many	JJ
cord-347298-7kqrl3rv	925	2	questions	question	NNS
cord-347298-7kqrl3rv	925	3	regarding	regard	VBG
cord-347298-7kqrl3rv	925	4	the	the	DT
cord-347298-7kqrl3rv	925	5	details	detail	NNS
cord-347298-7kqrl3rv	925	6	of	of	IN
cord-347298-7kqrl3rv	925	7	this	this	DT
cord-347298-7kqrl3rv	925	8	functional	functional	JJ
cord-347298-7kqrl3rv	925	9	regulation	regulation	NN
cord-347298-7kqrl3rv	925	10	await	await	VBP
cord-347298-7kqrl3rv	925	11	clarification	clarification	NN
cord-347298-7kqrl3rv	925	12	,	,	,
cord-347298-7kqrl3rv	925	13	and	and	CC
cord-347298-7kqrl3rv	925	14	it	-PRON-	PRP
cord-347298-7kqrl3rv	925	15	must	must	MD
cord-347298-7kqrl3rv	925	16	be	be	VB
cord-347298-7kqrl3rv	925	17	noted	note	VBN
cord-347298-7kqrl3rv	925	18	that	that	IN
cord-347298-7kqrl3rv	925	19	there	there	EX
cord-347298-7kqrl3rv	925	20	is	be	VBZ
cord-347298-7kqrl3rv	925	21	a	a	DT
cord-347298-7kqrl3rv	925	22	curious	curious	JJ
cord-347298-7kqrl3rv	925	23	lack	lack	NN
cord-347298-7kqrl3rv	925	24	of	of	IN
cord-347298-7kqrl3rv	925	25	concordance	concordance	NN
cord-347298-7kqrl3rv	925	26	between	between	IN
cord-347298-7kqrl3rv	925	27	the	the	DT
cord-347298-7kqrl3rv	925	28	content	content	NN
cord-347298-7kqrl3rv	925	29	of	of	IN
cord-347298-7kqrl3rv	925	30	NFB	NFB	NNP
cord-347298-7kqrl3rv	925	31	in	in	IN
cord-347298-7kqrl3rv	925	32	the	the	DT
cord-347298-7kqrl3rv	925	33	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	925	34	cell	cell	NN
cord-347298-7kqrl3rv	925	35	nucleus	nucleus	NN
cord-347298-7kqrl3rv	925	36	observed	observe	VBD
cord-347298-7kqrl3rv	925	37	across	across	IN
cord-347298-7kqrl3rv	925	38	the	the	DT
cord-347298-7kqrl3rv	925	39	cycle	cycle	NN
cord-347298-7kqrl3rv	925	40	in	in	IN
cord-347298-7kqrl3rv	925	41	the	the	DT
cord-347298-7kqrl3rv	925	42	mouse	mouse	NN
cord-347298-7kqrl3rv	925	43	(	(	-LRB-
cord-347298-7kqrl3rv	925	44	Delfino	Delfino	NNP
cord-347298-7kqrl3rv	925	45	and	and	CC
cord-347298-7kqrl3rv	925	46	Walker	Walker	NNP
cord-347298-7kqrl3rv	925	47	1998	1998	CD
cord-347298-7kqrl3rv	925	48	)	)	-RRB-
cord-347298-7kqrl3rv	925	49	and	and	CC
cord-347298-7kqrl3rv	925	50	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	925	51	cytokine	cytokine	NN
cord-347298-7kqrl3rv	925	52	production	production	NN
cord-347298-7kqrl3rv	925	53	by	by	IN
cord-347298-7kqrl3rv	925	54	these	these	DT
cord-347298-7kqrl3rv	925	55	same	same	JJ
cord-347298-7kqrl3rv	925	56	cells	cell	NNS
cord-347298-7kqrl3rv	925	57	in	in	IN
cord-347298-7kqrl3rv	925	58	the	the	DT
cord-347298-7kqrl3rv	925	59	rat	rat	NN
cord-347298-7kqrl3rv	925	60	Hakovirta	Hakovirta	NNP
cord-347298-7kqrl3rv	925	61	et	et	NNP
cord-347298-7kqrl3rv	925	62	al	al	NNP
cord-347298-7kqrl3rv	925	63	.	.	NNP
cord-347298-7kqrl3rv	925	64	1995	1995	CD
cord-347298-7kqrl3rv	925	65	;	;	:
cord-347298-7kqrl3rv	925	66	Kaipia	Kaipia	NNP
cord-347298-7kqrl3rv	925	67	et	et	NNP
cord-347298-7kqrl3rv	925	68	al	al	NNP
cord-347298-7kqrl3rv	925	69	.	.	.
cord-347298-7kqrl3rv	925	70	1992	1992	CD
cord-347298-7kqrl3rv	925	71	;	;	:
cord-347298-7kqrl3rv	925	72	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	925	73	et	et	NNP
cord-347298-7kqrl3rv	925	74	al	al	NNP
cord-347298-7kqrl3rv	925	75	.	.	NNP
cord-347298-7kqrl3rv	925	76	2000a	2000a	CD
cord-347298-7kqrl3rv	925	77	;	;	:
cord-347298-7kqrl3rv	925	78	Okuma	Okuma	NNP
cord-347298-7kqrl3rv	925	79	et	et	NNP
cord-347298-7kqrl3rv	925	80	al	al	NNP
cord-347298-7kqrl3rv	925	81	.	.	.
cord-347298-7kqrl3rv	926	1	2006	2006	CD
cord-347298-7kqrl3rv	926	2	;	;	:
cord-347298-7kqrl3rv	926	3	Söder	Söder	NNP
cord-347298-7kqrl3rv	926	4	et	et	NNP
cord-347298-7kqrl3rv	926	5	al	al	NNP
cord-347298-7kqrl3rv	926	6	.	.	.
cord-347298-7kqrl3rv	927	1	1991	1991	CD
cord-347298-7kqrl3rv	927	2	;	;	:
cord-347298-7kqrl3rv	927	3	Syed	Syed	NNP
cord-347298-7kqrl3rv	927	4	et	et	NNP
cord-347298-7kqrl3rv	927	5	al	al	NNP
cord-347298-7kqrl3rv	927	6	.	.	.
cord-347298-7kqrl3rv	927	7	1993	1993	CD
cord-347298-7kqrl3rv	927	8	)	)	-RRB-
cord-347298-7kqrl3rv	927	9	.	.	.
cord-347298-7kqrl3rv	928	1	Regardless	regardless	RB
cord-347298-7kqrl3rv	928	2	of	of	IN
cord-347298-7kqrl3rv	928	3	the	the	DT
cord-347298-7kqrl3rv	928	4	questions	question	NNS
cord-347298-7kqrl3rv	928	5	that	that	WDT
cord-347298-7kqrl3rv	928	6	remain	remain	VBP
cord-347298-7kqrl3rv	928	7	,	,	,
cord-347298-7kqrl3rv	928	8	however	however	RB
cord-347298-7kqrl3rv	928	9	,	,	,
cord-347298-7kqrl3rv	928	10	key	key	JJ
cord-347298-7kqrl3rv	928	11	elements	element	NNS
cord-347298-7kqrl3rv	928	12	of	of	IN
cord-347298-7kqrl3rv	928	13	the	the	DT
cord-347298-7kqrl3rv	928	14	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	928	15	response	response	NN
cord-347298-7kqrl3rv	928	16	appear	appear	VBP
cord-347298-7kqrl3rv	928	17	to	to	TO
cord-347298-7kqrl3rv	928	18	play	play	VB
cord-347298-7kqrl3rv	928	19	essential	essential	JJ
cord-347298-7kqrl3rv	928	20	roles	role	NNS
cord-347298-7kqrl3rv	928	21	in	in	IN
cord-347298-7kqrl3rv	928	22	the	the	DT
cord-347298-7kqrl3rv	928	23	physiological	physiological	JJ
cord-347298-7kqrl3rv	928	24	regulation	regulation	NN
cord-347298-7kqrl3rv	928	25	of	of	IN
cord-347298-7kqrl3rv	928	26	the	the	DT
cord-347298-7kqrl3rv	928	27	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	928	28	epithelium	epithelium	NN
cord-347298-7kqrl3rv	928	29	,	,	,
cord-347298-7kqrl3rv	928	30	which	which	WDT
cord-347298-7kqrl3rv	928	31	are	be	VBP
cord-347298-7kqrl3rv	928	32	entirely	entirely	RB
cord-347298-7kqrl3rv	928	33	separate	separate	JJ
cord-347298-7kqrl3rv	928	34	from	from	IN
cord-347298-7kqrl3rv	928	35	their	-PRON-	PRP$
cord-347298-7kqrl3rv	928	36	roles	role	NNS
cord-347298-7kqrl3rv	928	37	in	in	IN
cord-347298-7kqrl3rv	928	38	pathology	pathology	NN
cord-347298-7kqrl3rv	928	39	.	.	.
cord-347298-7kqrl3rv	929	1	Although	although	IN
cord-347298-7kqrl3rv	929	2	it	-PRON-	PRP
cord-347298-7kqrl3rv	929	3	is	be	VBZ
cord-347298-7kqrl3rv	929	4	a	a	DT
cord-347298-7kqrl3rv	929	5	common	common	JJ
cord-347298-7kqrl3rv	929	6	assumption	assumption	NN
cord-347298-7kqrl3rv	929	7	that	that	IN
cord-347298-7kqrl3rv	929	8	male	male	JJ
cord-347298-7kqrl3rv	929	9	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	929	10	failure	failure	NN
cord-347298-7kqrl3rv	929	11	caused	cause	VBN
cord-347298-7kqrl3rv	929	12	by	by	IN
cord-347298-7kqrl3rv	929	13	local	local	JJ
cord-347298-7kqrl3rv	929	14	or	or	CC
cord-347298-7kqrl3rv	929	15	systemic	systemic	JJ
cord-347298-7kqrl3rv	929	16	illness	illness	NN
cord-347298-7kqrl3rv	929	17	,	,	,
cord-347298-7kqrl3rv	929	18	infection	infection	NN
cord-347298-7kqrl3rv	929	19	,	,	,
cord-347298-7kqrl3rv	929	20	and	and	CC
cord-347298-7kqrl3rv	929	21	chronic	chronic	JJ
cord-347298-7kqrl3rv	929	22	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	929	23	disease	disease	NN
cord-347298-7kqrl3rv	929	24	is	be	VBZ
cord-347298-7kqrl3rv	929	25	due	due	JJ
cord-347298-7kqrl3rv	929	26	to	to	IN
cord-347298-7kqrl3rv	929	27	the	the	DT
cord-347298-7kqrl3rv	929	28	negative	negative	JJ
cord-347298-7kqrl3rv	929	29	effects	effect	NNS
cord-347298-7kqrl3rv	929	30	of	of	IN
cord-347298-7kqrl3rv	929	31	raised	raise	VBN
cord-347298-7kqrl3rv	929	32	body	body	NN
cord-347298-7kqrl3rv	929	33	temperature	temperature	NN
cord-347298-7kqrl3rv	929	34	on	on	IN
cord-347298-7kqrl3rv	929	35	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	929	36	,	,	,
cord-347298-7kqrl3rv	929	37	there	there	EX
cord-347298-7kqrl3rv	929	38	is	be	VBZ
cord-347298-7kqrl3rv	929	39	little	little	JJ
cord-347298-7kqrl3rv	929	40	clinical	clinical	JJ
cord-347298-7kqrl3rv	929	41	or	or	CC
cord-347298-7kqrl3rv	929	42	experimental	experimental	JJ
cord-347298-7kqrl3rv	929	43	evidence	evidence	NN
cord-347298-7kqrl3rv	929	44	to	to	TO
cord-347298-7kqrl3rv	929	45	support	support	VB
cord-347298-7kqrl3rv	929	46	this	this	DT
cord-347298-7kqrl3rv	929	47	belief	belief	NN
cord-347298-7kqrl3rv	929	48	(	(	-LRB-
cord-347298-7kqrl3rv	929	49	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	929	50	et	et	NNP
cord-347298-7kqrl3rv	929	51	al	al	NNP
cord-347298-7kqrl3rv	929	52	.	.	NNP
cord-347298-7kqrl3rv	929	53	2000b	2000b	CD
cord-347298-7kqrl3rv	929	54	)	)	-RRB-
cord-347298-7kqrl3rv	929	55	.	.	.
cord-347298-7kqrl3rv	930	1	There	there	EX
cord-347298-7kqrl3rv	930	2	is	be	VBZ
cord-347298-7kqrl3rv	930	3	much	much	RB
cord-347298-7kqrl3rv	930	4	more	more	RBR
cord-347298-7kqrl3rv	930	5	convincing	convincing	JJ
cord-347298-7kqrl3rv	930	6	evidence	evidence	NN
cord-347298-7kqrl3rv	930	7	that	that	IN
cord-347298-7kqrl3rv	930	8	the	the	DT
cord-347298-7kqrl3rv	930	9	damage	damage	NN
cord-347298-7kqrl3rv	930	10	is	be	VBZ
cord-347298-7kqrl3rv	930	11	due	due	JJ
cord-347298-7kqrl3rv	930	12	to	to	IN
cord-347298-7kqrl3rv	930	13	activation	activation	NN
cord-347298-7kqrl3rv	930	14	of	of	IN
cord-347298-7kqrl3rv	930	15	local	local	JJ
cord-347298-7kqrl3rv	930	16	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	930	17	pathways	pathway	NNS
cord-347298-7kqrl3rv	930	18	and	and	CC
cord-347298-7kqrl3rv	930	19	the	the	DT
cord-347298-7kqrl3rv	930	20	activity	activity	NN
cord-347298-7kqrl3rv	930	21	of	of	IN
cord-347298-7kqrl3rv	930	22	immune	immune	JJ
cord-347298-7kqrl3rv	930	23	cells	cell	NNS
cord-347298-7kqrl3rv	930	24	recruited	recruit	VBN
cord-347298-7kqrl3rv	930	25	during	during	IN
cord-347298-7kqrl3rv	930	26	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	930	27	events	event	NNS
cord-347298-7kqrl3rv	930	28	.	.	.
cord-347298-7kqrl3rv	931	1	As	as	IN
cord-347298-7kqrl3rv	931	2	already	already	RB
cord-347298-7kqrl3rv	931	3	outlined	outline	VBN
cord-347298-7kqrl3rv	931	4	in	in	IN
cord-347298-7kqrl3rv	931	5	the	the	DT
cord-347298-7kqrl3rv	931	6	previous	previous	JJ
cord-347298-7kqrl3rv	931	7	sections	section	NNS
cord-347298-7kqrl3rv	931	8	,	,	,
cord-347298-7kqrl3rv	931	9	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	931	10	mediators	mediator	NNS
cord-347298-7kqrl3rv	931	11	such	such	JJ
cord-347298-7kqrl3rv	931	12	as	as	IN
cord-347298-7kqrl3rv	931	13	IL1	IL1	NNP
cord-347298-7kqrl3rv	931	14	,	,	,
cord-347298-7kqrl3rv	931	15	ROS	ROS	NNP
cord-347298-7kqrl3rv	931	16	,	,	,
cord-347298-7kqrl3rv	931	17	TNF	TNF	NNP
cord-347298-7kqrl3rv	931	18	,	,	,
cord-347298-7kqrl3rv	931	19	and	and	CC
cord-347298-7kqrl3rv	931	20	NO	no	UH
cord-347298-7kqrl3rv	931	21	,	,	,
cord-347298-7kqrl3rv	931	22	as	as	RB
cord-347298-7kqrl3rv	931	23	well	well	RB
cord-347298-7kqrl3rv	931	24	as	as	IN
cord-347298-7kqrl3rv	931	25	glucocorticoids	glucocorticoid	NNS
cord-347298-7kqrl3rv	931	26	produced	produce	VBN
cord-347298-7kqrl3rv	931	27	in	in	IN
cord-347298-7kqrl3rv	931	28	response	response	NN
cord-347298-7kqrl3rv	931	29	to	to	IN
cord-347298-7kqrl3rv	931	30	inflammation	inflammation	NN
cord-347298-7kqrl3rv	931	31	,	,	,
cord-347298-7kqrl3rv	931	32	have	have	VBP
cord-347298-7kqrl3rv	931	33	mostly	mostly	RB
cord-347298-7kqrl3rv	931	34	negative	negative	JJ
cord-347298-7kqrl3rv	931	35	effects	effect	NNS
cord-347298-7kqrl3rv	931	36	at	at	IN
cord-347298-7kqrl3rv	931	37	all	all	DT
cord-347298-7kqrl3rv	931	38	levels	level	NNS
cord-347298-7kqrl3rv	931	39	of	of	IN
cord-347298-7kqrl3rv	931	40	the	the	DT
cord-347298-7kqrl3rv	931	41	hypothalamic	hypothalamic	JJ
cord-347298-7kqrl3rv	931	42	-	-	HYPH
cord-347298-7kqrl3rv	931	43	pituitary	pituitary	NN
cord-347298-7kqrl3rv	931	44	-	-	HYPH
cord-347298-7kqrl3rv	931	45	Leydig	leydig	NN
cord-347298-7kqrl3rv	931	46	cell	cell	NN
cord-347298-7kqrl3rv	931	47	axis	axis	NN
cord-347298-7kqrl3rv	931	48	(	(	-LRB-
cord-347298-7kqrl3rv	931	49	Bambino	Bambino	NNP
cord-347298-7kqrl3rv	931	50	and	and	CC
cord-347298-7kqrl3rv	931	51	Hsueh	Hsueh	NNP
cord-347298-7kqrl3rv	931	52	1981	1981	CD
cord-347298-7kqrl3rv	931	53	;	;	:
cord-347298-7kqrl3rv	932	1	Del	Del	NNP
cord-347298-7kqrl3rv	932	2	Punta	Punta	NNP
cord-347298-7kqrl3rv	932	3	et	et	NNP
cord-347298-7kqrl3rv	932	4	al	al	NNP
cord-347298-7kqrl3rv	932	5	.	.	.
cord-347298-7kqrl3rv	933	1	1996	1996	CD
cord-347298-7kqrl3rv	933	2	;	;	:
cord-347298-7kqrl3rv	933	3	Hales	Hales	NNP
cord-347298-7kqrl3rv	933	4	1992	1992	CD
cord-347298-7kqrl3rv	933	5	;	;	:
cord-347298-7kqrl3rv	933	6	Hales	Hales	NNP
cord-347298-7kqrl3rv	933	7	and	and	CC
cord-347298-7kqrl3rv	933	8	Payne	Payne	NNP
cord-347298-7kqrl3rv	933	9	1989	1989	CD
cord-347298-7kqrl3rv	933	10	;	;	:
cord-347298-7kqrl3rv	933	11	Hardy	Hardy	NNP
cord-347298-7kqrl3rv	933	12	et	et	NNP
cord-347298-7kqrl3rv	933	13	al	al	NNP
cord-347298-7kqrl3rv	933	14	.	.	.
cord-347298-7kqrl3rv	934	1	2005	2005	CD
cord-347298-7kqrl3rv	934	2	;	;	:
cord-347298-7kqrl3rv	934	3	Li	Li	NNP
cord-347298-7kqrl3rv	934	4	et	et	NNP
cord-347298-7kqrl3rv	934	5	al	al	NNP
cord-347298-7kqrl3rv	934	6	.	.	NNP
cord-347298-7kqrl3rv	934	7	1995	1995	CD
cord-347298-7kqrl3rv	934	8	;	;	:
cord-347298-7kqrl3rv	934	9	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	934	10	et	et	NNP
cord-347298-7kqrl3rv	934	11	al	al	NNP
cord-347298-7kqrl3rv	934	12	.	.	.
cord-347298-7kqrl3rv	935	1	1991b	1991b	CD
cord-347298-7kqrl3rv	936	1	Mauduit	Mauduit	NNP
cord-347298-7kqrl3rv	936	2	et	et	NNP
cord-347298-7kqrl3rv	936	3	al	al	NNP
cord-347298-7kqrl3rv	936	4	.	.	.
cord-347298-7kqrl3rv	937	1	,	,	,
cord-347298-7kqrl3rv	937	2	1998	1998	CD
cord-347298-7kqrl3rv	937	3	Monder	Monder	NNP
cord-347298-7kqrl3rv	937	4	et	et	NNP
cord-347298-7kqrl3rv	937	5	al	al	NNP
cord-347298-7kqrl3rv	937	6	.	.	.
cord-347298-7kqrl3rv	937	7	1994	1994	CD
cord-347298-7kqrl3rv	938	1	;	;	:
cord-347298-7kqrl3rv	938	2	Sharma	Sharma	NNP
cord-347298-7kqrl3rv	938	3	et	et	NNP
cord-347298-7kqrl3rv	938	4	al	al	NNP
cord-347298-7kqrl3rv	938	5	.	.	.
cord-347298-7kqrl3rv	939	1	1998	1998	CD
cord-347298-7kqrl3rv	939	2	;	;	:
cord-347298-7kqrl3rv	939	3	Welch	Welch	NNP
cord-347298-7kqrl3rv	939	4	et	et	NNP
cord-347298-7kqrl3rv	939	5	al	al	NNP
cord-347298-7kqrl3rv	939	6	.	.	NNP
cord-347298-7kqrl3rv	939	7	1995	1995	CD
cord-347298-7kqrl3rv	939	8	;	;	:
cord-347298-7kqrl3rv	939	9	Xiong	Xiong	NNP
cord-347298-7kqrl3rv	939	10	and	and	CC
cord-347298-7kqrl3rv	939	11	Hales	Hales	NNP
cord-347298-7kqrl3rv	939	12	1993b	1993b	CD
cord-347298-7kqrl3rv	939	13	.	.	.
cord-347298-7kqrl3rv	940	1	The	the	DT
cord-347298-7kqrl3rv	940	2	subsequent	subsequent	JJ
cord-347298-7kqrl3rv	940	3	reduction	reduction	NN
cord-347298-7kqrl3rv	940	4	in	in	IN
cord-347298-7kqrl3rv	940	5	androgen	androgen	NN
cord-347298-7kqrl3rv	940	6	production	production	NN
cord-347298-7kqrl3rv	940	7	may	may	MD
cord-347298-7kqrl3rv	940	8	lead	lead	VB
cord-347298-7kqrl3rv	940	9	to	to	IN
cord-347298-7kqrl3rv	940	10	reduced	reduce	VBN
cord-347298-7kqrl3rv	940	11	spermatogenic	spermatogenic	NN
cord-347298-7kqrl3rv	940	12	capacity	capacity	NN
cord-347298-7kqrl3rv	940	13	,	,	,
cord-347298-7kqrl3rv	940	14	but	but	CC
cord-347298-7kqrl3rv	940	15	may	may	MD
cord-347298-7kqrl3rv	940	16	also	also	RB
cord-347298-7kqrl3rv	940	17	exacerbate	exacerbate	VB
cord-347298-7kqrl3rv	940	18	the	the	DT
cord-347298-7kqrl3rv	940	19	effects	effect	NNS
cord-347298-7kqrl3rv	940	20	of	of	IN
cord-347298-7kqrl3rv	940	21	inflammation	inflammation	NN
cord-347298-7kqrl3rv	940	22	on	on	IN
cord-347298-7kqrl3rv	940	23	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	940	24	itself	-PRON-	PRP
cord-347298-7kqrl3rv	940	25	.	.	.
cord-347298-7kqrl3rv	941	1	Expression	expression	NN
cord-347298-7kqrl3rv	941	2	of	of	IN
cord-347298-7kqrl3rv	941	3	TLRs	TLRs	NNP
cord-347298-7kqrl3rv	941	4	on	on	IN
cord-347298-7kqrl3rv	941	5	the	the	DT
cord-347298-7kqrl3rv	941	6	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	941	7	cells	cell	NNS
cord-347298-7kqrl3rv	941	8	is	be	VBZ
cord-347298-7kqrl3rv	941	9	obviously	obviously	RB
cord-347298-7kqrl3rv	941	10	important	important	JJ
cord-347298-7kqrl3rv	941	11	in	in	IN
cord-347298-7kqrl3rv	941	12	protective	protective	JJ
cord-347298-7kqrl3rv	941	13	responses	response	NNS
cord-347298-7kqrl3rv	941	14	against	against	IN
cord-347298-7kqrl3rv	941	15	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	941	16	,	,	,
cord-347298-7kqrl3rv	941	17	but	but	CC
cord-347298-7kqrl3rv	941	18	also	also	RB
cord-347298-7kqrl3rv	941	19	provides	provide	VBZ
cord-347298-7kqrl3rv	941	20	a	a	DT
cord-347298-7kqrl3rv	941	21	mechanism	mechanism	NN
cord-347298-7kqrl3rv	941	22	whereby	whereby	WRB
cord-347298-7kqrl3rv	941	23	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	941	24	can	can	MD
cord-347298-7kqrl3rv	941	25	directly	directly	RB
cord-347298-7kqrl3rv	941	26	inhibit	inhibit	VB
cord-347298-7kqrl3rv	941	27	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	941	28	.	.	.
cord-347298-7kqrl3rv	942	1	Thus	thus	RB
cord-347298-7kqrl3rv	942	2	,	,	,
cord-347298-7kqrl3rv	942	3	TLR	TLR	NNP
cord-347298-7kqrl3rv	942	4	activation	activation	NN
cord-347298-7kqrl3rv	942	5	and	and	CC
cord-347298-7kqrl3rv	942	6	the	the	DT
cord-347298-7kqrl3rv	942	7	production	production	NN
cord-347298-7kqrl3rv	942	8	of	of	IN
cord-347298-7kqrl3rv	942	9	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	942	10	mediators	mediator	NNS
cord-347298-7kqrl3rv	942	11	almost	almost	RB
cord-347298-7kqrl3rv	942	12	certainly	certainly	RB
cord-347298-7kqrl3rv	942	13	alter	alter	VBP
cord-347298-7kqrl3rv	942	14	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	942	15	cell	cell	NN
cord-347298-7kqrl3rv	942	16	functions	function	NNS
cord-347298-7kqrl3rv	942	17	,	,	,
cord-347298-7kqrl3rv	942	18	and	and	CC
cord-347298-7kqrl3rv	942	19	this	this	DT
cord-347298-7kqrl3rv	942	20	will	will	MD
cord-347298-7kqrl3rv	942	21	affect	affect	VB
cord-347298-7kqrl3rv	942	22	the	the	DT
cord-347298-7kqrl3rv	942	23	ability	ability	NN
cord-347298-7kqrl3rv	942	24	of	of	IN
cord-347298-7kqrl3rv	942	25	these	these	DT
cord-347298-7kqrl3rv	942	26	cells	cell	NNS
cord-347298-7kqrl3rv	942	27	to	to	TO
cord-347298-7kqrl3rv	942	28	support	support	VB
cord-347298-7kqrl3rv	942	29	and	and	CC
cord-347298-7kqrl3rv	942	30	regulate	regulate	VB
cord-347298-7kqrl3rv	942	31	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	942	32	,	,	,
cord-347298-7kqrl3rv	942	33	as	as	RB
cord-347298-7kqrl3rv	942	34	well	well	RB
cord-347298-7kqrl3rv	942	35	as	as	IN
cord-347298-7kqrl3rv	942	36	activate	activate	VB
cord-347298-7kqrl3rv	942	37	signaling	signal	VBG
cord-347298-7kqrl3rv	942	38	pathways	pathway	NNS
cord-347298-7kqrl3rv	942	39	that	that	WDT
cord-347298-7kqrl3rv	942	40	promote	promote	VBP
cord-347298-7kqrl3rv	942	41	germ	germ	NN
cord-347298-7kqrl3rv	942	42	cell	cell	NN
cord-347298-7kqrl3rv	942	43	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	942	44	(	(	-LRB-
cord-347298-7kqrl3rv	942	45	Lysiak	Lysiak	NNP
cord-347298-7kqrl3rv	942	46	et	et	FW
cord-347298-7kqrl3rv	942	47	al	al	NNP
cord-347298-7kqrl3rv	942	48	.	.	NNP
cord-347298-7kqrl3rv	942	49	2005	2005	CD
cord-347298-7kqrl3rv	942	50	;	;	.
cord-347298-7kqrl3rv	943	1	Pentikäinen	Pentikäinen	NNP
cord-347298-7kqrl3rv	943	2	et	et	NNP
cord-347298-7kqrl3rv	943	3	al	al	NNP
cord-347298-7kqrl3rv	943	4	.	.	.
cord-347298-7kqrl3rv	944	1	2002	2002	CD
cord-347298-7kqrl3rv	944	2	;	;	:
cord-347298-7kqrl3rv	944	3	Rasoulpour	Rasoulpour	NNP
cord-347298-7kqrl3rv	944	4	and	and	CC
cord-347298-7kqrl3rv	944	5	Boekelheide	Boekelheide	NNP
cord-347298-7kqrl3rv	944	6	2005	2005	CD
cord-347298-7kqrl3rv	944	7	;	;	:
cord-347298-7kqrl3rv	944	8	Starace	Starace	NNP
cord-347298-7kqrl3rv	944	9	et	et	NNP
cord-347298-7kqrl3rv	944	10	al	al	NNP
cord-347298-7kqrl3rv	944	11	.	.	NNP
cord-347298-7kqrl3rv	944	12	2005	2005	CD
cord-347298-7kqrl3rv	944	13	)	)	-RRB-
cord-347298-7kqrl3rv	944	14	.	.	.
cord-347298-7kqrl3rv	945	1	Inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	945	2	events	event	NNS
cord-347298-7kqrl3rv	945	3	play	play	VBP
cord-347298-7kqrl3rv	945	4	a	a	DT
cord-347298-7kqrl3rv	945	5	role	role	NN
cord-347298-7kqrl3rv	945	6	in	in	IN
cord-347298-7kqrl3rv	945	7	testicular	testicular	JJ
cord-347298-7kqrl3rv	945	8	damage	damage	NN
cord-347298-7kqrl3rv	945	9	due	due	IN
cord-347298-7kqrl3rv	945	10	to	to	IN
cord-347298-7kqrl3rv	945	11	vascular	vascular	JJ
cord-347298-7kqrl3rv	945	12	disturbance	disturbance	NN
cord-347298-7kqrl3rv	945	13	.	.	.
cord-347298-7kqrl3rv	946	1	Spermatogenesis	Spermatogenesis	NNP
cord-347298-7kqrl3rv	946	2	is	be	VBZ
cord-347298-7kqrl3rv	946	3	an	an	DT
cord-347298-7kqrl3rv	946	4	energy	energy	NN
cord-347298-7kqrl3rv	946	5	intensive	intensive	JJ
cord-347298-7kqrl3rv	946	6	process	process	NN
cord-347298-7kqrl3rv	946	7	,	,	,
cord-347298-7kqrl3rv	946	8	and	and	CC
cord-347298-7kqrl3rv	946	9	the	the	DT
cord-347298-7kqrl3rv	946	10	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	946	11	epithelium	epithelium	NN
cord-347298-7kqrl3rv	946	12	is	be	VBZ
cord-347298-7kqrl3rv	946	13	not	not	RB
cord-347298-7kqrl3rv	946	14	vascularized	vascularized	JJ
cord-347298-7kqrl3rv	946	15	.	.	.
cord-347298-7kqrl3rv	947	1	Consequently	consequently	RB
cord-347298-7kqrl3rv	947	2	,	,	,
cord-347298-7kqrl3rv	947	3	unobstructed	unobstructed	JJ
cord-347298-7kqrl3rv	947	4	blood	blood	NN
cord-347298-7kqrl3rv	947	5	flow	flow	NN
cord-347298-7kqrl3rv	947	6	to	to	IN
cord-347298-7kqrl3rv	947	7	the	the	DT
cord-347298-7kqrl3rv	947	8	testis	testis	NN
cord-347298-7kqrl3rv	947	9	is	be	VBZ
cord-347298-7kqrl3rv	947	10	essential	essential	JJ
cord-347298-7kqrl3rv	947	11	and	and	CC
cord-347298-7kqrl3rv	947	12	even	even	RB
cord-347298-7kqrl3rv	947	13	minor	minor	JJ
cord-347298-7kqrl3rv	947	14	anomalies	anomaly	NNS
cord-347298-7kqrl3rv	947	15	in	in	IN
cord-347298-7kqrl3rv	947	16	the	the	DT
cord-347298-7kqrl3rv	947	17	testicular	testicular	NN
cord-347298-7kqrl3rv	947	18	vasculature	vasculature	NN
cord-347298-7kqrl3rv	947	19	,	,	,
cord-347298-7kqrl3rv	947	20	such	such	JJ
cord-347298-7kqrl3rv	947	21	as	as	IN
cord-347298-7kqrl3rv	947	22	varicocele	varicocele	NN
cord-347298-7kqrl3rv	947	23	,	,	,
cord-347298-7kqrl3rv	947	24	have	have	VBP
cord-347298-7kqrl3rv	947	25	cumulative	cumulative	JJ
cord-347298-7kqrl3rv	947	26	negative	negative	JJ
cord-347298-7kqrl3rv	947	27	effects	effect	NNS
cord-347298-7kqrl3rv	947	28	on	on	IN
cord-347298-7kqrl3rv	947	29	sperm	sperm	NN
cord-347298-7kqrl3rv	947	30	production	production	NN
cord-347298-7kqrl3rv	947	31	(	(	-LRB-
cord-347298-7kqrl3rv	947	32	Jarow	Jarow	NNP
cord-347298-7kqrl3rv	947	33	2001	2001	CD
cord-347298-7kqrl3rv	947	34	)	)	-RRB-
cord-347298-7kqrl3rv	947	35	.	.	.
