id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-282261-wcmc5mh6	Rhodus, Elizabeth K.	COVID-19 and geriatric clinical trials research	2020-09-16		.txt	text/plain	2256	104	34	The COVID-19 crisis affects every aspect of clinical trial research engagement including: recruitment and retention; ability to ensure participant safety while engaged in experimental interventions; study procedures, including consideration of remote assessments, impact on populations with health disparities, and generalizability of future results; outcome measures, including biomarker assessment; impact on the clinical trial workforce, including attrition; impact on dissemination of results and scientific collaborations, which move the clinical trial infrastructure forward; current and future funding allocations; and regulatory considerations in regards to management of altered study conduct and change of outcome measures (Fig. 1) . The purpose of this article is to highlight the impact of disasters such as the COVID-19 pandemic on geriatric clinical trials research and propose approaches for the scientific community to continue pushing forward. The vulnerability of older adults to COVID-19 is a critical reminder for the need to prepare for disasters during clinical trial design.	./cache/cord-282261-wcmc5mh6.txt	./txt/cord-282261-wcmc5mh6.txt