id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-048447-chz8luni	Duffett, Mark	Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis	2007-06-15		.txt	text/plain	3996	215	38	The primary objective of the systematic review is to assess the effect of the administration of pulmonary surfactant compared with no therapy or with placebo on all-cause mortality (at or before hospital discharge) in mechanically ventilated children with acute respiratory failure. We used the following characteristics to assess the methodologic quality: allocation concealment (sealed envelopes or central randomization were considered adequate), blinding (which of the trial personnel and caregivers were blinded, and the methods used to ensure blinding), completeness of followup (assessed by the number of patients randomized for whom there were no outcomes), similarity of the groups at baseline (with respect to known prognostic factors: age, aetiology, severity of illness as measured by the Pediatric Risk of Mortality score, and immunosuppression), whether a standard or recommended strategy for mechanical ventilation was used, and whether a priori criteria for the use of co-interventions were used.	./cache/cord-048447-chz8luni.txt	./txt/cord-048447-chz8luni.txt