cord-347298-7kqrl3rv	948	1	The	the	DT
cord-347298-7kqrl3rv	948	2	deleterious	deleterious	JJ
cord-347298-7kqrl3rv	948	3	effects	effect	NNS
cord-347298-7kqrl3rv	948	4	of	of	IN
cord-347298-7kqrl3rv	948	5	cadmium	cadmium	NN
cord-347298-7kqrl3rv	948	6	on	on	IN
cord-347298-7kqrl3rv	948	7	fertility	fertility	NN
cord-347298-7kqrl3rv	948	8	through	through	IN
cord-347298-7kqrl3rv	948	9	disruption	disruption	NN
cord-347298-7kqrl3rv	948	10	of	of	IN
cord-347298-7kqrl3rv	948	11	the	the	DT
cord-347298-7kqrl3rv	948	12	testicular	testicular	NN
cord-347298-7kqrl3rv	948	13	vasculature	vasculature	NN
cord-347298-7kqrl3rv	948	14	are	be	VBP
cord-347298-7kqrl3rv	948	15	well	well	RB
cord-347298-7kqrl3rv	948	16	known	know	VBN
cord-347298-7kqrl3rv	948	17	(	(	-LRB-
cord-347298-7kqrl3rv	948	18	Schrag	Schrag	NNP
cord-347298-7kqrl3rv	948	19	and	and	CC
cord-347298-7kqrl3rv	948	20	Dixon	Dixon	NNP
cord-347298-7kqrl3rv	948	21	1985	1985	CD
cord-347298-7kqrl3rv	948	22	)	)	-RRB-
cord-347298-7kqrl3rv	948	23	.	.	.
cord-347298-7kqrl3rv	949	1	In	in	IN
cord-347298-7kqrl3rv	949	2	experimental	experimental	JJ
cord-347298-7kqrl3rv	949	3	animals	animal	NNS
cord-347298-7kqrl3rv	949	4	,	,	,
cord-347298-7kqrl3rv	949	5	transient	transient	JJ
cord-347298-7kqrl3rv	949	6	torsion	torsion	NN
cord-347298-7kqrl3rv	949	7	of	of	IN
cord-347298-7kqrl3rv	949	8	the	the	DT
cord-347298-7kqrl3rv	949	9	spermatic	spermatic	JJ
cord-347298-7kqrl3rv	949	10	cord	cord	NN
cord-347298-7kqrl3rv	949	11	that	that	WDT
cord-347298-7kqrl3rv	949	12	renders	render	VBZ
cord-347298-7kqrl3rv	949	13	the	the	DT
cord-347298-7kqrl3rv	949	14	testis	testis	NN
cord-347298-7kqrl3rv	949	15	ischemic	ischemic	NN
cord-347298-7kqrl3rv	949	16	followed	follow	VBD
cord-347298-7kqrl3rv	949	17	by	by	IN
cord-347298-7kqrl3rv	949	18	reperfusion	reperfusion	NN
cord-347298-7kqrl3rv	949	19	causes	cause	VBZ
cord-347298-7kqrl3rv	949	20	an	an	DT
cord-347298-7kqrl3rv	949	21	increase	increase	NN
cord-347298-7kqrl3rv	949	22	in	in	IN
cord-347298-7kqrl3rv	949	23	TNF	TNF	NNP
cord-347298-7kqrl3rv	949	24	and	and	CC
cord-347298-7kqrl3rv	949	25	IL1	IL1	NNP
cord-347298-7kqrl3rv	949	26	expression	expression	NN
cord-347298-7kqrl3rv	949	27	,	,	,
cord-347298-7kqrl3rv	949	28	activation	activation	NN
cord-347298-7kqrl3rv	949	29	of	of	IN
cord-347298-7kqrl3rv	949	30	the	the	DT
cord-347298-7kqrl3rv	949	31	stress	stress	NN
cord-347298-7kqrl3rv	949	32	-	-	HYPH
cord-347298-7kqrl3rv	949	33	related	relate	VBN
cord-347298-7kqrl3rv	949	34	Jnk	Jnk	NNP
cord-347298-7kqrl3rv	949	35	/	/	SYM
cord-347298-7kqrl3rv	949	36	p38	p38	CD
cord-347298-7kqrl3rv	949	37	MAP	MAP	NNP
cord-347298-7kqrl3rv	949	38	kinase	kinase	NN
cord-347298-7kqrl3rv	949	39	signaling	signal	VBG
cord-347298-7kqrl3rv	949	40	pathway	pathway	NN
cord-347298-7kqrl3rv	949	41	,	,	,
cord-347298-7kqrl3rv	949	42	neutrophil	neutrophil	NN
cord-347298-7kqrl3rv	949	43	recruitment	recruitment	NN
cord-347298-7kqrl3rv	949	44	and	and	CC
cord-347298-7kqrl3rv	949	45	infiltration	infiltration	NN
cord-347298-7kqrl3rv	949	46	into	into	IN
cord-347298-7kqrl3rv	949	47	the	the	DT
cord-347298-7kqrl3rv	949	48	testis	testis	NN
cord-347298-7kqrl3rv	949	49	,	,	,
cord-347298-7kqrl3rv	949	50	increased	increase	VBD
cord-347298-7kqrl3rv	949	51	oxidative	oxidative	JJ
cord-347298-7kqrl3rv	949	52	stress	stress	NN
cord-347298-7kqrl3rv	949	53	,	,	,
cord-347298-7kqrl3rv	949	54	germ	germ	NN
cord-347298-7kqrl3rv	949	55	cell	cell	NN
cord-347298-7kqrl3rv	949	56	apoptosis	apoptosis	NN
cord-347298-7kqrl3rv	949	57	,	,	,
cord-347298-7kqrl3rv	949	58	and	and	CC
cord-347298-7kqrl3rv	949	59	significantly	significantly	RB
cord-347298-7kqrl3rv	949	60	decreased	decrease	VBD
cord-347298-7kqrl3rv	949	61	serum	serum	NN
cord-347298-7kqrl3rv	949	62	testosterone	testosterone	NN
cord-347298-7kqrl3rv	949	63	levels	level	NNS
cord-347298-7kqrl3rv	949	64	(	(	-LRB-
cord-347298-7kqrl3rv	949	65	Lysiak	Lysiak	NNP
cord-347298-7kqrl3rv	949	66	2004	2004	CD
cord-347298-7kqrl3rv	949	67	;	;	:
cord-347298-7kqrl3rv	949	68	Lysiak	Lysiak	NNP
cord-347298-7kqrl3rv	949	69	et	et	FW
cord-347298-7kqrl3rv	949	70	al	al	NNP
cord-347298-7kqrl3rv	949	71	.	.	NNP
cord-347298-7kqrl3rv	949	72	2001	2001	CD
cord-347298-7kqrl3rv	949	73	;	;	:
cord-347298-7kqrl3rv	949	74	Rodriguez	Rodriguez	NNP
cord-347298-7kqrl3rv	949	75	et	et	NNP
cord-347298-7kqrl3rv	949	76	al	al	NNP
cord-347298-7kqrl3rv	949	77	.	.	.
cord-347298-7kqrl3rv	949	78	2006	2006	CD
cord-347298-7kqrl3rv	949	79	)	)	-RRB-
cord-347298-7kqrl3rv	949	80	.	.	.
cord-347298-7kqrl3rv	950	1	A	a	DT
cord-347298-7kqrl3rv	950	2	specific	specific	JJ
cord-347298-7kqrl3rv	950	3	role	role	NN
cord-347298-7kqrl3rv	950	4	for	for	IN
cord-347298-7kqrl3rv	950	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	950	6	nitric	nitric	NN
cord-347298-7kqrl3rv	950	7	oxide	oxide	NN
cord-347298-7kqrl3rv	950	8	in	in	IN
cord-347298-7kqrl3rv	950	9	mediating	mediate	VBG
cord-347298-7kqrl3rv	950	10	damage	damage	NN
cord-347298-7kqrl3rv	950	11	in	in	IN
cord-347298-7kqrl3rv	950	12	both	both	CC
cord-347298-7kqrl3rv	950	13	the	the	DT
cord-347298-7kqrl3rv	950	14	testicular	testicular	JJ
cord-347298-7kqrl3rv	950	15	torsion	torsion	NN
cord-347298-7kqrl3rv	950	16	and	and	CC
cord-347298-7kqrl3rv	950	17	human	human	JJ
cord-347298-7kqrl3rv	950	18	varicocele	varicocele	NN
cord-347298-7kqrl3rv	950	19	models	model	NNS
cord-347298-7kqrl3rv	950	20	has	have	VBZ
cord-347298-7kqrl3rv	950	21	been	be	VBN
cord-347298-7kqrl3rv	950	22	implicated	implicate	VBN
cord-347298-7kqrl3rv	951	1	(	(	-LRB-
cord-347298-7kqrl3rv	951	2	Moon	Moon	NNP
cord-347298-7kqrl3rv	951	3	et	et	NNP
cord-347298-7kqrl3rv	951	4	al	al	NNP
cord-347298-7kqrl3rv	951	5	.	.	.
cord-347298-7kqrl3rv	952	1	2005	2005	CD
cord-347298-7kqrl3rv	952	2	;	;	:
cord-347298-7kqrl3rv	952	3	Santoro	Santoro	NNP
cord-347298-7kqrl3rv	952	4	et	et	NNP
cord-347298-7kqrl3rv	952	5	al	al	NNP
cord-347298-7kqrl3rv	952	6	.	.	.
cord-347298-7kqrl3rv	953	1	2001	2001	CD
cord-347298-7kqrl3rv	953	2	;	;	:
cord-347298-7kqrl3rv	953	3	Shiraishi	Shiraishi	NNP
cord-347298-7kqrl3rv	953	4	and	and	CC
cord-347298-7kqrl3rv	953	5	Naito	Naito	NNP
cord-347298-7kqrl3rv	953	6	2007	2007	CD
cord-347298-7kqrl3rv	953	7	;	;	:
cord-347298-7kqrl3rv	953	8	Shiraishi	Shiraishi	NNP
cord-347298-7kqrl3rv	953	9	et	et	NNP
cord-347298-7kqrl3rv	953	10	al	al	NNP
cord-347298-7kqrl3rv	953	11	.	.	.
cord-347298-7kqrl3rv	954	1	2001	2001	CD
cord-347298-7kqrl3rv	954	2	;	;	:
cord-347298-7kqrl3rv	954	3	Türker	Türker	NNP
cord-347298-7kqrl3rv	954	4	Köksal	Köksal	NNP
cord-347298-7kqrl3rv	954	5	et	et	NNP
cord-347298-7kqrl3rv	954	6	al	al	NNP
cord-347298-7kqrl3rv	954	7	.	.	.
cord-347298-7kqrl3rv	954	8	2004	2004	CD
cord-347298-7kqrl3rv	954	9	)	)	-RRB-
cord-347298-7kqrl3rv	954	10	.	.	.
cord-347298-7kqrl3rv	955	1	Administration	administration	NN
cord-347298-7kqrl3rv	955	2	of	of	IN
cord-347298-7kqrl3rv	955	3	high	high	JJ
cord-347298-7kqrl3rv	955	4	doses	dose	NNS
cord-347298-7kqrl3rv	955	5	of	of	IN
cord-347298-7kqrl3rv	955	6	human	human	JJ
cord-347298-7kqrl3rv	955	7	chorionic	chorionic	JJ
cord-347298-7kqrl3rv	955	8	gonadotropin	gonadotropin	NN
cord-347298-7kqrl3rv	955	9	(	(	-LRB-
cord-347298-7kqrl3rv	955	10	hCG	hCG	NNP
cord-347298-7kqrl3rv	955	11	)	)	-RRB-
cord-347298-7kqrl3rv	955	12	,	,	,
cord-347298-7kqrl3rv	955	13	a	a	DT
cord-347298-7kqrl3rv	955	14	treatment	treatment	NN
cord-347298-7kqrl3rv	955	15	used	use	VBN
cord-347298-7kqrl3rv	955	16	to	to	TO
cord-347298-7kqrl3rv	955	17	correct	correct	VB
cord-347298-7kqrl3rv	955	18	delayed	delay	VBN
cord-347298-7kqrl3rv	955	19	testicular	testicular	JJ
cord-347298-7kqrl3rv	955	20	descent	descent	NN
cord-347298-7kqrl3rv	955	21	in	in	IN
cord-347298-7kqrl3rv	955	22	young	young	JJ
cord-347298-7kqrl3rv	955	23	boys	boy	NNS
cord-347298-7kqrl3rv	955	24	,	,	,
cord-347298-7kqrl3rv	955	25	causes	cause	VBZ
cord-347298-7kqrl3rv	955	26	a	a	DT
cord-347298-7kqrl3rv	955	27	hyperstimulation	hyperstimulation	NN
cord-347298-7kqrl3rv	955	28	syndrome	syndrome	NN
cord-347298-7kqrl3rv	955	29	in	in	IN
cord-347298-7kqrl3rv	955	30	rats	rat	NNS
cord-347298-7kqrl3rv	955	31	comprising	comprise	VBG
cord-347298-7kqrl3rv	955	32	increased	increase	VBN
cord-347298-7kqrl3rv	955	33	testicular	testicular	JJ
cord-347298-7kqrl3rv	955	34	blood	blood	NN
cord-347298-7kqrl3rv	955	35	flow	flow	NN
cord-347298-7kqrl3rv	955	36	and	and	CC
cord-347298-7kqrl3rv	955	37	pressure	pressure	NN
cord-347298-7kqrl3rv	955	38	,	,	,
cord-347298-7kqrl3rv	955	39	increased	increase	VBD
cord-347298-7kqrl3rv	955	40	vascular	vascular	JJ
cord-347298-7kqrl3rv	955	41	permeability	permeability	NN
cord-347298-7kqrl3rv	955	42	,	,	,
cord-347298-7kqrl3rv	955	43	and	and	CC
cord-347298-7kqrl3rv	955	44	accumulation	accumulation	NN
cord-347298-7kqrl3rv	955	45	of	of	IN
cord-347298-7kqrl3rv	955	46	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	955	47	fluid	fluid	NN
cord-347298-7kqrl3rv	955	48	(	(	-LRB-
cord-347298-7kqrl3rv	955	49	Hjertkvist	Hjertkvist	NNP
cord-347298-7kqrl3rv	955	50	et	et	FW
cord-347298-7kqrl3rv	955	51	al	al	NNP
cord-347298-7kqrl3rv	955	52	.	.	.
cord-347298-7kqrl3rv	955	53	1993	1993	CD
cord-347298-7kqrl3rv	955	54	;	;	:
cord-347298-7kqrl3rv	955	55	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	955	56	and	and	CC
cord-347298-7kqrl3rv	955	57	Sharpe	Sharpe	NNP
cord-347298-7kqrl3rv	955	58	1981	1981	CD
cord-347298-7kqrl3rv	955	59	;	;	:
cord-347298-7kqrl3rv	956	1	van	van	NNP
cord-347298-7kqrl3rv	956	2	Vliet	Vliet	NNP
cord-347298-7kqrl3rv	956	3	et	et	NNP
cord-347298-7kqrl3rv	956	4	al	al	NNP
cord-347298-7kqrl3rv	956	5	.	.	.
cord-347298-7kqrl3rv	956	6	1988	1988	CD
cord-347298-7kqrl3rv	956	7	)	)	-RRB-
cord-347298-7kqrl3rv	956	8	.	.	.
cord-347298-7kqrl3rv	957	1	These	these	DT
cord-347298-7kqrl3rv	957	2	vascular	vascular	JJ
cord-347298-7kqrl3rv	957	3	changes	change	NNS
cord-347298-7kqrl3rv	957	4	are	be	VBP
cord-347298-7kqrl3rv	957	5	accompanied	accompany	VBN
cord-347298-7kqrl3rv	957	6	by	by	IN
cord-347298-7kqrl3rv	957	7	accumulation	accumulation	NN
cord-347298-7kqrl3rv	957	8	of	of	IN
cord-347298-7kqrl3rv	957	9	intravascular	intravascular	JJ
cord-347298-7kqrl3rv	957	10	and	and	CC
cord-347298-7kqrl3rv	957	11	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	957	12	neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	957	13	in	in	IN
cord-347298-7kqrl3rv	957	14	the	the	DT
cord-347298-7kqrl3rv	957	15	testis	testis	NN
cord-347298-7kqrl3rv	958	1	(	(	-LRB-
cord-347298-7kqrl3rv	958	2	Bergh	Bergh	NNP
cord-347298-7kqrl3rv	958	3	et	et	NNP
cord-347298-7kqrl3rv	958	4	al	al	NNP
cord-347298-7kqrl3rv	958	5	.	.	.
cord-347298-7kqrl3rv	958	6	1986	1986	CD
cord-347298-7kqrl3rv	958	7	;	;	:
cord-347298-7kqrl3rv	958	8	Widmark	Widmark	NNP
cord-347298-7kqrl3rv	958	9	et	et	NNP
cord-347298-7kqrl3rv	958	10	al	al	NNP
cord-347298-7kqrl3rv	958	11	.	.	NNP
cord-347298-7kqrl3rv	958	12	1987	1987	CD
cord-347298-7kqrl3rv	958	13	)	)	-RRB-
cord-347298-7kqrl3rv	958	14	,	,	,
cord-347298-7kqrl3rv	958	15	and	and	CC
cord-347298-7kqrl3rv	958	16	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	958	17	damage	damage	NN
cord-347298-7kqrl3rv	959	1	(	(	-LRB-
cord-347298-7kqrl3rv	959	2	Kerr	Kerr	NNP
cord-347298-7kqrl3rv	959	3	and	and	CC
cord-347298-7kqrl3rv	959	4	Sharpe	Sharpe	NNP
cord-347298-7kqrl3rv	959	5	1989a	1989a	NNS
cord-347298-7kqrl3rv	959	6	,	,	,
cord-347298-7kqrl3rv	959	7	b	b	LS
cord-347298-7kqrl3rv	959	8	)	)	-RRB-
cord-347298-7kqrl3rv	959	9	.	.	.
cord-347298-7kqrl3rv	960	1	The	the	DT
cord-347298-7kqrl3rv	960	2	responses	response	NNS
cord-347298-7kqrl3rv	960	3	to	to	IN
cord-347298-7kqrl3rv	960	4	hCG	hCG	NNP
cord-347298-7kqrl3rv	960	5	can	can	MD
cord-347298-7kqrl3rv	960	6	be	be	VB
cord-347298-7kqrl3rv	960	7	eliminated	eliminate	VBN
cord-347298-7kqrl3rv	960	8	by	by	IN
cord-347298-7kqrl3rv	960	9	depletion	depletion	NN
cord-347298-7kqrl3rv	960	10	of	of	IN
cord-347298-7kqrl3rv	960	11	either	either	CC
cord-347298-7kqrl3rv	960	12	the	the	DT
cord-347298-7kqrl3rv	960	13	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	960	14	cells	cell	NNS
cord-347298-7kqrl3rv	960	15	or	or	CC
cord-347298-7kqrl3rv	960	16	the	the	DT
cord-347298-7kqrl3rv	960	17	neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	960	18	(	(	-LRB-
cord-347298-7kqrl3rv	960	19	Setchell	Setchell	NNP
cord-347298-7kqrl3rv	960	20	and	and	CC
cord-347298-7kqrl3rv	960	21	Rommerts	Rommerts	NNP
cord-347298-7kqrl3rv	960	22	1985	1985	CD
cord-347298-7kqrl3rv	960	23	;	;	:
cord-347298-7kqrl3rv	960	24	Widmark	Widmark	NNP
cord-347298-7kqrl3rv	960	25	et	et	NNP
cord-347298-7kqrl3rv	960	26	al	al	NNP
cord-347298-7kqrl3rv	960	27	.	.	NNP
cord-347298-7kqrl3rv	960	28	1987	1987	CD
cord-347298-7kqrl3rv	960	29	)	)	-RRB-
cord-347298-7kqrl3rv	960	30	,	,	,
cord-347298-7kqrl3rv	960	31	and	and	CC
cord-347298-7kqrl3rv	960	32	IL1	IL1	NNP
cord-347298-7kqrl3rv	960	33	is	be	VBZ
cord-347298-7kqrl3rv	960	34	able	able	JJ
cord-347298-7kqrl3rv	960	35	to	to	TO
cord-347298-7kqrl3rv	960	36	replicate	replicate	VB
cord-347298-7kqrl3rv	960	37	most	most	JJS
cord-347298-7kqrl3rv	960	38	of	of	IN
cord-347298-7kqrl3rv	960	39	the	the	DT
cord-347298-7kqrl3rv	960	40	effects	effect	NNS
cord-347298-7kqrl3rv	960	41	(	(	-LRB-
cord-347298-7kqrl3rv	960	42	Bergh	Bergh	NNP
cord-347298-7kqrl3rv	960	43	and	and	CC
cord-347298-7kqrl3rv	960	44	Söder	Söder	NNP
cord-347298-7kqrl3rv	960	45	1990	1990	CD
cord-347298-7kqrl3rv	960	46	;	;	:
cord-347298-7kqrl3rv	960	47	Bergh	Bergh	NNP
cord-347298-7kqrl3rv	960	48	et	et	NNP
cord-347298-7kqrl3rv	960	49	al	al	NNP
cord-347298-7kqrl3rv	960	50	.	.	.
cord-347298-7kqrl3rv	960	51	1996	1996	CD
cord-347298-7kqrl3rv	960	52	)	)	-RRB-
cord-347298-7kqrl3rv	960	53	,	,	,
cord-347298-7kqrl3rv	960	54	suggesting	suggest	VBG
cord-347298-7kqrl3rv	960	55	that	that	IN
cord-347298-7kqrl3rv	960	56	the	the	DT
cord-347298-7kqrl3rv	960	57	response	response	NN
cord-347298-7kqrl3rv	960	58	involves	involve	VBZ
cord-347298-7kqrl3rv	960	59	an	an	DT
cord-347298-7kqrl3rv	960	60	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	960	61	event	event	NN
cord-347298-7kqrl3rv	960	62	mediated	mediate	VBN
cord-347298-7kqrl3rv	960	63	via	via	IN
cord-347298-7kqrl3rv	960	64	IL1	IL1	NNP
cord-347298-7kqrl3rv	960	65	secreted	secrete	VBN
cord-347298-7kqrl3rv	960	66	by	by	IN
cord-347298-7kqrl3rv	960	67	the	the	DT
cord-347298-7kqrl3rv	960	68	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	960	69	cells	cell	NNS
cord-347298-7kqrl3rv	960	70	.	.	.
cord-347298-7kqrl3rv	961	1	Thus	thus	RB
cord-347298-7kqrl3rv	961	2	,	,	,
cord-347298-7kqrl3rv	961	3	it	-PRON-	PRP
cord-347298-7kqrl3rv	961	4	appears	appear	VBZ
cord-347298-7kqrl3rv	961	5	that	that	IN
cord-347298-7kqrl3rv	961	6	disruption	disruption	NN
cord-347298-7kqrl3rv	961	7	of	of	IN
cord-347298-7kqrl3rv	961	8	the	the	DT
cord-347298-7kqrl3rv	961	9	seminiferous	seminiferous	JJ
cord-347298-7kqrl3rv	961	10	epithelium	epithelium	NN
cord-347298-7kqrl3rv	961	11	in	in	IN
cord-347298-7kqrl3rv	961	12	both	both	CC
cord-347298-7kqrl3rv	961	13	the	the	DT
cord-347298-7kqrl3rv	961	14	ischemia	ischemia	NN
cord-347298-7kqrl3rv	961	15	/	/	SYM
cord-347298-7kqrl3rv	961	16	reperfusion	reperfusion	NN
cord-347298-7kqrl3rv	961	17	model	model	NN
cord-347298-7kqrl3rv	961	18	and	and	CC
cord-347298-7kqrl3rv	961	19	hCG	hcg	NN
cord-347298-7kqrl3rv	961	20	hyperstimulation	hyperstimulation	NN
cord-347298-7kqrl3rv	961	21	models	model	NNS
cord-347298-7kqrl3rv	961	22	is	be	VBZ
cord-347298-7kqrl3rv	961	23	directly	directly	RB
cord-347298-7kqrl3rv	961	24	linked	link	VBN
cord-347298-7kqrl3rv	961	25	to	to	IN
cord-347298-7kqrl3rv	961	26	local	local	JJ
cord-347298-7kqrl3rv	961	27	recruitment	recruitment	NN
cord-347298-7kqrl3rv	961	28	of	of	IN
cord-347298-7kqrl3rv	961	29	neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	961	30	.	.	.
cord-347298-7kqrl3rv	962	1	Exactly	exactly	RB
cord-347298-7kqrl3rv	962	2	how	how	WRB
cord-347298-7kqrl3rv	962	3	these	these	DT
cord-347298-7kqrl3rv	962	4	cells	cell	NNS
cord-347298-7kqrl3rv	962	5	exert	exert	VBP
cord-347298-7kqrl3rv	962	6	damage	damage	NN
cord-347298-7kqrl3rv	962	7	on	on	IN
cord-347298-7kqrl3rv	962	8	the	the	DT
cord-347298-7kqrl3rv	962	9	germ	germ	NN
cord-347298-7kqrl3rv	962	10	cells	cell	NNS
cord-347298-7kqrl3rv	962	11	is	be	VBZ
cord-347298-7kqrl3rv	962	12	not	not	RB
cord-347298-7kqrl3rv	962	13	yet	yet	RB
cord-347298-7kqrl3rv	962	14	known	know	VBN
cord-347298-7kqrl3rv	962	15	,	,	,
cord-347298-7kqrl3rv	962	16	but	but	CC
cord-347298-7kqrl3rv	962	17	increased	increase	VBN
cord-347298-7kqrl3rv	962	18	oxidative	oxidative	JJ
cord-347298-7kqrl3rv	962	19	stress	stress	NN
cord-347298-7kqrl3rv	962	20	is	be	VBZ
cord-347298-7kqrl3rv	962	21	obviously	obviously	RB
cord-347298-7kqrl3rv	962	22	involved	involved	JJ
cord-347298-7kqrl3rv	962	23	.	.	.
cord-347298-7kqrl3rv	963	1	The	the	DT
cord-347298-7kqrl3rv	963	2	responses	response	NNS
cord-347298-7kqrl3rv	963	3	are	be	VBP
cord-347298-7kqrl3rv	963	4	quite	quite	RB
cord-347298-7kqrl3rv	963	5	different	different	JJ
cord-347298-7kqrl3rv	963	6	from	from	IN
cord-347298-7kqrl3rv	963	7	those	those	DT
cord-347298-7kqrl3rv	963	8	observed	observe	VBN
cord-347298-7kqrl3rv	963	9	in	in	IN
cord-347298-7kqrl3rv	963	10	LPS	LPS	NNP
cord-347298-7kqrl3rv	963	11	-	-	HYPH
cord-347298-7kqrl3rv	963	12	induced	induce	VBN
cord-347298-7kqrl3rv	963	13	inflammation	inflammation	NN
cord-347298-7kqrl3rv	963	14	,	,	,
cord-347298-7kqrl3rv	963	15	which	which	WDT
cord-347298-7kqrl3rv	963	16	paradoxically	paradoxically	RB
cord-347298-7kqrl3rv	963	17	causes	cause	VBZ
cord-347298-7kqrl3rv	963	18	a	a	DT
cord-347298-7kqrl3rv	963	19	large	large	JJ
cord-347298-7kqrl3rv	963	20	reduction	reduction	NN
cord-347298-7kqrl3rv	963	21	in	in	IN
cord-347298-7kqrl3rv	963	22	interstitial	interstitial	JJ
cord-347298-7kqrl3rv	963	23	fluid	fluid	JJ
cord-347298-7kqrl3rv	963	24	volume	volume	NN
cord-347298-7kqrl3rv	963	25	and	and	CC
cord-347298-7kqrl3rv	963	26	an	an	DT
cord-347298-7kqrl3rv	963	27	increase	increase	NN
cord-347298-7kqrl3rv	963	28	in	in	IN
cord-347298-7kqrl3rv	963	29	mononuclear	mononuclear	JJ
cord-347298-7kqrl3rv	963	30	cells	cell	NNS
cord-347298-7kqrl3rv	963	31	in	in	IN
cord-347298-7kqrl3rv	963	32	the	the	DT
cord-347298-7kqrl3rv	963	33	rat	rat	NN
cord-347298-7kqrl3rv	963	34	testis	testis	NN
cord-347298-7kqrl3rv	963	35	(	(	-LRB-
cord-347298-7kqrl3rv	963	36	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	963	37	et	et	NNP
cord-347298-7kqrl3rv	963	38	al	al	NNP
cord-347298-7kqrl3rv	963	39	.	.	.
cord-347298-7kqrl3rv	964	1	2000b	2000b	LS
cord-347298-7kqrl3rv	964	2	;	;	:
cord-347298-7kqrl3rv	964	3	Gerdprasert	Gerdprasert	NNP
cord-347298-7kqrl3rv	964	4	et	et	NNP
cord-347298-7kqrl3rv	964	5	al	al	NNP
cord-347298-7kqrl3rv	964	6	.	.	.
cord-347298-7kqrl3rv	965	1	2002a	2002a	CD
cord-347298-7kqrl3rv	965	2	,	,	,
cord-347298-7kqrl3rv	965	3	b	b	LS
cord-347298-7kqrl3rv	965	4	)	)	-RRB-
cord-347298-7kqrl3rv	965	5	,	,	,
cord-347298-7kqrl3rv	965	6	although	although	IN
cord-347298-7kqrl3rv	965	7	the	the	DT
cord-347298-7kqrl3rv	965	8	germ	germ	NN
cord-347298-7kqrl3rv	965	9	cell	cell	NN
cord-347298-7kqrl3rv	965	10	damage	damage	NN
cord-347298-7kqrl3rv	965	11	is	be	VBZ
cord-347298-7kqrl3rv	965	12	similar	similar	JJ
cord-347298-7kqrl3rv	965	13	in	in	IN
cord-347298-7kqrl3rv	965	14	both	both	DT
cord-347298-7kqrl3rv	965	15	models	model	NNS
cord-347298-7kqrl3rv	965	16	.	.	.
cord-347298-7kqrl3rv	966	1	In	in	IN
cord-347298-7kqrl3rv	966	2	summary	summary	NN
cord-347298-7kqrl3rv	966	3	,	,	,
cord-347298-7kqrl3rv	966	4	different	different	JJ
cord-347298-7kqrl3rv	966	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	966	6	inflammation	inflammation	NN
cord-347298-7kqrl3rv	966	7	models	model	NNS
cord-347298-7kqrl3rv	966	8	have	have	VBP
cord-347298-7kqrl3rv	966	9	direct	direct	JJ
cord-347298-7kqrl3rv	966	10	effects	effect	NNS
cord-347298-7kqrl3rv	966	11	on	on	IN
cord-347298-7kqrl3rv	966	12	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	966	13	development	development	NN
cord-347298-7kqrl3rv	966	14	,	,	,
cord-347298-7kqrl3rv	966	15	in	in	IN
cord-347298-7kqrl3rv	966	16	addition	addition	NN
cord-347298-7kqrl3rv	966	17	to	to	IN
cord-347298-7kqrl3rv	966	18	causing	cause	VBG
cord-347298-7kqrl3rv	966	19	damage	damage	NN
cord-347298-7kqrl3rv	966	20	to	to	IN
cord-347298-7kqrl3rv	966	21	the	the	DT
cord-347298-7kqrl3rv	966	22	steroiodogenic	steroiodogenic	JJ
cord-347298-7kqrl3rv	966	23	function	function	NN
cord-347298-7kqrl3rv	966	24	of	of	IN
cord-347298-7kqrl3rv	966	25	the	the	DT
cord-347298-7kqrl3rv	966	26	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	966	27	cells	cell	NNS
cord-347298-7kqrl3rv	966	28	.	.	.
cord-347298-7kqrl3rv	967	1	It	-PRON-	PRP
cord-347298-7kqrl3rv	967	2	should	should	MD
cord-347298-7kqrl3rv	967	3	also	also	RB
cord-347298-7kqrl3rv	967	4	be	be	VB
cord-347298-7kqrl3rv	967	5	noted	note	VBN
cord-347298-7kqrl3rv	967	6	that	that	IN
cord-347298-7kqrl3rv	967	7	,	,	,
cord-347298-7kqrl3rv	967	8	as	as	IN
cord-347298-7kqrl3rv	967	9	in	in	IN
cord-347298-7kqrl3rv	967	10	most	most	JJS
cord-347298-7kqrl3rv	967	11	other	other	JJ
cord-347298-7kqrl3rv	967	12	tissues	tissue	NNS
cord-347298-7kqrl3rv	967	13	,	,	,
cord-347298-7kqrl3rv	967	14	inflammation	inflammation	NN
cord-347298-7kqrl3rv	967	15	responses	response	NNS
cord-347298-7kqrl3rv	967	16	within	within	IN
cord-347298-7kqrl3rv	967	17	the	the	DT
cord-347298-7kqrl3rv	967	18	testis	testis	NN
cord-347298-7kqrl3rv	967	19	do	do	VBP
cord-347298-7kqrl3rv	967	20	not	not	RB
cord-347298-7kqrl3rv	967	21	automatically	automatically	RB
cord-347298-7kqrl3rv	967	22	lead	lead	VB
cord-347298-7kqrl3rv	967	23	to	to	IN
cord-347298-7kqrl3rv	967	24	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	967	25	complications	complication	NNS
cord-347298-7kqrl3rv	967	26	,	,	,
cord-347298-7kqrl3rv	967	27	but	but	CC
cord-347298-7kqrl3rv	967	28	damage	damage	NN
cord-347298-7kqrl3rv	967	29	to	to	IN
cord-347298-7kqrl3rv	967	30	various	various	JJ
cord-347298-7kqrl3rv	967	31	testicular	testicular	JJ
cord-347298-7kqrl3rv	967	32	functions	function	NNS
cord-347298-7kqrl3rv	967	33	that	that	WDT
cord-347298-7kqrl3rv	967	34	may	may	MD
cord-347298-7kqrl3rv	967	35	be	be	VB
cord-347298-7kqrl3rv	967	36	less	less	RBR
cord-347298-7kqrl3rv	967	37	readily	readily	RB
cord-347298-7kqrl3rv	967	38	apparent	apparent	JJ
cord-347298-7kqrl3rv	967	39	may	may	MD
cord-347298-7kqrl3rv	967	40	lead	lead	VB
cord-347298-7kqrl3rv	967	41	to	to	IN
cord-347298-7kqrl3rv	967	42	longer	long	JJR
cord-347298-7kqrl3rv	967	43	-	-	HYPH
cord-347298-7kqrl3rv	967	44	term	term	NN
cord-347298-7kqrl3rv	967	45	consequences	consequence	NNS
cord-347298-7kqrl3rv	967	46	for	for	IN
cord-347298-7kqrl3rv	967	47	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	967	48	health	health	NN
cord-347298-7kqrl3rv	967	49	(	(	-LRB-
cord-347298-7kqrl3rv	967	50	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	967	51	and	and	CC
cord-347298-7kqrl3rv	967	52	Meinhardt	Meinhardt	NNP
cord-347298-7kqrl3rv	967	53	2005	2005	CD
cord-347298-7kqrl3rv	967	54	;	;	:
cord-347298-7kqrl3rv	967	55	Schuppe	Schuppe	NNP
cord-347298-7kqrl3rv	967	56	et	et	NNP
cord-347298-7kqrl3rv	967	57	al	al	NNP
cord-347298-7kqrl3rv	967	58	.	.	NNP
cord-347298-7kqrl3rv	967	59	2008	2008	CD
cord-347298-7kqrl3rv	967	60	;	;	.
