id author title date pages extension mime words sentences flesch summary cache txt cord-002728-6oyw5sqv Carding, S. R. Review article: the human intestinal virome in health and disease 2017-09-04 .txt text/plain 4362 250 40 2 With the advent of new, sequence-based technologies that do not rely on the ability to isolate viruses for their identification, it is now possible to define and characterise viruses in different environmental samples in greater detail than ever before, which has resulted in an increased interest in the role the viral assemblage of the human gut microbiota plays in health and disease. The genetic content of VLPs comprising bacteriophages (phages) that infect bacteria and archaea and, to a much lesser extent, human-, plant-, amoebae-and animal-infecting viruses found along the GI tract constitute the human intestinal virome (Figure 1 ). Analyses of metagenomic sequence data provide detailed information on phage-host and phage-phage competition within the human faecal microbiome, implying CRISPR spacers are actively and continuously acquired by prokaryotes in response to the presence of phages in the GI tract. ./cache/cord-002728-6oyw5sqv.txt ./txt/cord-002728-6oyw5sqv.txt