id author title date pages extension mime words sentences flesch summary cache txt cord-009561-pg4jmvw4 Johnson, Richard T. The virology of demyelinating diseases 2004-10-08 .txt text/plain 3602 204 34 The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and "viral" infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections in humans can cause diseases with long incubation periods, remitting and relapsing courses, and demyelination, and (3) patients with multiple sclerosis have abnormal immune responses to viruses. Thud, studies of patients with multiple sclerosis consistently have shown higher levels of antibody against measles virus in serum and cerebrospinal fluid (CSF) than in controls and in some studies antibodies have been elevated to other viral agents as well (Table 2) . In studies of CSF we found no intrathecal synthesis of antibody in posuneasles encephalomyelitis to suggest antigenic stimulation Subsequently, a variety of diseases of the central and peripheral nervous system and muscle have been described as complications of HIV infection [58, 591. ./cache/cord-009561-pg4jmvw4.txt ./txt/cord-009561-pg4jmvw4.txt