id author title date pages extension mime words sentences flesch summary cache txt cord-004781-ajf9zig0 Ray, N. B. Rabies viruses infect primary cultures of murine, feline, and human microglia and astrocytes 2014-03-07 .txt text/plain 2337 125 43 Primary cultures of murine, feline, and human microglia and astrocytes were infected with several different rabies viruses: two unpassaged street virus isolates, a cell culture-adapted strain, and a mouse brain-passaged strain. Primary cultures of murine, feline, and human microglia and astrocytes were infected with several different rabies viruses: two unpassaged street virus isolates, a cell culture-adapted strain, and a mouse brain-passaged strain. In addition, a number of studies have reported rabies viral antigens and virions in human [1, 13, 29] and murine astrocytes [10, 18, 23] , and in murine ramiĀ®ed microglial cells [27] , begging the question of the role of these cells in viral replication and persistence, as well as pathogenesis. In the present study, as an initial step toward evaluation of the potential involvement of these glial cells in rabies virus infections, we have directly examined the ability of different rabies virus strains and isolates to infect and replicate in primary cultures of microglia and astrocytes. ./cache/cord-004781-ajf9zig0.txt ./txt/cord-004781-ajf9zig0.txt