cord-347298-7kqrl3rv	968	1	Suominen	Suominen	NNP
cord-347298-7kqrl3rv	968	2	and	and	CC
cord-347298-7kqrl3rv	968	3	Soderstrom	Soderstrom	NNP
cord-347298-7kqrl3rv	968	4	1982	1982	CD
cord-347298-7kqrl3rv	968	5	)	)	-RRB-
cord-347298-7kqrl3rv	968	6	.	.	.
cord-347298-7kqrl3rv	969	1	11.10.4.5	11.10.4.5	CD
cord-347298-7kqrl3rv	970	1	The	the	DT
cord-347298-7kqrl3rv	970	2	Epididymis	Epididymis	NNP
cord-347298-7kqrl3rv	970	3	,	,	,
cord-347298-7kqrl3rv	970	4	Vas	Vas	NNP
cord-347298-7kqrl3rv	970	5	Deferens	Deferens	NNP
cord-347298-7kqrl3rv	970	6	,	,	,
cord-347298-7kqrl3rv	970	7	Accessory	accessory	JJ
cord-347298-7kqrl3rv	970	8	Glands	gland	NNS
cord-347298-7kqrl3rv	970	9	,	,	,
cord-347298-7kqrl3rv	970	10	and	and	CC
cord-347298-7kqrl3rv	970	11	Urogenital	Urogenital	NNP
cord-347298-7kqrl3rv	970	12	Tract	Tract	NNP
cord-347298-7kqrl3rv	971	1	As	as	IN
cord-347298-7kqrl3rv	971	2	already	already	RB
cord-347298-7kqrl3rv	971	3	noted	note	VBN
cord-347298-7kqrl3rv	971	4	above	above	RB
cord-347298-7kqrl3rv	971	5	,	,	,
cord-347298-7kqrl3rv	971	6	the	the	DT
cord-347298-7kqrl3rv	971	7	immune	immune	JJ
cord-347298-7kqrl3rv	971	8	environment	environment	NN
cord-347298-7kqrl3rv	971	9	of	of	IN
cord-347298-7kqrl3rv	971	10	the	the	DT
cord-347298-7kqrl3rv	971	11	remainder	remainder	NN
cord-347298-7kqrl3rv	971	12	of	of	IN
cord-347298-7kqrl3rv	971	13	the	the	DT
cord-347298-7kqrl3rv	971	14	male	male	JJ
cord-347298-7kqrl3rv	971	15	tract	tract	NN
cord-347298-7kqrl3rv	971	16	is	be	VBZ
cord-347298-7kqrl3rv	971	17	quite	quite	RB
cord-347298-7kqrl3rv	971	18	distinct	distinct	JJ
cord-347298-7kqrl3rv	971	19	from	from	IN
cord-347298-7kqrl3rv	971	20	that	that	DT
cord-347298-7kqrl3rv	971	21	of	of	IN
cord-347298-7kqrl3rv	971	22	the	the	DT
cord-347298-7kqrl3rv	971	23	testis	testis	NN
cord-347298-7kqrl3rv	971	24	,	,	,
cord-347298-7kqrl3rv	971	25	or	or	CC
cord-347298-7kqrl3rv	971	26	even	even	RB
cord-347298-7kqrl3rv	971	27	from	from	IN
cord-347298-7kqrl3rv	971	28	that	that	DT
cord-347298-7kqrl3rv	971	29	of	of	IN
cord-347298-7kqrl3rv	971	30	other	other	JJ
cord-347298-7kqrl3rv	971	31	mucosal	mucosal	JJ
cord-347298-7kqrl3rv	971	32	tissues	tissue	NNS
cord-347298-7kqrl3rv	971	33	.	.	.
cord-347298-7kqrl3rv	972	1	The	the	DT
cord-347298-7kqrl3rv	972	2	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	972	3	whereby	whereby	WRB
cord-347298-7kqrl3rv	972	4	sperm	sperm	NN
cord-347298-7kqrl3rv	972	5	within	within	IN
cord-347298-7kqrl3rv	972	6	the	the	DT
cord-347298-7kqrl3rv	972	7	male	male	JJ
cord-347298-7kqrl3rv	972	8	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	972	9	tract	tract	NN
cord-347298-7kqrl3rv	972	10	are	be	VBP
cord-347298-7kqrl3rv	972	11	protected	protect	VBN
cord-347298-7kqrl3rv	972	12	from	from	IN
cord-347298-7kqrl3rv	972	13	the	the	DT
cord-347298-7kqrl3rv	972	14	immune	immune	JJ
cord-347298-7kqrl3rv	972	15	system	system	NN
cord-347298-7kqrl3rv	972	16	remain	remain	VBP
cord-347298-7kqrl3rv	972	17	largely	largely	RB
cord-347298-7kqrl3rv	972	18	unknown	unknown	JJ
cord-347298-7kqrl3rv	972	19	,	,	,
cord-347298-7kqrl3rv	972	20	but	but	CC
cord-347298-7kqrl3rv	972	21	an	an	DT
cord-347298-7kqrl3rv	972	22	intact	intact	JJ
cord-347298-7kqrl3rv	972	23	tract	tract	NN
cord-347298-7kqrl3rv	972	24	is	be	VBZ
cord-347298-7kqrl3rv	972	25	obviously	obviously	RB
cord-347298-7kqrl3rv	972	26	important	important	JJ
cord-347298-7kqrl3rv	972	27	.	.	.
cord-347298-7kqrl3rv	973	1	In	in	IN
cord-347298-7kqrl3rv	973	2	humans	human	NNS
cord-347298-7kqrl3rv	973	3	,	,	,
cord-347298-7kqrl3rv	973	4	vasectomy	vasectomy	NN
cord-347298-7kqrl3rv	973	5	leads	lead	VBZ
cord-347298-7kqrl3rv	973	6	to	to	TO
cord-347298-7kqrl3rv	973	7	sperm	sperm	VB
cord-347298-7kqrl3rv	973	8	antibody	antibody	NN
cord-347298-7kqrl3rv	973	9	formation	formation	NN
cord-347298-7kqrl3rv	973	10	in	in	IN
cord-347298-7kqrl3rv	973	11	approximately	approximately	RB
cord-347298-7kqrl3rv	973	12	70	70	CD
cord-347298-7kqrl3rv	973	13	%	%	NN
cord-347298-7kqrl3rv	973	14	of	of	IN
cord-347298-7kqrl3rv	973	15	cases	case	NNS
cord-347298-7kqrl3rv	973	16	,	,	,
cord-347298-7kqrl3rv	973	17	and	and	CC
cord-347298-7kqrl3rv	973	18	sperm	sperm	NN
cord-347298-7kqrl3rv	973	19	antibodies	antibody	NNS
cord-347298-7kqrl3rv	973	20	are	be	VBP
cord-347298-7kqrl3rv	973	21	also	also	RB
cord-347298-7kqrl3rv	973	22	associated	associate	VBN
cord-347298-7kqrl3rv	973	23	with	with	IN
cord-347298-7kqrl3rv	973	24	obstructive	obstructive	JJ
cord-347298-7kqrl3rv	973	25	azoospermia	azoospermia	NN
cord-347298-7kqrl3rv	973	26	and	and	CC
cord-347298-7kqrl3rv	973	27	congenital	congenital	JJ
cord-347298-7kqrl3rv	973	28	absence	absence	NN
cord-347298-7kqrl3rv	973	29	of	of	IN
cord-347298-7kqrl3rv	973	30	the	the	DT
cord-347298-7kqrl3rv	973	31	epididymis	epididymis	NN
cord-347298-7kqrl3rv	973	32	and/or	and/or	CC
cord-347298-7kqrl3rv	973	33	vas	vas	NNP
cord-347298-7kqrl3rv	973	34	(	(	-LRB-
cord-347298-7kqrl3rv	973	35	Alexander	Alexander	NNP
cord-347298-7kqrl3rv	973	36	and	and	CC
cord-347298-7kqrl3rv	973	37	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	973	38	1979	1979	CD
cord-347298-7kqrl3rv	973	39	;	;	:
cord-347298-7kqrl3rv	973	40	de	de	NNP
cord-347298-7kqrl3rv	973	41	Kretser	Kretser	NNP
cord-347298-7kqrl3rv	973	42	et	et	NNP
cord-347298-7kqrl3rv	973	43	al	al	NNP
cord-347298-7kqrl3rv	973	44	.	.	.
cord-347298-7kqrl3rv	974	1	1998	1998	CD
cord-347298-7kqrl3rv	974	2	;	;	:
cord-347298-7kqrl3rv	974	3	Hellema	Hellema	NNP
cord-347298-7kqrl3rv	974	4	et	et	NNP
cord-347298-7kqrl3rv	974	5	al	al	NNP
cord-347298-7kqrl3rv	974	6	.	.	.
cord-347298-7kqrl3rv	975	1	1979	1979	CD
cord-347298-7kqrl3rv	975	2	;	;	:
cord-347298-7kqrl3rv	975	3	Patrizio	Patrizio	NNP
cord-347298-7kqrl3rv	975	4	et	et	NNP
cord-347298-7kqrl3rv	975	5	al	al	NNP
cord-347298-7kqrl3rv	975	6	.	.	NNP
cord-347298-7kqrl3rv	975	7	1992	1992	CD
cord-347298-7kqrl3rv	975	8	)	)	-RRB-
cord-347298-7kqrl3rv	975	9	.	.	.
cord-347298-7kqrl3rv	976	1	The	the	DT
cord-347298-7kqrl3rv	976	2	incidence	incidence	NN
cord-347298-7kqrl3rv	976	3	of	of	IN
cord-347298-7kqrl3rv	976	4	antibody	antibody	NN
cord-347298-7kqrl3rv	976	5	formation	formation	NN
cord-347298-7kqrl3rv	976	6	in	in	IN
cord-347298-7kqrl3rv	976	7	humans	human	NNS
cord-347298-7kqrl3rv	976	8	appears	appear	VBZ
cord-347298-7kqrl3rv	976	9	to	to	TO
cord-347298-7kqrl3rv	976	10	be	be	VB
cord-347298-7kqrl3rv	976	11	directly	directly	RB
cord-347298-7kqrl3rv	976	12	related	relate	VBN
cord-347298-7kqrl3rv	976	13	to	to	IN
cord-347298-7kqrl3rv	976	14	the	the	DT
cord-347298-7kqrl3rv	976	15	distance	distance	NN
cord-347298-7kqrl3rv	976	16	of	of	IN
cord-347298-7kqrl3rv	976	17	the	the	DT
cord-347298-7kqrl3rv	976	18	lesion	lesion	NN
cord-347298-7kqrl3rv	976	19	from	from	IN
cord-347298-7kqrl3rv	976	20	the	the	DT
cord-347298-7kqrl3rv	976	21	testis	testis	NN
cord-347298-7kqrl3rv	976	22	,	,	,
cord-347298-7kqrl3rv	976	23	implying	imply	VBG
cord-347298-7kqrl3rv	976	24	a	a	DT
cord-347298-7kqrl3rv	976	25	limited	limited	JJ
cord-347298-7kqrl3rv	976	26	role	role	NN
cord-347298-7kqrl3rv	976	27	for	for	IN
cord-347298-7kqrl3rv	976	28	elements	element	NNS
cord-347298-7kqrl3rv	976	29	of	of	IN
cord-347298-7kqrl3rv	976	30	testicular	testicular	JJ
cord-347298-7kqrl3rv	976	31	immune	immune	JJ
cord-347298-7kqrl3rv	976	32	privilege	privilege	NN
cord-347298-7kqrl3rv	976	33	in	in	IN
cord-347298-7kqrl3rv	976	34	preventing	prevent	VBG
cord-347298-7kqrl3rv	976	35	immune	immune	JJ
cord-347298-7kqrl3rv	976	36	reactions	reaction	NNS
cord-347298-7kqrl3rv	976	37	.	.	.
cord-347298-7kqrl3rv	977	1	There	there	EX
cord-347298-7kqrl3rv	977	2	is	be	VBZ
cord-347298-7kqrl3rv	977	3	evidence	evidence	NN
cord-347298-7kqrl3rv	977	4	from	from	IN
cord-347298-7kqrl3rv	977	5	patients	patient	NNS
cord-347298-7kqrl3rv	977	6	and	and	CC
cord-347298-7kqrl3rv	977	7	animal	animal	NN
cord-347298-7kqrl3rv	977	8	models	model	NNS
cord-347298-7kqrl3rv	977	9	that	that	WDT
cord-347298-7kqrl3rv	977	10	vasectomy	vasectomy	NN
cord-347298-7kqrl3rv	977	11	can	can	MD
cord-347298-7kqrl3rv	977	12	have	have	VB
cord-347298-7kqrl3rv	977	13	deleterious	deleterious	JJ
cord-347298-7kqrl3rv	977	14	effects	effect	NNS
cord-347298-7kqrl3rv	977	15	on	on	IN
cord-347298-7kqrl3rv	977	16	the	the	DT
cord-347298-7kqrl3rv	977	17	testis	testis	NN
cord-347298-7kqrl3rv	977	18	and	and	CC
cord-347298-7kqrl3rv	977	19	epididymis	epididymis	NN
cord-347298-7kqrl3rv	977	20	as	as	RB
cord-347298-7kqrl3rv	977	21	well	well	RB
cord-347298-7kqrl3rv	977	22	,	,	,
cord-347298-7kqrl3rv	977	23	and	and	CC
cord-347298-7kqrl3rv	977	24	that	that	IN
cord-347298-7kqrl3rv	977	25	at	at	IN
cord-347298-7kqrl3rv	977	26	least	least	JJS
cord-347298-7kqrl3rv	977	27	some	some	DT
cord-347298-7kqrl3rv	977	28	of	of	IN
cord-347298-7kqrl3rv	977	29	these	these	DT
cord-347298-7kqrl3rv	977	30	effects	effect	NNS
cord-347298-7kqrl3rv	977	31	may	may	MD
cord-347298-7kqrl3rv	977	32	have	have	VB
cord-347298-7kqrl3rv	977	33	an	an	DT
cord-347298-7kqrl3rv	977	34	immunological	immunological	JJ
cord-347298-7kqrl3rv	977	35	basis	basis	NN
cord-347298-7kqrl3rv	978	1	(	(	-LRB-
cord-347298-7kqrl3rv	978	2	Aitken	Aitken	NNP
cord-347298-7kqrl3rv	978	3	et	et	NNP
cord-347298-7kqrl3rv	978	4	al	al	NNP
cord-347298-7kqrl3rv	978	5	.	.	.
cord-347298-7kqrl3rv	979	1	1999	1999	CD
cord-347298-7kqrl3rv	979	2	;	;	:
cord-347298-7kqrl3rv	979	3	Bigazzi	Bigazzi	NNP
cord-347298-7kqrl3rv	979	4	et	et	NNP
cord-347298-7kqrl3rv	979	5	al	al	NNP
cord-347298-7kqrl3rv	979	6	.	.	.
cord-347298-7kqrl3rv	980	1	1976	1976	CD
cord-347298-7kqrl3rv	981	1	;	;	:
cord-347298-7kqrl3rv	981	2	Flickinger	Flickinger	NNP
cord-347298-7kqrl3rv	981	3	et	et	NNP
cord-347298-7kqrl3rv	981	4	al	al	NNP
cord-347298-7kqrl3rv	981	5	.	.	.
cord-347298-7kqrl3rv	982	1	1990a	1990a	CD
cord-347298-7kqrl3rv	982	2	;	;	:
cord-347298-7kqrl3rv	982	3	Raleigh	Raleigh	NNP
cord-347298-7kqrl3rv	982	4	et	et	NNP
cord-347298-7kqrl3rv	982	5	al	al	NNP
cord-347298-7kqrl3rv	982	6	.	.	.
cord-347298-7kqrl3rv	982	7	2004	2004	CD
cord-347298-7kqrl3rv	982	8	)	)	-RRB-
cord-347298-7kqrl3rv	982	9	.	.	.
cord-347298-7kqrl3rv	983	1	In	in	IN
cord-347298-7kqrl3rv	983	2	certain	certain	JJ
cord-347298-7kqrl3rv	983	3	strains	strain	NNS
cord-347298-7kqrl3rv	983	4	of	of	IN
cord-347298-7kqrl3rv	983	5	rats	rat	NNS
cord-347298-7kqrl3rv	983	6	,	,	,
cord-347298-7kqrl3rv	983	7	mice	mouse	NNS
cord-347298-7kqrl3rv	983	8	,	,	,
cord-347298-7kqrl3rv	983	9	and	and	CC
cord-347298-7kqrl3rv	983	10	rabbits	rabbit	NNS
cord-347298-7kqrl3rv	983	11	,	,	,
cord-347298-7kqrl3rv	983	12	vasectomy	vasectomy	NN
cord-347298-7kqrl3rv	983	13	rapidly	rapidly	RB
cord-347298-7kqrl3rv	983	14	leads	lead	VBZ
cord-347298-7kqrl3rv	983	15	to	to	IN
cord-347298-7kqrl3rv	983	16	orchitis	orchitis	NN
cord-347298-7kqrl3rv	983	17	and	and	CC
cord-347298-7kqrl3rv	983	18	sterility	sterility	NN
cord-347298-7kqrl3rv	983	19	,	,	,
cord-347298-7kqrl3rv	983	20	so	so	CC
cord-347298-7kqrl3rv	983	21	it	-PRON-	PRP
cord-347298-7kqrl3rv	983	22	is	be	VBZ
cord-347298-7kqrl3rv	983	23	not	not	RB
cord-347298-7kqrl3rv	983	24	clear	clear	JJ
cord-347298-7kqrl3rv	983	25	why	why	WRB
cord-347298-7kqrl3rv	983	26	this	this	DT
cord-347298-7kqrl3rv	983	27	degree	degree	NN
cord-347298-7kqrl3rv	983	28	of	of	IN
cord-347298-7kqrl3rv	983	29	damage	damage	NN
cord-347298-7kqrl3rv	983	30	is	be	VBZ
cord-347298-7kqrl3rv	983	31	so	so	RB
cord-347298-7kqrl3rv	983	32	rare	rare	JJ
cord-347298-7kqrl3rv	983	33	in	in	IN
cord-347298-7kqrl3rv	983	34	humans	human	NNS
cord-347298-7kqrl3rv	983	35	.	.	.
cord-347298-7kqrl3rv	984	1	In	in	IN
cord-347298-7kqrl3rv	984	2	reality	reality	NN
cord-347298-7kqrl3rv	984	3	,	,	,
cord-347298-7kqrl3rv	984	4	the	the	DT
cord-347298-7kqrl3rv	984	5	immunology	immunology	NN
cord-347298-7kqrl3rv	984	6	of	of	IN
cord-347298-7kqrl3rv	984	7	the	the	DT
cord-347298-7kqrl3rv	984	8	male	male	JJ
cord-347298-7kqrl3rv	984	9	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	984	10	tract	tract	NN
cord-347298-7kqrl3rv	984	11	has	have	VBZ
cord-347298-7kqrl3rv	984	12	yet	yet	RB
cord-347298-7kqrl3rv	984	13	to	to	TO
cord-347298-7kqrl3rv	984	14	be	be	VB
cord-347298-7kqrl3rv	984	15	investigated	investigate	VBN
cord-347298-7kqrl3rv	984	16	in	in	IN
cord-347298-7kqrl3rv	984	17	depth	depth	NN
cord-347298-7kqrl3rv	984	18	,	,	,
cord-347298-7kqrl3rv	984	19	but	but	CC
cord-347298-7kqrl3rv	984	20	two	two	CD
cord-347298-7kqrl3rv	984	21	areas	area	NNS
cord-347298-7kqrl3rv	984	22	of	of	IN
cord-347298-7kqrl3rv	984	23	recent	recent	JJ
cord-347298-7kqrl3rv	984	24	interest	interest	NN
cord-347298-7kqrl3rv	984	25	are	be	VBP
cord-347298-7kqrl3rv	984	26	worth	worth	JJ
cord-347298-7kqrl3rv	984	27	highlighting	highlight	VBG
cord-347298-7kqrl3rv	984	28	:	:	:
cord-347298-7kqrl3rv	984	29	the	the	DT
cord-347298-7kqrl3rv	984	30	TLRs	TLRs	NNPS
cord-347298-7kqrl3rv	984	31	and	and	CC
cord-347298-7kqrl3rv	984	32	the	the	DT
cord-347298-7kqrl3rv	984	33	defensins	defensin	NNS
cord-347298-7kqrl3rv	984	34	.	.	.
cord-347298-7kqrl3rv	985	1	Given	give	VBN
cord-347298-7kqrl3rv	985	2	the	the	DT
cord-347298-7kqrl3rv	985	3	exposure	exposure	NN
cord-347298-7kqrl3rv	985	4	to	to	IN
cord-347298-7kqrl3rv	985	5	the	the	DT
cord-347298-7kqrl3rv	985	6	external	external	JJ
cord-347298-7kqrl3rv	985	7	environment	environment	NN
cord-347298-7kqrl3rv	985	8	,	,	,
cord-347298-7kqrl3rv	985	9	it	-PRON-	PRP
cord-347298-7kqrl3rv	985	10	is	be	VBZ
cord-347298-7kqrl3rv	985	11	not	not	RB
cord-347298-7kqrl3rv	985	12	surprising	surprising	JJ
cord-347298-7kqrl3rv	985	13	that	that	IN
cord-347298-7kqrl3rv	985	14	the	the	DT
cord-347298-7kqrl3rv	985	15	TLRs	tlr	NNS
cord-347298-7kqrl3rv	985	16	as	as	RB
cord-347298-7kqrl3rv	985	17	well	well	RB
cord-347298-7kqrl3rv	985	18	as	as	IN
cord-347298-7kqrl3rv	985	19	many	many	JJ
cord-347298-7kqrl3rv	985	20	essential	essential	JJ
cord-347298-7kqrl3rv	985	21	TLR	tlr	NN
cord-347298-7kqrl3rv	985	22	-	-	HYPH
cord-347298-7kqrl3rv	985	23	related	relate	VBN
cord-347298-7kqrl3rv	985	24	genes	gene	NNS
cord-347298-7kqrl3rv	985	25	,	,	,
cord-347298-7kqrl3rv	985	26	such	such	JJ
cord-347298-7kqrl3rv	985	27	as	as	IN
cord-347298-7kqrl3rv	985	28	MyD88	MyD88	NNS
cord-347298-7kqrl3rv	985	29	,	,	,
cord-347298-7kqrl3rv	985	30	are	be	VBP
cord-347298-7kqrl3rv	985	31	expressed	express	VBN
cord-347298-7kqrl3rv	985	32	throughout	throughout	IN
cord-347298-7kqrl3rv	985	33	the	the	DT
cord-347298-7kqrl3rv	985	34	male	male	JJ
cord-347298-7kqrl3rv	985	35	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	985	36	tract	tract	NN
cord-347298-7kqrl3rv	985	37	,	,	,
cord-347298-7kqrl3rv	985	38	including	include	VBG
cord-347298-7kqrl3rv	985	39	the	the	DT
cord-347298-7kqrl3rv	985	40	epididymis	epididymis	NN
cord-347298-7kqrl3rv	985	41	,	,	,
cord-347298-7kqrl3rv	985	42	vas	vas	NNP
cord-347298-7kqrl3rv	985	43	deferens	deferens	NNP
cord-347298-7kqrl3rv	985	44	,	,	,
cord-347298-7kqrl3rv	985	45	and	and	CC
cord-347298-7kqrl3rv	985	46	accessory	accessory	NN
cord-347298-7kqrl3rv	985	47	glands	gland	NNS
cord-347298-7kqrl3rv	985	48	(	(	-LRB-
cord-347298-7kqrl3rv	985	49	Nishimura	Nishimura	NNP
cord-347298-7kqrl3rv	985	50	and	and	CC
cord-347298-7kqrl3rv	985	51	Naito	Naito	NNP
cord-347298-7kqrl3rv	985	52	2005	2005	CD
cord-347298-7kqrl3rv	985	53	;	;	:
cord-347298-7kqrl3rv	985	54	Palladino	Palladino	NNP
cord-347298-7kqrl3rv	985	55	et	et	NNP
cord-347298-7kqrl3rv	985	56	al	al	NNP
cord-347298-7kqrl3rv	985	57	.	.	NNP
cord-347298-7kqrl3rv	985	58	2007	2007	CD
cord-347298-7kqrl3rv	985	59	;	;	:
cord-347298-7kqrl3rv	985	60	Quintar	Quintar	NNP
cord-347298-7kqrl3rv	985	61	et	et	NNP
cord-347298-7kqrl3rv	985	62	al	al	NNP
cord-347298-7kqrl3rv	985	63	.	.	.
cord-347298-7kqrl3rv	985	64	2006	2006	CD
cord-347298-7kqrl3rv	986	1	;	;	:
cord-347298-7kqrl3rv	986	2	Rodrigues	Rodrigues	NNP
cord-347298-7kqrl3rv	986	3	et	et	NNP
cord-347298-7kqrl3rv	986	4	al	al	NNP
cord-347298-7kqrl3rv	986	5	.	.	NNP
cord-347298-7kqrl3rv	986	6	2008	2008	CD
cord-347298-7kqrl3rv	986	7	)	)	-RRB-
cord-347298-7kqrl3rv	986	8	.	.	.
cord-347298-7kqrl3rv	987	1	Expression	expression	NN
cord-347298-7kqrl3rv	987	2	is	be	VBZ
cord-347298-7kqrl3rv	987	3	found	find	VBN
cord-347298-7kqrl3rv	987	4	on	on	IN
cord-347298-7kqrl3rv	987	5	both	both	DT
cord-347298-7kqrl3rv	987	6	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	987	7	cells	cell	NNS
cord-347298-7kqrl3rv	987	8	and	and	CC
cord-347298-7kqrl3rv	987	9	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	987	10	in	in	IN
cord-347298-7kqrl3rv	987	11	these	these	DT
cord-347298-7kqrl3rv	987	12	tissues	tissue	NNS
cord-347298-7kqrl3rv	987	13	.	.	.
cord-347298-7kqrl3rv	988	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	988	2	,	,	,
cord-347298-7kqrl3rv	988	3	weak	weak	JJ
cord-347298-7kqrl3rv	988	4	expression	expression	NN
cord-347298-7kqrl3rv	988	5	of	of	IN
cord-347298-7kqrl3rv	988	6	TLR11	TLR11	NNP
cord-347298-7kqrl3rv	988	7	,	,	,
cord-347298-7kqrl3rv	988	8	originally	originally	RB
cord-347298-7kqrl3rv	988	9	localized	localize	VBN
cord-347298-7kqrl3rv	988	10	to	to	IN
cord-347298-7kqrl3rv	988	11	the	the	DT
cord-347298-7kqrl3rv	988	12	urinary	urinary	JJ
cord-347298-7kqrl3rv	988	13	tract	tract	NN
cord-347298-7kqrl3rv	988	14	of	of	IN
cord-347298-7kqrl3rv	988	15	experimental	experimental	JJ
cord-347298-7kqrl3rv	988	16	rodents	rodent	NNS
cord-347298-7kqrl3rv	988	17	,	,	,
cord-347298-7kqrl3rv	988	18	has	have	VBZ
cord-347298-7kqrl3rv	988	19	been	be	VBN
cord-347298-7kqrl3rv	988	20	detected	detect	VBN
cord-347298-7kqrl3rv	988	21	in	in	IN
cord-347298-7kqrl3rv	988	22	the	the	DT
cord-347298-7kqrl3rv	988	23	epididymis	epididymis	NN
cord-347298-7kqrl3rv	988	24	and	and	CC
cord-347298-7kqrl3rv	988	25	vas	vas	NNP
cord-347298-7kqrl3rv	988	26	deferens	deferen	NNS
cord-347298-7kqrl3rv	988	27	of	of	IN
cord-347298-7kqrl3rv	988	28	the	the	DT
cord-347298-7kqrl3rv	988	29	rat	rat	NN
cord-347298-7kqrl3rv	988	30	(	(	-LRB-
cord-347298-7kqrl3rv	988	31	Lauw	Lauw	NNP
cord-347298-7kqrl3rv	988	32	et	et	NNP
cord-347298-7kqrl3rv	988	33	al	al	NNP
cord-347298-7kqrl3rv	988	34	.	.	NNP
cord-347298-7kqrl3rv	988	35	2005	2005	CD
cord-347298-7kqrl3rv	988	36	;	;	:
cord-347298-7kqrl3rv	988	37	Palladino	Palladino	NNP
cord-347298-7kqrl3rv	988	38	et	et	NNP
cord-347298-7kqrl3rv	988	39	al	al	NNP
cord-347298-7kqrl3rv	988	40	.	.	.
cord-347298-7kqrl3rv	988	41	2007	2007	CD
cord-347298-7kqrl3rv	989	1	;	;	:
cord-347298-7kqrl3rv	989	2	Zhang	Zhang	NNP
cord-347298-7kqrl3rv	989	3	et	et	NNP
cord-347298-7kqrl3rv	989	4	al	al	NNP
cord-347298-7kqrl3rv	989	5	.	.	.
cord-347298-7kqrl3rv	989	6	2004	2004	CD
cord-347298-7kqrl3rv	989	7	)	)	-RRB-
cord-347298-7kqrl3rv	989	8	.	.	.
cord-347298-7kqrl3rv	990	1	The	the	DT
cord-347298-7kqrl3rv	990	2	importance	importance	NN
cord-347298-7kqrl3rv	990	3	of	of	IN
cord-347298-7kqrl3rv	990	4	these	these	DT
cord-347298-7kqrl3rv	990	5	molecules	molecule	NNS
cord-347298-7kqrl3rv	990	6	in	in	IN
cord-347298-7kqrl3rv	990	7	acute	acute	JJ
cord-347298-7kqrl3rv	990	8	and	and	CC
cord-347298-7kqrl3rv	990	9	chronic	chronic	JJ
cord-347298-7kqrl3rv	990	10	inflammation	inflammation	NN
cord-347298-7kqrl3rv	990	11	,	,	,
cord-347298-7kqrl3rv	990	12	and	and	CC
cord-347298-7kqrl3rv	990	13	the	the	DT
cord-347298-7kqrl3rv	990	14	response	response	NN
cord-347298-7kqrl3rv	990	15	to	to	IN
cord-347298-7kqrl3rv	990	16	infection	infection	NN
cord-347298-7kqrl3rv	990	17	,	,	,
cord-347298-7kqrl3rv	990	18	in	in	IN
cord-347298-7kqrl3rv	990	19	the	the	DT
cord-347298-7kqrl3rv	990	20	male	male	JJ
cord-347298-7kqrl3rv	990	21	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	990	22	tract	tract	NN
cord-347298-7kqrl3rv	990	23	is	be	VBZ
cord-347298-7kqrl3rv	990	24	an	an	DT
cord-347298-7kqrl3rv	990	25	important	important	JJ
cord-347298-7kqrl3rv	990	26	area	area	NN
cord-347298-7kqrl3rv	990	27	for	for	IN
cord-347298-7kqrl3rv	990	28	future	future	JJ
cord-347298-7kqrl3rv	990	29	studies	study	NNS
cord-347298-7kqrl3rv	990	30	.	.	.
