id	sid	tid	token	lemma	pos
cord-309582-ihrj84hr	1	1	key	key	JJ
cord-309582-ihrj84hr	1	2	:	:	:
cord-309582-ihrj84hr	1	3	cord-309582-ihrj84hr	cord-309582-ihrj84hr	JJ
cord-309582-ihrj84hr	1	4	authors	author	NNS
cord-309582-ihrj84hr	1	5	:	:	:
cord-309582-ihrj84hr	1	6	AlNaamani	AlNaamani	NNP
cord-309582-ihrj84hr	1	7	,	,	,
cord-309582-ihrj84hr	1	8	Khalid	Khalid	NNP
cord-309582-ihrj84hr	1	9	;	;	:
cord-309582-ihrj84hr	1	10	AlSinani	AlSinani	NNP
cord-309582-ihrj84hr	1	11	,	,	,
cord-309582-ihrj84hr	1	12	Siham	Siham	NNP
cord-309582-ihrj84hr	1	13	;	;	:
cord-309582-ihrj84hr	1	14	Barkun	Barkun	NNP
cord-309582-ihrj84hr	1	15	,	,	,
cord-309582-ihrj84hr	1	16	Alan	Alan	NNP
cord-309582-ihrj84hr	1	17	N	N	NNP
cord-309582-ihrj84hr	2	1	title	title	NN
cord-309582-ihrj84hr	2	2	:	:	:
cord-309582-ihrj84hr	3	1	Medical	medical	JJ
cord-309582-ihrj84hr	3	2	research	research	NN
cord-309582-ihrj84hr	3	3	during	during	IN
cord-309582-ihrj84hr	3	4	the	the	DT
cord-309582-ihrj84hr	3	5	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	3	6	pandemic	pandemic	NN
cord-309582-ihrj84hr	3	7	date	date	NN
cord-309582-ihrj84hr	3	8	:	:	:
cord-309582-ihrj84hr	3	9	2020	2020	CD
cord-309582-ihrj84hr	3	10	-	-	HYPH
cord-309582-ihrj84hr	3	11	08	08	CD
cord-309582-ihrj84hr	3	12	-	-	HYPH
cord-309582-ihrj84hr	3	13	06	06	CD
cord-309582-ihrj84hr	3	14	journal	journal	NN
cord-309582-ihrj84hr	3	15	:	:	:
cord-309582-ihrj84hr	4	1	World	World	NNP
cord-309582-ihrj84hr	4	2	J	J	NNP
cord-309582-ihrj84hr	4	3	Clin	Clin	NNP
cord-309582-ihrj84hr	4	4	Cases	case	NNS
cord-309582-ihrj84hr	5	1	DOI	DOI	NNP
cord-309582-ihrj84hr	5	2	:	:	:
cord-309582-ihrj84hr	6	1	10.12998	10.12998	CD
cord-309582-ihrj84hr	6	2	/	/	SYM
cord-309582-ihrj84hr	6	3	wjcc.v8.i15.3156	wjcc.v8.i15.3156	NNP
cord-309582-ihrj84hr	6	4	sha	sha	NNP
cord-309582-ihrj84hr	6	5	:	:	:
cord-309582-ihrj84hr	6	6	d17eafe85bfe3b2c41b7754ac0b8b75e507d31e5	d17eafe85bfe3b2c41b7754ac0b8b75e507d31e5	NNS
cord-309582-ihrj84hr	6	7	doc_id	doc_id	CD
cord-309582-ihrj84hr	6	8	:	:	:
cord-309582-ihrj84hr	6	9	309582	309582	CD
cord-309582-ihrj84hr	6	10	cord_uid	cord_uid	NNS
cord-309582-ihrj84hr	6	11	:	:	:
cord-309582-ihrj84hr	7	1	ihrj84hr	ihrj84hr	NNP
cord-309582-ihrj84hr	8	1	The	the	DT
cord-309582-ihrj84hr	8	2	current	current	JJ
cord-309582-ihrj84hr	8	3	pandemic	pandemic	NN
cord-309582-ihrj84hr	8	4	of	of	IN
cord-309582-ihrj84hr	8	5	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	8	6	disease	disease	NN
cord-309582-ihrj84hr	8	7	2019	2019	CD
cord-309582-ihrj84hr	8	8	(	(	-LRB-
cord-309582-ihrj84hr	8	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	8	10	)	)	-RRB-
cord-309582-ihrj84hr	8	11	which	which	WDT
cord-309582-ihrj84hr	8	12	was	be	VBD
cord-309582-ihrj84hr	8	13	first	first	RB
cord-309582-ihrj84hr	8	14	detected	detect	VBN
cord-309582-ihrj84hr	8	15	in	in	IN
cord-309582-ihrj84hr	8	16	Wuhan	Wuhan	NNP
cord-309582-ihrj84hr	8	17	,	,	,
cord-309582-ihrj84hr	8	18	China	China	NNP
cord-309582-ihrj84hr	8	19	in	in	IN
cord-309582-ihrj84hr	8	20	December	December	NNP
cord-309582-ihrj84hr	8	21	2019	2019	CD
cord-309582-ihrj84hr	8	22	is	be	VBZ
cord-309582-ihrj84hr	8	23	caused	cause	VBN
cord-309582-ihrj84hr	8	24	by	by	IN
cord-309582-ihrj84hr	8	25	the	the	DT
cord-309582-ihrj84hr	8	26	novel	novel	JJ
cord-309582-ihrj84hr	8	27	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	8	28	named	name	VBN
cord-309582-ihrj84hr	8	29	severe	severe	JJ
cord-309582-ihrj84hr	8	30	acute	acute	JJ
cord-309582-ihrj84hr	8	31	respiratory	respiratory	JJ
cord-309582-ihrj84hr	8	32	syndrome	syndrome	NN
cord-309582-ihrj84hr	8	33	coronavirus-2	coronavirus-2	NNP
cord-309582-ihrj84hr	8	34	(	(	-LRB-
cord-309582-ihrj84hr	8	35	SARS	SARS	NNP
cord-309582-ihrj84hr	8	36	-	-	HYPH
cord-309582-ihrj84hr	8	37	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	8	38	)	)	-RRB-
cord-309582-ihrj84hr	8	39	.	.	.
cord-309582-ihrj84hr	9	1	The	the	DT
cord-309582-ihrj84hr	9	2	virus	virus	NN
cord-309582-ihrj84hr	9	3	has	have	VBZ
cord-309582-ihrj84hr	9	4	quickly	quickly	RB
cord-309582-ihrj84hr	9	5	spread	spread	VBN
cord-309582-ihrj84hr	9	6	to	to	IN
cord-309582-ihrj84hr	9	7	a	a	DT
cord-309582-ihrj84hr	9	8	large	large	JJ
cord-309582-ihrj84hr	9	9	number	number	NN
cord-309582-ihrj84hr	9	10	of	of	IN
cord-309582-ihrj84hr	9	11	countries	country	NNS
cord-309582-ihrj84hr	9	12	leading	lead	VBG
cord-309582-ihrj84hr	9	13	to	to	IN
cord-309582-ihrj84hr	9	14	a	a	DT
cord-309582-ihrj84hr	9	15	great	great	JJ
cord-309582-ihrj84hr	9	16	number	number	NN
cord-309582-ihrj84hr	9	17	of	of	IN
cord-309582-ihrj84hr	9	18	deaths	death	NNS
cord-309582-ihrj84hr	9	19	.	.	.
cord-309582-ihrj84hr	10	1	Unfortunately	unfortunately	RB
cord-309582-ihrj84hr	10	2	,	,	,
cord-309582-ihrj84hr	10	3	till	till	IN
cord-309582-ihrj84hr	10	4	today	today	NN
cord-309582-ihrj84hr	10	5	there	there	EX
cord-309582-ihrj84hr	10	6	is	be	VBZ
cord-309582-ihrj84hr	10	7	no	no	DT
cord-309582-ihrj84hr	10	8	specific	specific	JJ
cord-309582-ihrj84hr	10	9	treatment	treatment	NN
cord-309582-ihrj84hr	10	10	or	or	CC
cord-309582-ihrj84hr	10	11	vaccination	vaccination	NN
cord-309582-ihrj84hr	10	12	for	for	IN
cord-309582-ihrj84hr	10	13	SARS	SARS	NNP
cord-309582-ihrj84hr	10	14	-	-	HYPH
cord-309582-ihrj84hr	10	15	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	10	16	.	.	.
cord-309582-ihrj84hr	11	1	Most	Most	JJS
cord-309582-ihrj84hr	11	2	of	of	IN
cord-309582-ihrj84hr	11	3	the	the	DT
cord-309582-ihrj84hr	11	4	suggested	suggest	VBN
cord-309582-ihrj84hr	11	5	treatment	treatment	NN
cord-309582-ihrj84hr	11	6	medications	medication	NNS
cord-309582-ihrj84hr	11	7	are	be	VBP
cord-309582-ihrj84hr	11	8	based	base	VBN
cord-309582-ihrj84hr	11	9	on	on	IN
cord-309582-ihrj84hr	11	10	in	in	IN
cord-309582-ihrj84hr	11	11	vitro	vitro	FW
cord-309582-ihrj84hr	11	12	laboratory	laboratory	NN
cord-309582-ihrj84hr	11	13	investigations	investigation	NNS
cord-309582-ihrj84hr	11	14	,	,	,
cord-309582-ihrj84hr	11	15	experimental	experimental	JJ
cord-309582-ihrj84hr	11	16	animal	animal	NN
cord-309582-ihrj84hr	11	17	models	model	NNS
cord-309582-ihrj84hr	11	18	,	,	,
cord-309582-ihrj84hr	11	19	or	or	CC
cord-309582-ihrj84hr	11	20	previous	previous	JJ
cord-309582-ihrj84hr	11	21	clinical	clinical	JJ
cord-309582-ihrj84hr	11	22	experience	experience	NN
cord-309582-ihrj84hr	11	23	in	in	IN
cord-309582-ihrj84hr	11	24	treating	treat	VBG
cord-309582-ihrj84hr	11	25	similar	similar	JJ
cord-309582-ihrj84hr	11	26	viruses	virus	NNS
cord-309582-ihrj84hr	11	27	such	such	JJ
cord-309582-ihrj84hr	11	28	as	as	IN
cord-309582-ihrj84hr	11	29	SARS	SARS	NNP
cord-309582-ihrj84hr	11	30	-	-	HYPH
cord-309582-ihrj84hr	11	31	CoV-1	CoV-1	NNP
cord-309582-ihrj84hr	11	32	or	or	CC
cord-309582-ihrj84hr	11	33	other	other	JJ
cord-309582-ihrj84hr	11	34	retroviral	retroviral	JJ
cord-309582-ihrj84hr	11	35	infections	infection	NNS
cord-309582-ihrj84hr	11	36	.	.	.
cord-309582-ihrj84hr	12	1	The	the	DT
cord-309582-ihrj84hr	12	2	running	running	NN
cord-309582-ihrj84hr	12	3	of	of	IN
cord-309582-ihrj84hr	12	4	any	any	DT
cord-309582-ihrj84hr	12	5	clinical	clinical	JJ
cord-309582-ihrj84hr	12	6	trial	trial	NN
cord-309582-ihrj84hr	12	7	during	during	IN
cord-309582-ihrj84hr	12	8	a	a	DT
cord-309582-ihrj84hr	12	9	pandemic	pandemic	NN
cord-309582-ihrj84hr	12	10	is	be	VBZ
cord-309582-ihrj84hr	12	11	affected	affect	VBN
cord-309582-ihrj84hr	12	12	at	at	IN
cord-309582-ihrj84hr	12	13	multiple	multiple	JJ
cord-309582-ihrj84hr	12	14	levels	level	NNS
cord-309582-ihrj84hr	12	15	.	.	.
cord-309582-ihrj84hr	13	1	Reasons	reason	NNS
cord-309582-ihrj84hr	13	2	for	for	IN
cord-309582-ihrj84hr	13	3	this	this	DT
cord-309582-ihrj84hr	13	4	include	include	VBP
cord-309582-ihrj84hr	13	5	patient	patient	JJ
cord-309582-ihrj84hr	13	6	hesitancy	hesitancy	NN
cord-309582-ihrj84hr	13	7	or	or	CC
cord-309582-ihrj84hr	13	8	inability	inability	NN
cord-309582-ihrj84hr	13	9	to	to	TO
cord-309582-ihrj84hr	13	10	continue	continue	VB
cord-309582-ihrj84hr	13	11	investigative	investigative	JJ
cord-309582-ihrj84hr	13	12	treatments	treatment	NNS
cord-309582-ihrj84hr	13	13	due	due	JJ
cord-309582-ihrj84hr	13	14	to	to	IN
cord-309582-ihrj84hr	13	15	self	self	NN
cord-309582-ihrj84hr	13	16	-	-	HYPH
cord-309582-ihrj84hr	13	17	isolation	isolation	NN
cord-309582-ihrj84hr	13	18	/	/	SYM
cord-309582-ihrj84hr	13	19	quarantine	quarantine	NN
cord-309582-ihrj84hr	13	20	,	,	,
cord-309582-ihrj84hr	13	21	or	or	CC
cord-309582-ihrj84hr	13	22	limited	limited	JJ
cord-309582-ihrj84hr	13	23	access	access	NN
cord-309582-ihrj84hr	13	24	to	to	IN
cord-309582-ihrj84hr	13	25	public	public	JJ
cord-309582-ihrj84hr	13	26	places	place	NNS
cord-309582-ihrj84hr	13	27	(	(	-LRB-
cord-309582-ihrj84hr	13	28	including	include	VBG
cord-309582-ihrj84hr	13	29	hospitals	hospital	NNS
cord-309582-ihrj84hr	13	30	)	)	-RRB-
cord-309582-ihrj84hr	13	31	.	.	.
cord-309582-ihrj84hr	14	1	Additional	additional	JJ
cord-309582-ihrj84hr	14	2	barriers	barrier	NNS
cord-309582-ihrj84hr	14	3	relate	relate	VBP
cord-309582-ihrj84hr	14	4	to	to	IN
cord-309582-ihrj84hr	14	5	health	health	NN
cord-309582-ihrj84hr	14	6	care	care	NN
cord-309582-ihrj84hr	14	7	professionals	professional	NNS
cord-309582-ihrj84hr	14	8	being	be	VBG
cord-309582-ihrj84hr	14	9	committed	commit	VBN
cord-309582-ihrj84hr	14	10	to	to	IN
cord-309582-ihrj84hr	14	11	other	other	JJ
cord-309582-ihrj84hr	14	12	critical	critical	JJ
cord-309582-ihrj84hr	14	13	tasks	task	NNS
cord-309582-ihrj84hr	14	14	or	or	CC
cord-309582-ihrj84hr	14	15	quarantining	quarantine	VBG
cord-309582-ihrj84hr	14	16	themselves	-PRON-	PRP
cord-309582-ihrj84hr	14	17	due	due	JJ
cord-309582-ihrj84hr	14	18	to	to	IN
cord-309582-ihrj84hr	14	19	contact	contact	NN
cord-309582-ihrj84hr	14	20	with	with	IN
cord-309582-ihrj84hr	14	21	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	14	22	positive	positive	JJ
cord-309582-ihrj84hr	14	23	patients	patient	NNS
cord-309582-ihrj84hr	14	24	.	.	.
cord-309582-ihrj84hr	15	1	The	the	DT
cord-309582-ihrj84hr	15	2	best	good	JJS
cord-309582-ihrj84hr	15	3	research	research	NN
cord-309582-ihrj84hr	15	4	approaches	approach	NNS
cord-309582-ihrj84hr	15	5	are	be	VBP
cord-309582-ihrj84hr	15	6	those	those	DT
cord-309582-ihrj84hr	15	7	that	that	WDT
cord-309582-ihrj84hr	15	8	adapt	adapt	VBP
cord-309582-ihrj84hr	15	9	to	to	IN
cord-309582-ihrj84hr	15	10	such	such	JJ
cord-309582-ihrj84hr	15	11	external	external	JJ
cord-309582-ihrj84hr	15	12	unplanned	unplanned	JJ
cord-309582-ihrj84hr	15	13	obstacles	obstacle	NNS
cord-309582-ihrj84hr	15	14	.	.	.
cord-309582-ihrj84hr	16	1	Ongoing	ongoing	JJ
cord-309582-ihrj84hr	16	2	clinical	clinical	JJ
cord-309582-ihrj84hr	16	3	trials	trial	NNS
cord-309582-ihrj84hr	16	4	before	before	IN
cord-309582-ihrj84hr	16	5	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	16	6	pandemic	pandemic	NN
cord-309582-ihrj84hr	16	7	have	have	VBP
cord-309582-ihrj84hr	16	8	the	the	DT
cord-309582-ihrj84hr	16	9	potential	potential	NN
cord-309582-ihrj84hr	16	10	for	for	IN
cord-309582-ihrj84hr	16	11	identifying	identify	VBG
cord-309582-ihrj84hr	16	12	important	important	JJ
cord-309582-ihrj84hr	16	13	therapies	therapy	NNS
cord-309582-ihrj84hr	16	14	in	in	IN
cord-309582-ihrj84hr	16	15	the	the	DT
cord-309582-ihrj84hr	16	16	long	long	JJ
cord-309582-ihrj84hr	16	17	-	-	HYPH
cord-309582-ihrj84hr	16	18	term	term	NN
cord-309582-ihrj84hr	16	19	if	if	IN
cord-309582-ihrj84hr	16	20	they	-PRON-	PRP
cord-309582-ihrj84hr	16	21	can	can	MD
cord-309582-ihrj84hr	16	22	be	be	VB
cord-309582-ihrj84hr	16	23	completed	complete	VBN
cord-309582-ihrj84hr	16	24	as	as	IN
cord-309582-ihrj84hr	16	25	planned	plan	VBN
cord-309582-ihrj84hr	16	26	.	.	.
cord-309582-ihrj84hr	17	1	However	however	RB
cord-309582-ihrj84hr	17	2	,	,	,
cord-309582-ihrj84hr	17	3	these	these	DT
cord-309582-ihrj84hr	17	4	clinical	clinical	JJ
cord-309582-ihrj84hr	17	5	trials	trial	NNS
cord-309582-ihrj84hr	17	6	may	may	MD
cord-309582-ihrj84hr	17	7	require	require	VB
cord-309582-ihrj84hr	17	8	modifications	modification	NNS
cord-309582-ihrj84hr	17	9	due	due	JJ
cord-309582-ihrj84hr	17	10	a	a	DT
cord-309582-ihrj84hr	17	11	pandemic	pandemic	NN
cord-309582-ihrj84hr	17	12	such	such	JJ
cord-309582-ihrj84hr	17	13	as	as	IN
cord-309582-ihrj84hr	17	14	this	this	DT
cord-309582-ihrj84hr	17	15	one	one	NN
cord-309582-ihrj84hr	17	16	to	to	TO
cord-309582-ihrj84hr	17	17	ensure	ensure	VB
cord-309582-ihrj84hr	17	18	the	the	DT
cord-309582-ihrj84hr	17	19	rights	right	NNS
cord-309582-ihrj84hr	17	20	,	,	,
cord-309582-ihrj84hr	17	21	safety	safety	NN
cord-309582-ihrj84hr	17	22	,	,	,
cord-309582-ihrj84hr	17	23	and	and	CC
cord-309582-ihrj84hr	17	24	wellbeing	wellbeing	NN
cord-309582-ihrj84hr	17	25	of	of	IN
cord-309582-ihrj84hr	17	26	participants	participant	NNS
cord-309582-ihrj84hr	17	27	as	as	RB
cord-309582-ihrj84hr	17	28	well	well	RB
cord-309582-ihrj84hr	17	29	as	as	IN
cord-309582-ihrj84hr	17	30	medical	medical	JJ
cord-309582-ihrj84hr	17	31	staff	staff	NN
cord-309582-ihrj84hr	17	32	involved	involve	VBN
cord-309582-ihrj84hr	17	33	in	in	IN
cord-309582-ihrj84hr	17	34	the	the	DT
cord-309582-ihrj84hr	17	35	conduction	conduction	NN
cord-309582-ihrj84hr	17	36	of	of	IN
cord-309582-ihrj84hr	17	37	clinical	clinical	JJ
cord-309582-ihrj84hr	17	38	trials	trial	NNS
cord-309582-ihrj84hr	17	39	.	.	.
cord-309582-ihrj84hr	18	1	Clinical	clinical	JJ
cord-309582-ihrj84hr	18	2	trials	trial	NNS
cord-309582-ihrj84hr	18	3	initiated	initiate	VBD
cord-309582-ihrj84hr	18	4	during	during	IN
cord-309582-ihrj84hr	18	5	the	the	DT
cord-309582-ihrj84hr	18	6	pandemic	pandemic	NN
cord-309582-ihrj84hr	18	7	must	must	MD
cord-309582-ihrj84hr	18	8	be	be	VB
cord-309582-ihrj84hr	18	9	time	time	NN
cord-309582-ihrj84hr	18	10	-	-	HYPH
cord-309582-ihrj84hr	18	11	efficient	efficient	JJ
cord-309582-ihrj84hr	18	12	and	and	CC
cord-309582-ihrj84hr	18	13	flexible	flexible	JJ
cord-309582-ihrj84hr	18	14	due	due	IN
cord-309582-ihrj84hr	18	15	to	to	IN
cord-309582-ihrj84hr	18	16	high	high	JJ
cord-309582-ihrj84hr	18	17	contagiousness	contagiousness	NN
cord-309582-ihrj84hr	18	18	of	of	IN
cord-309582-ihrj84hr	18	19	severe	severe	JJ
cord-309582-ihrj84hr	18	20	acute	acute	JJ
cord-309582-ihrj84hr	18	21	respiratory	respiratory	JJ
cord-309582-ihrj84hr	18	22	syndrome	syndrome	NN
cord-309582-ihrj84hr	18	23	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	18	24	2	2	CD
cord-309582-ihrj84hr	18	25	,	,	,
cord-309582-ihrj84hr	18	26	the	the	DT
cord-309582-ihrj84hr	18	27	significant	significant	JJ
cord-309582-ihrj84hr	18	28	number	number	NN
cord-309582-ihrj84hr	18	29	of	of	IN
cord-309582-ihrj84hr	18	30	reported	report	VBN
cord-309582-ihrj84hr	18	31	deaths	death	NNS
cord-309582-ihrj84hr	18	32	,	,	,
cord-309582-ihrj84hr	18	33	and	and	CC
cord-309582-ihrj84hr	18	34	time	time	NN
cord-309582-ihrj84hr	18	35	constraints	constraint	NNS
cord-309582-ihrj84hr	18	36	needed	need	VBN
cord-309582-ihrj84hr	18	37	to	to	TO
cord-309582-ihrj84hr	18	38	perform	perform	VB
cord-309582-ihrj84hr	18	39	high	high	JJ
cord-309582-ihrj84hr	18	40	quality	quality	NN
cord-309582-ihrj84hr	18	41	clinical	clinical	JJ
cord-309582-ihrj84hr	18	42	trials	trial	NNS
cord-309582-ihrj84hr	18	43	,	,	,
cord-309582-ihrj84hr	18	44	enrolling	enrol	VBG
cord-309582-ihrj84hr	18	45	adequate	adequate	JJ
cord-309582-ihrj84hr	18	46	sample	sample	NN
cord-309582-ihrj84hr	18	47	sizes	size	NNS
cord-309582-ihrj84hr	18	48	.	.	.
cord-309582-ihrj84hr	19	1	Collaboration	collaboration	NN
cord-309582-ihrj84hr	19	2	between	between	IN
cord-309582-ihrj84hr	19	3	different	different	JJ
cord-309582-ihrj84hr	19	4	countries	country	NNS
cord-309582-ihrj84hr	19	5	as	as	RB
cord-309582-ihrj84hr	19	6	well	well	RB
cord-309582-ihrj84hr	19	7	as	as	IN
cord-309582-ihrj84hr	19	8	implementation	implementation	NN
cord-309582-ihrj84hr	19	9	of	of	IN
cord-309582-ihrj84hr	19	10	innovative	innovative	JJ
cord-309582-ihrj84hr	19	11	clinical	clinical	JJ
cord-309582-ihrj84hr	19	12	trial	trial	NN
cord-309582-ihrj84hr	19	13	designs	design	NNS
cord-309582-ihrj84hr	19	14	are	be	VBP
cord-309582-ihrj84hr	19	15	essential	essential	JJ
cord-309582-ihrj84hr	19	16	to	to	TO
cord-309582-ihrj84hr	19	17	successfully	successfully	RB
cord-309582-ihrj84hr	19	18	complete	complete	VB
cord-309582-ihrj84hr	19	19	such	such	JJ
cord-309582-ihrj84hr	19	20	initiatives	initiative	NNS
cord-309582-ihrj84hr	19	21	during	during	IN
cord-309582-ihrj84hr	19	22	the	the	DT
cord-309582-ihrj84hr	19	23	current	current	JJ
cord-309582-ihrj84hr	19	24	pandemic	pandemic	NN
cord-309582-ihrj84hr	19	25	.	.	.
cord-309582-ihrj84hr	20	1	Studies	study	NNS
cord-309582-ihrj84hr	20	2	looking	look	VBG
cord-309582-ihrj84hr	20	3	at	at	IN
cord-309582-ihrj84hr	20	4	the	the	DT
cord-309582-ihrj84hr	20	5	long	long	JJ
cord-309582-ihrj84hr	20	6	term	term	NN
cord-309582-ihrj84hr	20	7	sequalae	sequalae	NNP
cord-309582-ihrj84hr	20	8	of	of	IN
cord-309582-ihrj84hr	20	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	20	10	are	be	VBP
cord-309582-ihrj84hr	20	11	also	also	RB
cord-309582-ihrj84hr	20	12	of	of	IN
cord-309582-ihrj84hr	20	13	importance	importance	NN
cord-309582-ihrj84hr	20	14	as	as	IN
cord-309582-ihrj84hr	20	15	recent	recent	JJ
cord-309582-ihrj84hr	20	16	publications	publication	NNS
cord-309582-ihrj84hr	20	17	describe	describe	VBP
cord-309582-ihrj84hr	20	18	multi	multi	JJ
cord-309582-ihrj84hr	20	19	-	-	JJ
cord-309582-ihrj84hr	20	20	organ	organ	JJ
cord-309582-ihrj84hr	20	21	involvement	involvement	NN
cord-309582-ihrj84hr	20	22	.	.	.
cord-309582-ihrj84hr	21	1	Long	long	JJ
cord-309582-ihrj84hr	21	2	term	term	NN
cord-309582-ihrj84hr	21	3	follow	follow	NN
cord-309582-ihrj84hr	21	4	-	-	HYPH
cord-309582-ihrj84hr	21	5	up	up	NN
cord-309582-ihrj84hr	21	6	of	of	IN
cord-309582-ihrj84hr	21	7	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	21	8	survivors	survivor	NNS
cord-309582-ihrj84hr	21	9	is	be	VBZ
cord-309582-ihrj84hr	21	10	thus	thus	RB
cord-309582-ihrj84hr	21	11	also	also	RB
cord-309582-ihrj84hr	21	12	important	important	JJ
cord-309582-ihrj84hr	21	13	to	to	TO
cord-309582-ihrj84hr	21	14	identify	identify	VB
cord-309582-ihrj84hr	21	15	possible	possible	JJ
cord-309582-ihrj84hr	21	16	physical	physical	JJ
cord-309582-ihrj84hr	21	17	and	and	CC
cord-309582-ihrj84hr	21	18	mental	mental	JJ
cord-309582-ihrj84hr	21	19	health	health	NN
cord-309582-ihrj84hr	21	20	sequellae	sequellae	NNS
cord-309582-ihrj84hr	21	21	.	.	.
cord-309582-ihrj84hr	22	1	The	the	DT
cord-309582-ihrj84hr	22	2	current	current	JJ
cord-309582-ihrj84hr	22	3	pandemic	pandemic	NN
cord-309582-ihrj84hr	22	4	of	of	IN
cord-309582-ihrj84hr	22	5	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	22	6	disease	disease	NN
cord-309582-ihrj84hr	22	7	2019	2019	CD
cord-309582-ihrj84hr	22	8	(	(	-LRB-
cord-309582-ihrj84hr	22	9	COVID-	COVID-	NNP
cord-309582-ihrj84hr	22	10	19	19	CD
cord-309582-ihrj84hr	22	11	)	)	-RRB-
cord-309582-ihrj84hr	22	12	which	which	WDT
cord-309582-ihrj84hr	22	13	was	be	VBD
cord-309582-ihrj84hr	22	14	first	first	RB
cord-309582-ihrj84hr	22	15	detected	detect	VBN
cord-309582-ihrj84hr	22	16	in	in	IN
cord-309582-ihrj84hr	22	17	Wuhan	Wuhan	NNP
cord-309582-ihrj84hr	22	18	,	,	,
cord-309582-ihrj84hr	22	19	China	China	NNP
cord-309582-ihrj84hr	22	20	in	in	IN
cord-309582-ihrj84hr	22	21	December	December	NNP
cord-309582-ihrj84hr	22	22	2019	2019	CD
cord-309582-ihrj84hr	22	23	is	be	VBZ
cord-309582-ihrj84hr	22	24	caused	cause	VBN
cord-309582-ihrj84hr	22	25	by	by	IN
cord-309582-ihrj84hr	22	26	the	the	DT
cord-309582-ihrj84hr	22	27	novel	novel	JJ
cord-309582-ihrj84hr	22	28	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	22	29	named	name	VBN
cord-309582-ihrj84hr	22	30	severe	severe	JJ
cord-309582-ihrj84hr	22	31	acute	acute	JJ
cord-309582-ihrj84hr	22	32	respiratory	respiratory	JJ
cord-309582-ihrj84hr	22	33	syndrome	syndrome	NN
cord-309582-ihrj84hr	22	34	coronavirus-2	coronavirus-2	NNP
cord-309582-ihrj84hr	22	35	(	(	-LRB-
cord-309582-ihrj84hr	22	36	SARS	SARS	NNP
cord-309582-ihrj84hr	22	37	-	-	HYPH
cord-309582-ihrj84hr	22	38	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	22	39	)	)	-RRB-
cord-309582-ihrj84hr	22	40	.	.	.
cord-309582-ihrj84hr	23	1	The	the	DT
cord-309582-ihrj84hr	23	2	virus	virus	NN
cord-309582-ihrj84hr	23	3	has	have	VBZ
cord-309582-ihrj84hr	23	4	quickly	quickly	RB
cord-309582-ihrj84hr	23	5	spread	spread	VBN
cord-309582-ihrj84hr	23	6	to	to	IN
cord-309582-ihrj84hr	23	7	a	a	DT
cord-309582-ihrj84hr	23	8	large	large	JJ
cord-309582-ihrj84hr	23	9	number	number	NN
cord-309582-ihrj84hr	23	10	of	of	IN
cord-309582-ihrj84hr	23	11	countries	country	NNS
cord-309582-ihrj84hr	23	12	leading	lead	VBG
cord-309582-ihrj84hr	23	13	to	to	IN
cord-309582-ihrj84hr	23	14	a	a	DT
cord-309582-ihrj84hr	23	15	great	great	JJ
cord-309582-ihrj84hr	23	16	number	number	NN
cord-309582-ihrj84hr	23	17	of	of	IN
cord-309582-ihrj84hr	23	18	deaths	death	NNS
cord-309582-ihrj84hr	23	19	.	.	.
cord-309582-ihrj84hr	24	1	Unfortunately	unfortunately	RB
cord-309582-ihrj84hr	24	2	,	,	,
cord-309582-ihrj84hr	24	3	till	till	IN
cord-309582-ihrj84hr	24	4	today	today	NN
cord-309582-ihrj84hr	24	5	there	there	EX
cord-309582-ihrj84hr	24	6	is	be	VBZ
cord-309582-ihrj84hr	24	7	no	no	DT
cord-309582-ihrj84hr	24	8	specific	specific	JJ
cord-309582-ihrj84hr	24	9	treatment	treatment	NN
cord-309582-ihrj84hr	24	10	or	or	CC
cord-309582-ihrj84hr	24	11	vaccination	vaccination	NN
cord-309582-ihrj84hr	24	12	for	for	IN
cord-309582-ihrj84hr	24	13	SARS	SARS	NNP
cord-309582-ihrj84hr	24	14	-	-	HYPH
cord-309582-ihrj84hr	24	15	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	24	16	.	.	.
cord-309582-ihrj84hr	25	1	Most	Most	JJS
cord-309582-ihrj84hr	25	2	of	of	IN
cord-309582-ihrj84hr	25	3	the	the	DT
cord-309582-ihrj84hr	25	4	suggested	suggest	VBN
cord-309582-ihrj84hr	25	5	treatment	treatment	NN
cord-309582-ihrj84hr	25	6	medications	medication	NNS
cord-309582-ihrj84hr	25	7	are	be	VBP
cord-309582-ihrj84hr	25	8	based	base	VBN
cord-309582-ihrj84hr	25	9	on	on	IN
cord-309582-ihrj84hr	25	10	in	in	IN
cord-309582-ihrj84hr	25	11	vitro	vitro	FW
cord-309582-ihrj84hr	25	12	laboratory	laboratory	NN
cord-309582-ihrj84hr	25	13	investigations	investigation	NNS
cord-309582-ihrj84hr	25	14	,	,	,
cord-309582-ihrj84hr	25	15	experimental	experimental	JJ
cord-309582-ihrj84hr	25	16	animal	animal	NN
cord-309582-ihrj84hr	25	17	models	model	NNS
cord-309582-ihrj84hr	25	18	,	,	,
cord-309582-ihrj84hr	25	19	or	or	CC
cord-309582-ihrj84hr	25	20	previous	previous	JJ
cord-309582-ihrj84hr	25	21	clinical	clinical	JJ
cord-309582-ihrj84hr	25	22	experience	experience	NN
cord-309582-ihrj84hr	25	23	in	in	IN
cord-309582-ihrj84hr	25	24	treating	treat	VBG
cord-309582-ihrj84hr	25	25	similar	similar	JJ
cord-309582-ihrj84hr	25	26	viruses	virus	NNS
cord-309582-ihrj84hr	25	27	such	such	JJ
cord-309582-ihrj84hr	25	28	as	as	IN
cord-309582-ihrj84hr	25	29	SARS	SARS	NNP
cord-309582-ihrj84hr	25	30	-	-	HYPH
cord-309582-ihrj84hr	25	31	CoV-1	CoV-1	NNP
cord-309582-ihrj84hr	25	32	or	or	CC
cord-309582-ihrj84hr	25	33	other	other	JJ
cord-309582-ihrj84hr	25	34	retroviral	retroviral	JJ
cord-309582-ihrj84hr	25	35	infections	infection	NNS
cord-309582-ihrj84hr	25	36	.	.	.
cord-309582-ihrj84hr	26	1	The	the	DT
cord-309582-ihrj84hr	26	2	running	running	NN
cord-309582-ihrj84hr	26	3	of	of	IN
cord-309582-ihrj84hr	26	4	any	any	DT
cord-309582-ihrj84hr	26	5	clinical	clinical	JJ
cord-309582-ihrj84hr	26	6	trial	trial	NN
cord-309582-ihrj84hr	26	7	during	during	IN
cord-309582-ihrj84hr	26	8	a	a	DT
cord-309582-ihrj84hr	26	9	pandemic	pandemic	NN
cord-309582-ihrj84hr	26	10	is	be	VBZ
cord-309582-ihrj84hr	26	11	affected	affect	VBN
cord-309582-ihrj84hr	26	12	at	at	IN
cord-309582-ihrj84hr	26	13	multiple	multiple	JJ
cord-309582-ihrj84hr	26	14	levels	level	NNS
cord-309582-ihrj84hr	26	15	.	.	.
cord-309582-ihrj84hr	27	1	Reasons	reason	NNS
cord-309582-ihrj84hr	27	2	for	for	IN
cord-309582-ihrj84hr	27	3	this	this	DT
cord-309582-ihrj84hr	27	4	include	include	VBP
cord-309582-ihrj84hr	27	5	patient	patient	JJ
cord-309582-ihrj84hr	27	6	hesitancy	hesitancy	NN
cord-309582-ihrj84hr	27	7	or	or	CC
cord-309582-ihrj84hr	27	8	inability	inability	NN
cord-309582-ihrj84hr	27	9	to	to	TO
cord-309582-ihrj84hr	27	10	continue	continue	VB
cord-309582-ihrj84hr	27	11	investigative	investigative	JJ
cord-309582-ihrj84hr	27	12	treatments	treatment	NNS
cord-309582-ihrj84hr	27	13	due	due	JJ
cord-309582-ihrj84hr	27	14	to	to	IN
cord-309582-ihrj84hr	27	15	self	self	NN
cord-309582-ihrj84hr	27	16	-	-	HYPH
cord-309582-ihrj84hr	27	17	isolation	isolation	NN
cord-309582-ihrj84hr	27	18	/	/	SYM
cord-309582-ihrj84hr	27	19	quarantine	quarantine	NN
cord-309582-ihrj84hr	27	20	,	,	,
cord-309582-ihrj84hr	27	21	or	or	CC
cord-309582-ihrj84hr	27	22	limited	limited	JJ
cord-309582-ihrj84hr	27	23	access	access	NN
cord-309582-ihrj84hr	27	24	to	to	IN
cord-309582-ihrj84hr	27	25	public	public	JJ
cord-309582-ihrj84hr	27	26	places	place	NNS
cord-309582-ihrj84hr	27	27	(	(	-LRB-
cord-309582-ihrj84hr	27	28	including	include	VBG
cord-309582-ihrj84hr	27	29	hospitals	hospital	NNS
cord-309582-ihrj84hr	27	30	)	)	-RRB-
cord-309582-ihrj84hr	27	31	.	.	.
