id author title date pages extension mime words sentences flesch summary cache txt cord-002921-i5jxn1vj Morens, David M Pandemic Zika: A Formidable Challenge to Medicine and Public Health 2017-12-15 .txt text/plain 1978 104 42 Because of the pandemic's uniqueness and the insidious ability of Zika virus to harm unborn children, the pandemic has captured the attention of infectious disease researchers and practitioners of clinical and public health medicine around the world, as well as the attention of allied colleagues working in entomology, vector control, informatics, teratology, immunology, and a host of other disciplines [3] [4] [5] . Furthermore, some studies have suggested that preexisting flavivirus immunity (eg, from prior dengue virus infection) might potentiate Zika [16] via antibody-dependent infection enhancement in some circumstances [17] , while other research has countered this view [18] . As with most flaviviruses, small-animal models of Zika virus infection and disease have been problematic, but considerable progress has nonetheless been made, including important new information bearing on teratogenicity and vaccine design strategy [20] . Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes ./cache/cord-002921-i5jxn1vj.txt ./txt/cord-002921-i5jxn1vj.txt