id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-314932-edf9xjwr	Yan, Junqiang	Research Progress of Drug Treatment in Novel Coronavirus Pneumonia	2020-05-13		.txt	text/plain	2940	161	41	Studies have found that 2019-nCoV is a single-stranded RNA beta coronavirus similar to SARS and MERS (12) , so current treatment is mainly based on the treatment experience of these two diseases (13) and further development of new targeted drugs. Currently, the drugs studied for the treatment of 2019-nCoV mainly include antivirals, antimalarials, glucocorticoids, plasma therapy, biological agents, and traditional Chinese medicine, among which lopinavir/ritonavir, ribavirin, remdesivir, chloroquine phosphate, and interferon are the main drugs. Recent studies have shown that chloroquine can inhibit 2019-nCoV by increasing the endosome pH required for viral cell fusion (26) , and its antiviral and antiinflammatory activity considerations are also involved (36) . New research shows that interferon-α nebulization, injection of interferon-α2b (57) , and α-interferon combined with lopinavir/ritonavir drugs (58) may be applicable to the current treatment of 2019-nCoV infection. Current studies have shown that the drug treatment of 2019-nCoV-related pneumonia mainly includes antivirals, antimalarials, and interferon. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro	./cache/cord-314932-edf9xjwr.txt	./txt/cord-314932-edf9xjwr.txt