id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-279637-n8acd6hj	van der Plas, J.L.	How to expedite early phase SARS‐CoV‐2 vaccine trials in pandemic setting – a practical perspective	2020-06-19		.txt	text/plain	986	62	36	authors: van der Plas, J.L.; Roestenberg, M.; Cohen, A.F.; Kamerling, I.M.C. title: How to expedite early phase SARS‐CoV‐2 vaccine trials in pandemic setting – a practical perspective After preclinical studies and manufacturing processes, a rate-limiting step in vaccine development is the conduct of clinical trials. In the current COVID-19 pandemic it is more important than ever to identify and select the most promising vaccine candidates as early as possible and stop clinical development for failing candidates to avoid wasting valuable time and resources. Here, we discuss several practical suggestions that could accelerate early phase vaccine trials in the COVID-19 pandemic. Recruitment and screening of participants are time consuming activities in early phase clinical trials. Significant time can be saved if potential participants can be identified, counseled and general health status assessed before the formal clinical trial approval.	./cache/cord-279637-n8acd6hj.txt	./txt/cord-279637-n8acd6hj.txt