cord-309582-ihrj84hr	28	1	Additional	additional	JJ
cord-309582-ihrj84hr	28	2	barriers	barrier	NNS
cord-309582-ihrj84hr	28	3	relate	relate	VBP
cord-309582-ihrj84hr	28	4	to	to	IN
cord-309582-ihrj84hr	28	5	health	health	NN
cord-309582-ihrj84hr	28	6	care	care	NN
cord-309582-ihrj84hr	28	7	professionals	professional	NNS
cord-309582-ihrj84hr	28	8	being	be	VBG
cord-309582-ihrj84hr	28	9	committed	commit	VBN
cord-309582-ihrj84hr	28	10	to	to	IN
cord-309582-ihrj84hr	28	11	other	other	JJ
cord-309582-ihrj84hr	28	12	critical	critical	JJ
cord-309582-ihrj84hr	28	13	tasks	task	NNS
cord-309582-ihrj84hr	28	14	or	or	CC
cord-309582-ihrj84hr	28	15	quarantining	quarantine	VBG
cord-309582-ihrj84hr	28	16	themselves	-PRON-	PRP
cord-309582-ihrj84hr	28	17	due	due	JJ
cord-309582-ihrj84hr	28	18	to	to	IN
cord-309582-ihrj84hr	28	19	contact	contact	NN
cord-309582-ihrj84hr	28	20	with	with	IN
cord-309582-ihrj84hr	28	21	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	28	22	positive	positive	JJ
cord-309582-ihrj84hr	28	23	patients	patient	NNS
cord-309582-ihrj84hr	28	24	.	.	.
cord-309582-ihrj84hr	29	1	The	the	DT
cord-309582-ihrj84hr	29	2	best	good	JJS
cord-309582-ihrj84hr	29	3	research	research	NN
cord-309582-ihrj84hr	29	4	approaches	approach	NNS
cord-309582-ihrj84hr	29	5	are	be	VBP
cord-309582-ihrj84hr	29	6	those	those	DT
cord-309582-ihrj84hr	29	7	that	that	WDT
cord-309582-ihrj84hr	29	8	adapt	adapt	VBP
cord-309582-ihrj84hr	29	9	to	to	IN
cord-309582-ihrj84hr	29	10	such	such	JJ
cord-309582-ihrj84hr	29	11	external	external	JJ
cord-309582-ihrj84hr	29	12	unplanned	unplanned	JJ
cord-309582-ihrj84hr	29	13	obstacles	obstacle	NNS
cord-309582-ihrj84hr	29	14	.	.	.
cord-309582-ihrj84hr	30	1	Ongoing	ongoing	JJ
cord-309582-ihrj84hr	30	2	clinical	clinical	JJ
cord-309582-ihrj84hr	30	3	trials	trial	NNS
cord-309582-ihrj84hr	30	4	before	before	IN
cord-309582-ihrj84hr	30	5	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	30	6	pandemic	pandemic	NN
cord-309582-ihrj84hr	30	7	have	have	VBP
cord-309582-ihrj84hr	30	8	the	the	DT
cord-309582-ihrj84hr	30	9	potential	potential	NN
cord-309582-ihrj84hr	30	10	for	for	IN
cord-309582-ihrj84hr	30	11	identifying	identify	VBG
cord-309582-ihrj84hr	30	12	important	important	JJ
cord-309582-ihrj84hr	30	13	therapies	therapy	NNS
cord-309582-ihrj84hr	30	14	in	in	IN
cord-309582-ihrj84hr	30	15	the	the	DT
cord-309582-ihrj84hr	30	16	long	long	JJ
cord-309582-ihrj84hr	30	17	-	-	HYPH
cord-309582-ihrj84hr	30	18	term	term	NN
cord-309582-ihrj84hr	30	19	if	if	IN
cord-309582-ihrj84hr	30	20	they	-PRON-	PRP
cord-309582-ihrj84hr	30	21	can	can	MD
cord-309582-ihrj84hr	30	22	be	be	VB
cord-309582-ihrj84hr	30	23	completed	complete	VBN
cord-309582-ihrj84hr	30	24	as	as	IN
cord-309582-ihrj84hr	30	25	planned	plan	VBN
cord-309582-ihrj84hr	30	26	.	.	.
cord-309582-ihrj84hr	31	1	However	however	RB
cord-309582-ihrj84hr	31	2	,	,	,
cord-309582-ihrj84hr	31	3	these	these	DT
cord-309582-ihrj84hr	31	4	clinical	clinical	JJ
cord-309582-ihrj84hr	31	5	trials	trial	NNS
cord-309582-ihrj84hr	31	6	may	may	MD
cord-309582-ihrj84hr	31	7	require	require	VB
cord-309582-ihrj84hr	31	8	modifications	modification	NNS
cord-309582-ihrj84hr	31	9	due	due	JJ
cord-309582-ihrj84hr	31	10	a	a	DT
cord-309582-ihrj84hr	31	11	pandemic	pandemic	NN
cord-309582-ihrj84hr	31	12	such	such	JJ
cord-309582-ihrj84hr	31	13	as	as	IN
cord-309582-ihrj84hr	31	14	this	this	DT
cord-309582-ihrj84hr	31	15	one	one	NN
cord-309582-ihrj84hr	31	16	to	to	TO
cord-309582-ihrj84hr	31	17	ensure	ensure	VB
cord-309582-ihrj84hr	31	18	the	the	DT
cord-309582-ihrj84hr	31	19	rights	right	NNS
cord-309582-ihrj84hr	31	20	,	,	,
cord-309582-ihrj84hr	31	21	safety	safety	NN
cord-309582-ihrj84hr	31	22	,	,	,
cord-309582-ihrj84hr	31	23	and	and	CC
cord-309582-ihrj84hr	31	24	wellbeing	wellbeing	NN
cord-309582-ihrj84hr	31	25	of	of	IN
cord-309582-ihrj84hr	31	26	participants	participant	NNS
cord-309582-ihrj84hr	31	27	as	as	RB
cord-309582-ihrj84hr	31	28	well	well	RB
cord-309582-ihrj84hr	31	29	as	as	IN
cord-309582-ihrj84hr	31	30	medical	medical	JJ
cord-309582-ihrj84hr	31	31	staff	staff	NN
cord-309582-ihrj84hr	31	32	involved	involve	VBN
cord-309582-ihrj84hr	31	33	in	in	IN
cord-309582-ihrj84hr	31	34	the	the	DT
cord-309582-ihrj84hr	31	35	conduction	conduction	NN
cord-309582-ihrj84hr	31	36	of	of	IN
cord-309582-ihrj84hr	31	37	clinical	clinical	JJ
cord-309582-ihrj84hr	31	38	trials	trial	NNS
cord-309582-ihrj84hr	31	39	.	.	.
cord-309582-ihrj84hr	32	1	Clinical	clinical	JJ
cord-309582-ihrj84hr	32	2	trials	trial	NNS
cord-309582-ihrj84hr	32	3	initiated	initiate	VBD
cord-309582-ihrj84hr	32	4	during	during	IN
cord-309582-ihrj84hr	32	5	the	the	DT
cord-309582-ihrj84hr	32	6	pandemic	pandemic	NN
cord-309582-ihrj84hr	32	7	must	must	MD
cord-309582-ihrj84hr	32	8	be	be	VB
cord-309582-ihrj84hr	32	9	time	time	NN
cord-309582-ihrj84hr	32	10	-	-	HYPH
cord-309582-ihrj84hr	32	11	efficient	efficient	JJ
cord-309582-ihrj84hr	32	12	and	and	CC
cord-309582-ihrj84hr	32	13	flexible	flexible	JJ
cord-309582-ihrj84hr	32	14	due	due	IN
cord-309582-ihrj84hr	32	15	to	to	IN
cord-309582-ihrj84hr	32	16	high	high	JJ
cord-309582-ihrj84hr	32	17	contagiousness	contagiousness	NN
cord-309582-ihrj84hr	32	18	of	of	IN
cord-309582-ihrj84hr	32	19	severe	severe	JJ
cord-309582-ihrj84hr	32	20	acute	acute	JJ
cord-309582-ihrj84hr	32	21	respiratory	respiratory	JJ
cord-309582-ihrj84hr	32	22	syndrome	syndrome	NN
cord-309582-ihrj84hr	32	23	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	32	24	2	2	CD
cord-309582-ihrj84hr	32	25	,	,	,
cord-309582-ihrj84hr	32	26	the	the	DT
cord-309582-ihrj84hr	32	27	significant	significant	JJ
cord-309582-ihrj84hr	32	28	number	number	NN
cord-309582-ihrj84hr	32	29	of	of	IN
cord-309582-ihrj84hr	32	30	reported	report	VBN
cord-309582-ihrj84hr	32	31	deaths	death	NNS
cord-309582-ihrj84hr	32	32	,	,	,
cord-309582-ihrj84hr	32	33	and	and	CC
cord-309582-ihrj84hr	32	34	time	time	NN
cord-309582-ihrj84hr	32	35	constraints	constraint	NNS
cord-309582-ihrj84hr	32	36	needed	need	VBN
cord-309582-ihrj84hr	32	37	to	to	TO
cord-309582-ihrj84hr	32	38	perform	perform	VB
cord-309582-ihrj84hr	32	39	high	high	JJ
cord-309582-ihrj84hr	32	40	quality	quality	NN
cord-309582-ihrj84hr	32	41	clinical	clinical	JJ
cord-309582-ihrj84hr	32	42	trials	trial	NNS
cord-309582-ihrj84hr	32	43	,	,	,
cord-309582-ihrj84hr	32	44	enrolling	enrol	VBG
cord-309582-ihrj84hr	32	45	adequate	adequate	JJ
cord-309582-ihrj84hr	32	46	sample	sample	NN
cord-309582-ihrj84hr	32	47	sizes	size	NNS
cord-309582-ihrj84hr	32	48	.	.	.
cord-309582-ihrj84hr	33	1	Collaboration	collaboration	NN
cord-309582-ihrj84hr	33	2	between	between	IN
cord-309582-ihrj84hr	33	3	different	different	JJ
cord-309582-ihrj84hr	33	4	countries	country	NNS
cord-309582-ihrj84hr	33	5	as	as	RB
cord-309582-ihrj84hr	33	6	well	well	RB
cord-309582-ihrj84hr	33	7	as	as	IN
cord-309582-ihrj84hr	33	8	implementation	implementation	NN
cord-309582-ihrj84hr	33	9	of	of	IN
cord-309582-ihrj84hr	33	10	innovative	innovative	JJ
cord-309582-ihrj84hr	33	11	clinical	clinical	JJ
cord-309582-ihrj84hr	33	12	trial	trial	NN
cord-309582-ihrj84hr	33	13	designs	design	NNS
cord-309582-ihrj84hr	33	14	are	be	VBP
cord-309582-ihrj84hr	33	15	essential	essential	JJ
cord-309582-ihrj84hr	33	16	to	to	TO
cord-309582-ihrj84hr	33	17	successfully	successfully	RB
cord-309582-ihrj84hr	33	18	complete	complete	VB
cord-309582-ihrj84hr	33	19	such	such	JJ
cord-309582-ihrj84hr	33	20	initiatives	initiative	NNS
cord-309582-ihrj84hr	33	21	during	during	IN
cord-309582-ihrj84hr	33	22	the	the	DT
cord-309582-ihrj84hr	33	23	current	current	JJ
cord-309582-ihrj84hr	33	24	pandemic	pandemic	NN
cord-309582-ihrj84hr	33	25	.	.	.
cord-309582-ihrj84hr	34	1	Studies	study	NNS
cord-309582-ihrj84hr	34	2	looking	look	VBG
cord-309582-ihrj84hr	34	3	at	at	IN
cord-309582-ihrj84hr	34	4	the	the	DT
cord-309582-ihrj84hr	34	5	long	long	JJ
cord-309582-ihrj84hr	34	6	The	the	DT
cord-309582-ihrj84hr	34	7	number	number	NN
cord-309582-ihrj84hr	34	8	of	of	IN
cord-309582-ihrj84hr	34	9	infectious	infectious	JJ
cord-309582-ihrj84hr	34	10	diseases	disease	NNS
cord-309582-ihrj84hr	34	11	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	34	12	over	over	IN
cord-309582-ihrj84hr	34	13	the	the	DT
cord-309582-ihrj84hr	34	14	past	past	JJ
cord-309582-ihrj84hr	34	15	few	few	JJ
cord-309582-ihrj84hr	34	16	decades	decade	NNS
cord-309582-ihrj84hr	34	17	have	have	VBP
cord-309582-ihrj84hr	34	18	increased	increase	VBN
cord-309582-ihrj84hr	34	19	.	.	.
cord-309582-ihrj84hr	35	1	This	this	DT
cord-309582-ihrj84hr	35	2	has	have	VBZ
cord-309582-ihrj84hr	35	3	created	create	VBN
cord-309582-ihrj84hr	35	4	an	an	DT
cord-309582-ihrj84hr	35	5	enormous	enormous	JJ
cord-309582-ihrj84hr	35	6	additional	additional	JJ
cord-309582-ihrj84hr	35	7	burden	burden	NN
cord-309582-ihrj84hr	35	8	on	on	IN
cord-309582-ihrj84hr	35	9	the	the	DT
cord-309582-ihrj84hr	35	10	health	health	NN
cord-309582-ihrj84hr	35	11	systems	system	NNS
cord-309582-ihrj84hr	35	12	of	of	IN
cord-309582-ihrj84hr	35	13	many	many	JJ
cord-309582-ihrj84hr	35	14	countries	country	NNS
cord-309582-ihrj84hr	35	15	around	around	IN
cord-309582-ihrj84hr	35	16	the	the	DT
cord-309582-ihrj84hr	35	17	world	world	NN
cord-309582-ihrj84hr	35	18	.	.	.
cord-309582-ihrj84hr	36	1	As	as	IN
cord-309582-ihrj84hr	36	2	a	a	DT
cord-309582-ihrj84hr	36	3	majority	majority	NN
cord-309582-ihrj84hr	36	4	of	of	IN
cord-309582-ihrj84hr	36	5	research	research	NN
cord-309582-ihrj84hr	36	6	activities	activity	NNS
cord-309582-ihrj84hr	36	7	during	during	IN
cord-309582-ihrj84hr	36	8	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	36	9	targeting	target	VBG
cord-309582-ihrj84hr	36	10	the	the	DT
cord-309582-ihrj84hr	36	11	causal	causal	JJ
cord-309582-ihrj84hr	36	12	organism	organism	NN
cord-309582-ihrj84hr	36	13	must	must	MD
cord-309582-ihrj84hr	36	14	be	be	VB
cord-309582-ihrj84hr	36	15	completed	complete	VBN
cord-309582-ihrj84hr	36	16	in	in	IN
cord-309582-ihrj84hr	36	17	a	a	DT
cord-309582-ihrj84hr	36	18	timely	timely	JJ
cord-309582-ihrj84hr	36	19	fashion	fashion	NN
cord-309582-ihrj84hr	36	20	,	,	,
cord-309582-ihrj84hr	36	21	it	-PRON-	PRP
cord-309582-ihrj84hr	36	22	is	be	VBZ
cord-309582-ihrj84hr	36	23	of	of	IN
cord-309582-ihrj84hr	36	24	no	no	DT
cord-309582-ihrj84hr	36	25	surprise	surprise	NN
cord-309582-ihrj84hr	36	26	that	that	IN
cord-309582-ihrj84hr	36	27	effective	effective	JJ
cord-309582-ihrj84hr	36	28	preventative	preventative	JJ
cord-309582-ihrj84hr	36	29	measures	measure	NNS
cord-309582-ihrj84hr	36	30	such	such	JJ
cord-309582-ihrj84hr	36	31	as	as	IN
cord-309582-ihrj84hr	36	32	vaccination	vaccination	NN
cord-309582-ihrj84hr	36	33	or	or	CC
cord-309582-ihrj84hr	36	34	therapies	therapy	NNS
cord-309582-ihrj84hr	36	35	have	have	VBP
cord-309582-ihrj84hr	36	36	not	not	RB
cord-309582-ihrj84hr	36	37	been	be	VBN
cord-309582-ihrj84hr	36	38	available	available	JJ
cord-309582-ihrj84hr	36	39	for	for	IN
cord-309582-ihrj84hr	36	40	many	many	JJ
cord-309582-ihrj84hr	36	41	previous	previous	JJ
cord-309582-ihrj84hr	36	42	pandemic	pandemic	NN
cord-309582-ihrj84hr	36	43	infectious	infectious	JJ
cord-309582-ihrj84hr	36	44	diseases	disease	NNS
cord-309582-ihrj84hr	36	45	;	;	:
cord-309582-ihrj84hr	36	46	in	in	IN
cord-309582-ihrj84hr	36	47	fact	fact	NN
cord-309582-ihrj84hr	36	48	most	most	JJS
cord-309582-ihrj84hr	36	49	of	of	IN
cord-309582-ihrj84hr	36	50	the	the	DT
cord-309582-ihrj84hr	36	51	previously	previously	RB
cord-309582-ihrj84hr	36	52	used	use	VBN
cord-309582-ihrj84hr	36	53	medications	medication	NNS
cord-309582-ihrj84hr	36	54	during	during	IN
cord-309582-ihrj84hr	36	55	past	past	JJ
cord-309582-ihrj84hr	36	56	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	36	57	have	have	VBP
cord-309582-ihrj84hr	36	58	not	not	RB
cord-309582-ihrj84hr	36	59	been	be	VBN
cord-309582-ihrj84hr	36	60	based	base	VBN
cord-309582-ihrj84hr	36	61	on	on	IN
cord-309582-ihrj84hr	36	62	high	high	JJ
cord-309582-ihrj84hr	36	63	quality	quality	NN
cord-309582-ihrj84hr	36	64	evidence	evidence	NN
cord-309582-ihrj84hr	36	65	[	[	-LRB-
cord-309582-ihrj84hr	36	66	1	1	CD
cord-309582-ihrj84hr	36	67	]	]	-RRB-
cord-309582-ihrj84hr	36	68	.	.	.
cord-309582-ihrj84hr	37	1	Despite	despite	IN
cord-309582-ihrj84hr	37	2	the	the	DT
cord-309582-ihrj84hr	37	3	dedication	dedication	NN
cord-309582-ihrj84hr	37	4	of	of	IN
cord-309582-ihrj84hr	37	5	enormous	enormous	JJ
cord-309582-ihrj84hr	37	6	resources	resource	NNS
cord-309582-ihrj84hr	37	7	,	,	,
cord-309582-ihrj84hr	37	8	the	the	DT
cord-309582-ihrj84hr	37	9	advancement	advancement	NN
cord-309582-ihrj84hr	37	10	in	in	IN
cord-309582-ihrj84hr	37	11	health	health	NN
cord-309582-ihrj84hr	37	12	care	care	NN
cord-309582-ihrj84hr	37	13	systems	system	NNS
cord-309582-ihrj84hr	37	14	and	and	CC
cord-309582-ihrj84hr	37	15	collaboration	collaboration	NN
cord-309582-ihrj84hr	37	16	between	between	IN
cord-309582-ihrj84hr	37	17	different	different	JJ
cord-309582-ihrj84hr	37	18	investigators	investigator	NNS
cord-309582-ihrj84hr	37	19	across	across	IN
cord-309582-ihrj84hr	37	20	the	the	DT
cord-309582-ihrj84hr	37	21	world	world	NN
cord-309582-ihrj84hr	37	22	,	,	,
cord-309582-ihrj84hr	37	23	only	only	RB
cord-309582-ihrj84hr	37	24	a	a	DT
cord-309582-ihrj84hr	37	25	small	small	JJ
cord-309582-ihrj84hr	37	26	number	number	NN
cord-309582-ihrj84hr	37	27	of	of	IN
cord-309582-ihrj84hr	37	28	patients	patient	NNS
cord-309582-ihrj84hr	37	29	over	over	IN
cord-309582-ihrj84hr	37	30	the	the	DT
cord-309582-ihrj84hr	37	31	last	last	JJ
cord-309582-ihrj84hr	37	32	decade	decade	NN
cord-309582-ihrj84hr	37	33	have	have	VBP
cord-309582-ihrj84hr	37	34	in	in	IN
cord-309582-ihrj84hr	37	35	fact	fact	NN
cord-309582-ihrj84hr	37	36	benefited	benefit	VBN
cord-309582-ihrj84hr	37	37	from	from	IN
cord-309582-ihrj84hr	37	38	clinical	clinical	JJ
cord-309582-ihrj84hr	37	39	research	research	NN
cord-309582-ihrj84hr	37	40	performed	perform	VBN
cord-309582-ihrj84hr	37	41	during	during	IN
cord-309582-ihrj84hr	37	42	different	different	JJ
cord-309582-ihrj84hr	37	43	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	37	44	of	of	IN
cord-309582-ihrj84hr	37	45	respiratory	respiratory	JJ
cord-309582-ihrj84hr	37	46	viruses	virus	NNS
cord-309582-ihrj84hr	37	47	such	such	JJ
cord-309582-ihrj84hr	37	48	as	as	IN
cord-309582-ihrj84hr	37	49	was	be	VBD
cord-309582-ihrj84hr	37	50	the	the	DT
cord-309582-ihrj84hr	37	51	case	case	NN
cord-309582-ihrj84hr	37	52	for	for	IN
cord-309582-ihrj84hr	37	53	the	the	DT
cord-309582-ihrj84hr	37	54	severe	severe	JJ
cord-309582-ihrj84hr	37	55	acute	acute	JJ
cord-309582-ihrj84hr	37	56	respiratory	respiratory	JJ
cord-309582-ihrj84hr	37	57	syndrome	syndrome	NN
cord-309582-ihrj84hr	37	58	(	(	-LRB-
cord-309582-ihrj84hr	37	59	SARS	SARS	NNP
cord-309582-ihrj84hr	37	60	)	)	-RRB-
cord-309582-ihrj84hr	37	61	,	,	,
cord-309582-ihrj84hr	37	62	the	the	DT
cord-309582-ihrj84hr	37	63	HIN1	HIN1	NNPS
cord-309582-ihrj84hr	37	64	flu	flu	NN
cord-309582-ihrj84hr	37	65	virus	virus	NN
cord-309582-ihrj84hr	37	66	(	(	-LRB-
cord-309582-ihrj84hr	37	67	swine	swine	NNP
cord-309582-ihrj84hr	37	68	flu	flu	NN
cord-309582-ihrj84hr	37	69	)	)	-RRB-
cord-309582-ihrj84hr	37	70	or	or	CC
cord-309582-ihrj84hr	37	71	the	the	DT
cord-309582-ihrj84hr	37	72	Middle	Middle	NNP
cord-309582-ihrj84hr	37	73	East	East	NNP
cord-309582-ihrj84hr	37	74	Respiratory	Respiratory	NNP
cord-309582-ihrj84hr	37	75	Syndrome	Syndrome	NNP
cord-309582-ihrj84hr	37	76	.	.	.
cord-309582-ihrj84hr	38	1	Most	Most	JJS
cord-309582-ihrj84hr	38	2	of	of	IN
cord-309582-ihrj84hr	38	3	the	the	DT
cord-309582-ihrj84hr	38	4	medical	medical	JJ
cord-309582-ihrj84hr	38	5	research	research	NN
cord-309582-ihrj84hr	38	6	allocated	allocate	VBD
cord-309582-ihrj84hr	38	7	resources	resource	NNS
cord-309582-ihrj84hr	38	8	and	and	CC
cord-309582-ihrj84hr	38	9	funding	funding	NN
cord-309582-ihrj84hr	38	10	tend	tend	VBP
cord-309582-ihrj84hr	38	11	to	to	TO
cord-309582-ihrj84hr	38	12	happen	happen	VB
cord-309582-ihrj84hr	38	13	during	during	IN
cord-309582-ihrj84hr	38	14	the	the	DT
cord-309582-ihrj84hr	38	15	disease	disease	NN
cord-309582-ihrj84hr	38	16	outbreak	outbreak	NN
cord-309582-ihrj84hr	38	17	.	.	.
cord-309582-ihrj84hr	39	1	Unfortunately	unfortunately	RB
cord-309582-ihrj84hr	39	2	lack	lack	NN
cord-309582-ihrj84hr	39	3	of	of	IN
cord-309582-ihrj84hr	39	4	continuation	continuation	NN
cord-309582-ihrj84hr	39	5	of	of	IN
cord-309582-ihrj84hr	39	6	funding	funding	NN
cord-309582-ihrj84hr	39	7	once	once	IN
cord-309582-ihrj84hr	39	8	the	the	DT
cord-309582-ihrj84hr	39	9	outbreak	outbreak	NN
cord-309582-ihrj84hr	39	10	is	be	VBZ
cord-309582-ihrj84hr	39	11	over	over	RB
cord-309582-ihrj84hr	39	12	has	have	VBZ
cord-309582-ihrj84hr	39	13	led	lead	VBN
cord-309582-ihrj84hr	39	14	to	to	IN
cord-309582-ihrj84hr	39	15	disruption	disruption	NN
cord-309582-ihrj84hr	39	16	of	of	IN
cord-309582-ihrj84hr	39	17	many	many	JJ
cord-309582-ihrj84hr	39	18	clinical	clinical	JJ
cord-309582-ihrj84hr	39	19	trials	trial	NNS
cord-309582-ihrj84hr	39	20	assessing	assess	VBG
cord-309582-ihrj84hr	39	21	preventative	preventative	JJ
cord-309582-ihrj84hr	39	22	,	,	,
cord-309582-ihrj84hr	39	23	diagnostic	diagnostic	JJ
cord-309582-ihrj84hr	39	24	,	,	,
cord-309582-ihrj84hr	39	25	and	and	CC
cord-309582-ihrj84hr	39	26	therapeutic	therapeutic	JJ
cord-309582-ihrj84hr	39	27	strategies	strategy	NNS
cord-309582-ihrj84hr	39	28	[	[	-LRB-
cord-309582-ihrj84hr	39	29	2	2	CD
cord-309582-ihrj84hr	39	30	]	]	-RRB-
cord-309582-ihrj84hr	39	31	.	.	.
cord-309582-ihrj84hr	40	1	The	the	DT
cord-309582-ihrj84hr	40	2	current	current	JJ
cord-309582-ihrj84hr	40	3	pandemic	pandemic	NN
cord-309582-ihrj84hr	40	4	of	of	IN
cord-309582-ihrj84hr	40	5	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	40	6	disease	disease	NN
cord-309582-ihrj84hr	40	7	2019	2019	CD
cord-309582-ihrj84hr	40	8	(	(	-LRB-
cord-309582-ihrj84hr	40	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	40	10	)	)	-RRB-
cord-309582-ihrj84hr	40	11	which	which	WDT
cord-309582-ihrj84hr	40	12	was	be	VBD
cord-309582-ihrj84hr	40	13	first	first	RB
cord-309582-ihrj84hr	40	14	detected	detect	VBN
cord-309582-ihrj84hr	40	15	in	in	IN
cord-309582-ihrj84hr	40	16	Wuhan	Wuhan	NNP
cord-309582-ihrj84hr	40	17	,	,	,
cord-309582-ihrj84hr	40	18	China	China	NNP
cord-309582-ihrj84hr	40	19	in	in	IN
cord-309582-ihrj84hr	40	20	December	December	NNP
cord-309582-ihrj84hr	40	21	2019	2019	CD
cord-309582-ihrj84hr	40	22	is	be	VBZ
cord-309582-ihrj84hr	40	23	caused	cause	VBN
cord-309582-ihrj84hr	40	24	by	by	IN
cord-309582-ihrj84hr	40	25	the	the	DT
cord-309582-ihrj84hr	40	26	novel	novel	JJ
cord-309582-ihrj84hr	40	27	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	40	28	named	name	VBN
cord-309582-ihrj84hr	40	29	severe	severe	JJ
cord-309582-ihrj84hr	40	30	acute	acute	JJ
cord-309582-ihrj84hr	40	31	respiratory	respiratory	JJ
cord-309582-ihrj84hr	40	32	syndrome	syndrome	NN
cord-309582-ihrj84hr	40	33	coronavirus-2	coronavirus-2	NNP
cord-309582-ihrj84hr	40	34	(	(	-LRB-
cord-309582-ihrj84hr	40	35	SARS	SARS	NNP
cord-309582-ihrj84hr	40	36	-	-	HYPH
cord-309582-ihrj84hr	40	37	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	40	38	)	)	-RRB-
cord-309582-ihrj84hr	40	39	[	[	-LRB-
cord-309582-ihrj84hr	40	40	3	3	CD
cord-309582-ihrj84hr	40	41	]	]	-RRB-
cord-309582-ihrj84hr	40	42	.	.	.
cord-309582-ihrj84hr	41	1	The	the	DT
cord-309582-ihrj84hr	41	2	virus	virus	NN
cord-309582-ihrj84hr	41	3	eventually	eventually	RB
cord-309582-ihrj84hr	41	4	spread	spread	VBD
cord-309582-ihrj84hr	41	5	to	to	IN
cord-309582-ihrj84hr	41	6	different	different	JJ
cord-309582-ihrj84hr	41	7	regions	region	NNS
cord-309582-ihrj84hr	41	8	of	of	IN
cord-309582-ihrj84hr	41	9	China	China	NNP
cord-309582-ihrj84hr	41	10	and	and	CC
cord-309582-ihrj84hr	41	11	to	to	IN
cord-309582-ihrj84hr	41	12	the	the	DT
cord-309582-ihrj84hr	41	13	rest	rest	NN
cord-309582-ihrj84hr	41	14	of	of	IN
cord-309582-ihrj84hr	41	15	the	the	DT
cord-309582-ihrj84hr	41	16	world	world	NN
cord-309582-ihrj84hr	41	17	leading	lead	VBG
cord-309582-ihrj84hr	41	18	to	to	IN
cord-309582-ihrj84hr	41	19	more	more	JJR
cord-309582-ihrj84hr	41	20	than	than	IN
cord-309582-ihrj84hr	41	21	three	three	CD
cord-309582-ihrj84hr	41	22	million	million	CD
cord-309582-ihrj84hr	41	23	confirmed	confirm	VBN
cord-309582-ihrj84hr	41	24	cases	case	NNS
cord-309582-ihrj84hr	41	25	and	and	CC
cord-309582-ihrj84hr	41	26	hundreds	hundred	NNS
cord-309582-ihrj84hr	41	27	of	of	IN
cord-309582-ihrj84hr	41	28	thousands	thousand	NNS
cord-309582-ihrj84hr	41	29	of	of	IN
cord-309582-ihrj84hr	41	30	deaths	death	NNS
cord-309582-ihrj84hr	41	31	at	at	IN
cord-309582-ihrj84hr	41	32	the	the	DT
cord-309582-ihrj84hr	41	33	time	time	NN
cord-309582-ihrj84hr	41	34	of	of	IN
cord-309582-ihrj84hr	41	35	writing	writing	NN
cord-309582-ihrj84hr	41	36	of	of	IN
cord-309582-ihrj84hr	41	37	this	this	DT
cord-309582-ihrj84hr	41	38	manuscript	manuscript	NN
cord-309582-ihrj84hr	41	39	[	[	-LRB-
cord-309582-ihrj84hr	41	40	4	4	CD
cord-309582-ihrj84hr	41	41	]	]	-RRB-
cord-309582-ihrj84hr	41	42	.	.	.
cord-309582-ihrj84hr	42	1	Initial	initial	JJ
cord-309582-ihrj84hr	42	2	reports	report	NNS
cord-309582-ihrj84hr	42	3	from	from	IN
cord-309582-ihrj84hr	42	4	the	the	DT
cord-309582-ihrj84hr	42	5	highly	highly	RB
cord-309582-ihrj84hr	42	6	affected	affect	VBN
cord-309582-ihrj84hr	42	7	three	three	CD
cord-309582-ihrj84hr	42	8	countries	country	NNS
cord-309582-ihrj84hr	42	9	China	China	NNP
cord-309582-ihrj84hr	42	10	,	,	,
cord-309582-ihrj84hr	42	11	Italy	Italy	NNP
cord-309582-ihrj84hr	42	12	and	and	CC
cord-309582-ihrj84hr	42	13	Spain	Spain	NNP
cord-309582-ihrj84hr	42	14	suggest	suggest	VBP
cord-309582-ihrj84hr	42	15	that	that	IN
cord-309582-ihrj84hr	42	16	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	42	17	has	have	VBZ
cord-309582-ihrj84hr	42	18	caused	cause	VBN
cord-309582-ihrj84hr	42	19	high	high	JJ
cord-309582-ihrj84hr	42	20	mortality	mortality	NN
cord-309582-ihrj84hr	42	21	rate	rate	NN
cord-309582-ihrj84hr	42	22	and/or	and/or	CC
cord-309582-ihrj84hr	42	23	overwhelmed	overwhelmed	JJ
cord-309582-ihrj84hr	42	24	regional	regional	JJ
cord-309582-ihrj84hr	42	25	intensive	intensive	JJ
cord-309582-ihrj84hr	42	26	care	care	NN
cord-309582-ihrj84hr	42	27	units	unit	NNS
cord-309582-ihrj84hr	42	28	(	(	-LRB-
cord-309582-ihrj84hr	42	29	ICU	ICU	NNP
cord-309582-ihrj84hr	42	30	)	)	-RRB-
cord-309582-ihrj84hr	42	31	capacity	capacity	NN
cord-309582-ihrj84hr	42	32	[	[	-LRB-
cord-309582-ihrj84hr	42	33	5	5	CD
cord-309582-ihrj84hr	42	34	,	,	,
cord-309582-ihrj84hr	42	35	6	6	CD
cord-309582-ihrj84hr	42	36	]	]	-RRB-
cord-309582-ihrj84hr	42	37	.	.	.
cord-309582-ihrj84hr	43	1	The	the	DT
cord-309582-ihrj84hr	43	2	virus	virus	NN
cord-309582-ihrj84hr	43	3	spreads	spread	VBZ
cord-309582-ihrj84hr	43	4	via	via	IN
cord-309582-ihrj84hr	43	5	contact	contact	NN
cord-309582-ihrj84hr	43	6	with	with	IN
cord-309582-ihrj84hr	43	7	infected	infected	JJ
cord-309582-ihrj84hr	43	8	upper	upper	JJ
cord-309582-ihrj84hr	43	9	respiratory	respiratory	JJ
cord-309582-ihrj84hr	43	10	droplets	droplet	NNS
cord-309582-ihrj84hr	43	11	.	.	.
cord-309582-ihrj84hr	44	1	The	the	DT
cord-309582-ihrj84hr	44	2	clinical	clinical	JJ
cord-309582-ihrj84hr	44	3	presentation	presentation	NN
cord-309582-ihrj84hr	44	4	varies	vary	VBZ
cord-309582-ihrj84hr	44	5	markedly	markedly	RB
cord-309582-ihrj84hr	44	6	from	from	IN
cord-309582-ihrj84hr	44	7	asymptomatic	asymptomatic	JJ
cord-309582-ihrj84hr	44	8	carriers	carrier	NNS
cord-309582-ihrj84hr	44	9	to	to	IN
cord-309582-ihrj84hr	44	10	patients	patient	NNS
cord-309582-ihrj84hr	44	11	with	with	IN
cord-309582-ihrj84hr	44	12	acute	acute	JJ
cord-309582-ihrj84hr	44	13	respiratory	respiratory	JJ
cord-309582-ihrj84hr	44	14	distress	distress	NN
cord-309582-ihrj84hr	44	15	syndrome	syndrome	NN
cord-309582-ihrj84hr	44	16	requiring	require	VBG
cord-309582-ihrj84hr	44	17	ICU	ICU	NNP
cord-309582-ihrj84hr	44	18	admission	admission	NN
cord-309582-ihrj84hr	44	19	and	and	CC
cord-309582-ihrj84hr	44	20	mechanical	mechanical	JJ
cord-309582-ihrj84hr	44	21	ventilation	ventilation	NN
cord-309582-ihrj84hr	44	22	[	[	-LRB-
cord-309582-ihrj84hr	44	23	7	7	CD
cord-309582-ihrj84hr	44	24	]	]	-RRB-
cord-309582-ihrj84hr	44	25	.	.	.
