id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266573-vfl08i2p	Largent, Emily A	Paying Participants in COVID-19 Trials	2020-05-29		.txt	text/plain	3636	157	36	Given increased risk of undue influence against pandemic background conditions, incentive payment should be avoided unless essential to recruitment and retention in important trials whose social value outweighs this risk. Given the pandemic's devastating economic effects, as well as the fact that risks may be higher or more uncertain in COVID-19 trials than in nonpandemic research, there is an increased likelihood of undue influence stemming from incentive payments. Rather, in light of pandemic circumstances-similar features of which may be replicated in other contexts, including research conducted in low-and middle-income countries or with participants whose nonresearch options are limited even in the absence of a pandemic-offers of compensation may raise ethical concerns akin to incentives [14] . Acknowledging this challenge, the best IRBs can do is to minimize the possibility of undue influence for trial participants on the whole by making it unlikely for research participation to constitute an objectively unreasonable choice for members of the target study population.	./cache/cord-266573-vfl08i2p.txt	./txt/cord-266573-vfl08i2p.txt