id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324607-rpwccvqi	Rojek, Amanda M	Core Minimal Datasets to Advance Clinical Research for Priority Epidemic Diseases	2020-02-15		.txt	text/plain	1260	63	39	Among the noteworthy successes of vaccine trials, and the commendable efforts to implement clinical treatment trials during Ebola outbreaks, we should also focus on strengthening the collection and curation of epidemiological and observational data that can improve the conception and design of clinical research. Table 1 identifies some key domains that could contribute to a core minimal dataset that informs clinical trial design for each priority pathogen. While these data have their most important benefits in improving patient management (through better recognition of disease complications and informing supportive care) and public health control, patient-based data are also used to determine key parameters for clinical trials, such as the inclusion criteria, the nature and rate of clinically relevant outcomes, and potential confounders. A systematic review and meta-analysis of patient data from the west Africa (2013-16) Ebola virus disease epidemic	./cache/cord-324607-rpwccvqi.txt	./txt/cord-324607-rpwccvqi.txt