cord-347298-7kqrl3rv	991	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	991	2	,	,	,
cord-347298-7kqrl3rv	991	3	changes	change	NNS
cord-347298-7kqrl3rv	991	4	in	in	IN
cord-347298-7kqrl3rv	991	5	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	991	6	to	to	IN
cord-347298-7kqrl3rv	991	7	inflammation	inflammation	NN
cord-347298-7kqrl3rv	991	8	through	through	IN
cord-347298-7kqrl3rv	991	9	polymorphisms	polymorphism	NNS
cord-347298-7kqrl3rv	991	10	in	in	IN
cord-347298-7kqrl3rv	991	11	the	the	DT
cord-347298-7kqrl3rv	991	12	TLRs	tlr	NNS
cord-347298-7kqrl3rv	991	13	have	have	VBP
cord-347298-7kqrl3rv	991	14	been	be	VBN
cord-347298-7kqrl3rv	991	15	associated	associate	VBN
cord-347298-7kqrl3rv	991	16	with	with	IN
cord-347298-7kqrl3rv	991	17	differences	difference	NNS
cord-347298-7kqrl3rv	991	18	in	in	IN
cord-347298-7kqrl3rv	991	19	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	991	20	to	to	IN
cord-347298-7kqrl3rv	991	21	the	the	DT
cord-347298-7kqrl3rv	991	22	onset	onset	NN
cord-347298-7kqrl3rv	991	23	of	of	IN
cord-347298-7kqrl3rv	991	24	cancer	cancer	NN
cord-347298-7kqrl3rv	991	25	in	in	IN
cord-347298-7kqrl3rv	991	26	the	the	DT
cord-347298-7kqrl3rv	991	27	prostate	prostate	NN
cord-347298-7kqrl3rv	991	28	(	(	-LRB-
cord-347298-7kqrl3rv	991	29	Sun	Sun	NNP
cord-347298-7kqrl3rv	991	30	et	et	FW
cord-347298-7kqrl3rv	991	31	al	al	NNP
cord-347298-7kqrl3rv	991	32	.	.	NNP
cord-347298-7kqrl3rv	991	33	2005	2005	CD
cord-347298-7kqrl3rv	991	34	;	;	:
cord-347298-7kqrl3rv	991	35	Zheng	Zheng	NNP
cord-347298-7kqrl3rv	991	36	et	et	NNP
cord-347298-7kqrl3rv	991	37	al	al	NNP
cord-347298-7kqrl3rv	991	38	.	.	.
cord-347298-7kqrl3rv	991	39	2004	2004	CD
cord-347298-7kqrl3rv	991	40	)	)	-RRB-
cord-347298-7kqrl3rv	991	41	.	.	.
cord-347298-7kqrl3rv	992	1	Defensins	defensin	NNS
cord-347298-7kqrl3rv	992	2	are	be	VBP
cord-347298-7kqrl3rv	992	3	small	small	JJ
cord-347298-7kqrl3rv	992	4	(	(	-LRB-
cord-347298-7kqrl3rv	992	5	3	3	CD
cord-347298-7kqrl3rv	992	6	-	-	SYM
cord-347298-7kqrl3rv	992	7	4	4	CD
cord-347298-7kqrl3rv	992	8	kDa	kDa	NNPS
cord-347298-7kqrl3rv	992	9	)	)	-RRB-
cord-347298-7kqrl3rv	992	10	positively	positively	RB
cord-347298-7kqrl3rv	992	11	charged	charge	VBD
cord-347298-7kqrl3rv	992	12	peptides	peptide	NNS
cord-347298-7kqrl3rv	992	13	that	that	WDT
cord-347298-7kqrl3rv	992	14	are	be	VBP
cord-347298-7kqrl3rv	992	15	able	able	JJ
cord-347298-7kqrl3rv	992	16	to	to	TO
cord-347298-7kqrl3rv	992	17	disrupt	disrupt	VB
cord-347298-7kqrl3rv	992	18	bacteria	bacteria	NNS
cord-347298-7kqrl3rv	992	19	,	,	,
cord-347298-7kqrl3rv	992	20	fungi	fungus	NNS
cord-347298-7kqrl3rv	992	21	,	,	,
cord-347298-7kqrl3rv	992	22	parasites	parasite	NNS
cord-347298-7kqrl3rv	992	23	,	,	,
cord-347298-7kqrl3rv	992	24	and	and	CC
cord-347298-7kqrl3rv	992	25	some	some	DT
cord-347298-7kqrl3rv	992	26	enveloped	envelop	VBN
cord-347298-7kqrl3rv	992	27	viruses	virus	NNS
cord-347298-7kqrl3rv	992	28	by	by	IN
cord-347298-7kqrl3rv	992	29	forming	form	VBG
cord-347298-7kqrl3rv	992	30	multimeric	multimeric	JJ
cord-347298-7kqrl3rv	992	31	pores	pore	NNS
cord-347298-7kqrl3rv	992	32	in	in	IN
cord-347298-7kqrl3rv	992	33	the	the	DT
cord-347298-7kqrl3rv	992	34	pathogen	pathogen	NN
cord-347298-7kqrl3rv	992	35	membrane	membrane	NN
cord-347298-7kqrl3rv	992	36	(	(	-LRB-
cord-347298-7kqrl3rv	992	37	Selsted	Selsted	NNP
cord-347298-7kqrl3rv	992	38	and	and	CC
cord-347298-7kqrl3rv	992	39	Ouellette	Ouellette	NNP
cord-347298-7kqrl3rv	992	40	2005	2005	CD
cord-347298-7kqrl3rv	992	41	)	)	-RRB-
cord-347298-7kqrl3rv	992	42	.	.	.
cord-347298-7kqrl3rv	993	1	The	the	DT
cord-347298-7kqrl3rv	993	2	-defensins	-defensin	NNS
cord-347298-7kqrl3rv	993	3	are	be	VBP
cord-347298-7kqrl3rv	993	4	produced	produce	VBN
cord-347298-7kqrl3rv	993	5	by	by	IN
cord-347298-7kqrl3rv	993	6	most	most	JJS
cord-347298-7kqrl3rv	993	7	mucosal	mucosal	JJ
cord-347298-7kqrl3rv	993	8	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	993	9	tissues	tissue	NNS
cord-347298-7kqrl3rv	993	10	,	,	,
cord-347298-7kqrl3rv	993	11	including	include	VBG
cord-347298-7kqrl3rv	993	12	the	the	DT
cord-347298-7kqrl3rv	993	13	testis	testis	NN
cord-347298-7kqrl3rv	993	14	and	and	CC
cord-347298-7kqrl3rv	993	15	epididymis	epididymis	NN
cord-347298-7kqrl3rv	993	16	(	(	-LRB-
cord-347298-7kqrl3rv	993	17	Com	com	NN
cord-347298-7kqrl3rv	993	18	et	et	FW
cord-347298-7kqrl3rv	993	19	al	al	NNP
cord-347298-7kqrl3rv	993	20	.	.	NNP
cord-347298-7kqrl3rv	993	21	2003	2003	CD
cord-347298-7kqrl3rv	993	22	)	)	-RRB-
cord-347298-7kqrl3rv	993	23	,	,	,
cord-347298-7kqrl3rv	993	24	and	and	CC
cord-347298-7kqrl3rv	993	25	their	-PRON-	PRP$
cord-347298-7kqrl3rv	993	26	production	production	NN
cord-347298-7kqrl3rv	993	27	is	be	VBZ
cord-347298-7kqrl3rv	993	28	stimulated	stimulate	VBN
cord-347298-7kqrl3rv	993	29	via	via	IN
cord-347298-7kqrl3rv	993	30	TLR	TLR	NNP
cord-347298-7kqrl3rv	993	31	activation	activation	NN
cord-347298-7kqrl3rv	993	32	and	and	CC
cord-347298-7kqrl3rv	993	33	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	993	34	.	.	.
cord-347298-7kqrl3rv	994	1	A	a	DT
cord-347298-7kqrl3rv	994	2	number	number	NN
cord-347298-7kqrl3rv	994	3	of	of	IN
cord-347298-7kqrl3rv	994	4	epididymal	epididymal	JJ
cord-347298-7kqrl3rv	994	5	-	-	HYPH
cord-347298-7kqrl3rv	994	6	specificdefensins	specificdefensin	NNS
cord-347298-7kqrl3rv	994	7	have	have	VBP
cord-347298-7kqrl3rv	994	8	been	be	VBN
cord-347298-7kqrl3rv	994	9	identified	identify	VBN
cord-347298-7kqrl3rv	994	10	in	in	IN
cord-347298-7kqrl3rv	994	11	the	the	DT
cord-347298-7kqrl3rv	994	12	mouse	mouse	NN
cord-347298-7kqrl3rv	994	13	and	and	CC
cord-347298-7kqrl3rv	994	14	the	the	DT
cord-347298-7kqrl3rv	994	15	rat	rat	NN
cord-347298-7kqrl3rv	994	16	(	(	-LRB-
cord-347298-7kqrl3rv	994	17	Li	Li	NNP
cord-347298-7kqrl3rv	994	18	et	et	NNP
cord-347298-7kqrl3rv	994	19	al	al	NNP
cord-347298-7kqrl3rv	994	20	.	.	NNP
cord-347298-7kqrl3rv	994	21	2001	2001	CD
cord-347298-7kqrl3rv	994	22	;	;	:
cord-347298-7kqrl3rv	994	23	Jalkanen	Jalkanen	NNP
cord-347298-7kqrl3rv	994	24	et	et	NNP
cord-347298-7kqrl3rv	994	25	al	al	NNP
cord-347298-7kqrl3rv	994	26	.	.	NNP
cord-347298-7kqrl3rv	994	27	2005	2005	CD
cord-347298-7kqrl3rv	994	28	;	;	:
cord-347298-7kqrl3rv	994	29	Yamaguchi	Yamaguchi	NNP
cord-347298-7kqrl3rv	994	30	et	et	NNP
cord-347298-7kqrl3rv	994	31	al	al	NNP
cord-347298-7kqrl3rv	994	32	.	.	.
cord-347298-7kqrl3rv	995	1	2002	2002	CD
cord-347298-7kqrl3rv	995	2	;	;	:
cord-347298-7kqrl3rv	995	3	Yenugu	Yenugu	NNP
cord-347298-7kqrl3rv	995	4	et	et	NNP
cord-347298-7kqrl3rv	995	5	al	al	NNP
cord-347298-7kqrl3rv	995	6	.	.	.
cord-347298-7kqrl3rv	996	1	2004	2004	CD
cord-347298-7kqrl3rv	996	2	;	;	:
cord-347298-7kqrl3rv	996	3	Zhou	Zhou	NNP
cord-347298-7kqrl3rv	996	4	et	et	NNP
cord-347298-7kqrl3rv	996	5	al	al	NNP
cord-347298-7kqrl3rv	996	6	.	.	.
cord-347298-7kqrl3rv	996	7	2004	2004	CD
cord-347298-7kqrl3rv	996	8	)	)	-RRB-
cord-347298-7kqrl3rv	996	9	,	,	,
cord-347298-7kqrl3rv	996	10	and	and	CC
cord-347298-7kqrl3rv	996	11	a	a	DT
cord-347298-7kqrl3rv	996	12	role	role	NN
cord-347298-7kqrl3rv	996	13	for	for	IN
cord-347298-7kqrl3rv	996	14	androgen	androgen	NN
cord-347298-7kqrl3rv	996	15	in	in	IN
cord-347298-7kqrl3rv	996	16	their	-PRON-	PRP$
cord-347298-7kqrl3rv	996	17	regulation	regulation	NN
cord-347298-7kqrl3rv	996	18	has	have	VBZ
cord-347298-7kqrl3rv	996	19	been	be	VBN
cord-347298-7kqrl3rv	996	20	indicated	indicate	VBN
cord-347298-7kqrl3rv	996	21	(	(	-LRB-
cord-347298-7kqrl3rv	996	22	Jalkanen	Jalkanen	NNP
cord-347298-7kqrl3rv	996	23	et	et	NNP
cord-347298-7kqrl3rv	996	24	al	al	NNP
cord-347298-7kqrl3rv	996	25	.	.	.
cord-347298-7kqrl3rv	996	26	2005	2005	CD
cord-347298-7kqrl3rv	997	1	;	;	:
cord-347298-7kqrl3rv	997	2	Yenugu	Yenugu	NNP
cord-347298-7kqrl3rv	997	3	et	et	NNP
cord-347298-7kqrl3rv	997	4	al	al	NNP
cord-347298-7kqrl3rv	997	5	.	.	.
cord-347298-7kqrl3rv	997	6	2004	2004	CD
cord-347298-7kqrl3rv	997	7	)	)	-RRB-
cord-347298-7kqrl3rv	997	8	.	.	.
cord-347298-7kqrl3rv	998	1	Apart	apart	RB
cord-347298-7kqrl3rv	998	2	from	from	IN
cord-347298-7kqrl3rv	998	3	their	-PRON-	PRP$
cord-347298-7kqrl3rv	998	4	obvious	obvious	JJ
cord-347298-7kqrl3rv	998	5	role	role	NN
cord-347298-7kqrl3rv	998	6	in	in	IN
cord-347298-7kqrl3rv	998	7	protection	protection	NN
cord-347298-7kqrl3rv	998	8	against	against	IN
cord-347298-7kqrl3rv	998	9	pathogens	pathogen	NNS
cord-347298-7kqrl3rv	998	10	,	,	,
cord-347298-7kqrl3rv	998	11	defensins	defensin	NNS
cord-347298-7kqrl3rv	998	12	may	may	MD
cord-347298-7kqrl3rv	998	13	have	have	VB
cord-347298-7kqrl3rv	998	14	other	other	JJ
cord-347298-7kqrl3rv	998	15	functions	function	NNS
cord-347298-7kqrl3rv	998	16	in	in	IN
cord-347298-7kqrl3rv	998	17	the	the	DT
cord-347298-7kqrl3rv	998	18	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	998	19	tract	tract	NN
cord-347298-7kqrl3rv	998	20	.	.	.
cord-347298-7kqrl3rv	999	1	The	the	DT
cord-347298-7kqrl3rv	999	2	novel	novel	JJ
cord-347298-7kqrl3rv	999	3	-defensin	-defensin	NN
cord-347298-7kqrl3rv	999	4	,	,	,
cord-347298-7kqrl3rv	999	5	Bin1b	Bin1b	NNP
cord-347298-7kqrl3rv	999	6	,	,	,
cord-347298-7kqrl3rv	999	7	which	which	WDT
cord-347298-7kqrl3rv	999	8	is	be	VBZ
cord-347298-7kqrl3rv	999	9	exclusively	exclusively	RB
cord-347298-7kqrl3rv	999	10	produced	produce	VBN
cord-347298-7kqrl3rv	999	11	and	and	CC
cord-347298-7kqrl3rv	999	12	secreted	secrete	VBN
cord-347298-7kqrl3rv	999	13	by	by	IN
cord-347298-7kqrl3rv	999	14	the	the	DT
cord-347298-7kqrl3rv	999	15	rat	rat	NN
cord-347298-7kqrl3rv	999	16	caput	caput	NN
cord-347298-7kqrl3rv	999	17	epididymis	epididymis	NN
cord-347298-7kqrl3rv	999	18	,	,	,
cord-347298-7kqrl3rv	999	19	binds	bind	VBZ
cord-347298-7kqrl3rv	999	20	to	to	IN
cord-347298-7kqrl3rv	999	21	sperm	sperm	NN
cord-347298-7kqrl3rv	999	22	(	(	-LRB-
cord-347298-7kqrl3rv	999	23	Li	Li	NNP
cord-347298-7kqrl3rv	999	24	et	et	NNP
cord-347298-7kqrl3rv	999	25	al	al	NNP
cord-347298-7kqrl3rv	999	26	.	.	NNP
cord-347298-7kqrl3rv	999	27	2001	2001	CD
cord-347298-7kqrl3rv	999	28	;	;	:
cord-347298-7kqrl3rv	999	29	Zhou	Zhou	NNP
cord-347298-7kqrl3rv	999	30	et	et	NNP
cord-347298-7kqrl3rv	999	31	al	al	NNP
cord-347298-7kqrl3rv	999	32	.	.	.
cord-347298-7kqrl3rv	999	33	2004	2004	CD
cord-347298-7kqrl3rv	999	34	)	)	-RRB-
cord-347298-7kqrl3rv	999	35	,	,	,
cord-347298-7kqrl3rv	999	36	and	and	CC
cord-347298-7kqrl3rv	999	37	blocking	block	VBG
cord-347298-7kqrl3rv	999	38	Bin1b	Bin1b	NNP
cord-347298-7kqrl3rv	999	39	reduces	reduce	VBZ
cord-347298-7kqrl3rv	999	40	sperm	sperm	NN
cord-347298-7kqrl3rv	999	41	motility	motility	NN
cord-347298-7kqrl3rv	999	42	in	in	IN
cord-347298-7kqrl3rv	999	43	vivo	vivo	NN
cord-347298-7kqrl3rv	999	44	,	,	,
cord-347298-7kqrl3rv	999	45	suggesting	suggest	VBG
cord-347298-7kqrl3rv	999	46	a	a	DT
cord-347298-7kqrl3rv	999	47	novel	novel	JJ
cord-347298-7kqrl3rv	999	48	role	role	NN
cord-347298-7kqrl3rv	999	49	for	for	IN
cord-347298-7kqrl3rv	999	50	this	this	DT
cord-347298-7kqrl3rv	999	51	molecule	molecule	NN
cord-347298-7kqrl3rv	999	52	in	in	IN
cord-347298-7kqrl3rv	999	53	sperm	sperm	NN
cord-347298-7kqrl3rv	999	54	maturation	maturation	NN
cord-347298-7kqrl3rv	999	55	(	(	-LRB-
cord-347298-7kqrl3rv	999	56	Zhou	Zhou	NNP
cord-347298-7kqrl3rv	999	57	et	et	NNP
cord-347298-7kqrl3rv	999	58	al	al	NNP
cord-347298-7kqrl3rv	999	59	.	.	.
cord-347298-7kqrl3rv	999	60	2004	2004	CD
cord-347298-7kqrl3rv	999	61	)	)	-RRB-
cord-347298-7kqrl3rv	999	62	.	.	.
cord-347298-7kqrl3rv	1000	1	In	in	IN
cord-347298-7kqrl3rv	1000	2	humans	human	NNS
cord-347298-7kqrl3rv	1000	3	,	,	,
cord-347298-7kqrl3rv	1000	4	semen	semen	NN
cord-347298-7kqrl3rv	1000	5	is	be	VBZ
cord-347298-7kqrl3rv	1000	6	the	the	DT
cord-347298-7kqrl3rv	1000	7	most	most	RBS
cord-347298-7kqrl3rv	1000	8	accessible	accessible	JJ
cord-347298-7kqrl3rv	1000	9	window	window	NN
cord-347298-7kqrl3rv	1000	10	into	into	IN
cord-347298-7kqrl3rv	1000	11	the	the	DT
cord-347298-7kqrl3rv	1000	12	health	health	NN
cord-347298-7kqrl3rv	1000	13	of	of	IN
cord-347298-7kqrl3rv	1000	14	the	the	DT
cord-347298-7kqrl3rv	1000	15	male	male	JJ
cord-347298-7kqrl3rv	1000	16	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1000	17	system	system	NN
cord-347298-7kqrl3rv	1000	18	,	,	,
cord-347298-7kqrl3rv	1000	19	as	as	IN
cord-347298-7kqrl3rv	1000	20	it	-PRON-	PRP
cord-347298-7kqrl3rv	1000	21	is	be	VBZ
cord-347298-7kqrl3rv	1000	22	the	the	DT
cord-347298-7kqrl3rv	1000	23	number	number	NN
cord-347298-7kqrl3rv	1000	24	and	and	CC
cord-347298-7kqrl3rv	1000	25	quality	quality	NN
cord-347298-7kqrl3rv	1000	26	of	of	IN
cord-347298-7kqrl3rv	1000	27	sperm	sperm	NN
cord-347298-7kqrl3rv	1000	28	in	in	IN
cord-347298-7kqrl3rv	1000	29	the	the	DT
cord-347298-7kqrl3rv	1000	30	semen	semen	NN
cord-347298-7kqrl3rv	1000	31	that	that	WDT
cord-347298-7kqrl3rv	1000	32	provide	provide	VBP
cord-347298-7kqrl3rv	1000	33	the	the	DT
cord-347298-7kqrl3rv	1000	34	principal	principal	JJ
cord-347298-7kqrl3rv	1000	35	foci	foci	NN
cord-347298-7kqrl3rv	1000	36	for	for	IN
cord-347298-7kqrl3rv	1000	37	male	male	JJ
cord-347298-7kqrl3rv	1000	38	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1000	39	toxicity	toxicity	NN
cord-347298-7kqrl3rv	1000	40	outcomes	outcome	NNS
cord-347298-7kqrl3rv	1000	41	.	.	.
cord-347298-7kqrl3rv	1001	1	However	however	RB
cord-347298-7kqrl3rv	1001	2	,	,	,
cord-347298-7kqrl3rv	1001	3	semen	semen	NN
cord-347298-7kqrl3rv	1001	4	is	be	VBZ
cord-347298-7kqrl3rv	1001	5	a	a	DT
cord-347298-7kqrl3rv	1001	6	complex	complex	JJ
cord-347298-7kqrl3rv	1001	7	secretion	secretion	NN
cord-347298-7kqrl3rv	1001	8	,	,	,
cord-347298-7kqrl3rv	1001	9	comprising	comprise	VBG
cord-347298-7kqrl3rv	1001	10	many	many	JJ
cord-347298-7kqrl3rv	1001	11	components	component	NNS
cord-347298-7kqrl3rv	1001	12	,	,	,
cord-347298-7kqrl3rv	1001	13	including	include	VBG
cord-347298-7kqrl3rv	1001	14	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1001	15	,	,	,
cord-347298-7kqrl3rv	1001	16	immunoglobulins	immunoglobulin	NNS
cord-347298-7kqrl3rv	1001	17	,	,	,
cord-347298-7kqrl3rv	1001	18	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1001	19	,	,	,
cord-347298-7kqrl3rv	1001	20	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	1001	21	,	,	,
cord-347298-7kqrl3rv	1001	22	and	and	CC
cord-347298-7kqrl3rv	1001	23	various	various	JJ
cord-347298-7kqrl3rv	1001	24	immunosuppressives	immunosuppressive	NNS
cord-347298-7kqrl3rv	1001	25	.	.	.
cord-347298-7kqrl3rv	1002	1	Changes	change	NNS
cord-347298-7kqrl3rv	1002	2	in	in	IN
cord-347298-7kqrl3rv	1002	3	the	the	DT
cord-347298-7kqrl3rv	1002	4	number	number	NN
cord-347298-7kqrl3rv	1002	5	or	or	CC
cord-347298-7kqrl3rv	1002	6	activity	activity	NN
cord-347298-7kqrl3rv	1002	7	of	of	IN
cord-347298-7kqrl3rv	1002	8	these	these	DT
cord-347298-7kqrl3rv	1002	9	immunological	immunological	JJ
cord-347298-7kqrl3rv	1002	10	components	component	NNS
cord-347298-7kqrl3rv	1002	11	of	of	IN
cord-347298-7kqrl3rv	1002	12	the	the	DT
cord-347298-7kqrl3rv	1002	13	semen	semen	NN
cord-347298-7kqrl3rv	1002	14	are	be	VBP
cord-347298-7kqrl3rv	1002	15	also	also	RB
cord-347298-7kqrl3rv	1002	16	potential	potential	JJ
cord-347298-7kqrl3rv	1002	17	indicators	indicator	NNS
cord-347298-7kqrl3rv	1002	18	of	of	IN
cord-347298-7kqrl3rv	1002	19	toxic	toxic	JJ
cord-347298-7kqrl3rv	1002	20	actions	action	NNS
cord-347298-7kqrl3rv	1002	21	within	within	IN
cord-347298-7kqrl3rv	1002	22	the	the	DT
cord-347298-7kqrl3rv	1002	23	tract	tract	NN
cord-347298-7kqrl3rv	1002	24	.	.	.
cord-347298-7kqrl3rv	1003	1	Elevated	elevated	JJ
cord-347298-7kqrl3rv	1003	2	numbers	number	NNS
cord-347298-7kqrl3rv	1003	3	of	of	IN
cord-347298-7kqrl3rv	1003	4	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1003	5	in	in	IN
cord-347298-7kqrl3rv	1003	6	the	the	DT
cord-347298-7kqrl3rv	1003	7	semen	semen	NN
cord-347298-7kqrl3rv	1003	8	are	be	VBP
cord-347298-7kqrl3rv	1003	9	generally	generally	RB
cord-347298-7kqrl3rv	1003	10	considered	consider	VBN
cord-347298-7kqrl3rv	1003	11	to	to	TO
cord-347298-7kqrl3rv	1003	12	be	be	VB
cord-347298-7kqrl3rv	1003	13	an	an	DT
cord-347298-7kqrl3rv	1003	14	indication	indication	NN
cord-347298-7kqrl3rv	1003	15	of	of	IN
cord-347298-7kqrl3rv	1003	16	infection	infection	NN
cord-347298-7kqrl3rv	1003	17	,	,	,
cord-347298-7kqrl3rv	1003	18	but	but	CC
cord-347298-7kqrl3rv	1003	19	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1003	20	are	be	VBP
cord-347298-7kqrl3rv	1003	21	present	present	JJ
cord-347298-7kqrl3rv	1003	22	even	even	RB
cord-347298-7kqrl3rv	1003	23	in	in	IN
cord-347298-7kqrl3rv	1003	24	the	the	DT
cord-347298-7kqrl3rv	1003	25	semen	semen	NN
cord-347298-7kqrl3rv	1003	26	of	of	IN
cord-347298-7kqrl3rv	1003	27	men	man	NNS
cord-347298-7kqrl3rv	1003	28	with	with	IN
cord-347298-7kqrl3rv	1003	29	normal	normal	JJ
cord-347298-7kqrl3rv	1003	30	fertility	fertility	NN
cord-347298-7kqrl3rv	1003	31	Barratt	Barratt	NNP
cord-347298-7kqrl3rv	1003	32	et	et	NNP
cord-347298-7kqrl3rv	1003	33	al	al	NNP
cord-347298-7kqrl3rv	1003	34	.	.	NNP
cord-347298-7kqrl3rv	1003	35	1991	1991	CD
cord-347298-7kqrl3rv	1003	36	)	)	-RRB-
cord-347298-7kqrl3rv	1003	37	.	.	.
cord-347298-7kqrl3rv	1004	1	The	the	DT
cord-347298-7kqrl3rv	1004	2	origin	origin	NN
cord-347298-7kqrl3rv	1004	3	of	of	IN
cord-347298-7kqrl3rv	1004	4	these	these	DT
cord-347298-7kqrl3rv	1004	5	cells	cell	NNS
cord-347298-7kqrl3rv	1004	6	is	be	VBZ
cord-347298-7kqrl3rv	1004	7	somewhat	somewhat	RB
cord-347298-7kqrl3rv	1004	8	obscure	obscure	JJ
cord-347298-7kqrl3rv	1004	9	.	.	.
cord-347298-7kqrl3rv	1005	1	Evidence	evidence	NN
cord-347298-7kqrl3rv	1005	2	suggests	suggest	VBZ
cord-347298-7kqrl3rv	1005	3	that	that	IN
cord-347298-7kqrl3rv	1005	4	the	the	DT
cord-347298-7kqrl3rv	1005	5	epididymis	epididymis	NN
cord-347298-7kqrl3rv	1005	6	or	or	CC
cord-347298-7kqrl3rv	1005	7	vas	vas	NNP
cord-347298-7kqrl3rv	1005	8	may	may	MD
cord-347298-7kqrl3rv	1005	9	be	be	VB
cord-347298-7kqrl3rv	1005	10	a	a	DT
cord-347298-7kqrl3rv	1005	11	major	major	JJ
cord-347298-7kqrl3rv	1005	12	source	source	NN
cord-347298-7kqrl3rv	1005	13	(	(	-LRB-
cord-347298-7kqrl3rv	1005	14	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	1005	15	et	et	NNP
cord-347298-7kqrl3rv	1005	16	al	al	NNP
cord-347298-7kqrl3rv	1005	17	.	.	.
cord-347298-7kqrl3rv	1005	18	1991	1991	CD
cord-347298-7kqrl3rv	1005	19	;	;	:
cord-347298-7kqrl3rv	1005	20	Schwartz	Schwartz	NNP
cord-347298-7kqrl3rv	1005	21	1990	1990	CD
cord-347298-7kqrl3rv	1005	22	)	)	-RRB-
cord-347298-7kqrl3rv	1005	23	,	,	,
cord-347298-7kqrl3rv	1005	24	but	but	CC
cord-347298-7kqrl3rv	1005	25	the	the	DT
cord-347298-7kqrl3rv	1005	26	main	main	JJ
cord-347298-7kqrl3rv	1005	27	leukocyte	leukocyte	NN
cord-347298-7kqrl3rv	1005	28	subset	subset	VBN
cord-347298-7kqrl3rv	1005	29	present	present	NN
cord-347298-7kqrl3rv	1005	30	in	in	IN
cord-347298-7kqrl3rv	1005	31	most	most	JJS
cord-347298-7kqrl3rv	1005	32	semen	semen	NN
cord-347298-7kqrl3rv	1005	33	samples	sample	NNS
cord-347298-7kqrl3rv	1005	34	are	be	VBP
cord-347298-7kqrl3rv	1005	35	neutrophils	neutrophil	NNS
cord-347298-7kqrl3rv	1005	36	,	,	,
cord-347298-7kqrl3rv	1005	37	which	which	WDT
cord-347298-7kqrl3rv	1005	38	are	be	VBP
cord-347298-7kqrl3rv	1005	39	not	not	RB
cord-347298-7kqrl3rv	1005	40	a	a	DT
cord-347298-7kqrl3rv	1005	41	normal	normal	JJ
cord-347298-7kqrl3rv	1005	42	feature	feature	NN
cord-347298-7kqrl3rv	1005	43	of	of	IN
cord-347298-7kqrl3rv	1005	44	the	the	DT
cord-347298-7kqrl3rv	1005	45	tissues	tissue	NNS
cord-347298-7kqrl3rv	1005	46	of	of	IN
cord-347298-7kqrl3rv	1005	47	the	the	DT
cord-347298-7kqrl3rv	1005	48	genital	genital	JJ
cord-347298-7kqrl3rv	1005	49	tract	tract	NN
cord-347298-7kqrl3rv	1005	50	el	el	NNP
cord-347298-7kqrl3rv	1005	51	-	-	HYPH
cord-347298-7kqrl3rv	1005	52	Demiry	Demiry	NNP
cord-347298-7kqrl3rv	1005	53	et	et	FW
cord-347298-7kqrl3rv	1005	54	al	al	NNP
cord-347298-7kqrl3rv	1005	55	.	.	.
cord-347298-7kqrl3rv	1006	1	1986	1986	CD
cord-347298-7kqrl3rv	1006	2	;	;	:
cord-347298-7kqrl3rv	1006	3	Wolff	Wolff	NNP
cord-347298-7kqrl3rv	1006	4	and	and	CC
cord-347298-7kqrl3rv	1006	5	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	1006	6	1988	1988	CD
cord-347298-7kqrl3rv	1006	7	)	)	-RRB-
cord-347298-7kqrl3rv	1006	8	.	.	.
cord-347298-7kqrl3rv	1007	1	The	the	DT
cord-347298-7kqrl3rv	1007	2	impact	impact	NN
cord-347298-7kqrl3rv	1007	3	of	of	IN
cord-347298-7kqrl3rv	1007	4	these	these	DT
cord-347298-7kqrl3rv	1007	5	cells	cell	NNS
cord-347298-7kqrl3rv	1007	6	on	on	IN
cord-347298-7kqrl3rv	1007	7	fertility	fertility	NN
cord-347298-7kqrl3rv	1007	8	is	be	VBZ
cord-347298-7kqrl3rv	1007	9	also	also	RB
cord-347298-7kqrl3rv	1007	10	poorly	poorly	RB
cord-347298-7kqrl3rv	1007	11	understood	understand	VBN
cord-347298-7kqrl3rv	1007	12	.	.	.
cord-347298-7kqrl3rv	1008	1	Some	some	DT
cord-347298-7kqrl3rv	1008	2	studies	study	NNS
cord-347298-7kqrl3rv	1008	3	have	have	VBP
cord-347298-7kqrl3rv	1008	4	shown	show	VBN
cord-347298-7kqrl3rv	1008	5	a	a	DT
cord-347298-7kqrl3rv	1008	6	relationship	relationship	NN
cord-347298-7kqrl3rv	1008	7	between	between	IN
cord-347298-7kqrl3rv	1008	8	leukocytospermia	leukocytospermia	NN
cord-347298-7kqrl3rv	1008	9	and	and	CC
cord-347298-7kqrl3rv	1008	10	impaired	impaired	JJ
cord-347298-7kqrl3rv	1008	11	sperm	sperm	NN
cord-347298-7kqrl3rv	1008	12	function	function	NN
cord-347298-7kqrl3rv	1008	13	(	(	-LRB-
cord-347298-7kqrl3rv	1008	14	Auroux	Auroux	NNP
cord-347298-7kqrl3rv	1008	15	1984	1984	CD
cord-347298-7kqrl3rv	1008	16	;	;	:
cord-347298-7kqrl3rv	1008	17	Aziz	Aziz	NNP
cord-347298-7kqrl3rv	1008	18	et	et	NNP
cord-347298-7kqrl3rv	1008	19	al	al	NNP
cord-347298-7kqrl3rv	1008	20	.	.	.
cord-347298-7kqrl3rv	1008	21	2004	2004	CD
cord-347298-7kqrl3rv	1008	22	;	;	:
cord-347298-7kqrl3rv	1008	23	Berger	Berger	NNP
cord-347298-7kqrl3rv	1008	24	et	et	NNP
cord-347298-7kqrl3rv	1008	25	al	al	NNP
cord-347298-7kqrl3rv	1008	26	.	.	NNP
cord-347298-7kqrl3rv	1008	27	1982	1982	CD
cord-347298-7kqrl3rv	1008	28	;	;	.
