id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004827-bnf3mvaf	Desselberger, U.	Report on an ICTV-sponsored symposium on Virus Evolution	2005-01-13		.txt	text/plain	2766	164	48	Phylogenetic relationships have been found useful for virus identification, work on origin, speed and mechanisms of evolution, taxonomy, and the elucidation of transmission pathways (e.g. the transmission of HIV from a source to a victim [16] ). In vitro, a single round of replication of HIV-1 in T lymphocytes generated on average 9 recombination events per virus [14] . Approximately 50% of sequence changes are consistent with evolution by point mutations; other changes are due to multiple recombination events. After an introduction in which basic genetic terms were defined (mutation and mutation rate, hypermutation, recombination, reassortment, segmentation etc), the quasispecies concept was presented according to which any sample of an RNA virus represents a 'swarm' of closely related mutants. 'To maintain RNA structure, evolution selects against better alternatives elsewhere in the genome'. The aim of the talk was to show the significance of RNA structural considerations for the evolution of viruses. Plant RNA virus evolution	./cache/cord-004827-bnf3mvaf.txt	./txt/cord-004827-bnf3mvaf.txt