id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274121-3w6kc0c9	Ramiro, Sofia	Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study	2020-07-20		.txt	text/plain	5757	267	47	Objectives To prospectively investigate in patients with severe coVid-19-associated cytokine storm syndrome (css) whether an intensive course of glucocorticoids with or without tocilizumab accelerates clinical improvement, reduces mortality and prevents invasive mechanical ventilation, in comparison with a historic control group of patients who received supportive care only. Objectives To prospectively investigate in patients with severe coVid-19-associated cytokine storm syndrome (css) whether an intensive course of glucocorticoids with or without tocilizumab accelerates clinical improvement, reduces mortality and prevents invasive mechanical ventilation, in comparison with a historic control group of patients who received supportive care only. ► A strategy involving a course of high-dose glucocorticoids, followed by tocilizumab if needed, has shown to accelerate respiratory recovery, lower hospital mortality and reduce the likelihood of invasive mechanical ventilation compared with supportive care only in COVID-19-associated CSS.	./cache/cord-274121-3w6kc0c9.txt	./txt/cord-274121-3w6kc0c9.txt