cord-347298-7kqrl3rv	1009	1	Wolff	Wolff	NNP
cord-347298-7kqrl3rv	1009	2	et	et	NNP
cord-347298-7kqrl3rv	1009	3	al	al	NNP
cord-347298-7kqrl3rv	1009	4	.	.	NNP
cord-347298-7kqrl3rv	1009	5	1990	1990	CD
cord-347298-7kqrl3rv	1009	6	)	)	-RRB-
cord-347298-7kqrl3rv	1009	7	,	,	,
cord-347298-7kqrl3rv	1009	8	and	and	CC
cord-347298-7kqrl3rv	1009	9	some	some	DT
cord-347298-7kqrl3rv	1009	10	data	datum	NNS
cord-347298-7kqrl3rv	1009	11	suggest	suggest	VBP
cord-347298-7kqrl3rv	1009	12	that	that	IN
cord-347298-7kqrl3rv	1009	13	these	these	DT
cord-347298-7kqrl3rv	1009	14	cells	cell	NNS
cord-347298-7kqrl3rv	1009	15	might	may	MD
cord-347298-7kqrl3rv	1009	16	be	be	VB
cord-347298-7kqrl3rv	1009	17	a	a	DT
cord-347298-7kqrl3rv	1009	18	cause	cause	NN
cord-347298-7kqrl3rv	1009	19	of	of	IN
cord-347298-7kqrl3rv	1009	20	sperm	sperm	NN
cord-347298-7kqrl3rv	1009	21	damage	damage	NN
cord-347298-7kqrl3rv	1009	22	due	due	IN
cord-347298-7kqrl3rv	1009	23	to	to	IN
cord-347298-7kqrl3rv	1009	24	production	production	NN
cord-347298-7kqrl3rv	1009	25	of	of	IN
cord-347298-7kqrl3rv	1009	26	ROS	ROS	NNP
cord-347298-7kqrl3rv	1009	27	and	and	CC
cord-347298-7kqrl3rv	1009	28	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1009	29	(	(	-LRB-
cord-347298-7kqrl3rv	1009	30	Hill	Hill	NNP
cord-347298-7kqrl3rv	1009	31	et	et	NNP
cord-347298-7kqrl3rv	1009	32	al	al	NNP
cord-347298-7kqrl3rv	1009	33	.	.	NNP
cord-347298-7kqrl3rv	1009	34	1987	1987	CD
cord-347298-7kqrl3rv	1009	35	;	;	.
cord-347298-7kqrl3rv	1010	1	Tomlinson	Tomlinson	NNP
cord-347298-7kqrl3rv	1010	2	et	et	NNP
cord-347298-7kqrl3rv	1010	3	al	al	NNP
cord-347298-7kqrl3rv	1010	4	.	.	.
cord-347298-7kqrl3rv	1010	5	1992a	1992a	CD
cord-347298-7kqrl3rv	1010	6	)	)	-RRB-
cord-347298-7kqrl3rv	1010	7	.	.	.
cord-347298-7kqrl3rv	1011	1	Moreover	moreover	RB
cord-347298-7kqrl3rv	1011	2	,	,	,
cord-347298-7kqrl3rv	1011	3	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1011	4	may	may	MD
cord-347298-7kqrl3rv	1011	5	attack	attack	VB
cord-347298-7kqrl3rv	1011	6	the	the	DT
cord-347298-7kqrl3rv	1011	7	sperm	sperm	NN
cord-347298-7kqrl3rv	1011	8	directly	directly	RB
cord-347298-7kqrl3rv	1011	9	,	,	,
cord-347298-7kqrl3rv	1011	10	particularly	particularly	RB
cord-347298-7kqrl3rv	1011	11	in	in	IN
cord-347298-7kqrl3rv	1011	12	the	the	DT
cord-347298-7kqrl3rv	1011	13	presence	presence	NN
cord-347298-7kqrl3rv	1011	14	of	of	IN
cord-347298-7kqrl3rv	1011	15	sperm	sperm	NN
cord-347298-7kqrl3rv	1011	16	autoantibodies	autoantibody	NNS
cord-347298-7kqrl3rv	1011	17	,	,	,
cord-347298-7kqrl3rv	1011	18	and	and	CC
cord-347298-7kqrl3rv	1011	19	may	may	MD
cord-347298-7kqrl3rv	1011	20	provoke	provoke	VB
cord-347298-7kqrl3rv	1011	21	or	or	CC
cord-347298-7kqrl3rv	1011	22	mediate	mediate	VB
cord-347298-7kqrl3rv	1011	23	hostile	hostile	JJ
cord-347298-7kqrl3rv	1011	24	responses	response	NNS
cord-347298-7kqrl3rv	1011	25	in	in	IN
cord-347298-7kqrl3rv	1011	26	the	the	DT
cord-347298-7kqrl3rv	1011	27	female	female	JJ
cord-347298-7kqrl3rv	1011	28	tract	tract	NN
cord-347298-7kqrl3rv	1011	29	.	.	.
cord-347298-7kqrl3rv	1012	1	Other	other	JJ
cord-347298-7kqrl3rv	1012	2	studies	study	NNS
cord-347298-7kqrl3rv	1012	3	,	,	,
cord-347298-7kqrl3rv	1012	4	however	however	RB
cord-347298-7kqrl3rv	1012	5	,	,	,
cord-347298-7kqrl3rv	1012	6	have	have	VBP
cord-347298-7kqrl3rv	1012	7	failed	fail	VBN
cord-347298-7kqrl3rv	1012	8	to	to	TO
cord-347298-7kqrl3rv	1012	9	confirm	confirm	VB
cord-347298-7kqrl3rv	1012	10	a	a	DT
cord-347298-7kqrl3rv	1012	11	clear	clear	JJ
cord-347298-7kqrl3rv	1012	12	link	link	NN
cord-347298-7kqrl3rv	1012	13	between	between	IN
cord-347298-7kqrl3rv	1012	14	seminal	seminal	JJ
cord-347298-7kqrl3rv	1012	15	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1012	16	and	and	CC
cord-347298-7kqrl3rv	1012	17	infertility	infertility	NN
cord-347298-7kqrl3rv	1012	18	or	or	CC
cord-347298-7kqrl3rv	1012	19	sperm	sperm	NN
cord-347298-7kqrl3rv	1012	20	antibody	antibody	NN
cord-347298-7kqrl3rv	1012	21	formation	formation	NN
cord-347298-7kqrl3rv	1012	22	Barratt	Barratt	NNP
cord-347298-7kqrl3rv	1012	23	et	et	NNP
cord-347298-7kqrl3rv	1012	24	al	al	NNP
cord-347298-7kqrl3rv	1012	25	.	.	NNP
cord-347298-7kqrl3rv	1012	26	1990	1990	CD
cord-347298-7kqrl3rv	1012	27	;	;	:
cord-347298-7kqrl3rv	1012	28	Tomlinson	Tomlinson	NNP
cord-347298-7kqrl3rv	1012	29	et	et	NNP
cord-347298-7kqrl3rv	1012	30	al	al	NNP
cord-347298-7kqrl3rv	1012	31	.	.	.
cord-347298-7kqrl3rv	1012	32	1993	1993	CD
cord-347298-7kqrl3rv	1012	33	)	)	-RRB-
cord-347298-7kqrl3rv	1012	34	,	,	,
cord-347298-7kqrl3rv	1012	35	and	and	CC
cord-347298-7kqrl3rv	1012	36	it	-PRON-	PRP
cord-347298-7kqrl3rv	1012	37	has	have	VBZ
cord-347298-7kqrl3rv	1012	38	even	even	RB
cord-347298-7kqrl3rv	1012	39	been	be	VBN
cord-347298-7kqrl3rv	1012	40	suggested	suggest	VBN
cord-347298-7kqrl3rv	1012	41	that	that	IN
cord-347298-7kqrl3rv	1012	42	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1012	43	might	may	MD
cord-347298-7kqrl3rv	1012	44	play	play	VB
cord-347298-7kqrl3rv	1012	45	a	a	DT
cord-347298-7kqrl3rv	1012	46	beneficial	beneficial	JJ
cord-347298-7kqrl3rv	1012	47	role	role	NN
cord-347298-7kqrl3rv	1012	48	by	by	IN
cord-347298-7kqrl3rv	1012	49	removing	remove	VBG
cord-347298-7kqrl3rv	1012	50	abnormal	abnormal	JJ
cord-347298-7kqrl3rv	1012	51	sperm	sperm	NN
cord-347298-7kqrl3rv	1012	52	or	or	CC
cord-347298-7kqrl3rv	1012	53	by	by	IN
cord-347298-7kqrl3rv	1012	54	assisting	assist	VBG
cord-347298-7kqrl3rv	1012	55	in	in	IN
cord-347298-7kqrl3rv	1012	56	sperm	sperm	NN
cord-347298-7kqrl3rv	1012	57	capacitation	capacitation	NN
cord-347298-7kqrl3rv	1012	58	(	(	-LRB-
cord-347298-7kqrl3rv	1012	59	Tomlinson	Tomlinson	NNP
cord-347298-7kqrl3rv	1012	60	et	et	NNP
cord-347298-7kqrl3rv	1012	61	al	al	NNP
cord-347298-7kqrl3rv	1012	62	.	.	.
cord-347298-7kqrl3rv	1013	1	1992b	1992b	CD
cord-347298-7kqrl3rv	1014	1	(	(	-LRB-
cord-347298-7kqrl3rv	1014	2	Tomlinson	Tomlinson	NNP
cord-347298-7kqrl3rv	1014	3	et	et	NNP
cord-347298-7kqrl3rv	1014	4	al	al	NNP
cord-347298-7kqrl3rv	1014	5	.	.	NNP
cord-347298-7kqrl3rv	1014	6	,	,	,
cord-347298-7kqrl3rv	1014	7	1993	1993	CD
cord-347298-7kqrl3rv	1014	8	.	.	.
cord-347298-7kqrl3rv	1015	1	Molecules	molecule	NNS
cord-347298-7kqrl3rv	1015	2	with	with	IN
cord-347298-7kqrl3rv	1015	3	immunomodulatory	immunomodulatory	JJ
cord-347298-7kqrl3rv	1015	4	properties	property	NNS
cord-347298-7kqrl3rv	1015	5	in	in	IN
cord-347298-7kqrl3rv	1015	6	seminal	seminal	JJ
cord-347298-7kqrl3rv	1015	7	plasma	plasma	NN
cord-347298-7kqrl3rv	1015	8	include	include	VBP
cord-347298-7kqrl3rv	1015	9	immunoglobulins	immunoglobulin	NNS
cord-347298-7kqrl3rv	1015	10	,	,	,
cord-347298-7kqrl3rv	1015	11	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1015	12	,	,	,
cord-347298-7kqrl3rv	1015	13	and	and	CC
cord-347298-7kqrl3rv	1015	14	immunosuppressives	immunosuppressive	NNS
cord-347298-7kqrl3rv	1015	15	.	.	.
cord-347298-7kqrl3rv	1016	1	Both	both	DT
cord-347298-7kqrl3rv	1016	2	IgG	IgG	NNP
cord-347298-7kqrl3rv	1016	3	and	and	CC
cord-347298-7kqrl3rv	1016	4	IgA	IgA	NNP
cord-347298-7kqrl3rv	1016	5	are	be	VBP
cord-347298-7kqrl3rv	1016	6	the	the	DT
cord-347298-7kqrl3rv	1016	7	major	major	JJ
cord-347298-7kqrl3rv	1016	8	constituents	constituent	NNS
cord-347298-7kqrl3rv	1016	9	of	of	IN
cord-347298-7kqrl3rv	1016	10	seminal	seminal	JJ
cord-347298-7kqrl3rv	1016	11	plasma	plasma	NN
cord-347298-7kqrl3rv	1016	12	,	,	,
cord-347298-7kqrl3rv	1016	13	and	and	CC
cord-347298-7kqrl3rv	1016	14	there	there	EX
cord-347298-7kqrl3rv	1016	15	appears	appear	VBZ
cord-347298-7kqrl3rv	1016	16	to	to	TO
cord-347298-7kqrl3rv	1016	17	be	be	VB
cord-347298-7kqrl3rv	1016	18	a	a	DT
cord-347298-7kqrl3rv	1016	19	negative	negative	JJ
cord-347298-7kqrl3rv	1016	20	correlation	correlation	NN
cord-347298-7kqrl3rv	1016	21	between	between	IN
cord-347298-7kqrl3rv	1016	22	IgA	IgA	NNP
cord-347298-7kqrl3rv	1016	23	concentrations	concentration	NNS
cord-347298-7kqrl3rv	1016	24	and	and	CC
cord-347298-7kqrl3rv	1016	25	lymphosuppressive	lymphosuppressive	JJ
cord-347298-7kqrl3rv	1016	26	activity	activity	NN
cord-347298-7kqrl3rv	1016	27	in	in	IN
cord-347298-7kqrl3rv	1016	28	seminal	seminal	JJ
cord-347298-7kqrl3rv	1016	29	plasma	plasma	NN
cord-347298-7kqrl3rv	1017	1	(	(	-LRB-
cord-347298-7kqrl3rv	1017	2	Eggert	Eggert	NNP
cord-347298-7kqrl3rv	1017	3	-	-	HYPH
cord-347298-7kqrl3rv	1017	4	Kruse	Kruse	NNP
cord-347298-7kqrl3rv	1017	5	et	et	NNP
cord-347298-7kqrl3rv	1017	6	al	al	NNP
cord-347298-7kqrl3rv	1017	7	.	.	.
cord-347298-7kqrl3rv	1018	1	1996	1996	CD
cord-347298-7kqrl3rv	1018	2	;	;	:
cord-347298-7kqrl3rv	1018	3	Imade	Imade	NNP
cord-347298-7kqrl3rv	1018	4	et	et	NNP
cord-347298-7kqrl3rv	1018	5	al	al	NNP
cord-347298-7kqrl3rv	1018	6	.	.	.
cord-347298-7kqrl3rv	1019	1	1997	1997	CD
cord-347298-7kqrl3rv	1019	2	;	;	:
cord-347298-7kqrl3rv	1019	3	Moldoveanu	Moldoveanu	NNP
cord-347298-7kqrl3rv	1019	4	et	et	NNP
cord-347298-7kqrl3rv	1019	5	al	al	NNP
cord-347298-7kqrl3rv	1019	6	.	.	NNP
cord-347298-7kqrl3rv	1019	7	2005	2005	CD
cord-347298-7kqrl3rv	1019	8	)	)	-RRB-
cord-347298-7kqrl3rv	1019	9	.	.	.
cord-347298-7kqrl3rv	1020	1	These	these	DT
cord-347298-7kqrl3rv	1020	2	antibodies	antibody	NNS
cord-347298-7kqrl3rv	1020	3	may	may	MD
cord-347298-7kqrl3rv	1020	4	play	play	VB
cord-347298-7kqrl3rv	1020	5	either	either	CC
cord-347298-7kqrl3rv	1020	6	protective	protective	JJ
cord-347298-7kqrl3rv	1020	7	roles	role	NNS
cord-347298-7kqrl3rv	1020	8	in	in	IN
cord-347298-7kqrl3rv	1020	9	the	the	DT
cord-347298-7kqrl3rv	1020	10	control	control	NN
cord-347298-7kqrl3rv	1020	11	of	of	IN
cord-347298-7kqrl3rv	1020	12	immunity	immunity	NN
cord-347298-7kqrl3rv	1020	13	and	and	CC
cord-347298-7kqrl3rv	1020	14	infection	infection	NN
cord-347298-7kqrl3rv	1020	15	,	,	,
cord-347298-7kqrl3rv	1020	16	or	or	CC
cord-347298-7kqrl3rv	1020	17	destructive	destructive	JJ
cord-347298-7kqrl3rv	1020	18	roles	role	NNS
cord-347298-7kqrl3rv	1020	19	,	,	,
cord-347298-7kqrl3rv	1020	20	when	when	WRB
cord-347298-7kqrl3rv	1020	21	directed	direct	VBN
cord-347298-7kqrl3rv	1020	22	against	against	IN
cord-347298-7kqrl3rv	1020	23	functional	functional	JJ
cord-347298-7kqrl3rv	1020	24	elements	element	NNS
cord-347298-7kqrl3rv	1020	25	of	of	IN
cord-347298-7kqrl3rv	1020	26	the	the	DT
cord-347298-7kqrl3rv	1020	27	sperm	sperm	NN
cord-347298-7kqrl3rv	1020	28	.	.	.
cord-347298-7kqrl3rv	1021	1	Proinflammatory	proinflammatory	NN
cord-347298-7kqrl3rv	1021	2	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1021	3	such	such	JJ
cord-347298-7kqrl3rv	1021	4	as	as	IN
cord-347298-7kqrl3rv	1021	5	IL1	IL1	NNP
cord-347298-7kqrl3rv	1021	6	,	,	,
cord-347298-7kqrl3rv	1021	7	IL2	IL2	NNP
cord-347298-7kqrl3rv	1021	8	,	,	,
cord-347298-7kqrl3rv	1021	9	IL6	IL6	NNP
cord-347298-7kqrl3rv	1021	10	,	,	,
cord-347298-7kqrl3rv	1021	11	IL8	IL8	NNP
cord-347298-7kqrl3rv	1021	12	,	,	,
cord-347298-7kqrl3rv	1021	13	IL12	IL12	NNP
cord-347298-7kqrl3rv	1021	14	,	,	,
cord-347298-7kqrl3rv	1021	15	IL17	IL17	NNP
cord-347298-7kqrl3rv	1021	16	,	,	,
cord-347298-7kqrl3rv	1021	17	TNF	TNF	NNP
cord-347298-7kqrl3rv	1021	18	,	,	,
cord-347298-7kqrl3rv	1021	19	and	and	CC
cord-347298-7kqrl3rv	1021	20	IFN	IFN	NNP
cord-347298-7kqrl3rv	1021	21	are	be	VBP
cord-347298-7kqrl3rv	1021	22	found	find	VBN
cord-347298-7kqrl3rv	1021	23	in	in	IN
cord-347298-7kqrl3rv	1021	24	all	all	DT
cord-347298-7kqrl3rv	1021	25	seminal	seminal	JJ
cord-347298-7kqrl3rv	1021	26	plasma	plasma	NN
cord-347298-7kqrl3rv	1021	27	samples	sample	NNS
cord-347298-7kqrl3rv	1021	28	,	,	,
cord-347298-7kqrl3rv	1021	29	even	even	RB
cord-347298-7kqrl3rv	1021	30	those	those	DT
cord-347298-7kqrl3rv	1021	31	from	from	IN
cord-347298-7kqrl3rv	1021	32	men	man	NNS
cord-347298-7kqrl3rv	1021	33	with	with	IN
cord-347298-7kqrl3rv	1021	34	apparently	apparently	RB
cord-347298-7kqrl3rv	1021	35	normal	normal	JJ
cord-347298-7kqrl3rv	1021	36	fertility	fertility	NN
cord-347298-7kqrl3rv	1022	1	(	(	-LRB-
cord-347298-7kqrl3rv	1022	2	Eggert	Eggert	NNP
cord-347298-7kqrl3rv	1022	3	-	-	HYPH
cord-347298-7kqrl3rv	1022	4	Kruse	Kruse	NNP
cord-347298-7kqrl3rv	1022	5	et	et	NNP
cord-347298-7kqrl3rv	1022	6	al	al	NNP
cord-347298-7kqrl3rv	1022	7	.	.	.
cord-347298-7kqrl3rv	1023	1	2001	2001	CD
cord-347298-7kqrl3rv	1023	2	;	;	:
cord-347298-7kqrl3rv	1023	3	Huleihel	Huleihel	NNP
cord-347298-7kqrl3rv	1023	4	et	et	NNP
cord-347298-7kqrl3rv	1023	5	al	al	NNP
cord-347298-7kqrl3rv	1023	6	.	.	.
cord-347298-7kqrl3rv	1024	1	1999	1999	CD
cord-347298-7kqrl3rv	1024	2	;	;	:
cord-347298-7kqrl3rv	1024	3	Koumantakis	Koumantakis	NNP
cord-347298-7kqrl3rv	1024	4	et	et	NNP
cord-347298-7kqrl3rv	1024	5	al	al	NNP
cord-347298-7kqrl3rv	1024	6	.	.	.
cord-347298-7kqrl3rv	1025	1	1998	1998	CD
cord-347298-7kqrl3rv	1025	2	;	;	:
cord-347298-7kqrl3rv	1025	3	Maegawa	Maegawa	NNP
cord-347298-7kqrl3rv	1025	4	et	et	NNP
cord-347298-7kqrl3rv	1025	5	al	al	NNP
cord-347298-7kqrl3rv	1025	6	.	.	.
cord-347298-7kqrl3rv	1026	1	2002	2002	CD
cord-347298-7kqrl3rv	1026	2	;	;	:
cord-347298-7kqrl3rv	1026	3	Naz	Naz	NNP
cord-347298-7kqrl3rv	1026	4	and	and	CC
cord-347298-7kqrl3rv	1026	5	Evans	Evans	NNP
cord-347298-7kqrl3rv	1026	6	1998	1998	CD
cord-347298-7kqrl3rv	1026	7	;	;	:
cord-347298-7kqrl3rv	1026	8	Politch	Politch	NNP
cord-347298-7kqrl3rv	1026	9	et	et	NNP
cord-347298-7kqrl3rv	1026	10	al	al	NNP
cord-347298-7kqrl3rv	1026	11	.	.	NNP
cord-347298-7kqrl3rv	1026	12	2007	2007	CD
cord-347298-7kqrl3rv	1026	13	)	)	-RRB-
cord-347298-7kqrl3rv	1026	14	.	.	.
cord-347298-7kqrl3rv	1027	1	This	this	DT
cord-347298-7kqrl3rv	1027	2	is	be	VBZ
cord-347298-7kqrl3rv	1027	3	not	not	RB
cord-347298-7kqrl3rv	1027	4	particularly	particularly	RB
cord-347298-7kqrl3rv	1027	5	surprising	surprising	JJ
cord-347298-7kqrl3rv	1027	6	,	,	,
cord-347298-7kqrl3rv	1027	7	as	as	IN
cord-347298-7kqrl3rv	1027	8	these	these	DT
cord-347298-7kqrl3rv	1027	9	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1027	10	are	be	VBP
cord-347298-7kqrl3rv	1027	11	present	present	JJ
cord-347298-7kqrl3rv	1027	12	in	in	IN
cord-347298-7kqrl3rv	1027	13	most	most	JJS
cord-347298-7kqrl3rv	1027	14	biological	biological	JJ
cord-347298-7kqrl3rv	1027	15	fluids	fluid	NNS
cord-347298-7kqrl3rv	1027	16	and	and	CC
cord-347298-7kqrl3rv	1027	17	are	be	VBP
cord-347298-7kqrl3rv	1027	18	modulated	modulate	VBN
cord-347298-7kqrl3rv	1027	19	by	by	IN
cord-347298-7kqrl3rv	1027	20	the	the	DT
cord-347298-7kqrl3rv	1027	21	general	general	JJ
cord-347298-7kqrl3rv	1027	22	health	health	NN
cord-347298-7kqrl3rv	1027	23	status	status	NN
cord-347298-7kqrl3rv	1027	24	of	of	IN
cord-347298-7kqrl3rv	1027	25	the	the	DT
cord-347298-7kqrl3rv	1027	26	individual	individual	NN
cord-347298-7kqrl3rv	1027	27	.	.	.
cord-347298-7kqrl3rv	1028	1	Soluble	soluble	JJ
cord-347298-7kqrl3rv	1028	2	IL2	IL2	NNP
cord-347298-7kqrl3rv	1028	3	and	and	CC
cord-347298-7kqrl3rv	1028	4	IL6	IL6	NNP
cord-347298-7kqrl3rv	1028	5	receptors	receptor	NNS
cord-347298-7kqrl3rv	1028	6	,	,	,
cord-347298-7kqrl3rv	1028	7	molecules	molecule	NNS
cord-347298-7kqrl3rv	1028	8	that	that	WDT
cord-347298-7kqrl3rv	1028	9	modulate	modulate	VBP
cord-347298-7kqrl3rv	1028	10	the	the	DT
cord-347298-7kqrl3rv	1028	11	activity	activity	NN
cord-347298-7kqrl3rv	1028	12	of	of	IN
cord-347298-7kqrl3rv	1028	13	their	-PRON-	PRP$
cord-347298-7kqrl3rv	1028	14	respective	respective	JJ
cord-347298-7kqrl3rv	1028	15	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1028	16	,	,	,
cord-347298-7kqrl3rv	1028	17	have	have	VBP
cord-347298-7kqrl3rv	1028	18	also	also	RB
cord-347298-7kqrl3rv	1028	19	been	be	VBN
cord-347298-7kqrl3rv	1028	20	found	find	VBN
cord-347298-7kqrl3rv	1028	21	in	in	IN
cord-347298-7kqrl3rv	1028	22	seminal	seminal	JJ
cord-347298-7kqrl3rv	1028	23	plasma	plasma	NN
cord-347298-7kqrl3rv	1029	1	(	(	-LRB-
cord-347298-7kqrl3rv	1029	2	Huleihel	Huleihel	NNP
cord-347298-7kqrl3rv	1029	3	et	et	NNP
cord-347298-7kqrl3rv	1029	4	al	al	NNP
cord-347298-7kqrl3rv	1029	5	.	.	.
cord-347298-7kqrl3rv	1029	6	1999	1999	CD
cord-347298-7kqrl3rv	1029	7	)	)	-RRB-
cord-347298-7kqrl3rv	1029	8	.	.	.
cord-347298-7kqrl3rv	1030	1	Numerous	numerous	JJ
cord-347298-7kqrl3rv	1030	2	studies	study	NNS
cord-347298-7kqrl3rv	1030	3	have	have	VBP
cord-347298-7kqrl3rv	1030	4	shown	show	VBN
cord-347298-7kqrl3rv	1030	5	that	that	IN
cord-347298-7kqrl3rv	1030	6	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	1030	7	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1030	8	are	be	VBP
cord-347298-7kqrl3rv	1030	9	dramatically	dramatically	RB
cord-347298-7kqrl3rv	1030	10	elevated	elevate	VBN
cord-347298-7kqrl3rv	1030	11	in	in	IN
cord-347298-7kqrl3rv	1030	12	patients	patient	NNS
cord-347298-7kqrl3rv	1030	13	with	with	IN
cord-347298-7kqrl3rv	1030	14	inflammation	inflammation	NN
cord-347298-7kqrl3rv	1030	15	and/or	and/or	CC
cord-347298-7kqrl3rv	1030	16	leukocytospermia	leukocytospermia	NN
cord-347298-7kqrl3rv	1030	17	(	(	-LRB-
cord-347298-7kqrl3rv	1030	18	Eggert	Eggert	NNP
cord-347298-7kqrl3rv	1030	19	-	-	HYPH
cord-347298-7kqrl3rv	1030	20	Kruse	Kruse	NNP
cord-347298-7kqrl3rv	1030	21	et	et	NNP
cord-347298-7kqrl3rv	1030	22	al	al	NNP
cord-347298-7kqrl3rv	1030	23	.	.	.
cord-347298-7kqrl3rv	1031	1	2001	2001	CD
cord-347298-7kqrl3rv	1031	2	;	;	:
cord-347298-7kqrl3rv	1031	3	Krause	Krause	NNP
cord-347298-7kqrl3rv	1031	4	et	et	NNP
cord-347298-7kqrl3rv	1031	5	al	al	NNP
cord-347298-7kqrl3rv	1031	6	.	.	.
cord-347298-7kqrl3rv	1032	1	2003	2003	CD
cord-347298-7kqrl3rv	1032	2	;	;	:
cord-347298-7kqrl3rv	1032	3	Maegawa	Maegawa	NNP
cord-347298-7kqrl3rv	1032	4	et	et	NNP
cord-347298-7kqrl3rv	1032	5	al	al	NNP
cord-347298-7kqrl3rv	1032	6	.	.	.
cord-347298-7kqrl3rv	1033	1	2002	2002	CD
cord-347298-7kqrl3rv	1033	2	;	;	:
cord-347298-7kqrl3rv	1033	3	Miller	Miller	NNP
cord-347298-7kqrl3rv	1033	4	et	et	NNP
cord-347298-7kqrl3rv	1033	5	al	al	NNP
cord-347298-7kqrl3rv	1033	6	.	.	.
cord-347298-7kqrl3rv	1034	1	2002	2002	CD
cord-347298-7kqrl3rv	1034	2	;	;	:
cord-347298-7kqrl3rv	1034	3	Rajasekaran	Rajasekaran	NNP
cord-347298-7kqrl3rv	1034	4	et	et	FW
cord-347298-7kqrl3rv	1034	5	al	al	NNP
cord-347298-7kqrl3rv	1034	6	.	.	.
cord-347298-7kqrl3rv	1034	7	1996	1996	CD
cord-347298-7kqrl3rv	1034	8	)	)	-RRB-
cord-347298-7kqrl3rv	1034	9	.	.	.
cord-347298-7kqrl3rv	1035	1	However	however	RB
cord-347298-7kqrl3rv	1035	2	,	,	,
cord-347298-7kqrl3rv	1035	3	specific	specific	JJ
cord-347298-7kqrl3rv	1035	4	positive	positive	JJ
cord-347298-7kqrl3rv	1035	5	and	and	CC
cord-347298-7kqrl3rv	1035	6	negative	negative	JJ
cord-347298-7kqrl3rv	1035	7	associations	association	NNS
cord-347298-7kqrl3rv	1035	8	with	with	IN
cord-347298-7kqrl3rv	1035	9	other	other	JJ
cord-347298-7kqrl3rv	1035	10	forms	form	NNS
cord-347298-7kqrl3rv	1035	11	of	of	IN
cord-347298-7kqrl3rv	1035	12	infertility	infertility	NN
cord-347298-7kqrl3rv	1035	13	have	have	VBP
cord-347298-7kqrl3rv	1035	14	also	also	RB
cord-347298-7kqrl3rv	1035	15	been	be	VBN
cord-347298-7kqrl3rv	1035	16	reported	report	VBN
cord-347298-7kqrl3rv	1036	1	(	(	-LRB-
cord-347298-7kqrl3rv	1036	2	Eggert	Eggert	NNP
cord-347298-7kqrl3rv	1036	3	-	-	HYPH
cord-347298-7kqrl3rv	1036	4	Kruse	Kruse	NNP
cord-347298-7kqrl3rv	1036	5	et	et	NNP
cord-347298-7kqrl3rv	1036	6	al	al	NNP
cord-347298-7kqrl3rv	1036	7	.	.	.
cord-347298-7kqrl3rv	1037	1	2001	2001	CD
cord-347298-7kqrl3rv	1037	2	;	;	:
cord-347298-7kqrl3rv	1037	3	Gruschwitz	Gruschwitz	NNP
cord-347298-7kqrl3rv	1037	4	et	et	NNP
cord-347298-7kqrl3rv	1037	5	al	al	NNP
cord-347298-7kqrl3rv	1037	6	.	.	.
cord-347298-7kqrl3rv	1038	1	1996	1996	CD
cord-347298-7kqrl3rv	1039	1	;	;	:
cord-347298-7kqrl3rv	1039	2	Huleihel	Huleihel	NNP
cord-347298-7kqrl3rv	1039	3	et	et	NNP
cord-347298-7kqrl3rv	1039	4	al	al	NNP
cord-347298-7kqrl3rv	1039	5	.	.	.
cord-347298-7kqrl3rv	1040	1	1999	1999	CD
cord-347298-7kqrl3rv	1040	2	;	;	:
cord-347298-7kqrl3rv	1040	3	Loras	Loras	NNP
cord-347298-7kqrl3rv	1040	4	et	et	NNP
cord-347298-7kqrl3rv	1040	5	al	al	NNP
cord-347298-7kqrl3rv	1040	6	.	.	.
cord-347298-7kqrl3rv	1041	1	1999	1999	CD
cord-347298-7kqrl3rv	1041	2	;	;	:
cord-347298-7kqrl3rv	1041	3	Naz	Naz	NNP
cord-347298-7kqrl3rv	1041	4	and	and	CC
cord-347298-7kqrl3rv	1041	5	Evans	Evans	NNP
cord-347298-7kqrl3rv	1041	6	1998	1998	CD
cord-347298-7kqrl3rv	1041	7	)	)	-RRB-
cord-347298-7kqrl3rv	1041	8	.	.	.
cord-347298-7kqrl3rv	1042	1	Seminal	seminal	JJ
cord-347298-7kqrl3rv	1042	2	plasma	plasma	NN
cord-347298-7kqrl3rv	1042	3	has	have	VBZ
cord-347298-7kqrl3rv	1042	4	profoundly	profoundly	RB
cord-347298-7kqrl3rv	1042	5	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	1042	6	properties	property	NNS
cord-347298-7kqrl3rv	1042	7	,	,	,
cord-347298-7kqrl3rv	1042	8	as	as	IN
cord-347298-7kqrl3rv	1042	9	defined	define	VBN
cord-347298-7kqrl3rv	1042	10	by	by	IN
cord-347298-7kqrl3rv	1042	11	the	the	DT
cord-347298-7kqrl3rv	1042	12	ability	ability	NN
cord-347298-7kqrl3rv	1042	13	to	to	TO
cord-347298-7kqrl3rv	1042	14	inhibit	inhibit	VB
cord-347298-7kqrl3rv	1042	15	various	various	JJ
cord-347298-7kqrl3rv	1042	16	T	t	NN
cord-347298-7kqrl3rv	1042	17	cell	cell	NN
cord-347298-7kqrl3rv	1042	18	and	and	CC
cord-347298-7kqrl3rv	1042	19	NK	NK	NNP
cord-347298-7kqrl3rv	1042	20	cell	cell	NN
cord-347298-7kqrl3rv	1042	21	activities	activity	NNS
cord-347298-7kqrl3rv	1042	22	in	in	IN
cord-347298-7kqrl3rv	1042	23	vitro	vitro	FW
cord-347298-7kqrl3rv	1042	24	.	.	.
