id author title date pages extension mime words sentences flesch summary cache txt cord-006435-4o8uu6d5 Kivity, Shaye Evidence for the Use of Intravenous Immunoglobulins—A Review of the Literature 2009-07-10 .txt text/plain 14141 874 36 Although convincing evidence is lacking for the use of IVIg in view of the severity and the refractory nature of several cases of Evans' syndrome, IVIg may be considered among the treatment options generally together with CS with or without immunosuppressive therapy (strength of recommendation IIb). Level of evidence B Evidence comes only from one crossover randomized placebo-controlled trial which supports the use of IVIg in HIV-associated thrombocytopenia, especially when platelet count is very low or the risk of bleeding is high (strength of recommendation IIa). Level of evidence B IVIg is not used for the treatment of CMV infection but may be helpful in treatment of hemophagocytic syndrome related to CMV and other viruses (see hematology section); there is some evidence for its effectiveness in preventing seroconversion in transplant patients who are immunosuppressed (strength of recommendation IIa). ./cache/cord-006435-4o8uu6d5.txt ./txt/cord-006435-4o8uu6d5.txt