id author title date pages extension mime words sentences flesch summary cache txt cord-002338-ri7v2ka3 Anderson, Tavis K. A Phylogeny-Based Global Nomenclature System and Automated Annotation Tool for H1 Hemagglutinin Genes from Swine Influenza A Viruses 2016-12-14 .txt text/plain 5842 276 42 A common global nomenclature facilitates comparisons of IAVs infecting humans and pigs, within and between regions, and can provide insight into the diversity of swine H1 influenza virus and its impact on vaccine strain selection, diagnostic reagents, and test performance, thereby simplifying communication of such data. Similarly, IAV in Asia reflects the regional introduction and subsequent evolution and cocirculation of multiple genetic clades of classical-swine H1N1, avian-like H1N1, and human seasonal-like H1N1 and H1N2 viruses (6, 27, 28) . Three major first-order H1 lineages continued to circulate in pigs ( Fig. 1 ; also see Fig. S1 in the supplemental material): the 1A classical lineage, viruses related to the 1918 human influenza pandemic; the 1B human seasonal lineage, the result of multiple human-to-swine transmission episodes of human seasonal H1 strains over decades; and the 1C Eurasian avian lineage, arising from an introduction from wild birds into pigs in the 1970s. ./cache/cord-002338-ri7v2ka3.txt ./txt/cord-002338-ri7v2ka3.txt