cord-309582-ihrj84hr	45	1	Certain	certain	JJ
cord-309582-ihrj84hr	45	2	groups	group	NNS
cord-309582-ihrj84hr	45	3	of	of	IN
cord-309582-ihrj84hr	45	4	patients	patient	NNS
cord-309582-ihrj84hr	45	5	are	be	VBP
cord-309582-ihrj84hr	45	6	at	at	IN
cord-309582-ihrj84hr	45	7	higher	high	JJR
cord-309582-ihrj84hr	45	8	risk	risk	NN
cord-309582-ihrj84hr	45	9	for	for	IN
cord-309582-ihrj84hr	45	10	developing	develop	VBG
cord-309582-ihrj84hr	45	11	complications	complication	NNS
cord-309582-ihrj84hr	45	12	and	and	CC
cord-309582-ihrj84hr	45	13	death	death	NN
cord-309582-ihrj84hr	45	14	.	.	.
cord-309582-ihrj84hr	46	1	High	high	JJ
cord-309582-ihrj84hr	46	2	mortality	mortality	NN
cord-309582-ihrj84hr	46	3	rates	rate	NNS
cord-309582-ihrj84hr	46	4	have	have	VBP
cord-309582-ihrj84hr	46	5	been	be	VBN
cord-309582-ihrj84hr	46	6	associated	associate	VBN
cord-309582-ihrj84hr	46	7	with	with	IN
cord-309582-ihrj84hr	46	8	advanced	advanced	JJ
cord-309582-ihrj84hr	46	9	age	age	NN
cord-309582-ihrj84hr	46	10	,	,	,
cord-309582-ihrj84hr	46	11	presence	presence	NN
cord-309582-ihrj84hr	46	12	of	of	IN
cord-309582-ihrj84hr	46	13	underlying	underlie	VBG
cord-309582-ihrj84hr	46	14	disease	disease	NN
cord-309582-ihrj84hr	46	15	,	,	,
cord-309582-ihrj84hr	46	16	presence	presence	NN
cord-309582-ihrj84hr	46	17	of	of	IN
cord-309582-ihrj84hr	46	18	secondary	secondary	JJ
cord-309582-ihrj84hr	46	19	infection	infection	NN
cord-309582-ihrj84hr	46	20	and	and	CC
cord-309582-ihrj84hr	46	21	elevated	elevate	VBN
cord-309582-ihrj84hr	46	22	inflammatory	inflammatory	JJ
cord-309582-ihrj84hr	46	23	markers	marker	NNS
cord-309582-ihrj84hr	46	24	[	[	-LRB-
cord-309582-ihrj84hr	46	25	8	8	CD
cord-309582-ihrj84hr	46	26	]	]	-RRB-
cord-309582-ihrj84hr	46	27	.	.	.
cord-309582-ihrj84hr	47	1	Medical	medical	JJ
cord-309582-ihrj84hr	47	2	personnel	personnel	NNS
cord-309582-ihrj84hr	47	3	in	in	IN
cord-309582-ihrj84hr	47	4	many	many	JJ
cord-309582-ihrj84hr	47	5	countries	country	NNS
cord-309582-ihrj84hr	47	6	have	have	VBP
cord-309582-ihrj84hr	47	7	also	also	RB
cord-309582-ihrj84hr	47	8	been	be	VBN
cord-309582-ihrj84hr	47	9	affected	affect	VBN
cord-309582-ihrj84hr	47	10	,	,	,
cord-309582-ihrj84hr	47	11	leading	lead	VBG
cord-309582-ihrj84hr	47	12	to	to	IN
cord-309582-ihrj84hr	47	13	absence	absence	NN
cord-309582-ihrj84hr	47	14	from	from	IN
cord-309582-ihrj84hr	47	15	work	work	NN
cord-309582-ihrj84hr	47	16	and	and	CC
cord-309582-ihrj84hr	47	17	,	,	,
cord-309582-ihrj84hr	47	18	tragically	tragically	RB
cord-309582-ihrj84hr	47	19	,	,	,
cord-309582-ihrj84hr	47	20	death	death	NN
cord-309582-ihrj84hr	47	21	in	in	IN
cord-309582-ihrj84hr	47	22	some	some	DT
cord-309582-ihrj84hr	47	23	cases	case	NNS
cord-309582-ihrj84hr	47	24	.	.	.
cord-309582-ihrj84hr	48	1	Unfortunately	unfortunately	RB
cord-309582-ihrj84hr	48	2	,	,	,
cord-309582-ihrj84hr	48	3	till	till	IN
cord-309582-ihrj84hr	48	4	today	today	NN
cord-309582-ihrj84hr	48	5	there	there	EX
cord-309582-ihrj84hr	48	6	is	be	VBZ
cord-309582-ihrj84hr	48	7	no	no	DT
cord-309582-ihrj84hr	48	8	specific	specific	JJ
cord-309582-ihrj84hr	48	9	treatment	treatment	NN
cord-309582-ihrj84hr	48	10	or	or	CC
cord-309582-ihrj84hr	48	11	vaccination	vaccination	NN
cord-309582-ihrj84hr	48	12	for	for	IN
cord-309582-ihrj84hr	48	13	SARS	SARS	NNP
cord-309582-ihrj84hr	48	14	-	-	HYPH
cord-309582-ihrj84hr	48	15	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	48	16	Reports	Reports	NNPS
cord-309582-ihrj84hr	48	17	from	from	IN
cord-309582-ihrj84hr	48	18	initially	initially	RB
cord-309582-ihrj84hr	48	19	affected	affect	VBN
cord-309582-ihrj84hr	48	20	countries	country	NNS
cord-309582-ihrj84hr	48	21	describe	describe	VBP
cord-309582-ihrj84hr	48	22	using	use	VBG
cord-309582-ihrj84hr	48	23	different	different	JJ
cord-309582-ihrj84hr	48	24	medications	medication	NNS
cord-309582-ihrj84hr	48	25	such	such	JJ
cord-309582-ihrj84hr	48	26	as	as	IN
cord-309582-ihrj84hr	48	27	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-309582-ihrj84hr	48	28	with	with	IN
cord-309582-ihrj84hr	48	29	Azithromycin	Azithromycin	NNP
cord-309582-ihrj84hr	48	30	and	and	CC
cord-309582-ihrj84hr	48	31	in	in	IN
cord-309582-ihrj84hr	48	32	some	some	DT
cord-309582-ihrj84hr	48	33	adding	add	VBG
cord-309582-ihrj84hr	48	34	anti	anti	JJ
cord-309582-ihrj84hr	48	35	-	-	JJ
cord-309582-ihrj84hr	48	36	viral	viral	JJ
cord-309582-ihrj84hr	48	37	medications	medication	NNS
cord-309582-ihrj84hr	48	38	such	such	JJ
cord-309582-ihrj84hr	48	39	as	as	IN
cord-309582-ihrj84hr	48	40	Lopinavir	Lopinavir	NNP
cord-309582-ihrj84hr	48	41	/	/	SYM
cord-309582-ihrj84hr	48	42	Ritonavir	Ritonavir	NNP
cord-309582-ihrj84hr	48	43	,	,	,
cord-309582-ihrj84hr	48	44	Remdesivir	Remdesivir	NNP
cord-309582-ihrj84hr	48	45	or	or	CC
cord-309582-ihrj84hr	48	46	Favipiravir	Favipiravir	NNP
cord-309582-ihrj84hr	48	47	for	for	IN
cord-309582-ihrj84hr	48	48	severe	severe	JJ
cord-309582-ihrj84hr	48	49	cases	case	NNS
cord-309582-ihrj84hr	48	50	[	[	-LRB-
cord-309582-ihrj84hr	48	51	9	9	CD
cord-309582-ihrj84hr	48	52	]	]	-RRB-
cord-309582-ihrj84hr	48	53	[	[	-LRB-
cord-309582-ihrj84hr	48	54	10	10	CD
cord-309582-ihrj84hr	48	55	]	]	-RRB-
cord-309582-ihrj84hr	48	56	[	[	-LRB-
cord-309582-ihrj84hr	48	57	11	11	CD
cord-309582-ihrj84hr	48	58	]	]	-RRB-
cord-309582-ihrj84hr	48	59	[	[	-LRB-
cord-309582-ihrj84hr	48	60	12	12	CD
cord-309582-ihrj84hr	48	61	]	]	-RRB-
cord-309582-ihrj84hr	48	62	[	[	-LRB-
cord-309582-ihrj84hr	48	63	13	13	CD
cord-309582-ihrj84hr	48	64	]	]	-RRB-
cord-309582-ihrj84hr	48	65	.	.	.
cord-309582-ihrj84hr	49	1	Other	other	JJ
cord-309582-ihrj84hr	49	2	management	management	NN
cord-309582-ihrj84hr	49	3	options	option	NNS
cord-309582-ihrj84hr	49	4	include	include	VBP
cord-309582-ihrj84hr	49	5	Inter	Inter	NNP
cord-309582-ihrj84hr	49	6	-	-	HYPH
cord-309582-ihrj84hr	49	7	Leukin	Leukin	NNP
cord-309582-ihrj84hr	49	8	6	6	CD
cord-309582-ihrj84hr	49	9	and	and	CC
cord-309582-ihrj84hr	49	10	extracted	extract	VBN
cord-309582-ihrj84hr	49	11	immunoglobulin	immunoglobulin	NN
cord-309582-ihrj84hr	49	12	from	from	IN
cord-309582-ihrj84hr	49	13	recovered	recovered	JJ
cord-309582-ihrj84hr	49	14	patients	patient	NNS
cord-309582-ihrj84hr	49	15	that	that	WDT
cord-309582-ihrj84hr	49	16	have	have	VBP
cord-309582-ihrj84hr	49	17	also	also	RB
cord-309582-ihrj84hr	49	18	been	be	VBN
cord-309582-ihrj84hr	49	19	used	use	VBN
cord-309582-ihrj84hr	49	20	with	with	IN
cord-309582-ihrj84hr	49	21	variable	variable	JJ
cord-309582-ihrj84hr	49	22	results	result	NNS
cord-309582-ihrj84hr	49	23	[	[	-LRB-
cord-309582-ihrj84hr	49	24	14	14	CD
cord-309582-ihrj84hr	49	25	]	]	-RRB-
cord-309582-ihrj84hr	49	26	.	.	.
cord-309582-ihrj84hr	50	1	Most	Most	JJS
cord-309582-ihrj84hr	50	2	of	of	IN
cord-309582-ihrj84hr	50	3	the	the	DT
cord-309582-ihrj84hr	50	4	suggested	suggest	VBN
cord-309582-ihrj84hr	50	5	treatment	treatment	NN
cord-309582-ihrj84hr	50	6	medications	medication	NNS
cord-309582-ihrj84hr	50	7	are	be	VBP
cord-309582-ihrj84hr	50	8	based	base	VBN
cord-309582-ihrj84hr	50	9	on	on	IN
cord-309582-ihrj84hr	50	10	in	in	IN
cord-309582-ihrj84hr	50	11	vitro	vitro	FW
cord-309582-ihrj84hr	50	12	laboratory	laboratory	NN
cord-309582-ihrj84hr	50	13	investigations	investigation	NNS
cord-309582-ihrj84hr	50	14	,	,	,
cord-309582-ihrj84hr	50	15	experimental	experimental	JJ
cord-309582-ihrj84hr	50	16	animal	animal	NN
cord-309582-ihrj84hr	50	17	models	model	NNS
cord-309582-ihrj84hr	50	18	,	,	,
cord-309582-ihrj84hr	50	19	or	or	CC
cord-309582-ihrj84hr	50	20	previous	previous	JJ
cord-309582-ihrj84hr	50	21	experience	experience	NN
cord-309582-ihrj84hr	50	22	in	in	IN
cord-309582-ihrj84hr	50	23	treating	treat	VBG
cord-309582-ihrj84hr	50	24	similar	similar	JJ
cord-309582-ihrj84hr	50	25	viruses	virus	NNS
cord-309582-ihrj84hr	50	26	such	such	JJ
cord-309582-ihrj84hr	50	27	as	as	IN
cord-309582-ihrj84hr	50	28	SARS	SARS	NNP
cord-309582-ihrj84hr	50	29	-	-	HYPH
cord-309582-ihrj84hr	50	30	CoV-1	CoV-1	NNP
cord-309582-ihrj84hr	50	31	or	or	CC
cord-309582-ihrj84hr	50	32	other	other	JJ
cord-309582-ihrj84hr	50	33	retroviral	retroviral	JJ
cord-309582-ihrj84hr	50	34	infections	infection	NNS
cord-309582-ihrj84hr	50	35	.	.	.
cord-309582-ihrj84hr	51	1	It	-PRON-	PRP
cord-309582-ihrj84hr	51	2	is	be	VBZ
cord-309582-ihrj84hr	51	3	important	important	JJ
cord-309582-ihrj84hr	51	4	to	to	TO
cord-309582-ihrj84hr	51	5	note	note	VB
cord-309582-ihrj84hr	51	6	that	that	IN
cord-309582-ihrj84hr	51	7	in	in	IN
cord-309582-ihrj84hr	51	8	most	most	JJS
cord-309582-ihrj84hr	51	9	of	of	IN
cord-309582-ihrj84hr	51	10	these	these	DT
cord-309582-ihrj84hr	51	11	trials	trial	NNS
cord-309582-ihrj84hr	51	12	there	there	EX
cord-309582-ihrj84hr	51	13	was	be	VBD
cord-309582-ihrj84hr	51	14	no	no	DT
cord-309582-ihrj84hr	51	15	control	control	NN
cord-309582-ihrj84hr	51	16	group	group	NN
cord-309582-ihrj84hr	51	17	,	,	,
cord-309582-ihrj84hr	51	18	therefore	therefore	RB
cord-309582-ihrj84hr	51	19	the	the	DT
cord-309582-ihrj84hr	51	20	safety	safety	NN
cord-309582-ihrj84hr	51	21	profile	profile	NN
cord-309582-ihrj84hr	51	22	and	and	CC
cord-309582-ihrj84hr	51	23	effectiveness	effectiveness	NN
cord-309582-ihrj84hr	51	24	of	of	IN
cord-309582-ihrj84hr	51	25	the	the	DT
cord-309582-ihrj84hr	51	26	studied	study	VBN
cord-309582-ihrj84hr	51	27	medications	medication	NNS
cord-309582-ihrj84hr	51	28	can	can	MD
cord-309582-ihrj84hr	51	29	not	not	RB
cord-309582-ihrj84hr	51	30	be	be	VB
cord-309582-ihrj84hr	51	31	accurately	accurately	RB
cord-309582-ihrj84hr	51	32	determined	determine	VBN
cord-309582-ihrj84hr	51	33	.	.	.
cord-309582-ihrj84hr	52	1	Due	due	IN
cord-309582-ihrj84hr	52	2	to	to	IN
cord-309582-ihrj84hr	52	3	the	the	DT
cord-309582-ihrj84hr	52	4	very	very	RB
cord-309582-ihrj84hr	52	5	contagious	contagious	JJ
cord-309582-ihrj84hr	52	6	nature	nature	NN
cord-309582-ihrj84hr	52	7	of	of	IN
cord-309582-ihrj84hr	52	8	SARS	SARS	NNP
cord-309582-ihrj84hr	52	9	-	-	HYPH
cord-309582-ihrj84hr	52	10	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	52	11	,	,	,
cord-309582-ihrj84hr	52	12	overwhelming	overwhelm	VBG
cord-309582-ihrj84hr	52	13	the	the	DT
cord-309582-ihrj84hr	52	14	capacity	capacity	NN
cord-309582-ihrj84hr	52	15	of	of	IN
cord-309582-ihrj84hr	52	16	the	the	DT
cord-309582-ihrj84hr	52	17	health	health	NN
cord-309582-ihrj84hr	52	18	care	care	NN
cord-309582-ihrj84hr	52	19	system	system	NN
cord-309582-ihrj84hr	52	20	including	include	VBG
cord-309582-ihrj84hr	52	21	out	out	IN
cord-309582-ihrj84hr	52	22	-	-	HYPH
cord-309582-ihrj84hr	52	23	patient	patient	NN
cord-309582-ihrj84hr	52	24	clinics	clinic	NNS
cord-309582-ihrj84hr	52	25	,	,	,
cord-309582-ihrj84hr	52	26	in	in	IN
cord-309582-ihrj84hr	52	27	-	-	HYPH
cord-309582-ihrj84hr	52	28	hospital	hospital	NN
cord-309582-ihrj84hr	52	29	wards	ward	NNS
cord-309582-ihrj84hr	52	30	and	and	CC
cord-309582-ihrj84hr	52	31	ICUs	ICUs	NNP
cord-309582-ihrj84hr	52	32	,	,	,
cord-309582-ihrj84hr	52	33	and	and	CC
cord-309582-ihrj84hr	52	34	in	in	IN
cord-309582-ihrj84hr	52	35	light	light	NN
cord-309582-ihrj84hr	52	36	of	of	IN
cord-309582-ihrj84hr	52	37	the	the	DT
cord-309582-ihrj84hr	52	38	significant	significant	JJ
cord-309582-ihrj84hr	52	39	mortality	mortality	NN
cord-309582-ihrj84hr	52	40	in	in	IN
cord-309582-ihrj84hr	52	41	the	the	DT
cord-309582-ihrj84hr	52	42	absence	absence	NN
cord-309582-ihrj84hr	52	43	of	of	IN
cord-309582-ihrj84hr	52	44	effective	effective	JJ
cord-309582-ihrj84hr	52	45	treatment	treatment	NN
cord-309582-ihrj84hr	52	46	or	or	CC
cord-309582-ihrj84hr	52	47	prophylactic	prophylactic	JJ
cord-309582-ihrj84hr	52	48	vaccination	vaccination	NN
cord-309582-ihrj84hr	52	49	,	,	,
cord-309582-ihrj84hr	52	50	focused	focus	VBD
cord-309582-ihrj84hr	52	51	medical	medical	JJ
cord-309582-ihrj84hr	52	52	research	research	NN
cord-309582-ihrj84hr	52	53	on	on	IN
cord-309582-ihrj84hr	52	54	SARS	SARS	NNP
cord-309582-ihrj84hr	52	55	-	-	HYPH
cord-309582-ihrj84hr	52	56	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	52	57	is	be	VBZ
cord-309582-ihrj84hr	52	58	a	a	DT
cord-309582-ihrj84hr	52	59	necessity	necessity	NN
cord-309582-ihrj84hr	52	60	during	during	IN
cord-309582-ihrj84hr	52	61	this	this	DT
cord-309582-ihrj84hr	52	62	pandemic	pandemic	NN
cord-309582-ihrj84hr	52	63	,	,	,
cord-309582-ihrj84hr	52	64	with	with	IN
cord-309582-ihrj84hr	52	65	all	all	DT
cord-309582-ihrj84hr	52	66	patients	patient	NNS
cord-309582-ihrj84hr	52	67	deserving	deserve	VBG
cord-309582-ihrj84hr	52	68	evidence	evidence	NN
cord-309582-ihrj84hr	52	69	-	-	HYPH
cord-309582-ihrj84hr	52	70	based	base	VBN
cord-309582-ihrj84hr	52	71	care	care	NN
cord-309582-ihrj84hr	52	72	.	.	.
cord-309582-ihrj84hr	53	1	The	the	DT
cord-309582-ihrj84hr	53	2	entire	entire	JJ
cord-309582-ihrj84hr	53	3	world	world	NN
cord-309582-ihrj84hr	53	4	needs	need	VBZ
cord-309582-ihrj84hr	53	5	a	a	DT
cord-309582-ihrj84hr	53	6	coordinated	coordinated	JJ
cord-309582-ihrj84hr	53	7	effort	effort	NN
cord-309582-ihrj84hr	53	8	of	of	IN
cord-309582-ihrj84hr	53	9	all	all	PDT
cord-309582-ihrj84hr	53	10	the	the	DT
cord-309582-ihrj84hr	53	11	available	available	JJ
cord-309582-ihrj84hr	53	12	knowledge	knowledge	NN
cord-309582-ihrj84hr	53	13	and	and	CC
cord-309582-ihrj84hr	53	14	resources	resource	NNS
cord-309582-ihrj84hr	53	15	to	to	TO
cord-309582-ihrj84hr	53	16	fight	fight	VB
cord-309582-ihrj84hr	53	17	this	this	DT
cord-309582-ihrj84hr	53	18	pandemic	pandemic	NN
cord-309582-ihrj84hr	53	19	and	and	CC
cord-309582-ihrj84hr	53	20	possibly	possibly	RB
cord-309582-ihrj84hr	53	21	similar	similar	JJ
cord-309582-ihrj84hr	53	22	future	future	JJ
cord-309582-ihrj84hr	53	23	pandemics	pandemic	NNS
cord-309582-ihrj84hr	53	24	.	.	.
cord-309582-ihrj84hr	54	1	But	but	CC
cord-309582-ihrj84hr	54	2	it	-PRON-	PRP
cord-309582-ihrj84hr	54	3	is	be	VBZ
cord-309582-ihrj84hr	54	4	challenging	challenge	VBG
cord-309582-ihrj84hr	54	5	to	to	TO
cord-309582-ihrj84hr	54	6	conduct	conduct	VB
cord-309582-ihrj84hr	54	7	research	research	NN
cord-309582-ihrj84hr	54	8	during	during	IN
cord-309582-ihrj84hr	54	9	pandemics	pandemic	NNS
cord-309582-ihrj84hr	54	10	.	.	.
cord-309582-ihrj84hr	55	1	Indeed	indeed	RB
cord-309582-ihrj84hr	55	2	,	,	,
cord-309582-ihrj84hr	55	3	the	the	DT
cord-309582-ihrj84hr	55	4	running	running	NN
cord-309582-ihrj84hr	55	5	of	of	IN
cord-309582-ihrj84hr	55	6	clinical	clinical	JJ
cord-309582-ihrj84hr	55	7	trials	trial	NNS
cord-309582-ihrj84hr	55	8	during	during	IN
cord-309582-ihrj84hr	55	9	a	a	DT
cord-309582-ihrj84hr	55	10	pandemic	pandemic	NN
cord-309582-ihrj84hr	55	11	is	be	VBZ
cord-309582-ihrj84hr	55	12	affected	affect	VBN
cord-309582-ihrj84hr	55	13	at	at	IN
cord-309582-ihrj84hr	55	14	multiple	multiple	JJ
cord-309582-ihrj84hr	55	15	levels	level	NNS
cord-309582-ihrj84hr	55	16	.	.	.
cord-309582-ihrj84hr	56	1	Reasons	reason	NNS
cord-309582-ihrj84hr	56	2	for	for	IN
cord-309582-ihrj84hr	56	3	this	this	DT
cord-309582-ihrj84hr	56	4	include	include	VBP
cord-309582-ihrj84hr	56	5	patient	patient	JJ
cord-309582-ihrj84hr	56	6	hesitancy	hesitancy	NN
cord-309582-ihrj84hr	56	7	or	or	CC
cord-309582-ihrj84hr	56	8	inability	inability	NN
cord-309582-ihrj84hr	56	9	to	to	TO
cord-309582-ihrj84hr	56	10	continue	continue	VB
cord-309582-ihrj84hr	56	11	investigative	investigative	JJ
cord-309582-ihrj84hr	56	12	treatments	treatment	NNS
cord-309582-ihrj84hr	56	13	due	due	JJ
cord-309582-ihrj84hr	56	14	to	to	IN
cord-309582-ihrj84hr	56	15	selfisolation	selfisolation	NN
cord-309582-ihrj84hr	56	16	/	/	SYM
cord-309582-ihrj84hr	56	17	quarantine	quarantine	NN
cord-309582-ihrj84hr	56	18	,	,	,
cord-309582-ihrj84hr	56	19	or	or	CC
cord-309582-ihrj84hr	56	20	limited	limited	JJ
cord-309582-ihrj84hr	56	21	access	access	NN
cord-309582-ihrj84hr	56	22	to	to	IN
cord-309582-ihrj84hr	56	23	public	public	JJ
cord-309582-ihrj84hr	56	24	places	place	NNS
cord-309582-ihrj84hr	56	25	(	(	-LRB-
cord-309582-ihrj84hr	56	26	including	include	VBG
cord-309582-ihrj84hr	56	27	hospitals	hospital	NNS
cord-309582-ihrj84hr	56	28	)	)	-RRB-
cord-309582-ihrj84hr	56	29	.	.	.
cord-309582-ihrj84hr	57	1	Additional	additional	JJ
cord-309582-ihrj84hr	57	2	barriers	barrier	NNS
cord-309582-ihrj84hr	57	3	relate	relate	VBP
cord-309582-ihrj84hr	57	4	to	to	IN
cord-309582-ihrj84hr	57	5	health	health	NN
cord-309582-ihrj84hr	57	6	care	care	NN
cord-309582-ihrj84hr	57	7	professionals	professional	NNS
cord-309582-ihrj84hr	57	8	being	be	VBG
cord-309582-ihrj84hr	57	9	committed	commit	VBN
cord-309582-ihrj84hr	57	10	to	to	IN
cord-309582-ihrj84hr	57	11	other	other	JJ
cord-309582-ihrj84hr	57	12	critical	critical	JJ
cord-309582-ihrj84hr	57	13	tasks	task	NNS
cord-309582-ihrj84hr	57	14	or	or	CC
cord-309582-ihrj84hr	57	15	quarantining	quarantine	VBG
cord-309582-ihrj84hr	57	16	themselves	-PRON-	PRP
cord-309582-ihrj84hr	57	17	due	due	JJ
cord-309582-ihrj84hr	57	18	to	to	IN
cord-309582-ihrj84hr	57	19	contact	contact	NN
cord-309582-ihrj84hr	57	20	with	with	IN
cord-309582-ihrj84hr	57	21	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	57	22	positive	positive	JJ
cord-309582-ihrj84hr	57	23	patients	patient	NNS
cord-309582-ihrj84hr	57	24	[	[	-LRB-
cord-309582-ihrj84hr	57	25	15	15	CD
cord-309582-ihrj84hr	57	26	]	]	-RRB-
cord-309582-ihrj84hr	57	27	.	.	.
cord-309582-ihrj84hr	58	1	Interruption	interruption	NN
cord-309582-ihrj84hr	58	2	of	of	IN
cord-309582-ihrj84hr	58	3	supply	supply	NN
cord-309582-ihrj84hr	58	4	chains	chain	NNS
cord-309582-ihrj84hr	58	5	and	and	CC
cord-309582-ihrj84hr	58	6	monitoring	monitoring	NN
cord-309582-ihrj84hr	58	7	of	of	IN
cord-309582-ihrj84hr	58	8	clinical	clinical	JJ
cord-309582-ihrj84hr	58	9	trials	trial	NNS
cord-309582-ihrj84hr	58	10	are	be	VBP
cord-309582-ihrj84hr	58	11	additional	additional	JJ
cord-309582-ihrj84hr	58	12	obstacles	obstacle	NNS
cord-309582-ihrj84hr	58	13	to	to	IN
cord-309582-ihrj84hr	58	14	medical	medical	JJ
cord-309582-ihrj84hr	58	15	research	research	NN
cord-309582-ihrj84hr	58	16	during	during	IN
cord-309582-ihrj84hr	58	17	pandemics	pandemic	NNS
cord-309582-ihrj84hr	58	18	(	(	-LRB-
cord-309582-ihrj84hr	58	19	Figure	figure	NN
cord-309582-ihrj84hr	58	20	1	1	CD
cord-309582-ihrj84hr	58	21	)	)	-RRB-
cord-309582-ihrj84hr	58	22	.	.	.
cord-309582-ihrj84hr	59	1	The	the	DT
cord-309582-ihrj84hr	59	2	best	good	JJS
cord-309582-ihrj84hr	59	3	research	research	NN
cord-309582-ihrj84hr	59	4	approaches	approach	NNS
cord-309582-ihrj84hr	59	5	are	be	VBP
cord-309582-ihrj84hr	59	6	those	those	DT
cord-309582-ihrj84hr	59	7	that	that	WDT
cord-309582-ihrj84hr	59	8	will	will	MD
cord-309582-ihrj84hr	59	9	adapt	adapt	VB
cord-309582-ihrj84hr	59	10	to	to	IN
cord-309582-ihrj84hr	59	11	such	such	JJ
cord-309582-ihrj84hr	59	12	external	external	JJ
cord-309582-ihrj84hr	59	13	unplanned	unplanned	JJ
cord-309582-ihrj84hr	59	14	obstacles	obstacle	NNS
cord-309582-ihrj84hr	59	15	.	.	.
cord-309582-ihrj84hr	60	1	As	as	IN
cord-309582-ihrj84hr	60	2	example	example	NN
cord-309582-ihrj84hr	60	3	,	,	,
cord-309582-ihrj84hr	60	4	similar	similar	JJ
cord-309582-ihrj84hr	60	5	to	to	IN
cord-309582-ihrj84hr	60	6	other	other	JJ
cord-309582-ihrj84hr	60	7	research	research	NN
cord-309582-ihrj84hr	60	8	institutions	institution	NNS
cord-309582-ihrj84hr	60	9	,	,	,
cord-309582-ihrj84hr	60	10	we	-PRON-	PRP
cord-309582-ihrj84hr	60	11	are	be	VBP
cord-309582-ihrj84hr	60	12	facing	face	VBG
cord-309582-ihrj84hr	60	13	many	many	JJ
cord-309582-ihrj84hr	60	14	challenges	challenge	NNS
cord-309582-ihrj84hr	60	15	and	and	CC
cord-309582-ihrj84hr	60	16	obstacles	obstacle	NNS
cord-309582-ihrj84hr	60	17	at	at	IN
cord-309582-ihrj84hr	60	18	our	-PRON-	PRP$
cord-309582-ihrj84hr	60	19	own	own	JJ
cord-309582-ihrj84hr	60	20	centers	center	NNS
cord-309582-ihrj84hr	60	21	.	.	.
cord-309582-ihrj84hr	61	1	Perhaps	perhaps	RB
cord-309582-ihrj84hr	61	2	one	one	CD
cord-309582-ihrj84hr	61	3	of	of	IN
cord-309582-ihrj84hr	61	4	the	the	DT
cord-309582-ihrj84hr	61	5	most	most	RBS
cord-309582-ihrj84hr	61	6	important	important	JJ
cord-309582-ihrj84hr	61	7	barriers	barrier	NNS
cord-309582-ihrj84hr	61	8	are	be	VBP
cord-309582-ihrj84hr	61	9	a	a	DT
cord-309582-ihrj84hr	61	10	patient	patient	NN
cord-309582-ihrj84hr	61	11	's	's	POS
cord-309582-ihrj84hr	61	12	understandable	understandable	JJ
cord-309582-ihrj84hr	61	13	anxiety	anxiety	NN
cord-309582-ihrj84hr	61	14	and	and	CC
cord-309582-ihrj84hr	61	15	fear	fear	NN
cord-309582-ihrj84hr	61	16	related	relate	VBN
cord-309582-ihrj84hr	61	17	to	to	IN
cord-309582-ihrj84hr	61	18	the	the	DT
cord-309582-ihrj84hr	61	19	current	current	JJ
cord-309582-ihrj84hr	61	20	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	61	21	pandemic	pandemic	NN
cord-309582-ihrj84hr	61	22	.	.	.
cord-309582-ihrj84hr	62	1	Indeed	indeed	RB
cord-309582-ihrj84hr	62	2	,	,	,
cord-309582-ihrj84hr	62	3	they	-PRON-	PRP
cord-309582-ihrj84hr	62	4	are	be	VBP
cord-309582-ihrj84hr	62	5	very	very	RB
cord-309582-ihrj84hr	62	6	hesitant	hesitant	JJ
cord-309582-ihrj84hr	62	7	to	to	TO
cord-309582-ihrj84hr	62	8	visit	visit	VB
cord-309582-ihrj84hr	62	9	health	health	NN
cord-309582-ihrj84hr	62	10	care	care	NN
cord-309582-ihrj84hr	62	11	facilities	facility	NNS
cord-309582-ihrj84hr	62	12	to	to	TO
cord-309582-ihrj84hr	62	13	participate	participate	VB
cord-309582-ihrj84hr	62	14	in	in	IN
cord-309582-ihrj84hr	62	15	new	new	JJ
cord-309582-ihrj84hr	62	16	clinical	clinical	JJ
cord-309582-ihrj84hr	62	17	trials	trial	NNS
cord-309582-ihrj84hr	62	18	,	,	,
cord-309582-ihrj84hr	62	19	let	let	VB
cord-309582-ihrj84hr	62	20	alone	alone	RB
cord-309582-ihrj84hr	62	21	continue	continue	VB
cord-309582-ihrj84hr	62	22	in	in	IN
cord-309582-ihrj84hr	62	23	ongoing	ongoing	JJ
cord-309582-ihrj84hr	62	24	ones	one	NNS
cord-309582-ihrj84hr	62	25	.	.	.
cord-309582-ihrj84hr	63	1	Some	some	DT
cord-309582-ihrj84hr	63	2	patients	patient	NNS
cord-309582-ihrj84hr	63	3	have	have	VBP
cord-309582-ihrj84hr	63	4	also	also	RB
cord-309582-ihrj84hr	63	5	been	be	VBN
cord-309582-ihrj84hr	63	6	quarantined	quarantine	VBN
cord-309582-ihrj84hr	63	7	due	due	IN
cord-309582-ihrj84hr	63	8	to	to	IN
cord-309582-ihrj84hr	63	9	contact	contact	NN
cord-309582-ihrj84hr	63	10	with	with	IN
cord-309582-ihrj84hr	63	11	confirmed	confirm	VBN
cord-309582-ihrj84hr	63	12	COVID-19	covid-19	CD
cord-309582-ihrj84hr	63	13	cases	case	NNS
cord-309582-ihrj84hr	63	14	.	.	.
cord-309582-ihrj84hr	64	1	Investigators	investigator	NNS
cord-309582-ihrj84hr	64	2	at	at	IN
cord-309582-ihrj84hr	64	3	our	-PRON-	PRP$
cord-309582-ihrj84hr	64	4	institutions	institution	NNS
cord-309582-ihrj84hr	64	5	especially	especially	RB
cord-309582-ihrj84hr	64	6	those	those	DT
cord-309582-ihrj84hr	64	7	involved	involve	VBN
cord-309582-ihrj84hr	64	8	in	in	IN
cord-309582-ihrj84hr	64	9	sponsored	sponsor	VBN
cord-309582-ihrj84hr	64	10	clinical	clinical	JJ
cord-309582-ihrj84hr	64	11	trials	trial	NNS
cord-309582-ihrj84hr	64	12	are	be	VBP
cord-309582-ihrj84hr	64	13	also	also	RB
cord-309582-ihrj84hr	64	14	facing	face	VBG
cord-309582-ihrj84hr	64	15	challenges	challenge	NNS
cord-309582-ihrj84hr	64	16	related	relate	VBN
cord-309582-ihrj84hr	64	17	to	to	IN
cord-309582-ihrj84hr	64	18	interruptions	interruption	NNS
cord-309582-ihrj84hr	64	19	in	in	IN
cord-309582-ihrj84hr	64	20	the	the	DT
cord-309582-ihrj84hr	64	21	supply	supply	NN
cord-309582-ihrj84hr	64	22	chains	chain	NNS
cord-309582-ihrj84hr	64	23	for	for	IN
cord-309582-ihrj84hr	64	24	investigational	investigational	JJ
cord-309582-ihrj84hr	64	25	products	product	NNS
cord-309582-ihrj84hr	64	26	,	,	,
cord-309582-ihrj84hr	64	27	coupled	couple	VBN
cord-309582-ihrj84hr	64	28	to	to	IN
cord-309582-ihrj84hr	64	29	the	the	DT
cord-309582-ihrj84hr	64	30	inability	inability	NN
cord-309582-ihrj84hr	64	31	of	of	IN
cord-309582-ihrj84hr	64	32	trial	trial	NN
cord-309582-ihrj84hr	64	33	personnel	personnel	NNS
cord-309582-ihrj84hr	64	34	to	to	TO
cord-309582-ihrj84hr	64	35	perform	perform	VB
cord-309582-ihrj84hr	64	36	visits	visit	NNS
cord-309582-ihrj84hr	64	37	and/or	and/or	CC
cord-309582-ihrj84hr	64	38	investigations	investigation	NNS
cord-309582-ihrj84hr	64	39	on	on	IN
cord-309582-ihrj84hr	64	40	enrolled	enrol	VBN
cord-309582-ihrj84hr	64	41	patients	patient	NNS
cord-309582-ihrj84hr	64	42	.	.	.
cord-309582-ihrj84hr	65	1	Ethics	ethic	NNS
cord-309582-ihrj84hr	65	2	committees	committee	NNS
cord-309582-ihrj84hr	65	3	must	must	MD
cord-309582-ihrj84hr	65	4	apply	apply	VB
cord-309582-ihrj84hr	65	5	rigorous	rigorous	JJ
cord-309582-ihrj84hr	65	6	standards	standard	NNS
cord-309582-ihrj84hr	65	7	to	to	TO
cord-309582-ihrj84hr	65	8	authorize	authorize	VB
cord-309582-ihrj84hr	65	9	research	research	NN
cord-309582-ihrj84hr	65	10	in	in	IN
cord-309582-ihrj84hr	65	11	accordance	accordance	NN
cord-309582-ihrj84hr	65	12	with	with	IN
cord-309582-ihrj84hr	65	13	the	the	DT
cord-309582-ihrj84hr	65	14	principles	principle	NNS
cord-309582-ihrj84hr	65	15	of	of	IN
cord-309582-ihrj84hr	65	16	justice	justice	NN
cord-309582-ihrj84hr	65	17	,	,	,
cord-309582-ihrj84hr	65	18	equity	equity	NN
cord-309582-ihrj84hr	65	19	and	and	CC
cord-309582-ihrj84hr	65	20	solidarity	solidarity	NN
cord-309582-ihrj84hr	65	21	.	.	.
