id author title date pages extension mime words sentences flesch summary cache txt cord-007094-ur9sz21s Mahabir, Esther Rodent and Germplasm Trafficking: Risks of Microbial Contamination in a High-Tech Biomedical World 2008-01-01 .txt text/plain 6254 268 39 Preservation of mouse germ-plasm is achieved by cryopreservation of spermatozoa, embryos, or ovaries, and embryonic stem cells are used for the production of genetically engineered mice. In this article, we discuss regulations and practical issues in the shipping of live mice and mouse tissues, including spermatozoa, embryos, ovaries, and embryonic stem cells, and review work on microbial contamination of these biological materials. The importation paperwork for cryopreserved laboratory mouse tissues and cell lines is similar to that required for live animal importation to the United States (i.e., a pro forma invoice and declaration statements). Embryo transfer recipients in rederivation programs should be held in individually ventilated cages (IVCs 1 ) until testing shows that they are free of all unwanted microorganisms, including those listed in Appendix 3 of the Federation of Laboratory Animal Science Associations (FELASA) recommendations (Nicklas et al. Risk assessment of mouse hepatitis virus infection via in vitro fertilization and embryo transfer by the use of zona-intact and laser-microdissected oocytes ./cache/cord-007094-ur9sz21s.txt ./txt/cord-007094-ur9sz21s.txt