id author title date pages extension mime words sentences flesch summary cache txt cord-351510-8m4930bc Aquino, Yves S J Hydroxychloroquine and COVID-19: critiquing the impact of disease public profile on policy and clinical decision-making 2020-07-09 .txt text/plain 5065 263 48 In particular, we briefly examine the dangers of a heightened public profile in magnifying the inequality of diseases and undermining three key ethical concepts, namely (1) evidence-based practice, (2) sustainable allocation and (3) meaningful consent. 28 In the next three sections, we elaborate the ways in which one disease's public profile, such as COVID-19's, can become so extraordinary that it undermines evidence-based clinical practice, drives unsustainable resource allocation and authorises structural forms of coercive consent. 32 Although there are several morally justifiable reasons for off-label use in general clinical practice, our analysis focusses on the influence of disease public profile on the unapproved or emergency use of HCQ for COVID-19 without sufficient scientific evidence. In this article, we argued that the case of HCQ being touted as potential COVID-19 treatment demonstrates the dangers of a disease's public profile becoming the overarching influence in healthcare decision-making. ./cache/cord-351510-8m4930bc.txt ./txt/cord-351510-8m4930bc.txt