cord-309582-ihrj84hr	66	1	Lapses	lapse	NNS
cord-309582-ihrj84hr	66	2	were	be	VBD
cord-309582-ihrj84hr	66	3	reported	report	VBN
cord-309582-ihrj84hr	66	4	during	during	IN
cord-309582-ihrj84hr	66	5	previous	previous	JJ
cord-309582-ihrj84hr	66	6	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	66	7	such	such	JJ
cord-309582-ihrj84hr	66	8	as	as	IN
cord-309582-ihrj84hr	66	9	in	in	IN
cord-309582-ihrj84hr	66	10	the	the	DT
cord-309582-ihrj84hr	66	11	West	West	NNP
cord-309582-ihrj84hr	66	12	Africa	Africa	NNP
cord-309582-ihrj84hr	66	13	Ebola	Ebola	NNP
cord-309582-ihrj84hr	66	14	Virus	Virus	NNP
cord-309582-ihrj84hr	66	15	(	(	-LRB-
cord-309582-ihrj84hr	66	16	EV	ev	NN
cord-309582-ihrj84hr	66	17	)	)	-RRB-
cord-309582-ihrj84hr	66	18	outbreak	outbreak	NN
cord-309582-ihrj84hr	66	19	leading	lead	VBG
cord-309582-ihrj84hr	66	20	to	to	IN
cord-309582-ihrj84hr	66	21	incomplete	incomplete	JJ
cord-309582-ihrj84hr	66	22	studies	study	NNS
cord-309582-ihrj84hr	66	23	and	and	CC
cord-309582-ihrj84hr	66	24	inconclusive	inconclusive	JJ
cord-309582-ihrj84hr	66	25	results	result	NNS
cord-309582-ihrj84hr	66	26	[	[	-LRB-
cord-309582-ihrj84hr	66	27	16	16	CD
cord-309582-ihrj84hr	66	28	]	]	-RRB-
cord-309582-ihrj84hr	67	1	[	[	-LRB-
cord-309582-ihrj84hr	67	2	17	17	CD
cord-309582-ihrj84hr	67	3	]	]	-RRB-
cord-309582-ihrj84hr	67	4	[	[	-LRB-
cord-309582-ihrj84hr	67	5	18	18	CD
cord-309582-ihrj84hr	67	6	]	]	-RRB-
cord-309582-ihrj84hr	67	7	.	.	.
cord-309582-ihrj84hr	68	1	Although	although	IN
cord-309582-ihrj84hr	68	2	we	-PRON-	PRP
cord-309582-ihrj84hr	68	3	must	must	MD
cord-309582-ihrj84hr	68	4	strive	strive	VB
cord-309582-ihrj84hr	68	5	to	to	TO
cord-309582-ihrj84hr	68	6	avoid	avoid	VB
cord-309582-ihrj84hr	68	7	publication	publication	NN
cord-309582-ihrj84hr	68	8	bias	bias	NN
cord-309582-ihrj84hr	68	9	(	(	-LRB-
cord-309582-ihrj84hr	68	10	only	only	RB
cord-309582-ihrj84hr	68	11	submitting	submit	VBG
cord-309582-ihrj84hr	68	12	"	"	``
cord-309582-ihrj84hr	68	13	positive	positive	JJ
cord-309582-ihrj84hr	68	14	studies	study	NNS
cord-309582-ihrj84hr	68	15	"	"	''
cord-309582-ihrj84hr	68	16	)	)	-RRB-
cord-309582-ihrj84hr	68	17	,	,	,
cord-309582-ihrj84hr	68	18	the	the	DT
cord-309582-ihrj84hr	68	19	importance	importance	NN
cord-309582-ihrj84hr	68	20	of	of	IN
cord-309582-ihrj84hr	68	21	unpublished	unpublished	JJ
cord-309582-ihrj84hr	68	22	data	datum	NNS
cord-309582-ihrj84hr	68	23	or	or	CC
cord-309582-ihrj84hr	68	24	not	not	RB
cord-309582-ihrj84hr	68	25	publishing	publish	VBG
cord-309582-ihrj84hr	68	26	incomplete	incomplete	JJ
cord-309582-ihrj84hr	68	27	data	datum	NNS
cord-309582-ihrj84hr	68	28	and	and	CC
cord-309582-ihrj84hr	68	29	inconclusive	inconclusive	JJ
cord-309582-ihrj84hr	68	30	results	result	NNS
cord-309582-ihrj84hr	68	31	must	must	MD
cord-309582-ihrj84hr	68	32	also	also	RB
cord-309582-ihrj84hr	68	33	be	be	VB
cord-309582-ihrj84hr	68	34	stressed	stress	VBN
cord-309582-ihrj84hr	68	35	.	.	.
cord-309582-ihrj84hr	69	1	Take	take	VB
cord-309582-ihrj84hr	69	2	for	for	IN
cord-309582-ihrj84hr	69	3	example	example	NN
cord-309582-ihrj84hr	69	4	the	the	DT
cord-309582-ihrj84hr	69	5	randomized	randomized	JJ
cord-309582-ihrj84hr	69	6	controlled	control	VBN
cord-309582-ihrj84hr	69	7	trial	trial	NN
cord-309582-ihrj84hr	69	8	performed	perform	VBN
cord-309582-ihrj84hr	69	9	during	during	IN
cord-309582-ihrj84hr	69	10	an	an	DT
cord-309582-ihrj84hr	69	11	EV	EV	NNP
cord-309582-ihrj84hr	69	12	outbreak	outbreak	NN
cord-309582-ihrj84hr	69	13	in	in	IN
cord-309582-ihrj84hr	69	14	2014	2014	CD
cord-309582-ihrj84hr	69	15	looking	look	VBG
cord-309582-ihrj84hr	69	16	at	at	IN
cord-309582-ihrj84hr	69	17	a	a	DT
cord-309582-ihrj84hr	69	18	triple	triple	JJ
cord-309582-ihrj84hr	69	19	monoclonal	monoclonal	JJ
cord-309582-ihrj84hr	69	20	antibody	antibody	NN
cord-309582-ihrj84hr	69	21	cocktail	cocktail	NN
cord-309582-ihrj84hr	69	22	(	(	-LRB-
cord-309582-ihrj84hr	69	23	ZMapp	ZMapp	NNP
cord-309582-ihrj84hr	69	24	)	)	-RRB-
cord-309582-ihrj84hr	69	25	as	as	IN
cord-309582-ihrj84hr	69	26	treatment	treatment	NN
cord-309582-ihrj84hr	69	27	for	for	IN
cord-309582-ihrj84hr	69	28	EV	EV	NNP
cord-309582-ihrj84hr	69	29	.	.	.
cord-309582-ihrj84hr	70	1	The	the	DT
cord-309582-ihrj84hr	70	2	investigators	investigator	NNS
cord-309582-ihrj84hr	70	3	concluded	conclude	VBD
cord-309582-ihrj84hr	70	4	that	that	IN
cord-309582-ihrj84hr	70	5	the	the	DT
cord-309582-ihrj84hr	70	6	estimated	estimate	VBN
cord-309582-ihrj84hr	70	7	effect	effect	NN
cord-309582-ihrj84hr	70	8	of	of	IN
cord-309582-ihrj84hr	70	9	ZMapp	ZMapp	NNP
cord-309582-ihrj84hr	70	10	appeared	appear	VBD
cord-309582-ihrj84hr	70	11	to	to	TO
cord-309582-ihrj84hr	70	12	be	be	VB
cord-309582-ihrj84hr	70	13	beneficial	beneficial	JJ
cord-309582-ihrj84hr	70	14	,	,	,
cord-309582-ihrj84hr	70	15	but	but	CC
cord-309582-ihrj84hr	70	16	the	the	DT
cord-309582-ihrj84hr	70	17	results	result	NNS
cord-309582-ihrj84hr	70	18	in	in	IN
cord-309582-ihrj84hr	70	19	fact	fact	NN
cord-309582-ihrj84hr	70	20	did	do	VBD
cord-309582-ihrj84hr	70	21	not	not	RB
cord-309582-ihrj84hr	70	22	meet	meet	VB
cord-309582-ihrj84hr	70	23	the	the	DT
cord-309582-ihrj84hr	70	24	prespecified	prespecified	JJ
cord-309582-ihrj84hr	70	25	statistical	statistical	JJ
cord-309582-ihrj84hr	70	26	threshold	threshold	NN
cord-309582-ihrj84hr	70	27	for	for	IN
cord-309582-ihrj84hr	70	28	efficacy	efficacy	NN
cord-309582-ihrj84hr	70	29	,	,	,
cord-309582-ihrj84hr	70	30	thus	thus	RB
cord-309582-ihrj84hr	70	31	leading	lead	VBG
cord-309582-ihrj84hr	70	32	to	to	IN
cord-309582-ihrj84hr	70	33	an	an	DT
cord-309582-ihrj84hr	70	34	underpowered	underpowered	JJ
cord-309582-ihrj84hr	70	35	negative	negative	JJ
cord-309582-ihrj84hr	70	36	trial	trial	NN
cord-309582-ihrj84hr	70	37	[	[	-LRB-
cord-309582-ihrj84hr	70	38	18	18	CD
cord-309582-ihrj84hr	70	39	]	]	-RRB-
cord-309582-ihrj84hr	70	40	.	.	.
cord-309582-ihrj84hr	71	1	An	an	DT
cord-309582-ihrj84hr	71	2	example	example	NN
cord-309582-ihrj84hr	71	3	of	of	IN
cord-309582-ihrj84hr	71	4	unpublished	unpublished	JJ
cord-309582-ihrj84hr	71	5	results	result	NNS
cord-309582-ihrj84hr	71	6	that	that	WDT
cord-309582-ihrj84hr	71	7	need	need	VBP
cord-309582-ihrj84hr	71	8	to	to	TO
cord-309582-ihrj84hr	71	9	be	be	VB
cord-309582-ihrj84hr	71	10	widely	widely	RB
cord-309582-ihrj84hr	71	11	acknowledged	acknowledge	VBN
cord-309582-ihrj84hr	71	12	because	because	IN
cord-309582-ihrj84hr	71	13	of	of	IN
cord-309582-ihrj84hr	71	14	a	a	DT
cord-309582-ihrj84hr	71	15	negative	negative	JJ
cord-309582-ihrj84hr	71	16	outcome	outcome	NN
cord-309582-ihrj84hr	71	17	leading	lead	VBG
cord-309582-ihrj84hr	71	18	to	to	IN
cord-309582-ihrj84hr	71	19	early	early	JJ
cord-309582-ihrj84hr	71	20	termination	termination	NN
cord-309582-ihrj84hr	71	21	is	be	VBZ
cord-309582-ihrj84hr	71	22	that	that	DT
cord-309582-ihrj84hr	71	23	of	of	IN
cord-309582-ihrj84hr	71	24	a	a	DT
cord-309582-ihrj84hr	71	25	Brazilian	brazilian	JJ
cord-309582-ihrj84hr	71	26	study	study	NN
cord-309582-ihrj84hr	71	27	(	(	-LRB-
cord-309582-ihrj84hr	71	28	CloroCovid-	clorocovid-	NN
cord-309582-ihrj84hr	71	29	19	19	CD
cord-309582-ihrj84hr	71	30	)	)	-RRB-
cord-309582-ihrj84hr	71	31	which	which	WDT
cord-309582-ihrj84hr	71	32	was	be	VBD
cord-309582-ihrj84hr	71	33	a	a	DT
cord-309582-ihrj84hr	71	34	parallel	parallel	JJ
cord-309582-ihrj84hr	71	35	,	,	,
cord-309582-ihrj84hr	71	36	double	double	JJ
cord-309582-ihrj84hr	71	37	-	-	HYPH
cord-309582-ihrj84hr	71	38	blind	blind	JJ
cord-309582-ihrj84hr	71	39	,	,	,
cord-309582-ihrj84hr	71	40	randomized	randomized	JJ
cord-309582-ihrj84hr	71	41	,	,	,
cord-309582-ihrj84hr	71	42	phase	phase	NN
cord-309582-ihrj84hr	71	43	IIb	iib	JJ
cord-309582-ihrj84hr	71	44	clinical	clinical	JJ
cord-309582-ihrj84hr	71	45	trial	trial	NN
cord-309582-ihrj84hr	71	46	,	,	,
cord-309582-ihrj84hr	71	47	which	which	WDT
cord-309582-ihrj84hr	71	48	started	start	VBD
cord-309582-ihrj84hr	71	49	on	on	IN
cord-309582-ihrj84hr	71	50	March	March	NNP
cord-309582-ihrj84hr	71	51	23	23	CD
cord-309582-ihrj84hr	71	52	,	,	,
cord-309582-ihrj84hr	71	53	2020	2020	CD
cord-309582-ihrj84hr	71	54	,	,	,
cord-309582-ihrj84hr	71	55	aiming	aim	VBG
cord-309582-ihrj84hr	71	56	to	to	TO
cord-309582-ihrj84hr	71	57	assess	assess	VB
cord-309582-ihrj84hr	71	58	safety	safety	NN
cord-309582-ihrj84hr	71	59	and	and	CC
cord-309582-ihrj84hr	71	60	efficacy	efficacy	NN
cord-309582-ihrj84hr	71	61	of	of	IN
cord-309582-ihrj84hr	71	62	Chloroquine	Chloroquine	NNP
cord-309582-ihrj84hr	71	63	diphosphate	diphosphate	NN
cord-309582-ihrj84hr	71	64	(	(	-LRB-
cord-309582-ihrj84hr	71	65	CQ	CQ	NNP
cord-309582-ihrj84hr	71	66	)	)	-RRB-
cord-309582-ihrj84hr	71	67	in	in	IN
cord-309582-ihrj84hr	71	68	the	the	DT
cord-309582-ihrj84hr	71	69	treatment	treatment	NN
cord-309582-ihrj84hr	71	70	of	of	IN
cord-309582-ihrj84hr	71	71	hospitalized	hospitalize	VBN
cord-309582-ihrj84hr	71	72	patients	patient	NNS
cord-309582-ihrj84hr	71	73	with	with	IN
cord-309582-ihrj84hr	71	74	severe	severe	JJ
cord-309582-ihrj84hr	71	75	respiratory	respiratory	JJ
cord-309582-ihrj84hr	71	76	syndrome	syndrome	NN
cord-309582-ihrj84hr	71	77	secondary	secondary	JJ
cord-309582-ihrj84hr	71	78	to	to	IN
cord-309582-ihrj84hr	71	79	SARS	SARS	NNP
cord-309582-ihrj84hr	71	80	-	-	HYPH
cord-309582-ihrj84hr	71	81	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	71	82	infection	infection	NN
cord-309582-ihrj84hr	71	83	.	.	.
cord-309582-ihrj84hr	72	1	The	the	DT
cord-309582-ihrj84hr	72	2	high	high	JJ
cord-309582-ihrj84hr	72	3	dose	dose	NN
cord-309582-ihrj84hr	72	4	of	of	IN
cord-309582-ihrj84hr	72	5	CQ	CQ	NNP
cord-309582-ihrj84hr	72	6	600	600	CD
cord-309582-ihrj84hr	72	7	mg	mg	NN
cord-309582-ihrj84hr	72	8	at	at	IN
cord-309582-ihrj84hr	72	9	twice	twice	RB
cord-309582-ihrj84hr	72	10	daily	daily	RB
cord-309582-ihrj84hr	72	11	for	for	IN
cord-309582-ihrj84hr	72	12	10	10	CD
cord-309582-ihrj84hr	72	13	d	d	NN
cord-309582-ihrj84hr	72	14	led	lead	VBD
cord-309582-ihrj84hr	72	15	to	to	IN
cord-309582-ihrj84hr	72	16	a	a	DT
cord-309582-ihrj84hr	72	17	higher	high	JJR
cord-309582-ihrj84hr	72	18	fatality	fatality	NN
cord-309582-ihrj84hr	72	19	rate	rate	NN
cord-309582-ihrj84hr	72	20	(	(	-LRB-
cord-309582-ihrj84hr	72	21	27	27	CD
cord-309582-ihrj84hr	72	22	%	%	NN
cord-309582-ihrj84hr	72	23	)	)	-RRB-
cord-309582-ihrj84hr	72	24	by	by	IN
cord-309582-ihrj84hr	72	25	day	day	NN
cord-309582-ihrj84hr	72	26	13	13	CD
cord-309582-ihrj84hr	72	27	of	of	IN
cord-309582-ihrj84hr	72	28	the	the	DT
cord-309582-ihrj84hr	72	29	trial	trial	NN
cord-309582-ihrj84hr	72	30	compared	compare	VBN
cord-309582-ihrj84hr	72	31	to	to	IN
cord-309582-ihrj84hr	72	32	the	the	DT
cord-309582-ihrj84hr	72	33	lower	low	JJR
cord-309582-ihrj84hr	72	34	dose	dose	NN
cord-309582-ihrj84hr	72	35	group	group	NN
cord-309582-ihrj84hr	72	36	and	and	CC
cord-309582-ihrj84hr	72	37	historical	historical	JJ
cord-309582-ihrj84hr	72	38	data	datum	NNS
cord-309582-ihrj84hr	72	39	from	from	IN
cord-309582-ihrj84hr	72	40	similar	similar	JJ
cord-309582-ihrj84hr	72	41	patients	patient	NNS
cord-309582-ihrj84hr	72	42	not	not	RB
cord-309582-ihrj84hr	72	43	using	use	VBG
cord-309582-ihrj84hr	72	44	CQ	CQ	NNP
cord-309582-ihrj84hr	72	45	[	[	-LRB-
cord-309582-ihrj84hr	72	46	19	19	CD
cord-309582-ihrj84hr	72	47	]	]	-RRB-
cord-309582-ihrj84hr	72	48	.	.	.
cord-309582-ihrj84hr	73	1	Medical	medical	JJ
cord-309582-ihrj84hr	73	2	research	research	NN
cord-309582-ihrj84hr	73	3	must	must	MD
cord-309582-ihrj84hr	73	4	therefore	therefore	RB
cord-309582-ihrj84hr	73	5	be	be	VB
cord-309582-ihrj84hr	73	6	adapted	adapt	VBN
cord-309582-ihrj84hr	73	7	to	to	IN
cord-309582-ihrj84hr	73	8	the	the	DT
cord-309582-ihrj84hr	73	9	new	new	JJ
cord-309582-ihrj84hr	73	10	socio	socio	JJ
cord-309582-ihrj84hr	73	11	-	-	HYPH
cord-309582-ihrj84hr	73	12	economic	economic	JJ
cord-309582-ihrj84hr	73	13	reality	reality	NN
cord-309582-ihrj84hr	73	14	during	during	IN
cord-309582-ihrj84hr	73	15	the	the	DT
cord-309582-ihrj84hr	73	16	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	73	17	pandemic	pandemic	NN
cord-309582-ihrj84hr	73	18	.	.	.
cord-309582-ihrj84hr	74	1	Such	such	JJ
cord-309582-ihrj84hr	74	2	studies	study	NNS
cord-309582-ihrj84hr	74	3	can	can	MD
cord-309582-ihrj84hr	74	4	be	be	VB
cord-309582-ihrj84hr	74	5	divided	divide	VBN
cord-309582-ihrj84hr	74	6	into	into	IN
cord-309582-ihrj84hr	74	7	three	three	CD
cord-309582-ihrj84hr	74	8	main	main	JJ
cord-309582-ihrj84hr	74	9	categories	category	NNS
cord-309582-ihrj84hr	74	10	:	:	:
cord-309582-ihrj84hr	74	11	Ongoing	ongoing	JJ
cord-309582-ihrj84hr	74	12	medical	medical	JJ
cord-309582-ihrj84hr	74	13	research	research	NN
cord-309582-ihrj84hr	74	14	that	that	WDT
cord-309582-ihrj84hr	74	15	antedated	antedate	VBD
cord-309582-ihrj84hr	74	16	the	the	DT
cord-309582-ihrj84hr	74	17	pandemic	pandemic	NN
cord-309582-ihrj84hr	74	18	,	,	,
cord-309582-ihrj84hr	74	19	new	new	JJ
cord-309582-ihrj84hr	74	20	research	research	NN
cord-309582-ihrj84hr	74	21	that	that	WDT
cord-309582-ihrj84hr	74	22	is	be	VBZ
cord-309582-ihrj84hr	74	23	initiated	initiate	VBN
cord-309582-ihrj84hr	74	24	during	during	IN
cord-309582-ihrj84hr	74	25	the	the	DT
cord-309582-ihrj84hr	74	26	pandemic	pandemic	NN
cord-309582-ihrj84hr	74	27	,	,	,
cord-309582-ihrj84hr	74	28	and	and	CC
cord-309582-ihrj84hr	74	29	future	future	JJ
cord-309582-ihrj84hr	74	30	research	research	NN
cord-309582-ihrj84hr	74	31	on	on	IN
cord-309582-ihrj84hr	74	32	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	74	33	that	that	WDT
cord-309582-ihrj84hr	74	34	will	will	MD
cord-309582-ihrj84hr	74	35	follow	follow	VB
cord-309582-ihrj84hr	74	36	it	-PRON-	PRP
cord-309582-ihrj84hr	74	37	.	.	.
cord-309582-ihrj84hr	75	1	standard	standard	NN
cord-309582-ihrj84hr	75	2	of	of	IN
cord-309582-ihrj84hr	75	3	care	care	NN
cord-309582-ihrj84hr	75	4	and	and	CC
cord-309582-ihrj84hr	75	5	may	may	MD
cord-309582-ihrj84hr	75	6	represent	represent	VB
cord-309582-ihrj84hr	75	7	a	a	DT
cord-309582-ihrj84hr	75	8	patient	patient	NN
cord-309582-ihrj84hr	75	9	's	's	POS
cord-309582-ihrj84hr	75	10	only	only	JJ
cord-309582-ihrj84hr	75	11	hope	hope	NN
cord-309582-ihrj84hr	75	12	.	.	.
cord-309582-ihrj84hr	76	1	Furthermore	furthermore	RB
cord-309582-ihrj84hr	76	2	,	,	,
cord-309582-ihrj84hr	76	3	discontinuation	discontinuation	NN
cord-309582-ihrj84hr	76	4	of	of	IN
cord-309582-ihrj84hr	76	5	ongoing	ongoing	JJ
cord-309582-ihrj84hr	76	6	trials	trial	NNS
cord-309582-ihrj84hr	76	7	represents	represent	VBZ
cord-309582-ihrj84hr	76	8	a	a	DT
cord-309582-ihrj84hr	76	9	waste	waste	NN
cord-309582-ihrj84hr	76	10	of	of	IN
cord-309582-ihrj84hr	76	11	resources	resource	NNS
cord-309582-ihrj84hr	76	12	,	,	,
cord-309582-ihrj84hr	76	13	and	and	CC
cord-309582-ihrj84hr	76	14	of	of	IN
cord-309582-ihrj84hr	76	15	time	time	NN
cord-309582-ihrj84hr	76	16	and	and	CC
cord-309582-ihrj84hr	76	17	efforts	effort	NNS
cord-309582-ihrj84hr	76	18	of	of	IN
cord-309582-ihrj84hr	76	19	patients	patient	NNS
cord-309582-ihrj84hr	76	20	who	who	WP
cord-309582-ihrj84hr	76	21	have	have	VBP
cord-309582-ihrj84hr	76	22	completed	complete	VBN
cord-309582-ihrj84hr	76	23	the	the	DT
cord-309582-ihrj84hr	76	24	trial	trial	NN
cord-309582-ihrj84hr	76	25	as	as	RB
cord-309582-ihrj84hr	76	26	well	well	RB
cord-309582-ihrj84hr	76	27	as	as	IN
cord-309582-ihrj84hr	76	28	medical	medical	JJ
cord-309582-ihrj84hr	76	29	and	and	CC
cord-309582-ihrj84hr	76	30	research	research	NN
cord-309582-ihrj84hr	76	31	personal	personal	NN
cord-309582-ihrj84hr	76	32	involved	involve	VBN
cord-309582-ihrj84hr	76	33	in	in	IN
cord-309582-ihrj84hr	76	34	their	-PRON-	PRP$
cord-309582-ihrj84hr	76	35	design	design	NN
cord-309582-ihrj84hr	76	36	and	and	CC
cord-309582-ihrj84hr	76	37	implementation	implementation	NN
cord-309582-ihrj84hr	76	38	.	.	.
cord-309582-ihrj84hr	77	1	Supporting	support	VBG
cord-309582-ihrj84hr	77	2	the	the	DT
cord-309582-ihrj84hr	77	3	efforts	effort	NNS
cord-309582-ihrj84hr	77	4	to	to	TO
cord-309582-ihrj84hr	77	5	continue	continue	VB
cord-309582-ihrj84hr	77	6	ongoing	ongoing	JJ
cord-309582-ihrj84hr	77	7	clinical	clinical	JJ
cord-309582-ihrj84hr	77	8	trials	trial	NNS
cord-309582-ihrj84hr	77	9	and	and	CC
cord-309582-ihrj84hr	77	10	modifying	modify	VBG
cord-309582-ihrj84hr	77	11	them	-PRON-	PRP
cord-309582-ihrj84hr	77	12	,	,	,
cord-309582-ihrj84hr	77	13	if	if	IN
cord-309582-ihrj84hr	77	14	necessary	necessary	JJ
cord-309582-ihrj84hr	77	15	,	,	,
cord-309582-ihrj84hr	77	16	is	be	VBZ
cord-309582-ihrj84hr	77	17	thus	thus	RB
cord-309582-ihrj84hr	77	18	essential	essential	JJ
cord-309582-ihrj84hr	77	19	.	.	.
cord-309582-ihrj84hr	78	1	The	the	DT
cord-309582-ihrj84hr	78	2	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	78	3	pandemic	pandemic	NN
cord-309582-ihrj84hr	78	4	poses	pose	VBZ
cord-309582-ihrj84hr	78	5	significant	significant	JJ
cord-309582-ihrj84hr	78	6	challenges	challenge	NNS
cord-309582-ihrj84hr	78	7	for	for	IN
cord-309582-ihrj84hr	78	8	many	many	JJ
cord-309582-ihrj84hr	78	9	ongoing	ongoing	JJ
cord-309582-ihrj84hr	78	10	clinical	clinical	JJ
cord-309582-ihrj84hr	78	11	research	research	NN
cord-309582-ihrj84hr	78	12	trials	trial	NNS
cord-309582-ihrj84hr	78	13	because	because	IN
cord-309582-ihrj84hr	78	14	of	of	IN
cord-309582-ihrj84hr	78	15	additional	additional	JJ
cord-309582-ihrj84hr	78	16	challenges	challenge	NNS
cord-309582-ihrj84hr	78	17	.	.	.
cord-309582-ihrj84hr	79	1	Indeed	indeed	RB
cord-309582-ihrj84hr	79	2	,	,	,
cord-309582-ihrj84hr	79	3	examples	example	NNS
cord-309582-ihrj84hr	79	4	of	of	IN
cord-309582-ihrj84hr	79	5	barriers	barrier	NNS
cord-309582-ihrj84hr	79	6	faced	face	VBN
cord-309582-ihrj84hr	79	7	by	by	IN
cord-309582-ihrj84hr	79	8	sponsors	sponsor	NNS
cord-309582-ihrj84hr	79	9	and	and	CC
cord-309582-ihrj84hr	79	10	investigators	investigator	NNS
cord-309582-ihrj84hr	79	11	include	include	VBP
cord-309582-ihrj84hr	79	12	interruptions	interruption	NNS
cord-309582-ihrj84hr	79	13	to	to	IN
cord-309582-ihrj84hr	79	14	the	the	DT
cord-309582-ihrj84hr	79	15	supply	supply	NN
cord-309582-ihrj84hr	79	16	chains	chain	NNS
cord-309582-ihrj84hr	79	17	for	for	IN
cord-309582-ihrj84hr	79	18	the	the	DT
cord-309582-ihrj84hr	79	19	investigational	investigational	JJ
cord-309582-ihrj84hr	79	20	products	product	NNS
cord-309582-ihrj84hr	79	21	if	if	IN
cord-309582-ihrj84hr	79	22	applicable	applicable	JJ
cord-309582-ihrj84hr	79	23	,	,	,
cord-309582-ihrj84hr	79	24	the	the	DT
cord-309582-ihrj84hr	79	25	inability	inability	NN
cord-309582-ihrj84hr	79	26	of	of	IN
cord-309582-ihrj84hr	79	27	trials	trial	NNS
cord-309582-ihrj84hr	79	28	personnel	personnel	NNS
cord-309582-ihrj84hr	79	29	to	to	TO
cord-309582-ihrj84hr	79	30	perform	perform	VB
cord-309582-ihrj84hr	79	31	visits	visit	NNS
cord-309582-ihrj84hr	79	32	and/or	and/or	CC
cord-309582-ihrj84hr	79	33	laboratory	laboratory	NN
cord-309582-ihrj84hr	79	34	or	or	CC
cord-309582-ihrj84hr	79	35	imaging	imaging	NN
cord-309582-ihrj84hr	79	36	tests	test	NNS
cord-309582-ihrj84hr	79	37	on	on	IN
cord-309582-ihrj84hr	79	38	enrolled	enrol	VBN
cord-309582-ihrj84hr	79	39	patients	patient	NNS
cord-309582-ihrj84hr	79	40	,	,	,
cord-309582-ihrj84hr	79	41	data	datum	NNS
cord-309582-ihrj84hr	79	42	entry	entry	NN
cord-309582-ihrj84hr	79	43	,	,	,
cord-309582-ihrj84hr	79	44	serious	serious	JJ
cord-309582-ihrj84hr	79	45	adverse	adverse	JJ
cord-309582-ihrj84hr	79	46	events	event	NNS
cord-309582-ihrj84hr	79	47	notification	notification	NN
cord-309582-ihrj84hr	79	48	,	,	,
cord-309582-ihrj84hr	79	49	and	and	CC
cord-309582-ihrj84hr	79	50	more	more	RBR
cord-309582-ihrj84hr	79	51	generally	generally	RB
cord-309582-ihrj84hr	79	52	follow	follow	VBP
cord-309582-ihrj84hr	79	53	various	various	JJ
cord-309582-ihrj84hr	79	54	additional	additional	JJ
cord-309582-ihrj84hr	79	55	aspects	aspect	NNS
cord-309582-ihrj84hr	79	56	of	of	IN
cord-309582-ihrj84hr	79	57	published	publish	VBN
cord-309582-ihrj84hr	79	58	trials	trial	NNS
cord-309582-ihrj84hr	79	59	protocols	protocol	NNS
cord-309582-ihrj84hr	79	60	.	.	.
cord-309582-ihrj84hr	80	1	Due	due	IN
cord-309582-ihrj84hr	80	2	to	to	IN
cord-309582-ihrj84hr	80	3	above	above	IN
cord-309582-ihrj84hr	80	4	constrains	constrain	NNS
cord-309582-ihrj84hr	80	5	,	,	,
cord-309582-ihrj84hr	80	6	as	as	IN
cord-309582-ihrj84hr	80	7	a	a	DT
cord-309582-ihrj84hr	80	8	result	result	NN
cord-309582-ihrj84hr	80	9	,	,	,
cord-309582-ihrj84hr	80	10	a	a	DT
cord-309582-ihrj84hr	80	11	series	series	NN
cord-309582-ihrj84hr	80	12	of	of	IN
cord-309582-ihrj84hr	80	13	measures	measure	NNS
cord-309582-ihrj84hr	80	14	need	need	VBP
cord-309582-ihrj84hr	80	15	to	to	TO
cord-309582-ihrj84hr	80	16	be	be	VB
cord-309582-ihrj84hr	80	17	instituted	institute	VBN
cord-309582-ihrj84hr	80	18	,	,	,
cord-309582-ihrj84hr	80	19	ensuring	ensure	VBG
cord-309582-ihrj84hr	80	20	the	the	DT
cord-309582-ihrj84hr	80	21	rights	right	NNS
cord-309582-ihrj84hr	80	22	,	,	,
cord-309582-ihrj84hr	80	23	safety	safety	NN
cord-309582-ihrj84hr	80	24	,	,	,
cord-309582-ihrj84hr	80	25	and	and	CC
cord-309582-ihrj84hr	80	26	wellbeing	wellbeing	NN
cord-309582-ihrj84hr	80	27	of	of	IN
cord-309582-ihrj84hr	80	28	participants	participant	NNS
cord-309582-ihrj84hr	80	29	as	as	RB
cord-309582-ihrj84hr	80	30	well	well	RB
cord-309582-ihrj84hr	80	31	as	as	IN
cord-309582-ihrj84hr	80	32	the	the	DT
cord-309582-ihrj84hr	80	33	medical	medical	JJ
cord-309582-ihrj84hr	80	34	staff	staff	NN
cord-309582-ihrj84hr	80	35	involved	involve	VBN
cord-309582-ihrj84hr	80	36	in	in	IN
cord-309582-ihrj84hr	80	37	the	the	DT
cord-309582-ihrj84hr	80	38	conduction	conduction	NN
cord-309582-ihrj84hr	80	39	of	of	IN
cord-309582-ihrj84hr	80	40	clinical	clinical	JJ
cord-309582-ihrj84hr	80	41	trials	trial	NNS
cord-309582-ihrj84hr	80	42	.	.	.
cord-309582-ihrj84hr	81	1	Both	both	DT
cord-309582-ihrj84hr	81	2	sponsors	sponsor	NNS
cord-309582-ihrj84hr	81	3	and	and	CC
cord-309582-ihrj84hr	81	4	investigators	investigator	NNS
cord-309582-ihrj84hr	81	5	must	must	MD
cord-309582-ihrj84hr	81	6	understand	understand	VB
cord-309582-ihrj84hr	81	7	the	the	DT
cord-309582-ihrj84hr	81	8	critical	critical	JJ
cord-309582-ihrj84hr	81	9	situation	situation	NN
cord-309582-ihrj84hr	81	10	faced	face	VBN
cord-309582-ihrj84hr	81	11	by	by	IN
cord-309582-ihrj84hr	81	12	the	the	DT
cord-309582-ihrj84hr	81	13	medical	medical	JJ
cord-309582-ihrj84hr	81	14	authorities	authority	NNS
cord-309582-ihrj84hr	81	15	around	around	IN
cord-309582-ihrj84hr	81	16	the	the	DT
cord-309582-ihrj84hr	81	17	globe	globe	NN
cord-309582-ihrj84hr	81	18	.	.	.
cord-309582-ihrj84hr	82	1	Fairness	fairness	NN
cord-309582-ihrj84hr	82	2	is	be	VBZ
cord-309582-ihrj84hr	82	3	thus	thus	RB
cord-309582-ihrj84hr	82	4	a	a	DT
cord-309582-ihrj84hr	82	5	better	well	JJR
cord-309582-ihrj84hr	82	6	way	way	NN
cord-309582-ihrj84hr	82	7	of	of	IN
cord-309582-ihrj84hr	82	8	approaching	approach	VBG
cord-309582-ihrj84hr	82	9	the	the	DT
cord-309582-ihrj84hr	82	10	ethical	ethical	JJ
cord-309582-ihrj84hr	82	11	issues	issue	NNS
cord-309582-ihrj84hr	82	12	faced	face	VBN
cord-309582-ihrj84hr	82	13	by	by	IN
cord-309582-ihrj84hr	82	14	clinical	clinical	JJ
cord-309582-ihrj84hr	82	15	trial	trial	NN
cord-309582-ihrj84hr	82	16	staff	staff	NN
cord-309582-ihrj84hr	82	17	and	and	CC
cord-309582-ihrj84hr	82	18	regulatory	regulatory	JJ
cord-309582-ihrj84hr	82	19	agencies	agency	NNS
cord-309582-ihrj84hr	82	20	during	during	IN
cord-309582-ihrj84hr	82	21	this	this	DT
cord-309582-ihrj84hr	82	22	pandemic	pandemic	NN
cord-309582-ihrj84hr	82	23	.	.	.
cord-309582-ihrj84hr	83	1	Fairness	fairness	NN
cord-309582-ihrj84hr	83	2	refers	refer	VBZ
cord-309582-ihrj84hr	83	3	to	to	IN
cord-309582-ihrj84hr	83	4	the	the	DT
cord-309582-ihrj84hr	83	5	equitable	equitable	JJ
cord-309582-ihrj84hr	83	6	distribution	distribution	NN
cord-309582-ihrj84hr	83	7	of	of	IN
cord-309582-ihrj84hr	83	8	benefits	benefit	NNS
cord-309582-ihrj84hr	83	9	.	.	.