cord-347298-7kqrl3rv	1043	1	This	this	DT
cord-347298-7kqrl3rv	1043	2	inhibitory	inhibitory	JJ
cord-347298-7kqrl3rv	1043	3	activity	activity	NN
cord-347298-7kqrl3rv	1043	4	has	have	VBZ
cord-347298-7kqrl3rv	1043	5	been	be	VBN
cord-347298-7kqrl3rv	1043	6	attributed	attribute	VBN
cord-347298-7kqrl3rv	1043	7	to	to	IN
cord-347298-7kqrl3rv	1043	8	a	a	DT
cord-347298-7kqrl3rv	1043	9	number	number	NN
cord-347298-7kqrl3rv	1043	10	of	of	IN
cord-347298-7kqrl3rv	1043	11	seminal	seminal	JJ
cord-347298-7kqrl3rv	1043	12	factors	factor	NNS
cord-347298-7kqrl3rv	1043	13	,	,	,
cord-347298-7kqrl3rv	1043	14	including	include	VBG
cord-347298-7kqrl3rv	1043	15	prostasomes	prostasome	NNS
cord-347298-7kqrl3rv	1043	16	(	(	-LRB-
cord-347298-7kqrl3rv	1043	17	Kelly	Kelly	NNP
cord-347298-7kqrl3rv	1043	18	et	et	NNP
cord-347298-7kqrl3rv	1043	19	al	al	NNP
cord-347298-7kqrl3rv	1043	20	.	.	NNP
cord-347298-7kqrl3rv	1043	21	1991	1991	CD
cord-347298-7kqrl3rv	1043	22	)	)	-RRB-
cord-347298-7kqrl3rv	1043	23	,	,	,
cord-347298-7kqrl3rv	1043	24	oxidized	oxidize	VBN
cord-347298-7kqrl3rv	1043	25	polyamines	polyamine	NNS
cord-347298-7kqrl3rv	1043	26	(	(	-LRB-
cord-347298-7kqrl3rv	1043	27	Allen	Allen	NNP
cord-347298-7kqrl3rv	1043	28	and	and	CC
cord-347298-7kqrl3rv	1043	29	Roberts	Roberts	NNP
cord-347298-7kqrl3rv	1043	30	1986	1986	CD
cord-347298-7kqrl3rv	1043	31	)	)	-RRB-
cord-347298-7kqrl3rv	1043	32	,	,	,
cord-347298-7kqrl3rv	1043	33	prostaglandins	prostaglandin	NNS
cord-347298-7kqrl3rv	1043	34	of	of	IN
cord-347298-7kqrl3rv	1043	35	the	the	DT
cord-347298-7kqrl3rv	1043	36	E	E	NNP
cord-347298-7kqrl3rv	1043	37	series	series	NN
cord-347298-7kqrl3rv	1043	38	(	(	-LRB-
cord-347298-7kqrl3rv	1043	39	Skibinski	Skibinski	NNP
cord-347298-7kqrl3rv	1043	40	et	et	NNP
cord-347298-7kqrl3rv	1043	41	al	al	NNP
cord-347298-7kqrl3rv	1043	42	.	.	NNP
cord-347298-7kqrl3rv	1043	43	1992	1992	CD
cord-347298-7kqrl3rv	1043	44	)	)	-RRB-
cord-347298-7kqrl3rv	1043	45	,	,	,
cord-347298-7kqrl3rv	1043	46	nonspecific	nonspecific	JJ
cord-347298-7kqrl3rv	1043	47	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	1043	48	-	-	HYPH
cord-347298-7kqrl3rv	1043	49	suppressing	suppress	VBG
cord-347298-7kqrl3rv	1043	50	proteins	protein	NNS
cord-347298-7kqrl3rv	1043	51	(	(	-LRB-
cord-347298-7kqrl3rv	1043	52	Maccioni	Maccioni	NNP
cord-347298-7kqrl3rv	1043	53	et	et	NNP
cord-347298-7kqrl3rv	1043	54	al	al	NNP
cord-347298-7kqrl3rv	1043	55	.	.	NNP
cord-347298-7kqrl3rv	1043	56	2001	2001	CD
cord-347298-7kqrl3rv	1043	57	;	;	:
cord-347298-7kqrl3rv	1043	58	Veselský	Veselský	NNP
cord-347298-7kqrl3rv	1043	59	et	et	NNP
cord-347298-7kqrl3rv	1043	60	al	al	NNP
cord-347298-7kqrl3rv	1043	61	.	.	.
cord-347298-7kqrl3rv	1043	62	2002	2002	CD
cord-347298-7kqrl3rv	1043	63	)	)	-RRB-
cord-347298-7kqrl3rv	1043	64	,	,	,
cord-347298-7kqrl3rv	1043	65	and	and	CC
cord-347298-7kqrl3rv	1043	66	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	1043	67	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1043	68	(	(	-LRB-
cord-347298-7kqrl3rv	1043	69	Anderson	Anderson	NNP
cord-347298-7kqrl3rv	1043	70	et	et	NNP
cord-347298-7kqrl3rv	1043	71	al	al	NNP
cord-347298-7kqrl3rv	1043	72	.	.	.
cord-347298-7kqrl3rv	1044	1	1998	1998	CD
cord-347298-7kqrl3rv	1044	2	;	;	:
cord-347298-7kqrl3rv	1044	3	Huleihel	Huleihel	NNP
cord-347298-7kqrl3rv	1044	4	et	et	NNP
cord-347298-7kqrl3rv	1044	5	al	al	NNP
cord-347298-7kqrl3rv	1044	6	.	.	.
cord-347298-7kqrl3rv	1045	1	1999	1999	CD
cord-347298-7kqrl3rv	1045	2	;	;	:
cord-347298-7kqrl3rv	1045	3	Loras	Loras	NNP
cord-347298-7kqrl3rv	1045	4	et	et	NNP
cord-347298-7kqrl3rv	1045	5	al	al	NNP
cord-347298-7kqrl3rv	1045	6	.	.	.
cord-347298-7kqrl3rv	1046	1	1999	1999	CD
cord-347298-7kqrl3rv	1046	2	;	;	:
cord-347298-7kqrl3rv	1046	3	Miller	Miller	NNP
cord-347298-7kqrl3rv	1046	4	et	et	NNP
cord-347298-7kqrl3rv	1046	5	al	al	NNP
cord-347298-7kqrl3rv	1046	6	.	.	.
cord-347298-7kqrl3rv	1047	1	2002	2002	CD
cord-347298-7kqrl3rv	1047	2	;	;	:
cord-347298-7kqrl3rv	1047	3	Nocera	Nocera	NNP
cord-347298-7kqrl3rv	1047	4	and	and	CC
cord-347298-7kqrl3rv	1047	5	Chu	Chu	NNP
cord-347298-7kqrl3rv	1047	6	1993	1993	CD
cord-347298-7kqrl3rv	1047	7	;	;	:
cord-347298-7kqrl3rv	1047	8	Rajasekaran	Rajasekaran	NNP
cord-347298-7kqrl3rv	1047	9	et	et	FW
cord-347298-7kqrl3rv	1047	10	al	al	NNP
cord-347298-7kqrl3rv	1047	11	.	.	.
cord-347298-7kqrl3rv	1048	1	1996	1996	CD
cord-347298-7kqrl3rv	1048	2	;	;	:
cord-347298-7kqrl3rv	1048	3	Srivastava	Srivastava	NNP
cord-347298-7kqrl3rv	1048	4	et	et	NNP
cord-347298-7kqrl3rv	1048	5	al	al	NNP
cord-347298-7kqrl3rv	1048	6	.	.	.
cord-347298-7kqrl3rv	1048	7	1996	1996	CD
cord-347298-7kqrl3rv	1048	8	)	)	-RRB-
cord-347298-7kqrl3rv	1048	9	.	.	.
cord-347298-7kqrl3rv	1049	1	The	the	DT
cord-347298-7kqrl3rv	1049	2	main	main	JJ
cord-347298-7kqrl3rv	1049	3	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1049	4	with	with	IN
cord-347298-7kqrl3rv	1049	5	immunosuppressive	immunosuppressive	JJ
cord-347298-7kqrl3rv	1049	6	activity	activity	NN
cord-347298-7kqrl3rv	1049	7	in	in	IN
cord-347298-7kqrl3rv	1049	8	human	human	JJ
cord-347298-7kqrl3rv	1049	9	seminal	seminal	JJ
cord-347298-7kqrl3rv	1049	10	plasma	plasma	NN
cord-347298-7kqrl3rv	1049	11	are	be	VBP
cord-347298-7kqrl3rv	1049	12	TGF1	TGF1	NNP
cord-347298-7kqrl3rv	1049	13	,	,	,
cord-347298-7kqrl3rv	1049	14	TGF2	TGF2	NNP
cord-347298-7kqrl3rv	1049	15	,	,	,
cord-347298-7kqrl3rv	1049	16	IL10	IL10	NNP
cord-347298-7kqrl3rv	1049	17	,	,	,
cord-347298-7kqrl3rv	1049	18	and	and	CC
cord-347298-7kqrl3rv	1049	19	activin	activin	NNP
cord-347298-7kqrl3rv	1049	20	A.	A.	NNP
cord-347298-7kqrl3rv	1049	21	Immunosuppressives	Immunosuppressives	NNP
cord-347298-7kqrl3rv	1049	22	are	be	VBP
cord-347298-7kqrl3rv	1049	23	believed	believe	VBN
cord-347298-7kqrl3rv	1049	24	to	to	TO
cord-347298-7kqrl3rv	1049	25	play	play	VB
cord-347298-7kqrl3rv	1049	26	a	a	DT
cord-347298-7kqrl3rv	1049	27	role	role	NN
cord-347298-7kqrl3rv	1049	28	in	in	IN
cord-347298-7kqrl3rv	1049	29	preventing	prevent	VBG
cord-347298-7kqrl3rv	1049	30	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	1049	31	responses	response	NNS
cord-347298-7kqrl3rv	1049	32	against	against	IN
cord-347298-7kqrl3rv	1049	33	sperm	sperm	NN
cord-347298-7kqrl3rv	1049	34	autoantigens	autoantigen	NNS
cord-347298-7kqrl3rv	1049	35	in	in	IN
cord-347298-7kqrl3rv	1049	36	the	the	DT
cord-347298-7kqrl3rv	1049	37	male	male	JJ
cord-347298-7kqrl3rv	1049	38	and	and	CC
cord-347298-7kqrl3rv	1049	39	female	female	JJ
cord-347298-7kqrl3rv	1049	40	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1049	41	tracts	tract	NNS
cord-347298-7kqrl3rv	1049	42	Ochsenkühn	Ochsenkühn	NNP
cord-347298-7kqrl3rv	1049	43	et	et	NNP
cord-347298-7kqrl3rv	1049	44	al	al	NNP
cord-347298-7kqrl3rv	1049	45	.	.	.
cord-347298-7kqrl3rv	1049	46	2006	2006	CD
cord-347298-7kqrl3rv	1049	47	)	)	-RRB-
cord-347298-7kqrl3rv	1049	48	.	.	.
cord-347298-7kqrl3rv	1050	1	In	in	IN
cord-347298-7kqrl3rv	1050	2	the	the	DT
cord-347298-7kqrl3rv	1050	3	current	current	JJ
cord-347298-7kqrl3rv	1050	4	state	state	NN
cord-347298-7kqrl3rv	1050	5	of	of	IN
cord-347298-7kqrl3rv	1050	6	understanding	understanding	NN
cord-347298-7kqrl3rv	1050	7	of	of	IN
cord-347298-7kqrl3rv	1050	8	the	the	DT
cord-347298-7kqrl3rv	1050	9	interactions	interaction	NNS
cord-347298-7kqrl3rv	1050	10	between	between	IN
cord-347298-7kqrl3rv	1050	11	the	the	DT
cord-347298-7kqrl3rv	1050	12	male	male	JJ
cord-347298-7kqrl3rv	1050	13	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1050	14	tract	tract	NN
cord-347298-7kqrl3rv	1050	15	and	and	CC
cord-347298-7kqrl3rv	1050	16	the	the	DT
cord-347298-7kqrl3rv	1050	17	immune	immune	JJ
cord-347298-7kqrl3rv	1050	18	system	system	NN
cord-347298-7kqrl3rv	1050	19	,	,	,
cord-347298-7kqrl3rv	1050	20	many	many	JJ
cord-347298-7kqrl3rv	1050	21	questions	question	NNS
cord-347298-7kqrl3rv	1050	22	still	still	RB
cord-347298-7kqrl3rv	1050	23	remain	remain	VBP
cord-347298-7kqrl3rv	1050	24	.	.	.
cord-347298-7kqrl3rv	1051	1	Nonetheless	nonetheless	RB
cord-347298-7kqrl3rv	1051	2	,	,	,
cord-347298-7kqrl3rv	1051	3	it	-PRON-	PRP
cord-347298-7kqrl3rv	1051	4	is	be	VBZ
cord-347298-7kqrl3rv	1051	5	clear	clear	JJ
cord-347298-7kqrl3rv	1051	6	that	that	IN
cord-347298-7kqrl3rv	1051	7	the	the	DT
cord-347298-7kqrl3rv	1051	8	mammalian	mammalian	JJ
cord-347298-7kqrl3rv	1051	9	testis	testis	NN
cord-347298-7kqrl3rv	1051	10	in	in	IN
cord-347298-7kqrl3rv	1051	11	particular	particular	JJ
cord-347298-7kqrl3rv	1051	12	displays	display	VBZ
cord-347298-7kqrl3rv	1051	13	a	a	DT
cord-347298-7kqrl3rv	1051	14	special	special	JJ
cord-347298-7kqrl3rv	1051	15	,	,	,
cord-347298-7kqrl3rv	1051	16	if	if	IN
cord-347298-7kqrl3rv	1051	17	not	not	RB
cord-347298-7kqrl3rv	1051	18	unique	unique	JJ
cord-347298-7kqrl3rv	1051	19	,	,	,
cord-347298-7kqrl3rv	1051	20	relationship	relationship	NN
cord-347298-7kqrl3rv	1051	21	with	with	IN
cord-347298-7kqrl3rv	1051	22	the	the	DT
cord-347298-7kqrl3rv	1051	23	immune	immune	JJ
cord-347298-7kqrl3rv	1051	24	system	system	NN
cord-347298-7kqrl3rv	1051	25	,	,	,
cord-347298-7kqrl3rv	1051	26	involving	involve	VBG
cord-347298-7kqrl3rv	1051	27	distinctive	distinctive	JJ
cord-347298-7kqrl3rv	1051	28	cell	cell	NN
cord-347298-7kqrl3rv	1051	29	-	-	HYPH
cord-347298-7kqrl3rv	1051	30	cell	cell	NN
cord-347298-7kqrl3rv	1051	31	interactions	interaction	NNS
cord-347298-7kqrl3rv	1051	32	and	and	CC
cord-347298-7kqrl3rv	1051	33	shared	share	VBN
cord-347298-7kqrl3rv	1051	34	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1051	35	.	.	.
cord-347298-7kqrl3rv	1052	1	Recently	recently	RB
cord-347298-7kqrl3rv	1052	2	,	,	,
cord-347298-7kqrl3rv	1052	3	microarray	microarray	NN
cord-347298-7kqrl3rv	1052	4	analysis	analysis	NN
cord-347298-7kqrl3rv	1052	5	of	of	IN
cord-347298-7kqrl3rv	1052	6	testicular	testicular	JJ
cord-347298-7kqrl3rv	1052	7	gene	gene	NN
cord-347298-7kqrl3rv	1052	8	expression	expression	NN
cord-347298-7kqrl3rv	1052	9	signatures	signature	NNS
cord-347298-7kqrl3rv	1052	10	in	in	IN
cord-347298-7kqrl3rv	1052	11	human	human	JJ
cord-347298-7kqrl3rv	1052	12	spermatogenic	spermatogenic	NN
cord-347298-7kqrl3rv	1052	13	failure	failure	NN
cord-347298-7kqrl3rv	1052	14	were	be	VBD
cord-347298-7kqrl3rv	1052	15	found	find	VBN
cord-347298-7kqrl3rv	1052	16	to	to	TO
cord-347298-7kqrl3rv	1052	17	correspond	correspond	VB
cord-347298-7kqrl3rv	1052	18	with	with	IN
cord-347298-7kqrl3rv	1052	19	gene	gene	NN
cord-347298-7kqrl3rv	1052	20	sets	set	NNS
cord-347298-7kqrl3rv	1052	21	usually	usually	RB
cord-347298-7kqrl3rv	1052	22	associated	associate	VBN
cord-347298-7kqrl3rv	1052	23	with	with	IN
cord-347298-7kqrl3rv	1052	24	inflammation	inflammation	NN
cord-347298-7kqrl3rv	1052	25	and	and	CC
cord-347298-7kqrl3rv	1052	26	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1052	27	disease	disease	NN
cord-347298-7kqrl3rv	1053	1	(	(	-LRB-
cord-347298-7kqrl3rv	1053	2	Spiess	Spiess	NNP
cord-347298-7kqrl3rv	1053	3	et	et	FW
cord-347298-7kqrl3rv	1053	4	al	al	NNP
cord-347298-7kqrl3rv	1053	5	.	.	NNP
cord-347298-7kqrl3rv	1053	6	2007	2007	CD
cord-347298-7kqrl3rv	1053	7	)	)	-RRB-
cord-347298-7kqrl3rv	1053	8	.	.	.
cord-347298-7kqrl3rv	1054	1	This	this	DT
cord-347298-7kqrl3rv	1054	2	relationship	relationship	NN
cord-347298-7kqrl3rv	1054	3	between	between	IN
cord-347298-7kqrl3rv	1054	4	reproduction	reproduction	NN
cord-347298-7kqrl3rv	1054	5	and	and	CC
cord-347298-7kqrl3rv	1054	6	immunology	immunology	NN
cord-347298-7kqrl3rv	1054	7	impacts	impact	NNS
cord-347298-7kqrl3rv	1054	8	upon	upon	IN
cord-347298-7kqrl3rv	1054	9	normal	normal	JJ
cord-347298-7kqrl3rv	1054	10	function	function	NN
cord-347298-7kqrl3rv	1054	11	,	,	,
cord-347298-7kqrl3rv	1054	12	since	since	IN
cord-347298-7kqrl3rv	1054	13	perturbations	perturbation	NNS
cord-347298-7kqrl3rv	1054	14	in	in	IN
cord-347298-7kqrl3rv	1054	15	one	one	CD
cord-347298-7kqrl3rv	1054	16	system	system	NN
cord-347298-7kqrl3rv	1054	17	caused	cause	VBN
cord-347298-7kqrl3rv	1054	18	by	by	IN
cord-347298-7kqrl3rv	1054	19	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1054	20	will	will	MD
cord-347298-7kqrl3rv	1054	21	almost	almost	RB
cord-347298-7kqrl3rv	1054	22	certainly	certainly	RB
cord-347298-7kqrl3rv	1054	23	impinge	impinge	VB
cord-347298-7kqrl3rv	1054	24	upon	upon	IN
cord-347298-7kqrl3rv	1054	25	the	the	DT
cord-347298-7kqrl3rv	1054	26	other	other	JJ
cord-347298-7kqrl3rv	1054	27	system	system	NN
cord-347298-7kqrl3rv	1054	28	.	.	.
cord-347298-7kqrl3rv	1055	1	This	this	DT
cord-347298-7kqrl3rv	1055	2	extends	extend	VBZ
cord-347298-7kqrl3rv	1055	3	into	into	IN
cord-347298-7kqrl3rv	1055	4	the	the	DT
cord-347298-7kqrl3rv	1055	5	characteristic	characteristic	JJ
cord-347298-7kqrl3rv	1055	6	responses	response	NNS
cord-347298-7kqrl3rv	1055	7	of	of	IN
cord-347298-7kqrl3rv	1055	8	the	the	DT
cord-347298-7kqrl3rv	1055	9	testis	testis	NN
cord-347298-7kqrl3rv	1055	10	to	to	IN
cord-347298-7kqrl3rv	1055	11	toxins	toxin	NNS
cord-347298-7kqrl3rv	1055	12	and	and	CC
cord-347298-7kqrl3rv	1055	13	various	various	JJ
cord-347298-7kqrl3rv	1055	14	pathologies	pathology	NNS
cord-347298-7kqrl3rv	1055	15	(	(	-LRB-
cord-347298-7kqrl3rv	1055	16	Figure	figure	NN
cord-347298-7kqrl3rv	1055	17	5	5	CD
cord-347298-7kqrl3rv	1055	18	)	)	-RRB-
cord-347298-7kqrl3rv	1055	19	.	.	.
cord-347298-7kqrl3rv	1056	1	The	the	DT
cord-347298-7kqrl3rv	1056	2	complexity	complexity	NN
cord-347298-7kqrl3rv	1056	3	and	and	CC
cord-347298-7kqrl3rv	1056	4	potential	potential	JJ
cord-347298-7kqrl3rv	1056	5	consequences	consequence	NNS
cord-347298-7kqrl3rv	1056	6	of	of	IN
cord-347298-7kqrl3rv	1056	7	these	these	DT
cord-347298-7kqrl3rv	1056	8	interactions	interaction	NNS
cord-347298-7kqrl3rv	1056	9	may	may	MD
cord-347298-7kqrl3rv	1056	10	be	be	VB
cord-347298-7kqrl3rv	1056	11	appreciated	appreciate	VBN
cord-347298-7kqrl3rv	1056	12	by	by	IN
cord-347298-7kqrl3rv	1056	13	consideration	consideration	NN
cord-347298-7kqrl3rv	1056	14	of	of	IN
cord-347298-7kqrl3rv	1056	15	the	the	DT
cord-347298-7kqrl3rv	1056	16	following	follow	VBG
cord-347298-7kqrl3rv	1056	17	propositions	proposition	NNS
cord-347298-7kqrl3rv	1056	18	:	:	:
cord-347298-7kqrl3rv	1057	1	1	1	LS
cord-347298-7kqrl3rv	1057	2	.	.	.
cord-347298-7kqrl3rv	1058	1	If	if	IN
cord-347298-7kqrl3rv	1058	2	leukocytes	leukocyte	NNS
cord-347298-7kqrl3rv	1058	3	play	play	VBP
cord-347298-7kqrl3rv	1058	4	a	a	DT
cord-347298-7kqrl3rv	1058	5	role	role	NN
cord-347298-7kqrl3rv	1058	6	in	in	IN
cord-347298-7kqrl3rv	1058	7	maintaining	maintain	VBG
cord-347298-7kqrl3rv	1058	8	normal	normal	JJ
cord-347298-7kqrl3rv	1058	9	testicular	testicular	JJ
cord-347298-7kqrl3rv	1058	10	function	function	NN
cord-347298-7kqrl3rv	1058	11	,	,	,
cord-347298-7kqrl3rv	1058	12	then	then	RB
cord-347298-7kqrl3rv	1058	13	drugs	drug	NNS
cord-347298-7kqrl3rv	1058	14	and	and	CC
cord-347298-7kqrl3rv	1058	15	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1058	16	that	that	WDT
cord-347298-7kqrl3rv	1058	17	reduce	reduce	VBP
cord-347298-7kqrl3rv	1058	18	macrophage	macrophage	NN
cord-347298-7kqrl3rv	1058	19	and	and	CC
cord-347298-7kqrl3rv	1058	20	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	1058	21	function	function	NN
cord-347298-7kqrl3rv	1058	22	or	or	CC
cord-347298-7kqrl3rv	1058	23	numbers	number	NNS
cord-347298-7kqrl3rv	1058	24	may	may	MD
cord-347298-7kqrl3rv	1058	25	also	also	RB
cord-347298-7kqrl3rv	1058	26	have	have	VB
cord-347298-7kqrl3rv	1058	27	an	an	DT
cord-347298-7kqrl3rv	1058	28	indirect	indirect	JJ
cord-347298-7kqrl3rv	1058	29	effect	effect	NN
cord-347298-7kqrl3rv	1058	30	on	on	IN
cord-347298-7kqrl3rv	1058	31	testicular	testicular	JJ
cord-347298-7kqrl3rv	1058	32	function	function	NN
cord-347298-7kqrl3rv	1058	33	.	.	.
cord-347298-7kqrl3rv	1059	1	The	the	DT
cord-347298-7kqrl3rv	1059	2	effect	effect	NN
cord-347298-7kqrl3rv	1059	3	of	of	IN
cord-347298-7kqrl3rv	1059	4	dichloromethylene	dichloromethylene	NN
cord-347298-7kqrl3rv	1059	5	diphosphonate	diphosphonate	NN
cord-347298-7kqrl3rv	1059	6	on	on	IN
cord-347298-7kqrl3rv	1059	7	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	1059	8	in	in	IN
cord-347298-7kqrl3rv	1059	9	the	the	DT
cord-347298-7kqrl3rv	1059	10	rat	rat	NN
cord-347298-7kqrl3rv	1059	11	provides	provide	VBZ
cord-347298-7kqrl3rv	1059	12	a	a	DT
cord-347298-7kqrl3rv	1059	13	good	good	JJ
cord-347298-7kqrl3rv	1059	14	experimental	experimental	JJ
cord-347298-7kqrl3rv	1059	15	example	example	NN
cord-347298-7kqrl3rv	1059	16	of	of	IN
cord-347298-7kqrl3rv	1059	17	this	this	DT
cord-347298-7kqrl3rv	1059	18	possibility	possibility	NN
cord-347298-7kqrl3rv	1059	19	,	,	,
cord-347298-7kqrl3rv	1059	20	by	by	IN
cord-347298-7kqrl3rv	1059	21	demonstrating	demonstrate	VBG
cord-347298-7kqrl3rv	1059	22	that	that	IN
cord-347298-7kqrl3rv	1059	23	the	the	DT
cord-347298-7kqrl3rv	1059	24	loss	loss	NN
cord-347298-7kqrl3rv	1059	25	of	of	IN
cord-347298-7kqrl3rv	1059	26	functioning	function	VBG
cord-347298-7kqrl3rv	1059	27	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	1059	28	leads	lead	VBZ
cord-347298-7kqrl3rv	1059	29	to	to	IN
cord-347298-7kqrl3rv	1059	30	a	a	DT
cord-347298-7kqrl3rv	1059	31	decline	decline	NN
cord-347298-7kqrl3rv	1059	32	in	in	IN
cord-347298-7kqrl3rv	1059	33	androgen	androgen	NN
cord-347298-7kqrl3rv	1059	34	levels	level	NNS
cord-347298-7kqrl3rv	1059	35	and	and	CC
cord-347298-7kqrl3rv	1059	36	retarded	retarded	JJ
cord-347298-7kqrl3rv	1059	37	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	1059	38	cell	cell	NN
cord-347298-7kqrl3rv	1059	39	development	development	NN
cord-347298-7kqrl3rv	1059	40	Gaytan	Gaytan	NNP
cord-347298-7kqrl3rv	1059	41	et	et	NNP
cord-347298-7kqrl3rv	1059	42	al	al	NNP
cord-347298-7kqrl3rv	1059	43	.	.	NNP
cord-347298-7kqrl3rv	1059	44	1994a	1994a	CD
cord-347298-7kqrl3rv	1059	45	)	)	-RRB-
cord-347298-7kqrl3rv	1059	46	.	.	.
cord-347298-7kqrl3rv	1060	1	Inhibition	inhibition	NN
cord-347298-7kqrl3rv	1060	2	of	of	IN
cord-347298-7kqrl3rv	1060	3	macrophage	macrophage	NN
cord-347298-7kqrl3rv	1060	4	and	and	CC
cord-347298-7kqrl3rv	1060	5	lymphocyte	lymphocyte	NN
cord-347298-7kqrl3rv	1060	6	functions	function	NNS
cord-347298-7kqrl3rv	1060	7	or	or	CC
cord-347298-7kqrl3rv	1060	8	numbers	number	NNS
cord-347298-7kqrl3rv	1060	9	may	may	MD
cord-347298-7kqrl3rv	1060	10	also	also	RB
cord-347298-7kqrl3rv	1060	11	compromise	compromise	VB
cord-347298-7kqrl3rv	1060	12	the	the	DT
cord-347298-7kqrl3rv	1060	13	immune	immune	NN
cord-347298-7kqrl3rv	1060	14	-	-	HYPH
cord-347298-7kqrl3rv	1060	15	privileged	privileged	JJ
cord-347298-7kqrl3rv	1060	16	status	status	NN
cord-347298-7kqrl3rv	1060	17	of	of	IN
cord-347298-7kqrl3rv	1060	18	the	the	DT
cord-347298-7kqrl3rv	1060	19	testis	testis	NN
cord-347298-7kqrl3rv	1060	20	,	,	,
cord-347298-7kqrl3rv	1060	21	potentially	potentially	RB
cord-347298-7kqrl3rv	1060	22	leading	lead	VBG
cord-347298-7kqrl3rv	1060	23	to	to	IN
cord-347298-7kqrl3rv	1060	24	testicular	testicular	JJ
cord-347298-7kqrl3rv	1060	25	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1060	26	disease	disease	NN
cord-347298-7kqrl3rv	1060	27	.	.	.
cord-347298-7kqrl3rv	1061	1	A	a	DT
cord-347298-7kqrl3rv	1061	2	related	related	JJ
cord-347298-7kqrl3rv	1061	3	subset	subset	NN
cord-347298-7kqrl3rv	1061	4	would	would	MD
cord-347298-7kqrl3rv	1061	5	involve	involve	VB
cord-347298-7kqrl3rv	1061	6	chemicals	chemical	NNS
cord-347298-7kqrl3rv	1061	7	that	that	WDT
cord-347298-7kqrl3rv	1061	8	have	have	VBP
cord-347298-7kqrl3rv	1061	9	direct	direct	JJ
cord-347298-7kqrl3rv	1061	10	action	action	NN
cord-347298-7kqrl3rv	1061	11	on	on	IN
cord-347298-7kqrl3rv	1061	12	both	both	CC
cord-347298-7kqrl3rv	1061	13	the	the	DT
cord-347298-7kqrl3rv	1061	14	immune	immune	JJ
cord-347298-7kqrl3rv	1061	15	system	system	NN
cord-347298-7kqrl3rv	1061	16	and	and	CC
cord-347298-7kqrl3rv	1061	17	testicular	testicular	JJ
cord-347298-7kqrl3rv	1061	18	function	function	NN
cord-347298-7kqrl3rv	1061	19	,	,	,
cord-347298-7kqrl3rv	1061	20	such	such	JJ
cord-347298-7kqrl3rv	1061	21	as	as	IN
cord-347298-7kqrl3rv	1061	22	cyclosporin	cyclosporin	NN
cord-347298-7kqrl3rv	1061	23	and	and	CC
cord-347298-7kqrl3rv	1061	24	cyclophosphamide	cyclophosphamide	NN
cord-347298-7kqrl3rv	1061	25	(	(	-LRB-
cord-347298-7kqrl3rv	1061	26	Cavallini	Cavallini	NNP
cord-347298-7kqrl3rv	1061	27	et	et	NNP
cord-347298-7kqrl3rv	1061	28	al	al	NNP
cord-347298-7kqrl3rv	1061	29	.	.	NNP
cord-347298-7kqrl3rv	1061	30	1990	1990	CD
cord-347298-7kqrl3rv	1061	31	;	;	.
cord-347298-7kqrl3rv	1062	1	Meistrich	Meistrich	NNP
cord-347298-7kqrl3rv	1062	2	1984	1984	CD
cord-347298-7kqrl3rv	1062	3	;	;	:
cord-347298-7kqrl3rv	1062	4	Seethalakshmi	Seethalakshmi	NNP
cord-347298-7kqrl3rv	1062	5	et	et	FW
cord-347298-7kqrl3rv	1062	6	al	al	NNP
cord-347298-7kqrl3rv	1062	7	.	.	NNP
cord-347298-7kqrl3rv	1062	8	1990	1990	CD
cord-347298-7kqrl3rv	1062	9	;	;	:
cord-347298-7kqrl3rv	1062	10	Wetzels	Wetzels	NNP
cord-347298-7kqrl3rv	1062	11	2004	2004	CD
cord-347298-7kqrl3rv	1062	12	)	)	-RRB-
cord-347298-7kqrl3rv	1062	13	,	,	,
cord-347298-7kqrl3rv	1062	14	which	which	WDT
cord-347298-7kqrl3rv	1062	15	are	be	VBP
cord-347298-7kqrl3rv	1062	16	commonly	commonly	RB
cord-347298-7kqrl3rv	1062	17	used	use	VBN
cord-347298-7kqrl3rv	1062	18	to	to	TO
cord-347298-7kqrl3rv	1062	19	suppress	suppress	VB
cord-347298-7kqrl3rv	1062	20	graft	graft	NN
cord-347298-7kqrl3rv	1062	21	rejection	rejection	NN
cord-347298-7kqrl3rv	1062	22	response	response	NN
cord-347298-7kqrl3rv	1062	23	and	and	CC
cord-347298-7kqrl3rv	1062	24	in	in	IN
cord-347298-7kqrl3rv	1062	25	the	the	DT
cord-347298-7kqrl3rv	1062	26	treatment	treatment	NN
cord-347298-7kqrl3rv	1062	27	of	of	IN
cord-347298-7kqrl3rv	1062	28	some	some	DT
cord-347298-7kqrl3rv	1062	29	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1062	30	diseases	disease	NNS
cord-347298-7kqrl3rv	1062	31	.	.	.
cord-347298-7kqrl3rv	1063	1	fere	fere	NNP
cord-347298-7kqrl3rv	1063	2	with	with	IN
cord-347298-7kqrl3rv	1063	3	normal	normal	JJ
cord-347298-7kqrl3rv	1063	4	testicular	testicular	JJ
cord-347298-7kqrl3rv	1063	5	function	function	NN
cord-347298-7kqrl3rv	1063	6	.	.	.
