id author title date pages extension mime words sentences flesch summary cache txt cord-336462-7dltsav4 Trovik, Linn Hereide Hemophagocytic lymphohistiocytosis and miliary tuberculosis in a previously healthy individual: a case report 2020-11-11 .txt text/plain 4235 219 36 Here we describe the clinical features, laboratory parameters, diagnostic workup, management and outcome data of a previously healthy 54-year-old man diagnosed with HLH secondary to tuberculosis. CONCLUSIONS: We present one of few published cases of a patient who survived HLH triggered by miliary tuberculosis. Hemophagocytic lymphohistiocytosis (HLH) is an uncommon hematologic disorder characterized by an uncontrolled immune response with organ infiltration of lymphocytes and histiocytes, and organ damage caused by excessive production of pro-inflammatory cytokines [1] [2] [3] [4] [5] [6] . Results from bone marrow biopsy later revealed an expanded erythropoiesis, increased number of histiocytic cells with phagocytosed lymphocytes and nuclear debris (hemophagocytosis) and granulomas that supported the diagnosis of HLH and TB, respectively (Fig. 4) . Treatment outcomes and prognostic factors in adult patients with secondary hemophagocytic lymphohistiocytosis not associated with malignancy Tuberculosis-associated hemophagocytic lymphohistiocytosis with initial presentation of fever of unknown origin in a general hospital: an analysis of 8 clinical cases ./cache/cord-336462-7dltsav4.txt ./txt/cord-336462-7dltsav4.txt