cord-309582-ihrj84hr	84	1	It	-PRON-	PRP
cord-309582-ihrj84hr	84	2	is	be	VBZ
cord-309582-ihrj84hr	84	3	about	about	IN
cord-309582-ihrj84hr	84	4	meeting	meet	VBG
cord-309582-ihrj84hr	84	5	everyone	everyone	NN
cord-309582-ihrj84hr	84	6	's	's	POS
cord-309582-ihrj84hr	84	7	individual	individual	JJ
cord-309582-ihrj84hr	84	8	needs	need	NNS
cord-309582-ihrj84hr	84	9	;	;	:
cord-309582-ihrj84hr	84	10	therefore	therefore	RB
cord-309582-ihrj84hr	84	11	cultural	cultural	JJ
cord-309582-ihrj84hr	84	12	,	,	,
cord-309582-ihrj84hr	84	13	racial	racial	JJ
cord-309582-ihrj84hr	84	14	,	,	,
cord-309582-ihrj84hr	84	15	social	social	JJ
cord-309582-ihrj84hr	84	16	or	or	CC
cord-309582-ihrj84hr	84	17	other	other	JJ
cord-309582-ihrj84hr	84	18	biases	bias	NNS
cord-309582-ihrj84hr	84	19	must	must	MD
cord-309582-ihrj84hr	84	20	be	be	VB
cord-309582-ihrj84hr	84	21	avoided	avoid	VBN
cord-309582-ihrj84hr	84	22	.	.	.
cord-309582-ihrj84hr	85	1	In	in	IN
cord-309582-ihrj84hr	85	2	addition	addition	NN
cord-309582-ihrj84hr	85	3	,	,	,
cord-309582-ihrj84hr	85	4	clinical	clinical	JJ
cord-309582-ihrj84hr	85	5	trials	trial	NNS
cord-309582-ihrj84hr	85	6	sponsors	sponsor	NNS
cord-309582-ihrj84hr	85	7	as	as	RB
cord-309582-ihrj84hr	85	8	well	well	RB
cord-309582-ihrj84hr	85	9	as	as	IN
cord-309582-ihrj84hr	85	10	investigators	investigator	NNS
cord-309582-ihrj84hr	85	11	must	must	MD
cord-309582-ihrj84hr	85	12	uphold	uphold	VB
cord-309582-ihrj84hr	85	13	the	the	DT
cord-309582-ihrj84hr	85	14	spirit	spirit	NN
cord-309582-ihrj84hr	85	15	of	of	IN
cord-309582-ihrj84hr	85	16	existing	exist	VBG
cord-309582-ihrj84hr	85	17	laws	law	NNS
cord-309582-ihrj84hr	85	18	while	while	IN
cord-309582-ihrj84hr	85	19	remaining	remain	VBG
cord-309582-ihrj84hr	85	20	fair	fair	JJ
cord-309582-ihrj84hr	85	21	to	to	IN
cord-309582-ihrj84hr	85	22	all	all	DT
cord-309582-ihrj84hr	85	23	individuals	individual	NNS
cord-309582-ihrj84hr	85	24	involved	involve	VBN
cord-309582-ihrj84hr	85	25	in	in	IN
cord-309582-ihrj84hr	85	26	the	the	DT
cord-309582-ihrj84hr	85	27	clinical	clinical	JJ
cord-309582-ihrj84hr	85	28	trials	trial	NNS
cord-309582-ihrj84hr	85	29	[	[	-LRB-
cord-309582-ihrj84hr	85	30	20	20	CD
cord-309582-ihrj84hr	85	31	]	]	-RRB-
cord-309582-ihrj84hr	85	32	.	.	.
cord-309582-ihrj84hr	86	1	Clinical	clinical	JJ
cord-309582-ihrj84hr	86	2	trial	trial	NN
cord-309582-ihrj84hr	86	3	sponsors	sponsor	NNS
cord-309582-ihrj84hr	86	4	and	and	CC
cord-309582-ihrj84hr	86	5	investigators	investigator	NNS
cord-309582-ihrj84hr	86	6	must	must	MD
cord-309582-ihrj84hr	86	7	decide	decide	VB
cord-309582-ihrj84hr	86	8	whether	whether	IN
cord-309582-ihrj84hr	86	9	trial	trial	NN
cord-309582-ihrj84hr	86	10	subject	subject	JJ
cord-309582-ihrj84hr	86	11	safety	safety	NN
cord-309582-ihrj84hr	86	12	considerations	consideration	NNS
cord-309582-ihrj84hr	86	13	allow	allow	VBP
cord-309582-ihrj84hr	86	14	continuation	continuation	NN
cord-309582-ihrj84hr	86	15	of	of	IN
cord-309582-ihrj84hr	86	16	the	the	DT
cord-309582-ihrj84hr	86	17	protocols	protocol	NNS
cord-309582-ihrj84hr	86	18	,	,	,
cord-309582-ihrj84hr	86	19	or	or	CC
cord-309582-ihrj84hr	86	20	rather	rather	RB
cord-309582-ihrj84hr	86	21	temporarily	temporarily	RB
cord-309582-ihrj84hr	86	22	halting	halt	VBG
cord-309582-ihrj84hr	86	23	administration	administration	NN
cord-309582-ihrj84hr	86	24	of	of	IN
cord-309582-ihrj84hr	86	25	the	the	DT
cord-309582-ihrj84hr	86	26	interventional	interventional	JJ
cord-309582-ihrj84hr	86	27	productor	productor	NNP
cord-309582-ihrj84hr	86	28	patient	patient	NN
cord-309582-ihrj84hr	86	29	recruitment	recruitment	NN
cord-309582-ihrj84hr	86	30	.	.	.
cord-309582-ihrj84hr	87	1	Many	many	JJ
cord-309582-ihrj84hr	87	2	research	research	NN
cord-309582-ihrj84hr	87	3	regulatory	regulatory	JJ
cord-309582-ihrj84hr	87	4	authorities	authority	NNS
cord-309582-ihrj84hr	87	5	such	such	JJ
cord-309582-ihrj84hr	87	6	as	as	IN
cord-309582-ihrj84hr	87	7	the	the	DT
cord-309582-ihrj84hr	87	8	United	United	NNP
cord-309582-ihrj84hr	87	9	States	States	NNP
cord-309582-ihrj84hr	87	10	Food	Food	NNP
cord-309582-ihrj84hr	87	11	and	and	CC
cord-309582-ihrj84hr	87	12	Drug	Drug	NNP
cord-309582-ihrj84hr	87	13	Administration	Administration	NNP
cord-309582-ihrj84hr	87	14	and	and	CC
cord-309582-ihrj84hr	87	15	the	the	DT
cord-309582-ihrj84hr	87	16	Clinical	Clinical	NNP
cord-309582-ihrj84hr	87	17	Trials	Trials	NNPS
cord-309582-ihrj84hr	87	18	Expert	Expert	NNP
cord-309582-ihrj84hr	87	19	Group	Group	NNP
cord-309582-ihrj84hr	87	20	at	at	IN
cord-309582-ihrj84hr	87	21	the	the	DT
cord-309582-ihrj84hr	87	22	European	European	NNP
cord-309582-ihrj84hr	87	23	Medicines	Medicines	NNPS
cord-309582-ihrj84hr	87	24	Agency	Agency	NNP
cord-309582-ihrj84hr	87	25	have	have	VBP
cord-309582-ihrj84hr	87	26	published	publish	VBN
cord-309582-ihrj84hr	87	27	statements	statement	NNS
cord-309582-ihrj84hr	87	28	to	to	TO
cord-309582-ihrj84hr	87	29	regulate	regulate	VB
cord-309582-ihrj84hr	87	30	medical	medical	JJ
cord-309582-ihrj84hr	87	31	research	research	NN
cord-309582-ihrj84hr	87	32	during	during	IN
cord-309582-ihrj84hr	87	33	the	the	DT
cord-309582-ihrj84hr	87	34	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	87	35	pandemic	pandemic	NN
cord-309582-ihrj84hr	87	36	in	in	IN
cord-309582-ihrj84hr	87	37	order	order	NN
cord-309582-ihrj84hr	87	38	to	to	TO
cord-309582-ihrj84hr	87	39	ensure	ensure	VB
cord-309582-ihrj84hr	87	40	the	the	DT
cord-309582-ihrj84hr	87	41	safeguard	safeguard	NN
cord-309582-ihrj84hr	87	42	and	and	CC
cord-309582-ihrj84hr	87	43	preservation	preservation	NN
cord-309582-ihrj84hr	87	44	of	of	IN
cord-309582-ihrj84hr	87	45	rights	right	NNS
cord-309582-ihrj84hr	87	46	of	of	IN
cord-309582-ihrj84hr	87	47	patients	patient	NNS
cord-309582-ihrj84hr	87	48	,	,	,
cord-309582-ihrj84hr	87	49	medical	medical	JJ
cord-309582-ihrj84hr	87	50	staff	staff	NN
cord-309582-ihrj84hr	87	51	and	and	CC
cord-309582-ihrj84hr	87	52	personnel	personnel	NNS
cord-309582-ihrj84hr	87	53	involved	involve	VBN
cord-309582-ihrj84hr	87	54	in	in	IN
cord-309582-ihrj84hr	87	55	conducting	conduct	VBG
cord-309582-ihrj84hr	87	56	,	,	,
cord-309582-ihrj84hr	87	57	monitoring	monitoring	NN
cord-309582-ihrj84hr	87	58	and	and	CC
cord-309582-ihrj84hr	87	59	the	the	DT
cord-309582-ihrj84hr	87	60	follow	follow	VB
cord-309582-ihrj84hr	87	61	-	-	HYPH
cord-309582-ihrj84hr	87	62	up	up	RP
cord-309582-ihrj84hr	87	63	data	data	NN
cord-309582-ihrj84hr	87	64	collection	collection	NN
cord-309582-ihrj84hr	87	65	and	and	CC
cord-309582-ihrj84hr	87	66	analysis	analysis	NN
cord-309582-ihrj84hr	87	67	of	of	IN
cord-309582-ihrj84hr	87	68	clinical	clinical	JJ
cord-309582-ihrj84hr	87	69	trials	trial	NNS
cord-309582-ihrj84hr	87	70	[	[	-LRB-
cord-309582-ihrj84hr	87	71	21	21	CD
cord-309582-ihrj84hr	87	72	,	,	,
cord-309582-ihrj84hr	87	73	22	22	CD
cord-309582-ihrj84hr	87	74	]	]	-RRB-
cord-309582-ihrj84hr	87	75	.	.	.
cord-309582-ihrj84hr	88	1	Local	Local	NNP
cord-309582-ihrj84hr	88	2	Institutional	Institutional	NNP
cord-309582-ihrj84hr	88	3	Review	Review	NNP
cord-309582-ihrj84hr	88	4	Boards	Boards	NNP
cord-309582-ihrj84hr	88	5	(	(	-LRB-
cord-309582-ihrj84hr	88	6	IRBs	irb	NNS
cord-309582-ihrj84hr	88	7	)	)	-RRB-
cord-309582-ihrj84hr	88	8	are	be	VBP
cord-309582-ihrj84hr	88	9	also	also	RB
cord-309582-ihrj84hr	88	10	encouraged	encourage	VBN
cord-309582-ihrj84hr	88	11	to	to	TO
cord-309582-ihrj84hr	88	12	revise	revise	VB
cord-309582-ihrj84hr	88	13	and	and	CC
cord-309582-ihrj84hr	88	14	modify	modify	VB
cord-309582-ihrj84hr	88	15	their	-PRON-	PRP$
cord-309582-ihrj84hr	88	16	policies	policy	NNS
cord-309582-ihrj84hr	88	17	and	and	CC
cord-309582-ihrj84hr	88	18	procedures	procedure	NNS
cord-309582-ihrj84hr	88	19	to	to	TO
cord-309582-ihrj84hr	88	20	adapt	adapt	VB
cord-309582-ihrj84hr	88	21	to	to	IN
cord-309582-ihrj84hr	88	22	the	the	DT
cord-309582-ihrj84hr	88	23	current	current	JJ
cord-309582-ihrj84hr	88	24	situation	situation	NN
cord-309582-ihrj84hr	88	25	without	without	IN
cord-309582-ihrj84hr	88	26	compromising	compromise	VBG
cord-309582-ihrj84hr	88	27	patient	patient	JJ
cord-309582-ihrj84hr	88	28	care	care	NN
cord-309582-ihrj84hr	88	29	while	while	IN
cord-309582-ihrj84hr	88	30	ensuring	ensure	VBG
cord-309582-ihrj84hr	88	31	the	the	DT
cord-309582-ihrj84hr	88	32	safety	safety	NN
cord-309582-ihrj84hr	88	33	of	of	IN
cord-309582-ihrj84hr	88	34	all	all	DT
cord-309582-ihrj84hr	88	35	personnel	personnel	NNS
cord-309582-ihrj84hr	88	36	involved	involve	VBN
cord-309582-ihrj84hr	88	37	in	in	IN
cord-309582-ihrj84hr	88	38	clinical	clinical	JJ
cord-309582-ihrj84hr	88	39	trials	trial	NNS
cord-309582-ihrj84hr	88	40	.	.	.
cord-309582-ihrj84hr	89	1	Additional	additional	JJ
cord-309582-ihrj84hr	89	2	extensions	extension	NNS
cord-309582-ihrj84hr	89	3	to	to	TO
cord-309582-ihrj84hr	89	4	study	study	VB
cord-309582-ihrj84hr	89	5	periods	period	NNS
cord-309582-ihrj84hr	89	6	beyond	beyond	IN
cord-309582-ihrj84hr	89	7	those	those	DT
cord-309582-ihrj84hr	89	8	already	already	RB
cord-309582-ihrj84hr	89	9	provided	provide	VBN
cord-309582-ihrj84hr	89	10	by	by	IN
cord-309582-ihrj84hr	89	11	local	local	JJ
cord-309582-ihrj84hr	89	12	IRBs	irb	NNS
cord-309582-ihrj84hr	89	13	must	must	MD
cord-309582-ihrj84hr	89	14	be	be	VB
cord-309582-ihrj84hr	89	15	allowed	allow	VBN
cord-309582-ihrj84hr	89	16	in	in	IN
cord-309582-ihrj84hr	89	17	order	order	NN
cord-309582-ihrj84hr	89	18	to	to	TO
cord-309582-ihrj84hr	89	19	accommodate	accommodate	VB
cord-309582-ihrj84hr	89	20	for	for	IN
cord-309582-ihrj84hr	89	21	the	the	DT
cord-309582-ihrj84hr	89	22	unpredictable	unpredictable	JJ
cord-309582-ihrj84hr	89	23	study	study	NN
cord-309582-ihrj84hr	89	24	operational	operational	JJ
cord-309582-ihrj84hr	89	25	time	time	NN
cord-309582-ihrj84hr	89	26	lost	lose	VBN
cord-309582-ihrj84hr	89	27	during	during	IN
cord-309582-ihrj84hr	89	28	this	this	DT
cord-309582-ihrj84hr	89	29	COVID-19	covid-19	CD
cord-309582-ihrj84hr	89	30	pandemic	pandemic	NN
cord-309582-ihrj84hr	89	31	.	.	.
cord-309582-ihrj84hr	90	1	Adopted	adopt	VBN
cord-309582-ihrj84hr	90	2	modifications	modification	NNS
cord-309582-ihrj84hr	90	3	must	must	MD
cord-309582-ihrj84hr	90	4	not	not	RB
cord-309582-ihrj84hr	90	5	compromise	compromise	VB
cord-309582-ihrj84hr	90	6	the	the	DT
cord-309582-ihrj84hr	90	7	integrity	integrity	NN
cord-309582-ihrj84hr	90	8	of	of	IN
cord-309582-ihrj84hr	90	9	the	the	DT
cord-309582-ihrj84hr	90	10	study	study	NN
cord-309582-ihrj84hr	90	11	methodology	methodology	NN
cord-309582-ihrj84hr	90	12	while	while	IN
cord-309582-ihrj84hr	90	13	the	the	DT
cord-309582-ihrj84hr	90	14	trial	trial	NN
cord-309582-ihrj84hr	90	15	must	must	MD
cord-309582-ihrj84hr	90	16	continue	continue	VB
cord-309582-ihrj84hr	90	17	to	to	TO
cord-309582-ihrj84hr	90	18	be	be	VB
cord-309582-ihrj84hr	90	19	conducted	conduct	VBN
cord-309582-ihrj84hr	90	20	in	in	IN
cord-309582-ihrj84hr	90	21	accordance	accordance	NN
cord-309582-ihrj84hr	90	22	with	with	IN
cord-309582-ihrj84hr	90	23	Good	Good	NNP
cord-309582-ihrj84hr	90	24	August	August	NNP
cord-309582-ihrj84hr	90	25	6	6	CD
cord-309582-ihrj84hr	90	26	,	,	,
cord-309582-ihrj84hr	90	27	2020	2020	CD
cord-309582-ihrj84hr	90	28	Volume	volume	NN
cord-309582-ihrj84hr	90	29	8	8	CD
cord-309582-ihrj84hr	90	30	Issue	issue	NN
cord-309582-ihrj84hr	90	31	15	15	CD
cord-309582-ihrj84hr	90	32	Clinical	Clinical	NNP
cord-309582-ihrj84hr	90	33	Practices	Practices	NNPS
cord-309582-ihrj84hr	90	34	and	and	CC
cord-309582-ihrj84hr	90	35	comply	comply	VB
cord-309582-ihrj84hr	90	36	with	with	IN
cord-309582-ihrj84hr	90	37	local	local	JJ
cord-309582-ihrj84hr	90	38	and	and	CC
cord-309582-ihrj84hr	90	39	national	national	JJ
cord-309582-ihrj84hr	90	40	regulatory	regulatory	JJ
cord-309582-ihrj84hr	90	41	requirements	requirement	NNS
cord-309582-ihrj84hr	90	42	.	.	.
cord-309582-ihrj84hr	91	1	Modifications	modification	NNS
cord-309582-ihrj84hr	91	2	of	of	IN
cord-309582-ihrj84hr	91	3	protocols	protocol	NNS
cord-309582-ihrj84hr	91	4	such	such	JJ
cord-309582-ihrj84hr	91	5	as	as	IN
cord-309582-ihrj84hr	91	6	delaying	delay	VBG
cord-309582-ihrj84hr	91	7	recruitment	recruitment	NN
cord-309582-ihrj84hr	91	8	of	of	IN
cord-309582-ihrj84hr	91	9	patients	patient	NNS
cord-309582-ihrj84hr	91	10	,	,	,
cord-309582-ihrj84hr	91	11	postponing	postpone	VBG
cord-309582-ihrj84hr	91	12	certain	certain	JJ
cord-309582-ihrj84hr	91	13	assessments	assessment	NNS
cord-309582-ihrj84hr	91	14	and	and	CC
cord-309582-ihrj84hr	91	15	monitoring	monitor	VBG
cord-309582-ihrj84hr	91	16	subjects	subject	NNS
cord-309582-ihrj84hr	91	17	through	through	IN
cord-309582-ihrj84hr	91	18	phone	phone	NN
cord-309582-ihrj84hr	91	19	calls	call	NNS
cord-309582-ihrj84hr	91	20	or	or	CC
cord-309582-ihrj84hr	91	21	virtual	virtual	JJ
cord-309582-ihrj84hr	91	22	visits	visit	NNS
cord-309582-ihrj84hr	91	23	,	,	,
cord-309582-ihrj84hr	91	24	limiting	limit	VBG
cord-309582-ihrj84hr	91	25	study	study	NN
cord-309582-ihrj84hr	91	26	visits	visit	NNS
cord-309582-ihrj84hr	91	27	,	,	,
cord-309582-ihrj84hr	91	28	and	and	CC
cord-309582-ihrj84hr	91	29	preventing	prevent	VBG
cord-309582-ihrj84hr	91	30	large	large	JJ
cord-309582-ihrj84hr	91	31	gathering	gathering	NN
cord-309582-ihrj84hr	91	32	of	of	IN
cord-309582-ihrj84hr	91	33	study	study	NN
cord-309582-ihrj84hr	91	34	subjects	subject	NNS
cord-309582-ihrj84hr	91	35	as	as	RB
cord-309582-ihrj84hr	91	36	well	well	RB
cord-309582-ihrj84hr	91	37	as	as	IN
cord-309582-ihrj84hr	91	38	permitting	permit	VBG
cord-309582-ihrj84hr	91	39	certain	certain	JJ
cord-309582-ihrj84hr	91	40	tests	test	NNS
cord-309582-ihrj84hr	91	41	to	to	TO
cord-309582-ihrj84hr	91	42	be	be	VB
cord-309582-ihrj84hr	91	43	done	do	VBN
cord-309582-ihrj84hr	91	44	in	in	IN
cord-309582-ihrj84hr	91	45	nearby	nearby	JJ
cord-309582-ihrj84hr	91	46	clinics	clinic	NNS
cord-309582-ihrj84hr	91	47	rather	rather	RB
cord-309582-ihrj84hr	91	48	than	than	IN
cord-309582-ihrj84hr	91	49	centrally	centrally	RB
cord-309582-ihrj84hr	91	50	,	,	,
cord-309582-ihrj84hr	91	51	where	where	WRB
cord-309582-ihrj84hr	91	52	appropriate	appropriate	JJ
cord-309582-ihrj84hr	91	53	,	,	,
cord-309582-ihrj84hr	91	54	will	will	MD
cord-309582-ihrj84hr	91	55	most	most	RBS
cord-309582-ihrj84hr	91	56	likely	likely	RB
cord-309582-ihrj84hr	91	57	ensure	ensure	VB
cord-309582-ihrj84hr	91	58	patient	patient	JJ
cord-309582-ihrj84hr	91	59	and	and	CC
cord-309582-ihrj84hr	91	60	medical	medical	JJ
cord-309582-ihrj84hr	91	61	staff	staff	NN
cord-309582-ihrj84hr	91	62	safety	safety	NN
cord-309582-ihrj84hr	91	63	without	without	IN
cord-309582-ihrj84hr	91	64	compromising	compromise	VBG
cord-309582-ihrj84hr	91	65	progression	progression	NN
cord-309582-ihrj84hr	91	66	of	of	IN
cord-309582-ihrj84hr	91	67	the	the	DT
cord-309582-ihrj84hr	91	68	trials	trial	NNS
cord-309582-ihrj84hr	91	69	.	.	.
cord-309582-ihrj84hr	92	1	Sponsors	sponsor	NNS
cord-309582-ihrj84hr	92	2	as	as	RB
cord-309582-ihrj84hr	92	3	well	well	RB
cord-309582-ihrj84hr	92	4	as	as	IN
cord-309582-ihrj84hr	92	5	investigators	investigator	NNS
cord-309582-ihrj84hr	92	6	should	should	MD
cord-309582-ihrj84hr	92	7	develop	develop	VB
cord-309582-ihrj84hr	92	8	a	a	DT
cord-309582-ihrj84hr	92	9	process	process	NN
cord-309582-ihrj84hr	92	10	to	to	TO
cord-309582-ihrj84hr	92	11	identify	identify	VB
cord-309582-ihrj84hr	92	12	,	,	,
cord-309582-ihrj84hr	92	13	document	document	NN
cord-309582-ihrj84hr	92	14	,	,	,
cord-309582-ihrj84hr	92	15	assess	assess	VB
cord-309582-ihrj84hr	92	16	and	and	CC
cord-309582-ihrj84hr	92	17	report	report	VB
cord-309582-ihrj84hr	92	18	all	all	DT
cord-309582-ihrj84hr	92	19	protocol	protocol	NN
cord-309582-ihrj84hr	92	20	deviations	deviation	NNS
cord-309582-ihrj84hr	92	21	to	to	IN
cord-309582-ihrj84hr	92	22	the	the	DT
cord-309582-ihrj84hr	92	23	sponsor	sponsor	NN
cord-309582-ihrj84hr	92	24	and	and	CC
cord-309582-ihrj84hr	92	25	local	local	JJ
cord-309582-ihrj84hr	92	26	IRBs	irb	NNS
cord-309582-ihrj84hr	92	27	.	.	.
cord-309582-ihrj84hr	93	1	These	these	DT
cord-309582-ihrj84hr	93	2	protocol	protocol	NN
cord-309582-ihrj84hr	93	3	deviations	deviation	NNS
cord-309582-ihrj84hr	93	4	must	must	MD
cord-309582-ihrj84hr	93	5	also	also	RB
cord-309582-ihrj84hr	93	6	be	be	VB
cord-309582-ihrj84hr	93	7	documented	document	VBN
cord-309582-ihrj84hr	93	8	to	to	TO
cord-309582-ihrj84hr	93	9	better	well	RBR
cord-309582-ihrj84hr	93	10	complete	complete	VB
cord-309582-ihrj84hr	93	11	and	and	CC
cord-309582-ihrj84hr	93	12	interpret	interpret	VB
cord-309582-ihrj84hr	93	13	subsequent	subsequent	JJ
cord-309582-ihrj84hr	93	14	analyses	analysis	NNS
cord-309582-ihrj84hr	93	15	of	of	IN
cord-309582-ihrj84hr	93	16	the	the	DT
cord-309582-ihrj84hr	93	17	study	study	NN
cord-309582-ihrj84hr	93	18	findings	finding	NNS
cord-309582-ihrj84hr	93	19	.	.	.
cord-309582-ihrj84hr	94	1	As	as	IN
cord-309582-ihrj84hr	94	2	it	-PRON-	PRP
cord-309582-ihrj84hr	94	3	is	be	VBZ
cord-309582-ihrj84hr	94	4	not	not	RB
cord-309582-ihrj84hr	94	5	clear	clear	JJ
cord-309582-ihrj84hr	94	6	when	when	WRB
cord-309582-ihrj84hr	94	7	the	the	DT
cord-309582-ihrj84hr	94	8	pandemic	pandemic	NN
cord-309582-ihrj84hr	94	9	will	will	MD
cord-309582-ihrj84hr	94	10	end	end	VB
cord-309582-ihrj84hr	94	11	,	,	,
cord-309582-ihrj84hr	94	12	it	-PRON-	PRP
cord-309582-ihrj84hr	94	13	is	be	VBZ
cord-309582-ihrj84hr	94	14	important	important	JJ
cord-309582-ihrj84hr	94	15	that	that	IN
cord-309582-ihrj84hr	94	16	investigators	investigator	NNS
cord-309582-ihrj84hr	94	17	put	put	VBD
cord-309582-ihrj84hr	94	18	the	the	DT
cord-309582-ihrj84hr	94	19	aforementioned	aforementioned	JJ
cord-309582-ihrj84hr	94	20	strategies	strategy	NNS
cord-309582-ihrj84hr	94	21	into	into	IN
cord-309582-ihrj84hr	94	22	place	place	NN
cord-309582-ihrj84hr	94	23	for	for	IN
cord-309582-ihrj84hr	94	24	an	an	DT
cord-309582-ihrj84hr	94	25	adequate	adequate	JJ
cord-309582-ihrj84hr	94	26	period	period	NN
cord-309582-ihrj84hr	94	27	of	of	IN
cord-309582-ihrj84hr	94	28	time	time	NN
cord-309582-ihrj84hr	94	29	.	.	.
cord-309582-ihrj84hr	95	1	Medical	medical	JJ
cord-309582-ihrj84hr	95	2	research	research	NN
cord-309582-ihrj84hr	95	3	during	during	IN
cord-309582-ihrj84hr	95	4	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	95	5	pandemic	pandemic	NN
cord-309582-ihrj84hr	95	6	should	should	MD
cord-309582-ihrj84hr	95	7	focus	focus	VB
cord-309582-ihrj84hr	95	8	on	on	IN
cord-309582-ihrj84hr	95	9	the	the	DT
cord-309582-ihrj84hr	95	10	epidemiology	epidemiology	NN
cord-309582-ihrj84hr	95	11	of	of	IN
cord-309582-ihrj84hr	95	12	the	the	DT
cord-309582-ihrj84hr	95	13	SARS	SARS	NNP
cord-309582-ihrj84hr	95	14	-	-	HYPH
cord-309582-ihrj84hr	95	15	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	95	16	,	,	,
cord-309582-ihrj84hr	95	17	its	-PRON-	PRP$
cord-309582-ihrj84hr	95	18	modes	mode	NNS
cord-309582-ihrj84hr	95	19	of	of	IN
cord-309582-ihrj84hr	95	20	transmission	transmission	NN
cord-309582-ihrj84hr	95	21	,	,	,
cord-309582-ihrj84hr	95	22	COVID-19	covid-19	VB
cord-309582-ihrj84hr	95	23	clinical	clinical	JJ
cord-309582-ihrj84hr	95	24	presentations	presentation	NNS
cord-309582-ihrj84hr	95	25	,	,	,
cord-309582-ihrj84hr	95	26	effectiveness	effectiveness	NN
cord-309582-ihrj84hr	95	27	of	of	IN
cord-309582-ihrj84hr	95	28	preventative	preventative	JJ
cord-309582-ihrj84hr	95	29	measures	measure	NNS
cord-309582-ihrj84hr	95	30	and	and	CC
cord-309582-ihrj84hr	95	31	possible	possible	JJ
cord-309582-ihrj84hr	95	32	modalities	modality	NNS
cord-309582-ihrj84hr	95	33	of	of	IN
cord-309582-ihrj84hr	95	34	treatment	treatment	NN
cord-309582-ihrj84hr	95	35	.	.	.
cord-309582-ihrj84hr	96	1	Medical	medical	JJ
cord-309582-ihrj84hr	96	2	research	research	NN
cord-309582-ihrj84hr	96	3	must	must	MD
cord-309582-ihrj84hr	96	4	be	be	VB
cord-309582-ihrj84hr	96	5	time	time	NN
cord-309582-ihrj84hr	96	6	-	-	HYPH
cord-309582-ihrj84hr	96	7	efficient	efficient	JJ
cord-309582-ihrj84hr	96	8	and	and	CC
cord-309582-ihrj84hr	96	9	flexible	flexible	JJ
cord-309582-ihrj84hr	96	10	due	due	IN
cord-309582-ihrj84hr	96	11	to	to	IN
cord-309582-ihrj84hr	96	12	high	high	JJ
cord-309582-ihrj84hr	96	13	contagiousness	contagiousness	NN
cord-309582-ihrj84hr	96	14	of	of	IN
cord-309582-ihrj84hr	96	15	the	the	DT
cord-309582-ihrj84hr	96	16	SARS	SARS	NNP
cord-309582-ihrj84hr	96	17	-	-	HYPH
cord-309582-ihrj84hr	96	18	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	96	19	,	,	,
cord-309582-ihrj84hr	96	20	the	the	DT
cord-309582-ihrj84hr	96	21	large	large	JJ
cord-309582-ihrj84hr	96	22	number	number	NN
cord-309582-ihrj84hr	96	23	of	of	IN
cord-309582-ihrj84hr	96	24	reported	report	VBN
cord-309582-ihrj84hr	96	25	deaths	death	NNS
cord-309582-ihrj84hr	96	26	,	,	,
cord-309582-ihrj84hr	96	27	and	and	CC
cord-309582-ihrj84hr	96	28	time	time	NN
cord-309582-ihrj84hr	96	29	constraints	constraint	NNS
cord-309582-ihrj84hr	96	30	needed	need	VBN
cord-309582-ihrj84hr	96	31	to	to	TO
cord-309582-ihrj84hr	96	32	perform	perform	VB
cord-309582-ihrj84hr	96	33	high	high	JJ
cord-309582-ihrj84hr	96	34	quality	quality	NN
cord-309582-ihrj84hr	96	35	clinical	clinical	JJ
cord-309582-ihrj84hr	96	36	trials	trial	NNS
cord-309582-ihrj84hr	96	37	.	.	.
cord-309582-ihrj84hr	97	1	Regulatory	regulatory	JJ
cord-309582-ihrj84hr	97	2	processes	process	NNS
cord-309582-ihrj84hr	97	3	must	must	MD
cord-309582-ihrj84hr	97	4	facilitate	facilitate	VB
cord-309582-ihrj84hr	97	5	the	the	DT
cord-309582-ihrj84hr	97	6	generation	generation	NN
cord-309582-ihrj84hr	97	7	of	of	IN
cord-309582-ihrj84hr	97	8	data	datum	NNS
cord-309582-ihrj84hr	97	9	from	from	IN
cord-309582-ihrj84hr	97	10	observational	observational	JJ
cord-309582-ihrj84hr	97	11	studies	study	NNS
cord-309582-ihrj84hr	97	12	in	in	IN
cord-309582-ihrj84hr	97	13	real	real	JJ
cord-309582-ihrj84hr	97	14	world	world	NN
cord-309582-ihrj84hr	97	15	settings	setting	NNS
cord-309582-ihrj84hr	97	16	that	that	WDT
cord-309582-ihrj84hr	97	17	may	may	MD
cord-309582-ihrj84hr	97	18	be	be	VB
cord-309582-ihrj84hr	97	19	very	very	RB
cord-309582-ihrj84hr	97	20	important	important	JJ
cord-309582-ihrj84hr	97	21	in	in	IN
cord-309582-ihrj84hr	97	22	better	well	RBR
cord-309582-ihrj84hr	97	23	guiding	guide	VBG
cord-309582-ihrj84hr	97	24	the	the	DT
cord-309582-ihrj84hr	97	25	development	development	NN
cord-309582-ihrj84hr	97	26	of	of	IN
cord-309582-ihrj84hr	97	27	vaccines	vaccine	NNS
cord-309582-ihrj84hr	97	28	and	and	CC
cord-309582-ihrj84hr	97	29	therapies	therapy	NNS
cord-309582-ihrj84hr	97	30	of	of	IN
cord-309582-ihrj84hr	97	31	COVID-19	covid-19	CD
cord-309582-ihrj84hr	97	32	patients	patient	NNS
cord-309582-ihrj84hr	97	33	,	,	,
cord-309582-ihrj84hr	97	34	and	and	CC
cord-309582-ihrj84hr	97	35	subsequently	subsequently	RB
cord-309582-ihrj84hr	97	36	informing	inform	VBG
cord-309582-ihrj84hr	97	37	well	well	RB
cord-309582-ihrj84hr	97	38	designed	design	VBN
cord-309582-ihrj84hr	97	39	,	,	,
cord-309582-ihrj84hr	97	40	adequately	adequately	RB
cord-309582-ihrj84hr	97	41	powered	powered	JJ
cord-309582-ihrj84hr	97	42	,	,	,
cord-309582-ihrj84hr	97	43	and	and	CC
cord-309582-ihrj84hr	97	44	well	well	RB
cord-309582-ihrj84hr	97	45	-	-	HYPH
cord-309582-ihrj84hr	97	46	funded	fund	VBN
cord-309582-ihrj84hr	97	47	randomized	randomize	VBN
cord-309582-ihrj84hr	97	48	controlled	control	VBN
cord-309582-ihrj84hr	97	49	trials	trial	NNS
cord-309582-ihrj84hr	97	50	.	.	.
cord-309582-ihrj84hr	98	1	The	the	DT
cord-309582-ihrj84hr	98	2	latter	latter	JJ
cord-309582-ihrj84hr	98	3	should	should	MD
cord-309582-ihrj84hr	98	4	take	take	VB
cord-309582-ihrj84hr	98	5	priority	priority	NN
cord-309582-ihrj84hr	98	6	,	,	,
cord-309582-ihrj84hr	98	7	at	at	IN
cord-309582-ihrj84hr	98	8	least	least	RBS
cord-309582-ihrj84hr	98	9	temporarily	temporarily	RB
cord-309582-ihrj84hr	98	10	,	,	,
cord-309582-ihrj84hr	98	11	over	over	IN
cord-309582-ihrj84hr	98	12	other	other	JJ
cord-309582-ihrj84hr	98	13	competing	compete	VBG
cord-309582-ihrj84hr	98	14	clinical	clinical	JJ
cord-309582-ihrj84hr	98	15	trials	trial	NNS
cord-309582-ihrj84hr	98	16	.	.	.
cord-309582-ihrj84hr	99	1	Moreover	moreover	RB
cord-309582-ihrj84hr	99	2	,	,	,
cord-309582-ihrj84hr	99	3	patients	patient	NNS
cord-309582-ihrj84hr	99	4	and	and	CC
cord-309582-ihrj84hr	99	5	clinicians	clinician	NNS
cord-309582-ihrj84hr	99	6	should	should	MD
cord-309582-ihrj84hr	99	7	be	be	VB
cord-309582-ihrj84hr	99	8	encouraged	encourage	VBN
cord-309582-ihrj84hr	99	9	to	to	TO
cord-309582-ihrj84hr	99	10	participate	participate	VB
cord-309582-ihrj84hr	99	11	in	in	IN
cord-309582-ihrj84hr	99	12	such	such	JJ
cord-309582-ihrj84hr	99	13	initiatives	initiative	NNS
cord-309582-ihrj84hr	99	14	[	[	-LRB-
cord-309582-ihrj84hr	99	15	23	23	CD
cord-309582-ihrj84hr	99	16	]	]	-RRB-
cord-309582-ihrj84hr	99	17	.	.	.
