id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-102246-2lmq9s4l	Salvadori, Marcia R.	Morphological and intracellular alterations induced by cytotoxin VT2y produced by Escherichia coli isolated from chickens with swollen head syndrome	2001-04-01		.txt	text/plain	2380	131	56	title: Morphological and intracellular alterations induced by cytotoxin VT2y produced by Escherichia coli isolated from chickens with swollen head syndrome Abstract Recently, a novel verocytotoxin named VT2y was described which belongs to the STx family and is produced by Escherichia coli isolated from domestic poultry with swollen head syndrome (SHS). The VT2y toxin induced apoptosis in Vero, HeLa, CHO, CEF (primary chicken embryo fibroblast) and PCK (primary chicken kidney) cell lines. The aim of this study is to illustrate the morphological and intracellular alterations induced in vitro by cytotoxin VT2y in Vero, HeLa, CHO, HEp-2, PCK and CEF cell lines. The cytotoxin VT2y caused morphological alterations in Vero cells, such as cytoplasm vacuolization, blebbing of the plasma membrane, chromatin condensation within the nucleus, nuclear shrinkage and apoptotic bodies within 15 min. Escherichia coli strains isolated from pigs with edema disease produce a variant of Shiga-like toxin II Cytotoxin produced by Escherichia coli isolated from chickens with swollen head syndrome (SHS)	./cache/cord-102246-2lmq9s4l.txt	./txt/cord-102246-2lmq9s4l.txt