cord-347298-7kqrl3rv	1064	1	The	the	DT
cord-347298-7kqrl3rv	1064	2	serious	serious	JJ
cord-347298-7kqrl3rv	1064	3	consequences	consequence	NNS
cord-347298-7kqrl3rv	1064	4	for	for	IN
cord-347298-7kqrl3rv	1064	5	testicular	testicular	JJ
cord-347298-7kqrl3rv	1064	6	function	function	NN
cord-347298-7kqrl3rv	1064	7	associated	associate	VBN
cord-347298-7kqrl3rv	1064	8	with	with	IN
cord-347298-7kqrl3rv	1064	9	immune	immune	JJ
cord-347298-7kqrl3rv	1064	10	activation	activation	NN
cord-347298-7kqrl3rv	1064	11	and	and	CC
cord-347298-7kqrl3rv	1064	12	inflammation	inflammation	NN
cord-347298-7kqrl3rv	1064	13	are	be	VBP
cord-347298-7kqrl3rv	1064	14	illustrated	illustrate	VBN
cord-347298-7kqrl3rv	1064	15	by	by	IN
cord-347298-7kqrl3rv	1064	16	the	the	DT
cord-347298-7kqrl3rv	1064	17	experimental	experimental	JJ
cord-347298-7kqrl3rv	1064	18	model	model	NN
cord-347298-7kqrl3rv	1064	19	of	of	IN
cord-347298-7kqrl3rv	1064	20	LPS	LPS	NNP
cord-347298-7kqrl3rv	1064	21	administration	administration	NN
cord-347298-7kqrl3rv	1064	22	,	,	,
cord-347298-7kqrl3rv	1064	23	which	which	WDT
cord-347298-7kqrl3rv	1064	24	leads	lead	VBZ
cord-347298-7kqrl3rv	1064	25	to	to	IN
cord-347298-7kqrl3rv	1064	26	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	1064	27	cell	cell	NN
cord-347298-7kqrl3rv	1064	28	dysfunction	dysfunction	NN
cord-347298-7kqrl3rv	1064	29	and	and	CC
cord-347298-7kqrl3rv	1064	30	testicular	testicular	JJ
cord-347298-7kqrl3rv	1064	31	failure	failure	NN
cord-347298-7kqrl3rv	1064	32	(	(	-LRB-
cord-347298-7kqrl3rv	1064	33	Christeff	Christeff	NNP
cord-347298-7kqrl3rv	1064	34	et	et	FW
cord-347298-7kqrl3rv	1064	35	al	al	NNP
cord-347298-7kqrl3rv	1064	36	.	.	NNP
cord-347298-7kqrl3rv	1064	37	1987	1987	CD
cord-347298-7kqrl3rv	1064	38	;	;	:
cord-347298-7kqrl3rv	1064	39	Wallgren	Wallgren	NNP
cord-347298-7kqrl3rv	1064	40	et	et	NNP
cord-347298-7kqrl3rv	1064	41	al	al	NNP
cord-347298-7kqrl3rv	1064	42	.	.	NNP
cord-347298-7kqrl3rv	1064	43	1993	1993	CD
cord-347298-7kqrl3rv	1064	44	;	;	.
cord-347298-7kqrl3rv	1065	1	O'Bryan	O'Bryan	NNP
cord-347298-7kqrl3rv	1065	2	et	et	NNP
cord-347298-7kqrl3rv	1065	3	al	al	NNP
cord-347298-7kqrl3rv	1065	4	.	.	NNP
cord-347298-7kqrl3rv	1065	5	2000b	2000b	CD
cord-347298-7kqrl3rv	1065	6	)	)	-RRB-
cord-347298-7kqrl3rv	1065	7	.	.	.
cord-347298-7kqrl3rv	1066	1	Any	any	DT
cord-347298-7kqrl3rv	1066	2	drug	drug	NN
cord-347298-7kqrl3rv	1066	3	or	or	CC
cord-347298-7kqrl3rv	1066	4	toxicant	toxicant	NN
cord-347298-7kqrl3rv	1066	5	that	that	WDT
cord-347298-7kqrl3rv	1066	6	induces	induce	VBZ
cord-347298-7kqrl3rv	1066	7	macrophage	macrophage	NN
cord-347298-7kqrl3rv	1066	8	activation	activation	NN
cord-347298-7kqrl3rv	1066	9	(	(	-LRB-
cord-347298-7kqrl3rv	1066	10	e.g.	e.g.	RB
cord-347298-7kqrl3rv	1066	11	,	,	,
cord-347298-7kqrl3rv	1066	12	bacterial	bacterial	JJ
cord-347298-7kqrl3rv	1066	13	toxins	toxin	NNS
cord-347298-7kqrl3rv	1066	14	,	,	,
cord-347298-7kqrl3rv	1066	15	carbon	carbon	NN
cord-347298-7kqrl3rv	1066	16	monoxide	monoxide	NN
cord-347298-7kqrl3rv	1066	17	,	,	,
cord-347298-7kqrl3rv	1066	18	sulfur	sulfur	NN
cord-347298-7kqrl3rv	1066	19	dioxide	dioxide	NN
cord-347298-7kqrl3rv	1066	20	)	)	-RRB-
cord-347298-7kqrl3rv	1066	21	has	have	VBZ
cord-347298-7kqrl3rv	1066	22	the	the	DT
cord-347298-7kqrl3rv	1066	23	potential	potential	NN
cord-347298-7kqrl3rv	1066	24	to	to	TO
cord-347298-7kqrl3rv	1066	25	induce	induce	VB
cord-347298-7kqrl3rv	1066	26	testicular	testicular	JJ
cord-347298-7kqrl3rv	1066	27	production	production	NN
cord-347298-7kqrl3rv	1066	28	of	of	IN
cord-347298-7kqrl3rv	1066	29	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	1066	30	cytokines	cytokine	NNS
cord-347298-7kqrl3rv	1066	31	,	,	,
cord-347298-7kqrl3rv	1066	32	such	such	JJ
cord-347298-7kqrl3rv	1066	33	as	as	IN
cord-347298-7kqrl3rv	1066	34	IL1	IL1	NNP
cord-347298-7kqrl3rv	1066	35	,	,	,
cord-347298-7kqrl3rv	1066	36	TNF	TNF	NNP
cord-347298-7kqrl3rv	1066	37	,	,	,
cord-347298-7kqrl3rv	1066	38	and	and	CC
cord-347298-7kqrl3rv	1066	39	IFN	IFN	NNP
cord-347298-7kqrl3rv	1066	40	,	,	,
cord-347298-7kqrl3rv	1066	41	as	as	RB
cord-347298-7kqrl3rv	1066	42	well	well	RB
cord-347298-7kqrl3rv	1066	43	as	as	IN
cord-347298-7kqrl3rv	1066	44	ROS	ROS	NNP
cord-347298-7kqrl3rv	1066	45	,	,	,
cord-347298-7kqrl3rv	1066	46	which	which	WDT
cord-347298-7kqrl3rv	1066	47	may	may	MD
cord-347298-7kqrl3rv	1066	48	interfere	interfere	VB
cord-347298-7kqrl3rv	1066	49	with	with	IN
cord-347298-7kqrl3rv	1066	50	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	1066	51	cell	cell	NN
cord-347298-7kqrl3rv	1066	52	function	function	NN
cord-347298-7kqrl3rv	1066	53	and	and	CC
cord-347298-7kqrl3rv	1066	54	Androgen	Androgen	NNP
cord-347298-7kqrl3rv	1066	55	deficiency	deficiency	NN
cord-347298-7kqrl3rv	1067	1	Figure	figure	NN
cord-347298-7kqrl3rv	1067	2	5	5	CD
cord-347298-7kqrl3rv	1067	3	Model	model	NN
cord-347298-7kqrl3rv	1067	4	of	of	IN
cord-347298-7kqrl3rv	1067	5	toxicant	toxicant	NN
cord-347298-7kqrl3rv	1067	6	actions	action	NNS
cord-347298-7kqrl3rv	1067	7	and	and	CC
cord-347298-7kqrl3rv	1067	8	potential	potential	JJ
cord-347298-7kqrl3rv	1067	9	immunological	immunological	JJ
cord-347298-7kqrl3rv	1067	10	consequences	consequence	NNS
cord-347298-7kqrl3rv	1067	11	in	in	IN
cord-347298-7kqrl3rv	1067	12	the	the	DT
cord-347298-7kqrl3rv	1067	13	testis	testis	NN
cord-347298-7kqrl3rv	1067	14	.	.	.
cord-347298-7kqrl3rv	1068	1	Toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1068	2	may	may	MD
cord-347298-7kqrl3rv	1068	3	damage	damage	VB
cord-347298-7kqrl3rv	1068	4	or	or	CC
cord-347298-7kqrl3rv	1068	5	alter	alter	VB
cord-347298-7kqrl3rv	1068	6	the	the	DT
cord-347298-7kqrl3rv	1068	7	function	function	NN
cord-347298-7kqrl3rv	1068	8	of	of	IN
cord-347298-7kqrl3rv	1068	9	somatic	somatic	JJ
cord-347298-7kqrl3rv	1068	10	cells	cell	NNS
cord-347298-7kqrl3rv	1068	11	(	(	-LRB-
cord-347298-7kqrl3rv	1068	12	in	in	IN
cord-347298-7kqrl3rv	1068	13	particular	particular	JJ
cord-347298-7kqrl3rv	1068	14	the	the	DT
cord-347298-7kqrl3rv	1068	15	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	1068	16	and	and	CC
cord-347298-7kqrl3rv	1068	17	Leydig	Leydig	NNP
cord-347298-7kqrl3rv	1068	18	cells	cell	NNS
cord-347298-7kqrl3rv	1068	19	)	)	-RRB-
cord-347298-7kqrl3rv	1068	20	,	,	,
cord-347298-7kqrl3rv	1068	21	immune	immune	JJ
cord-347298-7kqrl3rv	1068	22	cells	cell	NNS
cord-347298-7kqrl3rv	1068	23	,	,	,
cord-347298-7kqrl3rv	1068	24	or	or	CC
cord-347298-7kqrl3rv	1068	25	germ	germ	NN
cord-347298-7kqrl3rv	1068	26	cells	cell	NNS
cord-347298-7kqrl3rv	1068	27	,	,	,
cord-347298-7kqrl3rv	1068	28	thereby	thereby	RB
cord-347298-7kqrl3rv	1068	29	inhibiting	inhibit	VBG
cord-347298-7kqrl3rv	1068	30	androgen	androgen	NN
cord-347298-7kqrl3rv	1068	31	production	production	NN
cord-347298-7kqrl3rv	1068	32	and	and	CC
cord-347298-7kqrl3rv	1068	33	spermatogenesis	spermatogenesis	NN
cord-347298-7kqrl3rv	1068	34	,	,	,
cord-347298-7kqrl3rv	1068	35	leading	lead	VBG
cord-347298-7kqrl3rv	1068	36	to	to	IN
cord-347298-7kqrl3rv	1068	37	increased	increase	VBN
cord-347298-7kqrl3rv	1068	38	germ	germ	NN
cord-347298-7kqrl3rv	1068	39	cell	cell	NN
cord-347298-7kqrl3rv	1068	40	death	death	NN
cord-347298-7kqrl3rv	1068	41	.	.	.
cord-347298-7kqrl3rv	1069	1	This	this	DT
cord-347298-7kqrl3rv	1069	2	damage	damage	NN
cord-347298-7kqrl3rv	1069	3	may	may	MD
cord-347298-7kqrl3rv	1069	4	lead	lead	VB
cord-347298-7kqrl3rv	1069	5	to	to	IN
cord-347298-7kqrl3rv	1069	6	an	an	DT
cord-347298-7kqrl3rv	1069	7	overt	overt	JJ
cord-347298-7kqrl3rv	1069	8	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	1069	9	event	event	NN
cord-347298-7kqrl3rv	1069	10	(	(	-LRB-
cord-347298-7kqrl3rv	1069	11	orchitis	orchitis	NN
cord-347298-7kqrl3rv	1069	12	)	)	-RRB-
cord-347298-7kqrl3rv	1069	13	through	through	IN
cord-347298-7kqrl3rv	1069	14	activation	activation	NN
cord-347298-7kqrl3rv	1069	15	of	of	IN
cord-347298-7kqrl3rv	1069	16	the	the	DT
cord-347298-7kqrl3rv	1069	17	proinflammatory	proinflammatory	JJ
cord-347298-7kqrl3rv	1069	18	activities	activity	NNS
cord-347298-7kqrl3rv	1069	19	of	of	IN
cord-347298-7kqrl3rv	1069	20	local	local	JJ
cord-347298-7kqrl3rv	1069	21	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	1069	22	,	,	,
cord-347298-7kqrl3rv	1069	23	which	which	WDT
cord-347298-7kqrl3rv	1069	24	may	may	MD
cord-347298-7kqrl3rv	1069	25	exacerbate	exacerbate	VB
cord-347298-7kqrl3rv	1069	26	or	or	CC
cord-347298-7kqrl3rv	1069	27	prolong	prolong	VB
cord-347298-7kqrl3rv	1069	28	the	the	DT
cord-347298-7kqrl3rv	1069	29	testicular	testicular	JJ
cord-347298-7kqrl3rv	1069	30	dysfunction	dysfunction	NN
cord-347298-7kqrl3rv	1069	31	.	.	.
cord-347298-7kqrl3rv	1070	1	These	these	DT
cord-347298-7kqrl3rv	1070	2	events	event	NNS
cord-347298-7kqrl3rv	1070	3	may	may	MD
cord-347298-7kqrl3rv	1070	4	be	be	VB
cord-347298-7kqrl3rv	1070	5	followed	follow	VBN
cord-347298-7kqrl3rv	1070	6	by	by	IN
cord-347298-7kqrl3rv	1070	7	a	a	DT
cord-347298-7kqrl3rv	1070	8	full	full	JJ
cord-347298-7kqrl3rv	1070	9	or	or	CC
cord-347298-7kqrl3rv	1070	10	partial	partial	JJ
cord-347298-7kqrl3rv	1070	11	recovery	recovery	NN
cord-347298-7kqrl3rv	1070	12	of	of	IN
cord-347298-7kqrl3rv	1070	13	normal	normal	JJ
cord-347298-7kqrl3rv	1070	14	function	function	NN
cord-347298-7kqrl3rv	1070	15	,	,	,
cord-347298-7kqrl3rv	1070	16	but	but	CC
cord-347298-7kqrl3rv	1070	17	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	1070	18	immune	immune	JJ
cord-347298-7kqrl3rv	1070	19	cell	cell	NN
cord-347298-7kqrl3rv	1070	20	numbers	number	NNS
cord-347298-7kqrl3rv	1070	21	and	and	CC
cord-347298-7kqrl3rv	1070	22	activity	activity	NN
cord-347298-7kqrl3rv	1070	23	may	may	MD
cord-347298-7kqrl3rv	1070	24	become	become	VB
cord-347298-7kqrl3rv	1070	25	permanently	permanently	RB
cord-347298-7kqrl3rv	1070	26	altered	alter	VBN
cord-347298-7kqrl3rv	1070	27	,	,	,
cord-347298-7kqrl3rv	1070	28	with	with	IN
cord-347298-7kqrl3rv	1070	29	possible	possible	JJ
cord-347298-7kqrl3rv	1070	30	implications	implication	NNS
cord-347298-7kqrl3rv	1070	31	for	for	IN
cord-347298-7kqrl3rv	1070	32	future	future	JJ
cord-347298-7kqrl3rv	1070	33	toxic	toxic	JJ
cord-347298-7kqrl3rv	1070	34	or	or	CC
cord-347298-7kqrl3rv	1070	35	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	1070	36	episodes	episode	NNS
cord-347298-7kqrl3rv	1070	37	.	.	.
cord-347298-7kqrl3rv	1071	1	In	in	IN
cord-347298-7kqrl3rv	1071	2	certain	certain	JJ
cord-347298-7kqrl3rv	1071	3	circumstances	circumstance	NNS
cord-347298-7kqrl3rv	1071	4	,	,	,
cord-347298-7kqrl3rv	1071	5	which	which	WDT
cord-347298-7kqrl3rv	1071	6	may	may	MD
cord-347298-7kqrl3rv	1071	7	depend	depend	VB
cord-347298-7kqrl3rv	1071	8	upon	upon	IN
cord-347298-7kqrl3rv	1071	9	the	the	DT
cord-347298-7kqrl3rv	1071	10	severity	severity	NN
cord-347298-7kqrl3rv	1071	11	of	of	IN
cord-347298-7kqrl3rv	1071	12	the	the	DT
cord-347298-7kqrl3rv	1071	13	initial	initial	JJ
cord-347298-7kqrl3rv	1071	14	damage	damage	NN
cord-347298-7kqrl3rv	1071	15	caused	cause	VBN
cord-347298-7kqrl3rv	1071	16	or	or	CC
cord-347298-7kqrl3rv	1071	17	the	the	DT
cord-347298-7kqrl3rv	1071	18	genetic	genetic	JJ
cord-347298-7kqrl3rv	1071	19	background	background	NN
cord-347298-7kqrl3rv	1071	20	of	of	IN
cord-347298-7kqrl3rv	1071	21	the	the	DT
cord-347298-7kqrl3rv	1071	22	patient	patient	NN
cord-347298-7kqrl3rv	1071	23	,	,	,
cord-347298-7kqrl3rv	1071	24	the	the	DT
cord-347298-7kqrl3rv	1071	25	antigen	antigen	NN
cord-347298-7kqrl3rv	1071	26	-	-	HYPH
cord-347298-7kqrl3rv	1071	27	presenting	present	VBG
cord-347298-7kqrl3rv	1071	28	activity	activity	NN
cord-347298-7kqrl3rv	1071	29	of	of	IN
cord-347298-7kqrl3rv	1071	30	intratesticular	intratesticular	JJ
cord-347298-7kqrl3rv	1071	31	dendritic	dendritic	JJ
cord-347298-7kqrl3rv	1071	32	cells	cell	NNS
cord-347298-7kqrl3rv	1071	33	or	or	CC
cord-347298-7kqrl3rv	1071	34	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	1071	35	may	may	MD
cord-347298-7kqrl3rv	1071	36	also	also	RB
cord-347298-7kqrl3rv	1071	37	be	be	VB
cord-347298-7kqrl3rv	1071	38	activated	activate	VBN
cord-347298-7kqrl3rv	1071	39	.	.	.
cord-347298-7kqrl3rv	1072	1	This	this	DT
cord-347298-7kqrl3rv	1072	2	may	may	MD
cord-347298-7kqrl3rv	1072	3	lead	lead	VB
cord-347298-7kqrl3rv	1072	4	to	to	IN
cord-347298-7kqrl3rv	1072	5	recruitment	recruitment	NN
cord-347298-7kqrl3rv	1072	6	and	and	CC
cord-347298-7kqrl3rv	1072	7	activation	activation	NN
cord-347298-7kqrl3rv	1072	8	of	of	IN
cord-347298-7kqrl3rv	1072	9	testicular	testicular	JJ
cord-347298-7kqrl3rv	1072	10	antigen	antigen	NN
cord-347298-7kqrl3rv	1072	11	-	-	HYPH
cord-347298-7kqrl3rv	1072	12	specific	specific	JJ
cord-347298-7kqrl3rv	1072	13	T	t	NN
cord-347298-7kqrl3rv	1072	14	cells	cell	NNS
cord-347298-7kqrl3rv	1072	15	,	,	,
cord-347298-7kqrl3rv	1072	16	development	development	NN
cord-347298-7kqrl3rv	1072	17	of	of	IN
cord-347298-7kqrl3rv	1072	18	cytotoxic	cytotoxic	JJ
cord-347298-7kqrl3rv	1072	19	T	t	NN
cord-347298-7kqrl3rv	1072	20	cells	cell	NNS
cord-347298-7kqrl3rv	1072	21	(	(	-LRB-
cord-347298-7kqrl3rv	1072	22	CTL	CTL	NNP
cord-347298-7kqrl3rv	1072	23	)	)	-RRB-
cord-347298-7kqrl3rv	1072	24	,	,	,
cord-347298-7kqrl3rv	1072	25	and	and	CC
cord-347298-7kqrl3rv	1072	26	B	b	NN
cord-347298-7kqrl3rv	1072	27	cell	cell	NN
cord-347298-7kqrl3rv	1072	28	antibody	antibody	NN
cord-347298-7kqrl3rv	1072	29	(	(	-LRB-
cord-347298-7kqrl3rv	1072	30	Ig	Ig	NNP
cord-347298-7kqrl3rv	1072	31	)	)	-RRB-
cord-347298-7kqrl3rv	1072	32	production	production	NN
cord-347298-7kqrl3rv	1072	33	.	.	.
cord-347298-7kqrl3rv	1073	1	This	this	DT
cord-347298-7kqrl3rv	1073	2	subsequent	subsequent	JJ
cord-347298-7kqrl3rv	1073	3	autoimmunity	autoimmunity	NN
cord-347298-7kqrl3rv	1073	4	may	may	MD
cord-347298-7kqrl3rv	1073	5	have	have	VB
cord-347298-7kqrl3rv	1073	6	a	a	DT
cord-347298-7kqrl3rv	1073	7	more	more	RBR
cord-347298-7kqrl3rv	1073	8	permanent	permanent	JJ
cord-347298-7kqrl3rv	1073	9	effect	effect	NN
cord-347298-7kqrl3rv	1073	10	on	on	IN
cord-347298-7kqrl3rv	1073	11	testis	testis	NN
cord-347298-7kqrl3rv	1073	12	or	or	CC
cord-347298-7kqrl3rv	1073	13	sperm	sperm	NN
cord-347298-7kqrl3rv	1073	14	function	function	NN
cord-347298-7kqrl3rv	1073	15	(	(	-LRB-
cord-347298-7kqrl3rv	1073	16	epithelial	epithelial	JJ
cord-347298-7kqrl3rv	1073	17	destruction	destruction	NN
cord-347298-7kqrl3rv	1073	18	or	or	CC
cord-347298-7kqrl3rv	1073	19	sperm	sperm	NN
cord-347298-7kqrl3rv	1073	20	antibody	antibody	NN
cord-347298-7kqrl3rv	1073	21	formation	formation	NN
cord-347298-7kqrl3rv	1073	22	)	)	-RRB-
cord-347298-7kqrl3rv	1073	23	.	.	.
cord-347298-7kqrl3rv	1074	1	spermatogenic	spermatogenic	NNP
cord-347298-7kqrl3rv	1074	2	development	development	NNP
cord-347298-7kqrl3rv	1074	3	,	,	,
cord-347298-7kqrl3rv	1074	4	or	or	CC
cord-347298-7kqrl3rv	1074	5	local	local	JJ
cord-347298-7kqrl3rv	1074	6	immunoregulation	immunoregulation	NN
cord-347298-7kqrl3rv	1074	7	.	.	.
cord-347298-7kqrl3rv	1075	1	The	the	DT
cord-347298-7kqrl3rv	1075	2	danger	danger	NN
cord-347298-7kqrl3rv	1075	3	hypothesis	hypothesis	NN
cord-347298-7kqrl3rv	1075	4	model	model	NN
cord-347298-7kqrl3rv	1075	5	of	of	IN
cord-347298-7kqrl3rv	1075	6	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1075	7	disease	disease	NN
cord-347298-7kqrl3rv	1075	8	may	may	MD
cord-347298-7kqrl3rv	1075	9	be	be	VB
cord-347298-7kqrl3rv	1075	10	particularly	particularly	RB
cord-347298-7kqrl3rv	1075	11	relevant	relevant	JJ
cord-347298-7kqrl3rv	1075	12	in	in	IN
cord-347298-7kqrl3rv	1075	13	this	this	DT
cord-347298-7kqrl3rv	1075	14	instance	instance	NN
cord-347298-7kqrl3rv	1075	15	(	(	-LRB-
cord-347298-7kqrl3rv	1075	16	Matzinger	Matzinger	NNP
cord-347298-7kqrl3rv	1075	17	1994	1994	CD
cord-347298-7kqrl3rv	1075	18	)	)	-RRB-
cord-347298-7kqrl3rv	1075	19	.	.	.
cord-347298-7kqrl3rv	1076	1	At	at	RB
cord-347298-7kqrl3rv	1076	2	least	least	RBS
cord-347298-7kqrl3rv	1076	3	one	one	CD
cord-347298-7kqrl3rv	1076	4	of	of	IN
cord-347298-7kqrl3rv	1076	5	the	the	DT
cord-347298-7kqrl3rv	1076	6	putative	putative	JJ
cord-347298-7kqrl3rv	1076	7	'	'	``
cord-347298-7kqrl3rv	1076	8	danger	danger	NN
cord-347298-7kqrl3rv	1076	9	'	'	''
cord-347298-7kqrl3rv	1076	10	molecules	molecule	NNS
cord-347298-7kqrl3rv	1076	11	(	(	-LRB-
cord-347298-7kqrl3rv	1076	12	i.e.	i.e.	FW
cord-347298-7kqrl3rv	1076	13	,	,	,
cord-347298-7kqrl3rv	1076	14	TNF	TNF	NNP
cord-347298-7kqrl3rv	1076	15	)	)	-RRB-
cord-347298-7kqrl3rv	1076	16	is	be	VBZ
cord-347298-7kqrl3rv	1076	17	endogenously	endogenously	RB
cord-347298-7kqrl3rv	1076	18	produced	produce	VBN
cord-347298-7kqrl3rv	1076	19	in	in	IN
cord-347298-7kqrl3rv	1076	20	the	the	DT
cord-347298-7kqrl3rv	1076	21	testis	testis	NN
cord-347298-7kqrl3rv	1076	22	,	,	,
cord-347298-7kqrl3rv	1076	23	potentially	potentially	RB
cord-347298-7kqrl3rv	1076	24	presenting	present	VBG
cord-347298-7kqrl3rv	1076	25	a	a	DT
cord-347298-7kqrl3rv	1076	26	continuous	continuous	JJ
cord-347298-7kqrl3rv	1076	27	challenge	challenge	NN
cord-347298-7kqrl3rv	1076	28	to	to	IN
cord-347298-7kqrl3rv	1076	29	the	the	DT
cord-347298-7kqrl3rv	1076	30	testicular	testicular	JJ
cord-347298-7kqrl3rv	1076	31	immune	immune	JJ
cord-347298-7kqrl3rv	1076	32	system	system	NN
cord-347298-7kqrl3rv	1076	33	.	.	.
cord-347298-7kqrl3rv	1077	1	3	3	LS
cord-347298-7kqrl3rv	1077	2	.	.	.
cord-347298-7kqrl3rv	1078	1	Drugs	drug	NNS
cord-347298-7kqrl3rv	1078	2	or	or	CC
cord-347298-7kqrl3rv	1078	3	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1078	4	that	that	WDT
cord-347298-7kqrl3rv	1078	5	induce	induce	VBP
cord-347298-7kqrl3rv	1078	6	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1078	7	disease	disease	NN
cord-347298-7kqrl3rv	1078	8	or	or	CC
cord-347298-7kqrl3rv	1078	9	allergy	allergy	NN
cord-347298-7kqrl3rv	1078	10	may	may	MD
cord-347298-7kqrl3rv	1078	11	also	also	RB
cord-347298-7kqrl3rv	1078	12	induce	induce	VB
cord-347298-7kqrl3rv	1078	13	testicular	testicular	JJ
cord-347298-7kqrl3rv	1078	14	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1078	15	disease	disease	NN
cord-347298-7kqrl3rv	1078	16	.	.	.
cord-347298-7kqrl3rv	1079	1	There	there	EX
cord-347298-7kqrl3rv	1079	2	are	be	VBP
cord-347298-7kqrl3rv	1079	3	many	many	JJ
cord-347298-7kqrl3rv	1079	4	drugs	drug	NNS
cord-347298-7kqrl3rv	1079	5	that	that	WDT
cord-347298-7kqrl3rv	1079	6	induce	induce	VBP
cord-347298-7kqrl3rv	1079	7	polysystemic	polysystemic	JJ
cord-347298-7kqrl3rv	1079	8	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1079	9	disease	disease	NN
cord-347298-7kqrl3rv	1079	10	and	and	CC
cord-347298-7kqrl3rv	1079	11	this	this	DT
cord-347298-7kqrl3rv	1079	12	may	may	MD
cord-347298-7kqrl3rv	1079	13	also	also	RB
cord-347298-7kqrl3rv	1079	14	include	include	VB
cord-347298-7kqrl3rv	1079	15	reactions	reaction	NNS
cord-347298-7kqrl3rv	1079	16	against	against	IN
cord-347298-7kqrl3rv	1079	17	the	the	DT
cord-347298-7kqrl3rv	1079	18	germ	germ	NN
cord-347298-7kqrl3rv	1079	19	cells	cell	NNS
cord-347298-7kqrl3rv	1079	20	.	.	.
cord-347298-7kqrl3rv	1080	1	An	an	DT
cord-347298-7kqrl3rv	1080	2	example	example	NN
cord-347298-7kqrl3rv	1080	3	here	here	RB
cord-347298-7kqrl3rv	1080	4	is	be	VBZ
cord-347298-7kqrl3rv	1080	5	polyarteritis	polyarteritis	NNP
cord-347298-7kqrl3rv	1080	6	nodosa	nodosa	NNP
cord-347298-7kqrl3rv	1080	7	,	,	,
cord-347298-7kqrl3rv	1080	8	a	a	DT
cord-347298-7kqrl3rv	1080	9	necrotizing	necrotize	VBG
cord-347298-7kqrl3rv	1080	10	vasculitis	vasculitis	NN
cord-347298-7kqrl3rv	1080	11	of	of	IN
cord-347298-7kqrl3rv	1080	12	small	small	JJ
cord-347298-7kqrl3rv	1080	13	arteries	artery	NNS
cord-347298-7kqrl3rv	1080	14	,	,	,
cord-347298-7kqrl3rv	1080	15	which	which	WDT
cord-347298-7kqrl3rv	1080	16	frequently	frequently	RB
cord-347298-7kqrl3rv	1080	17	involves	involve	VBZ
cord-347298-7kqrl3rv	1080	18	the	the	DT
cord-347298-7kqrl3rv	1080	19	testis	testis	NN
cord-347298-7kqrl3rv	1080	20	(	(	-LRB-
cord-347298-7kqrl3rv	1080	21	Fauci	Fauci	NNP
cord-347298-7kqrl3rv	1080	22	et	et	NNP
cord-347298-7kqrl3rv	1080	23	al	al	NNP
cord-347298-7kqrl3rv	1080	24	.	.	.
cord-347298-7kqrl3rv	1080	25	1978	1978	CD
cord-347298-7kqrl3rv	1080	26	)	)	-RRB-
cord-347298-7kqrl3rv	1080	27	.	.	.
cord-347298-7kqrl3rv	1081	1	Sulfonamides	sulfonamide	NNS
cord-347298-7kqrl3rv	1081	2	,	,	,
cord-347298-7kqrl3rv	1081	3	penicillin	penicillin	NN
cord-347298-7kqrl3rv	1081	4	,	,	,
cord-347298-7kqrl3rv	1081	5	phenytoin	phenytoin	NN
cord-347298-7kqrl3rv	1081	6	,	,	,
cord-347298-7kqrl3rv	1081	7	arsenicals	arsenical	NNS
cord-347298-7kqrl3rv	1081	8	,	,	,
cord-347298-7kqrl3rv	1081	9	thiouracil	thiouracil	NNP
cord-347298-7kqrl3rv	1081	10	,	,	,
cord-347298-7kqrl3rv	1081	11	iodides	iodide	NNS
cord-347298-7kqrl3rv	1081	12	,	,	,
cord-347298-7kqrl3rv	1081	13	and	and	CC
cord-347298-7kqrl3rv	1081	14	thiazides	thiazide	NNS
cord-347298-7kqrl3rv	1081	15	are	be	VBP
cord-347298-7kqrl3rv	1081	16	frequently	frequently	RB
cord-347298-7kqrl3rv	1081	17	suspected	suspect	VBN
cord-347298-7kqrl3rv	1081	18	as	as	IN
cord-347298-7kqrl3rv	1081	19	causes	cause	NNS
cord-347298-7kqrl3rv	1081	20	of	of	IN
cord-347298-7kqrl3rv	1081	21	this	this	DT
cord-347298-7kqrl3rv	1081	22	condition	condition	NN
cord-347298-7kqrl3rv	1081	23	(	(	-LRB-
cord-347298-7kqrl3rv	1081	24	Nusinow	Nusinow	NNP
cord-347298-7kqrl3rv	1081	25	et	et	NNP
cord-347298-7kqrl3rv	1081	26	al	al	NNP
cord-347298-7kqrl3rv	1081	27	.	.	.
cord-347298-7kqrl3rv	1081	28	1985	1985	CD
cord-347298-7kqrl3rv	1081	29	)	)	-RRB-
cord-347298-7kqrl3rv	1081	30	.	.	.
