id author title date pages extension mime words sentences flesch summary cache txt cord-006106-u5npu6ng Attoui, H. Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses 2002 .txt text/plain 7023 357 51 We report a genomic and morphologic study of the European Eyach (EYA) virus (genus Coltivirus, family Reoviridae) and a comparative analysis with the American Colorado tick fever (CTF) virus (the type species of the genus). These findings, together with the comparative analysis to genomes of south-east Asian isolates, support the recent classification of arboviruses with 12 segments of dsRNA within two distinct genera (genus Coltivirus and genus Seadornavirus) and raise interesting questions about the evolutionary origins of coltiviruses. Analyses of VP5 showed the presence of a potential phosphamide linkage site (amino acid 342-347 of CTF virus: LNYDKY and for EYA virus: LNYIKH) comparable to that found in the protein encoded by segment 2 of members of the genus Orthoreovirus (position 1166-1171: ANPDKF, 40). Sequence determination and analysis of the full-length genome of Colorado tick fever virus, the type species of genus Coltivirus (family Reoviridae) ./cache/cord-006106-u5npu6ng.txt ./txt/cord-006106-u5npu6ng.txt