id author title date pages extension mime words sentences flesch summary cache txt cord-007792-596jxrm5 Luo, Ming Influenza Virus Entry 2011-08-26 .txt text/plain 12446 635 56 The key player in virus entry is the surface glycoprotein HA that contains the host receptor binding site to allow the virus particle to attach to specifi c host cells, the fusion peptide that is inserted into the target cellular membrane during membrane fusion, and other structural elements that may refold during the membrane fusion process. When the HA amino acid substitutions are accumulated in the repertoire of infl uenza virus strains, they are mostly on the exposed surface of the HA glycoprotein except for the receptor binding site, the fusion peptide, and the amino acids that accommodate the fusion peptide before HA structural changes for membrane fusion (Wilson et al. The next 18 amino acids form part of the pocket that accommodates the hydrophobic fusion peptide in the metastable HA structure on the infl uenza virion prior to virus entry. ./cache/cord-007792-596jxrm5.txt ./txt/cord-007792-596jxrm5.txt