cord-309582-ihrj84hr	100	1	Time	time	NN
cord-309582-ihrj84hr	100	2	limitation	limitation	NN
cord-309582-ihrj84hr	100	3	is	be	VBZ
cord-309582-ihrj84hr	100	4	a	a	DT
cord-309582-ihrj84hr	100	5	major	major	JJ
cord-309582-ihrj84hr	100	6	factor	factor	NN
cord-309582-ihrj84hr	100	7	leading	lead	VBG
cord-309582-ihrj84hr	100	8	to	to	IN
cord-309582-ihrj84hr	100	9	the	the	DT
cord-309582-ihrj84hr	100	10	incompleteness	incompleteness	NN
cord-309582-ihrj84hr	100	11	of	of	IN
cord-309582-ihrj84hr	100	12	clinical	clinical	JJ
cord-309582-ihrj84hr	100	13	trials	trial	NNS
cord-309582-ihrj84hr	100	14	during	during	IN
cord-309582-ihrj84hr	100	15	infectious	infectious	JJ
cord-309582-ihrj84hr	100	16	diseases	disease	NNS
cord-309582-ihrj84hr	100	17	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	100	18	.	.	.
cord-309582-ihrj84hr	101	1	During	during	IN
cord-309582-ihrj84hr	101	2	the	the	DT
cord-309582-ihrj84hr	101	3	EV	EV	NNP
cord-309582-ihrj84hr	101	4	outbreak	outbreak	NN
cord-309582-ihrj84hr	101	5	in	in	IN
cord-309582-ihrj84hr	101	6	2014	2014	CD
cord-309582-ihrj84hr	101	7	,	,	,
cord-309582-ihrj84hr	101	8	the	the	DT
cord-309582-ihrj84hr	101	9	National	National	NNP
cord-309582-ihrj84hr	101	10	Institutes	Institutes	NNPS
cord-309582-ihrj84hr	101	11	of	of	IN
cord-309582-ihrj84hr	101	12	Health	Health	NNP
cord-309582-ihrj84hr	101	13	took	take	VBD
cord-309582-ihrj84hr	101	14	several	several	JJ
cord-309582-ihrj84hr	101	15	months	month	NNS
cord-309582-ihrj84hr	101	16	to	to	TO
cord-309582-ihrj84hr	101	17	plan	plan	VB
cord-309582-ihrj84hr	101	18	and	and	CC
cord-309582-ihrj84hr	101	19	launch	launch	VB
cord-309582-ihrj84hr	101	20	the	the	DT
cord-309582-ihrj84hr	101	21	PREVAIL	prevail	JJ
cord-309582-ihrj84hr	101	22	II	II	NNP
cord-309582-ihrj84hr	101	23	trial	trial	NN
cord-309582-ihrj84hr	101	24	.	.	.
cord-309582-ihrj84hr	102	1	Unfortunately	unfortunately	RB
cord-309582-ihrj84hr	102	2	,	,	,
cord-309582-ihrj84hr	102	3	this	this	DT
cord-309582-ihrj84hr	102	4	trial	trial	NN
cord-309582-ihrj84hr	102	5	was	be	VBD
cord-309582-ihrj84hr	102	6	never	never	RB
cord-309582-ihrj84hr	102	7	completed	complete	VBN
cord-309582-ihrj84hr	102	8	while	while	IN
cord-309582-ihrj84hr	102	9	drawing	draw	VBG
cord-309582-ihrj84hr	102	10	on	on	RP
cord-309582-ihrj84hr	102	11	very	very	RB
cord-309582-ihrj84hr	102	12	significant	significant	JJ
cord-309582-ihrj84hr	102	13	resources	resource	NNS
cord-309582-ihrj84hr	102	14	[	[	-LRB-
cord-309582-ihrj84hr	102	15	18	18	CD
cord-309582-ihrj84hr	102	16	]	]	-RRB-
cord-309582-ihrj84hr	102	17	.	.	.
cord-309582-ihrj84hr	103	1	To	to	TO
cord-309582-ihrj84hr	103	2	overcome	overcome	VB
cord-309582-ihrj84hr	103	3	issues	issue	NNS
cord-309582-ihrj84hr	103	4	related	relate	VBN
cord-309582-ihrj84hr	103	5	to	to	IN
cord-309582-ihrj84hr	103	6	research	research	NN
cord-309582-ihrj84hr	103	7	during	during	IN
cord-309582-ihrj84hr	103	8	pandemic	pandemic	JJ
cord-309582-ihrj84hr	103	9	crises	crisis	NNS
cord-309582-ihrj84hr	103	10	and	and	CC
cord-309582-ihrj84hr	103	11	to	to	TO
cord-309582-ihrj84hr	103	12	avoid	avoid	VB
cord-309582-ihrj84hr	103	13	publication	publication	NN
cord-309582-ihrj84hr	103	14	bias	bias	NN
cord-309582-ihrj84hr	103	15	a	a	DT
cord-309582-ihrj84hr	103	16	group	group	NN
cord-309582-ihrj84hr	103	17	of	of	IN
cord-309582-ihrj84hr	103	18	public	public	JJ
cord-309582-ihrj84hr	103	19	health	health	NN
cord-309582-ihrj84hr	103	20	experts	expert	NNS
cord-309582-ihrj84hr	103	21	have	have	VBP
cord-309582-ihrj84hr	103	22	advocated	advocate	VBN
cord-309582-ihrj84hr	103	23	the	the	DT
cord-309582-ihrj84hr	103	24	use	use	NN
cord-309582-ihrj84hr	103	25	of	of	IN
cord-309582-ihrj84hr	103	26	a	a	DT
cord-309582-ihrj84hr	103	27	model	model	NN
cord-309582-ihrj84hr	103	28	called	call	VBN
cord-309582-ihrj84hr	103	29	"	"	``
cord-309582-ihrj84hr	103	30	core	core	NN
cord-309582-ihrj84hr	103	31	protocol	protocol	NN
cord-309582-ihrj84hr	103	32	"	"	''
cord-309582-ihrj84hr	103	33	[	[	-LRB-
cord-309582-ihrj84hr	103	34	24	24	CD
cord-309582-ihrj84hr	103	35	]	]	-RRB-
cord-309582-ihrj84hr	103	36	.	.	.
cord-309582-ihrj84hr	104	1	This	this	DT
cord-309582-ihrj84hr	104	2	model	model	NN
cord-309582-ihrj84hr	104	3	describes	describe	VBZ
cord-309582-ihrj84hr	104	4	the	the	DT
cord-309582-ihrj84hr	104	5	implementation	implementation	NN
cord-309582-ihrj84hr	104	6	of	of	IN
cord-309582-ihrj84hr	104	7	multiple	multiple	JJ
cord-309582-ihrj84hr	104	8	interventions	intervention	NNS
cord-309582-ihrj84hr	104	9	addressing	address	VBG
cord-309582-ihrj84hr	104	10	a	a	DT
cord-309582-ihrj84hr	104	11	single	single	JJ
cord-309582-ihrj84hr	104	12	disease	disease	NN
cord-309582-ihrj84hr	104	13	at	at	IN
cord-309582-ihrj84hr	104	14	the	the	DT
cord-309582-ihrj84hr	104	15	same	same	JJ
cord-309582-ihrj84hr	104	16	time	time	NN
cord-309582-ihrj84hr	104	17	such	such	JJ
cord-309582-ihrj84hr	104	18	as	as	IN
cord-309582-ihrj84hr	104	19	using	use	VBG
cord-309582-ihrj84hr	104	20	different	different	JJ
cord-309582-ihrj84hr	104	21	off	off	IN
cord-309582-ihrj84hr	104	22	label	label	NN
cord-309582-ihrj84hr	104	23	medications	medication	NNS
cord-309582-ihrj84hr	104	24	to	to	TO
cord-309582-ihrj84hr	104	25	treat	treat	VB
cord-309582-ihrj84hr	104	26	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	104	27	,	,	,
cord-309582-ihrj84hr	104	28	or	or	CC
cord-309582-ihrj84hr	104	29	of	of	IN
cord-309582-ihrj84hr	104	30	a	a	DT
cord-309582-ihrj84hr	104	31	single	single	JJ
cord-309582-ihrj84hr	104	32	intervention	intervention	NN
cord-309582-ihrj84hr	104	33	targeting	target	VBG
cord-309582-ihrj84hr	104	34	multiple	multiple	JJ
cord-309582-ihrj84hr	104	35	diseases	disease	NNS
cord-309582-ihrj84hr	104	36	across	across	IN
cord-309582-ihrj84hr	104	37	different	different	JJ
cord-309582-ihrj84hr	104	38	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	104	39	such	such	JJ
cord-309582-ihrj84hr	104	40	as	as	IN
cord-309582-ihrj84hr	104	41	Remdesivir	Remdesivir	NNP
cord-309582-ihrj84hr	104	42	which	which	WDT
cord-309582-ihrj84hr	104	43	was	be	VBD
cord-309582-ihrj84hr	104	44	used	use	VBN
cord-309582-ihrj84hr	104	45	to	to	TO
cord-309582-ihrj84hr	104	46	treat	treat	VB
cord-309582-ihrj84hr	104	47	EV	EV	NNP
cord-309582-ihrj84hr	104	48	and	and	CC
cord-309582-ihrj84hr	104	49	now	now	RB
cord-309582-ihrj84hr	104	50	is	be	VBZ
cord-309582-ihrj84hr	104	51	being	be	VBG
cord-309582-ihrj84hr	104	52	studies	study	NNS
cord-309582-ihrj84hr	104	53	in	in	IN
cord-309582-ihrj84hr	104	54	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	104	55	.	.	.
cord-309582-ihrj84hr	105	1	This	this	DT
cord-309582-ihrj84hr	105	2	approach	approach	NN
cord-309582-ihrj84hr	105	3	aims	aim	VBZ
cord-309582-ihrj84hr	105	4	to	to	TO
cord-309582-ihrj84hr	105	5	minimize	minimize	VB
cord-309582-ihrj84hr	105	6	the	the	DT
cord-309582-ihrj84hr	105	7	time	time	NN
cord-309582-ihrj84hr	105	8	required	require	VBN
cord-309582-ihrj84hr	105	9	to	to	TO
cord-309582-ihrj84hr	105	10	complete	complete	VB
cord-309582-ihrj84hr	105	11	high	high	JJ
cord-309582-ihrj84hr	105	12	quality	quality	NN
cord-309582-ihrj84hr	105	13	clinical	clinical	JJ
cord-309582-ihrj84hr	105	14	trials	trial	NNS
cord-309582-ihrj84hr	105	15	during	during	IN
cord-309582-ihrj84hr	105	16	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	105	17	,	,	,
cord-309582-ihrj84hr	105	18	with	with	IN
cord-309582-ihrj84hr	105	19	recognition	recognition	NN
cord-309582-ihrj84hr	105	20	of	of	IN
cord-309582-ihrj84hr	105	21	the	the	DT
cord-309582-ihrj84hr	105	22	additional	additional	JJ
cord-309582-ihrj84hr	105	23	important	important	JJ
cord-309582-ihrj84hr	105	24	role	role	NN
cord-309582-ihrj84hr	105	25	of	of	IN
cord-309582-ihrj84hr	105	26	timely	timely	JJ
cord-309582-ihrj84hr	105	27	interim	interim	JJ
cord-309582-ihrj84hr	105	28	analyses	analysis	NNS
cord-309582-ihrj84hr	105	29	to	to	TO
cord-309582-ihrj84hr	105	30	limit	limit	VB
cord-309582-ihrj84hr	105	31	futility	futility	NN
cord-309582-ihrj84hr	105	32	or	or	CC
cord-309582-ihrj84hr	105	33	harm	harm	NN
cord-309582-ihrj84hr	105	34	and	and	CC
cord-309582-ihrj84hr	105	35	enhance	enhance	VB
cord-309582-ihrj84hr	105	36	the	the	DT
cord-309582-ihrj84hr	105	37	early	early	JJ
cord-309582-ihrj84hr	105	38	recognition	recognition	NN
cord-309582-ihrj84hr	105	39	of	of	IN
cord-309582-ihrj84hr	105	40	efficacy	efficacy	NN
cord-309582-ihrj84hr	105	41	.	.	.
cord-309582-ihrj84hr	106	1	Subsequent	subsequent	JJ
cord-309582-ihrj84hr	106	2	publication	publication	NN
cord-309582-ihrj84hr	106	3	of	of	IN
cord-309582-ihrj84hr	106	4	results	result	NNS
cord-309582-ihrj84hr	106	5	would	would	MD
cord-309582-ihrj84hr	106	6	only	only	RB
cord-309582-ihrj84hr	106	7	be	be	VB
cord-309582-ihrj84hr	106	8	carried	carry	VBN
cord-309582-ihrj84hr	106	9	out	out	RP
cord-309582-ihrj84hr	106	10	if	if	IN
cord-309582-ihrj84hr	106	11	pre	pre	JJ
cord-309582-ihrj84hr	106	12	-	-	JJ
cord-309582-ihrj84hr	106	13	set	set	JJ
cord-309582-ihrj84hr	106	14	criteria	criterion	NNS
cord-309582-ihrj84hr	106	15	of	of	IN
cord-309582-ihrj84hr	106	16	efficacy	efficacy	NN
cord-309582-ihrj84hr	106	17	or	or	CC
cord-309582-ihrj84hr	106	18	effectiveness	effectiveness	NN
cord-309582-ihrj84hr	106	19	are	be	VBP
cord-309582-ihrj84hr	106	20	met	meet	VBN
cord-309582-ihrj84hr	106	21	(	(	-LRB-
cord-309582-ihrj84hr	106	22	which	which	WDT
cord-309582-ihrj84hr	106	23	may	may	MD
cord-309582-ihrj84hr	106	24	not	not	RB
cord-309582-ihrj84hr	106	25	be	be	VB
cord-309582-ihrj84hr	106	26	the	the	DT
cord-309582-ihrj84hr	106	27	case	case	NN
cord-309582-ihrj84hr	106	28	until	until	IN
cord-309582-ihrj84hr	106	29	further	further	JJ
cord-309582-ihrj84hr	106	30	enrolment	enrolment	NN
cord-309582-ihrj84hr	106	31	is	be	VBZ
cord-309582-ihrj84hr	106	32	reached	reach	VBN
cord-309582-ihrj84hr	106	33	during	during	IN
cord-309582-ihrj84hr	106	34	subsequent	subsequent	JJ
cord-309582-ihrj84hr	106	35	pandemics	pandemic	NNS
cord-309582-ihrj84hr	106	36	)	)	-RRB-
cord-309582-ihrj84hr	106	37	.	.	.
cord-309582-ihrj84hr	107	1	The	the	DT
cord-309582-ihrj84hr	107	2	rapid	rapid	JJ
cord-309582-ihrj84hr	107	3	and	and	CC
cord-309582-ihrj84hr	107	4	unpredictable	unpredictable	JJ
cord-309582-ihrj84hr	107	5	nature	nature	NN
cord-309582-ihrj84hr	107	6	of	of	IN
cord-309582-ihrj84hr	107	7	many	many	JJ
cord-309582-ihrj84hr	107	8	pandemic	pandemic	NN
cord-309582-ihrj84hr	107	9	infectious	infectious	JJ
cord-309582-ihrj84hr	107	10	diseases	disease	NNS
cord-309582-ihrj84hr	107	11	such	such	JJ
cord-309582-ihrj84hr	107	12	as	as	IN
cord-309582-ihrj84hr	107	13	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	107	14	makes	make	VBZ
cord-309582-ihrj84hr	107	15	it	-PRON-	PRP
cord-309582-ihrj84hr	107	16	impossible	impossible	JJ
cord-309582-ihrj84hr	107	17	for	for	IN
cord-309582-ihrj84hr	107	18	a	a	DT
cord-309582-ihrj84hr	107	19	limited	limited	JJ
cord-309582-ihrj84hr	107	20	number	number	NN
cord-309582-ihrj84hr	107	21	of	of	IN
cord-309582-ihrj84hr	107	22	researchers	researcher	NNS
cord-309582-ihrj84hr	107	23	to	to	TO
cord-309582-ihrj84hr	107	24	produce	produce	VB
cord-309582-ihrj84hr	107	25	meaningful	meaningful	JJ
cord-309582-ihrj84hr	107	26	clinical	clinical	JJ
cord-309582-ihrj84hr	107	27	results	result	NNS
cord-309582-ihrj84hr	107	28	.	.	.
cord-309582-ihrj84hr	108	1	To	to	TO
cord-309582-ihrj84hr	108	2	overcome	overcome	VB
cord-309582-ihrj84hr	108	3	such	such	PDT
cord-309582-ihrj84hr	108	4	an	an	DT
cord-309582-ihrj84hr	108	5	obstacle	obstacle	NN
cord-309582-ihrj84hr	108	6	,	,	,
cord-309582-ihrj84hr	108	7	multi	multi	JJ
cord-309582-ihrj84hr	108	8	-	-	JJ
cord-309582-ihrj84hr	108	9	center	center	JJ
cord-309582-ihrj84hr	108	10	trials	trial	NNS
cord-309582-ihrj84hr	108	11	involving	involve	VBG
cord-309582-ihrj84hr	108	12	different	different	JJ
cord-309582-ihrj84hr	108	13	countries	country	NNS
cord-309582-ihrj84hr	108	14	with	with	IN
cord-309582-ihrj84hr	108	15	two	two	CD
cord-309582-ihrj84hr	108	16	-	-	HYPH
cord-309582-ihrj84hr	108	17	way	way	NN
cord-309582-ihrj84hr	108	18	exchange	exchange	NN
cord-309582-ihrj84hr	108	19	of	of	IN
cord-309582-ihrj84hr	108	20	information	information	NN
cord-309582-ihrj84hr	108	21	,	,	,
cord-309582-ihrj84hr	108	22	protocols	protocol	NNS
cord-309582-ihrj84hr	108	23	and	and	CC
cord-309582-ihrj84hr	108	24	procedures	procedure	NNS
cord-309582-ihrj84hr	108	25	is	be	VBZ
cord-309582-ihrj84hr	108	26	an	an	DT
cord-309582-ihrj84hr	108	27	essential	essential	JJ
cord-309582-ihrj84hr	108	28	part	part	NN
cord-309582-ihrj84hr	108	29	of	of	IN
cord-309582-ihrj84hr	108	30	the	the	DT
cord-309582-ihrj84hr	108	31	global	global	JJ
cord-309582-ihrj84hr	108	32	approach	approach	NN
cord-309582-ihrj84hr	108	33	to	to	IN
cord-309582-ihrj84hr	108	34	any	any	DT
cord-309582-ihrj84hr	108	35	pandemic	pandemic	NN
cord-309582-ihrj84hr	108	36	situation	situation	NN
cord-309582-ihrj84hr	108	37	[	[	-LRB-
cord-309582-ihrj84hr	108	38	25	25	CD
cord-309582-ihrj84hr	108	39	]	]	-RRB-
cord-309582-ihrj84hr	108	40	.	.	.
cord-309582-ihrj84hr	109	1	Such	such	JJ
cord-309582-ihrj84hr	109	2	collaboration	collaboration	NN
cord-309582-ihrj84hr	109	3	should	should	MD
cord-309582-ihrj84hr	109	4	be	be	VB
cord-309582-ihrj84hr	109	5	supported	support	VBN
cord-309582-ihrj84hr	109	6	and	and	CC
cord-309582-ihrj84hr	109	7	facilitated	facilitate	VBN
cord-309582-ihrj84hr	109	8	by	by	IN
cord-309582-ihrj84hr	109	9	regulators	regulator	NNS
cord-309582-ihrj84hr	109	10	in	in	IN
cord-309582-ihrj84hr	109	11	order	order	NN
cord-309582-ihrj84hr	109	12	to	to	TO
cord-309582-ihrj84hr	109	13	preserve	preserve	VB
cord-309582-ihrj84hr	109	14	resources	resource	NNS
cord-309582-ihrj84hr	109	15	and	and	CC
cord-309582-ihrj84hr	109	16	avoid	avoid	VB
cord-309582-ihrj84hr	109	17	underpowered	underpowered	JJ
cord-309582-ihrj84hr	109	18	studies	study	NNS
cord-309582-ihrj84hr	109	19	,	,	,
cord-309582-ihrj84hr	109	20	while	while	IN
cord-309582-ihrj84hr	109	21	achieving	achieve	VBG
cord-309582-ihrj84hr	109	22	the	the	DT
cord-309582-ihrj84hr	109	23	planned	plan	VBN
cord-309582-ihrj84hr	109	24	outcomes	outcome	NNS
cord-309582-ihrj84hr	109	25	.	.	.
cord-309582-ihrj84hr	110	1	This	this	DT
cord-309582-ihrj84hr	110	2	will	will	MD
cord-309582-ihrj84hr	110	3	also	also	RB
cord-309582-ihrj84hr	110	4	help	help	VB
cord-309582-ihrj84hr	110	5	countries	country	NNS
cord-309582-ihrj84hr	110	6	with	with	IN
cord-309582-ihrj84hr	110	7	limited	limited	JJ
cord-309582-ihrj84hr	110	8	resources	resource	NNS
cord-309582-ihrj84hr	110	9	that	that	WDT
cord-309582-ihrj84hr	110	10	report	report	VBP
cord-309582-ihrj84hr	110	11	on	on	IN
cord-309582-ihrj84hr	110	12	lower	low	JJR
cord-309582-ihrj84hr	110	13	numbers	number	NNS
cord-309582-ihrj84hr	110	14	of	of	IN
cord-309582-ihrj84hr	110	15	cases	case	NNS
cord-309582-ihrj84hr	110	16	due	due	JJ
cord-309582-ihrj84hr	110	17	to	to	IN
cord-309582-ihrj84hr	110	18	unavailability	unavailability	NN
cord-309582-ihrj84hr	110	19	of	of	IN
cord-309582-ihrj84hr	110	20	testing	testing	NN
cord-309582-ihrj84hr	110	21	.	.	.
cord-309582-ihrj84hr	111	1	An	an	DT
cord-309582-ihrj84hr	111	2	excellent	excellent	JJ
cord-309582-ihrj84hr	111	3	example	example	NN
cord-309582-ihrj84hr	111	4	of	of	IN
cord-309582-ihrj84hr	111	5	this	this	DT
cord-309582-ihrj84hr	111	6	kind	kind	NN
cord-309582-ihrj84hr	111	7	of	of	IN
cord-309582-ihrj84hr	111	8	collaboration	collaboration	NN
cord-309582-ihrj84hr	111	9	is	be	VBZ
cord-309582-ihrj84hr	111	10	the	the	DT
cord-309582-ihrj84hr	111	11	SOLIDARITY	SOLIDARITY	NNP
cord-309582-ihrj84hr	111	12	trial	trial	NN
cord-309582-ihrj84hr	111	13	-	-	:
cord-309582-ihrj84hr	111	14	a	a	DT
cord-309582-ihrj84hr	111	15	World	World	NNP
cord-309582-ihrj84hr	111	16	Health	Health	NNP
cord-309582-ihrj84hr	111	17	Organization	Organization	NNP
cord-309582-ihrj84hr	111	18	-	-	HYPH
cord-309582-ihrj84hr	111	19	funded	fund	VBN
cord-309582-ihrj84hr	111	20	international	international	JJ
cord-309582-ihrj84hr	111	21	study	study	NN
cord-309582-ihrj84hr	111	22	of	of	IN
cord-309582-ihrj84hr	111	23	potential	potential	JJ
cord-309582-ihrj84hr	111	24	treatments	treatment	NNS
cord-309582-ihrj84hr	111	25	for	for	IN
cord-309582-ihrj84hr	111	26	COVID-19	covid-19	NN
cord-309582-ihrj84hr	111	27	to	to	TO
cord-309582-ihrj84hr	111	28	be	be	VB
cord-309582-ihrj84hr	111	29	conducted	conduct	VBN
cord-309582-ihrj84hr	111	30	in	in	IN
cord-309582-ihrj84hr	111	31	Asia	Asia	NNP
cord-309582-ihrj84hr	111	32	,	,	,
cord-309582-ihrj84hr	111	33	South	South	NNP
cord-309582-ihrj84hr	111	34	Africa	Africa	NNP
cord-309582-ihrj84hr	111	35	,	,	,
cord-309582-ihrj84hr	111	36	Europe	Europe	NNP
cord-309582-ihrj84hr	111	37	,	,	,
cord-309582-ihrj84hr	111	38	and	and	CC
cord-309582-ihrj84hr	111	39	the	the	DT
cord-309582-ihrj84hr	111	40	Americas	Americas	NNPS
cord-309582-ihrj84hr	111	41	[	[	-LRB-
cord-309582-ihrj84hr	111	42	26	26	CD
cord-309582-ihrj84hr	111	43	]	]	-RRB-
cord-309582-ihrj84hr	111	44	.	.	.
cord-309582-ihrj84hr	112	1	In	in	IN
cord-309582-ihrj84hr	112	2	pandemic	pandemic	JJ
cord-309582-ihrj84hr	112	3	times	time	NNS
cord-309582-ihrj84hr	112	4	,	,	,
cord-309582-ihrj84hr	112	5	therapeutic	therapeutic	JJ
cord-309582-ihrj84hr	112	6	priority	priority	NN
cord-309582-ihrj84hr	112	7	must	must	MD
cord-309582-ihrj84hr	112	8	be	be	VB
cord-309582-ihrj84hr	112	9	given	give	VBN
cord-309582-ihrj84hr	112	10	to	to	TO
cord-309582-ihrj84hr	112	11	research	research	VB
cord-309582-ihrj84hr	112	12	focusing	focus	VBG
cord-309582-ihrj84hr	112	13	on	on	IN
cord-309582-ihrj84hr	112	14	interventions	intervention	NNS
cord-309582-ihrj84hr	112	15	.	.	.
cord-309582-ihrj84hr	113	1	Investigators	investigator	NNS
cord-309582-ihrj84hr	113	2	must	must	MD
cord-309582-ihrj84hr	113	3	concentrate	concentrate	VB
cord-309582-ihrj84hr	113	4	on	on	IN
cord-309582-ihrj84hr	113	5	studying	study	VBG
cord-309582-ihrj84hr	113	6	the	the	DT
cord-309582-ihrj84hr	113	7	effectiveness	effectiveness	NN
cord-309582-ihrj84hr	113	8	of	of	IN
cord-309582-ihrj84hr	113	9	already	already	RB
cord-309582-ihrj84hr	113	10	developed	develop	VBN
cord-309582-ihrj84hr	113	11	and	and	CC
cord-309582-ihrj84hr	113	12	approved	approve	VBN
cord-309582-ihrj84hr	113	13	medications	medication	NNS
cord-309582-ihrj84hr	113	14	used	use	VBN
cord-309582-ihrj84hr	113	15	for	for	IN
cord-309582-ihrj84hr	113	16	similar	similar	JJ
cord-309582-ihrj84hr	113	17	viruses	virus	NNS
cord-309582-ihrj84hr	113	18	.	.	.
cord-309582-ihrj84hr	114	1	The	the	DT
cord-309582-ihrj84hr	114	2	development	development	NN
cord-309582-ihrj84hr	114	3	of	of	IN
cord-309582-ihrj84hr	114	4	new	new	JJ
cord-309582-ihrj84hr	114	5	drugs	drug	NNS
cord-309582-ihrj84hr	114	6	and	and	CC
cord-309582-ihrj84hr	114	7	testing	test	VBG
cord-309582-ihrj84hr	114	8	through	through	IN
cord-309582-ihrj84hr	114	9	multi	multi	JJ
cord-309582-ihrj84hr	114	10	-	-	NNS
cord-309582-ihrj84hr	114	11	phases	phase	NNS
cord-309582-ihrj84hr	114	12	during	during	IN
cord-309582-ihrj84hr	114	13	such	such	JJ
cord-309582-ihrj84hr	114	14	emergencies	emergency	NNS
cord-309582-ihrj84hr	114	15	may	may	MD
cord-309582-ihrj84hr	114	16	only	only	RB
cord-309582-ihrj84hr	114	17	be	be	VB
cord-309582-ihrj84hr	114	18	of	of	IN
cord-309582-ihrj84hr	114	19	limited	limited	JJ
cord-309582-ihrj84hr	114	20	benefit	benefit	NN
cord-309582-ihrj84hr	114	21	for	for	IN
cord-309582-ihrj84hr	114	22	the	the	DT
cord-309582-ihrj84hr	114	23	current	current	JJ
cord-309582-ihrj84hr	114	24	pandemic	pandemic	NN
cord-309582-ihrj84hr	114	25	affected	affect	VBN
cord-309582-ihrj84hr	114	26	patients	patient	NNS
cord-309582-ihrj84hr	114	27	,	,	,
cord-309582-ihrj84hr	114	28	however	however	RB
cord-309582-ihrj84hr	114	29	results	result	NNS
cord-309582-ihrj84hr	114	30	will	will	MD
cord-309582-ihrj84hr	114	31	of	of	IN
cord-309582-ihrj84hr	114	32	course	course	NN
cord-309582-ihrj84hr	114	33	be	be	VB
cord-309582-ihrj84hr	114	34	of	of	IN
cord-309582-ihrj84hr	114	35	help	help	NN
cord-309582-ihrj84hr	114	36	for	for	IN
cord-309582-ihrj84hr	114	37	similar	similar	JJ
cord-309582-ihrj84hr	114	38	future	future	JJ
cord-309582-ihrj84hr	114	39	pandemics	pandemic	NNS
cord-309582-ihrj84hr	114	40	.	.	.
cord-309582-ihrj84hr	115	1	August	August	NNP
cord-309582-ihrj84hr	115	2	6	6	CD
cord-309582-ihrj84hr	115	3	,	,	,
cord-309582-ihrj84hr	115	4	2020	2020	CD
cord-309582-ihrj84hr	116	1	Volume	volume	NN
cord-309582-ihrj84hr	116	2	8	8	CD
cord-309582-ihrj84hr	116	3	Issue	issue	NN
cord-309582-ihrj84hr	116	4	15	15	CD
cord-309582-ihrj84hr	117	1	As	as	IN
cord-309582-ihrj84hr	117	2	discussed	discuss	VBN
cord-309582-ihrj84hr	117	3	above	above	RB
cord-309582-ihrj84hr	117	4	,	,	,
cord-309582-ihrj84hr	117	5	modifications	modification	NNS
cord-309582-ihrj84hr	117	6	of	of	IN
cord-309582-ihrj84hr	117	7	policies	policy	NNS
cord-309582-ihrj84hr	117	8	and	and	CC
cord-309582-ihrj84hr	117	9	regulations	regulation	NNS
cord-309582-ihrj84hr	117	10	established	establish	VBN
cord-309582-ihrj84hr	117	11	by	by	IN
cord-309582-ihrj84hr	117	12	local	local	JJ
cord-309582-ihrj84hr	117	13	IRBs	irb	NNS
cord-309582-ihrj84hr	117	14	during	during	IN
cord-309582-ihrj84hr	117	15	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	117	16	to	to	TO
cord-309582-ihrj84hr	117	17	maintain	maintain	VB
cord-309582-ihrj84hr	117	18	ongoing	ongoing	JJ
cord-309582-ihrj84hr	117	19	studies	study	NNS
cord-309582-ihrj84hr	117	20	should	should	MD
cord-309582-ihrj84hr	117	21	also	also	RB
cord-309582-ihrj84hr	117	22	be	be	VB
cord-309582-ihrj84hr	117	23	applied	apply	VBN
cord-309582-ihrj84hr	117	24	to	to	IN
cord-309582-ihrj84hr	117	25	new	new	JJ
cord-309582-ihrj84hr	117	26	clinical	clinical	JJ
cord-309582-ihrj84hr	117	27	trial	trial	NN
cord-309582-ihrj84hr	117	28	submissions	submission	NNS
cord-309582-ihrj84hr	117	29	involving	involve	VBG
cord-309582-ihrj84hr	117	30	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	117	31	patients	patient	NNS
cord-309582-ihrj84hr	117	32	.	.	.
cord-309582-ihrj84hr	118	1	It	-PRON-	PRP
cord-309582-ihrj84hr	118	2	is	be	VBZ
cord-309582-ihrj84hr	118	3	essential	essential	JJ
cord-309582-ihrj84hr	118	4	to	to	TO
cord-309582-ihrj84hr	118	5	discover	discover	VB
cord-309582-ihrj84hr	118	6	new	new	JJ
cord-309582-ihrj84hr	118	7	drugs	drug	NNS
cord-309582-ihrj84hr	118	8	to	to	TO
cord-309582-ihrj84hr	118	9	effectively	effectively	RB
cord-309582-ihrj84hr	118	10	fight	fight	VB
cord-309582-ihrj84hr	118	11	what	what	WP
cord-309582-ihrj84hr	118	12	are	be	VBP
cord-309582-ihrj84hr	118	13	likely	likely	RB
cord-309582-ihrj84hr	118	14	repeated	repeat	VBN
cord-309582-ihrj84hr	118	15	infectious	infectious	JJ
cord-309582-ihrj84hr	118	16	diseases	disease	NNS
cord-309582-ihrj84hr	118	17	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	118	18	in	in	IN
cord-309582-ihrj84hr	118	19	time	time	NN
cord-309582-ihrj84hr	118	20	.	.	.
cord-309582-ihrj84hr	119	1	Off	off	IN
cord-309582-ihrj84hr	119	2	-	-	HYPH
cord-309582-ihrj84hr	119	3	label	label	NN
cord-309582-ihrj84hr	119	4	use	use	NN
cord-309582-ihrj84hr	119	5	of	of	IN
cord-309582-ihrj84hr	119	6	available	available	JJ
cord-309582-ihrj84hr	119	7	medications	medication	NNS
cord-309582-ihrj84hr	119	8	has	have	VBZ
cord-309582-ihrj84hr	119	9	disadvantages	disadvantage	NNS
cord-309582-ihrj84hr	119	10	such	such	JJ
cord-309582-ihrj84hr	119	11	as	as	IN
cord-309582-ihrj84hr	119	12	unknown	unknown	JJ
cord-309582-ihrj84hr	119	13	efficacy	efficacy	NN
cord-309582-ihrj84hr	119	14	,	,	,
cord-309582-ihrj84hr	119	15	side	side	NN
cord-309582-ihrj84hr	119	16	effects	effect	NNS
cord-309582-ihrj84hr	119	17	and	and	CC
cord-309582-ihrj84hr	119	18	drug	drug	NN
cord-309582-ihrj84hr	119	19	-	-	HYPH
cord-309582-ihrj84hr	119	20	drug	drug	NN
cord-309582-ihrj84hr	119	21	interactions	interaction	NNS
cord-309582-ihrj84hr	119	22	.	.	.
cord-309582-ihrj84hr	120	1	Therefore	therefore	RB
cord-309582-ihrj84hr	120	2	,	,	,
cord-309582-ihrj84hr	120	3	when	when	WRB
cord-309582-ihrj84hr	120	4	the	the	DT
cord-309582-ihrj84hr	120	5	pandemic	pandemic	NN
cord-309582-ihrj84hr	120	6	is	be	VBZ
cord-309582-ihrj84hr	120	7	over	over	RB
cord-309582-ihrj84hr	120	8	,	,	,
cord-309582-ihrj84hr	120	9	clinical	clinical	JJ
cord-309582-ihrj84hr	120	10	trials	trial	NNS
cord-309582-ihrj84hr	120	11	that	that	WDT
cord-309582-ihrj84hr	120	12	started	start	VBD
cord-309582-ihrj84hr	120	13	during	during	IN
cord-309582-ihrj84hr	120	14	the	the	DT
cord-309582-ihrj84hr	120	15	pandemic	pandemic	NN
cord-309582-ihrj84hr	120	16	of	of	IN
cord-309582-ihrj84hr	120	17	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	120	18	should	should	MD
cord-309582-ihrj84hr	120	19	continue	continue	VB
cord-309582-ihrj84hr	120	20	with	with	IN
cord-309582-ihrj84hr	120	21	their	-PRON-	PRP$
cord-309582-ihrj84hr	120	22	findings	finding	NNS
cord-309582-ihrj84hr	120	23	published	publish	VBN
cord-309582-ihrj84hr	120	24	once	once	IN
cord-309582-ihrj84hr	120	25	the	the	DT
cord-309582-ihrj84hr	120	26	planned	plan	VBN
cord-309582-ihrj84hr	120	27	accrual	accrual	NN
cord-309582-ihrj84hr	120	28	and/or	and/or	CC
cord-309582-ihrj84hr	120	29	efficacy	efficacy	NN
cord-309582-ihrj84hr	120	30	,	,	,
cord-309582-ihrj84hr	120	31	harm	harm	NN
cord-309582-ihrj84hr	120	32	,	,	,
cord-309582-ihrj84hr	120	33	or	or	CC
cord-309582-ihrj84hr	120	34	futility	futility	NN
cord-309582-ihrj84hr	120	35	endpoints	endpoint	NNS
cord-309582-ihrj84hr	120	36	have	have	VBP
cord-309582-ihrj84hr	120	37	been	be	VBN
cord-309582-ihrj84hr	120	38	reached	reach	VBN
cord-309582-ihrj84hr	120	39	.	.	.
