id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007784-fq2urilg	Elderfield, Ruth	Influenza Pandemics	2011-09-22		.txt	text/plain	10484	539	51	H5N1 virus has been responsible for over 500 cases of human infection and 300 deaths (as of 31st August 2010 according to the World Health Organisation avian influenza surveillance system) but thankfully has not yet reassorted with a human-adapted influenza virus, nor given rise to a pandemic outbreak [45] . For avian influenza viruses to adapt to and transmit between humans, it is now apparent that in addition to the reassortment events that occur during antigenic shift, their HA proteins must also undergo modifications that alter their fine receptor binding specificity. However, the human seasonal virus had changed so dramatically that it shared only 79% amino acids with the 1918 HA protein, and this did not allow for any antigenic cross protection for humans who had been infected with seasonal H1 in recent years against the novel 2009 pandemic strain.	./cache/cord-007784-fq2urilg.txt	./txt/cord-007784-fq2urilg.txt