id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286288-gduhterq	Spitzer, Ernest	Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019	2020-05-01		.txt	text/plain	2758	157	36	Nevertheless, new or ongoing clinical trials, not related to the disease itself, remain important for the development of new therapies, and require interactions among patients, clinicians and research personnel, which is challenging, given isolation measures. Trials in patient populations with acute presentations (e.g. ST-elevation MI [STEMI]) may identify potentially suitable trial candidates; however, the capacity to comply with study procedures needs to be assessed, as well as considerations related to patient safety during follow-up. Participants in the follow-up phase (when they are generally at home) constitute a higher-risk population in the Reduced capacity at investigational sites will impact on availability to perform study visits (or phone calls) to assess and confirm eligibility, enter data in electronic case report forms (eCRFs), to report (serious) adverse events and to follow the protocol in general. The participation of several committees in clinical trials ensures proper scientific and operational oversight, data integrity and quality, as well as patient safety.	./cache/cord-286288-gduhterq.txt	./txt/cord-286288-gduhterq.txt