cord-309582-ihrj84hr	121	1	Other	other	JJ
cord-309582-ihrj84hr	121	2	studies	study	NNS
cord-309582-ihrj84hr	121	3	that	that	WDT
cord-309582-ihrj84hr	121	4	may	may	MD
cord-309582-ihrj84hr	121	5	have	have	VB
cord-309582-ihrj84hr	121	6	used	use	VBN
cord-309582-ihrj84hr	121	7	the	the	DT
cord-309582-ihrj84hr	121	8	earlier	early	RBR
cord-309582-ihrj84hr	121	9	described	describe	VBN
cord-309582-ihrj84hr	121	10	core	core	NN
cord-309582-ihrj84hr	121	11	protocol	protocol	NN
cord-309582-ihrj84hr	121	12	model	model	NN
cord-309582-ihrj84hr	121	13	should	should	MD
cord-309582-ihrj84hr	121	14	extend	extend	VB
cord-309582-ihrj84hr	121	15	across	across	IN
cord-309582-ihrj84hr	121	16	future	future	JJ
cord-309582-ihrj84hr	121	17	multiple	multiple	JJ
cord-309582-ihrj84hr	121	18	infectious	infectious	JJ
cord-309582-ihrj84hr	121	19	disease	disease	NN
cord-309582-ihrj84hr	121	20	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	121	21	[	[	-LRB-
cord-309582-ihrj84hr	121	22	24	24	CD
cord-309582-ihrj84hr	121	23	]	]	-RRB-
cord-309582-ihrj84hr	121	24	.	.	.
cord-309582-ihrj84hr	122	1	Due	due	IN
cord-309582-ihrj84hr	122	2	to	to	IN
cord-309582-ihrj84hr	122	3	the	the	DT
cord-309582-ihrj84hr	122	4	limited	limited	JJ
cord-309582-ihrj84hr	122	5	time	time	NN
cord-309582-ihrj84hr	122	6	available	available	JJ
cord-309582-ihrj84hr	122	7	to	to	TO
cord-309582-ihrj84hr	122	8	enroll	enroll	VB
cord-309582-ihrj84hr	122	9	the	the	DT
cord-309582-ihrj84hr	122	10	large	large	JJ
cord-309582-ihrj84hr	122	11	sample	sample	NN
cord-309582-ihrj84hr	122	12	sizes	size	NNS
cord-309582-ihrj84hr	122	13	of	of	IN
cord-309582-ihrj84hr	122	14	patients	patient	NNS
cord-309582-ihrj84hr	122	15	required	require	VBN
cord-309582-ihrj84hr	122	16	for	for	IN
cord-309582-ihrj84hr	122	17	many	many	JJ
cord-309582-ihrj84hr	122	18	high	high	JJ
cord-309582-ihrj84hr	122	19	-	-	HYPH
cord-309582-ihrj84hr	122	20	quality	quality	NN
cord-309582-ihrj84hr	122	21	clinical	clinical	JJ
cord-309582-ihrj84hr	122	22	trials	trial	NNS
cord-309582-ihrj84hr	122	23	,	,	,
cord-309582-ihrj84hr	122	24	and	and	CC
cord-309582-ihrj84hr	122	25	the	the	DT
cord-309582-ihrj84hr	122	26	enormous	enormous	JJ
cord-309582-ihrj84hr	122	27	resources	resource	NNS
cord-309582-ihrj84hr	122	28	required	require	VBN
cord-309582-ihrj84hr	122	29	during	during	IN
cord-309582-ihrj84hr	122	30	emergency	emergency	NN
cord-309582-ihrj84hr	122	31	pandemic	pandemic	NN
cord-309582-ihrj84hr	122	32	diseases	disease	NNS
cord-309582-ihrj84hr	122	33	,	,	,
cord-309582-ihrj84hr	122	34	earlier	early	JJR
cord-309582-ihrj84hr	122	35	preparation	preparation	NN
cord-309582-ihrj84hr	122	36	for	for	IN
cord-309582-ihrj84hr	122	37	future	future	JJ
cord-309582-ihrj84hr	122	38	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	122	39	is	be	VBZ
cord-309582-ihrj84hr	122	40	becoming	become	VBG
cord-309582-ihrj84hr	122	41	crucial	crucial	JJ
cord-309582-ihrj84hr	122	42	for	for	IN
cord-309582-ihrj84hr	122	43	producing	produce	VBG
cord-309582-ihrj84hr	122	44	meaningful	meaningful	JJ
cord-309582-ihrj84hr	122	45	research	research	NN
cord-309582-ihrj84hr	122	46	findings	finding	NNS
cord-309582-ihrj84hr	122	47	.	.	.
cord-309582-ihrj84hr	123	1	Such	such	JJ
cord-309582-ihrj84hr	123	2	planning	planning	NN
cord-309582-ihrj84hr	123	3	should	should	MD
cord-309582-ihrj84hr	123	4	include	include	VB
cord-309582-ihrj84hr	123	5	multi	multi	JJ
cord-309582-ihrj84hr	123	6	-	-	JJ
cord-309582-ihrj84hr	123	7	center	center	JJ
cord-309582-ihrj84hr	123	8	participation	participation	NN
cord-309582-ihrj84hr	123	9	from	from	IN
cord-309582-ihrj84hr	123	10	different	different	JJ
cord-309582-ihrj84hr	123	11	countries	country	NNS
cord-309582-ihrj84hr	123	12	to	to	TO
cord-309582-ihrj84hr	123	13	ensure	ensure	VB
cord-309582-ihrj84hr	123	14	sufficient	sufficient	JJ
cord-309582-ihrj84hr	123	15	sample	sample	NN
cord-309582-ihrj84hr	123	16	size	size	NN
cord-309582-ihrj84hr	123	17	and	and	CC
cord-309582-ihrj84hr	123	18	representative	representative	JJ
cord-309582-ihrj84hr	123	19	diverse	diverse	JJ
cord-309582-ihrj84hr	123	20	patient	patient	JJ
cord-309582-ihrj84hr	123	21	demographics	demographic	NNS
cord-309582-ihrj84hr	123	22	favoring	favor	VBG
cord-309582-ihrj84hr	123	23	broad	broad	JJ
cord-309582-ihrj84hr	123	24	generalizability	generalizability	NN
cord-309582-ihrj84hr	123	25	of	of	IN
cord-309582-ihrj84hr	123	26	results	result	NNS
cord-309582-ihrj84hr	123	27	and	and	CC
cord-309582-ihrj84hr	123	28	meaningful	meaningful	JJ
cord-309582-ihrj84hr	123	29	,	,	,
cord-309582-ihrj84hr	123	30	adequately	adequately	RB
cord-309582-ihrj84hr	123	31	powered	power	VBD
cord-309582-ihrj84hr	123	32	subgroup	subgroup	NN
cord-309582-ihrj84hr	123	33	analyses	analysis	NNS
cord-309582-ihrj84hr	123	34	[	[	-LRB-
cord-309582-ihrj84hr	123	35	27	27	CD
cord-309582-ihrj84hr	123	36	]	]	-RRB-
cord-309582-ihrj84hr	123	37	.	.	.
cord-309582-ihrj84hr	124	1	Such	such	JJ
cord-309582-ihrj84hr	124	2	participation	participation	NN
cord-309582-ihrj84hr	124	3	requires	require	VBZ
cord-309582-ihrj84hr	124	4	research	research	NN
cord-309582-ihrj84hr	124	5	capacity	capacity	NN
cord-309582-ihrj84hr	124	6	building	building	NN
cord-309582-ihrj84hr	124	7	,	,	,
cord-309582-ihrj84hr	124	8	especially	especially	RB
cord-309582-ihrj84hr	124	9	in	in	IN
cord-309582-ihrj84hr	124	10	countries	country	NNS
cord-309582-ihrj84hr	124	11	with	with	IN
cord-309582-ihrj84hr	124	12	limited	limited	JJ
cord-309582-ihrj84hr	124	13	resources	resource	NNS
cord-309582-ihrj84hr	124	14	as	as	RB
cord-309582-ihrj84hr	124	15	well	well	RB
cord-309582-ihrj84hr	124	16	as	as	IN
cord-309582-ihrj84hr	124	17	support	support	NN
cord-309582-ihrj84hr	124	18	and	and	CC
cord-309582-ihrj84hr	124	19	collaboration	collaboration	NN
cord-309582-ihrj84hr	124	20	from	from	IN
cord-309582-ihrj84hr	124	21	regulatory	regulatory	JJ
cord-309582-ihrj84hr	124	22	bodies	body	NNS
cord-309582-ihrj84hr	124	23	to	to	TO
cord-309582-ihrj84hr	124	24	ensure	ensure	VB
cord-309582-ihrj84hr	124	25	success	success	NN
cord-309582-ihrj84hr	124	26	[	[	-LRB-
cord-309582-ihrj84hr	124	27	28	28	CD
cord-309582-ihrj84hr	124	28	]	]	-RRB-
cord-309582-ihrj84hr	124	29	.	.	.
cord-309582-ihrj84hr	125	1	The	the	DT
cord-309582-ihrj84hr	125	2	rapid	rapid	JJ
cord-309582-ihrj84hr	125	3	action	action	NN
cord-309582-ihrj84hr	125	4	from	from	IN
cord-309582-ihrj84hr	125	5	concept	concept	NN
cord-309582-ihrj84hr	125	6	to	to	IN
cord-309582-ihrj84hr	125	7	implementation	implementation	NN
cord-309582-ihrj84hr	125	8	of	of	IN
cord-309582-ihrj84hr	125	9	clinical	clinical	JJ
cord-309582-ihrj84hr	125	10	studies	study	NNS
cord-309582-ihrj84hr	125	11	is	be	VBZ
cord-309582-ihrj84hr	125	12	crucial	crucial	JJ
cord-309582-ihrj84hr	125	13	during	during	IN
cord-309582-ihrj84hr	125	14	infectious	infectious	JJ
cord-309582-ihrj84hr	125	15	disease	disease	NN
cord-309582-ihrj84hr	125	16	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	125	17	.	.	.
cord-309582-ihrj84hr	126	1	This	this	DT
cord-309582-ihrj84hr	126	2	kind	kind	NN
cord-309582-ihrj84hr	126	3	of	of	IN
cord-309582-ihrj84hr	126	4	approach	approach	NN
cord-309582-ihrj84hr	126	5	will	will	MD
cord-309582-ihrj84hr	126	6	require	require	VB
cord-309582-ihrj84hr	126	7	innovative	innovative	JJ
cord-309582-ihrj84hr	126	8	research	research	NN
cord-309582-ihrj84hr	126	9	designs	design	NNS
cord-309582-ihrj84hr	126	10	such	such	JJ
cord-309582-ihrj84hr	126	11	as	as	IN
cord-309582-ihrj84hr	126	12	"	"	``
cord-309582-ihrj84hr	126	13	n	n	NNP
cord-309582-ihrj84hr	126	14	of	of	IN
cord-309582-ihrj84hr	126	15	1	1	CD
cord-309582-ihrj84hr	126	16	"	"	''
cord-309582-ihrj84hr	126	17	trials	trial	NNS
cord-309582-ihrj84hr	126	18	[	[	-LRB-
cord-309582-ihrj84hr	126	19	29	29	CD
cord-309582-ihrj84hr	126	20	]	]	-RRB-
cord-309582-ihrj84hr	126	21	adaptive	adaptive	JJ
cord-309582-ihrj84hr	126	22	platform	platform	NN
cord-309582-ihrj84hr	126	23	trials	trial	NNS
cord-309582-ihrj84hr	126	24	[	[	-LRB-
cord-309582-ihrj84hr	126	25	30	30	CD
cord-309582-ihrj84hr	126	26	]	]	-RRB-
cord-309582-ihrj84hr	126	27	,	,	,
cord-309582-ihrj84hr	126	28	or	or	CC
cord-309582-ihrj84hr	126	29	ring	ring	NN
cord-309582-ihrj84hr	126	30	vaccination	vaccination	NN
cord-309582-ihrj84hr	126	31	designs	design	NNS
cord-309582-ihrj84hr	126	32	[	[	-LRB-
cord-309582-ihrj84hr	126	33	31	31	CD
cord-309582-ihrj84hr	126	34	]	]	-RRB-
cord-309582-ihrj84hr	126	35	with	with	IN
cord-309582-ihrj84hr	126	36	pre	pre	JJ
cord-309582-ihrj84hr	126	37	-	-	JJ
cord-309582-ihrj84hr	126	38	outbreak	outbreak	JJ
cord-309582-ihrj84hr	126	39	approval	approval	NN
cord-309582-ihrj84hr	126	40	,	,	,
cord-309582-ihrj84hr	126	41	rapid	rapid	JJ
cord-309582-ihrj84hr	126	42	implementation	implementation	NN
cord-309582-ihrj84hr	126	43	and	and	CC
cord-309582-ihrj84hr	126	44	timely	timely	JJ
cord-309582-ihrj84hr	126	45	effective	effective	JJ
cord-309582-ihrj84hr	126	46	methods	method	NNS
cord-309582-ihrj84hr	126	47	of	of	IN
cord-309582-ihrj84hr	126	48	data	datum	NNS
cord-309582-ihrj84hr	126	49	exchange	exchange	NN
cord-309582-ihrj84hr	126	50	across	across	IN
cord-309582-ihrj84hr	126	51	global	global	JJ
cord-309582-ihrj84hr	126	52	collaborations	collaboration	NNS
cord-309582-ihrj84hr	126	53	.	.	.
cord-309582-ihrj84hr	127	1	Continuation	continuation	NN
cord-309582-ihrj84hr	127	2	of	of	IN
cord-309582-ihrj84hr	127	3	research	research	NN
cord-309582-ihrj84hr	127	4	on	on	IN
cord-309582-ihrj84hr	127	5	banked	banked	JJ
cord-309582-ihrj84hr	127	6	patient	patient	NN
cord-309582-ihrj84hr	127	7	materials	material	NNS
cord-309582-ihrj84hr	127	8	such	such	JJ
cord-309582-ihrj84hr	127	9	as	as	IN
cord-309582-ihrj84hr	127	10	fluids	fluid	NNS
cord-309582-ihrj84hr	127	11	and	and	CC
cord-309582-ihrj84hr	127	12	tissue	tissue	NN
cord-309582-ihrj84hr	127	13	samples	sample	NNS
cord-309582-ihrj84hr	127	14	collected	collect	VBN
cord-309582-ihrj84hr	127	15	during	during	IN
cord-309582-ihrj84hr	127	16	outbreaks	outbreak	NNS
cord-309582-ihrj84hr	127	17	after	after	IN
cord-309582-ihrj84hr	127	18	appropriate	appropriate	JJ
cord-309582-ihrj84hr	127	19	consent	consent	NN
cord-309582-ihrj84hr	127	20	will	will	MD
cord-309582-ihrj84hr	127	21	likely	likely	RB
cord-309582-ihrj84hr	127	22	further	far	RBR
cord-309582-ihrj84hr	127	23	enhance	enhance	VB
cord-309582-ihrj84hr	127	24	diagnostic	diagnostic	JJ
cord-309582-ihrj84hr	127	25	and	and	CC
cord-309582-ihrj84hr	127	26	therapeutic	therapeutic	JJ
cord-309582-ihrj84hr	127	27	discoveries	discovery	NNS
cord-309582-ihrj84hr	127	28	.	.	.
cord-309582-ihrj84hr	128	1	Studies	study	NNS
cord-309582-ihrj84hr	128	2	looking	look	VBG
cord-309582-ihrj84hr	128	3	at	at	IN
cord-309582-ihrj84hr	128	4	the	the	DT
cord-309582-ihrj84hr	128	5	long	long	JJ
cord-309582-ihrj84hr	128	6	term	term	NN
cord-309582-ihrj84hr	128	7	sequalae	sequalae	NNP
cord-309582-ihrj84hr	128	8	of	of	IN
cord-309582-ihrj84hr	128	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	128	10	are	be	VBP
cord-309582-ihrj84hr	128	11	also	also	RB
cord-309582-ihrj84hr	128	12	of	of	IN
cord-309582-ihrj84hr	128	13	importance	importance	NN
cord-309582-ihrj84hr	128	14	.	.	.
cord-309582-ihrj84hr	129	1	As	as	IN
cord-309582-ihrj84hr	129	2	recent	recent	JJ
cord-309582-ihrj84hr	129	3	publications	publication	NNS
cord-309582-ihrj84hr	129	4	describe	describe	VBP
cord-309582-ihrj84hr	129	5	multi	multi	JJ
cord-309582-ihrj84hr	129	6	-	-	JJ
cord-309582-ihrj84hr	129	7	organ	organ	JJ
cord-309582-ihrj84hr	129	8	involvement	involvement	NN
cord-309582-ihrj84hr	129	9	,	,	,
cord-309582-ihrj84hr	129	10	long	long	JJ
cord-309582-ihrj84hr	129	11	term	term	NN
cord-309582-ihrj84hr	129	12	follow	follow	NN
cord-309582-ihrj84hr	129	13	-	-	HYPH
cord-309582-ihrj84hr	129	14	up	up	NN
cord-309582-ihrj84hr	129	15	of	of	IN
cord-309582-ihrj84hr	129	16	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	129	17	survivors	survivor	NNS
cord-309582-ihrj84hr	129	18	can	can	MD
cord-309582-ihrj84hr	129	19	assist	assist	VB
cord-309582-ihrj84hr	129	20	in	in	IN
cord-309582-ihrj84hr	129	21	identifying	identify	VBG
cord-309582-ihrj84hr	129	22	possible	possible	JJ
cord-309582-ihrj84hr	129	23	physical	physical	JJ
cord-309582-ihrj84hr	129	24	and	and	CC
cord-309582-ihrj84hr	129	25	mental	mental	JJ
cord-309582-ihrj84hr	129	26	health	health	NN
cord-309582-ihrj84hr	129	27	sequellae	sequellae	NNS
cord-309582-ihrj84hr	129	28	.	.	.
cord-309582-ihrj84hr	130	1	Laboratory	laboratory	NN
cord-309582-ihrj84hr	130	2	based	base	VBN
cord-309582-ihrj84hr	130	3	research	research	NN
cord-309582-ihrj84hr	130	4	such	such	JJ
cord-309582-ihrj84hr	130	5	as	as	IN
cord-309582-ihrj84hr	130	6	life	life	NN
cord-309582-ihrj84hr	130	7	-	-	HYPH
cord-309582-ihrj84hr	130	8	saving	save	VBG
cord-309582-ihrj84hr	130	9	vaccines	vaccine	NNS
cord-309582-ihrj84hr	130	10	and	and	CC
cord-309582-ihrj84hr	130	11	therapies	therapy	NNS
cord-309582-ihrj84hr	130	12	,	,	,
cord-309582-ihrj84hr	130	13	particularly	particularly	RB
cord-309582-ihrj84hr	130	14	against	against	IN
cord-309582-ihrj84hr	130	15	the	the	DT
cord-309582-ihrj84hr	130	16	new	new	JJ
cord-309582-ihrj84hr	130	17	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	130	18	must	must	MD
cord-309582-ihrj84hr	130	19	continue	continue	VB
cord-309582-ihrj84hr	130	20	.	.	.
cord-309582-ihrj84hr	131	1	Cell	cell	NN
cord-309582-ihrj84hr	131	2	lines	line	NNS
cord-309582-ihrj84hr	131	3	research	research	NN
cord-309582-ihrj84hr	131	4	are	be	VBP
cord-309582-ihrj84hr	131	5	essential	essential	JJ
cord-309582-ihrj84hr	131	6	for	for	IN
cord-309582-ihrj84hr	131	7	the	the	DT
cord-309582-ihrj84hr	131	8	production	production	NN
cord-309582-ihrj84hr	131	9	of	of	IN
cord-309582-ihrj84hr	131	10	vaccines	vaccine	NNS
cord-309582-ihrj84hr	131	11	,	,	,
cord-309582-ihrj84hr	131	12	as	as	IN
cord-309582-ihrj84hr	131	13	are	be	VBP
cord-309582-ihrj84hr	131	14	testing	test	VBG
cord-309582-ihrj84hr	131	15	drug	drug	NN
cord-309582-ihrj84hr	131	16	metabolism	metabolism	NN
cord-309582-ihrj84hr	131	17	,	,	,
cord-309582-ihrj84hr	131	18	cytotoxicity	cytotoxicity	NN
cord-309582-ihrj84hr	131	19	and	and	CC
cord-309582-ihrj84hr	131	20	antibody	antibody	NN
cord-309582-ihrj84hr	131	21	production	production	NN
cord-309582-ihrj84hr	131	22	during	during	IN
cord-309582-ihrj84hr	131	23	a	a	DT
cord-309582-ihrj84hr	131	24	pandemic	pandemic	NN
cord-309582-ihrj84hr	131	25	[	[	-LRB-
cord-309582-ihrj84hr	131	26	32	32	CD
cord-309582-ihrj84hr	131	27	]	]	-RRB-
cord-309582-ihrj84hr	131	28	[	[	-LRB-
cord-309582-ihrj84hr	131	29	33	33	CD
cord-309582-ihrj84hr	131	30	]	]	-RRB-
cord-309582-ihrj84hr	131	31	[	[	-LRB-
cord-309582-ihrj84hr	131	32	34	34	CD
cord-309582-ihrj84hr	131	33	]	]	-RRB-
cord-309582-ihrj84hr	131	34	.	.	.
cord-309582-ihrj84hr	132	1	Maintenance	maintenance	NN
cord-309582-ihrj84hr	132	2	of	of	IN
cord-309582-ihrj84hr	132	3	cell	cell	NN
cord-309582-ihrj84hr	132	4	lines	line	NNS
cord-309582-ihrj84hr	132	5	requires	require	VBZ
cord-309582-ihrj84hr	132	6	uninterrupted	uninterrupted	JJ
cord-309582-ihrj84hr	132	7	examination	examination	NN
cord-309582-ihrj84hr	132	8	of	of	IN
cord-309582-ihrj84hr	132	9	cell	cell	NN
cord-309582-ihrj84hr	132	10	morphology	morphology	NN
cord-309582-ihrj84hr	132	11	and	and	CC
cord-309582-ihrj84hr	132	12	periodic	periodic	JJ
cord-309582-ihrj84hr	132	13	change	change	NN
cord-309582-ihrj84hr	132	14	of	of	IN
cord-309582-ihrj84hr	132	15	medium	medium	NN
cord-309582-ihrj84hr	132	16	[	[	-LRB-
cord-309582-ihrj84hr	132	17	35	35	CD
cord-309582-ihrj84hr	132	18	]	]	-RRB-
cord-309582-ihrj84hr	132	19	.	.	.
cord-309582-ihrj84hr	133	1	This	this	DT
cord-309582-ihrj84hr	133	2	kind	kind	NN
cord-309582-ihrj84hr	133	3	of	of	IN
cord-309582-ihrj84hr	133	4	maintenance	maintenance	NN
cord-309582-ihrj84hr	133	5	could	could	MD
cord-309582-ihrj84hr	133	6	be	be	VB
cord-309582-ihrj84hr	133	7	affected	affect	VBN
cord-309582-ihrj84hr	133	8	during	during	IN
cord-309582-ihrj84hr	133	9	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	133	10	pandemic	pandemic	NN
cord-309582-ihrj84hr	133	11	due	due	IN
cord-309582-ihrj84hr	133	12	to	to	IN
cord-309582-ihrj84hr	133	13	reduction	reduction	NN
cord-309582-ihrj84hr	133	14	of	of	IN
cord-309582-ihrj84hr	133	15	research	research	NN
cord-309582-ihrj84hr	133	16	laboratory	laboratory	NN
cord-309582-ihrj84hr	133	17	staff	staff	NN
cord-309582-ihrj84hr	133	18	and	and	CC
cord-309582-ihrj84hr	133	19	interruption	interruption	NN
cord-309582-ihrj84hr	133	20	in	in	IN
cord-309582-ihrj84hr	133	21	supply	supply	NN
cord-309582-ihrj84hr	133	22	chains	chain	NNS
cord-309582-ihrj84hr	133	23	.	.	.
cord-309582-ihrj84hr	134	1	Currently	currently	RB
cord-309582-ihrj84hr	134	2	,	,	,
cord-309582-ihrj84hr	134	3	millions	million	NNS
cord-309582-ihrj84hr	134	4	of	of	IN
cord-309582-ihrj84hr	134	5	animals	animal	NNS
cord-309582-ihrj84hr	134	6	are	be	VBP
cord-309582-ihrj84hr	134	7	used	use	VBN
cord-309582-ihrj84hr	134	8	in	in	IN
cord-309582-ihrj84hr	134	9	research	research	NN
cord-309582-ihrj84hr	134	10	laboratories	laboratory	NNS
cord-309582-ihrj84hr	134	11	around	around	IN
cord-309582-ihrj84hr	134	12	the	the	DT
cord-309582-ihrj84hr	134	13	globe	globe	NN
cord-309582-ihrj84hr	134	14	[	[	-LRB-
cord-309582-ihrj84hr	134	15	36	36	CD
cord-309582-ihrj84hr	134	16	]	]	-RRB-
cord-309582-ihrj84hr	134	17	.	.	.
cord-309582-ihrj84hr	135	1	Indeed	indeed	RB
cord-309582-ihrj84hr	135	2	,	,	,
cord-309582-ihrj84hr	135	3	animals	animal	NNS
cord-309582-ihrj84hr	135	4	need	need	VBP
cord-309582-ihrj84hr	135	5	to	to	TO
cord-309582-ihrj84hr	135	6	be	be	VB
cord-309582-ihrj84hr	135	7	looked	look	VBN
cord-309582-ihrj84hr	135	8	after	after	IN
cord-309582-ihrj84hr	135	9	,	,	,
cord-309582-ihrj84hr	135	10	and	and	CC
cord-309582-ihrj84hr	135	11	breeding	breed	VBG
cord-309582-ihrj84hr	135	12	lines	line	NNS
cord-309582-ihrj84hr	135	13	must	must	MD
cord-309582-ihrj84hr	135	14	be	be	VB
cord-309582-ihrj84hr	135	15	kept	keep	VBN
cord-309582-ihrj84hr	135	16	intact	intact	JJ
cord-309582-ihrj84hr	135	17	.	.	.
cord-309582-ihrj84hr	136	1	However	however	RB
cord-309582-ihrj84hr	136	2	,	,	,
cord-309582-ihrj84hr	136	3	in	in	IN
cord-309582-ihrj84hr	136	4	some	some	DT
cord-309582-ihrj84hr	136	5	laboratories	laboratory	NNS
cord-309582-ihrj84hr	136	6	the	the	DT
cord-309582-ihrj84hr	136	7	work	work	NN
cord-309582-ihrj84hr	136	8	force	force	NN
cord-309582-ihrj84hr	136	9	has	have	VBZ
cord-309582-ihrj84hr	136	10	been	be	VBN
cord-309582-ihrj84hr	136	11	reduced	reduce	VBN
cord-309582-ihrj84hr	136	12	with	with	IN
cord-309582-ihrj84hr	136	13	researchers	researcher	NNS
cord-309582-ihrj84hr	136	14	asked	ask	VBD
cord-309582-ihrj84hr	136	15	to	to	TO
cord-309582-ihrj84hr	136	16	stay	stay	VB
cord-309582-ihrj84hr	136	17	away	away	RB
cord-309582-ihrj84hr	136	18	from	from	IN
cord-309582-ihrj84hr	136	19	their	-PRON-	PRP$
cord-309582-ihrj84hr	136	20	laboratories	laboratory	NNS
cord-309582-ihrj84hr	136	21	to	to	TO
cord-309582-ihrj84hr	136	22	minimize	minimize	VB
cord-309582-ihrj84hr	136	23	their	-PRON-	PRP$
cord-309582-ihrj84hr	136	24	risk	risk	NN
cord-309582-ihrj84hr	136	25	of	of	IN
cord-309582-ihrj84hr	136	26	exposure	exposure	NN
cord-309582-ihrj84hr	136	27	to	to	IN
cord-309582-ihrj84hr	136	28	SARS	SARS	NNP
cord-309582-ihrj84hr	136	29	-	-	HYPH
cord-309582-ihrj84hr	136	30	COV-2	COV-2	NNP
cord-309582-ihrj84hr	136	31	.	.	.
cord-309582-ihrj84hr	137	1	These	these	DT
cord-309582-ihrj84hr	137	2	understandable	understandable	JJ
cord-309582-ihrj84hr	137	3	measures	measure	NNS
cord-309582-ihrj84hr	137	4	have	have	VBP
cord-309582-ihrj84hr	137	5	nonetheless	nonetheless	RB
cord-309582-ihrj84hr	137	6	affected	affect	VBN
cord-309582-ihrj84hr	137	7	the	the	DT
cord-309582-ihrj84hr	137	8	care	care	NN
cord-309582-ihrj84hr	137	9	and	and	CC
cord-309582-ihrj84hr	137	10	wellbeing	wellbeing	NN
cord-309582-ihrj84hr	137	11	of	of	IN
cord-309582-ihrj84hr	137	12	experimental	experimental	JJ
cord-309582-ihrj84hr	137	13	animals	animal	NNS
cord-309582-ihrj84hr	137	14	.	.	.
cord-309582-ihrj84hr	138	1	Some	some	DT
cord-309582-ihrj84hr	138	2	researchers	researcher	NNS
cord-309582-ihrj84hr	138	3	were	be	VBD
cord-309582-ihrj84hr	138	4	even	even	RB
cord-309582-ihrj84hr	138	5	asked	ask	VBN
cord-309582-ihrj84hr	138	6	to	to	TO
cord-309582-ihrj84hr	138	7	dispose	dispose	VB
cord-309582-ihrj84hr	138	8	of	of	IN
cord-309582-ihrj84hr	138	9	animals	animal	NNS
cord-309582-ihrj84hr	138	10	while	while	IN
cord-309582-ihrj84hr	138	11	others	other	NNS
cord-309582-ihrj84hr	138	12	had	have	VBD
cord-309582-ihrj84hr	138	13	to	to	TO
cord-309582-ihrj84hr	138	14	interrupt	interrupt	VB
cord-309582-ihrj84hr	138	15	their	-PRON-	PRP$
cord-309582-ihrj84hr	138	16	research	research	NN
cord-309582-ihrj84hr	138	17	in	in	IN
cord-309582-ihrj84hr	138	18	a	a	DT
cord-309582-ihrj84hr	138	19	way	way	NN
cord-309582-ihrj84hr	138	20	that	that	WDT
cord-309582-ihrj84hr	138	21	will	will	MD
cord-309582-ihrj84hr	138	22	likely	likely	RB
cord-309582-ihrj84hr	138	23	require	require	VB
cord-309582-ihrj84hr	138	24	the	the	DT
cord-309582-ihrj84hr	138	25	use	use	NN
cord-309582-ihrj84hr	138	26	of	of	IN
cord-309582-ihrj84hr	138	27	another	another	DT
cord-309582-ihrj84hr	138	28	animals	animal	NNS
cord-309582-ihrj84hr	138	29	once	once	RB
cord-309582-ihrj84hr	138	30	back	back	RB
cord-309582-ihrj84hr	138	31	to	to	IN
cord-309582-ihrj84hr	138	32	work	work	NN
cord-309582-ihrj84hr	138	33	[	[	-LRB-
cord-309582-ihrj84hr	138	34	37	37	CD
cord-309582-ihrj84hr	138	35	]	]	-RRB-
cord-309582-ihrj84hr	138	36	.	.	.
cord-309582-ihrj84hr	139	1	To	to	TO
cord-309582-ihrj84hr	139	2	minimize	minimize	VB
cord-309582-ihrj84hr	139	3	the	the	DT
cord-309582-ihrj84hr	139	4	impact	impact	NN
cord-309582-ihrj84hr	139	5	of	of	IN
cord-309582-ihrj84hr	139	6	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	139	7	on	on	IN
cord-309582-ihrj84hr	139	8	laboratory	laboratory	NN
cord-309582-ihrj84hr	139	9	-	-	HYPH
cord-309582-ihrj84hr	139	10	based	base	VBN
cord-309582-ihrj84hr	139	11	research	research	NN
cord-309582-ihrj84hr	139	12	,	,	,
cord-309582-ihrj84hr	139	13	researchers	researcher	NNS
cord-309582-ihrj84hr	139	14	should	should	MD
cord-309582-ihrj84hr	139	15	follow	follow	VB
cord-309582-ihrj84hr	139	16	local	local	JJ
cord-309582-ihrj84hr	139	17	institutions	institution	NNS
cord-309582-ihrj84hr	139	18	'	'	POS
cord-309582-ihrj84hr	139	19	safety	safety	NN
cord-309582-ihrj84hr	139	20	regulations	regulation	NNS
cord-309582-ihrj84hr	139	21	.	.	.
cord-309582-ihrj84hr	140	1	Many	many	JJ
cord-309582-ihrj84hr	140	2	laboratory	laboratory	NN
cord-309582-ihrj84hr	140	3	-	-	HYPH
cord-309582-ihrj84hr	140	4	based	base	VBN
cord-309582-ihrj84hr	140	5	research	research	NN
cord-309582-ihrj84hr	140	6	institutions	institution	NNS
cord-309582-ihrj84hr	140	7	have	have	VBP
cord-309582-ihrj84hr	140	8	established	establish	VBN
cord-309582-ihrj84hr	140	9	new	new	JJ
cord-309582-ihrj84hr	140	10	regulation	regulation	NN
cord-309582-ihrj84hr	140	11	to	to	TO
cord-309582-ihrj84hr	140	12	ensure	ensure	VB
cord-309582-ihrj84hr	140	13	safety	safety	NN
cord-309582-ihrj84hr	140	14	of	of	IN
cord-309582-ihrj84hr	140	15	investigators	investigator	NNS
cord-309582-ihrj84hr	140	16	and	and	CC
cord-309582-ihrj84hr	140	17	continuity	continuity	NN
cord-309582-ihrj84hr	140	18	of	of	IN
cord-309582-ihrj84hr	140	19	work	work	NN
cord-309582-ihrj84hr	140	20	[	[	-LRB-
cord-309582-ihrj84hr	140	21	38	38	CD
cord-309582-ihrj84hr	140	22	]	]	-RRB-
cord-309582-ihrj84hr	140	23	.	.	.
cord-309582-ihrj84hr	141	1	Some	some	DT
cord-309582-ihrj84hr	141	2	of	of	IN
cord-309582-ihrj84hr	141	3	these	these	DT
cord-309582-ihrj84hr	141	4	new	new	JJ
cord-309582-ihrj84hr	141	5	regulations	regulation	NNS
cord-309582-ihrj84hr	141	6	include	include	VBP
cord-309582-ihrj84hr	141	7	reducing	reduce	VBG
cord-309582-ihrj84hr	141	8	laboratory	laboratory	NN
cord-309582-ihrj84hr	141	9	workforce	workforce	NN
cord-309582-ihrj84hr	141	10	to	to	IN
cord-309582-ihrj84hr	141	11	those	those	DT
cord-309582-ihrj84hr	141	12	conducting	conduct	VBG
cord-309582-ihrj84hr	141	13	essential	essential	JJ
cord-309582-ihrj84hr	141	14	work	work	NN
cord-309582-ihrj84hr	141	15	,	,	,
cord-309582-ihrj84hr	141	16	establishing	establish	VBG
cord-309582-ihrj84hr	141	17	a	a	DT
cord-309582-ihrj84hr	141	18	system	system	NN
cord-309582-ihrj84hr	141	19	of	of	IN
cord-309582-ihrj84hr	141	20	reporting	report	VBG
cord-309582-ihrj84hr	141	21	symptoms	symptom	NNS
cord-309582-ihrj84hr	141	22	and	and	CC
cord-309582-ihrj84hr	141	23	signs	sign	NNS
cord-309582-ihrj84hr	141	24	suggestive	suggestive	JJ
cord-309582-ihrj84hr	141	25	of	of	IN
cord-309582-ihrj84hr	141	26	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	141	27	,	,	,
cord-309582-ihrj84hr	141	28	working	work	VBG
cord-309582-ihrj84hr	141	29	in	in	IN
cord-309582-ihrj84hr	141	30	small	small	JJ
cord-309582-ihrj84hr	141	31	groups	group	NNS
cord-309582-ihrj84hr	141	32	and	and	CC
cord-309582-ihrj84hr	141	33	keeping	keep	VBG
cord-309582-ihrj84hr	141	34	a	a	DT
cord-309582-ihrj84hr	141	35	distance	distance	NN
cord-309582-ihrj84hr	141	36	of	of	IN
cord-309582-ihrj84hr	141	37	at	at	RB
cord-309582-ihrj84hr	141	38	least	least	RBS
cord-309582-ihrj84hr	141	39	two	two	CD
cord-309582-ihrj84hr	141	40	meters	meter	NNS
cord-309582-ihrj84hr	141	41	between	between	IN
cord-309582-ihrj84hr	141	42	staff	staff	NN
cord-309582-ihrj84hr	141	43	while	while	IN
cord-309582-ihrj84hr	141	44	also	also	RB
cord-309582-ihrj84hr	141	45	implementing	implement	VBG
cord-309582-ihrj84hr	141	46	working	working	NN
cord-309582-ihrj84hr	141	47	shifts	shift	NNS
cord-309582-ihrj84hr	141	48	.	.	.
