id author title date pages extension mime words sentences flesch summary cache txt cord-008556-oetrdm8g Kozak, Marilyn Regulation of Protein Synthesis in Virus-Infected Animal Cells 2008-03-01 .txt text/plain 23945 1270 51 One consequence of the scanning mechanism is that deleting the "ribosome binding site" (i.e., the normal initiator codon and flanking sequences) will not abolish translation; ribosomes will simply use the next AUG codon downstream, which, in some cases, has been shown to direct the synthesis of a biologically active, truncated protein (Downey et al., 1984; Halpern and Smiley, 1984; Katinka and Yaniv, 1982) . The best evidence for this is the ability of both EMC and SFV 26 S mRNA to be translated in EMC virus-infected cells, in which host translation is drastically inhibited by a mechanism that has not been difined, but that clearly does not involve cap binding protein (Mosenkis et al., 1985) . In wild-type adenovirus-infected cells, in which host protein synthesis is drastically reduced, both adenovirus and influenza virus mRNAs are translated efficiently. ./cache/cord-008556-oetrdm8g.txt ./txt/cord-008556-oetrdm8g.txt