id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294624-d71za6hi	Kapepula, Paulin M.	Artemisia Spp. Derivatives for COVID-19 Treatment: Anecdotal Use, Political Hype, Treatment Potential, Challenges, and Road Map to Randomized Clinical Trials	2020-07-23		.txt	text/plain	2138	129	42	authors: Kapepula, Paulin M.; Kabengele, Jimmy K.; Kingombe, Micheline; Van Bambeke, Françoise; Tulkens, Paul M.; Sadiki Kishabongo, Antoine; Decloedt, Eric; Zumla, Adam; Tiberi, Simon; Suleman, Fatima; Tshilolo, Léon; Muyembe-TamFum, Jean-Jacques; Zumla, Alimuddin; Nachega, Jean B. Derivatives from the herb Artemisia annua have been used as traditional medicine over centuries for the treatment of fevers, malaria, and respiratory tract infections. This highlights the urgent need for further research on herbal compounds to evaluate efficacy through controlled trials, and for efficacious compounds, to establish the active ingredients, develop formulations and dosing, and define pharmacokinetics, toxicology, and safety to enable drug development. 6, 7 Among many, derivatives from the herb Artemisia annua (Figure 1 ) have been used as traditional medicine over centuries for the treatment of fevers, malaria, and respiratory tract infections. Annua for COVID-19 following claims from politicians and others in low-income countries highlights the need for hard data to establish the active ingredients; develop formulations and dosing; define the pharmacokinetics, toxicology, and safety; and evaluate efficacy through controlled trials.	./cache/cord-294624-d71za6hi.txt	./txt/cord-294624-d71za6hi.txt