id author title date pages extension mime words sentences flesch summary cache txt cord-265263-r9e6bop3 Kassaa, Imad Al Vaginal Lactobacillusgasseri CMUL57 can inhibit herpes simplex type 2 but not Coxsackievirus B4E2 2015-03-10 .txt text/plain 3860 224 56 Tested lactobacilli displayed anti-HSV-2 activity when they were co-incubated with the virus prior to inoculating the mixture to Vero cell monolayers. This study shows that antiviral activity is due to the direct interaction between probiotic strains and enveloped virus. plantarum CMUL140 strain with HSV-2 on Vero cell monolayers has increased the cells viability by 65, 35 and 15 %, respectively, as compared to the control with 22 % viability, after exposure to the virus (Fig. 3a) . plantarum CMUL140-derived neutralized supernatants enhanced slightly the viability of Vero cell monolayer inoculated with 100 PFU HSV-2 with about 9.5, 5.4 and 2.4 %, respectively, due to reduction in viral infectious particles. gasseri CMUL57 at 10 8 CFU/ml or Dulbecco's Modified Eagle's Medium (DMEM, negative control) were incubated for 2 h at 37 °C in CO 2 atmosphere in the presence of HSV-2 (10 4 PFU/ml) or CVB4E2 (10 3 TCID 50 /ml). ./cache/cord-265263-r9e6bop3.txt ./txt/cord-265263-r9e6bop3.txt