cord-347298-7kqrl3rv	1082	1	Likewise	likewise	RB
cord-347298-7kqrl3rv	1082	2	,	,	,
cord-347298-7kqrl3rv	1082	3	mutagens	mutagen	NNS
cord-347298-7kqrl3rv	1082	4	and	and	CC
cord-347298-7kqrl3rv	1082	5	other	other	JJ
cord-347298-7kqrl3rv	1082	6	toxins	toxin	NNS
cord-347298-7kqrl3rv	1082	7	that	that	WDT
cord-347298-7kqrl3rv	1082	8	may	may	MD
cord-347298-7kqrl3rv	1082	9	alter	alter	VB
cord-347298-7kqrl3rv	1082	10	T	T	NNP
cord-347298-7kqrl3rv	1082	11	and	and	CC
cord-347298-7kqrl3rv	1082	12	B	b	NN
cord-347298-7kqrl3rv	1082	13	cell	cell	NN
cord-347298-7kqrl3rv	1082	14	receptor	receptor	NN
cord-347298-7kqrl3rv	1082	15	repertoires	repertoire	NNS
cord-347298-7kqrl3rv	1082	16	to	to	TO
cord-347298-7kqrl3rv	1082	17	create	create	VB
cord-347298-7kqrl3rv	1082	18	self	self	NN
cord-347298-7kqrl3rv	1082	19	-	-	HYPH
cord-347298-7kqrl3rv	1082	20	reactive	reactive	JJ
cord-347298-7kqrl3rv	1082	21	lymphocytes	lymphocyte	NNS
cord-347298-7kqrl3rv	1082	22	could	could	MD
cord-347298-7kqrl3rv	1082	23	also	also	RB
cord-347298-7kqrl3rv	1082	24	contribute	contribute	VB
cord-347298-7kqrl3rv	1082	25	to	to	IN
cord-347298-7kqrl3rv	1082	26	the	the	DT
cord-347298-7kqrl3rv	1082	27	onset	onset	NN
cord-347298-7kqrl3rv	1082	28	of	of	IN
cord-347298-7kqrl3rv	1082	29	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1082	30	disease	disease	NN
cord-347298-7kqrl3rv	1082	31	in	in	IN
cord-347298-7kqrl3rv	1082	32	the	the	DT
cord-347298-7kqrl3rv	1082	33	male	male	JJ
cord-347298-7kqrl3rv	1082	34	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1082	35	tract	tract	NN
cord-347298-7kqrl3rv	1082	36	.	.	.
cord-347298-7kqrl3rv	1083	1	4	4	LS
cord-347298-7kqrl3rv	1083	2	.	.	.
cord-347298-7kqrl3rv	1084	1	Drugs	drug	NNS
cord-347298-7kqrl3rv	1084	2	or	or	CC
cord-347298-7kqrl3rv	1084	3	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1084	4	that	that	WDT
cord-347298-7kqrl3rv	1084	5	affect	affect	VBP
cord-347298-7kqrl3rv	1084	6	testicular	testicular	JJ
cord-347298-7kqrl3rv	1084	7	cell	cell	NN
cord-347298-7kqrl3rv	1084	8	development	development	NN
cord-347298-7kqrl3rv	1084	9	or	or	CC
cord-347298-7kqrl3rv	1084	10	viability	viability	NN
cord-347298-7kqrl3rv	1084	11	may	may	MD
cord-347298-7kqrl3rv	1084	12	also	also	RB
cord-347298-7kqrl3rv	1084	13	induce	induce	VB
cord-347298-7kqrl3rv	1084	14	immune	immune	JJ
cord-347298-7kqrl3rv	1084	15	responses	response	NNS
cord-347298-7kqrl3rv	1084	16	.	.	.
cord-347298-7kqrl3rv	1085	1	There	there	EX
cord-347298-7kqrl3rv	1085	2	are	be	VBP
cord-347298-7kqrl3rv	1085	3	drugs	drug	NNS
cord-347298-7kqrl3rv	1085	4	or	or	CC
cord-347298-7kqrl3rv	1085	5	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1085	6	that	that	WDT
cord-347298-7kqrl3rv	1085	7	affect	affect	VBP
cord-347298-7kqrl3rv	1085	8	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	1085	9	-	-	HYPH
cord-347298-7kqrl3rv	1085	10	Sertoli	Sertoli	NNP
cord-347298-7kqrl3rv	1085	11	and	and	CC
cord-347298-7kqrl3rv	1085	12	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	1085	13	-	-	HYPH
cord-347298-7kqrl3rv	1085	14	germ	germ	NN
cord-347298-7kqrl3rv	1085	15	cell	cell	NN
cord-347298-7kqrl3rv	1085	16	junction	junction	NN
cord-347298-7kqrl3rv	1085	17	stability	stability	NN
cord-347298-7kqrl3rv	1085	18	,	,	,
cord-347298-7kqrl3rv	1085	19	as	as	RB
cord-347298-7kqrl3rv	1085	20	well	well	RB
cord-347298-7kqrl3rv	1085	21	as	as	IN
cord-347298-7kqrl3rv	1085	22	agents	agent	NNS
cord-347298-7kqrl3rv	1085	23	that	that	WDT
cord-347298-7kqrl3rv	1085	24	damage	damage	VBP
cord-347298-7kqrl3rv	1085	25	the	the	DT
cord-347298-7kqrl3rv	1085	26	Sertoli	sertoli	JJ
cord-347298-7kqrl3rv	1085	27	cell	cell	NN
cord-347298-7kqrl3rv	1085	28	or	or	CC
cord-347298-7kqrl3rv	1085	29	germ	germ	NN
cord-347298-7kqrl3rv	1085	30	cells	cell	NNS
cord-347298-7kqrl3rv	1085	31	directly	directly	RB
cord-347298-7kqrl3rv	1085	32	,	,	,
cord-347298-7kqrl3rv	1085	33	resulting	result	VBG
cord-347298-7kqrl3rv	1085	34	in	in	IN
cord-347298-7kqrl3rv	1085	35	massive	massive	JJ
cord-347298-7kqrl3rv	1085	36	germ	germ	NN
cord-347298-7kqrl3rv	1085	37	cell	cell	NN
cord-347298-7kqrl3rv	1085	38	death	death	NN
cord-347298-7kqrl3rv	1085	39	,	,	,
cord-347298-7kqrl3rv	1085	40	which	which	WDT
cord-347298-7kqrl3rv	1085	41	may	may	MD
cord-347298-7kqrl3rv	1085	42	overwhelm	overwhelm	VB
cord-347298-7kqrl3rv	1085	43	the	the	DT
cord-347298-7kqrl3rv	1085	44	normal	normal	JJ
cord-347298-7kqrl3rv	1085	45	immunoregulatory	immunoregulatory	JJ
cord-347298-7kqrl3rv	1085	46	capacity	capacity	NN
cord-347298-7kqrl3rv	1085	47	of	of	IN
cord-347298-7kqrl3rv	1085	48	the	the	DT
cord-347298-7kqrl3rv	1085	49	testis	testis	NN
cord-347298-7kqrl3rv	1085	50	.	.	.
cord-347298-7kqrl3rv	1086	1	Examples	example	NNS
cord-347298-7kqrl3rv	1086	2	of	of	IN
cord-347298-7kqrl3rv	1086	3	this	this	DT
cord-347298-7kqrl3rv	1086	4	interaction	interaction	NN
cord-347298-7kqrl3rv	1086	5	are	be	VBP
cord-347298-7kqrl3rv	1086	6	seen	see	VBN
cord-347298-7kqrl3rv	1086	7	after	after	IN
cord-347298-7kqrl3rv	1086	8	testicular	testicular	JJ
cord-347298-7kqrl3rv	1086	9	heating	heating	NN
cord-347298-7kqrl3rv	1086	10	,	,	,
cord-347298-7kqrl3rv	1086	11	serotonin	serotonin	NNP
cord-347298-7kqrl3rv	1086	12	administration	administration	NN
cord-347298-7kqrl3rv	1086	13	,	,	,
cord-347298-7kqrl3rv	1086	14	or	or	CC
cord-347298-7kqrl3rv	1086	15	treatment	treatment	NN
cord-347298-7kqrl3rv	1086	16	with	with	IN
cord-347298-7kqrl3rv	1086	17	ethane	ethane	NN
cord-347298-7kqrl3rv	1086	18	dimethane	dimethane	NNP
cord-347298-7kqrl3rv	1086	19	sulfonate	sulfonate	NNP
cord-347298-7kqrl3rv	1086	20	(	(	-LRB-
cord-347298-7kqrl3rv	1086	21	EDS	EDS	NNP
cord-347298-7kqrl3rv	1086	22	)	)	-RRB-
cord-347298-7kqrl3rv	1086	23	or	or	CC
cord-347298-7kqrl3rv	1086	24	other	other	JJ
cord-347298-7kqrl3rv	1086	25	testicular	testicular	JJ
cord-347298-7kqrl3rv	1086	26	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1086	27	,	,	,
cord-347298-7kqrl3rv	1086	28	which	which	WDT
cord-347298-7kqrl3rv	1086	29	are	be	VBP
cord-347298-7kqrl3rv	1086	30	frequently	frequently	RB
cord-347298-7kqrl3rv	1086	31	followed	follow	VBN
cord-347298-7kqrl3rv	1086	32	by	by	IN
cord-347298-7kqrl3rv	1086	33	transient	transient	JJ
cord-347298-7kqrl3rv	1086	34	immune	immune	NN
cord-347298-7kqrl3rv	1086	35	and/or	and/or	CC
cord-347298-7kqrl3rv	1086	36	inflammatory	inflammatory	JJ
cord-347298-7kqrl3rv	1086	37	events	event	NNS
cord-347298-7kqrl3rv	1086	38	(	(	-LRB-
cord-347298-7kqrl3rv	1086	39	Creasy	Creasy	NNP
cord-347298-7kqrl3rv	1086	40	et	et	FW
cord-347298-7kqrl3rv	1086	41	al	al	NNP
cord-347298-7kqrl3rv	1086	42	.	.	.
cord-347298-7kqrl3rv	1086	43	1983	1983	CD
cord-347298-7kqrl3rv	1086	44	;	;	:
cord-347298-7kqrl3rv	1086	45	Hedger	Hedger	NNP
cord-347298-7kqrl3rv	1086	46	et	et	NNP
cord-347298-7kqrl3rv	1086	47	al	al	NNP
cord-347298-7kqrl3rv	1086	48	.	.	NNP
cord-347298-7kqrl3rv	1086	49	1995	1995	CD
cord-347298-7kqrl3rv	1086	50	;	;	:
cord-347298-7kqrl3rv	1086	51	Padmanabhan	Padmanabhan	NNP
cord-347298-7kqrl3rv	1086	52	and	and	CC
cord-347298-7kqrl3rv	1086	53	Singh	Singh	NNP
cord-347298-7kqrl3rv	1086	54	1981	1981	CD
cord-347298-7kqrl3rv	1086	55	;	;	:
cord-347298-7kqrl3rv	1086	56	Wang	Wang	NNP
cord-347298-7kqrl3rv	1086	57	et	et	NNP
cord-347298-7kqrl3rv	1086	58	al	al	NNP
cord-347298-7kqrl3rv	1086	59	.	.	.
cord-347298-7kqrl3rv	1086	60	1994	1994	CD
cord-347298-7kqrl3rv	1086	61	)	)	-RRB-
cord-347298-7kqrl3rv	1086	62	.	.	.
cord-347298-7kqrl3rv	1087	1	Even	even	RB
cord-347298-7kqrl3rv	1087	2	if	if	IN
cord-347298-7kqrl3rv	1087	3	the	the	DT
cord-347298-7kqrl3rv	1087	4	epithelium	epithelium	NN
cord-347298-7kqrl3rv	1087	5	recovers	recover	VBZ
cord-347298-7kqrl3rv	1087	6	fully	fully	RB
cord-347298-7kqrl3rv	1087	7	,	,	,
cord-347298-7kqrl3rv	1087	8	there	there	EX
cord-347298-7kqrl3rv	1087	9	is	be	VBZ
cord-347298-7kqrl3rv	1087	10	the	the	DT
cord-347298-7kqrl3rv	1087	11	potential	potential	NN
cord-347298-7kqrl3rv	1087	12	for	for	IN
cord-347298-7kqrl3rv	1087	13	sperm	sperm	NN
cord-347298-7kqrl3rv	1087	14	antibody	antibody	NN
cord-347298-7kqrl3rv	1087	15	development	development	NN
cord-347298-7kqrl3rv	1087	16	,	,	,
cord-347298-7kqrl3rv	1087	17	leading	lead	VBG
cord-347298-7kqrl3rv	1087	18	to	to	IN
cord-347298-7kqrl3rv	1087	19	reduced	reduce	VBN
cord-347298-7kqrl3rv	1087	20	fertility	fertility	NN
cord-347298-7kqrl3rv	1087	21	.	.	.
cord-347298-7kqrl3rv	1088	1	Increased	increase	VBN
cord-347298-7kqrl3rv	1088	2	exposure	exposure	NN
cord-347298-7kqrl3rv	1088	3	to	to	IN
cord-347298-7kqrl3rv	1088	4	estrogenic	estrogenic	JJ
cord-347298-7kqrl3rv	1088	5	compounds	compound	NNS
cord-347298-7kqrl3rv	1088	6	is	be	VBZ
cord-347298-7kqrl3rv	1088	7	associated	associate	VBN
cord-347298-7kqrl3rv	1088	8	with	with	IN
cord-347298-7kqrl3rv	1088	9	activation	activation	NN
cord-347298-7kqrl3rv	1088	10	of	of	IN
cord-347298-7kqrl3rv	1088	11	immune	immune	JJ
cord-347298-7kqrl3rv	1088	12	cells	cell	NNS
cord-347298-7kqrl3rv	1088	13	in	in	IN
cord-347298-7kqrl3rv	1088	14	the	the	DT
cord-347298-7kqrl3rv	1088	15	testis	testis	NN
cord-347298-7kqrl3rv	1088	16	,	,	,
cord-347298-7kqrl3rv	1088	17	most	most	RBS
cord-347298-7kqrl3rv	1088	18	notably	notably	RB
cord-347298-7kqrl3rv	1088	19	the	the	DT
cord-347298-7kqrl3rv	1088	20	macrophages	macrophage	NNS
cord-347298-7kqrl3rv	1088	21	,	,	,
cord-347298-7kqrl3rv	1088	22	providing	provide	VBG
cord-347298-7kqrl3rv	1088	23	evidence	evidence	NN
cord-347298-7kqrl3rv	1088	24	for	for	IN
cord-347298-7kqrl3rv	1088	25	a	a	DT
cord-347298-7kqrl3rv	1088	26	mechanism	mechanism	NN
cord-347298-7kqrl3rv	1088	27	whereby	whereby	WRB
cord-347298-7kqrl3rv	1088	28	environmental	environmental	JJ
cord-347298-7kqrl3rv	1088	29	estrogens	estrogen	NNS
cord-347298-7kqrl3rv	1088	30	may	may	MD
cord-347298-7kqrl3rv	1088	31	affect	affect	VB
cord-347298-7kqrl3rv	1088	32	male	male	JJ
cord-347298-7kqrl3rv	1088	33	fertility	fertility	NN
cord-347298-7kqrl3rv	1088	34	indirectly	indirectly	RB
cord-347298-7kqrl3rv	1088	35	via	via	IN
cord-347298-7kqrl3rv	1088	36	effects	effect	NNS
cord-347298-7kqrl3rv	1088	37	on	on	IN
cord-347298-7kqrl3rv	1088	38	local	local	JJ
cord-347298-7kqrl3rv	1088	39	immunity	immunity	NN
cord-347298-7kqrl3rv	1088	40	(	(	-LRB-
cord-347298-7kqrl3rv	1088	41	Li	Li	NNP
cord-347298-7kqrl3rv	1088	42	et	et	NNP
cord-347298-7kqrl3rv	1088	43	al	al	NNP
cord-347298-7kqrl3rv	1088	44	.	.	NNP
cord-347298-7kqrl3rv	1088	45	2006b	2006b	CD
cord-347298-7kqrl3rv	1088	46	)	)	-RRB-
cord-347298-7kqrl3rv	1088	47	.	.	.
cord-347298-7kqrl3rv	1089	1	5	5	LS
cord-347298-7kqrl3rv	1089	2	.	.	.
cord-347298-7kqrl3rv	1090	1	Testicular	testicular	JJ
cord-347298-7kqrl3rv	1090	2	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1090	3	that	that	WDT
cord-347298-7kqrl3rv	1090	4	alter	alter	VBP
cord-347298-7kqrl3rv	1090	5	steroidogenic	steroidogenic	JJ
cord-347298-7kqrl3rv	1090	6	cell	cell	NN
cord-347298-7kqrl3rv	1090	7	function	function	NN
cord-347298-7kqrl3rv	1090	8	will	will	MD
cord-347298-7kqrl3rv	1090	9	have	have	VB
cord-347298-7kqrl3rv	1090	10	a	a	DT
cord-347298-7kqrl3rv	1090	11	direct	direct	JJ
cord-347298-7kqrl3rv	1090	12	effect	effect	NN
cord-347298-7kqrl3rv	1090	13	on	on	IN
cord-347298-7kqrl3rv	1090	14	the	the	DT
cord-347298-7kqrl3rv	1090	15	immune	immune	JJ
cord-347298-7kqrl3rv	1090	16	system	system	NN
cord-347298-7kqrl3rv	1090	17	.	.	.
cord-347298-7kqrl3rv	1091	1	Toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1091	2	that	that	IN
cord-347298-7kqrl3rv	1091	3	damage	damage	VBP
cord-347298-7kqrl3rv	1091	4	Leydig	leydig	NN
cord-347298-7kqrl3rv	1091	5	cells	cell	NNS
cord-347298-7kqrl3rv	1091	6	and	and	CC
cord-347298-7kqrl3rv	1091	7	reduce	reduce	VB
cord-347298-7kqrl3rv	1091	8	steroid	steroid	NN
cord-347298-7kqrl3rv	1091	9	production	production	NN
cord-347298-7kqrl3rv	1091	10	possibly	possibly	RB
cord-347298-7kqrl3rv	1091	11	could	could	MD
cord-347298-7kqrl3rv	1091	12	alter	alter	VB
cord-347298-7kqrl3rv	1091	13	thymus	thymus	NN
cord-347298-7kqrl3rv	1091	14	function	function	NN
cord-347298-7kqrl3rv	1091	15	,	,	,
cord-347298-7kqrl3rv	1091	16	leading	lead	VBG
cord-347298-7kqrl3rv	1091	17	to	to	IN
cord-347298-7kqrl3rv	1091	18	an	an	DT
cord-347298-7kqrl3rv	1091	19	enhanced	enhance	VBN
cord-347298-7kqrl3rv	1091	20	susceptibility	susceptibility	NN
cord-347298-7kqrl3rv	1091	21	to	to	IN
cord-347298-7kqrl3rv	1091	22	autoimmune	autoimmune	JJ
cord-347298-7kqrl3rv	1091	23	disease	disease	NN
cord-347298-7kqrl3rv	1091	24	.	.	.
cord-347298-7kqrl3rv	1092	1	Balanced	balance	VBN
cord-347298-7kqrl3rv	1092	2	against	against	IN
cord-347298-7kqrl3rv	1092	3	this	this	DT
cord-347298-7kqrl3rv	1092	4	is	be	VBZ
cord-347298-7kqrl3rv	1092	5	the	the	DT
cord-347298-7kqrl3rv	1092	6	likelihood	likelihood	NN
cord-347298-7kqrl3rv	1092	7	that	that	IN
cord-347298-7kqrl3rv	1092	8	other	other	JJ
cord-347298-7kqrl3rv	1092	9	androgen	androgen	NN
cord-347298-7kqrl3rv	1092	10	-	-	HYPH
cord-347298-7kqrl3rv	1092	11	deficiency	deficiency	NN
cord-347298-7kqrl3rv	1092	12	symptoms	symptom	NNS
cord-347298-7kqrl3rv	1092	13	are	be	VBP
cord-347298-7kqrl3rv	1092	14	far	far	RB
cord-347298-7kqrl3rv	1092	15	more	more	RBR
cord-347298-7kqrl3rv	1092	16	likely	likely	JJ
cord-347298-7kqrl3rv	1092	17	to	to	TO
cord-347298-7kqrl3rv	1092	18	be	be	VB
cord-347298-7kqrl3rv	1092	19	manifest	manifest	JJ
cord-347298-7kqrl3rv	1092	20	and	and	CC
cord-347298-7kqrl3rv	1092	21	treated	treat	VBN
cord-347298-7kqrl3rv	1092	22	.	.	.
cord-347298-7kqrl3rv	1093	1	All	all	PDT
cord-347298-7kqrl3rv	1093	2	these	these	DT
cord-347298-7kqrl3rv	1093	3	interactions	interaction	NNS
cord-347298-7kqrl3rv	1093	4	,	,	,
cord-347298-7kqrl3rv	1093	5	however	however	RB
cord-347298-7kqrl3rv	1093	6	,	,	,
cord-347298-7kqrl3rv	1093	7	illustrate	illustrate	VBP
cord-347298-7kqrl3rv	1093	8	to	to	IN
cord-347298-7kqrl3rv	1093	9	one	one	CD
cord-347298-7kqrl3rv	1093	10	degree	degree	NN
cord-347298-7kqrl3rv	1093	11	or	or	CC
cord-347298-7kqrl3rv	1093	12	another	another	DT
cord-347298-7kqrl3rv	1093	13	the	the	DT
cord-347298-7kqrl3rv	1093	14	difficulty	difficulty	NN
cord-347298-7kqrl3rv	1093	15	of	of	IN
cord-347298-7kqrl3rv	1093	16	separating	separate	VBG
cord-347298-7kqrl3rv	1093	17	direct	direct	JJ
cord-347298-7kqrl3rv	1093	18	effects	effect	NNS
cord-347298-7kqrl3rv	1093	19	of	of	IN
cord-347298-7kqrl3rv	1093	20	toxic	toxic	JJ
cord-347298-7kqrl3rv	1093	21	agents	agent	NNS
cord-347298-7kqrl3rv	1093	22	on	on	IN
cord-347298-7kqrl3rv	1093	23	the	the	DT
cord-347298-7kqrl3rv	1093	24	immune	immune	JJ
cord-347298-7kqrl3rv	1093	25	cells	cell	NNS
cord-347298-7kqrl3rv	1093	26	and	and	CC
cord-347298-7kqrl3rv	1093	27	on	on	IN
cord-347298-7kqrl3rv	1093	28	the	the	DT
cord-347298-7kqrl3rv	1093	29	testis	testis	NN
cord-347298-7kqrl3rv	1093	30	.	.	.
cord-347298-7kqrl3rv	1094	1	There	there	EX
cord-347298-7kqrl3rv	1094	2	is	be	VBZ
cord-347298-7kqrl3rv	1094	3	a	a	DT
cord-347298-7kqrl3rv	1094	4	dynamic	dynamic	JJ
cord-347298-7kqrl3rv	1094	5	relationship	relationship	NN
cord-347298-7kqrl3rv	1094	6	between	between	IN
cord-347298-7kqrl3rv	1094	7	the	the	DT
cord-347298-7kqrl3rv	1094	8	male	male	JJ
cord-347298-7kqrl3rv	1094	9	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1094	10	tract	tract	NN
cord-347298-7kqrl3rv	1094	11	and	and	CC
cord-347298-7kqrl3rv	1094	12	the	the	DT
cord-347298-7kqrl3rv	1094	13	immune	immune	JJ
cord-347298-7kqrl3rv	1094	14	system	system	NN
cord-347298-7kqrl3rv	1094	15	that	that	WDT
cord-347298-7kqrl3rv	1094	16	should	should	MD
cord-347298-7kqrl3rv	1094	17	be	be	VB
cord-347298-7kqrl3rv	1094	18	considered	consider	VBN
cord-347298-7kqrl3rv	1094	19	when	when	WRB
cord-347298-7kqrl3rv	1094	20	assessing	assess	VBG
cord-347298-7kqrl3rv	1094	21	the	the	DT
cord-347298-7kqrl3rv	1094	22	effects	effect	NNS
cord-347298-7kqrl3rv	1094	23	of	of	IN
cord-347298-7kqrl3rv	1094	24	various	various	JJ
cord-347298-7kqrl3rv	1094	25	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1094	26	on	on	IN
cord-347298-7kqrl3rv	1094	27	male	male	JJ
cord-347298-7kqrl3rv	1094	28	fertility	fertility	NN
cord-347298-7kqrl3rv	1094	29	and	and	CC
cord-347298-7kqrl3rv	1094	30	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1094	31	development	development	NN
cord-347298-7kqrl3rv	1094	32	.	.	.
cord-347298-7kqrl3rv	1095	1	The	the	DT
cord-347298-7kqrl3rv	1095	2	effects	effect	NNS
cord-347298-7kqrl3rv	1095	3	of	of	IN
cord-347298-7kqrl3rv	1095	4	toxicants	toxicant	NNS
cord-347298-7kqrl3rv	1095	5	on	on	IN
cord-347298-7kqrl3rv	1095	6	male	male	JJ
cord-347298-7kqrl3rv	1095	7	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1095	8	functions	function	NNS
cord-347298-7kqrl3rv	1095	9	,	,	,
cord-347298-7kqrl3rv	1095	10	most	most	RBS
cord-347298-7kqrl3rv	1095	11	notably	notably	RB
cord-347298-7kqrl3rv	1095	12	the	the	DT
cord-347298-7kqrl3rv	1095	13	production	production	NN
cord-347298-7kqrl3rv	1095	14	of	of	IN
cord-347298-7kqrl3rv	1095	15	androgenic	androgenic	JJ
cord-347298-7kqrl3rv	1095	16	steroids	steroid	NNS
cord-347298-7kqrl3rv	1095	17	,	,	,
cord-347298-7kqrl3rv	1095	18	will	will	MD
cord-347298-7kqrl3rv	1095	19	in	in	IN
cord-347298-7kqrl3rv	1095	20	turn	turn	NN
cord-347298-7kqrl3rv	1095	21	impinge	impinge	VB
cord-347298-7kqrl3rv	1095	22	upon	upon	IN
cord-347298-7kqrl3rv	1095	23	the	the	DT
cord-347298-7kqrl3rv	1095	24	functions	function	NNS
cord-347298-7kqrl3rv	1095	25	of	of	IN
cord-347298-7kqrl3rv	1095	26	the	the	DT
cord-347298-7kqrl3rv	1095	27	immune	immune	JJ
cord-347298-7kqrl3rv	1095	28	system	system	NN
cord-347298-7kqrl3rv	1095	29	.	.	.
cord-347298-7kqrl3rv	1096	1	Many	many	JJ
cord-347298-7kqrl3rv	1096	2	mechanisms	mechanism	NNS
cord-347298-7kqrl3rv	1096	3	underlying	underlie	VBG
cord-347298-7kqrl3rv	1096	4	these	these	DT
cord-347298-7kqrl3rv	1096	5	interactions	interaction	NNS
cord-347298-7kqrl3rv	1096	6	have	have	VBP
cord-347298-7kqrl3rv	1096	7	begun	begin	VBN
cord-347298-7kqrl3rv	1096	8	to	to	TO
cord-347298-7kqrl3rv	1096	9	emerge	emerge	VB
cord-347298-7kqrl3rv	1096	10	in	in	IN
cord-347298-7kqrl3rv	1096	11	recent	recent	JJ
cord-347298-7kqrl3rv	1096	12	years	year	NNS
cord-347298-7kqrl3rv	1096	13	,	,	,
cord-347298-7kqrl3rv	1096	14	but	but	CC
cord-347298-7kqrl3rv	1096	15	a	a	DT
cord-347298-7kqrl3rv	1096	16	complete	complete	JJ
cord-347298-7kqrl3rv	1096	17	picture	picture	NN
cord-347298-7kqrl3rv	1096	18	remains	remain	VBZ
cord-347298-7kqrl3rv	1096	19	hidden	hide	VBN
cord-347298-7kqrl3rv	1096	20	.	.	.
cord-347298-7kqrl3rv	1097	1	Further	further	JJ
cord-347298-7kqrl3rv	1097	2	studies	study	NNS
cord-347298-7kqrl3rv	1097	3	will	will	MD
cord-347298-7kqrl3rv	1097	4	no	no	RB
cord-347298-7kqrl3rv	1097	5	doubt	doubt	RB
cord-347298-7kqrl3rv	1097	6	lead	lead	VB
cord-347298-7kqrl3rv	1097	7	to	to	IN
cord-347298-7kqrl3rv	1097	8	important	important	JJ
cord-347298-7kqrl3rv	1097	9	new	new	JJ
cord-347298-7kqrl3rv	1097	10	concepts	concept	NNS
cord-347298-7kqrl3rv	1097	11	concerning	concern	VBG
cord-347298-7kqrl3rv	1097	12	this	this	DT
cord-347298-7kqrl3rv	1097	13	relationship	relationship	NN
cord-347298-7kqrl3rv	1097	14	and	and	CC
cord-347298-7kqrl3rv	1097	15	its	-PRON-	PRP$
cord-347298-7kqrl3rv	1097	16	implications	implication	NNS
cord-347298-7kqrl3rv	1097	17	for	for	IN
cord-347298-7kqrl3rv	1097	18	reproductive	reproductive	JJ
cord-347298-7kqrl3rv	1097	19	toxicology	toxicology	NN
cord-347298-7kqrl3rv	1097	20	.	.	.
cord-347298-7kqrl3rv	1098	1	Proc	proc	VB
cord-347298-7kqrl3rv	1098	2	.	.	.
cord-347298-7kqrl3rv	1099	1	Natl	Natl	NNP
cord-347298-7kqrl3rv	1099	2	.	.	.
cord-347298-7kqrl3rv	1100	1	Acad	Acad	NNP
cord-347298-7kqrl3rv	1100	2	.	.	.
cord-347298-7kqrl3rv	1101	1	Sci	Sci	NNP
cord-347298-7kqrl3rv	1101	2	Cellular	Cellular	NNP
cord-347298-7kqrl3rv	1101	3	Transplantation	Transplantation	NNP
cord-347298-7kqrl3rv	1101	4	from	from	IN
cord-347298-7kqrl3rv	1101	5	Laboratory	Laboratory	NNP
cord-347298-7kqrl3rv	1101	6	to	to	IN
cord-347298-7kqrl3rv	1101	7	Clinic	Clinic	NNP
cord-347298-7kqrl3rv	1101	8	;	;	:
cord-347298-7kqrl3rv	1101	9	Halberstadt	Halberstadt	NNP
cord-347298-7kqrl3rv	1101	10	In	in	IN
cord-347298-7kqrl3rv	1101	11	Knobil	Knobil	NNP
cord-347298-7kqrl3rv	1101	12	and	and	CC
cord-347298-7kqrl3rv	1101	13	Neill	Neill	NNP
cord-347298-7kqrl3rv	1101	14	's	's	POS
cord-347298-7kqrl3rv	1101	15	Physiology	Physiology	NNP
cord-347298-7kqrl3rv	1101	16	of	of	IN
cord-347298-7kqrl3rv	1101	17	Reproduction	Reproduction	NNP
cord-347298-7kqrl3rv	1101	18	Proc	Proc	NNP
cord-347298-7kqrl3rv	1101	19	.	.	.
cord-347298-7kqrl3rv	1102	1	Natl	Natl	NNP
cord-347298-7kqrl3rv	1102	2	.	.	.
cord-347298-7kqrl3rv	1102	3	Acad	Acad	NNP
cord-347298-7kqrl3rv	1102	4	.	.	.
cord-347298-7kqrl3rv	1103	1	Sci	Sci	NNP
cord-347298-7kqrl3rv	1103	2	Proc	Proc	NNP
cord-347298-7kqrl3rv	1103	3	.	.	.
cord-347298-7kqrl3rv	1104	1	Natl	Natl	NNP
cord-347298-7kqrl3rv	1104	2	.	.	.
cord-347298-7kqrl3rv	1104	3	Acad	Acad	NNP
cord-347298-7kqrl3rv	1104	4	.	.	.
cord-347298-7kqrl3rv	1105	1	Sci	Sci	NNP
cord-347298-7kqrl3rv	1105	2	Tight	Tight	NNP
cord-347298-7kqrl3rv	1105	3	Junctions	Junctions	NNPS
cord-347298-7kqrl3rv	1106	1	Sainio	Sainio	NNP
cord-347298-7kqrl3rv	1107	1	-Pö	-Pö	:
cord-347298-7kqrl3rv	1107	2	llä	llä	JJ
cord-347298-7kqrl3rv	1107	3	nen	nen	NNP
cord-347298-7kqrl3rv	1107	4	,	,	,
cord-347298-7kqrl3rv	1107	5	S.	S.	NNP
cord-347298-7kqrl3rv	1107	6	;	;	:
cord-347298-7kqrl3rv	1107	7	Sö	Sö	NNP
cord-347298-7kqrl3rv	1107	8	der	der	NNP
cord-347298-7kqrl3rv	1107	9	Aderem	Aderem	NNP
cord-347298-7kqrl3rv	1107	10	,	,	,
cord-347298-7kqrl3rv	1107	11	A.	a.	NN
cord-347298-7kqrl3rv	1107	12	Proc	proc	NN
cord-347298-7kqrl3rv	1107	13	.	.	.
cord-347298-7kqrl3rv	1108	1	Natl	Natl	NNP
cord-347298-7kqrl3rv	1108	2	.	.	.
cord-347298-7kqrl3rv	1108	3	Acad	Acad	NNP
cord-347298-7kqrl3rv	1108	4	.	.	.
cord-347298-7kqrl3rv	1109	1	Sci	Sci	NNP
cord-347298-7kqrl3rv	1109	2	Fundamental	Fundamental	NNP
cord-347298-7kqrl3rv	1109	3	Immunology	Immunology	NNP
cord-347298-7kqrl3rv	1110	1	Pö	pö	NN
cord-347298-7kqrl3rv	1111	1	llä	llä	NNP
cord-347298-7kqrl3rv	1111	2	nen	nen	NNP
cord-347298-7kqrl3rv	1111	3	Inflammation	Inflammation	NNP
cord-347298-7kqrl3rv	1111	4	:	:	:
cord-347298-7kqrl3rv	1111	5	Basic	Basic	NNP
cord-347298-7kqrl3rv	1111	6	Principles	Principles	NNPS
cord-347298-7kqrl3rv	1111	7	and	and	CC
cord-347298-7kqrl3rv	1111	8	Clinical	Clinical	NNP
cord-347298-7kqrl3rv	1111	9	Correlates	Correlates	NNPS