cord-309582-ihrj84hr	141	49	 	 	_SP
cord-309582-ihrj84hr	142	1	The	the	DT
cord-309582-ihrj84hr	142	2	WHO	WHO	NNP
cord-309582-ihrj84hr	143	1	R&D	R&D	NNP
cord-309582-ihrj84hr	143	2	Blueprint	Blueprint	NNP
cord-309582-ihrj84hr	143	3	:	:	:
cord-309582-ihrj84hr	144	1	2018	2018	CD
cord-309582-ihrj84hr	144	2	review	review	NN
cord-309582-ihrj84hr	144	3	of	of	IN
cord-309582-ihrj84hr	144	4	emerging	emerge	VBG
cord-309582-ihrj84hr	144	5	infectious	infectious	JJ
cord-309582-ihrj84hr	144	6	diseases	disease	NNS
cord-309582-ihrj84hr	144	7	requiring	require	VBG
cord-309582-ihrj84hr	144	8	urgent	urgent	JJ
cord-309582-ihrj84hr	144	9	research	research	NN
cord-309582-ihrj84hr	144	10	and	and	CC
cord-309582-ihrj84hr	144	11	development	development	NN
cord-309582-ihrj84hr	144	12	efforts	effort	NNS
cord-309582-ihrj84hr	145	1	Sustained	sustained	JJ
cord-309582-ihrj84hr	145	2	research	research	NN
cord-309582-ihrj84hr	145	3	fund	fund	NN
cord-309582-ihrj84hr	145	4	and	and	CC
cord-309582-ihrj84hr	145	5	dedicated	dedicated	JJ
cord-309582-ihrj84hr	145	6	research	research	NN
cord-309582-ihrj84hr	145	7	center	center	NN
cord-309582-ihrj84hr	145	8	for	for	IN
cord-309582-ihrj84hr	145	9	preparing	prepare	VBG
cord-309582-ihrj84hr	145	10	next	next	JJ
cord-309582-ihrj84hr	145	11	pandemic	pandemic	NN
cord-309582-ihrj84hr	145	12	,	,	,
cord-309582-ihrj84hr	145	13	Precision	Precision	NNP
cord-309582-ihrj84hr	145	14	Clinical	Clinical	NNP
cord-309582-ihrj84hr	145	15	Medicine	Medicine	NNP
cord-309582-ihrj84hr	145	16	,	,	,
cord-309582-ihrj84hr	146	1	pbaa012	pbaa012	NNP
cord-309582-ihrj84hr	146	2	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	146	3	:	:	:
cord-309582-ihrj84hr	146	4	an	an	DT
cord-309582-ihrj84hr	146	5	Emerging	emerge	VBG
cord-309582-ihrj84hr	146	6	Coronavirus	Coronavirus	NNP
cord-309582-ihrj84hr	146	7	that	that	WDT
cord-309582-ihrj84hr	146	8	Causes	cause	VBZ
cord-309582-ihrj84hr	146	9	a	a	DT
cord-309582-ihrj84hr	146	10	Global	Global	NNP
cord-309582-ihrj84hr	146	11	Threat	threat	NN
cord-309582-ihrj84hr	147	1	The	the	DT
cord-309582-ihrj84hr	147	2	global	global	JJ
cord-309582-ihrj84hr	147	3	battle	battle	NN
cord-309582-ihrj84hr	147	4	against	against	IN
cord-309582-ihrj84hr	147	5	SARS	SARS	NNP
cord-309582-ihrj84hr	147	6	-	-	HYPH
cord-309582-ihrj84hr	147	7	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	147	8	and	and	CC
cord-309582-ihrj84hr	147	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	147	10	Real	real	JJ
cord-309582-ihrj84hr	147	11	estimates	estimate	NNS
cord-309582-ihrj84hr	147	12	of	of	IN
cord-309582-ihrj84hr	147	13	mortality	mortality	NN
cord-309582-ihrj84hr	147	14	following	follow	VBG
cord-309582-ihrj84hr	147	15	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	147	16	infection	infection	NN
cord-309582-ihrj84hr	148	1	The	the	DT
cord-309582-ihrj84hr	148	2	epidemiology	epidemiology	NN
cord-309582-ihrj84hr	148	3	and	and	CC
cord-309582-ihrj84hr	148	4	pathogenesis	pathogenesis	NN
cord-309582-ihrj84hr	148	5	of	of	IN
cord-309582-ihrj84hr	148	6	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	148	7	disease	disease	NN
cord-309582-ihrj84hr	148	8	(	(	-LRB-
cord-309582-ihrj84hr	148	9	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	148	10	)	)	-RRB-
cord-309582-ihrj84hr	148	11	outbreak	outbreak	NN
cord-309582-ihrj84hr	149	1	The	the	DT
cord-309582-ihrj84hr	149	2	origin	origin	NN
cord-309582-ihrj84hr	149	3	,	,	,
cord-309582-ihrj84hr	149	4	transmission	transmission	NN
cord-309582-ihrj84hr	149	5	and	and	CC
cord-309582-ihrj84hr	149	6	clinical	clinical	JJ
cord-309582-ihrj84hr	149	7	therapies	therapy	NNS
cord-309582-ihrj84hr	149	8	on	on	IN
cord-309582-ihrj84hr	149	9	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	149	10	disease	disease	NN
cord-309582-ihrj84hr	149	11	2019	2019	CD
cord-309582-ihrj84hr	149	12	(	(	-LRB-
cord-309582-ihrj84hr	149	13	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	149	14	)	)	-RRB-
cord-309582-ihrj84hr	149	15	outbreak	outbreak	NN
cord-309582-ihrj84hr	149	16	-an	-an	CD
cord-309582-ihrj84hr	149	17	update	update	NN
cord-309582-ihrj84hr	149	18	on	on	IN
cord-309582-ihrj84hr	149	19	the	the	DT
cord-309582-ihrj84hr	149	20	status	status	NN
cord-309582-ihrj84hr	149	21	Clinical	clinical	JJ
cord-309582-ihrj84hr	149	22	predictors	predictor	NNS
cord-309582-ihrj84hr	149	23	of	of	IN
cord-309582-ihrj84hr	149	24	mortality	mortality	NN
cord-309582-ihrj84hr	149	25	due	due	IN
cord-309582-ihrj84hr	149	26	to	to	IN
cord-309582-ihrj84hr	149	27	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	149	28	based	base	VBN
cord-309582-ihrj84hr	149	29	on	on	IN
cord-309582-ihrj84hr	149	30	an	an	DT
cord-309582-ihrj84hr	149	31	analysis	analysis	NN
cord-309582-ihrj84hr	149	32	of	of	IN
cord-309582-ihrj84hr	149	33	data	datum	NNS
cord-309582-ihrj84hr	149	34	of	of	IN
cord-309582-ihrj84hr	149	35	150	150	CD
cord-309582-ihrj84hr	149	36	patients	patient	NNS
cord-309582-ihrj84hr	149	37	from	from	IN
cord-309582-ihrj84hr	149	38	Wuhan	Wuhan	NNP
cord-309582-ihrj84hr	149	39	,	,	,
cord-309582-ihrj84hr	150	1	China	China	NNP
cord-309582-ihrj84hr	150	2	Breakthrough	Breakthrough	NNP
cord-309582-ihrj84hr	150	3	:	:	:
cord-309582-ihrj84hr	150	4	Chloroquine	chloroquine	NN
cord-309582-ihrj84hr	150	5	phosphate	phosphate	NN
cord-309582-ihrj84hr	150	6	has	have	VBZ
cord-309582-ihrj84hr	150	7	shown	show	VBN
cord-309582-ihrj84hr	150	8	apparent	apparent	JJ
cord-309582-ihrj84hr	150	9	efficacy	efficacy	NN
cord-309582-ihrj84hr	150	10	in	in	IN
cord-309582-ihrj84hr	150	11	treatment	treatment	NN
cord-309582-ihrj84hr	150	12	of	of	IN
cord-309582-ihrj84hr	150	13	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	150	14	associated	associated	JJ
cord-309582-ihrj84hr	150	15	pneumonia	pneumonia	NN
cord-309582-ihrj84hr	150	16	in	in	IN
cord-309582-ihrj84hr	150	17	clinical	clinical	JJ
cord-309582-ihrj84hr	150	18	studies	study	NNS
cord-309582-ihrj84hr	150	19	Efficacy	Efficacy	NNP
cord-309582-ihrj84hr	150	20	of	of	IN
cord-309582-ihrj84hr	150	21	hydroxychloroquine	hydroxychloroquine	NN
cord-309582-ihrj84hr	150	22	in	in	IN
cord-309582-ihrj84hr	150	23	patients	patient	NNS
cord-309582-ihrj84hr	150	24	with	with	IN
cord-309582-ihrj84hr	150	25	COVID-19	covid-19	NN
cord-309582-ihrj84hr	150	26	:	:	:
cord-309582-ihrj84hr	150	27	results	result	NNS
cord-309582-ihrj84hr	150	28	of	of	IN
cord-309582-ihrj84hr	150	29	a	a	DT
cord-309582-ihrj84hr	150	30	randomized	randomized	JJ
cord-309582-ihrj84hr	150	31	clinical	clinical	JJ
cord-309582-ihrj84hr	150	32	trial	trial	NN
cord-309582-ihrj84hr	150	33	Hydroxychloroquine	Hydroxychloroquine	NNP
cord-309582-ihrj84hr	150	34	and	and	CC
cord-309582-ihrj84hr	150	35	azithromycin	azithromycin	NNP
cord-309582-ihrj84hr	150	36	as	as	IN
cord-309582-ihrj84hr	150	37	a	a	DT
cord-309582-ihrj84hr	150	38	treatment	treatment	NN
cord-309582-ihrj84hr	150	39	of	of	IN
cord-309582-ihrj84hr	150	40	COVID-19	covid-19	NN
cord-309582-ihrj84hr	150	41	:	:	:
cord-309582-ihrj84hr	150	42	results	result	NNS
cord-309582-ihrj84hr	150	43	of	of	IN
cord-309582-ihrj84hr	150	44	an	an	DT
cord-309582-ihrj84hr	150	45	open	open	JJ
cord-309582-ihrj84hr	150	46	-	-	HYPH
cord-309582-ihrj84hr	150	47	label	label	NN
cord-309582-ihrj84hr	150	48	non	non	JJ
cord-309582-ihrj84hr	150	49	-	-	JJ
cord-309582-ihrj84hr	150	50	randomized	randomized	JJ
cord-309582-ihrj84hr	150	51	clinical	clinical	JJ
cord-309582-ihrj84hr	150	52	trial	trial	NN
cord-309582-ihrj84hr	150	53	Remdesivir	Remdesivir	NNP
cord-309582-ihrj84hr	150	54	and	and	CC
cord-309582-ihrj84hr	150	55	chloroquine	chloroquine	NN
cord-309582-ihrj84hr	150	56	effectively	effectively	RB
cord-309582-ihrj84hr	150	57	inhibit	inhibit	VBP
cord-309582-ihrj84hr	150	58	the	the	DT
cord-309582-ihrj84hr	150	59	recently	recently	RB
cord-309582-ihrj84hr	150	60	emerged	emerge	VBN
cord-309582-ihrj84hr	150	61	novel	novel	JJ
cord-309582-ihrj84hr	150	62	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	150	63	(	(	-LRB-
cord-309582-ihrj84hr	150	64	2019-nCoV	2019-ncov	CD
cord-309582-ihrj84hr	150	65	)	)	-RRB-
cord-309582-ihrj84hr	150	66	in	in	IN
cord-309582-ihrj84hr	150	67	vitro	vitro	FW
cord-309582-ihrj84hr	150	68	Therapeutic	therapeutic	JJ
cord-309582-ihrj84hr	150	69	options	option	NNS
cord-309582-ihrj84hr	150	70	for	for	IN
cord-309582-ihrj84hr	150	71	the	the	DT
cord-309582-ihrj84hr	150	72	2019	2019	CD
cord-309582-ihrj84hr	150	73	novel	novel	NN
cord-309582-ihrj84hr	150	74	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	150	75	(	(	-LRB-
cord-309582-ihrj84hr	150	76	2019-nCoV	2019-ncov	CD
cord-309582-ihrj84hr	150	77	)	)	-RRB-
cord-309582-ihrj84hr	150	78	Tocilizumab	Tocilizumab	NNP
cord-309582-ihrj84hr	150	79	,	,	,
cord-309582-ihrj84hr	150	80	an	an	DT
cord-309582-ihrj84hr	150	81	anti	anti	JJ
cord-309582-ihrj84hr	150	82	-	-	JJ
cord-309582-ihrj84hr	150	83	IL-6	il-6	JJ
cord-309582-ihrj84hr	150	84	receptor	receptor	NN
cord-309582-ihrj84hr	150	85	antibody	antibody	NN
cord-309582-ihrj84hr	150	86	,	,	,
cord-309582-ihrj84hr	150	87	to	to	TO
cord-309582-ihrj84hr	150	88	treat	treat	VB
cord-309582-ihrj84hr	150	89	COVID-19-related	covid-19-related	JJ
cord-309582-ihrj84hr	150	90	respiratory	respiratory	JJ
cord-309582-ihrj84hr	150	91	failure	failure	NN
cord-309582-ihrj84hr	150	92	:	:	:
cord-309582-ihrj84hr	150	93	a	a	DT
cord-309582-ihrj84hr	150	94	case	case	NN
cord-309582-ihrj84hr	150	95	report	report	NN
cord-309582-ihrj84hr	150	96	Preserving	preserve	VBG
cord-309582-ihrj84hr	150	97	Clinical	Clinical	NNP
cord-309582-ihrj84hr	150	98	Trial	Trial	NNP
cord-309582-ihrj84hr	150	99	Integrity	Integrity	NNP
cord-309582-ihrj84hr	150	100	During	during	IN
cord-309582-ihrj84hr	150	101	the	the	DT
cord-309582-ihrj84hr	150	102	Coronavirus	Coronavirus	NNP
cord-309582-ihrj84hr	150	103	Pandemic	Pandemic	NNP
cord-309582-ihrj84hr	150	104	Implementation	Implementation	NNP
cord-309582-ihrj84hr	150	105	of	of	IN
cord-309582-ihrj84hr	150	106	an	an	DT
cord-309582-ihrj84hr	150	107	Ebola	Ebola	NNP
cord-309582-ihrj84hr	150	108	virus	virus	NN
cord-309582-ihrj84hr	150	109	disease	disease	NN
cord-309582-ihrj84hr	150	110	vaccine	vaccine	NN
cord-309582-ihrj84hr	150	111	clinical	clinical	JJ
cord-309582-ihrj84hr	150	112	trial	trial	NN
cord-309582-ihrj84hr	150	113	during	during	IN
cord-309582-ihrj84hr	150	114	the	the	DT
cord-309582-ihrj84hr	150	115	Ebola	Ebola	NNP
cord-309582-ihrj84hr	150	116	epidemic	epidemic	NN
cord-309582-ihrj84hr	150	117	in	in	IN
cord-309582-ihrj84hr	150	118	Liberia	Liberia	NNP
cord-309582-ihrj84hr	150	119	:	:	:
cord-309582-ihrj84hr	150	120	Design	Design	NNP
cord-309582-ihrj84hr	150	121	,	,	,
cord-309582-ihrj84hr	150	122	procedures	procedure	NNS
cord-309582-ihrj84hr	150	123	,	,	,
cord-309582-ihrj84hr	150	124	and	and	CC
cord-309582-ihrj84hr	150	125	challenges	challenge	VBZ
cord-309582-ihrj84hr	150	126	Schuchat	Schuchat	NNP
cord-309582-ihrj84hr	150	127	A	A	NNP
cord-309582-ihrj84hr	150	128	;	;	:
cord-309582-ihrj84hr	150	129	STRIVE	strive	VB
cord-309582-ihrj84hr	150	130	Study	Study	NNP
cord-309582-ihrj84hr	150	131	Team	Team	NNP
cord-309582-ihrj84hr	150	132	.	.	.
cord-309582-ihrj84hr	151	1	The	the	DT
cord-309582-ihrj84hr	151	2	Sierra	Sierra	NNP
cord-309582-ihrj84hr	151	3	Leone	Leone	NNP
cord-309582-ihrj84hr	151	4	Trial	Trial	NNP
cord-309582-ihrj84hr	151	5	to	to	TO
cord-309582-ihrj84hr	151	6	Introduce	introduce	VB
cord-309582-ihrj84hr	151	7	a	a	DT
cord-309582-ihrj84hr	151	8	Vaccine	vaccine	NN
cord-309582-ihrj84hr	151	9	Against	against	IN
cord-309582-ihrj84hr	151	10	Ebola	Ebola	NNP
cord-309582-ihrj84hr	151	11	:	:	:
cord-309582-ihrj84hr	152	1	An	an	DT
cord-309582-ihrj84hr	152	2	Evaluation	Evaluation	NNP
cord-309582-ihrj84hr	152	3	of	of	IN
cord-309582-ihrj84hr	152	4	rVSV∆G	rVSV∆G	NNS
cord-309582-ihrj84hr	152	5	-	-	HYPH
cord-309582-ihrj84hr	152	6	ZEBOV	ZEBOV	NNP
cord-309582-ihrj84hr	152	7	-	-	HYPH
cord-309582-ihrj84hr	152	8	GP	GP	NNP
cord-309582-ihrj84hr	152	9	Vaccine	Vaccine	NNP
cord-309582-ihrj84hr	152	10	Tolerability	Tolerability	NNP
cord-309582-ihrj84hr	152	11	and	and	CC
cord-309582-ihrj84hr	152	12	Safety	Safety	NNP
cord-309582-ihrj84hr	152	13	During	during	IN
cord-309582-ihrj84hr	152	14	the	the	DT
cord-309582-ihrj84hr	152	15	West	West	NNP
cord-309582-ihrj84hr	152	16	Africa	Africa	NNP
cord-309582-ihrj84hr	152	17	Ebola	Ebola	NNP
cord-309582-ihrj84hr	152	18	Outbreak	Outbreak	NNP
cord-309582-ihrj84hr	152	19	Chloroquine	Chloroquine	NNP
cord-309582-ihrj84hr	152	20	diphosphate	diphosphate	JJ
cord-309582-ihrj84hr	152	21	in	in	IN
cord-309582-ihrj84hr	152	22	two	two	CD
cord-309582-ihrj84hr	152	23	different	different	JJ
cord-309582-ihrj84hr	152	24	dosages	dosage	NNS
cord-309582-ihrj84hr	152	25	as	as	IN
cord-309582-ihrj84hr	152	26	adjunctive	adjunctive	JJ
cord-309582-ihrj84hr	152	27	therapy	therapy	NN
cord-309582-ihrj84hr	152	28	of	of	IN
cord-309582-ihrj84hr	152	29	hospitalized	hospitalize	VBN
cord-309582-ihrj84hr	152	30	patients	patient	NNS
cord-309582-ihrj84hr	152	31	with	with	IN
cord-309582-ihrj84hr	152	32	severe	severe	JJ
cord-309582-ihrj84hr	152	33	respiratory	respiratory	JJ
cord-309582-ihrj84hr	152	34	syndrome	syndrome	NN
cord-309582-ihrj84hr	152	35	in	in	IN
cord-309582-ihrj84hr	152	36	the	the	DT
cord-309582-ihrj84hr	152	37	context	context	NN
cord-309582-ihrj84hr	152	38	of	of	IN
cord-309582-ihrj84hr	152	39	coronavirus	coronavirus	NN
cord-309582-ihrj84hr	152	40	(	(	-LRB-
cord-309582-ihrj84hr	152	41	SARS	SARS	NNP
cord-309582-ihrj84hr	152	42	-	-	HYPH
cord-309582-ihrj84hr	152	43	CoV-2	CoV-2	NNP
cord-309582-ihrj84hr	152	44	)	)	-RRB-
cord-309582-ihrj84hr	152	45	infection	infection	NN
cord-309582-ihrj84hr	152	46	:	:	:
cord-309582-ihrj84hr	152	47	Preliminary	preliminary	JJ
cord-309582-ihrj84hr	152	48	safety	safety	NN
cord-309582-ihrj84hr	152	49	results	result	NNS
cord-309582-ihrj84hr	152	50	of	of	IN
cord-309582-ihrj84hr	152	51	a	a	DT
cord-309582-ihrj84hr	152	52	randomized	randomized	JJ
cord-309582-ihrj84hr	152	53	,	,	,
cord-309582-ihrj84hr	152	54	double	double	JJ
cord-309582-ihrj84hr	152	55	-	-	HYPH
cord-309582-ihrj84hr	152	56	blinded	blinded	JJ
cord-309582-ihrj84hr	152	57	,	,	,
cord-309582-ihrj84hr	152	58	phase	phase	NN
cord-309582-ihrj84hr	152	59	IIb	iib	JJ
cord-309582-ihrj84hr	152	60	clinical	clinical	JJ
cord-309582-ihrj84hr	152	61	trial	trial	NN
cord-309582-ihrj84hr	152	62	(	(	-LRB-
cord-309582-ihrj84hr	152	63	CloroCovid-19	CloroCovid-19	NNP
cord-309582-ihrj84hr	152	64	Study	Study	NNP
cord-309582-ihrj84hr	152	65	)	)	-RRB-
cord-309582-ihrj84hr	153	1	A	a	DT
cord-309582-ihrj84hr	153	2	comparative	comparative	JJ
cord-309582-ihrj84hr	153	3	analysis	analysis	NN
cord-309582-ihrj84hr	153	4	of	of	IN
cord-309582-ihrj84hr	153	5	moral	moral	JJ
cord-309582-ihrj84hr	153	6	principles	principle	NNS
cord-309582-ihrj84hr	153	7	and	and	CC
cord-309582-ihrj84hr	153	8	behavioral	behavioral	JJ
cord-309582-ihrj84hr	153	9	norms	norm	NNS
cord-309582-ihrj84hr	153	10	in	in	IN
cord-309582-ihrj84hr	153	11	eight	eight	CD
cord-309582-ihrj84hr	153	12	ethical	ethical	JJ
cord-309582-ihrj84hr	153	13	codes	code	NNS
cord-309582-ihrj84hr	153	14	relevant	relevant	JJ
cord-309582-ihrj84hr	153	15	to	to	IN
cord-309582-ihrj84hr	153	16	health	health	NN
cord-309582-ihrj84hr	153	17	sciences	science	NNS
cord-309582-ihrj84hr	153	18	librarianship	librarianship	NN
cord-309582-ihrj84hr	153	19	,	,	,
cord-309582-ihrj84hr	153	20	medical	medical	JJ
cord-309582-ihrj84hr	153	21	informatics	informatics	NN
cord-309582-ihrj84hr	153	22	,	,	,
cord-309582-ihrj84hr	153	23	and	and	CC
cord-309582-ihrj84hr	153	24	the	the	DT
cord-309582-ihrj84hr	153	25	health	health	NN
cord-309582-ihrj84hr	153	26	professions	profession	NNS
cord-309582-ihrj84hr	154	1	FDA	FDA	NNP
cord-309582-ihrj84hr	154	2	guidance	guidance	NN
cord-309582-ihrj84hr	154	3	on	on	IN
cord-309582-ihrj84hr	154	4	conduct	conduct	NN
cord-309582-ihrj84hr	154	5	of	of	IN
cord-309582-ihrj84hr	154	6	clinical	clinical	JJ
cord-309582-ihrj84hr	154	7	trials	trial	NNS
cord-309582-ihrj84hr	154	8	of	of	IN
cord-309582-ihrj84hr	154	9	medical	medical	JJ
cord-309582-ihrj84hr	154	10	products	product	NNS
cord-309582-ihrj84hr	154	11	during	during	IN
cord-309582-ihrj84hr	154	12	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	154	13	pandemic	pandemic	NN
cord-309582-ihrj84hr	154	14	:	:	:
cord-309582-ihrj84hr	154	15	guidance	guidance	NN
cord-309582-ihrj84hr	154	16	for	for	IN
cord-309582-ihrj84hr	154	17	industry	industry	NN
cord-309582-ihrj84hr	154	18	,	,	,
cord-309582-ihrj84hr	154	19	investigators	investigator	NNS
cord-309582-ihrj84hr	154	20	,	,	,
cord-309582-ihrj84hr	154	21	and	and	CC
cord-309582-ihrj84hr	154	22	institutional	institutional	JJ
cord-309582-ihrj84hr	154	23	review	review	NN
cord-309582-ihrj84hr	154	24	boards	board	NNS
cord-309582-ihrj84hr	154	25	.	.	.
cord-309582-ihrj84hr	155	1	US	US	NNP
cord-309582-ihrj84hr	155	2	Food	Food	NNP
cord-309582-ihrj84hr	155	3	and	and	CC
cord-309582-ihrj84hr	155	4	Drug	Drug	NNP
cord-309582-ihrj84hr	155	5	Administration	Administration	NNP
cord-309582-ihrj84hr	155	6	EMA	EMA	NNP
cord-309582-ihrj84hr	155	7	Guidance	Guidance	NNP
cord-309582-ihrj84hr	155	8	on	on	IN
cord-309582-ihrj84hr	155	9	the	the	DT
cord-309582-ihrj84hr	155	10	Management	Management	NNP
cord-309582-ihrj84hr	155	11	of	of	IN
cord-309582-ihrj84hr	155	12	Clinical	Clinical	NNP
cord-309582-ihrj84hr	155	13	Trials	Trials	NNPS
cord-309582-ihrj84hr	155	14	during	during	IN
cord-309582-ihrj84hr	155	15	the	the	DT
cord-309582-ihrj84hr	155	16	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	155	17	(	(	-LRB-
cord-309582-ihrj84hr	155	18	Coronavirus	Coronavirus	NNP
cord-309582-ihrj84hr	155	19	)	)	-RRB-
cord-309582-ihrj84hr	155	20	pandemic	pandemic	NN
cord-309582-ihrj84hr	155	21	.	.	.
cord-309582-ihrj84hr	156	1	The	the	DT
cord-309582-ihrj84hr	156	2	European	European	NNP
cord-309582-ihrj84hr	156	3	Medicines	Medicines	NNPS
cord-309582-ihrj84hr	156	4	Agency	Agency	NNP
cord-309582-ihrj84hr	157	1	Treating	treat	VBG
cord-309582-ihrj84hr	157	2	COVID-19-Off	COVID-19-Off	NNP
cord-309582-ihrj84hr	157	3	-	-	HYPH
cord-309582-ihrj84hr	157	4	Label	Label	NNP
cord-309582-ihrj84hr	157	5	Drug	drug	NN
cord-309582-ihrj84hr	157	6	Use	Use	NNP
cord-309582-ihrj84hr	157	7	,	,	,
cord-309582-ihrj84hr	157	8	Compassionate	compassionate	JJ
cord-309582-ihrj84hr	157	9	Use	Use	NNP
cord-309582-ihrj84hr	157	10	,	,	,
cord-309582-ihrj84hr	157	11	and	and	CC
cord-309582-ihrj84hr	157	12	Randomized	Randomized	NNP
cord-309582-ihrj84hr	157	13	Clinical	Clinical	NNP
cord-309582-ihrj84hr	157	14	Trials	Trials	NNPS
cord-309582-ihrj84hr	157	15	During	during	IN
cord-309582-ihrj84hr	157	16	Pandemics	pandemic	NNS
cord-309582-ihrj84hr	157	17	Creating	create	VBG
cord-309582-ihrj84hr	157	18	a	a	DT
cord-309582-ihrj84hr	157	19	Framework	framework	NN
cord-309582-ihrj84hr	157	20	for	for	IN
cord-309582-ihrj84hr	157	21	Conducting	conduct	VBG
cord-309582-ihrj84hr	157	22	Randomized	Randomized	NNP
cord-309582-ihrj84hr	157	23	Clinical	Clinical	NNP
cord-309582-ihrj84hr	157	24	Trials	Trials	NNPS
cord-309582-ihrj84hr	157	25	during	during	IN
cord-309582-ihrj84hr	157	26	Disease	Disease	NNP
cord-309582-ihrj84hr	157	27	Outbreaks	Outbreaks	NNPS
cord-309582-ihrj84hr	157	28	Modernising	Modernising	NNP
cord-309582-ihrj84hr	157	29	epidemic	epidemic	NN
cord-309582-ihrj84hr	157	30	science	science	NN
cord-309582-ihrj84hr	157	31	:	:	:
cord-309582-ihrj84hr	158	1	enabling	enable	VBG
cord-309582-ihrj84hr	158	2	patient	patient	NN
cord-309582-ihrj84hr	158	3	-	-	HYPH
cord-309582-ihrj84hr	158	4	centred	centre	VBN
cord-309582-ihrj84hr	158	5	research	research	NN
cord-309582-ihrj84hr	158	6	during	during	IN
cord-309582-ihrj84hr	158	7	epidemics	epidemic	NNS
cord-309582-ihrj84hr	158	8	Director	Director	NNP
cord-309582-ihrj84hr	158	9	-	-	HYPH
cord-309582-ihrj84hr	158	10	General	General	NNP
cord-309582-ihrj84hr	158	11	's	's	POS
cord-309582-ihrj84hr	158	12	opening	opening	NN
cord-309582-ihrj84hr	158	13	remarks	remark	NNS
cord-309582-ihrj84hr	158	14	at	at	IN
cord-309582-ihrj84hr	158	15	the	the	DT
cord-309582-ihrj84hr	158	16	media	medium	NNS
cord-309582-ihrj84hr	158	17	briefing	briefing	NN
cord-309582-ihrj84hr	158	18	on	on	IN
cord-309582-ihrj84hr	158	19	COVID-19	COVID-19	NNP
cord-309582-ihrj84hr	158	20	Advancing	Advancing	NNP
cord-309582-ihrj84hr	158	21	preparedness	preparedness	NN
cord-309582-ihrj84hr	158	22	for	for	IN
cord-309582-ihrj84hr	158	23	clinical	clinical	JJ
cord-309582-ihrj84hr	158	24	research	research	NN
cord-309582-ihrj84hr	158	25	during	during	IN
cord-309582-ihrj84hr	158	26	infectious	infectious	JJ
cord-309582-ihrj84hr	158	27	disease	disease	NN
cord-309582-ihrj84hr	158	28	epidemics	epidemic	NNS
cord-309582-ihrj84hr	158	29	Research	Research	NNP
cord-309582-ihrj84hr	158	30	as	as	IN
cord-309582-ihrj84hr	158	31	a	a	DT
cord-309582-ihrj84hr	158	32	part	part	NN
cord-309582-ihrj84hr	158	33	of	of	IN
cord-309582-ihrj84hr	158	34	public	public	JJ
cord-309582-ihrj84hr	158	35	health	health	NN
cord-309582-ihrj84hr	158	36	emergency	emergency	NN
cord-309582-ihrj84hr	158	37	response	response	NN
cord-309582-ihrj84hr	159	1	The	the	DT
cord-309582-ihrj84hr	159	2	n	n	JJ
cord-309582-ihrj84hr	159	3	-	-	HYPH
cord-309582-ihrj84hr	159	4	of-1	of-1	JJ
cord-309582-ihrj84hr	159	5	clinical	clinical	JJ
cord-309582-ihrj84hr	159	6	trial	trial	NN
cord-309582-ihrj84hr	159	7	:	:	:
cord-309582-ihrj84hr	159	8	the	the	DT
cord-309582-ihrj84hr	159	9	ultimate	ultimate	JJ
cord-309582-ihrj84hr	159	10	strategy	strategy	NN
cord-309582-ihrj84hr	159	11	for	for	IN
cord-309582-ihrj84hr	159	12	individualizing	individualize	VBG
cord-309582-ihrj84hr	159	13	medicine	medicine	NN
cord-309582-ihrj84hr	159	14	?	?	.
cord-309582-ihrj84hr	160	1	Performance	performance	NN
cord-309582-ihrj84hr	160	2	of	of	IN
cord-309582-ihrj84hr	160	3	different	different	JJ
cord-309582-ihrj84hr	160	4	clinical	clinical	JJ
cord-309582-ihrj84hr	160	5	trial	trial	NN
cord-309582-ihrj84hr	160	6	designs	design	NNS
cord-309582-ihrj84hr	160	7	to	to	TO
cord-309582-ihrj84hr	160	8	evaluate	evaluate	VB
cord-309582-ihrj84hr	160	9	treatments	treatment	NNS
cord-309582-ihrj84hr	160	10	during	during	IN
cord-309582-ihrj84hr	160	11	an	an	DT
cord-309582-ihrj84hr	160	12	epidemic	epidemic	NN
cord-309582-ihrj84hr	160	13	Ethical	ethical	JJ
cord-309582-ihrj84hr	160	14	Rationale	rationale	NN
cord-309582-ihrj84hr	160	15	for	for	IN
cord-309582-ihrj84hr	160	16	the	the	DT
cord-309582-ihrj84hr	160	17	Ebola	Ebola	NNP
cord-309582-ihrj84hr	160	18	"	"	``
cord-309582-ihrj84hr	160	19	Ring	Ring	NNP
cord-309582-ihrj84hr	160	20	Vaccination	vaccination	NN
cord-309582-ihrj84hr	160	21	"	"	''
cord-309582-ihrj84hr	160	22	Trial	Trial	NNP
cord-309582-ihrj84hr	160	23	Design	Design	NNP
cord-309582-ihrj84hr	160	24	Designing	design	VBG
cord-309582-ihrj84hr	160	25	cell	cell	NN
cord-309582-ihrj84hr	160	26	lines	line	NNS
cord-309582-ihrj84hr	160	27	for	for	IN
cord-309582-ihrj84hr	160	28	viral	viral	JJ
cord-309582-ihrj84hr	160	29	vaccine	vaccine	NN
cord-309582-ihrj84hr	160	30	production	production	NN
cord-309582-ihrj84hr	160	31	:	:	:
cord-309582-ihrj84hr	160	32	Where	where	WRB
cord-309582-ihrj84hr	160	33	do	do	VBP
cord-309582-ihrj84hr	160	34	we	-PRON-	PRP
cord-309582-ihrj84hr	160	35	stand	stand	VB
cord-309582-ihrj84hr	160	36	?	?	.
cord-309582-ihrj84hr	161	1	Cell	cell	NN
cord-309582-ihrj84hr	161	2	Lines	line	NNS
cord-309582-ihrj84hr	161	3	:	:	:
cord-309582-ihrj84hr	162	1	A	a	DT
cord-309582-ihrj84hr	162	2	Tool	tool	NN
cord-309582-ihrj84hr	162	3	for	for	IN
cord-309582-ihrj84hr	162	4	In	in	IN
cord-309582-ihrj84hr	162	5	Vitro	Vitro	NNP
cord-309582-ihrj84hr	162	6	Drug	Drug	NNP
cord-309582-ihrj84hr	162	7	Metabolism	Metabolism	NNP
cord-309582-ihrj84hr	162	8	Studies	Studies	NNPS
cord-309582-ihrj84hr	162	9	Cell	cell	NN
cord-309582-ihrj84hr	162	10	culture	culture	NN
cord-309582-ihrj84hr	162	11	processes	process	NNS
cord-309582-ihrj84hr	162	12	for	for	IN
cord-309582-ihrj84hr	162	13	monoclonal	monoclonal	JJ
cord-309582-ihrj84hr	162	14	antibody	antibody	NN
cord-309582-ihrj84hr	162	15	production	production	NN
cord-309582-ihrj84hr	162	16	Guidelines	guideline	NNS
cord-309582-ihrj84hr	162	17	for	for	IN
cord-309582-ihrj84hr	162	18	the	the	DT
cord-309582-ihrj84hr	162	19	use	use	NN
cord-309582-ihrj84hr	162	20	of	of	IN
cord-309582-ihrj84hr	162	21	cell	cell	NN
cord-309582-ihrj84hr	162	22	lines	line	NNS
cord-309582-ihrj84hr	162	23	in	in	IN
cord-309582-ihrj84hr	162	24	biomedical	biomedical	JJ
cord-309582-ihrj84hr	162	25	research	research	NN
cord-309582-ihrj84hr	163	1	The	the	DT
cord-309582-ihrj84hr	163	2	flaws	flaw	NNS
cord-309582-ihrj84hr	163	3	and	and	CC
cord-309582-ihrj84hr	163	4	human	human	JJ
cord-309582-ihrj84hr	163	5	harms	harm	NNS
cord-309582-ihrj84hr	163	6	of	of	IN
cord-309582-ihrj84hr	163	7	animal	animal	NN
cord-309582-ihrj84hr	163	8	experimentation	experimentation	NN
cord-309582-ihrj84hr	163	9	Care	care	VB
cord-309582-ihrj84hr	163	10	for	for	IN
cord-309582-ihrj84hr	163	11	laboratory	laboratory	NN
cord-309582-ihrj84hr	163	12	animals	animal	NNS
cord-309582-ihrj84hr	163	13	during	during	IN
cord-309582-ihrj84hr	163	14	COVID-19	covid-19	JJ
cord-309582-ihrj84hr	163	15	crisis	crisis	NN
cord-309582-ihrj84hr	163	16	Science	Science	NNP
cord-309582-ihrj84hr	163	17	-	-	HYPH
cord-309582-ihrj84hr	163	18	ing	e	VBG
cord-309582-ihrj84hr	163	19	from	from	IN
cord-309582-ihrj84hr	163	20	home	home	NN