id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-272512-gevrlcvy	Shewen, P.E.	Challenges in mucosal vaccination of cattle	2009-03-15		.txt	text/plain	4849	205	35	Mucosal immunity Vaccination Mannheimia haemolytica Cattle A B S T R A C T Recognition of the mucosal portal of entry for many infectious diseases and of the relevance of mucosal immune response to protection has encouraged the development of vaccines administered by mucosal routes, principally oral and intranasal, for stimulation of intestinal and nasopharyngeal lymphoid tissues respectively. An increase in anti-leukotoxin (Lkt) IgA was demonstrated in nasal secretions of calves following feeding of alfalfa expressing a truncated Lkt50 from Mannheimia haemolytica, and there is evidence suggesting that such vaccination may protect against experimentally induced pneumonia. An increase in anti-leukotoxin (Lkt) IgA was demonstrated in nasal secretions of calves following feeding of alfalfa expressing a truncated Lkt50 from Mannheimia haemolytica, and there is evidence suggesting that such vaccination may protect against experimentally induced pneumonia.	./cache/cord-272512-gevrlcvy.txt	./txt/cord-272512-gevrlcvy.txt